Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" ACOT12 "Cach, STARD15, THEAL" ENSG00000172497 "Acyl-CoA thioesterase 12" Q8WYK0 5 81330005-81394179 "Enzymes, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 49.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.0;CACO-2: 2.4;Karpas-707: 1.8;SK-MEL-30: 4.1" "Cancer enriched" "Detected in single" 76 "liver cancer: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037723, HPA037724" Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA037723: AB_10672606, HPA037724: " "unprognostic (6.06e-2)" "unprognostic (1.39e-1)" "prognostic favourable (5.30e-4)" "unprognostic (7.68e-2)" "unprognostic (8.22e-2)" "unprognostic (5.68e-3)" "unprognostic (2.46e-1)" "unprognostic (6.86e-2)" "unprognostic (1.46e-2)" "unprognostic (3.07e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.2 49.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.4 0.1 0.0 0.1 2.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276367-99291028 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 322 "liver: 250.3" "Cell line enriched" "Detected in some" 5 "ASC diff: 10.9" "Cancer enriched" "Detected in some" 251 "liver cancer: 165.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Plasma membrane,Cytosol" 12000000 "Plasma membrane, Cytosol" "CAB009562: AB_2257984, HPA047814: , HPA060902: " "unprognostic (5.89e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "prognostic favourable (2.38e-4)" "unprognostic (2.78e-3)" "unprognostic (4.25e-1)" "unprognostic (4.79e-3)" "unprognostic (6.21e-2)" "unprognostic (9.36e-2)" "unprognostic (3.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 250.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 10.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304964-99352760 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adipose tissue: 253.5;liver: 466.3" "Cell line enriched" "Detected in some" 7 "ASC diff: 385.0" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Group enriched" "Detected in some" 5 "midbrain: 2.3;pons and medulla: 1.6" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" 16000000 "Plasma membrane, Cytosol" "HPA047814: , HPA060902: " "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavourable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" 253.5 12.3 0.2 21.8 0.0 0.4 78.7 0.2 0.4 18.3 60.0 0.4 5.7 3.5 12.8 14.4 33.5 22.3 31.9 24.2 0.3 0.0 9.2 466.3 43.8 17.5 2.3 0.1 18.0 8.7 0.8 5.3 0.9 1.6 30.7 10.1 2.3 11.2 3.9 20.5 11.9 25.4 30.8 2.4 5.9 10.9 18.0 0.2 0.2 16.1 9.7 2.0 42.3 76.0 0.6 0.2 1.2 0.3 0.8 0.4 0.0 0.0 0.0 0.0 0.0 385.0 56.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.3 0.2 0.1 0.1 0.2 0.4 0.1 0.0 0.6 0.3 0.4 1.2 0.8 0.1 0.2 0.1 0.0 0.2 0.0 0.2 0.0 0.3 0.0 2.3 0.1 1.6 0.2 ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336492-99353027 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 47.1;liver: 149.4;stomach 1: 43.1" "Group enriched" "Detected in some" 4 "ASC TERT1: 5.1;HSkMC: 15.1" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" 9700000 "Plasma membrane, Cytosol" "HPA047814: , HPA060902: " "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favourable (4.55e-4)" "prognostic favourable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" 4.7 0.0 0.0 18.5 0.0 0.0 1.1 0.0 0.0 1.1 37.9 0.0 1.1 43.4 0.3 1.2 1.7 0.0 12.0 2.0 0.0 8.3 149.4 1.1 0.0 0.2 0.0 1.1 11.4 0.0 0.0 0.0 0.0 2.5 13.6 0.0 1.1 0.8 6.0 0.0 47.1 0.9 0.5 0.0 43.1 1.6 0.0 0.0 0.5 2.0 0.2 1.3 0.7 0.2 0.2 0.3 0.1 0.1 0.3 0.1 0.0 2.2 0.0 0.1 1.7 5.1 1.1 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.3 0.1 0.5 1.4 0.3 15.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.9 0.4 0.1 0.1 0.9 2.1 0.9 0.0 0.4 1.6 0.7 0.8 0.0 0.2 0.0 0.1 0.0 0.6 0.3 0.2 0.1 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.3 0.1 0.0 0.2 0.0 0.1 ADH4 ADH-2 ENSG00000198099 "Alcohol dehydrogenase 4 (class II), pi polypeptide" P08319 4 99123657-99157792 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "liver: 345.2" "Cell line enriched" "Detected in some" 11 "Hep G2: 21.9" "Cancer enriched" "Detected in some" 60 "liver cancer: 230.7" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020525 Enhanced Uncertain Nucleoplasm,Cytosol 5300000 "Nucleoplasm, Cytosol" "HPA020525: AB_1844609" "unprognostic (2.75e-1)" "unprognostic (1.69e-2)" "unprognostic (1.85e-2)" "unprognostic (5.54e-3)" "unprognostic (2.14e-2)" "unprognostic (1.33e-2)" "prognostic favourable (7.08e-6)" "unprognostic (1.49e-1)" "unprognostic (1.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.88e-1)" "unprognostic (2.34e-2)" "unprognostic (7.16e-3)" "unprognostic (2.20e-1)" "unprognostic (5.89e-3)" 0.3 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.2 3.6 0.0 0.1 11.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.2 345.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.4 0.1 4.5 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.8 0.1 0.1 0.5 1.2 0.7 2.8 0.5 0.4 0.9 0.1 0.3 0.3 0.2 0.3 0.4 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.2 0.5 0.3 0.0 0.3 0.0 0.2 0.4 0.2 0.1 0.5 0.8 21.9 0.1 1.8 0.5 0.3 0.0 0.2 0.2 0.1 0.4 1.0 0.1 0.3 0.3 0.6 0.3 0.2 0.2 1.8 0.5 0.2 0.4 0.2 0.3 2.0 0.3 0.0 0.5 0.0 0.4 0.5 0.2 0.4 0.1 0.6 0.4 0.7 0.1 0.7 0.1 2.8 0.4 0.5 0.9 0.5 0.8 0.4 0.5 0.5 0.1 1.2 0.8 0.8 1.0 0.4 0.5 0.7 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044578, HPA061919" Approved 6800000 "HPA044578: , HPA061919: AB_2684638" "unprognostic (1.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-3)" "prognostic favourable (9.90e-5)" "unprognostic (2.63e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "prognostic unfavourable (3.54e-4)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "prognostic favourable (4.58e-10)" "unprognostic (1.79e-3)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" 35.6 19.8 17.3 18.5 18.5 6.3 28.6 11.2 22.3 34.1 39.4 19.8 17.0 24.9 53.8 40.3 43.5 28.6 20.8 31.9 13.7 16.6 46.6 69.7 19.9 15.3 15.7 16.1 39.1 12.8 10.5 15.1 19.9 18.6 45.0 27.7 28.7 17.3 35.9 20.7 13.8 28.5 43.6 13.5 20.5 27.0 27.2 10.0 35.2 30.4 18.4 18.6 60.0 22.0 13.9 12.5 18.2 11.1 26.2 25.3 17.0 15.7 12.9 38.1 21.4 69.2 64.4 22.9 26.2 46.3 28.5 24.9 14.7 18.7 18.2 15.3 37.8 13.5 26.2 36.4 27.5 13.1 11.0 12.6 17.5 57.9 67.1 22.0 10.3 57.9 28.3 21.3 16.9 21.9 23.3 10.4 37.5 17.9 29.6 19.8 30.6 15.5 21.7 21.3 9.6 45.0 18.4 14.6 19.1 15.8 18.8 28.6 15.2 15.5 16.4 26.0 16.5 16.9 18.0 11.0 13.6 25.3 26.7 14.6 26.3 9.8 11.1 18.2 18.4 9.8 16.7 13.9 20.3 17.1 12.5 13.1 19.9 18.3 1.6 26.2 7.1 10.8 25.3 17.0 17.3 18.5 11.2 22.3 13.7 16.6 15.7 16.1 18.6 10.0 ADH6 ADH-5 ENSG00000172955 "Alcohol dehydrogenase 6 (class V)" P28332 4 99202638-99219537 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 123.3" "Cell line enriched" "Detected in some" 5 "Hep G2: 30.5" "Cancer enriched" "Detected in many" 18 "liver cancer: 46.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA067946, HPA069081" Enhanced 480000 "HPA067946: AB_2732776, HPA069081: AB_2732127" "unprognostic (1.38e-2)" "unprognostic (1.83e-2)" "unprognostic (5.82e-2)" "unprognostic (1.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.11e-3)" "unprognostic (2.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.35e-1)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (8.74e-3)" "unprognostic (3.86e-3)" 0.1 0.1 0.1 1.1 0.1 0.0 0.1 0.1 0.1 0.1 6.0 0.0 0.0 7.2 0.1 0.2 0.2 1.5 5.6 0.1 0.1 0.1 10.6 123.3 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.1 1.4 0.0 0.1 0.0 0.1 0.6 23.7 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.5 0.0 1.3 0.1 0.2 0.2 0.3 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 6.4 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.0 0.3 0.1 0.2 1.3 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 75.0;lymphoid tissue: 30.7;tongue: 68.7" "Group enriched" "Detected in some" 7 "ASC TERT1: 3.9;HaCaT: 4.4" "Group enriched" "Detected in some" 17 "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4;urothelial cancer: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 75.