Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" BRSK1 KIAA1811 ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312533 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.0" "Cell line enhanced" "Detected in many" "SCLC-21H: 25.9;SH-SY5Y: 23.2;WM-115: 21.1" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported Nucleoplasm Nucleoplasm "HPA021212: AB_1845455, HPA061719: " "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favourable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavourable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" 1.4 9.8 28.6 3.2 23.6 1.0 1.6 26.7 65.0 1.8 2.2 7.9 0.1 3.3 5.4 3.7 3.0 2.3 3.9 6.5 33.4 20.0 1.4 0.8 1.7 2.4 20.4 14.8 2.4 2.6 12.4 11.0 1.5 13.3 3.8 1.9 2.8 2.5 4.6 1.0 1.1 2.6 4.9 9.2 1.5 1.9 4.4 7.2 0.0 3.0 0.0 1.6 3.2 0.7 0.0 0.3 0.0 0.9 0.1 0.8 0.2 0.3 1.2 15.3 8.0 0.0 0.6 0.1 2.4 3.4 3.3 4.8 5.9 2.7 3.1 1.7 2.7 0.1 3.2 0.1 3.1 14.4 12.6 2.0 1.6 0.6 3.3 0.6 5.9 2.1 0.3 3.3 0.0 0.1 2.8 18.8 2.9 0.8 3.6 0.7 11.1 1.0 8.3 3.8 0.5 0.2 0.0 25.9 23.2 0.0 0.4 5.6 1.3 1.7 0.0 6.3 6.7 3.5 4.6 15.6 11.4 7.0 6.5 1.4 21.1 0.0 0.9 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.2 28.6 23.6 26.7 40.2 33.4 20.0 20.4 14.8 13.3 7.2 BRSK2 "C11orf7, PEN11B, STK29" ENSG00000174672 "BR serine/threonine kinase 2" Q8IWQ3 11 1389899-1462689 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Exocytosis, Mitosis, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 34.9;pancreas: 78.8" "Cell line enhanced" "Detected in some" "AF22: 8.9;AN3-CA: 9.7;CACO-2: 7.7;HAP1: 7.2;NTERA-2: 15.0;SCLC-21H: 35.0" "Cancer enhanced" "Detected in many" "glioma: 3.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 13 "NK-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073690 Approved "Golgi apparatus" "Golgi apparatus" "HPA073690: " "unprognostic (5.47e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.05e-2)" "unprognostic (3.63e-1)" "unprognostic (6.42e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-2)" "unprognostic (2.31e-1)" "unprognostic (3.17e-7)" "unprognostic (3.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "unprognostic (1.86e-1)" 1.5 3.5 13.6 1.5 12.8 1.3 1.3 30.8 34.9 1.3 1.5 10.0 0.0 1.7 1.4 1.3 1.3 1.4 1.9 1.5 15.6 10.6 1.4 1.3 1.4 1.3 8.3 17.2 1.4 78.8 1.6 4.6 1.8 9.5 1.6 1.4 2.2 1.6 1.4 1.5 1.5 1.9 1.4 6.5 1.3 1.9 5.5 9.2 0.0 1.9 0.0 1.3 1.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 3.9 8.9 9.7 0.1 0.3 0.0 0.1 0.1 0.7 0.3 7.7 0.5 0.0 1.3 0.1 0.0 7.2 0.0 0.6 0.9 3.8 0.0 0.0 0.1 0.4 0.0 0.3 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.9 0.0 0.0 15.0 1.2 0.0 0.0 0.0 0.1 0.1 35.0 5.2 1.7 0.1 2.4 0.2 0.4 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 13.6 12.8 30.8 23.3 15.6 10.6 8.3 17.2 9.5 9.2 CAMK1 CaMKI ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757342-9769992 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.5;blood: 59.4" "Cell line enriched" "Detected in many" 4 "HMC-1: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "eosinophil: 59.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 59.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol 550000 Cytosol "CAB031904: AB_630964, HPA051409: " "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavourable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" 27.1 60.5 28.0 11.7 26.0 3.5 34.1 12.4 31.2 9.5 10.7 4.4 5.8 6.8 12.6 10.5 7.1 12.6 8.9 10.2 21.4 14.0 13.1 20.7 9.2 10.4 10.3 19.9 21.5 4.5 7.4 7.9 5.1 10.1 18.6 8.1 6.8 5.1 15.1 4.7 3.3 8.3 18.4 7.2 7.1 8.1 13.4 5.6 0.6 7.0 3.7 10.4 9.5 10.3 0.0 3.2 59.4 9.2 0.7 0.4 0.9 0.1 3.6 2.9 0.0 15.1 5.6 7.3 8.6 4.8 9.9 9.4 5.3 0.6 0.2 2.0 5.8 0.6 0.0 1.1 6.2 0.1 21.1 11.6 6.9 7.4 8.4 1.0 92.0 5.9 0.9 13.9 1.5 8.3 1.5 0.2 3.7 2.2 0.0 8.5 2.0 5.7 0.0 0.1 0.2 5.9 0.6 0.9 3.7 1.5 0.1 0.8 0.9 14.9 4.3 4.5 5.6 6.4 10.8 0.0 0.0 0.2 9.6 3.3 0.6 3.3 4.8 59.4 0.0 9.2 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.2 0.7 9.2 0.1 0.4 0.9 28.0 26.0 12.4 31.2 21.4 14.0 10.3 19.9 10.1 5.6 CAMK1D CKLiK ENSG00000183049 "Calcium/calmodulin dependent protein kinase ID" Q8IU85 10 12349482-12835545 "Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 46.7;U-266/70: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 31.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007266 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA007266: AB_1078389" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-3)" "unprognostic (4.23e-1)" "unprognostic (2.32e-2)" "unprognostic (6.90e-3)" "prognostic favourable (1.67e-4)" "unprognostic (1.06e-1)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (7.40e-2)" "unprognostic (1.35e-2)" "unprognostic (6.55e-2)" "unprognostic (1.65e-1)" "unprognostic (4.66e-2)" "unprognostic (2.56e-3)" 5.1 5.3 20.9 10.5 22.1 6.6 4.0 23.4 33.5 8.3 11.5 4.6 10.0 3.8 3.3 3.3 8.7 4.3 6.8 13.8 18.6 7.2 2.2 11.5 7.6 9.3 5.8 17.8 2.6 17.0 1.3 2.5 3.2 5.0 4.9 12.9 11.9 4.5 15.4 1.7 18.5 5.5 5.6 4.9 10.5 3.4 6.2 6.8 20.8 13.6 2.9 12.5 8.1 7.0 7.1 4.2 31.8 3.7 1.4 2.3 1.3 0.1 2.5 2.9 0.1 1.8 0.6 0.2 0.4 0.9 0.6 0.9 3.5 2.0 1.4 0.3 0.2 1.3 3.5 0.5 0.5 46.7 1.8 5.6 8.3 0.2 0.5 0.1 5.1 0.1 2.3 1.2 0.1 0.3 0.1 0.2 0.7 2.9 10.9 2.2 1.9 1.1 8.3 1.6 2.6 0.1 2.7 4.5 2.0 5.5 2.0 0.0 1.5 1.3 0.1 2.4 3.6 7.7 1.6 21.5 6.7 4.7 3.6 3.6 0.0 8.3 2.2 31.8 1.8 3.1 1.9 5.6 1.6 2.3 4.2 7.1 1.9 1.3 13.9 1.4 3.7 1.4 0.5 1.3 20.9 22.1 23.4 33.5 18.6 7.2 5.8 17.8 5.0 6.8 CAMK2A "CAMKA, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290291 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "brain: 105.7;skeletal muscle: 50.1" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;SCLC-21H: 9.5;U-87 MG: 8.0" "Cancer enriched" "Detected in single" 13 "glioma: 6.0" "Group enriched" "Detected in all" 6 "amygdala: 60.7;basal ganglia: 50.6;cerebral cortex: 99.6;hippocampal formation: 74.6;olfactory region: 39.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "amygdala: 1311.6;basal ganglia: 698.1;cerebral cortex: 1576.4;hippocampal formation: 1569.1" "Low region specificity" "Detected in all" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Approved "Plasma membrane,Cell Junctions,Cytosol" 21000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB004330: AB_626788, HPA051783: , HPA051785: , HPA053973: " "unprognostic (7.20e-3)" "unprognostic (6.47e-3)" "unprognostic (6.16e-3)" "unprognostic (4.85e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-3)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (3.07e-1)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-8)" "unprognostic (2.71e-4)" "unprognostic (1.68e-1)" "unprognostic (1.70e-2)" "unprognostic (1.36e-3)" 1.3 1.7 60.7 1.3 50.6 1.3 1.1 1.4 105.7 1.8 1.3 3.7 0.0 1.2 2.1 1.4 1.9 1.7 1.3 3.7 74.6 10.5 1.6 1.2 1.5 1.2 5.1 39.8 1.3 1.1 1.1 0.4 1.3 2.4 1.6 1.3 0.0 1.2 1.4 50.1 1.6 1.3 2.5 1.7 1.2 1.3 1.2 2.3 0.0 1.2 0.0 1.1 1.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.6 0.0 0.5 1.3 0.8 0.7 0.0 0.1 0.0 0.2 0.6 2.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.2 0.5 0.2 1.7 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.0 0.0 9.5 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.1 0.0 8.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 60.7 50.6 1.4 99.6 74.6 10.5 5.1 39.8 2.4 2.3 CAMK2B "CAM2, CAMK2, CAMKB" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;heart muscle: 39.2;skeletal muscle: 70.7" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 41.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" 680000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: , HPA051785: , HPA053973: " "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 1.4 8.1 20.6 1.4 46.7 1.2 2.0 60.1 81.9 1.2 1.4 4.0 0.7 1.7 1.3 18.8 2.0 1.8 1.2 39.2 36.5 18.0 1.7 3.5 1.2 1.8 10.3 21.3 1.1 3.3 5.6 9.9 1.1 13.4 3.0 1.4 2.7 1.8 2.2 70.7 1.8 1.6 1.2 4.1 1.3 2.4 2.3 4.8 0.0 7.7 2.4 2.0 1.1 0.0 1.3 1.0 3.2 1.2 3.2 1.2 0.8 0.0 0.3 0.2 0.3 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.8 0.2 0.1 0.2 0.7 0.0 1.0 2.4 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 5.2 0.0 0.2 0.1 2.3 0.1 0.9 0.1 0.0 0.0 41.0 2.2 0.2 0.0 0.0 1.9 0.1 0.2 0.2 0.3 0.2 0.0 0.5 0.4 0.1 0.1 0.0 0.2 3.2 0.7 1.0 0.8 0.9 1.2 1.1 1.0 0.5 0.5 1.3 1.2 1.1 2.0 3.2 1.2 1.0 0.9 0.8 20.6 46.7 60.1 42.4 36.5 18.0 10.3 21.3 13.4 4.8 CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113451032-113761927 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" 140000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: , HPA051785: , HPA053973: " "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" 22.8 12.9 47.7 18.3 13.0 2.8 23.5 50.2 30.6 11.0 18.2 7.4 28.6 13.6 11.6 9.4 15.6 9.6 14.8 77.1 17.9 21.4 9.6 17.6 14.7 17.5 14.0 23.8 12.9 7.4 33.7 7.0 9.3 12.5 16.3 19.0 9.9 9.4 48.3 48.5 10.8 19.2 26.2 16.0 8.4 17.6 9.4 8.5 11.2 11.6 9.8 14.5 21.5 22.6 18.5 11.2 0.6 8.8 6.4 9.7 5.2 1.0 14.3 15.8 5.3 34.6 66.2 5.6 33.5 22.4 13.2 11.4 9.6 4.0 20.5 4.9 23.3 0.5 9.8 5.2 13.5 7.8 2.5 0.0 5.2 11.0 17.5 0.0 0.0 42.3 7.2 10.2 25.3 11.7 0.8 9.2 24.8 3.8 2.0 0.8 2.2 5.3 4.0 18.5 0.1 13.5 9.7 4.3 4.3 4.5 6.8 4.5 0.1 5.5 7.0 34.9 8.2 14.8 6.6 7.1 3.6 17.6 18.0 1.2 16.4 0.0 8.8 0.0 5.1 5.1 9.7 8.0 5.0 5.6 11.2 18.5 5.8 4.9 0.6 6.4 1.7 0.0 9.3 5.2 47.7 13.0 50.2 25.6 17.9 21.4 14.0 23.8 12.5 8.5 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.0" "Cell line enhanced" "Detected in all" "PC-3: 45.4;SK-BR-3: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" 170000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: , HPA051783: , HPA051785: , HPA053973: " "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 9.1 8.8 27.4 9.4 20.7 17.4 6.8 22.2 53.8 9.0 37.3 13.3 9.7 19.7 20.1 9.1 20.6 13.2 10.6 6.7 22.8 24.4 11.6 5.9 10.7 8.9 26.8 31.2 6.4 5.7 8.0 6.0 15.8 38.6 18.5 15.5 8.5 12.4 29.8 73.0 9.1 18.1 29.6 29.8 11.0 14.2 3.8 13.4 4.4 6.4 7.6 8.7 26.5 10.8 4.2 7.1 39.8 5.6 9.8 9.2 5.0 10.9 7.9 7.1 13.6 5.2 8.6 8.4 7.5 12.9 10.4 8.5 12.2 11.8 8.1 7.9 9.7 17.0 5.6 6.4 8.3 7.3 6.7 5.5 6.1 5.5 2.6 7.5 9.3 4.5 5.8 10.3 7.2 8.8 6.0 12.1 5.7 7.6 12.5 11.2 5.2 45.4 11.4 7.5 4.3 5.4 15.9 3.7 8.6 4.3 57.2 3.7 10.7 4.7 10.8 7.7 12.4 4.2 10.1 3.7 4.4 7.5 8.3 21.5 2.7 8.5 5.6 39.8 7.5 2.3 9.2 4.2 8.4 8.0 7.1 3.9 8.1 7.9 36.4 9.8 4.0 2.4 8.1 5.0 27.4 20.7 22.2 53.8 22.8 24.4 26.8 31.2 38.6 13.4 CAMK4 CaMK-GR ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.9;lymphoid tissue: 71.7" "Cell line enhanced" "Detected in many" "HDLM-2: 41.2;MOLT-4: 12.6;SH-SY5Y: 16.