Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" ACP2 LAP ENSG00000134575 "Acid phosphatase 2, lysosomal" P11117 11 47239302-47248906 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 30.3" "Lineage enriched" "Detected in all" 5 "monocytes: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" 8100 "unprognostic (5.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.86e-2)" "prognostic favourable (1.04e-4)" "unprognostic (7.90e-3)" "unprognostic (2.93e-1)" "unprognostic (6.16e-3)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (3.28e-3)" "unprognostic (2.64e-3)" "unprognostic (5.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (8.68e-3)" "unprognostic (1.57e-1)" 15.7 23.6 13.1 13.9 13.6 3.6 13.0 12.5 19.5 11.3 15.4 11.7 15.4 26.9 10.5 20.0 8.9 9.3 12.4 18.1 14.4 18.2 18.7 65.4 13.3 40.7 11.8 12.7 8.1 36.2 13.6 13.8 31.3 12.2 15.3 11.7 16.4 32.3 18.5 10.1 7.0 24.4 10.8 11.0 18.9 14.2 14.6 7.1 10.0 12.4 9.6 9.7 14.3 8.0 1.0 6.6 4.6 30.3 3.8 5.6 4.2 6.7 14.0 13.6 12.0 12.2 6.1 10.5 11.1 19.9 20.4 21.3 9.6 11.1 1.8 9.2 14.2 10.0 7.1 10.3 9.9 34.6 12.2 4.5 20.6 10.1 17.0 6.7 11.7 14.9 6.5 10.6 6.2 14.7 8.2 14.6 13.3 10.9 5.5 6.0 9.4 8.5 4.3 18.4 14.7 15.2 15.7 7.2 11.2 15.4 34.3 7.9 20.9 5.9 8.7 10.4 8.7 13.5 15.8 12.2 15.7 1.5 15.3 3.4 15.8 4.6 7.2 3.0 5.6 30.3 4.4 1.0 3.5 5.0 6.6 0.7 3.1 2.7 1.2 3.8 19.5 0.2 3.6 4.2 13.1 13.6 12.5 19.5 14.4 18.2 11.8 12.7 12.2 7.1 ADA ENSG00000196839 "Adenosine deaminase" P00813 20 44619522-44652233 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease mutation, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 64.0;intestine: 142.2;lymphoid tissue: 99.0" "Cell line enriched" "Detected in many" 8 "MOLT-4: 197.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 64.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001399, CAB004307, HPA023884" Enhanced Supported "Plasma membrane,Cytosol" 650000 "Plasma membrane" Cytosol "CAB004307: AB_626634, HPA001399: AB_1078099, HPA023884: AB_1844573" "unprognostic (4.30e-2)" "unprognostic (6.89e-2)" "unprognostic (3.96e-2)" "prognostic unfavourable (1.23e-7)" "unprognostic (9.33e-2)" "unprognostic (9.07e-3)" "prognostic unfavourable (6.77e-5)" "prognostic unfavourable (2.20e-4)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-1)" "prognostic unfavourable (2.94e-14)" "unprognostic (2.29e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" 8.1 3.2 2.5 5.4 6.5 5.3 5.1 0.9 5.0 2.8 7.4 5.0 1.8 142.2 1.7 3.4 4.6 2.4 3.0 9.2 2.7 0.8 1.3 2.1 2.8 8.9 3.6 2.3 1.2 2.4 0.8 0.3 1.8 3.9 1.8 1.5 0.7 2.6 1.3 2.0 2.8 5.0 2.1 1.3 9.5 19.7 1.6 6.1 99.0 2.8 2.1 7.6 3.6 2.6 1.3 41.6 0.5 64.0 16.9 10.3 9.6 1.4 3.9 2.0 1.3 3.9 5.4 3.3 1.4 0.8 1.4 1.0 1.8 1.5 4.0 1.7 1.8 0.2 1.4 5.8 0.8 0.3 1.8 0.8 0.7 1.4 1.6 0.6 2.1 26.1 2.5 0.5 0.9 5.4 2.0 3.3 0.6 3.4 197.1 2.9 0.5 1.4 10.6 2.8 9.8 0.2 0.0 0.0 0.9 2.1 0.4 2.5 0.4 1.9 1.7 1.0 2.0 2.2 0.2 4.3 2.7 8.3 0.3 3.3 0.9 0.0 1.8 0.2 8.7 30.7 5.7 1.3 7.3 10.3 6.8 1.0 5.7 8.1 0.5 16.9 64.0 41.6 5.3 9.6 2.5 6.5 0.9 5.0 2.7 0.8 3.6 2.3 3.9 6.1 ADK AK ENSG00000156110 "Adenosine kinase" P55263 10 74151185-74709303 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Purine salvage" "Kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 71.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032876, HPA038391, HPA038409" Approved Supported Nucleoplasm,Cytosol 320000 "Nucleoplasm, Cytosol" "CAB032876: AB_2242229, HPA038391: , HPA038409: AB_10675798" "unprognostic (1.55e-3)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.62e-2)" "unprognostic (2.52e-2)" "prognostic unfavourable (1.93e-4)" "prognostic favourable (9.91e-4)" "unprognostic (2.64e-1)" "unprognostic (2.88e-1)" "unprognostic (1.55e-1)" "unprognostic (8.15e-3)" "unprognostic (2.51e-1)" "unprognostic (1.89e-3)" "unprognostic (2.03e-1)" "unprognostic (2.88e-2)" "unprognostic (4.97e-3)" "unprognostic (2.95e-2)" 13.8 10.7 11.8 13.6 25.4 12.1 14.5 11.2 11.8 9.5 9.3 9.0 9.6 8.8 6.6 10.6 29.4 8.9 6.3 15.7 9.8 11.1 19.0 71.9 15.1 17.9 12.3 9.3 5.2 12.6 15.1 23.5 43.2 11.6 8.7 10.8 8.5 13.1 11.4 18.1 20.8 6.4 8.3 13.2 11.3 7.4 11.9 10.3 13.4 20.8 24.1 21.9 12.6 14.7 49.3 23.0 5.4 21.6 6.5 15.7 9.8 37.5 8.5 9.0 12.0 9.0 13.9 20.7 32.6 25.9 25.3 28.4 23.7 39.2 19.7 8.2 13.1 34.4 10.5 34.7 40.6 13.2 12.1 12.5 13.9 25.5 10.3 20.0 5.1 12.8 23.0 18.4 45.9 22.0 9.9 6.4 19.0 21.0 23.5 27.1 2.5 60.0 22.7 15.6 16.9 27.7 20.7 7.1 8.4 14.3 55.8 10.8 37.1 15.1 18.8 8.4 15.5 22.4 26.9 9.2 10.4 22.2 15.9 28.8 5.1 1.3 10.1 1.4 4.5 18.0 10.0 29.7 9.5 8.2 23.0 49.3 7.9 6.5 5.4 6.5 21.6 16.7 15.7 9.8 11.8 25.4 11.2 11.8 9.8 11.1 12.3 9.3 11.6 10.3 ADPRM "C17orf48, MDS006" ENSG00000170222 "ADP-ribose/CDP-alcohol diphosphatase, manganese dependent" Q3LIE5 17 10697594-10711233 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023265, HPA023820" Approved "HPA023265: AB_1845590, HPA023820: AB_1845591" "unprognostic (7.58e-3)" "prognostic favourable (1.69e-4)" "unprognostic (1.42e-1)" "prognostic favourable (2.38e-5)" "unprognostic (2.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.43e-1)" "unprognostic (6.26e-3)" "unprognostic (2.97e-1)" "unprognostic (6.53e-3)" "unprognostic (2.65e-2)" "unprognostic (1.83e-1)" "unprognostic (4.77e-2)" "unprognostic (5.97e-2)" 11.1 8.2 6.4 9.3 13.1 12.9 13.0 9.8 12.2 10.3 8.1 10.1 16.1 6.6 11.3 9.1 7.8 9.0 7.9 6.4 9.6 6.1 7.8 15.2 6.9 23.2 8.1 5.6 14.2 12.4 4.2 11.9 4.9 9.3 16.7 7.5 8.3 8.8 13.4 14.8 9.2 9.9 6.5 7.3 10.5 12.2 9.5 8.2 18.8 14.6 10.4 11.1 8.8 9.0 10.5 4.2 6.1 3.5 4.0 18.7 5.9 4.1 2.2 4.5 5.3 10.4 13.4 2.2 7.8 8.7 5.7 8.6 1.3 1.9 8.0 4.2 8.2 3.4 1.9 5.6 6.8 5.1 5.3 5.8 3.6 4.4 18.6 3.0 5.4 15.4 10.3 6.0 9.0 10.0 3.9 1.5 8.2 1.1 3.8 5.3 3.7 2.1 3.4 5.2 2.4 10.0 3.0 1.0 6.3 4.1 1.6 9.7 3.8 5.9 10.2 4.0 2.4 4.4 5.2 2.0 1.4 2.3 7.8 4.4 6.7 3.4 3.5 6.1 3.2 3.0 5.4 8.2 8.8 5.8 4.2 10.5 18.7 12.0 2.5 4.0 3.1 2.4 7.7 5.9 6.4 13.1 9.8 12.2 9.6 6.1 8.1 5.6 9.3 8.2 AICDA "AID, ARP2, CDA2, HIGM2" ENSG00000111732 "Activation induced cytidine deaminase" Q9GZX7 12 8602166-8612871 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 6.6;lymphoid tissue: 22.3" "Group enriched" "Detected in some" 6 "Daudi: 48.4;U-698: 40.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 6.6" "Group enriched" "Detected in many" 6 "B-cells: 6.6;granulocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (2.71e-2)" "unprognostic (1.39e-2)" "unprognostic (7.76e-2)" "unprognostic (1.68e-1)" "unprognostic (8.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.05e-2)" "unprognostic (9.69e-2)" "unprognostic (1.96e-2)" "unprognostic (4.04e-6)" "unprognostic (8.82e-2)" "unprognostic (1.28e-1)" "unprognostic (4.21e-1)" "unprognostic (4.65e-1)" 1.3 0.1 0.1 22.3 0.1 0.4 0.4 0.1 0.1 0.2 0.3 0.1 0.1 0.0 0.9 0.1 0.1 0.2 0.3 0.4 0.1 0.0 0.2 0.1 0.5 15.5 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.1 1.8 0.1 1.1 0.5 3.9 0.1 0.1 1.7 0.2 0.2 0.1 0.6 0.3 0.1 12.2 0.1 0.7 6.6 0.7 1.6 0.7 0.5 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 48.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.6 7.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 40.4 0.0 0.1 0.0 1.0 0.7 0.4 0.4 0.3 0.2 4.3 0.4 0.2 0.4 6.6 0.4 0.4 1.6 0.5 0.4 0.7 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 AK3 "AK3L1, AK6, AKL3L1" ENSG00000147853 "Adenylate kinase 3" Q9UIJ7 9 4709559-4742043 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 85.0;HEL: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063324 Enhanced Supported Mitochondria 68000 Mitochondria "HPA063324: " "unprognostic (1.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (6.55e-2)" "unprognostic (1.02e-1)" "unprognostic (2.21e-3)" "unprognostic (6.44e-2)" "unprognostic (2.81e-2)" "unprognostic (9.81e-3)" "unprognostic (1.90e-1)" "unprognostic (2.76e-2)" "prognostic favourable (6.07e-9)" "unprognostic (1.24e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.55e-3)" 24.6 25.1 20.9 9.8 22.4 6.8 24.0 14.6 17.5 17.7 23.7 15.3 16.0 24.4 18.9 17.5 28.3 14.0 16.1 90.0 22.4 16.4 37.7 75.1 16.4 13.1 25.2 15.2 22.4 15.7 16.9 14.1 13.0 22.9 19.0 23.0 17.4 14.5 19.1 72.0 18.1 22.0 21.2 24.1 12.1 22.5 9.3 24.9 15.2 20.8 32.8 14.9 20.1 17.1 7.0 14.4 17.0 5.6 14.7 17.1 10.2 8.7 7.3 12.5 5.1 17.5 12.9 0.9 11.0 26.0 6.9 10.4 1.2 9.7 8.1 3.8 14.0 5.6 9.1 10.6 11.8 85.0 6.9 54.4 13.0 22.0 13.8 5.7 2.8 20.4 9.5 5.9 8.2 20.3 4.1 11.1 20.7 5.2 5.5 16.5 11.2 2.7 7.4 4.5 4.0 20.2 12.2 20.7 13.0 12.9 4.2 7.4 5.8 11.4 12.6 5.8 5.9 15.2 8.6 2.8 1.8 10.0 10.6 4.3 4.1 6.8 5.6 17.0 16.2 4.4 14.7 7.0 12.5 14.8 10.5 6.9 16.6 17.1 1.9 14.7 3.4 14.4 16.7 10.2 20.9 22.4 14.6 17.5 22.4 16.4 25.2 15.2 22.9 24.9 AK5 ENSG00000154027 "Adenylate kinase 5" Q9Y6K8 1 77282051-77559969 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 95.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 29.7;BJ: 20.3;fHDF/TERT166: 23.1;LHCN-M2: 58.2;U-2 OS: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 10.9;naive CD4 T-cell: 14.2" "Group enriched" "Detected in many" 15 "dendritic cells: 10.9;T-cells: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019128, HPA057255" Enhanced Supported "Centriolar satellite,Cytosol" Cytosol "Centriolar satellite" "HPA019128: AB_1844682, HPA057255: " "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (1.13e-1)" "unprognostic (2.85e-2)" "unprognostic (1.03e-1)" "unprognostic (6.04e-2)" "unprognostic (2.20e-1)" "unprognostic (2.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.91e-2)" "prognostic favourable (3.88e-4)" "unprognostic (3.56e-3)" "unprognostic (6.17e-4)" "unprognostic (1.18e-1)" "unprognostic (5.96e-2)" "unprognostic (6.76e-2)" 1.8 2.1 43.8 1.9 35.7 3.7 14.1 1.3 95.5 2.0 1.8 20.4 0.0 1.8 1.6 1.5 1.8 1.8 1.7 1.5 35.8 11.8 2.0 1.2 1.4 2.5 13.0 41.1 1.5 2.1 2.4 1.4 1.8 11.4 2.7 1.8 0.0 3.1 2.7 1.3 2.4 1.7 1.7 14.2 2.4 2.9 7.3 13.9 0.0 1.7 0.0 2.1 1.5 0.4 0.8 10.9 0.7 0.7 0.1 14.2 1.9 0.0 1.1 0.8 0.0 10.9 29.7 0.4 20.3 4.3 3.3 1.4 0.1 0.5 0.1 0.1 23.1 0.1 0.0 0.0 1.7 0.7 0.2 0.1 0.1 0.0 0.5 0.1 0.0 3.6 0.1 0.6 1.3 9.5 0.2 0.2 58.2 0.2 0.0 0.1 1.1 7.4 0.5 2.1 0.3 9.0 0.3 4.5 1.1 0.0 0.0 1.2 0.1 0.1 2.3 8.0 18.2 0.4 0.6 4.7 4.2 0.0 1.6 1.0 2.9 0.7 0.7 0.0 3.4 0.1 0.5 0.8 3.2 1.6 10.9 0.8 14.2 7.8 0.5 0.1 0.2 1.2 1.4 1.9 43.8 35.7 1.3 47.1 35.8 11.8 13.0 41.1 11.4 13.9 AK9 "AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1, FLJ25791, FLJ42177, MGC26954" ENSG00000155085 "Adenylate kinase 9" Q5TCS8 6 109492856-109691217 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA030804, HPA030805, HPA031779, HPA031781, HPA036324, HPA036711" Enhanced Enhanced "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA030804: , HPA030805: , HPA031779: AB_10603674, HPA031781: , HPA036324: , HPA036711: " "unprognostic (9.68e-3)" "unprognostic (2.15e-1)" "unprognostic (1.66e-2)" "unprognostic (2.36e-2)" "unprognostic (3.42e-1)" "unprognostic (7.28e-2)" "unprognostic (1.41e-3)" "unprognostic (6.76e-3)" "unprognostic (1.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-4)" "unprognostic (2.58e-1)" "unprognostic (2.98e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (8.39e-2)" "unprognostic (5.56e-2)" 4.6 4.7 7.7 5.6 8.4 4.7 8.3 13.5 8.7 5.0 6.5 8.5 4.1 5.0 6.3 11.1 6.2 11.3 5.2 6.9 9.1 10.3 7.6 4.5 6.7 5.5 9.4 4.9 6.7 4.6 15.4 33.3 4.4 11.5 5.9 6.7 3.7 7.0 6.3 6.1 5.5 6.2 5.7 11.7 6.5 6.1 22.0 7.7 20.5 11.4 4.1 5.0 5.9 4.4 11.2 2.9 15.1 4.1 4.9 6.4 1.6 2.6 1.8 7.7 13.7 7.2 4.5 5.7 4.0 5.0 4.2 5.8 2.9 5.3 5.6 2.1 3.8 4.6 2.2 4.4 9.0 11.9 4.8 4.2 4.5 2.9 5.9 5.3 2.6 3.6 8.5 7.8 10.2 5.5 4.0 4.7 3.1 5.3 4.6 3.6 1.7 2.9 6.1 4.3 5.2 6.2 5.1 9.4 8.0 4.9 4.7 6.7 6.0 6.5 5.9 4.1 2.7 5.9 2.6 2.5 2.1 3.3 8.2 6.7 2.2 15.1 2.8 6.5 5.1 1.5 4.4 10.5 5.1 6.1 2.0 11.2 6.4 5.5 5.4 4.9 4.1 2.9 3.6 1.6 7.7 8.4 13.5 8.7 9.1 10.3 9.4 4.9 11.5 7.7 ATRIP "FLJ12343, MGC20625, MGC21482, MGC26740" ENSG00000164053 "ATR interacting protein" Q8WXE1 3 48446710-48467645 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.3" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033109, HPA047590" Approved Supported Nucleoplasm Nucleoplasm "CAB033109: AB_634993, HPA047590: " "unprognostic (5.43e-3)" "unprognostic (1.29e-1)" "unprognostic (2.85e-1)" "unprognostic (8.87e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "unprognostic (4.72e-2)" "unprognostic (8.88e-3)" "unprognostic (2.66e-1)" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (7.05e-2)" "unprognostic (2.01e-1)" "unprognostic (8.89e-2)" "unprognostic (2.59e-1)" "unprognostic (1.40e-2)" "unprognostic (8.52e-2)" 6.1 5.3 4.9 6.2 5.5 7.1 6.5 9.4 6.4 7.0 5.2 7.2 5.1 3.8 8.2 5.1 7.0 5.7 5.0 5.4 3.5 2.8 5.4 5.4 6.0 5.5 4.8 3.6 6.8 5.3 5.3 5.5 9.2 3.8 6.2 6.0 6.5 5.1 7.2 7.3 8.0 4.6 5.4 3.4 6.3 5.2 38.3 4.6 13.4 9.3 6.6 9.0 5.5 6.2 0.9 2.9 1.0 1.4 1.4 3.4 1.5 6.9 2.9 8.1 6.1 5.0 8.4 8.6 10.6 5.0 13.2 11.0 4.2 4.9 15.5 5.0 4.5 7.3 9.1 8.4 12.9 9.2 4.6 12.1 12.9 2.9 2.7 11.7 7.8 3.5 2.6 7.1 3.4 5.8 9.6 8.1 12.3 3.9 9.8 4.1 6.3 8.7 6.6 7.4 11.4 4.4 3.5 4.0 5.8 8.5 8.7 3.4 7.3 4.5 6.4 8.8 5.8 10.5 12.3 9.5 15.1 10.7 4.6 8.8 4.9 0.7 1.4 0.0 3.3 0.8 0.5 0.9 3.0 1.7 0.9 0.5 2.1 3.3 1.0 1.4 1.0 2.9 3.4 1.5 4.9 5.5 9.4 6.4 3.5 2.8 4.8 3.6 3.8 4.6 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991717-79009867 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced 2300000 "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavourable (1.41e-4)" "prognostic unfavourable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavourable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 13.8 15.3 9.6 13.1 10.2 8.1 13.0 12.2 10.8 17.7 43.8 12.3 25.4 25.5 12.0 14.3 27.5 10.0 19.5 10.8 9.0 6.9 10.3 17.7 11.1 11.5 12.5 7.7 10.4 14.7 13.1 11.8 33.0 12.0 36.7 41.5 7.9 30.3 41.4 9.0 8.9 27.2 8.0 12.4 18.1 25.8 19.0 10.3 14.1 12.4 8.9 14.4 10.3 13.7 4.1 3.8 17.5 4.4 3.1 6.2 4.4 26.4 29.0 8.1 11.7 7.7 9.2 10.4 16.3 14.3 17.6 14.9 13.7 25.0 6.4 9.6 11.4 13.4 6.9 12.9 17.6 10.6 12.6 8.3 8.8 11.4 6.6 7.9 13.1 9.5 8.3 16.2 8.8 30.3 10.4 10.9 11.7 14.3 12.0 4.7 5.5 30.9 6.7 13.3 7.2 7.7 13.3 11.7 11.7 8.7 57.8 12.3 71.4 9.5 15.1 26.3 23.8 11.8 20.4 12.9 10.7 6.2 16.8 6.1 16.4 6.1 3.8 8.1 6.2 4.4 6.1 4.1 4.6 5.2 3.8 2.9 4.5 4.4 17.5 3.1 2.9 2.7 3.8 4.4 9.6 10.2 12.2 10.8 9.0 6.9 12.5 7.7 12.0 10.3 CMPK1 "CMPK, UMP-CMPK" ENSG00000162368 "Cytidine/uridine monophosphate kinase 1" P30085 1 47333797-47378839 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053730, HPA058604" Approved Supported Nucleoplasm "Intracellular and membrane" 2100000 Nucleoplasm "HPA053730: AB_2682244, HPA058604: AB_2683773" "unprognostic (2.16e-2)" "unprognostic (1.16e-1)" "unprognostic (9.39e-3)" "unprognostic (1.18e-1)" "unprognostic (1.09e-3)" "unprognostic (1.50e-2)" "unprognostic (1.59e-2)" "unprognostic (9.88e-2)" "unprognostic (5.80e-2)" "unprognostic (2.90e-2)" "unprognostic (1.71e-2)" "unprognostic (2.61e-1)" "unprognostic (1.28e-2)" "unprognostic (2.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-3)" "unprognostic (7.36e-2)" 35.0 17.0 28.5 30.4 24.4 14.8 72.2 18.0 35.8 26.8 44.8 17.8 20.9 53.7 16.5 19.3 42.2 13.5 39.2 28.6 28.0 31.4 26.2 88.2 36.8 46.2 35.1 16.8 16.2 42.3 19.3 16.6 16.0 25.4 32.8 48.1 16.2 50.8 18.3 30.4 22.2 64.9 46.9 33.1 21.6 35.9 8.6 18.2 25.6 31.7 26.7 28.0 34.0 39.0 11.2 10.6 23.1 12.4 15.0 17.5 12.1 30.3 17.0 22.0 19.7 40.3 47.2 31.3 54.1 32.6 32.9 33.5 15.1 21.1 45.0 27.9 36.7 20.7 16.3 28.0 45.1 68.1 13.3 35.0 23.5 26.1 26.3 49.8 25.6 26.4 33.9 27.4 30.8 34.0 32.9 36.4 42.8 11.1 40.4 23.5 14.0 23.6 25.2 38.2 33.8 32.0 33.5 20.0 10.6 38.7 45.0 31.0 11.2 29.8 31.8 41.2 23.8 39.3 44.4 26.5 36.6 30.7 32.5 30.9 28.1 23.1 10.2 18.2 13.6 10.7 17.5 11.2 15.5 16.7 10.6 10.2 14.7 14.0 4.2 15.0 12.4 8.9 16.0 12.1 28.5 24.4 18.0 35.8 28.0 31.4 35.1 16.8 25.4 18.2 CMPK2 "NDK, TYKi, UMP-CMPK2" ENSG00000134326 "Cytidine/uridine monophosphate kinase 2" Q5EBM0 2 6840570-6866635 "Enzymes, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 13.9;BJ hTERT+ SV40 Large T+ RasG12V: 12.7;HEL: 19.7;MOLT-4: 10.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041430 Approved Approved Mitochondria Mitochondria "HPA041430: AB_10796674" "unprognostic (2.37e-1)" "unprognostic (6.07e-2)" "unprognostic (5.71e-2)" "prognostic unfavourable (4.71e-4)" "unprognostic (1.82e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-2)" "unprognostic (8.93e-2)" "unprognostic (6.63e-2)" "unprognostic (4.54e-3)" "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (1.09e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (7.69e-2)" "unprognostic (4.32e-2)" 8.8 3.8 3.0 6.8 8.1 14.5 4.2 0.9 5.0 2.7 4.2 4.0 1.3 5.0 2.5 6.4 1.8 2.3 3.4 3.7 3.3 3.9 4.0 3.1 17.9 13.4 3.2 5.7 1.3 3.7 2.9 3.0 4.7 3.6 2.1 2.2 4.7 20.8 4.3 3.0 1.2 6.1 3.1 3.8 7.9 7.4 9.2 0.4 8.8 3.1 1.6 2.6 2.7 1.6 1.4 1.9 7.8 6.4 0.9 0.7 1.2 0.2 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.2 13.9 12.7 0.0 1.4 3.1 0.8 0.0 0.2 0.0 0.0 0.0 0.3 0.2 19.7 0.0 0.0 0.0 0.6 1.4 0.0 0.0 0.1 0.0 0.0 4.8 0.1 0.0 0.1 10.8 3.6 0.3 1.0 3.4 0.0 0.0 0.0 0.4 0.3 0.5 0.2 0.0 1.7 0.0 1.3 0.0 0.0 0.2 0.0 0.0 3.3 0.4 0.0 0.0 3.6 0.8 5.5 2.8 7.8 0.7 6.4 0.4 1.4 0.5 0.4 1.9 0.2 0.5 0.5 1.8 0.9 3.2 0.1 0.6 1.2 3.0 8.1 0.9 5.0 3.3 3.9 3.2 5.7 3.6 0.4 DCK ENSG00000156136 "Deoxycytidine kinase" P27707 4 70992538-71030914 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 80.9" "Cell line enhanced" "Detected in all" "Daudi: 59.7;U-698: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059609, HPA062773" Enhanced Supported Nucleoplasm Nucleoplasm "HPA059609: , HPA062773: " "unprognostic (9.16e-2)" "unprognostic (2.44e-1)" "unprognostic (5.24e-3)" "unprognostic (4.77e-2)" "unprognostic (3.95e-1)" "unprognostic (6.45e-2)" "prognostic unfavourable (6.90e-7)" "unprognostic (3.04e-2)" "unprognostic (7.19e-2)" "unprognostic (8.28e-2)" "unprognostic (4.51e-1)" "unprognostic (1.33e-1)" "unprognostic (3.37e-2)" "unprognostic (4.47e-2)" "unprognostic (6.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.27e-2)" 8.0 8.3 11.9 30.9 16.8 17.2 6.9 11.4 14.8 5.6 8.6 10.4 2.6 7.6 7.5 4.4 8.8 5.5 6.1 5.5 12.3 13.1 5.8 4.8 9.7 42.8 11.7 10.3 6.0 5.0 3.6 4.2 7.9 11.1 5.9 10.4 6.4 6.3 4.0 6.8 7.9 12.4 7.5 17.6 17.5 8.2 5.6 8.6 80.9 8.3 3.8 39.9 9.5 6.5 27.9 34.2 17.5 12.7 18.5 24.9 25.1 6.6 4.4 9.7 5.7 3.0 5.3 5.6 17.2 6.4 13.6 11.4 2.9 14.5 59.7 7.4 7.1 3.9 8.6 5.4 18.4 12.6 5.3 12.3 5.1 4.5 3.1 24.6 15.9 2.7 6.6 8.3 5.0 7.7 4.9 22.7 15.5 3.8 30.4 9.7 4.7 5.4 25.8 19.7 4.7 6.8 4.6 8.6 9.2 6.4 12.7 7.5 5.7 12.9 6.2 15.4 11.6 12.9 9.2 8.6 5.6 48.4 10.7 15.4 11.4 13.1 10.7 17.5 16.2 12.7 20.3 27.9 21.8 20.0 14.3 26.4 23.4 23.5 5.4 18.5 12.1 34.2 24.9 25.1 11.9 16.8 11.4 14.8 12.3 13.1 11.7 10.3 11.1 8.6 DCTD ENSG00000129187 "DCMP deaminase" P32321 4 182890060-182917936 "Enzymes, Predicted intracellular proteins" "Nucleotide biosynthesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035894 Approved Approved Nucleoplasm,Cytosol 13000 "Nucleoplasm, Cytosol" "HPA035894: AB_10673488" "unprognostic (1.26e-1)" "unprognostic (9.80e-3)" "unprognostic (3.15e-2)" "unprognostic (3.78e-3)" "unprognostic (3.13e-3)" "unprognostic (2.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.59e-3)" "unprognostic (2.62e-2)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.20e-1)" "prognostic favourable (1.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.59e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-1)" 24.8 46.2 24.7 19.9 23.8 12.9 27.3 11.6 28.3 27.1 20.4 17.3 22.6 16.4 26.0 20.1 30.9 25.9 40.9 25.8 22.5 22.2 25.7 47.6 25.8 29.4 21.1 20.3 35.9 51.7 28.3 25.3 18.9 21.3 23.7 21.5 30.0 26.4 22.8 24.8 19.4 19.1 27.4 25.6 24.9 27.2 11.8 16.7 15.0 52.9 21.3 26.0 24.5 25.1 31.9 24.8 23.7 25.7 30.8 36.8 22.7 22.4 20.7 21.2 19.5 32.0 43.7 27.7 43.3 38.7 31.1 19.3 21.0 43.7 7.8 10.7 42.2 11.2 15.4 27.0 28.6 37.8 11.7 36.1 12.0 25.0 34.3 35.1 22.6 36.3 28.9 27.3 28.5 26.6 35.8 78.2 41.3 16.3 22.7 21.5 16.8 18.1 24.8 15.1 15.1 25.0 27.0 20.9 13.0 20.5 17.7 20.2 13.6 18.4 30.9 25.9 19.9 12.5 33.0 30.1 16.2 10.0 28.6 23.0 30.4 23.7 22.0 19.7 29.2 25.7 36.8 31.9 25.6 29.7 24.8 21.7 25.5 26.7 1.6 30.8 24.9 19.1 21.9 22.7 24.7 23.8 11.6 28.3 22.5 22.2 21.1 20.3 21.3 16.7 DCTPP1 "CDA03, MGC5627, RS21C6, XTP3TPA" ENSG00000179958 "DCTP pyrophosphatase 1" Q9H773 16 30423619-30430075 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002832 Uncertain Approved Nucleoplasm,Cytosol 270000 "Nucleoplasm, Cytosol" "HPA002832: AB_1080615" "prognostic unfavourable (1.64e-5)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (4.09e-2)" "prognostic unfavourable (6.28e-4)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (4.35e-2)" "unprognostic (2.43e-2)" "unprognostic (3.65e-2)" "prognostic favourable (9.71e-9)" "unprognostic (1.10e-3)" "unprognostic (8.78e-3)" "unprognostic (1.10e-2)" "unprognostic (2.53e-1)" 15.3 15.8 14.8 25.0 13.2 12.5 20.7 15.5 19.2 12.1 37.4 10.3 11.3 20.7 14.1 14.4 19.7 18.9 28.1 23.3 12.1 12.6 27.0 25.3 11.2 27.6 13.3 16.6 16.6 25.2 16.4 7.7 16.3 11.4 15.4 40.3 10.6 20.5 21.1 28.3 16.1 22.9 13.9 11.3 22.5 16.4 9.9 7.8 21.3 22.6 26.0 25.0 13.2 13.0 47.3 30.9 19.0 24.5 23.1 26.2 25.3 26.3 32.4 14.8 19.0 4.2 5.7 13.7 12.7 7.6 19.2 19.6 24.3 22.5 35.7 26.7 7.9 20.7 30.6 24.9 24.0 18.8 48.3 20.8 14.9 31.6 5.4 37.1 32.4 6.5 14.2 21.4 12.3 19.7 26.1 12.6 13.6 46.0 44.1 41.6 19.5 26.2 62.6 16.4 46.5 22.2 17.2 31.5 17.8 8.4 30.2 11.9 26.1 16.0 9.9 14.9 13.3 19.1 22.8 8.3 24.7 45.5 9.8 30.8 17.3 19.0 12.4 11.7 18.8 22.1 26.2 47.3 24.2 21.3 28.7 40.2 21.8 21.0 1.5 23.1 24.5 30.9 24.1 25.3 14.8 13.2 15.5 19.2 12.1 12.6 13.3 16.6 11.4 7.8 DGUOK dGK ENSG00000114956 "Deoxyguanosine kinase" Q16854 2 73926826-73958961 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034766, HPA057246" Approved "HPA034766: AB_10669850, HPA057246: " "unprognostic (3.40e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-2)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (4.17e-2)" "unprognostic (2.14e-2)" "unprognostic (1.37e-2)" "unprognostic (4.10e-3)" "unprognostic (5.07e-2)" "unprognostic (1.41e-1)" "unprognostic (9.84e-2)" "prognostic unfavourable (8.69e-7)" "unprognostic (3.86e-1)" "unprognostic (2.21e-2)" "unprognostic (5.98e-2)" "prognostic favourable (7.47e-4)" 23.8 34.8 25.8 26.2 32.3 26.3 33.7 18.4 33.7 26.1 28.0 23.6 24.9 19.4 30.7 40.9 26.6 35.4 28.0 24.5 28.3 26.5 26.7 31.7 24.7 37.2 23.5 22.6 35.5 20.9 11.2 39.9 30.6 27.1 28.6 34.1 25.2 22.5 28.2 14.1 29.2 29.3 25.8 23.5 33.1 23.6 34.3 17.9 41.7 29.0 21.8 44.2 27.2 27.4 43.5 36.4 50.5 31.4 30.0 42.3 31.3 15.7 26.9 27.9 24.8 18.1 19.9 13.7 10.5 21.2 25.4 23.6 34.0 19.1 29.8 10.1 15.5 12.5 31.7 20.5 30.5 16.3 19.1 23.4 10.2 38.4 26.7 21.4 23.8 18.7 19.4 18.6 21.9 17.9 23.8 13.7 29.1 19.2 20.1 37.8 28.3 19.7 25.9 28.0 19.8 20.2 18.4 32.1 31.4 10.3 10.1 27.1 12.2 12.2 16.8 16.3 26.2 14.1 19.0 11.2 10.8 30.0 23.5 23.2 34.6 41.3 27.4 50.5 25.3 31.4 29.8 40.6 31.4 27.9 32.4 43.5 42.3 33.1 22.5 30.0 30.8 36.4 29.3 31.3 25.8 32.3 18.4 33.7 28.3 26.5 23.5 22.6 27.1 17.9 DNM1 DNM ENSG00000106976 "Dynamin 1" Q05193 9 128191655-128255248 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 133.5" "Cell line enhanced" "Detected in many" "A549: 48.8;U-87 MG: 18.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005920, HPA049910, HPA061801" Enhanced Supported Nucleoplasm 440000 Nucleoplasm "CAB005920: , HPA049910: , HPA061801: " "unprognostic (3.25e-2)" "unprognostic (5.49e-2)" "unprognostic (1.34e-3)" "unprognostic (3.95e-2)" "unprognostic (4.57e-2)" "unprognostic (1.16e-1)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (5.53e-2)" "unprognostic (6.53e-2)" "unprognostic (6.62e-3)" "unprognostic (6.30e-1)" "unprognostic (9.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (3.07e-3)" "unprognostic (1.10e-3)" 5.9 6.1 31.5 3.3 36.9 2.3 4.6 57.7 133.5 11.7 3.0 2.5 0.0 2.4 4.6 2.7 3.3 6.3 9.0 2.7 33.4 24.0 2.9 1.8 2.5 2.5 18.3 33.0 1.6 4.7 3.2 5.5 2.7 33.0 2.9 2.9 4.3 2.6 3.1 2.3 4.6 3.3 4.4 5.1 1.6 2.6 4.0 1.8 0.0 1.9 0.4 2.3 3.6 3.7 0.3 0.4 0.5 0.3 0.0 0.3 0.7 3.2 48.8 4.4 1.0 1.4 14.9 0.2 3.0 7.3 6.2 2.6 0.6 1.0 0.0 4.2 6.3 5.8 0.7 0.3 3.4 0.0 4.7 3.1 7.0 0.2 1.0 0.4 2.2 3.9 0.1 4.8 0.0 0.0 1.1 0.2 0.0 1.3 0.2 1.0 4.7 8.9 5.8 0.1 1.5 0.9 0.0 6.3 10.6 10.4 0.3 0.4 0.1 4.2 0.2 0.2 14.1 14.2 6.2 0.4 0.1 0.3 18.6 0.1 1.0 0.0 0.3 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.4 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.7 31.5 36.9 57.7 71.8 33.4 24.0 18.3 33.0 33.0 1.8 DNM1L "DRP1, DVLP, DYMPLE, HDYNIV, VPS1" ENSG00000087470 "Dynamin 1 like" O00429 12 32679200-32745650 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Endocytosis, Necrosis" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009952, HPA039324" Supported Enhanced Vesicles,Cytosol 10000000 Cytosol Vesicles "CAB009952: AB_2093533, HPA039324: " "unprognostic (2.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (5.09e-1)" "unprognostic (4.06e-2)" "prognostic unfavourable (6.27e-6)" "unprognostic (8.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.04e-2)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (7.48e-2)" "unprognostic (1.57e-2)" 15.4 16.2 24.9 14.8 34.4 22.3 14.3 40.5 37.8 13.0 14.5 12.4 14.9 12.3 16.5 16.5 19.8 13.3 11.9 25.4 26.1 28.1 19.4 12.8 11.2 13.8 23.4 23.2 14.1 9.8 28.7 18.8 16.0 27.9 19.3 16.0 12.1 11.1 21.1 25.6 11.8 11.0 21.7 21.7 11.6 12.2 23.1 14.9 13.4 15.2 17.4 15.8 16.9 12.2 5.9 17.0 5.0 14.6 7.2 7.9 7.1 22.1 22.1 23.2 23.8 18.8 19.3 44.9 24.9 19.2 23.5 21.8 31.0 17.0 29.8 17.5 22.5 19.9 24.4 28.6 28.3 15.7 19.9 33.9 21.3 17.0 15.5 24.0 17.9 17.4 14.5 24.9 25.7 28.4 24.5 12.9 26.9 8.6 9.6 20.2 48.9 10.8 16.2 43.7 20.3 19.8 30.5 20.3 20.8 26.5 18.2 19.4 20.9 16.4 25.6 20.1 20.2 47.1 23.1 9.1 24.6 31.1 19.5 16.1 15.2 5.0 9.7 3.1 5.6 14.6 6.8 5.9 6.0 5.9 17.0 5.2 7.3 7.9 1.7 7.2 13.6 5.4 6.1 7.1 24.9 34.4 40.5 37.8 26.1 28.1 23.4 23.2 27.9 14.9 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" 500000 "Golgi apparatus, Cytosol" "HPA054246: " "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favourable (8.91e-4)" "prognostic unfavourable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 23.8 32.6 18.5 29.3 31.2 53.4 20.4 25.7 29.7 20.1 51.4 57.5 46.0 32.1 20.4 16.8 29.9 19.7 27.0 35.0 20.8 18.0 38.5 25.1 39.2 28.2 48.3 18.0 17.9 32.2 19.5 20.0 32.3 32.2 24.0 42.5 24.5 24.7 37.7 46.6 40.6 50.8 18.6 43.1 37.6 48.2 23.3 36.4 39.1 23.5 21.1 41.5 35.7 31.5 3.4 11.1 8.6 9.8 10.1 5.8 4.6 34.9 28.9 21.2 16.9 21.9 21.5 27.2 23.4 22.2 34.7 29.5 28.8 23.1 25.4 42.2 25.2 30.7 28.9 25.4 29.1 31.1 23.0 48.7 25.8 32.2 27.0 26.7 46.3 22.0 19.6 26.5 25.0 33.7 39.1 43.7 21.3 42.3 37.2 25.5 24.1 35.0 37.8 23.0 28.6 22.8 52.7 30.6 20.0 26.7 22.9 16.7 18.4 31.8 30.5 38.1 12.9 53.5 30.9 36.2 36.9 23.4 28.5 40.9 18.8 3.0 4.5 8.6 5.6 8.2 5.1 3.4 4.2 5.8 5.3 3.1 2.4 4.1 8.5 10.1 9.8 11.1 4.8 4.6 18.5 31.2 25.7 29.7 20.8 18.0 48.3 18.0 32.2 36.4 DNM3 KIAA0820 ENSG00000197959 "Dynamin 3" Q9UQ16 1 171841498-172418466 "Enzymes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.3" "Cell line enhanced" "Detected in many" "HEL: 17.9;HMC-1: 8.3;RH-30: 8.1;RPTEC TERT1: 15.5;U-251 MG: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 4.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064121 Approved "Golgi apparatus" "Golgi apparatus" "HPA064121: " "unprognostic (8.21e-2)" "unprognostic (6.80e-3)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (8.