Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692112-42721298 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 21.5;ASC TERT1: 17.6;TIME: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "NK-cell: 1.4;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 13 "dendritic cells: 3.4;NK-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001141 Uncertain Mitochondria Mitochondria "HPA001141: AB_1078139" "unprognostic (2.59e-2)" "prognostic favourable (2.48e-4)" "unprognostic (2.24e-2)" "unprognostic (4.54e-3)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (4.82e-3)" "unprognostic (4.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (8.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.74e-1)" 22.7 5.9 3.5 8.2 3.7 3.8 15.3 1.4 3.8 21.2 12.0 2.3 32.6 4.8 13.0 16.9 15.0 11.7 11.0 26.8 2.3 1.3 30.0 4.4 14.0 6.4 2.9 3.0 11.8 3.4 1.4 7.7 12.6 2.9 15.4 2.1 9.9 15.4 39.8 12.5 8.7 7.0 18.6 5.3 11.4 11.3 6.7 2.4 1.3 10.7 13.0 10.1 16.1 25.6 0.1 3.4 0.0 0.0 1.4 0.0 0.0 0.6 7.3 0.0 0.0 21.5 17.6 11.0 2.9 3.1 0.6 1.1 2.3 1.2 7.1 5.1 5.1 0.7 7.0 3.4 0.1 0.0 1.4 0.1 11.5 0.2 6.5 0.0 0.5 10.3 1.0 3.0 0.5 2.5 0.0 0.0 2.7 10.0 0.0 0.0 0.9 1.8 0.0 1.6 0.7 14.5 12.5 0.1 0.0 8.9 0.2 0.0 5.7 0.8 15.4 0.0 1.4 13.1 3.8 1.5 6.7 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 3.4 0.0 0.0 3.5 3.7 1.4 3.8 2.3 1.3 2.9 3.0 2.9 2.4 AACS "ACSF1, FLJ12389, SUR-5" ENSG00000081760 "Acetoacetyl-CoA synthetase" Q86V21 12 125065379-125143333 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058815 Approved Approved Vesicles Vesicles "HPA058815: " "unprognostic (1.28e-1)" "unprognostic (9.78e-2)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-3)" "unprognostic (6.60e-6)" "unprognostic (3.03e-2)" "unprognostic (3.32e-2)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" "unprognostic (3.04e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (7.71e-2)" "unprognostic (6.80e-2)" 21.1 6.5 9.0 10.5 13.0 2.5 33.7 6.6 22.0 11.7 9.3 5.3 7.4 12.9 5.2 7.7 22.3 6.6 12.9 5.8 8.1 5.6 6.8 3.3 4.9 4.9 5.1 13.1 4.9 9.7 5.8 6.7 4.8 10.0 6.7 8.6 5.1 33.7 12.9 3.7 26.9 8.7 4.5 4.2 4.3 12.7 9.7 3.6 6.8 7.6 12.2 8.7 5.0 9.9 3.0 11.8 6.9 2.3 5.8 5.7 3.8 14.5 14.5 6.3 8.6 23.4 15.3 10.6 11.8 11.3 14.0 12.6 18.7 9.7 9.0 12.2 14.2 15.9 11.8 12.7 7.6 9.7 10.8 7.2 9.7 14.2 19.5 5.1 7.3 16.9 10.4 11.9 12.1 10.2 5.0 5.6 8.9 26.6 5.9 6.8 8.0 17.2 1.1 16.1 12.4 14.3 22.2 17.0 4.9 12.5 19.8 9.1 14.8 11.3 9.7 6.8 10.8 7.6 9.0 12.7 7.2 9.8 8.5 8.4 7.4 6.9 2.3 6.7 4.2 0.7 5.4 3.0 3.9 3.2 2.8 1.7 5.7 3.8 0.3 5.8 0.8 11.8 2.4 3.8 9.0 13.0 6.6 22.0 8.1 5.6 5.1 13.1 10.0 3.6 AADAC "CES5A1, DAC" ENSG00000114771 "Arylacetamide deacetylase" P22760 3 151814037-151828488 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 66.2;intestine: 81.7;liver: 123.1" "Cell line enhanced" "Detected in some" "A549: 11.7;ASC diff: 4.4;EFO-21: 6.3;HBEC3-KT: 5.6" "Cancer enriched" "Detected in many" 22 "liver cancer: 153.4" "Region enriched" "Detected in single" 7 "basal ganglia: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA002911 Approved "HPA002911: AB_1078074" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.11e-2)" "unprognostic (4.41e-2)" "unprognostic (9.23e-2)" "unprognostic (7.82e-2)" "unprognostic (2.15e-1)" "unprognostic (9.89e-2)" "prognostic favourable (5.58e-6)" "prognostic unfavourable (5.02e-4)" "prognostic unfavourable (2.19e-4)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" 3.9 66.2 0.1 0.1 1.6 0.0 2.1 0.1 0.1 0.1 26.1 0.5 0.4 29.6 0.1 0.3 0.3 0.2 4.3 0.2 0.1 0.0 0.1 123.1 1.7 0.1 0.1 0.1 0.1 22.7 0.0 0.1 1.7 0.2 0.3 0.0 0.1 0.3 0.1 0.2 1.7 81.7 0.1 0.1 0.1 7.3 0.3 0.1 0.1 0.2 4.8 1.3 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 4.4 0.2 0.3 0.0 0.0 0.1 0.0 1.1 0.1 0.2 6.3 0.0 0.4 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.7 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.2 0.3 0.2 0.4 2.1 0.0 2.2 0.2 1.9 0.3 0.1 0.0 0.0 0.0 2.5 0.0 2.4 1.3 0.0 0.4 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 AADAT "KAT2, KATII, KYAT2" ENSG00000109576 "Aminoadipate aminotransferase" Q8N5Z0 4 170060222-170091699 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 56.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA037502 Enhanced Approved "Vesicles,Plasma membrane" "Plasma membrane" Vesicles "HPA037502: AB_10671759" "unprognostic (1.90e-1)" "unprognostic (1.82e-2)" "prognostic favourable (5.59e-4)" "unprognostic (4.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (7.41e-2)" "unprognostic (1.03e-2)" "unprognostic (2.97e-2)" "unprognostic (3.38e-2)" "unprognostic (1.23e-2)" "unprognostic (3.55e-1)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.39e-1)" "unprognostic (7.28e-3)" "unprognostic (1.17e-2)" 3.0 3.1 9.2 2.2 9.0 0.9 4.7 0.8 10.8 8.3 4.7 10.3 2.9 1.9 9.7 5.8 2.8 5.7 3.9 2.8 7.2 6.4 6.3 56.5 4.7 1.1 8.2 8.0 4.7 4.6 7.6 8.9 2.2 6.0 13.3 5.0 6.6 1.7 5.4 3.6 1.8 2.0 7.0 7.0 2.0 3.2 7.2 9.2 0.9 7.0 1.2 1.3 5.5 4.9 0.4 0.4 0.0 0.7 0.0 0.7 0.0 2.1 5.4 16.4 0.0 3.2 12.8 5.9 5.6 2.7 3.2 3.3 5.2 0.6 0.0 0.9 6.2 1.9 7.3 2.6 2.3 0.0 6.3 0.0 6.1 8.8 2.6 0.0 2.4 5.2 1.6 2.6 3.4 3.0 0.9 0.1 12.3 5.5 2.6 0.1 12.4 4.9 0.0 5.1 0.0 2.9 9.8 13.2 15.5 4.4 1.1 5.4 0.0 1.0 2.0 8.3 8.9 9.3 8.7 0.0 0.0 0.0 8.3 0.0 9.7 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.3 0.3 0.4 0.4 0.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 9.2 9.0 0.8 10.8 7.2 6.4 8.2 8.0 6.0 9.2 AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 109.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017931, HPA020289" Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA017931: AB_1844406, HPA020289: AB_1844407" "unprognostic (2.11e-3)" "unprognostic (3.18e-2)" "unprognostic (3.67e-1)" "unprognostic (1.01e-3)" "unprognostic (5.06e-2)" "unprognostic (4.04e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.52e-1)" "prognostic unfavourable (3.19e-4)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.76e-3)" "unprognostic (1.18e-1)" 5.1 5.9 11.0 5.7 11.9 7.8 6.9 25.2 26.5 4.8 4.2 3.9 6.3 3.8 4.7 7.1 3.8 4.9 4.3 7.9 14.4 12.8 7.2 3.1 7.5 6.8 9.4 11.6 3.3 6.7 109.7 10.3 6.9 10.2 5.0 4.6 4.7 3.6 12.3 6.8 3.7 3.7 5.4 9.3 5.5 5.4 4.1 6.9 4.7 16.0 2.1 5.3 4.9 5.8 1.0 0.8 4.1 3.9 2.8 5.6 1.3 16.5 9.9 9.1 8.8 8.7 9.7 29.3 13.5 10.7 8.2 7.2 10.0 6.6 0.5 3.3 17.5 7.7 7.0 7.0 16.7 12.3 2.9 9.0 6.0 6.8 7.9 6.3 21.4 8.3 6.2 15.4 19.9 17.3 1.9 9.3 14.2 2.8 5.8 3.3 4.4 5.5 3.9 9.9 1.4 6.4 34.7 3.0 4.8 7.8 6.0 7.0 3.5 8.9 17.2 18.3 12.3 13.1 13.2 9.2 2.4 1.0 15.3 10.7 12.5 2.5 1.4 0.6 4.5 0.6 4.2 0.4 4.0 3.0 0.8 1.0 5.6 4.5 4.1 2.8 3.9 0.7 3.1 1.3 11.0 11.9 25.2 26.5 14.4 12.8 9.4 11.6 10.2 6.9 AANAT SNAT ENSG00000129673 "Aralkylamine N-acetyltransferase" Q16613 17 76453351-76470117 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Melatonin biosynthesis" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 27.7;testis: 8.2" "Cell line enhanced" "Detected in some" "A549: 4.5;SCLC-21H: 5.6;U-266/70: 4.5;U-266/84: 4.7;U-698: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA054321 Supported Cytosol "Intracellular and membrane" Cytosol "HPA054321: " "unprognostic (7.89e-2)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.83e-2)" "unprognostic (2.03e-2)" "unprognostic (1.05e-2)" "unprognostic (3.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.61e-1)" "unprognostic (9.30e-2)" "unprognostic (4.19e-1)" "unprognostic (2.81e-7)" "unprognostic (1.04e-1)" "unprognostic (6.00e-2)" "unprognostic (4.47e-2)" "unprognostic (1.34e-2)" 0.3 0.2 1.2 3.8 0.8 2.7 0.3 1.3 1.6 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.8 0.4 1.8 0.3 1.2 1.5 0.3 0.3 0.3 3.3 1.7 0.7 0.4 0.3 0.0 0.9 0.3 1.9 0.3 0.0 27.7 0.3 0.3 1.8 3.3 0.7 0.3 1.2 2.2 0.2 8.2 0.3 0.3 0.8 0.3 0.3 0.9 0.3 1.3 1.3 2.2 0.1 1.8 0.2 0.0 0.9 4.5 0.7 0.5 0.0 0.1 0.5 0.0 0.4 0.3 0.1 0.1 3.2 3.7 0.5 0.0 1.1 0.0 0.0 0.3 0.0 1.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.9 0.4 0.5 0.1 0.1 1.2 0.4 0.2 0.2 1.9 0.0 0.1 5.6 0.4 0.1 0.2 1.5 2.8 0.7 0.0 0.0 1.8 0.2 0.1 4.5 4.7 6.6 1.2 0.4 0.8 2.0 0.1 2.2 0.2 0.0 0.0 0.6 0.1 0.0 0.0 1.3 0.0 0.2 0.6 1.8 0.0 1.3 0.1 0.0 1.2 0.8 1.3 0.9 1.2 1.5 1.7 0.7 1.9 0.3 AARS "AlaRS, CMT2N" ENSG00000090861 "Alanyl-tRNA synthetase" P49588 16 70252295-70289543 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease mutation, Epilepsy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034261, HPA040870, HPA044223" Supported Enhanced Cytosol 700000 Cytosol "CAB034261: AB_1562673, HPA040870: AB_10794995, HPA044223: AB_2678862" "unprognostic (1.98e-2)" "unprognostic (6.87e-2)" "unprognostic (8.02e-2)" "unprognostic (5.72e-2)" "unprognostic (3.58e-1)" "unprognostic (2.50e-2)" "unprognostic (7.99e-2)" "unprognostic (2.36e-1)" "unprognostic (1.99e-1)" "unprognostic (1.76e-1)" "unprognostic (8.33e-2)" "unprognostic (2.92e-1)" "unprognostic (3.42e-2)" "unprognostic (3.75e-2)" "unprognostic (2.05e-3)" "unprognostic (8.22e-2)" "unprognostic (3.83e-3)" 22.8 25.3 28.0 19.6 34.8 5.9 22.6 36.4 54.0 22.3 18.4 30.6 21.4 16.8 22.0 33.9 14.5 20.4 14.1 20.9 29.5 31.7 25.5 36.4 19.5 17.9 40.3 40.5 18.7 45.4 61.2 23.1 21.0 37.5 23.2 17.5 17.3 30.1 30.0 25.2 14.1 14.4 28.4 33.2 16.7 21.1 12.2 32.7 10.3 42.1 10.6 20.9 17.7 26.9 13.4 11.6 3.9 13.3 21.3 13.4 11.6 22.9 38.7 10.7 39.6 25.0 22.7 25.8 18.2 25.3 23.0 29.1 31.7 31.0 26.1 24.5 18.3 26.9 30.9 24.8 32.4 11.8 11.1 25.7 16.4 28.1 66.2 15.4 15.4 26.8 37.5 44.2 99.0 22.8 32.7 34.5 17.2 52.0 16.5 18.1 20.0 22.3 31.6 6.7 57.0 15.7 11.8 13.3 11.4 50.6 11.9 44.8 37.3 33.9 15.0 17.0 16.5 16.8 15.1 48.7 31.9 48.1 29.1 24.1 33.2 3.9 8.6 3.9 12.6 12.7 12.8 13.4 10.9 12.1 11.6 11.4 13.1 13.4 1.3 21.3 13.3 7.9 8.4 11.6 28.0 34.8 36.4 54.0 29.5 31.7 40.3 40.5 37.5 32.7 AARS2 "AARSL, bA444E17.1, KIAA1270" ENSG00000124608 "Alanyl-tRNA synthetase 2, mitochondrial" Q5JTZ9 6 44299654-44313326 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Cancer-related genes, Cardiomyopathy, Disease mutation, Premature ovarian failure, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035636, HPA061396" Approved Enhanced Mitochondria Mitochondria "HPA035636: AB_10670837, HPA061396: " "unprognostic (1.56e-1)" "unprognostic (3.24e-2)" "unprognostic (2.58e-2)" "unprognostic (2.04e-3)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (8.83e-3)" "unprognostic (5.12e-2)" "unprognostic (3.64e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-2)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" 8.6 10.7 15.9 16.2 11.8 11.4 9.9 23.5 19.8 11.4 14.5 11.4 13.0 15.3 14.1 10.4 17.2 13.4 15.9 10.4 13.2 8.9 10.3 12.6 10.9 13.4 12.4 14.3 17.1 13.8 16.2 14.2 10.1 11.1 13.2 9.8 11.2 14.4 14.6 10.2 16.8 18.3 12.1 8.8 14.1 12.3 12.9 14.1 14.7 12.3 10.4 13.4 10.2 13.9 7.1 3.2 3.7 3.4 3.7 5.5 2.8 10.4 7.9 10.3 19.0 6.1 5.7 13.7 8.7 4.5 9.2 8.9 8.5 5.7 11.5 13.9 3.7 7.9 11.4 12.4 3.6 8.1 18.3 13.4 7.7 10.0 4.0 12.4 11.9 4.8 7.9 7.4 7.9 7.8 15.8 11.3 4.9 11.7 10.4 10.7 7.7 7.7 12.4 6.3 7.9 4.8 9.5 24.6 8.9 7.5 8.4 11.6 7.8 16.2 6.6 10.0 10.0 6.1 10.8 6.7 6.2 11.9 5.6 11.0 17.1 3.7 2.4 0.0 3.4 3.3 5.5 3.6 4.8 4.4 2.6 7.1 4.7 4.3 0.7 3.7 3.4 3.2 3.0 2.8 15.9 11.8 23.5 19.8 13.2 8.9 12.4 14.3 11.1 14.1 AASS "LKRSDH, LORSDH" ENSG00000008311 "Aminoadipate-semialdehyde synthase" Q9UDR5 7 122075647-122144280 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 26.1;NTERA-2: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 3.5" "Group enriched" "Detected in many" 4 "B-cells: 1.0;granulocytes: 3.5;T-cells: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020637, HPA020728, HPA020734" Enhanced Enhanced Vesicles,Mitochondria 17000 Mitochondria Vesicles "HPA020637: AB_1844415, HPA020728: AB_1844416, HPA020734: AB_1844417" "unprognostic (4.84e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-4)" "unprognostic (6.08e-2)" "unprognostic (1.49e-2)" "unprognostic (8.00e-2)" "prognostic favourable (9.81e-4)" "unprognostic (4.48e-3)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (1.99e-1)" "unprognostic (7.76e-3)" "unprognostic (8.56e-3)" "unprognostic (1.55e-1)" "unprognostic (6.50e-2)" "unprognostic (2.67e-1)" 13.9 9.5 7.4 4.8 11.8 1.6 11.2 2.7 9.8 16.0 8.1 12.5 8.2 2.2 16.8 11.6 6.4 14.9 6.7 12.6 8.8 3.7 14.4 35.8 9.1 3.3 15.2 5.0 36.7 10.7 14.9 10.4 7.1 9.9 9.2 3.8 9.2 5.4 10.4 11.3 4.4 5.5 9.3 12.1 5.2 9.0 5.1 13.2 0.8 7.8 8.3 3.1 11.0 9.0 1.0 0.4 3.5 0.1 0.3 1.2 0.1 0.1 0.0 16.2 26.1 13.5 8.7 6.3 4.4 4.7 4.6 6.7 7.4 0.2 0.0 0.3 3.1 2.8 18.6 8.4 6.3 0.0 6.8 5.6 3.6 4.8 11.1 0.0 1.8 7.6 0.2 5.5 5.8 11.0 1.5 10.3 3.1 0.0 0.5 0.0 25.5 1.0 8.4 8.6 0.3 2.1 1.8 1.6 0.5 1.4 0.0 2.7 0.4 0.0 5.0 9.0 2.7 4.1 4.2 2.2 1.6 0.0 3.3 0.5 3.4 3.5 0.1 0.0 0.7 0.0 0.1 0.5 0.8 0.0 0.4 1.0 1.2 0.5 0.0 0.3 0.0 0.0 0.7 0.1 7.4 11.8 2.7 7.3 8.8 3.7 15.2 5.0 9.9 13.2 AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81117295-81166077 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.3;intestine: 28.7" "Group enriched" "Detected in some" 6 "CACO-2: 29.6;SH-SY5Y: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21 "neutrophil: 3.6" "Lineage enriched" "Detected in single" 21 "granulocytes: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Enhanced Uncertain Mitochondria Mitochondria "HPA009073: AB_1078076" "unprognostic (3.47e-3)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-4)" "unprognostic (1.96e-1)" "unprognostic (1.94e-1)" "unprognostic (7.29e-2)" "unprognostic (9.85e-2)" "unprognostic (6.09e-2)" "unprognostic (4.27e-2)" "unprognostic (2.88e-3)" "unprognostic (2.48e-1)" "unprognostic (4.28e-6)" "unprognostic (1.58e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-2)" 2.8 4.7 14.3 3.2 16.6 3.7 0.9 19.0 29.0 1.2 3.3 16.5 0.0 28.7 1.0 1.1 1.7 1.2 2.7 2.3 23.6 13.9 1.2 1.2 9.7 1.5 20.1 13.6 1.0 17.9 3.6 6.4 2.6 11.0 2.4 1.1 4.1 5.6 3.6 1.1 1.9 20.3 1.3 35.3 5.9 4.5 1.3 9.8 0.0 1.3 0.0 1.0 1.3 1.1 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.2 0.3 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 29.6 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 1.6 1.1 1.4 1.8 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 3.1 0.0 0.1 0.5 0.1 1.3 2.4 0.2 0.0 0.0 2.8 10.2 0.2 0.0 1.4 0.3 0.8 1.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 14.3 16.6 19.0 22.3 23.6 13.9 20.1 13.6 11.0 9.8 ABAT GABAT ENSG00000183044 "4-aminobutyrate aminotransferase" P80404 16 8674565-8784575 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Neurotransmitter degradation" "Aminotransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 53.3;liver: 136.5;pancreas: 54.2" "Cell line enhanced" "Detected in many" "Hep G2: 44.3;MCF7: 28.5;RH-30: 25.1;T-47d: 15.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041528, HPA041690" Enhanced Supported Supported Mitochondria 1500000 Mitochondria "HPA041528: AB_10795690, HPA041690: AB_10794674" "unprognostic (1.77e-2)" "unprognostic (3.27e-1)" "unprognostic (1.00e-1)" "unprognostic (2.71e-1)" "unprognostic (2.90e-1)" "unprognostic (2.05e-1)" "prognostic favourable (5.36e-5)" "prognostic favourable (5.93e-4)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "prognostic favourable (5.44e-8)" "unprognostic (2.10e-1)" "unprognostic (2.48e-2)" "unprognostic (3.80e-1)" "unprognostic (1.50e-2)" 2.1 12.6 26.1 2.7 39.3 1.7 3.2 19.9 43.3 2.2 5.2 10.9 0.1 17.5 2.1 5.0 3.0 2.8 2.7 6.2 20.4 30.9 53.3 136.5 2.8 2.8 24.5 26.1 5.3 54.2 4.0 22.1 2.3 14.3 9.9 4.2 2.6 2.6 2.5 1.4 2.1 8.4 2.1 14.1 2.5 3.9 6.3 11.8 1.0 12.7 0.4 3.3 6.4 1.1 2.2 1.9 8.8 5.8 1.6 2.5 1.8 0.2 0.0 11.8 6.7 1.9 0.6 0.5 1.4 0.8 0.7 0.2 4.4 0.3 1.4 0.5 0.8 3.0 0.7 2.8 0.9 0.8 0.6 1.9 0.0 44.3 3.1 0.4 3.0 2.5 1.2 1.2 0.5 0.2 0.3 1.0 0.2 28.5 0.7 0.2 1.0 0.1 3.4 25.1 0.6 0.4 7.0 1.9 5.7 0.6 0.4 0.0 15.6 1.2 0.2 0.2 2.0 0.9 0.0 1.1 0.1 0.3 0.3 2.0 1.4 1.1 3.1 4.1 2.5 3.6 1.1 0.8 1.7 1.7 1.9 2.2 1.1 1.8 8.8 1.6 5.8 0.3 1.6 1.8 26.1 39.3 19.9 35.1 20.4 30.9 24.5 26.1 14.3 11.8 ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503633-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 57.8;intestine: 49.6" "Cell line enhanced" "Detected in some" "CACO-2: 29.4;HEK 293: 9.0;HEL: 16.3;Hep G2: 8.1;RPTEC TERT1: 11.3;SH-SY5Y: 36.0" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "MAIT T-cell: 19.2" "Group enriched" "Detected in many" 8 "NK-cells: 11.4;T-cells: 19.2" "CAB001716, HPA002199" Enhanced Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Nucleoplasm, Focal adhesion sites, Cytosol" "CAB001716: , HPA002199: AB_1844428" "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favourable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favourable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" 2.6 57.8 9.4 3.2 11.5 1.2 3.4 5.1 10.5 5.5 22.7 3.8 2.0 14.4 9.4 3.5 2.0 3.2 9.0 1.8 9.2 6.6 19.1 15.6 3.8 2.2 9.4 5.7 2.2 1.5 1.7 1.3 3.1 11.1 2.7 10.7 7.6 1.5 2.1 1.1 1.3 49.6 5.7 9.0 2.4 1.7 1.3 8.6 0.1 2.4 1.4 2.2 2.6 5.9 1.9 0.0 0.1 0.0 11.4 19.2 1.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 29.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 9.0 16.3 1.9 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 11.3 0.0 0.4 36.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.4 3.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 7.8 0.0 19.2 0.4 2.0 4.7 0.0 1.9 1.2 4.8 0.1 11.4 0.0 0.0 0.0 1.5 9.4 11.5 5.1 10.5 9.2 6.6 9.4 5.7 11.1 8.6 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401697-87480435 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease mutation, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 93.2" "Group enriched" "Detected in some" 5 "SH-SY5Y: 11.7;WM-115: 22.3" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 6 "memory B-cell: 4.9;naive B-cell: 11.4" "Lineage enriched" "Detected in many" 8 "B-cells: 11.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: , HPA053288: " "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.5 4.1 0.2 4.3 0.2 0.2 0.3 0.1 1.1 0.2 0.6 0.4 0.0 0.0 0.1 0.2 0.6 0.1 0.3 4.0 0.3 0.2 0.4 93.2 0.1 4.1 0.3 0.2 0.3 0.1 0.0 0.5 0.0 0.3 0.3 0.4 0.8 0.4 0.1 2.9 0.6 1.2 1.6 0.5 5.2 0.2 0.5 0.4 0.1 0.4 4.2 3.2 0.6 0.5 11.4 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.3 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 11.7 0.0 0.5 2.2 0.2 0.5 0.0 0.2 1.6 0.1 0.0 0.0 0.0 2.7 0.2 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.1 4.9 0.0 0.1 1.4 11.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.2 0.1 1.1 0.3 0.2 0.3 0.2 0.3 0.4 ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10" Q9NUJ1 3 111979010-111993363 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria "Intracellular and membrane" 85000 Mitochondria "HPA036991: , HPA036992: AB_10672345, HPA066081: " "unprognostic (1.65e-1)" "prognostic favourable (7.57e-4)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (1.14e-1)" "unprognostic (8.50e-2)" "unprognostic (1.69e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-2)" "prognostic favourable (4.72e-9)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (4.18e-3)" "unprognostic (2.76e-2)" 8.5 18.3 17.5 8.1 27.5 7.6 12.4 23.2 23.2 9.9 11.3 13.7 8.6 9.4 9.4 42.4 7.0 12.5 8.4 19.8 18.6 19.6 39.1 26.6 9.7 14.0 17.0 21.6 16.8 12.1 8.8 26.1 8.8 19.1 17.1 12.3 12.6 19.8 12.0 10.4 8.2 8.6 8.9 14.8 12.4 11.6 12.6 15.1 16.6 25.3 6.7 12.6 8.7 7.9 18.3 19.7 17.7 14.8 7.8 12.7 10.8 18.6 16.2 17.9 5.8 10.3 13.9 9.7 19.7 10.4 16.2 15.7 16.6 10.8 16.9 11.1 8.2 10.4 7.9 11.0 22.4 5.7 10.0 13.9 8.0 14.4 8.2 27.9 15.0 8.5 8.2 8.3 21.1 17.4 6.3 7.2 17.8 6.2 26.2 13.0 11.6 25.7 23.8 11.4 7.8 16.9 8.1 12.1 8.8 15.8 11.5 18.4 12.9 10.2 9.7 9.7 12.5 7.0 10.3 11.6 4.1 28.8 9.8 15.3 10.3 17.7 11.8 17.5 7.4 14.8 12.7 18.3 9.3 8.4 19.7 15.9 12.0 10.5 1.8 7.8 11.6 12.5 8.8 10.8 17.5 27.5 23.2 23.2 18.6 19.6 17.0 21.6 19.1 15.1 ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12" Q8N2K0 20 25294743-25390983 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease mutation, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 71.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain "HPA026866: AB_1844446" "prognostic unfavourable (3.81e-5)" "prognostic favourable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavourable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" 11.3 13.4 27.4 10.0 32.1 9.8 10.4 22.3 39.8 11.1 15.6 30.8 14.1 20.7 9.1 58.9 20.4 11.3 14.0 12.2 41.5 25.9 18.9 13.1 14.0 10.3 31.5 21.0 13.8 65.6 16.0 14.4 25.6 26.9 15.6 15.2 11.5 13.8 17.4 4.0 16.2 21.1 9.9 43.3 7.8 22.1 7.6 19.0 10.2 36.8 7.9 16.0 15.7 10.9 3.9 14.6 12.6 14.2 11.1 11.5 6.0 14.8 34.1 8.8 11.0 18.1 10.8 21.7 21.4 17.9 16.8 19.4 19.9 22.8 4.7 12.1 16.8 24.2 11.1 12.7 14.4 4.8 8.9 7.5 9.3 27.6 14.4 7.2 16.1 13.4 8.3 20.7 9.8 7.7 5.5 71.3 15.9 30.7 11.0 7.7 6.7 21.6 8.4 22.6 44.5 11.3 30.9 11.3 9.4 18.0 44.5 31.7 15.1 12.4 9.6 21.3 14.4 12.9 12.3 8.4 7.7 7.5 14.8 8.6 13.7 9.8 14.2 12.6 8.0 12.2 6.4 3.1 8.8 11.5 14.6 3.9 7.5 7.4 1.8 11.1 13.1 13.1 7.9 6.0 27.4 32.1 22.3 39.8 41.5 25.9 31.5 21.0 26.9 19.0 ABHD17A "C19orf27, FAM108A1, MGC5244" ENSG00000129968 "Abhydrolase domain containing 17A" Q96GS6 19 1876810-1885547 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043270, HPA047226" Uncertain Approved Vesicles Vesicles "HPA043270: AB_2678401, HPA047226: AB_2679991" "unprognostic (3.77e-2)" "unprognostic (1.85e-1)" "unprognostic (3.57e-2)" "prognostic favourable (1.73e-4)" "unprognostic (3.70e-2)" "prognostic favourable (6.46e-4)" "unprognostic (1.69e-2)" "unprognostic (1.92e-2)" "unprognostic (5.09e-1)" "unprognostic (1.44e-1)" "prognostic favourable (1.76e-5)" "unprognostic (1.29e-2)" "unprognostic (1.85e-3)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (3.17e-1)" "unprognostic (1.60e-2)" 28.1 11.9 26.6 8.9 23.9 10.0 6.8 16.4 29.4 9.0 14.1 15.3 10.3 16.5 8.8 7.0 9.9 7.1 11.7 12.9 30.9 14.4 11.9 8.2 13.0 9.1 19.0 16.7 9.4 16.6 3.8 7.7 13.4 13.2 13.9 2.1 8.4 21.0 11.2 47.4 20.7 15.8 5.2 25.5 25.7 23.3 12.1 7.9 10.9 11.4 9.6 7.1 6.3 7.3 4.5 1.5 5.9 1.5 4.7 8.5 1.0 16.6 5.7 1.7 6.5 3.0 3.8 13.1 11.2 3.4 3.1 3.0 2.7 2.9 8.2 4.6 2.4 10.4 1.1 4.3 0.1 18.8 24.8 6.0 2.2 7.4 4.4 6.0 20.6 4.0 3.5 1.7 1.2 6.5 10.3 9.2 2.2 9.4 10.8 11.9 12.7 13.0 12.7 5.8 12.2 2.2 3.4 7.8 17.8 5.9 6.3 10.7 6.6 11.0 12.3 3.7 8.7 15.0 10.9 37.1 22.2 6.8 8.4 8.1 6.1 2.5 1.5 5.9 8.5 0.9 6.2 4.5 3.9 5.5 1.5 2.4 4.1 4.4 1.7 4.7 1.0 1.5 3.5 1.0 26.6 23.9 16.4 29.4 30.9 14.4 19.0 16.7 13.2 7.9 ABHD17B "C9orf77, CGI-67, FAM108B1" ENSG00000107362 "Abhydrolase domain containing 17B" Q5VST6 9 71862452-71910931 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 46.2" "Cell line enhanced" "Detected in many" "REH: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047862 Uncertain "HPA047862: AB_10959595" "unprognostic (7.47e-2)" "unprognostic (4.41e-2)" "unprognostic (4.03e-3)" "unprognostic (5.59e-2)" "unprognostic (5.57e-2)" "unprognostic (8.53e-3)" "unprognostic (9.44e-2)" "unprognostic (6.84e-2)" "unprognostic (5.46e-2)" "unprognostic (3.44e-2)" "unprognostic (3.49e-2)" "unprognostic (1.74e-1)" "prognostic favourable (2.59e-4)" "unprognostic (4.33e-2)" "unprognostic (2.12e-1)" "unprognostic (3.06e-3)" "unprognostic (1.34e-2)" 7.7 6.6 16.5 6.9 25.0 18.0 8.2 14.4 21.6 9.0 12.0 43.3 2.3 18.1 9.5 4.6 13.5 9.6 9.1 5.8 23.6 13.8 13.4 13.6 7.5 10.8 44.0 13.6 7.6 6.4 12.7 5.8 7.8 24.3 11.0 11.2 9.0 9.4 5.1 13.6 11.2 14.9 9.4 30.4 8.9 8.9 11.1 38.2 46.2 8.8 3.6 10.7 11.8 8.8 7.2 5.7 8.1 3.8 6.6 4.9 1.7 6.4 6.2 14.2 8.2 7.4 4.6 12.5 7.1 7.8 6.2 5.3 1.8 4.0 15.6 6.6 4.8 12.8 13.8 4.7 7.2 8.1 8.2 9.1 10.5 6.0 5.2 10.7 14.9 5.7 6.6 5.5 5.0 8.0 7.4 7.1 5.2 2.9 27.8 8.6 21.5 8.8 37.3 10.9 0.1 7.1 13.0 9.5 11.0 7.5 8.1 6.1 2.6 7.8 6.4 6.0 7.8 11.1 5.7 7.0 8.2 12.3 4.7 7.7 3.0 8.1 3.8 4.1 3.1 1.4 3.0 4.2 3.8 4.3 4.8 7.2 3.2 4.5 2.9 6.6 1.3 5.7 4.9 1.7 16.5 25.0 14.4 20.8 23.6 13.8 44.0 13.6 24.3 38.2 ABHD17C FAM108C1 ENSG00000136379 "Abhydrolase domain containing 17C" Q6PCB6 15 80679684-80755621 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 34.6;SK-MEL-30: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048890 Uncertain "HPA048890: " "unprognostic (3.60e-1)" "unprognostic (5.07e-2)" "unprognostic (1.58e-1)" "unprognostic (2.19e-2)" "unprognostic (7.51e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (2.59e-2)" "unprognostic (5.08e-3)" "unprognostic (2.87e-1)" "unprognostic (1.23e-3)" "unprognostic (5.75e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" "unprognostic (1.89e-3)" 2.1 3.8 14.6 16.8 16.0 3.7 8.0 6.6 13.0 13.8 42.0 5.4 4.6 15.5 4.5 1.8 31.7 7.7 12.2 3.1 10.7 8.5 10.4 5.4 27.2 11.6 8.2 8.2 2.0 8.3 5.1 6.0 19.7 5.7 12.6 38.1 3.9 16.2 6.0 1.6 12.6 25.9 6.8 6.2 5.7 23.5 3.6 5.6 2.7 7.8 13.9 23.2 13.8 13.0 1.2 1.1 0.0 0.5 0.0 2.8 0.3 8.7 8.3 5.4 6.8 2.0 4.1 9.3 8.4 31.8 7.2 7.0 6.9 19.6 2.9 3.4 8.9 18.0 15.1 7.7 6.5 20.5 8.5 0.0 6.4 7.3 3.5 2.6 4.2 8.8 9.4 5.2 2.5 7.7 0.0 3.7 4.1 24.3 0.2 0.2 8.0 3.1 5.7 4.6 8.1 5.8 34.6 4.8 2.0 6.7 11.6 38.3 5.7 4.5 2.6 4.4 3.6 4.8 7.4 0.3 0.1 2.8 2.9 24.0 4.9 0.0 0.1 0.0 2.7 0.3 2.0 1.2 2.1 2.8 0.4 0.1 0.3 0.6 0.0 0.0 0.5 1.1 0.1 0.3 14.6 16.0 6.6 13.0 10.7 8.5 8.2 8.2 5.7 5.6 ABHD2 LABH2 ENSG00000140526 "Abhydrolase domain containing 2" P08910 15 89087459-89202360 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HEL: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 29.0;neutrophil: 22.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005999 Approved Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA005999: AB_1078080" "unprognostic (6.60e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.00e-2)" "unprognostic (2.16e-1)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (1.67e-1)" "unprognostic (3.34e-1)" "unprognostic (3.67e-3)" "unprognostic (3.41e-3)" "unprognostic (1.80e-1)" "prognostic favourable (2.18e-7)" "unprognostic (4.17e-1)" "unprognostic (3.07e-2)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" 13.2 24.8 14.8 9.5 19.3 15.6 11.7 25.2 23.4 10.7 16.1 12.0 6.5 23.4 18.2 34.7 9.0 12.1 32.2 24.5 12.2 11.3 11.8 76.4 22.2 11.2 11.1 14.8 13.1 28.3 11.2 18.1 5.6 19.8 22.9 9.6 22.6 11.8 10.0 19.3 7.5 18.5 11.4 8.3 14.2 35.8 42.9 7.6 7.7 8.6 8.1 12.1 13.5 10.4 1.1 3.0 29.0 7.0 4.7 3.5 2.5 8.0 15.5 3.8 4.1 7.5 10.2 2.1 5.4 16.2 5.2 4.9 3.9 14.0 2.3 6.3 6.7 10.7 8.4 6.6 7.3 12.0 3.8 83.5 3.6 2.9 3.9 5.7 19.7 5.2 4.7 18.5 11.9 6.3 7.4 7.2 14.2 3.3 3.5 1.4 1.7 4.6 5.1 8.0 17.4 6.9 12.6 6.6 9.9 10.3 4.9 8.6 5.4 4.5 9.6 18.3 6.2 6.6 13.6 5.9 11.7 2.7 14.9 5.3 14.2 3.1 5.6 29.0 1.6 4.8 0.9 1.1 1.5 1.5 3.0 1.1 1.4 1.5 22.7 4.7 7.0 2.4 3.5 2.5 14.8 19.3 25.2 23.4 12.2 11.3 11.1 14.8 19.8 7.6 ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3" Q8WU67 18 21650897-21704805 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 54.1;RPMI-8226: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA010729: AB_1844449" "unprognostic (1.46e-1)" "unprognostic (4.61e-2)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (8.46e-2)" "unprognostic (3.14e-3)" "unprognostic (3.54e-3)" "unprognostic (1.52e-1)" "prognostic unfavourable (8.52e-4)" "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.58e-2)" 9.2 5.4 12.0 14.2 10.7 8.6 20.7 19.5 11.1 6.4 34.2 4.8 5.1 23.8 6.0 5.4 12.7 7.8 13.5 7.1 8.8 8.5 8.7 21.7 12.8 21.3 11.5 5.0 9.4 8.8 10.7 11.8 10.8 16.6 6.9 37.1 14.7 10.3 4.1 10.1 3.8 45.3 5.5 12.3 17.9 19.0 4.4 10.8 20.9 12.9 6.7 13.7 9.2 25.5 7.1 6.1 33.0 23.3 7.1 17.6 9.1 7.4 5.4 5.3 3.4 3.4 2.2 0.0 4.9 2.0 3.5 4.8 5.6 7.7 21.4 9.0 1.6 24.8 8.6 4.0 4.9 13.4 6.0 2.3 9.1 9.6 5.2 10.1 7.8 2.0 4.8 5.2 2.4 2.3 5.9 12.8 3.1 3.0 9.7 11.3 2.6 12.8 54.1 4.0 60.2 9.7 7.2 4.5 2.0 11.2 10.0 2.8 3.1 17.9 1.8 3.4 4.9 6.0 7.5 14.4 9.3 22.1 4.4 13.3 7.8 29.1 10.2 11.4 11.1 17.9 8.5 7.1 10.0 10.6 6.1 5.1 8.2 10.3 33.0 7.1 23.3 4.2 17.6 9.1 12.0 10.7 19.5 11.1 8.8 8.5 11.5 5.0 16.6 10.8 ABHD4 FLJ12816 ENSG00000100439 "Abhydrolase domain containing 4" Q8TB40 14 22598237-22613215 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000600 Uncertain Approved Nucleoplasm Nucleoplasm "HPA000600: AB_1078081" "unprognostic (5.04e-2)" "unprognostic (5.15e-2)" "unprognostic (2.68e-3)" "unprognostic (8.17e-2)" "unprognostic (1.17e-1)" "unprognostic (5.24e-2)" "unprognostic (1.19e-3)" "unprognostic (3.69e-2)" "unprognostic (1.28e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (3.73e-1)" "unprognostic (1.56e-2)" "unprognostic (5.18e-2)" "unprognostic (1.37e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" 17.2 24.9 12.8 6.4 14.5 10.0 20.5 12.3 13.9 19.4 14.7 21.4 37.5 13.4 26.0 26.2 28.6 14.4 22.4 16.4 14.1 10.4 23.9 17.0 13.6 8.7 18.9 12.9 15.4 11.4 14.8 12.2 15.9 15.5 19.3 12.8 22.2 13.9 35.5 17.9 14.2 26.3 22.8 18.5 11.9 18.5 45.0 16.4 5.1 25.1 11.1 14.7 23.2 20.7 3.8 2.8 18.6 4.2 4.4 6.0 3.4 8.0 13.5 5.5 5.0 44.8 16.3 5.3 3.6 18.5 9.1 17.0 8.1 12.9 0.7 9.6 15.8 15.7 3.5 9.4 7.5 5.9 1.2 3.0 9.4 26.8 20.5 0.4 10.9 20.6 7.4 11.9 10.2 9.3 2.2 14.7 8.3 4.4 0.2 0.4 6.7 9.8 2.2 4.9 3.3 10.6 8.6 0.3 1.1 24.3 8.7 9.3 3.4 0.9 6.6 4.0 5.5 6.4 1.4 15.9 8.2 0.2 3.0 0.6 3.1 18.6 4.2 6.6 6.0 3.2 5.0 3.8 3.9 3.9 2.8 2.4 1.3 2.6 17.4 4.4 2.9 0.4 2.3 3.4 12.8 14.5 12.3 13.0 14.1 10.4 18.9 12.9 15.5 16.4 ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 70.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 26.1;classical monocyte: 7.6;neutrophil: 21.0" "Group enriched" "Detected in many" 5 "granulocytes: 26.1;monocytes: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Approved Vesicles Vesicles "CAB020685: , HPA035851: AB_10671942, HPA035852: AB_10672073" "unprognostic (2.58e-1)" "unprognostic (2.73e-1)" "prognostic favourable (8.89e-4)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (6.13e-2)" "unprognostic (2.40e-2)" "unprognostic (5.33e-2)" "unprognostic (3.50e-3)" "unprognostic (2.56e-2)" "unprognostic (4.13e-3)" "prognostic favourable (9.17e-5)" "unprognostic (2.48e-1)" "unprognostic (8.87e-2)" "unprognostic (4.18e-2)" "unprognostic (4.18e-2)" 26.5 10.5 5.2 7.4 12.2 32.2 70.3 8.5 10.3 7.6 10.2 10.5 5.9 7.4 4.6 4.0 22.7 3.7 10.4 9.8 7.4 4.5 10.1 18.4 14.1 8.7 18.5 4.6 4.2 12.8 9.1 8.6 20.2 14.9 5.8 6.7 4.4 21.1 7.4 10.4 24.8 15.1 8.1 19.0 7.0 8.9 8.1 12.5 3.3 13.2 9.9 6.7 11.2 16.0 1.7 3.6 26.1 7.6 0.9 2.4 2.5 8.3 2.9 3.5 3.7 14.9 5.7 7.3 34.2 13.6 9.4 7.1 4.6 2.9 7.0 4.7 10.7 2.8 5.5 8.3 9.6 25.3 5.4 17.8 11.4 3.1 7.4 4.0 5.8 6.3 28.9 15.8 13.5 15.7 10.6 5.3 20.9 4.5 2.9 2.8 9.5 9.6 1.2 10.2 4.0 12.2 16.7 4.4 5.9 15.0 8.1 3.5 8.7 3.5 8.7 8.3 6.6 15.4 14.8 4.8 13.3 3.3 8.9 7.4 6.4 26.1 7.6 4.4 1.2 3.7 1.0 1.7 0.9 1.4 3.6 1.2 0.8 1.3 21.0 0.9 2.7 0.9 2.4 2.5 5.2 12.2 8.5 10.3 7.4 4.5 18.5 4.6 14.9 12.5 ABHD6 ENSG00000163686 "Abhydrolase domain containing 6" Q9BV23 3 58237506-58295693 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 43.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017283, HPA073225" Uncertain Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA017283: AB_1844452, HPA073225: " "unprognostic (4.20e-2)" "unprognostic (7.92e-2)" "prognostic favourable (1.13e-4)" "unprognostic (2.35e-2)" "unprognostic (1.16e-2)" "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (1.15e-2)" "unprognostic (9.54e-2)" "unprognostic (1.11e-3)" "unprognostic (1.34e-2)" "unprognostic (1.94e-1)" "prognostic favourable (1.11e-11)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (2.72e-1)" "unprognostic (6.31e-2)" 8.3 10.0 11.6 4.6 14.0 1.0 5.8 17.7 22.5 3.7 8.1 30.0 10.3 26.3 4.7 10.8 4.8 6.9 4.4 4.1 19.0 9.2 24.3 43.4 6.3 5.2 18.6 12.2 4.1 2.4 4.8 15.2 4.8 19.0 4.4 8.1 10.5 3.0 12.9 3.1 17.2 33.5 6.8 24.0 22.8 9.0 3.1 14.3 2.0 6.6 2.1 5.4 4.6 4.1 3.9 7.0 2.1 9.3 0.7 2.6 1.1 2.1 8.0 1.2 5.3 15.1 2.7 14.0 5.6 5.1 5.9 8.1 4.2 2.9 4.0 0.5 3.1 6.3 5.4 2.5 5.3 6.9 2.7 3.4 5.4 5.8 5.1 1.0 18.4 2.6 11.6 5.4 2.7 3.3 4.1 9.4 4.8 1.6 7.0 0.4 3.9 17.7 2.6 2.4 9.1 9.1 2.9 7.0 2.8 6.2 3.4 11.6 2.3 2.8 3.5 4.3 4.7 10.6 6.6 2.8 8.0 0.2 11.0 10.3 5.8 0.0 2.8 2.1 2.1 9.3 2.0 3.9 1.2 2.6 4.6 3.0 1.2 1.5 0.0 0.7 6.2 7.0 1.4 1.1 11.6 14.0 17.7 22.5 19.0 9.2 18.6 12.2 19.0 14.3 ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713946-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 20.1 11.6 12.4 15.0 18.1 10.7 22.0 6.7 16.0 28.9 34.3 29.1 12.1 11.9 26.6 16.9 21.4 20.8 30.9 14.2 10.3 8.4 9.9 6.7 13.8 8.7 24.1 9.4 24.2 12.2 27.7 14.5 13.6 17.1 27.3 15.8 19.4 14.6 18.0 10.8 14.2 17.0 66.6 14.3 10.8 21.9 9.8 21.2 5.8 19.5 11.4 9.1 35.8 31.9 3.1 3.1 1.1 5.0 2.4 2.6 1.6 7.0 15.7 16.9 20.4 24.8 30.3 6.2 12.4 19.5 14.6 12.4 12.3 9.2 11.6 7.2 16.5 13.7 8.5 11.5 10.8 7.3 5.3 7.6 26.9 10.5 16.9 11.7 10.7 22.1 12.7 26.1 16.2 20.2 42.6 9.3 17.8 13.4 14.8 9.6 18.7 11.6 17.2 21.9 12.6 14.7 8.3 15.8 19.7 20.8 8.1 10.0 15.9 10.8 23.1 56.0 14.5 21.4 19.5 2.8 6.6 15.6 23.1 9.7 17.7 0.2 2.1 1.1 2.0 1.2 2.6 3.1 2.0 1.9 2.0 1.4 1.9 1.7 0.2 2.4 5.0 3.1 0.9 1.6 12.4 18.1 6.7 16.0 10.3 8.4 24.1 9.4 17.1 21.2 ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099327-179229684 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 31.7;TIME: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Supported Nucleoplasm Nucleoplasm "CAB017106: , HPA001866: AB_1078082, HPA072754: " "unprognostic (3.05e-1)" "prognostic unfavourable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavourable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavourable (8.40e-4)" 14.3 5.2 8.6 7.4 13.7 3.7 8.3 14.9 10.6 9.2 6.6 5.8 4.5 4.0 5.4 4.7 3.9 4.3 18.8 6.8 9.7 3.9 4.9 4.3 11.5 3.7 6.5 6.1 5.6 8.4 9.2 8.4 6.1 8.1 5.1 5.2 5.8 4.5 4.4 5.2 6.6 3.7 6.9 6.2 3.9 4.7 9.2 8.6 3.6 5.8 3.1 3.6 6.7 11.2 2.8 2.0 3.8 1.2 1.8 2.2 0.6 10.0 5.5 3.7 2.5 3.2 7.3 2.3 11.1 9.1 13.7 9.9 4.0 3.1 5.8 8.2 7.9 5.0 5.2 3.7 19.4 3.6 4.8 2.8 5.0 2.0 5.8 3.1 0.9 6.7 4.9 19.4 31.7 15.1 6.6 1.7 17.7 2.6 2.4 1.6 3.6 1.8 3.7 6.2 2.8 4.6 1.6 2.3 5.1 9.2 2.9 22.8 2.6 2.6 29.5 14.2 10.6 6.8 17.8 3.1 3.8 6.0 6.7 1.7 13.7 3.8 1.2 0.4 2.2 0.4 1.0 1.8 1.4 1.4 0.9 2.8 1.9 2.0 2.6 1.8 0.5 2.0 0.8 0.6 8.6 13.7 14.9 10.6 9.7 3.9 6.5 6.1 8.1 8.6 AC008397.2 ENSG00000285188 "CAMP-specific 3',5'-cyclic phosphodiesterase 4C " Q08493 19 18207961-18255419 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 22.4;intestine: 15.6;pancreas: 14.2" "Cell line enhanced" "Detected in some" "BEWO: 3.6;U-2197: 1.6;U-87 MG: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA048975 Uncertain "HPA048975: " 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.2 1.9 15.6 0.0 0.0 1.3 1.1 3.6 4.0 1.0 22.4 0.6 0.0 0.6 0.0 2.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.8 0.0 0.0 1.7 0.0 2.1 1.1 3.7 0.0 8.0 0.6 0.0 0.4 7.1 0.2 0.0 0.0 0.4 0.8 4.1 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 3.6 0.1 0.0 0.0 0.2 0.0 0.3 0.3 0.3 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.9 0.0 0.0 0.2 0.4 0.0 0.8 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 1.6 0.0 0.3 0.2 0.1 4.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.1" "Cell line enhanced" "Detected in all" "SK-BR-3: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Enhanced Peroxisomes 4300000 Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favourable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favourable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favourable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favourable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" 9.5 12.7 11.0 5.6 11.9 9.6 10.2 8.1 14.3 6.7 16.1 12.5 10.6 23.4 4.9 13.3 12.1 4.6 16.0 17.7 10.2 8.9 48.7 152.1 8.2 5.9 14.0 9.4 5.0 19.2 7.4 5.9 6.8 11.0 13.4 12.4 7.3 11.5 9.4 9.8 6.2 23.8 4.8 12.7 10.0 8.5 4.4 10.9 5.7 9.3 10.1 10.2 9.4 7.0 9.2 47.0 32.8 45.2 17.8 19.3 18.8 8.4 9.2 3.1 9.9 13.6 7.9 10.9 7.8 11.3 8.9 8.5 12.3 9.5 5.0 5.6 12.4 5.6 8.5 13.1 4.9 7.3 8.8 6.5 8.1 34.8 8.8 14.8 14.5 14.7 9.4 7.6 5.5 12.0 6.0 5.9 9.9 11.0 14.3 10.6 3.3 11.2 3.3 6.0 8.4 25.1 25.1 2.7 4.2 7.6 85.3 5.4 8.8 11.9 8.7 5.4 5.2 10.7 10.6 7.8 5.0 3.9 8.8 12.9 8.5 15.3 29.9 32.8 13.6 40.7 11.4 9.2 13.1 13.3 47.0 8.7 13.0 12.1 20.4 17.8 45.2 27.7 19.3 18.8 11.0 11.9 8.1 14.3 10.2 8.9 14.0 9.4 11.0 10.9 ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782167-49813960 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 245.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria 3200000 Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavourable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favourable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 22.7 12.9 9.4 6.9 10.7 4.4 13.0 3.6 7.0 4.1 27.2 8.0 7.8 25.9 5.1 5.1 7.1 4.1 9.2 38.9 6.8 7.0 60.3 245.7 7.9 7.5 10.7 6.1 6.4 13.6 6.3 7.1 7.5 6.7 7.9 18.4 9.5 3.3 6.2 22.9 4.2 37.0 11.3 9.7 6.9 6.0 6.5 7.5 8.4 15.7 8.8 5.0 8.1 4.9 13.0 31.8 27.5 33.0 35.5 40.9 28.6 0.7 13.9 23.2 21.2 30.7 16.2 11.8 7.1 11.6 12.0 9.3 29.5 12.0 12.4 15.2 26.1 0.9 38.6 4.5 11.9 37.9 9.1 8.8 18.1 34.9 14.5 0.1 16.6 21.4 1.5 19.4 6.1 19.6 7.6 11.7 33.2 16.0 0.5 19.1 21.0 5.6 30.4 49.6 45.4 40.5 0.6 33.3 26.4 0.5 16.3 1.1 9.2 12.8 9.3 10.2 12.9 15.4 7.7 23.8 27.4 31.6 7.3 17.9 9.3 13.1 25.9 27.5 32.1 33.0 40.9 13.0 19.2 28.6 31.8 9.7 16.4 24.3 2.5 35.5 31.1 14.9 22.6 28.6 9.4 10.7 3.6 7.0 6.8 7.0 10.7 6.1 6.7 7.5 ACACA "ACAC, ACC, ACC1" ENSG00000278540 "Acetyl-CoA carboxylase alpha" Q13085 17 37084988-37406818 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013715, HPA036650, HPA063018" Approved Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" Cytosol "Nucleoli fibrillar center, Actin filaments" "CAB013715: , HPA036650: , HPA063018: " "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.04e-2)" "unprognostic (1.10e-1)" "unprognostic (4.86e-2)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.24e-5)" "unprognostic (8.81e-2)" "unprognostic (6.56e-2)" "unprognostic (2.38e-3)" "unprognostic (3.38e-1)" "unprognostic (2.24e-1)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (4.89e-1)" "unprognostic (4.49e-2)" "unprognostic (2.03e-2)" 10.7 4.8 5.6 2.5 7.7 3.0 18.5 6.0 11.5 5.3 4.2 6.9 12.7 3.8 4.5 11.7 9.2 3.8 3.6 2.3 4.9 3.0 5.8 7.3 3.5 6.3 4.6 4.3 2.3 13.6 7.9 2.6 6.1 12.2 5.1 4.8 4.6 14.4 11.3 5.4 2.5 7.8 4.2 2.3 3.9 5.5 5.7 2.0 4.2 4.5 5.0 4.3 4.6 4.4 3.2 1.3 4.1 2.0 3.9 2.0 14.6 3.0 17.9 18.8 25.0 24.7 6.2 6.6 9.3 6.8 12.4 11.9 2.5 2.0 5.4 10.5 15.2 3.3 22.3 10.7 5.8 9.8 11.7 7.7 12.1 4.0 6.3 2.4 19.9 13.0 18.1 13.5 12.0 27.9 1.4 1.0 12.4 6.7 9.7 13.6 9.7 10.3 11.3 2.7 16.2 16.7 20.3 8.0 11.8 5.5 5.2 11.1 7.2 10.6 5.8 9.3 8.1 1.6 3.9 4.7 18.3 5.3 5.3 8.0 1.1 2.8 0.3 2.3 4.1 2.1 2.7 2.5 2.7 3.2 4.4 3.9 2.7 1.3 2.0 2.7 2.4 3.2 2.0 ACACB "ACC2, ACCB, HACC275" ENSG00000076555 "Acetyl-CoA carboxylase beta" O00763 12 109116595-109268226 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "adipose tissue: 104.5;breast: 67.4;liver: 42.0;skeletal muscle: 154.2" "Cell line enriched" "Detected in many" 18 "ASC diff: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 15.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006554 Enhanced "Intracellular and membrane" "HPA006554: AB_1844495" "unprognostic (2.24e-1)" "unprognostic (4.66e-1)" "unprognostic (3.97e-2)" "unprognostic (4.54e-6)" "unprognostic (2.82e-1)" "unprognostic (1.59e-2)" "unprognostic (8.62e-3)" "unprognostic (5.81e-2)" "unprognostic (2.86e-1)" "unprognostic (1.63e-2)" "prognostic favourable (1.93e-4)" "unprognostic (6.63e-2)" "prognostic favourable (1.15e-5)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.21e-3)" "unprognostic (2.58e-2)" 104.5 8.2 4.3 10.6 4.0 1.6 67.4 3.3 3.5 3.5 19.3 3.2 6.2 3.8 4.6 4.3 4.9 3.9 10.5 12.1 4.5 2.0 5.4 42.0 3.1 4.0 6.4 2.7 6.8 8.5 8.9 7.1 1.3 3.7 3.6 3.9 4.0 5.8 9.0 154.2 2.8 4.8 7.5 6.5 2.5 5.6 1.6 4.9 0.4 6.2 12.5 1.7 7.3 6.3 2.5 0.2 15.5 0.4 0.1 1.7 0.1 0.2 1.7 1.1 2.1 71.5 0.5 0.8 0.2 0.4 0.3 0.2 1.2 0.3 0.8 0.5 0.3 1.4 0.9 0.4 0.2 1.1 1.6 2.0 1.8 1.2 0.3 1.7 0.5 0.8 0.4 0.7 0.1 0.1 0.2 0.1 0.2 0.5 1.2 1.6 1.2 3.8 0.6 1.5 0.4 0.5 0.6 0.7 1.7 1.8 0.8 1.1 0.8 1.7 0.1 0.7 0.4 0.8 0.6 2.7 1.5 1.2 1.7 1.3 0.5 4.1 0.4 15.5 1.1 0.1 0.6 1.7 1.0 0.3 0.2 2.5 1.7 0.9 0.6 0.1 0.2 0.2 0.6 0.1 4.3 4.0 3.3 3.5 4.5 2.0 6.4 2.7 3.7 4.9 ACADL "ACAD4, LCAD" ENSG00000115361 "Acyl-CoA dehydrogenase long chain" P28330 2 210187939-210225491 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 29.5;thyroid gland: 29.7" "Cell line enhanced" "Detected in some" "HAP1: 3.1;HEK 293: 2.4;HeLa: 7.3;RPTEC TERT1: 6.6;RT4: 2.5;U-2 OS: 3.7" "Group enriched" "Detected in many" 8 "liver cancer: 2.2;prostate cancer: 6.8;renal cancer: 8.8;thyroid cancer: 4.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011990 Enhanced Supported "HPA011990: AB_1844465" "unprognostic (6.29e-3)" "unprognostic (7.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (1.33e-2)" "unprognostic (7.66e-3)" "unprognostic (3.24e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.99e-1)" "prognostic favourable (1.58e-11)" "unprognostic (4.22e-3)" "unprognostic (1.18e-4)" "unprognostic (8.81e-3)" "unprognostic (1.06e-1)" 9.6 1.1 2.0 1.0 1.8 0.0 10.7 1.4 1.8 3.2 0.8 1.5 4.5 0.1 0.7 6.8 1.3 2.3 2.1 2.2 2.4 1.0 17.3 23.0 29.5 0.0 1.6 2.3 12.2 19.3 11.6 5.8 1.2 3.4 14.5 0.2 3.2 9.9 4.8 7.0 2.2 0.3 1.5 3.1 0.0 3.3 4.2 0.9 0.7 29.7 3.7 0.0 0.7 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.3 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.4 0.0 0.0 2.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.6 0.0 0.0 0.0 6.6 2.5 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.8 1.4 1.8 2.4 1.0 1.6 2.3 3.4 0.9 ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724347-75787575 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.7;skeletal muscle: 82.8" "Cell line enhanced" "Detected in all" "Daudi: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Enhanced Mitochondria 1200000 Mitochondria "HPA006198: AB_1078087, HPA026542: AB_1844469" "unprognostic (9.04e-3)" "unprognostic (2.36e-1)" "prognostic favourable (7.30e-4)" "unprognostic (5.09e-3)" "unprognostic (1.61e-3)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (4.95e-2)" "unprognostic (9.40e-3)" "unprognostic (3.35e-1)" "prognostic favourable (3.83e-8)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-1)" 18.1 25.0 12.3 11.3 13.0 3.9 18.0 12.0 10.8 8.4 21.6 8.3 10.1 25.1 6.7 8.6 21.9 7.6 6.7 49.7 10.5 11.2 71.1 89.7 6.3 9.4 13.0 9.2 10.5 10.3 8.1 12.0 4.2 14.3 9.2 12.1 8.0 9.0 11.7 82.8 5.6 25.1 9.8 10.7 12.3 12.0 8.5 11.0 11.0 12.2 42.1 10.0 9.5 8.1 29.7 16.7 14.1 13.8 16.8 20.0 13.2 6.9 5.5 17.4 7.6 15.0 12.3 4.9 13.0 10.6 12.8 10.8 10.3 11.1 75.9 11.5 9.3 6.4 14.7 11.0 15.9 29.3 7.2 24.9 16.9 15.8 10.5 21.2 6.9 14.2 6.4 11.1 6.7 10.0 25.3 17.2 13.7 2.6 24.9 10.0 14.0 13.3 32.5 22.9 7.9 21.2 18.3 9.4 11.9 10.5 31.4 27.1 9.3 26.9 5.4 8.7 8.6 7.4 21.3 11.2 16.0 33.7 7.4 17.3 9.9 10.7 9.6 14.1 13.2 13.8 20.0 29.7 13.8 15.9 14.3 18.0 15.8 17.6 0.8 16.8 12.7 16.7 13.8 13.2 12.3 13.0 12.0 10.8 10.5 11.2 13.0 9.2 14.3 11.0 ACADS "ACAD3, SCAD" ENSG00000122971 "Acyl-CoA dehydrogenase short chain" P16219 12 120725735-120740008 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.4;skeletal muscle: 50.7" "Cell line enhanced" "Detected in many" "HMC-1: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004799, CAB019284, HPA022271" Enhanced Enhanced Nucleoplasm,Mitochondria 15000 Mitochondria Nucleoplasm "CAB019284: , HPA004799: AB_1844471, HPA022271: AB_1844472" "unprognostic (7.14e-2)" "unprognostic (3.03e-3)" "unprognostic (8.15e-2)" "prognostic favourable (5.05e-4)" "unprognostic (1.11e-3)" "unprognostic (5.75e-2)" "prognostic favourable (2.43e-4)" "unprognostic (5.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.14e-1)" "unprognostic (2.69e-2)" "unprognostic (4.04e-2)" "prognostic favourable (3.33e-6)" "unprognostic (1.23e-2)" "unprognostic (1.81e-1)" "unprognostic (1.21e-1)" "prognostic favourable (6.34e-5)" 19.5 14.5 5.7 10.0 5.2 5.3 18.0 2.3 4.6 2.9 26.2 4.7 4.5 35.8 2.8 5.3 5.0 2.9 9.1 32.6 3.7 3.3 13.2 58.4 5.6 7.8 5.0 4.1 2.3 14.4 3.0 2.4 4.3 3.8 4.1 9.0 5.6 8.9 4.6 50.7 3.4 35.3 6.5 3.8 8.6 9.5 10.7 5.4 4.0 8.1 16.8 4.3 5.0 3.2 6.8 11.4 7.2 14.0 15.3 14.7 10.0 2.0 7.2 0.4 6.3 8.6 3.4 7.3 3.0 3.0 3.9 2.9 5.6 5.1 0.2 7.8 2.5 3.3 4.3 1.3 0.5 10.5 5.3 5.2 2.2 12.0 6.2 0.4 23.7 10.3 2.0 1.7 0.1 4.0 4.2 0.0 1.7 4.2 7.2 12.0 1.3 3.0 5.4 2.7 1.4 7.3 11.6 0.7 4.0 6.2 0.0 9.9 5.0 8.2 4.4 0.1 3.1 3.0 0.6 10.1 5.7 2.5 6.7 4.4 2.6 7.2 13.0 6.4 12.4 14.0 8.8 5.9 11.3 13.0 11.4 6.8 14.7 13.2 1.3 15.3 8.7 9.5 11.9 10.0 5.7 5.2 2.3 4.6 3.7 3.3 5.0 4.1 3.8 5.4 ACADSB "ACAD7, SBCAD" ENSG00000196177 "Acyl-CoA dehydrogenase short/branched chain" P45954 10 123008979-123058311 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 28.9;liver: 114.2" "Cell line enhanced" "Detected in all" "Hep G2: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041458 Enhanced Supported Mitochondria 63000 Mitochondria "HPA041458: " "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" "unprognostic (3.91e-3)" "unprognostic (2.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.87e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-3)" "unprognostic (1.30e-1)" "unprognostic (3.67e-1)" "prognostic favourable (3.40e-4)" "unprognostic (9.37e-3)" "prognostic favourable (6.37e-12)" "unprognostic (2.69e-1)" "unprognostic (7.20e-2)" "unprognostic (1.60e-3)" "unprognostic (7.14e-2)" 4.6 9.4 6.7 2.4 9.0 1.4 8.3 10.3 8.3 3.9 5.3 5.5 6.4 16.8 4.1 3.3 4.4 4.1 3.1 13.7 8.5 4.8 28.9 114.2 4.3 2.7 5.1 8.2 5.0 5.3 8.0 4.9 1.9 7.5 7.9 5.8 4.9 5.6 6.0 12.7 4.7 5.5 5.2 4.8 2.7 4.8 2.9 5.4 3.6 4.3 7.9 3.9 5.0 4.1 6.3 6.8 13.5 5.0 9.0 11.7 6.0 9.5 6.8 5.1 9.3 7.0 8.7 4.5 5.9 12.0 5.9 6.0 6.0 3.1 10.0 4.1 5.0 4.0 7.9 4.1 9.9 6.5 8.2 5.2 2.1 34.6 4.9 7.3 5.0 6.4 4.2 3.7 3.4 5.7 5.0 7.4 7.4 4.4 7.0 6.1 3.1 4.3 8.3 10.7 3.1 8.5 10.6 1.0 5.9 9.1 2.7 9.3 8.3 3.6 6.0 3.2 2.9 7.4 7.1 8.3 9.4 5.3 5.0 7.0 2.4 13.5 5.0 12.3 10.0 5.0 11.7 5.9 9.4 8.6 6.8 6.3 8.9 9.9 3.2 9.0 3.0 4.1 7.6 6.0 6.7 9.0 10.3 8.3 8.5 4.8 5.1 8.2 7.5 5.4 ACADVL "ACAD6, LCACD, VLCAD" ENSG00000072778 "Acyl-CoA dehydrogenase very long chain" P49748 17 7217125-7225273 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019006, HPA020595" Enhanced Supported Nucleoplasm,Nucleoli,Mitochondria,Cytosol 19000000 "Nucleoli, Mitochondria" "Nucleoplasm, Cytosol" "HPA019006: AB_1844478, HPA020595: AB_1844479" "unprognostic (4.81e-2)" "unprognostic (2.86e-1)" "unprognostic (2.21e-2)" "unprognostic (1.09e-2)" "unprognostic (6.63e-3)" "unprognostic (1.51e-1)" "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "prognostic favourable (6.87e-4)" "unprognostic (3.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-1)" "unprognostic (4.01e-1)" "unprognostic (2.84e-3)" 32.7 69.2 22.8 18.2 21.1 15.1 24.1 19.8 18.4 21.1 44.0 16.5 26.7 51.7 17.4 19.7 31.5 14.2 24.4 118.2 20.2 12.2 35.2 90.0 17.3 9.8 18.5 16.8 15.5 67.8 31.5 32.3 40.2 20.9 22.1 24.2 20.0 27.4 29.0 132.3 20.3 51.2 25.0 15.7 21.9 28.7 11.5 18.6 14.6 29.6 36.9 21.2 22.4 31.8 8.3 32.0 37.9 29.0 11.6 14.9 20.0 33.2 31.9 13.1 18.0 56.6 20.8 24.8 24.5 34.1 28.0 17.4 12.9 30.2 17.8 20.5 51.4 25.7 8.8 26.8 24.8 56.5 9.0 9.5 22.7 19.6 27.2 9.0 24.8 23.2 24.6 23.4 36.9 25.1 12.2 21.8 44.9 12.6 9.4 10.9 6.2 12.6 13.1 14.5 42.4 62.2 30.4 3.5 8.6 34.6 44.0 20.1 20.2 13.9 25.0 24.8 18.6 12.5 23.9 20.4 9.5 0.9 45.6 16.0 18.0 6.8 29.0 37.9 13.5 18.0 12.4 8.3 10.9 14.9 32.0 7.6 8.3 10.2 6.3 11.6 12.0 26.0 9.7 20.0 22.8 21.1 19.8 18.4 20.2 12.2 18.5 16.8 20.9 18.6 ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108121516-108147776 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 267.1" "Cell line enhanced" "Detected in all" "RPMI-8226: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria 870000 Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favourable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favourable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" 18.8 28.5 8.9 6.9 9.5 5.4 16.9 5.6 11.6 8.5 16.8 8.5 9.4 15.5 8.8 8.9 8.8 7.6 5.1 53.8 7.4 7.4 88.8 267.1 7.3 6.0 9.9 9.9 10.3 27.3 14.3 6.3 3.8 22.4 7.6 13.1 10.6 27.1 15.9 65.0 8.2 10.9 16.4 8.1 7.7 13.9 14.2 7.2 1.7 10.1 32.1 5.2 12.3 6.9 18.8 20.2 2.3 14.7 7.7 20.7 11.6 15.8 13.0 10.3 29.6 33.3 29.5 5.7 15.2 16.3 16.5 19.3 35.8 16.4 8.8 26.2 17.0 16.8 29.8 14.4 18.0 17.5 24.4 25.3 14.8 32.5 23.0 23.9 15.0 26.7 16.0 14.4 27.0 17.5 35.1 13.1 26.3 9.1 14.1 22.3 10.1 29.1 19.7 20.3 85.2 22.6 10.4 16.5 19.6 24.8 32.2 16.6 27.5 19.6 19.5 17.8 10.4 16.2 18.3 4.4 12.9 16.5 7.9 47.9 12.6 0.8 9.8 2.3 15.6 14.7 17.7 18.8 17.6 17.5 20.2 10.2 15.5 14.3 1.0 7.7 14.4 7.0 20.7 11.6 8.9 9.5 5.6 11.6 7.4 7.4 9.9 9.9 22.4 7.2 ACAT2 ENSG00000120437 "Acetyl-CoA acetyltransferase 2" Q9BWD1 6 159760328-159779055 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 20.4;liver: 31.0" "Cell line enhanced" "Detected in all" "HBEC3-KT: 48.0" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021106, HPA025736, HPA025765, HPA025811" Enhanced Supported Nucleoplasm,Cytosol 16000000 Cytosol Nucleoplasm "CAB021106: AB_10058215, HPA025736: AB_1844487, HPA025765: AB_1844485, HPA025811: AB_1844488" "unprognostic (3.31e-1)" "unprognostic (2.44e-2)" "prognostic favourable (1.12e-4)" "prognostic unfavourable (7.25e-4)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (9.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "prognostic unfavourable (7.38e-4)" "unprognostic (1.39e-1)" "unprognostic (1.50e-2)" "unprognostic (8.56e-2)" "unprognostic (2.54e-2)" 1.6 2.6 2.7 1.5 1.7 1.6 2.2 2.2 6.3 2.1 4.3 3.2 1.4 4.8 5.7 1.0 0.7 0.7 2.9 3.6 3.0 31.0 1.8 2.5 2.9 2.1 0.7 1.3 1.2 0.9 4.2 3.9 2.3 0.5 0.1 2.4 1.6 1.4 5.1 1.1 1.7 6.6 0.9 4.2 1.1 2.6 13.3 9.5 12.3 8.4 10.0 20.4 12.2 6.9 6.5 44.3 16.9 6.3 11.8 1.5 6.2 7.3 14.7 25.4 25.4 8.9 5.9 3.1 4.8 6.7 18.3 48.0 17.4 3.5 18.8 13.6 10.6 42.2 6.4 7.8 3.7 6.4 3.5 24.2 10.4 7.1 14.6 9.9 8.9 12.4 13.5 12.5 14.9 4.8 8.4 9.9 18.0 34.2 9.1 11.9 6.7 7.1 4.6 2.4 8.9 15.7 4.4 5.4 4.7 7.6 15.8 4.7 8.7 14.4 1.6 15.5 8.1 6.1 7.1 12.3 13.9 8.4 13.7 13.3 15.9 13.8 9.5 13.3 16.0 12.3 3.2 10.0 5.6 8.7 20.4 12.2 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 205.6" "Group enriched" "Detected in some" 4 "ASC TERT1: 35.9;HUVEC TERT2: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "memory B-cell: 3.7" "Group enriched" "Detected in many" 23 "B-cells: 3.7;monocytes: 2.0;T-cells: 1.9" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" 121920000 92000000 Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: " "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 6.8 2.0 0.5 2.4 4.2 0.0 2.9 0.5 1.1 5.3 83.2 0.7 37.7 46.4 4.5 5.1 1.7 1.5 4.4 4.7 0.6 0.7 2.6 1.4 16.3 2.2 0.4 0.7 1.4 3.0 3.6 3.6 3.6 0.8 3.4 1.4 1.7 2.5 20.1 3.6 1.3 205.6 2.4 0.6 1.4 1.9 32.6 1.3 0.5 6.9 3.1 2.2 1.7 1.6 3.7 0.1 0.0 2.0 0.0 1.9 0.4 0.0 0.0 0.0 0.0 1.5 35.9 0.4 1.3 2.6 0.0 0.0 0.5 3.1 0.7 1.0 6.1 0.0 1.7 0.0 0.0 0.0 0.7 3.4 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 18.3 3.0 0.0 0.0 0.6 0.0 0.7 0.2 0.3 0.1 0.2 0.5 0.0 0.0 4.5 3.2 0.0 0.0 0.0 1.6 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.4 0.6 0.9 3.7 1.9 1.4 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.4 0.5 4.2 0.5 1.1 0.6 0.7 0.4 0.7 0.8 1.3 ACE2 ENSG00000130234 "Angiotensin I converting enzyme 2" Q9BYF1 X 15561033-15602148 "Enzymes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 122.0" "Cell line enhanced" "Detected in some" "BEWO: 2.4;HaCaT: 4.1;Hep G2: 2.4;NB-4: 2.2;RPMI-8226: 2.0;RT4: 2.4;SH-SY5Y: 2.8" "Cancer enhanced" "Detected in many" "renal cancer: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174" Enhanced "Secreted to blood" 85000 "CAB026174: , HPA000288: AB_1078160" "unprognostic (1.40e-1)" "unprognostic (7.26e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (2.51e-1)" "unprognostic (5.26e-2)" "prognostic favourable (4.21e-4)" "unprognostic (2.34e-2)" "unprognostic (6.74e-3)" "unprognostic (2.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "prognostic favourable (2.12e-5)" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (7.10e-2)" 4.5 0.4 0.2 0.8 0.2 0.0 2.3 0.2 0.2 0.4 49.1 0.2 2.3 46.0 0.4 2.7 1.2 0.6 16.4 10.5 0.2 0.1 23.2 1.2 0.8 0.6 0.2 0.2 1.3 1.6 0.0 0.2 1.0 0.2 0.5 1.3 0.2 1.1 1.2 0.7 0.2 122.0 0.3 0.2 0.2 0.5 17.9 0.2 0.2 4.5 0.5 0.2 0.4 0.9 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.4 0.0 0.7 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.6 0.0 4.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.2 0.0 0.0 2.0 0.4 2.4 0.6 2.8 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 43.8;skeletal muscle: 98.2" "Cell line enhanced" "Detected in some" "BEWO: 8.0;CACO-2: 12.6;K-562: 14.8;Karpas-707: 24.7;U-2 OS: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" 650000 "Golgi apparatus" Vesicles "HPA027098: " "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavourable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavourable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" 1.4 4.8 5.8 3.5 16.1 10.3 1.4 22.8 11.8 1.4 4.2 2.7 1.4 5.7 1.9 2.6 2.8 1.8 3.1 4.5 5.5 43.8 1.4 1.8 1.8 5.9 22.2 4.8 1.7 1.6 7.0 3.2 2.0 37.9 3.3 3.4 4.6 6.5 3.3 98.2 1.4 7.9 1.9 8.7 2.3 2.1 1.9 2.6 3.5 1.6 15.9 3.2 2.1 1.2 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.3 0.2 0.5 0.0 8.0 0.3 0.0 0.1 0.2 12.6 0.3 0.0 0.4 0.0 0.4 2.1 0.1 0.0 4.3 0.5 0.2 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.0 14.8 24.7 0.1 3.5 0.0 0.1 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 1.4 0.0 1.0 0.0 0.0 0.0 0.1 0.7 5.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 16.1 22.8 11.8 5.5 43.8 22.2 4.8 37.9 2.6 ACLY "ACL, ATPCL, CLATP" ENSG00000131473 "ATP citrate lyase" P53396 17 41866908-41930542 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007783, HPA022434, HPA022953, HPA022959, HPA028758" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" 2100000 "Plasma membrane, Cytosol" Nucleoplasm "CAB007783: AB_562242, HPA022434: AB_1844513, HPA022953: AB_1844514, HPA022959: AB_1844515, HPA028758: AB_10603575" "unprognostic (2.21e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (1.41e-1)" "unprognostic (1.21e-2)" "unprognostic (2.83e-1)" "unprognostic (8.94e-3)" "prognostic unfavourable (3.66e-4)" "unprognostic (3.38e-3)" "unprognostic (4.11e-2)" "unprognostic (5.94e-3)" "unprognostic (2.13e-2)" "unprognostic (3.01e-2)" "unprognostic (3.88e-3)" "unprognostic (1.66e-1)" "unprognostic (9.36e-2)" "unprognostic (3.90e-2)" "unprognostic (4.67e-3)" 38.3 24.0 16.7 26.2 22.9 19.1 35.7 21.5 29.1 22.9 22.2 25.1 18.0 30.7 27.0 24.9 23.2 23.7 28.2 18.4 18.3 33.7 37.8 22.2 23.3 27.4 23.1 17.9 19.0 30.6 27.1 19.5 26.7 49.0 41.3 23.2 15.6 25.4 19.6 10.9 19.6 29.6 27.2 26.2 24.5 24.6 20.7 21.4 32.0 21.3 18.2 24.6 20.3 21.3 16.1 23.9 25.2 26.3 16.0 23.9 21.4 23.2 79.1 37.4 32.2 57.8 54.3 34.4 32.7 35.8 41.2 51.8 40.1 26.8 37.8 21.0 45.8 37.0 48.2 56.0 34.5 34.0 46.1 21.6 45.6 41.7 26.9 34.9 28.3 43.1 16.9 72.4 14.6 43.4 26.6 30.2 34.1 23.7 57.4 19.6 24.3 14.4 37.7 45.2 48.4 42.2 41.4 70.4 38.7 23.3 73.0 25.0 43.5 33.4 46.6 32.2 26.5 32.3 53.6 17.7 22.5 35.9 54.4 27.1 26.1 18.9 20.7 25.2 23.8 22.1 22.5 16.1 19.0 21.3 23.9 13.8 14.6 16.1 10.7 16.0 26.3 13.9 23.9 21.4 16.7 22.9 21.5 27.7 18.3 33.7 23.1 17.9 49.0 21.4 ACMSD ENSG00000153086 "Aminocarboxymuconate semialdehyde decarboxylase" Q8TDX5 2 134838547-134902034 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "kidney: 44.8;liver: 64.1" "Cell line enriched" "Detected in some" 22 "RPTEC TERT1: 24.2" "Group enriched" "Detected in some" 23 "liver cancer: 21.2;renal cancer: 19.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA010533, HPA011179" Enhanced 11000 "HPA010533: AB_1844517, HPA011179: AB_1844516" "unprognostic (1.06e-2)" "unprognostic (5.30e-2)" "unprognostic (1.40e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-1)" "unprognostic (5.35e-4)" "unprognostic (7.60e-2)" "unprognostic (5.17e-2)" "unprognostic (2.44e-3)" "prognostic favourable (2.39e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (2.93e-2)" "unprognostic (2.65e-5)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 2.5 0.0 0.0 0.0 44.8 64.1 0.1 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 1.4 0.9 0.6 0.2 1.7 0.5 0.3 0.1 0.4 0.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.7 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.6 0.2 1.0 0.4 0.1 0.5 0.2 24.2 0.3 0.9 0.3 0.1 0.2 0.4 0.2 0.6 0.8 0.0 0.3 0.2 0.7 0.1 0.1 0.4 0.1 0.2 0.6 0.0 0.6 0.9 0.9 0.5 0.4 1.5 0.9 1.3 0.9 1.1 1.7 0.9 0.4 0.2 0.5 1.4 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.9" "Cell line enhanced" "Detected in many" "ASC diff: 52.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol 8000000 "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favourable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 41.4 27.2 9.6 7.1 9.4 1.5 30.1 8.9 8.1 9.3 19.7 6.2 6.4 21.9 12.8 14.6 12.8 7.2 8.9 15.1 6.5 7.6 40.5 80.9 9.2 9.4 6.1 6.2 14.1 27.9 8.9 8.7 11.3 7.7 10.7 9.8 11.7 11.7 9.5 11.2 5.5 28.4 14.5 6.0 6.4 13.5 11.4 5.9 6.0 18.4 7.2 5.1 13.9 11.7 4.7 7.1 21.4 8.8 4.7 7.4 6.2 9.4 8.7 6.7 10.6 52.5 28.5 3.0 17.9 44.1 8.2 6.5 9.1 2.9 1.9 5.7 18.7 1.3 13.3 17.1 16.6 6.0 3.6 13.8 9.4 9.9 26.4 1.3 5.6 24.8 5.3 21.2 15.0 21.3 4.9 4.1 23.4 2.4 7.3 6.6 7.0 9.2 5.7 10.0 1.9 31.4 8.7 0.8 2.8 18.6 0.7 1.9 4.3 3.4 23.0 30.1 10.2 10.0 4.6 2.0 3.8 3.7 21.0 4.6 2.6 21.4 8.7 2.4 7.4 8.8 6.4 4.7 5.2 5.7 7.1 4.2 6.8 7.0 1.0 4.7 7.2 3.4 2.8 6.2 9.6 9.4 8.9 8.1 6.5 7.6 6.1 6.2 7.7 5.9 ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41469125-41528989 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 121.0;skeletal muscle: 157.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria 4000000 Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favourable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" 22.8 18.5 41.4 11.1 38.2 9.8 12.2 21.0 43.5 12.2 25.4 27.7 12.3 45.1 9.5 9.9 17.5 15.7 11.1 121.0 33.8 24.2 37.9 22.2 10.0 11.1 27.6 32.7 8.6 17.2 48.5 7.6 9.1 24.9 12.5 20.0 14.7 20.1 15.2 157.9 9.8 46.6 12.5 28.6 10.0 21.0 9.6 23.1 9.5 16.0 42.7 12.0 12.3 8.8 22.9 28.1 7.3 36.6 15.8 16.4 19.4 16.1 18.8 18.9 39.0 32.6 21.3 26.5 14.9 18.8 25.1 23.5 27.7 21.1 37.1 24.4 22.1 37.1 35.1 27.2 13.2 24.5 25.0 18.0 26.3 29.4 28.5 47.9 27.6 37.8 21.9 26.0 27.7 24.8 23.2 40.5 19.7 30.3 24.4 16.2 12.9 37.7 33.2 13.0 51.4 32.3 32.1 13.6 11.6 36.6 43.3 27.6 25.1 25.6 17.6 21.4 24.0 19.5 16.3 24.1 29.9 25.9 34.6 20.9 23.1 4.5 21.1 7.3 14.7 31.3 14.0 22.9 12.5 15.8 28.1 20.2 14.2 14.6 5.3 15.8 36.6 11.2 16.4 19.4 41.4 38.2 21.0 43.5 33.8 24.2 27.6 32.7 24.9 23.1 ACOD1 "CAD, IRG1" ENSG00000102794 "Aconitate decarboxylase 1" A6NK06 13 76948497-76958642 "Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 3.0;lymphoid tissue: 5.8" "Group enriched" "Detected in some" 6 "PC-3: 1.1;U-87 MG: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040143 Uncertain "HPA040143: AB_10793916" "unprognostic (2.39e-1)" "unprognostic (6.42e-2)" "unprognostic (2.37e-1)" "unprognostic (3.54e-2)" "unprognostic (3.09e-1)" "unprognostic (8.30e-2)" "unprognostic (4.30e-2)" "unprognostic (1.64e-5)" "unprognostic (7.70e-2)" "unprognostic (3.68e-2)" "unprognostic (6.51e-3)" 1.4 0.1 0.0 5.8 0.0 0.6 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.1 0.1 0.0 0.0 0.3 3.0 1.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.8 0.3 0.0 0.6 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537114-73543794 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 27.6" "Cell line enhanced" "Detected in many" "Hep G2: 17.9;T-47d: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA043705 Approved Approved Mitochondria Mitochondria "HPA043705: " "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favourable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 8.5 7.2 5.1 3.7 3.9 1.0 13.7 2.0 7.7 3.0 5.8 4.1 0.9 5.3 6.8 8.8 2.7 3.4 1.8 11.3 4.3 3.6 16.4 27.6 9.0 0.9 3.2 6.0 4.5 1.4 2.9 0.9 4.1 5.6 5.5 3.4 2.4 2.7 6.1 10.7 3.8 12.9 13.0 1.9 1.0 3.4 2.7 2.4 0.9 1.8 5.0 1.9 5.6 1.7 3.8 5.7 1.0 1.7 4.2 6.3 3.1 4.1 5.0 1.9 0.1 9.8 6.0 0.1 1.3 5.3 4.4 8.1 1.9 2.0 0.0 0.0 3.5 2.5 0.0 0.9 2.1 2.3 1.6 2.6 1.2 17.9 9.4 0.1 2.9 7.8 0.4 3.5 0.0 2.0 0.0 0.0 3.4 1.6 0.3 0.5 1.8 1.9 5.1 3.9 0.1 4.3 4.6 2.2 3.8 4.1 12.2 6.7 24.7 6.1 2.2 2.5 3.2 2.2 0.0 0.0 0.0 1.3 3.6 0.0 3.9 0.1 1.3 1.0 6.0 1.7 4.9 3.8 5.5 4.7 5.7 2.6 4.8 5.3 0.2 4.2 1.5 3.2 6.3 3.1 5.1 3.9 2.0 7.7 4.3 3.6 3.2 6.0 5.6 2.4 ACOT12 "Cach, STARD15, THEAL" ENSG00000172497 "Acyl-CoA thioesterase 12" Q8WYK0 5 81330005-81394179 "Enzymes, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 49.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.0;CACO-2: 2.4;Karpas-707: 1.8;SK-MEL-30: 4.1" "Cancer enriched" "Detected in single" 76 "liver cancer: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037723, HPA037724" Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA037723: AB_10672606, HPA037724: " "unprognostic (6.06e-2)" "unprognostic (1.39e-1)" "prognostic favourable (5.30e-4)" "unprognostic (7.68e-2)" "unprognostic (8.22e-2)" "unprognostic (5.68e-3)" "unprognostic (2.46e-1)" "unprognostic (6.86e-2)" "unprognostic (1.46e-2)" "unprognostic (3.07e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.2 49.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.4 0.1 0.0 0.1 2.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 60.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA043705, HPA060170" Enhanced Approved Mitochondria Mitochondria "HPA043705: , HPA060170: " "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favourable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 41.4 16.5 5.9 6.4 5.3 2.7 13.4 3.3 8.7 7.8 11.9 4.6 4.0 12.8 13.9 10.6 9.4 8.3 8.8 35.1 4.5 4.0 25.0 60.5 6.2 4.4 4.3 5.4 6.2 8.1 6.4 2.7 7.9 4.3 8.5 6.2 6.9 7.3 6.8 50.7 3.9 12.0 16.3 3.2 4.3 7.4 5.7 3.7 5.3 7.4 11.6 3.9 11.3 4.6 9.7 13.8 1.8 4.4 9.0 19.0 8.1 11.1 10.9 2.3 9.6 10.2 4.0 0.4 6.0 13.8 9.7 12.9 7.7 7.4 0.0 4.3 3.2 6.1 0.0 0.6 5.1 14.0 13.8 6.7 4.4 26.5 6.6 0.0 19.1 9.0 0.0 3.6 0.0 4.2 0.0 0.0 8.3 4.6 1.0 7.6 3.3 16.5 15.9 9.7 0.1 3.5 4.7 10.0 12.1 14.6 11.4 11.9 27.3 5.4 7.5 8.6 21.4 5.5 5.6 0.0 0.0 4.0 7.1 0.0 8.0 1.5 3.7 1.8 14.6 4.4 10.7 9.7 13.7 11.1 13.8 7.9 12.4 13.5 0.1 9.0 3.9 8.5 19.0 8.1 5.9 5.3 3.3 8.7 4.5 4.0 4.3 5.4 4.3 3.7 ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591706-73596496 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.1;SK-BR-3: 11.4;T-47d: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000779 Enhanced "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavourable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favourable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" 6.3 2.2 2.9 1.4 3.6 0.6 4.4 1.6 5.7 3.6 2.6 1.0 1.5 3.9 1.0 2.4 2.0 0.9 3.3 2.9 2.1 2.0 13.0 15.6 3.9 1.1 1.6 2.8 0.9 2.2 1.1 0.7 4.9 2.7 1.4 3.1 1.8 3.1 3.4 0.7 0.9 7.4 2.5 0.8 1.4 1.9 2.8 0.9 0.3 1.2 0.8 1.2 1.1 1.3 1.7 0.6 5.0 0.4 4.6 10.6 3.2 4.2 1.2 0.1 0.0 0.5 0.2 0.0 0.2 0.0 0.3 0.4 0.1 7.1 0.0 0.2 0.3 0.4 0.0 0.0 0.0 2.2 0.0 0.0 1.5 0.0 0.8 0.0 4.0 0.3 0.5 0.1 0.0 0.1 0.0 0.0 0.2 5.5 0.1 0.7 0.3 1.1 0.0 0.0 0.0 0.1 2.0 0.6 0.1 2.7 11.4 0.8 28.5 4.3 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 1.0 10.6 0.4 5.5 1.6 5.2 6.0 0.2 1.7 3.2 6.5 0.3 4.6 0.2 0.6 4.8 3.2 2.9 3.6 1.6 5.7 2.1 2.0 1.6 2.8 2.7 0.9 ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6394391 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "NK-cell: 20.5;plasmacytoid DC: 19.4" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025735, HPA025762" Enhanced Supported Nucleoplasm,Cytosol 29000 Cytosol Nucleoplasm "HPA025735: AB_1844523, HPA025762: AB_1844524" "unprognostic (3.94e-2)" "unprognostic (1.74e-1)" "unprognostic (7.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.10e-2)" "unprognostic (5.06e-2)" "prognostic unfavourable (2.31e-5)" "prognostic unfavourable (1.29e-4)" "unprognostic (2.35e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavourable (2.55e-6)" "unprognostic (2.68e-2)" "unprognostic (1.45e-1)" "unprognostic (9.06e-2)" "unprognostic (3.72e-2)" 4.7 13.3 25.8 10.8 29.8 7.7 3.9 23.9 50.0 4.4 18.3 11.3 0.5 33.2 5.1 3.8 14.3 4.4 5.3 6.3 27.8 43.9 29.4 9.1 8.6 12.3 36.0 20.7 5.3 4.0 1.9 18.5 7.4 49.9 5.6 13.5 6.6 4.1 4.9 1.5 9.4 33.2 14.3 14.2 8.9 6.2 13.1 6.9 9.0 2.3 6.5 11.6 9.1 6.6 1.0 19.4 0.4 0.6 20.5 4.4 2.8 23.4 20.4 20.2 21.7 4.6 7.7 7.6 20.2 10.5 30.0 18.0 70.5 7.6 28.7 14.9 16.4 23.2 32.5 54.0 11.3 25.2 28.4 15.1 16.2 24.9 19.0 17.6 12.6 6.8 10.3 24.8 29.4 16.8 12.3 6.2 15.8 27.3 36.8 18.7 10.1 47.4 44.1 23.2 19.4 16.8 9.0 11.0 31.3 18.2 28.0 64.4 9.9 8.3 27.2 27.3 16.0 27.1 31.9 5.2 21.4 40.4 17.3 30.9 16.6 0.0 0.1 0.1 4.1 0.6 1.0 1.0 3.4 3.6 2.9 0.4 1.2 2.3 0.4 20.5 0.5 19.4 4.4 2.8 25.8 29.8 23.9 50.0 27.8 43.9 36.0 20.7 49.9 6.9 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857406 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favourable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 7.0 22.6 23.5 10.9 24.3 16.5 8.7 14.4 32.6 6.8 17.1 13.5 9.9 23.3 6.5 13.1 15.8 12.2 10.1 27.0 22.8 19.3 15.3 19.0 9.7 12.1 22.1 19.0 8.3 17.4 5.9 11.4 8.1 19.5 9.6 14.3 10.4 14.4 7.3 21.7 16.7 22.2 7.3 14.6 9.1 16.7 12.8 11.1 17.1 12.4 8.6 12.2 10.9 7.2 20.5 27.0 31.0 26.2 11.2 22.5 18.8 7.6 9.2 3.1 6.3 8.9 5.4 5.5 5.2 4.2 7.3 6.8 13.4 10.7 9.6 23.6 7.1 15.0 6.0 13.0 2.5 7.1 10.6 9.6 12.4 12.8 8.0 9.1 9.0 6.3 9.9 7.0 5.0 4.5 8.5 11.9 5.1 21.5 13.0 11.9 5.6 24.5 6.3 5.8 17.1 7.7 8.7 10.9 5.1 11.5 29.4 17.8 16.1 22.5 5.1 18.1 4.0 9.3 8.6 10.1 15.0 6.0 22.4 9.6 9.6 20.0 26.2 31.0 18.8 25.0 17.1 20.5 18.1 17.0 27.0 19.3 16.1 17.3 18.7 11.2 23.4 17.0 22.5 18.8 23.5 24.3 14.4 32.6 22.8 19.3 22.1 19.0 19.5 11.1 ACOX1 PALMCOX ENSG00000161533 "Acyl-CoA oxidase 1" Q15067 17 75941507-75979363 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 95.6" "Cell line enhanced" "Detected in all" "BEWO: 34.6;RT4: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 22.9;neutrophil: 38.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021094, HPA021192, HPA021195, HPA028759" Approved Approved Nucleoli,Peroxisomes 160000 Peroxisomes Nucleoli "CAB021094: AB_10261667, HPA021192: AB_1844527, HPA021195: AB_1844528, HPA028759: AB_10601352" "unprognostic (7.47e-2)" "unprognostic (3.69e-1)" "unprognostic (1.25e-3)" "unprognostic (1.36e-1)" "unprognostic (7.49e-2)" "unprognostic (8.14e-2)" "unprognostic (3.75e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "prognostic favourable (5.25e-7)" "unprognostic (3.39e-1)" "unprognostic (2.41e-2)" "unprognostic (1.72e-1)" "unprognostic (4.46e-2)" 21.8 12.9 8.8 8.3 10.2 4.2 13.6 6.4 9.8 6.4 26.5 8.2 9.6 31.0 6.6 6.7 19.5 6.0 12.3 16.0 8.3 7.9 20.8 95.6 9.2 7.5 8.2 8.3 7.6 28.7 9.8 8.9 13.6 7.8 9.5 14.3 11.3 9.5 9.1 18.3 13.4 53.1 7.9 6.7 7.2 13.6 6.2 6.3 7.1 9.1 11.4 10.6 10.6 7.9 1.6 3.3 38.6 5.8 2.1 2.7 2.2 5.3 7.6 2.5 3.8 13.0 5.5 34.6 3.9 3.9 4.7 5.4 5.3 8.8 3.1 4.2 6.6 3.2 10.5 4.1 7.4 2.8 3.1 4.0 4.3 17.3 7.1 3.4 2.6 9.1 3.2 5.3 3.5 11.7 4.0 3.0 5.2 15.7 7.4 2.5 1.8 6.5 4.1 7.6 3.6 8.0 46.6 3.0 4.5 11.1 17.5 3.7 10.7 3.8 7.8 6.5 4.8 5.3 3.7 5.0 3.4 1.2 3.8 3.1 3.8 22.9 5.8 1.6 2.1 4.5 2.7 1.6 2.0 2.7 3.3 1.6 2.4 2.3 38.6 2.1 2.8 2.9 2.6 2.2 8.8 10.2 6.4 9.8 8.3 7.9 8.2 8.3 7.8 6.3 ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537319 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 70.5" "Cell line enhanced" "Detected in some" "ASC diff: 12.2;ASC TERT1: 20.2;fHDF/TERT166: 6.6;Hep G2: 7.8;HSkMC: 13.1" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol 190000 Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" 4.0 5.3 1.9 3.8 2.5 0.1 3.4 1.6 2.1 4.4 10.2 2.7 9.5 10.0 9.0 6.2 3.8 4.4 4.8 8.8 2.4 1.4 17.1 70.5 2.8 0.7 2.0 1.7 5.1 2.9 3.8 3.0 1.4 4.0 7.2 3.4 11.4 3.0 5.9 4.2 1.7 13.7 10.6 2.5 0.9 2.6 4.0 2.0 1.0 7.7 2.7 1.6 5.4 5.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.2 20.2 3.5 2.3 0.2 0.0 0.3 0.6 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 1.8 0.0 0.0 13.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.5 1.6 2.1 2.4 1.4 2.0 1.7 4.0 2.0 ACOX3 ENSG00000087008 "Acyl-CoA oxidase 3, pristanoyl" O15254 4 8366282-8440723 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035840, HPA035841" Uncertain Approved Peroxisomes Peroxisomes "HPA035840: AB_10696514, HPA035841: AB_10671940" "unprognostic (3.07e-2)" "unprognostic (5.51e-2)" "unprognostic (1.12e-1)" "prognostic favourable (2.16e-4)" "unprognostic (5.52e-2)" "unprognostic (1.81e-3)" "unprognostic (2.21e-1)" "unprognostic (3.37e-2)" "unprognostic (2.27e-1)" "unprognostic (4.43e-2)" "unprognostic (4.81e-1)" "unprognostic (1.39e-1)" "unprognostic (1.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.84e-1)" "unprognostic (1.69e-1)" "unprognostic (2.65e-1)" 9.6 12.0 9.9 7.4 10.9 5.0 15.5 11.7 12.8 12.2 9.9 11.5 11.2 10.8 10.7 12.3 32.0 9.2 7.4 20.6 9.0 6.7 8.3 18.0 8.9 7.4 10.3 8.4 9.8 15.4 10.0 14.8 28.9 10.2 13.4 8.0 12.0 19.1 11.2 8.2 14.8 10.5 18.6 7.2 7.6 12.7 5.0 11.6 9.0 11.5 7.4 14.2 14.8 16.0 4.6 16.8 2.6 12.0 7.3 8.0 6.9 6.3 6.9 7.8 10.4 8.4 14.3 12.8 8.1 11.1 13.8 12.1 3.4 8.5 8.5 8.8 16.4 3.9 3.4 10.5 10.8 2.9 3.3 3.7 5.8 10.5 13.9 7.5 7.0 14.4 9.0 12.3 4.8 16.2 4.9 7.9 11.8 5.8 8.0 11.1 4.4 12.0 8.4 12.8 10.2 8.5 8.9 3.8 8.8 10.3 5.3 5.3 5.3 10.7 15.7 13.7 4.5 5.5 8.4 5.9 3.9 3.8 17.4 9.5 8.6 0.0 10.6 2.6 5.2 12.0 5.4 4.6 6.1 6.6 14.0 4.5 5.6 5.8 2.5 7.3 10.6 16.8 8.0 6.9 9.9 10.9 11.7 12.8 9.0 6.7 10.3 8.4 10.2 11.6 ACP1 "HAAP, LMW-PTP, LMWPTP" ENSG00000143727 "Acid phosphatase 1" P24666 2 264140-278283 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016754 Approved Approved Nucleoplasm,Cytosol 3700000 Nucleoplasm Cytosol "HPA016754: AB_1844505" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (6.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.43e-1)" "prognostic unfavourable (6.67e-6)" "unprognostic (2.45e-1)" "prognostic unfavourable (3.04e-4)" "unprognostic (9.72e-3)" "unprognostic (4.89e-2)" "unprognostic (2.71e-2)" "unprognostic (7.10e-2)" "unprognostic (2.88e-2)" "unprognostic (3.39e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" 22.3 59.7 38.0 20.8 40.3 38.0 33.0 27.9 43.7 23.1 29.7 27.4 24.4 31.1 25.2 36.2 24.8 29.5 26.9 27.4 34.6 33.7 42.1 54.8 24.7 29.4 31.5 34.6 33.7 53.0 28.4 43.9 39.7 39.7 27.0 32.8 28.5 46.0 23.8 35.4 21.6 34.5 24.2 28.6 28.1 34.2 38.3 21.2 33.0 32.5 32.8 29.8 22.7 20.3 33.9 20.3 17.3 23.0 35.3 41.0 33.1 17.6 26.4 41.1 22.6 18.7 18.7 33.5 21.5 22.9 21.5 19.1 36.1 17.8 11.1 16.8 20.1 17.4 39.9 23.3 19.4 27.0 40.7 32.5 23.9 79.1 25.9 36.9 18.7 19.0 21.3 20.1 24.9 24.4 32.8 21.7 25.4 24.0 39.7 35.7 49.7 29.8 26.3 41.8 25.4 33.6 25.3 44.9 44.5 13.4 31.7 43.0 18.8 19.8 20.1 23.7 15.8 19.5 32.4 29.5 58.6 34.7 28.1 32.0 27.9 17.3 19.8 17.1 30.1 22.7 39.7 33.9 34.3 34.4 17.7 31.1 41.0 39.7 3.5 35.3 23.0 20.3 35.6 33.1 38.0 40.3 27.9 43.7 34.6 33.7 31.5 34.6 39.7 21.2 ACP5 "HPAP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574660-11579008 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 117.9;lung: 151.9" "Cell line enhanced" "Detected in some" "BEWO: 14.3;RPMI-8226: 13.6;SK-MEL-30: 40.4;U-138 MG: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "memory B-cell: 51.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002584, HPA057655, HPA059463" Enhanced Approved Cytosol "Intracellular and membrane" 3700000 Cytosol "CAB002584: AB_564039, HPA057655: , HPA059463: " "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" 117.9 2.8 0.9 21.1 1.1 1.4 7.7 0.7 1.0 11.9 10.2 1.2 2.1 7.7 7.7 6.5 12.1 3.5 9.1 6.8 0.9 0.4 28.0 16.3 151.9 30.8 1.0 1.0 13.2 8.7 0.2 1.6 9.2 1.2 6.4 8.7 19.1 8.6 2.8 3.0 10.4 15.6 3.3 1.9 20.7 15.0 3.5 0.7 9.2 2.2 8.2 18.4 11.4 10.1 51.4 13.9 16.8 9.4 2.6 16.0 8.1 3.2 0.4 0.0 0.0 0.2 0.0 14.3 0.4 9.6 0.0 0.0 0.0 0.1 0.4 0.6 2.8 0.1 0.0 1.4 0.0 3.6 0.3 0.1 0.0 1.7 0.5 0.0 0.2 0.0 1.1 0.1 0.0 0.0 10.0 0.0 0.0 0.7 0.3 0.5 0.3 0.2 0.1 0.7 13.6 0.0 0.1 0.2 0.3 0.0 0.0 40.4 0.0 0.1 0.3 38.0 0.4 0.7 0.1 0.2 1.8 0.2 7.8 0.0 1.2 0.0 9.4 16.8 4.1 9.1 2.1 51.4 6.4 4.7 1.7 23.5 8.3 4.7 2.6 2.6 8.7 13.9 16.0 8.1 0.9 1.1 0.7 1.0 0.9 0.4 1.0 1.0 1.2 0.7 ACP6 "ACPL1, LPAP" ENSG00000162836 "Acid phosphatase 6, lysophosphatidic" Q9NPH0 1 147629652-147670496 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 26.6;RPTEC TERT1: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028560 Uncertain "Intracellular and membrane" 64000 "HPA028560: AB_10602427" "unprognostic (3.17e-2)" "unprognostic (3.01e-2)" "unprognostic (3.50e-1)" "unprognostic (1.87e-2)" "unprognostic (3.85e-1)" "unprognostic (8.50e-3)" "unprognostic (3.36e-3)" "unprognostic (1.00e-1)" "unprognostic (6.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (3.94e-1)" "unprognostic (8.07e-2)" "unprognostic (1.26e-1)" "prognostic favourable (6.44e-4)" 6.0 14.5 8.8 6.6 10.7 4.7 19.3 10.5 9.1 12.6 10.5 7.6 13.1 7.7 10.0 17.6 8.1 13.9 13.6 8.5 13.0 6.0 17.0 13.3 7.6 3.8 10.2 8.0 11.6 18.5 18.1 22.5 4.4 11.6 13.6 10.2 12.7 12.3 19.2 7.6 9.2 8.9 9.7 11.2 6.6 12.8 8.2 12.7 10.8 20.7 5.8 9.7 16.8 6.9 2.9 4.8 11.5 2.2 0.3 12.4 2.6 7.9 3.2 2.8 4.9 1.8 1.7 7.9 1.8 5.7 5.8 6.9 3.9 12.3 2.3 6.9 3.9 13.7 3.7 12.2 6.1 3.1 6.2 8.2 4.7 7.2 5.3 1.5 0.3 2.6 9.1 3.0 6.1 5.8 3.8 1.3 6.5 5.9 6.0 3.8 6.6 24.4 4.4 2.4 26.6 47.0 15.7 2.3 2.8 6.7 4.8 13.5 7.9 2.2 4.1 1.8 3.5 0.3 5.7 5.2 7.7 1.0 3.4 0.1 9.9 0.0 2.2 11.5 4.3 0.7 7.5 2.5 7.2 5.8 4.8 2.9 8.0 6.9 3.3 0.3 0.3 3.0 12.4 2.6 8.8 10.7 10.5 9.1 13.0 6.0 10.2 8.0 11.6 12.7 ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 15.2;lymphoid tissue: 6.1;skin 1: 14.1;tongue: 5.5" "Cell line enriched" "Detected in some" 5 "U-87 MG: 31.2" "Group enriched" "Detected in some" 5 "cervical cancer: 0.8;head and neck cancer: 2.6;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" "HPA042613: AB_10963214" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-3)" "unprognostic (1.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (4.94e-3)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" "unprognostic (1.51e-5)" "unprognostic (4.36e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-2)" "unprognostic (2.42e-1)" 0.3 0.3 1.6 0.3 5.5 0.3 1.0 15.2 5.4 0.9 0.3 4.2 0.3 0.4 0.4 1.4 1.1 0.3 0.9 0.3 2.5 1.2 0.3 0.3 0.4 0.3 6.5 0.7 0.3 0.3 0.3 0.0 0.3 5.2 1.2 0.3 0.0 0.6 0.3 0.3 14.1 0.3 0.3 4.1 0.3 0.6 0.4 5.3 0.0 0.3 5.5 6.1 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.5 0.3 3.5 0.0 0.0 0.0 0.2 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.4 0.2 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.2 0.8 0.0 0.0 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.5 15.2 5.4 2.5 1.2 6.5 0.7 5.2 5.3 ACPP "ACP-3, ACP3, PAP" ENSG00000014257 "Acid phosphatase, prostate" P15309 3 132317367-132368298 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "prostate: 345.2" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.2;NB-4: 7.7;RPMI-8226: 32.3;U-698: 9.4;U-87 MG: 9.0" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "eosinophil: 43.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" 9200 "CAB000071: , HPA004335: AB_1079684, HPA063916: " "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" 0.4 0.6 0.4 0.7 1.6 1.4 0.8 0.3 0.7 3.9 0.4 0.2 0.0 0.4 0.3 2.5 14.7 0.6 0.2 0.9 0.3 0.3 6.2 0.3 2.0 2.7 0.6 0.8 0.4 0.8 0.5 0.3 5.3 0.7 345.2 0.7 0.8 9.1 0.2 0.3 2.5 0.4 0.4 2.2 1.0 0.5 1.0 0.6 0.2 1.3 6.6 6.8 0.5 1.5 0.2 11.2 43.1 9.7 0.9 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.6 7.0 0.1 10.2 0.0 0.0 0.2 0.2 5.7 0.4 0.0 2.9 0.0 0.0 0.0 0.0 0.3 1.1 0.2 0.1 0.1 4.1 0.1 0.6 0.8 0.0 0.0 0.0 0.1 1.6 0.1 0.1 0.0 7.7 0.4 1.2 0.0 0.0 32.3 3.1 3.8 0.0 2.5 0.0 1.2 0.3 0.2 3.7 0.0 0.0 0.1 1.5 0.0 0.4 0.2 9.4 9.0 7.3 0.1 0.0 9.7 43.1 0.0 8.6 0.0 0.2 0.0 0.0 11.2 0.0 0.0 0.0 8.5 0.9 7.7 0.8 0.0 2.9 0.4 1.6 0.3 0.7 0.3 0.3 0.6 0.8 0.7 0.6 ACR ENSG00000100312 Acrosin P10323 22 50738196-50745334 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "testis: 106.3" "Cell line enhanced" "Detected in some" "Hep G2: 1.7;HUVEC TERT2: 1.1;NTERA-2: 1.7;TIME: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA048687 Enhanced "Secreted in male reproductive system" "HPA048687: " "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "unprognostic (6.27e-3)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (3.30e-3)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (1.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" 0.9 0.0 0.2 0.2 0.3 0.0 0.6 0.2 0.3 0.2 0.2 0.2 0.2 0.1 0.3 0.7 0.2 0.4 0.2 0.2 0.2 0.0 0.2 0.3 0.6 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.4 0.2 0.2 0.2 0.2 0.2 0.2 1.2 0.0 106.3 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.6 0.2 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 1.4 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.3 0.2 0.0 0.2 0.2 0.2 0.2 ACSBG1 "BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352" ENSG00000103740 "Acyl-CoA synthetase bubblegum family member 1" Q96GR2 15 78167468-78245688 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 11.4;brain: 40.5;skin 1: 19.9" "Cell line enhanced" "Detected in some" "NTERA-2: 7.9;SK-MEL-30: 3.7" "Cancer enhanced" "Detected in some" "glioma: 3.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041642, CAB045955, HPA058869" Approved Approved Vesicles Vesicles "CAB045955: AB_11124196, HPA041642: AB_2677593, HPA058869: AB_2683840" "unprognostic (1.28e-1)" "unprognostic (1.63e-2)" "unprognostic (1.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.29e-2)" "unprognostic (4.18e-2)" "unprognostic (1.32e-2)" "unprognostic (1.58e-2)" "unprognostic (1.86e-1)" "unprognostic (5.64e-2)" "unprognostic (2.02e-1)" "unprognostic (4.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (4.19e-2)" "unprognostic (1.42e-2)" 1.1 11.4 16.9 1.5 26.9 4.5 3.8 6.6 27.0 1.1 1.2 10.5 0.0 1.6 1.2 2.3 1.3 5.9 1.3 1.1 16.4 8.5 1.0 1.0 1.7 1.6 21.1 13.9 1.2 1.0 0.9 0.3 1.1 32.9 2.0 1.1 0.0 1.5 1.4 1.2 19.9 1.5 1.2 40.5 1.3 1.2 5.4 19.0 0.0 1.2 0.0 1.1 1.5 0.2 0.4 3.9 1.2 0.2 0.6 0.2 1.5 0.7 0.1 1.6 2.3 0.0 0.0 0.6 0.5 0.0 0.5 0.1 0.5 0.6 0.7 0.2 0.1 0.9 0.1 0.3 0.2 0.4 1.3 0.7 1.4 0.6 0.0 0.7 1.6 0.6 0.0 0.4 0.2 0.2 0.5 1.1 0.1 0.4 0.6 1.4 7.9 0.3 0.3 1.0 0.5 0.0 0.9 0.5 0.9 0.4 1.0 3.7 0.5 0.5 0.9 0.6 0.6 0.5 0.3 0.9 0.3 0.8 0.3 0.5 1.5 0.4 0.2 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.1 0.4 0.2 0.1 1.2 0.6 0.2 3.9 0.0 1.5 16.9 26.9 6.6 17.9 16.4 8.5 21.1 13.9 32.9 19.0 ACSBG2 "BGR, DKFZp434K1635, PRTD-NY3" ENSG00000130377 "Acyl-CoA synthetase bubblegum family member 2" Q5FVE4 19 6135247-6193094 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fatty acid metabolism, Lipid metabolism, Spermatogenesis" "Developmental protein, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "testis: 71.3" "Cell line enhanced" "Detected in some" "BEWO: 1.5;HEL: 3.4;Karpas-707: 2.6;MCF7: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043421, HPA051013" Enhanced Uncertain Cytosol Cytosol "HPA043421: AB_10794182, HPA051013: " "unprognostic (4.13e-2)" "unprognostic (1.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.27e-2)" "unprognostic (4.33e-2)" "unprognostic (1.92e-4)" "unprognostic (1.96e-2)" "unprognostic (4.17e-2)" "unprognostic (2.07e-1)" "unprognostic (2.62e-1)" "unprognostic (6.88e-3)" "unprognostic (3.13e-2)" "unprognostic (3.91e-3)" "unprognostic (2.20e-1)" "unprognostic (9.23e-2)" "unprognostic (8.78e-2)" "unprognostic (4.70e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.4 0.0 0.1 0.0 0.6 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.0 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.4 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 105.0;liver: 190.9" "Cell line enhanced" "Detected in many" "ASC diff: 147.8;ASC TERT1: 35.9;HSkMC: 78.5;RPTEC TERT1: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "neutrophil: 80.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 80.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011964" Enhanced Supported Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA011316: AB_1844536, HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favourable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 105.0 6.7 4.2 14.1 13.5 46.0 54.4 3.2 9.6 7.2 12.2 16.4 5.5 4.9 5.7 12.7 8.8 6.4 5.7 24.3 6.4 4.1 32.8 190.9 20.7 18.9 24.0 3.8 4.2 7.3 5.9 8.7 4.4 11.6 14.2 2.6 9.1 17.9 4.8 89.1 20.4 4.5 6.4 18.2 16.9 6.5 6.4 15.9 2.1 8.3 10.1 5.8 7.6 11.0 0.5 2.2 80.2 8.9 0.7 0.7 2.9 5.9 1.8 1.1 3.1 147.8 35.9 1.0 3.3 1.6 2.0 1.4 0.4 1.7 2.5 0.3 3.9 3.7 5.3 2.1 1.6 12.1 1.9 1.8 1.6 4.9 23.8 4.8 4.5 78.5 18.2 1.6 8.5 2.6 0.8 7.6 9.6 3.1 0.3 6.7 0.2 2.6 0.9 1.0 3.1 46.8 17.1 4.5 4.2 3.0 9.1 10.2 3.4 4.9 2.8 1.7 2.0 4.2 1.0 2.9 1.5 1.1 5.7 6.7 2.7 2.3 8.9 2.8 0.5 5.2 0.5 0.5 0.4 0.2 2.2 0.5 0.4 0.3 80.2 0.7 3.6 0.4 0.7 2.9 4.2 13.5 3.2 9.6 6.4 4.1 24.0 3.8 11.6 15.9 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860934-222944639 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 206.1" "Cell line enhanced" "Detected in all" "SK-MEL-30: 92.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Lipid droplets" Nucleoli "Lipid droplets" "HPA011315: AB_1848344, HPA071021: " "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavourable (2.75e-4)" "prognostic unfavourable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 14.7 17.0 22.8 9.9 26.0 16.3 51.5 19.4 45.9 15.3 16.5 16.1 11.6 12.7 10.9 18.4 28.3 9.0 11.8 22.7 20.9 22.8 17.9 22.3 15.6 10.5 19.6 21.2 11.7 10.3 206.1 8.8 19.1 24.4 44.4 16.7 14.4 34.2 15.5 19.1 11.4 12.7 12.2 22.2 9.7 28.3 13.7 14.2 13.5 17.3 11.2 8.7 14.6 15.4 15.0 22.5 21.8 16.8 16.6 20.1 16.5 9.9 17.6 27.0 29.3 11.8 29.3 7.5 12.7 33.0 15.2 32.2 15.8 25.7 4.8 7.4 12.1 29.4 5.8 28.3 19.8 8.6 11.1 11.2 14.3 17.7 26.0 7.4 5.5 15.1 40.1 25.2 44.0 16.6 21.2 18.3 21.5 21.2 14.4 8.7 13.7 9.2 7.9 22.9 8.1 21.9 40.9 14.2 10.6 7.5 20.3 92.7 10.2 18.1 11.4 10.2 16.3 8.8 9.3 6.5 3.1 16.5 11.0 6.9 30.9 16.6 14.6 21.8 20.1 16.8 19.3 11.6 12.8 14.6 15.7 15.0 18.7 16.7 21.8 16.6 15.9 22.5 9.5 16.5 22.8 26.0 19.4 45.9 20.9 22.8 19.6 21.2 24.4 14.2 ACSL4 "ACS4, FACL4, LACS4, MRX63, MRX68" ENSG00000068366 "Acyl-CoA synthetase long chain family member 4" O60488 X 109624244-109733403 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Alport syndrome, Deafness, Disease mutation, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000286, HPA005552" Supported Approved "Golgi apparatus,Mitochondria" 100000 "Golgi apparatus" Mitochondria "HPA000286: , HPA005552: AB_1078774" "unprognostic (9.13e-2)" "unprognostic (3.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (2.94e-2)" "unprognostic (5.32e-2)" "unprognostic (4.14e-3)" "unprognostic (1.92e-1)" "unprognostic (9.45e-2)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (4.78e-1)" "unprognostic (3.29e-2)" "prognostic favourable (5.73e-4)" 29.5 31.1 16.3 25.5 18.0 9.2 30.0 13.9 22.8 34.7 10.5 8.8 4.6 10.0 13.7 11.7 11.2 10.7 20.1 20.3 27.6 20.3 31.2 9.6 27.8 29.6 15.2 19.0 13.1 8.8 16.7 12.9 33.9 21.1 9.7 9.7 8.0 10.7 11.0 42.5 9.1 9.0 15.8 24.6 17.0 12.9 17.7 9.7 9.5 12.8 8.5 11.9 19.5 21.0 2.2 6.5 20.3 10.9 2.2 4.0 3.8 13.7 4.4 5.5 5.9 20.7 13.0 4.3 20.1 22.3 19.7 20.5 4.3 9.6 9.8 7.8 14.5 3.9 4.7 19.4 31.0 3.4 4.9 38.7 6.3 45.8 9.5 9.2 80.3 11.2 7.6 22.5 16.4 14.7 1.1 12.1 22.5 0.9 8.0 12.1 6.9 8.0 5.8 10.1 8.1 28.2 4.4 3.6 2.8 24.0 0.0 12.4 0.3 9.8 27.2 18.0 5.1 28.4 18.4 6.0 6.9 9.2 31.7 20.6 11.4 15.5 7.0 20.3 2.8 9.8 2.0 2.2 2.5 2.2 6.5 2.2 2.0 2.4 19.8 2.2 10.9 2.6 4.0 3.8 16.3 18.0 13.9 22.6 27.6 20.3 15.2 19.0 21.1 9.7 ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 278.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.4;RT4: 43.4;U-937: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria 22000 Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: , HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favourable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" 10.0 1.4 3.1 12.7 3.5 2.2 6.4 1.2 3.1 9.3 84.6 1.6 3.8 64.5 8.7 41.8 4.2 8.0 11.2 3.1 3.3 3.1 3.2 56.5 10.8 7.1 4.0 1.2 5.0 1.6 0.1 1.2 2.1 3.9 7.0 21.5 8.4 2.4 4.0 2.6 1.3 278.7 2.6 3.8 12.4 7.7 2.3 2.5 6.3 3.1 2.7 7.2 17.4 6.7 10.8 19.4 16.3 17.0 16.2 25.1 11.7 11.4 0.2 0.2 0.0 0.8 0.1 1.0 0.3 2.2 0.0 0.1 10.4 42.4 14.0 2.6 0.5 0.1 0.0 0.0 0.2 11.6 0.0 10.9 0.4 18.1 2.8 16.9 18.5 1.9 0.0 0.2 0.0 0.8 0.0 6.3 0.0 0.0 0.0 7.8 0.0 0.4 3.8 0.0 8.5 1.1 43.4 0.0 0.2 16.9 6.5 0.0 0.0 9.5 12.3 0.1 0.1 0.7 0.7 4.6 0.0 6.8 0.3 21.2 0.0 14.5 9.3 16.3 16.7 17.0 16.6 10.8 13.7 18.4 19.4 8.2 9.5 14.5 2.5 16.2 15.9 6.2 25.1 11.7 3.1 3.5 1.2 3.1 3.3 3.1 4.0 1.2 3.9 2.5 ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.0;ductus deferens: 30.1;seminal vesicle: 35.8;testis: 23.0" "Group enriched" "Detected in some" 5 "SCLC-21H: 14.6;U-937: 8.5" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.8;glioma: 1.9;liver cancer: 0.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA040470 Enhanced "HPA040470: AB_10794033" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (5.89e-2)" "unprognostic (6.97e-2)" "unprognostic (1.92e-2)" "unprognostic (8.38e-3)" "unprognostic (5.84e-2)" "unprognostic (8.69e-2)" "unprognostic (7.57e-2)" "unprognostic (9.28e-4)" "unprognostic (8.69e-2)" "unprognostic (3.22e-2)" "unprognostic (6.24e-3)" "unprognostic (1.79e-1)" "unprognostic (6.44e-3)" "unprognostic (1.70e-1)" 0.6 4.8 16.5 1.5 15.7 21.3 0.7 22.8 34.0 0.5 0.7 5.3 30.1 5.4 0.5 1.0 0.9 0.7 0.9 2.0 12.4 9.7 2.3 2.6 0.8 2.5 9.6 12.1 0.5 1.9 13.0 2.7 1.1 12.1 0.8 0.8 3.3 0.8 35.8 3.6 0.6 3.3 0.5 4.2 1.2 1.2 23.0 4.7 0.0 0.9 0.0 1.5 0.7 0.3 0.1 0.0 0.6 0.1 1.2 4.2 1.1 0.0 0.0 0.2 0.1 0.5 0.0 0.5 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.1 1.6 0.2 0.0 0.0 0.9 0.1 0.0 2.2 0.0 0.2 2.1 0.0 0.1 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 1.4 0.9 0.1 0.1 0.0 0.0 0.0 0.0 14.6 0.7 0.2 0.2 1.1 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.5 0.0 0.3 8.5 0.5 0.6 0.1 0.1 1.5 0.0 3.5 0.1 2.1 4.2 0.0 0.1 3.9 1.8 0.2 1.2 0.0 0.0 0.1 1.1 16.5 15.7 22.8 18.8 12.4 9.7 9.6 12.1 12.1 4.7 ACSM1 "BUCS1, MACS1" ENSG00000166743 "Acyl-CoA synthetase medium chain family member 1" Q08AH1 16 20623237-20698890 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "breast: 83.4" "Cell line enriched" "Detected in some" 5 "NTERA-2: 18.4" "Group enriched" "Detected in many" 8 "liver cancer: 14.7;prostate cancer: 36.7" "Cell type enhanced" "Detected in some" "eosinophil: 3.5;memory B-cell: 3.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA046291 Uncertain "HPA046291: AB_10960704" "unprognostic (1.08e-2)" "unprognostic (3.07e-2)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (5.49e-4)" "unprognostic (1.66e-1)" "unprognostic (3.50e-2)" "unprognostic (9.46e-2)" "unprognostic (3.10e-1)" "unprognostic (8.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.64e-1)" "unprognostic (8.24e-2)" "unprognostic (3.79e-2)" "unprognostic (3.01e-1)" "unprognostic (9.58e-2)" "unprognostic (2.33e-3)" 0.0 0.1 0.0 0.0 0.0 1.1 83.4 0.1 0.1 1.7 0.4 0.2 2.3 0.2 0.1 2.4 0.2 0.1 0.0 0.0 1.2 3.8 0.2 0.1 0.0 2.8 1.4 0.5 0.0 0.0 3.4 0.2 1.2 0.2 0.1 2.2 0.4 0.3 0.0 0.2 2.1 4.5 0.2 0.1 1.1 1.5 3.4 0.0 3.5 0.9 1.3 0.6 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.9 0.1 0.0 0.3 0.0 0.0 0.0 4.0 0.0 0.0 0.1 0.0 0.1 18.4 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.6 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 3.5 0.1 0.2 0.1 3.4 0.6 0.0 0.0 2.9 0.5 0.2 0.0 1.3 0.0 0.0 0.0 0.1 ACSM2A "A-923A4.1, ACSM2, MGC150530" ENSG00000183747 "Acyl-CoA synthetase medium chain family member 2A" Q08AH3 16 20451461-20487667 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 90 "kidney: 63.5;liver: 82.6" "Cell line enriched" "Detected in some" 5 "Hep G2: 6.4" "Group enriched" "Detected in some" 479 "liver cancer: 22.7;renal cancer: 25.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057699 Supported "HPA057699: " "unprognostic (1.17e-4)" "prognostic favourable (1.41e-5)" "unprognostic (5.25e-1)" "unprognostic (2.42e-1)" "unprognostic (9.28e-3)" "unprognostic (1.52e-1)" "unprognostic (5.10e-1)" "unprognostic (2.09e-1)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.0 63.5 82.6 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.1 0.5 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 ACSM2B "ACSM2, HXMA, HYST1046" ENSG00000066813 "Acyl-CoA synthetase medium chain family member 2B" Q68CK6 16 20536226-20576427 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "kidney: 76.1;liver: 93.4" "Cell line enhanced" "Detected in many" "AF22: 5.4;Hep G2: 9.8" "Group enriched" "Detected in some" 450 "liver cancer: 30.9;renal cancer: 17.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA057699 Supported "HPA057699: " "unprognostic (1.34e-2)" "prognostic favourable (3.31e-4)" "unprognostic (7.13e-2)" "unprognostic (2.29e-1)" "unprognostic (6.67e-2)" "unprognostic (1.24e-1)" "unprognostic (1.15e-1)" "unprognostic (2.22e-2)" 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.0 76.1 93.4 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.6 0.9 1.0 0.5 0.2 1.2 0.0 1.0 0.0 5.4 1.5 0.0 0.0 1.3 0.9 0.2 0.0 0.0 1.2 0.9 0.1 2.7 0.0 0.7 0.0 0.0 0.0 1.0 0.7 0.2 1.2 9.8 0.0 1.3 1.3 0.0 0.0 0.0 0.4 0.6 0.8 1.2 0.0 0.7 0.6 1.3 1.2 0.0 0.1 1.1 0.2 0.4 0.2 1.9 1.0 2.6 0.0 1.0 2.0 0.4 0.0 0.0 0.9 0.0 0.7 0.8 0.5 0.7 0.7 3.5 1.9 0.5 0.5 0.2 0.6 0.0 0.6 0.1 0.8 0.2 0.1 0.6 0.7 1.2 1.0 0.2 0.1 0.9 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 ACSM3 "SA, SAH" ENSG00000005187 "Acyl-CoA synthetase medium chain family member 3" Q53FZ2 16 20610243-20797581 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.6;ovary: 47.7;pancreas: 46.6" "Cell line enhanced" "Detected in some" "HEL: 19.9;HMC-1: 84.0;K-562: 59.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "eosinophil: 18.3" "Group enriched" "Detected in all" 4 "granulocytes: 18.3;T-cells: 7.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041013 Uncertain "HPA041013: AB_10671693" "unprognostic (1.62e-4)" "unprognostic (1.30e-2)" "unprognostic (2.12e-2)" "unprognostic (9.50e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.42e-2)" "unprognostic (2.20e-1)" "unprognostic (8.14e-3)" "prognostic favourable (1.97e-4)" "unprognostic (3.56e-2)" "unprognostic (1.95e-3)" "prognostic favourable (9.88e-6)" "unprognostic (1.27e-1)" "unprognostic (6.96e-2)" "unprognostic (1.06e-1)" "unprognostic (1.84e-2)" 2.1 1.8 0.3 3.7 1.0 3.4 18.6 0.4 0.4 10.9 7.0 0.5 4.3 1.7 10.4 5.3 2.9 11.2 5.0 4.0 0.3 0.3 33.1 58.6 6.4 3.7 0.4 0.3 47.7 46.6 5.1 1.0 1.8 0.7 9.6 7.2 1.4 3.6 6.5 1.0 2.0 3.1 3.2 0.5 1.3 10.9 14.7 0.3 1.5 1.5 1.6 1.8 3.9 6.6 2.2 1.9 18.3 2.9 1.9 7.4 2.3 0.2 2.7 0.5 0.1 0.8 0.5 0.3 0.0 0.2 0.0 0.2 0.2 3.9 0.3 4.4 0.0 0.3 0.0 0.4 0.3 0.9 1.4 19.9 0.0 1.5 0.2 2.2 84.0 0.8 0.4 0.1 0.3 0.0 59.1 3.3 0.0 0.3 0.1 0.7 0.1 0.7 0.6 0.0 4.2 4.0 0.2 0.1 0.1 0.0 1.1 0.0 1.3 0.1 0.3 0.2 0.2 0.2 0.1 4.8 3.7 0.2 0.2 1.5 0.1 2.3 1.6 18.3 3.3 1.0 3.8 1.4 4.1 3.0 0.2 2.2 6.5 7.4 0.5 1.9 2.9 1.9 4.6 2.3 0.3 1.0 0.4 0.4 0.3 0.3 0.4 0.3 0.7 0.3 ACSM4 ENSG00000215009 "Acyl-CoA synthetase medium chain family member 4" P0C7M7 12 7304284-7328724 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.0;testis: 3.6" "Cell line enhanced" "Detected in some" "HDLM-2: 3.8;Karpas-707: 2.5;NB-4: 3.9;SH-SY5Y: 4.6;U-87 MG: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory region: 0.6" "Low region specificity" "Detected in all" HPA049895 Uncertain "HPA049895: " "unprognostic (9.50e-5)" "unprognostic (5.45e-2)" "unprognostic (4.84e-2)" "unprognostic (6.06e-4)" "unprognostic (1.77e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-3)" "unprognostic (3.31e-3)" "unprognostic (3.85e-2)" "unprognostic (8.78e-2)" "unprognostic (3.27e-1)" "unprognostic (3.60e-1)" "unprognostic (2.45e-9)" "unprognostic (1.82e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.73e-1)" 0.2 0.5 0.1 0.7 0.1 0.0 0.1 0.1 0.6 0.1 0.1 0.9 0.1 0.0 0.1 0.1 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.0 0.1 2.0 0.1 3.6 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.3 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 3.9 0.0 0.0 0.5 0.4 0.3 0.0 0.0 0.7 4.6 0.7 1.1 0.0 0.0 1.4 1.0 0.5 0.4 0.1 0.0 0.1 0.1 0.0 6.6 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 94.6" "Group enriched" "Detected in some" 5 "ASC diff: 5.6;ASC TERT1: 12.3;HSkMC: 14.6;U-87 MG: 9.0" "Group enriched" "Detected in some" 7 "liver cancer: 20.5;renal cancer: 9.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.8;intermediate monocyte: 1.9;myeloid DC: 3.2;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 8 "dendritic cells: 3.2;monocytes: 2.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles Vesicles "HPA041435: AB_10961121" "unprognostic (1.01e-1)" "unprognostic (1.61e-3)" "unprognostic (3.73e-2)" "unprognostic (1.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-2)" "unprognostic (1.84e-2)" "unprognostic (4.64e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (2.15e-2)" "unprognostic (2.33e-1)" "unprognostic (5.11e-3)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" 11.1 1.1 1.9 0.7 2.1 0.4 3.2 1.3 1.6 1.0 1.0 2.9 0.0 0.5 0.3 2.8 0.5 0.6 1.0 0.9 3.0 1.9 8.9 94.6 0.9 1.6 2.9 2.1 0.4 1.4 0.4 0.1 0.7 2.0 0.4 0.6 0.5 0.5 0.5 4.4 0.6 0.6 0.5 2.9 1.7 0.9 1.0 3.0 0.1 1.7 0.6 0.4 0.5 0.7 0.3 3.2 0.3 2.8 0.0 0.3 0.5 0.0 0.0 0.1 0.1 5.6 12.3 0.0 0.1 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.0 14.6 0.0 0.8 0.1 0.0 0.1 0.6 1.7 0.0 0.0 0.3 0.2 0.0 0.0 0.1 2.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 9.0 0.1 0.0 0.3 2.8 0.1 0.1 1.9 0.1 0.1 0.3 0.2 3.2 0.3 0.2 0.3 0.1 0.0 1.3 0.1 0.0 0.5 1.9 2.1 1.3 1.6 3.0 1.9 2.9 2.1 2.0 3.0 ACSM6 "bA310E22.3, C10orf129" ENSG00000173124 "Acyl-CoA synthetase medium chain family member 6" Q6P461 10 95194200-95228928 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 16.3;pancreas: 7.3;stomach 1: 6.2" "Cell line enriched" "Detected in single" 30 "RT4: 9.0" "Cancer enriched" "Detected in single" 7 "urothelial cancer: 1.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" HPA044593 Uncertain "HPA044593: AB_10960261" "unprognostic (2.91e-2)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (5.73e-2)" "unprognostic (2.48e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.91e-1)" "unprognostic (3.75e-3)" "unprognostic (2.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favourable (7.71e-4)" 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.8 0.4 0.0 6.2 0.3 0.0 16.3 0.8 0.0 0.0 2.5 1.9 0.1 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACSS1 "ACAS2L, AceCS2L, dJ568C11.3, MGC33843" ENSG00000154930 "Acyl-CoA synthetase short chain family member 1" Q9NUB1 20 25006230-25058980 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 66.4" "Cell line enhanced" "Detected in many" "Hep G2: 20.5;MOLT-4: 19.8;RPMI-8226: 30.5;U-937: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041014, HPA043228" Enhanced "HPA041014: , HPA043228: " "unprognostic (6.87e-2)" "prognostic favourable (9.37e-4)" "unprognostic (5.32e-2)" "unprognostic (1.54e-1)" "unprognostic (2.78e-1)" "unprognostic (3.03e-2)" "unprognostic (3.20e-3)" "prognostic favourable (8.33e-5)" "unprognostic (2.44e-1)" "unprognostic (2.17e-2)" "unprognostic (2.43e-1)" "unprognostic (7.72e-2)" "unprognostic (4.58e-3)" "unprognostic (5.85e-2)" "unprognostic (2.68e-1)" "unprognostic (3.69e-1)" "unprognostic (1.60e-1)" 6.1 4.8 22.8 8.6 26.6 16.3 9.1 17.1 19.6 9.0 14.0 21.8 9.7 28.1 8.5 12.3 7.5 10.8 12.4 32.4 26.3 9.2 19.5 5.5 10.8 13.4 15.1 20.4 12.3 28.8 9.3 5.7 66.4 21.3 14.8 12.5 9.9 21.8 10.2 19.5 9.3 25.9 8.0 11.1 16.1 26.9 21.6 22.9 11.9 14.9 4.8 12.2 8.7 7.1 7.2 4.4 8.7 6.3 12.6 5.5 2.7 0.0 4.9 1.4 0.0 4.7 1.8 0.1 0.5 2.1 2.1 1.4 4.9 0.7 8.5 0.8 2.0 2.5 7.2 1.1 0.4 0.0 0.7 14.7 0.1 20.5 4.8 3.5 0.2 3.0 3.7 0.2 0.0 4.6 0.7 16.5 0.2 0.5 19.8 5.9 0.1 7.9 15.5 0.5 30.5 3.1 3.9 3.5 0.1 0.9 1.9 13.7 9.5 7.8 0.7 0.0 0.0 0.0 0.2 11.5 0.7 0.0 0.2 21.2 5.5 6.3 3.7 8.7 5.5 6.3 4.5 5.2 3.7 4.8 4.4 7.2 3.2 4.9 0.8 12.6 4.1 2.8 3.2 2.7 22.8 26.6 17.1 19.6 26.3 9.2 15.1 20.4 21.3 22.9 ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 63.4" "Cell line enhanced" "Detected in many" "RPMI-8226: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 17.0" "Group enriched" "Detected in many" 5 "dendritic cells: 12.6;granulocytes: 17.0;monocytes: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004141 Approved Approved Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Cytosol" Vesicles "HPA004141: AB_1078094" "unprognostic (1.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (3.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.42e-2)" "prognostic favourable (2.04e-4)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-1)" "unprognostic (2.54e-1)" 30.3 12.6 2.8 9.2 7.0 1.9 12.4 5.6 7.0 6.8 21.0 10.6 8.3 21.4 6.6 7.0 8.1 4.5 7.7 24.8 2.9 2.5 11.2 15.7 11.7 3.2 6.8 3.2 5.1 3.2 4.7 2.5 4.6 5.5 3.4 10.4 3.5 9.8 6.8 63.4 6.8 24.1 3.0 6.1 2.7 13.4 3.1 7.1 1.1 3.9 7.3 3.0 6.5 6.1 0.7 12.6 17.0 11.6 0.3 3.0 4.7 11.6 1.6 1.1 1.6 8.3 8.8 12.2 7.0 5.4 1.9 3.4 4.2 6.5 0.0 7.9 3.0 8.9 2.9 17.6 1.4 0.0 2.8 16.3 0.8 2.0 6.1 1.5 9.0 6.0 3.8 2.9 2.7 3.0 10.3 1.2 2.7 1.3 0.5 7.1 0.8 19.9 4.3 7.6 25.7 6.7 1.2 1.0 5.3 8.5 6.3 6.8 3.1 3.6 11.5 2.3 3.2 4.2 2.3 11.1 8.1 3.8 6.6 2.6 1.9 17.0 11.6 3.0 0.6 7.2 0.5 0.4 1.6 0.7 12.6 0.7 3.0 1.5 6.5 0.3 3.4 2.1 1.1 4.7 2.8 7.0 5.6 7.0 2.9 2.5 6.8 3.2 5.5 7.1 ACSS3 FLJ21963 ENSG00000111058 "Acyl-CoA synthetase short chain family member 3" Q9H6R3 12 80936414-81261205 "Enzymes, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 9.3;ASC TERT1: 10.6;Hep G2: 26.2;RH-30: 12.2;SK-BR-3: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 8.3;neutrophil: 6.0" "Lineage enriched" "Detected in single" 71 "granulocytes: 8.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039353, HPA047956, HPA061517" Approved Approved Mitochondria Mitochondria "HPA039353: AB_2676460, HPA047956: AB_2680223, HPA061517: " "unprognostic (8.59e-2)" "unprognostic (9.29e-4)" "unprognostic (1.47e-1)" "unprognostic (9.37e-3)" "unprognostic (2.46e-2)" "unprognostic (2.21e-1)" "unprognostic (9.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (7.18e-3)" "unprognostic (1.68e-1)" "unprognostic (7.79e-2)" "prognostic favourable (0.00e+0)" "unprognostic (6.16e-4)" "unprognostic (1.63e-1)" "unprognostic (2.00e-1)" "unprognostic (2.00e-4)" 19.6 18.3 7.4 1.9 8.3 1.0 8.1 2.7 7.7 13.2 2.6 5.5 10.8 1.2 18.2 14.4 2.0 8.3 8.1 10.9 6.4 3.9 24.4 37.1 8.8 1.7 7.4 6.5 16.7 2.6 21.3 11.0 4.1 6.5 7.1 1.6 10.3 20.4 11.4 9.8 2.1 1.9 6.6 5.5 2.8 1.9 4.0 4.1 0.0 9.2 2.9 1.6 3.5 6.3 0.0 0.0 8.3 0.0 0.0 0.1 0.0 0.0 0.1 2.1 0.0 9.3 10.6 0.0 1.5 6.9 1.1 1.2 0.3 0.0 0.1 0.0 3.1 0.1 0.0 0.0 0.6 0.0 1.6 0.0 0.1 26.2 3.2 0.3 0.0 7.1 0.0 0.3 0.0 0.2 0.0 0.0 4.9 0.6 0.0 0.1 3.2 0.0 0.0 12.2 1.6 0.0 0.0 2.1 0.0 0.0 11.5 0.0 5.1 0.3 0.0 1.9 1.8 0.2 0.7 0.1 0.1 0.0 2.3 0.0 2.1 8.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.1 0.0 7.4 8.3 2.7 7.7 6.4 3.9 7.4 6.5 6.5 4.1 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157875862 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Approved Nucleoli,Cytosol Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: " "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavourable (5.17e-4)" 18.9 9.2 18.0 10.0 12.7 1.6 38.7 15.3 12.2 25.2 14.4 7.4 8.4 8.9 24.8 26.8 11.0 16.6 20.5 18.8 18.7 8.6 21.7 18.9 22.5 15.1 10.4 7.9 18.5 12.3 11.3 17.0 14.2 12.3 16.8 10.5 14.3 18.1 13.6 15.6 12.8 11.5 29.2 12.3 9.2 11.8 8.8 10.9 7.5 34.0 14.6 6.9 16.1 32.5 1.4 2.4 3.8 2.6 1.9 10.0 1.6 2.1 4.2 4.9 6.4 25.0 26.1 6.9 15.1 25.2 12.1 13.0 3.3 4.7 0.0 7.0 16.4 5.9 3.5 8.2 13.1 14.5 3.0 8.6 2.5 4.8 19.8 0.6 10.2 32.6 15.6 24.9 31.8 13.2 3.1 2.4 15.3 3.7 0.1 0.2 7.4 7.7 1.4 6.6 1.8 15.8 7.9 4.4 5.4 5.8 3.3 20.7 1.7 2.3 19.0 18.5 6.1 9.1 5.7 1.6 1.2 0.1 19.0 0.5 19.9 3.8 2.6 0.2 1.1 1.7 1.2 1.4 7.8 2.5 1.8 0.8 3.1 1.5 0.8 1.9 2.3 2.4 10.0 1.6 18.0 12.7 15.3 12.2 18.7 8.6 10.4 7.9 12.3 10.9 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951667-51997078 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol Cytosol "CAB026126: , HPA063761: " "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 11.1 7.4 12.0 6.4 14.6 7.9 14.3 14.2 24.4 8.6 16.7 5.1 28.0 19.2 6.7 13.1 14.4 10.9 11.1 7.6 11.2 10.5 24.6 21.0 10.3 7.1 8.1 14.7 7.1 35.1 24.9 10.9 7.5 7.3 10.0 17.1 8.7 21.7 34.3 11.7 30.6 19.8 8.2 5.8 6.7 17.2 10.6 4.8 3.9 9.9 5.8 8.4 10.1 12.1 0.5 1.3 6.8 4.0 0.1 1.6 0.6 6.2 13.8 10.7 5.9 12.3 9.7 6.1 7.1 8.1 7.6 5.8 27.8 9.7 2.7 10.0 7.7 11.1 10.2 8.6 7.9 4.0 12.0 6.8 3.5 8.6 14.1 10.9 25.5 18.9 11.2 8.6 10.9 10.7 7.2 8.6 6.7 12.8 10.4 9.5 10.4 4.8 5.6 8.3 3.5 21.5 9.6 13.7 11.4 7.7 11.0 5.0 12.1 7.1 6.7 5.2 8.0 5.9 3.4 5.2 3.7 3.8 5.6 5.3 6.7 4.5 2.2 6.8 0.7 3.3 1.0 0.1 0.6 0.7 1.3 0.5 1.6 0.9 1.9 0.1 4.0 0.7 1.0 0.6 12.0 14.6 14.2 24.4 11.2 10.5 8.1 14.7 7.3 4.8 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157629005 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.2;breast: 15.3" "Group enriched" "Detected in some" 4 "ASC diff: 15.1;HDLM-2: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.8" "Lineage enriched" "Detected in single" 4 "T-cells: 2.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basal ganglia: 29.2;cerebral cortex: 8.1;hippocampal formation: 21.6" "HPA007982, HPA011933" Approved "Intracellular and membrane" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 36.2 3.7 3.9 2.7 10.3 0.7 15.3 1.6 4.4 0.9 9.4 2.7 0.0 5.5 0.7 1.0 0.8 0.8 1.8 1.0 9.2 3.1 1.1 3.3 0.8 1.2 3.7 3.1 5.1 2.4 0.5 12.0 0.7 3.5 0.9 4.4 0.0 1.5 1.0 1.3 0.7 4.4 0.8 2.8 0.8 3.4 1.1 4.0 0.0 0.9 0.5 1.0 0.6 2.9 0.6 0.0 0.0 0.0 0.0 2.8 0.4 2.0 0.0 0.0 0.1 15.1 0.4 0.3 0.4 0.4 0.1 0.5 2.2 0.2 0.0 0.2 1.2 0.0 0.1 0.0 0.3 6.6 1.0 0.0 0.0 0.5 0.0 0.0 1.1 0.1 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.0 1.3 0.7 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.3 0.0 0.8 0.2 0.0 0.2 0.8 2.4 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.5 0.0 1.0 0.6 1.8 1.2 0.0 0.5 2.8 1.1 0.0 0.0 0.0 0.0 0.0 0.4 3.9 10.3 1.6 4.4 9.2 3.1 3.7 3.1 3.5 4.0 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 20.5;RH-30: 17.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favourable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 12.0 6.0 13.6 8.2 9.9 3.8 10.7 14.5 14.2 10.2 14.1 4.7 9.7 10.4 9.3 9.9 13.6 7.6 17.7 5.6 10.0 9.0 9.0 10.3 7.5 4.7 5.9 10.6 7.6 9.8 8.6 15.9 10.6 7.3 12.2 9.1 7.6 12.2 12.0 19.6 29.5 17.8 13.8 5.4 6.5 9.3 11.0 6.4 1.5 9.5 6.9 6.8 13.5 11.8 0.7 3.0 0.5 3.6 7.7 4.6 1.4 1.3 1.5 9.8 3.6 5.8 3.7 4.0 3.0 3.6 5.2 9.1 4.2 5.9 0.0 2.7 4.8 4.6 8.9 4.4 6.7 1.0 5.4 0.6 2.7 7.3 20.5 0.6 0.7 6.2 5.6 3.3 6.7 3.9 1.4 2.5 3.5 3.4 0.3 0.5 11.0 2.6 0.1 17.1 0.9 4.2 8.3 9.7 5.5 2.5 3.1 3.7 1.9 1.0 3.0 4.8 5.7 4.5 2.1 0.7 0.2 1.8 3.0 0.3 3.8 0.4 3.0 0.5 1.2 3.6 0.5 0.3 4.6 2.1 2.3 0.7 3.0 0.7 0.1 7.7 3.1 3.0 0.4 1.4 13.6 9.9 14.5 14.2 10.0 9.0 5.9 10.6 7.3 6.4 ACVR2B ActR-IIB ENSG00000114739 "Activin A receptor type 2B" Q13705 3 38453851-38493142 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 16.6;NTERA-2: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007398, CAB025115, HPA040384" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Nucleoplasm, Cytosol" "Nuclear bodies" "CAB025115: , HPA007398: , HPA040384: " "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.47e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.32e-2)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "unprognostic (1.83e-1)" "unprognostic (4.75e-1)" 2.8 7.4 5.5 4.6 7.9 1.1 5.5 13.2 7.5 5.2 3.4 7.2 4.5 2.8 4.7 5.1 2.5 5.6 3.3 3.9 5.9 5.4 5.3 5.4 6.9 2.2 5.9 5.4 8.3 6.1 11.3 5.1 16.0 6.5 3.9 3.6 5.0 4.6 4.2 15.9 2.4 2.8 4.6 4.7 3.1 4.0 9.1 9.1 12.8 4.8 1.7 2.2 4.2 10.3 0.3 0.3 0.5 0.2 0.5 1.6 0.3 0.8 1.4 16.6 1.4 0.6 0.4 8.9 0.3 0.5 0.3 0.7 2.4 1.1 0.1 1.3 0.4 1.0 6.3 1.0 0.9 2.4 4.1 4.2 2.6 3.5 0.8 3.0 1.6 0.7 0.9 0.5 1.8 1.1 7.0 1.4 0.3 1.3 5.1 1.9 20.5 0.7 1.7 5.5 1.0 1.1 2.0 3.9 6.8 0.5 2.5 2.2 1.4 4.0 0.9 0.6 2.7 0.4 1.4 4.0 5.4 0.9 0.6 2.5 1.1 0.5 0.1 0.1 0.4 0.2 0.6 0.2 1.0 0.5 0.0 0.3 1.6 1.5 0.3 0.5 0.2 0.3 0.7 0.3 5.5 7.9 13.2 7.0 5.9 5.4 5.9 5.4 6.5 9.1 ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 55.0" "Cell line enhanced" "Detected in some" "ASC diff: 18.1;ASC TERT1: 12.4;EFO-21: 16.0;HUVEC TERT2: 58.5;TIME: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "classical monocyte: 3.6;myeloid DC: 5.0" "Group enriched" "Detected in many" 12 "dendritic cells: 5.0;monocytes: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" 25.5 5.1 3.2 9.3 4.3 0.2 15.6 1.6 3.6 15.1 20.1 3.7 13.1 4.9 12.7 11.0 12.1 13.9 11.0 15.4 3.7 3.2 13.6 3.4 55.0 19.1 4.9 3.6 5.9 6.1 21.6 2.7 44.1 5.3 12.3 14.7 12.3 6.9 10.6 14.2 8.0 11.1 8.2 3.7 14.8 8.1 3.5 3.6 1.7 12.9 6.8 5.4 9.3 11.2 0.1 5.0 0.3 3.6 0.0 0.1 0.7 0.0 0.2 0.1 0.0 18.1 12.4 0.0 0.8 1.6 0.0 0.0 0.1 0.1 0.0 16.0 6.8 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 2.7 0.0 0.4 5.0 0.0 0.1 0.0 58.5 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 45.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 3.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.7 3.2 4.3 1.6 3.6 3.7 3.2 4.9 3.6 5.3 3.6 ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983278-51989202 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "intestine: 53.3;kidney: 91.6;liver: 77.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB003695, HPA036174, HPA036175" Enhanced 28000000 "CAB003695: AB_425286, HPA036174: , HPA036175: " "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-3)" "unprognostic (3.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.08e-2)" "unprognostic (2.36e-2)" "unprognostic (2.70e-2)" "prognostic favourable (2.93e-4)" "unprognostic (3.57e-1)" "unprognostic (3.75e-1)" "unprognostic (7.88e-2)" "prognostic favourable (6.77e-4)" 4.4 8.5 2.5 3.9 3.0 1.5 4.4 1.5 3.3 3.2 24.9 4.1 9.8 34.5 1.9 7.9 3.8 3.0 8.4 4.1 2.3 1.8 91.6 77.8 3.5 6.3 2.8 2.9 2.1 9.0 6.2 1.9 4.3 2.9 3.7 6.2 6.6 9.4 9.2 7.6 2.6 53.3 2.1 3.5 3.4 4.9 1.5 1.7 0.6 5.9 6.7 4.1 3.3 2.5 5.0 12.1 3.8 10.0 12.1 6.4 4.5 3.9 8.0 3.9 10.9 9.0 12.2 12.9 4.2 7.9 9.3 5.1 12.5 20.9 2.5 3.6 7.3 4.9 4.0 25.7 3.7 7.0 5.1 9.0 4.6 38.5 16.7 6.0 5.8 14.0 21.3 8.2 22.2 3.5 13.5 8.0 9.1 11.2 0.0 11.0 5.7 13.6 3.1 3.3 22.6 24.4 15.1 5.5 5.0 5.3 17.6 9.3 14.2 7.9 1.7 6.7 6.4 8.3 5.0 21.0 4.9 3.8 7.9 12.6 8.1 3.8 10.0 0.2 6.4 9.0 3.6 5.0 2.0 2.8 12.1 4.0 3.3 4.0 0.0 12.1 3.4 1.9 2.7 4.5 2.5 3.0 1.5 3.3 2.3 1.8 2.8 2.9 2.9 1.7 ACY3 "ACY-3, HCBP1, MGC9740" ENSG00000132744 "Aminoacylase 3" Q96HD9 11 67642555-67650659 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 72.2;kidney: 28.9" "Cell line enhanced" "Detected in some" "CACO-2: 6.0;CAPAN-2: 9.4;Daudi: 34.2;RPMI-8226: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 21.1" "Group enriched" "Detected in many" 6 "dendritic cells: 5.9;monocytes: 21.1" "Low region specificity" "Detected in all" "HPA039219, HPA048187" Enhanced "HPA039219: AB_10671872, HPA048187: AB_2680306" "unprognostic (8.37e-3)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "prognostic favourable (4.80e-4)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (1.38e-2)" "unprognostic (1.43e-1)" "unprognostic (7.37e-4)" "unprognostic (2.44e-3)" "unprognostic (1.15e-1)" "unprognostic (3.21e-1)" "unprognostic (2.63e-3)" "unprognostic (1.07e-1)" "unprognostic (8.24e-2)" "unprognostic (2.68e-2)" "unprognostic (1.48e-3)" 0.1 0.1 3.4 1.8 5.5 0.6 0.5 0.8 7.8 5.5 13.0 15.3 0.2 38.2 0.3 2.1 0.7 0.4 6.1 0.1 3.1 2.9 28.9 18.3 0.2 3.1 4.6 5.1 0.1 11.2 0.0 0.3 0.1 7.1 0.4 2.2 0.3 1.2 0.2 0.1 0.1 72.2 0.1 5.2 0.9 5.9 0.1 2.8 0.7 0.2 0.0 4.2 0.2 0.2 1.1 5.9 0.0 21.1 2.3 0.9 1.2 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 9.4 34.2 0.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 3.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 1.5 0.0 0.0 1.1 0.0 5.9 0.0 0.0 0.0 0.1 0.2 0.8 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.8 0.3 0.0 0.5 0.0 0.1 4.9 0.5 1.0 0.2 0.1 2.6 1.1 0.9 0.6 0.0 2.3 21.1 5.9 0.0 1.2 3.4 5.5 0.8 7.8 3.1 2.9 4.6 5.1 7.1 2.8 ACYP1 ENSG00000119640 "Acylphosphatase 1" P07311 14 75053221-75069483 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034944 Approved Approved Nucleoplasm,Cytosol 92000 Cytosol Nucleoplasm "HPA034944: AB_10669898" "prognostic favourable (1.17e-4)" "unprognostic (3.83e-3)" "unprognostic (1.92e-1)" "unprognostic (5.90e-2)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "prognostic unfavourable (6.14e-7)" "unprognostic (5.48e-2)" "unprognostic (4.40e-1)" "unprognostic (1.64e-2)" "unprognostic (1.37e-3)" "unprognostic (3.56e-2)" "unprognostic (4.74e-2)" "unprognostic (6.69e-3)" "unprognostic (9.39e-2)" "unprognostic (1.07e-1)" "unprognostic (5.32e-3)" 8.7 27.4 23.0 13.9 20.4 12.7 16.2 24.0 25.2 10.6 14.9 14.8 14.3 11.3 10.2 26.9 11.6 21.4 7.1 10.8 19.9 30.2 12.2 5.2 10.9 17.6 28.7 19.3 9.1 7.0 8.9 38.2 10.4 24.4 10.0 19.8 9.4 9.7 12.9 22.3 24.4 11.3 11.4 27.5 10.9 14.0 16.7 22.9 8.3 20.2 10.3 19.0 7.5 12.0 10.6 7.6 12.3 6.6 10.0 17.8 5.1 24.6 13.6 19.6 12.0 8.0 9.3 10.9 14.2 5.5 14.4 20.6 13.7 27.8 27.3 8.7 5.9 22.3 12.9 6.3 23.7 39.6 15.9 17.7 35.8 9.7 4.7 11.1 18.5 5.1 9.1 20.0 10.3 19.0 13.9 33.0 19.0 16.9 24.9 20.8 6.0 13.7 20.0 25.9 12.7 20.4 13.1 36.0 14.6 9.7 6.6 22.0 14.7 11.0 8.9 9.9 18.4 19.9 15.2 7.9 15.9 28.6 15.1 13.1 10.6 3.9 2.2 12.3 8.6 4.3 9.7 10.0 14.5 9.9 3.8 10.6 12.2 11.3 0.9 10.0 6.6 7.6 17.8 5.1 23.0 20.4 24.0 25.2 19.9 30.2 28.7 19.3 24.4 22.9 ACYP2 ENSG00000170634 "Acylphosphatase 2" P14621 2 53970838-54305300 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 116.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035301 Uncertain Approved Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA035301: AB_10670291" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (6.90e-3)" "unprognostic (6.21e-2)" "unprognostic (2.03e-3)" "unprognostic (3.17e-1)" "unprognostic (5.22e-2)" "unprognostic (7.83e-3)" "unprognostic (3.64e-3)" "unprognostic (1.16e-1)" "unprognostic (6.66e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" "unprognostic (2.24e-2)" 12.9 24.0 31.0 4.6 33.9 5.6 10.1 15.5 29.3 6.7 6.2 19.4 4.4 6.2 6.7 10.5 6.6 7.1 7.3 39.6 29.1 28.4 8.8 18.7 7.2 7.5 35.7 18.2 5.7 10.3 9.1 9.7 5.9 28.1 10.4 4.8 6.3 11.5 8.4 116.4 6.6 5.6 6.9 35.7 7.8 7.5 6.5 22.7 3.5 8.2 22.9 6.4 8.2 4.1 20.9 23.7 24.1 10.2 12.6 15.9 8.9 7.6 4.3 4.5 3.7 16.6 13.1 4.1 9.2 6.9 5.7 5.0 1.0 5.6 14.9 24.4 9.1 6.6 2.4 7.7 5.3 12.9 10.2 11.5 4.6 11.4 6.8 9.6 5.6 9.5 14.5 4.1 6.8 2.6 4.7 8.0 12.1 4.9 5.9 11.9 5.2 5.3 4.7 4.3 8.4 13.5 7.0 13.2 8.7 11.1 7.0 4.1 2.6 8.8 9.2 8.1 7.8 3.5 8.5 16.9 9.3 8.3 11.7 16.4 8.9 24.1 10.2 19.8 13.4 9.0 11.9 20.9 13.4 12.7 14.7 19.7 15.9 13.4 8.5 12.6 8.8 23.7 11.6 8.9 31.0 33.9 15.5 29.3 29.1 28.4 35.7 18.2 28.1 22.7 ADA ENSG00000196839 "Adenosine deaminase" P00813 20 44619522-44652233 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease mutation, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 64.0;intestine: 142.2;lymphoid tissue: 99.0" "Cell line enriched" "Detected in many" 8 "MOLT-4: 197.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 64.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001399, CAB004307, HPA023884" Enhanced Supported "Plasma membrane,Cytosol" 650000 "Plasma membrane" Cytosol "CAB004307: AB_626634, HPA001399: AB_1078099, HPA023884: AB_1844573" "unprognostic (4.30e-2)" "unprognostic (6.89e-2)" "unprognostic (3.96e-2)" "prognostic unfavourable (1.23e-7)" "unprognostic (9.33e-2)" "unprognostic (9.07e-3)" "prognostic unfavourable (6.77e-5)" "prognostic unfavourable (2.20e-4)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-1)" "prognostic unfavourable (2.94e-14)" "unprognostic (2.29e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" 8.1 3.2 2.5 5.4 6.5 5.3 5.1 0.9 5.0 2.8 7.4 5.0 1.8 142.2 1.7 3.4 4.6 2.4 3.0 9.2 2.7 0.8 1.3 2.1 2.8 8.9 3.6 2.3 1.2 2.4 0.8 0.3 1.8 3.9 1.8 1.5 0.7 2.6 1.3 2.0 2.8 5.0 2.1 1.3 9.5 19.7 1.6 6.1 99.0 2.8 2.1 7.6 3.6 2.6 1.3 41.6 0.5 64.0 16.9 10.3 9.6 1.4 3.9 2.0 1.3 3.9 5.4 3.3 1.4 0.8 1.4 1.0 1.8 1.5 4.0 1.7 1.8 0.2 1.4 5.8 0.8 0.3 1.8 0.8 0.7 1.4 1.6 0.6 2.1 26.1 2.5 0.5 0.9 5.4 2.0 3.3 0.6 3.4 197.1 2.9 0.5 1.4 10.6 2.8 9.8 0.2 0.0 0.0 0.9 2.1 0.4 2.5 0.4 1.9 1.7 1.0 2.0 2.2 0.2 4.3 2.7 8.3 0.3 3.3 0.9 0.0 1.8 0.2 8.7 30.7 5.7 1.3 7.3 10.3 6.8 1.0 5.7 8.1 0.5 16.9 64.0 41.6 5.3 9.6 2.5 6.5 0.9 5.0 2.7 0.8 3.6 2.3 3.9 6.1 ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17221989 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 63.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.0;EFO-21: 11.5;HUVEC TERT2: 12.4;Karpas-707: 22.1;MOLT-4: 20.5;U-266/70: 12.6;U-937: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" 50000000 "HPA007888: AB_1078495" "unprognostic (1.03e-3)" "unprognostic (2.00e-3)" "unprognostic (6.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (4.48e-2)" "unprognostic (3.09e-3)" "unprognostic (3.80e-2)" "prognostic favourable (9.26e-4)" "prognostic favourable (8.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (4.86e-3)" "unprognostic (1.96e-2)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" 24.7 6.6 6.9 15.3 7.5 8.7 6.3 9.7 9.2 7.8 9.8 17.3 3.9 7.0 9.6 7.0 6.9 18.2 12.4 15.9 6.4 8.8 15.2 8.5 28.6 24.3 9.2 5.8 8.9 6.7 0.6 13.7 8.4 14.5 7.4 12.3 15.3 6.9 6.3 2.5 2.5 12.6 7.9 18.2 45.0 7.2 9.7 5.3 63.0 7.5 2.9 22.6 18.0 4.1 6.1 29.8 2.6 46.4 9.5 7.9 28.3 0.0 0.0 3.4 0.0 0.0 0.6 0.1 1.2 0.1 0.0 0.0 0.0 13.0 2.9 11.5 3.6 0.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.2 0.1 6.2 0.0 0.1 0.0 12.4 0.1 22.1 0.5 0.0 20.5 1.5 10.2 0.0 0.4 0.0 3.2 0.0 3.9 5.8 0.1 0.0 0.1 0.0 0.0 5.8 1.4 0.0 0.1 0.1 0.0 12.6 1.1 0.7 0.1 20.7 0.1 2.6 44.1 2.4 7.9 46.4 6.3 6.1 6.4 7.9 29.8 5.0 7.6 7.8 2.1 9.5 35.2 14.7 3.6 28.3 6.9 7.5 9.7 9.2 6.4 8.8 9.2 5.8 14.5 5.3 ADAM10 "CD156c, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588807-58749978 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" 8200000 "Plasma membrane" "Nucleoplasm, Vesicles" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavourable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 25.9 11.1 15.5 17.1 17.7 15.6 20.0 25.2 17.6 18.6 20.1 15.7 12.7 13.9 19.9 11.8 17.1 13.8 18.0 18.8 17.6 13.7 20.8 14.8 25.0 26.1 23.1 12.4 13.9 13.1 10.9 11.6 36.1 14.5 23.6 16.7 14.6 12.4 19.1 8.9 15.4 15.6 12.8 30.4 40.4 18.4 8.5 18.9 38.5 27.3 9.2 14.9 30.0 19.1 6.2 12.7 26.9 23.7 9.8 12.2 12.8 11.8 26.9 7.3 8.0 9.4 13.6 18.5 10.2 30.4 7.5 10.5 12.4 15.7 5.5 31.6 9.1 24.3 4.4 10.8 10.0 8.2 5.6 9.4 9.8 11.5 10.5 6.6 27.2 11.9 8.0 5.2 7.7 14.6 5.9 15.0 13.2 4.4 21.9 7.6 10.0 3.8 9.1 24.0 14.1 17.5 32.1 8.0 5.2 11.1 12.9 17.6 7.7 13.3 10.3 9.9 11.0 76.0 9.8 8.4 18.1 6.0 13.8 12.9 17.3 12.9 18.8 10.4 8.1 21.5 12.2 5.3 8.0 7.1 12.7 6.2 8.4 7.0 26.9 9.8 23.7 5.8 10.3 12.8 15.5 17.7 25.2 16.9 17.6 13.7 23.1 12.4 14.5 18.9 ADAM17 "CD156B, cSVP, TACE" ENSG00000151694 "ADAM metallopeptidase domain 17" P78536 2 9488486-9555792 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010738, CAB025906, HPA051575" Approved Supported Cytosol "Intracellular and membrane" 27000 Cytosol "CAB025906: , HPA010738: AB_1078100, HPA051575: " "unprognostic (2.28e-1)" "unprognostic (1.29e-3)" "unprognostic (1.28e-1)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (5.15e-2)" "unprognostic (2.12e-3)" "unprognostic (1.55e-1)" "unprognostic (4.09e-2)" "unprognostic (3.69e-1)" "unprognostic (3.53e-3)" "unprognostic (3.13e-1)" "unprognostic (3.82e-3)" "unprognostic (8.63e-2)" "unprognostic (2.61e-1)" "unprognostic (4.48e-2)" "prognostic unfavourable (4.23e-5)" 18.6 11.0 13.6 15.4 13.8 21.9 14.7 20.4 15.5 14.0 11.7 13.8 8.3 8.7 14.2 15.8 18.7 10.7 17.4 13.4 11.2 12.4 12.4 7.8 24.7 15.0 11.6 11.7 18.1 9.6 10.9 11.9 29.0 11.2 8.2 9.4 10.6 12.5 9.8 12.3 16.7 11.1 13.9 14.3 21.4 8.9 17.4 12.3 14.7 12.5 13.9 20.3 12.3 14.4 7.0 7.7 16.0 10.2 6.0 7.9 6.0 7.7 12.7 13.4 13.9 26.5 19.8 24.2 8.1 13.8 9.4 13.9 11.2 18.7 22.1 11.8 10.2 14.2 9.9 17.2 12.9 8.8 9.9 11.3 9.6 9.9 37.5 11.0 12.7 22.1 17.4 15.0 29.1 23.5 15.3 8.5 10.0 7.3 8.3 11.1 11.1 5.2 9.6 13.2 10.5 12.5 12.9 7.9 19.8 9.1 11.1 19.3 5.7 14.2 18.8 16.7 8.7 11.7 15.4 11.1 10.0 19.2 13.8 7.1 19.8 16.0 9.8 7.6 6.1 10.2 7.9 7.0 5.0 5.1 7.7 5.1 4.5 4.6 11.8 6.0 9.5 4.3 5.7 6.0 13.6 13.8 20.4 13.1 11.2 12.4 11.6 11.7 11.2 12.3 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 53.7" "Cell line enhanced" "Detected in many" "SH-SY5Y: 6.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4 "basophil: 2.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" 1301000000 38000000 Vesicles "HPA042014: , HPA042844: , HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 1.4 1.0 3.1 1.4 3.7 0.5 1.4 6.6 4.2 1.4 1.4 1.4 1.4 4.1 1.6 4.0 1.4 2.1 1.5 1.7 3.4 2.2 1.8 53.7 4.8 1.4 2.1 1.4 2.3 1.8 2.2 4.2 1.7 1.6 1.6 1.1 1.6 2.5 2.0 2.6 2.9 4.4 1.4 2.0 1.4 5.5 3.8 1.4 1.4 1.7 1.4 1.4 1.7 1.4 0.3 0.0 2.3 0.0 0.0 0.5 0.1 0.0 1.4 3.4 4.7 2.7 2.5 1.2 1.1 0.9 0.5 0.7 0.5 3.7 0.4 1.5 0.8 0.6 0.3 0.6 0.1 2.0 3.1 0.4 1.4 0.7 2.0 0.1 1.1 6.6 1.7 0.5 1.3 0.3 0.1 1.4 0.5 5.6 0.1 1.5 3.6 2.0 0.4 0.4 1.6 1.5 1.4 2.2 6.9 2.4 1.3 1.8 5.9 0.6 0.8 2.5 1.4 1.6 0.0 2.5 0.6 0.5 2.1 0.4 2.8 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.1 3.7 6.6 4.2 3.4 2.2 2.1 1.4 1.6 1.4 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110851-179345430 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 13.7;ASC TERT1: 13.7;BJ: 12.1;fHDF/TERT166: 14.2;HHSteC: 44.5;HSkMC: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavourable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 24.2 4.3 0.9 5.8 0.7 0.7 29.1 0.9 2.3 16.3 10.1 0.4 3.9 2.7 12.0 9.5 6.0 7.2 9.5 10.1 0.7 1.2 4.2 7.4 13.1 25.9 1.0 1.3 6.3 2.7 1.0 8.7 15.1 2.4 6.0 2.6 3.8 2.5 3.8 3.8 4.6 4.6 13.8 0.7 16.5 4.2 4.3 0.5 0.8 3.2 5.9 1.2 8.8 14.7 1.4 1.3 2.1 0.3 0.8 0.6 0.1 0.0 0.0 0.0 0.3 13.7 13.7 0.0 12.1 2.0 4.6 4.9 0.0 0.0 0.0 0.1 14.2 0.0 0.7 0.0 2.0 0.0 0.6 0.0 0.0 0.9 44.5 0.0 0.0 35.5 0.0 1.2 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.5 0.0 0.0 0.1 0.0 3.9 0.0 7.7 1.2 10.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 1.5 0.3 0.4 0.6 0.2 0.3 0.6 0.5 0.4 1.3 1.4 0.5 0.5 2.1 0.8 0.1 0.8 0.5 0.1 0.9 0.7 0.9 2.3 0.7 1.2 1.0 1.3 2.4 0.5 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184308-161199056 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 58.0" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 10.7;HUVEC TERT2: 12.9;SH-SY5Y: 7.2;TIME: 10.8;U-251 MG: 9.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basal ganglia: 20.7;cerebral cortex: 10.0;midbrain: 28.6;pons and medulla: 20.5;thalamus: 15.7" "Cell type enriched" "Detected in some" 8 "plasmacytoid DC: 8.0" "Lineage enriched" "Detected in many" 8 "dendritic cells: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" "Nuclear speckles" "CAB025876: , HPA051296: , HPA068374: " "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavourable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavourable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 58.0 9.7 2.6 18.1 20.7 1.8 14.6 1.5 10.7 7.8 6.3 33.4 0.0 1.9 5.8 2.0 7.7 14.2 16.4 19.5 3.4 2.3 3.1 11.0 15.7 2.7 28.6 3.5 35.7 10.6 4.7 4.9 4.4 20.5 5.8 3.4 0.0 1.7 1.7 7.7 1.7 3.0 12.0 15.5 1.9 8.1 1.7 15.7 0.0 7.5 1.2 1.4 8.7 4.0 0.5 8.0 1.0 0.2 0.4 0.6 0.2 0.0 0.0 0.2 0.1 6.0 3.8 0.5 4.8 0.2 0.4 2.8 0.1 0.1 0.2 4.1 1.5 0.1 0.0 0.0 1.7 0.1 0.3 0.1 0.4 1.2 0.6 0.0 0.1 4.2 0.0 10.7 0.1 12.9 0.1 0.3 0.3 0.1 0.0 0.2 4.8 0.0 0.1 4.7 0.1 0.0 0.1 0.1 7.2 0.0 0.1 0.1 0.2 0.5 10.8 6.8 0.1 0.3 9.6 0.2 0.1 0.1 2.1 0.1 0.1 0.7 0.2 0.2 0.6 0.1 0.3 0.3 0.3 0.3 0.1 0.5 0.4 0.4 1.0 0.4 0.1 8.0 0.3 0.2 2.6 20.7 1.5 10.0 3.4 2.3 28.6 3.5 20.5 15.7 ADAR "ADAR1, G1P1, IFI4" ENSG00000160710 "Adenosine deaminase, RNA specific" P55265 1 154582062-154627999 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing, RNA-mediated gene silencing" "DNA-binding, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003890, HPA051519, CAB056157" Enhanced Enhanced Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "CAB056157: , HPA003890: AB_1078103, HPA051519: AB_2681520" "unprognostic (3.46e-1)" "unprognostic (8.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.83e-2)" "unprognostic (2.38e-1)" "unprognostic (9.37e-2)" "unprognostic (2.07e-2)" "unprognostic (6.97e-2)" "unprognostic (2.03e-1)" "unprognostic (2.90e-1)" "unprognostic (4.13e-2)" "unprognostic (7.16e-2)" "prognostic unfavourable (7.30e-5)" "unprognostic (3.44e-1)" "unprognostic (1.49e-1)" "unprognostic (9.00e-2)" "unprognostic (3.94e-2)" 36.1 33.1 30.3 36.6 44.4 43.1 29.7 41.4 50.8 30.7 28.2 33.3 19.9 31.4 38.0 26.5 27.7 32.9 28.9 24.0 25.7 38.1 31.5 36.0 34.7 41.3 27.3 32.6 39.2 29.5 46.2 38.4 33.9 39.8 28.8 31.1 32.2 36.7 30.2 14.0 27.0 40.6 36.3 24.4 47.7 29.1 21.9 26.9 57.6 32.8 16.7 41.9 29.7 27.6 7.8 6.1 25.1 8.6 6.4 9.7 5.6 26.1 30.3 26.0 32.0 26.3 27.3 31.0 18.0 36.3 60.5 52.6 26.1 25.8 47.2 29.2 28.8 25.5 33.2 34.3 30.8 45.8 16.7 24.6 21.5 14.8 28.7 34.7 27.3 26.5 25.1 31.0 31.8 31.0 23.2 36.3 21.1 32.0 41.9 17.9 43.0 22.9 40.1 21.4 37.9 20.8 29.2 25.9 30.9 31.2 50.4 37.0 33.9 42.7 28.2 21.8 21.4 17.9 20.9 43.1 47.1 50.7 21.1 22.9 24.5 6.9 6.6 12.0 9.4 8.3 8.8 7.8 9.4 9.7 6.1 6.2 8.8 8.6 25.1 6.4 8.6 5.5 7.1 5.6 30.3 44.4 41.4 50.8 25.7 38.1 27.3 32.6 39.8 26.9 ADARB1 "ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1" ENSG00000197381 "Adenosine deaminase, RNA specific B1" P78563 21 45073853-45226560 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 59.9" "Cell line enhanced" "Detected in many" "HeLa: 27.3;HHSteC: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029645 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA029645: AB_10602106" "unprognostic (2.69e-1)" "unprognostic (7.65e-2)" "prognostic unfavourable (8.16e-5)" "unprognostic (1.82e-2)" "unprognostic (1.07e-2)" "unprognostic (9.07e-2)" "unprognostic (3.29e-2)" "unprognostic (6.97e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-2)" "unprognostic (1.28e-1)" "unprognostic (3.44e-1)" "prognostic unfavourable (3.56e-4)" "unprognostic (4.57e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-2)" "unprognostic (2.38e-2)" 12.2 5.3 7.1 10.4 8.4 4.5 8.9 33.1 11.6 11.7 17.2 2.5 5.6 2.9 13.4 6.6 14.0 8.8 11.1 6.7 7.3 8.1 4.6 4.0 19.9 11.8 7.4 8.1 5.3 4.7 19.0 3.7 12.0 13.6 14.7 5.0 11.0 4.6 8.7 11.8 10.8 5.9 59.9 3.5 10.5 11.7 3.8 4.0 3.9 3.8 4.5 8.4 34.6 20.3 6.1 2.1 4.8 0.6 0.5 2.6 0.5 3.1 0.4 2.4 2.9 3.0 2.1 3.3 2.1 3.5 6.7 4.3 4.9 0.5 1.0 5.7 10.3 0.3 3.6 8.7 7.5 0.7 3.2 6.8 27.3 3.2 31.7 4.6 3.3 11.3 3.8 2.4 7.1 7.1 1.5 0.4 19.6 2.3 3.0 4.4 4.0 4.7 0.9 2.3 3.1 1.5 1.0 14.4 3.8 16.7 0.7 5.3 1.6 3.7 7.4 2.2 2.7 9.0 7.8 3.1 1.4 0.8 2.0 10.9 11.9 1.3 0.2 4.8 1.1 0.6 1.8 2.4 2.6 1.6 0.0 6.1 1.8 1.4 0.2 0.5 0.3 2.1 1.6 0.5 7.1 8.4 33.1 11.6 7.3 8.1 7.4 8.1 13.6 4.0 ADAT1 ENSG00000065457 "Adenosine deaminase, tRNA specific 1" Q9BUB4 16 75596981-75623300 "Enzymes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040713, HPA040903" Approved Supported Nucleoplasm Nucleoplasm "HPA040713: AB_10795371, HPA040903: AB_10794071" "unprognostic (7.71e-3)" "unprognostic (5.35e-2)" "unprognostic (7.62e-2)" "unprognostic (9.00e-2)" "unprognostic (9.99e-2)" "unprognostic (4.69e-2)" "unprognostic (4.54e-2)" "unprognostic (6.65e-3)" "unprognostic (3.38e-1)" "unprognostic (1.14e-2)" "unprognostic (9.75e-2)" "unprognostic (2.97e-1)" "unprognostic (4.60e-3)" "unprognostic (7.21e-2)" "unprognostic (4.92e-1)" "unprognostic (5.58e-3)" "unprognostic (8.27e-2)" 14.8 17.1 12.5 12.6 18.2 13.0 15.1 11.0 23.3 13.5 12.4 21.4 11.8 10.1 15.1 24.4 12.0 12.6 15.8 10.4 17.2 15.1 17.2 17.8 12.8 21.2 16.7 20.5 11.1 15.3 33.5 16.7 14.0 22.3 15.3 15.1 11.8 12.2 14.2 9.0 21.2 13.6 12.6 16.0 21.3 11.7 51.8 16.8 19.4 20.6 9.2 16.7 17.1 11.3 12.5 8.6 15.0 13.0 12.1 20.5 8.3 13.9 23.0 13.8 14.3 20.8 17.1 12.9 15.5 17.8 21.2 16.9 18.9 21.4 16.6 16.5 14.0 16.0 12.7 19.9 21.0 10.9 7.5 7.3 15.9 13.3 15.4 14.2 16.5 18.9 15.7 31.4 25.7 17.7 12.3 7.5 18.6 52.4 16.4 13.4 11.3 9.8 19.5 11.9 20.6 20.6 21.5 19.6 20.2 35.1 11.0 9.6 22.8 9.4 12.9 34.0 14.0 13.6 14.9 15.9 22.3 46.3 14.7 15.1 28.1 9.6 7.2 15.0 14.7 8.4 20.5 12.5 13.8 20.0 8.0 11.8 8.5 12.0 9.5 12.1 13.0 8.6 14.0 8.3 12.5 18.2 11.0 23.3 17.2 15.1 16.7 20.5 22.3 16.8 ADAT2 "DEADC1, dJ20N2.1, TAD2" ENSG00000189007 "Adenosine deaminase, tRNA specific 2" Q7Z6V5 6 143422832-143450673 "Enzymes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035479 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA035479: AB_10611672" "unprognostic (2.24e-1)" "unprognostic (3.07e-3)" "unprognostic (1.55e-1)" "unprognostic (8.20e-2)" "unprognostic (3.05e-2)" "unprognostic (8.58e-2)" "unprognostic (1.07e-3)" "unprognostic (3.31e-2)" "unprognostic (1.34e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-2)" "unprognostic (9.28e-5)" "unprognostic (4.88e-2)" "unprognostic (6.96e-2)" "unprognostic (7.29e-2)" "unprognostic (4.08e-2)" 7.3 9.5 6.6 15.1 9.4 17.1 8.6 7.7 8.8 6.6 9.5 4.9 4.7 9.9 8.3 5.3 12.0 7.9 7.6 4.2 5.2 3.8 7.5 13.2 11.3 17.6 4.9 8.0 7.5 13.3 7.1 9.6 4.0 7.3 8.6 13.3 6.0 10.1 6.2 13.3 17.1 10.0 6.5 6.7 13.1 10.8 4.1 5.3 8.6 10.8 10.1 13.5 6.6 8.7 2.8 3.2 0.4 1.4 1.9 6.6 2.3 2.9 2.5 3.1 10.5 2.6 8.4 4.7 4.1 1.9 2.9 4.0 6.6 7.5 10.4 4.5 2.8 8.5 5.8 5.8 5.7 5.5 12.9 14.7 10.4 13.5 3.3 20.6 7.4 2.8 8.7 5.6 9.0 6.2 16.0 9.0 4.4 4.2 8.0 11.7 3.9 4.7 9.8 9.1 8.5 4.4 3.3 6.9 4.7 3.5 9.4 2.8 4.0 7.6 4.8 4.2 3.6 8.7 8.0 9.3 6.6 7.9 4.0 17.4 4.9 0.0 0.9 0.0 3.2 1.4 4.7 2.8 3.0 2.9 3.2 2.0 3.4 5.1 0.4 1.9 0.2 3.0 6.6 2.3 6.6 9.4 7.7 8.8 5.2 3.8 4.9 8.0 7.3 5.3 ADCK1 FLJ39600 ENSG00000063761 "AarF domain containing kinase 1" Q86TW2 14 77800083-77935012 "Enzymes, Predicted secreted proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051012, HPA055014" Uncertain Approved Nucleoplasm "Secreted - unknown location" Nucleoplasm "HPA051012: , HPA055014: " "unprognostic (6.36e-2)" "unprognostic (7.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavourable (1.70e-4)" "prognostic favourable (4.11e-5)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (4.57e-3)" "unprognostic (1.38e-1)" "prognostic favourable (5.82e-6)" "unprognostic (6.30e-3)" "unprognostic (2.06e-1)" "unprognostic (9.57e-2)" "unprognostic (4.06e-1)" 7.2 11.0 11.0 7.0 15.2 7.4 6.9 6.8 20.5 5.6 10.3 19.0 7.7 11.2 7.7 10.3 7.7 7.1 9.1 11.1 12.4 10.4 8.8 10.5 6.2 6.0 13.5 9.4 6.6 9.8 11.3 11.3 7.8 15.0 8.2 10.3 13.8 10.6 8.9 13.7 8.5 8.5 10.5 10.6 9.7 7.5 5.5 11.5 10.8 9.1 7.8 7.5 6.9 5.0 4.0 8.9 1.4 7.2 3.4 5.3 3.1 3.3 5.4 3.2 10.8 8.1 4.6 4.3 3.4 5.7 3.1 3.7 2.9 8.0 7.3 5.5 6.0 6.4 17.8 5.4 2.0 4.2 5.6 1.9 3.4 4.8 8.3 2.8 4.1 5.7 10.1 1.2 3.9 4.4 6.9 4.5 4.0 16.8 3.4 5.6 6.4 6.4 5.6 0.5 5.8 4.4 8.5 7.2 4.0 6.6 9.2 4.0 13.3 6.2 3.9 2.9 2.3 5.9 3.0 4.6 5.0 4.1 4.4 4.9 3.7 1.4 4.7 1.3 5.3 7.2 3.5 1.7 2.2 3.1 8.9 4.0 2.5 4.6 0.4 3.4 2.8 7.0 3.7 3.1 11.0 15.2 6.8 20.5 12.4 10.4 13.5 9.4 15.0 11.5 ADCK2 MGC20727 ENSG00000133597 "AarF domain containing kinase 2" Q7Z695 7 140673153-140696261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036036 Approved Uncertain Centrosome,Cytosol "Centrosome, Cytosol" "HPA036036: AB_10672078" "unprognostic (2.76e-1)" "unprognostic (1.79e-1)" "unprognostic (5.72e-2)" "unprognostic (5.30e-2)" "unprognostic (4.03e-3)" "unprognostic (1.52e-1)" "unprognostic (3.05e-2)" "unprognostic (7.48e-2)" "unprognostic (2.61e-1)" "unprognostic (7.10e-3)" "unprognostic (6.81e-3)" "unprognostic (9.36e-3)" "prognostic favourable (9.75e-5)" "unprognostic (1.89e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (2.13e-1)" 12.3 10.6 15.3 11.3 16.6 8.8 13.4 15.4 27.0 12.3 15.1 26.3 13.2 8.8 10.3 11.4 18.0 20.0 10.3 10.2 16.6 18.2 12.3 12.5 12.8 15.6 19.5 13.1 14.5 22.8 21.4 12.7 19.9 18.2 14.4 13.2 10.7 16.8 14.0 12.5 25.8 13.0 10.9 24.0 13.6 13.0 7.6 13.3 20.6 25.1 9.9 16.2 13.4 18.9 8.2 12.0 3.2 5.0 5.1 7.3 2.2 15.9 11.5 2.7 12.7 10.0 11.4 16.4 8.3 10.1 8.7 5.8 10.5 11.3 21.4 12.6 5.8 13.2 13.8 9.4 2.6 15.8 14.2 4.5 4.5 5.1 13.9 3.0 11.3 9.5 28.9 4.9 6.9 7.4 7.9 10.5 3.1 19.9 22.4 7.4 4.0 12.5 17.7 0.1 10.4 4.7 16.0 10.8 7.5 11.4 16.6 11.4 14.7 6.1 7.8 10.9 3.8 18.0 16.0 7.3 11.2 15.8 16.0 12.1 12.9 0.0 3.7 3.2 5.4 5.0 4.9 8.2 4.8 5.3 5.7 4.2 7.3 4.7 0.1 5.1 3.0 12.0 6.0 2.2 15.3 16.6 15.4 27.0 16.6 18.2 19.5 13.1 18.2 13.3 ADCK5 FLJ35454 ENSG00000173137 "AarF domain containing kinase 5" Q3MIX3 8 144373101-144393242 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025692, HPA028679" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA025692: AB_10599486, HPA028679: AB_10600226" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (8.96e-2)" "unprognostic (1.68e-2)" "unprognostic (1.00e-1)" "unprognostic (2.31e-3)" "unprognostic (6.45e-2)" "unprognostic (2.70e-1)" "unprognostic (4.25e-2)" "unprognostic (6.60e-2)" "unprognostic (2.03e-2)" "unprognostic (1.33e-3)" "unprognostic (1.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-1)" "unprognostic (2.90e-2)" 4.1 10.0 4.8 8.9 4.5 4.5 4.3 11.5 9.1 4.6 18.3 2.8 7.6 19.1 5.8 4.2 7.2 4.2 6.3 3.8 3.9 4.1 4.8 6.9 3.7 5.0 3.4 8.4 5.5 5.6 4.7 4.1 3.7 4.5 4.7 4.0 4.6 7.4 4.7 5.6 8.3 17.0 2.7 2.4 6.7 5.6 7.7 3.8 6.8 4.1 4.9 6.1 5.1 5.0 4.7 6.3 2.5 5.4 1.8 4.1 2.8 3.8 4.8 1.0 3.3 0.9 0.8 5.7 3.3 1.8 2.6 0.9 5.2 4.2 1.7 2.3 0.7 5.1 0.2 3.5 0.2 4.3 1.6 4.4 3.6 5.8 2.6 1.0 3.4 1.3 2.1 0.9 0.8 1.8 2.9 3.0 1.5 10.1 3.2 4.4 0.6 3.6 4.2 1.6 3.0 1.7 3.6 0.7 1.8 4.8 3.9 2.7 3.3 3.0 1.2 1.4 5.1 3.5 2.2 1.4 0.4 1.5 3.2 3.8 2.0 1.8 4.2 2.5 2.3 5.4 3.0 1.8 2.8 1.8 6.3 4.7 2.9 1.5 0.7 1.8 5.0 4.0 4.1 2.8 4.8 4.5 11.5 9.1 3.9 4.1 3.4 8.4 4.5 3.8 ADCY1 "AC1, DFNB44" ENSG00000164742 "Adenylate cyclase 1" Q08828 7 45574140-45723116 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, cAMP biosynthesis" "Calmodulin-binding, Lyase" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.0" "Cell line enhanced" "Detected in many" "hTERT-HME1: 15.0;SCLC-21H: 9.1;SH-SY5Y: 17.3;SK-MEL-30: 19.9;WM-115: 11.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018364, HPA068274" Uncertain Approved Mitochondria Mitochondria "CAB018364: AB_2223098, HPA068274: " "unprognostic (9.41e-3)" "unprognostic (7.30e-4)" "unprognostic (9.31e-2)" "unprognostic (2.98e-1)" "unprognostic (4.18e-2)" "unprognostic (3.07e-3)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (1.64e-3)" "unprognostic (2.89e-1)" "unprognostic (7.73e-3)" "unprognostic (1.54e-1)" "unprognostic (4.74e-6)" "unprognostic (2.49e-1)" "unprognostic (7.65e-3)" "unprognostic (2.87e-1)" "unprognostic (2.23e-1)" 2.8 2.8 11.5 0.7 11.7 0.4 6.8 22.7 29.0 7.8 0.9 2.0 0.0 0.7 2.7 1.1 1.2 2.4 1.2 4.0 11.6 4.0 1.8 9.6 1.0 0.8 5.8 13.4 1.2 3.6 1.0 1.5 0.9 6.2 4.1 1.0 5.0 0.8 2.1 9.2 0.6 0.7 1.6 2.2 1.0 1.8 3.9 1.2 0.0 3.0 0.2 0.8 1.0 1.5 0.5 0.4 0.6 0.1 0.0 0.2 0.0 0.5 3.8 1.4 2.2 2.8 0.0 2.7 0.1 0.0 0.5 0.2 0.4 0.0 0.0 0.2 0.1 1.2 2.5 0.1 0.0 6.9 1.8 0.0 0.0 0.3 0.0 0.1 0.0 3.4 1.9 0.3 15.0 0.1 0.2 4.6 0.2 4.6 0.0 0.0 5.6 0.0 0.0 0.0 7.5 0.0 3.7 9.1 17.3 1.4 0.0 19.9 1.3 2.3 0.0 0.4 2.9 0.3 2.3 0.0 0.0 0.0 0.0 0.0 11.3 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 11.5 11.7 22.7 29.0 11.6 4.0 5.8 13.4 6.2 1.2 ADCY10 "HCA2, RP1-313L4.2, SAC, SACI, Sacy" ENSG00000143199 "Adenylate cyclase 10" Q96PN6 1 167809388-167914215 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "liver: 14.9;testis: 38.6" "Cell line enhanced" "Detected in some" "BEWO: 2.6;T-47d: 4.9" "Cancer enhanced" "Detected in single" "liver cancer: 0.7" "Region enriched" "Detected in single" 5 "cerebellum: 1.6" "Cell type enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015243, HPA017749" Approved "HPA015243: AB_1856540, HPA017749: AB_1856541" "unprognostic (1.20e-1)" "unprognostic (2.53e-1)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" "unprognostic (2.05e-1)" "unprognostic (1.65e-1)" "unprognostic (5.35e-2)" "unprognostic (1.56e-1)" "unprognostic (1.63e-1)" "unprognostic (3.65e-1)" "unprognostic (4.43e-2)" "unprognostic (7.83e-5)" "unprognostic (5.86e-7)" "unprognostic (4.73e-2)" "unprognostic (1.33e-1)" "unprognostic (7.83e-2)" "unprognostic (2.59e-1)" 0.1 0.1 0.2 0.1 0.3 0.0 1.3 1.6 0.3 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.2 0.3 14.9 0.1 0.1 0.2 0.3 0.1 0.4 0.0 0.1 0.1 0.1 0.2 0.2 0.1 0.7 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 38.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 1.4 0.6 0.0 0.3 0.4 0.3 0.1 0.1 0.2 0.6 0.5 2.6 0.1 1.0 0.3 1.1 1.6 0.1 0.2 0.3 0.0 0.0 1.1 0.1 0.2 0.4 1.6 0.5 0.3 0.7 0.1 0.0 0.0 0.1 1.8 0.8 0.6 0.0 1.2 0.1 0.1 0.0 0.5 0.8 1.0 0.0 0.1 0.0 0.3 1.2 0.0 0.4 0.0 0.0 0.0 0.5 4.9 0.8 0.1 0.2 0.0 0.2 0.1 1.2 0.6 0.8 0.7 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.0 0.4 0.2 0.3 1.6 0.3 0.3 0.2 0.2 0.3 0.1 0.1 ADCY2 "AC2, HBAC2, KIAA1060" ENSG00000078295 "Adenylate cyclase 2" Q08462 5 7396208-7830081 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 35.9;skeletal muscle: 58.6" "Group enriched" "Detected in some" 7 "AF22: 9.2;NTERA-2: 7.0;SK-MEL-30: 7.7" "Cancer enhanced" "Detected in some" "glioma: 4.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031482, HPA038015, HPA038483" Approved "CAB031482: AB_630838, HPA038015: AB_10673653, HPA038483: AB_10675799" "unprognostic (6.48e-2)" "unprognostic (2.60e-2)" "unprognostic (1.49e-1)" "unprognostic (5.65e-2)" "unprognostic (3.77e-1)" "unprognostic (4.03e-4)" "unprognostic (1.94e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (7.68e-2)" "unprognostic (1.09e-5)" "unprognostic (1.05e-1)" "unprognostic (7.33e-3)" "unprognostic (4.90e-2)" "unprognostic (3.92e-3)" 1.8 3.3 16.8 1.3 14.5 1.2 2.8 6.6 35.9 4.9 1.9 6.7 0.7 1.9 3.9 1.7 4.0 4.1 2.1 1.2 14.5 9.4 1.2 1.1 1.3 1.1 12.8 10.0 5.1 1.9 1.0 5.1 1.8 11.3 6.2 1.6 2.0 1.5 5.1 58.6 6.3 1.8 4.3 12.5 1.2 2.6 3.6 5.4 0.0 1.1 5.1 1.2 1.9 2.1 0.9 0.4 1.5 0.4 0.3 0.6 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.0 0.0 0.1 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.7 0.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.4 0.1 0.4 0.2 0.4 0.5 0.3 0.3 0.1 0.9 0.4 0.6 1.5 0.3 0.3 0.4 0.2 0.0 16.8 14.5 6.6 22.5 14.5 9.4 12.8 10.0 11.3 5.4 ADCY3 AC3 ENSG00000138031 "Adenylate cyclase 3" O60266 2 24819169-24919839 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis, Olfaction, Sensory transduction" "Calmodulin-binding, Lyase" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010223 Approved "CAB010223: AB_630839" "unprognostic (3.05e-1)" "unprognostic (1.10e-1)" "unprognostic (4.91e-2)" "unprognostic (1.39e-3)" "unprognostic (5.01e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-1)" "unprognostic (6.06e-2)" "unprognostic (8.43e-2)" "unprognostic (6.89e-2)" "unprognostic (8.22e-3)" "unprognostic (2.52e-1)" "prognostic unfavourable (1.32e-9)" "unprognostic (3.74e-2)" "unprognostic (5.56e-2)" "unprognostic (1.11e-1)" "unprognostic (8.55e-3)" 35.8 8.2 14.4 11.7 26.0 13.2 41.2 15.0 21.7 22.5 15.1 16.5 6.5 7.6 23.3 15.6 17.4 21.4 18.2 18.2 13.7 13.1 9.5 4.6 15.3 13.7 29.6 14.1 29.5 7.7 15.4 16.2 58.6 16.3 15.1 11.7 11.3 8.7 24.9 7.9 14.8 12.3 25.1 12.4 11.7 9.8 11.3 18.2 4.3 14.4 13.9 12.8 13.5 24.2 7.2 11.0 3.2 1.8 1.1 3.1 1.2 28.0 19.3 6.3 10.6 32.0 25.5 12.2 14.1 20.7 12.3 11.3 15.6 9.7 9.8 3.2 20.6 20.6 15.4 19.2 8.6 22.3 20.5 16.0 21.2 2.0 24.3 9.1 10.1 21.3 16.3 12.3 18.7 11.3 8.0 17.2 7.2 20.1 8.8 2.1 6.8 8.4 15.6 32.9 20.3 5.3 16.8 10.2 7.5 17.6 21.0 12.1 5.4 7.6 10.8 21.6 15.5 12.5 21.2 17.9 41.6 38.3 7.0 14.4 13.4 3.2 1.8 0.0 0.6 1.8 0.3 6.4 1.4 0.5 11.0 7.2 0.7 0.6 0.0 1.1 0.4 10.1 3.1 1.2 14.4 26.0 15.0 21.7 13.7 13.1 29.6 14.1 16.3 18.2 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 9.7;TIME: 4.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "basophil: 5.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005070, HPA048344" Approved "CAB005070: AB_2273639, HPA048344: " "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favourable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavourable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 15.8 2.7 2.3 4.6 2.0 1.5 14.2 1.1 2.4 13.3 4.4 1.6 6.3 1.7 16.8 10.0 6.0 7.7 10.9 10.3 1.6 1.4 6.3 2.0 14.7 8.4 2.3 1.5 3.2 2.1 4.7 1.8 17.8 2.7 4.8 2.3 5.8 3.6 8.0 6.2 4.4 3.9 7.0 1.9 9.3 3.4 2.6 1.6 0.0 7.4 7.3 3.3 5.9 12.6 0.0 1.1 5.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.9 0.4 1.0 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.8 0.0 0.2 0.0 9.7 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 4.0 0.3 0.1 1.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 5.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 2.3 2.0 1.1 2.4 1.6 1.4 2.3 1.5 2.7 1.6 ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449758 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 69.9" "Cell line enhanced" "Detected in some" "MCF7: 17.6;RPMI-8226: 3.1;RPTEC TERT1: 6.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "basal ganglia: 347.3" "Region enriched" "Detected in all" 6 "basal ganglia: 205.1" "HPA017730, HPA077682" Uncertain Enhanced "Intermediate filaments" "Intermediate filaments" "HPA017730: AB_1844595, HPA077682: " "unprognostic (3.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.61e-3)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-2)" "unprognostic (1.48e-1)" "unprognostic (7.61e-2)" "unprognostic (2.49e-2)" "unprognostic (2.34e-1)" "unprognostic (7.27e-3)" "unprognostic (2.64e-2)" "prognostic favourable (7.46e-6)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (3.19e-2)" "unprognostic (5.97e-4)" 13.3 3.0 12.5 3.7 32.0 0.6 9.3 2.6 14.4 4.5 11.7 10.4 3.1 4.2 6.2 4.4 13.8 5.3 7.3 69.9 10.4 8.3 5.3 2.4 2.6 2.0 15.0 8.6 10.1 5.7 1.1 7.7 4.8 9.7 13.8 4.6 4.6 3.1 16.3 2.2 1.1 4.8 13.5 8.8 4.7 9.6 5.9 16.0 0.0 1.0 0.2 2.6 9.5 8.5 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.6 1.5 0.1 0.1 0.1 0.4 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.3 0.2 0.5 0.8 0.0 0.0 0.1 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 17.6 0.0 0.0 1.0 0.1 0.0 0.4 3.1 6.3 0.6 2.2 2.0 0.0 0.6 0.1 0.0 0.1 0.0 0.1 1.5 0.1 0.3 0.2 0.7 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 12.5 32.0 2.6 14.4 10.4 8.3 15.0 8.6 9.7 16.0 ADCY6 AC6 ENSG00000174233 "Adenylate cyclase 6" O43306 12 48766194-48789037 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 30.