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 9.4 0.0 0.0 0.1 0.0 68.7 30.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADHFE1 "ADHFe1, FLJ32430" ENSG00000147576 "Alcohol dehydrogenase, iron containing 1" Q8IWW8 8 66430185-66471601 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.5" "Cell line enhanced" "Detected in some" "ASC diff: 4.6;HHSteC: 3.0;HSkMC: 2.7;RPTEC TERT1: 4.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023062 Enhanced Approved Vesicles Vesicles "HPA023062: AB_1844611" "prognostic favourable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favourable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favourable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" 12.5 3.2 10.3 2.2 9.7 1.8 4.3 2.2 10.7 5.9 3.8 10.9 4.8 2.7 4.2 8.6 3.1 5.9 5.0 34.6 6.9 5.4 11.8 44.5 3.6 2.3 8.6 7.5 5.2 8.3 11.6 9.8 3.7 6.9 7.3 3.1 10.7 6.6 10.5 35.7 2.4 2.4 6.9 4.8 2.8 8.6 3.2 7.3 0.0 4.5 12.9 2.5 6.2 1.9 1.3 0.4 3.4 1.1 2.2 2.6 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.5 0.4 0.3 0.0 0.0 1.7 0.0 0.0 0.7 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 3.0 0.0 0.2 2.7 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.9 0.0 0.5 1.2 2.0 0.0 0.0 0.3 0.2 0.0 0.0 1.2 0.1 0.1 0.8 0.0 0.3 3.4 1.1 0.0 2.6 0.0 2.4 1.3 0.5 2.2 0.4 0.8 0.7 2.2 0.1 2.2 0.0 0.3 0.0 0.6 10.3 9.7 2.2 7.8 6.9 5.4 8.6 7.5 6.9 7.3 AKR1A1 "ALR, DD3" ENSG00000117448 "Aldo-keto reductase family 1 member A1" P14550 1 45550543-45570049 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006246, HPA017919, HPA019649, HPA027734" Approved Supported Nucleoplasm,Cytosol 8100000 Cytosol Nucleoplasm "CAB006246: AB_425840, HPA017919: AB_1844695, HPA019649: AB_1844696, HPA027734: AB_10600976" "unprognostic (1.73e-1)" "prognostic favourable (2.66e-6)" "unprognostic (4.03e-1)" "prognostic favourable (2.92e-4)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (1.31e-3)" "unprognostic (2.52e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (8.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.56e-2)" "unprognostic (2.46e-1)" "unprognostic (2.89e-2)" "unprognostic (4.57e-2)" 20.0 20.4 12.0 27.9 13.9 9.7 31.8 11.5 23.6 21.7 39.6 18.7 20.0 43.6 18.5 31.7 39.0 21.8 31.7 18.5 11.2 12.0 79.6 80.4 26.0 33.8 15.0 13.9 18.3 44.2 11.3 27.5 20.2 13.1 19.4 28.9 16.7 59.8 24.1 13.4 18.2 69.7 19.4 16.3 25.6 27.7 10.5 13.1 24.8 24.6 31.3 33.2 17.4 18.6 23.3 46.8 26.8 56.3 13.8 18.7 38.4 16.4 23.8 21.8 16.8 47.4 34.5 15.4 19.6 45.7 17.1 34.5 9.9 12.7 40.7 15.7 22.3 21.1 22.9 28.5 16.1 16.4 20.6 23.5 20.2 43.4 39.6 30.3 26.4 38.0 25.8 21.6 40.2 39.5 12.0 32.6 20.0 11.9 32.4 13.2 23.7 16.4 37.4 26.2 47.1 48.6 22.5 26.0 15.0 16.9 67.6 24.7 18.9 17.4 24.0 7.9 17.6 27.4 11.6 22.5 29.9 19.1 15.5 39.6 6.8 26.8 56.3 10.5 16.3 51.8 17.8 23.3 15.3 16.0 46.8 22.7 13.1 13.5 2.6 13.8 38.1 40.8 18.7 38.4 12.0 13.9 11.5 23.6 11.2 12.0 15.0 13.9 13.1 13.1 AKR1B1 "ALDR1, AR" ENSG00000085662 "Aldo-keto reductase family 1 member B" P15121 7 134442350-134459284 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 302.2;seminal vesicle: 109.3" "Cell line enhanced" "Detected in many" "A549: 121.0;BJ hTERT+: 222.0;RPTEC TERT1: 105.0;U-87 MG: 99.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026425, CAB027391, CAB047353, HPA052751" Enhanced Supported Nucleoplasm,Cytosol 1700000 Cytosol Nucleoplasm "CAB027391: , CAB047353: , HPA026425: AB_10601563, HPA052751: " "unprognostic (2.76e-2)" "unprognostic (2.84e-2)" "unprognostic (2.02e-2)" "unprognostic (1.37e-2)" "unprognostic (6.81e-2)" "unprognostic (2.26e-1)" "unprognostic (4.18e-2)" "unprognostic (5.09e-2)" "unprognostic (2.51e-3)" "unprognostic (2.47e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "prognostic unfavourable (2.44e-5)" "unprognostic (2.03e-1)" "unprognostic (1.39e-1)" "prognostic unfavourable (7.00e-4)" 5.9 302.2 7.5 4.7 13.7 2.5 9.5 6.9 10.9 4.4 3.9 8.2 50.4 2.7 4.6 6.1 4.2 4.6 5.2 24.2 7.3 8.4 17.7 2.5 6.9 10.0 9.5 9.0 8.2 7.2 9.4 8.0 24.8 11.9 5.5 4.1 5.8 4.4 109.3 37.6 2.8 4.8 5.6 7.9 6.7 5.0 5.2 5.9 7.3 6.0 10.3 7.6 7.1 3.7 31.4 34.8 22.5 26.0 26.3 42.7 47.2 13.3 121.0 13.6 19.3 58.9 16.0 36.3 13.0 222.0 19.1 24.8 5.6 12.3 0.0 6.0 21.7 5.7 14.8 12.9 15.2 4.8 13.6 6.8 18.2 16.4 84.4 0.0 0.0 14.9 9.7 27.3 7.3 26.9 0.0 4.5 21.1 0.2 20.0 9.2 22.7 0.1 20.9 8.7 10.1 105.0 65.4 10.2 22.7 90.9 0.1 9.5 0.0 10.2 21.2 18.9 8.8 1.7 14.1 12.5 13.7 33.8 99.9 0.0 11.3 22.5 26.0 1.2 37.9 17.0 34.0 31.4 32.4 36.7 34.8 28.5 42.7 41.1 2.1 26.3 8.9 4.9 22.0 47.2 7.5 13.7 6.9 10.9 7.3 8.4 9.5 9.0 11.9 5.9 AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527592-134541408 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 41.5;intestine: 99.7;stomach 1: 68.6" "Group enriched" "Detected in some" 82 "A549: 252.0;Hep G2: 69.9" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 1.8" "Low lineage specificity" "Detected in single" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted in other tissues" 68000000 Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: " "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favourable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavourable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" 0.6 0.8 0.6 2.2 0.6 0.0 0.6 0.6 0.6 13.1 11.5 0.6 0.6 99.7 0.6 0.9 41.5 0.0 28.9 0.6 0.6 0.0 4.0 6.3 2.0 0.6 0.6 0.6 0.6 0.6 0.0 2.5 0.6 0.6 2.0 7.3 1.3 6.1 0.6 0.6 1.0 54.1 7.1 0.6 0.6 68.6 0.8 0.6 0.9 0.7 28.6 3.6 16.3 22.9 0.4 0.1 1.8 0.2 0.4 0.2 0.1 0.0 252.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 69.9 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.2 1.8 0.4 0.1 0.1 0.1 0.1 0.6 0.6 0.6 0.6 0.6 0.0 0.6 0.6 0.6 0.6 AKR7A2 AFAR ENSG00000053371 "Aldo-keto reductase family 7 member A2" O43488 1 19303965-19312146 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032587, CAB032841, HPA064638" Enhanced Supported Cytosol 2700000 Cytosol "CAB032587: AB_673379, CAB032841: AB_2224545, HPA064638: " "unprognostic (1.06e-1)" "unprognostic (3.48e-2)" "unprognostic (7.23e-2)" "unprognostic (5.76e-2)" "unprognostic (9.92e-2)" "unprognostic (1.09e-1)" "unprognostic (1.14e-2)" "unprognostic (3.14e-3)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (5.11e-2)" "unprognostic (7.11e-2)" "prognostic favourable (2.67e-4)" "unprognostic (3.72e-2)" "unprognostic (8.53e-2)" "unprognostic (1.01e-1)" "prognostic unfavourable (8.59e-4)" 21.2 39.0 25.2 14.0 26.9 15.2 22.0 19.8 26.2 32.9 38.5 28.1 28.7 56.0 20.2 23.0 25.7 35.1 31.9 31.2 22.0 19.4 49.3 32.4 14.4 21.9 24.9 26.2 31.6 60.8 14.8 19.0 17.2 23.6 19.9 19.5 25.8 21.4 24.9 33.8 18.8 43.1 20.8 20.0 16.3 22.3 21.6 21.4 24.7 22.9 20.2 18.3 16.7 21.6 23.0 40.1 13.7 29.0 22.2 27.1 23.5 24.2 15.3 16.8 15.5 26.7 26.0 11.2 18.1 22.2 25.5 22.9 19.4 20.5 17.6 19.4 24.3 19.4 18.8 27.3 12.1 14.0 29.8 11.0 14.8 31.0 20.8 12.1 8.9 25.8 21.6 19.5 12.0 21.5 16.0 16.5 26.0 24.2 23.6 11.8 4.8 19.3 24.9 21.0 31.0 24.8 10.7 31.7 11.8 19.8 17.9 30.5 35.6 42.4 16.8 16.0 16.9 17.1 13.5 20.1 12.6 21.4 34.5 27.9 22.5 0.1 29.0 13.7 23.0 23.7 26.8 23.0 20.7 20.3 40.1 21.4 23.9 20.6 3.4 22.2 17.8 35.0 27.1 23.5 25.2 26.9 19.8 26.2 22.0 19.4 24.9 26.2 23.6 21.4 ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605929-95656706 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 68.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Supported Mitochondria 23000 Mitochondria "HPA008333: AB_1078125, HPA012604: AB_1844721" "unprognostic (5.97e-3)" "unprognostic (2.08e-2)" "unprognostic (5.75e-2)" "prognostic favourable (4.20e-4)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-3)" "unprognostic (7.08e-2)" "unprognostic (4.06e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "prognostic unfavourable (3.60e-9)" "unprognostic (1.02e-3)" "unprognostic (6.57e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" 6.3 10.4 7.1 10.4 7.9 5.2 7.7 7.3 9.3 13.7 20.1 7.2 20.5 33.8 9.3 12.3 12.8 8.5 15.2 7.2 6.2 7.1 13.0 28.9 6.6 7.4 6.7 5.3 14.5 40.7 12.7 17.4 14.3 7.7 9.6 19.4 7.9 68.8 20.5 3.5 9.6 45.4 10.0 5.4 8.6 15.2 8.4 5.4 12.7 25.9 9.7 15.9 8.6 8.2 13.1 5.2 0.3 4.0 13.0 16.3 8.0 18.2 17.3 16.6 43.6 22.4 21.7 17.9 21.3 32.1 21.7 27.3 34.6 14.6 62.1 20.0 33.5 24.2 33.3 21.9 24.7 17.6 26.2 19.7 12.3 49.1 14.7 34.3 22.0 22.7 13.5 17.7 34.7 22.7 18.3 13.1 16.2 26.2 31.0 22.1 19.6 17.3 29.2 19.1 21.3 25.3 13.9 16.6 16.5 16.9 13.5 15.7 20.1 16.0 18.8 9.0 14.4 23.2 24.4 15.1 11.2 38.0 17.6 39.8 11.5 0.0 1.4 0.1 15.5 2.7 16.3 13.1 14.2 16.0 5.2 9.0 12.1 13.4 0.3 13.0 4.0 3.1 13.3 8.0 7.1 7.9 7.3 9.3 6.2 7.1 6.7 5.3 7.7 5.4 ALDH1A3 "ALDH6, RALDH3" ENSG00000184254 "Aldehyde dehydrogenase 1 family member A3" P47895 15 100877714-100916626 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 42.0;HaCaT: 52.3;HBEC3-KT: 129.5;U-2197: 74.4;U-87 MG: 59.2;WM-115: 61.1" "Group enriched" "Detected in many" 7 "melanoma: 16.8;prostate cancer: 80.