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.52e-3)" "unprognostic (6.46e-2)" "unprognostic (5.52e-2)" "unprognostic (2.96e-2)" "unprognostic (2.45e-2)" "unprognostic (3.37e-1)" "unprognostic (6.10e-4)" "unprognostic (1.60e-3)" "unprognostic (1.35e-1)" "unprognostic (2.22e-1)" "unprognostic (2.70e-3)" 5.0 19.3 14.1 2.3 28.3 2.6 3.4 41.4 39.7 6.8 2.7 26.8 0.0 1.9 5.9 3.1 3.0 6.0 5.1 3.0 14.3 16.3 5.8 1.4 7.5 2.5 19.6 17.7 4.6 2.6 3.5 10.3 1.6 47.3 3.6 2.7 2.9 3.7 3.6 2.5 4.0 2.4 5.7 16.4 3.6 5.3 5.4 22.1 0.0 3.4 0.0 2.2 4.3 3.6 0.7 0.7 1.1 0.4 1.0 4.0 3.8 0.6 2.0 1.6 0.3 1.2 0.8 0.0 0.4 1.0 0.8 1.0 0.0 2.9 0.0 6.2 0.9 0.2 1.2 2.3 0.7 0.8 2.3 17.9 3.0 0.0 0.1 0.3 8.3 0.6 0.4 0.9 0.5 0.4 0.0 0.2 0.3 0.0 1.1 0.1 4.7 1.4 1.1 8.1 0.0 15.5 0.1 3.2 0.6 2.1 0.6 0.2 0.0 0.7 0.2 2.3 3.1 1.9 11.1 3.1 0.5 0.1 2.2 0.9 0.8 0.0 0.4 0.0 0.7 0.0 0.9 0.7 1.0 0.5 0.7 0.0 1.2 1.5 1.1 1.0 0.3 0.0 4.0 3.8 14.1 28.3 41.4 31.6 14.3 16.3 19.6 17.7 47.3 22.1 DTYMK "CDC8, TMPK, TYMK" ENSG00000168393 "Deoxythymidylate kinase" P23919 2 241675742-241686991 "Enzymes, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042593, HPA042719" Approved Approved Mitochondria Mitochondria "HPA042593: AB_10959590, HPA042719: AB_10960633" "unprognostic (1.90e-1)" "unprognostic (6.95e-2)" "unprognostic (4.14e-1)" "unprognostic (8.61e-2)" "unprognostic (1.89e-1)" "unprognostic (9.45e-2)" "prognostic unfavourable (1.73e-5)" "unprognostic (1.44e-2)" "unprognostic (2.64e-2)" "unprognostic (5.50e-2)" "unprognostic (2.60e-2)" "unprognostic (6.94e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (7.13e-2)" "unprognostic (6.81e-2)" "unprognostic (5.07e-2)" "unprognostic (9.19e-2)" 12.4 17.6 11.6 17.3 15.0 29.1 14.4 14.5 12.4 10.0 13.8 16.5 9.3 12.0 12.4 9.7 20.0 9.7 10.2 9.4 9.0 6.5 15.5 19.5 10.5 21.0 14.0 9.5 9.5 13.6 5.0 8.8 10.4 11.8 11.5 11.7 10.8 9.6 10.0 6.7 17.9 13.0 13.0 9.5 18.8 13.5 11.1 15.1 20.7 9.4 16.1 17.9 11.7 11.9 19.8 21.1 12.0 24.7 15.7 21.8 15.7 25.2 27.9 24.2 30.8 8.0 8.7 25.7 20.7 15.6 27.5 32.5 12.7 30.6 12.2 6.4 16.7 21.3 22.3 25.1 14.8 28.8 26.5 26.2 23.4 24.1 6.6 16.6 21.7 6.1 6.8 26.6 10.8 26.4 29.4 10.3 29.2 26.3 30.6 28.8 23.9 23.5 26.2 35.7 17.0 15.9 14.6 29.3 18.3 13.4 20.7 16.5 18.8 29.7 17.1 40.2 28.9 25.6 38.1 11.6 12.2 34.3 32.2 26.6 46.7 12.0 14.9 9.5 17.4 24.7 16.8 19.2 16.1 18.2 10.5 19.8 16.0 14.7 2.5 15.7 18.8 21.1 21.8 15.7 11.6 15.0 14.5 12.4 9.0 6.5 14.0 9.5 11.8 15.1 DUT dUTPase ENSG00000128951 "Deoxyuridine triphosphatase" P33316 15 48331011-48343373 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054422, HPA060360" Enhanced Supported Nucleoplasm Nucleoplasm "HPA054422: , HPA060360: " "unprognostic (1.82e-1)" "unprognostic (3.49e-2)" "unprognostic (7.89e-2)" "unprognostic (5.27e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (4.42e-3)" "unprognostic (1.87e-2)" "unprognostic (4.25e-1)" "unprognostic (3.54e-2)" "unprognostic (3.68e-2)" "unprognostic (4.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-2)" "unprognostic (1.71e-2)" 26.9 32.9 23.2 51.1 31.8 69.0 31.9 31.7 27.6 26.8 26.3 24.4 27.2 14.5 29.8 31.8 33.7 26.9 28.2 35.5 23.2 26.5 25.4 19.8 25.7 44.7 25.3 23.6 33.4 22.2 23.7 30.7 26.0 22.5 30.3 24.3 28.1 27.5 26.1 25.6 27.3 22.6 25.6 23.9 30.1 25.8 31.9 20.7 120.3 40.5 37.7 43.2 23.5 28.4 34.5 32.3 17.0 24.5 22.2 40.2 24.3 25.6 8.1 19.7 18.7 13.8 14.8 11.7 27.2 17.4 25.2 31.3 9.3 17.7 71.6 14.7 14.9 35.3 20.6 18.6 24.7 50.4 21.3 58.4 21.3 12.6 7.7 61.2 27.8 9.0 12.7 17.0 9.0 16.7 31.6 40.7 18.5 10.4 54.7 72.1 12.4 15.6 44.6 43.2 75.2 16.5 17.4 28.6 29.1 20.2 16.4 23.3 23.1 48.9 13.8 26.4 25.5 31.4 35.7 32.9 68.3 70.5 20.0 105.1 28.9 11.3 19.5 17.0 21.7 19.3 28.1 34.5 38.9 34.2 28.2 31.6 40.2 26.5 11.1 22.2 24.5 32.3 34.4 24.3 23.2 31.8 31.7 27.6 23.2 26.5 25.3 23.6 22.5 20.7 EEF1A1 "EE1A1, EEF1A, EF1A, LENG7" ENSG00000156508 "Eukaryotic translation elongation factor 1 alpha 1" P68104 6 73515750-73523797 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "Elongation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051759, HPA053862, HPA056990" Supported Supported Cytosol Cytosol "HPA051759: , HPA053862: , HPA056990: " "unprognostic (6.47e-2)" "unprognostic (7.86e-3)" "unprognostic (2.53e-2)" "unprognostic (9.64e-2)" "unprognostic (1.39e-2)" "unprognostic (1.08e-1)" "prognostic unfavourable (5.57e-4)" "unprognostic (3.13e-1)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (1.41e-1)" "unprognostic (3.47e-1)" "unprognostic (8.61e-2)" "unprognostic (1.65e-1)" "unprognostic (8.00e-2)" "unprognostic (2.04e-1)" "unprognostic (7.73e-2)" 134.1 124.1 80.2 136.0 75.6 140.9 182.0 103.3 106.2 149.6 133.3 94.9 93.7 81.7 152.0 127.3 136.4 143.1 102.4 88.2 71.5 58.0 130.9 123.1 169.6 135.6 74.3 93.2 240.8 227.6 106.3 111.2 89.1 79.7 115.0 114.7 105.0 133.3 123.6 51.3 139.8 101.6 121.6 108.6 111.3 121.5 129.9 71.6 125.1 132.4 143.1 169.7 151.1 134.8 258.9 209.7 54.6 187.6 184.6 366.8 517.5 111.1 141.0 200.2 273.4 410.7 679.5 159.4 166.6 430.1 213.7 205.1 218.7 153.9 454.1 222.8 281.5 118.0 244.5 318.4 206.0 79.2 153.0 169.5 115.0 243.6 356.6 315.0 185.1 587.0 541.5 157.3 530.9 289.4 313.2 143.7 258.2 148.2 134.8 330.2 214.2 98.0 268.8 337.3 509.0 274.5 235.6 164.3 182.4 83.5 196.4 329.6 133.5 509.2 240.4 91.3 130.0 67.6 189.1 161.4 143.4 106.6 94.8 261.3 143.4 54.6 187.6 20.8 198.7 165.4 366.8 258.9 288.8 250.9 209.7 199.5 323.8 277.8 17.0 184.6 169.0 161.7 202.9 517.5 80.2 75.6 103.3 106.2 71.5 58.0 74.3 93.2 79.7 71.6 EEF1A2 "EEF1AL, HS1, STN, STNL" ENSG00000101210 "Eukaryotic translation elongation factor 1 alpha 2" Q05639 20 63488012-63499322 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Autism spectrum disorder, Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skeletal muscle: 298.6" "Cell line enhanced" "Detected in many" "HAP1: 55.3;HBF TERT88: 27.8;MCF7: 45.7;SCLC-21H: 29.1;T-47d: 23.7;U-2 OS: 32.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 9 "T-reg: 1.8" "Lineage enriched" "Detected in single" 9 "T-cells: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034019, HPA051759, HPA053862, HPA056990" Approved Supported Cytosol 55000000 Cytosol "CAB034019: AB_1562672, HPA051759: , HPA053862: , HPA056990: " "unprognostic (1.40e-2)" "unprognostic (6.82e-2)" "unprognostic (4.56e-2)" "prognostic unfavourable (2.90e-5)" "unprognostic (5.17e-2)" "prognostic unfavourable (9.11e-4)" "unprognostic (4.85e-1)" "unprognostic (1.68e-1)" "unprognostic (3.02e-2)" "unprognostic (1.74e-2)" "unprognostic (2.20e-2)" "unprognostic (2.30e-1)" "unprognostic (1.86e-1)" "unprognostic (8.29e-3)" "unprognostic (1.82e-1)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" 2.2 8.0 21.3 2.3 23.5 1.9 2.2 41.1 51.3 1.9 2.3 2.3 0.1 2.2 2.0 2.3 4.1 2.1 2.6 51.9 23.0 21.0 2.0 2.0 2.0 2.1 13.9 31.0 2.0 3.5 6.1 16.6 2.0 23.1 3.7 2.1 1.8 3.4 2.2 298.6 2.2 2.3 2.1 4.8 2.0 3.6 2.3 3.6 0.0 2.0 23.9 2.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.3 0.1 10.6 0.2 2.5 0.0 0.1 1.3 2.1 0.3 10.5 3.5 1.4 7.0 0.0 18.6 0.1 5.0 55.3 0.1 27.8 0.1 2.5 0.0 4.0 0.4 0.6 0.0 2.5 0.2 0.3 0.0 0.2 0.0 0.6 0.0 0.1 45.7 0.1 0.1 1.9 17.8 1.3 0.0 1.7 0.4 0.5 29.1 17.7 16.8 1.9 0.1 23.7 0.6 0.0 0.0 32.4 0.1 0.3 0.0 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.3 21.3 23.5 41.1 51.3 23.0 21.0 13.9 31.0 23.1 3.6 EEF2 "EEF-2, EF2" ENSG00000167658 "Eukaryotic translation elongation factor 2" P13639 19 3976056-3985469 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Cancer-related genes, Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007795, HPA040534, HPA057351" Enhanced Enhanced "Plasma membrane,Cytosol" 9700000 "Plasma membrane, Cytosol" "CAB007795: AB_598149, HPA040534: AB_2677024, HPA057351: AB_2683417" "unprognostic (5.47e-2)" "unprognostic (9.59e-2)" "unprognostic (3.75e-1)" "prognostic favourable (1.81e-6)" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.53e-2)" "unprognostic (2.11e-1)" "unprognostic (1.83e-1)" "unprognostic (1.77e-2)" "unprognostic (1.25e-2)" "unprognostic (1.42e-1)" "prognostic favourable (1.25e-5)" "unprognostic (4.46e-2)" "unprognostic (5.60e-2)" "unprognostic (6.82e-2)" "unprognostic (9.86e-2)" 104.2 84.9 64.0 66.7 57.1 92.7 77.5 55.7 96.2 93.4 91.3 55.8 80.8 95.4 100.1 75.1 115.1 83.4 88.6 104.1 51.6 44.4 65.5 161.0 67.7 108.9 51.4 38.3 167.1 395.7 45.1 72.3 63.7 47.5 105.6 41.3 67.7 191.3 64.4 260.8 87.2 100.9 112.3 46.8 85.4 98.5 70.9 32.4 123.4 127.1 112.5 108.3 111.8 94.7 84.9 60.0 10.0 58.4 48.3 76.3 83.7 95.2 68.4 39.8 105.1 106.7 192.3 57.3 74.9 101.4 71.7 70.6 107.8 44.2 199.0 44.6 69.1 72.3 62.8 116.0 38.0 49.6 104.2 50.8 65.7 110.7 156.0 109.1 88.4 248.2 122.7 63.1 97.7 74.2 99.1 146.7 43.6 138.2 97.9 83.7 105.3 69.2 109.1 59.2 126.5 59.0 85.2 109.0 101.3 47.1 94.3 135.0 91.9 132.7 88.9 51.4 53.7 104.4 115.2 157.4 105.6 99.0 76.6 137.2 67.0 10.0 58.4 8.3 38.6 45.8 68.7 84.9 67.7 50.8 60.0 70.7 76.3 59.4 6.1 48.3 43.8 50.5 58.4 83.7 64.0 57.1 55.7 96.2 51.6 44.4 51.4 38.3 47.5 32.4 EFL1 "EFTUD1, FAM42A, FLJ13119, HsT19294, RIA1" ENSG00000140598 "Elongation factor like GTPase 1" Q7Z2Z2 15 82130230-82262763 "Predicted intracellular proteins" "Protein biosynthesis, Ribosome biogenesis" "Elongation factor" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039654, HPA047110, HPA052345" Uncertain Approved Cytosol Cytosol "HPA039654: , HPA047110: , HPA052345: " "unprognostic (2.53e-1)" "unprognostic (2.04e-1)" "unprognostic (9.92e-3)" "unprognostic (8.99e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-1)" "unprognostic (2.64e-3)" "unprognostic (3.35e-1)" "unprognostic (1.14e-1)" "unprognostic (4.75e-3)" "unprognostic (3.56e-2)" "unprognostic (3.14e-1)" "prognostic favourable (1.50e-6)" "unprognostic (8.58e-2)" "unprognostic (2.96e-1)" "unprognostic (2.60e-1)" "unprognostic (7.05e-2)" 16.3 14.0 7.0 17.3 9.9 8.9 11.8 10.2 9.4 9.5 17.2 11.0 6.8 13.2 9.2 12.2 14.1 9.1 8.0 10.7 8.8 7.9 11.9 15.4 9.0 10.0 9.5 4.5 9.8 12.5 17.9 15.0 12.8 13.3 12.7 19.6 7.4 12.1 8.5 18.5 14.6 25.7 10.8 10.1 10.1 9.7 13.9 9.9 26.9 9.8 11.3 14.9 10.8 11.7 10.7 6.8 15.8 9.0 5.8 9.0 4.5 4.8 12.1 9.1 7.8 6.1 8.4 5.8 14.1 16.7 10.3 13.8 6.0 8.6 11.9 5.8 10.5 12.6 24.0 9.4 16.3 10.5 11.7 13.0 11.6 4.5 9.7 8.4 9.3 4.1 14.6 10.3 23.8 13.5 9.7 5.4 11.8 6.8 10.9 7.6 8.2 6.3 11.7 13.5 6.4 7.2 14.6 8.2 8.8 8.9 10.5 10.8 7.8 7.5 11.3 14.5 9.8 36.3 14.0 6.9 25.9 10.1 13.2 15.8 5.4 15.8 5.6 13.7 9.0 8.1 7.2 8.9 8.4 7.6 6.8 10.7 7.3 6.3 1.0 5.8 9.0 3.3 7.6 4.5 7.0 9.9 10.2 9.4 8.8 7.9 9.5 4.5 13.3 9.9 ENTPD1 "ATPDase, CD39, NTPDase-1, SPG64" ENSG00000138185 "Ectonucleoside triphosphate diphosphohydrolase 1" P49961 10 95711779-95869695 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Hydrolase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 59.4" "Group enriched" "Detected in some" 7 "HDLM-2: 56.0;Karpas-707: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 37.4" "Low lineage specificity" "Detected in many" "CAB002494, HPA014067" Enhanced Uncertain Microtubules Microtubules "CAB002494: AB_563557, HPA014067: AB_1848178" "unprognostic (1.14e-1)" "unprognostic (1.01e-2)" "unprognostic (3.11e-1)" "unprognostic (5.67e-2)" "unprognostic (9.68e-3)" "unprognostic (3.45e-3)" "unprognostic (6.31e-2)" "unprognostic (5.26e-3)" "unprognostic (2.73e-1)" "unprognostic (1.28e-2)" "unprognostic (6.40e-2)" "unprognostic (1.41e-1)" "prognostic unfavourable (5.33e-5)" "unprognostic (9.79e-2)" "unprognostic (2.30e-1)" "prognostic favourable (7.89e-4)" "unprognostic (5.09e-2)" 10.4 7.5 7.4 16.2 8.4 15.6 8.8 7.6 6.9 18.9 12.7 13.1 8.7 5.8 59.4 12.8 13.2 15.6 22.2 6.8 7.4 7.4 6.2 3.9 14.8 14.5 8.5 4.9 10.3 2.8 3.0 4.3 24.0 9.9 14.7 9.1 10.8 6.7 12.7 3.3 5.5 12.2 37.2 17.9 25.3 7.5 5.4 7.2 3.5 13.4 12.5 21.1 25.2 12.4 6.0 11.8 37.4 15.2 0.5 5.1 4.6 0.1 0.3 0.9 0.8 0.0 0.0 0.5 0.5 0.4 0.0 0.0 0.5 0.1 1.0 0.6 0.0 0.2 0.0 0.0 0.0 56.0 0.7 0.6 0.4 0.7 0.0 1.5 0.2 0.0 0.0 0.2 0.0 7.4 0.6 46.0 0.0 0.6 0.4 1.5 0.6 0.2 2.3 0.3 0.7 0.5 0.2 0.7 1.0 0.3 1.1 0.7 0.5 1.6 0.8 0.4 0.2 0.6 0.6 6.6 0.9 0.0 0.6 3.1 0.2 0.1 15.2 37.4 0.1 10.7 0.3 6.0 0.6 0.3 11.8 4.6 0.1 0.1 26.7 0.5 2.4 0.7 5.1 4.6 7.4 8.4 7.6 6.9 7.4 7.4 8.5 4.9 9.9 7.2 ENTPD2 "CD39L1, NTPDase-2" ENSG00000054179 "Ectonucleoside triphosphate diphosphohydrolase 2" Q9Y5L3 9 137048098-137054045 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell line enhanced" "Detected in some" "Hep G2: 16.6;hTCEpi: 9.2;MCF7: 11.5;SK-BR-3: 15.5;T-47d: 16.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13 "eosinophil: 2.6" "Lineage enriched" "Detected in single" 13 "granulocytes: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017676 Approved "HPA017676: AB_1848179" "unprognostic (1.64e-1)" "unprognostic (3.35e-2)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (2.15e-3)" "unprognostic (1.07e-1)" "prognostic unfavourable (2.48e-5)" "unprognostic (2.71e-2)" "unprognostic (4.97e-2)" "unprognostic (3.23e-1)" "unprognostic (2.99e-1)" "unprognostic (1.89e-1)" "prognostic favourable (3.51e-6)" "prognostic favourable (1.38e-4)" "unprognostic (2.51e-1)" "unprognostic (8.43e-2)" "unprognostic (1.12e-3)" 1.7 1.6 18.8 1.5 10.1 0.6 7.0 4.0 10.4 9.8 9.1 21.9 1.7 17.6 2.8 4.4 3.3 9.4 10.7 2.7 22.6 9.6 4.5 1.0 1.0 0.5 6.1 12.8 0.8 2.6 1.2 3.1 3.9 11.9 11.2 5.8 2.5 6.2 2.9 3.0 9.3 11.1 1.9 7.5 0.5 9.5 6.8 11.7 0.0 0.7 2.6 1.0 0.9 3.5 0.0 0.0 2.6 0.1 0.0 0.0 0.0 4.4 1.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.8 1.3 0.0 1.0 0.0 3.6 0.3 2.6 0.0 0.0 0.1 0.0 0.5 16.6 0.0 0.0 0.2 0.0 9.2 0.0 2.4 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 2.5 0.0 0.8 1.7 2.0 0.4 2.5 0.1 0.2 15.5 0.0 16.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.8 10.1 4.0 9.8 22.6 9.6 6.1 12.8 11.9 11.7 ENTPD3 "CD39L3, HB6, NTPDase-3" ENSG00000168032 "Ectonucleoside triphosphate diphosphohydrolase 3" O75355 3 40387156-40428619 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 26.2;pancreas: 37.3" "Cell line enhanced" "Detected in some" "HBEC3-KT: 12.4;hTCEpi: 8.4;RT4: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "plasmacytoid DC: 7.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (1.00e-1)" "unprognostic (1.54e-2)" "unprognostic (2.75e-2)" "unprognostic (9.84e-3)" "unprognostic (2.27e-2)" "unprognostic (2.04e-1)" "unprognostic (1.80e-1)" "unprognostic (1.18e-2)" "unprognostic (8.40e-2)" "unprognostic (9.88e-3)" "unprognostic (4.72e-2)" "unprognostic (2.08e-1)" "unprognostic (3.25e-1)" "unprognostic (6.53e-2)" "unprognostic (5.99e-2)" "unprognostic (1.68e-1)" "unprognostic (1.23e-1)" 4.6 2.2 5.7 1.7 25.9 0.5 2.1 5.4 15.8 26.2 3.3 0.6 1.9 1.7 4.0 4.4 7.5 1.3 3.6 1.4 4.9 6.3 3.6 0.5 4.8 0.9 4.0 6.3 2.6 37.3 1.7 4.2 2.9 14.5 5.3 3.6 2.8 21.2 5.1 1.7 3.2 1.6 2.5 1.7 5.1 8.8 1.3 4.8 0.0 7.0 5.6 4.8 13.7 2.9 0.5 7.4 1.4 0.3 0.9 0.8 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 3.7 0.0 12.4 0.3 0.7 0.4 0.7 0.5 0.2 0.0 0.0 0.0 0.1 8.4 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.1 0.1 1.1 0.1 0.0 0.3 1.5 17.9 1.9 0.4 0.8 1.4 0.3 0.6 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.3 0.0 1.0 0.1 0.1 1.4 0.2 0.0 0.2 0.3 0.8 0.3 0.2 0.3 0.0 0.5 0.6 0.6 0.0 0.9 0.2 7.4 0.6 0.1 5.7 25.9 5.4 15.8 4.9 6.3 4.0 6.3 14.5 4.8 ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA017655 Supported Supported Vesicles 28000 Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" 16.3 11.5 15.0 21.9 19.8 25.7 15.3 20.3 27.4 15.2 18.5 14.7 15.7 17.0 18.8 17.9 13.3 12.7 14.4 21.0 14.5 12.8 13.0 14.4 19.9 26.0 16.2 12.2 14.7 26.5 30.4 25.2 19.3 20.6 17.6 20.2 18.0 19.5 13.7 14.9 12.2 26.1 16.1 14.5 26.9 19.1 18.7 15.8 17.0 15.8 9.3 30.7 16.7 16.7 9.7 8.0 15.9 9.5 4.4 10.7 6.8 9.9 13.7 17.2 11.9 15.1 19.2 17.6 15.9 15.2 10.8 16.9 19.6 13.2 16.8 11.5 16.0 12.1 7.8 14.4 20.8 4.0 5.4 8.9 8.5 6.8 12.3 4.7 17.7 11.7 17.5 14.4 15.4 15.4 6.1 15.5 18.2 4.5 6.8 5.7 10.0 5.0 6.8 17.2 5.1 13.8 11.8 13.7 13.1 6.0 8.7 11.7 6.4 6.7 19.1 19.7 19.4 22.0 11.7 12.4 5.2 22.0 26.3 5.6 19.7 14.9 6.0 13.7 8.5 9.5 10.0 9.7 8.3 9.1 8.0 6.7 10.7 8.3 15.9 4.4 6.9 7.3 6.5 6.8 15.0 19.8 20.3 27.4 14.5 12.8 16.2 12.2 20.6 15.8 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5" O75356 14 73958010-74019399 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 52.0;kidney: 43.1;liver: 71.4" "Cell line enhanced" "Detected in all" "RT4: 33.8" "Cancer enhanced" "Detected in all" "prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 15.0;eosinophil: 8.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced Approved Cytosol "Secreted to blood" 5000000 Cytosol "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favourable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 3.0 3.6 2.8 9.4 3.8 1.7 3.5 3.0 4.0 2.4 25.8 5.8 3.1 19.3 3.0 2.7 4.5 2.4 6.6 2.6 2.8 2.3 43.1 71.4 2.3 1.3 3.5 2.3 3.3 5.9 1.8 2.7 2.2 5.5 10.2 29.6 3.2 4.7 1.5 3.8 2.7 52.0 3.9 5.5 3.2 11.8 4.5 2.5 2.1 2.7 3.0 3.3 9.5 3.0 1.6 1.6 15.0 2.1 0.6 2.5 1.2 5.3 4.3 4.9 9.1 9.8 9.3 5.7 5.6 4.6 3.7 4.3 3.3 6.4 6.0 2.8 7.6 6.3 4.9 8.1 4.2 5.1 2.3 4.5 3.2 17.8 9.5 2.7 5.3 7.6 8.2 5.3 11.0 7.5 5.0 9.3 5.5 7.6 3.0 3.3 1.5 9.4 3.5 4.7 2.9 6.6 33.8 3.5 3.7 9.5 7.5 5.4 10.9 2.4 6.2 7.6 7.9 4.5 4.1 6.0 9.4 4.9 4.8 5.0 6.8 15.0 1.2 8.3 2.5 2.1 1.3 1.3 1.3 1.7 1.6 1.6 2.1 2.1 0.2 0.6 1.3 0.8 1.4 1.2 2.8 3.8 3.0 4.0 2.8 2.3 3.5 2.3 5.5 2.5 ENTPD6 "CD39L2, dJ738P15.3, IL6ST2, NTPDase-6" ENSG00000197586 "Ectonucleoside triphosphate diphosphohydrolase 6 (putative)" O75354 20 25195693-25226729 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015491, HPA069555" Approved Supported "Golgi apparatus" "Secreted to blood" 18000 "Golgi apparatus" "HPA015491: , HPA069555: " "unprognostic (3.24e-1)" "unprognostic (1.27e-2)" "unprognostic (5.91e-2)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (4.44e-1)" "unprognostic (2.10e-3)" "unprognostic (7.41e-3)" "unprognostic (2.74e-3)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (8.14e-3)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (4.86e-2)" "unprognostic (4.48e-2)" 12.7 19.7 21.8 11.3 46.5 6.7 12.8 33.1 49.1 9.8 31.3 12.1 12.8 31.6 9.4 10.1 9.0 12.5 18.3 27.5 24.9 25.0 13.4 12.9 11.0 7.4 15.1 29.2 16.1 25.6 11.7 20.5 13.2 15.4 25.5 24.5 9.0 36.8 9.7 15.1 6.8 32.2 9.9 8.2 8.3 24.7 16.1 10.5 9.4 10.4 6.1 8.3 10.2 7.1 7.2 17.1 3.0 16.0 8.8 17.9 12.9 20.4 32.4 8.9 17.0 11.2 14.1 19.1 16.8 12.2 14.6 13.5 17.3 15.8 12.4 25.4 16.2 26.8 10.8 25.6 9.7 7.6 9.7 10.1 4.9 39.1 16.8 13.4 15.5 13.2 14.3 18.4 14.0 11.7 13.1 21.7 10.8 19.6 12.5 8.3 5.6 25.4 7.1 27.8 28.4 18.3 12.8 14.2 7.4 4.6 28.5 75.7 20.8 11.3 12.7 17.1 17.8 14.0 19.8 13.6 11.0 5.4 12.2 8.9 32.0 0.0 16.0 3.0 12.7 10.7 17.9 6.1 11.4 10.4 17.1 7.2 12.2 10.6 0.7 8.8 4.8 12.0 10.6 12.9 21.8 46.5 33.1 49.1 24.9 25.0 15.1 29.2 15.4 10.5 ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 48.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.0;RPMI-8226: 8.7;T-47d: 4.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Cytosol" Vesicles "HPA021509: AB_1848185" "unprognostic (3.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.70e-2)" "unprognostic (3.87e-2)" "unprognostic (8.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-2)" "unprognostic (1.08e-5)" "prognostic favourable (7.17e-4)" "unprognostic (2.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" 0.4 0.0 0.4 2.6 0.4 0.0 0.4 0.4 0.4 0.4 19.2 0.4 0.4 18.5 0.4 0.4 0.4 0.3 2.2 0.4 0.5 0.0 2.1 9.8 0.8 0.4 0.4 0.4 0.4 1.8 0.0 4.2 0.5 0.4 0.4 7.5 0.8 4.1 0.4 0.4 0.0 48.1 0.4 0.4 0.4 6.1 0.4 0.4 0.6 0.4 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.0 9.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 1.5 0.2 0.0 0.6 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 1.6 0.0 0.2 0.1 0.4 0.0 0.0 8.7 1.4 0.0 0.3 0.9 0.2 0.0 0.1 4.7 0.2 0.1 0.0 2.4 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.5 0.0 0.4 0.4 0.4 0.4 GART "GARS-AIRS-GART, PGFT, PRGS" ENSG00000159131 "Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" P22102 21 33503931-33543491 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Ligase, Multifunctional enzyme, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002119, HPA005779" Approved Uncertain Nucleoplasm,Mitochondria,Cytosol 1300000 "Nucleoplasm, Mitochondria, Cytosol" "HPA002119: AB_1849482, HPA005779: AB_1849484" "unprognostic (3.77e-2)" "unprognostic (2.25e-2)" "unprognostic (4.51e-3)" "unprognostic (1.72e-2)" "unprognostic (2.30e-2)" "prognostic unfavourable (5.05e-5)" "prognostic unfavourable (9.82e-5)" "unprognostic (2.50e-2)" "unprognostic (2.76e-3)" "unprognostic (2.92e-1)" "prognostic unfavourable (2.19e-4)" "unprognostic (1.98e-3)" "prognostic unfavourable (3.95e-6)" "unprognostic (1.36e-2)" "unprognostic (2.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" 24.9 24.7 16.0 20.0 22.3 14.2 22.2 14.5 20.3 16.2 20.1 20.5 13.3 18.9 21.7 15.9 28.1 19.9 14.3 19.3 16.4 14.9 19.2 33.6 18.3 24.4 21.9 14.6 21.0 30.6 21.6 22.9 23.1 21.0 16.4 26.9 19.5 18.6 16.1 33.2 17.6 19.1 23.5 17.9 21.4 21.9 47.0 21.7 40.8 20.0 19.4 32.8 21.6 17.6 18.7 19.5 9.7 20.9 27.1 21.1 13.3 30.0 14.3 21.2 23.5 15.6 16.1 23.8 19.5 16.5 22.8 24.2 27.1 25.6 40.0 11.6 13.0 15.9 44.4 30.6 33.3 21.0 26.4 60.3 17.1 17.7 21.3 33.5 15.9 14.2 21.4 26.9 39.6 21.5 70.1 25.7 20.6 14.4 35.3 22.5 46.2 16.9 29.5 39.5 56.6 18.3 16.1 22.6 20.3 27.0 21.3 25.2 27.0 21.5 15.8 15.5 18.6 13.4 20.8 25.6 35.4 43.7 16.3 39.5 22.9 5.3 15.2 9.7 17.3 20.9 21.1 18.7 16.9 17.9 19.5 14.4 17.7 17.4 7.0 27.1 17.7 14.7 20.6 13.3 16.0 22.3 14.5 20.3 16.4 14.9 21.9 14.6 21.0 21.7 GFM1 "EFGM, EGF1, GFM" ENSG00000168827 "G elongation factor mitochondrial 1" Q96RP9 3 158644278-158692575 "Disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034764, HPA034765, HPA061405" Enhanced Approved Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA034764: AB_2674320, HPA034765: AB_10669849, HPA061405: AB_2684505" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (5.48e-3)" "unprognostic (4.48e-3)" "unprognostic (1.84e-1)" "unprognostic (3.40e-1)" "unprognostic (4.75e-2)" "unprognostic (6.05e-2)" "unprognostic (2.48e-1)" "unprognostic (8.36e-2)" "prognostic unfavourable (9.20e-4)" "unprognostic (2.79e-1)" "prognostic favourable (1.16e-7)" "unprognostic (1.62e-1)" "unprognostic (4.78e-1)" "unprognostic (3.32e-2)" "unprognostic (8.78e-2)" 20.1 23.3 17.6 14.1 18.6 14.7 19.8 32.8 23.4 11.4 20.7 17.8 19.1 18.8 15.4 17.9 16.2 14.3 12.6 27.9 18.0 17.9 34.1 42.2 13.5 13.2 18.9 19.5 13.2 17.0 30.9 16.4 17.4 22.6 15.3 23.3 13.8 16.3 15.4 46.5 15.4 16.0 16.0 18.5 14.2 17.1 19.8 17.8 14.5 21.4 17.6 13.6 15.0 13.2 13.2 16.5 10.8 19.8 16.0 21.1 11.5 30.4 17.5 8.5 10.2 13.6 8.9 11.4 15.7 13.8 22.0 17.2 23.3 18.8 26.1 19.9 11.7 18.5 19.0 14.6 24.6 14.5 12.8 21.7 11.9 12.9 15.5 27.8 11.8 12.3 17.3 14.2 13.2 14.7 22.5 16.0 20.0 16.8 16.3 11.1 19.2 11.8 15.9 10.2 42.0 17.5 12.8 15.4 14.9 24.8 33.6 26.7 41.4 22.7 10.8 14.7 7.3 23.0 24.8 30.9 19.4 47.5 13.9 23.4 16.4 10.8 13.2 9.1 16.1 19.8 21.1 13.2 15.0 16.9 16.5 11.9 17.6 18.5 1.9 16.0 14.0 8.6 11.9 11.5 17.6 18.6 32.8 23.4 18.0 17.9 18.9 19.5 22.6 17.8 GFM2 "EFG2, FLJ21661" ENSG00000164347 "G elongation factor mitochondrial 2" Q969S9 5 74721204-74767371 "Predicted intracellular proteins" "Protein biosynthesis" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036863, HPA069871" Uncertain Approved Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA036863: , HPA069871: " "unprognostic (2.58e-3)" "unprognostic (7.04e-2)" "unprognostic (8.54e-3)" "unprognostic (1.98e-1)" "unprognostic (4.49e-2)" "unprognostic (2.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.64e-1)" "unprognostic (1.40e-1)" "unprognostic (3.80e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "prognostic favourable (1.33e-5)" "unprognostic (9.55e-2)" "unprognostic (4.15e-1)" "unprognostic (8.52e-3)" "unprognostic (9.82e-2)" 9.7 23.8 14.7 8.7 22.4 12.1 13.1 14.2 24.8 10.7 12.8 12.7 17.8 8.3 12.3 16.8 13.0 21.6 8.7 29.5 18.5 15.6 21.9 30.8 9.1 10.3 13.8 18.1 11.6 12.9 19.8 24.9 12.9 20.4 12.5 15.3 11.6 15.7 11.2 26.4 10.5 10.3 10.4 11.7 10.3 16.3 13.7 10.4 18.0 12.3 12.8 14.2 12.3 12.6 8.3 6.1 17.1 9.8 15.6 7.4 4.6 19.9 17.1 14.4 27.3 11.0 14.9 14.7 22.0 13.4 22.5 24.1 18.7 13.0 20.7 23.5 11.6 16.7 29.0 30.7 29.3 18.2 17.0 12.2 17.3 12.8 14.0 11.9 13.5 16.7 13.7 17.8 21.4 15.2 20.5 17.2 25.5 11.2 16.4 7.3 5.9 15.5 20.6 23.6 23.5 16.4 12.8 24.3 13.1 25.4 19.6 21.7 17.0 20.7 12.1 8.6 14.8 10.9 13.9 10.0 19.3 20.9 13.2 17.0 13.1 17.1 6.3 8.0 6.6 6.5 6.4 8.3 5.4 7.2 6.1 7.0 7.4 7.2 3.3 15.6 9.8 4.0 6.2 4.6 14.7 22.4 14.2 24.8 18.5 15.6 13.8 18.1 20.4 10.4 IL18BP IL18BPa ENSG00000137496 "Interleukin 18 binding protein" O95998 11 71998541-72005715 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 54.3;lymphoid tissue: 71.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB025980, HPA041061" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" 3072700 14000000 "Endoplasmic reticulum" "CAB025980: , HPA041061: " "unprognostic (2.66e-3)" "unprognostic (2.04e-3)" "unprognostic (9.14e-3)" "unprognostic (1.70e-2)" "unprognostic (5.58e-3)" "unprognostic (7.75e-2)" "unprognostic (1.41e-1)" "unprognostic (6.20e-2)" "unprognostic (1.19e-2)" "unprognostic (1.75e-3)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "prognostic unfavourable (2.93e-6)" "unprognostic (1.19e-1)" "unprognostic (4.14e-2)" "unprognostic (6.76e-2)" "unprognostic (1.93e-2)" 23.7 10.6 6.5 19.7 7.7 6.0 7.2 6.2 5.7 6.3 6.7 6.7 1.0 7.1 6.1 4.1 4.1 5.8 7.2 4.7 3.8 4.1 37.0 54.3 20.8 20.2 7.0 1.9 10.1 4.9 2.8 6.4 28.4 9.0 8.9 9.8 5.3 6.4 4.0 6.2 5.1 9.2 11.4 6.1 71.5 6.1 3.0 6.3 6.1 17.3 3.6 15.6 8.6 6.2 13.6 22.3 22.2 30.5 1.9 23.4 13.9 2.0 2.6 6.2 3.5 1.3 1.9 7.0 3.3 1.9 3.2 4.5 13.0 2.5 1.2 2.6 1.6 5.0 3.7 2.7 2.6 2.9 4.3 5.2 7.0 3.7 1.4 3.0 12.4 2.9 3.1 3.0 1.6 6.3 8.8 2.2 1.8 3.4 3.8 6.4 4.4 2.5 5.8 6.4 2.1 2.2 5.5 3.3 6.4 3.7 4.2 4.9 4.2 2.7 13.7 5.3 4.1 6.1 2.1 3.6 2.1 2.5 2.3 10.9 2.6 2.3 8.5 22.2 23.4 30.5 10.5 13.6 12.4 13.8 15.5 7.0 10.4 15.0 3.6 1.9 23.7 22.3 6.1 13.9 6.5 7.7 6.2 5.7 3.8 4.1 7.0 1.9 9.0 6.3 ITPA "C20orf37, dJ794I6.3, HLC14-06-P" ENSG00000125877 "Inosine triphosphatase" Q9BY32 20 3208868-3223870 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022824, HPA073963" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" 69000 Cytosol "Nucleoplasm, Nuclear bodies" "HPA022824: AB_1851960, HPA073963: " "unprognostic (1.58e-2)" "unprognostic (1.98e-1)" "unprognostic (1.73e-1)" "unprognostic (3.57e-1)" "unprognostic (4.63e-2)" "unprognostic (1.53e-2)" "prognostic unfavourable (2.54e-5)" "unprognostic (1.11e-2)" "unprognostic (1.68e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-1)" "unprognostic (1.94e-2)" "unprognostic (8.34e-2)" "unprognostic (3.63e-1)" "unprognostic (1.24e-1)" "unprognostic (1.84e-1)" 17.7 27.5 18.6 24.7 21.2 20.4 17.7 10.2 22.7 21.3 21.4 18.3 20.6 22.9 18.1 17.3 31.0 26.6 19.6 25.9 18.1 13.5 22.9 20.3 22.7 30.6 20.5 24.1 16.5 43.8 17.6 10.2 17.0 16.2 14.6 16.8 13.2 19.9 21.5 19.5 23.4 19.0 16.3 16.3 20.6 19.3 16.7 19.5 15.2 24.9 29.0 24.1 14.6 17.7 19.3 30.7 11.3 31.0 24.7 24.1 18.2 33.1 26.2 13.0 13.4 8.6 12.7 8.6 15.0 21.0 19.8 17.4 21.0 30.9 14.3 13.8 13.8 28.9 17.8 22.6 13.9 9.3 26.6 35.8 10.9 31.8 16.3 15.3 12.2 12.1 17.3 18.7 11.6 15.1 24.5 9.9 17.8 15.2 18.0 44.4 21.7 26.5 17.3 18.1 37.5 27.1 10.5 19.7 23.2 11.9 41.7 27.6 17.3 25.6 10.6 22.3 12.4 14.6 31.8 14.7 18.4 27.0 10.4 28.4 24.2 11.3 25.7 8.8 20.7 31.0 18.0 19.3 18.9 21.8 30.7 17.8 14.2 17.2 1.4 24.7 21.9 28.3 24.1 18.2 18.6 21.2 10.2 22.7 18.1 13.5 20.5 24.1 16.2 19.5 MTPAP "FLJ10486, mtPAP, PAPD1, SPAX4" ENSG00000107951 "Mitochondrial poly(A) polymerase" Q9NVV4 10 30309801-30374448 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transcription" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038620, HPA058232" Approved Supported Mitochondria Mitochondria "HPA038620: AB_10673015, HPA058232: " "unprognostic (2.76e-2)" "unprognostic (2.04e-1)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (3.05e-2)" "unprognostic (1.01e-1)" "prognostic unfavourable (4.20e-6)" "unprognostic (1.16e-1)" "unprognostic (2.04e-1)" "unprognostic (4.78e-2)" "unprognostic (1.77e-1)" "unprognostic (3.56e-2)" "unprognostic (9.02e-2)" "unprognostic (6.28e-3)" "unprognostic (3.77e-1)" "unprognostic (1.14e-2)" "unprognostic (4.39e-2)" 10.9 12.7 9.9 10.2 12.4 32.8 11.1 12.4 16.1 9.6 9.9 7.3 6.5 11.0 10.4 7.0 12.6 9.5 7.6 11.5 7.8 7.2 10.6 11.1 9.4 10.5 11.9 13.0 11.4 18.9 9.5 7.2 10.0 11.4 8.0 12.0 8.2 10.7 10.2 22.3 13.1 10.0 14.3 9.0 9.3 9.7 10.6 8.3 6.7 11.0 12.4 10.5 11.7 9.1 15.6 22.9 18.4 24.4 16.9 17.1 8.3 14.2 14.2 9.0 13.1 8.9 8.4 11.7 9.9 3.5 10.1 10.6 15.0 20.0 20.3 7.1 6.5 16.8 17.4 11.5 12.4 10.2 13.6 20.6 13.4 15.1 9.3 13.4 16.2 8.2 10.8 11.3 6.8 11.0 22.2 16.0 7.6 11.9 16.1 11.9 6.1 7.7 16.3 16.0 18.9 9.3 9.5 14.9 12.0 9.0 9.4 13.8 9.0 8.7 10.5 10.7 13.8 14.9 11.0 3.6 8.6 27.8 9.2 24.7 3.7 16.4 18.5 18.4 16.2 24.4 17.1 15.6 15.4 15.6 22.9 13.1 16.7 16.8 3.0 16.9 18.1 12.0 15.5 8.3 9.9 12.4 12.4 16.1 7.8 7.2 11.9 13.0 11.4 8.3 MYBBP1A "FLJ37886, P160, PAP2, Pol5" ENSG00000132382 "MYB binding protein 1a" Q9BQG0 17 4538897-4555631 "Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Ribosome biogenesis, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005466 Supported Supported Nucleoli,Vesicles Nucleoli Vesicles "HPA005466: AB_2667327" "unprognostic (8.06e-2)" "unprognostic (2.33e-1)" "unprognostic (1.71e-1)" "unprognostic (9.01e-2)" "unprognostic (7.81e-2)" "unprognostic (1.29e-1)" "unprognostic (1.57e-3)" "unprognostic (2.22e-1)" "prognostic unfavourable (8.47e-4)" "unprognostic (1.84e-1)" "prognostic favourable (1.61e-4)" "unprognostic (3.88e-3)" "prognostic unfavourable (5.95e-4)" "unprognostic (1.78e-1)" "unprognostic (1.32e-1)" "prognostic unfavourable (8.12e-4)" "unprognostic (9.70e-2)" 14.1 11.6 13.8 16.5 14.6 13.2 16.2 15.0 21.5 11.3 10.2 14.9 11.1 12.9 15.4 11.7 17.1 15.8 12.4 11.5 11.7 9.2 8.7 21.5 11.6 16.0 15.2 11.1 15.3 23.7 10.5 13.1 7.2 13.0 17.0 7.2 12.7 24.5 15.3 30.8 25.0 12.8 10.9 7.3 15.0 12.9 9.3 12.6 14.6 11.7 18.2 17.6 15.4 13.2 5.3 4.9 0.4 4.9 4.3 5.9 3.8 19.4 31.2 4.1 18.8 5.3 6.2 14.0 13.5 6.0 13.7 10.6 23.0 8.0 26.6 15.8 8.0 24.7 17.0 20.4 6.4 13.3 45.8 12.8 19.3 20.3 8.5 15.0 11.7 9.0 11.7 20.1 10.0 9.1 20.9 12.3 5.8 16.9 17.5 5.9 18.8 16.3 22.7 6.9 17.6 3.2 15.7 8.7 16.7 13.8 9.7 9.1 9.3 6.1 11.7 11.9 10.7 11.1 38.7 11.1 7.5 10.8 11.3 17.6 15.2 0.0 2.8 0.4 5.1 2.7 5.9 5.3 4.2 5.5 4.9 3.3 4.5 4.6 0.1 4.3 4.9 3.5 1.8 3.8 13.8 14.6 15.0 21.5 11.7 9.2 15.2 11.1 13.0 12.6 NME1 "NDPKA, NM23, NM23-H1" ENSG00000239672 "NME/NM23 nucleoside diphosphate kinase 1" P15531 17 51153536-51162428 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008467, CAB040571, HPA041113" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" 28000000 Cytosol "Nucleoplasm, Plasma membrane" "CAB040571: , HPA008467: AB_1079492, HPA041113: " "unprognostic (2.24e-1)" "unprognostic (2.01e-1)" "unprognostic (3.48e-3)" "unprognostic (5.96e-2)" "unprognostic (9.71e-2)" "unprognostic (2.33e-3)" "prognostic unfavourable (2.60e-5)" "unprognostic (4.54e-2)" "unprognostic (3.35e-1)" "unprognostic (2.33e-3)" "unprognostic (2.90e-2)" "unprognostic (1.01e-1)" "prognostic unfavourable (2.07e-9)" "unprognostic (9.