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018365 Approved Approved "Golgi apparatus" "Golgi apparatus" "CAB018365: AB_2257941" "unprognostic (1.18e-2)" "unprognostic (2.20e-2)" "unprognostic (6.89e-2)" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (3.68e-2)" "prognostic unfavourable (8.23e-4)" "unprognostic (1.55e-1)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.64e-2)" "unprognostic (5.06e-3)" "unprognostic (5.10e-3)" "unprognostic (1.09e-1)" "unprognostic (3.09e-1)" "unprognostic (2.48e-2)" 25.9 9.6 14.1 12.4 7.5 0.8 19.7 15.0 17.0 9.8 15.2 5.5 16.2 12.3 13.2 12.8 6.2 9.5 17.6 37.5 9.9 8.3 11.3 5.6 8.5 4.7 5.6 11.0 14.6 17.4 15.8 9.1 9.5 8.9 11.1 12.6 11.8 19.9 12.0 7.3 10.2 13.9 9.1 4.7 2.9 13.5 4.0 5.5 0.6 11.1 6.8 3.8 7.8 14.9 1.8 0.4 1.4 0.4 0.5 0.4 0.5 5.9 11.5 13.3 8.3 14.0 7.0 14.4 7.3 7.4 8.9 6.2 20.4 20.0 0.0 16.8 6.3 4.8 3.8 4.9 3.2 0.0 5.9 5.4 15.7 3.7 8.0 0.0 4.5 8.9 6.0 7.4 2.7 8.1 0.7 2.0 6.5 10.3 0.0 0.2 4.5 5.4 1.9 5.1 3.2 10.0 18.5 2.0 8.2 7.5 30.1 6.5 23.5 1.4 9.2 8.4 6.0 4.4 3.2 3.1 1.5 0.2 7.6 0.0 3.8 1.4 0.4 0.4 0.3 0.2 0.2 1.1 0.3 0.2 0.3 1.8 0.4 0.3 0.9 0.5 0.4 0.4 0.2 0.5 14.1 7.5 15.0 17.0 9.9 8.3 5.6 11.0 8.9 5.5 ADCY7 "AC7, KIAA0037" ENSG00000121281 "Adenylate cyclase 7" P51828 16 50246137-50318135 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 22.9;HMC-1: 63.9;RPMI-8226: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041218, HPA048241" Uncertain Approved Cytosol Cytosol "HPA041218: , HPA048241: " "unprognostic (1.98e-1)" "prognostic unfavourable (5.31e-4)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (3.77e-1)" "unprognostic (2.80e-1)" "unprognostic (3.90e-2)" "unprognostic (7.75e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.59e-3)" "unprognostic (7.34e-2)" "unprognostic (2.15e-3)" "unprognostic (2.18e-1)" "unprognostic (9.52e-4)" 6.3 4.3 7.0 17.4 9.7 14.9 3.9 1.2 5.2 3.7 5.0 9.8 0.8 2.8 3.7 4.8 13.2 5.3 6.9 7.3 5.3 4.2 3.3 3.6 16.4 16.5 8.8 4.4 17.1 3.7 1.0 3.4 9.7 8.6 3.5 5.9 6.2 6.5 1.6 1.8 7.9 10.4 5.0 12.3 26.9 4.9 2.1 9.2 21.8 3.7 3.1 26.0 6.6 6.1 3.6 12.5 6.5 16.7 8.4 7.0 5.0 3.9 5.4 0.2 0.7 0.5 7.0 0.5 2.8 1.3 2.1 2.0 5.1 8.2 1.6 7.4 11.1 14.3 5.6 2.4 2.7 15.1 2.0 22.9 4.1 1.4 6.4 4.3 63.9 3.7 2.3 1.6 2.5 0.6 8.3 3.2 3.0 2.3 1.6 10.2 0.9 7.7 1.6 2.1 31.7 1.5 0.3 0.9 2.6 1.5 0.6 1.3 0.1 12.8 5.0 0.3 7.5 0.8 0.7 0.3 0.1 3.5 2.4 9.3 1.0 6.5 7.8 2.9 7.0 11.7 5.1 3.2 2.8 5.0 12.5 3.6 2.6 3.7 4.4 8.4 16.7 6.5 3.9 5.0 7.0 9.7 1.2 5.2 5.3 4.2 8.8 4.4 8.6 9.2 ADCY8 "AC8, ADCY3, HBAC1" ENSG00000155897 "Adenylate cyclase 8" P40145 8 130780301-131042426 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.6;epididymis: 27.8" "Group enriched" "Detected in some" 5 "U-138 MG: 13.5;U-87 MG: 26.2" "Group enriched" "Detected in some" 5 "glioma: 6.0;ovarian cancer: 1.8;thyroid cancer: 1.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018652, HPA024291" Supported "CAB018652: AB_633654, HPA024291: AB_1844597" "unprognostic (5.59e-3)" "unprognostic (3.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "unprognostic (8.22e-3)" "unprognostic (4.91e-2)" "unprognostic (7.39e-3)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" "unprognostic (6.67e-2)" 0.2 0.2 8.2 0.2 5.1 0.2 0.9 5.3 9.6 0.8 0.2 1.2 1.4 0.2 0.3 27.8 0.2 4.8 0.2 0.3 6.4 6.2 0.5 0.2 1.6 0.2 7.8 0.6 0.3 0.2 0.2 0.0 0.2 5.7 0.2 0.2 0.0 2.8 2.0 0.2 1.5 0.2 0.9 5.0 0.2 0.3 0.7 1.1 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.3 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 5.1 5.3 5.0 6.4 6.2 7.8 0.6 5.7 1.1 ADCY9 AC9 ENSG00000162104 "Adenylate cyclase 9" O60503 16 3953387-4116185 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 36.4" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041328, HPA044225" Approved Approved Cytosol Cytosol "HPA041328: , HPA044225: " "unprognostic (1.78e-1)" "unprognostic (5.54e-2)" "unprognostic (2.57e-1)" "prognostic unfavourable (2.55e-5)" "unprognostic (6.62e-2)" "unprognostic (1.30e-2)" "unprognostic (2.52e-1)" "unprognostic (3.61e-2)" "unprognostic (6.93e-2)" "unprognostic (4.76e-3)" "unprognostic (5.40e-2)" "unprognostic (1.37e-1)" "prognostic favourable (5.24e-8)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (1.55e-2)" 5.2 4.8 7.1 3.2 10.9 0.9 5.4 8.5 9.6 7.0 6.4 4.1 4.4 6.5 6.5 4.4 6.8 7.7 6.5 13.3 6.2 3.0 8.0 9.6 11.1 2.5 3.0 6.2 9.4 12.5 12.3 5.8 7.8 7.7 3.6 5.5 9.0 10.1 5.0 36.4 4.4 10.9 6.3 2.2 3.2 5.5 4.4 3.4 0.7 21.8 7.7 3.0 7.9 4.8 0.1 1.0 3.2 1.5 1.0 1.9 0.9 4.8 7.5 2.3 4.2 8.2 10.1 3.4 8.6 9.0 4.8 3.9 6.2 4.3 0.0 13.3 23.6 4.8 8.9 5.4 3.3 6.0 8.6 0.2 17.2 11.9 8.9 0.6 3.9 10.7 8.3 5.6 3.0 3.2 2.6 0.0 4.9 8.9 0.0 2.5 4.1 4.1 7.7 10.9 0.2 1.7 1.3 5.2 2.3 6.7 7.9 5.8 20.1 8.7 3.0 9.7 2.7 9.4 3.7 1.9 1.1 1.0 2.1 2.6 3.7 3.2 1.5 1.0 1.9 1.5 1.7 0.0 0.6 0.6 0.1 0.1 0.1 1.1 0.3 1.0 0.0 1.0 0.0 0.9 7.1 10.9 8.5 9.6 6.2 3.0 3.0 6.2 7.7 3.4 ADGB "C6orf103, CAPN16, dJ408K24.1, FLJ23121" ENSG00000118492 Androglobin Q8N7X0 6 146598965-146815462 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 20.9;epididymis: 13.1;testis: 30.6" "Cell line enriched" "Detected in single" 25 "HDLM-2: 17.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basal ganglia: 6.6;pons and medulla: 20.9" "Cell type enriched" "Detected in single" 10 "myeloid DC: 2.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 2.6" "Low region specificity" "Detected in all" "HPA036340, HPA036341" Enhanced Uncertain Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA036340: , HPA036341: AB_10672241" "unprognostic (4.15e-3)" "unprognostic (1.23e-2)" "unprognostic (9.30e-3)" "unprognostic (1.09e-1)" "unprognostic (2.07e-2)" "unprognostic (3.11e-2)" "unprognostic (5.05e-1)" "unprognostic (2.34e-1)" "unprognostic (4.83e-3)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (1.77e-2)" "unprognostic (3.66e-2)" "unprognostic (2.68e-1)" 0.1 0.1 1.6 0.1 6.6 0.1 0.2 0.0 0.2 1.0 0.5 5.1 0.0 0.1 0.4 13.1 0.2 9.8 0.1 0.1 2.2 2.7 0.2 0.2 4.8 0.2 0.0 0.0 4.3 0.1 0.3 0.8 0.2 20.9 0.2 0.4 0.0 0.1 0.3 0.1 0.3 0.1 0.1 0.4 0.1 0.2 30.6 1.2 0.0 0.2 0.1 0.2 0.1 0.0 0.0 2.6 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 6.6 0.0 0.1 2.2 2.7 0.0 0.0 20.9 1.2 ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276367-99291028 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 322 "liver: 250.3" "Cell line enriched" "Detected in some" 5 "ASC diff: 10.9" "Cancer enriched" "Detected in some" 251 "liver cancer: 165.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Plasma membrane,Cytosol" 12000000 "Plasma membrane, Cytosol" "CAB009562: AB_2257984, HPA047814: , HPA060902: " "unprognostic (5.89e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "prognostic favourable (2.38e-4)" "unprognostic (2.78e-3)" "unprognostic (4.25e-1)" "unprognostic (4.79e-3)" "unprognostic (6.21e-2)" "unprognostic (9.36e-2)" "unprognostic (3.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 250.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 10.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304964-99352760 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adipose tissue: 253.5;liver: 466.3" "Cell line enriched" "Detected in some" 7 "ASC diff: 385.0" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Group enriched" "Detected in some" 5 "midbrain: 2.3;pons and medulla: 1.6" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" 16000000 "Plasma membrane, Cytosol" "HPA047814: , HPA060902: " "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavourable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" 253.5 12.3 0.2 21.8 0.0 0.4 78.7 0.2 0.4 18.3 60.0 0.4 5.7 3.5 12.8 14.4 33.5 22.3 31.9 24.2 0.3 0.0 9.2 466.3 43.8 17.5 2.3 0.1 18.0 8.7 0.8 5.3 0.9 1.6 30.7 10.1 2.3 11.2 3.9 20.5 11.9 25.4 30.8 2.4 5.9 10.9 18.0 0.2 0.2 16.1 9.7 2.0 42.3 76.0 0.6 0.2 1.2 0.3 0.8 0.4 0.0 0.0 0.0 0.0 0.0 385.0 56.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.3 0.2 0.1 0.1 0.2 0.4 0.1 0.0 0.6 0.3 0.4 1.2 0.8 0.1 0.2 0.1 0.0 0.2 0.0 0.2 0.0 0.3 0.0 2.3 0.1 1.6 0.2 ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336492-99353027 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 47.1;liver: 149.4;stomach 1: 43.1" "Group enriched" "Detected in some" 4 "ASC TERT1: 5.1;HSkMC: 15.1" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" 9700000 "Plasma membrane, Cytosol" "HPA047814: , HPA060902: " "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favourable (4.55e-4)" "prognostic favourable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" 4.7 0.0 0.0 18.5 0.0 0.0 1.1 0.0 0.0 1.1 37.9 0.0 1.1 43.4 0.3 1.2 1.7 0.0 12.0 2.0 0.0 8.3 149.4 1.1 0.0 0.2 0.0 1.1 11.4 0.0 0.0 0.0 0.0 2.5 13.6 0.0 1.1 0.8 6.0 0.0 47.1 0.9 0.5 0.0 43.1 1.6 0.0 0.0 0.5 2.0 0.2 1.3 0.7 0.2 0.2 0.3 0.1 0.1 0.3 0.1 0.0 2.2 0.0 0.1 1.7 5.1 1.1 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.3 0.1 0.5 1.4 0.3 15.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.9 0.4 0.1 0.1 0.9 2.1 0.9 0.0 0.4 1.6 0.7 0.8 0.0 0.2 0.0 0.1 0.0 0.6 0.3 0.2 0.1 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.3 0.1 0.0 0.2 0.0 0.1 ADH4 ADH-2 ENSG00000198099 "Alcohol dehydrogenase 4 (class II), pi polypeptide" P08319 4 99123657-99157792 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "liver: 345.2" "Cell line enriched" "Detected in some" 11 "Hep G2: 21.9" "Cancer enriched" "Detected in some" 60 "liver cancer: 230.7" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020525 Enhanced Uncertain Nucleoplasm,Cytosol 5300000 "Nucleoplasm, Cytosol" "HPA020525: AB_1844609" "unprognostic (2.75e-1)" "unprognostic (1.69e-2)" "unprognostic (1.85e-2)" "unprognostic (5.54e-3)" "unprognostic (2.14e-2)" "unprognostic (1.33e-2)" "prognostic favourable (7.08e-6)" "unprognostic (1.49e-1)" "unprognostic (1.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.88e-1)" "unprognostic (2.34e-2)" "unprognostic (7.16e-3)" "unprognostic (2.20e-1)" "unprognostic (5.89e-3)" 0.3 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.2 3.6 0.0 0.1 11.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.2 345.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.4 0.1 4.5 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.8 0.1 0.1 0.5 1.2 0.7 2.8 0.5 0.4 0.9 0.1 0.3 0.3 0.2 0.3 0.4 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.2 0.5 0.3 0.0 0.3 0.0 0.2 0.4 0.2 0.1 0.5 0.8 21.9 0.1 1.8 0.5 0.3 0.0 0.2 0.2 0.1 0.4 1.0 0.1 0.3 0.3 0.6 0.3 0.2 0.2 1.8 0.5 0.2 0.4 0.2 0.3 2.0 0.3 0.0 0.5 0.0 0.4 0.5 0.2 0.4 0.1 0.6 0.4 0.7 0.1 0.7 0.1 2.8 0.4 0.5 0.9 0.5 0.8 0.4 0.5 0.5 0.1 1.2 0.8 0.8 1.0 0.4 0.5 0.7 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044578, HPA061919" Approved 6800000 "HPA044578: , HPA061919: AB_2684638" "unprognostic (1.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-3)" "prognostic favourable (9.90e-5)" "unprognostic (2.63e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "prognostic unfavourable (3.54e-4)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "prognostic favourable (4.58e-10)" "unprognostic (1.79e-3)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" 35.6 19.8 17.3 18.5 18.5 6.3 28.6 11.2 22.3 34.1 39.4 19.8 17.0 24.9 53.8 40.3 43.5 28.6 20.8 31.9 13.7 16.6 46.6 69.7 19.9 15.3 15.7 16.1 39.1 12.8 10.5 15.1 19.9 18.6 45.0 27.7 28.7 17.3 35.9 20.7 13.8 28.5 43.6 13.5 20.5 27.0 27.2 10.0 35.2 30.4 18.4 18.6 60.0 22.0 13.9 12.5 18.2 11.1 26.2 25.3 17.0 15.7 12.9 38.1 21.4 69.2 64.4 22.9 26.2 46.3 28.5 24.9 14.7 18.7 18.2 15.3 37.8 13.5 26.2 36.4 27.5 13.1 11.0 12.6 17.5 57.9 67.1 22.0 10.3 57.9 28.3 21.3 16.9 21.9 23.3 10.4 37.5 17.9 29.6 19.8 30.6 15.5 21.7 21.3 9.6 45.0 18.4 14.6 19.1 15.8 18.8 28.6 15.2 15.5 16.4 26.0 16.5 16.9 18.0 11.0 13.6 25.3 26.7 14.6 26.3 9.8 11.1 18.2 18.4 9.8 16.7 13.9 20.3 17.1 12.5 13.1 19.9 18.3 1.6 26.2 7.1 10.8 25.3 17.0 17.3 18.5 11.2 22.3 13.7 16.6 15.7 16.1 18.6 10.0 ADH6 ADH-5 ENSG00000172955 "Alcohol dehydrogenase 6 (class V)" P28332 4 99202638-99219537 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 123.3" "Cell line enriched" "Detected in some" 5 "Hep G2: 30.5" "Cancer enriched" "Detected in many" 18 "liver cancer: 46.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA067946, HPA069081" Enhanced 480000 "HPA067946: AB_2732776, HPA069081: AB_2732127" "unprognostic (1.38e-2)" "unprognostic (1.83e-2)" "unprognostic (5.82e-2)" "unprognostic (1.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.11e-3)" "unprognostic (2.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.35e-1)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (8.74e-3)" "unprognostic (3.86e-3)" 0.1 0.1 0.1 1.1 0.1 0.0 0.1 0.1 0.1 0.1 6.0 0.0 0.0 7.2 0.1 0.2 0.2 1.5 5.6 0.1 0.1 0.1 10.6 123.3 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.1 1.4 0.0 0.1 0.0 0.1 0.6 23.7 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.5 0.0 1.3 0.1 0.2 0.2 0.3 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 6.4 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.0 0.3 0.1 0.2 1.3 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 75.0;lymphoid tissue: 30.7;tongue: 68.7" "Group enriched" "Detected in some" 7 "ASC TERT1: 3.9;HaCaT: 4.4" "Group enriched" "Detected in some" 17 "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4;urothelial cancer: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 75.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 9.4 0.0 0.0 0.1 0.0 68.7 30.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADHFE1 "ADHFe1, FLJ32430" ENSG00000147576 "Alcohol dehydrogenase, iron containing 1" Q8IWW8 8 66430185-66471601 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.5" "Cell line enhanced" "Detected in some" "ASC diff: 4.6;HHSteC: 3.0;HSkMC: 2.7;RPTEC TERT1: 4.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023062 Enhanced Approved Vesicles Vesicles "HPA023062: AB_1844611" "prognostic favourable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favourable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favourable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" 12.5 3.2 10.3 2.2 9.7 1.8 4.3 2.2 10.7 5.9 3.8 10.9 4.8 2.7 4.2 8.6 3.1 5.9 5.0 34.6 6.9 5.4 11.8 44.5 3.6 2.3 8.6 7.5 5.2 8.3 11.6 9.8 3.7 6.9 7.3 3.1 10.7 6.6 10.5 35.7 2.4 2.4 6.9 4.8 2.8 8.6 3.2 7.3 0.0 4.5 12.9 2.5 6.2 1.9 1.3 0.4 3.4 1.1 2.2 2.6 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.5 0.4 0.3 0.0 0.0 1.7 0.0 0.0 0.7 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 3.0 0.0 0.2 2.7 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.9 0.0 0.5 1.2 2.0 0.0 0.0 0.3 0.2 0.0 0.0 1.2 0.1 0.1 0.8 0.0 0.3 3.4 1.1 0.0 2.6 0.0 2.4 1.3 0.5 2.2 0.4 0.8 0.7 2.2 0.1 2.2 0.0 0.3 0.0 0.6 10.3 9.7 2.2 7.8 6.9 5.4 8.6 7.5 6.9 7.3 ADI1 "APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL" ENSG00000182551 "Acireductone dioxygenase 1" Q9BV57 2 3497361-3519736 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 127.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035403, HPA035404" Approved Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA035403: AB_10603576, HPA035404: " "unprognostic (2.19e-2)" "unprognostic (1.68e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "unprognostic (3.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-3)" "unprognostic (4.23e-3)" "unprognostic (2.36e-3)" "unprognostic (4.00e-3)" "unprognostic (2.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (1.56e-1)" "unprognostic (9.94e-2)" "unprognostic (6.76e-2)" "unprognostic (8.74e-2)" 13.5 19.1 10.8 9.0 11.5 6.4 15.1 5.2 9.2 12.5 60.6 9.3 29.9 27.3 11.7 17.8 16.3 11.4 35.5 49.5 9.0 7.9 42.6 127.7 10.8 12.4 11.3 9.4 12.8 14.7 9.2 8.4 18.7 9.6 24.5 11.8 10.7 22.7 27.0 43.1 7.9 38.9 17.3 11.7 16.6 18.3 8.0 7.9 4.9 12.9 18.9 10.4 14.7 17.9 14.2 37.8 64.7 26.5 10.1 17.7 32.2 12.0 14.7 13.3 10.6 46.7 22.8 24.9 25.2 32.6 27.4 19.9 20.9 13.8 5.7 39.9 26.7 11.0 15.7 11.8 14.1 10.2 35.1 17.6 9.5 33.8 39.1 18.2 39.5 25.2 15.7 12.8 16.0 17.2 13.1 10.0 21.5 27.1 6.1 32.1 11.6 23.0 6.5 8.5 32.4 19.0 18.0 14.9 15.0 13.9 14.7 9.6 15.6 19.3 14.3 18.9 7.7 9.2 14.1 9.9 23.9 23.4 13.9 28.3 9.9 14.2 26.5 64.7 6.3 25.2 6.8 14.2 14.9 5.9 25.6 11.2 17.7 5.9 12.3 10.1 22.0 37.8 13.8 32.2 10.8 11.5 5.2 9.2 9.0 7.9 11.3 9.4 9.6 7.9 ADK AK ENSG00000156110 "Adenosine kinase" P55263 10 74151185-74709303 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Purine salvage" "Kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 71.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032876, HPA038391, HPA038409" Approved Supported Nucleoplasm,Cytosol 320000 "Nucleoplasm, Cytosol" "CAB032876: AB_2242229, HPA038391: , HPA038409: AB_10675798" "unprognostic (1.55e-3)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.62e-2)" "unprognostic (2.52e-2)" "prognostic unfavourable (1.93e-4)" "prognostic favourable (9.91e-4)" "unprognostic (2.64e-1)" "unprognostic (2.88e-1)" "unprognostic (1.55e-1)" "unprognostic (8.15e-3)" "unprognostic (2.51e-1)" "unprognostic (1.89e-3)" "unprognostic (2.03e-1)" "unprognostic (2.88e-2)" "unprognostic (4.97e-3)" "unprognostic (2.95e-2)" 13.8 10.7 11.8 13.6 25.4 12.1 14.5 11.2 11.8 9.5 9.3 9.0 9.6 8.8 6.6 10.6 29.4 8.9 6.3 15.7 9.8 11.1 19.0 71.9 15.1 17.9 12.3 9.3 5.2 12.6 15.1 23.5 43.2 11.6 8.7 10.8 8.5 13.1 11.4 18.1 20.8 6.4 8.3 13.2 11.3 7.4 11.9 10.3 13.4 20.8 24.1 21.9 12.6 14.7 49.3 23.0 5.4 21.6 6.5 15.7 9.8 37.5 8.5 9.0 12.0 9.0 13.9 20.7 32.6 25.9 25.3 28.4 23.7 39.2 19.7 8.2 13.1 34.4 10.5 34.7 40.6 13.2 12.1 12.5 13.9 25.5 10.3 20.0 5.1 12.8 23.0 18.4 45.9 22.0 9.9 6.4 19.0 21.0 23.5 27.1 2.5 60.0 22.7 15.6 16.9 27.7 20.7 7.1 8.4 14.3 55.8 10.8 37.1 15.1 18.8 8.4 15.5 22.4 26.9 9.2 10.4 22.2 15.9 28.8 5.1 1.3 10.1 1.4 4.5 18.0 10.0 29.7 9.5 8.2 23.0 49.3 7.9 6.5 5.4 6.5 21.6 16.7 15.7 9.8 11.8 25.4 11.2 11.8 9.8 11.1 12.3 9.3 11.6 10.3 ADO "C10orf22, FLJ14547" ENSG00000181915 "2-aminoethanethiol dioxygenase" Q96SZ5 10 62804857-62808483 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039194, HPA040437" Approved "HPA039194: AB_10794994, HPA040437: AB_10795633" "unprognostic (4.41e-2)" "unprognostic (1.44e-1)" "unprognostic (9.25e-2)" "unprognostic (1.73e-2)" "unprognostic (1.54e-2)" "unprognostic (1.57e-1)" "prognostic unfavourable (8.01e-5)" "unprognostic (4.48e-2)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "unprognostic (4.24e-2)" "unprognostic (8.64e-2)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "unprognostic (7.46e-2)" "unprognostic (2.64e-1)" "unprognostic (4.59e-2)" 8.9 9.2 12.1 7.5 14.4 4.4 9.8 15.9 22.9 9.5 7.4 18.4 4.1 7.2 10.1 14.3 7.2 7.7 8.7 14.5 14.6 9.7 11.9 7.6 7.9 9.3 20.2 11.0 11.6 8.2 13.0 5.0 7.5 15.6 10.6 6.9 7.4 6.4 9.9 11.6 6.3 6.9 9.8 37.7 8.8 7.4 36.1 12.4 10.0 12.7 6.1 10.0 8.0 10.2 4.0 3.0 2.7 4.3 2.4 2.8 1.4 6.5 4.9 9.8 16.0 10.8 8.2 5.7 8.2 9.8 8.9 9.7 7.6 5.3 6.2 4.3 8.4 10.1 10.1 6.3 9.5 8.3 7.6 4.2 5.1 6.4 11.1 14.5 11.0 7.0 12.3 9.3 15.2 6.7 7.7 6.0 11.8 6.3 9.3 14.2 9.0 47.7 11.1 7.8 3.8 8.6 4.2 10.2 16.8 8.3 11.5 16.4 7.4 10.0 5.7 9.0 9.2 7.2 13.5 11.0 20.3 10.0 10.9 15.4 5.7 2.7 2.7 0.8 1.4 4.3 2.8 4.0 1.9 2.1 3.0 3.0 1.7 2.8 0.0 2.4 3.0 2.0 1.0 1.4 12.1 14.4 15.9 22.9 14.6 9.7 20.2 11.0 15.6 12.4 ADPGK "ADP-GK, DKFZp434B195" ENSG00000159322 "ADP dependent glucokinase" Q9BRR6 15 72751369-72785846 "Enzymes, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045194, HPA058525" Approved Approved Centrosome "Intracellular and membrane" 35000 Centrosome "HPA045194: AB_10964638, HPA058525: " "unprognostic (5.96e-3)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.82e-1)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.45e-1)" "unprognostic (8.50e-2)" "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.21e-1)" "prognostic unfavourable (2.22e-4)" "prognostic unfavourable (4.52e-7)" "unprognostic (1.92e-1)" "unprognostic (6.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.07e-2)" 15.3 13.5 6.7 16.4 10.7 23.1 13.2 7.8 11.7 10.2 11.3 14.9 11.2 8.9 9.5 14.3 11.1 11.0 12.0 9.3 7.0 9.0 13.3 12.8 18.7 19.8 11.7 6.3 10.7 15.2 4.9 9.1 18.2 13.4 14.2 13.7 20.4 15.8 9.8 7.5 10.9 13.1 8.9 9.8 21.4 10.5 10.7 8.8 19.6 12.0 7.8 21.2 12.3 9.6 14.2 32.0 22.2 30.3 13.8 13.0 22.6 6.6 14.0 7.5 8.8 17.0 12.9 10.1 19.6 19.1 20.5 28.5 7.9 17.7 12.7 14.6 12.2 18.2 21.2 10.2 15.4 12.4 14.5 9.4 4.1 7.4 10.9 21.7 14.1 14.0 6.0 10.8 10.1 11.9 9.9 21.7 12.4 4.2 6.7 9.7 11.1 6.6 7.9 12.2 17.5 10.6 7.8 5.4 5.6 17.9 7.4 9.4 7.1 26.3 9.7 10.3 8.6 39.0 17.7 22.0 41.9 12.6 18.1 21.4 17.1 22.2 30.3 21.9 10.6 21.0 13.0 14.2 9.7 10.7 32.0 12.5 8.5 9.8 12.0 13.8 17.1 24.4 7.6 22.6 6.7 10.7 7.8 11.7 7.0 9.0 11.7 6.3 13.4 8.8 ADPRH ARH1 ENSG00000144843 "ADP-ribosylarginine hydrolase" P54922 3 119579268-119589945 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 15.7;HEL: 11.3;HMC-1: 12.7;Karpas-707: 17.3;U-266/70: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001701, HPA036961" Approved Approved "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "CAB001701: , HPA036961: " "prognostic favourable (2.42e-4)" "unprognostic (2.29e-1)" "unprognostic (4.77e-1)" "unprognostic (2.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.65e-1)" "unprognostic (3.06e-2)" "unprognostic (2.63e-1)" "unprognostic (4.24e-2)" "unprognostic (3.31e-3)" "unprognostic (1.88e-1)" "unprognostic (1.71e-1)" "unprognostic (6.04e-2)" "unprognostic (2.60e-3)" "unprognostic (8.87e-2)" "unprognostic (2.03e-1)" "unprognostic (4.35e-2)" 14.3 8.5 2.3 10.9 4.6 2.5 14.8 1.2 2.4 7.1 6.2 4.7 14.6 1.9 7.9 6.2 5.0 5.4 6.6 8.4 2.3 2.4 5.1 5.5 17.4 18.9 3.7 2.7 3.6 11.9 8.1 2.8 23.0 4.0 6.3 3.9 6.8 6.5 14.5 19.7 3.1 6.4 8.8 4.7 13.6 5.1 4.1 3.6 5.3 7.4 5.8 12.0 7.1 6.9 8.2 8.0 13.3 13.0 3.4 9.6 4.9 1.5 2.0 0.4 0.0 1.7 1.9 0.0 1.4 0.3 1.2 1.6 0.6 1.3 0.4 0.6 2.1 0.1 1.4 0.0 1.1 15.7 0.1 11.3 0.2 0.0 2.7 0.0 12.7 2.8 0.0 0.6 0.0 4.9 1.0 17.3 7.4 0.5 0.0 2.7 4.7 3.9 0.0 5.6 0.7 0.7 0.6 0.3 0.0 0.0 0.1 4.2 3.0 7.0 4.0 0.0 0.8 3.1 0.3 16.9 3.7 0.0 2.1 0.0 3.1 7.8 13.0 13.3 0.6 12.0 0.6 8.2 1.4 1.3 8.0 4.9 0.2 0.6 0.4 3.4 9.2 7.0 9.6 4.9 2.3 4.6 1.2 2.4 2.3 2.4 3.7 2.7 4.0 3.6 ADPRHL2 "ARH3, FLJ20446" ENSG00000116863 "ADP-ribosylhydrolase like 2" Q9NX46 1 36088875-36093932 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026641, HPA026739, HPA027104, HPA027141" Approved Enhanced Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA026641: , HPA026739: , HPA027104: AB_10601330, HPA027141: AB_1844619" "unprognostic (3.22e-3)" "unprognostic (5.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.61e-2)" "unprognostic (5.98e-2)" "unprognostic (2.09e-1)" "prognostic unfavourable (2.10e-7)" "unprognostic (3.71e-2)" "unprognostic (2.63e-1)" "unprognostic (5.34e-2)" "unprognostic (3.17e-2)" "unprognostic (7.80e-2)" "prognostic unfavourable (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (9.31e-2)" "unprognostic (3.65e-2)" "unprognostic (4.74e-2)" 15.5 27.6 17.4 15.2 17.4 16.9 20.0 16.5 22.7 15.9 17.3 30.3 17.7 15.6 14.3 17.8 26.3 28.4 13.5 15.1 19.1 18.9 19.8 16.5 20.7 19.1 25.8 18.5 19.7 27.6 15.1 14.0 20.9 19.7 16.6 12.9 12.2 21.9 20.2 26.4 24.4 17.7 22.2 23.5 18.0 14.1 25.1 20.0 21.2 21.2 22.3 19.7 16.1 15.9 27.7 38.9 34.1 38.8 23.5 29.3 29.2 25.2 10.7 12.8 18.0 11.8 8.6 18.3 18.8 15.9 30.5 30.1 12.7 23.0 18.1 18.5 18.8 15.8 16.1 28.9 18.3 12.9 20.2 16.4 13.0 16.9 22.3 18.6 9.8 10.1 22.1 27.6 12.1 19.3 14.1 15.0 14.2 12.2 18.8 28.3 27.5 22.2 15.4 13.5 18.2 27.3 20.8 15.7 24.9 13.8 14.5 30.7 14.9 16.2 13.2 17.7 18.2 24.4 24.9 19.5 18.7 16.0 25.5 18.6 10.8 18.2 32.4 34.1 25.5 38.7 24.0 23.6 27.9 29.3 38.9 27.7 28.3 24.0 31.4 23.5 38.8 24.6 22.8 29.2 17.4 17.4 16.5 22.7 19.1 18.9 25.8 18.5 19.7 20.0 ADPRM "C17orf48, MDS006" ENSG00000170222 "ADP-ribose/CDP-alcohol diphosphatase, manganese dependent" Q3LIE5 17 10697594-10711233 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023265, HPA023820" Approved "HPA023265: AB_1845590, HPA023820: AB_1845591" "unprognostic (7.58e-3)" "prognostic favourable (1.69e-4)" "unprognostic (1.42e-1)" "prognostic favourable (2.38e-5)" "unprognostic (2.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.43e-1)" "unprognostic (6.26e-3)" "unprognostic (2.97e-1)" "unprognostic (6.53e-3)" "unprognostic (2.65e-2)" "unprognostic (1.83e-1)" "unprognostic (4.77e-2)" "unprognostic (5.97e-2)" 11.1 8.2 6.4 9.3 13.1 12.9 13.0 9.8 12.2 10.3 8.1 10.1 16.1 6.6 11.3 9.1 7.8 9.0 7.9 6.4 9.6 6.1 7.8 15.2 6.9 23.2 8.1 5.6 14.2 12.4 4.2 11.9 4.9 9.3 16.7 7.5 8.3 8.8 13.4 14.8 9.2 9.9 6.5 7.3 10.5 12.2 9.5 8.2 18.8 14.6 10.4 11.1 8.8 9.0 10.5 4.2 6.1 3.5 4.0 18.7 5.9 4.1 2.2 4.5 5.3 10.4 13.4 2.2 7.8 8.7 5.7 8.6 1.3 1.9 8.0 4.2 8.2 3.4 1.9 5.6 6.8 5.1 5.3 5.8 3.6 4.4 18.6 3.0 5.4 15.4 10.3 6.0 9.0 10.0 3.9 1.5 8.2 1.1 3.8 5.3 3.7 2.1 3.4 5.2 2.4 10.0 3.0 1.0 6.3 4.1 1.6 9.7 3.8 5.9 10.2 4.0 2.4 4.4 5.2 2.0 1.4 2.3 7.8 4.4 6.7 3.4 3.5 6.1 3.2 3.0 5.4 8.2 8.8 5.8 4.2 10.5 18.7 12.0 2.5 4.0 3.1 2.4 7.7 5.9 6.4 13.1 9.8 12.2 9.6 6.1 8.1 5.6 9.3 8.2 ADSL ENSG00000239900 "Adenylosuccinate lyase" P30566 22 40346500-40390463 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" Lyase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 79.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000525, CAB019285" Enhanced Enhanced Cytosol 180000 Cytosol "CAB019285: , HPA000525: AB_1078106" "unprognostic (2.80e-1)" "unprognostic (2.12e-1)" "prognostic favourable (2.38e-4)" "unprognostic (2.64e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" "prognostic unfavourable (5.81e-8)" "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (3.99e-1)" "unprognostic (6.28e-2)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (8.43e-2)" "unprognostic (2.70e-1)" "unprognostic (4.06e-1)" "unprognostic (1.44e-2)" 9.3 11.6 5.0 13.7 8.5 11.2 9.0 6.8 10.1 7.9 9.5 7.3 4.4 6.0 10.8 9.4 9.7 9.0 6.9 14.6 4.5 4.7 12.0 17.3 6.8 17.6 4.9 4.9 10.5 21.8 5.4 9.1 9.5 5.1 7.1 9.7 9.2 14.7 6.4 79.0 6.2 9.4 10.7 4.9 14.5 9.6 10.9 4.4 18.8 8.4 23.6 15.5 9.5 7.4 15.3 28.8 11.0 22.7 19.8 34.0 24.6 21.0 24.9 21.4 30.5 14.5 20.4 24.8 19.3 19.1 41.8 32.0 41.1 12.4 61.3 16.4 22.3 15.9 47.7 31.0 43.0 16.3 44.9 27.8 28.1 37.8 30.3 90.4 23.4 21.9 17.6 36.7 39.0 30.9 32.8 26.9 31.2 23.5 27.9 32.3 34.9 26.6 42.6 45.0 43.5 26.9 16.7 13.8 13.6 23.0 12.7 36.5 17.6 28.6 20.4 22.4 41.5 19.7 36.9 25.6 44.6 47.0 18.6 33.6 21.8 11.0 19.3 7.8 16.2 22.7 22.8 15.3 34.0 21.7 28.8 14.9 27.0 20.8 1.9 19.8 20.2 14.9 34.0 24.6 5.0 8.5 6.8 10.1 4.5 4.7 4.9 4.9 5.1 4.4 ADSS ENSG00000035687 "Adenylosuccinate synthase" P30520 1 244408494-244452134 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024400 Supported Supported "Plasma membrane,Cytosol" 620000 Cytosol "Plasma membrane" "HPA024400: AB_1844623" "unprognostic (4.24e-3)" "unprognostic (2.63e-1)" "unprognostic (3.95e-2)" "unprognostic (8.68e-2)" "unprognostic (6.91e-2)" "unprognostic (2.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.10e-1)" "unprognostic (1.35e-1)" "unprognostic (7.62e-2)" "unprognostic (1.86e-1)" "unprognostic (2.04e-1)" "unprognostic (1.18e-2)" 19.4 17.8 23.2 23.8 31.2 29.2 26.3 18.3 26.3 20.9 20.9 35.9 27.1 21.1 18.9 23.3 27.7 18.3 15.8 9.8 24.9 23.4 25.1 19.3 19.2 21.2 42.5 16.6 20.9 21.2 26.6 17.7 21.0 34.9 19.8 22.7 13.1 25.0 21.7 11.0 26.5 23.2 22.9 29.3 24.9 24.7 48.9 36.7 26.7 26.3 17.9 24.8 26.5 21.8 10.9 13.6 24.6 21.3 15.5 16.0 11.9 25.4 14.1 12.3 10.8 14.4 20.7 22.7 25.8 21.7 18.5 14.1 18.5 24.7 22.8 17.1 19.8 19.3 13.4 16.8 20.8 16.9 23.7 15.2 14.1 14.0 17.4 35.8 19.6 14.1 20.4 17.2 17.5 66.0 26.3 17.0 18.4 6.1 23.0 24.1 32.7 15.6 21.3 11.7 24.6 30.7 15.9 16.7 14.7 21.9 20.4 25.7 14.1 19.1 28.8 17.2 9.4 19.8 26.7 20.6 27.0 17.2 14.2 42.1 25.3 24.6 15.8 13.0 15.0 20.5 16.0 10.9 13.7 12.8 13.6 8.6 11.8 13.3 11.9 15.5 21.3 5.5 14.7 11.9 23.2 31.2 18.3 26.3 24.9 23.4 42.5 16.6 34.9 36.7 AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104361-44114562 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease mutation, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 177.1" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;BJ: 46.1;BJ hTERT+: 30.4;fHDF/TERT166: 49.4;WM-115: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "plasmacytoid DC: 10.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" 2300000 Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: , HPA063595: , HPA064970: " "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavourable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavourable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" 46.5 19.0 8.9 23.9 9.5 3.1 90.9 1.7 5.4 78.1 20.5 17.9 15.8 5.8 73.7 39.4 20.7 43.7 47.9 35.4 12.7 6.4 19.6 6.3 35.5 13.0 12.5 10.8 84.8 8.8 2.7 10.9 26.7 17.2 46.1 7.9 33.3 11.9 70.2 11.4 19.7 16.9 42.6 43.7 16.6 17.6 30.6 9.6 48.0 19.6 12.3 7.5 58.2 177.1 2.3 10.5 0.0 0.0 0.2 1.4 0.4 0.1 0.0 10.8 0.0 35.0 12.4 0.2 46.1 30.4 5.2 1.1 0.0 0.0 1.2 5.1 49.4 0.0 0.5 0.8 2.2 0.1 0.0 3.1 0.0 0.0 9.8 0.0 0.0 18.8 0.0 17.7 0.0 2.3 1.9 0.0 0.0 0.0 19.9 3.7 4.6 0.0 16.6 0.4 0.3 1.2 0.0 1.1 6.1 0.0 0.0 20.2 0.1 3.3 8.1 0.0 21.4 0.1 0.0 0.2 0.2 24.3 0.1 0.0 28.3 0.0 0.0 0.0 0.4 0.0 0.3 2.1 0.4 0.0 0.0 2.3 1.4 0.8 0.0 0.2 0.0 10.5 0.0 0.4 8.9 9.5 1.7 5.4 12.7 6.4 12.5 10.8 17.2 9.6 AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377314 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Supported Mitochondria Mitochondria "HPA004479: AB_1078109, HPA004480: AB_1078108" "unprognostic (1.11e-1)" "unprognostic (7.49e-2)" "unprognostic (1.67e-1)" "prognostic unfavourable (8.68e-4)" "unprognostic (1.31e-1)" "unprognostic (5.06e-3)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (5.35e-2)" "unprognostic (1.54e-2)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "prognostic favourable (6.05e-14)" "unprognostic (5.90e-2)" "unprognostic (9.41e-2)" "unprognostic (5.74e-3)" "unprognostic (2.22e-1)" 11.5 15.8 11.8 14.3 14.0 11.7 19.9 17.2 30.3 11.2 25.7 9.5 12.7 33.1 11.4 10.1 18.3 10.4 11.2 77.4 13.2 13.1 27.2 22.9 16.3 23.7 12.0 13.2 12.0 23.1 34.3 12.6 9.9 16.9 10.8 23.5 12.2 14.9 14.8 61.0 17.5 35.0 15.1 14.0 9.9 16.0 8.9 7.1 10.7 16.9 22.4 13.2 14.0 11.6 10.1 15.8 8.5 12.3 19.9 15.2 8.4 16.9 17.4 12.4 14.0 14.4 15.7 16.6 19.0 19.0 27.3 20.0 26.9 10.5 48.9 21.0 17.3 17.1 31.4 21.9 22.3 11.4 13.4 14.6 19.0 25.1 19.7 55.1 22.0 17.4 24.0 25.8 34.2 19.8 32.9 29.0 13.3 26.9 19.7 16.9 17.3 12.8 22.2 39.3 40.8 23.4 37.8 23.2 16.2 29.9 32.4 26.7 14.9 25.0 15.0 32.5 28.0 30.9 24.8 20.4 23.5 31.4 17.8 21.7 14.9 2.6 11.5 8.5 8.7 12.3 10.7 10.1 10.4 13.7 15.8 7.7 13.3 15.2 0.8 19.9 10.8 8.1 6.4 8.4 11.8 14.0 17.2 30.3 13.2 13.1 12.0 13.2 16.9 7.1 AFMID "DKFZp686F03259, KF" ENSG00000183077 Arylformamidase Q63HM1 17 78187317-78207701 "Enzymes, Predicted intracellular proteins" "Tryptophan catabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 78.7" "Cell line enhanced" "Detected in all" "Hep G2: 61.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 14.5" "Group enriched" "Detected in all" 5 "B-cells: 5.1;dendritic cells: 6.7;monocytes: 14.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023861, HPA026536" Uncertain Approved Mitochondria Mitochondria "HPA023861: AB_1844636, HPA026536: AB_1844637" "unprognostic (3.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.53e-1)" "unprognostic (2.65e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.78e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-3)" "unprognostic (1.53e-2)" "unprognostic (5.78e-2)" "unprognostic (9.59e-3)" "unprognostic (9.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (7.79e-2)" 5.9 3.5 12.1 5.4 17.1 4.6 33.0 27.1 18.3 6.1 7.5 44.8 11.7 8.5 7.5 7.0 7.7 11.3 11.4 9.4 17.3 12.0 39.4 78.7 10.6 5.2 29.7 13.3 15.9 27.7 6.9 4.1 12.4 18.1 10.7 9.2 5.8 24.7 11.8 7.9 15.5 7.1 6.6 27.0 6.2 10.2 6.2 23.9 3.9 6.5 5.6 6.2 6.7 7.4 5.1 6.7 1.7 14.5 1.6 1.1 1.5 6.9 9.9 8.7 7.9 9.8 11.5 4.7 10.0 5.7 7.0 8.5 10.5 5.8 21.8 6.6 7.6 6.0 14.7 8.7 9.9 13.8 11.7 17.5 11.6 61.2 8.6 14.4 9.0 15.4 9.3 8.2 10.7 13.1 17.7 7.6 5.4 6.9 11.0 22.0 7.1 17.0 12.6 8.9 26.0 9.5 6.4 19.3 14.4 8.6 25.9 8.1 7.8 14.0 6.4 10.8 7.1 6.8 7.0 11.7 7.7 22.3 8.9 7.1 2.7 1.1 6.1 0.7 0.7 14.5 1.1 5.1 1.0 1.1 6.7 2.0 0.6 0.6 1.7 1.6 9.3 4.4 0.9 1.5 12.1 17.1 27.1 18.3 17.3 12.0 29.7 13.3 18.1 23.9 AGA ASRG ENSG00000038002 Aspartylglucosaminidase P20933 4 177430770-177442503 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 31.5;Karpas-707: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031415, HPA031417" Enhanced "Intracellular and membrane" 28000000 "HPA031415: AB_10603578, HPA031417: AB_10670967" "unprognostic (8.76e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-3)" "unprognostic (2.11e-3)" "unprognostic (2.70e-2)" "prognostic unfavourable (8.61e-4)" "prognostic unfavourable (1.99e-4)" "unprognostic (3.79e-1)" "unprognostic (6.44e-2)" "unprognostic (4.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.09e-1)" "unprognostic (7.49e-2)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (7.42e-2)" "unprognostic (1.47e-2)" 12.8 15.1 11.2 11.2 11.9 10.9 18.5 4.4 13.7 13.5 12.1 24.2 8.0 8.0 9.8 26.4 18.8 7.1 15.1 8.4 13.0 9.4 20.5 26.5 12.4 12.3 14.0 11.0 10.2 14.7 19.2 9.0 9.3 15.0 10.1 11.1 24.0 27.1 10.8 6.7 16.9 14.4 8.1 22.3 14.9 13.0 13.3 10.0 13.4 14.0 14.3 18.3 9.0 10.2 10.0 11.1 16.3 23.8 8.9 16.3 10.3 2.0 4.6 5.3 7.6 6.3 5.6 3.6 15.5 31.5 8.0 10.2 2.4 10.3 10.3 2.9 11.9 2.5 4.5 5.1 16.3 6.6 2.9 4.3 5.1 6.7 4.1 7.5 3.0 4.0 8.9 5.9 2.7 7.6 3.8 44.6 3.3 5.7 6.0 4.7 2.0 4.8 1.9 2.2 1.5 8.5 5.2 2.9 6.7 4.6 4.0 12.3 9.1 15.4 2.3 5.6 5.0 2.6 5.9 8.6 6.6 5.5 9.0 8.5 6.2 15.0 10.7 16.3 11.7 18.9 13.4 10.0 12.8 14.0 10.5 8.1 11.4 16.3 2.4 8.9 23.8 11.1 12.0 10.3 11.2 11.9 4.4 13.7 13.0 9.4 14.0 11.0 15.0 10.0 AGBL2 "CCP2, FLJ23598" ENSG00000165923 "ATP/GTP binding protein like 2" Q5U5Z8 11 47659591-47715389 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 6.0;T-47d: 3.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007718 Uncertain "HPA007718: AB_1078110" "unprognostic (3.44e-5)" "unprognostic (1.16e-1)" "unprognostic (5.84e-2)" "unprognostic (5.33e-4)" "unprognostic (1.13e-1)" "unprognostic (3.00e-1)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (9.83e-3)" "unprognostic (4.11e-2)" "unprognostic (5.56e-2)" "unprognostic (1.79e-1)" "unprognostic (8.24e-6)" "unprognostic (1.01e-2)" "unprognostic (1.28e-1)" "unprognostic (9.62e-2)" "unprognostic (1.17e-3)" 0.4 1.7 0.8 6.6 2.7 0.7 1.1 3.6 1.1 1.9 2.0 2.8 1.5 1.1 1.6 11.2 0.5 12.2 2.4 0.4 1.3 1.4 1.8 3.0 6.4 1.4 0.3 0.3 2.1 4.7 1.2 3.8 0.7 3.4 1.6 0.8 0.7 1.1 1.7 0.4 0.6 3.3 0.6 0.7 1.7 0.8 34.0 0.7 4.4 1.9 0.5 2.6 2.1 1.4 2.6 1.5 0.4 0.2 1.4 2.2 0.6 1.2 0.0 0.0 0.0 0.3 1.7 0.1 0.4 0.8 0.5 1.7 0.6 6.0 0.1 0.4 0.4 1.6 0.0 0.1 0.8 1.8 0.4 0.3 2.9 2.2 0.9 0.0 1.0 1.8 0.7 0.9 0.5 0.1 0.4 1.3 0.9 2.3 1.2 0.6 0.0 0.1 1.7 0.1 0.5 0.9 2.7 2.2 0.5 0.7 0.0 0.7 3.5 0.0 0.2 0.2 0.4 0.3 0.0 0.0 0.1 0.1 0.3 0.3 0.3 0.0 0.1 0.0 1.5 0.0 1.3 1.0 1.6 1.2 0.1 2.6 1.9 1.7 0.4 1.4 0.2 1.5 2.2 0.6 0.8 2.7 3.6 1.1 1.3 1.4 0.3 0.3 3.4 0.7 AGBL3 "CCP3, MGC32955" ENSG00000146856 "ATP/GTP binding protein like 3" Q8NEM8 7 134986508-135147963 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 8.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020397, HPA024150" Uncertain Uncertain "Nuclear speckles,Mitochondria,Cytosol" "Nuclear speckles, Mitochondria, Cytosol" "HPA020397: AB_2242453, HPA024150: AB_1844639" "unprognostic (8.84e-2)" "unprognostic (1.49e-2)" "unprognostic (4.72e-2)" "unprognostic (2.18e-1)" "unprognostic (1.47e-1)" "unprognostic (3.39e-3)" "unprognostic (3.32e-3)" "unprognostic (4.18e-2)" "unprognostic (7.15e-4)" "unprognostic (5.00e-3)" "unprognostic (6.10e-4)" "unprognostic (3.16e-2)" "prognostic unfavourable (4.02e-4)" "unprognostic (2.18e-2)" "unprognostic (2.14e-1)" "unprognostic (8.13e-2)" "unprognostic (1.11e-3)" 3.2 2.7 4.2 4.1 8.4 3.8 4.6 8.7 4.5 4.3 2.4 4.4 4.5 1.6 5.5 15.4 2.2 3.6 3.1 2.4 5.0 3.4 5.3 2.6 3.6 4.0 2.7 4.5 6.8 4.5 0.6 9.2 1.9 3.3 3.8 3.0 3.1 4.9 4.3 4.2 4.7 3.7 3.3 2.9 6.5 4.4 18.7 3.7 2.7 5.4 0.8 2.8 3.3 2.5 2.2 1.7 0.5 0.2 2.2 5.0 1.7 2.6 1.4 3.6 0.8 1.0 1.4 2.2 0.7 0.0 0.5 0.8 4.7 3.0 4.3 1.3 0.0 2.8 1.3 0.5 0.0 3.4 8.8 3.6 5.3 4.6 0.0 1.6 0.0 0.2 0.0 2.1 0.0 1.5 2.6 2.5 0.6 2.5 0.9 1.5 3.1 0.3 2.5 0.2 1.2 2.6 0.5 2.1 2.4 0.5 0.0 0.3 1.9 3.5 0.0 0.4 0.9 0.5 1.6 5.3 1.6 1.9 1.8 4.3 4.4 0.0 0.2 0.4 2.4 0.0 1.8 2.1 1.2 2.5 0.5 2.2 2.0 5.0 0.5 2.2 0.1 1.7 1.7 1.7 4.2 8.4 8.7 4.5 5.0 3.4 2.7 4.5 3.3 3.7 AGBL4 "CCP6, FLJ14442" ENSG00000186094 "ATP/GTP binding protein like 4" Q5VU57 1 48532855-50023913 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 20.4;pituitary gland: 31.5" "Cell line enhanced" "Detected in some" "NTERA-2: 3.6;SCLC-21H: 5.2;SH-SY5Y: 2.0;U-937: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" HPA037994 Approved "HPA037994: AB_10673036" "unprognostic (3.06e-2)" "unprognostic (2.76e-1)" "unprognostic (2.58e-2)" "unprognostic (3.31e-4)" "unprognostic (3.42e-4)" "unprognostic (1.72e-1)" "unprognostic (3.86e-3)" "unprognostic (2.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (5.85e-3)" "unprognostic (3.91e-2)" "unprognostic (1.51e-4)" "unprognostic (5.95e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.85e-1)" 1.4 4.5 7.8 0.8 13.6 1.1 1.5 1.3 20.4 1.0 0.8 3.0 0.1 0.7 1.0 4.5 0.9 7.8 1.0 3.7 7.1 7.2 10.2 4.6 1.6 0.8 3.2 11.6 1.3 2.7 3.6 31.5 2.7 6.7 1.0 0.7 4.6 0.8 1.5 0.9 1.5 0.8 0.7 1.5 1.3 1.1 10.7 1.9 0.0 3.4 0.0 0.8 0.7 0.7 0.8 0.5 2.2 0.3 0.6 1.8 0.2 0.0 0.5 0.8 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.3 0.1 0.4 3.6 0.4 0.1 0.1 0.1 0.1 0.3 5.2 2.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 1.4 0.2 0.0 0.2 0.0 0.1 0.1 2.2 0.5 2.2 0.3 0.4 0.3 0.3 1.8 0.5 0.2 0.1 0.2 0.8 0.4 0.2 1.0 0.6 0.2 0.5 0.3 0.2 7.8 13.6 1.3 20.4 7.1 7.2 3.2 11.6 6.7 1.9 AGBL5 "CCP5, FLJ21839" ENSG00000084693 "ATP/GTP binding protein like 5" Q8NDL9 2 27042364-27070622 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "testis: 91.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030981 Uncertain Supported "Microtubules,Cytokinetic bridge,Cytosol" "Cytokinetic bridge" "Microtubules, Cytosol" "HPA030981: AB_10611673" "unprognostic (1.29e-2)" "unprognostic (8.70e-2)" "unprognostic (2.26e-1)" "unprognostic (3.13e-3)" "unprognostic (1.95e-1)" "unprognostic (1.07e-1)" "prognostic unfavourable (6.87e-5)" "unprognostic (1.86e-1)" "unprognostic (4.34e-1)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (3.41e-2)" "unprognostic (5.56e-2)" "unprognostic (2.05e-1)" "unprognostic (1.69e-2)" "unprognostic (4.50e-2)" 3.8 8.1 3.9 3.5 4.8 3.8 4.2 3.1 6.6 5.0 6.8 6.6 11.7 2.8 5.4 9.3 6.3 7.2 6.6 4.1 3.4 3.9 8.2 3.0 3.6 3.2 3.5 3.4 5.9 5.9 11.2 6.2 6.3 5.4 6.8 3.8 7.7 8.2 5.9 2.6 6.8 3.9 8.6 3.4 4.6 5.4 91.6 3.5 8.4 9.9 4.9 4.4 7.8 3.5 5.7 5.4 7.1 2.3 11.2 6.3 4.6 22.8 14.8 24.3 16.2 5.2 10.5 27.2 4.7 10.2 13.6 14.1 12.8 17.5 12.7 14.8 8.1 10.5 19.4 21.2 15.1 10.6 28.8 18.6 18.5 27.6 10.6 8.9 6.3 10.9 16.1 11.9 9.8 14.2 15.9 10.4 13.1 9.0 26.0 13.5 17.2 10.2 26.9 27.5 19.9 13.9 5.8 16.3 23.3 9.2 7.3 15.1 10.9 6.9 6.7 12.7 17.5 6.1 10.0 20.7 10.8 26.0 14.1 10.3 11.3 7.1 2.3 5.7 4.5 1.3 3.4 5.7 5.7 6.3 5.4 3.0 5.1 2.8 1.4 11.2 0.9 3.0 3.6 4.6 3.9 4.8 3.1 6.6 3.4 3.9 3.5 3.4 5.4 3.5 AGK "FLJ10842, MULK" ENSG00000006530 "Acylglycerol kinase" Q53H12 7 141551189-141655244 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Cardiomyopathy, Cataract, Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 37.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020959, HPA053471" Supported Supported Vesicles,Mitochondria "Intracellular and membrane" Mitochondria Vesicles "HPA020959: AB_1854206, HPA053471: " "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.28e-2)" "unprognostic (9.47e-3)" "unprognostic (5.43e-2)" "unprognostic (2.15e-2)" "unprognostic (3.68e-2)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (6.24e-3)" "unprognostic (7.90e-2)" "unprognostic (9.29e-2)" "unprognostic (9.65e-2)" "unprognostic (3.30e-1)" "unprognostic (1.18e-1)" 8.7 12.0 11.9 8.0 19.0 5.9 10.6 21.3 23.7 8.8 8.9 10.2 8.8 6.4 16.8 17.1 9.5 11.9 6.8 24.5 16.1 12.3 16.0 10.5 8.4 10.0 11.8 18.8 10.8 8.0 15.7 13.3 9.9 14.2 10.1 13.4 10.6 13.5 10.7 8.4 6.8 8.8 15.0 13.9 12.2 9.0 12.9 9.0 7.8 9.8 8.4 15.6 8.4 8.5 4.6 6.4 0.4 5.5 37.9 10.3 5.7 12.2 13.3 13.2 10.9 10.5 13.0 9.0 13.0 12.7 20.9 20.9 10.3 9.5 13.8 11.7 12.4 9.1 18.4 15.1 22.5 16.2 16.4 12.8 6.3 10.2 15.6 8.8 6.9 14.4 13.3 18.3 18.0 16.0 19.0 19.7 10.1 12.3 23.9 4.1 14.0 15.0 15.5 2.3 41.2 13.3 10.4 11.6 15.9 13.5 16.3 13.4 8.7 9.7 8.9 9.7 7.6 12.9 18.7 15.0 14.8 6.6 15.9 4.1 26.6 0.0 2.6 0.4 9.1 5.5 6.5 4.6 7.4 10.3 6.4 2.5 5.5 9.6 0.2 37.9 3.2 2.5 7.2 5.7 11.9 19.0 21.3 23.7 16.1 12.3 11.8 18.8 14.2 9.0 AGL ENSG00000162688 "Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase" P35573 1 99850084-99924023 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycogen biosynthesis" "Glycosidase, Glycosyltransferase, Hydrolase, Multifunctional enzyme, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 23.1;skeletal muscle: 85.6;tongue: 34.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028498, HPA054340" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" 16000 Nucleoplasm "Nuclear bodies, Cytosol" "HPA028498: AB_10600975, HPA054340: " "unprognostic (2.90e-1)" "unprognostic (5.34e-2)" "unprognostic (3.99e-3)" "unprognostic (2.18e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "unprognostic (1.12e-1)" "unprognostic (1.92e-2)" "unprognostic (9.37e-3)" "unprognostic (1.11e-1)" "unprognostic (8.10e-3)" "unprognostic (7.61e-2)" "prognostic favourable (1.73e-10)" "unprognostic (6.38e-2)" "unprognostic (2.89e-1)" "unprognostic (1.15e-1)" "unprognostic (7.13e-2)" 5.0 4.5 2.5 4.7 3.6 2.0 4.2 5.4 6.1 3.4 4.5 2.1 5.4 3.3 4.8 4.2 9.1 4.1 2.6 8.2 2.2 2.3 5.8 23.1 4.2 5.3 2.4 4.2 3.8 3.6 8.7 4.7 4.8 2.9 5.5 4.2 3.9 5.1 8.7 85.6 3.7 4.0 5.4 2.8 4.8 4.4 2.9 1.2 7.1 4.3 34.4 3.4 6.7 3.6 3.0 2.3 3.5 1.6 6.1 4.3 2.1 11.8 3.5 4.2 6.9 7.0 6.6 14.2 3.8 5.6 3.3 5.9 13.3 4.0 15.6 7.3 6.4 6.7 24.6 7.4 6.3 8.3 7.8 9.1 12.2 7.4 4.6 8.0 5.5 8.1 4.8 4.6 3.9 5.2 14.9 1.1 3.4 3.7 9.4 2.5 6.7 4.6 0.0 1.4 0.8 10.1 16.1 10.5 7.3 10.9 10.5 5.8 7.5 5.4 5.3 4.0 5.8 5.4 3.7 4.5 3.5 18.1 7.1 2.1 2.1 0.1 1.3 3.5 4.3 1.6 4.1 3.0 3.2 2.9 2.3 2.9 3.2 3.2 1.5 6.1 0.9 2.1 3.3 2.1 2.5 3.6 5.4 6.1 2.2 2.3 2.4 4.2 2.9 1.2 AGMAT FLJ23384 ENSG00000116771 Agmatinase Q9BSE5 1 15572353-15585110 "Enzymes, Predicted intracellular proteins" "Putrescine biosynthesis, Spermidine biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3;kidney: 54.7;liver: 66.1" "Cell line enhanced" "Detected in many" "CACO-2: 18.6;Hep G2: 45.0;RPMI-8226: 11.2" "Group enriched" "Detected in all" 5 "colorectal cancer: 18.5;liver cancer: 25.3;renal cancer: 11.2;stomach cancer: 11.1" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 4.6;T-cells: 10.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA026443, HPA028321" Enhanced 250000 "HPA026443: AB_1844644, HPA028321: AB_10600779" "unprognostic (2.27e-2)" "unprognostic (3.45e-1)" "unprognostic (1.79e-3)" "unprognostic (3.60e-2)" "unprognostic (8.72e-2)" "unprognostic (6.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-2)" "unprognostic (2.06e-2)" "unprognostic (2.37e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-1)" "prognostic favourable (5.13e-4)" "unprognostic (4.43e-3)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (2.45e-2)" 0.7 0.8 0.7 2.8 0.5 0.1 0.4 0.2 1.0 0.2 14.9 0.3 0.0 7.1 0.3 1.2 0.5 0.2 3.6 0.3 0.6 0.8 54.7 66.1 0.2 1.3 0.7 0.3 0.2 1.1 1.3 0.4 0.2 0.6 0.3 2.8 0.1 9.6 0.0 12.3 0.2 21.3 0.1 0.3 1.0 0.5 0.5 0.1 1.0 0.3 1.7 1.5 0.4 0.2 4.6 0.4 1.4 0.3 0.4 10.5 2.8 3.9 3.2 0.2 0.1 0.0 0.4 0.1 0.7 0.7 0.4 0.2 18.6 2.6 0.0 0.1 0.5 0.0 0.0 0.0 0.5 3.8 0.0 2.4 2.6 45.0 0.5 1.9 0.0 0.5 0.2 1.3 0.0 0.4 0.0 5.3 1.0 4.2 0.0 1.8 4.2 1.8 0.0 0.0 11.2 0.1 1.0 0.7 0.5 5.4 0.2 0.6 0.7 3.8 0.4 0.1 0.1 1.0 0.0 0.1 3.0 2.5 0.2 0.0 0.0 0.9 0.3 0.2 2.4 0.3 3.1 4.6 5.7 3.0 0.2 3.2 10.5 5.9 1.4 0.4 0.2 0.4 7.1 2.8 0.7 0.5 0.2 1.0 0.6 0.8 0.7 0.3 0.6 0.1 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200318-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 41.9;liver: 57.9" "Cell line enhanced" "Detected in some" "HSkMC: 4.0;Karpas-707: 8.5;NTERA-2: 3.8;SCLC-21H: 3.6;TIME: 4.3;WM-115: 16.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 3.6;neutrophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA057900 Uncertain Vesicles Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 6.8 0.2 0.8 1.0 1.2 0.1 3.7 0.3 0.5 0.3 16.5 1.1 0.1 4.6 0.3 7.3 0.3 0.3 4.7 0.9 0.7 0.6 5.3 57.9 0.4 0.5 1.1 0.8 0.3 0.3 0.0 0.7 0.4 0.7 0.4 0.3 0.0 0.4 0.1 0.5 0.5 41.9 0.1 1.1 0.3 0.3 1.8 2.0 0.0 0.7 0.1 0.1 1.0 0.4 0.2 0.1 3.6 0.1 0.6 0.1 0.0 0.0 2.4 0.0 2.1 0.2 3.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 1.2 0.0 0.7 3.6 0.0 0.0 0.0 0.0 0.0 0.0 4.3 1.5 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 16.8 3.6 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 3.1 0.6 0.0 0.1 0.0 0.0 0.8 1.2 0.3 0.4 0.7 0.6 1.1 0.8 0.7 2.0 AGO2 "CASC7, EIF2C2, hAGO2, LINC00980, Q10" ENSG00000123908 "Argonaute 2, RISC catalytic component" Q9UKV8 8 140520156-140635619 "Enzymes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Endonuclease, Hydrolase, Nuclease, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019309, HPA058075" Approved Supported "Nucleoplasm,Cell Junctions" 35000000 "Nucleoplasm, Cell Junctions" "CAB019309: , HPA058075: " "unprognostic (2.75e-2)" "unprognostic (1.79e-3)" "unprognostic (1.27e-1)" "prognostic unfavourable (1.21e-4)" "unprognostic (2.46e-1)" "unprognostic (2.15e-1)" "unprognostic (1.49e-3)" "unprognostic (8.86e-2)" "unprognostic (2.21e-1)" "unprognostic (8.50e-2)" "unprognostic (3.47e-2)" "unprognostic (2.73e-1)" "prognostic unfavourable (1.82e-5)" "unprognostic (1.32e-1)" "unprognostic (2.77e-1)" "unprognostic (1.32e-1)" "unprognostic (3.02e-1)" 11.2 6.6 7.7 9.9 13.1 16.2 25.0 9.9 11.4 7.5 9.2 12.1 12.8 5.3 10.2 10.4 10.6 8.6 8.8 12.4 8.8 5.3 6.9 7.4 13.2 12.5 13.4 5.0 11.8 8.4 13.2 8.8 9.9 10.7 7.5 6.9 5.6 8.1 12.6 37.1 14.1 7.5 15.0 11.7 6.9 10.0 5.9 12.7 11.1 8.6 8.2 8.9 10.4 18.4 2.5 2.1 6.4 2.6 2.4 3.0 1.5 12.6 10.5 10.8 12.3 7.1 8.4 9.1 8.0 5.8 3.6 4.5 11.6 3.8 14.6 10.1 7.7 8.6 18.2 8.6 8.0 8.2 9.5 17.1 18.0 7.4 6.4 7.0 5.8 5.7 7.8 10.0 10.4 8.3 17.8 9.2 11.7 19.2 12.1 5.6 8.0 18.3 12.5 9.1 6.6 4.6 13.2 12.7 9.2 12.5 4.3 8.9 11.0 10.3 11.6 6.3 17.5 9.8 12.8 8.2 2.6 10.3 4.6 12.8 9.2 1.8 2.6 0.7 2.7 2.3 3.0 1.3 2.6 2.3 2.1 2.5 2.7 2.7 6.4 2.4 2.3 1.5 2.1 1.5 7.7 13.1 9.9 11.4 8.8 5.3 13.4 5.0 10.7 12.7 AGPAT1 LPAAT-alpha ENSG00000204310 "1-acylglycerol-3-phosphate O-acyltransferase 1" Q99943 6 32168212-32178096 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 35.4;fHDF/TERT166: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048478, HPA073355" Approved Supported "Endoplasmic reticulum,Rods & Rings" "Endoplasmic reticulum" "Rods & Rings" "HPA048478: , HPA073355: " "prognostic unfavourable (1.93e-4)" "unprognostic (9.35e-3)" "unprognostic (1.87e-3)" "prognostic unfavourable (5.21e-4)" "unprognostic (4.79e-2)" "unprognostic (7.05e-2)" "unprognostic (7.16e-3)" "unprognostic (1.55e-1)" "unprognostic (3.79e-1)" "unprognostic (4.24e-3)" "unprognostic (1.84e-3)" "unprognostic (1.77e-1)" "unprognostic (6.58e-2)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (9.92e-3)" "unprognostic (7.00e-2)" 11.7 32.3 21.5 8.3 33.1 7.4 12.1 18.7 32.4 26.9 22.1 19.6 19.6 32.0 25.1 53.3 13.8 26.9 22.3 19.4 22.8 21.1 26.4 20.3 24.3 10.7 20.3 23.6 33.1 18.5 1.3 16.6 18.5 22.4 18.5 24.8 17.5 17.4 19.5 25.5 9.1 46.9 17.9 18.6 11.7 27.8 27.7 17.4 12.1 33.4 9.0 14.6 19.3 12.7 6.7 13.8 13.2 9.6 8.9 10.1 5.7 0.0 0.1 13.5 0.0 35.4 23.9 12.6 0.0 0.0 0.0 0.0 27.6 0.0 0.0 11.6 33.8 3.3 29.1 9.6 0.0 0.0 22.6 0.0 0.0 29.0 0.0 0.0 27.4 13.3 12.5 0.0 12.6 8.2 17.4 17.8 29.3 7.3 0.0 6.3 0.0 4.2 0.1 0.0 0.1 8.8 0.0 0.0 0.0 13.4 4.3 15.1 16.9 0.0 5.8 0.0 5.0 0.0 0.0 10.7 10.1 4.4 17.4 0.0 0.0 2.7 5.7 13.2 9.2 9.6 8.7 6.7 5.8 10.1 10.3 5.9 5.0 7.3 11.0 8.9 6.6 13.8 7.8 5.7 21.5 33.1 18.7 32.4 22.8 21.1 20.3 23.6 22.4 17.4 AGPAT2 "BSCL, LPAAT-beta" ENSG00000169692 "1-acylglycerol-3-phosphate O-acyltransferase 2" O15120 9 136673143-136687423 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 71.5;liver: 63.1" "Cell line enhanced" "Detected in many" "HDLM-2: 50.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA019544 Uncertain Approved Centrosome Centrosome "HPA019544: AB_1844646" "unprognostic (3.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (9.30e-3)" "unprognostic (5.06e-3)" "unprognostic (8.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (2.17e-1)" "unprognostic (5.61e-2)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-2)" "unprognostic (2.93e-1)" 71.5 5.3 2.3 8.1 2.2 8.4 35.2 2.0 3.0 7.4 20.2 2.2 5.9 31.3 4.7 7.1 11.7 4.1 15.8 12.4 2.8 2.4 10.9 63.1 12.1 11.1 2.5 2.8 5.3 47.7 2.5 6.2 4.9 2.6 5.5 3.3 8.9 12.9 6.2 9.5 7.0 33.6 4.0 1.9 6.8 11.0 5.2 1.9 5.1 13.4 7.0 8.8 6.6 4.9 7.0 20.3 33.2 28.4 2.1 2.5 9.8 14.6 20.6 2.4 11.4 17.7 5.5 10.4 9.7 7.7 6.7 5.1 23.3 29.0 4.8 21.9 5.5 39.7 3.4 6.0 0.7 50.0 15.8 7.1 8.5 5.1 12.2 7.5 17.5 5.3 8.4 5.7 3.0 3.4 8.6 0.8 2.8 26.4 0.5 23.3 6.2 37.5 10.9 8.8 26.6 7.8 9.3 5.5 8.8 12.6 13.3 15.9 8.4 29.5 6.8 8.9 9.1 2.8 6.2 1.2 0.1 3.1 0.1 16.1 8.8 6.0 28.4 33.2 2.2 25.3 2.1 4.1 1.9 2.5 14.9 7.0 1.6 1.8 19.1 2.1 22.2 20.3 2.3 9.8 2.3 2.2 2.0 3.0 2.8 2.4 2.5 2.8 2.6 1.9 AGPAT4 "dJ473J16.2, LPAAT-delta" ENSG00000026652 "1-acylglycerol-3-phosphate O-acyltransferase 4" Q9NRZ5 6 161129979-161274061 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.0" "Cell line enhanced" "Detected in many" "AF22: 19.8;HEL: 14.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053287, HPA060525" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" "Golgi apparatus" "Nucleoli, Vesicles" "HPA053287: , HPA060525: " "unprognostic (5.69e-2)" "prognostic unfavourable (1.45e-4)" "unprognostic (1.73e-1)" "unprognostic (3.43e-2)" "unprognostic (4.14e-2)" "unprognostic (6.67e-3)" "unprognostic (1.94e-4)" "unprognostic (1.05e-1)" "unprognostic (3.42e-2)" "unprognostic (2.77e-2)" "unprognostic (1.76e-3)" "unprognostic (1.67e-1)" "prognostic unfavourable (4.08e-4)" "unprognostic (1.82e-2)" "unprognostic (8.87e-2)" "unprognostic (3.63e-4)" "unprognostic (5.51e-2)" 5.6 4.2 10.5 3.5 19.1 8.0 4.5 9.6 26.6 5.3 4.2 35.6 1.0 2.6 10.7 4.5 5.2 7.2 8.0 2.9 14.2 11.8 5.2 2.0 6.1 2.0 25.8 12.4 10.0 2.3 1.3 9.8 14.6 27.4 3.7 4.4 0.7 2.7 4.9 2.1 1.9 2.5 8.5 49.0 5.2 3.0 4.2 19.8 0.6 4.8 2.0 2.2 4.0 3.8 1.1 1.9 0.6 3.5 5.8 7.0 2.1 0.3 0.8 19.8 3.9 3.7 7.6 0.8 0.7 0.2 1.5 2.5 1.1 3.5 0.5 1.4 3.1 0.3 3.6 3.0 1.4 2.2 6.2 14.8 3.5 0.0 2.9 0.1 2.1 9.1 1.5 4.0 2.1 4.6 7.3 6.8 1.8 0.0 1.0 1.6 4.7 7.6 0.0 0.9 0.4 4.3 0.3 11.5 4.4 3.0 1.6 0.8 0.8 1.0 5.1 2.1 2.6 1.4 3.3 0.5 0.7 0.0 7.8 0.8 1.3 0.0 3.5 0.0 7.0 2.8 2.3 0.4 3.3 4.1 1.9 1.1 1.7 2.7 0.6 5.8 2.5 1.5 2.9 2.1 10.5 19.1 9.6 15.8 14.2 11.8 25.8 12.4 27.4 19.8 AGPAT5 "FLJ11210, LPAAT-e, LPAAT-epsilon" ENSG00000155189 "1-acylglycerol-3-phosphate O-acyltransferase 5" Q9NUQ2 8 6708357-6759666 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010644, HPA010950, HPA011646" Approved Supported Mitochondria Mitochondria "HPA010644: AB_1844647, HPA010950: AB_1844648, HPA011646: " "unprognostic (1.05e-3)" "unprognostic (4.69e-1)" "prognostic favourable (8.82e-4)" "unprognostic (2.05e-2)" "unprognostic (2.99e-1)" "unprognostic (1.44e-2)" "prognostic unfavourable (4.57e-4)" "unprognostic (4.92e-1)" "unprognostic (1.82e-1)" "unprognostic (2.98e-2)" "unprognostic (6.33e-2)" "unprognostic (2.91e-1)" "unprognostic (6.62e-2)" "unprognostic (2.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (5.09e-3)" 5.9 12.5 20.0 8.5 20.7 5.1 9.8 10.0 21.2 6.0 12.2 16.5 6.8 9.3 9.3 19.1 8.4 9.7 5.9 4.0 19.3 16.9 14.2 14.3 5.1 16.8 18.7 9.5 6.4 16.2 11.4 18.5 16.3 14.2 11.0 12.3 3.3 5.4 16.0 10.2 5.1 8.4 8.6 30.6 8.6 11.0 30.8 12.7 14.3 7.3 6.8 10.4 7.3 5.7 11.0 8.4 3.0 4.8 5.3 3.9 2.9 9.2 7.4 11.7 6.9 3.1 5.0 10.4 4.9 5.1 7.4 7.1 4.6 7.3 20.2 3.3 3.2 11.0 8.9 9.9 12.9 4.4 6.1 24.9 5.8 10.4 7.8 10.4 10.9 6.6 8.4 7.2 9.6 12.8 18.4 10.9 12.1 6.0 18.8 12.8 20.4 5.8 13.6 14.1 7.9 6.7 13.1 23.9 12.5 4.7 8.7 9.3 3.9 13.7 5.3 12.0 5.7 4.6 13.6 4.1 12.6 11.0 7.1 12.6 14.3 3.0 4.1 2.6 1.9 4.8 3.9 8.7 3.0 3.3 2.7 11.0 2.3 2.7 0.4 5.3 4.2 8.4 2.7 2.9 20.0 20.7 10.0 14.6 19.3 16.9 18.7 9.5 14.2 12.7 AGPS "ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY" ENSG00000018510 "Alkylglycerone phosphate synthase" O00116 2 177392644-177559299 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cataract, Disease mutation, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030209, HPA030210, HPA030211" Supported Enhanced Peroxisomes "Intracellular and membrane" 9300 Peroxisomes "HPA030209: AB_10600634, HPA030210: AB_10600202, HPA030211: AB_10602195" "unprognostic (7.10e-2)" "unprognostic (1.20e-2)" "unprognostic (1.76e-3)" "unprognostic (3.79e-2)" "unprognostic (8.34e-2)" "unprognostic (3.78e-2)" "prognostic unfavourable (8.62e-6)" "unprognostic (1.23e-2)" "unprognostic (7.23e-2)" "unprognostic (5.41e-2)" "prognostic unfavourable (8.35e-4)" "unprognostic (7.74e-2)" "prognostic favourable (9.45e-4)" "unprognostic (7.18e-2)" "unprognostic (3.46e-1)" "unprognostic (4.94e-3)" "unprognostic (1.92e-2)" 22.9 17.7 13.5 21.2 14.9 28.3 17.1 14.9 13.4 16.0 23.5 17.2 14.1 14.1 22.4 10.5 18.4 12.5 16.0 23.9 14.2 13.5 20.8 21.2 15.2 14.7 17.4 11.8 16.4 21.2 37.0 11.7 14.7 15.0 14.7 24.0 8.0 18.2 10.8 23.2 9.6 17.6 21.3 31.8 17.1 14.5 19.1 13.7 29.5 14.2 14.4 14.5 16.9 20.7 3.4 7.6 11.2 6.8 5.6 6.4 3.0 17.7 11.4 8.1 8.3 10.4 11.4 19.3 13.9 6.9 11.9 11.8 21.2 12.4 20.0 30.4 14.4 19.4 21.8 14.2 15.6 26.4 7.4 27.8 19.8 24.9 10.6 30.1 29.6 9.9 9.0 19.1 15.2 23.8 19.0 12.5 14.3 0.0 24.3 10.2 13.8 18.9 19.5 24.2 12.1 20.3 21.3 10.0 12.1 26.4 2.3 16.4 0.1 12.5 24.4 10.7 36.7 10.9 24.3 16.2 28.0 10.0 9.8 13.5 4.1 3.8 6.1 11.2 4.3 6.7 6.4 3.4 5.5 5.3 7.6 2.1 5.3 3.1 1.3 5.6 6.8 0.7 6.2 3.0 13.5 14.9 14.9 13.4 14.2 13.5 17.4 11.8 15.0 13.7 AGTPBP1 "CCP1, KIAA1035, Nna1" ENSG00000135049 "ATP/GTP binding protein 1" Q9UPW5 9 85546539-85742029 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057208 Approved Approved Nucleoli,Vesicles "Nucleoli, Vesicles" "HPA057208: " "unprognostic (2.15e-1)" "unprognostic (3.78e-2)" "unprognostic (4.93e-3)" "unprognostic (6.12e-2)" "unprognostic (1.42e-1)" "unprognostic (8.95e-3)" "unprognostic (1.86e-2)" "unprognostic (1.65e-1)" "unprognostic (1.71e-1)" "unprognostic (8.26e-3)" "unprognostic (5.69e-3)" "unprognostic (6.31e-2)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-1)" "unprognostic (9.60e-3)" "unprognostic (1.25e-1)" 7.9 5.7 13.1 8.6 14.6 48.2 6.0 14.2 21.4 5.1 5.0 21.6 1.8 3.8 5.0 4.2 5.4 4.2 5.3 11.2 17.3 13.5 6.8 4.5 11.9 16.0 18.8 14.5 3.5 6.4 8.0 4.8 6.0 23.5 4.9 5.9 7.4 3.9 3.4 13.6 6.0 4.3 6.4 24.1 12.8 5.3 12.5 14.4 8.8 5.8 4.3 7.8 5.7 3.8 1.6 10.7 20.3 9.5 4.5 6.6 5.7 2.9 5.7 16.8 6.7 3.5 3.8 6.4 4.4 3.8 4.5 5.1 3.0 5.1 18.3 3.7 4.5 1.7 7.8 5.6 4.3 19.4 6.9 3.1 6.9 5.4 7.3 14.1 3.7 3.5 6.6 4.2 14.5 7.2 3.9 14.7 2.0 4.6 10.9 8.4 11.7 4.0 10.0 6.2 5.6 7.8 3.2 20.4 14.5 5.0 5.5 9.1 2.1 4.6 7.1 2.9 5.2 18.5 5.2 10.1 8.4 8.4 6.2 13.9 5.9 20.3 9.5 8.3 6.6 5.7 6.4 1.6 3.3 5.1 10.7 1.2 2.7 5.2 14.0 4.5 4.3 1.7 3.4 5.7 13.1 14.6 14.2 21.4 17.3 13.5 18.8 14.5 23.5 14.4 AGXT "AGT, AGT1, AGXT1, PH1, SPAT, SPT" ENSG00000172482 "Alanine-glyoxylate aminotransferase" P21549 2 240868479-240880502 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 172 "liver: 247.3" "Cell line enriched" "Detected in some" 5 "Hep G2: 13.1" "Cancer enriched" "Detected in some" 425 "liver cancer: 253.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035370, HPA035371" Enhanced Supported Vesicles 5200000 Vesicles "HPA035370: AB_10673218, HPA035371: AB_2674593" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (3.37e-4)" "unprognostic (1.04e-1)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "prognostic favourable (5.92e-5)" "unprognostic (8.28e-2)" "unprognostic (2.77e-1)" "unprognostic (5.39e-2)" "unprognostic (1.55e-1)" "unprognostic (7.57e-3)" "unprognostic (2.54e-1)" "unprognostic (9.22e-2)" "unprognostic (1.37e-1)" "unprognostic (3.26e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 247.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 13.1 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.2 0.0 0.0 0.0 0.1 0.0 0.8 2.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 AGXT2 AGT2 ENSG00000113492 "Alanine--glyoxylate aminotransferase 2" Q9BYV1 5 34998101-35048135 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "kidney: 63.2;liver: 63.3" "Cell line enriched" "Detected in single" 11 "T-47d: 3.5" "Group enriched" "Detected in some" 112 "liver cancer: 9.2;renal cancer: 12.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037382 Enhanced 7300 "HPA037382: AB_10670851" "unprognostic (2.61e-1)" "unprognostic (1.40e-2)" "prognostic favourable (7.47e-4)" "unprognostic (8.24e-2)" "unprognostic (1.28e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.9 0.0 0.0 0.0 63.2 63.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AHCY SAHH ENSG00000101444 Adenosylhomocysteinase P23526 20 34280268-34311802 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA041225, HPA044675" Approved Supported Cytosol 3900000 Cytosol "HPA041225: AB_2677371, HPA044675: AB_2679041" "unprognostic (3.35e-1)" "unprognostic (2.17e-1)" "unprognostic (2.41e-2)" "unprognostic (1.32e-2)" "unprognostic (7.74e-2)" "unprognostic (3.15e-2)" "unprognostic (7.34e-3)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (2.61e-1)" "unprognostic (4.21e-2)" "unprognostic (1.24e-1)" "unprognostic (5.27e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.88e-1)" "unprognostic (2.93e-3)" 15.3 18.6 11.7 15.4 15.0 17.0 24.3 6.3 16.4 25.1 30.0 14.7 18.4 24.6 20.2 23.9 43.4 26.6 22.4 26.0 12.0 12.8 52.2 99.8 19.1 18.1 16.0 10.6 39.1 72.0 15.7 15.0 44.5 13.2 26.9 20.2 14.4 32.4 18.3 48.2 14.8 20.4 18.8 15.7 17.9 22.2 33.3 13.4 25.0 52.8 31.0 29.2 18.2 20.5 9.1 24.1 2.3 26.0 4.6 7.4 11.4 36.8 48.4 20.5 36.2 24.0 25.8 23.6 15.2 21.8 33.9 27.0 130.7 31.9 57.5 27.1 19.4 42.4 48.3 85.2 21.8 7.6 29.3 69.4 24.1 84.1 25.8 32.3 22.8 53.4 38.8 21.0 33.9 23.1 33.7 14.6 17.9 39.1 42.2 30.6 26.3 47.2 31.7 52.2 40.4 30.3 26.3 35.6 23.7 30.3 36.0 50.4 54.1 30.1 14.6 29.5 31.4 14.8 28.6 21.8 31.9 34.6 21.7 20.0 15.7 2.3 13.7 0.4 4.1 26.0 6.7 9.1 6.0 5.3 21.1 7.8 6.6 7.4 1.1 4.6 16.5 24.1 6.7 11.4 11.7 15.0 6.3 16.4 12.0 12.8 16.0 10.6 13.2 13.4 AHCYL2 KIAA0828 ENSG00000158467 "Adenosylhomocysteinase like 2" Q96HN2 7 129225023-129430211 "Enzymes, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 72.4" "Cell line enriched" "Detected in all" 8 "HDLM-2: 71.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053128 Uncertain Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA053128: AB_2682050" "unprognostic (1.57e-1)" "unprognostic (2.91e-1)" "unprognostic (8.52e-3)" "unprognostic (1.71e-3)" "unprognostic (7.44e-3)" "prognostic favourable (4.17e-4)" "unprognostic (8.85e-2)" "unprognostic (1.43e-1)" "unprognostic (3.35e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-1)" "unprognostic (6.79e-3)" "prognostic favourable (1.08e-7)" "unprognostic (4.70e-3)" "unprognostic (2.46e-1)" "unprognostic (7.21e-2)" "unprognostic (2.62e-1)" 4.3 6.6 12.8 5.9 20.3 1.5 4.3 7.2 16.9 7.1 61.8 13.3 5.1 23.1 6.1 3.3 5.7 4.4 22.7 3.4 16.5 9.6 11.9 3.4 26.1 4.2 10.7 14.9 5.7 5.8 9.1 12.8 5.1 19.8 5.0 72.4 24.3 15.0 3.3 20.7 9.8 15.0 5.3 11.4 2.9 16.5 8.1 9.6 4.6 24.1 4.0 4.0 5.4 4.7 0.9 1.3 2.0 2.5 3.3 5.0 0.5 2.6 4.2 8.1 4.8 2.2 3.2 1.7 2.1 2.9 2.4 2.1 2.4 1.8 1.6 2.2 2.3 1.8 4.0 3.3 2.7 71.8 5.0 3.8 4.6 1.9 1.3 2.8 4.9 3.0 4.3 1.9 2.9 4.7 1.7 9.1 3.1 2.5 4.1 3.6 4.0 3.0 2.7 2.2 4.3 4.8 3.5 3.7 2.3 4.8 2.0 2.8 1.9 2.0 2.7 2.0 1.2 5.4 2.2 3.8 4.3 2.2 5.3 3.0 3.1 0.1 1.2 2.0 0.9 2.5 1.2 0.9 1.5 0.7 1.3 0.5 1.3 0.5 0.4 3.3 1.2 0.4 5.0 0.5 12.8 20.3 7.2 16.9 16.5 9.6 10.7 14.9 19.8 9.6 AK1 ENSG00000106992 "Adenylate kinase 1" P00568 9 127866480-127877743 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 84.5;skeletal muscle: 279.0" "Cell line enhanced" "Detected in many" "U-2197: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006456, CAB009893" Enhanced Supported Cytosol 32000000 Cytosol "CAB009893: AB_2225151, HPA006456: AB_1078116" "unprognostic (6.07e-3)" "unprognostic (1.44e-2)" "unprognostic (2.36e-2)" "unprognostic (1.03e-1)" "unprognostic (3.44e-1)" "unprognostic (3.09e-1)" "unprognostic (1.52e-2)" "unprognostic (3.12e-2)" "unprognostic (2.19e-1)" "unprognostic (5.74e-2)" "unprognostic (6.65e-3)" "unprognostic (2.07e-1)" "unprognostic (1.81e-2)" "prognostic favourable (7.31e-4)" "unprognostic (2.62e-1)" "unprognostic (8.40e-3)" "unprognostic (6.99e-3)" 7.7 9.2 19.6 3.7 18.8 6.5 3.9 9.8 17.3 10.5 8.6 18.1 12.2 5.2 3.4 17.3 9.0 84.5 12.0 60.4 17.6 18.5 6.3 10.7 18.7 2.2 16.4 15.3 12.3 4.6 5.6 7.1 2.9 17.5 5.2 10.8 7.0 13.4 15.7 279.0 3.4 2.6 6.3 11.5 5.6 5.8 9.8 11.1 0.0 10.5 61.5 4.0 4.4 4.4 1.2 3.4 2.8 0.4 1.4 1.5 1.2 15.2 6.6 8.4 11.5 20.5 41.8 7.7 10.6 10.7 18.9 11.5 4.8 9.7 0.4 11.6 21.8 22.0 0.0 11.8 7.6 2.4 7.3 2.2 18.9 8.4 11.5 0.0 0.3 31.7 23.0 14.0 10.2 25.2 8.9 0.6 21.4 14.5 0.0 0.3 3.0 20.4 0.4 8.5 3.3 12.6 1.1 13.7 8.5 28.0 16.1 8.1 12.9 9.1 20.8 13.2 5.4 46.5 10.1 1.0 0.1 0.0 16.6 0.0 9.2 0.9 0.4 0.4 1.5 0.3 1.1 0.3 0.6 1.1 0.1 1.2 0.3 1.1 2.8 1.4 0.4 3.4 0.3 1.2 19.6 18.8 9.8 17.3 17.6 18.5 16.4 15.3 17.5 11.1 AK2 ENSG00000004455 "Adenylate kinase 2" P54819 1 33007940-33080996 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation, SCID" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018479 Approved 5500000 "HPA018479: AB_1844676" "prognostic favourable (4.37e-4)" "unprognostic (3.25e-2)" "unprognostic (2.80e-2)" "prognostic unfavourable (8.65e-4)" "unprognostic (3.16e-2)" "unprognostic (8.21e-2)" "prognostic unfavourable (9.32e-4)" "unprognostic (7.86e-3)" "unprognostic (1.85e-2)" "unprognostic (1.28e-1)" "prognostic unfavourable (6.40e-4)" "unprognostic (4.95e-2)" "unprognostic (8.33e-3)" "unprognostic (9.56e-3)" "unprognostic (2.71e-1)" "unprognostic (1.40e-1)" "unprognostic (5.40e-3)" 24.9 27.1 16.0 27.6 20.3 18.3 24.2 19.1 17.6 21.4 31.3 24.6 22.4 36.6 20.6 22.8 31.6 17.6 25.0 33.9 15.1 14.5 51.2 46.5 17.9 18.2 23.1 9.9 24.3 23.2 27.2 16.2 18.6 19.7 22.4 31.8 20.4 31.4 21.5 73.8 20.6 37.1 18.7 25.9 24.7 24.0 29.3 25.0 40.2 37.4 34.4 28.7 26.7 23.3 31.7 51.9 50.9 41.2 27.4 24.4 43.1 44.8 20.0 18.9 21.9 13.1 16.4 19.2 25.4 19.6 38.2 40.2 38.3 40.8 83.7 30.1 18.8 32.6 43.8 43.1 41.2 36.5 32.0 55.4 38.4 29.1 30.6 98.6 31.4 16.2 32.6 32.7 66.1 26.1 58.8 31.5 22.6 22.6 37.3 54.5 26.4 30.7 43.5 32.1 55.1 37.6 27.1 27.8 16.3 29.0 32.2 80.9 26.2 70.1 19.0 23.2 28.0 35.6 47.4 32.9 43.0 78.0 31.5 93.3 26.7 11.0 41.2 50.9 22.0 37.4 23.0 31.7 20.6 20.6 51.9 27.7 21.2 19.8 11.3 27.4 31.5 39.1 24.4 43.1 16.0 20.3 19.1 17.6 15.1 14.5 23.1 9.9 19.7 25.0 AK3 "AK3L1, AK6, AKL3L1" ENSG00000147853 "Adenylate kinase 3" Q9UIJ7 9 4709559-4742043 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 85.0;HEL: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063324 Enhanced Supported Mitochondria 68000 Mitochondria "HPA063324: " "unprognostic (1.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (6.55e-2)" "unprognostic (1.02e-1)" "unprognostic (2.21e-3)" "unprognostic (6.44e-2)" "unprognostic (2.81e-2)" "unprognostic (9.81e-3)" "unprognostic (1.90e-1)" "unprognostic (2.76e-2)" "prognostic favourable (6.07e-9)" "unprognostic (1.24e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.55e-3)" 24.6 25.1 20.9 9.8 22.4 6.8 24.0 14.6 17.5 17.7 23.7 15.3 16.0 24.4 18.9 17.5 28.3 14.0 16.1 90.0 22.4 16.4 37.7 75.1 16.4 13.1 25.2 15.2 22.4 15.7 16.9 14.1 13.0 22.9 19.0 23.0 17.4 14.5 19.1 72.0 18.1 22.0 21.2 24.1 12.1 22.5 9.3 24.9 15.2 20.8 32.8 14.9 20.1 17.1 7.0 14.4 17.0 5.6 14.7 17.1 10.2 8.7 7.3 12.5 5.1 17.5 12.9 0.9 11.0 26.0 6.9 10.4 1.2 9.7 8.1 3.8 14.0 5.6 9.1 10.6 11.8 85.0 6.9 54.4 13.0 22.0 13.8 5.7 2.8 20.4 9.5 5.9 8.2 20.3 4.1 11.1 20.7 5.2 5.5 16.5 11.2 2.7 7.4 4.5 4.0 20.2 12.2 20.7 13.0 12.9 4.2 7.4 5.8 11.4 12.6 5.8 5.9 15.2 8.6 2.8 1.8 10.0 10.6 4.3 4.1 6.8 5.6 17.0 16.2 4.4 14.7 7.0 12.5 14.8 10.5 6.9 16.6 17.1 1.9 14.7 3.4 14.4 16.7 10.2 20.9 22.4 14.6 17.5 22.4 16.4 25.2 15.2 22.9 24.9 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 89.7;liver: 50.7" "Cell line enhanced" "Detected in many" "Hep G2: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 6.1;myeloid DC: 5.3" "Group enriched" "Detected in many" 7 "dendritic cells: 5.3;granulocytes: 1.6;monocytes: 6.1" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" 18000 Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavourable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavourable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavourable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavourable (4.36e-4)" "prognostic unfavourable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 12.4 1.6 11.7 3.7 11.2 2.7 13.4 12.0 9.9 4.0 9.5 4.0 4.7 2.7 3.9 4.4 12.3 4.2 8.6 26.0 9.3 7.1 89.7 50.7 1.6 1.4 6.3 9.1 5.8 1.8 8.2 2.6 4.5 7.2 8.9 7.7 4.4 9.4 7.3 2.2 14.0 3.5 13.6 8.1 1.2 7.8 6.0 5.0 0.4 1.9 5.7 3.2 12.4 7.4 0.5 5.3 1.6 6.1 0.6 0.5 1.4 20.2 1.4 1.6 6.9 15.3 14.6 3.5 3.4 4.3 7.4 20.8 30.4 2.4 10.9 9.0 5.3 13.1 5.4 25.6 30.0 9.1 6.2 10.6 6.8 58.2 0.7 8.2 1.3 8.1 14.4 7.3 21.4 0.2 13.1 0.1 11.3 8.7 0.3 0.3 7.1 12.2 0.0 11.9 1.9 11.0 0.9 5.9 4.5 6.1 0.4 4.8 8.5 3.6 1.2 12.4 10.7 0.9 5.8 11.5 5.1 0.6 20.1 3.0 0.7 1.6 6.1 0.0 0.2 1.4 0.4 0.5 0.2 0.5 5.3 0.4 0.2 0.2 1.0 0.6 0.2 0.8 0.1 1.4 11.7 11.2 12.0 9.9 9.3 7.1 6.3 9.1 7.2 5.0 AK5 ENSG00000154027 "Adenylate kinase 5" Q9Y6K8 1 77282051-77559969 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 95.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 29.7;BJ: 20.3;fHDF/TERT166: 23.1;LHCN-M2: 58.2;U-2 OS: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 10.9;naive CD4 T-cell: 14.2" "Group enriched" "Detected in many" 15 "dendritic cells: 10.9;T-cells: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019128, HPA057255" Enhanced Supported "Centriolar satellite,Cytosol" Cytosol "Centriolar satellite" "HPA019128: AB_1844682, HPA057255: " "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (1.13e-1)" "unprognostic (2.85e-2)" "unprognostic (1.03e-1)" "unprognostic (6.04e-2)" "unprognostic (2.20e-1)" "unprognostic (2.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.91e-2)" "prognostic favourable (3.88e-4)" "unprognostic (3.56e-3)" "unprognostic (6.17e-4)" "unprognostic (1.18e-1)" "unprognostic (5.96e-2)" "unprognostic (6.76e-2)" 1.8 2.1 43.8 1.9 35.7 3.7 14.1 1.3 95.5 2.0 1.8 20.4 0.0 1.8 1.6 1.5 1.8 1.8 1.7 1.5 35.8 11.8 2.0 1.2 1.4 2.5 13.0 41.1 1.5 2.1 2.4 1.4 1.8 11.4 2.7 1.8 0.0 3.1 2.7 1.3 2.4 1.7 1.7 14.2 2.4 2.9 7.3 13.9 0.0 1.7 0.0 2.1 1.5 0.4 0.8 10.9 0.7 0.7 0.1 14.2 1.9 0.0 1.1 0.8 0.0 10.9 29.7 0.4 20.3 4.3 3.3 1.4 0.1 0.5 0.1 0.1 23.1 0.1 0.0 0.0 1.7 0.7 0.2 0.1 0.1 0.0 0.5 0.1 0.0 3.6 0.1 0.6 1.3 9.5 0.2 0.2 58.2 0.2 0.0 0.1 1.1 7.4 0.5 2.1 0.3 9.0 0.3 4.5 1.1 0.0 0.0 1.2 0.1 0.1 2.3 8.0 18.2 0.4 0.6 4.7 4.2 0.0 1.6 1.0 2.9 0.7 0.7 0.0 3.4 0.1 0.5 0.8 3.2 1.6 10.9 0.8 14.2 7.8 0.5 0.1 0.2 1.2 1.4 1.9 43.8 35.7 1.3 47.1 35.8 11.8 13.0 41.1 11.4 13.9 AK6 CINAP ENSG00000085231 "Adenylate kinase 6" Q9Y3D8 5 69350984-69370013 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005361, HPA070217" Supported Supported "Nuclear speckles,Centrosome,Cytosol" "Nuclear speckles" "Centrosome, Cytosol" "CAB005361: AB_2302969, HPA070217: " "unprognostic (5.47e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (8.58e-2)" "unprognostic (8.73e-2)" "unprognostic (4.09e-2)" "prognostic unfavourable (9.54e-4)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" "unprognostic (6.21e-2)" "unprognostic (2.55e-2)" "unprognostic (2.25e-2)" "unprognostic (1.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" 27.6 27.7 25.1 16.9 25.4 14.8 23.3 21.5 23.6 17.6 22.7 11.3 16.4 18.3 18.3 30.4 26.7 15.4 15.1 17.9 23.2 22.2 30.2 42.3 17.0 18.7 20.9 16.2 18.8 17.2 15.8 26.3 21.5 23.3 18.2 20.6 12.3 14.5 14.6 41.4 11.9 24.0 16.7 19.6 21.8 17.0 46.1 17.5 25.2 24.3 24.2 18.8 19.7 13.7 22.2 22.0 14.3 15.9 16.6 21.2 10.0 17.2 9.6 12.6 16.8 20.7 13.8 23.7 26.0 9.8 12.8 15.9 26.8 14.9 37.0 24.6 11.8 5.8 19.7 12.4 19.6 15.1 9.5 18.2 20.5 20.4 16.9 21.6 7.9 8.0 16.4 12.7 18.3 8.3 17.0 12.2 16.4 20.0 19.9 14.6 10.5 6.4 23.4 15.7 20.5 20.1 14.1 6.5 6.4 13.4 10.8 18.6 11.5 24.4 10.9 9.6 15.4 17.9 21.5 14.7 30.6 32.8 12.4 31.8 12.4 13.7 13.0 14.3 15.5 15.9 16.1 22.2 18.4 19.3 18.0 18.1 20.1 21.2 2.1 16.6 14.2 22.0 18.1 10.0 25.1 25.4 21.5 23.6 23.2 22.2 20.9 16.2 23.3 17.5 AK7 FLJ32864 ENSG00000140057 "Adenylate kinase 7" Q96M32 14 96392111-96489427 "Enzymes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 29.0" "Cell line enhanced" "Detected in some" "BEWO: 10.4;CAPAN-2: 9.0;MCF7: 28.7;REH: 20.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 17 "basophil: 10.6" "Lineage enriched" "Detected in single" 22 "granulocytes: 10.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003543 Enhanced "HPA003543: AB_1078117" "unprognostic (4.18e-3)" "unprognostic (1.14e-1)" "unprognostic (9.40e-3)" "prognostic favourable (3.18e-4)" "unprognostic (4.98e-5)" "unprognostic (8.41e-2)" "unprognostic (9.81e-3)" "unprognostic (1.29e-1)" "unprognostic (9.02e-2)" "unprognostic (3.65e-4)" "unprognostic (8.64e-2)" "unprognostic (1.89e-1)" "prognostic favourable (1.14e-4)" "unprognostic (2.00e-2)" "unprognostic (1.23e-2)" "unprognostic (4.01e-2)" "unprognostic (2.25e-3)" 1.5 3.4 4.0 0.9 12.6 2.0 2.1 0.7 3.1 2.7 2.8 8.4 5.1 2.5 2.8 13.1 2.4 29.0 5.0 1.2 6.7 9.2 7.6 3.0 9.2 1.4 2.3 2.6 4.9 2.9 11.7 17.5 0.9 16.7 1.4 2.2 1.5 1.6 2.9 0.5 7.5 3.1 1.6 2.7 4.3 3.5 17.6 4.2 1.1 4.8 1.3 0.8 1.1 1.5 0.4 0.1 10.6 0.3 0.3 0.4 0.2 0.1 2.9 1.2 1.0 0.5 1.7 10.4 0.1 0.3 0.2 0.1 0.3 9.0 0.2 0.2 0.1 1.1 2.8 0.1 0.1 1.3 0.2 0.2 1.3 0.1 0.5 0.1 0.1 0.1 0.4 1.5 0.0 0.1 0.1 0.2 0.2 28.7 0.2 0.2 0.5 0.6 20.4 0.3 0.3 4.5 0.2 2.0 4.1 1.1 0.4 0.0 2.5 0.1 0.0 0.3 0.1 0.3 0.1 0.4 1.3 0.1 0.1 0.0 0.4 10.6 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.4 0.1 0.4 0.2 0.2 0.6 0.3 0.3 0.1 0.1 0.2 4.0 12.6 0.7 3.1 6.7 9.2 2.3 2.6 16.7 4.2 AK8 "C9orf98, FLJ32704" ENSG00000165695 "Adenylate kinase 8" Q96MA6 9 132725578-132878777 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 12.8;fallopian tube: 17.7;testis: 15.6" "Cell line enhanced" "Detected in some" "AN3-CA: 3.1;MCF7: 5.2;RPTEC TERT1: 6.0;T-47d: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 8 "NK-cell: 3.9" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021443, HPA023894" Enhanced "HPA021443: AB_1845852, HPA023894: AB_1845854" "unprognostic (4.14e-2)" "unprognostic (1.20e-4)" "unprognostic (1.31e-2)" "unprognostic (1.70e-3)" "unprognostic (2.16e-1)" "unprognostic (2.38e-2)" "unprognostic (1.14e-1)" "unprognostic (3.18e-1)" "unprognostic (3.43e-1)" "unprognostic (1.71e-1)" "unprognostic (7.51e-2)" "unprognostic (1.42e-1)" "prognostic favourable (1.61e-4)" "unprognostic (9.89e-2)" "unprognostic (3.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.43e-1)" 0.5 0.7 1.3 0.5 2.2 0.0 0.5 1.6 1.3 1.6 0.5 0.5 0.5 0.0 1.1 12.8 0.5 17.7 0.7 0.5 1.3 2.0 1.4 0.5 1.1 0.5 1.2 0.5 0.9 0.5 2.5 1.7 1.5 2.3 0.5 0.0 0.9 1.0 1.8 0.5 1.1 0.5 0.5 1.7 0.5 0.3 15.6 0.5 0.5 3.1 0.5 0.5 0.5 0.5 0.1 0.0 0.0 0.0 3.9 0.5 0.0 2.0 1.0 0.6 3.1 0.4 0.8 0.6 0.3 0.2 0.2 0.0 0.4 2.1 0.0 0.7 0.3 0.5 0.2 0.0 0.1 0.1 0.7 0.0 0.2 0.0 1.3 0.0 0.0 1.8 0.9 0.3 0.6 0.2 0.1 0.0 0.5 5.2 1.5 0.4 0.2 0.6 0.0 0.0 0.0 6.0 0.0 1.1 1.2 2.6 0.0 0.4 4.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.3 2.2 1.6 1.0 1.3 2.0 1.2 0.5 2.3 0.5 AK9 "AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1, FLJ25791, FLJ42177, MGC26954" ENSG00000155085 "Adenylate kinase 9" Q5TCS8 6 109492856-109691217 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA030804, HPA030805, HPA031779, HPA031781, HPA036324, HPA036711" Enhanced Enhanced "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA030804: , HPA030805: , HPA031779: AB_10603674, HPA031781: , HPA036324: , HPA036711: " "unprognostic (9.68e-3)" "unprognostic (2.15e-1)" "unprognostic (1.66e-2)" "unprognostic (2.36e-2)" "unprognostic (3.42e-1)" "unprognostic (7.28e-2)" "unprognostic (1.41e-3)" "unprognostic (6.76e-3)" "unprognostic (1.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-4)" "unprognostic (2.58e-1)" "unprognostic (2.98e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (8.39e-2)" "unprognostic (5.56e-2)" 4.6 4.7 7.7 5.6 8.4 4.7 8.3 13.5 8.7 5.0 6.5 8.5 4.1 5.0 6.3 11.1 6.2 11.3 5.2 6.9 9.1 10.3 7.6 4.5 6.7 5.5 9.4 4.9 6.7 4.6 15.4 33.3 4.4 11.5 5.9 6.7 3.7 7.0 6.3 6.1 5.5 6.2 5.7 11.7 6.5 6.1 22.0 7.7 20.5 11.4 4.1 5.0 5.9 4.4 11.2 2.9 15.1 4.1 4.9 6.4 1.6 2.6 1.8 7.7 13.7 7.2 4.5 5.7 4.0 5.0 4.2 5.8 2.9 5.3 5.6 2.1 3.8 4.6 2.2 4.4 9.0 11.9 4.8 4.2 4.5 2.9 5.9 5.3 2.6 3.6 8.5 7.8 10.2 5.5 4.0 4.7 3.1 5.3 4.6 3.6 1.7 2.9 6.1 4.3 5.2 6.2 5.1 9.4 8.0 4.9 4.7 6.7 6.0 6.5 5.9 4.1 2.7 5.9 2.6 2.5 2.1 3.3 8.2 6.7 2.2 15.1 2.8 6.5 5.1 1.5 4.4 10.5 5.1 6.1 2.0 11.2 6.4 5.5 5.4 4.9 4.1 2.9 3.6 1.6 7.7 8.4 13.5 8.7 9.1 10.3 9.4 4.9 11.5 7.7 AKR1A1 "ALR, DD3" ENSG00000117448 "Aldo-keto reductase family 1 member A1" P14550 1 45550543-45570049 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006246, HPA017919, HPA019649, HPA027734" Approved Supported Nucleoplasm,Cytosol 8100000 Cytosol Nucleoplasm "CAB006246: AB_425840, HPA017919: AB_1844695, HPA019649: AB_1844696, HPA027734: AB_10600976" "unprognostic (1.73e-1)" "prognostic favourable (2.66e-6)" "unprognostic (4.03e-1)" "prognostic favourable (2.92e-4)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (1.31e-3)" "unprognostic (2.52e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (8.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.56e-2)" "unprognostic (2.46e-1)" "unprognostic (2.89e-2)" "unprognostic (4.57e-2)" 20.0 20.4 12.0 27.9 13.9 9.7 31.8 11.5 23.6 21.7 39.6 18.7 20.0 43.6 18.5 31.7 39.0 21.8 31.7 18.5 11.2 12.0 79.6 80.4 26.0 33.8 15.0 13.9 18.3 44.2 11.3 27.5 20.2 13.1 19.4 28.9 16.7 59.8 24.1 13.4 18.2 69.7 19.4 16.3 25.6 27.7 10.5 13.1 24.8 24.6 31.3 33.2 17.4 18.6 23.3 46.8 26.8 56.3 13.8 18.7 38.4 16.4 23.8 21.8 16.8 47.4 34.5 15.4 19.6 45.7 17.1 34.5 9.9 12.7 40.7 15.7 22.3 21.1 22.9 28.5 16.1 16.4 20.6 23.5 20.2 43.4 39.6 30.3 26.4 38.0 25.8 21.6 40.2 39.5 12.0 32.6 20.0 11.9 32.4 13.2 23.7 16.4 37.4 26.2 47.1 48.6 22.5 26.0 15.0 16.9 67.6 24.7 18.9 17.4 24.0 7.9 17.6 27.4 11.6 22.5 29.9 19.1 15.5 39.6 6.8 26.8 56.3 10.5 16.3 51.8 17.8 23.3 15.3 16.0 46.8 22.7 13.1 13.5 2.6 13.8 38.1 40.8 18.7 38.4 12.0 13.9 11.5 23.6 11.2 12.0 15.0 13.9 13.1 13.1 AKR1B1 "ALDR1, AR" ENSG00000085662 "Aldo-keto reductase family 1 member B" P15121 7 134442350-134459284 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 302.2;seminal vesicle: 109.3" "Cell line enhanced" "Detected in many" "A549: 121.0;BJ hTERT+: 222.0;RPTEC TERT1: 105.0;U-87 MG: 99.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026425, CAB027391, CAB047353, HPA052751" Enhanced Supported Nucleoplasm,Cytosol 1700000 Cytosol Nucleoplasm "CAB027391: , CAB047353: , HPA026425: AB_10601563, HPA052751: " "unprognostic (2.76e-2)" "unprognostic (2.84e-2)" "unprognostic (2.02e-2)" "unprognostic (1.37e-2)" "unprognostic (6.81e-2)" "unprognostic (2.26e-1)" "unprognostic (4.18e-2)" "unprognostic (5.09e-2)" "unprognostic (2.51e-3)" "unprognostic (2.47e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "prognostic unfavourable (2.44e-5)" "unprognostic (2.03e-1)" "unprognostic (1.39e-1)" "prognostic unfavourable (7.00e-4)" 5.9 302.2 7.5 4.7 13.7 2.5 9.5 6.9 10.9 4.4 3.9 8.2 50.4 2.7 4.6 6.1 4.2 4.6 5.2 24.2 7.3 8.4 17.7 2.5 6.9 10.0 9.5 9.0 8.2 7.2 9.4 8.0 24.8 11.9 5.5 4.1 5.8 4.4 109.3 37.6 2.8 4.8 5.6 7.9 6.7 5.0 5.2 5.9 7.3 6.0 10.3 7.6 7.1 3.7 31.4 34.8 22.5 26.0 26.3 42.7 47.2 13.3 121.0 13.6 19.3 58.9 16.0 36.3 13.0 222.0 19.1 24.8 5.6 12.3 0.0 6.0 21.7 5.7 14.8 12.9 15.2 4.8 13.6 6.8 18.2 16.4 84.4 0.0 0.0 14.9 9.7 27.3 7.3 26.9 0.0 4.5 21.1 0.2 20.0 9.2 22.7 0.1 20.9 8.7 10.1 105.0 65.4 10.2 22.7 90.9 0.1 9.5 0.0 10.2 21.2 18.9 8.8 1.7 14.1 12.5 13.7 33.8 99.9 0.0 11.3 22.5 26.0 1.2 37.9 17.0 34.0 31.4 32.4 36.7 34.8 28.5 42.7 41.1 2.1 26.3 8.9 4.9 22.0 47.2 7.5 13.7 6.9 10.9 7.3 8.4 9.5 9.0 11.9 5.9 AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549136-134579875 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 61.7;placenta: 31.8" "Cell line enhanced" "Detected in some" "A549: 15.1;HDLM-2: 12.0;Hep G2: 10.5;SK-BR-3: 5.1;U-87 MG: 6.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "basophil: 1.8" "Lineage enhanced" "Detected in single" "granulocytes: 1.8" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA020280: AB_10602228, HPA073633: " "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (9.74e-3)" "unprognostic (2.74e-2)" "unprognostic (2.08e-1)" "prognostic favourable (8.36e-4)" "prognostic unfavourable (1.80e-5)" "unprognostic (5.04e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-1)" "unprognostic (2.14e-3)" "unprognostic (1.24e-1)" "unprognostic (1.22e-7)" "unprognostic (6.88e-2)" "unprognostic (4.29e-1)" "unprognostic (2.99e-3)" "prognostic unfavourable (1.90e-5)" 2.7 0.1 0.1 0.1 0.1 0.0 61.7 0.1 0.2 1.6 0.6 0.2 0.1 5.6 0.1 1.5 3.8 0.0 2.2 0.1 0.1 0.0 0.1 0.8 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 31.8 0.2 0.8 0.2 0.5 2.9 0.1 11.6 1.9 1.7 0.8 0.4 0.1 5.0 0.6 0.1 0.3 0.4 16.1 1.8 1.5 3.0 0.1 0.0 1.8 0.1 0.4 0.0 0.3 0.0 15.1 0.1 0.0 0.6 0.5 0.9 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 12.0 0.0 0.1 0.1 10.5 0.0 0.2 0.5 0.0 0.2 0.1 0.1 0.0 0.1 0.5 0.0 0.0 0.2 0.2 3.1 0.0 0.1 0.2 0.3 0.0 0.1 0.1 0.1 0.5 5.1 0.0 0.0 0.3 0.0 0.1 0.7 0.3 0.0 0.2 0.2 0.2 6.5 0.2 0.2 1.8 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.1 AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 145.9;tongue: 74.5" "Group enriched" "Detected in many" 10 "ASC diff: 186.6;Hep G2: 316.4" "Cancer enhanced" "Detected in many" "liver cancer: 64.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 4.2" "Low lineage specificity" "Detected in many" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: " "unprognostic (1.54e-2)" "prognostic favourable (3.05e-4)" "unprognostic (4.04e-2)" "unprognostic (8.38e-2)" "unprognostic (3.18e-2)" "unprognostic (7.05e-2)" "prognostic unfavourable (1.56e-4)" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (8.38e-2)" "unprognostic (4.65e-1)" "unprognostic (1.82e-2)" "prognostic favourable (8.03e-9)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (6.30e-2)" 52.0 3.8 2.1 3.4 4.1 1.4 36.0 2.6 2.7 2.2 3.2 2.6 1.2 6.2 1.4 4.0 19.2 1.7 16.1 22.1 2.6 2.6 32.0 145.9 11.2 2.5 5.4 1.4 3.8 4.9 0.6 4.1 0.7 6.6 5.1 3.2 3.8 13.1 3.4 17.1 4.7 4.6 4.8 6.8 0.9 21.9 5.2 3.2 0.0 11.5 74.5 5.0 17.4 10.8 0.0 0.9 4.2 0.1 0.3 1.7 0.8 0.0 25.6 0.1 25.8 186.6 22.5 0.0 0.8 5.7 0.3 0.2 0.5 0.0 0.0 0.3 5.8 0.2 0.0 1.3 0.1 0.0 0.0 0.7 4.2 316.4 1.8 0.1 0.0 11.4 1.6 2.7 1.6 0.6 5.5 0.0 4.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 4.8 0.0 0.1 1.4 0.0 0.0 0.0 0.4 5.0 2.2 0.1 5.9 0.2 0.1 0.0 0.0 7.9 0.7 0.0 4.2 0.1 1.1 1.7 0.0 0.1 0.0 0.7 0.4 0.2 0.0 0.3 1.5 0.9 0.3 0.0 0.9 0.4 0.8 2.1 4.1 2.6 2.7 2.6 2.6 5.4 1.4 6.6 3.2 AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987400-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 71.9;liver: 122.7;tongue: 111.8" "Group enriched" "Detected in some" 4 "A549: 134.6;ASC diff: 167.1;Hep G2: 251.2;RT4: 76.9" "Group enriched" "Detected in many" 6 "cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 5 "plasmacytoid DC: 1.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.4" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: " "unprognostic (6.77e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-2)" "unprognostic (8.65e-2)" "unprognostic (5.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.25e-3)" "unprognostic (8.58e-2)" "unprognostic (1.09e-2)" "unprognostic (8.60e-3)" "unprognostic (1.46e-2)" "unprognostic (8.30e-2)" 60.4 4.0 1.8 2.0 3.3 0.0 71.9 2.5 2.1 1.3 2.9 1.0 1.2 5.5 1.0 3.0 17.4 1.5 19.4 9.3 1.7 2.3 4.8 122.7 5.9 1.1 4.7 0.9 1.9 2.4 0.0 1.8 0.1 4.2 8.1 2.4 2.0 12.0 2.4 19.8 4.2 2.4 4.4 3.9 0.6 26.2 2.3 2.6 0.1 4.2 111.8 5.5 25.3 11.9 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 134.6 0.1 14.2 167.1 5.7 0.0 0.0 0.5 0.0 0.1 0.5 0.0 0.0 0.7 0.9 3.8 0.0 0.7 0.0 0.0 0.0 0.0 38.0 251.2 0.3 0.0 0.0 14.9 8.4 0.7 0.7 0.0 5.1 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.2 76.9 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.5 0.3 0.1 4.9 0.0 0.0 0.0 0.0 1.7 2.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 1.8 3.3 2.5 2.1 1.7 2.3 4.7 0.9 4.2 2.6 AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 50.1;intestine: 52.3" "Cell line enhanced" "Detected in many" "A549: 149.2;AN3-CA: 43.6;ASC diff: 85.8;HeLa: 46.2;Hep G2: 62.6;RT4: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 50.1;gdT-cell: 26.7" "Low lineage specificity" "Detected in many" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" 11000000 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: " "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavourable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" 16.6 6.6 3.2 3.2 3.9 3.5 12.8 3.2 3.9 3.2 17.3 3.2 3.2 52.3 3.2 3.2 6.0 4.5 32.2 4.8 4.4 1.0 20.1 34.4 5.5 3.2 3.2 3.2 3.2 4.2 1.8 3.2 3.2 4.2 3.2 11.4 3.2 4.4 3.2 13.0 2.6 31.1 4.2 3.2 3.2 28.6 3.2 3.2 3.2 3.2 3.2 3.2 12.3 3.2 0.1 9.6 50.1 0.7 4.6 26.7 9.7 0.0 149.2 0.1 43.6 85.8 30.9 0.0 0.0 2.1 0.0 0.1 4.4 2.5 0.0 8.1 2.0 1.2 0.1 2.9 0.0 0.3 0.0 0.2 46.2 62.6 0.4 0.0 0.0 17.1 6.1 2.0 0.0 2.8 0.9 0.0 3.9 0.3 1.0 0.2 0.0 0.4 0.3 0.9 4.4 14.7 58.9 0.0 0.3 21.4 0.0 0.0 0.0 0.0 20.8 0.5 0.4 9.0 0.3 0.0 0.0 0.0 5.0 5.9 0.4 50.1 0.7 1.1 26.7 0.2 1.7 0.0 5.0 4.8 0.5 0.1 3.2 2.4 1.9 4.6 0.3 9.6 4.9 9.7 3.2 3.9 3.2 3.9 4.4 1.0 3.2 3.2 4.2 3.2 AKR1C4 "3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581" ENSG00000198610 "Aldo-keto reductase family 1 member C4" P17516 10 5195462-5218949 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 127.0" "Cell line enriched" "Detected in some" 6 "HDLM-2: 11.8" "Cancer enriched" "Detected in some" 86 "liver cancer: 108.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 1.2;gdT-cell: 1.1" "Group enriched" "Detected in many" 6 "granulocytes: 1.2;T-cells: 1.1" "HPA044720, HPA068265" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" 1800000 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA044720: , HPA068265: " "unprognostic (2.21e-1)" "unprognostic (3.04e-1)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (5.99e-2)" "unprognostic (9.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (1.29e-1)" "unprognostic (3.31e-1)" "unprognostic (7.34e-2)" "unprognostic (1.45e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 127.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 1.1 0.1 0.0 1.5 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.5 0.3 1.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.2 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 AKR1D1 SRD5B1 ENSG00000122787 "Aldo-keto reductase family 1 member D1" P51857 7 138002324-138117986 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease mutation, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 103.2" "Cell line enriched" "Detected in single" 20 "Hep G2: 16.5" "Cancer enriched" "Detected in single" 77 "liver cancer: 20.1" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA057002 Enhanced Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA057002: " "unprognostic (2.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.02e-2)" "unprognostic (1.52e-2)" "prognostic favourable (9.91e-5)" "unprognostic (6.11e-2)" "unprognostic (2.31e-1)" "unprognostic (1.30e-1)" "unprognostic (6.87e-2)" "unprognostic (2.94e-1)" "unprognostic (9.68e-3)" "unprognostic (2.90e-1)" "unprognostic (5.80e-2)" "unprognostic (3.11e-1)" "unprognostic (1.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 2.7 0.5 0.7 0.7 0.2 0.2 0.0 0.2 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.8 0.2 0.2 0.1 0.0 0.3 0.0 0.0 0.2 0.3 0.1 0.4 0.3 16.5 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.3 0.2 0.1 0.2 0.1 0.4 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.1 0.2 0.4 0.2 0.2 0.1 0.3 0.2 0.3 0.3 0.2 0.2 0.2 0.3 2.7 0.5 0.6 0.4 0.4 0.3 0.6 0.4 0.4 0.3 1.1 0.5 0.7 1.8 0.7 0.5 0.5 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 AKR1E2 "AKR1CL2, AKRDC1, MGC10612" ENSG00000165568 "Aldo-keto reductase family 1 member E2" Q96JD6 10 4786629-4848062 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "testis: 35.0" "Cell line enhanced" "Detected in many" "CACO-2: 8.2;RT4: 9.6;U-2197: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 3.2;myeloid DC: 1.6;naive CD4 T-cell: 1.4;plasmacytoid DC: 1.8" "Group enriched" "Detected in many" 5 "dendritic cells: 1.8;granulocytes: 3.2;T-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037821, HPA037822" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA037821: , HPA037822: AB_10671722" "unprognostic (2.33e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (8.27e-2)" "unprognostic (7.33e-2)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (7.42e-3)" "unprognostic (7.47e-2)" "unprognostic (2.77e-2)" "unprognostic (1.32e-1)" "unprognostic (1.53e-1)" "unprognostic (3.06e-2)" "unprognostic (2.74e-1)" "unprognostic (2.04e-2)" "unprognostic (1.62e-4)" "unprognostic (5.62e-2)" 3.3 1.6 1.8 3.2 2.6 2.4 4.2 1.4 2.5 2.6 2.3 0.7 3.4 1.8 5.0 1.7 1.9 1.4 5.0 2.7 1.5 1.5 1.8 1.1 4.4 2.8 1.4 2.1 1.5 2.7 3.7 1.2 2.6 1.9 1.7 1.7 5.0 1.9 2.6 2.3 2.0 1.7 2.9 2.1 1.5 2.1 35.0 0.9 0.8 4.5 2.0 0.6 1.7 2.9 0.1 1.8 3.2 0.4 0.0 1.4 0.3 0.4 5.3 2.0 0.9 0.0 0.0 0.1 2.1 0.1 0.1 0.0 8.2 0.8 0.0 0.0 5.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 1.0 5.6 1.0 0.0 6.0 4.6 0.0 0.0 4.9 0.6 0.0 2.2 3.9 0.0 0.0 0.0 1.5 9.6 0.0 4.5 7.7 2.1 4.1 4.1 2.2 3.6 0.0 1.8 18.3 0.0 2.5 0.0 0.0 0.1 0.0 1.5 3.2 0.4 0.3 0.1 0.2 0.0 0.1 0.4 0.2 1.6 0.0 1.4 0.4 0.1 0.0 0.0 1.8 0.0 0.3 1.8 2.6 1.4 2.5 1.5 1.5 1.4 2.1 1.9 0.9 AKR7A2 AFAR ENSG00000053371 "Aldo-keto reductase family 7 member A2" O43488 1 19303965-19312146 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032587, CAB032841, HPA064638" Enhanced Supported Cytosol 2700000 Cytosol "CAB032587: AB_673379, CAB032841: AB_2224545, HPA064638: " "unprognostic (1.06e-1)" "unprognostic (3.48e-2)" "unprognostic (7.23e-2)" "unprognostic (5.76e-2)" "unprognostic (9.92e-2)" "unprognostic (1.09e-1)" "unprognostic (1.14e-2)" "unprognostic (3.14e-3)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (5.11e-2)" "unprognostic (7.11e-2)" "prognostic favourable (2.67e-4)" "unprognostic (3.72e-2)" "unprognostic (8.53e-2)" "unprognostic (1.01e-1)" "prognostic unfavourable (8.59e-4)" 21.2 39.0 25.2 14.0 26.9 15.2 22.0 19.8 26.2 32.9 38.5 28.1 28.7 56.0 20.2 23.0 25.7 35.1 31.9 31.2 22.0 19.4 49.3 32.4 14.4 21.9 24.9 26.2 31.6 60.8 14.8 19.0 17.2 23.6 19.9 19.5 25.8 21.4 24.9 33.8 18.8 43.1 20.8 20.0 16.3 22.3 21.6 21.4 24.7 22.9 20.2 18.3 16.7 21.6 23.0 40.1 13.7 29.0 22.2 27.1 23.5 24.2 15.3 16.8 15.5 26.7 26.0 11.2 18.1 22.2 25.5 22.9 19.4 20.5 17.6 19.4 24.3 19.4 18.8 27.3 12.1 14.0 29.8 11.0 14.8 31.0 20.8 12.1 8.9 25.8 21.6 19.5 12.0 21.5 16.0 16.5 26.0 24.2 23.6 11.8 4.8 19.3 24.9 21.0 31.0 24.8 10.7 31.7 11.8 19.8 17.9 30.5 35.6 42.4 16.8 16.0 16.9 17.1 13.5 20.1 12.6 21.4 34.5 27.9 22.5 0.1 29.0 13.7 23.0 23.7 26.8 23.0 20.7 20.3 40.1 21.4 23.9 20.6 3.4 22.2 17.8 35.0 27.1 23.5 25.2 26.9 19.8 26.2 22.0 19.4 24.9 26.2 23.6 21.4 AKT1 "AKT, PKB, PRKBA, RAC" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 30.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 30.7" "Low region specificity" "Detected in all" "HPA002891, CAB003765" Supported Supported Nucleoplasm,Microtubules Nucleoplasm Microtubules "CAB003765: AB_562035, HPA002891: AB_1078123" "unprognostic (3.30e-2)" "unprognostic (4.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (9.17e-3)" "unprognostic (1.55e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "prognostic favourable (4.83e-4)" "unprognostic (3.58e-2)" "unprognostic (1.90e-2)" "prognostic favourable (2.12e-4)" "unprognostic (7.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 31.7 45.4 22.9 24.2 23.6 20.3 40.0 20.9 29.5 24.7 32.6 20.0 30.8 22.5 27.0 21.5 33.0 25.5 30.3 47.7 22.9 19.1 26.3 49.2 31.3 21.0 22.1 14.7 25.9 43.0 20.3 16.7 28.4 21.5 31.1 18.2 25.3 30.4 36.1 23.8 20.4 24.0 40.5 17.5 35.4 32.6 16.2 18.8 26.3 32.7 22.4 29.3 36.7 35.9 3.2 5.2 30.7 5.8 5.7 6.2 3.0 15.1 30.3 25.0 37.2 19.4 20.1 28.0 27.9 34.0 41.3 33.1 19.8 18.3 18.3 21.5 38.2 19.7 17.7 26.0 18.0 41.8 7.2 13.9 18.1 21.3 21.5 22.6 36.3 28.8 21.9 20.7 13.8 30.8 12.1 20.4 26.4 113.2 28.4 28.9 6.5 21.7 26.8 23.2 12.5 19.1 37.7 28.7 23.9 23.3 30.5 17.5 39.9 33.7 24.6 27.7 13.3 39.4 28.0 22.2 10.7 15.8 23.3 19.1 33.3 3.3 5.3 30.7 5.4 5.2 4.0 2.9 4.8 6.2 3.6 3.2 2.5 5.7 11.8 5.7 5.8 5.2 4.7 3.0 22.9 23.6 20.9 29.5 22.9 19.1 22.1 14.7 21.5 18.8 AKT2 ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: " "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavourable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavourable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 31.1 20.3 15.4 17.6 15.2 21.3 18.2 46.3 18.2 23.3 18.2 23.4 21.2 12.3 22.8 28.0 22.1 22.7 14.0 23.1 15.4 10.0 23.0 62.5 14.6 17.8 17.9 13.3 27.8 24.5 21.1 24.0 17.5 14.7 19.7 12.3 26.8 18.5 24.3 48.5 18.3 17.1 20.0 16.8 18.7 15.5 21.3 15.7 26.6 52.6 29.5 23.6 19.6 19.9 6.3 8.8 7.7 4.4 3.2 4.9 2.4 22.4 55.4 21.1 21.7 26.3 32.2 11.7 15.0 22.2 31.1 27.8 24.3 20.9 22.9 13.4 33.1 9.8 23.4 31.3 20.1 21.9 26.7 15.0 35.1 15.3 16.5 17.2 18.1 29.7 18.8 21.1 20.1 6.7 19.3 24.0 17.3 18.7 27.3 8.4 11.4 14.9 18.2 11.5 16.5 24.2 36.8 29.1 17.8 15.4 26.4 12.5 20.8 22.2 6.7 19.0 18.8 17.0 23.5 22.4 19.2 18.8 18.6 20.4 15.5 7.6 4.4 3.6 4.5 2.0 4.5 3.9 3.6 3.0 3.0 6.3 3.5 4.9 7.7 3.2 2.6 8.8 2.7 2.4 15.4 15.2 46.3 18.2 15.4 10.0 17.9 13.3 14.7 15.7 AKT3 "PKBG, PRKBG, RAC-gamma" ENSG00000117020 "AKT serine/threonine kinase 3" Q9Y243 1 243488233-243851079 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013090, HPA026441" Approved Supported Cytosol Cytosol "CAB013090: AB_2533692, HPA026441: AB_1844711" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.96e-1)" "unprognostic (3.77e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-1)" "unprognostic (5.47e-3)" "unprognostic (1.37e-1)" "unprognostic (6.71e-2)" "unprognostic (3.64e-3)" "unprognostic (1.29e-1)" "unprognostic (8.14e-2)" "prognostic unfavourable (9.27e-4)" 15.4 17.0 16.0 7.8 15.2 2.2 11.0 39.9 33.4 16.9 16.1 12.4 17.4 4.1 19.7 12.3 10.0 11.8 12.1 9.8 15.5 13.6 12.8 4.0 11.3 7.9 14.2 15.8 29.8 4.4 15.1 14.6 17.0 18.4 19.4 6.6 8.9 4.1 23.9 4.8 4.7 8.1 20.4 12.1 9.9 8.7 10.4 14.8 2.9 17.7 5.0 6.2 17.2 18.6 1.9 0.8 1.2 0.9 3.8 3.6 0.6 23.5 2.4 14.9 0.0 11.0 12.6 7.9 13.3 12.2 8.6 7.6 0.1 9.7 0.0 0.0 16.8 0.3 8.2 5.3 11.4 5.9 6.4 0.3 0.0 0.0 5.7 0.1 2.6 6.5 0.0 10.7 9.7 17.6 0.0 0.1 3.9 0.0 5.0 1.1 6.3 3.7 2.7 9.1 0.1 2.9 0.8 19.1 25.3 0.1 0.0 23.8 0.0 8.0 13.8 15.3 11.8 0.1 11.0 1.3 0.4 2.8 11.2 1.2 12.8 1.2 0.9 0.5 2.3 0.3 3.6 1.0 2.2 2.5 0.8 1.9 1.9 1.7 0.2 3.8 0.7 0.6 0.7 0.6 16.0 15.2 39.9 22.9 15.5 13.6 14.2 15.8 18.4 14.8 ALAD "ALADH, PBGS" ENSG00000148218 "Aminolevulinate dehydratase" P13716 9 113386317-113401333 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" "Allosteric enzyme, Lyase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 84.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021023, HPA022124" Enhanced 44000000 "HPA021023: AB_1844716, HPA022124: AB_1844717" "unprognostic (2.75e-1)" "unprognostic (6.26e-2)" "prognostic unfavourable (7.33e-5)" "prognostic favourable (5.64e-4)" "unprognostic (4.16e-2)" "unprognostic (9.49e-2)" "prognostic favourable (8.80e-5)" "unprognostic (2.87e-3)" "unprognostic (3.49e-1)" "unprognostic (2.95e-1)" "unprognostic (1.62e-1)" "unprognostic (3.31e-2)" "prognostic favourable (1.65e-4)" "unprognostic (1.75e-1)" "unprognostic (1.22e-1)" "unprognostic (3.40e-1)" "unprognostic (1.31e-2)" 19.9 70.3 24.1 6.4 26.3 27.3 13.7 14.0 24.8 8.3 10.5 28.3 8.8 11.6 7.5 11.5 14.6 6.8 13.0 23.3 24.6 20.8 29.9 84.2 8.4 5.9 37.5 20.6 12.3 18.8 24.1 7.2 10.2 27.9 14.5 10.2 9.8 37.2 15.1 10.6 15.6 10.7 8.9 40.1 5.9 18.1 5.4 28.6 4.7 10.9 6.6 7.5 9.0 8.0 7.6 12.1 19.1 13.1 5.5 9.7 7.6 3.4 6.0 4.7 6.6 32.9 22.7 30.0 9.3 15.7 6.2 7.8 8.3 7.2 4.8 5.7 13.2 12.7 3.4 6.4 3.6 12.0 4.3 9.6 7.5 10.9 7.5 8.7 8.2 19.1 4.8 5.6 2.5 12.1 3.6 7.2 10.1 25.1 10.0 8.7 2.4 11.9 7.9 8.2 8.3 9.6 7.2 4.3 4.1 11.8 14.4 8.5 15.2 10.0 13.1 5.5 4.2 10.8 5.2 10.7 10.0 3.8 15.5 8.1 5.9 7.2 11.5 19.1 9.7 13.1 5.4 5.9 8.4 5.4 12.1 7.6 8.1 8.9 5.6 5.5 12.7 4.9 8.5 7.6 24.1 26.3 14.0 24.8 24.6 20.8 37.5 20.6 27.9 28.6 ALAS1 "ALAS, ALAS3" ENSG00000023330 "5'-aminolevulinate synthase 1" P13196 3 52198086-52214327 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 167.6;liver: 136.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "basophil: 55.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 55.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017498, HPA035860" Enhanced Enhanced Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB017498: AB_2225629, HPA035860: AB_10672992" "unprognostic (1.17e-1)" "unprognostic (1.65e-1)" "unprognostic (1.50e-1)" "unprognostic (7.09e-2)" "unprognostic (2.33e-1)" "unprognostic (6.21e-2)" "prognostic favourable (1.82e-5)" "unprognostic (3.98e-2)" "unprognostic (1.26e-1)" "unprognostic (2.31e-2)" "unprognostic (9.86e-2)" "unprognostic (5.64e-2)" "prognostic favourable (6.06e-7)" "unprognostic (8.45e-2)" "unprognostic (3.91e-2)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" 9.2 167.6 7.8 6.7 10.6 39.1 8.9 17.0 15.4 6.0 11.0 12.0 15.3 11.4 6.3 11.8 10.5 4.7 8.7 24.8 8.8 7.0 14.1 136.4 13.5 10.0 7.6 9.9 5.8 6.1 8.5 5.8 13.4 12.2 7.3 11.1 8.3 15.7 16.9 24.6 6.8 17.4 6.5 7.3 6.3 12.2 9.7 5.0 7.5 7.4 11.4 9.6 12.1 7.6 6.8 8.4 55.0 12.2 8.8 11.3 6.3 10.4 16.2 11.5 10.6 18.0 13.4 31.4 15.4 14.3 20.6 20.0 21.6 19.8 9.8 3.9 10.7 6.2 16.5 12.6 16.9 19.0 6.4 12.6 12.8 16.4 25.5 20.4 25.3 16.7 11.9 32.7 10.9 18.8 7.4 8.1 18.7 8.5 9.6 31.0 9.9 28.2 5.8 7.2 15.5 18.1 63.4 6.1 4.0 24.9 12.3 13.9 7.0 29.0 13.5 11.5 11.4 23.7 22.2 12.0 20.8 14.8 12.9 22.1 18.3 55.0 9.2 27.8 6.9 12.2 11.3 6.8 7.2 7.7 8.4 6.0 6.5 7.0 14.2 8.8 10.2 4.8 9.7 6.3 7.8 10.6 17.0 15.4 8.8 7.0 7.6 9.9 12.2 5.0 ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605929-95656706 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 68.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Supported Mitochondria 23000 Mitochondria "HPA008333: AB_1078125, HPA012604: AB_1844721" "unprognostic (5.97e-3)" "unprognostic (2.08e-2)" "unprognostic (5.75e-2)" "prognostic favourable (4.20e-4)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-3)" "unprognostic (7.08e-2)" "unprognostic (4.06e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "prognostic unfavourable (3.60e-9)" "unprognostic (1.02e-3)" "unprognostic (6.57e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" 6.3 10.4 7.1 10.4 7.9 5.2 7.7 7.3 9.3 13.7 20.1 7.2 20.5 33.8 9.3 12.3 12.8 8.5 15.2 7.2 6.2 7.1 13.0 28.9 6.6 7.4 6.7 5.3 14.5 40.7 12.7 17.4 14.3 7.7 9.6 19.4 7.9 68.8 20.5 3.5 9.6 45.4 10.0 5.4 8.6 15.2 8.4 5.4 12.7 25.9 9.7 15.9 8.6 8.2 13.1 5.2 0.3 4.0 13.0 16.3 8.0 18.2 17.3 16.6 43.6 22.4 21.7 17.9 21.3 32.1 21.7 27.3 34.6 14.6 62.1 20.0 33.5 24.2 33.3 21.9 24.7 17.6 26.2 19.7 12.3 49.1 14.7 34.3 22.0 22.7 13.5 17.7 34.7 22.7 18.3 13.1 16.2 26.2 31.0 22.1 19.6 17.3 29.2 19.1 21.3 25.3 13.9 16.6 16.5 16.9 13.5 15.7 20.1 16.0 18.8 9.0 14.4 23.2 24.4 15.1 11.2 38.0 17.6 39.8 11.5 0.0 1.4 0.1 15.5 2.7 16.3 13.1 14.2 16.0 5.2 9.0 12.1 13.4 0.3 13.0 4.0 3.1 13.3 8.0 7.1 7.9 7.3 9.3 6.2 7.1 6.7 5.3 7.7 5.4 ALDH1A1 "ALDH1, PUMB1, RALDH1" ENSG00000165092 "Aldehyde dehydrogenase 1 family member A1" P00352 9 72900662-73080442 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 207.2" "Cell line enhanced" "Detected in some" "A549: 287.9;Hep G2: 88.6;RPTEC TERT1: 51.3" "Cancer enhanced" "Detected in all" "liver cancer: 399.1" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "classical monocyte: 34.2" "Lineage enriched" "Detected in many" 30 "monocytes: 34.2" "Region enriched" "Detected in many" 6 "midbrain: 171.1" "HPA002123, CAB020690" Approved Approved Enhanced Cytosol 62000000 Cytosol "CAB020690: , HPA002123: AB_1844722" "unprognostic (8.46e-3)" "prognostic favourable (7.77e-5)" "unprognostic (5.59e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-2)" "unprognostic (8.71e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (4.53e-2)" "unprognostic (6.83e-2)" "unprognostic (4.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.24e-3)" "unprognostic (2.20e-1)" "unprognostic (2.36e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-3)" 20.0 26.9 8.8 12.3 21.4 3.9 10.8 44.8 11.7 33.6 53.6 14.5 65.3 77.1 25.5 87.1 14.5 27.8 38.3 8.9 12.5 5.9 86.7 207.2 31.4 9.4 56.4 3.6 35.8 69.7 0.7 57.5 7.9 14.0 20.0 13.1 30.2 31.8 40.3 12.1 2.7 76.5 17.1 29.1 16.3 75.5 43.0 14.9 2.0 45.8 21.0 16.8 14.1 16.0 0.3 0.5 1.1 34.2 0.0 0.1 10.5 0.0 287.9 0.0 0.0 1.6 0.0 0.1 10.0 0.0 0.0 0.0 9.6 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.3 0.0 88.6 1.0 0.0 0.0 0.5 0.0 0.0 0.0 10.3 1.1 0.0 11.0 0.4 0.0 0.1 0.0 0.0 0.0 3.2 0.1 51.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.2 0.5 0.0 5.8 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.0 1.1 0.0 0.4 0.3 0.0 10.5 8.8 21.4 44.8 11.7 12.5 5.9 56.4 3.6 14.0 14.9 ALDH1A2 RALDH2 ENSG00000128918 "Aldehyde dehydrogenase 1 family member A2" O94788 15 57953424-58497866 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "AN3-CA: 70.8;HEK 293: 23.6;K-562: 60.6;MOLT-4: 73.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 22 "neutrophil: 22.6" "Lineage enriched" "Detected in single" 56 "granulocytes: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010022 Approved "HPA010022: AB_1844723" "unprognostic (1.11e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" "unprognostic (1.44e-2)" "unprognostic (1.16e-2)" "unprognostic (1.04e-4)" "unprognostic (1.08e-1)" "unprognostic (9.03e-3)" "unprognostic (6.92e-3)" "unprognostic (5.48e-2)" "unprognostic (6.19e-2)" "unprognostic (2.57e-3)" "unprognostic (3.18e-2)" "unprognostic (4.95e-2)" "unprognostic (1.99e-2)" "unprognostic (1.80e-3)" 11.4 2.3 0.6 1.9 1.0 1.3 6.5 0.9 0.9 23.1 1.9 0.7 32.7 0.1 43.1 14.7 2.3 29.1 16.8 17.3 1.8 0.4 8.4 1.3 7.0 0.9 0.7 1.1 12.7 1.2 19.1 18.1 12.8 2.5 13.3 0.0 24.4 2.4 29.5 3.1 1.0 0.9 11.3 2.1 1.6 0.6 39.9 0.4 2.3 1.0 2.6 0.4 2.8 12.3 0.0 0.0 22.6 0.4 0.0 0.0 0.0 0.2 0.0 0.0 70.8 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.1 2.2 0.0 0.1 0.0 23.6 0.0 0.6 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 4.2 60.6 0.0 0.0 0.0 73.2 0.0 0.1 3.4 0.0 0.1 0.0 12.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 0.2 0.0 0.0 0.0 0.6 1.0 0.9 0.9 1.8 0.4 0.7 1.1 2.5 0.4 ALDH1A3 "ALDH6, RALDH3" ENSG00000184254 "Aldehyde dehydrogenase 1 family member A3" P47895 15 100877714-100916626 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 42.0;HaCaT: 52.3;HBEC3-KT: 129.5;U-2197: 74.4;U-87 MG: 59.2;WM-115: 61.1" "Group enriched" "Detected in many" 7 "melanoma: 16.8;prostate cancer: 80.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 1.0;eosinophil: 2.1;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.5;granulocytes: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046271, HPA064749" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA046271: AB_10965992, HPA064749: " "unprognostic (6.87e-2)" "unprognostic (2.23e-1)" "unprognostic (6.20e-3)" "unprognostic (1.21e-3)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (6.28e-2)" "unprognostic (5.46e-2)" "unprognostic (9.62e-2)" "unprognostic (4.53e-2)" "unprognostic (3.64e-2)" "unprognostic (2.56e-1)" "unprognostic (1.25e-2)" "unprognostic (2.61e-2)" "unprognostic (2.12e-1)" "unprognostic (7.34e-2)" "unprognostic (6.07e-3)" 30.3 5.7 2.3 14.9 1.6 0.0 11.1 4.1 2.6 14.2 11.5 1.6 10.5 5.2 5.9 37.9 10.5 11.5 15.0 6.1 2.1 2.0 3.7 1.7 4.2 5.5 2.6 1.7 9.0 7.4 3.2 13.2 5.1 3.9 51.9 3.2 49.9 41.5 19.2 6.1 1.7 15.6 14.2 6.4 1.5 5.3 15.9 0.7 0.6 0.9 15.2 18.9 18.0 9.8 0.3 1.5 2.1 0.2 0.0 0.0 0.1 42.0 5.6 0.0 0.0 9.3 4.1 0.1 0.3 0.3 0.2 0.1 0.1 33.7 0.3 0.5 11.3 52.3 1.0 129.5 0.8 0.0 0.2 0.2 2.3 0.0 3.1 0.1 0.2 2.9 3.6 2.9 0.5 0.4 0.0 0.2 0.2 0.4 0.0 0.2 1.1 34.2 0.0 0.5 0.2 0.0 35.3 0.0 3.0 13.1 11.5 3.9 1.1 0.3 6.6 0.0 0.1 74.4 1.6 0.0 0.3 0.2 59.2 0.0 61.1 1.0 0.2 2.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 2.3 1.6 4.1 2.6 2.1 2.0 2.6 1.7 3.9 0.7 ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392664-38398661 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 113.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021037 Approved Supported Nucleoplasm,Vesicles,Mitochondria 210000 Mitochondria "Nucleoplasm, Vesicles" "HPA021037: AB_1844724" "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favourable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavourable (1.17e-5)" "unprognostic (2.89e-2)" 7.4 4.9 2.1 16.8 2.1 0.6 5.4 1.1 5.4 5.8 25.4 1.7 6.1 7.0 27.3 10.7 21.6 16.7 30.8 11.6 3.1 2.0 18.0 55.2 3.5 5.9 2.4 2.0 12.2 14.6 1.4 1.4 1.6 3.0 22.7 11.5 5.2 5.9 18.2 19.4 3.0 11.2 113.9 2.7 2.8 15.8 7.8 1.7 1.6 6.3 7.0 2.0 54.5 8.3 5.9 9.4 1.2 10.5 7.5 10.2 5.1 23.9 22.3 6.9 11.0 9.8 11.7 5.5 11.5 5.8 9.7 10.0 14.9 4.7 15.1 6.9 16.1 3.4 22.7 24.3 9.7 16.9 9.8 7.5 16.4 44.2 7.1 11.9 8.5 13.9 5.3 7.9 6.9 9.2 21.6 14.8 14.7 9.1 0.0 4.8 20.5 10.0 4.9 41.8 11.5 8.7 10.8 15.1 7.0 8.7 5.8 6.7 5.5 9.3 6.2 11.2 18.6 9.3 14.3 2.2 4.3 6.0 5.8 12.2 7.6 0.2 4.2 0.2 7.3 9.1 10.2 5.9 7.0 6.6 9.4 3.1 5.8 6.8 1.2 7.5 10.5 1.3 4.8 5.1 2.1 2.1 1.1 5.4 3.1 2.0 2.4 2.0 3.0 1.7 ALDH1L1 "10-fTHF, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 48.1;liver: 148.7" "Cell line enhanced" "Detected in some" "Hep G2: 23.4;Karpas-707: 24.1;RPMI-8226: 12.6;RT4: 64.5;U-266/70: 13.3" "Cancer enhanced" "Detected in many" "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol 640000 Cytosol "HPA036900: AB_10672273, HPA050139: AB_2681031" "unprognostic (5.93e-2)" "unprognostic (1.22e-1)" "unprognostic (9.12e-2)" "unprognostic (2.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (4.73e-2)" "unprognostic (3.05e-3)" "unprognostic (8.40e-2)" "prognostic favourable (2.42e-8)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (7.03e-3)" "unprognostic (7.93e-2)" 28.9 12.1 13.7 1.8 17.1 1.2 6.0 8.6 10.9 7.8 4.9 5.7 2.3 1.1 1.9 2.2 3.6 3.4 1.9 8.1 8.9 5.3 48.1 148.7 1.3 1.2 9.2 10.1 11.3 10.2 1.4 0.9 1.1 10.8 3.3 3.3 5.1 34.1 4.1 30.7 1.5 1.3 2.4 7.7 1.1 1.9 4.9 6.2 0.0 1.7 6.2 2.8 11.0 3.1 0.1 0.8 0.8 0.2 0.2 0.4 0.0 0.4 0.0 0.0 0.0 10.6 0.0 0.1 0.1 0.4 0.1 0.2 0.0 0.9 0.7 3.1 0.0 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.1 23.4 3.1 3.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 24.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.6 0.3 64.5 0.1 0.1 0.3 3.1 0.0 0.0 0.0 0.1 0.4 1.9 0.0 0.0 13.3 4.1 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.4 0.2 0.2 0.2 0.0 0.8 0.1 0.0 13.7 17.1 8.6 10.9 8.9 5.3 9.2 10.1 10.8 6.2 ALDH1L2 "FLJ38508, mtFDH" ENSG00000136010 "Aldehyde dehydrogenase 1 family member L2" Q3SY69 12 105019784-105084577 "Enzymes, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "pancreas: 48.9;salivary gland: 31.6" "Cell line enhanced" "Detected in many" "ASC diff: 22.6;ASC TERT1: 30.9;fHDF/TERT166: 35.1;HHSteC: 19.9;HSkMC: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 6 "dendritic cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039481, HPA059282" Approved Enhanced Mitochondria Mitochondria "HPA039481: AB_10795465, HPA059282: " "unprognostic (5.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.76e-1)" "unprognostic (8.86e-2)" "unprognostic (1.75e-1)" "unprognostic (2.92e-1)" "unprognostic (5.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-8)" "unprognostic (3.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.53e-3)" "unprognostic (2.52e-5)" 4.2 1.2 3.2 2.7 1.9 0.7 2.7 5.3 2.7 5.5 2.2 0.9 3.3 2.4 2.9 3.2 1.5 2.6 2.7 2.9 1.6 2.0 0.7 0.4 2.7 2.0 2.0 2.1 1.0 48.9 0.7 2.8 1.1 2.5 3.6 2.3 4.8 31.6 4.5 1.0 1.5 1.3 5.4 5.3 1.2 3.7 0.8 1.3 0.0 2.2 1.4 3.0 3.9 2.2 0.2 1.3 0.0 0.1 0.0 0.1 0.1 4.3 0.4 0.2 9.4 22.6 30.9 0.5 14.0 9.0 1.8 4.8 0.5 0.0 0.0 0.5 35.1 0.0 0.0 0.3 2.3 0.0 0.1 0.2 0.0 1.1 19.9 1.7 0.0 25.0 1.1 4.7 8.9 1.0 0.7 12.6 3.6 0.0 0.0 0.1 0.5 0.1 0.0 0.0 1.3 0.0 0.0 3.3 1.6 0.0 2.9 7.1 2.0 14.9 0.1 1.4 1.3 0.0 0.7 15.7 4.1 0.0 5.7 6.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.1 3.2 1.9 5.3 2.4 1.6 2.0 2.0 2.1 2.5 1.3 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family (mitochondrial)" P05091 12 111766887-111817529 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 279.7" "Cell line enhanced" "Detected in many" "ASC diff: 26.2;HHSteC: 29.4;SK-BR-3: 59.1;THP-1: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 45.8;myeloid DC: 46.6" "Group enriched" "Detected in many" 4 "dendritic cells: 46.6;monocytes: 45.8" HPA051065 Approved 1400000 "HPA051065: " "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favourable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favourable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favourable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavourable (7.71e-4)" 88.9 34.0 42.1 17.0 44.6 9.9 39.6 14.3 30.9 10.4 25.3 17.5 16.8 25.6 9.0 11.6 26.4 10.3 28.5 45.0 30.9 24.2 59.0 279.7 38.1 13.3 34.1 32.6 16.1 14.0 2.2 7.6 4.0 30.6 13.5 26.2 13.1 17.9 30.7 40.1 43.5 25.5 29.4 26.6 8.0 34.9 9.5 23.8 3.3 12.0 28.1 18.2 17.0 22.9 1.4 46.6 10.8 45.8 0.7 0.2 21.7 2.4 3.8 5.5 9.4 26.2 3.9 18.0 2.6 4.9 1.2 0.9 6.7 3.5 0.1 13.5 5.9 4.7 0.0 1.3 0.8 0.1 1.8 0.2 2.4 18.2 29.4 0.2 0.2 7.2 6.7 4.4 0.1 7.8 4.9 0.8 1.2 0.1 0.2 6.6 7.3 0.6 0.1 0.1 0.5 9.1 0.1 2.2 6.8 6.6 59.1 0.0 5.9 26.3 0.3 0.1 5.0 0.1 0.1 1.6 0.8 7.1 6.5 0.2 0.1 0.9 45.8 10.8 0.1 20.1 0.2 1.4 0.0 0.1 46.6 1.2 0.1 0.1 2.3 0.7 5.0 15.5 0.1 21.7 42.1 44.6 14.3 30.9 30.9 24.2 34.1 32.6 30.6 23.8 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.2;lymphoid tissue: 70.3;stomach 1: 49.9;tongue: 106.6" "Cell line enriched" "Detected in some" 20 "A549: 321.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 1.8" "Cell type enhanced" "Detected in some" "NK-cell: 2.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: , HPA063783: " "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favourable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 0.7 0.1 0.2 0.8 0.4 0.0 0.5 0.2 0.3 1.3 0.9 0.8 0.3 1.3 0.2 0.4 88.2 1.2 3.8 0.2 0.4 0.0 0.4 0.4 26.0 0.2 0.2 0.3 0.6 0.2 0.0 0.3 0.2 1.8 0.5 0.6 0.5 26.7 0.3 0.4 16.2 0.6 0.3 0.3 0.3 49.9 0.3 0.2 0.2 0.2 106.6 70.3 1.6 3.9 1.1 0.3 0.0 0.0 2.4 0.7 0.1 0.0 321.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 16.1 0.0 0.1 0.0 1.9 0.0 0.8 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 5.7 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.3 1.1 0.0 0.7 0.0 2.4 0.0 0.0 0.0 0.1 0.2 0.4 0.2 0.3 0.4 0.0 0.2 0.3 1.8 0.2 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19677598 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Approved "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favourable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 22.3 66.4 8.5 9.0 24.6 2.8 10.0 8.8 12.8 13.7 15.9 17.5 7.5 15.6 13.5 19.2 39.6 10.7 26.4 12.5 9.5 6.5 52.5 88.6 17.7 4.3 11.1 10.3 13.5 24.4 10.1 14.9 3.1 14.4 20.7 11.1 16.2 26.0 10.0 18.5 57.1 26.6 10.5 10.2 8.0 18.3 9.8 15.4 4.5 27.3 27.9 22.5 9.8 17.0 3.9 14.3 11.6 14.2 8.6 6.4 5.7 6.7 42.3 4.2 10.6 20.2 17.1 2.9 2.0 5.2 4.0 4.6 13.2 11.0 2.1 4.9 8.4 15.1 16.6 20.3 2.9 9.4 7.2 1.0 22.3 32.3 3.8 5.0 0.5 9.4 28.9 3.8 2.3 8.0 0.2 0.1 10.1 9.1 0.1 6.2 10.1 23.2 4.9 12.1 6.4 4.7 21.4 8.2 5.8 18.5 7.1 5.9 12.4 4.6 9.5 2.6 4.7 6.8 6.3 2.9 7.2 3.0 12.6 0.0 8.4 0.0 14.2 11.6 4.2 12.6 6.4 3.9 4.3 3.7 14.3 3.0 4.9 3.4 0.7 8.6 13.7 0.2 5.8 5.7 8.5 24.6 8.8 12.8 9.5 6.5 11.1 10.3 14.4 15.4 ALDH3B1 ALDH7 ENSG00000006534 "Aldehyde dehydrogenase 3 family member B1" P43353 11 68008578-68029282 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 39.8" "Cell line enhanced" "Detected in many" "A549: 44.5;CAPAN-2: 45.9;U-87 MG: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 39.8" "Group enriched" "Detected in many" 10 "dendritic cells: 17.6;granulocytes: 39.8;monocytes: 32.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038525 Uncertain "HPA038525: " "unprognostic (3.50e-1)" "unprognostic (4.22e-1)" "prognostic unfavourable (1.18e-4)" "unprognostic (1.56e-2)" "unprognostic (9.66e-3)" "unprognostic (9.73e-2)" "unprognostic (7.93e-3)" "unprognostic (2.62e-1)" "unprognostic (2.01e-1)" "unprognostic (1.06e-1)" "prognostic unfavourable (6.07e-4)" "unprognostic (8.27e-2)" "unprognostic (6.49e-3)" "unprognostic (1.00e-1)" "unprognostic (2.75e-2)" "unprognostic (6.69e-3)" "unprognostic (1.06e-1)" 9.1 9.8 1.8 5.0 2.5 21.4 2.4 1.3 2.3 6.2 7.8 4.2 1.1 11.8 4.0 7.0 4.0 21.0 13.7 3.1 2.6 2.4 9.3 5.1 28.5 14.3 4.3 1.4 6.6 12.9 0.0 3.8 13.4 3.8 4.6 3.1 7.8 5.7 2.0 2.0 1.8 21.4 4.2 5.6 11.7 10.4 2.9 1.9 0.7 1.7 1.5 3.3 7.6 3.8 0.1 17.6 39.8 32.9 2.9 0.1 9.8 3.2 44.5 0.3 0.9 3.0 9.6 8.1 4.5 7.5 3.3 1.6 1.6 45.9 0.2 8.1 10.5 3.8 0.1 0.6 0.8 0.1 0.3 0.4 17.9 3.9 18.9 2.6 0.1 6.9 2.0 1.6 4.4 0.1 0.1 8.1 5.2 2.7 0.2 2.5 0.3 2.7 1.0 1.7 24.5 5.3 0.4 0.5 0.2 10.5 8.8 4.4 10.2 5.8 5.0 4.7 6.7 22.9 1.5 0.1 0.8 0.0 27.1 7.3 2.1 11.8 23.0 39.8 0.0 32.9 0.1 0.1 0.0 0.0 17.6 0.1 0.0 0.0 6.9 2.9 29.1 1.8 0.0 9.8 1.8 2.5 1.3 2.3 2.6 2.4 4.3 1.4 3.8 1.9 ALDH3B2 ALDH8 ENSG00000132746 "Aldehyde dehydrogenase 3 family member B2" P48448 11 67662162-67681200 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "breast: 28.1;esophagus: 48.2;lymphoid tissue: 34.2;skin 1: 38.7" "Group enriched" "Detected in some" 5 "MCF7: 30.9;SK-BR-3: 32.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" HPA045132 Approved "HPA045132: AB_10795993" "unprognostic (2.25e-1)" "unprognostic (2.41e-1)" "unprognostic (1.65e-1)" "unprognostic (8.65e-2)" "unprognostic (2.13e-1)" "unprognostic (6.09e-2)" "unprognostic (3.12e-2)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-2)" "unprognostic (5.92e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 28.1 0.1 0.1 6.7 0.1 0.1 5.0 0.0 1.5 2.4 48.2 1.5 0.1 0.1 0.1 0.0 0.6 0.1 0.6 0.1 0.1 0.1 0.4 0.1 0.6 0.3 11.2 0.1 1.8 0.0 0.1 17.1 4.6 0.1 38.7 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.8 0.1 25.7 34.2 4.6 11.6 1.0 0.1 0.6 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 1.8 1.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 30.9 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.0 0.0 32.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902781 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 73.7;liver: 92.6" "Cell line enhanced" "Detected in many" "Hep G2: 33.9;SK-BR-3: 35.0" "Cancer enhanced" "Detected in all" "liver cancer: 72.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401" Enhanced 40000 "CAB004645: AB_425775, HPA006401: AB_1844731" "unprognostic (1.17e-1)" "prognostic favourable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-3)" "unprognostic (9.41e-3)" "unprognostic (3.83e-1)" "unprognostic (2.69e-3)" "unprognostic (9.34e-2)" 22.9 4.1 14.4 2.0 18.0 4.6 6.6 3.1 16.8 3.8 2.4 8.6 18.9 1.3 2.5 5.2 11.4 2.7 3.0 12.6 8.6 7.1 73.7 92.6 2.4 1.7 15.9 11.2 2.9 2.2 9.4 2.4 8.3 8.5 12.1 1.6 9.7 2.4 12.1 25.6 8.0 1.3 3.3 2.7 2.1 3.4 1.4 6.6 2.8 3.0 8.9 2.9 8.3 3.6 1.5 7.2 2.6 5.6 0.3 1.4 2.2 5.0 7.9 4.0 11.9 17.0 2.5 9.8 4.8 3.0 5.0 4.0 5.7 3.8 3.4 6.5 6.2 13.5 6.8 14.4 1.8 1.9 6.0 1.9 1.8 33.9 5.3 1.6 6.1 6.6 8.1 2.8 2.7 5.6 7.5 2.5 3.4 12.9 1.6 8.2 1.9 4.0 10.5 3.3 3.9 5.2 12.8 7.9 3.0 8.5 35.0 6.3 15.9 2.6 4.6 4.3 5.7 5.2 1.7 2.7 6.5 0.9 1.5 13.2 5.7 0.0 4.1 2.6 1.1 5.6 0.9 1.5 0.7 1.4 7.2 1.1 0.3 0.9 0.6 0.3 3.1 2.4 1.0 2.2 14.4 18.0 3.1 16.8 8.6 7.1 15.9 11.2 8.5 6.6 ALDH5A1 "SSADH, SSDH" ENSG00000112294 "Aldehyde dehydrogenase 5 family member A1" P51649 6 24494852-24537207 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 62.6" "Cell line enhanced" "Detected in many" "Daudi: 40.3;U-698: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029715, HPA029716" Enhanced Supported Mitochondria 44000 Mitochondria "HPA029715: AB_10599994, HPA029716: AB_10601876" "unprognostic (7.43e-2)" "unprognostic (1.12e-3)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "prognostic favourable (7.61e-6)" "unprognostic (2.38e-2)" "unprognostic (2.17e-2)" "prognostic favourable (6.20e-4)" "unprognostic (1.43e-2)" "unprognostic (1.21e-1)" "prognostic favourable (3.68e-4)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.00e-2)" "unprognostic (1.08e-2)" 5.8 4.8 23.7 8.3 27.4 3.1 4.1 13.5 21.5 4.1 6.0 9.5 1.2 7.7 3.9 3.1 5.6 13.5 4.4 9.8 17.3 21.0 18.4 62.6 5.0 8.9 16.0 14.7 5.8 6.6 11.4 4.5 2.2 13.0 6.2 5.7 4.1 3.9 4.3 31.1 6.9 5.4 2.8 10.9 4.8 5.2 3.7 8.8 21.4 12.1 4.9 8.8 6.3 5.5 3.9 3.8 0.4 0.2 1.6 6.8 1.2 3.2 2.9 2.1 3.1 0.0 0.0 3.5 0.3 0.6 0.8 0.5 11.5 0.8 40.3 6.1 0.3 0.0 3.4 0.4 0.5 4.1 5.6 6.3 1.9 13.1 0.5 9.7 0.8 0.3 1.6 0.1 0.0 0.0 3.1 0.0 0.6 7.5 11.8 5.8 0.8 1.5 13.6 0.6 0.3 2.4 6.4 3.6 3.2 3.8 0.4 3.9 5.7 5.3 0.0 0.4 2.0 0.1 2.0 5.7 8.5 50.3 0.0 3.1 0.4 0.4 0.1 0.2 1.7 0.0 3.3 3.7 2.4 2.8 0.2 3.9 6.8 5.7 0.4 1.6 0.2 3.8 1.6 1.2 23.7 27.4 13.5 21.5 17.3 21.0 16.0 14.7 13.0 8.8 ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056850-74084493 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 140.0;liver: 134.5" "Cell line enhanced" "Detected in all" "T-47d: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 25.5" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria 9100 Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favourable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favourable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" 14.1 6.9 31.3 2.8 30.9 2.3 6.7 11.6 26.4 8.0 11.0 20.1 4.6 11.0 5.5 5.5 5.0 6.2 4.8 15.6 21.1 14.2 140.0 134.5 4.7 3.0 19.4 18.5 12.3 11.8 16.4 3.2 4.0 14.8 11.0 7.2 7.1 7.8 7.8 10.5 3.4 9.3 5.6 13.1 3.1 9.6 7.4 18.7 2.0 12.1 4.0 3.1 6.3 3.3 4.5 5.6 25.5 3.8 5.5 6.7 2.8 4.6 4.0 5.7 12.1 20.8 10.2 9.2 3.2 6.1 3.5 6.0 9.0 5.2 5.4 7.2 6.9 2.7 12.9 3.6 7.7 4.8 1.8 2.5 4.2 9.9 23.7 1.3 1.2 15.0 6.5 4.5 11.4 6.1 4.0 7.5 2.4 17.7 3.7 2.0 4.5 2.7 7.6 5.9 7.1 5.6 3.5 2.3 3.6 10.7 11.6 2.8 29.6 4.8 1.9 4.0 4.9 6.2 1.2 5.1 9.1 5.5 5.2 1.6 3.8 13.3 3.8 25.5 4.5 2.9 6.7 4.5 5.1 5.3 5.6 3.6 6.5 4.6 1.5 5.5 2.4 3.2 3.6 2.8 31.3 30.9 11.6 26.4 21.1 14.2 19.4 18.5 14.8 18.7 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595418 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 64.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 9.7" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023296 Enhanced Supported Mitochondria,Cytosol 140000 Mitochondria Cytosol "HPA023296: AB_1844738" "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favourable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 9.0 14.2 46.0 3.4 39.1 0.8 18.8 11.0 22.5 14.0 11.5 23.1 7.2 9.5 10.5 7.5 13.5 11.9 7.8 10.8 35.0 17.3 46.5 64.4 6.4 3.1 28.7 18.5 27.6 10.8 17.7 5.9 17.7 16.9 17.6 11.2 13.7 15.0 12.2 4.5 11.9 8.1 9.8 20.2 2.8 9.0 4.9 28.4 4.0 19.4 10.1 7.4 7.2 7.1 1.3 9.7 0.7 0.3 0.1 1.8 0.6 14.8 9.8 27.8 46.0 23.2 13.8 35.5 17.8 22.0 20.7 26.8 27.6 14.3 0.0 18.2 13.9 11.1 8.6 60.2 19.1 0.0 10.4 2.8 14.7 23.4 11.3 0.0 0.0 16.9 14.2 16.1 11.6 16.5 0.0 0.0 18.2 9.7 0.6 0.0 18.8 8.3 8.9 31.6 0.0 19.7 11.3 9.5 11.3 0.0 9.8 10.3 17.7 0.6 20.0 6.0 18.6 6.9 12.2 0.0 0.0 0.0 3.2 0.0 9.6 0.7 0.3 0.1 0.2 0.0 0.3 1.3 0.3 0.2 2.7 1.1 1.8 1.0 0.3 0.1 0.0 9.7 0.1 0.6 46.0 39.1 11.0 22.5 35.0 17.3 28.7 18.5 16.9 28.4 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" 1100000 Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favourable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 39.1 52.7 30.8 17.4 25.4 7.7 39.6 16.2 26.6 20.3 18.0 22.7 17.1 19.5 15.5 35.5 47.0 18.8 22.2 22.2 24.8 21.1 50.5 73.5 20.7 20.4 23.7 18.4 20.6 17.8 31.2 19.2 14.1 22.8 24.6 18.7 27.2 52.2 23.2 29.9 22.6 23.9 19.2 21.9 18.8 14.7 37.3 21.5 12.4 45.1 24.2 27.9 18.5 19.1 29.6 20.2 29.4 24.5 23.1 39.0 24.4 17.4 17.1 16.0 14.3 51.2 45.1 13.4 23.2 32.9 23.3 20.3 10.6 13.2 0.0 22.2 20.7 13.8 12.9 22.6 27.7 8.1 16.4 11.1 12.3 11.5 26.4 17.5 11.9 28.9 11.5 24.7 20.8 20.2 17.6 15.8 36.3 10.5 11.6 18.0 23.3 21.1 10.0 20.4 23.4 30.3 16.6 19.0 13.1 16.5 18.6 21.2 35.5 26.6 19.9 14.1 13.8 17.2 11.7 14.7 19.2 17.5 15.9 16.7 13.5 26.8 20.3 28.1 28.3 21.5 30.1 29.6 27.7 30.6 20.2 26.0 28.1 32.0 29.4 23.1 24.5 12.6 39.0 24.4 30.8 25.4 16.2 26.6 24.8 21.1 23.7 18.4 22.8 21.5 ALDOA ENSG00000149925 "Aldolase, fructose-bisphosphate A" P04075 16 30064164-30070457 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease mutation, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "skeletal muscle: 1296.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA004177, CAB006252" Enhanced Supported Cytosol 1200000000 Cytosol "CAB006252: AB_437007, HPA004177: AB_1078128" "unprognostic (2.63e-2)" "unprognostic (3.22e-2)" "unprognostic (6.80e-2)" "unprognostic (1.33e-1)" "unprognostic (6.74e-3)" "unprognostic (4.28e-3)" "prognostic unfavourable (5.79e-5)" "prognostic unfavourable (7.32e-5)" "unprognostic (1.68e-1)" "unprognostic (1.81e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.19e-3)" "unprognostic (4.48e-2)" 27.9 30.9 34.7 24.2 42.3 36.0 25.3 31.2 59.7 21.0 32.8 16.3 25.9 29.4 21.9 33.9 73.5 22.1 24.4 109.3 31.6 33.4 28.2 11.1 17.9 34.0 35.0 49.6 23.4 19.4 51.0 25.2 19.9 38.0 23.6 23.5 24.6 37.9 36.9 1296.2 28.4 21.5 30.1 22.7 17.4 24.4 9.2 18.9 18.5 26.6 189.8 29.0 36.8 27.7 61.1 142.9 165.7 166.3 50.5 93.2 217.0 138.7 104.6 31.5 101.2 48.3 55.1 100.7 84.0 87.6 85.7 107.2 73.9 107.0 94.6 137.8 84.8 106.0 63.1 183.2 62.9 41.6 83.0 77.4 83.9 163.2 75.4 112.5 83.1 75.5 64.7 96.2 64.7 63.1 66.6 62.5 90.8 197.9 68.4 93.0 78.3 88.2 102.1 50.6 211.5 106.7 79.0 63.1 44.4 52.4 221.1 78.4 94.0 76.3 75.0 126.6 50.5 69.0 90.8 123.5 84.3 86.6 235.6 109.3 99.9 106.7 164.0 130.3 70.2 156.8 79.1 61.1 76.8 72.5 142.9 55.5 73.8 70.3 165.7 50.5 166.3 53.8 93.2 217.0 34.7 42.3 31.2 59.7 31.6 33.4 35.0 49.6 38.0 18.9 ALDOA ENSG00000285043 "Aldolase, fructose-bisphosphate A" P04075 16 30053090-30070420 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Glycolysis Lyase "Cancer-related genes, Disease mutation, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA004177 Uncertain Supported Cytosol 1200000000 Cytosol "HPA004177: AB_1078128" 1.8 0.9 2.7 1.1 5.0 2.1 7.2 0.7 7.7 4.9 1.5 2.0 2.4 0.0 2.5 3.9 0.9 3.6 1.6 5.3 2.3 1.3 0.0 2.3 2.0 0.8 4.4 2.2 0.8 0.8 3.0 1.4 4.0 2.4 0.5 2.8 1.6 7.5 10.6 0.6 0.1 1.9 0.4 1.7 1.3 11.6 0.8 1.2 4.7 0.2 2.7 1.2 1.0 7.0 6.6 0.9 6.2 4.2 8.5 12.5 3.7 8.8 1.9 6.2 1.5 5.2 1.5 4.0 6.9 5.4 21.6 3.6 5.0 24.5 5.9 6.8 6.3 14.0 10.9 3.8 4.3 7.9 6.0 8.2 5.9 11.5 10.5 2.3 5.1 0.5 10.7 12.2 7.7 1.2 7.1 13.4 3.9 4.9 8.0 2.1 5.5 7.6 4.0 22.4 15.1 0.7 6.1 5.0 1.0 1.6 1.5 5.1 4.0 1.7 8.0 2.4 3.7 5.3 7.3 5.5 8.0 7.6 11.4 3.5 0.1 6.2 0.1 5.3 2.6 7.4 7.0 7.0 5.7 6.6 6.2 8.5 6.6 0.9 4.2 2.3 5.6 5.4 12.5 ALDOB ENSG00000136872 "Aldolase, fructose-bisphosphate B" P05062 9 101420578-101435823 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "intestine: 804.1;kidney: 253.1;liver: 598.8" "Cell line enhanced" "Detected in some" "BEWO: 14.1;NB-4: 13.2;RPMI-8226: 15.2;SH-SY5Y: 13.2" "Cancer enriched" "Detected in many" 31 "liver cancer: 1414.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA002198, CAB020827" Enhanced 930000000 "CAB020827: , HPA002198: AB_1078129" "unprognostic (6.58e-3)" "unprognostic (2.83e-1)" "unprognostic (1.43e-3)" "unprognostic (1.03e-1)" "unprognostic (8.10e-2)" "unprognostic (1.96e-2)" "unprognostic (1.44e-3)" "unprognostic (4.34e-2)" "unprognostic (4.57e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (7.48e-2)" "unprognostic (1.66e-2)" "unprognostic (2.02e-1)" "unprognostic (2.58e-1)" "unprognostic (5.19e-2)" "unprognostic (1.96e-2)" 0.1 0.1 0.1 0.6 0.1 0.0 0.1 0.1 0.2 0.1 334.5 0.2 0.2 145.9 0.2 0.6 0.1 0.1 5.7 0.1 0.1 0.1 253.1 598.8 0.1 0.1 0.1 0.1 0.1 18.3 0.0 0.4 0.1 0.4 0.1 0.0 0.2 0.2 0.1 0.1 0.1 804.1 0.1 0.1 0.2 1.5 0.3 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.3 0.0 2.9 1.4 0.0 0.4 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.4 0.0 3.5 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.2 13.2 0.2 0.0 0.2 3.1 15.2 0.0 0.0 2.5 13.2 1.5 0.0 0.0 0.0 0.1 0.7 0.0 0.7 5.3 0.2 0.4 0.2 1.6 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.4 0.1 ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28577264 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 166.7;heart muscle: 56.9" "Cell line enhanced" "Detected in many" "RPMI-8226: 62.2;U-266/70: 42.9" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" 280000000 "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavourable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavourable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" 26.0 9.4 86.7 4.8 78.9 7.5 9.8 100.1 166.7 3.8 5.3 17.4 0.3 7.0 4.4 4.6 7.1 3.9 4.4 56.9 64.6 54.3 3.3 26.2 4.6 6.5 69.9 51.4 12.8 1.6 4.7 2.3 2.1 98.1 6.0 5.6 16.5 4.2 6.1 1.7 12.5 15.0 4.6 34.4 6.7 8.7 4.6 23.4 0.0 2.1 0.5 10.0 3.4 3.5 12.2 4.6 8.8 4.1 13.7 20.5 8.8 7.4 0.5 3.5 14.4 7.2 7.4 0.7 3.8 8.6 2.9 18.1 4.3 0.7 3.5 4.6 3.4 9.7 2.3 23.6 5.5 3.0 2.2 6.7 2.7 7.4 6.8 2.4 7.8 6.8 3.3 0.3 5.9 1.3 4.6 18.8 2.5 3.5 2.8 8.1 5.4 3.9 2.4 0.4 62.2 0.4 1.0 9.2 16.4 2.2 17.7 0.1 9.6 5.5 0.9 0.3 1.4 0.5 0.6 42.9 12.3 2.6 28.1 7.0 0.5 0.1 3.5 1.4 11.4 4.1 16.2 12.2 15.6 9.2 4.6 11.5 20.5 15.1 8.8 13.7 2.3 2.2 19.5 8.8 86.7 78.9 100.1 78.5 64.6 54.3 69.9 51.4 98.1 23.4 ALG1 "CDG1K, HMAT1, HMT-1, Mat-1" ENSG00000033011 "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase" Q9BT22 16 5033960-5087379 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA060392 Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA060392: " "unprognostic (1.66e-2)" "unprognostic (5.18e-1)" "prognostic favourable (5.79e-4)" "unprognostic (1.55e-2)" "unprognostic (2.10e-2)" "unprognostic (3.22e-2)" "unprognostic (2.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (5.27e-2)" "unprognostic (1.02e-2)" "prognostic unfavourable (6.93e-4)" "unprognostic (2.58e-3)" "unprognostic (3.86e-2)" 11.0 22.2 8.7 10.8 12.8 6.6 12.8 9.3 18.8 13.7 16.4 14.9 10.1 14.7 12.1 17.0 11.7 12.4 14.3 8.1 8.8 10.4 18.9 31.6 9.9 12.7 10.5 6.5 10.1 27.9 21.5 13.6 10.7 14.6 10.8 17.2 15.5 20.6 12.0 7.3 9.1 12.8 12.1 9.4 16.2 16.5 19.4 11.4 16.0 15.0 8.7 14.5 12.1 8.7 20.7 24.3 7.8 23.3 20.9 26.5 31.7 6.4 17.6 4.4 8.3 17.0 10.1 8.2 14.5 20.4 19.0 19.0 14.5 23.9 13.7 12.5 18.5 17.4 12.1 14.3 12.9 11.2 13.8 7.7 14.6 29.9 13.9 13.4 13.5 12.3 10.9 14.9 9.4 11.3 9.6 18.0 14.1 17.5 8.6 16.5 16.8 10.1 16.0 6.1 38.2 11.8 7.0 7.5 7.6 15.5 24.3 8.3 15.8 11.0 10.8 8.8 8.2 45.0 12.1 13.1 15.8 9.3 7.3 14.4 12.5 3.3 23.3 7.8 26.5 21.6 23.1 19.8 22.9 25.4 24.3 20.7 21.0 23.7 1.5 20.9 21.2 21.2 21.6 31.7 8.7 12.8 9.3 18.8 8.8 10.4 10.5 6.5 14.6 11.4 ALG10 "ALG10A, DIE2, FLJ14751" ENSG00000139133 "ALG10, alpha-1,2-glucosyltransferase" Q5BKT4 12 34022281-34029694 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA043329: , HPA063387: " "unprognostic (1.71e-1)" "unprognostic (4.98e-2)" "unprognostic (3.16e-3)" "unprognostic (2.80e-2)" "unprognostic (9.23e-2)" "unprognostic (3.49e-2)" "unprognostic (5.88e-4)" "unprognostic (2.13e-1)" "unprognostic (1.73e-2)" "unprognostic (8.01e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "unprognostic (9.29e-2)" "unprognostic (8.99e-2)" "unprognostic (1.53e-1)" "unprognostic (2.43e-1)" "unprognostic (6.45e-2)" 6.2 7.0 2.7 5.4 5.9 6.9 6.9 4.0 5.5 5.3 4.6 3.8 3.6 3.4 10.3 5.5 6.0 6.2 3.7 4.6 2.6 2.9 4.6 5.7 5.4 6.7 4.1 1.7 7.1 7.8 7.5 6.1 7.2 3.5 5.8 4.1 8.7 9.0 4.4 4.6 5.1 5.0 4.0 3.5 6.1 5.1 8.0 3.6 17.2 6.2 3.0 9.8 5.8 4.8 2.7 1.8 4.5 2.7 2.1 3.8 1.6 4.5 5.3 3.5 5.8 4.2 3.3 12.4 4.4 4.1 4.7 8.6 7.8 11.0 6.9 6.4 2.2 6.9 6.6 5.6 6.5 11.0 6.3 6.3 5.7 3.1 1.7 9.2 6.7 3.6 3.3 10.1 7.7 3.1 9.6 11.6 3.9 6.2 5.9 5.1 13.0 6.8 5.3 12.6 7.0 2.6 6.8 3.1 2.5 7.6 3.2 5.5 7.8 2.5 6.8 6.6 9.8 8.8 5.5 6.3 11.4 13.3 4.6 3.7 5.2 0.0 2.7 4.5 1.9 1.2 3.0 2.5 2.6 1.1 1.8 2.7 3.1 3.8 0.4 2.1 1.2 1.8 3.0 1.6 2.7 5.9 4.0 5.5 2.6 2.9 4.1 1.7 3.5 3.6 ALG10B KCR1 ENSG00000175548 "ALG10B, alpha-1,2-glucosyltransferase" Q5I7T1 12 38316578-38329728 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA043329: , HPA063387: " "unprognostic (4.55e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "unprognostic (1.25e-1)" "unprognostic (1.79e-1)" "unprognostic (3.01e-1)" "unprognostic (4.43e-2)" "unprognostic (8.58e-2)" "unprognostic (7.40e-2)" "unprognostic (8.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.05e-2)" "unprognostic (1.91e-1)" "unprognostic (3.30e-3)" "unprognostic (2.63e-1)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" 8.2 8.5 4.3 4.9 7.0 6.6 9.1 5.3 7.2 6.1 4.4 5.4 9.5 4.2 8.5 6.7 6.9 6.4 6.0 5.8 5.0 2.7 5.9 6.6 6.5 7.3 6.6 4.8 8.7 9.6 8.7 7.8 11.6 4.3 6.1 4.5 10.5 9.3 9.7 5.8 7.7 6.5 4.6 4.5 7.5 6.4 8.9 5.0 10.5 7.4 5.6 6.6 7.7 6.8 3.6 2.6 2.0 2.0 1.4 4.1 1.2 5.0 4.7 6.2 6.2 3.2 5.8 6.4 4.0 2.1 5.4 4.8 1.7 15.4 7.7 7.0 2.0 5.3 5.4 4.4 7.8 5.1 6.9 8.2 8.1 3.5 3.5 10.9 5.8 3.2 5.8 7.6 5.6 3.9 9.1 4.7 4.5 3.8 7.2 8.6 7.8 4.7 2.4 13.4 6.1 4.6 6.3 1.8 6.5 7.1 2.4 4.9 10.7 4.4 3.3 5.7 6.6 5.0 5.0 3.7 9.5 12.3 4.8 7.6 7.2 1.2 1.5 2.0 1.1 2.0 2.2 1.8 1.1 1.8 1.1 3.6 2.2 2.7 0.6 1.4 1.4 2.6 4.1 1.2 4.3 7.0 5.3 7.2 5.0 2.7 6.6 4.8 4.3 5.0 ALG11 "CDG1P, KIAA0266" ENSG00000253710 "ALG11, alpha-1,2-mannosyltransferase" Q2TAA5 13 52012398-52029664 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047214 Approved "HPA047214: AB_10961640" "unprognostic (9.21e-2)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (3.04e-2)" "unprognostic (9.15e-3)" "unprognostic (1.69e-1)" "unprognostic (2.28e-1)" "unprognostic (8.97e-3)" "unprognostic (8.89e-3)" "unprognostic (7.47e-2)" "unprognostic (2.30e-4)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (6.03e-2)" "unprognostic (9.71e-3)" 14.7 16.9 11.9 9.6 16.2 14.2 13.8 11.8 17.7 13.9 11.9 12.6 15.9 9.8 15.2 13.0 12.6 12.9 11.3 12.2 13.4 9.5 17.3 20.9 11.5 9.3 13.5 11.5 13.1 15.6 18.4 18.4 19.5 15.7 13.5 13.9 11.4 17.6 13.7 13.0 13.7 15.6 14.2 16.6 11.6 13.1 12.2 12.3 13.8 19.6 7.0 10.3 14.7 11.2 10.4 14.4 14.6 14.1 8.7 13.3 6.4 4.9 6.9 12.1 12.1 10.9 10.7 10.6 13.3 11.2 10.2 8.9 9.4 12.1 9.8 3.6 11.4 10.5 12.5 8.8 13.9 11.6 9.4 23.5 7.5 8.5 10.5 19.7 23.6 9.8 13.2 9.4 11.2 9.1 13.4 9.6 12.4 4.5 9.6 7.3 12.5 5.8 12.4 8.7 6.0 10.1 9.8 5.1 9.4 10.2 9.4 8.3 11.5 11.5 13.0 9.4 7.7 9.7 9.6 5.4 7.6 13.0 6.2 7.4 15.5 14.6 7.4 9.8 11.3 6.0 11.2 8.0 10.2 10.5 8.3 10.4 13.1 13.3 4.1 8.7 14.1 14.4 9.8 6.4 11.9 16.2 11.8 17.7 13.4 9.5 13.5 11.5 15.7 12.3 ALG12 "CDG1G, ECM39" ENSG00000182858 "ALG12, alpha-1,6-mannosyltransferase" Q9BV10 22 49900229-49918458 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003076, HPA051665" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA003076: , HPA051665: " "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (4.39e-3)" "prognostic favourable (6.09e-4)" "unprognostic (2.29e-1)" "unprognostic (3.32e-2)" "unprognostic (4.27e-3)" "unprognostic (3.33e-2)" "unprognostic (1.46e-1)" "unprognostic (3.32e-2)" "unprognostic (1.42e-1)" "unprognostic (2.21e-1)" "prognostic favourable (3.60e-5)" "unprognostic (1.62e-2)" "unprognostic (3.00e-2)" "unprognostic (9.89e-3)" "unprognostic (6.32e-2)" 9.8 13.3 9.6 11.3 11.2 8.5 9.9 16.0 12.7 10.9 11.7 16.2 15.7 18.0 13.2 11.5 12.1 11.4 11.0 12.0 10.0 5.8 14.1 22.8 10.8 9.2 11.6 7.9 11.8 17.5 14.7 10.6 11.3 10.9 13.5 7.1 12.2 19.4 10.2 8.7 11.5 14.8 7.7 8.9 11.5 14.5 6.5 14.9 12.6 24.5 10.5 12.8 12.1 10.3 7.6 7.8 17.7 9.4 16.1 12.7 7.9 6.9 7.0 7.4 12.3 14.2 6.6 8.2 7.3 6.5 8.6 6.9 11.4 10.0 3.7 6.7 6.4 12.6 9.0 8.6 4.3 5.9 13.2 3.4 11.7 11.4 16.0 8.5 7.6 10.0 8.9 8.4 12.2 8.2 4.2 9.4 4.5 15.8 8.2 6.9 7.1 6.4 13.9 9.3 9.8 9.0 7.9 5.0 8.2 11.6 22.0 9.0 9.0 7.7 6.3 9.6 7.3 6.6 5.5 8.3 3.8 4.9 10.6 6.5 9.1 17.7 8.8 7.4 12.4 8.2 12.7 5.3 9.8 12.2 7.7 7.6 8.3 9.3 6.9 16.1 9.4 7.8 12.3 7.9 9.6 11.2 16.0 12.7 10.0 5.8 11.6 7.9 10.9 14.9 ALG13 "CDG1S, CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W" ENSG00000101901 "ALG13, UDP-N-acetylglucosaminyltransferase subunit" Q9NP73 X 111665811-111760649 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Glycosyltransferase, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002853 Approved "HPA002853: AB_1078131" "unprognostic (4.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (6.97e-2)" "unprognostic (6.14e-2)" "unprognostic (2.74e-1)" "unprognostic (6.55e-3)" "unprognostic (2.26e-2)" "unprognostic (3.39e-3)" "unprognostic (1.73e-2)" "unprognostic (4.62e-3)" "prognostic unfavourable (1.10e-6)" "unprognostic (1.19e-1)" "unprognostic (1.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.45e-2)" 20.6 23.0 18.4 23.2 23.2 19.3 24.8 20.9 25.5 21.1 23.3 21.6 22.0 18.0 26.3 28.5 18.3 22.5 22.2 16.8 16.6 16.2 23.5 31.1 19.7 28.4 22.4 16.1 24.2 18.8 13.0 41.7 18.7 19.5 26.7 26.5 16.3 19.5 25.6 11.2 25.2 25.7 23.5 21.6 31.4 20.1 19.0 20.3 23.6 24.5 14.6 25.8 18.3 20.9 10.2 14.4 21.7 12.5 3.4 11.1 7.1 11.5 13.1 11.8 7.5 7.7 11.0 6.7 9.5 9.8 12.2 15.1 13.2 12.2 10.1 18.2 13.1 6.7 14.0 6.6 12.9 7.2 9.4 5.5 14.9 14.9 11.4 10.1 22.3 13.1 12.5 9.8 21.2 13.2 12.3 29.1 12.1 29.5 8.5 9.1 10.8 18.1 6.6 7.5 14.0 19.5 18.0 7.1 10.5 13.5 8.2 8.2 7.3 9.7 8.9 10.6 5.3 13.6 18.1 14.0 23.2 16.2 11.3 13.4 8.0 21.7 12.4 12.2 7.8 12.5 7.6 8.4 8.9 7.6 14.4 10.2 11.1 9.1 2.5 3.4 9.4 7.5 10.7 7.1 18.4 23.2 20.9 25.5 16.6 16.2 22.4 16.1 19.5 20.3 ALG2 "CDG1I, CDGIi, FLJ14511, hALPG2, NET38" ENSG00000119523 "ALG2, alpha-1,3/1,6-mannosyltransferase" Q9H553 9 99216426-99221956 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041512, HPA041601" Approved Enhanced "Actin filaments,Cytosol" "Actin filaments, Cytosol" "HPA041512: AB_10794380, HPA041601: AB_10794302" "unprognostic (8.86e-3)" "unprognostic (4.39e-1)" "unprognostic (2.37e-1)" "prognostic favourable (8.44e-5)" "unprognostic (9.21e-3)" "prognostic unfavourable (1.56e-4)" "unprognostic (1.06e-2)" "unprognostic (5.94e-2)" "unprognostic (3.31e-1)" "unprognostic (3.66e-1)" "unprognostic (2.99e-2)" "unprognostic (1.08e-1)" "prognostic favourable (2.28e-7)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-2)" "unprognostic (4.81e-1)" 12.5 28.0 9.2 9.4 9.7 10.5 16.4 13.1 12.5 18.8 12.9 11.6 31.1 11.0 15.2 39.2 12.3 15.8 13.9 12.1 8.3 9.5 24.8 45.5 16.0 12.8 10.8 6.5 18.4 43.4 14.7 22.4 22.5 12.0 16.7 14.9 14.7 24.1 32.6 13.3 8.7 15.5 12.6 11.3 15.9 15.0 12.6 9.7 14.8 26.0 9.9 15.8 12.9 11.8 16.8 41.0 18.2 18.5 17.5 26.4 17.8 8.1 11.0 8.1 11.6 30.1 19.6 16.7 16.7 26.6 17.1 14.9 13.1 11.8 8.8 7.8 19.2 32.3 13.7 17.9 17.2 13.3 6.3 5.2 8.7 19.4 36.2 9.2 9.9 21.4 23.4 14.5 26.4 19.1 9.1 19.9 15.8 17.1 4.6 10.9 10.5 15.5 5.4 16.5 13.7 22.9 10.4 8.7 7.1 12.3 22.7 21.5 9.2 7.8 13.6 11.7 11.6 14.9 10.4 18.7 10.1 3.8 22.0 7.3 5.7 18.2 18.5 11.2 18.6 14.6 26.4 16.8 17.7 18.4 23.0 13.3 15.4 15.0 5.0 17.5 12.9 41.0 18.8 17.8 9.2 9.7 13.1 12.5 8.3 9.5 10.8 6.5 12.0 9.7 ALG3 "CDGS4, D16Ertd36e, Not56, NOT56L" ENSG00000214160 "ALG3, alpha-1,3- mannosyltransferase" Q92685 3 184242301-184249548 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045103 Approved "HPA045103: AB_10960547" "unprognostic (3.63e-2)" "unprognostic (2.60e-1)" "unprognostic (2.36e-2)" "unprognostic (1.80e-3)" "unprognostic (3.63e-1)" "unprognostic (7.93e-3)" "prognostic unfavourable (1.58e-5)" "prognostic unfavourable (8.67e-5)" "unprognostic (6.18e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-3)" "unprognostic (6.15e-2)" "prognostic unfavourable (1.25e-4)" "unprognostic (9.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-1)" "unprognostic (5.02e-2)" 14.2 24.1 7.7 12.2 10.3 11.6 15.4 7.2 12.9 11.5 15.5 13.7 15.2 14.3 12.8 11.2 20.5 11.5 15.4 13.0 7.3 6.5 19.7 74.4 12.9 16.8 11.5 7.3 12.7 37.7 18.4 11.7 26.6 10.2 14.0 16.0 12.4 20.9 13.7 18.9 18.4 16.3 14.0 7.9 14.9 15.0 20.8 10.1 13.9 15.9 14.9 18.8 17.4 15.8 14.2 30.1 6.0 25.4 18.7 18.0 15.5 20.3 17.7 4.8 16.3 19.6 11.2 16.5 11.0 12.5 15.1 12.9 27.1 13.7 17.9 30.0 13.5 24.6 17.5 23.8 9.4 12.9 20.3 16.1 13.6 21.8 18.0 26.0 14.5 13.3 20.0 17.8 25.1 8.2 15.8 36.3 9.7 25.0 12.6 21.1 15.3 23.2 13.1 7.5 71.2 16.9 6.8 12.2 10.3 10.2 40.3 17.5 38.2 14.8 6.5 16.0 10.0 13.9 23.4 19.9 34.9 19.0 14.3 34.2 14.3 0.2 25.4 6.0 16.0 25.0 18.0 14.2 17.3 16.2 30.1 12.3 15.6 15.1 0.9 18.7 19.7 27.4 18.0 15.5 7.7 10.3 7.2 12.9 7.3 6.5 11.5 7.3 10.2 10.1 ALG5 bA421P11.2 ENSG00000120697 "ALG5, dolichyl-phosphate beta-glucosyltransferase" Q9Y673 13 36949775-37000261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007989 Approved Approved Cytosol Cytosol "HPA007989: AB_1078132" "unprognostic (1.87e-1)" "unprognostic (1.73e-2)" "unprognostic (6.07e-2)" "unprognostic (1.05e-3)" "unprognostic (3.01e-1)" "prognostic unfavourable (2.11e-4)" "unprognostic (1.57e-2)" "unprognostic (5.82e-2)" "unprognostic (5.21e-2)" "unprognostic (7.46e-2)" "unprognostic (3.51e-2)" "unprognostic (3.30e-1)" "prognostic favourable (1.40e-5)" "unprognostic (7.44e-2)" "unprognostic (1.66e-1)" "unprognostic (7.14e-3)" "unprognostic (1.86e-1)" 14.7 18.2 11.8 14.0 14.2 11.3 19.9 10.9 13.7 16.7 16.5 10.3 34.2 13.0 13.5 34.8 11.7 12.4 12.9 13.1 10.0 10.5 18.1 36.7 19.1 28.0 16.1 12.8 11.8 60.4 11.8 11.6 17.0 12.1 12.9 20.8 7.3 30.2 37.0 9.0 11.0 12.6 10.9 15.1 12.9 17.6 7.2 14.2 15.4 25.5 12.1 12.4 12.4 11.1 19.1 45.5 17.7 24.8 22.1 25.2 26.9 10.6 14.3 13.3 13.6 36.6 24.5 9.8 29.6 31.5 25.1 20.5 28.1 37.2 15.3 12.3 17.9 26.4 16.3 22.6 23.4 16.4 32.1 35.3 12.0 17.6 35.8 29.9 18.5 25.7 33.3 20.0 26.8 19.1 16.1 19.2 22.6 19.1 20.1 23.9 13.6 11.7 24.6 16.4 37.6 26.6 20.2 10.6 20.6 12.5 23.2 17.1 14.0 29.7 14.5 14.1 8.0 15.4 18.8 16.4 12.6 20.1 21.7 19.0 23.2 17.7 24.1 10.0 24.4 24.8 24.6 19.1 23.0 24.4 23.6 17.0 21.2 23.2 2.7 22.1 20.2 45.5 25.2 26.9 11.8 14.2 10.9 13.7 10.0 10.5 16.1 12.8 12.1 14.2 ALG6 ENSG00000088035 "ALG6, alpha-1,3-glucosyltransferase" Q9Y672 1 63367590-63438562 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062536 Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA062536: " "unprognostic (1.21e-1)" "unprognostic (5.60e-3)" "prognostic favourable (4.86e-4)" "unprognostic (1.59e-1)" "unprognostic (3.45e-1)" "unprognostic (2.45e-2)" "prognostic unfavourable (9.46e-4)" "unprognostic (2.07e-1)" "unprognostic (9.81e-3)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (3.90e-2)" "prognostic unfavourable (2.63e-6)" "unprognostic (1.84e-3)" "unprognostic (1.07e-1)" "unprognostic (4.61e-2)" "unprognostic (3.41e-1)" 9.7 13.7 9.3 13.5 13.5 8.8 11.6 12.2 12.6 9.9 11.8 10.1 9.0 12.1 11.0 14.3 16.7 9.6 9.1 9.9 11.2 7.1 10.3 14.6 10.0 13.4 8.2 11.1 10.8 11.5 10.6 10.0 14.1 11.6 8.9 14.0 10.2 12.9 11.9 8.0 13.7 13.5 7.5 10.5 14.5 10.0 6.9 8.7 25.9 9.7 8.5 21.7 10.0 11.6 7.5 7.9 24.2 7.4 7.4 10.6 5.6 5.3 4.8 8.5 7.8 10.2 8.8 11.2 6.3 2.2 3.3 3.8 5.6 5.4 13.9 15.2 5.2 10.3 12.4 10.1 6.0 15.6 9.8 10.7 5.5 4.6 5.0 12.7 9.3 7.3 6.1 8.1 3.0 12.5 11.3 11.2 7.7 7.0 12.2 10.7 26.0 7.2 12.5 12.0 16.4 9.5 7.4 7.9 4.3 16.8 17.5 16.5 9.7 7.2 6.8 5.5 5.5 11.6 8.1 9.5 13.3 11.5 5.3 12.7 18.4 24.2 7.4 13.6 8.8 6.6 10.6 7.5 7.2 8.5 7.9 5.6 8.7 9.1 4.3 7.4 6.4 6.5 9.4 5.6 9.3 13.5 12.2 12.6 11.2 7.1 8.2 11.1 11.6 8.7 ALG8 MGC2840 ENSG00000159063 "ALG8, alpha-1,3-glucosyltransferase" Q9BVK2 11 78100936-78139660 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051898 Approved Approved Nucleoplasm Nucleoplasm "HPA051898: " "unprognostic (1.37e-1)" "unprognostic (9.24e-2)" "unprognostic (4.60e-2)" "unprognostic (2.69e-2)" "unprognostic (2.65e-1)" "unprognostic (6.49e-2)" "unprognostic (5.38e-3)" "unprognostic (5.91e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (5.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.34e-1)" "unprognostic (3.78e-2)" "unprognostic (6.37e-2)" 20.2 24.5 18.0 11.2 22.3 9.7 23.7 13.8 17.9 16.5 15.0 20.7 23.9 10.3 14.5 30.9 13.3 18.4 12.3 13.0 15.9 16.0 24.9 40.8 12.8 15.7 16.0 11.6 22.9 23.4 24.2 23.6 21.7 17.1 15.5 19.0 17.6 23.2 19.5 8.2 13.3 13.3 14.8 17.6 13.8 13.1 38.9 16.5 18.2 29.7 13.1 17.4 13.2 11.2 21.9 19.4 3.0 20.3 18.2 19.0 14.9 9.3 25.9 24.9 21.2 21.5 15.2 13.4 13.8 20.7 23.7 23.0 49.0 34.4 22.0 25.6 16.5 27.1 28.9 19.9 38.3 15.8 17.4 26.5 22.8 22.0 14.0 25.3 17.6 12.1 12.8 27.6 13.8 17.2 32.8 22.7 31.6 13.7 21.1 28.5 27.6 13.6 22.5 11.4 52.3 23.8 14.5 7.3 18.3 19.9 32.3 10.0 36.0 20.0 10.5 16.1 18.7 36.2 11.9 16.3 31.6 32.5 8.9 24.8 27.8 0.3 17.5 3.0 15.7 19.5 17.5 21.9 16.0 16.1 19.4 16.6 19.0 17.2 1.1 18.2 20.3 18.7 13.0 14.9 18.0 22.3 13.8 17.9 15.9 16.0 16.0 11.6 17.1 16.5 ALG9 DIBD1 ENSG00000086848 "ALG9, alpha-1,2-mannosyltransferase" Q9H6U8 11 111782195-111871581 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA038575 Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA038575: AB_10672718" "unprognostic (1.48e-1)" "unprognostic (5.39e-2)" "unprognostic (6.22e-2)" "unprognostic (5.34e-3)" "unprognostic (8.72e-2)" "unprognostic (2.90e-1)" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (7.07e-3)" "unprognostic (5.11e-2)" "unprognostic (8.75e-3)" "unprognostic (1.52e-2)" "prognostic unfavourable (7.29e-5)" "unprognostic (9.15e-2)" "unprognostic (7.76e-2)" "unprognostic (4.20e-2)" "unprognostic (1.10e-2)" 19.9 13.5 11.8 11.4 17.9 9.0 16.8 19.3 19.3 16.9 13.7 15.6 15.7 16.2 19.1 15.7 13.8 12.5 14.0 14.3 11.6 13.7 13.7 17.7 12.3 13.5 12.2 11.2 19.2 29.9 21.0 16.5 20.3 14.6 14.7 14.9 17.5 34.3 20.1 11.7 17.3 13.2 15.8 13.2 13.0 14.1 25.0 9.8 15.3 17.4 10.9 15.2 13.8 14.2 7.8 9.5 7.0 7.9 7.1 12.2 6.5 9.7 9.8 19.3 18.9 12.0 11.5 14.7 12.7 10.3 10.5 11.4 16.8 16.6 15.7 18.1 14.2 18.3 10.1 15.3 14.9 12.1 7.9 11.9 5.8 12.3 14.0 13.4 8.3 10.0 10.4 11.0 10.9 10.1 11.9 24.6 17.2 7.2 13.4 11.9 6.4 10.9 12.3 17.2 30.6 11.6 8.7 9.5 16.3 11.2 17.1 6.8 18.5 5.5 9.9 22.2 15.6 10.7 13.6 8.0 6.0 14.8 9.2 16.7 15.0 6.7 5.8 7.0 8.5 7.9 9.4 7.8 8.0 8.8 9.5 6.6 12.2 7.3 2.3 7.1 6.9 9.4 7.7 6.5 11.8 17.9 19.3 19.3 11.6 13.7 12.2 11.2 14.6 9.8 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921566 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.1;pituitary gland: 17.9" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 26.4" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 1.8 3.1 3.6 1.2 4.4 0.3 1.1 0.5 8.1 0.7 2.1 2.0 0.0 0.7 0.5 0.5 0.6 0.5 1.2 0.4 3.4 4.9 0.4 0.5 1.1 0.5 2.7 4.2 0.6 0.4 0.4 17.9 0.5 5.5 0.5 1.2 2.4 0.9 0.8 0.3 0.9 1.5 0.9 2.1 0.5 0.8 4.9 0.9 0.0 1.6 0.0 0.3 0.6 1.2 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 3.5 0.0 0.0 0.1 0.3 26.4 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.0 4.0 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.6 4.4 0.5 5.9 3.4 4.9 2.7 4.2 5.5 0.9 ALKBH1 "ABH, alkB, ALKBH, hABH" ENSG00000100601 "AlkB homolog 1, histone H2A dioxygenase" Q13686 14 77672404-77708020 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, RNA repair, Translation regulation" "Dioxygenase, Lyase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044087, HPA060061" Approved Supported "Nucleoplasm,Endoplasmic reticulum" "Intracellular and membrane" Nucleoplasm "Endoplasmic reticulum" "HPA044087: , HPA060061: " "unprognostic (1.92e-2)" "unprognostic (8.