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 14.1;memory CD4 T-cell: 10.3;memory CD8 T-cell: 7.8;naive CD4 T-cell: 19.8;naive CD8 T-cell: 10.9;T-reg: 11.3" "Lineage enriched" "Detected in single" 26 "T-cells: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 1.1 6.5 9.5 6.4 34.2 4.6 1.0 48.9 16.5 1.8 2.3 1.0 0.0 2.4 1.3 0.8 1.4 0.9 2.7 0.9 5.9 3.2 1.4 2.5 1.9 12.0 2.3 6.8 1.4 0.9 0.3 1.3 0.6 3.4 5.8 2.5 0.1 1.7 2.6 0.8 0.9 3.8 1.5 2.0 4.2 2.6 13.8 6.6 71.7 1.0 0.0 8.1 2.8 1.1 0.7 0.0 0.4 0.0 0.6 19.8 3.4 0.0 0.0 1.4 1.0 0.3 1.1 0.0 0.3 3.2 3.8 3.7 0.0 0.0 0.0 2.0 0.1 0.1 3.1 0.3 2.8 41.2 2.6 0.6 1.3 0.0 0.1 0.2 0.1 0.1 0.0 8.0 0.8 0.6 0.0 1.5 0.2 0.0 12.6 0.0 1.9 0.1 1.9 2.4 0.1 1.4 0.0 9.1 16.1 0.5 0.0 2.7 0.0 0.2 0.0 7.8 4.6 0.0 6.9 1.3 0.1 0.0 3.8 0.0 3.0 0.0 0.0 0.0 2.8 0.0 14.1 0.7 10.3 7.8 0.0 0.2 19.8 10.9 0.4 0.6 0.0 0.0 11.3 3.4 9.5 34.2 48.9 15.1 5.9 3.2 2.3 6.8 3.4 6.6 CAMKV "MGC8407, VACAMKL" ENSG00000164076 "CaM kinase like vesicle associated" Q8NCB2 3 49857988-49870222 "Enzymes, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "brain: 77.2" "Cell line enhanced" "Detected in some" "AF22: 5.2;HAP1: 6.9;NTERA-2: 24.6;RPMI-8226: 4.7;SCLC-21H: 8.4;SH-SY5Y: 5.4" "Group enriched" "Detected in some" 11 "glioma: 4.0;testis cancer: 5.2" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 12 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007656, CAB034931" Enhanced Supported Approved "Nucleoplasm,Cytokinetic bridge" Nucleoplasm "Cytokinetic bridge" "CAB034931: AB_2068550, HPA007656: AB_1078391" "unprognostic (9.47e-4)" "unprognostic (5.65e-3)" "unprognostic (1.42e-1)" "unprognostic (2.70e-7)" "unprognostic (2.76e-1)" "unprognostic (7.95e-4)" "unprognostic (3.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.48e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (8.11e-2)" "unprognostic (1.00e-3)" "unprognostic (7.61e-2)" "unprognostic (9.51e-2)" "unprognostic (1.67e-3)" 1.2 2.1 20.7 1.2 77.2 1.2 1.2 0.5 62.8 1.2 1.2 1.7 0.0 1.2 1.2 1.2 1.2 1.2 1.2 1.2 33.4 11.7 1.2 1.2 1.2 1.2 3.3 23.5 1.2 1.2 1.2 1.8 1.2 2.1 1.2 1.2 0.0 1.2 1.2 1.2 1.3 1.2 1.2 1.9 1.2 1.3 2.1 6.0 0.0 1.2 0.0 1.2 1.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.7 0.1 24.6 0.1 0.7 0.0 4.7 0.0 0.0 8.4 5.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 20.7 77.2 0.5 34.0 33.4 11.7 3.3 23.5 2.1 6.0 CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923645 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 26.3" "Lineage enriched" "Detected in many" 11 "granulocytes: 26.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB001949: , HPA023857: AB_1846035" "unprognostic (6.30e-2)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-3)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (5.85e-3)" "prognostic unfavourable (6.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "unprognostic (2.85e-2)" 9.1 15.9 13.9 18.8 12.7 9.8 13.2 14.2 15.7 11.1 22.1 20.0 7.1 27.1 12.2 13.7 17.2 9.9 16.0 7.0 12.1 12.8 14.6 10.8 10.3 13.6 16.3 8.5 13.9 14.2 11.1 9.8 13.4 11.9 10.7 23.8 10.4 15.9 7.7 5.8 12.8 32.9 12.1 10.1 9.6 16.2 2.9 14.3 30.9 9.3 8.1 14.0 11.8 13.1 0.6 0.3 26.3 0.8 2.4 2.3 0.3 10.8 13.9 13.3 7.9 9.0 7.4 4.3 9.5 7.9 5.6 5.1 29.9 17.7 0.1 4.9 11.8 21.8 14.7 9.7 9.4 9.6 8.2 0.0 12.5 10.6 9.3 1.7 1.4 8.4 26.7 10.6 13.6 4.5 0.8 8.5 12.1 12.7 3.1 0.7 12.2 9.1 5.1 32.8 5.2 12.6 23.7 12.2 6.5 17.9 7.1 5.4 7.7 0.3 5.3 10.5 10.6 8.9 5.2 3.3 2.0 3.6 10.3 1.2 6.7 26.3 0.8 4.8 0.5 0.7 0.5 0.4 0.6 0.8 0.2 0.6 0.7 0.7 1.1 2.4 0.4 0.3 2.3 0.3 13.9 12.7 14.2 14.2 12.1 12.8 16.3 8.5 11.9 14.3 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625136-125676255 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ductus deferens: 80.0;seminal vesicle: 66.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 11.7" "Lineage enriched" "Detected in many" 6 "T-cells: 11.7" "Low region specificity" "Detected in single" HPA044364 Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA044364: " "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favourable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavourable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavourable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavourable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 3.0 2.5 2.5 9.0 2.8 14.9 2.1 1.1 2.2 2.5 5.2 1.3 80.0 5.0 1.9 10.2 6.5 1.7 3.6 1.5 2.4 2.4 3.7 2.0 1.8 9.6 3.0 1.2 3.8 4.0 25.5 3.5 3.8 1.5 2.9 6.3 1.6 2.6 66.8 1.2 2.9 5.2 2.3 3.0 3.6 2.8 7.2 1.5 22.4 1.8 4.5 8.8 3.8 3.3 1.9 1.8 1.9 0.7 1.2 11.7 1.0 12.7 10.4 23.4 14.2 4.8 10.3 10.2 17.9 8.6 11.5 12.4 25.4 28.3 33.4 18.5 7.0 15.4 14.3 9.4 14.2 20.9 6.6 61.9 8.7 13.0 1.5 31.6 11.8 5.3 2.0 14.5 10.3 13.6 31.3 29.4 15.1 6.6 46.9 15.5 23.7 9.4 28.6 21.9 17.5 10.6 17.0 14.8 15.7 14.7 10.2 4.3 27.5 10.3 9.1 16.6 14.1 8.0 16.4 6.6 11.8 47.6 6.1 23.8 19.4 1.9 0.5 0.3 1.3 0.7 1.2 1.9 3.5 1.6 1.1 1.5 3.3 2.0 0.4 1.2 0.4 1.8 11.7 1.0 2.5 2.8 1.1 2.2 2.4 2.4 3.0 1.2 1.5 1.5 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavourable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 5.6 8.3 2.5 13.0 7.0 13.7 5.6 0.7 5.6 6.6 9.8 2.5 4.8 6.8 4.8 10.9 10.0 4.3 6.0 6.0 4.1 2.3 5.3 6.5 7.9 10.1 6.7 1.6 12.9 6.7 1.2 4.2 10.1 5.1 8.3 10.6 8.7 7.0 5.8 2.2 6.3 8.5 5.4 5.0 9.8 5.8 9.7 3.6 13.1 7.5 4.8 13.7 6.2 6.7 11.8 8.7 6.5 8.4 2.9 4.4 3.7 14.7 4.7 13.5 16.7 3.8 19.2 8.7 7.3 8.6 9.7 14.2 12.0 10.1 17.4 6.2 5.1 14.2 20.5 13.4 11.3 12.4 15.7 22.9 9.0 19.8 3.8 14.5 16.8 8.1 6.2 12.4 11.0 10.7 13.8 15.2 9.0 20.7 11.6 23.3 19.0 12.0 25.3 9.2 20.3 6.0 6.1 7.9 4.5 8.1 14.5 8.0 9.9 13.4 3.7 7.8 9.3 6.8 3.8 9.2 16.2 34.0 7.4 15.2 9.9 6.5 3.7 1.2 1.1 8.4 2.3 11.8 2.2 2.1 8.7 8.4 4.4 2.8 0.3 2.9 4.1 7.0 2.8 3.7 2.5 7.0 0.7 5.6 4.1 2.3 6.7 1.6 5.1 3.6 DAPK1 "DAPK, ROCO3" ENSG00000196730 "Death associated protein kinase 1" P53355 9 87497228-87708633 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Apoptosis, Translation regulation" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 94.7" "Cell line enhanced" "Detected in many" "HMC-1: 38.7;HUVEC TERT2: 21.9;RPTEC TERT1: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.3;eosinophil: 6.9;intermediate monocyte: 11.9;myeloid DC: 4.0;non-classical monocyte: 11.7;plasmacytoid DC: 5.3" "Group enriched" "Detected in many" 55 "dendritic cells: 5.3;granulocytes: 6.9;monocytes: 11.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB037302, HPA040472, HPA048436" Approved Approved Centrosome Centrosome "CAB037302: AB_1078622, HPA040472: , HPA048436: " "unprognostic (2.55e-1)" "unprognostic (1.47e-1)" "prognostic unfavourable (2.48e-5)" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.75e-1)" "unprognostic (1.88e-2)" "unprognostic (5.77e-3)" "unprognostic (2.19e-2)" "unprognostic (2.77e-3)" "unprognostic (8.31e-3)" "unprognostic (8.76e-2)" "unprognostic (2.40e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-3)" 14.6 4.9 10.4 8.8 25.5 3.8 4.1 2.9 17.6 8.1 16.6 6.5 8.1 7.8 8.7 16.1 4.5 12.2 21.6 4.1 12.4 8.1 14.7 21.3 28.6 8.5 4.6 10.4 32.7 21.2 4.8 16.6 94.7 6.6 5.1 7.5 5.9 9.3 7.3 1.5 3.7 11.0 8.1 4.8 16.4 15.0 6.3 7.3 34.5 7.2 1.5 5.2 13.2 10.5 0.1 5.3 6.9 11.9 0.1 0.1 2.1 0.0 18.2 8.8 6.1 0.2 0.1 14.0 1.2 1.7 7.2 8.1 2.6 0.1 0.1 1.8 0.3 17.0 5.4 0.4 3.1 0.1 4.4 8.8 2.5 8.9 7.8 0.0 38.7 0.5 2.9 1.3 0.5 21.9 6.6 3.7 6.0 0.5 2.6 0.0 9.9 0.0 0.7 7.8 0.0 20.0 18.2 4.0 4.5 0.0 1.8 7.7 0.0 5.8 0.1 0.0 0.1 0.0 0.0 14.6 3.0 0.0 0.1 2.4 1.2 1.3 5.3 6.9 0.0 11.9 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 1.6 0.1 11.7 5.3 0.0 2.1 10.4 25.5 2.9 17.6 12.4 8.1 4.6 10.4 6.6 7.3 DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 51.8;skeletal muscle: 46.1" "Cell line enhanced" "Detected in many" "ASC diff: 10.0;HaCaT: 8.3;HMC-1: 17.0;MCF7: 8.6" "Cancer enriched" "Detected in many" 15 "thyroid cancer: 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 19.1;eosinophil: 51.8;neutrophil: 16.4" "Lineage enriched" "Detected in many" 23 "granulocytes: 51.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA071581: " "unprognostic (3.20e-2)" "unprognostic (4.07e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-3)" "unprognostic (2.88e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "prognostic favourable (5.63e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (8.51e-2)" "unprognostic (4.77e-7)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-3)" "unprognostic (9.07e-2)" 8.2 1.6 2.6 6.8 5.0 10.3 5.2 1.4 3.9 3.6 16.6 12.0 8.3 14.2 1.7 1.5 2.1 1.2 1.7 17.6 3.6 2.0 2.2 1.4 14.0 2.5 6.8 3.0 0.7 1.7 1.1 1.1 0.3 4.7 3.1 4.7 1.9 4.8 4.8 46.1 4.6 25.8 1.2 3.4 4.7 6.9 2.0 6.5 1.1 22.3 8.7 3.3 2.1 9.6 0.3 2.2 51.8 0.0 0.7 0.6 0.3 2.8 2.0 5.6 1.4 10.0 0.4 0.1 1.9 6.0 1.0 1.1 0.8 1.4 0.2 0.6 6.0 8.3 3.5 0.1 0.6 0.2 0.1 1.1 3.9 0.1 0.1 0.1 17.0 1.0 7.2 0.3 0.2 0.6 0.4 0.1 0.7 8.6 0.0 0.3 0.6 2.0 2.6 0.0 0.3 0.0 2.8 0.4 0.3 0.4 1.1 0.0 4.8 0.4 0.4 0.8 1.0 1.3 1.6 0.6 0.2 0.0 0.0 2.7 0.2 19.1 0.0 51.8 0.6 0.0 0.2 0.3 0.1 0.5 0.0 0.1 0.0 0.4 16.4 0.7 0.0 2.2 0.0 0.3 2.6 5.0 1.4 3.9 3.6 2.0 6.8 3.0 4.7 6.5 DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028569, HPA064809" Approved Approved Nucleoplasm Nucleoplasm "HPA028569: AB_10794319, HPA064809: " "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.34e-3)" "prognostic favourable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (2.37e-1)" "unprognostic (7.72e-3)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-3)" "unprognostic (7.64e-2)" "prognostic unfavourable (6.49e-4)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" 18.8 10.2 12.6 16.6 16.4 10.0 17.2 14.5 29.5 22.5 30.1 13.6 11.5 18.5 33.1 11.5 20.2 18.5 21.9 49.2 12.4 11.0 10.9 11.0 24.5 11.6 11.9 16.8 18.8 21.7 11.1 14.6 26.0 19.7 21.3 6.9 18.2 15.3 25.8 45.2 17.8 17.0 38.8 10.6 14.7 23.3 15.7 12.7 11.8 11.4 11.6 12.9 26.7 17.8 15.0 14.7 23.9 15.6 17.3 19.5 11.0 25.5 20.3 12.7 16.0 9.5 10.8 19.6 35.3 28.5 28.9 19.1 37.4 7.7 14.2 17.3 30.9 20.4 12.4 20.0 10.5 20.7 20.6 5.7 24.9 21.4 30.3 13.7 21.5 24.5 25.0 26.1 15.1 23.9 18.0 24.7 17.5 16.6 13.5 10.3 19.7 16.3 17.0 18.8 13.2 17.4 20.1 20.1 14.0 23.7 28.7 20.2 20.6 10.8 44.6 37.1 16.8 33.2 44.0 27.6 22.6 16.4 29.6 14.4 19.8 22.1 14.2 23.9 19.5 15.6 14.0 13.5 14.8 17.9 12.6 15.0 11.3 10.8 23.9 17.3 10.6 14.7 17.6 11.0 12.6 16.4 14.5 29.5 12.4 11.0 11.9 16.8 19.7 12.7 DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131306 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 76.5" "Cell line enhanced" "Detected in some" "ASC diff: 17.3;ASC TERT1: 16.4;fHDF/TERT166: 13.3;HAP1: 10.3;HSkMC: 15.1;NTERA-2: 21.4" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol 11000 Nucleoplasm Cytosol "CAB012405: , HPA015040: , HPA015655: " "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.72e-2)" "unprognostic (2.85e-1)" "prognostic unfavourable (4.42e-4)" "unprognostic (1.93e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-4)" 13.9 3.3 14.3 4.2 25.0 1.1 8.6 8.6 76.5 12.2 3.5 8.6 0.5 2.0 6.4 5.8 5.8 3.3 7.1 5.8 21.9 21.9 1.9 1.2 3.0 4.3 11.9 22.5 6.4 2.1 1.5 7.4 1.1 13.9 4.7 4.4 0.5 2.5 4.7 1.9 4.7 2.7 17.0 10.4 4.6 2.5 2.2 8.5 0.0 2.1 1.4 2.9 5.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.0 17.3 16.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 13.3 0.0 10.3 0.2 0.0 0.0 0.6 0.0 0.4 0.0 0.6 0.0 0.0 15.1 7.5 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 21.4 0.2 0.0 1.2 0.0 0.6 0.0 4.3 2.