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.83e-1)" "unprognostic (9.46e-2)" 25.0 29.5 38.0 28.1 30.1 27.9 29.0 19.6 41.9 16.4 25.4 13.1 10.1 15.1 17.3 22.5 30.1 22.2 13.4 14.1 41.7 39.4 19.6 56.0 14.2 28.5 34.2 34.2 15.6 43.6 13.7 17.3 16.9 38.9 14.5 36.8 14.9 34.3 14.7 14.8 22.4 12.4 29.6 20.5 22.4 13.4 11.6 11.3 19.0 18.8 32.7 41.4 22.8 15.2 24.9 36.2 0.6 19.5 17.2 20.3 18.4 47.6 95.2 32.9 45.9 13.8 22.1 55.3 37.2 25.8 77.1 58.5 74.9 28.9 83.9 38.8 34.4 25.6 62.8 63.2 66.0 40.7 84.6 55.0 73.9 103.9 28.0 60.2 25.2 21.0 39.8 58.0 54.3 46.4 81.1 27.9 45.6 80.7 71.5 69.3 39.4 86.8 43.9 64.9 77.2 59.2 33.3 45.7 52.6 19.5 53.4 34.6 55.6 40.8 29.2 49.8 45.2 30.9 76.3 36.0 83.0 98.8 30.1 51.1 37.8 0.2 15.2 0.6 13.4 19.5 20.3 24.9 14.4 14.6 36.2 17.3 16.4 17.8 0.4 17.2 11.5 20.7 12.1 18.4 38.0 30.1 19.6 41.9 41.7 39.4 34.2 34.2 38.9 11.3 NME1-NME2 "NM23-LV, NMELV" ENSG00000011052 "NME1-NME2 readthrough" 17 51153590-51171744 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB002169, HPA008467, HPA041113, CAB076057" Approved Approved Cytosol Cytosol "CAB002169: AB_563917, CAB076057: , HPA008467: AB_1079492, HPA041113: " "unprognostic (2.39e-1)" "unprognostic (5.29e-2)" "unprognostic (9.70e-2)" "unprognostic (5.13e-2)" "prognostic favourable (6.66e-4)" "unprognostic (2.46e-2)" "unprognostic (4.82e-3)" "unprognostic (8.39e-2)" "unprognostic (2.30e-2)" "unprognostic (1.53e-1)" "unprognostic (4.58e-6)" "unprognostic (1.03e-1)" "unprognostic (2.74e-6)" "unprognostic (1.84e-1)" "unprognostic (9.72e-2)" "unprognostic (1.50e-1)" "unprognostic (1.43e-3)" 12.8 29.3 19.7 35.5 16.7 20.6 8.5 13.9 31.2 5.4 7.2 6.7 4.9 14.7 10.6 6.2 10.6 7.4 6.8 8.0 23.0 17.0 10.4 31.3 7.8 18.3 16.9 18.7 8.1 24.1 6.5 11.4 13.6 21.5 6.7 5.7 7.7 23.5 4.7 10.1 8.2 10.7 11.7 11.0 11.9 14.8 5.8 5.6 10.0 8.6 17.9 12.7 9.5 7.6 19.6 37.6 1.0 21.1 14.6 21.9 16.2 28.4 1.9 9.2 33.9 8.7 4.4 7.3 22.6 7.3 6.0 3.7 3.7 19.3 16.7 23.6 11.6 17.8 9.0 14.5 3.9 25.1 13.5 13.9 3.5 7.1 10.5 23.3 23.1 8.0 10.9 7.5 10.8 9.5 10.9 21.6 3.8 4.7 57.2 16.1 27.7 2.8 33.9 22.7 49.4 7.0 3.7 29.8 17.5 11.9 51.6 25.9 52.8 39.7 19.0 38.0 27.8 36.9 46.1 37.0 40.0 32.5 21.9 16.8 32.7 0.2 15.1 0.3 15.0 21.1 21.9 19.6 14.7 16.1 37.6 18.4 13.7 16.8 1.0 14.6 11.6 25.7 13.7 16.2 19.7 16.7 13.9 26.4 23.0 17.0 16.9 18.7 21.5 5.6 NME2 "NDPKB, NM23-H2" ENSG00000243678 "NME/NM23 nucleoside diphosphate kinase 2" P22392 17 51165435-51171747 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Nucleotide metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB036213, CAB036214, CAB036215, HPA041113" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB036213: , CAB036214: , CAB036215: , HPA041113: " "unprognostic (7.21e-3)" "prognostic unfavourable (4.74e-4)" "unprognostic (4.85e-2)" "unprognostic (1.15e-2)" "unprognostic (8.86e-2)" "unprognostic (1.42e-2)" "prognostic unfavourable (7.09e-4)" "unprognostic (6.62e-3)" "unprognostic (5.68e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (6.41e-2)" "prognostic unfavourable (1.55e-6)" "unprognostic (2.82e-1)" "unprognostic (9.09e-2)" "unprognostic (8.87e-2)" "unprognostic (3.19e-2)" 62.1 54.6 42.3 58.2 44.1 44.2 188.9 20.1 43.7 58.9 74.0 16.3 67.7 52.5 65.0 52.0 104.3 56.8 65.3 115.1 38.2 32.1 77.3 115.7 59.0 174.7 45.0 23.7 90.7 234.3 17.5 30.4 37.9 34.0 64.0 62.7 29.9 109.4 65.8 105.3 63.3 45.1 88.3 34.6 69.4 50.2 32.3 24.4 42.5 66.9 102.0 56.6 81.3 140.8 49.3 71.3 8.3 43.7 32.6 34.5 38.2 91.8 135.0 32.3 56.4 72.3 105.5 89.2 63.7 66.3 97.5 74.3 108.9 48.9 77.3 103.2 65.2 58.8 67.8 86.9 80.3 93.1 200.5 65.0 94.2 157.6 79.0 102.5 45.5 95.5 101.5 62.9 110.7 58.0 88.9 52.1 70.2 163.4 51.3 128.2 48.2 207.4 49.2 107.1 123.4 105.6 116.1 73.7 45.7 39.2 98.5 95.6 67.9 78.7 58.8 94.0 68.0 66.8 101.2 91.1 118.3 88.5 50.8 52.2 47.1 8.3 35.1 2.0 24.7 43.7 34.5 49.3 33.0 26.9 61.5 36.2 23.8 25.6 2.1 32.6 38.0 71.3 29.9 38.2 42.3 44.1 20.1 43.7 38.2 32.1 45.0 23.7 34.0 24.4 NME3 "DR-nm23, NDPKC, NM23-H3" ENSG00000103024 "NME/NM23 nucleoside diphosphate kinase 3" Q13232 16 1770286-1771730 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 30.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041113, HPA052733" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" 7900000 Nucleoplasm Cytosol "HPA041113: , HPA052733: " "prognostic favourable (6.81e-5)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-3)" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (4.54e-2)" "unprognostic (1.13e-1)" "unprognostic (6.22e-3)" "unprognostic (4.40e-2)" "unprognostic (4.43e-2)" "unprognostic (7.09e-3)" "unprognostic (1.79e-1)" "unprognostic (3.84e-1)" "unprognostic (3.64e-1)" "unprognostic (6.11e-3)" 20.6 45.6 18.0 12.9 19.8 6.6 20.0 21.9 18.2 16.6 18.0 11.0 31.6 25.7 14.4 19.1 12.9 14.3 21.5 11.8 17.5 16.1 17.7 11.2 17.3 11.3 18.4 15.9 22.1 26.8 15.1 24.1 9.7 14.4 26.9 6.4 13.8 34.3 41.4 15.2 9.2 24.6 14.6 14.1 20.4 17.5 7.2 14.6 5.1 24.1 11.7 8.8 11.5 17.9 19.3 34.1 15.5 25.6 20.1 24.4 20.0 0.7 11.6 0.2 9.5 2.7 1.4 1.1 6.8 2.0 1.2 0.9 0.0 13.8 0.1 18.9 0.9 9.8 0.6 3.8 0.1 13.5 30.8 0.0 5.4 5.5 5.1 2.3 4.3 6.3 3.4 1.2 0.6 2.4 4.6 1.9 1.1 16.8 0.2 4.5 12.3 9.4 6.4 0.1 18.0 2.0 0.5 13.5 10.4 20.4 15.4 1.6 14.7 5.6 8.5 2.5 9.6 8.1 4.6 4.9 1.5 1.0 3.5 0.4 5.8 4.9 25.6 15.5 17.5 22.9 17.1 19.3 24.4 16.4 22.0 16.3 21.4 16.8 5.3 20.1 24.5 34.1 21.8 20.0 18.0 19.8 21.9 18.2 17.5 16.1 18.4 15.9 14.4 14.6 NME4 "NDPKD, nm23-H4, NM23H4" ENSG00000103202 "NME/NM23 nucleoside diphosphate kinase 4" O00746 16 396725-410367 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid transport, Nucleotide metabolism, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045997, HPA072588" Approved Supported Mitochondria Mitochondria "CAB045997: AB_11126630, HPA072588: " "unprognostic (3.27e-1)" "prognostic unfavourable (6.53e-4)" "unprognostic (3.70e-2)" "unprognostic (7.16e-3)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.40e-2)" "unprognostic (4.46e-3)" "unprognostic (1.98e-1)" "unprognostic (3.12e-1)" "unprognostic (3.74e-2)" "unprognostic (7.79e-3)" "prognostic unfavourable (1.61e-7)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (6.04e-2)" "unprognostic (3.08e-1)" 34.5 34.4 21.5 13.9 17.6 46.8 34.6 10.4 13.6 25.6 44.6 12.8 40.7 9.7 21.7 33.7 25.1 20.0 39.9 26.9 16.6 16.5 20.2 61.2 13.5 27.5 16.9 11.3 31.9 19.2 22.0 17.3 19.4 11.7 46.9 10.6 32.2 44.4 44.0 13.7 7.5 15.3 83.9 12.4 17.8 27.1 13.3 10.9 19.6 21.0 14.2 14.5 64.1 27.5 13.1 28.6 18.2 6.3 1.2 13.7 5.2 0.1 49.5 44.0 60.4 17.6 31.0 9.8 23.3 28.0 35.3 30.3 33.0 28.8 0.4 17.6 37.1 0.6 23.8 25.0 10.4 19.9 35.5 24.0 6.7 44.0 33.3 17.4 8.8 39.9 13.2 21.6 2.1 22.6 24.8 4.3 26.2 40.5 15.2 22.0 44.8 11.0 76.9 9.8 12.5 24.4 0.2 12.9 69.6 5.9 0.4 21.6 29.4 41.0 28.1 25.2 36.7 16.8 5.8 0.5 0.3 13.1 11.0 3.2 29.0 4.1 6.3 18.2 7.5 5.6 6.5 12.3 7.7 8.3 8.7 13.1 13.7 7.1 2.2 1.2 4.8 28.6 0.4 5.2 21.5 17.6 10.4 13.6 16.6 16.5 16.9 11.3 11.7 10.9 NME5 "nm23-H5, RSPH23" ENSG00000112981 "NME/NM23 family member 5" P56597 5 138115172-138139443 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 28.1;testis: 36.2" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035648, HPA044555" Approved Approved "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA035648: , HPA044555: AB_10960286" "unprognostic (2.49e-2)" "unprognostic (7.63e-4)" "unprognostic (9.97e-2)" "prognostic favourable (7.24e-5)" "unprognostic (3.27e-2)" "unprognostic (2.27e-1)" "unprognostic (3.04e-3)" "unprognostic (3.06e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (1.83e-2)" "unprognostic (2.14e-1)" "prognostic favourable (1.76e-4)" "unprognostic (9.14e-4)" "unprognostic (1.11e-3)" "unprognostic (3.45e-1)" "unprognostic (3.16e-2)" 1.3 5.2 12.3 0.6 18.4 0.3 3.7 3.5 13.9 7.1 1.2 3.9 4.7 0.5 4.1 18.2 1.0 28.1 6.8 2.9 12.0 10.7 15.4 0.6 3.6 0.6 9.4 9.9 4.5 3.5 12.1 8.9 0.4 13.1 4.2 1.1 4.8 3.1 3.9 0.4 0.4 0.5 2.6 4.2 0.4 2.2 36.2 4.8 0.0 9.6 0.3 0.4 2.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.6 0.0 0.0 0.0 0.6 0.4 0.6 0.2 0.1 1.5 0.0 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 1.8 0.0 0.7 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.5 1.2 0.0 0.0 0.0 25.1 0.0 5.7 2.1 0.0 0.7 3.7 0.4 1.3 0.0 0.6 0.0 0.0 0.8 0.4 0.6 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 18.4 3.5 13.9 12.0 10.7 9.4 9.9 13.1 4.8 NME6 "IPIA-ALPHA, NM23-H6" ENSG00000172113 "NME/NM23 nucleoside diphosphate kinase 6" O75414 3 48290722-48301685 "Enzymes, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017909 Approved Approved Vesicles Vesicles "HPA017909: AB_1854530" "unprognostic (7.31e-3)" "unprognostic (1.87e-1)" "unprognostic (8.19e-3)" "unprognostic (2.09e-2)" "unprognostic (8.52e-2)" "unprognostic (2.20e-1)" "prognostic unfavourable (2.17e-7)" "unprognostic (1.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.00e-3)" "unprognostic (1.32e-1)" "unprognostic (2.98e-1)" "prognostic favourable (3.18e-5)" "unprognostic (1.98e-2)" "unprognostic (1.57e-2)" "unprognostic (1.23e-1)" "unprognostic (9.50e-2)" 11.7 12.2 7.0 14.4 11.0 7.7 13.5 9.2 10.9 12.2 12.0 11.9 14.6 13.5 16.1 13.2 16.1 16.3 8.8 13.7 9.9 6.8 18.0 17.5 11.1 12.9 9.2 10.3 14.5 20.6 12.1 13.3 22.1 8.8 13.2 12.7 13.5 20.8 17.6 20.1 10.3 13.4 13.3 7.1 14.2 13.4 9.0 8.2 12.6 17.5 14.3 15.1 13.9 15.7 26.4 23.5 43.3 22.7 23.0 25.8 14.3 17.8 11.1 15.2 11.0 12.4 16.7 13.6 17.5 13.5 25.8 19.6 18.6 15.7 18.0 9.1 13.6 6.2 13.7 19.3 15.3 21.4 13.2 11.7 14.9 15.1 16.6 14.8 12.6 13.6 21.2 22.8 27.3 13.8 19.6 13.9 9.6 8.5 12.4 6.4 12.8 14.6 7.4 13.3 15.1 12.9 15.4 4.7 8.0 11.9 13.2 15.6 14.7 13.8 12.4 5.1 20.2 12.6 24.9 16.5 22.3 16.2 9.7 19.7 11.3 22.0 20.1 43.3 25.8 20.7 23.6 26.4 24.2 21.9 23.5 24.4 18.7 17.7 22.5 23.0 22.7 21.1 19.4 14.3 7.0 11.0 9.2 10.9 9.9 6.8 9.2 10.3 8.8 8.2 NME7 "CFAP67, FLJ37194, NM23-H7" ENSG00000143156 "NME/NM23 family member 7" Q9Y5B8 1 169132531-169367967 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038014, HPA054289" Uncertain Approved Mitochondria Mitochondria "HPA038014: AB_10673037, HPA054289: " "unprognostic (1.28e-1)" "unprognostic (8.52e-2)" "unprognostic (6.21e-2)" "unprognostic (6.30e-2)" "unprognostic (1.11e-1)" "unprognostic (7.44e-3)" "prognostic unfavourable (3.24e-5)" "unprognostic (1.42e-1)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (2.00e-1)" "unprognostic (6.63e-2)" "unprognostic (2.67e-2)" "unprognostic (1.12e-1)" "unprognostic (7.75e-2)" "unprognostic (2.74e-1)" 7.7 12.1 13.5 8.0 22.8 3.7 12.8 14.6 16.8 15.6 11.5 5.5 13.4 4.6 16.0 15.8 8.6 31.1 11.2 8.4 18.9 11.3 13.9 8.6 8.9 6.0 9.5 11.5 17.0 8.1 18.9 39.9 5.6 15.6 9.6 6.7 9.3 5.9 14.3 5.1 4.9 5.5 17.2 9.5 5.2 8.1 17.2 9.6 11.9 15.9 5.8 7.0 10.0 8.2 8.5 5.2 1.7 7.1 9.1 12.0 4.7 10.5 11.3 12.3 9.6 12.4 12.5 4.4 7.3 11.1 13.3 16.9 6.4 16.0 3.1 13.4 6.5 7.4 6.9 15.8 21.8 11.0 5.7 5.6 10.8 6.5 8.5 10.2 3.6 9.1 9.6 13.4 18.2 19.0 5.3 4.3 13.3 3.4 9.2 7.5 12.1 11.6 7.2 13.3 6.8 21.6 3.1 13.3 19.2 11.1 3.3 8.2 11.4 7.4 11.3 8.3 27.5 7.3 17.7 5.2 8.8 6.5 9.1 3.6 8.2 1.4 3.3 1.7 8.3 5.1 10.1 8.5 10.8 8.8 5.2 7.0 9.3 10.6 1.0 9.1 7.1 4.4 12.0 4.7 13.5 22.8 14.6 16.8 18.9 11.3 9.5 11.5 15.6 9.6 NT5C "cdN, DNT-1, DNT1, PN-I, UMPH2" ENSG00000125458 "5', 3'-nucleotidase, cytosolic" Q8TCD5 17 75130225-75131795 "Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021581, HPA023632" Approved Supported Cytosol 600000 Cytosol "HPA021581: AB_1854663, HPA023632: AB_1854662" "unprognostic (3.83e-2)" "unprognostic (4.45e-2)" "unprognostic (2.39e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (9.21e-2)" "prognostic unfavourable (3.05e-4)" "unprognostic (1.26e-1)" "unprognostic (7.25e-2)" "unprognostic (8.26e-3)" "unprognostic (7.15e-2)" "unprognostic (2.22e-1)" "unprognostic (6.57e-2)" "unprognostic (1.58e-1)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" "prognostic favourable (7.66e-4)" 14.5 16.7 10.7 32.5 10.5 14.4 15.2 16.0 13.8 16.3 27.3 18.5 16.2 25.1 18.0 18.7 21.6 15.9 21.0 16.7 9.6 11.0 21.0 13.5 19.9 30.1 12.3 11.0 19.7 28.0 10.4 9.7 11.6 10.9 17.5 14.2 18.0 17.9 17.7 27.1 16.0 30.1 16.7 13.7 20.5 24.5 11.4 12.0 17.2 22.0 30.4 24.5 20.5 17.1 30.7 16.8 46.7 15.8 22.7 14.3 9.7 21.1 33.2 10.9 11.4 3.3 6.9 15.0 12.6 11.1 12.8 8.2 12.4 25.0 14.8 9.2 8.8 14.9 7.6 15.7 7.3 6.9 23.9 16.2 25.8 20.7 16.6 15.7 7.4 10.0 7.5 9.1 25.6 14.1 15.7 7.2 13.0 21.2 11.4 15.9 11.3 22.0 10.4 14.3 20.5 16.6 11.4 13.0 26.6 12.2 15.0 17.4 21.0 11.6 8.2 11.1 27.5 4.2 16.7 14.4 2.1 16.4 10.3 9.6 17.2 46.7 10.2 15.2 13.8 15.8 9.7 30.7 9.0 11.6 12.7 29.1 7.9 11.9 4.6 22.7 15.5 16.8 14.3 9.7 10.7 10.5 16.0 13.8 9.6 11.0 12.3 11.0 10.9 12.0 NT5C1A "CN-I, CN-IA, CN1, CN1A, MGC119199, MGC119201" ENSG00000116981 "5'-nucleotidase, cytosolic IA" Q9BXI3 1 39659121-39672038 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 51.9;tongue: 13.9" "Cell line enriched" "Detected in some" 13 "SH-SY5Y: 19.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050283, HPA054158" Supported "HPA050283: , HPA054158: " "unprognostic (7.85e-2)" "unprognostic (1.60e-1)" "unprognostic (6.19e-1)" "unprognostic (1.51e-3)" "unprognostic (7.19e-2)" "unprognostic (2.87e-1)" "unprognostic (3.34e-1)" "unprognostic (1.32e-1)" "unprognostic (3.29e-2)" "unprognostic (1.81e-2)" 0.7 2.8 1.2 0.8 3.0 0.5 0.5 5.6 7.6 0.7 0.5 1.0 0.0 0.5 0.6 2.9 3.0 0.7 0.5 9.8 1.7 1.7 0.9 0.5 0.5 0.5 1.8 4.9 0.7 6.0 0.5 0.5 0.5 6.9 0.9 0.5 0.0 0.7 0.7 51.9 0.5 0.6 0.6 5.2 0.5 0.6 0.7 1.0 0.0 0.5 13.9 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 19.9 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.0 5.6 7.6 1.7 1.7 1.8 4.9 6.9 1.0 NT5C1B "AIRP, CN-IB" ENSG00000185013 "5'-nucleotidase, cytosolic IB" Q96P26 2 18562872-18589572 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 52.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA056683 Uncertain "HPA056683: " "unprognostic (4.18e-2)" "unprognostic (1.20e-2)" "unprognostic (7.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "unprognostic (4.97e-2)" "unprognostic (4.96e-2)" "unprognostic (4.84e-1)" "unprognostic (8.49e-2)" "unprognostic (4.42e-2)" "unprognostic (2.91e-2)" "unprognostic (2.35e-1)" "unprognostic (1.61e-1)" "unprognostic (6.96e-2)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (3.77e-1)" 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.3 0.7 0.0 0.4 0.3 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.8 0.1 0.1 0.1 0.1 0.5 52.6 0.1 0.1 0.5 0.1 0.1 0.5 0.1 1.2 3.7 0.0 0.1 0.7 2.6 0.4 3.2 0.7 0.3 0.0 0.0 0.0 0.5 2.5 0.0 0.0 0.0 0.0 3.5 1.6 0.5 0.0 1.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.9 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 1.1 0.2 0.0 2.9 0.1 0.2 0.7 1.7 0.3 0.7 0.8 0.1 3.0 2.5 1.2 2.6 0.4 1.5 0.8 0.7 1.7 1.5 1.0 2.9 0.5 1.0 0.7 2.0 2.5 0.0 1.2 0.0 0.1 0.0 1.3 0.0 2.3 0.1 1.3 1.3 0.3 1.2 2.6 2.2 0.0 0.7 0.1 3.7 0.5 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 NT5C1B-RDH14 ENSG00000250741 "NT5C1B-RDH14 readthrough" 2 18555545-18589564 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 74 "testis: 49.4" "Cell line enhanced" "Detected in single" "TIME: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056683 Uncertain "HPA056683: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NT5C2 "cN-II, GMP, NT5B, PNT5, SPG65" ENSG00000076685 "5'-nucleotidase, cytosolic II" P49902 10 103088017-103193306 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Allosteric enzyme, Hydrolase" "Cancer-related genes, Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003751 Approved "HPA003751: AB_1854664" "unprognostic (8.18e-2)" "unprognostic (1.98e-1)" "unprognostic (2.55e-2)" "unprognostic (2.46e-1)" "unprognostic (5.54e-2)" "unprognostic (4.87e-3)" "unprognostic (2.24e-2)" "unprognostic (1.72e-1)" "unprognostic (6.41e-2)" "unprognostic (9.59e-2)" "unprognostic (2.93e-3)" "unprognostic (6.20e-2)" "unprognostic (3.26e-2)" "unprognostic (3.70e-2)" "unprognostic (6.40e-2)" "unprognostic (3.43e-1)" "unprognostic (1.50e-1)" 15.0 17.0 17.6 18.2 21.2 31.6 19.7 22.5 19.6 17.5 20.7 25.4 24.5 10.9 24.6 19.6 38.6 14.8 17.0 16.5 16.7 20.7 19.6 15.5 18.8 16.8 21.8 17.3 24.8 19.4 18.7 29.5 16.9 29.1 22.9 17.0 26.2 67.2 21.6 41.6 11.7 13.9 20.4 19.1 20.5 15.9 21.7 14.5 29.7 39.2 16.3 31.5 21.1 31.1 6.7 9.7 23.8 14.5 10.5 8.7 7.1 50.1 20.4 14.2 31.9 12.5 14.0 8.1 25.2 24.5 12.3 12.7 14.8 40.2 24.0 19.6 17.4 25.7 9.4 12.9 14.4 14.5 8.8 17.3 8.7 14.4 22.4 25.0 8.6 21.4 14.4 10.7 17.3 11.2 11.2 16.8 21.2 29.6 22.3 32.4 13.5 25.3 36.5 12.3 6.9 17.6 28.7 4.3 10.7 13.2 10.4 19.7 15.9 19.4 11.4 9.8 9.8 14.0 18.3 14.7 24.4 32.2 9.9 28.9 2.8 19.8 11.7 23.8 8.1 11.9 8.7 6.7 7.0 6.5 9.7 4.2 6.0 6.2 21.4 10.5 14.5 7.3 6.5 7.1 17.6 21.2 22.5 18.0 16.7 20.7 21.8 17.3 29.1 14.5 NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014113-33062797 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010630, HPA029058" Uncertain "Intracellular and membrane" "HPA010630: AB_2668319, HPA029058: AB_10601380" "unprognostic (7.50e-2)" "unprognostic (3.10e-1)" "unprognostic (1.14e-1)" "unprognostic (2.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.56e-2)" "prognostic unfavourable (2.42e-4)" "unprognostic (3.25e-2)" "unprognostic (3.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "prognostic unfavourable (1.70e-4)" "unprognostic (9.37e-2)" "unprognostic (2.05e-1)" "unprognostic (2.12e-3)" "unprognostic (3.43e-3)" 12.3 12.1 9.9 17.0 9.9 15.4 11.4 16.2 12.2 12.0 27.5 7.4 8.1 20.9 14.7 11.6 12.0 9.0 12.9 11.6 9.8 10.3 11.7 10.5 11.6 15.0 10.3 9.8 10.3 19.1 5.5 10.9 10.6 8.4 9.6 27.2 8.5 9.0 8.9 53.3 15.0 19.7 7.5 9.9 18.4 14.5 6.3 8.9 15.4 9.8 28.8 22.8 12.0 11.6 21.4 6.8 36.6 11.4 8.6 18.9 13.3 14.1 10.3 9.6 8.5 7.3 6.4 7.8 15.5 10.1 10.5 14.4 6.4 40.0 35.5 9.0 9.0 21.5 10.4 10.2 15.7 5.5 13.3 16.1 12.2 9.3 7.7 19.2 13.4 7.1 9.1 11.5 23.1 6.9 13.9 9.5 12.9 9.6 7.1 30.1 9.9 9.1 9.5 8.8 21.0 33.6 14.9 10.4 12.9 10.1 19.1 24.2 12.7 10.7 6.0 9.0 8.1 15.3 20.2 19.0 21.6 17.4 7.4 11.9 14.0 26.9 8.0 29.8 9.0 10.2 10.2 21.4 12.1 11.0 6.8 20.5 12.4 10.6 36.6 8.6 11.4 6.4 18.9 13.3 9.9 9.9 16.2 12.2 9.8 10.3 10.3 9.8 8.4 8.9 NT5C3B "cN-IIIB, MGC20781, NT5C3L" ENSG00000141698 "5'-nucleotidase, cytosolic IIIB" Q969T7 17 41825181-41836263 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030786, HPA057095" Approved "HPA030786: AB_10602716, HPA057095: " "unprognostic (3.90e-2)" "unprognostic (5.75e-2)" "unprognostic (8.87e-2)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "prognostic unfavourable (8.11e-5)" "unprognostic (3.40e-2)" "unprognostic (6.05e-2)" "unprognostic (2.31e-1)" "prognostic favourable (2.67e-4)" "unprognostic (3.07e-1)" "unprognostic (7.17e-3)" "unprognostic (2.36e-2)" "unprognostic (4.80e-3)" "unprognostic (7.14e-3)" "unprognostic (1.42e-2)" 10.0 12.4 15.9 8.3 26.2 3.2 18.3 22.8 31.2 11.6 15.6 8.4 10.1 4.4 14.1 21.3 13.9 12.6 11.5 11.4 15.0 14.9 19.2 19.4 11.0 7.9 12.9 16.4 15.5 19.6 21.1 13.7 11.5 13.2 12.6 13.8 12.6 15.9 20.1 7.8 8.6 8.1 22.1 6.7 7.7 12.0 24.8 9.8 1.4 37.8 5.6 10.7 13.3 9.7 5.3 5.2 2.5 5.6 1.0 5.9 4.1 8.6 12.9 22.0 29.0 20.3 17.1 3.1 8.6 25.2 27.6 27.5 10.5 5.0 12.9 4.5 17.6 8.3 21.8 12.2 44.8 6.3 8.6 7.8 13.4 11.1 13.5 0.1 3.2 12.1 11.7 23.3 19.0 15.9 7.3 8.1 19.4 5.0 12.5 3.0 5.9 1.9 10.7 29.3 11.9 12.0 9.3 13.5 6.9 13.0 46.6 4.6 12.6 4.7 10.9 8.5 6.7 14.2 17.7 1.6 6.6 6.3 11.1 0.2 10.4 1.5 5.6 0.5 3.8 1.0 5.8 4.7 5.9 5.1 5.2 5.3 5.4 4.5 2.5 1.0 0.7 2.7 0.8 4.1 15.9 26.2 22.8 31.2 15.0 14.9 12.9 16.4 13.2 9.8 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 108.8;TIME: 63.0;U-87 MG: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 13.4;memory CD8 T-cell: 6.6;naive B-cell: 19.9;naive CD8 T-cell: 17.3" "Group enriched" "Detected in many" 47 "B-cells: 19.9;T-cells: 17.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" 1600000 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavourable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavourable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavourable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 12.2 3.2 9.3 7.7 11.6 0.5 16.6 1.1 6.9 58.8 13.9 3.6 8.1 18.6 33.3 14.8 7.6 12.2 15.4 6.1 5.7 5.5 8.8 26.0 3.4 6.8 6.3 6.6 25.4 1.4 1.6 9.3 42.2 5.3 16.4 15.6 15.3 4.6 17.8 5.7 4.5 14.9 35.3 6.3 7.0 6.0 12.4 4.2 1.6 26.5 7.3 7.1 16.6 20.2 19.9 0.0 0.2 0.0 0.4 17.3 3.9 5.4 2.9 5.0 0.1 11.5 36.7 0.0 35.5 38.9 17.5 32.9 0.0 54.5 0.0 12.8 31.0 2.8 0.0 35.7 41.7 0.0 0.0 0.0 0.8 0.6 5.7 0.0 0.0 9.4 0.4 35.7 22.8 14.5 0.0 0.1 108.8 0.9 0.0 0.0 0.1 3.9 0.1 1.1 0.1 37.9 2.4 0.0 0.6 0.4 2.2 12.0 0.0 0.9 63.0 14.3 0.1 18.0 57.7 2.7 1.7 0.0 98.1 0.0 44.8 0.0 0.0 0.2 2.0 0.0 3.5 13.4 2.3 6.6 0.0 19.9 2.4 17.3 0.2 0.4 0.0 0.0 0.8 3.9 9.3 11.6 1.1 6.9 5.7 5.5 6.3 6.6 5.3 4.2 NT5M "dNT-2, dNT2, mdN" ENSG00000205309 "5',3'-nucleotidase, mitochondrial" Q9NPB1 17 17303335-17347663 "Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 27.1" "Cell line enhanced" "Detected in many" "RPMI-8226: 7.4;SH-SY5Y: 7.1;U-266/70: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 3.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043777 Uncertain "HPA043777: AB_10962842" "unprognostic (5.70e-2)" "unprognostic (3.20e-2)" "unprognostic (1.06e-2)" "unprognostic (2.59e-2)" "unprognostic (8.61e-3)" "unprognostic (1.24e-1)" "unprognostic (1.60e-1)" "unprognostic (1.61e-1)" "unprognostic (2.48e-1)" "prognostic favourable (8.42e-5)" "unprognostic (4.28e-5)" "unprognostic (2.27e-1)" "unprognostic (4.93e-2)" "unprognostic (3.89e-2)" "unprognostic (1.05e-1)" "unprognostic (7.93e-2)" "unprognostic (1.05e-2)" 2.6 1.8 7.2 2.0 7.4 9.4 2.1 8.8 11.8 3.3 2.8 3.7 3.1 2.1 2.8 1.9 2.7 3.0 1.9 6.6 5.8 5.3 3.3 5.5 1.7 1.7 5.5 3.9 3.8 1.9 2.9 5.0 1.5 5.7 3.3 1.4 3.5 2.7 2.7 27.1 2.1 2.2 2.0 4.1 1.7 1.3 7.0 2.0 4.2 1.7 2.4 1.6 2.6 1.7 0.2 0.6 3.6 0.0 0.0 1.5 3.1 0.4 0.9 0.4 3.6 2.2 2.5 1.6 0.7 0.2 0.3 0.6 0.0 0.2 4.2 2.2 0.0 0.0 0.2 0.1 0.0 3.5 2.3 2.7 0.0 0.3 2.2 0.7 5.4 1.8 1.8 0.4 1.4 0.1 2.3 0.0 0.0 1.1 3.4 3.1 2.3 3.2 2.6 0.3 7.4 1.2 0.0 4.5 7.1 1.2 0.2 3.2 1.3 1.0 0.0 1.2 1.3 0.3 1.0 11.5 1.5 0.6 0.6 0.5 2.9 0.0 0.0 3.6 0.1 0.0 1.4 0.0 0.1 1.5 0.6 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 3.1 7.2 7.4 8.8 11.8 5.8 5.3 5.5 3.9 5.7 2.0 NUDT5 "hYSAH1, YSA1H" ENSG00000165609 "Nudix hydrolase 5" Q9UKK9 10 12165325-12196144 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019827 Approved Approved Nucleoplasm,Vesicles,Centrosome 660000 Vesicles "Nucleoplasm, Centrosome" "HPA019827: AB_1854704" "unprognostic (2.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.77e-3)" "unprognostic (4.91e-2)" "unprognostic (2.54e-2)" "unprognostic (4.60e-2)" "unprognostic (1.32e-1)" "unprognostic (6.39e-3)" "unprognostic (2.06e-1)" "unprognostic (9.97e-2)" "prognostic unfavourable (7.14e-12)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (3.12e-2)" "unprognostic (3.68e-2)" 19.6 22.0 17.4 18.6 21.2 13.5 20.2 15.4 21.4 16.7 20.4 16.1 15.2 17.3 10.0 16.5 25.8 16.3 12.1 10.0 16.2 14.3 26.0 57.1 16.8 22.7 21.7 12.8 12.5 16.9 19.1 35.7 19.9 18.5 13.4 24.2 13.2 16.7 19.7 5.1 20.6 15.9 11.6 17.9 22.4 14.1 8.0 21.5 28.2 19.1 16.5 29.5 16.2 18.6 22.4 45.9 50.1 19.5 16.2 37.0 20.4 37.3 27.6 33.0 30.7 32.0 31.6 29.3 27.7 17.7 32.7 35.1 39.6 35.7 37.4 24.1 22.4 37.6 46.0 42.9 30.0 30.6 45.0 31.1 33.9 58.1 33.4 20.6 21.9 33.2 25.6 35.6 18.2 41.6 41.6 25.6 29.7 34.3 38.6 24.2 28.7 17.2 35.3 12.0 43.4 30.5 12.9 15.9 23.9 33.6 25.9 38.5 44.4 21.3 26.0 13.9 26.7 38.8 33.8 21.6 37.9 50.3 29.3 26.9 10.3 8.1 19.1 33.5 22.8 19.5 26.2 22.4 24.6 26.8 27.0 18.3 17.0 23.0 50.1 16.2 14.8 45.9 37.0 20.4 17.4 21.2 15.4 21.4 16.2 14.3 21.7 12.8 18.5 21.5 NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422582-87459454 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" 9000 "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: AB_10696790, HPA044866: , HPA078535: " "unprognostic (7.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.45e-2)" "prognostic favourable (7.43e-5)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-2)" "unprognostic (4.23e-1)" "prognostic favourable (8.00e-11)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-3)" 14.2 25.6 19.5 10.0 22.7 4.0 31.1 22.5 22.3 17.9 19.6 11.8 18.0 27.0 17.3 24.5 12.8 16.2 11.4 18.0 21.8 19.4 28.1 30.9 15.8 12.2 22.9 16.5 18.4 64.1 35.4 33.1 17.5 20.0 22.5 18.3 11.3 20.2 18.7 23.8 10.2 30.0 16.0 17.0 9.9 14.1 14.1 22.6 7.6 22.7 16.0 9.7 13.6 35.9 13.9 13.8 3.7 13.9 9.3 18.3 10.6 10.6 11.5 12.8 6.4 25.4 16.0 10.4 20.5 13.3 7.9 7.9 8.1 18.4 15.6 21.0 16.6 7.3 11.8 14.4 12.7 11.7 9.1 5.1 13.4 14.1 16.0 9.3 8.4 15.4 19.2 9.4 8.9 15.8 14.3 10.5 14.9 14.0 13.0 10.1 10.3 4.7 15.3 11.4 9.1 59.7 9.8 15.5 10.6 13.2 23.4 10.4 13.4 13.5 16.2 12.8 12.4 9.3 10.0 8.1 6.3 12.7 18.4 8.8 16.1 0.9 11.7 3.7 13.4 13.8 12.4 13.9 13.4 13.2 13.8 12.0 15.9 18.3 1.3 9.3 13.9 13.0 12.3 10.6 19.5 22.7 22.5 22.3 21.8 19.4 22.9 16.5 20.0 22.6 PAPD4 "FLJ38499, GLD2, TUT2" ENSG00000164329 "Poly(A) RNA polymerase D4, non-canonical" Q6PIY7 5 79612120-79686648 "Enzymes, Predicted intracellular proteins" "mRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054468 Approved Cytosol Cytosol "HPA054468: " "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.25e-3)" "unprognostic (1.91e-1)" "unprognostic (8.03e-2)" "unprognostic (2.80e-3)" "unprognostic (2.10e-2)" "unprognostic (1.10e-1)" "unprognostic (6.80e-2)" "unprognostic (1.57e-3)" "unprognostic (9.37e-2)" "unprognostic (2.21e-1)" "unprognostic (7.71e-2)" "unprognostic (2.38e-1)" "unprognostic (8.43e-3)" "unprognostic (5.84e-3)" "unprognostic (2.67e-3)" 25.4 21.1 15.8 34.4 22.1 42.1 27.9 20.9 30.3 23.8 22.6 24.7 22.7 19.2 34.4 28.1 22.0 20.7 23.3 16.5 16.5 14.6 20.0 25.3 25.6 34.7 19.4 20.2 29.6 21.4 18.0 23.1 25.7 17.2 20.6 23.3 23.8 21.4 28.3 21.0 25.5 25.4 23.1 22.2 37.4 21.0 26.0 21.2 33.8 24.9 21.3 29.3 22.6 21.9 20.2 19.5 22.3 22.1 19.3 29.9 15.7 11.4 8.0 8.9 14.1 15.7 18.3 14.3 13.9 21.4 16.3 26.1 7.1 13.7 21.5 7.3 15.3 11.0 11.4 15.4 18.7 15.9 10.5 12.2 9.9 11.0 20.4 18.0 16.9 16.1 16.8 11.5 21.6 13.7 13.9 15.9 17.9 6.2 20.5 23.2 8.3 5.7 18.4 9.0 23.9 15.8 16.5 5.9 10.8 11.0 12.1 21.8 10.4 28.6 12.6 8.8 6.0 8.5 15.3 16.7 13.9 21.3 15.6 19.0 12.3 22.3 19.1 18.6 18.2 22.1 29.9 20.2 19.9 19.9 19.5 16.2 19.3 19.8 17.3 19.3 21.7 10.7 20.2 15.7 15.8 22.1 20.9 30.3 16.5 14.6 19.4 20.2 17.2 21.2 PAPD7 "LAK-1, POLK, POLS, TRF4, TRF4-1" ENSG00000112941 "Poly(A) RNA polymerase D7, non-canonical" Q5XG87 5 6713007-6757048 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045487, HPA046742" Enhanced Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus" Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA045487: AB_2679346, HPA046742: AB_2679781" "unprognostic (1.45e-1)" "unprognostic (2.96e-1)" "unprognostic (2.08e-2)" "unprognostic (2.12e-3)" "unprognostic (7.57e-2)" "unprognostic (1.30e-2)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.62e-1)" "unprognostic (9.78e-2)" "unprognostic (3.10e-3)" "unprognostic (3.73e-2)" "prognostic unfavourable (7.99e-5)" "unprognostic (6.