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-3)" "unprognostic (3.41e-2)" "unprognostic (5.03e-2)" "unprognostic (3.74e-3)" "unprognostic (7.45e-3)" "unprognostic (2.68e-2)" "unprognostic (3.95e-2)" "unprognostic (5.05e-3)" "unprognostic (2.16e-2)" "prognostic favourable (1.80e-4)" "unprognostic (1.65e-3)" "unprognostic (1.46e-1)" "unprognostic (2.63e-1)" "unprognostic (2.44e-2)" 8.2 8.5 6.2 6.7 8.6 2.7 9.7 9.6 8.8 9.7 9.1 8.2 4.5 6.5 7.0 5.9 7.1 8.0 5.8 11.1 5.4 5.7 7.9 9.4 5.9 8.3 6.5 3.7 8.3 7.9 8.4 11.2 10.2 6.4 9.3 9.1 9.9 7.2 8.7 16.5 8.2 6.7 7.8 5.5 8.3 7.8 9.9 6.6 12.7 8.8 6.5 10.3 8.5 9.4 5.4 4.9 11.4 5.7 5.2 5.3 3.2 5.2 7.8 6.4 4.3 6.9 7.5 8.0 5.5 7.2 12.2 13.7 7.9 3.2 8.1 3.1 5.0 4.8 13.9 5.9 14.4 5.5 5.4 4.3 4.6 6.6 9.7 4.5 2.8 6.4 9.9 7.1 11.3 9.9 6.6 4.7 6.5 8.3 6.0 5.9 7.0 10.1 6.1 6.5 5.4 7.0 4.7 8.2 6.1 4.5 4.7 5.9 11.6 4.7 4.5 5.1 5.2 5.6 4.4 5.9 9.3 7.9 3.4 6.5 5.0 11.4 5.0 2.2 5.0 5.7 4.3 5.4 4.7 5.0 4.9 4.9 5.0 3.9 1.4 5.2 3.8 2.6 5.3 3.2 6.2 8.6 9.6 8.8 5.4 5.7 6.5 3.7 6.4 6.6 ALKBH2 "ABH2, MGC90512" ENSG00000189046 "AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase" Q6NS38 12 109088188-109093631 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011198, HPA045392, HPA051976" Approved Enhanced Nucleoplasm Nucleoplasm "CAB011198: AB_261971, HPA045392: , HPA051976: " "prognostic favourable (6.67e-5)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (4.64e-2)" "unprognostic (4.55e-2)" "unprognostic (4.71e-2)" "unprognostic (1.69e-1)" "unprognostic (9.60e-2)" "unprognostic (3.63e-1)" "unprognostic (1.85e-1)" "unprognostic (6.39e-2)" "unprognostic (6.43e-3)" "prognostic unfavourable (1.41e-5)" "unprognostic (1.01e-2)" "unprognostic (7.88e-2)" "unprognostic (6.24e-2)" "prognostic favourable (8.67e-4)" 16.1 12.3 13.6 16.9 13.4 8.2 22.3 12.7 20.5 12.9 11.7 15.2 14.6 9.0 18.0 14.2 14.1 18.3 12.2 12.3 13.5 12.3 12.0 25.6 9.8 17.0 14.3 8.9 23.1 18.5 7.1 7.8 8.1 15.7 15.0 10.7 10.8 18.9 18.5 20.0 25.0 10.7 15.9 15.4 12.3 12.6 14.3 13.5 11.3 13.9 19.7 16.5 15.5 13.8 16.9 13.1 1.1 6.7 9.0 18.2 6.9 12.9 22.2 12.7 28.4 9.0 12.2 20.2 8.6 5.8 9.1 10.3 23.4 9.3 20.0 8.6 5.0 9.5 21.3 8.7 5.4 17.7 19.0 10.0 12.6 21.3 11.9 13.7 9.3 12.5 18.9 8.6 22.2 3.5 14.7 12.0 6.1 22.8 12.6 27.6 17.6 22.6 11.2 12.4 21.5 12.1 18.1 13.1 22.6 9.2 29.7 18.0 18.3 8.5 3.6 10.2 11.1 9.6 12.7 16.8 19.4 43.5 8.7 11.9 16.3 1.1 5.1 0.7 8.0 6.7 14.1 16.2 12.1 11.2 5.1 16.9 18.2 10.7 0.9 9.0 4.3 13.1 9.0 6.9 13.6 13.4 12.7 20.5 13.5 12.3 14.3 8.9 15.7 13.5 ALKBH3 DEPC-1 ENSG00000166199 "AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase" Q96Q83 11 43880811-43920266 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009674, HPA046489" Approved Supported Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA009674: AB_1850460, HPA046489: " "unprognostic (3.53e-1)" "unprognostic (2.41e-1)" "unprognostic (7.43e-3)" "unprognostic (4.70e-2)" "unprognostic (6.94e-3)" "unprognostic (1.89e-1)" "unprognostic (7.71e-2)" "unprognostic (5.42e-2)" "unprognostic (8.56e-2)" "unprognostic (4.62e-1)" "unprognostic (5.87e-2)" "unprognostic (7.02e-2)" "unprognostic (2.09e-2)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (2.76e-1)" "unprognostic (1.35e-2)" 17.6 14.2 14.3 13.2 16.7 8.6 26.5 21.2 22.7 19.1 15.7 19.5 12.8 13.2 22.6 31.2 16.2 20.0 16.4 12.5 14.3 13.4 15.6 25.8 15.1 17.3 15.0 14.4 21.8 23.5 22.1 16.6 9.1 15.6 19.1 16.6 19.5 25.5 19.1 29.1 20.2 15.0 18.3 14.8 17.8 17.0 17.3 12.1 14.5 16.4 21.4 22.2 15.2 17.4 14.9 18.5 21.2 21.0 17.1 21.3 13.8 7.4 12.9 5.1 0.0 10.0 12.9 0.0 9.0 20.0 18.1 17.8 6.0 5.7 1.1 5.7 13.6 10.1 7.0 15.6 16.9 0.0 24.7 10.8 8.7 12.6 24.9 19.8 14.5 13.6 27.1 8.0 39.1 13.0 15.3 11.8 9.0 8.8 17.8 10.2 9.4 19.0 5.2 11.1 13.9 10.9 11.6 9.7 7.8 7.0 11.0 16.5 15.9 12.2 9.1 10.3 5.7 16.8 12.9 10.7 11.2 12.0 15.3 8.4 8.4 21.2 12.9 7.1 17.0 14.1 16.2 14.4 17.4 15.1 18.5 14.9 21.3 18.9 2.3 17.1 21.0 16.3 16.2 13.8 14.3 16.7 21.2 22.7 14.3 13.4 15.0 14.4 15.6 12.1 ALKBH8 "MGC10235, TRM9, TRMT9A" ENSG00000137760 "AlkB homolog 8, tRNA methyltransferase" Q96BT7 11 107502726-107565746 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Multifunctional enzyme, Oxidoreductase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038724, HPA038725, HPA061514" Approved Supported "Nucleoplasm,Nuclear bodies" "Nuclear bodies" Nucleoplasm "HPA038724: , HPA038725: AB_10674838, HPA061514: " "unprognostic (2.66e-2)" "unprognostic (3.82e-1)" "unprognostic (8.19e-2)" "unprognostic (3.76e-1)" "unprognostic (4.04e-2)" "unprognostic (2.97e-1)" "unprognostic (1.22e-2)" "unprognostic (1.95e-1)" "unprognostic (4.45e-2)" "unprognostic (7.67e-2)" "unprognostic (1.89e-2)" "unprognostic (7.95e-2)" "unprognostic (2.81e-1)" "unprognostic (2.03e-1)" "unprognostic (2.04e-1)" "unprognostic (2.34e-3)" "unprognostic (1.01e-1)" 9.7 6.7 7.2 14.1 12.6 6.1 11.3 9.9 11.7 8.6 7.4 7.6 9.4 6.7 9.5 7.1 9.8 7.4 6.0 12.4 7.4 7.6 9.2 9.5 7.5 11.5 7.2 5.5 9.9 7.0 13.4 10.0 6.9 7.9 8.9 7.9 8.1 7.7 7.5 12.6 9.7 7.8 9.0 7.0 10.8 6.8 5.8 5.8 9.2 11.1 5.7 12.0 8.9 8.1 3.7 3.3 0.5 4.1 4.8 6.2 2.2 4.9 6.0 6.3 6.8 3.5 7.7 5.1 9.5 7.0 7.0 7.6 11.1 9.0 11.5 5.5 9.1 8.9 9.3 7.6 9.2 10.3 6.1 9.6 2.3 5.1 5.2 12.2 11.9 4.7 8.7 9.0 11.5 8.7 13.6 3.9 5.5 4.4 11.0 6.2 8.2 9.9 10.1 9.7 8.0 5.6 5.4 5.7 6.3 5.4 4.1 4.0 6.8 3.7 8.1 15.3 9.2 5.0 11.8 3.6 3.8 9.0 4.3 8.3 15.0 0.0 2.0 0.5 4.5 4.1 4.3 1.9 3.3 3.9 3.3 3.7 6.2 5.2 0.0 4.8 2.7 2.0 3.5 2.2 7.2 12.6 9.9 11.7 7.4 7.6 7.2 5.5 7.9 5.8 ALOX12 12S-LOX ENSG00000108839 "Arachidonate 12-lipoxygenase, 12S type" P18054 17 6996065-7010736 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Hydrolase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 28.6;esophagus: 28.4;tongue: 22.7;vagina: 42.7" "Group enriched" "Detected in some" 5 "A-431: 17.1;HEL: 27.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "neutrophil: 4.8" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in single" 5 "olfactory region: 5.4" "HPA010691, CAB019287, HPA064819" Enhanced Supported "Nuclear speckles,Cytosol" 5800000 Cytosol "Nuclear speckles" "CAB019287: , HPA010691: AB_1844756, HPA064819: " "unprognostic (3.61e-3)" "unprognostic (6.93e-2)" "unprognostic (7.17e-5)" "unprognostic (9.43e-2)" "unprognostic (6.06e-2)" "unprognostic (2.25e-3)" "unprognostic (2.45e-1)" "unprognostic (3.16e-1)" "unprognostic (3.02e-2)" "unprognostic (1.59e-2)" "unprognostic (3.96e-5)" "unprognostic (4.01e-3)" "unprognostic (2.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.87e-1)" "unprognostic (5.90e-2)" "unprognostic (3.47e-2)" 0.3 0.6 0.3 1.5 0.4 2.0 0.3 0.3 1.0 28.6 0.4 0.3 0.3 0.7 3.4 0.5 28.4 0.4 1.6 0.8 0.3 0.1 0.3 0.3 0.5 1.9 0.5 0.3 0.4 0.8 0.0 0.3 0.7 0.4 0.3 0.0 0.4 8.1 0.3 0.5 12.8 0.8 0.3 0.3 1.5 0.3 0.6 0.3 0.3 0.8 22.7 9.5 1.2 42.7 1.1 1.3 4.8 0.9 0.7 0.8 14.3 17.1 2.9 1.3 1.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 2.5 0.6 0.8 0.6 0.0 2.2 0.0 0.1 0.0 1.8 2.2 27.4 3.8 1.8 0.1 0.2 4.5 0.0 0.0 0.0 0.0 0.0 1.8 0.9 0.0 0.2 0.3 0.6 0.9 0.6 0.9 0.5 0.4 0.0 2.2 0.1 0.6 0.5 0.5 0.2 1.0 0.7 3.2 1.5 0.8 1.4 0.7 0.5 0.2 0.5 0.8 2.0 0.7 1.8 0.9 1.7 0.7 0.5 0.5 1.1 0.5 0.8 0.7 0.7 0.2 0.4 4.8 0.7 0.4 1.3 0.3 14.3 0.3 0.4 0.3 0.6 0.3 0.1 0.5 0.3 0.4 0.3 ALOX15 15-LOX-1 ENSG00000161905 "Arachidonate 15-lipoxygenase" P16050 17 4630902-4642294 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 27.9;blood: 89.8;lung: 24.4" "Group enriched" "Detected in some" 7 "HMC-1: 16.1;MCF7: 14.0;T-47d: 4.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 183 "eosinophil: 89.8" "Lineage enriched" "Detected in single" 183 "granulocytes: 89.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004962, CAB004963, HPA013859" Approved "CAB004962: , CAB004963: , HPA013859: AB_1844758" "unprognostic (5.31e-4)" "unprognostic (1.43e-2)" "unprognostic (2.81e-2)" "unprognostic (8.36e-3)" "unprognostic (2.22e-1)" "unprognostic (8.60e-2)" "unprognostic (2.36e-1)" "unprognostic (2.66e-2)" "unprognostic (1.70e-2)" "unprognostic (1.84e-2)" "unprognostic (2.51e-2)" "unprognostic (3.77e-1)" "unprognostic (1.31e-3)" "unprognostic (1.88e-2)" "unprognostic (1.30e-1)" "unprognostic (2.78e-1)" "unprognostic (1.59e-1)" 27.9 0.1 0.2 4.5 1.1 0.2 4.2 0.2 0.3 0.5 2.8 0.2 0.2 1.9 0.2 8.1 0.4 14.4 1.5 2.7 0.3 0.4 0.2 1.7 24.4 1.7 0.5 0.2 3.0 0.2 0.0 6.3 1.5 0.4 0.3 0.9 0.2 1.0 0.2 0.2 2.2 3.7 0.5 0.7 1.1 1.0 1.4 0.4 2.0 0.2 0.2 0.4 1.9 0.2 0.0 0.4 89.8 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.1 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 0.0 0.3 1.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 89.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 1.1 0.2 0.3 0.3 0.4 0.5 0.2 0.4 0.4 ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase, type B" O15296 17 8039017-8049134 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 57.4;esophagus: 30.6;lung: 44.0;prostate: 35.9" "Cell line enhanced" "Detected in some" "HHSteC: 6.0;HSkMC: 12.7;hTCEpi: 26.2" "Cancer enhanced" "Detected in all" "prostate cancer: 91.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "classical monocyte: 6.1;myeloid DC: 6.8" "Group enriched" "Detected in many" 9 "dendritic cells: 6.8;monocytes: 6.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA010562: " "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (2.56e-1)" "unprognostic (2.28e-3)" "unprognostic (1.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.59e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.49e-2)" 8.9 0.6 0.4 0.7 0.6 0.3 57.4 0.1 0.4 7.6 4.6 0.1 0.0 0.2 0.3 0.7 30.6 0.8 0.5 0.2 1.3 0.0 2.9 0.7 44.0 7.1 1.8 0.3 0.8 0.8 0.2 0.9 0.7 1.3 35.9 0.3 0.1 3.6 0.2 0.3 15.4 1.9 0.2 4.1 3.1 1.6 1.0 2.0 0.5 0.8 6.6 4.1 1.1 12.9 0.0 6.8 0.2 6.1 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 12.7 26.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.2 0.7 0.0 0.2 0.0 1.7 0.4 0.6 0.1 0.4 1.3 0.0 1.8 0.3 1.3 2.0 ALOX5 5-LOX ENSG00000012779 "Arachidonate 5-lipoxygenase" P09917 10 45374176-45446119 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Leukotriene biosynthesis" "Dioxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 45.2;bone marrow: 39.9;lymphoid tissue: 41.8" "Cell line enhanced" "Detected in some" "BEWO: 7.8;Daudi: 21.8;HMC-1: 15.6;Karpas-707: 6.9;RT4: 10.2;U-266/70: 10.3;U-698: 7.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071285 Enhanced Supported Nucleoplasm Nucleoplasm "HPA071285: " "unprognostic (2.57e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.75e-2)" "unprognostic (7.98e-3)" "unprognostic (1.26e-1)" "unprognostic (5.32e-2)" "unprognostic (8.69e-2)" "unprognostic (1.86e-2)" "unprognostic (6.91e-2)" "unprognostic (5.04e-2)" "unprognostic (3.42e-1)" "prognostic unfavourable (1.80e-5)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "prognostic favourable (7.18e-4)" 7.4 3.9 2.9 18.3 7.4 39.9 5.8 13.2 3.2 3.4 6.5 6.4 1.0 4.5 3.2 4.7 4.9 5.4 8.0 6.1 3.9 2.6 4.8 2.6 34.7 36.9 9.0 1.7 2.6 10.0 1.3 1.7 11.2 6.1 7.8 3.4 3.2 6.6 3.4 1.1 2.9 14.4 7.8 8.4 41.8 4.5 2.0 6.2 2.4 3.0 1.4 16.7 27.2 10.5 14.8 11.1 45.2 21.3 0.0 0.5 9.5 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 6.0 21.8 0.7 0.0 0.3 0.2 0.0 0.0 0.4 0.2 4.2 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.8 0.2 10.2 0.5 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 1.2 0.0 0.0 10.3 1.9 7.2 0.0 0.1 0.0 36.7 21.3 27.0 0.0 20.0 0.1 14.8 0.5 0.2 11.1 10.4 0.0 0.0 45.2 0.0 19.6 0.3 0.1 9.5 2.9 7.4 13.2 3.2 3.9 2.6 9.0 1.7 6.1 6.2 ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "skin 1: 30.2" "Cell line enhanced" "Detected in some" "A-431: 6.5;HBEC3-KT: 10.6;hTCEpi: 7.8;hTERT-HME1: 14.8;T-47d: 4.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.9" "Group enriched" "Detected in many" 8 "basal ganglia: 1.1;cerebellum: 1.4;cerebral cortex: 2.3;pons and medulla: 1.1" "Group enriched" "Detected in some" 5 "gdT-cell: 1.0;naive CD4 T-cell: 2.7" "Lineage enriched" "Detected in single" 28 "T-cells: 2.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: " "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" 0.1 0.0 0.1 0.1 1.1 0.0 1.6 1.4 2.3 1.2 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 1.1 0.1 0.0 0.1 0.1 0.1 0.1 30.2 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 1.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 2.7 0.2 6.5 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.1 0.4 0.1 0.5 0.2 0.2 0.1 0.4 0.9 10.6 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.8 0.1 14.8 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.7 0.0 4.7 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.1 1.4 2.3 0.1 0.1 0.1 0.1 1.1 0.1 ALPI ENSG00000163295 "Alkaline phosphatase, intestinal" P09923 2 232456123-232460032 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 406 "intestine: 133.2" "Cell line enriched" "Detected in some" 12 "CACO-2: 12.4" "Cancer enhanced" "Detected in many" "liver cancer: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" "Plasma membrane" "HPA038764: , HPA038765: , HPA051699: " "unprognostic (1.01e-1)" "unprognostic (7.71e-2)" "unprognostic (4.14e-2)" "unprognostic (1.47e-1)" "unprognostic (9.57e-4)" "unprognostic (8.07e-2)" "unprognostic (1.71e-1)" "unprognostic (9.99e-2)" 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 63.0 0.0 0.0 57.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.0 0.1 0.1 133.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 ALPK1 "FLJ22670, KIAA1527, Lak" ENSG00000073331 "Alpha kinase 1" Q96QP1 4 112285509-112442620 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA027435, HPA027443" Approved Approved Centrosome Centrosome "HPA027435: AB_10599614, HPA027443: AB_10599421" "unprognostic (6.24e-2)" "unprognostic (1.92e-1)" "unprognostic (9.30e-2)" "unprognostic (1.69e-2)" "unprognostic (7.40e-2)" "unprognostic (5.45e-2)" "unprognostic (2.55e-2)" "unprognostic (7.47e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-1)" "unprognostic (7.14e-2)" "unprognostic (2.78e-1)" "prognostic unfavourable (5.82e-7)" "unprognostic (1.60e-1)" "unprognostic (4.17e-2)" "unprognostic (2.81e-1)" "prognostic favourable (1.17e-4)" 15.1 10.6 5.3 8.3 7.7 17.3 9.3 1.3 5.9 10.8 9.5 5.8 3.0 4.5 9.8 9.2 8.8 9.2 7.5 6.1 6.1 2.3 10.8 13.4 13.2 11.4 9.7 1.0 17.4 9.7 11.0 14.0 11.5 6.6 14.0 7.8 9.6 10.4 6.8 5.0 11.8 12.1 11.3 16.6 16.2 7.4 4.2 8.5 13.7 12.4 4.7 13.7 13.6 11.6 0.9 3.2 16.3 4.3 0.4 0.8 1.2 1.6 5.0 1.5 0.3 6.5 10.4 2.0 1.9 3.4 2.6 3.2 0.5 7.6 5.0 3.3 3.2 1.1 1.7 3.0 3.8 6.4 1.7 3.6 2.0 0.4 10.5 2.2 2.2 12.9 8.5 3.7 7.8 1.0 0.9 8.8 4.9 3.0 1.2 2.0 0.4 1.2 0.6 1.1 1.6 3.8 1.8 0.5 0.8 1.8 6.5 2.8 2.9 4.0 1.9 2.3 2.1 3.7 1.2 2.2 0.7 4.3 5.7 4.5 2.1 1.3 3.2 1.4 0.2 4.3 0.6 0.8 0.6 0.1 3.2 0.9 0.8 0.6 16.3 0.4 1.9 0.5 0.0 1.2 5.3 7.7 1.3 5.9 6.1 2.3 9.7 1.0 6.6 8.5 ALPK2 HAK ENSG00000198796 "Alpha kinase 2" Q86TB3 18 58481247-58628957 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 35.3;skeletal muscle: 35.3;tongue: 12.4" "Cell line enhanced" "Detected in many" "BJ: 26.0;BJ hTERT+: 15.8;fHDF/TERT166: 23.5;U-138 MG: 13.3" "Cancer enriched" "Detected in some" 6 "renal cancer: 7.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "non-classical monocyte: 1.8" "Low lineage specificity" "Detected in single" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Low region specificity" "Detected in many" "HPA027377, HPA027976, HPA028084, HPA029801" Uncertain Approved Cytosol Cytosol "HPA027377: AB_10600635, HPA027976: AB_10611246, HPA028084: AB_10601996, HPA029801: AB_10602006" "unprognostic (7.35e-2)" "unprognostic (4.91e-2)" "unprognostic (1.64e-1)" "unprognostic (4.60e-3)" "unprognostic (2.64e-1)" "unprognostic (8.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (1.06e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "prognostic unfavourable (8.20e-5)" "unprognostic (5.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (3.20e-2)" 0.8 0.0 0.1 2.8 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.9 0.8 0.0 0.4 35.3 0.1 0.0 5.2 2.8 0.1 3.3 0.1 0.1 0.1 0.1 0.0 0.1 0.5 0.1 0.1 0.0 0.2 0.4 0.1 35.3 0.3 0.6 0.1 0.1 0.2 1.2 0.6 0.1 5.5 0.3 12.4 7.9 0.5 0.1 0.0 0.5 0.0 1.8 0.0 0.3 0.0 0.0 6.9 0.5 0.0 0.2 1.8 0.1 26.0 15.8 11.0 9.5 1.6 0.0 0.0 2.7 23.5 0.0 0.0 0.0 11.3 5.6 0.0 0.0 2.1 0.9 1.4 0.0 0.0 1.6 0.0 3.3 0.1 0.0 0.0 0.2 7.0 0.0 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.3 5.8 1.8 4.4 10.7 9.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.5 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 ALPK3 "KIAA1330, MAK, Midori" ENSG00000136383 "Alpha kinase 3" Q96L96 15 84816680-84873482 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.4;skeletal muscle: 47.6" "Cell line enhanced" "Detected in some" "BEWO: 9.2;HDLM-2: 6.9;HUVEC TERT2: 9.9;LHCN-M2: 13.6;NTERA-2: 8.3;RH-30: 24.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA026558 Uncertain Approved Nucleoplasm Nucleoplasm "HPA026558: AB_1844774" "unprognostic (2.69e-2)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" "unprognostic (4.61e-2)" "unprognostic (2.08e-1)" "unprognostic (6.53e-2)" "unprognostic (1.44e-3)" "unprognostic (1.42e-1)" "unprognostic (1.68e-2)" "unprognostic (1.82e-1)" "unprognostic (1.74e-3)" "unprognostic (1.23e-1)" "prognostic favourable (3.95e-7)" "unprognostic (1.76e-2)" "unprognostic (1.77e-1)" "unprognostic (2.96e-2)" "unprognostic (4.87e-2)" 3.7 1.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.5 1.4 0.0 0.1 1.7 0.8 0.2 0.3 18.4 0.0 0.6 1.6 1.3 1.0 0.0 0.1 0.0 2.1 8.8 6.9 0.6 0.4 0.0 0.4 0.2 47.6 0.0 0.2 0.8 0.0 0.0 1.2 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.1 0.1 0.1 0.2 0.0 9.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 6.9 1.1 1.1 0.2 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 9.9 0.0 0.0 13.6 0.5 0.0 0.1 8.3 0.0 0.0 24.4 0.1 0.0 2.5 0.0 0.1 0.0 1.3 0.0 0.0 6.0 0.2 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 ALPL "HOPS, TNSALP" ENSG00000162551 "Alkaline phosphatase, liver/bone/kidney" P05186 1 21509372-21578412 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 73.3;liver: 52.7;lung: 45.1" "Cell line enhanced" "Detected in some" "HSkMC: 52.2;hTEC/SVTERT24-B: 40.8;LHCN-M2: 29.7;SCLC-21H: 26.0" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 91 "neutrophil: 73.3" "Lineage enriched" "Detected in single" 127 "granulocytes: 73.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" 7300000 Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavourable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavourable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" 15.9 22.7 4.5 17.6 6.0 2.6 10.6 2.2 7.8 2.2 2.1 4.1 0.7 1.9 3.7 1.1 2.0 5.7 2.8 10.9 5.7 4.2 29.7 52.7 45.1 28.1 5.3 4.8 1.2 4.3 2.4 4.1 2.2 7.7 2.6 1.3 18.3 3.1 6.6 0.9 1.8 2.7 2.5 3.8 19.6 1.8 2.9 2.7 0.5 3.7 1.7 3.9 7.1 8.4 0.5 0.0 73.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 1.9 3.3 0.1 0.7 0.2 0.4 0.2 0.0 0.6 2.2 0.0 0.0 8.9 0.0 0.1 0.0 0.6 0.0 1.1 1.0 0.5 0.0 0.2 52.2 0.0 40.8 0.1 0.0 0.0 0.0 29.7 0.0 0.0 0.0 11.9 0.0 0.0 1.1 0.0 0.0 0.0 26.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 73.3 0.0 0.0 0.0 0.0 0.0 4.5 6.0 2.2 7.8 5.7 4.2 5.3 4.8 7.7 2.7 ALPP ENSG00000163283 "Alkaline phosphatase, placental" P05187 2 232378534-232382889 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "placenta: 240.2" "Group enriched" "Detected in some" 6 "HaCaT: 86.1;SiHa: 23.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "CAB026327, HPA038764, HPA038765, HPA051699" Enhanced Approved "Plasma membrane" "Intracellular and membrane" "Plasma membrane" "CAB026327: , HPA038764: , HPA038765: , HPA051699: " "unprognostic (4.86e-2)" "unprognostic (5.19e-3)" "unprognostic (6.67e-3)" "unprognostic (2.60e-1)" "unprognostic (2.44e-3)" "unprognostic (1.26e-2)" "prognostic unfavourable (4.33e-4)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 14.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 240.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.5 1.6 0.5 1.1 0.5 0.3 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 9.7 0.0 0.0 0.0 86.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 23.7 8.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.7 0.5 0.2 0.5 0.3 0.3 0.3 0.1 1.0 0.4 0.4 1.6 1.1 0.5 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALPPL2 ENSG00000163286 "Alkaline phosphatase, placental like 2" P10696 2 232406843-232410714 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.2;lung: 9.4" "Group enriched" "Detected in some" 4 "CAPAN-2: 24.5;HaCaT: 18.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 49.1;testis cancer: 64.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020698, HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" "Plasma membrane" "CAB020698: , HPA038764: , HPA038765: , HPA051699: " "unprognostic (1.39e-1)" "unprognostic (6.63e-3)" "unprognostic (1.27e-2)" "unprognostic (2.89e-1)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.69e-3)" "unprognostic (1.65e-1)" "unprognostic (2.67e-1)" "unprognostic (6.72e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.0 0.0 0.0 0.2 1.5 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.6 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.5 24.5 0.0 0.0 0.0 18.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986178-34008108 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease mutation, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.0;liver: 63.6" "Cell line enhanced" "Detected in many" "U-266/70: 58.5;U-266/84: 30.5" "Cancer enhanced" "Detected in all" "prostate cancer: 34.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" 65000 "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favourable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" 2.8 8.3 5.2 2.7 8.2 0.9 2.8 4.7 7.8 4.4 14.1 4.3 6.5 6.2 4.0 3.6 8.2 2.3 11.0 3.5 4.5 6.8 68.0 63.6 3.3 2.0 4.5 4.5 2.9 5.1 5.4 4.3 3.2 7.0 13.9 15.5 5.5 25.4 5.4 6.0 2.6 7.4 3.7 3.8 2.9 15.9 2.1 2.1 3.8 3.3 3.4 3.3 5.7 4.5 7.8 10.2 11.2 14.2 9.9 10.0 6.8 4.0 6.5 3.7 4.7 2.6 4.0 6.3 5.4 4.0 2.5 1.9 21.1 4.9 1.3 2.9 7.6 1.9 0.9 3.9 2.6 4.0 3.4 3.1 4.7 6.1 1.8 1.9 1.0 6.1 1.9 3.2 1.2 2.8 1.1 4.8 7.3 2.9 1.5 2.4 3.3 10.6 1.9 6.1 2.0 11.1 20.3 2.0 2.8 8.9 6.4 5.4 4.9 1.9 5.0 8.3 1.8 2.0 4.3 58.5 30.5 2.3 2.3 3.9 6.1 0.3 7.1 10.2 10.0 8.8 8.4 7.8 8.7 7.8 10.2 7.0 8.1 6.1 11.2 9.9 14.2 5.3 8.9 6.8 5.2 8.2 4.7 7.8 4.5 6.8 4.5 4.5 7.0 2.1 AMD1 SAMDC ENSG00000123505 "Adenosylmethionine decarboxylase 1" P17707 6 110874770-110895713 "Enzymes, Predicted intracellular proteins" "Polyamine biosynthesis, Spermidine biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 104.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029281, HPA029282" Approved Approved Nucleoplasm Nucleoplasm "HPA029281: AB_10600101, HPA029282: AB_10599965" "prognostic unfavourable (3.87e-4)" "unprognostic (4.68e-2)" "unprognostic (1.85e-3)" "unprognostic (1.01e-1)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "prognostic unfavourable (1.91e-6)" "unprognostic (1.18e-1)" "unprognostic (2.03e-2)" "unprognostic (6.50e-2)" "unprognostic (2.25e-1)" "unprognostic (4.20e-1)" "prognostic favourable (4.28e-4)" "unprognostic (8.62e-3)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (7.71e-2)" 16.7 15.2 29.7 16.9 35.6 38.1 17.8 27.3 34.2 18.6 18.6 45.7 12.5 14.9 18.9 14.2 28.9 14.7 17.5 18.5 32.5 21.5 25.2 16.9 16.9 18.5 39.0 22.0 16.9 20.2 21.8 26.2 33.8 32.7 104.7 19.4 12.8 17.5 19.2 15.3 14.5 13.5 18.4 38.3 16.7 18.4 15.8 46.0 19.4 25.5 20.1 24.6 12.6 16.8 6.6 12.9 42.0 14.0 6.1 9.2 6.5 20.6 14.1 17.3 32.7 26.2 16.6 22.6 29.7 32.9 23.2 27.4 22.4 13.0 36.4 14.4 18.8 14.2 40.8 26.9 32.0 21.3 23.6 37.7 12.9 23.5 15.6 32.5 22.6 11.2 24.9 16.0 32.4 20.2 28.1 31.8 39.0 12.5 43.2 25.0 21.2 12.9 23.8 17.4 21.6 26.3 27.7 22.2 15.8 18.1 23.0 26.2 14.8 27.9 13.2 15.4 11.6 82.0 32.0 8.7 14.1 37.3 17.7 26.0 19.7 15.0 9.8 14.7 7.6 11.6 8.9 6.3 7.6 8.7 12.9 6.6 9.2 9.0 42.0 6.1 14.0 5.8 8.8 6.5 29.7 35.6 27.3 34.2 32.5 21.5 39.0 22.0 32.7 46.0 AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943293-95968716 "Enzymes, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 99.0" "Cell line enhanced" "Detected in many" "A-431: 19.1;HMC-1: 21.1;Karpas-707: 26.1;SiHa: 17.5;SK-BR-3: 19.6;U-266/70: 21.1;U-266/84: 24.7" "Cancer enriched" "Detected in many" 14 "liver cancer: 23.4" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" 410000 Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: AB_10672967, HPA040149: " "unprognostic (4.81e-2)" "unprognostic (2.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (1.80e-2)" "unprognostic (2.88e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (3.35e-3)" "unprognostic (1.17e-1)" "unprognostic (4.63e-3)" "unprognostic (3.98e-2)" "unprognostic (1.70e-1)" "unprognostic (4.08e-3)" "unprognostic (2.61e-1)" 1.1 5.7 0.5 2.4 0.8 2.0 0.9 0.5 1.3 0.7 0.7 0.6 0.4 1.9 0.9 0.5 0.8 0.5 0.7 1.1 0.6 0.5 4.4 99.0 1.3 1.4 0.5 0.4 0.7 1.1 0.0 1.2 0.6 1.0 0.7 0.0 0.8 1.3 0.7 11.3 2.2 1.9 0.6 0.6 2.9 1.9 6.2 0.5 0.7 0.6 0.7 0.7 0.8 0.9 1.5 1.2 3.7 3.8 5.7 1.6 1.4 19.1 4.2 0.3 2.8 0.1 0.0 4.3 0.6 0.2 0.3 0.6 1.9 2.5 1.7 1.9 0.0 3.6 0.1 0.0 0.1 6.6 0.7 1.8 2.9 3.7 0.0 2.5 21.1 0.0 0.1 0.3 0.0 0.1 1.3 26.1 0.0 2.9 1.6 4.7 2.0 1.0 3.5 0.1 2.1 0.0 1.8 2.2 3.1 17.5 19.6 2.2 2.0 3.6 0.0 2.7 9.5 3.4 2.4 21.1 24.7 2.6 1.9 5.1 3.1 0.3 1.6 3.7 1.2 1.4 1.1 1.5 0.6 1.6 1.2 1.0 1.0 1.1 1.2 5.7 3.8 0.6 0.3 1.4 0.5 0.8 0.5 0.6 0.6 0.5 0.5 0.4 1.0 0.5 AMDHD2 CGI-14 ENSG00000162066 "Amidohydrolase domain containing 2" Q9Y303 16 2520357-2531422 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA041184, HPA041321" Enhanced Approved Nucleoli,Cytosol 69000 "Nucleoli, Cytosol" "HPA041184: AB_10803998, HPA041321: AB_10795588" "unprognostic (1.20e-1)" "prognostic favourable (5.19e-4)" "unprognostic (7.86e-3)" "unprognostic (2.39e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.48e-2)" "unprognostic (2.14e-1)" "unprognostic (3.28e-1)" "unprognostic (1.66e-1)" "unprognostic (1.88e-2)" "unprognostic (8.68e-2)" "unprognostic (1.30e-1)" "unprognostic (8.37e-2)" "unprognostic (4.71e-2)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" 12.8 16.9 8.6 11.4 10.1 12.7 10.9 7.3 16.0 9.4 8.8 11.1 11.3 19.5 10.4 11.9 8.4 9.0 14.6 11.8 7.1 4.8 15.3 10.5 20.0 15.8 9.8 11.3 8.1 10.1 6.5 7.5 10.7 8.9 8.6 2.4 10.9 16.1 9.6 10.2 15.0 19.1 7.2 8.3 22.2 11.5 25.7 7.9 7.3 9.9 11.0 8.9 9.3 8.0 9.8 17.1 16.6 15.8 4.9 8.1 4.8 6.4 8.8 1.9 4.0 2.1 1.7 14.3 5.9 2.5 4.7 5.9 6.3 11.6 3.0 4.2 1.1 5.9 1.1 1.6 0.1 3.8 5.3 4.3 7.9 8.2 8.0 3.1 14.1 4.0 1.7 3.4 0.5 2.9 9.8 7.2 1.9 15.6 5.0 8.6 4.1 6.8 19.7 3.0 11.0 1.3 3.6 7.3 7.2 3.8 9.2 15.5 9.5 0.8 4.0 5.3 8.1 10.5 3.0 15.2 9.7 5.9 5.9 5.9 6.6 9.9 6.1 16.5 7.4 15.8 5.5 9.8 5.9 5.3 2.3 7.4 5.0 4.2 16.6 4.9 15.2 17.1 8.1 4.8 8.6 10.1 7.3 16.0 7.1 4.8 9.8 11.3 8.9 7.9 AMFR "gp78, RNF45" ENSG00000159461 "Autocrine motility factor receptor" Q9UKV5 16 56361452-56425538 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026381, HPA029018, HPA077835" Approved Supported "Endoplasmic reticulum,Golgi apparatus" "Endoplasmic reticulum, Golgi apparatus" "CAB026381: , HPA029018: , HPA077835: " "unprognostic (1.72e-2)" "unprognostic (1.62e-1)" "unprognostic (1.62e-2)" "unprognostic (2.43e-2)" "unprognostic (3.60e-3)" "unprognostic (6.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-3)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (4.16e-2)" "unprognostic (5.52e-3)" "unprognostic (1.45e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (2.28e-1)" 13.9 25.9 21.3 10.6 23.8 14.1 28.7 12.6 25.0 17.2 21.0 24.5 18.5 21.6 16.6 25.2 20.8 15.3 13.7 17.6 20.6 20.2 35.2 50.0 13.3 19.3 22.3 14.3 20.5 14.0 33.3 13.0 41.6 18.9 14.9 11.8 23.8 12.6 18.6 71.6 11.9 18.8 16.0 25.0 14.3 12.2 36.8 17.5 14.6 18.6 10.1 19.3 15.5 16.9 18.3 10.6 21.4 13.1 11.7 9.7 4.0 17.4 24.4 10.7 19.6 33.4 18.8 9.4 18.9 23.4 25.7 20.2 21.6 16.6 45.6 21.9 25.5 16.4 16.3 14.7 24.6 10.2 16.8 13.8 10.1 23.2 29.3 10.7 16.0 21.8 21.3 20.5 24.6 14.9 14.3 6.3 18.6 11.1 16.0 11.4 5.0 16.8 18.1 21.5 17.1 15.9 18.3 10.7 8.2 44.4 15.6 14.3 46.9 11.2 19.3 24.3 13.3 12.3 12.7 13.6 11.9 24.2 17.6 7.8 11.1 21.4 8.5 10.9 6.9 9.9 9.7 18.3 8.7 7.1 7.8 15.6 9.1 9.5 10.5 11.7 13.1 10.6 9.0 4.0 21.3 23.8 12.6 25.0 20.6 20.2 22.3 14.3 18.9 17.5 AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 27.1;ovary: 38.2;testis: 15.2" "Group enriched" "Detected in some" 18 "HEL: 27.6;K-562: 15.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "hippocampal formation: 14.3" "HPA060228, HPA069636" Approved "Nucleoplasm,Vesicles,Centriolar satellite,Cytosol" Vesicles "Nucleoplasm, Centriolar satellite, Cytosol" "HPA060228: , HPA069636: " "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" 0.3 27.1 0.2 0.2 0.4 0.0 0.2 0.2 0.2 0.2 0.3 0.3 0.2 0.0 0.3 0.6 0.4 0.2 0.4 0.8 0.2 0.0 0.2 1.1 0.3 0.2 0.2 0.2 38.2 8.8 0.1 0.2 0.2 0.3 0.4 0.0 0.2 0.2 0.2 2.5 0.0 0.4 0.5 0.2 3.7 0.3 15.2 0.2 0.2 0.2 0.5 0.3 0.3 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 27.6 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.2 0.4 0.2 0.2 0.2 0.0 0.2 0.2 0.3 0.2 AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 212.4" "Cell line enriched" "Detected in single" 32 "U-266/70: 13.9" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 31 "memory B-cell: 3.0" "Lineage enriched" "Detected in single" 31 "B-cells: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA026478, HPA028080" Enhanced "Intracellular and membrane" "HPA026478: AB_10599969, HPA028080: AB_10600776" "unprognostic (1.98e-3)" "unprognostic (1.43e-3)" "unprognostic (8.75e-3)" "unprognostic (8.03e-2)" "unprognostic (1.95e-2)" "unprognostic (5.61e-3)" "unprognostic (8.21e-2)" "unprognostic (4.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.36e-5)" "unprognostic (1.68e-1)" "unprognostic (3.70e-1)" "unprognostic (3.36e-1)" "unprognostic (4.02e-1)" 2.9 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.2 3.3 0.0 0.0 3.5 0.1 3.3 1.4 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.6 1.2 0.0 2.1 1.5 212.4 0.1 1.4 0.0 0.1 0.5 0.7 0.1 0.0 0.0 0.2 25.3 2.8 0.2 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 AMPD2 SPG63 ENSG00000116337 "Adenosine monophosphate deaminase 2" Q01433 1 109616104-109632051 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 64.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.8;granulocytes: 29.7;monocytes: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027137, HPA045760, HPA050590" Approved Enhanced Cytosol 380000 Cytosol "HPA027137: , HPA045760: , HPA050590: " "unprognostic (2.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.50e-1)" "unprognostic (1.43e-3)" "unprognostic (9.01e-2)" "unprognostic (5.25e-2)" "unprognostic (3.91e-3)" "unprognostic (1.71e-1)" "unprognostic (4.02e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-3)" "unprognostic (1.50e-1)" "prognostic unfavourable (3.78e-10)" "unprognostic (9.16e-2)" "unprognostic (2.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" 8.1 22.7 20.2 21.7 41.3 64.4 4.9 16.3 26.8 9.5 10.1 9.5 6.3 17.1 9.0 6.0 5.9 11.8 13.2 5.2 21.7 19.4 7.8 13.0 8.2 10.7 14.2 14.2 16.3 9.4 13.0 37.1 10.8 18.3 9.7 5.7 15.7 9.1 12.2 2.1 10.0 11.6 9.1 8.5 15.9 8.3 5.3 12.2 10.3 6.4 3.0 7.5 8.2 8.1 2.8 8.8 29.7 24.5 3.0 4.3 5.4 10.9 12.8 18.8 15.8 16.4 16.4 7.1 15.6 32.0 16.0 15.8 9.7 4.7 5.4 12.0 29.3 8.6 9.8 14.5 9.9 8.8 13.3 28.6 16.8 10.8 15.4 12.1 30.8 18.3 7.7 21.2 16.5 13.8 8.8 14.8 11.4 17.0 17.9 29.0 12.1 13.6 12.8 7.2 8.4 14.7 6.7 14.6 15.3 10.7 13.0 12.7 7.3 11.3 13.2 19.8 23.0 24.2 16.1 29.6 14.3 7.8 29.5 18.9 20.6 0.5 9.2 11.2 3.4 19.6 4.3 2.8 3.3 3.4 8.8 1.7 3.8 2.8 29.7 3.0 24.5 1.4 2.6 5.4 20.2 41.3 16.3 26.8 21.7 19.4 14.2 14.2 18.3 12.2 AMPD3 ENSG00000133805 "Adenosine monophosphate deaminase 3" Q01432 11 10308313-10507579 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.2;skeletal muscle: 61.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.3;CAPAN-2: 19.0;HMC-1: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038662, HPA047408" Uncertain Enhanced "Nuclear membrane" "Nuclear membrane" "HPA038662: , HPA047408: " "unprognostic (2.24e-1)" "unprognostic (3.88e-3)" "unprognostic (1.44e-2)" "prognostic favourable (2.37e-4)" "unprognostic (1.89e-2)" "unprognostic (1.71e-3)" "unprognostic (2.91e-3)" "unprognostic (1.25e-1)" "unprognostic (7.83e-2)" "unprognostic (2.26e-1)" "unprognostic (1.84e-2)" "unprognostic (4.68e-1)" "unprognostic (3.06e-2)" "unprognostic (7.07e-2)" "unprognostic (4.42e-2)" "unprognostic (2.98e-1)" "unprognostic (2.12e-2)" 2.9 13.7 5.3 13.8 14.0 39.2 2.3 2.3 7.8 3.3 3.4 19.6 0.7 4.7 3.1 4.2 5.2 8.0 4.6 2.1 7.4 7.1 4.2 1.5 4.5 12.7 15.2 5.7 2.3 2.5 24.9 14.5 3.7 11.2 5.5 4.9 4.3 4.7 2.8 61.0 10.8 5.0 3.1 12.8 8.3 4.6 1.4 12.6 14.8 2.7 7.6 14.2 6.1 5.1 7.6 3.9 17.0 6.0 3.3 5.3 2.3 7.4 1.1 0.3 0.1 4.0 2.9 0.4 6.8 24.3 1.7 1.7 3.7 19.0 2.7 0.6 3.1 4.7 0.1 6.4 5.0 6.7 0.2 6.7 0.9 0.5 1.3 9.1 20.2 10.6 10.0 3.3 4.3 0.7 10.1 2.9 5.5 0.2 5.3 11.9 0.9 6.7 2.0 8.8 9.8 0.3 6.3 2.8 1.5 1.5 0.2 0.4 0.2 3.1 1.8 7.7 0.1 5.3 0.2 2.7 1.5 2.9 8.9 9.1 0.2 6.6 6.0 17.0 2.3 3.8 5.3 7.6 3.3 2.5 3.9 5.8 3.7 2.5 8.3 3.3 1.6 2.5 1.9 2.3 5.3 14.0 2.3 7.8 7.4 7.1 15.2 5.7 11.2 12.6 AMT "GCST, NKH" ENSG00000145020 Aminomethyltransferase P48728 3 49416775-49422753 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 10.2;Hep G2: 29.5;NTERA-2: 5.3;SH-SY5Y: 7.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 8.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005566 Supported Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA005566: AB_1844811" "unprognostic (2.10e-2)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (9.14e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (2.17e-3)" "unprognostic (1.94e-1)" "unprognostic (3.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.88e-1)" "prognostic favourable (3.90e-8)" "unprognostic (4.40e-1)" "unprognostic (1.91e-1)" "unprognostic (3.60e-1)" "unprognostic (1.98e-3)" 4.7 10.9 6.6 8.0 8.8 6.0 6.6 16.7 10.4 8.4 10.0 7.4 21.3 10.9 9.2 11.1 3.4 9.7 13.0 16.6 7.4 2.0 21.4 41.2 5.6 2.3 7.6 8.3 14.5 18.5 16.3 10.4 2.5 10.7 9.1 10.1 12.2 9.8 20.0 3.8 5.4 11.0 7.1 5.8 7.9 8.1 2.6 7.4 1.7 8.7 0.4 1.8 6.2 8.1 0.7 5.4 4.7 3.2 8.9 1.6 2.3 0.1 0.5 0.7 0.1 0.4 0.0 10.2 0.0 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.2 0.2 0.1 0.4 0.1 0.2 0.1 0.0 0.3 29.5 1.1 0.0 0.1 0.3 0.7 0.0 0.4 0.1 0.0 0.0 0.1 0.2 0.2 0.2 5.3 0.1 0.0 0.1 0.2 0.7 0.2 0.0 7.8 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 3.2 4.7 0.0 1.9 0.1 0.6 0.0 0.0 5.4 0.7 1.6 1.5 0.3 8.9 0.7 0.5 0.0 2.3 6.6 8.8 16.7 10.4 7.4 2.0 7.6 8.3 10.7 7.4 AMY1A AMY1 ENSG00000237763 "Amylase, alpha 1A (salivary)" P04745 1 103655290-103664554 "Enzymes, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 100 "salivary gland: 654.0" "Cell line enhanced" "Detected in some" "NTERA-2: 1.3;SH-SY5Y: 2.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "CAB004310, HPA045394, HPA045399, HPA046980" Enhanced "Secreted to digestive system" 68000000 "CAB004310: AB_626668, HPA045394: , HPA045399: , HPA046980: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 654.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.3 0.3 0.6 0.0 1.1 0.7 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.1 0.6 0.0 0.1 1.1 0.1 0.3 0.1 0.0 0.7 0.2 0.0 0.5 0.0 0.1 0.7 AMY1B AMY1 ENSG00000174876 "Amylase, alpha 1B (salivary)" P04745 1 103687415-103696680 "Enzymes, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "salivary gland: 302.4" "Cell line enhanced" "Detected in some" "NTERA-2: 1.2;SH-SY5Y: 2.1;U-266/70: 1.8" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" 68000000 "HPA045394: , HPA045399: , HPA046980: " "unprognostic (7.34e-2)" "unprognostic (2.59e-1)" "unprognostic (6.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.96e-1)" 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 6.5 0.2 0.2 0.2 0.0 0.2 0.2 0.2 4.0 0.2 0.2 0.2 0.0 0.2 0.2 0.7 0.2 0.2 0.2 0.2 23.0 0.0 0.2 0.2 0.2 0.2 0.0 0.2 302.4 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.2 1.1 0.2 0.2 0.2 0.2 0.1 0.3 0.3 0.6 0.0 1.1 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.4 1.2 0.0 0.7 0.1 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.6 0.0 0.1 1.1 0.1 0.3 0.1 0.0 0.7 0.2 0.0 0.5 0.0 0.1 0.7 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 AMY1C AMY1 ENSG00000187733 "Amylase, alpha 1C (salivary)" P04745 1 103750406-103758690 "Enzymes, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 34.3;salivary gland: 62.5" "Cell line enriched" "Detected in single" 4 "THP-1: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" 68000000 "HPA045394: , HPA045399: , HPA046980: " 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 62.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 9.6 4.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 AMY2A AMY2 ENSG00000243480 "Amylase, alpha 2A (pancreatic)" P04746 1 103616811-103625780 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "pancreas: 1849.4" "Cell line enhanced" "Detected in some" "THP-1: 1.0;U-2 OS: 1.2" "Cancer enriched" "Detected in single" 2010 "pancreatic cancer: 200.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045394, HPA045399, CAB045960, HPA046980" Enhanced "Secreted to digestive system" 77000000 "CAB045960: AB_2226891, HPA045394: , HPA045399: , HPA046980: " "unprognostic (3.27e-1)" "unprognostic (1.78e-3)" "unprognostic (3.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.13e-2)" 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.9 1849.4 0.0 0.2 0.2 0.2 0.2 0.0 0.2 59.9 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.3 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 AMY2B AMY2 ENSG00000240038 "Amylase, alpha 2B (pancreatic)" P19961 1 103553815-103579534 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pancreas: 939.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 11.3;EFO-21: 11.6" "Cancer enriched" "Detected in many" 15 "pancreatic cancer: 25.1" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "classical monocyte: 8.5" "Low lineage specificity" "Detected in many" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" 75000000 "HPA045394: , HPA045399: , HPA046980: " "unprognostic (8.69e-4)" "unprognostic (3.71e-3)" "unprognostic (6.41e-2)" "unprognostic (9.75e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-4)" "unprognostic (1.21e-2)" "unprognostic (1.63e-2)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (7.41e-3)" "unprognostic (1.55e-2)" "unprognostic (5.74e-2)" "unprognostic (4.22e-1)" "unprognostic (3.12e-4)" 1.7 0.5 0.8 0.8 1.5 0.4 1.0 2.6 0.8 0.9 0.9 0.8 0.8 0.5 0.8 1.0 0.8 1.5 0.9 1.1 0.8 0.5 1.5 1.1 1.0 1.1 1.0 0.9 1.2 939.9 0.8 1.1 0.8 0.8 0.9 0.4 0.9 145.7 1.0 1.7 1.3 0.9 0.8 0.8 1.0 0.4 0.8 0.8 0.8 2.4 1.1 0.8 0.8 0.8 1.8 2.6 1.9 8.5 0.1 1.1 1.9 0.0 0.6 1.2 0.0 6.3 11.3 1.2 0.9 0.9 0.7 1.7 0.0 0.2 1.1 11.6 0.3 1.3 0.1 1.4 1.6 1.4 1.7 2.0 4.3 0.8 0.9 2.6 2.8 7.7 7.5 0.8 1.3 0.2 0.0 3.4 0.9 0.0 2.0 0.5 0.1 1.6 0.6 0.0 5.0 6.5 2.1 3.1 0.5 2.6 1.2 0.8 0.1 1.5 0.9 0.4 1.0 0.5 0.7 3.9 0.1 0.3 2.1 1.9 0.2 0.0 8.5 1.7 0.8 3.9 0.6 1.7 0.3 0.4 2.6 1.8 1.1 0.4 1.9 0.1 3.6 0.8 0.3 1.9 0.8 1.5 2.6 0.8 0.8 0.5 1.0 0.9 0.8 0.8 AMZ1 KIAA1950 ENSG00000174945 "Archaelysin family metallopeptidase 1" Q400G9 7 2679522-2775500 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell line enhanced" "Detected in some" "BEWO: 6.1;MCF7: 6.3;SK-BR-3: 4.5;T-47d: 23.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 4.2;naive B-cell: 2.4;T-reg: 1.0" "Group enriched" "Detected in many" 6 "B-cells: 4.2;T-cells: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA020233 Uncertain "HPA020233: AB_1844818" "unprognostic (9.08e-3)" "unprognostic (1.66e-1)" "unprognostic (3.23e-3)" "unprognostic (1.81e-1)" "unprognostic (5.72e-2)" "unprognostic (7.79e-2)" "unprognostic (2.02e-2)" "unprognostic (3.42e-1)" "unprognostic (1.98e-1)" "unprognostic (7.16e-3)" "unprognostic (1.08e-1)" "unprognostic (1.21e-1)" "unprognostic (3.64e-9)" "unprognostic (1.60e-3)" "unprognostic (1.60e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" 0.7 0.7 8.4 1.2 7.1 2.0 0.9 1.4 10.0 3.2 0.6 6.5 0.0 0.8 4.0 0.6 0.7 1.4 1.0 0.9 5.9 4.9 0.5 1.2 2.8 1.2 6.0 4.8 1.4 0.8 0.7 1.1 3.6 4.2 0.8 0.7 0.2 0.6 0.6 0.6 0.8 0.6 3.3 3.8 2.0 0.7 1.4 4.4 0.0 0.7 0.0 1.8 0.7 0.7 4.2 0.1 0.4 0.1 0.1 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 6.1 1.9 2.9 1.4 1.9 0.0 0.8 0.5 0.2 1.8 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.4 0.0 6.3 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 4.5 0.0 23.9 0.0 0.0 0.1 0.1 0.1 0.0 0.9 0.2 0.0 0.5 0.0 0.1 0.4 0.0 0.2 0.1 0.0 0.0 4.2 0.1 0.0 0.0 2.4 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.1 8.4 7.1 1.4 8.7 5.9 4.9 6.0 4.8 4.2 4.4 AMZ2 ENSG00000196704 "Archaelysin family metallopeptidase 2" Q86W34 17 68247574-68257164 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023299, HPA052406" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "HPA023299: AB_2226909, HPA052406: " "unprognostic (3.04e-1)" "unprognostic (3.68e-2)" "unprognostic (3.93e-2)" "unprognostic (3.27e-3)" "unprognostic (3.32e-1)" "unprognostic (1.79e-2)" "prognostic unfavourable (1.32e-5)" "unprognostic (2.43e-1)" "unprognostic (3.92e-2)" "unprognostic (2.83e-3)" "unprognostic (3.59e-3)" "unprognostic (3.37e-1)" "prognostic unfavourable (3.14e-4)" "unprognostic (2.37e-1)" "unprognostic (2.95e-1)" "unprognostic (3.28e-1)" "unprognostic (7.62e-2)" 22.3 21.3 29.3 13.7 43.3 14.2 20.8 29.2 35.8 19.8 19.8 20.3 19.6 11.9 19.0 25.3 22.3 24.6 17.7 33.6 26.8 23.7 26.8 16.6 14.1 22.4 26.0 27.0 23.4 20.4 29.4 25.4 18.9 28.3 21.1 15.0 19.0 17.9 25.1 39.9 15.5 13.5 19.3 27.8 16.6 15.7 77.2 20.5 15.5 28.4 20.6 22.4 20.2 14.9 20.9 17.2 31.4 21.1 34.8 31.2 19.7 23.3 25.9 22.0 18.6 16.9 29.5 34.6 16.9 22.9 29.5 24.8 10.6 15.0 35.0 19.1 26.2 11.5 17.9 49.9 38.7 12.3 16.9 12.8 11.5 20.7 32.0 11.7 22.2 25.1 56.0 27.4 51.0 29.8 13.1 22.4 37.2 17.4 26.3 10.9 10.3 24.3 10.0 59.9 26.2 17.7 12.4 22.2 17.4 15.7 32.5 31.6 25.6 8.0 15.5 39.7 18.9 14.2 18.3 31.4 28.8 60.3 28.0 16.6 20.0 31.4 14.4 19.6 22.1 16.6 28.6 17.4 27.3 29.0 17.2 20.9 24.4 26.3 25.2 34.8 21.1 15.7 31.2 19.7 29.3 43.3 29.2 35.8 26.8 23.7 26.0 27.0 28.3 20.5 ANKIB1 "DKFZP434A0225, KIAA1386" ENSG00000001629 "Ankyrin repeat and IBR domain containing 1" Q9P2G1 7 92246234-92401384 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019358, HPA021780" Uncertain Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA019358: AB_1844831, HPA021780: " "unprognostic (1.77e-1)" "unprognostic (5.96e-3)" "unprognostic (1.23e-1)" "unprognostic (4.97e-3)" "unprognostic (2.75e-1)" "unprognostic (7.67e-2)" "unprognostic (4.88e-3)" "unprognostic (2.14e-1)" "unprognostic (4.24e-2)" "unprognostic (1.87e-2)" "unprognostic (1.52e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-3)" "unprognostic (4.05e-2)" "unprognostic (3.00e-1)" "unprognostic (3.00e-2)" "unprognostic (3.20e-1)" 11.9 11.8 21.4 9.2 29.2 5.8 12.3 15.0 25.5 13.6 12.1 34.9 16.0 10.7 12.6 16.4 11.8 10.0 14.7 9.7 22.7 20.0 25.3 10.1 10.6 11.5 31.1 18.4 13.1 12.7 28.5 10.9 12.2 23.4 10.2 12.6 8.4 12.7 18.4 8.6 14.0 11.3 13.4 23.8 11.4 10.9 19.4 35.0 11.5 17.1 4.5 11.1 13.1 13.3 4.8 4.5 3.1 2.0 3.2 4.9 1.1 17.3 10.6 9.4 14.2 17.4 18.6 10.0 13.6 15.6 13.2 17.4 7.7 26.8 10.0 12.0 20.1 8.4 8.6 14.3 20.2 16.9 7.1 6.3 12.2 6.2 11.9 9.0 14.0 12.6 12.1 15.6 20.6 14.9 8.0 21.6 15.6 14.0 19.1 8.4 10.2 12.0 7.2 11.5 10.7 14.0 15.0 13.0 15.4 19.4 21.9 11.5 9.1 5.1 13.3 25.6 20.7 28.8 13.8 13.6 24.2 12.6 14.8 10.9 29.2 2.8 1.3 3.1 2.7 2.0 2.2 3.9 2.6 3.8 1.1 4.8 2.2 2.8 0.8 3.2 1.6 4.5 4.9 1.1 21.4 29.2 15.0 25.5 22.7 20.0 31.1 18.4 23.4 35.0 ANKK1 X-kinase ENSG00000170209 "Ankyrin repeat and kinase domain containing 1" Q8NFD2 11 113387791-113400418 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.7;tongue: 6.3" "Cell line enhanced" "Detected in some" "HaCaT: 2.0;hTCEpi: 6.5;RT4: 3.1;U-266/70: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "basophil: 1.4;naive B-cell: 1.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA012813 Uncertain "HPA012813: AB_1844832" "unprognostic (5.63e-3)" "unprognostic (6.67e-3)" "unprognostic (5.09e-3)" "unprognostic (6.27e-3)" "unprognostic (5.56e-4)" "unprognostic (7.02e-2)" "unprognostic (2.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.50e-1)" "unprognostic (3.15e-1)" "unprognostic (3.36e-2)" "unprognostic (2.18e-1)" "unprognostic (5.39e-6)" "unprognostic (3.17e-2)" "unprognostic (3.83e-2)" "unprognostic (2.79e-1)" "unprognostic (4.65e-2)" 0.6 0.5 0.6 0.6 2.0 0.4 1.2 0.6 1.4 1.5 0.6 0.6 0.6 0.4 0.7 0.9 0.6 3.3 0.6 0.6 0.6 1.2 0.6 0.6 0.6 1.1 0.6 0.6 1.0 0.6 0.4 4.7 0.6 0.6 1.9 0.1 0.6 1.8 1.0 0.7 9.7 0.6 0.6 2.3 0.9 0.2 1.0 0.6 0.6 1.2 6.3 1.5 0.6 1.2 1.3 0.2 1.4 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.5 0.0 0.4 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.1 0.1 0.3 3.1 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.0 1.3 0.6 0.0 0.0 0.1 0.0 1.4 0.1 0.2 0.4 0.1 0.1 0.0 0.1 0.0 0.0 1.3 0.2 0.1 0.7 0.1 0.0 0.2 0.0 0.1 0.6 2.0 0.6 1.4 0.6 1.2 0.6 0.6 0.6 0.6 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784889-89815401 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 195.3;kidney: 78.7;pancreas: 93.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 77.0;BJ: 76.7;BJ hTERT+: 109.7;HMC-1: 69.8;HSkMC: 67.4;HUVEC TERT2: 85.8;TIME: 85.8;U-2197: 93.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in many" 5 "neutrophil: 59.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 59.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" 1500000000 "Plasma membrane" "CAB002417: AB_563491, HPA004625: " "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 21.3 1.1 0.6 2.9 0.8 9.5 17.0 1.0 1.3 8.2 21.2 0.8 0.5 195.3 1.4 8.4 3.6 1.4 27.7 3.7 0.4 0.3 78.7 37.7 9.7 9.3 0.9 0.9 1.8 93.9 0.0 0.7 14.7 1.3 8.6 4.7 4.0 6.6 1.8 1.6 4.9 155.8 4.3 1.2 7.2 0.8 4.7 0.2 5.6 1.5 4.2 3.8 4.7 3.0 0.0 6.9 59.4 12.8 0.0 0.0 5.5 0.0 4.9 0.0 0.0 60.1 77.0 0.5 76.7 109.7 9.4 8.3 0.5 0.0 0.0 0.9 65.8 0.0 0.5 0.0 3.7 0.0 0.0 14.5 0.4 11.4 35.4 1.0 69.8 67.4 0.1 29.7 0.0 85.8 0.4 0.1 3.6 0.0 0.0 34.1 0.2 5.2 0.0 0.0 0.8 42.9 0.0 0.1 0.7 0.0 0.1 0.0 0.0 6.7 85.8 41.4 0.0 93.5 0.0 0.0 0.0 0.0 0.1 0.0 2.2 5.7 12.8 10.4 0.0 7.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 59.4 0.0 12.0 0.1 0.0 5.5 0.6 0.8 1.0 1.3 0.4 0.3 0.9 0.9 1.3 0.2 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512949-36724549 "Enzymes, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 54.6;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 5 "NB-4: 20.9;THP-1: 16.0;U-937: 7.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 54.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021666, HPA026716" Approved "Secreted to blood" "HPA021666: , HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 8.4 3.4 5.2 17.2 4.9 19.3 2.8 1.9 3.6 3.1 5.3 7.4 0.2 4.9 3.9 7.2 2.5 3.1 8.4 3.4 4.8 3.8 3.1 6.8 9.4 23.2 6.9 2.0 2.1 2.3 0.6 2.4 5.7 5.8 3.8 7.3 3.8 4.5 1.4 1.5 1.6 7.6 4.7 12.6 57.4 3.3 1.4 6.8 14.0 2.9 0.4 10.9 7.2 2.8 0.3 34.8 18.7 54.6 19.2 8.8 31.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.9 0.0 0.3 0.1 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 20.9 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 7.0 0.0 0.3 54.6 17.6 8.8 47.9 1.8 0.3 0.4 6.1 34.8 0.0 1.0 7.8 18.7 19.2 20.2 0.5 0.1 31.0 5.2 4.9 1.9 3.6 4.8 3.8 6.9 2.0 5.8 6.8 AOC1 "ABP1, DAO" ENSG00000002726 "Amine oxidase, copper containing 1" P19801 7 150824627-150861504 "Enzymes, Predicted secreted proteins" "Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.6;placenta: 240.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 16.0;HaCaT: 4.9;NB-4: 4.8;RPMI-8226: 5.8;THP-1: 20.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 61.3;endometrial cancer: 39.1;pancreatic cancer: 26.9;renal cancer: 69.4;stomach cancer: 43.2" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "eosinophil: 20.3" "Lineage enriched" "Detected in many" 20 "granulocytes: 20.3" "Low region specificity" "Detected in all" "HPA031032, HPA031033" Approved "Secreted in other tissues" 800000 "HPA031032: AB_10670150, HPA031033: AB_10669670" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.84e-2)" "unprognostic (6.31e-3)" "unprognostic (8.31e-3)" "unprognostic (9.07e-3)" "unprognostic (6.42e-2)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (3.11e-1)" "prognostic favourable (1.71e-4)" "unprognostic (5.32e-3)" "unprognostic (3.62e-2)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" 0.3 0.3 0.3 6.7 0.3 0.0 0.3 0.3 0.3 0.9 68.3 0.2 1.2 30.2 0.3 3.9 1.7 0.3 4.4 0.3 0.3 0.3 37.9 1.5 0.3 0.6 0.3 0.1 0.3 0.6 0.0 0.3 240.4 0.1 1.3 15.5 0.1 0.4 0.2 0.3 0.8 108.6 0.2 0.3 0.4 2.7 1.8 0.1 0.7 0.3 0.1 1.0 0.4 0.4 0.0 1.0 20.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.1 0.0 0.0 0.0 2.5 16.0 0.0 2.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 4.8 0.2 0.0 0.0 0.0 5.8 0.2 0.1 1.8 2.1 0.0 0.7 0.0 0.6 20.9 0.5 0.2 0.1 0.4 0.0 0.2 0.1 0.1 0.1 0.8 0.0 0.1 0.1 20.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.1 0.1 0.1 AOC2 "DAO2, RAO" ENSG00000131480 "Amine oxidase, copper containing 2" O75106 17 42844600-42850707 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "retina: 133.5" "Cell line enhanced" "Detected in many" "ASC diff: 14.3" "Cancer enhanced" "Detected in some" "testis cancer: 3.8" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 4 "neutrophil: 4.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA057779 Uncertain "Intracellular and membrane" "HPA057779: " "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (5.10e-4)" "unprognostic (1.90e-2)" "unprognostic (1.48e-2)" "unprognostic (2.42e-1)" "unprognostic (4.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.39e-1)" "unprognostic (3.64e-2)" "unprognostic (2.16e-2)" "unprognostic (8.27e-3)" "unprognostic (4.55e-5)" "unprognostic (3.55e-2)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "prognostic favourable (2.47e-4)" 11.6 1.2 0.9 1.3 3.2 1.8 3.1 3.2 1.6 1.5 1.1 0.9 0.9 0.6 1.5 1.2 1.0 1.5 1.5 1.3 1.2 1.8 0.9 3.6 2.2 1.0 0.9 0.9 1.0 1.2 0.8 2.1 0.9 0.9 1.3 0.5 133.5 1.2 1.2 1.4 1.2 1.0 1.3 1.0 1.7 0.7 6.5 0.9 1.0 1.0 0.9 1.2 1.6 0.9 0.1 0.0 4.0 0.0 0.0 0.6 0.0 0.2 2.8 0.6 3.1 14.3 1.4 7.4 0.9 0.9 2.0 2.8 2.2 0.3 1.1 1.4 0.3 1.2 2.7 0.7 4.1 2.3 7.3 0.4 1.3 2.2 0.9 0.4 2.8 2.2 2.5 1.9 2.9 0.5 0.7 2.6 0.6 0.3 0.6 1.1 1.1 0.9 1.4 2.8 2.2 0.4 4.4 1.0 0.6 0.1 1.0 4.0 0.5 0.2 0.5 1.9 4.0 2.5 1.2 5.7 5.5 1.1 0.5 2.6 1.0 0.0 0.0 0.8 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.9 3.2 3.2 1.6 1.2 1.8 0.9 0.9 0.9 0.9 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase, copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 18 "ASC diff: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 13 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.2" "Low region specificity" "Detected in many" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" 240000000 Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavourable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavourable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavourable (6.98e-4)" 97.0 11.5 0.4 18.7 1.0 0.0 67.7 0.5 1.3 26.9 44.3 1.0 16.3 3.6 44.7 34.8 36.1 18.5 50.9 12.1 0.4 0.4 5.8 8.3 48.0 7.9 0.5 1.2 23.8 2.4 2.2 1.3 10.8 2.0 36.5 9.4 32.1 8.0 24.7 7.7 5.5 15.0 79.2 0.6 7.5 17.7 16.2 0.3 1.0 6.6 11.6 2.6 75.9 20.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 83.5 0.1 1.3 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.2 0.3 1.4 0.1 0.1 4.6 0.2 0.0 0.2 0.9 0.2 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.1 0.1 0.2 0.2 0.7 0.0 0.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.3 0.1 1.2 1.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.5 1.3 0.4 0.4 0.5 1.2 2.0 0.3 AOX1 "AO, AOH1" ENSG00000138356 "Aldehyde oxidase 1" Q06278 2 200585868-200677064 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 228.8" "Cell line enhanced" "Detected in many" "ASC diff: 83.9;ASC TERT1: 43.1;HSkMC: 17.3;hTERT-HME1: 17.3" "Cancer enriched" "Detected in many" 9 "liver cancer: 122.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040199, HPA040215" Enhanced 410000 "HPA040199: AB_10795273, HPA040215: AB_10795360" "unprognostic (4.39e-2)" "unprognostic (1.03e-3)" "unprognostic (1.96e-1)" "unprognostic (3.15e-2)" "unprognostic (1.17e-4)" "unprognostic (1.92e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (5.48e-2)" "unprognostic (2.00e-2)" "prognostic favourable (6.05e-5)" "unprognostic (1.33e-2)" "unprognostic (8.16e-3)" "unprognostic (3.38e-2)" "unprognostic (4.99e-3)" 12.8 55.6 0.1 1.8 0.4 0.2 10.5 0.3 0.2 2.9 3.2 1.3 18.6 0.3 2.0 11.1 3.9 8.1 4.0 3.5 0.3 0.0 20.8 228.8 3.6 7.5 0.2 0.2 12.2 28.5 0.2 0.8 1.9 0.6 4.4 1.0 1.6 2.7 20.1 2.5 3.2 1.7 6.9 0.4 1.7 2.4 10.8 0.2 0.1 4.8 2.7 0.6 7.1 10.6 0.0 0.0 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.0 83.9 43.1 0.0 1.3 2.5 1.1 2.1 0.0 0.0 0.0 0.1 1.7 0.0 0.0 3.8 4.7 0.0 0.1 0.0 1.0 4.2 5.6 0.1 0.0 17.3 1.0 5.5 17.3 0.0 0.0 0.0 3.8 0.1 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 6.6 2.9 2.3 0.0 0.5 0.0 0.0 0.5 2.3 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.3 0.2 0.3 0.0 0.2 0.2 0.6 0.2 APEH "D3F15S2, D3S48E, DNF15S2" ENSG00000164062 "Acylaminoacyl-peptide hydrolase" P13798 3 49674002-49683963 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029700, HPA029701, HPA029702, HPA029703" Enhanced Enhanced Cytosol 1600000 Cytosol "HPA029700: AB_10599278, HPA029701: AB_10600333, HPA029702: AB_10602411, HPA029703: AB_10601348" "unprognostic (4.93e-2)" "unprognostic (5.42e-2)" "unprognostic (6.04e-3)" "unprognostic (2.71e-1)" "unprognostic (9.32e-2)" "unprognostic (8.20e-2)" "unprognostic (3.65e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (8.03e-2)" "unprognostic (3.21e-1)" "unprognostic (4.30e-2)" "prognostic favourable (3.32e-10)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.34e-2)" "unprognostic (7.67e-2)" 12.3 31.4 14.3 16.9 18.4 17.3 13.5 14.2 28.2 13.4 23.5 14.4 25.3 24.2 14.1 19.0 23.8 17.2 19.1 23.1 14.2 14.2 33.6 36.9 15.0 23.9 13.9 20.0 13.9 22.7 33.5 26.6 18.6 16.3 16.1 26.6 19.5 19.8 19.8 55.1 16.9 21.7 14.1 9.8 19.2 21.9 22.3 11.7 22.6 26.6 26.6 20.7 19.9 13.7 20.5 26.2 30.4 27.9 21.8 29.5 28.1 25.4 20.8 22.8 29.6 19.9 13.4 30.2 16.6 21.4 23.4 25.1 33.4 27.6 32.6 18.7 18.9 23.6 25.4 38.5 17.8 15.5 10.5 35.1 34.7 27.3 19.8 37.6 54.7 15.2 29.2 13.4 27.8 21.1 21.7 16.2 23.2 23.5 26.5 19.1 13.5 19.0 10.1 19.6 42.3 46.3 60.4 10.9 18.9 18.8 45.7 20.7 30.1 20.1 9.6 14.5 25.4 22.6 22.4 18.6 13.2 19.4 25.0 26.6 20.8 30.2 25.5 30.4 28.5 27.9 22.5 20.5 23.5 26.7 26.2 17.4 24.9 24.2 8.0 21.8 26.7 21.0 29.5 28.1 14.3 18.4 14.2 28.2 14.2 14.2 13.9 20.0 16.3 11.7 APEX1 "APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1" ENSG00000100823 "Apurinic/apyrimidinic endodeoxyribonuclease 1" P27695 14 20455191-20457772 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding, Endonuclease, Exonuclease, Hydrolase, Lyase, Nuclease, Repressor, RNA-binding" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000956, HPA002564, CAB004294, CAB047307" Supported Supported Nucleoplasm 98000 Nucleoplasm "CAB004294: AB_626685, CAB047307: , HPA000956: , HPA002564: AB_1078174" "unprognostic (2.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.55e-2)" "unprognostic (4.74e-3)" "unprognostic (1.97e-2)" "unprognostic (5.88e-2)" "prognostic unfavourable (7.82e-5)" "unprognostic (4.21e-2)" "unprognostic (3.14e-2)" "unprognostic (2.46e-2)" "unprognostic (2.42e-2)" "unprognostic (1.68e-1)" "unprognostic (1.38e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-2)" "unprognostic (2.54e-1)" "unprognostic (7.08e-2)" 43.9 52.8 30.6 33.2 32.5 55.6 43.6 24.1 44.9 38.5 41.9 37.3 28.4 44.1 53.2 30.1 40.7 42.9 46.4 34.4 28.0 27.4 44.4 61.3 31.8 44.5 30.2 31.1 64.7 48.4 31.8 21.7 29.4 34.4 36.1 39.8 36.0 35.5 38.9 53.2 41.2 37.6 40.9 30.1 51.0 41.7 20.9 28.3 73.2 51.2 38.5 48.4 41.8 32.7 35.0 53.0 1.5 23.7 20.6 32.5 38.4 43.9 54.1 48.5 44.7 34.1 49.3 41.8 41.3 44.5 61.6 53.5 39.4 43.7 84.9 36.9 31.5 47.2 57.7 43.7 57.2 37.9 24.6 34.4 32.0 65.6 35.9 109.2 35.8 50.9 48.3 40.1 39.8 51.4 39.9 28.0 49.3 42.8 69.9 46.0 47.8 48.9 77.8 54.5 35.6 51.7 59.3 58.5 37.3 44.8 55.9 44.4 34.0 49.4 33.1 32.5 54.5 32.7 38.5 37.6 65.1 57.3 14.5 69.4 41.0 0.1 23.7 1.5 19.0 20.5 25.9 35.0 23.8 22.6 46.8 31.4 32.5 28.3 1.5 20.6 12.4 53.0 14.1 38.4 30.6 32.5 24.1 44.9 28.0 27.4 30.2 31.1 34.4 28.3 APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000357-55009057 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: " "unprognostic (2.90e-2)" "prognostic favourable (6.17e-4)" "unprognostic (4.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (5.62e-2)" "prognostic unfavourable (6.13e-7)" "unprognostic (5.89e-2)" "unprognostic (4.87e-2)" "prognostic favourable (5.21e-4)" "unprognostic (7.46e-2)" "unprognostic (3.16e-1)" "unprognostic (6.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "prognostic favourable (6.63e-4)" 11.1 12.8 8.6 12.0 12.3 11.9 10.2 8.7 11.8 10.0 12.3 13.7 8.2 12.3 11.5 12.6 20.8 10.7 13.9 10.6 8.7 7.2 15.4 18.5 10.3 14.2 9.7 6.0 14.4 10.7 10.7 12.7 17.8 8.8 11.0 15.1 9.1 10.4 10.0 10.3 16.7 18.7 10.0 9.9 18.0 10.8 7.7 8.9 21.9 10.6 10.2 27.4 11.6 12.7 6.7 9.4 9.2 9.9 26.6 7.5 6.3 22.0 19.8 7.9 11.4 11.5 7.7 13.4 9.1 12.3 17.6 17.3 10.8 18.6 14.6 14.3 8.5 16.6 18.0 17.3 13.4 11.8 13.7 17.7 19.8 10.9 7.4 10.9 16.8 7.6 14.2 24.9 9.0 14.0 9.1 9.9 13.1 21.5 14.7 14.3 15.6 24.0 13.1 13.1 15.9 9.5 11.1 7.3 8.0 17.2 20.9 8.8 16.4 8.5 8.1 10.5 15.2 21.1 11.8 10.3 13.3 12.1 11.2 18.7 12.4 9.2 7.8 8.5 7.5 9.9 6.2 6.1 7.1 7.4 9.4 6.7 6.4 6.2 2.9 26.6 8.3 5.1 7.5 6.3 8.6 12.3 8.7 11.8 8.7 7.2 9.7 6.0 8.8 8.9 APIP "APIP2, CGI-29, Mmrp19" ENSG00000149089 "APAF1 interacting protein" Q96GX9 11 34853094-34916499 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Apoptosis, Methionine biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021188, HPA024131" Approved Approved Nucleoplasm,Cytosol 77000 Nucleoplasm Cytosol "HPA021188: AB_10610977, HPA024131: AB_10602171" "unprognostic (2.80e-1)" "unprognostic (7.68e-2)" "unprognostic (5.30e-2)" "unprognostic (3.68e-3)" "unprognostic (4.22e-2)" "unprognostic (1.76e-1)" "prognostic unfavourable (1.99e-4)" "unprognostic (2.74e-2)" "unprognostic (3.84e-2)" "unprognostic (9.16e-2)" "unprognostic (2.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-1)" "unprognostic (3.23e-1)" "unprognostic (5.48e-2)" "unprognostic (7.44e-2)" "unprognostic (1.58e-2)" 23.2 29.8 12.0 13.7 18.7 9.6 15.8 7.6 12.6 12.7 13.8 17.9 16.8 10.5 15.3 10.8 12.2 13.9 12.1 15.4 14.5 11.7 24.8 21.8 16.2 14.4 21.5 11.7 13.2 19.7 13.4 10.3 12.5 21.1 14.1 12.6 10.4 18.5 20.4 48.7 6.8 13.9 16.0 27.8 13.9 19.1 9.7 21.1 23.9 19.0 12.9 11.5 19.0 16.1 14.2 25.6 14.9 19.8 17.5 15.8 10.6 8.5 9.1 10.9 2.5 8.9 8.8 4.9 12.6 12.2 12.4 14.2 5.4 7.5 26.2 7.7 4.6 10.2 19.8 8.5 16.1 16.1 18.8 13.5 9.7 13.7 13.7 37.4 10.4 8.6 6.3 7.9 13.0 10.2 31.7 16.1 8.6 8.2 17.9 17.3 8.6 21.7 11.5 31.8 8.9 12.8 12.3 9.2 4.4 15.8 12.7 15.5 13.3 11.6 8.5 9.4 9.4 24.0 3.0 15.8 11.9 29.5 11.7 8.0 11.9 4.7 16.9 14.9 11.0 17.5 13.6 14.2 13.4 11.9 25.6 13.4 13.8 11.7 4.1 17.5 19.8 16.5 15.8 10.6 12.0 18.7 7.6 12.6 14.5 11.7 21.5 11.7 21.1 21.1 APLF "C2orf13, MGC47799, Xip1, ZCCHH1" ENSG00000169621 "Aprataxin and PNKP like factor" Q8IW19 2 68467561-68655862 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 9.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029396, HPA034642, HPA034643" Uncertain Supported Nucleoplasm Nucleoplasm "HPA029396: AB_10610285, HPA034642: , HPA034643: AB_10602431" "unprognostic (9.37e-2)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (4.29e-3)" "unprognostic (5.18e-3)" "unprognostic (2.39e-3)" "unprognostic (3.24e-1)" "unprognostic (1.46e-1)" "unprognostic (4.00e-2)" "unprognostic (2.78e-1)" "unprognostic (1.25e-3)" "unprognostic (3.28e-1)" "unprognostic (5.02e-3)" "unprognostic (8.44e-2)" "unprognostic (5.95e-2)" "unprognostic (1.35e-2)" "unprognostic (1.85e-3)" 5.2 4.4 3.8 7.3 6.5 2.8 8.2 1.1 5.0 8.0 5.7 3.1 3.8 2.6 8.8 4.0 10.6 3.3 4.1 3.8 4.7 2.0 3.7 5.1 3.4 5.8 3.6 2.1 4.3 3.8 4.1 5.1 6.2 3.2 8.5 2.7 2.3 6.4 4.8 5.4 9.2 3.3 9.2 5.6 5.7 3.6 4.1 6.1 5.1 4.4 7.5 5.8 6.9 6.9 1.1 1.4 9.3 1.2 1.5 2.2 0.9 3.6 0.9 4.1 4.1 5.5 7.4 2.1 3.2 5.8 1.9 2.4 2.3 3.0 6.7 2.6 2.6 1.2 0.5 4.4 4.5 6.2 0.8 5.5 0.8 1.4 2.6 1.9 4.9 4.1 3.7 2.7 4.1 1.4 1.1 4.8 1.9 0.6 2.6 5.0 2.2 1.6 3.6 1.4 3.0 3.8 2.0 1.2 2.7 3.2 0.4 3.8 0.3 1.1 3.6 6.7 1.5 3.4 2.5 4.4 2.4 5.1 2.9 2.7 4.3 9.3 0.9 3.1 0.9 1.2 1.0 1.1 1.4 1.3 1.3 1.0 1.5 0.8 0.0 1.5 0.9 1.4 2.2 0.9 3.8 6.5 1.1 5.0 4.7 2.0 3.6 2.1 3.2 6.1 APOBEC2 "ARCD1, ARP1" ENSG00000124701 "Apolipoprotein B mRNA editing enzyme catalytic subunit 2" Q9Y235 6 41053304-41064511 "Enzymes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "heart muscle: 58.4;skeletal muscle: 163.0;tongue: 53.9" "Cell line enhanced" "Detected in some" "BEWO: 2.2;CACO-2: 8.9;HSkMC: 3.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 4.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014252, HPA017957" Enhanced "HPA014252: AB_1844932, HPA017957: AB_1844933" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-1)" "unprognostic (2.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (7.22e-2)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-1)" "unprognostic (2.01e-2)" "unprognostic (7.02e-2)" "unprognostic (3.69e-1)" "unprognostic (1.31e-3)" "unprognostic (2.19e-2)" 1.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 6.1 2.8 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.0 1.6 0.0 0.1 3.2 0.0 163.0 0.2 0.2 0.4 0.0 0.0 2.2 0.5 0.0 1.3 0.5 53.9 4.2 0.1 0.0 5.5 5.5 3.6 2.4 1.5 4.8 0.4 0.1 0.0 0.5 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 8.9 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.1 0.0 0.6 0.0 1.0 0.1 3.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.2 1.0 0.1 0.1 0.5 0.5 0.1 0.1 0.0 1.2 0.3 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.4 0.1 1.7 0.3 0.8 0.2 0.5 0.0 1.3 2.0 3.6 4.4 1.3 3.5 4.3 4.0 4.8 1.1 5.5 4.2 4.6 1.6 1.5 2.4 5.5 3.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APRT ENSG00000198931 "Adenine phosphoribosyltransferase" P07741 16 88809339-88811944 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026681 Approved Supported Nucleoplasm,Cytosol 1200000 "Nucleoplasm, Cytosol" "HPA026681: AB_1844964" "unprognostic (5.87e-2)" "unprognostic (5.10e-2)" "unprognostic (1.98e-1)" "unprognostic (3.67e-2)" "unprognostic (1.78e-1)" "unprognostic (2.50e-3)" "unprognostic (1.72e-3)" "unprognostic (6.90e-2)" "unprognostic (1.71e-1)" "unprognostic (1.82e-1)" "unprognostic (6.78e-2)" "unprognostic (8.74e-2)" "unprognostic (9.58e-3)" "unprognostic (1.14e-1)" "unprognostic (2.51e-1)" "unprognostic (4.75e-2)" "unprognostic (1.48e-2)" 22.9 37.1 10.9 33.6 13.2 32.9 31.6 10.1 15.3 22.7 31.1 10.7 33.6 27.1 19.9 28.3 50.7 21.0 30.4 22.5 9.1 8.2 27.7 60.4 30.6 94.2 14.8 10.7 17.9 58.2 19.4 15.6 19.3 11.0 25.1 15.1 13.9 48.2 37.4 26.2 49.8 24.3 18.4 12.1 30.4 27.5 16.0 12.2 37.9 29.5 49.7 35.8 18.5 32.8 65.4 92.1 24.2 70.2 58.2 83.7 104.7 25.4 37.4 7.3 33.0 9.0 17.9 39.1 19.3 17.2 22.8 8.9 38.5 30.9 23.7 37.8 10.9 27.3 12.0 31.7 4.6 16.7 71.6 20.2 17.7 40.2 28.6 13.8 16.5 19.1 34.3 18.1 23.0 28.4 42.4 17.8 11.5 93.8 39.0 40.8 28.2 49.0 42.0 11.4 56.1 25.1 17.3 36.5 22.4 36.8 21.5 20.8 71.0 27.5 18.3 20.6 18.0 16.6 18.9 35.0 29.3 65.2 30.3 36.8 18.1 8.5 70.2 24.2 63.0 57.7 83.7 63.2 81.9 67.5 71.6 65.4 75.9 64.3 4.3 58.2 37.1 92.1 66.1 104.7 10.9 13.2 10.1 15.3 9.1 8.2 14.8 10.7 11.0 12.2 APTX "AOA, AOA1, AXA1, EAOH, EOAHA, FLJ20157" ENSG00000137074 Aprataxin Q7Z2E3 9 32972606-33025168 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064930 Supported Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA064930: " "unprognostic (9.18e-2)" "unprognostic (2.65e-2)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (4.04e-1)" "unprognostic (8.16e-2)" "unprognostic (2.26e-2)" "unprognostic (1.00e-1)" "unprognostic (1.32e-2)" "unprognostic (2.78e-3)" "unprognostic (3.48e-3)" "unprognostic (3.49e-2)" "prognostic favourable (6.01e-5)" "unprognostic (7.87e-2)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (6.50e-2)" 12.9 20.3 17.5 11.2 18.4 19.9 16.5 15.1 21.7 12.0 15.2 19.3 9.3 11.7 14.7 12.9 19.1 14.7 8.0 11.9 13.3 13.9 17.9 23.4 12.6 11.8 16.4 16.5 11.8 14.3 15.8 14.3 12.1 20.2 12.1 18.1 14.6 12.5 11.9 14.1 20.6 13.8 14.6 15.7 11.7 12.5 18.2 14.5 8.8 10.5 12.6 16.1 13.4 12.1 17.1 18.4 16.1 20.8 26.4 19.4 15.0 21.2 16.1 12.3 10.6 12.5 11.0 16.2 14.2 14.8 17.4 19.2 21.4 7.5 16.6 8.6 11.9 11.3 20.0 19.1 21.6 22.4 8.2 9.8 23.1 21.8 14.6 15.8 9.4 14.7 23.4 19.9 25.9 16.6 14.8 16.5 16.2 9.1 14.2 23.2 18.7 17.3 12.8 8.5 11.8 14.3 12.9 8.5 7.2 13.0 11.7 9.5 13.3 6.5 10.2 9.7 12.9 16.7 14.6 7.2 11.8 16.6 14.4 12.9 7.7 9.1 17.7 14.9 13.4 16.3 17.6 17.0 15.2 15.5 18.4 17.1 18.0 14.6 16.1 26.4 20.8 17.9 19.4 15.0 17.5 18.4 15.1 21.7 13.3 13.9 16.4 16.5 20.2 14.5 AQR "fSAP164, IBP160, KIAA0560" ENSG00000021776 "Aquarius intron-binding spliceosomal factor" O60306 15 34851782-34969839 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040624, HPA055647" Enhanced Nucleoplasm Nucleoplasm "HPA040624: , HPA055647: " "unprognostic (1.73e-1)" "unprognostic (3.71e-2)" "unprognostic (2.97e-1)" "unprognostic (1.32e-2)" "unprognostic (1.03e-1)" "unprognostic (9.04e-2)" "unprognostic (4.25e-2)" "unprognostic (1.90e-1)" "unprognostic (5.95e-2)" "unprognostic (2.65e-1)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "prognostic favourable (4.83e-4)" "unprognostic (2.97e-1)" "unprognostic (2.47e-1)" "unprognostic (3.84e-1)" "unprognostic (3.13e-2)" 15.5 15.8 8.0 14.0 12.4 9.7 16.1 11.2 14.3 16.6 11.2 11.8 8.7 9.2 18.5 11.8 18.3 12.3 8.7 9.9 8.4 7.5 14.4 11.2 10.7 12.6 8.7 6.9 15.5 13.6 16.8 13.2 15.3 13.2 12.0 11.8 12.4 15.1 11.3 8.7 14.2 13.0 14.3 8.3 16.8 12.9 15.8 9.2 27.9 14.8 8.5 16.5 15.7 14.9 5.9 5.5 7.1 5.1 4.5 6.5 2.9 5.0 13.0 8.7 9.1 11.8 11.0 4.5 6.2 7.9 8.2 7.4 5.9 3.1 4.1 4.0 10.4 8.0 14.5 8.8 9.2 5.8 5.9 13.2 11.5 5.4 6.7 10.7 6.2 8.5 5.9 6.5 6.9 7.0 9.3 4.1 8.1 3.4 6.1 7.1 8.6 5.4 8.4 14.9 4.1 8.3 8.9 9.5 7.4 10.1 9.6 2.2 6.8 8.3 9.1 6.2 3.4 4.2 5.4 5.0 6.1 8.3 7.7 9.3 6.2 7.1 4.7 2.7 6.5 5.1 5.7 4.0 5.7 6.2 3.8 5.9 5.8 6.4 2.3 4.5 3.0 5.5 4.6 2.9 8.0 12.4 11.2 13.4 8.4 7.5 8.7 6.9 13.2 9.2 ARAF ARAF1 ENSG00000078061 "A-Raf proto-oncogene, serine/threonine kinase" P10398 X 47561100-47571920 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046188, HPA066326" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA046188: AB_2679578, HPA066326: AB_2685659" "unprognostic (1.21e-1)" "unprognostic (5.69e-3)" "unprognostic (2.47e-2)" "unprognostic (2.10e-2)" "unprognostic (7.63e-2)" "unprognostic (9.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.61e-1)" "unprognostic (6.75e-2)" "unprognostic (8.65e-2)" "prognostic favourable (1.45e-6)" "unprognostic (1.97e-1)" "unprognostic (2.01e-1)" "unprognostic (6.37e-2)" "unprognostic (4.71e-2)" 22.2 24.2 10.9 16.5 15.5 41.9 19.5 16.0 13.7 18.0 23.2 21.1 24.1 17.8 21.3 18.4 19.4 18.7 21.0 28.6 12.8 7.3 28.0 49.6 21.8 20.2 16.4 9.5 23.4 35.1 28.1 16.9 25.3 13.5 23.5 15.8 25.4 22.1 18.5 60.8 18.9 23.8 18.6 11.2 27.4 24.2 10.2 16.3 27.7 23.1 23.9 27.3 20.2 16.9 23.9 34.3 36.1 38.4 22.4 29.1 27.5 19.9 28.8 12.3 19.9 18.8 15.0 16.7 16.8 17.8 25.2 23.3 23.4 24.5 11.9 13.9 22.6 28.2 21.8 23.3 14.5 21.8 25.6 11.9 30.5 12.1 26.5 23.6 36.5 19.7 23.7 24.0 21.1 19.4 22.0 23.5 17.0 33.8 17.1 25.4 17.7 32.2 15.9 16.1 26.8 14.4 19.1 14.0 10.8 18.2 16.8 9.9 31.6 17.8 18.4 16.4 18.4 32.7 17.0 30.5 19.5 9.2 21.8 26.7 13.0 23.9 29.0 36.1 29.1 35.4 26.9 21.4 25.5 26.7 34.3 23.9 22.7 26.7 23.6 22.4 38.4 24.7 25.1 27.5 10.9 15.5 16.0 13.7 12.8 7.3 16.4 9.5 13.5 16.3 AREL1 "FIEL1, KIAA0317" ENSG00000119682 "Apoptosis resistant E3 ubiquitin protein ligase 1" O15033 14 74653437-74713115 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051306 Uncertain "HPA051306: " "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-1)" "unprognostic (1.92e-3)" "unprognostic (1.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.58e-3)" "unprognostic (9.32e-2)" "unprognostic (1.09e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (2.12e-1)" "prognostic favourable (4.67e-6)" "unprognostic (6.73e-2)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" "unprognostic (7.18e-2)" 8.5 13.7 11.8 12.2 22.2 17.6 8.8 14.4 25.7 9.3 11.9 16.5 9.8 13.8 12.8 11.4 14.5 12.6 8.4 12.3 11.3 9.7 17.5 9.8 12.1 12.0 8.6 8.4 11.9 15.7 19.4 9.5 11.9 13.3 10.0 15.0 18.3 14.9 9.8 17.9 10.7 16.0 10.1 11.1 12.3 12.0 20.0 7.2 17.1 18.6 11.2 14.9 11.2 10.8 3.2 7.0 9.7 7.6 4.6 7.3 4.5 12.1 15.3 15.2 15.4 13.3 9.6 13.1 13.0 15.3 16.6 16.0 12.8 14.8 10.4 7.0 18.5 15.8 17.5 14.1 21.8 18.6 8.6 16.0 10.2 8.0 8.7 11.3 15.9 12.3 10.3 12.0 13.0 15.6 12.3 11.7 21.3 15.2 11.9 4.9 10.2 15.9 12.7 17.6 6.5 12.7 27.9 16.6 21.8 11.9 15.9 8.4 13.8 12.0 21.8 16.2 19.1 9.6 15.9 14.1 20.7 21.4 19.2 8.6 12.2 2.1 4.8 9.7 7.3 7.6 5.4 3.2 4.2 6.0 7.0 2.1 4.6 3.8 9.7 4.6 4.1 2.3 3.8 4.5 11.8 22.2 14.4 25.7 11.3 9.7 8.6 8.4 13.3 7.2 ARG1 ENSG00000118520 "Arginase 1" P05089 6 131573144-131584332 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 284.1" "Cell line enhanced" "Detected in some" "Hep G2: 1.6;HL-60: 3.9;RH-30: 1.6;SiHa: 1.8;U-698: 2.2" "Cancer enriched" "Detected in some" 45 "liver cancer: 167.7" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "neutrophil: 24.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 24.4" "Region enhanced" "Detected in single" "cerebellum: 2.7" "Low region specificity" "Detected in single" "HPA003595, CAB009434, HPA024006, CAB056159" Enhanced 15000000 "CAB009434: AB_2058955, CAB056159: , HPA003595: AB_1078190, HPA024006: AB_1844987" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-1)" "unprognostic (9.95e-2)" "unprognostic (7.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (7.55e-3)" "unprognostic (8.35e-2)" "unprognostic (1.25e-2)" "unprognostic (2.90e-2)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (1.79e-2)" 1.0 0.0 0.1 0.1 0.1 34.3 0.6 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.3 0.1 3.0 0.2 0.0 0.1 284.1 5.1 0.8 0.2 0.1 0.4 0.2 0.0 0.1 1.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 14.6 0.1 0.1 0.1 3.5 0.0 0.3 0.1 0.5 0.3 1.7 0.3 0.3 0.7 0.1 0.1 24.4 0.4 0.0 4.7 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.1 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.2 1.6 0.0 3.9 1.3 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.5 0.1 0.3 0.1 0.0 0.0 1.6 0.4 0.0 0.3 0.2 0.1 1.8 0.4 0.2 0.1 0.5 0.0 0.0 0.2 0.3 0.1 1.0 0.1 2.2 0.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.1 24.4 0.0 0.4 0.1 4.7 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.1 ARG2 ENSG00000081181 "Arginase 2" P78540 14 67619798-67651720 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 53.7;thyroid gland: 75.4" "Cell line enhanced" "Detected in many" "HAP1: 25.0" "Cancer enhanced" "Detected in all" "prostate cancer: 49.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000663, CAB009435" Enhanced Supported Mitochondria Mitochondria "CAB009435: AB_2059089, HPA000663: AB_1078192" "unprognostic (8.74e-3)" "unprognostic (3.06e-2)" "unprognostic (1.35e-2)" "unprognostic (2.29e-1)" "unprognostic (2.30e-1)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-3)" "unprognostic (4.62e-3)" "unprognostic (5.37e-2)" "unprognostic (4.66e-3)" "unprognostic (1.72e-1)" "unprognostic (9.39e-2)" "unprognostic (4.26e-1)" "unprognostic (2.31e-1)" "unprognostic (4.34e-1)" "unprognostic (1.26e-1)" 1.5 3.9 2.4 1.7 6.4 0.6 2.7 8.3 5.3 9.3 5.4 0.5 2.0 2.1 3.7 2.3 7.3 0.8 4.9 2.1 3.3 5.5 41.4 2.0 1.7 0.6 3.2 1.7 8.8 2.6 32.1 22.5 4.4 4.6 53.7 1.1 3.4 26.6 3.8 17.2 0.8 10.4 2.2 3.9 0.7 1.4 1.9 2.1 0.1 75.4 13.6 2.2 5.3 4.1 2.5 1.7 2.0 1.4 0.3 2.9 3.4 3.5 0.5 6.2 4.0 0.9 0.0 8.4 2.8 7.5 9.1 15.4 15.3 1.8 6.0 0.7 1.8 0.8 25.0 11.3 11.0 0.2 6.2 2.7 1.1 17.5 2.7 0.6 16.4 0.4 14.8 4.4 21.6 15.3 7.9 0.0 0.6 1.7 0.9 0.6 11.8 0.2 0.2 0.8 6.9 7.4 6.0 13.8 5.2 1.7 1.7 2.6 6.4 0.2 3.1 2.7 6.9 0.2 2.0 0.5 0.9 2.0 5.5 3.1 4.6 0.3 1.4 2.0 1.1 0.5 0.5 0.7 0.3 0.9 1.7 2.5 0.6 0.6 1.7 0.3 1.2 0.1 2.9 3.4 2.4 6.4 8.3 5.3 3.3 5.5 3.2 1.7 4.6 2.1 ARIH1 "ARI, HARI, HHARI, UBCH7BP" ENSG00000166233 "Ariadne RBR E3 ubiquitin protein ligase 1" Q9Y4X5 15 72474326-72602985 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003295, HPA073245" Approved Approved "Nucleoplasm,Golgi apparatus" "Golgi apparatus" Nucleoplasm "HPA003295: AB_1845017, HPA073245: " "unprognostic (3.31e-2)" "unprognostic (1.92e-1)" "unprognostic (2.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.21e-2)" "unprognostic (5.45e-2)" "unprognostic (1.73e-1)" "unprognostic (9.43e-2)" "unprognostic (7.92e-2)" "unprognostic (1.37e-1)" "unprognostic (4.96e-2)" "unprognostic (9.19e-2)" "unprognostic (1.78e-1)" "unprognostic (2.93e-1)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (5.70e-2)" 15.3 15.6 11.4 17.4 15.5 24.6 13.3 20.4 21.5 15.8 14.5 10.4 14.0 17.0 21.1 11.2 14.2 12.3 14.4 19.7 10.5 10.5 10.9 10.5 13.7 9.3 10.1 15.0 17.3 13.5 12.9 14.0 15.4 12.6 14.0 7.6 13.0 13.2 13.1 68.3 16.3 13.5 15.8 10.7 11.4 12.5 55.2 10.0 16.9 11.7 13.0 12.7 18.4 20.4 1.9 1.1 4.6 1.5 2.1 2.5 0.3 9.3 9.9 9.7 5.7 5.0 3.6 11.5 10.6 3.8 4.8 3.3 10.0 8.1 9.2 15.9 4.5 13.5 10.0 5.5 2.7 16.3 6.9 6.9 12.2 6.6 3.6 10.3 8.1 4.2 1.9 5.3 6.9 3.5 7.2 11.0 4.7 6.1 10.0 4.0 10.5 3.6 11.4 11.9 5.2 2.7 15.8 9.1 10.4 13.8 6.2 16.2 5.0 11.9 9.1 7.9 11.1 30.6 14.7 11.5 23.2 10.7 5.2 9.5 8.4 4.6 1.0 2.2 1.7 1.5 1.5 0.7 1.3 1.1 0.7 1.9 1.6 1.5 3.4 2.1 0.7 1.1 2.5 0.3 11.4 15.5 20.4 14.0 10.5 10.5 10.1 15.0 12.6 10.0 ARIH2 TRIAD1 ENSG00000177479 "Ariadne RBR E3 ubiquitin protein ligase 2" O95376 3 48918821-48986382 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067381, HPA069715, HPA070963" Enhanced Nucleoplasm Nucleoplasm "HPA067381: , HPA069715: , HPA070963: " "unprognostic (7.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.26e-1)" "unprognostic (2.74e-1)" "unprognostic (2.55e-1)" "unprognostic (4.79e-3)" "prognostic unfavourable (1.70e-4)" "unprognostic (1.90e-2)" "unprognostic (4.01e-2)" "unprognostic (5.01e-2)" "prognostic favourable (7.31e-4)" "unprognostic (5.01e-3)" "prognostic favourable (6.60e-4)" "unprognostic (1.15e-1)" "unprognostic (7.04e-2)" "unprognostic (1.27e-2)" "unprognostic (1.39e-2)" 15.0 16.2 14.1 12.8 20.6 16.0 19.2 22.7 22.5 14.1 18.6 25.4 13.9 10.0 18.7 29.2 14.9 16.2 12.8 38.5 15.8 14.9 14.3 17.2 14.5 17.8 24.7 18.3 18.3 20.5 23.1 19.8 15.3 19.7 16.5 15.5 19.2 13.2 19.5 71.3 11.4 14.4 23.0 18.8 17.5 15.7 27.5 21.4 17.7 18.7 15.2 17.2 16.4 14.1 20.6 21.7 27.6 24.5 15.8 32.6 25.3 14.2 14.4 13.9 19.6 20.6 11.3 18.8 16.8 19.6 21.0 23.3 15.0 12.7 29.1 7.9 17.9 8.6 28.5 17.1 25.8 19.5 17.3 29.9 19.0 12.3 18.6 22.1 14.4 12.1 25.9 26.2 35.6 15.7 23.6 20.0 18.6 9.8 22.3 9.1 23.6 21.8 8.3 15.9 24.2 12.3 19.2 6.1 16.4 16.5 20.7 16.1 10.5 15.7 15.0 12.8 18.5 19.1 26.3 26.1 50.3 36.8 14.0 18.5 16.0 27.6 24.5 26.2 32.6 21.6 22.1 19.5 20.9 26.7 21.7 20.6 21.6 27.8 17.2 15.8 13.5 18.7 22.9 25.3 14.1 20.6 22.7 22.5 15.8 14.9 24.7 18.3 19.7 21.4 ARSA ENSG00000100299 "Arylsulfatase A" P15289 22 50622754-50628173 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005554, CAB025183" Enhanced Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" 4500000 "Golgi apparatus" Cytosol "CAB025183: , HPA005554: AB_1078220" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (4.07e-2)" "prognostic favourable (2.96e-5)" "unprognostic (4.66e-2)" "unprognostic (4.40e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-2)" "unprognostic (2.16e-1)" "unprognostic (4.47e-2)" "unprognostic (2.76e-1)" "unprognostic (9.90e-2)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (7.73e-3)" 19.0 15.2 14.0 15.2 15.7 16.6 15.2 11.9 17.9 12.0 20.3 21.4 26.4 30.2 13.3 21.4 15.6 18.5 23.3 18.8 13.4 8.8 17.5 24.1 15.7 16.8 19.1 10.3 9.3 45.4 13.1 20.4 18.5 17.3 15.8 8.8 14.0 36.8 21.9 6.3 11.1 23.4 8.7 13.2 25.6 23.6 27.2 17.9 10.6 18.7 7.5 16.5 14.8 13.3 5.6 15.7 30.1 19.8 3.9 8.9 7.7 4.0 5.7 2.8 5.3 20.5 11.2 6.9 6.6 8.0 2.9 4.9 1.6 6.3 2.7 4.0 10.7 6.3 0.6 6.0 0.4 1.2 4.3 1.6 6.4 5.7 14.2 2.4 16.8 13.3 11.8 4.7 3.0 6.4 1.7 38.4 5.8 4.6 2.1 2.7 0.8 5.6 1.9 0.2 12.6 4.8 6.3 1.3 4.2 9.3 8.3 4.7 3.7 3.0 11.3 2.0 7.8 7.4 1.9 9.1 0.8 2.1 5.9 2.1 6.7 4.3 13.7 17.1 8.9 16.0 7.9 5.6 6.5 7.3 11.2 5.6 3.9 5.3 30.1 3.9 19.8 15.7 8.5 7.7 14.0 15.7 11.9 17.9 13.4 8.8 19.1 10.3 17.3 17.9 ARSB ENSG00000113273 "Arylsulfatase B" P15848 5 78777209-78986087 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 17.2" "Group enriched" "Detected in many" 7 "dendritic cells: 5.5;granulocytes: 17.2;monocytes: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037770, HPA037771" Approved Approved "Golgi apparatus" "Intracellular and membrane" "Golgi apparatus" "HPA037770: AB_10671719, HPA037771: AB_10671720" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.97e-2)" "unprognostic (1.09e-2)" "unprognostic (7.34e-2)" "unprognostic (2.65e-1)" "unprognostic (8.69e-3)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (7.20e-2)" "unprognostic (1.74e-1)" "unprognostic (3.59e-2)" "unprognostic (2.48e-2)" "unprognostic (9.57e-3)" "unprognostic (9.88e-2)" "unprognostic (6.54e-3)" "prognostic unfavourable (3.42e-4)" 15.2 8.4 7.7 9.9 8.9 9.4 11.4 6.2 10.4 7.8 8.7 10.8 2.6 4.0 14.1 6.7 8.6 6.7 12.0 13.0 7.7 5.8 23.2 9.3 10.8 17.2 7.1 6.1 6.1 9.6 10.7 6.1 14.7 7.1 7.5 10.5 12.1 5.2 9.3 5.3 3.4 6.0 18.0 8.3 10.9 7.9 4.1 5.6 7.2 6.4 4.0 6.2 10.3 5.6 1.2 5.5 17.2 5.7 0.1 0.6 1.6 2.3 5.5 9.0 2.9 22.0 8.7 8.3 13.0 11.5 9.7 11.9 4.8 4.2 2.7 14.1 12.7 1.9 3.4 3.7 9.6 23.2 2.6 4.4 5.9 18.6 5.0 4.9 5.2 10.1 1.2 10.2 3.4 11.3 0.9 6.4 9.8 4.5 2.3 9.2 2.7 2.9 3.4 5.3 2.9 6.1 3.0 3.2 7.3 9.7 3.1 5.7 3.4 12.7 7.5 8.7 5.0 3.9 11.6 5.5 9.9 3.6 10.5 10.5 19.7 10.5 5.7 17.2 0.6 4.6 0.4 1.2 0.3 0.3 5.5 1.1 0.2 0.4 3.3 0.1 3.7 4.0 0.5 1.6 7.7 8.9 6.2 10.4 7.7 5.8 7.1 6.1 7.1 5.6 ART1 "ART2, CD296" ENSG00000129744 "ADP-ribosyltransferase 1" P52961 11 3645128-3664416 "CD markers, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 20 "skeletal muscle: 50.9;tongue: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051148 Uncertain "HPA051148: " "unprognostic (3.73e-1)" "unprognostic (4.58e-2)" "unprognostic (3.12e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-1)" "unprognostic (1.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" 1.5 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.2 0.1 50.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 13.7 0.5 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.2 0.4 0.0 ART3 ENSG00000156219 "ADP-ribosyltransferase 3" Q13508 4 76011184-76112802 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 29.1;heart muscle: 55.1;skeletal muscle: 85.2;testis: 42.6;tongue: 27.2" "Group enriched" "Detected in some" 8 "NB-4: 6.1;NTERA-2: 16.5;SK-MEL-30: 7.3" "Cancer enhanced" "Detected in some" "breast cancer: 2.3" "Region enhanced" "Detected in many" "cerebellum: 29.1" "Cell type enriched" "Detected in single" 5 "gdT-cell: 1.9" "Lineage enriched" "Detected in single" 18 "T-cells: 1.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 5 "cerebellum: 1.2" HPA011268 Enhanced "Intracellular and membrane" 45000000 "HPA011268: AB_1845059" "unprognostic (2.45e-1)" "unprognostic (2.84e-2)" "unprognostic (3.12e-2)" "unprognostic (2.77e-3)" "unprognostic (4.53e-2)" "unprognostic (1.34e-1)" "unprognostic (3.34e-1)" "unprognostic (9.85e-4)" "unprognostic (2.35e-1)" "unprognostic (5.10e-2)" "unprognostic (1.64e-2)" "unprognostic (2.95e-1)" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.48e-1)" "unprognostic (2.58e-2)" "unprognostic (6.61e-3)" 3.5 0.6 4.9 0.9 1.9 0.4 0.7 29.1 9.0 1.0 1.3 6.0 0.0 0.6 0.5 1.1 2.5 0.5 0.5 55.1 3.0 0.9 0.5 0.5 0.6 0.5 3.9 2.0 0.5 3.8 0.4 1.1 0.5 2.7 1.0 1.4 0.4 1.3 1.0 85.2 0.5 0.8 0.6 3.0 1.5 0.9 42.6 7.2 0.0 0.5 27.2 0.5 0.6 0.7 0.0 0.0 0.1 0.0 0.0 1.9 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 6.1 16.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 4.9 1.9 29.1 9.0 3.0 0.9 3.9 2.0 2.7 7.2 ART4 "CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (Dombrock blood group)" Q93070 12 14825569-14843533 "Blood group antigen proteins, CD markers, Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 33.7;lymphoid tissue: 17.8;placenta: 17.8" "Cell line enhanced" "Detected in some" "AN3-CA: 5.1;HEL: 10.0;Hep G2: 6.0;HUVEC TERT2: 22.9" "Cancer enhanced" "Detected in some" "liver cancer: 3.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in single" "olfactory region: 2.2" "Low region specificity" "Detected in many" HPA075664 Approved "Rods & Rings" "Secreted to blood" 11000000 "Rods & Rings" "HPA075664: " "unprognostic (2.50e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.62e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-3)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" 2.7 2.0 0.2 1.7 0.2 2.4 2.1 0.2 0.2 1.4 1.3 0.1 1.9 0.0 1.1 3.7 3.1 1.9 6.1 10.1 0.2 0.2 6.6 33.7 2.1 17.0 0.2 0.0 1.3 1.9 0.0 0.4 17.8 0.3 0.8 0.2 0.0 0.7 0.4 1.9 0.5 0.8 1.5 0.2 17.8 0.5 1.4 0.0 0.1 4.6 1.3 1.3 1.3 1.2 0.6 0.6 1.4 0.4 0.6 1.3 0.3 0.0 0.0 0.2 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 6.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.4 0.5 0.3 0.4 0.5 0.3 0.3 0.2 0.6 0.5 1.3 1.4 0.6 0.2 0.6 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.3 0.0 ART5 ENSG00000167311 "ADP-ribosyltransferase 5" Q96L15 11 3638503-3642316 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 12.1;testis: 33.3" "Cell line enhanced" "Detected in some" "AF22: 3.3;AN3-CA: 3.5;BEWO: 6.1;BJ hTERT+ SV40 Large T+ RasG12V: 3.5;HEK 293: 4.2;U-2 OS: 4.1" "Cancer enhanced" "Detected in some" "testis cancer: 4.5" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 11 "memory CD4 T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Region enriched" "Detected in single" 5 "olfactory region: 0.5" "Not detected" "Not detected" "HPA041637, HPA044099" Uncertain "Secreted in other tissues" "HPA041637: , HPA044099: " "unprognostic (6.32e-2)" "unprognostic (3.26e-5)" "unprognostic (4.09e-3)" "unprognostic (2.06e-4)" "unprognostic (1.53e-2)" "unprognostic (1.47e-2)" "unprognostic (2.22e-2)" "unprognostic (1.21e-2)" "unprognostic (5.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.17e-1)" "unprognostic (1.67e-1)" "prognostic favourable (1.85e-4)" "unprognostic (3.10e-3)" "unprognostic (3.46e-2)" "unprognostic (1.96e-1)" "unprognostic (3.18e-1)" 0.8 0.1 0.3 0.3 0.5 0.0 0.8 0.3 0.6 3.3 0.3 0.3 1.0 0.0 3.3 0.9 0.4 1.5 1.2 2.9 0.3 0.2 0.7 0.6 0.9 0.3 0.3 0.3 9.3 0.3 1.7 0.6 1.7 0.5 1.1 0.0 5.3 1.2 0.8 12.1 0.3 0.4 1.0 0.3 0.5 0.3 33.3 0.5 0.3 3.5 5.2 0.5 0.5 1.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 3.3 3.5 0.0 0.0 6.1 0.4 3.0 1.5 3.5 0.1 0.0 0.0 1.6 0.4 0.0 2.9 0.0 0.8 0.0 4.2 0.0 0.6 0.3 0.1 0.0 2.7 1.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.6 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 2.9 0.1 1.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.2 0.3 0.3 0.5 0.5 AS3MT CYT19 ENSG00000214435 "Arsenite methyltransferase" Q9HBK9 10 102869516-102901899 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 92.8;parathyroid gland: 30.0" "Cell line enhanced" "Detected in many" "AF22: 14.2;REH: 27.1;SH-SY5Y: 14.6;T-47d: 22.7" "Cancer enhanced" "Detected in single" "liver cancer: 1.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "NK-cell: 1.4" "Lineage enriched" "Detected in single" 6 "NK-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017856 Enhanced Approved Mitochondria Mitochondria "HPA017856: AB_1847420" "unprognostic (1.11e-1)" "unprognostic (2.02e-4)" "unprognostic (2.45e-1)" "unprognostic (2.25e-1)" "unprognostic (3.39e-1)" "unprognostic (1.66e-1)" "unprognostic (7.02e-4)" "unprognostic (3.22e-1)" "unprognostic (1.42e-1)" "unprognostic (3.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.83e-1)" "unprognostic (3.83e-10)" "unprognostic (1.04e-2)" "unprognostic (4.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" 2.0 92.8 3.7 0.7 8.6 0.5 2.6 4.5 6.4 4.0 2.0 2.2 0.4 1.3 3.8 3.2 2.1 2.1 5.2 10.0 5.7 3.1 7.4 22.4 1.7 0.9 2.8 4.4 3.9 8.7 30.0 2.4 0.5 4.6 4.2 0.8 8.9 2.2 3.4 6.0 1.8 1.3 3.9 2.7 5.6 1.7 3.5 1.6 0.3 3.2 1.0 0.7 1.8 1.8 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 3.9 14.2 8.9 0.3 0.3 2.6 4.1 3.5 6.2 7.6 10.6 0.6 0.2 1.2 5.3 0.2 12.1 0.7 6.4 0.0 3.5 0.0 1.7 10.4 4.1 0.2 0.1 1.9 1.6 0.8 0.0 0.2 0.0 0.2 5.5 0.1 2.4 0.3 6.8 0.6 27.1 0.0 0.1 1.3 0.1 0.4 14.6 0.0 0.2 1.9 22.7 0.3 0.1 1.3 0.0 2.0 0.0 0.3 0.2 0.0 4.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.7 8.6 4.5 6.4 5.7 3.1 2.8 4.4 4.6 1.6 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease mutation, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 71.3;SK-MEL-30: 101.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 27.0;classical monocyte: 53.6;eosinophil: 36.5;intermediate monocyte: 77.9;myeloid DC: 20.8;neutrophil: 73.8;non-classical monocyte: 80.5" "Group enriched" "Detected in all" 6 "dendritic cells: 20.8;granulocytes: 73.8;monocytes: 80.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" 410000 "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favourable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 41.9 16.8 18.5 11.2 20.7 20.7 44.2 17.6 19.1 23.9 18.5 15.4 31.5 11.9 17.6 30.6 19.8 16.2 22.3 120.4 17.5 19.2 45.0 13.2 57.2 40.2 27.0 16.7 13.0 16.5 18.0 28.2 36.5 29.8 19.5 19.7 33.3 20.4 39.4 18.2 16.4 16.4 19.5 40.9 25.9 12.9 8.2 15.9 4.5 73.4 15.1 12.3 31.4 16.0 9.8 20.8 73.8 80.5 6.7 6.0 38.7 8.2 11.5 4.5 11.2 71.3 8.4 7.0 8.4 12.0 4.2 7.4 6.1 11.5 5.1 10.8 9.3 10.9 2.8 4.4 5.1 3.9 6.6 22.8 8.7 16.4 19.5 4.6 25.6 18.1 15.3 6.0 4.1 1.1 4.0 10.9 11.9 8.3 2.5 8.3 5.3 7.1 3.3 4.6 6.9 19.7 47.2 7.4 9.9 7.8 25.9 101.4 8.4 5.3 7.3 5.4 7.8 9.9 4.0 13.4 30.3 3.7 16.0 10.5 4.3 27.0 53.6 36.5 6.0 77.9 5.4 9.8 4.5 4.5 20.8 7.7 5.3 4.8 73.8 6.7 80.5 3.9 4.9 38.7 18.5 20.7 17.6 19.1 17.5 19.2 27.0 16.7 29.8 15.9 ASAH2 ENSG00000188611 "N-acylsphingosine amidohydrolase 2" Q9NR71 10 50182778-50248610 "Enzymes, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "intestine: 43.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" HPA061171 Supported Approved "Focal adhesion sites" "Intracellular and membrane" 1200000 "Focal adhesion sites" "HPA061171: " "unprognostic (3.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.66e-1)" "unprognostic (3.84e-2)" "unprognostic (3.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (4.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.86e-2)" "unprognostic (5.64e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" 0.3 1.1 0.6 0.2 0.9 0.0 0.5 0.5 1.3 1.7 0.5 43.9 0.7 0.3 0.7 0.5 0.2 0.9 0.5 1.4 0.6 1.6 0.4 0.2 1.2 1.4 1.5 0.3 1.0 0.4 0.5 0.3 0.9 0.2 0.8 0.7 33.4 0.7 0.6 0.2 2.5 1.1 0.6 0.1 1.0 0.5 0.9 0.9 0.0 0.0 0.0 2.2 0.1 1.8 1.4 1.6 2.2 2.9 1.1 2.0 2.0 1.3 3.8 3.5 1.0 4.6 0.0 2.2 2.7 1.7 2.1 0.7 4.7 2.3 3.8 1.3 3.8 2.9 1.8 0.4 0.2 0.4 2.6 6.5 7.4 0.8 2.5 1.2 2.5 1.5 1.4 0.1 4.8 4.1 0.0 6.4 1.6 2.1 0.3 2.7 7.3 2.5 1.8 3.3 1.5 1.0 2.0 1.9 4.3 4.7 6.0 1.9 0.2 0.0 5.5 0.0 1.7 0.0 0.0 0.0 0.7 0.0 2.2 0.9 0.4 1.7 0.0 0.1 1.4 2.1 0.0 0.0 0.0 0.9 0.6 0.1 ASCC3 "ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH" ENSG00000112249 "Activating signal cointegrator 1 complex subunit 3" Q8N3C0 6 100508194-100881372 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031608, HPA031609, HPA031610" Enhanced Supported "Golgi apparatus,Cytosol" Cytosol "Golgi apparatus" "HPA031608: AB_10599970, HPA031609: AB_10600777, HPA031610: AB_10611526" "unprognostic (6.79e-2)" "unprognostic (1.46e-2)" "unprognostic (2.96e-3)" "unprognostic (1.12e-1)" "unprognostic (9.70e-3)" "unprognostic (4.56e-2)" "unprognostic (1.50e-1)" "unprognostic (5.14e-2)" "unprognostic (4.02e-1)" "unprognostic (3.34e-1)" "unprognostic (5.08e-3)" "unprognostic (1.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.90e-1)" "unprognostic (1.56e-1)" "unprognostic (1.01e-1)" "unprognostic (1.55e-2)" 15.9 15.4 10.9 15.5 14.5 13.6 13.4 16.1 11.7 16.7 13.2 7.7 10.1 11.4 16.4 12.9 18.4 11.3 11.1 14.9 9.7 8.4 10.4 28.3 12.6 13.1 13.1 7.6 13.8 15.1 25.0 38.6 26.1 10.4 16.4 17.1 6.4 15.4 14.0 13.6 15.3 16.1 12.2 15.5 17.7 11.5 11.7 12.4 25.0 10.6 11.6 15.2 16.0 17.9 8.5 9.4 5.9 6.4 6.0 7.8 1.8 7.0 8.8 13.3 8.2 14.9 19.0 20.7 31.0 20.0 10.7 12.4 18.0 5.7 21.7 6.1 20.8 15.9 11.4 27.5 17.4 13.7 9.8 16.4 16.5 11.7 13.7 17.4 12.7 17.2 14.1 15.6 19.9 19.6 19.4 9.9 29.5 6.8 8.6 5.3 7.0 6.7 10.5 10.1 8.0 10.6 20.0 8.7 6.6 12.9 11.7 5.3 6.5 9.9 26.9 12.0 9.1 10.3 13.0 4.3 3.9 19.4 8.6 13.2 12.5 5.9 3.9 2.4 6.7 6.4 7.8 5.8 5.6 6.0 4.1 8.5 6.5 6.2 0.3 6.0 5.2 9.4 4.3 1.8 10.9 14.5 16.1 11.7 9.7 8.4 13.1 7.6 10.4 12.4 ASH1L "ASH1, ASH1L1, huASH1, KMT2H" ENSG00000116539 "ASH1 like histone lysine methyltransferase" Q9NR48 1 155335268-155562807 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004806 Approved Supported "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA004806: AB_1845087" "unprognostic (2.98e-1)" "unprognostic (3.15e-2)" "unprognostic (1.10e-1)" "unprognostic (1.70e-2)" "unprognostic (2.05e-2)" "unprognostic (4.75e-2)" "unprognostic (1.42e-1)" "unprognostic (1.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.59e-1)" "unprognostic (1.07e-1)" "unprognostic (6.84e-2)" "prognostic favourable (3.80e-4)" "unprognostic (2.95e-1)" "unprognostic (1.62e-1)" "unprognostic (2.45e-2)" "unprognostic (1.94e-1)" 20.1 10.1 12.1 17.7 14.5 12.3 14.5 23.6 15.5 15.4 17.7 15.5 20.4 8.2 18.7 12.5 12.5 12.2 10.0 11.0 11.8 10.6 13.0 8.9 10.6 9.4 16.6 11.5 23.5 10.0 24.4 22.6 12.9 13.2 18.9 10.7 10.7 11.8 22.2 21.8 12.8 12.8 17.4 14.5 8.6 10.4 7.8 14.3 15.6 16.8 7.1 10.6 17.8 19.9 11.0 5.7 16.5 5.3 8.6 10.7 1.7 13.6 11.8 7.7 6.7 17.4 18.8 8.7 11.1 11.7 7.6 6.4 8.7 9.2 6.1 11.3 14.5 14.2 12.1 9.8 12.1 6.0 7.8 7.5 11.6 4.7 8.5 8.4 5.9 11.5 10.9 12.7 12.5 9.0 10.7 9.2 12.7 10.7 5.7 4.5 7.3 11.4 5.2 16.0 7.0 8.4 15.1 7.9 11.8 17.5 15.9 8.6 12.7 18.2 13.9 11.8 12.6 11.1 13.7 8.6 4.9 9.8 9.2 6.3 10.1 16.5 5.3 11.0 8.3 3.2 7.9 10.0 7.8 6.3 2.5 11.0 10.7 5.5 12.8 8.6 3.5 5.7 8.6 1.7 12.1 14.5 23.6 15.2 11.8 10.6 16.6 11.5 13.2 14.3 ASL ENSG00000126522 "Argininosuccinate lyase" P04424 7 66075798-66093558 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB003696, HPA016646" Enhanced Approved Cytosol 10000000 Cytosol "CAB003696: AB_425316, HPA016646: AB_1845096" "unprognostic (2.95e-2)" "prognostic unfavourable (4.05e-6)" "unprognostic (4.83e-1)" "unprognostic (4.18e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (2.07e-1)" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (7.25e-2)" "unprognostic (4.95e-2)" "unprognostic (2.07e-2)" "unprognostic (3.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (8.40e-3)" 5.6 4.8 4.0 8.0 4.3 7.3 5.9 7.2 7.4 5.5 17.2 3.7 7.8 20.8 5.0 7.1 7.7 4.9 19.5 4.3 3.7 4.3 16.0 99.5 8.1 4.5 4.4 6.2 5.9 10.4 3.3 5.8 3.3 7.2 5.4 12.4 5.8 7.1 5.7 2.4 4.1 16.6 3.4 3.2 8.6 12.6 2.1 3.5 1.2 7.1 7.9 5.9 5.2 5.9 8.6 19.3 20.7 18.4 30.4 9.2 10.7 18.2 7.5 4.1 14.8 9.4 7.3 9.0 12.8 11.2 18.3 16.7 16.8 22.6 5.6 20.5 16.8 5.0 2.6 21.7 5.3 4.6 3.4 7.4 7.3 26.1 17.7 8.4 21.7 13.7 7.9 12.8 20.5 18.0 13.1 10.7 10.1 13.0 1.7 11.6 6.2 9.7 4.5 4.3 19.2 13.3 11.0 7.1 9.7 11.7 40.8 4.4 17.8 7.6 20.4 23.2 12.0 9.2 16.5 11.7 6.1 7.3 21.9 16.0 18.7 12.1 18.1 20.7 7.7 18.4 6.5 8.6 5.2 6.1 19.3 5.6 3.7 4.0 4.0 30.4 13.8 1.2 9.2 10.7 4.0 4.3 7.2 7.4 3.7 4.3 4.4 6.2 7.2 3.5 ASNS ENSG00000070669 "Asparagine synthetase (glutamine-hydrolyzing)" P08243 7 97852118-97872542 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Asparagine biosynthesis" Ligase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 68.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 8.6;T-cells: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004924, HPA029318, HPA064737" Approved Enhanced Cytosol Cytosol "HPA004924: AB_2667295, HPA029318: AB_10602389, HPA064737: AB_2685341" "unprognostic (3.93e-2)" "unprognostic (2.51e-1)" "unprognostic (6.70e-2)" "prognostic unfavourable (4.24e-4)" "unprognostic (3.64e-1)" "prognostic unfavourable (8.79e-5)" "prognostic unfavourable (9.42e-6)" "unprognostic (2.28e-2)" "unprognostic (9.08e-2)" "unprognostic (1.89e-1)" "unprognostic (8.10e-3)" "unprognostic (2.53e-3)" "prognostic unfavourable (6.21e-7)" "unprognostic (5.33e-1)" "unprognostic (2.15e-1)" "unprognostic (6.21e-2)" "unprognostic (1.33e-1)" 6.5 7.5 15.9 10.9 21.4 7.6 9.9 31.7 32.3 5.7 10.1 9.4 5.6 6.5 10.0 19.9 10.2 6.9 6.8 9.2 24.5 20.4 6.5 5.9 9.6 16.0 16.3 13.4 19.2 68.0 16.7 16.7 3.2 35.9 9.2 12.7 4.4 49.9 9.3 3.5 13.6 7.8 11.3 20.6 11.0 20.8 16.9 9.2 3.6 16.7 8.2 15.0 9.6 6.6 8.6 1.4 1.5 1.2 2.2 13.2 3.2 18.8 7.2 7.3 59.3 5.8 8.2 17.9 13.9 8.9 6.7 19.9 9.3 7.6 14.8 7.0 28.3 8.6 18.9 22.0 15.9 18.5 14.0 4.7 3.6 6.9 53.7 30.2 13.3 16.1 74.0 8.7 53.8 5.4 26.5 52.6 10.4 39.9 0.8 8.0 10.0 19.7 2.3 1.3 38.8 4.3 3.7 31.9 24.0 3.6 19.3 75.0 8.2 21.2 1.4 3.3 21.8 8.7 6.5 62.4 31.1 56.4 41.2 13.8 31.7 1.5 0.3 0.5 3.8 1.2 4.9 8.6 7.4 3.4 1.4 6.2 10.2 5.5 1.5 2.2 0.8 0.1 13.2 3.2 15.9 21.4 31.7 32.3 24.5 20.4 16.3 13.4 35.9 9.2 ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503419 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.3;kidney: 33.2" "Cell line enhanced" "Detected in some" "ASC diff: 8.1;ASC TERT1: 6.3;CACO-2: 5.4;HSkMC: 11.4" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Uncertain Cytosol Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" 10.9 4.1 14.5 1.8 37.6 1.7 3.3 3.0 19.4 6.2 3.6 35.2 3.1 9.7 4.1 5.5 4.5 5.0 3.3 2.2 21.9 11.0 33.2 12.6 3.2 1.3 50.2 11.3 2.9 1.0 0.9 0.9 3.1 18.9 4.0 4.6 2.6 1.9 4.8 9.3 4.6 13.3 2.9 22.4 4.6 3.9 5.6 51.3 0.0 1.8 1.1 0.8 4.5 3.5 1.7 1.2 3.6 0.7 1.6 1.3 0.2 0.4 0.2 0.9 0.7 8.1 6.3 0.5 0.4 0.3 0.3 0.3 5.4 0.3 1.1 0.3 1.0 0.5 0.5 0.3 0.4 2.8 0.3 0.5 0.9 0.4 0.9 0.7 0.8 11.4 0.6 0.7 0.2 0.1 0.6 1.9 0.4 0.4 0.3 0.9 0.8 0.5 0.4 0.5 0.9 0.4 1.6 0.7 0.5 1.6 0.6 1.2 0.6 0.3 0.6 1.0 0.7 0.7 0.4 1.2 0.6 0.7 0.4 0.6 0.8 3.4 0.7 0.8 1.2 0.6 1.0 1.1 1.0 0.9 0.5 1.7 1.2 1.3 3.6 1.6 0.7 1.2 0.5 0.2 14.5 37.6 3.0 19.4 21.9 11.0 50.2 11.3 18.9 51.3 ASPDH ENSG00000204653 "Aspartate dehydrogenase domain containing" A6ND91 19 50511600-50514690 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 26.9;kidney: 24.7;liver: 59.8" "Cell line enhanced" "Detected in some" "HEK 293: 13.3;MOLT-4: 15.5;SH-SY5Y: 9.2" "Cancer enriched" "Detected in some" 13 "liver cancer: 24.2" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042631, HPA042654" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" 51000 Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA042631: AB_10794530, HPA042654: AB_10794383" "unprognostic (5.79e-2)" "unprognostic (9.47e-2)" "unprognostic (8.97e-3)" "unprognostic (6.13e-3)" "unprognostic (5.13e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-3)" "unprognostic (3.32e-2)" "unprognostic (2.87e-2)" "unprognostic (2.09e-2)" "unprognostic (2.87e-3)" "unprognostic (6.70e-3)" "unprognostic (9.65e-3)" "unprognostic (3.36e-2)" "unprognostic (1.07e-1)" "unprognostic (5.31e-4)" "unprognostic (1.99e-3)" 1.3 3.2 11.7 1.6 16.2 1.3 0.9 7.4 26.9 0.9 1.0 8.9 0.0 6.9 1.1 0.9 1.2 0.9 2.3 1.2 12.9 8.3 24.7 59.8 1.1 1.6 9.2 9.8 0.9 1.5 0.9 7.7 0.9 4.1 1.2 0.9 1.0 2.3 0.9 1.1 1.8 2.9 0.9 5.1 1.4 1.1 1.1 6.6 1.3 1.7 0.0 0.9 1.1 0.0 0.0 0.4 0.0 0.5 0.0 0.2 0.0 0.1 2.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 13.3 0.0 0.5 3.7 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 1.6 15.5 0.1 0.0 0.3 0.3 0.3 1.0 0.0 0.2 1.7 9.2 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.7 0.0 0.0 3.7 0.7 1.9 0.2 2.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 11.7 16.2 7.4 26.9 12.9 8.3 9.2 9.8 4.1 6.6 ASPG C14orf76 ENSG00000166183 Asparaginase Q86U10 14 104085679-104115581 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 29.7;liver: 88.7" "Cell line enhanced" "Detected in some" "EFO-21: 2.6;HDLM-2: 3.0;HeLa: 2.4;HMC-1: 3.1;RPTEC TERT1: 1.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA069761 Enhanced "HPA069761: " "unprognostic (1.45e-2)" "unprognostic (7.43e-3)" "unprognostic (2.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-2)" "unprognostic (1.74e-2)" "unprognostic (1.72e-2)" "unprognostic (3.47e-2)" "unprognostic (1.98e-1)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "unprognostic (1.10e-1)" "unprognostic (8.75e-2)" "unprognostic (7.98e-2)" "unprognostic (3.85e-1)" "unprognostic (1.52e-2)" "unprognostic (2.32e-2)" 0.7 0.5 0.4 0.4 0.5 0.0 2.1 0.4 0.5 1.5 2.3 0.5 0.4 0.5 1.6 1.0 10.2 2.0 0.8 29.7 0.4 0.0 9.8 88.7 1.3 0.9 0.4 0.4 4.9 0.4 0.7 0.4 0.8 0.7 0.4 0.8 1.2 0.8 0.4 0.4 5.2 0.8 1.1 0.4 0.4 1.6 0.9 0.4 0.4 1.3 0.6 1.7 0.5 2.8 0.2 0.0 1.0 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.2 1.8 0.8 2.6 0.0 0.2 0.0 0.0 0.0 3.0 0.0 0.0 2.4 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.7 0.0 0.7 0.6 1.8 1.9 1.4 1.2 0.0 0.1 0.8 0.2 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.5 0.4 0.0 0.4 0.4 0.7 0.4 ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 21.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" 900000 "Endoplasmic reticulum" "HPA055161: , HPA059303: " "unprognostic (8.07e-2)" "prognostic unfavourable (8.07e-5)" "unprognostic (1.73e-2)" "unprognostic (4.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-2)" "prognostic unfavourable (3.61e-4)" "unprognostic (6.39e-2)" "unprognostic (3.64e-1)" "prognostic unfavourable (1.75e-4)" "unprognostic (9.50e-2)" "prognostic unfavourable (1.57e-5)" "unprognostic (8.96e-2)" "unprognostic (1.65e-1)" "prognostic unfavourable (4.24e-4)" "unprognostic (2.74e-2)" 104.6 60.4 27.3 15.0 29.5 4.8 84.3 35.2 31.3 22.3 23.8 10.6 18.3 14.0 16.8 17.8 22.4 16.5 19.1 33.9 26.1 22.4 19.0 23.0 22.5 10.9 21.1 22.2 20.5 13.8 12.5 15.7 14.7 20.5 17.3 26.8 23.6 28.8 23.4 103.1 12.0 13.9 26.1 16.7 12.8 30.5 6.4 19.6 2.9 31.7 36.0 13.7 30.0 25.4 3.3 21.0 15.9 5.2 4.9 3.4 2.3 50.0 72.7 10.2 6.2 45.8 43.5 3.5 89.8 83.5 38.5 40.4 12.4 66.7 3.8 6.2 52.6 18.7 6.3 31.3 65.8 1.4 6.4 8.9 44.2 34.0 29.4 1.3 1.4 35.7 7.1 21.4 27.3 16.2 2.4 3.6 33.8 10.6 0.3 1.8 5.8 42.9 2.4 11.0 0.8 23.5 41.5 10.6 3.7 27.9 13.2 11.1 5.4 2.4 50.8 39.0 20.0 35.6 31.6 2.3 2.9 0.1 102.6 0.8 26.0 1.1 5.2 0.1 1.6 1.9 3.1 3.3 2.3 1.6 6.1 3.3 3.4 1.6 15.9 4.9 1.0 21.0 2.3 2.3 27.3 29.5 35.2 31.3 26.1 22.4 21.1 22.2 20.5 19.6 ASRGL1 "ALP, ALP1, FLJ22316" ENSG00000162174 "Asparaginase like 1" Q7L266 11 62337448-62393412 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 52.4;cervix, uterine: 68.7;testis: 57.6" "Cell line enhanced" "Detected in many" "EFO-21: 30.0;HAP1: 28.9;RPTEC TERT1: 25.6;SCLC-21H: 39.5" "Cancer enhanced" "Detected in all" "endometrial cancer: 53.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 51.4;eosinophil: 52.4" "Group enriched" "Detected in many" 4 "granulocytes: 52.4;monocytes: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029725, HPA055572, CAB070192" Enhanced Approved Nucleoplasm,Microtubules Microtubules Nucleoplasm "CAB070192: , HPA029725: AB_10602328, HPA055572: AB_2682854" "unprognostic (1.14e-1)" "unprognostic (8.38e-3)" "prognostic favourable (6.14e-4)" "prognostic favourable (1.56e-5)" "unprognostic (5.35e-2)" "unprognostic (8.19e-2)" "prognostic unfavourable (9.46e-4)" "unprognostic (8.67e-2)" "unprognostic (1.85e-1)" "unprognostic (3.54e-2)" "unprognostic (2.71e-1)" "unprognostic (4.44e-1)" "prognostic favourable (4.32e-7)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (5.43e-3)" "unprognostic (1.40e-1)" 3.6 2.6 27.8 3.8 37.0 7.1 4.6 12.3 22.3 68.7 7.9 9.9 2.0 4.1 15.3 7.9 1.4 36.8 9.5 1.7 19.5 19.0 23.8 2.4 6.6 3.3 30.8 11.8 1.6 5.1 1.5 5.7 2.3 16.4 8.6 9.9 4.9 6.4 4.8 2.3 1.2 3.1 3.0 9.6 2.4 5.6 57.6 11.3 2.8 3.7 0.0 3.0 2.9 1.0 0.5 8.2 52.4 14.2 2.5 0.7 4.9 0.8 6.6 7.3 9.4 0.0 0.0 5.8 0.8 0.2 1.3 1.2 10.8 2.9 0.6 30.0 0.1 0.6 28.9 0.3 1.5 1.1 11.9 0.4 9.0 7.8 0.2 8.0 10.8 0.3 0.1 0.6 0.1 13.6 8.0 7.5 0.3 12.6 21.5 5.3 9.9 5.2 8.7 4.4 4.0 25.6 2.0 39.5 5.6 5.6 9.8 4.8 5.2 4.1 0.7 0.1 5.5 0.4 3.2 11.5 10.9 1.0 0.3 4.1 3.3 51.4 14.2 52.4 0.6 10.3 0.4 0.5 0.2 0.7 8.2 0.4 0.5 0.7 3.3 2.5 7.2 1.4 0.1 4.9 27.8 37.0 12.3 22.3 19.5 19.0 30.8 11.8 16.4 11.3 ASS1 "ASS, CTLN1" ENSG00000130707 "Argininosuccinate synthase 1" P00966 9 130444929-130501274 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Ligase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 121.5;liver: 309.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 86.6;HaCaT: 82.0;hTCEpi: 79.7;RPMI-8226: 132.8;THP-1: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15 "plasmacytoid DC: 4.6" "Lineage enriched" "Detected in single" 46 "dendritic cells: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020896, HPA020934" Enhanced Approved Nucleoplasm,Cytosol 4500000 Cytosol Nucleoplasm "HPA020896: AB_1845117, HPA020934: AB_1845118" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (2.78e-1)" "prognostic unfavourable (8.14e-9)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" "unprognostic (2.93e-2)" "unprognostic (3.71e-2)" "unprognostic (3.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.02e-2)" "unprognostic (4.24e-2)" "unprognostic (2.92e-3)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (3.14e-1)" "unprognostic (4.72e-3)" 20.6 15.4 4.6 7.1 4.1 0.0 15.7 2.3 5.4 8.3 18.5 3.5 33.9 11.9 12.0 12.6 9.4 16.6 14.0 11.4 3.8 5.7 121.5 309.9 8.0 2.2 3.2 4.3 11.4 7.9 0.5 4.6 8.7 4.5 12.1 16.8 10.7 26.3 40.6 7.4 12.5 26.8 5.9 3.4 2.7 5.2 8.7 2.2 0.8 17.5 7.0 4.5 17.7 8.6 0.0 4.6 0.0 0.0 0.0 0.0 0.0 11.6 1.1 1.3 2.2 8.8 22.5 4.2 13.9 86.6 2.7 8.4 4.9 3.2 0.0 9.4 28.6 82.0 5.7 0.5 1.9 2.0 2.6 0.0 1.8 12.7 30.7 1.7 0.1 14.8 79.7 4.4 8.0 0.1 0.4 51.7 2.7 57.6 0.6 24.3 1.8 2.5 0.1 1.5 132.8 7.6 5.8 33.4 0.5 49.5 52.2 3.9 35.8 99.5 0.0 1.1 6.9 0.2 1.2 8.6 8.2 2.9 21.8 12.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 4.6 4.1 2.3 5.4 3.8 5.7 3.2 4.3 4.5 2.2 ASTL "ovastacin, SAS1B" ENSG00000188886 "Astacin like metalloendopeptidase" Q6HA08 2 96123850-96138436 "Enzymes, Predicted secreted proteins" Fertilization "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5" "Cell line enhanced" "Detected in some" "BEWO: 3.1;fHDF/TERT166: 2.1;RT4: 3.8" "Low cancer specificity" "Detected in single" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 5 "NK-cells: 1.9;T-cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA015620 Uncertain "Secreted in female reproductive system" "HPA015620: AB_1845121" "unprognostic (3.21e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-2)" "unprognostic (3.45e-4)" "unprognostic (1.00e-2)" "unprognostic (3.03e-2)" "unprognostic (3.53e-2)" "unprognostic (5.12e-2)" "unprognostic (3.62e-1)" "unprognostic (3.40e-1)" "unprognostic (1.95e-1)" "unprognostic (2.61e-5)" "unprognostic (3.41e-3)" "unprognostic (1.08e-1)" "unprognostic (1.67e-1)" "unprognostic (9.93e-3)" 0.2 0.1 0.2 0.6 0.4 8.5 0.1 1.3 0.8 0.0 0.5 0.1 0.3 0.4 0.5 0.0 0.4 0.0 0.8 0.0 0.1 0.0 0.5 1.1 0.0 0.2 0.0 0.0 0.8 0.0 0.9 0.2 0.6 2.7 0.0 2.3 1.1 0.0 0.0 2.3 0.2 0.7 0.0 0.7 3.2 0.0 0.3 0.0 0.0 0.0 1.9 1.8 0.3 0.0 0.0 0.0 0.1 0.0 0.4 3.1 0.0 0.0 0.0 0.1 1.2 0.1 0.1 1.2 2.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 1.1 0.9 0.7 0.0 0.0 0.0 0.4 0.0 3.8 0.8 0.0 0.0 0.3 0.3 1.4 0.5 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.0 0.5 0.0 1.2 0.3 1.8 1.8 0.0 0.0 0.3 0.6 0.0 1.9 0.0 0.0 0.0 0.3 ATAD1 FLJ14600 ENSG00000138138 "ATPase family, AAA domain containing 1" Q8NBU5 10 87751512-87841343 "Enzymes, Predicted membrane proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037569 Uncertain Approved Nucleoli,Mitochondria Nucleoli Mitochondria "HPA037569: AB_10672496" "unprognostic (9.92e-2)" "unprognostic (2.90e-1)" "unprognostic (4.05e-2)" "unprognostic (2.68e-1)" "unprognostic (3.24e-2)" "unprognostic (6.60e-3)" "unprognostic (3.38e-1)" "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (8.45e-2)" "unprognostic (1.35e-3)" "unprognostic (1.67e-2)" "prognostic favourable (3.98e-6)" "unprognostic (2.35e-1)" "unprognostic (3.29e-1)" "unprognostic (3.45e-2)" "unprognostic (4.22e-2)" 16.2 21.3 20.4 15.1 26.2 8.0 19.4 22.4 29.8 19.2 15.9 14.4 16.0 13.5 19.6 17.0 17.3 14.8 13.3 39.9 20.4 22.2 20.6 22.1 14.1 14.2 20.4 17.1 19.1 12.6 25.6 24.9 30.2 31.2 24.3 18.4 19.8 15.8 20.4 32.1 14.4 14.1 18.4 18.2 12.5 14.0 19.8 14.7 18.0 20.1 18.5 15.7 18.9 15.2 9.0 7.3 6.7 7.6 9.8 13.5 7.4 9.8 9.3 11.9 11.3 14.4 12.7 9.0 10.0 16.6 10.3 11.6 8.4 28.6 9.5 7.7 8.3 16.4 9.9 8.5 12.1 8.5 13.4 7.8 13.0 10.3 17.1 21.2 5.4 12.6 23.8 10.9 27.1 6.8 7.6 12.4 11.4 6.0 13.6 14.4 8.8 6.5 9.3 7.6 10.4 15.8 7.6 7.6 16.6 8.8 6.3 20.1 16.5 10.0 8.4 9.4 8.4 6.3 13.0 16.7 15.3 12.2 10.4 14.8 7.2 6.7 3.8 5.7 9.2 5.9 13.5 9.0 10.3 11.4 7.3 7.6 11.8 11.6 2.2 9.8 7.6 5.5 9.3 7.4 20.4 26.2 22.4 29.8 20.4 22.2 20.4 17.1 31.2 14.7 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family, AAA domain containing 2" Q6PL18 8 123319850-123416350 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 53.8" "Cell line enhanced" "Detected in many" "SK-BR-3: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB056158: , HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavourable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavourable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 4.1 4.9 4.6 12.6 9.2 22.8 7.2 5.6 6.9 14.0 8.6 1.5 13.4 5.3 4.7 5.0 10.7 4.7 3.5 13.7 4.2 6.3 2.2 10.1 9.8 13.7 4.0 4.3 9.9 3.9 3.5 18.7 5.2 4.0 11.4 7.5 2.4 6.8 15.4 13.8 7.2 6.6 5.5 4.1 8.8 6.9 20.2 3.4 53.8 4.8 6.3 12.7 9.9 5.9 4.3 2.3 7.2 2.8 4.0 7.4 1.8 25.0 9.8 13.9 4.7 2.5 3.2 6.1 19.7 6.8 17.0 19.0 7.4 10.9 16.4 6.0 6.2 12.0 18.6 6.3 27.3 22.8 9.9 29.5 10.5 15.0 1.0 10.8 14.6 1.0 0.9 16.1 5.4 5.2 13.8 16.8 12.6 26.0 30.9 8.1 2.5 9.8 16.2 16.6 8.9 6.0 11.5 17.9 7.8 28.5 74.4 5.0 15.1 10.2 3.2 12.9 17.8 10.2 23.6 5.4 9.6 15.2 8.4 18.1 10.1 7.2 1.5 5.4 2.9 1.3 4.0 4.3 4.2 4.8 2.3 2.8 2.8 3.0 0.4 4.0 2.8 0.3 7.4 1.8 4.6 9.2 5.6 6.9 4.2 6.3 4.0 4.3 4.0 3.4 ATAT1 "C6orf134, Em:AB023049.7, FLJ13158, MEC17" ENSG00000137343 "Alpha tubulin acetyltransferase 1" Q5SQI0 6 30626842-30646823 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 10.9;AN3-CA: 8.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046816, HPA050999" Approved Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" "Golgi apparatus, Cytosol" "HPA046816: , HPA050999: " "unprognostic (3.98e-1)" "unprognostic (3.18e-1)" "unprognostic (4.30e-2)" "unprognostic (2.67e-2)" "unprognostic (8.86e-2)" "unprognostic (8.18e-3)" "prognostic unfavourable (1.03e-5)" "unprognostic (1.49e-2)" "unprognostic (5.39e-2)" "unprognostic (2.37e-2)" "unprognostic (1.29e-3)" "unprognostic (1.25e-2)" "prognostic unfavourable (7.78e-5)" "unprognostic (2.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.02e-1)" "prognostic favourable (1.35e-4)" 4.8 3.8 16.8 5.4 16.8 4.4 4.1 12.5 20.7 5.5 4.9 16.3 3.0 4.6 10.2 21.0 3.2 8.3 5.4 3.9 15.7 15.9 4.4 3.8 3.9 4.8 14.0 12.2 10.1 4.4 4.4 10.6 4.3 13.0 9.8 5.3 4.1 5.4 4.0 4.5 6.9 6.1 4.9 13.5 4.3 7.9 7.0 12.8 3.3 4.3 1.7 5.6 4.0 3.8 1.7 2.6 2.6 1.7 0.7 2.1 0.8 2.0 1.1 10.9 8.1 1.5 1.1 0.4 0.3 0.1 0.4 0.8 2.9 2.1 0.3 1.7 1.7 2.4 4.0 1.4 0.1 1.5 4.7 0.1 0.4 2.7 0.7 0.2 1.3 2.2 0.9 0.7 0.0 0.9 1.6 0.2 2.0 1.8 1.6 0.7 0.7 0.2 0.9 0.3 0.6 2.0 3.0 0.6 4.3 0.7 1.0 0.7 4.4 0.5 0.8 3.1 2.2 0.1 0.8 1.6 2.1 1.0 2.5 4.8 3.2 2.6 1.7 1.3 0.8 1.5 1.0 1.7 1.0 0.8 1.6 1.2 2.1 1.6 0.3 0.7 1.1 2.6 0.9 0.8 16.8 16.8 12.5 20.7 15.7 15.9 14.0 12.2 13.0 12.8 ATE1 ENSG00000107669 "Arginyltransferase 1" O95260 10 121740421-121928801 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038444, HPA057549" Approved Supported Nucleoplasm Nucleoplasm "HPA038444: AB_10672745, HPA057549: " "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (2.75e-3)" "unprognostic (2.40e-1)" "unprognostic (4.67e-2)" "unprognostic (6.65e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-1)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "prognostic favourable (2.67e-4)" "unprognostic (3.20e-1)" "unprognostic (8.08e-2)" "unprognostic (2.16e-1)" "unprognostic (1.02e-1)" 15.4 16.9 14.6 16.8 18.8 14.7 16.9 23.1 20.8 17.4 18.8 17.6 12.6 13.5 14.4 14.3 15.7 13.6 14.4 27.5 15.0 18.4 23.1 23.0 14.0 11.7 17.6 14.0 14.4 13.4 23.6 22.5 15.0 15.4 16.5 20.0 19.0 14.1 16.6 33.6 12.0 16.2 25.8 15.6 12.9 12.0 18.1 14.6 21.4 22.0 11.2 14.3 22.8 15.2 14.0 14.4 17.1 11.5 9.9 16.0 8.5 9.8 16.8 13.0 11.0 9.0 10.8 8.9 8.7 15.6 10.4 11.0 21.7 12.2 12.1 7.2 9.9 10.1 12.1 8.6 10.1 20.0 10.7 4.3 7.3 17.6 9.2 18.6 10.2 7.9 8.0 10.8 22.9 11.2 6.7 25.2 8.3 6.2 10.1 7.6 6.7 8.1 9.8 13.7 7.1 13.2 8.5 3.7 12.2 11.7 8.3 17.9 6.1 4.7 13.8 6.0 5.9 8.9 15.4 21.9 30.2 14.8 9.3 12.9 5.0 17.1 11.1 14.7 16.0 11.1 15.5 13.0 13.9 13.7 9.4 14.0 15.7 14.3 8.1 9.9 11.5 14.4 13.6 8.5 14.6 18.8 23.1 20.8 15.0 18.4 17.6 14.0 15.4 14.6 ATF2 "CRE-BP1, CREB2, HB16, TREB7" ENSG00000115966 "Activating transcription factor 2" P15336 2 175072250-175168382 "Enzymes, Predicted intracellular proteins, Transcription factors" "DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003769, HPA022134" Supported Enhanced Nucleoplasm Nucleoplasm "CAB003769: AB_562241, HPA022134: AB_1845138" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (9.81e-2)" "unprognostic (1.93e-1)" "unprognostic (9.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavourable (7.08e-5)" "unprognostic (2.28e-2)" "unprognostic (3.70e-2)" "unprognostic (6.47e-2)" "unprognostic (7.17e-2)" "unprognostic (4.02e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (7.21e-3)" "unprognostic (6.70e-2)" 25.3 21.0 25.3 14.3 29.3 14.3 19.7 39.6 33.4 27.5 15.9 18.0 15.7 12.8 22.4 22.6 16.0 19.5 17.9 14.1 25.1 28.0 23.0 26.8 15.2 17.6 23.2 18.4 27.3 19.0 24.0 33.0 19.9 29.6 19.0 16.0 14.9 16.8 19.1 13.9 10.1 13.2 18.3 22.9 17.5 13.8 19.9 18.9 34.6 32.6 10.2 20.1 21.7 16.7 15.0 18.7 24.2 14.8 15.3 22.0 14.3 7.2 6.4 19.0 12.3 17.0 18.2 8.8 11.9 20.4 14.5 21.0 13.8 13.6 10.9 13.1 14.0 7.1 14.4 7.2 22.7 13.5 8.3 15.4 11.7 30.0 19.1 14.2 16.2 13.6 16.3 18.6 22.2 19.9 12.5 17.1 16.2 5.5 23.0 17.8 17.7 14.6 20.1 8.8 16.9 21.2 6.4 15.8 13.1 14.9 4.6 17.5 10.4 15.9 12.5 16.9 8.8 9.0 7.1 16.3 24.6 14.0 13.2 13.6 11.4 24.2 14.4 16.8 18.2 12.8 22.0 15.0 15.7 18.8 18.7 12.7 18.3 19.9 9.3 15.3 14.8 10.5 19.8 14.3 25.3 29.3 39.6 33.4 25.1 28.0 23.2 18.4 29.6 18.9 ATG4A "APG4A, AUTL2" ENSG00000101844 "Autophagy related 4A cysteine peptidase" Q8WYN0 X 108091668-108154671 "Enzymes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036374, HPA064759" Uncertain Approved "Actin filaments,Microtubules" Microtubules "Actin filaments" "HPA036374: AB_10672354, HPA064759: " "prognostic unfavourable (1.36e-5)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.52e-1)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "unprognostic (2.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.14e-1)" "unprognostic (2.62e-2)" "unprognostic (4.09e-1)" "unprognostic (1.03e-3)" "unprognostic (7.53e-2)" "unprognostic (2.98e-1)" "unprognostic (5.02e-3)" "unprognostic (1.20e-2)" 8.2 11.8 6.4 6.1 8.0 6.1 7.4 9.7 6.2 6.8 10.0 5.5 8.6 10.3 6.9 10.4 10.6 5.4 6.5 10.9 4.3 3.2 15.3 23.4 10.8 8.2 6.9 5.7 4.7 22.3 8.2 13.1 7.9 7.2 6.6 11.3 6.7 17.2 6.2 18.8 6.3 18.7 7.2 6.7 10.5 12.9 3.1 8.2 12.0 12.0 7.4 10.5 7.4 7.8 8.7 9.8 18.7 9.9 10.0 11.9 7.4 5.8 2.9 1.9 3.6 18.4 6.3 2.3 8.2 5.1 4.2 5.0 2.3 3.3 6.4 7.4 6.5 2.8 5.5 6.0 6.4 10.8 6.1 2.7 5.1 1.5 4.0 5.7 8.9 6.5 6.3 5.2 2.1 40.1 8.3 20.5 7.7 5.3 5.4 5.3 3.5 8.4 3.7 3.2 9.3 6.2 5.2 2.7 2.1 5.2 6.4 3.4 3.2 5.3 11.0 2.5 1.2 9.0 4.4 9.5 10.8 6.9 5.2 6.6 3.7 18.7 7.0 13.1 11.6 9.9 8.3 8.7 8.9 10.9 9.8 7.6 7.0 11.9 2.2 10.0 6.7 4.6 9.2 7.4 6.4 8.0 9.7 6.2 4.3 3.2 6.9 5.7 7.2 8.2 ATG4B "Apg4B, AUTL1, DKFZp586D1822, KIAA0943" ENSG00000168397 "Autophagy related 4B cysteine peptidase" Q9Y4P1 2 241637213-241673857 "Enzymes, Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037195, HPA069803" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB037195: AB_1078237, HPA069803: " "unprognostic (1.51e-1)" "unprognostic (8.80e-2)" "prognostic unfavourable (6.85e-4)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "unprognostic (2.67e-3)" "unprognostic (1.07e-3)" "unprognostic (1.06e-1)" "unprognostic (1.61e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-3)" "unprognostic (3.02e-2)" "prognostic unfavourable (2.79e-4)" "unprognostic (2.60e-1)" "unprognostic (6.63e-2)" "unprognostic (1.66e-1)" "prognostic favourable (9.64e-4)" 10.9 16.5 19.6 16.6 21.3 31.3 15.1 34.8 25.7 13.5 18.7 21.7 23.2 14.6 33.5 24.0 26.7 17.7 18.8 19.5 20.5 21.5 17.2 15.5 15.8 19.4 29.2 19.7 17.3 19.2 18.7 27.4 15.4 20.3 20.5 18.9 20.8 22.8 14.2 17.2 26.6 21.1 18.9 23.1 18.7 15.5 28.0 21.4 21.2 18.2 7.3 21.9 15.3 14.4 16.5 20.3 18.9 18.6 11.4 19.6 16.8 8.6 13.4 19.2 14.9 19.3 14.1 19.1 12.7 13.8 16.4 13.6 14.7 15.3 6.6 5.7 22.7 12.7 18.3 24.1 16.0 14.1 18.6 19.5 21.7 31.8 25.1 11.2 11.0 13.9 16.8 18.4 17.8 16.9 16.6 10.2 18.6 21.1 20.2 19.9 22.4 14.4 34.8 17.7 10.0 12.9 28.0 19.3 13.4 10.8 14.4 15.1 15.9 16.6 18.4 15.7 10.7 10.4 13.6 11.5 12.0 25.4 19.0 14.1 14.6 4.6 18.6 18.9 18.7 15.5 15.5 15.7 15.2 16.5 20.3 16.5 19.6 14.7 14.8 11.4 16.2 16.3 19.3 16.8 19.6 21.3 34.8 25.7 20.5 21.5 29.2 19.7 20.3 21.4 ATG4C "APG4C, AUTL1, AUTL3, FLJ14867" ENSG00000125703 "Autophagy related 4C cysteine peptidase" Q96DT6 1 62784135-62865513 "Enzymes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007049 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA007049: AB_1845159" "unprognostic (1.28e-1)" "unprognostic (2.69e-1)" "prognostic favourable (9.83e-4)" "unprognostic (7.43e-2)" "unprognostic (1.17e-1)" "unprognostic (1.70e-1)" "unprognostic (3.76e-2)" "unprognostic (8.36e-2)" "unprognostic (1.83e-2)" "unprognostic (1.30e-1)" "unprognostic (3.77e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-2)" "unprognostic (1.81e-1)" "unprognostic (4.17e-2)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" 8.8 9.8 19.4 11.3 32.8 6.0 9.2 16.7 23.4 10.6 9.5 29.8 7.2 7.7 9.6 7.2 8.6 8.0 10.4 7.2 23.7 15.5 13.5 12.6 9.2 13.7 42.6 16.5 10.3 11.2 15.5 11.3 15.0 22.4 8.0 10.6 4.9 10.8 8.0 6.4 6.3 7.8 11.2 26.5 13.3 8.6 8.9 40.4 11.0 12.0 3.7 12.4 13.4 6.8 20.6 19.4 16.0 10.9 7.0 9.4 6.7 7.6 6.1 9.5 8.3 12.5 13.5 9.5 11.5 7.8 11.1 12.5 4.5 6.1 16.3 8.9 5.8 5.9 11.3 8.7 16.1 12.2 10.4 18.3 6.5 5.8 8.9 14.8 12.3 11.1 6.2 11.8 5.6 13.3 15.5 13.3 9.3 3.6 14.9 5.7 13.9 10.1 17.9 22.8 11.5 8.0 5.6 12.9 6.5 7.6 14.4 14.8 7.0 7.0 5.2 8.9 8.7 15.0 12.6 11.6 15.6 13.3 10.2 14.7 10.7 16.0 10.9 8.5 4.8 8.8 6.6 20.6 6.6 5.6 19.4 19.1 9.4 7.7 1.6 7.0 5.0 11.6 5.7 6.7 19.4 32.8 16.7 23.4 23.7 15.5 42.6 16.5 22.4 40.4 ATG4D "APG4-D, APG4D, AUTL4" ENSG00000130734 "Autophagy related 4D cysteine peptidase" Q86TL0 19 10543895-10553418 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA067683 Approved Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA067683: " "unprognostic (2.85e-1)" "prognostic favourable (3.18e-5)" "unprognostic (2.73e-1)" "unprognostic (3.67e-1)" "unprognostic (2.18e-1)" "unprognostic (1.15e-2)" "unprognostic (3.52e-2)" "unprognostic (1.23e-1)" "unprognostic (4.28e-2)" "unprognostic (7.30e-2)" "prognostic favourable (9.95e-4)" "unprognostic (1.52e-1)" "prognostic favourable (2.39e-7)" "prognostic favourable (5.03e-4)" "unprognostic (3.78e-2)" "unprognostic (2.29e-1)" "unprognostic (3.18e-3)" 6.4 10.8 5.1 9.2 7.8 35.0 6.3 15.6 14.9 6.2 18.4 9.8 8.1 26.0 6.1 7.2 18.4 5.5 7.6 15.4 4.6 4.9 14.5 8.8 7.3 9.8 9.6 6.4 7.0 16.1 8.2 12.1 6.9 7.3 9.7 7.3 7.8 11.5 8.5 31.5 17.7 27.3 4.0 4.5 12.0 10.5 29.0 8.8 19.9 9.8 16.4 10.5 7.5 9.6 2.0 7.6 5.7 1.6 2.2 3.6 1.4 6.9 4.7 6.5 8.8 1.2 1.0 5.1 4.3 4.3 6.1 6.8 7.8 2.3 4.5 8.2 0.5 11.0 4.0 3.7 0.8 4.4 10.6 11.9 11.4 4.3 4.1 4.7 12.2 1.0 7.7 5.3 1.9 1.8 8.8 10.9 1.9 11.2 14.0 29.1 9.9 12.8 10.3 4.0 8.0 3.5 9.4 24.6 9.5 6.3 12.4 4.9 7.6 11.7 3.4 9.4 5.9 18.9 9.5 9.7 6.6 5.3 8.0 9.3 10.6 3.0 1.6 5.7 2.1 1.5 3.1 2.0 2.5 2.3 1.1 1.0 2.5 3.4 0.5 2.2 0.7 7.6 3.6 1.4 5.1 7.8 15.6 14.9 4.6 4.9 9.6 6.4 7.3 8.8 ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311817-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Enhanced "Plasma membrane,Cytosol" 3400000 "Plasma membrane, Cytosol" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavourable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavourable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" 19.4 27.4 21.1 23.0 28.4 16.9 24.8 12.1 32.3 20.6 26.7 29.1 18.1 23.4 27.9 15.6 19.1 21.9 19.1 18.2 20.3 21.1 23.1 35.6 17.3 36.1 29.7 19.9 23.4 32.9 25.1 21.1 31.1 24.4 21.9 35.9 19.5 14.4 29.4 35.5 17.0 20.6 26.7 21.7 29.0 20.4 15.0 28.0 46.3 16.1 13.5 35.3 27.6 18.0 21.7 13.4 2.9 8.9 19.6 22.8 10.0 20.2 30.7 17.1 29.1 23.0 23.3 8.6 20.7 18.0 23.7 27.2 59.1 31.8 29.5 25.7 21.6 21.3 37.6 31.2 34.0 21.9 36.4 35.9 26.3 53.0 29.8 44.9 18.4 19.7 24.0 31.6 38.2 15.8 46.3 24.6 32.5 29.9 39.1 21.8 65.9 17.2 36.4 24.7 26.4 25.1 32.7 26.9 18.6 16.6 20.5 23.4 33.6 16.0 13.9 20.1 20.8 25.9 13.0 31.1 40.6 61.2 17.5 25.1 29.0 2.9 6.0 0.1 13.2 8.9 22.8 21.7 18.6 20.0 13.4 13.2 18.9 17.5 0.7 19.6 7.4 11.7 17.7 10.0 21.1 28.4 12.1 32.3 20.3 21.1 29.7 19.9 24.4 28.0 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222484-108369102 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Enhanced Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "CAB000102: , HPA067142: " "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 8.3 10.9 12.7 26.5 19.3 16.8 9.4 17.7 14.4 10.9 8.5 10.9 8.8 6.0 11.2 11.4 6.9 9.5 9.2 9.6 12.4 8.5 7.7 9.5 10.1 33.4 19.6 6.7 20.5 20.7 15.7 29.2 8.8 14.5 9.1 7.9 7.2 15.1 9.8 6.2 8.4 16.5 10.6 23.4 22.6 8.9 6.1 17.9 19.5 10.7 5.1 26.9 10.7 10.7 13.7 6.1 13.5 12.5 7.6 18.5 4.4 2.6 3.8 7.5 4.0 9.8 14.3 1.9 6.0 6.7 3.5 5.8 4.7 6.3 9.4 8.9 4.8 4.0 5.7 5.0 5.4 7.5 3.3 8.5 4.7 4.7 5.1 10.2 9.2 9.2 3.1 5.2 10.2 7.2 8.2 6.4 6.8 1.9 7.0 9.4 6.1 3.8 5.5 5.2 14.8 3.9 5.4 5.1 6.3 6.9 3.2 10.3 4.9 5.8 11.3 8.6 4.8 4.9 5.6 4.3 4.5 47.4 5.7 11.3 9.6 13.5 5.7 3.8 14.9 5.3 10.4 11.1 10.5 11.3 2.7 13.7 18.5 17.9 10.8 7.6 12.5 6.1 5.3 4.4 12.7 19.3 17.7 14.4 12.4 8.5 19.6 6.7 14.5 17.9 ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677273-25865172 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 12.8;fHDF/TERT166: 18.7;HMC-1: 12.5;RPTEC TERT1: 10.0;SK-MEL-30: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 12 "dendritic cells: 3.0;NK-cells: 4.7;T-cells: 4.0" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain "HPA041496: , HPA042509: " "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" 7.4 14.1 5.3 5.4 9.8 4.7 5.7 3.4 11.0 5.3 3.3 6.2 1.4 1.5 1.9 2.1 3.7 3.1 7.1 2.9 8.0 5.8 6.0 1.0 12.2 14.8 9.3 9.0 1.6 1.9 1.9 2.5 3.6 11.3 3.6 2.3 4.0 14.4 1.5 0.7 3.3 3.6 5.3 6.4 3.5 4.0 6.0 6.2 1.5 3.0 1.6 3.3 4.2 3.3 0.0 3.0 0.0 0.3 4.7 4.0 1.7 0.0 3.3 0.6 0.0 2.7 2.5 0.0 12.8 6.2 3.9 6.9 0.0 0.0 0.0 0.7 18.7 0.0 6.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.6 0.0 0.5 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.9 0.7 2.3 2.3 0.8 10.0 0.0 0.0 0.0 0.0 0.0 16.9 5.1 0.5 0.0 5.2 0.2 7.5 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.3 0.0 1.9 0.2 1.9 0.0 2.2 2.1 0.4 0.0 4.0 3.7 0.0 4.7 0.1 3.0 0.7 1.7 5.3 9.8 3.4 11.0 8.0 5.8 9.3 9.0 11.3 6.2 ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.8;intestine: 35.4" "Cell line enriched" "Detected in single" 23 "WM-115: 17.4" "Group enriched" "Detected in many" 7 "colorectal cancer: 19.0;pancreatic cancer: 4.2;stomach cancer: 8.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034574 Uncertain "HPA034574: AB_10669992" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.47e-4)" "unprognostic (3.99e-2)" "unprognostic (6.10e-3)" "unprognostic (4.69e-2)" "unprognostic (4.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-2)" "unprognostic (3.42e-2)" "unprognostic (5.12e-2)" "unprognostic (2.38e-3)" "unprognostic (5.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-1)" "unprognostic (2.14e-1)" 0.5 0.4 4.3 4.1 9.4 0.4 0.7 5.1 10.0 1.7 33.8 27.8 1.5 18.9 0.4 11.4 8.2 0.7 12.8 0.5 5.5 2.8 0.5 0.4 0.5 0.4 13.8 6.8 0.4 4.2 0.4 0.4 0.4 13.1 0.5 35.4 0.0 2.8 1.0 0.4 8.4 21.1 1.6 20.2 0.4 4.1 0.7 14.0 0.0 0.5 0.0 2.5 1.8 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 9.4 5.1 10.0 5.5 2.8 13.8 6.8 13.1 14.0 ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485288-47593486 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 55.7" "Cell line enhanced" "Detected in many" "HAP1: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "basophil: 31.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 31.5" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA050808: " "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.93e-2)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-2)" "unprognostic (8.05e-2)" "unprognostic (3.48e-2)" "unprognostic (3.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "prognostic favourable (5.00e-8)" "unprognostic (3.97e-2)" "unprognostic (4.47e-3)" "unprognostic (1.11e-2)" "unprognostic (3.37e-2)" 8.1 9.7 7.6 6.8 8.0 1.4 6.9 3.9 7.5 10.2 7.4 5.2 10.4 4.5 12.9 10.1 15.2 6.7 8.6 7.4 7.3 4.0 14.5 5.8 9.4 6.7 7.0 4.8 10.0 6.2 16.9 18.6 55.7 8.1 8.1 4.5 7.7 7.5 11.5 2.8 14.8 6.0 11.4 8.9 12.7 7.6 3.9 7.3 3.6 10.7 5.4 9.2 9.9 13.1 3.6 1.8 31.5 2.9 1.0 0.9 0.6 1.5 1.0 2.4 1.6 6.8 7.4 0.4 10.5 12.7 5.0 9.1 5.4 9.0 4.7 3.9 16.9 2.7 24.5 8.8 7.8 1.8 1.9 3.7 1.7 0.3 6.0 1.1 2.3 6.3 6.7 9.8 6.6 8.5 0.0 2.5 13.7 0.5 2.5 0.7 0.8 1.3 2.8 5.3 0.0 9.1 1.8 1.6 2.9 4.9 1.2 3.1 2.2 1.2 12.8 12.5 2.5 1.1 4.5 1.1 0.8 0.0 6.1 6.9 4.0 31.5 1.4 0.1 0.6 2.3 0.9 1.3 0.2 0.3 1.8 3.6 0.0 0.4 0.7 1.0 2.9 1.1 0.3 0.6 7.6 8.0 3.9 7.5 7.3 4.0 7.0 4.8 8.1 7.3 ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690329-112887168 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Enhanced Vesicles Vesicles "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favourable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" 11.1 11.5 7.2 8.3 16.4 15.7 7.9 5.0 12.5 13.6 5.8 24.4 8.7 9.5 13.7 9.2 8.5 10.8 14.6 19.6 7.2 5.4 12.9 12.3 36.9 7.5 17.7 6.9 8.6 13.2 36.1 17.8 11.2 12.8 5.0 3.6 10.0 12.0 9.0 11.2 11.4 8.7 9.1 12.5 10.2 6.1 9.7 16.2 2.1 16.4 6.4 6.0 5.7 11.3 4.2 1.1 6.4 3.1 0.0 1.0 0.6 13.8 7.1 9.0 10.6 4.6 6.2 16.1 6.6 3.9 5.7 4.6 22.3 16.1 7.0 8.1 5.6 11.8 8.1 5.5 5.5 7.0 7.6 8.1 5.9 11.6 7.3 15.2 13.3 4.2 4.2 6.8 4.2 14.8 5.6 1.2 3.9 5.2 6.9 9.6 3.9 5.1 6.0 3.6 4.0 30.9 3.2 14.5 4.0 6.4 8.4 5.5 3.2 20.3 9.7 0.0 12.3 7.3 5.0 3.8 7.5 2.9 2.5 14.3 6.2 0.0 2.3 3.1 1.0 3.1 0.6 1.3 0.6 0.5 1.1 4.2 0.7 0.4 6.4 0.0 2.7 1.1 0.1 0.6 7.2 16.4 5.0 12.5 7.2 5.4 17.7 6.9 12.8 16.2 ATP11B "ATPIF, ATPIR, KIAA0956" ENSG00000058063 "ATPase phospholipid transporting 11B (putative)" Q9Y2G3 3 182793500-182921635 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036237, HPA036238" Uncertain Approved "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "HPA036237: AB_10673123, HPA036238: AB_10670792" "unprognostic (4.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "prognostic unfavourable (3.44e-4)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (6.73e-2)" "unprognostic (2.03e-3)" "unprognostic (7.28e-2)" "unprognostic (1.18e-1)" "prognostic unfavourable (1.09e-4)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (3.22e-1)" "unprognostic (8.66e-2)" "unprognostic (1.35e-1)" 16.8 7.9 7.7 19.7 9.8 35.4 17.0 18.4 9.4 20.5 21.6 8.9 14.3 13.6 15.0 11.7 37.3 11.8 12.7 21.1 6.9 5.9 13.7 14.3 19.4 20.3 10.3 5.7 15.2 14.6 21.0 26.0 8.0 8.3 16.8 16.9 9.8 19.7 13.8 13.1 21.8 22.8 16.5 11.3 23.4 27.6 22.8 8.9 49.0 10.8 20.4 21.9 22.7 25.5 3.6 4.2 7.5 1.8 3.0 3.4 1.3 22.2 3.2 7.0 9.8 15.0 16.4 6.5 10.3 14.2 8.0 9.4 7.9 11.6 10.3 17.7 14.8 13.5 8.4 10.6 14.0 22.9 6.7 24.9 4.3 1.7 8.8 19.6 16.0 11.1 12.0 9.0 13.1 12.6 8.8 32.3 12.9 7.5 16.3 6.3 5.0 6.3 6.8 20.6 12.4 9.7 18.8 4.2 7.6 28.7 3.7 12.5 4.0 14.6 12.3 12.2 13.3 10.5 17.9 44.1 39.4 19.4 8.4 8.4 7.1 7.5 1.7 7.2 3.1 1.8 3.0 3.6 2.7 3.1 1.9 2.4 2.3 3.4 6.8 3.0 1.7 4.2 2.0 1.3 7.7 9.8 18.4 9.4 6.9 5.9 10.3 5.7 8.3 8.9 ATP11C "ATPIG, ATPIQ" ENSG00000101974 "ATPase phospholipid transporting 11C" Q8NB49 X 139726346-139945276 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030830 Approved "HPA030830: AB_10601336" "unprognostic (8.94e-2)" "unprognostic (1.00e-2)" "unprognostic (3.06e-2)" "unprognostic (3.42e-3)" "unprognostic (3.08e-1)" "unprognostic (3.46e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (3.65e-2)" "unprognostic (9.75e-2)" "unprognostic (2.73e-1)" "unprognostic (5.18e-2)" 12.8 7.0 4.8 7.6 10.6 4.6 9.6 8.0 5.8 13.1 8.8 5.3 30.2 4.8 12.0 9.5 7.3 9.1 7.4 5.2 6.7 4.5 10.8 41.4 6.7 11.2 9.6 3.2 13.1 4.6 6.8 4.2 4.6 9.5 11.5 6.4 10.7 5.8 21.4 6.6 5.6 7.8 11.3 6.3 14.4 7.1 7.9 9.7 14.9 6.1 4.0 7.4 12.7 12.2 2.8 2.1 5.1 1.7 3.5 2.5 0.5 9.4 4.0 8.3 13.5 12.4 16.9 10.6 11.3 15.2 9.2 12.8 3.5 7.7 13.6 25.6 16.0 7.9 20.0 5.1 14.5 12.4 11.7 6.8 8.9 6.9 13.8 11.9 4.4 11.1 3.4 9.9 8.5 15.8 7.7 10.4 12.1 5.1 10.9 8.1 14.1 7.7 10.9 9.0 11.3 7.7 15.7 6.5 10.8 4.4 0.5 5.9 3.4 6.6 17.7 12.6 4.1 15.2 15.4 3.0 2.9 10.7 5.7 14.9 6.2 5.1 1.5 0.4 1.2 1.0 2.5 2.8 1.4 1.1 1.2 2.7 1.4 2.2 2.8 3.5 1.7 2.1 1.0 0.5 4.8 10.6 8.0 5.8 6.7 4.5 9.6 3.2 9.5 9.7 ATP12A "#945, 2, ATP1AL1, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680411-24712493 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 12.3;lymphoid tissue: 38.4" "Cell line enhanced" "Detected in some" "HEK 293: 1.2;HEL: 3.2;NTERA-2: 1.0;U-266/84: 2.8;U-937: 1.6" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Cell type enriched" "Detected in single" 5 "T-reg: 1.7" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039526 Approved "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" 0.1 0.1 0.1 0.0 0.1 0.0 0.8 0.2 1.3 0.4 0.1 0.0 0.0 0.0 0.2 0.2 12.3 0.1 0.0 0.1 0.3 0.2 8.8 0.1 6.1 0.0 0.1 0.0 0.1 1.0 0.0 0.2 5.8 0.4 0.3 2.2 0.0 0.4 0.0 0.1 9.8 0.1 0.0 0.1 0.1 0.1 1.0 0.0 1.2 0.2 2.9 38.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.3 0.0 0.5 1.2 3.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 2.8 0.1 0.0 1.6 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.1 0.2 1.3 0.3 0.2 0.1 0.0 0.4 0.0 ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Mental retardation, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 195.4;parathyroid gland: 194.4" "Cell line enhanced" "Detected in all" "SK-MEL-30: 248.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced 380000 "CAB018702: AB_626713, CAB069993: AB_2060979" "unprognostic (6.18e-2)" "unprognostic (2.18e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-1)" "prognostic unfavourable (1.42e-4)" "unprognostic (1.80e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (1.65e-1)" "prognostic favourable (8.98e-8)" "unprognostic (4.75e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-2)" "prognostic unfavourable (4.01e-4)" 17.4 25.6 22.4 16.2 40.3 10.5 26.9 74.2 67.4 17.8 121.9 14.2 56.1 92.3 13.1 38.3 34.9 17.7 65.8 41.1 26.1 18.7 162.7 34.6 35.1 9.6 19.2 27.6 17.4 78.6 194.4 25.0 19.2 34.1 22.1 65.7 24.1 84.4 53.7 19.0 40.5 195.4 17.7 20.7 13.7 25.0 17.0 13.9 9.1 101.2 13.7 16.2 14.2 23.1 10.3 22.0 6.4 29.7 10.4 30.2 17.2 32.9 12.2 12.7 6.3 25.5 24.7 65.2 19.8 39.4 24.4 34.7 48.7 23.7 26.1 28.0 23.4 43.1 25.0 41.7 35.5 9.6 27.7 15.2 23.0 41.1 19.5 38.1 21.4 27.5 69.9 28.4 37.5 29.9 25.0 25.3 21.6 65.6 15.4 13.8 29.8 24.5 14.9 29.6 23.1 88.1 34.0 12.5 11.0 30.7 58.4 248.8 15.3 22.1 26.3 13.9 19.5 35.9 40.0 12.2 9.5 20.1 42.7 22.0 81.6 6.4 13.3 6.1 23.2 20.9 24.8 10.3 26.4 24.9 22.0 5.3 30.2 22.0 1.6 10.4 29.7 11.1 20.3 17.2 22.4 40.3 74.2 67.4 26.1 18.7 19.2 27.6 34.1 13.9 ATP1A2 "FHM2, MHP2" ENSG00000018625 "ATPase Na+/K+ transporting subunit alpha 2" P50993 1 160115759-160143591 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 109.8;skeletal muscle: 305.8" "Cell line enhanced" "Detected in some" "AF22: 32.2;HHSteC: 9.4;RH-30: 10.5;U-87 MG: 6.5" "Cancer enriched" "Detected in many" 18 "glioma: 91.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022230 Enhanced "CAB022230: " "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (3.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.83e-1)" "unprognostic (7.98e-2)" "unprognostic (2.16e-2)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.85e-2)" "unprognostic (8.63e-4)" "unprognostic (1.70e-2)" "unprognostic (9.40e-3)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (7.16e-2)" "unprognostic (5.32e-3)" 12.6 3.9 61.4 2.8 80.1 2.3 6.5 30.4 109.8 4.7 6.6 27.4 2.4 3.7 4.2 7.4 15.3 6.0 5.3 35.4 42.2 27.0 3.3 2.5 3.8 2.4 45.6 37.9 9.9 2.6 2.4 4.6 3.6 58.0 13.8 5.6 12.5 3.1 14.2 305.8 2.8 4.4 5.4 51.5 2.7 2.8 3.9 28.3 0.0 2.6 17.7 2.5 5.5 1.3 0.6 1.4 1.7 0.4 0.6 0.5 0.3 0.0 0.0 32.2 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 2.8 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 1.3 0.4 0.3 0.3 0.3 0.2 0.4 0.3 0.2 0.7 0.6 0.3 0.5 1.7 0.6 0.2 1.4 0.2 0.3 61.4 80.1 30.4 52.0 42.2 27.0 45.6 37.9 58.0 28.3 ATP1A3 DYT12 ENSG00000105409 "ATPase Na+/K+ transporting subunit alpha 3" P13637 19 41966582-41997497 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Deafness, Disease mutation, Dystonia, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 146.4;heart muscle: 78.3" "Cell line enhanced" "Detected in many" "Daudi: 20.4;Karpas-707: 13.0;REH: 12.8;SCLC-21H: 48.3;SH-SY5Y: 20.8" "Group enriched" "Detected in many" 6 "glioma: 21.6;testis cancer: 4.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.2;memory CD8 T-cell: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "CAB033630, HPA045367, HPA056446" Enhanced Approved "CAB033630: AB_781528, HPA045367: , HPA056446: " "unprognostic (1.90e-1)" "unprognostic (8.65e-2)" "unprognostic (4.57e-2)" "unprognostic (8.20e-3)" "unprognostic (8.94e-2)" "unprognostic (2.52e-1)" "unprognostic (3.16e-2)" "unprognostic (7.66e-2)" "unprognostic (8.02e-2)" "prognostic unfavourable (3.44e-4)" "prognostic favourable (6.15e-5)" "unprognostic (4.02e-3)" "prognostic unfavourable (3.02e-6)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "unprognostic (3.45e-1)" "unprognostic (1.27e-1)" 1.9 12.8 34.0 2.5 30.8 2.1 1.8 42.8 146.4 1.8 2.4 4.8 0.0 2.4 1.8 1.8 2.0 1.8 1.9 78.3 48.3 54.6 1.8 1.8 1.9 2.3 39.9 42.6 1.8 2.3 1.8 3.0 1.8 94.4 1.8 2.3 17.3 2.2 1.8 1.8 2.0 2.7 2.2 18.5 2.1 2.0 18.6 6.9 0.0 1.8 0.0 2.1 1.9 0.1 0.3 0.1 0.0 0.0 0.1 2.2 0.3 0.0 0.8 0.2 8.5 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.3 1.6 20.4 0.9 0.1 0.2 6.0 0.0 0.2 3.8 1.1 1.7 0.0 0.1 0.0 0.0 6.7 0.0 0.0 0.0 0.1 0.0 0.0 13.0 0.1 0.3 3.7 0.0 1.1 5.2 12.8 7.0 0.6 0.0 0.2 48.3 20.8 0.1 1.5 0.0 1.2 0.9 0.0 1.1 1.1 0.0 0.3 1.3 0.9 4.6 1.9 7.1 0.1 0.0 0.0 0.0 2.2 0.0 0.2 0.3 0.6 1.7 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.1 0.7 0.3 34.0 30.8 42.8 66.6 48.3 54.6 39.9 42.6 94.4 6.9 ATP23 "KUB3, XRCC6BP1" ENSG00000166896 "ATP23 metallopeptidase and ATP synthase assembly factor homolog" Q9Y6H3 12 57941541-57957269 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 39.5" "Cell line enhanced" "Detected in many" "NB-4: 14.8;RH-30: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035804, HPA043204" Uncertain Enhanced "Vesicles,Plasma membrane,Cell Junctions,Cytosol" "Vesicles, Plasma membrane" "Cell Junctions, Cytosol" "HPA035804: AB_10601026, HPA043204: " "unprognostic (2.56e-1)" "unprognostic (1.31e-2)" "unprognostic (8.82e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (5.28e-2)" "unprognostic (5.41e-3)" "unprognostic (1.03e-2)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "prognostic unfavourable (1.44e-5)" "unprognostic (4.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-1)" 6.7 4.9 4.3 5.2 5.3 11.3 4.8 6.1 4.8 5.6 8.2 1.3 2.5 3.9 3.2 4.2 7.3 3.1 2.4 6.4 4.2 3.6 5.4 6.2 2.7 6.8 2.7 3.8 4.2 5.8 3.2 3.0 3.5 2.9 5.1 8.2 2.3 3.4 3.3 11.7 5.6 4.3 6.5 3.4 3.7 3.8 39.5 2.0 20.8 4.7 5.9 4.7 6.3 6.2 3.0 4.5 12.0 4.5 2.6 5.6 3.0 1.9 1.5 1.9 2.2 2.8 2.7 1.0 1.9 1.9 2.2 2.1 1.2 2.4 6.8 2.4 1.4 1.8 1.8 1.9 3.8 3.4 1.8 4.4 1.2 1.9 1.2 8.9 3.0 1.4 1.5 1.3 0.5 1.5 4.6 4.9 1.8 3.0 4.8 14.8 1.6 3.7 3.1 48.8 2.8 1.8 2.5 1.2 1.8 3.0 2.8 1.5 4.9 8.4 0.8 1.6 2.8 2.1 1.8 4.0 2.1 3.5 1.8 9.6 2.7 7.6 4.5 12.0 3.5 2.4 2.6 3.0 4.0 3.3 4.5 3.0 4.3 4.0 1.9 2.6 4.2 2.1 5.6 3.0 4.3 5.3 6.1 4.8 4.2 3.6 2.7 3.8 2.9 2.0 ATP2A1 "ATP2A, SERCA1" ENSG00000196296 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1" O14983 16 28878405-28904509 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "skeletal muscle: 456.3;tongue: 209.0" "Cell line enhanced" "Detected in many" "HEK 293: 19.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "NK-cell: 4.7" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in single" 8 "thalamus: 14.3" "Low region specificity" "Detected in all" "CAB002310, CAB032706" Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB002310: AB_564139, CAB032706: AB_2061286" "unprognostic (2.37e-1)" "unprognostic (6.81e-2)" "unprognostic (2.23e-5)" "unprognostic (5.35e-2)" "unprognostic (2.27e-1)" "unprognostic (2.04e-1)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.87e-1)" "unprognostic (5.22e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-4)" "unprognostic (1.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-2)" 7.6 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.1 1.1 5.2 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.6 0.1 12.6 7.0 0.3 456.3 0.2 0.2 0.1 0.1 0.1 0.1 0.9 0.0 0.0 4.2 209.0 6.5 0.2 0.1 1.6 3.1 0.7 0.2 4.7 1.5 0.6 4.8 5.2 9.6 5.7 0.4 1.6 8.9 2.3 1.3 0.4 0.4 2.9 4.4 7.6 2.7 0.4 5.1 2.4 0.1 0.7 3.8 19.8 2.7 11.8 9.0 0.2 1.1 2.5 4.1 1.1 0.6 0.5 0.2 5.1 6.5 0.3 9.7 10.9 6.1 9.6 7.4 16.8 6.8 5.7 0.0 0.6 6.1 4.9 3.3 4.5 3.4 3.4 2.7 2.0 3.0 6.3 5.6 2.8 9.5 5.7 7.4 5.9 15.0 2.9 0.0 0.1 0.7 1.0 0.0 1.3 1.6 1.1 1.0 0.0 0.8 1.4 1.3 0.0 4.7 0.2 3.1 1.5 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 ATP2A2 "ATP2B, DAR, SERCA2" ENSG00000174437 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2" P16615 12 110280756-110351093 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 188.3;skeletal muscle: 319.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062605 Enhanced 38000000 "HPA062605: " "unprognostic (4.81e-2)" "unprognostic (2.16e-2)" "unprognostic (1.87e-1)" "unprognostic (3.41e-3)" "unprognostic (2.50e-1)" "unprognostic (3.98e-3)" "unprognostic (1.91e-2)" "unprognostic (6.20e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (1.36e-3)" "unprognostic (2.26e-1)" "unprognostic (5.62e-2)" "unprognostic (9.93e-2)" 8.4 8.8 7.3 8.5 14.5 5.7 7.5 7.4 20.8 8.2 9.6 8.0 8.3 7.3 9.4 10.3 24.1 9.4 9.3 188.3 10.1 5.0 6.7 11.8 8.9 5.6 5.6 13.1 8.5 7.6 8.7 6.1 8.1 10.2 13.0 11.2 22.3 18.3 9.6 319.7 9.3 9.3 14.3 7.4 5.4 7.9 11.9 7.1 3.1 12.6 51.3 12.7 13.4 11.4 0.8 2.2 0.2 4.4 1.7 1.7 0.7 34.9 69.8 35.4 28.4 23.5 30.2 51.0 43.7 55.0 44.3 29.9 50.5 37.3 43.2 37.0 41.5 51.2 58.5 69.0 50.4 35.7 29.3 37.7 28.0 29.5 40.0 43.0 36.5 31.7 48.6 56.3 54.6 34.2 43.9 21.2 36.0 33.6 23.2 26.7 40.3 35.3 24.6 31.8 35.7 21.8 72.3 37.4 28.1 54.9 45.2 25.5 60.7 23.2 36.7 41.1 22.1 27.3 33.3 43.6 53.0 48.5 37.4 18.6 46.5 0.0 1.9 0.0 1.7 4.4 0.9 0.7 1.3 1.1 1.9 0.8 1.3 1.2 0.2 1.7 2.3 2.2 1.2 0.7 7.3 14.5 7.4 20.8 10.1 5.0 5.6 13.1 10.2 7.1 ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 82.4;salivary gland: 88.1" "Cell line enhanced" "Detected in many" "Daudi: 39.1;HMC-1: 57.9;Karpas-707: 25.3;MOLT-4: 51.8;SK-BR-3: 42.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "cerebellum: 10.9;midbrain: 4.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in some" 15 "cerebellum: 75.4" "Low region specificity" "Detected in many" "HPA007180, CAB010882" Approved 100000000 "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (4.14e-2)" "prognostic favourable (4.69e-5)" "unprognostic (1.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.02e-2)" "prognostic favourable (2.51e-4)" "unprognostic (8.83e-3)" "unprognostic (2.30e-1)" "unprognostic (8.29e-2)" "unprognostic (3.67e-3)" "unprognostic (3.95e-3)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (1.60e-1)" "unprognostic (3.