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.5 4.4 0.7 0.1 0.0 0.0 1.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 25.0 8.6 45.8 21.9 21.9 11.9 22.5 13.9 8.5 DCLK2 "DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428" ENSG00000170390 "Doublecortin like kinase 2" Q8N568 4 150078274-150257457 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 60.5" "Cell line enhanced" "Detected in many" "AF22: 18.2;BJ hTERT+: 19.0;fHDF/TERT166: 8.3" "Cancer enriched" "Detected in many" 17 "glioma: 53.3" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 2.5;plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015770 Enhanced "HPA015770: AB_1847509" "unprognostic (7.37e-2)" "unprognostic (1.56e-3)" "unprognostic (9.30e-2)" "unprognostic (1.49e-2)" "unprognostic (4.06e-1)" "unprognostic (6.24e-3)" "unprognostic (1.90e-1)" "unprognostic (7.38e-3)" "unprognostic (2.18e-1)" "prognostic favourable (3.25e-4)" "prognostic favourable (2.48e-4)" "unprognostic (6.87e-2)" "unprognostic (3.93e-3)" "unprognostic (3.74e-3)" "unprognostic (4.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.45e-2)" 2.9 3.9 23.3 2.1 23.5 1.6 2.0 9.3 60.5 3.1 2.8 16.5 0.8 2.8 4.3 3.5 3.0 2.8 4.0 14.4 23.5 17.5 2.9 1.8 2.7 1.6 14.9 14.5 4.3 3.5 1.4 4.7 2.9 20.2 3.9 3.5 2.1 2.0 3.6 2.3 2.1 2.7 6.4 23.4 2.1 2.2 4.2 15.9 0.0 4.1 0.0 1.5 3.3 2.0 2.5 1.5 0.0 0.5 0.0 0.0 0.0 0.8 3.2 18.2 2.8 0.0 0.9 0.3 8.2 19.0 2.7 0.6 0.1 0.0 0.0 0.3 8.3 0.0 2.6 0.0 3.4 3.7 1.6 0.0 4.7 0.0 3.9 0.5 0.5 0.5 0.0 1.6 0.2 0.9 0.0 0.0 1.9 0.1 0.3 0.0 0.3 1.0 0.0 2.1 0.7 0.0 0.8 7.0 6.6 3.4 2.5 0.8 0.0 0.0 1.6 2.5 1.0 1.6 0.9 0.8 0.0 0.0 2.4 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 23.3 23.5 9.3 19.3 23.5 17.5 14.9 14.5 20.2 15.9 DCLK3 "DCAMKL3, DCDC3C, KIAA1765" ENSG00000163673 "Doublecortin like kinase 3" Q9C098 3 36712422-36764349 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 10.0;testis: 8.0" "Cell line enhanced" "Detected in some" "NTERA-2: 3.3;SCLC-21H: 3.2;SH-SY5Y: 2.6;U-2 OS: 1.8;U-2197: 2.5" "Cancer enhanced" "Detected in single" "testis cancer: 1.2" "Region enhanced" "Detected in many" "basal ganglia: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040685 Approved "HPA040685: " "unprognostic (9.09e-3)" "unprognostic (1.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.66e-2)" "unprognostic (2.41e-1)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.96e-2)" "unprognostic (1.86e-2)" "unprognostic (2.05e-1)" "unprognostic (7.07e-2)" "unprognostic (6.11e-5)" "unprognostic (7.94e-3)" "unprognostic (5.80e-2)" "unprognostic (3.25e-3)" "unprognostic (1.36e-2)" 1.1 0.4 2.6 1.4 10.0 0.3 0.1 0.1 2.3 0.5 0.2 0.3 0.0 0.5 0.3 0.1 0.1 0.2 0.6 0.9 1.4 0.9 0.0 0.1 0.3 0.2 0.6 0.0 0.0 0.2 0.4 1.8 1.1 0.4 0.3 0.3 1.3 1.7 0.2 2.7 0.4 0.4 0.9 0.7 0.1 0.0 8.0 3.2 0.0 0.9 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.2 3.2 2.6 0.1 0.3 0.0 0.0 0.4 0.3 0.0 1.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 10.0 0.1 2.3 1.4 0.9 0.6 0.0 0.4 3.2 HUNK ENSG00000142149 "Hormonally up-regulated Neu-associated kinase" P57058 21 31873315-32044633 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 10.4;BEWO: 12.9;RH-30: 14.2;SCLC-21H: 11.6;SiHa: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027295, HPA027372" Approved Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA027295: , HPA027372: " "unprognostic (9.09e-3)" "unprognostic (7.29e-2)" "unprognostic (1.42e-1)" "unprognostic (5.95e-3)" "unprognostic (1.99e-1)" "unprognostic (2.12e-4)" "unprognostic (4.00e-2)" "unprognostic (6.90e-2)" "unprognostic (5.07e-1)" "unprognostic (2.27e-1)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "prognostic favourable (7.48e-5)" "unprognostic (8.84e-2)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.69e-2)" 1.7 1.9 2.7 2.9 3.5 0.5 2.1 3.2 6.4 1.1 5.9 0.2 12.6 2.4 9.0 3.4 1.1 3.3 1.0 1.7 3.7 3.2 6.0 1.3 1.7 0.7 1.2 2.1 1.8 15.7 0.2 4.7 7.6 1.4 4.0 6.5 9.1 1.5 11.1 0.6 5.0 4.4 4.1 0.9 0.4 2.1 1.8 0.2 0.4 1.1 2.2 1.0 3.8 7.7 1.0 0.7 1.7 0.5 0.5 0.5 0.1 0.0 3.0 10.4 0.1 0.0 0.0 12.9 1.0 0.0 0.2 0.0 4.1 0.1 0.0 0.4 4.8 0.0 6.2 0.0 0.0 0.0 3.1 0.0 2.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.9 7.9 0.1 0.1 14.2 0.0 1.1 0.0 11.6 7.7 10.2 0.8 0.4 4.2 1.1 0.0 0.0 7.4 0.0 0.0 0.1 0.0 1.4 0.0 0.0 4.9 0.8 0.5 0.5 0.5 0.3 0.3 0.5 0.5 0.3 0.2 1.0 0.5 0.5 1.7 0.5 0.3 0.7 0.4 0.1 2.7 3.5 3.2 6.4 3.7 3.2 1.2 2.1 1.4 0.2 KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124080023-124726325 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.2;retina: 31.2" "Cell line enhanced" "Detected in many" "CACO-2: 32.1;HEL: 19.6;SH-SY5Y: 9.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 4.3" "Lineage enriched" "Detected in single" 5 "T-cells: 4.3" "Low region specificity" "Detected in many" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol 110000 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" 5.5 4.3 12.7 2.4 14.1 0.6 4.2 1.8 35.2 4.0 3.8 3.7 0.5 2.7 5.6 2.3 9.6 4.2 3.1 12.1 17.6 3.9 2.6 7.3 2.9 1.1 4.1 15.8 2.3 11.9 2.5 14.4 6.8 9.4 3.1 2.1 31.2 2.2 5.4 23.5 1.5 7.2 6.4 3.6 8.0 11.5 2.2 2.4 0.0 5.3 6.7 3.1 2.9 4.1 0.1 0.0 0.9 0.0 0.1 4.3 1.2 0.3 0.6 3.6 0.7 0.5 0.1 4.6 1.4 0.8 1.4 0.6 32.1 2.5 0.1 0.4 3.6 0.2 0.8 0.0 1.1 0.0 0.3 19.6 0.3 4.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.6 4.5 0.1 0.4 2.3 0.0 0.0 2.0 3.1 1.0 1.6 0.0 0.1 0.3 1.2 9.2 0.4 0.3 0.3 0.7 0.1 8.1 4.1 1.6 0.6 0.6 0.0 0.3 0.0 0.5 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.3 0.0 0.0 2.4 0.7 0.9 0.1 0.0 0.0 4.3 1.2 12.7 14.1 1.8 35.2 17.6 3.9 4.1 15.8 9.4 2.4 MAPKAPK2 ENSG00000162889 "Mitogen-activated protein kinase-activated protein kinase 2" P49137 1 206684944-206734283 "Cancer-related genes, Enzymes, Predicted membrane proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in all" 6 "dendritic cells: 18.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010297, HPA045556, HPA063708, HPA064435" Approved Supported Nucleoplasm,Centrosome Nucleoplasm Centrosome "CAB010297: AB_2250405, HPA045556: , HPA063708: , HPA064435: " "unprognostic (7.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-2)" "prognostic unfavourable (1.93e-4)" "unprognostic (9.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "prognostic unfavourable (4.58e-6)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (6.96e-2)" "unprognostic (3.29e-2)" 23.0 25.3 11.6 21.2 15.7 58.6 23.9 11.1 14.5 19.3 25.6 17.2 14.5 25.7 20.0 18.5 23.5 17.3 26.0 89.2 12.3 8.7 33.7 26.7 26.7 21.5 16.7 6.5 23.3 19.1 16.9 22.8 13.6 15.7 20.2 14.4 17.8 19.8 14.4 62.9 18.3 32.9 18.3 14.6 37.7 23.1 21.3 14.6 26.9 24.3 25.2 28.2 22.9 46.1 1.1 18.7 3.2 1.1 2.3 1.6 0.5 20.9 8.3 11.5 12.9 34.0 20.0 14.3 14.6 33.1 22.3 21.1 15.8 10.2 10.1 10.2 29.4 15.9 8.6 15.5 16.1 11.7 6.5 16.9 10.3 10.2 26.3 24.9 56.6 27.5 19.9 21.4 23.7 18.2 19.4 45.9 18.0 26.0 10.0 18.0 13.3 11.6 25.8 24.1 3.2 16.8 12.8 9.2 11.9 17.2 29.1 20.2 14.1 24.2 17.3 20.1 17.0 23.3 19.8 59.8 53.1 8.2 22.8 15.2 6.6 1.1 0.7 1.4 1.6 1.1 1.5 1.0 1.2 1.5 0.6 1.1 0.6 1.1 3.2 2.3 1.0 18.7 1.4 0.5 11.6 15.7 11.1 14.5 12.3 8.7 16.7 6.5 15.7 14.6 MAPKAPK3 "3pK, MAPKAP3" ENSG00000114738 "Mitogen-activated protein kinase-activated protein kinase 3" Q16644 3 50611520-50649297 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 86.7;skeletal muscle: 70.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 30.2;eosinophil: 23.0;intermediate monocyte: 50.0;myeloid DC: 27.1;neutrophil: 20.5;non-classical monocyte: 61.4;plasmacytoid DC: 16.9" "Group enriched" "Detected in all" 5 "dendritic cells: 27.1;granulocytes: 23.0;monocytes: 61.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm Nucleoplasm "HPA058275: " "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favourable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favourable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" 8.9 16.1 5.6 9.3 7.2 30.4 6.3 1.9 6.2 5.5 9.5 7.1 7.5 9.9 5.5 8.6 16.8 5.1 8.5 86.7 4.8 3.7 17.9 11.9 11.0 15.1 7.2 4.1 8.7 24.2 11.2 9.0 9.0 6.0 7.6 6.7 10.9 12.4 9.2 70.1 17.6 12.0 5.2 5.9 12.5 9.0 4.0 5.2 25.9 22.6 40.9 14.3 6.1 7.5 3.0 27.1 23.0 61.4 7.3 6.4 19.5 23.0 7.1 3.0 8.5 4.6 11.5 6.7 5.6 8.0 8.7 7.4 11.1 21.5 9.3 5.7 18.7 8.2 20.5 22.1 7.8 20.4 4.9 48.7 10.2 10.1 9.1 35.0 25.9 9.1 13.8 20.2 27.5 7.6 13.6 6.1 18.2 9.4 14.9 35.3 11.2 29.5 6.6 7.2 13.9 40.3 13.2 5.6 4.0 5.0 14.2 6.4 8.9 21.7 5.5 6.8 15.7 35.3 13.8 4.1 7.6 7.7 36.4 55.1 2.8 6.4 30.2 23.0 5.5 50.0 5.4 3.0 6.2 6.4 27.1 1.8 4.9 5.5 20.5 7.3 61.4 16.9 5.2 19.5 5.6 7.2 1.9 6.2 4.8 3.7 7.2 4.1 6.0 5.2 MAPKAPK5 PRAK ENSG00000089022 "Mitogen-activated protein kinase-activated protein kinase 5" Q8IW41 12 111841978-111902238 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB004546: AB_627910, HPA015515: AB_1853569" "unprognostic (6.45e-2)" "unprognostic (7.29e-2)" "unprognostic (1.27e-3)" "unprognostic (1.09e-2)" "unprognostic (5.52e-2)" "unprognostic (3.76e-2)" "prognostic unfavourable (2.98e-8)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (3.20e-1)" "unprognostic (6.03e-2)" "unprognostic (3.39e-2)" "unprognostic (9.41e-2)" "unprognostic (3.25e-2)" 20.7 26.2 21.4 17.5 26.4 24.1 21.7 23.7 28.3 17.3 28.8 26.1 21.9 26.3 25.8 22.8 20.8 17.5 22.7 20.7 17.7 15.2 21.7 21.5 18.9 19.4 22.3 20.4 21.3 24.5 19.8 20.4 21.0 17.3 18.7 32.9 23.6 23.3 20.5 33.2 23.0 28.4 21.1 18.0 18.4 19.8 16.7 22.0 19.3 20.5 15.1 19.3 19.9 16.5 4.9 4.1 3.2 11.4 3.9 6.8 2.5 15.1 20.2 19.5 16.4 14.1 14.3 29.7 15.2 18.4 23.4 16.2 26.0 12.5 22.9 11.3 17.9 15.2 25.6 15.9 22.0 15.2 14.0 20.4 14.0 20.8 17.1 25.6 14.5 15.1 22.9 22.3 26.6 17.1 28.1 9.1 17.0 17.0 25.4 40.5 27.7 14.2 25.2 14.2 22.0 18.6 22.0 24.1 20.4 17.3 29.5 21.1 23.8 29.3 14.9 13.3 13.4 13.6 19.0 18.6 22.7 27.1 16.2 18.7 18.8 1.3 4.8 3.2 6.5 3.5 3.5 4.9 4.3 4.7 3.3 4.0 6.8 5.1 2.5 3.9 11.4 4.1 6.6 2.5 21.4 26.4 23.7 28.3 17.7 15.2 22.3 20.4 17.3 22.0 MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528183-220664461 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 9.4;RT4: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain "HPA007421: AB_1079311, HPA008061: AB_1079310" "unprognostic (1.51e-1)" "unprognostic (6.27e-2)" "unprognostic (6.72e-2)" "unprognostic (3.63e-2)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-2)" "unprognostic (3.48e-1)" "prognostic unfavourable (2.63e-4)" "unprognostic (4.59e-2)" "prognostic favourable (2.23e-5)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (9.56e-3)" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" 14.3 5.6 11.4 4.6 13.5 0.9 9.0 15.2 22.7 9.8 6.7 4.7 6.4 2.1 7.8 26.6 9.4 5.9 5.0 19.1 10.0 12.5 4.7 1.5 4.8 2.3 10.3 12.4 3.7 3.0 5.8 12.1 3.9 13.2 7.2 4.1 6.2 5.0 11.3 4.2 3.5 3.4 10.1 7.1 3.2 4.3 16.0 4.6 0.4 8.4 5.3 5.7 8.8 14.9 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 4.5 1.2 0.0 0.0 1.8 1.5 2.2 1.5 2.3 0.0 0.0 0.0 0.0 0.0 2.3 9.4 6.1 1.1 0.0 6.9 0.0 2.4 0.0 0.0 0.7 0.9 0.7 5.2 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.7 2.2 0.0 7.0 0.0 0.0 35.3 6.5 5.8 0.3 0.3 0.4 0.7 0.0 0.0 0.0 3.5 4.8 6.1 0.0 0.0 0.0 1.