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.60e-2)" "prognostic favourable (8.55e-4)" 13.5 7.9 9.6 13.9 11.1 25.8 16.3 22.7 12.3 15.1 16.6 10.6 14.8 9.5 13.2 8.0 12.2 11.3 11.4 8.6 10.7 7.3 9.7 19.9 13.2 14.1 14.8 5.8 18.5 13.3 13.2 12.2 10.0 9.0 11.6 8.3 10.2 17.0 10.6 10.4 16.7 13.1 13.9 7.9 14.8 10.1 11.1 11.7 25.4 11.3 11.3 11.6 12.5 34.9 1.9 3.8 0.7 0.7 0.5 2.3 0.8 16.3 11.1 13.7 16.8 9.9 8.9 19.7 11.1 14.0 13.9 15.8 11.5 9.1 12.0 8.6 13.7 12.2 11.1 8.6 12.8 13.4 7.1 6.1 35.1 6.2 6.2 9.2 9.3 6.0 7.5 15.5 10.0 8.1 8.2 15.9 11.3 9.0 12.5 12.0 7.4 8.7 11.3 11.6 3.0 5.5 9.4 13.6 10.4 26.6 12.9 7.6 7.8 5.1 7.1 16.7 17.5 14.6 15.5 15.2 6.3 10.6 10.8 8.6 10.3 0.0 0.7 0.7 2.1 0.4 2.3 1.9 1.7 1.6 1.2 1.5 1.9 1.7 0.4 0.5 0.6 3.8 1.8 0.8 9.6 11.1 22.7 12.3 10.7 7.3 14.8 5.8 9.0 11.7 PAPOLA PAP ENSG00000090060 "Poly(A) polymerase alpha" P51003 14 96501433-96567111 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001788 Supported Supported Nucleoplasm Nucleoplasm "HPA001788: AB_1079564" "unprognostic (3.18e-1)" "unprognostic (1.30e-1)" "unprognostic (9.69e-2)" "unprognostic (7.26e-2)" "unprognostic (9.10e-2)" "unprognostic (5.10e-3)" "prognostic unfavourable (2.41e-5)" "unprognostic (2.12e-2)" "unprognostic (2.82e-2)" "unprognostic (1.38e-3)" "unprognostic (3.13e-1)" "unprognostic (1.22e-3)" "unprognostic (3.37e-1)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (1.08e-2)" "unprognostic (4.05e-1)" 35.8 43.4 49.1 45.7 51.6 54.5 39.7 61.2 60.5 41.0 45.1 25.2 45.6 34.9 43.8 48.3 42.0 38.7 35.6 71.8 46.3 39.6 40.0 50.2 37.1 44.7 48.1 39.7 58.2 52.9 50.2 68.7 54.5 45.6 45.1 45.8 24.0 39.2 45.5 46.4 35.5 45.5 38.9 41.9 50.9 40.4 53.0 55.7 53.0 54.8 34.8 49.6 44.9 119.5 26.4 23.0 39.0 23.5 25.2 23.4 19.8 32.0 31.0 39.9 40.0 28.9 32.7 90.8 29.4 31.8 35.0 33.7 35.8 33.2 43.5 33.9 34.4 27.8 13.0 40.5 62.8 35.9 21.1 35.1 23.5 35.1 29.9 45.9 35.6 29.8 35.5 39.1 35.0 39.1 32.9 39.9 33.7 46.7 35.9 23.3 27.2 35.3 38.4 48.6 25.2 34.9 51.2 41.0 27.2 39.2 30.8 28.6 43.7 40.4 31.1 24.7 19.7 27.8 35.8 31.5 47.1 38.4 40.0 35.2 41.4 39.0 19.7 32.7 15.5 23.5 20.4 23.8 19.6 22.6 23.0 26.4 23.4 21.8 27.4 25.2 22.6 15.2 18.7 19.8 49.1 51.6 61.2 60.5 46.3 39.6 48.1 39.7 45.6 55.7 PAPOLB PAPT ENSG00000218823 "Poly(A) polymerase beta" Q9NRJ5 7 4857733-4861994 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 33.0" "Cell line enhanced" "Detected in single" "THP-1: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (7.58e-2)" "unprognostic (1.25e-1)" "unprognostic (1.68e-2)" "unprognostic (1.78e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.5 0.1 PAPOLG FLJ12972 ENSG00000115421 "Poly(A) polymerase gamma" Q9BWT3 2 60756230-60802085 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017795, HPA035349, HPA035350" Approved Enhanced Nucleoplasm Nucleoplasm "CAB017795: , HPA035349: , HPA035350: " "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (3.39e-2)" "unprognostic (5.56e-2)" "unprognostic (3.54e-1)" "unprognostic (6.72e-4)" "unprognostic (2.49e-1)" "unprognostic (6.97e-3)" "unprognostic (6.83e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-1)" "prognostic unfavourable (4.21e-4)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (2.62e-2)" 12.3 9.5 11.6 11.6 11.9 5.8 9.9 19.4 15.3 10.2 8.2 9.8 7.8 6.8 12.1 6.2 10.1 9.0 10.2 8.5 15.1 10.1 8.6 6.9 9.4 14.8 10.9 11.3 17.1 9.9 13.3 18.9 11.8 12.5 9.6 9.2 7.7 11.1 8.7 13.1 11.7 9.7 9.9 21.0 15.0 9.1 14.2 11.0 23.1 27.5 6.6 14.3 10.9 11.1 6.1 3.7 13.2 6.9 9.4 9.7 4.1 5.1 4.8 9.0 7.3 11.6 8.7 8.6 5.7 5.6 4.9 5.2 8.1 4.4 7.4 6.0 4.4 8.7 12.7 5.4 9.2 12.8 6.8 9.4 4.7 5.7 7.0 9.8 6.5 6.5 6.4 5.9 12.4 7.8 9.2 7.0 5.4 4.1 11.3 6.7 14.3 4.4 9.3 16.0 6.6 5.3 4.9 5.3 7.4 9.1 5.7 5.1 3.8 6.0 7.3 6.3 7.6 4.7 5.3 7.0 4.1 18.0 5.1 11.2 4.5 13.2 4.1 8.7 6.7 4.3 8.3 5.9 7.2 6.0 3.7 6.1 7.9 7.3 10.6 9.4 6.9 3.3 9.7 4.1 11.6 11.9 19.4 15.3 15.1 10.1 10.9 11.3 12.5 11.0 PAPSS1 "ATPSK1, PAPSS" ENSG00000138801 "3'-phosphoadenosine 5'-phosphosulfate synthase 1" O43252 4 107590276-107720452 "Enzymes, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 50.3;eosinophil: 62.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 62.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049781 Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA049781: " "unprognostic (1.36e-2)" "unprognostic (5.03e-2)" "prognostic favourable (9.14e-4)" "prognostic favourable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "prognostic unfavourable (2.70e-5)" "unprognostic (1.58e-2)" "unprognostic (1.05e-1)" "unprognostic (8.92e-2)" "unprognostic (1.42e-1)" "unprognostic (5.76e-2)" "unprognostic (6.23e-3)" "unprognostic (1.29e-1)" "unprognostic (1.72e-1)" "unprognostic (1.61e-2)" "unprognostic (1.38e-1)" 13.5 7.4 24.3 14.4 28.5 11.1 25.2 16.4 32.2 26.6 10.0 45.0 9.4 7.9 25.1 22.8 18.3 24.9 13.3 7.7 31.3 23.9 16.7 5.1 22.0 14.7 29.7 21.9 15.6 24.6 15.6 15.5 8.5 38.2 21.7 12.7 9.5 32.2 14.0 3.3 24.5 8.5 17.0 59.9 9.6 30.4 8.1 25.5 14.7 10.3 11.0 24.6 16.5 13.7 8.5 9.2 62.2 10.2 4.6 6.8 5.8 10.5 9.6 16.3 20.4 20.2 25.5 13.1 13.4 25.4 13.2 17.7 14.7 15.3 16.5 8.6 24.7 13.3 15.4 26.6 17.0 38.7 11.7 19.2 20.9 32.9 11.1 29.1 33.3 21.1 13.8 15.2 12.5 29.2 4.2 32.1 36.9 16.1 23.4 9.0 17.5 10.7 19.7 25.9 4.7 19.8 14.7 18.6 26.9 13.9 21.1 16.4 12.5 4.5 17.2 16.5 17.0 11.0 11.3 25.8 17.1 15.4 20.1 22.3 25.9 50.3 8.9 62.2 3.0 9.6 3.5 8.5 4.0 3.4 9.2 4.1 2.5 2.9 9.4 4.6 10.2 1.8 6.8 5.8 24.3 28.5 16.4 32.2 31.3 23.9 29.7 21.9 38.2 25.5 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.2;liver: 49.0" "Cell line enhanced" "Detected in many" "BJ: 34.9;fHDF/TERT166: 88.3;HHSteC: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 5.3;myeloid DC: 2.7;non-classical monocyte: 9.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.7;monocytes: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria Mitochondria "HPA071224: , HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavourable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favourable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavourable (3.21e-5)" "unprognostic (3.46e-3)" 16.0 59.2 3.5 18.1 6.0 0.3 18.1 1.9 4.3 8.6 25.5 2.2 1.9 9.2 4.0 7.0 3.7 5.3 10.7 9.1 3.9 2.1 9.9 49.0 31.3 15.6 4.4 1.6 10.8 21.2 0.4 1.7 19.0 5.2 3.8 21.2 6.2 6.2 2.0 4.8 1.7 19.4 5.5 3.4 2.9 2.9 3.6 4.3 0.8 7.3 6.2 11.0 5.7 5.3 0.0 2.7 0.8 9.7 0.0 0.1 0.8 3.5 3.6 1.1 0.0 25.3 32.3 0.0 34.9 29.9 21.2 15.4 0.1 0.7 0.0 1.8 88.3 1.5 2.6 2.4 24.3 0.0 1.9 1.6 2.6 0.0 38.3 0.0 0.7 11.4 0.0 12.2 1.0 17.7 0.0 16.5 14.9 13.3 0.0 0.1 1.3 4.5 0.0 0.0 0.0 22.1 1.5 0.1 0.3 17.0 0.6 0.2 2.5 0.9 22.0 7.2 4.2 24.4 2.5 0.0 0.1 0.0 3.4 0.0 0.0 0.0 1.4 0.0 0.0 5.3 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.8 0.0 9.7 0.0 0.0 0.8 3.5 6.0 1.9 4.3 3.9 2.1 4.4 1.6 5.2 4.3 PDE10A ENSG00000112541 "Phosphodiesterase 10A" Q9Y233 6 165327287-165986603 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.8" "Cell line enhanced" "Detected in some" "LHCN-M2: 13.7;RH-30: 8.0;RT4: 8.4;SH-SY5Y: 8.4;TIME: 14.2;U-2 OS: 7.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 36.8" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 11 "basal ganglia: 307.0" "Group enriched" "Detected in all" 4 "basal ganglia: 155.2;cerebellum: 80.7" "CAB045998, HPA047200" Supported "CAB045998: AB_2162589, HPA047200: " "unprognostic (1.02e-1)" "unprognostic (3.63e-2)" "unprognostic (3.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (6.03e-2)" "unprognostic (3.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavourable (4.44e-7)" "unprognostic (3.59e-3)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (5.90e-3)" 3.1 1.9 1.7 1.0 36.8 0.0 3.4 4.5 6.9 2.2 1.0 1.1 4.3 0.8 2.9 7.5 0.7 3.1 3.2 3.6 2.6 2.1 8.8 0.9 4.3 1.4 2.7 1.1 3.4 0.8 1.2 2.5 5.3 1.7 2.6 0.5 0.6 0.7 4.9 0.9 0.6 0.8 4.3 1.1 2.5 1.2 8.7 16.0 0.0 12.2 1.0 0.8 7.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.7 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.3 0.0 7.6 0.0 0.5 0.0 0.0 0.1 0.0 0.6 0.0 7.4 0.0 0.0 13.7 0.1 1.1 0.0 1.5 5.5 1.7 8.0 0.0 7.2 8.4 2.2 8.4 0.0 0.0 0.4 0.0 0.0 14.2 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 36.8 4.5 6.9 2.6 2.1 2.7 1.1 1.7 16.0 PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623252-178072755 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 20.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.7;fHDF/TERT166: 5.5;HAP1: 3.1;Hep G2: 6.2" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA034560 Approved "Intracellular and membrane" "HPA034560: AB_10602140" "unprognostic (1.02e-1)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.61e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.91e-1)" "unprognostic (9.95e-2)" "unprognostic (2.80e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-4)" "unprognostic (1.64e-3)" 2.9 0.5 1.3 0.7 1.0 0.2 2.5 0.2 0.8 4.2 3.1 0.1 0.0 1.2 1.9 1.5 0.3 0.4 5.4 2.6 1.6 2.0 4.0 11.8 0.5 0.0 3.3 0.0 0.5 7.8 9.8 13.6 0.0 1.2 20.8 0.5 5.6 8.5 1.2 7.5 0.3 7.6 1.7 5.6 0.1 0.4 3.8 0.0 0.1 13.2 0.7 0.1 0.6 0.3 1.0 0.8 2.2 0.9 0.9 0.7 0.2 0.1 1.0 0.5 0.2 0.2 0.0 0.2 2.5 0.4 0.1 0.8 0.5 3.7 0.1 1.5 5.5 0.2 3.1 0.1 0.1 0.0 2.0 2.4 0.2 6.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.9 0.3 1.2 0.1 0.5 0.1 0.5 0.0 1.1 0.1 0.7 1.7 0.0 0.2 0.4 0.3 0.0 0.0 0.3 0.6 0.2 0.3 0.5 0.0 0.0 1.0 0.1 0.2 1.6 0.7 1.1 0.7 0.6 0.5 0.7 0.6 0.7 0.4 1.0 0.6 0.7 2.2 0.9 0.9 0.8 0.7 0.2 1.3 1.0 0.2 0.7 1.6 2.0 3.3 0.0 1.2 0.0 PDE1A ENSG00000115252 "Phosphodiesterase 1A" P54750 2 182140036-182523192 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 66.0;kidney: 37.1" "Group enriched" "Detected in some" 5 "ASC diff: 22.3;HHSteC: 13.2;HSkMC: 28.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 1.4" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 6 "amygdala: 118.0;basal ganglia: 76.2;cerebral cortex: 161.5;hippocampal formation: 155.8;hypothalamus: 47.8" "Low region specificity" "Detected in many" HPA022151 Approved Approved Nucleoplasm Nucleoplasm "HPA022151: AB_1855118" "unprognostic (3.63e-1)" "unprognostic (7.21e-2)" "unprognostic (1.32e-1)" "unprognostic (8.61e-2)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (3.84e-1)" "unprognostic (3.82e-1)" "unprognostic (1.02e-1)" "unprognostic (5.38e-2)" "unprognostic (2.78e-1)" "unprognostic (2.86e-1)" "unprognostic (5.55e-3)" "unprognostic (2.50e-3)" "unprognostic (5.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.40e-3)" 7.6 3.9 13.8 3.6 11.5 0.5 4.1 66.0 25.3 11.5 8.8 6.2 1.7 2.6 7.3 6.7 4.7 7.4 18.2 11.8 12.6 4.1 37.1 3.2 3.1 1.8 7.1 15.7 9.2 2.0 1.3 2.3 1.3 6.9 3.8 5.6 3.0 1.8 4.8 2.4 2.1 4.6 11.8 10.1 2.6 4.6 24.6 9.0 0.0 35.1 2.6 1.1 8.3 9.0 0.0 1.4 0.8 0.2 0.0 0.0 0.0 0.0 0.1 2.2 0.0 22.3 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 0.0 3.1 0.0 13.2 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 4.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 3.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 13.8 11.5 66.0 25.3 12.6 4.1 7.1 15.7 6.9 9.0 PDE1B PDES1B ENSG00000123360 "Phosphodiesterase 1B" Q01064 12 54549350-54579239 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 52.6" "Cell line enhanced" "Detected in some" "HDLM-2: 11.3;HL-60: 6.3;HMC-1: 12.1;NB-4: 8.0;THP-1: 7.7;U-937: 6.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 52.6" "Cell type enriched" "Detected in single" 4 "naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 4 "T-cells: 1.6" "Region enriched" "Detected in all" 6 "basal ganglia: 895.2" "Region enriched" "Detected in all" 7 "basal ganglia: 253.8" HPA018492 Enhanced "HPA018492: AB_1855119" "unprognostic (2.90e-1)" "unprognostic (1.51e-1)" "unprognostic (7.67e-4)" "unprognostic (5.63e-3)" "unprognostic (7.02e-2)" "unprognostic (7.51e-2)" "unprognostic (1.97e-1)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "unprognostic (5.11e-2)" "unprognostic (3.84e-3)" "unprognostic (2.70e-2)" "prognostic unfavourable (4.77e-6)" "unprognostic (6.64e-4)" "unprognostic (2.14e-1)" "unprognostic (3.09e-1)" "unprognostic (2.83e-2)" 12.3 1.4 9.9 4.6 52.6 5.6 2.7 3.1 19.4 2.6 3.7 1.4 0.0 1.2 3.9 2.5 1.7 2.4 2.9 1.9 3.7 3.8 1.3 1.6 2.9 1.6 3.0 9.3 12.5 0.6 11.0 0.5 0.5 5.8 1.0 1.7 0.5 1.3 2.1 0.7 1.0 2.6 4.9 1.2 4.8 2.5 1.1 7.7 0.0 2.7 0.0 1.1 2.8 1.1 0.2 0.3 0.1 0.3 0.1 1.6 0.4 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.1 0.0 0.0 1.8 0.0 0.0 11.3 0.3 4.6 0.0 0.0 0.0 6.3 12.1 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.7 8.0 3.3 0.0 2.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.4 0.0 6.4 1.2 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.2 1.6 0.0 0.1 0.1 0.0 0.0 0.0 0.4 9.9 52.6 3.1 19.4 3.7 3.8 3.0 9.3 5.8 7.7 PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32299329 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease mutation, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.6;heart muscle: 56.2" "Cell line enhanced" "Detected in some" "BJ: 15.0;fHDF/TERT166: 48.3;U-251 MG: 26.1;WM-115: 34.5" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm Nucleoplasm "HPA052375: " "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" 2.9 2.7 10.6 3.2 27.7 0.9 5.1 2.4 17.1 1.2 2.7 30.1 0.0 2.3 3.1 6.8 7.4 8.4 2.4 56.2 14.8 7.5 4.0 1.0 5.0 1.4 31.1 12.0 4.9 2.7 1.3 1.3 4.0 16.3 2.9 2.7 7.9 2.6 4.2 1.4 0.9 2.8 10.4 17.1 1.4 3.8 4.2 33.6 0.0 3.9 0.2 1.0 7.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 5.2 0.0 0.2 0.1 0.0 15.0 6.1 7.1 5.8 0.0 0.0 0.0 0.0 48.3 0.4 0.0 0.0 9.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 10.8 0.6 0.0 1.4 0.0 2.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 7.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 2.9 0.1 26.1 0.0 0.0 0.0 0.7 0.1 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 27.7 2.4 17.1 14.8 7.5 31.1 12.0 16.3 33.6 PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.0;lymphoid tissue: 65.4" "Cell line enriched" "Detected in some" 8 "HeLa: 105.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 30.4;basal ganglia: 34.2;cerebral cortex: 48.0;hippocampal formation: 18.0;olfactory region: 27.0" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.7;T-cells: 9.6" "Group enriched" "Detected in many" 5 "amygdala: 111.5;basal ganglia: 166.3;cerebral cortex: 98.9;hippocampal formation: 120.9" "CAB009752, HPA031192" Enhanced Supported Cytosol Cytosol "CAB009752: AB_2268159, HPA031192: " "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favourable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" 27.8 18.4 30.4 3.0 34.2 2.5 25.4 1.0 48.0 8.9 7.7 3.8 1.9 3.5 9.4 4.9 10.2 11.6 12.0 11.3 18.0 6.1 7.0 10.4 5.1 3.8 3.8 27.0 3.4 2.4 4.4 3.4 6.6 6.7 4.8 5.2 3.0 2.3 6.3 6.6 4.8 4.2 10.3 2.1 65.4 4.2 2.9 7.4 0.1 7.0 3.9 2.2 8.3 11.2 3.7 1.2 0.2 1.0 0.1 9.6 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 2.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 105.0 0.1 0.2 0.0 1.6 0.0 0.2 0.5 4.3 2.3 0.1 0.1 0.0 0.0 0.0 0.0 1.5 2.9 0.0 0.0 0.2 0.0 0.0 9.4 0.5 0.0 0.0 0.4 0.0 0.0 13.4 0.0 2.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.8 0.0 9.6 1.0 5.6 3.7 5.7 5.6 1.2 2.5 3.7 3.0 0.2 0.1 0.5 0.0 2.3 1.9 30.4 34.2 1.0 48.0 18.0 6.1 3.8 27.0 6.7 7.4 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20369245-20684381 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.2" "Cell line enhanced" "Detected in some" "AF22: 7.7;HEL: 14.2;HeLa: 38.7;HUVEC TERT2: 6.9;SH-SY5Y: 14.5;U-138 MG: 11.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 35.4" "HPA014492, HPA074258" Uncertain Approved "Plasma membrane" 23000 "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavourable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 7.1 1.0 1.7 4.7 2.0 0.0 3.8 3.5 1.4 7.8 15.9 1.0 2.0 2.1 7.8 3.5 9.1 4.9 5.5 62.2 1.6 1.4 3.7 1.8 3.9 3.3 1.9 1.1 7.1 6.5 1.0 2.8 13.8 2.7 6.3 9.0 12.0 7.8 4.2 2.0 1.4 21.4 6.0 1.8 2.1 5.5 2.3 0.7 0.0 2.8 1.9 0.9 4.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 7.7 0.0 1.8 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.2 38.7 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.1 0.0 0.0 0.0 2.1 0.0 0.1 14.5 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.7 2.0 3.5 1.4 1.6 1.4 1.9 1.1 2.7 0.7 PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643723-14872044 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 42.6" "Cell line enhanced" "Detected in many" "HL-60: 13.3;Karpas-707: 15.4;THP-1: 16.3;U-266/70: 17.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 19.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 5.0;T-cells: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA056111: " "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.76e-3)" "unprognostic (4.25e-1)" "unprognostic (1.84e-3)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "prognostic favourable (7.91e-4)" "unprognostic (1.77e-1)" "unprognostic (2.33e-2)" "unprognostic (1.39e-2)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-3)" 42.6 1.0 2.3 12.6 2.2 6.7 17.0 19.2 3.0 2.9 21.8 0.9 0.8 2.2 0.9 1.4 2.6 1.0 6.9 4.7 2.2 2.1 2.4 18.2 10.2 14.1 1.6 1.6 0.9 7.3 0.3 5.1 5.5 1.5 10.7 8.1 1.9 16.5 1.3 0.8 0.9 6.3 9.7 2.1 8.7 3.0 12.5 0.8 7.8 1.2 2.3 7.1 10.5 4.5 0.3 0.4 5.0 1.2 0.1 8.7 1.8 0.0 1.5 3.3 5.4 6.6 0.0 1.3 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.1 11.1 0.1 8.1 10.0 2.3 13.3 0.0 0.5 0.0 0.0 0.3 0.0 11.7 15.4 0.0 0.1 2.6 6.5 4.5 2.4 6.4 1.5 10.0 0.0 1.1 5.1 9.5 1.3 8.6 2.9 0.0 16.3 0.0 0.0 0.8 0.0 0.0 17.4 5.3 0.4 0.1 2.3 1.0 0.0 0.7 2.9 1.4 0.7 2.9 0.3 4.2 3.2 0.4 0.2 8.7 7.5 5.0 0.1 1.2 0.1 4.2 1.8 2.3 2.2 19.2 3.0 2.2 2.1 1.6 1.6 1.5 0.8 PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469631 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5;testis: 31.8" "Cell line enhanced" "Detected in many" "HMC-1: 21.6;NB-4: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Plasma membrane" "Plasma membrane" "CAB017632: AB_1127109, HPA043310: , HPA076091: " "unprognostic (1.29e-2)" "unprognostic (3.98e-2)" "unprognostic (8.91e-2)" "unprognostic (1.82e-1)" "unprognostic (7.00e-2)" "unprognostic (6.84e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-2)" "unprognostic (6.90e-2)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (1.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.15e-1)" 6.4 2.5 9.0 4.2 13.9 3.4 6.3 15.0 38.5 8.4 4.3 3.2 0.4 2.0 4.4 1.1 3.1 4.8 5.0 4.1 12.4 6.9 2.8 1.9 7.7 2.0 5.3 19.4 1.7 9.8 17.3 2.3 4.9 34.7 3.7 3.0 3.1 7.1 4.0 26.1 2.2 2.7 4.7 3.6 4.1 6.1 31.8 4.5 0.0 5.4 1.0 1.9 4.6 3.5 0.2 3.3 5.9 4.4 5.3 2.0 1.3 0.0 1.4 0.3 3.9 11.4 6.8 2.2 3.2 6.5 0.4 1.1 3.4 3.1 1.4 9.6 8.4 0.3 2.2 0.4 0.2 3.7 3.2 13.4 4.7 3.7 7.4 2.2 21.6 5.0 0.4 3.6 0.0 3.1 10.5 3.2 2.3 0.9 1.3 24.9 1.7 2.8 8.8 2.2 11.5 0.5 0.8 2.5 0.9 0.2 0.1 3.5 0.5 4.4 6.5 4.9 6.3 3.3 2.0 6.4 0.5 7.1 2.1 0.1 3.9 5.9 2.6 5.1 1.5 4.4 0.8 0.2 0.5 2.0 3.3 0.1 0.1 0.7 0.2 5.3 4.4 0.2 1.2 1.3 9.0 13.9 15.0 38.5 12.4 6.9 5.3 19.4 34.7 4.5 PDE4B DPDE4 ENSG00000184588 "Phosphodiesterase 4B" Q07343 1 65792514-66374579 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.2" "Cell line enhanced" "Detected in many" "AN3-CA: 23.9;HUVEC TERT2: 35.9;NTERA-2: 21.8;SK-MEL-30: 21.6;TIME: 20.0;U-266/84: 18.8" "Cancer enhanced" "Detected in all" "glioma: 18.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 36.6" "Group enriched" "Detected in all" 5 "B-cells: 16.1;granulocytes: 36.6;T-cells: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003005 Uncertain Approved "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA003005: AB_1079587" "unprognostic (7.86e-2)" "unprognostic (3.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.90e-1)" "unprognostic (3.21e-1)" "unprognostic (3.33e-3)" "unprognostic (1.35e-1)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (6.10e-2)" "unprognostic (8.78e-2)" "unprognostic (4.24e-2)" "prognostic unfavourable (5.04e-4)" "unprognostic (2.89e-2)" "unprognostic (3.54e-1)" "unprognostic (9.04e-3)" "unprognostic (8.33e-3)" 14.9 2.9 21.5 28.4 29.0 48.2 15.0 12.7 31.9 6.4 6.6 39.2 0.7 3.9 6.7 2.1 3.9 3.5 8.1 16.1 20.7 18.8 3.7 8.7 10.0 15.9 36.3 14.2 2.0 1.7 1.7 3.4 13.1 32.2 18.3 8.6 6.6 15.9 10.3 28.2 6.2 8.5 9.5 37.4 18.5 4.2 3.2 36.9 2.3 5.5 5.5 14.7 16.1 3.9 16.1 2.6 36.6 2.8 4.4 13.3 3.7 0.0 6.8 13.5 23.9 0.7 0.7 0.0 4.4 5.2 4.2 5.5 0.0 0.0 2.0 0.1 8.2 0.0 0.1 0.0 4.1 5.8 0.0 0.1 1.9 0.0 0.5 4.8 0.0 1.4 0.2 2.1 0.1 35.9 0.0 1.3 1.8 0.1 0.0 2.8 21.8 0.3 0.9 2.4 1.3 3.3 0.0 0.1 10.4 0.0 1.1 21.6 0.1 1.7 20.0 3.3 0.8 1.8 0.7 0.6 18.8 7.3 3.4 5.0 1.4 2.7 2.8 8.4 4.4 2.4 8.4 15.4 8.3 6.2 2.4 16.1 9.4 6.5 36.6 4.4 2.1 2.6 13.3 3.7 21.5 29.0 12.7 24.6 20.7 18.8 36.3 14.2 32.2 36.9 PDE4C DPDE1 ENSG00000105650 "Phosphodiesterase 4C" Q08493 19 18208652-18248200 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 28.6" "Cell line enhanced" "Detected in some" "BEWO: 5.9;Hep G2: 3.9;U-87 MG: 8.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA048975 Approved "HPA048975: " "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (5.22e-4)" "unprognostic (1.44e-2)" "unprognostic (7.70e-2)" "unprognostic (1.15e-1)" "unprognostic (4.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-3)" "unprognostic (2.21e-1)" "unprognostic (7.25e-10)" "unprognostic (2.73e-2)" "unprognostic (2.65e-1)" "unprognostic (9.21e-2)" "unprognostic (2.45e-2)" 2.0 1.3 1.8 1.5 2.8 1.0 2.0 0.8 6.1 4.1 4.4 1.5 3.1 1.5 6.4 6.8 1.3 4.2 5.6 4.2 1.6 1.9 4.1 2.0 4.1 0.5 1.7 5.1 2.0 0.8 0.3 3.5 7.0 2.8 5.8 1.3 2.5 1.3 5.4 13.4 0.6 4.1 3.4 0.7 2.3 5.2 2.6 1.1 0.4 1.2 28.6 0.7 1.8 3.3 1.3 0.6 3.5 0.7 1.0 0.7 0.2 0.1 0.3 0.2 0.3 0.1 0.3 5.9 0.1 0.0 0.2 0.3 1.2 0.2 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.4 3.9 0.2 0.2 0.5 0.7 0.1 2.5 0.0 0.0 0.9 2.0 0.1 0.4 0.2 0.3 0.1 0.2 0.2 0.3 0.4 0.1 0.2 0.2 0.8 0.3 0.5 0.0 0.5 0.3 0.0 0.4 0.2 0.7 0.1 1.3 0.6 0.2 8.8 0.2 0.3 3.4 0.7 1.0 0.6 0.4 0.5 0.5 0.5 0.4 0.2 1.3 0.5 0.7 3.5 1.0 0.4 0.6 0.3 0.2 1.8 2.8 0.8 6.1 1.6 1.9 1.7 5.1 2.8 1.1 PDE4D DPDE3 ENSG00000113448 "Phosphodiesterase 4D" Q08499 5 58969038-60522120 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.0" "Cell line enhanced" "Detected in many" "A549: 24.8;AN3-CA: 28.5;HeLa: 41.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "eosinophil: 28.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045895 Approved Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA045895: AB_10960275" "unprognostic (1.14e-1)" "unprognostic (8.73e-3)" "unprognostic (4.35e-2)" "unprognostic (7.87e-2)" "unprognostic (5.97e-2)" "unprognostic (2.03e-1)" "unprognostic (8.10e-4)" "unprognostic (1.17e-1)" "unprognostic (6.59e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "prognostic favourable (4.00e-5)" "unprognostic (1.51e-1)" "unprognostic (8.20e-2)" "unprognostic (1.77e-2)" "unprognostic (2.56e-2)" 8.2 1.9 4.4 6.8 8.6 46.2 5.3 4.2 13.0 13.5 18.6 1.4 14.7 4.1 17.1 14.0 10.3 6.6 12.7 15.5 4.5 5.8 12.8 3.4 11.1 3.7 5.2 6.6 5.3 2.9 7.0 9.0 11.8 2.7 18.2 11.2 8.6 24.4 16.5 60.0 5.1 7.5 35.8 5.0 3.8 10.2 2.6 2.8 4.4 6.2 11.3 9.5 20.0 11.2 6.1 0.7 28.1 1.1 0.1 0.8 0.5 0.0 24.8 5.2 28.5 0.9 1.8 4.1 0.6 0.7 1.4 2.0 9.7 0.8 1.9 0.1 0.2 4.2 0.0 1.1 2.4 1.1 2.8 3.6 41.0 2.1 3.8 1.7 0.2 3.8 0.9 3.9 0.7 2.9 0.0 0.6 2.4 1.7 1.3 4.0 0.9 1.3 0.4 6.5 4.1 6.5 9.3 0.9 3.3 6.5 11.0 5.6 0.8 3.7 3.4 0.3 0.1 4.9 1.3 1.4 0.0 0.2 4.2 6.8 1.1 2.0 1.1 28.1 0.8 0.0 0.8 6.1 0.7 0.3 0.7 6.1 0.5 0.4 1.5 0.1 0.1 0.0 0.4 0.5 4.4 8.6 4.2 13.0 4.5 5.8 5.2 6.6 2.7 2.8 PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494395-119628991 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.3;HHSteC: 35.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved "Centriolar satellite,Cytosol" 3100000 Cytosol "Centriolar satellite" "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favourable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavourable (1.17e-4)" 12.3 4.9 2.0 28.2 2.3 0.4 8.1 3.0 2.3 21.3 28.0 1.7 20.1 6.5 17.3 21.4 30.7 10.7 13.3 5.3 2.0 2.8 3.8 1.2 11.4 4.1 2.4 3.4 10.0 7.8 5.1 3.4 8.9 4.4 31.8 11.7 20.2 8.5 23.7 6.8 4.2 15.6 45.6 2.0 2.1 9.1 7.6 1.2 0.9 9.1 8.1 2.2 25.9 15.9 1.5 0.5 1.4 0.4 0.6 2.1 4.2 8.0 0.4 5.7 0.6 1.9 2.9 1.0 5.4 24.3 0.2 0.5 0.5 0.7 0.8 0.2 6.7 2.9 1.8 0.8 0.7 0.2 3.7 9.0 1.4 0.4 35.0 1.9 0.9 3.2 1.7 0.6 0.0 0.7 1.0 1.5 0.8 0.4 2.4 0.3 1.2 1.4 0.3 2.9 2.1 2.1 2.4 2.2 4.5 6.3 7.9 0.6 1.4 1.0 1.2 3.2 2.8 1.7 0.7 2.1 1.0 0.7 3.1 0.5 0.4 0.0 0.3 0.0 0.6 0.1 2.1 1.5 1.3 0.4 0.2 1.0 0.6 0.9 1.4 0.6 0.4 0.5 0.4 4.2 2.0 2.3 3.0 2.3 2.0 2.8 2.4 3.4 4.4 1.2 PDE6A "PDEA, RP43" ENSG00000132915 "Phosphodiesterase 6A" P16499 5 149857955-149944793 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 153.4" "Cell line enriched" "Detected in some" 4 "CACO-2: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016970, HPA074677" Enhanced "HPA016970: AB_1855125, HPA074677: AB_2732264" "unprognostic (6.85e-2)" "unprognostic (8.84e-2)" "unprognostic (1.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (4.39e-3)" "unprognostic (8.83e-2)" "unprognostic (6.54e-2)" "unprognostic (5.91e-3)" "unprognostic (1.77e-2)" "unprognostic (9.21e-2)" "unprognostic (7.57e-5)" "unprognostic (9.93e-2)" "unprognostic (3.08e-1)" "unprognostic (1.31e-1)" "unprognostic (2.26e-2)" 0.2 2.3 0.2 0.2 0.2 0.9 0.2 0.3 0.2 0.2 1.8 0.2 0.3 0.2 0.2 20.1 2.4 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 4.6 0.2 0.2 0.2 1.0 153.4 1.4 0.2 0.2 1.6 0.2 0.2 0.2 0.2 0.1 3.1 0.2 0.2 0.4 0.3 0.5 0.2 0.2 1.5 0.8 3.3 0.8 1.2 0.8 0.1 0.4 0.7 0.6 0.5 0.3 0.3 0.6 0.3 0.1 0.4 0.1 7.4 0.8 0.9 1.3 0.2 0.7 0.2 0.4 0.5 0.6 0.3 1.0 1.1 0.6 0.2 0.7 0.6 0.3 1.1 0.9 0.6 0.2 0.3 1.4 1.4 0.3 0.4 0.9 0.5 0.5 0.3 0.8 0.7 0.5 0.9 0.8 1.1 0.0 0.7 0.2 1.0 0.5 1.4 0.8 1.6 0.8 0.5 0.6 0.3 0.5 0.8 0.8 0.6 3.3 0.8 0.5 0.6 0.4 0.5 0.7 0.6 0.5 0.2 1.5 0.7 0.8 2.8 1.2 0.5 0.8 0.4 0.1 0.2 0.2 0.3 0.2 0.2 0.0 0.2 0.2 0.2 0.2 PDE6B "CSNB3, CSNBAD2, PDEB, rd1, RP40" ENSG00000133256 "Phosphodiesterase 6B" P35913 4 625584-670782 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Congenital stationary night blindness, Disease mutation, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2;retina: 64.2" "Cell line enhanced" "Detected in some" "EFO-21: 8.0;MOLT-4: 20.5;REH: 11.1;SCLC-21H: 14.0;SH-SY5Y: 8.2;U-266/84: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054148, HPA059929" Enhanced Approved Cytosol Cytosol "HPA054148: , HPA059929: " "unprognostic (2.43e-2)" "unprognostic (1.33e-4)" "unprognostic (2.45e-4)" "unprognostic (7.18e-3)" "unprognostic (1.88e-2)" "unprognostic (5.04e-3)" "unprognostic (7.32e-3)" "prognostic favourable (5.34e-4)" "unprognostic (9.70e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.67e-2)" "unprognostic (2.26e-1)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" 1.6 1.9 12.1 4.6 19.1 6.7 3.8 2.3 13.2 2.3 1.3 30.2 1.5 0.8 2.5 3.9 1.4 9.6 3.2 5.2 18.1 10.2 4.6 0.7 4.2 12.0 29.6 9.8 2.6 1.4 9.1 3.2 2.6 14.5 2.5 1.0 64.2 3.5 2.9 0.7 1.8 2.2 2.1 20.2 8.7 2.5 3.6 22.4 4.3 11.4 0.2 8.3 4.1 1.1 16.5 14.1 11.2 5.8 10.2 13.1 7.1 0.0 0.2 0.8 0.4 0.2 0.3 0.2 0.0 0.0 0.5 1.4 0.0 0.1 0.2 8.0 0.2 0.1 1.7 0.4 0.0 0.1 0.0 0.6 0.2 0.0 4.1 0.1 0.3 0.5 0.1 2.4 0.0 0.7 0.1 0.6 0.0 0.2 20.5 0.2 6.5 0.2 11.1 0.2 0.4 1.4 0.9 14.0 8.2 0.0 0.3 0.1 0.4 0.0 0.2 0.1 0.8 0.1 0.3 5.4 15.2 0.2 0.2 0.2 0.1 11.2 4.2 0.6 11.5 5.8 10.5 10.0 7.7 7.9 6.6 16.5 12.2 13.1 1.1 10.2 5.6 14.1 11.4 7.1 12.1 19.1 2.3 10.0 18.1 10.2 29.6 9.8 14.5 22.4 PDE6C "ACHM5, COD4, PDEA2" ENSG00000095464 "Phosphodiesterase 6C" P51160 10 93612588-93666010 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 12.8" "Cell line enhanced" "Detected in some" "Hep G2: 2.