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 1.0;eosinophil: 2.1;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.5;granulocytes: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046271, HPA064749" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA046271: AB_10965992, HPA064749: " "unprognostic (6.87e-2)" "unprognostic (2.23e-1)" "unprognostic (6.20e-3)" "unprognostic (1.21e-3)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (6.28e-2)" "unprognostic (5.46e-2)" "unprognostic (9.62e-2)" "unprognostic (4.53e-2)" "unprognostic (3.64e-2)" "unprognostic (2.56e-1)" "unprognostic (1.25e-2)" "unprognostic (2.61e-2)" "unprognostic (2.12e-1)" "unprognostic (7.34e-2)" "unprognostic (6.07e-3)" 30.3 5.7 2.3 14.9 1.6 0.0 11.1 4.1 2.6 14.2 11.5 1.6 10.5 5.2 5.9 37.9 10.5 11.5 15.0 6.1 2.1 2.0 3.7 1.7 4.2 5.5 2.6 1.7 9.0 7.4 3.2 13.2 5.1 3.9 51.9 3.2 49.9 41.5 19.2 6.1 1.7 15.6 14.2 6.4 1.5 5.3 15.9 0.7 0.6 0.9 15.2 18.9 18.0 9.8 0.3 1.5 2.1 0.2 0.0 0.0 0.1 42.0 5.6 0.0 0.0 9.3 4.1 0.1 0.3 0.3 0.2 0.1 0.1 33.7 0.3 0.5 11.3 52.3 1.0 129.5 0.8 0.0 0.2 0.2 2.3 0.0 3.1 0.1 0.2 2.9 3.6 2.9 0.5 0.4 0.0 0.2 0.2 0.4 0.0 0.2 1.1 34.2 0.0 0.5 0.2 0.0 35.3 0.0 3.0 13.1 11.5 3.9 1.1 0.3 6.6 0.0 0.1 74.4 1.6 0.0 0.3 0.2 59.2 0.0 61.1 1.0 0.2 2.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 2.3 1.6 4.1 2.6 2.1 2.0 2.6 1.7 3.9 0.7 ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392664-38398661 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 113.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021037 Approved Supported Nucleoplasm,Vesicles,Mitochondria 210000 Mitochondria "Nucleoplasm, Vesicles" "HPA021037: AB_1844724" "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favourable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavourable (1.17e-5)" "unprognostic (2.89e-2)" 7.4 4.9 2.1 16.8 2.1 0.6 5.4 1.1 5.4 5.8 25.4 1.7 6.1 7.0 27.3 10.7 21.6 16.7 30.8 11.6 3.1 2.0 18.0 55.2 3.5 5.9 2.4 2.0 12.2 14.6 1.4 1.4 1.6 3.0 22.7 11.5 5.2 5.9 18.2 19.4 3.0 11.2 113.9 2.7 2.8 15.8 7.8 1.7 1.6 6.3 7.0 2.0 54.5 8.3 5.9 9.4 1.2 10.5 7.5 10.2 5.1 23.9 22.3 6.9 11.0 9.8 11.7 5.5 11.5 5.8 9.7 10.0 14.9 4.7 15.1 6.9 16.1 3.4 22.7 24.3 9.7 16.9 9.8 7.5 16.4 44.2 7.1 11.9 8.5 13.9 5.3 7.9 6.9 9.2 21.6 14.8 14.7 9.1 0.0 4.8 20.5 10.0 4.9 41.8 11.5 8.7 10.8 15.1 7.0 8.7 5.8 6.7 5.5 9.3 6.2 11.2 18.6 9.3 14.3 2.2 4.3 6.0 5.8 12.2 7.6 0.2 4.2 0.2 7.3 9.1 10.2 5.9 7.0 6.6 9.4 3.1 5.8 6.8 1.2 7.5 10.5 1.3 4.8 5.1 2.1 2.1 1.1 5.4 3.1 2.0 2.4 2.0 3.0 1.7 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family (mitochondrial)" P05091 12 111766887-111817529 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 279.7" "Cell line enhanced" "Detected in many" "ASC diff: 26.2;HHSteC: 29.4;SK-BR-3: 59.1;THP-1: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 45.8;myeloid DC: 46.6" "Group enriched" "Detected in many" 4 "dendritic cells: 46.6;monocytes: 45.8" HPA051065 Approved 1400000 "HPA051065: " "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favourable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favourable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favourable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavourable (7.71e-4)" 88.9 34.0 42.1 17.0 44.6 9.9 39.6 14.3 30.9 10.4 25.3 17.5 16.8 25.6 9.0 11.6 26.4 10.3 28.5 45.0 30.9 24.2 59.0 279.7 38.1 13.3 34.1 32.6 16.1 14.0 2.2 7.6 4.0 30.6 13.5 26.2 13.1 17.9 30.7 40.1 43.5 25.5 29.4 26.6 8.0 34.9 9.5 23.8 3.3 12.0 28.1 18.2 17.0 22.9 1.4 46.6 10.8 45.8 0.7 0.2 21.7 2.4 3.8 5.5 9.4 26.2 3.9 18.0 2.6 4.9 1.2 0.9 6.7 3.5 0.1 13.5 5.9 4.7 0.0 1.3 0.8 0.1 1.8 0.2 2.4 18.2 29.4 0.2 0.2 7.2 6.7 4.4 0.1 7.8 4.9 0.8 1.2 0.1 0.2 6.6 7.3 0.6 0.1 0.1 0.5 9.1 0.1 2.2 6.8 6.6 59.1 0.0 5.9 26.3 0.3 0.1 5.0 0.1 0.1 1.6 0.8 7.1 6.5 0.2 0.1 0.9 45.8 10.8 0.1 20.1 0.2 1.4 0.0 0.1 46.6 1.2 0.1 0.1 2.3 0.7 5.0 15.5 0.1 21.7 42.1 44.6 14.3 30.9 30.9 24.2 34.1 32.6 30.6 23.8 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.2;lymphoid tissue: 70.3;stomach 1: 49.9;tongue: 106.6" "Cell line enriched" "Detected in some" 20 "A549: 321.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 1.8" "Cell type enhanced" "Detected in some" "NK-cell: 2.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: , HPA063783: " "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favourable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 0.7 0.1 0.2 0.8 0.4 0.0 0.5 0.2 0.3 1.3 0.9 0.8 0.3 1.3 0.2 0.4 88.2 1.2 3.8 0.2 0.4 0.0 0.4 0.4 26.0 0.2 0.2 0.3 0.6 0.2 0.0 0.3 0.2 1.8 0.5 0.6 0.5 26.7 0.3 0.4 16.2 0.6 0.3 0.3 0.3 49.9 0.3 0.2 0.2 0.2 106.6 70.3 1.6 3.9 1.1 0.3 0.0 0.0 2.4 0.7 0.1 0.0 321.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 16.1 0.0 0.1 0.0 1.9 0.0 0.8 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 5.7 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.3 1.1 0.0 0.7 0.0 2.4 0.0 0.0 0.0 0.1 0.2 0.4 0.2 0.3 0.4 0.0 0.2 0.3 1.8 0.2 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19677598 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Approved "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favourable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 22.3 66.4 8.5 9.0 24.6 2.8 10.0 8.8 12.8 13.7 15.9 17.5 7.5 15.6 13.5 19.2 39.6 10.7 26.4 12.5 9.5 6.5 52.5 88.6 17.7 4.3 11.1 10.3 13.5 24.4 10.1 14.9 3.1 14.4 20.7 11.1 16.2 26.0 10.0 18.5 57.1 26.6 10.5 10.2 8.0 18.3 9.8 15.4 4.5 27.3 27.9 22.5 9.8 17.0 3.9 14.3 11.6 14.2 8.6 6.4 5.7 6.7 42.3 4.2 10.6 20.2 17.1 2.9 2.0 5.2 4.0 4.6 13.2 11.0 2.1 4.9 8.4 15.1 16.6 20.3 2.9 9.4 7.2 1.0 22.3 32.3 3.8 5.0 0.5 9.4 28.9 3.8 2.3 8.0 0.2 0.1 10.1 9.1 0.1 6.2 10.1 23.2 4.9 12.1 6.4 4.7 21.4 8.2 5.8 18.5 7.1 5.9 12.4 4.6 9.5 2.6 4.7 6.8 6.3 2.9 7.2 3.0 12.6 0.0 8.4 0.0 14.2 11.6 4.2 12.6 6.4 3.9 4.3 3.7 14.3 3.0 4.9 3.4 0.7 8.6 13.7 0.2 5.8 5.7 8.5 24.6 8.8 12.8 9.5 6.5 11.1 10.3 14.4 15.4 ALDH3B1 ALDH7 ENSG00000006534 "Aldehyde dehydrogenase 3 family member B1" P43353 11 68008578-68029282 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 39.8" "Cell line enhanced" "Detected in many" "A549: 44.5;CAPAN-2: 45.9;U-87 MG: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 39.8" "Group enriched" "Detected in many" 10 "dendritic cells: 17.6;granulocytes: 39.8;monocytes: 32.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038525 Uncertain "HPA038525: " "unprognostic (3.50e-1)" "unprognostic (4.22e-1)" "prognostic unfavourable (1.18e-4)" "unprognostic (1.56e-2)" "unprognostic (9.66e-3)" "unprognostic (9.73e-2)" "unprognostic (7.93e-3)" "unprognostic (2.62e-1)" "unprognostic (2.01e-1)" "unprognostic (1.06e-1)" "prognostic unfavourable (6.07e-4)" "unprognostic (8.27e-2)" "unprognostic (6.49e-3)" "unprognostic (1.00e-1)" "unprognostic (2.75e-2)" "unprognostic (6.69e-3)" "unprognostic (1.06e-1)" 9.1 9.8 1.8 5.0 2.5 21.4 2.4 1.3 2.3 6.2 7.8 4.2 1.1 11.8 4.0 7.0 4.0 21.0 13.7 3.1 2.6 2.4 9.3 5.1 28.5 14.3 4.3 1.4 6.6 12.9 0.0 3.8 13.4 3.8 4.6 3.1 7.8 5.7 2.0 2.0 1.8 21.4 4.2 5.6 11.7 10.4 2.9 1.9 0.7 1.7 1.5 3.3 7.6 3.8 0.1 17.6 39.8 32.9 2.9 0.1 9.8 3.2 44.5 0.3 0.9 3.0 9.6 8.1 4.5 7.5 3.3 1.6 1.6 45.9 0.2 8.1 10.5 3.8 0.1 0.6 0.8 0.1 0.3 0.4 17.9 3.9 18.9 2.6 0.1 6.9 2.0 1.6 4.4 0.1 0.1 8.1 5.2 2.7 0.2 2.5 0.3 2.7 1.0 1.7 24.5 5.3 0.4 0.5 0.2 10.5 8.8 4.4 10.2 5.8 5.0 4.7 6.7 22.9 1.5 0.1 0.8 0.0 27.1 7.3 2.1 11.8 23.0 39.8 0.0 32.9 0.1 0.1 0.0 0.0 17.6 0.1 0.0 0.0 6.9 2.9 29.1 1.8 0.0 9.8 1.8 2.5 1.3 2.3 2.6 2.4 4.3 1.4 3.8 1.9 ALDH3B2 ALDH8 ENSG00000132746 "Aldehyde dehydrogenase 3 family member B2" P48448 11 67662162-67681200 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "breast: 28.1;esophagus: 48.2;lymphoid tissue: 34.2;skin 1: 38.7" "Group enriched" "Detected in some" 5 "MCF7: 30.9;SK-BR-3: 32.