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-3)" 2.1 4.9 0.9 36.9 1.6 24.3 2.7 10.9 1.7 2.3 15.4 1.8 48.8 8.1 3.4 2.8 4.5 2.2 16.0 2.6 0.9 0.7 3.4 1.6 7.8 25.6 4.1 1.4 2.1 20.2 0.0 0.8 1.7 1.4 7.4 9.0 8.7 88.1 47.3 0.9 9.4 26.1 3.0 1.0 36.4 25.5 1.6 1.2 82.4 4.2 6.0 47.5 5.4 2.6 8.3 10.8 21.1 1.0 2.5 7.8 3.9 0.0 1.6 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.3 39.1 2.4 0.1 0.1 0.6 0.0 0.0 4.8 0.4 20.4 1.2 0.0 0.3 22.2 57.9 0.0 0.0 0.1 0.0 0.0 4.1 25.3 0.0 24.3 51.8 23.9 0.2 0.3 5.7 0.0 9.0 0.0 0.7 2.5 0.7 0.3 42.1 0.0 2.6 5.5 0.1 0.0 0.4 0.1 0.0 9.4 2.8 13.8 0.5 15.9 0.0 9.1 1.0 21.1 7.8 0.6 6.1 6.9 4.8 7.2 1.0 8.3 3.6 4.4 9.0 2.5 0.3 10.8 4.2 3.9 0.9 1.6 10.9 1.7 0.9 0.7 4.1 1.4 1.4 1.2 ATP2B1 PMCA1 ENSG00000070961 "ATPase plasma membrane Ca2+ transporting 1" P20020 12 89588049-89709300 "Enzymes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 53.8" "Cell line enhanced" "Detected in many" "hTERT-HME1: 58.4;LHCN-M2: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005605, HPA011166, HPA012945" Enhanced Supported "Plasma membrane" "Plasma membrane" "CAB005605: AB_2061563, HPA011166: AB_1855484, HPA012945: AB_1855483" "unprognostic (6.78e-2)" "unprognostic (5.27e-2)" "unprognostic (1.57e-2)" "unprognostic (8.23e-2)" "unprognostic (1.72e-1)" "unprognostic (6.44e-2)" "prognostic unfavourable (7.74e-4)" "unprognostic (2.77e-2)" "unprognostic (2.46e-2)" "unprognostic (7.82e-2)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (4.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" 8.7 5.1 23.4 12.5 53.8 40.5 8.8 30.9 44.1 9.0 14.0 4.1 4.0 17.8 8.2 5.8 6.5 8.4 11.3 5.2 29.0 11.8 7.4 10.0 9.2 11.8 7.8 31.5 7.6 7.4 13.7 8.7 11.7 9.2 6.4 14.8 2.9 5.6 6.9 10.9 11.3 12.8 8.7 6.1 12.7 12.4 9.8 16.4 5.7 6.3 6.0 12.3 9.9 7.4 27.1 16.2 41.5 25.6 8.4 16.3 6.2 4.1 21.1 8.3 4.0 12.1 19.3 3.8 12.8 41.9 12.4 19.8 8.4 3.9 8.2 0.9 17.7 3.7 7.3 3.5 34.7 2.8 8.5 2.9 7.4 7.4 39.5 12.2 4.9 15.9 6.7 38.6 58.4 3.1 4.8 3.0 90.7 6.6 3.8 5.2 6.5 10.1 5.4 26.8 3.4 11.8 19.3 7.9 4.3 14.8 4.2 3.5 6.1 1.4 2.2 33.7 5.5 12.3 13.9 2.3 3.5 8.8 15.3 3.5 7.4 2.7 13.0 6.7 7.1 13.6 9.0 27.1 12.4 9.0 16.2 27.0 4.6 5.7 41.5 8.4 25.6 2.9 16.3 6.2 23.4 53.8 30.9 44.1 29.0 11.8 7.8 31.5 9.2 16.4 ATP2B2 PMCA2 ENSG00000157087 "ATPase plasma membrane Ca2+ transporting 2" Q01814 3 10324023-10708007 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 55.1;liver: 15.2;salivary gland: 28.6;skeletal muscle: 30.3" "Group enriched" "Detected in some" 4 "EFO-21: 5.3;RPMI-8226: 15.0;SCLC-21H: 5.7" "Cancer enhanced" "Detected in some" "liver cancer: 7.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005606 Enhanced "CAB005606: AB_2243199" "unprognostic (2.04e-1)" "unprognostic (1.26e-2)" "unprognostic (6.84e-2)" "unprognostic (1.59e-2)" "unprognostic (3.59e-1)" "unprognostic (3.62e-1)" "unprognostic (4.09e-2)" "unprognostic (4.65e-1)" "unprognostic (5.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.32e-4)" "unprognostic (2.70e-1)" "unprognostic (1.46e-3)" "unprognostic (1.08e-3)" "unprognostic (1.33e-2)" "unprognostic (8.34e-2)" "unprognostic (7.95e-3)" 1.0 1.5 7.6 1.0 23.0 0.9 1.0 39.9 55.1 3.0 1.0 2.4 0.0 1.0 3.2 1.1 1.1 4.3 1.0 1.0 10.0 6.2 1.1 15.2 1.0 1.0 7.9 14.7 1.0 1.1 0.9 1.7 0.9 15.5 1.0 1.0 0.7 28.6 0.9 30.3 1.3 1.0 2.3 2.5 1.0 1.0 1.5 4.2 0.0 0.9 0.0 1.0 0.9 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 15.0 0.0 0.0 5.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 7.6 23.0 39.9 55.1 10.0 6.2 7.9 14.7 15.5 4.2 ATP2B3 "CFAP39, CLA2, PMCA3, SCAX1" ENSG00000067842 "ATPase plasma membrane Ca2+ transporting 3" Q16720 X 153517676-153582939 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Calmodulin-binding "Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 18.6;brain: 23.2" "Cell line enhanced" "Detected in some" "SCLC-21H: 14.3;SH-SY5Y: 4.2;THP-1: 3.5;U-937: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001583 Enhanced "HPA001583: AB_1079641" "unprognostic (1.35e-1)" "unprognostic (3.07e-2)" "unprognostic (3.28e-1)" "unprognostic (6.82e-2)" "unprognostic (1.30e-1)" "unprognostic (4.32e-2)" "unprognostic (2.67e-1)" "unprognostic (6.34e-2)" "unprognostic (2.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.38e-3)" "unprognostic (3.44e-1)" "unprognostic (2.71e-12)" "unprognostic (1.44e-3)" "unprognostic (2.04e-1)" "unprognostic (2.42e-2)" 0.8 18.6 5.4 0.9 11.3 0.8 0.8 16.1 23.2 0.8 0.9 3.9 0.0 0.9 0.9 2.6 0.8 3.1 0.8 0.8 7.8 5.5 1.0 0.8 0.8 0.8 4.3 11.5 0.8 0.9 0.8 1.2 1.7 13.6 0.8 0.8 1.4 1.3 1.3 0.8 0.9 0.9 0.9 1.4 0.8 0.8 1.1 0.9 0.0 0.8 0.0 0.8 0.8 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.3 4.2 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 11.3 16.1 20.7 7.8 5.5 4.3 11.5 13.6 0.9 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626561-203744081 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 42.6;BJ hTERT+: 60.6;fHDF/TERT166: 45.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" 21000 "Plasma membrane" "CAB016118: AB_2061729, HPA040431: " "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavourable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 23.0 14.0 24.8 10.8 14.2 5.9 11.6 9.4 23.6 32.6 44.2 7.5 12.9 5.3 69.6 13.1 20.4 27.0 13.9 24.0 13.1 8.7 5.0 14.2 16.1 5.3 6.4 19.2 21.9 6.4 8.0 4.8 16.2 9.3 17.0 13.4 11.6 7.5 31.5 5.4 22.0 13.2 74.2 5.7 4.8 16.4 13.1 7.5 9.0 8.3 8.4 7.7 32.8 14.2 1.0 4.2 4.5 2.2 4.2 10.4 2.6 9.3 1.7 3.4 3.2 26.5 39.5 18.3 42.6 60.6 7.3 6.2 0.8 4.8 2.1 6.2 45.9 9.2 5.0 5.9 7.6 27.0 1.8 6.3 8.5 0.5 9.5 9.0 11.2 28.7 5.8 23.2 3.6 13.8 2.7 4.3 5.3 0.5 9.1 3.0 2.1 5.3 4.7 2.6 3.4 2.4 0.8 1.0 1.5 15.0 2.2 6.8 2.0 4.4 12.1 17.6 2.6 29.5 10.2 2.9 4.2 1.2 17.6 6.5 5.2 3.0 2.2 0.0 10.4 1.5 7.9 1.0 6.6 8.3 2.4 0.3 1.6 4.2 4.5 4.2 2.2 4.2 6.3 2.6 24.8 14.2 9.4 23.6 13.1 8.7 6.4 19.2 9.3 7.5 ATP2C1 "ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1" ENSG00000017260 "ATPase secretory pathway Ca2+ transporting 1" P98194 3 130850595-131016712 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010207, HPA035116, HPA069684" Supported Supported "Golgi apparatus" 28000 "Golgi apparatus" "CAB010207: AB_2061744, HPA035116: AB_10673106, HPA069684: " "unprognostic (1.52e-1)" "unprognostic (1.37e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "prognostic unfavourable (5.06e-6)" "unprognostic (7.66e-2)" "unprognostic (6.52e-2)" "unprognostic (2.45e-1)" "prognostic unfavourable (1.52e-4)" "unprognostic (8.44e-2)" "prognostic favourable (1.55e-4)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "unprognostic (3.06e-1)" 18.6 22.9 29.6 14.5 29.4 20.4 36.8 24.5 34.6 22.2 21.6 23.0 14.3 14.4 19.3 18.0 16.9 23.4 16.8 19.2 31.6 32.3 28.0 17.1 30.7 16.0 31.8 25.4 18.5 14.6 47.6 31.0 19.6 26.7 54.0 22.4 18.1 20.3 16.6 16.1 21.3 16.0 19.2 44.6 11.1 18.7 16.0 25.6 20.5 21.7 15.5 15.4 19.3 29.6 4.7 7.6 21.6 7.0 8.7 7.2 4.9 36.2 14.2 14.3 13.8 40.0 32.5 15.4 39.6 52.8 19.9 25.2 23.1 29.9 13.1 27.5 37.4 43.2 26.8 21.8 29.2 28.4 9.6 35.0 15.1 10.7 25.6 13.9 42.7 25.4 22.0 20.9 23.8 21.1 10.0 23.9 24.5 16.1 13.6 11.1 16.2 15.5 9.9 14.3 20.7 36.7 24.4 22.1 13.2 34.0 10.6 19.9 15.8 11.5 28.7 21.2 11.9 27.3 18.2 15.5 18.8 19.5 21.9 10.5 17.7 21.6 7.0 12.1 6.3 6.0 5.9 4.7 6.2 5.6 7.6 2.9 4.3 4.3 3.5 8.7 7.0 6.6 7.2 4.9 29.6 29.4 24.5 34.6 31.6 32.3 31.8 25.4 26.7 25.6 ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.0;salivary gland: 35.8" "Cell line enhanced" "Detected in some" "HaCaT: 6.3;MCF7: 16.3;RT4: 12.9;SK-BR-3: 22.7;T-47d: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 24 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 24 "granulocytes: 2.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" "Plasma membrane, Focal adhesion sites" "HPA052262: , HPA075812: " "unprognostic (2.28e-2)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "prognostic favourable (6.20e-6)" "unprognostic (2.04e-1)" "unprognostic (2.41e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.92e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.16e-1)" "unprognostic (8.37e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-4)" "unprognostic (1.39e-1)" 0.3 0.0 2.1 8.0 1.5 6.1 2.5 0.2 2.0 3.5 23.0 0.5 1.9 16.3 1.8 1.9 2.7 4.0 18.8 0.4 1.8 1.9 2.6 0.2 21.9 0.2 1.3 0.7 1.3 0.5 0.0 2.9 4.8 0.7 7.9 21.9 1.0 35.8 0.2 0.9 15.2 14.5 0.5 0.6 0.2 3.4 0.4 0.4 0.3 8.2 2.2 8.1 4.8 7.8 0.0 0.0 2.7 0.0 0.0 0.1 0.0 4.1 0.3 0.5 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.0 3.9 3.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 12.9 3.3 0.0 0.0 22.7 0.2 7.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 2.1 1.5 0.2 2.0 1.8 1.9 1.3 0.7 0.7 0.4 ATP4A ATP6A ENSG00000105675 "ATPase H+/K+ transporting alpha subunit" P20648 19 35550043-35563658 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "stomach 1: 120.1" "Cell line enhanced" "Detected in some" "THP-1: 1.1;U-138 MG: 1.5" "Cancer enriched" "Detected in single" 21 "stomach cancer: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA039154 Enhanced 790000 "HPA039154: AB_10672772" "unprognostic (3.54e-2)" "unprognostic (6.98e-3)" "unprognostic (2.77e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-1)" "unprognostic (9.68e-2)" "unprognostic (1.47e-3)" "unprognostic (3.90e-3)" "unprognostic (3.92e-2)" "unprognostic (4.86e-2)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" 0.1 0.2 0.1 0.1 0.6 0.0 0.1 0.1 0.6 0.1 0.1 3.4 0.1 0.0 0.1 0.1 4.9 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 2.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 2.1 0.1 0.1 120.1 0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.1 0.0 1.5 0.3 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.1 ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56646068 "Enzymes, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria 100000000 Mitochondria "CAB017527: AB_1121153, HPA001520: AB_1078243, HPA001528: AB_1078242" "prognostic unfavourable (7.17e-6)" "unprognostic (5.69e-2)" "unprognostic (1.08e-2)" "unprognostic (7.24e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.92e-2)" "unprognostic (8.19e-3)" "unprognostic (2.38e-2)" "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "prognostic favourable (1.43e-9)" "unprognostic (2.79e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.30e-2)" 41.3 66.2 32.4 34.1 53.4 39.3 33.1 55.4 92.6 26.1 73.0 34.4 36.1 68.1 27.9 28.5 58.6 28.5 36.9 225.0 33.2 34.9 95.2 85.7 28.3 39.2 40.5 35.5 25.1 42.7 85.2 30.1 31.3 69.6 29.0 78.5 42.8 64.7 38.1 236.2 42.3 74.6 35.5 24.9 33.5 51.0 31.4 18.3 47.5 38.4 123.6 45.8 36.6 32.8 41.2 91.7 40.2 90.1 36.3 46.6 105.6 65.7 80.0 63.6 98.1 57.4 61.4 112.4 66.9 62.5 115.7 65.9 129.9 73.4 117.0 72.5 82.4 88.2 134.0 81.1 104.8 54.8 92.8 128.3 74.7 79.6 71.1 143.5 90.9 75.2 81.9 90.4 116.8 95.0 115.5 134.9 97.0 61.0 106.3 84.4 107.0 154.1 102.4 71.2 149.1 126.0 117.2 72.8 64.7 102.2 146.4 113.7 137.4 108.5 64.4 45.6 50.8 66.5 72.2 65.1 80.9 121.0 68.6 96.0 69.8 40.2 64.6 34.6 40.2 80.6 44.9 41.2 38.0 42.7 91.7 31.7 31.1 36.7 17.8 36.3 90.1 46.3 46.6 105.6 32.4 53.4 55.4 92.6 33.2 34.9 40.5 35.5 69.6 18.3 ATP6V1A "ATP6A1, ATP6V1A1, VA68, Vma1, VPP2" ENSG00000114573 "ATPase H+ transporting V1 subunit A" P38606 3 113747019-113812056 "Disease related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.6" "Group enriched" "Detected in all" 6 "dendritic cells: 16.4;granulocytes: 33.6;monocytes: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006910, HPA035083, HPA035084" Approved Supported Nucleoplasm,Vesicles,Cytosol 2700000 "Nucleoplasm, Vesicles" Cytosol "CAB006910: , HPA035083: AB_2674453, HPA035084: AB_2674454" "unprognostic (1.32e-1)" "unprognostic (8.68e-2)" "unprognostic (5.87e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.00e-1)" "unprognostic (3.43e-2)" "unprognostic (2.90e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-2)" "unprognostic (5.19e-3)" "prognostic favourable (3.82e-12)" "unprognostic (8.82e-2)" "unprognostic (2.46e-3)" "unprognostic (2.43e-1)" "unprognostic (1.52e-2)" 12.8 19.8 24.1 10.4 33.2 7.4 12.7 34.8 52.8 14.0 11.1 10.3 5.6 9.3 7.5 8.2 13.2 10.0 10.8 4.7 26.2 38.2 47.9 18.2 12.3 11.4 25.4 25.0 6.2 10.5 39.3 13.5 12.3 52.0 11.2 11.8 14.7 18.0 8.4 4.5 12.6 7.9 8.2 13.6 13.7 10.9 8.9 8.3 9.6 21.0 5.7 13.6 10.2 8.2 3.8 16.4 33.6 15.4 3.8 3.4 6.0 25.0 11.4 14.4 12.5 30.3 13.6 15.3 13.6 20.8 14.3 19.8 21.5 20.2 20.5 32.3 19.8 16.3 32.4 17.9 18.8 9.3 8.9 18.2 17.7 16.5 25.1 13.3 21.3 18.3 12.4 18.5 12.9 23.2 20.8 15.6 21.2 16.4 9.7 6.0 18.0 14.3 8.4 10.4 23.3 39.1 23.9 27.9 10.3 23.8 16.2 17.8 24.6 10.8 21.3 13.3 10.0 9.1 8.1 16.3 17.5 19.0 26.2 16.9 14.8 9.2 15.4 5.2 2.8 11.7 2.6 3.8 2.6 2.7 16.4 2.9 2.5 2.9 33.6 3.8 9.5 4.6 3.4 6.0 24.1 33.2 34.8 52.8 26.2 38.2 25.4 25.0 52.0 8.3 ATP7A MNK ENSG00000165240 "ATPase copper transporting alpha" Q04656 X 77910656-78050395 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012887, HPA048107" Approved Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA012887: AB_1845205, HPA048107: " "unprognostic (3.14e-2)" "unprognostic (3.48e-1)" "unprognostic (4.90e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-3)" "unprognostic (2.59e-2)" "unprognostic (3.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.30e-2)" "unprognostic (1.14e-1)" "prognostic favourable (8.38e-4)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (3.69e-1)" "unprognostic (2.52e-1)" 9.8 7.4 2.6 8.6 4.6 6.4 8.5 2.3 2.9 8.2 7.7 5.9 9.6 4.8 9.5 7.6 10.0 5.7 4.5 5.1 2.9 2.8 9.0 3.3 9.3 9.3 4.1 1.7 7.3 6.3 13.2 15.9 5.0 4.3 8.2 4.4 5.2 12.3 10.3 6.1 15.9 8.5 7.8 6.3 10.8 7.0 2.7 6.0 15.6 6.0 7.1 11.7 11.8 7.0 2.3 1.4 10.7 2.4 1.7 3.0 1.2 2.5 6.7 4.5 4.6 4.3 4.5 0.8 3.9 5.4 2.3 4.8 0.9 3.0 3.7 5.8 3.8 3.1 5.8 3.1 4.4 5.5 4.0 1.9 6.5 0.7 5.4 3.3 3.5 4.8 1.3 5.0 1.5 6.1 15.3 14.4 4.3 2.2 3.5 1.1 1.3 1.4 2.9 7.5 12.6 3.9 7.2 1.4 17.1 9.6 2.4 4.9 1.8 1.1 7.7 3.1 3.1 4.3 1.5 4.7 8.3 4.3 5.1 2.0 4.7 8.3 2.0 5.5 2.4 1.9 1.2 2.0 1.7 1.7 1.3 2.3 2.1 3.0 10.7 1.7 2.4 1.4 0.6 1.2 2.6 4.6 2.3 2.9 2.9 2.8 4.1 1.7 4.3 6.0 ATP7B WND ENSG00000123191 "ATPase copper transporting beta" P35670 13 51930436-52012125 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 18.5;liver: 13.5" "Cell line enhanced" "Detected in many" "BEWO: 18.8;CACO-2: 10.8;HEL: 28.6;Hep G2: 9.9;RPTEC TERT1: 16.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA009137, HPA013187" Supported Supported "Golgi apparatus" "Golgi apparatus" "HPA009137: , HPA013187: AB_1845206" "unprognostic (1.13e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "prognostic unfavourable (5.01e-4)" "unprognostic (3.49e-1)" "unprognostic (5.51e-2)" "unprognostic (1.55e-2)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (5.77e-2)" "unprognostic (8.29e-2)" "unprognostic (1.17e-1)" "unprognostic (3.26e-3)" "unprognostic (4.66e-2)" "unprognostic (3.54e-1)" "unprognostic (6.21e-3)" "unprognostic (1.40e-1)" 3.4 0.7 1.8 2.4 2.9 1.8 1.6 7.0 2.8 1.4 6.8 1.1 1.1 10.5 1.6 1.9 1.1 1.9 18.5 1.8 2.1 2.1 2.1 13.5 1.2 1.1 1.6 1.1 2.0 1.7 7.7 1.2 7.1 3.5 1.9 2.6 1.4 3.0 1.1 1.1 0.7 9.6 1.5 1.1 1.6 4.5 7.1 1.6 1.1 1.1 1.1 1.1 2.1 1.1 0.0 0.0 1.0 0.3 0.0 0.5 0.1 0.4 1.6 2.9 2.6 0.6 0.5 18.8 0.8 0.2 0.9 0.6 10.8 0.1 0.0 0.3 1.4 0.2 2.0 2.4 0.6 0.2 4.0 28.6 0.3 9.9 0.9 0.3 6.7 1.2 2.8 0.1 1.1 2.0 7.6 0.0 0.8 0.5 0.1 0.7 0.9 0.9 1.0 0.8 0.0 16.7 1.8 2.2 1.2 1.0 1.6 1.1 4.5 0.2 1.1 0.1 1.0 1.6 0.3 0.3 0.4 0.1 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 1.8 2.9 7.0 2.8 2.1 2.1 1.6 1.1 3.5 1.6 ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657105 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 38.9" "Cell line enhanced" "Detected in many" "AN3-CA: 16.8;Daudi: 27.6;HEL: 9.7;REH: 9.5;SH-SY5Y: 9.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Supported Vesicles 20000 Vesicles "HPA052935: " "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favourable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" 5.3 8.6 14.2 8.0 29.6 18.5 4.8 7.2 32.0 3.1 11.3 27.3 8.4 4.2 3.4 11.6 2.9 3.5 2.8 8.0 13.7 8.8 4.0 2.1 10.6 12.5 18.0 17.4 15.1 10.0 38.9 6.9 2.6 15.3 7.9 10.7 3.9 4.4 15.2 16.9 3.2 8.1 3.1 23.1 7.8 10.5 2.8 24.9 8.9 34.9 1.9 10.3 4.5 4.0 4.4 3.8 0.9 3.3 3.2 7.3 0.9 0.0 0.1 0.2 16.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.2 27.6 7.8 0.1 1.4 4.0 0.0 0.0 4.4 2.7 9.7 0.9 0.4 0.0 2.3 0.2 0.3 0.0 0.0 0.0 0.1 0.0 3.1 0.0 1.2 3.5 0.8 1.2 0.3 9.5 0.0 3.1 6.0 0.3 3.0 9.2 0.2 5.8 0.0 1.9 0.0 0.2 0.0 1.3 0.3 0.0 1.1 0.0 5.6 0.4 3.3 0.1 0.0 1.0 0.9 6.0 0.4 3.2 2.6 1.9 6.5 0.9 4.4 2.9 7.3 0.9 3.2 3.3 3.8 1.4 0.9 14.2 29.6 7.2 22.1 13.7 8.8 18.0 17.4 15.3 24.9 ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25372071-26025851 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 34.9;pituitary gland: 37.0;testis: 10.4" "Cell line enriched" "Detected in some" 6 "HMC-1: 21.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.3;naive CD8 T-cell: 3.3" "Lineage enriched" "Detected in single" 12 "T-cells: 3.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: " "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" 1.1 4.9 11.2 1.4 11.4 0.8 2.2 34.9 30.2 1.1 1.3 1.3 0.0 1.4 2.1 4.8 0.9 0.9 1.0 1.0 9.4 11.8 1.3 0.8 2.3 1.9 6.7 10.4 1.2 1.9 0.9 37.0 1.2 19.8 1.1 1.3 3.1 1.0 1.0 1.3 0.9 1.5 1.0 3.5 1.3 1.8 10.4 1.4 0.0 1.0 0.0 1.2 1.2 0.3 0.0 0.0 0.2 0.0 0.2 3.3 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 1.0 0.0 0.6 1.4 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 21.9 0.2 0.0 0.0 0.0 0.5 0.0 0.0 1.7 0.3 3.7 0.0 2.0 0.7 0.0 2.7 1.0 0.2 0.1 3.3 0.0 0.2 0.3 0.1 0.0 0.4 0.2 0.1 1.1 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.8 0.6 0.0 0.0 2.3 3.3 0.2 0.2 0.0 0.0 0.7 0.6 11.2 11.4 34.9 18.4 9.4 11.8 6.7 10.4 19.8 1.4 ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803101 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" "Disease mutation, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 27.1;HBF TERT88: 24.3;RT4: 57.5" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA018673, HPA018674" Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" "Plasma membrane" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favourable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favourable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" 3.8 2.3 0.0 1.8 0.0 0.0 3.4 0.0 0.3 4.5 21.3 8.9 2.4 0.8 6.7 2.6 4.8 1.8 0.2 0.0 2.1 3.0 3.6 0.0 0.1 0.7 10.7 2.7 1.1 1.3 6.0 19.3 5.8 2.8 0.4 3.6 11.1 2.0 0.2 1.2 13.3 0.0 5.7 0.2 12.8 5.4 6.0 2.0 4.7 2.1 0.7 1.3 0.3 10.1 3.4 0.1 0.1 3.5 6.4 4.9 19.6 19.1 20.6 12.9 2.6 8.8 0.7 5.9 27.1 15.0 0.1 4.1 24.3 0.2 0.4 0.1 0.9 0.9 1.1 0.2 0.1 1.0 3.7 6.2 10.9 10.8 0.1 0.4 11.9 4.8 0.2 0.2 0.2 1.0 0.1 0.1 0.2 2.8 57.5 0.4 0.3 0.4 12.1 0.1 3.7 0.6 12.4 16.8 0.6 2.7 4.5 0.2 0.1 0.2 0.4 0.2 0.9 0.8 2.1 0.5 1.3 0.9 1.0 2.7 1.0 0.7 0.5 6.0 0.9 1.0 4.7 0.7 1.2 2.0 0.4 0.3 ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325553-154351307 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 3.1;T-cells: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046680 Approved "HPA046680: " "unprognostic (1.68e-1)" "unprognostic (3.68e-1)" "unprognostic (8.40e-2)" "unprognostic (5.16e-2)" "unprognostic (4.52e-1)" "unprognostic (8.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.69e-1)" "prognostic favourable (1.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.89e-3)" "unprognostic (7.77e-3)" "unprognostic (6.58e-2)" "unprognostic (3.19e-2)" "prognostic unfavourable (5.29e-5)" 13.6 7.0 5.5 15.0 7.1 3.4 11.9 26.8 8.9 29.1 11.2 7.4 11.5 8.6 28.9 15.2 14.4 21.5 18.4 11.7 7.0 6.8 6.6 2.6 12.2 16.1 6.2 5.8 27.5 5.3 5.1 13.9 10.9 6.1 15.3 6.8 12.5 5.4 16.4 4.3 6.1 11.8 29.4 5.1 14.7 11.4 12.7 5.1 18.9 11.2 8.1 13.6 20.5 24.9 0.6 0.7 3.1 0.0 0.9 6.5 1.0 0.7 5.0 6.4 6.6 41.0 27.8 0.1 15.4 25.7 8.9 10.7 0.1 0.2 0.6 8.2 37.1 3.1 7.6 1.8 6.2 16.9 6.2 6.4 6.2 5.8 12.5 0.0 5.0 17.9 0.4 13.6 13.0 13.7 12.7 15.5 7.6 6.6 12.0 0.7 15.2 6.4 13.4 4.4 22.9 1.7 0.1 5.7 7.9 4.0 0.8 9.6 4.7 4.8 12.0 13.6 6.8 17.0 4.6 21.5 26.3 3.8 4.7 0.7 8.2 3.1 0.0 3.0 2.2 0.0 1.5 0.6 3.5 3.7 0.0 0.4 2.9 2.5 0.1 0.9 0.0 0.7 6.5 1.0 5.5 7.1 26.8 8.9 7.0 6.8 6.2 5.8 6.1 5.1 ATP8B4 "ATPIM, KIAA1939" ENSG00000104043 "ATPase phospholipid transporting 8B4 (putative)" Q8TF62 15 49858238-50182817 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.1;cervix, uterine: 26.0;endometrium 1: 18.2" "Cell line enhanced" "Detected in some" "HMC-1: 18.6;NB-4: 7.1;THP-1: 12.0;U-937: 37.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 6.9;NK-cell: 10.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040254 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA040254: AB_10673028" "unprognostic (6.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.39e-2)" "unprognostic (2.96e-3)" "unprognostic (3.25e-1)" "unprognostic (6.51e-3)" "unprognostic (1.03e-1)" "unprognostic (4.87e-3)" "unprognostic (1.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.20e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" 2.3 1.2 1.6 1.5 2.1 28.1 1.0 0.6 0.9 26.0 1.5 1.7 1.6 0.4 18.2 3.5 0.6 9.5 3.1 0.8 2.5 0.9 1.0 1.2 3.2 0.7 2.7 0.1 3.9 0.4 0.2 1.1 2.9 2.1 0.7 1.2 0.8 0.9 0.6 0.4 0.5 1.1 2.7 3.1 2.3 0.6 0.9 4.6 0.8 0.5 0.8 2.1 1.3 1.5 0.0 2.2 6.9 1.7 10.6 0.5 0.8 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.1 0.0 3.0 0.6 0.0 0.0 5.2 18.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 12.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.4 37.6 0.0 6.9 1.7 2.4 0.5 0.8 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.8 10.6 0.3 0.0 0.0 0.8 1.6 2.1 0.6 0.9 2.5 0.9 2.7 0.1 2.1 4.6 ATP9A "ATPIIA, KIAA0611" ENSG00000054793 "ATPase phospholipid transporting 9A (putative)" O75110 20 51596514-51768634 "Enzymes, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 64.7" "Cell line enhanced" "Detected in many" "EFO-21: 28.8;SK-BR-3: 27.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 6.3;NK-cell: 2.2" "Group enriched" "Detected in many" 5 "granulocytes: 6.3;NK-cells: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020699, HPA035630" Enhanced "CAB020699: , HPA035630: AB_10669526" "unprognostic (5.19e-2)" "unprognostic (5.28e-2)" "unprognostic (3.46e-1)" "unprognostic (1.05e-1)" "unprognostic (3.76e-1)" "unprognostic (1.37e-1)" "unprognostic (3.76e-2)" "unprognostic (4.79e-2)" "unprognostic (7.45e-2)" "unprognostic (1.58e-1)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "prognostic favourable (5.67e-5)" "unprognostic (5.82e-2)" "unprognostic (5.81e-1)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" 18.5 8.2 23.7 3.9 31.8 2.0 11.2 29.8 64.7 5.6 12.2 19.9 8.2 9.1 8.6 13.1 8.8 16.9 8.2 7.7 24.3 26.8 6.8 5.4 6.7 2.6 21.1 23.9 13.2 10.0 22.7 8.3 3.6 22.5 14.3 11.3 4.1 14.9 11.3 9.2 4.1 11.5 8.7 18.9 2.2 14.0 12.4 15.8 0.8 18.7 2.9 2.4 7.4 5.6 0.0 0.0 6.3 0.2 2.2 0.8 1.8 9.5 8.2 6.7 15.1 19.9 14.9 0.1 3.4 6.6 2.2 0.7 18.8 19.9 0.0 28.8 14.2 7.7 8.9 5.0 2.3 7.4 2.7 0.0 9.1 7.5 2.7 0.0 0.0 4.9 10.2 0.5 1.4 12.2 0.0 0.0 2.6 13.4 0.7 0.0 1.2 10.4 1.5 0.0 0.0 4.6 13.5 12.8 9.1 13.8 27.6 5.1 5.2 0.2 8.0 19.0 5.1 7.4 1.4 0.0 0.1 0.3 5.0 0.0 1.7 6.3 0.0 0.0 0.8 0.2 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.4 2.2 0.1 0.0 0.0 1.8 23.7 31.8 29.8 34.9 24.3 26.8 21.1 23.9 22.5 15.8 ATP9B ATPIIB ENSG00000166377 "ATPase phospholipid transporting 9B (putative)" O43861 18 79069285-79378287 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029364 Approved "HPA029364: AB_10602595" "unprognostic (2.84e-3)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (6.51e-3)" "unprognostic (7.32e-2)" "unprognostic (7.66e-4)" "unprognostic (2.45e-2)" "unprognostic (7.43e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (1.61e-1)" "unprognostic (2.93e-1)" "unprognostic (1.92e-3)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.05e-2)" "unprognostic (1.09e-2)" 14.5 11.0 11.7 16.8 11.6 30.1 11.7 16.8 15.2 14.3 10.7 17.5 15.2 7.1 21.8 17.6 11.3 11.9 14.5 10.7 11.4 8.2 13.1 16.7 13.9 13.2 10.8 9.7 18.2 14.3 25.8 15.5 10.9 11.3 12.8 11.4 12.3 14.2 17.3 18.8 13.3 9.1 14.8 17.1 9.7 11.5 22.1 12.4 19.3 14.6 9.6 16.4 14.6 13.3 9.8 8.4 14.2 16.3 8.6 12.2 6.9 15.4 8.1 11.3 12.5 5.9 9.9 8.8 8.3 5.6 5.0 4.2 8.7 11.0 8.6 13.9 6.0 7.0 9.3 4.6 8.1 13.2 3.9 10.1 9.3 6.1 7.8 18.4 10.9 7.9 5.9 8.1 5.0 6.9 9.7 21.8 7.0 13.5 12.0 7.2 16.1 10.1 11.5 9.4 11.5 7.1 13.4 8.4 8.8 9.3 9.8 5.7 11.5 11.0 12.1 10.5 17.1 4.7 5.5 10.9 17.8 19.4 6.1 12.2 10.8 14.2 12.0 9.1 8.4 10.1 9.8 9.0 9.6 8.1 8.4 9.8 12.2 9.5 13.0 8.6 16.3 8.0 7.4 6.9 11.7 11.6 16.8 15.2 11.4 8.2 10.8 9.7 11.3 12.4 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449235-142578826 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA054320: " "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavourable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavourable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 10.5 24.3 7.7 11.4 15.9 10.1 14.8 11.3 14.6 10.1 8.5 10.0 10.4 6.0 14.7 16.8 9.4 12.1 9.3 8.8 9.8 7.1 9.6 12.0 10.3 16.0 10.0 8.1 12.3 13.6 18.0 22.5 8.8 12.5 11.0 11.2 9.5 12.5 10.8 7.7 11.2 10.9 9.8 8.8 14.2 9.0 15.3 9.7 19.0 13.8 7.7 15.1 10.9 10.6 5.8 2.8 2.2 4.0 6.7 6.0 0.8 22.5 11.1 7.4 8.4 10.6 11.6 8.8 12.4 7.0 9.3 9.6 5.2 7.2 18.4 12.9 8.8 14.6 10.9 11.5 14.1 5.9 7.2 10.1 8.4 5.0 4.7 16.9 5.7 9.1 6.4 8.8 10.5 9.6 7.0 8.3 9.5 9.9 12.7 7.0 7.1 7.9 10.6 10.8 13.3 9.4 10.5 5.3 5.3 22.9 8.3 8.1 12.1 6.9 12.4 9.5 4.8 12.3 13.3 10.8 6.4 17.1 12.3 6.6 7.5 0.7 2.7 2.2 4.4 4.0 6.0 3.1 3.2 4.2 2.8 5.8 4.1 4.0 1.7 6.7 2.5 2.5 2.4 0.8 7.7 15.9 11.3 14.6 9.8 7.1 10.0 8.1 12.5 9.7 ATRX "JMS, MRX52, RAD54, XH2, XNP" ENSG00000085224 "ATRX, chromatin remodeler" P46100 X 77504878-77786269 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001906, CAB009372, HPA064684, CAB068176" Supported Supported "Nuclear bodies" "Nuclear bodies" "CAB009372: AB_2061023, CAB068176: , HPA001906: AB_1078249, HPA064684: " "unprognostic (1.77e-2)" "unprognostic (1.55e-1)" "unprognostic (6.65e-2)" "unprognostic (4.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.15e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (5.80e-2)" "unprognostic (5.14e-3)" "unprognostic (1.50e-1)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-1)" 16.4 16.6 24.5 18.9 29.3 24.3 16.3 48.2 26.4 20.6 15.4 7.1 18.9 10.2 20.2 17.1 13.5 13.8 13.4 15.1 22.9 15.8 16.6 12.2 15.9 18.6 21.1 21.3 25.4 18.3 35.7 28.1 15.9 20.2 18.4 12.6 7.1 15.8 16.5 20.1 14.1 13.5 22.3 15.3 20.1 15.6 6.5 22.4 23.7 19.8 12.7 16.5 19.9 21.1 21.9 12.8 21.5 11.5 14.6 17.7 5.7 15.1 24.4 25.1 16.8 12.5 16.8 8.9 13.1 12.1 9.7 11.5 8.3 13.3 21.0 13.5 13.9 13.5 20.0 7.8 16.6 11.8 13.1 12.7 29.0 6.1 6.8 16.5 4.4 11.1 7.7 14.3 13.7 17.1 14.9 24.2 12.1 11.9 12.7 8.6 18.1 18.9 20.6 34.6 10.8 9.5 20.3 14.3 24.7 26.4 10.4 8.7 8.3 8.4 23.6 13.7 21.3 15.4 9.2 7.2 22.3 18.9 10.1 13.1 12.1 21.3 6.9 13.8 17.7 8.7 17.1 19.2 16.3 13.7 5.1 21.9 16.8 13.5 21.5 14.6 11.5 12.8 12.8 5.7 24.5 29.3 48.2 26.4 22.9 15.8 21.1 21.3 20.2 22.4 ATXN3 "ATX3, JOS, MJD, SCA3" ENSG00000066427 "Ataxin 3" P54252 14 92044496-92106625 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB021976, HPA024123, HPA069338" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB021976: , HPA024123: AB_1845133, HPA069338: " "unprognostic (1.06e-2)" "unprognostic (2.93e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-2)" "unprognostic (5.76e-2)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (9.85e-3)" "unprognostic (1.69e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-2)" "unprognostic (3.06e-2)" "unprognostic (2.03e-2)" "unprognostic (8.94e-3)" "unprognostic (4.22e-1)" "unprognostic (1.64e-1)" "unprognostic (1.11e-1)" 17.8 10.3 10.2 9.1 11.6 14.3 12.8 18.7 12.1 16.0 11.8 12.2 11.9 6.4 17.9 12.4 17.7 9.5 11.2 10.4 9.0 9.9 9.9 16.0 12.3 11.6 16.3 9.5 14.0 10.3 11.9 17.2 11.7 13.8 15.8 11.7 8.6 11.4 10.2 6.1 21.0 8.7 20.6 16.5 12.6 9.0 14.8 14.3 16.2 11.5 12.0 15.6 15.4 13.6 9.8 14.5 11.4 18.8 7.0 8.5 5.3 5.6 11.1 10.0 9.3 14.6 14.3 19.6 6.4 10.4 8.2 11.4 8.0 15.7 11.5 12.8 10.5 9.8 7.7 14.0 18.1 13.1 2.3 4.9 5.4 11.7 12.1 8.6 8.8 11.6 12.5 14.3 15.0 12.6 6.5 8.6 12.4 21.9 9.0 7.8 7.1 9.2 7.2 18.5 6.5 10.5 12.8 3.4 6.0 15.5 6.6 8.8 12.3 6.0 6.7 8.1 11.9 5.2 3.4 7.5 12.5 10.6 6.0 8.5 4.7 11.4 13.4 9.4 5.9 14.5 7.0 7.1 6.9 6.5 14.5 9.8 7.6 8.5 11.3 7.0 18.8 8.4 6.8 5.3 10.2 11.6 18.7 12.1 9.0 9.9 16.3 9.5 13.8 14.3 ATXN3L MJDL ENSG00000123594 "Ataxin 3 like" Q9H3M9 X 13318236-13320399 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024123, HPA027539" Uncertain "HPA024123: AB_1845133, HPA027539: AB_10602435" 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361913 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favourable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" 13.0 39.6 14.3 15.6 20.1 3.8 15.2 22.5 20.7 14.1 19.8 10.5 25.3 19.2 11.1 16.0 8.9 10.7 11.4 30.4 15.4 19.7 50.4 21.3 9.7 6.7 19.1 9.0 11.8 20.7 27.0 10.1 13.1 16.3 23.8 14.4 10.6 20.1 35.4 31.0 6.7 16.0 10.4 15.2 7.7 17.7 6.1 12.1 9.1 17.5 11.8 8.9 10.2 10.5 8.7 5.8 16.1 4.6 9.9 10.0 5.3 4.5 4.4 6.3 3.2 7.8 8.4 9.7 4.1 5.2 3.2 3.7 2.5 5.9 5.4 4.3 4.3 6.7 9.3 5.2 4.6 41.3 7.9 3.6 4.9 14.8 5.9 5.3 3.8 7.0 6.6 2.6 8.9 3.9 5.1 8.1 3.7 4.4 7.2 11.9 7.8 6.5 4.3 5.0 9.2 14.0 2.4 6.4 4.6 6.1 14.7 7.7 2.7 3.5 4.0 3.2 4.0 4.7 3.9 9.3 7.8 1.8 5.1 4.3 2.1 15.2 4.6 16.1 6.9 3.2 7.9 7.8 7.6 10.0 4.2 8.7 9.6 8.8 7.1 9.9 2.1 5.8 9.3 5.3 14.3 20.1 22.5 20.7 15.4 19.7 19.1 9.0 16.3 12.1 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 32.3;testis: 41.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Centrosome, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavourable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavourable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavourable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 3.7 2.3 1.5 12.7 1.3 8.3 3.0 1.3 1.8 1.4 6.7 1.3 0.8 7.3 1.8 1.2 7.7 1.1 3.7 4.1 1.1 1.1 2.4 5.1 2.9 12.3 1.6 0.9 8.3 1.4 0.3 0.7 6.1 1.5 1.0 8.3 1.5 2.7 0.5 6.9 2.1 7.2 2.7 1.3 7.4 4.3 41.1 1.1 32.3 1.2 5.9 13.3 2.4 2.4 3.9 5.2 6.0 8.7 2.0 6.6 2.6 32.5 24.0 16.1 11.3 0.9 2.1 20.4 26.7 12.5 64.7 27.3 67.2 22.8 10.7 18.4 10.9 26.3 28.5 17.9 69.0 9.6 10.9 19.0 24.6 41.8 0.5 25.4 26.8 1.0 1.9 22.4 20.1 15.1 21.5 8.5 27.5 33.2 15.2 19.7 14.7 24.8 11.6 31.1 11.8 10.3 8.6 13.9 7.5 37.3 43.0 17.9 25.5 15.9 8.6 28.1 27.9 15.5 37.6 11.9 13.8 18.5 15.2 14.8 23.2 0.2 5.3 6.0 1.9 8.7 2.9 3.9 3.3 1.9 5.2 1.4 1.5 1.5 3.7 2.0 4.8 1.2 6.6 2.6 1.5 1.3 1.3 1.8 1.1 1.1 1.6 0.9 1.5 1.1 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;lymphoid tissue: 59.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.9" "Lineage enriched" "Detected in many" 5 "T-cells: 10.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Supported Nucleoplasm,Midbody "Nucleoplasm, Midbody" "CAB005862: AB_449204, HPA037708: " "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavourable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.2 1.3 0.4 22.1 0.6 19.7 2.0 0.6 0.6 2.6 5.8 0.5 0.9 5.9 0.9 1.3 17.1 0.3 2.2 1.0 0.4 0.2 1.4 1.8 2.4 17.8 0.4 0.4 0.8 0.6 0.0 0.4 3.8 0.8 0.9 5.5 0.7 2.7 0.4 2.1 5.0 8.1 1.3 0.7 11.2 4.2 1.2 0.4 59.9 0.5 8.0 19.1 2.1 5.0 2.3 0.8 1.2 0.6 0.5 10.9 1.4 41.0 28.2 42.0 20.2 0.9 1.4 16.1 19.7 10.6 40.8 37.7 36.5 12.4 41.0 10.2 7.8 30.2 30.5 13.5 33.8 18.0 50.1 24.4 16.1 30.8 0.1 12.9 24.0 0.7 0.6 23.9 15.0 18.8 15.2 15.9 17.9 19.5 46.8 18.3 26.1 12.6 31.7 38.7 17.0 8.9 8.1 9.1 13.0 17.5 7.9 13.4 13.8 8.7 7.3 16.4 16.9 14.7 51.2 11.6 7.7 30.8 7.9 19.6 33.1 0.0 0.6 0.9 0.6 0.4 0.2 1.6 1.9 3.1 0.8 2.3 0.2 1.0 1.2 0.5 0.3 0.2 10.9 1.4 0.4 0.6 0.6 0.6 0.4 0.2 0.4 0.4 0.8 0.4 AURKC "ARK3, AurC, STK13" ENSG00000105146 "Aurora kinase C" Q9UQB9 19 57230802-57235548 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "testis: 72.0" "Cell line enriched" "Detected in some" 7 "NTERA-2: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034859 Uncertain "HPA034859: AB_10670298" "unprognostic (7.27e-2)" "unprognostic (1.76e-1)" "unprognostic (6.45e-2)" "unprognostic (8.07e-3)" "unprognostic (3.29e-1)" "unprognostic (5.99e-2)" "unprognostic (1.11e-2)" "unprognostic (7.02e-2)" "unprognostic (1.13e-1)" "unprognostic (2.09e-1)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-5)" "unprognostic (4.26e-2)" "unprognostic (1.61e-1)" "unprognostic (1.55e-1)" "unprognostic (6.46e-4)" 0.6 0.5 0.9 0.9 1.2 0.7 1.5 0.7 2.0 0.4 0.6 0.6 0.2 0.0 0.8 1.3 0.5 0.6 2.6 0.9 0.9 1.1 0.8 1.8 1.3 2.2 1.2 0.2 0.4 0.5 0.1 1.3 1.2 1.7 0.5 0.8 1.1 0.5 0.9 2.3 0.6 0.4 1.1 2.1 3.4 0.4 72.0 0.6 0.7 0.8 1.0 1.3 0.5 0.4 2.1 1.0 1.7 1.0 1.0 0.6 0.2 0.2 0.1 0.7 0.3 0.2 0.7 0.3 1.2 0.6 0.9 3.4 0.8 0.1 0.0 0.1 0.5 0.0 0.0 0.7 0.6 0.0 3.7 0.1 0.3 0.0 1.1 0.0 0.2 0.9 0.7 0.7 0.5 0.6 0.1 0.0 1.2 0.0 1.1 0.6 29.3 0.8 0.1 0.2 0.6 0.6 1.2 1.4 0.4 0.0 0.2 0.1 0.1 1.3 0.3 0.2 4.1 0.3 0.7 1.4 1.8 0.6 0.8 0.0 0.0 0.0 0.1 1.7 0.6 1.0 0.0 1.9 0.0 0.0 0.9 2.1 0.0 0.0 0.1 1.0 0.3 1.0 0.0 0.2 0.9 1.2 0.7 1.6 0.9 1.1 1.2 0.2 1.7 0.6 AWAT1 DGAT2L3 ENSG00000204195 "Acyl-CoA wax alcohol acyltransferase 1" Q58HT5 X 70234655-70240627 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "breast: 3.8;skin 1: 6.1" "Cell line enhanced" "Detected in single" "HEK 293: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA063412 Enhanced "HPA063412: " "unprognostic (1.12e-1)" "unprognostic (1.78e-1)" "unprognostic (1.96e-2)" "unprognostic (4.90e-2)" "unprognostic (2.08e-1)" "unprognostic (6.78e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AWAT2 "DGAT2L4, MFAT" ENSG00000147160 "Acyl-CoA wax alcohol acyltransferase 2" Q6E213 X 70040542-70049938 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "breast: 5.7;skin 1: 14.0" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 2.3;PC-3: 2.6;SK-BR-3: 1.1" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA062748 Approved "HPA062748: " "unprognostic (3.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.99e-2)" "unprognostic (4.11e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (4.55e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219203-41261766 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 66.1;U-251 MG: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 8.8;plasmacytoid DC: 18.3" "Group enriched" "Detected in many" 14 "dendritic cells: 18.3;NK-cells: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" 61000000 "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: , HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavourable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 38.0 15.4 10.6 11.7 12.7 1.3 27.1 6.3 12.1 26.2 26.8 13.4 8.1 9.1 28.0 19.4 21.8 17.4 17.8 18.5 11.5 6.1 7.8 13.0 20.0 7.6 10.6 9.3 20.9 5.1 9.6 5.6 26.6 10.1 19.5 10.2 16.8 7.8 20.4 14.1 13.8 12.8 29.4 10.7 27.3 16.2 22.4 10.4 3.4 12.0 8.4 5.8 35.6 18.3 0.1 18.3 0.9 0.2 8.8 0.3 0.2 52.5 21.2 1.3 0.1 4.8 4.8 0.0 41.8 37.6 61.4 38.1 1.1 24.7 0.0 17.0 66.1 4.4 0.0 28.1 52.9 0.0 0.0 0.0 14.0 0.8 17.4 0.0 0.0 3.6 0.5 36.2 56.2 22.7 2.0 0.0 38.0 0.0 0.0 0.0 0.5 10.2 0.0 22.4 0.0 27.4 0.0 0.0 0.0 10.8 0.0 0.2 0.1 0.9 46.6 43.5 29.7 41.5 70.8 0.0 0.1 0.1 29.0 0.0 32.3 0.9 0.2 0.1 0.1 0.2 0.2 0.1 0.3 0.1 4.2 0.1 0.2 0.2 0.3 8.8 0.1 18.3 0.2 0.2 10.6 12.7 6.3 12.1 11.5 6.1 10.6 9.3 10.1 10.4 AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "bone marrow: 238.2" "Cell line enriched" "Detected in some" 7 "THP-1: 150.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "classical monocyte: 3.3;neutrophil: 7.6" "Group enriched" "Detected in many" 6 "granulocytes: 7.6;monocytes: 3.3" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" 290000 Vesicles "HPA055851: , HPA075964: " "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (4.44e-2)" "unprognostic (8.85e-3)" "unprognostic (1.62e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-3)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-6)" "unprognostic (1.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" "unprognostic (3.04e-2)" 0.3 0.2 0.4 0.2 0.5 238.2 0.6 0.0 0.6 0.2 0.2 1.0 0.0 0.2 0.2 0.2 0.2 0.8 0.2 34.6 0.4 0.5 0.2 1.5 15.3 0.2 0.2 0.0 0.5 0.1 0.1 0.9 3.8 0.2 0.2 0.2 0.2 0.6 0.2 1.0 0.4 0.2 0.2 0.1 18.6 0.2 1.2 0.0 20.6 1.3 0.0 0.2 0.1 0.4 0.0 0.8 7.6 3.3 0.0 0.3 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 150.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 3.3 0.2 0.3 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 7.6 0.0 0.5 0.0 0.0 4.1 0.4 0.5 0.0 0.6 0.4 0.5 0.2 0.0 0.2 0.0 B3GALNT1 "B3GALT3, beta3Gal-T3, galT3, GLOB, P1" ENSG00000169255 "Beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)" O75752 3 161083883-161105384 "Blood group antigen proteins, Enzymes, Plasma proteins, Predicted intracellular proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 36.8" "Cell line enhanced" "Detected in many" "PC-3: 16.9;RT4: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.9;NK-cell: 16.7" "Group enriched" "Detected in many" 7 "granulocytes: 4.9;NK-cells: 16.7" "Low region specificity" "Detected in all" HPA041204 Approved Vesicles 290000 Vesicles "HPA041204: AB_10795585" "unprognostic (3.85e-2)" "unprognostic (5.11e-3)" "unprognostic (3.02e-1)" "unprognostic (1.06e-2)" "unprognostic (7.83e-2)" "unprognostic (4.07e-2)" "unprognostic (9.26e-5)" "unprognostic (1.49e-2)" "unprognostic (1.12e-2)" "unprognostic (1.88e-2)" "unprognostic (3.44e-2)" "unprognostic (3.24e-1)" "unprognostic (2.09e-3)" "unprognostic (1.32e-1)" "unprognostic (4.90e-2)" "unprognostic (3.66e-2)" "unprognostic (3.19e-3)" 3.8 5.4 14.0 3.0 24.5 3.1 7.4 17.2 24.7 15.5 2.3 5.5 2.6 1.5 8.3 6.9 5.4 10.4 7.1 36.8 15.4 21.6 14.3 1.0 10.8 3.5 11.3 16.2 13.8 7.8 6.5 8.5 10.0 17.7 8.9 2.0 7.5 14.8 6.7 1.1 2.2 1.9 7.2 7.6 4.2 7.5 6.2 5.0 1.1 19.5 2.3 3.9 10.5 4.7 1.4 1.4 4.9 0.2 16.7 0.7 0.5 6.6 0.2 3.1 0.1 0.3 1.0 0.1 3.7 3.2 8.1 2.8 4.4 5.0 0.0 14.8 3.0 1.5 0.0 6.4 2.6 0.1 0.0 3.6 2.8 0.0 4.7 0.1 0.1 9.9 1.9 2.2 0.5 11.8 0.0 0.0 3.3 10.7 0.0 0.0 7.4 16.9 0.1 0.0 0.1 3.8 51.5 6.2 0.0 9.3 3.4 2.7 14.2 5.4 0.0 0.1 6.5 0.2 0.1 1.5 0.0 0.0 5.7 0.0 0.0 4.9 0.2 0.0 0.4 0.1 0.4 1.4 0.2 0.4 1.4 0.3 0.5 0.7 0.4 16.7 0.0 1.0 0.0 0.5 14.0 24.5 17.2 24.7 15.4 21.6 11.3 16.2 17.7 5.0 B3GALNT2 MGC39558 ENSG00000162885 "Beta-1,3-N-acetylgalactosaminyltransferase 2" Q8NCR0 1 235449923-235504481 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 35.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012502, HPA050662" Approved Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Nucleoplasm "Golgi apparatus" "HPA012502: AB_1845228, HPA050662: " "unprognostic (5.50e-2)" "unprognostic (3.16e-3)" "unprognostic (6.60e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (7.59e-3)" "unprognostic (1.96e-2)" "unprognostic (3.39e-2)" "unprognostic (3.38e-1)" "unprognostic (7.19e-3)" "unprognostic (2.89e-1)" "unprognostic (1.99e-1)" "unprognostic (5.52e-2)" "unprognostic (3.40e-1)" "unprognostic (3.53e-3)" "unprognostic (8.34e-3)" 5.0 6.3 3.9 4.3 5.1 1.3 8.4 4.7 4.5 5.4 7.6 3.5 5.1 3.3 8.0 8.7 10.3 6.1 9.7 7.9 2.8 2.9 3.7 4.6 3.7 3.1 3.0 3.2 5.9 35.7 9.8 8.9 4.5 4.7 8.3 5.8 8.5 8.7 7.3 21.6 6.1 6.9 16.9 2.5 3.3 9.2 5.8 3.9 4.7 7.1 7.0 5.0 9.7 5.9 1.5 5.7 2.4 2.7 1.9 1.9 1.3 10.0 6.6 7.3 10.8 11.8 10.0 17.6 8.8 8.0 6.7 6.2 5.1 9.0 5.3 11.7 10.0 12.7 14.2 10.3 8.2 10.4 9.8 3.3 8.4 5.8 7.5 10.8 3.7 7.2 6.7 6.9 16.6 10.2 8.1 7.1 6.2 4.8 6.8 3.9 10.4 3.8 7.5 12.2 13.4 4.3 12.0 9.4 12.0 15.3 5.8 7.6 11.1 11.0 10.0 5.9 9.7 9.9 11.8 10.4 8.5 3.2 3.8 7.8 13.6 2.4 2.3 1.1 1.1 2.7 1.7 1.5 0.8 1.9 5.7 1.1 1.0 1.3 0.2 1.9 2.5 3.1 0.5 1.3 3.9 5.1 4.7 4.5 2.8 2.9 3.0 3.2 4.7 3.9 B3GALT2 beta3Gal-T2 ENSG00000162630 "Beta-1,3-galactosyltransferase 2" O43825 1 193179045-193186654 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.9;gallbladder: 19.0;heart muscle: 25.1" "Group enriched" "Detected in some" 4 "AF22: 16.0;ASC TERT1: 7.3;LHCN-M2: 10.9;WM-115: 19.0" "Cancer enhanced" "Detected in some" "glioma: 2.4" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "MAIT T-cell: 11.9" "Lineage enriched" "Detected in single" 57 "T-cells: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078659 Approved "Plasma membrane,Microtubules" "Plasma membrane, Microtubules" "HPA078659: " "unprognostic (1.83e-2)" "unprognostic (3.81e-2)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (1.58e-3)" "unprognostic (2.34e-3)" "unprognostic (2.43e-3)" "unprognostic (1.63e-1)" "unprognostic (2.44e-1)" "unprognostic (6.14e-4)" "unprognostic (4.41e-2)" "unprognostic (8.10e-3)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-3)" 0.7 2.0 11.3 1.3 8.9 0.7 0.9 1.4 32.9 0.8 1.7 1.2 0.9 1.6 0.6 1.8 1.2 0.7 19.0 25.1 10.1 7.9 1.7 0.8 2.6 0.7 5.7 19.1 13.8 0.8 0.4 0.9 0.9 5.0 6.5 2.0 0.3 0.5 7.1 0.6 0.7 4.1 0.8 6.5 1.4 2.1 1.4 4.7 0.0 1.8 0.0 1.6 2.0 0.7 0.0 0.2 0.1 0.0 0.0 11.9 0.3 0.0 0.0 16.0 0.0 0.4 7.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.4 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 0.0 0.0 0.2 0.0 11.9 0.0 2.7 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.3 0.3 11.3 8.9 1.4 32.9 10.1 7.9 5.7 19.1 5.0 4.7 B3GALT4 "beta3Gal-T4, GalT4" ENSG00000235863 "Beta-1,3-galactosyltransferase 4" O96024 6 33277132-33284832 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.1;SCLC-21H: 3.1;SK-BR-3: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043001 Approved "HPA043001: " "unprognostic (3.71e-2)" "unprognostic (1.33e-2)" "unprognostic (6.02e-2)" "unprognostic (1.00e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-2)" "unprognostic (6.00e-2)" "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.98e-2)" "unprognostic (1.96e-1)" "unprognostic (1.17e-3)" "unprognostic (6.83e-2)" "unprognostic (1.94e-1)" "unprognostic (1.22e-2)" "unprognostic (3.75e-2)" 7.0 6.9 3.0 9.8 4.0 3.0 6.7 5.3 6.3 7.6 9.0 6.2 13.1 8.0 6.2 7.0 14.0 6.1 9.4 5.7 3.6 3.4 7.1 1.7 6.7 11.9 3.7 3.0 3.1 3.1 5.3 4.4 7.4 4.0 6.5 4.9 6.7 9.1 15.9 2.7 10.9 12.5 4.3 4.6 11.1 7.7 19.0 2.5 14.7 5.6 5.3 9.8 8.6 7.9 7.3 4.1 12.4 8.4 6.3 9.5 5.2 0.0 0.3 0.6 0.2 0.9 1.6 0.8 0.3 0.4 0.0 0.1 0.0 5.1 0.0 0.0 0.7 2.6 0.0 0.2 0.0 2.8 0.3 0.9 0.4 0.0 1.0 0.0 2.7 2.1 1.3 0.1 0.1 0.7 0.0 0.3 0.0 0.1 1.3 1.2 0.2 0.3 0.2 0.0 0.0 0.0 0.8 3.1 0.4 0.1 5.2 0.4 0.0 1.4 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.7 12.4 6.9 10.0 9.5 6.7 7.4 6.0 5.9 8.0 4.1 7.3 5.7 5.1 7.3 6.3 8.4 3.3 6.3 5.2 3.0 4.0 5.3 6.3 3.6 3.4 3.7 3.0 4.0 2.5 B3GAT1 "CD57, GlcAT-P, HNK-1, LEU7, NK-1" ENSG00000109956 "Beta-1,3-glucuronyltransferase 1" Q9P2W7 11 134378504-134411918 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 76.0" "Cell line enhanced" "Detected in some" "AF22: 17.0;HMC-1: 18.8;NTERA-2: 16.3;SH-SY5Y: 6.2" "Group enriched" "Detected in some" 11 "glioma: 10.8;prostate cancer: 3.5;thyroid cancer: 4.1" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 3.8;naive CD8 T-cell: 2.4" "Lineage enriched" "Detected in single" 39 "T-cells: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002500, CAB010893, HPA069468" Enhanced Supported Vesicles "Secreted in brain" Vesicles "CAB002500: AB_563601, CAB010893: AB_1078474, HPA069468: " "unprognostic (6.72e-2)" "unprognostic (3.97e-4)" "unprognostic (2.13e-2)" "unprognostic (1.40e-3)" "unprognostic (5.52e-2)" "unprognostic (2.60e-3)" "unprognostic (6.30e-2)" "unprognostic (1.96e-2)" "unprognostic (8.74e-2)" "unprognostic (2.72e-1)" "unprognostic (1.57e-3)" "unprognostic (1.58e-1)" "unprognostic (9.34e-3)" "unprognostic (3.87e-3)" "unprognostic (2.42e-1)" "unprognostic (4.07e-2)" "unprognostic (2.26e-2)" 1.5 5.8 38.9 1.7 23.7 2.1 5.6 9.2 76.0 1.7 1.5 25.8 0.0 1.8 1.6 1.7 1.4 1.6 1.7 1.5 43.4 14.9 2.1 6.0 1.8 3.3 30.3 19.5 1.5 1.7 1.4 0.9 1.4 19.7 4.2 1.5 2.1 2.2 1.8 1.4 1.8 1.6 1.5 45.1 2.1 6.0 1.8 25.2 0.0 7.7 0.0 1.7 2.5 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.4 0.0 0.0 17.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 2.9 0.0 0.8 1.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 16.3 0.0 0.3 0.0 1.2 0.0 0.1 2.3 6.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.2 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.8 1.9 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.4 38.9 23.7 9.2 33.7 43.4 14.9 30.3 19.5 19.7 25.2 B3GAT2 GlcAT-S ENSG00000112309 "Beta-1,3-glucuronyltransferase 2" Q9NPZ5 6 70856679-70957038 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 27.2" "Cell line enriched" "Detected in some" 20 "SCLC-21H: 22.2" "Group enriched" "Detected in some" 20 "glioma: 4.7;testis cancer: 1.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012059 Uncertain "HPA012059: AB_2061050" "unprognostic (7.10e-3)" "unprognostic (7.81e-2)" "unprognostic (1.63e-1)" "unprognostic (1.10e-3)" "unprognostic (2.21e-1)" "unprognostic (1.22e-2)" "unprognostic (1.96e-2)" "unprognostic (4.88e-2)" "unprognostic (4.22e-2)" "unprognostic (9.16e-4)" "unprognostic (8.09e-2)" "unprognostic (7.43e-3)" "unprognostic (6.88e-7)" "unprognostic (2.72e-2)" "unprognostic (3.35e-2)" "unprognostic (2.53e-2)" "unprognostic (3.45e-3)" 1.8 1.5 9.5 1.9 7.8 1.6 1.1 3.2 27.2 0.8 1.1 26.2 0.0 2.3 1.4 1.1 1.4 1.1 1.4 1.5 19.2 11.5 1.0 1.3 1.2 2.0 9.7 13.6 1.1 2.2 0.8 0.5 1.2 21.0 1.3 0.9 0.4 1.5 0.9 1.5 1.9 2.4 1.1 17.3 2.0 1.5 2.9 16.3 0.0 1.5 0.0 0.9 1.3 0.9 1.2 1.0 2.0 1.2 1.1 2.2 0.2 0.3 0.0 0.6 0.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.2 1.1 0.1 0.3 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.0 0.5 0.7 0.1 0.1 0.2 0.2 0.0 0.2 22.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.5 0.0 0.1 0.1 0.1 0.1 1.3 1.2 1.2 1.0 1.0 0.9 1.0 1.5 2.1 0.4 1.2 1.7 1.8 2.0 1.1 1.1 1.0 2.2 0.2 9.5 7.8 3.2 11.2 19.2 11.5 9.7 13.6 21.0 16.3 B3GAT3 GlcAT-I ENSG00000149541 "Beta-1,3-glucuronyltransferase 3" O94766 11 62615296-62622175 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051328 Approved "Intracellular and membrane" 1600000 "HPA051328: " "unprognostic (1.55e-1)" "unprognostic (3.93e-2)" "unprognostic (8.45e-3)" "unprognostic (2.31e-1)" "prognostic unfavourable (4.69e-4)" "unprognostic (3.80e-2)" "prognostic unfavourable (5.11e-6)" "unprognostic (4.94e-2)" "unprognostic (2.42e-1)" "unprognostic (3.66e-2)" "unprognostic (1.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.58e-3)" "unprognostic (1.46e-3)" "unprognostic (6.00e-2)" "unprognostic (4.48e-2)" "unprognostic (2.58e-2)" 14.4 21.6 24.8 15.9 29.2 15.0 19.7 28.9 29.1 15.4 12.9 24.2 8.1 17.6 14.9 18.8 10.6 21.1 15.3 13.1 25.8 25.6 17.4 21.5 12.8 22.9 30.0 16.8 17.0 22.4 18.5 25.6 19.9 25.7 18.2 6.8 19.0 24.9 20.9 6.4 23.1 16.5 14.2 24.4 17.5 15.5 12.0 24.8 17.5 14.5 5.4 12.9 14.4 17.4 11.2 15.7 15.7 18.9 24.5 14.1 9.4 9.7 16.1 8.8 15.3 12.1 11.9 6.5 8.1 11.5 7.7 8.7 7.1 14.5 8.6 28.1 8.2 6.3 8.9 8.1 1.7 19.2 17.2 4.1 7.4 9.0 29.2 5.8 9.7 21.2 13.8 10.1 4.2 6.8 13.7 21.7 9.1 24.8 9.9 20.8 13.6 15.1 10.1 6.3 47.4 16.0 1.9 9.3 15.3 9.3 11.0 37.1 14.8 11.5 5.3 7.9 6.1 20.9 15.6 22.7 7.6 10.0 23.9 10.5 16.4 15.7 18.4 15.5 14.1 18.3 9.3 11.2 9.8 11.4 15.7 9.1 9.8 11.4 5.4 24.5 18.9 9.3 11.7 9.4 24.8 29.2 28.9 27.7 25.8 25.6 30.0 16.8 25.7 24.8 B3GNT2 "B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT" ENSG00000170340 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2" Q9NY97 2 62196113-62224731 "Enzymes, Plasma proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005997 Approved Approved Vesicles 43000000 Vesicles "HPA005997: AB_1845234" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (1.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.51e-1)" "unprognostic (1.55e-2)" "unprognostic (2.13e-2)" "unprognostic (3.76e-1)" "prognostic unfavourable (1.62e-4)" "unprognostic (3.63e-1)" "unprognostic (1.11e-2)" "unprognostic (9.55e-2)" "unprognostic (3.05e-2)" "unprognostic (3.18e-1)" "unprognostic (1.25e-1)" 18.9 14.3 8.6 10.8 23.0 41.6 17.5 3.1 14.1 18.4 17.9 7.4 5.6 17.9 19.8 8.0 24.5 8.7 18.1 20.9 7.6 11.5 24.4 14.2 23.9 13.9 9.7 7.1 9.0 43.2 5.4 25.9 22.8 9.5 7.5 16.3 14.4 17.2 6.0 5.2 13.0 21.7 16.3 7.6 14.6 12.0 7.0 10.6 27.0 15.6 8.5 18.5 11.8 14.7 8.4 6.8 28.3 5.6 20.3 19.3 8.2 7.6 5.3 8.1 3.5 8.9 4.0 23.3 7.5 8.3 6.0 8.0 10.9 12.4 8.3 6.9 6.9 7.4 5.1 6.3 10.4 17.3 4.1 20.5 2.5 6.4 6.7 12.2 9.2 4.9 11.9 11.5 4.1 8.9 11.1 5.2 7.2 5.8 23.2 18.3 7.7 2.2 42.6 5.6 4.5 11.4 7.5 7.8 5.8 5.3 11.5 8.6 3.3 14.4 10.1 7.3 6.4 12.2 7.4 14.8 5.2 35.9 5.7 21.2 7.0 7.2 4.5 28.3 11.0 4.4 15.6 7.6 8.2 19.3 5.5 8.4 9.9 14.4 11.3 20.3 5.6 6.8 13.2 8.2 8.6 23.0 3.1 14.1 7.6 11.5 9.7 7.1 9.5 10.6 B3GNT3 "B3GN-T3, B3GNT-3, beta3Gn-T3, HP10328, TMEM3" ENSG00000179913 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3" Q9Y2A9 19 17794828-17813082 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 69.9;intestine: 61.6;placenta: 56.0" "Cell line enhanced" "Detected in some" "A-431: 17.8;BEWO: 17.6;CAPAN-2: 47.7;EFO-21: 12.2;RT4: 17.1;SK-BR-3: 16.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory CD4 T-cell: 2.7;memory CD8 T-cell: 1.1;naive CD4 T-cell: 3.2" "Lineage enriched" "Detected in single" 32 "T-cells: 3.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA024298 Enhanced "Intracellular and membrane" "HPA024298: AB_1845236" "unprognostic (1.10e-1)" "unprognostic (5.19e-2)" "unprognostic (1.84e-1)" "unprognostic (4.84e-3)" "unprognostic (1.10e-1)" "unprognostic (1.18e-1)" "prognostic unfavourable (4.25e-5)" "unprognostic (3.26e-1)" "unprognostic (4.64e-2)" "prognostic unfavourable (2.16e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (7.38e-2)" "unprognostic (1.26e-1)" "unprognostic (7.10e-2)" "unprognostic (2.57e-2)" 0.4 0.2 0.2 8.7 0.3 0.0 1.8 0.2 0.3 3.5 25.3 0.0 12.0 16.6 0.4 1.2 15.1 0.6 69.9 0.5 0.2 0.3 11.4 2.5 1.0 1.2 0.2 0.0 0.3 9.1 0.0 0.3 56.0 0.0 4.4 22.4 0.3 24.4 12.8 0.3 2.0 61.6 1.9 0.2 0.3 21.8 0.3 0.0 0.3 0.4 2.6 18.3 10.2 5.4 0.0 0.0 0.0 0.0 0.0 3.2 0.6 17.8 4.7 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.2 47.7 0.0 12.2 0.0 1.7 0.0 5.7 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 7.7 0.0 0.0 0.4 10.6 17.1 0.0 0.0 0.0 16.2 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 1.1 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.2 0.3 0.2 0.3 0.2 0.0 0.0 0.0 B3GNT4 "B3GN-T4, beta3Gn-T4" ENSG00000176383 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4" Q9C0J1 12 122203543-122208952 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.3;skin 1: 8.5" "Cell line enhanced" "Detected in many" "HDLM-2: 8.0;hTCEpi: 9.7;T-47d: 7.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055261 Uncertain Approved Nucleoli,Mitochondria Mitochondria Nucleoli "HPA055261: " "unprognostic (1.67e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.60e-2)" "unprognostic (1.32e-3)" "unprognostic (1.98e-1)" "unprognostic (3.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.82e-2)" "unprognostic (3.69e-1)" "prognostic unfavourable (3.52e-6)" "unprognostic (1.24e-1)" "unprognostic (2.79e-1)" "unprognostic (8.97e-2)" "unprognostic (9.47e-2)" 0.7 3.2 7.3 0.8 6.8 4.6 0.8 16.3 9.1 0.5 0.7 0.5 0.0 1.0 0.6 0.7 1.8 1.1 1.1 0.8 4.9 4.0 6.1 0.6 1.1 0.9 1.5 7.3 0.8 0.8 0.8 1.9 0.8 4.0 0.7 0.6 1.0 1.7 0.7 1.1 8.5 1.0 0.6 0.6 1.0 0.7 2.0 0.3 0.0 0.8 0.3 0.8 0.6 0.5 0.8 1.0 0.8 1.7 0.4 1.9 0.4 5.4 1.0 0.3 2.1 0.2 0.1 1.0 0.1 0.0 0.3 0.6 3.4 0.4 0.5 0.9 0.0 2.0 2.6 2.1 0.1 8.0 2.8 0.2 1.5 0.3 0.6 0.7 1.1 0.7 9.7 0.1 0.4 0.0 1.5 0.6 0.2 4.8 0.0 0.7 0.6 2.0 0.4 0.6 1.0 1.4 0.6 1.3 1.7 1.5 1.0 0.5 7.5 0.1 0.1 0.5 2.8 0.5 0.3 0.6 4.9 1.2 0.5 0.8 0.3 0.8 0.4 0.2 0.8 0.1 0.4 0.8 1.3 0.2 0.2 0.5 1.9 0.2 0.5 0.4 1.7 1.0 0.6 0.4 7.3 6.8 16.3 8.1 4.9 4.0 1.5 7.3 4.0 0.3 B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253244-183298504 "Enzymes, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 80.2" "Cell line enhanced" "Detected in many" "HBEC3-KT: 25.8;hTCEpi: 31.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 6 "neutrophil: 9.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.0" "Region enriched" "Detected in single" 12 "cerebellum: 16.5" "Low region specificity" "Detected in many" HPA017292 Uncertain Approved Nucleoli Nucleoli "HPA017292: AB_1845237" "unprognostic (2.17e-1)" "unprognostic (5.73e-2)" "unprognostic (1.07e-2)" "unprognostic (4.83e-3)" "unprognostic (1.89e-1)" "unprognostic (3.08e-2)" "prognostic unfavourable (5.09e-4)" "unprognostic (7.10e-3)" "unprognostic (7.78e-2)" "unprognostic (8.48e-2)" "prognostic unfavourable (7.23e-6)" "unprognostic (4.20e-1)" "prognostic unfavourable (1.30e-7)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (3.53e-2)" "unprognostic (8.10e-3)" 8.6 1.4 2.2 6.1 2.3 31.6 4.3 1.2 2.5 6.4 29.8 5.4 2.1 17.5 3.2 5.4 23.5 5.4 10.1 3.3 3.0 2.9 3.5 3.0 11.2 5.1 4.0 0.7 4.2 3.5 1.8 5.1 19.8 4.5 3.9 9.2 3.2 8.7 2.5 6.6 8.0 80.2 2.9 6.3 2.3 5.1 2.9 2.3 1.0 4.6 18.9 8.9 5.0 10.6 0.1 1.1 9.0 1.5 0.0 0.3 0.4 16.4 1.6 8.9 5.4 7.4 22.0 8.0 0.2 0.4 1.7 1.4 3.3 8.7 0.0 1.0 0.0 7.6 9.1 25.8 1.4 0.0 5.6 0.8 0.7 0.0 9.5 8.3 4.1 10.3 31.4 1.4 23.5 16.0 9.4 0.0 14.1 0.0 0.0 2.7 3.7 14.3 2.6 4.5 0.0 5.4 4.6 0.4 8.5 4.6 0.0 1.9 0.0 10.1 23.6 0.4 3.5 0.5 4.0 0.0 0.0 0.0 3.3 19.6 8.8 0.0 1.5 1.5 0.0 0.3 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.3 0.4 2.2 2.3 1.2 2.5 3.0 2.9 4.0 0.7 4.5 2.3 B3GNT6 B3Gn-T6 ENSG00000198488 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6" Q6ZMB0 11 77034398-77041973 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 15.8;lymphoid tissue: 17.5;stomach 1: 17.9" "Cell line enhanced" "Detected in some" "MCF7: 2.0;RPMI-8226: 1.5" "Group enriched" "Detected in some" 14 "colorectal cancer: 6.3;lung cancer: 3.9;pancreatic cancer: 5.1;prostate cancer: 5.0;stomach cancer: 4.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 2.3;neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039805 Enhanced "Intracellular and membrane" "HPA039805: " "unprognostic (1.71e-1)" "prognostic favourable (2.31e-4)" "unprognostic (4.79e-2)" "unprognostic (5.42e-2)" "unprognostic (7.64e-2)" "unprognostic (1.95e-1)" "unprognostic (2.72e-1)" "unprognostic (1.23e-2)" "unprognostic (7.77e-2)" "unprognostic (2.19e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-1)" 0.2 0.2 0.3 6.6 0.4 0.0 0.2 0.3 0.4 0.5 15.8 0.0 0.0 3.7 0.2 0.0 2.5 0.2 0.9 0.2 0.3 0.3 0.2 0.2 1.4 0.0 0.3 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.3 12.4 0.0 1.6 0.0 0.2 0.2 9.4 0.0 0.2 0.2 17.9 0.6 0.0 0.0 0.2 3.4 17.5 0.2 0.3 0.4 0.3 2.3 0.2 0.8 0.5 0.2 0.1 0.0 0.5 0.5 0.0 0.2 0.2 0.1 0.2 0.5 0.1 1.1 0.2 0.7 0.3 0.0 0.0 0.1 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.6 0.2 0.5 0.4 0.0 0.0 0.0 0.2 0.6 0.0 2.0 0.2 0.5 0.7 0.0 0.0 0.1 1.5 0.0 0.3 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.1 0.3 0.4 0.5 0.3 0.1 0.2 0.2 2.3 0.2 0.3 0.4 0.2 0.5 0.2 0.2 0.2 0.0 0.4 0.3 0.3 2.2 0.8 0.0 0.3 0.1 0.2 0.3 0.4 0.3 0.4 0.3 0.3 0.3 0.0 0.0 0.0 B4GALNT1 "beta1-4GalNAc-T, GALGT, SPG26" ENSG00000135454 "Beta-1,4-N-acetyl-galactosaminyltransferase 1" Q00973 12 57623410-57633355 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.4" "Cell line enhanced" "Detected in many" "EFO-21: 22.0;HDLM-2: 18.7" "Cancer enriched" "Detected in many" 6 "glioma: 10.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "gdT-cell: 1.9" "Lineage enhanced" "Detected in single" "T-cells: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008968 Enhanced "Intracellular and membrane" 9500 "HPA008968: AB_1078253" "unprognostic (3.18e-1)" "unprognostic (8.34e-2)" "unprognostic (2.05e-2)" "unprognostic (3.33e-3)" "unprognostic (2.54e-1)" "unprognostic (2.70e-3)" "unprognostic (3.73e-5)" "unprognostic (1.26e-2)" "unprognostic (1.72e-1)" "unprognostic (2.66e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "prognostic unfavourable (3.18e-14)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (1.44e-2)" "unprognostic (4.92e-4)" 3.0 2.1 12.9 2.3 16.4 1.0 1.5 26.5 32.4 1.9 2.4 1.0 0.0 1.4 2.2 3.8 1.3 1.4 1.5 3.9 15.3 11.2 1.3 1.3 1.7 1.6 6.5 14.3 1.0 1.2 1.1 1.0 1.3 11.6 4.2 2.2 1.6 3.2 6.8 8.1 1.6 1.9 3.2 2.3 1.3 1.4 1.6 2.3 0.0 1.3 0.6 1.8 1.5 0.9 0.0 0.0 0.0 0.0 0.8 1.9 0.0 2.8 14.6 3.2 5.6 0.2 0.0 0.0 1.4 3.0 6.0 6.4 0.9 7.6 0.8 22.0 4.1 1.4 2.5 1.1 2.0 18.7 0.9 0.2 3.7 4.8 0.2 0.7 1.4 0.0 0.4 3.6 0.2 0.1 2.3 4.6 1.0 3.8 0.6 0.0 3.8 2.9 0.0 4.4 2.3 0.0 0.0 12.3 3.1 0.8 0.4 0.1 2.7 1.0 0.0 3.5 8.3 6.9 9.1 11.5 8.6 0.8 8.1 0.9 9.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 12.9 16.4 26.5 25.9 15.3 11.2 6.5 14.3 11.6 2.3 B4GALNT3 "B4GalNac-T3, FLJ16224, FLJ40362" ENSG00000139044 "Beta-1,4-N-acetyl-galactosaminyltransferase 3" Q6L9W6 12 460364-563509 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 43.1" "Cell line enhanced" "Detected in some" "BEWO: 25.8;HDLM-2: 9.1;HEK 293: 9.1;NTERA-2: 11.4;U-937: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011404 Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" "Golgi apparatus" Vesicles "HPA011404: AB_1845242" "unprognostic (2.38e-2)" "unprognostic (9.59e-3)" "unprognostic (1.38e-1)" "prognostic favourable (1.69e-10)" "unprognostic (4.22e-2)" "unprognostic (4.63e-2)" "unprognostic (1.46e-2)" "unprognostic (9.53e-3)" "unprognostic (3.29e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (9.99e-3)" "unprognostic (2.82e-1)" "unprognostic (2.48e-2)" "unprognostic (2.98e-1)" 0.3 5.7 1.4 2.1 3.8 1.5 1.1 0.3 8.2 6.1 12.8 0.6 0.4 0.8 8.5 2.9 6.0 3.4 9.6 16.8 5.6 0.9 4.1 0.3 6.2 0.2 0.9 1.7 2.1 7.9 2.5 14.7 0.1 2.0 1.6 9.8 1.5 3.8 1.1 2.7 11.0 1.7 1.9 0.5 0.4 43.1 8.0 0.1 1.0 2.1 9.1 4.1 1.8 4.0 0.0 0.0 0.7 0.1 0.0 1.4 0.0 0.0 0.0 0.2 0.9 0.0 0.0 25.8 0.0 0.0 0.0 0.0 6.4 5.0 0.0 0.6 0.0 2.8 6.4 0.7 0.0 9.1 9.1 0.0 0.0 1.3 0.0 0.0 3.8 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.4 0.5 0.4 3.5 0.0 6.2 5.5 3.1 2.0 0.6 0.2 0.7 0.6 2.0 0.0 0.0 2.0 0.2 0.6 0.0 0.1 0.1 0.0 11.1 4.3 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.4 3.8 0.3 8.2 5.6 0.9 0.9 1.7 2.0 0.1 B4GALNT4 "FLJ25045, NGalNAc-T1" ENSG00000182272 "Beta-1,4-N-acetyl-galactosaminyltransferase 4" Q76KP1 11 369796-382116 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.1;ovary: 18.6" "Cell line enhanced" "Detected in many" "AF22: 19.7;NTERA-2: 17.6;SCLC-21H: 21.9;SH-SY5Y: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053126 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle" "Intracellular and membrane" "Nucleoplasm, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA053126: " "unprognostic (6.11e-2)" "unprognostic (7.82e-2)" "unprognostic (1.79e-1)" "unprognostic (6.92e-3)" "unprognostic (5.36e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-1)" "unprognostic (1.53e-1)" "unprognostic (1.69e-3)" "unprognostic (4.99e-3)" "unprognostic (1.52e-10)" "unprognostic (9.01e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-4)" "unprognostic (1.25e-1)" 1.6 2.5 20.6 2.8 16.7 1.2 3.5 26.5 35.1 5.9 2.0 8.6 0.8 2.4 8.6 2.4 1.8 8.7 2.1 1.4 17.6 16.8 1.2 1.1 1.3 1.6 11.5 14.9 18.6 1.8 6.3 6.1 1.1 13.0 3.8 1.6 2.3 4.0 3.7 1.1 3.8 2.9 3.1 8.3 1.5 1.5 1.8 11.0 0.0 1.1 0.0 1.7 1.3 1.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.6 19.7 11.3 0.0 0.0 4.6 3.5 0.9 1.6 0.5 2.0 0.0 0.0 2.6 0.4 0.7 2.6 4.7 0.5 0.0 6.7 0.0 6.2 6.1 0.2 0.0 4.8 0.3 2.8 0.1 2.1 0.2 6.0 0.0 0.0 5.8 0.2 0.0 17.6 7.7 0.0 0.0 2.6 0.2 0.0 21.9 26.7 1.3 0.9 0.2 7.7 0.0 4.8 1.1 6.3 1.9 0.2 0.0 0.9 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.6 16.7 26.5 21.2 17.6 16.8 11.5 14.9 13.0 11.0 B4GALT1 "beta4Gal-T1, GGTB2" ENSG00000086062 "Beta-1,4-galactosyltransferase 1" P15291 9 33104082-33167356 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 55.7;SiHa: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 56.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010806, HPA010807" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" 98000000 "Golgi apparatus" "HPA010806: AB_1078255, HPA010807: AB_1078254" "unprognostic (7.57e-2)" "unprognostic (1.24e-2)" "unprognostic (2.09e-1)" "prognostic favourable (6.85e-7)" "unprognostic (1.83e-2)" "unprognostic (9.94e-2)" "unprognostic (3.08e-2)" "prognostic unfavourable (1.25e-4)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.68e-3)" "unprognostic (2.78e-1)" "unprognostic (7.93e-3)" "unprognostic (4.98e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.46e-2)" 32.0 19.5 4.5 22.5 4.5 22.1 35.1 5.9 3.5 25.4 20.4 6.4 29.1 6.5 19.5 34.1 24.7 26.3 24.2 33.1 3.2 2.5 31.7 91.2 34.9 44.9 5.8 2.2 56.8 20.1 30.2 11.9 79.0 5.9 22.6 11.1 32.1 39.1 42.7 15.0 17.6 18.9 17.7 6.4 38.5 19.9 37.6 3.6 23.1 39.3 16.9 41.0 26.4 21.6 24.8 56.4 24.9 9.1 18.2 16.5 5.4 15.9 11.8 2.2 3.0 11.2 19.8 39.9 16.6 20.9 10.0 10.0 7.2 18.6 6.1 10.6 24.2 8.6 2.2 20.6 10.1 55.7 2.2 3.5 49.2 5.5 22.1 2.8 5.9 22.1 36.9 11.4 14.0 10.6 3.9 7.6 9.5 13.9 2.5 5.7 1.3 3.6 3.4 2.0 4.0 30.1 13.9 1.6 2.1 105.0 20.5 4.1 25.9 5.2 9.8 7.2 8.5 23.1 6.4 1.2 2.8 3.8 22.3 3.9 2.6 6.2 9.1 5.0 13.0 7.8 16.5 24.8 8.7 11.4 6.1 20.7 5.3 6.7 24.9 18.2 6.0 56.4 5.7 5.4 4.5 4.5 5.9 3.5 3.2 2.5 5.8 2.2 5.9 3.6 B4GALT2 beta4Gal-T2 ENSG00000117411 "Beta-1,4-galactosyltransferase 2" O60909 1 43978943-43991170 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007620, HPA047739" Supported Supported "Golgi apparatus,Vesicles" 12000 "Golgi apparatus, Vesicles" "HPA007620: , HPA047739: " "unprognostic (1.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.15e-1)" "unprognostic (7.59e-2)" "unprognostic (1.19e-1)" "unprognostic (2.35e-1)" "prognostic unfavourable (2.96e-5)" "unprognostic (1.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.08e-2)" "unprognostic (4.23e-3)" "unprognostic (7.58e-2)" "prognostic unfavourable (3.62e-5)" "unprognostic (6.54e-2)" "unprognostic (1.52e-1)" "unprognostic (7.66e-2)" "unprognostic (3.12e-3)" 18.6 8.6 34.5 10.1 22.4 4.6 15.6 8.1 35.7 18.4 16.1 16.1 10.7 9.4 13.3 8.5 20.2 11.4 11.9 23.3 25.3 18.9 8.4 24.2 7.7 4.4 18.9 15.6 15.3 39.5 9.9 10.6 9.9 12.7 13.5 10.4 8.7 21.4 21.5 41.0 19.5 9.4 21.3 16.1 5.2 11.2 11.4 11.3 1.9 9.0 12.1 10.1 16.5 11.7 1.7 0.4 0.1 0.6 0.2 2.6 0.7 19.8 14.5 15.2 25.8 20.6 18.5 15.2 22.6 18.6 18.0 16.5 9.5 17.6 13.1 11.5 36.0 13.8 13.5 23.1 8.4 13.2 25.7 8.7 10.1 21.8 16.7 8.3 0.3 16.1 27.0 12.9 26.4 20.8 16.4 8.5 14.0 14.3 4.3 8.3 21.1 18.2 15.6 20.4 20.5 12.7 9.3 27.6 22.9 9.9 31.2 15.1 13.6 9.9 16.3 31.3 40.2 21.6 25.1 3.0 5.9 5.6 14.0 6.3 20.9 0.0 0.2 0.0 2.6 0.6 2.4 1.7 1.2 2.2 0.4 0.5 0.0 2.0 0.1 0.2 0.1 0.2 1.1 0.7 34.5 22.4 8.1 35.7 25.3 18.9 18.9 15.6 12.7 11.3 B4GALT3 beta4Gal-T3 ENSG00000158850 "Beta-1,4-galactosyltransferase 3" O60512 1 161171310-161177968 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010793 Approved Supported "Golgi apparatus,Cytosol" 74000 "Golgi apparatus" Cytosol "HPA010793: AB_1078256" "unprognostic (5.67e-3)" "unprognostic (7.68e-3)" "unprognostic (1.20e-2)" "unprognostic (8.15e-3)" "unprognostic (3.91e-1)" "unprognostic (1.10e-2)" "prognostic unfavourable (5.87e-5)" "unprognostic (3.11e-2)" "unprognostic (3.13e-1)" "unprognostic (4.64e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-1)" "prognostic unfavourable (7.12e-7)" "unprognostic (1.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.66e-1)" "unprognostic (1.38e-1)" 20.7 18.7 16.5 17.2 22.1 17.3 33.4 20.1 23.2 15.0 19.0 12.4 22.2 18.4 13.6 21.0 20.4 17.2 17.5 17.2 13.4 14.7 22.5 21.7 20.8 21.6 16.4 13.4 25.4 37.5 15.8 29.1 41.0 16.6 18.5 19.3 14.8 33.0 27.8 19.5 20.2 15.1 11.7 14.1 26.6 21.5 28.4 16.4 14.8 28.2 10.7 21.4 20.6 22.9 16.7 22.6 7.1 12.6 15.1 25.5 11.9 9.7 6.5 9.6 12.7 14.3 7.3 15.3 5.6 10.0 11.6 10.7 12.7 19.9 9.0 16.0 6.2 9.9 10.1 6.2 6.9 9.4 12.3 5.1 4.3 10.2 10.3 10.1 14.4 10.2 9.2 10.7 11.6 13.1 16.6 20.3 9.4 10.1 6.6 9.7 12.0 13.8 8.0 5.4 22.2 9.8 6.0 13.7 16.2 5.6 14.8 11.7 14.8 18.5 5.5 5.8 10.5 6.5 16.2 73.3 39.5 12.0 8.6 8.7 9.2 5.1 8.9 7.1 17.6 10.1 15.7 16.7 16.7 16.8 10.8 13.5 16.4 15.4 5.9 15.1 12.6 22.6 25.5 11.9 16.5 22.1 20.1 23.2 13.4 14.7 16.4 13.4 16.6 16.4 B4GALT4 beta4Gal-T4 ENSG00000121578 "Beta-1,4-galactosyltransferase 4" O60513 3 119211732-119241103 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046819, HPA063546" Approved Supported "Golgi apparatus" "Intracellular and membrane" "Golgi apparatus" "HPA046819: AB_2679824, HPA063546: " "unprognostic (4.07e-2)" "unprognostic (1.78e-2)" "unprognostic (3.27e-2)" "unprognostic (1.14e-3)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "prognostic unfavourable (4.04e-4)" "unprognostic (6.30e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-1)" "unprognostic (6.10e-3)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" 9.6 7.7 7.0 8.6 8.5 11.6 8.8 5.3 6.6 10.1 20.8 8.2 12.6 14.6 15.1 43.4 13.2 12.6 21.3 11.1 6.0 6.2 15.0 11.8 8.9 8.0 7.7 7.3 13.5 20.8 8.5 16.2 23.7 9.1 9.4 17.9 10.2 10.1 16.1 4.8 10.9 40.4 11.3 9.3 8.2 16.8 5.8 6.5 8.5 10.8 6.5 11.4 13.0 8.7 3.7 4.7 11.2 4.6 11.7 12.2 4.8 17.3 33.6 3.9 2.8 12.2 10.2 20.0 38.0 16.8 17.7 17.8 19.8 5.6 3.8 8.0 19.9 23.8 6.6 5.1 17.9 7.3 2.3 5.1 5.6 10.5 8.4 3.0 4.6 7.3 7.1 7.6 6.0 1.7 3.5 3.9 7.3 6.5 1.4 2.6 5.1 9.1 1.4 3.6 1.4 9.7 19.0 3.4 8.0 9.1 4.0 8.2 8.7 1.4 1.2 8.4 7.7 4.2 4.2 8.8 6.9 4.9 7.0 2.8 7.0 11.2 3.7 6.8 12.2 4.6 6.9 3.7 6.0 6.4 4.7 2.9 11.3 6.8 2.2 11.7 4.0 3.1 2.3 4.8 7.0 8.5 5.3 6.6 6.0 6.2 7.7 7.3 9.1 6.5 B4GALT6 beta4GalT-VI ENSG00000118276 "Beta-1,4-galactosyltransferase 6" Q9UBX8 18 31622247-31685836 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.3" "Cell line enhanced" "Detected in many" "REH: 18.1;WM-115: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 3.8" "Group enriched" "Detected in many" 5 "NK-cells: 3.8;T-cells: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020701, HPA058284" Approved "Intracellular and membrane" "CAB020701: , HPA058284: " "unprognostic (3.79e-1)" "unprognostic (4.52e-1)" "unprognostic (6.54e-3)" "unprognostic (2.23e-4)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.31e-2)" "unprognostic (4.50e-2)" "unprognostic (5.18e-1)" "unprognostic (1.13e-1)" "prognostic favourable (5.65e-4)" "unprognostic (2.77e-1)" "prognostic favourable (6.40e-5)" "unprognostic (5.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.10e-2)" "unprognostic (4.00e-1)" 3.6 13.8 7.8 2.8 16.0 4.4 2.1 20.6 22.3 2.2 3.5 2.6 0.0 7.7 2.5 2.2 4.8 2.5 7.2 3.8 10.7 7.9 3.7 2.7 1.8 1.2 6.1 10.0 4.3 2.1 7.3 14.8 2.7 16.3 5.8 3.6 13.2 4.6 4.4 3.3 2.2 9.7 1.7 3.1 1.5 3.4 5.4 2.3 5.0 2.1 1.5 1.0 3.6 2.1 0.0 0.5 0.0 0.4 3.8 1.1 0.3 2.3 5.3 9.5 5.3 0.1 0.2 3.5 0.7 0.0 0.1 0.0 9.8 2.0 3.6 4.4 0.9 0.9 5.0 4.2 0.6 14.3 4.4 4.8 0.5 0.2 1.1 8.6 0.8 1.0 0.9 1.4 3.0 5.2 0.7 0.0 0.0 1.4 9.6 0.6 4.1 2.9 18.1 1.6 0.0 1.1 4.8 5.1 7.9 3.4 0.6 6.2 0.6 2.6 5.2 10.8 2.2 0.0 5.8 3.6 0.2 7.5 4.4 7.9 50.1 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.1 0.9 0.5 0.0 0.0 1.1 0.0 3.8 0.4 0.0 0.0 0.3 7.8 16.0 20.6 22.3 10.7 7.9 6.1 10.0 16.3 2.3 B4GALT7 "beta4Gal-T7, XGALT-1" ENSG00000027847 "Beta-1,4-galactosyltransferase 7" Q9UBV7 5 177600100-177610347 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation, Dwarfism, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042330 Supported "HPA042330: AB_10796576" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (3.12e-1)" "unprognostic (5.97e-2)" "prognostic unfavourable (2.29e-4)" "unprognostic (9.53e-2)" "unprognostic (4.19e-3)" "unprognostic (3.86e-2)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-3)" "unprognostic (2.00e-2)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (4.44e-2)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" 13.8 33.0 16.0 20.4 14.3 20.7 19.1 10.6 19.6 13.3 12.4 14.9 20.4 16.1 15.5 15.9 11.7 13.3 20.3 17.3 13.7 18.0 16.2 21.3 12.0 21.5 15.1 17.9 16.9 37.0 15.5 23.9 15.3 14.3 16.4 11.7 14.7 22.4 20.9 14.4 12.9 13.7 12.2 10.8 16.3 16.2 16.1 11.7 10.4 16.7 9.8 18.6 13.0 10.2 15.8 16.3 11.2 16.1 8.5 12.5 9.0 8.5 15.1 6.4 15.9 12.7 9.6 28.7 13.3 14.1 12.1 13.9 14.3 13.6 11.0 24.6 13.5 10.2 4.3 28.5 5.3 36.7 11.5 5.8 11.8 9.9 18.4 6.0 10.1 14.6 10.1 13.0 10.6 13.4 5.0 10.6 12.3 19.9 5.0 7.3 6.2 22.3 10.4 4.6 12.0 9.2 13.0 5.6 6.5 6.6 13.4 11.7 8.6 7.0 10.3 15.5 8.9 10.1 13.1 13.3 6.1 7.8 13.1 14.4 14.0 11.2 14.6 7.8 12.5 16.1 11.3 12.8 11.6 11.0 16.3 15.8 10.5 10.3 1.0 8.5 15.3 12.8 7.5 9.0 16.0 14.3 10.6 19.6 13.7 18.0 15.1 17.9 14.3 11.7 BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101360417-101383519 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 128.4" "Cell line enhanced" "Detected in some" "A549: 6.1;CACO-2: 3.4;Hep G2: 2.4" "Cancer enriched" "Detected in many" 42 "liver cancer: 181.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Uncertain Vesicles 470000 Vesicles "HPA021251: AB_1845247, HPA021330: " "unprognostic (2.53e-2)" "unprognostic (1.81e-1)" "unprognostic (9.97e-2)" "unprognostic (9.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.68e-2)" "prognostic favourable (4.97e-4)" "unprognostic (2.14e-2)" "unprognostic (6.19e-2)" "unprognostic (4.43e-4)" "unprognostic (3.65e-1)" "unprognostic (2.15e-1)" "prognostic unfavourable (4.24e-7)" "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.8 0.0 0.1 0.1 0.2 128.4 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.2 0.0 0.7 0.1 0.1 6.1 0.4 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.3 3.4 0.1 0.6 0.2 0.0 0.3 0.1 0.2 0.5 0.3 0.1 0.5 0.2 2.4 0.0 0.9 0.3 0.0 1.0 0.1 0.0 0.0 0.7 0.4 0.5 0.1 0.2 0.3 1.0 0.7 0.2 1.1 0.2 0.6 0.2 0.3 0.4 0.4 0.2 0.5 0.0 0.2 0.1 0.6 0.6 0.2 0.4 0.4 0.6 0.5 0.5 0.2 0.6 0.3 0.2 0.0 0.7 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 BACE1 BACE ENSG00000186318 "Beta-secretase 1" P56817 11 117285207-117316259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "brain: 53.0;pancreas: 161.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016358 Approved Supported "Plasma membrane" "Plasma membrane" "CAB016358: AB_626716" "unprognostic (7.96e-3)" "unprognostic (8.05e-2)" "unprognostic (3.55e-2)" "unprognostic (3.05e-3)" "unprognostic (8.94e-2)" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.60e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (8.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (6.76e-4)" 6.5 7.1 12.1 3.8 18.8 2.2 5.5 9.6 22.4 9.8 4.6 42.5 2.7 3.4 9.3 5.6 7.6 8.6 9.1 5.9 16.9 12.4 6.8 12.1 7.3 2.8 28.8 15.0 11.4 161.1 12.8 4.2 6.3 26.4 6.5 4.7 6.9 5.3 9.9 6.2 7.2 3.6 11.7 53.0 5.7 4.9 4.1 21.4 0.0 6.3 2.3 2.8 6.7 5.5 4.0 2.2 0.7 3.2 2.2 6.7 1.1 3.9 4.6 9.6 14.7 32.0 34.5 0.4 21.2 18.5 10.3 8.4 3.6 6.2 0.7 5.2 38.3 6.9 10.3 6.1 8.5 2.3 5.5 2.3 7.9 4.3 15.8 0.8 0.5 29.9 9.5 13.2 12.8 8.9 0.8 0.4 18.9 14.2 0.6 1.9 6.2 10.4 1.8 4.3 0.8 4.4 2.2 12.5 14.0 7.9 1.0 2.3 10.2 2.7 12.1 18.6 2.0 19.4 6.8 0.3 0.3 0.4 8.7 1.2 13.0 0.6 2.0 0.7 2.0 3.2 5.2 4.0 6.7 5.3 2.2 1.8 3.1 2.7 0.0 2.2 1.3 1.3 6.3 1.1 12.1 18.8 9.6 21.7 16.9 12.4 28.8 15.0 26.4 21.4 BACE2 "AEPLC, ALP56, CEAP1, DRAP" ENSG00000182240 "Beta-site APP-cleaving enzyme 2" Q9Y5Z0 21 41167801-41282518 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 16.9;SK-BR-3: 28.6;SK-MEL-30: 22.2;WM-115: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 4.8;eosinophil: 8.4" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.4" "Low region specificity" "Detected in all" HPA035416 Approved "Intracellular and membrane" "HPA035416: " "unprognostic (1.71e-2)" "prognostic unfavourable (1.11e-4)" "unprognostic (5.23e-2)" "unprognostic (8.12e-3)" "prognostic unfavourable (5.86e-4)" "unprognostic (1.52e-2)" "unprognostic (2.58e-2)" "unprognostic (2.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.49e-1)" "unprognostic (3.46e-2)" "unprognostic (8.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (5.83e-2)" 16.1 2.5 1.4 5.9 1.6 0.9 13.8 0.9 2.0 9.0 11.0 3.4 5.6 5.1 10.3 10.7 13.0 6.8 38.9 7.2 1.7 1.6 11.4 4.4 4.9 21.6 2.7 0.5 8.4 29.0 3.3 2.2 17.2 4.4 22.7 7.4 8.7 28.3 4.4 10.6 5.5 5.4 7.8 5.9 7.0 31.6 5.1 1.4 1.3 9.9 7.6 14.3 11.8 33.6 1.0 0.0 8.4 0.0 0.3 0.0 0.0 16.9 1.6 5.7 0.0 1.5 1.6 0.0 4.2 0.0 2.9 2.5 0.0 6.5 0.0 8.0 5.3 5.3 0.0 10.0 1.0 0.0 8.4 3.3 1.9 0.0 0.7 0.0 8.0 4.1 1.9 0.3 2.1 8.4 0.0 0.0 4.0 3.1 1.9 0.0 4.4 8.7 0.6 0.0 6.3 5.2 1.1 0.2 0.0 0.3 28.6 22.2 8.0 0.0 8.3 4.7 3.4 3.8 6.0 0.0 0.0 0.0 9.8 0.0 20.3 4.8 0.0 8.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 1.6 0.9 2.0 1.7 1.6 2.7 0.5 4.4 1.4 BAP1 "hucep-6, KIAA0272, UCHL2" ENSG00000163930 "BRCA1 associated protein 1" Q92560 3 52401013-52410350 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004322, HPA028814, HPA028815, HPA055560" Approved Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: , HPA055560: " "unprognostic (1.52e-1)" "unprognostic (7.96e-2)" "unprognostic (1.96e-2)" "unprognostic (6.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-2)" "unprognostic (9.41e-3)" "unprognostic (8.53e-3)" "unprognostic (1.33e-1)" "unprognostic (3.15e-1)" "unprognostic (4.64e-3)" "unprognostic (3.30e-3)" "prognostic favourable (3.29e-7)" "unprognostic (6.37e-2)" "unprognostic (1.91e-1)" "unprognostic (5.54e-2)" "unprognostic (2.92e-1)" 13.8 17.6 35.6 14.7 33.3 37.3 13.5 21.8 50.4 12.5 17.0 16.3 11.5 12.4 14.7 14.6 21.2 12.1 15.7 16.4 41.5 15.5 16.6 19.0 14.9 15.2 19.4 27.6 16.9 16.3 30.0 11.1 14.8 19.6 14.4 14.9 15.6 17.9 14.6 24.8 40.5 13.9 14.5 10.0 16.1 13.3 37.3 14.7 18.6 15.3 12.9 16.0 14.1 11.7 5.5 8.4 11.3 5.0 3.0 8.5 3.9 15.3 17.5 21.2 18.0 20.5 13.2 23.9 15.2 19.7 24.7 19.2 21.1 14.4 22.0 7.6 21.2 12.5 22.3 24.5 15.8 21.8 21.1 27.3 37.0 21.8 19.1 25.6 24.3 19.7 32.9 27.3 14.7 19.7 23.3 19.5 18.6 13.3 30.3 35.1 23.9 21.3 13.1 17.2 21.7 15.2 24.9 8.1 26.1 18.7 5.4 22.2 15.3 35.4 21.1 22.4 20.6 26.8 28.2 29.6 38.9 31.5 24.4 27.0 26.4 3.4 5.0 7.4 8.5 3.9 4.0 5.0 6.8 6.9 3.3 5.5 4.9 6.4 11.3 3.0 3.1 8.4 6.0 3.9 35.6 33.3 21.8 50.4 41.5 15.5 19.4 27.6 19.6 14.7 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" "Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: , HPA044864: " "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 4.4 1.9 3.2 11.8 4.8 16.1 4.9 1.2 5.8 7.3 5.4 5.4 3.6 3.7 6.8 5.0 10.0 4.1 3.9 3.6 3.4 2.8 2.2 2.1 5.3 8.2 5.1 1.9 5.8 3.7 3.6 6.3 3.8 4.5 5.7 6.1 1.9 4.7 6.5 12.4 16.3 4.5 7.5 5.3 4.7 3.8 9.5 3.9 25.8 4.0 8.0 9.9 8.3 7.8 9.7 6.6 6.0 3.4 6.1 16.0 2.0 7.7 4.3 11.7 6.0 1.6 2.0 8.0 9.4 5.5 9.3 10.7 5.4 7.7 8.3 4.5 3.9 8.5 8.4 5.5 13.3 6.6 4.4 8.3 7.9 5.7 0.6 9.2 8.4 2.7 0.8 8.2 4.5 3.1 4.6 23.5 8.9 6.4 16.5 9.6 9.2 2.2 14.3 11.8 7.5 2.7 6.5 3.7 5.9 8.6 9.9 3.4 10.2 9.2 2.7 12.0 8.4 7.0 8.5 7.1 7.9 16.9 4.8 7.0 8.0 2.9 1.7 6.0 4.8 3.4 3.1 8.9 5.3 5.2 3.0 9.7 2.5 3.6 0.5 6.1 2.9 6.6 16.0 2.0 3.2 4.8 1.2 5.8 3.4 2.8 5.1 1.9 4.5 3.9 BAZ1B "WBSCR10, WBSCR9, WSTF" ENSG00000009954 "Bromodomain adjacent to zinc finger domain 1B" Q9UIG0 7 73440398-73522278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037081, CAB037158, HPA067010" Supported Supported "Nuclear bodies" "Nuclear bodies" "CAB037081: AB_477637, CAB037158: AB_477636, HPA067010: " "unprognostic (1.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (2.06e-2)" "unprognostic (1.37e-1)" "unprognostic (5.72e-2)" "unprognostic (1.10e-3)" "unprognostic (1.89e-1)" "unprognostic (1.09e-1)" "unprognostic (2.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.12e-1)" "unprognostic (7.13e-2)" "unprognostic (1.03e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 23.3 22.3 21.4 26.4 23.9 20.7 24.6 32.4 23.4 24.6 24.2 21.1 34.1 15.3 26.3 19.8 18.1 20.6 16.5 19.8 22.4 21.4 17.1 23.4 19.4 24.7 29.3 19.4 31.8 20.2 34.9 27.0 23.1 22.3 23.1 20.5 16.4 18.0 30.8 28.9 14.6 19.2 28.7 22.9 22.2 18.8 16.2 27.3 46.5 23.5 17.9 27.7 24.7 24.4 5.3 6.2 6.1 3.1 5.6 6.3 1.7 20.6 21.3 29.4 32.8 15.2 16.3 9.8 20.1 15.5 19.4 20.5 17.3 15.7 39.1 4.7 17.9 14.6 35.7 13.4 29.3 22.0 18.1 23.3 25.3 14.9 17.0 35.1 19.7 11.6 13.1 23.9 29.5 15.4 40.5 24.6 21.7 19.6 35.9 16.2 19.0 16.0 36.6 25.8 26.0 11.0 16.3 29.5 25.2 28.7 32.1 16.8 19.7 17.6 18.0 33.7 19.4 20.2 34.2 14.3 22.7 67.1 19.1 33.3 30.5 6.1 3.1 1.9 6.3 2.2 5.5 2.5 4.8 4.6 2.1 5.3 3.8 4.1 2.2 5.6 1.7 6.2 4.7 1.7 21.4 23.9 32.4 23.4 22.4 21.4 29.3 19.4 22.3 27.3 BBOX1 "BBH, BBOX, G-BBH, gamma-BBH" ENSG00000129151 "Gamma-butyrobetaine hydroxylase 1" O75936 11 27040725-27127809 "Enzymes, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 139.4;liver: 39.3" "Group enriched" "Detected in some" 5 "hTCEpi: 15.9;RPTEC TERT1: 9.8" "Group enriched" "Detected in many" 6 "glioma: 23.7;renal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007600, HPA027823" Enhanced Approved Uncertain "Vesicles,Actin filaments" 25000 Vesicles "Actin filaments" "HPA007600: AB_1845284, HPA027823: AB_10602394" "unprognostic (9.96e-3)" "unprognostic (1.80e-2)" "unprognostic (8.17e-2)" "prognostic unfavourable (6.65e-4)" "unprognostic (7.03e-2)" "unprognostic (6.66e-2)" "unprognostic (7.05e-3)" "unprognostic (1.13e-2)" "unprognostic (3.03e-1)" "unprognostic (6.89e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "prognostic favourable (1.45e-5)" "unprognostic (1.71e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-1)" "unprognostic (1.73e-3)" 0.9 0.5 9.2 0.5 7.1 0.5 8.2 3.9 7.5 1.5 0.6 4.9 0.1 0.5 0.6 3.6 5.7 3.8 3.6 0.5 7.9 6.3 139.4 39.3 0.6 0.6 10.9 4.3 0.5 0.8 0.5 8.3 1.3 9.2 0.7 0.5 0.0 2.2 2.0 0.6 16.4 0.5 0.5 7.1 0.5 0.6 0.6 5.8 0.0 8.9 1.6 0.7 0.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.0 15.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.5 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 7.1 3.9 7.5 7.9 6.3 10.9 4.3 9.2 5.8 BCAT1 BCT1 ENSG00000060982 "Branched chain amino acid transaminase 1" P54687 12 24810022-24949459 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 52.7" "Cell line enhanced" "Detected in many" "HDLM-2: 51.1;NTERA-2: 58.7;RH-30: 64.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 14.7" "Group enriched" "Detected in many" 9 "dendritic cells: 5.4;monocytes: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048592 Uncertain 85000 "HPA048592: " "unprognostic (1.90e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (3.55e-4)" "unprognostic (3.05e-5)" "unprognostic (9.49e-3)" "unprognostic (4.22e-2)" "unprognostic (4.77e-3)" "unprognostic (1.97e-3)" "unprognostic (4.06e-1)" "prognostic unfavourable (1.38e-4)" "prognostic unfavourable (4.95e-4)" "unprognostic (5.44e-2)" "unprognostic (7.55e-2)" "prognostic unfavourable (8.54e-4)" 12.5 6.1 5.2 6.9 5.7 2.6 6.3 1.3 7.8 4.3 3.0 2.6 0.0 1.4 8.6 3.9 2.9 7.8 4.7 2.4 4.7 7.9 1.8 1.8 13.8 7.4 11.3 2.9 8.3 52.7 1.1 19.1 14.0 18.5 2.0 3.1 12.3 4.4 1.4 1.3 1.2 3.8 5.9 6.3 2.4 2.4 7.3 2.0 7.1 1.7 0.7 5.3 4.3 6.3 1.1 5.4 1.0 14.7 0.0 0.2 0.8 5.9 2.4 22.1 0.0 6.4 12.5 11.4 12.2 8.2 6.9 11.6 13.4 16.9 22.2 0.0 20.3 2.4 15.8 0.1 18.6 51.1 3.1 18.0 0.4 7.2 23.2 20.4 6.6 16.2 0.4 17.6 3.7 23.3 17.3 0.2 5.8 0.1 12.8 5.7 58.7 1.6 0.0 64.1 0.2 0.0 2.1 0.0 12.1 0.0 0.0 0.1 0.0 8.8 30.6 4.1 15.5 16.5 11.4 2.7 2.6 30.9 14.5 12.3 0.0 0.0 2.1 0.0 0.0 3.4 0.1 1.1 0.0 0.1 5.4 0.0 0.0 0.0 1.0 0.0 14.7 3.3 0.2 0.8 5.2 5.7 1.3 7.4 4.7 7.9 11.3 2.9 18.5 2.0 BCAT2 "BCAM, BCT2" ENSG00000105552 "Branched chain amino acid transaminase 2" O15382 19 48795062-48811029 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054091 Enhanced Supported Mitochondria 3400000 Mitochondria "HPA054091: " "unprognostic (2.58e-2)" "unprognostic (1.23e-2)" "unprognostic (2.16e-1)" "unprognostic (2.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.97e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (2.98e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (1.06e-1)" "prognostic favourable (3.68e-5)" "unprognostic (1.87e-3)" "unprognostic (1.35e-1)" "unprognostic (2.42e-1)" "unprognostic (7.50e-3)" 11.8 34.1 6.7 10.9 7.7 3.8 15.0 15.0 10.7 11.9 16.7 11.3 15.8 10.2 12.9 9.8 24.6 11.9 15.2 25.1 6.8 6.9 22.6 8.0 19.9 16.3 9.8 7.8 22.3 42.6 9.0 12.3 27.5 22.0 16.8 12.1 6.3 24.7 17.2 23.3 9.8 10.3 17.5 7.6 10.9 22.8 15.9 10.7 12.5 19.1 23.3 16.7 29.2 12.2 15.0 18.2 1.8 9.8 8.8 15.4 7.1 17.4 21.0 5.6 11.8 23.3 7.9 9.9 7.7 3.9 9.5 9.3 21.0 10.7 20.5 8.9 6.9 8.3 8.6 13.5 4.8 12.8 21.7 7.5 9.4 1.3 22.6 10.1 7.1 11.4 8.6 7.1 10.3 13.2 9.6 12.7 3.4 20.8 13.8 10.8 4.9 10.2 21.1 9.6 22.6 9.0 72.2 30.1 8.6 11.8 19.4 5.7 12.3 5.0 7.3 9.3 9.0 10.9 9.6 11.9 15.8 9.8 5.0 15.8 6.0 0.0 8.7 1.8 9.7 9.8 13.6 15.0 11.7 12.4 16.1 12.8 10.8 9.6 0.4 8.8 3.7 18.2 15.4 7.1 6.7 7.7 15.0 10.7 6.8 6.9 9.8 7.8 22.0 10.7 BCHE "CHE1, CHE2, E1" ENSG00000114200 Butyrylcholinesterase P06276 3 165772904-165837472 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 145.4" "Cell line enriched" "Detected in some" 9 "Karpas-707: 128.6" "Group enriched" "Detected in many" 6 "glioma: 24.0;liver cancer: 13.7;melanoma: 18.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001560 Approved "Secreted to blood" 13000000000 "HPA001560: AB_1078271" "unprognostic (4.74e-2)" "unprognostic (2.00e-1)" "unprognostic (9.21e-4)" "unprognostic (8.19e-8)" "unprognostic (2.66e-2)" "prognostic unfavourable (1.06e-4)" "unprognostic (1.44e-1)" "unprognostic (5.04e-2)" "unprognostic (6.15e-2)" "unprognostic (9.59e-2)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" "unprognostic (3.18e-3)" "unprognostic (4.46e-5)" "unprognostic (2.17e-2)" "unprognostic (5.92e-2)" "unprognostic (4.26e-4)" 14.0 3.9 6.7 6.2 4.3 0.4 1.9 3.6 9.1 24.4 15.5 4.7 8.3 1.8 20.2 13.4 20.0 18.0 2.2 7.8 6.1 4.4 2.8 145.4 3.7 0.7 5.5 2.7 10.3 1.1 0.4 1.2 0.5 4.7 4.7 5.3 0.7 1.0 10.5 1.1 2.8 6.4 13.9 3.4 3.7 1.9 1.8 6.1 1.0 0.8 0.4 0.5 9.7 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 14.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.2 0.0 0.0 0.0 5.3 0.0 0.0 0.9 0.0 0.9 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 4.1 0.2 0.0 1.3 0.6 0.0 128.6 0.0 0.0 0.0 0.0 0.3 0.1 0.0 4.7 10.7 0.1 0.0 0.0 0.1 0.0 0.0 7.4 5.7 0.0 0.0 3.2 0.0 0.0 1.3 0.5 0.0 0.2 1.3 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 4.3 3.6 4.3 6.1 4.4 5.5 2.7 4.7 6.1 BCKDHA "MSU, OVD1A" ENSG00000248098 "Branched chain keto acid dehydrogenase E1, alpha polypeptide" P12694 19 41397460-41425005 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036640 Supported "HPA036640: AB_10671964" "unprognostic (4.50e-2)" "unprognostic (6.85e-2)" "unprognostic (1.14e-1)" "unprognostic (8.58e-3)" "unprognostic (1.26e-2)" "prognostic favourable (9.37e-4)" "unprognostic (2.41e-2)" "unprognostic (8.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-2)" "unprognostic (1.12e-2)" "unprognostic (1.53e-1)" "prognostic favourable (5.33e-10)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "prognostic unfavourable (3.27e-5)" "unprognostic (9.66e-2)" 18.4 36.1 11.5 9.2 14.9 11.4 12.9 9.3 19.3 12.5 11.2 16.6 25.0 11.2 11.0 11.2 31.0 15.0 12.4 41.1 10.8 9.5 23.4 47.6 12.3 17.0 16.0 17.6 13.8 28.2 15.7 12.6 13.4 12.7 12.6 8.8 15.0 23.1 31.1 61.7 15.6 10.4 10.8 11.2 13.2 22.0 21.2 13.5 15.8 21.8 25.3 15.9 14.0 15.1 16.5 45.9 17.6 38.0 25.9 19.7 27.1 14.2 26.2 2.3 14.0 6.6 4.0 6.0 3.5 6.7 6.9 8.8 6.0 9.9 11.5 7.9 3.7 5.7 4.4 7.1 3.6 12.0 12.6 8.0 13.7 5.6 14.1 8.4 5.9 7.3 10.2 4.6 10.2 13.3 8.0 21.8 6.2 12.9 7.2 5.1 3.9 6.5 8.7 7.8 27.4 9.7 6.7 10.2 12.2 12.4 28.2 8.6 14.5 22.6 10.0 7.4 7.6 4.3 7.5 48.8 19.7 11.3 26.8 15.7 8.6 13.5 36.9 17.6 15.8 38.0 18.2 16.5 15.9 16.1 45.9 16.4 13.4 15.3 10.9 25.9 26.1 17.6 19.7 27.1 11.5 14.9 9.3 19.3 10.8 9.5 16.0 17.6 12.7 13.5 BCKDHB ENSG00000083123 "Branched chain keto acid dehydrogenase E1 subunit beta" P21953 6 80106647-80346270 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031580, HPA031956" Approved Supported Nucleoli,Mitochondria "Intracellular and membrane" Mitochondria Nucleoli "HPA031580: AB_10696054, HPA031956: " "unprognostic (4.23e-1)" "unprognostic (1.61e-1)" "unprognostic (9.50e-3)" "unprognostic (9.37e-3)" "unprognostic (1.66e-1)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (2.30e-2)" "unprognostic (1.94e-1)" "unprognostic (7.32e-3)" "unprognostic (2.67e-1)" "unprognostic (4.65e-2)" "prognostic favourable (5.54e-9)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (1.49e-2)" 13.9 12.0 9.9 9.0 12.2 5.8 18.1 9.5 14.3 10.2 17.3 22.7 9.4 9.1 11.6 7.7 10.2 10.9 7.4 14.7 11.9 7.6 24.7 58.6 6.4 8.1 11.3 11.2 13.9 12.1 13.7 15.5 5.5 14.1 13.1 16.5 11.7 30.5 10.3 8.2 8.6 11.8 11.5 16.7 5.3 15.0 10.0 12.4 11.2 12.5 7.9 7.7 14.0 8.2 9.1 10.3 2.6 4.3 13.4 15.7 5.2 6.9 2.6 9.9 13.2 10.0 8.8 7.9 4.9 10.3 8.1 11.2 4.2 9.6 19.7 5.3 11.8 7.0 5.5 6.5 11.5 24.5 8.1 9.7 6.8 5.7 11.2 13.9 4.4 8.4 6.8 5.6 7.0 9.7 8.2 17.7 18.2 3.8 5.0 8.1 7.3 3.4 12.8 30.7 16.8 22.6 10.6 6.6 9.3 8.4 7.0 4.9 9.0 10.7 4.1 4.9 3.4 4.5 6.6 12.6 12.3 6.5 6.0 10.4 7.3 2.6 3.4 0.8 8.5 4.0 11.1 9.1 7.2 7.2 6.6 9.1 9.6 10.0 0.7 13.4 4.3 10.3 15.7 5.2 9.9 12.2 9.5 14.3 11.9 7.6 11.3 11.2 14.1 12.4 BCKDK ENSG00000103507 "Branched chain ketoacid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 26.8;granulocytes: 26.6;monocytes: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria Mitochondria "HPA017995: AB_1845309, HPA056067: " "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (6.94e-2)" "unprognostic (5.20e-2)" "unprognostic (5.39e-2)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (5.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.24e-2)" "unprognostic (2.66e-3)" "unprognostic (4.85e-2)" "unprognostic (3.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" 15.4 29.7 11.9 13.1 15.0 9.4 18.3 18.8 21.3 11.7 14.1 9.6 19.9 11.2 14.8 14.9 14.9 13.8 15.1 39.2 14.2 10.3 21.3 46.5 18.2 32.5 10.7 17.3 15.1 52.4 17.4 8.9 11.4 13.2 14.9 9.9 10.4 33.9 25.7 67.7 21.5 12.2 19.9 15.6 16.0 19.9 11.2 9.3 8.0 11.7 25.9 10.6 15.3 12.0 6.9 26.8 26.6 33.0 6.3 6.8 13.6 18.1 20.4 11.5 17.3 14.2 14.3 12.5 15.8 19.5 24.6 24.1 13.3 12.1 17.0 23.0 19.7 12.6 8.1 27.5 15.9 13.7 25.3 18.4 13.9 24.2 25.1 9.5 16.9 21.0 11.1 21.1 17.6 26.2 9.3 16.1 36.8 30.9 8.8 12.6 9.8 16.5 17.8 16.8 31.3 18.8 12.5 17.8 16.3 12.3 30.3 9.8 18.2 9.2 16.8 18.8 10.9 19.2 13.1 16.8 6.0 6.0 21.3 13.8 17.6 12.2 33.0 23.1 5.7 27.4 5.6 6.9 5.2 4.2 26.8 5.4 4.4 5.0 26.6 6.3 19.3 5.8 6.8 13.6 11.9 15.0 18.8 21.3 14.2 10.3 10.7 17.3 13.2 9.3 BCO1 "BCDO, BCDO1, BCMO, BCMO1, FLJ10730" ENSG00000135697 "Beta-carotene oxygenase 1" Q9HAY6 16 81238448-81291142 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 28.1;retina: 62.0" "Cell line enhanced" "Detected in some" "A549: 12.5;EFO-21: 9.5;HAP1: 3.6;NTERA-2: 5.1;RPTEC TERT1: 9.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA043811 Uncertain "Actin filaments,Centriolar satellite" "Actin filaments, Centriolar satellite" "HPA043811: AB_10962487" "unprognostic (2.78e-1)" "unprognostic (3.88e-3)" "unprognostic (2.61e-1)" "unprognostic (3.32e-1)" "unprognostic (4.05e-2)" "unprognostic (8.01e-4)" "unprognostic (1.65e-1)" "unprognostic (2.99e-2)" "unprognostic (1.58e-3)" "unprognostic (7.26e-2)" "unprognostic (2.97e-2)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.90e-2)" "unprognostic (2.48e-1)" "unprognostic (5.07e-2)" "unprognostic (1.09e-1)" 0.1 0.0 1.3 0.2 1.4 0.0 0.2 0.2 1.6 0.3 28.1 0.3 1.4 11.0 0.7 0.5 0.7 0.6 1.4 0.1 1.7 1.9 4.2 2.5 0.3 0.1 0.8 0.1 2.0 0.4 0.0 1.9 0.1 5.9 1.3 3.6 62.0 1.3 2.8 0.6 0.3 16.9 0.4 0.4 0.1 2.3 0.2 0.3 0.3 0.2 0.5 0.1 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.4 2.5 0.0 9.5 0.0 0.1 3.6 0.0 0.0 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 5.1 0.0 0.0 0.0 0.0 9.6 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.4 0.2 1.6 1.7 1.9 0.8 0.1 5.9 0.3 BCO2 "B-DIOX-II, BCDO2, FLJ34464" ENSG00000197580 "Beta-carotene oxygenase 2" Q9BYV7 11 112175467-112224699 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 28.9;liver: 44.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.4;HHSteC: 16.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "NK-cell: 2.8" "Lineage enriched" "Detected in single" 5 "NK-cells: 2.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061542 Supported "HPA061542: " "unprognostic (2.92e-1)" "unprognostic (1.89e-1)" "unprognostic (3.76e-2)" "unprognostic (1.40e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-2)" "unprognostic (7.60e-3)" "unprognostic (1.88e-1)" "unprognostic (3.18e-2)" "unprognostic (6.40e-2)" "unprognostic (2.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.36e-4)" "unprognostic (2.31e-2)" "unprognostic (9.86e-2)" "unprognostic (1.07e-2)" "unprognostic (1.34e-1)" 2.3 14.7 4.0 0.9 6.8 0.8 1.3 1.9 4.6 1.2 1.5 5.9 0.3 1.1 2.0 2.8 2.1 9.5 6.0 28.9 3.5 3.9 1.6 44.0 1.8 0.9 10.5 2.6 1.5 1.3 0.8 16.3 3.9 9.5 1.3 1.1 12.4 1.1 1.5 17.3 1.5 1.6 4.4 11.0 1.0 1.1 2.4 9.8 0.0 1.9 1.0 1.3 1.3 2.7 0.3 0.5 0.3 0.6 2.8 0.2 0.0 0.1 1.3 0.6 0.7 0.5 0.5 0.0 0.4 0.3 0.1 0.7 0.0 7.4 0.5 0.6 0.8 1.6 0.0 0.3 0.4 0.1 0.2 1.0 0.7 0.5 16.0 0.5 0.3 0.1 3.0 0.2 0.4 0.1 0.2 0.4 0.1 0.1 0.6 1.6 0.1 0.2 0.4 0.2 0.2 0.2 0.3 0.6 0.3 0.6 0.3 0.0 0.4 0.3 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.0 3.3 0.4 0.1 0.6 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.5 0.2 0.0 0.0 0.3 2.8 0.2 0.2 0.0 0.0 4.0 6.8 1.9 4.6 3.5 3.9 10.5 2.6 9.5 9.8 BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR, RhoGEF and GTPase activating protein" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favourable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" 14.5 8.4 24.0 9.1 41.2 26.7 10.5 14.2 26.5 13.6 9.7 10.3 10.6 8.7 9.2 13.9 19.3 10.8 8.3 7.8 20.9 13.0 16.3 8.3 11.3 10.9 16.0 15.6 8.8 12.9 14.5 14.9 15.7 14.2 7.0 6.8 8.3 15.5 9.7 3.4 12.8 8.7 9.0 9.5 9.1 14.0 9.6 15.4 11.8 16.6 5.5 9.2 9.2 8.8 1.5 0.8 1.2 1.0 2.8 6.6 2.5 18.6 8.1 12.4 12.7 7.4 5.1 18.8 6.8 6.3 6.3 5.1 14.1 7.5 13.0 12.6 5.7 19.2 1.3 18.8 1.8 24.9 12.9 11.4 11.1 11.2 9.7 10.5 6.0 4.3 12.7 9.4 8.2 21.8 43.5 6.1 2.8 12.3 9.8 8.2 10.5 7.9 12.9 5.0 8.6 9.7 11.8 11.4 10.8 12.4 10.7 5.1 6.7 8.6 24.6 3.8 0.4 6.1 5.5 1.4 5.6 4.6 9.7 8.0 5.8 0.0 1.0 0.0 6.6 0.4 2.3 1.4 3.3 3.3 0.8 1.5 2.6 3.6 1.2 2.8 1.0 0.8 1.6 2.5 24.0 41.2 14.2 24.9 20.9 13.0 16.0 15.6 14.2 15.4 BDH1 "BDH, SDR9C1" ENSG00000161267 "3-hydroxybutyrate dehydrogenase 1" Q02338 3 197509783-197573323 "Candidate cardiovascular disease genes, Enzymes, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 156.0" "Cell line enhanced" "Detected in many" "U-937: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030947, HPA058709" Enhanced Enhanced Mitochondria Mitochondria "HPA030947: AB_10669548, HPA058709: " "unprognostic (2.72e-2)" "prognostic favourable (1.09e-4)" "unprognostic (1.13e-1)" "unprognostic (3.93e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic favourable (9.86e-7)" "unprognostic (2.08e-1)" "unprognostic (3.85e-2)" "unprognostic (4.53e-2)" "unprognostic (5.17e-3)" "unprognostic (5.85e-3)" "prognostic favourable (7.12e-8)" "unprognostic (5.62e-2)" "unprognostic (1.74e-1)" "unprognostic (6.22e-2)" "unprognostic (1.02e-1)" 3.5 2.8 6.6 5.2 11.2 4.7 4.6 18.1 13.8 4.0 13.9 4.6 6.3 9.6 2.1 3.6 12.9 5.5 6.1 19.6 6.3 5.8 6.0 156.0 2.0 4.2 5.9 9.1 3.0 2.8 5.8 3.6 1.4 7.7 4.5 11.1 6.2 8.6 4.4 7.3 8.0 13.7 2.4 3.5 2.3 4.7 1.8 3.6 5.4 5.2 11.3 7.4 3.6 3.6 6.1 4.6 2.9 1.6 4.7 9.9 4.0 10.5 1.4 0.6 5.4 0.9 0.0 0.0 1.2 1.0 5.5 3.1 9.5 3.5 0.0 15.7 0.3 4.9 4.8 2.5 2.1 0.1 0.0 5.6 3.6 3.2 4.0 12.4 5.9 1.6 3.0 2.1 4.6 1.3 0.0 4.2 0.1 18.8 9.5 8.4 4.1 1.9 9.1 2.0 14.4 5.8 4.8 10.0 4.3 3.8 0.5 2.0 12.7 10.4 0.1 0.3 1.8 0.0 9.9 4.9 9.2 0.1 0.3 35.3 0.7 2.9 1.6 0.6 5.9 0.2 8.2 6.1 6.5 5.3 4.2 5.5 9.9 5.9 0.0 4.7 0.3 4.6 4.2 4.0 6.6 11.2 18.1 13.8 6.3 5.8 5.9 9.1 7.7 3.6 BDH2 "DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308" ENSG00000164039 "3-hydroxybutyrate dehydrogenase 2" Q9BUT1 4 103079435-103099883 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 139.1" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036028, HPA036029" Enhanced Supported Cytosol Cytosol "HPA036028: AB_10670674, HPA036029: " "unprognostic (2.12e-2)" "unprognostic (1.91e-1)" "unprognostic (1.64e-1)" "prognostic favourable (5.21e-4)" "unprognostic (3.92e-1)" "unprognostic (2.28e-1)" "unprognostic (3.82e-2)" "prognostic favourable (1.20e-4)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" "unprognostic (4.37e-1)" "unprognostic (1.95e-1)" "prognostic favourable (4.45e-13)" "unprognostic (2.54e-2)" "unprognostic (1.60e-1)" "prognostic favourable (7.75e-4)" "unprognostic (9.69e-3)" 12.4 33.1 22.6 7.7 26.0 2.8 17.6 9.6 18.5 15.7 18.9 14.8 12.3 36.7 11.6 18.8 10.4 16.6 13.5 14.9 26.6 15.4 139.1 39.3 13.8 6.0 38.2 15.6 26.2 8.3 23.5 14.8 8.1 29.0 13.0 11.2 27.0 10.2 15.2 6.9 7.9 34.8 10.2 29.7 6.7 11.8 7.2 32.4 10.4 25.1 12.0 7.6 11.0 11.8 9.5 7.5 1.4 4.1 11.6 18.5 7.5 2.6 4.5 25.9 7.8 27.1 30.1 3.7 6.2 16.0 5.9 10.0 3.6 10.4 10.8 10.9 9.6 1.3 13.4 10.0 6.9 6.3 8.1 2.1 6.6 11.9 17.4 6.2 3.1 24.1 9.4 10.1 2.3 20.0 6.5 3.4 22.7 1.4 27.8 6.1 7.9 2.1 20.1 25.1 6.3 41.4 5.0 3.5 12.6 11.0 5.9 7.0 5.2 5.1 12.2 7.0 3.7 4.5 2.4 6.5 6.5 11.1 9.3 7.5 5.8 1.4 4.1 0.2 11.9 1.8 12.8 9.5 12.1 11.3 5.8 9.0 14.2 15.3 0.3 11.6 0.3 7.5 18.5 7.5 22.6 26.0 9.6 18.5 26.6 15.4 38.2 15.6 29.0 32.4 BHMT BHMT1 ENSG00000145692 "Betaine--homocysteine S-methyltransferase" Q93088 5 79111779-79132290 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "kidney: 105.9;liver: 216.2" "Cell line enhanced" "Detected in some" "Hep G2: 8.2;NTERA-2: 3.5;SCLC-21H: 2.2" "Cancer enhanced" "Detected in some" "liver cancer: 90.6;renal cancer: 50.4" "Region enhanced" "Detected in single" "hippocampal formation: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038285, HPA058310" Enhanced Supported Cytosol 9200000 Cytosol "HPA038285: AB_10675791, HPA058310: AB_2683675" "unprognostic (2.61e-2)" "unprognostic (4.12e-1)" "unprognostic (4.45e-1)" "unprognostic (4.14e-3)" "unprognostic (5.62e-2)" "unprognostic (4.14e-1)" "prognostic favourable (7.32e-4)" "unprognostic (5.33e-2)" "unprognostic (1.51e-1)" "unprognostic (1.13e-1)" "unprognostic (9.66e-4)" "unprognostic (6.42e-2)" "unprognostic (8.26e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.60e-2)" "unprognostic (2.30e-3)" 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.1 1.5 0.0 105.9 216.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 4.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 8.2 0.0 1.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 3.5 0.0 0.0 1.2 0.0 0.0 0.0 2.2 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.5 0.0 0.0 0.6 0.1 0.0 BHMT2 ENSG00000132840 "Betaine--homocysteine S-methyltransferase 2" Q9H2M3 5 79069717-79089466 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "kidney: 87.9;liver: 122.9" "Cell line enhanced" "Detected in some" "BJ hTERT+: 8.9;Hep G2: 37.2;hTEC/SVTERT24-B: 22.8;U-87 MG: 9.6" "Group enriched" "Detected in many" 14 "liver cancer: 79.6;renal cancer: 52.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044573 Enhanced 1400000 "HPA044573: AB_10795044" "unprognostic (5.03e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-2)" "unprognostic (3.76e-2)" "unprognostic (4.40e-2)" "unprognostic (2.90e-3)" "unprognostic (1.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.87e-2)" "unprognostic (2.45e-3)" "unprognostic (1.41e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-2)" "unprognostic (5.05e-2)" "unprognostic (1.49e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-3)" 9.3 4.4 1.7 0.9 2.0 0.2 8.2 1.1 1.0 1.7 3.4 1.1 2.9 0.6 3.2 10.5 3.5 1.4 2.9 3.3 1.5 1.5 87.9 122.9 0.6 0.4 1.6 1.0 1.9 0.5 0.5 3.2 0.3 3.5 3.0 0.8 8.2 0.8 4.0 2.2 0.4 1.3 10.5 2.2 0.3 2.4 1.4 0.9 0.0 4.6 1.9 0.4 6.4 4.4 0.9 0.5 3.2 0.4 2.4 0.7 0.3 0.0 0.0 0.0 0.0 4.3 3.1 1.4 3.7 8.9 2.1 4.1 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.1 37.2 3.4 0.2 0.0 3.8 0.0 22.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 9.6 0.2 0.0 2.5 0.4 0.7 0.4 0.3 0.5 0.5 0.6 0.4 0.2 0.9 0.6 0.7 3.2 2.4 0.2 0.5 0.4 0.3 1.7 2.0 1.1 1.0 1.5 1.5 1.6 1.0 3.5 0.9 BIRC2 "API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48" ENSG00000110330 "Baculoviral IAP repeat containing 2" Q13490 11 102347211-102378670 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005513, CAB020661" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Nucleoli fibrillar center, Cytosol" Nucleoplasm "CAB020661: , HPA005513: AB_1846746" "unprognostic (1.36e-1)" "unprognostic (3.29e-1)" "unprognostic (9.52e-3)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (7.02e-2)" "unprognostic (2.72e-2)" "unprognostic (1.04e-2)" "unprognostic (1.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.05e-2)" "unprognostic (3.02e-2)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (5.00e-2)" "unprognostic (1.64e-2)" 20.9 25.8 19.1 23.3 24.1 25.9 57.0 20.5 28.5 25.1 22.2 18.4 18.7 19.3 24.6 31.1 18.6 17.0 21.1 39.2 19.1 18.3 24.3 36.8 34.0 47.2 23.3 15.8 21.5 40.8 22.0 27.3 24.3 22.3 19.6 22.2 14.3 21.9 22.1 38.8 17.3 24.4 23.8 26.3 27.6 19.0 19.7 15.5 51.2 18.9 17.3 21.9 22.2 20.2 5.8 12.6 37.5 16.6 12.2 12.0 9.8 9.6 7.2 11.1 8.7 14.1 19.5 7.1 37.5 14.4 21.5 13.1 8.9 24.1 10.6 37.2 17.2 10.7 7.2 9.9 25.9 14.2 3.7 10.7 5.3 10.8 14.4 6.4 6.9 12.4 19.3 12.3 15.8 14.7 9.6 0.0 38.7 3.1 6.8 5.7 5.3 7.0 3.4 14.4 7.1 16.6 11.2 4.6 6.1 13.1 8.0 11.2 12.6 7.8 24.1 45.6 10.3 13.7 24.2 4.4 6.0 7.3 9.8 8.2 33.2 31.7 16.6 37.5 9.1 15.2 7.5 5.8 8.7 8.4 12.6 5.6 11.3 11.3 25.5 12.2 16.3 7.6 12.0 9.8 19.1 24.1 20.5 28.5 19.1 18.3 23.3 15.8 22.3 15.5 BIRC3 "API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49" ENSG00000023445 "Baculoviral IAP repeat containing 3" Q13489 11 102317450-102339403 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 46.0;lymphoid tissue: 46.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 37.5;Daudi: 33.0;HDLM-2: 31.2;hTERT-HME1: 32.8;U-266/70: 22.0;U-266/84: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "memory B-cell: 32.9;naive B-cell: 32.9" "Group enriched" "Detected in many" 10 "B-cells: 32.9;T-cells: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002317 Enhanced Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA002317: AB_1846748" "prognostic favourable (3.60e-4)" "unprognostic (2.89e-1)" "prognostic favourable (9.35e-4)" "unprognostic (3.28e-2)" "prognostic unfavourable (7.28e-4)" "unprognostic (5.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.88e-3)" "unprognostic (9.62e-2)" "unprognostic (1.29e-1)" "prognostic unfavourable (3.03e-4)" "unprognostic (3.21e-1)" "prognostic unfavourable (6.66e-6)" "unprognostic (6.42e-2)" "unprognostic (6.23e-3)" "unprognostic (1.00e-1)" "unprognostic (3.85e-2)" 6.9 3.3 1.4 43.9 2.3 5.1 5.4 0.5 2.0 5.3 13.1 0.5 2.8 6.8 2.9 3.7 8.4 3.9 13.9 6.0 2.2 1.3 10.8 12.5 21.8 46.3 2.8 1.2 3.4 7.0 1.1 14.5 0.9 2.2 8.7 6.2 1.1 9.2 4.7 2.2 5.5 46.0 7.3 3.0 34.9 15.9 3.2 2.7 34.2 3.0 4.1 34.0 12.6 6.2 32.9 0.8 2.0 2.6 2.5 17.1 2.8 6.3 5.1 0.0 0.1 0.1 0.7 0.6 0.5 4.3 0.6 0.7 0.9 37.5 33.0 17.0 0.3 3.6 0.0 0.9 2.1 31.2 0.1 0.1 1.5 0.2 6.5 0.5 0.7 0.7 4.6 2.1 32.8 0.1 0.1 0.0 0.8 0.0 2.2 0.3 0.1 0.2 0.0 0.3 1.6 8.5 3.3 0.0 0.1 0.5 0.5 0.3 1.6 0.3 1.7 7.2 0.7 0.4 6.5 22.0 18.8 11.6 1.3 1.8 0.8 2.0 0.9 0.4 1.4 2.2 2.5 32.9 10.7 3.5 0.8 32.9 7.5 2.2 0.5 2.5 2.6 0.3 17.1 2.8 1.4 2.3 0.5 2.0 2.2 1.3 2.8 1.2 2.2 2.7 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Supported "Golgi apparatus,Vesicles,Mitotic spindle" "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: " "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 15.0 16.7 10.3 20.7 14.4 18.4 16.1 21.9 13.7 16.2 13.0 15.3 15.6 8.7 17.2 13.9 13.2 13.1 11.7 11.4 9.8 7.3 14.1 14.8 12.5 16.1 13.9 11.8 23.6 24.8 32.5 17.4 14.1 14.8 11.3 13.6 11.5 14.7 17.1 20.9 14.9 16.0 12.5 13.3 16.1 13.9 13.0 14.4 23.1 21.5 9.2 17.2 16.2 12.0 3.8 2.8 10.6 2.4 2.3 3.4 0.7 15.1 12.7 11.8 5.1 9.3 13.2 7.1 6.7 9.5 8.3 7.9 8.7 3.6 16.3 5.4 12.6 7.0 16.5 10.0 10.3 13.0 7.5 22.0 8.0 7.2 5.1 20.4 7.8 8.8 4.9 13.0 11.6 12.3 17.8 7.0 7.7 5.8 10.2 4.7 7.9 7.5 10.4 19.0 5.5 6.0 15.6 8.8 13.5 13.3 6.9 6.1 4.6 7.3 19.2 8.7 9.8 5.9 10.2 9.4 13.1 21.8 6.3 10.1 5.7 10.6 1.6 0.9 2.7 1.2 3.4 1.7 2.1 2.3 1.3 3.8 2.3 2.6 2.7 2.3 2.4 2.8 1.6 0.7 10.3 14.4 21.9 13.7 9.8 7.3 13.9 11.8 14.8 14.4 BIRC7 "KIAP, ML-IAP, mliap, RNF50" ENSG00000101197 "Baculoviral IAP repeat containing 7" Q96CA5 20 63235883-63240507 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 14.4;placenta: 13.6;retina: 21.1" "Cell line enriched" "Detected in some" 4 "SK-MEL-30: 62.2" "Cancer enriched" "Detected in many" 10 "melanoma: 73.7" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "naive CD8 T-cell: 2.0" "Lineage enriched" "Detected in single" 9 "T-cells: 2.0" "Not detected" "Not detected" "HPA047850, HPA061283" Enhanced Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA047850: , HPA061283: " "unprognostic (3.60e-1)" "unprognostic (7.94e-2)" "unprognostic (2.70e-2)" "unprognostic (1.78e-3)" "unprognostic (1.15e-1)" "unprognostic (8.11e-2)" "unprognostic (1.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.62e-3)" "unprognostic (1.24e-2)" "unprognostic (6.90e-2)" "unprognostic (2.27e-1)" "unprognostic (8.82e-3)" "unprognostic (1.22e-2)" "unprognostic (4.77e-2)" "unprognostic (2.55e-2)" "unprognostic (4.84e-2)" 1.6 1.3 1.0 0.7 1.0 0.3 0.7 0.1 2.2 3.0 1.3 0.5 0.1 0.4 0.8 14.4 0.3 0.3 0.5 2.8 0.9 1.1 2.6 0.8 2.3 2.2 4.9 1.0 0.2 0.1 0.1 0.6 13.6 1.5 0.4 0.3 21.1 0.8 0.1 0.1 4.9 0.3 0.2 4.3 1.6 0.3 0.4 0.3 0.3 0.3 1.0 0.5 0.4 1.8 0.0 0.0 0.0 0.2 0.0 2.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.1 0.4 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.0 0.0 0.0 0.2 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 62.2 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.0 0.1 2.2 0.9 1.1 4.9 1.0 1.5 0.3 BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564604 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "blood: 47.8;intestine: 23.5;lymphoid tissue: 39.8" "Cell line enhanced" "Detected in some" "Daudi: 43.0;REH: 11.6;RPMI-8226: 14.2;U-698: 21.0;U-87 MG: 8.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 47.8;naive B-cell: 33.9" "Lineage enriched" "Detected in many" 5 "B-cells: 47.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005093, HPA069571" Approved Approved Nucleoplasm Nucleoplasm "CAB005093: AB_2274756, HPA069571: " "unprognostic (6.50e-5)" "unprognostic (4.22e-3)" "unprognostic (5.64e-2)" "unprognostic (1.42e-1)" "unprognostic (3.45e-1)" "unprognostic (5.98e-6)" "unprognostic (1.59e-2)" "unprognostic (8.94e-4)" "unprognostic (1.02e-3)" "unprognostic (9.83e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (9.05e-6)" "unprognostic (5.62e-2)" "unprognostic (5.43e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" 0.5 0.2 0.1 32.3 0.1 1.7 0.2 0.1 0.1 0.1 1.2 0.0 0.0 0.3 0.1 0.0 1.9 0.2 0.4 0.3 0.1 0.1 1.3 0.5 0.6 27.6 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.4 0.3 2.4 0.0 0.1 0.1 23.5 0.0 0.1 31.9 1.4 0.2 0.0 3.9 0.7 0.4 39.8 2.5 0.4 47.8 4.3 0.1 0.0 0.0 9.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.6 0.0 14.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 3.7 21.0 8.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 9.8 47.8 0.3 1.1 0.0 33.9 0.2 0.1 0.1 0.0 0.0 4.3 0.4 1.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "Bloom syndrome RecQ like helicase" P54132 15 90717327-90816165 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 36.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 1.8 0.4 3.1 11.4 1.5 5.5 0.6 4.7 2.6 0.7 1.9 0.9 0.5 1.4 1.2 1.1 2.9 0.4 1.3 1.0 2.3 2.4 0.9 0.5 2.0 7.7 2.8 0.2 0.9 0.4 0.0 1.2 3.6 0.5 0.7 2.5 0.7 7.8 0.0 1.7 0.6 2.8 0.5 1.9 6.7 1.4 4.9 0.5 36.7 0.6 3.1 9.3 1.4 0.7 7.4 1.2 4.3 1.6 4.6 5.0 1.6 5.4 7.8 8.7 5.1 0.0 0.4 5.5 4.1 1.2 4.7 5.1 6.8 3.8 14.1 2.6 1.1 9.1 13.4 3.7 6.1 8.5 9.9 14.7 8.4 2.2 0.0 14.1 7.3 0.0 0.0 4.7 2.4 3.3 12.7 4.4 4.9 3.4 10.6 7.8 9.3 1.7 10.8 16.4 5.4 1.1 9.8 6.5 6.1 3.3 4.4 2.6 3.1 11.6 1.8 3.4 6.3 3.5 8.7 3.2 13.1 14.7 1.9 10.0 5.8 2.5 1.0 4.3 3.1 1.2 4.8 7.4 2.8 3.8 1.2 4.3 2.0 2.2 0.8 4.6 1.6 1.2 5.0 1.6 3.1 1.5 4.7 1.7 2.3 2.4 2.8 0.2 0.5 0.5 BLMH BH ENSG00000108578 "Bleomycin hydrolase" Q13867 17 30248195-30292056 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 67.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039548, HPA064307" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" 59000000 "Nucleoplasm, Nuclear bodies, Cytosol" "HPA039548: AB_10805479, HPA064307: AB_2685241" "unprognostic (6.85e-2)" "unprognostic (2.79e-1)" "unprognostic (1.48e-1)" "unprognostic (2.46e-1)" "unprognostic (1.76e-1)" "unprognostic (2.54e-2)" "unprognostic (3.91e-3)" "unprognostic (2.07e-1)" "unprognostic (2.05e-3)" "unprognostic (6.69e-3)" "unprognostic (1.95e-3)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.22e-3)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-1)" 11.2 8.3 9.0 17.1 10.2 8.5 14.2 12.1 14.5 10.5 9.8 8.5 9.6 6.7 13.1 12.2 15.7 8.4 10.1 9.7 7.5 7.2 13.6 7.5 13.6 20.3 9.5 8.5 8.8 15.3 15.0 8.3 14.6 9.2 8.4 8.5 7.3 12.8 9.5 15.0 67.5 10.0 15.7 11.1 13.2 9.2 12.4 8.6 24.7 9.3 15.5 13.6 10.8 11.7 4.6 6.6 0.9 5.7 9.8 17.3 6.3 10.1 16.1 15.6 10.8 10.7 11.5 7.5 9.5 5.9 15.0 13.0 23.6 3.0 30.3 17.0 7.6 7.1 33.7 13.0 12.7 8.0 26.5 18.6 14.5 20.0 15.6 33.8 11.5 13.5 0.9 11.7 6.8 22.0 39.6 12.4 6.2 7.7 41.8 24.7 14.9 7.5 36.3 40.5 20.0 12.0 9.1 36.0 12.9 8.4 16.4 10.3 11.2 17.5 14.0 9.3 18.7 4.1 16.8 15.0 30.8 40.9 7.1 0.0 12.4 0.0 5.7 0.9 10.5 3.9 17.3 4.6 12.6 13.7 6.5 4.2 11.6 12.3 0.7 9.8 1.9 6.6 12.4 6.3 9.0 10.2 12.1 14.5 7.5 7.2 9.5 8.5 9.2 8.6 BLVRA BLVR ENSG00000106605 "Biliverdin reductase A" P53004 7 43758680-43807342 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019709, HPA042865, HPA054322" Approved Supported Cytosol 1600000 Cytosol "HPA019709: , HPA042865: AB_10797024, HPA054322: " "unprognostic (2.47e-2)" "unprognostic (8.38e-3)" "unprognostic (1.79e-2)" "unprognostic (2.16e-3)" "unprognostic (6.45e-3)" "unprognostic (5.01e-2)" "unprognostic (1.63e-2)" "prognostic favourable (8.65e-4)" "unprognostic (1.42e-1)" "unprognostic (1.75e-2)" "unprognostic (2.93e-1)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (5.63e-3)" "unprognostic (3.18e-1)" "unprognostic (2.13e-3)" "unprognostic (4.56e-2)" 31.7 13.1 14.5 16.2 14.7 23.8 22.5 13.3 21.9 22.7 25.9 9.1 12.6 5.2 19.3 58.7 35.8 18.7 17.5 21.7 11.9 16.2 26.8 6.0 27.7 25.1 15.8 15.4 26.4 14.8 19.3 13.1 12.2 20.5 21.8 8.8 17.2 17.9 21.1 23.0 15.1 12.2 26.4 10.6 40.9 17.7 9.3 6.7 12.1 19.0 21.3 21.5 28.5 18.9 4.9 23.2 27.5 61.6 3.4 14.0 30.7 11.4 22.3 6.5 27.1 13.9 18.6 0.3 7.8 24.3 13.4 16.4 5.3 6.9 0.0 15.1 12.4 15.1 19.9 19.8 11.5 53.8 13.9 24.7 20.5 32.6 35.5 2.7 9.3 12.6 33.6 14.1 9.4 22.7 16.4 13.7 10.1 12.4 8.6 1.5 8.8 25.7 19.0 11.3 62.2 29.7 6.4 8.4 25.9 16.0 16.0 13.0 36.0 18.5 13.8 12.3 13.7 5.4 13.3 18.5 14.6 0.0 20.1 11.2 19.1 7.8 50.5 27.5 7.0 61.6 6.6 4.9 14.0 11.7 23.2 2.4 7.5 5.8 4.5 3.4 57.7 3.4 13.6 30.7 14.5 14.7 13.3 21.9 11.9 16.2 15.8 15.4 20.5 6.7 BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465840 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.6" "Cell line enhanced" "Detected in many" "A549: 82.6;K-562: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "classical monocyte: 73.4" "Group enriched" "Detected in all" 7 "dendritic cells: 54.8;monocytes: 73.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" 440000000 Cytosol "Nucleoplasm, Plasma membrane" "HPA041698: AB_10796781, HPA041937: AB_10794308" "unprognostic (1.86e-1)" "unprognostic (1.14e-2)" "unprognostic (4.23e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (1.20e-2)" "unprognostic (8.56e-2)" "unprognostic (1.35e-1)" "prognostic unfavourable (3.90e-4)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" 36.9 17.9 10.9 12.8 12.2 137.6 28.9 3.5 10.9 17.0 26.7 7.7 18.5 20.9 14.1 19.6 45.3 14.6 19.0 31.0 8.2 8.6 31.8 72.4 37.3 30.0 11.7 9.6 21.3 19.4 5.7 5.6 32.2 13.8 22.9 7.7 17.5 27.1 22.1 43.4 16.7 26.4 22.1 9.7 47.1 31.1 7.6 7.9 6.6 24.3 42.9 24.4 29.9 22.1 8.6 54.8 9.1 73.4 4.0 5.3 34.4 34.8 82.6 1.1 12.3 11.5 11.1 9.8 4.4 12.9 6.0 11.7 16.2 31.7 11.7 34.0 7.9 11.1 4.2 9.6 1.2 19.8 3.6 17.8 12.5 9.8 26.5 0.2 5.2 10.8 18.2 8.0 4.4 6.3 75.0 21.3 7.0 54.2 0.9 1.0 0.3 23.1 8.2 3.9 18.9 7.5 23.5 0.0 1.8 13.4 35.2 13.5 34.3 2.7 6.8 16.0 17.2 24.6 2.3 11.6 13.6 4.4 41.8 7.0 6.2 5.0 73.4 2.6 4.6 33.7 4.4 8.6 4.0 4.0 54.8 5.4 4.2 3.3 9.1 4.0 16.9 11.5 5.3 34.4 10.9 12.2 3.5 10.9 8.2 8.6 11.7 9.6 13.8 7.9 BMP1 PCOLC ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22164736-22212326 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "lung: 72.2;placenta: 106.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" 2100000 "HPA014572: AB_1845390" "unprognostic (1.24e-1)" "unprognostic (8.01e-2)" "unprognostic (3.75e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-2)" "unprognostic (6.76e-2)" "unprognostic (9.53e-2)" "unprognostic (2.64e-3)" "unprognostic (1.66e-1)" "unprognostic (9.75e-3)" "unprognostic (7.05e-3)" "unprognostic (3.14e-2)" "prognostic unfavourable (3.37e-9)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-3)" "unprognostic (3.34e-2)" 6.9 11.7 2.7 3.6 4.6 1.1 5.9 7.8 4.2 8.1 5.8 3.1 3.7 4.4 9.4 5.2 4.8 7.7 5.4 3.4 2.6 1.3 4.9 9.2 72.2 3.2 3.4 1.5 5.2 3.7 2.8 2.2 106.2 3.5 6.5 4.7 4.6 2.4 4.6 2.4 6.8 5.7 11.0 3.6 3.2 2.9 2.2 3.6 1.0 7.1 2.4 2.9 9.9 9.5 0.0 0.9 0.1 1.4 0.8 2.2 0.4 4.6 4.8 1.3 6.2 15.3 11.3 6.8 20.3 16.9 10.4 9.6 2.5 3.0 1.1 12.7 18.6 10.2 1.6 5.4 2.0 1.0 2.1 1.7 7.3 2.9 12.5 0.7 3.5 12.9 8.5 8.1 2.6 10.0 2.2 2.1 5.6 1.7 0.5 1.0 0.8 2.6 1.1 3.3 4.9 9.0 0.7 0.8 3.3 14.6 0.8 3.3 0.9 2.0 12.7 2.7 6.0 6.5 6.0 1.0 0.6 0.2 5.3 2.7 7.5 0.0 1.4 0.0 2.2 0.7 1.4 0.0 0.4 1.0 0.0 0.0 0.3 1.7 0.1 0.8 0.5 0.9 0.0 0.4 2.7 4.6 7.8 4.2 2.6 1.3 3.4 1.5 3.5 3.6 BMP2K "BIKe, DKFZp434K0614" ENSG00000138756 "BMP2 inducible kinase" Q9NSY1 4 78776342-78916372 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 37.9;HMC-1: 41.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026436, HPA026451, HPA026501" Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA026436: AB_10600102, HPA026451: AB_10600228, HPA026501: AB_10601341" "unprognostic (7.96e-2)" "unprognostic (3.68e-1)" "prognostic favourable (1.74e-4)" "unprognostic (9.08e-2)" "unprognostic (1.97e-1)" "unprognostic (9.73e-3)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.39e-1)" "unprognostic (9.60e-2)" "unprognostic (9.90e-2)" "unprognostic (9.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.18e-2)" 11.4 11.1 15.6 18.6 15.0 15.3 12.0 8.2 12.7 11.1 13.9 20.3 2.1 8.0 11.3 9.6 15.7 10.0 12.3 17.0 18.0 9.5 8.3 10.2 14.1 22.9 20.9 12.0 6.5 6.4 7.7 7.8 14.4 14.5 8.4 18.9 11.4 10.2 6.0 7.5 14.5 15.9 10.4 28.3 19.2 7.4 19.6 16.5 19.9 12.5 5.9 24.4 9.7 12.8 2.7 1.7 3.8 2.6 0.4 0.4 0.5 5.4 2.0 3.0 3.9 5.9 5.6 2.3 5.2 8.1 5.9 7.7 3.7 2.9 6.6 2.7 25.2 1.3 3.5 4.2 10.8 1.8 1.2 37.9 2.4 1.7 6.5 7.9 41.1 8.2 5.5 9.2 8.5 7.9 10.2 19.0 6.9 1.1 4.7 3.3 1.4 1.3 6.8 5.4 1.6 7.2 2.9 4.7 2.5 7.6 3.9 4.6 1.4 4.1 7.7 5.8 2.3 9.6 5.6 3.5 1.4 2.5 5.1 9.9 4.0 0.4 2.2 1.2 0.1 0.9 0.1 2.7 0.1 0.0 1.7 2.7 0.4 0.2 3.8 0.4 2.6 1.3 0.0 0.5 15.6 15.0 8.2 12.7 18.0 9.5 20.9 12.0 14.5 16.5 BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932838 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol Cytosol "CAB019398: " "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (3.34e-1)" "unprognostic (9.61e-2)" "unprognostic (1.05e-3)" "unprognostic (9.34e-2)" "prognostic unfavourable (8.93e-4)" "unprognostic (3.64e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (9.24e-2)" "unprognostic (9.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (1.07e-1)" 8.9 7.0 9.4 7.9 12.4 0.9 10.7 14.1 9.2 19.4 20.6 10.9 7.7 6.2 16.3 12.3 8.4 10.9 10.8 11.0 7.7 6.1 8.2 4.6 7.4 2.9 7.3 7.6 16.1 10.6 10.0 14.0 7.4 8.5 12.8 9.3 10.9 12.6 14.2 8.4 11.3 9.8 16.5 12.2 3.4 12.1 7.8 9.2 0.3 19.4 7.8 5.7 16.0 11.4 1.8 1.1 3.6 0.8 0.9 1.4 0.3 7.5 3.8 14.7 12.5 7.7 5.0 2.6 7.6 8.0 4.5 5.2 6.5 6.7 2.3 3.5 9.7 8.1 6.5 8.3 6.6 2.5 3.7 2.9 3.6 10.7 4.1 4.0 20.4 4.4 3.5 6.0 4.4 0.0 4.5 1.6 5.2 3.2 2.6 3.2 8.0 1.8 0.0 5.8 0.0 9.2 7.2 1.5 4.8 8.5 4.3 5.1 7.3 2.0 3.8 3.2 5.2 6.6 7.0 0.4 7.0 2.9 2.8 2.7 2.6 2.0 0.8 0.6 1.4 0.5 0.9 1.8 1.4 1.2 0.3 1.5 1.0 1.1 3.6 0.9 0.6 1.1 0.7 0.3 9.4 12.4 14.1 9.2 7.7 6.1 7.3 7.6 8.5 9.2 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376936-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA017385: AB_1845397, HPA049014: " "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.1 15.0 12.1 9.8 14.2 1.1 10.2 9.5 17.1 15.7 11.7 8.2 6.5 5.5 12.9 10.2 10.6 10.3 13.2 14.6 10.8 13.5 10.7 11.5 24.9 4.4 10.4 14.5 12.0 7.0 15.5 6.1 21.7 10.8 11.0 7.7 11.4 7.1 9.1 10.6 7.2 8.1 15.3 7.5 8.9 7.2 12.9 3.8 3.9 11.6 5.2 5.4 11.1 8.9 1.6 2.6 0.9 2.7 1.1 3.6 0.9 5.7 5.4 5.5 8.7 13.9 13.4 10.7 11.9 12.0 10.4 10.4 4.7 8.7 2.0 13.9 24.0 10.8 7.2 9.2 16.3 5.9 4.9 6.0 5.7 7.3 9.6 1.7 4.7 9.8 8.7 7.6 10.2 30.0 3.9 9.9 12.8 10.7 1.4 1.5 3.0 4.9 3.9 10.9 3.0 8.9 12.2 5.6 5.6 12.6 7.6 14.0 5.8 4.0 33.0 21.2 11.3 7.2 7.2 1.4 1.7 0.6 5.1 3.8 6.1 0.5 2.0 0.9 3.4 1.8 2.5 1.5 1.3 2.2 2.3 1.6 2.7 1.4 0.6 1.1 2.7 2.6 3.6 0.9 12.1 14.2 9.5 17.1 10.8 13.5 10.4 14.5 10.8 3.8 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 57.1" "Cell line enriched" "Detected in single" 121 "HUVEC TERT2: 88.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 17 "neutrophil: 10.5" "Lineage enriched" "Detected in single" 105 "granulocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 8.2 0.3 0.1 1.0 0.7 3.6 5.4 0.1 0.3 2.2 5.5 0.1 4.6 2.4 2.6 57.1 1.5 2.5 2.6 10.5 0.5 0.0 0.2 0.9 3.7 6.5 0.4 0.0 1.4 0.9 0.2 0.6 2.6 0.7 2.2 1.4 0.5 1.5 0.6 4.2 1.6 5.5 2.2 0.4 2.4 1.5 1.9 0.1 0.2 2.2 1.1 0.8 2.8 2.4 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.3 0.5 0.0 0.4 0.0 0.7 0.1 BPGM ENSG00000172331 "Bisphosphoglycerate mutase" P07738 7 134646808-134679813 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Congenital erythrocytosis, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "placenta: 184.7" "Cell line enhanced" "Detected in all" "HDLM-2: 37.1;RT4: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016493, HPA028735" Enhanced Approved Nucleoplasm,Nucleoli 69000000 Nucleoli Nucleoplasm "HPA016493: AB_1845414, HPA028735: AB_10600791" "unprognostic (2.56e-1)" "prognostic favourable (7.95e-4)" "unprognostic (3.19e-1)" "unprognostic (3.94e-1)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (3.81e-3)" "unprognostic (1.96e-1)" "unprognostic (7.74e-2)" "unprognostic (4.67e-3)" "unprognostic (7.42e-2)" "unprognostic (5.69e-2)" "prognostic favourable (1.54e-8)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (3.78e-2)" 6.1 7.3 13.6 4.5 11.1 37.7 6.9 11.7 11.6 7.1 6.9 9.1 6.1 4.3 5.4 10.2 14.6 4.7 6.9 7.3 12.5 14.2 19.1 8.1 8.0 5.2 13.9 7.8 5.7 5.4 16.5 14.4 184.7 12.4 7.5 5.4 6.7 10.6 10.3 17.7 5.5 6.0 6.6 15.9 8.6 6.8 7.4 8.8 8.5 7.5 22.2 13.3 24.9 9.5 11.6 10.2 28.2 12.8 9.8 14.5 12.8 4.4 5.4 7.2 9.7 8.3 4.9 7.2 13.4 16.2 5.2 7.8 2.1 6.0 5.4 4.0 7.5 3.6 7.6 7.4 9.2 37.1 6.7 3.1 5.0 2.5 5.7 5.9 4.1 4.8 6.7 9.8 5.3 18.9 9.0 6.8 12.3 2.1 9.6 8.2 7.4 5.2 7.3 5.1 3.9 11.8 59.6 6.2 10.4 6.2 7.5 6.7 4.9 3.8 14.3 8.3 2.0 11.1 10.8 11.3 12.9 6.8 14.4 5.7 14.2 28.2 9.8 27.6 14.5 12.8 10.4 11.6 9.5 12.7 10.2 10.5 13.2 13.4 18.0 9.8 12.5 6.7 12.0 12.8 13.6 11.1 11.7 11.6 12.5 14.2 13.9 7.8 12.4 8.8 BPNT1 ENSG00000162813 "3'(2'), 5'-bisphosphate nucleotidase 1" O95861 1 220057482-220090462 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048461 Approved Approved "Nuclear speckles" 170000 "Nuclear speckles" "HPA048461: " "unprognostic (6.42e-2)" "unprognostic (4.69e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (5.19e-3)" "unprognostic (7.65e-2)" "unprognostic (2.07e-2)" "unprognostic (3.00e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (6.69e-2)" "unprognostic (2.87e-1)" "prognostic favourable (6.38e-4)" "unprognostic (1.82e-2)" "unprognostic (6.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" 11.1 24.1 12.7 22.2 17.2 2.9 13.4 13.7 16.5 12.9 27.9 15.9 14.4 30.5 10.6 8.0 14.9 11.5 16.1 11.6 11.3 10.8 31.0 17.0 11.5 21.5 14.0 10.6 13.5 8.6 14.1 20.2 12.7 11.9 9.6 22.5 11.8 22.2 12.2 7.6 10.6 49.0 12.3 17.6 12.0 12.9 10.4 13.3 15.6 13.8 12.6 28.8 13.5 10.4 18.9 10.9 11.6 8.5 12.1 13.8 7.6 11.7 9.7 7.3 5.8 13.0 10.4 10.9 15.8 7.7 13.6 12.6 12.7 23.8 59.4 20.8 10.2 8.5 14.7 13.2 11.0 21.3 17.1 10.7 12.5 15.6 7.6 28.4 10.1 9.8 6.3 20.1 7.5 10.6 18.5 5.9 13.0 6.6 16.3 7.8 6.2 11.9 11.7 21.0 16.8 16.9 16.1 13.5 11.1 19.9 24.0 13.0 18.8 9.8 17.7 8.5 6.6 11.8 19.5 10.4 25.2 28.1 7.6 10.6 19.2 11.6 7.8 5.0 11.0 8.5 8.7 18.9 11.3 11.0 9.0 14.1 13.8 10.2 1.1 12.1 7.8 10.9 11.5 7.6 12.7 17.2 13.7 16.5 11.3 10.8 14.0 10.6 11.9 13.3 BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924928 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Approved Approved Vesicles,Cytosol Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: " "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" 13.1 12.1 20.1 16.5 20.4 27.8 14.2 29.9 21.5 12.4 12.3 9.5 12.5 9.3 15.3 17.0 11.8 11.5 12.0 13.6 13.2 12.2 13.7 12.8 15.9 13.3 9.9 17.8 16.8 13.2 28.9 24.8 13.7 15.3 14.5 11.0 10.7 11.6 16.6 12.9 15.6 10.5 13.0 10.9 12.3 12.0 24.9 12.2 13.5 16.6 7.5 12.1 18.6 18.1 2.6 1.9 7.5 2.4 7.0 5.6 1.1 5.4 4.6 6.8 8.1 8.3 10.7 10.9 6.1 6.5 4.9 7.1 5.0 5.9 9.3 4.7 6.2 3.0 6.0 4.8 9.0 8.6 4.9 6.0 4.5 4.6 7.0 9.8 6.1 7.1 5.4 5.2 10.8 5.7 9.5 16.7 8.7 2.9 13.0 10.3 6.3 2.9 8.5 5.8 7.6 4.8 10.4 7.9 6.6 7.0 4.3 6.3 4.0 6.7 8.4 5.3 4.1 11.5 4.9 19.4 11.0 14.8 8.7 9.9 5.7 3.3 2.0 7.5 3.1 1.7 2.1 2.6 3.0 2.4 1.6 2.6 5.6 2.8 4.1 7.0 2.4 1.9 2.7 1.1 20.1 20.4 29.9 21.5 13.2 12.2 9.9 17.8 15.3 12.2 BRAP "BRAP2, IMP, RNF52" ENSG00000089234 "BRCA1 associated protein" Q7Z569 12 111642146-111685986 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040357, HPA058820" Approved Supported "Nuclear membrane,Cytosol" Cytosol "Nuclear membrane" "HPA040357: AB_10967924, HPA058820: " "unprognostic (7.02e-2)" "unprognostic (2.37e-3)" "unprognostic (5.33e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-1)" "unprognostic (1.69e-1)" "prognostic unfavourable (7.65e-6)" "unprognostic (2.14e-1)" "unprognostic (9.24e-3)" "unprognostic (2.80e-1)" "unprognostic (1.81e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (3.66e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-2)" "unprognostic (8.08e-2)" 9.8 9.9 9.8 7.2 11.6 26.5 9.6 10.0 12.8 8.3 9.3 10.0 8.0 8.6 10.1 7.0 9.4 8.4 7.3 8.8 8.6 8.7 8.4 9.3 7.9 9.7 9.2 8.5 9.7 7.8 9.4 10.4 9.8 12.0 8.3 9.0 6.7 8.9 9.7 19.1 12.7 9.3 9.1 11.1 9.6 7.9 55.9 10.1 12.4 9.5 5.6 10.4 10.2 11.8 12.7 11.7 25.7 13.5 16.6 18.5 11.6 9.7 14.4 11.8 13.5 12.6 10.7 19.7 13.7 11.6 16.0 12.3 19.3 6.8 18.8 8.2 13.0 12.0 16.4 11.2 17.1 12.0 10.6 23.3 9.0 13.0 15.9 20.4 15.8 12.0 16.0 13.8 22.4 13.8 24.1 6.2 13.1 12.3 16.9 19.7 15.9 15.2 15.8 12.9 16.8 10.5 20.6 14.7 10.9 16.1 13.7 13.4 15.0 13.0 12.7 10.3 9.6 9.2 9.7 15.9 20.0 20.8 9.7 11.3 11.2 16.1 13.0 24.0 14.7 13.5 14.3 12.7 15.4 14.7 11.7 12.5 14.6 14.8 25.7 16.6 10.6 8.4 18.5 11.6 9.8 11.6 10.0 12.8 8.6 8.7 9.2 8.5 12.0 10.1 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1, DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 9.1;granulocytes: 9.7;monocytes: 12.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: " "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 4.8 4.3 6.0 9.6 11.3 15.3 5.1 12.9 10.6 5.4 9.2 3.4 6.8 4.3 5.4 5.5 9.1 5.5 3.3 6.5 6.6 5.3 4.2 7.7 4.9 13.0 7.5 5.9 5.1 4.7 4.2 11.0 5.3 10.5 4.1 10.4 3.7 5.4 7.4 7.3 8.3 6.7 5.5 9.2 5.9 5.1 17.6 7.0 10.9 15.6 7.3 14.6 5.5 5.6 2.0 9.1 9.7 12.7 1.4 1.3 10.7 15.5 25.2 13.9 11.1 2.3 5.2 13.6 18.3 7.9 15.4 14.7 15.3 12.1 35.9 3.4 7.0 18.0 18.9 10.2 25.9 16.4 13.8 16.9 19.8 13.2 0.5 30.1 14.7 1.4 1.7 23.2 7.4 7.9 25.4 15.4 14.5 10.3 25.2 9.9 7.6 6.7 17.4 29.3 14.7 5.7 15.1 9.6 10.3 14.1 4.7 6.9 12.4 13.9 5.2 13.8 11.2 17.8 19.1 7.2 17.6 27.6 11.1 17.9 14.4 4.6 12.7 1.8 1.3 4.0 1.3 1.1 1.3 1.0 9.1 2.0 1.2 1.3 9.7 1.4 1.5 1.4 0.4 10.7 6.0 11.3 12.9 10.6 6.6 5.3 7.5 5.9 10.5 7.0 BRCC3 "BRCC36, C6.1A, CXorf53" ENSG00000185515 "BRCA1/BRCA2-containing complex subunit 3" P46736 X 155071420-155123074 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Metalloprotease, Protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048737 Supported Nucleoplasm Nucleoplasm "HPA048737: " "unprognostic (1.16e-2)" "unprognostic (2.40e-2)" "unprognostic (5.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (2.88e-2)" "unprognostic (4.48e-2)" "unprognostic (6.47e-3)" "unprognostic (1.33e-1)" "unprognostic (9.68e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (3.71e-3)" "unprognostic (7.14e-3)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "unprognostic (1.90e-1)" 12.9 14.8 11.3 11.2 16.5 14.0 12.9 20.0 18.6 11.8 19.5 9.1 15.2 16.7 9.4 11.8 20.4 12.1 8.3 10.3 10.3 12.1 18.3 12.3 9.4 12.5 10.4 10.5 10.7 12.2 14.3 11.8 14.2 15.3 12.2 19.5 8.7 15.5 12.6 21.3 10.0 19.2 13.1 8.9 11.1 13.7 3.9 12.9 10.2 13.9 13.7 12.7 11.4 11.6 13.4 16.2 25.0 17.8 21.0 19.0 12.3 31.4 19.5 8.2 6.4 6.2 5.1 13.6 12.9 8.2 7.9 17.5 17.6 13.8 30.3 23.6 8.2 12.2 21.1 11.5 11.5 17.6 16.9 6.1 30.7 14.6 5.5 21.4 9.5 6.3 5.2 12.9 11.0 10.8 9.9 9.0 6.4 13.3 8.2 7.6 7.3 13.9 12.9 14.1 12.6 9.5 14.9 13.5 5.8 8.5 13.6 7.7 9.4 7.3 12.1 7.1 10.9 10.4 19.4 11.5 18.7 39.4 10.3 20.1 8.2 22.6 14.7 25.0 16.2 17.8 19.0 13.4 16.0 14.8 16.2 11.8 12.5 14.0 8.0 21.0 16.9 10.4 18.6 12.3 11.3 16.5 20.0 18.6 10.3 12.1 10.4 10.5 15.3 12.9 BRIP1 "BACH1, FANCJ, OF" ENSG00000136492 "BRCA1 interacting protein C-terminal helicase 1" Q9BX63 17 61681266-61863521 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Cell line enhanced" "Detected in many" "MCF7: 41.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 2.2;granulocytes: 2.1;T-cells: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005474 Approved Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA005474: AB_2667333" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "prognostic favourable (3.45e-5)" "unprognostic (6.85e-4)" "unprognostic (3.09e-1)" "prognostic favourable (3.62e-4)" "unprognostic (2.60e-3)" "unprognostic (5.60e-2)" "unprognostic (5.66e-3)" "unprognostic (6.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.75e-2)" "unprognostic (3.41e-12)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (3.96e-2)" "unprognostic (3.62e-3)" 1.0 0.9 0.7 6.3 3.5 9.1 1.1 0.6 1.4 1.4 2.6 0.2 0.6 2.8 1.5 1.2 3.7 0.8 1.8 0.4 0.5 0.5 0.6 2.3 1.3 4.0 0.5 0.9 2.1 1.3 0.1 0.4 1.7 0.7 1.0 2.8 0.4 1.4 0.0 0.4 2.7 5.5 1.0 0.5 2.3 1.3 10.8 0.4 30.1 0.4 2.0 6.6 1.3 1.7 2.2 0.5 2.1 0.3 0.6 3.7 0.5 12.3 4.2 12.2 6.9 0.4 1.1 2.7 11.4 6.7 12.2 15.8 4.3 3.9 7.3 2.6 2.4 4.5 6.3 2.3 16.4 1.8 7.7 7.5 6.7 5.3 0.1 9.6 4.4 0.2 0.1 9.7 2.6 2.6 5.2 5.0 7.6 41.4 15.2 3.3 2.6 3.6 9.5 23.4 3.5 1.6 5.6 4.9 12.7 4.4 1.5 1.8 4.1 3.7 2.2 18.0 13.1 6.6 13.1 3.1 6.0 7.9 3.7 4.6 4.5 2.1 0.3 1.5 0.5 0.2 0.6 2.2 1.2 0.6 0.4 1.8 1.8 0.9 1.0 0.6 0.2 0.5 3.7 0.5 0.7 3.5 0.6 1.4 0.5 0.5 0.5 0.9 0.7 0.4 BRSK1 KIAA1811 ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312533 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.0" "Cell line enhanced" "Detected in many" "SCLC-21H: 25.9;SH-SY5Y: 23.2;WM-115: 21.1" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported Nucleoplasm Nucleoplasm "HPA021212: AB_1845455, HPA061719: " "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favourable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavourable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" 1.4 9.8 28.6 3.2 23.6 1.0 1.6 26.7 65.0 1.8 2.2 7.9 0.1 3.3 5.4 3.7 3.0 2.3 3.9 6.5 33.4 20.0 1.4 0.8 1.7 2.4 20.4 14.8 2.4 2.6 12.4 11.0 1.5 13.3 3.8 1.9 2.8 2.5 4.6 1.0 1.1 2.6 4.9 9.2 1.5 1.9 4.4 7.2 0.0 3.0 0.0 1.6 3.2 0.7 0.0 0.3 0.0 0.9 0.1 0.8 0.2 0.3 1.2 15.3 8.0 0.0 0.6 0.1 2.4 3.4 3.3 4.8 5.9 2.7 3.1 1.7 2.7 0.1 3.2 0.1 3.1 14.4 12.6 2.0 1.6 0.6 3.3 0.6 5.9 2.1 0.3 3.3 0.0 0.1 2.8 18.8 2.9 0.8 3.6 0.7 11.1 1.0 8.3 3.8 0.5 0.2 0.0 25.9 23.2 0.0 0.4 5.6 1.3 1.7 0.0 6.3 6.7 3.5 4.6 15.6 11.4 7.0 6.5 1.4 21.1 0.0 0.9 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.2 28.6 23.6 26.7 40.2 33.4 20.0 20.4 14.8 13.3 7.2 BRSK2 "C11orf7, PEN11B, STK29" ENSG00000174672 "BR serine/threonine kinase 2" Q8IWQ3 11 1389899-1462689 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Exocytosis, Mitosis, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 34.9;pancreas: 78.8" "Cell line enhanced" "Detected in some" "AF22: 8.9;AN3-CA: 9.7;CACO-2: 7.7;HAP1: 7.2;NTERA-2: 15.0;SCLC-21H: 35.0" "Cancer enhanced" "Detected in many" "glioma: 3.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 13 "NK-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073690 Approved "Golgi apparatus" "Golgi apparatus" "HPA073690: " "unprognostic (5.47e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.05e-2)" "unprognostic (3.63e-1)" "unprognostic (6.42e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-2)" "unprognostic (2.31e-1)" "unprognostic (3.17e-7)" "unprognostic (3.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "unprognostic (1.86e-1)" 1.5 3.5 13.6 1.5 12.8 1.3 1.3 30.8 34.9 1.3 1.5 10.0 0.0 1.7 1.4 1.3 1.3 1.4 1.9 1.5 15.6 10.6 1.4 1.3 1.4 1.3 8.3 17.2 1.4 78.8 1.6 4.6 1.8 9.5 1.6 1.4 2.2 1.6 1.4 1.5 1.5 1.9 1.4 6.5 1.3 1.9 5.5 9.2 0.0 1.9 0.0 1.3 1.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 3.9 8.9 9.7 0.1 0.3 0.0 0.1 0.1 0.7 0.3 7.7 0.5 0.0 1.3 0.1 0.0 7.2 0.0 0.6 0.9 3.8 0.0 0.0 0.1 0.4 0.0 0.3 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.9 0.0 0.0 15.0 1.2 0.0 0.0 0.0 0.1 0.1 35.0 5.2 1.7 0.1 2.4 0.2 0.4 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 13.6 12.8 30.8 23.3 15.6 10.6 8.3 17.2 9.5 9.2 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15702950-15738313 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 59.5;bone marrow: 54.9;intestine: 61.3" "Cell line enhanced" "Detected in many" "THP-1: 36.3;TIME: 20.0;U-937: 23.7;WM-115: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 52.7;neutrophil: 59.5" "Group enriched" "Detected in many" 105 "dendritic cells: 16.6;granulocytes: 59.5;monocytes: 52.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" 170000000 "HPA050121: " "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 14.3 2.0 1.1 5.6 2.0 54.9 6.6 0.8 1.5 7.2 33.8 1.5 2.1 20.4 6.4 7.0 4.6 5.6 10.3 14.5 1.8 0.8 6.6 3.7 9.4 9.6 1.3 1.9 5.5 1.0 0.4 1.3 8.0 1.3 7.5 4.0 5.4 2.8 2.2 3.4 3.5 61.3 7.9 1.5 13.6 2.4 2.4 1.2 2.8 3.5 2.9 1.8 7.5 16.1 0.4 16.6 59.5 52.7 0.1 0.3 19.6 0.2 5.4 0.5 0.4 13.2 3.1 0.7 10.3 0.9 9.4 10.6 0.1 5.6 0.3 0.9 5.2 0.1 1.5 0.2 8.0 0.3 0.2 2.4 0.3 0.2 3.4 3.2 7.1 2.7 0.7 6.0 0.5 1.4 0.3 0.2 5.5 0.1 1.0 1.9 1.2 1.1 0.3 0.7 0.2 0.3 0.3 0.7 2.0 0.2 0.3 6.8 0.2 36.3 20.0 0.3 0.4 3.7 0.4 0.2 0.0 0.2 1.3 23.7 21.6 7.6 52.7 3.9 0.2 19.8 0.3 0.4 0.1 0.1 16.6 0.2 0.2 0.1 59.5 0.1 13.6 5.5 0.2 19.6 1.1 2.0 0.8 1.5 1.8 0.8 1.3 1.9 1.3 1.2 BTD ENSG00000169814 Biotinidase P43251 3 15601341-15647640 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052275 Uncertain "Secreted to blood" 2900000000 "HPA052275: " "unprognostic (6.04e-2)" "unprognostic (2.42e-1)" "unprognostic (9.37e-3)" "unprognostic (5.84e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-2)" "unprognostic (6.37e-3)" "unprognostic (4.26e-2)" "unprognostic (3.29e-2)" "unprognostic (1.23e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "prognostic favourable (2.60e-9)" "unprognostic (2.44e-2)" "unprognostic (4.90e-2)" "unprognostic (1.67e-3)" "unprognostic (3.73e-2)" 18.5 17.9 7.5 3.9 10.2 4.4 13.5 17.0 11.8 11.2 28.1 19.6 12.2 25.3 12.3 34.1 7.1 10.3 10.4 6.9 8.0 6.8 20.0 50.7 8.2 5.2 12.3 9.5 17.2 26.6 19.6 11.1 10.7 9.3 10.7 9.4 20.0 11.6 12.1 6.9 6.5 40.5 7.9 8.8 7.6 12.9 15.0 12.6 5.9 14.8 3.8 6.2 11.7 9.1 8.4 13.7 31.0 11.9 7.5 15.6 8.7 3.8 10.8 3.3 3.2 28.2 7.8 19.6 7.0 9.4 8.3 15.0 3.8 10.3 1.0 8.4 16.1 4.3 2.6 8.3 9.7 3.3 5.5 5.9 14.5 11.6 6.8 2.9 6.9 9.5 8.6 21.8 2.2 15.9 3.8 13.7 23.3 4.6 1.6 3.4 3.6 6.0 2.1 8.2 13.0 8.0 7.8 2.3 5.7 8.3 2.0 11.0 10.2 5.6 10.8 9.0 6.9 8.3 4.4 3.2 4.8 1.2 10.5 3.5 6.5 31.0 11.9 25.2 13.2 11.1 12.3 8.4 14.1 11.3 12.1 7.8 12.2 9.2 10.8 7.5 8.4 13.7 15.6 8.7 7.5 10.2 17.0 11.8 8.0 6.8 12.3 9.5 9.3 12.6 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 77.5;lymphoid tissue: 37.0" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HEL: 40.0;HMC-1: 144.1;U-937: 20.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 77.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" 610000 "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 7.3 2.4 3.3 23.5 5.6 14.0 2.6 0.8 3.6 2.3 3.0 4.7 0.3 2.2 1.9 2.6 2.4 2.0 3.7 3.3 3.3 2.5 2.2 2.5 10.7 25.1 5.4 1.2 1.2 1.5 0.2 1.4 3.2 4.1 2.5 4.5 1.5 3.2 1.0 1.0 2.5 12.9 3.3 10.8 37.0 3.1 1.3 6.3 4.0 1.7 1.8 36.7 5.8 2.0 13.7 13.2 77.5 20.7 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.0 0.0 16.0 144.1 0.0 0.0 0.0 0.0 0.0 8.4 0.3 0.0 0.0 0.0 11.2 0.2 0.0 12.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 13.7 0.0 20.9 0.0 77.5 11.3 19.3 0.0 18.1 0.0 13.7 0.0 0.0 13.2 13.7 0.0 0.0 4.5 0.0 20.7 6.0 0.0 6.1 3.3 5.6 0.8 3.6 3.3 2.5 5.4 1.2 4.1 6.3 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637698-110678114 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 56.5;testis: 30.9" "Cell line enhanced" "Detected in many" "HEL: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "T-reg: 6.1" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavourable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavourable (1.03e-5)" "prognostic unfavourable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavourable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 1.1 0.9 0.5 15.8 1.0 8.9 0.6 0.3 1.0 1.2 2.8 0.4 0.0 2.4 0.7 2.3 5.8 0.5 1.0 1.1 0.5 0.5 0.9 0.8 2.1 11.6 0.6 0.2 1.0 0.7 0.0 0.4 2.4 0.5 0.7 4.3 0.4 1.4 0.0 0.5 1.8 3.1 1.4 1.3 7.9 1.8 30.9 0.1 56.5 0.6 5.7 12.1 2.5 2.0 1.8 2.4 3.0 0.2 1.4 6.1 1.1 29.9 8.8 23.1 14.5 1.0 1.7 12.3 15.6 10.3 27.2 20.5 18.4 17.2 20.3 9.7 9.0 13.1 29.5 11.3 33.8 16.1 14.4 67.2 9.4 14.7 0.2 19.3 19.0 0.4 0.7 20.9 10.4 15.8 29.4 42.4 22.2 9.8 32.3 16.2 22.3 16.6 21.5 19.8 31.0 5.5 9.5 15.5 6.7 11.1 9.4 8.4 7.4 16.4 6.5 12.4 20.2 9.3 21.6 22.2 20.8 25.0 8.3 15.0 21.7 3.0 0.0 0.7 0.6 0.2 0.9 1.8 2.5 1.0 0.8 1.4 1.6 1.5 0.0 1.4 0.1 2.4 6.1 1.1 0.5 1.0 0.3 1.0 0.5 0.5 0.6 0.2 0.5 0.1 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221136 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.5;testis: 25.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.8;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA008419 Supported Cytosol Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavourable (7.43e-6)" "prognostic unfavourable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavourable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 1.0 0.9 0.3 18.4 0.6 11.4 1.5 0.4 0.5 1.3 4.0 0.4 0.1 3.3 1.1 0.8 6.5 0.5 1.1 0.6 0.4 0.4 0.8 0.7 1.8 8.7 0.4 0.3 0.6 0.5 0.0 0.4 3.4 0.5 0.6 4.4 0.3 1.6 0.1 0.7 2.3 2.9 1.2 0.6 5.4 1.7 25.6 0.1 49.5 0.5 3.1 10.6 1.1 2.0 2.8 2.8 0.0 0.2 0.7 0.7 0.5 21.6 11.0 35.1 13.9 0.8 2.5 11.3 20.5 11.5 22.0 19.1 16.0 8.3 19.6 11.5 7.4 24.4 33.1 11.1 24.0 16.8 17.8 28.6 28.4 14.9 0.0 25.7 15.7 0.5 0.6 13.4 12.7 15.9 24.6 20.9 21.9 7.3 20.2 15.7 23.7 12.5 21.7 28.8 14.8 6.7 11.0 22.9 14.1 12.7 12.1 4.5 14.1 13.4 9.2 16.9 17.9 16.8 18.2 10.9 18.5 32.0 9.0 29.0 21.9 0.0 0.0 0.0 0.2 0.2 0.3 2.4 0.7 0.6 0.7 2.8 0.1 0.4 0.0 0.7 0.1 2.8 0.0 0.5 0.3 0.6 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.1 C1GALT1 "C1GALT, T-synthase" ENSG00000106392 "Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1" Q9NS00 7 7156934-7248651 "Enzymes, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "LHCN-M2: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011294, HPA012819" Enhanced Approved "Nuclear bodies,Cytosol" 10000 "Nuclear bodies, Cytosol" "HPA011294: AB_1845623, HPA012819: AB_1845624" "unprognostic (1.52e-1)" "prognostic unfavourable (1.04e-4)" "unprognostic (7.38e-2)" "unprognostic (8.78e-2)" "unprognostic (2.97e-2)" "unprognostic (1.04e-2)" "prognostic unfavourable (1.42e-5)" "unprognostic (2.03e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.40e-1)" "unprognostic (2.83e-1)" "unprognostic (3.28e-1)" "unprognostic (8.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.33e-1)" 11.4 7.7 10.1 12.4 14.1 23.1 11.0 10.6 14.9 13.9 10.7 21.5 4.0 19.3 5.4 7.1 24.7 12.7 16.1 11.6 12.8 10.8 21.5 14.7 10.9 11.7 23.7 8.9 6.2 6.2 42.3 11.0 30.2 19.2 5.7 12.2 8.1 17.6 5.7 8.1 8.6 15.8 5.3 31.0 13.8 15.3 5.4 21.4 12.9 10.6 6.2 11.6 10.3 8.4 15.9 13.5 33.2 26.0 16.6 17.4 12.2 18.7 8.1 2.5 4.3 7.4 15.5 8.7 21.5 16.1 10.0 14.9 5.5 19.4 8.7 5.5 8.5 6.0 3.6 8.0 15.8 5.2 3.0 8.2 4.8 15.3 8.1 8.6 3.6 12.7 5.7 24.6 19.0 8.1 17.7 5.5 80.7 3.2 2.3 4.2 15.6 8.7 7.9 14.7 5.3 11.4 8.3 3.0 8.1 13.6 15.3 14.6 4.8 4.5 8.6 16.1 24.9 22.9 8.7 10.5 8.9 9.9 10.6 11.7 17.8 33.2 11.1 31.2 16.1 16.5 16.9 15.9 15.0 17.4 12.2 13.7 15.7 17.0 24.3 16.6 26.0 13.5 13.0 12.2 10.1 14.1 10.6 14.9 12.8 10.8 23.7 8.9 19.2 21.4 C1R ENSG00000159403 "Complement C1r" P00736 12 7080209-7092607 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 370.2" "Cell line enhanced" "Detected in many" "ASC diff: 177.7;ASC TERT1: 90.7;BJ hTERT+: 78.2;BJ hTERT+ SV40 Large T+ RasG12V: 48.2;HSkMC: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 2.0;gdT-cell: 1.6;MAIT T-cell: 2.0;memory CD4 T-cell: 1.4;memory CD8 T-cell: 3.4;naive CD4 T-cell: 2.8;naive CD8 T-cell: 2.9;neutrophil: 2.5;NK-cell: 3.2;T-reg: 1.4" "Group enriched" "Detected in many" 6 "granulocytes: 2.5;NK-cells: 3.2;T-cells: 3.4" "Low region specificity" "Detected in all" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol "Secreted to blood" 14000000000 "Nucleoplasm, Cytosol" "HPA001251: , HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavourable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 45.8 17.4 2.6 18.1 3.8 0.0 82.0 1.4 2.8 36.7 24.5 2.4 11.2 5.0 27.2 66.8 38.1 33.3 46.7 49.5 1.9 1.8 27.5 370.2 25.3 46.8 3.5 2.0 103.5 11.4 1.4 6.3 10.3 4.6 47.8 15.3 17.7 12.8 13.2 16.0 10.7 14.4 53.2 6.2 35.1 19.8 39.3 1.9 2.3 30.6 20.7 15.1 46.8 83.8 0.4 0.0 2.5 0.4 3.2 3.4 0.8 0.1 1.5 0.1 1.3 177.7 90.7 0.1 19.9 78.2 23.7 48.2 0.2 0.3 0.0 0.6 15.6 0.2 1.7 0.8 3.3 1.8 0.1 0.0 0.6 0.6 34.2 0.1 0.2 105.0 0.5 10.8 0.8 0.4 0.0 2.5 3.1 0.0 0.8 0.1 0.8 0.1 1.1 0.5 0.1 0.1 0.9 0.0 0.3 14.4 0.4 0.4 0.0 0.0 0.0 5.6 0.9 26.1 0.1 0.1 0.4 0.0 8.1 0.1 0.8 0.0 0.4 2.0 1.6 0.1 2.0 0.0 1.4 3.4 0.0 0.4 2.8 2.9 2.5 3.2 0.0 0.0 1.4 0.8 2.6 3.8 1.4 2.8 1.9 1.8 3.5 2.0 4.6 1.9 C1RL "C1r-LP, C1RL1" ENSG00000139178 "Complement C1r subcomponent like" Q9NZP8 12 7089587-7109273 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 31.6;HSkMC: 35.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA011338, CAB026172" Supported Approved Microtubules,Cytosol "Secreted to blood" 5500000000 20000000000 Microtubules Cytosol "CAB026172: , HPA011338: AB_1847111" "prognostic favourable (7.92e-4)" "unprognostic (7.76e-2)" "unprognostic (3.91e-3)" "unprognostic (5.25e-3)" "unprognostic (2.92e-3)" "unprognostic (9.60e-2)" "unprognostic (2.75e-3)" "unprognostic (7.76e-2)" "unprognostic (1.22e-1)" "unprognostic (4.34e-1)" "unprognostic (9.58e-3)" "unprognostic (1.57e-1)" "prognostic unfavourable (1.52e-7)" "unprognostic (1.75e-1)" "unprognostic (5.74e-2)" "unprognostic (2.52e-1)" "unprognostic (2.26e-3)" 16.5 31.2 3.8 10.0 5.5 6.1 14.2 1.2 4.9 12.1 13.5 3.2 10.5 6.0 12.4 14.9 13.3 14.5 14.7 10.0 2.5 1.6 21.4 96.1 14.2 13.1 4.5 2.7 21.3 23.8 5.2 15.7 4.2 6.4 16.5 7.2 11.3 16.9 11.5 11.1 7.8 9.5 15.4 9.3 12.7 11.1 7.2 4.7 2.8 14.4 8.1 7.0 15.5 16.4 2.2 1.7 11.7 2.5 0.6 1.4 0.9 2.2 5.9 0.6 5.9 18.4 31.6 4.2 3.7 17.2 3.6 11.3 3.8 10.3 0.9 3.2 2.9 5.0 1.6 6.4 1.5 9.3 0.3 3.5 5.9 8.8 14.9 0.7 17.2 35.0 12.0 2.3 7.4 3.9 2.8 2.2 2.3 0.1 0.5 0.7 1.1 0.1 2.0 0.0 0.7 10.5 10.0 0.4 1.3 12.6 1.5 2.2 1.5 3.1 3.3 3.4 6.3 3.9 0.6 1.7 0.7 0.1 6.4 2.5 1.5 7.2 1.5 8.0 1.4 2.3 0.6 2.2 1.4 1.0 1.7 1.1 0.9 0.8 11.7 0.6 2.5 0.9 0.8 0.9 3.8 5.5 1.2 4.9 2.5 1.6 4.5 2.7 6.4 4.7 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 351.6" "Cell line enhanced" "Detected in some" "ASC diff: 97.0;ASC TERT1: 129.2;BJ hTERT+: 41.1;HSkMC: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 10 "neutrophil: 6.2" "Lineage enriched" "Detected in single" 17 "granulocytes: 6.2" "Low region specificity" "Detected in all" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" 93000000000 13000000000 Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favourable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavourable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 48.7 16.6 3.3 18.7 4.1 0.0 55.7 1.9 3.1 35.3 31.1 2.9 12.7 6.8 32.2 50.0 38.3 46.4 47.2 34.4 2.5 1.1 18.0 351.6 31.4 21.1 6.3 3.2 98.8 15.5 1.9 6.0 8.5 6.5 52.1 18.6 26.1 14.6 12.4 18.2 14.7 19.2 47.6 8.8 32.5 24.6 37.2 2.3 3.2 30.5 22.7 18.8 48.6 73.0 0.2 0.1 6.2 0.3 0.2 0.1 0.0 0.0 2.2 0.1 1.2 97.0 129.2 0.4 17.5 41.1 9.3 17.0 0.0 0.2 0.0 2.4 21.7 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.6 4.6 29.2 0.2 0.1 68.6 0.3 7.5 0.5 0.0 0.0 0.0 1.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.1 10.6 0.2 0.2 0.0 0.0 0.0 4.3 0.3 16.5 0.0 0.0 0.0 0.1 9.3 0.1 0.2 0.6 0.3 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.1 6.2 0.2 0.1 0.1 0.0 0.0 3.3 4.1 1.9 3.1 2.5 1.1 6.3 3.2 6.5 2.3 C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945672 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 132.7" "Group enriched" "Detected in some" 5 "Hep G2: 16.9;Karpas-707: 52.8" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "classical monocyte: 2.9;intermediate monocyte: 6.4;non-classical monocyte: 6.5" "Lineage enriched" "Detected in single" 8 "monocytes: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" CAB016775 Supported "Secreted to blood" 52000000000 "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavourable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" 9.2 3.2 0.9 4.8 1.5 0.8 5.0 1.2 1.3 2.0 5.3 1.8 1.6 2.5 2.0 4.8 1.9 3.3 3.2 5.4 0.8 0.8 13.1 132.7 19.4 13.1 1.2 0.3 2.7 2.1 0.8 2.8 7.6 1.7 1.8 4.3 2.9 2.4 1.5 0.7 1.6 6.6 3.5 1.8 12.1 1.9 2.0 1.0 1.8 1.2 0.8 3.4 2.7 1.5 0.2 0.5 0.8 6.5 0.1 0.3 1.2 0.1 0.0 0.0 0.2 0.0 0.0 0.7 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.6 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 16.9 0.3 0.0 0.2 0.9 0.1 0.2 0.0 0.0 0.1 52.8 0.0 0.0 0.1 0.2 0.1 0.0 0.0 1.3 0.6 0.0 0.0 0.1 0.1 1.0 0.1 0.0 0.1 2.3 0.1 0.1 0.2 0.2 0.0 0.2 6.6 1.0 0.2 0.3 0.0 0.1 2.9 0.0 0.1 6.4 0.1 0.1 0.1 0.1 0.5 0.2 0.3 0.2 0.8 0.1 6.5 0.0 0.1 1.2 0.9 1.5 1.2 1.2 0.8 0.8 1.2 0.3 1.7 1.0 C9orf3 "AOPEP, AP-O, APO, C90RF3, FLJ14675" ENSG00000148120 "Chromosome 9 open reading frame 3" Q8N6M6 9 94726701-95087218 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004633, HPA072729" Approved Approved "Cell Junctions" "Cell Junctions" "HPA004633: AB_1078362, HPA072729: " "unprognostic (4.25e-2)" "unprognostic (1.07e-3)" "unprognostic (6.29e-2)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (2.75e-2)" "unprognostic (9.59e-2)" "unprognostic (4.24e-2)" "unprognostic (2.99e-2)" "unprognostic (1.34e-1)" "unprognostic (2.60e-2)" "unprognostic (2.80e-1)" "prognostic favourable (6.33e-5)" "unprognostic (2.31e-1)" "unprognostic (2.56e-1)" "unprognostic (3.29e-2)" "unprognostic (3.37e-2)" 6.2 8.5 6.8 9.1 12.7 2.4 11.3 10.5 10.3 14.0 17.8 24.6 24.1 5.1 28.8 15.0 20.2 16.0 17.9 29.9 8.9 5.9 12.7 28.1 10.9 3.1 11.3 6.1 11.7 24.7 25.0 11.1 24.4 11.3 22.1 6.8 11.4 13.1 17.6 29.8 39.1 8.1 32.2 11.6 6.8 10.8 6.4 11.4 3.3 11.6 23.7 7.8 12.9 25.1 5.4 5.8 2.1 3.6 3.4 3.6 1.8 4.5 20.4 2.2 3.8 2.3 3.0 8.7 4.4 2.0 4.6 2.8 4.3 6.0 1.3 3.7 7.4 18.0 4.1 4.2 2.3 9.5 3.2 1.3 18.5 3.8 4.7 1.2 1.0 3.1 17.5 4.0 2.7 2.6 2.1 1.9 8.4 6.7 1.7 1.4 2.9 8.5 2.7 7.1 1.7 8.1 4.1 4.5 6.8 7.4 6.9 1.6 7.6 0.9 2.0 2.0 2.0 8.3 2.3 1.6 2.1 0.7 6.9 1.0 3.6 0.3 3.6 2.1 3.6 2.5 2.3 2.4 3.0 3.3 5.8 5.4 2.3 2.7 1.3 3.4 1.7 5.2 1.9 1.8 6.8 12.7 10.5 10.3 8.9 5.9 11.3 6.1 11.3 11.4 CA1 Car1 ENSG00000133742 "Carbonic anhydrase 1" P00915 8 85327608-85379014 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 156.0;intestine: 203.6" "Cell line enriched" "Detected in single" 1206 "HEL: 165.2" "Group enriched" "Detected in some" 10 "colorectal cancer: 3.4;stomach cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006558, CAB025790" Enhanced 7800000000 "CAB025790: , HPA006558: AB_1845989" "unprognostic (1.44e-1)" "unprognostic (7.56e-2)" "unprognostic (1.70e-1)" "unprognostic (3.57e-3)" "unprognostic (2.