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.4 13.5 15.2 17.5 10.0 12.5 10.3 12.4 13.2 4.6 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911019 "Enzymes, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: " "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavourable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavourable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 9.7 11.6 16.5 16.3 21.4 18.5 13.8 24.7 26.1 15.2 20.5 20.0 11.1 21.3 13.6 7.5 48.4 13.6 14.4 14.7 17.0 10.1 11.9 12.4 15.4 16.3 18.1 13.7 11.0 17.3 21.8 22.4 21.1 15.0 14.9 19.8 10.6 20.7 14.3 15.7 35.8 26.9 13.3 13.3 21.6 16.8 9.8 18.7 22.9 15.9 13.6 23.5 14.8 21.3 2.9 1.9 9.8 1.9 3.3 4.5 1.2 22.4 15.0 12.3 12.9 6.7 8.9 17.1 9.1 8.8 13.2 10.2 16.1 23.7 16.6 16.2 9.5 29.0 11.8 14.3 11.5 11.4 9.3 18.2 11.8 10.4 7.6 19.8 24.1 4.9 19.5 12.1 10.5 10.8 15.5 19.1 8.7 27.6 20.7 14.1 14.0 10.9 17.1 9.1 18.3 9.8 18.6 17.0 11.4 15.8 40.4 10.6 29.4 11.8 10.3 14.0 8.8 18.0 10.1 11.6 12.0 16.2 9.5 10.4 11.1 2.7 1.7 4.4 2.9 1.5 4.5 2.3 3.2 3.1 1.9 2.9 2.6 2.4 9.8 3.3 1.9 1.7 1.5 1.2 16.5 21.4 24.7 26.1 17.0 10.1 18.1 13.7 15.0 18.7 MARK3 "CTAK1, KP78, PAR-1A" ENSG00000075413 "Microtubule affinity regulating kinase 3" P27448 14 103385392-103503831 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 14 "eosinophil: 42.2" "Lineage enriched" "Detected in many" 23 "granulocytes: 42.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024652 Approved "HPA024652: AB_1853582" "unprognostic (6.86e-2)" "unprognostic (2.93e-1)" "unprognostic (7.70e-2)" "unprognostic (3.48e-2)" "unprognostic (8.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-3)" "unprognostic (2.21e-1)" "prognostic unfavourable (1.14e-4)" "unprognostic (2.29e-3)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (1.60e-1)" 20.8 31.9 24.6 20.9 29.5 62.7 19.7 59.1 30.2 25.3 20.8 33.2 19.9 17.4 28.5 28.4 24.4 23.1 22.2 33.6 24.9 22.4 20.3 20.1 25.9 20.8 29.6 23.3 24.6 30.7 28.1 30.9 20.5 27.4 19.3 20.0 23.6 18.3 23.1 40.9 19.9 19.2 26.8 20.9 26.8 26.9 24.1 30.3 29.1 25.8 23.1 23.0 20.8 29.0 1.2 1.2 42.2 1.1 0.8 1.8 0.4 13.2 16.1 23.5 17.7 28.2 22.1 20.3 23.6 24.9 28.6 27.5 12.6 20.9 15.8 15.0 22.1 25.0 25.6 25.4 36.4 18.4 11.3 20.4 17.1 15.8 53.2 23.3 13.6 25.6 23.6 23.1 47.4 26.4 21.0 37.0 21.4 35.6 15.9 20.7 17.2 24.3 20.9 24.0 12.7 25.3 28.3 20.7 20.6 25.0 17.2 22.9 23.4 20.0 22.8 15.4 10.9 28.6 21.0 24.0 30.4 19.0 18.7 18.7 20.7 0.4 1.1 42.2 1.1 0.8 0.9 1.2 1.6 1.8 1.1 0.9 1.8 1.4 3.1 0.8 0.7 1.2 1.6 0.4 24.6 29.5 59.1 30.2 24.9 22.4 29.6 23.3 27.4 30.3 MARK4 "FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D" ENSG00000007047 "Microtubule affinity regulating kinase 4" Q96L34 19 45079288-45305283 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039186 Approved Supported Cytosol Cytosol "HPA039186: AB_10796223" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.57e-3)" "prognostic unfavourable (8.31e-8)" "unprognostic (2.02e-1)" "prognostic unfavourable (3.05e-5)" "unprognostic (1.90e-1)" "unprognostic (2.16e-2)" "unprognostic (6.26e-2)" "unprognostic (5.64e-3)" "unprognostic (1.24e-3)" "unprognostic (7.50e-2)" "unprognostic (3.80e-2)" "unprognostic (6.89e-2)" "unprognostic (7.23e-2)" "unprognostic (4.65e-2)" "unprognostic (3.02e-2)" 11.8 13.0 19.4 10.3 26.0 8.4 15.2 21.9 28.6 11.4 10.2 9.0 12.9 6.6 14.0 17.5 13.5 12.9 13.4 14.7 22.2 15.7 8.7 13.5 11.7 10.5 14.3 21.6 21.0 16.8 13.7 12.9 12.1 15.0 12.2 6.3 14.1 12.1 14.2 40.7 20.6 7.5 14.1 10.8 12.4 10.3 32.1 12.3 11.2 10.5 11.5 9.4 13.7 17.9 1.0 2.8 3.5 2.9 1.8 4.3 1.2 8.8 3.8 15.0 10.9 10.7 17.1 4.2 6.6 10.3 9.8 9.2 2.3 5.1 4.3 5.6 12.0 6.0 10.6 9.6 5.5 7.8 8.7 8.5 4.6 8.2 19.7 2.1 7.4 21.2 13.7 8.2 9.5 13.1 10.8 10.7 10.6 7.4 7.5 6.7 6.4 3.3 29.3 4.9 2.8 9.3 7.2 28.1 12.4 9.7 8.6 5.0 4.1 12.4 10.6 8.8 6.7 6.0 4.2 12.0 9.5 4.8 9.4 4.0 7.0 3.5 2.9 0.7 3.4 2.2 0.7 0.9 1.2 4.3 0.8 1.0 2.3 2.6 2.9 1.8 2.0 2.8 2.4 1.2 19.4 26.0 21.9 22.7 22.2 15.7 14.3 21.6 15.0 12.3 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "T-reg: 4.8" "Lineage enriched" "Detected in many" 5 "T-cells: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA017214 Uncertain "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavourable (2.91e-7)" "prognostic unfavourable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavourable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 1.5 1.1 0.3 11.4 0.6 7.7 2.6 0.2 0.8 2.1 5.9 0.3 0.1 4.5 1.2 1.5 12.2 0.4 1.6 1.3 0.5 0.4 1.2 1.3 2.0 8.3 0.4 0.1 0.7 0.8 0.0 0.3 6.3 0.5 0.7 7.8 0.4 2.3 0.1 0.9 2.8 4.6 1.9 1.0 5.2 2.9 11.3 0.4 42.4 0.5 7.2 12.6 1.5 3.3 0.1 0.6 1.0 0.1 0.4 4.8 0.5 35.4 18.2 24.6 14.5 3.4 5.9 14.3 26.3 18.6 36.9 45.6 14.0 14.0 11.9 8.5 12.9 12.2 21.4 16.5 40.8 32.3 8.5 9.3 21.7 13.9 1.3 14.4 11.8 2.1 3.0 28.5 16.2 18.6 11.9 19.0 30.2 11.8 17.9 6.8 19.6 14.3 16.6 16.6 7.6 11.3 12.0 16.7 12.4 14.0 13.5 8.5 11.3 6.9 9.1 19.9 25.2 16.8 23.9 3.7 13.5 17.8 12.6 10.7 27.0 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.6 4.8 0.5 0.3 0.6 0.2 0.8 0.5 0.4 0.4 0.1 0.5 0.4 MKNK1 MNK1 ENSG00000079277 "MAP kinase interacting serine/threonine kinase 1" Q9BUB5 1 46557408-46616843 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 72.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB027355, CAB037310, HPA071293" Approved Supported Nucleoplasm Nucleoplasm "CAB027355: AB_2266303, CAB037310: AB_1854049, HPA071293: " "unprognostic (4.05e-3)" "prognostic favourable (7.05e-4)" "unprognostic (5.28e-2)" "unprognostic (3.47e-2)" "unprognostic (1.64e-1)" "unprognostic (7.38e-2)" "prognostic unfavourable (1.24e-5)" "unprognostic (3.50e-2)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (2.14e-2)" "prognostic unfavourable (1.51e-5)" "unprognostic (7.02e-2)" "unprognostic (3.19e-2)" "unprognostic (4.67e-1)" "unprognostic (5.67e-3)" 17.6 12.0 10.7 16.2 10.5 16.8 12.1 13.7 12.3 9.2 12.6 11.0 9.6 9.7 11.9 13.3 12.2 11.1 11.4 12.3 10.8 7.0 9.4 10.8 16.1 16.3 9.9 9.8 10.7 72.3 8.6 11.3 15.4 11.0 9.9 13.3 11.9 10.6 7.7 12.8 10.2 12.7 13.3 8.1 25.6 11.7 7.6 8.7 12.5 8.8 15.8 10.9 10.9 14.5 4.9 6.0 33.3 12.1 5.0 22.0 6.1 19.3 13.1 8.7 9.6 7.8 11.6 11.6 9.8 9.8 11.9 16.2 15.1 8.0 12.8 12.1 9.8 23.5 14.5 16.0 12.7 21.9 12.9 27.0 15.0 12.9 12.2 14.4 22.0 15.2 11.1 15.5 8.5 13.9 14.1 9.4 6.4 12.7 10.3 12.9 5.9 15.6 9.5 18.2 12.8 12.7 20.3 6.1 5.5 18.9 17.1 15.8 11.5 16.1 11.2 4.3 0.9 13.5 10.9 8.0 13.3 10.9 8.4 18.6 7.9 3.9 12.1 14.3 7.5 11.5 22.0 4.6 6.6 6.8 6.0 4.9 4.8 7.0 33.3 5.0 8.1 4.4 4.4 6.1 10.7 10.5 13.7 12.3 10.8 7.0 9.9 9.8 11.0 8.7 MKNK2 "GPRK7, MNK2" ENSG00000099875 "MAP kinase interacting serine/threonine kinase 2" Q9HBH9 19 2037465-2051244 "Enzymes, Predicted intracellular proteins" "Apoptosis, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.5" "Cell line enhanced" "Detected in all" "HHSteC: 78.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021875, CAB037253, HPA070499" Supported Supported "Nuclear bodies" "Nuclear bodies" "CAB037253: AB_1079401, HPA021875: AB_1854050, HPA070499: " "unprognostic (8.76e-2)" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "prognostic favourable (4.86e-5)" "unprognostic (3.08e-1)" "unprognostic (1.59e-2)" "unprognostic (6.42e-3)" "unprognostic (1.35e-1)" "unprognostic (4.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.08e-1)" "unprognostic (6.56e-2)" "unprognostic (4.07e-2)" "prognostic favourable (4.01e-4)" "unprognostic (1.63e-1)" "unprognostic (1.60e-1)" "unprognostic (1.59e-1)" 30.3 15.6 7.6 24.2 8.5 31.9 31.1 16.6 9.7 12.5 22.7 6.5 21.4 13.1 9.3 18.4 42.1 11.0 21.7 33.3 7.5 5.7 10.3 22.0 24.5 16.9 10.3 3.3 13.8 53.1 8.3 13.4 16.7 9.2 18.8 8.4 14.2 35.2 32.5 207.5 19.3 15.1 13.0 7.0 27.8 16.7 9.1 9.1 16.0 32.3 47.1 32.8 21.2 63.6 10.7 5.9 26.9 8.0 6.1 7.5 2.2 13.1 14.8 6.3 13.8 46.9 17.0 14.2 7.8 5.6 5.6 5.7 9.5 23.1 18.6 10.8 15.7 16.3 7.9 22.8 2.5 25.3 7.4 7.5 12.5 10.1 78.8 14.7 13.6 18.1 55.5 10.6 22.6 13.2 12.9 33.3 3.8 7.7 8.8 12.3 16.5 16.2 16.9 1.8 23.5 9.9 8.6 8.7 10.4 18.3 27.1 33.4 11.2 18.3 19.8 2.0 8.0 8.2 9.3 54.3 21.0 18.2 16.5 11.1 3.7 2.7 6.1 5.7 5.6 6.3 5.1 10.7 5.8 6.2 4.8 10.2 3.7 4.5 26.9 6.1 8.0 5.9 7.5 2.2 7.6 8.5 16.6 9.7 7.5 5.7 10.3 3.3 9.2 9.1 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884331 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 191.1" "Cell line enhanced" "Detected in many" "BJ: 36.5;BJ hTERT+: 55.2;fHDF/TERT166: 45.0;HBF TERT88: 29.0;RPTEC TERT1: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "basophil: 3.6;classical monocyte: 1.3;myeloid DC: 2.8;neutrophil: 4.5;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 13 "dendritic cells: 2.8;granulocytes: 4.5;monocytes: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" 3000000 "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: " "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavourable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavourable (4.46e-4)" 14.9 4.9 4.5 19.8 10.9 0.0 14.4 0.8 5.8 77.1 107.3 22.0 93.2 9.4 111.2 48.3 96.0 56.3 40.6 6.6 4.7 3.2 8.3 5.4 13.2 6.5 25.8 2.8 50.2 1.6 0.5 1.1 8.0 16.0 85.1 27.6 6.0 17.6 158.6 1.6 4.8 33.3 191.1 28.8 7.4 38.7 17.4 13.0 0.2 4.1 2.5 3.4 137.1 21.3 0.2 2.8 4.5 1.3 0.0 0.2 17.3 2.5 7.7 2.1 1.3 2.1 0.4 0.9 36.5 55.2 23.6 17.0 1.6 1.4 0.1 8.2 45.0 0.9 0.9 0.3 29.0 0.0 0.1 20.3 0.2 5.0 11.0 0.1 1.9 6.8 0.7 4.6 6.9 1.8 0.2 0.1 17.5 0.3 0.0 0.5 2.2 1.0 2.3 1.2 6.6 59.6 1.4 0.3 1.1 3.7 0.4 0.6 0.2 0.0 6.7 7.2 2.6 1.7 5.9 0.6 0.7 0.0 18.5 0.2 1.8 3.6 1.3 0.3 0.1 0.2 0.0 0.2 0.0 0.0 2.8 0.1 0.2 0.1 4.5 0.0 0.0 2.7 0.1 17.3 4.5 10.9 0.8 5.8 4.7 3.2 25.8 2.8 16.0 13.0 MYLK2 "KMLC, MLCK2, skMLCK" ENSG00000101306 "Myosin light chain kinase 2" Q9H1R3 20 31819308-31834689 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skeletal muscle: 176.1" "Cell line enhanced" "Detected in some" "Karpas-707: 5.2;RH-30: 13.2;RPMI-8226: 10.7" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059704, HPA059890" Enhanced Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA059704: , HPA059890: " "unprognostic (1.74e-2)" "unprognostic (1.87e-1)" "unprognostic (8.84e-2)" "unprognostic (5.27e-2)" "prognostic favourable (4.00e-4)" "unprognostic (5.58e-2)" "unprognostic (1.38e-7)" "unprognostic (2.29e-1)" "unprognostic (2.60e-3)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (7.25e-11)" "unprognostic (2.01e-1)" "unprognostic (3.15e-1)" "unprognostic (2.60e-2)" "unprognostic (2.70e-2)" 1.4 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 176.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.1 18.