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" HPA045132 Approved "HPA045132: AB_10795993" "unprognostic (2.25e-1)" "unprognostic (2.41e-1)" "unprognostic (1.65e-1)" "unprognostic (8.65e-2)" "unprognostic (2.13e-1)" "unprognostic (6.09e-2)" "unprognostic (3.12e-2)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-2)" "unprognostic (5.92e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 28.1 0.1 0.1 6.7 0.1 0.1 5.0 0.0 1.5 2.4 48.2 1.5 0.1 0.1 0.1 0.0 0.6 0.1 0.6 0.1 0.1 0.1 0.4 0.1 0.6 0.3 11.2 0.1 1.8 0.0 0.1 17.1 4.6 0.1 38.7 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.8 0.1 25.7 34.2 4.6 11.6 1.0 0.1 0.6 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 1.8 1.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 30.9 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.0 0.0 32.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902781 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 73.7;liver: 92.6" "Cell line enhanced" "Detected in many" "Hep G2: 33.9;SK-BR-3: 35.0" "Cancer enhanced" "Detected in all" "liver cancer: 72.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401" Enhanced 40000 "CAB004645: AB_425775, HPA006401: AB_1844731" "unprognostic (1.17e-1)" "prognostic favourable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-3)" "unprognostic (9.41e-3)" "unprognostic (3.83e-1)" "unprognostic (2.69e-3)" "unprognostic (9.34e-2)" 22.9 4.1 14.4 2.0 18.0 4.6 6.6 3.1 16.8 3.8 2.4 8.6 18.9 1.3 2.5 5.2 11.4 2.7 3.0 12.6 8.6 7.1 73.7 92.6 2.4 1.7 15.9 11.2 2.9 2.2 9.4 2.4 8.3 8.5 12.1 1.6 9.7 2.4 12.1 25.6 8.0 1.3 3.3 2.7 2.1 3.4 1.4 6.6 2.8 3.0 8.9 2.9 8.3 3.6 1.5 7.2 2.6 5.6 0.3 1.4 2.2 5.0 7.9 4.0 11.9 17.0 2.5 9.8 4.8 3.0 5.0 4.0 5.7 3.8 3.4 6.5 6.2 13.5 6.8 14.4 1.8 1.9 6.0 1.9 1.8 33.9 5.3 1.6 6.1 6.6 8.1 2.8 2.7 5.6 7.5 2.5 3.4 12.9 1.6 8.2 1.9 4.0 10.5 3.3 3.9 5.2 12.8 7.9 3.0 8.5 35.0 6.3 15.9 2.6 4.6 4.3 5.7 5.2 1.7 2.7 6.5 0.9 1.5 13.2 5.7 0.0 4.1 2.6 1.1 5.6 0.9 1.5 0.7 1.4 7.2 1.1 0.3 0.9 0.6 0.3 3.1 2.4 1.0 2.2 14.4 18.0 3.1 16.8 8.6 7.1 15.9 11.2 8.5 6.6 ALDH5A1 "SSADH, SSDH" ENSG00000112294 "Aldehyde dehydrogenase 5 family member A1" P51649 6 24494852-24537207 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 62.6" "Cell line enhanced" "Detected in many" "Daudi: 40.3;U-698: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029715, HPA029716" Enhanced Supported Mitochondria 44000 Mitochondria "HPA029715: AB_10599994, HPA029716: AB_10601876" "unprognostic (7.43e-2)" "unprognostic (1.12e-3)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "prognostic favourable (7.61e-6)" "unprognostic (2.38e-2)" "unprognostic (2.17e-2)" "prognostic favourable (6.20e-4)" "unprognostic (1.43e-2)" "unprognostic (1.21e-1)" "prognostic favourable (3.68e-4)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.00e-2)" "unprognostic (1.08e-2)" 5.8 4.8 23.7 8.3 27.4 3.1 4.1 13.5 21.5 4.1 6.0 9.5 1.2 7.7 3.9 3.1 5.6 13.5 4.4 9.8 17.3 21.0 18.4 62.6 5.0 8.9 16.0 14.7 5.8 6.6 11.4 4.5 2.2 13.0 6.2 5.7 4.1 3.9 4.3 31.1 6.9 5.4 2.8 10.9 4.8 5.2 3.7 8.8 21.4 12.1 4.9 8.8 6.3 5.5 3.9 3.8 0.4 0.2 1.6 6.8 1.2 3.2 2.9 2.1 3.1 0.0 0.0 3.5 0.3 0.6 0.8 0.5 11.5 0.8 40.3 6.1 0.3 0.0 3.4 0.4 0.5 4.1 5.6 6.3 1.9 13.1 0.5 9.7 0.8 0.3 1.6 0.1 0.0 0.0 3.1 0.0 0.6 7.5 11.8 5.8 0.8 1.5 13.6 0.6 0.3 2.4 6.4 3.6 3.2 3.8 0.4 3.9 5.7 5.3 0.0 0.4 2.0 0.1 2.0 5.7 8.5 50.3 0.0 3.1 0.4 0.4 0.1 0.2 1.7 0.0 3.3 3.7 2.4 2.8 0.2 3.9 6.8 5.7 0.4 1.6 0.2 3.8 1.6 1.2 23.7 27.4 13.5 21.5 17.3 21.0 16.0 14.7 13.0 8.8 ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056850-74084493 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 140.0;liver: 134.5" "Cell line enhanced" "Detected in all" "T-47d: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 25.5" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria 9100 Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favourable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favourable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" 14.1 6.9 31.3 2.8 30.9 2.3 6.7 11.6 26.4 8.0 11.0 20.1 4.6 11.0 5.5 5.5 5.0 6.2 4.8 15.6 21.1 14.2 140.0 134.5 4.7 3.0 19.4 18.5 12.3 11.8 16.4 3.2 4.0 14.8 11.0 7.2 7.1 7.8 7.8 10.5 3.4 9.3 5.6 13.1 3.1 9.6 7.4 18.7 2.0 12.1 4.0 3.1 6.3 3.3 4.5 5.6 25.5 3.8 5.5 6.7 2.8 4.6 4.0 5.7 12.1 20.8 10.2 9.2 3.2 6.1 3.5 6.0 9.0 5.2 5.4 7.2 6.9 2.7 12.9 3.6 7.7 4.8 1.8 2.5 4.2 9.9 23.7 1.3 1.2 15.0 6.5 4.5 11.4 6.1 4.0 7.5 2.4 17.7 3.7 2.0 4.5 2.7 7.6 5.9 7.1 5.6 3.5 2.3 3.6 10.7 11.6 2.8 29.6 4.8 1.9 4.0 4.9 6.2 1.2 5.1 9.1 5.5 5.2 1.6 3.8 13.3 3.8 25.5 4.5 2.9 6.7 4.5 5.1 5.3 5.6 3.6 6.5 4.6 1.5 5.5 2.4 3.2 3.6 2.8 31.3 30.9 11.6 26.4 21.1 14.2 19.4 18.5 14.8 18.7 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595418 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 64.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 9.7" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023296 Enhanced Supported Mitochondria,Cytosol 140000 Mitochondria Cytosol "HPA023296: AB_1844738" "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favourable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 9.0 14.2 46.0 3.4 39.1 0.8 18.8 11.0 22.5 14.0 11.5 23.1 7.2 9.5 10.5 7.5 13.5 11.9 7.8 10.8 35.0 17.3 46.5 64.4 6.4 3.1 28.7 18.5 27.6 10.8 17.7 5.9 17.7 16.9 17.6 11.2 13.7 15.0 12.2 4.5 11.9 8.1 9.8 20.2 2.8 9.0 4.9 28.4 4.0 19.4 10.1 7.4 7.2 7.1 1.3 9.7 0.7 0.3 0.1 1.8 0.6 14.8 9.8 27.8 46.0 23.2 13.8 35.5 17.8 22.0 20.7 26.8 27.6 14.3 0.0 18.2 13.9 11.1 8.6 60.2 19.1 0.0 10.4 2.8 14.7 23.4 11.3 0.0 0.0 16.9 14.2 16.1 11.6 16.5 0.0 0.0 18.2 9.7 0.6 0.0 18.8 8.3 8.9 31.6 0.0 19.7 11.3 9.5 11.3 0.0 9.8 10.3 17.7 0.6 20.0 6.0 18.6 6.9 12.2 0.0 0.0 0.0 3.2 0.0 9.6 0.7 0.3 0.1 0.2 0.0 0.3 1.3 0.3 0.2 2.7 1.1 1.8 1.0 0.3 0.1 0.0 9.7 0.1 0.6 46.0 39.1 11.0 22.5 35.0 17.3 28.7 18.5 16.9 28.4 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" 1100000 Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favourable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 39.1 52.7 30.8 17.4 25.4 7.7 39.6 16.2 26.6 20.3 18.0 22.7 17.1 19.5 15.5 35.5 47.0 18.8 22.2 22.2 24.8 21.1 50.5 73.5 20.7 20.4 23.7 18.4 20.6 17.8 31.2 19.2 14.1 22.8 24.6 18.7 27.2 52.2 23.2 29.9 22.6 23.9 19.2 21.9 18.8 14.7 37.3 21.5 12.4 45.1 24.2 27.9 18.5 19.1 29.6 20.2 29.4 24.5 23.1 39.0 24.4 17.4 17.1 16.0 14.3 51.2 45.1 13.4 23.2 32.9 23.3 20.3 10.6 13.2 0.0 22.2 20.7 13.8 12.9 22.6 27.7 8.1 16.4 11.1 12.3 11.5 26.4 17.5 11.9 28.9 11.5 24.7 20.8 20.2 17.6 15.8 36.3 10.5 11.6 18.0 23.3 21.1 10.0 20.4 23.4 30.3 16.6 19.0 13.1 16.5 18.6 21.2 35.5 26.6 19.9 14.1 13.8 17.2 11.7 14.7 19.2 17.5 15.9 16.7 13.5 26.8 20.3 28.1 28.3 21.5 30.1 29.6 27.7 30.6 20.2 26.0 28.1 32.0 29.4 23.1 24.5 12.6 39.0 24.4 30.8 25.4 16.2 26.6 24.8 21.1 23.7 18.4 22.8 21.5 AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361913 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favourable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" 13.0 39.6 14.3 15.6 20.1 3.8 15.2 22.5 20.7 14.1 19.8 10.5 25.3 19.2 11.1 16.0 8.9 10.7 11.4 30.4 15.4 19.7 50.4 21.3 9.7 6.7 19.1 9.0 11.8 20.7 27.0 10.1 13.1 16.3 23.8 14.4 10.6 20.1 35.4 31.0 6.7 16.0 10.4 15.2 7.7 17.7 6.1 12.1 9.1 17.5 11.8 8.9 10.2 10.5 8.7 5.8 16.1 4.6 9.9 10.0 5.3 4.5 4.4 6.3 3.2 7.8 8.4 9.7 4.1 5.2 3.2 3.7 2.5 5.9 5.4 4.3 4.3 6.7 9.3 5.2 4.6 41.3 7.9 3.6 4.9 14.8 5.9 5.3 3.8 7.0 6.6 2.6 8.9 3.9 5.1 8.1 3.7 4.4 7.2 11.9 7.8 6.5 4.3 5.0 9.2 14.0 2.4 6.4 4.6 6.1 14.7 7.7 2.7 3.5 4.0 3.2 4.0 4.7 3.9 9.3 7.8 1.8 5.1 4.3 2.1 15.2 4.6 16.1 6.9 3.2 7.9 7.8 7.6 10.0 4.2 8.7 9.6 8.8 7.1 9.9 2.1 5.8 9.3 5.3 14.3 20.1 22.5 20.7 15.4 19.7 19.1 9.0 16.3 12.1 CYB5D1 FLJ32499 ENSG00000182224 "Cytochrome b5 