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.84e-2)" "unprognostic (2.03e-2)" "unprognostic (1.73e-2)" "unprognostic (6.12e-2)" "unprognostic (1.63e-1)" "unprognostic (1.04e-1)" "unprognostic (5.61e-2)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" 1.8 0.4 0.5 11.5 0.5 156.0 0.4 0.3 0.4 0.3 95.4 1.5 0.0 0.0 0.3 0.0 0.6 0.7 0.0 17.6 0.5 0.4 0.8 2.9 32.2 0.2 0.9 0.0 0.8 0.5 0.0 1.0 24.0 0.6 1.1 203.6 2.6 0.3 0.1 3.1 0.2 0.4 3.2 0.5 14.3 0.3 0.3 0.0 0.2 7.5 0.0 0.2 4.5 16.0 0.7 0.7 0.0 0.3 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 165.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 7.5 0.5 0.5 0.3 0.4 0.5 0.4 0.9 0.0 0.6 0.0 CA12 HsT18816 ENSG00000074410 "Carbonic anhydrase 12" O43570 15 63321378-63382161 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" Lyase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 103.5" "Cell line enhanced" "Detected in many" "A549: 38.2;ASC TERT1: 40.3;RT4: 40.5;SK-BR-3: 32.5;T-47d: 52.3;U-138 MG: 55.8;U-87 MG: 67.0" "Cancer enhanced" "Detected in all" "renal cancer: 109.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008773, CAB025181, CAB062549, CAB068179, HPA073203" Enhanced Approved Nucleoplasm,Vesicles 29000 Nucleoplasm Vesicles "CAB025181: , CAB062549: , CAB068179: , HPA008773: AB_1078394, HPA073203: " "unprognostic (2.01e-1)" "unprognostic (8.38e-3)" "unprognostic (3.47e-1)" "unprognostic (3.25e-3)" "unprognostic (2.73e-2)" "unprognostic (2.47e-2)" "unprognostic (7.48e-2)" "unprognostic (3.43e-3)" "unprognostic (2.29e-1)" "unprognostic (4.67e-2)" "prognostic unfavourable (3.80e-6)" "unprognostic (2.59e-1)" "unprognostic (1.51e-1)" "unprognostic (2.38e-1)" "unprognostic (6.56e-2)" "unprognostic (7.26e-2)" "unprognostic (1.21e-1)" 3.7 0.3 4.7 15.0 27.4 0.3 14.5 3.7 2.3 15.7 32.0 2.6 5.0 0.4 9.8 12.3 42.8 8.5 2.6 1.6 4.9 1.4 103.5 0.3 1.2 0.3 1.8 0.2 2.1 43.8 0.3 3.9 5.9 16.9 3.8 30.3 8.5 8.2 17.9 0.5 44.1 2.4 18.1 0.1 0.4 2.2 1.3 6.7 0.0 1.7 18.4 25.9 10.6 14.5 0.3 0.2 0.6 0.7 0.3 0.2 0.0 0.0 38.2 0.6 0.0 5.1 40.3 2.0 2.7 2.5 0.4 0.7 0.2 0.0 0.0 9.4 2.2 0.2 0.0 1.8 1.1 0.0 1.3 0.0 2.6 0.0 0.1 0.0 0.0 15.2 2.1 11.6 3.7 0.4 0.0 0.0 0.5 22.0 0.0 0.0 0.6 6.0 0.0 0.0 0.0 0.0 40.5 0.3 0.0 0.1 32.5 0.0 52.3 0.0 0.0 55.8 3.0 1.8 0.0 0.0 0.0 0.0 67.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.2 0.6 0.3 0.7 0.2 0.1 0.0 4.7 27.4 3.7 1.3 4.9 1.4 1.8 0.2 16.9 6.7 CA13 "CAXIII, FLJ37995, MGC59868" ENSG00000185015 "Carbonic anhydrase 13" Q8N1Q1 8 85220587-85284073 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.7" "Cell line enhanced" "Detected in many" "HEL: 16.1;RPTEC TERT1: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024689, CAB025567" Enhanced Uncertain Nucleoplasm,Nucleoli,Vesicles 100000 Nucleoli "Nucleoplasm, Vesicles" "CAB025567: , HPA024689: AB_1846004" "unprognostic (1.12e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (9.16e-5)" "unprognostic (2.21e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (7.90e-3)" "unprognostic (1.97e-1)" "unprognostic (1.34e-2)" "unprognostic (3.58e-2)" "unprognostic (3.13e-1)" "prognostic favourable (9.40e-4)" "unprognostic (7.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.00e-1)" 2.6 2.6 2.0 1.9 3.1 0.5 2.9 2.4 2.4 3.2 18.2 0.8 0.0 14.2 1.8 1.7 6.7 1.4 25.6 5.8 1.6 1.9 10.4 17.1 9.5 2.4 2.0 0.1 2.2 1.6 9.3 6.5 1.0 5.7 2.6 3.7 1.9 7.0 1.0 1.9 7.1 56.7 1.9 5.2 2.2 7.0 0.9 0.9 0.4 10.3 3.9 5.6 2.9 5.2 0.8 2.1 3.2 2.5 0.5 0.5 1.0 0.3 0.4 0.9 0.1 0.6 0.7 0.4 1.1 1.1 0.1 3.1 7.5 5.8 0.4 0.5 1.3 2.4 2.3 3.0 0.2 1.6 1.0 16.1 2.1 6.9 1.6 0.2 0.7 2.4 0.5 0.2 1.3 1.7 4.1 3.2 2.7 0.1 0.3 0.2 0.5 0.5 0.2 2.4 0.2 8.7 0.3 0.3 0.1 0.5 0.0 1.6 0.6 0.8 1.6 3.0 4.3 0.1 1.6 1.3 0.6 2.0 6.3 2.3 2.8 3.2 2.5 1.3 0.4 0.7 0.2 0.2 0.2 0.1 2.1 0.8 0.3 0.5 0.9 0.5 0.8 0.9 0.1 1.0 2.0 3.1 2.4 2.4 1.6 1.9 2.0 0.1 5.7 0.9 CA14 ENSG00000118298 "Carbonic anhydrase 14" Q9ULX7 1 150257159-150265078 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.9;retina: 29.4;seminal vesicle: 16.5;skeletal muscle: 24.1" "Group enriched" "Detected in some" 18 "AF22: 28.0;AN3-CA: 16.6;NTERA-2: 21.8;SK-MEL-30: 55.8" "Group enriched" "Detected in many" 7 "glioma: 4.9;melanoma: 23.2" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008482 Approved Approved "Plasma membrane" "Plasma membrane" "HPA008482: AB_1078395" "unprognostic (3.06e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (3.25e-2)" "prognostic favourable (8.47e-4)" "unprognostic (7.28e-2)" "unprognostic (4.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.47e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" "unprognostic (5.89e-3)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (5.80e-2)" 0.1 0.3 4.6 0.2 5.2 0.9 0.3 1.4 6.8 0.1 1.7 10.8 0.1 0.3 0.1 0.5 1.6 1.3 0.7 4.4 6.4 4.1 0.3 6.3 0.2 0.2 11.3 3.2 1.4 0.3 0.8 0.1 0.3 4.4 3.2 0.7 29.4 0.6 16.5 24.1 3.7 0.6 0.5 20.9 0.3 0.8 0.5 2.7 0.1 0.9 0.1 0.1 0.2 0.1 2.8 2.2 2.1 2.0 0.2 1.6 0.2 0.2 0.0 28.0 16.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 21.8 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 55.8 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.1 0.1 0.1 0.0 0.0 0.9 1.3 1.6 2.0 0.6 2.0 1.0 1.2 0.2 2.8 1.2 1.3 2.1 0.2 0.5 2.2 0.0 0.2 4.6 5.2 1.4 4.7 6.4 4.1 11.3 3.2 4.4 2.7 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463852-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Lyase "Disease mutation, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 108.1;stomach 1: 171.5" "Cell line enhanced" "Detected in some" "HaCaT: 33.1;HEK 293: 139.1;THP-1: 58.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 20.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001550, CAB010102" Enhanced 790000000 "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favourable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 1.6 2.2 24.4 21.5 32.6 32.4 6.9 4.3 23.2 1.3 108.1 28.9 42.0 46.9 0.9 2.2 5.6 0.9 33.0 4.3 29.1 14.5 53.5 43.0 10.2 1.3 49.0 14.2 0.5 9.1 3.1 2.0 3.5 65.0 0.8 105.6 7.0 14.0 54.2 9.2 13.3 7.6 6.0 27.5 2.5 171.5 5.1 58.3 0.0 3.8 2.4 1.1 1.0 1.4 1.9 8.0 20.3 8.2 0.0 4.4 17.5 0.5 0.3 1.5 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 1.9 0.1 0.0 1.2 0.0 33.1 4.8 1.6 0.0 0.0 139.1 4.3 2.4 0.0 0.0 3.0 0.6 0.0 8.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.4 0.0 2.7 0.1 0.0 0.4 1.1 0.0 0.0 0.7 0.0 0.0 0.0 58.3 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 20.3 3.1 4.4 0.1 8.2 4.4 0.6 0.0 0.4 8.0 1.9 0.0 0.0 6.8 0.0 7.1 0.8 0.0 17.5 24.4 32.6 4.3 23.2 29.1 14.5 49.0 14.2 65.0 58.3 CA3 "CAIII, Car3" ENSG00000164879 "Carbonic anhydrase 3" P07451 8 85373436-85449040 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "skeletal muscle: 347.5" "Group enriched" "Detected in some" 32 "HEL: 23.3;RH-30: 39.2" "Group enriched" "Detected in many" 7 "glioma: 23.1;prostate cancer: 9.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB004967, HPA021775, HPA026700" Enhanced 31000000 "CAB004967: AB_437014, HPA021775: AB_1845990, HPA026700: AB_1845991" "prognostic favourable (4.24e-6)" "unprognostic (1.40e-1)" "unprognostic (1.50e-2)" "unprognostic (2.22e-3)" "unprognostic (4.71e-2)" "unprognostic (8.43e-3)" "unprognostic (3.56e-2)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (3.68e-1)" "unprognostic (4.71e-2)" "unprognostic (3.54e-1)" "unprognostic (3.19e-2)" "unprognostic (1.18e-1)" "unprognostic (9.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.19e-1)" 18.0 0.4 0.2 0.1 0.2 0.5 0.6 0.2 0.1 0.5 0.3 0.0 0.1 0.1 0.6 29.0 9.5 1.0 0.2 1.3 0.2 0.1 0.2 0.2 4.1 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 6.6 0.0 0.0 5.5 0.2 347.5 0.3 0.4 1.4 0.1 0.1 0.3 0.5 0.0 0.0 0.3 14.1 3.4 0.7 0.5 0.5 1.8 0.0 0.0 0.0 0.8 0.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 23.3 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.8 0.0 0.2 0.2 0.2 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 CA4 "CAIV, Car4, RP17" ENSG00000167434 "Carbonic anhydrase 4" P22748 17 60149936-60170899 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease mutation, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.7" "Cell line enhanced" "Detected in some" "HEK 293: 1.4;HUVEC TERT2: 1.7;NTERA-2: 3.9;RPMI-8226: 1.5;RPTEC TERT1: 2.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "cerebellum: 50.1" "Cell type enriched" "Detected in some" 7 "neutrophil: 37.0" "Lineage enriched" "Detected in single" 370 "granulocytes: 37.0" "Region enriched" "Detected in all" 5 "cerebellum: 336.9" "Low region specificity" "Detected in many" "HPA011089, HPA017258" Enhanced Supported Vesicles 190000 Vesicles "HPA011089: AB_1845996, HPA017258: AB_1845997" "unprognostic (2.07e-2)" "unprognostic (7.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.78e-3)" "unprognostic (8.42e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (5.84e-2)" "unprognostic (7.76e-2)" "unprognostic (9.74e-2)" "unprognostic (1.54e-1)" "unprognostic (1.71e-2)" "unprognostic (2.68e-3)" "unprognostic (8.59e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-2)" 32.2 0.9 3.4 9.8 4.4 5.7 46.4 50.1 11.8 2.3 81.7 2.0 31.5 1.4 2.3 17.4 0.9 1.7 12.2 8.8 4.7 2.6 12.0 0.3 33.3 2.4 3.5 5.2 1.9 9.5 3.3 5.1 3.2 3.0 2.4 54.9 20.3 4.8 24.0 10.0 1.0 3.2 1.1 2.1 4.9 2.5 1.2 0.3 0.2 23.1 5.0 0.2 1.7 7.9 0.0 0.0 37.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.5 0.9 0.0 0.3 0.0 0.0 0.4 1.4 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.3 3.9 0.0 0.0 0.2 1.5 2.2 0.0 0.8 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.2 0.9 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.0 0.0 3.4 4.4 50.1 11.8 4.7 2.6 3.5 5.2 3.0 0.3 CA5B ENSG00000169239 "Carbonic anhydrase 5B" Q9Y2D0 X 15688830-15788409 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 15.4;fHDF/TERT166: 17.5;hTERT-HME1: 23.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012618 Uncertain Supported Mitochondria Mitochondria "HPA012618: AB_1846000" "unprognostic (1.62e-2)" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (1.55e-3)" "unprognostic (1.16e-2)" "unprognostic (4.59e-5)" "unprognostic (2.50e-1)" "unprognostic (6.89e-4)" "unprognostic (4.11e-1)" "unprognostic (3.89e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favourable (6.66e-6)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (8.94e-2)" "unprognostic (3.08e-1)" 9.3 4.6 10.6 4.9 11.1 4.1 10.2 3.1 7.8 28.7 3.6 11.5 1.4 2.2 9.8 3.7 8.1 9.5 9.1 6.5 9.9 8.2 10.3 7.8 7.3 8.8 12.2 6.7 15.2 4.4 16.8 4.4 3.9 13.1 6.2 4.7 29.5 8.3 6.2 2.0 7.5 4.1 9.4 7.1 5.3 5.4 23.0 8.1 2.3 8.9 10.9 11.6 6.3 9.4 4.3 3.5 2.7 3.6 7.9 13.3 7.0 2.7 1.6 1.9 3.1 5.8 15.4 1.1 2.9 3.7 2.1 3.1 0.8 1.8 0.8 3.0 17.5 3.0 6.8 3.3 3.8 0.7 3.2 1.5 2.1 0.7 5.7 1.9 3.3 3.6 3.5 2.8 23.0 3.1 0.7 2.0 10.1 1.5 1.5 1.5 0.7 12.2 0.9 1.4 1.4 3.3 2.0 1.7 3.6 4.0 1.4 2.6 2.0 1.9 4.2 2.5 1.7 13.6 1.6 1.5 1.5 0.8 2.8 3.8 4.7 2.7 3.0 0.3 13.1 3.6 11.4 3.6 13.3 12.3 3.5 4.3 9.8 8.3 1.7 7.9 2.3 0.5 10.0 7.0 10.6 11.1 3.1 7.8 9.9 8.2 12.2 6.7 13.1 8.1 CA6 ENSG00000131686 "Carbonic anhydrase 6" P23280 1 8945867-8975092 "Enzymes, Predicted secreted proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "salivary gland: 1237.9" "Cell line enhanced" "Detected in many" "Daudi: 5.3;U-2197: 4.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD8 T-cell: 15.4" "Lineage enriched" "Detected in many" 10 "T-cells: 15.4" "Low region specificity" "Detected in all" "HPA028550, HPA028692" Enhanced "Secreted to digestive system" 34000000 "HPA028550: AB_10600105, HPA028692: AB_10601883" "unprognostic (2.54e-5)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "unprognostic (2.90e-1)" "unprognostic (9.28e-2)" "unprognostic (2.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (5.93e-2)" "unprognostic (4.41e-2)" "unprognostic (4.29e-5)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-1)" 0.3 0.0 0.1 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1237.9 0.0 0.1 24.9 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.6 0.4 1.5 0.3 0.4 15.4 1.6 1.1 0.5 0.9 1.8 0.3 0.3 1.4 0.9 0.1 0.2 0.6 1.0 1.5 5.3 0.6 0.5 1.5 0.4 0.1 0.8 0.6 0.6 0.8 1.9 1.0 0.4 2.0 1.9 0.0 1.0 0.9 0.1 0.6 0.7 3.3 0.1 0.8 1.0 1.5 1.1 0.7 1.4 0.6 0.3 0.2 1.0 1.0 0.9 0.2 0.9 0.3 1.4 0.8 0.3 2.7 1.4 4.6 1.2 1.4 0.5 1.7 0.6 1.8 1.3 1.1 0.3 0.2 0.4 0.2 0.4 0.3 0.8 2.8 0.0 0.6 5.6 15.4 1.5 0.4 0.2 0.4 0.3 1.6 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 CA7 ENSG00000168748 "Carbonic anhydrase 7" P43166 16 66844379-66854153 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 37.2" "Cell line enhanced" "Detected in some" "CACO-2: 1.2;HAP1: 1.8;NTERA-2: 1.5;REH: 3.3;SCLC-21H: 2.7;THP-1: 5.5" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047237 Uncertain "HPA047237: " "unprognostic (8.77e-4)" "unprognostic (5.23e-4)" "unprognostic (1.57e-1)" "unprognostic (1.96e-2)" "unprognostic (2.19e-1)" "unprognostic (2.16e-2)" "unprognostic (7.90e-2)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "unprognostic (9.62e-2)" "unprognostic (1.69e-2)" "unprognostic (7.12e-3)" "unprognostic (8.47e-2)" "unprognostic (5.20e-1)" "unprognostic (1.90e-2)" "unprognostic (6.46e-2)" 0.2 0.2 3.2 0.4 7.5 0.2 0.2 3.9 7.7 0.2 37.2 0.3 0.0 4.8 0.3 0.9 0.3 0.2 0.2 0.2 6.3 0.5 0.2 0.2 0.2 0.2 0.7 2.9 0.2 0.2 0.2 0.0 0.2 1.8 0.2 32.0 0.0 1.1 0.4 0.2 0.2 22.8 1.0 0.1 0.2 0.2 0.5 1.3 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.9 3.3 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 7.5 3.9 7.7 6.3 0.5 0.7 2.9 1.8 1.3 CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673856-35681159 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "gallbladder: 70.4;pancreas: 47.4;stomach 1: 70.8" "Cell line enhanced" "Detected in some" "A-431: 39.6;HDLM-2: 20.7;U-87 MG: 83.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "cerebellum: 7.3" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in some" 4 "cerebellum: 13.8" "Low region specificity" "Detected in all" "CAB005100, CAB017107, HPA055207" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" "Plasma membrane" Cytosol "CAB005100: AB_2066539, CAB017107: , HPA055207: " "unprognostic (8.01e-3)" "unprognostic (1.34e-2)" "unprognostic (2.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.15e-1)" "prognostic unfavourable (1.71e-5)" "unprognostic (1.47e-2)" "unprognostic (3.90e-2)" "unprognostic (1.29e-1)" "unprognostic (6.24e-3)" "unprognostic (1.13e-1)" "prognostic unfavourable (2.22e-7)" "unprognostic (7.29e-2)" "prognostic favourable (9.50e-4)" "unprognostic (2.97e-3)" "unprognostic (8.67e-2)" 1.0 0.1 0.0 0.1 0.3 0.0 0.0 7.3 0.7 0.5 7.2 0.1 0.2 6.7 0.1 1.5 0.3 0.1 70.4 0.7 0.0 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.7 47.4 0.0 0.2 0.7 0.4 0.2 0.0 0.1 0.0 0.0 0.0 2.6 8.0 0.0 0.4 0.0 70.8 1.4 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 1.1 0.0 0.0 0.4 0.1 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.3 20.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.2 0.0 0.0 1.0 0.0 0.0 0.0 83.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.0 0.3 7.3 0.7 0.0 0.0 0.0 0.0 0.4 0.0 CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217390-27243943 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA057266, HPA069341" Supported Supported Nucleoplasm 26000 Nucleoplasm "CAB007781: AB_562057, HPA057266: AB_2683387, HPA069341: AB_2686125" "unprognostic (1.69e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.71e-3)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavourable (1.72e-11)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "prognostic unfavourable (1.82e-4)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.93e-3)" 12.0 11.9 10.1 23.1 12.4 11.1 18.9 13.3 13.1 14.6 12.4 10.9 9.7 12.1 21.0 18.0 16.3 16.6 15.8 9.8 8.6 8.8 13.1 22.9 13.0 27.9 11.8 9.5 24.4 18.1 10.7 16.4 10.6 10.1 12.5 11.6 12.9 11.7 18.3 12.3 26.0 13.2 17.3 12.5 18.7 11.4 21.3 10.8 35.2 13.8 14.1 18.5 12.7 13.1 5.1 4.9 0.8 2.3 3.7 7.9 2.6 25.2 22.9 10.2 20.4 16.6 13.7 8.1 10.7 7.5 13.6 9.7 25.9 10.1 22.6 9.7 9.8 14.3 30.0 14.2 10.2 14.8 24.2 32.3 17.4 13.5 8.3 25.4 16.3 10.4 11.7 19.7 22.5 14.5 22.7 12.6 11.9 25.4 16.2 37.8 24.5 17.4 28.4 30.6 23.5 10.0 12.9 20.5 10.3 15.0 10.7 12.5 8.3 10.7 13.0 20.6 17.0 16.0 21.5 26.2 16.9 46.2 8.3 24.5 17.7 0.0 1.2 0.5 4.7 2.3 4.0 5.1 6.5 7.7 2.7 5.0 4.3 4.3 0.8 3.7 1.2 4.9 7.9 2.6 10.1 12.4 13.3 13.1 8.6 8.8 11.8 9.5 10.1 10.8 CAMK1 CaMKI ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757342-9769992 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.5;blood: 59.4" "Cell line enriched" "Detected in many" 4 "HMC-1: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "eosinophil: 59.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 59.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol 550000 Cytosol "CAB031904: AB_630964, HPA051409: " "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavourable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" 27.1 60.5 28.0 11.7 26.0 3.5 34.1 12.4 31.2 9.5 10.7 4.4 5.8 6.8 12.6 10.5 7.1 12.6 8.9 10.2 21.4 14.0 13.1 20.7 9.2 10.4 10.3 19.9 21.5 4.5 7.4 7.9 5.1 10.1 18.6 8.1 6.8 5.1 15.1 4.7 3.3 8.3 18.4 7.2 7.1 8.1 13.4 5.6 0.6 7.0 3.7 10.4 9.5 10.3 0.0 3.2 59.4 9.2 0.7 0.4 0.9 0.1 3.6 2.9 0.0 15.1 5.6 7.3 8.6 4.8 9.9 9.4 5.3 0.6 0.2 2.0 5.8 0.6 0.0 1.1 6.2 0.1 21.1 11.6 6.9 7.4 8.4 1.0 92.0 5.9 0.9 13.9 1.5 8.3 1.5 0.2 3.7 2.2 0.0 8.5 2.0 5.7 0.0 0.1 0.2 5.9 0.6 0.9 3.7 1.5 0.1 0.8 0.9 14.9 4.3 4.5 5.6 6.4 10.8 0.0 0.0 0.2 9.6 3.3 0.6 3.3 4.8 59.4 0.0 9.2 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.2 0.7 9.2 0.1 0.4 0.9 28.0 26.0 12.4 31.2 21.4 14.0 10.3 19.9 10.1 5.6 CAMK1D CKLiK ENSG00000183049 "Calcium/calmodulin dependent protein kinase ID" Q8IU85 10 12349482-12835545 "Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 46.7;U-266/70: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 31.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007266 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA007266: AB_1078389" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-3)" "unprognostic (4.23e-1)" "unprognostic (2.32e-2)" "unprognostic (6.90e-3)" "prognostic favourable (1.67e-4)" "unprognostic (1.06e-1)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (7.40e-2)" "unprognostic (1.35e-2)" "unprognostic (6.55e-2)" "unprognostic (1.65e-1)" "unprognostic (4.66e-2)" "unprognostic (2.56e-3)" 5.1 5.3 20.9 10.5 22.1 6.6 4.0 23.4 33.5 8.3 11.5 4.6 10.0 3.8 3.3 3.3 8.7 4.3 6.8 13.8 18.6 7.2 2.2 11.5 7.6 9.3 5.8 17.8 2.6 17.0 1.3 2.5 3.2 5.0 4.9 12.9 11.9 4.5 15.4 1.7 18.5 5.5 5.6 4.9 10.5 3.4 6.2 6.8 20.8 13.6 2.9 12.5 8.1 7.0 7.1 4.2 31.8 3.7 1.4 2.3 1.3 0.1 2.5 2.9 0.1 1.8 0.6 0.2 0.4 0.9 0.6 0.9 3.5 2.0 1.4 0.3 0.2 1.3 3.5 0.5 0.5 46.7 1.8 5.6 8.3 0.2 0.5 0.1 5.1 0.1 2.3 1.2 0.1 0.3 0.1 0.2 0.7 2.9 10.9 2.2 1.9 1.1 8.3 1.6 2.6 0.1 2.7 4.5 2.0 5.5 2.0 0.0 1.5 1.3 0.1 2.4 3.6 7.7 1.6 21.5 6.7 4.7 3.6 3.6 0.0 8.3 2.2 31.8 1.8 3.1 1.9 5.6 1.6 2.3 4.2 7.1 1.9 1.3 13.9 1.4 3.7 1.4 0.5 1.3 20.9 22.1 23.4 33.5 18.6 7.2 5.8 17.8 5.0 6.8 CAMK2A "CAMKA, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290291 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "brain: 105.7;skeletal muscle: 50.1" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;SCLC-21H: 9.5;U-87 MG: 8.0" "Cancer enriched" "Detected in single" 13 "glioma: 6.0" "Group enriched" "Detected in all" 6 "amygdala: 60.7;basal ganglia: 50.6;cerebral cortex: 99.6;hippocampal formation: 74.6;olfactory region: 39.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "amygdala: 1311.6;basal ganglia: 698.1;cerebral cortex: 1576.4;hippocampal formation: 1569.1" "Low region specificity" "Detected in all" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Approved "Plasma membrane,Cell Junctions,Cytosol" 21000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB004330: AB_626788, HPA051783: , HPA051785: , HPA053973: " "unprognostic (7.20e-3)" "unprognostic (6.47e-3)" "unprognostic (6.16e-3)" "unprognostic (4.85e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-3)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (3.07e-1)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-8)" "unprognostic (2.71e-4)" "unprognostic (1.68e-1)" "unprognostic (1.70e-2)" "unprognostic (1.36e-3)" 1.3 1.7 60.7 1.3 50.6 1.3 1.1 1.4 105.7 1.8 1.3 3.7 0.0 1.2 2.1 1.4 1.9 1.7 1.3 3.7 74.6 10.5 1.6 1.2 1.5 1.2 5.1 39.8 1.3 1.1 1.1 0.4 1.3 2.4 1.6 1.3 0.0 1.2 1.4 50.1 1.6 1.3 2.5 1.7 1.2 1.3 1.2 2.3 0.0 1.2 0.0 1.1 1.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.6 0.0 0.5 1.3 0.8 0.7 0.0 0.1 0.0 0.2 0.6 2.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.2 0.5 0.2 1.7 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.0 0.0 9.5 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.1 0.0 8.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 60.7 50.6 1.4 99.6 74.6 10.5 5.1 39.8 2.4 2.3 CAMK2B "CAM2, CAMK2, CAMKB" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;heart muscle: 39.2;skeletal muscle: 70.7" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 41.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" 680000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: , HPA051785: , HPA053973: " "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 1.4 8.1 20.6 1.4 46.7 1.2 2.0 60.1 81.9 1.2 1.4 4.0 0.7 1.7 1.3 18.8 2.0 1.8 1.2 39.2 36.5 18.0 1.7 3.5 1.2 1.8 10.3 21.3 1.1 3.3 5.6 9.9 1.1 13.4 3.0 1.4 2.7 1.8 2.2 70.7 1.8 1.6 1.2 4.1 1.3 2.4 2.3 4.8 0.0 7.7 2.4 2.0 1.1 0.0 1.3 1.0 3.2 1.2 3.2 1.2 0.8 0.0 0.3 0.2 0.3 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.8 0.2 0.1 0.2 0.7 0.0 1.0 2.4 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 5.2 0.0 0.2 0.1 2.3 0.1 0.9 0.1 0.0 0.0 41.0 2.2 0.2 0.0 0.0 1.9 0.1 0.2 0.2 0.3 0.2 0.0 0.5 0.4 0.1 0.1 0.0 0.2 3.2 0.7 1.0 0.8 0.9 1.2 1.1 1.0 0.5 0.5 1.3 1.2 1.1 2.0 3.2 1.2 1.0 0.9 0.8 20.6 46.7 60.1 42.4 36.5 18.0 10.3 21.3 13.4 4.8 CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113451032-113761927 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" 140000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: , HPA051785: , HPA053973: " "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" 22.8 12.9 47.7 18.3 13.0 2.8 23.5 50.2 30.6 11.0 18.2 7.4 28.6 13.6 11.6 9.4 15.6 9.6 14.8 77.1 17.9 21.4 9.6 17.6 14.7 17.5 14.0 23.8 12.9 7.4 33.7 7.0 9.3 12.5 16.3 19.0 9.9 9.4 48.3 48.5 10.8 19.2 26.2 16.0 8.4 17.6 9.4 8.5 11.2 11.6 9.8 14.5 21.5 22.6 18.5 11.2 0.6 8.8 6.4 9.7 5.2 1.0 14.3 15.8 5.3 34.6 66.2 5.6 33.5 22.4 13.2 11.4 9.6 4.0 20.5 4.9 23.3 0.5 9.8 5.2 13.5 7.8 2.5 0.0 5.2 11.0 17.5 0.0 0.0 42.3 7.2 10.2 25.3 11.7 0.8 9.2 24.8 3.8 2.0 0.8 2.2 5.3 4.0 18.5 0.1 13.5 9.7 4.3 4.3 4.5 6.8 4.5 0.1 5.5 7.0 34.9 8.2 14.8 6.6 7.1 3.6 17.6 18.0 1.2 16.4 0.0 8.8 0.0 5.1 5.1 9.7 8.0 5.0 5.6 11.2 18.5 5.8 4.9 0.6 6.4 1.7 0.0 9.3 5.2 47.7 13.0 50.2 25.6 17.9 21.4 14.0 23.8 12.5 8.5 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.0" "Cell line enhanced" "Detected in all" "PC-3: 45.4;SK-BR-3: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" 170000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: , HPA051783: , HPA051785: , HPA053973: " "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 9.1 8.8 27.4 9.4 20.7 17.4 6.8 22.2 53.8 9.0 37.3 13.3 9.7 19.7 20.1 9.1 20.6 13.2 10.6 6.7 22.8 24.4 11.6 5.9 10.7 8.9 26.8 31.2 6.4 5.7 8.0 6.0 15.8 38.6 18.5 15.5 8.5 12.4 29.8 73.0 9.1 18.1 29.6 29.8 11.0 14.2 3.8 13.4 4.4 6.4 7.6 8.7 26.5 10.8 4.2 7.1 39.8 5.6 9.8 9.2 5.0 10.9 7.9 7.1 13.6 5.2 8.6 8.4 7.5 12.9 10.4 8.5 12.2 11.8 8.1 7.9 9.7 17.0 5.6 6.4 8.3 7.3 6.7 5.5 6.1 5.5 2.6 7.5 9.3 4.5 5.8 10.3 7.2 8.8 6.0 12.1 5.7 7.6 12.5 11.2 5.2 45.4 11.4 7.5 4.3 5.4 15.9 3.7 8.6 4.3 57.2 3.7 10.7 4.7 10.8 7.7 12.4 4.2 10.1 3.7 4.4 7.5 8.3 21.5 2.7 8.5 5.6 39.8 7.5 2.3 9.2 4.2 8.4 8.0 7.1 3.9 8.1 7.9 36.4 9.8 4.0 2.4 8.1 5.0 27.4 20.7 22.2 53.8 22.8 24.4 26.8 31.2 38.6 13.4 CAMK4 CaMK-GR ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.9;lymphoid tissue: 71.7" "Cell line enhanced" "Detected in many" "HDLM-2: 41.2;MOLT-4: 12.6;SH-SY5Y: 16.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 14.1;memory CD4 T-cell: 10.3;memory CD8 T-cell: 7.8;naive CD4 T-cell: 19.8;naive CD8 T-cell: 10.9;T-reg: 11.3" "Lineage enriched" "Detected in single" 26 "T-cells: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 1.1 6.5 9.5 6.4 34.2 4.6 1.0 48.9 16.5 1.8 2.3 1.0 0.0 2.4 1.3 0.8 1.4 0.9 2.7 0.9 5.9 3.2 1.4 2.5 1.9 12.0 2.3 6.8 1.4 0.9 0.3 1.3 0.6 3.4 5.8 2.5 0.1 1.7 2.6 0.8 0.9 3.8 1.5 2.0 4.2 2.6 13.8 6.6 71.7 1.0 0.0 8.1 2.8 1.1 0.7 0.0 0.4 0.0 0.6 19.8 3.4 0.0 0.0 1.4 1.0 0.3 1.1 0.0 0.3 3.2 3.8 3.7 0.0 0.0 0.0 2.0 0.1 0.1 3.1 0.3 2.8 41.2 2.6 0.6 1.3 0.0 0.1 0.2 0.1 0.1 0.0 8.0 0.8 0.6 0.0 1.5 0.2 0.0 12.6 0.0 1.9 0.1 1.9 2.4 0.1 1.4 0.0 9.1 16.1 0.5 0.0 2.7 0.0 0.2 0.0 7.8 4.6 0.0 6.9 1.3 0.1 0.0 3.8 0.0 3.0 0.0 0.0 0.0 2.8 0.0 14.1 0.7 10.3 7.8 0.0 0.2 19.8 10.9 0.4 0.6 0.0 0.0 11.3 3.4 9.5 34.2 48.9 15.1 5.9 3.2 2.3 6.8 3.4 6.6 CAMKK1 "CAMKKA, DKFZp761M0423, MGC34095" ENSG00000004660 "Calcium/calmodulin dependent protein kinase kinase 1" Q8N5S9 17 3860315-3894891 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.9;salivary gland: 27.1" "Cell line enhanced" "Detected in many" "HeLa: 17.8;U-87 MG: 20.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009111, HPA028062" Approved Supported Cytosol Cytosol "CAB009111: AB_2068406, HPA028062: AB_1845954" "unprognostic (1.39e-2)" "unprognostic (2.13e-1)" "unprognostic (8.66e-3)" "unprognostic (4.40e-3)" "unprognostic (2.94e-3)" "unprognostic (4.79e-2)" "unprognostic (1.98e-1)" "unprognostic (4.47e-3)" "unprognostic (8.23e-2)" "unprognostic (1.03e-2)" "prognostic favourable (2.65e-4)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (7.19e-2)" "unprognostic (8.70e-2)" "unprognostic (8.36e-2)" "unprognostic (3.10e-1)" 4.3 10.2 15.3 5.1 21.4 3.7 4.7 23.2 38.9 4.1 3.2 2.2 4.0 3.1 7.5 5.2 4.2 3.7 3.8 5.7 13.8 6.8 1.5 1.0 4.0 2.5 5.5 16.0 6.0 7.5 5.0 10.1 2.3 11.2 3.3 3.1 2.5 27.1 11.2 2.2 7.8 3.7 6.2 2.2 4.3 2.9 6.1 5.0 1.7 7.2 2.3 2.5 5.6 4.9 0.1 1.6 5.6 4.1 0.0 1.0 1.1 4.8 8.4 0.9 4.2 3.0 5.4 0.3 3.4 3.7 3.2 1.5 3.0 1.5 2.9 3.6 6.4 14.5 2.3 4.1 2.0 0.1 7.7 3.3 17.8 1.1 3.1 0.5 2.6 4.1 3.5 6.1 2.1 1.4 2.6 0.1 1.6 1.3 4.0 1.9 0.9 7.9 2.1 3.7 3.4 3.5 3.1 4.9 2.7 1.3 10.0 2.2 3.8 1.1 2.0 5.6 7.6 7.1 2.7 0.4 0.2 0.1 20.5 2.8 0.7 0.0 1.8 3.6 0.6 3.9 1.0 0.0 0.6 0.5 1.6 0.1 0.6 0.3 5.6 0.0 4.1 0.8 0.0 1.1 15.3 21.4 23.2 38.9 13.8 6.8 5.5 16.0 11.2 5.0 CAMKK2 "CAMKK, CAMKKB, KIAA0787, MGC15254" ENSG00000110931 "Calcium/calmodulin dependent protein kinase kinase 2" Q96RR4 12 121237691-121298308 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 125.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 125.5" "Group enriched" "Detected in many" 5 "classical monocyte: 14.2;eosinophil: 26.1;intermediate monocyte: 19.4;myeloid DC: 7.2;neutrophil: 17.2;non-classical monocyte: 16.5" "Group enriched" "Detected in all" 5 "dendritic cells: 7.2;granulocytes: 26.1;monocytes: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017389, HPA063713" Approved Supported Supported Cytosol Cytosol "HPA017389: AB_1845956, HPA063713: " "unprognostic (5.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-3)" "unprognostic (2.80e-2)" "unprognostic (1.93e-1)" "unprognostic (7.76e-2)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (4.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" 11.7 6.5 19.7 7.8 30.2 13.8 8.8 125.5 45.5 9.0 9.5 7.1 2.6 12.8 8.6 5.3 8.3 11.8 6.3 6.9 11.2 5.1 7.1 8.9 9.6 6.9 6.2 17.3 10.5 5.8 6.4 4.1 7.5 9.1 12.2 9.7 6.2 7.5 13.2 5.1 9.1 13.2 10.3 6.2 14.1 7.6 3.6 5.8 5.2 6.1 4.5 7.2 7.2 7.4 2.2 7.2 26.1 19.4 3.6 2.2 6.3 12.3 9.3 6.9 13.4 20.8 19.4 10.6 10.2 10.9 8.4 7.7 9.7 5.3 19.1 8.6 20.7 10.2 8.5 11.0 6.6 13.1 16.7 9.5 6.2 9.5 14.1 21.6 9.1 12.5 16.4 7.9 18.0 19.6 11.0 10.4 8.1 12.0 23.9 17.8 5.0 10.5 15.6 8.0 16.9 8.1 13.8 26.6 10.6 13.4 7.2 8.5 17.9 26.4 14.3 6.9 5.6 5.8 5.6 39.7 23.6 14.5 12.9 15.1 6.8 0.7 14.2 26.1 2.1 19.4 2.2 2.2 1.7 1.9 7.2 1.2 1.5 1.7 17.2 3.6 16.5 1.6 1.3 6.3 19.7 30.2 125.5 45.5 11.2 5.1 6.2 17.3 9.1 5.8 CAMKMT "C2orf34, CLNMT" ENSG00000143919 "Calmodulin-lysine N-methyltransferase" Q7Z624 2 44361950-44772592 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067912 Supported Nucleoplasm Nucleoplasm "HPA067912: " "unprognostic (2.28e-1)" "unprognostic (6.15e-2)" "unprognostic (1.96e-1)" "unprognostic (2.39e-2)" "prognostic favourable (9.10e-4)" "unprognostic (1.03e-1)" "unprognostic (9.58e-3)" "unprognostic (1.46e-3)" "unprognostic (1.85e-1)" "unprognostic (7.42e-2)" "unprognostic (8.76e-2)" "unprognostic (1.37e-1)" "unprognostic (3.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.66e-2)" "unprognostic (1.70e-1)" "unprognostic (8.57e-2)" 7.1 8.0 13.9 10.8 21.7 13.9 8.2 15.4 13.1 9.8 10.8 8.2 8.7 8.7 11.0 10.5 8.8 8.1 14.8 7.3 11.8 14.8 11.4 7.0 8.2 8.1 14.1 4.3 6.7 17.6 15.7 17.6 5.2 13.7 5.8 10.9 8.4 12.0 6.4 10.9 9.7 10.8 8.2 10.5 8.4 7.8 19.0 12.6 13.7 12.1 8.1 10.7 7.9 10.0 17.7 9.9 9.3 8.5 7.7 17.2 6.9 7.0 4.4 5.4 4.9 5.7 5.8 11.5 5.9 4.1 3.0 3.9 8.1 6.4 6.8 6.6 3.8 5.9 7.3 9.1 5.3 25.4 10.5 10.0 9.3 15.2 2.2 6.5 7.1 2.4 5.6 4.1 7.8 4.4 7.9 12.1 4.9 7.3 11.8 13.2 9.9 4.7 7.0 6.4 13.6 14.6 7.9 10.6 9.6 5.6 16.8 6.2 6.1 5.5 6.0 4.1 4.8 4.9 4.3 9.7 8.0 12.3 4.5 11.5 3.1 9.3 8.5 5.9 11.7 6.7 11.7 17.7 11.2 9.7 9.5 13.4 17.2 13.5 5.1 7.7 7.1 9.9 16.0 6.9 13.9 21.7 15.4 13.1 11.8 14.8 14.1 4.3 13.7 12.6 CAMKV "MGC8407, VACAMKL" ENSG00000164076 "CaM kinase like vesicle associated" Q8NCB2 3 49857988-49870222 "Enzymes, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "brain: 77.2" "Cell line enhanced" "Detected in some" "AF22: 5.2;HAP1: 6.9;NTERA-2: 24.6;RPMI-8226: 4.7;SCLC-21H: 8.4;SH-SY5Y: 5.4" "Group enriched" "Detected in some" 11 "glioma: 4.0;testis cancer: 5.2" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 12 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007656, CAB034931" Enhanced Supported Approved "Nucleoplasm,Cytokinetic bridge" Nucleoplasm "Cytokinetic bridge" "CAB034931: AB_2068550, HPA007656: AB_1078391" "unprognostic (9.47e-4)" "unprognostic (5.65e-3)" "unprognostic (1.42e-1)" "unprognostic (2.70e-7)" "unprognostic (2.76e-1)" "unprognostic (7.95e-4)" "unprognostic (3.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.48e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (8.11e-2)" "unprognostic (1.00e-3)" "unprognostic (7.61e-2)" "unprognostic (9.51e-2)" "unprognostic (1.67e-3)" 1.2 2.1 20.7 1.2 77.2 1.2 1.2 0.5 62.8 1.2 1.2 1.7 0.0 1.2 1.2 1.2 1.2 1.2 1.2 1.2 33.4 11.7 1.2 1.2 1.2 1.2 3.3 23.5 1.2 1.2 1.2 1.8 1.2 2.1 1.2 1.2 0.0 1.2 1.2 1.2 1.3 1.2 1.2 1.9 1.2 1.3 2.1 6.0 0.0 1.2 0.0 1.2 1.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.7 0.1 24.6 0.1 0.7 0.0 4.7 0.0 0.0 8.4 5.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 20.7 77.2 0.5 34.0 33.4 11.7 3.3 23.5 2.1 6.0 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991717-79009867 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced 2300000 "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavourable (1.41e-4)" "prognostic unfavourable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavourable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 13.8 15.3 9.6 13.1 10.2 8.1 13.0 12.2 10.8 17.7 43.8 12.3 25.4 25.5 12.0 14.3 27.5 10.0 19.5 10.8 9.0 6.9 10.3 17.7 11.1 11.5 12.5 7.7 10.4 14.7 13.1 11.8 33.0 12.0 36.7 41.5 7.9 30.3 41.4 9.0 8.9 27.2 8.0 12.4 18.1 25.8 19.0 10.3 14.1 12.4 8.9 14.4 10.3 13.7 4.1 3.8 17.5 4.4 3.1 6.2 4.4 26.4 29.0 8.1 11.7 7.7 9.2 10.4 16.3 14.3 17.6 14.9 13.7 25.0 6.4 9.6 11.4 13.4 6.9 12.9 17.6 10.6 12.6 8.3 8.8 11.4 6.6 7.9 13.1 9.5 8.3 16.2 8.8 30.3 10.4 10.9 11.7 14.3 12.0 4.7 5.5 30.9 6.7 13.3 7.2 7.7 13.3 11.7 11.7 8.7 57.8 12.3 71.4 9.5 15.1 26.3 23.8 11.8 20.4 12.9 10.7 6.2 16.8 6.1 16.4 6.1 3.8 8.1 6.2 4.4 6.1 4.1 4.6 5.2 3.8 2.9 4.5 4.4 17.5 3.1 2.9 2.7 3.8 4.4 9.6 10.2 12.2 10.8 9.0 6.9 12.5 7.7 12.0 10.3 CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 88.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol 28000000 Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavourable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favourable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" 22.0 15.6 9.6 23.8 11.6 18.2 18.8 17.7 20.1 25.8 33.3 8.4 23.0 25.4 19.3 30.2 86.9 28.1 39.1 21.4 8.8 11.2 27.8 21.3 19.4 19.5 10.8 9.7 21.4 24.9 13.3 14.1 38.1 16.8 27.3 17.0 15.8 39.7 24.3 24.2 38.9 49.9 16.5 7.7 21.3 20.7 8.3 6.7 32.1 37.5 50.2 53.7 33.7 35.2 16.7 22.8 34.5 24.8 15.7 19.6 28.5 47.4 25.3 7.2 16.1 13.2 16.7 22.0 14.1 22.5 16.6 12.7 16.1 42.7 11.9 23.6 26.8 70.2 9.4 59.6 5.3 12.6 7.5 28.3 14.6 15.7 13.1 6.6 39.8 18.4 32.1 14.1 6.9 28.5 16.8 9.6 13.6 30.5 13.1 21.0 20.9 22.9 13.0 7.4 7.2 22.6 88.3 13.0 9.6 14.9 57.7 13.6 24.8 13.1 24.7 13.0 8.9 27.6 6.3 5.9 4.3 14.1 22.6 8.1 14.0 34.3 24.8 34.5 19.6 23.7 15.7 15.6 15.5 17.7 22.8 16.7 9.1 12.5 15.8 15.7 14.0 17.9 16.6 28.5 9.6 11.6 17.7 20.1 8.8 11.2 10.8 9.7 16.8 6.7 CAPN10 ENSG00000142330 "Calpain 10" Q9HC96 2 240586716-240617705 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004170, HPA056098" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA004170: AB_1078381, HPA056098: " "unprognostic (1.05e-1)" "unprognostic (1.13e-2)" "unprognostic (9.29e-3)" "unprognostic (6.09e-2)" "unprognostic (5.44e-3)" "prognostic favourable (8.47e-5)" "prognostic unfavourable (4.78e-6)" "unprognostic (7.48e-3)" "unprognostic (7.94e-2)" "unprognostic (1.31e-2)" "prognostic favourable (7.94e-5)" "unprognostic (1.46e-1)" "unprognostic (1.11e-2)" "unprognostic (1.19e-1)" "unprognostic (6.88e-2)" "unprognostic (5.76e-2)" "unprognostic (5.58e-3)" 9.2 11.8 16.8 12.9 15.1 10.9 6.6 20.5 15.7 8.3 13.6 12.8 10.0 20.8 11.3 8.0 9.7 9.8 10.2 11.5 15.9 10.7 14.2 9.3 8.4 15.3 11.2 18.1 10.0 13.0 8.6 13.2 7.3 11.1 10.6 12.2 12.4 14.6 10.7 6.5 19.5 16.2 8.3 8.1 21.0 15.0 10.7 13.7 15.1 9.3 5.6 13.2 8.3 7.0 1.5 2.0 7.7 1.8 5.8 2.2 0.8 5.1 7.8 7.7 6.0 3.0 2.5 13.4 6.6 2.8 4.4 4.3 5.7 12.4 3.9 2.3 2.3 8.8 1.9 4.4 2.3 14.9 13.6 7.2 12.9 10.0 4.9 4.6 10.2 2.2 3.1 4.6 1.9 3.3 8.0 4.9 1.8 4.5 10.3 17.7 11.5 5.5 9.8 5.4 8.3 6.9 6.2 19.4 15.2 4.2 6.0 8.3 3.0 5.7 5.7 7.6 6.5 6.1 7.9 12.2 2.7 7.0 7.2 8.5 7.1 1.7 1.8 3.3 2.0 1.0 0.5 1.5 1.3 2.0 0.8 1.5 1.2 1.8 7.7 5.8 1.1 2.0 2.2 0.8 16.8 15.1 20.5 15.7 15.9 10.7 11.2 18.1 11.1 13.7 CAPN11 ENSG00000137225 "Calpain 11" Q9UMQ6 6 44158811-44184402 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 63.7" "Group enriched" "Detected in some" 5 "NTERA-2: 4.3;TIME: 10.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB018070, HPA030955" Enhanced "CAB018070: AB_2069481, HPA030955: " "unprognostic (2.20e-2)" "unprognostic (1.87e-1)" "unprognostic (1.64e-2)" "unprognostic (2.75e-1)" "unprognostic (6.22e-2)" "unprognostic (3.34e-2)" "unprognostic (3.99e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (8.96e-2)" "unprognostic (1.01e-1)" "unprognostic (2.13e-1)" "unprognostic (3.62e-6)" "unprognostic (2.38e-2)" "unprognostic (3.51e-1)" "unprognostic (2.27e-2)" "unprognostic (8.89e-2)" 1.1 0.3 0.1 0.2 0.1 0.2 1.9 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.2 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.6 0.3 0.2 0.1 0.1 0.0 63.7 0.1 0.1 0.1 0.1 0.2 0.2 0.3 0.4 1.2 1.3 0.1 0.1 0.8 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.4 0.4 0.0 0.0 0.0 0.3 4.3 0.0 0.7 0.2 0.4 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 10.8 0.5 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.1 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.1 0.2 1.3 0.1 0.0 1.2 0.0 0.9 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CAPN12 ENSG00000182472 "Calpain 12" Q6ZSI9 19 38730187-38769904 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood: 24.5;gallbladder: 21.0;liver: 21.8;salivary gland: 34.3" "Cell line enriched" "Detected in some" 5 "HMC-1: 17.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "pons and medulla: 2.4" "Group enriched" "Detected in many" 7 "basophil: 24.5;NK-cell: 12.7" "Group enriched" "Detected in many" 7 "granulocytes: 24.5;NK-cells: 12.7" "Low region specificity" "Detected in single" "Region enhanced" "Detected in some" "hippocampal formation: 3.6" HPA053322 Approved "Nucleoplasm,Focal adhesion sites" "Focal adhesion sites" Nucleoplasm "HPA053322: " "unprognostic (1.81e-1)" "unprognostic (4.48e-2)" "unprognostic (1.04e-2)" "unprognostic (1.08e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-3)" "unprognostic (7.20e-2)" "unprognostic (2.45e-2)" "unprognostic (1.29e-1)" "unprognostic (4.01e-2)" "prognostic unfavourable (5.90e-6)" "unprognostic (7.04e-2)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (4.59e-2)" 0.6 0.4 0.2 4.7 0.2 0.2 0.7 0.2 0.3 4.2 4.1 0.1 5.6 1.2 1.1 1.0 1.2 3.6 21.0 0.7 1.0 0.4 7.1 21.8 2.0 1.8 0.2 0.1 0.4 5.0 0.2 0.7 0.5 2.4 2.2 0.7 0.4 34.3 3.0 0.3 4.5 1.9 0.5 0.4 4.9 1.6 0.6 0.1 0.4 0.4 1.6 5.2 1.5 1.0 1.7 0.0 24.5 0.0 12.7 2.6 0.7 0.2 1.8 0.1 0.0 0.3 0.1 2.2 0.1 0.0 0.0 0.1 3.2 0.1 0.7 0.1 0.0 1.3 0.0 0.7 0.0 0.1 0.0 0.3 0.7 0.9 0.0 0.0 17.2 0.8 2.5 0.3 0.0 0.0 0.4 0.5 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 1.8 0.0 0.1 0.0 0.1 0.4 0.1 0.1 1.4 0.0 0.0 0.1 0.0 0.4 0.9 0.7 0.0 0.1 0.0 0.6 24.5 0.0 1.8 2.6 0.0 2.5 1.5 0.7 1.3 0.0 1.7 0.0 0.6 0.4 12.7 0.0 0.0 0.5 0.7 0.2 0.2 0.2 0.3 1.0 0.4 0.2 0.1 2.4 0.1 CAPN13 FLJ23523 ENSG00000162949 "Calpain 13" Q6MZZ7 2 30722771-30820542 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.3;pancreas: 20.4;stomach 1: 17.6" "Group enriched" "Detected in some" 5 "RT4: 8.8;SK-BR-3: 21.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA029496, HPA029497, HPA030034" Uncertain Approved Nucleoplasm Nucleoplasm "HPA029496: , HPA029497: , HPA030034: " "unprognostic (7.42e-2)" "unprognostic (1.19e-1)" "unprognostic (7.01e-3)" "unprognostic (1.96e-1)" "unprognostic (8.56e-2)" "unprognostic (1.51e-1)" "unprognostic (1.68e-1)" "unprognostic (1.32e-3)" "unprognostic (2.17e-1)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-1)" "unprognostic (1.96e-2)" "unprognostic (3.64e-1)" "unprognostic (3.32e-2)" "unprognostic (5.03e-2)" "unprognostic (4.28e-3)" 0.2 0.0 0.5 0.5 0.4 0.0 4.8 0.2 0.2 6.2 39.6 0.3 0.2 13.0 1.1 0.6 1.1 0.5 7.4 0.2 0.8 0.4 2.0 0.2 9.4 0.2 0.7 0.3 0.4 20.4 0.6 1.2 0.2 0.2 5.2 16.0 0.2 1.0 0.2 0.2 0.1 67.3 1.6 1.0 0.2 17.6 0.2 0.2 0.2 0.2 0.5 1.0 3.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 8.8 0.1 0.4 0.0 21.2 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.2 0.2 0.8 0.4 0.7 0.3 0.2 0.2 CAPN15 SOLH ENSG00000103326 "Calpain 15" O75808 16 527717-554636 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 15.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011960 Uncertain Approved Nucleoplasm Nucleoplasm "HPA011960: AB_10610556" "unprognostic (4.11e-2)" "unprognostic (1.63e-1)" "unprognostic (1.14e-1)" "unprognostic (2.66e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-2)" "unprognostic (1.54e-3)" "unprognostic (8.31e-3)" "unprognostic (1.32e-1)" "unprognostic (1.24e-1)" "unprognostic (1.86e-1)" "unprognostic (4.02e-2)" "unprognostic (2.53e-3)" "unprognostic (2.54e-3)" "unprognostic (5.91e-2)" "unprognostic (1.83e-1)" "unprognostic (9.23e-3)" 9.2 7.7 7.1 13.1 6.8 12.0 12.0 20.4 10.9 5.6 15.7 5.7 8.6 26.1 7.9 5.4 10.7 7.5 13.4 5.9 9.8 2.9 9.7 14.1 8.6 8.2 5.8 4.7 8.2 20.5 4.3 9.1 6.1 5.0 7.2 4.7 3.7 11.7 6.9 11.4 14.3 24.7 7.0 3.4 16.8 21.9 10.8 4.1 9.7 6.9 6.6 11.8 6.4 11.8 2.7 0.5 15.8 1.1 1.1 0.4 0.2 8.4 11.0 1.6 4.8 0.9 1.8 24.3 9.0 2.4 2.6 1.7 14.3 6.2 12.2 8.7 1.6 11.2 1.0 3.5 0.9 12.6 19.3 10.1 11.2 8.8 3.9 11.8 14.3 2.0 2.1 2.5 1.2 2.7 18.5 3.6 0.8 13.0 13.1 13.0 14.1 10.4 23.1 4.5 12.0 1.7 5.5 10.2 9.3 5.9 8.3 5.1 6.8 12.4 13.3 8.0 11.3 8.1 11.2 9.8 5.3 10.4 3.5 6.9 5.0 3.0 1.1 0.7 0.2 0.8 0.1 0.3 0.1 0.4 0.3 2.7 0.1 0.2 15.8 1.1 1.0 0.5 0.2 0.2 7.1 6.8 20.4 10.9 9.8 2.9 5.8 4.7 5.0 4.1 CAPN2 "CANPL2, CANPml, mCANP" ENSG00000162909 "Calpain 2" P17655 1 223701593-223776018 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024470 Approved Approved Supported Cytosol 1500000 Cytosol "HPA024470: AB_1845925" "unprognostic (2.77e-2)" "unprognostic (1.27e-3)" "unprognostic (2.03e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (3.32e-2)" "unprognostic (1.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.85e-1)" "unprognostic (1.96e-1)" "prognostic unfavourable (2.50e-4)" "unprognostic (1.21e-1)" "prognostic favourable (2.19e-4)" "unprognostic (1.61e-1)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "prognostic unfavourable (6.21e-4)" 56.2 41.0 23.8 20.7 22.2 11.1 61.1 26.1 20.9 40.3 44.8 18.3 23.3 14.5 29.1 44.5 56.3 40.1 58.9 33.0 26.5 13.1 41.6 13.3 58.6 18.2 27.4 18.2 32.4 26.8 53.7 12.7 26.4 23.8 27.2 44.4 16.5 62.5 31.9 48.1 16.5 22.7 35.7 32.3 15.9 48.2 17.2 24.7 5.0 29.9 39.7 35.9 28.3 38.8 9.0 41.6 1.7 29.1 6.0 28.7 28.2 45.7 29.3 9.4 6.3 31.4 43.6 9.0 43.3 62.9 31.5 17.9 23.2 36.8 0.0 14.3 48.0 28.6 10.1 68.4 29.3 11.7 10.5 0.8 15.0 2.9 28.2 2.4 1.5 23.3 22.2 49.0 26.2 62.4 13.1 12.2 92.6 0.9 0.1 2.1 5.2 38.3 3.8 30.7 0.7 54.3 2.7 2.0 10.9 22.3 60.9 13.5 9.2 11.0 95.9 29.5 24.5 25.4 55.5 3.6 6.9 0.1 73.9 5.1 32.4 1.7 29.1 1.7 28.7 19.5 24.5 9.0 20.0 27.7 41.6 3.6 6.4 17.4 1.5 6.0 17.5 1.9 19.9 28.2 23.8 22.2 26.1 20.9 26.5 13.1 27.4 18.2 23.8 24.7 CAPN3 "CANP3, LGMD2, LGMD2A, nCL-1, p94" ENSG00000092529 "Calpain 3" P20807 15 42359500-42412318 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.6;skeletal muscle: 210.9" "Cell line enriched" "Detected in some" 23 "SK-MEL-30: 75.1" "Cancer enriched" "Detected in some" 10 "melanoma: 9.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040052 Enhanced "HPA040052: " "unprognostic (1.06e-2)" "unprognostic (1.31e-1)" "unprognostic (4.00e-2)" "unprognostic (8.71e-2)" "unprognostic (1.53e-1)" "unprognostic (1.72e-2)" "unprognostic (2.11e-4)" "unprognostic (3.12e-3)" "unprognostic (2.82e-1)" "unprognostic (2.47e-1)" "unprognostic (2.37e-3)" "unprognostic (3.26e-2)" "unprognostic (3.91e-4)" "unprognostic (5.56e-3)" "unprognostic (2.43e-1)" "unprognostic (8.93e-3)" "unprognostic (1.38e-1)" 5.7 1.8 13.0 2.3 32.1 16.7 3.8 3.1 22.9 2.1 2.4 65.6 0.0 2.2 3.1 47.0 4.2 2.5 3.0 3.6 19.9 11.5 22.1 6.3 6.7 3.4 50.7 19.5 3.1 1.4 3.4 1.7 2.0 39.0 3.0 3.2 5.0 3.1 3.1 210.9 19.7 2.3 2.8 52.6 3.3 2.1 4.1 47.3 0.0 1.6 27.6 3.0 2.7 2.3 1.5 1.7 0.9 2.6 1.3 3.2 1.4 0.1 0.2 0.2 0.3 3.2 3.1 0.3 1.2 0.7 0.1 0.2 0.3 0.2 0.0 0.4 0.6 1.8 0.1 1.3 0.1 0.3 0.3 0.2 0.4 1.0 0.1 0.5 0.6 2.1 1.9 0.2 0.5 0.0 0.0 0.9 0.1 0.0 0.0 0.5 0.1 0.2 0.5 0.0 0.7 0.8 0.5 0.0 0.0 0.0 0.1 75.1 0.0 1.7 0.3 0.0 0.1 1.6 0.2 0.4 0.7 0.0 0.2 0.9 0.7 0.0 2.6 0.0 2.8 0.6 2.8 0.4 0.3 1.0 1.7 1.5 0.2 3.2 0.9 1.3 0.2 1.6 1.3 1.4 13.0 32.1 3.1 22.9 19.9 11.5 50.7 19.5 39.0 47.3 CAPN5 "ADNIV, HTRA3, nCL-3, VRNI" ENSG00000149260 "Calpain 5" O15484 11 77066932-77126155 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 49.5;intestine: 47.8" "Cell line enhanced" "Detected in many" "U-2197: 18.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 4.8" "Lineage enriched" "Detected in single" 5 "T-cells: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033237, HPA072319" Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB033237: AB_2069673, HPA072319: " "unprognostic (6.81e-3)" "unprognostic (1.31e-1)" "unprognostic (3.36e-2)" "prognostic unfavourable (2.16e-6)" "unprognostic (3.47e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-1)" "unprognostic (2.21e-2)" "unprognostic (5.35e-3)" "unprognostic (4.64e-1)" "unprognostic (3.17e-3)" "unprognostic (8.58e-3)" "unprognostic (3.25e-1)" "unprognostic (2.31e-2)" "unprognostic (2.30e-3)" 3.9 7.1 5.6 19.5 5.4 1.5 3.9 6.3 10.8 7.4 34.1 6.0 4.8 32.7 6.3 8.3 18.3 6.6 49.5 4.4 5.4 4.6 8.7 26.8 2.8 1.2 3.7 7.0 15.4 3.2 0.7 3.3 2.6 10.2 9.3 27.9 7.4 4.7 7.5 1.8 1.9 47.8 9.3 4.1 2.2 29.3 22.0 2.3 0.6 3.1 4.6 7.3 9.8 6.3 0.2 0.7 0.0 0.9 0.0 4.8 2.1 0.4 6.7 4.5 4.4 17.0 16.4 0.4 6.8 11.8 7.0 5.1 3.9 2.0 0.2 4.9 11.7 0.3 1.8 0.5 3.0 0.4 0.4 1.3 0.2 0.4 4.2 0.1 0.4 8.1 0.7 11.2 2.7 8.1 0.1 0.1 12.9 9.4 1.1 0.2 3.8 5.3 1.0 15.2 0.2 2.3 8.5 0.3 8.1 1.6 1.3 3.0 1.0 0.0 16.7 13.6 8.0 18.7 0.8 0.4 0.9 0.0 7.0 0.2 3.1 0.0 0.7 0.0 4.8 0.9 0.4 0.0 0.5 1.6 0.7 0.2 2.4 2.5 0.0 0.0 0.2 0.3 0.0 2.1 5.6 5.4 6.3 10.8 5.4 4.6 3.7 7.0 10.2 2.3 CAPN6 "CalpM, CANPX, CAPNX" ENSG00000077274 "Calpain 6" Q9Y6Q1 X 111245103-111270523 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 62.9;placenta: 173.5" "Cell line enhanced" "Detected in some" "HAP1: 3.5;HDLM-2: 11.0;NTERA-2: 17.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 25.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 1.2;plasmacytoid DC: 2.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA040259 Approved Vesicles Vesicles "HPA040259: " "unprognostic (1.27e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-2)" "unprognostic (5.77e-3)" "unprognostic (2.07e-1)" "unprognostic (9.93e-2)" "unprognostic (8.39e-3)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (9.45e-3)" "unprognostic (5.12e-1)" "unprognostic (6.25e-2)" "unprognostic (7.67e-2)" "unprognostic (6.50e-2)" "unprognostic (5.02e-3)" "unprognostic (2.66e-1)" "unprognostic (6.30e-2)" 1.7 0.0 0.2 1.7 0.2 0.0 6.0 0.3 0.3 3.9 4.2 0.2 23.4 0.2 18.2 62.9 2.4 2.9 2.6 0.4 0.2 0.0 5.1 0.4 0.3 1.1 0.2 0.4 1.9 4.1 0.0 0.2 173.5 0.3 3.6 2.2 2.1 5.6 21.7 1.7 1.0 1.3 2.0 0.3 1.0 7.2 2.8 0.2 0.5 1.7 4.7 2.9 1.4 2.6 0.1 2.0 0.8 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 17.3 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.0 0.1 0.0 0.2 0.2 0.3 0.3 0.2 0.0 0.2 0.4 0.3 0.2 CAPN7 PalBH ENSG00000131375 "Calpain 7" Q9Y6W3 3 15206152-15252918 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046617 Uncertain "HPA046617: " "unprognostic (2.70e-2)" "unprognostic (2.79e-1)" "prognostic favourable (4.85e-5)" "unprognostic (1.85e-1)" "unprognostic (1.69e-2)" "unprognostic (1.41e-2)" "unprognostic (2.22e-3)" "unprognostic (2.72e-1)" "unprognostic (1.42e-1)" "unprognostic (2.76e-1)" "unprognostic (1.39e-1)" "unprognostic (5.29e-2)" "unprognostic (1.12e-3)" "unprognostic (3.24e-2)" "unprognostic (7.84e-2)" "unprognostic (5.66e-2)" "unprognostic (1.05e-2)" 16.3 15.0 9.7 12.8 13.4 10.5 18.9 21.7 13.7 18.6 15.5 11.1 14.3 11.8 17.6 15.9 13.4 16.7 10.4 13.8 9.2 8.9 14.8 17.6 17.9 20.0 11.4 8.4 20.6 15.9 20.4 29.0 14.7 11.7 14.7 11.7 15.9 15.9 12.7 33.7 14.9 14.5 19.5 14.1 12.1 15.2 12.1 12.3 19.3 22.6 11.1 14.5 17.7 14.5 6.6 5.1 8.7 7.0 5.8 10.0 5.0 8.5 11.3 9.4 5.9 16.6 12.9 32.2 11.1 12.8 13.8 10.5 8.0 6.1 14.8 7.8 12.5 6.0 13.9 14.2 12.0 14.1 10.9 18.5 15.9 10.5 12.4 14.8 9.4 8.9 20.8 17.9 8.9 9.8 17.8 15.6 13.3 12.4 10.5 6.2 9.0 11.0 6.1 15.7 10.2 10.3 15.7 7.6 9.9 18.1 9.8 12.3 17.3 15.6 8.7 12.5 9.5 16.1 12.9 10.8 21.6 7.5 11.4 10.9 10.8 6.3 5.4 8.7 6.4 4.4 10.0 6.6 7.0 5.2 5.1 5.9 9.6 8.8 3.2 5.8 7.0 4.3 5.1 5.0 9.7 13.4 21.7 13.7 9.2 8.9 11.4 8.4 11.7 12.3 CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665734 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 32.0;stomach 1: 85.8" "Cell line enriched" "Detected in some" 9 "RT4: 41.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 28.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD8 T-cell: 1.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: " "unprognostic (4.87e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" "unprognostic (7.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.26e-1)" "unprognostic (8.08e-2)" "unprognostic (2.72e-3)" "unprognostic (3.55e-1)" "unprognostic (4.12e-6)" "unprognostic (6.95e-2)" "unprognostic (5.59e-2)" "unprognostic (3.83e-2)" "unprognostic (5.44e-3)" 0.2 0.0 0.5 10.3 0.3 0.0 7.5 0.2 0.3 1.0 7.9 0.6 0.2 2.2 0.3 3.3 0.6 0.4 32.0 0.2 0.2 0.1 2.5 0.2 13.0 0.2 0.2 0.2 0.2 8.0 0.0 0.2 0.8 0.2 4.6 9.9 0.2 4.6 0.3 0.3 1.5 4.0 3.2 0.2 0.2 85.8 0.4 0.2 0.3 0.2 1.5 1.2 15.1 3.9 0.4 0.0 1.1 0.0 0.0 1.4 1.5 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 2.4 0.0 0.0 0.0 4.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.9 41.1 0.6 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.9 0.7 0.0 0.0 0.1 1.4 1.1 0.0 0.0 0.0 0.0 1.5 0.5 0.3 0.2 0.3 0.2 0.1 0.2 0.2 0.2 0.2 CAPN9 "GC36, nCL-4" ENSG00000135773 "Calpain 9" O14815 1 230747384-230802003 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 17.6;lung: 19.8;stomach 1: 35.8" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 18.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 17 "naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 17 "T-cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020398, CAB033483" Enhanced "CAB033483: AB_1119945, HPA020398: " "unprognostic (2.64e-1)" "unprognostic (1.20e-1)" "unprognostic (2.60e-2)" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.49e-2)" "unprognostic (3.36e-2)" "unprognostic (2.30e-2)" "unprognostic (4.61e-2)" "unprognostic (3.44e-2)" "unprognostic (9.10e-2)" "unprognostic (1.60e-1)" "unprognostic (5.97e-5)" "unprognostic (1.51e-1)" "unprognostic (2.08e-1)" "unprognostic (4.60e-2)" "unprognostic (2.16e-1)" 0.2 0.7 0.4 7.0 0.3 0.0 0.2 0.3 0.5 0.4 10.4 0.4 0.2 3.9 0.2 0.2 0.7 1.5 12.7 0.2 0.5 0.2 0.2 0.2 19.8 0.2 0.6 0.2 0.3 0.2 0.0 0.6 0.2 0.2 0.8 13.7 0.2 8.1 0.2 1.3 0.0 17.6 0.2 1.1 0.2 35.8 0.2 0.2 0.2 0.2 1.0 7.1 3.7 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.1 18.3 0.0 0.0 0.6 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.3 0.4 0.5 0.2 0.6 0.2 0.2 0.2 CARM1 PRMT4 ENSG00000142453 "Coactivator associated arginine methyltransferase 1" Q86X55 19 10871513-10923070 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 64.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032961, HPA043561, HPA048073" Supported Enhanced Nucleoplasm "Intracellular and membrane" Nucleoplasm "CAB032961: AB_2068446, HPA043561: , HPA048073: " "unprognostic (9.46e-2)" "unprognostic (3.61e-1)" "unprognostic (2.94e-2)" "unprognostic (2.23e-1)" "unprognostic (2.69e-2)" "unprognostic (3.13e-2)" "unprognostic (1.66e-3)" "unprognostic (3.76e-2)" "unprognostic (7.81e-2)" "unprognostic (6.18e-2)" "unprognostic (9.31e-2)" "unprognostic (7.25e-2)" "prognostic unfavourable (7.88e-6)" "unprognostic (1.71e-2)" "unprognostic (6.26e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (8.37e-4)" 12.2 8.8 12.3 12.6 16.1 13.2 9.6 12.5 17.7 15.8 14.0 9.3 9.0 11.5 19.6 9.1 20.5 14.8 12.4 14.7 11.2 7.2 9.3 14.5 8.9 12.4 7.8 10.2 13.0 16.9 8.2 6.9 15.3 9.5 12.6 10.2 12.0 11.4 13.2 64.3 12.5 12.0 15.6 6.6 9.8 11.1 17.5 8.6 9.4 10.0 12.7 15.6 15.8 15.9 1.3 1.6 0.3 1.4 0.1 2.6 0.4 22.4 16.7 24.1 32.6 20.1 27.5 23.1 16.2 28.1 24.1 23.2 25.8 8.3 31.0 19.4 28.2 21.5 24.5 24.3 15.2 34.7 20.0 9.5 10.9 31.3 17.2 14.3 12.4 18.8 15.9 16.4 19.8 30.4 22.8 27.9 14.1 40.7 24.9 12.3 29.7 27.9 34.9 12.3 36.0 14.5 11.7 17.5 16.8 11.6 14.0 15.6 14.0 12.3 18.2 29.0 16.4 27.5 18.9 27.2 21.4 27.1 19.1 23.0 12.6 0.0 1.4 0.2 1.2 1.4 0.5 1.3 0.9 2.6 1.3 1.3 1.0 0.9 0.3 0.1 0.7 1.6 0.8 0.4 12.3 16.1 12.5 17.7 11.2 7.2 7.8 10.2 9.5 8.6 CARNMT1 "C9orf41, FLJ25795" ENSG00000156017 "Carnosine N-methyltransferase 1" Q8N4J0 9 74981020-75028423 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026756 Uncertain "HPA026756: AB_1845824" "unprognostic (1.59e-1)" "unprognostic (1.02e-1)" "unprognostic (2.99e-2)" "unprognostic (4.81e-2)" "unprognostic (3.48e-1)" "unprognostic (1.56e-1)" "unprognostic (3.22e-2)" "unprognostic (4.92e-2)" "unprognostic (3.94e-2)" "unprognostic (1.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.00e-1)" "unprognostic (1.85e-1)" "unprognostic (4.62e-2)" 7.7 8.3 8.0 12.9 17.5 8.4 8.5 22.9 11.6 11.3 13.5 5.7 11.3 14.6 10.0 10.7 15.8 7.8 10.9 7.5 7.6 6.0 14.9 20.2 7.3 10.6 6.3 7.9 8.8 16.5 16.1 12.5 7.6 5.4 10.7 10.5 7.7 13.9 12.3 9.6 10.2 23.3 8.7 6.6 9.9 9.0 22.1 8.6 15.1 16.6 8.7 11.0 9.7 12.8 3.5 1.5 2.1 1.7 3.1 4.7 1.4 14.4 8.7 3.7 9.5 6.1 13.0 13.6 12.8 5.5 5.1 4.7 2.2 9.9 22.8 6.9 9.5 14.4 11.2 14.0 14.6 19.9 8.6 11.6 8.9 10.1 7.4 21.0 11.5 8.8 7.1 9.6 10.0 10.2 9.8 20.6 9.9 3.9 15.3 5.9 17.0 7.8 7.4 11.0 13.8 13.5 10.4 3.6 1.9 9.8 26.1 4.9 13.2 6.4 8.0 8.4 10.9 10.0 11.2 14.7 18.7 6.9 13.1 14.6 5.3 0.0 1.0 2.1 3.2 1.7 4.5 3.5 3.2 4.7 1.2 1.9 3.6 3.8 0.4 3.1 1.0 1.5 4.1 1.4 8.0 17.5 22.9 11.6 7.6 6.0 6.3 7.9 5.4 8.6 CARNS1 "ATPGD1, KIAA1394" ENSG00000172508 "Carnosine synthase 1" A5YM72 11 67414968-67425607 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "brain: 88.7;skeletal muscle: 64.8" "Cell line enriched" "Detected in some" 12 "RPMI-8226: 12.8" "Group enriched" "Detected in many" 5 "glioma: 4.1;thyroid cancer: 10.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 20 "B-cells: 1.9;NK-cells: 1.3;T-cells: 3.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA038569 Enhanced "Intracellular and membrane" "HPA038569: " "unprognostic (1.07e-4)" "unprognostic (4.33e-3)" "unprognostic (2.00e-2)" "unprognostic (6.15e-2)" "unprognostic (9.45e-2)" "unprognostic (1.05e-1)" "unprognostic (7.28e-2)" "unprognostic (7.54e-3)" "unprognostic (1.29e-1)" "unprognostic (1.82e-1)" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (6.14e-6)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (3.83e-3)" "unprognostic (8.33e-2)" 2.9 1.3 9.2 1.5 24.3 1.5 1.2 3.0 23.9 1.3 1.4 88.7 0.0 1.5 1.2 2.5 2.0 1.5 1.6 5.3 19.7 10.2 1.2 1.3 1.5 2.1 36.9 14.5 1.4 1.6 2.0 0.4 1.1 30.6 1.8 1.3 0.0 1.3 1.3 64.8 1.3 1.9 1.3 51.1 1.8 2.1 1.1 28.1 0.0 2.3 0.9 1.6 1.1 0.3 1.9 0.1 0.0 0.0 1.3 3.2 0.9 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.2 0.3 0.5 0.7 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.8 0.0 0.2 0.0 0.0 0.1 0.4 0.1 0.1 1.0 0.6 0.2 0.0 0.1 0.1 12.8 0.0 0.0 0.1 0.2 0.1 0.8 0.1 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.9 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 2.9 0.0 1.4 1.7 1.0 3.1 0.1 1.9 1.3 3.2 0.0 1.3 0.0 0.0 0.7 0.9 9.2 24.3 3.0 22.2 19.7 10.2 36.9 14.5 30.6 28.1 CARS CARS1 ENSG00000110619 "Cysteinyl-tRNA synthetase" P49589 11 3000922-3057613 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737" Enhanced Enhanced Cytosol 110000 Cytosol "CAB075734: , CAB075735: , CAB075736: , CAB075737: , HPA002383: AB_1078399, HPA002384: AB_1846033" "unprognostic (9.10e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-3)" "unprognostic (1.43e-1)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "prognostic unfavourable (5.16e-4)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (8.00e-2)" "unprognostic (5.51e-2)" "unprognostic (2.45e-1)" "prognostic unfavourable (0.00e+0)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (3.46e-1)" 24.9 15.9 15.8 15.8 17.7 9.0 15.9 9.5 29.1 13.4 16.3 19.1 11.1 15.9 14.0 10.7 16.0 10.8 14.2 12.5 15.3 18.7 10.7 22.1 15.1 17.2 23.3 15.9 14.5 42.5 14.9 15.9 14.0 23.0 10.8 17.6 7.4 20.3 14.8 24.6 18.8 17.8 21.0 16.1 14.8 22.8 13.4 17.3 9.8 23.0 14.5 22.7 14.4 19.4 8.3 13.3 18.0 23.9 16.4 18.1 11.6 7.5 3.8 5.0 15.0 19.5 18.0 4.5 19.3 22.0 13.3 24.1 9.4 18.0 11.7 5.7 24.3 19.4 16.3 21.9 18.4 34.1 3.7 6.6 6.6 7.2 46.8 13.7 14.5 29.6 17.3 11.5 12.9 17.5 11.0 41.5 13.1 11.5 9.6 0.0 18.7 6.9 4.6 8.3 14.6 0.0 12.6 10.7 14.2 4.7 13.6 21.1 0.0 0.0 6.0 5.5 5.1 13.6 0.2 30.9 28.1 7.4 0.0 7.2 10.8 7.7 12.0 8.8 15.2 10.5 13.0 8.3 13.6 13.6 13.3 6.0 7.5 12.1 18.0 16.4 23.9 5.2 18.1 11.6 15.8 17.7 9.5 29.1 15.3 18.7 23.3 15.9 23.0 17.3 CARS2 FLJ12118 ENSG00000134905 "Cysteinyl-tRNA synthetase 2, mitochondrial" Q9HA77 13 110641412-110713603 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041776 Uncertain Approved Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA041776: " "unprognostic (2.34e-3)" "unprognostic (9.50e-2)" "unprognostic (6.62e-2)" "prognostic favourable (1.84e-4)" "unprognostic (1.98e-1)" "unprognostic (3.54e-3)" "prognostic unfavourable (1.21e-4)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (7.82e-2)" "unprognostic (2.11e-3)" "unprognostic (5.75e-2)" "prognostic unfavourable (2.49e-5)" "unprognostic (4.73e-2)" "unprognostic (3.42e-1)" "unprognostic (3.21e-1)" "unprognostic (1.71e-2)" 19.6 28.1 11.9 24.8 13.0 25.6 37.1 18.2 14.5 21.8 20.2 17.6 21.2 17.8 18.5 23.0 20.2 16.8 26.9 26.0 9.9 10.3 17.0 21.4 19.9 26.7 11.3 14.1 17.6 31.7 11.5 19.7 12.5 11.7 17.5 15.0 16.6 19.0 21.3 39.7 16.1 20.1 22.1 11.7 19.7 17.9 11.2 11.4 21.8 19.2 18.5 21.9 16.9 16.7 3.4 4.0 3.1 6.8 0.6 2.2 1.7 35.1 11.7 6.7 16.4 18.0 16.9 9.1 15.7 14.3 15.9 19.6 16.4 15.9 16.4 22.0 17.1 18.7 11.5 19.6 13.0 15.0 19.2 10.2 24.8 18.7 18.4 25.0 12.5 21.0 15.7 13.8 16.7 11.3 7.0 5.2 22.4 8.2 11.1 8.1 5.7 11.6 16.4 4.9 6.7 17.0 10.3 12.0 9.1 12.6 19.5 18.1 9.4 27.8 10.1 13.3 5.0 16.7 15.7 9.3 10.6 9.5 65.0 15.0 13.1 0.0 4.7 0.7 2.0 5.1 2.2 3.4 0.6 0.8 4.0 1.4 2.0 1.0 3.1 0.6 6.8 3.4 0.7 1.7 11.9 13.0 18.2 14.5 9.9 10.3 11.3 14.1 11.7 11.4 CASD1 "C7orf12, FLJ21213, FLJ21879" ENSG00000127995 "CAS1 domain containing 1" Q96PB1 7 94509219-94557019 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044404 Uncertain Approved Nucleoplasm Nucleoplasm "HPA044404: AB_10964353" "unprognostic (4.02e-2)" "unprognostic (4.16e-2)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (7.04e-2)" "unprognostic (7.90e-2)" "unprognostic (3.66e-2)" "unprognostic (2.18e-2)" "unprognostic (9.83e-2)" "unprognostic (4.74e-2)" "unprognostic (4.95e-3)" "unprognostic (2.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.01e-3)" "unprognostic (1.93e-1)" "unprognostic (7.07e-2)" "unprognostic (2.59e-3)" 8.6 21.6 16.6 7.1 24.2 4.1 13.2 20.5 24.8 10.0 13.2 10.9 7.5 5.0 11.7 12.5 5.1 9.2 8.1 13.6 25.9 22.2 10.2 7.1 9.0 9.2 13.1 16.6 14.1 7.8 12.7 22.8 9.8 20.0 11.8 15.9 8.4 22.6 8.2 11.3 3.7 6.3 9.7 13.7 8.0 6.0 10.1 11.5 7.3 13.2 2.9 8.3 9.0 6.3 1.8 1.1 0.2 0.7 1.8 4.7 0.7 3.0 5.8 20.1 7.4 6.1 7.4 3.4 4.1 7.3 4.6 6.0 3.7 7.5 7.7 10.8 5.5 1.7 5.0 1.4 9.1 12.3 4.0 6.9 5.0 6.6 5.2 11.3 0.0 6.7 5.3 4.2 6.0 7.2 3.7 17.0 11.2 4.4 15.6 6.4 10.2 4.7 10.8 16.3 6.0 9.2 8.4 7.6 26.0 6.4 12.0 4.0 3.1 7.1 3.8 11.5 9.1 9.4 5.9 16.3 15.2 16.1 6.3 2.6 7.4 0.0 0.6 0.2 1.9 0.7 4.7 1.8 2.8 2.3 1.1 1.7 2.9 2.2 0.0 1.8 0.6 1.0 1.7 0.7 16.6 24.2 20.5 24.8 25.9 22.2 13.1 16.6 20.0 11.5 CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923645 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 26.3" "Lineage enriched" "Detected in many" 11 "granulocytes: 26.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB001949: , HPA023857: AB_1846035" "unprognostic (6.30e-2)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-3)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (5.85e-3)" "prognostic unfavourable (6.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "unprognostic (2.85e-2)" 9.1 15.9 13.9 18.8 12.7 9.8 13.2 14.2 15.7 11.1 22.1 20.0 7.1 27.1 12.2 13.7 17.2 9.9 16.0 7.0 12.1 12.8 14.6 10.8 10.3 13.6 16.3 8.5 13.9 14.2 11.1 9.8 13.4 11.9 10.7 23.8 10.4 15.9 7.7 5.8 12.8 32.9 12.1 10.1 9.6 16.2 2.9 14.3 30.9 9.3 8.1 14.0 11.8 13.1 0.6 0.3 26.3 0.8 2.4 2.3 0.3 10.8 13.9 13.3 7.9 9.0 7.4 4.3 9.5 7.9 5.6 5.1 29.9 17.7 0.1 4.9 11.8 21.8 14.7 9.7 9.4 9.6 8.2 0.0 12.5 10.6 9.3 1.7 1.4 8.4 26.7 10.6 13.6 4.5 0.8 8.5 12.1 12.7 3.1 0.7 12.2 9.1 5.1 32.8 5.2 12.6 23.7 12.2 6.5 17.9 7.1 5.4 7.7 0.3 5.3 10.5 10.6 8.9 5.2 3.3 2.0 3.6 10.3 1.2 6.7 26.3 0.8 4.8 0.5 0.7 0.5 0.4 0.6 0.8 0.2 0.6 0.7 0.7 1.1 2.4 0.4 0.3 2.3 0.3 13.9 12.7 14.2 14.2 12.1 12.8 16.3 8.5 11.9 14.3 CASP1 "ICE, IL1BC" ENSG00000137752 "Caspase 1" P29466 11 105025443-105035250 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 64.2;lymphoid tissue: 40.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 37.8;HBEC3-KT: 17.9;HHSteC: 20.3;U-937: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enhanced" "Detected in many" "olfactory region: 22.8" "Low region specificity" "Detected in all" "CAB002685, HPA003056" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB002685: , HPA003056: AB_1846037" "unprognostic (1.21e-3)" "unprognostic (3.02e-1)" "unprognostic (9.47e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (6.67e-2)" "unprognostic (2.75e-2)" "unprognostic (1.35e-1)" "prognostic unfavourable (3.11e-4)" "unprognostic (9.03e-2)" "unprognostic (2.30e-2)" "unprognostic (3.18e-1)" "unprognostic (5.19e-2)" 7.4 3.9 6.6 15.1 17.0 8.2 6.9 3.5 7.0 4.1 12.8 2.2 2.9 34.0 3.0 4.2 10.6 4.3 7.3 4.9 9.3 3.0 6.4 5.8 20.5 16.2 16.7 2.6 4.4 3.4 0.2 3.7 8.7 13.3 6.1 13.9 3.7 7.0 3.2 1.6 9.9 37.2 5.2 17.4 40.7 5.6 1.5 11.0 4.1 3.7 5.6 9.0 9.7 13.2 7.3 39.6 40.5 64.2 11.1 34.3 31.2 0.4 0.1 0.0 1.8 2.0 4.2 0.3 1.9 37.8 4.8 13.2 0.0 0.2 6.1 0.7 2.1 2.7 0.0 17.9 1.1 4.0 0.0 0.3 0.2 0.4 20.3 7.1 0.0 7.2 12.7 3.9 10.4 2.0 0.0 0.0 1.1 0.0 0.2 9.9 0.0 0.1 5.9 0.1 4.8 0.1 2.9 0.1 0.1 5.6 0.3 8.3 0.4 16.4 2.4 4.4 0.2 0.4 0.5 0.0 1.7 0.0 2.7 44.7 0.9 12.3 42.8 23.2 25.4 64.2 34.3 7.3 18.1 22.0 39.6 6.0 9.9 16.4 40.5 11.1 64.0 1.4 22.2 31.2 6.6 17.0 3.5 7.0 9.3 3.0 16.7 2.6 13.3 11.0 CASP10 MCH4 ENSG00000003400 "Caspase 10" Q92851 2 201182881-201229406 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 42.4" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 17.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003780, HPA017059" Approved Approved "Golgi apparatus,Vesicles" "Golgi apparatus" Vesicles "CAB003780: AB_289592, HPA017059: AB_1846040" "unprognostic (4.01e-2)" "unprognostic (8.24e-2)" "unprognostic (4.80e-1)" "unprognostic (1.28e-3)" "unprognostic (4.74e-2)" "unprognostic (2.25e-1)" "prognostic unfavourable (8.54e-4)" "unprognostic (1.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.68e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" "prognostic unfavourable (6.05e-7)" "unprognostic (3.23e-2)" "unprognostic (2.19e-2)" "unprognostic (4.49e-2)" "unprognostic (1.38e-2)" 16.0 3.3 3.4 10.1 3.4 14.9 7.6 1.9 3.3 7.0 17.7 4.4 4.3 18.6 8.3 8.2 10.4 4.9 7.2 4.8 3.6 3.0 10.3 7.8 14.2 10.4 4.1 1.4 3.4 6.1 1.4 2.1 8.5 4.7 5.0 11.9 4.1 6.9 6.9 3.6 5.4 42.4 4.8 5.6 26.1 8.7 2.1 2.5 17.1 6.8 8.2 17.9 9.4 6.1 7.8 6.0 4.7 15.4 7.1 7.1 5.8 2.9 2.3 0.1 0.2 0.1 0.2 5.1 0.5 3.4 0.3 1.3 3.1 6.8 0.2 4.9 1.7 1.9 0.1 1.6 0.9 1.4 3.3 8.2 2.4 10.2 1.1 5.4 8.9 0.3 1.4 3.7 0.3 17.7 9.8 12.1 0.3 0.1 10.5 5.1 0.3 1.5 5.7 0.3 12.1 6.2 4.1 0.1 0.1 2.8 0.1 1.3 0.0 5.2 7.1 0.2 0.5 2.3 0.1 13.2 7.8 0.3 3.3 4.2 0.1 4.7 9.6 0.6 6.2 13.5 5.2 7.8 5.2 3.4 5.3 5.0 7.1 6.0 1.9 7.1 15.4 6.0 1.0 5.8 3.4 3.4 1.9 3.3 3.6 3.0 4.1 1.4 4.7 2.5 CASP14 "MGC119078, MGC119079, MICE" ENSG00000105141 "Caspase 14" P31944 19 15049384-15058293 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Hydrolase, Protease, Thiol protease" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 109.4" "Cell line enriched" "Detected in some" 7 "hTCEpi: 32.4" "Cancer enhanced" "Detected in many" "cervical cancer: 62.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010059, HPA027062" Enhanced Approved Nucleoplasm,Mitochondria,Cytosol 2200000 "Nucleoplasm, Cytosol" Mitochondria "CAB010059: AB_626800, HPA027062: " "unprognostic (1.17e-2)" "unprognostic (6.44e-3)" "unprognostic (6.22e-2)" "unprognostic (2.77e-1)" "prognostic unfavourable (7.59e-4)" "unprognostic (9.42e-2)" "unprognostic (2.19e-2)" "prognostic unfavourable (5.96e-4)" "unprognostic (2.68e-1)" "unprognostic (4.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.97e-1)" 0.2 0.2 0.2 0.0 0.3 0.0 1.9 0.2 0.3 17.9 0.2 0.0 0.8 0.0 1.1 0.3 1.2 0.1 0.0 0.2 0.3 0.2 0.4 0.3 0.2 0.0 0.2 0.0 0.1 0.3 0.0 0.2 0.5 0.0 7.7 0.0 0.0 0.8 2.7 0.3 109.4 0.2 0.0 0.2 0.1 0.2 1.6 0.0 2.3 0.2 0.9 0.0 0.6 4.0 0.8 0.5 2.3 0.6 0.1 0.6 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.8 0.6 0.4 0.4 0.2 0.4 0.3 0.6 0.4 0.1 0.8 0.5 0.4 2.3 0.1 0.2 0.5 0.6 0.0 0.2 0.3 0.2 0.3 0.3 0.2 0.2 0.0 0.0 0.0 CASP2 "ICH1, MGC2181, NEDD2, PPP1R57" ENSG00000106144 "Caspase 2" P42575 7 143288215-143307696 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012175, HPA050678" Approved Approved Nucleoplasm Nucleoplasm "CAB012175: , HPA050678: " "unprognostic (6.96e-2)" "prognostic favourable (7.38e-4)" "unprognostic (2.74e-2)" "unprognostic (7.51e-2)" "unprognostic (4.24e-2)" "unprognostic (2.39e-2)" "prognostic unfavourable (2.34e-4)" "unprognostic (1.74e-2)" "unprognostic (1.34e-2)" "prognostic favourable (2.89e-4)" "unprognostic (1.91e-2)" "unprognostic (1.64e-1)" "prognostic unfavourable (5.01e-6)" "unprognostic (2.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-1)" "unprognostic (1.64e-1)" 10.5 6.5 6.6 10.7 6.7 26.8 10.2 9.6 10.9 9.6 8.5 9.0 8.2 8.2 10.8 7.8 14.1 8.4 5.7 6.1 5.7 4.1 7.3 5.8 9.8 15.8 6.9 6.1 8.7 8.1 12.1 6.6 11.3 7.3 7.6 10.2 10.1 11.6 5.8 4.3 14.2 14.0 7.4 6.3 18.6 7.5 8.6 6.9 45.7 8.9 8.0 23.0 7.4 10.2 18.5 11.8 33.2 17.7 13.4 21.4 7.6 10.7 10.1 11.4 20.2 6.4 7.6 6.1 11.1 5.0 10.2 11.2 10.1 12.3 20.5 10.5 7.0 10.6 11.4 8.7 13.6 17.9 8.8 12.1 16.0 6.9 3.4 23.6 15.2 5.2 7.2 12.3 4.4 8.7 10.1 13.1 10.8 10.6 41.0 24.9 14.3 10.3 30.2 5.9 12.5 6.0 9.2 12.5 14.1 22.0 9.6 7.0 10.5 9.0 9.7 9.0 6.3 16.2 11.0 10.9 10.7 23.8 10.2 28.1 16.4 33.2 10.8 9.3 14.9 11.9 14.6 15.8 20.6 15.4 9.8 18.5 15.4 17.8 12.3 13.4 17.7 11.8 21.4 7.6 6.6 6.7 9.6 10.9 5.7 4.1 6.9 6.1 7.3 6.9 CASP3 "apopain, CPP32, CPP32B, Yama" ENSG00000164305 "Caspase 3" P42574 4 184627696-184649509 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 76.7" "Cell line enhanced" "Detected in all" "Karpas-707: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 76.7;eosinophil: 62.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000091, HPA002643, CAB008381" Enhanced Supported Nucleoplasm,Mitochondria 310000 "Nucleoplasm, Mitochondria" "CAB000091: , CAB008381: AB_590737, HPA002643: AB_1846048" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "prognostic favourable (2.24e-4)" "unprognostic (2.29e-3)" "unprognostic (3.58e-2)" "unprognostic (9.57e-3)" "unprognostic (5.86e-2)" "unprognostic (3.56e-2)" "unprognostic (1.12e-2)" "unprognostic (1.70e-2)" "unprognostic (2.41e-1)" "prognostic unfavourable (2.30e-5)" "unprognostic (1.41e-2)" "unprognostic (5.74e-3)" "unprognostic (1.30e-1)" "unprognostic (4.05e-3)" 20.7 11.6 10.8 16.9 10.5 16.7 10.0 22.3 9.2 10.4 25.4 12.8 12.5 32.3 13.9 11.5 22.8 8.9 12.0 8.8 10.0 8.8 10.6 18.7 12.4 23.6 10.2 8.5 8.3 10.0 4.6 13.6 29.4 9.7 8.8 20.9 8.2 13.0 10.0 12.6 9.5 49.7 9.3 12.6 26.5 18.7 6.4 10.9 44.7 7.8 13.5 24.3 16.2 11.0 4.2 5.2 76.7 10.6 9.2 9.9 7.0 8.2 4.6 18.3 8.7 11.4 15.2 10.6 24.8 18.8 17.4 10.1 8.3 6.9 11.5 3.9 12.1 7.0 14.5 8.8 19.9 29.4 7.9 18.3 3.6 19.3 13.6 14.9 17.5 20.7 10.8 11.0 9.0 21.5 15.1 72.7 17.9 3.5 23.5 13.9 18.1 5.8 17.0 8.6 11.0 15.0 13.5 10.5 11.4 10.7 9.8 13.9 5.3 9.7 14.6 8.0 7.3 5.9 11.4 33.8 31.7 7.9 9.7 10.4 11.3 76.7 4.2 62.8 5.5 6.8 5.7 4.2 5.1 7.8 5.2 3.1 3.9 5.8 5.8 9.2 10.6 4.1 9.9 7.0 10.8 10.5 22.3 9.2 10.0 8.8 10.2 8.5 9.7 10.9 CASP4 "ICE(rel)II, ICH-2, TX" ENSG00000196954 "Caspase 4" P49662 11 104942866-104969436 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "blood: 82.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA027588, CAB037167" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Cytosol "Plasma membrane" "CAB037167: AB_258864, HPA027588: AB_10603781" "unprognostic (1.19e-2)" "unprognostic (3.73e-1)" "unprognostic (3.44e-1)" "unprognostic (1.99e-2)" "unprognostic (7.19e-3)" "unprognostic (2.63e-2)" "unprognostic (1.26e-2)" "unprognostic (1.56e-2)" "unprognostic (5.31e-2)" "unprognostic (2.71e-1)" "unprognostic (2.38e-3)" "unprognostic (8.39e-3)" "prognostic unfavourable (3.27e-11)" "unprognostic (6.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-2)" "unprognostic (4.08e-3)" 10.6 6.3 0.5 9.7 0.5 6.1 9.4 0.0 0.0 4.7 3.5 8.9 3.5 5.9 14.1 5.8 7.3 4.9 0.5 0.5 6.7 16.5 14.0 10.5 1.0 7.5 16.8 0.0 3.0 10.7 5.8 4.0 11.2 1.9 1.6 10.4 8.8 4.3 2.0 19.0 8.2 0.2 4.2 11.3 8.2 8.0 20.5 29.3 82.8 43.2 29.6 35.7 46.8 6.3 2.1 0.0 2.8 13.7 31.2 5.3 11.0 21.5 17.7 24.8 5.3 29.0 3.3 23.7 14.2 10.6 0.0 19.0 16.9 3.7 0.1 8.6 1.6 13.8 33.6 8.6 4.2 28.3 28.5 21.1 29.5 30.7 0.2 0.0 13.5 0.6 5.0 10.2 0.0 6.3 3.8 4.1 2.9 14.8 10.1 0.1 0.0 10.1 7.2 10.0 2.9 12.6 15.9 18.7 6.5 16.4 7.7 0.0 0.0 0.0 9.5 19.7 13.0 14.9 39.1 7.0 31.5 43.2 34.6 20.5 24.2 30.1 29.3 20.0 14.8 22.0 82.8 29.6 33.5 4.9 35.7 46.8 CASP6 MCH2 ENSG00000138794 "Caspase 6" P55212 4 109688622-109703583 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 42.8" "Cell line enhanced" "Detected in all" "Karpas-707: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003775, HPA011337, HPA024303" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB003775: AB_562064, HPA011337: AB_1846053, HPA024303: AB_1846052" "unprognostic (1.07e-1)" "unprognostic (1.91e-1)" "prognostic favourable (2.64e-5)" "unprognostic (1.45e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "unprognostic (3.03e-3)" "unprognostic (9.87e-2)" "unprognostic (2.73e-2)" "unprognostic (2.59e-3)" "unprognostic (1.15e-2)" "unprognostic (6.78e-2)" "unprognostic (2.44e-1)" "unprognostic (8.74e-3)" "unprognostic (2.18e-1)" "unprognostic (2.41e-1)" "prognostic favourable (9.93e-4)" 8.1 6.1 3.6 6.7 4.3 5.3 14.3 2.8 3.8 6.9 25.5 2.8 4.5 23.4 5.9 4.3 8.7 5.3 11.7 4.9 4.0 2.0 11.0 14.3 5.6 8.5 5.0 1.6 7.0 13.0 2.3 6.4 4.3 4.5 8.1 19.5 3.4 8.0 10.3 3.4 6.5 42.8 14.0 6.6 9.1 9.2 2.7 4.3 14.5 11.2 3.3 8.4 8.2 12.7 4.4 8.0 8.5 7.0 5.6 21.3 8.0 12.4 4.0 8.3 7.5 6.1 6.0 12.3 7.0 4.8 6.2 6.8 6.7 25.6 1.3 8.1 7.1 5.8 9.9 11.0 5.0 19.7 6.5 10.9 3.6 5.9 4.9 10.9 7.7 6.6 8.2 6.0 1.5 11.8 14.1 38.8 10.1 7.0 28.1 6.9 6.3 7.3 9.8 5.3 6.8 20.6 11.8 8.8 6.6 7.4 13.3 4.1 5.7 4.0 10.0 6.9 7.4 3.3 7.9 5.7 10.3 1.4 9.0 13.1 3.5 8.5 5.3 6.3 4.9 4.8 5.3 4.1 17.8 9.3 6.0 4.4 21.3 11.8 1.1 5.6 7.0 8.0 16.4 8.0 3.6 4.3 2.8 3.8 4.0 2.0 5.0 1.6 4.5 4.3 CASP7 "CMH-1, ICE-LAP3, MCH3" ENSG00000165806 "Caspase 7" P55210 10 113679162-113730907 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 64.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB025563 Approved "CAB025563: " "prognostic favourable (2.11e-4)" "unprognostic (3.18e-2)" "unprognostic (2.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-3)" "unprognostic (3.96e-1)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "prognostic unfavourable (5.90e-4)" "unprognostic (5.45e-3)" "unprognostic (2.62e-1)" "unprognostic (2.86e-1)" "unprognostic (4.33e-3)" 16.5 7.8 8.6 12.3 8.7 3.4 22.1 4.7 11.3 13.3 35.5 5.9 9.8 30.8 12.6 6.1 12.0 9.5 7.8 9.0 7.6 3.9 14.1 15.7 16.2 12.2 7.3 2.7 11.0 18.4 5.7 9.6 10.2 9.1 11.9 28.5 5.8 21.8 10.5 9.7 10.9 64.8 9.3 12.4 12.3 21.0 4.3 8.0 12.0 8.4 8.1 11.3 10.6 36.6 9.6 8.6 14.6 17.1 5.4 12.2 7.4 10.8 11.7 9.6 5.1 17.6 15.5 6.7 12.6 19.7 22.5 28.3 8.7 18.8 11.5 7.5 11.4 9.6 11.8 9.5 16.0 17.8 15.9 7.4 8.7 14.5 11.8 7.9 9.8 10.0 6.4 12.8 5.3 29.7 1.9 15.7 8.3 14.6 18.7 6.2 1.7 7.2 19.1 39.1 6.9 17.8 8.0 0.7 5.7 9.7 14.1 6.6 16.7 7.0 14.2 5.0 9.6 5.2 10.3 11.6 7.3 0.3 5.1 14.9 5.6 14.6 12.5 9.4 9.6 17.1 8.4 9.6 8.3 12.2 8.6 7.3 6.5 8.7 2.1 5.4 14.0 1.1 11.1 7.4 8.6 8.7 4.7 11.3 7.6 3.9 7.3 2.7 9.1 8.0 CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201287711 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 52.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001302, CAB002047, HPA005688, HPA006191" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: " "unprognostic (5.21e-3)" "unprognostic (2.10e-1)" "unprognostic (1.83e-2)" "unprognostic (9.69e-3)" "unprognostic (2.09e-1)" "unprognostic (5.60e-2)" "prognostic unfavourable (3.02e-4)" "unprognostic (2.10e-1)" "unprognostic (4.79e-2)" "prognostic favourable (1.25e-4)" "unprognostic (7.75e-2)" "unprognostic (5.11e-2)" "prognostic unfavourable (1.27e-6)" "unprognostic (7.67e-3)" "unprognostic (2.43e-1)" "unprognostic (2.53e-1)" "unprognostic (4.53e-3)" 14.1 10.6 2.0 31.6 2.6 27.1 10.2 1.4 1.8 7.9 18.5 3.9 7.0 9.6 9.6 12.0 11.7 9.1 12.1 4.4 2.1 2.3 16.4 14.8 17.1 28.3 3.9 1.1 8.2 7.6 1.8 5.9 12.3 3.2 9.8 8.7 4.4 9.6 8.4 2.7 7.4 34.7 5.1 5.0 37.7 7.4 3.8 2.7 43.7 6.7 10.7 43.4 9.6 7.3 13.8 13.7 52.5 17.0 22.2 26.4 12.0 14.3 12.2 3.6 9.9 10.0 14.6 5.5 6.3 6.2 7.5 12.4 16.4 25.0 1.6 13.9 4.9 7.3 7.8 7.5 14.8 9.3 7.1 14.0 9.9 15.6 8.1 10.8 15.2 12.7 18.5 14.2 11.1 7.1 12.5 31.2 6.8 5.9 14.1 11.5 5.8 10.9 10.6 7.4 25.5 14.1 16.0 1.0 0.5 8.2 13.6 8.1 3.6 8.5 8.8 8.1 8.4 4.2 4.9 28.3 12.6 9.7 12.2 14.6 7.6 20.7 13.0 24.9 25.0 17.0 23.1 13.8 20.5 26.4 13.7 7.8 13.3 16.9 52.5 22.2 15.6 6.1 24.0 12.0 2.0 2.6 1.4 1.8 2.1 2.3 3.9 1.1 3.2 2.7 CASP9 "APAF-3, ICE-LAP6, MCH6, PPP1R56" ENSG00000132906 "Caspase 9" P55211 1 15490832-15526534 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001473, CAB004348, HPA046488" Approved Approved Mitochondria Mitochondria "CAB004348: AB_673489, HPA001473: AB_1078401, HPA046488: " "prognostic favourable (5.91e-4)" "unprognostic (2.42e-1)" "unprognostic (8.94e-3)" "unprognostic (7.84e-2)" "unprognostic (1.93e-2)" "unprognostic (8.54e-3)" "unprognostic (1.90e-3)" "unprognostic (6.75e-2)" "unprognostic (2.58e-1)" "unprognostic (1.29e-1)" "unprognostic (9.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.39e-2)" "unprognostic (2.35e-1)" "unprognostic (3.21e-2)" "unprognostic (5.48e-2)" "prognostic favourable (1.67e-5)" 7.4 24.1 7.8 8.2 9.3 8.9 5.5 11.1 8.7 8.3 9.3 10.2 18.9 5.2 11.9 16.5 7.5 13.4 29.1 10.2 8.3 7.2 11.6 9.4 10.8 12.6 10.7 4.3 33.4 29.0 15.6 18.5 14.7 8.8 10.2 6.4 8.7 6.6 19.0 8.2 2.8 13.3 7.8 9.0 11.0 6.7 14.4 7.1 6.2 14.8 7.2 14.6 7.3 8.1 11.2 11.7 23.3 11.2 13.0 5.1 6.1 7.1 10.4 4.1 7.1 9.3 4.6 3.7 5.2 6.9 7.8 10.0 7.3 8.6 10.4 12.3 7.1 2.5 6.8 5.5 9.0 3.6 8.5 7.4 23.2 7.3 8.7 7.2 8.7 6.3 10.2 11.9 3.6 8.3 16.7 9.7 4.6 3.6 2.4 8.2 4.0 5.8 4.8 10.2 12.1 9.6 4.1 3.5 6.8 7.4 1.8 12.3 4.4 5.2 3.3 10.4 4.8 11.2 3.4 9.4 14.1 11.7 7.9 7.8 3.4 22.7 11.2 23.3 5.1 8.2 3.7 9.6 3.0 3.6 11.7 11.2 1.7 2.6 16.0 13.0 7.9 5.2 2.8 6.1 7.8 9.3 11.1 8.7 8.3 7.2 10.7 4.3 8.8 7.1 CAT ENSG00000121691 Catalase P04040 11 34438925-34472062 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Mitogen, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 258.3;liver: 184.8" "Cell line enhanced" "Detected in many" "HL-60: 75.2;THP-1: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 13 "eosinophil: 258.3" "Lineage enriched" "Detected in all" 13 "granulocytes: 258.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001515, HPA051282, HPA055838" Enhanced Enhanced Vesicles 960000000 Vesicles "CAB001515: AB_384710, HPA051282: AB_2681419, HPA055838: AB_2682937" "unprognostic (3.62e-2)" "unprognostic (2.72e-1)" "unprognostic (3.59e-3)" "unprognostic (5.43e-2)" "unprognostic (4.44e-2)" "unprognostic (5.80e-3)" "prognostic favourable (9.67e-4)" "unprognostic (9.95e-3)" "unprognostic (3.22e-1)" "unprognostic (7.23e-2)" "unprognostic (3.34e-2)" "unprognostic (9.77e-2)" "prognostic favourable (1.96e-8)" "unprognostic (1.01e-1)" "unprognostic (7.31e-2)" "unprognostic (4.77e-2)" "unprognostic (6.59e-3)" 70.0 33.0 9.4 10.1 9.6 54.2 36.1 3.1 7.7 15.3 26.6 18.6 15.7 22.2 13.5 9.5 14.8 14.2 19.0 22.4 10.7 5.2 50.4 184.8 26.1 21.3 14.5 6.0 11.0 24.7 7.1 5.0 16.4 10.2 23.2 11.3 11.4 14.5 13.2 27.8 19.7 29.2 11.6 11.3 17.9 15.9 6.2 11.6 23.4 41.7 14.9 11.5 20.4 24.9 7.6 19.9 258.3 17.5 5.5 5.0 17.8 6.1 6.8 5.0 7.8 48.4 21.1 10.6 7.8 9.9 8.8 9.7 3.8 6.2 15.2 7.6 15.5 14.7 8.4 8.5 9.8 13.2 7.7 12.8 7.3 21.9 5.7 75.2 6.4 11.3 5.9 2.6 1.0 10.6 26.5 6.3 11.1 5.8 15.4 13.4 0.0 16.6 10.9 23.8 12.4 24.1 23.3 2.6 4.0 8.8 14.2 11.6 20.3 62.8 7.5 5.3 5.2 13.2 4.6 5.1 2.9 3.2 10.4 51.8 3.8 12.5 17.5 258.3 3.2 14.7 3.8 7.6 3.8 3.6 19.9 6.8 3.8 4.0 17.1 5.5 15.5 13.4 5.0 17.8 9.4 9.6 3.1 7.7 10.7 5.2 14.5 6.0 10.2 11.6 CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206276-119313926 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Supported Cytosol Cytosol "CAB004350: AB_2244054, HPA027956: AB_10601094" "unprognostic (2.52e-1)" "unprognostic (1.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.92e-1)" "unprognostic (4.10e-3)" "unprognostic (9.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (5.23e-2)" "unprognostic (5.21e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" 9.9 5.5 9.1 17.0 11.1 11.1 8.8 10.7 12.0 6.2 7.5 8.7 3.0 5.7 9.9 5.3 7.5 7.4 6.3 5.9 8.0 9.6 5.5 4.0 10.3 16.3 8.1 6.9 6.3 5.6 16.6 4.1 9.1 9.3 5.3 7.5 6.4 5.4 7.1 3.9 7.4 8.6 10.6 8.9 13.3 7.3 32.3 5.1 40.9 6.0 5.5 15.6 7.6 7.7 1.8 3.3 11.8 3.7 0.6 1.9 1.0 6.3 4.8 16.8 10.5 5.0 6.0 9.9 6.8 7.1 6.6 6.6 10.2 7.8 15.0 6.2 8.6 9.3 11.5 5.8 14.5 8.5 2.7 15.4 3.6 3.1 6.2 17.9 17.6 5.2 6.5 16.9 18.2 16.3 12.4 6.3 11.9 6.8 9.5 10.0 8.7 5.3 10.3 8.4 2.8 5.9 5.1 2.3 7.0 12.7 5.5 4.5 5.8 15.1 13.6 10.3 7.3 7.2 8.9 2.1 3.1 12.2 4.2 15.5 7.3 0.8 3.2 2.4 1.3 3.7 1.1 1.8 1.6 1.3 3.3 1.8 1.8 1.9 11.8 0.6 3.1 1.8 1.4 1.0 9.1 11.1 10.7 12.0 8.0 9.6 8.1 6.9 9.3 5.1 CBLB "Cbl-b, RNF56" ENSG00000114423 "Cbl proto-oncogene B" Q13191 3 105655461-105869552 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018327, HPA019880" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA018327: AB_1846097, HPA019880: AB_1846099" "unprognostic (2.65e-1)" "unprognostic (9.42e-2)" "unprognostic (1.72e-2)" "unprognostic (2.38e-1)" "unprognostic (5.89e-3)" "unprognostic (2.80e-2)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" "unprognostic (7.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.43e-2)" "unprognostic (8.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.20e-2)" "unprognostic (3.09e-2)" 38.4 9.0 3.7 19.5 4.9 15.5 16.3 24.4 3.8 13.7 18.7 5.9 7.7 9.3 13.8 12.2 8.3 12.5 13.4 27.5 3.8 4.8 7.4 6.7 16.3 19.1 4.4 1.9 17.7 6.8 3.4 13.5 25.4 7.9 12.9 8.0 11.6 9.1 6.3 10.3 8.5 13.8 25.6 5.7 16.4 12.4 9.2 5.2 11.6 13.5 7.0 18.0 24.9 24.1 5.1 3.1 2.8 2.1 10.3 9.9 1.6 1.6 2.2 7.6 3.7 8.7 8.8 4.9 5.6 2.8 1.6 2.7 2.9 1.9 3.6 4.0 3.0 2.8 1.0 1.0 2.0 2.7 2.9 1.9 11.7 1.8 12.8 1.3 1.4 8.4 3.0 4.4 12.0 5.5 2.0 11.5 3.5 2.0 1.9 0.9 2.7 3.2 4.1 2.3 0.6 4.0 7.2 5.8 6.4 6.7 0.8 8.8 1.6 2.9 3.1 23.4 2.0 3.2 1.3 6.5 0.5 5.6 6.2 1.2 1.5 0.7 1.5 2.8 9.9 0.9 8.8 2.2 5.1 5.6 1.3 5.1 4.4 8.0 1.0 10.3 2.1 3.1 5.6 1.6 3.7 4.9 24.4 3.8 3.8 4.8 4.4 1.9 7.9 5.2 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800634 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 66.8" "Cell line enhanced" "Detected in some" "A-431: 19.0;BEWO: 13.1;CACO-2: 12.8;CAPAN-2: 26.3;HaCaT: 18.4;HBEC3-KT: 16.0;hTCEpi: 12.2;RT4: 16.0;SK-BR-3: 14.6;T-47d: 10.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm Nucleoplasm "CAB008087: AB_2228531, HPA035266: " "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favourable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.0 0.5 8.5 0.2 0.0 4.8 0.1 0.4 4.4 39.5 0.1 3.2 29.5 1.7 1.7 22.0 1.4 18.8 0.1 0.6 0.0 4.9 15.1 1.3 0.1 0.1 0.3 0.8 18.1 0.9 0.7 4.1 0.2 6.9 6.9 0.5 11.4 5.2 0.1 20.8 66.8 0.4 0.1 0.1 10.2 1.6 0.1 0.5 1.9 13.2 15.7 7.6 8.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 19.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 12.8 26.3 0.0 0.0 0.0 18.4 0.0 16.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.0 0.1 0.0 0.0 14.6 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.4 0.6 0.0 0.1 0.3 0.2 0.1 CBLL1 "FLJ23109, HAKAI, RNF188" ENSG00000105879 "Cbl proto-oncogene like 1" Q75N03 7 107743697-107761667 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021773, HPA026699" Enhanced Supported "Nuclear speckles" "Nuclear speckles" "HPA021773: AB_1846103, HPA026699: AB_1846104" "unprognostic (1.90e-2)" "unprognostic (2.25e-1)" "unprognostic (8.57e-2)" "unprognostic (3.79e-2)" "unprognostic (8.16e-2)" "unprognostic (7.20e-2)" "unprognostic (1.37e-2)" "unprognostic (3.96e-3)" "unprognostic (4.28e-2)" "unprognostic (2.16e-3)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-3)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" "unprognostic (1.09e-1)" "unprognostic (8.71e-2)" 15.8 12.0 11.7 13.6 20.0 38.8 16.8 18.7 19.4 15.3 17.2 19.2 11.6 10.8 22.9 9.7 14.4 14.2 10.2 11.5 11.9 10.7 11.6 12.5 12.9 16.5 12.6 14.3 18.2 15.5 14.5 17.2 13.5 16.5 18.7 13.0 14.7 12.8 19.6 32.6 16.6 14.4 16.2 15.1 15.8 14.7 21.1 13.3 29.0 15.8 11.8 19.3 17.6 12.7 17.9 16.7 32.2 15.7 23.4 40.3 20.1 13.5 15.5 12.0 15.3 11.0 9.6 8.2 10.2 10.6 11.5 11.4 10.4 13.8 19.6 14.8 11.5 9.6 16.6 12.4 15.8 13.9 10.5 16.0 11.4 8.7 12.8 23.5 15.7 10.0 11.5 15.5 17.0 11.8 25.1 16.7 11.0 23.1 32.1 16.0 17.2 10.6 14.9 13.0 20.3 8.7 12.5 12.8 20.0 15.2 22.4 11.1 7.5 12.0 11.5 17.9 12.9 16.9 15.6 27.2 29.5 31.8 11.0 14.7 15.1 32.2 14.2 23.3 19.0 14.7 28.0 17.9 30.1 21.8 16.7 17.4 20.9 19.6 21.9 23.4 15.7 9.0 40.3 20.1 11.7 20.0 18.7 19.4 11.9 10.7 12.6 14.3 16.5 13.3 CBR1 "CBR, SDR21C1" ENSG00000159228 "Carbonyl reductase 1" P16152 21 36069941-36073166 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 176.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA018433 Enhanced Approved Nucleoplasm,Cytosol 12000000 Nucleoplasm Cytosol "HPA018433: AB_1846109" "prognostic favourable (2.18e-4)" "unprognostic (9.78e-2)" "unprognostic (3.25e-2)" "unprognostic (2.14e-1)" "unprognostic (6.47e-3)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (6.37e-2)" "unprognostic (4.56e-2)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (4.00e-1)" "prognostic favourable (4.75e-4)" "unprognostic (2.37e-1)" "unprognostic (2.47e-1)" "unprognostic (6.13e-3)" "unprognostic (2.47e-2)" 9.6 22.9 31.7 8.4 41.6 3.7 8.5 12.0 35.8 14.6 63.4 75.9 6.5 176.1 9.3 17.1 40.2 9.6 15.1 7.8 37.7 24.7 35.2 77.2 11.7 8.5 57.3 25.2 10.4 8.0 8.9 7.9 11.7 51.6 16.7 16.8 10.4 23.1 15.0 8.7 34.4 118.1 11.6 48.1 10.0 41.4 5.7 41.9 3.6 11.3 29.8 14.3 12.4 17.1 17.0 29.9 17.1 51.4 19.1 29.2 37.0 25.4 39.2 4.8 12.4 25.2 25.5 0.2 28.5 20.5 15.6 18.7 14.4 15.0 6.4 18.8 26.6 18.7 9.8 28.0 12.0 31.6 23.2 19.2 22.8 9.8 14.4 10.6 17.7 12.4 35.3 15.1 6.6 16.6 0.0 4.7 14.3 25.2 5.3 11.1 0.0 28.6 0.0 0.1 17.7 41.5 12.7 14.0 12.6 27.6 40.1 32.4 19.0 14.8 16.7 17.5 7.4 44.5 20.6 32.1 58.1 0.1 32.2 10.6 25.4 1.8 36.6 17.1 18.1 51.4 15.3 17.0 22.7 16.9 29.9 15.6 29.2 21.4 2.5 19.1 38.6 10.4 22.7 37.0 31.7 41.6 12.0 35.8 37.7 24.7 57.3 25.2 51.6 41.9 CBR3 SDR21C2 ENSG00000159231 "Carbonyl reductase 3" O75828 21 36134912-36146566 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 68.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 11.9;NK-cells: 4.9;T-cells: 17.9" "Region enhanced" "Detected in many" "basal ganglia: 43.6" "Low region specificity" "Detected in all" HPA018434 Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA018434: AB_1846110" "unprognostic (3.64e-3)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.22e-2)" "unprognostic (6.12e-2)" "unprognostic (2.98e-2)" "unprognostic (3.75e-1)" "unprognostic (9.10e-2)" "prognostic unfavourable (5.95e-6)" "unprognostic (3.13e-1)" "unprognostic (1.80e-1)" "unprognostic (3.99e-3)" "unprognostic (1.94e-1)" 9.2 1.5 5.4 3.0 13.9 0.9 12.2 3.1 4.7 8.6 3.8 1.4 4.1 2.4 5.5 8.8 27.6 4.1 4.9 4.9 3.6 2.9 1.6 0.4 3.5 3.4 3.8 6.1 9.3 1.2 0.3 1.2 2.2 2.5 7.2 2.9 3.3 21.8 4.2 2.4 16.3 2.6 10.5 2.3 1.5 2.7 4.3 2.7 0.9 2.3 68.2 14.1 7.1 8.0 11.9 1.2 0.4 0.5 4.9 17.9 6.2 12.0 3.4 1.5 3.0 11.8 18.3 2.3 13.2 15.6 15.1 12.1 0.1 2.6 0.0 3.9 13.5 5.6 2.0 2.6 6.1 16.4 6.3 0.5 3.6 0.1 1.0 0.0 0.0 2.6 0.3 10.5 1.3 9.1 0.0 0.1 4.4 9.0 1.1 5.3 1.2 15.3 2.5 2.9 23.4 5.0 5.1 0.8 1.1 10.1 12.3 19.2 3.6 1.4 6.2 9.8 0.8 11.0 12.7 0.5 0.2 0.0 10.2 0.3 17.6 0.0 0.3 0.0 1.2 0.2 1.5 11.9 13.0 4.0 1.2 10.6 17.9 12.3 0.4 4.9 0.5 0.3 5.1 6.2 5.4 13.9 3.1 4.7 3.6 2.9 3.8 6.1 2.5 2.7 CBS HIP4 ENSG00000160200 Cystathionine-beta-synthase P35520 21 43053191-43076943 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" "Allosteric enzyme, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 55.7;pancreas: 43.0" "Cell line enhanced" "Detected in many" "BEWO: 40.2;HAP1: 38.3;HHSteC: 51.8;MCF7: 44.3;RPMI-8226: 42.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 84 "neutrophil: 8.3" "Lineage enriched" "Detected in single" 84 "granulocytes: 8.3" HPA001223 Supported Approved Nucleoli,Vesicles Vesicles Nucleoli "HPA001223: AB_1846112" "unprognostic (4.86e-2)" "unprognostic (1.48e-2)" "unprognostic (6.81e-2)" "unprognostic (1.12e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.68e-4)" "unprognostic (3.62e-1)" "unprognostic (6.76e-3)" "unprognostic (1.06e-1)" "unprognostic (6.50e-2)" "unprognostic (2.13e-1)" "unprognostic (1.61e-2)" "unprognostic (6.73e-3)" "unprognostic (2.62e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-1)" 1.3 1.5 6.5 2.4 5.1 0.4 1.0 12.3 6.7 4.8 1.3 2.0 0.8 1.6 0.9 0.8 0.8 2.0 2.1 2.0 5.6 5.5 1.3 55.7 1.7 1.4 4.8 2.8 13.9 43.0 0.3 1.4 1.4 2.3 4.0 0.7 2.8 9.3 3.4 0.8 0.6 2.9 1.4 3.7 0.8 2.7 2.2 3.3 0.8 5.0 0.8 0.9 2.6 0.8 0.0 0.0 8.3 0.0 0.0 0.0 0.0 6.3 3.8 5.0 19.6 11.3 7.3 40.2 7.8 2.0 3.2 3.3 11.8 0.3 0.0 4.2 14.7 0.4 38.3 2.7 0.6 0.0 4.8 2.6 15.3 14.2 51.8 1.6 3.8 4.4 0.4 3.5 3.1 8.6 29.6 22.3 2.4 44.3 2.7 0.0 4.7 6.7 0.0 0.0 42.4 0.1 3.5 10.4 15.3 17.2 1.0 7.4 6.1 20.0 1.1 0.2 9.9 0.1 0.8 7.8 6.2 8.8 3.6 2.3 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 6.5 5.1 12.3 5.2 5.6 5.5 4.8 2.8 2.3 3.3 CBSL ENSG00000274276 "Cystathionine-beta-synthase like" P0DN79 21 6444869-6468040 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.5;liver: 21.2;pancreas: 18.5" "Cell line enhanced" "Detected in many" "AN3-CA: 35.7;NTERA-2: 66.2;SH-SY5Y: 21.1;U-266/70: 20.9" "Low cancer specificity" "Detected in some" "Cell type enriched" "Detected in single" 47 "neutrophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" HPA001223 Supported Approved Nucleoli,Vesicles 190000 Vesicles Nucleoli "HPA001223: AB_1846112" "unprognostic (2.39e-1)" "unprognostic (1.54e-2)" "unprognostic (1.15e-1)" "unprognostic (4.78e-3)" "unprognostic (6.49e-2)" "unprognostic (1.42e-2)" "unprognostic (1.28e-2)" "unprognostic (6.62e-3)" "unprognostic (1.17e-1)" "unprognostic (3.62e-2)" "unprognostic (7.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (3.17e-3)" "unprognostic (8.44e-2)" "unprognostic (2.46e-1)" "unprognostic (3.61e-1)" 0.0 0.0 0.0 0.0 0.0 11.5 1.8 0.0 0.4 0.0 0.0 0.0 0.3 0.0 1.0 0.0 21.2 0.0 0.0 1.6 18.5 0.0 0.0 1.8 0.0 0.0 3.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 5.0 0.0 0.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 11.9 35.7 0.0 0.0 0.4 7.4 4.3 2.7 8.3 0.1 4.8 0.0 0.0 0.0 3.1 0.0 3.8 1.7 0.0 9.4 0.0 0.0 0.0 0.2 0.0 5.1 4.2 13.9 0.0 7.0 0.0 0.2 16.5 0.1 0.0 5.6 0.6 66.2 0.0 0.0 0.0 0.0 10.8 0.0 13.8 21.1 0.0 1.1 14.4 0.0 0.0 0.0 0.7 0.0 4.6 1.4 20.9 7.7 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853230 "Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 94.9;seminal vesicle: 104.1" "Cell line enhanced" "Detected in some" "Daudi: 49.8;Karpas-707: 13.9;MOLT-4: 12.6;REH: 10.0;U-266/70: 10.8;U-698: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cell: 15.3" "Group enriched" "Detected in all" 4 "B-cells: 9.0;dendritic cells: 5.1;NK-cells: 15.3" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favourable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 4.1 3.3 3.8 17.6 8.5 9.3 2.6 0.7 12.0 1.0 3.2 10.4 14.6 4.3 0.7 0.9 2.3 2.4 1.5 5.0 4.0 4.2 1.2 5.4 4.7 16.1 4.9 3.1 0.6 0.7 0.0 2.5 0.6 3.1 10.8 2.7 4.4 2.8 104.1 14.2 0.5 6.2 0.9 1.8 20.6 2.0 0.7 2.5 94.9 2.8 2.0 13.2 7.6 0.9 9.0 5.1 1.3 2.2 15.3 2.3 3.7 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 49.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 13.9 0.0 0.0 12.6 3.0 0.0 0.0 10.0 0.0 7.8 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 2.2 0.2 0.0 0.0 0.0 0.0 10.8 0.1 9.4 0.1 2.4 0.1 0.0 1.7 0.0 1.1 2.2 0.3 9.0 1.4 1.2 4.1 6.6 2.3 1.8 1.3 15.3 1.4 5.1 2.1 3.7 3.8 8.5 0.7 6.2 4.0 4.2 4.9 3.1 3.1 2.5 CDA CDD ENSG00000158825 "Cytidine deaminase" P32320 1 20588948-20618908 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 126.5;bone marrow: 68.0" "Cell line enhanced" "Detected in many" "A-431: 41.9;CAPAN-2: 28.0;HeLa: 39.7;PC-3: 20.0;SiHa: 49.8;U-937: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 126.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 126.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA064202 Enhanced Approved Nucleoplasm 3700000 Nucleoplasm "HPA064202: " "unprognostic (2.38e-1)" "prognostic unfavourable (5.05e-4)" "unprognostic (2.86e-1)" "unprognostic (2.56e-1)" "unprognostic (8.02e-2)" "unprognostic (3.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.68e-3)" "unprognostic (2.64e-1)" "unprognostic (4.01e-2)" "prognostic unfavourable (8.56e-5)" "unprognostic (2.94e-2)" "unprognostic (5.03e-2)" "unprognostic (8.47e-3)" "unprognostic (2.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.89e-3)" 4.0 1.4 1.5 4.0 1.5 68.0 2.2 1.1 2.4 19.0 8.6 1.7 2.0 2.6 6.7 3.5 38.3 2.9 1.8 5.9 1.7 1.6 12.5 42.1 8.4 9.1 2.0 1.3 2.9 0.8 1.2 0.7 30.8 3.5 4.2 10.2 4.5 6.9 1.5 3.2 7.0 24.7 4.3 1.9 11.8 1.2 2.9 0.9 0.9 3.0 23.3 10.5 3.1 16.5 0.0 1.3 126.5 21.7 0.0 0.1 7.1 41.9 4.1 0.0 0.0 0.0 1.2 0.0 3.2 0.8 0.8 3.3 0.2 28.0 0.0 1.6 6.7 14.7 0.8 11.0 2.2 0.0 0.8 0.0 39.7 5.3 0.3 0.0 0.0 1.8 1.8 7.9 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 20.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 49.8 0.0 0.0 0.0 1.2 0.7 0.0 1.7 3.8 0.2 0.0 0.0 0.0 0.5 17.6 0.0 16.3 21.7 43.3 0.0 11.4 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 126.5 0.0 9.3 0.2 0.0 7.1 1.5 1.5 1.1 2.4 1.7 1.6 2.0 1.3 3.5 0.9 CDC14A "cdc14, Cdc14A1, Cdc14A2, DFNB105" ENSG00000079335 "Cell division cycle 14A" Q9UNH5 1 100345001-100520278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Hearing" "Hydrolase, Protein phosphatase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.2" "Cell line enhanced" "Detected in many" "K-562: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023783 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "HPA023783: AB_1846352" "unprognostic (3.72e-2)" "unprognostic (2.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-2)" "unprognostic (1.54e-3)" "unprognostic (1.38e-1)" "unprognostic (9.27e-4)" "unprognostic (4.88e-3)" "unprognostic (6.30e-2)" "unprognostic (3.97e-3)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-3)" "unprognostic (6.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.49e-2)" "unprognostic (6.66e-2)" 6.2 2.4 5.8 6.5 5.5 13.7 12.2 1.8 6.2 7.7 11.8 4.8 2.2 7.2 15.1 4.8 3.4 13.7 3.6 4.1 8.8 3.5 6.6 2.4 12.3 15.4 3.8 5.4 5.8 6.7 9.8 8.1 7.6 4.6 10.0 6.3 8.3 7.7 3.9 4.3 5.6 22.6 5.0 3.2 9.6 6.0 38.2 4.7 12.0 6.1 3.4 11.3 5.8 8.4 4.8 6.1 11.6 3.7 3.9 13.0 4.1 2.2 1.8 5.8 6.5 2.1 1.6 4.0 2.8 1.9 2.8 2.3 6.1 1.9 1.1 2.1 1.7 1.7 3.9 1.6 2.9 2.2 9.7 3.9 1.7 1.9 0.8 5.2 7.0 1.3 0.4 3.0 1.0 4.9 30.0 3.4 4.1 0.9 4.2 5.9 3.5 2.3 4.6 7.5 1.1 1.9 5.0 1.0 1.8 3.0 2.9 3.9 1.3 6.8 2.1 1.6 3.5 2.6 1.6 1.7 0.6 1.7 1.9 4.9 0.9 11.6 3.7 8.4 7.3 3.3 13.0 4.8 11.3 8.4 3.5 3.1 11.0 5.8 5.5 3.9 2.3 6.1 5.6 4.1 5.8 5.5 1.8 6.2 8.8 3.5 3.8 5.4 4.6 4.7 CDC14B "Cdc14B1, Cdc14B2, CDC14B3, hCDC14B" ENSG00000081377 "Cell division cycle 14B" O60729 9 96490241-96619830 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 15.1;ASC TERT1: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 9.9" "Lineage enhanced" "Detected in many" "granulocytes: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013312, HPA064747" Approved Supported Nucleoplasm Nucleoplasm "HPA013312: AB_1846354, HPA064747: " "unprognostic (5.69e-2)" "unprognostic (9.09e-2)" "unprognostic (3.50e-2)" "unprognostic (8.08e-3)" "unprognostic (4.24e-1)" "unprognostic (1.19e-2)" "unprognostic (1.11e-2)" "unprognostic (4.49e-2)" "unprognostic (1.63e-2)" "unprognostic (2.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.75e-1)" "prognostic favourable (2.97e-10)" "unprognostic (2.01e-2)" "unprognostic (2.61e-1)" "prognostic unfavourable (2.82e-4)" "unprognostic (7.40e-2)" 7.3 6.2 6.8 3.0 7.5 4.4 15.7 2.4 6.6 5.3 5.0 14.8 7.1 4.5 4.0 3.7 3.5 7.1 5.9 8.2 6.0 4.6 9.1 16.0 4.9 1.8 9.5 4.0 5.8 7.3 17.1 5.2 3.4 7.1 5.7 5.4 8.3 3.8 7.2 2.2 3.3 7.7 4.2 9.3 2.2 9.3 16.9 8.2 0.2 13.6 2.2 2.1 10.4 10.3 1.6 0.0 9.9 0.0 0.1 2.9 0.8 5.1 2.9 3.1 3.2 15.1 22.7 8.5 3.8 5.0 2.5 4.1 9.9 8.3 0.0 3.7 8.0 5.8 4.4 3.0 3.0 1.3 4.1 0.8 1.0 7.7 2.4 0.0 0.1 9.3 1.5 2.7 2.5 0.5 3.0 0.6 3.5 2.5 0.0 0.8 5.8 2.5 0.0 1.9 0.1 4.0 8.0 0.9 4.9 2.6 0.8 1.5 0.7 1.7 1.5 2.5 3.0 6.5 2.7 0.1 0.0 0.0 2.7 0.0 6.0 9.9 0.0 3.1 2.9 0.0 1.6 1.6 1.3 2.3 0.0 0.8 2.3 1.4 0.0 0.1 0.0 0.0 1.6 0.8 6.8 7.5 2.4 6.6 6.0 4.6 9.5 4.0 7.1 8.2 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188402 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 23.0;testis: 19.4" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 1.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005855 Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA005855: AB_1846364" "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.8 1.2 1.1 5.5 1.1 13.0 0.8 0.7 1.2 1.1 3.3 0.6 1.0 1.8 0.6 0.9 3.9 0.4 2.2 0.7 1.3 2.4 1.2 0.9 0.7 4.1 1.4 0.2 2.1 3.6 0.4 2.3 4.2 1.2 1.0 4.0 1.5 1.8 0.5 0.7 0.8 2.1 0.8 0.7 3.6 1.3 19.4 0.2 23.0 1.6 8.8 7.4 0.8 1.3 1.7 0.9 0.5 0.1 0.0 1.0 0.1 7.5 3.7 17.8 9.6 0.6 1.2 12.3 10.5 4.0 13.2 10.7 16.1 3.9 22.4 4.1 2.7 5.7 30.5 7.2 13.9 7.3 16.0 28.7 6.8 7.9 0.6 20.2 8.3 0.6 1.1 16.4 7.1 5.0 22.8 11.9 7.1 4.0 25.2 15.7 26.0 8.5 11.3 11.7 12.2 3.3 7.1 8.4 10.4 6.5 7.6 3.3 4.0 14.3 2.5 6.5 10.0 7.2 14.2 6.0 17.9 35.2 4.8 22.5 5.4 0.0 0.0 0.5 0.4 0.0 0.0 1.7 0.6 0.2 0.9 0.0 0.0 1.0 0.0 0.0 0.1 0.5 0.0 0.1 1.1 1.1 0.7 1.2 1.3 2.4 1.4 0.2 1.2 0.2 CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 4.5;NK-cells: 9.3;T-cells: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Supported "Vesicles,Mitotic spindle" Vesicles "Mitotic spindle" "HPA038892: , HPA038893: , HPA075215: " "unprognostic (4.69e-2)" "unprognostic (5.74e-2)" "unprognostic (2.93e-2)" "prognostic unfavourable (4.76e-4)" "unprognostic (1.13e-1)" "unprognostic (4.23e-1)" "prognostic unfavourable (1.19e-4)" "unprognostic (1.31e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "prognostic unfavourable (2.94e-13)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (3.94e-1)" "unprognostic (9.46e-2)" 12.1 8.7 15.1 27.7 23.3 26.0 28.8 49.6 21.1 13.0 14.7 12.8 4.6 14.9 17.0 10.3 11.7 13.0 18.6 7.5 15.7 12.5 13.3 11.0 33.0 42.8 21.9 12.5 17.3 5.7 7.5 21.0 30.3 13.8 11.0 12.0 7.7 7.4 10.2 6.2 19.8 16.8 14.8 14.7 24.5 14.1 6.3 22.3 33.3 18.7 20.8 31.6 15.3 16.3 4.5 1.3 1.5 1.8 9.3 15.5 5.9 29.8 64.5 8.6 14.3 10.6 10.4 4.3 14.8 22.2 24.8 18.5 11.2 43.3 20.8 6.4 15.1 43.7 11.7 24.6 11.7 8.0 12.6 11.2 20.7 13.5 42.3 8.7 5.8 10.2 19.8 23.0 27.2 13.7 7.2 55.1 14.6 24.0 27.1 12.7 6.4 27.6 14.2 24.4 14.9 16.9 2.8 6.2 13.5 35.1 33.5 17.2 11.3 4.5 11.3 13.3 16.1 24.1 19.6 13.4 21.2 8.4 6.8 8.6 12.8 1.5 1.4 0.0 13.6 1.8 12.7 3.5 13.6 13.7 1.3 4.5 11.4 13.2 0.1 9.3 0.9 0.7 15.5 5.9 15.1 23.3 49.6 21.1 15.7 12.5 21.9 12.5 13.8 22.3 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285265-138338355 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 23.3;testis: 22.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.1;T-reg: 2.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB003800, HPA066991" Approved Supported "Nuclear speckles" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: " "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favourable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavourable (3.03e-6)" "prognostic unfavourable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 1.1 0.6 0.3 6.7 0.4 5.2 1.1 0.4 0.6 0.6 3.3 0.1 0.7 3.0 0.3 0.6 2.5 0.2 0.4 0.7 0.4 0.4 0.4 0.6 0.7 2.6 0.4 0.3 0.3 0.3 0.0 0.4 1.9 0.3 0.4 4.0 0.0 1.2 0.7 0.2 1.1 3.7 0.5 0.3 1.7 1.2 22.3 0.2 23.3 0.3 1.8 5.0 0.6 0.9 1.0 0.1 0.7 0.0 2.1 2.7 0.5 13.5 5.6 19.0 14.6 0.4 1.9 4.8 8.1 8.8 18.6 25.7 13.6 26.3 6.3 6.9 4.9 7.3 15.6 12.5 18.0 5.2 10.7 4.8 7.7 10.1 0.1 3.2 4.9 0.4 0.5 11.0 9.0 11.9 7.0 12.4 11.3 7.4 8.8 8.1 4.9 6.2 5.8 17.3 7.3 3.2 4.1 9.6 5.9 18.3 5.6 8.7 9.3 6.7 3.6 10.3 8.7 7.1 13.0 7.6 6.2 6.2 4.1 6.9 7.8 0.0 0.0 0.1 0.6 0.0 0.0 1.0 0.5 0.3 0.0 0.2 0.0 0.0 0.7 2.1 0.0 0.1 2.7 0.5 0.3 0.4 0.4 0.6 0.4 0.4 0.4 0.3 0.3 0.2 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34" P49427 19 531712-542092 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311" Approved Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370" "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavourable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 16.5 15.9 21.3 11.3 19.1 24.7 20.4 25.7 30.9 16.0 20.5 19.5 10.5 15.4 13.3 13.4 15.6 14.5 13.6 35.6 21.1 18.2 12.1 36.0 13.0 9.9 18.5 19.8 17.0 37.4 11.3 17.0 24.9 16.2 17.2 10.6 15.3 26.4 18.5 63.9 19.0 13.2 18.6 14.3 12.7 15.7 43.6 15.0 12.2 13.1 17.0 8.7 19.2 16.4 2.9 2.8 11.5 4.5 1.5 4.1 1.3 18.4 18.4 23.7 19.5 10.8 10.3 23.7 16.6 12.7 17.9 18.7 28.6 11.3 10.2 17.4 11.8 12.8 18.6 14.0 9.2 16.6 50.0 9.4 12.2 30.9 26.9 13.2 11.4 13.3 21.0 15.1 15.8 21.3 40.2 20.4 11.8 26.4 18.0 17.6 29.9 17.9 16.7 12.2 17.1 13.5 11.0 30.9 22.9 14.4 15.0 27.6 12.0 19.4 17.4 13.1 15.6 30.4 22.1 20.4 15.6 13.6 17.9 18.7 13.5 4.5 3.5 6.2 2.3 3.4 1.7 2.9 3.2 4.1 2.8 1.7 2.5 2.4 11.5 1.5 4.5 2.3 3.1 1.3 21.3 19.1 25.7 30.9 21.1 18.2 18.5 19.8 16.2 15.0 CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Intermediate filaments" "Intermediate filaments" "CAB070414: AB_11156796, HPA071252: " "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" 17.2 15.2 19.1 8.6 21.1 3.9 14.0 29.2 20.4 21.1 19.3 16.4 13.1 16.9 15.8 9.9 12.3 12.9 16.6 14.1 21.7 17.7 20.8 17.0 11.7 3.5 20.0 16.3 17.4 15.1 29.3 29.6 14.8 19.3 21.1 12.4 11.0 8.4 18.5 11.9 7.6 17.2 27.6 16.6 8.8 25.2 26.7 19.9 0.7 9.8 7.3 2.5 23.4 23.1 0.1 0.7 2.0 0.1 0.0 0.1 0.0 9.3 8.9 9.5 4.4 9.5 11.8 3.3 10.7 15.2 7.4 7.8 7.2 21.3 0.0 11.6 17.8 4.3 6.9 6.0 9.1 0.0 5.6 7.2 10.5 2.8 10.8 5.8 3.2 8.2 7.7 12.0 12.1 24.8 18.4 0.0 12.1 2.5 0.1 1.0 7.7 8.5 0.0 16.0 0.0 12.0 18.1 6.8 10.0 18.2 7.6 10.7 9.9 0.3 24.9 13.7 7.1 15.5 14.2 0.0 0.0 0.0 18.1 0.0 18.2 2.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 19.1 21.1 29.2 20.4 21.7 17.7 20.0 16.3 19.3 19.9 CDC42BPB "KIAA1124, MRCKB" ENSG00000198752 "CDC42 binding protein kinase beta" Q9Y5S2 14 102932379-103057462 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022821 Approved 12000 "HPA022821: AB_1846376" "unprognostic (6.73e-2)" "unprognostic (2.19e-2)" "unprognostic (6.99e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (2.90e-2)" "prognostic unfavourable (2.38e-4)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "unprognostic (3.46e-2)" "unprognostic (2.28e-1)" "prognostic favourable (8.67e-10)" "unprognostic (2.11e-1)" "unprognostic (1.86e-1)" "unprognostic (8.59e-2)" "unprognostic (7.56e-2)" 32.2 22.7 33.1 14.8 33.2 3.1 19.8 30.3 42.1 26.7 21.8 42.3 21.5 26.0 27.0 18.7 28.3 26.0 28.1 30.7 31.4 25.5 23.7 20.1 26.4 7.9 31.2 28.4 29.7 28.8 32.5 25.9 25.6 27.0 25.1 18.2 23.7 23.0 28.8 17.0 23.8 29.6 28.7 24.3 18.3 25.5 21.8 31.0 2.1 26.3 15.9 12.4 25.2 32.6 0.9 0.2 0.0 2.0 0.0 0.4 0.1 13.1 26.4 17.0 12.4 18.9 21.7 17.1 15.1 16.0 16.0 14.8 9.0 15.5 0.0 16.6 29.4 16.8 17.5 18.0 17.1 16.0 7.9 7.2 21.3 9.0 20.6 0.0 7.8 18.7 18.7 16.4 15.8 31.1 5.8 3.7 15.4 27.6 0.1 1.6 8.1 21.8 0.0 14.3 0.3 20.5 25.9 12.4 13.5 26.8 10.1 11.3 15.6 4.6 39.5 15.4 10.4 34.0 14.0 4.9 5.2 3.8 17.3 1.6 14.9 0.0 1.4 0.0 0.0 2.0 0.0 0.9 0.4 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 33.1 33.2 30.3 42.1 31.4 25.5 31.2 28.4 27.0 31.0 CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823387-64844569 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 19.1;HaCaT: 14.3;MCF7: 19.3;RT4: 11.7;SK-BR-3: 11.9;T-47d: 11.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 9 "cerebellum: 19.4" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.0" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in single" 4 "cerebellum: 5.9" "Low region specificity" "Detected in single" "HPA027382, HPA061836" Enhanced Supported Cytosol Cytosol "HPA027382: AB_1846378, HPA061836: " "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favourable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" 0.5 2.7 0.8 2.1 0.5 1.1 3.5 19.4 0.8 2.9 9.1 0.8 6.3 8.2 1.0 8.0 14.3 2.9 10.5 0.5 0.7 0.0 3.5 0.5 4.2 0.7 0.5 0.5 1.5 7.9 7.0 6.5 13.0 2.0 4.4 3.4 1.0 14.3 7.6 0.5 22.4 19.7 1.6 0.8 0.8 8.5 2.5 0.7 1.8 3.9 8.1 7.7 5.4 6.3 0.4 0.0 0.0 0.0 0.2 1.0 0.1 5.5 0.8 0.5 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 7.4 4.7 0.1 2.8 0.0 14.3 0.8 5.6 0.0 0.2 2.2 0.4 3.1 2.3 0.0 0.1 1.4 0.0 7.0 0.0 0.1 0.0 3.7 0.0 0.0 19.3 0.1 1.0 1.7 0.8 0.8 0.3 2.6 3.4 11.7 10.2 0.5 1.8 11.9 0.3 11.6 0.2 0.0 0.0 2.0 0.0 0.0 1.3 1.3 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.8 0.5 19.4 0.8 0.7 0.0 0.5 0.5 2.0 0.7 CDC7 "CDC7L1, HsCdc7, Hsk1, huCdc7" ENSG00000097046 "Cell division cycle 7" O00311 1 91500893-91525764 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002669, HPA035831" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "CAB002669: , HPA035831: " "unprognostic (6.84e-2)" "unprognostic (6.01e-2)" "unprognostic (4.64e-2)" "unprognostic (7.02e-3)" "unprognostic (5.57e-2)" "unprognostic (3.57e-3)" "prognostic unfavourable (3.15e-6)" "unprognostic (6.52e-2)" "unprognostic (2.23e-2)" "unprognostic (1.36e-3)" "unprognostic (2.04e-2)" "unprognostic (1.75e-2)" "prognostic unfavourable (1.89e-15)" "unprognostic (9.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.09e-1)" "unprognostic (5.39e-2)" 2.5 3.7 5.7 7.6 8.9 15.4 4.3 19.4 10.3 2.5 4.2 1.4 0.9 4.2 2.8 2.6 4.7 1.7 2.6 1.9 6.8 5.2 3.6 2.3 5.1 11.7 4.0 4.7 3.7 2.4 2.2 12.3 7.9 5.2 2.7 6.8 2.3 2.5 2.3 1.0 6.8 4.9 3.3 5.9 15.1 2.6 21.2 4.7 18.7 2.5 4.5 12.0 4.2 3.0 1.6 3.5 0.1 1.6 2.4 6.5 2.1 14.0 4.2 27.1 7.7 0.6 3.6 8.6 5.3 4.2 10.5 11.5 8.7 5.0 9.7 7.5 3.3 6.1 17.8 6.0 14.6 16.1 15.3 14.8 12.0 4.1 1.0 16.1 5.4 1.9 1.8 9.6 5.5 4.0 19.5 14.2 7.2 5.1 13.7 14.4 22.5 9.9 17.1 22.5 6.2 4.6 10.6 21.6 8.5 16.9 4.7 9.4 4.4 7.9 3.3 12.0 10.6 9.2 8.0 5.2 6.6 26.1 4.3 15.6 4.4 0.0 1.6 0.0 5.9 1.2 5.2 1.5 4.5 5.6 3.5 1.6 2.5 5.1 0.1 2.4 0.3 2.1 6.5 2.1 5.7 8.9 19.4 10.3 6.8 5.2 4.0 4.7 5.2 4.7 CDIPT "PIS, PIS1" ENSG00000103502 "CDP-diacylglycerol--inositol 3-phosphatidyltransferase" O14735 16 29858357-29863736 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056597 Approved Approved "Nucleoplasm,Nuclear membrane,Plasma membrane" "Nucleoplasm, Nuclear membrane, Plasma membrane" "HPA056597: " "unprognostic (7.81e-2)" "prognostic favourable (9.40e-4)" "unprognostic (1.93e-3)" "unprognostic (8.08e-3)" "unprognostic (1.50e-2)" "unprognostic (2.84e-2)" "unprognostic (7.60e-2)" "unprognostic (1.09e-2)" "unprognostic (7.03e-2)" "unprognostic (8.75e-2)" "unprognostic (5.56e-3)" "unprognostic (1.61e-1)" "unprognostic (6.17e-2)" "unprognostic (3.36e-2)" "unprognostic (6.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.48e-1)" 40.4 40.8 24.3 20.2 28.1 15.3 42.9 50.7 39.5 37.1 37.2 21.5 33.9 24.8 33.4 23.0 39.4 30.1 34.5 44.4 23.1 27.9 34.8 66.3 27.1 22.4 24.1 26.4 52.7 40.0 47.1 24.9 43.7 21.8 36.8 16.1 29.3 42.2 38.8 21.0 29.6 32.6 31.8 21.0 25.6 29.5 20.2 16.4 30.4 47.1 19.9 17.3 41.8 42.8 4.8 6.1 20.6 6.5 8.2 8.4 2.7 12.3 26.8 7.5 15.1 41.3 28.6 22.4 21.7 24.3 15.4 15.4 15.6 23.8 8.3 41.1 25.0 19.5 12.2 14.0 7.1 20.7 24.5 5.9 20.0 22.8 28.8 8.8 15.4 48.3 24.8 20.7 9.5 19.3 8.8 21.5 13.9 39.4 11.9 17.4 18.0 20.0 23.3 9.4 24.1 20.3 11.9 31.2 17.5 11.5 24.5 17.1 18.3 23.9 16.7 22.9 7.2 18.6 11.1 16.0 18.1 5.9 25.0 14.2 13.8 7.5 6.5 20.6 6.9 4.6 4.6 4.7 6.4 7.3 3.0 4.8 6.3 5.9 16.4 8.2 5.7 6.1 8.4 2.7 24.3 28.1 50.7 39.5 23.1 27.9 24.1 26.4 21.8 16.4 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 88.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cell: 6.1;T-reg: 5.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;NK-cells: 6.1;T-cells: 5.7" "Low region specificity" "Detected in single" "HPA003387, CAB003799" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB003799: AB_344898, HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favourable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavourable (1.10e-6)" "prognostic unfavourable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavourable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 4.1 2.2 0.8 17.8 2.4 17.8 4.4 0.7 1.6 4.2 6.5 1.1 3.4 6.1 2.9 4.8 19.0 1.5 2.4 2.3 0.9 0.7 3.1 1.7 5.7 15.1 1.7 0.6 2.2 1.0 0.5 4.4 13.3 1.2 1.5 8.3 1.0 3.8 2.9 1.0 4.9 8.3 2.7 2.5 8.3 5.0 13.8 1.2 88.4 1.8 16.7 20.1 3.2 6.9 0.9 1.7 0.0 0.2 6.1 5.7 1.8 48.2 18.4 48.9 19.3 3.2 4.9 20.1 36.5 26.6 44.5 42.9 43.0 42.7 44.2 14.2 10.0 30.0 33.2 21.2 46.4 31.4 24.2 23.2 18.1 24.9 0.5 35.5 24.0 0.9 2.1 28.8 28.1 26.7 35.3 54.5 49.5 12.8 44.6 25.5 21.5 38.7 38.8 45.5 21.7 17.0 16.0 22.9 20.1 24.5 37.3 18.9 40.2 21.8 11.0 19.0 40.6 20.0 49.8 21.4 34.3 39.9 16.4 39.8 23.6 0.0 0.0 0.0 0.5 0.2 0.5 0.9 1.5 2.7 0.5 0.5 0.5 1.5 0.0 6.1 0.2 1.7 5.7 1.8 0.8 2.4 0.7 1.6 0.9 0.7 1.7 0.6 1.2 1.2 CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696364 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007451, HPA059634, HPA067060" Uncertain Supported "Nucleoplasm,Midbody,Midbody ring" Nucleoplasm "Midbody, Midbody ring" "HPA007451: , HPA059634: , HPA067060: " "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (3.74e-3)" "unprognostic (9.87e-2)" "unprognostic (1.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.53e-1)" "unprognostic (9.06e-2)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "prognostic favourable (2.69e-4)" "unprognostic (2.58e-2)" "unprognostic (2.93e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (6.88e-2)" "prognostic favourable (3.63e-4)" 12.3 19.9 16.8 16.4 23.8 17.3 10.1 14.8 21.9 11.1 18.3 8.1 16.4 23.4 12.1 21.7 14.4 14.4 19.4 8.7 15.3 12.6 22.2 33.9 11.8 14.0 13.3 19.4 11.3 22.2 21.6 27.7 13.6 15.8 13.6 12.6 8.1 17.2 8.9 17.5 14.1 20.7 9.0 10.7 15.9 19.0 8.7 13.6 8.0 27.1 10.1 12.1 10.8 14.5 7.8 14.5 3.4 15.3 15.2 13.3 8.8 14.5 9.5 7.7 3.1 3.2 6.1 8.0 12.0 6.8 8.6 2.9 7.3 11.1 12.9 6.2 10.4 10.2 3.3 16.8 5.4 2.8 8.0 5.1 10.6 0.8 13.2 8.2 9.3 7.4 5.6 5.4 8.2 15.0 13.3 1.7 9.8 19.0 9.9 23.5 15.6 7.2 14.4 10.4 18.1 15.4 11.6 7.5 16.3 15.1 7.0 3.5 16.5 13.0 13.2 5.9 15.1 6.1 8.2 6.6 3.6 4.0 8.9 14.2 8.3 3.2 11.7 3.4 12.9 15.3 10.9 6.8 11.4 8.9 14.5 7.8 13.3 10.9 1.5 15.2 11.2 10.0 8.8 8.8 16.8 23.8 14.8 21.9 15.3 12.6 13.3 19.4 15.8 13.6 CDK11A "CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE" ENSG00000008128 "Cyclin dependent kinase 11A" Q9UQ88 1 1702730-1724324 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.5" "Low lineage specificity" "Detected in all" "CAB010467, HPA025061, HPA073626" Supported Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB010467: AB_631212, HPA025061: AB_1846407, HPA073626: " "unprognostic (6.25e-2)" "unprognostic (8.32e-2)" "unprognostic (1.47e-2)" "unprognostic (2.74e-1)" "unprognostic (9.32e-3)" "unprognostic (3.54e-2)" "unprognostic (2.25e-3)" "unprognostic (7.97e-2)" "prognostic unfavourable (5.06e-4)" "unprognostic (1.28e-1)" "unprognostic (5.58e-3)" "unprognostic (3.07e-2)" "prognostic unfavourable (1.15e-6)" "unprognostic (1.97e-1)" "unprognostic (5.98e-2)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" 14.3 14.9 17.2 23.7 26.9 39.7 13.0 35.2 32.7 12.5 16.4 14.3 6.1 29.2 16.5 8.5 12.1 12.6 10.2 10.2 19.4 8.4 11.7 12.5 19.0 20.3 22.6 9.0 16.2 12.9 12.2 27.5 12.9 17.1 14.4 14.6 11.6 12.7 10.3 21.5 15.1 34.9 13.1 26.0 24.2 15.7 16.4 25.1 14.9 14.6 7.6 22.4 13.5 15.2 7.4 11.8 33.5 6.3 4.4 5.5 1.4 16.1 9.7 7.0 6.4 9.2 7.4 6.9 15.9 7.1 7.9 9.2 12.2 14.8 17.2 9.7 4.6 12.0 6.5 8.2 6.3 13.1 10.4 15.3 18.3 10.9 6.1 17.1 22.1 8.5 5.6 6.9 4.5 13.6 17.9 14.4 6.6 9.1 7.9 13.4 9.7 8.3 14.5 10.7 8.3 6.4 7.3 7.8 11.3 13.9 16.4 19.1 11.0 7.1 13.8 12.5 12.1 5.6 8.8 20.1 14.6 21.6 4.2 13.9 3.9 16.7 6.3 7.7 5.5 3.4 4.2 6.2 4.7 4.2 2.0 7.4 4.7 4.0 33.5 4.4 3.7 11.8 4.5 1.4 17.2 26.9 35.2 32.7 19.4 8.4 22.6 9.0 17.1 25.1 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461511-39564907 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 16.0 13.1 12.4 17.4 9.2 32.4 14.0 23.4 17.8 18.2 17.6 9.6 15.7 11.1 15.7 12.0 16.9 12.2 12.5 11.0 10.1 6.7 10.2 18.5 13.5 15.2 10.9 14.3 17.4 11.3 19.0 12.2 18.4 9.5 12.7 11.7 10.4 15.6 11.1 11.1 17.0 16.5 11.0 10.6 16.3 11.8 18.9 8.3 29.0 15.0 5.4 17.3 16.3 20.5 5.1 4.0 10.4 2.9 6.6 4.0 0.9 8.7 10.8 6.5 6.1 4.8 5.4 6.1 7.9 6.7 10.9 8.1 13.3 5.4 12.4 7.0 8.3 14.2 13.0 10.0 10.5 8.1 11.2 13.4 7.4 10.3 4.7 18.3 9.4 5.8 6.9 13.2 10.5 6.6 22.7 8.2 6.2 4.1 14.9 4.7 6.8 4.9 9.9 14.1 7.0 4.1 10.5 7.0 4.5 10.1 85.6 6.9 11.0 7.9 7.1 9.9 7.9 6.9 10.2 6.7 4.8 17.5 7.0 7.8 6.4 10.4 2.9 4.1 4.0 2.2 3.0 2.9 2.5 2.7 1.8 5.1 2.9 2.7 9.7 6.6 1.8 4.0 2.0 0.9 12.4 9.2 23.4 17.8 10.1 6.7 10.9 14.3 9.5 8.3 CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39949646-40099580 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles" "Nuclear speckles" "HPA059241: " "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (4.18e-3)" "unprognostic (3.42e-2)" "unprognostic (8.09e-2)" "unprognostic (1.13e-2)" "unprognostic (3.77e-2)" "unprognostic (8.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.33e-2)" "unprognostic (3.53e-1)" "unprognostic (3.53e-2)" 16.9 15.3 16.0 29.0 14.5 26.7 20.4 23.3 18.2 16.6 18.3 16.4 14.2 11.3 20.3 17.7 20.9 18.1 20.2 13.6 14.3 11.3 14.7 17.5 19.6 21.9 16.5 15.1 24.2 15.3 26.3 15.3 14.8 12.0 15.5 15.5 14.9 17.6 14.5 19.4 16.7 16.3 16.4 11.5 17.4 14.5 20.2 15.7 31.2 23.1 14.6 21.5 18.5 23.6 14.0 3.9 7.9 3.4 5.0 5.0 1.4 15.6 9.3 16.3 15.5 14.7 14.4 11.2 12.5 13.6 11.5 14.4 9.7 10.8 28.4 7.3 13.1 19.1 13.3 11.0 17.0 13.9 9.8 12.6 11.4 8.8 14.1 19.2 13.8 8.5 14.8 13.1 17.6 13.5 21.3 19.7 11.9 8.0 15.2 13.6 23.5 10.9 16.9 10.8 11.4 10.8 15.8 11.6 16.8 15.9 34.4 11.3 14.1 23.9 16.0 15.9 15.2 10.2 17.0 16.2 13.7 23.4 11.6 17.4 20.2 7.9 2.7 4.4 5.0 2.2 3.4 7.6 4.8 3.7 1.5 14.0 4.9 4.9 7.6 5.0 3.4 3.9 4.3 1.4 16.0 14.5 23.3 18.2 14.3 11.3 16.5 15.1 12.0 15.7 CDK14 "PFTAIRE1, PFTK1" ENSG00000058091 "Cyclin dependent kinase 14" O94921 7 90466424-91210590 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 30.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 7.5;memory B-cell: 9.8;naive B-cell: 5.3;neutrophil: 5.6" "Group enriched" "Detected in many" 9 "B-cells: 9.8;granulocytes: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015267 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA015267: AB_1855249" "prognostic favourable (5.86e-4)" "unprognostic (3.96e-1)" "unprognostic (1.91e-2)" "unprognostic (2.09e-3)" "unprognostic (1.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.72e-1)" "unprognostic (4.48e-2)" "unprognostic (3.60e-2)" "unprognostic (3.09e-2)" "unprognostic (2.77e-3)" "unprognostic (2.91e-2)" "unprognostic (2.57e-2)" "prognostic unfavourable (7.79e-4)" "unprognostic (2.46e-1)" "unprognostic (2.86e-1)" "unprognostic (4.39e-3)" 8.2 4.7 19.8 7.1 19.4 6.1 8.3 28.6 34.9 10.6 5.2 3.7 0.6 2.7 8.6 3.2 3.1 12.0 11.9 11.5 25.8 15.5 19.8 12.7 9.2 10.9 17.3 17.4 14.9 14.2 3.8 14.2 5.9 22.8 11.3 3.4 4.3 7.7 7.0 5.4 2.7 3.8 7.4 7.0 7.5 7.4 7.2 4.5 0.9 13.1 1.6 11.9 6.9 6.7 9.8 0.9 7.5 0.7 0.1 0.2 0.6 7.0 0.0 14.1 1.8 13.2 13.4 3.2 5.9 5.6 3.6 3.9 0.1 3.4 25.0 0.7 5.8 2.1 0.7 8.3 7.0 0.0 3.3 0.0 4.7 0.1 6.1 7.1 0.1 9.5 2.1 10.8 3.9 4.6 0.1 30.8 7.3 0.0 0.0 2.7 8.9 3.8 19.2 19.4 19.0 1.9 1.9 3.1 9.1 15.0 0.0 0.3 1.9 3.6 11.3 15.7 20.1 13.1 9.0 17.4 13.3 17.9 5.9 9.4 15.3 7.5 0.3 0.5 0.0 0.7 0.0 9.8 0.0 0.0 0.9 5.3 0.0 0.0 5.6 0.1 0.5 0.1 0.2 0.6 19.8 19.4 28.6 34.9 25.8 15.5 17.3 17.4 22.8 4.5 CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.2;ovary: 9.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 14.6;BJ hTERT+ SV40 Large T+ RasG12V: 11.9;HBF TERT88: 18.2;HMC-1: 34.4;LHCN-M2: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 52 "basophil: 3.5;eosinophil: 6.9" "Lineage enriched" "Detected in single" 69 "granulocytes: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA015786: AB_1844780" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.80e-2)" "unprognostic (7.38e-2)" "unprognostic (9.99e-5)" "unprognostic (6.31e-2)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" 1.3 0.2 0.1 5.2 0.1 0.0 3.7 0.3 0.1 3.4 2.3 0.1 0.1 0.3 4.1 20.2 1.1 1.0 4.2 0.3 0.1 0.0 0.4 0.1 3.3 0.1 0.1 0.1 9.8 0.2 0.0 0.5 0.1 0.1 2.0 0.7 1.4 0.6 0.3 0.7 1.1 3.0 3.9 0.1 0.1 1.1 2.5 0.1 0.1 0.2 1.2 1.2 1.6 1.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.7 0.0 3.1 14.6 5.5 11.9 0.0 1.5 0.0 0.0 1.3 0.0 0.0 0.0 18.2 0.0 0.0 1.0 0.0 0.0 0.2 0.0 34.4 2.0 0.0 1.5 0.7 0.0 0.0 0.0 10.2 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Uncertain "Plasma membrane,Microtubules,Cytosol" "Plasma membrane, Microtubules, Cytosol" "CAB016535: AB_785112, HPA000974: , HPA001366: AB_1079584" "unprognostic (2.37e-3)" "unprognostic (6.93e-2)" "unprognostic (2.96e-2)" "unprognostic (1.16e-3)" "unprognostic (8.80e-2)" "unprognostic (2.92e-2)" "prognostic unfavourable (2.02e-6)" "unprognostic (2.85e-1)" "unprognostic (5.59e-2)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" 22.0 20.1 32.3 13.9 25.0 26.6 17.6 51.5 49.0 17.2 19.3 15.5 17.0 16.4 14.8 12.8 23.8 18.8 14.1 47.3 29.2 18.0 19.9 12.7 14.0 10.8 22.0 21.1 16.7 18.6 22.8 14.9 18.6 28.5 12.7 14.7 13.7 20.1 16.1 91.2 17.0 15.3 18.2 14.8 12.0 14.7 28.7 12.1 10.4 20.9 36.3 12.6 12.9 12.1 8.5 13.5 8.5 10.7 6.3 7.7 5.7 41.2 31.7 30.4 44.9 22.3 19.2 30.4 19.6 24.2 29.9 22.3 35.6 20.0 9.9 12.5 35.2 23.4 32.3 41.8 20.2 11.9 51.3 10.8 44.5 27.7 29.0 11.3 25.2 23.9 26.8 42.4 51.2 26.7 16.0 16.9 26.1 35.9 9.8 26.0 23.8 34.2 10.5 24.1 17.4 22.5 32.7 25.7 19.4 53.3 41.3 20.2 36.8 13.9 26.8 20.0 32.8 30.5 23.4 13.3 13.0 9.7 17.6 52.7 22.4 3.1 8.8 8.5 4.8 10.7 6.2 3.8 6.2 7.7 11.6 8.5 5.6 5.8 4.2 6.3 9.6 13.5 6.0 5.7 32.3 25.0 51.5 49.0 29.2 18.0 22.0 21.1 28.5 12.1 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400560 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 43.7;TIME: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavourable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 16.3 9.1 20.6 13.9 47.0 31.5 14.7 17.8 35.7 11.8 12.9 23.6 3.4 9.2 20.7 7.5 11.7 10.9 12.9 9.4 25.3 17.3 9.2 12.4 15.9 15.2 23.8 21.0 12.9 8.0 9.9 7.3 24.3 14.8 11.4 9.8 5.7 7.5 9.3 7.3 9.1 9.3 23.4 19.6 15.8 7.9 19.9 28.0 29.6 9.4 6.1 16.6 11.0 10.7 9.6 5.3 29.1 4.7 16.5 14.8 8.6 4.8 4.1 10.8 2.9 5.3 14.0 7.7 10.9 15.4 9.6 9.1 2.4 2.8 7.2 7.6 7.9 4.4 6.4 6.7 13.2 7.6 4.9 10.4 2.8 3.4 11.5 5.5 6.0 10.2 7.0 14.2 25.7 43.7 7.6 5.9 21.7 3.0 5.2 8.7 4.7 7.2 9.1 5.8 6.2 11.4 4.1 5.6 3.8 6.4 6.0 7.9 4.6 5.0 52.4 8.6 3.3 4.6 5.9 8.3 6.3 7.8 3.2 2.4 6.3 29.1 3.4 8.9 12.7 4.7 13.7 9.6 10.4 14.4 5.3 8.8 14.8 12.6 12.8 16.5 4.6 3.9 8.1 8.6 20.6 47.0 17.8 24.6 25.3 17.3 23.8 21.0 14.8 28.0 CDK18 "PCTAIRE3, PCTK3" ENSG00000117266 "Cyclin dependent kinase 18" Q07002 1 205504595-205532793 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.7;heart muscle: 58.9" "Cell line enhanced" "Detected in many" "HBEC3-KT: 20.9;HeLa: 18.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045429 Approved Approved "Actin filaments" "Actin filaments" "HPA045429: AB_10961257" "unprognostic (7.95e-2)" "unprognostic (3.42e-1)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (7.06e-3)" "unprognostic (2.93e-1)" "unprognostic (2.95e-1)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (2.81e-1)" "prognostic unfavourable (5.07e-6)" "unprognostic (6.07e-2)" "unprognostic (1.45e-1)" "unprognostic (6.12e-2)" "prognostic favourable (2.81e-5)" 2.6 4.3 13.6 2.7 31.8 1.0 2.4 4.2 25.0 7.6 6.9 38.1 20.2 17.3 3.4 4.0 2.7 5.7 6.4 58.9 22.1 16.2 13.7 4.7 6.5 1.9 47.8 16.7 7.5 10.7 3.7 4.0 9.6 22.1 3.1 6.1 5.3 16.5 23.5 3.9 1.6 15.1 4.8 98.7 3.5 9.1 0.9 36.4 0.4 4.8 1.4 2.5 3.7 4.7 0.1 1.4 0.0 2.1 0.6 0.9 0.6 12.2 0.8 0.1 0.6 0.0 0.0 13.2 0.2 2.5 0.6 3.2 5.5 9.2 7.3 1.8 0.1 11.0 2.7 20.9 0.5 2.0 2.4 1.7 18.4 5.6 2.3 0.0 0.0 1.4 1.1 0.0 0.4 0.0 0.1 8.8 0.1 9.9 0.7 0.3 10.4 0.4 0.9 0.0 9.1 2.0 7.8 4.3 1.7 3.7 1.8 8.1 8.2 3.5 0.0 0.0 5.0 0.1 0.0 2.5 1.2 1.5 0.1 5.2 2.1 0.0 0.8 0.0 0.1 2.1 0.9 0.0 0.2 0.0 1.4 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.6 13.6 31.8 4.2 19.7 22.1 16.2 47.8 16.7 22.1 36.4 CDK19 "bA346C16.3, CDC2L6, CDK11, KIAA1028" ENSG00000155111 "Cyclin dependent kinase 19" Q9BWU1 6 110609978-110815958 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 8.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007053 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA007053: AB_1846369" "unprognostic (1.66e-2)" "unprognostic (1.84e-1)" "unprognostic (3.63e-1)" "unprognostic (3.00e-3)" "unprognostic (1.62e-1)" "unprognostic (2.66e-3)" "prognostic unfavourable (3.56e-4)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" "unprognostic (2.00e-3)" "unprognostic (3.94e-1)" "unprognostic (4.04e-1)" "prognostic unfavourable (4.72e-5)" "unprognostic (1.75e-1)" "unprognostic (9.78e-2)" "unprognostic (6.51e-2)" "unprognostic (9.50e-3)" 5.3 3.3 18.1 6.1 29.4 9.7 6.0 13.8 21.3 6.6 6.3 31.1 2.4 4.8 9.6 3.7 7.8 5.3 7.8 4.1 20.8 10.1 6.3 4.6 6.2 8.0 22.1 12.9 9.7 3.1 8.0 4.1 10.5 14.4 25.8 6.1 3.4 4.5 5.9 3.2 7.9 5.9 7.1 20.8 7.0 6.5 16.4 26.3 6.1 5.8 1.3 8.4 5.9 6.4 1.3 1.8 8.5 2.2 1.3 0.8 0.6 3.6 3.8 13.4 16.2 7.3 10.5 7.0 11.6 12.4 4.4 5.8 4.8 4.0 9.1 4.2 8.2 2.1 5.1 2.5 10.1 11.3 3.0 15.6 5.7 5.6 4.4 6.3 11.7 7.2 5.5 6.0 9.3 4.3 4.7 12.8 9.4 5.8 8.4 9.4 1.3 2.6 9.1 6.9 3.5 5.1 6.6 6.9 12.8 8.9 7.2 10.4 2.4 23.2 4.8 9.2 4.9 18.6 7.1 1.4 1.8 7.9 9.7 8.5 9.5 3.3 2.2 1.5 0.8 1.2 0.8 1.1 0.7 0.7 1.8 1.3 0.5 0.7 8.5 1.3 0.7 0.9 0.8 0.6 18.1 29.4 13.8 21.3 20.8 10.1 22.1 12.9 14.4 26.3 CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966769-55972784 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 105.5" "Cancer enhanced" "Detected in all" "melanoma: 88.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013115, HPA066915" Enhanced Enhanced Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "CAB013115: AB_2536375, HPA066915: " "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-1)" "prognostic unfavourable (9.94e-4)" "prognostic unfavourable (8.61e-5)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (5.38e-3)" "unprognostic (4.69e-3)" "prognostic unfavourable (1.46e-10)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (6.75e-2)" 10.7 7.6 4.5 20.8 6.5 18.7 11.5 4.2 4.3 12.6 11.6 3.5 6.0 6.1 10.7 6.4 13.6 10.8 12.6 10.1 5.4 2.2 8.3 16.7 19.5 12.2 6.0 2.0 14.2 8.3 5.2 4.2 49.0 7.3 10.8 9.1 51.2 9.3 9.9 10.8 14.6 9.3 11.8 5.0 12.5 10.1 7.8 5.1 39.3 9.5 10.7 14.7 16.7 10.1 9.3 10.8 5.2 3.9 4.5 7.6 4.3 16.5 8.9 19.6 10.9 4.0 5.2 36.2 20.6 10.8 25.6 24.0 18.7 15.9 15.7 15.5 7.6 10.6 14.9 9.0 26.1 18.5 14.6 18.1 14.8 7.1 1.3 14.3 13.1 2.7 2.3 17.3 6.0 12.9 17.2 14.3 17.8 12.7 29.6 12.1 7.8 13.3 29.0 18.9 11.8 7.4 16.2 8.1 10.5 23.5 8.6 105.5 18.6 10.5 7.2 17.7 17.2 13.6 15.0 8.2 9.4 19.6 10.0 10.5 15.2 5.2 3.6 3.1 7.0 3.9 7.0 9.3 3.2 5.0 2.7 6.1 3.0 5.3 1.7 4.5 1.6 10.8 7.6 4.3 4.5 6.5 4.2 4.3 5.4 2.2 6.0 2.0 7.3 5.1 CDK20 "CCRK, p42" ENSG00000156345 "Cyclin dependent kinase 20" Q8IZL9 9 87966441-87974753 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SCLC-21H: 14.4;THP-1: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 7.2" "Group enriched" "Detected in many" 7 "NK-cells: 7.2;T-cells: 5.0" "Low region specificity" "Detected in all" "HPA007666, HPA027379, HPA027401" Enhanced Supported Nucleoplasm Nucleoplasm "HPA007666: AB_10600002, HPA027379: AB_10599939, HPA027401: AB_10601553" "unprognostic (4.60e-2)" "unprognostic (6.48e-2)" "unprognostic (1.69e-2)" "prognostic favourable (2.59e-4)" "unprognostic (2.32e-1)" "unprognostic (4.33e-3)" "unprognostic (2.81e-4)" "unprognostic (6.33e-2)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "unprognostic (2.83e-3)" "unprognostic (4.04e-2)" "prognostic favourable (2.12e-5)" "unprognostic (8.24e-3)" "unprognostic (5.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.42e-2)" 2.6 16.2 10.8 2.4 13.0 1.6 4.1 8.7 17.1 8.7 5.0 6.1 5.1 5.3 7.2 6.0 2.8 19.5 5.6 3.0 8.6 10.7 8.2 3.2 4.0 2.0 5.8 14.3 9.5 4.8 7.6 10.8 3.1 9.3 6.1 3.4 7.7 3.6 8.6 2.1 3.6 7.6 5.5 3.1 1.6 3.7 17.7 5.2 0.8 6.8 1.2 1.1 6.3 3.0 0.1 0.8 0.4 0.8 7.2 5.0 1.3 2.3 3.0 2.4 7.6 1.7 2.4 1.0 2.1 4.2 5.8 5.4 0.7 3.5 0.0 3.3 3.5 3.1 0.0 2.1 2.4 5.9 2.4 0.0 1.9 0.0 7.4 2.8 3.3 1.9 4.4 9.2 3.8 0.0 0.3 0.0 1.7 7.0 1.9 0.8 1.9 1.1 0.0 0.0 0.1 7.4 2.0 14.4 4.0 2.5 3.0 3.6 3.3 21.6 0.0 2.6 1.0 0.5 2.4 3.8 3.6 0.0 9.3 1.9 2.7 0.0 0.7 0.4 1.3 0.8 0.5 0.0 3.0 1.9 0.7 0.1 5.0 3.2 0.1 7.2 0.7 0.8 2.7 1.3 10.8 13.0 8.7 17.1 8.6 10.7 5.8 14.3 9.3 5.2 CDK3 ENSG00000250506 "Cyclin dependent kinase 3" Q00526 17 76000906-76005999 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007420 Uncertain Approved Cytosol Cytosol "HPA007420: AB_1078490" "unprognostic (6.77e-2)" "unprognostic (1.26e-1)" "unprognostic (3.69e-2)" "unprognostic (1.87e-3)" "unprognostic (6.41e-2)" "unprognostic (1.10e-3)" "unprognostic (1.61e-2)" "unprognostic (1.56e-1)" "unprognostic (8.12e-3)" "unprognostic (1.34e-1)" "unprognostic (9.80e-5)" "unprognostic (1.19e-2)" "unprognostic (6.75e-7)" "unprognostic (4.25e-2)" "unprognostic (1.63e-2)" "unprognostic (4.68e-1)" "unprognostic (4.47e-4)" 4.1 3.7 2.7 4.7 2.4 5.5 4.7 4.2 2.4 4.9 4.8 6.5 5.6 5.7 4.0 5.0 4.8 2.6 2.8 3.0 5.9 13.0 5.3 5.5 3.0 6.7 5.9 4.2 8.3 5.0 10.3 5.3 5.2 4.5 0.9 14.7 9.1 4.1 3.9 8.8 5.2 5.6 8.2 5.4 3.8 5.1 1.2 1.8 1.5 1.5 1.7 2.7 1.6 4.2 7.7 11.5 6.0 6.8 8.0 23.9 5.2 3.4 5.9 5.5 6.0 8.8 6.3 4.6 4.5 9.7 9.2 3.9 3.8 3.2 14.8 13.2 15.3 6.0 5.6 4.6 13.5 7.2 8.5 5.2 4.2 6.4 5.8 4.5 3.7 10.7 5.3 20.4 5.7 8.4 9.9 5.0 5.9 5.4 14.0 8.3 22.4 3.5 11.3 2.5 15.5 9.3 5.4 15.9 9.4 6.7 5.5 9.5 7.1 5.9 4.8 4.7 3.9 0.0 1.5 0.0 2.1 1.0 0.2 1.2 1.6 1.2 1.8 0.3 2.7 0.5 1.5 1.7 0.6 1.6 2.7 1.6 CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 10 "HBEC3-KT: 125.1;LHCN-M2: 138.1;RH-30: 434.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" Cytosol "Nucleoplasm, Nuclear membrane, Nucleoli" "CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: " "unprognostic (8.88e-2)" "unprognostic (2.53e-1)" "unprognostic (5.27e-2)" "unprognostic (9.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "prognostic unfavourable (2.09e-7)" "unprognostic (7.39e-2)" "unprognostic (3.23e-3)" "unprognostic (2.93e-2)" "unprognostic (3.19e-2)" "unprognostic (9.10e-2)" "prognostic unfavourable (3.15e-5)" "unprognostic (3.32e-1)" "unprognostic (1.67e-1)" "unprognostic (3.64e-1)" "unprognostic (1.57e-2)" 32.2 43.1 13.8 22.2 15.7 24.0 45.0 13.1 17.9 36.3 28.2 20.1 22.8 15.2 51.4 28.1 29.9 31.0 32.3 27.4 14.5 12.1 24.0 36.9 26.8 26.4 18.3 13.7 61.4 54.4 18.9 34.2 25.0 16.0 37.2 26.9 26.2 29.3 24.1 27.8 25.6 20.7 34.1 13.5 27.2 23.9 24.6 17.5 29.2 54.3 32.1 27.5 33.6 30.9 29.6 25.5 2.6 19.9 15.8 32.1 22.2 9.3 10.8 14.3 12.7 13.1 11.5 9.5 5.4 17.6 23.8 19.8 15.4 8.9 13.6 9.7 8.4 7.2 19.7 125.1 18.1 6.7 9.1 12.7 7.3 10.8 15.4 14.4 8.8 11.3 9.2 14.6 16.8 15.3 13.5 11.7 138.1 13.5 13.7 11.7 16.8 11.0 12.4 434.6 12.6 7.4 14.7 12.9 12.1 9.5 7.2 14.4 9.6 17.5 6.9 11.2 10.5 12.6 10.9 5.8 9.5 20.9 10.3 13.3 13.4 1.7 14.3 2.6 26.2 19.9 27.0 29.6 23.1 23.7 21.0 28.1 32.1 28.5 1.2 15.8 12.0 25.5 16.6 22.2 13.8 15.7 13.1 17.9 14.5 12.1 18.3 13.7 16.0 17.5 CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053812-151058530 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB008909: , HPA064535: " "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (5.67e-3)" "unprognostic (1.05e-2)" "unprognostic (1.22e-1)" "unprognostic (5.78e-3)" "unprognostic (6.25e-3)" "unprognostic (3.35e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" 4.5 11.3 24.4 6.9 30.4 6.1 5.3 13.6 36.1 5.3 6.1 6.7 4.5 7.9 4.5 17.4 6.5 5.0 6.2 5.8 25.0 19.7 9.0 7.7 5.3 6.0 15.4 15.4 3.2 5.8 8.9 7.9 5.3 20.8 5.8 6.3 3.2 6.0 6.3 5.7 6.5 6.2 6.0 8.6 5.2 5.7 3.1 7.7 6.8 6.0 3.6 6.9 6.7 3.1 6.6 21.5 9.0 21.7 9.5 14.9 10.6 11.6 14.0 13.1 21.3 14.5 10.7 6.5 7.7 12.8 15.2 12.6 9.9 10.9 11.5 27.7 9.5 8.3 21.0 11.8 7.0 9.1 12.5 12.6 12.3 9.8 9.6 10.2 23.7 11.5 8.8 12.5 3.9 10.2 12.8 8.4 15.2 22.6 27.4 20.8 14.4 22.1 13.4 5.4 12.8 13.2 8.8 8.3 35.7 11.1 13.7 14.6 6.4 9.0 8.6 15.0 3.9 11.2 14.4 19.6 21.4 4.5 23.6 14.7 26.8 7.8 19.0 9.0 6.9 21.7 5.4 6.6 6.8 6.8 21.5 5.9 5.1 6.2 2.8 9.5 16.4 12.8 14.9 10.6 24.4 30.4 13.6 36.1 25.0 19.7 15.4 15.4 20.8 7.7 CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836594 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.6" "Cell line enhanced" "Detected in many" "MOLT-4: 91.7;REH: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB004363: AB_627242, HPA002637: AB_1846432" "unprognostic (1.29e-1)" "unprognostic (5.98e-3)" "unprognostic (9.07e-2)" "unprognostic (2.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.24e-2)" "unprognostic (3.39e-1)" "unprognostic (2.42e-3)" "unprognostic (7.19e-2)" "unprognostic (7.78e-3)" "prognostic unfavourable (3.86e-6)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.09e-1)" "unprognostic (7.88e-2)" "unprognostic (1.93e-1)" "prognostic unfavourable (2.33e-5)" 6.6 11.3 6.0 9.1 7.5 22.5 5.9 2.4 6.0 7.8 10.0 9.6 5.7 7.5 6.0 5.9 8.5 4.6 7.8 6.6 6.9 4.2 6.5 7.5 7.3 7.4 7.0 5.2 5.0 10.0 25.7 4.2 20.5 7.5 6.1 9.2 4.4 10.9 6.1 2.0 11.6 9.4 9.8 7.5 6.3 10.8 5.4 8.0 74.6 4.3 9.2 10.3 6.7 9.0 3.6 5.6 6.5 4.8 3.9 7.1 2.3 6.0 2.8 7.8 5.0 2.3 2.6 1.6 6.3 3.9 3.1 3.0 7.7 4.7 4.7 3.6 4.2 3.8 4.3 9.0 7.4 10.3 3.0 11.8 5.4 7.4 1.4 7.3 0.5 2.5 4.9 4.2 20.0 1.2 11.2 13.0 5.6 1.2 91.7 0.7 2.4 2.6 44.8 27.6 7.9 4.3 0.1 4.1 26.8 0.7 2.1 3.7 0.1 12.0 4.6 10.3 16.1 4.0 12.6 7.0 0.1 6.3 1.5 25.0 13.6 4.9 1.9 6.5 5.2 3.9 5.9 2.0 5.5 5.6 4.0 3.6 7.1 4.0 1.1 3.9 4.8 5.6 2.8 2.3 6.0 7.5 2.4 6.0 6.9 4.2 7.0 5.2 7.5 8.0 CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932" Enhanced "CAB004364: AB_627243, HPA007932: AB_1078492" "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" "unprognostic (4.87e-2)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.49e-3)" "unprognostic (1.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.81e-2)" "prognostic unfavourable (3.09e-4)" "unprognostic (3.40e-2)" "prognostic unfavourable (9.42e-7)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-2)" 7.9 12.9 10.9 6.2 15.2 44.1 14.0 10.8 14.7 9.4 12.7 6.0 6.3 15.8 9.4 8.6 23.4 18.5 16.5 8.1 11.5 9.3 13.8 10.6 10.1 8.8 7.6 9.7 7.7 9.1 3.3 16.2 22.9 11.2 11.2 14.8 6.6 13.2 6.5 15.9 15.4 9.8 12.1 9.2 7.9 13.9 29.0 7.8 12.1 20.0 15.6 15.5 10.7 11.7 15.6 15.0 22.4 11.3 12.4 15.3 7.8 3.7 7.8 1.8 0.5 2.4 11.6 14.7 6.5 7.7 10.8 17.5 16.7 1.9 2.8 10.2 1.7 2.5 1.4 2.8 5.9 1.3 7.0 0.4 8.2 7.9 0.4 6.7 3.2 14.3 13.9 9.0 2.8 13.6 10.4 4.5 4.9 0.7 4.1 14.8 1.7 7.5 6.7 0.4 1.1 1.6 1.0 0.6 6.5 1.5 5.8 3.4 11.6 0.6 2.6 0.1 3.2 0.9 5.1 4.8 8.4 3.7 0.8 4.0 0.8 7.3 10.9 22.4 8.6 11.3 14.8 12.4 12.9 15.3 15.0 15.6 11.1 13.2 10.0 12.4 8.0 11.2 12.8 7.8 10.9 15.2 10.8 12.7 11.5 9.3 7.6 9.7 11.2 7.8 CDK8 K35 ENSG00000132964 "Cyclin dependent kinase 8" P49336 13 26254104-26405238 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044721 Approved Nucleoplasm Nucleoplasm "HPA044721: " "unprognostic (3.28e-3)" "unprognostic (2.25e-3)" "unprognostic (2.08e-1)" "unprognostic (3.88e-3)" "unprognostic (2.30e-2)" "unprognostic (1.05e-2)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (5.00e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-3)" "unprognostic (2.12e-1)" "prognostic favourable (9.23e-4)" "unprognostic (1.43e-2)" "unprognostic (1.88e-1)" "unprognostic (6.37e-2)" 7.6 8.8 10.1 10.4 8.5 5.2 5.6 26.9 11.3 5.9 24.0 6.0 13.8 13.8 11.2 6.5 10.0 7.0 11.2 7.6 8.3 7.3 9.4 10.4 6.7 5.2 7.8 7.9 6.1 12.7 8.4 10.2 10.6 8.2 7.8 11.2 4.6 9.0 19.2 9.7 6.1 15.0 12.7 6.0 6.4 11.7 16.3 9.9 12.8 6.4 6.9 7.2 15.5 11.0 1.9 1.7 3.4 1.6 1.0 2.1 1.3 6.8 5.6 11.4 11.6 6.0 7.5 7.0 13.2 9.1 9.8 7.1 16.3 9.6 7.3 5.8 6.8 8.4 13.1 8.9 12.4 16.8 7.2 13.8 4.6 5.6 4.2 21.6 7.9 5.4 8.5 7.4 12.4 7.1 21.4 0.0 8.8 7.3 16.5 10.2 9.1 7.0 10.4 11.3 5.0 5.7 6.4 9.7 5.7 5.6 10.7 9.7 3.8 9.9 7.3 6.3 8.0 11.5 7.1 5.6 9.9 13.4 3.9 9.1 7.4 0.4 0.9 3.4 1.1 1.6 1.9 1.0 1.5 2.1 1.7 1.9 2.1 1.7 0.0 1.0 1.2 1.0 0.6 1.3 10.1 8.5 26.9 11.3 8.3 7.3 7.8 7.9 8.2 9.9 CDK9 "C-2k, CDC2L4, PITALRE, TAK" ENSG00000136807 "Cyclin dependent kinase 9" P50750 9 127785679-127790787 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004216, HPA006738" Supported Approved "Nucleoplasm,Cytoplasmic bodies" Nucleoplasm "Cytoplasmic bodies" "CAB004216: AB_627245, HPA006738: AB_1078493" "unprognostic (3.60e-1)" "unprognostic (1.71e-1)" "unprognostic (5.44e-3)" "unprognostic (1.04e-3)" "unprognostic (1.93e-1)" "unprognostic (3.97e-2)" "unprognostic (2.07e-1)" "unprognostic (5.84e-2)" "unprognostic (2.66e-1)" "unprognostic (8.36e-2)" "unprognostic (1.24e-3)" "unprognostic (3.11e-2)" "prognostic unfavourable (8.92e-4)" "unprognostic (1.37e-1)" "unprognostic (1.00e-1)" "unprognostic (3.52e-2)" "unprognostic (8.78e-3)" 26.2 27.0 22.8 18.9 22.4 33.9 17.4 31.0 26.8 23.1 21.9 22.9 24.7 16.6 22.5 20.1 22.7 29.1 21.5 22.9 26.3 23.4 18.5 48.7 23.3 26.6 23.4 18.8 43.7 29.1 15.5 28.4 19.8 20.6 20.7 10.8 18.7 20.6 21.6 14.6 26.6 21.4 21.0 17.9 29.0 17.7 22.3 16.1 29.3 25.8 18.3 24.2 17.0 17.6 6.0 8.9 5.1 6.4 18.6 9.9 2.9 8.8 16.1 10.1 11.1 11.5 9.0 13.2 9.1 13.4 9.5 8.6 11.9 10.0 15.5 10.7 10.3 17.9 6.6 14.9 3.6 13.9 8.0 14.5 17.4 9.8 16.8 14.0 23.3 15.8 18.2 10.1 11.4 19.6 12.5 20.9 8.5 23.3 15.3 21.1 22.3 17.2 44.3 8.6 22.3 13.8 9.9 10.0 11.9 13.7 14.5 8.2 18.2 13.3 22.4 11.4 12.9 9.8 8.8 38.1 29.2 13.9 10.7 9.6 10.4 3.7 3.4 4.9 9.9 4.5 9.9 3.5 5.6 7.9 4.4 6.0 6.3 7.7 5.1 18.6 6.4 8.9 3.8 2.9 22.8 22.4 31.0 26.8 26.3 23.4 23.4 18.8 20.6 16.1 CDKAL1 FLJ20342 ENSG00000145996 "CDK5 regulatory subunit associated protein 1 like 1" Q5VV42 6 20534457-21232404 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "tRNA processing" Transferase "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "SCLC-21H: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057474 Uncertain Vesicles Vesicles "HPA057474: " "unprognostic (9.64e-2)" "unprognostic (7.23e-3)" "unprognostic (8.40e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (1.05e-1)" "unprognostic (1.51e-2)" "unprognostic (3.47e-2)" "unprognostic (4.25e-3)" "unprognostic (6.72e-3)" "unprognostic (1.61e-3)" "unprognostic (1.42e-1)" "unprognostic (3.73e-2)" "unprognostic (5.79e-3)" "unprognostic (3.11e-2)" "unprognostic (1.75e-2)" "unprognostic (1.83e-2)" "unprognostic (2.60e-2)" 18.5 9.8 10.9 18.0 12.2 14.7 13.9 24.1 10.6 16.6 11.4 14.6 9.6 8.1 19.4 12.1 12.1 13.5 11.4 10.8 9.0 7.8 10.8 9.7 11.9 13.4 12.4 7.7 16.6 14.1 12.0 29.9 12.6 11.2 10.8 12.0 14.3 15.7 11.0 22.2 15.0 11.4 13.7 13.4 13.9 11.7 11.4 13.8 22.9 17.1 13.6 19.4 13.2 12.6 8.1 5.4 3.3 11.2 12.0 9.7 3.6 2.9 1.8 4.2 5.4 2.4 3.2 4.4 3.0 2.8 4.5 6.0 3.3 2.6 6.9 7.7 2.6 2.9 5.6 3.1 6.1 12.4 3.1 5.9 3.1 4.4 3.1 5.8 4.1 2.9 3.3 4.3 4.0 4.1 7.6 2.8 3.3 2.4 7.3 6.9 2.9 2.0 4.3 5.6 6.5 5.8 3.3 66.0 3.9 3.4 5.5 4.4 4.0 2.9 4.0 5.3 3.7 2.1 5.6 4.5 11.9 6.1 1.9 3.3 8.9 1.5 3.6 3.3 7.8 5.9 6.5 8.1 7.7 7.7 4.9 7.8 9.7 8.6 1.9 12.0 11.2 5.4 8.2 3.6 10.9 12.2 24.1 10.6 9.0 7.8 12.4 7.7 11.2 13.8 CDKL1 KKIALRE ENSG00000100490 "Cyclin dependent kinase like 1" Q00532 14 50329404-50416461 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 16.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059605, HPA065919" Uncertain Enhanced Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA059605: , HPA065919: " "unprognostic (4.12e-3)" "unprognostic (3.22e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.02e-1)" "unprognostic (3.23e-3)" "unprognostic (9.36e-3)" "unprognostic (2.63e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (5.53e-8)" "unprognostic (1.21e-1)" "unprognostic (7.96e-2)" "unprognostic (9.39e-3)" "unprognostic (3.31e-3)" 7.1 2.1 7.5 1.8 5.1 0.9 3.0 2.7 20.2 14.1 5.9 1.6 2.5 8.4 12.1 2.3 2.6 16.4 2.6 2.9 7.1 2.4 18.8 1.1 4.3 3.0 2.0 12.3 10.5 2.0 1.4 1.4 4.9 2.9 4.0 5.7 1.6 2.5 8.4 1.7 3.0 3.0 7.7 3.1 3.7 2.0 1.9 1.4 1.3 5.0 6.1 2.1 7.0 5.6 5.7 1.3 6.0 2.5 3.8 6.7 2.6 6.0 4.8 0.6 2.4 6.5 7.8 0.3 2.1 3.8 2.2 2.5 1.9 5.7 0.4 2.6 4.6 4.2 0.9 0.6 2.5 6.6 2.3 6.4 2.1 1.7 7.3 5.8 3.5 1.7 3.5 4.5 10.0 8.4 2.6 2.6 1.0 0.3 1.9 3.1 0.7 2.3 0.7 2.8 1.8 6.9 2.3 1.1 1.3 2.4 16.5 0.6 0.2 4.9 2.6 5.7 2.9 5.6 4.7 0.8 0.4 0.4 0.9 6.1 6.9 6.0 2.5 4.4 6.3 2.3 6.2 4.6 4.4 6.7 1.3 5.7 3.4 3.7 1.4 3.8 0.3 1.2 4.1 2.6 7.5 5.1 2.7 20.2 7.1 2.4 2.0 12.3 2.9 1.4 CDKL2 "KKIAMRE, P56" ENSG00000138769 "Cyclin dependent kinase like 2" Q92772 4 75578005-75630716 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.7" "Cell line enhanced" "Detected in some" "A-431: 5.6;HEK 293: 3.7;HHSteC: 4.3;RPTEC TERT1: 8.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040672 Approved Nucleoplasm,Centrosome "Nucleoplasm, Centrosome" "HPA040672: AB_10794744" "unprognostic (2.07e-1)" "unprognostic (9.96e-2)" "unprognostic (6.91e-2)" "unprognostic (3.80e-5)" "unprognostic (3.43e-2)" "unprognostic (2.71e-2)" "unprognostic (1.59e-1)" "unprognostic (8.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-2)" "unprognostic (1.27e-1)" "prognostic favourable (6.88e-15)" "unprognostic (5.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-1)" "unprognostic (7.52e-2)" 0.7 2.4 7.1 1.2 11.1 0.7 1.2 7.7 13.2 1.7 2.0 6.2 0.0 1.0 1.7 2.3 2.3 4.1 1.4 1.3 5.1 6.7 11.8 0.7 9.2 1.3 7.1 7.0 3.8 1.6 5.7 8.9 0.7 12.5 2.0 2.4 3.4 1.2 2.0 0.7 0.9 0.9 1.5 7.4 0.9 1.5 27.7 6.1 0.0 6.9 0.0 2.0 1.1 0.9 0.4 0.0 0.2 0.0 0.0 1.6 0.1 5.6 0.7 0.3 0.0 0.3 0.3 0.0 0.3 1.7 2.4 1.9 0.5 1.2 0.1 0.9 0.1 0.8 0.0 0.5 2.2 0.2 3.7 0.0 0.2 0.0 4.3 0.0 0.1 1.4 2.1 0.4 0.8 0.1 0.0 0.4 0.9 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 8.1 0.3 3.0 2.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 2.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.4 1.6 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 1.2 0.1 7.1 11.1 7.7 13.2 5.1 6.7 7.1 7.0 12.5 6.1 CDKL3 NKIAMRE ENSG00000006837 "Cyclin dependent kinase like 3" Q8IVW4 5 134286350-134371047 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027751 Uncertain Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA027751: AB_10601256" "unprognostic (4.70e-2)" "unprognostic (2.15e-2)" "unprognostic (2.35e-1)" "unprognostic (1.48e-1)" "unprognostic (1.43e-1)" "unprognostic (3.98e-2)" "unprognostic (3.43e-3)" "unprognostic (5.93e-2)" "unprognostic (2.12e-3)" "unprognostic (1.49e-1)" "unprognostic (8.47e-4)" "unprognostic (2.82e-1)" "unprognostic (9.85e-4)" "unprognostic (8.33e-2)" "unprognostic (4.88e-2)" "unprognostic (7.10e-3)" "unprognostic (3.43e-3)" 2.5 2.7 7.0 2.2 7.1 1.6 2.5 7.0 8.5 2.6 2.4 5.9 5.5 2.3 3.9 5.3 2.6 3.7 2.6 6.6 6.1 6.5 4.5 2.8 2.2 2.5 8.0 4.3 3.0 2.4 3.2 6.5 2.2 8.6 2.8 2.6 3.9 2.0 3.2 7.5 2.7 2.5 4.6 8.4 2.7 2.2 33.4 9.3 1.3 3.9 2.1 3.0 2.8 2.2 1.5 2.7 1.0 1.1 1.4 4.0 1.3 1.0 2.2 3.3 2.2 5.6 4.8 1.4 3.0 2.7 1.4 3.3 2.0 1.5 2.8 1.9 1.9 0.9 2.7 1.9 2.7 3.0 2.1 1.5 2.4 3.4 3.4 0.6 1.0 2.2 4.9 4.1 1.3 1.3 1.5 1.2 3.6 1.1 2.1 8.3 2.2 1.0 3.6 1.4 0.8 1.8 1.0 5.0 1.5 2.2 0.6 3.6 1.9 1.7 1.0 2.7 0.6 3.6 1.0 3.4 4.5 5.4 4.1 2.2 2.1 0.0 0.9 1.0 0.9 1.1 4.0 1.5 1.4 2.5 2.7 1.0 3.8 3.8 0.2 1.4 0.4 1.6 2.3 1.3 7.0 7.1 7.0 8.5 6.1 6.5 8.0 4.3 8.6 9.3 CDKL4 ENSG00000205111 "Cyclin dependent kinase like 4" Q5MAI5 2 39175646-39229588 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 3.2;testis: 7.9" "Cell line enhanced" "Detected in some" "HAP1: 1.8;HL-60: 4.9;RT4: 3.3;SH-SY5Y: 6.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.6;T-reg: 3.2" "Group enriched" "Detected in many" 25 "B-cells: 1.6;T-cells: 3.2" "Low region specificity" "Detected in many" HPA067895 Uncertain "HPA067895: " "unprognostic (3.57e-2)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "unprognostic (7.46e-3)" "unprognostic (3.26e-2)" "unprognostic (4.26e-1)" "unprognostic (3.82e-2)" "unprognostic (6.13e-3)" "unprognostic (1.77e-2)" "unprognostic (8.43e-2)" "unprognostic (8.45e-4)" "unprognostic (8.59e-2)" "unprognostic (4.95e-1)" "unprognostic (3.08e-1)" "unprognostic (3.26e-2)" 0.3 1.1 0.3 0.0 0.6 0.0 0.3 0.1 0.7 0.2 0.0 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.5 0.9 0.2 0.0 0.4 0.1 0.2 0.3 0.3 0.0 1.6 1.2 0.4 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.3 7.9 0.3 0.1 0.1 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.5 0.4 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.1 0.0 0.1 0.3 0.7 0.3 4.9 1.1 0.3 0.0 0.1 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.2 3.3 0.6 6.6 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 CDKL5 "CFAP247, EIEE2, STK9" ENSG00000008086 "Cyclin dependent kinase like 5" O76039 X 18425583-18653629 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0" "Cell line enhanced" "Detected in many" "A549: 12.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 7.7;eosinophil: 2.1;neutrophil: 4.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002847, CAB011577" Supported Supported Nucleoplasm Nucleoplasm "CAB011577: AB_727019, HPA002847: AB_1080107" "unprognostic (7.01e-2)" "unprognostic (4.86e-2)" "unprognostic (1.41e-1)" "unprognostic (1.25e-4)" "unprognostic (1.17e-1)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" "unprognostic (9.63e-3)" "unprognostic (2.05e-3)" "unprognostic (1.66e-1)" "prognostic favourable (5.54e-4)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "unprognostic (2.67e-3)" "unprognostic (1.99e-1)" 3.3 3.2 8.0 1.8 24.7 3.2 4.3 3.9 28.0 5.4 2.7 7.7 1.8 1.5 4.5 2.8 5.2 2.8 3.1 5.0 8.0 3.7 6.3 2.2 6.9 1.4 3.5 13.2 6.7 4.5 6.2 5.0 5.4 5.9 6.7 2.2 2.0 3.9 4.4 3.0 3.5 1.9 4.0 5.7 2.3 4.9 14.0 5.7 1.6 5.1 0.8 2.1 5.6 4.6 0.7 1.0 7.7 1.0 0.5 0.6 0.2 1.7 12.3 3.5 3.1 3.3 4.5 2.5 2.0 3.8 2.8 3.2 4.0 2.3 1.9 0.4 1.3 0.5 4.0 3.0 5.9 0.5 2.6 0.0 7.1 3.1 1.6 0.1 0.8 2.6 3.1 6.8 7.1 1.3 0.1 1.9 4.2 1.7 0.8 0.8 7.1 3.0 0.7 3.8 0.1 2.4 8.9 0.7 4.4 4.5 1.1 2.2 1.6 0.7 7.3 4.3 1.9 7.9 1.5 0.3 0.1 0.3 2.4 0.5 4.2 7.7 1.0 2.1 0.6 0.6 0.3 0.2 0.4 0.3 0.3 0.7 0.6 0.6 4.7 0.5 0.6 1.0 0.2 0.2 8.0 24.7 3.9 28.0 8.0 3.7 3.5 13.2 5.9 5.7 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 80.