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.8 0.0 0.0 0.5 0.1 0.0 0.4 0.1 0.3 0.3 0.6 0.4 0.0 0.1 0.1 0.0 0.2 0.2 0.2 0.7 0.3 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 1.0 0.2 5.2 0.1 0.8 0.7 0.4 0.6 0.4 0.7 13.2 10.7 0.1 0.1 0.7 0.6 3.4 0.1 0.0 0.1 0.1 2.6 0.2 1.0 0.6 2.9 0.1 0.9 0.2 0.2 3.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46703369-46790407 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 62.2;skeletal muscle: 20.8;tongue: 31.1" "Cell line enhanced" "Detected in some" "BEWO: 9.5;HEL: 28.5;K-562: 4.4;SK-BR-3: 6.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons and medulla: 6.6" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.8;hippocampal formation: 5.7" "Region enriched" "Detected in some" 5 "hippocampal formation: 5.2" HPA073447 Enhanced Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA073447: " "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 0.7 0.0 1.7 0.1 0.0 0.1 0.2 0.2 0.0 3.8 0.0 0.0 0.1 3.4 2.0 0.8 0.1 62.2 1.5 1.4 0.4 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.5 0.2 6.6 1.0 0.0 0.0 1.3 0.0 20.8 0.0 0.0 0.0 0.3 0.0 0.0 2.9 0.3 0.0 0.1 31.1 1.1 0.1 0.0 1.2 0.9 2.6 0.7 1.2 0.7 0.2 0.0 0.1 0.1 0.1 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 1.5 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.0 6.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.0 2.5 0.7 0.6 0.6 0.4 0.4 0.7 0.5 0.5 0.3 1.2 0.7 0.7 2.6 1.2 0.5 0.9 0.3 0.2 0.7 1.7 0.1 0.2 1.5 1.4 0.1 0.4 6.6 0.3 MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2750966 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 23.6;tongue: 63.6" "Cell line enriched" "Detected in some" 6 "HEL: 12.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: AB_2147922" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.87e-1)" "unprognostic (5.22e-3)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (7.48e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.19e-2)" "unprognostic (4.63e-2)" 0.5 0.3 0.3 0.3 0.4 0.4 0.8 1.4 0.7 0.3 0.3 0.3 0.3 0.1 0.3 0.5 1.0 0.2 0.3 1.0 0.5 0.5 2.6 0.3 0.5 0.3 0.4 0.3 0.3 1.1 0.7 0.7 0.4 0.4 0.4 0.1 0.4 2.4 0.4 23.6 0.8 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 1.0 63.6 1.5 0.5 0.3 0.1 0.8 0.3 0.3 0.9 1.4 0.1 0.3 0.1 0.6 1.1 1.0 1.2 0.6 0.7 1.5 0.5 0.4 0.5 1.0 1.0 1.6 0.8 1.9 0.2 0.4 0.7 0.2 0.6 12.4 0.6 0.1 0.3 0.3 0.6 1.5 0.5 0.1 1.2 0.5 0.1 0.1 0.3 0.5 0.1 1.3 0.2 0.0 0.9 0.0 0.0 0.8 0.3 1.0 0.6 0.3 0.2 0.5 0.4 0.8 0.7 0.5 0.1 0.2 0.4 0.4 0.2 0.1 0.2 0.3 1.2 0.1 0.1 0.1 0.5 0.0 0.3 0.1 0.2 1.4 0.2 0.1 0.6 0.1 0.3 0.9 0.3 0.8 0.1 0.1 0.3 0.4 1.4 0.7 0.5 0.5 0.4 0.3 0.4 0.3 NIM1K "MGC42105, NIM1" ENSG00000177453 "NIM1 serine/threonine protein kinase" Q8IY84 5 43192071-43280850 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 23.7;pituitary gland: 9.7" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 4.4;HDLM-2: 4.8;PC-3: 5.5;U-87 MG: 6.0" "Cancer enriched" "Detected in some" 11 "glioma: 6.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 3.2" "Group enriched" "Detected in many" 10 "dendritic cells: 1.2;T-cells: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007695 Uncertain Approved Cytosol Cytosol "HPA007695: " "unprognostic (7.97e-2)" "unprognostic (9.79e-2)" "unprognostic (8.74e-2)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (4.35e-2)" "unprognostic (1.35e-1)" "unprognostic (4.28e-2)" "unprognostic (8.84e-4)" "unprognostic (1.25e-1)" "unprognostic (1.55e-5)" "unprognostic (2.18e-1)" "unprognostic (2.66e-1)" "unprognostic (6.46e-3)" "unprognostic (4.98e-3)" 1.4 3.5 9.4 1.6 10.9 0.9 1.3 4.9 23.7 1.6 1.4 6.3 0.0 1.1 1.2 1.6 1.6 1.4 1.5 1.8 8.7 7.7 1.4 1.2 3.6 1.2 5.6 5.8 1.2 1.5 1.2 9.7 1.8 6.4 1.4 1.7 1.7 2.3 2.4 2.0 1.8 1.2 1.3 4.9 1.0 3.0 1.4 8.1 0.0 2.7 0.0 1.0 1.1 0.8 0.1 1.2 0.0 0.0 0.2 3.2 0.0 0.2 0.6 0.1 0.1 0.9 0.5 0.0 1.0 3.1 1.1 4.4 0.1 0.0 0.4 0.6 0.8 0.3 0.6 0.0 2.7 4.8 0.3 0.1 0.6 0.2 1.6 0.2 0.6 1.9 0.1 0.5 0.0 0.0 0.2 0.3 0.9 0.2 0.3 0.2 0.0 5.5 0.2 0.3 0.5 0.1 0.7 0.9 0.1 1.7 0.5 0.3 0.4 1.5 0.0 0.9 0.8 0.7 0.7 1.6 0.4 0.3 6.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.2 3.2 0.0 9.4 10.9 4.9 11.6 8.7 7.7 5.6 5.8 6.4 8.1 NUAK1 "ARK5, KIAA0537, NuaK1" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063340-106140033 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;parathyroid gland: 18.6" "Cell line enhanced" "Detected in many" "AF22: 23.0;EFO-21: 23.0;Karpas-707: 16.8;RH-30: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057143 Approved "Nucleoplasm,Nucleoli fibrillar center,Microtubules" "Nucleoli fibrillar center" "Nucleoplasm, Microtubules" "HPA057143: " "unprognostic (4.20e-2)" "unprognostic (8.42e-2)" "unprognostic (3.71e-2)" "prognostic unfavourable (9.83e-4)" "unprognostic (4.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (4.80e-2)" "unprognostic (9.91e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-3)" "prognostic unfavourable (4.27e-4)" "unprognostic (2.31e-1)" "unprognostic (8.70e-2)" "unprognostic (4.47e-2)" 8.2 1.8 4.2 2.0 13.0 0.0 5.5 9.9 20.1 4.6 1.7 24.3 1.1 1.0 5.8 1.6 1.9 3.6 2.7 11.3 5.1 3.3 2.5 2.4 4.9 1.5 8.7 8.4 3.2 1.2 18.6 1.9 2.5 7.6 3.6 2.2 2.3 1.8 3.7 9.4 11.6 1.5 6.3 5.5 1.1 1.5 1.3 9.3 1.1 1.8 1.1 1.4 3.4 3.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.9 3.4 23.0 0.2 9.2 1.0 10.6 5.7 3.9 4.4 3.3 1.7 0.8 0.0 23.0 10.3 4.8 4.8 4.6 2.0 0.0 1.3 0.0 3.6 1.8 1.9 0.0 0.0 4.7 3.1 2.5 0.8 8.3 0.0 16.8 3.1 0.5 0.1 0.2 4.5 1.4 0.0 33.0 4.0 2.5 5.9 2.7 0.1 2.6 0.7 0.2 1.2 0.1 6.2 3.8 12.8 1.4 6.8 0.0 0.0 0.3 1.1 0.0 3.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.2 13.0 9.9 17.5 5.1 3.3 8.7 8.4 7.6 9.3 NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302059-205321791 "Enzymes, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 42.4" "Cell line enhanced" "Detected in many" "BEWO: 24.3;CACO-2: 12.9;RPMI-8226: 18.7;RPTEC TERT1: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in all" "neutrophil: 42.4" "Group enriched" "Detected in all" 4 "B-cells: 15.3;granulocytes: 42.4;T-cells: 10.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA008958 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavourable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favourable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" 1.4 2.8 0.8 12.5 2.4 8.3 0.9 9.2 1.5 18.9 10.4 3.9 2.4 13.6 2.7 3.8 31.3 3.4 1.3 1.1 1.7 1.0 14.5 3.6 16.2 20.3 5.5 1.5 3.3 13.2 0.1 2.3 7.2 2.0 1.5 7.5 9.8 9.7 2.0 0.7 12.9 15.4 0.9 2.7 10.4 2.0 5.6 2.4 5.5 14.5 20.1 31.7 2.8 24.6 15.3 3.6 42.4 5.6 5.7 10.7 5.4 2.2 12.3 7.5 0.3 0.2 0.3 24.3 2.9 3.0 8.1 3.3 12.9 0.4 3.7 1.8 0.8 4.5 1.7 4.4 3.5 0.0 0.2 0.0 0.7 2.2 5.2 0.0 0.0 1.4 3.3 4.7 2.8 0.3 0.5 0.9 1.5 0.5 0.0 0.0 4.8 0.4 0.0 0.5 18.7 22.2 0.0 1.1 0.1 0.8 3.5 0.3 3.6 0.0 0.9 2.9 1.4 0.3 4.6 6.6 1.0 2.3 0.4 0.0 1.1 3.4 5.6 13.2 3.9 4.2 2.8 14.2 4.8 4.6 3.6 15.3 10.7 8.1 42.4 5.7 4.1 1.4 2.8 5.4 0.8 2.4 9.2 1.5 1.7 1.0 5.5 1.5 2.0 2.4 OBSCN "ARHGEF30, KIAA1556, KIAA1639, UNC89" ENSG00000154358 "Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF" Q5VST9 1 228208130-228378874 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Calmodulin-binding, Developmental protein, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 180.2;tongue: 48.4" "Cell line enhanced" "Detected in many" "HeLa: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA021186, HPA065801" Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA021186: AB_1854761, HPA065801: " "unprognostic (8.47e-3)" "unprognostic (1.56e-1)" "unprognostic (9.99e-2)" "prognostic unfavourable (1.64e-4)" "unprognostic (5.30e-3)" "unprognostic (6.36e-2)" "unprognostic (4.54e-3)" "unprognostic (1.82e-1)" "unprognostic (8.81e-2)" "unprognostic (1.93e-2)" "unprognostic (3.38e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-2)" 2.5 0.9 0.5 0.9 4.4 0.6 0.7 3.1 0.6 0.6 0.8 0.5 0.5 0.6 0.8 4.4 2.4 1.0 0.6 21.2 0.5 0.7 1.6 0.5 1.0 1.0 0.5 0.5 1.7 1.4 0.4 2.4 0.5 0.9 1.7 0.3 5.2 2.6 1.1 180.2 1.1 0.8 0.5 0.6 1.4 0.5 0.7 0.6 0.5 2.2 48.4 3.5 0.6 0.7 1.0 1.1 0.1 0.4 0.6 3.2 0.7 2.9 2.8 8.0 4.5 0.2 0.1 5.6 1.5 0.5 1.0 0.9 2.0 2.1 5.7 8.1 0.5 1.0 0.4 1.1 0.2 2.1 5.1 1.9 16.0 0.0 2.0 1.3 6.1 3.0 1.0 0.4 0.2 0.4 5.3 1.3 0.3 5.0 2.0 1.6 8.8 1.7 8.1 0.1 1.3 4.6 1.5 3.0 9.0 0.2 2.9 1.1 8.0 3.7 0.7 0.0 9.3 0.2 0.1 4.7 0.9 1.4 0.0 0.8 2.1 0.1 0.4 0.0 0.9 0.1 0.9 0.5 0.9 0.7 0.9 1.0 3.2 0.5 0.1 0.6 0.1 1.1 0.8 0.7 0.5 4.4 3.1 0.6 0.5 0.7 0.5 0.5 0.9 0.6 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.1;testis: 22.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 24.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA016450, HPA021079" Uncertain Supported Cytosol Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.5 1.1 2.4 10.3 24.1 8.9 3.1 6.3 5.2 2.2 2.1 2.2 2.1 3.8 2.9 6.7 3.1 7.2 3.3 1.1 2.9 2.7 3.7 1.3 3.0 14.5 1.3 1.6 1.9 3.3 4.4 4.9 1.1 3.6 12.1 2.8 4.7 2.7 1.8 2.0 4.9 3.9 1.4 1.6 4.4 3.4 22.0 7.2 9.0 4.8 1.9 9.9 2.7 1.9 7.1 1.1 4.8 1.0 2.7 6.0 3.0 4.9 6.7 9.1 11.5 0.7 1.4 12.1 4.8 1.5 4.4 6.2 5.4 5.0 2.6 1.0 1.1 12.5 10.3 4.1 3.2 10.4 9.7 7.1 12.4 9.6 0.5 9.7 11.2 0.6 3.3 4.6 1.3 3.1 9.2 3.5 3.1 5.6 11.5 10.2 10.1 4.1 18.3 9.2 3.2 1.7 11.2 16.1 4.9 2.8 5.5 2.1 4.6 7.0 4.1 6.1 5.5 7.7 6.4 4.8 4.8 12.2 3.8 7.3 5.6 4.8 1.0 0.7 1.7 0.6 1.5 7.1 5.9 5.3 1.1 6.6 3.7 3.9 1.3 2.7 1.0 0.7 6.0 3.0 2.4 24.1 6.3 5.2 2.9 2.7 1.3 1.6 3.6 7.2 PHKG1 PHKG ENSG00000164776 "Phosphorylase kinase catalytic subunit gamma 1" Q16816 7 56080283-56092996 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 105.6;tongue: 32.9" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in many" 18 "glioma: 23.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012057 Enhanced "HPA012057: AB_1855305" "unprognostic (2.00e-3)" "unprognostic (1.09e-1)" "unprognostic (7.09e-3)" "unprognostic (5.87e-3)" "unprognostic (2.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (6.69e-3)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (9.14e-4)" "unprognostic (1.92e-1)" "unprognostic (7.97e-9)" "unprognostic (6.61e-3)" "unprognostic (2.34e-1)" "unprognostic (1.12e-2)" "unprognostic (3.85e-2)" 2.0 1.5 4.9 0.8 6.1 1.1 1.5 6.0 5.8 0.7 2.6 6.5 0.0 1.0 0.9 1.5 3.2 0.9 1.1 11.8 4.1 2.9 0.6 0.7 0.9 0.8 3.5 3.9 1.0 0.8 1.2 0.6 0.6 6.8 1.4 0.8 0.0 1.6 0.8 105.6 1.6 0.9 1.1 3.6 0.8 0.8 0.7 4.8 0.0 0.6 32.9 1.2 1.8 0.3 1.3 0.6 3.3 0.7 0.3 1.9 0.2 2.9 2.1 0.5 1.7 3.1 5.3 1.4 0.3 0.6 1.0 0.8 0.7 1.3 0.8 0.5 1.0 1.5 1.2 0.2 0.8 0.8 2.1 0.8 2.9 0.7 0.8 1.5 3.2 3.3 2.2 1.6 0.7 0.3 2.2 3.9 0.1 1.3 2.2 5.5 1.0 1.3 1.2 0.3 1.0 0.6 1.9 1.5 1.6 0.3 2.1 0.1 1.1 1.9 0.8 0.5 1.7 4.4 1.1 1.8 0.7 2.2 1.2 1.4 1.0 0.4 0.5 0.0 0.8 0.2 1.9 0.3 1.2 0.3 0.2 1.3 0.6 0.6 3.3 0.3 0.7 0.6 0.5 0.2 4.9 6.1 6.0 5.8 4.1 2.9 3.5 3.9 6.8 4.8 PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748270-30761176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 44.5;testis: 95.