domain containing 1" Q6P9G0 17 7857746-7862282 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA021632 Uncertain Approved "Nucleoli,Golgi apparatus" "Nucleoli, Golgi apparatus" "HPA021632: AB_1847368" "unprognostic (1.99e-1)" "unprognostic (2.91e-1)" "unprognostic (1.23e-1)" "unprognostic (5.10e-3)" "unprognostic (2.34e-1)" "unprognostic (4.44e-3)" "unprognostic (1.12e-1)" "unprognostic (2.16e-2)" "unprognostic (1.34e-1)" "unprognostic (2.69e-2)" "unprognostic (2.89e-2)" "unprognostic (2.41e-2)" "unprognostic (1.04e-4)" "unprognostic (2.38e-2)" "unprognostic (1.25e-1)" "unprognostic (5.27e-3)" "unprognostic (1.79e-2)" 14.0 13.0 13.2 5.5 22.5 7.2 13.1 14.1 16.8 10.5 7.9 14.0 12.8 6.5 10.9 17.0 7.9 28.2 9.4 13.9 14.4 12.0 19.2 13.0 8.8 4.7 9.4 13.5 14.6 13.1 9.7 18.1 7.0 16.5 11.0 7.8 11.7 10.5 13.2 9.9 10.1 6.0 9.4 6.5 5.9 8.4 14.5 11.7 6.9 22.8 8.6 5.6 7.4 7.5 3.4 3.1 2.7 2.3 1.6 5.9 1.8 16.1 12.0 5.8 15.4 10.4 9.3 3.5 8.3 8.3 9.0 8.6 7.6 3.1 7.0 5.9 6.7 14.5 12.8 10.9 13.5 4.6 14.7 4.6 15.7 10.8 4.7 8.1 3.3 7.8 13.8 15.6 14.2 9.5 3.3 4.8 4.9 7.0 12.6 3.3 7.3 12.5 8.7 2.7 7.0 14.1 3.1 7.9 5.3 13.2 7.4 7.6 8.7 3.3 6.6 7.0 6.1 12.2 10.5 2.5 6.1 3.9 14.6 4.5 4.4 0.5 2.3 0.1 2.7 1.9 3.3 3.4 2.4 1.4 3.1 1.5 5.9 3.1 2.7 1.6 1.1 1.4 2.2 1.8 13.2 22.5 14.1 16.8 14.4 12.0 9.4 13.5 16.5 11.7 CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "liver: 802.4" "Cell line enhanced" "Detected in many" "HaCaT: 9.6;HL-60: 7.4;HMC-1: 7.9;NB-4: 20.2" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "MAIT T-cell: 3.9;myeloid DC: 9.1" "Group enriched" "Detected in many" 17 "dendritic cells: 9.1;T-cells: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced "Intracellular and membrane" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.6 0.3 0.1 0.1 0.2 0.7 0.0 0.1 0.3 0.8 0.2 1.3 0.1 0.1 0.1 0.3 802.4 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.1 0.1 0.3 0.1 0.0 0.2 0.1 1.1 0.1 0.6 0.1 0.1 0.1 0.4 0.1 0.3 0.1 0.1 0.2 0.2 1.5 0.1 0.1 0.0 9.1 0.0 0.3 0.2 3.9 0.3 0.1 0.0 0.3 0.9 3.2 1.8 0.6 1.4 3.9 0.0 0.3 0.0 2.3 1.2 0.2 0.4 9.6 0.0 0.2 0.3 0.2 1.3 1.5 0.1 1.1 0.5 7.4 7.9 0.9 0.2 0.0 0.6 0.0 0.4 0.3 0.9 0.6 0.5 20.2 5.5 0.3 0.3 5.4 0.0 1.7 0.0 0.0 0.0 3.7 0.0 0.6 0.2 0.8 0.0 1.2 0.4 2.0 0.9 2.0 0.8 2.7 1.3 6.3 0.1 0.0 0.0 0.0 0.1 0.0 3.9 0.0 1.7 1.0 9.1 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.0 0.3 0.1 0.2 0.6 0.3 0.1 0.1 0.1 0.1 0.3 0.1 GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703141 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HMC-1: 244.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" 1600000 "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: " "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (1.08e-2)" "unprognostic (3.96e-3)" "unprognostic (2.51e-1)" "prognostic unfavourable (5.21e-4)" "unprognostic (5.09e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (8.71e-2)" "unprognostic (1.20e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (6.21e-2)" 22.2 30.5 42.1 19.5 42.3 11.4 32.0 25.4 42.3 27.1 42.1 19.7 22.9 48.1 25.3 49.2 28.2 31.5 17.8 39.2 37.8 37.7 37.1 65.3 30.7 31.6 38.9 29.7 37.6 25.9 33.2 12.6 26.7 40.6 74.0 22.7 21.7 21.7 28.2 57.5 31.3 64.3 28.9 37.6 25.6 21.3 12.9 21.4 19.8 32.6 42.5 24.3 28.6 24.7 25.9 28.6 8.5 15.6 10.8 24.4 14.7 18.1 8.4 24.2 24.0 11.5 20.8 21.4 15.8 15.0 22.3 23.2 20.5 7.0 20.2 12.5 12.6 12.0 20.7 20.4 28.3 18.3 32.0 29.9 10.9 19.1 17.3 11.3 244.2 17.7 12.6 21.1 15.1 24.0 23.5 13.4 20.8 15.3 17.7 14.4 17.4 16.5 15.4 29.3 13.2 20.3 13.7 18.9 19.1 11.1 15.5 29.8 18.0 57.1 9.9 17.4 16.0 15.0 25.0 10.6 20.0 55.5 6.3 29.4 27.9 8.5 9.8 6.9 18.0 15.6 24.4 24.7 18.1 18.3 18.3 25.9 17.1 17.9 1.2 10.8 12.1 28.6 15.7 14.7 42.1 42.3 25.4 42.3 37.8 37.7 38.9 29.7 40.6 21.4 GLOD4 "C17orf25, CGI-150, HC71" ENSG00000167699 "Glyoxalase domain containing 4" Q9HC38 17 757097-783390 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021623, HPA023246, HPA023248" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol 3800000 Cytosol "Nucleoplasm, Nucleoli" "HPA021623: AB_1844365, HPA023246: AB_1844366, HPA023248: AB_1844367" "unprognostic (2.82e-1)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "unprognostic (1.45e-2)" "unprognostic (1.99e-1)" "unprognostic (2.11e-1)" "unprognostic (2.88e-1)" "unprognostic (3.35e-1)" "unprognostic (3.13e-2)" "unprognostic (6.27e-2)" "unprognostic (4.86e-2)" "unprognostic (1.96e-2)" "prognostic favourable (2.18e-6)" "unprognostic (6.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (3.02e-1)" 21.7 29.5 31.3 16.7 35.6 10.2 19.1 26.0 36.2 17.8 37.1 21.5 16.5 43.0 22.3 23.3 23.6 24.9 20.9 19.7 26.1 38.5 41.6 40.4 16.8 22.8 23.0 34.8 22.9 32.3 13.9 19.4 28.1 28.6 21.1 26.6 21.9 29.2 20.9 21.4 27.5 42.5 24.7 18.2 23.8 43.4 17.9 18.2 22.7 26.0 19.2 24.0 25.2 17.5 27.5 17.9 17.8 24.6 22.8 36.7 26.0 40.3 36.6 42.2 23.3 18.6 18.5 25.8 32.4 19.9 26.3 20.0 29.6 29.0 48.2 35.3 14.5 29.3 36.8 20.5 27.5 35.3 31.4 23.2 20.3 38.7 18.5 23.9 30.7 12.9 28.6 26.4 23.2 24.2 37.9 31.4 27.7 24.9 41.0 18.4 30.9 12.5 41.1 17.1 22.1 25.9 27.6 19.3 32.4 25.7 18.6 41.5 23.1 25.4 31.5 25.1 20.1 35.1 40.5 17.7 32.2 29.6 29.8 26.9 26.2 9.2 19.8 17.8 27.7 24.2 30.2 27.0 33.6 33.3 17.5 27.5 28.7 31.3 2.7 22.8 24.6 17.9 36.7 26.0 31.3 35.6 26.0 36.2 26.1 38.5 23.0 34.8 28.6 18.2 GRHPR "GLXR, PH2" ENSG00000137106 "Glyoxylate and hydroxypyruvate reductase" Q9UBQ7 9 37422666-37436990 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 172.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022971 Uncertain Approved Nucleoplasm,Cytosol 1400000 Cytosol Nucleoplasm "HPA022971: AB_1849975" "prognostic favourable (7.00e-5)" "unprognostic (6.84e-2)" "unprognostic (2.62e-1)" "unprognostic (2.64e-3)" "unprognostic (5.78e-3)" "unprognostic (3.04e-1)" "unprognostic (1.02e-3)" "unprognostic (1.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.49e-2)" "unprognostic (5.88e-2)" "unprognostic (2.36e-1)" "prognostic favourable (5.39e-9)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (1.79e-1)" 12.8 33.7 16.3 13.8 17.4 9.9 12.3 9.5 22.3 12.1 17.6 27.5 11.6 17.2 14.3 18.1 17.6 12.9 18.1 29.2 15.8 14.7 41.9 172.0 9.7 13.8 20.0 16.5 17.0 15.5 9.5 8.8 13.2 15.5 14.2 10.2 13.5 21.6 14.0 40.0 14.8 14.6 14.2 19.4 10.0 13.3 13.0 18.7 9.5 15.1 25.2 13.6 13.4 11.7 30.6 33.2 17.8 30.3 28.9 25.9 22.4 31.3 45.2 25.6 23.4 23.6 26.2 26.0 25.1 33.3 34.2 37.2 17.1 13.6 30.1 14.8 29.4 14.2 14.7 32.7 20.5 40.2 18.4 17.6 42.1 30.3 37.3 16.7 18.3 31.3 28.7 19.8 25.5 29.6 32.2 12.4 30.0 24.0 16.3 17.2 15.6 19.7 16.1 18.8 16.7 45.6 17.8 10.7 19.2 21.6 41.2 23.4 23.2 21.6 32.2 18.8 30.2 13.0 21.6 9.8 7.6 20.1 26.7 9.6 27.5 17.8 30.2 15.0 19.4 30.3 16.2 28.6 20.7 22.0 33.2 30.6 20.4 17.3 7.0 28.9 24.7 29.8 25.9 22.4 16.3 17.4 9.5 22.3 15.8 14.7 20.0 16.5 15.5 18.7 HAGH "GLO2, GLXII, HAGH1" ENSG00000063854 "Hydroxyacylglutathione hydrolase" Q16775 16 1795620-1827194 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 91.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043041, HPA061143" Approved 3000000 "HPA043041: , HPA061143: " "unprognostic (3.11e-1)" "prognostic favourable (5.82e-5)" "unprognostic (2.54e-1)" "unprognostic (1.93e-2)" "unprognostic (5.84e-2)" "unprognostic (1.54e-1)" "prognostic favourable (5.33e-6)" "unprognostic (5.78e-3)" "unprognostic (3.34e-2)" "unprognostic (7.69e-2)" "unprognostic (3.34e-3)" "unprognostic (1.60e-1)" "prognostic favourable (1.81e-6)" "unprognostic (1.20e-1)" "unprognostic (6.24e-2)" "unprognostic (7.18e-3)" "prognostic favourable (5.19e-4)" 14.8 36.9 24.9 7.8 26.7 26.2 16.4 26.8 35.3 9.7 12.9 13.6 19.6 17.6 6.8 13.0 11.7 11.8 9.9 50.9 28.0 24.5 38.8 91.4 14.5 8.5 23.2 24.5 6.3 24.6 17.1 19.7 9.2 18.5 12.4 9.5 11.9 12.5 16.2 67.1 11.0 17.1 11.7 20.7 10.1 13.1 33.8 13.7 7.4 14.1 18.3 7.2 9.7 18.2 13.7 28.9 27.7 36.5 10.9 18.3 12.5 11.4 17.4 15.8 17.8 13.8 5.5 14.2 14.4 13.4 22.3 18.0 8.9 10.0 2.4 29.7 12.3 12.6 14.9 14.4 6.7 23.8 24.0 4.4 17.8 25.5 19.9 5.8 24.2 6.7 31.1 11.1 7.6 19.1 5.8 21.6 7.0 18.9 14.9 12.5 6.0 16.1 12.6 9.9 27.0 28.6 5.2 21.2 18.3 15.8 20.3 31.0 14.9 19.4 14.5 6.8 8.4 14.2 16.5 24.5 23.1 7.1 11.6 5.4 10.8 14.4 15.3 27.7 12.6 25.8 9.2 13.7 16.2 12.9 13.7 12.4 15.8 13.2 13.5 10.9 36.5 28.9 18.3 12.5 24.9 26.7 26.8 35.3 28.0 24.5 23.2 24.5 18.5 13.7 HAGHL MGC2605 ENSG00000103253 "Hydroxyacylglutathione hydrolase like" Q6PII5 16 726936-735525 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7" "Cell line enhanced" "Detected in many" "RPMI-8226: 29.4;U-266/70: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074402 Approved "HPA074402: " "unprognostic (6.74e-2)" "unprognostic (1.