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-reg: 16.1" "Group enriched" "Detected in all" 5 "NK-cells: 5.8;T-cells: 16.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: " "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavourable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavourable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 2.4 1.0 1.6 6.5 1.7 12.8 1.5 1.5 2.5 1.0 4.5 0.2 0.2 3.8 0.9 1.1 4.4 0.7 0.9 3.0 1.4 1.9 1.0 1.1 1.1 8.8 1.7 1.9 0.9 0.7 0.0 1.0 2.3 2.8 0.9 5.8 0.9 1.7 0.1 3.9 1.8 4.0 2.2 1.0 2.3 1.8 80.3 0.3 18.3 1.1 6.4 9.5 2.1 1.8 2.0 1.6 1.1 1.4 5.8 16.1 2.9 55.8 21.5 16.5 16.4 2.7 3.3 9.5 13.4 19.7 28.5 31.6 16.1 27.9 27.5 9.8 20.8 41.2 25.0 16.2 53.3 32.9 12.1 14.0 15.4 26.7 2.0 17.5 10.0 1.2 1.0 17.8 31.0 18.1 7.0 35.3 34.2 39.8 24.0 14.2 5.8 46.6 14.9 14.5 5.9 15.1 12.3 6.7 8.6 24.4 14.5 10.7 30.0 14.9 6.6 12.7 43.4 19.9 31.6 8.5 9.8 18.9 21.2 25.2 23.1 0.0 1.3 1.1 1.2 1.4 0.6 2.0 5.2 4.3 1.6 0.9 2.7 2.2 0.9 5.8 0.9 1.2 16.1 2.9 1.6 1.7 1.5 2.5 1.4 1.9 1.7 1.9 2.8 0.3 CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816954 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 142.1;seminal vesicle: 53.7" "Cell line enhanced" "Detected in some" "AF22: 22.6;ASC diff: 27.9;ASC TERT1: 10.8;HAP1: 8.0;NTERA-2: 8.4" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 20 "memory CD4 T-cell: 4.1;T-reg: 1.2" "Lineage enriched" "Detected in single" 41 "T-cells: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favourable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" 31.9 6.2 9.3 1.7 11.2 0.8 9.9 7.6 9.4 3.4 1.5 3.7 36.4 1.0 3.1 42.6 1.8 4.9 3.7 7.6 7.3 9.0 1.7 142.1 3.9 2.3 6.5 5.5 8.7 4.7 1.0 6.5 17.7 14.5 4.0 1.3 19.2 2.8 53.7 3.5 1.1 1.1 2.6 5.3 1.8 1.2 5.0 4.3 0.0 2.8 2.5 1.6 2.4 2.1 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 22.6 0.0 27.9 10.8 0.1 0.6 0.2 2.2 2.1 0.0 0.0 0.0 0.0 0.2 0.0 8.0 0.0 3.1 0.0 3.9 0.7 0.0 0.6 0.1 0.0 0.0 4.1 0.0 0.3 0.0 2.9 0.0 0.0 2.5 0.0 0.5 0.1 8.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 9.3 11.2 7.6 9.4 7.3 9.0 6.5 5.5 14.5 4.3 CDS1 ENSG00000163624 "CDP-diacylglycerol synthase 1" Q92903 4 84582979-84651338 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 48.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 20.6;hTCEpi: 25.8;SK-BR-3: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036187, HPA064546" Enhanced Approved "Nucleoplasm,Nuclear membrane" Nucleoplasm "Nuclear membrane" "HPA036187: AB_10601797, HPA064546: " "unprognostic (8.74e-2)" "unprognostic (7.11e-2)" "prognostic favourable (5.22e-4)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "unprognostic (3.11e-1)" "unprognostic (2.62e-1)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (6.67e-2)" "prognostic favourable (0.00e+0)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-1)" "unprognostic (2.06e-1)" 0.9 4.6 7.4 2.5 10.4 0.4 6.7 13.3 12.9 4.3 16.7 3.3 9.3 24.8 2.0 19.1 17.4 20.5 8.8 0.5 7.4 8.4 11.9 0.6 10.6 0.8 6.4 4.7 5.5 4.5 19.3 7.1 19.7 14.1 6.1 13.6 4.2 11.2 4.3 0.2 12.9 48.0 0.8 2.4 1.0 11.5 5.1 2.3 0.9 19.3 7.9 6.1 3.5 7.4 0.0 2.1 0.0 0.0 0.0 0.4 0.0 11.5 0.2 0.6 0.1 0.0 0.0 12.1 0.0 0.1 0.3 0.2 4.9 20.6 0.0 0.9 0.0 12.1 3.8 10.2 0.1 0.8 5.7 0.0 1.8 1.1 0.0 0.3 0.8 0.1 25.8 0.0 3.7 0.0 0.0 0.0 0.0 8.1 0.1 0.0 1.7 0.8 0.0 0.0 2.4 5.8 8.8 4.8 0.1 1.3 28.0 0.0 8.5 0.2 0.0 0.0 0.7 1.3 1.5 0.0 0.0 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.4 10.4 13.3 12.9 7.4 8.4 6.4 4.7 14.1 2.3 CDS2 ENSG00000101290 "CDP-diacylglycerol synthase 2" O95674 20 5126786-5197887 "Enzymes, Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "U-266/84: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019698 Approved Approved "Endoplasmic reticulum,Cytosol" 200000 "Endoplasmic reticulum" Cytosol "HPA019698: AB_1846464" "unprognostic (4.59e-2)" "unprognostic (1.98e-1)" "unprognostic (2.39e-1)" "unprognostic (3.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.48e-1)" "unprognostic (3.35e-3)" "unprognostic (1.65e-1)" "prognostic favourable (3.53e-9)" "unprognostic (8.89e-2)" "unprognostic (3.53e-1)" "unprognostic (1.38e-1)" "unprognostic (2.44e-1)" 14.8 16.1 22.2 9.9 25.5 12.1 12.1 36.0 34.5 12.7 11.8 21.4 6.7 5.9 12.9 9.8 10.5 12.5 10.0 26.6 22.0 34.0 16.9 14.2 14.5 10.9 26.7 24.0 10.9 7.2 20.6 15.6 11.1 28.3 15.9 12.3 19.8 8.0 19.7 9.4 6.2 9.9 20.2 16.2 9.8 10.6 13.0 12.5 8.1 14.2 4.6 13.6 11.6 8.2 7.6 7.9 28.3 9.7 6.5 11.1 11.7 9.4 10.6 10.6 5.5 6.3 5.8 4.9 5.2 10.7 8.6 12.5 6.5 9.3 7.2 2.6 9.7 13.6 8.6 10.9 9.2 7.6 3.0 8.3 3.0 10.0 5.9 5.4 3.1 5.0 6.1 11.3 4.4 11.5 4.0 9.3 8.0 1.6 10.6 2.0 5.1 3.2 9.2 8.6 3.3 5.5 9.2 4.4 6.2 5.8 9.9 13.4 6.1 2.5 8.4 6.2 4.9 5.5 5.2 8.1 59.6 6.0 2.8 4.2 3.7 24.1 9.7 11.5 10.0 8.0 10.6 7.6 10.2 11.1 7.9 7.4 8.0 7.8 28.3 6.5 7.3 6.3 11.1 11.7 22.2 25.5 36.0 31.6 22.0 34.0 26.7 24.0 28.3 12.5 CDY1 CDY1A ENSG00000172288 "Chromodomain Y-linked 1" Q9Y6F8 Y 25622162-25624902 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 47 "testis: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY1B ENSG00000172352 "Chromodomain Y-linked 1B" Q9Y6F8 Y 24045229-24048019 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "testis: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY2A CDY2 ENSG00000182415 "Chromodomain Y-linked 2A" Q9Y6F7 Y 18025787-18028597 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "epididymis: 3.8;testis: 6.0" "Cell line enriched" "Detected in single" 12 "U-266/84: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY2B CDY ENSG00000129873 "Chromodomain Y-linked 2B" Q9Y6F7 Y 17877410-17880220 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CELA3A "ELA3, ELA3A" ENSG00000142789 "Chymotrypsin like elastase family member 3A" P09093 1 22001656-22012539 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2051 "pancreas: 2541.2" "Cell line enriched" "Detected in single" 24 "MOLT-4: 21.1" "Cancer enriched" "Detected in some" 2497 "pancreatic cancer: 1481.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" Cytosol "HPA028086: , HPA045650: " "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" "unprognostic (1.79e-1)" "unprognostic (6.32e-2)" "unprognostic (2.67e-1)" 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.2 2541.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CELA3B "CBPP, ELA3B" ENSG00000219073 "Chymotrypsin like elastase family member 3B" P08861 1 21977021-21998642 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 196 "pancreas: 1614.4" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in single" 1218 "pancreatic cancer: 408.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" Cytosol "HPA028086: , HPA045650: " "unprognostic (2.89e-1)" "unprognostic (4.01e-3)" "unprognostic (6.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (6.40e-2)" 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 1614.4 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 5.9 5.3 8.2 3.0 2.3 3.2 0.9 0.6 4.9 1.7 1.3 2.5 1.5 2.2 1.1 1.8 1.7 1.7 5.3 2.7 5.4 2.6 1.4 1.6 1.0 0.5 0.0 2.4 4.1 2.4 4.9 3.9 1.3 1.9 3.2 2.3 2.4 1.4 0.0 2.4 2.5 5.5 0.4 2.5 2.1 1.5 1.3 3.5 3.6 0.9 4.2 0.0 3.6 3.1 1.7 3.4 0.8 0.3 2.5 2.8 3.6 2.9 1.6 2.3 1.0 4.8 4.7 2.4 1.8 4.7 0.6 5.1 2.5 1.8 3.1 3.0 2.0 3.7 2.2 2.8 1.4 5.9 3.2 3.0 8.2 2.3 1.7 5.3 2.9 0.9 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CERK "dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4" ENSG00000100422 "Ceramide kinase" Q8TCT0 22 46684411-46738261 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064699 Approved Vesicles Vesicles "HPA064699: " "unprognostic (2.93e-2)" "unprognostic (1.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavourable (4.75e-4)" "unprognostic (2.67e-2)" "unprognostic (1.49e-3)" "unprognostic (8.55e-2)" "unprognostic (3.60e-2)" "unprognostic (3.87e-1)" "unprognostic (1.35e-2)" "prognostic favourable (2.35e-4)" "unprognostic (2.26e-1)" "unprognostic (1.50e-3)" "unprognostic (1.27e-1)" "unprognostic (4.78e-1)" "unprognostic (3.38e-1)" "prognostic unfavourable (1.58e-4)" 10.6 15.5 10.6 16.7 10.8 14.5 12.9 29.3 21.7 10.8 14.6 9.8 15.8 24.9 14.1 7.5 10.0 15.3 18.9 36.5 11.4 16.8 15.2 12.1 10.6 19.1 21.7 13.1 22.7 23.2 7.2 33.3 7.9 23.9 8.2 12.2 12.3 11.8 11.6 12.8 11.9 25.1 12.5 10.2 14.5 14.0 6.0 6.5 39.2 16.1 8.7 19.5 10.7 17.4 2.0 4.9 3.6 6.9 2.0 16.4 3.6 9.3 5.6 27.4 8.6 15.8 12.0 2.5 16.4 12.8 9.4 6.6 8.2 3.1 13.0 7.7 17.5 6.1 11.5 7.4 9.6 4.6 12.5 5.8 14.2 10.7 11.0 18.2 1.5 9.9 9.6 10.2 3.5 27.9 4.3 16.9 17.2 0.7 12.3 9.1 12.4 6.2 23.0 31.1 14.8 5.6 0.1 25.6 23.3 8.0 3.9 17.2 4.3 13.9 25.3 19.5 10.4 14.3 23.7 17.6 21.2 8.2 20.7 10.4 15.8 0.6 2.6 3.0 9.4 6.0 16.4 1.8 9.9 9.0 4.5 2.0 5.8 5.4 3.6 2.0 6.9 4.9 8.6 3.6 10.6 10.8 29.3 21.7 11.4 16.8 21.7 13.1 23.9 6.5 CERS3 "LASS3, MGC27091" ENSG00000154227 "Ceramide synthase 3" Q8IU89 15 100400395-100544995 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 25.6;skin 1: 29.0;testis: 37.9" "Cell line enriched" "Detected in some" 6 "hTCEpi: 37.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 14.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 3.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006092, HPA024356" Approved Supported Nucleoplasm Nucleoplasm "HPA006092: AB_1079236, HPA024356: AB_1852721" "unprognostic (5.01e-3)" "unprognostic (3.43e-2)" "unprognostic (6.47e-4)" "unprognostic (2.35e-2)" "unprognostic (5.58e-2)" "unprognostic (1.68e-1)" "unprognostic (6.84e-3)" "unprognostic (3.23e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.31e-5)" "unprognostic (2.65e-1)" "unprognostic (4.74e-4)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.05e-3)" 0.4 0.0 0.4 0.4 0.4 0.0 1.9 0.4 0.4 6.0 0.4 0.4 0.4 0.0 0.4 0.4 25.6 0.3 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 0.0 0.4 3.6 0.4 0.4 29.0 0.4 0.4 0.4 0.4 0.0 37.9 0.4 0.4 0.4 0.4 8.5 0.4 11.2 0.0 0.0 1.5 0.6 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.1 0.2 0.2 0.0 0.7 0.3 0.0 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 CERS5 "FLJ25304, LASS5, MGC45411, Trh4" ENSG00000139624 "Ceramide synthase 5" Q8N5B7 12 50129306-50167533 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026589 Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA026589: AB_1852727" "unprognostic (1.59e-2)" "unprognostic (9.83e-2)" "unprognostic (5.17e-2)" "unprognostic (3.64e-2)" "unprognostic (3.02e-1)" "unprognostic (2.49e-3)" "prognostic unfavourable (4.63e-5)" "unprognostic (5.56e-2)" "unprognostic (1.65e-2)" "unprognostic (9.26e-2)" "unprognostic (1.88e-3)" "unprognostic (5.67e-2)" "prognostic unfavourable (9.33e-11)" "unprognostic (8.37e-2)" "unprognostic (1.03e-1)" "prognostic favourable (5.76e-5)" "unprognostic (3.26e-1)" 18.0 13.2 18.3 13.3 21.6 10.9 18.0 38.3 19.6 21.1 15.0 17.5 8.9 6.3 22.6 20.9 14.1 17.7 14.9 9.9 16.7 11.6 16.0 7.8 14.7 15.1 13.9 19.1 22.5 13.8 23.9 22.4 19.7 14.3 15.6 11.5 14.9 14.6 16.2 5.0 21.5 12.2 21.8 10.3 15.7 13.3 11.6 14.4 12.7 15.5 7.0 14.9 18.4 18.3 21.0 26.1 33.5 35.1 29.0 26.3 22.3 9.3 10.4 23.0 6.5 12.9 10.8 19.5 20.6 17.8 19.8 18.8 24.5 14.7 14.1 17.2 29.1 8.7 10.1 7.9 19.6 22.1 10.3 11.8 8.8 14.8 25.6 11.9 16.0 18.6 12.0 16.3 15.2 18.0 8.8 13.1 24.8 16.2 10.4 32.5 14.8 10.1 13.6 15.1 10.0 25.6 12.0 7.0 11.4 17.4 8.2 27.5 11.2 13.8 17.1 17.0 11.4 12.8 8.9 12.8 12.1 11.3 13.5 8.3 7.8 24.8 19.0 28.1 26.0 25.5 22.9 17.9 22.9 22.4 18.2 21.0 17.9 24.3 33.5 29.0 35.1 26.1 26.3 22.3 18.3 21.6 38.3 19.6 16.7 11.6 13.9 19.1 14.3 14.4 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 355.0" "Group enriched" "Detected in some" 5 "Hep G2: 93.9;THP-1: 101.2" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 18 "classical monocyte: 32.6;myeloid DC: 32.9" "Group enriched" "Detected in many" 20 "dendritic cells: 32.9;monocytes: 32.6" "Not detected" "Not detected" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" 40000000 "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavourable (9.92e-4)" 27.1 1.7 0.3 0.5 0.4 2.1 24.7 0.4 0.6 3.1 8.9 0.5 1.5 2.4 7.3 2.1 4.5 6.7 57.7 8.1 0.3 0.0 0.7 355.0 19.8 2.3 0.3 0.6 3.9 1.3 0.0 0.8 1.1 0.6 11.2 1.0 3.8 3.9 4.0 1.6 1.4 3.5 10.2 0.7 4.4 7.0 1.0 0.3 0.4 1.7 2.3 1.5 8.2 16.1 0.2 32.9 0.2 32.6 0.1 1.6 12.1 0.0 0.6 0.0 0.0 14.1 0.0 0.4 0.0 0.0 0.0 0.0 6.5 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 93.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 101.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 20.3 0.0 0.0 32.6 0.1 1.3 1.8 0.5 0.2 0.2 1.6 32.9 0.2 0.2 0.4 0.2 0.1 0.4 1.7 0.1 12.1 0.3 0.4 0.4 0.6 0.3 0.0 0.3 0.6 0.6 0.3 CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "esophagus: 46.7;intestine: 146.9;liver: 78.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA018897 Enhanced Approved "Golgi apparatus,Cytosol" 7500000 "Golgi apparatus, Cytosol" "HPA018897: AB_1846558" "unprognostic (8.15e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-3)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (6.93e-2)" "unprognostic (7.99e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-2)" "prognostic favourable (1.50e-5)" "unprognostic (8.01e-2)" "unprognostic (1.53e-1)" "unprognostic (4.14e-2)" "unprognostic (1.38e-1)" 5.8 15.3 8.5 8.8 11.7 2.4 5.1 13.0 15.9 9.5 42.3 12.1 11.2 146.9 7.0 11.9 46.7 6.1 14.5 15.2 7.4 6.6 22.5 78.6 6.7 4.6 8.2 10.7 8.4 12.0 10.0 6.8 7.3 10.3 9.7 42.6 13.0 12.7 7.9 11.6 8.9 117.3 10.4 5.6 7.8 10.9 8.5 8.2 9.0 11.7 14.1 12.1 7.6 11.6 6.9 8.9 5.0 10.6 7.9 10.7 5.2 6.8 9.0 9.5 12.7 9.4 8.8 7.2 7.8 12.6 9.2 11.7 9.7 11.4 8.0 7.8 10.2 17.8 6.9 19.7 7.2 7.1 9.6 7.9 5.1 18.2 13.3 10.3 13.8 12.7 37.3 13.0 21.9 6.8 11.0 5.9 15.5 4.3 9.1 8.6 5.1 9.1 10.8 9.6 9.4 26.1 12.0 6.2 8.1 25.5 6.4 6.6 11.1 12.8 8.4 12.1 6.5 7.5 5.9 11.9 14.2 9.5 18.7 8.1 9.1 4.7 10.4 4.7 10.1 7.8 9.2 6.1 7.7 10.7 8.9 6.9 9.5 8.6 5.0 7.9 10.6 7.7 6.8 5.2 8.5 11.7 13.0 15.9 7.4 6.6 8.2 10.7 10.3 8.2 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961237-66975148 "Enzymes, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8;liver: 26.7" "Cell line enhanced" "Detected in many" "AN3-CA: 8.9;Daudi: 9.8;U-937: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" 1200000 "Nuclear membrane, Endoplasmic reticulum" "HPA041008: , HPA041307: " "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favourable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.5 0.1 0.8 13.3 1.3 0.2 1.0 1.6 1.3 0.6 40.7 0.7 1.4 16.8 0.4 0.7 2.2 1.5 3.0 0.7 1.5 1.0 6.8 26.7 0.9 0.2 0.8 1.1 0.5 7.8 0.0 1.1 0.4 2.2 0.4 17.9 1.1 5.9 0.6 12.9 0.5 41.8 0.5 0.9 0.2 4.6 0.9 0.6 0.5 0.4 2.4 0.5 0.4 0.3 0.7 0.6 2.7 0.6 0.3 0.9 0.2 0.5 3.5 0.4 8.9 0.3 0.2 1.4 0.3 0.2 0.4 0.6 0.5 4.4 9.8 3.0 0.0 0.7 1.4 0.7 0.2 1.6 6.5 4.9 1.4 2.9 0.1 1.1 0.7 0.4 1.1 1.0 0.2 0.0 3.1 2.1 0.4 1.4 1.6 1.7 1.5 0.6 1.5 0.8 1.5 0.1 0.5 0.5 1.0 0.3 6.7 0.2 5.9 7.5 0.4 0.5 2.8 0.8 0.2 1.1 4.0 1.4 0.3 8.3 0.3 0.6 0.6 2.7 0.3 0.3 0.5 0.5 0.6 0.4 0.6 0.7 0.9 0.6 2.0 0.3 0.4 0.3 0.9 0.2 0.8 1.3 1.6 1.3 1.5 1.0 0.8 1.1 2.2 0.6 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "liver: 461.5" "Cell line enhanced" "Detected in some" "ASC diff: 6.0;ASC TERT1: 5.8;CAPAN-2: 6.9;fHDF/TERT166: 11.3;HSkMC: 18.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" 878700000 180000000000 "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: , HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favourable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavourable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 9.3 1.0 0.3 4.1 0.4 0.3 2.4 0.2 0.4 1.3 9.0 0.4 0.9 3.2 0.5 3.7 2.2 4.0 8.9 3.3 0.2 0.0 16.1 461.5 2.5 2.1 0.7 0.1 2.8 5.8 0.4 1.0 4.0 1.0 4.0 1.6 2.6 3.1 0.3 0.5 0.5 4.7 2.6 0.6 0.8 4.1 1.4 0.3 0.3 1.8 0.5 1.7 1.6 0.4 0.1 1.6 0.0 0.8 0.0 0.2 0.0 0.0 1.8 0.1 0.1 6.0 5.8 0.0 0.0 0.3 1.5 0.6 0.0 6.9 0.1 5.1 11.3 0.0 0.0 1.9 1.4 0.4 0.3 0.4 0.3 0.5 0.0 0.7 0.1 18.7 0.1 0.9 0.6 0.2 0.2 0.7 0.1 0.1 0.1 0.4 0.3 0.1 0.2 0.4 0.2 1.6 0.0 0.0 0.0 0.5 1.2 0.2 0.0 0.2 0.0 0.2 0.5 0.3 0.3 0.5 1.9 0.5 3.1 0.5 0.5 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.3 0.4 0.2 0.3 0.2 0.0 0.7 0.1 1.0 0.3 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109802179 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "kidney: 90.7;liver: 198.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 28.9;Hep G2: 45.8;HSkMC: 19.0;RPTEC TERT1: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" 11000000000 "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavourable (6.06e-4)" 9.5 13.2 1.5 2.3 1.4 0.0 3.9 0.9 2.5 5.0 4.1 1.1 2.9 4.9 5.0 12.0 4.4 9.7 9.3 6.2 1.6 0.8 90.7 198.4 7.2 3.1 1.8 0.7 10.6 7.6 0.5 3.8 3.2 2.6 3.9 0.7 6.8 3.6 3.6 1.4 0.5 4.6 3.0 3.0 7.8 1.7 3.6 1.6 0.5 5.3 2.3 1.4 3.8 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.0 28.9 0.0 9.2 0.0 0.0 0.0 0.0 0.0 9.7 0.3 0.0 0.1 45.8 2.0 0.0 0.0 19.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 51.2 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.4 0.9 2.5 1.6 0.8 1.8 0.7 2.6 1.6 CFLAR "c-FLIP, CASH, CASP8AP1, Casper, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116104-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "neutrophil: 79.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: AB_10696204" "unprognostic (4.61e-2)" "unprognostic (5.32e-2)" "unprognostic (2.49e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "prognostic favourable (2.79e-4)" "unprognostic (7.46e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (3.08e-2)" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (7.83e-2)" "unprognostic (9.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-2)" 35.4 17.6 13.7 29.8 17.4 66.8 31.6 26.9 12.6 20.5 25.7 13.5 31.3 17.5 24.7 27.6 21.0 19.2 22.1 58.1 14.7 7.7 24.9 18.9 58.5 34.3 16.8 8.9 14.6 14.3 9.1 18.7 28.3 12.6 23.2 17.7 20.9 21.8 27.4 113.7 16.7 26.8 30.5 13.8 35.7 19.4 10.9 14.8 17.2 31.2 26.2 31.4 24.1 33.7 5.3 6.6 79.2 12.6 8.7 11.8 7.8 5.1 10.6 7.6 4.5 23.6 18.1 9.4 13.1 22.9 8.7 10.6 12.2 19.4 1.4 12.5 15.2 3.8 2.4 9.9 13.9 38.8 7.4 7.8 9.1 19.8 16.5 5.8 25.9 19.7 9.8 14.6 12.9 44.0 26.3 32.7 15.7 4.3 2.7 23.2 2.6 8.0 2.8 1.8 11.1 10.8 10.7 1.7 3.0 8.8 7.8 10.3 5.5 10.9 47.7 18.2 7.6 6.7 6.4 54.5 17.9 8.7 12.9 4.7 9.0 16.3 12.1 13.5 11.7 12.3 10.3 5.3 10.1 11.0 6.6 4.0 6.4 8.3 79.2 8.7 12.6 4.6 11.8 7.8 13.7 17.4 26.9 12.6 14.7 7.7 16.8 8.9 12.6 14.8 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "Cystic fibrosis transmembrane conductance regulator" P13569 7 117465784-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 103.0" "Group enriched" "Detected in some" 22 "CACO-2: 12.5;MOLT-4: 47.0;U-266/70: 25.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Region enriched" "Detected in many" 5 "olfactory region: 6.3" "CAB001951, HPA021939" Enhanced "CAB001951: , HPA021939: AB_1846578" "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavourable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.2 0.4 10.5 0.4 0.0 0.3 0.3 0.3 2.5 19.8 0.1 0.8 10.5 0.6 2.1 0.4 0.4 15.8 0.3 0.4 0.3 1.1 1.4 5.7 0.1 0.5 0.1 0.3 103.0 0.0 0.3 0.1 0.1 1.5 12.5 0.1 22.4 0.1 0.3 1.1 24.2 0.3 0.7 0.3 0.6 0.9 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.3 0.4 0.3 0.5 0.1 0.1 0.1 CGAS "C6orf150, cGAS, MB21D1" ENSG00000164430 "Cyclic GMP-AMP synthase" Q8N884 6 73413515-73452276 "Enzymes, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity" "DNA-binding, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 32.0" "Cell line enhanced" "Detected in many" "RH-30: 21.2;RPMI-8226: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA031700, HPA031702" Enhanced Approved "Centriolar satellite,Cytosol" "Centriolar satellite" Cytosol "HPA031700: AB_10601693, HPA031702: " "unprognostic (2.49e-1)" "unprognostic (2.36e-1)" "unprognostic (4.61e-2)" "unprognostic (4.95e-2)" "unprognostic (2.49e-2)" "unprognostic (1.81e-1)" "unprognostic (4.84e-3)" "unprognostic (1.01e-2)" "unprognostic (9.80e-2)" "unprognostic (4.25e-2)" "unprognostic (2.20e-2)" "unprognostic (2.77e-1)" "prognostic unfavourable (2.27e-7)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (1.86e-1)" "unprognostic (2.78e-1)" 6.5 2.0 2.9 10.5 4.5 18.5 8.1 1.2 3.9 4.7 3.7 3.4 2.1 4.1 5.5 2.8 5.3 3.9 4.3 3.2 2.8 2.9 2.5 1.9 9.6 11.8 7.2 0.6 3.4 3.8 2.3 1.8 4.8 4.4 6.6 3.1 2.2 4.2 2.9 1.9 1.8 5.2 3.6 4.7 12.8 3.5 1.7 4.3 6.2 3.9 4.2 15.5 6.6 32.0 6.3 12.5 13.3 12.9 3.0 6.0 3.9 8.8 3.0 0.0 0.1 0.6 1.3 0.0 4.4 1.9 5.8 6.4 9.8 6.7 0.1 9.7 2.1 4.6 4.9 0.0 6.2 14.7 0.0 7.7 3.8 0.0 2.1 5.9 5.4 0.8 1.6 5.7 0.0 1.7 0.0 18.4 4.2 3.6 0.0 13.4 2.9 5.4 11.5 21.2 22.3 0.0 3.7 0.1 0.0 7.8 0.2 4.6 0.0 16.0 2.0 0.0 4.3 3.9 0.1 4.0 8.7 0.1 0.0 8.5 5.8 13.3 9.2 13.2 4.6 12.9 3.6 6.3 6.0 4.6 5.4 4.8 1.4 2.6 5.8 3.0 7.8 12.5 5.8 3.9 2.9 4.5 1.2 3.9 2.8 2.9 7.2 0.6 4.4 4.3 CHAC1 MGC4504 ENSG00000128965 "ChaC glutathione specific gamma-glutamylcyclotransferase 1" Q9BUX1 15 40952962-40956519 "Enzymes, Predicted intracellular proteins" "Apoptosis, Neurogenesis, Notch signaling pathway, Unfolded protein response" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 53.0;salivary gland: 39.9;skeletal muscle: 52.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 34.7;HHSteC: 26.5;hTCEpi: 42.0;SK-MEL-30: 29.6;U-266/70: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 1.8" "Group enriched" "Detected in many" 6 "B-cells: 1.8;monocytes: 1.1;T-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042708, HPA043505" Approved Approved Mitochondria Mitochondria "HPA042708: , HPA043505: " "unprognostic (6.04e-3)" "unprognostic (2.81e-2)" "unprognostic (7.47e-2)" "unprognostic (2.84e-3)" "unprognostic (6.57e-3)" "unprognostic (2.00e-2)" "unprognostic (5.59e-2)" "unprognostic (2.43e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (3.11e-1)" "unprognostic (1.51e-1)" "prognostic unfavourable (2.23e-7)" "unprognostic (1.37e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-2)" "unprognostic (3.91e-2)" 6.0 1.0 2.6 1.5 2.1 1.7 1.0 1.7 5.6 1.1 1.9 0.3 1.1 1.9 1.1 1.8 18.6 1.5 5.7 2.2 2.6 4.8 3.1 14.1 1.5 1.1 2.6 2.2 11.3 53.0 0.9 1.3 1.1 6.2 1.5 1.1 0.2 39.9 1.3 52.4 1.3 1.5 1.1 5.3 1.1 11.2 0.9 1.0 0.0 1.7 4.7 4.6 2.7 2.7 1.8 0.1 0.2 1.1 0.0 1.3 0.2 2.8 1.9 0.5 8.7 1.4 1.0 3.5 16.8 34.7 1.8 5.0 4.6 0.7 0.8 1.3 1.5 1.8 3.8 1.3 1.3 3.2 0.7 0.7 0.5 0.0 26.5 2.2 0.0 11.8 42.0 5.5 7.6 1.7 2.3 4.0 1.5 1.6 1.6 0.0 1.6 6.5 1.4 0.0 3.8 0.9 1.0 1.7 2.5 0.5 3.0 29.6 1.1 15.9 0.5 0.3 5.2 0.4 3.0 26.0 5.5 3.3 1.6 3.1 3.9 0.0 0.4 0.0 1.3 0.4 0.0 1.8 0.2 0.8 0.1 0.0 0.0 1.0 0.2 0.0 1.1 0.0 0.0 0.2 2.6 2.1 1.7 5.6 2.6 4.8 2.6 2.2 6.2 1.0 CHAC2 GCG1 ENSG00000143942 "ChaC cation transport regulator homolog 2" Q8WUX2 2 53767792-53775196 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049235 Approved Approved Cytosol Cytosol "HPA049235: " "unprognostic (2.22e-1)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (3.91e-3)" "unprognostic (1.61e-2)" "unprognostic (4.74e-3)" "prognostic unfavourable (3.80e-7)" "unprognostic (5.52e-2)" "unprognostic (1.74e-2)" "unprognostic (1.30e-2)" "unprognostic (1.36e-2)" "unprognostic (3.09e-2)" "unprognostic (4.28e-6)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" 7.2 8.6 6.5 7.1 6.2 9.3 3.6 4.3 4.4 2.6 6.8 2.1 7.7 11.4 2.4 4.4 8.4 1.8 5.3 10.3 6.2 6.1 8.3 9.8 3.4 9.6 5.0 4.2 1.8 4.8 1.5 6.7 1.7 6.9 2.8 6.1 2.8 4.1 4.6 9.8 2.0 9.0 3.5 4.8 10.2 7.0 16.4 3.7 9.5 3.7 4.2 9.8 5.7 5.1 6.6 2.5 1.8 0.9 1.4 6.7 3.0 18.8 6.3 6.7 5.9 3.4 1.7 1.4 8.7 1.7 6.2 7.4 4.4 4.9 16.0 12.7 3.7 6.8 15.2 10.3 10.9 33.8 13.3 12.7 8.5 7.1 5.2 15.0 5.8 2.1 3.1 11.5 8.8 12.1 13.0 9.5 8.1 6.1 17.7 12.6 8.7 11.3 13.6 14.3 16.3 8.6 5.1 8.4 2.3 10.1 7.5 4.0 4.6 5.9 5.3 3.6 13.1 14.0 14.0 9.4 12.1 13.7 5.0 18.9 5.0 1.8 0.5 1.1 5.2 0.9 5.5 6.6 5.7 5.8 1.1 5.4 6.7 6.1 1.4 1.4 0.7 2.5 5.1 3.0 6.5 6.2 4.3 4.4 6.2 6.1 5.0 4.2 6.9 3.7 CHAT ENSG00000070748 "Choline O-acetyltransferase" P28329 10 49609095-49665104 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Acyltransferase, Transferase" "Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.4;placenta: 10.4" "Cell line enriched" "Detected in some" 11 "NB-4: 15.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "basal ganglia: 5.4" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 18.4" "Group enriched" "Detected in many" 4 "basal ganglia: 7.7;pons and medulla: 8.1" "CAB002313, HPA048547, CAB079053" Supported Supported "CAB002313: AB_563661, CAB079053: , HPA048547: " "unprognostic (2.34e-2)" "unprognostic (6.10e-2)" "unprognostic (5.28e-2)" "unprognostic (6.96e-2)" "unprognostic (2.80e-2)" "unprognostic (3.98e-1)" "unprognostic (1.09e-1)" 0.2 0.0 0.2 0.3 5.4 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.2 1.6 0.2 0.5 0.2 0.0 0.2 0.2 0.2 0.6 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.9 0.0 0.2 10.4 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.2 1.1 0.2 0.4 0.2 0.0 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.6 1.0 0.3 0.2 0.6 1.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 15.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.7 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 1.3 0.0 0.0 0.2 0.3 0.4 0.1 0.5 0.3 1.0 0.4 0.1 0.6 0.5 0.3 0.0 0.6 0.1 1.0 0.2 0.0 0.2 5.4 0.2 0.2 0.2 0.6 0.2 0.2 0.2 0.2 CHD1 ENSG00000153922 "Chromodomain helicase DNA binding protein 1" O14646 5 98853985-98928957 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease mutation, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022236 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "HPA022236: " "unprognostic (2.63e-1)" "unprognostic (2.31e-1)" "unprognostic (1.09e-2)" "unprognostic (4.11e-2)" "unprognostic (7.79e-2)" "unprognostic (7.15e-2)" "unprognostic (6.50e-2)" "unprognostic (1.00e-2)" "unprognostic (1.79e-1)" "unprognostic (2.88e-1)" "unprognostic (4.94e-2)" "unprognostic (3.15e-1)" "prognostic unfavourable (7.25e-6)" "unprognostic (2.69e-1)" "unprognostic (3.33e-1)" "unprognostic (1.52e-1)" "unprognostic (1.17e-1)" 13.0 7.4 5.5 15.8 7.5 41.7 10.2 14.9 5.5 9.4 9.3 4.7 7.9 6.6 11.3 7.5 7.6 10.8 10.6 6.8 4.9 3.1 7.3 10.1 12.1 8.8 8.8 3.2 18.1 8.3 9.3 12.0 11.1 6.4 7.7 7.4 5.6 8.1 11.5 13.2 8.2 12.3 8.3 7.2 17.2 8.6 12.0 7.4 70.1 8.1 5.5 9.3 10.4 11.3 10.1 7.1 16.7 8.2 8.1 8.4 2.2 11.4 10.5 24.8 16.8 8.4 8.7 21.7 11.9 7.8 9.7 12.6 13.1 8.9 9.7 11.6 6.9 9.6 19.4 13.1 20.3 15.2 14.6 17.2 12.6 9.9 9.3 16.5 13.4 7.5 5.4 16.8 17.0 11.7 20.7 15.0 9.7 9.2 32.8 7.2 16.7 12.8 27.9 17.4 14.6 8.5 11.0 11.6 9.9 15.3 8.0 19.3 7.7 11.4 13.1 20.8 11.2 13.0 21.0 10.5 11.0 20.7 11.4 16.6 12.5 11.4 8.2 10.7 6.5 7.5 8.2 10.1 6.1 6.1 7.1 9.4 8.4 6.6 16.7 8.1 7.1 5.2 6.3 2.2 5.5 7.5 14.9 5.5 4.9 3.1 8.8 3.2 6.4 7.4 CHD1L ALC1 ENSG00000131778 "Chromodomain helicase DNA binding protein 1 like" Q86WJ1 1 147242641-147295766 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027789, HPA028670" Enhanced Supported Nucleoplasm Nucleoplasm "HPA027789: AB_10601099, HPA028670: AB_10601257" "unprognostic (1.07e-1)" "unprognostic (3.93e-2)" "unprognostic (1.97e-1)" "unprognostic (3.49e-1)" "unprognostic (1.78e-1)" "unprognostic (2.58e-2)" "prognostic unfavourable (3.07e-4)" "unprognostic (1.86e-2)" "unprognostic (7.83e-2)" "unprognostic (1.39e-2)" "unprognostic (4.97e-2)" "unprognostic (8.21e-2)" "prognostic unfavourable (1.31e-9)" "unprognostic (5.51e-2)" "unprognostic (3.52e-1)" "unprognostic (2.74e-2)" "unprognostic (1.16e-1)" 11.2 12.2 16.1 14.1 16.5 26.9 18.2 23.0 20.0 9.8 16.1 29.5 6.4 18.4 16.0 12.2 10.4 13.4 12.5 9.2 17.3 13.6 11.8 26.1 13.7 16.1 27.3 12.6 9.5 18.5 12.6 17.9 11.8 18.2 13.2 20.0 11.6 9.5 11.9 12.0 15.9 20.9 18.4 24.7 21.3 12.9 27.8 22.2 18.5 8.9 9.4 16.9 8.5 11.9 15.3 19.0 7.6 8.3 8.2 9.1 9.0 19.2 16.7 19.2 12.2 13.5 13.2 15.9 17.3 14.7 16.3 15.4 16.1 13.4 25.1 8.1 17.3 18.4 16.2 18.9 14.4 24.9 22.7 24.1 13.4 41.1 14.3 31.0 15.5 12.2 9.3 16.0 18.4 17.8 27.5 11.7 19.7 21.4 23.5 16.7 25.2 22.1 26.4 17.8 19.8 15.3 13.8 11.6 19.6 15.7 19.7 15.1 10.7 45.2 16.1 11.0 16.7 9.9 27.0 10.1 14.0 20.8 22.4 13.7 16.6 7.6 8.1 3.7 9.0 6.8 9.1 12.5 7.9 7.8 19.0 15.3 8.0 8.9 0.8 8.2 8.3 15.8 5.5 9.0 16.1 16.5 23.0 20.0 17.3 13.6 27.3 12.6 18.2 22.2 CHD2 "DKFZp547I1315, DKFZp686E01200, DKFZp781D1727, FLJ38614" ENSG00000173575 "Chromodomain helicase DNA binding protein 2" O14647 15 92900189-93028005 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060744, HPA060960" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA060744: , HPA060960: " "unprognostic (1.65e-2)" "unprognostic (2.43e-1)" "unprognostic (2.14e-2)" "unprognostic (5.98e-2)" "unprognostic (2.12e-2)" "unprognostic (3.10e-2)" "unprognostic (2.67e-2)" "unprognostic (7.85e-2)" "unprognostic (7.51e-3)" "unprognostic (1.14e-1)" "unprognostic (2.84e-1)" "unprognostic (1.79e-2)" "unprognostic (4.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-1)" "unprognostic (1.70e-2)" 23.7 16.6 18.7 23.6 21.1 66.7 21.8 35.1 22.8 24.1 19.9 19.7 17.6 15.7 26.1 31.9 20.3 18.4 16.8 15.3 18.5 15.7 17.7 17.6 30.4 25.2 22.1 13.9 26.3 20.9 27.5 41.9 33.1 19.1 22.4 16.1 22.1 21.2 19.9 24.3 25.2 24.3 20.3 30.8 26.9 20.8 20.4 22.4 39.5 28.8 11.3 37.4 34.7 19.0 25.5 17.2 34.5 6.3 8.0 17.5 4.6 10.7 5.8 15.9 7.0 9.9 24.5 12.2 10.1 10.3 6.8 8.5 7.4 14.1 2.6 8.5 8.7 16.0 9.2 9.9 9.6 0.0 5.4 12.7 11.7 6.4 13.4 13.4 10.0 15.4 12.2 8.1 16.5 11.5 13.2 30.3 10.3 6.6 6.9 7.0 10.1 6.6 10.0 14.5 14.5 7.1 14.5 8.8 9.5 17.5 6.4 13.1 7.2 11.4 18.4 5.6 7.4 4.8 6.4 28.9 11.6 11.0 8.6 8.1 4.8 14.9 6.3 15.0 12.9 3.3 11.8 25.5 12.6 10.1 3.3 23.4 17.5 12.5 34.5 8.0 5.8 17.2 12.3 4.6 18.7 21.1 35.1 22.8 18.5 15.7 22.1 13.9 19.1 22.4 CHD3 "Mi-2a, Mi2-ALPHA, ZFH" ENSG00000170004 "Chromodomain helicase DNA binding protein 3" Q12873 17 7884806-7912760 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043368, HPA076524" Supported Approved "Nucleoplasm,Nucleoli,Centriolar satellite" "Nucleoplasm, Nucleoli, Centriolar satellite" "HPA043368: , HPA076524: " "unprognostic (1.77e-2)" "unprognostic (8.01e-2)" "prognostic unfavourable (2.43e-4)" "prognostic favourable (7.68e-5)" "unprognostic (1.53e-1)" "unprognostic (8.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.11e-1)" "unprognostic (2.83e-2)" "unprognostic (5.25e-3)" "prognostic favourable (8.36e-4)" "unprognostic (9.11e-2)" "unprognostic (8.31e-2)" "unprognostic (3.98e-2)" "unprognostic (1.50e-1)" "unprognostic (8.90e-3)" "unprognostic (2.20e-3)" 10.4 12.9 31.7 24.3 26.0 18.7 12.5 12.1 28.3 41.1 21.1 4.1 22.5 8.2 46.3 16.1 15.1 25.0 20.0 8.7 30.4 14.2 15.2 2.3 13.1 19.0 8.4 28.4 27.3 15.1 28.5 21.0 8.0 10.7 32.9 11.1 20.7 19.4 23.0 3.3 16.2 14.0 23.3 6.9 14.6 15.8 11.3 5.1 40.6 19.7 7.5 17.7 20.6 28.9 1.6 4.0 4.1 3.5 2.7 7.8 3.6 12.1 30.4 17.8 23.6 21.7 18.2 9.5 14.2 19.1 12.1 12.9 5.9 10.3 34.3 10.8 20.9 16.5 33.4 15.0 15.2 17.4 19.4 16.6 39.4 0.7 11.6 4.7 32.7 24.0 8.0 16.2 10.9 22.3 11.1 0.5 11.2 12.0 13.1 5.5 2.8 11.2 38.4 21.7 5.2 12.0 29.7 12.1 16.4 35.3 13.8 6.9 15.8 7.8 27.9 26.2 20.6 6.3 20.4 2.5 0.4 19.4 13.3 13.5 22.3 0.6 2.7 4.1 7.0 1.7 5.5 1.5 6.7 6.6 2.1 1.6 7.8 5.1 2.1 2.7 3.5 4.0 3.6 3.6 31.7 26.0 12.1 28.3 30.4 14.2 8.4 28.4 10.7 5.1 CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012008 Supported Enhanced Nucleoplasm Nucleoplasm "HPA012008: AB_1846633" "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.71e-2)" "unprognostic (6.40e-3)" "unprognostic (8.99e-2)" "unprognostic (3.36e-3)" "prognostic unfavourable (6.03e-6)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (9.84e-2)" "unprognostic (1.66e-1)" 23.5 34.9 21.9 50.0 33.5 27.2 25.9 29.4 25.1 28.1 29.5 29.3 38.5 18.6 37.2 35.4 29.1 28.0 40.3 52.8 23.5 19.2 29.5 25.0 25.5 30.9 33.6 19.4 34.6 27.4 58.4 25.3 29.5 27.2 21.5 26.0 26.5 24.8 46.2 33.7 31.1 24.4 36.6 30.3 29.4 27.2 29.7 28.9 75.7 38.4 33.7 38.4 34.7 24.3 12.6 16.8 12.8 9.1 13.5 16.7 5.8 20.5 18.7 46.5 17.4 19.1 21.5 27.3 22.8 22.2 25.2 23.2 31.2 16.0 44.2 9.1 25.7 18.4 43.6 25.1 34.0 33.0 22.4 61.7 29.1 19.5 16.6 48.4 29.6 20.7 12.5 24.3 17.1 29.3 48.5 22.1 23.9 25.7 45.9 15.8 44.5 17.7 39.4 28.6 24.1 15.9 24.3 22.0 28.3 29.3 32.6 22.6 14.9 27.6 27.2 25.7 54.8 18.8 26.6 35.8 21.3 56.4 17.0 29.6 18.8 9.0 7.7 9.2 12.2 9.1 12.0 10.5 10.3 11.1 7.9 12.6 13.0 12.3 12.8 13.5 8.1 16.8 16.7 5.8 21.9 33.5 29.4 25.1 23.5 19.2 33.6 19.4 27.2 28.9 CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101793-6180123 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.4;pituitary gland: 22.3;testis: 16.4" "Group enriched" "Detected in some" 4 "SCLC-21H: 16.6;U-2 OS: 7.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" 1.1 7.9 19.8 1.3 17.1 1.0 1.0 12.1 41.4 1.2 1.4 0.7 0.0 1.3 1.2 1.2 1.5 1.2 1.2 1.6 15.3 10.1 1.3 1.0 1.2 1.0 4.3 19.1 1.1 1.4 1.3 22.3 1.0 8.0 1.9 1.3 2.3 1.2 4.8 1.2 1.0 1.4 1.2 1.6 1.1 1.2 16.4 0.8 0.0 1.0 0.0 1.0 1.1 0.4 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.1 0.1 0.0 0.0 0.1 0.2 2.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.3 1.5 0.0 0.3 1.3 0.0 0.0 0.0 0.0 16.6 0.2 0.1 0.0 0.0 2.8 0.1 0.0 0.1 7.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 19.8 17.1 12.1 34.2 15.3 10.1 4.3 19.1 8.0 0.8 CHD6 "CHD5, dJ620E11.1, FLJ22369, KIAA1335, RIGB" ENSG00000124177 "Chromodomain helicase DNA binding protein 6" Q8TD26 20 41402101-41618494 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015543 Approved Nucleoplasm Nucleoplasm "HPA015543: " "unprognostic (5.13e-3)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.27e-1)" "unprognostic (6.66e-2)" "unprognostic (1.36e-1)" "unprognostic (4.72e-3)" "prognostic favourable (3.42e-4)" "unprognostic (1.17e-1)" "unprognostic (3.17e-1)" "unprognostic (4.75e-2)" "unprognostic (1.14e-1)" "unprognostic (2.12e-3)" "unprognostic (6.66e-2)" "unprognostic (3.41e-1)" "unprognostic (1.00e-1)" "unprognostic (1.14e-2)" 12.1 12.6 16.5 12.7 16.2 18.1 19.4 34.1 24.9 17.4 11.3 16.6 15.4 6.5 20.4 19.9 11.0 16.3 11.7 12.1 15.8 13.9 11.8 10.7 11.7 12.1 14.7 16.8 26.1 12.5 31.4 30.3 12.9 24.3 19.7 10.0 14.2 14.5 17.0 9.4 14.4 10.5 14.4 17.3 12.0 12.3 11.1 18.2 21.4 21.4 6.7 15.3 16.9 15.0 12.0 11.5 15.1 9.3 10.4 10.4 2.3 6.4 7.6 16.4 7.2 9.3 9.6 10.9 5.6 11.6 10.0 12.3 10.4 5.3 7.7 10.2 9.5 9.5 10.2 9.6 11.5 2.4 4.9 10.5 6.9 10.0 5.2 8.2 5.2 9.6 9.0 7.3 8.1 8.6 8.2 8.7 7.7 17.6 12.9 8.9 5.3 12.7 10.0 19.4 5.4 6.2 14.8 14.8 10.2 17.1 4.6 11.4 7.8 6.2 9.9 15.8 7.8 8.4 4.8 7.9 6.3 9.9 7.1 4.0 4.9 15.1 6.5 7.1 8.9 6.2 8.9 8.8 7.7 7.3 5.1 12.0 10.4 8.7 0.9 10.4 9.3 11.5 5.9 2.3 16.5 16.2 34.1 24.9 15.8 13.9 14.7 16.8 24.3 18.2 CHD7 "CRG, FLJ20357, FLJ20361, KIAA1416" ENSG00000171316 "Chromodomain helicase DNA binding protein 7" Q9P2D1 8 60678778-60868028 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.1" "Cell line enhanced" "Detected in many" "AF22: 25.8;SCLC-21H: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 15 "B-cells: 12.2;granulocytes: 12.6;T-cells: 5.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebellum: 110.3" HPA053075 Supported Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA053075: " "unprognostic (3.77e-2)" "unprognostic (3.28e-3)" "unprognostic (3.17e-2)" "prognostic unfavourable (5.34e-5)" "unprognostic (9.59e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-3)" "unprognostic (3.41e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (9.09e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-1)" "unprognostic (8.20e-2)" "unprognostic (2.17e-1)" 3.9 2.2 7.0 7.9 11.2 25.1 4.1 47.1 9.0 2.3 5.7 13.4 3.1 5.9 2.6 3.2 5.1 3.2 3.1 4.1 8.1 4.3 3.6 3.6 4.7 7.0 8.1 3.3 1.4 6.4 12.4 9.9 5.6 9.9 2.9 5.5 6.4 5.7 2.8 10.3 5.7 6.6 2.4 7.5 6.1 4.5 4.3 12.2 1.6 5.4 2.2 7.3 2.9 5.9 12.2 0.6 12.6 0.6 0.0 5.5 0.4 3.8 1.9 25.8 4.5 0.0 0.0 8.1 0.2 0.0 0.9 0.8 4.8 3.6 7.5 0.4 0.0 2.3 13.2 3.8 0.8 2.8 7.1 17.6 3.2 6.3 1.1 5.3 3.3 0.5 2.9 0.0 4.3 3.8 1.3 6.7 0.6 3.9 8.3 6.0 17.7 0.9 17.3 6.1 2.4 2.0 4.4 23.6 11.7 0.7 2.9 7.2 5.2 5.0 4.4 0.2 4.2 0.2 2.1 7.1 4.1 11.7 1.5 0.6 6.6 10.4 0.3 12.6 2.6 0.1 3.3 8.0 2.9 0.9 0.1 12.2 5.5 2.0 7.1 0.0 0.6 0.6 0.2 0.4 7.0 11.2 47.1 6.5 8.1 4.3 8.1 3.3 9.9 12.2 CHD8 "DUPLIN, HELSNF1, KIAA1564" ENSG00000100888 "Chromodomain helicase DNA binding protein 8" Q9HCK8 14 21385194-21456126 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052186, HPA076133" Enhanced "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA052186: , HPA076133: " "unprognostic (3.45e-1)" "unprognostic (9.71e-2)" "unprognostic (3.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "unprognostic (3.43e-1)" "prognostic unfavourable (4.94e-4)" "unprognostic (7.31e-2)" "unprognostic (9.22e-2)" "prognostic favourable (8.35e-4)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (2.54e-3)" "unprognostic (2.88e-1)" "unprognostic (9.24e-2)" "unprognostic (2.51e-1)" "unprognostic (8.07e-3)" 13.9 14.5 13.0 14.8 21.5 34.8 17.0 28.9 25.7 15.8 14.4 26.6 14.1 11.1 18.3 13.4 17.4 15.9 11.7 12.3 13.5 13.3 14.0 11.2 15.5 18.5 15.4 15.2 20.7 19.0 34.7 25.3 15.2 20.3 16.3 14.6 19.3 15.7 14.9 16.9 24.5 16.4 17.2 13.1 19.2 16.1 15.2 18.1 29.9 17.4 10.4 24.8 16.6 14.5 12.3 7.8 12.8 7.4 8.7 8.6 3.0 16.2 21.3 23.6 11.0 15.1 13.1 13.4 12.9 14.9 19.7 19.7 18.5 14.1 26.9 8.2 17.3 20.0 28.9 18.2 25.0 20.6 13.2 23.6 14.3 22.4 14.0 32.6 22.5 17.6 14.8 22.1 15.9 17.5 16.4 14.4 14.9 17.5 23.4 13.3 18.0 18.1 22.0 17.9 9.1 14.6 30.1 17.3 16.6 20.3 15.8 11.2 11.1 15.8 20.5 16.4 12.6 9.6 15.3 16.4 19.5 26.9 6.6 12.1 16.3 12.8 4.8 12.1 7.7 5.0 8.6 5.8 6.8 7.5 3.3 12.3 7.4 6.4 11.0 8.7 7.4 7.8 5.7 3.0 13.0 21.5 28.9 25.7 13.5 13.3 15.4 15.2 20.3 18.1 CHD9 "BC022889, FLJ12178, KIAA0308" ENSG00000177200 "Chromodomain helicase DNA binding protein 9" Q3L8U1 16 53055033-53329150 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 42.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042053, HPA049420" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA042053: , HPA049420: " "unprognostic (3.57e-2)" "unprognostic (3.73e-2)" "unprognostic (3.44e-3)" "unprognostic (2.42e-1)" "unprognostic (4.34e-2)" "unprognostic (4.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "unprognostic (7.75e-3)" "unprognostic (2.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.35e-2)" "prognostic favourable (1.84e-4)" "unprognostic (4.96e-2)" "unprognostic (1.74e-1)" "unprognostic (5.09e-2)" "unprognostic (2.87e-1)" 18.0 12.6 14.5 12.5 17.3 30.3 15.7 49.3 19.6 18.5 13.8 6.6 17.4 8.0 14.2 15.0 14.4 13.5 11.6 12.2 15.9 8.2 16.8 12.3 12.3 9.2 16.0 12.3 18.8 12.9 28.1 39.9 12.3 15.1 13.7 11.5 8.9 17.8 15.3 17.1 14.4 11.1 11.6 20.1 11.6 13.4 7.0 18.7 15.6 17.7 11.2 9.4 13.9 15.1 16.4 42.9 23.7 12.7 12.1 8.8 1.7 5.7 6.7 15.0 12.2 11.2 16.4 2.6 10.6 7.8 5.6 2.5 3.7 5.2 7.7 6.9 8.7 7.0 7.8 5.5 7.9 2.7 5.8 10.9 6.4 2.3 7.8 15.1 9.1 11.3 5.6 8.2 10.4 8.3 12.7 2.6 7.0 2.2 7.5 3.4 5.4 5.1 26.5 18.0 3.3 3.4 5.4 6.4 7.1 9.4 3.1 7.8 3.4 7.0 16.0 10.6 5.4 3.9 7.1 8.0 5.5 13.5 7.5 6.5 10.4 23.7 9.2 8.9 5.7 7.6 8.8 12.5 3.9 6.2 5.4 16.4 3.1 4.4 3.0 12.1 12.7 42.9 1.9 1.7 14.5 17.3 49.3 19.6 15.9 8.2 16.0 12.3 15.1 18.7 CHDH ENSG00000016391 "Choline dehydrogenase" Q8NE62 3 53812335-53846390 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 36.6;liver: 24.0" "Cell line enhanced" "Detected in some" "CACO-2: 8.4;Hep G2: 25.8;T-47d: 8.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 6.4;T-reg: 2.8" "Group enriched" "Detected in many" 15 "granulocytes: 6.4;T-cells: 2.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036633, HPA058130" Enhanced "HPA036633: AB_10670841, HPA058130: " "unprognostic (3.40e-3)" "unprognostic (1.17e-2)" "unprognostic (2.26e-3)" "unprognostic (7.17e-3)" "unprognostic (9.15e-2)" "unprognostic (1.17e-3)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (2.75e-1)" "unprognostic (4.35e-3)" "unprognostic (4.57e-2)" "unprognostic (5.12e-2)" "prognostic favourable (1.88e-8)" "unprognostic (3.37e-2)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (2.29e-2)" 0.7 2.2 11.6 2.3 9.7 0.9 7.8 12.9 10.2 4.1 8.8 8.2 0.8 8.3 3.2 3.8 1.0 2.8 5.5 3.3 13.8 4.0 36.6 24.0 2.6 1.4 11.9 6.5 1.6 15.5 8.0 5.9 0.8 10.0 5.4 9.4 3.3 13.7 1.5 3.8 1.6 14.0 1.4 6.4 0.7 8.1 4.5 13.0 0.0 4.1 0.1 1.6 0.8 1.0 0.3 0.1 6.4 0.1 0.1 2.8 0.1 0.3 3.4 0.9 0.1 0.0 0.0 3.9 0.2 0.4 0.0 0.0 8.4 0.6 0.3 0.6 0.6 0.0 5.5 0.0 0.0 0.0 3.0 0.0 1.2 25.8 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 4.0 0.5 0.0 5.0 0.0 0.1 5.4 0.6 0.0 1.4 5.9 3.9 3.0 2.3 3.0 1.4 0.1 0.0 8.5 0.1 0.0 0.0 0.6 0.2 0.8 0.8 1.1 0.0 0.0 0.0 0.0 6.4 0.1 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.0 0.2 0.1 0.1 0.5 0.1 0.1 0.1 2.8 0.1 11.6 9.7 12.9 10.2 13.8 4.0 11.9 6.5 10.0 13.0 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625136-125676255 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ductus deferens: 80.0;seminal vesicle: 66.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 11.7" "Lineage enriched" "Detected in many" 6 "T-cells: 11.7" "Low region specificity" "Detected in single" HPA044364 Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA044364: " "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favourable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavourable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavourable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavourable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 3.0 2.5 2.5 9.0 2.8 14.9 2.1 1.1 2.2 2.5 5.2 1.3 80.0 5.0 1.9 10.2 6.5 1.7 3.6 1.5 2.4 2.4 3.7 2.0 1.8 9.6 3.0 1.2 3.8 4.0 25.5 3.5 3.8 1.5 2.9 6.3 1.6 2.6 66.8 1.2 2.9 5.2 2.3 3.0 3.6 2.8 7.2 1.5 22.4 1.8 4.5 8.8 3.8 3.3 1.9 1.8 1.9 0.7 1.2 11.7 1.0 12.7 10.4 23.4 14.2 4.8 10.3 10.2 17.9 8.6 11.5 12.4 25.4 28.3 33.4 18.5 7.0 15.4 14.3 9.4 14.2 20.9 6.6 61.9 8.7 13.0 1.5 31.6 11.8 5.3 2.0 14.5 10.3 13.6 31.3 29.4 15.1 6.6 46.9 15.5 23.7 9.4 28.6 21.9 17.5 10.6 17.0 14.8 15.7 14.7 10.2 4.3 27.5 10.3 9.1 16.6 14.1 8.0 16.4 6.6 11.8 47.6 6.1 23.8 19.4 1.9 0.5 0.3 1.3 0.7 1.2 1.9 3.5 1.6 1.1 1.5 3.3 2.0 0.4 1.2 0.4 1.8 11.7 1.0 2.5 2.8 1.1 2.2 2.4 2.4 3.0 1.2 1.5 1.5 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavourable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 5.6 8.3 2.5 13.0 7.0 13.7 5.6 0.7 5.6 6.6 9.8 2.5 4.8 6.8 4.8 10.9 10.0 4.3 6.0 6.0 4.1 2.3 5.3 6.5 7.9 10.1 6.7 1.6 12.9 6.7 1.2 4.2 10.1 5.1 8.3 10.6 8.7 7.0 5.8 2.2 6.3 8.5 5.4 5.0 9.8 5.8 9.7 3.6 13.1 7.5 4.8 13.7 6.2 6.7 11.8 8.7 6.5 8.4 2.9 4.4 3.7 14.7 4.7 13.5 16.7 3.8 19.2 8.7 7.3 8.6 9.7 14.2 12.0 10.1 17.4 6.2 5.1 14.2 20.5 13.4 11.3 12.4 15.7 22.9 9.0 19.8 3.8 14.5 16.8 8.1 6.2 12.4 11.0 10.7 13.8 15.2 9.0 20.7 11.6 23.3 19.0 12.0 25.3 9.2 20.3 6.0 6.1 7.9 4.5 8.1 14.5 8.0 9.9 13.4 3.7 7.8 9.3 6.8 3.8 9.2 16.2 34.0 7.4 15.2 9.9 6.5 3.7 1.2 1.1 8.4 2.3 11.8 2.2 2.1 8.7 8.4 4.4 2.8 0.3 2.9 4.1 7.0 2.8 3.7 2.5 7.0 0.7 5.6 4.1 2.3 6.7 1.6 5.1 3.6 CHFR "FLJ10796, RNF196" ENSG00000072609 "Checkpoint with forkhead and ring finger domains" Q96EP1 12 132822187-132956304 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045768, HPA073826" Approved Uncertain "Nuclear bodies,Microtubules" "Nuclear bodies, Microtubules" "HPA045768: , HPA073826: " "unprognostic (1.46e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (3.86e-2)" "unprognostic (2.08e-1)" "unprognostic (2.14e-3)" "unprognostic (6.56e-4)" "unprognostic (1.94e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.00e-2)" "unprognostic (3.98e-3)" "prognostic unfavourable (4.21e-9)" "unprognostic (5.03e-1)" "unprognostic (8.46e-2)" "unprognostic (6.71e-2)" "unprognostic (1.11e-2)" 13.7 11.4 14.1 19.0 15.0 25.8 12.5 20.0 16.9 12.1 15.2 16.5 13.4 19.0 15.6 16.7 21.6 12.6 14.3 13.7 12.5 9.8 12.8 13.4 17.0 21.7 15.1 12.6 9.6 16.8 9.6 20.6 22.9 13.0 14.3 12.8 15.5 13.9 14.7 21.0 16.7 18.7 17.8 15.1 24.9 16.8 19.2 14.2 22.3 13.5 12.7 18.4 18.6 14.2 6.6 12.1 19.7 17.0 12.3 12.5 10.1 4.4 10.8 9.1 0.8 8.0 10.7 17.0 9.1 7.6 9.7 10.1 8.5 3.8 0.1 8.8 10.6 7.1 1.1 9.2 5.6 0.6 9.6 14.4 7.4 8.6 17.5 0.6 25.0 14.4 8.4 8.8 6.6 11.8 6.1 0.0 6.7 14.8 10.4 11.2 10.9 8.6 1.4 1.3 4.4 6.4 20.9 8.9 11.4 7.5 7.7 7.0 13.8 14.9 13.2 0.6 2.2 5.0 3.3 15.9 0.0 2.1 0.0 3.0 8.7 17.6 14.2 19.7 10.8 16.9 10.0 6.6 8.7 11.6 12.1 4.5 8.3 9.1 18.9 12.3 17.0 6.6 12.5 10.1 14.1 15.0 20.0 16.9 12.5 9.8 15.1 12.6 13.0 14.2 CHIA "AMCase, CHIT2, TSA1902" ENSG00000134216 "Chitinase, acidic" Q9BZP6 1 111290862-111320566 "Enzymes, Predicted intracellular proteins" "Apoptosis, Carbohydrate metabolism, Chitin degradation, Immunity, Inflammatory response, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 66.6" "Group enriched" "Detected in some" 4 "ASC diff: 5.9;HAP1: 3.1" "Cancer enhanced" "Detected in some" "lung cancer: 1.8;stomach cancer: 2.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.6" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" HPA059193 Approved "Intracellular and membrane" "HPA059193: " "unprognostic (8.00e-2)" "unprognostic (7.08e-2)" "unprognostic (2.02e-2)" "unprognostic (4.99e-2)" "unprognostic (7.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.7 0.5 0.8 0.3 0.1 0.1 0.1 0.0 0.5 1.0 13.2 0.2 0.1 0.1 0.1 0.1 0.6 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.1 0.1 66.6 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 1.6 0.7 0.0 0.1 0.6 0.6 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.7 0.2 0.2 0.0 1.6 0.6 0.0 0.0 0.6 0.0 0.7 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CHIT1 "CHI3, CHIT" ENSG00000133063 "Chitinase 1" Q13231 1 203212827-203273641 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 99.9;lymphoid tissue: 106.5" "Cell line enhanced" "Detected in some" "EFO-21: 2.7;LHCN-M2: 1.7;RH-30: 1.7;U-266/70: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 31.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 2.9;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 4 "granulocytes: 2.9;monocytes: 1.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA010575, HPA074844" Supported "Secreted to blood" 26410000 58000000 "HPA010575: AB_1078512, HPA074844: " "unprognostic (5.80e-3)" "prognostic favourable (2.02e-4)" "unprognostic (2.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.55e-2)" "unprognostic (6.36e-3)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-3)" "unprognostic (3.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" 99.9 0.2 0.2 0.4 0.3 26.7 5.5 0.1 0.3 5.9 0.6 0.5 0.1 0.0 2.5 0.2 0.3 0.1 0.2 0.6 0.2 0.1 0.1 0.4 22.1 106.5 0.4 0.1 1.4 1.1 0.0 0.2 0.4 0.5 0.6 0.5 0.3 0.3 0.1 0.1 0.3 0.7 0.2 9.4 4.3 0.1 0.1 0.1 2.3 0.9 0.2 0.5 0.1 0.3 0.5 0.2 2.9 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 2.7 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.7 0.2 0.0 0.0 0.1 0.2 0.0 1.7 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 2.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.9 0.0 1.1 0.2 0.0 1.3 0.2 0.3 0.1 0.3 0.2 0.1 0.4 0.1 0.5 0.1 CHKA "CHK, CKI" ENSG00000110721 "Choline kinase alpha" P35790 11 68052859-68121444 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 9.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024153, CAB072803" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB072803: , HPA024153: AB_1846664" "unprognostic (5.16e-2)" "unprognostic (1.46e-1)" "unprognostic (2.52e-1)" "unprognostic (2.51e-1)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "prognostic unfavourable (7.75e-4)" "unprognostic (2.36e-3)" "unprognostic (1.66e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (5.97e-3)" "unprognostic (5.00e-2)" "unprognostic (6.06e-2)" "unprognostic (1.82e-1)" "unprognostic (4.73e-2)" 8.9 15.5 18.1 6.4 19.5 25.5 18.6 10.2 19.3 10.8 18.2 30.9 28.8 19.0 5.8 19.2 3.9 6.5 10.7 5.4 18.7 15.4 8.0 17.4 11.4 7.5 26.5 12.5 10.4 29.3 9.2 10.0 5.0 21.5 13.5 11.8 17.4 36.9 37.4 3.9 4.2 22.8 8.2 20.9 13.5 18.8 55.9 22.7 3.1 19.9 2.2 5.2 8.7 4.7 1.3 1.5 9.5 2.5 1.6 0.7 0.4 7.9 7.0 8.1 7.8 2.8 1.9 8.3 2.6 4.2 7.2 4.7 29.9 22.7 6.2 9.5 3.7 5.3 11.4 1.8 5.5 2.8 4.0 7.6 9.1 34.6 7.9 8.1 4.2 3.8 3.1 3.3 1.6 4.0 7.2 10.7 3.8 6.2 4.3 22.0 13.2 4.7 6.9 8.6 17.3 6.0 9.0 6.0 6.4 4.9 24.9 57.4 10.6 11.1 2.3 4.5 5.7 10.9 3.3 12.6 12.9 10.8 5.0 10.6 4.2 0.0 1.4 9.5 0.2 2.5 0.0 1.3 0.1 0.4 1.5 0.6 0.7 0.5 0.8 1.6 1.5 1.2 0.3 0.4 18.1 19.5 10.2 19.3 18.7 15.4 26.5 12.5 21.5 22.7 CHKB "CHETK, CHKL" ENSG00000100288 "Choline kinase beta" Q9Y259 22 50578949-50601455 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Congenital muscular dystrophy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA018797 Approved Approved Cytosol Cytosol "HPA018797: AB_1846666" "unprognostic (6.03e-4)" "prognostic favourable (4.66e-4)" "unprognostic (4.31e-2)" "unprognostic (2.63e-2)" "unprognostic (2.14e-1)" "unprognostic (1.42e-2)" "unprognostic (3.25e-3)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (7.84e-2)" "unprognostic (5.23e-3)" "unprognostic (5.43e-2)" "prognostic unfavourable (1.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.54e-2)" "unprognostic (1.30e-2)" "unprognostic (2.18e-3)" 14.1 13.6 12.7 18.9 14.4 14.8 13.0 21.3 13.4 12.9 15.1 13.8 10.4 9.8 10.1 12.5 10.7 16.2 13.6 10.6 10.7 6.8 14.3 9.3 12.6 8.7 14.7 6.1 9.1 8.4 21.9 19.2 12.3 12.7 11.7 6.9 12.8 13.4 12.5 7.8 10.5 16.9 8.0 9.5 18.5 14.8 19.9 15.8 8.5 14.5 6.6 16.5 12.1 10.9 13.6 21.2 15.0 23.9 20.6 18.6 19.5 3.6 1.0 3.0 1.1 3.1 2.1 10.1 4.3 8.6 1.8 2.4 0.0 1.4 1.8 3.3 0.0 1.7 1.5 0.9 0.3 1.5 4.3 2.4 2.2 0.8 14.4 2.9 6.1 0.9 5.3 0.7 3.6 9.0 1.2 4.7 4.8 3.3 2.6 8.2 0.5 0.6 3.3 0.4 10.1 3.9 2.5 1.4 4.2 3.4 3.4 3.0 1.2 1.8 2.7 1.7 3.6 1.6 1.2 7.7 0.7 2.3 2.9 2.2 1.7 5.7 23.9 15.0 16.3 21.9 15.5 12.9 15.2 17.3 21.2 13.6 14.4 13.3 5.7 20.6 14.2 19.5 18.6 19.5 12.7 14.4 21.3 13.4 10.7 6.8 14.7 6.1 12.7 15.8 CHPF "CHSY2, CSS2" ENSG00000123989 "Chondroitin polymerizing factor" Q8IZ52 2 219538947-219543787 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 11.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035123 Approved Supported Vesicles,Centrosome,Cytosol "Intracellular and membrane" Cytosol "Vesicles, Centrosome" "HPA035123: AB_10602799" "unprognostic (1.13e-3)" "prognostic unfavourable (1.57e-4)" "unprognostic (3.65e-3)" "unprognostic (2.55e-3)" "unprognostic (1.86e-3)" "prognostic unfavourable (1.68e-4)" "unprognostic (1.37e-1)" "unprognostic (6.59e-3)" "unprognostic (7.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (6.79e-2)" "unprognostic (1.64e-1)" "unprognostic (6.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "prognostic unfavourable (2.96e-4)" 8.6 14.1 9.7 8.4 11.8 1.4 6.8 8.5 19.4 22.1 8.6 11.3 23.0 18.4 17.0 24.6 7.9 9.2 17.1 36.3 12.2 10.7 11.3 52.1 11.6 5.4 9.0 10.5 38.1 60.7 16.3 36.9 62.7 10.4 19.3 3.8 27.4 31.6 19.9 4.3 9.0 13.3 9.1 8.3 4.5 15.6 34.2 7.0 3.8 17.9 7.4 10.6 11.9 8.5 1.3 11.1 6.9 0.1 2.1 3.0 0.8 18.5 3.7 2.7 23.2 10.6 16.6 31.8 18.9 16.0 5.4 4.9 10.3 16.4 5.8 40.7 18.2 23.8 1.8 11.4 0.8 8.9 6.4 2.0 5.2 44.5 14.8 1.8 12.2 22.3 20.1 5.4 5.2 0.0 12.9 14.2 5.1 29.2 0.2 4.8 11.5 14.3 0.0 8.8 11.3 6.4 8.4 6.8 10.4 9.1 8.8 25.8 3.0 6.3 0.4 19.9 10.9 23.7 9.8 17.1 5.3 2.6 18.2 1.8 20.0 2.1 0.0 6.9 2.4 0.1 3.0 1.3 1.9 1.6 0.0 0.1 2.2 0.8 0.0 2.1 0.0 11.1 1.2 0.8 9.7 11.8 8.5 19.4 12.2 10.7 9.0 10.5 10.4 7.0 CHPF2 "ChSy-3, CSGlcA-T, KIAA1402" ENSG00000033100 "Chondroitin polymerizing factor 2" Q9P2E5 7 151232489-151238827 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020992 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" "Nucleoplasm, Cytosol" "HPA020992: AB_1847267" "unprognostic (8.31e-2)" "unprognostic (2.14e-3)" "unprognostic (1.02e-3)" "unprognostic (1.14e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "prognostic unfavourable (9.47e-4)" "unprognostic (4.07e-1)" "unprognostic (1.71e-1)" "unprognostic (4.54e-2)" "prognostic favourable (2.51e-4)" "unprognostic (1.04e-1)" "unprognostic (2.68e-3)" "unprognostic (2.24e-1)" "unprognostic (1.49e-1)" "unprognostic (3.22e-2)" "unprognostic (8.59e-3)" 13.5 29.3 13.4 19.0 12.9 22.6 19.1 13.1 20.2 15.3 14.4 11.4 20.7 14.9 19.5 16.9 13.3 14.9 17.6 18.8 13.7 12.5 14.9 20.7 17.4 23.4 11.4 17.4 14.4 23.7 16.7 41.5 18.6 11.8 18.5 10.8 12.2 25.4 19.8 7.9 14.2 17.1 17.3 9.4 28.1 20.1 12.9 11.1 16.2 17.5 7.4 13.7 18.9 12.8 2.7 9.5 9.9 5.6 2.6 5.7 3.7 8.9 7.3 4.9 14.4 17.2 17.1 7.5 18.9 29.6 10.3 12.6 4.8 15.3 2.7 33.5 30.0 11.3 2.2 13.5 4.5 10.3 6.7 2.8 8.0 6.7 16.2 5.8 24.0 26.2 7.6 9.7 3.5 16.2 2.7 7.9 16.3 14.7 5.4 22.7 6.6 8.5 5.1 2.9 9.0 10.0 7.1 5.4 9.5 10.1 10.0 4.8 3.8 9.6 22.0 11.5 1.9 15.2 16.0 14.6 2.1 3.9 41.7 7.8 15.5 1.2 5.6 7.9 5.7 5.1 5.4 2.7 3.1 5.1 6.3 2.7 2.2 2.3 9.9 2.6 5.0 9.5 3.4 3.7 13.4 12.9 13.1 20.2 13.7 12.5 11.4 17.4 11.8 11.1 CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 19.4;eosinophil: 9.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles Vesicles "HPA067643: " "unprognostic (1.59e-3)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.48e-2)" "unprognostic (3.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.79e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.70e-1)" "unprognostic (5.27e-2)" "unprognostic (1.16e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.72e-1)" "prognostic favourable (7.41e-4)" "unprognostic (1.79e-1)" 18.0 21.6 19.3 14.3 20.4 21.4 76.7 12.8 16.7 22.2 40.0 11.0 15.8 36.5 9.3 25.0 10.9 14.7 17.1 71.4 18.5 14.5 30.6 64.6 20.2 30.5 17.8 14.5 11.3 14.2 12.6 7.6 9.6 12.8 16.3 21.0 14.0 53.1 22.8 18.5 13.5 42.9 16.7 17.4 13.0 23.1 28.3 12.6 3.3 26.0 7.4 8.7 17.7 38.7 3.0 2.5 19.4 1.5 3.3 0.8 0.4 3.4 16.3 4.4 9.4 35.2 11.8 12.6 12.7 14.6 12.8 8.3 6.0 2.4 5.3 7.2 17.2 5.3 26.6 4.4 12.2 8.0 22.5 21.6 8.7 35.0 19.7 10.6 4.4 11.1 1.3 5.7 10.6 6.3 31.3 13.8 12.5 8.5 6.3 36.8 11.7 21.6 4.9 8.6 3.8 5.8 13.7 4.3 3.3 11.7 16.9 31.5 17.2 7.3 4.6 11.7 6.1 9.1 12.3 7.9 2.4 6.5 9.2 12.4 17.0 19.4 1.5 9.7 0.4 1.2 0.4 3.0 0.8 0.7 2.0 2.0 0.3 0.4 2.2 3.3 1.4 2.5 0.4 0.4 19.3 20.4 12.8 16.7 18.5 14.5 17.8 14.5 12.8 12.6 CHST11 "C4ST, C4St-1, C4ST1, HSA269537" ENSG00000171310 "Carbohydrate sulfotransferase 11" Q9NPF2 12 104455295-104762014 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052828 Approved Approved "Golgi apparatus" "Intracellular and membrane" 22000 "Golgi apparatus" "HPA052828: " "unprognostic (6.35e-2)" "unprognostic (2.68e-3)" "unprognostic (2.28e-2)" "unprognostic (7.53e-2)" "unprognostic (3.45e-2)" "unprognostic (2.64e-2)" "unprognostic (1.64e-3)" "unprognostic (9.21e-3)" "unprognostic (3.12e-1)" "unprognostic (9.02e-2)" "unprognostic (1.22e-2)" "unprognostic (5.44e-2)" "prognostic unfavourable (7.59e-11)" "unprognostic (1.64e-2)" "unprognostic (5.60e-2)" "unprognostic (5.40e-3)" "prognostic unfavourable (8.42e-4)" 6.7 14.3 14.6 21.6 16.6 37.3 4.9 5.7 16.1 6.6 6.2 8.2 9.7 3.9 15.7 16.1 4.4 5.2 11.1 6.6 13.4 11.9 4.4 4.0 15.3 22.5 11.5 6.7 8.7 6.3 1.9 6.8 17.2 10.0 6.4 5.2 16.1 3.3 13.4 1.7 2.7 7.7 12.6 10.5 17.5 8.3 3.3 11.8 26.5 4.3 2.9 15.6 8.5 5.3 2.0 2.6 13.8 1.3 1.3 2.8 0.6 13.5 6.3 2.9 1.8 7.4 3.6 10.3 1.3 0.4 0.6 0.5 0.0 17.8 0.0 2.0 1.8 3.4 1.7 7.1 0.7 0.1 2.5 18.1 1.6 0.0 1.1 21.0 21.5 1.3 1.0 11.6 1.9 4.5 27.9 4.6 1.2 3.3 16.1 24.9 2.4 2.3 18.3 9.7 4.5 6.0 0.1 4.9 8.0 0.8 9.2 17.1 2.7 21.4 10.4 2.0 2.2 10.4 11.2 24.1 25.9 3.4 9.4 14.8 20.2 9.3 1.3 9.4 2.8 1.2 1.6 0.9 1.5 2.1 0.7 2.0 0.7 1.8 13.8 1.3 1.1 2.6 2.8 0.6 14.6 16.6 5.7 10.4 13.4 11.9 11.5 6.7 10.0 11.8 CHST12 "C4S-2, C4ST2" ENSG00000136213 "Carbohydrate sulfotransferase 12" Q9NRB3 7 2403560-2448483 "Enzymes, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 25.6;NB-4: 26.5;U-266/70: 37.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041680 Approved Approved "Golgi apparatus" 430000 "Golgi apparatus" "HPA041680: AB_10959789" "unprognostic (4.12e-2)" "unprognostic (3.56e-1)" "unprognostic (3.04e-3)" "unprognostic (1.59e-1)" "unprognostic (2.05e-3)" "unprognostic (7.15e-2)" "unprognostic (2.01e-3)" "unprognostic (1.34e-1)" "unprognostic (3.20e-2)" "unprognostic (4.88e-2)" "prognostic favourable (1.32e-5)" "unprognostic (9.61e-2)" "unprognostic (1.66e-3)" "unprognostic (4.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" 24.2 12.0 9.4 12.1 10.5 14.5 11.2 17.8 16.5 11.9 10.1 13.2 9.0 13.5 14.4 10.6 5.9 11.7 10.9 12.0 8.8 7.7 9.3 6.8 13.6 10.3 10.4 9.2 9.6 17.5 4.9 14.4 9.6 12.7 11.8 4.2 12.3 14.1 11.6 11.9 11.5 10.1 8.1 9.5 25.0 12.4 10.2 8.6 9.0 11.2 4.4 11.8 10.6 10.3 5.7 21.0 16.4 3.5 37.4 30.2 6.7 3.8 4.0 2.4 4.4 3.7 2.7 12.5 7.0 3.3 3.1 4.2 4.4 1.5 3.4 13.4 3.1 3.2 1.5 1.9 0.8 4.5 8.3 2.3 3.4 4.9 1.7 7.8 25.6 3.6 1.1 2.7 0.3 3.2 6.1 12.4 1.4 3.6 8.2 26.5 8.4 7.2 3.1 3.2 17.9 1.5 2.1 3.0 12.2 3.4 2.6 1.7 3.2 10.0 5.3 4.5 11.8 8.8 6.2 37.9 14.6 1.5 3.6 4.0 7.8 15.5 3.5 16.4 30.2 2.8 18.9 5.2 10.7 24.5 6.6 5.7 4.5 13.5 1.0 37.4 1.2 21.0 10.2 6.7 9.4 10.5 17.8 16.5 8.8 7.7 10.4 9.2 12.7 8.6 CHST14 "D4ST-1, D4ST1, HD4ST" ENSG00000169105 "Carbohydrate sulfotransferase 14" Q8NCH0 15 40470998-40474571 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease mutation, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057697, HPA071601" Enhanced Approved Vesicles Vesicles "HPA057697: , HPA071601: " "unprognostic (5.46e-2)" "unprognostic (9.23e-2)" "unprognostic (4.03e-2)" "unprognostic (2.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-2)" "unprognostic (6.94e-2)" "unprognostic (1.70e-1)" "unprognostic (9.95e-2)" "unprognostic (2.84e-1)" "unprognostic (3.17e-2)" "unprognostic (5.85e-3)" "unprognostic (2.01e-3)" "unprognostic (1.94e-1)" "unprognostic (6.34e-2)" "unprognostic (2.25e-2)" 10.3 7.9 7.1 7.5 6.9 2.3 22.7 6.5 7.4 14.9 7.9 6.0 13.8 3.6 17.5 11.1 6.5 12.3 14.1 12.6 5.5 2.9 8.1 9.6 15.9 20.9 8.1 4.5 18.8 11.6 10.2 11.4 22.4 7.1 10.7 3.8 9.8 12.7 17.2 5.5 6.8 7.1 13.3 5.9 10.5 7.3 9.2 6.3 7.5 12.4 8.3 6.1 12.1 18.2 2.1 3.4 8.0 1.9 5.5 4.0 1.1 11.0 7.3 11.7 31.6 18.4 14.3 18.3 10.9 20.8 19.4 18.4 8.8 5.6 1.8 16.7 18.5 19.1 10.4 6.1 9.1 13.2 6.1 5.7 7.8 8.4 10.0 2.4 14.8 17.4 5.1 6.8 5.2 17.0 5.5 6.6 14.4 8.4 4.0 12.7 7.5 8.5 11.1 14.9 3.2 13.0 5.7 8.5 13.0 9.6 10.8 3.6 15.7 10.2 13.8 32.9 12.2 10.3 10.8 13.4 9.2 5.1 14.8 8.4 23.6 8.0 1.9 3.6 4.0 1.9 1.1 0.5 2.0 3.4 3.4 2.1 1.8 1.4 0.3 5.5 0.9 1.2 1.3 1.1 7.1 6.9 6.5 7.4 5.5 2.9 8.1 4.5 7.1 6.3 CHST15 "BRAG, GALNAC4S-6ST, KIAA0598" ENSG00000182022 "Carbohydrate sulfotransferase 15" Q7LFX5 10 124007666-124093607 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 27.1;REH: 35.6;U-266/70: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 29.4" "Group enriched" "Detected in many" 10 "granulocytes: 29.4;monocytes: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017584 Approved Approved Centrosome,Cytosol 560000 Cytosol Centrosome "HPA017584: AB_1849437" "unprognostic (1.19e-1)" "unprognostic (2.29e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-2)" "unprognostic (4.12e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (3.02e-2)" "unprognostic (2.40e-2)" "unprognostic (7.62e-3)" "unprognostic (7.90e-2)" "unprognostic (8.16e-2)" "prognostic unfavourable (2.22e-7)" "unprognostic (6.47e-3)" "unprognostic (7.80e-2)" "unprognostic (4.63e-3)" "unprognostic (5.26e-3)" 16.4 10.0 8.7 17.0 20.6 5.7 10.7 3.4 17.9 9.8 15.4 6.6 4.0 8.8 8.6 10.8 11.3 13.1 11.7 6.4 11.3 5.3 9.0 11.9 13.9 35.4 6.5 9.6 35.0 12.6 2.9 7.7 5.9 9.2 8.5 8.3 14.4 8.2 13.4 11.0 8.3 12.5 9.5 9.0 31.5 11.4 4.8 8.7 2.8 19.3 6.1 12.6 12.5 12.0 2.1 2.0 29.4 15.4 0.0 0.1 3.2 12.6 8.5 3.2 0.7 3.1 1.7 0.0 2.6 3.5 1.4 2.0 0.2 6.9 0.0 8.3 10.5 14.4 0.6 8.3 1.2 0.0 2.4 0.0 3.9 6.3 1.0 0.0 16.3 1.0 9.6 3.9 3.3 2.8 0.0 27.1 6.9 7.0 0.0 0.0 2.8 0.0 35.6 4.3 8.4 7.0 1.2 0.3 0.7 6.8 3.9 0.0 2.8 0.0 3.3 0.3 0.1 10.0 0.4 24.6 5.9 6.8 0.1 0.0 0.0 0.0 8.8 6.2 0.0 14.0 0.0 2.0 0.0 0.0 1.8 2.1 0.1 0.0 29.4 0.0 15.4 2.0 0.1 3.2 8.7 20.6 3.4 17.9 11.3 5.3 6.5 9.6 9.2 8.7 CHST3 "C6ST, C6ST1" ENSG00000122863 "Carbohydrate sulfotransferase 3" Q7LGC8 10 71964365-72013564 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-251 MG: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047523, HPA055704" Enhanced Approved "Golgi apparatus,Cytosol" 510000 "Golgi apparatus, Cytosol" "HPA047523: , HPA055704: " "unprognostic (1.10e-2)" "unprognostic (1.93e-1)" "unprognostic (1.13e-3)" "unprognostic (1.16e-3)" "unprognostic (2.44e-1)" "unprognostic (4.67e-2)" "unprognostic (4.79e-2)" "unprognostic (7.53e-2)" "unprognostic (7.99e-2)" "unprognostic (3.71e-2)" "unprognostic (2.83e-3)" "unprognostic (5.99e-2)" "unprognostic (1.40e-2)" "unprognostic (2.65e-2)" "unprognostic (7.77e-2)" "unprognostic (2.56e-2)" "unprognostic (2.54e-3)" 22.2 11.6 9.2 7.0 19.4 0.7 12.0 2.9 11.6 10.4 9.0 19.4 4.8 1.7 13.7 7.4 8.4 13.6 6.2 11.9 11.3 5.1 8.6 1.8 6.3 2.2 30.1 5.5 25.0 6.1 1.9 4.0 10.0 15.6 10.7 3.3 5.7 6.3 19.5 13.6 7.1 4.0 21.0 16.2 2.9 11.6 19.4 25.2 0.5 7.3 4.8 2.2 7.5 18.5 0.2 0.3 0.8 0.1 0.1 0.2 0.0 6.7 7.3 3.8 9.3 17.3 6.8 0.1 14.4 13.9 8.9 5.9 6.4 13.7 0.0 10.0 17.0 8.9 3.3 9.9 7.1 0.2 2.5 0.0 12.8 6.1 8.8 0.0 0.0 9.4 11.5 8.8 12.1 2.6 2.0 0.0 9.4 0.2 0.0 0.0 1.6 2.4 0.0 4.5 0.0 12.5 7.0 0.2 3.7 10.9 0.2 10.6 0.8 1.4 5.4 11.0 12.7 18.2 28.8 0.0 0.0 0.0 8.0 0.0 7.7 0.3 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.8 0.1 0.0 0.3 0.1 0.0 9.2 19.4 2.9 11.6 11.3 5.1 30.1 5.5 15.6 25.2 CHST7 "C6ST-2, C6ST2" ENSG00000147119 "Carbohydrate sulfotransferase 7" Q9NS84 X 46573784-46598408 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 17.8;HHSteC: 13.2;NTERA-2: 15.8;PC-3: 13.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 15.4" "Group enriched" "Detected in many" 10 "granulocytes: 9.4;monocytes: 8.0;T-cells: 15.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003919, HPA030503" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" "Nucleoplasm, Vesicles" "HPA003919: AB_10601258, HPA030503: " "unprognostic (3.16e-1)" "prognostic favourable (7.20e-4)" "unprognostic (1.11e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" "unprognostic (7.85e-2)" "unprognostic (9.82e-3)" "unprognostic (3.52e-2)" "unprognostic (2.61e-1)" "unprognostic (2.81e-1)" "unprognostic (2.39e-3)" "unprognostic (6.71e-2)" "unprognostic (1.19e-1)" "unprognostic (8.85e-3)" "unprognostic (8.28e-2)" "unprognostic (1.50e-1)" "unprognostic (4.39e-2)" 13.1 7.5 4.9 3.8 6.6 4.7 12.1 4.7 10.3 10.5 4.4 3.6 2.5 2.2 5.0 4.1 4.2 3.2 10.7 25.6 4.1 4.0 3.6 11.0 5.4 3.7 4.5 4.7 27.0 3.4 2.4 3.4 5.9 3.6 3.9 2.2 1.4 2.7 3.7 4.3 5.4 3.3 3.5 1.9 17.1 3.4 3.6 1.8 2.4 4.2 1.4 2.0 4.1 8.7 1.0 1.0 9.4 8.0 0.4 15.4 1.6 4.1 3.4 2.9 2.7 8.5 6.0 0.1 5.7 4.1 1.5 2.0 0.9 1.6 0.0 17.8 2.3 3.1 2.8 1.0 1.3 2.4 6.2 0.8 0.3 3.0 13.2 1.4 0.1 2.0 0.8 2.9 2.4 4.7 0.0 3.6 1.1 1.9 0.5 1.8 15.8 13.2 2.7 2.5 7.4 4.2 0.1 6.8 2.6 0.8 0.2 0.6 1.0 0.3 1.1 4.8 0.5 2.5 2.6 8.5 1.7 1.2 5.3 0.0 0.3 1.2 1.9 0.6 1.4 5.9 1.3 1.0 5.3 2.5 1.0 0.6 1.1 1.0 9.4 0.4 8.0 0.6 15.4 1.6 4.9 6.6 4.7 10.3 4.1 4.0 4.5 4.7 3.6 1.8 CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175723-101251932 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 72.5" "Cell line enhanced" "Detected in all" "Karpas-707: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048902 Uncertain "Secreted - unknown location" "HPA048902: " "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavourable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" 23.2 15.6 14.4 14.6 13.7 15.7 17.7 8.5 11.1 17.7 6.5 9.6 8.6 4.9 15.6 11.6 9.1 14.1 19.0 19.0 11.4 7.5 9.0 8.1 20.6 12.4 15.3 5.5 21.9 6.0 5.9 8.7 72.5 12.9 13.6 7.0 12.1 9.8 10.1 7.3 13.7 6.8 16.4 11.9 18.4 9.3 10.8 13.5 8.3 9.7 9.2 8.7 14.3 20.0 1.9 1.5 8.7 2.4 1.2 3.2 1.0 2.7 3.4 11.7 5.9 6.1 8.2 7.8 6.8 6.0 8.2 8.4 2.9 2.2 6.7 4.0 11.2 7.7 7.7 8.6 9.1 7.4 3.9 13.3 3.9 3.5 7.6 20.1 13.7 7.5 7.3 7.1 6.5 9.7 4.8 68.3 6.2 2.4 2.7 13.8 13.4 2.5 6.2 11.7 9.9 5.7 5.5 2.0 11.0 7.1 3.5 12.3 4.0 24.9 8.1 13.5 7.7 6.3 14.2 12.1 28.0 3.9 10.4 19.1 10.0 0.0 2.4 5.1 2.9 1.5 3.1 1.7 1.8 3.1 1.5 1.9 1.0 1.9 8.7 1.2 1.6 0.9 3.2 1.0 14.4 13.7 8.5 11.1 11.4 7.5 15.3 5.5 12.9 13.5 CHSY3 "CHSY-2, CSS3" ENSG00000198108 "Chondroitin sulfate synthase 3" Q70JA7 5 129904472-130186634 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 12.5;ASC TERT1: 11.1;HSkMC: 7.2;TIME: 6.7;U-138 MG: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044612 Uncertain "Intracellular and membrane" "HPA044612: AB_10795883" "unprognostic (3.43e-2)" "unprognostic (6.28e-3)" "unprognostic (1.76e-2)" "unprognostic (5.83e-2)" "unprognostic (5.88e-2)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (9.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.08e-6)" "unprognostic (5.22e-3)" "unprognostic (9.93e-2)" "unprognostic (4.61e-3)" "unprognostic (1.74e-2)" 11.7 1.6 7.0 2.7 8.9 0.3 5.7 0.4 10.4 12.5 1.7 2.1 0.0 1.5 4.2 1.6 1.8 2.6 7.2 3.0 4.8 2.2 1.0 4.8 4.6 1.4 2.1 8.9 1.1 1.1 2.1 0.9 5.6 1.0 1.4 1.6 6.3 1.3 1.8 2.2 2.8 1.3 5.2 1.5 1.9 1.5 1.9 2.1 0.0 2.9 1.3 1.3 3.9 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.1 0.0 12.5 11.1 1.0 2.7 0.1 0.4 0.4 0.0 0.1 0.0 0.2 4.1 0.0 0.0 0.1 0.0 0.0 1.5 1.7 5.5 0.4 1.2 0.0 0.0 7.2 0.0 0.1 1.1 2.9 0.0 1.8 4.8 0.0 0.0 0.0 0.6 1.1 0.4 5.3 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.2 0.2 0.4 6.7 13.4 2.8 0.1 1.8 0.0 0.0 0.0 0.3 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 7.0 8.9 0.4 10.4 4.8 2.2 2.1 8.9 1.0 2.1 CHUK "IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16" ENSG00000213341 "Conserved helix-loop-helix ubiquitous kinase" O15111 10 100188298-100229619 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001402, CAB004240, CAB018564" Approved Supported Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "CAB004240: AB_627784, CAB018564: AB_649197, HPA001402: AB_1079125" "unprognostic (8.61e-3)" "unprognostic (1.70e-1)" "unprognostic (3.74e-2)" "unprognostic (3.01e-1)" "unprognostic (3.02e-2)" "unprognostic (5.93e-2)" "unprognostic (4.02e-2)" "unprognostic (2.09e-1)" "unprognostic (8.58e-2)" "unprognostic (8.39e-2)" "unprognostic (6.73e-2)" "unprognostic (1.49e-1)" "prognostic favourable (1.27e-4)" "unprognostic (2.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-3)" "unprognostic (2.22e-1)" 16.6 16.6 14.0 14.3 18.9 21.3 14.2 16.0 15.8 11.8 15.0 13.0 13.9 16.1 14.7 12.4 13.5 12.0 11.7 14.5 13.3 17.6 27.2 35.8 14.0 20.8 17.9 6.9 11.4 14.5 19.6 18.2 14.2 16.4 12.9 17.6 9.5 13.9 12.5 23.6 11.0 20.6 16.1 18.6 18.7 15.1 12.5 15.6 22.5 14.5 11.7 15.5 13.8 13.6 3.7 3.4 7.2 4.8 4.0 4.3 1.4 15.6 13.2 13.6 20.2 13.1 11.8 10.5 19.9 19.6 18.6 22.8 14.8 9.3 21.2 11.8 13.5 15.5 22.6 10.6 21.0 22.5 19.5 14.1 10.5 16.3 11.2 26.0 20.7 9.4 11.3 21.5 21.0 13.2 15.9 17.6 20.3 9.5 20.5 16.1 8.8 9.7 13.4 15.1 9.7 11.8 10.1 8.1 12.1 10.8 8.4 17.3 16.7 15.9 13.9 11.7 13.2 12.7 22.6 20.8 18.7 20.7 12.8 21.2 9.2 2.6 3.0 5.1 2.4 4.8 4.0 3.7 3.0 4.3 3.4 2.1 3.3 4.2 7.2 4.0 3.2 2.1 2.8 1.4 14.0 18.9 16.0 15.8 13.3 17.6 17.9 6.9 16.4 15.6 CIITA "C2TA, MHC2TA, NLRA" ENSG00000179583 "Class II major histocompatibility complex transactivator" P33076 16 10866222-10943021 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Kinase, Transferase" "Cancer-related genes, Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 67.2" "Cell line enhanced" "Detected in some" "HDLM-2: 22.8;REH: 40.0;U-698: 11.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016084, HPA054757" Enhanced Supported Nucleoplasm Nucleoplasm "CAB016084: AB_627261, HPA054757: " "unprognostic (1.45e-3)" "unprognostic (1.38e-2)" "unprognostic (8.22e-3)" "unprognostic (1.12e-2)" "unprognostic (5.66e-2)" "unprognostic (2.88e-3)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" "unprognostic (1.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.23e-1)" "unprognostic (3.72e-1)" "unprognostic (1.64e-2)" "unprognostic (2.72e-2)" "unprognostic (6.33e-3)" "unprognostic (2.74e-1)" "unprognostic (1.05e-2)" 8.0 5.9 4.6 47.7 7.1 4.3 6.8 1.5 5.5 6.3 3.7 10.6 4.2 10.4 8.1 10.4 4.8 5.2 8.1 4.9 4.7 3.5 8.8 2.9 15.0 27.0 9.4 1.1 2.5 3.5 1.9 4.0 1.2 6.6 5.5 4.3 5.5 13.3 4.3 2.9 4.4 17.4 3.7 15.6 25.9 6.2 1.5 7.4 12.6 6.1 5.2 67.2 6.3 6.8 27.3 19.0 6.5 11.9 0.7 0.5 1.7 0.1 0.2 0.3 0.3 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.3 5.5 5.0 0.8 0.0 0.9 0.0 0.0 0.1 22.8 0.2 2.9 1.0 0.6 0.0 0.4 0.4 1.0 0.0 0.1 0.0 0.0 0.3 2.0 0.1 0.3 0.2 0.4 0.1 0.1 40.0 0.3 3.5 0.0 1.6 0.9 0.1 0.9 0.3 0.9 0.5 1.6 0.3 2.1 0.3 0.6 0.2 8.4 0.6 11.8 7.5 0.5 6.8 0.2 11.9 6.5 0.3 9.5 0.1 17.9 0.1 0.5 17.7 27.3 0.1 0.2 2.8 0.7 10.0 19.0 0.4 1.7 4.6 7.1 1.5 5.5 4.7 3.5 9.4 1.1 6.6 7.4 CIT "CITK, CRIK, KIAA0949, STK21" ENSG00000122966 "Citron rho-interacting serine/threonine kinase" O14578 12 119685790-119877291 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;brain: 35.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA019082, HPA048812, HPA075506" Uncertain Approved Cytosol Cytosol "HPA019082: AB_1846803, HPA048812: , HPA075506: " "unprognostic (5.64e-2)" "unprognostic (5.00e-2)" "unprognostic (8.16e-2)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (3.61e-6)" "unprognostic (6.02e-2)" "unprognostic (7.78e-2)" "unprognostic (4.42e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-2)" "unprognostic (2.55e-3)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (1.70e-1)" "unprognostic (3.30e-1)" 1.4 4.4 14.7 3.3 14.0 15.3 1.6 12.7 35.0 1.6 4.6 2.9 0.0 4.0 1.3 1.5 3.2 0.9 1.6 1.0 9.8 5.7 5.7 1.4 3.0 3.4 3.2 21.9 0.7 0.7 1.2 2.9 2.6 7.4 1.0 5.3 0.6 1.3 1.0 1.3 5.1 3.5 2.6 5.0 5.6 3.5 8.3 9.5 5.9 1.5 0.1 4.9 1.7 1.7 0.4 0.0 0.0 0.1 0.0 1.2 0.8 15.0 13.5 11.9 11.2 1.1 3.3 7.0 11.5 9.6 12.1 9.1 8.6 6.2 10.8 6.2 8.9 9.4 8.1 6.7 16.7 7.7 5.9 13.7 8.7 5.3 0.1 7.2 12.6 0.7 0.7 14.4 8.9 9.2 8.7 9.2 11.3 7.5 13.0 11.0 6.4 9.1 11.9 21.6 3.6 2.4 6.6 8.5 4.7 19.1 3.7 9.1 13.5 5.2 7.0 15.1 13.9 10.3 12.5 6.3 7.0 7.4 10.0 7.9 23.3 0.0 0.0 0.0 0.4 0.1 0.0 0.4 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 14.7 14.0 12.7 35.0 9.8 5.7 3.2 21.9 7.4 9.5 CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519659-103523111 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 158.5" "Cell line enhanced" "Detected in many" "CACO-2: 53.1;HEK 293: 135.1;SCLC-21H: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 10 "non-classical monocyte: 50.0" "Lineage enriched" "Detected in many" 17 "monocytes: 50.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001254, CAB047313" Enhanced Supported Cytosol 50000000 Cytosol "CAB047313: , HPA001254: AB_1078528" "unprognostic (9.97e-2)" "unprognostic (1.33e-3)" "unprognostic (4.25e-3)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (3.62e-2)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (4.24e-1)" "unprognostic (4.60e-2)" "unprognostic (2.68e-3)" "unprognostic (9.89e-3)" "prognostic favourable (4.02e-8)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-2)" "unprognostic (2.13e-1)" 32.4 27.3 75.4 10.4 114.6 3.1 5.3 94.3 158.5 29.1 121.5 51.4 23.8 17.6 37.3 8.9 28.6 35.7 17.8 36.4 60.7 43.2 26.7 3.4 12.8 3.6 63.4 93.3 15.8 10.2 20.3 9.7 3.7 63.3 107.5 55.0 43.9 18.3 92.1 19.1 14.4 17.5 53.2 31.9 3.6 66.7 22.1 50.9 0.0 19.8 7.8 3.9 43.0 13.0 0.0 2.9 1.4 50.0 0.0 0.1 0.9 0.3 6.7 26.9 1.4 0.2 0.2 0.5 2.9 0.0 0.3 0.1 53.1 0.8 0.0 3.2 2.0 5.9 7.8 0.1 0.0 1.2 135.1 10.0 29.7 18.2 1.1 0.0 8.2 1.0 0.0 0.2 0.1 0.0 17.4 0.4 0.4 2.2 0.2 0.3 10.5 21.0 1.7 0.5 27.6 4.9 0.2 76.9 31.6 5.7 0.9 2.1 2.5 4.1 0.1 0.1 5.2 0.5 12.6 1.3 0.3 0.9 0.7 0.2 0.9 0.3 0.1 1.4 0.0 5.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.1 0.0 50.0 0.0 0.1 0.9 75.4 114.6 94.3 152.7 60.7 43.2 63.4 93.3 63.3 50.9 CKM CKMM ENSG00000104879 "Creatine kinase, M-type" P06732 19 45306414-45322977 "Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 1374.7;tongue: 354.9" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 36.8" "Group enriched" "Detected in many" 33 "head and neck cancer: 64.4;prostate cancer: 14.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 2.8;intermediate monocyte: 1.1;myeloid DC: 2.1" "Group enriched" "Detected in many" 25 "dendritic cells: 2.1;monocytes: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047859 Enhanced 190000000 "HPA047859: " "unprognostic (3.51e-1)" "unprognostic (7.63e-2)" "unprognostic (2.61e-2)" "unprognostic (4.14e-1)" "unprognostic (7.68e-3)" "unprognostic (4.04e-3)" "unprognostic (1.85e-2)" "unprognostic (4.23e-2)" "unprognostic (5.19e-2)" "unprognostic (1.81e-1)" "unprognostic (5.00e-1)" "unprognostic (9.46e-3)" "unprognostic (9.67e-8)" "unprognostic (3.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.33e-1)" "unprognostic (1.95e-1)" 13.9 0.1 0.2 0.1 0.2 0.1 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.1 23.5 21.1 0.1 0.1 187.9 0.2 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.0 2.8 0.1 0.8 17.6 0.2 1374.7 0.2 0.2 0.2 0.3 0.1 0.5 0.3 0.0 0.0 11.1 354.9 24.8 0.2 0.1 0.0 2.1 0.0 2.8 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.9 0.0 0.1 8.7 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 3.3 0.1 0.1 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 CKMT1A CKMT1 ENSG00000223572 "Creatine kinase, mitochondrial 1A" P12532 15 43692886-43699222 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.2;esophagus: 19.9;intestine: 25.5" "Cell line enhanced" "Detected in many" "HaCaT: 42.6;hTCEpi: 19.3;SCLC-21H: 15.1;SK-BR-3: 33.5;T-47d: 29.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043491 Uncertain "Intracellular and membrane" 2100000 "HPA043491: " "unprognostic (2.04e-2)" "unprognostic (2.53e-2)" "unprognostic (1.17e-1)" "unprognostic (4.02e-3)" "unprognostic (3.80e-1)" "unprognostic (7.44e-2)" "unprognostic (2.21e-1)" "unprognostic (3.10e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.51e-2)" "unprognostic (3.78e-9)" "unprognostic (3.52e-2)" "unprognostic (1.03e-1)" "unprognostic (7.37e-2)" "unprognostic (1.73e-3)" 0.0 0.7 4.8 1.9 6.3 0.0 2.1 17.2 12.6 1.8 25.5 24.7 0.0 0.0 19.9 0.4 3.0 0.0 5.6 7.9 0.9 0.0 0.0 0.0 5.0 0.0 0.1 2.1 1.4 2.5 0.5 24.1 7.2 0.0 0.0 13.0 21.7 0.9 1.1 0.0 7.8 0.0 0.6 4.4 1.4 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.3 0.0 10.6 0.0 0.0 0.0 0.0 2.2 7.3 0.0 0.4 0.0 42.6 6.1 12.5 0.0 0.0 4.7 0.0 0.7 0.2 0.0 0.0 2.0 0.0 19.3 0.0 3.3 0.0 1.9 0.0 0.0 9.9 0.0 0.0 3.0 2.3 0.0 0.0 1.9 2.0 1.5 15.1 5.9 0.0 33.5 2.2 29.9 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CKMT1B "CKMT, CKMT1, UMTCK" ENSG00000237289 "Creatine kinase, mitochondrial 1B" P12532 15 43593054-43604901 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.7;intestine: 28.1" "Cell line enhanced" "Detected in many" "HaCaT: 40.4;HBEC3-KT: 15.5;hTCEpi: 20.8;SCLC-21H: 15.6;SK-BR-3: 49.7;T-47d: 28.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043491 Uncertain "Intracellular and membrane" 2100000 "HPA043491: " "unprognostic (3.47e-2)" "unprognostic (9.73e-3)" "unprognostic (3.10e-1)" "prognostic unfavourable (2.55e-5)" "unprognostic (1.29e-1)" "unprognostic (1.96e-1)" "unprognostic (5.19e-2)" "unprognostic (2.84e-1)" "unprognostic (3.64e-1)" "unprognostic (5.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-2)" "unprognostic (2.26e-8)" "unprognostic (1.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.43e-2)" "unprognostic (4.36e-2)" 0.0 0.3 5.4 1.6 8.8 0.0 1.6 52.7 13.6 0.7 28.1 22.4 0.0 0.0 13.8 0.2 2.8 0.0 6.8 7.4 0.9 0.0 0.0 0.0 5.4 0.0 0.2 1.4 1.3 3.7 0.6 23.1 4.8 0.0 0.0 7.6 16.2 1.2 1.8 0.0 10.0 0.0 1.7 4.1 1.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 9.8 0.0 0.0 0.0 0.0 2.3 6.9 0.0 0.3 0.0 40.4 8.1 15.5 0.0 0.1 4.7 0.0 1.0 1.0 0.0 0.0 2.3 0.0 20.8 0.0 1.8 0.0 2.6 0.0 0.0 9.8 0.0 0.0 3.2 4.3 0.0 0.0 0.2 0.7 1.0 15.6 5.5 0.2 49.7 2.9 28.9 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CKMT2 SMTCK ENSG00000131730 "Creatine kinase, mitochondrial 2" P17540 5 81233285-81266397 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "heart muscle: 153.2;skeletal muscle: 182.4;tongue: 103.6" "Cell line enhanced" "Detected in some" "ASC diff: 3.6;BEWO: 5.9;Hep G2: 5.1;HHSteC: 3.9;T-47d: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 9 "NK-cell: 3.8" "Lineage enriched" "Detected in single" 9 "NK-cells: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051880 Enhanced 3200000 "HPA051880: " "unprognostic (3.64e-3)" "unprognostic (1.15e-1)" "unprognostic (2.82e-3)" "unprognostic (1.88e-2)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (3.57e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.75e-3)" 2.5 5.0 1.3 0.3 1.9 0.2 0.8 0.4 1.2 1.2 0.5 1.2 2.5 0.3 1.3 11.5 3.0 1.2 1.5 153.2 1.5 0.9 2.7 0.3 0.4 0.3 2.3 1.4 1.6 1.3 1.1 0.7 0.3 4.1 2.0 0.3 2.5 9.1 2.1 182.4 0.5 0.6 1.4 2.8 0.4 2.1 0.9 1.5 0.0 3.3 103.6 2.9 1.0 0.6 0.4 0.1 0.0 0.4 3.8 0.3 0.0 0.1 0.9 0.0 0.9 3.6 0.7 5.9 0.1 0.0 0.0 0.0 0.3 0.3 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.5 3.1 0.0 0.7 5.1 3.9 0.4 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.2 0.1 0.7 0.4 0.8 0.9 0.0 0.0 0.1 0.7 0.7 0.5 0.4 0.8 9.5 0.4 0.8 0.5 0.9 0.5 0.3 0.1 0.1 0.8 0.4 0.5 0.9 0.0 0.2 0.0 0.1 0.4 0.0 0.1 0.3 0.0 0.0 0.4 0.1 0.2 0.0 3.8 0.0 0.1 0.2 0.0 1.3 1.9 0.4 1.2 1.5 0.9 2.3 1.4 4.1 1.5 CLK1 ENSG00000013441 "CDC like kinase 1" P49759 2 200853009-200864744 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033141, HPA062405" Approved Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "CAB033141: AB_1121713, HPA062405: " "unprognostic (9.79e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (9.19e-2)" "unprognostic (4.50e-3)" "unprognostic (1.52e-1)" "unprognostic (2.77e-3)" "unprognostic (1.78e-2)" "unprognostic (2.09e-2)" "unprognostic (1.09e-2)" "unprognostic (5.63e-3)" "unprognostic (2.03e-3)" "unprognostic (9.66e-2)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "prognostic favourable (2.28e-4)" 26.3 55.1 27.8 30.5 43.4 97.6 40.2 40.1 40.7 42.2 23.0 19.9 39.1 12.9 29.1 34.5 26.3 19.1 35.8 26.7 31.0 21.9 21.8 35.3 28.2 30.1 56.0 23.1 48.1 20.9 36.6 41.5 40.0 34.4 34.3 16.5 13.7 25.6 37.1 27.3 32.1 14.9 36.8 55.2 32.4 15.1 12.4 52.6 25.0 30.4 20.2 25.6 51.2 71.8 13.2 9.8 26.2 6.2 6.5 14.4 7.4 8.1 6.1 10.3 3.1 11.7 12.9 8.1 8.8 12.6 9.0 12.0 11.4 5.3 2.8 6.0 5.5 8.8 13.0 4.1 18.5 12.4 11.4 8.3 15.5 14.1 7.0 8.7 14.2 5.9 18.6 11.3 19.9 5.2 10.0 36.8 12.8 5.5 10.2 26.4 6.5 14.0 10.4 12.2 14.6 6.2 5.3 10.4 8.2 7.7 2.9 12.8 2.4 6.0 8.0 10.1 6.9 9.7 9.7 21.7 9.0 6.5 6.5 7.1 6.8 26.2 6.2 13.3 13.6 4.4 13.1 13.2 12.8 12.1 4.1 10.1 14.4 11.4 12.7 6.5 4.2 9.8 13.0 7.4 27.8 43.4 40.1 40.7 31.0 21.9 56.0 23.1 34.4 52.6 CLK2 clk2 ENSG00000176444 "CDC like kinase 2" P49760 1 155262868-155278491 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055366, HPA059507" Approved Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA055366: , HPA059507: " "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavourable (3.77e-4)" "unprognostic (2.84e-2)" "unprognostic (3.16e-1)" "unprognostic (1.75e-1)" "prognostic unfavourable (2.82e-4)" "unprognostic (2.38e-1)" "unprognostic (2.36e-1)" "unprognostic (1.36e-2)" "unprognostic (7.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavourable (2.95e-9)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "prognostic favourable (5.43e-4)" 15.3 16.6 14.6 15.0 19.0 12.9 17.1 33.1 20.2 22.3 18.0 18.7 18.1 14.5 22.6 19.9 15.5 18.2 13.9 11.8 17.1 7.3 17.3 18.2 14.7 22.2 16.9 16.9 24.7 15.9 29.2 21.6 19.2 13.5 22.1 13.5 16.1 16.4 18.2 10.4 21.4 15.6 17.0 13.5 27.0 13.7 13.7 20.3 18.1 22.9 8.0 22.2 16.7 20.1 2.8 1.9 4.8 1.7 0.7 4.1 1.1 6.0 5.2 18.9 5.8 9.5 5.1 16.1 5.4 6.6 4.2 4.2 5.5 4.3 13.1 7.5 3.7 8.7 9.4 7.0 4.0 9.5 7.4 10.4 5.4 7.0 8.2 12.9 10.5 4.1 6.4 6.1 12.3 7.3 14.6 9.1 6.3 10.4 8.8 7.7 12.3 7.4 9.8 11.4 14.1 10.6 13.5 9.0 12.8 2.0 6.5 5.0 9.9 15.9 4.8 2.6 6.9 4.7 4.5 17.4 14.8 11.9 5.1 9.3 2.9 4.8 1.7 3.4 2.0 0.8 2.9 2.8 3.4 1.8 1.8 2.4 3.4 4.1 2.1 0.7 0.8 1.9 1.7 1.1 14.6 19.0 33.1 20.2 17.1 7.3 16.9 16.9 13.5 20.3 CLK3 clk3 ENSG00000179335 "CDC like kinase 3" P49761 15 74598500-74645414 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046817 Approved Supported "Nucleoplasm,Intermediate filaments" "Nucleoplasm, Intermediate filaments" "HPA046817: AB_10964124" "unprognostic (4.10e-2)" "unprognostic (8.43e-2)" "prognostic unfavourable (2.05e-6)" "unprognostic (1.91e-3)" "unprognostic (7.91e-2)" "unprognostic (5.76e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" "unprognostic (1.95e-1)" "unprognostic (2.54e-1)" "unprognostic (8.14e-3)" "prognostic unfavourable (5.92e-4)" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "unprognostic (9.73e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-2)" 20.9 17.2 15.7 24.7 22.5 62.7 31.1 23.4 18.8 24.9 24.6 23.1 16.4 18.6 24.1 17.7 25.3 17.3 21.2 16.4 17.8 13.5 17.2 16.0 19.6 21.9 29.3 14.5 23.7 21.8 19.0 19.9 27.9 16.7 20.6 14.4 19.9 24.8 20.9 28.4 24.1 20.7 19.8 19.2 23.8 19.6 31.5 23.3 28.8 21.0 12.0 23.7 23.2 19.8 38.9 36.0 60.7 46.0 43.6 43.4 39.7 22.3 14.2 18.8 10.5 24.2 18.5 14.8 15.3 24.2 21.9 26.9 19.2 14.8 20.4 11.3 13.6 15.8 35.0 14.7 14.3 28.9 19.1 25.0 21.1 13.3 38.5 6.7 19.4 23.2 29.3 28.7 24.0 23.9 12.1 14.9 12.7 15.8 19.8 22.7 12.0 10.0 16.1 9.0 13.3 17.0 16.2 10.6 12.4 12.2 13.6 13.5 12.9 13.5 11.0 13.0 10.0 8.1 20.0 24.4 19.6 16.7 11.4 33.0 16.3 32.9 34.4 45.0 38.5 37.4 37.4 37.7 41.1 39.7 31.9 38.9 42.1 40.1 60.7 43.6 46.0 36.0 43.4 39.7 15.7 22.5 23.4 18.8 17.8 13.5 29.3 14.5 16.7 23.3 CLK4 ENSG00000113240 "CDC like kinase 4" Q9HAZ1 5 178602664-178630615 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043746 Approved Approved "Actin filaments" "Actin filaments" "HPA043746: " "unprognostic (9.46e-2)" "unprognostic (2.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.44e-2)" "unprognostic (1.59e-1)" "unprognostic (7.16e-3)" "unprognostic (2.67e-1)" "unprognostic (2.04e-2)" "unprognostic (4.37e-2)" "unprognostic (5.92e-2)" "unprognostic (2.90e-3)" "unprognostic (9.62e-3)" "unprognostic (1.13e-2)" "unprognostic (1.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-3)" 12.2 16.4 17.0 17.4 18.4 11.4 17.3 53.8 24.1 17.9 12.2 11.9 18.3 12.4 17.0 16.4 10.5 11.0 13.1 11.4 15.9 9.5 11.8 16.0 10.9 20.3 21.2 12.7 17.4 16.2 15.4 20.2 13.9 16.3 16.7 8.9 10.8 14.4 17.0 20.6 19.5 11.3 11.3 25.8 17.0 11.0 15.7 22.0 15.0 15.8 9.7 12.7 11.4 18.0 13.2 7.8 16.1 6.1 7.7 13.8 5.2 6.8 6.3 5.9 8.5 17.6 14.8 9.7 6.7 7.6 4.0 7.4 6.7 5.5 3.9 5.4 2.8 9.1 7.5 5.4 6.6 14.1 5.9 1.5 11.9 8.2 6.6 3.1 5.0 6.7 7.9 6.4 8.7 2.7 3.5 11.7 5.1 2.8 4.0 11.4 3.0 3.9 4.0 5.2 5.7 4.0 2.1 6.6 4.4 7.5 4.1 6.9 4.3 6.6 5.6 8.2 3.0 4.2 7.1 7.7 2.9 3.0 5.9 7.6 4.2 6.5 6.1 12.0 10.0 4.1 13.2 13.2 10.3 8.9 5.9 10.4 13.8 10.6 16.1 7.7 4.4 7.8 9.5 5.2 17.0 18.4 53.8 24.1 15.9 9.5 21.2 12.7 16.3 22.0 CLOCK "bHLHe8, KAT13D, KIAA0334" ENSG00000134852 "Clock circadian regulator" O15516 4 55427903-55547138 "Enzymes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001867, HPA027565" Supported Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA001867: AB_1078537, HPA027565: AB_1846975" "unprognostic (1.30e-2)" "unprognostic (9.02e-2)" "unprognostic (4.25e-3)" "unprognostic (2.48e-1)" "unprognostic (3.94e-2)" "unprognostic (2.00e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (4.52e-2)" "unprognostic (4.32e-2)" "unprognostic (3.01e-2)" "unprognostic (5.96e-2)" "unprognostic (4.07e-2)" "unprognostic (8.31e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "unprognostic (7.16e-2)" 9.3 9.2 7.8 5.8 11.7 1.7 8.4 16.2 14.3 12.5 9.5 5.2 9.2 7.1 10.5 8.4 13.9 8.1 6.7 10.5 7.9 7.9 12.4 9.1 8.2 9.4 7.0 9.8 11.7 8.6 18.7 21.9 8.5 8.4 9.7 8.4 5.6 8.2 9.2 16.1 9.4 12.6 13.8 8.3 9.1 9.6 18.5 5.0 4.0 14.7 5.9 5.2 8.4 17.1 2.5 3.6 0.6 3.0 2.9 4.7 1.4 13.4 5.9 5.3 8.3 8.0 8.1 2.6 13.9 11.4 9.7 9.0 3.7 10.7 3.6 7.2 16.1 11.3 6.8 10.8 16.5 4.4 2.4 2.9 6.2 4.6 7.1 4.7 3.4 4.7 10.7 13.4 13.2 9.1 6.6 7.4 14.6 7.4 2.6 2.6 3.8 6.8 1.7 6.1 2.4 7.5 7.3 5.2 4.7 10.0 12.4 6.3 4.2 2.6 12.5 13.2 14.1 4.3 18.7 6.7 4.8 2.3 11.7 4.2 10.4 0.0 3.0 0.6 2.8 3.0 4.7 1.4 3.2 2.5 3.6 2.5 1.9 2.4 0.6 2.9 2.7 2.1 3.1 1.4 7.8 11.7 16.2 14.3 7.9 7.9 7.0 9.8 8.4 5.0 CLP1 "hClp1, HEAB" ENSG00000172409 "Cleavage and polyadenylation factor I subunit 1" Q92989 11 57648992-57661868 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Kinase, Transferase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057770 Supported Supported Nucleoplasm Nucleoplasm "HPA057770: " "unprognostic (1.33e-1)" "unprognostic (7.90e-2)" "unprognostic (1.11e-3)" "unprognostic (2.13e-2)" "unprognostic (4.90e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-3)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (1.66e-2)" "unprognostic (8.82e-2)" "unprognostic (7.58e-2)" "unprognostic (8.31e-3)" "unprognostic (3.71e-2)" "unprognostic (1.75e-1)" "unprognostic (8.78e-2)" "unprognostic (3.07e-1)" 10.8 11.7 7.0 11.2 8.8 23.5 9.6 7.2 10.9 8.5 9.3 5.6 7.6 9.0 12.0 10.0 13.6 10.1 6.2 8.1 6.0 4.5 9.9 12.8 8.7 9.9 6.5 5.1 7.3 11.8 7.2 6.8 17.3 6.1 10.5 9.2 5.6 10.3 8.1 16.7 11.8 11.7 11.2 5.0 15.4 11.5 11.3 6.5 15.4 11.8 10.8 13.2 8.8 6.9 16.2 19.0 23.7 19.1 12.8 20.9 11.6 14.0 14.1 14.1 14.9 15.6 10.4 13.5 13.8 15.3 20.9 17.6 13.0 12.7 23.3 16.9 11.5 17.3 19.5 22.3 23.3 15.8 11.4 12.6 10.1 14.7 11.9 19.3 15.3 11.5 15.9 17.7 12.7 18.9 20.4 8.1 16.8 10.0 13.9 22.0 21.6 14.8 15.0 22.8 24.7 11.2 10.0 7.7 15.1 11.7 12.1 18.9 22.5 14.8 13.1 11.3 15.2 19.2 11.1 13.0 16.5 25.4 12.3 10.4 11.9 23.7 19.1 19.9 17.6 16.0 20.9 16.2 15.8 17.8 19.0 14.1 18.2 16.6 22.3 12.8 15.7 11.0 16.0 11.6 7.0 8.8 7.2 10.9 6.0 4.5 6.5 5.1 6.1 6.5 CLPB "ANKCLB, FLJ13152, HSP78, SKD3" ENSG00000162129 "ClpB homolog, mitochondrial AAA ATPase chaperonin" Q9H078 11 72285495-72434680 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 87.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 18.3" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039005, HPA039006, HPA064571" Enhanced "HPA039005: AB_2676305, HPA039006: AB_10672767, HPA064571: " "unprognostic (9.36e-2)" "unprognostic (1.06e-2)" "unprognostic (2.51e-1)" "unprognostic (1.23e-1)" "unprognostic (2.99e-1)" "unprognostic (2.05e-2)" "unprognostic (8.22e-2)" "unprognostic (8.37e-2)" "unprognostic (2.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.01e-2)" "unprognostic (1.18e-1)" "prognostic favourable (8.36e-8)" "unprognostic (9.29e-2)" "unprognostic (1.25e-1)" "unprognostic (5.83e-2)" "unprognostic (3.28e-2)" 4.4 6.1 5.7 4.8 7.2 7.9 3.4 5.6 10.5 3.1 3.1 6.7 2.5 3.2 3.8 3.1 3.7 2.9 2.9 4.1 4.9 4.1 6.7 8.5 3.7 3.0 5.7 5.9 3.2 5.5 8.6 3.4 6.5 7.9 2.7 3.1 3.1 4.2 3.3 6.5 2.8 2.9 4.5 3.9 3.9 3.7 87.9 6.4 2.7 4.7 1.8 2.9 3.7 3.0 1.6 18.3 4.0 11.7 1.8 2.4 5.2 6.4 18.5 5.8 11.9 7.9 5.8 15.0 7.0 4.3 10.5 7.9 24.7 9.8 16.7 16.1 6.6 13.8 15.5 15.3 12.9 15.1 11.6 14.1 19.2 14.7 6.8 14.1 25.1 7.7 5.1 18.6 18.8 11.8 19.1 11.8 7.5 17.1 12.7 13.4 6.1 18.5 11.6 8.7 7.2 6.1 11.1 14.6 11.1 9.5 21.9 16.3 11.3 12.3 9.2 15.0 9.7 15.1 13.5 5.7 8.1 9.5 8.0 12.0 11.4 4.0 11.7 0.6 2.4 9.3 2.4 1.5 1.4 2.1 18.3 1.6 1.8 1.4 1.0 1.8 5.2 3.3 0.8 5.2 5.7 7.2 5.6 10.5 4.9 4.1 5.7 5.9 7.9 6.4 CLPP ENSG00000125656 "Caseinolytic mitochondrial matrix peptidase proteolytic subunit" Q16740 19 6361452-6368910 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010649 Supported Supported Mitochondria Mitochondria "HPA010649: AB_1078538" "unprognostic (2.28e-1)" "unprognostic (7.14e-2)" "unprognostic (2.82e-1)" "unprognostic (4.34e-2)" "unprognostic (2.17e-2)" "unprognostic (1.15e-2)" "unprognostic (6.17e-3)" "unprognostic (7.43e-2)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "prognostic favourable (6.50e-4)" "unprognostic (1.21e-1)" "unprognostic (5.65e-2)" "unprognostic (6.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.86e-3)" 22.1 27.3 18.4 22.5 18.8 20.1 19.9 16.6 20.9 16.1 23.2 17.9 22.2 25.4 16.9 15.1 26.6 15.3 19.2 28.9 17.4 16.7 28.5 64.7 15.5 35.5 19.0 15.2 23.7 32.7 11.6 18.5 18.4 13.6 19.1 14.1 18.6 26.3 23.4 73.1 17.8 26.0 14.8 16.7 21.2 21.3 21.1 11.4 54.8 27.0 25.1 25.3 20.7 23.2 29.7 37.5 14.9 20.0 27.6 46.3 32.9 31.6 21.1 15.4 28.1 9.7 13.5 16.0 18.8 13.8 26.8 24.0 16.9 11.6 31.9 29.3 15.0 19.8 15.2 23.7 10.1 33.1 47.9 23.5 18.6 25.0 26.3 21.2 31.1 17.1 17.4 18.6 20.8 26.0 23.2 43.2 17.5 37.0 36.3 22.2 22.2 49.4 25.6 18.6 48.3 19.9 17.7 25.5 24.4 11.9 29.1 27.6 15.0 30.4 18.1 17.7 16.4 41.6 35.4 55.6 46.4 30.7 24.3 29.9 28.1 5.5 20.0 10.5 28.0 17.7 33.2 28.3 39.9 34.5 24.1 29.7 35.2 34.1 14.9 27.6 12.1 37.5 46.3 32.9 18.4 18.8 16.6 20.9 17.4 16.7 19.0 15.2 13.6 11.4 CLYBL CLB ENSG00000125246 "Citrate lyase beta like" Q8N0X4 13 99606669-99897134 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 57.7" "Cell line enhanced" "Detected in many" "SCLC-21H: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039959, HPA040691" Enhanced Approved Cytosol Cytosol "HPA039959: AB_10793857, HPA040691: AB_10794746" "unprognostic (1.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.30e-3)" "unprognostic (7.57e-3)" "unprognostic (3.69e-1)" "unprognostic (2.90e-2)" "unprognostic (1.57e-3)" "unprognostic (2.91e-1)" "unprognostic (2.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.49e-2)" "unprognostic (2.85e-1)" "prognostic favourable (6.66e-16)" "unprognostic (3.74e-2)" "unprognostic (5.41e-2)" "unprognostic (4.78e-2)" "unprognostic (7.82e-2)" 4.2 11.6 6.2 10.4 9.4 2.6 6.0 6.7 6.4 4.6 11.2 3.8 4.8 13.6 5.2 7.6 6.4 4.7 8.3 12.3 5.1 6.3 35.0 57.7 4.7 9.6 7.9 8.6 3.5 15.0 6.1 5.7 2.2 12.5 4.2 12.3 8.9 8.7 5.5 22.2 5.7 12.5 8.6 4.5 5.5 4.8 10.7 4.3 4.6 7.0 13.3 8.2 4.9 4.4 11.0 7.5 1.2 6.7 9.2 16.7 5.5 0.2 1.3 9.8 4.4 4.6 4.3 2.1 0.4 0.9 0.8 1.5 0.2 7.2 1.7 2.8 0.5 2.2 0.8 1.6 1.1 8.6 1.4 10.9 2.6 6.7 3.2 5.8 0.8 2.3 4.9 0.1 3.8 1.2 1.5 5.7 0.9 2.4 2.6 8.1 6.3 2.0 3.4 0.4 4.0 9.7 0.6 31.7 4.8 1.9 2.2 1.9 4.7 7.6 0.1 0.4 1.1 0.8 1.5 13.3 2.6 0.3 6.8 8.6 1.3 1.2 3.3 0.3 7.5 6.7 9.0 10.9 13.3 10.6 6.7 11.0 10.3 12.1 0.5 9.2 3.2 7.5 16.7 5.5 6.2 9.4 6.7 6.4 5.1 6.3 7.9 8.6 12.5 4.3 CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 1.6;BEWO: 1.5;HL-60: 1.7;TIME: 1.5;U-937: 3.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "T-reg: 1.5" "Lineage enriched" "Detected in single" 4 "T-cells: 1.5" "Low region specificity" "Detected in single" "CAB000363, HPA052634" Enhanced "Secreted to blood" 3000000 "CAB000363: AB_2083616, HPA052634: " "unprognostic (1.37e-1)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (7.07e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.21e-1)" "unprognostic (8.91e-3)" "unprognostic (4.19e-3)" "unprognostic (1.29e-4)" "unprognostic (2.52e-3)" "unprognostic (7.78e-2)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" 12.3 0.2 0.2 2.9 0.2 0.0 15.9 0.2 0.2 7.3 6.2 0.2 1.2 0.1 2.9 6.0 8.3 1.0 10.0 10.3 0.2 0.2 2.0 0.8 1.1 1.6 0.2 0.2 0.6 0.9 0.5 0.5 0.7 0.3 6.0 6.9 3.0 5.9 1.3 1.2 13.0 5.3 6.2 0.2 0.5 2.4 2.7 0.2 1.0 0.4 7.9 3.9 4.1 2.0 0.3 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 1.7 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.9 1.1 1.1 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.8 0.0 0.8 1.5 0.0 0.3 0.3 0.3 0.9 1.0 0.3 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 CMAS ENSG00000111726 "Cytidine monophosphate N-acetylneuraminic acid synthetase" Q8NFW8 12 22046174-22065674 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039905 Supported Uncertain Nucleoli,Cytosol Cytosol Nucleoli "HPA039905: AB_10795237" "unprognostic (5.54e-2)" "unprognostic (4.10e-2)" "unprognostic (4.25e-1)" "unprognostic (5.39e-3)" "unprognostic (1.94e-2)" "unprognostic (3.99e-2)" "unprognostic (2.30e-2)" "unprognostic (4.17e-3)" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (4.44e-1)" "unprognostic (7.53e-2)" "prognostic unfavourable (7.19e-4)" "unprognostic (2.27e-1)" "unprognostic (1.91e-2)" "unprognostic (3.65e-1)" "unprognostic (2.03e-1)" 8.1 28.2 28.1 9.6 31.6 17.6 14.9 16.3 39.3 12.1 34.3 14.5 17.1 29.4 12.8 32.0 33.2 10.0 11.0 18.1 28.8 33.4 12.8 31.9 7.9 9.8 33.9 27.3 11.9 18.6 14.6 14.3 20.2 34.3 17.0 33.1 10.2 14.8 12.9 18.2 12.9 32.9 13.3 18.0 8.5 12.9 30.2 14.8 6.4 10.9 11.9 12.4 11.8 17.2 12.2 19.5 19.4 18.9 22.8 19.9 15.0 19.5 15.8 19.5 9.2 15.3 19.2 28.4 13.7 15.0 14.9 15.7 35.4 22.7 17.4 13.4 11.7 16.0 11.5 19.0 20.1 22.9 14.4 52.4 12.9 17.8 14.3 13.8 27.8 12.9 18.1 18.9 28.3 19.7 32.9 8.9 26.3 25.8 15.8 32.1 47.1 22.1 11.3 20.4 16.5 17.7 21.5 7.8 13.7 10.8 19.1 15.3 26.3 18.9 14.3 16.8 13.9 14.7 25.1 6.1 7.8 23.1 27.3 10.8 16.9 10.3 17.9 19.4 13.7 18.9 17.8 12.2 18.6 18.1 19.5 12.1 16.8 17.4 1.8 22.8 16.5 12.3 19.9 15.0 28.1 31.6 16.3 39.3 28.8 33.4 33.9 27.3 34.3 14.8 CMPK1 "CMPK, UMP-CMPK" ENSG00000162368 "Cytidine/uridine monophosphate kinase 1" P30085 1 47333797-47378839 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053730, HPA058604" Approved Supported Nucleoplasm "Intracellular and membrane" 2100000 Nucleoplasm "HPA053730: AB_2682244, HPA058604: AB_2683773" "unprognostic (2.16e-2)" "unprognostic (1.16e-1)" "unprognostic (9.39e-3)" "unprognostic (1.18e-1)" "unprognostic (1.09e-3)" "unprognostic (1.50e-2)" "unprognostic (1.59e-2)" "unprognostic (9.88e-2)" "unprognostic (5.80e-2)" "unprognostic (2.90e-2)" "unprognostic (1.71e-2)" "unprognostic (2.61e-1)" "unprognostic (1.28e-2)" "unprognostic (2.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-3)" "unprognostic (7.36e-2)" 35.0 17.0 28.5 30.4 24.4 14.8 72.2 18.0 35.8 26.8 44.8 17.8 20.9 53.7 16.5 19.3 42.2 13.5 39.2 28.6 28.0 31.4 26.2 88.2 36.8 46.2 35.1 16.8 16.2 42.3 19.3 16.6 16.0 25.4 32.8 48.1 16.2 50.8 18.3 30.4 22.2 64.9 46.9 33.1 21.6 35.9 8.6 18.2 25.6 31.7 26.7 28.0 34.0 39.0 11.2 10.6 23.1 12.4 15.0 17.5 12.1 30.3 17.0 22.0 19.7 40.3 47.2 31.3 54.1 32.6 32.9 33.5 15.1 21.1 45.0 27.9 36.7 20.7 16.3 28.0 45.1 68.1 13.3 35.0 23.5 26.1 26.3 49.8 25.6 26.4 33.9 27.4 30.8 34.0 32.9 36.4 42.8 11.1 40.4 23.5 14.0 23.6 25.2 38.2 33.8 32.0 33.5 20.0 10.6 38.7 45.0 31.0 11.2 29.8 31.8 41.2 23.8 39.3 44.4 26.5 36.6 30.7 32.5 30.9 28.1 23.1 10.2 18.2 13.6 10.7 17.5 11.2 15.5 16.7 10.6 10.2 14.7 14.0 4.2 15.0 12.4 8.9 16.0 12.1 28.5 24.4 18.0 35.8 28.0 31.4 35.1 16.8 25.4 18.2 CMPK2 "NDK, TYKi, UMP-CMPK2" ENSG00000134326 "Cytidine/uridine monophosphate kinase 2" Q5EBM0 2 6840570-6866635 "Enzymes, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 13.9;BJ hTERT+ SV40 Large T+ RasG12V: 12.7;HEL: 19.7;MOLT-4: 10.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041430 Approved Approved Mitochondria Mitochondria "HPA041430: AB_10796674" "unprognostic (2.37e-1)" "unprognostic (6.07e-2)" "unprognostic (5.71e-2)" "prognostic unfavourable (4.71e-4)" "unprognostic (1.82e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-2)" "unprognostic (8.93e-2)" "unprognostic (6.63e-2)" "unprognostic (4.54e-3)" "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (1.09e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (7.69e-2)" "unprognostic (4.32e-2)" 8.8 3.8 3.0 6.8 8.1 14.5 4.2 0.9 5.0 2.7 4.2 4.0 1.3 5.0 2.5 6.4 1.8 2.3 3.4 3.7 3.3 3.9 4.0 3.1 17.9 13.4 3.2 5.7 1.3 3.7 2.9 3.0 4.7 3.6 2.1 2.2 4.7 20.8 4.3 3.0 1.2 6.1 3.1 3.8 7.9 7.4 9.2 0.4 8.8 3.1 1.6 2.6 2.7 1.6 1.4 1.9 7.8 6.4 0.9 0.7 1.2 0.2 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.2 13.9 12.7 0.0 1.4 3.1 0.8 0.0 0.2 0.0 0.0 0.0 0.3 0.2 19.7 0.0 0.0 0.0 0.6 1.4 0.0 0.0 0.1 0.0 0.0 4.8 0.1 0.0 0.1 10.8 3.6 0.3 1.0 3.4 0.0 0.0 0.0 0.4 0.3 0.5 0.2 0.0 1.7 0.0 1.3 0.0 0.0 0.2 0.0 0.0 3.3 0.4 0.0 0.0 3.6 0.8 5.5 2.8 7.8 0.7 6.4 0.4 1.4 0.5 0.4 1.9 0.2 0.5 0.5 1.8 0.9 3.2 0.1 0.6 1.2 3.0 8.1 0.9 5.0 3.3 3.9 3.2 5.7 3.6 0.4 CMTR1 "FTSJD2, ISG95, KIAA0082, MTr1" ENSG00000137200 "Cap methyltransferase 1" Q8N1G2 6 37433219-37482827 "Enzymes, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 76.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029954, HPA029979, HPA029980" Enhanced Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA029954: AB_10670558, HPA029979: AB_10671363, HPA029980: AB_10671094" "unprognostic (1.33e-1)" "unprognostic (2.12e-2)" "unprognostic (6.43e-2)" "prognostic unfavourable (1.73e-5)" "unprognostic (1.00e-1)" "unprognostic (3.72e-1)" "unprognostic (1.68e-2)" "unprognostic (6.43e-3)" "unprognostic (2.95e-2)" "unprognostic (9.17e-2)" "unprognostic (5.24e-3)" "unprognostic (1.50e-3)" "unprognostic (3.00e-3)" "unprognostic (3.27e-2)" "unprognostic (9.72e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-2)" 14.4 17.4 23.1 17.3 17.7 22.4 14.6 25.0 25.0 14.5 18.0 15.5 21.3 15.0 19.5 19.4 12.6 16.9 15.0 18.8 17.6 16.1 13.9 16.6 15.2 19.2 16.0 22.7 22.6 18.4 24.4 20.2 20.6 16.9 16.3 13.1 17.1 17.6 17.9 28.9 16.6 16.5 17.6 12.5 21.7 15.9 63.9 17.8 18.4 15.7 14.1 20.7 16.2 14.8 11.1 9.8 8.1 13.2 9.7 11.5 7.8 6.9 6.6 9.5 15.5 10.8 9.9 11.5 8.3 11.5 21.1 23.7 9.9 4.6 14.4 9.4 12.2 7.8 12.1 8.6 16.2 9.9 10.7 7.9 7.7 11.0 8.3 11.4 5.4 8.5 6.4 11.6 8.3 9.8 17.6 10.6 11.0 11.3 14.4 10.2 4.8 6.3 11.5 11.3 8.2 6.8 8.4 10.5 7.9 9.3 7.2 11.9 12.2 8.8 9.0 12.7 9.5 5.0 9.3 12.1 6.3 76.3 5.0 12.0 13.9 8.1 10.2 6.4 10.1 13.2 8.5 11.1 8.9 10.7 9.8 8.1 9.9 8.0 6.6 9.7 9.9 8.2 11.5 7.8 23.1 17.7 25.0 25.0 17.6 16.1 16.0 22.7 16.9 17.8 CMTR2 "AFT, FLJ11171, FTSJD1, MTr2" ENSG00000180917 "Cap methyltransferase 2" Q8IYT2 16 71281389-71289715 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041700, HPA048265" Uncertain Approved "Nuclear speckles,Cell Junctions" "Cell Junctions" "Nuclear speckles" "HPA041700: , HPA048265: " "unprognostic (1.27e-1)" "unprognostic (2.49e-2)" "unprognostic (2.94e-3)" "unprognostic (1.43e-1)" "unprognostic (6.30e-2)" "unprognostic (3.82e-2)" "unprognostic (1.93e-3)" "unprognostic (2.86e-2)" "unprognostic (7.93e-2)" "unprognostic (3.41e-1)" "unprognostic (1.85e-2)" "unprognostic (7.39e-2)" "prognostic favourable (4.97e-5)" "unprognostic (9.55e-2)" "unprognostic (5.99e-2)" "unprognostic (1.54e-1)" "unprognostic (5.34e-2)" 10.4 14.9 7.1 11.7 9.0 5.4 15.9 5.3 9.1 10.6 13.4 11.5 15.6 14.1 12.5 16.4 20.4 8.8 11.0 9.0 8.5 6.9 13.5 18.2 10.7 14.7 12.4 3.4 16.2 12.2 12.7 24.3 17.4 9.0 11.9 10.5 10.6 13.6 14.1 8.4 9.9 16.1 9.4 9.5 17.5 8.9 16.0 9.3 20.9 14.3 7.6 15.4 9.6 14.2 11.2 10.3 11.0 8.0 13.1 11.2 8.6 11.3 7.9 11.4 11.3 12.9 11.2 6.4 9.3 9.1 10.5 10.1 4.7 15.8 6.1 11.2 7.3 11.2 7.0 8.3 12.9 6.3 4.7 17.0 4.6 5.9 16.1 10.0 23.3 8.1 15.9 7.7 10.4 11.9 7.3 4.6 17.4 10.1 12.1 16.9 7.1 4.7 16.4 7.3 13.2 12.9 7.7 7.5 8.5 10.5 9.2 10.2 13.7 7.3 11.4 11.9 11.0 12.1 7.2 8.6 8.9 10.9 8.9 10.2 10.2 11.0 7.2 7.1 9.8 8.0 11.2 11.2 9.2 10.3 10.3 10.2 10.5 10.3 0.4 13.1 5.2 3.6 8.0 8.6 7.1 9.0 5.3 9.1 8.5 6.9 12.4 3.4 9.0 9.3 CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534440-74587212 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 60.3;liver: 41.4" "Cell line enriched" "Detected in single" 69 "U-266/84: 41.2" "Group enriched" "Detected in some" 10 "glioma: 4.4;liver cancer: 1.0;melanoma: 1.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA008933 Enhanced "Secreted in brain" 1900000000 "HPA008933: AB_1847033" "unprognostic (7.43e-3)" "unprognostic (6.00e-2)" "unprognostic (8.55e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (6.90e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" 1.1 1.2 14.9 1.2 28.2 1.3 1.1 4.5 60.3 1.1 1.1 54.9 0.0 5.7 1.1 2.1 1.1 1.1 1.3 1.1 28.9 15.1 1.9 41.4 1.1 1.2 44.1 12.9 1.1 1.2 1.1 0.1 1.1 50.0 1.2 1.1 0.5 1.1 1.3 2.2 1.1 1.9 1.1 51.1 1.1 1.2 1.4 28.8 0.0 1.3 0.0 1.1 1.1 0.0 0.7 0.7 1.9 0.5 1.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 41.2 0.0 0.0 0.0 0.0 1.3 0.5 0.4 0.4 0.2 0.2 0.3 0.3 0.2 0.1 0.7 0.4 0.4 1.9 1.0 0.2 0.7 0.2 0.2 14.9 28.2 4.5 22.5 28.9 15.1 44.1 12.9 50.0 28.8 CNDP2 "CN2, CPGL, FLJ10830, HsT2298, PEPA" ENSG00000133313 "Carnosine dipeptidase 2" Q96KP4 18 74495816-74523454 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 75.1;RPMI-8226: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026196, HPA036898, HPA036899" Enhanced Enhanced Nucleoplasm,Cytosol 2400000 "Nucleoplasm, Cytosol" "CAB026196: , HPA036898: AB_2675370, HPA036899: AB_2675371" "unprognostic (2.81e-2)" "unprognostic (9.96e-2)" "unprognostic (3.28e-1)" "unprognostic (1.19e-3)" "unprognostic (2.57e-2)" "unprognostic (5.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.49e-1)" "unprognostic (9.31e-2)" "unprognostic (1.56e-3)" "unprognostic (1.15e-1)" "prognostic favourable (3.50e-6)" "unprognostic (2.37e-3)" "unprognostic (4.65e-3)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" 19.0 11.5 31.0 19.1 36.0 6.1 16.9 10.4 33.0 39.4 37.6 45.2 27.0 51.3 12.5 35.3 20.4 38.9 25.9 11.6 31.1 26.4 89.0 66.4 22.1 23.0 36.1 24.1 11.4 27.6 15.7 13.7 28.8 27.2 34.7 22.2 14.1 16.9 32.7 7.5 11.8 71.1 10.4 39.4 39.2 27.2 6.5 32.5 10.9 43.9 11.6 21.4 28.4 12.0 29.6 49.0 12.5 44.4 31.4 23.9 30.3 10.0 13.6 9.9 9.3 12.1 7.2 41.6 10.6 10.0 14.5 14.5 7.9 10.8 12.7 13.5 11.5 15.3 15.0 20.1 10.4 19.0 5.9 12.6 6.9 12.5 17.6 24.7 19.7 10.8 15.5 12.5 22.7 12.7 13.3 75.1 9.6 11.3 13.1 11.8 14.9 8.1 14.3 11.4 96.6 57.1 42.2 10.7 5.6 8.3 59.0 14.1 24.7 10.2 13.2 15.6 13.3 3.4 7.1 14.1 57.6 17.0 10.5 18.1 13.0 7.8 30.0 12.5 21.8 44.4 23.8 28.9 17.6 20.3 49.0 29.6 19.1 20.7 4.4 31.4 43.1 43.0 23.9 30.3 31.0 36.0 10.4 33.0 31.1 26.4 36.1 24.1 27.2 32.5 CNOT4 "CLONE243, NOT4, NOT4H" ENSG00000080802 "CCR4-NOT transcription complex subunit 4" O95628 7 135361795-135510127 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005737 Approved "HPA005737: AB_1078544" "unprognostic (9.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "unprognostic (5.47e-2)" "unprognostic (3.61e-1)" "unprognostic (1.64e-2)" "prognostic unfavourable (1.19e-4)" "unprognostic (2.82e-2)" "unprognostic (4.18e-2)" "prognostic favourable (1.61e-4)" "unprognostic (9.08e-2)" "unprognostic (1.00e-2)" "prognostic favourable (7.67e-6)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (2.23e-1)" "unprognostic (9.33e-2)" 19.4 14.3 19.8 12.0 23.3 11.1 13.8 31.6 24.6 18.7 15.0 21.9 7.0 11.3 21.1 15.2 15.8 16.7 13.8 18.7 19.2 18.0 16.0 16.0 13.6 14.4 18.5 15.1 24.7 14.1 22.6 28.6 16.1 21.1 15.3 13.4 16.4 16.8 15.6 35.0 15.6 12.3 17.1 22.6 13.7 12.3 25.8 18.5 18.5 21.1 12.3 18.1 16.2 15.7 12.0 10.0 21.5 12.7 16.7 15.5 9.1 13.5 12.9 13.2 17.6 22.0 17.5 9.6 15.3 16.7 13.1 16.3 11.1 14.0 13.6 13.3 13.9 13.0 16.7 11.6 18.8 15.3 12.8 11.2 11.1 9.8 12.3 12.5 13.4 13.4 14.8 16.7 10.5 13.4 19.5 10.9 19.1 17.0 17.2 20.5 17.3 10.9 11.2 13.0 14.7 15.4 12.6 14.0 16.5 17.8 20.1 11.1 12.4 14.3 18.0 15.9 9.5 14.7 16.5 16.8 15.7 19.4 16.0 14.8 21.1 21.5 11.5 14.9 14.1 11.5 15.5 11.0 12.0 11.7 10.0 12.0 13.1 12.1 10.7 16.7 12.7 8.0 10.1 9.1 19.8 23.3 31.6 24.6 19.2 18.0 18.5 15.1 21.1 18.5 CNOT6 "CCR4, Ccr4a, KIAA1194" ENSG00000113300 "CCR4-NOT transcription complex subunit 6" Q9ULM6 5 180494412-180578405 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Activator, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044568 Approved Approved Cytosol Cytosol "HPA044568: AB_10797257" "unprognostic (9.41e-3)" "unprognostic (1.40e-1)" "unprognostic (2.03e-3)" "unprognostic (2.55e-1)" "unprognostic (1.41e-1)" "unprognostic (2.59e-1)" "prognostic unfavourable (3.61e-7)" "unprognostic (1.31e-1)" "unprognostic (1.10e-2)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-1)" "unprognostic (4.03e-2)" "unprognostic (3.57e-2)" 10.2 10.1 19.2 15.4 20.2 14.4 13.3 43.9 18.7 12.0 16.4 11.7 9.7 16.2 13.1 12.4 19.6 13.3 12.7 13.0 15.9 11.1 14.1 8.6 13.0 14.3 12.3 14.0 14.8 10.3 13.4 12.7 17.6 12.9 13.9 16.2 14.3 13.4 10.9 8.3 14.4 20.6 13.4 12.3 17.0 13.7 17.6 14.9 25.1 12.6 10.0 18.4 16.9 24.5 2.2 2.5 3.4 5.8 2.1 4.5 1.7 10.8 13.1 27.0 21.5 4.5 5.2 27.9 8.0 5.4 10.6 12.7 16.0 16.0 11.5 12.2 5.2 11.5 22.5 26.6 12.5 33.7 11.3 12.5 17.7 10.2 6.7 14.6 9.2 4.3 12.9 7.8 16.7 12.9 13.3 11.1 9.8 22.4 18.5 8.8 7.9 6.3 17.1 13.6 8.2 11.7 21.6 19.8 16.7 13.5 18.1 11.5 22.6 14.8 14.0 11.4 13.1 8.2 14.1 7.3 13.0 12.2 10.8 20.1 9.3 1.5 2.6 3.4 3.8 4.1 4.0 2.0 3.3 2.3 2.4 2.2 4.5 4.4 2.2 2.1 5.8 2.5 2.3 1.7 19.2 20.2 43.9 18.7 15.9 11.1 12.3 14.0 12.9 14.9 CNOT6L "Ccr4b, DKFZp434K098" ENSG00000138767 "CCR4-NOT transcription complex subunit 6 like" Q96LI5 4 77713387-77819615 "Enzymes, Predicted intracellular proteins" "mRNA processing, RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 51.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042688 Uncertain Supported Cytosol Cytosol "HPA042688: AB_10794384" "unprognostic (3.91e-1)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.10e-2)" "unprognostic (2.56e-1)" "unprognostic (3.72e-2)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (5.06e-2)" "unprognostic (6.86e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic favourable (1.69e-4)" "unprognostic (4.51e-2)" "unprognostic (7.95e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-3)" 13.6 7.8 8.6 21.5 8.2 15.3 11.0 11.1 9.2 7.8 7.3 7.0 4.6 7.5 11.4 6.3 10.2 7.1 8.3 7.5 6.0 5.7 7.7 10.8 12.7 19.2 7.6 7.3 8.8 10.8 14.6 10.0 12.3 6.7 8.4 8.9 10.3 9.9 7.4 9.1 12.2 11.5 8.4 6.9 23.4 7.9 7.3 5.6 51.3 9.1 6.2 21.1 10.7 10.3 7.5 6.1 20.2 9.3 7.4 10.0 4.4 8.6 5.6 7.1 4.7 8.4 7.3 7.0 6.9 9.1 6.2 8.4 2.2 9.7 15.0 8.8 9.6 5.6 9.1 9.6 8.3 15.0 5.1 14.0 7.8 6.3 5.3 13.9 12.3 4.7 12.4 6.9 12.8 19.6 11.7 20.1 7.1 5.9 25.7 7.0 3.2 1.8 6.3 20.0 10.7 7.1 9.8 8.7 4.2 11.9 10.9 4.8 3.5 7.2 21.3 6.0 6.6 11.3 3.8 25.8 11.0 18.7 6.5 6.1 4.4 20.2 4.7 10.2 10.0 7.0 10.0 5.3 7.5 7.8 4.5 7.5 7.3 8.5 6.7 7.4 9.3 6.1 6.0 4.4 8.6 8.2 11.1 9.2 6.0 5.7 7.6 7.3 6.7 5.6 CNOT7 CAF1 ENSG00000198791 "CCR4-NOT transcription complex subunit 7" Q9UIV1 8 17224964-17246878 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069543 Supported "Nuclear bodies" "Nuclear bodies" "HPA069543: " "unprognostic (1.55e-1)" "unprognostic (4.49e-2)" "prognostic favourable (4.99e-4)" "unprognostic (4.61e-2)" "unprognostic (8.45e-2)" "unprognostic (3.10e-2)" "unprognostic (1.44e-3)" "unprognostic (4.54e-2)" "unprognostic (6.83e-2)" "unprognostic (4.09e-3)" "unprognostic (2.51e-1)" "unprognostic (1.74e-1)" "unprognostic (3.49e-2)" "unprognostic (1.72e-1)" "unprognostic (4.51e-1)" "unprognostic (2.24e-1)" "unprognostic (2.52e-1)" 18.3 25.8 28.7 23.8 37.0 24.2 23.3 34.6 31.8 17.5 22.8 15.9 19.8 20.8 22.2 26.1 24.5 20.6 19.8 21.4 22.3 29.3 28.2 36.8 17.9 32.0 22.3 22.5 25.9 28.0 40.4 29.7 25.0 23.1 19.3 24.6 18.2 32.3 22.4 43.2 18.5 22.7 20.6 19.8 27.6 19.0 26.9 22.4 60.6 33.6 19.6 34.3 25.5 19.4 57.8 49.9 46.6 50.7 45.2 67.0 52.2 20.6 25.6 38.6 28.6 16.3 17.2 26.7 26.7 22.8 31.0 27.6 29.9 16.6 28.6 29.4 23.3 16.6 40.6 33.6 45.3 11.8 19.5 37.6 19.8 32.2 21.0 25.2 23.3 16.4 28.0 26.4 28.3 36.9 31.4 31.9 31.2 16.2 61.9 23.6 42.5 19.6 33.8 28.7 21.5 27.0 45.6 48.7 32.6 18.8 16.8 30.4 20.1 21.5 24.6 23.2 32.9 25.8 29.9 16.6 52.8 50.1 21.7 24.1 22.8 46.3 43.3 46.6 38.1 50.7 45.3 57.8 52.9 45.2 49.9 57.1 67.0 52.7 37.9 45.2 43.5 44.9 57.5 52.2 28.7 37.0 34.6 31.8 22.3 29.3 22.3 22.5 23.1 22.4 CNOT8 "CAF1, CALIF, hCAF1, POP2" ENSG00000155508 "CCR4-NOT transcription complex subunit 8" Q9UFF9 5 154857553-154876793 "Enzymes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051398 Approved "HPA051398: " "unprognostic (2.51e-1)" "unprognostic (4.26e-1)" "unprognostic (1.69e-2)" "unprognostic (1.48e-1)" "unprognostic (1.68e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.33e-4)" "unprognostic (1.19e-1)" "unprognostic (3.62e-2)" "unprognostic (2.35e-2)" "unprognostic (1.79e-2)" "unprognostic (2.80e-1)" "unprognostic (3.32e-3)" "unprognostic (2.19e-1)" "unprognostic (1.84e-1)" "unprognostic (3.66e-2)" "prognostic favourable (6.41e-4)" 40.5 28.0 23.6 20.9 23.8 60.1 30.3 20.3 29.2 26.0 23.5 21.3 19.5 19.0 21.1 22.5 18.2 18.2 17.5 17.2 23.2 16.1 17.1 16.6 33.5 30.5 33.0 18.3 20.0 16.2 20.1 17.8 23.9 24.4 17.4 27.5 16.5 24.1 17.5 14.3 28.0 23.7 23.2 25.9 30.7 19.1 24.4 26.2 41.5 36.0 11.3 29.5 24.6 22.8 20.5 33.4 65.4 31.9 20.9 31.5 36.6 12.0 13.9 24.2 26.6 23.2 21.2 18.4 18.6 20.7 20.5 31.9 17.8 27.0 21.2 23.5 15.9 13.3 16.7 23.1 23.4 10.5 17.3 17.7 21.6 15.7 14.7 40.7 33.0 14.4 20.3 18.3 15.9 25.2 15.6 16.0 21.4 14.4 35.9 42.6 13.1 8.2 30.2 20.5 22.0 16.2 16.7 19.0 28.4 24.9 20.1 23.1 18.8 33.5 19.5 21.8 13.7 11.9 12.2 15.5 19.9 32.6 15.3 32.5 13.5 55.0 31.9 65.4 19.3 22.6 21.4 20.5 24.0 23.1 33.4 20.4 31.5 22.7 32.2 20.9 17.7 18.0 26.0 36.6 23.6 23.8 20.3 29.2 23.2 16.1 33.0 18.3 24.4 26.2 CNP ENSG00000173786 "2',3'-cyclic nucleotide 3' phosphodiesterase" P09543 17 41966741-41977731 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 211.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 49.1" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002672, HPA023266, HPA023278, HPA023280, HPA023338" Enhanced Supported Enhanced Nucleoplasm,Cytosol 730000 Nucleoplasm Cytosol "CAB002672: , HPA023266: AB_1847058, HPA023278: AB_1847060, HPA023280: AB_1847061, HPA023338: AB_1847062" "unprognostic (2.17e-1)" "unprognostic (4.48e-2)" "unprognostic (3.85e-3)" "unprognostic (1.41e-1)" "unprognostic (3.09e-1)" "unprognostic (9.71e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.87e-1)" "unprognostic (2.99e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.10e-3)" 9.1 8.9 51.4 9.5 72.8 6.7 8.1 13.4 125.3 10.3 7.5 211.7 2.3 7.1 8.0 12.7 15.0 9.3 10.8 7.6 78.4 40.7 14.7 9.6 6.7 10.5 86.7 49.0 11.2 9.2 5.8 4.4 7.8 66.7 11.7 6.4 3.6 15.1 13.2 7.6 11.1 6.4 10.1 160.2 7.1 7.4 4.6 63.5 2.1 7.2 2.2 11.2 9.8 5.7 9.9 49.1 7.3 13.1 7.3 7.5 9.1 13.7 23.5 22.3 27.5 19.1 18.0 9.6 17.2 26.5 44.8 50.6 18.4 12.6 14.6 13.9 22.4 23.7 15.0 11.4 15.6 14.5 19.0 14.2 16.2 31.9 20.6 13.8 12.9 29.7 8.2 24.5 6.0 20.4 10.0 12.0 15.6 8.7 35.4 12.5 5.2 16.8 22.1 32.8 14.2 11.9 14.1 13.1 17.7 21.8 32.9 38.3 14.7 20.7 20.4 17.5 19.2 23.7 20.3 13.5 15.3 11.7 17.3 10.7 68.2 4.9 12.1 7.3 7.5 13.1 5.9 9.9 6.5 6.0 11.1 7.0 5.9 6.9 2.6 7.3 10.3 49.1 7.2 9.1 51.4 72.8 13.4 93.8 78.4 40.7 86.7 49.0 66.7 63.5 COASY "CoASY, DPCK, NBP, PPAT" ENSG00000068120 "Coenzyme A synthase" Q13057 17 42561467-42566277 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022875, HPA022912, HPA023273" Approved "Intracellular and membrane" 10000 "HPA022875: AB_1847066, HPA022912: AB_1847067, HPA023273: AB_1847068" "unprognostic (2.83e-1)" "unprognostic (8.35e-2)" "unprognostic (1.81e-1)" "prognostic favourable (2.15e-4)" "unprognostic (1.01e-1)" "unprognostic (5.72e-2)" "prognostic unfavourable (7.54e-5)" "unprognostic (4.06e-2)" "unprognostic (3.36e-2)" "unprognostic (2.50e-2)" "unprognostic (1.50e-1)" "unprognostic (7.83e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (5.55e-1)" "unprognostic (1.62e-1)" "unprognostic (2.16e-1)" 15.4 28.3 14.6 15.5 16.9 18.1 20.6 19.4 25.9 16.9 22.8 16.7 31.9 30.2 17.7 17.0 32.7 21.4 20.4 12.7 14.6 10.2 40.6 66.0 20.7 15.6 14.1 15.1 18.7 33.9 27.2 19.3 18.0 20.5 20.9 18.5 14.5 43.2 36.6 21.2 25.1 32.1 12.3 14.4 27.1 24.7 25.7 14.6 21.5 30.2 22.7 20.9 16.3 18.2 14.6 28.5 21.2 26.2 16.3 18.8 18.0 28.4 46.3 8.6 17.3 19.1 11.1 28.2 12.0 17.2 21.3 15.2 26.5 28.0 16.3 21.4 15.5 45.0 22.7 26.0 14.3 14.8 39.5 16.4 29.6 42.0 22.9 17.1 23.1 17.1 31.3 21.0 22.3 20.1 30.3 22.0 15.1 17.5 21.6 26.0 11.7 23.7 12.2 29.7 26.7 28.8 20.4 20.7 15.7 11.7 11.9 22.7 49.4 21.7 12.6 21.8 20.2 16.9 12.9 26.6 37.0 9.3 25.3 17.0 15.0 15.3 24.5 21.2 18.2 26.2 18.8 14.5 14.5 17.2 28.5 14.6 14.1 14.5 16.7 16.3 17.8 19.4 15.3 18.0 14.6 16.9 19.4 25.9 14.6 10.2 14.1 15.1 20.5 14.6 COLGALT1 "FLJ22329, GLT25D1" ENSG00000130309 "Collagen beta(1-O)galactosyltransferase 1" Q8NBJ5 19 17555594-17583162 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047821 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA047821: " "unprognostic (2.46e-1)" "unprognostic (1.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "prognostic unfavourable (1.65e-5)" "unprognostic (2.92e-3)" "unprognostic (2.92e-1)" "unprognostic (1.66e-3)" "prognostic unfavourable (1.92e-4)" "unprognostic (3.89e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.43e-2)" "unprognostic (1.09e-1)" "unprognostic (8.87e-2)" "prognostic unfavourable (3.83e-4)" 29.8 11.4 12.1 26.9 16.5 21.3 36.2 15.6 13.1 18.2 18.5 10.8 9.6 12.0 21.9 20.2 17.6 19.2 18.1 21.7 10.8 7.1 11.1 17.8 25.1 46.1 19.4 7.3 19.0 15.2 7.9 8.1 29.6 11.8 12.6 11.6 9.5 12.0 13.0 10.7 16.7 17.3 25.7 11.3 30.9 13.9 11.2 17.9 10.3 11.3 12.7 11.9 19.6 19.1 2.5 11.5 7.6 17.4 1.4 3.6 7.1 23.0 27.3 13.3 18.3 52.7 32.8 21.2 21.6 12.7 28.5 29.7 20.6 36.4 11.8 38.8 37.9 20.6 13.5 25.1 17.4 6.7 21.7 11.3 35.5 19.5 28.9 27.0 34.6 27.1 22.5 32.0 13.4 32.0 23.1 6.0 10.3 10.2 13.6 17.5 9.8 26.6 14.5 17.0 18.0 6.0 15.3 9.6 7.0 23.2 18.5 21.9 9.6 39.4 22.3 56.8 16.1 50.3 35.1 10.7 27.1 13.0 33.5 51.5 25.7 1.1 15.0 7.6 3.4 17.4 2.0 2.3 3.2 3.2 11.5 2.5 2.3 3.6 2.4 1.4 12.6 4.4 1.9 7.1 12.1 16.5 15.6 13.1 10.8 7.1 19.4 7.3 11.8 17.9 COLGALT2 "C1orf17, GLT25D2, KIAA0584" ENSG00000198756 "Collagen beta(1-O)galactosyltransferase 2" Q8IYK4 1 183929854-184037729 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.0" "Cell line enhanced" "Detected in many" "Hep G2: 12.7;SK-MEL-30: 13.7;U-251 MG: 13.1;WM-115: 17.0" "Cancer enhanced" "Detected in many" "glioma: 11.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 11 "basophil: 8.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 8.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031749, HPA031750" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" Nucleoplasm Vesicles "HPA031749: AB_10599298, HPA031750: AB_10611252" "unprognostic (5.44e-3)" "unprognostic (3.08e-1)" "unprognostic (6.29e-5)" "unprognostic (2.08e-1)" "unprognostic (4.41e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (2.52e-1)" "unprognostic (2.00e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (5.13e-9)" "unprognostic (1.53e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (3.80e-2)" 2.1 9.4 10.8 1.7 16.6 1.9 2.8 10.6 39.0 2.0 3.0 31.3 0.0 1.4 3.0 5.2 1.7 3.5 3.7 11.7 15.3 7.9 1.8 1.0 4.5 1.1 20.2 12.9 2.3 3.5 1.0 1.9 0.8 17.4 8.1 2.0 3.5 4.4 3.7 11.0 1.1 1.4 3.0 21.8 1.3 3.4 5.0 22.5 0.0 5.1 1.8 1.5 2.4 1.4 0.0 0.0 8.1 0.0 0.7 0.6 0.1 0.1 0.0 4.4 0.2 2.3 3.4 0.1 1.2 0.5 0.6 0.7 2.1 0.2 0.0 0.3 3.3 0.0 4.2 0.0 1.1 4.6 2.3 0.3 0.0 12.7 0.1 4.1 0.0 2.0 0.0 0.6 0.1 0.0 4.1 5.4 4.6 0.1 0.2 0.2 3.0 0.0 0.4 0.0 0.0 0.0 0.9 1.7 2.7 0.2 0.0 13.7 0.0 0.2 0.0 0.5 0.4 0.0 13.1 8.0 0.0 0.0 0.4 2.0 17.0 8.1 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.1 10.8 16.6 10.6 17.2 15.3 7.9 20.2 12.9 17.4 22.5 COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941607-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 139.3" "Cell line enhanced" "Detected in many" "MCF7: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Supported "Endoplasmic reticulum,Vesicles" 560000 Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: AB_1078402" "unprognostic (5.20e-2)" "unprognostic (2.73e-2)" "unprognostic (3.08e-2)" "prognostic favourable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (2.32e-3)" "unprognostic (5.54e-3)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-3)" "prognostic favourable (5.67e-4)" "prognostic unfavourable (9.76e-4)" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.07e-2)" 18.6 49.0 29.4 14.3 28.8 24.3 27.8 19.6 32.9 22.4 23.4 42.4 36.1 21.0 19.8 33.8 58.1 19.4 36.8 28.1 28.9 22.3 31.1 139.3 30.9 17.0 29.0 18.4 36.3 27.2 14.1 12.7 59.0 23.3 25.7 8.9 24.9 67.3 30.9 21.5 27.7 28.6 15.5 41.0 17.8 24.8 18.2 23.7 11.5 19.2 44.0 32.0 36.3 28.0 11.2 55.1 10.9 60.0 12.9 15.6 28.0 19.0 19.6 2.2 19.4 22.1 19.7 0.8 21.6 27.3 18.5 21.3 16.6 22.2 7.7 9.6 30.9 26.1 3.7 23.2 4.9 16.6 24.7 13.7 10.5 38.7 41.3 22.8 5.5 25.0 28.7 16.1 16.0 17.4 55.4 16.4 15.0 118.0 8.9 41.0 4.8 6.6 13.5 19.4 10.6 19.6 60.5 9.5 8.3 7.2 61.3 17.8 13.2 64.3 20.8 33.2 12.7 10.9 16.2 6.0 2.5 6.3 35.8 30.9 22.8 10.2 60.0 10.9 15.6 39.9 12.8 11.2 10.8 12.6 47.7 10.7 9.6 10.6 2.4 12.9 26.6 55.1 13.3 28.0 29.4 28.8 19.6 32.9 28.9 22.3 29.0 18.4 23.3 23.7 COPS5 "CSN5, JAB1, MOV-34, SGN5" ENSG00000121022 "COP9 signalosome subunit 5" Q92905 8 67043079-67083783 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004242, HPA004845, HPA051531" Supported Enhanced Nucleoplasm 27000 Nucleoplasm "CAB004242: AB_627835, HPA004845: AB_1078557, HPA051531: " "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (1.61e-1)" "unprognostic (2.85e-3)" "unprognostic (2.53e-1)" "unprognostic (4.16e-2)" "unprognostic (2.04e-3)" "unprognostic (1.39e-1)" "unprognostic (2.15e-2)" "unprognostic (4.48e-2)" "unprognostic (4.74e-3)" "unprognostic (1.96e-2)" "unprognostic (1.90e-3)" "unprognostic (2.88e-2)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-2)" 20.2 26.3 29.4 19.6 28.6 16.2 28.1 28.5 40.3 18.0 21.7 15.6 20.2 22.0 17.6 21.7 24.0 17.7 15.5 46.8 27.6 27.5 27.4 33.7 16.8 17.5 31.8 29.9 17.0 20.7 23.3 21.7 24.3 33.7 18.3 25.5 9.9 19.6 18.9 64.0 16.8 22.5 23.3 39.2 16.1 20.7 27.4 31.3 19.6 18.5 29.2 22.4 18.3 16.5 20.7 35.1 33.7 30.0 26.5 28.1 22.3 30.2 28.7 24.4 22.3 25.7 27.4 19.4 26.7 21.9 37.1 33.4 18.6 37.3 28.1 12.3 27.5 25.3 32.7 29.4 40.9 26.9 28.2 39.9 28.9 24.9 24.9 25.2 24.3 24.9 37.7 30.2 39.0 36.1 47.2 19.5 33.2 28.1 44.3 44.2 32.4 33.1 28.5 17.5 22.1 39.2 27.0 14.8 20.4 15.3 29.7 25.8 48.8 26.0 26.7 18.8 23.3 22.7 20.8 24.6 31.3 37.4 27.5 28.7 25.6 26.0 28.6 33.7 20.8 30.0 21.7 20.7 20.1 23.1 35.1 17.5 21.6 19.1 21.2 26.5 28.3 18.4 28.1 22.3 29.4 28.6 28.5 40.3 27.6 27.5 31.8 29.9 33.7 31.3 COPS6 "CSN6, MOV34-34KD" ENSG00000168090 "COP9 signalosome subunit 6" Q7L5N1 7 100088954-100092200 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044315 Approved Supported Nucleoplasm "Intracellular and membrane" 58000 Nucleoplasm "HPA044315: AB_10959750" "unprognostic (1.48e-2)" "unprognostic (2.43e-2)" "unprognostic (6.56e-3)" "unprognostic (1.38e-1)" "unprognostic (5.84e-2)" "unprognostic (2.09e-2)" "unprognostic (3.62e-3)" "unprognostic (2.93e-2)" "unprognostic (2.00e-1)" "unprognostic (2.45e-2)" "unprognostic (4.96e-2)" "unprognostic (1.25e-1)" "prognostic unfavourable (6.72e-4)" "unprognostic (1.20e-1)" "unprognostic (3.58e-2)" "unprognostic (8.57e-2)" "unprognostic (8.77e-2)" 25.4 30.0 37.7 20.2 50.6 19.7 25.6 31.5 43.3 32.5 30.4 26.5 15.1 19.3 31.0 39.8 33.4 33.7 32.4 47.2 31.5 32.1 31.7 41.2 20.1 30.4 33.3 32.6 30.8 42.8 38.1 28.2 29.1 34.1 27.4 26.6 25.0 28.3 35.7 53.1 23.4 19.2 45.2 30.1 22.7 26.9 25.5 30.8 29.4 27.6 21.6 25.8 26.7 24.8 53.4 67.6 58.9 64.0 48.2 69.4 45.3 31.8 45.4 27.3 32.3 24.0 28.7 17.3 29.0 44.6 48.6 35.7 37.1 30.2 22.1 37.5 47.4 24.4 30.8 49.0 49.2 21.9 48.3 18.8 45.1 28.6 50.3 21.3 19.5 28.3 32.5 52.2 55.9 66.3 26.9 31.9 57.1 79.3 47.1 31.7 24.6 54.6 22.5 45.4 52.6 38.5 30.0 42.8 31.8 29.9 59.2 21.9 24.4 21.1 34.8 46.8 42.7 56.0 50.9 23.6 26.1 45.2 35.4 29.0 69.0 58.9 61.9 51.7 61.1 64.0 61.2 53.4 61.3 57.8 67.6 49.8 48.3 53.9 24.1 48.2 57.4 50.2 69.4 45.3 37.7 50.6 31.5 43.3 31.5 32.1 33.3 32.6 34.1 30.8 COQ2 "CL640, FLJ26072" ENSG00000173085 "Coenzyme Q2, polyprenyltransferase" Q96H96 4 83261536-83284914 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease mutation, Neurodegeneration, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056599, HPA068727" Approved Approved Cytosol Cytosol "HPA056599: AB_2683184, HPA068727: AB_2686022" "unprognostic (8.26e-2)" "unprognostic (7.40e-3)" "unprognostic (3.95e-3)" "unprognostic (1.55e-1)" "unprognostic (9.22e-2)" "unprognostic (5.59e-2)" "unprognostic (1.26e-2)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.56e-2)" "unprognostic (3.73e-1)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (2.46e-1)" 6.6 25.5 4.9 8.4 7.0 8.9 9.9 1.9 6.0 7.4 12.1 5.8 8.4 7.8 8.0 10.2 13.1 5.4 7.4 17.5 4.3 4.1 8.0 14.9 9.8 9.0 6.5 3.4 8.0 5.9 6.7 12.3 7.2 5.0 6.6 12.5 5.2 12.7 8.5 21.8 13.8 8.2 5.8 6.7 14.1 4.8 6.6 6.7 2.9 10.1 23.9 9.2 6.2 7.4 3.6 11.8 6.0 17.4 3.7 2.0 6.8 11.6 6.8 6.8 12.8 5.3 5.4 4.8 7.6 12.5 14.4 16.8 4.7 16.8 7.9 5.5 13.4 9.0 11.4 12.3 18.1 8.0 7.2 7.0 8.9 6.7 5.7 14.2 33.9 8.0 7.8 6.9 12.0 14.3 4.5 9.4 13.3 12.0 3.7 9.6 5.0 9.7 6.5 5.3 10.2 20.9 5.6 4.7 3.1 8.7 11.0 3.8 7.1 7.8 9.9 6.7 7.0 5.1 10.5 2.8 2.2 4.6 13.2 16.8 9.2 1.1 16.3 2.3 1.6 14.4 1.2 3.6 1.8 1.5 11.8 3.5 1.3 2.0 6.0 3.7 17.4 6.2 2.0 6.8 4.9 7.0 1.9 6.0 4.3 4.1 6.5 3.4 5.0 6.7 COQ3 bA9819.1 ENSG00000132423 "Coenzyme Q3, methyltransferase" Q9NZJ6 6 99369400-99394204 "Enzymes, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031273, HPA031274" Enhanced Approved Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA031273: AB_10611107, HPA031274: AB_10602176" "unprognostic (1.81e-2)" "unprognostic (2.69e-2)" "unprognostic (1.45e-2)" "unprognostic (4.62e-2)" "unprognostic (2.41e-2)" "unprognostic (2.16e-2)" "unprognostic (1.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.40e-1)" "unprognostic (8.77e-2)" "unprognostic (9.78e-2)" "unprognostic (1.09e-1)" "prognostic favourable (6.86e-5)" "unprognostic (4.61e-2)" "unprognostic (1.81e-1)" "unprognostic (5.45e-2)" "unprognostic (1.08e-1)" 5.2 7.8 8.6 4.2 10.8 3.2 7.5 13.6 16.3 4.5 8.9 4.5 4.3 6.9 4.3 6.8 8.2 4.5 3.0 21.7 8.2 7.5 10.2 12.4 2.9 7.1 6.9 12.0 6.0 5.7 11.6 7.4 2.5 9.8 6.8 11.0 7.3 11.7 7.6 28.0 5.8 6.3 6.6 4.6 4.8 5.2 2.3 6.0 4.1 4.3 16.8 7.0 7.5 4.6 6.6 8.0 9.4 7.4 9.7 12.5 5.3 11.9 6.9 8.4 11.8 5.4 6.1 11.5 10.4 6.4 15.7 18.2 9.6 5.2 11.8 6.9 7.7 11.2 13.9 16.2 19.2 12.4 17.8 14.3 9.4 10.2 7.2 20.6 5.6 3.9 9.9 9.2 9.4 9.5 21.7 8.9 8.3 11.9 9.0 17.3 10.1 13.3 4.4 8.6 15.6 12.3 10.5 13.1 7.0 7.2 11.1 13.5 13.6 13.7 3.4 6.9 10.1 10.5 15.7 3.1 5.8 18.4 8.8 20.1 10.1 9.4 3.3 2.4 6.0 7.4 6.8 6.6 7.6 9.5 8.0 3.1 12.5 9.5 0.5 9.7 6.3 5.2 5.5 5.3 8.6 10.8 13.6 16.3 8.2 7.5 6.9 12.0 9.8 6.0 COQ5 MGC4767 ENSG00000110871 "Coenzyme Q5, methyltransferase" Q5HYK3 12 120503274-120534434 "Enzymes, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049487 Approved Uncertain Nucleoli,Mitochondria Nucleoli Mitochondria "HPA049487: " "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-1)" "unprognostic (6.30e-3)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (1.60e-1)" "unprognostic (2.01e-2)" "unprognostic (6.20e-2)" "unprognostic (1.62e-1)" "unprognostic (8.37e-2)" "unprognostic (3.79e-2)" "unprognostic (2.02e-1)" "unprognostic (7.73e-2)" "unprognostic (2.00e-2)" "unprognostic (3.88e-2)" 14.6 21.7 15.8 16.1 16.7 7.0 29.5 15.6 21.3 12.5 16.4 13.5 21.8 15.7 12.6 16.4 14.0 15.5 13.5 31.9 14.8 13.1 26.0 39.8 17.6 19.1 17.5 15.4 15.1 28.6 14.2 13.4 18.6 19.4 12.7 17.1 11.6 17.9 17.8 58.4 11.1 13.2 14.0 18.5 14.6 12.4 16.9 15.0 17.2 17.7 30.4 15.2 10.1 17.0 21.3 27.4 9.7 19.6 25.1 28.2 22.4 16.3 26.2 23.7 6.8 31.2 24.1 16.3 20.0 13.1 20.5 13.0 10.5 13.8 16.5 23.7 20.9 17.7 21.0 22.2 21.1 20.6 12.4 22.0 16.1 17.3 25.6 23.9 13.8 23.0 24.1 19.1 22.5 18.0 21.5 12.1 23.6 21.5 13.8 27.5 20.8 20.4 25.6 24.0 23.9 26.4 12.5 17.9 14.4 14.5 7.4 27.2 37.2 19.7 17.9 14.2 16.3 10.5 13.2 26.2 22.0 18.8 16.2 22.7 17.0 9.4 19.6 9.7 18.8 19.2 18.2 21.1 20.4 19.9 27.4 21.3 28.2 22.3 2.1 25.1 17.9 18.0 24.4 22.4 15.8 16.7 15.6 21.3 14.8 13.1 17.5 15.4 19.4 15.0 COQ8A "ADCK3, CABC1, COQ8, SCAR9" ENSG00000163050 "Coenzyme Q8A" Q8NI60 1 226897536-226987545 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Kinase, Transferase" "Disease mutation, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 216.5" "Cell line enhanced" "Detected in many" "HEK 293: 33.0;RPMI-8226: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061662 Supported Mitochondria Mitochondria "HPA061662: " "unprognostic (6.37e-3)" "unprognostic (2.09e-2)" "unprognostic (2.29e-1)" "unprognostic (9.06e-2)" "unprognostic (8.94e-2)" "unprognostic (2.49e-1)" "unprognostic (4.42e-2)" "unprognostic (3.50e-3)" "unprognostic (1.81e-1)" "unprognostic (4.02e-1)" "unprognostic (4.15e-3)" "unprognostic (8.67e-2)" "unprognostic (2.40e-2)" "unprognostic (9.24e-2)" "unprognostic (2.82e-1)" "unprognostic (8.88e-2)" "unprognostic (2.62e-1)" 13.3 25.4 2.8 2.7 4.5 5.3 8.5 14.5 3.9 3.2 7.3 4.1 4.2 6.9 3.6 5.5 7.3 5.0 6.1 41.0 2.7 1.8 3.8 17.7 2.7 4.1 5.0 2.4 7.2 20.3 1.6 1.6 2.0 3.8 6.5 2.0 1.9 7.2 5.0 216.5 4.4 4.4 7.8 2.9 3.5 8.8 3.0 4.7 2.7 4.6 50.2 5.8 10.2 3.5 15.2 9.3 32.3 11.5 9.9 11.8 11.6 3.2 5.8 1.5 4.5 4.7 3.1 23.6 1.5 1.3 2.2 2.9 9.2 5.2 9.5 7.3 1.0 3.7 2.9 3.3 0.5 9.9 33.0 6.6 4.8 15.1 1.0 10.0 4.1 5.9 5.1 1.7 2.3 1.0 11.4 7.8 0.3 4.3 5.8 14.7 6.4 12.0 5.7 7.1 30.2 0.7 2.4 24.3 9.9 3.0 11.8 8.5 6.2 13.6 1.2 2.5 2.3 3.5 5.5 17.6 15.4 5.0 2.3 11.4 2.4 19.7 11.5 32.3 8.7 8.6 8.3 12.1 8.5 7.7 9.3 15.2 11.8 9.0 21.9 9.9 6.5 4.1 10.6 11.6 2.8 4.5 14.5 3.9 2.7 1.8 5.0 2.4 3.8 4.7 COQ8B "ADCK4, COQ8, FLJ12229" ENSG00000123815 "Coenzyme Q8B" Q96D53 19 40691529-40718207 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027229, HPA027277, HPA027279, HPA028303" Supported Enhanced Mitochondria Mitochondria "HPA027229: AB_10600100, HPA027277: AB_10599857, HPA027279: AB_10601219, HPA028303: AB_2672551" "unprognostic (7.57e-2)" "unprognostic (9.48e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-2)" "unprognostic (2.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.85e-1)" "unprognostic (2.27e-1)" "unprognostic (2.82e-2)" "unprognostic (1.48e-1)" "unprognostic (2.93e-2)" "unprognostic (6.18e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (2.65e-2)" 13.6 17.8 21.1 13.1 16.4 11.5 10.0 24.1 19.2 13.6 13.6 18.6 14.8 17.9 15.0 13.2 16.6 26.5 16.7 14.7 15.7 10.7 11.8 15.6 12.1 12.2 15.5 12.1 16.3 19.4 12.6 32.7 7.9 13.2 15.1 5.7 12.3 16.8 17.6 10.3 12.9 18.6 16.2 15.6 12.1 17.5 12.5 16.7 16.8 15.5 6.9 13.2 14.8 11.8 12.9 15.0 17.7 15.6 9.7 13.1 10.5 8.2 33.7 6.9 13.3 6.2 6.0 6.4 7.7 8.3 5.8 6.2 10.5 15.0 11.0 14.9 4.4 7.1 4.8 8.6 2.1 13.2 10.0 10.6 20.5 5.8 10.7 3.6 16.5 7.9 9.2 4.2 5.1 6.5 5.6 6.0 4.0 5.0 4.7 4.4 5.3 3.5 7.9 9.7 8.3 10.1 13.9 12.4 10.1 10.3 15.8 16.7 14.2 13.8 6.1 5.0 17.0 3.6 4.5 6.7 5.4 5.6 18.9 4.2 6.9 15.8 15.6 14.6 11.6 15.4 13.1 12.9 9.0 12.4 15.0 11.7 8.9 9.1 17.7 9.7 13.7 8.7 8.8 10.5 21.1 16.4 24.1 19.2 15.7 10.7 15.5 12.1 13.2 16.7 CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593998-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 11.6;heart muscle: 39.5" "Cell line enriched" "Detected in some" 4 "ASC TERT1: 31.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "pons and medulla: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 2.7" "Low region specificity" "Detected in single" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: " "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" 0.3 0.1 0.3 0.0 0.1 0.0 0.8 0.1 0.1 3.1 0.1 0.1 2.6 0.0 3.4 11.6 0.7 1.2 4.5 39.5 0.0 0.2 2.0 0.0 1.3 0.0 0.2 0.0 0.6 0.1 0.0 1.5 0.6 1.6 1.7 0.0 0.4 0.3 4.6 0.2 5.3 0.4 0.5 0.0 3.5 0.3 3.7 0.0 0.2 0.1 1.7 0.4 0.8 3.2 0.2 0.0 0.5 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 7.3 31.8 0.0 1.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 0.2 0.0 1.6 0.0 CP ENSG00000047457 Ceruloplasmin P00450 3 149162410-149222055 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Copper transport, Ion transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 311.1" "Cell line enriched" "Detected in some" 9 "EFO-21: 80.4" "Cancer enhanced" "Detected in many" "liver cancer: 98.3" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001834, CAB008591" Supported "Secreted to blood" 160000000000 830000000000 "CAB008591: AB_1613734, HPA001834: AB_1078502" "unprognostic (3.58e-1)" "unprognostic (4.24e-1)" "unprognostic (9.61e-2)" "unprognostic (1.80e-2)" "unprognostic (4.14e-2)" "unprognostic (1.02e-2)" "unprognostic (1.06e-1)" "unprognostic (2.97e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "unprognostic (6.03e-2)" "unprognostic (1.70e-1)" "prognostic unfavourable (1.14e-7)" "unprognostic (2.68e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (2.70e-1)" 1.8 0.7 2.6 0.6 5.7 0.4 3.5 2.6 3.5 10.5 2.0 2.5 0.0 1.7 2.3 0.3 1.1 1.5 0.5 6.6 3.6 1.7 1.6 311.1 2.1 2.4 4.2 0.9 0.4 1.2 1.4 5.3 1.9 9.4 2.1 2.7 15.5 6.9 0.4 1.2 2.0 2.6 0.7 4.8 3.5 0.7 0.5 4.4 0.0 2.8 0.4 3.0 3.2 2.9 1.3 0.8 0.6 1.0 0.3 1.3 0.4 0.0 4.7 4.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.7 4.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 1.0 0.5 0.8 0.6 0.8 0.9 0.4 0.5 0.6 1.3 0.4 1.3 0.4 0.3 0.4 0.8 0.4 0.4 2.6 5.7 2.6 3.5 3.6 1.7 4.2 0.9 9.4 4.4 CPA1 CPA ENSG00000091704 "Carboxypeptidase A1" P15085 7 130380339-130388114 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3231 "pancreas: 3541.6" "Cell line enriched" "Detected in some" 5 "AN3-CA: 15.8" "Cancer enriched" "Detected in some" 639 "pancreatic cancer: 1377.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021836, CAB025197, HPA052215" Enhanced "Secreted to digestive system" 17000000 "CAB025197: , HPA021836: AB_1846005, HPA052215: " "unprognostic (8.41e-2)" "unprognostic (9.24e-4)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (3.97e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-6)" "unprognostic (4.99e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (4.37e-2)" 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.0 3541.6 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.0 0.3 0.0 1.9 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266827-130289798 "Enzymes, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 529 "pancreas: 1357.9" "Cell line enhanced" "Detected in some" "AN3-CA: 4.4;CACO-2: 7.3;RH-30: 6.1;SCLC-21H: 3.3" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" 1500000 "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.4 1357.9 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 0.1 2.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 4.4 0.0 0.1 0.0 0.0 0.0 0.7 0.0 7.3 0.0 0.0 1.0 0.0 0.0 1.4 0.0 0.1 1.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.4 0.0 6.1 0.1 0.1 0.6 3.3 0.0 0.2 0.0 2.0 0.0 0.2 0.0 0.0 1.1 0.8 0.6 0.0 0.7 0.2 0.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865256-148897196 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 111.7" "Cell line enriched" "Detected in some" 43 "HEL: 79.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1118 "basophil: 111.7" "Lineage enriched" "Detected in single" 1118 "granulocytes: 111.7" "Low region specificity" "Detected in single" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" 12.4 0.6 0.4 12.0 0.4 5.6 6.2 0.4 0.5 25.4 14.1 0.8 4.4 7.1 14.1 21.2 16.5 3.7 50.9 4.5 0.4 0.2 5.8 2.8 37.3 15.2 0.4 0.4 2.0 7.2 0.7 0.8 1.3 0.5 37.3 16.4 8.5 8.8 5.8 1.4 12.7 20.2 24.3 0.4 1.0 13.7 7.1 0.4 3.6 1.4 9.9 7.1 14.0 8.9 0.0 0.0 111.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 79.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 111.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.4 0.5 0.4 0.2 0.4 0.4 0.5 0.4 CPA4 CPA3 ENSG00000128510 "Carboxypeptidase A4" Q9UI42 7 130293134-130324180 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.0;skin 1: 41.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 30.8;LHCN-M2: 62.5;U-2 OS: 34.2;U-87 MG: 61.4" "Cancer enhanced" "Detected in many" "cervical cancer: 10.0;head and neck cancer: 9.8" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" HPA021030 Approved Nucleoplasm,Centrosome,Cytosol "Secreted in other tissues" 480000 Nucleoplasm "Centrosome, Cytosol" "HPA021030: AB_1846010" "unprognostic (7.60e-3)" "unprognostic (4.00e-2)" "unprognostic (1.59e-3)" "unprognostic (3.63e-3)" "unprognostic (2.24e-2)" "unprognostic (2.91e-2)" "unprognostic (2.78e-2)" "unprognostic (4.36e-3)" "unprognostic (3.23e-1)" "unprognostic (5.79e-2)" "unprognostic (2.37e-3)" "unprognostic (6.49e-2)" "unprognostic (6.21e-10)" "unprognostic (2.39e-1)" "unprognostic (1.67e-1)" "unprognostic (7.56e-2)" "prognostic unfavourable (1.31e-4)" 2.7 2.3 0.1 0.4 0.4 0.2 2.8 0.1 0.4 8.1 1.1 0.3 0.1 0.1 1.1 1.2 18.0 0.2 0.2 4.4 0.1 1.2 1.2 0.2 0.8 0.3 0.1 0.1 1.8 6.9 0.1 1.1 8.8 0.9 0.3 0.1 0.6 4.4 0.1 0.3 41.0 0.5 0.7 0.7 1.7 0.2 2.2 0.1 0.8 0.1 12.3 2.3 1.7 6.7 0.4 0.4 1.6 0.4 1.5 0.4 0.1 20.2 1.1 0.0 0.0 0.1 0.3 0.0 16.2 30.8 16.6 4.1 0.1 1.7 0.0 3.2 6.9 1.2 0.0 8.9 17.2 0.1 0.0 0.0 6.5 0.4 0.4 0.0 0.0 0.2 14.5 1.5 2.1 0.0 0.0 0.0 62.5 0.0 0.0 0.0 0.1 2.4 0.0 16.7 0.0 7.8 0.8 0.0 0.0 10.7 5.1 0.1 0.1 0.0 12.4 4.0 34.2 1.3 1.6 0.0 0.0 0.0 61.4 0.0 0.1 1.0 0.4 0.4 0.4 0.1 0.2 0.3 0.2 0.3 0.0 0.4 0.3 0.3 1.6 1.5 0.2 0.4 0.3 0.1 0.1 0.4 0.1 0.3 0.1 1.2 0.1 0.1 0.9 0.1 CPA5 ENSG00000158525 "Carboxypeptidase A5" Q8WXQ8 7 130344816-130368730 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "blood: 25.2;testis: 30.4" "Cell line enhanced" "Detected in some" "RH-30: 10.9;RT4: 4.9;U-266/84: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 8.0;naive CD8 T-cell: 20.3;T-reg: 25.2" "Lineage enriched" "Detected in single" 114 "T-cells: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020322 Approved Nucleoplasm "Secreted in male reproductive system" Nucleoplasm "HPA020322: AB_10960562" "unprognostic (2.44e-1)" "unprognostic (3.76e-1)" "unprognostic (1.50e-1)" "unprognostic (5.94e-2)" "unprognostic (4.96e-2)" "unprognostic (7.10e-3)" "unprognostic (1.64e-2)" "unprognostic (1.41e-2)" "unprognostic (3.26e-1)" "unprognostic (5.02e-2)" "unprognostic (5.83e-4)" "unprognostic (1.43e-1)" "unprognostic (8.88e-13)" "unprognostic (5.16e-2)" "unprognostic (1.32e-1)" "unprognostic (8.81e-2)" "unprognostic (3.08e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 1.6 0.1 0.1 0.1 0.4 0.0 1.0 0.5 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.8 0.4 0.1 0.1 1.6 0.0 30.4 0.1 0.1 0.1 0.1 0.7 0.8 0.1 0.0 0.0 0.2 0.0 0.0 25.2 3.1 0.8 0.0 0.1 0.6 0.0 0.0 0.0 0.4 3.2 0.2 0.4 2.4 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.0 1.8 0.7 0.7 1.2 0.5 0.0 0.0 0.0 1.1 0.0 1.2 0.0 0.0 1.6 0.1 0.0 0.4 0.0 0.8 0.0 0.0 10.9 0.3 1.4 4.9 1.4 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 8.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 8.0 4.1 0.0 0.0 2.1 20.3 0.0 0.0 0.0 0.0 25.2 3.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 CPB1 ENSG00000153002 "Carboxypeptidase B1" P15086 3 148791102-148860187 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 590 "pancreas: 3628.4" "Cell line enhanced" "Detected in some" "ASC diff: 2.7;EFO-21: 2.9;HDLM-2: 3.0;U-2 OS: 5.1;U-251 MG: 1.5;U-266/84: 2.4" "Group enriched" "Detected in some" 312 "breast cancer: 293.8;pancreatic cancer: 641.4" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "CAB026158, HPA038069, HPA046340" Enhanced "Secreted to digestive system" 6600000 "CAB026158: , HPA038069: , HPA046340: " "unprognostic (6.90e-2)" "unprognostic (3.79e-2)" "unprognostic (3.34e-2)" "unprognostic (2.64e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (6.26e-4)" "unprognostic (1.90e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (7.59e-2)" "unprognostic (4.51e-2)" "unprognostic (5.50e-8)" "unprognostic (3.08e-1)" "unprognostic (1.60e-1)" "unprognostic (4.93e-2)" 0.2 1.7 0.1 0.1 0.2 0.0 0.7 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.2 3628.4 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.7 0.2 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 1.8 1.1 6.1 1.0 3.1 3.5 0.9 0.0 0.0 0.0 0.0 2.7 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 2.9 0.0 0.0 0.0 0.0 0.1 3.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 5.1 0.0 1.5 0.0 2.4 0.6 0.0 0.0 0.0 6.1 0.7 1.1 3.0 0.9 2.2 0.9 1.3 2.6 0.3 1.8 0.9 3.5 4.5 3.1 1.0 1.1 0.6 0.9 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 CPB2 "CPU, PCPB, TAFI" ENSG00000080618 "Carboxypeptidase B2" Q96IY4 13 46053195-46105033 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 82 "liver: 246.8" "Cell line enriched" "Detected in single" 76 "Hep G2: 61.1" "Cancer enriched" "Detected in some" 112 "liver cancer: 268.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA004146 Approved "Secreted to blood" 14000000000 "HPA004146: AB_1078397" "unprognostic (3.44e-2)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (1.89e-2)" "unprognostic (7.69e-2)" "unprognostic (1.17e-2)" "prognostic favourable (2.06e-4)" "unprognostic (1.89e-1)" "unprognostic (2.74e-1)" "unprognostic (2.48e-1)" "unprognostic (3.17e-2)" "unprognostic (4.83e-2)" "unprognostic (3.20e-3)" "unprognostic (1.34e-1)" "unprognostic (7.10e-2)" "unprognostic (3.34e-2)" "unprognostic (9.61e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 246.8 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.5 0.5 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 61.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.4 0.2 0.5 0.4 0.5 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 CPD GP180 ENSG00000108582 "Carboxypeptidase D" O75976 17 30378905-30469989 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HSkMC: 57.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 19.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052796, HPA055465" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear speckles" 930000 "Nucleoplasm, Nuclear speckles" "Nuclear membrane" "HPA052796: , HPA055465: " "unprognostic (1.05e-1)" "unprognostic (1.31e-1)" "unprognostic (3.05e-2)" "unprognostic (3.62e-2)" "unprognostic (6.13e-2)" "unprognostic (1.65e-1)" "unprognostic (7.97e-3)" "unprognostic (4.45e-2)" "unprognostic (2.07e-2)" "unprognostic (2.96e-1)" "unprognostic (1.62e-1)" "unprognostic (3.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.74e-2)" "unprognostic (7.25e-2)" "unprognostic (3.36e-1)" "unprognostic (1.08e-1)" 16.4 8.0 9.8 12.3 12.4 18.1 17.9 9.1 13.3 28.6 16.2 18.5 10.1 12.9 12.6 10.1 10.0 15.2 33.6 10.5 12.8 10.4 13.4 26.8 20.0 14.2 22.1 11.4 7.8 14.7 21.2 14.9 22.3 13.9 11.4 13.3 7.5 59.7 7.9 10.0 7.8 22.0 15.1 25.9 7.9 24.6 25.0 13.5 5.8 37.2 7.7 10.0 11.5 11.6 0.4 3.4 19.3 5.5 2.1 3.8 2.5 12.1 18.5 16.1 16.5 16.8 32.0 5.8 16.8 24.6 11.7 14.4 21.7 7.9 1.5 21.4 19.2 8.7 10.4 21.2 19.7 5.7 14.9 3.4 11.4 13.4 20.4 22.6 9.1 57.0 9.5 14.9 14.5 23.6 6.7 18.0 9.3 2.3 7.2 6.2 4.5 4.2 7.0 18.7 4.7 21.8 13.9 4.0 10.2 20.0 17.3 8.7 16.4 15.7 28.1 11.7 7.7 18.1 16.0 7.2 15.1 5.1 14.9 14.8 9.8 2.8 5.5 6.4 3.4 2.8 3.8 0.2 1.7 2.8 3.4 0.4 1.4 1.7 19.3 2.1 2.3 0.4 1.1 2.5 9.8 12.4 9.1 13.3 12.8 10.4 22.1 11.4 13.9 13.5 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498320 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 203.7" "Cell line enhanced" "Detected in many" "Hep G2: 49.9;SCLC-21H: 70.2;SiHa: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.5" "Lineage enriched" "Detected in single" 16 "T-cells: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" 470000 Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: " "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavourable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavourable (2.12e-4)" 27.7 33.8 123.1 4.4 135.5 0.9 21.5 82.9 203.7 10.7 9.6 31.6 5.3 5.0 13.3 94.3 16.4 15.7 14.0 19.6 116.9 56.3 12.0 6.3 11.0 7.6 56.9 70.7 23.4 35.5 33.9 40.0 2.2 53.0 66.5 8.8 13.2 12.0 20.1 11.0 5.5 6.2 18.5 40.5 2.8 19.2 30.4 53.3 0.9 40.7 4.3 7.7 6.3 9.