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (1.39e-3)" "unprognostic (7.41e-3)" "unprognostic (2.61e-2)" "unprognostic (2.24e-1)" "unprognostic (3.17e-2)" "unprognostic (5.23e-3)" "unprognostic (2.46e-3)" "unprognostic (2.81e-3)" "unprognostic (9.68e-2)" "unprognostic (2.64e-1)" "unprognostic (1.51e-2)" "unprognostic (2.96e-3)" "unprognostic (2.19e-7)" "unprognostic (1.19e-1)" "unprognostic (6.61e-2)" "unprognostic (1.81e-1)" "unprognostic (1.80e-3)" 0.4 0.6 0.3 0.4 0.4 1.3 0.4 3.0 0.7 0.8 0.3 0.3 0.3 0.4 0.5 0.3 0.3 0.5 0.3 0.3 0.3 0.2 0.3 0.5 0.5 1.0 0.3 0.3 1.0 0.3 0.0 0.8 0.3 0.3 0.7 0.0 12.8 0.8 0.3 3.1 3.1 0.7 0.3 0.3 0.9 0.6 0.7 0.3 0.3 0.6 0.3 0.3 0.4 0.7 0.2 0.1 0.2 0.2 0.3 0.6 0.0 0.2 0.7 0.4 1.4 0.0 0.1 1.0 0.8 0.0 0.0 0.0 0.7 1.0 0.6 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.5 1.4 2.4 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 1.0 1.5 0.8 0.4 0.6 0.0 0.1 0.0 0.2 1.2 0.1 0.2 0.0 0.1 0.5 0.3 0.2 0.0 0.4 0.0 0.2 0.7 0.6 0.6 0.5 0.4 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.6 0.5 0.2 0.3 0.2 0.1 0.0 0.0 0.3 0.4 3.0 0.3 0.3 0.2 0.3 0.3 0.3 0.3 PDE6D JBTS22 ENSG00000156973 "Phosphodiesterase 6D" O43924 2 231732425-231786272 "Disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037433, HPA037434" Uncertain "HPA037433: AB_2675475, HPA037434: AB_10672490" "unprognostic (1.95e-1)" "unprognostic (2.33e-2)" "unprognostic (1.22e-1)" "unprognostic (7.72e-3)" "unprognostic (7.07e-2)" "unprognostic (5.41e-2)" "unprognostic (1.15e-1)" "unprognostic (9.48e-2)" "unprognostic (3.91e-1)" "unprognostic (1.41e-1)" "unprognostic (1.69e-1)" "unprognostic (4.75e-2)" "prognostic unfavourable (4.02e-5)" "unprognostic (1.11e-2)" "unprognostic (1.80e-2)" "unprognostic (1.46e-1)" "prognostic favourable (4.97e-4)" 9.5 16.4 24.4 11.2 23.8 9.2 11.8 20.6 22.3 11.0 11.4 21.6 8.4 9.7 11.4 11.5 9.6 10.4 10.5 12.0 22.9 21.1 13.0 11.0 10.7 15.5 23.6 16.9 9.1 11.4 14.5 16.5 17.0 20.7 9.9 13.4 18.9 10.0 14.0 6.9 9.5 9.7 16.4 25.8 12.9 10.1 27.3 18.2 20.8 10.5 2.9 17.1 11.4 8.9 24.8 27.7 34.8 29.8 15.5 39.4 19.6 10.9 8.6 16.1 12.2 19.4 16.2 6.9 11.4 19.2 17.8 25.0 3.4 10.5 8.9 10.0 9.8 8.8 9.5 12.9 23.1 26.2 11.4 13.0 5.6 5.4 9.0 8.5 7.6 11.3 11.5 17.3 13.4 18.9 3.6 10.2 11.8 21.3 27.8 26.8 12.4 11.8 19.1 7.4 13.6 18.3 8.2 15.9 14.4 9.8 8.4 19.2 7.5 18.1 8.3 11.7 3.2 25.2 9.0 25.1 10.6 21.8 12.1 16.2 18.3 34.8 24.8 32.3 24.3 23.5 19.2 24.8 24.5 24.6 24.8 24.2 17.2 24.0 21.4 15.5 29.8 27.7 39.4 19.6 24.4 23.8 20.6 19.7 22.9 21.1 23.6 16.9 20.7 18.2 PDE6G "PDEG, RP57" ENSG00000185527 "Phosphodiesterase 6G" P18545 17 81650459-81663112 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 260.3" "Cell line enhanced" "Detected in some" "Hep G2: 6.4;NB-4: 6.8;NTERA-2: 11.8;REH: 13.7" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 29.7;NK-cell: 57.8" "Group enriched" "Detected in all" 5 "granulocytes: 29.7;NK-cells: 57.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles Vesicles "HPA045118: " "unprognostic (6.16e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.51e-3)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "unprognostic (6.33e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (4.85e-2)" "unprognostic (5.01e-2)" "unprognostic (1.94e-2)" "unprognostic (5.71e-2)" "unprognostic (5.44e-2)" "unprognostic (2.73e-1)" "unprognostic (1.14e-1)" 0.9 1.3 0.4 2.9 0.5 4.7 0.7 0.5 0.6 0.4 0.8 0.5 0.4 0.0 0.4 0.5 0.6 0.3 1.6 0.5 0.5 0.7 3.8 2.6 2.0 13.8 0.6 0.5 0.5 0.4 0.0 0.5 8.6 0.5 0.5 0.5 260.3 0.5 0.4 0.6 0.8 2.8 0.4 0.8 17.9 0.7 2.2 0.5 2.5 0.6 0.4 4.6 2.1 0.4 1.3 8.6 29.7 7.7 57.8 2.4 3.7 0.2 0.3 0.5 0.0 0.3 0.0 0.0 0.3 1.2 1.2 1.3 0.1 0.8 0.6 0.2 0.7 0.1 0.2 0.2 2.9 0.2 0.0 0.9 0.1 6.4 1.0 0.1 0.2 0.0 0.2 1.2 0.0 3.3 0.1 0.3 1.3 0.8 0.1 6.8 11.8 0.4 13.7 0.1 2.1 0.0 0.0 0.1 0.3 0.0 0.3 0.5 0.1 0.8 1.3 0.4 0.1 0.2 0.3 0.1 0.6 1.0 1.6 2.7 0.2 29.7 5.1 8.6 1.2 7.7 0.4 0.8 0.3 0.6 8.6 1.3 0.7 2.4 0.7 57.8 4.2 0.8 0.0 3.7 0.4 0.5 0.5 0.6 0.5 0.7 0.6 0.5 0.5 0.5 PDE6H ENSG00000139053 "Phosphodiesterase 6H" Q13956 12 14973022-14981865 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "retina: 67.4" "Group enriched" "Detected in some" 4 "AN3-CA: 4.2;MOLT-4: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles Vesicles "HPA045118: " "unprognostic (1.47e-3)" "unprognostic (1.07e-2)" 0.1 1.3 1.2 0.2 1.5 9.4 0.1 0.1 4.2 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 1.0 2.1 0.1 0.1 0.2 0.2 2.2 0.1 0.1 0.1 0.0 0.1 2.5 0.7 0.1 0.1 67.4 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.8 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.6 0.7 0.0 0.0 1.4 0.2 0.0 0.8 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 1.2 1.5 0.1 4.2 1.0 2.1 2.2 0.1 0.7 0.1 PDE7A HCP1 ENSG00000205268 "Phosphodiesterase 7A" Q13946 8 65717510-65842322 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 87.5;skeletal muscle: 48.3" "Cell line enhanced" "Detected in many" "Karpas-707: 32.1;MOLT-4: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018770, HPA027340" Approved "CAB018770: AB_677329, HPA027340: AB_1855127" "unprognostic (2.76e-1)" "unprognostic (2.94e-2)" "unprognostic (1.36e-1)" "unprognostic (1.17e-2)" "unprognostic (2.15e-1)" "unprognostic (7.11e-2)" "prognostic unfavourable (5.64e-4)" "unprognostic (1.44e-2)" "unprognostic (6.94e-2)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.56e-1)" "prognostic unfavourable (1.35e-4)" "unprognostic (3.08e-2)" "unprognostic (1.26e-1)" "unprognostic (5.06e-2)" "unprognostic (2.03e-2)" 6.9 1.4 4.4 22.7 4.6 12.3 10.0 7.3 4.3 7.1 4.1 5.8 5.9 5.6 3.6 8.2 3.6 3.8 6.1 21.0 4.3 3.6 13.4 2.7 10.1 27.7 4.3 2.7 3.4 9.2 1.4 7.5 4.0 4.6 7.3 5.0 3.3 11.7 12.6 48.3 4.3 13.6 4.0 3.4 16.3 6.2 4.8 5.5 87.5 13.0 25.4 22.4 5.4 4.7 7.7 2.2 5.3 0.7 2.1 12.6 1.8 4.0 3.6 15.9 7.4 2.3 2.0 6.7 3.0 2.6 3.9 3.7 4.4 2.7 11.4 0.7 1.9 4.5 5.8 6.4 4.1 13.4 3.0 8.3 5.7 3.1 1.1 6.6 3.3 2.9 10.8 2.5 7.6 3.8 6.1 32.1 2.6 2.3 53.5 8.2 16.9 1.6 20.0 2.4 2.9 2.6 8.1 7.9 9.0 3.2 1.6 1.6 8.7 17.1 2.4 5.4 6.7 3.8 2.4 15.7 6.7 19.8 5.5 13.9 2.9 0.2 0.7 5.3 3.7 0.6 6.0 6.7 5.7 3.7 1.5 7.7 12.6 9.6 2.6 2.1 0.1 2.2 4.5 1.8 4.4 4.6 7.3 4.3 4.3 3.6 4.3 2.7 4.6 5.5 PDE7B ENSG00000171408 "Phosphodiesterase 7B" Q9NP56 6 135851696-136195574 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 7.1;ASC TERT1: 8.5;EFO-21: 13.1;HeLa: 7.6;HSkMC: 18.3;HUVEC TERT2: 8.5;U-2197: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 4.3" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in all" 5 "basal ganglia: 112.3" "Low region specificity" "Detected in all" HPA023967 Uncertain Approved Nucleoplasm Nucleoplasm "HPA023967: AB_1855128" "unprognostic (3.18e-1)" "unprognostic (3.47e-1)" "unprognostic (2.34e-1)" "unprognostic (1.79e-3)" "unprognostic (3.34e-1)" "unprognostic (3.22e-4)" "unprognostic (1.37e-2)" "unprognostic (3.00e-1)" "unprognostic (2.80e-1)" "unprognostic (6.73e-3)" "unprognostic (1.11e-2)" "unprognostic (7.85e-2)" "prognostic favourable (1.59e-4)" "unprognostic (3.14e-3)" "unprognostic (2.68e-2)" "unprognostic (1.43e-1)" "unprognostic (3.34e-2)" 5.8 4.3 7.3 4.0 21.9 0.8 3.6 1.6 12.8 6.2 4.0 2.3 25.2 3.6 14.2 4.9 2.8 4.2 6.1 7.9 5.1 7.4 9.6 6.4 3.3 2.8 6.4 4.2 22.7 1.6 3.7 8.7 2.2 5.9 6.8 5.0 5.4 5.0 28.5 7.2 1.5 3.7 13.5 5.3 2.3 5.2 2.9 7.1 7.7 8.3 6.1 1.9 10.6 5.1 4.3 2.6 0.6 0.9 0.7 1.8 0.3 0.0 4.4 0.1 0.0 7.1 8.5 0.0 0.4 2.3 1.7 0.9 0.0 0.0 0.0 13.1 2.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 7.6 0.0 3.1 0.1 0.0 18.3 0.0 3.4 0.0 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.0 0.5 3.1 2.9 0.1 0.1 0.0 1.5 0.0 1.8 0.0 9.1 0.0 0.1 0.0 0.0 0.5 0.0 0.7 0.2 0.9 0.6 0.2 0.2 0.1 1.5 0.4 0.2 2.6 4.3 1.8 1.0 0.3 0.7 0.1 0.2 0.2 0.3 7.3 21.9 1.6 12.8 5.1 7.4 6.4 4.2 5.9 7.1 PDE8A HsT19550 ENSG00000073417 "Phosphodiesterase 8A" O60658 15 84980440-85139145 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007722 Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA007722: AB_1855130" "unprognostic (1.68e-1)" "unprognostic (2.83e-2)" "unprognostic (4.81e-2)" "unprognostic (4.97e-2)" "unprognostic (6.25e-2)" "unprognostic (3.47e-2)" "unprognostic (2.97e-2)" "unprognostic (3.94e-2)" "unprognostic (1.03e-1)" "unprognostic (2.45e-1)" "unprognostic (8.99e-3)" "unprognostic (2.75e-2)" "unprognostic (3.42e-1)" "unprognostic (3.72e-1)" "unprognostic (4.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.94e-2)" 14.3 16.6 14.0 8.5 18.7 2.6 9.8 2.6 14.8 11.4 21.0 35.5 9.1 13.2 9.0 8.2 5.9 8.8 14.3 7.8 17.2 9.8 21.7 26.2 10.5 5.4 23.3 12.1 12.0 12.7 17.6 7.1 10.1 20.1 6.9 19.8 12.6 8.2 9.2 5.6 6.2 11.7 10.7 17.6 6.7 10.8 10.6 25.5 2.2 11.2 4.8 5.0 11.9 10.6 1.3 1.7 1.7 4.5 0.6 3.2 0.6 12.6 21.1 3.6 2.4 15.2 8.1 4.3 8.4 9.5 7.6 8.8 4.7 7.5 2.5 6.7 11.4 9.0 15.3 6.7 10.2 4.6 9.1 3.4 13.7 6.8 11.0 1.9 5.1 8.1 4.1 8.9 8.5 9.7 6.7 8.3 6.8 10.6 1.1 1.9 1.7 3.9 1.5 2.9 3.5 6.0 39.5 8.4 6.4 8.4 9.2 24.6 3.0 3.8 7.6 17.8 6.2 6.3 13.8 4.0 7.1 2.7 12.1 7.9 5.0 0.0 2.4 1.7 1.1 2.2 2.1 0.8 1.8 1.9 1.7 1.3 2.2 0.9 0.2 0.6 4.5 0.0 3.2 0.6 14.0 18.7 2.6 14.8 17.2 9.8 23.3 12.1 20.1 25.5 PDE8B ENSG00000113231 "Phosphodiesterase 8B" O95263 5 77210449-77429807 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "Cushing syndrome, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "thyroid gland: 67.7" "Group enriched" "Detected in some" 4 "BJ hTERT+: 12.1;HeLa: 27.8;SK-BR-3: 7.4" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 35.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "HPA036911, HPA036912" Supported Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA036911: , HPA036912: AB_10670377" "unprognostic (1.30e-1)" "unprognostic (7.95e-2)" "unprognostic (3.35e-2)" "unprognostic (7.61e-4)" "unprognostic (1.59e-2)" "unprognostic (1.41e-1)" "unprognostic (2.66e-2)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.26e-2)" "unprognostic (3.98e-2)" "unprognostic (2.44e-1)" "unprognostic (9.04e-3)" "unprognostic (3.40e-2)" "unprognostic (3.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.19e-2)" 6.8 2.5 9.9 0.7 14.2 0.4 3.8 1.1 16.3 6.3 1.2 2.3 0.3 1.2 11.3 3.2 1.1 10.1 2.1 7.9 8.2 9.2 3.1 1.2 2.2 0.7 5.4 8.3 1.9 4.2 0.3 3.8 13.1 8.6 10.5 0.8 2.0 5.3 7.1 0.4 0.7 1.3 10.3 2.3 0.4 1.5 1.5 5.7 0.3 67.7 0.3 0.7 0.8 1.4 0.2 0.8 1.4 2.3 0.4 0.4 0.1 0.3 3.3 1.3 0.3 1.2 0.0 0.5 1.1 12.1 0.2 0.1 1.3 0.2 0.5 0.2 0.1 0.9 0.1 0.0 0.2 0.2 1.0 0.7 27.8 0.3 0.0 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.6 0.7 0.8 0.1 0.8 1.4 0.7 0.0 0.3 3.7 1.0 1.6 7.4 0.8 1.6 1.1 0.6 0.4 0.2 0.2 0.6 0.9 0.5 0.6 1.6 0.7 0.4 0.0 0.3 1.4 0.3 2.2 0.1 0.2 0.2 0.3 0.8 0.2 0.4 0.0 0.3 0.4 2.3 0.5 0.1 0.1 9.9 14.2 1.1 16.3 8.2 9.2 5.4 8.3 8.6 5.7 PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653636-42775509 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 16.1;EFO-21: 16.2;MCF7: 12.0;NB-4: 17.9;NTERA-2: 22.1;SCLC-21H: 12.3" "Cancer enhanced" "Detected in all" "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 6.8" "Group enriched" "Detected in many" 4 "NK-cells: 1.7;T-cells: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011380 Enhanced Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA011380: AB_1855132" "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" 6.1 6.6 9.9 6.8 15.2 0.8 9.4 13.7 9.0 3.7 37.1 11.9 14.0 3.0 5.7 18.8 6.1 10.3 7.7 3.5 6.2 7.7 13.2 2.5 4.7 4.6 10.0 4.9 4.1 4.0 4.7 6.0 9.6 6.9 33.2 15.8 9.7 8.8 15.9 2.3 3.8 26.1 22.3 8.0 15.9 8.4 1.5 8.9 4.9 5.2 2.1 4.1 12.6 4.0 0.5 0.9 1.0 0.1 1.7 6.8 0.5 0.0 1.5 16.1 1.9 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.7 9.7 0.0 16.2 0.0 0.0 1.4 5.2 0.0 0.0 5.5 0.0 0.0 3.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 12.0 0.8 17.9 22.1 0.0 0.0 0.0 0.6 11.0 4.4 12.3 7.3 2.7 0.0 0.2 0.1 9.9 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.1 0.6 0.2 0.5 6.8 1.7 1.0 1.7 0.1 0.9 2.2 0.5 9.9 15.2 13.7 6.7 6.2 7.7 10.0 4.9 6.9 8.9 PNP "NP, PUNP" ENSG00000198805 "Purine nucleoside phosphorylase" P00491 14 20468954-20477094 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 153.1" "Cell line enhanced" "Detected in many" "HL-60: 81.4;U-937: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001625 Enhanced Supported Cytosol 100000000 Cytosol "HPA001625: AB_1854577" "unprognostic (1.20e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" "unprognostic (1.70e-1)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "prognostic unfavourable (4.43e-4)" "unprognostic (4.94e-3)" "unprognostic (3.87e-2)" "unprognostic (7.45e-2)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "prognostic favourable (2.24e-4)" "unprognostic (1.69e-1)" "unprognostic (7.54e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" 24.7 7.6 9.5 15.0 14.0 69.4 15.7 13.9 11.8 9.5 19.1 6.2 25.2 29.4 5.9 153.1 34.0 7.8 15.7 12.1 11.5 8.4 49.7 24.2 18.3 13.2 13.5 3.4 3.6 11.0 8.7 8.4 45.3 17.7 6.0 16.1 3.8 9.2 7.9 3.3 10.6 32.0 9.8 16.3 18.0 17.0 4.5 12.5 7.0 7.1 21.7 19.1 7.5 14.7 13.1 20.7 4.1 12.4 15.7 33.7 12.1 13.2 17.9 3.8 8.6 4.3 3.5 11.7 13.6 6.4 11.1 11.0 10.3 12.2 35.4 15.8 7.2 14.3 20.1 25.6 14.8 11.4 17.7 29.6 15.3 17.0 4.0 81.4 15.4 2.3 9.3 33.5 14.8 47.3 14.5 22.1 13.9 12.3 23.9 48.0 10.8 29.9 20.2 5.7 13.7 39.4 12.6 16.6 3.7 26.0 33.2 2.1 12.2 14.5 37.9 7.6 10.1 17.1 23.0 10.2 17.0 40.1 6.5 92.8 0.7 4.0 12.4 4.1 18.1 11.5 33.7 11.2 20.3 20.0 20.7 13.1 12.9 16.3 1.6 15.7 10.6 11.7 6.9 12.1 9.5 14.0 13.9 11.8 11.5 8.4 13.5 3.4 17.7 12.5 POLA1 "NSX, p180, POLA" ENSG00000101868 "DNA polymerase alpha 1, catalytic subunit" P09884 X 24693919-24996986 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA replication, Host-virus interaction" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002947, CAB012274" Supported Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB012274: , HPA002947: AB_1079652" "unprognostic (6.92e-2)" "unprognostic (4.43e-3)" "unprognostic (3.27e-3)" "unprognostic (1.53e-2)" "unprognostic (2.53e-1)" "unprognostic (1.49e-1)" "prognostic unfavourable (4.80e-5)" "unprognostic (1.87e-1)" "unprognostic (9.25e-3)" "unprognostic (2.48e-2)" "unprognostic (8.41e-2)" "unprognostic (7.42e-2)" "unprognostic (2.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-2)" "unprognostic (3.08e-1)" 10.5 5.5 8.0 15.0 10.2 14.3 10.9 12.0 9.6 10.1 9.7 11.8 5.8 5.7 11.2 7.7 10.2 8.9 5.5 9.3 7.8 6.6 6.1 4.9 7.2 12.7 10.3 4.5 12.9 7.3 8.5 8.5 10.7 8.7 7.3 11.0 7.5 7.9 9.3 22.4 9.3 7.5 9.7 13.1 9.0 7.9 5.7 10.0 30.1 7.0 8.5 14.7 9.9 10.6 4.6 2.5 1.2 4.6 2.7 3.8 1.7 14.0 10.5 13.9 11.2 2.6 3.1 3.1 10.5 5.8 11.3 13.0 8.7 7.4 18.0 3.6 4.5 11.6 26.4 8.5 15.3 9.3 11.2 13.4 20.5 6.5 1.1 17.5 7.2 2.0 1.8 14.1 4.1 5.8 12.3 9.2 7.8 9.8 19.0 5.9 13.5 8.8 17.1 36.5 13.6 4.1 9.3 12.6 7.8 12.4 5.9 5.6 11.6 5.8 4.6 10.0 6.9 19.1 10.0 5.5 7.9 14.5 5.8 8.3 11.1 0.0 2.0 1.2 3.0 4.6 2.9 4.6 3.4 3.8 2.5 3.2 2.4 2.4 0.6 2.7 1.3 1.6 3.6 1.7 8.0 10.2 12.0 9.6 7.8 6.6 10.3 4.5 8.7 10.0 POLA2 FLJ21662 ENSG00000014138 "DNA polymerase alpha 2, accessory subunit" Q14181 11 65261762-65305589 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037570 Supported Supported Nucleoplasm Nucleoplasm "HPA037570: AB_10672280" "unprognostic (2.28e-1)" "prognostic favourable (4.61e-4)" "unprognostic (1.67e-2)" "unprognostic (7.44e-2)" "unprognostic (5.20e-2)" "unprognostic (3.18e-2)" "prognostic unfavourable (2.11e-6)" "unprognostic (1.14e-1)" "unprognostic (2.87e-2)" "unprognostic (1.15e-2)" "unprognostic (4.05e-2)" "unprognostic (1.83e-1)" "prognostic unfavourable (4.09e-8)" "unprognostic (1.60e-3)" "unprognostic (8.26e-2)" "unprognostic (8.16e-2)" "unprognostic (6.25e-3)" 7.5 6.6 4.9 11.9 8.8 9.8 7.5 14.1 8.8 12.0 9.6 9.8 6.4 6.7 10.1 5.5 10.4 9.3 5.9 6.1 5.2 4.5 7.9 7.0 7.5 14.7 10.3 5.5 10.3 7.9 8.0 4.8 9.3 6.5 7.1 9.6 6.7 8.9 7.5 6.5 8.0 9.2 10.7 10.2 13.6 8.8 15.0 8.4 35.7 7.9 10.3 19.7 8.6 7.3 6.0 13.3 8.0 10.1 4.9 7.3 7.7 14.2 13.1 21.6 10.0 3.2 3.9 7.4 9.7 15.5 31.4 23.2 5.2 12.5 17.1 11.2 8.5 8.9 17.6 14.6 26.9 9.2 6.6 12.8 19.8 5.9 1.9 11.9 10.6 2.6 2.0 27.2 5.7 11.6 12.4 11.5 21.2 19.6 25.5 5.3 16.1 8.3 13.8 12.6 16.4 9.4 9.8 14.1 8.4 9.3 10.2 3.2 12.8 6.1 4.3 11.6 9.4 15.3 7.0 5.4 6.4 17.6 8.3 7.6 15.5 8.0 10.1 3.9 6.5 9.5 7.3 6.0 6.9 7.1 13.3 5.6 5.6 5.1 5.0 4.9 7.6 10.4 7.1 7.7 4.9 8.8 14.1 8.8 5.2 4.5 10.3 5.5 6.5 8.4 POLB ENSG00000070501 "DNA polymerase beta" P06746 8 42338454-42371808 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.6" "Cell line enhanced" "Detected in all" "HMC-1: 79.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 73.6" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011616, HPA049104" Enhanced Uncertain Vesicles Vesicles "CAB011616: AB_731977, HPA049104: " "unprognostic (1.67e-1)" "unprognostic (2.68e-3)" "unprognostic (2.43e-1)" "prognostic unfavourable (1.46e-4)" "unprognostic (8.49e-2)" "unprognostic (2.64e-2)" "unprognostic (4.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.31e-2)" "unprognostic (1.99e-1)" "unprognostic (4.57e-2)" "unprognostic (4.77e-1)" "prognostic unfavourable (2.15e-5)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (4.22e-2)" "prognostic favourable (5.65e-4)" 5.5 8.6 10.1 9.5 10.7 21.9 13.5 73.6 16.6 7.0 5.5 5.8 6.0 4.9 6.2 11.2 12.4 6.3 11.3 16.3 9.8 9.6 7.2 15.8 9.1 11.8 8.4 10.3 10.3 7.7 10.3 11.6 5.0 10.9 11.4 6.3 6.8 22.1 6.9 36.6 10.8 4.9 6.6 10.0 8.1 6.4 29.5 5.4 9.7 7.7 17.2 10.1 11.5 9.2 4.9 33.8 25.1 9.4 7.9 7.2 4.2 10.8 6.5 11.3 22.5 6.3 6.0 9.5 6.9 8.0 11.5 10.6 9.1 12.7 9.8 8.8 4.4 5.5 9.4 8.1 14.2 6.4 10.2 7.1 5.4 12.3 9.7 5.0 79.7 5.3 9.6 8.5 10.0 8.7 15.5 6.3 11.1 6.4 20.7 14.2 15.2 7.5 11.9 11.4 8.4 21.6 8.8 6.4 11.7 8.2 5.5 20.9 14.7 8.6 4.8 5.5 7.7 13.7 6.7 9.2 15.3 13.9 5.5 10.7 14.3 12.5 5.9 17.3 4.9 7.2 5.5 4.9 5.2 5.3 6.1 4.5 5.8 5.4 25.1 7.9 9.4 33.8 7.2 4.2 10.1 10.7 73.6 16.6 9.8 9.6 8.4 10.3 10.9 5.4 POLD1 "CDC2, POLD" ENSG00000062822 "DNA polymerase delta 1, catalytic subunit" P28340 19 50384204-50418016 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004375, HPA046524" Supported Supported Nucleoplasm Nucleoplasm "CAB004375: AB_675487, HPA046524: " "unprognostic (2.45e-1)" "unprognostic (7.02e-3)" "unprognostic (1.59e-1)" "unprognostic (4.35e-2)" "unprognostic (2.55e-1)" "unprognostic (1.85e-2)" "prognostic unfavourable (2.87e-6)" "unprognostic (4.12e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-1)" "unprognostic (5.08e-1)" "unprognostic (3.92e-3)" "unprognostic (4.01e-3)" "unprognostic (1.28e-2)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "unprognostic (3.70e-2)" 7.9 5.7 5.4 18.3 9.9 31.6 6.6 9.4 5.4 8.2 10.0 6.1 5.9 6.8 9.5 7.2 11.3 6.9 5.2 5.5 4.4 3.2 7.6 9.3 10.9 15.7 7.0 3.6 8.2 8.4 5.2 5.1 10.9 6.7 6.3 5.2 4.9 8.1 5.4 7.2 13.1 9.9 6.2 7.7 14.1 6.5 13.2 6.5 27.4 12.1 8.1 14.2 5.9 7.8 9.3 10.5 2.1 8.5 5.4 7.3 5.6 18.1 25.0 13.7 7.9 1.7 1.5 14.1 11.3 5.0 13.9 17.8 13.6 14.4 26.0 6.4 3.4 14.9 16.2 12.3 4.8 21.9 43.5 22.6 24.2 17.9 1.6 21.5 20.0 2.9 3.8 12.6 3.8 7.1 24.3 20.2 5.8 12.2 33.3 33.7 16.1 18.2 33.1 23.0 22.8 4.4 17.3 14.3 12.9 11.2 13.8 2.6 7.6 20.4 5.6 7.1 23.0 7.6 19.8 19.1 31.4 27.8 7.7 24.3 6.9 1.6 6.2 2.1 7.3 7.8 6.2 7.8 6.5 5.9 5.7 9.3 6.5 5.9 1.1 5.4 8.5 10.5 4.5 5.6 5.4 9.9 9.4 5.4 4.4 3.2 7.0 3.6 6.7 6.5 POLD2 ENSG00000106628 "DNA polymerase delta 2, accessory subunit" P49005 7 44114681-44124358 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026745 Approved Enhanced Nucleoplasm Nucleoplasm "HPA026745: AB_1855520" "unprognostic (9.09e-2)" "unprognostic (1.41e-1)" "unprognostic (9.89e-2)" "unprognostic (1.84e-3)" "unprognostic (1.55e-1)" "unprognostic (2.10e-3)" "unprognostic (1.50e-3)" "unprognostic (4.94e-3)" "unprognostic (8.17e-2)" "unprognostic (1.01e-3)" "unprognostic (4.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.72e-2)" "unprognostic (2.14e-1)" "unprognostic (5.18e-2)" "unprognostic (1.03e-1)" "unprognostic (4.44e-3)" 17.2 19.1 17.5 14.3 16.7 16.3 33.9 14.3 25.9 15.8 15.4 17.1 12.6 13.9 16.1 9.7 27.5 34.5 14.5 35.9 16.3 13.8 15.9 43.6 15.3 16.2 15.2 14.7 24.4 49.0 18.9 17.9 12.9 15.0 15.9 12.9 17.4 19.9 14.3 42.6 19.3 11.5 15.7 13.7 11.9 16.0 14.4 14.8 27.7 20.3 25.1 15.8 13.4 16.7 28.1 37.0 3.2 13.7 13.3 29.3 21.3 26.1 34.6 19.3 40.4 17.2 18.5 19.2 16.2 16.3 22.2 16.6 29.2 25.2 60.6 20.7 23.2 36.3 31.6 44.1 14.5 17.2 37.1 13.4 37.2 24.6 19.6 40.7 16.4 16.8 27.0 34.3 33.5 18.6 48.8 29.1 24.5 42.7 49.6 77.1 30.3 34.0 33.5 25.9 86.0 19.3 16.9 38.3 30.0 20.1 72.7 13.8 42.0 52.6 14.5 29.5 37.2 36.1 50.5 45.9 67.8 58.1 26.4 41.3 41.6 0.5 13.7 3.2 17.9 12.4 26.8 28.1 21.6 18.2 23.2 27.3 29.3 21.4 1.1 13.3 11.8 37.0 17.0 21.3 17.5 16.7 14.3 25.9 16.3 13.8 15.2 14.7 15.0 14.8 POLD3 "KIAA0039, P66, P68, PPP1R128" ENSG00000077514 "DNA polymerase delta 3, accessory subunit" Q15054 11 74493851-74669117 "Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058846 Enhanced Supported Nucleoplasm Nucleoplasm "HPA058846: " "unprognostic (3.68e-1)" "unprognostic (3.22e-2)" "unprognostic (2.05e-3)" "unprognostic (3.28e-1)" "unprognostic (1.74e-1)" "unprognostic (3.49e-1)" "prognostic unfavourable (9.17e-4)" "unprognostic (1.08e-1)" "prognostic unfavourable (5.48e-4)" "unprognostic (3.99e-3)" "unprognostic (1.54e-3)" "unprognostic (9.21e-3)" "prognostic unfavourable (7.90e-6)" "unprognostic (7.92e-3)" "unprognostic (2.65e-1)" "unprognostic (9.11e-2)" "unprognostic (1.23e-1)" 12.6 8.2 11.3 12.8 17.5 8.3 12.7 10.3 16.4 13.8 15.6 12.5 10.3 14.5 18.1 11.7 14.1 15.6 14.1 9.6 10.2 7.8 40.3 10.0 12.7 14.0 12.1 13.1 15.9 17.5 9.3 16.0 12.4 12.3 13.2 17.2 9.9 13.0 11.8 10.4 10.8 17.1 18.2 9.1 13.9 14.5 19.8 13.9 15.2 14.2 8.0 13.5 15.9 13.7 8.1 14.7 16.5 19.0 8.7 11.0 9.6 12.3 11.2 17.4 11.9 5.4 9.3 12.4 16.8 9.4 17.6 14.9 14.7 16.1 17.6 12.5 8.0 16.2 14.4 11.0 22.2 13.2 9.2 11.2 17.5 4.9 3.9 21.4 10.2 4.1 7.0 20.4 11.0 6.7 10.1 14.2 10.1 9.7 24.0 9.6 10.5 11.6 23.1 43.9 14.6 8.0 11.9 11.7 7.8 19.9 10.0 19.4 11.7 13.7 6.4 17.4 12.6 19.5 13.2 10.0 20.9 39.4 10.0 13.6 13.1 6.0 19.0 12.5 8.2 15.1 8.1 8.1 10.4 7.2 14.7 6.7 10.4 8.5 16.5 8.7 14.8 4.3 11.0 9.6 11.3 17.5 10.3 16.4 10.2 7.8 12.1 13.1 12.3 13.9 POLD4 "p12, POLDS" ENSG00000175482 "DNA polymerase delta 4, accessory subunit" Q9HCU8 11 67350777-67356972 "Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA078008 Approved "Centriolar satellite" "Centriolar satellite" "HPA078008: " "unprognostic (7.55e-3)" "unprognostic (2.71e-1)" "unprognostic (3.93e-2)" "unprognostic (2.75e-1)" "unprognostic (1.19e-2)" "unprognostic (1.03e-1)" "unprognostic (8.25e-2)" "unprognostic (1.43e-2)" "unprognostic (4.82e-1)" "unprognostic (2.02e-1)" "unprognostic (3.19e-2)" "unprognostic (2.53e-1)" "unprognostic (2.39e-3)" "unprognostic (1.70e-1)" "unprognostic (4.11e-2)" "unprognostic (1.95e-1)" "unprognostic (9.36e-2)" 19.0 19.7 6.5 47.0 9.3 19.6 15.0 3.3 8.9 14.9 35.1 11.4 13.6 47.2 13.2 15.6 32.4 10.3 26.9 24.0 6.1 6.1 34.3 90.7 21.3 42.9 10.8 5.2 13.0 26.8 2.7 9.8 23.7 9.1 20.2 9.9 10.0 27.2 13.4 25.7 12.7 56.9 16.5 10.5 30.1 36.2 10.9 8.3 20.6 18.5 19.4 48.9 25.4 17.2 69.6 28.3 49.0 65.8 9.8 24.8 24.3 13.3 36.7 1.0 4.0 5.2 14.2 2.2 15.8 7.5 2.9 3.0 6.1 43.5 35.4 49.4 7.0 17.2 0.2 15.4 0.2 14.4 1.8 8.9 9.0 7.2 15.1 2.9 39.6 13.0 10.3 7.3 8.0 11.4 7.7 11.8 5.9 22.2 3.5 6.9 2.7 23.4 6.5 8.1 9.5 7.2 9.1 0.3 3.8 8.4 6.2 26.6 17.2 10.5 24.1 9.7 6.3 23.0 5.3 15.8 4.5 18.5 28.7 6.9 10.5 22.3 30.1 49.0 15.4 35.7 14.1 59.2 17.2 15.3 28.3 69.6 19.5 16.8 29.0 9.8 65.8 22.6 24.8 24.3 6.5 9.3 3.3 8.9 6.1 6.1 10.8 5.2 9.1 8.3 POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687365 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 34.8" "Cell type enhanced" "Detected in some" "NK-cell: 4.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA058210, HPA067385" Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA058210: , HPA067385: " "unprognostic (1.60e-1)" "unprognostic (1.77e-3)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-2)" "unprognostic (3.96e-3)" "unprognostic (2.23e-1)" "prognostic unfavourable (1.44e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "prognostic unfavourable (3.19e-8)" "unprognostic (8.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" 6.1 3.4 6.7 10.2 4.4 29.3 6.2 34.8 14.4 7.0 6.6 2.0 7.6 7.3 6.1 4.4 7.5 6.2 6.5 4.7 5.6 1.6 3.8 8.6 5.4 8.2 3.3 4.3 8.7 6.8 3.6 3.1 6.5 5.1 6.8 7.7 4.3 8.7 7.4 8.9 17.9 8.5 6.8 3.7 16.7 7.8 25.6 4.4 29.8 5.1 6.0 10.3 6.7 8.7 0.5 1.7 0.8 0.8 4.8 0.7 0.5 11.1 14.9 22.1 10.6 4.7 3.6 19.7 11.4 5.2 13.7 10.0 18.0 6.6 12.8 4.8 6.2 15.5 15.4 7.7 8.4 5.9 19.5 20.2 19.2 8.8 0.9 15.8 11.6 2.8 3.0 14.2 4.7 4.8 22.6 7.2 6.7 18.1 25.9 28.9 17.2 8.9 21.5 12.5 5.8 4.3 18.3 18.5 10.6 13.3 10.9 2.5 16.1 9.8 4.3 12.5 12.8 9.4 11.5 9.6 6.5 20.1 6.8 21.9 8.8 0.0 0.3 0.8 0.5 0.1 0.7 0.5 0.3 0.4 0.7 0.3 0.5 0.3 0.1 4.8 0.8 1.7 0.6 0.5 6.7 4.4 34.8 14.4 5.6 1.6 3.3 4.3 5.1 4.4 POLE2 DPE2 ENSG00000100479 "DNA polymerase epsilon 2, accessory subunit" P56282 14 49643555-49688422 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA replication" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.6;lymphoid tissue: 17.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027555 Uncertain Supported "Nucleoplasm,Nuclear bodies,Vesicles" "Nucleoplasm, Nuclear bodies" Vesicles "HPA027555: AB_10610282" "unprognostic (1.42e-1)" "unprognostic (6.57e-3)" "unprognostic (3.53e-2)" "unprognostic (7.44e-2)" "unprognostic (2.04e-2)" "unprognostic (4.99e-3)" "unprognostic (7.60e-3)" "unprognostic (2.32e-3)" "unprognostic (1.10e-3)" "unprognostic (2.69e-2)" "unprognostic (1.88e-2)" "unprognostic (1.37e-3)" "unprognostic (5.13e-11)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.50e-3)" 3.3 2.2 1.5 11.6 2.8 17.6 3.4 1.7 1.6 4.4 4.2 1.1 1.5 2.6 2.8 3.5 9.0 2.4 2.3 1.6 1.0 1.2 2.5 5.1 2.2 5.3 1.1 0.3 2.7 5.0 1.4 2.5 4.1 1.4 2.1 5.2 2.6 2.6 0.7 1.1 3.7 7.7 2.9 2.7 5.4 3.0 5.3 2.4 17.6 1.6 10.3 8.4 2.1 4.2 1.2 0.9 0.7 0.0 3.2 2.7 0.5 17.1 8.8 16.7 7.7 0.8 4.9 8.5 9.8 5.0 15.6 18.1 8.8 13.5 10.7 5.6 5.5 10.6 16.7 6.0 18.5 12.5 9.2 15.9 9.7 10.9 0.4 18.9 6.9 1.4 0.4 8.5 1.4 9.0 13.9 6.9 15.6 15.0 19.2 12.4 9.8 20.6 16.4 15.4 9.7 5.6 9.7 12.0 6.9 9.9 5.8 3.1 11.7 6.7 3.2 2.5 18.6 10.4 7.7 5.0 10.2 24.7 4.7 14.0 10.0 0.0 0.0 0.7 0.9 0.0 0.7 1.2 0.9 1.7 0.6 1.2 0.1 0.8 0.0 3.2 0.0 0.9 2.7 0.5 1.5 2.8 1.7 1.6 1.0 1.2 1.1 0.3 1.4 2.4 POLE3 "CHARAC17, CHRAC17, p17, Ybl1" ENSG00000148229 "DNA polymerase epsilon 3, accessory subunit" Q9NRF9 9 113407235-113410672 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047945 Uncertain Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA047945: " "unprognostic (9.55e-2)" "unprognostic (3.39e-3)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.86e-2)" "prognostic unfavourable (8.35e-4)" "unprognostic (1.04e-2)" "unprognostic (1.60e-2)" "unprognostic (1.10e-1)" "unprognostic (4.59e-3)" "unprognostic (2.31e-3)" "unprognostic (1.75e-2)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" 16.9 23.9 18.2 22.0 18.5 56.3 19.3 36.0 25.0 17.0 17.6 15.8 12.5 15.1 18.2 16.5 27.8 17.6 17.0 17.9 16.1 14.8 14.3 29.5 15.8 29.0 15.1 18.5 15.4 20.8 13.1 8.4 21.2 20.0 15.9 20.3 12.4 17.9 16.3 48.3 24.7 17.3 16.9 16.9 26.8 17.2 29.9 15.9 35.0 16.3 27.3 32.4 18.8 16.7 34.9 33.5 34.3 34.4 28.0 44.0 47.7 15.7 19.7 13.9 20.8 7.9 7.1 12.2 21.1 10.8 23.9 18.9 18.2 14.4 57.4 13.1 12.3 27.1 27.0 23.2 22.1 10.9 16.3 29.8 20.4 18.6 8.5 61.7 18.0 8.1 16.0 20.7 26.8 16.5 41.5 32.1 16.6 40.1 42.3 33.2 17.9 35.7 43.4 57.9 32.2 10.4 15.1 30.1 17.4 30.6 19.4 16.5 29.0 27.8 13.6 17.8 24.1 22.4 36.0 16.8 54.9 77.4 16.2 36.5 21.2 25.4 34.0 34.3 35.5 34.4 44.0 34.9 34.0 33.7 33.2 33.5 36.9 34.3 7.2 28.0 26.6 33.5 39.0 47.7 18.2 18.5 36.0 25.0 16.1 14.8 15.1 18.5 20.0 15.9 POLE4 p12 ENSG00000115350 "DNA polymerase epsilon 4, accessory subunit" Q9NR33 2 74958492-74970128 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054979, HPA071815" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA054979: , HPA071815: " "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.19e-2)" "unprognostic (4.85e-2)" "unprognostic (1.59e-2)" "prognostic unfavourable (6.49e-4)" "unprognostic (3.09e-1)" "unprognostic (1.99e-1)" "unprognostic (2.95e-1)" "unprognostic (1.39e-2)" "unprognostic (4.44e-2)" "unprognostic (8.64e-3)" "unprognostic (6.61e-2)" "unprognostic (3.73e-1)" "unprognostic (3.47e-2)" "unprognostic (1.95e-1)" 19.2 14.5 23.6 15.2 17.3 27.1 21.4 4.4 15.5 18.4 13.4 8.6 7.0 9.0 10.4 9.0 10.0 9.7 13.1 18.1 15.9 10.6 11.6 18.8 10.7 17.0 13.9 12.6 12.8 12.5 2.8 3.9 9.6 12.2 12.0 8.8 13.9 16.2 11.2 28.1 8.1 12.4 14.1 11.7 12.2 12.5 11.0 10.0 5.5 13.1 15.1 10.4 13.9 31.9 14.7 14.7 8.0 22.2 4.4 9.9 12.3 11.7 11.2 1.0 1.0 3.8 8.6 0.0 8.0 9.9 12.8 10.9 14.9 5.2 11.5 6.7 9.0 5.3 5.3 6.6 15.0 5.2 14.4 8.9 6.5 14.7 13.9 12.6 14.1 8.7 13.0 5.3 11.8 5.5 10.9 6.8 9.7 11.4 3.7 35.6 7.8 21.1 4.5 9.6 9.3 10.6 0.3 3.5 5.3 11.0 4.6 6.3 3.4 4.1 6.2 2.9 3.3 2.0 7.6 2.4 1.6 4.2 10.5 18.9 14.1 2.3 22.2 8.0 6.3 13.2 7.0 14.7 8.9 7.8 12.9 13.7 9.9 6.9 1.6 4.4 12.4 14.7 8.5 12.3 23.6 17.3 4.4 15.5 15.9 10.6 13.9 12.6 12.2 10.0 POLG "POLG1, POLGA" ENSG00000140521 "DNA polymerase gamma, catalytic subunit" P54098 15 89305198-89334861 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease mutation, Epilepsy, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056821, HPA078482" Approved Supported Mitochondria Mitochondria "HPA056821: , HPA078482: " "unprognostic (1.87e-1)" "unprognostic (4.71e-2)" "unprognostic (2.61e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (3.