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.60e-2)" "unprognostic (1.49e-1)" "unprognostic (4.56e-2)" "unprognostic (5.62e-3)" "unprognostic (9.52e-2)" "unprognostic (2.16e-1)" "unprognostic (1.83e-2)" "unprognostic (6.37e-2)" "unprognostic (1.77e-1)" "prognostic favourable (1.18e-5)" "unprognostic (1.92e-2)" "unprognostic (5.36e-1)" "unprognostic (3.41e-2)" "unprognostic (2.41e-1)" 2.7 8.7 10.0 6.2 19.7 4.5 1.2 13.0 15.5 1.7 2.1 9.4 2.5 2.9 3.7 2.7 1.1 7.9 2.6 5.3 10.6 10.9 4.9 1.4 4.0 8.3 15.9 6.7 1.4 2.4 5.8 8.1 2.3 10.7 2.6 0.9 4.5 9.6 4.0 1.3 2.7 4.5 1.1 13.9 8.4 5.8 3.5 9.1 2.9 0.9 1.6 3.8 1.8 1.0 13.1 3.7 1.3 1.5 8.5 7.2 3.1 2.1 2.3 0.5 3.0 0.5 1.1 2.3 1.9 1.3 0.4 0.5 1.0 3.0 4.8 2.9 0.1 2.9 0.5 0.7 0.0 14.0 2.0 1.5 5.3 1.8 3.6 6.0 4.5 2.1 0.7 0.0 1.0 0.3 2.8 4.3 0.6 14.4 0.1 8.4 3.3 5.0 3.1 1.4 29.4 1.2 0.7 11.1 6.6 1.0 8.6 9.1 5.4 10.5 1.9 2.3 3.6 0.8 1.2 31.5 4.0 6.6 3.7 6.0 4.2 0.0 1.5 1.3 6.2 0.5 7.2 13.1 4.1 6.8 1.9 3.5 1.2 4.6 0.0 8.5 0.2 3.7 4.7 3.1 10.0 19.7 13.0 14.1 10.6 10.9 15.9 6.7 10.7 9.1 LDHA ENSG00000134333 "Lactate dehydrogenase A" P00338 11 18394388-18408425 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease mutation, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 249.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015336, CAB069404" Uncertain Supported Vesicles,Cytosol 300000000 Cytosol Vesicles "CAB015336: AB_2134947, CAB069404: " "unprognostic (8.83e-2)" "prognostic unfavourable (2.78e-5)" "unprognostic (3.81e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (4.66e-3)" "prognostic unfavourable (3.26e-8)" "prognostic unfavourable (2.27e-6)" "unprognostic (1.08e-1)" "unprognostic (1.88e-2)" "prognostic unfavourable (8.09e-6)" "unprognostic (1.76e-2)" "prognostic unfavourable (9.69e-9)" "unprognostic (4.15e-2)" "unprognostic (1.89e-1)" "unprognostic (3.07e-1)" "unprognostic (1.05e-2)" 84.2 56.4 24.5 52.6 32.5 64.0 56.0 22.3 40.2 38.1 53.5 13.5 9.1 60.5 24.9 36.2 77.7 29.0 31.6 59.4 24.4 33.0 100.1 249.1 37.1 59.4 29.7 25.7 49.7 34.1 10.5 16.4 49.7 44.3 33.3 51.2 45.9 46.3 37.0 199.6 70.2 128.3 50.7 35.5 45.0 31.2 25.9 23.9 45.0 56.4 90.6 60.1 81.9 44.8 27.6 76.5 29.1 61.2 32.8 52.2 72.1 131.7 82.0 3.1 46.2 72.2 49.3 44.0 127.5 135.5 112.0 166.7 36.6 21.7 99.7 41.9 128.8 106.6 82.0 195.4 242.9 34.0 48.5 34.5 74.9 62.8 17.8 85.1 25.9 49.2 90.1 44.0 44.1 66.1 48.6 48.0 131.1 34.9 70.0 53.9 19.8 102.6 45.4 32.7 83.5 178.0 30.6 24.6 30.4 69.1 57.0 23.6 26.8 20.3 59.5 140.3 50.9 122.1 1.5 38.2 55.9 95.9 200.8 44.1 47.2 28.9 53.1 29.1 38.1 61.2 42.6 27.6 50.2 40.1 76.5 19.2 32.8 33.3 18.1 32.8 59.5 25.8 52.2 72.1 24.5 32.5 22.3 40.2 24.4 33.0 29.7 25.7 44.3 23.9 LDHAL6A "LDH6A, MGC23940" ENSG00000166800 "Lactate dehydrogenase A like 6A" Q6ZMR3 11 18455824-18479600 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 18.9" "Cell line enriched" "Detected in some" 6 "HL-60: 15.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "unprognostic (1.41e-1)" "unprognostic (4.84e-2)" "unprognostic (8.95e-2)" "unprognostic (5.35e-2)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" "unprognostic (7.34e-2)" "unprognostic (1.75e-1)" "unprognostic (1.23e-1)" "unprognostic (1.60e-1)" "unprognostic (2.35e-2)" "unprognostic (3.58e-1)" "unprognostic (2.22e-2)" "unprognostic (2.51e-1)" "unprognostic (1.81e-1)" "unprognostic (8.31e-3)" "unprognostic (1.48e-1)" 0.2 0.7 0.6 0.4 0.6 1.4 0.2 2.4 1.9 0.1 0.2 0.4 0.0 0.9 0.2 0.4 0.4 0.2 0.3 1.1 0.4 0.5 0.4 0.2 0.2 0.6 0.3 0.7 0.7 0.4 0.0 0.4 0.2 2.2 0.2 0.1 1.9 0.3 0.3 0.2 1.5 0.8 0.0 0.3 0.4 0.4 18.9 0.0 0.1 0.8 0.0 0.1 0.2 0.2 1.3 0.7 3.5 0.5 1.6 1.9 0.2 0.2 0.4 1.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.5 0.5 0.8 0.2 0.0 0.6 0.1 0.3 0.4 0.7 0.9 0.6 0.8 0.5 0.0 15.3 0.7 0.1 0.2 0.0 0.2 0.0 0.4 1.2 0.1 0.2 0.4 1.1 0.3 0.7 0.7 0.4 1.5 0.1 1.1 0.6 0.5 0.5 0.3 0.2 0.4 2.2 0.8 0.5 0.2 1.0 0.3 2.7 0.5 0.2 0.3 0.6 0.3 2.1 0.4 0.4 1.9 0.3 0.3 0.9 0.5 0.5 0.7 1.3 1.1 1.0 3.5 1.6 0.5 0.5 1.3 0.2 0.6 0.6 2.4 1.9 0.4 0.5 0.3 0.7 2.2 0.0 LDHAL6B "LDH6B, LDHAL6, LDHL" ENSG00000171989 "Lactate dehydrogenase A like 6B" Q9BYZ2 15 59206823-59208515 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "testis: 56.6" "Cell line enhanced" "Detected in some" "A549: 1.1;CAPAN-2: 1.5;HaCaT: 1.6;HeLa: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "olfactory region: 1.7" HPA053962 Enhanced "HPA053962: " "unprognostic (1.59e-1)" "unprognostic (9.41e-2)" "unprognostic (2.37e-1)" "unprognostic (4.46e-2)" "unprognostic (6.59e-2)" "unprognostic (2.23e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-1)" "unprognostic (2.29e-1)" "unprognostic (1.66e-1)" "unprognostic (5.13e-3)" "unprognostic (1.64e-1)" "unprognostic (3.12e-7)" "unprognostic (3.47e-2)" "unprognostic (1.49e-2)" "unprognostic (8.53e-2)" "unprognostic (7.80e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.8 0.0 0.4 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 1.5 0.4 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.4 0.4 0.7 0.3 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 LDHB ENSG00000111716 "Lactate dehydrogenase B" P07195 12 21635342-21757857 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 255.8;kidney: 233.1" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 318.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "T-cells: 145.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004641, HPA019007" Enhanced Supported Cytosol 780000000 Cytosol "CAB004641: AB_425525, HPA019007: " "unprognostic (2.93e-1)" "unprognostic (9.20e-3)" "unprognostic (6.10e-2)" "unprognostic (1.11e-1)" "unprognostic (5.39e-3)" "unprognostic (1.36e-3)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (5.34e-2)" "unprognostic (8.40e-2)" "unprognostic (2.91e-1)" "unprognostic (6.41e-2)" "prognostic favourable (2.51e-4)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (2.55e-1)" "unprognostic (9.32e-2)" 70.9 60.2 79.5 33.3 79.6 40.8 33.4 52.4 80.1 24.9 31.8 30.6 13.2 11.8 38.7 27.3 25.6 34.4 32.3 255.8 58.8 69.9 233.1 9.8 27.7 52.3 91.6 62.3 68.0 54.8 41.8 19.4 40.1 84.9 34.9 39.4 26.8 21.8 42.2 29.7 8.6 18.0 42.9 52.9 23.8 47.5 16.4 47.6 59.1 48.5 56.3 58.7 49.7 21.8 28.1 32.9 33.0 15.3 33.7 145.1 93.2 32.7 88.0 77.4 50.9 55.5 61.8 90.0 45.8 45.8 64.1 63.5 139.3 0.1 116.1 30.1 30.8 16.5 106.4 84.9 81.7 29.7 74.1 119.5 84.1 0.1 53.1 111.5 51.7 70.6 30.4 56.1 76.4 73.1 65.3 17.5 70.5 0.1 94.7 135.0 223.2 38.2 85.6 108.0 93.6 318.2 146.3 24.9 57.7 21.0 32.6 79.0 0.2 87.5 28.4 43.2 56.7 30.7 86.3 15.5 20.9 152.5 47.9 53.4 51.2 33.0 15.3 1.8 28.5 9.4 47.5 28.1 110.7 59.4 28.3 17.7 145.1 92.2 2.5 33.7 6.7 32.9 105.4 93.2 79.5 79.6 52.4 80.1 58.8 69.9 91.6 62.3 84.9 47.6 LDHC CT32 ENSG00000166796 "Lactate dehydrogenase C" P07864 11 18412307-18452058 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "testis: 143.9" "Cell line enhanced" "Detected in some" "U-2197: 8.5;U-266/70: 7.6;U-266/84: 6.