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol Cytosol "HPA065618: AB_2685520, HPA068751: AB_2686025" "unprognostic (7.63e-3)" "prognostic favourable (7.90e-4)" "prognostic unfavourable (9.92e-4)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "prognostic favourable (1.90e-4)" "unprognostic (6.45e-2)" "unprognostic (1.25e-2)" "prognostic favourable (8.02e-4)" "unprognostic (6.15e-2)" "unprognostic (5.27e-2)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" 4.3 8.3 8.7 6.9 8.0 15.9 5.8 9.1 12.0 4.7 7.9 7.3 9.0 6.8 5.6 7.8 5.3 6.8 7.2 6.4 9.0 9.3 8.2 11.0 5.8 6.8 8.6 9.2 4.7 5.1 17.3 8.5 6.3 11.8 7.7 7.6 6.4 7.0 9.9 6.4 8.4 7.3 6.3 5.8 6.9 7.2 95.4 7.3 5.5 8.6 5.5 7.7 5.2 4.7 8.8 21.2 44.5 22.7 23.5 16.8 17.6 13.5 8.9 7.5 9.2 7.1 5.7 16.9 9.5 14.3 13.0 14.9 7.7 6.8 11.7 11.3 9.8 13.0 7.8 12.1 10.5 6.3 21.7 6.4 14.8 21.6 10.9 9.9 9.2 7.7 6.6 12.5 5.9 13.2 8.7 6.8 9.4 31.2 11.7 14.6 10.3 10.4 15.8 11.7 15.6 14.9 15.3 10.1 7.0 7.7 21.5 9.1 16.9 8.6 7.8 8.0 8.9 10.0 8.7 13.8 7.5 8.0 15.9 19.4 6.5 14.0 22.7 44.5 16.2 22.4 13.3 8.8 11.6 16.4 21.2 8.5 10.4 12.1 18.2 23.5 15.9 18.2 16.8 17.6 8.7 8.0 9.1 12.0 9.0 9.3 8.6 9.2 11.8 7.3 PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170203-37175426 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 34.8;HMC-1: 64.9;U-698: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 64.6" "Group enriched" "Detected in all" 5 "granulocytes: 64.6;T-cells: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoli,Cytosol Cytosol Nucleoli "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavourable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" 39.3 5.4 7.4 18.5 8.9 80.9 20.1 8.1 9.9 23.0 17.9 4.7 4.2 17.9 15.4 9.8 56.3 21.6 24.7 20.8 8.2 3.7 7.5 24.5 14.5 35.7 7.4 2.2 20.0 9.6 2.0 5.6 28.7 12.7 15.6 8.8 6.9 12.8 4.5 26.5 31.3 26.1 31.6 10.7 21.4 12.1 6.8 7.6 15.0 7.2 20.1 28.8 32.6 31.2 1.7 1.4 64.6 1.7 8.4 19.0 8.5 3.0 1.2 2.0 1.1 4.6 2.4 23.5 1.0 3.3 2.2 3.6 4.5 4.2 6.0 1.7 1.2 3.5 2.0 3.2 2.0 27.5 1.3 34.8 1.3 5.8 4.7 0.6 64.9 8.3 4.0 2.0 1.3 0.6 29.9 9.8 0.3 0.7 1.9 3.1 3.7 1.9 4.6 3.6 7.1 0.6 18.4 9.7 1.9 2.3 0.2 0.6 0.5 1.0 1.1 1.3 3.9 5.8 1.3 4.6 2.4 116.6 0.5 8.8 1.3 64.6 1.7 24.4 14.7 1.6 19.0 1.7 13.1 12.9 1.4 1.3 11.9 9.0 14.1 8.4 0.9 0.4 9.4 8.5 7.4 8.9 8.1 9.9 8.2 3.7 7.4 2.2 12.7 7.6 PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 63.4;lymphoid tissue: 71.2" "Group enriched" "Detected in many" 5 "HDLM-2: 58.9;Karpas-707: 73.0;RPMI-8226: 71.9;U-266/70: 133.0;U-266/84: 117.5" "Cancer enriched" "Detected in all" 6 "testis cancer: 171.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol Cytosol "HPA000285: AB_1079619" "unprognostic (2.34e-3)" "prognostic favourable (4.05e-5)" "unprognostic (8.04e-2)" "unprognostic (7.30e-2)" "unprognostic (6.41e-3)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (5.23e-2)" "unprognostic (2.47e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavourable (1.17e-11)" "unprognostic (3.36e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.38e-2)" 3.6 3.4 4.3 37.2 7.2 30.4 3.4 7.1 7.9 4.5 13.4 2.1 2.2 29.5 2.8 4.3 10.0 5.6 8.3 3.1 5.6 6.7 5.2 5.4 10.6 59.7 3.8 4.6 5.4 3.0 1.0 4.9 2.4 6.7 3.6 17.7 6.1 16.9 4.9 1.5 3.0 19.2 2.2 3.1 71.2 14.7 5.7 1.3 39.4 4.8 3.6 47.9 24.6 3.3 26.0 2.9 46.9 3.0 17.0 63.4 13.2 1.8 1.5 0.8 1.6 0.3 0.2 1.2 1.1 1.4 1.6 1.4 1.4 1.3 7.8 0.5 0.5 1.1 2.6 1.0 1.5 58.9 2.1 9.4 1.6 1.4 0.7 2.2 6.4 0.6 0.9 1.6 1.0 0.5 10.0 73.0 0.9 1.3 0.8 4.7 17.8 2.4 1.0 0.5 71.9 1.6 0.2 0.5 0.8 1.2 0.8 0.8 2.0 3.1 0.3 0.3 0.2 0.3 1.1 133.0 117.5 15.0 1.5 2.0 0.3 46.9 1.5 14.3 12.5 1.9 21.2 26.0 34.4 17.6 2.5 15.9 36.9 23.0 38.3 17.0 3.0 2.9 63.4 13.2 4.3 7.2 7.1 7.9 5.6 6.7 3.8 4.6 6.7 1.3 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960513-49964080 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol Cytosol "HPA068758: " "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavourable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favourable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 32.5 15.5 6.8 19.9 16.7 62.4 50.5 7.6 11.9 16.4 22.6 11.3 20.9 15.9 14.4 17.6 25.0 15.9 37.8 23.6 7.5 7.9 29.1 25.7 38.3 29.4 21.1 4.9 13.9 36.4 4.8 14.9 31.4 15.1 28.4 7.6 9.7 27.6 22.7 39.9 31.3 20.9 12.2 10.1 25.4 33.6 13.0 13.5 9.7 19.1 19.9 19.0 25.6 18.3 6.1 5.7 16.9 4.0 1.2 4.5 1.9 7.2 4.8 3.2 6.1 2.5 1.9 18.5 4.6 7.4 5.4 3.9 8.0 6.2 12.9 5.8 1.2 6.2 6.2 3.4 1.9 9.7 25.7 5.3 11.5 9.6 12.0 11.5 10.3 3.6 11.5 3.3 5.7 17.6 7.3 45.7 1.6 16.2 5.8 20.6 6.8 7.7 27.2 5.4 15.3 2.9 5.5 11.6 8.1 8.9 40.6 28.4 5.3 15.3 4.6 3.4 14.8 5.6 7.4 23.5 14.9 11.0 8.6 6.5 9.2 0.0 3.1 0.1 1.9 3.2 2.3 3.4 4.4 3.8 2.5 6.1 4.1 1.7 16.9 1.2 4.0 5.7 4.5 1.9 6.8 16.7 7.6 11.9 7.5 7.9 21.1 4.9 15.1 13.5 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669730-153689010 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4;seminal vesicle: 38.5" "Cell line enriched" "Detected in some" 8 "AN3-CA: 26.5" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.8 21.4 2.2 35.4 0.6 0.9 3.7 24.9 0.9 21.9 0.9 6.9 3.8 4.2 3.1 14.5 2.9 2.9 3.8 19.5 17.0 1.0 0.5 0.7 0.6 6.1 15.5 0.7 0.5 1.4 0.3 2.4 3.8 12.6 4.2 0.4 0.7 38.5 2.2 1.4 5.2 15.3 2.6 0.7 5.5 4.7 1.7 0.0 0.5 0.0 0.7 10.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 26.5 0.0 0.0 2.8 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.4 0.0 0.0 0.0 3.2 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.1 0.0 0.1 2.1 0.2 0.3 0.0 0.2 1.1 0.0 0.2 0.2 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 35.4 3.7 23.2 19.5 17.0 6.1 15.5 3.8 1.7 PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759379-40798374 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles" "Nuclear speckles" "CAB005050: AB_562037, HPA035409: , HPA064946: " "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-2)" 40.6 15.7 9.4 15.9 16.1 29.0 26.2 14.3 17.7 30.2 24.0 19.9 18.9 21.7 23.5 20.9 22.5 20.4 21.3 15.0 10.5 11.7 35.9 40.7 24.8 16.7 12.2 8.5 28.8 20.6 25.3 20.0 16.8 35.7 26.1 22.3 20.0 23.2 17.9 18.5 16.6 32.6 20.7 14.1 25.1 22.1 29.3 11.4 21.4 28.0 20.5 22.9 32.5 17.9 8.4 6.5 15.9 8.9 10.8 12.6 6.5 11.3 11.8 9.5 12.6 23.5 24.5 9.0 19.3 19.8 14.5 13.0 11.1 14.7 6.7 9.0 19.8 9.2 8.7 17.6 27.5 19.6 7.9 13.3 27.3 8.8 19.4 12.6 14.0 22.6 8.6 19.4 20.0 21.4 6.2 19.4 21.6 5.4 11.6 9.9 4.1 14.3 9.8 20.3 9.8 22.3 19.3 8.2 8.3 33.9 22.6 11.5 11.9 10.5 22.9 26.2 14.2 15.1 15.7 7.7 6.0 8.0 16.4 27.4 13.9 14.1 6.6 12.7 10.0 8.1 12.6 8.4 9.4 9.4 6.5 7.7 11.5 10.0 15.9 10.8 8.9 2.0 11.3 6.5 9.4 16.1 14.3 17.7 10.5 11.7 12.2 8.5 35.7 11.4 PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645322-56715335 "Enzymes, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 40.2" "Cell line enhanced" "Detected in many" "HEK 293: 8.5;RPTEC TERT1: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" "Nuclear speckles" "Golgi apparatus" "HPA044540: " "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavourable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavourable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favourable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" 2.4 2.1 3.7 1.2 6.3 0.7 4.1 7.2 8.1 2.2 5.5 1.2 2.4 1.2 3.0 3.2 6.3 3.5 2.6 39.1 4.2 2.9 14.5 1.4 2.0 0.8 2.4 6.2 2.5 2.6 10.4 2.6 1.2 5.0 4.6 2.2 6.0 4.5 3.5 40.2 1.4 2.1 7.2 1.9 1.9 3.2 1.7 0.8 0.0 4.0 12.3 0.8 4.4 2.1 0.2 0.0 1.0 0.1 0.1 0.1 0.0 0.0 3.7 2.0 0.0 0.7 0.5 2.3 1.8 1.4 2.5 4.3 3.8 4.7 0.0 0.6 0.6 0.0 7.8 0.0 7.1 0.0 8.5 0.0 6.9 5.2 0.0 0.0 0.1 0.6 0.0 3.5 0.3 0.8 0.0 0.0 1.0 0.1 0.0 0.0 5.5 5.4 0.0 0.0 0.0 14.0 1.2 2.0 5.4 5.7 0.1 0.0 3.2 0.0 0.0 1.5 2.3 2.7 6.3 0.0 0.0 0.0 4.5 0.0 1.1 0.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 3.7 6.3 7.2 8.1 4.2 2.9 2.4 6.2 5.0 0.8 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 17.8;fHDF/TERT166: 19.0;HSkMC: 17.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favourable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavourable (2.91e-4)" "unprognostic (3.89e-1)" 7.4 10.6 8.0 5.3 9.7 0.7 19.0 4.9 8.9 5.1 8.7 5.1 24.1 3.1 8.3 9.0 3.5 6.8 9.0 6.3 9.8 5.9 15.1 2.3 14.9 1.6 5.6 6.6 15.7 7.3 35.7 9.2 4.5 10.8 20.1 3.5 4.9 3.5 24.4 3.1 2.7 3.5 19.7 16.4 2.4 4.8 16.1 8.6 0.5 8.2 2.9 1.8 14.1 12.2 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.6 4.0 17.8 16.7 0.1 12.1 9.3 12.4 6.7 0.0 0.5 0.0 1.2 19.0 0.1 5.9 1.4 6.8 0.0 4.1 0.0 0.1 0.4 9.0 0.0 0.1 17.7 0.6 0.8 1.4 2.5 1.2 0.4 11.6 1.3 0.0 0.0 2.5 6.2 0.0 7.0 3.2 13.2 5.6 3.6 7.1 2.1 0.0 4.7 0.0 0.1 6.3 11.7 4.8 1.0 3.5 0.0 0.0 0.0 3.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 8.0 9.7 4.9 8.9 9.8 5.9 5.6 6.6 10.8 8.6 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favourable (9.15e-4)" 17.1 7.6 7.0 25.8 6.5 18.1 18.0 2.5 6.8 16.8 13.7 5.8 18.7 13.7 14.8 16.5 23.4 15.6 17.4 7.4 6.3 3.1 13.2 9.1 21.3 24.8 7.5 2.7 17.0 12.5 10.3 17.2 20.1 6.6 14.8 7.7 11.9 15.6 21.5 7.5 26.8 19.8 11.7 6.8 34.8 15.2 6.6 7.2 41.5 18.7 10.5 33.0 17.4 37.5 6.6 0.4 7.3 1.0 2.9 6.1 1.9 8.6 13.4 5.3 6.5 4.4 3.6 6.8 4.5 7.1 9.4 10.3 7.4 8.5 10.1 7.9 6.0 12.9 4.7 12.0 2.9 8.6 7.0 10.6 4.2 3.9 5.8 7.7 15.7 4.3 5.8 5.4 4.6 16.5 6.8 14.6 3.9 9.1 14.8 25.0 4.5 6.8 9.7 2.5 16.3 5.8 12.9 3.4 10.8 8.4 7.0 1.8 5.6 3.1 7.8 4.0 8.0 3.4 3.6 14.3 56.9 5.0 4.2 6.4 4.2 0.9 1.0 3.4 5.6 0.9 4.9 6.1 5.7 6.1 0.4 6.6 5.1 4.9 7.3 2.9 0.7 0.0 4.0 1.9 7.0 6.5 2.5 6.8 6.3 3.1 7.5 2.7 6.6 7.2 PRKD3 "EPK2, PRKCN" ENSG00000115825 "Protein kinase D3" O94806 2 37250502-37324808 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029529 Uncertain Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA029529: AB_10602082" "unprognostic (1.39e-1)" "unprognostic (7.34e-2)" "prognostic favourable (4.84e-4)" "unprognostic (1.23e-2)" "unprognostic (5.61e-2)" "unprognostic (2.08e-1)" "prognostic unfavourable (3.47e-4)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (2.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.81e-1)" "unprognostic (7.62e-3)" "unprognostic (2.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" 16.1 22.1 9.5 20.7 10.7 5.3 35.1 4.8 9.2 17.2 18.0 7.2 7.2 6.0 19.2 16.0 9.8 11.3 10.0 11.6 12.7 6.1 9.9 8.4 20.4 22.3 11.4 3.7 15.0 7.6 12.9 20.7 11.1 10.3 14.4 8.3 27.8 11.1 13.3 19.1 11.5 12.1 16.5 15.4 22.0 10.5 16.8 10.8 16.2 11.8 9.3 21.2 12.4 17.7 16.4 8.2 5.7 8.3 6.3 11.5 3.4 12.6 5.4 14.3 11.8 10.9 18.4 10.5 8.2 15.3 9.3 9.5 8.6 4.5 18.6 6.9 12.3 5.0 9.7 10.1 12.6 24.0 14.2 12.2 8.3 5.8 4.5 8.7 7.5 8.6 5.2 14.7 9.7 16.5 10.2 22.9 10.8 2.1 3.8 6.8 15.1 5.2 12.8 22.6 15.9 6.2 14.3 10.8 28.0 7.9 4.5 48.2 4.9 8.0 15.9 26.7 13.9 10.6 9.2 26.2 48.5 21.7 9.3 3.7 16.0 5.7 8.3 5.5 10.5 6.6 9.1 12.4 8.8 8.4 7.8 16.4 10.4 11.5 1.5 6.3 3.3 8.2 4.1 3.4 9.5 10.7 4.8 9.2 12.7 6.1 11.4 3.7 10.3 10.8 PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893272-67929678 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053927 Approved Approved Nucleoplasm Nucleoplasm "HPA053927: AB_2682312" "unprognostic (2.57e-2)" "unprognostic (8.91e-3)" "unprognostic (1.88e-1)" "unprognostic (5.79e-2)" "unprognostic (3.26e-1)" "unprognostic (3.