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.63e-1)" "unprognostic (1.41e-1)" "prognostic unfavourable (5.73e-4)" "unprognostic (2.65e-3)" "unprognostic (1.58e-2)" "unprognostic (4.29e-2)" "unprognostic (2.07e-1)" "unprognostic (3.45e-1)" 17.8 15.2 19.8 19.0 19.2 16.8 24.6 23.2 20.9 14.1 16.0 14.6 13.6 20.0 17.6 9.0 20.7 14.3 14.0 17.4 16.7 8.8 14.9 19.5 17.8 21.8 17.3 15.3 16.6 17.9 17.7 12.9 16.2 16.0 15.4 13.2 10.5 15.9 12.0 35.9 19.8 18.5 14.1 12.7 22.9 16.2 12.4 17.3 29.0 15.4 12.1 19.2 16.5 18.9 6.0 9.0 9.0 6.5 9.2 10.9 6.7 6.8 13.0 9.0 11.7 14.7 9.4 11.5 13.7 7.3 14.1 11.1 19.0 17.2 10.8 21.2 10.8 14.9 24.0 11.6 4.7 23.3 20.6 16.4 13.7 6.8 12.5 15.2 27.1 8.5 17.0 9.7 8.3 16.8 14.4 12.2 11.4 12.1 17.3 15.5 8.1 5.8 17.7 11.0 15.3 8.0 16.8 20.0 7.3 19.5 14.3 15.9 11.9 17.1 12.5 19.1 13.2 28.0 13.1 13.1 7.6 15.0 12.2 17.5 15.2 4.9 6.3 9.0 9.2 6.5 8.0 3.3 7.6 10.9 9.0 6.0 6.6 6.9 2.3 9.2 5.2 6.0 4.3 6.7 19.8 19.2 23.2 20.9 16.7 8.8 17.3 15.3 16.0 17.3 POLG2 "HP55, MTPOLB" ENSG00000256525 "DNA polymerase gamma 2, accessory subunit" Q9UHN1 17 64477785-64497036 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease mutation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017030, HPA023202" Approved Approved "Nuclear bodies,Mitochondria" "Nuclear bodies" Mitochondria "CAB017030: , HPA023202: AB_1855523" "unprognostic (1.76e-1)" "unprognostic (2.20e-1)" "unprognostic (1.59e-1)" "unprognostic (7.02e-2)" "unprognostic (6.01e-2)" "unprognostic (2.91e-2)" "prognostic unfavourable (1.39e-6)" "unprognostic (4.38e-2)" "unprognostic (8.46e-2)" "unprognostic (3.14e-1)" "unprognostic (5.17e-3)" "prognostic unfavourable (6.59e-4)" "prognostic unfavourable (1.17e-5)" "unprognostic (5.17e-2)" "unprognostic (1.58e-1)" "unprognostic (2.88e-2)" "unprognostic (4.82e-2)" 6.7 9.3 5.4 17.5 10.0 8.1 8.2 10.9 8.7 7.7 7.8 7.0 11.1 7.9 10.2 6.8 6.4 7.5 7.9 7.3 5.6 4.4 7.8 7.8 10.4 12.2 10.8 5.2 13.0 9.4 5.0 9.9 6.9 8.7 8.0 5.7 5.8 8.6 11.9 10.7 10.5 8.4 9.3 5.6 11.5 6.9 24.2 7.9 9.8 9.6 5.4 13.3 6.6 11.5 12.2 10.5 6.5 8.2 6.0 12.2 4.4 6.7 8.3 6.0 7.4 5.7 4.6 7.3 4.0 3.8 6.1 5.3 8.6 5.4 12.4 4.9 2.1 5.6 8.2 3.8 7.7 3.5 9.4 8.4 10.0 8.5 6.4 11.9 9.4 4.6 4.4 4.9 7.3 4.4 14.7 4.8 5.9 9.0 12.6 15.7 6.3 9.3 11.8 19.6 13.1 5.6 2.0 8.4 9.4 3.2 7.3 7.4 7.1 10.0 4.9 6.6 8.9 5.7 10.4 8.5 5.7 9.4 5.2 11.1 4.6 6.5 5.9 6.5 7.9 3.5 7.5 12.2 8.8 7.6 10.5 12.1 12.2 11.6 1.2 6.0 8.2 4.8 8.4 4.4 5.4 10.0 10.9 8.7 5.6 4.4 10.8 5.2 8.7 7.9 POLH "RAD30A, XP-V" ENSG00000170734 "DNA polymerase eta" Q9Y253 6 43576150-43615660 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Disease mutation, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006721, HPA026762" Approved Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006721: AB_1847785, HPA026762: AB_10601248" "unprognostic (1.79e-1)" "unprognostic (7.29e-2)" "unprognostic (2.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.61e-1)" "unprognostic (5.11e-3)" "unprognostic (9.68e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (7.75e-2)" "unprognostic (4.11e-3)" "unprognostic (2.24e-1)" "unprognostic (9.50e-2)" "unprognostic (6.73e-2)" "unprognostic (8.77e-2)" "unprognostic (7.91e-2)" "unprognostic (6.02e-2)" 7.4 9.4 7.5 9.7 10.4 4.6 7.2 10.5 10.5 8.5 8.4 12.7 8.0 5.7 9.6 7.1 11.4 7.8 6.2 6.7 5.3 4.4 7.2 7.5 9.8 16.3 8.9 8.1 7.4 13.0 7.1 9.7 5.1 7.9 6.9 10.1 8.9 8.6 5.6 9.5 11.7 7.9 11.8 6.9 9.2 7.6 24.7 6.8 22.1 9.9 6.2 18.3 8.6 8.4 8.6 4.3 4.5 2.6 6.8 7.2 3.2 20.2 4.7 6.3 9.2 9.0 14.9 15.0 21.7 6.8 12.7 14.7 5.3 3.6 22.5 5.5 8.8 5.1 6.4 13.7 15.8 11.3 4.9 6.6 13.1 15.4 6.7 11.2 8.9 10.0 16.7 10.4 5.6 12.0 10.4 13.5 16.0 6.7 10.2 2.9 1.9 3.5 11.2 6.5 5.6 4.8 15.2 7.1 2.4 6.9 5.8 3.4 8.2 5.0 16.2 11.8 11.4 5.5 10.9 12.7 8.8 40.6 5.6 6.6 12.8 4.5 2.6 4.1 7.2 2.5 6.4 7.8 6.0 5.2 2.1 8.6 5.0 5.2 2.0 6.8 1.9 4.3 7.0 3.2 7.5 10.4 10.5 10.5 5.3 4.4 8.9 8.1 7.9 6.8 POLI "RAD30B, RAD3OB" ENSG00000101751 "DNA polymerase iota" Q9UNA4 18 54269404-54321266 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012000, HPA064696" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" "Nuclear speckles" "Cytoplasmic bodies" "HPA012000: AB_1847786, HPA064696: " "unprognostic (1.64e-1)" "unprognostic (5.79e-3)" "unprognostic (9.72e-3)" "unprognostic (4.92e-2)" "unprognostic (3.04e-1)" "unprognostic (4.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.05e-2)" "unprognostic (4.04e-3)" "unprognostic (2.22e-2)" "unprognostic (2.07e-3)" "unprognostic (1.30e-3)" "unprognostic (1.55e-1)" "unprognostic (4.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (6.99e-2)" 16.5 11.1 10.2 9.5 14.0 5.2 15.8 9.6 14.7 12.9 9.9 13.4 13.7 6.6 13.2 13.1 6.6 10.3 8.3 9.1 8.7 7.6 12.9 6.4 9.0 7.4 10.9 9.0 16.4 11.8 17.6 21.3 17.4 15.3 12.7 7.7 9.6 11.3 14.7 7.2 8.2 7.6 10.9 12.0 8.2 9.0 30.5 10.9 17.3 27.3 1.5 7.0 12.7 10.5 9.9 10.3 10.9 10.7 7.9 12.7 7.1 7.7 2.8 21.3 12.9 7.2 14.1 6.9 6.4 13.8 7.4 12.4 2.1 7.4 3.7 2.1 9.3 6.4 5.0 7.3 8.3 8.8 2.5 4.6 3.2 5.4 11.8 7.3 3.8 15.2 11.2 6.4 13.4 15.6 3.1 10.5 12.3 6.1 5.2 6.4 7.3 3.1 3.3 4.3 9.1 8.4 10.3 10.0 10.2 4.6 4.1 6.8 14.8 3.3 7.5 13.9 3.8 2.1 5.3 8.5 1.9 5.2 9.9 6.6 10.1 5.4 10.7 10.9 8.3 5.7 7.7 8.6 8.8 8.6 10.3 9.9 12.7 7.6 6.7 7.9 5.8 8.1 9.8 7.1 10.2 14.0 9.6 14.7 8.7 7.6 10.9 9.0 15.3 10.9 POLK "DINB1, DINP, POLQ" ENSG00000122008 "DNA polymerase kappa" Q9UBT6 5 75511756-75601144 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012035, HPA057303, HPA068117, HPA069375" Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA012035: , HPA057303: , HPA068117: , HPA069375: " "unprognostic (9.66e-2)" "unprognostic (5.29e-2)" "unprognostic (5.37e-2)" "unprognostic (2.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.66e-1)" "unprognostic (1.73e-2)" "unprognostic (7.76e-2)" "unprognostic (1.65e-2)" "unprognostic (6.29e-3)" "unprognostic (2.42e-1)" "unprognostic (5.93e-2)" "unprognostic (1.80e-2)" "unprognostic (9.96e-3)" "unprognostic (1.58e-1)" "unprognostic (9.64e-2)" "unprognostic (2.02e-1)" 14.7 12.7 10.1 8.6 12.9 6.3 13.4 17.0 13.4 18.1 10.7 8.8 13.6 6.3 21.3 12.1 11.7 10.5 9.5 11.4 14.1 10.5 12.6 12.3 12.2 9.2 14.1 12.9 15.5 11.1 18.5 23.9 15.2 17.2 13.9 8.1 6.5 10.2 10.5 15.2 10.3 9.2 15.4 16.9 13.1 9.0 9.8 12.4 12.1 18.8 9.3 8.9 12.7 10.2 7.0 7.5 6.0 13.3 4.6 4.5 2.5 6.4 6.6 4.1 5.2 5.4 10.9 3.5 12.3 8.7 9.6 10.0 4.2 5.2 6.6 10.1 8.1 2.5 3.8 4.2 11.5 7.3 4.4 6.0 5.8 1.9 10.4 3.8 4.9 5.0 5.2 7.7 5.3 8.0 5.3 3.9 9.0 0.5 7.5 3.1 1.5 3.9 3.2 10.5 4.6 5.8 2.2 4.2 4.6 9.2 2.5 3.3 3.6 3.7 10.0 7.0 3.6 3.3 7.0 4.5 4.1 5.9 4.7 6.1 12.0 5.7 7.1 3.4 3.3 7.9 2.9 7.0 3.7 4.0 6.1 5.4 4.5 3.0 6.0 4.6 13.3 7.5 4.1 2.5 10.1 12.9 17.0 13.4 14.1 10.5 14.1 12.9 17.2 12.4 POLL ENSG00000166169 "DNA polymerase lambda" Q9UGP5 10 101578882-101588270 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066704 Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" "Nucleoplasm, Golgi apparatus" "HPA066704: " "unprognostic (3.71e-3)" "unprognostic (6.93e-3)" "unprognostic (1.73e-2)" "unprognostic (2.47e-2)" "unprognostic (9.52e-2)" "unprognostic (1.80e-2)" "unprognostic (2.11e-2)" "unprognostic (1.24e-1)" "unprognostic (8.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.12e-2)" "unprognostic (7.19e-2)" "unprognostic (4.74e-2)" "unprognostic (1.06e-2)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" "unprognostic (1.64e-3)" 11.0 15.1 14.4 16.0 17.1 9.2 13.4 11.2 22.1 13.7 12.6 16.4 15.6 14.3 15.1 22.1 15.4 18.1 17.7 12.3 11.1 10.4 16.4 16.5 11.8 13.0 9.6 13.0 20.9 30.7 21.7 23.7 11.7 12.7 17.2 15.0 19.5 17.8 14.7 26.1 12.8 11.9 12.7 9.4 15.6 16.7 53.2 11.2 4.6 18.3 10.2 14.2 14.8 11.6 8.5 10.7 1.1 8.5 8.4 11.9 7.1 12.5 11.5 9.1 12.6 9.2 17.2 12.7 8.3 14.5 12.8 13.5 8.4 15.2 3.1 13.2 7.5 15.8 10.0 12.3 10.3 11.1 13.6 9.8 10.8 9.5 17.0 10.2 9.0 15.6 16.8 14.1 29.4 13.7 10.9 10.9 8.0 10.0 0.0 11.2 4.8 6.8 0.0 8.1 5.1 10.7 7.6 6.4 9.3 5.1 8.6 14.3 26.2 5.9 7.3 4.6 9.3 5.2 9.1 15.8 7.9 4.7 9.9 8.9 3.4 0.5 8.5 1.1 6.7 5.9 10.6 8.5 7.4 6.8 10.7 7.1 11.9 7.9 0.9 8.4 5.7 0.2 8.9 7.1 14.4 17.1 11.2 22.1 11.1 10.4 9.6 13.0 12.7 11.2 POLM Tdt-N ENSG00000122678 "DNA polymerase mu" Q9NP87 7 44072247-44082540 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 31.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 31.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058900, HPA066007" Supported Nucleoplasm Nucleoplasm "HPA058900: , HPA066007: " "unprognostic (2.44e-2)" "unprognostic (8.18e-2)" "unprognostic (2.21e-3)" "unprognostic (3.93e-2)" "unprognostic (5.40e-2)" "unprognostic (1.83e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (3.91e-1)" "unprognostic (9.36e-2)" "unprognostic (8.26e-2)" "unprognostic (2.46e-3)" "unprognostic (6.31e-2)" "unprognostic (1.47e-1)" "unprognostic (2.87e-1)" "unprognostic (3.87e-3)" 10.7 8.7 7.0 18.0 7.1 7.6 12.2 11.9 8.8 13.8 11.2 11.1 11.7 12.2 10.1 12.0 11.7 11.8 11.8 10.8 6.8 4.4 13.0 12.5 10.1 20.9 9.9 7.0 13.8 12.3 10.0 9.0 8.1 8.2 11.8 7.1 12.4 13.5 14.3 11.2 12.0 12.6 8.9 9.0 18.7 12.0 6.8 8.1 30.1 15.4 8.3 17.6 12.4 10.7 5.9 4.8 31.6 2.1 3.5 4.2 1.3 1.0 1.5 1.5 3.4 2.2 2.5 4.9 3.5 3.9 2.7 1.6 1.9 2.6 11.1 3.5 2.9 3.3 1.6 37.7 1.5 3.9 3.5 1.3 1.6 0.7 3.1 3.4 5.0 4.0 3.6 2.2 2.8 4.8 1.6 5.4 2.3 2.5 7.0 3.0 3.3 8.1 5.6 0.9 4.4 3.0 1.8 1.6 2.9 1.7 7.2 3.6 4.6 6.0 3.3 1.9 2.8 1.9 5.1 8.9 4.4 8.7 3.5 3.1 4.6 8.6 1.8 5.1 3.3 2.1 3.3 4.0 2.9 3.0 1.6 5.9 4.2 3.4 31.6 3.5 1.6 4.8 2.7 1.3 7.0 7.1 11.9 8.8 6.8 4.4 9.9 7.0 8.2 8.1 POLN ENSG00000130997 "DNA polymerase nu" Q7Z5Q5 4 2071918-2242121 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 5.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "eosinophil: 2.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035939, HPA035940" Enhanced Nucleoplasm Nucleoplasm "HPA035939: , HPA035940: " "unprognostic (8.52e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (1.45e-2)" "unprognostic (3.46e-1)" "unprognostic (2.70e-1)" "unprognostic (5.83e-2)" "unprognostic (2.23e-1)" "unprognostic (2.02e-3)" "unprognostic (1.25e-1)" "unprognostic (1.49e-3)" "unprognostic (9.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" 13.6 3.9 6.1 2.5 5.7 1.8 5.2 11.1 5.5 2.8 2.9 3.5 2.9 2.7 4.0 5.8 2.6 3.6 3.3 2.8 4.4 2.9 3.6 3.4 3.0 2.7 4.3 4.0 2.8 3.1 2.4 7.6 2.3 3.8 4.6 1.8 1.7 4.7 3.5 2.7 2.7 2.4 3.3 5.6 3.5 2.9 12.3 5.2 8.5 2.4 0.9 2.6 2.5 2.6 0.2 0.1 2.4 0.0 0.0 0.9 0.1 0.3 2.7 0.5 1.9 5.7 2.2 0.0 1.9 1.0 1.1 1.6 0.1 0.2 1.2 0.5 1.7 0.4 2.2 0.8 1.6 0.3 2.9 0.1 1.9 0.0 0.7 0.2 2.5 3.0 0.8 1.6 1.4 0.6 0.2 2.3 3.1 0.3 0.2 0.2 0.2 0.5 0.0 3.8 0.9 0.8 0.5 2.5 0.0 0.2 0.0 0.2 0.0 0.7 0.3 0.1 1.9 1.1 0.6 0.6 0.7 0.0 0.6 1.8 1.1 0.0 0.0 2.4 0.2 0.0 0.9 0.2 0.2 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.1 6.1 5.7 11.1 5.5 4.4 2.9 4.3 4.0 3.8 5.2 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.5;lymphoid tissue: 21.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 1.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 5.2" "HPA048931, HPA053359" Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA048931: , HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavourable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favourable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.5 0.8 0.2 8.2 0.7 9.5 0.6 0.6 0.4 0.9 3.5 0.2 0.8 2.0 0.9 0.6 6.0 0.3 0.4 0.8 0.3 0.2 0.4 0.6 0.9 4.7 0.3 0.0 0.4 0.4 0.0 0.2 2.8 0.3 0.4 3.7 0.1 1.1 0.8 1.2 2.4 3.9 0.5 0.4 2.6 1.1 5.8 0.6 21.4 0.3 5.6 7.5 0.6 1.7 0.5 1.1 1.6 0.4 0.0 0.4 0.0 13.3 9.1 7.8 5.5 0.7 0.9 7.1 6.3 2.4 7.5 10.1 7.2 5.0 15.9 2.9 3.4 10.6 9.2 4.1 12.8 4.6 5.0 10.2 5.6 4.5 0.0 11.0 9.3 0.1 0.3 6.8 4.2 3.7 6.7 12.1 7.8 5.2 9.9 6.4 7.4 4.4 8.4 9.4 5.6 2.4 7.7 4.3 3.8 7.3 4.0 2.6 3.7 10.9 2.8 6.6 8.7 2.6 8.2 6.1 4.9 16.5 3.2 8.2 4.9 1.6 0.2 0.0 0.3 0.2 0.0 0.3 0.4 0.3 0.4 0.5 0.0 0.2 0.0 0.0 0.4 1.1 0.1 0.0 0.2 0.7 0.6 0.4 0.3 0.2 0.3 0.0 0.3 0.6 POLR1A "DKFZP586M0122, FLJ21915, RPA1, RPO1-4" ENSG00000068654 "RNA polymerase I subunit A" O95602 2 86020216-86106155 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010145, HPA031513, HPA049700" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Intermediate filaments" "Nucleoli fibrillar center" "Nucleoplasm, Intermediate filaments" "CAB010145: AB_675814, HPA031513: , HPA049700: " "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "unprognostic (1.32e-1)" "unprognostic (1.93e-1)" "prognostic unfavourable (3.70e-9)" "unprognostic (1.06e-2)" "unprognostic (1.35e-1)" "prognostic unfavourable (3.37e-4)" "unprognostic (4.31e-2)" "unprognostic (4.56e-2)" "unprognostic (3.27e-1)" "unprognostic (2.20e-3)" "unprognostic (1.94e-1)" "prognostic unfavourable (8.41e-4)" "unprognostic (7.20e-2)" 14.3 12.9 10.1 12.4 16.5 9.7 10.3 12.2 20.3 11.1 11.0 17.4 8.3 9.4 19.5 7.4 13.5 12.3 11.7 12.7 9.0 9.2 11.5 15.1 9.4 9.6 9.0 9.4 12.6 14.3 18.2 15.9 11.4 13.8 10.7 11.8 13.9 11.2 12.5 22.5 12.3 8.6 16.0 8.0 11.2 10.4 14.9 10.9 14.0 10.3 11.4 14.2 10.9 9.6 2.6 2.6 1.8 2.5 2.0 3.8 1.2 9.3 21.3 9.5 18.3 9.3 7.5 13.8 8.6 5.7 12.4 7.7 26.7 7.4 21.5 9.2 8.8 10.9 24.5 12.7 11.1 8.9 12.6 18.5 9.1 17.9 6.6 17.5 10.0 5.7 8.0 18.4 14.4 9.6 24.5 5.4 8.5 8.3 12.9 7.5 17.3 14.1 15.6 20.9 10.0 5.5 15.4 14.8 7.7 9.5 12.6 6.8 7.4 6.1 15.2 15.1 11.9 12.8 17.3 7.7 7.4 18.8 7.8 15.1 13.3 1.8 1.5 0.2 3.0 2.5 3.8 2.0 1.5 2.5 1.8 2.6 1.4 1.8 0.7 2.0 1.9 2.6 0.7 1.2 10.1 16.5 12.2 20.3 9.0 9.2 9.0 9.4 13.8 10.9 POLR1B "FLJ10816, FLJ21921, RPA2, Rpo1-2" ENSG00000125630 "RNA polymerase I subunit B" Q9H9Y6 2 112541915-112577150 "Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037528 Supported Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA037528: AB_10671627" "unprognostic (1.66e-1)" "unprognostic (3.17e-2)" "unprognostic (2.55e-1)" "prognostic unfavourable (2.71e-5)" "unprognostic (2.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.98e-3)" "unprognostic (1.98e-1)" "unprognostic (2.05e-1)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.52e-4)" "unprognostic (6.12e-2)" "unprognostic (1.29e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (3.56e-2)" 8.8 11.0 6.4 10.6 6.8 4.9 15.7 8.0 8.2 7.6 7.0 7.7 8.6 5.8 9.3 7.4 12.8 9.2 9.2 6.1 5.7 6.1 11.3 20.5 8.0 11.3 6.8 3.7 11.3 25.2 20.7 11.5 7.2 5.2 7.7 8.5 7.3 10.0 8.3 14.7 9.2 8.0 7.9 4.8 11.4 8.1 15.7 5.0 9.6 15.7 11.5 14.6 8.9 11.8 9.4 11.0 2.5 6.3 10.2 17.1 7.3 9.4 9.9 6.3 13.0 6.8 6.6 11.8 7.1 5.4 12.0 10.5 22.2 5.6 22.7 10.6 4.7 13.3 26.4 14.5 13.9 10.2 13.3 13.1 9.9 16.7 7.2 20.9 9.1 6.2 10.5 12.5 19.3 9.3 23.7 8.2 6.3 8.3 9.4 13.6 30.6 19.7 14.2 10.4 24.1 8.3 9.0 15.9 14.8 6.5 16.5 9.0 7.6 7.4 8.4 7.4 10.9 6.8 10.4 11.1 18.3 19.6 5.6 13.4 6.2 0.2 6.0 2.5 8.3 6.3 17.1 9.4 8.4 8.9 11.0 9.3 10.3 10.4 0.4 10.2 4.8 2.6 11.3 7.3 6.4 6.8 8.0 8.2 5.7 6.1 6.8 3.7 5.2 5.0 POLR1C "RPA39, RPA40, RPA5, RPAC1" ENSG00000171453 "RNA polymerase I subunit C" O15160 6 43509702-43562419 "Disease related genes, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031010 Supported Nucleoplasm Nucleoplasm "HPA031010: AB_10603131" "unprognostic (2.84e-1)" "unprognostic (1.67e-1)" "unprognostic (3.15e-1)" "unprognostic (6.57e-2)" "unprognostic (7.01e-2)" "unprognostic (3.59e-1)" "unprognostic (6.69e-3)" "unprognostic (1.09e-3)" "unprognostic (2.00e-3)" "unprognostic (1.90e-2)" "unprognostic (2.05e-1)" "unprognostic (7.32e-2)" "prognostic unfavourable (4.17e-4)" "unprognostic (1.20e-2)" "unprognostic (4.69e-2)" "unprognostic (3.01e-1)" "unprognostic (6.41e-2)" 16.2 20.8 11.8 15.6 18.6 7.4 22.1 11.8 19.2 19.1 19.1 16.4 14.1 14.0 22.5 18.0 24.0 23.3 14.5 12.7 11.7 13.3 26.9 26.6 12.4 13.5 12.4 10.3 22.9 30.7 14.2 20.5 18.5 13.4 19.3 17.4 19.1 24.1 15.4 17.5 21.9 12.8 16.2 9.9 21.3 16.1 20.9 11.4 17.4 35.2 18.3 27.9 16.3 16.8 23.0 18.6 2.1 13.4 17.5 26.2 14.7 24.7 20.7 9.1 24.6 14.0 15.2 14.4 15.2 11.3 17.1 14.6 27.4 8.4 28.2 16.6 14.7 15.1 21.9 19.3 19.9 14.8 22.9 19.2 20.9 37.9 17.6 29.3 13.5 13.5 18.8 23.3 29.6 13.3 44.1 8.3 14.9 34.9 15.2 21.2 16.8 17.9 10.4 14.3 18.9 20.5 34.8 16.8 11.3 13.3 11.6 20.1 12.5 25.9 15.9 12.3 16.5 13.1 23.9 12.0 26.5 47.0 8.3 20.1 13.5 2.1 13.4 1.9 16.0 10.3 21.7 21.6 19.0 15.8 18.6 23.0 26.2 23.5 1.3 17.5 8.3 16.9 13.6 14.7 11.8 18.6 11.8 19.2 11.7 13.3 12.4 10.3 13.4 11.4 POLR1D "MGC9850, RPA16, RPA9, RPAC2, RPO1-3" ENSG00000186184 "RNA polymerase I subunit D" "P0DPB5, P0DPB6" 13 27620742-27744237 "Disease related genes, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039337 Uncertain Approved "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA039337: AB_10672961" "unprognostic (1.33e-3)" "unprognostic (5.96e-2)" "unprognostic (4.35e-2)" "unprognostic (8.50e-3)" "unprognostic (1.98e-2)" "unprognostic (3.71e-3)" "unprognostic (5.33e-3)" "unprognostic (2.04e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-2)" "unprognostic (2.80e-1)" "unprognostic (5.18e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (2.56e-2)" "unprognostic (8.28e-2)" "unprognostic (6.45e-2)" 30.5 43.8 17.0 35.4 22.1 46.5 36.5 41.2 23.7 34.6 40.8 15.9 34.4 30.9 26.0 29.9 58.9 21.4 32.3 28.5 16.7 14.4 27.3 29.9 32.6 36.5 14.8 20.6 43.6 115.9 16.7 24.3 24.7 15.6 37.4 32.7 20.9 46.2 39.5 38.1 44.8 36.4 41.2 17.4 31.9 41.7 23.7 13.0 50.9 32.3 40.7 40.7 56.8 54.0 29.2 42.7 21.4 39.3 27.9 56.6 26.2 20.0 18.9 21.8 22.3 25.1 45.1 29.3 19.9 34.4 26.3 26.2 30.5 40.9 65.0 15.1 22.4 31.0 40.0 63.5 31.4 20.1 23.8 46.2 20.6 51.0 37.9 41.9 36.3 40.5 67.2 21.4 40.0 36.4 25.2 11.6 25.5 20.8 41.2 51.1 52.5 20.1 28.3 37.5 29.2 41.5 31.2 37.2 29.1 13.3 26.8 71.7 16.4 39.2 25.2 11.7 18.3 20.0 21.7 19.0 21.5 36.7 10.2 30.4 22.7 21.4 38.4 17.3 24.9 39.3 32.8 28.4 40.2 31.4 42.7 29.2 43.6 34.2 13.7 27.9 34.2 31.2 56.6 26.2 17.0 22.1 41.2 23.7 16.7 14.4 14.8 20.6 15.6 13.0 POLR1E "FLJ13390, FLJ13970, PAF53, PRAF1" ENSG00000137054 "RNA polymerase I subunit E" Q9GZS1 9 37485935-37503697 "Predicted intracellular proteins, Predicted membrane proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022527, HPA052400" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "HPA022527: AB_1854924, HPA052400: " "prognostic favourable (2.27e-4)" "unprognostic (2.09e-1)" "unprognostic (9.90e-3)" "unprognostic (1.10e-2)" "unprognostic (7.16e-3)" "unprognostic (2.07e-1)" "unprognostic (1.09e-2)" "unprognostic (7.14e-2)" "unprognostic (1.04e-1)" "unprognostic (2.48e-1)" "unprognostic (2.80e-1)" "unprognostic (2.48e-1)" "unprognostic (1.07e-1)" "unprognostic (4.96e-2)" "unprognostic (5.23e-1)" "unprognostic (1.58e-1)" "unprognostic (4.24e-2)" 15.4 12.2 10.5 20.2 11.6 9.3 19.7 10.7 9.0 19.0 13.9 10.0 14.9 7.0 20.5 14.7 15.1 17.3 13.7 14.9 9.1 9.2 7.6 23.9 10.1 15.5 9.0 9.2 36.9 25.9 10.3 9.6 8.7 9.5 17.3 9.3 9.5 19.5 18.4 17.2 13.1 9.0 22.4 10.2 10.8 13.0 11.2 11.5 16.0 15.3 13.3 17.1 21.9 16.8 8.1 3.9 1.4 4.3 9.0 16.9 5.5 19.4 18.3 10.1 16.0 19.0 24.4 6.6 17.2 6.7 17.9 15.9 15.7 6.5 28.3 8.4 19.9 8.2 24.6 20.5 22.7 27.3 11.5 13.5 23.2 11.1 14.2 25.9 9.6 25.9 7.3 35.1 30.3 9.1 35.3 12.5 15.7 9.3 17.9 8.9 17.9 15.0 16.0 9.3 13.5 9.3 7.2 14.5 11.9 11.5 9.2 14.8 9.0 17.3 6.2 21.3 32.5 18.2 34.4 6.8 9.6 29.8 7.3 16.5 17.6 0.0 2.5 1.4 10.6 4.3 16.9 7.4 10.2 10.8 3.9 8.1 12.8 11.1 0.8 9.0 3.4 2.7 5.4 5.5 10.5 11.6 10.7 9.0 9.1 9.2 9.0 9.2 9.5 11.5 POLR2A "POLR2, POLRA, RPB1" ENSG00000181222 "RNA polymerase II subunit A" P24928 17 7484366-7514616 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription" "DNA-binding, Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEK 293: 3.0;HL-60: 2.6;HMC-1: 3.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 4.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.9" "CAB012226, CAB016388, CAB022311" Enhanced Approved Nucleoplasm Nucleoplasm "CAB012226: AB_304749, CAB016388: AB_677353, CAB022311: " "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (1.58e-1)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (5.43e-2)" "unprognostic (8.77e-3)" "unprognostic (1.48e-1)" "unprognostic (5.19e-3)" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "unprognostic (3.70e-2)" "unprognostic (1.01e-3)" "unprognostic (1.25e-1)" "unprognostic (2.30e-2)" "unprognostic (1.49e-1)" "unprognostic (4.70e-2)" 5.0 5.9 4.5 5.7 7.4 26.4 8.5 5.8 7.8 7.2 4.3 4.8 4.5 4.3 5.5 5.4 7.0 4.6 4.2 4.5 6.0 3.5 4.6 4.4 6.4 11.5 4.7 4.2 5.2 5.8 5.4 4.8 4.2 5.4 4.3 4.9 6.3 5.5 8.1 6.6 6.6 6.0 4.5 6.1 6.2 5.3 13.2 2.9 15.0 5.6 4.1 5.0 5.3 4.6 0.7 0.7 4.9 1.0 0.0 1.2 0.0 0.3 0.0 0.3 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.4 0.1 0.5 0.0 0.2 0.0 0.2 0.4 3.0 0.7 1.2 0.2 0.0 2.6 3.9 0.4 0.0 0.3 0.0 0.2 0.3 0.0 0.5 0.0 0.1 0.8 0.4 0.9 1.1 0.0 0.0 0.0 1.4 0.3 0.9 1.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.5 0.8 0.4 0.2 0.4 0.0 0.6 0.3 3.0 0.5 0.6 1.2 0.4 0.3 0.3 0.5 0.4 0.1 0.7 0.6 0.5 4.9 0.0 1.0 0.7 0.5 0.0 4.5 7.4 5.8 7.8 6.0 3.5 4.7 4.2 5.4 2.9 POLR2B RPB2 ENSG00000047315 "RNA polymerase II subunit B" P30876 4 56977722-57031168 "Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037506 Supported Supported Nucleoplasm Nucleoplasm "HPA037506: AB_10672597" "unprognostic (9.88e-3)" "unprognostic (4.38e-2)" "unprognostic (1.83e-3)" "unprognostic (7.51e-2)" "unprognostic (2.30e-2)" "unprognostic (4.21e-3)" "unprognostic (1.24e-3)" "unprognostic (3.51e-1)" "unprognostic (6.39e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-1)" "unprognostic (1.95e-1)" "prognostic favourable (7.17e-4)" "unprognostic (1.91e-1)" "unprognostic (1.51e-1)" "unprognostic (3.43e-1)" "unprognostic (7.35e-2)" 24.5 34.3 31.1 34.6 31.0 21.4 24.8 43.8 33.3 25.9 26.0 18.8 24.9 22.5 35.1 21.4 27.4 28.3 21.2 32.9 29.3 21.7 26.2 21.4 21.2 32.4 28.0 30.2 26.4 28.1 40.7 37.3 25.4 28.3 24.8 26.5 18.4 30.5 28.2 61.8 24.4 27.3 27.6 26.4 27.1 28.8 26.6 26.8 33.4 27.0 34.7 35.1 31.5 22.4 19.8 15.2 27.8 13.9 18.0 23.8 12.7 24.7 20.7 37.4 31.6 30.9 27.9 20.0 33.0 33.6 33.1 31.0 26.3 25.0 38.6 31.3 30.5 17.6 44.9 25.1 47.4 18.3 20.1 29.0 23.1 22.9 35.8 49.9 33.6 30.0 25.3 37.8 23.1 39.4 43.1 33.0 38.1 18.1 47.0 19.3 30.8 24.3 34.3 24.6 21.2 22.6 28.2 31.2 35.0 20.5 39.1 28.4 21.0 27.8 28.7 24.1 32.4 25.2 43.3 26.6 25.3 56.3 27.5 27.0 29.8 27.8 12.2 16.8 20.7 12.4 22.0 19.8 20.3 21.4 15.2 14.4 19.9 23.8 11.3 18.0 13.9 12.9 20.9 12.7 31.1 31.0 43.8 33.3 29.3 21.7 28.0 30.2 28.3 26.8 POLR2C RPB3 ENSG00000102978 "RNA polymerase II subunit C" P19387 16 57462387-57472010 "Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040919, HPA041826" Enhanced Supported Nucleoplasm,Microtubules,Cytosol Nucleoplasm "Microtubules, Cytosol" "HPA040919: AB_10795483, HPA041826: AB_10793935" "unprognostic (2.10e-2)" "unprognostic (4.42e-2)" "unprognostic (7.52e-3)" "unprognostic (1.82e-2)" "unprognostic (1.34e-1)" "prognostic unfavourable (1.48e-4)" "unprognostic (2.90e-1)" "unprognostic (9.54e-2)" "unprognostic (1.95e-1)" "unprognostic (2.48e-2)" "unprognostic (2.60e-2)" "unprognostic (6.63e-2)" "prognostic favourable (3.03e-6)" "unprognostic (2.29e-1)" "unprognostic (2.31e-2)" "unprognostic (1.20e-1)" "unprognostic (5.43e-3)" 26.2 30.1 24.2 18.4 26.9 23.9 25.8 34.1 37.6 27.2 22.9 28.8 23.1 21.5 26.0 45.0 26.2 30.3 29.9 32.6 24.5 25.9 38.3 44.8 29.9 30.2 25.0 30.1 37.2 39.4 33.7 35.0 29.2 25.5 29.2 26.0 29.6 30.4 31.4 47.5 23.7 27.9 26.1 24.1 22.4 25.2 26.4 21.9 30.5 35.8 27.3 27.1 27.5 22.2 21.8 16.2 41.7 19.8 26.2 28.6 21.9 17.4 28.8 24.1 21.9 21.9 19.7 21.4 23.0 25.1 37.0 24.5 36.8 22.1 19.7 27.1 25.3 18.3 31.9 24.2 41.2 9.1 23.7 15.1 17.2 42.0 24.9 27.4 29.1 17.6 20.0 28.2 26.1 22.2 26.2 11.1 24.1 24.1 30.3 29.0 36.1 43.9 44.3 28.6 34.9 29.9 17.3 30.7 35.8 37.3 20.8 24.1 15.9 25.3 17.1 23.4 23.8 17.7 26.2 25.8 22.0 40.1 23.5 23.7 30.8 24.8 17.3 29.0 20.7 16.4 22.6 21.8 23.6 19.1 16.2 20.9 28.6 26.8 41.7 26.2 19.8 13.2 22.5 21.9 24.2 26.9 34.1 37.6 24.5 25.9 25.0 30.1 25.5 21.9 POLR2D RBP4 ENSG00000144231 "RNA polymerase II subunit D" O15514 2 127843551-127858157 "Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 46.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034694, HPA046092" Approved Supported "Nucleoplasm,Nuclear speckles" "Nucleoplasm, Nuclear speckles" "HPA034694: , HPA046092: AB_10963049" "unprognostic (3.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.59e-1)" "unprognostic (2.54e-2)" "unprognostic (2.77e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (8.91e-4)" "unprognostic (2.51e-1)" "unprognostic (7.95e-3)" "unprognostic (2.64e-3)" "unprognostic (1.97e-1)" "unprognostic (2.51e-1)" "prognostic unfavourable (2.79e-4)" "unprognostic (3.66e-2)" "unprognostic (6.57e-2)" "unprognostic (1.17e-1)" "unprognostic (2.38e-1)" 8.2 9.4 8.1 8.9 9.1 17.9 7.9 9.3 12.6 6.9 7.7 12.3 6.9 6.3 7.5 6.2 9.8 7.7 7.6 7.3 7.8 6.3 6.3 13.5 7.2 11.8 9.9 7.5 10.3 17.4 7.4 9.4 10.2 8.7 7.2 9.9 7.3 7.6 6.5 21.9 8.9 7.8 9.8 8.8 11.1 7.8 46.4 9.9 16.7 6.3 9.1 16.8 8.0 7.2 16.7 20.6 11.4 22.1 16.7 21.0 14.3 18.2 11.9 22.2 15.5 8.3 9.1 17.8 17.5 8.3 21.1 18.9 26.9 15.1 28.4 15.1 11.7 9.7 31.8 15.1 32.8 16.6 17.3 28.0 11.9 24.7 9.7 30.0 15.6 6.4 11.4 28.2 16.2 13.7 39.0 25.5 12.0 14.5 29.8 13.7 31.1 13.8 28.7 23.5 25.5 7.0 12.5 13.8 18.5 11.8 14.6 14.7 16.3 20.8 13.8 18.3 25.8 10.3 20.1 30.1 48.7 51.0 15.9 15.0 18.0 5.7 15.8 11.4 19.4 21.5 18.1 16.7 15.6 16.9 20.6 15.1 21.0 17.8 5.0 16.7 22.1 13.5 13.9 14.3 8.1 9.1 9.3 12.6 7.8 6.3 9.9 7.5 8.7 9.9 POLR2E "hRPB25, hsRPB5, RPABC1, RPB5, XAP4" ENSG00000099817 "RNA polymerase II subunit E" P19388 19 1086579-1095380 "Predicted intracellular proteins, RNA polymerase related proteins" "Host-virus interaction, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063030, HPA068992" Supported Supported Nucleoplasm Nucleoplasm "HPA063030: AB_2684926, HPA068992: AB_2686065" "unprognostic (2.52e-1)" "unprognostic (3.73e-2)" "unprognostic (2.49e-1)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (6.42e-2)" "unprognostic (2.59e-3)" "unprognostic (1.60e-1)" "unprognostic (2.08e-1)" "unprognostic (2.05e-1)" "unprognostic (2.03e-3)" "unprognostic (3.03e-2)" "prognostic favourable (3.21e-6)" "unprognostic (3.22e-1)" "unprognostic (1.47e-1)" "unprognostic (1.72e-3)" "unprognostic (4.77e-2)" 41.4 26.2 29.6 22.8 27.9 19.8 27.6 19.0 36.9 20.1 26.5 18.6 18.4 20.1 21.4 22.6 34.1 26.3 25.8 27.6 29.6 26.3 34.0 57.9 25.1 25.1 30.1 22.6 22.0 21.0 39.7 13.0 26.4 33.4 24.3 29.5 20.3 17.9 18.9 33.2 23.7 26.9 25.7 22.1 23.1 21.5 29.3 15.5 31.9 30.6 21.1 36.7 22.1 20.6 12.8 28.2 17.9 30.4 16.7 17.5 20.9 14.3 13.3 18.7 14.9 25.7 16.0 8.7 10.7 14.8 17.7 10.4 15.6 5.3 12.1 4.8 31.6 11.7 35.0 11.8 33.0 12.5 10.6 15.8 16.6 14.3 10.2 23.1 11.9 11.7 7.7 12.3 23.4 16.2 17.7 13.8 19.8 11.9 12.7 7.2 15.0 10.2 13.6 18.5 11.5 18.1 16.7 9.5 10.8 17.8 12.5 7.4 13.1 10.8 22.0 9.0 10.0 16.2 12.3 21.4 28.5 21.1 14.7 15.0 10.2 12.1 30.4 17.9 16.4 20.5 17.5 11.7 15.5 17.2 28.2 12.8 12.4 12.7 16.1 16.7 22.2 19.6 14.7 20.9 29.6 27.9 19.0 36.9 29.6 26.3 30.1 22.6 33.4 15.5 POLR2F "HRBP14.4, RPB6" ENSG00000100142 "RNA polymerase II subunit F" P61218 22 37952607-38041915 "Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Cancer enhanced" "Detected in single" "melanoma: 1.