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045442 Enhanced "HPA045442: AB_10966720" "unprognostic (2.32e-2)" "unprognostic (3.42e-3)" "unprognostic (1.87e-1)" "unprognostic (2.83e-2)" "unprognostic (2.19e-1)" "unprognostic (8.56e-4)" "unprognostic (1.35e-1)" "unprognostic (5.74e-2)" "unprognostic (6.65e-2)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (1.18e-2)" "unprognostic (1.08e-1)" "unprognostic (9.30e-2)" "unprognostic (3.00e-1)" "unprognostic (4.25e-1)" "unprognostic (1.93e-1)" 0.1 0.1 0.7 0.0 0.9 0.1 0.1 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.1 0.0 0.5 0.2 0.1 0.1 0.4 0.0 0.1 0.3 0.0 0.1 0.4 0.0 0.3 0.0 0.4 0.1 0.0 0.2 0.1 0.0 0.2 0.1 0.3 0.0 0.3 0.0 0.0 143.9 0.3 0.0 0.2 0.1 0.2 0.0 0.0 2.4 2.7 3.6 1.1 0.2 3.8 1.2 0.0 0.0 0.3 1.9 1.4 1.6 1.9 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.1 0.4 0.2 0.0 0.0 0.1 0.2 2.7 0.2 1.0 0.0 0.0 0.2 0.3 0.0 0.4 0.1 0.1 1.0 0.1 0.6 0.0 0.4 0.2 0.5 0.0 0.5 0.1 0.0 0.1 0.0 0.0 1.9 0.0 2.2 3.4 0.5 0.2 0.1 0.8 0.3 2.7 8.5 0.1 7.6 6.7 0.3 0.1 0.0 0.1 1.3 0.7 1.0 0.6 1.0 2.3 0.8 1.8 2.2 0.0 2.4 3.8 2.6 3.6 0.2 1.1 2.7 1.7 1.2 0.7 0.9 0.6 0.4 0.2 0.1 0.3 0.0 0.4 0.3 LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116771 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.3;skeletal muscle: 39.7" "Cell line enhanced" "Detected in many" "Hep G2: 8.5;HMC-1: 11.8;T-47d: 22.9;U-266/70: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 8.9;classical monocyte: 2.7;intermediate monocyte: 4.6;non-classical monocyte: 5.7" "Group enriched" "Detected in many" 31 "granulocytes: 8.9;monocytes: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Cytosol Cytosol "HPA041766: , HPA048639: , HPA066148: " "unprognostic (8.75e-2)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "prognostic favourable (5.61e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-1)" "prognostic favourable (2.95e-14)" "unprognostic (4.10e-3)" "unprognostic (4.49e-2)" "unprognostic (7.00e-2)" "unprognostic (2.20e-1)" 15.3 5.5 6.8 1.6 6.7 0.8 3.7 4.9 11.7 4.1 12.5 7.6 4.5 6.1 1.5 3.0 3.8 2.1 3.6 25.3 6.6 5.8 21.5 44.3 2.8 0.9 8.1 9.7 7.9 7.7 8.5 4.4 2.1 9.9 4.4 6.8 5.1 14.2 4.5 39.7 1.8 2.5 1.2 4.5 0.7 11.2 1.0 4.0 0.0 4.3 14.4 2.7 1.1 1.2 0.0 0.2 8.9 5.7 0.1 0.1 0.9 0.5 1.6 0.0 0.3 1.3 1.1 5.0 0.1 0.1 0.1 0.2 2.1 2.1 0.0 1.7 0.7 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.5 8.5 2.1 0.0 11.8 1.6 0.2 0.0 0.0 0.1 0.6 1.9 0.0 3.9 0.0 0.6 1.1 1.0 0.0 0.0 5.9 1.1 0.1 0.0 0.0 0.0 4.0 0.2 22.9 2.5 0.0 0.0 0.2 0.0 0.0 9.1 0.5 0.0 1.5 0.0 0.0 8.9 2.7 0.8 0.0 4.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 5.7 0.0 0.0 0.9 6.8 6.7 4.9 11.7 6.6 5.8 8.1 9.7 9.9 4.0 ME1 ENSG00000065833 "Malic enzyme 1" P48163 6 83210389-83431071 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 8 "MAIT T-cell: 15.6" "Lineage enriched" "Detected in many" 11 "T-cells: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006493 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" 3800000 "Nucleoplasm, Plasma membrane" Cytosol "HPA006493: AB_1078272" "unprognostic (7.21e-2)" "unprognostic (3.99e-2)" "unprognostic (2.24e-1)" "unprognostic (3.12e-3)" "prognostic unfavourable (7.73e-4)" "unprognostic (7.98e-3)" "prognostic unfavourable (4.57e-5)" "unprognostic (3.24e-1)" "unprognostic (4.44e-3)" "unprognostic (1.41e-3)" "unprognostic (7.10e-3)" "unprognostic (2.43e-1)" "prognostic unfavourable (1.81e-7)" "unprognostic (4.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-2)" "unprognostic (4.51e-2)" 30.7 35.3 16.3 4.6 17.7 0.8 27.1 5.5 13.1 5.9 6.7 5.4 39.2 18.1 3.8 7.4 24.5 4.2 13.5 21.3 10.5 14.0 3.6 12.4 7.7 6.0 16.8 11.8 10.0 3.3 30.0 11.1 2.9 16.3 7.9 10.1 9.3 7.8 30.2 25.7 10.1 8.7 18.7 17.2 6.3 20.0 13.4 7.2 1.4 6.3 20.9 4.5 13.7 14.9 0.0 0.0 0.0 1.4 0.0 15.6 0.5 9.5 19.8 0.4 0.0 16.9 15.8 0.0 6.2 15.9 6.6 12.9 46.4 8.4 0.0 16.2 14.5 10.1 14.7 5.5 7.3 0.0 8.3 0.0 12.7 0.0 21.7 4.6 17.4 17.2 11.1 13.3 9.1 10.3 6.6 0.0 8.9 10.7 0.0 5.3 0.0 7.8 0.0 16.7 9.2 19.6 4.6 2.0 5.1 10.5 15.6 0.3 0.0 11.4 10.9 4.1 4.9 1.3 0.0 3.7 4.2 0.0 0.0 0.0 12.1 0.0 1.4 0.0 0.8 0.3 15.6 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 16.3 17.7 5.5 13.1 10.5 14.0 16.8 11.8 16.3 7.2 ME2 ENSG00000082212 "Malic enzyme 2" P23368 18 50878734-50954257 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008247, HPA008880" Enhanced Supported Mitochondria 3400000 Mitochondria "HPA008247: AB_1853704, HPA008880: AB_1853702" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (9.57e-3)" "unprognostic (2.22e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "prognostic unfavourable (8.29e-8)" "unprognostic (1.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-2)" "unprognostic (4.75e-2)" "unprognostic (1.43e-2)" "unprognostic (4.27e-3)" "unprognostic (2.30e-1)" "unprognostic (2.47e-1)" "unprognostic (4.09e-1)" 12.6 18.1 17.1 18.4 16.2 11.6 10.7 13.2 16.0 9.4 26.4 14.3 16.8 30.2 10.5 7.7 10.6 9.3 10.5 34.6 15.8 17.8 12.1 12.1 10.3 24.1 18.7 14.0 11.1 16.7 20.6 20.2 10.5 47.7 11.8 26.6 9.4 8.8 23.1 29.5 7.1 44.8 16.9 18.9 36.6 20.3 15.3 8.7 24.3 9.0 7.8 17.3 14.2 15.7 4.9 9.6 14.3 17.4 6.7 6.0 4.5 12.9 13.0 17.4 20.2 7.9 8.8 8.0 10.8 8.1 14.2 12.0 5.9 7.1 46.2 4.3 9.6 10.8 25.8 10.9 16.3 19.1 4.0 11.8 8.2 6.9 23.4 39.2 14.2 5.4 13.5 17.8 29.0 18.1 12.5 11.3 9.6 2.7 28.3 3.9 11.6 5.3 18.6 8.6 13.3 15.4 2.8 21.5 11.4 10.1 6.2 10.8 4.7 19.0 11.1 10.1 11.3 5.2 14.3 21.1 8.5 22.7 10.2 28.0 10.7 5.0 11.6 14.3 5.0 13.1 4.1 4.9 3.3 6.0 9.6 4.9 2.9 3.5 13.3 6.7 17.4 3.2 3.1 4.5 17.1 16.2 13.2 16.0 15.8 17.8 18.7 14.0 47.7 8.7 ME3 ENSG00000151376 "Malic enzyme 3" Q16798 11 86441108-86672636 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 26.9;HUVEC TERT2: 17.9;TIME: 19.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 5.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038473 Approved "HPA038473: AB_10672747" "unprognostic (1.83e-3)" "unprognostic (8.00e-2)" "unprognostic (1.99e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-1)" "unprognostic (2.91e-1)" "unprognostic (5.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-1)" "unprognostic (1.20e-1)" "unprognostic (5.74e-2)" "unprognostic (2.97e-1)" "unprognostic (1.65e-1)" "unprognostic (2.73e-1)" "unprognostic (2.96e-2)" "prognostic favourable (3.86e-4)" 17.2 15.9 16.0 6.3 27.7 5.8 13.1 15.7 26.1 19.3 14.3 4.8 7.3 7.8 15.8 7.6 5.0 9.0 12.9 21.9 12.2 13.1 12.6 3.9 8.1 4.3 12.5 18.1 22.1 16.7 28.5 15.4 5.4 20.2 13.0 15.0 11.5 13.6 10.3 21.2 3.0 7.1 15.6 5.5 7.3 20.8 8.8 8.4 2.8 8.2 6.3 2.9 10.3 10.2 0.0 5.0 0.0 0.9 2.2 3.1 1.0 0.0 9.0 2.5 0.0 4.1 8.5 0.0 3.1 4.7 6.4 8.1 6.8 26.9 0.0 2.7 2.8 0.1 0.0 0.0 2.9 4.7 0.0 4.6 7.4 0.0 6.1 0.5 0.0 5.9 1.4 5.1 0.0 17.9 0.1 0.0 4.2 0.9 1.2 0.0 0.6 3.7 3.9 0.0 0.3 5.7 10.5 3.1 0.0 1.9 0.0 0.0 0.4 0.7 19.8 0.8 0.6 13.3 0.4 0.0 1.6 0.0 0.7 8.3 0.8 0.0 0.9 0.0 1.9 0.1 0.0 0.0 1.9 3.1 5.0 0.0 2.3 2.7 0.0 2.2 0.3 0.6 0.0 1.0 16.0 27.7 15.7 26.1 12.2 13.1 12.5 18.1 20.2 8.4 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848233-66958376 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 41.1;liver: 76.0" "Cell line enhanced" "Detected in many" "HeLa: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 3.8;T-cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria 96000 Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavourable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favourable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 41.1 10.7 11.1 2.8 14.6 3.1 12.9 13.1 14.9 2.4 3.8 10.7 21.4 5.6 2.1 2.4 5.0 2.7 2.9 4.0 11.3 8.9 18.7 76.0 2.1 1.6 15.5 11.5 4.4 4.3 19.4 4.0 4.1 10.9 5.4 3.1 3.4 24.2 24.4 5.7 2.8 6.7 1.8 9.4 1.5 3.3 6.1 13.1 0.6 4.2 2.5 2.5 2.2 2.1 0.6 2.6 0.0 3.8 0.3 2.9 2.0 2.9 8.9 3.3 8.1 13.7 5.4 3.5 1.8 7.8 3.5 3.4 4.4 3.2 0.0 3.7 2.9 3.8 3.7 20.6 1.0 1.7 5.2 4.4 27.7 17.0 10.7 0.0 5.7 20.6 5.3 2.8 6.4 2.9 8.4 0.0 1.2 19.0 5.0 2.4 6.3 7.4 3.7 6.9 1.8 3.2 0.9 7.2 10.2 17.3 9.2 7.0 7.5 1.2 3.2 3.9 3.6 4.6 2.0 1.9 2.2 0.0 4.0 2.8 3.3 0.0 3.8 0.0 1.2 0.9 1.4 0.2 0.5 1.9 2.6 0.6 2.9 1.6 0.0 0.3 0.5 1.0 1.5 2.0 11.1 14.6 13.1 13.6 11.3 8.9 15.5 11.5 10.9 13.1 PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568112 "Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 419.5" "Cell line enriched" "Detected in some" 10 "ASC diff: 21.5" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA006277, HPA006507, CAB017027" Approved 380000 "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favourable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" 10.0 0.1 0.4 2.2 0.4 0.0 11.1 0.2 0.6 0.1 52.0 0.2 0.1 19.2 0.1 0.7 0.2 0.1 5.6 0.4 0.3 0.2 72.0 419.5 0.2 0.3 0.2 0.2 0.4 0.2 0.0 5.0 0.1 0.5 0.2 14.0 0.2 0.2 0.1 0.3 0.1 58.5 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.4 0.4 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.6 0.3 0.2 0.2 0.2 0.5 0.2 PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "intestine: 156.3;liver: 115.1" "Cell line enhanced" "Detected in many" "HHSteC: 34.9;hTCEpi: 33.9;SK-MEL-30: 32.1" "Cancer enhanced" "Detected in all" "liver cancer: 91.