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-2)" "unprognostic (9.85e-3)" "unprognostic (8.32e-2)" "prognostic favourable (4.28e-10)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (4.15e-2)" "unprognostic (3.90e-3)" 14.3 18.3 13.6 14.0 16.6 4.8 15.1 13.3 13.3 11.0 14.7 17.7 24.0 14.0 19.2 14.6 17.7 20.2 19.3 17.8 12.2 8.4 18.8 15.1 13.1 10.4 16.2 12.7 21.2 35.3 33.2 13.0 9.8 16.1 14.3 11.4 16.2 19.0 14.8 19.9 14.0 15.2 16.3 11.3 12.8 19.1 31.7 15.0 12.5 14.9 12.9 8.6 14.8 18.7 4.0 5.2 4.5 5.8 5.2 5.6 3.5 7.3 13.1 14.9 16.5 23.3 11.8 9.7 8.8 13.5 9.4 8.4 9.9 10.6 6.9 13.5 14.9 11.2 8.6 9.1 3.2 2.7 9.6 7.9 9.7 12.5 16.0 7.5 4.8 21.7 15.8 11.1 11.8 13.7 12.0 3.0 9.7 16.4 10.2 4.8 14.3 8.2 15.7 5.7 14.3 11.1 9.2 13.0 15.5 27.4 7.5 9.0 13.8 13.7 12.0 10.6 3.8 8.8 4.4 9.1 4.8 14.9 12.8 5.1 11.6 0.0 4.3 4.5 5.6 5.8 3.8 4.0 3.9 5.3 5.2 3.5 3.4 4.3 2.7 5.2 3.6 3.8 2.3 3.5 13.6 16.6 13.3 13.3 12.2 8.4 16.2 12.7 16.1 15.0 PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86048373-86088621 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "kidney: 1.9;placenta: 1.2;testis: 2.0" "Cell line enriched" "Detected in single" 18 "HEL: 13.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015095, HPA056839" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: AB_1855815, HPA056839: " "unprognostic (1.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 SIK1 "msk, SNF1LK" ENSG00000142178 "Salt inducible kinase 1" P57059 21 43414483-43427189 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Cell cycle, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 34.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 16.7;HeLa: 27.8;hTCEpi: 21.5;LHCN-M2: 21.6;U-266/84: 15.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 2.0;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 10 "B-cells: 2.0;dendritic cells: 1.6" "CAB023801, HPA038211, HPA078064" Approved Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB023801: , HPA038211: , HPA078064: " "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (3.31e-3)" "unprognostic (3.00e-1)" "unprognostic (5.02e-2)" "unprognostic (7.97e-3)" "unprognostic (1.51e-1)" "unprognostic (7.30e-3)" "unprognostic (2.35e-3)" "unprognostic (4.97e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-1)" "unprognostic (3.89e-1)" "unprognostic (9.94e-3)" "unprognostic (3.88e-2)" "unprognostic (2.89e-1)" "unprognostic (1.82e-1)" 8.8 2.3 3.0 3.6 3.0 5.9 7.5 3.0 3.0 13.5 3.0 3.0 3.0 0.0 3.0 3.0 12.9 5.5 10.7 7.1 3.0 0.8 3.0 12.3 5.4 3.0 3.0 3.0 13.7 7.3 3.5 5.7 8.2 3.0 3.9 0.1 3.0 4.6 9.8 5.0 34.5 3.0 3.3 3.0 4.0 5.3 3.0 3.0 3.0 3.9 3.0 3.0 10.5 6.1 2.0 1.6 0.0 0.1 0.0 0.1 0.1 0.5 1.7 2.0 0.0 0.1 0.8 0.7 0.9 0.3 1.6 1.3 2.4 0.0 2.4 0.7 0.2 11.1 1.6 16.7 1.0 0.1 0.5 0.7 27.8 0.9 2.3 0.7 0.1 1.0 21.5 0.4 5.1 0.3 0.1 0.5 21.6 0.1 0.4 1.7 0.8 1.5 0.0 0.3 2.5 1.9 6.3 0.0 0.0 10.9 1.8 0.4 1.1 0.3 3.7 0.4 2.0 0.1 0.0 4.3 15.7 0.4 4.6 2.0 0.4 0.0 0.1 0.0 0.1 0.0 0.1 2.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 3.0 3.0 3.0 3.0 3.0 0.8 3.0 3.0 3.0 3.0 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602391-111730853 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016026 Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA016026: AB_1857321" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favourable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favourable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 32.8 10.7 10.1 6.6 17.2 4.0 22.5 10.6 17.3 10.0 9.9 15.1 5.2 7.7 9.5 7.0 7.9 9.7 12.7 14.5 10.5 10.3 14.6 24.4 13.6 5.4 9.7 9.9 16.4 37.8 22.0 28.6 7.5 11.9 8.4 8.3 14.9 15.4 8.6 35.1 8.7 7.7 8.7 9.6 5.8 19.6 4.2 13.0 4.4 11.1 7.9 5.8 8.6 10.0 2.2 2.7 2.8 3.6 2.2 3.5 2.1 5.8 3.9 6.8 7.3 34.0 10.1 4.0 5.1 7.3 3.9 4.5 13.1 6.2 4.6 7.1 5.9 8.3 5.3 3.8 5.1 3.4 2.2 5.0 3.4 6.4 7.4 4.8 3.3 9.8 5.7 5.7 7.4 4.6 4.6 6.7 6.1 2.7 5.0 4.4 2.3 3.9 6.7 7.3 5.5 8.7 5.3 3.2 7.5 7.5 3.1 3.0 7.5 3.9 6.4 8.6 5.2 5.5 7.0 1.9 1.5 9.7 2.8 6.8 5.8 1.1 3.3 2.8 3.5 3.6 1.9 2.0 2.5 2.5 2.7 2.2 1.4 2.0 1.4 2.2 2.9 1.5 2.4 2.1 10.1 17.2 10.6 16.4 10.5 10.3 9.7 9.9 11.9 13.0 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 50.8;TIME: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favourable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favourable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 31.5 8.8 9.8 13.1 14.4 41.0 22.6 34.5 21.1 17.6 14.4 7.9 5.9 12.8 20.9 10.5 16.2 11.5 16.4 13.9 11.0 11.0 16.8 20.3 24.7 19.8 11.4 10.6 15.1 18.0 18.4 16.2 26.2 22.5 12.1 9.9 14.7 10.7 9.4 12.5 24.5 17.0 18.7 9.8 25.4 11.2 13.9 7.2 48.4 24.8 13.5 14.4 15.8 19.3 3.2 3.0 20.9 5.5 8.1 10.7 6.5 3.2 2.0 3.7 3.5 11.1 4.0 3.5 3.5 5.9 3.8 3.8 2.7 4.7 5.1 2.8 4.4 2.1 4.3 7.5 4.0 5.9 3.5 5.9 3.7 3.1 5.8 6.6 6.6 4.4 5.2 4.3 7.4 50.8 2.6 6.0 3.5 1.7 6.6 5.8 4.1 9.1 4.6 2.7 5.4 9.9 5.6 2.6 5.5 3.0 3.3 4.2 2.2 8.4 29.5 3.4 3.4 3.9 4.1 9.7 6.9 4.4 2.4 7.9 4.8 4.8 2.8 5.4 7.6 5.5 10.7 2.8 6.7 7.6 3.0 3.2 10.1 10.1 20.9 8.1 5.0 0.9 7.1 6.5 9.8 14.4 34.5 21.1 11.0 11.0 11.4 10.6 22.5 7.2 SPEG "APEG1, BPEG, KIAA1297, MGC12676, SPEGalpha, SPEGbeta" ENSG00000072195 "SPEG complex locus" Q15772 2 219434846-219498287 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 88.7" "Cell line enhanced" "Detected in many" "U-138 MG: 14.7;U-2 OS: 15.0;U-251 MG: 13.7;U-87 MG: 16.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 7.7 7.1 10.1 9.1 7.7 1.2 4.2 10.4 9.8 19.2 45.1 4.1 10.5 5.7 31.6 14.1 13.5 19.0 17.4 17.8 8.7 5.3 2.0 1.4 3.0 1.7 4.0 8.0 7.0 2.9 4.7 10.5 4.8 5.5 16.7 4.5 6.7 7.8 23.0 88.7 2.2 9.2 45.2 9.1 1.9 16.1 3.0 3.9 0.0 2.0 16.8 1.6 22.5 12.6 0.0 0.3 0.0 0.0 0.0 0.5 0.7 4.0 0.3 2.1 3.5 1.1 3.2 1.4 8.7 5.8 5.8 4.4 3.1 1.4 0.0 3.2 6.4 5.1 1.7 2.0 2.3 0.5 1.3 0.4 3.7 0.2 1.5 0.0 0.7 9.3 3.1 5.3 1.3 0.0 3.0 0.0 4.2 1.1 0.1 12.4 4.4 1.6 2.1 4.7 0.7 5.7 0.0 2.3 10.9 0.6 0.0 0.1 0.3 0.1 0.1 14.7 15.0 1.7 13.7 0.5 0.0 0.1 16.6 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.7 10.1 7.7 10.4 9.8 8.7 5.3 4.0 8.0 5.5 3.9 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228435 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: " "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favourable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favourable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 13.4 13.7 13.5 11.8 12.4 19.3 16.7 17.8 16.0 12.2 16.1 8.3 19.8 18.1 10.8 8.7 15.1 10.0 11.8 15.3 12.6 9.8 10.7 22.1 9.4 12.5 9.7 10.4 11.0 16.8 10.7 11.6 12.2 9.9 12.2 5.3 11.9 16.0 12.2 49.2 16.8 18.0 7.7 7.6 16.9 15.5 59.8 7.5 11.8 12.4 14.5 19.0 11.4 9.8 2.7 1.9 11.7 6.3 1.9 1.8 0.5 21.1 10.2 7.8 14.7 7.4 6.7 16.5 10.3 10.8 9.7 10.4 8.3 14.8 13.9 11.5 10.8 13.7 7.6 15.9 3.0 25.9 18.7 14.2 0.6 10.5 15.9 14.2 23.8 12.2 11.6 7.5 11.1 9.7 26.5 19.1 5.5 15.8 13.7 14.4 14.9 12.6 21.7 8.3 15.5 8.8 15.5 18.1 13.0 0.0 7.7 11.1 12.1 23.4 13.1 10.1 11.4 19.7 16.4 37.6 15.8 10.4 10.0 19.0 10.3 2.0 4.2 4.5 0.6 6.0 0.4 2.7 1.0 1.8 1.9 1.0 1.0 0.9 11.7 1.9 6.3 1.0 0.7 0.5 13.5 12.4 17.8 16.0 12.6 9.8 9.7 10.4 9.9 7.5 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43626786 "Enzymes, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 43.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "HPA018138, HPA037979" Uncertain Approved "Nuclear speckles,Plasma membrane" "Nuclear speckles" "Plasma membrane" "HPA018138: , HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 7.1 10.1 6.1 43.3 8.2 20.2 8.4 7.9 7.2 4.8 9.3 3.7 2.0 6.1 5.3 4.2 10.1 4.7 8.6 17.7 5.7 5.6 6.7 8.1 15.2 36.6 6.6 2.6 7.3 14.3 1.5 6.3 37.2 5.7 6.2 5.3 3.6 8.6 3.4 10.7 4.8 12.3 5.8 5.3 27.8 11.0 9.0 2.8 30.1 7.3 6.8 37.7 10.3 8.1 10.8 1.4 11.5 0.9 12.7 11.4 2.9 4.5 5.7 5.2 3.5 6.5 8.6 2.1 16.5 17.8 9.0 9.2 4.9 3.3 7.3 26.0 13.7 9.4 3.9 21.9 12.6 18.0 4.4 6.5 4.3 6.1 4.8 11.2 4.4 7.0 25.8 11.9 10.9 16.8 7.6 25.2 10.3 2.1 18.2 5.2 8.0 18.7 6.3 3.3 14.5 15.7 3.4 2.8 6.3 7.4 3.4 4.8 4.0 5.7 16.8 19.6 7.5 11.6 18.4 15.3 7.6 10.6 19.9 9.9 31.2 0.7 0.4 11.5 5.8 0.2 5.8 10.8 6.1 9.7 0.3 10.1 11.4 10.2 6.4 12.7 0.9 1.4 3.2 2.9 6.1 8.2 7.9 5.9 5.7 5.6 6.6 2.6 5.7 2.8 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133566-196176503 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 62.0;bone marrow: 103.4;lymphoid tissue: 72.2" "Cell line enhanced" "Detected in many" "Daudi: 35.5;HMC-1: 36.0;Karpas-707: 33.4;U-698: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebellum: 71.1" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavourable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 21.0 4.1 3.2 42.8 3.8 103.4 10.1 3.2 3.3 8.2 18.8 1.1 3.8 8.5 3.4 3.9 8.9 6.3 8.6 5.7 3.3 2.2 7.2 2.9 26.2 53.7 2.3 1.8 3.1 5.0 0.7 3.8 6.5 1.7 6.8 5.7 3.5 16.7 6.1 3.4 10.9 31.8 5.3 2.7 59.3 6.0 4.6 1.4 72.2 7.5 7.0 56.2 11.3 6.0 16.9 13.6 62.0 27.0 10.3 28.4 19.0 3.1 2.2 3.3 1.2 14.7 5.6 3.7 7.6 11.4 8.3 8.7 6.6 1.1 35.5 7.0 4.3 2.2 1.4 3.2 10.2 6.2 3.8 3.3 2.8 0.6 4.4 13.4 36.0 7.1 3.2 10.3 5.4 3.4 2.6 33.4 20.6 1.7 17.4 30.4 1.9 5.1 2.9 20.3 10.7 4.9 7.5 1.2 1.3 1.9 1.9 1.6 1.3 7.0 4.1 8.1 4.0 5.8 4.2 13.7 22.2 38.7 6.1 4.6 3.6 35.9 19.7 40.2 12.0 20.7 15.3 13.3 21.5 14.5 13.6 16.9 28.4 23.1 62.0 10.3 27.0 9.7 18.5 19.0 3.2 3.8 3.2 3.3 3.3 2.2 2.3 1.8 1.7 1.4 STK33 ENSG00000130413 "Serine/threonine kinase 33" Q9BYT3 11 8391868-8594289 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.4" "Cell line enhanced" "Detected in many" "Daudi: 14.1;HEK 293: 12.0;Karpas-707: 13.2;SCLC-21H: 14.8;U-251 MG: 14.9;U-266/84: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 7.1;naive B-cell: 4.4" "Lineage enriched" "Detected in many" 5 "B-cells: 7.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015742, HPA056855" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "HPA015742: AB_1857592, HPA056855: " "unprognostic (2.57e-2)" "unprognostic (2.80e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (3.57e-1)" "unprognostic (1.40e-1)" "unprognostic (7.28e-2)" "unprognostic (3.85e-4)" "unprognostic (1.23e-1)" "unprognostic (8.06e-2)" "unprognostic (1.33e-3)" "unprognostic (9.46e-2)" "prognostic favourable (4.89e-6)" "unprognostic (2.39e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.90e-2)" 0.9 6.1 4.7 1.6 7.5 1.1 0.6 6.1 4.4 5.4 5.3 6.8 7.7 2.6 9.6 15.3 2.3 30.7 4.5 11.4 6.6 6.1 7.7 0.4 5.3 2.3 4.9 2.7 10.3 4.6 20.4 29.9 0.3 17.7 5.3 1.3 14.8 1.6 8.9 2.6 0.3 2.5 7.0 6.7 1.2 4.4 34.4 4.6 4.5 14.6 1.5 1.8 3.7 1.4 7.1 0.7 0.0 0.0 0.2 1.4 0.3 0.0 2.0 9.8 0.0 0.0 0.0 0.0 1.7 1.9 4.2 3.9 1.2 0.0 14.1 7.4 0.3 0.0 4.3 1.3 3.7 0.0 12.0 0.0 2.6 3.3 1.6 7.8 0.0 0.4 0.0 0.1 0.0 0.3 0.0 13.2 0.1 0.0 0.3 0.0 7.0 0.0 5.3 1.3 8.9 3.8 0.0 14.8 3.9 0.0 0.0 0.1 0.0 0.8 0.0 0.0 6.7 0.1 14.9 3.1 12.5 0.2 4.