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000827, CAB009882" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "CAB009882: AB_2299942, HPA000827: AB_1079834" "unprognostic (8.27e-2)" "unprognostic (7.50e-2)" "unprognostic (1.51e-3)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (2.73e-3)" "unprognostic (2.85e-1)" "unprognostic (5.87e-2)" "unprognostic (4.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.11e-4)" "unprognostic (9.08e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-1)" "unprognostic (7.86e-2)" 31.7 31.4 37.5 23.4 43.8 23.0 28.2 32.6 54.5 25.2 27.8 57.3 20.4 26.3 24.2 18.7 24.6 23.2 20.3 37.8 33.5 31.2 25.1 58.5 17.9 19.8 44.8 44.1 30.2 26.1 43.5 28.8 21.2 38.4 21.4 21.0 21.0 38.0 29.6 67.9 19.0 25.7 20.8 39.6 16.8 26.9 21.9 48.3 13.1 28.5 23.4 18.0 19.0 26.8 36.1 49.5 52.4 36.7 40.1 38.5 29.3 34.0 40.3 28.5 30.4 34.3 20.1 25.4 31.9 18.7 32.8 30.9 46.7 12.1 26.3 23.1 27.6 24.6 39.2 30.9 16.2 32.1 66.3 24.5 41.4 63.4 29.9 47.8 15.8 26.6 23.5 44.2 17.1 28.0 46.8 22.2 23.7 48.4 37.2 57.7 41.0 30.7 37.1 26.2 30.7 18.1 21.2 42.8 16.0 29.4 21.1 46.1 14.7 33.2 25.6 28.9 41.1 35.7 36.1 25.1 38.8 54.9 29.4 24.4 32.5 34.5 36.7 52.4 34.3 33.3 32.1 36.1 30.0 33.2 33.4 28.9 27.3 27.2 46.2 40.1 28.1 49.5 38.5 29.3 37.5 43.8 32.6 42.7 33.5 31.2 44.8 44.1 38.4 48.3 POLR2G "hRPB19, hsRPB7, RPB7" ENSG00000168002 "RNA polymerase II subunit G" P62487 11 62761544-62766710 "Predicted intracellular proteins, RNA polymerase related proteins" Transcription RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053000 Approved Supported Nucleoplasm Nucleoplasm "HPA053000: " "unprognostic (7.58e-3)" "unprognostic (2.75e-1)" "unprognostic (2.37e-2)" "prognostic favourable (8.23e-4)" "unprognostic (1.39e-1)" "unprognostic (2.16e-2)" "prognostic unfavourable (6.02e-5)" "unprognostic (8.50e-2)" "unprognostic (6.01e-2)" "unprognostic (6.26e-3)" "unprognostic (9.41e-2)" "unprognostic (1.85e-1)" "prognostic unfavourable (1.11e-4)" "unprognostic (1.53e-1)" "unprognostic (1.64e-1)" "unprognostic (2.46e-1)" "unprognostic (2.21e-1)" 27.9 34.6 39.4 28.7 37.7 29.4 37.2 18.6 33.5 28.0 25.4 39.9 25.0 17.3 27.0 44.0 27.4 32.3 25.2 25.0 35.0 27.7 30.6 32.1 29.8 47.5 41.4 27.6 28.1 29.0 29.6 20.4 29.0 30.7 28.3 32.9 31.4 22.3 27.2 18.9 27.5 19.5 32.6 45.4 30.7 22.6 18.7 33.6 47.7 28.2 26.3 49.2 25.4 23.2 48.9 61.3 51.5 54.1 46.4 47.4 64.6 25.0 44.7 48.3 30.2 25.3 24.6 12.0 17.8 22.6 43.0 34.2 27.0 29.2 36.4 41.4 27.0 24.5 21.9 33.6 38.3 69.4 27.5 24.0 35.6 31.6 35.5 31.9 22.0 24.0 34.0 19.9 40.6 33.5 30.0 24.0 30.4 78.7 46.2 42.0 29.9 45.8 38.1 44.2 47.8 31.7 21.4 20.2 34.3 30.4 23.2 44.4 66.7 27.5 13.2 21.6 23.3 42.0 20.6 19.0 35.0 39.7 22.0 20.5 28.6 46.9 49.0 51.5 45.2 51.7 43.5 48.5 39.0 43.9 57.6 48.9 37.1 45.7 21.6 46.4 54.1 61.3 47.4 64.6 39.4 37.7 18.6 33.5 35.0 27.7 41.4 27.6 30.7 33.6 POLR2H RPB8 ENSG00000163882 "RNA polymerase II subunit H" P52434 3 184361718-184368596 "Predicted intracellular proteins, RNA polymerase related proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037745, HPA055813" Supported Supported Nucleoplasm Nucleoplasm "HPA037745: AB_10672914, HPA055813: " "unprognostic (3.21e-1)" "unprognostic (4.96e-3)" "unprognostic (3.61e-3)" "unprognostic (7.15e-2)" "unprognostic (1.17e-2)" "unprognostic (6.72e-2)" "prognostic unfavourable (2.01e-4)" "unprognostic (8.82e-3)" "unprognostic (2.84e-1)" "unprognostic (4.02e-3)" "unprognostic (4.24e-2)" "unprognostic (1.27e-3)" "prognostic unfavourable (1.65e-10)" "unprognostic (1.34e-1)" "unprognostic (4.01e-1)" "unprognostic (1.71e-1)" "unprognostic (2.93e-3)" 18.1 32.6 19.6 19.2 17.5 14.8 24.5 24.2 24.6 28.8 29.9 13.8 19.8 32.0 19.9 23.5 26.7 23.1 26.7 16.3 17.8 16.3 34.1 41.0 17.8 21.7 16.4 17.0 21.8 46.4 15.8 20.7 27.2 17.0 19.2 33.6 19.7 26.0 17.0 19.9 20.7 38.8 20.0 13.2 21.5 25.6 20.6 12.5 28.1 29.7 23.1 26.3 18.5 16.2 17.4 18.2 7.7 15.3 14.6 26.6 11.5 50.1 17.7 19.1 28.2 21.3 15.2 23.7 19.0 19.9 26.0 33.5 45.2 24.1 28.4 47.6 14.8 20.4 34.0 34.1 23.3 27.8 45.0 27.3 20.8 28.2 19.2 28.7 16.0 19.5 19.5 17.0 30.7 26.9 21.0 18.9 20.6 59.6 28.3 38.4 20.7 36.9 16.6 17.5 38.5 31.0 22.8 28.9 20.5 16.0 49.8 27.6 62.2 23.1 14.0 12.4 19.6 16.5 50.5 38.0 39.4 53.2 19.7 30.7 16.5 3.4 9.6 7.7 15.2 15.3 18.4 17.4 18.0 16.2 18.0 16.4 26.6 19.7 0.7 14.6 9.6 18.2 18.7 11.5 19.6 17.5 24.2 24.6 17.8 16.3 16.4 17.0 17.0 12.5 POLR2I "hRPB14.5, RPB9" ENSG00000105258 "RNA polymerase II subunit I" P36954 19 36113710-36115346 "Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035632, HPA045156" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA035632: , HPA045156: AB_10964748" "unprognostic (1.95e-2)" "unprognostic (7.88e-3)" "unprognostic (3.54e-1)" "unprognostic (7.41e-3)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (1.24e-2)" "unprognostic (4.12e-2)" "unprognostic (7.39e-2)" "unprognostic (4.69e-3)" "unprognostic (2.86e-2)" "unprognostic (8.16e-2)" "unprognostic (1.83e-1)" "unprognostic (3.36e-2)" "unprognostic (3.84e-3)" "unprognostic (1.08e-1)" "unprognostic (1.16e-1)" 9.6 10.7 27.4 6.1 26.7 10.7 14.3 17.5 29.3 15.1 12.4 24.5 9.8 12.4 9.2 10.7 11.5 18.2 10.4 21.6 25.8 23.7 10.7 19.8 8.6 10.1 29.0 17.1 14.0 25.9 9.7 14.0 8.3 16.2 10.9 6.6 7.4 18.4 18.5 30.3 14.8 7.1 9.4 37.8 10.3 11.4 26.8 16.6 9.7 11.4 15.9 9.3 8.3 7.9 13.5 22.0 6.9 10.2 9.2 13.7 10.3 7.5 23.8 4.0 4.2 2.9 2.5 9.0 6.8 3.6 9.6 5.4 14.8 5.4 16.1 14.0 2.4 4.9 6.7 9.8 2.0 14.7 25.0 18.4 7.0 11.2 6.8 15.5 7.9 3.6 5.5 5.5 5.6 4.2 11.5 7.1 3.0 21.4 8.1 16.5 9.3 20.6 14.7 5.9 10.5 7.7 4.6 26.0 14.8 7.9 14.1 4.0 6.7 5.2 4.2 6.4 11.1 4.2 9.1 6.8 13.1 11.3 8.7 10.0 6.9 6.9 10.2 5.9 9.0 7.2 11.8 13.5 11.2 12.3 13.2 13.3 13.7 12.7 0.6 9.2 8.7 22.0 10.7 10.3 27.4 26.7 17.5 29.1 25.8 23.7 29.0 17.1 16.2 16.6 POLR2J "hRPB14, POLR2J1, RPB11, RPB11A, RPB11m" ENSG00000005075 "RNA polymerase II subunit J" P52435 7 102473118-102478907 "Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046970 Approved Nucleoplasm Nucleoplasm "HPA046970: " "unprognostic (1.11e-1)" "unprognostic (1.24e-2)" "unprognostic (1.46e-2)" "unprognostic (1.62e-1)" "unprognostic (1.90e-2)" "unprognostic (4.80e-2)" "unprognostic (6.47e-2)" "unprognostic (4.26e-2)" "unprognostic (3.46e-1)" "unprognostic (1.53e-3)" "unprognostic (4.46e-2)" "unprognostic (7.32e-2)" "unprognostic (7.13e-2)" "unprognostic (2.45e-1)" "unprognostic (4.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" 19.0 28.1 30.9 16.5 28.9 37.0 52.2 17.9 27.6 20.0 20.6 15.1 22.7 22.2 16.3 27.9 20.0 19.6 27.9 65.7 26.1 25.1 21.0 40.9 21.2 31.9 28.5 17.8 21.7 50.2 16.0 23.4 15.6 22.3 18.4 16.7 19.4 28.2 23.9 75.9 19.1 24.3 28.1 35.9 18.6 20.7 18.1 23.1 20.8 24.9 38.8 18.6 19.9 18.3 42.8 42.3 63.4 40.1 25.5 44.8 38.1 30.9 31.7 21.8 28.6 20.7 16.0 16.0 17.2 18.5 25.3 21.6 28.8 24.2 14.4 33.3 24.0 16.7 20.1 21.2 15.6 26.7 35.9 14.3 22.8 27.8 25.3 27.7 21.6 20.8 26.6 22.7 12.8 22.6 33.5 42.9 20.7 95.6 45.4 49.5 20.2 40.9 21.7 21.4 42.2 20.2 20.7 18.5 30.9 20.8 39.7 24.5 17.8 34.0 18.2 28.7 36.6 44.9 33.6 26.5 38.5 37.1 25.5 34.5 33.3 48.3 40.1 63.4 32.1 39.1 30.4 42.8 34.5 35.6 31.3 37.6 29.8 30.0 58.5 25.5 35.5 42.3 44.8 38.1 30.9 28.9 17.9 27.6 26.1 25.1 28.5 17.8 22.3 23.1 POLR2K RPB10alpha ENSG00000147669 "RNA polymerase II subunit K" P53803 8 100150584-100154002 "Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047477 Approved "Nucleoplasm,Nucleoli fibrillar center,Intermediate filaments" "Nucleoplasm, Nucleoli fibrillar center" "Intermediate filaments" "HPA047477: " "unprognostic (3.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-3)" "unprognostic (2.75e-2)" "unprognostic (4.68e-2)" "unprognostic (1.58e-2)" "unprognostic (1.62e-1)" "unprognostic (2.45e-1)" "unprognostic (1.57e-2)" "unprognostic (9.75e-3)" "unprognostic (5.73e-2)" "unprognostic (5.65e-2)" "unprognostic (3.46e-2)" "unprognostic (3.07e-2)" "unprognostic (9.16e-2)" "unprognostic (3.43e-2)" 31.4 43.7 51.1 22.0 38.7 32.9 41.5 34.7 53.0 33.8 28.5 24.7 20.8 21.2 29.3 42.7 33.1 23.8 23.9 35.3 46.2 51.0 47.5 46.6 27.3 29.7 49.0 35.0 26.2 20.2 28.2 36.8 27.1 46.0 37.8 31.8 21.5 32.7 33.3 23.3 21.8 28.4 34.8 40.4 31.9 26.6 22.6 23.7 24.9 36.6 22.3 31.5 39.3 23.1 29.0 30.0 24.2 19.2 25.0 30.9 24.2 39.3 19.9 25.7 18.1 27.7 25.3 17.4 29.2 24.1 29.8 36.3 12.3 27.1 26.4 58.0 23.1 18.1 27.6 24.1 39.5 42.0 30.6 35.8 25.1 25.9 22.0 23.1 26.1 20.5 32.2 23.7 24.3 27.0 28.0 25.9 29.1 25.0 58.4 34.3 26.8 39.6 23.0 14.9 38.1 37.1 22.2 54.3 35.7 19.8 17.8 42.3 36.3 35.3 20.4 17.6 25.3 27.2 31.0 26.7 42.2 41.5 33.4 40.7 27.4 24.2 15.2 22.1 23.7 19.2 28.2 29.0 30.9 29.4 19.0 19.7 27.1 29.3 5.8 25.0 18.2 30.0 30.9 24.2 51.1 38.7 34.7 53.0 46.2 51.0 49.0 35.0 46.0 23.7 POLR2L "hRPB7.6, hsRPB10b, RBP10, RPABC5, RPB10beta, RPB7.6" ENSG00000177700 "RNA polymerase II subunit L" P62875 11 837356-842545 "Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 85.8;PC-3: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.65e-2)" "unprognostic (6.56e-3)" "unprognostic (1.40e-1)" "unprognostic (5.71e-2)" "unprognostic (3.49e-2)" "unprognostic (3.46e-2)" "prognostic unfavourable (2.37e-4)" "unprognostic (6.17e-3)" "unprognostic (1.34e-1)" "unprognostic (7.51e-3)" "unprognostic (2.37e-2)" "unprognostic (6.77e-2)" "prognostic favourable (5.56e-4)" "unprognostic (3.60e-2)" "unprognostic (1.32e-1)" "unprognostic (4.03e-3)" "unprognostic (1.73e-1)" 42.9 27.7 22.4 18.4 18.3 16.9 63.3 10.1 18.8 16.6 28.3 9.9 29.7 18.7 14.1 23.8 37.5 15.0 28.5 86.7 19.2 17.3 32.9 43.3 26.3 21.2 18.8 10.7 16.6 88.3 14.8 21.1 21.0 12.5 19.3 11.5 23.0 41.6 35.4 44.8 17.3 18.9 21.5 13.5 19.2 17.1 18.3 9.3 18.7 37.9 41.8 15.7 17.6 21.0 28.6 52.3 43.0 44.1 41.7 38.6 42.2 15.7 85.8 8.1 10.0 23.4 17.1 7.3 20.3 14.2 20.0 13.4 25.0 14.7 9.9 5.6 25.2 10.6 12.1 24.3 6.3 9.1 59.1 9.4 25.5 31.6 13.9 9.0 7.7 28.0 11.0 11.4 5.7 15.8 9.9 11.0 23.6 39.6 9.1 9.5 12.7 109.9 8.9 6.5 15.1 24.2 12.1 16.4 5.2 20.2 20.7 15.5 12.4 5.4 17.6 13.6 10.7 7.4 12.5 6.7 7.6 9.6 20.6 8.9 11.9 26.4 44.1 43.0 36.1 38.4 38.6 28.6 34.4 35.7 41.7 26.0 29.5 35.6 11.5 41.7 25.9 52.3 33.0 42.2 22.4 18.3 10.1 18.8 19.2 17.3 18.8 10.7 12.5 9.3 POLR3A "hRPC155, RPC1, RPC155" ENSG00000148606 "RNA polymerase III subunit A" O14802 10 77969251-78029545 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037926 Uncertain Supported Nucleoplasm Nucleoplasm "HPA037926: AB_10672400" "unprognostic (6.83e-2)" "unprognostic (3.41e-2)" "unprognostic (4.54e-2)" "unprognostic (2.76e-2)" "unprognostic (6.41e-2)" "unprognostic (1.75e-1)" "prognostic unfavourable (3.64e-6)" "unprognostic (3.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (6.64e-2)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (1.34e-1)" "unprognostic (3.19e-1)" "unprognostic (1.30e-1)" "unprognostic (4.11e-2)" 7.1 10.2 10.3 8.3 21.7 5.9 10.6 22.2 29.7 9.2 8.1 12.8 7.4 8.6 9.4 13.3 8.6 8.5 7.4 7.4 9.4 9.6 9.3 9.3 6.8 8.7 8.1 11.0 11.5 10.7 13.8 17.3 10.1 20.4 10.2 10.7 10.4 8.6 8.2 17.6 11.2 7.8 9.7 6.6 8.9 8.2 11.7 9.8 12.6 9.6 4.4 13.4 7.9 8.0 7.5 5.4 8.0 6.4 6.5 8.8 3.6 7.3 8.8 9.3 15.4 6.1 7.9 6.2 8.4 11.0 10.9 10.8 11.5 5.3 9.1 5.2 7.3 8.6 16.1 9.2 13.3 6.7 11.8 7.3 7.0 14.2 5.8 12.5 6.2 6.7 6.6 19.3 18.0 9.5 13.6 5.7 10.5 5.4 9.4 8.0 10.1 40.0 9.0 5.9 5.9 5.4 4.8 8.5 10.8 8.1 15.1 8.6 11.2 6.6 10.4 7.0 6.8 7.6 16.6 8.9 9.3 11.1 12.5 13.2 3.4 8.0 5.2 2.9 7.8 6.4 7.6 5.6 6.0 7.2 4.8 7.5 5.7 6.6 3.3 6.5 5.4 5.4 8.8 3.6 10.3 21.7 22.2 29.7 9.4 9.6 8.1 11.0 20.4 9.8 POLR3B "FLJ10388, RPC2" ENSG00000013503 "RNA polymerase III subunit B" Q9NW08 12 106357658-106510198 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036466 Supported Approved "Nuclear speckles" "Nuclear speckles" "HPA036466: AB_10671842" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (4.80e-2)" "unprognostic (1.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-1)" "unprognostic (4.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.33e-1)" "unprognostic (3.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.09e-2)" "prognostic favourable (1.21e-4)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" 6.4 14.0 7.1 7.9 14.6 6.5 6.9 8.6 13.6 8.6 7.2 8.2 5.7 6.0 10.1 7.2 14.8 7.7 5.8 8.2 8.9 7.1 9.9 17.5 7.1 11.4 6.2 10.4 11.3 11.9 22.5 17.0 22.9 12.3 8.0 8.3 6.2 8.6 9.9 12.1 15.3 5.7 7.8 6.0 6.4 7.5 9.9 4.7 10.3 8.5 10.2 10.0 7.3 10.1 4.3 4.9 9.8 4.1 3.7 6.3 3.1 11.1 5.3 11.8 5.6 10.5 9.6 16.4 15.7 9.5 10.9 8.5 9.7 3.1 14.2 5.6 9.7 10.4 13.6 13.4 13.6 11.5 9.1 11.3 7.1 8.2 6.7 17.9 12.3 8.5 9.6 10.9 12.7 8.1 16.6 4.7 8.3 8.2 13.0 6.0 12.7 19.9 7.9 7.0 9.3 6.2 15.2 12.8 7.0 9.6 12.9 9.2 12.0 5.3 7.7 6.0 7.1 9.7 9.0 5.8 14.8 21.2 2.9 11.1 6.4 9.8 3.9 2.6 4.1 4.1 5.5 4.3 4.5 4.3 4.9 2.6 6.3 3.9 2.6 3.7 4.0 1.8 4.7 3.1 7.1 14.6 8.6 13.6 8.9 7.1 6.2 10.4 12.3 4.7 POLR3C "RPC3, RPC62" ENSG00000186141 "RNA polymerase III subunit C" Q9BUI4 1 145824088-145842505 "Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027508, HPA027516" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA027508: AB_10600091, HPA027516: AB_10600894" "unprognostic (1.43e-2)" "unprognostic (1.70e-2)" "unprognostic (2.97e-2)" "prognostic unfavourable (1.56e-4)" "unprognostic (6.87e-2)" "unprognostic (1.73e-1)" "prognostic unfavourable (5.48e-4)" "unprognostic (2.51e-1)" "prognostic unfavourable (1.50e-4)" "unprognostic (1.13e-1)" "unprognostic (1.41e-2)" "unprognostic (4.46e-1)" "prognostic unfavourable (1.85e-5)" "unprognostic (2.34e-1)" "unprognostic (4.95e-2)" "unprognostic (1.07e-2)" "unprognostic (1.38e-1)" 21.1 11.9 13.5 21.2 13.4 16.9 21.7 28.3 16.4 18.0 14.2 12.2 11.1 9.4 19.2 16.2 15.1 16.9 14.6 12.7 12.1 9.9 15.7 15.3 13.3 25.4 14.7 15.8 21.9 23.1 16.7 10.9 13.9 12.6 15.7 15.9 11.9 16.9 13.0 18.3 20.3 14.9 17.5 11.0 20.5 14.9 29.3 15.0 26.5 15.9 11.4 21.3 17.5 15.8 21.1 23.6 29.5 23.9 20.6 20.7 15.9 15.8 13.2 11.0 9.1 14.5 17.7 11.7 15.0 18.5 21.5 20.6 19.0 8.6 27.4 15.3 20.5 15.8 17.8 16.1 22.3 11.2 14.0 14.6 15.4 11.3 26.2 30.1 19.0 16.9 11.8 24.0 42.8 13.3 18.4 16.2 22.6 22.1 15.6 13.7 15.7 17.7 14.6 13.7 18.0 14.0 11.4 10.2 15.4 13.5 19.8 20.3 15.2 28.2 13.9 18.9 15.0 10.3 21.0 25.4 24.6 31.9 6.9 15.6 14.5 29.5 20.9 21.1 15.9 23.9 20.7 20.1 17.6 16.4 22.0 21.1 18.0 16.4 1.7 20.6 17.3 23.6 14.9 15.9 13.5 13.4 28.3 16.4 12.1 9.9 14.7 15.8 12.6 15.0 POLR3D "BN51T, RPC4, TSBN51" ENSG00000168495 "RNA polymerase III subunit D" P05423 8 22245104-22254600 "Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061331, HPA067875, HPA068461, HPA069089" Supported Enhanced Nucleoplasm Nucleoplasm "HPA061331: , HPA067875: , HPA068461: , HPA069089: " "unprognostic (2.33e-1)" "unprognostic (2.27e-1)" "unprognostic (9.38e-3)" "unprognostic (9.33e-3)" "unprognostic (1.24e-1)" "unprognostic (8.02e-2)" "prognostic unfavourable (1.21e-4)" "unprognostic (2.02e-1)" "unprognostic (2.19e-2)" "unprognostic (3.27e-1)" "unprognostic (8.03e-2)" "unprognostic (2.20e-1)" "prognostic unfavourable (9.15e-6)" "unprognostic (1.15e-1)" "unprognostic (3.13e-1)" "unprognostic (6.93e-2)" "prognostic unfavourable (2.12e-4)" 14.7 12.9 10.3 14.0 13.6 9.8 18.4 8.8 15.7 13.9 11.9 13.9 8.2 9.3 14.3 9.3 16.5 11.9 13.9 16.6 10.0 8.3 11.7 11.2 12.7 13.4 16.5 13.7 18.1 20.8 10.5 16.3 20.2 13.2 14.5 11.9 9.7 14.5 11.2 34.4 11.9 9.6 17.5 13.5 13.2 12.2 29.4 12.0 8.0 12.6 10.8 13.1 14.7 15.9 9.1 13.6 1.6 5.7 11.2 10.7 5.3 6.5 19.7 10.8 12.2 10.6 15.5 11.7 17.8 11.0 15.3 13.1 14.0 5.5 21.7 15.2 11.3 11.5 24.6 8.3 12.3 7.1 9.3 19.0 10.0 19.0 16.8 5.9 14.9 12.8 16.7 19.3 22.5 12.8 25.0 14.3 12.4 9.9 21.6 12.5 27.2 11.3 17.0 14.4 16.6 7.2 5.9 12.4 22.9 7.1 8.2 24.7 6.4 8.3 14.0 14.9 14.0 18.5 17.5 16.5 15.1 13.4 10.0 10.9 19.6 0.1 5.6 1.6 8.5 5.6 10.4 8.3 9.1 10.3 7.4 9.1 10.7 9.4 0.2 11.2 5.7 13.6 5.9 5.3 10.3 13.6 8.8 15.7 10.0 8.3 16.5 13.7 13.2 12.0 POLR3E "FLJ10509, RPC5, SIN" ENSG00000058600 "RNA polymerase III subunit E" Q9NVU0 16 22297375-22335103 "Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041419, HPA041477" Approved Enhanced Nucleoplasm Nucleoplasm "HPA041419: AB_2677468, HPA041477: AB_10796345" "unprognostic (3.09e-2)" "unprognostic (8.59e-2)" "unprognostic (8.23e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-1)" "unprognostic (7.28e-2)" "unprognostic (2.42e-2)" "unprognostic (7.73e-2)" "unprognostic (2.96e-2)" "unprognostic (1.34e-1)" "unprognostic (2.03e-1)" "prognostic unfavourable (1.74e-4)" "unprognostic (8.14e-2)" "unprognostic (1.91e-1)" "unprognostic (8.96e-2)" "unprognostic (8.19e-3)" "unprognostic (3.41e-2)" 10.8 15.8 8.9 10.4 11.1 9.8 15.5 11.7 12.9 11.7 10.7 12.0 13.0 9.7 12.4 9.3 13.1 11.1 8.5 13.9 10.9 7.0 9.5 14.0 9.5 12.7 11.1 9.8 11.0 21.2 15.7 15.8 8.9 10.7 12.7 6.6 11.8 15.0 15.2 50.7 12.7 8.9 9.2 10.0 9.5 12.4 9.6 10.7 10.4 12.3 9.1 14.0 11.4 10.4 5.9 5.7 1.9 3.8 5.3 7.2 4.8 6.6 9.2 2.7 6.7 5.2 4.0 9.1 5.3 2.7 3.5 2.5 11.6 4.7 13.7 7.0 3.7 6.4 13.2 7.4 2.9 9.1 18.9 7.0 10.1 22.2 6.5 10.9 7.7 3.9 8.3 7.6 9.3 9.1 19.8 5.6 4.1 10.7 10.9 4.5 13.6 7.8 14.2 6.0 17.6 3.7 3.9 9.8 7.3 5.1 9.4 5.2 5.4 6.3 5.7 3.6 4.1 3.1 5.8 7.6 13.5 12.6 4.1 8.3 6.7 0.0 3.3 1.9 6.5 3.8 7.2 5.9 7.2 6.8 5.7 5.1 7.0 5.8 0.3 5.3 3.1 3.3 7.2 4.8 8.9 11.1 11.7 12.9 10.9 7.0 11.1 9.8 10.7 10.7 POLR3F "RPC39, RPC6" ENSG00000132664 "RNA polymerase III subunit F" Q9H1D9 20 18467127-18484643 "Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049441, HPA050173, HPA072298" Uncertain Approved Nucleoplasm Nucleoplasm "HPA049441: AB_2680768, HPA050173: , HPA072298: " "unprognostic (4.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.55e-1)" "unprognostic (7.39e-2)" "prognostic unfavourable (8.87e-9)" "unprognostic (1.80e-1)" "unprognostic (1.50e-1)" "unprognostic (2.20e-1)" "prognostic favourable (6.48e-4)" "unprognostic (3.04e-1)" "unprognostic (4.01e-1)" "unprognostic (3.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.88e-3)" "unprognostic (4.98e-3)" 8.6 7.8 8.1 6.0 11.9 4.4 8.0 24.6 15.3 9.9 7.5 8.7 8.5 5.6 11.6 6.5 11.0 9.6 6.7 14.2 8.7 10.1 11.2 7.3 5.9 8.8 7.8 12.9 12.5 7.3 4.5 9.8 8.0 13.9 9.2 6.4 6.7 7.5 7.4 12.0 6.2 5.0 9.0 8.5 6.3 6.7 10.0 7.7 6.3 16.3 7.2 9.1 10.7 6.5 3.1 3.2 1.9 4.5 3.3 6.4 4.1 6.4 6.6 6.9 8.6 5.6 6.8 12.4 9.6 6.7 12.3 9.4 8.2 6.6 5.0 4.0 9.2 8.9 9.1 7.9 8.1 5.0 7.6 3.6 2.5 3.6 8.0 10.8 6.2 4.3 5.1 18.4 8.4 5.5 9.3 4.4 8.4 7.0 9.0 4.6 9.7 15.0 6.4 15.0 5.5 5.5 2.8 14.4 9.5 7.3 12.4 15.4 5.7 7.3 5.3 12.7 6.2 9.4 13.3 2.3 15.1 4.0 5.3 5.0 9.1 0.1 2.1 1.9 4.3 4.5 6.4 2.8 3.9 1.2 2.2 3.1 4.1 2.1 0.8 3.3 1.9 3.2 3.4 4.1 8.1 11.9 24.6 15.3 8.7 10.1 7.8 12.9 13.9 7.7 POLR3G "RPC32, RPC7" ENSG00000113356 "RNA polymerase III subunit G" O15318 5 90471748-90514553 "Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.2" "Cell line enhanced" "Detected in all" "WM-115: 36.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010109, HPA052658" Enhanced Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB010109: AB_2165718, HPA052658: " "unprognostic (4.31e-1)" "unprognostic (5.35e-2)" "unprognostic (2.62e-2)" "unprognostic (3.55e-3)" "unprognostic (1.18e-1)" "unprognostic (3.42e-2)" "unprognostic (4.19e-6)" "unprognostic (2.17e-3)" "unprognostic (1.91e-1)" "unprognostic (1.93e-2)" "unprognostic (3.52e-2)" "unprognostic (9.71e-2)" "unprognostic (1.21e-14)" "unprognostic (3.86e-2)" "unprognostic (3.19e-2)" "unprognostic (1.53e-2)" "unprognostic (8.17e-5)" 2.7 1.6 7.1 3.6 10.2 4.4 3.8 7.2 7.2 3.7 2.6 6.7 1.4 2.8 2.7 8.4 7.3 2.7 2.4 2.7 7.7 7.7 1.7 4.0 2.9 8.1 10.3 6.1 4.1 4.1 11.1 3.9 3.1 20.2 2.9 3.1 2.6 4.2 1.5 4.4 7.4 2.3 4.2 16.0 3.3 2.1 8.0 8.1 1.0 5.9 8.5 3.2 4.4 4.7 3.9 2.1 6.8 2.8 5.4 3.2 0.8 10.5 6.1 7.2 1.9 2.2 4.1 3.3 5.3 1.7 8.4 6.9 3.5 7.9 29.0 1.8 2.2 4.4 9.0 8.5 30.3 13.3 8.1 10.6 2.9 5.4 3.8 7.4 2.7 2.7 3.9 14.1 10.7 10.4 15.1 2.6 3.0 5.2 7.7 4.7 34.4 27.3 6.9 3.2 16.3 2.5 1.0 9.2 2.5 2.1 4.0 14.6 2.2 2.1 12.4 4.6 8.9 6.5 19.9 6.6 17.2 21.3 10.2 9.9 36.7 6.8 0.6 0.3 3.2 0.8 1.6 3.9 1.1 2.0 0.9 2.4 2.4 2.6 1.6 5.4 2.8 2.1 0.5 0.8 7.1 10.2 7.2 7.2 7.7 7.7 10.3 6.1 20.2 8.1 POLR3GL "flj32422, MGC3200" ENSG00000121851 "RNA polymerase III subunit G like" Q9BT43 1 145964702-145978848 "Predicted intracellular proteins, RNA polymerase related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA027288 Uncertain "HPA027288: AB_10602119" "prognostic favourable (2.96e-4)" "unprognostic (3.58e-3)" "unprognostic (1.55e-2)" "prognostic favourable (6.52e-5)" "unprognostic (2.88e-1)" "unprognostic (1.19e-1)" "unprognostic (2.23e-1)" "unprognostic (1.37e-2)" "unprognostic (4.15e-2)" "unprognostic (2.11e-1)" "unprognostic (5.98e-3)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (9.96e-2)" "unprognostic (3.61e-1)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" 30.4 23.9 20.7 18.9 21.4 16.6 21.2 16.0 17.2 17.8 21.9 18.4 14.8 13.3 18.0 19.8 17.7 15.5 29.4 47.4 18.0 15.5 16.6 36.6 18.0 23.9 20.7 17.1 22.0 11.5 26.0 20.7 13.3 14.5 18.7 17.4 20.8 14.6 17.8 66.3 14.1 18.7 16.8 18.1 25.2 19.3 10.7 20.9 26.6 25.2 22.9 26.8 20.2 23.5 28.5 13.4 61.6 17.3 25.7 41.7 22.7 10.0 4.5 10.5 9.6 26.6 30.0 2.5 10.1 16.0 6.9 10.6 1.4 11.2 21.6 15.3 14.2 3.1 5.1 10.0 10.7 23.3 5.6 14.3 3.7 7.0 16.4 14.3 20.4 22.6 6.7 11.5 13.4 18.3 23.8 18.9 26.7 10.7 11.6 18.1 2.2 10.0 9.8 13.0 32.5 11.2 2.3 5.7 10.7 14.4 0.9 20.2 9.0 23.2 18.9 6.6 4.3 12.8 6.8 30.9 9.4 16.8 11.9 17.3 5.9 46.8 13.2 61.6 32.0 17.1 30.5 28.5 32.7 31.4 13.4 26.9 33.5 34.4 10.2 25.7 17.3 10.5 41.7 22.7 20.7 21.4 16.0 17.2 18.0 15.5 20.7 17.1 14.5 20.9 POLR3H "KIAA1665, RPC8" ENSG00000100413 "RNA polymerase III subunit H" Q9Y535 22 41525804-41544606 "Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046787 Approved Supported Nucleoplasm,Vesicles,Centrosome Nucleoplasm "Vesicles, Centrosome" "HPA046787: AB_2679806" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (9.57e-2)" "unprognostic (1.26e-1)" "prognostic unfavourable (2.04e-4)" "unprognostic (2.05e-2)" "unprognostic (1.33e-2)" "unprognostic (5.43e-2)" "prognostic favourable (5.41e-4)" "unprognostic (6.40e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-2)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (1.70e-1)" 16.8 14.0 30.0 9.1 28.8 5.5 13.5 21.0 27.4 12.1 7.5 15.8 12.6 6.1 10.5 11.7 17.0 19.0 10.3 14.8 24.0 20.5 10.0 18.9 14.7 10.9 22.2 17.6 22.4 13.7 13.1 11.5 7.9 17.2 11.0 6.8 12.1 12.2 14.2 7.7 14.6 6.2 14.4 14.2 7.2 7.9 14.2 16.5 7.0 15.4 8.2 9.3 8.1 9.1 11.6 11.2 0.6 13.8 3.9 10.2 7.5 16.1 10.9 10.1 14.7 11.1 10.1 6.7 13.6 12.7 23.2 18.7 22.0 5.3 13.8 10.7 22.8 7.4 18.5 22.2 14.6 12.5 22.8 8.2 17.3 10.5 11.5 34.1 14.1 12.6 14.5 30.5 8.2 11.3 17.3 8.9 12.9 15.4 8.7 9.3 7.1 14.2 13.4 7.9 14.3 10.8 9.5 9.8 5.8 17.7 18.0 8.6 7.2 9.7 10.1 13.9 15.0 24.0 18.0 6.7 12.5 20.8 24.2 12.2 13.1 0.0 10.0 0.1 7.3 13.8 10.2 11.6 7.1 8.6 11.2 10.1 10.0 8.1 0.6 3.9 12.7 10.8 4.4 7.5 30.0 28.8 21.0 26.9 24.0 20.5 22.2 17.6 17.2 16.5 POLR3K RPC11 ENSG00000161980 "RNA polymerase III subunit K" Q9Y2Y1 16 46407-53628 "Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA005891 Approved Uncertain Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA005891: AB_1079653" "unprognostic (3.00e-1)" "unprognostic (1.50e-3)" "unprognostic (1.53e-1)" "unprognostic (7.16e-3)" "unprognostic (1.47e-1)" "unprognostic (1.40e-1)" "unprognostic (8.03e-3)" "unprognostic (9.06e-2)" "unprognostic (7.40e-2)" "unprognostic (5.72e-2)" "unprognostic (9.96e-2)" "unprognostic (1.84e-1)" "unprognostic (7.36e-3)" "unprognostic (2.68e-2)" "unprognostic (3.63e-2)" "unprognostic (3.53e-2)" "unprognostic (9.63e-2)" 7.3 12.4 15.4 16.6 17.6 11.3 8.3 14.3 18.8 8.0 9.1 9.0 11.9 9.8 8.3 9.3 9.8 9.3 7.4 12.0 13.7 15.4 9.1 10.3 7.6 19.6 11.9 15.5 9.1 11.0 12.1 7.5 8.0 9.0 10.0 9.2 5.9 11.1 12.7 21.8 5.7 9.3 8.2 9.8 14.0 9.1 5.7 7.9 13.7 11.5 12.4 18.6 9.9 8.6 39.6 25.3 32.2 18.9 13.5 30.0 18.2 10.7 18.5 11.8 12.2 4.9 2.9 9.4 15.3 4.9 13.7 9.0 23.8 11.6 27.9 11.7 5.4 10.7 27.4 7.1 9.8 16.7 25.2 20.5 13.9 16.9 3.7 18.4 20.2 2.9 6.2 15.1 7.7 6.7 29.1 8.9 8.8 26.7 22.1 12.2 19.3 17.7 26.9 13.6 29.1 7.7 7.7 17.3 10.2 10.5 19.7 9.0 11.6 16.7 6.3 8.8 10.8 11.8 18.5 5.7 13.7 54.9 3.8 13.5 13.1 9.0 13.6 32.2 15.8 18.9 16.2 39.6 20.3 18.2 12.4 35.1 18.4 17.2 9.8 13.5 17.3 25.3 30.0 18.2 15.4 17.6 14.3 18.8 13.7 15.4 11.9 15.5 9.0 7.9 POLRMT "APOLMT, h-mtRPOL, MTRNAP, MTRPOL" ENSG00000099821 "RNA polymerase mitochondrial" O00411 19 617224-633604 "Enzymes, Predicted intracellular proteins" Transcription "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006366 Uncertain Supported Mitochondria Mitochondria "HPA006366: AB_1079654" "unprognostic (3.24e-1)" "unprognostic (4.31e-2)" "unprognostic (7.96e-2)" "prognostic favourable (4.50e-4)" "unprognostic (9.46e-2)" "unprognostic (2.94e-2)" "unprognostic (3.04e-2)" "unprognostic (9.41e-2)" "unprognostic (1.45e-1)" "unprognostic (3.48e-1)" "unprognostic (7.64e-3)" "unprognostic (1.81e-2)" "unprognostic (1.62e-1)" "unprognostic (1.28e-3)" "unprognostic (1.66e-1)" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" 10.2 10.7 10.1 16.3 11.9 6.9 8.1 12.1 20.7 9.5 11.6 12.3 4.4 16.7 9.8 12.2 14.4 8.7 12.7 24.7 11.5 8.9 12.9 21.4 7.3 11.8 9.4 15.1 10.1 15.9 9.5 10.7 6.2 9.7 10.2 8.8 8.5 9.6 11.7 42.2 16.7 12.8 10.8 8.4 12.8 11.2 32.1 6.3 11.6 11.1 8.6 10.4 10.1 7.8 8.2 7.3 3.1 5.5 7.5 9.0 5.3 10.4 19.0 4.3 19.1 9.1 5.2 16.0 4.9 5.8 7.3 6.7 19.1 7.2 10.8 10.0 4.5 10.9 16.1 9.4 5.4 12.1 38.3 8.4 11.8 24.5 9.5 14.1 16.0 5.0 13.3 7.4 9.1 10.3 15.7 10.8 6.7 14.8 18.7 19.4 17.3 13.4 18.1 6.0 18.4 9.7 9.0 14.0 9.9 4.4 12.2 12.2 6.9 12.9 6.1 7.9 10.2 12.4 14.4 25.8 21.2 16.5 17.0 11.8 9.7 0.0 3.7 3.1 9.0 5.2 7.1 7.8 6.7 6.6 7.3 8.2 5.7 6.3 0.6 7.5 5.5 7.2 4.1 5.3 10.1 11.9 12.1 20.7 11.5 8.9 9.4 15.1 9.7 6.3 RAD1 "HRAD1, REC1" ENSG00000113456 "RAD1 checkpoint DNA exonuclease" O60671 5 34905264-34918989 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006692 Approved Supported Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA006692: " "prognostic unfavourable (6.30e-4)" "unprognostic (1.85e-2)" "unprognostic (9.40e-2)" "unprognostic (1.98e-3)" "unprognostic (2.00e-1)" "unprognostic (2.38e-2)" "prognostic unfavourable (1.06e-5)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.61e-3)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.11e-1)" "unprognostic (3.12e-3)" 3.1 6.5 3.4 3.2 4.9 4.8 4.4 5.2 4.7 5.4 3.2 2.9 4.6 3.8 3.7 3.5 3.3 6.6 3.5 4.4 3.7 3.5 5.6 6.1 2.9 4.0 3.3 3.0 3.4 6.0 5.3 3.1 4.3 3.7 7.4 4.5 3.6 3.3 2.6 3.1 3.7 5.8 5.2 4.7 3.8 4.7 9.4 7.6 7.2 3.1 4.8 9.3 2.6 5.8 6.8 7.2 14.0 5.1 5.9 10.4 9.2 9.0 9.7 8.0 6.4 8.0 15.2 3.3 8.2 5.4 7.9 5.6 10.9 6.8 6.8 8.1 20.7 4.3 8.7 11.1 7.5 5.3 4.8 10.5 7.0 4.6 14.4 9.0 8.2 7.2 11.3 7.9 9.4 10.3 10.4 15.2 5.3 4.7 6.2 7.5 7.9 19.0 13.0 8.5 8.0 9.3 4.2 12.7 9.6 6.5 9.6 5.0 9.1 13.4 6.6 16.8 8.8 7.2 3.0 6.8 5.9 3.1 7.7 8.7 6.5 8.0 2.9 9.4 9.3 8.0 2.3 4.8 2.9 7.6 5.3 2.6 RAD9A RAD9 ENSG00000172613 "RAD9 checkpoint clamp component A" Q99638 11 67317871-67398410 "Enzymes, Predicted intracellular proteins" "DNA damage" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006725, HPA048155" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA006725: AB_1856041, HPA048155: " "unprognostic (7.64e-2)" "prognostic favourable (6.95e-4)" "unprognostic (8.83e-3)" "unprognostic (1.13e-1)" "unprognostic (2.68e-1)" "unprognostic (2.12e-3)" "unprognostic (9.64e-3)" "unprognostic (1.05e-2)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (9.19e-2)" "unprognostic (2.50e-2)" "prognostic unfavourable (2.82e-5)" "unprognostic (6.16e-2)" "unprognostic (3.72e-3)" "unprognostic (2.19e-1)" "prognostic favourable (7.52e-6)" 5.4 5.2 7.0 10.6 8.4 10.8 6.1 7.7 6.3 6.7 11.8 8.5 5.1 14.2 7.1 4.1 8.2 12.1 6.3 6.1 3.8 3.5 6.9 9.4 9.5 9.0 7.8 2.5 6.8 20.1 3.7 7.2 10.2 5.5 8.6 3.3 4.9 12.8 8.1 7.8 12.8 17.5 5.5 4.1 10.7 11.3 7.2 6.0 18.2 11.7 7.2 16.8 6.2 7.1 6.7 5.1 8.9 3.9 4.7 9.0 3.2 6.7 11.0 5.8 8.3 1.7 0.8 7.8 4.3 2.9 5.0 4.3 13.1 12.9 8.1 8.1 0.9 11.4 3.4 3.3 0.7 7.7 9.5 10.9 5.9 6.5 2.4 7.1 14.4 2.1 3.4 4.3 1.8 3.3 8.8 9.0 1.0 20.9 13.8 13.8 8.8 8.3 11.5 7.9 9.2 1.3 5.4 6.7 7.2 6.0 16.5 13.6 11.6 6.8 2.5 7.2 9.4 14.6 5.1 9.6 8.9 7.1 4.8 7.0 5.9 8.0 3.2 8.9 9.0 3.6 6.4 6.7 7.2 7.3 2.1 5.3 4.9 5.7 4.7 4.7 3.9 5.1 3.9 3.2 7.0 8.4 7.7 6.3 3.8 3.5 7.8 2.5 5.5 6.0 REV3L "POLZ, REV3" ENSG00000009413 "REV3 like, DNA directed polymerase zeta catalytic subunit" O60673 6 111299028-111483715 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 39.4;ASC TERT1: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064853, HPA069382" Uncertain Approved Nucleoplasm Nucleoplasm "HPA064853: , HPA069382: " "unprognostic (5.54e-2)" "unprognostic (2.06e-1)" "unprognostic (5.09e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" "unprognostic (8.59e-3)" "unprognostic (4.42e-2)" "unprognostic (1.56e-2)" "unprognostic (8.09e-2)" "unprognostic (1.17e-1)" "unprognostic (6.87e-3)" "unprognostic (1.27e-1)" "unprognostic (4.34e-2)" "unprognostic (2.80e-1)" "unprognostic (1.67e-1)" "unprognostic (1.67e-1)" "unprognostic (1.03e-3)" 21.0 7.1 7.8 8.8 7.3 7.3 15.1 26.0 7.6 31.7 11.0 5.8 14.1 5.4 34.5 18.5 7.6 12.2 7.4 7.1 6.5 6.1 6.5 6.4 10.8 6.3 5.4 5.8 11.3 8.1 7.8 15.1 10.2 6.8 11.4 7.4 8.3 6.9 16.3 17.1 8.2 7.0 18.0 6.9 7.1 8.6 10.3 6.7 10.2 9.2 7.2 5.5 18.3 16.2 5.1 2.8 6.0 2.9 1.7 4.6 1.0 4.6 2.9 5.7 8.6 39.4 30.0 6.2 6.6 10.8 3.6 5.9 5.2 2.8 10.2 4.8 9.5 4.8 8.4 3.7 6.2 5.9 4.6 6.8 7.5 7.0 5.5 7.0 4.1 19.1 3.3 6.7 10.5 6.6 8.6 6.5 7.0 4.3 8.3 1.5 2.0 4.9 5.4 6.3 3.3 2.7 5.8 7.5 6.0 8.2 3.0 7.0 3.8 7.6 7.6 5.4 5.1 25.5 7.5 6.8 8.0 9.1 5.3 5.5 7.1 1.9 1.7 3.3 3.3 1.3 4.6 2.8 2.5 3.0 1.7 5.1 1.6 2.8 6.0 1.7 2.9 2.8 1.9 1.0 7.8 7.3 26.0 7.2 6.5 6.1 5.4 5.8 6.8 6.7 RFC5 RFC36 ENSG00000111445 "Replication factor C subunit 5" P40937 12 118013588-118033130 "Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041037 Supported Approved Nucleoplasm Nucleoplasm "HPA041037: AB_10805834" "unprognostic (9.63e-2)" "prognostic favourable (8.05e-5)" "unprognostic (5.12e-3)" "unprognostic (2.25e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-2)" "unprognostic (1.