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria 3300000 Mitochondria "CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (3.11e-1)" "unprognostic (2.10e-1)" "prognostic favourable (2.81e-4)" "unprognostic (3.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-1)" "unprognostic (3.71e-1)" "unprognostic (2.82e-2)" "unprognostic (1.17e-1)" 8.2 2.5 1.0 4.9 1.9 1.0 4.3 1.3 1.3 1.3 69.7 1.4 6.9 51.8 1.3 8.5 4.5 1.2 4.2 2.6 1.5 1.0 26.4 115.1 6.0 4.4 1.7 1.2 1.8 8.5 3.4 1.7 1.2 1.8 2.0 5.4 1.9 11.5 4.9 1.0 2.7 156.3 1.1 1.7 6.7 3.3 3.9 1.3 1.3 5.8 1.9 4.6 2.8 1.9 8.8 10.8 2.4 15.1 1.5 6.5 3.9 5.4 3.1 0.9 5.8 3.6 3.7 14.8 6.8 8.2 5.7 9.3 5.1 6.3 13.9 0.8 10.5 8.0 6.0 8.8 4.7 7.1 0.2 2.5 1.7 27.2 34.9 4.8 11.0 4.3 33.9 3.6 8.8 4.6 7.1 25.8 2.2 23.7 1.2 2.4 1.0 4.1 2.8 3.4 7.9 1.7 8.5 3.7 5.9 5.2 6.8 32.1 9.1 7.5 0.8 1.2 6.6 1.8 1.9 17.7 5.5 3.4 3.5 7.7 3.0 0.1 8.2 2.4 3.1 15.1 3.4 8.8 3.5 3.5 10.8 6.1 2.2 2.0 1.0 1.5 14.4 1.9 6.5 3.9 1.0 1.9 1.3 1.3 1.5 1.0 1.7 1.2 1.8 1.3 PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301434 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 17.2;kidney: 12.4;liver: 47.8" "Cell line enriched" "Detected in some" 9 "K-562: 47.4" "Cancer enriched" "Detected in some" 9 "liver cancer: 56.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.7" "Low region specificity" "Detected in some" "HPA006653, CAB034376, CAB034378" Enhanced Approved "Golgi apparatus,Cytosol" 2900000 "Golgi apparatus, Cytosol" "CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: " "unprognostic (9.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.62e-1)" "unprognostic (7.86e-4)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-1)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (6.21e-3)" 0.1 0.0 0.1 0.3 0.1 7.2 0.1 0.9 0.2 0.1 4.9 0.1 0.1 5.8 0.1 1.3 0.1 0.0 0.7 0.1 0.1 0.4 12.4 47.8 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.6 17.2 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.2 0.1 0.4 0.1 0.1 0.1 0.1 PKM "OIP3, PK3, PKM2, THBP1" ENSG00000067225 "Pyruvate kinase M1/2" P14618 15 72199029-72231822 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 541.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019421, HPA029501" Uncertain Enhanced Cytosol 540000000 Cytosol "CAB019421: AB_2252325, HPA029501: AB_10602118" "unprognostic (8.73e-3)" "unprognostic (4.63e-3)" "unprognostic (1.68e-2)" "unprognostic (3.09e-1)" "unprognostic (6.51e-2)" "prognostic unfavourable (1.30e-4)" "prognostic unfavourable (2.74e-6)" "prognostic unfavourable (2.85e-4)" "unprognostic (9.51e-2)" "unprognostic (1.17e-2)" "prognostic unfavourable (5.17e-5)" "unprognostic (3.16e-1)" "unprognostic (3.22e-1)" "unprognostic (7.85e-2)" "unprognostic (3.17e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-2)" 23.2 76.8 53.8 49.8 70.4 57.5 41.6 56.6 85.9 65.7 31.2 32.1 31.5 26.4 24.7 41.8 76.4 37.9 32.9 94.8 50.1 57.1 60.9 6.1 33.3 39.4 62.5 63.6 26.2 15.6 33.3 28.3 27.1 80.5 34.8 31.9 54.4 47.1 47.5 541.2 51.8 25.1 44.7 34.9 30.7 26.7 29.0 29.4 23.5 23.8 114.4 60.6 53.1 40.9 25.1 79.6 14.9 90.6 11.6 37.4 114.9 81.5 209.8 42.3 50.0 50.9 57.2 35.0 88.5 206.7 142.1 143.9 59.0 100.5 62.1 89.6 165.6 118.9 133.7 180.0 111.4 109.0 63.2 38.0 105.5 48.8 35.5 49.3 82.0 51.9 83.9 109.5 45.0 83.6 9.5 49.8 224.1 50.7 18.4 21.2 52.3 80.1 54.7 135.4 118.3 188.7 105.0 44.0 48.0 115.4 71.2 90.5 49.9 35.9 65.1 161.9 88.6 158.2 160.5 64.0 90.4 54.7 199.3 81.6 158.6 12.6 90.6 14.9 23.5 52.6 22.8 25.1 31.3 23.2 79.6 16.1 27.3 20.2 11.8 11.6 40.2 16.2 37.4 114.9 53.8 70.4 56.6 85.9 50.1 57.1 62.5 63.6 80.5 29.4 RWDD2A "dJ747H23.2, MGC13523, RWDD2" ENSG00000013392 "RWD domain containing 2A" Q9UIY3 6 83193379-83198932 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030105, HPA030106, HPA030107" Uncertain Approved Vesicles Vesicles "HPA030105: AB_10599826, HPA030106: AB_10600896, HPA030107: AB_10601009" "unprognostic (2.51e-3)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (1.33e-1)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "prognostic favourable (3.82e-5)" "prognostic favourable (1.38e-4)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.57e-2)" "unprognostic (1.85e-3)" "unprognostic (2.59e-2)" 5.0 10.1 8.5 3.4 10.4 1.0 5.4 11.8 14.6 5.6 4.0 5.9 11.6 4.2 5.7 15.9 3.1 6.5 7.6 7.2 9.4 11.0 7.5 8.1 4.8 3.9 6.5 11.7 7.0 13.4 7.4 9.8 4.2 11.6 19.2 4.3 3.7 16.4 11.3 4.1 3.4 4.0 5.5 4.8 4.1 5.3 14.5 3.9 1.7 10.4 3.1 4.4 5.2 2.8 3.7 6.8 0.7 3.9 0.8 4.6 2.1 2.3 2.1 4.9 9.2 6.0 4.3 3.4 5.2 11.1 3.9 4.8 3.0 1.2 1.7 4.3 6.3 2.3 4.1 3.1 6.1 2.1 4.2 2.1 3.1 6.7 9.2 0.6 1.6 5.6 5.2 5.0 10.5 7.2 3.3 3.1 4.7 3.3 0.7 1.6 1.6 2.1 2.6 10.1 1.1 8.2 2.6 1.7 6.0 3.1 5.1 4.7 3.1 3.1 7.7 2.8 1.8 3.9 2.3 6.9 2.8 1.0 3.2 0.8 3.2 0.5 1.8 0.0 2.4 1.6 3.9 3.7 3.6 3.6 2.0 2.2 4.6 4.5 0.7 0.8 3.9 6.8 4.0 2.1 8.5 10.4 11.8 14.6 9.4 11.0 6.5 11.7 11.6 3.9 UEVLD "Attp, UEV3" ENSG00000151116 "UEV and lactate/malate dehyrogenase domains" Q8IX04 11 18529609-18588747 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047134 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA047134: AB_10960698" "unprognostic (1.05e-1)" "unprognostic (6.76e-2)" "prognostic favourable (7.07e-4)" "unprognostic (5.94e-3)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.38e-3)" "unprognostic (9.08e-3)" "unprognostic (9.81e-2)" "unprognostic (2.87e-2)" "unprognostic (1.26e-3)" "unprognostic (1.71e-2)" "unprognostic (1.61e-3)" "unprognostic (2.65e-1)" "unprognostic (3.22e-1)" "unprognostic (8.23e-2)" "unprognostic (3.39e-1)" 17.3 15.0 13.3 11.6 12.9 5.5 20.8 9.7 13.3 17.1 18.2 16.4 12.9 15.1 15.0 16.3 17.8 12.6 13.0 13.2 13.1 12.1 21.8 17.2 13.3 12.3 15.6 10.9 13.8 11.8 19.1 14.2 16.2 15.5 17.9 20.0 11.4 14.8 13.9 20.4 20.2 15.9 18.3 23.0 12.5 13.4 10.0 15.0 14.3 15.2 11.8 11.5 16.5 13.5 5.2 7.1 11.1 8.5 8.7 7.6 3.8 9.1 11.0 5.2 5.0 17.1 15.3 5.1 10.0 14.1 13.3 12.8 4.6 2.6 2.8 5.6 11.7 14.2 4.7 10.2 15.2 8.3 6.2 4.0 5.2 5.0 7.6 6.3 6.2 10.5 11.0 6.4 9.2 12.3 3.0 2.8 16.9 6.9 0.2 2.1 1.4 11.4 1.0 12.2 3.5 16.0 14.5 2.2 4.7 11.0 14.1 8.7 11.2 3.8 9.2 12.3 6.5 20.3 9.8 0.6 6.2 0.6 10.6 5.0 12.5 6.9 8.3 5.0 7.6 8.5 7.1 4.5 5.5 6.1 5.5 5.2 3.6 4.7 11.1 8.7 6.6 7.1 3.8 3.8 13.3 12.9 9.7 13.3 13.1 12.1 15.6 10.9 15.5 15.0 ZADH2 MGC45594 ENSG00000180011 "Zinc binding alcohol dehydrogenase domain containing 2" Q8N4Q0 18 75195108-75209348 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021468, HPA053646" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" Nucleoplasm "Golgi apparatus, Vesicles" "HPA021468: AB_1858932, HPA053646: " "unprognostic (3.22e-2)" "unprognostic (1.03e-2)" "unprognostic (7.14e-2)" "unprognostic (1.13e-1)" "unprognostic (4.79e-1)" "unprognostic (5.11e-3)" "unprognostic (1.15e-1)" "unprognostic (1.49e-1)" "unprognostic (3.62e-3)" "unprognostic (1.42e-1)" "unprognostic (3.05e-2)" "unprognostic (1.48e-1)" "prognostic favourable (1.02e-6)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "prognostic unfavourable (1.94e-4)" "unprognostic (2.23e-1)" 14.1 12.1 15.6 12.5 22.5 12.7 28.1 19.1 24.1 15.5 18.9 10.8 13.6 13.7 12.8 19.0 18.1 13.5 15.7 24.4 17.4 11.3 18.0 23.4 13.3 12.7 12.9 18.4 19.6 19.5 22.4 20.5 26.2 19.3 13.8 21.4 13.5 16.3 14.1 34.5 15.8 24.0 16.9 12.1 15.0 15.5 7.1 11.2 11.2 20.7 15.5 14.5 17.4 15.5 2.7 3.3 12.1 5.2 2.5 4.8 2.3 9.3 6.2 6.6 13.5 10.3 13.4 7.3 16.9 19.7 6.7 8.4 3.8 13.3 6.5 2.7 16.7 12.7 8.2 14.3 4.7 40.6 12.0 14.7 13.7 7.3 7.4 24.7 15.0 14.8 14.3 5.3 12.3 13.7 7.9 24.1 12.7 10.9 6.2 12.2 1.7 14.2 13.3 10.6 21.5 13.0 15.8 12.3 10.1 9.4 9.7 10.7 9.7 12.3 12.1 13.1 10.1 4.1 5.3 3.9 17.1 4.5 8.7 21.5 10.6 1.9 5.0 12.1 4.8 4.2 3.8 2.7 4.1 4.5 3.3 2.5 2.3 3.5 2.7 2.5 5.2 2.5 4.4 2.3 15.6 22.5 19.1 24.1 17.4 11.3 12.9 18.4 19.3 11.2