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.3 9.0 1.7 7.2 0.8 0.4 0.0 3.6 1.3 2.9 0.0 0.0 0.0 2.6 0.0 0.2 3.4 0.7 0.8 0.0 13.2 0.0 3.7 49.9 0.5 0.0 0.0 17.6 3.7 0.0 0.0 0.0 0.0 0.3 1.8 2.5 0.0 0.4 5.7 2.0 0.0 0.0 0.1 0.1 0.5 70.2 23.2 103.0 12.9 0.0 7.7 0.3 0.0 2.8 7.2 0.2 0.2 3.9 0.0 0.3 2.6 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 123.1 135.5 82.9 82.2 116.9 56.3 56.9 70.7 53.0 53.3 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 56.1" "Cell line enhanced" "Detected in many" "ASC diff: 28.8;ASC TERT1: 20.5;HSkMC: 37.0;SiHa: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 15.5;myeloid DC: 11.9" "Group enriched" "Detected in many" 5 "dendritic cells: 11.9;monocytes: 15.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles 5000000 Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favourable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 56.1 6.6 3.8 5.4 7.0 1.1 37.2 1.2 4.9 6.5 12.9 13.2 0.9 1.6 10.7 6.1 4.1 6.4 6.5 2.9 5.3 3.0 22.1 11.6 24.1 13.0 10.9 4.3 7.5 7.8 3.2 1.0 27.9 5.5 6.2 10.8 2.7 3.2 1.7 8.2 13.0 3.7 2.5 6.7 11.4 5.9 5.8 9.3 1.1 5.1 3.5 4.5 4.4 4.4 2.8 11.9 1.3 15.5 0.3 1.3 4.7 0.0 1.5 0.0 0.0 28.8 20.5 0.3 3.8 0.4 0.6 0.9 1.2 1.6 0.2 3.8 0.5 0.0 0.5 1.0 1.6 0.0 1.0 0.0 6.2 0.1 0.1 0.4 0.7 37.0 0.2 0.4 0.8 0.0 0.0 0.0 2.9 0.6 0.0 0.2 0.6 2.0 1.1 0.2 0.0 2.9 2.2 0.1 0.0 27.1 4.2 3.2 0.4 10.1 0.1 0.5 3.1 0.2 0.0 0.1 0.1 4.9 1.7 5.1 2.3 0.3 15.5 0.1 0.1 10.2 0.0 1.4 1.2 0.0 11.9 2.8 0.7 0.1 1.3 0.3 4.7 0.8 1.3 4.7 3.8 7.0 1.2 4.9 5.3 3.0 10.9 4.3 5.5 9.3 CPOX "CPO, CPX, HCP" ENSG00000080819 "Coproporphyrinogen oxidase" P36551 3 98521132-98593723 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 42.9" "Cell line enhanced" "Detected in all" "HEL: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015736, HPA054448" Enhanced Mitochondria 140000 Mitochondria "HPA015736: AB_1847194, HPA054448: " "unprognostic (2.14e-1)" "unprognostic (1.04e-1)" "unprognostic (4.07e-2)" "unprognostic (6.09e-2)" "unprognostic (2.71e-1)" "unprognostic (2.34e-2)" "unprognostic (8.58e-3)" "unprognostic (7.14e-2)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-2)" "unprognostic (1.86e-2)" "prognostic unfavourable (1.04e-5)" "unprognostic (1.62e-1)" "unprognostic (2.67e-2)" "unprognostic (2.15e-2)" "unprognostic (2.57e-1)" 6.6 8.9 12.6 9.0 29.9 30.2 6.6 10.1 21.1 7.5 8.2 29.6 5.7 17.7 8.8 6.4 14.1 6.4 7.2 6.9 17.5 11.7 5.6 29.3 6.3 9.1 42.9 16.2 9.5 6.9 9.9 5.5 14.8 23.7 7.4 10.3 3.4 7.2 7.2 8.5 10.8 12.3 7.7 32.8 9.1 7.7 3.9 36.0 7.7 6.2 7.0 9.8 8.5 10.4 1.7 1.7 0.0 2.1 2.1 3.0 0.7 16.3 7.9 7.0 12.4 13.2 9.8 20.3 10.5 7.6 10.9 12.4 13.1 5.1 1.7 11.9 5.5 11.9 8.7 11.4 18.6 5.2 7.6 56.9 4.5 16.9 6.7 12.0 13.5 7.7 9.6 10.3 4.3 10.3 10.9 7.4 10.2 5.0 12.1 10.3 8.3 14.5 8.6 16.0 7.5 9.2 6.8 4.6 4.6 11.1 3.8 31.6 5.9 7.7 8.6 16.2 15.9 9.2 7.7 11.3 8.9 9.1 16.1 13.2 11.8 0.0 2.1 0.0 1.4 1.0 2.5 1.7 2.4 2.9 1.7 1.5 0.8 3.0 0.0 2.1 0.7 1.1 1.1 0.7 12.6 29.9 10.1 21.1 17.5 11.7 42.9 16.2 23.7 36.0 CPPED1 "CSTP1, FLJ11151" ENSG00000103381 "Calcineurin like phosphoesterase domain containing 1" Q9BRF8 16 12659799-12804017 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 93.6" "Cell line enhanced" "Detected in many" "Hep G2: 44.4;HMC-1: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 93.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040938, HPA041970" Uncertain Supported "Plasma membrane,Cytosol" 380000 Cytosol "Plasma membrane" "HPA040938: AB_10673443, HPA041970: " "prognostic unfavourable (9.72e-4)" "unprognostic (1.70e-1)" "unprognostic (2.04e-3)" "unprognostic (1.05e-2)" "unprognostic (1.13e-3)" "unprognostic (3.86e-2)" "unprognostic (1.35e-1)" "unprognostic (8.67e-2)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (6.26e-2)" "unprognostic (3.64e-1)" "prognostic favourable (1.62e-9)" "unprognostic (5.05e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-3)" "unprognostic (2.40e-2)" 10.9 11.5 8.3 14.3 14.3 9.5 8.5 2.7 11.8 9.2 13.8 20.8 7.4 16.3 8.2 6.2 23.1 7.2 8.9 10.7 11.2 9.5 26.2 31.4 10.4 21.2 20.7 7.7 6.4 4.1 4.3 6.5 36.6 17.6 9.1 11.9 10.2 15.1 7.3 6.4 6.8 20.5 10.0 22.1 27.4 8.1 18.2 13.1 5.8 11.1 8.4 16.9 9.8 9.6 1.5 23.1 93.6 43.7 1.9 1.8 14.6 1.5 9.3 1.0 2.4 3.9 8.4 0.1 17.0 4.6 9.2 7.5 4.5 4.8 2.2 17.7 12.4 0.1 0.0 4.2 9.5 5.2 2.6 19.3 1.4 44.4 2.4 0.0 42.0 8.4 0.9 0.8 6.6 13.7 6.7 1.4 22.4 1.9 1.7 8.9 2.8 1.3 3.6 6.0 4.8 13.8 2.9 4.9 3.2 0.0 15.5 6.1 3.3 4.2 20.4 13.2 2.7 0.0 0.0 0.0 0.3 3.5 2.9 9.8 2.8 6.1 30.6 19.3 1.3 43.7 1.1 1.5 1.1 1.4 23.1 1.0 0.3 0.8 93.6 1.9 40.6 5.6 1.8 14.6 8.3 14.3 2.7 11.8 11.2 9.5 20.7 7.7 17.6 13.1 CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645227-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 94.4" "Cell line enhanced" "Detected in many" "ASC diff: 37.7;ASC TERT1: 43.3;Karpas-707: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 62.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" 51000000 "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favourable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" 17.4 12.6 12.5 10.1 18.3 9.5 15.4 8.3 11.3 26.3 16.5 19.4 21.1 9.4 24.5 19.5 9.1 16.8 20.0 24.1 14.0 9.2 26.4 22.1 13.9 12.3 27.6 8.8 35.3 18.8 20.7 14.2 12.4 16.6 18.1 10.9 19.8 10.9 18.6 5.0 9.1 14.1 30.8 15.3 12.9 14.5 7.3 24.5 1.3 94.4 8.1 7.2 16.9 19.3 1.8 12.8 62.6 17.5 6.3 7.3 8.4 0.6 1.9 1.6 0.4 37.7 43.3 0.5 11.5 17.5 4.1 8.5 1.3 0.8 1.1 9.4 18.2 0.6 0.7 0.8 3.9 10.4 1.5 9.8 1.8 5.7 8.3 2.3 12.7 22.6 2.1 4.7 1.2 1.8 9.5 31.5 9.2 0.6 0.3 4.8 1.2 1.9 2.2 0.3 0.5 8.5 4.4 1.2 0.8 4.1 0.4 8.9 4.4 9.5 8.2 18.0 2.1 0.8 4.2 3.1 0.7 0.4 11.4 7.8 11.9 5.4 17.5 10.8 7.3 12.0 7.3 1.5 5.5 6.3 12.8 1.8 5.0 6.7 62.6 6.3 11.0 3.7 5.7 8.4 12.5 18.3 8.3 11.3 14.0 9.2 27.6 8.8 16.6 24.5 CPS1 ENSG00000021826 "Carbamoyl-phosphate synthase 1" P31327 2 210477682-210679107 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Urea cycle" "Allosteric enzyme, Ligase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 298.3" "Cell line enhanced" "Detected in many" "HeLa: 88.4;SK-BR-3: 26.7" "Cancer enriched" "Detected in many" 8 "liver cancer: 136.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB003781, HPA021400" Enhanced Supported Nucleoli 2100000 Nucleoli "CAB003781: , HPA021400: AB_1847197" "unprognostic (1.67e-2)" "unprognostic (3.72e-2)" "unprognostic (4.02e-2)" "unprognostic (7.21e-7)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "prognostic favourable (6.93e-5)" "unprognostic (1.23e-2)" "unprognostic (2.65e-1)" "unprognostic (1.35e-2)" "unprognostic (5.38e-2)" "unprognostic (1.94e-3)" "unprognostic (2.38e-4)" "unprognostic (5.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.14e-2)" "unprognostic (3.74e-2)" 0.4 0.1 0.5 0.3 1.6 0.0 0.8 0.3 0.7 0.4 0.2 0.7 0.3 31.5 0.3 0.7 0.5 0.2 0.4 0.3 0.5 0.4 0.6 298.3 0.2 0.3 1.5 0.8 0.7 0.2 0.0 0.4 1.1 1.4 0.3 0.0 0.6 0.2 0.2 0.3 0.3 17.2 0.4 2.3 0.3 0.2 1.3 0.5 0.0 0.4 0.4 0.1 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.3 2.3 6.2 4.2 4.1 7.2 6.6 2.2 2.7 2.6 4.1 0.6 0.0 1.0 0.1 2.4 1.1 0.2 3.7 6.6 0.0 1.9 3.9 88.4 5.5 1.3 2.0 0.0 3.7 2.8 5.2 5.3 0.2 3.9 0.3 4.3 1.1 0.1 0.2 2.4 0.6 0.2 5.7 0.5 5.6 0.0 0.1 0.4 15.5 26.7 3.0 0.0 0.6 2.9 6.8 2.1 2.0 4.8 0.0 0.3 0.0 4.5 4.3 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.3 0.7 0.5 0.4 1.5 0.8 1.4 0.5 CPT1A "CPT1, CPT1-L, L-CPT1" ENSG00000110090 "Carnitine palmitoyltransferase 1A" P50416 11 68754620-68844410 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008835 Supported Supported Mitochondria 790000 Mitochondria "HPA008835: AB_1078563" "prognostic unfavourable (3.84e-4)" "unprognostic (1.38e-3)" "unprognostic (3.04e-3)" "unprognostic (2.46e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (2.17e-1)" "unprognostic (4.99e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-1)" "prognostic favourable (2.67e-7)" "unprognostic (9.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-3)" 18.0 18.3 9.9 9.9 12.1 15.8 24.4 7.0 10.3 12.8 31.9 8.2 14.1 33.7 17.0 7.2 11.2 12.8 14.7 14.6 12.0 6.6 30.6 62.0 13.1 10.1 10.5 8.6 17.0 24.4 16.9 13.8 8.7 10.8 15.6 22.0 19.7 12.9 11.4 6.9 10.3 33.4 16.9 8.7 18.9 16.8 10.4 9.0 17.9 13.2 7.5 7.6 11.3 30.2 2.5 11.9 10.6 8.6 5.7 8.8 2.5 8.3 14.8 2.1 14.5 9.5 8.6 0.6 6.7 5.5 5.3 1.1 0.5 28.3 0.0 24.8 17.6 27.5 18.8 4.0 1.6 13.4 1.8 20.5 16.2 6.8 14.2 11.9 24.9 8.9 1.9 10.6 6.4 18.8 2.1 16.9 4.8 24.0 9.7 21.1 0.2 15.8 27.1 0.3 36.5 12.5 20.9 0.3 9.5 18.5 35.7 5.9 31.9 11.6 18.8 11.6 0.2 23.2 9.6 13.2 16.8 8.5 12.2 8.8 12.6 9.2 7.8 10.6 8.8 8.6 5.1 2.3 5.5 5.3 5.0 2.5 3.4 7.0 3.8 5.7 7.2 11.9 2.9 2.5 9.9 12.1 7.0 10.3 12.0 6.6 10.5 8.6 10.8 9.0 CPT1B "CPT1-M, M-CPT1" ENSG00000205560 "Carnitine palmitoyltransferase 1B" Q92523 22 50568861-50578465 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 162.2;skeletal muscle: 59.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA029583 Approved "HPA029583: AB_10600864" "unprognostic (1.66e-1)" "unprognostic (2.99e-1)" "unprognostic (6.71e-3)" "unprognostic (2.53e-2)" "unprognostic (1.36e-1)" "unprognostic (1.18e-3)" "unprognostic (8.89e-2)" "unprognostic (7.16e-2)" "unprognostic (5.01e-2)" "unprognostic (9.50e-2)" "unprognostic (1.10e-3)" "unprognostic (9.76e-3)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" "unprognostic (1.14e-1)" "unprognostic (8.43e-2)" "unprognostic (3.15e-5)" 4.3 1.5 1.7 2.9 2.7 3.3 2.8 9.1 2.0 1.7 3.1 1.8 1.6 3.8 1.6 2.9 3.7 0.9 1.6 162.2 2.1 1.9 4.0 4.2 1.9 3.5 2.5 1.6 1.6 3.1 17.2 4.5 2.3 2.2 2.5 2.9 5.2 4.3 1.6 59.8 3.8 3.7 1.6 2.2 5.0 3.8 19.7 2.3 1.9 5.2 39.6 4.5 2.0 1.6 0.5 2.3 0.7 0.4 2.3 1.6 0.3 5.2 4.8 15.5 5.7 3.5 2.1 12.2 0.6 2.0 2.6 3.0 2.3 4.6 10.4 1.7 1.2 8.7 8.2 1.8 2.3 4.2 9.1 5.2 14.1 2.4 0.9 5.4 15.2 1.2 14.1 1.9 3.1 0.4 1.8 17.6 2.5 7.4 2.1 10.6 3.4 3.2 9.6 5.1 2.3 6.6 12.4 4.3 8.4 3.9 6.3 6.5 6.9 11.4 1.1 7.6 8.1 5.0 1.8 15.0 3.4 5.4 3.5 9.7 5.1 0.0 0.4 0.5 1.0 0.1 0.0 0.5 1.6 0.3 2.3 0.2 0.4 0.2 0.7 2.3 0.2 0.3 0.1 0.3 1.7 2.7 9.1 2.0 2.1 1.9 2.5 1.6 2.2 2.3 CPT1C "CPT1P, CPTIC, FLJ23809" ENSG00000169169 "Carnitine palmitoyltransferase 1C" Q8TCG5 19 49690898-49713731 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.0" "Cell line enhanced" "Detected in many" "AF22: 18.4;AN3-CA: 15.5;SH-SY5Y: 33.2;U-87 MG: 13.9" "Cancer enhanced" "Detected in many" "glioma: 9.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014529, HPA063621" Approved Approved Centrosome Centrosome "HPA014529: AB_1847206, HPA063621: " "unprognostic (1.09e-1)" "unprognostic (6.25e-2)" "unprognostic (1.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.73e-1)" "unprognostic (1.46e-3)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "unprognostic (1.06e-1)" "unprognostic (2.49e-1)" "prognostic favourable (1.84e-4)" "unprognostic (4.36e-1)" "unprognostic (1.92e-10)" "unprognostic (9.44e-4)" "unprognostic (3.35e-2)" "unprognostic (3.91e-1)" "unprognostic (4.72e-3)" 3.4 9.3 11.2 3.1 18.9 0.8 1.1 16.3 34.0 4.1 1.9 8.9 0.2 2.7 6.4 5.3 1.8 4.1 7.6 2.8 11.9 12.8 1.6 1.6 2.5 2.6 8.0 13.4 3.8 1.2 0.7 15.6 1.9 11.4 2.8 1.7 7.4 1.5 4.8 1.7 1.5 2.4 7.8 6.6 4.2 1.4 4.1 6.3 0.0 1.7 0.2 1.7 4.4 1.9 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 18.4 15.5 6.7 5.2 0.0 5.8 11.7 7.5 10.6 0.3 0.0 0.3 0.0 5.8 1.3 0.0 0.0 4.0 0.2 0.0 0.0 0.0 0.0 10.8 0.0 0.0 6.1 0.0 6.1 0.0 10.4 0.0 0.0 0.4 0.3 0.1 0.0 0.8 3.8 0.0 0.0 0.0 0.4 0.0 12.9 33.2 0.0 0.0 0.0 0.0 0.0 8.4 0.3 0.1 3.5 2.9 0.1 1.3 0.1 13.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 11.2 18.9 16.3 23.4 11.9 12.8 8.0 13.4 11.4 6.3 CPT2 "CPT1, CPTASE" ENSG00000157184 "Carnitine palmitoyltransferase 2" P23786 1 53196429-53214197 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028201, HPA028202, HPA028214" Enhanced Supported Nucleoplasm,Nucleoli,Mitochondria "Nucleoplasm, Nucleoli, Mitochondria" "HPA028201: AB_10599177, HPA028202: AB_10599942, HPA028214: AB_10601958" "unprognostic (2.43e-1)" "unprognostic (2.27e-1)" "prognostic favourable (5.27e-4)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (9.34e-2)" "unprognostic (6.48e-2)" "unprognostic (1.75e-2)" "unprognostic (2.86e-1)" "unprognostic (1.67e-1)" "unprognostic (3.00e-2)" "unprognostic (8.97e-2)" "prognostic favourable (1.46e-12)" "unprognostic (4.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.79e-2)" "unprognostic (2.95e-2)" 7.5 15.5 5.3 6.8 6.1 2.3 6.5 4.0 7.2 5.1 15.4 9.4 10.7 16.6 5.1 7.6 10.5 5.4 11.3 21.4 4.3 4.5 19.8 69.0 6.9 8.3 5.7 3.7 5.3 15.9 10.7 11.5 18.1 6.4 6.0 15.6 13.8 11.8 12.2 13.6 6.0 18.9 5.5 5.2 10.3 10.1 11.2 4.7 9.7 8.3 7.2 10.3 8.0 4.9 5.9 12.4 10.0 13.1 4.8 8.0 6.5 7.8 3.3 7.7 7.5 6.6 3.9 8.8 4.9 5.0 7.1 6.6 1.6 6.7 13.5 7.5 2.3 7.9 14.3 11.3 6.0 7.4 8.4 7.7 4.5 1.3 9.8 7.3 7.4 8.4 9.7 5.1 4.4 4.8 9.8 4.8 4.4 4.6 5.7 6.0 14.4 8.8 6.6 7.3 14.3 8.8 7.4 11.5 7.7 9.8 12.5 18.5 14.5 15.6 4.7 4.0 3.2 7.0 4.0 14.9 9.1 8.3 5.1 8.4 5.8 4.1 8.4 10.0 5.1 12.6 6.2 4.5 4.9 5.9 12.4 5.9 8.0 5.5 5.1 4.8 13.1 6.4 7.0 6.5 5.3 6.1 4.0 7.2 4.3 4.5 5.7 3.7 6.4 4.7 CPVL ENSG00000106066 "Carboxypeptidase, vitellogenic like" Q9H3G5 7 28995231-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 111.9;lymphoid tissue: 84.0" "Cell line enriched" "Detected in many" 4 "RPTEC TERT1: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 95.8;intermediate monocyte: 81.6;myeloid DC: 111.9" "Group enriched" "Detected in many" 52 "dendritic cells: 111.9;monocytes: 95.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" 510000 "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: , HPA056466: " "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavourable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavourable (4.99e-4)" 19.0 6.2 4.0 15.0 9.1 11.9 7.7 11.6 3.4 9.1 10.0 7.7 4.2 7.6 6.9 20.4 6.4 7.2 10.2 30.2 6.1 4.4 39.1 12.3 13.5 30.5 6.6 2.3 10.1 8.5 0.2 6.1 31.3 20.1 8.4 6.0 15.8 3.5 5.2 7.9 5.1 13.3 8.1 9.7 84.0 4.7 10.6 4.2 29.7 51.9 5.0 8.1 11.0 15.7 0.1 111.9 1.9 95.8 0.5 0.3 74.4 0.2 0.0 3.2 0.0 0.0 0.0 30.9 0.0 0.0 0.3 0.0 9.3 0.0 0.0 14.7 0.1 0.5 8.2 0.6 0.1 0.0 7.6 10.4 0.1 22.3 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.1 6.9 0.0 0.2 0.0 9.6 0.0 5.0 2.5 0.0 0.0 0.0 129.2 3.5 1.9 1.5 8.5 20.2 15.6 2.4 7.7 0.0 0.0 0.1 0.0 1.8 2.8 31.1 0.1 0.0 3.9 3.3 1.0 95.8 0.4 0.2 81.6 0.3 0.1 0.1 0.1 111.9 0.1 0.1 0.1 1.9 0.5 26.0 2.9 0.1 74.4 4.0 9.1 11.6 3.4 6.1 4.4 6.6 2.3 20.1 4.2 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 19 "BJ: 9.9;fHDF/TERT166: 38.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "pons and medulla: 16.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" "HPA048375: " "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favourable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 17.0 4.1 0.8 5.0 2.1 0.1 12.3 1.3 1.6 6.4 40.9 6.7 5.7 3.8 12.2 37.8 20.0 9.1 9.4 14.3 1.7 4.0 6.6 1.5 4.6 3.7 6.1 0.7 12.8 3.2 1.9 7.1 11.6 16.9 14.7 4.5 26.5 5.6 8.3 5.0 4.5 9.1 45.5 21.6 13.8 14.4 7.7 3.4 2.6 9.5 11.9 4.0 32.5 20.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.4 0.6 0.0 0.0 0.0 0.0 0.0 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 2.1 1.3 1.6 1.7 4.0 6.1 0.7 16.9 3.4 CPZ ENSG00000109625 "Carboxypeptidase Z" Q66K79 4 8592660-8619759 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 63.2" "Cell line enhanced" "Detected in some" "BEWO: 29.2;BJ: 16.8;BJ hTERT+: 22.6;RH-30: 24.8;U-2197: 18.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA078608 Approved "Plasma membrane" "Secreted to extracellular matrix" "Plasma membrane" "HPA078608: " "unprognostic (2.58e-1)" "unprognostic (7.16e-2)" "unprognostic (4.83e-2)" "unprognostic (1.42e-1)" "unprognostic (7.77e-2)" "unprognostic (2.20e-2)" "unprognostic (2.98e-1)" "unprognostic (7.77e-2)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (7.23e-8)" "unprognostic (4.30e-3)" "unprognostic (3.58e-2)" "unprognostic (6.13e-4)" "unprognostic (5.51e-2)" 4.3 0.9 0.3 2.8 1.1 0.0 5.4 1.1 1.6 15.7 1.8 1.5 27.1 0.1 7.9 24.1 3.0 7.4 12.9 2.4 0.4 0.3 1.5 0.8 2.9 0.7 1.5 0.4 63.2 1.1 0.3 2.3 18.9 2.3 4.1 0.5 4.4 0.8 20.6 0.3 5.5 1.2 10.3 1.3 0.7 1.7 4.4 0.1 1.6 3.5 0.1 2.2 9.8 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.1 0.0 0.7 2.2 0.2 29.2 16.8 22.6 6.3 2.5 0.7 0.3 0.0 1.6 9.2 0.0 0.0 0.0 2.4 0.0 1.2 0.0 0.1 0.3 2.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.5 0.0 0.0 3.9 9.2 0.0 24.8 0.0 0.0 0.5 0.0 0.0 0.6 0.2 0.0 0.1 0.0 0.0 0.9 1.2 18.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 1.1 1.6 0.4 0.3 1.5 0.4 2.3 0.1 CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094810-129111189 "Enzymes, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 98.6;testis: 71.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Nucleoplasm,Nuclear membrane" 13000 "Nucleoplasm, Nuclear membrane" "HPA019230: AB_1847212, HPA020260: AB_1847210, HPA022815: AB_1847209" "unprognostic (5.13e-2)" "unprognostic (9.79e-3)" "unprognostic (1.99e-2)" "prognostic favourable (2.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-2)" "unprognostic (3.13e-3)" "unprognostic (2.03e-1)" "prognostic favourable (0.00e+0)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (1.26e-2)" "unprognostic (7.65e-2)" 11.6 13.4 8.4 4.6 9.2 5.9 10.7 7.5 15.9 8.3 15.4 8.6 6.2 24.3 6.5 9.5 9.4 5.4 10.0 17.3 7.7 7.9 12.9 50.0 4.2 3.1 8.3 9.1 7.3 33.1 16.8 3.2 7.9 9.3 10.5 4.4 8.1 14.7 7.9 98.6 7.0 22.8 8.3 5.2 4.6 8.1 71.7 4.4 2.4 8.0 20.2 4.4 9.3 6.8 2.6 11.3 6.0 11.3 6.0 10.0 8.1 0.1 18.3 6.4 13.2 12.0 16.1 9.4 7.8 8.7 9.5 6.0 3.8 7.4 0.7 4.7 13.1 3.3 1.7 2.8 3.4 11.8 0.4 3.6 9.2 14.8 17.1 0.1 14.0 14.7 0.0 8.0 0.2 12.4 1.7 3.8 9.8 3.7 0.3 8.1 1.5 8.2 9.1 12.3 6.1 9.2 0.3 2.1 6.6 0.0 4.2 2.7 26.7 4.0 11.2 14.3 1.0 17.9 7.7 13.0 11.0 0.0 16.9 2.2 9.1 2.5 11.3 6.0 5.0 7.4 10.0 2.4 6.9 6.6 11.3 2.6 4.3 4.7 2.9 6.0 7.3 5.3 6.4 8.1 8.4 9.2 7.5 15.9 7.7 7.9 8.3 9.1 9.3 4.4 CREBBP "CBP, KAT3A, RSTS, RTS" ENSG00000005339 "CREB binding protein" Q92793 16 3725054-3880726 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004212, HPA055861" Supported Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "CAB004212: AB_626817, HPA055861: " "unprognostic (1.17e-1)" "unprognostic (8.51e-2)" "unprognostic (1.60e-1)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (5.09e-2)" "unprognostic (9.59e-3)" "unprognostic (6.98e-2)" "unprognostic (8.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "prognostic favourable (6.24e-5)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (3.97e-2)" "unprognostic (8.23e-2)" 18.5 10.9 17.2 22.8 17.5 37.0 17.4 42.6 18.8 20.1 17.2 16.8 17.1 9.9 25.1 15.2 14.1 18.9 21.3 14.5 17.1 8.7 11.1 12.3 16.9 14.4 20.5 12.0 31.6 23.4 24.3 13.0 13.3 15.8 18.4 11.6 14.6 14.9 16.7 28.2 20.4 16.4 17.0 13.6 17.4 14.7 29.1 20.2 29.6 19.5 13.8 16.1 19.0 29.9 4.7 2.3 10.6 3.8 2.0 2.7 1.1 5.5 14.3 18.6 8.2 11.4 11.3 9.6 8.0 13.5 13.9 13.5 12.9 10.5 15.4 9.6 15.3 10.8 21.4 6.6 15.8 26.0 8.6 12.1 13.2 8.2 12.6 12.1 17.4 10.0 6.7 15.4 18.6 10.4 13.7 21.1 7.5 19.1 8.0 5.8 15.2 5.9 37.8 14.7 11.8 5.4 7.5 15.5 10.2 13.7 13.5 8.1 12.0 11.9 16.1 17.0 16.9 8.7 7.3 9.9 10.6 29.9 3.4 7.3 11.9 2.9 1.7 1.3 2.7 2.2 1.4 4.7 1.3 2.0 1.0 3.3 1.4 1.7 10.6 2.0 3.8 2.3 1.3 1.1 17.2 17.5 42.6 18.8 17.1 8.7 20.5 12.0 15.8 20.2 CROT COT ENSG00000005469 "Carnitine O-octanoyltransferase" Q9UKG9 7 87345681-87399795 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 34.6;RT4: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019052, HPA019364, HPA019365" Enhanced Approved Vesicles Vesicles "HPA019052: AB_1847172, HPA019364: AB_1847173, HPA019365: AB_1847174" "unprognostic (2.80e-2)" "unprognostic (6.47e-2)" "unprognostic (1.75e-1)" "unprognostic (4.56e-2)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" "unprognostic (9.93e-3)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (9.84e-2)" "unprognostic (3.48e-1)" "prognostic favourable (2.55e-6)" "unprognostic (3.52e-2)" "unprognostic (1.34e-1)" "unprognostic (7.60e-3)" "prognostic favourable (4.02e-4)" 4.6 10.1 9.3 5.1 9.6 1.6 10.5 7.4 8.4 9.0 9.4 5.5 24.1 19.6 10.0 12.6 17.0 6.8 8.7 5.9 5.2 5.4 12.3 21.5 4.2 3.4 5.4 6.6 7.2 4.6 15.5 9.1 13.7 5.8 14.8 7.0 9.8 8.3 32.3 7.2 15.0 19.1 8.8 6.8 4.8 4.9 3.8 4.7 7.4 27.1 8.4 8.0 22.4 15.3 2.2 2.3 3.4 5.5 13.0 9.5 3.0 7.0 5.2 6.5 2.2 6.2 5.7 4.8 7.5 7.1 4.6 5.0 2.8 3.7 3.0 6.7 6.3 8.9 1.0 10.0 6.5 4.2 4.5 6.5 3.7 3.5 4.0 4.0 4.0 4.6 34.6 3.7 2.9 6.5 0.3 4.3 12.0 6.9 5.0 4.0 1.4 7.9 2.3 8.9 0.5 5.9 33.8 1.0 5.1 9.2 10.6 4.8 6.7 1.4 3.4 10.7 4.6 14.4 7.1 6.6 9.4 4.1 7.2 0.0 6.3 2.0 1.4 3.4 7.4 1.7 9.5 2.2 7.5 6.0 2.0 2.2 6.1 6.6 0.9 13.0 5.5 2.3 6.3 3.0 9.3 9.6 7.4 8.4 5.2 5.4 5.4 6.6 5.8 4.7 CRYL1 "GDH, lambda-CRY, MGC149525, MGC149526" ENSG00000165475 "Crystallin lambda 1" Q9Y2S2 13 20403666-20525873 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 104.0;liver: 80.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040403 Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" 210000 "Nucleoplasm, Nucleoli" "Golgi apparatus, Plasma membrane" "HPA040403: AB_10795632" "unprognostic (1.84e-1)" "unprognostic (1.25e-1)" "unprognostic (3.25e-2)" "prognostic favourable (1.76e-5)" "unprognostic (3.10e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-3)" "unprognostic (4.75e-3)" "unprognostic (1.19e-1)" "unprognostic (4.09e-2)" "unprognostic (2.12e-2)" "unprognostic (8.80e-2)" "prognostic favourable (2.30e-9)" "unprognostic (9.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (3.11e-1)" 9.8 8.9 21.5 8.8 22.9 3.5 7.0 10.4 17.4 11.8 35.1 26.7 18.9 61.0 9.2 18.0 7.4 9.3 16.1 9.3 18.8 19.8 104.0 80.8 6.8 5.9 24.5 12.3 7.3 15.4 5.3 10.4 5.6 16.8 11.2 16.5 17.2 13.1 20.1 5.4 4.1 45.7 8.0 32.0 6.5 12.0 2.7 16.4 3.2 11.9 5.6 5.5 8.6 5.9 9.3 25.7 1.8 24.3 6.0 15.6 17.5 3.4 3.0 2.6 19.0 14.5 16.8 2.6 4.9 8.8 2.1 1.7 1.1 3.2 0.0 9.3 6.7 0.8 2.5 4.4 2.2 8.3 2.1 6.1 0.3 23.7 8.3 1.9 5.5 9.9 2.8 1.6 10.0 23.0 0.4 2.4 5.6 12.5 5.2 3.1 0.1 4.6 2.7 1.7 0.4 18.3 7.4 1.8 2.2 2.9 1.4 21.8 9.4 7.8 22.0 2.7 1.2 6.5 3.0 3.4 0.7 0.0 5.1 3.4 10.9 1.8 21.8 1.4 10.5 24.3 8.5 9.3 14.0 10.0 25.7 9.1 11.0 10.2 0.7 6.0 20.1 2.8 15.6 17.5 21.5 22.9 10.4 17.4 18.8 19.8 24.5 12.3 16.8 16.4 CRYM DFNA40 ENSG00000103316 "Crystallin mu" Q14894 16 21238874-21303083 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 23.7;brain: 61.3;heart muscle: 45.9" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 30.5" "Cancer enhanced" "Detected in many" "prostate cancer: 14.6" "Region enhanced" "Detected in many" "basal ganglia: 61.3" "Cell type enriched" "Detected in single" 26 "plasmacytoid DC: 23.7" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.7" "Group enriched" "Detected in many" 12 "amygdala: 129.0;basal ganglia: 245.8;cerebral cortex: 127.4;hippocampal formation: 355.0" "Low region specificity" "Detected in all" "HPA019086, HPA030619" Enhanced Supported Cytosol 110000 Cytosol "HPA019086: AB_1847260, HPA030619: AB_2673551" "unprognostic (1.32e-1)" "unprognostic (2.93e-3)" "unprognostic (8.96e-2)" "unprognostic (1.44e-1)" "unprognostic (2.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.88e-1)" "unprognostic (5.75e-3)" "unprognostic (2.81e-1)" "unprognostic (7.37e-2)" "unprognostic (2.05e-2)" "unprognostic (5.95e-2)" "unprognostic (2.11e-3)" "unprognostic (7.79e-3)" "unprognostic (2.49e-2)" "unprognostic (1.87e-3)" "unprognostic (1.31e-1)" 1.4 0.5 7.6 0.5 61.3 0.5 1.0 15.6 21.2 1.8 2.2 0.0 0.0 0.7 0.8 0.3 2.3 0.5 2.3 45.9 6.5 2.1 17.8 4.2 2.7 0.5 1.0 15.5 0.5 0.8 0.6 3.3 0.3 0.1 10.5 2.6 1.0 4.8 0.3 4.0 1.4 1.0 2.0 0.9 0.5 0.6 1.6 1.2 0.0 0.5 0.0 1.5 8.3 0.8 0.9 23.7 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 1.6 0.0 0.0 0.0 0.4 7.0 0.0 0.7 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.0 0.1 0.2 0.1 0.0 0.3 3.2 0.0 0.0 0.0 0.2 30.5 0.0 1.2 1.7 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.2 2.6 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 23.7 0.0 0.3 7.6 61.3 15.6 20.7 6.5 2.1 1.0 15.5 0.1 1.2 CRYZ ENSG00000116791 "Crystallin zeta" Q08257 1 74705482-74733408 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 100.0;liver: 79.8" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021921, HPA023290" Approved Supported Cytosol 7200000 Cytosol "HPA021921: AB_1847262, HPA023290: AB_1847263" "unprognostic (3.64e-2)" "unprognostic (3.38e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.32e-3)" "unprognostic (5.79e-2)" "unprognostic (6.29e-2)" "unprognostic (1.04e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-1)" "unprognostic (6.38e-3)" "unprognostic (2.19e-1)" "unprognostic (1.35e-3)" "unprognostic (3.12e-1)" "unprognostic (7.50e-2)" "unprognostic (2.94e-1)" "unprognostic (7.32e-2)" 6.0 13.4 7.5 4.6 5.4 0.2 8.8 4.2 5.9 19.8 12.6 3.9 27.1 11.3 11.9 29.1 9.7 11.5 15.7 10.4 6.0 9.0 100.0 79.8 7.1 4.8 6.5 3.5 9.4 26.1 13.2 17.2 3.7 11.1 13.8 4.9 9.4 5.9 21.9 5.6 5.6 19.8 14.1 6.8 5.4 9.5 4.9 5.9 7.1 17.1 7.9 5.8 14.8 15.8 18.2 8.9 4.7 8.6 14.4 21.7 9.0 2.5 24.3 12.6 3.6 14.5 15.9 8.5 7.8 12.4 11.4 12.8 19.0 10.0 13.6 13.8 15.2 6.7 10.2 9.9 18.6 15.7 4.1 5.6 7.6 38.0 7.6 4.8 11.7 7.3 8.8 18.2 3.3 9.5 17.8 4.9 23.7 5.6 8.7 8.1 9.4 15.8 5.6 11.8 5.0 96.4 7.8 3.5 6.2 1.8 13.2 8.6 11.8 1.6 4.6 2.7 6.8 8.6 11.8 3.5 6.8 6.7 22.3 1.9 7.8 4.7 5.2 0.9 18.2 7.7 14.7 18.2 17.9 16.7 8.9 13.7 15.7 16.7 0.8 14.4 8.6 7.5 21.7 9.0 7.5 5.4 4.2 5.9 6.0 9.0 6.5 3.5 11.1 5.9 CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300392 "Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 125.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria 4400000 Mitochondria "CAB075750: , CAB075751: , CAB075752: , CAB075753: , CAB075754: , HPA038460: AB_2676023, HPA038461: AB_2676024" "unprognostic (7.67e-3)" "unprognostic (3.80e-1)" "unprognostic (2.59e-2)" "unprognostic (2.50e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (3.34e-2)" "unprognostic (2.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.97e-2)" "prognostic favourable (1.17e-4)" "unprognostic (1.20e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" 37.1 35.5 11.9 16.3 20.4 19.3 55.6 28.5 43.8 17.2 27.4 14.1 11.3 25.3 19.9 10.8 31.7 16.5 14.0 79.2 11.2 14.5 26.7 12.3 17.3 30.8 12.3 14.2 16.9 20.7 28.1 14.3 11.9 24.8 16.2 32.7 19.8 23.1 17.5 125.9 22.8 27.0 21.2 15.0 18.4 21.4 7.9 11.1 20.7 17.9 48.2 26.1 22.9 19.1 19.5 37.1 59.6 27.8 15.9 19.7 18.2 35.4 38.4 31.3 40.7 41.7 38.8 20.4 29.6 29.1 52.1 36.5 54.1 34.9 69.4 29.1 37.3 38.5 86.6 44.5 49.9 24.1 44.0 47.7 27.9 39.0 23.4 58.3 34.3 42.7 42.6 40.9 49.6 58.6 49.3 41.7 45.5 28.5 48.2 18.0 24.9 55.5 47.0 36.8 52.4 32.3 36.1 41.2 27.0 38.3 45.6 30.0 63.5 34.0 38.8 26.3 36.9 37.1 31.2 27.5 41.9 45.2 24.3 42.9 24.7 14.5 22.0 59.6 15.2 27.8 19.7 19.5 18.3 14.3 37.1 16.7 19.4 15.4 9.8 15.9 27.0 20.5 19.3 18.2 11.9 20.4 28.5 43.8 11.2 14.5 12.3 14.2 24.8 11.1 CSAD "CSD, PCAP" ENSG00000139631 "Cysteine sulfinic acid decarboxylase" Q9Y600 12 53157663-53180909 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 38.7;T-47d: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 16.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039487 Approved "Intracellular and membrane" "HPA039487: AB_10672776" "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "prognostic unfavourable (9.50e-4)" "unprognostic (1.57e-1)" "unprognostic (7.99e-2)" "prognostic favourable (6.33e-4)" "prognostic favourable (1.37e-4)" "unprognostic (2.46e-2)" "unprognostic (7.87e-3)" "unprognostic (1.01e-1)" "prognostic favourable (3.39e-4)" "unprognostic (3.48e-2)" "prognostic unfavourable (1.93e-6)" "unprognostic (4.59e-2)" "unprognostic (3.47e-1)" "unprognostic (1.38e-1)" "prognostic favourable (6.81e-6)" 30.3 11.4 23.4 12.4 17.8 24.8 26.0 26.4 20.8 17.8 13.1 23.5 24.7 12.4 27.7 39.4 12.3 16.5 14.6 9.9 19.3 10.2 14.9 39.5 12.7 12.5 18.3 22.4 24.6 15.3 16.4 18.4 9.5 17.6 24.8 12.1 19.5 23.2 19.6 12.9 41.9 12.0 14.8 18.9 16.5 12.4 18.5 18.9 12.1 16.0 9.9 10.2 10.5 16.2 2.1 2.2 16.3 2.0 1.5 3.0 0.4 1.6 2.9 7.1 3.0 38.7 16.0 2.6 6.3 1.4 2.7 2.2 1.8 3.9 2.1 4.8 3.4 5.6 3.1 4.9 1.6 2.8 3.8 3.4 7.2 3.7 3.5 1.3 2.2 19.6 6.2 4.0 5.1 2.4 3.5 19.1 2.5 13.4 0.7 4.0 1.4 2.8 2.8 0.4 4.9 3.5 4.2 3.6 2.8 6.2 9.0 2.3 23.5 2.8 5.5 7.9 1.6 2.3 1.8 5.5 1.3 1.1 6.6 3.6 3.1 3.5 2.0 2.2 1.3 1.1 0.8 1.2 1.9 0.8 0.9 2.1 2.5 1.4 16.3 1.5 1.2 2.2 3.0 0.4 23.4 17.8 26.4 20.8 19.3 10.2 18.3 22.4 17.6 18.9 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 82.5;lymphoid tissue: 82.6" "Group enriched" "Detected in some" 5 "BEWO: 50.6;SK-BR-3: 19.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 60.7;non-classical monocyte: 82.5" "Lineage enriched" "Detected in many" 4 "monocytes: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" 1500000000 "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavourable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavourable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 20.9 12.4 18.2 28.1 18.9 1.8 7.7 2.8 13.5 9.3 8.3 25.4 1.1 9.2 5.9 13.1 8.4 7.9 16.1 8.7 16.4 13.7 7.8 15.1 13.7 25.4 21.3 6.0 5.3 5.2 5.9 6.4 52.1 17.1 8.5 8.4 16.8 8.0 8.7 3.0 5.8 14.5 16.2 25.8 82.6 9.0 4.9 23.0 3.1 4.2 2.9 8.2 16.4 4.7 0.0 19.1 2.9 82.5 0.0 0.1 13.9 1.7 0.0 0.0 0.0 0.8 0.2 50.6 0.1 0.0 0.0 0.0 1.5 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.1 0.0 19.3 0.0 0.0 7.2 0.0 0.3 0.0 0.0 1.3 0.0 0.1 0.0 2.6 0.9 0.0 0.4 18.1 0.5 0.1 60.7 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 2.9 0.0 82.5 1.4 0.0 13.9 18.2 18.9 2.8 13.4 16.4 13.7 21.3 6.0 17.1 23.0 CSGALNACT1 "ChGn, CSGalNAcT-1, FLJ11264" ENSG00000147408 "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" Q8TDX6 8 19404161-19758029 "Enzymes, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 57.7" "Cell line enhanced" "Detected in some" "A549: 28.6;BJ hTERT+: 16.1;RPTEC TERT1: 20.0;U-2197: 18.3;U-87 MG: 13.2" "Cancer enhanced" "Detected in all" "prostate cancer: 22.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 20.1;granulocytes: 10.3;T-cells: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061336 Uncertain "Actin filaments" "Intracellular and membrane" "Actin filaments" "HPA061336: " "unprognostic (8.90e-2)" "unprognostic (1.57e-2)" "unprognostic (4.66e-2)" "unprognostic (2.58e-1)" "unprognostic (6.03e-2)" "unprognostic (3.17e-3)" "unprognostic (9.78e-2)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (1.46e-3)" "unprognostic (1.02e-2)" 13.8 8.7 22.7 6.0 15.4 6.8 7.2 3.8 21.4 13.0 3.8 9.2 4.0 2.8 7.1 5.9 21.2 8.7 10.8 23.8 17.7 8.2 5.3 2.3 7.9 10.5 9.1 18.7 38.6 10.9 4.2 5.9 25.1 7.0 21.7 2.1 2.6 5.8 7.3 3.9 4.2 4.2 17.2 8.6 6.3 5.4 2.7 10.3 4.0 57.7 4.5 6.1 18.9 9.7 20.1 1.7 10.3 1.2 3.2 25.5 4.8 0.7 28.6 0.2 0.0 4.8 1.1 3.7 0.6 16.1 0.1 0.1 1.4 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 3.5 0.2 0.0 8.2 0.7 2.1 0.0 0.0 0.4 0.7 0.1 0.1 5.4 0.0 0.0 0.0 1.2 1.1 0.1 0.0 0.9 0.1 0.0 0.0 20.0 0.7 0.1 0.1 8.4 3.4 1.1 0.0 0.0 0.3 0.4 0.4 18.3 0.2 0.1 0.0 0.0 13.2 1.6 5.5 0.0 1.2 10.3 2.5 0.0 0.3 20.1 11.5 3.9 1.1 6.2 20.6 5.2 7.1 3.2 0.1 1.7 25.5 4.8 22.7 15.4 3.8 21.4 17.7 8.2 9.1 18.7 7.0 10.3 CSGALNACT2 "GALNACT-2, GALNACT2, MGC40204, PRO0082" ENSG00000169826 "Chondroitin sulfate N-acetylgalactosaminyltransferase 2" Q8N6G5 10 43138486-43185308 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 80.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031540 Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA031540: AB_10599943" "unprognostic (1.65e-1)" "unprognostic (2.70e-2)" "unprognostic (9.10e-2)" "unprognostic (6.41e-2)" "unprognostic (1.95e-1)" "unprognostic (8.28e-3)" "unprognostic (2.85e-3)" "unprognostic (4.95e-2)" "unprognostic (2.96e-1)" "unprognostic (3.43e-3)" "unprognostic (7.65e-2)" "unprognostic (1.90e-1)" "prognostic unfavourable (3.53e-7)" "unprognostic (2.68e-2)" "unprognostic (1.40e-1)" "unprognostic (2.47e-1)" "unprognostic (4.05e-3)" 18.3 8.2 9.0 16.4 13.0 80.6 11.5 10.0 10.9 11.4 12.5 17.6 4.8 6.8 14.7 7.5 9.8 12.8 18.4 11.5 10.0 9.0 8.2 11.3 24.0 25.7 11.0 6.2 16.2 6.3 7.8 15.0 18.3 11.5 10.4 8.9 19.8 7.9 8.6 12.5 8.1 9.6 15.7 14.4 21.1 8.7 6.7 9.6 24.3 9.2 6.6 12.2 17.8 11.0 2.5 11.6 15.2 16.3 8.7 6.3 5.1 4.8 3.2 6.1 5.8 9.5 16.1 1.5 17.8 24.0 7.9 12.4 1.1 5.1 8.1 4.4 16.0 4.5 5.0 6.7 12.9 9.7 3.7 4.2 3.1 3.3 20.9 9.7 8.9 16.0 7.4 17.5 36.8 10.0 1.7 24.3 16.1 2.5 7.3 5.8 2.6 4.3 4.6 6.1 3.4 6.9 2.6 5.5 10.9 4.6 4.8 11.1 6.3 8.0 14.8 6.8 10.8 21.2 11.9 6.3 8.8 4.3 14.4 23.9 3.1 10.7 9.8 15.2 6.3 11.4 5.5 2.5 4.9 4.9 11.6 2.2 5.8 4.8 9.0 8.7 16.3 3.4 5.6 5.1 9.0 13.0 10.0 10.9 10.0 9.0 11.0 6.2 11.5 9.6 CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782057-74803198 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 67.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011203, HPA026488, HPA028425" Approved Approved Approved Vesicles,Cytosol 1500000 "Vesicles, Cytosol" "CAB011203: AB_259070, HPA026488: AB_1847273, HPA028425: AB_10600899" "unprognostic (1.05e-1)" "prognostic favourable (5.14e-5)" "unprognostic (2.59e-3)" "prognostic favourable (8.22e-4)" "unprognostic (4.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "unprognostic (4.12e-2)" "unprognostic (4.61e-2)" "prognostic unfavourable (1.74e-4)" "prognostic favourable (1.07e-4)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" 9.3 8.0 9.5 39.3 11.0 19.9 12.6 18.7 13.4 12.1 13.5 11.8 7.3 16.1 13.9 6.4 33.3 10.6 11.2 14.0 9.8 8.5 8.0 20.9 15.6 67.2 11.1 7.4 10.5 6.7 6.6 10.4 8.8 12.2 9.8 8.9 9.8 13.2 7.0 8.7 14.9 26.2 8.5 10.9 62.7 13.1 8.1 10.6 62.7 8.1 9.5 47.4 17.4 13.2 35.6 22.8 49.6 46.8 16.3 30.7 19.9 12.7 18.0 8.8 14.5 8.4 6.5 7.6 8.6 8.2 16.3 11.6 16.4 11.8 57.1 11.4 7.7 13.3 18.5 17.3 4.6 27.6 22.8 48.3 6.6 16.5 11.7 25.2 61.6 9.2 8.5 11.6 10.4 12.3 13.9 19.9 9.7 21.5 18.1 14.9 10.9 12.9 20.1 7.6 41.6 7.5 28.4 14.7 10.2 11.1 23.4 14.8 16.1 37.2 10.6 19.8 10.4 15.5 14.8 10.7 21.5 58.3 10.2 48.2 13.3 20.7 19.7 49.6 23.4 42.4 20.0 29.4 20.3 23.1 22.8 35.6 15.7 18.4 39.1 16.3 46.8 13.2 30.7 19.9 9.5 11.0 18.7 13.4 9.8 8.5 11.1 7.4 12.2 10.6 CSNK1A1 "CK1, CK1a, CK1alpha, CKIa, CKIalpha" ENSG00000113712 "Casein kinase 1 alpha 1" P48729 5 149492197-149551552 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016680, HPA051334" Uncertain Supported Cytosol Cytosol "CAB016680: AB_1614518, HPA051334: " "unprognostic (4.27e-3)" "unprognostic (5.85e-3)" "prognostic favourable (1.15e-4)" "unprognostic (7.39e-2)" "unprognostic (2.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.27e-2)" "unprognostic (5.56e-2)" "unprognostic (4.38e-1)" "unprognostic (8.31e-2)" "prognostic unfavourable (5.79e-4)" "unprognostic (5.47e-2)" "unprognostic (1.56e-1)" "unprognostic (7.92e-2)" "unprognostic (4.41e-2)" "unprognostic (6.28e-3)" "unprognostic (6.92e-2)" 33.5 35.8 26.0 26.9 35.2 71.0 40.2 32.0 39.3 33.8 38.2 28.2 40.5 23.2 41.0 29.4 66.1 31.8 36.0 45.7 24.4 26.1 24.0 30.1 37.5 27.3 28.0 29.8 31.7 23.9 46.9 30.9 28.7 38.0 38.1 31.4 25.5 38.5 39.3 51.4 48.4 31.8 45.8 33.9 23.6 34.2 28.6 24.1 38.6 32.0 53.1 41.1 45.0 40.0 28.6 40.6 47.4 39.6 34.2 41.9 40.8 36.1 24.1 40.7 38.5 42.0 51.5 43.5 51.6 49.1 40.2 42.4 47.0 49.0 19.3 57.1 54.8 37.0 28.7 69.5 61.6 27.9 17.3 26.1 28.0 21.6 37.8 40.8 42.0 42.1 72.1 45.2 72.8 46.3 22.0 29.1 45.3 22.6 37.5 16.5 21.4 58.8 28.0 32.2 21.9 28.0 63.0 31.4 28.2 38.3 51.4 62.8 48.2 35.6 45.9 47.4 24.9 31.4 49.1 27.0 34.5 29.7 44.2 29.7 57.2 47.4 36.6 35.4 29.0 38.7 33.1 28.6 36.7 32.9 40.6 23.4 39.9 34.0 31.1 34.2 39.6 24.2 41.9 40.8 26.0 35.2 32.0 39.3 24.4 26.1 28.0 29.8 38.0 24.1 CSNK1A1L MGC33182 ENSG00000180138 "Casein kinase 1 alpha 1 like" Q8N752 13 37103259-37105664 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood: 10.5;testis: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 40 "neutrophil: 10.5" "Lineage enriched" "Detected in single" 42 "granulocytes: 10.5" HPA051334 Uncertain Cytosol Cytosol "HPA051334: " "unprognostic (1.23e-2)" "unprognostic (1.59e-1)" "unprognostic (3.19e-2)" "unprognostic (3.54e-2)" "unprognostic (2.40e-2)" "unprognostic (5.40e-2)" "unprognostic (8.90e-2)" "unprognostic (3.47e-1)" "unprognostic (1.47e-3)" "unprognostic (4.50e-1)" "unprognostic (2.02e-1)" "unprognostic (2.28e-3)" "unprognostic (3.45e-1)" "unprognostic (2.38e-1)" 0.0 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.0 0.0 0.0 0.0 0.0 0.1 0.2 10.5 0.2 0.1 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 10.5 0.1 0.2 0.1 0.2 0.2 CSNK1D "CKID, CKIdelta, HCKID" ENSG00000141551 "Casein kinase 1 delta" P48730 17 82239023-82273731 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015410 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "CAB015410: AB_831049" "unprognostic (1.07e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "prognostic unfavourable (7.04e-4)" "unprognostic (2.38e-2)" "unprognostic (3.43e-2)" "prognostic unfavourable (2.38e-6)" "unprognostic (8.05e-2)" "unprognostic (1.09e-1)" "unprognostic (5.00e-2)" "prognostic favourable (9.62e-5)" "unprognostic (2.23e-3)" "prognostic unfavourable (8.34e-4)" "unprognostic (3.54e-1)" "unprognostic (2.52e-1)" "unprognostic (5.52e-3)" "unprognostic (4.74e-2)" 30.1 36.3 30.8 25.9 30.8 21.0 26.3 36.3 42.8 30.9 33.0 27.7 32.9 32.6 37.9 29.8 31.3 38.0 34.9 28.5 26.2 26.9 32.0 33.5 30.1 25.8 27.2 27.8 31.4 42.8 34.2 35.9 32.8 30.3 35.3 19.3 28.4 38.0 37.7 52.3 26.7 42.3 34.1 21.4 36.4 32.5 48.3 24.6 29.2 33.0 31.8 33.7 31.4 26.1 6.4 11.4 29.6 12.1 8.7 7.6 7.1 21.3 25.4 14.5 19.9 19.1 20.4 29.1 31.4 19.8 22.5 21.1 20.8 18.4 19.5 24.8 22.3 20.7 13.6 31.8 18.2 16.5 32.9 24.2 20.2 22.3 55.5 19.9 18.5 30.9 22.6 15.3 22.8 32.8 27.2 10.4 21.2 24.9 25.5 20.8 15.5 40.0 22.0 17.9 17.3 23.7 33.5 17.9 32.3 37.5 31.3 35.1 22.4 26.1 34.5 32.4 29.1 28.1 23.8 22.7 11.0 20.9 26.0 17.1 23.5 4.7 11.0 14.6 7.6 12.1 7.4 6.4 5.9 7.3 11.4 5.6 5.0 5.3 29.6 8.7 11.1 5.5 5.2 7.1 30.8 30.8 36.3 42.8 26.2 26.9 27.2 27.8 30.3 24.6 CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 15.7" "Low lineage specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavourable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavourable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" 28.5 22.9 30.7 18.3 32.5 21.4 28.6 40.1 42.6 26.4 21.5 32.3 15.7 19.0 37.3 27.3 23.4 28.0 22.1 28.8 31.7 22.3 17.3 11.8 28.4 17.3 28.6 30.1 38.1 25.4 56.2 29.2 33.1 28.7 26.2 17.4 30.5 23.9 23.1 26.3 35.3 17.1 24.0 23.2 20.9 21.8 13.0 33.9 13.3 21.4 14.2 17.4 25.5 28.8 3.7 15.7 4.8 1.8 5.9 4.0 1.2 23.3 11.4 31.0 29.7 15.5 23.8 23.3 30.5 39.1 27.8 27.0 14.6 18.3 17.6 13.3 28.8 20.0 23.5 42.2 20.2 28.1 51.1 5.6 37.7 11.2 32.0 12.3 15.0 22.7 35.8 42.3 57.3 29.5 12.4 36.4 26.8 15.6 17.1 15.1 22.7 16.5 32.0 22.2 27.6 25.5 19.6 45.9 18.0 26.0 27.0 30.5 13.8 17.9 33.5 25.2 27.5 14.5 24.3 16.3 23.3 24.8 37.4 13.9 42.2 3.8 1.8 3.4 3.4 0.8 4.0 2.5 3.8 3.4 1.8 3.7 2.1 3.1 4.8 5.9 0.6 15.7 1.7 1.2 30.7 32.5 40.1 38.8 31.7 22.3 28.6 30.1 28.7 33.9 CSNK1G1 CK1gamma1 ENSG00000169118 "Casein kinase 1 gamma 1" Q9HCP0 15 64165517-64356259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018209 Supported Cytosol Cytosol "HPA018209: AB_1847278" "unprognostic (9.10e-2)" "unprognostic (8.09e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (1.61e-2)" "unprognostic (2.02e-1)" "unprognostic (8.63e-2)" "unprognostic (3.75e-2)" "unprognostic (7.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.31e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" 7.2 7.8 10.2 11.9 15.1 11.6 8.7 12.2 10.6 8.7 7.4 7.6 11.6 7.0 11.1 9.9 15.7 10.8 7.8 5.6 8.9 7.6 8.6 6.0 8.4 9.6 6.6 4.7 8.5 8.8 10.4 16.1 7.2 7.2 6.8 7.9 10.1 8.2 14.5 6.5 10.4 6.8 11.1 5.3 8.2 6.8 41.3 7.3 11.8 11.5 5.6 11.2 8.3 10.6 4.1 4.1 8.8 5.1 5.3 8.0 2.4 5.1 10.7 7.8 10.1 6.7 9.1 7.1 6.3 6.5 10.7 9.7 8.5 10.0 8.0 3.4 9.9 11.7 20.3 12.7 12.6 15.2 5.2 7.4 8.6 5.7 7.7 13.8 8.9 8.1 16.9 10.9 15.7 11.7 9.0 8.4 9.6 7.0 7.0 4.3 7.2 5.6 11.8 9.7 6.4 8.6 20.4 12.5 7.6 8.3 5.0 7.3 8.7 5.4 12.6 9.8 11.7 7.7 7.7 9.7 18.6 6.8 9.1 10.2 6.0 0.9 3.6 5.6 5.7 5.1 8.0 3.6 5.1 4.1 2.7 4.1 5.1 4.7 8.8 5.3 4.3 4.1 3.9 2.4 10.2 15.1 12.2 10.6 8.9 7.6 6.6 4.7 7.2 7.3 CSNK1G2 CK1g2 ENSG00000133275 "Casein kinase 1 gamma 2" P78368 19 1941149-1981338 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034868, HPA056572" Uncertain Approved Vesicles Vesicles "HPA034868: AB_10671235, HPA056572: " "unprognostic (2.00e-1)" "unprognostic (2.15e-1)" "unprognostic (1.83e-1)" "unprognostic (2.42e-3)" "unprognostic (6.51e-3)" "unprognostic (2.27e-3)" "unprognostic (1.14e-3)" "unprognostic (2.00e-1)" "unprognostic (9.42e-2)" "unprognostic (5.78e-2)" "unprognostic (4.83e-3)" "unprognostic (4.09e-3)" "unprognostic (7.95e-2)" "unprognostic (4.65e-3)" "unprognostic (5.09e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-2)" 18.7 22.2 24.8 34.9 19.5 38.1 16.7 30.8 28.9 14.1 19.0 18.2 18.9 27.0 16.5 19.0 22.1 16.9 20.4 16.0 23.3 18.3 19.3 17.9 21.8 35.1 17.3 21.2 18.6 27.0 11.4 24.4 16.7 18.7 18.7 8.7 19.7 26.6 16.0 29.0 23.3 22.1 15.1 12.7 39.1 24.1 58.5 17.4 20.6 16.5 18.1 32.2 17.1 17.1 4.0 5.9 11.2 14.1 3.5 4.9 2.3 23.2 12.5 17.5 27.4 6.1 11.6 14.6 14.4 9.6 11.0 13.6 10.3 12.8 14.7 12.2 9.2 16.8 9.4 17.6 4.9 13.3 20.4 10.4 20.5 17.4 9.9 16.5 26.3 11.4 11.6 11.5 7.4 13.1 21.6 50.5 7.2 13.6 32.8 21.7 31.7 14.1 28.5 11.1 23.8 8.3 24.6 28.2 23.2 11.0 18.1 16.0 11.5 27.2 15.6 14.0 11.0 29.2 16.8 32.6 17.3 18.0 14.1 15.7 14.6 2.8 4.0 5.0 4.9 6.2 3.5 3.9 3.6 4.2 3.9 4.0 2.9 4.1 11.2 3.5 14.1 5.9 2.5 2.3 24.8 19.5 30.8 28.9 23.3 18.3 17.3 21.2 18.7 17.4 CSNK1G3 ENSG00000151292 "Casein kinase 1 gamma 3" Q9Y6M4 5 123512099-123617045 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027010 Approved "HPA027010: AB_10602803" "unprognostic (1.28e-1)" "unprognostic (1.88e-1)" "prognostic favourable (9.90e-5)" "unprognostic (1.60e-2)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.92e-3)" "unprognostic (4.92e-1)" "unprognostic (1.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.52e-1)" "unprognostic (1.97e-3)" "unprognostic (4.38e-1)" 20.7 15.0 15.5 21.7 22.7 11.1 37.7 23.7 31.7 18.8 24.0 8.6 11.2 23.5 19.4 18.4 18.8 14.6 17.7 14.0 22.2 18.0 16.2 27.7 29.0 21.8 13.3 17.7 18.7 15.8 18.6 18.1 16.2 16.6 13.2 27.4 9.1 15.3 14.1 15.6 13.4 24.9 18.6 16.1 16.5 18.2 16.4 11.4 17.2 16.2 16.5 17.4 21.9 18.2 13.6 5.3 11.3 5.9 12.7 9.5 5.1 12.9 12.5 18.8 17.8 19.2 21.5 9.3 14.1 16.9 15.7 23.5 11.2 20.8 0.0 18.4 16.9 9.5 15.1 27.9 27.1 19.6 10.3 9.2 14.5 11.8 17.1 4.8 9.5 18.2 18.2 17.6 33.5 17.0 5.1 10.6 13.2 9.0 6.4 5.9 10.6 8.6 7.3 19.9 12.4 11.7 14.3 16.4 11.9 15.7 10.4 22.9 13.6 13.5 15.6 23.1 17.5 14.0 15.5 11.9 13.0 11.7 13.8 13.9 14.9 11.3 5.8 2.5 7.1 5.6 9.5 13.6 5.9 6.2 5.3 12.9 6.1 6.4 4.6 12.7 5.9 4.7 7.3 5.1 15.5 22.7 23.7 31.7 22.2 18.0 13.3 17.7 16.6 11.4 CSNK2A1 "Cka1, Cka2" ENSG00000101266 "Casein kinase 2 alpha 1" P68400 20 472498-543835 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB020680, HPA059206, HPA061698, CAB069395" Supported Supported Nucleoplasm Nucleoplasm "CAB020680: , CAB069395: AB_1611912, HPA059206: , HPA061698: " "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (5.44e-2)" "unprognostic (8.28e-3)" "unprognostic (3.62e-2)" "unprognostic (2.04e-2)" "prognostic unfavourable (4.11e-6)" "unprognostic (4.08e-2)" "unprognostic (3.89e-1)" "unprognostic (6.88e-2)" "unprognostic (1.94e-2)" "unprognostic (1.16e-1)" "unprognostic (8.58e-2)" "unprognostic (1.50e-1)" "unprognostic (4.47e-1)" "unprognostic (9.53e-2)" "unprognostic (7.37e-2)" 21.5 26.7 23.2 20.6 31.3 16.7 24.1 26.3 32.8 22.2 26.1 28.2 19.5 21.9 24.3 15.7 31.9 23.3 17.7 29.2 21.8 21.9 24.5 23.1 18.6 21.9 21.3 22.6 24.9 27.5 27.7 24.6 23.1 29.4 20.7 24.2 19.6 23.8 22.4 58.8 27.0 22.5 23.3 21.3 21.8 26.5 51.6 23.2 30.3 22.4 22.4 25.7 26.2 22.8 19.8 25.4 23.3 27.3 18.7 19.4 15.7 43.6 39.0 35.9 22.1 13.8 24.0 23.3 25.6 25.9 29.7 33.1 39.2 28.6 39.0 16.4 21.0 33.9 39.5 38.3 42.4 13.6 14.3 52.7 10.4 37.9 23.6 45.8 11.7 22.0 40.6 27.3 76.2 32.0 51.7 25.6 27.1 14.4 55.0 16.3 51.5 26.8 32.7 31.5 31.7 25.6 27.6 37.7 30.0 21.9 42.2 38.9 28.1 18.0 30.1 31.6 27.1 20.4 37.9 26.6 62.8 38.4 15.8 27.5 31.8 23.3 19.7 22.2 16.1 27.3 19.4 19.8 15.7 15.5 25.4 18.9 16.0 15.0 12.1 18.7 25.2 21.1 16.4 15.7 23.2 31.3 26.3 32.8 21.8 21.9 21.3 22.6 29.4 23.2 CSNK2A3 CSNK2A1P ENSG00000254598 "Casein kinase 2 alpha 3" Q8NEV1 11 11351942-11353357 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 5.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "HPA059206, HPA061698" Uncertain Approved Nucleoplasm Nucleoplasm "HPA059206: , HPA061698: " "unprognostic (3.10e-2)" "unprognostic (3.39e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.82e-2)" "unprognostic (1.60e-1)" "unprognostic (6.25e-4)" "unprognostic (4.36e-2)" "unprognostic (5.42e-2)" "unprognostic (1.88e-1)" "unprognostic (5.46e-3)" "unprognostic (1.07e-1)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.38e-2)" 4.6 1.6 1.3 2.8 1.3 0.6 1.9 1.6 5.5 2.8 3.8 0.5 2.1 3.4 1.8 3.8 3.4 1.1 1.6 2.3 1.5 1.2 5.4 3.0 3.7 1.0 1.1 0.7 2.0 1.4 0.6 1.7 2.9 2.0 2.2 0.7 2.1 1.7 3.6 5.3 1.9 2.9 2.9 1.2 0.9 1.3 3.5 0.3 3.6 1.6 1.8 2.7 1.8 1.3 0.7 0.9 1.1 0.6 0.8 1.0 1.2 5.5 1.1 0.2 2.1 0.0 0.0 0.7 0.5 0.3 0.3 0.3 0.0 0.3 0.0 0.4 0.0 1.8 0.9 0.8 0.0 0.2 0.3 0.0 0.2 0.5 0.0 0.2 0.3 0.6 0.4 0.0 0.6 0.0 0.4 0.8 0.7 0.6 1.3 0.7 1.7 3.0 0.9 0.2 1.0 0.6 1.0 0.4 1.2 1.6 3.1 0.6 1.2 0.4 0.7 0.9 1.1 0.4 0.6 0.4 0.9 0.8 2.6 0.2 2.5 0.7 0.5 1.1 0.6 0.6 0.9 0.7 0.4 0.7 0.9 0.7 1.0 0.3 0.1 0.8 0.6 0.7 0.7 1.2 1.3 1.3 1.6 5.5 1.5 1.2 1.1 0.7 2.0 0.3 CTDNEP1 "DULLARD, HSA011916, NET56" ENSG00000175826 "CTD nuclear envelope phosphatase 1" O95476 17 7243591-7252491 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 140.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037439, HPA066466" Uncertain Approved "Lipid droplets" "Lipid droplets" "HPA037439: AB_10601264, HPA066466: " "unprognostic (7.11e-2)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "prognostic favourable (6.45e-4)" "unprognostic (3.12e-1)" "unprognostic (2.13e-1)" "unprognostic (4.61e-2)" "unprognostic (1.50e-2)" "unprognostic (2.98e-1)" "unprognostic (9.90e-2)" "prognostic favourable (1.81e-4)" "unprognostic (3.37e-1)" "unprognostic (2.77e-3)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (9.97e-2)" "unprognostic (2.02e-2)" 27.1 23.1 21.4 22.4 21.0 24.2 38.8 21.8 26.6 25.3 24.8 26.6 16.7 20.8 31.2 22.8 26.6 27.3 18.8 29.0 21.5 12.9 23.8 20.6 26.5 39.4 24.7 17.1 31.1 27.9 30.7 26.1 30.4 20.5 25.2 27.9 20.4 23.0 23.8 140.1 35.5 30.9 26.7 25.6 38.3 24.3 26.6 24.3 43.8 26.0 31.5 34.1 22.4 26.7 13.0 17.3 18.3 11.8 7.2 11.2 3.8 38.1 57.2 32.2 34.5 50.4 62.1 24.4 28.6 48.0 46.2 39.8 27.3 26.7 35.4 30.5 51.1 32.0 42.2 44.1 51.6 52.5 35.8 24.7 38.4 46.9 46.8 28.1 46.8 50.0 53.7 52.8 56.4 49.1 22.0 26.3 43.3 24.1 31.3 30.1 22.4 24.3 38.1 28.7 28.2 36.7 20.1 12.4 35.5 22.8 22.9 30.5 21.5 23.2 27.9 33.7 29.0 26.9 53.7 22.7 19.8 18.2 43.4 38.8 34.8 6.3 11.8 18.3 10.5 11.7 8.5 13.0 10.1 11.0 8.4 12.4 7.8 11.2 15.6 7.2 7.7 17.3 9.6 3.8 21.4 21.0 21.8 26.6 21.5 12.9 24.7 17.1 20.5 24.3 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679801-79756623 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 6.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: " "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favourable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favourable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 10.6 8.2 6.2 12.8 9.5 21.8 9.5 7.5 12.2 7.9 12.0 14.4 5.3 13.4 11.9 9.3 11.4 9.8 10.0 6.6 6.8 5.7 8.9 13.4 10.2 14.4 12.3 5.1 7.7 13.4 4.6 7.9 10.6 9.1 9.1 6.2 8.4 10.6 8.3 12.1 20.9 13.8 8.2 6.8 15.3 12.2 27.2 10.6 26.2 9.4 8.8 14.8 11.4 8.9 0.7 1.5 6.4 1.0 2.4 2.0 0.5 8.0 9.0 5.0 7.2 4.0 3.4 16.7 5.4 4.0 5.0 4.9 5.9 5.1 10.3 2.5 3.5 9.9 4.3 5.7 2.1 9.5 7.7 5.3 4.5 8.0 5.9 23.4 13.2 5.6 5.4 5.3 2.5 6.0 6.5 5.3 1.9 7.2 15.7 18.4 7.9 12.1 12.2 6.6 12.4 3.7 8.4 7.8 8.1 6.4 6.4 8.6 5.2 13.8 8.1 8.6 12.5 3.4 5.8 4.4 16.5 10.2 7.3 11.8 6.0 0.0 1.0 6.4 1.3 0.9 1.1 0.7 1.0 2.0 1.5 0.4 1.3 0.7 2.7 2.4 0.9 0.2 0.3 0.5 6.2 9.5 7.5 12.2 6.8 5.7 12.3 5.1 9.1 10.6 CTDSP1 "NLIIF, SCP1" ENSG00000144579 "CTD small phosphatase 1" Q9GZU7 2 218398256-218405941 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062654 Supported Nucleoplasm Nucleoplasm "HPA062654: " "unprognostic (1.97e-2)" "unprognostic (4.02e-2)" "unprognostic (1.67e-3)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (3.90e-2)" "unprognostic (8.69e-2)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (3.70e-1)" "unprognostic (1.79e-1)" "unprognostic (2.58e-1)" "unprognostic (6.67e-2)" "unprognostic (2.62e-1)" "unprognostic (7.01e-2)" "unprognostic (1.57e-1)" 32.9 22.5 15.9 21.9 13.9 19.9 41.1 12.2 16.4 34.8 30.7 27.6 31.8 24.2 34.5 30.7 31.3 30.9 43.4 25.9 15.5 8.6 34.1 47.5 30.2 33.2 15.0 13.1 44.9 50.8 28.8 12.6 71.3 15.9 41.5 19.8 35.4 34.3 31.5 23.2 30.5 41.3 33.7 12.4 39.1 34.2 15.1 16.1 33.2 41.0 27.2 29.9 32.5 28.4 3.4 6.6 29.3 12.4 6.7 11.0 7.5 10.1 13.1 7.8 25.5 21.1 19.7 29.3 13.7 19.8 13.3 11.5 17.1 25.5 6.2 11.9 24.2 20.9 11.5 16.5 6.8 22.0 9.0 23.5 16.1 22.9 25.4 14.4 32.9 22.4 20.2 10.1 11.4 19.5 19.0 22.1 14.0 28.5 12.6 42.1 5.4 13.5 17.5 10.9 13.3 16.9 12.6 5.2 12.9 12.0 26.1 12.9 14.4 34.7 17.0 21.2 12.9 16.1 6.0 14.2 9.2 14.5 18.8 13.7 11.7 20.3 12.4 29.3 11.0 10.2 7.1 3.4 6.7 7.0 6.6 3.2 4.3 5.7 24.5 6.7 10.4 2.3 5.6 7.5 15.9 13.9 12.2 16.4 15.5 8.6 15.0 13.1 15.9 16.1 CTDSP2 "OS4, PSR2, SCP2" ENSG00000175215 "CTD small phosphatase 2" O14595 12 57819927-57846739 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "RH-30: 165.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052607 Uncertain Approved Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA052607: " "unprognostic (7.09e-2)" "unprognostic (2.45e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (4.39e-1)" "unprognostic (5.57e-2)" "unprognostic (1.05e-3)" "unprognostic (2.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" "unprognostic (1.12e-1)" "unprognostic (4.15e-1)" "unprognostic (7.38e-3)" "unprognostic (5.50e-2)" "unprognostic (6.50e-2)" "unprognostic (2.18e-1)" "unprognostic (3.11e-1)" 44.5 43.6 28.2 31.6 34.8 17.6 39.6 57.1 33.4 49.0 48.4 36.7 47.7 24.4 50.4 32.9 38.0 41.9 37.7 34.6 31.2 16.5 32.8 32.6 51.3 31.3 37.1 19.9 52.5 53.9 33.7 25.4 42.9 31.0 40.5 38.6 29.3 45.8 60.9 48.8 39.9 36.1 44.1 25.7 38.1 43.1 21.0 40.9 62.9 40.1 32.8 33.9 46.1 63.0 7.3 9.3 18.7 9.7 8.2 11.5 7.1 10.8 4.7 22.6 14.4 20.4 35.2 7.5 11.7 22.3 11.7 10.4 6.0 17.7 13.3 13.5 25.0 8.7 9.4 11.4 12.3 4.5 4.0 18.4 7.2 4.8 19.0 8.3 10.7 33.6 12.2 10.6 9.0 18.2 9.6 23.6 5.8 5.0 8.9 5.0 11.5 6.0 11.9 165.7 17.4 9.1 15.8 4.2 9.4 16.4 9.4 14.1 17.1 14.6 14.6 10.4 11.4 11.7 4.1 7.0 7.5 16.0 11.7 7.7 8.0 11.5 9.7 14.7 6.9 9.0 8.2 7.3 9.9 8.0 9.3 6.5 11.5 8.7 18.7 8.2 7.7 7.7 6.4 7.1 28.2 34.8 57.1 33.4 31.2 16.5 37.1 19.9 31.0 40.9 CTDSPL "C3orf8, HYA22, PSR1, RBSP3, SCP3" ENSG00000144677 "CTD small phosphatase like" O15194 3 37861960-37984469 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048325 Approved Approved Nucleoplasm,Vesicles 10000 Vesicles Nucleoplasm "HPA048325: " "unprognostic (7.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (6.48e-3)" "unprognostic (1.73e-1)" "unprognostic (3.35e-2)" "unprognostic (1.66e-3)" "unprognostic (4.30e-2)" "unprognostic (1.96e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-3)" "unprognostic (1.20e-1)" "prognostic favourable (6.22e-14)" "unprognostic (3.48e-2)" "unprognostic (6.84e-2)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" 12.8 6.3 11.1 7.8 12.4 5.6 22.0 30.2 14.1 15.5 19.9 8.0 25.7 9.3 14.5 18.3 16.8 12.2 37.2 18.9 13.1 5.9 26.7 13.3 19.0 4.9 7.8 9.9 13.7 10.2 8.3 9.4 20.6 6.9 17.5 20.3 15.6 45.5 22.4 12.5 34.8 11.2 21.3 8.1 11.3 19.7 8.1 8.3 2.9 10.0 13.9 6.9 19.6 21.7 0.0 0.2 1.1 0.5 0.0 0.5 5.6 15.5 6.8 2.8 8.8 11.0 15.9 20.9 10.7 13.5 7.4 8.8 9.8 12.8 0.0 6.6 13.2 13.0 6.9 20.3 6.0 0.0 5.4 9.5 7.2 22.1 10.1 0.0 2.3 8.2 49.9 7.8 9.4 10.4 3.0 0.0 12.3 4.9 3.9 0.0 11.5 1.0 4.3 5.4 0.1 23.8 10.4 2.3 7.4 5.9 10.6 11.9 10.2 2.6 8.2 5.4 7.5 10.0 6.7 0.2 0.0 0.0 6.0 5.3 9.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 1.1 0.0 0.0 0.0 0.0 5.6 11.1 12.4 30.2 14.1 13.1 5.9 7.8 9.9 6.9 8.3 CTH ENSG00000116761 "Cystathionine gamma-lyase" P32929 1 70411218-70439851 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" "Calmodulin-binding, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 104.5" "Cell line enhanced" "Detected in many" "HHSteC: 19.7;Karpas-707: 30.6;SK-MEL-30: 40.0" "Group enriched" "Detected in all" 5 "liver cancer: 30.0;testis cancer: 8.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.5;T-cells: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021591, HPA023300" Enhanced 25000 "HPA021591: AB_1847321, HPA023300: AB_1847322" "unprognostic (3.41e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (2.76e-1)" "unprognostic (7.66e-2)" "unprognostic (2.45e-3)" "prognostic favourable (8.69e-4)" "unprognostic (1.71e-1)" "unprognostic (1.95e-1)" "unprognostic (1.00e-1)" "unprognostic (1.43e-3)" "unprognostic (5.05e-3)" "unprognostic (3.25e-2)" "unprognostic (1.03e-1)" "unprognostic (8.97e-2)" "unprognostic (3.05e-3)" "unprognostic (1.26e-1)" 2.2 8.3 2.3 1.0 3.2 2.2 2.0 3.7 3.6 1.9 3.3 2.2 1.8 3.3 1.7 1.4 2.7 2.3 1.5 1.6 2.1 2.7 8.2 104.5 2.2 1.0 2.4 2.2 18.3 11.6 1.5 1.7 1.0 3.2 2.9 4.1 11.2 4.8 2.8 2.1 1.0 3.2 1.2 2.4 0.8 3.7 5.4 1.3 0.0 11.4 1.2 1.5 2.7 1.2 4.5 1.3 1.1 0.6 0.6 6.4 1.1 5.0 0.7 3.4 4.8 4.2 2.4 7.6 2.0 1.8 1.7 7.6 1.4 3.1 2.7 1.6 1.4 2.4 13.3 1.4 3.5 8.4 2.9 3.2 2.5 4.3 19.7 3.7 0.8 3.7 11.9 3.6 4.2 1.5 6.4 30.6 1.1 1.4 1.3 0.8 3.5 2.7 1.3 1.8 7.7 3.5 0.0 1.9 1.6 3.2 3.8 40.0 1.3 2.0 0.5 0.5 3.9 2.7 1.9 11.8 6.9 1.4 4.7 7.5 1.3 1.1 0.6 0.2 2.5 0.4 4.6 4.5 2.3 3.5 1.0 2.9 6.4 3.1 0.9 0.6 0.5 1.3 0.7 1.1 2.3 3.2 3.7 3.6 2.1 2.7 2.4 2.2 3.2 1.3 CTPS1 "CTPS, GATD5" ENSG00000171793 "CTP synthase 1" P17812 1 40979335-41012565 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Immunity, Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017111, HPA051322" Enhanced Supported "Actin filaments,Cytosol" "Actin filaments, Cytosol" "CAB017111: , HPA051322: " "unprognostic (6.60e-2)" "unprognostic (4.44e-2)" "unprognostic (3.21e-2)" "unprognostic (2.00e-3)" "unprognostic (2.14e-1)" "unprognostic (8.37e-2)" "unprognostic (1.42e-2)" "unprognostic (9.72e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (2.04e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-1)" "unprognostic (8.21e-3)" "unprognostic (1.34e-1)" "unprognostic (4.49e-1)" "unprognostic (1.89e-2)" 7.1 10.0 4.5 10.8 7.8 9.7 5.1 5.9 9.8 14.4 23.6 5.8 16.3 4.3 25.9 8.4 11.3 21.9 13.4 6.7 4.7 5.1 8.6 26.4 7.0 9.4 7.9 4.7 10.1 6.3 16.8 5.4 7.7 6.2 14.4 9.8 9.1 56.5 19.6 13.2 5.8 13.5 35.8 5.1 7.5 9.0 11.8 6.7 14.6 4.5 11.3 13.2 21.3 9.5 6.0 12.8 0.0 7.3 6.6 7.0 3.8 21.1 19.4 27.5 22.1 7.6 9.5 43.2 37.2 16.0 40.9 27.6 38.1 18.8 39.7 16.9 17.0 15.0 29.4 27.8 40.9 16.6 22.3 24.3 25.9 12.0 24.9 32.4 19.1 10.4 15.1 42.3 30.4 18.6 24.4 17.5 28.6 11.9 35.0 12.1 37.5 23.1 27.0 33.4 25.7 20.7 19.3 36.9 18.0 23.2 25.0 9.2 8.7 44.8 15.2 27.1 35.4 18.2 46.2 11.3 13.2 35.3 17.7 25.8 28.1 0.0 4.0 0.0 4.6 7.3 6.6 6.0 5.3 4.8 12.0 3.9 4.4 7.0 0.0 6.6 6.1 12.8 6.6 3.8 4.5 7.8 5.9 9.8 4.7 5.1 7.9 4.7 6.2 6.7 CTPS2 ENSG00000047230 "CTP synthase 2" Q9NRF8 X 16588003-16712936 "Enzymes, Predicted intracellular proteins" "Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017437 Uncertain Approved Nucleoplasm,Cytosol 14000 "Nucleoplasm, Cytosol" "HPA017437: AB_1847326" "unprognostic (1.40e-1)" "unprognostic (6.69e-2)" "unprognostic (3.37e-2)" "unprognostic (7.38e-2)" "unprognostic (1.05e-2)" "unprognostic (2.11e-1)" "prognostic unfavourable (2.37e-5)" "unprognostic (6.57e-3)" "unprognostic (8.52e-2)" "unprognostic (4.31e-3)" "unprognostic (4.43e-1)" "unprognostic (1.89e-2)" "unprognostic (7.22e-2)" "unprognostic (6.04e-2)" "unprognostic (8.93e-2)" "unprognostic (5.04e-2)" "prognostic favourable (4.56e-4)" 10.0 12.0 7.8 11.5 11.9 7.8 13.5 14.3 9.9 17.5 13.3 14.8 10.8 15.6 22.0 10.2 9.6 12.1 11.9 7.2 8.6 7.1 8.1 13.4 8.3 7.9 9.1 6.1 17.9 14.9 22.9 8.5 8.3 9.3 12.8 12.6 14.1 11.8 9.7 5.5 9.2 12.8 14.0 12.3 7.1 11.3 4.4 10.8 11.5 11.8 8.4 10.6 11.8 11.2 1.6 3.3 1.1 6.1 3.8 2.4 1.4 7.5 6.9 11.3 9.4 5.8 4.4 0.1 4.2 3.5 6.8 6.2 7.0 7.9 0.2 13.3 4.3 6.1 15.9 7.6 8.1 0.0 10.5 4.3 9.7 10.1 3.0 3.0 0.1 4.8 2.6 6.3 5.4 9.0 6.1 0.3 6.1 10.0 0.1 2.4 19.4 8.1 0.1 6.5 2.3 7.2 8.5 7.1 13.0 13.2 1.0 7.6 18.3 8.8 5.8 3.5 1.9 9.3 3.6 0.2 0.1 25.1 2.8 2.7 3.9 0.4 1.5 1.1 1.3 0.8 2.4 1.6 2.2 1.4 3.3 1.4 1.7 1.7 0.1 3.8 6.1 2.2 2.0 1.4 7.8 11.9 14.3 9.9 8.6 7.1 9.1 6.1 9.3 10.8 CTRC "CLCR, ELA4" ENSG00000162438 "Chymotrypsin C" Q99895 1 15438439-15449242 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 417 "pancreas: 1443.7" "Cell line enhanced" "Detected in some" "A-431: 3.6" "Cancer enriched" "Detected in some" 168 "pancreatic cancer: 236.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA046920 Enhanced "Secreted to digestive system" "HPA046920: " "unprognostic (2.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (8.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (2.94e-2)" "unprognostic (7.60e-2)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-11)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "unprognostic (5.99e-3)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 1443.7 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.4 3.4 0.7 1.5 0.6 0.1 3.6 0.6 0.5 0.7 0.2 0.0 0.2 0.3 0.4 0.0 0.0 0.0 1.7 0.5 1.1 0.0 0.5 0.0 0.1 0.2 1.1 0.5 0.4 0.3 0.1 0.9 0.2 1.7 0.2 0.0 0.0 0.0 0.0 0.1 1.7 0.2 0.5 1.0 1.6 0.4 0.0 0.5 0.1 0.3 0.0 0.1 0.4 1.0 0.4 0.2 0.2 0.3 0.1 0.9 0.4 1.4 0.9 0.2 0.8 1.6 0.3 0.8 0.8 0.3 3.4 0.4 0.4 0.4 0.2 0.2 0.3 0.3 0.6 0.1 1.1 0.3 0.4 1.7 1.5 0.7 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CTRL ENSG00000141086 "Chymotrypsin like" P40313 16 67927640-67932414 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 281 "pancreas: 639.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034504, HPA034505" Enhanced "Secreted to digestive system" "HPA034504: AB_2674196, HPA034505: AB_10602212" "unprognostic (3.03e-5)" "unprognostic (3.53e-3)" "unprognostic (3.46e-2)" "unprognostic (1.37e-1)" "unprognostic (9.66e-2)" "unprognostic (2.00e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (6.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.88e-1)" "unprognostic (3.20e-4)" "unprognostic (6.69e-2)" "unprognostic (2.79e-1)" "unprognostic (2.63e-1)" "unprognostic (1.29e-3)" 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 639.8 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.6 1.1 1.1 0.7 0.0 2.2 0.5 0.5 3.7 1.1 0.3 0.2 0.1 1.8 0.3 0.7 1.1 1.3 2.3 1.4 0.7 0.4 0.7 1.0 5.6 0.7 3.1 1.4 6.3 0.7 1.1 1.4 0.3 0.9 2.5 1.2 0.2 3.9 1.0 0.0 1.5 1.0 0.6 1.0 0.7 2.7 6.2 2.2 2.8 0.5 4.5 0.0 0.9 2.6 1.4 1.3 0.7 0.6 1.2 4.3 1.6 0.1 2.0 0.5 1.6 6.5 2.7 3.6 0.2 0.8 0.8 0.6 0.7 0.3 1.5 0.7 0.2 0.3 1.1 0.5 0.9 0.6 0.5 2.2 1.1 0.0 0.7 1.1 0.0 0.5 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898820 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 125.7" "Cell line enhanced" "Detected in all" "ASC diff: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068" Enhanced Enhanced Vesicles "Intracellular and membrane" 18000000 Vesicles "CAB024930: , HPA031068: AB_10601205" "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavourable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" 29.0 125.7 12.0 22.8 19.5 22.1 35.3 11.4 30.0 14.1 50.6 17.4 16.2 29.4 18.2 19.3 20.7 12.7 28.0 32.6 11.5 11.6 88.2 43.8 28.4 38.9 12.3 16.1 23.9 19.2 28.3 16.5 47.7 15.7 18.2 50.5 30.1 20.5 15.1 19.3 28.2 40.6 19.6 11.9 38.8 19.7 14.3 11.2 8.0 18.1 24.9 22.4 23.3 18.7 7.0 16.6 81.1 46.1 12.0 31.2 50.0 14.4 14.9 2.8 12.7 116.2 60.2 6.4 20.8 55.4 22.8 29.7 27.9 38.9 3.1 24.1 38.9 23.1 7.5 14.0 14.3 6.0 7.0 8.2 10.4 48.6 25.9 13.0 33.9 47.8 16.9 14.7 3.3 24.8 8.1 47.8 24.7 29.7 3.3 12.0 2.8 35.4 5.2 14.5 17.2 18.2 12.7 5.6 5.3 34.6 60.6 58.0 14.8 18.7 22.8 45.8 10.7 25.9 16.3 23.6 29.7 2.2 82.5 17.3 18.8 60.6 46.1 81.1 7.5 26.6 31.2 7.0 12.9 13.2 16.6 3.6 4.7 6.9 24.7 12.0 17.7 6.6 23.9 50.0 12.0 19.5 11.4 30.0 11.5 11.6 12.3 16.1 15.7 11.2 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869448 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 297.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 237.0;fHDF/TERT166: 137.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 53.1;classical monocyte: 127.4;intermediate monocyte: 97.0;myeloid DC: 68.0;non-classical monocyte: 54.7;plasmacytoid DC: 95.4" "Group enriched" "Detected in all" 5 "dendritic cells: 95.4;granulocytes: 53.1;monocytes: 127.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" 130000000 Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favourable (5.76e-4)" "prognostic unfavourable (9.02e-4)" 227.9 42.1 19.6 67.2 24.4 14.7 67.6 14.9 31.4 76.7 49.1 30.1 22.7 29.9 53.2 44.8 54.2 52.4 43.6 120.7 18.3 23.7 95.6 167.8 94.3 175.1 29.1 16.5 44.2 31.6 13.8 21.6 68.7 24.8 42.6 27.9 33.8 63.7 33.6 41.3 22.8 51.2 51.1 35.9 116.4 26.7 21.5 20.4 18.1 297.0 25.9 38.4 56.8 62.2 7.9 95.4 53.1 127.4 5.3 17.1 108.5 6.4 29.1 3.7 16.0 65.8 74.1 11.6 121.4 237.0 42.5 50.4 13.9 37.9 0.1 17.6 137.7 35.4 5.1 33.5 26.9 3.1 5.0 9.4 3.4 34.1 67.0 2.1 7.0 81.1 45.7 38.4 34.4 83.1 7.8 21.5 35.3 5.1 0.8 3.4 3.1 9.8 3.3 3.8 16.4 12.9 10.1 1.6 9.5 14.0 7.6 63.3 12.3 6.3 115.1 72.3 24.5 23.1 22.6 21.4 15.5 0.5 82.9 8.1 33.8 53.1 127.4 16.3 5.2 97.0 7.2 7.9 17.1 5.8 68.0 6.1 9.6 4.1 18.5 5.3 54.7 95.4 13.4 108.5 19.6 24.4 14.9 28.0 18.3 23.7 29.1 16.5 24.8 20.4 CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88293592-88337787 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 218.6" "Cell line enhanced" "Detected in all" "BJ hTERT+: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" 19000000 Vesicles "CAB025364: , HPA066610: , HPA068434: " "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavourable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favourable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" 40.7 20.5 6.7 44.5 10.6 12.0 35.3 1.5 5.6 14.0 25.3 7.1 6.2 20.4 16.1 24.0 21.8 16.7 36.6 53.3 6.8 6.5 62.7 18.1 110.1 218.6 12.5 3.6 11.0 24.8 3.8 17.3 43.4 9.4 13.8 33.1 27.0 35.1 5.8 10.0 11.7 28.5 14.2 14.6 86.6 13.5 10.8 9.2 19.5 17.7 25.3 30.0 30.2 16.9 8.5 75.9 52.5 92.6 34.7 42.4 31.2 11.2 11.5 4.5 9.4 12.2 33.0 30.2 77.1 112.0 44.0 31.8 31.2 51.8 17.5 41.0 41.8 18.2 7.0 32.6 35.2 30.8 12.7 22.8 31.9 35.1 16.2 28.9 15.4 45.9 23.1 33.9 69.6 43.2 20.7 21.1 5.3 2.1 13.0 40.0 23.6 35.7 17.0 4.7 31.0 56.6 18.9 1.2 9.5 13.0 17.2 10.1 3.8 19.8 21.0 3.0 27.3 20.9 48.9 9.0 12.8 17.7 8.0 61.1 16.7 12.5 32.5 52.5 42.4 69.3 36.5 8.5 19.5 37.8 35.1 4.6 9.9 23.8 37.2 34.7 92.6 75.9 28.4 31.2 6.7 10.6 1.5 5.6 6.8 6.5 12.5 3.6 9.4 9.2 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 215.7;SK-BR-3: 206.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB000109, HPA003001" Supported "Secreted to blood" 540000000 "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavourable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favourable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 151.9 148.7 21.4 32.8 27.0 83.7 67.7 18.6 47.4 56.3 59.3 41.4 41.9 61.6 25.9 48.2 46.2 34.2 90.0 86.0 25.3 27.6 150.5 163.5 102.6 81.1 49.6 25.7 41.2 62.3 21.3 24.9 56.1 42.8 33.9 33.7 234.4 64.1 42.3 76.2 50.8 90.9 23.3 36.7 87.6 47.0 29.8 29.7 21.1 36.3 42.9 41.4 64.6 43.5 4.9 22.7 51.1 83.8 28.4 26.1 58.7 15.6 42.4 4.9 20.4 62.1 21.2 7.9 11.6 36.2 15.6 18.5 10.5 215.7 3.8 30.1 29.9 84.4 7.1 13.0 4.3 16.1 15.4 5.8 8.0 13.2 65.5 13.3 61.6 34.2 57.0 8.4 15.5 11.4 6.9 23.2 27.6 57.7 3.4 7.5 11.6 17.0 4.9 6.0 14.1 55.0 49.0 6.8 6.7 13.8 206.2 39.1 80.7 18.4 14.3 47.5 7.3 6.5 18.6 32.0 40.1 2.4 69.2 36.1 39.8 29.0 83.8 25.2 26.1 47.6 15.1 4.9 12.2 18.3 22.7 3.2 14.3 18.3 51.1 28.4 38.5 19.2 13.5 58.7 21.4 27.0 18.6 47.4 25.3 27.6 49.6 25.7 42.8 29.7 CTSE ENSG00000196188 "Cathepsin E" P14091 1 206009264-206023909 "Enzymes, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 57.9;intestine: 47.3;stomach 1: 153.0" "Group enriched" "Detected in some" 7 "BEWO: 14.8;RT4: 28.1" "Group enriched" "Detected in many" 8 "lung cancer: 68.8;pancreatic cancer: 297.4;stomach cancer: 200.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012940, CAB032687" Enhanced "Intracellular and membrane" "CAB032687: AB_637901, HPA012940: " "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-2)" "unprognostic (2.72e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-3)" "unprognostic (1.45e-1)" "unprognostic (3.29e-2)" "unprognostic (2.87e-2)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "unprognostic (6.37e-3)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (2.61e-2)" "prognostic favourable (5.26e-5)" 0.2 0.1 0.1 3.7 0.1 3.0 0.1 0.1 0.1 0.1 47.3 0.3 0.8 29.3 0.1 0.7 0.6 0.5 57.9 0.3 0.1 0.1 0.2 0.2 24.9 0.0 0.1 0.0 0.1 2.2 0.0 0.5 0.0 0.1 1.3 3.2 0.0 0.1 0.0 0.1 0.1 29.7 0.0 0.1 0.2 153.0 0.1 0.0 0.3 4.2 0.0 1.1 1.8 0.4 0.2 0.7 0.0 0.4 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.5 0.6 0.0 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.7 2.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.9 0.5 0.0 0.2 0.0 0.5 0.6 28.1 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563463-66568841 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HSkMC: 28.2;SK-MEL-30: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cells: 7.5;T-cells: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431, HPA055610" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" 3600000 Cytosol "Vesicles, Plasma membrane" "CAB002141: AB_563471, HPA031431: , HPA055610: " "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-3)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.76e-2)" "unprognostic (3.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.69e-2)" "unprognostic (9.12e-2)" "prognostic favourable (8.92e-7)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (2.42e-1)" 28.1 29.4 24.7 8.0 29.0 1.8 31.1 38.4 47.1 37.3 23.8 32.6 25.2 5.8 38.1 29.8 12.9 34.3 37.3 34.5 25.3 20.5 29.8 45.4 17.3 8.5 28.0 26.0 68.2 23.1 42.6 15.9 20.2 25.4 32.3 8.1 35.0 35.5 37.8 35.8 19.7 9.4 34.6 22.4 10.4 17.8 37.1 30.1 0.8 18.6 14.2 6.3 22.2 21.5 2.1 1.1 0.5 0.7 7.5 9.7 2.4 0.1 9.2 5.0 12.9 21.3 8.6 3.6 6.5 16.5 6.8 4.8 0.0 8.2 0.0 11.0 14.2 0.9 8.5 2.8 3.6 2.2 0.0 0.3 3.8 0.0 11.9 0.1 5.0 28.2 9.6 1.5 1.1 4.3 2.8 1.5 8.5 1.9 0.1 1.1 0.6 3.4 0.0 1.9 1.6 6.1 0.2 6.0 6.4 17.4 2.0 52.3 13.2 0.8 2.8 2.7 2.7 3.2 0.6 8.8 0.1 0.0 6.5 0.1 4.1 0.0 0.7 0.4 6.5 0.7 7.0 2.0 5.6 7.3 0.8 2.1 9.7 5.5 0.5 7.5 0.3 1.1 1.7 2.4 24.7 29.0 38.4 47.1 25.3 20.5 28.0 26.0 25.4 30.1 CTSG CG ENSG00000100448 "Cathepsin G" P08311 14 24573522-24576260 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "bone marrow: 450.3" "Cell line enriched" "Detected in some" 7 "THP-1: 437.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.5;memory CD8 T-cell: 3.5;myeloid DC: 5.1;naive CD8 T-cell: 1.8;neutrophil: 7.1;NK-cell: 5.2;plasmacytoid DC: 5.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "CAB000110, HPA047737" Enhanced "Intracellular and membrane" 67000 "CAB000110: , HPA047737: " "unprognostic (1.67e-1)" "unprognostic (2.57e-2)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "prognostic favourable (1.57e-4)" "unprognostic (4.05e-2)" "unprognostic (4.13e-2)" "unprognostic (3.06e-1)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" "unprognostic (1.63e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "prognostic unfavourable (8.91e-4)" 15.1 0.5 0.0 6.0 0.0 450.3 6.0 0.0 0.6 10.0 5.1 0.0 2.8 1.1 6.2 19.7 6.4 0.8 16.7 23.4 0.0 0.0 2.1 2.0 9.2 3.7 0.0 0.0 1.5 3.4 0.8 0.5 3.0 0.0 8.2 3.2 2.6 6.3 6.9 1.1 19.5 8.9 14.9 0.0 10.7 3.2 2.8 0.0 15.6 0.5 12.0 5.1 2.9 3.3 0.0 5.7 7.1 6.5 5.2 3.5 12.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 437.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 64.9 0.0 0.0 6.5 0.0 1.1 1.0 0.0 0.0 1.0 3.5 5.1 0.0 0.0 1.8 7.1 5.2 0.0 5.7 0.0 12.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 82.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.5;HaCaT: 31.0;RT4: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 42.8" "Group enriched" "Detected in all" 5 "B-cells: 20.6;dendritic cells: 41.2;monocytes: 42.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" 10000000 "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favourable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 16.7 10.6 9.5 24.2 7.0 5.4 23.9 4.5 9.8 25.1 11.4 17.7 14.7 10.6 10.3 17.1 7.8 13.1 29.2 16.5 14.8 6.7 66.7 18.7 82.6 65.4 12.1 11.6 14.6 25.8 12.3 6.5 7.7 9.4 18.6 6.6 6.7 15.4 15.9 7.0 13.5 16.6 9.8 10.8 20.3 15.6 6.7 15.7 6.6 8.5 4.8 34.8 39.6 13.5 20.6 41.2 1.4 42.8 1.3 7.6 27.3 16.0 1.1 0.4 4.7 1.1 0.0 5.2 1.6 0.6 2.8 1.5 7.0 42.5 5.6 1.7 0.1 31.0 2.0 7.7 2.3 23.6 0.1 0.1 0.2 16.2 1.6 0.0 1.0 0.8 2.2 0.0 0.0 0.2 11.4 0.0 3.8 1.7 3.6 9.8 1.2 0.3 0.0 0.3 0.9 9.8 118.0 0.5 1.1 6.9 3.9 9.6 1.5 5.3 2.2 0.0 1.0 0.0 0.7 0.1 12.2 3.1 0.0 10.3 1.7 0.0 42.8 0.4 1.4 28.3 7.6 20.6 4.1 2.1 41.2 12.0 0.4 0.7 1.4 1.3 17.0 4.2 3.1 27.3 9.5 7.0 4.5 9.8 14.8 6.7 12.1 11.6 9.4 15.7 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150796208-150808323 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 104.1" "Group enriched" "Detected in some" 8 "ASC diff: 200.2;ASC TERT1: 73.3;BJ hTERT+: 161.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 6.7" "Lineage enriched" "Detected in many" 6 "monocytes: 6.7" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" Vesicles "HPA050346: " "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavourable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 104.1 2.4 1.2 6.5 1.6 1.3 79.3 2.4 2.3 70.6 23.6 2.2 10.1 2.7 72.5 25.9 26.5 12.5 53.4 14.7 1.1 1.1 3.4 1.8 8.7 10.4 1.1 1.7 25.4 2.9 0.3 3.0 30.6 2.6 24.2 11.5 56.0 10.9 6.8 19.9 44.0 11.0 26.9 2.0 5.6 8.6 24.1 0.9 1.1 7.1 13.2 10.7 38.0 48.2 0.1 1.0 1.0 6.7 0.5 1.2 1.8 0.1 0.1 0.3 0.3 200.2 73.3 0.2 5.7 161.8 0.4 0.8 0.0 0.1 0.1 0.2 11.1 0.2 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.0 1.0 0.1 0.4 14.6 0.5 4.5 0.1 0.6 0.0 0.5 0.4 0.3 0.0 0.7 1.1 0.1 0.0 0.1 0.0 0.4 0.1 0.1 0.6 0.3 0.0 3.0 0.2 0.2 0.4 0.2 0.1 0.2 0.2 0.6 0.5 1.1 17.0 0.0 0.9 0.0 6.7 1.0 0.7 3.4 0.2 0.0 0.6 0.2 0.4 0.1 0.3 0.5 0.6 0.5 2.0 1.0 1.2 1.8 1.2 1.6 2.4 2.3 1.1 1.1 1.1 1.7 2.6 0.9 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87725519-87731393 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 237.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 198.5;HSkMC: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "intermediate monocyte: 31.0;non-classical monocyte: 44.3" "Lineage enriched" "Detected in many" 10 "monocytes: 44.3" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" 17000000 "Golgi apparatus" Vesicles "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavourable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavourable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favourable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 60.3 21.5 10.4 27.2 24.6 18.4 23.3 6.9 12.3 14.8 23.2 14.1 13.7 9.0 24.1 22.3 11.4 25.7 20.7 37.7 10.7 11.4 65.4 98.0 53.1 80.5 18.9 7.7 25.0 14.3 18.8 18.0 237.0 18.4 19.4 13.0 23.2 22.0 23.5 29.3 9.1 12.0 36.6 16.1 108.1 17.5 14.1 15.7 6.8 19.2 9.4 10.1 41.3 26.5 0.0 1.7 0.1 44.3 0.0 4.3 2.4 6.3 36.8 2.5 4.3 46.3 198.5 15.4 20.5 59.7 17.6 22.1 3.5 5.9 0.0 9.6 26.5 5.4 3.3 6.6 14.5 0.1 3.2 1.1 10.4 8.6 30.0 0.0 4.4 91.8 11.2 28.8 11.2 13.8 11.9 0.0 25.3 10.6 0.0 0.7 4.9 7.0 1.5 1.5 0.0 12.3 3.3 3.7 4.5 4.3 9.6 23.5 1.1 7.3 21.7 15.8 8.6 57.5 8.6 1.6 5.9 0.0 57.8 0.0 5.2 0.1 3.5 0.1 0.0 31.0 0.0 0.0 1.8 0.0 1.7 0.0 4.3 0.3 0.1 0.0 44.3 0.1 0.3 2.4 10.4 24.6 6.9 11.7 10.7 11.4 18.9 7.7 18.4 15.7 CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155924118-155953917 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 12.3;HSkMC: 14.6;Karpas-707: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" 24000 "HPA002041: AB_1078408" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (9.10e-3)" "unprognostic (2.55e-1)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (4.87e-3)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" 13.7 16.4 11.9 12.6 12.0 1.8 14.9 3.7 12.4 16.0 18.5 11.6 10.2 13.3 19.3 27.3 10.8 15.6 16.9 19.7 9.7 8.6 21.2 41.6 26.4 19.4 10.2 6.7 16.3 10.7 13.6 9.4 18.7 9.7 16.1 9.8 24.0 13.8 16.8 5.9 6.2 27.5 14.4 11.4 19.3 10.8 9.0 7.7 5.5 17.1 10.2 10.3 12.4 12.5 7.0 8.9 5.3 14.8 12.0 10.9 8.9 0.3 0.2 1.5 1.6 5.6 12.3 0.0 3.5 7.1 1.3 1.8 0.0 4.6 0.0 0.7 2.3 0.0 0.0 0.3 0.9 5.2 0.1 0.4 0.0 0.0 5.9 0.7 0.1 14.6 1.3 0.8 0.6 1.2 0.0 27.5 4.1 0.3 0.3 0.1 0.3 0.2 1.6 0.3 1.7 5.3 2.3 0.2 1.7 0.8 2.9 1.0 1.5 1.0 2.0 4.3 0.2 0.4 1.1 3.1 0.0 0.0 7.8 0.0 5.8 5.3 12.0 0.8 7.9 14.8 10.9 5.8 6.1 7.3 8.9 7.0 6.7 6.8 0.5 12.0 10.7 8.3 6.8 8.9 11.9 12.0 3.7 12.4 9.7 8.6 10.2 6.7 9.7 7.7 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730196-150765957 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 171.4;lymphoid tissue: 111.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 21.1;HMC-1: 50.3;U-698: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 171.4;intermediate monocyte: 151.2;myeloid DC: 43.5;neutrophil: 94.5;non-classical monocyte: 138.5" "Group enriched" "Detected in all" 9 "dendritic cells: 43.5;granulocytes: 94.5;monocytes: 171.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" 19000000 Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 41.6 9.3 6.8 32.3 10.3 30.3 9.7 1.9 6.2 4.7 32.9 6.6 5.6 19.6 3.7 12.9 8.8 10.7 15.9 17.3 6.4 5.1 9.6 21.5 55.8 99.5 12.6 2.3 7.6 6.4 0.4 3.4 14.4 9.3 7.5 33.4 6.5 12.9 3.3 3.5 3.8 38.0 6.8 17.1 111.4 13.8 3.8 9.5 12.9 7.6 4.6 22.8 21.5 5.3 11.1 43.5 94.5 171.4 3.3 5.6 145.4 1.0 3.2 0.0 0.0 0.4 0.3 0.3 0.0 3.2 0.2 0.6 0.0 21.1 14.5 1.6 0.1 0.4 0.0 0.1 0.0 8.1 0.0 6.4 0.1 0.0 0.0 8.7 50.3 0.6 0.0 1.8 0.1 1.2 0.6 12.7 0.4 0.0 0.0 6.2 0.0 0.0 3.6 1.2 17.8 3.9 3.1 0.0 0.1 0.2 0.9 0.3 0.0 17.8 1.7 1.3 0.2 0.0 0.2 8.8 0.8 106.9 7.4 9.4 0.8 1.2 171.4 16.5 3.2 151.2 3.9 11.1 3.9 3.8 43.5 10.2 3.9 3.6 94.5 3.3 138.5 9.4 5.6 145.4 6.8 10.3 1.9 6.2 6.4 5.1 12.6 2.3 9.3 9.5 CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029679-97039643 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 154.7" "Cell line enriched" "Detected in many" 8 "BEWO: 113.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "NK-cell: 4.2;plasmacytoid DC: 15.7" "Group enriched" "Detected in many" 42 "dendritic cells: 15.7;NK-cells: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" 260000 "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favourable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavourable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavourable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavourable (2.39e-4)" 0.7 0.0 0.4 0.6 0.7 0.0 3.5 0.4 1.0 23.0 1.4 2.0 0.4 0.5 1.5 1.5 9.8 0.6 0.5 0.2 0.8 0.6 9.7 0.4 0.6 0.2 1.5 0.7 0.4 1.1 1.1 0.9 8.7 1.6 0.5 1.6 4.3 5.0 0.6 0.5 25.0 0.6 0.2 3.0 0.2 1.1 32.4 1.0 154.7 0.7 6.3 2.7 0.2 9.9 0.2 15.7 0.2 0.0 4.2 0.0 0.1 7.3 2.2 2.5 6.5 0.1 0.0 113.4 0.0 0.0 1.6 1.3 14.9 7.3 0.1 0.6 0.1 14.0 12.1 8.9 2.3 0.0 1.6 0.3 0.7 2.3 0.0 0.0 1.0 0.0 3.0 0.4 0.3 0.5 0.2 0.0 2.9 2.7 0.2 0.1 15.0 2.1 0.0 5.4 0.1 2.2 0.9 0.6 1.1 7.4 2.6 2.6 4.6 0.8 0.0 0.4 7.4 0.1 0.8 1.5 4.0 0.1 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.2 4.2 0.0 15.7 0.0 0.1 0.4 0.7 0.4 1.0 0.8 0.6 1.5 0.7 1.6 1.0 CTSW ENSG00000172543 "Cathepsin W" P56202 11 65879809-65883741 "Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 157.2;bone marrow: 41.4" "Group enriched" "Detected in some" 23 "HEL: 37.9;NB-4: 86.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "gdT-cell: 106.6;MAIT T-cell: 67.7;memory CD8 T-cell: 68.3;naive CD8 T-cell: 51.4;NK-cell: 157.2" "Group enriched" "Detected in many" 48 "NK-cells: 157.2;T-cells: 106.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB016345 Enhanced "Secreted to blood" 340000 "CAB016345: AB_626813" "prognostic favourable (3.06e-4)" "unprognostic (2.06e-2)" "unprognostic (2.71e-2)" "prognostic favourable (8.36e-6)" "unprognostic (1.21e-1)" "prognostic favourable (9.89e-4)" "unprognostic (5.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (5.14e-3)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "prognostic unfavourable (8.84e-6)" "unprognostic (3.86e-2)" "unprognostic (3.78e-1)" "unprognostic (1.26e-1)" "unprognostic (4.01e-3)" 5.2 1.2 0.9 4.9 1.0 41.4 2.3 0.6 0.7 3.9 4.9 0.8 0.5 2.4 8.4 4.0 2.1 2.1 2.5 9.0 0.9 1.0 2.5 6.8 12.7 36.0 1.1 0.6 3.0 1.1 0.0 1.4 10.7 1.4 7.4 2.5 6.3 10.9 1.5 1.9 1.5 5.9 1.7 2.1 33.1 3.3 3.4 0.4 11.1 3.1 1.3 18.2 4.5 2.6 0.4 2.7 2.3 0.3 157.2 106.6 45.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 37.9 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.4 86.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 2.3 0.0 2.3 0.2 0.3 106.6 0.2 67.7 0.4 11.7 68.3 2.7 0.3 7.0 51.4 2.0 157.2 0.3 1.7 1.6 45.7 0.9 1.0 0.6 0.7 0.9 1.0 1.1 0.6 1.4 0.4 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58995185-59007247 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.2;intermediate monocyte: 2.7;memory B-cell: 1.0;myeloid DC: 3.9;naive B-cell: 1.9;neutrophil: 3.5;non-classical monocyte: 2.9;plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" 85000000 Vesicles "CAB025114: , HPA049876: , HPA053504: " "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavourable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 70.7 27.9 12.4 40.8 20.4 20.7 51.2 14.6 13.5 25.4 52.8 16.0 19.9 40.8 20.6 25.5 20.1 20.7 22.3 50.1 9.8 13.3 34.9 83.7 54.3 61.2 18.8 10.5 29.7 29.0 30.6 27.6 38.6 19.2 28.8 37.8 31.5 40.3 17.7 20.7 12.9 63.6 26.4 22.1 56.5 19.2 13.8 14.9 18.4 42.4 17.5 35.8 29.8 21.5 1.9 3.9 3.5 3.2 0.3 0.6 0.8 27.2 21.2 0.0 0.0 25.0 28.8 15.0 44.9 49.7 34.4 30.8 41.0 45.9 15.0 29.7 118.0 21.8 13.5 42.5 23.6 47.9 1.8 13.7 34.4 0.0 26.2 1.6 47.7 24.5 25.7 15.0 18.0 54.4 9.9 7.6 23.0 0.0 0.1 14.8 1.7 21.2 0.3 0.1 18.0 25.1 6.4 0.4 0.3 34.9 40.4 0.1 18.7 23.2 59.8 0.0 23.2 30.2 0.2 36.2 22.0 2.8 0.4 33.1 0.0 0.0 3.2 0.3 0.6 2.7 0.0 1.0 0.4 0.1 3.9 1.9 0.4 0.1 3.5 0.3 2.9 2.2 0.2 0.8 12.4 20.4 14.6 13.5 9.8 13.3 18.8 10.5 19.2 14.9 CWC27 "NY-CO-10, SDCCAG-10, SDCCAG10" ENSG00000153015 "CWC27 spliceosome associated protein homolog" Q6UX04 5 64768930-65018763 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Disease mutation, Dwarfism, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020344, HPA024149, HPA065809" Approved Enhanced Nucleoplasm Nucleoplasm "HPA020344: AB_1856644, HPA024149: AB_1856645, HPA065809: " "unprognostic (1.71e-1)" "unprognostic (6.47e-3)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (8.91e-2)" "unprognostic (4.00e-3)" "prognostic unfavourable (5.27e-6)" "unprognostic (1.58e-2)" "unprognostic (3.43e-2)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.46e-1)" "unprognostic (2.05e-1)" "unprognostic (2.74e-1)" "unprognostic (7.45e-3)" 15.6 16.4 22.0 14.9 30.4 21.7 16.4 30.1 25.6 16.5 17.5 13.8 14.0 11.8 19.4 15.7 17.3 14.9 13.8 22.1 20.6 19.9 17.5 12.1 12.8 17.0 22.3 20.7 23.3 10.9 21.4 28.8 17.5 26.2 18.6 18.7 11.4 13.3 16.0 24.0 13.8 15.9 24.7 23.3 15.0 13.9 19.6 23.6 22.5 17.2 18.2 18.6 18.6 20.0 15.1 14.6 8.6 11.5 17.0 15.9 9.0 15.2 10.2 18.3 33.9 15.7 19.2 20.5 16.0 13.4 18.0 18.9 17.0 19.4 22.6 28.1 16.6 9.7 19.2 29.0 32.8 18.8 15.7 17.0 17.2 14.1 24.1 17.7 11.5 12.8 22.3 22.6 28.8 19.0 16.5 14.9 17.8 15.1 24.6 16.1 14.8 12.3 22.9 24.7 23.5 17.1 13.3 21.8 9.6 19.5 8.0 18.1 17.4 26.1 15.7 10.6 18.7 16.9 25.5 11.7 15.1 22.2 19.8 31.2 18.7 8.6 11.5 7.9 12.8 11.3 15.5 15.1 14.2 15.9 14.6 11.9 15.4 15.9 2.5 17.0 8.5 12.0 15.1 9.0 22.0 30.4 30.1 25.6 20.6 19.9 22.3 20.7 26.2 23.6 CYB5R1 "humb5R2, NQO3A2" ENSG00000159348 "Cytochrome b5 reductase 1" Q9UHQ9 1 202961869-202967280 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 119.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010641, HPA014147" Enhanced Uncertain Nucleoli,Mitochondria,Cytosol 860000 "Nucleoli, Mitochondria, Cytosol" "HPA010641: AB_1078600, HPA014147: AB_1847370" "unprognostic (6.36e-2)" "unprognostic (8.51e-2)" "unprognostic (1.16e-2)" "prognostic favourable (1.14e-4)" "unprognostic (1.86e-2)" "unprognostic (4.34e-2)" "unprognostic (8.46e-2)" "unprognostic (1.28e-1)" "unprognostic (4.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.73e-2)" "unprognostic (2.33e-1)" "unprognostic (6.14e-2)" "unprognostic (2.37e-3)" "unprognostic (1.69e-1)" 9.6 14.5 7.8 5.0 8.4 3.9 16.9 6.2 11.0 11.6 7.5 8.7 10.6 4.4 10.1 32.3 13.7 16.4 9.2 33.9 7.3 9.2 15.5 18.4 10.1 11.7 10.0 9.1 10.8 11.1 16.3 11.1 63.8 11.9 10.5 5.0 15.7 14.4 10.1 119.2 28.5 6.9 10.6 7.4 10.8 18.6 20.1 6.7 11.7 13.5 26.4 10.0 13.6 10.1 20.2 21.9 25.7 33.3 17.2 26.5 28.8 8.3 5.2 4.6 9.4 42.9 9.9 45.1 16.8 15.8 10.9 9.8 4.3 9.9 5.2 14.3 16.7 46.3 3.7 14.4 7.2 7.5 9.5 2.9 6.3 4.9 15.5 2.5 7.4 15.8 47.6 12.0 6.6 7.2 8.8 9.4 39.4 9.8 3.2 2.2 3.0 10.0 5.3 22.2 11.1 10.3 10.0 3.9 4.8 9.4 31.4 13.6 14.5 5.7 7.0 12.5 5.3 4.7 9.3 8.8 10.4 2.4 13.8 3.9 9.3 11.6 33.3 25.6 16.7 24.2 22.2 13.6 19.3 17.8 21.9 20.2 26.5 18.8 25.7 17.2 15.7 15.1 19.1 28.8 7.8 8.4 6.2 11.0 7.3 9.2 10.0 9.1 11.9 6.7 CYB5R2 ENSG00000166394 "Cytochrome b5 reductase 2" Q6BCY4 11 7665100-7677222 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 58.8" "Cell line enhanced" "Detected in many" "BJ hTERT+: 41.6;BJ hTERT+ SV40 Large T+: 22.3;BJ hTERT+ SV40 Large T+ RasG12V: 20.2;HBF TERT88: 17.8;NTERA-2: 23.4;WM-115: 32.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 5.9;memory B-cell: 12.2" "Group enriched" "Detected in many" 9 "B-cells: 12.2;granulocytes: 5.9" "Low region specificity" "Detected in many" "HPA038962, HPA061707" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Golgi apparatus" Nucleoplasm "HPA038962: AB_10675954, HPA061707: " "unprognostic (1.47e-1)" "unprognostic (2.56e-2)" "unprognostic (8.90e-3)" "unprognostic (4.41e-2)" "unprognostic (4.13e-3)" "unprognostic (1.60e-2)" "unprognostic (4.02e-2)" "unprognostic (2.48e-1)" "unprognostic (3.41e-2)" "unprognostic (1.30e-2)" "unprognostic (2.64e-3)" "unprognostic (1.10e-1)" "unprognostic (4.78e-2)" "unprognostic (1.40e-1)" "unprognostic (8.16e-2)" "unprognostic (1.70e-1)" "unprognostic (7.01e-2)" 3.3 1.9 9.3 2.8 12.1 1.9 7.7 3.1 12.3 6.6 2.3 26.1 4.2 1.3 10.0 13.1 8.0 5.2 3.4 2.0 11.2 5.3 2.4 2.5 4.6 3.8 22.3 7.3 14.9 2.2 23.1 0.6 6.7 11.6 7.8 2.7 12.2 12.8 11.6 0.8 23.4 1.7 6.8 12.4 2.0 2.2 58.8 14.5 0.2 2.6 6.7 4.9 5.9 7.1 12.2 0.0 5.9 1.0 0.0 0.2 0.7 2.2 1.1 0.5 0.0 0.1 0.6 7.7 14.5 41.6 22.3 20.2 0.2 3.1 0.0 3.5 7.4 0.2 0.0 0.1 17.8 0.0 0.0 0.0 1.2 0.3 12.1 0.1 2.2 6.1 0.4 0.0 1.2 1.8 2.2 0.0 0.1 0.0 0.0 0.0 23.4 1.1 11.0 0.0 0.0 0.0 1.5 0.0 0.2 0.1 9.3 0.6 1.6 3.0 0.0 2.1 0.0 0.1 1.1 0.0 0.0 3.4 0.1 0.0 32.0 0.0 1.0 5.9 0.0 0.5 0.0 12.2 0.2 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.7 9.3 12.1 3.1 12.3 11.2 5.3 22.3 7.3 11.6 14.5 CYB5R3 DIA1 ENSG00000100243 "Cytochrome b5 reductase 3" P00387 22 42617840-42649568 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 115.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001566 Approved Supported "Endoplasmic reticulum" 67000000 "Endoplasmic reticulum" "HPA001566: AB_1078601" "unprognostic (4.73e-2)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-1)" "unprognostic (1.04e-2)" "prognostic unfavourable (2.13e-5)" "unprognostic (2.45e-1)" "unprognostic (8.22e-3)" "unprognostic (3.01e-1)" "unprognostic (2.72e-2)" "unprognostic (6.76e-2)" "unprognostic (3.33e-3)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-1)" "unprognostic (5.24e-2)" 79.7 57.1 33.2 22.8 32.6 19.3 86.8 19.5 33.1 52.4 31.9 37.6 51.8 25.9 51.9 35.0 39.1 39.3 38.6 86.4 31.3 24.1 43.3 78.2 43.5 30.3 31.8 25.4 58.8 21.9 15.1 27.2 32.1 33.9 40.6 21.3 37.9 29.3 96.4 34.4 43.1 32.5 55.5 36.3 20.2 33.7 44.0 25.9 14.1 30.1 28.4 23.2 43.4 53.5 28.6 37.6 70.3 39.7 14.2 22.3 19.7 16.2 10.4 17.2 10.5 115.5 91.8 10.1 47.8 44.4 35.7 31.9 13.6 12.8 7.7 21.4 88.4 15.0 11.4 23.7 18.4 8.3 25.6 10.9 18.0 26.2 29.4 15.2 20.4 55.3 18.8 25.7 17.1 29.5 9.4 40.0 48.5 17.9 14.9 14.0 6.8 19.2 11.0 20.9 17.0 27.5 11.9 7.6 9.9 15.8 15.3 17.4 12.2 14.7 45.2 38.8 24.2 26.1 18.0 10.6 11.5 9.4 45.2 8.9 31.9 26.3 25.7 70.3 19.7 32.4 19.9 28.6 19.1 21.6 37.6 26.4 13.6 14.3 13.4 14.2 39.7 34.3 22.3 19.7 33.2 32.6 19.5 33.1 31.3 24.1 31.8 25.4 33.9 25.9 CYB5R4 "b5+b5R, dJ676J13.1, NCB5OR" ENSG00000065615 "Cytochrome b5 reductase 4" Q7L1T6 6 83859643-83967424 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 49.6" "Cell line enhanced" "Detected in all" "HDLM-2: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 49.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018992 Approved "HPA018992: AB_1847371" "unprognostic (4.86e-3)" "unprognostic (1.16e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-2)" "unprognostic (1.72e-1)" "unprognostic (3.25e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (4.77e-1)" "unprognostic (6.77e-2)" "unprognostic (1.39e-2)" "unprognostic (5.44e-1)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.15e-1)" "unprognostic (8.15e-2)" 9.3 8.2 4.5 17.9 9.1 23.1 9.6 11.5 8.4 6.3 10.5 8.0 6.2 10.0 7.2 7.6 11.1 6.1 5.3 10.8 4.9 5.0 8.7 8.6 12.3 23.4 10.2 3.4 6.0 8.5 3.6 10.5 12.6 7.3 6.5 8.2 4.3 9.3 4.3 11.9 6.6 11.0 8.8 12.2 18.8 10.8 21.6 9.7 14.2 5.6 6.6 11.9 10.9 7.6 6.9 11.4 49.6 14.6 3.3 5.6 6.3 5.0 4.4 3.2 4.1 1.8 2.3 5.9 3.4 5.1 5.2 7.5 5.7 3.4 9.3 5.4 2.1 4.3 2.9 4.8 3.9 35.8 6.5 22.5 2.6 3.2 3.3 13.4 20.2 2.9 1.3 3.5 3.6 2.6 8.0 7.2 3.6 1.9 3.5 3.7 1.8 4.2 5.9 11.7 3.3 2.3 5.3 8.4 4.6 4.2 4.1 4.7 2.4 8.0 3.4 5.2 4.3 10.7 10.9 8.2 12.6 5.2 6.0 9.3 5.8 20.8 14.6 42.2 4.4 12.1 3.5 6.9 3.8 3.9 11.4 6.6 2.5 3.9 49.6 3.3 13.1 4.8 5.6 6.3 4.5 9.1 11.5 8.4 4.9 5.0 10.2 3.4 7.3 9.7 CYB5RL LOC606495 ENSG00000215883 "Cytochrome b5 reductase like" Q6IPT4 1 54169651-54200036 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA042671, HPA060463" Approved Enhanced Nucleoplasm Nucleoplasm "HPA042671: , HPA060463: " "unprognostic (2.03e-1)" "unprognostic (1.36e-1)" "unprognostic (1.72e-2)" "unprognostic (1.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-3)" "unprognostic (1.90e-4)" "unprognostic (6.45e-3)" "unprognostic (9.75e-2)" "unprognostic (2.04e-1)" "unprognostic (5.93e-2)" "unprognostic (2.58e-1)" "unprognostic (2.35e-1)" "unprognostic (1.80e-2)" "unprognostic (5.08e-2)" "unprognostic (5.74e-2)" "unprognostic (2.86e-1)" 1.7 4.9 1.9 0.8 1.9 1.6 2.4 1.3 1.7 2.5 2.2 2.6 2.5 2.3 2.1 2.9 2.0 3.5 2.1 1.7 2.7 2.6 1.5 2.1 2.3 5.0 4.1 1.8 4.2 1.1 2.1 2.7 3.2 1.4 3.7 3.9 1.5 2.4 1.8 2.5 2.8 1.2 3.1 2.2 2.8 1.8 1.4 1.8 2.6 3.5 3.1 1.5 1.2 4.0 5.4 7.4 7.7 6.1 5.8 2.5 3.2 4.6 6.3 6.8 5.1 4.4 6.7 3.8 2.2 3.7 11.5 3.3 7.1 7.6 4.7 7.6 8.7 5.2 4.6 6.5 3.9 3.1 4.5 7.4 3.4 5.4 8.2 3.2 4.5 5.0 6.5 3.6 7.4 4.3 10.5 9.1 6.2 2.8 4.6 11.0 5.4 2.1 7.3 6.5 5.1 5.0 2.4 4.8 3.9 7.0 5.7 4.8 7.7 9.9 5.4 13.9 7.2 2.2 1.8 1.6 1.0 3.5 0.8 1.1 1.5 0.6 1.6 1.4 1.2 1.2 2.6 3.1 0.8 1.8 0.5 1.2 CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095" Approved Supported "Nucleoplasm,Centriolar satellite" "Centriolar satellite" Nucleoplasm "CAB011713: AB_731794, HPA050095: " "unprognostic (9.83e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "unprognostic (2.83e-2)" "unprognostic (3.84e-1)" "unprognostic (5.06e-2)" "unprognostic (3.87e-2)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (6.83e-2)" "unprognostic (8.42e-2)" 9.3 16.2 13.9 22.9 26.4 51.1 9.1 14.2 20.9 9.2 10.3 18.8 12.8 10.2 16.1 8.1 15.3 8.5 13.3 12.7 15.7 17.0 9.4 13.2 15.6 30.7 16.3 14.3 11.5 12.2 20.3 27.8 9.8 20.0 11.0 12.7 13.3 12.6 10.9 31.7 12.4 14.2 12.5 16.3 23.4 12.4 22.6 13.7 16.9 16.2 8.0 29.3 14.1 12.6 9.2 10.2 31.4 9.8 13.6 19.1 10.2 9.1 2.9 3.3 3.7 5.3 7.7 3.0 13.6 19.9 14.2 8.4 2.4 4.3 10.6 4.9 13.2 3.6 3.9 8.2 21.1 46.4 6.0 5.3 5.1 1.9 10.6 5.2 24.9 8.4 6.7 17.1 17.9 5.7 2.2 9.2 19.8 1.3 5.1 7.6 3.5 4.8 4.6 6.8 10.1 4.6 3.2 4.3 3.3 11.5 3.9 3.3 3.9 6.6 6.4 24.3 5.5 8.5 5.5 24.3 23.1 11.8 17.8 5.9 5.1 31.4 8.6 20.8 10.7 9.8 12.9 9.2 15.8 14.4 10.2 6.2 14.7 11.4 19.4 13.6 9.5 6.2 19.1 10.2 13.9 26.4 14.2 20.9 15.7 17.0 16.3 14.3 20.0 13.7 CYP11A1 "CYP11A, P450SCC" ENSG00000140459 "Cytochrome P450 family 11 subfamily A member 1" P05108 15 74337759-74367740 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Steroidogenesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 145.3;placenta: 157.2" "Group enriched" "Detected in some" 4 "BEWO: 43.1;HEL: 34.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 36 "basal ganglia: 14.8" "Cell type enriched" "Detected in single" 37 "basophil: 15.8" "Lineage enriched" "Detected in single" 37 "granulocytes: 15.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 6.9" HPA016436 Enhanced "HPA016436: AB_1847423" "unprognostic (8.89e-2)" "unprognostic (6.96e-2)" "unprognostic (4.95e-3)" "unprognostic (9.31e-2)" "unprognostic (9.42e-4)" "unprognostic (1.90e-1)" "unprognostic (1.55e-3)" "unprognostic (8.06e-2)" "unprognostic (3.04e-1)" "unprognostic (2.95e-1)" "unprognostic (1.77e-2)" "unprognostic (5.45e-2)" "unprognostic (9.66e-4)" "unprognostic (2.40e-2)" "unprognostic (2.74e-1)" "unprognostic (3.04e-2)" "unprognostic (7.95e-2)" 0.4 145.3 0.4 0.1 14.8 0.0 0.4 0.3 0.3 0.2 0.2 7.6 0.1 0.0 0.3 0.5 1.5 0.3 0.0 0.3 0.3 0.2 0.1 0.7 0.1 0.0 0.3 0.2 9.2 0.1 0.0 0.4 157.2 0.2 0.2 0.0 0.3 0.1 0.6 0.3 0.1 0.1 0.3 0.3 5.7 0.1 20.4 0.1 0.0 0.1 0.3 0.7 0.2 0.2 0.0 0.0 15.8 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 43.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 34.2 1.0 0.3 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 15.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.4 14.8 0.3 0.3 0.3 0.2 0.3 0.2 0.2 0.1 CYP11B1 "CPN1, CYP11B, FHI, P450C11" ENSG00000160882 "Cytochrome P450 family 11 subfamily B member 1" P15538 8 142872356-142879846 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 781 "adrenal gland: 224.9" "Group enriched" "Detected in some" 8 "SCLC-21H: 3.0;SH-SY5Y: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA056348, HPA057752" Supported "HPA049171: , HPA056348: , HPA057752: " 0.0 224.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP11B2 "ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo" ENSG00000179142 "Cytochrome P450 family 11 subfamily B member 2" P19099 8 142910559-142917843 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 259 "adrenal gland: 51.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA056348, HPA057752" Supported "HPA049171: , HPA056348: , HPA057752: " 0.0 51.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP17A1 "CPT7, CYP17, P450C17, S17AH" ENSG00000148795 "Cytochrome P450 family 17 subfamily A member 1" P05093 10 102830531-102837533 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Steroidogenesis "Lyase, Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "adrenal gland: 425.4" "Group enriched" "Detected in some" 4 "HMC-1: 7.8;SCLC-21H: 3.1" "Cancer enriched" "Detected in many" 5 "liver cancer: 22.7" "Region enriched" "Detected in single" 103 "basal ganglia: 19.7" "Cell type enhanced" "Detected in single" "neutrophil: 1.2" "Lineage enhanced" "Detected in single" "granulocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA048533 Enhanced "Intracellular and membrane" "HPA048533: " "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (3.01e-2)" "unprognostic (9.08e-2)" "unprognostic (1.91e-1)" "unprognostic (6.29e-2)" "unprognostic (2.92e-3)" "unprognostic (2.39e-4)" "unprognostic (8.26e-2)" "unprognostic (2.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.13e-1)" "prognostic favourable (5.43e-7)" "unprognostic (1.07e-1)" "unprognostic (5.56e-2)" "unprognostic (1.66e-2)" "unprognostic (2.94e-4)" 0.0 425.4 0.0 0.1 19.7 0.0 0.0 0.1 0.1 0.1 0.0 78.5 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.0 0.0 6.4 1.7 0.1 0.0 0.0 0.0 3.2 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 82.3 0.0 0.1 2.2 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 7.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 19.7 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338610 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "placenta: 440.1" "Cell line enhanced" "Detected in some" "ASC TERT1: 44.8;HDLM-2: 7.8;HSkMC: 15.0" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in single" 8 "basal ganglia: 5.9" "Cell type enriched" "Detected in single" 17 "neutrophil: 1.7" "Lineage enriched" "Detected in single" 17 "granulocytes: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000355, HPA051194" Enhanced Approved Mitochondria Mitochondria "CAB000355: , HPA051194: " "unprognostic (9.41e-2)" "unprognostic (7.44e-2)" "unprognostic (9.52e-5)" "unprognostic (6.81e-2)" "unprognostic (2.72e-1)" "unprognostic (4.25e-4)" "unprognostic (5.18e-5)" "unprognostic (1.54e-3)" "unprognostic (2.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.97e-1)" "unprognostic (5.37e-2)" "unprognostic (1.54e-5)" "unprognostic (2.52e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.11e-1)" 9.0 4.6 0.2 0.2 5.9 0.1 2.1 0.2 0.3 0.9 0.3 0.3 0.2 0.4 0.2 0.3 0.3 0.2 0.3 1.3 0.2 0.7 0.3 0.2 0.6 0.2 0.2 0.2 4.4 0.6 0.1 0.2 440.1 0.2 0.5 0.1 0.2 0.9 1.4 0.8 2.3 0.2 0.7 0.5 0.5 0.1 3.0 0.2 0.3 3.0 0.2 0.2 1.2 0.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 44.8 2.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 7.8 0.0 0.3 0.1 3.7 0.2 0.0 0.0 15.0 0.0 0.1 1.8 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 1.4 0.6 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.2 5.9 0.2 0.3 0.2 0.7 0.2 0.2 0.2 0.2 CYP1A1 "CP11, CYP1, P1-450, P450-C, P450DX" ENSG00000140465 "Cytochrome P450 family 1 subfamily A member 1" P04798 15 74719542-74725610 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "liver: 38.3;lung: 144.1;urinary bladder: 40.0" "Cell line enhanced" "Detected in some" "CACO-2: 24.0;hTCEpi: 13.1;HUVEC TERT2: 12.6;SK-BR-3: 9.8" "Group enriched" "Detected in some" 24 "liver cancer: 18.6;urothelial cancer: 54.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB018654 Uncertain "CAB018654: AB_2088699" "unprognostic (1.71e-2)" "unprognostic (7.86e-2)" "unprognostic (2.57e-2)" "unprognostic (2.89e-1)" "unprognostic (5.45e-3)" "unprognostic (6.34e-2)" "unprognostic (3.08e-1)" "unprognostic (6.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (4.21e-2)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-1)" "unprognostic (1.28e-1)" 9.3 0.4 0.1 0.4 0.2 0.2 7.7 0.2 0.5 2.3 0.7 0.4 3.9 0.5 3.8 4.4 1.2 0.2 11.3 3.0 0.1 0.0 0.7 38.3 144.1 0.2 0.1 0.1 0.5 0.5 0.2 0.1 3.5 0.3 0.2 0.2 0.8 2.1 0.5 1.5 8.1 10.7 5.9 0.2 0.2 0.4 0.3 0.1 0.1 0.8 0.8 8.0 40.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.4 0.1 0.0 0.3 0.0 7.8 0.0 0.1 0.4 0.2 24.0 1.0 0.2 6.5 0.0 7.5 0.5 4.8 0.2 0.0 0.7 0.3 1.7 3.5 0.1 0.2 7.7 0.0 13.1 0.2 1.0 12.6 1.4 0.2 0.0 0.5 0.0 0.2 0.1 1.9 0.7 0.0 0.3 0.0 1.6 0.4 0.2 1.1 9.8 2.5 0.3 0.1 0.6 1.1 0.3 3.5 0.0 0.5 0.1 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.2 0.3 0.1 0.0 0.1 0.1 0.3 0.1 CYP1A2 "CP12, P3-450" ENSG00000140505 "Cytochrome P450 family 1 subfamily A member 2" P05177 15 74748844-74756202 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "liver: 143.0" "Cell line enhanced" "Detected in many" "SK-BR-3: 6.0" "Group enriched" "Detected in some" 22 "liver cancer: 25.3;urothelial cancer: 6.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB016531 Enhanced "CAB016531: AB_629359" "unprognostic (1.54e-4)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-2)" "unprognostic (5.48e-2)" "unprognostic (2.33e-2)" "unprognostic (7.41e-2)" "unprognostic (2.53e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.7 1.1 4.5 1.2 1.1 0.7 0.3 1.1 1.0 2.7 2.2 0.2 0.0 1.6 0.7 0.0 0.0 0.2 0.6 1.3 2.2 0.5 0.0 1.2 0.1 0.2 0.1 0.6 1.2 2.8 1.6 0.8 0.1 1.9 1.1 0.4 0.3 0.1 0.0 0.2 1.9 4.1 0.0 0.8 2.5 1.3 1.7 0.6 2.6 2.4 0.9 0.0 2.3 2.2 1.1 2.1 6.0 0.4 1.6 1.0 0.4 1.1 1.4 1.1 1.2 1.0 0.7 1.6 1.1 2.4 1.2 3.2 1.2 1.2 0.6 0.6 0.5 0.8 0.7 0.5 0.4 1.7 0.7 0.7 4.5 1.1 0.8 1.1 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease mutation, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 45.0;lung: 39.2" "Cell line enhanced" "Detected in many" "ASC diff: 24.2;ASC TERT1: 25.9;HSkMC: 103.9;SiHa: 48.4;U-87 MG: 26.4" "Low cancer specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "classical monocyte: 45.0" "Lineage enriched" "Detected in many" 22 "monocytes: 45.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB011705, HPA026863" Approved Uncertain Mitochondria Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavourable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavourable (2.76e-4)" 9.1 3.1 0.5 9.4 1.2 0.0 11.4 1.0 1.2 11.4 2.1 0.7 4.5 0.0 12.8 5.9 3.5 15.0 6.9 17.5 1.2 8.8 3.5 39.2 26.3 3.1 1.0 6.1 3.6 0.0 1.3 0.8 3.3 10.7 0.0 19.3 0.0 13.0 4.8 0.5 1.4 10.6 5.1 15.7 0.3 3.9 0.5 5.1 2.5 1.1 4.2 6.9 2.1 0.0 0.4 2.0 45.0 0.0 0.0 16.2 1.2 13.0 0.4 0.0 24.2 25.9 0.0 0.1 0.8 0.2 2.3 0.0 5.4 0.0 3.5 3.2 10.6 0.0 0.7 0.4 0.9 0.7 0.0 3.9 0.0 6.6 0.0 0.0 103.9 10.1 5.6 0.2 0.0 0.1 0.0 0.1 5.1 0.0 3.9 1.4 2.5 0.0 0.0 0.0 2.4 0.1 0.1 0.4 48.4 7.0 0.0 9.0 1.9 0.0 0.1 0.0 19.8 0.0 0.0 0.0 0.0 26.4 0.0 2.1 0.4 45.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.0 0.0 5.5 0.2 0.0 16.2 CYP21A2 "CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B" ENSG00000231852 "Cytochrome P450 family 21 subfamily A member 2" P08686 6 32038265-32041670 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Steroidogenesis "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "adrenal gland: 170.9" "Cell line enhanced" "Detected in some" "HDLM-2: 11.5;Hep G2: 1.8;Karpas-707: 3.1" "Cancer enhanced" "Detected in some" "liver cancer: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA048979, HPA053371" Enhanced "Intracellular and membrane" "HPA048979: AB_2680584, HPA053371: AB_2682131" "unprognostic (1.03e-2)" "unprognostic (1.65e-1)" "unprognostic (1.02e-4)" "unprognostic (2.58e-1)" "unprognostic (2.97e-1)" "unprognostic (2.93e-2)" "unprognostic (2.76e-2)" "unprognostic (8.75e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (6.67e-7)" "unprognostic (7.39e-2)" "unprognostic (5.24e-2)" "unprognostic (1.09e-1)" "unprognostic (1.82e-1)" 0.1 170.9 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 6.7 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.3 7.4 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 3.6 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.5 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CYP24A1 "CP24, CYP24, P450-CC24" ENSG00000019186 "Cytochrome P450 family 24 subfamily A member 1" Q07973 20 54153449-54173973 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 38.8;lymphoid tissue: 25.8;urinary bladder: 31.2" "Group enriched" "Detected in some" 16 "A549: 92.9;Hep G2: 27.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 1.1;memory CD8 T-cell: 2.0" "Lineage enriched" "Detected in single" 20 "T-cells: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA022261, HPA063771" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA022261: AB_1847427, HPA063771: " "unprognostic (1.19e-7)" "unprognostic (1.73e-1)" "unprognostic (2.24e-2)" "unprognostic (7.69e-3)" "unprognostic (3.30e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-2)" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (5.37e-3)" "unprognostic (1.23e-1)" "unprognostic (6.05e-2)" "unprognostic (5.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.12e-1)" 0.1 0.1 0.4 0.2 0.7 0.0 2.5 0.1 0.4 2.5 0.1 0.0 0.3 0.0 11.2 0.4 4.4 0.3 0.0 0.1 0.4 0.8 38.8 0.3 1.6 0.1 0.2 0.0 0.1 0.1 0.0 0.7 7.0 0.3 7.0 0.0 0.1 0.3 1.5 0.1 1.0 0.1 0.6 0.2 0.1 0.1 0.3 0.0 0.4 1.4 5.9 25.8 31.2 14.4 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 92.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.0 0.7 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 1.5 0.3 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.7 0.1 0.4 0.4 0.8 0.2 0.0 0.3 0.0 CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 149.0" "Cell line enhanced" "Detected in some" "Hep G2: 72.6;HSkMC: 13.9;RPTEC TERT1: 18.5;SK-MEL-30: 29.8;WM-115: 11.6" "Cancer enhanced" "Detected in all" "liver cancer: 176.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 38.2;neutrophil: 30.6" "Group enriched" "Detected in many" 20 "granulocytes: 30.6;monocytes: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059155 Enhanced Supported Mitochondria Mitochondria "HPA059155: " "prognostic favourable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favourable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 14.4 12.3 6.3 4.7 13.4 0.7 5.5 2.4 7.5 6.5 21.9 16.9 24.9 21.0 5.0 5.4 3.5 9.2 5.1 6.9 8.3 6.2 12.6 149.0 22.4 5.6 19.9 5.7 9.5 2.4 6.3 7.1 2.0 12.1 11.6 6.0 15.1 10.0 21.5 10.0 3.9 36.8 5.0 18.8 3.1 3.5 3.7 15.7 3.7 3.1 4.0 7.6 5.5 5.7 0.1 1.7 30.6 38.2 0.0 0.1 10.0 0.0 0.0 0.7 0.0 1.3 0.8 0.1 0.8 3.0 1.0 2.1 3.6 0.1 0.0 1.5 2.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.1 72.6 4.2 0.1 0.0 13.9 0.1 0.0 0.0 1.4 0.0 0.0 2.0 0.0 0.0 0.1 0.8 0.1 0.0 0.7 0.1 18.5 0.0 0.0 0.0 0.0 0.0 29.8 0.5 0.7 1.6 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 11.6 0.0 38.2 0.1 0.0 4.3 0.0 0.1 0.0 0.1 1.7 0.0 0.0 0.0 30.6 0.0 0.3 0.2 0.0 10.0 6.3 13.4 2.4 7.5 8.3 6.2 19.9 5.7 12.1 15.7 CYP27C1 FLJ16008 ENSG00000186684 "Cytochrome P450 family 27 subfamily C member 1" Q4G0S4 2 127184120-127220078 "Enzymes, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 10.6" "Cell line enhanced" "Detected in many" "HaCaT: 8.6;HDLM-2: 12.4;TIME: 12.5;U-138 MG: 12.7;U-251 MG: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA062460, HPA068731" Enhanced Vesicles Vesicles "HPA062460: , HPA068731: " "unprognostic (1.90e-1)" "unprognostic (4.07e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-2)" "unprognostic (3.03e-1)" "unprognostic (7.75e-3)" "unprognostic (3.48e-1)" "unprognostic (2.31e-3)" "unprognostic (4.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.81e-3)" "unprognostic (1.11e-1)" "unprognostic (6.29e-4)" "unprognostic (3.49e-4)" "unprognostic (1.83e-1)" "unprognostic (4.27e-2)" "unprognostic (8.64e-2)" 2.7 1.0 0.6 2.4 2.4 0.8 0.6 0.4 1.8 5.2 1.9 1.5 0.4 0.5 1.3 0.8 4.4 1.0 1.5 2.0 0.4 0.9 0.4 0.4 0.4 0.6 2.9 0.4 0.4 0.4 0.0 0.4 0.4 0.7 2.2 0.7 4.2 0.4 1.5 0.8 10.6 1.0 0.4 0.4 0.4 0.5 0.7 3.6 0.4 0.4 2.2 1.6 2.7 4.5 1.5 1.3 3.6 1.0 1.8 1.4 0.2 1.3 3.9 2.0 0.2 0.1 0.0 0.2 0.5 3.6 2.0 0.9 0.1 3.0 0.2 0.1 2.3 8.6 3.2 1.8 0.6 12.4 1.5 0.0 2.2 0.1 0.0 0.1 0.1 0.1 0.1 0.5 1.2 0.5 0.1 0.5 2.3 0.1 0.3 0.1 4.4 1.1 0.1 0.2 0.0 6.5 1.1 0.1 0.7 5.5 0.0 0.0 0.2 0.1 12.5 12.7 2.2 6.2 8.3 0.2 0.1 0.1 0.1 0.1 0.9 2.4 1.0 0.7 1.2 0.7 1.0 0.9 1.0 0.8 0.3 1.5 1.1 1.4 3.6 1.8 0.7 1.3 0.8 0.2 0.6 2.4 0.4 1.3 0.4 0.9 2.9 0.4 0.7 3.6 CYP2A13 "CPAD, CYP2A" ENSG00000197838 "Cytochrome P450 family 2 subfamily A member 13" Q16696 19 41088472-41096195 "Enzymes, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 30.7" "Cell line enhanced" "Detected in some" "HaCaT: 2.1;NTERA-2: 1.5" "Cancer enriched" "Detected in single" 5 "liver cancer: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046713, HPA047262" Supported "Intracellular and membrane" "HPA046713: , HPA047262: " "unprognostic (9.79e-2)" "unprognostic (1.00e-1)" "unprognostic (4.51e-3)" "unprognostic (4.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.49e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.1 0.0 0.1 0.1 0.0 30.7 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 CYP2A7 CYP2A ENSG00000198077 "Cytochrome P450 family 2 subfamily A member 7" P20853 19 40875439-40882752 "Enzymes, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 134 "liver: 53.7" "Cell line enhanced" "Detected in single" "HL-60: 1.9" "Group enriched" "Detected in some" 238 "breast cancer: 9.2;liver cancer: 25.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033510, HPA046713, HPA047262" Enhanced "Intracellular and membrane" "CAB033510: AB_782366, HPA046713: , HPA047262: " "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (2.65e-3)" "unprognostic (8.89e-2)" "unprognostic (1.39e-2)" "unprognostic (3.95e-1)" "unprognostic (9.21e-2)" "unprognostic (8.71e-2)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94853205 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 47.7;liver: 76.4" "Cell line enhanced" "Detected in some" "CACO-2: 1.8;RPMI-8226: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA015066 Supported "Intracellular and membrane" "HPA015066: AB_1847433" "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 30.0 0.0 0.0 14.7 0.0 0.0 1.0 0.0 3.7 0.0 0.0 0.0 0.0 76.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 47.7 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 CYP2C8 CPC8 ENSG00000138115 "Cytochrome P450 family 2 subfamily C member 8" P10632 10 95036772-95069497 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 131 "liver: 247.5" "Cell line enhanced" "Detected in some" "Daudi: 1.7;HL-60: 2.7;SiHa: 2.9;U-266/70: 2.9;U-266/84: 2.2" "Cancer enriched" "Detected in some" 82 "liver cancer: 102.3" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 9 "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 9 "T-cells: 1.8" "HPA013547, HPA013970, HPA015066" Enhanced "Intracellular and membrane" "HPA013547: AB_1847435, HPA013970: AB_1847434, HPA015066: AB_1847433" "unprognostic (3.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-2)" "unprognostic (1.80e-3)" "unprognostic (4.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "prognostic favourable (9.82e-4)" "unprognostic (2.85e-1)" "unprognostic (1.44e-3)" "unprognostic (2.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.39e-1)" "unprognostic (4.05e-4)" 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.1 0.1 0.2 0.3 247.5 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.6 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 1.1 0.2 0.0 0.2 0.0 0.7 1.0 0.0 1.0 0.5 2.7 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.4 0.3 0.7 0.1 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 2.9 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.9 2.2 1.1 0.0 0.9 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94989391 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 233.0" "Cell line enhanced" "Detected in some" "HL-60: 3.4;NB-4: 1.7;RPMI-8226: 2.5;SiHa: 1.6" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, CAB016123" Enhanced "Intracellular and membrane" "CAB016123: AB_629363, HPA015066: AB_1847433" "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favourable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 45.8 0.0 0.0 13.6 0.0 0.6 1.1 0.0 1.0 0.0 0.0 0.0 0.5 233.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 43.8 0.0 0.0 0.1 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.7 0.4 0.0 0.0 0.3 2.5 0.4 0.0 0.1 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 CYP2D6 "CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D" ENSG00000100197 "Cytochrome P450 family 2 subfamily D member 6" P10635 22 42126499-42130906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 78.0" "Cell line enhanced" "Detected in some" "Hep G2: 4.3;HMC-1: 6.0;REH: 3.5;T-47d: 2.3;U-266/70: 4.2" "Cancer enriched" "Detected in many" 35 "liver cancer: 90.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045223 Enhanced Approved "Golgi apparatus" "Golgi apparatus" "HPA045223: AB_10962927" "unprognostic (4.40e-3)" "unprognostic (7.68e-3)" "unprognostic (5.45e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.29e-4)" "unprognostic (3.83e-2)" "unprognostic (7.27e-3)" "unprognostic (1.13e-1)" "unprognostic (1.71e-1)" "unprognostic (4.03e-4)" "unprognostic (2.11e-2)" "unprognostic (5.61e-5)" "unprognostic (3.01e-1)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (4.82e-5)" 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 2.2 0.1 0.1 3.5 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 78.0 0.1 0.1 0.1 0.1 0.5 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 11.2 0.1 0.1 0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 4.3 0.0 0.1 6.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.2 0.0 0.6 0.2 3.5 0.0 1.1 0.0 0.0 0.1 0.3 1.2 0.1 0.0 2.3 0.0 0.0 0.0 1.6 0.0 0.3 4.2 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "liver: 802.4" "Cell line enhanced" "Detected in many" "HaCaT: 9.6;HL-60: 7.4;HMC-1: 7.9;NB-4: 20.2" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "MAIT T-cell: 3.9;myeloid DC: 9.1" "Group enriched" "Detected in many" 17 "dendritic cells: 9.1;T-cells: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced "Intracellular and membrane" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.6 0.3 0.1 0.1 0.2 0.7 0.0 0.1 0.3 0.8 0.2 1.3 0.1 0.1 0.1 0.3 802.4 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.1 0.1 0.3 0.1 0.0 0.2 0.1 1.1 0.1 0.6 0.1 0.1 0.1 0.4 0.1 0.3 0.1 0.1 0.2 0.2 1.5 0.1 0.1 0.0 9.1 0.0 0.3 0.2 3.9 0.3 0.1 0.0 0.3 0.9 3.2 1.8 0.6 1.4 3.9 0.0 0.3 0.0 2.3 1.2 0.2 0.4 9.6 0.0 0.2 0.3 0.2 1.3 1.5 0.1 1.1 0.5 7.4 7.9 0.9 0.2 0.0 0.6 0.0 0.4 0.3 0.9 0.6 0.5 20.2 5.5 0.3 0.3 5.4 0.0 1.7 0.0 0.0 0.0 3.7 0.0 0.6 0.2 0.8 0.0 1.2 0.4 2.0 0.9 2.0 0.8 2.7 1.3 6.3 0.1 0.0 0.0 0.0 0.1 0.0 3.9 0.0 1.7 1.0 9.1 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.0 0.3 0.1 0.2 0.6 0.3 0.1 0.1 0.1 0.1 0.3 0.1 CYP2R1 ENSG00000186104 "Cytochrome P450 family 2 subfamily R member 1" Q6VVX0 11 14877440-14892252 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042949 Approved "Intracellular and membrane" "HPA042949: " "unprognostic (1.62e-2)" "unprognostic (1.82e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-3)" "unprognostic (2.67e-1)" "unprognostic (2.19e-1)" "unprognostic (3.23e-2)" "unprognostic (7.73e-2)" "unprognostic (1.70e-1)" "unprognostic (3.90e-2)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "prognostic unfavourable (2.86e-4)" "unprognostic (1.01e-1)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "unprognostic (1.44e-2)" 5.4 4.4 3.5 7.4 6.5 6.4 10.1 7.7 6.8 5.4 8.6 4.2 4.6 10.8 4.6 7.9 10.3 4.3 6.9 6.9 4.3 3.4 6.4 9.1 6.3 6.7 5.3 5.8 4.9 12.0 5.1 7.7 2.7 4.7 8.1 8.0 5.6 10.2 5.5 6.2 15.8 12.6 8.7 5.4 9.3 9.5 14.9 6.2 9.3 5.2 9.7 9.1 7.7 6.8 5.6 3.5 4.2 3.8 3.2 8.8 2.0 4.8 2.9 2.9 1.2 1.3 2.1 0.0 1.6 0.9 0.9 1.0 3.4 5.5 6.0 1.3 0.3 0.0 1.0 2.2 0.4 4.9 4.6 2.6 3.3 0.2 4.5 4.6 2.8 2.0 8.6 0.0 3.6 1.1 3.9 21.0 0.6 1.2 5.0 9.2 2.7 2.8 3.6 2.2 8.8 1.1 0.5 2.4 3.8 3.6 4.4 4.0 3.2 1.7 3.0 2.9 3.6 1.8 2.1 10.5 12.1 7.1 4.1 6.0 2.6 4.2 3.7 2.7 5.9 3.2 8.8 3.0 4.7 3.5 3.0 5.6 6.8 5.6 0.6 3.2 3.8 3.5 5.6 2.0 3.5 6.5 7.7 6.8 4.3 3.4 5.3 5.8 4.7 6.2 CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193049-41207539 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 33.1;gallbladder: 29.1;intestine: 62.7;stomach 1: 45.9" "Cell line enhanced" "Detected in many" "A549: 37.2;CACO-2: 19.2;HaCaT: 19.9;NTERA-2: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "classical monocyte: 9.5;myeloid DC: 33.1" "Group enriched" "Detected in many" 121 "dendritic cells: 33.1;monocytes: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA049227: , HPA069248: " "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavourable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" 1.2 0.8 0.8 2.3 1.0 0.5 0.6 0.1 1.0 1.7 18.3 1.2 0.5 37.6 0.3 0.9 10.1 2.4 29.1 1.0 1.4 1.6 0.9 2.1 3.8 3.3 5.6 0.4 0.8 0.6 0.0 0.9 1.6 4.5 0.9 7.2 1.1 3.8 0.3 0.1 2.0 62.7 0.6 1.1 4.0 45.9 0.5 1.2 2.6 0.4 15.8 21.0 3.2 2.7 0.0 33.1 0.0 9.5 0.0 0.1 3.9 1.4 37.2 0.0 0.0 0.0 0.0 1.8 0.2 0.3 0.4 0.1 19.2 5.4 0.1 4.4 0.2 19.9 6.5 10.1 0.1 0.0 0.1 5.0 2.0 6.9 7.9 0.0 0.1 0.3 0.5 0.5 0.3 0.3 2.2 0.1 0.0 0.7 0.1 0.1 28.2 4.8 0.1 0.0 0.3 0.6 7.9 0.0 0.2 3.7 0.0 0.0 4.9 1.9 4.2 0.0 1.6 0.7 0.0 0.2 0.0 0.0 0.2 0.8 0.0 0.0 9.5 0.0 0.0 2.3 0.1 0.0 0.0 0.0 33.1 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.0 3.9 0.8 1.0 0.1 1.0 1.4 1.6 5.6 0.4 4.5 1.2 CYP2U1 SPG49 ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931369-107953457 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 122.7" "Cell line enhanced" "Detected in many" "ASC diff: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: , HPA046754: , HPA064827: " "unprognostic (3.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "unprognostic (5.16e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-3)" "unprognostic (3.19e-1)" "unprognostic (8.97e-3)" "unprognostic (5.41e-3)" "unprognostic (3.02e-1)" "prognostic favourable (2.75e-5)" "prognostic unfavourable (6.97e-4)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 8.6 7.9 7.7 4.4 9.1 0.4 7.3 11.3 9.2 7.8 7.3 7.0 4.1 4.0 9.5 4.6 6.3 9.8 6.6 8.8 7.1 7.9 6.4 6.8 6.6 6.7 8.3 5.2 12.0 2.6 10.3 8.1 2.7 7.8 12.4 4.7 8.6 4.5 11.0 4.3 3.1 6.0 12.3 7.0 8.5 4.6 3.9 7.4 122.7 4.7 3.5 5.4 7.3 5.3 2.6 2.7 0.7 5.9 1.6 1.7 0.4 2.5 1.2 3.4 6.3 18.8 9.0 0.5 10.8 16.3 6.6 10.5 0.0 1.7 6.9 0.8 6.4 0.1 5.3 4.0 10.4 1.9 1.6 1.4 2.4 0.3 7.5 2.0 0.0 10.1 3.4 3.1 2.1 2.5 0.1 3.3 5.5 1.8 7.4 0.0 3.5 3.0 4.2 4.1 0.0 2.1 4.3 6.7 5.0 2.7 4.7 11.5 2.3 1.0 6.8 4.3 0.5 6.1 4.3 14.0 13.2 2.2 3.5 0.0 4.8 0.0 0.3 0.7 1.2 1.1 0.9 2.0 0.9 1.0 2.2 2.6 1.7 1.3 0.0 1.6 5.9 2.7 0.0 0.4 7.7 9.1 11.3 6.9 7.1 7.9 8.3 5.2 7.8 7.4 CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784265 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 45 "intestine: 145.3;liver: 464.6" "Cell line enhanced" "Detected in some" "BEWO: 4.1;NB-4: 4.4;RPMI-8226: 6.6;SCLC-21H: 2.5;SH-SY5Y: 4.9" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033671, HPA072245" Enhanced Uncertain Cytosol Cytosol "CAB033671: AB_782375, HPA072245: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" 0.1 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 145.3 0.1 0.1 56.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 464.6 0.1 0.1 0.1 0.1 0.1 6.8 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.2 126.7 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.2 0.6 0.2 0.6 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 1.9 0.4 0.0 1.2 0.0 0.4 0.0 0.5 0.0 0.5 0.0 0.1 4.4 0.3 0.0 0.0 2.1 6.6 0.0 0.4 2.5 4.9 0.4 0.0 0.0 0.1 0.0 0.8 0.0 0.0 1.3 0.0 0.7 0.0 0.7 0.1 0.7 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.6 0.6 0.0 0.2 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CYP3A43 ENSG00000021461 "Cytochrome P450 family 3 subfamily A member 43" Q9HB55 7 99828013-99866102 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 32.5" "Low cell line specificity" "Detected in some" "Cancer enriched" "Detected in single" 18 "liver cancer: 1.4" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "HPA066463, HPA072245" Enhanced Uncertain Cytosol Cytosol "HPA066463: , HPA072245: " "unprognostic (1.20e-3)" "unprognostic (4.74e-2)" "unprognostic (3.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.52e-1)" "prognostic favourable (3.41e-4)" "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "unprognostic (2.38e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.23e-2)" "unprognostic (6.46e-2)" "unprognostic (5.90e-2)" "unprognostic (3.10e-1)" "unprognostic (6.37e-4)" 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.2 0.9 0.1 0.0 0.1 0.1 0.1 0.0 0.2 32.5 0.1 0.1 0.1 0.1 0.1 8.0 0.0 2.2 0.1 0.1 1.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.6 0.5 1.6 0.6 0.3 0.6 0.2 0.1 0.0 0.9 0.3 1.1 0.2 0.2 0.0 0.1 0.2 0.2 1.2 0.7 1.5 0.2 0.3 1.3 0.2 0.0 0.7 0.2 0.5 0.9 1.4 1.3 0.3 0.9 1.3 0.0 0.7 0.0 0.0 0.5 1.0 1.0 0.0 0.0 0.0 0.6 0.4 0.0 0.9 0.0 0.2 0.7 1.6 0.5 0.4 0.6 1.7 0.0 0.5 0.0 1.6 0.5 0.2 1.1 0.7 1.1 1.2 0.1 0.8 0.4 0.2 1.5 0.6 0.4 0.6 0.2 0.3 0.3 0.3 0.2 0.1 0.6 0.5 0.5 1.6 0.3 0.2 0.5 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99680026 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 72.9;liver: 73.4;stomach 1: 21.3" "Cell line enhanced" "Detected in some" "A549: 3.1;CACO-2: 12.1;CAPAN-2: 8.1;Hep G2: 8.4" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA072245 Uncertain Cytosol Cytosol "HPA072245: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favourable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" 1.0 3.3 0.4 2.0 0.5 0.0 1.3 0.6 0.6 1.9 32.6 0.6 1.0 30.3 0.7 0.5 5.2 0.5 8.2 0.4 0.4 0.0 6.8 73.4 2.4 0.8 0.4 0.4 0.6 12.1 0.0 1.8 0.6 0.8 4.9 5.1 0.4 0.6 1.3 0.4 4.3 72.9 0.6 0.5 0.4 21.3 0.7 0.4 0.5 0.4 2.2 4.0 3.0 2.7 0.0 0.2 0.1 0.6 0.0 0.7 0.2 0.0 3.1 0.0 0.0 0.5 0.8 0.1 0.0 0.0 0.0 0.0 12.1 8.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.4 0.1 0.1 0.2 0.0 2.6 0.0 0.1 0.0 2.6 0.2 0.0 0.1 0.0 0.5 0.2 0.0 0.1 0.0 0.8 0.7 0.6 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.4 0.5 0.6 0.6 0.4 0.0 0.4 0.4 0.8 0.4 CYP3A7 "CP37, P450-HFLA" ENSG00000160870 "Cytochrome P450 family 3 subfamily A member 7" P24462 7 99684957-99735196 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "liver: 82.6" "Group enriched" "Detected in some" 5 "BEWO: 1.8;BJ hTERT+: 3.2;Hep G2: 6.2;HHSteC: 3.6;RT4: 1.9" "Cancer enriched" "Detected in some" 43 "liver cancer: 38.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA072245 Uncertain Cytosol Cytosol "HPA072245: " "unprognostic (8.10e-3)" "unprognostic (1.45e-1)" "unprognostic (3.12e-1)" "unprognostic (5.47e-2)" "unprognostic (1.73e-1)" "unprognostic (1.44e-1)" "unprognostic (4.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.34e-2)" "unprognostic (8.28e-2)" "unprognostic (8.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-11)" "unprognostic (2.02e-2)" "unprognostic (5.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.34e-3)" 0.1 0.4 0.1 0.1 0.0 0.0 2.6 0.1 0.1 0.0 0.7 0.0 0.0 0.1 0.3 0.1 0.2 0.0 3.9 0.0 0.1 0.0 2.8 82.6 0.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.4 1.8 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.2 3.6 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 CYP3A7-CYP3A51P ENSG00000282301 "CYP3A7-CYP3A51P readthrough" P24462 7 99685226-99735093 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "liver: 73.9" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.2;U-87 MG: 2.6" "Cell type enhanced" "Detected in single" "eosinophil: 1.1" "Low lineage specificity" "Detected in single" HPA072245 Uncertain Cytosol Cytosol "HPA072245: " 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.1 0.0 3.5 0.0 0.0 1.1 73.9 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 1.1 0.0 0.0 0.5 0.0 0.3 0.5 1.6 0.5 0.2 4.2 0.0 0.6 0.2 0.0 0.0 0.0 1.3 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.4 0.9 1.3 1.9 0.0 0.0 0.4 0.3 0.4 0.4 0.0 0.3 0.0 0.4 1.0 0.1 0.2 1.1 0.5 0.2 0.2 0.1 0.4 1.4 0.0 0.0 0.3 0.2 0.0 0.5 0.6 0.0 0.1 0.4 0.3 0.5 0.5 0.6 0.9 0.7 0.1 2.6 0.7 0.1 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 CYP4B1 ENSG00000142973 "Cytochrome P450 family 4 subfamily B member 1" P13584 1 46757838-46819413 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 92.0" "Cell line enriched" "Detected in some" 8 "RT4: 79.5" "Cancer enhanced" "Detected in many" "urothelial cancer: 56.9" "Region enhanced" "Detected in single" "midbrain: 1.7" "Cell type enriched" "Detected in single" 11 "memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA004331 Approved Supported Vesicles Vesicles "HPA004331: AB_1078616" "unprognostic (2.29e-2)" "prognostic favourable (5.99e-4)" "unprognostic (7.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.28e-1)" "unprognostic (8.31e-2)" "unprognostic (1.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.65e-1)" "unprognostic (2.59e-1)" "unprognostic (6.12e-2)" "unprognostic (5.46e-2)" "unprognostic (7.33e-2)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.22e-3)" "unprognostic (6.69e-3)" 41.6 2.2 0.0 0.6 0.1 0.3 45.5 0.1 0.3 9.5 6.7 0.1 7.2 0.7 2.1 2.8 17.9 18.5 0.8 13.5 0.0 0.0 1.4 0.2 92.0 1.5 1.7 0.1 3.3 0.9 0.5 4.8 0.9 0.8 15.4 0.5 2.8 5.0 6.9 14.4 10.4 3.4 6.8 3.5 0.5 3.0 1.7 0.1 0.7 12.7 4.5 5.7 36.5 18.9 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.2 0.0 0.0 1.7 0.1 0.8 0.1 CYP4F11 ENSG00000171903 "Cytochrome P450 family 4 subfamily F member 11" Q9HBI6 19 15912367-15934867 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 88.6" "Cell line enhanced" "Detected in some" "A-431: 7.5;CAPAN-2: 29.9;EFO-21: 11.2;Hep G2: 14.4;RPMI-8226: 7.8;RT4: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "intermediate monocyte: 1.2" "Low lineage specificity" "Detected in single" "HPA017265, CAB033648, HPA058960" Enhanced "Intracellular and membrane" "CAB033648: AB_2088410, HPA017265: AB_1847451, HPA058960: " "prognostic favourable (4.05e-4)" "unprognostic (4.12e-2)" "unprognostic (1.79e-1)" "unprognostic (5.99e-2)" "unprognostic (5.92e-3)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (2.33e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (9.28e-4)" "unprognostic (4.44e-2)" "unprognostic (9.50e-3)" "unprognostic (2.14e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-2)" "unprognostic (4.64e-2)" 0.4 2.2 3.6 0.5 4.4 0.5 1.7 1.8 5.4 1.1 2.5 4.4 0.0 7.5 0.5 11.8 7.9 2.2 12.9 0.4 3.9 1.4 4.9 88.6 2.4 0.4 2.1 3.8 0.3 3.5 0.2 0.6 0.2 8.3 2.4 1.9 0.6 2.6 3.4 0.5 0.8 15.7 0.2 9.7 0.9 2.7 1.0 3.0 0.0 2.2 2.8 1.8 4.8 2.0 0.1 0.1 0.8 1.2 0.0 0.2 0.1 7.5 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.1 11.2 0.0 0.9 0.0 3.9 0.0 0.0 0.0 0.0 2.3 14.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 6.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.1 7.8 2.0 8.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.1 0.1 0.1 0.3 0.1 0.2 0.9 0.0 0.8 0.5 0.0 0.1 1.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.7 0.1 0.0 0.1 3.6 4.4 1.8 5.4 3.9 1.4 2.1 3.8 8.3 3.0 CYP4F2 ENSG00000186115 "Cytochrome P450 family 4 subfamily F member 2" P78329 19 15878023-15898120 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 69.1;liver: 102.9" "Cell line enriched" "Detected in some" 4 "Hep G2: 8.8" "Cancer enriched" "Detected in some" 9 "liver cancer: 29.6" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 12 "basophil: 8.5" "Lineage enriched" "Detected in single" 86 "granulocytes: 8.5" "HPA014048, HPA017265, HPA058960" Supported "Intracellular and membrane" "HPA014048: AB_1847452, HPA017265: AB_1847451, HPA058960: " "unprognostic (7.46e-3)" "unprognostic (3.58e-1)" "unprognostic (3.01e-1)" "unprognostic (9.39e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-2)" "unprognostic (4.55e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (8.69e-4)" "unprognostic (3.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.79e-3)" 0.1 0.1 0.2 0.5 0.1 0.0 0.2 0.1 0.2 0.2 10.1 0.2 0.1 24.5 0.1 8.8 0.2 0.1 1.8 0.1 0.2 0.1 11.9 102.9 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.2 1.9 0.0 0.1 0.1 0.2 0.1 0.5 69.1 0.1 0.2 0.2 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.4 0.3 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.7 0.1 0.3 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.1 0.0 0.2 8.8 0.0 0.9 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.5 0.1 0.1 0.3 0.6 0.8 0.1 0.4 0.4 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.1 CYP4F3 "CYP4F, LTB4H" ENSG00000186529 "Cytochrome P450 family 4 subfamily F member 3" Q08477 19 15640897-15662825 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 159.2" "Cell line enhanced" "Detected in some" "A549: 5.3;CAPAN-2: 24.2;HaCaT: 11.1;Hep G2: 13.2" "Cancer enhanced" "Detected in many" "liver cancer: 30.6" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 68 "neutrophil: 33.1" "Lineage enriched" "Detected in single" 166 "granulocytes: 33.1" HPA058960 Approved "HPA058960: " "unprognostic (1.73e-2)" "unprognostic (9.70e-3)" "unprognostic (1.21e-1)" "unprognostic (1.16e-3)" "unprognostic (5.40e-1)" "unprognostic (1.57e-1)" "unprognostic (7.15e-3)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.32e-1)" "unprognostic (1.59e-3)" "unprognostic (2.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "unprognostic (2.07e-1)" 0.4 0.1 0.3 0.3 1.5 24.8 0.1 0.1 2.2 2.1 3.4 6.5 0.0 3.1 0.1 0.4 8.6 0.3 19.8 0.2 0.8 0.2 23.7 159.2 0.7 0.0 0.4 1.9 0.1 0.2 0.0 0.2 0.0 1.6 0.3 0.5 0.0 1.3 0.1 0.1 1.2 13.4 0.1 1.0 2.6 1.7 0.2 1.8 0.0 0.1 1.1 0.8 1.8 2.7 0.0 0.0 33.1 0.1 0.0 0.0 0.0 0.2 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 24.2 0.1 0.1 0.0 11.1 0.0 0.1 0.0 0.4 0.0 0.1 2.3 13.2 0.0 0.2 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.1 2.2 0.8 0.2 0.4 1.9 1.6 1.8 CYP4F8 ENSG00000186526 "Cytochrome P450 family 4 subfamily F member 8" P98187 19 15615218-15630638 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 155 "ductus deferens: 265.6;seminal vesicle: 360.6" "Group enriched" "Detected in some" 9 "RT4: 1.6;SK-BR-3: 4.5" "Group enriched" "Detected in some" 31 "breast cancer: 2.5;prostate cancer: 3.3;urothelial cancer: 10.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Approved "HPA058960: " "unprognostic (1.70e-2)" "unprognostic (5.46e-3)" "unprognostic (3.21e-2)" "unprognostic (3.97e-6)" "unprognostic (3.51e-3)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (8.25e-2)" "unprognostic (1.15e-2)" "unprognostic (1.02e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 265.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 360.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 4.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP4V2 CYP4AH1 ENSG00000145476 "Cytochrome P450 family 4 subfamily V member 2" Q6ZWL3 4 186191520-186213456 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Monooxygenase, Oxidoreductase" "Corneal dystrophy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 64.7" "Cell line enhanced" "Detected in many" "Karpas-707: 12.9;SK-MEL-30: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029122 Approved Approved "Nuclear speckles" "Nuclear speckles" "HPA029122: AB_10601806" "unprognostic (1.65e-1)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "prognostic favourable (5.86e-4)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "prognostic favourable (1.85e-4)" "unprognostic (6.66e-2)" "unprognostic (5.84e-2)" "unprognostic (2.05e-1)" "unprognostic (6.49e-2)" "unprognostic (9.89e-2)" "prognostic favourable (1.49e-7)" "unprognostic (3.25e-2)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" 6.6 16.6 7.8 5.0 12.4 1.6 5.5 8.9 7.5 6.7 8.0 8.9 4.9 11.4 5.7 4.2 5.2 6.2 13.7 7.4 7.7 4.6 21.6 64.7 7.3 4.1 7.7 9.0 6.3 12.1 30.8 16.1 3.0 6.7 5.6 8.2 19.1 6.2 9.1 3.3 2.8 14.7 6.4 7.0 7.5 5.2 3.2 7.4 4.4 11.9 2.1 3.8 8.0 5.1 2.3 2.5 0.0 6.2 1.3 4.0 1.5 2.6 1.8 0.6 0.0 11.1 4.6 0.1 3.7 7.9 1.4 1.9 0.0 10.7 1.0 0.5 2.4 1.3 1.3 1.1 0.4 6.4 1.3 4.0 0.4 0.5 3.3 2.2 2.0 4.1 0.5 1.4 0.6 0.1 1.6 12.9 4.6 2.2 2.4 0.6 1.4 0.0 2.1 0.5 1.1 4.5 5.1 2.8 4.0 0.9 0.0 19.0 1.9 3.5 4.2 2.9 0.7 3.3 1.6 0.0 0.0 0.5 8.8 8.2 3.5 0.0 1.2 0.0 4.0 4.1 2.5 1.0 2.5 3.4 1.5 2.3 2.7 2.3 0.0 1.3 6.2 2.5 2.1 1.5 7.8 12.4 8.9 7.5 7.7 4.6 7.7 9.0 6.7 7.4 CYP4X1 MGC40051 ENSG00000186377 "Cytochrome P450 family 4 subfamily X member 1" Q8N118 1 47023568-47050751 "Enzymes, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 38.1" "Cell line enhanced" "Detected in some" "ASC diff: 3.6;CACO-2: 6.1;HEK 293: 2.5;NTERA-2: 2.8;SCLC-21H: 3.7;T-47d: 13.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA017661 Approved "HPA017661: AB_2669633" "unprognostic (1.19e-1)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (1.78e-2)" "unprognostic (9.88e-2)" "unprognostic (1.56e-3)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (2.76e-2)" "unprognostic (3.03e-2)" "unprognostic (1.79e-3)" "unprognostic (3.65e-2)" "unprognostic (8.56e-2)" "unprognostic (5.03e-2)" 7.9 3.6 9.0 1.1 14.9 0.5 16.0 7.1 16.9 38.1 2.0 1.6 2.5 2.1 3.6 3.2 12.0 9.7 2.0 6.7 4.8 10.6 6.3 10.0 8.9 2.0 3.3 13.5 1.7 2.0 2.0 4.1 1.5 7.8 8.0 2.3 17.6 23.7 3.4 4.5 5.0 1.8 2.4 2.0 1.0 14.3 4.2 0.9 0.0 4.0 6.9 8.8 3.9 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.2 0.1 0.0 0.1 0.0 0.0 6.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.5 0.0 0.6 0.2 3.7 0.0 0.0 0.3 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 14.9 7.1 16.9 4.8 10.6 3.3 13.5 7.8 0.9 CYP51A1 "CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1" ENSG00000001630 "Cytochrome P450 family 51 subfamily A member 1" Q16850 7 92112151-92142952 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041325, HPA043508" Enhanced Enhanced "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA041325: AB_2677411, HPA043508: AB_2678520" "unprognostic (6.68e-2)" "prognostic unfavourable (6.12e-4)" "unprognostic (3.48e-2)" "unprognostic (1.18e-2)" "unprognostic (7.82e-2)" "unprognostic (3.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (9.84e-2)" "unprognostic (1.36e-1)" "unprognostic (9.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.59e-9)" "unprognostic (1.82e-1)" "unprognostic (2.73e-1)" "unprognostic (5.13e-2)" "unprognostic (1.09e-3)" 10.3 27.0 16.7 8.1 22.1 10.5 15.5 13.3 32.0 11.8 21.1 32.9 6.3 33.1 9.1 15.3 23.4 7.1 10.3 9.9 18.6 20.8 18.6 80.9 22.2 5.0 17.2 13.7 21.0 20.2 32.4 11.9 8.8 47.1 18.2 16.9 17.1 11.0 7.7 4.3 12.8 28.8 8.3 43.7 7.3 18.1 35.7 19.5 2.3 14.1 18.7 10.0 9.0 13.2 14.2 14.1 3.5 13.9 6.7 10.7 7.1 24.6 12.1 30.5 19.5 21.5 35.2 4.3 8.4 25.4 10.9 29.8 29.0 45.1 21.5 13.3 14.4 21.6 26.6 53.0 12.7 9.0 18.8 6.2 12.9 21.8 29.3 12.6 9.3 25.5 24.1 42.5 44.8 11.1 23.2 49.6 12.8 25.2 2.7 11.7 22.8 12.1 8.7 6.3 48.5 49.4 41.8 21.5 14.4 17.8 35.4 26.0 12.8 15.2 13.2 15.0 16.7 21.6 10.9 16.9 15.0 19.6 11.5 16.8 19.1 1.8 9.7 3.5 10.7 13.9 7.1 14.2 7.6 8.4 14.1 10.7 7.2 9.2 1.5 6.7 8.3 12.4 5.8 7.1 16.7 22.1 13.3 32.0 18.6 20.8 17.2 13.7 47.1 19.5 CYP7B1 SPG5A ENSG00000172817 "Cytochrome P450 family 7 subfamily B member 1" O75881 8 64587763-64798761 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease mutation, Hereditary spastic paraplegia, Intrahepatic cholestasis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HSkMC: 16.5;SH-SY5Y: 6.1;WM-115: 12.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 36 "basophil: 6.4;eosinophil: 6.2" "Lineage enriched" "Detected in single" 36 "granulocytes: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017761 Uncertain "HPA017761: AB_1847455" "unprognostic (3.19e-2)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (6.89e-3)" "unprognostic (1.07e-1)" "unprognostic (5.80e-3)" "unprognostic (3.80e-1)" "unprognostic (5.50e-2)" "unprognostic (6.11e-3)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.19e-2)" "unprognostic (1.87e-2)" "unprognostic (2.38e-3)" "unprognostic (4.00e-1)" "unprognostic (3.04e-3)" "unprognostic (6.75e-3)" 10.1 8.5 5.0 7.5 12.2 0.8 9.8 2.1 10.8 8.7 3.8 20.7 3.5 2.4 4.1 3.9 10.8 5.4 8.0 6.6 5.8 4.2 10.0 24.6 11.0 5.7 5.0 7.8 5.6 8.2 31.0 4.4 1.7 13.5 5.8 4.8 7.3 6.6 7.1 1.8 6.7 3.5 6.1 12.6 19.1 3.9 3.2 7.5 0.2 16.2 5.5 3.8 8.4 10.1 0.0 0.1 6.4 0.0 0.0 0.1 0.0 1.8 0.8 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.4 0.0 2.1 6.1 0.0 0.1 2.6 0.0 1.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 6.4 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.0 12.2 2.1 10.8 5.8 4.2 5.0 7.8 13.5 7.5 DAO DAMOX ENSG00000110887 "D-amino acid oxidase" P14920 12 108858932-108901043 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "brain: 37.0;kidney: 39.0;liver: 64.2" "Cell line enhanced" "Detected in some" "AF22: 1.3;ASC TERT1: 1.3;BEWO: 1.5;Hep G2: 4.4;HL-60: 1.7;HMC-1: 1.3;RH-30: 1.2" "Cancer enriched" "Detected in some" 9 "liver cancer: 13.2" "Group enriched" "Detected in many" 5 "cerebellum: 37.0;pons and medulla: 31.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "cerebellum: 74.4;pons and medulla: 21.1" "Low region specificity" "Detected in many" "HPA038653, HPA038654" Enhanced "Intracellular and membrane" "HPA038653: AB_10673016, HPA038654: AB_10673285" "unprognostic (1.50e-1)" "unprognostic (5.61e-2)" "unprognostic (1.43e-1)" "unprognostic (2.91e-1)" "unprognostic (2.18e-1)" "unprognostic (2.99e-2)" "unprognostic (2.31e-3)" "unprognostic (8.02e-2)" "unprognostic (2.88e-2)" "unprognostic (9.59e-2)" "unprognostic (9.07e-2)" "unprognostic (7.13e-2)" "prognostic favourable (4.11e-4)" "unprognostic (3.44e-3)" "unprognostic (8.96e-2)" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" 0.3 0.2 0.0 0.2 2.7 0.2 0.2 37.0 0.7 0.2 0.9 11.5 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.8 0.9 39.0 64.2 0.3 0.2 6.4 0.5 0.2 0.3 0.2 0.0 0.2 31.2 0.2 1.1 0.0 0.2 0.2 0.2 0.2 0.2 0.3 35.9 0.2 0.2 0.2 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.3 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 1.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 37.0 0.5 0.8 0.9 6.4 0.5 31.2 0.4 DAPK1 "DAPK, ROCO3" ENSG00000196730 "Death associated protein kinase 1" P53355 9 87497228-87708633 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Apoptosis, Translation regulation" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 94.7" "Cell line enhanced" "Detected in many" "HMC-1: 38.7;HUVEC TERT2: 21.9;RPTEC TERT1: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.3;eosinophil: 6.9;intermediate monocyte: 11.9;myeloid DC: 4.0;non-classical monocyte: 11.7;plasmacytoid DC: 5.3" "Group enriched" "Detected in many" 55 "dendritic cells: 5.3;granulocytes: 6.9;monocytes: 11.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB037302, HPA040472, HPA048436" Approved Approved Centrosome Centrosome "CAB037302: AB_1078622, HPA040472: , HPA048436: " "unprognostic (2.55e-1)" "unprognostic (1.47e-1)" "prognostic unfavourable (2.48e-5)" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.75e-1)" "unprognostic (1.88e-2)" "unprognostic (5.77e-3)" "unprognostic (2.19e-2)" "unprognostic (2.77e-3)" "unprognostic (8.31e-3)" "unprognostic (8.76e-2)" "unprognostic (2.40e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-3)" 14.6 4.9 10.4 8.8 25.5 3.8 4.1 2.9 17.6 8.1 16.6 6.5 8.1 7.8 8.7 16.1 4.5 12.2 21.6 4.1 12.4 8.1 14.7 21.3 28.6 8.5 4.6 10.4 32.7 21.2 4.8 16.6 94.7 6.6 5.1 7.5 5.9 9.3 7.3 1.5 3.7 11.0 8.1 4.8 16.4 15.0 6.3 7.3 34.5 7.2 1.5 5.2 13.2 10.5 0.1 5.3 6.9 11.9 0.1 0.1 2.1 0.0 18.2 8.8 6.1 0.2 0.1 14.0 1.2 1.7 7.2 8.1 2.6 0.1 0.1 1.8 0.3 17.0 5.4 0.4 3.1 0.1 4.4 8.8 2.5 8.9 7.8 0.0 38.7 0.5 2.9 1.3 0.5 21.9 6.6 3.7 6.0 0.5 2.6 0.0 9.9 0.0 0.7 7.8 0.0 20.0 18.2 4.0 4.5 0.0 1.8 7.7 0.0 5.8 0.1 0.0 0.1 0.0 0.0 14.6 3.0 0.0 0.1 2.4 1.2 1.3 5.3 6.9 0.0 11.9 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 1.6 0.1 11.7 5.3 0.0 2.1 10.4 25.5 2.9 17.6 12.4 8.1 4.6 10.4 6.6 7.3 DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 51.8;skeletal muscle: 46.1" "Cell line enhanced" "Detected in many" "ASC diff: 10.0;HaCaT: 8.3;HMC-1: 17.0;MCF7: 8.6" "Cancer enriched" "Detected in many" 15 "thyroid cancer: 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 19.1;eosinophil: 51.8;neutrophil: 16.4" "Lineage enriched" "Detected in many" 23 "granulocytes: 51.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA071581: " "unprognostic (3.20e-2)" "unprognostic (4.07e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-3)" "unprognostic (2.88e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "prognostic favourable (5.63e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (8.51e-2)" "unprognostic (4.77e-7)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-3)" "unprognostic (9.07e-2)" 8.2 1.6 2.6 6.8 5.0 10.3 5.2 1.4 3.9 3.6 16.6 12.0 8.3 14.2 1.7 1.5 2.1 1.2 1.7 17.6 3.6 2.0 2.2 1.4 14.0 2.5 6.8 3.0 0.7 1.7 1.1 1.1 0.3 4.7 3.1 4.7 1.9 4.8 4.8 46.1 4.6 25.8 1.2 3.4 4.7 6.9 2.0 6.5 1.1 22.3 8.7 3.3 2.1 9.6 0.3 2.2 51.8 0.0 0.7 0.6 0.3 2.8 2.0 5.6 1.4 10.0 0.4 0.1 1.9 6.0 1.0 1.1 0.8 1.4 0.2 0.6 6.0 8.3 3.5 0.1 0.6 0.2 0.1 1.1 3.9 0.1 0.1 0.1 17.0 1.0 7.2 0.3 0.2 0.6 0.4 0.1 0.7 8.6 0.0 0.3 0.6 2.0 2.6 0.0 0.3 0.0 2.8 0.4 0.3 0.4 1.1 0.0 4.8 0.4 0.4 0.8 1.0 1.3 1.6 0.6 0.2 0.0 0.0 2.7 0.2 19.1 0.0 51.8 0.6 0.0 0.2 0.3 0.1 0.5 0.0 0.1 0.0 0.4 16.4 0.7 0.0 2.2 0.0 0.3 2.6 5.0 1.4 3.9 3.6 2.0 6.8 3.0 4.7 6.5 DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028569, HPA064809" Approved Approved Nucleoplasm Nucleoplasm "HPA028569: AB_10794319, HPA064809: " "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.34e-3)" "prognostic favourable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (2.37e-1)" "unprognostic (7.72e-3)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-3)" "unprognostic (7.64e-2)" "prognostic unfavourable (6.49e-4)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" 18.8 10.2 12.6 16.6 16.4 10.0 17.2 14.5 29.5 22.5 30.1 13.6 11.5 18.5 33.1 11.5 20.2 18.5 21.9 49.2 12.4 11.0 10.9 11.0 24.5 11.6 11.9 16.8 18.8 21.7 11.1 14.6 26.0 19.7 21.3 6.9 18.2 15.3 25.8 45.2 17.8 17.0 38.8 10.6 14.7 23.3 15.7 12.7 11.8 11.4 11.6 12.9 26.7 17.8 15.0 14.7 23.9 15.6 17.3 19.5 11.0 25.5 20.3 12.7 16.0 9.5 10.8 19.6 35.3 28.5 28.9 19.1 37.4 7.7 14.2 17.3 30.9 20.4 12.4 20.0 10.5 20.7 20.6 5.7 24.9 21.4 30.3 13.7 21.5 24.5 25.0 26.1 15.1 23.9 18.0 24.7 17.5 16.6 13.5 10.3 19.7 16.3 17.0 18.8 13.2 17.4 20.1 20.1 14.0 23.7 28.7 20.2 20.6 10.8 44.6 37.1 16.8 33.2 44.0 27.6 22.6 16.4 29.6 14.4 19.8 22.1 14.2 23.9 19.5 15.6 14.0 13.5 14.8 17.9 12.6 15.0 11.3 10.8 23.9 17.3 10.6 14.7 17.6 11.0 12.6 16.4 14.5 29.5 12.4 11.0 11.9 16.8 19.7 12.7 DARS ENSG00000115866 "Aspartyl-tRNA synthetase" P14868 2 135906677-135986100 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020451, HPA029804, HPA029805" Enhanced Enhanced Cytosol 160000 Cytosol "HPA020451: AB_1847479, HPA029804: AB_10599178, HPA029805: AB_10601994" "unprognostic (6.13e-2)" "unprognostic (8.16e-3)" "unprognostic (5.54e-2)" "unprognostic (5.