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.35e-3)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-2)" "prognostic unfavourable (2.30e-4)" "unprognostic (1.44e-1)" "unprognostic (2.15e-1)" "unprognostic (2.70e-1)" "unprognostic (5.06e-1)" 9.4 9.3 9.8 15.1 10.7 30.3 11.7 14.4 12.5 11.4 11.0 10.2 12.6 10.2 12.9 10.8 14.3 12.2 8.4 6.7 15.2 6.5 9.3 13.9 8.4 16.0 7.0 10.1 18.7 12.3 7.3 11.4 9.1 11.0 8.7 14.5 8.5 9.9 12.6 7.3 11.2 11.5 9.0 9.3 11.1 9.8 16.4 9.3 33.4 12.0 11.2 17.0 12.6 10.8 12.9 8.8 14.2 10.4 9.1 14.1 7.9 19.3 21.2 20.8 11.6 5.1 6.1 22.7 14.6 10.0 28.4 21.3 21.7 8.4 22.9 10.3 7.6 18.6 28.6 14.4 26.8 16.0 23.8 17.9 16.6 14.3 3.1 28.0 13.7 3.2 4.8 21.4 6.9 11.8 23.8 8.3 13.3 21.1 35.2 21.2 15.7 19.5 26.4 25.5 21.7 12.3 17.6 27.9 12.2 25.3 7.0 9.0 26.0 10.8 5.5 15.3 17.1 20.7 27.5 14.2 18.3 28.0 14.7 20.2 25.9 14.2 6.2 3.9 11.2 10.4 10.0 12.9 13.7 9.8 8.8 11.1 10.7 9.3 6.1 9.1 5.8 7.6 14.1 7.9 9.8 10.7 14.4 12.5 15.2 6.5 7.0 10.1 11.0 9.3 TK1 ENSG00000167900 "Thymidine kinase 1" P04183 17 78174075-78187233 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.8;lymphoid tissue: 41.8;tongue: 33.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-reg: 21.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB004683 Enhanced "CAB004683: AB_437067" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.14e-3)" "unprognostic (3.22e-1)" "unprognostic (1.94e-1)" "prognostic unfavourable (6.87e-4)" "prognostic unfavourable (3.03e-5)" "unprognostic (4.05e-2)" "unprognostic (3.18e-3)" "unprognostic (6.64e-3)" "unprognostic (2.76e-2)" "prognostic unfavourable (6.50e-11)" "unprognostic (5.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (4.94e-2)" 5.3 2.0 2.1 21.4 4.5 32.8 4.8 1.1 1.9 3.7 11.4 2.2 1.9 8.5 2.4 4.8 18.9 2.2 7.0 4.3 1.6 0.7 7.9 6.2 9.3 15.7 3.1 1.6 2.1 3.6 0.1 1.3 8.6 2.1 2.3 7.9 0.5 4.6 2.0 2.0 6.2 8.5 4.4 1.7 9.0 9.4 3.6 1.6 41.8 1.3 33.0 20.5 3.1 5.8 4.0 2.1 1.1 1.2 6.2 21.2 3.5 65.1 54.2 10.8 13.6 1.0 4.3 7.1 32.4 17.0 48.2 66.9 47.8 27.5 21.2 11.4 19.4 29.7 9.8 28.9 25.0 7.3 36.2 37.4 19.4 31.3 0.3 15.8 24.2 2.1 0.9 25.1 3.4 19.6 23.0 47.0 18.5 48.7 7.9 8.9 5.6 37.8 21.4 43.8 47.3 12.8 21.2 4.9 14.3 24.8 68.2 9.1 46.0 21.3 9.0 47.4 46.6 33.8 41.6 19.8 10.3 27.3 23.3 10.7 21.3 0.0 0.7 0.0 1.1 1.2 0.5 4.0 5.3 2.7 2.1 1.2 0.3 1.4 1.1 6.2 1.0 0.7 21.2 3.5 2.1 4.5 1.1 1.9 1.6 0.7 3.1 1.6 2.1 1.6 TK2 SCA31 ENSG00000166548 "Thymidine kinase 2, mitochondrial" O00142 16 66508003-66552544 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Disease mutation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041162 Uncertain "HPA041162: AB_10961178" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.27e-3)" "unprognostic (3.94e-1)" "unprognostic (2.93e-1)" "unprognostic (1.10e-1)" "unprognostic (4.83e-2)" "unprognostic (3.35e-2)" "unprognostic (3.45e-1)" "unprognostic (3.59e-2)" "unprognostic (2.85e-1)" "prognostic favourable (2.18e-6)" "unprognostic (3.05e-2)" "unprognostic (1.74e-1)" "unprognostic (2.71e-1)" "unprognostic (7.05e-2)" 34.0 25.4 18.5 9.0 18.9 6.2 25.5 13.1 22.4 19.8 10.9 17.2 18.5 9.5 15.2 29.0 11.0 17.4 18.3 15.2 19.2 15.5 20.9 27.8 16.5 11.5 18.2 18.5 23.7 21.6 50.2 18.0 12.9 27.9 14.9 11.5 13.7 18.1 18.8 20.8 10.0 10.5 17.0 28.2 17.4 12.0 29.4 15.5 6.5 23.4 9.0 8.7 15.5 18.6 1.4 12.6 10.3 15.6 4.4 4.3 3.3 4.7 9.4 5.1 5.3 28.1 23.1 0.3 8.2 10.0 6.6 7.7 2.8 10.5 0.1 9.1 25.6 4.1 2.5 6.8 4.3 3.1 2.3 0.8 6.0 5.2 20.0 1.3 3.6 17.2 6.5 7.6 10.5 9.8 2.8 11.1 15.5 1.6 2.5 6.2 2.5 5.6 2.8 9.2 10.9 20.3 4.0 1.9 3.3 24.8 2.5 10.7 3.8 6.8 10.4 12.8 6.6 10.3 3.0 12.5 5.2 5.6 15.4 2.5 7.5 4.7 15.6 10.3 4.3 13.3 3.3 0.9 2.9 3.0 12.6 1.4 1.4 2.3 8.2 4.4 9.8 5.2 2.8 3.3 18.5 18.9 13.1 22.4 19.2 15.5 18.2 18.5 27.9 15.5 TREX1 "AGS1, DRN3" ENSG00000213689 "Three prime repair exonuclease 1" Q9NSU2 3 48465811-48467645 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Exonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease mutation, Neurodegeneration, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 31.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035437, HPA046721" Supported Supported Cytosol Cytosol "HPA035437: AB_10672092, HPA046721: " 14.2 14.3 16.7 14.6 10.6 20.7 17.2 13.0 16.9 13.4 11.0 12.8 17.5 10.3 8.1 14.9 16.6 14.5 12.3 9.8 14.4 14.2 11.6 12.7 12.5 26.2 14.6 17.4 7.3 13.0 6.8 31.2 11.6 11.2 15.4 9.3 10.8 32.2 19.3 10.8 22.9 10.9 8.2 12.6 25.5 12.4 4.6 10.1 18.5 7.4 18.3 21.7 13.3 10.6 24.9 35.5 23.3 41.8 8.6 13.1 20.1 8.0 7.4 6.2 4.4 7.7 7.9 0.0 2.6 13.1 22.0 31.0 0.1 9.6 9.5 5.4 11.1 9.4 0.4 11.8 3.1 8.0 0.7 5.5 26.6 0.4 9.7 5.0 3.9 6.9 1.1 11.1 4.4 9.3 0.0 14.6 9.3 0.1 7.0 3.6 0.0 4.6 5.8 1.6 18.6 5.8 1.6 0.0 3.7 9.6 13.0 6.3 0.4 8.4 9.8 4.1 3.9 8.7 6.1 11.8 6.8 4.0 9.1 10.7 3.3 2.1 41.8 3.0 9.8 32.5 5.6 24.6 13.1 9.4 35.5 24.9 12.4 10.3 23.3 8.6 24.3 28.0 11.6 20.1 16.7 10.6 13.0 16.9 14.4 14.2 14.6 17.4 11.2 10.1 TREX2 ENSG00000183479 "Three prime repair exonuclease 2" Q9BQ50 X 153444720-153470587 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 39.6" "Cell line enhanced" "Detected in many" "HEK 293: 7.4;U-698: 10.1;U-937: 9.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.9;eosinophil: 5.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 5.7" "Not detected" "Not detected" HPA054060 Uncertain "HPA054060: " "unprognostic (2.32e-2)" "unprognostic (2.05e-3)" "unprognostic (1.13e-3)" "unprognostic (7.18e-4)" "unprognostic (6.05e-2)" "unprognostic (1.81e-2)" "unprognostic (8.40e-2)" "unprognostic (2.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (1.52e-1)" "unprognostic (9.34e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-2)" 3.2 1.5 2.1 3.4 3.0 1.9 2.1 1.1 3.6 4.3 2.6 1.9 15.5 1.4 2.5 2.2 4.5 2.6 2.2 3.5 1.6 1.2 2.8 4.6 2.4 3.1 2.4 2.4 2.1 2.2 1.5 1.7 2.6 2.7 2.5 1.4 1.4 4.5 7.4 2.0 39.6 2.3 1.9 1.2 4.3 1.7 2.1 1.9 5.8 3.3 6.2 4.7 2.2 5.2 0.4 0.3 5.7 0.1 0.2 0.4 0.2 2.8 3.5 0.3 1.3 0.5 0.7 0.3 0.9 0.8 0.7 2.0 1.0 0.7 0.3 1.8 0.8 3.1 1.2 2.0 0.0 3.1 7.4 0.3 0.7 0.4 0.3 0.8 1.9 0.8 1.8 0.8 0.7 0.3 0.4 3.5 0.2 3.3 2.0 2.2 1.1 2.4 4.8 1.0 2.2 0.3 1.0 0.8 0.4 0.3 0.3 1.0 0.5 0.9 0.0 1.3 2.3 2.8 1.0 3.9 2.7 10.1 0.3 9.4 1.5 3.9 0.0 5.7 0.3 0.0 0.2 0.4 0.1 0.3 0.3 0.3 0.4 0.1 0.0 0.2 0.1 0.0 0.1 0.2 2.1 3.0 1.1 3.6 1.6 1.2 2.4 2.4 2.7 1.9 TUFM "EF-TuMT, EFTu" ENSG00000178952 "Tu translation elongation factor, mitochondrial" P49411 16 28842411-28846408 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Elongation factor" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018991, HPA024087, CAB075730, CAB075731, CAB075732" Enhanced Enhanced Mitochondria 2800000 Mitochondria "CAB075730: , CAB075731: , CAB075732: , HPA018991: AB_1858458, HPA024087: AB_1858459" "unprognostic (1.40e-1)" "unprognostic (7.56e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (2.55e-2)" "unprognostic (3.39e-1)" "unprognostic (1.23e-3)" "unprognostic (8.05e-2)" "unprognostic (8.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "prognostic favourable (2.69e-6)" "unprognostic (5.26e-2)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (7.36e-2)" 27.3 47.8 28.8 32.3 31.3 27.2 40.4 22.3 41.4 25.3 41.7 27.1 34.4 44.0 26.6 22.3 40.0 32.7 37.6 69.2 25.6 25.8 45.6 68.4 28.6 46.2 33.1 24.4 25.9 75.0 48.3 22.7 23.0 27.3 23.4 37.6 25.4 40.9 33.1 77.3 28.1 36.1 26.2 25.8 28.4 36.9 47.0 21.5 32.5 37.0 55.4 33.9 26.8 23.3 30.6 57.3 21.7 44.2 25.5 38.8 45.4 29.1 55.4 17.8 37.1 25.8 23.7 36.5 21.4 24.9 34.1 32.4 59.7 32.3 65.6 39.5 21.4 57.2 42.1 41.4 20.5 26.1 64.4 25.0 44.8 72.2 30.7 44.8 23.3 30.2 32.8 36.9 36.7 40.6 56.1 25.9 24.8 59.4 42.9 43.8 39.8 34.4 59.5 32.3 95.4 29.5 28.6 31.2 38.1 18.7 66.7 29.2 39.7 36.5 25.8 20.4 23.8 25.3 32.6 39.6 40.9 28.5 26.1 56.3 26.7 21.7 44.2 19.5 31.3 42.3 34.8 30.6 29.7 32.7 57.3 27.5 28.5 29.5 9.1 25.5 31.6 34.9 38.8 45.4 28.8 31.3 22.3 41.4 25.6 25.8 33.1 24.4 27.3 21.5 TUT1 "FLJ21850, FLJ22267, FLJ22347, PAPD2, RBM21, TUTase" ENSG00000149016 "Terminal uridylyl transferase 1, U6 snRNA-specific" Q9H6E5 11 62575045-62592177 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA069055, HPA071838" Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA069055: , HPA071838: " "unprognostic (3.81e-2)" "unprognostic (3.54e-2)" "prognostic unfavourable (9.51e-4)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.59e-2)" "unprognostic (1.83e-1)" "unprognostic (2.59e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (2.71e-1)" "unprognostic (7.20e-3)" "unprognostic (1.03e-2)" "unprognostic (4.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.97e-3)" 10.9 12.1 10.7 9.9 13.6 7.8 12.9 13.5 13.3 10.5 8.7 15.9 13.0 12.9 11.5 10.8 10.0 16.9 13.7 10.7 13.6 8.3 12.2 22.7 9.6 18.1 15.5 9.5 14.5 26.2 15.5 16.2 12.3 13.0 13.9 6.2 11.9 16.4 11.9 20.5 13.9 11.7 10.2 11.4 14.6 12.5 18.6 13.2 17.1 14.0 8.8 13.6 11.5 9.8 13.1 9.4 6.6 7.3 9.8 16.0 7.2 7.2 9.1 6.3 8.8 7.7 4.4 8.2 7.8 4.8 6.6 5.8 8.2 14.2 11.6 18.1 3.8 13.7 11.6 9.1 3.4 8.9 6.1 11.9 9.3 7.7 8.6 8.4 5.4 6.2 9.8 8.3 12.6 6.3 17.8 12.0 5.6 15.9 11.9 17.9 7.2 11.2 13.4 10.1 28.1 6.1 4.2 10.5 14.7 6.0 11.3 9.7 15.8 8.2 5.7 7.5 6.8 8.7 5.9 20.9 18.3 14.2 8.8 6.7 6.2 5.9 5.9 6.6 10.5 7.3 14.6 9.8 9.9 8.4 7.8 13.1 16.0 12.5 3.6 9.8 5.3 9.4 8.9 7.2 10.7 13.6 13.5 13.3 13.6 8.3 15.5 9.5 13.0 13.2 TXNRD1 "GRIM-12, Trxr1, TXNR" ENSG00000198431 "Thioredoxin reductase 1" Q16881 12 104215779-104350305 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 143.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001395, CAB004607, CAB015834, HPA043871" Approved Supported Nucleoplasm 5900000 Nucleoplasm "CAB004607: AB_628405, CAB015834: , HPA001395: AB_1858377, HPA043871: " "unprognostic (2.52e-2)" "unprognostic (1.16e-1)" "unprognostic (5.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (1.94e-2)" "prognostic unfavourable (1.12e-5)" "unprognostic (5.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavourable (1.20e-5)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.18e-2)" "unprognostic (8.80e-2)" 19.1 79.2 14.1 15.6 16.9 22.6 18.5 11.1 13.7 13.0 21.8 9.7 19.7 23.5 23.5 14.7 16.7 19.0 23.2 32.4 11.0 11.7 25.3 19.6 29.3 18.1 12.0 10.9 16.4 7.9 10.5 16.2 30.8 16.4 25.3 19.1 18.1 10.6 26.5 30.0 5.7 17.0 99.6 10.9 14.9 24.2 14.8 8.9 15.6 16.5 16.9 13.2 73.2 72.0 8.1 14.2 37.6 16.2 8.3 10.2 8.7 22.0 102.6 11.9 11.2 57.5 32.2 41.6 41.0 26.0 18.5 19.2 10.8 32.9 16.5 19.1 143.4 7.7 23.5 15.7 22.0 8.0 10.2 13.9 80.6 45.6 92.3 21.7 15.2 18.3 16.2 40.9 13.1 63.4 19.1 7.8 27.7 10.6 22.2 9.9 11.5 105.8 22.0 8.3 14.3 21.5 12.1 18.6 11.2 33.1 52.4 32.7 12.4 12.8 84.7 9.1 18.9 20.3 33.5 8.6 16.8 24.8 19.1 12.0 53.9 33.0 10.6 24.7 9.1 14.0 10.2 8.1 8.4 9.0 14.2 5.2 7.6 6.6 37.6 8.3 16.2 9.2 7.1 8.7 14.1 16.9 11.1 11.2 11.0 11.7 12.0 10.9 16.4 8.9 TXNRD2 "TR, TR3, TRXR2" ENSG00000184470 "Thioredoxin reductase 2" Q9NNW7 22 19875517-19941992 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2 OS: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002007, HPA003323" Supported Supported Mitochondria,Cytosol 410000 Mitochondria Cytosol "CAB002007: , HPA003323: AB_1080396" "unprognostic (3.17e-2)" "unprognostic (8.72e-2)" "unprognostic (4.30e-1)" "unprognostic (9.71e-3)" "unprognostic (7.25e-2)" "unprognostic (6.35e-2)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (2.83e-1)" "unprognostic (4.94e-3)" "unprognostic (2.49e-1)" "prognostic favourable (1.10e-7)" "unprognostic (2.47e-1)" "unprognostic (5.99e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" 9.8 30.2 8.5 8.3 10.1 11.6 7.4 19.0 15.0 8.3 10.3 9.0 7.6 9.2 11.9 12.3 8.8 8.4 13.0 22.6 8.3 7.5 13.9 40.9 10.8 8.4 7.8 9.7 11.9 13.0 9.9 9.9 14.0 7.1 17.9 4.5 10.0 15.2 8.8 16.5 6.0 10.2 5.4 5.6 11.2 14.6 10.5 6.8 4.9 12.6 9.2 10.5 7.5 7.9 4.8 9.1 5.8 12.1 4.8 4.9 4.9 6.3 13.2 1.2 5.1 2.4 3.4 3.0 6.1 7.2 11.1 8.2 12.2 6.6 3.5 14.9 6.4 11.3 6.1 8.4 4.2 6.7 15.1 5.9 10.5 7.2 4.6 6.6 2.9 3.3 6.4 5.7 4.8 31.4 32.8 6.0 8.6 15.4 2.2 9.9 6.1 9.4 3.4 29.3 3.2 6.7 6.9 6.5 5.7 10.5 13.8 7.0 11.2 9.0 17.4 8.1 48.8 6.7 12.8 6.0 4.4 2.2 7.8 5.1 10.2 3.2 12.1 5.8 4.3 9.2 3.3 4.8 3.8 3.9 9.1 3.6 4.9 4.0 1.3 4.8 8.7 3.4 2.4 4.9 8.5 10.1 19.0 15.0 8.3 7.5 7.8 9.7 7.1 6.8 TXNRD3 "TGR, TR2, TRXR3" ENSG00000197763 "Thioredoxin reductase 3" Q86VQ6 3 126607052-126655155 "Enzymes, Predicted intracellular proteins" "Differentiation, Electron transport, Spermatogenesis, Transport" "Developmental protein, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 4.0" "Lineage enriched" "Detected in single" 4 "T-cells: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020802, HPA036109" Uncertain Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB020802: , HPA036109: " "unprognostic (1.41e-1)" "unprognostic (1.55e-2)" "unprognostic (3.92e-1)" "prognostic unfavourable (3.35e-4)" "unprognostic (3.90e-1)" "unprognostic (2.96e-1)" "unprognostic (3.01e-1)" "unprognostic (3.39e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "prognostic unfavourable (2.86e-4)" "unprognostic (3.14e-1)" "prognostic favourable (2.72e-4)" "unprognostic (5.94e-2)" "unprognostic (1.74e-1)" "unprognostic (1.03e-2)" "unprognostic (2.51e-1)" 5.4 5.9 4.9 2.4 4.7 0.9 7.2 5.5 5.7 7.3 4.2 4.6 5.5 1.6 8.3 7.1 6.4 4.7 5.2 4.9 4.0 2.9 6.7 10.0 7.0 5.2 4.6 3.5 8.8 7.1 12.3 8.5 3.3 7.0 5.2 3.6 6.4 5.7 5.1 7.3 4.8 2.6 8.1 5.1 3.3 4.9 27.8 5.8 5.0 7.4 3.6 2.1 6.6 5.3 0.3 0.7 0.5 0.9 0.9 4.0 0.3 13.7 3.5 4.5 7.1 8.4 12.7 2.3 6.1 5.5 5.0 7.1 6.3 7.8 0.0 7.8 8.4 5.5 5.6 6.3 6.3 0.0 4.1 1.6 3.3 4.8 7.2 5.5 0.5 11.6 5.5 1.7 11.6 3.6 3.3 0.0 8.0 9.9 1.1 3.0 6.4 2.7 0.4 3.9 2.2 5.3 6.9 7.8 4.8 17.4 5.1 8.8 7.0 2.1 6.0 6.1 1.5 8.3 2.8 3.6 1.5 0.0 3.3 1.9 5.2 0.0 0.9 0.5 0.5 0.8 0.1 0.0 0.2 0.6 0.7 0.3 4.0 1.3 0.0 0.9 0.2 0.0 0.0 0.3 4.9 4.7 5.5 5.7 4.0 2.9 4.6 3.5 7.0 5.8 UCK1 "FLJ12255, URK1" ENSG00000130717 "Uridine-cytidine kinase 1" Q9HA47 9 131523801-131531268 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050969 Approved Approved Nucleoplasm Nucleoplasm "HPA050969: " "unprognostic (2.20e-1)" "prognostic favourable (3.19e-4)" "unprognostic (1.16e-2)" "unprognostic (1.74e-3)" "unprognostic (7.29e-2)" "unprognostic (1.43e-1)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.54e-1)" "prognostic favourable (2.21e-7)" "unprognostic (5.11e-2)" "unprognostic (3.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.07e-1)" 13.2 15.9 21.7 13.7 22.5 13.7 15.6 29.9 23.2 15.0 15.6 17.3 20.8 11.4 12.2 19.3 14.5 17.6 16.5 21.0 19.6 18.4 18.3 26.7 12.7 12.9 20.4 19.1 21.3 24.0 17.6 14.4 16.4 14.8 14.9 9.2 17.6 24.1 18.3 30.0 12.0 12.2 14.8 19.9 12.1 13.4 15.7 15.6 12.5 18.5 10.8 11.5 13.6 9.4 7.9 6.6 9.4 7.8 6.8 13.5 6.1 6.9 15.4 17.9 22.9 12.7 9.1 15.2 11.3 16.8 19.6 15.0 15.3 6.4 7.6 6.8 13.5 13.6 16.6 14.5 8.5 13.9 15.5 7.1 23.2 9.6 18.2 11.6 10.5 10.2 13.6 15.8 11.5 12.0 8.9 5.8 14.4 27.7 15.8 5.9 21.2 15.4 15.2 27.7 12.7 12.6 6.6 24.2 15.2 16.3 12.5 17.6 24.4 6.9 8.8 21.8 11.1 13.5 11.0 12.0 15.3 9.6 10.8 8.1 15.1 2.3 6.2 9.4 8.5 7.8 11.3 7.9 10.1 7.6 5.7 7.9 13.5 6.8 4.1 6.8 2.7 6.6 12.3 6.1 21.7 22.5 29.9 23.2 19.6 18.4 20.4 19.1 14.8 15.6 UCK2 UMPK ENSG00000143179 "Uridine-cytidine kinase 2" Q9BZX2 1 165827531-165911618 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 65.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057128 Approved Nucleoplasm Nucleoplasm "HPA057128: " "unprognostic (5.37e-2)" "unprognostic (1.75e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-2)" "unprognostic (4.54e-2)" "unprognostic (6.83e-3)" "prognostic unfavourable (9.22e-8)" "prognostic unfavourable (4.98e-4)" "prognostic unfavourable (6.70e-4)" "unprognostic (3.04e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-2)" "prognostic unfavourable (5.12e-13)" "unprognostic (2.49e-3)" "unprognostic (1.14e-1)" "unprognostic (2.01e-3)" "unprognostic (1.83e-1)" 12.5 7.1 6.5 11.1 8.6 11.6 17.5 16.9 9.6 9.3 18.4 8.9 11.0 15.3 10.1 15.3 20.5 8.8 9.0 9.6 6.4 6.6 6.6 14.6 11.1 10.3 10.5 6.6 7.5 17.6 7.9 9.4 65.8 11.2 8.1 19.9 5.0 16.1 9.9 20.9 15.0 24.8 10.0 8.2 7.7 13.2 7.2 7.9 13.1 6.4 12.4 12.3 9.0 11.1 3.4 14.7 0.8 5.6 3.4 3.9 2.0 25.2 26.3 14.2 12.7 7.3 12.2 23.1 27.9 20.6 29.8 34.0 25.0 27.8 12.5 19.9 17.3 20.8 26.6 32.8 26.7 22.9 22.5 14.5 22.6 25.6 18.2 28.3 11.1 11.5 16.9 56.2 35.1 19.6 38.3 18.0 26.7 18.3 25.1 18.2 38.9 25.5 11.5 15.6 42.5 13.8 16.5 21.4 25.3 19.9 39.4 19.3 24.3 27.0 20.4 16.7 23.3 18.9 29.5 24.2 36.0 46.3 14.4 18.8 12.7 0.8 5.6 0.1 1.8 3.7 3.9 3.4 1.7 2.4 14.7 3.4 0.0 1.4 0.2 3.4 3.2 14.0 2.2 2.0 6.5 8.6 16.9 9.6 6.4 6.6 10.5 6.6 11.2 7.9 UCKL1 "FLJ20517, URKL1" ENSG00000198276 "Uridine-cytidine kinase 1 like 1" Q9NWZ5 20 63939829-63956415 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004722, HPA004769" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA004722: AB_1080455, HPA004769: AB_1080453" "unprognostic (1.03e-1)" "unprognostic (2.77e-2)" "unprognostic (2.64e-1)" "unprognostic (8.34e-2)" "unprognostic (7.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.45e-1)" "unprognostic (1.29e-1)" "prognostic favourable (4.42e-4)" "unprognostic (5.87e-2)" "unprognostic (3.18e-2)" "unprognostic (9.11e-2)" "unprognostic (2.81e-1)" "unprognostic (3.01e-1)" "unprognostic (5.26e-3)" 17.4 18.1 16.5 16.0 18.3 21.1 19.8 50.4 20.7 18.5 21.9 21.6 17.3 32.0 18.0 17.7 19.7 17.9 12.0 21.0 17.1 9.4 21.3 20.6 15.6 18.3 20.3 11.5 31.7 22.6 14.1 22.1 17.5 15.7 19.4 9.1 31.0 28.9 24.4 52.3 27.9 29.8 18.1 11.8 26.7 20.1 11.5 19.7 16.7 24.1 33.1 20.1 16.2 21.2 22.2 8.9 6.3 14.0 5.3 14.8 7.9 11.3 12.1 10.4 13.9 7.7 6.6 16.8 9.1 6.3 19.0 9.5 28.9 8.9 11.5 15.5 5.9 18.7 8.1 12.6 3.8 4.8 13.6 8.7 24.2 42.2 8.5 14.8 16.7 9.2 11.3 7.6 6.3 8.7 12.3 12.3 5.9 14.6 17.4 25.9 7.7 28.4 17.8 7.8 19.8 7.8 16.5 24.8 14.5 13.2 13.0 14.0 13.6 13.5 9.6 20.2 7.6 13.1 11.8 12.9 6.9 5.3 10.3 10.7 7.6 4.2 7.7 6.3 13.2 12.9 14.8 22.2 12.8 11.2 8.9 12.7 7.5 9.0 1.2 5.3 14.0 5.1 13.5 7.9 16.5 18.3 50.4 20.7 17.1 9.4 20.3 11.5 15.7 19.7 UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108733 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "hTERT-HME1: 102.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA054040: , HPA055394: AB_2682805" "unprognostic (1.16e-1)" "prognostic unfavourable (1.02e-4)" "unprognostic (5.96e-2)" "unprognostic (1.01e-1)" "unprognostic (3.21e-3)" "unprognostic (6.36e-2)" "unprognostic (1.78e-3)" "prognostic unfavourable (1.97e-4)" "unprognostic (3.81e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (1.52e-3)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" 16.7 8.4 2.8 12.6 4.2 17.6 7.1 5.7 3.8 10.3 8.0 1.7 2.1 7.5 2.8 4.2 37.7 3.3 8.5 7.0 2.3 3.3 12.4 9.1 18.3 17.4 5.8 1.4 2.9 5.8 2.4 5.0 28.9 5.5 3.0 7.6 2.9 7.5 2.1 5.1 2.0 9.7 5.2 3.9 13.9 2.5 1.8 4.8 1.2 6.2 34.0 19.4 7.9 19.6 0.6 8.2 15.7 22.0 5.7 19.7 16.0 6.5 7.8 0.8 1.6 2.6 1.2 8.0 3.2 4.4 4.1 5.1 3.2 3.1 0.0 1.1 2.6 4.5 1.5 13.0 2.6 1.3 1.4 0.2 1.8 1.3 2.4 0.2 0.5 1.6 6.3 1.8 102.5 2.6 0.4 3.8 2.1 0.7 0.0 1.1 3.1 6.8 0.0 1.7 1.7 9.4 3.3 0.7 0.7 3.3 0.9 23.7 0.8 0.2 3.7 9.6 8.2 2.6 8.1 7.4 9.9 1.1 9.7 0.9 23.2 15.7 22.0 15.1 19.7 16.7 12.5 0.2 12.6 13.5 8.2 0.6 13.0 12.0 9.1 5.7 15.9 0.7 11.2 16.0 2.8 4.2 5.7 3.8 2.3 3.3 5.8 1.4 5.5 4.8 UPP2 "UDRPASE2, UP2, UPASE2" ENSG00000007001 "Uridine phosphorylase 2" O95045 2 157876702-158136154 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 40.1;liver: 22.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.0;REH: 1.5" "Cancer enriched" "Detected in some" 6 "liver cancer: 3.6" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035225, HPA035226" Approved Nucleoplasm,Vesicles,Mitochondria Nucleoplasm "Vesicles, Mitochondria" "HPA035225: AB_10604002, HPA035226: AB_10696503" "unprognostic (1.87e-1)" "unprognostic (2.33e-1)" "unprognostic (4.22e-3)" "unprognostic (1.36e-3)" "unprognostic (2.29e-1)" "unprognostic (1.55e-1)" "unprognostic (3.53e-2)" "unprognostic (5.51e-2)" "unprognostic (5.11e-2)" "unprognostic (1.23e-2)" "unprognostic (4.65e-3)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (4.89e-2)" "unprognostic (2.78e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" 1.2 0.4 1.8 0.3 4.1 0.3 1.6 6.9 2.0 0.4 0.3 1.5 0.7 0.3 1.2 2.4 1.0 0.4 2.5 0.8 2.9 1.2 40.1 22.1 0.3 0.4 1.2 0.9 0.6 0.4 0.3 3.9 0.4 1.3 2.3 0.3 1.1 1.7 0.7 0.3 0.6 0.4 0.3 2.3 0.3 0.3 0.4 1.0 0.0 0.5 0.0 0.7 0.4 0.2 0.8 0.0 1.0 0.1 0.0 0.2 0.0 0.3 0.2 0.6 0.6 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.2 0.2 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.1 1.2 1.3 1.5 0.3 0.0 0.3 0.6 0.7 0.4 0.5 0.5 0.0 0.8 0.2 0.0 0.2 0.3 0.0 0.0 1.3 0.1 0.4 0.4 1.3 0.4 1.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.8 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.0 1.8 4.1 6.9 2.0 2.9 1.2 1.2 0.9 1.3 1.0 ZCCHC11 "KIAA0191, PAPD3, TUT4" ENSG00000134744 "Zinc finger CCHC-type containing 11" Q5TAX3 1 52408282-52553487 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027412, HPA027973" Supported Supported Nucleoli,Cytosol Cytosol Nucleoli "HPA027412: AB_1852281, HPA027973: AB_10603242" "unprognostic (2.74e-2)" "unprognostic (1.67e-2)" "unprognostic (1.19e-2)" "unprognostic (3.48e-2)" "unprognostic (1.36e-2)" "unprognostic (1.85e-3)" "prognostic unfavourable (9.00e-4)" "unprognostic (2.64e-1)" "unprognostic (5.05e-2)" "unprognostic (3.84e-1)" "unprognostic (6.57e-3)" "unprognostic (3.11e-2)" "unprognostic (5.35e-3)" "unprognostic (2.26e-1)" "unprognostic (1.67e-1)" "unprognostic (7.08e-2)" "unprognostic (2.33e-1)" 13.8 19.1 18.4 25.6 19.0 20.5 18.7 50.9 21.3 22.4 13.3 11.8 16.1 7.7 22.1 22.0 11.5 16.8 14.0 13.5 17.8 16.5 14.2 17.7 13.3 27.4 15.4 14.6 28.3 17.6 34.4 56.0 18.8 16.3 16.1 10.5 12.1 12.6 20.6 44.6 28.1 17.1 20.3 26.6 20.9 12.3 24.9 21.1 31.9 23.9 14.6 25.1 18.3 17.0 23.2 26.0 26.7 4.3 10.3 15.0 2.2 10.4 9.9 24.4 16.5 9.6 12.3 16.9 9.3 13.6 13.6 15.7 10.2 5.5 22.3 11.0 12.9 8.7 18.3 9.8 17.3 18.2 16.7 23.5 12.8 21.2 15.9 25.4 13.4 14.5 21.9 14.5 18.0 9.4 19.1 11.2 11.3 0.1 25.3 18.2 17.7 12.6 22.5 24.8 17.4 14.6 8.6 13.1 13.0 14.3 6.1 13.9 8.5 13.4 7.9 10.6 14.3 9.7 11.3 24.5 32.1 32.1 7.0 13.9 7.6 26.7 4.3 13.8 11.8 1.7 8.8 19.1 12.4 9.5 2.1 23.2 15.0 9.9 16.2 10.3 1.4 26.0 9.3 2.2 18.4 19.0 50.9 21.3 17.8 16.5 15.4 14.6 16.3 21.1 ZCCHC6 "FLJ13409, KIAA1711, PAPD6, TUT7" ENSG00000083223 "Zinc finger CCHC-type containing 6" Q5VYS8 9 86287733-86354454 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 42.1" "Group enriched" "Detected in all" 5 "granulocytes: 42.1;monocytes: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020615, HPA020620" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA020615: AB_1858983, HPA020620: AB_1858984" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.64e-1)" "unprognostic (1.26e-2)" "unprognostic (3.66e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-2)" "unprognostic (2.49e-2)" "unprognostic (4.43e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (3.07e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (1.40e-1)" 11.2 9.3 7.7 22.6 11.2 17.0 17.3 9.7 13.7 10.8 13.5 5.6 12.8 9.4 8.6 8.1 23.1 8.3 10.3 10.1 9.4 5.2 7.4 33.1 16.3 19.5 9.8 5.1 9.0 12.9 9.2 18.6 33.3 9.0 19.3 10.8 4.5 14.0 13.6 12.5 30.9 15.6 9.7 13.6 22.2 11.7 10.3 10.7 23.3 8.7 15.2 16.9 13.7 14.3 4.4 4.3 42.1 15.7 4.5 5.7 2.9 9.8 10.7 6.4 9.2 16.3 24.8 7.8 13.5 13.2 6.0 7.0 4.8 8.8 14.1 12.3 8.9 17.5 7.5 7.6 8.9 16.5 4.0 10.1 11.3 9.0 13.9 11.5 14.8 16.4 16.0 9.5 11.3 10.0 9.5 15.3 16.6 10.6 9.6 7.0 5.2 7.2 4.9 11.1 6.5 10.6 19.4 4.6 3.7 8.2 10.9 4.7 4.1 5.2 15.4 5.7 6.9 10.1 9.2 17.7 13.7 10.5 13.6 6.9 7.5 11.5 7.1 7.1 5.7 9.1 4.9 4.4 3.2 4.1 4.3 4.4 3.7 4.0 42.1 4.5 15.7 2.0 3.0 2.9 7.7 11.2 9.7 13.7 9.4 5.2 9.8 5.1 9.0 10.7 ZNRD1 "HTEX-6, hZR14, RPA12, tctex-6" ENSG00000066379 "Zinc ribbon domain containing 1" Q9P1U0 6 30058899-30064909 "Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055074, HPA077979" Supported Supported "Nucleoli fibrillar center" "Nucleoli fibrillar center" "HPA055074: , HPA077979: " "unprognostic (4.94e-2)" "unprognostic (2.93e-2)" "unprognostic (2.54e-1)" "unprognostic (3.81e-1)" "unprognostic (3.88e-2)" "unprognostic (8.55e-2)" "unprognostic (5.36e-2)" "unprognostic (2.82e-3)" "unprognostic (1.96e-1)" "unprognostic (9.52e-3)" "unprognostic (5.18e-1)" "unprognostic (3.28e-1)" "prognostic unfavourable (2.17e-7)" "unprognostic (2.57e-1)" "unprognostic (1.51e-1)" "unprognostic (9.97e-2)" "prognostic favourable (2.75e-5)" 11.7 13.5 6.7 14.1 7.2 8.7 17.1 7.4 8.9 12.3 15.3 6.8 9.1 13.2 12.5 10.2 15.4 13.0 10.4 11.0 6.4 6.3 13.4 12.2 14.8 18.8 8.3 6.1 13.6 22.0 10.2 9.4 11.4 6.2 12.5 14.5 9.7 14.7 10.2 13.5 11.2 14.2 9.1 6.3 17.5 12.7 22.9 6.8 37.0 15.0 15.3 18.9 12.2 15.0 8.2 8.4 6.4 5.9 8.1 13.0 7.9 4.2 0.9 4.7 6.7 2.3 2.8 1.8 1.6 2.5 3.0 2.7 4.7 3.0 3.4 1.4 2.7 3.6 7.8 6.4 3.2 2.4 7.9 8.0 2.1 7.0 9.5 8.4 3.7 5.5 3.7 4.7 16.1 8.1 13.4 2.1 2.0 5.7 7.2 18.3 0.0 5.6 8.9 4.4 6.6 2.6 7.0 1.7 3.2 2.9 4.5 2.7 3.4 7.0 1.7 3.5 3.0 0.0 5.2 5.3 10.0 10.9 1.3 13.7 4.6 6.2 5.9 5.7 12.5 5.6 13.0 7.3 10.8 11.5 5.6 8.2 9.8 10.2 6.4 8.1 5.2 8.4 10.9 7.9 6.7 7.2 7.4 8.9 6.4 6.3 8.3 6.1 6.2 6.8