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.1 0.0 1.4 0.0 4.4 0.0 1.1 0.0 0.2 0.0 0.7 0.2 0.3 4.7 7.5 6.1 4.4 6.6 6.1 4.9 2.7 17.7 4.6 STK40 "MGC4796, SgK495" ENSG00000196182 "Serine/threonine kinase 40" Q8N2I9 1 36339624-36385896 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 19.2" "Group enriched" "Detected in all" 5 "granulocytes: 19.2;monocytes: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008026 Uncertain Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA008026: AB_1857603" "unprognostic (3.32e-1)" "unprognostic (3.00e-1)" "unprognostic (6.47e-2)" "unprognostic (4.55e-1)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (2.69e-3)" "unprognostic (6.09e-2)" "unprognostic (2.09e-1)" "unprognostic (5.96e-2)" "prognostic favourable (5.59e-4)" "unprognostic (1.19e-1)" "unprognostic (2.75e-2)" "unprognostic (7.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" 22.9 7.2 9.8 15.3 9.4 9.2 26.5 8.9 11.1 10.2 19.1 7.4 16.7 9.4 11.8 12.2 22.3 11.3 18.2 25.6 10.0 7.1 14.3 23.5 16.6 15.4 13.1 7.4 22.2 34.4 9.2 14.7 19.2 12.1 15.7 9.1 9.0 25.1 17.7 53.9 17.2 10.8 26.0 10.3 17.2 17.0 32.0 8.9 9.2 14.6 20.7 16.6 19.5 26.6 2.4 2.7 19.2 8.5 1.6 2.9 2.4 7.0 3.1 15.6 16.2 11.1 6.4 8.8 7.2 9.8 8.7 9.4 17.1 10.2 30.0 5.9 6.7 7.1 14.2 3.1 6.4 13.0 11.1 19.6 2.9 21.8 11.0 11.4 26.2 5.8 11.8 6.7 3.5 5.4 24.0 10.9 5.4 11.1 11.8 15.1 10.0 4.3 13.6 10.6 19.9 5.4 8.0 19.1 9.7 5.5 8.7 23.9 5.9 13.5 9.0 5.5 11.5 16.1 15.8 11.4 6.4 25.3 28.6 10.0 18.0 1.0 3.0 4.9 2.6 6.7 2.9 2.3 1.7 1.7 2.7 2.4 1.0 1.5 19.2 1.6 8.5 2.6 1.0 2.4 9.8 9.4 8.9 11.1 10.0 7.1 13.1 7.4 12.1 8.9 TRIB1 "C8FW, GIG2, TRB1" ENSG00000173334 "Tribbles pseudokinase 1" Q96RU8 8 125430321-125438405 "Enzymes, Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.2;thyroid gland: 90.7" "Cell line enhanced" "Detected in many" "HEL: 54.0;U-266/70: 33.1;U-266/84: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 10.8;neutrophil: 5.8;non-classical monocyte: 3.7;T-reg: 3.1" "Group enriched" "Detected in many" 11 "granulocytes: 10.8;monocytes: 3.7;T-cells: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063982 Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA063982: " "unprognostic (1.90e-3)" "unprognostic (1.45e-1)" "unprognostic (8.80e-3)" "unprognostic (1.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.57e-2)" "unprognostic (4.12e-2)" "unprognostic (1.62e-2)" "unprognostic (6.81e-3)" "unprognostic (9.36e-2)" "unprognostic (2.97e-3)" "unprognostic (1.94e-1)" "unprognostic (1.04e-2)" "unprognostic (5.55e-2)" "unprognostic (2.08e-2)" 26.7 6.5 5.9 17.6 6.5 84.2 13.3 4.3 6.1 10.4 12.4 4.4 6.6 4.9 6.2 6.7 10.9 10.9 21.0 11.1 4.3 4.0 16.6 63.5 28.9 14.6 4.2 3.9 6.4 23.6 20.9 7.2 15.5 4.5 12.1 13.3 15.0 14.5 9.1 22.3 10.4 16.9 11.3 3.1 15.9 18.5 5.6 3.1 9.2 90.7 17.6 12.1 12.4 9.0 0.2 0.5 10.8 3.7 0.0 3.1 0.1 4.0 4.6 0.6 1.3 1.3 2.6 7.3 2.6 3.7 1.9 0.6 6.2 5.4 7.4 2.5 1.9 3.1 2.0 2.6 1.7 3.2 9.7 54.0 2.0 12.0 3.4 27.0 4.9 2.5 3.9 8.1 18.4 5.7 4.7 23.5 0.2 4.3 2.5 4.2 4.5 9.0 5.1 0.9 8.0 15.9 15.5 3.9 1.4 6.5 7.1 25.7 1.8 1.3 2.9 2.1 2.8 2.1 3.3 33.1 33.0 10.3 3.8 0.1 5.0 0.0 0.9 10.8 0.0 1.2 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 5.8 0.0 3.7 0.3 3.1 0.1 5.9 6.5 4.3 6.1 4.3 4.0 4.2 3.9 4.5 3.1 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 40.2;HEL: 39.4;K-562: 53.6;SK-MEL-30: 39.1;WM-115: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 24.8" "Group enriched" "Detected in many" 9 "B-cells: 7.1;NK-cells: 9.5;T-cells: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 19.6 30.9 13.2 17.7 13.3 7.0 23.2 23.2 23.0 10.8 12.3 10.5 6.7 8.7 23.0 22.6 8.1 11.6 14.5 18.2 15.0 10.8 24.8 10.6 18.9 33.0 13.4 16.2 52.3 14.4 6.6 11.3 23.0 15.5 16.3 6.9 35.7 9.9 13.6 6.9 8.2 11.9 17.6 10.4 38.9 19.5 13.9 10.1 37.3 12.1 6.2 33.4 21.9 23.2 7.1 0.6 1.5 0.1 9.5 24.8 4.5 0.0 0.0 30.6 40.2 11.0 10.2 0.0 1.7 1.6 1.0 1.7 0.1 3.3 3.4 1.2 3.6 0.5 2.2 3.4 0.9 3.8 6.3 39.4 0.1 0.5 13.7 2.2 15.1 9.4 3.5 4.4 1.2 4.8 53.6 0.0 1.7 0.3 5.0 9.4 14.5 3.9 0.0 10.2 1.4 7.0 5.0 26.4 12.6 0.2 1.6 39.1 0.0 0.2 3.0 14.6 7.3 0.1 3.8 0.0 0.0 4.9 7.8 7.7 53.8 0.8 0.1 1.5 7.3 0.0 8.8 5.3 14.4 7.7 0.6 7.1 8.5 5.2 0.3 9.5 0.1 0.0 24.8 4.5 13.2 13.3 23.2 23.0 15.0 10.8 13.4 16.2 15.5 10.1 TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 39.0;salivary gland: 47.5" "Cell line enhanced" "Detected in many" "HHSteC: 87.0;hTCEpi: 53.9;hTERT-HME1: 62.7;SK-MEL-30: 79.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm Nucleoplasm "HPA015272: AB_1858269, HPA055442: " "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.25e-3)" "unprognostic (1.92e-1)" "prognostic unfavourable (1.70e-4)" "prognostic unfavourable (6.75e-5)" "unprognostic (1.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "prognostic unfavourable (2.07e-13)" "unprognostic (7.62e-2)" "unprognostic (2.79e-2)" "unprognostic (2.31e-1)" "unprognostic (4.05e-3)" 4.8 8.7 1.6 2.8 1.5 9.7 6.0 3.8 4.2 2.5 1.8 1.2 3.6 1.0 2.1 3.1 9.8 1.1 2.7 3.0 1.4 2.0 3.3 39.0 8.2 7.3 1.0 2.4 4.4 13.8 2.0 10.5 6.2 1.6 3.9 1.6 3.7 47.5 5.3 1.5 6.5 2.5 1.3 0.7 7.9 4.4 2.7 0.6 6.7 27.2 4.1 7.0 2.7 5.3 15.5 4.7 3.3 4.4 6.6 11.4 5.1 10.9 5.5 0.7 1.6 1.9 2.5 4.7 3.2 8.7 3.1 6.5 11.5 5.4 4.7 3.2 2.9 8.8 3.0 14.6 2.9 1.7 2.1 3.6 1.2 18.7 87.0 9.2 1.8 10.1 53.9 5.8 62.7 6.0 12.6 21.3 0.3 10.1 0.5 11.2 1.6 18.1 2.1 0.9 10.1 3.6 4.4 2.0 3.2 0.7 26.5 79.1 7.7 24.5 3.4 1.7 2.9 0.0 5.0 7.4 9.5 8.4 1.4 8.1 6.0 2.5 4.4 1.0 10.0 3.4 7.1 15.5 9.3 11.4 4.7 10.2 10.7 7.6 3.3 6.6 1.7 2.1 6.4 5.1 1.6 1.5 3.8 4.2 1.4 2.0 1.0 2.4 1.6 0.6 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143702-14532128 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: " "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavourable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavourable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 29.7 13.7 27.6 15.8 18.9 5.8 30.3 32.6 29.7 13.7 18.5 11.3 9.2 8.3 23.1 19.3 10.4 12.2 25.2 15.1 18.9 15.0 11.7 12.6 15.8 10.9 11.0 17.7 28.9 11.5 17.2 19.6 13.7 12.3 16.3 16.5 23.3 10.5 14.0 19.8 16.0 15.6 22.7 11.6 24.2 13.7 11.3 11.5 7.4 10.0 11.9 12.3 15.6 16.9 3.8 2.7 0.3 1.9 4.3 0.6 0.4 12.2 4.4 10.6 5.0 22.7 29.8 12.1 11.3 13.5 9.1 10.5 2.8 4.8 2.8 8.5 15.4 3.7 1.7 5.3 18.9 7.8 2.5 1.5 11.8 3.5 11.8 3.7 4.2 13.9 5.6 32.2 10.3 8.0 0.3 1.9 22.0 2.3 0.0 2.6 2.6 4.0 2.8 6.4 9.4 8.9 5.5 4.8 19.5 9.6 2.5 5.0 1.5 0.5 18.6 17.6 11.2 12.7 13.3 0.0 0.6 3.6 62.5 2.4 4.1 0.3 1.5 0.0 0.1 1.9 0.3 2.0 0.0 0.0 1.4 3.8 0.0 0.0 0.0 4.3 1.4 2.7 0.6 0.4 27.6 18.9 32.6 29.7 18.9 15.0 11.0 17.7 12.3 11.5 TSSK1B "FKSG81, SPOGA4, STK22D, TSSK1" ENSG00000212122 "Testis specific serine kinase 1B" Q9BXA7 5 113432554-113435031 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "testis: 59.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.3;EFO-21: 2.1;RT4: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA027827 Enhanced "HPA027827: AB_10603138" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.6 0.1 0.2 0.0 1.0 0.0 0.0 0.0 0.2 0.0 1.3 0.2 2.1 0.0 0.4 0.2 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.5 0.1 0.0 0.1 0.3 0.0 0.4 0.0 0.5 0.2 0.2 0.3 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSSK3 "SPOGA3, STK22C" ENSG00000162526 "Testis specific serine kinase 3" Q96PN8 1 32351521-32364312 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 68.1" "Cell line enhanced" "Detected in many" "HeLa: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA037516 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA037516: " "unprognostic (5.71e-2)" "unprognostic (1.42e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-1)" "unprognostic (7.69e-2)" "unprognostic (2.02e-4)" "unprognostic (2.06e-1)" "unprognostic (1.98e-3)" "unprognostic (2.05e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (9.20e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.68e-3)" 1.1 2.0 0.8 1.7 0.8 8.2 1.1 3.9 0.8 1.3 0.9 0.8 1.4 2.5 1.8 2.9 0.8 1.3 1.0 0.9 0.8 0.0 0.9 1.3 1.4 2.4 0.8 0.8 2.0 1.2 0.0 0.8 0.8 1.0 1.0 0.0 0.8 1.4 0.8 1.7 3.4 2.9 0.8 0.8 3.4 1.2 68.1 0.8 0.8 1.3 0.8 0.8 0.9 1.1 0.6 0.1 0.1 0.7 0.3 2.3 0.1 2.3 2.3 6.0 3.6 0.0 1.2 5.4 0.7 1.1 0.0 0.0 0.5 1.2 1.2 0.9 0.0 3.7 0.0 0.0 0.0 3.5 7.2 2.7 9.8 3.7 4.4 1.1 3.4 0.1 0.9 0.0 1.3 0.0 3.1 5.8 0.0 0.6 1.4 1.5 1.5 1.2 1.9 1.7 4.4 0.0 1.9 1.8 3.8 0.8 2.8 4.1 1.9 2.7 2.9 2.1 3.4 3.0 2.4 8.5 2.8 1.8 3.7 3.9 0.5 0.0 0.1 0.0 1.1 0.7 0.0 0.0 0.2 0.0 0.1 0.6 2.3 0.9 0.1 0.3 0.5 0.0 0.0 0.1 0.8 0.8 3.9 0.8 0.8 0.0 0.8 0.8 1.0 0.8 TSSK4 "C14orf20, STK22E" ENSG00000139908 "Testis specific serine kinase 4" Q6SA08 14 24205697-24208362 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 46.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060660, HPA077103" Approved Approved "Cell Junctions" "Cell Junctions" "HPA060660: , HPA077103: " "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.52e-1)" "unprognostic (5.69e-2)" "unprognostic (2.36e-1)" "unprognostic (3.38e-5)" "unprognostic (1.06e-1)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (3.39e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-3)" "unprognostic (3.42e-1)" "unprognostic (4.30e-2)" "unprognostic (6.28e-2)" "unprognostic (8.98e-2)" "unprognostic (7.26e-2)" 0.6 0.9 0.6 1.7 0.6 3.1 0.6 1.5 1.8 0.6 0.6 0.6 0.6 1.5 0.8 0.9 1.4 0.8 1.7 0.6 0.6 0.4 0.6 0.6 0.8 2.8 0.6 0.6 0.8 0.9 0.0 0.6 0.6 0.6 0.6 0.0 0.6 1.4 0.6 1.0 4.7 1.6 0.6 0.6 1.5 0.6 46.1 0.6 0.6 1.4 0.6 0.6 1.0 0.6 2.1 1.7 2.0 1.0 1.8 2.0 0.7 1.0 4.0 3.9 1.5 0.1 0.0 4.3 1.6 0.1 0.0 0.0 2.1 3.7 3.1 0.9 0.1 3.8 0.0 0.1 0.0 1.6 3.0 3.4 4.8 3.0 0.0 1.5 3.7 0.0 0.0 0.0 0.6 0.1 1.3 2.0 0.0 3.8 3.6 1.6 0.7 3.2 2.9 1.5 2.6 0.0 5.2 2.2 2.0 2.7 2.5 0.8 1.6 1.7 1.4 2.9 1.8 3.7 1.3 4.2 4.8 4.7 1.0 2.8 0.9 0.0 1.0 2.0 2.0 1.0 0.7 2.0 1.6 1.6 0.6 2.1 1.6 1.7 2.0 1.8 0.9 1.7 0.7 0.7 0.6 0.6 1.5 0.6 0.6 0.4 0.6 0.6 0.6 0.6 TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 136.5;skeletal muscle: 713.8;tongue: 227.0" "Cell line enhanced" "Detected in many" "RH-30: 4.8" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced 25000000 "CAB022682: , HPA007042: AB_1080292, HPA030048: " "unprognostic (1.00e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (7.11e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-1)" "unprognostic (2.65e-1)" "unprognostic (3.49e-4)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" 23.7 0.3 0.2 0.3 0.3 0.9 0.3 0.2 0.4 0.2 0.2 0.0 0.0 0.2 0.2 21.3 8.3 0.2 0.3 136.5 0.2 0.2 0.2 0.2 0.4 0.4 0.2 0.0 0.3 0.4 0.2 0.3 0.3 0.0 0.7 0.2 0.0 11.6 0.2 713.8 0.3 0.2 0.2 0.3 0.3 0.2 0.4 0.0 0.0 5.6 227.0 15.8 0.3 0.2 7.0 0.3 1.9 0.3 5.0 7.3 0.1 0.7 0.3 1.9 1.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 1.8 0.3 2.4 0.6 0.0 1.7 0.0 0.0 0.0 2.3 2.0 3.7 2.6 1.0 0.0 0.3 0.8 2.4 0.0 0.0 0.0 1.4 2.1 1.2 0.4 0.4 1.6 2.5 0.4 1.8 1.3 4.8 1.3 0.0 0.6 1.0 1.7 0.4 1.3 0.0 0.7 2.4 1.6 0.0 0.0 0.9 0.4 3.5 0.4 3.5 0.1 1.1 0.9 1.9 0.3 0.7 0.5 0.2 0.2 6.9 1.2 0.9 0.2 7.0 2.7 3.5 1.3 5.0 0.2 0.3 7.3 0.1 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0