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.91e-2)" "prognostic unfavourable (2.39e-6)" "unprognostic (2.98e-3)" "prognostic unfavourable (7.57e-4)" "unprognostic (6.00e-3)" "prognostic unfavourable (6.54e-4)" "unprognostic (2.78e-1)" "prognostic unfavourable (1.24e-5)" "unprognostic (1.04e-1)" "unprognostic (9.12e-2)" "unprognostic (3.94e-3)" "unprognostic (2.00e-1)" 30.3 29.7 35.0 27.6 35.5 19.7 34.9 18.0 28.3 27.6 25.4 25.6 26.9 14.8 30.1 26.7 44.4 26.9 19.6 29.8 29.0 28.8 34.6 35.5 19.7 32.3 32.1 25.6 34.0 27.0 26.4 24.5 31.7 23.8 31.0 20.3 20.6 26.6 28.3 45.1 30.6 21.4 42.4 33.8 29.8 23.6 12.8 25.0 42.0 33.0 33.1 36.7 45.3 30.2 48.6 30.5 11.2 18.8 36.6 42.7 30.6 47.1 19.4 16.6 17.5 18.5 23.2 38.0 23.6 26.5 25.9 25.4 41.8 20.6 55.1 37.0 19.4 27.2 25.4 30.6 47.1 25.2 22.7 33.5 19.2 43.4 23.9 44.8 22.3 22.3 24.7 28.9 26.1 14.2 35.9 17.6 21.4 22.2 34.3 38.6 19.5 18.5 42.0 36.1 38.5 31.1 18.4 11.8 22.5 18.1 16.4 18.4 18.0 32.0 10.7 22.7 22.7 16.7 23.4 48.5 26.4 59.3 35.7 34.2 14.0 6.0 18.8 11.2 27.5 18.3 41.2 48.6 41.3 36.0 30.5 43.8 42.7 37.0 7.3 36.6 14.0 29.2 36.9 30.6 35.0 35.5 18.0 23.8 29.0 28.8 32.1 25.6 23.8 25.0 DARS2 FLJ10514 ENSG00000117593 "Aspartyl-tRNA synthetase 2, mitochondrial" Q6PI48 1 173824503-173858546 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026506, HPA026528" Enhanced Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA026506: AB_1847482, HPA026528: AB_1847483" "unprognostic (3.14e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-3)" "unprognostic (4.10e-3)" "unprognostic (2.20e-1)" "unprognostic (1.42e-1)" "unprognostic (6.17e-2)" "unprognostic (1.15e-1)" "prognostic favourable (1.74e-4)" "unprognostic (3.30e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (4.73e-3)" 17.0 22.2 6.3 10.1 8.1 5.4 9.0 7.5 8.6 7.8 15.1 6.7 8.3 11.7 10.4 6.1 13.4 6.4 5.9 11.2 5.5 6.0 21.9 14.8 8.2 11.0 6.4 4.2 9.5 14.9 18.1 15.3 10.9 10.0 8.5 16.6 10.2 10.2 6.2 10.6 6.0 16.1 6.2 9.0 11.4 11.3 8.4 6.9 26.1 12.2 6.3 12.5 9.7 8.1 9.3 9.0 4.8 10.7 5.0 9.3 5.2 29.2 19.6 12.2 7.6 9.3 13.3 15.6 12.9 10.7 18.7 14.3 18.3 26.4 15.9 17.7 10.3 30.1 33.7 21.8 25.6 18.1 16.5 13.7 9.8 12.8 9.1 11.6 12.5 9.6 10.0 18.9 19.3 18.6 27.7 12.5 15.5 8.1 14.7 6.5 23.6 17.6 17.4 15.6 29.2 17.0 9.8 16.0 14.7 14.2 31.6 20.3 33.1 15.3 8.2 9.6 15.2 13.2 20.6 9.8 24.8 18.4 5.6 12.9 20.7 4.4 7.0 4.8 6.6 10.7 9.3 9.3 7.2 5.8 9.0 7.3 7.7 4.8 0.7 5.0 7.4 3.7 5.1 5.2 6.3 8.1 7.5 8.6 5.5 6.0 6.4 4.2 10.0 6.9 DBH DBM ENSG00000123454 "Dopamine beta-hydroxylase" P09172 9 133636360-133659344 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Monooxygenase, Oxidoreductase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "adrenal gland: 86.6;brain: 36.2;liver: 35.6" "Cell line enriched" "Detected in single" 340 "SH-SY5Y: 201.2" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 45 "pons and medulla: 36.2" "Cell type enhanced" "Detected in single" "naive CD4 T-cell: 2.0" "Lineage enriched" "Detected in single" 21 "T-cells: 2.0" "Region enriched" "Detected in some" 6 "pons and medulla: 23.2" "Region enriched" "Detected in single" 37 "pons and medulla: 25.1" "HPA002130, HPA005960, HPA070789" Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" 2000000000 Vesicles "Endoplasmic reticulum" "HPA002130: AB_2666554, HPA005960: AB_1078628, HPA070789: AB_2686312" "unprognostic (1.93e-3)" "unprognostic (7.52e-3)" "unprognostic (8.53e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-3)" "unprognostic (3.38e-3)" "unprognostic (3.39e-3)" "unprognostic (3.97e-2)" "unprognostic (1.71e-1)" "unprognostic (8.99e-2)" "unprognostic (5.80e-2)" "unprognostic (7.69e-2)" "unprognostic (2.81e-7)" "unprognostic (9.31e-2)" "unprognostic (6.77e-2)" "unprognostic (1.49e-2)" "unprognostic (5.06e-3)" 0.7 86.6 0.1 0.3 0.1 0.0 0.0 0.1 0.8 0.3 0.0 1.9 0.7 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.5 35.6 0.3 0.6 0.0 0.0 0.1 1.3 0.0 0.6 0.4 36.2 0.8 0.0 1.0 0.2 5.9 0.0 0.0 0.2 0.0 1.4 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.2 201.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.8 0.0 0.1 0.0 0.0 36.2 0.0 DBT ENSG00000137992 "Dihydrolipoamide branched chain transacylase E2" P11182 1 100186919-100249834 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026481, HPA026485, HPA026533" Enhanced Supported Mitochondria Mitochondria "HPA026481: AB_1847504, HPA026485: AB_1847505, HPA026533: AB_1847506" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" "unprognostic (3.67e-2)" "unprognostic (5.29e-2)" "unprognostic (1.92e-2)" "unprognostic (1.63e-1)" "unprognostic (3.88e-2)" "unprognostic (1.65e-2)" "unprognostic (6.01e-2)" "unprognostic (1.21e-1)" "unprognostic (2.37e-2)" "unprognostic (2.90e-1)" "prognostic favourable (8.79e-12)" "unprognostic (1.63e-1)" "unprognostic (3.77e-1)" "unprognostic (9.67e-2)" "unprognostic (9.92e-2)" 8.6 14.1 8.3 5.0 13.6 3.9 8.7 8.0 11.8 8.5 7.8 7.9 13.6 6.6 9.8 6.6 13.6 8.6 5.2 18.1 8.6 7.3 22.2 29.1 8.0 5.3 10.2 8.2 9.1 13.7 10.2 12.3 7.3 9.4 12.0 7.6 5.2 11.3 8.3 15.7 8.1 5.8 11.2 8.6 6.0 12.6 5.7 8.2 9.6 13.0 8.7 6.3 12.8 7.7 4.4 2.6 3.3 3.1 4.0 5.0 2.1 11.5 5.7 5.2 10.6 11.6 10.1 12.2 7.9 6.4 7.1 8.6 11.8 4.4 10.5 11.6 4.7 10.4 11.6 8.4 8.9 11.1 6.7 7.6 10.9 5.8 9.9 10.0 3.6 9.8 9.3 5.8 9.1 6.6 12.2 11.5 5.6 2.6 8.3 3.2 11.0 11.4 8.1 19.2 7.9 7.8 10.5 9.2 5.7 17.5 15.6 13.2 12.3 6.2 7.6 7.0 4.7 8.9 7.1 8.1 8.2 5.4 8.3 6.2 3.1 3.3 2.2 1.8 4.9 3.1 5.0 4.4 4.4 4.2 2.2 4.1 4.5 4.2 2.1 4.0 2.7 2.6 3.4 2.1 8.3 13.6 8.0 11.8 8.6 7.3 10.2 8.2 9.4 8.2 DCAF1 "KIAA0800, MGC102804, VPRBP" ENSG00000145041 "DDB1 and CUL4 associated factor 1" Q9Y4B6 3 51395867-51500002 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036142, HPA052445, HPA053203" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "HPA036142: AB_10669666, HPA052445: , HPA053203: " "unprognostic (7.51e-2)" "unprognostic (3.19e-1)" "unprognostic (3.71e-3)" "unprognostic (1.26e-1)" "unprognostic (5.15e-2)" "unprognostic (9.75e-2)" "unprognostic (2.58e-2)" "unprognostic (1.24e-1)" "unprognostic (8.75e-2)" "unprognostic (2.15e-1)" "unprognostic (2.89e-2)" "unprognostic (2.21e-2)" "prognostic favourable (7.45e-5)" "unprognostic (5.49e-2)" "unprognostic (5.00e-1)" "unprognostic (6.81e-2)" "unprognostic (1.64e-1)" 13.3 12.5 11.5 16.3 12.3 12.9 12.2 17.9 12.5 9.6 10.3 11.0 12.5 7.6 13.1 10.1 11.3 9.2 8.4 8.8 9.6 6.8 11.0 11.1 10.9 13.0 11.1 9.1 11.9 11.1 24.8 12.9 15.4 10.3 10.1 10.9 8.6 12.5 11.8 28.1 14.1 11.8 10.4 9.1 11.9 10.7 50.7 10.9 18.5 14.2 7.6 16.7 12.5 16.5 7.3 6.4 3.3 6.0 7.3 10.7 6.2 10.7 13.2 12.9 11.6 11.6 9.3 12.2 12.1 9.1 13.1 12.9 14.4 10.5 26.2 6.7 9.5 9.5 24.2 10.8 17.0 18.2 12.0 22.4 18.1 12.4 8.5 29.2 16.3 6.1 12.6 16.9 12.4 10.1 13.1 17.1 10.2 10.9 22.3 11.9 13.5 14.6 9.5 13.8 17.3 10.2 16.8 6.7 11.9 13.3 12.4 7.3 8.4 12.4 12.6 10.8 14.5 17.7 18.5 11.6 15.7 27.0 12.5 20.1 8.8 3.2 4.0 3.3 9.4 4.5 10.7 7.1 8.1 8.0 6.4 7.3 8.9 7.3 1.0 7.3 6.0 5.2 8.7 6.2 11.5 12.3 17.9 12.5 9.6 6.8 11.1 9.1 10.3 10.9 DCK ENSG00000156136 "Deoxycytidine kinase" P27707 4 70992538-71030914 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 80.9" "Cell line enhanced" "Detected in all" "Daudi: 59.7;U-698: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059609, HPA062773" Enhanced Supported Nucleoplasm Nucleoplasm "HPA059609: , HPA062773: " "unprognostic (9.16e-2)" "unprognostic (2.44e-1)" "unprognostic (5.24e-3)" "unprognostic (4.77e-2)" "unprognostic (3.95e-1)" "unprognostic (6.45e-2)" "prognostic unfavourable (6.90e-7)" "unprognostic (3.04e-2)" "unprognostic (7.19e-2)" "unprognostic (8.28e-2)" "unprognostic (4.51e-1)" "unprognostic (1.33e-1)" "unprognostic (3.37e-2)" "unprognostic (4.47e-2)" "unprognostic (6.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.27e-2)" 8.0 8.3 11.9 30.9 16.8 17.2 6.9 11.4 14.8 5.6 8.6 10.4 2.6 7.6 7.5 4.4 8.8 5.5 6.1 5.5 12.3 13.1 5.8 4.8 9.7 42.8 11.7 10.3 6.0 5.0 3.6 4.2 7.9 11.1 5.9 10.4 6.4 6.3 4.0 6.8 7.9 12.4 7.5 17.6 17.5 8.2 5.6 8.6 80.9 8.3 3.8 39.9 9.5 6.5 27.9 34.2 17.5 12.7 18.5 24.9 25.1 6.6 4.4 9.7 5.7 3.0 5.3 5.6 17.2 6.4 13.6 11.4 2.9 14.5 59.7 7.4 7.1 3.9 8.6 5.4 18.4 12.6 5.3 12.3 5.1 4.5 3.1 24.6 15.9 2.7 6.6 8.3 5.0 7.7 4.9 22.7 15.5 3.8 30.4 9.7 4.7 5.4 25.8 19.7 4.7 6.8 4.6 8.6 9.2 6.4 12.7 7.5 5.7 12.9 6.2 15.4 11.6 12.9 9.2 8.6 5.6 48.4 10.7 15.4 11.4 13.1 10.7 17.5 16.2 12.7 20.3 27.9 21.8 20.0 14.3 26.4 23.4 23.5 5.4 18.5 12.1 34.2 24.9 25.1 11.9 16.8 11.4 14.8 12.3 13.1 11.7 10.3 11.1 8.6 DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131306 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 76.5" "Cell line enhanced" "Detected in some" "ASC diff: 17.3;ASC TERT1: 16.4;fHDF/TERT166: 13.3;HAP1: 10.3;HSkMC: 15.1;NTERA-2: 21.4" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol 11000 Nucleoplasm Cytosol "CAB012405: , HPA015040: , HPA015655: " "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.72e-2)" "unprognostic (2.85e-1)" "prognostic unfavourable (4.42e-4)" "unprognostic (1.93e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-4)" 13.9 3.3 14.3 4.2 25.0 1.1 8.6 8.6 76.5 12.2 3.5 8.6 0.5 2.0 6.4 5.8 5.8 3.3 7.1 5.8 21.9 21.9 1.9 1.2 3.0 4.3 11.9 22.5 6.4 2.1 1.5 7.4 1.1 13.9 4.7 4.4 0.5 2.5 4.7 1.9 4.7 2.7 17.0 10.4 4.6 2.5 2.2 8.5 0.0 2.1 1.4 2.9 5.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.0 17.3 16.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 13.3 0.0 10.3 0.2 0.0 0.0 0.6 0.0 0.4 0.0 0.6 0.0 0.0 15.1 7.5 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 21.4 0.2 0.0 1.2 0.0 0.6 0.0 4.3 2.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.5 4.4 0.7 0.1 0.0 0.0 1.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 25.0 8.6 45.8 21.9 21.9 11.9 22.5 13.9 8.5 DCLK2 "DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428" ENSG00000170390 "Doublecortin like kinase 2" Q8N568 4 150078274-150257457 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 60.5" "Cell line enhanced" "Detected in many" "AF22: 18.2;BJ hTERT+: 19.0;fHDF/TERT166: 8.3" "Cancer enriched" "Detected in many" 17 "glioma: 53.3" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 2.5;plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015770 Enhanced "HPA015770: AB_1847509" "unprognostic (7.37e-2)" "unprognostic (1.56e-3)" "unprognostic (9.30e-2)" "unprognostic (1.49e-2)" "unprognostic (4.06e-1)" "unprognostic (6.24e-3)" "unprognostic (1.90e-1)" "unprognostic (7.38e-3)" "unprognostic (2.18e-1)" "prognostic favourable (3.25e-4)" "prognostic favourable (2.48e-4)" "unprognostic (6.87e-2)" "unprognostic (3.93e-3)" "unprognostic (3.74e-3)" "unprognostic (4.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.45e-2)" 2.9 3.9 23.3 2.1 23.5 1.6 2.0 9.3 60.5 3.1 2.8 16.5 0.8 2.8 4.3 3.5 3.0 2.8 4.0 14.4 23.5 17.5 2.9 1.8 2.7 1.6 14.9 14.5 4.3 3.5 1.4 4.7 2.9 20.2 3.9 3.5 2.1 2.0 3.6 2.3 2.1 2.7 6.4 23.4 2.1 2.2 4.2 15.9 0.0 4.1 0.0 1.5 3.3 2.0 2.5 1.5 0.0 0.5 0.0 0.0 0.0 0.8 3.2 18.2 2.8 0.0 0.9 0.3 8.2 19.0 2.7 0.6 0.1 0.0 0.0 0.3 8.3 0.0 2.6 0.0 3.4 3.7 1.6 0.0 4.7 0.0 3.9 0.5 0.5 0.5 0.0 1.6 0.2 0.9 0.0 0.0 1.9 0.1 0.3 0.0 0.3 1.0 0.0 2.1 0.7 0.0 0.8 7.0 6.6 3.4 2.5 0.8 0.0 0.0 1.6 2.5 1.0 1.6 0.9 0.8 0.0 0.0 2.4 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 23.3 23.5 9.3 19.3 23.5 17.5 14.9 14.5 20.2 15.9 DCLK3 "DCAMKL3, DCDC3C, KIAA1765" ENSG00000163673 "Doublecortin like kinase 3" Q9C098 3 36712422-36764349 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 10.0;testis: 8.0" "Cell line enhanced" "Detected in some" "NTERA-2: 3.3;SCLC-21H: 3.2;SH-SY5Y: 2.6;U-2 OS: 1.8;U-2197: 2.5" "Cancer enhanced" "Detected in single" "testis cancer: 1.2" "Region enhanced" "Detected in many" "basal ganglia: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040685 Approved "HPA040685: " "unprognostic (9.09e-3)" "unprognostic (1.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.66e-2)" "unprognostic (2.41e-1)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.96e-2)" "unprognostic (1.86e-2)" "unprognostic (2.05e-1)" "unprognostic (7.07e-2)" "unprognostic (6.11e-5)" "unprognostic (7.94e-3)" "unprognostic (5.80e-2)" "unprognostic (3.25e-3)" "unprognostic (1.36e-2)" 1.1 0.4 2.6 1.4 10.0 0.3 0.1 0.1 2.3 0.5 0.2 0.3 0.0 0.5 0.3 0.1 0.1 0.2 0.6 0.9 1.4 0.9 0.0 0.1 0.3 0.2 0.6 0.0 0.0 0.2 0.4 1.8 1.1 0.4 0.3 0.3 1.3 1.7 0.2 2.7 0.4 0.4 0.9 0.7 0.1 0.0 8.0 3.2 0.0 0.9 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.2 3.2 2.6 0.1 0.3 0.0 0.0 0.4 0.3 0.0 1.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 10.0 0.1 2.3 1.4 0.9 0.6 0.0 0.4 3.2 DCP2 NUDT20 ENSG00000172795 "Decapping mRNA 2" Q8IU60 5 112976702-113020970 "Enzymes, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 52.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011677, HPA057676" Approved Approved "Nucleoplasm,Cell Junctions,Cytoplasmic bodies" "Nucleoplasm, Cytoplasmic bodies" "Cell Junctions" "CAB011677: AB_731858, HPA057676: " "unprognostic (2.76e-1)" "unprognostic (3.27e-1)" "unprognostic (2.79e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-1)" "unprognostic (3.86e-3)" "prognostic unfavourable (4.84e-4)" "unprognostic (1.87e-1)" "unprognostic (3.64e-2)" "unprognostic (6.26e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-2)" "prognostic unfavourable (2.66e-5)" "unprognostic (8.39e-2)" "unprognostic (2.84e-1)" "unprognostic (3.25e-2)" "unprognostic (5.75e-2)" 8.0 7.5 8.1 16.3 9.5 22.9 15.0 16.8 10.9 9.1 6.6 6.4 6.6 6.3 10.5 6.8 7.4 8.0 6.5 6.1 8.1 8.9 8.1 8.1 13.2 19.8 6.9 6.1 12.8 6.2 7.0 12.2 40.2 8.3 8.1 7.3 6.5 9.6 8.6 8.3 9.8 8.7 7.3 7.4 19.9 6.7 6.8 6.5 52.9 7.0 4.1 20.0 8.7 9.1 5.1 6.5 16.3 8.3 3.9 5.9 3.2 3.6 3.1 14.1 11.3 2.8 3.1 22.8 3.3 2.7 4.2 6.1 14.6 7.8 19.1 5.3 1.9 4.5 16.2 4.5 5.1 5.1 7.1 17.9 2.7 5.8 3.2 10.9 9.3 2.9 3.1 5.1 5.1 7.1 13.2 7.5 3.8 4.6 16.0 11.6 12.2 1.9 15.7 13.4 7.1 6.5 9.3 3.3 7.0 4.6 5.2 6.7 15.4 14.6 4.6 4.7 8.4 2.4 5.0 5.1 11.2 14.6 2.7 15.3 3.6 12.2 7.2 5.5 4.0 7.1 5.5 5.1 4.9 4.2 6.5 3.6 4.6 4.7 16.3 3.9 8.3 3.5 5.9 3.2 8.1 9.5 16.8 10.9 8.1 8.9 6.9 6.1 8.3 6.5 DCPS "HINT-5, HSL1, HSPC015" ENSG00000110063 "Decapping enzyme, scavenger" Q96C86 11 126303752-126345749 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" Hydrolase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039632, HPA058597" Supported Supported Nucleoplasm,Cytosol 1400000 Nucleoplasm Cytosol "HPA039632: AB_10794200, HPA058597: " "unprognostic (1.45e-1)" "unprognostic (5.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.55e-2)" "unprognostic (5.22e-2)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (5.57e-2)" "unprognostic (1.91e-2)" "unprognostic (4.83e-2)" "unprognostic (5.00e-2)" "unprognostic (5.25e-2)" "unprognostic (2.24e-2)" "unprognostic (8.04e-2)" "unprognostic (7.67e-2)" "unprognostic (3.40e-2)" 11.1 13.1 6.8 14.4 8.2 13.5 9.2 8.5 14.5 12.1 10.6 6.8 8.0 7.8 12.4 9.6 14.4 9.9 13.9 10.9 5.5 6.1 13.3 39.6 9.9 18.5 6.3 5.8 11.8 17.2 7.0 9.5 14.1 6.8 12.7 11.7 13.3 17.4 9.4 21.8 11.3 9.7 11.3 7.1 21.9 9.6 13.4 6.5 22.0 12.7 18.5 22.1 15.1 9.8 13.2 39.5 3.2 14.3 7.8 14.6 7.1 10.5 6.6 8.3 13.7 6.4 8.6 6.9 5.6 8.3 8.6 8.7 12.5 21.7 14.4 21.2 8.9 12.4 11.7 17.6 5.7 27.2 6.3 21.1 7.6 10.8 14.0 22.6 19.1 8.7 11.1 10.9 14.9 11.5 8.5 24.7 9.4 15.2 14.4 25.9 5.8 22.7 10.0 12.1 27.4 8.3 11.8 10.7 8.2 17.0 13.9 10.3 23.6 14.2 7.3 13.5 6.3 6.4 10.5 9.9 9.2 14.9 3.9 39.2 33.8 1.7 9.2 3.2 8.8 14.3 8.2 13.2 8.5 9.0 15.4 9.0 6.0 6.8 0.5 7.8 12.6 39.5 14.6 7.1 6.8 8.2 8.5 14.5 5.5 6.1 6.3 5.8 6.8 6.5 DCST1 FLJ32785 ENSG00000163357 "DC-STAMP domain containing 1" Q5T197 1 155033824-155050930 "Enzymes, Predicted membrane proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "retina: 18.2;skin 1: 6.8;testis: 10.7" "Cell line enhanced" "Detected in some" "HaCaT: 4.8;HeLa: 4.0;RPMI-8226: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA060314 Uncertain "HPA060314: " "unprognostic (1.44e-1)" "unprognostic (7.66e-2)" "unprognostic (3.77e-2)" "unprognostic (1.05e-4)" "unprognostic (3.58e-2)" "unprognostic (8.75e-4)" "unprognostic (1.46e-2)" "unprognostic (2.66e-1)" "unprognostic (6.01e-3)" "unprognostic (2.22e-1)" "unprognostic (6.62e-2)" "unprognostic (1.89e-2)" "unprognostic (8.33e-15)" "unprognostic (7.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.38e-1)" "unprognostic (1.23e-1)" 0.2 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.2 0.1 0.1 0.1 1.7 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.0 18.2 0.7 0.1 0.1 6.8 1.6 0.1 0.1 0.2 0.4 10.7 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.8 0.8 0.9 1.2 0.0 1.0 0.1 1.5 0.7 2.7 1.5 0.1 0.0 1.0 0.5 0.0 0.0 0.0 0.7 3.2 1.5 0.5 0.0 4.8 0.0 0.0 0.0 1.2 0.4 0.4 4.0 0.3 0.0 1.1 0.6 0.0 0.2 0.0 0.0 0.0 1.1 2.3 0.0 1.0 0.0 0.3 0.2 2.2 0.0 1.1 5.4 0.0 0.8 0.9 1.8 0.6 1.8 0.2 3.4 0.1 0.0 0.3 0.2 0.8 0.4 0.9 0.8 0.3 0.7 1.6 0.0 0.0 0.2 0.9 0.1 0.0 0.0 0.8 0.4 0.2 0.3 0.0 1.0 0.2 0.2 0.0 1.2 0.8 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436808-94479682 "Enzymes, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 58 "retina: 151.5;skin 1: 54.2" "Cell line enriched" "Detected in single" 259 "SK-MEL-30: 75.0" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.2 0.2 0.5 0.1 1.5 0.1 1.7 0.2 0.6 0.2 0.1 0.3 0.1 0.0 0.2 0.5 0.1 0.8 0.1 0.1 0.4 0.5 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.1 1.4 0.1 0.3 0.2 0.0 151.5 1.4 0.2 0.2 54.2 0.2 0.1 0.8 0.1 0.0 0.3 0.4 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 75.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.5 0.2 0.6 0.4 0.5 0.3 0.1 0.3 0.4 DCTD ENSG00000129187 "DCMP deaminase" P32321 4 182890060-182917936 "Enzymes, Predicted intracellular proteins" "Nucleotide biosynthesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035894 Approved Approved Nucleoplasm,Cytosol 13000 "Nucleoplasm, Cytosol" "HPA035894: AB_10673488" "unprognostic (1.26e-1)" "unprognostic (9.80e-3)" "unprognostic (3.15e-2)" "unprognostic (3.78e-3)" "unprognostic (3.13e-3)" "unprognostic (2.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.59e-3)" "unprognostic (2.62e-2)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.20e-1)" "prognostic favourable (1.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.59e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-1)" 24.8 46.2 24.7 19.9 23.8 12.9 27.3 11.6 28.3 27.1 20.4 17.3 22.6 16.4 26.0 20.1 30.9 25.9 40.9 25.8 22.5 22.2 25.7 47.6 25.8 29.4 21.1 20.3 35.9 51.7 28.3 25.3 18.9 21.3 23.7 21.5 30.0 26.4 22.8 24.8 19.4 19.1 27.4 25.6 24.9 27.2 11.8 16.7 15.0 52.9 21.3 26.0 24.5 25.1 31.9 24.8 23.7 25.7 30.8 36.8 22.7 22.4 20.7 21.2 19.5 32.0 43.7 27.7 43.3 38.7 31.1 19.3 21.0 43.7 7.8 10.7 42.2 11.2 15.4 27.0 28.6 37.8 11.7 36.1 12.0 25.0 34.3 35.1 22.6 36.3 28.9 27.3 28.5 26.6 35.8 78.2 41.3 16.3 22.7 21.5 16.8 18.1 24.8 15.1 15.1 25.0 27.0 20.9 13.0 20.5 17.7 20.2 13.6 18.4 30.9 25.9 19.9 12.5 33.0 30.1 16.2 10.0 28.6 23.0 30.4 23.7 22.0 19.7 29.2 25.7 36.8 31.9 25.6 29.7 24.8 21.7 25.5 26.7 1.6 30.8 24.9 19.1 21.9 22.7 24.7 23.8 11.6 28.3 22.5 22.2 21.1 20.3 21.3 16.7 DCTPP1 "CDA03, MGC5627, RS21C6, XTP3TPA" ENSG00000179958 "DCTP pyrophosphatase 1" Q9H773 16 30423619-30430075 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002832 Uncertain Approved Nucleoplasm,Cytosol 270000 "Nucleoplasm, Cytosol" "HPA002832: AB_1080615" "prognostic unfavourable (1.64e-5)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (4.09e-2)" "prognostic unfavourable (6.28e-4)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (4.35e-2)" "unprognostic (2.43e-2)" "unprognostic (3.65e-2)" "prognostic favourable (9.71e-9)" "unprognostic (1.10e-3)" "unprognostic (8.78e-3)" "unprognostic (1.10e-2)" "unprognostic (2.53e-1)" 15.3 15.8 14.8 25.0 13.2 12.5 20.7 15.5 19.2 12.1 37.4 10.3 11.3 20.7 14.1 14.4 19.7 18.9 28.1 23.3 12.1 12.6 27.0 25.3 11.2 27.6 13.3 16.6 16.6 25.2 16.4 7.7 16.3 11.4 15.4 40.3 10.6 20.5 21.1 28.3 16.1 22.9 13.9 11.3 22.5 16.4 9.9 7.8 21.3 22.6 26.0 25.0 13.2 13.0 47.3 30.9 19.0 24.5 23.1 26.2 25.3 26.3 32.4 14.8 19.0 4.2 5.7 13.7 12.7 7.6 19.2 19.6 24.3 22.5 35.7 26.7 7.9 20.7 30.6 24.9 24.0 18.8 48.3 20.8 14.9 31.6 5.4 37.1 32.4 6.5 14.2 21.4 12.3 19.7 26.1 12.6 13.6 46.0 44.1 41.6 19.5 26.2 62.6 16.4 46.5 22.2 17.2 31.5 17.8 8.4 30.2 11.9 26.1 16.0 9.9 14.9 13.3 19.1 22.8 8.3 24.7 45.5 9.8 30.8 17.3 19.0 12.4 11.7 18.8 22.1 26.2 47.3 24.2 21.3 28.7 40.2 21.8 21.0 1.5 23.1 24.5 30.9 24.1 25.3 14.8 13.2 15.5 19.2 12.1 12.6 13.3 16.6 11.4 7.8 DCXR "DCR, KIDCR, SDR20C1" ENSG00000169738 "Dicarbonyl and L-xylulose reductase" Q7Z4W1 17 82035136-82037732 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Xylose metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 293.8" "Cell line enhanced" "Detected in all" "Hep G2: 64.9;MCF7: 79.8" "Cancer enhanced" "Detected in all" "liver cancer: 305.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023371, HPA023863" Enhanced Uncertain Nucleoli,Microtubules 2700000 "Nucleoli, Microtubules" "HPA023371: AB_1847530, HPA023863: AB_1847531" "unprognostic (3.33e-2)" "unprognostic (1.67e-3)" "unprognostic (3.75e-1)" "unprognostic (1.16e-2)" "unprognostic (1.19e-1)" "unprognostic (8.43e-2)" "unprognostic (4.54e-3)" "unprognostic (1.86e-2)" "unprognostic (3.05e-1)" "unprognostic (2.56e-2)" "prognostic favourable (4.70e-4)" "unprognostic (1.72e-1)" "prognostic favourable (2.13e-4)" "unprognostic (1.81e-1)" "unprognostic (1.36e-1)" "unprognostic (2.64e-1)" "unprognostic (1.10e-2)" 12.7 6.1 12.8 4.3 12.1 5.7 12.2 9.0 15.1 9.9 9.5 8.4 18.1 7.8 4.4 62.7 11.7 6.1 4.8 11.8 9.8 9.7 50.8 293.8 10.5 5.3 14.4 7.3 8.1 13.0 6.7 7.2 9.0 13.4 22.3 5.4 7.8 19.3 14.0 22.5 8.6 6.8 3.6 8.4 4.4 14.9 8.7 9.7 8.3 15.6 12.6 9.1 7.5 6.4 32.8 52.7 25.3 33.1 35.2 43.7 35.8 8.9 12.3 5.7 10.3 23.0 5.8 15.2 4.6 6.0 12.7 8.7 21.8 3.9 18.5 9.0 6.4 10.6 10.4 9.2 4.4 3.9 26.7 17.7 9.2 64.9 24.7 13.6 21.8 8.4 11.5 4.0 14.6 7.1 20.2 13.5 6.7 79.8 11.4 32.7 6.6 13.1 10.5 7.7 24.2 9.4 12.7 15.9 9.4 6.4 55.0 8.0 41.2 13.5 3.6 6.7 8.4 9.0 8.6 13.9 10.2 8.7 5.7 15.0 4.9 13.9 33.1 25.3 24.7 30.6 23.6 28.6 30.8 23.6 52.7 32.8 43.7 31.9 16.5 35.2 28.0 42.5 33.1 35.8 12.8 12.1 9.0 15.1 9.8 9.7 14.4 7.3 13.4 9.7 DDAH1 DDAH ENSG00000153904 "Dimethylarginine dimethylaminohydrolase 1" O94760 1 85318481-85578363 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 61.6" "Cell line enhanced" "Detected in many" "SH-SY5Y: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006308 Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" 140000 "Plasma membrane, Cytosol" Nucleoli "HPA006308: AB_1847532" "unprognostic (1.44e-2)" "unprognostic (2.43e-1)" "prognostic favourable (5.99e-4)" "unprognostic (6.82e-2)" "unprognostic (1.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.02e-2)" "unprognostic (3.62e-2)" "unprognostic (1.56e-1)" "prognostic favourable (5.21e-6)" "unprognostic (5.37e-2)" "unprognostic (9.06e-2)" "unprognostic (5.81e-2)" "unprognostic (1.56e-2)" 4.3 14.3 43.9 5.8 44.9 0.7 6.6 14.4 37.2 7.7 22.1 20.7 4.3 21.1 6.0 33.8 4.9 18.4 12.2 6.4 29.5 24.1 61.6 39.9 11.8 1.1 24.9 37.0 3.4 13.8 13.0 7.2 3.1 13.8 13.1 21.4 4.1 8.5 6.2 13.8 2.8 19.9 7.4 8.1 4.1 15.6 9.3 11.0 0.0 14.1 1.0 1.2 6.0 3.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 18.7 2.3 6.6 1.2 11.1 9.4 0.8 22.1 13.4 7.9 8.4 26.6 5.0 0.0 9.2 25.0 5.4 23.9 4.6 10.1 0.0 9.2 0.0 6.3 9.2 4.0 17.0 1.0 7.8 0.4 6.6 4.2 12.5 0.0 1.9 20.2 1.5 0.9 0.0 7.9 6.9 0.0 15.5 0.2 33.7 14.0 18.7 36.3 2.9 16.8 2.7 9.1 1.3 24.4 6.9 5.6 1.7 15.4 0.0 0.0 0.0 0.3 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 43.9 44.9 14.4 37.2 29.5 24.1 24.9 37.0 13.8 11.0 DDAH2 G6A ENSG00000213722 "Dimethylarginine dimethylaminohydrolase 2" O95865 6 31727038-31730617 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 10.6;ASC TERT1: 13.2;EFO-21: 16.9;fHDF/TERT166: 10.5;SK-MEL-30: 10.6;U-2 OS: 12.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012509 Uncertain Supported "Centriolar satellite,Cytosol" 1800000 Cytosol "Centriolar satellite" "HPA012509: AB_1847533" "unprognostic (2.29e-2)" "unprognostic (1.38e-1)" "unprognostic (4.49e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.62e-1)" "unprognostic (8.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (9.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.24e-2)" "unprognostic (2.72e-2)" 24.3 7.8 12.5 11.1 10.3 5.5 22.7 3.1 7.8 32.1 17.0 7.9 12.9 2.6 34.6 22.0 18.4 18.1 26.7 20.7 11.8 10.8 16.9 12.9 37.4 16.5 10.6 6.6 22.5 4.3 3.0 6.2 13.7 13.1 19.8 5.4 13.0 18.1 13.2 6.8 15.1 22.3 27.1 18.9 21.4 11.4 7.3 9.9 14.1 35.4 17.1 8.9 16.3 23.4 2.9 5.5 8.0 2.7 2.3 0.5 0.3 0.4 6.6 0.2 1.4 10.6 13.2 0.7 0.6 0.3 0.4 0.1 4.3 0.7 0.2 16.9 10.5 0.8 0.0 6.2 0.0 0.1 8.9 0.5 0.5 0.1 0.3 0.9 0.0 8.5 0.1 0.8 0.1 0.1 0.2 2.2 0.0 3.6 0.5 2.5 0.1 0.2 0.3 0.5 0.0 7.5 0.7 0.4 0.9 0.3 0.0 10.6 0.7 0.9 1.1 0.8 12.6 0.2 0.1 2.7 9.2 2.5 7.3 1.5 0.2 8.0 0.8 7.7 0.5 2.6 0.3 2.9 0.2 0.3 1.5 2.5 0.1 0.1 1.3 2.3 2.7 5.5 0.4 0.3 12.5 10.3 3.1 7.8 11.8 10.8 10.6 6.6 13.1 9.9 DDC AADC ENSG00000132437 "Dopa decarboxylase" P20711 7 50458436-50565457 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 90.1;kidney: 68.1" "Group enriched" "Detected in some" 8 "CACO-2: 17.4;Hep G2: 15.3;SCLC-21H: 44.0;SH-SY5Y: 45.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "midbrain: 7.9;pons and medulla: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "midbrain: 90.4;pons and medulla: 40.7" HPA017742 Enhanced Approved "Actin filaments" 380000 "Actin filaments" "HPA017742: AB_1847832" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (2.57e-2)" "unprognostic (3.49e-5)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.15e-2)" "unprognostic (4.69e-2)" "unprognostic (5.44e-2)" "unprognostic (9.36e-3)" "unprognostic (5.24e-2)" "unprognostic (1.76e-3)" "unprognostic (1.60e-1)" "unprognostic (3.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.16e-1)" 0.3 10.9 0.3 3.0 0.7 0.0 0.3 0.3 0.4 0.3 36.7 0.4 0.3 33.5 0.3 1.8 0.3 0.0 0.7 0.3 0.3 1.3 68.1 11.7 0.7 0.3 7.9 0.3 0.4 9.8 0.0 0.3 0.3 3.4 0.4 8.1 0.4 0.3 0.3 0.3 0.1 90.1 0.3 0.3 0.3 4.3 0.6 0.5 0.3 0.3 0.4 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 44.0 45.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.3 0.4 0.3 1.3 7.9 0.3 3.4 0.5 DDO ENSG00000203797 "D-aspartate oxidase" Q99489 6 110391771-110415562 "Enzymes, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "RPMI-8226: 14.5;U-937: 16.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 4.9;myeloid DC: 7.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037525, HPA037526" Enhanced Enhanced Cytosol Cytosol "HPA037525: AB_2675523, HPA037526: AB_10672352" "unprognostic (1.37e-1)" "unprognostic (1.54e-1)" "unprognostic (6.51e-2)" "unprognostic (1.30e-2)" "unprognostic (2.00e-1)" "unprognostic (3.28e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.91e-1)" "unprognostic (6.97e-2)" "unprognostic (1.43e-1)" "prognostic favourable (8.69e-5)" "unprognostic (3.51e-4)" "unprognostic (3.36e-3)" "unprognostic (1.27e-3)" "unprognostic (9.06e-2)" 3.7 11.0 5.2 1.1 12.1 1.6 3.3 1.9 5.5 2.7 3.6 10.8 4.9 8.6 2.7 5.4 1.2 6.1 3.9 21.0 6.9 3.4 12.3 12.8 3.9 1.3 8.0 6.1 1.2 5.5 18.6 1.9 2.1 8.0 2.9 3.9 2.3 4.9 3.2 11.3 0.8 7.9 5.6 7.7 2.6 1.9 0.4 8.2 0.0 3.3 5.7 0.5 3.6 1.6 0.0 7.3 0.1 4.9 1.7 0.0 1.5 0.2 0.0 0.0 0.1 0.0 0.2 1.0 0.2 5.1 1.2 0.9 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 2.3 4.6 0.0 4.7 0.0 4.0 1.6 0.0 0.0 0.1 0.0 2.6 0.1 0.0 0.0 1.8 4.2 0.0 0.0 0.2 0.0 0.1 0.1 2.9 14.5 0.0 4.6 0.1 0.1 0.0 0.4 0.6 0.7 1.0 0.9 1.0 0.1 0.0 2.4 0.1 0.3 0.0 1.9 16.1 0.0 0.1 4.6 0.0 0.0 4.9 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.1 1.7 1.6 0.0 0.0 1.5 5.2 12.1 1.9 5.5 6.9 3.4 8.0 6.1 8.0 8.2 DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 31.2;HBEC3-KT: 24.0;RT4: 31.9;T-47d: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA057194" Approved Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" 2100000 "Nucleoplasm, Cell Junctions" "CAB010162: AB_2092090, CAB025656: , HPA057194: " "unprognostic (2.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.75e-3)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (4.41e-2)" "prognostic favourable (3.31e-10)" "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (5.49e-3)" "unprognostic (4.09e-2)" 6.7 11.3 23.5 7.9 36.2 2.2 12.5 6.8 42.2 9.7 25.2 57.4 17.6 16.8 7.7 10.5 30.5 31.7 18.9 8.7 27.8 20.8 19.8 3.5 13.2 3.1 55.7 19.8 11.3 20.9 28.2 14.6 13.3 34.7 17.7 14.9 4.0 28.3 20.5 9.1 41.3 32.1 3.1 43.2 5.1 52.2 5.1 37.0 8.7 20.9 10.5 7.6 16.3 16.6 1.8 0.4 0.0 0.2 0.0 1.8 0.9 19.3 6.4 9.1 1.9 0.6 0.8 5.6 0.5 0.1 0.2 0.0 8.6 10.3 0.1 10.8 1.7 31.2 1.9 24.0 0.1 10.7 3.4 0.0 5.8 2.2 1.8 0.0 0.4 1.2 12.4 0.1 0.2 0.7 5.6 0.2 1.3 12.2 0.6 0.0 1.5 1.3 1.3 6.8 0.7 4.6 31.9 1.6 0.8 1.8 14.4 7.0 35.8 0.2 1.4 4.5 4.2 0.4 4.5 0.2 0.0 0.8 2.9 0.0 3.9 0.0 0.2 0.0 1.1 0.0 0.8 0.4 0.2 0.7 0.4 1.8 1.2 1.8 0.0 0.0 0.0 0.4 0.0 0.9 23.5 36.2 6.8 25.0 27.8 20.8 55.7 19.8 34.7 37.0 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787400 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 60.6;ASC TERT1: 59.9;BJ hTERT+: 44.3;fHDF/TERT166: 31.7;HSkMC: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 5 "T-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Supported "Plasma membrane,Actin filaments" 850000 "Plasma membrane, Actin filaments" "HPA070112: " "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavourable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 42.1 43.5 4.7 10.9 6.9 0.2 15.6 7.9 7.1 30.3 30.4 9.0 18.6 3.3 24.2 17.7 25.0 13.4 16.6 15.4 7.9 4.7 4.0 3.3 8.9 5.1 12.9 3.4 26.4 2.2 2.1 4.0 6.6 12.7 21.8 9.1 30.7 6.4 19.3 5.2 6.1 10.1 34.3 19.7 3.4 14.1 8.3 7.5 0.0 8.6 12.8 4.1 29.0 18.3 0.1 0.2 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.0 16.0 60.6 59.9 0.2 23.6 44.3 10.3 14.9 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.1 14.1 12.7 0.1 0.0 0.0 0.0 26.3 0.0 0.0 42.5 0.1 18.2 0.4 11.8 0.1 5.0 9.4 0.0 0.0 0.0 0.1 0.1 0.0 6.7 0.1 0.0 0.0 0.0 9.7 0.0 0.0 0.8 0.0 0.0 0.6 16.5 3.6 8.3 3.2 0.7 1.3 0.0 14.9 0.0 16.7 0.0 0.0 0.0 1.1 0.0 1.3 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 4.7 6.9 7.9 7.1 7.9 4.7 12.9 3.4 12.7 7.5 DDT DDCT ENSG00000099977 "D-dopachrome tautomerase" P30046 22 23971365-23980469 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Melanin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 52.8;liver: 58.4" "Cell line enhanced" "Detected in all" "HEK 293: 67.6" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA049871 Approved Approved Mitochondria Mitochondria "HPA049871: " "unprognostic (1.77e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (8.09e-2)" "unprognostic (4.00e-3)" "unprognostic (2.02e-3)" "unprognostic (6.58e-2)" "unprognostic (4.66e-2)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-3)" "unprognostic (1.12e-1)" "unprognostic (7.34e-2)" "unprognostic (3.30e-1)" "unprognostic (3.81e-1)" "unprognostic (2.61e-3)" 9.7 6.6 5.4 3.4 4.8 8.8 4.5 2.1 4.4 3.0 9.8 11.8 2.7 4.3 5.8 2.8 1.4 7.7 4.2 4.0 11.3 58.4 3.2 2.9 5.4 4.1 14.4 1.3 1.8 2.5 5.8 6.4 7.1 4.4 10.4 3.7 11.6 2.0 4.6 3.2 8.2 1.2 3.7 2.7 4.3 3.2 30.4 52.8 27.8 38.0 23.8 29.0 28.6 26.7 11.4 4.0 9.3 7.6 6.7 24.2 7.8 5.3 6.8 7.1 10.1 7.7 25.6 7.3 4.1 22.2 9.8 9.7 4.5 10.8 67.6 15.4 15.6 21.9 7.7 33.8 15.5 6.7 7.4 6.8 6.0 7.3 13.9 10.4 6.8 13.1 7.4 30.6 12.0 34.5 16.3 7.4 36.6 12.1 9.9 13.5 13.0 16.1 30.4 22.9 7.7 10.6 8.4 7.1 15.8 7.2 8.1 32.0 10.6 16.1 13.9 12.6 13.6 20.7 38.0 27.8 19.9 32.4 20.3 30.4 24.1 21.1 35.7 28.4 21.9 21.3 24.2 23.8 29.6 52.8 29.0 28.6 DDX1 DBP-RB ENSG00000079785 "DEAD-box helicase 1" Q92499 2 15591178-15631111 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, mRNA processing, Transcription, Transcription regulation, tRNA processing" "Activator, DNA-binding, Exonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012280, HPA034502, HPA034503" Enhanced Enhanced Nucleoplasm,Cytosol 46000 Nucleoplasm Cytosol "CAB012280: , HPA034502: AB_10794321, HPA034503: AB_10795025" "unprognostic (9.94e-2)" "unprognostic (2.95e-2)" "unprognostic (3.07e-2)" "unprognostic (8.36e-3)" "unprognostic (9.28e-3)" "unprognostic (1.56e-2)" "prognostic unfavourable (9.09e-9)" "unprognostic (2.55e-1)" "unprognostic (2.05e-1)" "unprognostic (4.81e-3)" "unprognostic (3.89e-2)" "unprognostic (2.03e-1)" "prognostic favourable (9.69e-4)" "unprognostic (3.80e-1)" "unprognostic (1.34e-1)" "unprognostic (4.94e-2)" "unprognostic (1.20e-3)" 23.8 28.2 29.3 17.6 35.0 17.1 30.1 35.3 37.2 25.1 24.5 15.0 20.5 21.0 24.3 25.6 27.7 21.0 15.8 47.6 34.7 25.3 35.8 35.2 17.8 16.0 24.5 36.9 23.6 27.6 42.1 41.2 28.1 35.1 22.2 28.1 14.8 23.9 24.5 67.5 24.5 25.9 31.0 21.0 17.1 24.1 19.2 23.0 23.0 29.6 24.8 21.5 26.1 19.8 18.7 22.8 19.2 25.1 23.0 26.6 19.9 19.1 29.4 41.8 31.2 36.3 31.9 48.2 40.3 33.8 39.7 33.4 46.9 19.8 49.7 19.6 46.4 29.2 57.1 38.6 42.0 21.1 37.1 54.5 39.3 59.1 27.3 44.5 25.7 24.7 26.7 33.0 31.8 35.7 55.5 16.4 39.1 26.8 24.3 33.6 53.8 24.8 29.4 63.3 36.0 45.4 38.6 33.7 42.2 27.5 29.0 36.6 20.2 18.9 28.8 33.3 34.5 20.9 45.4 21.5 37.3 67.1 30.0 35.7 31.0 19.2 20.0 11.5 20.2 25.1 21.3 18.7 23.4 23.4 22.8 18.0 26.6 23.6 3.1 23.0 23.2 19.5 21.6 19.9 29.3 35.0 35.3 37.2 34.7 25.3 24.5 36.9 35.1 23.0 DDX10 "Dbp4, HRH-J8" ENSG00000178105 "DEAD-box helicase 10" Q13206 11 108665025-108940930 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004691 Approved Approved Nucleoli Nucleoli "HPA004691: AB_1078629" "unprognostic (9.49e-2)" "unprognostic (9.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (7.97e-2)" "unprognostic (1.48e-2)" "prognostic unfavourable (2.52e-5)" "unprognostic (2.86e-2)" "unprognostic (1.23e-2)" "unprognostic (1.06e-1)" "prognostic unfavourable (5.75e-4)" "unprognostic (1.00e-1)" "prognostic favourable (2.14e-5)" "unprognostic (5.20e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-1)" "unprognostic (2.43e-3)" 14.0 11.9 17.3 15.0 20.3 10.4 15.5 20.5 18.3 14.3 12.2 8.1 11.7 8.8 18.4 12.8 12.6 16.8 8.8 12.1 13.5 11.5 19.6 12.5 10.6 13.1 12.2 16.3 18.6 18.0 16.7 22.2 12.9 13.1 12.4 13.3 7.9 10.6 14.7 13.6 14.8 9.1 16.8 13.3 15.0 11.3 25.1 12.6 13.8 13.4 8.8 14.2 14.3 18.8 11.6 8.4 1.4 6.7 9.4 11.3 4.3 7.2 7.1 6.8 9.5 6.7 5.5 7.1 7.8 4.2 9.5 9.4 20.3 10.7 24.7 14.8 6.0 8.2 19.4 9.5 13.7 9.4 8.7 16.8 4.2 7.6 12.0 17.1 8.0 4.9 7.5 10.8 13.5 8.6 23.5 2.7 9.3 4.7 14.3 14.4 8.8 10.9 12.2 11.1 23.1 5.8 6.3 12.6 6.7 11.0 9.7 4.1 11.7 6.0 9.1 10.0 10.2 9.5 10.6 4.2 7.3 57.2 3.4 20.6 10.1 1.4 5.0 1.0 8.6 6.7 11.3 10.4 7.5 10.1 8.4 11.6 8.1 7.8 0.7 9.4 6.4 8.2 6.3 4.3 17.3 20.3 20.5 18.3 13.5 11.5 12.2 16.3 13.1 12.6 DDX11 "CHL1, CHLR1, KRG2, WABS" ENSG00000013573 "DEAD/H-box helicase 11" Q96FC9 12 31073845-31104791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA065197 Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Centrosome" Nucleoplasm "Nucleoli fibrillar center, Centrosome" "HPA065197: " "unprognostic (6.10e-2)" "unprognostic (1.48e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.79e-3)" "prognostic unfavourable (2.40e-4)" "unprognostic (4.87e-2)" "unprognostic (3.89e-3)" "unprognostic (3.53e-1)" "unprognostic (5.66e-2)" "unprognostic (1.25e-1)" "prognostic unfavourable (5.23e-8)" "unprognostic (1.89e-2)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (8.03e-3)" 6.3 5.3 6.4 8.0 8.7 21.0 5.9 18.1 10.5 7.6 6.1 6.0 8.8 7.1 11.0 3.7 7.6 7.5 5.1 4.0 7.0 2.7 6.5 7.0 4.9 14.9 8.4 4.6 9.6 19.0 7.7 9.3 5.6 7.1 8.0 8.6 5.0 11.3 7.1 8.8 14.2 12.1 8.0 6.7 10.9 8.0 8.2 9.4 33.2 7.2 6.4 11.1 5.8 7.8 5.8 4.9 1.3 7.3 4.3 5.5 1.9 12.4 12.2 14.1 12.6 2.2 4.7 20.8 7.7 3.9 9.1 9.7 14.4 21.2 16.3 10.8 4.1 12.3 11.1 10.6 7.3 14.9 22.8 19.4 20.2 8.9 0.8 13.6 12.6 4.5 4.7 11.5 9.0 4.4 9.5 36.5 6.5 10.3 23.3 20.4 29.7 6.5 18.8 22.1 22.7 4.8 14.2 10.2 7.5 7.9 12.2 3.9 10.3 8.7 3.6 7.9 15.6 15.3 14.0 14.8 11.4 39.0 9.4 10.9 7.2 0.0 2.3 1.3 4.2 2.5 3.3 5.2 4.0 3.1 3.1 5.8 4.1 5.5 1.1 4.3 7.3 4.9 3.4 1.9 6.4 8.7 18.1 10.5 7.0 2.7 8.4 4.6 7.1 9.4 DDX17 P72 ENSG00000100201 "DEAD-box helicase 17" Q92841 22 38483440-38507660 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, mRNA processing, mRNA splicing, RNA-mediated gene silencing, rRNA processing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024908, HPA063142" Supported Supported "Nuclear speckles" "Intracellular and membrane" 90000 "Nuclear speckles" "CAB024908: , HPA063142: " "unprognostic (1.46e-2)" "unprognostic (5.99e-3)" "unprognostic (4.24e-3)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-2)" "unprognostic (1.36e-2)" "prognostic favourable (6.06e-4)" "unprognostic (1.17e-1)" "unprognostic (5.51e-1)" "unprognostic (2.52e-2)" "unprognostic (2.73e-2)" "unprognostic (1.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" 49.7 43.1 46.3 49.2 54.5 19.8 50.8 69.7 52.0 47.7 53.3 56.5 54.4 33.1 58.5 82.9 37.5 52.2 46.1 39.9 47.0 31.2 34.3 41.9 41.5 52.6 64.0 37.7 67.8 41.5 68.5 83.7 49.4 46.0 46.2 36.8 51.4 43.9 51.8 89.2 60.3 38.7 52.7 47.1 54.1 39.7 24.6 63.1 69.3 59.8 29.2 47.7 54.5 52.9 10.3 12.4 23.7 9.5 4.0 9.9 6.1 29.6 28.8 58.8 35.3 39.0 44.9 30.7 25.3 25.3 37.0 36.0 27.5 24.8 57.6 17.5 33.1 32.8 64.3 35.9 41.4 56.7 36.7 35.8 48.2 32.9 41.8 45.7 42.6 31.3 47.1 24.1 41.7 42.2 36.9 65.2 29.3 19.3 32.1 38.9 37.8 14.0 58.3 32.8 35.3 35.1 39.7 34.0 20.0 39.7 31.4 41.9 27.1 35.3 34.2 31.6 19.7 20.1 19.0 50.4 34.8 49.6 40.8 29.6 38.8 8.5 9.5 11.0 9.9 7.3 9.4 9.0 8.0 7.1 6.8 10.3 5.8 7.5 23.7 4.0 6.8 12.4 7.9 6.1 46.3 54.5 69.7 52.0 47.0 31.2 64.0 37.7 46.0 63.1 DDX18 "Has1, MrDb" ENSG00000088205 "DEAD-box helicase 18" Q9NVP1 2 117814650-117832379 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035400, HPA041056" Approved Supported Nucleoli Nucleoli "HPA035400: AB_10672091, HPA041056: " "unprognostic (1.44e-1)" "unprognostic (2.22e-2)" "unprognostic (5.63e-2)" "prognostic unfavourable (2.64e-4)" "unprognostic (2.06e-1)" "unprognostic (1.77e-3)" "prognostic unfavourable (3.07e-4)" "unprognostic (8.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (1.42e-2)" "unprognostic (4.94e-2)" "unprognostic (8.51e-2)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (7.28e-2)" "unprognostic (5.65e-2)" 35.3 21.3 20.5 28.7 26.0 17.4 31.2 27.1 25.6 31.2 27.9 16.7 21.6 20.9 32.0 22.9 27.8 28.5 21.3 22.9 19.6 19.1 32.0 40.3 24.1 35.0 25.5 22.9 36.3 29.5 21.0 25.9 25.0 25.0 25.0 30.3 11.5 24.2 26.6 37.0 24.9 26.3 28.3 30.8 46.5 26.2 22.9 31.1 40.7 31.3 23.9 37.6 37.6 23.7 22.2 20.5 9.4 18.5 17.2 23.6 16.3 21.5 9.8 14.7 13.2 8.7 7.9 24.2 12.8 10.1 17.7 15.7 24.1 14.3 31.8 21.0 10.6 16.8 28.5 16.6 26.2 16.2 19.9 30.4 9.2 24.2 12.2 40.5 15.9 8.2 15.3 22.5 22.8 10.6 33.1 13.8 13.5 13.4 22.1 21.2 36.8 14.8 19.3 22.9 27.9 11.7 12.8 14.1 24.0 14.9 16.4 16.6 10.4 22.4 8.1 15.9 23.4 11.1 23.0 15.9 19.8 88.2 11.7 19.2 7.1 6.2 13.8 9.4 16.2 17.3 20.6 22.2 19.3 18.5 12.5 19.1 23.6 20.7 3.6 17.2 18.5 20.5 15.0 16.3 20.5 26.0 27.1 25.6 19.6 19.1 25.5 22.9 25.0 31.1 DDX19A "DDX19L, FLJ11126" ENSG00000168872 "DEAD-box helicase 19A" Q9NUU7 16 70346829-70373383 "Enzymes, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045252, HPA066668" Approved Uncertain Nucleoplasm Nucleoplasm "HPA045252: AB_10961128, HPA066668: " "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (9.07e-2)" "unprognostic (3.95e-2)" "unprognostic (2.18e-2)" "prognostic unfavourable (2.38e-4)" "prognostic unfavourable (8.05e-5)" "unprognostic (1.45e-1)" "unprognostic (1.59e-1)" "unprognostic (1.67e-1)" "unprognostic (1.30e-1)" "unprognostic (5.87e-2)" "unprognostic (1.24e-1)" "unprognostic (2.01e-2)" "unprognostic (1.49e-1)" "unprognostic (3.01e-2)" "unprognostic (6.68e-3)" 18.4 20.6 14.5 15.5 19.7 9.8 18.1 16.6 19.6 16.9 19.2 19.2 17.8 9.3 22.0 14.2 19.2 17.1 16.1 22.1 18.6 13.5 16.6 24.8 14.4 18.0 17.1 15.5 21.6 22.5 31.7 17.4 21.8 15.1 15.4 14.4 14.2 14.4 21.1 51.5 15.8 13.5 25.9 15.4 14.1 17.2 9.7 13.7 17.1 19.7 14.4 18.4 19.5 15.5 8.1 14.2 7.9 11.4 8.2 10.3 8.8 12.9 14.7 15.5 15.7 23.3 15.9 14.8 16.5 17.1 26.3 20.4 22.0 9.7 21.8 15.7 17.5 14.9 27.8 16.5 21.8 7.3 15.1 11.4 12.0 27.0 21.1 19.8 9.5 19.5 11.9 23.9 18.8 16.7 27.4 5.7 15.7 18.6 22.0 16.4 25.0 9.0 27.3 10.4 29.8 15.8 8.0 12.8 17.2 42.4 9.3 12.4 17.0 12.6 11.3 18.3 14.5 11.5 15.7 16.1 24.1 47.9 12.3 18.1 17.9 7.9 11.4 5.8 10.2 10.7 9.4 7.7 8.9 10.0 14.2 8.1 9.9 10.3 0.7 8.2 9.6 7.3 7.5 8.8 14.5 19.7 16.6 19.6 18.6 13.5 17.1 15.5 15.1 13.7 DDX19B "DBP5, DDX19" ENSG00000157349 "DEAD-box helicase 19B" Q9UMR2 16 70289663-70335283 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037229, CAB037284, HPA046380, HPA066668" Approved Uncertain Nucleoplasm Nucleoplasm "CAB037229: AB_1840791, CAB037284: AB_1840792, HPA046380: , HPA066668: " "unprognostic (2.91e-2)" "unprognostic (5.37e-2)" "unprognostic (6.48e-2)" "unprognostic (3.55e-2)" "unprognostic (3.98e-2)" "unprognostic (4.05e-2)" "unprognostic (2.93e-2)" "unprognostic (1.98e-2)" "unprognostic (1.40e-1)" "unprognostic (1.05e-1)" "unprognostic (6.33e-2)" "unprognostic (4.07e-1)" "unprognostic (7.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.50e-1)" "unprognostic (1.04e-1)" "unprognostic (6.32e-2)" 22.2 18.6 8.8 16.6 12.7 19.4 20.1 30.4 16.3 13.1 16.7 14.6 13.8 14.4 15.0 13.9 16.0 13.2 15.2 15.0 8.3 8.3 15.9 33.9 16.6 15.3 10.5 10.7 14.6 21.6 20.3 17.9 12.0 13.2 13.8 18.2 19.3 16.8 15.2 24.8 26.9 16.6 15.7 10.1 17.8 18.5 64.3 12.3 17.4 18.0 16.9 20.8 16.2 13.9 21.1 21.1 27.0 28.6 22.1 35.4 22.5 2.0 12.3 17.5 15.9 9.7 12.9 15.2 9.9 14.1 21.8 22.8 26.1 15.1 16.1 9.4 12.4 12.1 0.1 5.7 22.6 6.6 11.1 9.5 8.0 21.4 20.8 20.3 9.2 15.9 11.2 16.5 12.6 16.7 9.6 7.0 13.3 14.1 0.0 29.3 10.9 5.1 28.1 9.5 23.2 13.0 11.4 11.5 15.1 23.4 5.3 12.6 11.9 18.1 10.1 10.3 9.2 8.5 9.1 15.0 7.8 37.3 3.4 16.6 13.2 27.0 22.1 19.0 23.2 28.6 22.3 21.1 20.9 25.3 21.1 19.0 19.0 18.0 4.1 22.1 17.7 6.5 35.4 22.5 8.8 12.7 30.4 16.3 8.3 8.3 10.5 10.7 13.2 12.3 DDX20 "DP103, GEMIN3" ENSG00000064703 "DEAD-box helicase 20" Q9UHI6 1 111755245-111768016 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 81.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005516, CAB015427" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Intracellular and membrane" "Nucleoplasm, Nuclear bodies" Cytosol "CAB015427: AB_629518, HPA005516: AB_1849612" "unprognostic (3.71e-2)" "unprognostic (5.25e-2)" "prognostic favourable (9.85e-5)" "unprognostic (8.73e-2)" "unprognostic (2.51e-2)" "unprognostic (7.09e-2)" "prognostic unfavourable (6.35e-6)" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (7.46e-3)" "unprognostic (4.21e-1)" "unprognostic (5.22e-2)" "unprognostic (1.05e-3)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (4.23e-1)" "unprognostic (1.30e-2)" 3.1 2.8 2.9 2.7 4.3 5.9 9.8 5.8 5.1 2.7 2.6 1.8 2.6 2.0 4.0 2.9 2.6 3.7 1.7 2.0 4.3 1.6 2.7 2.4 4.1 3.8 2.4 1.9 3.9 2.9 4.0 3.9 2.7 3.4 2.9 2.6 1.2 2.6 2.7 5.1 2.5 3.5 2.9 5.6 4.5 2.8 81.7 3.3 5.1 3.2 1.7 4.1 2.9 5.0 11.9 7.4 12.7 7.4 10.5 14.1 7.8 11.4 4.7 12.2 11.0 8.8 7.0 11.4 11.2 8.7 16.1 15.7 7.0 4.0 26.8 8.8 7.6 9.2 14.4 11.3 18.0 12.2 13.0 13.0 9.2 7.2 8.8 12.8 9.6 7.0 9.9 13.7 13.9 11.1 12.4 9.8 12.2 10.8 15.7 13.0 15.3 9.6 15.4 20.1 6.7 10.5 9.0 12.7 11.5 10.8 13.5 18.0 8.4 13.6 9.8 9.8 14.5 17.5 13.0 4.9 6.9 20.5 10.2 13.2 22.1 12.7 7.0 6.9 10.0 7.3 13.3 11.9 11.7 11.8 7.4 10.1 14.1 12.3 5.0 10.5 7.4 5.2 11.7 7.8 2.9 4.3 5.8 5.1 4.3 1.6 2.4 1.9 3.4 3.3 DDX21 "GURDB, RH-II/GU" ENSG00000165732 "DExD-box helicase 21" Q9NR30 10 68956128-68985073 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing, Transcription" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036592, HPA036593" Enhanced Enhanced Nucleoplasm,Nucleoli 14000 Nucleoli Nucleoplasm "HPA036592: AB_10673625, HPA036593: AB_2675208" "unprognostic (3.04e-1)" "unprognostic (6.81e-3)" "unprognostic (1.13e-2)" "unprognostic (1.21e-2)" "unprognostic (1.75e-2)" "unprognostic (6.71e-3)" "unprognostic (1.34e-2)" "unprognostic (1.99e-2)" "unprognostic (1.29e-1)" "unprognostic (1.92e-1)" "prognostic unfavourable (3.12e-4)" "unprognostic (1.64e-1)" "unprognostic (1.39e-2)" "unprognostic (9.33e-2)" "unprognostic (5.41e-2)" "unprognostic (1.24e-2)" "unprognostic (5.74e-3)" 37.5 16.0 10.0 26.6 13.3 46.8 24.4 8.0 11.8 18.5 20.1 7.2 16.2 13.3 18.7 13.7 28.3 20.1 17.6 19.1 11.4 8.0 25.1 48.0 25.9 24.4 14.9 7.2 30.2 27.9 15.6 20.7 22.8 18.3 14.0 17.6 5.9 18.0 17.8 61.2 22.5 18.5 19.0 20.4 43.5 19.0 12.9 13.3 27.1 18.1 24.1 25.8 33.2 22.4 12.6 11.5 17.1 17.3 7.7 15.0 6.2 32.8 19.5 11.4 35.2 10.3 13.6 24.1 22.6 18.3 29.2 24.9 63.1 22.5 49.6 13.9 18.7 29.3 43.9 28.2 39.2 15.4 30.9 34.7 13.9 26.2 22.1 82.5 33.0 14.0 36.7 34.9 58.4 21.2 66.0 24.8 20.5 15.0 32.3 18.0 31.2 41.7 28.9 18.7 24.3 19.4 17.7 23.6 25.3 20.3 45.1 26.3 25.5 17.3 21.8 17.2 24.3 23.0 39.6 28.6 37.8 73.2 14.3 62.6 11.6 5.0 9.7 17.1 8.4 15.0 15.0 12.6 10.9 11.0 11.5 10.4 10.3 11.3 4.5 7.7 17.3 10.8 7.9 6.2 10.0 13.3 8.0 11.8 11.4 8.0 14.9 7.2 18.3 13.3 DDX23 "prp28, PRPF28, SNRNP100, U5-100K" ENSG00000174243 "DEAD-box helicase 23" Q9BUQ8 12 48829764-48852842 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038680, HPA039037" Approved Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA038680: AB_10795401, HPA039037: " "unprognostic (1.32e-3)" "unprognostic (8.90e-2)" "unprognostic (8.92e-2)" "unprognostic (7.12e-2)" "unprognostic (5.34e-2)" "unprognostic (1.47e-1)" "prognostic unfavourable (3.03e-5)" "unprognostic (3.54e-2)" "unprognostic (5.68e-2)" "unprognostic (2.19e-2)" "unprognostic (1.69e-1)" "unprognostic (8.34e-2)" "unprognostic (5.94e-2)" "unprognostic (9.78e-2)" "unprognostic (6.88e-2)" "unprognostic (2.59e-2)" "unprognostic (1.44e-1)" 26.1 26.5 29.5 35.6 34.2 19.4 27.2 32.8 35.6 26.7 32.8 23.3 27.5 27.9 31.0 22.3 31.0 31.1 25.2 25.1 29.8 20.3 25.2 37.7 27.7 35.2 26.5 25.3 36.2 30.4 32.2 28.1 34.4 25.0 29.9 32.6 24.7 31.1 27.0 44.4 30.6 32.3 29.4 24.1 40.0 30.6 24.9 32.0 46.8 28.2 29.8 38.9 28.9 47.9 12.0 11.5 19.6 13.3 11.2 19.8 10.6 21.6 49.4 23.5 24.9 23.5 16.3 25.0 26.8 20.6 30.5 19.4 48.1 28.9 27.3 29.5 22.2 19.6 50.9 24.4 26.1 42.8 27.0 36.2 42.1 21.7 12.7 36.5 33.0 15.7 22.0 32.3 19.4 24.9 47.9 24.5 22.1 30.0 34.6 34.7 34.9 23.5 37.0 27.8 21.7 18.0 30.5 29.0 16.9 26.9 30.8 11.2 30.1 33.6 22.3 23.1 16.9 11.3 21.2 18.5 25.8 33.0 19.6 25.8 12.6 17.1 11.1 19.6 19.5 13.3 19.8 12.0 14.5 17.6 10.8 11.4 14.0 16.9 11.9 11.2 8.9 11.5 13.1 10.6 29.5 34.2 32.8 35.6 29.8 20.3 26.5 25.3 25.0 32.0 DDX24 ENSG00000089737 "DEAD-box helicase 24" Q9GZR7 14 94048291-94081245 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 103.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002554 Uncertain Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA002554: AB_1078631" "unprognostic (7.48e-2)" "unprognostic (3.02e-2)" "unprognostic (8.95e-2)" "unprognostic (2.12e-1)" "unprognostic (2.31e-1)" "unprognostic (4.06e-3)" "unprognostic (8.81e-2)" "unprognostic (2.66e-3)" "unprognostic (2.77e-1)" "unprognostic (2.28e-2)" "unprognostic (1.60e-3)" "unprognostic (4.13e-2)" "prognostic favourable (3.06e-9)" "prognostic unfavourable (2.89e-4)" "unprognostic (6.15e-2)" "unprognostic (1.23e-1)" "unprognostic (5.66e-2)" 18.0 45.5 19.7 13.7 41.3 53.3 18.5 31.4 40.8 17.4 20.9 21.9 14.3 13.6 23.2 103.0 20.1 18.9 21.3 28.6 25.0 31.3 36.3 30.1 16.4 27.4 22.0 29.0 21.4 12.5 8.3 32.0 11.2 38.7 16.0 14.6 17.4 15.9 17.7 28.5 23.4 12.6 17.9 21.8 18.1 15.0 38.5 17.4 14.3 25.3 11.8 25.8 21.7 14.9 4.1 3.1 10.6 3.3 6.2 5.3 5.0 3.8 1.0 7.1 4.6 4.3 5.6 1.7 10.7 8.9 13.9 12.5 1.3 2.4 17.7 4.0 2.3 2.5 7.3 0.6 15.2 7.7 0.4 9.4 2.0 5.7 3.5 13.5 4.2 0.9 4.0 2.5 2.4 2.3 4.9 5.2 5.9 10.6 4.0 11.5 4.7 0.1 5.4 16.5 2.0 10.1 1.4 5.6 5.2 10.5 2.6 4.9 4.1 4.8 6.8 4.0 2.6 5.1 3.2 2.1 13.6 19.0 5.7 7.4 3.1 10.6 3.3 2.5 5.0 2.6 1.4 2.9 2.9 3.0 2.0 4.1 5.3 5.3 2.6 6.2 2.5 3.1 3.3 5.0 19.7 41.3 31.4 40.8 25.0 31.3 22.0 29.0 38.7 17.4 DDX25 GRTH ENSG00000109832 "DEAD-box helicase 25" Q9UHL0 11 125903348-125943702 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Translation regulation, Transport" "Developmental protein, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 17.3;testis: 64.2" "Group enriched" "Detected in some" 4 "NTERA-2: 13.6;SCLC-21H: 11.0" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020137 Enhanced "HPA020137: AB_1847552" "unprognostic (5.78e-3)" "unprognostic (9.75e-3)" "unprognostic (7.93e-2)" "unprognostic (5.09e-3)" "unprognostic (1.11e-2)" "unprognostic (1.78e-2)" "unprognostic (1.54e-1)" "unprognostic (2.91e-3)" "unprognostic (6.24e-5)" "unprognostic (2.57e-1)" "unprognostic (2.44e-3)" "unprognostic (3.89e-1)" "unprognostic (3.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.69e-1)" 0.7 2.8 8.7 0.8 13.2 0.9 0.8 7.9 17.3 0.8 0.8 2.0 0.0 1.0 0.9 0.9 0.8 0.9 0.8 0.7 8.4 7.1 2.7 0.8 0.8 0.8 4.8 8.9 1.2 1.8 2.6 7.1 0.9 5.9 0.9 0.8 2.3 0.8 1.0 0.8 1.6 0.8 0.7 3.4 0.9 1.0 64.2 3.0 0.0 4.3 0.0 0.8 0.7 0.2 0.6 0.5 3.3 0.3 1.3 0.5 0.1 0.0 0.0 2.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.9 0.0 0.2 1.5 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.6 2.0 0.1 13.6 0.0 0.5 0.0 0.0 0.0 0.1 11.0 2.5 0.2 0.0 1.9 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.8 2.1 0.3 0.6 0.3 0.2 0.2 0.4 0.5 0.2 0.1 0.6 0.4 0.3 3.3 1.3 0.2 0.5 0.1 0.1 8.7 13.2 7.9 12.5 8.4 7.1 4.8 8.9 5.9 3.0 DDX27 "dJ686N3.1, DRS1" ENSG00000124228 "DEAD-box helicase 27" Q96GQ7 20 49219295-49244077 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047087 Uncertain Approved Nucleoli Nucleoli "HPA047087: AB_10964059" "unprognostic (4.47e-2)" "unprognostic (2.41e-2)" "unprognostic (3.13e-1)" "prognostic unfavourable (1.44e-5)" "unprognostic (2.82e-1)" "unprognostic (7.12e-2)" "prognostic unfavourable (6.70e-7)" "unprognostic (2.28e-1)" "unprognostic (9.53e-2)" "unprognostic (2.74e-1)" "unprognostic (7.18e-2)" "unprognostic (5.84e-3)" "prognostic unfavourable (1.73e-4)" "unprognostic (1.26e-1)" "unprognostic (4.32e-1)" "unprognostic (1.99e-2)" "unprognostic (1.27e-1)" 22.0 22.5 21.9 33.0 23.2 40.9 23.6 34.8 26.3 24.3 26.4 16.3 20.4 23.2 26.2 19.1 26.5 23.9 27.1 19.2 22.6 17.3 25.9 21.0 20.1 32.3 19.9 18.8 37.4 27.3 25.9 25.6 23.9 21.2 22.0 22.1 14.4 22.9 24.3 32.9 27.8 33.6 20.0 20.7 34.1 22.9 25.0 24.0 30.6 23.5 19.4 35.3 24.0 27.2 30.4 28.0 22.2 24.2 18.2 26.7 18.6 20.1 19.1 9.8 7.5 11.0 10.1 28.0 13.4 11.0 42.3 19.6 62.3 22.6 24.0 25.0 10.9 28.6 21.8 21.5 31.5 8.4 12.8 18.2 16.1 30.2 16.1 23.0 21.3 10.7 25.2 24.6 19.0 7.0 24.7 13.3 13.7 13.5 24.2 30.4 18.6 24.9 20.9 24.5 22.0 15.3 15.6 12.8 15.2 37.4 54.0 22.5 28.5 26.7 8.7 27.2 24.0 22.7 27.8 15.2 16.3 31.4 17.4 18.3 17.5 11.1 19.8 22.2 21.7 21.2 22.8 29.4 20.6 19.7 23.3 30.4 26.7 20.3 8.1 18.2 24.2 28.0 26.3 18.6 21.9 23.2 34.8 26.3 22.6 17.3 19.9 18.8 21.2 24.0 DDX28 "FLJ11282, MDDX28" ENSG00000182810 "DEAD-box helicase 28" Q9NUL7 16 68021274-68023442 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041911, HPA053585" Approved Supported Nucleoli,Mitochondria,Cytosol "Mitochondria, Cytosol" Nucleoli "HPA041911: AB_10794161, HPA053585: " "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (6.10e-3)" "unprognostic (8.03e-2)" "unprognostic (1.58e-1)" "unprognostic (8.69e-2)" "unprognostic (8.46e-2)" "unprognostic (9.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.63e-2)" "unprognostic (8.14e-3)" "unprognostic (8.53e-2)" "prognostic favourable (2.07e-10)" "unprognostic (1.58e-2)" "unprognostic (6.21e-2)" "unprognostic (2.23e-1)" "unprognostic (2.47e-1)" 9.8 12.7 6.2 6.7 8.3 19.7 7.1 6.0 12.9 8.3 7.2 6.4 6.8 5.2 7.5 7.3 9.7 7.1 7.0 9.2 5.2 5.9 8.9 12.4 5.8 18.4 6.4 5.1 8.6 13.3 6.8 4.6 17.1 6.6 6.1 6.0 7.8 6.3 5.2 16.2 9.9 7.9 5.3 3.0 11.1 7.0 11.5 2.7 14.6 10.2 7.3 10.6 8.0 4.8 17.8 18.0 22.9 19.1 17.0 22.9 16.6 6.1 9.1 4.5 5.4 6.3 3.5 10.5 4.2 6.2 10.6 7.6 8.8 9.8 23.0 6.5 5.2 11.1 6.4 10.2 6.3 3.1 10.5 8.3 4.8 9.1 8.5 13.0 9.0 6.8 11.1 8.7 8.0 5.9 14.8 3.6 4.7 13.7 13.6 18.3 11.0 6.8 13.4 4.2 24.6 7.4 7.1 9.4 6.3 17.1 4.9 9.3 9.4 14.3 4.2 4.7 4.0 6.7 6.9 8.1 9.8 22.1 5.8 10.1 6.3 17.7 19.1 22.9 15.7 18.8 17.3 12.6 14.6 16.9 18.0 17.8 22.9 16.9 6.3 17.0 18.5 9.0 13.8 16.6 6.2 8.3 6.0 12.9 5.2 5.9 6.4 5.1 6.6 2.7 DDX31 "FLJ13633, FLJ14578, FLJ23349, PPP1R25" ENSG00000125485 "DEAD-box helicase 31" Q9H8H2 9 132592997-132670401 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020891 Supported "Nucleoli,Golgi apparatus,Vesicles" Nucleoli "Golgi apparatus, Vesicles" "HPA020891: " "unprognostic (5.71e-2)" "unprognostic (1.76e-2)" "unprognostic (2.56e-1)" "unprognostic (7.91e-2)" "unprognostic (5.79e-2)" "unprognostic (9.94e-2)" "prognostic unfavourable (1.68e-7)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.66e-1)" "unprognostic (3.90e-2)" "unprognostic (9.57e-3)" "unprognostic (4.57e-3)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" 6.8 6.9 8.2 15.3 11.2 6.0 12.3 18.4 8.5 7.5 6.6 9.4 12.6 5.0 8.9 8.8 9.8 8.8 7.5 5.4 6.3 6.3 8.4 9.2 12.0 15.1 9.1 5.7 16.9 17.3 10.0 8.8 5.8 9.8 9.2 8.0 7.4 12.7 12.6 12.9 14.0 7.2 12.7 12.9 8.7 6.8 15.2 8.3 6.8 22.7 10.8 13.8 7.2 12.6 5.0 4.5 1.9 2.7 3.1 6.9 3.0 7.1 13.2 6.5 8.9 7.9 7.2 12.7 7.6 7.5 12.1 9.2 14.7 14.7 17.8 7.0 7.1 20.0 20.3 8.9 9.7 10.9 7.5 9.6 11.8 7.7 9.6 17.1 7.9 6.3 12.2 12.3 17.4 7.9 17.7 7.0 10.0 15.3 11.9 9.3 16.0 13.6 12.6 11.5 20.5 11.0 6.8 11.7 8.3 14.0 12.4 10.6 26.0 5.0 6.6 20.5 9.3 11.6 11.8 3.4 10.7 13.9 7.4 10.9 15.4 0.0 1.9 1.9 5.7 2.7 4.7 4.2 5.5 4.4 4.5 5.0 6.9 5.1 0.3 3.1 1.9 2.8 3.6 3.0 8.2 11.2 18.4 8.5 6.3 6.3 9.1 5.7 9.8 8.3 DDX39A "BAT1L, DDX39, DDXL, URH49" ENSG00000123136 "DExD-box helicase 39A" O00148 19 14408819-14419383 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 60.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055334 Approved Approved "Nuclear speckles" "Nuclear speckles" "HPA055334: " "unprognostic (1.31e-1)" "prognostic favourable (6.86e-4)" "unprognostic (2.41e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (5.20e-2)" "unprognostic (2.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.87e-1)" "unprognostic (8.81e-2)" "unprognostic (1.64e-1)" "unprognostic (3.09e-2)" "prognostic unfavourable (1.50e-10)" "unprognostic (1.55e-3)" "unprognostic (8.57e-2)" "unprognostic (3.92e-1)" "unprognostic (7.38e-3)" 10.9 8.5 7.2 20.6 11.4 41.4 10.5 9.1 7.9 8.2 10.9 11.0 4.4 13.0 9.4 7.2 15.9 7.0 8.1 7.8 6.6 6.1 9.7 12.1 10.3 31.2 12.6 5.0 7.4 8.8 3.0 7.4 10.5 10.0 7.3 8.9 5.2 7.9 4.4 7.9 10.6 12.8 6.8 9.4 23.4 10.4 60.7 10.3 39.9 8.4 16.3 26.1 10.3 8.8 36.7 36.6 7.7 28.5 21.5 39.7 33.6 32.6 26.8 13.8 26.6 5.7 4.1 13.5 14.5 8.1 30.3 18.7 27.2 17.7 63.2 15.5 12.0 20.2 33.9 23.6 12.4 22.0 17.7 67.8 31.3 19.5 10.0 36.8 30.3 5.7 5.3 19.7 8.0 15.8 41.6 27.8 16.8 39.5 63.1 54.7 26.3 41.1 43.8 24.4 36.9 10.8 26.9 32.1 17.7 10.8 22.6 16.3 24.9 36.0 14.8 26.8 16.7 44.1 32.5 28.9 50.7 65.0 30.1 40.3 26.8 6.8 25.9 7.7 35.6 28.5 30.5 36.7 28.4 28.2 36.6 33.2 24.9 26.7 7.7 21.5 23.4 22.6 39.7 33.6 7.2 11.4 9.1 7.9 6.6 6.1 12.6 5.0 10.0 10.3 DDX39B "BAT1, D6S81E, UAP56" ENSG00000198563 "DExD-box helicase 39B" Q13838 6 31530219-31542448 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Transport" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034012, HPA055334, HPA058450" Enhanced Enhanced "Nuclear speckles" 120000 "Nuclear speckles" "CAB034012: AB_2243237, HPA055334: , HPA058450: " "unprognostic (2.78e-2)" "unprognostic (1.30e-2)" "unprognostic (6.86e-3)" "unprognostic (3.44e-2)" "unprognostic (3.22e-2)" "unprognostic (5.13e-3)" "unprognostic (2.89e-2)" "unprognostic (1.19e-2)" "unprognostic (4.89e-3)" "unprognostic (1.25e-1)" "unprognostic (2.81e-2)" "unprognostic (3.53e-3)" "prognostic unfavourable (1.11e-6)" "unprognostic (2.85e-1)" "unprognostic (1.72e-1)" "unprognostic (1.90e-2)" "prognostic favourable (1.43e-5)" 27.1 31.0 16.1 33.3 20.6 11.3 29.1 37.3 22.7 34.9 35.4 31.8 25.6 8.2 53.4 75.4 40.2 43.5 23.8 28.3 16.3 12.8 25.3 28.6 29.1 26.5 19.2 15.6 49.8 36.8 17.6 50.6 25.9 19.7 35.3 19.3 35.3 26.4 34.4 39.0 24.7 33.2 25.8 30.8 39.9 27.7 21.3 17.8 45.5 31.2 30.5 37.1 32.9 27.7 5.1 8.5 3.8 6.2 3.4 7.4 5.5 3.0 16.1 13.3 6.5 13.5 11.6 7.7 3.4 3.9 10.0 9.0 4.0 4.0 3.1 11.7 16.7 5.6 15.1 25.6 9.4 2.7 40.3 5.5 4.7 9.6 4.5 7.4 6.0 17.9 15.4 10.1 31.7 6.3 23.8 2.5 8.3 2.1 6.5 27.0 5.6 2.8 5.5 5.9 3.6 20.2 3.9 6.1 17.0 6.8 3.1 3.9 2.3 6.4 3.5 1.3 4.8 1.2 8.9 10.2 12.6 25.0 0.8 10.4 5.3 3.5 6.1 3.8 5.4 6.2 6.7 4.5 6.8 6.5 8.5 5.1 7.4 6.8 3.4 3.4 5.6 6.5 7.3 5.5 16.1 20.6 37.3 22.7 16.3 12.8 19.2 15.6 19.7 17.8 DDX3X "DBX, DDX14, DDX3, HLP2" ENSG00000215301 "DEAD-box helicase 3, X-linked" O00571 X 41333284-41364472 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059585" Supported Supported Approved Nucleoplasm,Cytosol 110000 Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: " "unprognostic (2.42e-2)" "unprognostic (1.11e-1)" "unprognostic (8.01e-3)" "unprognostic (1.66e-1)" "unprognostic (8.12e-2)" "unprognostic (6.43e-2)" "unprognostic (1.17e-3)" "unprognostic (1.88e-1)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.25e-2)" "unprognostic (2.05e-1)" "unprognostic (1.51e-1)" "unprognostic (2.95e-1)" "unprognostic (4.77e-1)" "unprognostic (9.44e-2)" "unprognostic (2.93e-2)" 80.9 49.3 26.1 40.0 34.5 49.3 46.5 31.1 36.2 52.4 43.3 35.1 21.3 29.5 56.4 25.9 53.5 56.3 42.6 47.6 30.8 24.5 55.6 77.9 45.3 40.4 41.4 29.0 60.1 30.9 68.7 60.2 79.9 37.9 30.0 29.2 30.8 37.4 26.5 63.4 42.2 54.0 57.2 53.9 46.1 43.0 27.0 39.0 49.2 45.6 44.0 42.6 55.8 50.2 13.1 20.5 32.0 21.6 17.3 21.5 17.9 45.4 50.5 47.2 25.9 55.6 47.2 28.8 33.1 46.6 34.0 27.4 51.9 30.6 0.5 23.7 37.1 30.7 57.7 46.6 56.7 26.9 45.0 28.9 50.3 31.2 28.9 54.1 52.0 34.1 33.1 57.3 55.4 53.3 53.0 28.6 31.6 34.4 34.1 16.9 45.4 20.4 40.0 50.3 37.0 32.0 61.2 32.3 48.9 75.0 38.5 39.7 34.6 36.8 48.1 35.1 37.6 37.5 39.3 33.4 39.6 44.9 35.4 32.8 33.2 22.5 20.2 17.5 14.8 21.1 21.5 13.1 14.5 16.3 20.5 9.0 16.3 15.1 32.0 17.3 21.6 6.9 14.3 17.9 26.1 34.5 31.1 36.2 30.8 24.5 41.4 29.0 37.9 39.0 DDX3Y DBY ENSG00000067048 "DEAD-box helicase 3, Y-linked" O15523 Y 12904108-12920478 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 40.6;HEL: 41.4;U-266/84: 34.4;U-698: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059583" Enhanced Supported Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059583: " "unprognostic (3.89e-2)" "unprognostic (1.70e-1)" "prognostic favourable (4.70e-5)" "unprognostic (6.50e-2)" "unprognostic (4.74e-2)" "unprognostic (2.22e-2)" "unprognostic (4.17e-2)" "unprognostic (3.37e-2)" "unprognostic (9.61e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-1)" "unprognostic (2.66e-2)" "unprognostic (7.87e-2)" 12.0 10.5 4.9 29.5 14.1 46.1 8.7 17.0 16.3 0.4 24.4 12.6 31.5 7.6 0.4 29.7 12.2 0.4 14.2 10.8 5.6 7.1 8.9 26.5 20.0 17.7 5.7 0.0 0.4 14.5 0.4 12.2 14.0 20.2 26.7 15.8 15.1 20.4 32.6 17.7 8.4 16.0 40.7 6.2 34.3 8.9 41.9 0.0 26.9 10.8 21.4 19.3 14.4 0.0 6.1 8.8 6.5 7.1 6.5 8.4 3.8 0.1 7.5 0.0 0.0 0.0 0.0 5.5 18.6 13.3 9.8 12.1 0.0 0.0 40.6 0.0 18.3 0.0 0.0 0.0 17.3 10.2 0.0 41.4 0.0 12.2 9.7 0.0 0.0 10.3 11.6 0.0 0.0 0.0 0.0 0.0 11.6 0.0 16.0 0.0 7.4 0.0 0.0 4.9 7.4 10.5 11.2 12.2 0.0 0.0 0.0 13.6 0.0 9.7 13.3 15.3 0.0 0.0 12.2 21.9 34.4 30.2 1.8 0.0 0.0 1.6 6.2 5.7 8.4 7.1 7.7 6.1 6.4 7.1 8.8 5.9 7.8 6.5 6.5 6.5 4.6 2.5 5.7 3.8 4.9 14.1 17.0 16.3 5.6 7.1 5.7 0.0 20.2 0.0 DDX4 VASA ENSG00000152670 "DEAD-box helicase 4" Q9NQI0 5 55738017-55817157 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 171 "testis: 60.4" "Cell line enhanced" "Detected in some" "BEWO: 5.9;HEK 293: 1.6;NB-4: 1.0;PC-3: 3.3" "Cancer enriched" "Detected in single" 37 "testis cancer: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026170, HPA037763, HPA037764" Enhanced "CAB026170: , HPA037763: , HPA037764: " "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (1.54e-1)" "unprognostic (2.58e-1)" "unprognostic (3.80e-2)" "unprognostic (3.03e-1)" "unprognostic (5.35e-2)" "unprognostic (3.91e-1)" "unprognostic (3.77e-2)" "unprognostic (3.28e-1)" "unprognostic (5.73e-2)" "unprognostic (5.43e-7)" "unprognostic (4.84e-2)" "unprognostic (1.12e-1)" "unprognostic (5.60e-2)" "unprognostic (1.55e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 60.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 3.3 0.0 0.1 0.0 0.7 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 DDX41 "ABS, MGC8828" ENSG00000183258 "DEAD-box helicase 41" Q9UJV9 5 177511577-177517469 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017911, HPA048803" Supported Supported Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA017911: AB_1847558, HPA048803: " "unprognostic (2.52e-1)" "unprognostic (1.51e-1)" "unprognostic (7.57e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-1)" "unprognostic (2.61e-2)" "unprognostic (4.21e-3)" "unprognostic (2.60e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (4.47e-2)" "prognostic unfavourable (2.21e-6)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (1.75e-1)" 17.9 22.7 27.0 25.1 30.7 17.2 16.5 22.8 39.2 19.1 21.2 16.9 18.5 25.5 19.5 16.5 23.0 22.1 17.1 15.3 29.3 20.1 23.7 29.3 16.8 19.9 22.1 24.8 21.2 18.0 22.2 15.1 22.1 27.4 16.3 15.4 19.0 19.0 17.5 36.6 21.7 26.8 16.7 14.8 21.9 19.7 16.8 15.4 24.9 22.9 18.2 23.5 19.6 18.4 15.9 22.5 16.4 22.8 18.6 20.6 18.0 21.0 24.1 13.2 15.5 13.6 16.1 44.5 18.9 11.5 13.9 10.3 39.2 19.7 23.6 28.8 17.8 17.3 17.2 43.3 9.5 56.4 21.6 30.0 24.5 23.2 18.0 31.0 31.9 15.8 15.3 13.2 17.8 17.7 26.0 16.9 16.4 45.4 25.8 15.2 23.2 19.5 28.1 16.0 27.8 15.5 24.5 15.7 17.2 20.1 26.8 22.6 18.7 45.3 18.9 25.5 15.1 16.2 29.4 20.3 23.8 40.3 27.9 34.2 16.7 10.6 22.8 16.4 16.1 21.5 20.6 15.9 16.0 15.3 22.5 14.1 14.8 15.5 7.7 18.6 21.4 10.2 15.6 18.0 27.0 30.7 22.8 39.2 29.3 20.1 22.1 24.8 27.4 15.4 DDX42 "RHELP, RNAHP, SF3b125, SF3B8" ENSG00000198231 "DEAD-box helicase 42" Q86XP3 17 63773603-63819317 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023447, HPA023571, HPA025941" Approved Enhanced "Nuclear speckles" "Nuclear speckles" "HPA023447: AB_1847560, HPA023571: AB_1847561, HPA025941: AB_1847562" "unprognostic (3.46e-1)" "unprognostic (7.11e-2)" "unprognostic (8.44e-2)" "unprognostic (1.29e-1)" "unprognostic (2.49e-2)" "unprognostic (3.17e-2)" "prognostic unfavourable (2.84e-4)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (1.90e-1)" "unprognostic (2.54e-2)" "unprognostic (1.34e-2)" "prognostic unfavourable (9.26e-4)" "unprognostic (3.02e-1)" "unprognostic (2.42e-1)" "unprognostic (7.35e-2)" "unprognostic (1.55e-2)" 32.4 28.2 27.1 26.3 39.4 24.2 32.5 34.1 40.7 39.1 31.2 33.7 20.9 23.0 39.2 30.7 26.1 34.4 35.1 25.6 25.6 26.7 23.0 25.7 26.4 27.5 29.6 35.8 43.5 41.8 36.8 26.2 30.7 34.1 39.0 28.0 28.8 34.0 35.6 44.7 29.2 26.7 37.7 27.3 26.9 30.5 28.6 21.5 33.2 26.1 21.8 33.7 42.6 25.4 7.6 5.0 8.4 4.4 6.7 6.6 2.8 30.8 32.5 29.3 30.0 29.7 24.1 31.6 30.5 27.4 27.9 27.4 30.5 20.5 43.2 11.9 34.0 24.8 33.0 27.0 37.0 12.7 21.7 32.5 31.5 37.0 29.3 37.6 22.3 30.6 25.8 25.2 30.7 27.6 36.1 18.3 28.3 25.2 35.9 21.0 27.9 17.4 31.4 50.3 22.1 25.5 36.5 18.5 35.0 23.0 41.5 25.9 28.4 31.1 29.3 41.3 25.2 16.7 35.7 20.6 16.4 39.8 21.2 20.9 21.6 2.6 3.9 8.4 6.2 3.2 6.6 4.1 5.2 6.1 5.0 7.6 6.6 6.4 2.9 6.7 4.4 3.0 3.1 2.8 27.1 39.4 34.1 40.7 25.6 26.7 29.6 35.8 34.1 21.5 DDX43 "CT13, DKFZp434H2114, HAGE" ENSG00000080007 "DEAD-box helicase 43" Q9NXZ2 6 73394748-73417569 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 35.2" "Cell line enhanced" "Detected in some" "BEWO: 8.8;CAPAN-2: 14.8;HHSteC: 4.1;U-2 OS: 9.5" "Cancer enriched" "Detected in many" 15 "testis cancer: 13.0" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031381 Enhanced "HPA031381: AB_10601885" "unprognostic (4.03e-3)" "unprognostic (8.20e-2)" "unprognostic (2.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.19e-1)" "unprognostic (3.59e-4)" "unprognostic (1.64e-2)" "unprognostic (3.11e-2)" "unprognostic (1.20e-1)" "unprognostic (2.15e-1)" "unprognostic (3.12e-1)" "unprognostic (3.08e-1)" "unprognostic (1.19e-3)" "unprognostic (1.02e-1)" "unprognostic (2.68e-1)" "unprognostic (1.58e-1)" "unprognostic (8.78e-2)" 1.3 0.7 0.6 1.0 0.7 0.7 1.9 0.4 0.8 0.8 2.6 1.2 2.1 1.4 1.0 0.4 1.1 0.7 6.1 1.2 0.7 0.6 0.8 1.0 1.6 0.9 1.0 0.0 2.9 1.9 0.1 0.7 5.7 3.3 1.8 0.7 1.5 4.3 2.2 0.4 1.4 1.7 3.0 1.9 1.2 2.4 35.2 0.7 0.4 1.8 1.3 1.9 1.7 0.7 2.3 0.8 2.9 0.9 1.6 3.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.5 0.0 0.0 0.0 0.1 14.8 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 2.9 3.3 0.9 2.6 2.3 2.5 2.8 0.8 2.3 1.3 0.4 0.6 1.6 0.8 0.2 1.4 0.7 0.6 0.7 0.4 0.8 0.7 0.6 1.0 0.0 3.3 0.7 DDX46 "FLJ25329, KIAA0801, Prp5, PRPF5" ENSG00000145833 "DEAD-box helicase 46" Q7L014 5 134758771-134855133 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036554, HPA057501" Supported Enhanced "Nuclear speckles" "Nuclear speckles" "HPA036554: AB_10673621, HPA057501: AB_2683449" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "prognostic favourable (9.01e-6)" "unprognostic (7.00e-2)" "unprognostic (3.37e-2)" "unprognostic (1.71e-2)" "unprognostic (2.04e-3)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (5.05e-2)" "unprognostic (9.21e-2)" "unprognostic (6.02e-2)" "unprognostic (9.70e-3)" "unprognostic (4.36e-2)" "unprognostic (4.35e-2)" "unprognostic (1.64e-2)" "unprognostic (4.50e-2)" 22.2 21.8 18.8 29.4 23.8 22.7 22.7 39.0 24.8 25.1 21.4 17.5 18.6 19.0 26.8 19.8 23.7 21.0 15.8 18.3 17.7 13.0 22.9 22.7 21.6 26.6 22.9 15.1 25.8 24.2 27.2 37.5 22.1 21.7 19.0 24.2 12.8 23.9 23.3 46.6 26.3 23.0 24.6 27.8 30.0 22.2 17.8 25.9 40.4 22.1 21.0 29.1 23.1 28.9 27.0 23.5 34.6 19.9 19.4 20.4 9.7 25.7 23.6 16.8 21.9 6.6 7.4 23.3 17.2 13.4 18.3 20.6 35.7 18.8 32.5 14.9 11.5 16.0 24.7 16.4 21.6 21.8 22.5 39.1 25.8 14.4 5.7 35.4 21.1 6.6 9.0 19.2 10.9 14.4 33.2 14.0 13.5 12.3 30.4 13.8 23.2 10.7 26.6 44.0 16.4 10.0 22.3 20.0 19.1 24.1 11.5 12.5 17.9 20.3 17.9 19.4 13.5 14.8 34.1 11.0 29.9 43.1 13.4 33.8 12.2 25.7 19.9 27.6 20.0 17.5 18.0 22.0 19.6 19.8 15.2 27.0 20.4 20.3 34.6 19.4 15.7 23.5 17.1 9.7 18.8 23.8 39.0 24.8 17.7 13.0 22.9 15.1 21.7 25.9 DDX47 "DKFZp564O176, FLJ30012, HQ0256, RRP3" ENSG00000213782 "DEAD-box helicase 47" Q9H0S4 12 12813316-12829981 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014855 Approved Supported Nucleoli Nucleoli "HPA014855: AB_1847567" "unprognostic (3.14e-2)" "unprognostic (1.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.75e-2)" "unprognostic (2.38e-1)" "unprognostic (4.91e-2)" "unprognostic (5.84e-4)" "unprognostic (1.96e-1)" "unprognostic (1.11e-2)" "unprognostic (1.13e-3)" "unprognostic (2.79e-1)" "unprognostic (3.49e-3)" "unprognostic (6.55e-9)" "unprognostic (1.68e-1)" "unprognostic (1.27e-1)" "unprognostic (3.24e-1)" "unprognostic (8.20e-6)" 29.3 24.1 19.9 21.6 25.6 31.0 29.1 27.4 26.9 26.7 26.2 28.2 21.4 16.0 33.7 21.0 28.9 27.5 17.9 22.6 20.0 19.4 29.6 38.1 23.2 26.1 28.2 19.9 33.7 31.0 25.8 23.8 27.6 25.1 29.2 24.2 25.5 27.1 27.7 40.6 28.1 20.4 34.1 21.4 25.6 28.0 26.8 29.8 29.7 39.4 27.9 33.7 35.7 26.7 22.0 25.0 3.5 19.1 16.6 26.0 14.0 39.6 17.2 16.9 13.7 16.6 16.4 28.8 17.1 19.6 36.5 34.2 25.9 25.6 20.4 6.7 23.1 25.9 24.2 19.7 41.1 28.8 17.3 18.7 12.8 14.7 14.1 21.2 12.0 15.8 18.7 21.6 17.9 28.0 18.0 4.6 19.9 14.2 17.2 14.7 74.0 10.5 19.1 32.8 12.3 22.2 28.6 7.4 18.8 20.7 13.3 17.0 5.4 16.1 12.5 14.7 35.8 9.4 25.6 6.5 11.8 37.0 15.7 11.1 16.9 3.3 14.4 3.5 21.8 19.1 26.0 22.0 19.4 20.1 25.0 21.2 25.8 24.2 1.7 16.6 18.2 14.7 18.7 14.0 19.9 25.6 27.4 26.9 20.0 19.4 28.2 19.9 25.1 29.8 DDX49 "Dbp8, FLJ10432" ENSG00000105671 "DEAD-box helicase 49" Q9Y6V7 19 18919675-18928633 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041870, HPA048093" Enhanced Approved Nucleoli,Mitochondria Mitochondria Nucleoli "HPA041870: , HPA048093: " "unprognostic (3.51e-1)" "prognostic favourable (2.01e-6)" "unprognostic (2.28e-2)" "unprognostic (1.28e-1)" "unprognostic (8.56e-2)" "unprognostic (1.60e-2)" "prognostic unfavourable (7.05e-4)" "unprognostic (4.12e-2)" "unprognostic (2.41e-3)" "unprognostic (8.67e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "prognostic unfavourable (7.44e-5)" "unprognostic (3.93e-2)" "unprognostic (2.99e-2)" "unprognostic (4.97e-2)" "unprognostic (3.24e-1)" 14.8 16.8 17.6 17.3 16.9 28.3 18.0 17.0 30.7 15.3 15.8 19.0 14.8 19.5 15.6 13.2 23.4 16.5 12.2 18.2 19.2 12.9 15.5 25.6 13.0 19.3 15.7 14.8 15.7 26.8 13.0 11.1 23.3 16.2 15.5 10.3 13.5 24.3 15.8 27.2 23.6 18.7 12.7 16.8 16.7 15.7 19.7 16.3 23.4 18.8 16.6 18.7 16.4 15.6 8.2 25.0 13.5 19.5 14.1 14.0 9.7 15.8 16.5 6.7 21.0 9.8 7.9 25.2 10.1 6.9 17.9 14.5 18.8 16.1 20.8 30.9 10.0 13.7 14.9 13.9 5.1 6.3 39.6 10.2 17.9 16.3 23.3 26.2 14.2 15.8 13.4 14.2 15.1 8.1 19.2 14.9 6.3 35.5 18.9 12.2 21.8 40.3 21.0 11.2 22.5 9.6 10.0 23.6 24.3 13.3 13.2 16.1 13.6 12.6 10.4 8.7 9.9 31.5 16.5 19.6 23.4 19.0 11.1 30.2 13.6 10.5 17.7 13.5 12.8 19.5 10.6 8.1 9.7 9.6 25.0 8.2 9.7 10.2 7.9 14.1 12.6 11.2 14.0 9.7 17.6 16.9 17.0 30.7 19.2 12.9 15.7 14.8 16.2 16.3 DDX5 "G17P1, HLR1, p68" ENSG00000108654 "DEAD-box helicase 5" P17844 17 64499616-64508199 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005868, HPA020043" Supported Enhanced Nucleoplasm 150000 Nucleoplasm "CAB005868: AB_446484, HPA020043: AB_1847572" "unprognostic (6.64e-2)" "unprognostic (6.98e-2)" "prognostic favourable (2.12e-4)" "unprognostic (8.94e-2)" "unprognostic (5.08e-2)" "unprognostic (9.85e-2)" "unprognostic (5.80e-2)" "unprognostic (1.61e-2)" "unprognostic (3.17e-2)" "unprognostic (4.71e-2)" "unprognostic (3.03e-3)" "unprognostic (1.44e-1)" "unprognostic (4.00e-1)" "unprognostic (2.08e-1)" "unprognostic (2.37e-1)" "unprognostic (2.17e-1)" "unprognostic (9.28e-3)" 91.6 61.4 46.9 80.0 68.0 108.3 94.7 61.6 58.9 81.6 81.1 53.3 104.2 27.4 106.7 94.5 64.5 96.9 101.4 53.9 48.5 30.6 53.1 68.0 84.8 70.9 62.8 44.1 74.0 49.3 88.9 110.5 56.6 73.1 59.5 55.4 50.9 62.2 103.6 77.6 59.7 54.7 113.1 71.0 67.6 69.0 39.7 57.8 82.1 81.1 77.7 69.3 91.0 63.9 46.9 59.6 66.4 66.2 40.3 60.8 109.8 54.0 20.4 61.8 39.1 57.2 53.9 39.3 53.6 69.2 65.7 65.9 22.1 33.1 79.3 30.7 70.4 32.2 66.5 61.7 74.4 28.1 47.7 51.6 15.5 16.9 41.9 65.6 55.0 60.7 53.3 60.1 46.9 70.2 40.8 67.8 50.6 32.2 137.1 19.1 36.0 63.0 85.9 65.2 55.8 40.3 25.9 43.4 72.9 52.0 50.5 65.3 47.3 36.9 49.3 40.0 44.7 43.1 55.5 37.9 74.6 140.0 42.4 32.3 47.1 66.4 62.5 66.4 53.7 56.9 60.8 46.9 42.9 51.7 59.6 46.8 44.5 43.1 37.8 40.3 66.2 37.0 50.2 109.8 46.9 68.0 61.6 58.9 48.5 30.6 62.8 44.1 73.1 57.8 DDX50 "GU2, GUB, MGC3199, RH-II/GuB" ENSG00000107625 "DExD-box helicase 50" Q9BQ39 10 68901278-68946847 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037388, HPA037389, HPA058196" Approved Enhanced Nucleoli Nucleoli "HPA037388: AB_10671752, HPA037389: , HPA058196: " "unprognostic (2.05e-1)" "unprognostic (3.36e-1)" "unprognostic (9.90e-2)" "unprognostic (9.75e-2)" "unprognostic (1.29e-1)" "unprognostic (1.23e-1)" "unprognostic (1.47e-3)" "unprognostic (2.62e-1)" "unprognostic (1.97e-1)" "unprognostic (8.78e-2)" "unprognostic (4.57e-2)" "unprognostic (1.44e-1)" "unprognostic (4.22e-3)" "unprognostic (1.22e-2)" "unprognostic (2.38e-2)" "unprognostic (4.91e-2)" "unprognostic (1.02e-1)" 25.0 17.8 16.7 25.5 19.2 14.7 24.8 20.8 17.0 26.5 25.3 13.1 24.0 12.9 30.0 22.6 24.0 23.0 17.5 20.3 15.7 15.0 18.6 16.1 16.4 24.5 17.6 15.0 35.3 24.1 24.9 35.2 23.0 16.1 30.0 18.1 12.6 19.5 25.0 26.6 18.3 17.4 31.9 18.3 22.0 19.9 25.6 17.3 33.0 26.1 21.5 25.7 35.4 27.2 14.2 10.3 10.7 12.2 13.8 20.2 10.9 19.3 12.5 22.2 27.5 18.9 24.7 14.2 20.7 22.8 18.7 17.7 28.0 16.9 25.2 12.5 18.2 17.4 21.5 15.2 23.4 22.1 16.3 13.5 12.4 12.2 19.1 28.1 16.9 19.0 15.9 17.8 49.8 15.0 24.1 15.4 23.0 15.5 26.8 27.0 12.9 28.1 23.3 25.3 4.5 14.7 11.6 15.5 21.4 15.2 17.8 22.8 20.7 18.3 13.0 14.6 17.1 16.5 28.1 20.9 18.8 21.4 15.7 29.4 8.5 5.5 7.8 10.7 15.0 12.2 18.3 13.6 18.5 15.4 10.3 14.2 20.2 17.7 2.7 13.8 9.6 10.2 16.1 10.9 16.7 19.2 20.8 17.0 15.7 15.0 17.6 15.0 16.1 17.3 DDX51 ENSG00000185163 "DEAD-box helicase 51" Q8N8A6 12 132136594-132144335 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039503 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Nucleoli" Cytosol "HPA039503: AB_10796328" "unprognostic (2.84e-3)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" "unprognostic (2.84e-1)" "unprognostic (8.66e-2)" "unprognostic (4.00e-2)" "prognostic unfavourable (4.73e-4)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (4.88e-1)" "unprognostic (3.05e-3)" "unprognostic (5.31e-2)" "unprognostic (3.97e-2)" "unprognostic (2.48e-1)" "unprognostic (4.69e-2)" "unprognostic (3.28e-1)" "unprognostic (1.65e-3)" 10.5 8.5 12.7 12.7 17.1 17.2 10.3 23.5 18.9 8.8 8.4 11.8 10.6 7.8 11.5 12.2 8.5 12.4 10.0 8.1 11.6 9.9 9.5 7.2 8.9 11.1 10.5 16.9 19.6 14.8 10.1 9.8 7.2 11.8 9.3 7.3 8.9 10.7 12.4 13.8 18.0 8.2 10.4 10.5 10.6 9.3 6.7 12.0 9.5 9.9 7.1 10.4 9.3 8.6 2.5 2.3 2.6 2.1 1.6 2.0 1.0 6.2 10.1 4.2 5.3 4.0 3.9 8.0 4.8 2.9 7.1 3.0 6.2 3.1 10.9 4.2 2.9 6.6 10.4 7.7 3.5 2.6 10.1 12.9 5.4 2.0 4.8 9.0 7.5 3.4 5.7 4.0 3.6 3.8 9.5 3.6 2.1 6.1 10.9 18.4 7.4 17.3 13.0 5.7 12.1 4.8 4.9 10.3 5.4 5.2 7.5 5.3 6.6 8.3 6.6 2.7 8.2 6.6 11.0 10.1 5.9 12.7 5.6 6.8 6.3 1.1 2.1 1.2 2.0 1.0 0.7 1.5 1.3 0.9 0.6 2.5 1.2 1.6 2.6 1.6 1.0 2.3 0.6 1.0 12.7 17.1 23.5 18.9 11.6 9.9 10.5 16.9 11.8 12.0 DDX52 ROK1 ENSG00000278053 "DExD-box helicase 52" Q9Y2R4 17 37609739-37643464 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056173 Uncertain Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA056173: " "unprognostic (1.05e-2)" "unprognostic (1.85e-1)" "prognostic favourable (9.41e-4)" "unprognostic (4.26e-2)" "unprognostic (9.96e-3)" "unprognostic (6.77e-2)" "prognostic unfavourable (2.44e-6)" "unprognostic (5.10e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (6.95e-2)" "unprognostic (5.58e-1)" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" 6.4 4.5 4.3 5.3 5.5 9.1 4.6 8.1 6.5 6.9 6.1 4.8 5.0 5.9 7.8 10.7 6.7 3.5 5.0 3.0 4.5 9.4 7.1 4.2 5.1 5.4 3.1 6.3 4.4 6.2 8.8 5.8 6.5 6.1 6.0 4.0 4.1 4.8 6.7 6.0 10.6 4.8 6.2 5.7 4.8 4.8 4.9 8.7 5.7 5.8 6.1 6.0 6.9 4.0 5.7 3.5 4.2 3.5 4.7 1.5 4.7 9.8 1.0 9.7 5.5 4.9 4.2 6.5 5.8 8.5 8.3 5.0 1.8 2.7 4.5 4.3 4.4 10.8 7.1 11.4 6.5 12.2 6.0 6.2 4.0 5.4 7.7 3.2 5.1 7.2 5.5 6.9 9.8 0.8 1.8 5.0 1.5 11.7 4.0 5.5 0.4 7.5 8.5 5.0 9.7 5.4 7.2 5.8 7.7 1.8 4.7 3.4 6.0 6.5 7.0 4.3 3.5 7.3 2.3 3.8 5.4 5.7 4.9 5.5 3.4 3.2 3.5 4.2 4.2 3.3 3.6 4.0 3.5 2.3 4.0 3.4 4.7 2.8 3.5 2.4 5.7 3.1 1.5 DDX53 "CAGE, CT26" ENSG00000184735 "DEAD-box helicase 53" Q86TM3 X 22999961-23003589 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 11.5" "Cell line enhanced" "Detected in some" "K-562: 6.2;RPMI-8226: 3.2;U-2197: 2.1;U-266/84: 14.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003186 Supported Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "HPA003186: AB_1078637" "unprognostic (5.76e-1)" "unprognostic (1.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.4 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DDX54 "APR-5, DP97, MGC2835" ENSG00000123064 "DEAD-box helicase 54" Q8TDD1 12 113157174-113185479 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028244, HPA070786" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA028244: AB_10603885, HPA070786: " "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (8.54e-2)" "unprognostic (8.57e-2)" "unprognostic (6.39e-2)" "prognostic unfavourable (1.39e-4)" "unprognostic (2.23e-2)" "unprognostic (1.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.83e-2)" "unprognostic (1.15e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.22e-1)" "unprognostic (1.24e-1)" 17.2 17.6 9.2 20.7 12.8 25.4 17.2 9.9 13.6 17.9 16.4 12.4 18.1 20.3 18.0 19.4 19.5 17.2 17.9 20.1 8.8 7.9 22.3 28.6 14.0 19.9 8.1 9.4 22.4 27.0 18.3 7.4 22.6 10.0 16.6 9.0 13.4 17.4 13.9 45.4 18.7 19.4 14.8 8.1 22.2 16.1 11.4 8.6 26.6 23.1 21.6 22.2 16.7 17.5 12.1 13.3 8.0 15.2 11.9 13.0 10.0 26.4 27.7 10.3 19.0 6.9 8.3 26.7 14.4 13.4 19.7 10.8 28.5 12.9 34.3 16.9 12.0 19.7 18.3 18.7 7.5 19.7 22.5 20.6 14.9 19.4 12.2 34.3 24.4 13.7 14.8 19.0 11.8 16.1 29.8 12.3 10.1 24.5 29.5 49.0 24.1 19.7 21.9 15.3 35.0 10.7 27.7 13.4 12.2 20.4 31.3 13.0 26.8 26.9 11.9 16.7 18.7 19.8 30.0 18.0 20.5 38.6 14.7 19.2 17.5 8.0 10.0 2.3 12.4 15.2 13.0 11.6 11.4 12.2 13.3 12.1 11.8 12.5 0.6 11.9 9.8 10.0 9.4 10.0 9.2 12.8 9.9 13.6 8.8 7.9 8.1 9.4 10.0 8.6 DDX55 KIAA1595 ENSG00000111364 "DEAD-box helicase 55" Q8NHQ9 12 123602077-123620941 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039962, HPA044101" Approved Enhanced Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA039962: , HPA044101: " "unprognostic (1.14e-1)" "unprognostic (2.30e-2)" "unprognostic (2.29e-1)" "unprognostic (3.71e-3)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "prognostic unfavourable (2.11e-9)" "unprognostic (1.60e-1)" "unprognostic (4.49e-2)" "unprognostic (7.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.67e-3)" "prognostic unfavourable (8.97e-12)" "unprognostic (9.15e-3)" "unprognostic (2.94e-1)" "unprognostic (3.47e-2)" "unprognostic (1.23e-3)" 15.0 13.5 12.3 16.4 14.0 27.7 16.3 21.4 13.9 13.0 13.2 15.7 16.2 12.0 14.7 13.2 14.2 15.0 11.8 8.8 11.4 10.9 10.2 17.8 11.2 19.9 15.6 10.3 17.5 25.9 13.8 20.3 12.3 14.4 14.4 14.5 11.9 15.2 12.6 12.6 21.4 12.9 11.9 10.5 18.8 11.6 11.2 14.8 16.9 12.2 12.5 16.5 11.9 23.1 13.4 12.8 7.3 10.0 12.2 15.7 8.5 10.0 14.2 10.9 11.0 9.4 7.5 16.5 12.4 4.6 11.1 7.7 16.1 7.3 14.8 10.0 5.4 12.3 16.6 9.2 13.0 11.1 15.1 20.0 15.7 11.9 7.1 24.6 15.8 6.2 9.8 13.1 15.3 7.9 20.4 7.9 7.8 10.3 24.1 33.5 16.9 14.2 18.2 11.7 9.7 7.8 17.4 13.0 10.8 10.1 13.1 16.9 23.4 16.0 8.1 9.6 12.6 15.6 15.3 14.6 18.0 26.9 9.1 17.7 16.3 2.8 9.2 7.3 12.0 10.0 12.7 13.4 11.6 12.5 7.5 11.3 15.7 14.7 5.6 12.2 5.9 12.8 9.1 8.5 12.3 14.0 21.4 13.9 11.4 10.9 15.6 10.3 14.4 14.8 DDX56 NOH61 ENSG00000136271 "DEAD-box helicase 56" Q9NY93 7 44565417-44575051 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019749, CAB037320" Uncertain Supported Nucleoli Nucleoli "CAB037320: , HPA019749: AB_1847579" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (5.00e-2)" "unprognostic (1.93e-1)" "unprognostic (6.08e-3)" "unprognostic (2.12e-3)" "prognostic unfavourable (1.38e-5)" "unprognostic (5.17e-2)" "unprognostic (2.76e-1)" "unprognostic (7.07e-2)" "unprognostic (1.00e-2)" "unprognostic (6.01e-3)" "prognostic unfavourable (8.41e-7)" "unprognostic (2.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.50e-1)" "unprognostic (4.90e-2)" 12.8 12.0 10.3 12.4 11.9 12.4 9.2 13.6 18.9 11.9 10.0 12.2 8.6 11.9 12.8 10.3 13.1 12.6 12.5 9.3 10.6 9.9 17.7 29.2 8.9 13.2 10.4 9.3 15.0 22.5 13.1 11.9 12.3 12.2 14.1 9.0 11.0 16.9 11.5 16.9 16.3 11.4 8.4 8.8 12.1 10.6 14.6 10.9 14.5 13.8 16.7 15.1 9.2 10.3 12.8 16.0 6.9 16.5 15.7 12.3 12.7 7.6 20.4 1.5 4.4 2.0 2.0 6.8 7.2 3.7 8.2 7.3 13.2 7.5 13.5 9.4 2.7 13.1 3.3 7.2 1.5 5.0 20.7 8.8 12.9 10.0 3.5 9.3 4.9 2.9 5.2 7.3 4.6 4.2 18.2 3.8 5.3 10.0 4.6 8.6 11.1 19.2 3.8 7.2 5.3 4.7 8.1 5.2 8.4 9.6 14.9 5.5 10.8 9.6 8.8 6.8 9.8 4.6 18.2 12.4 18.9 19.3 7.5 11.4 9.5 6.9 11.8 4.3 9.9 15.3 12.3 11.5 10.7 11.1 16.0 12.8 12.3 10.3 0.4 15.7 16.5 7.7 10.1 12.7 10.3 11.9 13.6 18.9 10.6 9.9 10.4 9.3 12.2 10.9 DDX58 "DKFZp434J1111, FLJ13599, RIG-I" ENSG00000107201 "DExD/H-box helicase 58" O95786 9 32455705-32526324 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "BJ hTERT+ SV40 Large T+: 44.8;BJ hTERT+ SV40 Large T+ RasG12V: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012643, HPA047193" Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "CAB012643: , HPA047193: " "unprognostic (1.10e-1)" "unprognostic (4.65e-2)" "unprognostic (6.56e-2)" "prognostic unfavourable (5.46e-4)" "unprognostic (2.45e-1)" "unprognostic (2.37e-1)" "unprognostic (8.15e-2)" "unprognostic (4.57e-2)" "unprognostic (2.82e-1)" "unprognostic (6.48e-3)" "unprognostic (1.00e-2)" "unprognostic (3.35e-1)" "prognostic unfavourable (4.66e-4)" "unprognostic (2.22e-2)" "unprognostic (3.68e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" 27.7 8.2 5.7 14.5 7.9 5.6 11.3 4.2 5.7 9.9 9.5 5.2 9.1 7.2 12.7 11.7 10.8 7.6 10.3 7.1 6.0 5.1 14.7 8.5 13.7 14.3 6.3 4.5 9.2 7.7 6.6 10.2 14.8 7.5 12.1 8.1 5.5 12.4 5.8 8.3 10.7 16.1 10.8 7.7 13.8 8.0 4.5 6.4 35.4 13.0 7.4 9.7 9.9 9.4 4.9 2.0 24.8 5.7 6.1 6.5 3.0 2.9 1.1 1.6 0.9 3.8 4.0 2.5 1.8 8.8 44.8 46.8 1.2 2.6 0.8 3.2 1.6 2.4 1.7 1.9 6.3 7.2 0.6 2.8 2.5 2.0 3.1 1.8 2.2 2.8 0.7 5.2 1.5 8.1 0.6 0.6 5.9 0.4 2.5 4.6 1.3 1.2 2.4 1.2 0.3 6.8 1.6 1.2 0.7 2.6 1.1 4.9 1.9 1.5 9.3 1.3 1.3 1.1 0.9 0.1 0.5 0.5 2.0 0.8 0.9 8.5 3.8 10.3 6.2 5.7 5.5 4.8 5.6 5.6 2.0 4.9 5.1 5.6 24.8 6.1 3.9 0.1 6.5 3.0 5.7 7.9 4.2 5.7 6.0 5.1 6.3 4.5 7.5 6.4 DDX59 "DKFZP564B1023, ZNHIT5" ENSG00000118197 "DEAD-box helicase 59" Q5T1V6 1 200623896-200669969 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Ciliopathy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047166 Approved Approved "Nucleoplasm,Actin filaments" "Nucleoplasm, Actin filaments" "HPA047166: AB_2679966" "unprognostic (1.99e-1)" "unprognostic (1.60e-1)" "unprognostic (3.44e-2)" "unprognostic (4.87e-2)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" "unprognostic (4.83e-2)" "unprognostic (3.40e-3)" "unprognostic (2.43e-3)" "unprognostic (4.16e-1)" "unprognostic (2.16e-1)" "prognostic unfavourable (9.02e-4)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (6.66e-2)" "unprognostic (5.98e-2)" 14.0 14.4 12.1 16.4 14.8 23.7 22.7 16.7 11.2 14.5 11.6 10.8 12.6 8.1 15.8 17.6 12.0 13.8 11.4 18.0 12.0 9.9 13.6 15.1 11.8 15.1 15.1 6.7 17.1 21.6 13.9 10.7 46.5 12.8 14.1 12.5 15.0 19.4 12.9 28.6 21.5 12.4 14.0 17.2 20.9 10.4 9.9 14.5 18.5 15.1 10.1 13.2 12.8 12.7 12.2 9.5 23.1 16.2 12.4 15.6 7.9 9.2 10.8 12.5 10.5 5.7 9.8 28.0 10.5 9.4 11.2 9.1 3.4 11.0 9.5 5.3 8.3 8.9 7.0 10.7 8.0 29.9 7.2 7.2 13.8 10.0 11.4 10.4 13.4 10.6 16.2 8.5 23.2 8.6 9.1 14.1 10.9 10.7 6.2 15.6 13.2 8.8 5.3 8.7 18.2 12.0 10.9 7.6 19.8 16.6 17.3 18.4 14.9 14.6 7.7 9.5 5.4 9.3 10.8 10.8 14.0 12.6 9.1 6.6 16.2 23.1 10.3 19.0 13.0 8.9 10.6 12.2 10.9 11.7 8.5 11.5 11.3 10.3 18.2 12.4 16.2 9.5 15.6 7.9 12.1 14.8 16.7 11.2 12.0 9.9 15.1 6.7 12.8 14.5 DDX6 "HLR2, RCK" ENSG00000110367 "DEAD-box helicase 6" P26196 11 118747766-118791149 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004668, HPA024201, HPA026644" Approved Supported "Cytosol,Cytoplasmic bodies" "Cytoplasmic bodies" Cytosol "CAB004668: AB_436960, HPA024201: AB_10603562, HPA026644: AB_1847582" "unprognostic (1.26e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-1)" "unprognostic (3.40e-2)" "unprognostic (4.12e-2)" "unprognostic (5.82e-2)" "prognostic unfavourable (6.56e-4)" "unprognostic (3.43e-1)" "unprognostic (1.48e-2)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (7.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.91e-3)" "unprognostic (1.88e-1)" "unprognostic (9.58e-2)" "unprognostic (4.55e-2)" 29.8 23.0 25.0 24.1 41.0 43.3 25.1 41.9 39.2 26.9 23.2 29.4 14.5 17.1 30.1 22.9 31.8 23.4 17.5 26.8 25.5 25.1 22.8 24.6 23.4 32.2 21.9 27.1 38.2 27.9 30.9 43.2 26.1 29.6 24.9 20.8 25.4 26.8 22.9 43.8 23.9 24.1 27.8 30.4 30.6 21.2 19.9 24.0 46.0 27.9 19.4 42.8 33.0 25.7 12.2 6.5 17.8 10.3 7.2 12.6 5.7 11.7 16.0 25.8 25.4 22.6 23.3 16.9 15.9 20.9 14.8 14.1 23.3 18.1 26.9 16.7 26.0 18.8 30.1 23.2 23.9 20.2 6.0 51.8 10.3 18.9 15.0 37.1 20.0 24.6 17.1 21.9 35.7 23.6 23.8 39.1 20.9 32.0 27.0 17.2 18.3 11.8 29.8 20.8 21.5 17.3 30.4 17.1 23.6 30.0 24.1 9.5 28.2 14.6 26.9 24.6 13.5 14.0 16.0 12.2 15.8 32.1 9.8 17.9 21.0 10.5 4.1 11.6 10.1 5.7 12.6 11.4 9.9 10.4 4.7 12.2 12.4 10.8 17.8 7.2 10.3 6.5 8.9 5.7 25.0 41.0 41.9 39.2 25.5 25.1 21.9 27.1 29.6 24.0 DDX60 FLJ20035 ENSG00000137628 "DExD/H-box helicase 60" Q8IY21 4 168216293-168318807 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 22.5;BJ hTERT+ SV40 Large T+ RasG12V: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA046952 Approved Supported "Intermediate filaments,Cytosol" Cytosol "Intermediate filaments" "HPA046952: AB_10963572" "unprognostic (4.05e-2)" "unprognostic (2.87e-1)" "unprognostic (7.22e-3)" "unprognostic (7.71e-2)" "unprognostic (2.30e-1)" "unprognostic (2.65e-2)" "unprognostic (1.50e-2)" "unprognostic (3.15e-2)" "unprognostic (3.06e-1)" "unprognostic (8.69e-3)" "prognostic unfavourable (3.35e-4)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (2.48e-1)" "unprognostic (3.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.44e-1)" 18.0 8.3 4.1 18.5 5.0 4.4 9.0 1.3 3.8 11.4 14.8 4.3 5.1 8.8 10.8 15.2 10.7 8.1 11.5 8.5 3.7 3.5 10.0 8.8 21.6 18.7 4.2 3.2 20.3 5.5 8.8 6.7 25.5 5.6 11.6 14.3 9.0 15.6 6.2 5.6 7.9 16.7 11.2 6.1 18.9 29.2 5.7 3.9 23.2 14.5 6.0 9.3 8.2 7.2 4.1 2.5 3.2 6.3 7.6 10.0 3.5 5.5 1.2 2.8 1.1 2.1 7.7 3.1 1.8 13.5 22.5 21.8 0.0 12.2 0.0 1.1 3.0 4.6 0.3 4.5 6.5 4.3 0.5 8.7 4.8 0.0 10.1 3.2 2.2 6.9 1.9 5.7 1.3 8.4 0.0 1.6 2.8 0.3 4.9 2.4 0.5 1.6 3.3 1.4 0.1 6.6 3.4 0.6 0.6 3.5 0.9 13.6 0.9 4.1 5.6 1.4 1.4 0.5 1.4 1.0 0.2 0.0 4.3 3.8 3.9 3.2 2.8 2.6 8.5 5.1 10.0 4.1 6.7 8.0 2.5 3.3 6.8 8.5 2.8 7.6 6.3 0.2 5.5 3.5 4.1 5.0 1.3 3.8 3.7 3.5 4.2 3.2 5.6 3.9 DDX60L FLJ31033 ENSG00000181381 "DExD/H-box 60 like" Q5H9U9 4 168356735-168537786 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 22.5" "Group enriched" "Detected in all" 4 "granulocytes: 22.5;monocytes: 7.8" "HPA043211, HPA055501" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA043211: AB_10794390, HPA055501: " "unprognostic (8.86e-2)" "unprognostic (2.77e-1)" "unprognostic (1.16e-1)" "unprognostic (2.45e-1)" "unprognostic (2.38e-1)" "unprognostic (3.20e-2)" "unprognostic (1.05e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (4.19e-2)" "prognostic unfavourable (3.04e-5)" "unprognostic (1.70e-1)" "prognostic unfavourable (2.94e-4)" "unprognostic (1.13e-1)" "unprognostic (8.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.69e-1)" 12.7 5.0 2.8 13.1 3.1 33.0 9.9 1.4 3.2 7.2 8.4 3.2 2.7 6.0 9.2 7.9 3.8 6.9 6.7 6.0 2.4 2.4 4.5 6.0 25.8 17.7 3.8 1.4 7.3 5.1 4.4 5.2 32.6 3.4 5.0 6.5 6.8 7.0 5.7 3.3 4.3 14.0 5.3 4.2 11.9 9.5 2.7 3.1 25.3 5.8 3.5 8.1 4.9 6.8 1.6 2.4 22.5 7.8 1.7 3.7 1.6 6.0 3.6 1.4 0.6 3.7 10.7 7.0 6.1 13.0 23.1 16.1 0.0 14.4 0.1 0.3 6.2 2.4 0.6 3.7 6.7 3.5 0.5 13.4 4.0 0.3 4.5 5.5 3.4 3.0 1.1 8.3 0.7 16.2 0.2 0.1 14.8 0.1 4.9 3.5 0.3 3.0 2.7 3.1 0.0 2.2 3.6 0.2 1.9 10.9 1.3 6.1 1.0 7.7 17.3 1.2 8.2 2.9 2.1 5.9 0.9 0.0 4.1 16.3 1.7 1.6 4.0 3.5 2.7 6.3 3.7 0.9 2.7 2.7 2.4 1.6 2.2 2.3 22.5 1.7 7.8 0.0 3.6 1.6 2.8 3.1 1.4 3.2 2.4 2.4 3.8 1.4 3.4 3.1 DECR1 "DECR, SDR18C1" ENSG00000104325 "2,4-dienoyl-CoA reductase 1" Q16698 8 90001405-90052092 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 120.2" "Cell line enriched" "Detected in many" 4 "SK-BR-3: 129.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023160, HPA023162, HPA023238" Enhanced Supported Mitochondria,Cytosol 740000 Mitochondria Cytosol "HPA023160: AB_1847585, HPA023162: AB_1847586, HPA023238: AB_1847587" "prognostic unfavourable (1.49e-4)" "unprognostic (5.76e-3)" "unprognostic (8.37e-3)" "unprognostic (6.13e-3)" "unprognostic (2.01e-1)" "unprognostic (4.45e-2)" "unprognostic (1.68e-2)" "unprognostic (8.23e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-1)" "unprognostic (9.12e-2)" "unprognostic (1.42e-1)" "prognostic favourable (1.79e-7)" "unprognostic (1.40e-1)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "prognostic favourable (6.06e-4)" 26.9 45.7 13.2 18.1 17.6 9.2 15.6 10.3 14.5 13.0 29.0 10.4 11.8 32.4 11.9 13.7 16.2 8.5 12.6 70.0 15.4 9.0 44.8 120.2 12.9 14.0 12.5 12.8 12.7 14.4 22.2 16.8 5.8 13.6 11.0 22.9 9.5 15.7 9.9 37.9 12.5 42.7 11.5 11.9 20.1 12.7 17.0 14.5 20.3 15.0 32.1 15.3 11.6 10.6 23.4 52.3 37.2 42.8 19.8 31.3 27.8 10.3 5.9 17.4 19.7 12.2 19.9 3.7 9.1 15.7 5.9 9.3 2.3 10.3 7.9 7.2 10.9 7.8 6.4 9.2 9.9 11.9 0.7 19.0 5.3 9.4 15.3 4.1 3.9 15.7 7.1 4.7 8.0 17.7 19.7 15.7 28.5 11.9 11.8 6.1 1.1 17.8 10.0 4.6 14.1 29.2 26.0 0.7 6.6 13.8 129.9 10.9 16.6 10.7 15.9 10.1 4.8 13.3 5.4 7.9 6.0 9.3 9.6 9.4 12.8 15.0 31.5 10.2 21.4 42.8 22.6 23.4 20.1 21.8 52.3 19.2 21.3 21.0 37.2 19.8 37.2 20.4 31.3 27.8 13.2 17.6 10.3 14.5 15.4 9.0 12.5 12.8 13.6 14.5 DECR2 "PDCR, SDR17C1" ENSG00000242612 "2,4-dienoyl-CoA reductase 2" Q9NUI1 16 401826-412487 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 68.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047631 Approved Peroxisomes Peroxisomes "HPA047631: " "unprognostic (2.74e-2)" "unprognostic (3.84e-1)" "unprognostic (1.83e-1)" "unprognostic (4.44e-3)" "unprognostic (1.77e-1)" "unprognostic (7.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (3.02e-2)" "unprognostic (3.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.12e-1)" "unprognostic (3.40e-1)" "unprognostic (2.21e-1)" "unprognostic (1.94e-1)" "unprognostic (4.22e-3)" 5.7 10.8 3.2 4.3 4.0 3.5 4.0 3.8 5.0 2.9 10.2 2.7 5.0 14.2 4.0 7.3 4.1 2.5 7.8 4.4 2.8 2.3 16.9 68.2 4.3 3.9 2.0 3.0 2.6 9.7 1.8 2.6 2.3 2.0 4.1 2.4 3.0 6.2 5.6 15.9 2.9 14.4 5.1 1.9 1.9 5.9 4.1 1.8 1.2 1.7 4.3 2.9 2.7 2.2 3.3 9.5 0.4 6.1 2.7 5.1 3.9 1.1 10.9 1.4 6.5 1.2 3.0 4.1 3.3 2.5 2.8 3.0 6.9 7.5 3.7 7.2 4.1 2.5 1.1 2.8 0.4 8.3 3.5 0.9 5.3 16.4 8.6 3.3 5.3 4.2 2.1 1.9 2.4 3.6 2.3 3.4 2.4 11.4 1.9 4.6 4.1 5.7 4.5 0.5 6.8 2.8 2.9 2.9 4.4 6.3 7.1 3.7 10.2 4.2 7.4 2.4 2.7 3.4 2.5 4.9 3.9 1.6 3.4 5.0 8.0 0.0 6.1 0.4 3.6 5.6 2.5 2.8 2.2 2.4 6.5 3.3 5.1 3.0 0.3 2.7 4.5 9.5 1.7 3.9 3.2 4.0 3.8 5.0 2.8 2.3 2.0 3.0 2.0 1.8 DEGS1 "DEGS-1, Des-1, DES1, FADS7, MLD" ENSG00000143753 "Delta 4-desaturase, sphingolipid 1" O15121 1 224175756-224193441 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 164.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076422 Supported Mitochondria Mitochondria "HPA076422: " "unprognostic (2.34e-2)" "unprognostic (6.91e-2)" "unprognostic (2.48e-2)" "prognostic unfavourable (7.74e-5)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "prognostic unfavourable (4.29e-5)" "unprognostic (7.70e-2)" "unprognostic (2.31e-1)" "unprognostic (3.20e-1)" "unprognostic (3.63e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (6.83e-7)" "unprognostic (2.87e-1)" "unprognostic (1.61e-1)" "unprognostic (3.86e-2)" "prognostic unfavourable (2.53e-4)" 19.2 10.7 14.7 14.1 15.7 20.0 28.6 11.9 17.8 17.8 17.0 19.9 15.8 15.0 17.2 13.4 16.1 13.1 13.5 16.6 15.1 16.4 12.8 17.3 16.1 24.5 22.0 17.4 14.4 9.3 11.8 15.1 40.1 17.9 27.6 9.4 15.9 14.8 20.1 7.6 164.4 12.1 23.3 22.1 13.0 14.6 9.2 19.3 7.7 19.7 12.3 15.7 15.5 24.9 31.7 39.5 43.6 25.7 16.1 24.4 16.8 14.8 10.5 13.9 10.2 60.2 38.9 10.7 41.5 46.7 29.2 35.0 9.6 11.4 11.8 54.0 37.5 15.7 16.1 14.1 32.4 17.2 28.7 8.5 11.5 5.8 36.6 17.0 18.4 38.7 31.6 26.8 15.1 28.7 12.5 13.0 37.3 5.4 8.6 9.2 17.2 15.5 7.9 19.6 7.6 37.0 4.0 9.0 14.5 22.1 34.8 21.9 11.8 24.8 26.1 28.0 8.9 32.2 40.4 9.3 11.0 10.8 30.2 8.5 31.4 32.3 22.3 43.6 12.7 25.7 24.4 23.9 21.5 17.5 39.5 31.7 17.1 15.0 26.1 16.1 17.4 13.2 22.0 16.8 14.7 15.7 11.9 17.8 15.1 16.4 22.0 17.4 17.9 19.3 DEGS2 "C14orf66, DES2, FADS8" ENSG00000168350 "Delta 4-desaturase, sphingolipid 2" Q6QHC5 14 100143957-100160163 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.5;skin 1: 30.6" "Cell line enriched" "Detected in some" 20 "T-47d: 48.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 22.9" "Cell type enhanced" "Detected in many" "memory B-cell: 11.9" "Group enriched" "Detected in many" 5 "B-cells: 11.9;granulocytes: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046644 Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA046644: " "unprognostic (8.18e-2)" "unprognostic (3.83e-3)" "unprognostic (2.33e-1)" "unprognostic (1.32e-2)" "unprognostic (3.55e-1)" "unprognostic (4.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (2.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "prognostic favourable (7.94e-7)" "unprognostic (1.03e-3)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "prognostic favourable (1.66e-4)" 0.4 0.3 2.0 2.3 4.6 0.5 5.8 22.9 6.4 5.3 20.2 1.8 0.6 20.8 3.4 4.6 20.9 1.9 13.3 0.3 2.0 1.5 8.7 17.2 2.6 0.8 2.4 1.4 0.8 13.0 0.3 1.6 0.6 2.7 2.5 4.2 0.8 4.5 2.3 0.5 30.6 44.5 0.7 1.9 0.5 17.9 0.7 0.7 0.0 2.4 7.3 11.1 7.1 5.2 11.9 0.7 6.4 0.5 0.2 1.8 0.8 0.0 0.1 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 1.8 0.1 0.1 0.0 0.0 0.1 0.0 1.6 0.0 0.7 2.4 0.0 0.0 1.4 0.0 48.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.7 0.5 6.4 1.8 0.0 0.0 11.9 0.1 0.8 0.7 5.9 0.0 1.2 0.2 0.2 0.0 0.1 0.0 0.8 2.0 4.6 22.9 6.4 2.0 1.5 2.4 1.4 2.7 0.7 DERA "CGI-26, DEOC" ENSG00000023697 "Deoxyribose-phosphate aldolase" Q9Y315 12 15911172-16037282 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055897 Supported Nucleoplasm 180000 Nucleoplasm "HPA055897: " "unprognostic (3.05e-1)" "unprognostic (1.26e-1)" "unprognostic (1.06e-2)" "unprognostic (7.26e-2)" "unprognostic (8.12e-2)" "unprognostic (7.74e-2)" "unprognostic (1.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.87e-1)" "prognostic unfavourable (1.32e-4)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (8.74e-2)" "unprognostic (2.17e-2)" "prognostic favourable (3.64e-5)" "unprognostic (3.66e-2)" 20.3 12.0 10.5 10.8 10.8 7.5 11.5 5.2 7.7 11.3 30.3 11.4 12.7 20.2 21.5 14.7 20.0 8.2 11.1 11.7 10.1 9.1 40.9 51.5 13.6 14.1 12.5 6.5 5.8 16.9 6.6 27.5 12.3 11.3 9.2 21.2 11.0 11.4 11.3 15.3 12.4 46.7 10.4 14.6 14.6 10.5 5.5 11.0 13.8 26.6 16.7 14.3 10.1 13.1 12.4 30.2 14.1 28.2 17.1 14.9 15.7 19.9 16.5 13.0 11.4 8.8 20.2 26.6 11.7 11.0 15.9 20.5 19.9 37.1 13.6 10.4 14.9 14.2 14.1 15.0 28.3 22.8 8.2 12.0 8.3 18.7 12.7 12.7 8.2 13.4 17.4 13.0 26.7 22.9 1.7 4.2 29.0 7.3 9.4 10.6 28.4 8.2 14.4 28.6 8.5 39.9 7.2 9.5 16.0 22.0 7.3 22.9 39.7 15.9 22.6 17.0 11.2 7.7 12.4 4.5 6.6 23.5 21.8 12.8 12.5 5.4 24.4 14.1 7.2 27.1 7.9 12.4 7.8 7.7 30.2 11.4 8.6 6.9 6.5 17.1 28.2 16.5 14.9 15.7 10.5 10.8 5.2 7.7 10.1 9.1 12.5 6.5 11.3 11.0 DESI2 "C1orf121, CGI-146, FAM152A, FLJ21998, PNAS-4, PPPDE1" ENSG00000121644 "Desumoylating isopeptidase 2" Q9BSY9 1 244652935-244709033 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049950 Approved Vesicles Vesicles "HPA049950: " "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (5.40e-2)" "unprognostic (1.95e-2)" "unprognostic (7.62e-2)" "unprognostic (1.38e-3)" "unprognostic (1.51e-1)" "unprognostic (4.47e-3)" "unprognostic (1.45e-1)" "prognostic unfavourable (4.25e-5)" "unprognostic (4.52e-2)" "unprognostic (8.27e-2)" "unprognostic (2.27e-2)" "unprognostic (9.49e-2)" 16.4 13.3 6.4 16.1 12.9 10.5 19.9 17.4 6.5 18.5 19.4 7.6 14.6 10.9 27.7 12.8 14.7 12.4 12.7 27.6 6.5 5.8 9.6 13.5 28.4 11.5 7.7 3.2 16.3 10.0 14.8 11.8 20.4 6.9 14.9 13.1 17.8 12.1 14.8 16.2 11.6 17.5 23.2 6.6 14.3 14.9 49.2 7.4 16.8 25.8 14.5 14.7 16.8 14.4 8.0 4.8 9.1 4.0 3.9 5.6 1.2 24.2 9.1 17.9 15.4 20.5 21.5 22.5 14.1 24.7 14.1 13.0 16.1 11.6 43.3 19.4 17.6 10.7 21.8 16.0 19.5 14.8 16.0 11.0 6.8 12.0 18.0 18.8 13.3 14.9 21.8 18.8 23.7 19.8 16.5 24.1 21.1 4.2 17.1 10.1 40.5 22.1 12.3 27.1 16.4 10.8 10.2 15.9 21.3 20.0 10.0 17.6 10.4 14.3 21.4 16.1 16.8 21.7 24.5 24.5 31.5 25.5 13.0 20.3 29.3 4.6 3.0 9.1 4.0 3.9 4.2 8.0 4.2 5.6 4.8 4.7 5.5 5.4 2.5 3.9 4.0 4.2 5.2 1.2 6.4 12.9 17.4 6.5 6.5 5.8 7.7 3.2 6.9 7.4 DGAT1 "ARGP1, DGAT" ENSG00000185000 "Diacylglycerol O-acyltransferase 1" O75907 8 144314584-144326910 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "intestine: 161.0" "Cell line enhanced" "Detected in many" "Hep G2: 15.8;PC-3: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032853 Enhanced Approved "Nucleoli,Endoplasmic reticulum" "Endoplasmic reticulum" Nucleoli "CAB032853: AB_2090798" "unprognostic (9.24e-3)" "unprognostic (1.61e-1)" "unprognostic (1.75e-2)" "unprognostic (2.23e-1)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (5.10e-2)" "unprognostic (2.78e-2)" "unprognostic (6.88e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-3)" "unprognostic (3.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.67e-3)" 11.8 18.5 3.6 5.7 4.7 6.4 6.8 6.6 5.6 3.3 60.2 4.0 6.4 44.7 3.9 3.6 5.5 3.1 7.9 6.3 3.7 2.7 6.7 14.4 3.8 3.1 4.1 2.7 3.3 3.9 5.0 4.0 4.3 3.6 3.4 6.3 4.1 5.9 4.3 10.0 4.8 161.0 3.6 2.6 5.3 5.7 10.7 4.2 5.1 3.8 6.2 5.0 4.7 3.4 0.7 2.2 2.8 2.0 0.3 1.7 0.8 3.8 4.1 1.9 3.6 3.2 1.3 2.3 2.7 2.7 2.6 1.8 9.7 2.6 1.5 10.6 1.7 3.3 1.6 3.7 0.5 2.8 4.0 2.8 3.3 15.8 2.3 0.7 2.9 1.8 2.9 1.6 1.9 2.0 2.2 3.5 1.7 3.2 4.8 3.1 0.9 17.6 6.2 0.8 2.5 2.4 2.1 2.0 3.4 3.6 4.4 1.8 2.5 2.7 1.6 1.4 4.9 2.8 2.2 2.0 0.4 0.6 1.4 4.9 2.3 0.0 2.0 2.8 1.2 1.3 1.7 0.7 0.9 1.1 2.2 0.5 0.7 0.3 2.3 0.3 1.7 1.1 0.7 0.8 3.6 4.7 6.6 5.6 3.7 2.7 4.1 2.7 3.6 4.2 DGKA "DAGK, DAGK1, DGK-alpha" ENSG00000065357 "Diacylglycerol kinase alpha" P23743 12 55927319-55954027 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.1" "Cell line enhanced" "Detected in many" "HBEC3-KT: 42.2;hTERT-HME1: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041645, HPA045462" Approved Approved Nucleoplasm,Vesicles,Mitochondria Vesicles "Nucleoplasm, Mitochondria" "HPA041645: , HPA045462: " "unprognostic (1.12e-3)" "unprognostic (1.43e-2)" "unprognostic (1.62e-2)" "unprognostic (2.63e-2)" "unprognostic (5.23e-2)" "unprognostic (2.04e-1)" "unprognostic (3.62e-1)" "unprognostic (3.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-2)" "unprognostic (2.46e-1)" "prognostic unfavourable (1.66e-5)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (1.47e-1)" "unprognostic (7.02e-2)" 4.9 4.7 7.1 31.8 8.2 9.7 4.8 6.0 10.8 8.4 13.4 3.6 3.1 20.5 6.9 4.1 42.0 4.9 7.9 3.8 4.6 2.4 3.9 1.5 7.6 28.6 2.1 4.1 4.9 6.4 6.2 3.1 10.2 3.3 10.6 11.0 4.1 16.2 5.3 1.0 33.0 27.2 5.7 3.7 23.1 4.8 4.4 2.6 117.1 4.5 9.6 57.0 13.0 15.1 7.6 4.0 5.4 2.8 5.2 30.2 10.9 6.7 4.3 3.0 4.0 7.5 9.8 0.9 15.2 15.6 6.0 4.4 2.0 11.5 3.8 3.6 10.1 12.4 3.2 42.2 7.2 3.2 0.7 6.1 9.1 1.1 6.5 1.9 6.0 8.4 22.7 8.3 44.8 12.2 0.7 5.9 16.1 0.7 12.5 2.4 0.6 5.1 5.8 1.0 0.6 14.2 19.5 0.5 1.7 5.0 0.2 0.5 2.7 2.0 10.9 3.9 2.8 0.8 0.5 0.7 0.3 9.2 4.7 5.2 1.1 5.2 2.8 5.4 6.5 2.0 11.7 7.6 24.3 11.7 4.0 6.4 30.2 18.1 5.2 5.2 1.2 4.0 26.7 10.9 7.1 8.2 6.0 10.8 4.6 2.4 2.1 4.1 3.3 2.6 DGKB "DAGK2, DGK, DGK-BETA, KIAA0718" ENSG00000136267 "Diacylglycerol kinase beta" Q9Y6T7 7 14145049-14974777 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 37.7" "Cell line enhanced" "Detected in some" "AF22: 2.7;fHDF/TERT166: 5.5;hTEC/SVTERT24-B: 2.1;SCLC-21H: 2.8;SH-SY5Y: 2.1;U-266/70: 7.4" "Cancer enriched" "Detected in single" 11 "glioma: 1.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020321 Supported "HPA020321: " "unprognostic (9.89e-2)" "unprognostic (9.72e-5)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (4.32e-2)" "unprognostic (3.37e-1)" "unprognostic (7.34e-2)" "unprognostic (5.91e-2)" "unprognostic (6.19e-2)" "unprognostic (8.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.18e-1)" "unprognostic (5.98e-2)" "unprognostic (2.37e-3)" "unprognostic (6.13e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-4)" 1.1 5.2 11.5 1.1 37.7 0.8 0.8 1.3 34.0 4.9 1.6 1.4 0.0 0.9 6.1 0.9 1.6 2.7 1.3 1.4 10.5 4.3 2.6 1.1 0.8 0.8 2.2 11.3 0.8 0.9 0.8 1.8 0.7 4.8 1.1 1.7 0.0 0.9 0.9 1.2 0.9 1.2 3.1 3.5 0.8 0.8 0.9 7.9 0.0 0.9 0.0 0.8 1.5 0.6 0.7 0.6 1.3 0.3 0.6 0.5 0.1 0.1 0.0 2.7 0.1 0.0 0.2 0.1 0.0 1.2 0.0 0.3 0.2 0.0 0.1 0.0 5.5 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 2.8 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 7.4 0.0 0.0 0.1 0.1 0.1 0.7 0.3 0.3 0.5 0.2 0.4 0.3 0.5 0.2 0.1 0.7 0.5 0.4 1.3 0.6 0.2 0.6 0.2 0.1 11.5 37.7 1.3 19.1 10.5 4.3 2.2 11.3 4.8 7.9 DGKD "DGKdelta, KIAA0145" ENSG00000077044 "Diacylglycerol kinase delta" Q16760 2 233354507-233472104 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 22.1;U-698: 22.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027530, HPA049101" Approved Supported Cytosol Cytosol "HPA027530: , HPA049101: " "unprognostic (1.84e-1)" "unprognostic (2.19e-2)" "unprognostic (7.76e-3)" "unprognostic (1.92e-2)" "unprognostic (5.69e-2)" "unprognostic (6.24e-2)" "prognostic unfavourable (1.69e-5)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (6.03e-2)" "unprognostic (5.76e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (4.07e-8)" "unprognostic (1.78e-1)" "unprognostic (7.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.94e-3)" 5.9 3.6 10.0 10.9 12.4 26.3 5.3 34.3 7.9 3.7 7.8 8.9 12.4 8.1 5.8 12.6 2.7 5.5 8.0 6.4 9.6 4.3 3.1 3.3 9.3 14.0 11.7 4.3 8.6 3.0 2.3 3.7 8.9 7.2 6.0 8.4 6.2 4.9 8.0 25.4 2.9 10.9 7.3 11.1 10.3 19.4 17.4 8.3 4.5 7.6 1.3 13.5 5.6 10.1 6.6 1.0 5.9 2.0 1.8 3.4 2.5 3.2 8.0 4.7 3.0 2.2 2.2 7.2 1.9 1.7 1.8 1.9 13.8 3.2 5.8 1.0 3.0 3.2 5.1 2.3 3.0 8.7 4.8 8.1 22.1 4.7 2.8 7.0 8.8 3.1 4.9 2.3 4.4 2.0 5.7 1.3 1.9 3.1 5.7 7.3 2.5 4.5 11.4 8.7 4.7 1.4 3.8 7.2 5.2 6.5 3.5 3.4 1.5 12.5 1.9 3.9 7.2 2.3 5.8 4.7 2.9 22.4 3.4 10.9 3.0 1.7 2.0 5.9 3.3 0.8 1.6 6.3 1.0 2.9 1.0 6.6 2.3 3.4 2.0 1.8 1.4 0.6 0.5 2.5 10.0 12.4 34.3 7.9 9.6 4.3 11.7 4.3 7.2 8.3 DGKE "DAGK6, DGK" ENSG00000153933 "Diacylglycerol kinase epsilon" P52429 17 56834099-56869567 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 42.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017167 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA017167: AB_1847638" "unprognostic (1.19e-2)" "unprognostic (2.11e-2)" "unprognostic (2.69e-1)" "prognostic favourable (3.92e-5)" "unprognostic (4.20e-2)" "unprognostic (4.87e-2)" "unprognostic (3.37e-1)" "unprognostic (4.27e-2)" "unprognostic (1.19e-3)" "unprognostic (4.75e-2)" "unprognostic (6.07e-3)" "unprognostic (2.68e-1)" "unprognostic (2.55e-2)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-1)" "unprognostic (3.69e-3)" 7.8 4.9 7.8 8.3 17.7 5.5 5.2 21.3 18.6 9.5 7.4 4.4 5.6 5.4 13.3 8.9 5.0 8.2 9.4 4.9 7.4 9.2 4.2 4.9 8.1 9.3 5.6 10.0 7.3 6.5 9.5 14.5 5.5 9.9 8.9 7.0 17.4 4.3 7.3 2.4 3.4 7.1 9.3 6.8 12.7 6.4 12.5 5.4 14.5 8.3 2.5 8.6 6.5 15.3 2.4 2.4 1.2 0.8 1.9 4.5 0.8 1.6 1.6 1.5 0.1 0.2 0.5 0.7 2.8 2.3 1.9 2.3 3.7 2.0 2.4 3.5 1.5 2.0 3.6 1.5 4.0 7.8 4.6 3.1 3.9 2.4 1.7 6.0 4.5 0.9 2.0 2.0 4.1 2.6 2.5 42.7 2.4 2.4 14.2 3.4 1.1 4.8 4.4 6.2 5.8 1.9 3.7 2.3 1.6 2.3 1.2 0.1 2.6 2.9 2.4 0.5 2.7 0.8 0.4 5.6 11.5 1.6 1.7 3.5 0.1 0.3 0.5 0.0 2.7 0.4 2.0 2.4 1.9 2.3 0.6 0.9 1.9 2.5 1.2 1.9 0.8 2.4 4.5 0.8 7.8 17.7 21.3 18.6 7.4 9.2 5.6 10.0 9.9 5.4 DGKG DAGK3 ENSG00000058866 "Diacylglycerol kinase gamma" P49619 3 186105668-186362237 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.4" "Cell line enhanced" "Detected in some" "HDLM-2: 19.8;HL-60: 6.3;U-266/84: 7.5;U-87 MG: 12.5;U-937: 5.9" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 4.2;eosinophil: 2.4;intermediate monocyte: 2.4;myeloid DC: 2.9;neutrophil: 5.3;non-classical monocyte: 2.8" "Group enriched" "Detected in many" 6 "dendritic cells: 2.9;granulocytes: 5.3;monocytes: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036577 Approved Approved "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "HPA036577: AB_10672358" "unprognostic (2.23e-1)" "unprognostic (1.97e-1)" "unprognostic (1.56e-2)" "unprognostic (3.24e-5)" "unprognostic (2.70e-1)" "unprognostic (6.09e-4)" "unprognostic (1.21e-3)" "unprognostic (3.80e-2)" "unprognostic (5.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.94e-1)" "unprognostic (5.09e-2)" "unprognostic (8.05e-7)" "unprognostic (3.47e-3)" "unprognostic (7.19e-2)" "unprognostic (1.41e-1)" "unprognostic (9.16e-3)" 3.1 6.9 13.4 3.1 7.1 14.5 1.9 53.4 23.1 2.7 3.5 6.2 1.1 3.0 1.9 14.6 8.5 7.7 2.2 15.0 15.3 7.4 3.1 2.1 4.3 2.1 7.4 11.3 2.0 1.6 4.7 7.5 13.5 25.2 3.1 2.1 7.8 1.9 4.0 2.4 1.4 2.7 5.3 5.6 2.0 3.3 1.2 7.1 0.0 2.5 0.0 2.1 4.8 2.4 0.6 2.9 5.3 4.2 0.0 0.0 1.3 2.6 4.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 2.3 0.0 0.2 0.0 0.0 0.0 19.8 0.0 2.6 0.0 2.9 0.0 6.3 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.3 0.1 0.1 2.2 0.4 1.2 1.4 0.0 2.2 0.0 0.0 0.5 0.0 0.8 0.0 1.6 0.1 4.1 0.0 0.0 0.7 2.0 2.4 0.0 7.5 0.0 12.5 5.9 2.3 0.0 4.2 2.4 0.0 2.4 0.0 0.6 0.0 0.0 2.9 0.3 0.0 0.0 5.3 0.0 2.8 0.5 0.0 1.3 13.4 7.1 53.4 14.7 15.3 7.4 7.4 11.3 25.2 7.1 DGKH DGKeta ENSG00000102780 "Diacylglycerol kinase eta" Q86XP1 13 42040036-42256578 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039533, HPA040355" Uncertain "HPA039533: AB_10795145, HPA040355: AB_10796452" "unprognostic (2.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.30e-1)" "unprognostic (5.69e-2)" "unprognostic (1.55e-3)" "unprognostic (7.62e-2)" "unprognostic (1.04e-2)" "unprognostic (9.60e-2)" "unprognostic (7.00e-3)" "unprognostic (4.37e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (3.43e-3)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (4.93e-2)" "unprognostic (1.43e-2)" 4.9 2.8 3.3 4.9 12.7 2.3 8.3 9.6 6.2 5.2 6.4 3.4 7.9 3.1 9.4 14.0 5.2 5.9 6.8 10.2 9.0 2.7 6.0 6.8 9.5 4.0 3.5 4.0 4.3 4.2 1.4 3.5 8.9 3.6 4.6 6.9 5.5 7.7 4.8 5.8 6.2 5.1 8.3 3.5 6.1 4.0 7.0 4.3 2.2 4.3 2.0 2.9 8.1 6.0 1.4 1.5 4.3 1.3 0.7 1.7 0.2 4.9 5.7 4.7 3.7 1.8 4.0 0.5 3.2 2.4 2.0 2.6 0.5 4.2 3.8 3.9 3.3 10.8 4.0 7.0 3.2 3.2 11.3 6.9 3.0 0.4 2.3 2.8 1.9 1.5 7.1 3.9 16.1 9.2 2.7 2.6 3.5 4.7 2.9 1.6 1.9 3.9 4.6 3.8 2.6 6.9 14.7 2.7 2.5 2.9 3.7 2.7 3.3 8.1 9.0 4.0 3.5 4.2 4.2 1.4 1.3 4.4 2.1 2.6 2.8 2.4 1.3 0.6 1.1 0.9 1.2 0.8 1.7 1.7 0.3 1.4 1.0 1.6 4.3 0.7 0.7 1.5 1.1 0.2 3.3 12.7 9.6 6.2 9.0 2.7 3.5 4.0 3.6 4.3 DGKQ "DAGK, DAGK4, DAGK7" ENSG00000145214 "Diacylglycerol kinase theta" P52824 4 958887-986895 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026797, CAB033835" Uncertain "CAB033835: AB_2091307, HPA026797: AB_10600902" "unprognostic (7.39e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.64e-2)" "unprognostic (1.14e-1)" "unprognostic (5.08e-2)" "unprognostic (3.37e-1)" "unprognostic (6.39e-2)" "unprognostic (2.90e-2)" "unprognostic (1.06e-1)" "unprognostic (6.45e-2)" "unprognostic (1.06e-2)" "unprognostic (9.77e-2)" "unprognostic (3.08e-3)" "unprognostic (4.38e-2)" "unprognostic (2.65e-2)" "unprognostic (1.65e-3)" 6.4 9.3 15.9 10.7 13.8 10.4 6.9 21.6 17.4 5.4 14.7 7.9 6.9 27.0 6.3 3.8 7.9 5.3 10.3 4.5 15.0 12.1 8.4 8.9 6.9 12.3 9.7 12.3 5.1 9.8 5.5 8.2 4.4 10.2 7.0 8.4 6.7 12.1 5.8 3.7 13.0 28.0 5.9 5.2 12.7 8.6 6.8 7.7 9.1 6.7 3.8 8.7 6.6 7.0 1.3 1.9 4.0 1.4 5.3 5.0 1.8 4.2 6.8 3.0 10.1 3.6 3.0 11.2 8.1 4.6 4.6 4.6 4.9 8.4 5.7 6.8 5.1 4.9 1.7 5.6 1.1 4.4 5.3 8.7 6.3 8.5 6.3 3.7 11.7 5.7 9.6 3.8 1.8 5.6 6.6 0.7 3.5 6.3 7.7 21.7 5.3 11.7 12.5 0.9 0.6 5.0 5.9 1.9 5.1 2.8 3.2 8.4 7.5 9.2 8.1 8.0 3.8 9.0 5.3 15.6 6.6 4.3 6.9 8.1 7.2 4.0 1.4 2.9 5.0 1.1 2.3 1.1 1.8 4.1 0.9 1.3 1.9 3.4 0.9 5.3 1.1 1.9 1.1 1.8 15.9 13.8 21.6 17.4 15.0 12.1 9.7 12.3 10.2 7.7 DGKZ "DAGK5, DAGK6, DGK-ZETA, hDGKzeta" ENSG00000149091 "Diacylglycerol kinase zeta" Q13574 11 46332905-46380554 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051336 Enhanced Supported "Nuclear speckles" "Nuclear speckles" "HPA051336: " "unprognostic (2.85e-2)" "unprognostic (3.90e-2)" "unprognostic (2.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.40e-1)" "unprognostic (4.12e-2)" "unprognostic (3.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (2.49e-2)" "unprognostic (3.66e-3)" "unprognostic (8.18e-2)" "prognostic unfavourable (4.74e-5)" "unprognostic (1.48e-3)" "unprognostic (7.75e-2)" "unprognostic (3.61e-2)" "unprognostic (7.84e-3)" 8.6 6.7 34.5 11.8 27.4 28.0 6.8 22.6 50.7 7.5 7.4 8.5 2.5 21.0 6.1 4.3 7.1 6.3 6.7 16.0 48.0 9.2 5.3 3.3 8.3 20.7 9.4 26.7 5.0 17.3 7.0 18.6 8.4 7.5 5.9 4.2 4.8 24.1 7.0 42.8 8.3 23.2 5.6 7.2 15.6 9.9 5.0 7.5 14.2 4.1 9.1 9.9 7.6 5.0 0.9 12.3 11.2 11.8 7.7 7.5 8.1 11.7 10.5 7.1 10.7 3.8 4.2 33.2 9.2 6.9 9.8 8.6 12.5 5.5 15.1 6.7 9.5 13.7 8.6 13.3 3.5 15.1 20.0 9.9 7.7 9.1 6.8 18.6 19.9 5.7 6.3 5.3 7.3 10.7 13.8 9.4 6.9 31.0 17.9 29.2 20.8 16.2 21.4 12.4 6.4 3.0 11.6 49.0 8.3 10.5 35.3 7.2 25.4 23.5 12.0 12.9 14.0 20.3 16.5 6.2 7.0 12.4 17.6 16.9 11.9 11.2 11.8 5.8 7.5 6.1 4.5 0.4 4.7 6.3 12.3 0.9 4.9 5.0 9.8 7.7 5.9 5.9 4.5 8.1 34.5 27.4 22.6 50.7 48.0 9.2 9.4 26.7 7.5 7.5 DGLUCY "C14orf159, FLJ39975" ENSG00000133943 "D-glutamate cyclase" Q7Z3D6 14 91060333-91225632 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 82.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 57.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041423, HPA052932" Approved Supported Cytosol Cytosol "HPA041423: AB_10795540, HPA052932: " "unprognostic (5.02e-2)" "unprognostic (1.01e-2)" "unprognostic (1.56e-1)" "prognostic favourable (4.28e-4)" "unprognostic (1.28e-1)" "unprognostic (2.26e-1)" "unprognostic (3.58e-2)" "prognostic favourable (9.48e-5)" "unprognostic (3.56e-1)" "prognostic favourable (7.28e-4)" "unprognostic (2.30e-1)" "unprognostic (1.74e-1)" "prognostic favourable (3.77e-15)" "unprognostic (1.50e-1)" "unprognostic (9.51e-2)" "unprognostic (2.75e-2)" "unprognostic (2.57e-3)" 12.5 18.7 23.4 15.9 23.1 10.7 9.3 27.3 22.6 14.6 16.7 18.1 16.0 13.8 16.8 13.1 16.0 21.9 12.5 63.9 18.8 16.6 20.1 13.1 13.7 11.2 20.1 19.2 13.4 9.3 29.3 14.2 9.2 19.0 13.3 17.0 11.3 17.4 22.3 82.9 13.9 12.3 20.0 18.5 17.3 18.9 12.2 21.6 11.2 16.8 29.1 14.1 19.4 11.4 9.4 19.8 57.9 19.3 5.6 12.0 7.0 2.7 7.4 3.8 9.1 15.5 14.7 9.9 2.8 8.0 8.9 9.2 4.8 21.4 18.5 21.5 8.5 8.2 10.4 11.3 3.7 10.2 4.3 12.4 3.7 6.1 22.8 12.6 18.1 22.6 4.9 4.9 1.9 15.8 6.2 25.3 8.4 0.7 9.9 12.0 7.6 0.7 17.1 7.4 13.4 15.1 11.7 10.5 5.3 4.8 8.3 3.4 14.7 10.7 11.3 2.7 2.3 8.0 2.6 14.5 10.3 6.2 13.9 16.6 1.7 13.7 13.6 8.1 8.8 19.3 9.0 9.4 5.9 7.2 19.8 7.0 4.9 6.0 57.9 5.6 15.5 6.2 12.0 7.0 23.4 23.1 27.3 22.6 18.8 16.6 20.1 19.2 19.0 21.6 DGUOK dGK ENSG00000114956 "Deoxyguanosine kinase" Q16854 2 73926826-73958961 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034766, HPA057246" Approved "HPA034766: AB_10669850, HPA057246: " "unprognostic (3.40e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-2)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (4.17e-2)" "unprognostic (2.14e-2)" "unprognostic (1.37e-2)" "unprognostic (4.10e-3)" "unprognostic (5.07e-2)" "unprognostic (1.41e-1)" "unprognostic (9.84e-2)" "prognostic unfavourable (8.69e-7)" "unprognostic (3.86e-1)" "unprognostic (2.21e-2)" "unprognostic (5.98e-2)" "prognostic favourable (7.47e-4)" 23.8 34.8 25.8 26.2 32.3 26.3 33.7 18.4 33.7 26.1 28.0 23.6 24.9 19.4 30.7 40.9 26.6 35.4 28.0 24.5 28.3 26.5 26.7 31.7 24.7 37.2 23.5 22.6 35.5 20.9 11.2 39.9 30.6 27.1 28.6 34.1 25.2 22.5 28.2 14.1 29.2 29.3 25.8 23.5 33.1 23.6 34.3 17.9 41.7 29.0 21.8 44.2 27.2 27.4 43.5 36.4 50.5 31.4 30.0 42.3 31.3 15.7 26.9 27.9 24.8 18.1 19.9 13.7 10.5 21.2 25.4 23.6 34.0 19.1 29.8 10.1 15.5 12.5 31.7 20.5 30.5 16.3 19.1 23.4 10.2 38.4 26.7 21.4 23.8 18.7 19.4 18.6 21.9 17.9 23.8 13.7 29.1 19.2 20.1 37.8 28.3 19.7 25.9 28.0 19.8 20.2 18.4 32.1 31.4 10.3 10.1 27.1 12.2 12.2 16.8 16.3 26.2 14.1 19.0 11.2 10.8 30.0 23.5 23.2 34.6 41.3 27.4 50.5 25.3 31.4 29.8 40.6 31.4 27.9 32.4 43.5 42.3 33.1 22.5 30.0 30.8 36.4 29.3 31.3 25.8 32.3 18.4 33.7 28.3 26.5 23.5 22.6 27.1 17.9 DHCR24 "DCE, KIAA0018, seladin-1" ENSG00000116133 "24-dehydrocholesterol reductase" Q15392 1 54849633-54887218 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 164.5;liver: 119.6" "Cell line enhanced" "Detected in many" "ASC diff: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017981, CAB037247, HPA063005" Enhanced "CAB037247: AB_796187, HPA017981: , HPA063005: AB_2684919" "unprognostic (2.88e-1)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "prognostic unfavourable (1.05e-5)" "unprognostic (1.69e-1)" "unprognostic (2.61e-1)" "unprognostic (1.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.68e-1)" "unprognostic (1.86e-1)" "unprognostic (6.18e-3)" "unprognostic (3.35e-1)" "unprognostic (7.82e-3)" "unprognostic (5.48e-2)" "unprognostic (1.83e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-2)" 10.6 164.5 6.6 3.9 22.1 0.7 22.0 6.5 27.5 7.7 11.1 43.8 1.2 11.9 2.2 1.1 40.8 12.3 8.6 3.7 12.0 9.2 6.4 119.6 40.9 2.0 36.2 13.0 7.8 4.6 28.4 2.6 4.4 47.9 26.1 8.3 4.8 20.2 2.1 24.6 47.6 7.3 2.7 71.7 24.3 17.6 14.1 31.1 1.7 4.3 17.1 14.3 2.5 13.0 5.4 7.0 7.3 3.1 3.7 9.0 5.5 39.9 7.4 26.1 31.5 131.0 28.2 6.1 11.5 20.0 16.7 34.4 41.0 25.3 6.4 23.3 10.1 38.4 31.3 60.9 14.9 0.9 19.6 35.6 17.4 49.0 21.3 14.8 8.3 20.5 53.1 51.5 9.5 8.1 25.9 0.0 6.1 16.8 3.1 13.0 72.3 20.2 0.0 6.6 19.7 91.6 32.5 18.0 6.6 21.9 41.4 15.1 53.9 17.3 7.5 5.6 16.2 8.0 21.8 2.8 6.3 11.0 4.0 25.5 7.2 7.3 2.4 1.1 9.0 3.1 0.5 5.4 4.0 4.2 7.0 2.4 3.9 4.7 0.1 3.7 1.0 4.2 0.7 5.5 6.6 22.1 6.5 27.5 12.0 9.2 36.2 13.0 47.9 31.1 DHCR7 SLOS ENSG00000172893 "7-dehydrocholesterol reductase" Q9UBM7 11 71428193-71452868 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 64.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044280 Approved Supported "Endoplasmic reticulum,Cytosol" "Endoplasmic reticulum" Cytosol "HPA044280: AB_10794893" "unprognostic (1.76e-1)" "unprognostic (1.50e-3)" "unprognostic (1.32e-2)" "unprognostic (7.16e-3)" "unprognostic (2.69e-1)" "unprognostic (2.18e-3)" "unprognostic (8.57e-3)" "unprognostic (3.02e-2)" "unprognostic (4.91e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-2)" "unprognostic (5.45e-2)" "prognostic favourable (6.93e-7)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "prognostic unfavourable (5.67e-4)" 8.0 40.1 12.1 5.6 14.5 19.0 16.8 5.3 22.8 5.5 9.3 27.9 8.8 20.8 4.0 27.3 14.6 5.2 5.8 10.7 13.7 13.2 7.1 64.8 12.0 2.7 20.6 12.3 21.5 7.3 14.0 7.0 3.7 23.4 10.0 6.6 16.6 10.0 3.9 5.4 22.9 15.8 4.5 20.5 5.9 8.5 17.7 15.5 2.8 5.4 12.1 7.7 4.3 7.4 6.3 6.2 3.5 1.9 4.6 12.1 5.7 21.6 19.6 19.2 21.2 9.0 14.0 6.0 8.9 23.8 7.6 20.8 73.0 71.1 15.1 14.3 8.5 41.6 22.8 48.3 8.1 5.7 17.1 5.7 16.6 31.2 23.1 10.8 2.8 16.2 21.4 28.6 19.7 11.2 27.0 32.3 7.6 58.1 8.9 12.2 27.5 11.7 8.1 27.0 65.0 28.6 32.7 26.1 9.7 8.5 28.2 20.3 27.3 5.9 10.6 2.1 11.6 0.6 10.7 10.7 12.9 16.1 6.1 19.2 8.6 3.5 1.9 1.7 9.7 1.2 11.8 6.3 8.2 9.0 2.5 5.4 10.5 12.1 1.0 4.6 1.2 6.2 5.1 5.7 12.1 14.5 5.3 22.8 13.7 13.2 20.6 12.3 23.4 15.5 DHDDS "DS, FLJ13102, HDS, RP59" ENSG00000117682 "Dehydrodolichyl diphosphate synthase subunit" Q86SQ9 1 26432282-26471294 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease mutation, Epilepsy, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026721, HPA026727" Uncertain Uncertain "Plasma membrane" "Plasma membrane" "HPA026721: AB_1847643, HPA026727: AB_1847644" "unprognostic (1.11e-2)" "unprognostic (5.43e-2)" "unprognostic (5.12e-2)" "unprognostic (9.81e-2)" "unprognostic (6.71e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-3)" "unprognostic (3.81e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-2)" "unprognostic (4.51e-2)" "unprognostic (3.40e-2)" "prognostic favourable (4.08e-7)" "unprognostic (9.42e-2)" "unprognostic (2.85e-1)" "unprognostic (2.22e-1)" "unprognostic (2.95e-1)" 31.8 14.4 11.2 10.8 15.9 6.4 15.0 45.9 18.8 10.4 23.1 12.5 8.3 12.2 15.4 21.9 18.9 9.2 10.9 14.8 9.7 10.7 16.2 15.3 9.5 10.3 12.1 15.8 9.8 14.7 23.2 15.5 13.1 20.6 9.6 23.9 22.0 56.9 9.1 10.3 13.1 12.2 11.3 7.6 10.5 14.2 12.9 8.9 9.7 12.1 11.1 16.9 10.6 9.8 11.1 11.2 11.8 19.5 8.1 11.6 8.2 14.7 12.0 8.0 11.0 16.5 13.9 13.8 25.2 15.7 19.5 19.5 18.5 16.2 16.7 15.4 23.5 10.8 10.8 19.7 18.7 10.2 5.7 16.5 29.9 13.6 15.6 18.0 24.4 19.0 11.8 26.9 15.1 24.6 11.8 18.4 17.9 10.1 9.2 7.6 12.6 16.1 11.0 14.2 14.2 10.6 13.9 11.3 9.0 17.0 18.7 11.1 14.1 10.2 31.2 13.6 13.2 25.5 14.3 22.3 29.9 18.0 21.4 22.7 13.2 6.5 13.4 7.1 11.6 19.5 8.4 11.1 7.7 7.5 11.2 9.3 6.5 9.0 11.8 8.1 18.0 9.1 7.3 8.2 11.2 15.9 45.9 18.8 9.7 10.7 12.1 15.8 20.6 8.9 DHDH HUM2DD ENSG00000104808 "Dihydrodiol dehydrogenase" Q9UQ10 19 48933682-48944969 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 32.4;kidney: 18.0" "Cell line enhanced" "Detected in many" "U-266/70: 6.7;U-266/84: 5.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 5.8;naive CD4 T-cell: 4.8" "Group enriched" "Detected in many" 31 "granulocytes: 5.8;T-cells: 4.8" "Low region specificity" "Detected in all" HPA044131 Approved Approved "Nucleoplasm,Actin filaments" "Nucleoplasm, Actin filaments" "HPA044131: AB_10966968" "unprognostic (1.54e-1)" "unprognostic (2.72e-2)" "unprognostic (1.07e-1)" "prognostic unfavourable (9.91e-4)" "unprognostic (3.33e-3)" "unprognostic (1.45e-1)" "unprognostic (5.81e-6)" "unprognostic (1.56e-2)" "unprognostic (5.88e-2)" "unprognostic (4.96e-2)" "unprognostic (3.30e-2)" "unprognostic (5.08e-2)" "prognostic favourable (3.15e-4)" "unprognostic (2.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.54e-1)" 0.3 0.5 1.5 0.1 2.1 0.1 0.2 1.8 1.5 0.1 8.2 0.2 0.1 10.6 0.2 0.4 0.8 0.3 0.8 0.1 2.7 2.0 18.0 0.7 1.9 0.2 0.4 0.4 0.5 0.4 0.2 2.1 1.3 0.6 3.5 0.1 1.2 0.8 0.2 0.3 0.2 32.4 0.1 0.9 1.8 0.7 2.8 0.1 0.4 0.1 0.5 0.7 1.1 0.3 0.1 0.0 5.8 0.0 0.0 4.8 0.5 2.9 0.0 0.2 1.5 0.8 0.7 1.2 0.0 0.4 0.5 1.4 2.8 2.3 0.0 0.6 0.0 0.8 1.0 2.1 1.0 1.1 2.3 4.1 0.9 1.1 0.0 0.0 1.0 0.6 0.2 1.1 0.0 0.0 1.3 0.4 0.0 0.6 0.0 0.3 0.6 1.9 1.5 0.2 2.1 0.4 0.9 4.5 2.4 0.5 0.3 0.9 2.0 0.1 0.0 0.0 1.8 0.7 0.1 6.7 5.3 1.7 1.4 0.0 0.4 5.8 0.0 0.9 1.6 0.0 0.8 0.0 1.6 0.7 0.0 0.1 4.8 3.1 0.1 0.0 0.0 0.0 1.2 0.5 1.5 2.1 1.8 1.5 2.7 2.0 0.4 0.4 0.6 0.1 DHFR ENSG00000228716 "Dihydrofolate reductase" P00374 5 80626228-80654983 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Methotrexate resistance, One-carbon metabolism" "Oxidoreductase, RNA-binding" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB037129, HPA051465" Uncertain Supported Mitochondria Mitochondria "CAB037129: AB_439683, HPA051465: " "unprognostic (1.44e-2)" "unprognostic (1.03e-2)" "unprognostic (2.24e-3)" "unprognostic (2.91e-3)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (2.83e-2)" "unprognostic (2.35e-2)" "unprognostic (2.02e-2)" "unprognostic (4.19e-3)" "unprognostic (1.83e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (1.82e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" 17.7 6.1 16.0 11.6 13.9 28.3 10.9 10.2 14.0 7.5 12.6 18.1 11.7 14.5 5.9 9.0 9.8 4.7 6.9 9.7 17.3 14.4 13.1 35.5 8.6 23.2 18.9 9.4 7.5 4.9 9.6 7.2 8.5 13.0 5.9 15.5 8.6 8.0 8.4 10.4 5.9 14.5 7.3 25.3 9.1 7.4 10.5 11.5 13.4 9.2 2.3 22.8 7.9 6.1 2.4 3.3 3.5 2.6 2.1 4.0 2.1 19.6 13.6 34.6 25.6 6.6 6.9 12.7 15.7 12.1 27.4 31.7 12.9 23.7 39.8 6.9 9.1 13.8 44.4 20.3 44.4 17.6 27.4 19.1 22.6 12.0 1.4 22.2 8.5 4.8 2.1 24.5 2.7 13.2 21.4 30.6 27.7 19.7 54.7 9.0 17.4 8.0 35.5 67.9 39.4 15.7 12.5 28.3 19.8 22.2 10.4 11.2 20.5 22.0 7.9 8.7 13.2 24.3 30.0 14.4 28.8 43.1 19.4 45.2 22.3 0.8 1.2 1.1 2.3 2.6 1.1 2.1 2.7 3.2 1.9 2.4 2.1 2.7 3.5 2.1 1.7 3.3 4.0 2.1 16.0 13.9 10.2 14.0 17.3 14.4 18.9 9.4 13.0 11.5 DHFR2 "DHFRL1, DHFRP4, FLJ16119" ENSG00000178700 "Dihydrofolate reductase 2" Q86XF0 3 94047836-94063389 "Enzymes, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA051465 Uncertain Supported Mitochondria Mitochondria "HPA051465: " "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-2)" "unprognostic (3.50e-2)" "unprognostic (2.07e-1)" "unprognostic (1.38e-1)" "unprognostic (5.92e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (4.62e-2)" "unprognostic (2.95e-1)" "unprognostic (1.52e-1)" "prognostic favourable (2.30e-6)" "unprognostic (1.63e-1)" "unprognostic (1.79e-1)" "unprognostic (1.13e-1)" "unprognostic (2.96e-2)" 6.6 8.0 9.7 5.2 10.9 2.2 7.7 5.2 13.2 9.8 6.3 15.2 2.8 5.8 11.7 9.9 5.3 9.4 7.6 5.1 9.8 8.1 10.6 9.3 7.1 7.3 10.2 6.9 15.3 10.8 15.4 13.1 4.5 12.2 9.5 6.7 6.2 6.6 8.9 2.8 5.8 10.1 9.0 12.6 9.4 6.6 8.2 8.6 16.9 10.3 4.8 6.4 7.3 6.2 5.0 4.1 3.8 3.3 2.8 7.3 2.5 4.2 6.6 5.1 5.1 7.0 8.9 2.0 6.6 7.2 3.3 3.8 1.3 7.0 2.8 4.5 3.5 5.9 3.8 4.6 5.2 9.4 2.1 3.5 3.1 3.7 7.2 2.3 4.1 9.0 6.3 3.9 5.1 3.4 1.8 6.5 4.3 5.1 12.0 1.4 4.1 8.1 3.1 6.6 4.6 4.6 2.2 6.3 6.4 9.5 2.5 10.7 6.5 3.5 5.3 5.3 8.9 2.1 2.4 4.8 4.8 4.0 5.2 6.1 7.1 3.6 2.2 3.8 3.8 3.2 7.3 3.8 5.1 6.1 1.4 5.0 6.9 6.2 3.5 2.8 3.3 4.1 6.1 2.5 9.7 10.9 5.2 13.2 9.8 8.1 10.2 6.9 12.2 8.6 DHODH ENSG00000102967 "Dihydroorotate dehydrogenase (quinone)" Q02127 16 72008588-72027664 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Pyrimidine biosynthesis" Oxidoreductase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 72.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010123, HPA011942" Approved Enhanced Nucleoplasm,Mitochondria,Cytosol Mitochondria "Nucleoplasm, Cytosol" "HPA010123: AB_1847648, HPA011942: AB_1847649" "unprognostic (4.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-2)" "unprognostic (1.41e-3)" "unprognostic (2.10e-1)" "unprognostic (4.27e-2)" "unprognostic (1.31e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-1)" "unprognostic (2.14e-1)" "unprognostic (6.40e-2)" "unprognostic (9.26e-3)" "unprognostic (1.98e-1)" "unprognostic (1.97e-1)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" 5.9 4.2 4.7 8.8 5.1 2.9 5.0 2.7 5.0 5.9 4.4 6.1 1.4 3.4 6.6 2.3 5.1 5.2 2.3 11.5 4.3 3.0 6.6 72.4 3.4 5.5 4.8 2.7 6.2 9.9 7.1 4.0 2.6 5.2 3.9 4.8 5.9 6.0 4.4 11.7 4.0 3.0 7.5 4.0 3.5 3.4 4.3 5.4 4.0 3.6 7.1 5.1 3.5 3.3 11.2 13.4 3.9 8.1 9.3 12.9 6.8 7.3 15.4 4.5 7.4 2.4 3.2 8.5 6.3 2.5 9.6 7.4 12.1 6.8 16.6 8.6 3.4 7.8 8.8 6.8 11.3 3.7 8.3 9.1 7.5 11.8 6.8 12.6 6.7 3.1 7.0 11.6 12.2 6.9 13.9 3.0 5.8 19.6 11.9 12.1 10.1 6.0 15.1 5.9 17.5 5.8 4.9 5.3 6.3 8.5 9.1 4.1 8.1 6.4 3.0 8.8 5.5 8.3 9.2 5.8 10.8 28.1 4.6 13.8 8.0 3.9 8.1 0.9 9.3 7.7 12.7 11.2 8.9 9.0 13.3 10.6 12.4 12.9 2.1 9.3 5.6 13.4 7.1 6.8 4.7 5.1 2.7 5.0 4.3 3.0 4.8 2.7 5.2 5.4 DHPS MIG13 ENSG00000095059 "Deoxyhypusine synthase" P49366 19 12675717-12681902 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hypusine biosynthesis" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014461, HPA029413" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "HPA014461: AB_1847651, HPA029413: AB_10602217" "unprognostic (4.17e-2)" "unprognostic (2.55e-2)" "unprognostic (2.05e-2)" "unprognostic (2.61e-1)" "unprognostic (3.10e-1)" "unprognostic (1.01e-2)" "unprognostic (3.06e-1)" "unprognostic (2.42e-1)" "unprognostic (1.85e-1)" "unprognostic (3.59e-2)" "unprognostic (1.20e-2)" "unprognostic (4.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.46e-3)" "unprognostic (1.32e-1)" "unprognostic (1.56e-1)" "unprognostic (8.83e-2)" 16.4 30.3 26.9 18.6 31.2 17.0 24.8 43.3 38.8 20.7 25.7 27.5 25.3 23.1 20.9 16.9 21.3 32.3 18.2 26.0 26.3 28.0 23.4 30.3 18.9 24.2 27.5 28.0 34.8 32.0 28.8 32.6 23.2 22.4 24.1 24.5 20.2 24.8 24.6 65.1 25.6 21.5 24.5 29.1 19.5 24.2 13.3 26.3 31.9 24.9 22.9 26.9 23.5 19.2 39.6 29.5 35.8 30.5 27.8 38.1 29.7 20.7 15.3 24.9 13.2 11.2 18.5 5.8 13.3 19.6 25.5 25.7 10.9 10.1 21.5 15.1 14.5 12.6 17.0 18.9 17.6 18.8 12.0 14.3 16.7 14.3 13.8 17.1 22.9 14.9 23.3 15.4 26.6 17.8 13.0 15.3 18.6 41.2 30.5 24.8 19.5 26.1 20.3 9.3 31.0 19.6 11.2 32.4 44.0 13.4 19.5 22.6 18.1 28.7 8.9 30.0 12.2 29.3 20.2 48.9 52.7 14.6 18.4 21.1 28.3 14.5 27.0 35.8 24.7 24.2 25.9 39.6 28.9 25.6 29.0 36.9 38.1 28.1 9.7 27.8 30.5 29.5 34.3 29.7 26.9 31.2 43.3 38.8 26.3 28.0 27.5 28.0 22.4 26.3 DHRS11 "MGC4172, SDR24C1" ENSG00000278535 "Dehydrogenase/reductase 11" Q6UWP2 17 36591798-36600806 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "intestine: 88.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041226, HPA048236, HPA053623" Enhanced Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" 11000 Cytosol "Golgi apparatus" "HPA041226: , HPA048236: , HPA053623: " "unprognostic (2.00e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.80e-2)" "unprognostic (3.67e-1)" "unprognostic (5.94e-2)" "unprognostic (1.33e-2)" "unprognostic (4.11e-2)" "prognostic favourable (3.24e-4)" "unprognostic (1.45e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" 1.3 0.6 1.2 4.1 2.4 0.4 0.7 0.5 5.7 0.4 38.7 0.4 0.4 42.7 0.4 0.1 1.2 1.1 1.4 2.0 0.5 2.5 1.7 0.1 0.0 0.0 2.4 0.1 2.8 1.5 0.2 0.0 1.6 0.5 12.4 2.8 2.1 0.8 2.0 0.8 88.0 0.9 0.1 0.0 1.1 2.2 0.3 0.0 1.3 1.3 1.0 0.4 0.0 0.9 0.2 0.9 0.7 0.1 2.7 0.1 6.5 5.9 2.8 7.4 0.6 1.7 5.5 2.0 1.4 6.4 5.8 9.6 5.3 0.7 1.4 2.0 6.9 6.0 4.1 6.5 3.4 11.4 1.7 5.7 18.6 3.1 1.9 0.6 0.9 3.9 4.4 3.3 4.9 15.6 5.8 3.5 5.8 6.4 3.5 2.2 2.3 8.0 7.0 11.0 6.5 5.6 6.0 2.6 7.0 7.3 16.4 10.0 1.8 1.8 0.9 9.1 4.8 5.0 9.5 8.0 2.3 3.3 4.7 2.8 0.4 0.5 0.9 1.0 0.7 0.1 0.4 1.0 0.6 0.1 0.9 1.3 0.9 0.5 0.1 0.1 0.2 2.7 0.1 DHRS3 "RDH17, retSDR1, Rsdr1, SDR1, SDR16C1" ENSG00000162496 "Dehydrogenase/reductase 3" O75911 1 12567910-12617731 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 29.0;CAPAN-2: 59.3;SK-BR-3: 31.8;WM-115: 55.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "gdT-cell: 33.5;MAIT T-cell: 24.2;memory CD4 T-cell: 18.3;memory CD8 T-cell: 15.7;myeloid DC: 8.6;naive CD4 T-cell: 31.6;naive CD8 T-cell: 19.7;NK-cell: 13.8" "Group enriched" "Detected in many" 9 "dendritic cells: 8.6;NK-cells: 13.8;T-cells: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010844 Supported Approved Nucleoli,Mitochondria "Nucleoli, Mitochondria" "HPA010844: AB_1847653" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-2)" "unprognostic (1.74e-3)" "unprognostic (1.87e-1)" "unprognostic (3.68e-2)" "unprognostic (2.25e-3)" "unprognostic (5.06e-2)" "unprognostic (3.40e-2)" "unprognostic (5.18e-2)" "unprognostic (1.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.80e-1)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "prognostic favourable (2.65e-4)" "unprognostic (5.48e-2)" 22.7 4.4 6.3 6.2 8.6 2.5 30.6 4.0 7.9 16.7 16.3 3.4 9.2 13.6 7.6 15.5 19.0 12.2 11.2 16.1 6.8 8.6 12.3 45.6 11.6 8.3 9.0 4.5 11.8 20.3 0.5 8.9 11.5 9.8 16.3 5.6 20.3 11.8 14.3 10.2 5.6 18.9 11.1 9.8 4.2 12.3 5.2 4.2 3.1 40.5 5.4 5.2 21.0 9.4 0.2 8.6 2.1 0.3 13.8 33.5 15.6 5.1 29.0 0.0 12.8 16.8 1.4 3.3 1.7 0.0 0.0 0.1 3.4 59.3 0.0 1.4 17.0 23.4 6.2 3.2 0.0 0.0 10.4 4.5 3.0 16.1 2.5 0.0 0.0 8.5 3.9 0.1 0.1 5.4 6.8 0.0 0.1 0.9 1.2 0.2 1.9 11.7 0.1 0.0 5.9 0.0 9.9 0.3 0.5 9.8 31.8 1.8 3.1 1.2 3.9 0.1 0.6 8.9 0.1 0.9 0.0 0.0 6.7 0.4 55.1 2.1 0.2 0.0 33.5 0.1 24.2 0.2 18.3 15.7 8.6 0.2 31.6 19.7 1.7 13.8 0.3 1.0 0.5 15.6 6.3 8.6 4.0 7.9 6.8 8.6 9.0 4.5 9.8 4.2 DHRS4 "FLJ11008, humNRDR, SCAD-SRL, SDR-SRL, SDR25C2" ENSG00000157326 "Dehydrogenase/reductase 4" Q9BTZ2 14 23953586-23969279 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA023972 Uncertain Approved "Nuclear membrane,Vesicles" Vesicles "Nuclear membrane" "HPA023972: AB_1854890" "unprognostic (1.21e-2)" "unprognostic (2.59e-1)" "unprognostic (3.46e-2)" "unprognostic (3.79e-3)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (7.35e-3)" "unprognostic (1.61e-3)" "unprognostic (2.66e-1)" "unprognostic (1.19e-2)" "unprognostic (1.06e-2)" "unprognostic (7.65e-2)" "prognostic favourable (4.55e-6)" "unprognostic (2.03e-2)" "unprognostic (1.48e-1)" "unprognostic (2.03e-1)" "unprognostic (5.68e-2)" 15.8 18.5 8.3 10.3 13.7 5.9 15.4 4.4 9.6 11.0 22.2 10.2 12.1 30.3 13.7 11.7 17.2 8.3 16.3 16.3 9.0 6.6 65.8 40.3 12.6 13.6 14.0 7.7 12.6 20.6 7.3 9.7 8.9 9.3 17.0 12.4 12.0 17.5 14.4 25.3 16.6 35.2 14.4 9.6 12.4 12.9 13.5 12.6 6.9 17.1 16.1 11.1 10.0 14.8 9.7 22.0 2.6 25.5 7.9 10.6 14.9 7.5 15.5 5.3 8.7 8.5 9.4 0.1 14.4 7.6 5.7 4.6 3.2 8.2 6.5 7.7 7.1 9.1 4.3 5.9 5.2 17.5 8.8 3.9 13.0 18.1 5.2 5.6 24.2 9.4 7.4 4.8 10.4 7.1 5.8 15.5 7.8 26.0 10.3 5.3 5.2 15.6 16.7 9.4 21.5 5.9 8.9 10.3 8.7 13.8 9.0 6.8 8.3 7.6 13.2 7.1 7.5 7.3 4.6 11.9 11.1 1.7 6.2 6.4 7.1 2.4 25.5 2.6 8.9 21.0 10.6 9.7 10.1 8.9 22.0 8.3 10.3 9.9 1.1 7.9 11.1 18.5 8.6 14.9 8.3 13.7 4.4 9.6 9.0 6.6 14.0 7.7 9.3 12.6 DHTKD1 "CMT2Q, DKFZP762M115, KIAA1630, MGC3090" ENSG00000181192 "Dehydrogenase E1 and transketolase domain containing 1" Q96HY7 10 12068972-12123225 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Oxidoreductase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.5" "Cell line enhanced" "Detected in all" "T-47d: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037949, HPA037950, HPA066098" Approved Supported Mitochondria Mitochondria "HPA037949: , HPA037950: AB_10673650, HPA066098: " "unprognostic (3.76e-2)" "unprognostic (8.08e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (3.04e-3)" "unprognostic (3.83e-3)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (3.02e-3)" "unprognostic (3.46e-1)" "unprognostic (1.56e-1)" "prognostic favourable (3.43e-4)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-2)" "unprognostic (2.88e-3)" 5.7 6.3 6.5 4.7 6.6 2.2 5.0 5.7 7.2 5.5 5.7 9.8 5.0 4.5 4.7 5.0 5.1 4.2 4.5 7.7 5.3 4.8 23.8 69.5 4.2 6.9 7.5 5.2 7.1 16.6 5.4 4.1 4.7 6.2 7.6 6.3 7.2 9.7 7.1 10.5 3.6 4.3 3.5 6.1 5.1 6.1 4.4 6.6 10.1 6.8 6.7 8.0 5.2 4.1 9.5 12.5 16.8 11.0 10.2 4.1 3.3 11.2 8.7 13.0 10.3 8.1 4.8 15.7 5.7 3.7 10.2 9.1 5.5 6.7 8.1 1.9 3.5 16.1 13.6 4.4 11.7 4.5 6.1 4.4 3.4 4.2 7.9 1.7 1.7 5.9 3.5 5.9 2.4 5.5 6.9 6.6 2.7 21.8 5.9 3.2 7.2 2.0 10.1 4.2 6.8 6.6 2.7 3.4 15.3 11.2 20.1 6.7 44.2 6.4 2.4 3.3 2.4 6.9 4.1 5.9 4.1 5.2 4.3 3.1 5.5 16.8 4.8 10.7 3.2 6.8 3.4 9.5 2.5 2.1 8.6 7.8 2.5 3.3 14.0 10.2 11.0 12.5 4.1 3.3 6.5 6.6 5.7 7.2 5.3 4.8 7.5 5.2 6.2 6.6 DHX15 "DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p" ENSG00000109606 "DEAH-box helicase 15" O43143 4 24517441-24584550 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047047 Approved Enhanced "Nuclear speckles" 30000 "Nuclear speckles" "HPA047047: " "unprognostic (4.46e-3)" "unprognostic (2.47e-2)" "prognostic favourable (5.74e-4)" "unprognostic (3.35e-1)" "unprognostic (5.30e-2)" "unprognostic (5.74e-2)" "unprognostic (2.06e-3)" "unprognostic (5.53e-3)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (8.68e-3)" "unprognostic (7.77e-3)" "unprognostic (2.51e-3)" "unprognostic (2.19e-1)" "unprognostic (1.59e-1)" "unprognostic (5.41e-3)" 34.3 29.6 23.2 32.1 27.5 42.5 33.0 38.0 27.6 31.1 31.9 29.5 24.1 22.8 37.5 23.4 40.8 30.6 22.9 32.6 22.8 18.8 30.0 29.5 31.2 34.7 29.4 17.7 36.5 35.9 42.5 32.8 39.2 27.4 28.2 37.7 22.4 34.1 24.9 36.5 36.0 30.7 30.7 22.8 32.4 32.4 21.0 27.9 58.3 33.5 31.6 43.0 35.4 35.7 20.3 26.7 31.4 24.1 24.5 28.8 17.7 29.6 29.1 48.3 23.9 23.7 23.2 28.8 34.6 30.5 36.6 36.4 29.5 36.0 54.5 21.4 28.3 24.9 62.0 41.6 57.0 20.0 29.4 47.3 31.9 23.8 14.0 48.7 32.7 19.4 25.1 35.6 24.1 30.5 44.3 22.1 41.4 22.4 63.8 32.6 52.5 26.5 42.1 56.7 25.5 43.6 42.7 41.5 26.0 26.8 25.9 24.3 28.3 25.3 27.8 31.0 20.4 23.4 40.3 16.7 28.1 65.2 20.8 39.8 36.9 31.4 20.2 18.8 21.1 20.6 28.8 19.9 23.6 24.5 26.7 20.3 24.9 23.7 9.7 24.5 24.1 17.8 25.8 17.7 23.2 27.5 38.0 27.6 22.8 18.8 29.4 17.7 27.4 27.9 DHX16 "DBP2, DDX16, Prp2, PRPF2" ENSG00000204560 "DEAH-box helicase 16" O60231 6 30653119-30673037 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051455 Supported Supported Nucleoplasm Nucleoplasm "HPA051455: " "unprognostic (7.04e-2)" "unprognostic (1.37e-1)" "unprognostic (7.29e-2)" "unprognostic (7.46e-2)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (4.36e-3)" "unprognostic (1.13e-1)" "unprognostic (2.66e-2)" "unprognostic (3.11e-1)" "unprognostic (8.58e-2)" "unprognostic (1.24e-2)" "unprognostic (9.77e-3)" "unprognostic (4.42e-2)" "unprognostic (1.51e-1)" "unprognostic (2.64e-1)" "unprognostic (8.73e-3)" 12.8 15.8 12.7 16.8 14.0 12.1 14.4 16.8 14.9 13.3 16.2 12.3 15.8 19.3 16.3 13.3 14.9 14.4 14.6 12.4 11.4 7.1 18.0 19.2 13.9 18.2 13.6 8.6 15.6 19.1 24.3 16.6 11.3 13.5 16.4 13.6 14.4 18.0 18.2 23.2 18.4 19.8 16.4 11.0 22.6 14.9 36.8 14.9 18.8 21.6 12.1 16.5 13.2 15.3 4.5 5.9 8.7 7.6 7.1 5.8 4.4 9.6 4.0 5.9 9.2 6.8 4.6 7.1 8.0 6.4 11.6 9.0 9.1 4.0 7.3 7.5 7.1 9.3 9.7 7.2 9.3 10.3 8.0 7.2 7.4 5.1 5.9 18.2 9.7 4.2 7.1 9.4 8.1 3.5 12.0 7.2 5.7 8.0 5.2 9.2 5.6 5.6 8.7 6.3 7.9 6.1 7.6 7.1 5.7 8.9 9.4 6.5 7.2 5.5 3.8 7.5 5.1 7.2 11.7 8.6 13.3 7.2 3.6 10.0 9.5 6.0 6.0 8.7 5.8 7.5 5.3 4.4 5.3 4.8 5.9 4.5 4.4 5.0 5.8 7.1 7.6 4.8 5.1 4.4 12.7 14.0 16.8 14.9 11.4 7.1 13.6 8.6 13.5 14.9 DHX29 DDX29 ENSG00000067248 "DExH-box helicase 29" Q7Z478 5 55256245-55307722 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Helicase, Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038317, HPA038318" Approved Approved Cytosol "Intracellular and membrane" Cytosol "HPA038317: AB_10673169, HPA038318: AB_10672589" "unprognostic (3.43e-2)" "unprognostic (5.09e-1)" "unprognostic (2.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (2.37e-3)" "unprognostic (1.72e-1)" "unprognostic (6.66e-2)" "unprognostic (1.76e-2)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.57e-3)" "unprognostic (4.01e-1)" "unprognostic (3.85e-1)" "unprognostic (4.78e-3)" "unprognostic (9.40e-2)" 14.6 16.2 15.1 12.2 16.6 9.8 16.3 22.0 16.9 17.3 18.4 9.2 20.2 11.3 17.4 12.8 18.5 13.6 11.7 22.1 12.8 9.6 22.4 20.6 15.2 11.8 13.7 11.9 13.8 15.3 30.3 30.7 17.7 16.3 18.9 13.3 7.8 15.2 24.3 31.8 15.9 14.7 18.5 13.1 14.3 14.8 10.2 16.6 15.6 20.9 12.0 11.9 19.9 14.4 18.5 25.9 32.4 19.6 16.0 18.8 6.3 22.2 15.7 13.1 17.3 21.6 18.2 16.1 23.8 18.8 17.5 18.2 12.8 14.6 13.0 21.7 26.7 16.5 20.6 23.1 25.2 5.3 11.6 12.0 14.6 8.9 12.4 8.0 12.8 15.9 14.3 18.7 11.3 23.0 14.6 10.0 20.9 15.4 14.0 8.0 11.1 17.6 6.8 20.6 21.5 15.2 15.4 12.2 8.3 23.6 13.0 11.8 18.4 14.8 20.1 16.1 13.6 14.4 17.3 9.6 14.4 17.7 19.8 13.9 18.1 32.4 16.3 15.9 13.5 16.4 15.1 18.5 16.9 15.0 12.1 17.6 18.8 15.8 15.2 16.0 19.6 25.9 13.9 6.3 15.1 16.6 22.0 16.9 12.8 9.6 13.7 11.9 16.3 16.6 DHX30 "DDX30, FLJ11214, KIAA0890" ENSG00000132153 "DExH-box helicase 30" Q7L2E3 3 47802909-47850195 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034806 Supported Supported Mitochondria,Cytosol Mitochondria Cytosol "HPA034806: AB_10601364" "unprognostic (2.00e-1)" "unprognostic (8.37e-2)" "unprognostic (3.27e-1)" "unprognostic (2.14e-2)" "unprognostic (3.04e-1)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "prognostic favourable (1.37e-6)" "unprognostic (4.12e-2)" "unprognostic (1.43e-1)" "unprognostic (2.81e-1)" "unprognostic (2.22e-1)" 18.4 18.7 22.1 18.5 31.1 23.6 18.3 31.2 43.5 22.3 17.8 26.9 15.5 17.3 23.3 14.8 21.0 24.8 17.9 21.3 19.1 19.8 18.6 19.3 16.7 22.0 20.4 28.0 27.1 21.2 37.3 24.8 20.6 23.6 20.4 13.0 22.0 20.4 23.6 27.1 26.2 16.1 18.8 15.3 21.2 18.7 54.4 18.4 23.8 20.1 15.2 16.9 18.6 17.6 9.9 13.0 9.8 10.5 8.2 16.1 11.6 8.1 20.7 20.5 21.1 9.5 7.9 14.0 15.4 13.2 26.6 19.2 23.8 17.4 26.5 12.1 15.0 12.5 30.3 21.5 9.5 18.0 36.3 23.1 30.5 23.2 16.5 21.5 24.0 13.8 13.7 28.1 19.8 17.3 32.5 17.1 12.4 22.0 27.3 23.6 22.8 35.4 18.2 11.0 23.5 13.3 20.7 16.9 22.5 15.0 21.4 11.1 15.0 22.6 12.0 16.1 20.9 18.1 28.2 20.7 25.8 24.1 16.7 18.8 19.9 9.8 10.1 7.2 15.0 10.3 13.0 9.9 12.7 16.1 13.0 9.3 12.1 13.0 1.5 8.2 10.5 7.8 14.3 11.6 22.1 31.1 31.2 43.5 19.1 19.8 20.4 28.0 23.6 18.4 DHX32 "DDX32, DHLP1, FLJ10694, FLJ10889" ENSG00000089876 "DEAH-box helicase 32 (putative)" Q7L7V1 10 125836337-125896436 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048872 Approved "HPA048872: " "unprognostic (1.05e-1)" "unprognostic (3.02e-1)" "unprognostic (3.97e-2)" "unprognostic (6.40e-2)" "unprognostic (2.40e-1)" "unprognostic (3.57e-1)" "unprognostic (1.55e-2)" "unprognostic (9.88e-2)" "unprognostic (2.85e-1)" "unprognostic (6.89e-3)" "prognostic unfavourable (9.49e-5)" "prognostic unfavourable (6.34e-4)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (8.62e-2)" "unprognostic (1.98e-1)" "unprognostic (2.49e-1)" 15.4 16.3 7.8 10.2 9.7 4.0 18.0 7.3 11.5 10.5 20.1 12.1 11.2 11.4 10.6 14.0 20.6 8.6 13.1 27.3 7.6 7.5 12.1 14.5 10.1 16.8 10.3 7.0 18.1 23.5 11.7 9.5 19.3 8.9 13.1 24.5 12.8 17.9 8.4 16.0 18.5 16.1 9.1 9.8 12.2 21.7 20.6 9.5 8.0 13.6 10.7 10.0 13.0 12.6 6.8 2.3 3.2 3.5 4.5 5.3 0.9 27.1 15.0 10.1 20.8 13.6 12.5 18.2 12.1 28.0 11.0 12.4 3.5 27.0 0.1 9.1 14.0 19.9 4.6 20.3 9.2 13.7 9.0 3.3 7.7 5.3 15.0 6.5 11.2 12.3 21.3 10.8 24.4 16.0 9.3 0.1 10.6 12.2 0.1 10.4 7.7 10.4 0.1 16.5 5.9 16.0 12.7 1.4 7.4 11.2 20.1 16.5 7.4 5.8 14.3 8.6 5.3 10.9 10.6 10.8 10.4 0.2 15.6 0.1 4.4 0.3 3.0 3.2 2.7 3.5 2.2 6.8 1.3 1.1 2.3 3.2 5.3 2.1 0.1 4.5 1.7 1.3 0.4 0.9 7.8 9.7 7.3 11.5 7.6 7.5 10.3 7.0 8.9 9.5 DHX33 "DDX33, DKFZp762F2011, FLJ21972" ENSG00000005100 "DEAH-box helicase 33" Q9H6R0 17 5440912-5469060 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073875 Supported Supported Nucleoli Nucleoli "HPA073875: " "unprognostic (4.96e-2)" "unprognostic (1.35e-1)" "unprognostic (3.41e-2)" "unprognostic (2.51e-2)" "unprognostic (9.24e-2)" "unprognostic (1.90e-1)" "unprognostic (1.49e-2)" "unprognostic (6.15e-2)" "unprognostic (3.11e-2)" "unprognostic (3.80e-1)" "unprognostic (2.10e-1)" "prognostic unfavourable (6.10e-4)" "unprognostic (1.03e-1)" "unprognostic (4.66e-1)" "unprognostic (3.55e-1)" "unprognostic (4.69e-2)" "unprognostic (3.37e-2)" 10.0 10.4 11.6 11.0 14.6 7.0 12.9 15.8 22.0 9.0 8.7 14.1 8.6 8.6 12.4 7.9 11.2 11.2 9.2 7.7 9.7 7.0 8.2 13.4 8.0 10.1 11.0 13.2 11.1 12.1 16.5 7.3 11.5 10.3 10.0 10.7 11.3 10.4 10.8 13.9 12.5 8.7 11.1 8.0 11.1 9.6 10.1 11.7 8.4 9.5 9.4 10.3 9.6 9.5 3.7 3.4 2.6 3.5 3.0 2.5 0.7 10.3 15.3 9.8 17.5 4.1 8.4 12.2 10.2 6.4 15.8 12.8 9.6 4.5 25.3 7.2 8.4 12.3 19.9 16.0 20.2 8.1 19.1 10.0 12.5 16.2 8.2 13.4 9.1 7.0 9.8 16.8 23.1 11.7 13.3 12.6 8.6 7.3 13.5 7.3 21.7 7.8 18.2 14.4 13.7 7.2 8.0 8.6 12.4 10.7 9.2 15.8 7.2 7.0 10.8 10.9 11.5 8.6 21.6 4.7 5.0 13.0 7.8 16.0 15.6 0.6 3.5 1.8 2.2 1.4 2.1 2.5 2.5 1.4 1.4 3.7 2.5 2.4 2.6 3.0 1.3 3.4 1.8 0.7 11.6 14.6 15.8 22.0 9.7 7.0 11.0 13.2 10.3 11.7 DHX34 "DDX34, KIAA0134" ENSG00000134815 "DExH-box helicase 34" Q14147 19 47349281-47382704 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "neutrophil: 13.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 13.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042159, HPA043558" Uncertain Uncertain "Nucleoplasm,Intermediate filaments" "Nucleoplasm, Intermediate filaments" "HPA042159: AB_10963066, HPA043558: AB_10961262" "unprognostic (1.26e-1)" "unprognostic (5.17e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (1.08e-1)" "unprognostic (3.06e-3)" "prognostic unfavourable (8.63e-6)" "unprognostic (9.14e-2)" "unprognostic (4.74e-2)" "unprognostic (5.11e-2)" "unprognostic (4.76e-3)" "unprognostic (2.02e-2)" "prognostic unfavourable (3.16e-6)" "unprognostic (7.38e-2)" "unprognostic (1.59e-1)" "unprognostic (2.72e-1)" "unprognostic (7.21e-3)" 6.8 6.9 12.6 11.0 11.5 20.3 6.6 18.7 13.3 8.2 5.9 9.1 8.9 7.7 10.4 5.3 8.3 9.0 5.7 6.0 11.2 6.4 7.2 10.9 8.9 7.9 12.3 8.4 13.3 12.9 7.8 14.2 7.8 11.4 8.9 4.6 8.5 9.9 8.3 7.8 11.8 7.0 6.6 10.5 13.5 6.7 21.8 12.5 5.6 9.6 4.6 9.6 7.3 11.2 1.5 1.9 13.5 2.2 0.8 1.8 1.1 7.1 18.8 4.6 9.1 4.1 2.8 8.8 5.7 1.9 5.9 5.3 12.0 7.0 11.0 5.8 3.2 10.5 6.4 7.5 3.0 9.1 17.4 11.5 10.2 9.1 4.5 8.9 4.9 3.5 6.1 10.0 5.6 3.9 19.1 4.8 3.9 8.4 8.8 22.2 9.6 11.3 9.7 3.7 6.6 3.2 9.7 8.3 5.1 7.0 7.0 4.6 6.3 5.7 4.4 6.9 9.0 4.3 10.0 7.3 10.0 10.3 5.6 6.5 8.1 1.0 2.0 0.8 1.3 2.2 1.2 1.2 1.0 1.8 1.9 1.5 1.6 0.7 13.5 0.8 1.7 1.5 0.6 1.1 12.6 11.5 18.7 13.3 11.2 6.4 12.3 8.4 11.4 12.5 DHX35 "C20orf15, DDX35, FLJ22759, KAIA0875" ENSG00000101452 "DEAH-box helicase 35" Q9H5Z1 20 38962299-39039723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054451, HPA062700" Uncertain Approved "Nucleoplasm,Nuclear bodies,Centrosome" "Nuclear bodies" "Nucleoplasm, Centrosome" "HPA054451: , HPA062700: " "unprognostic (8.31e-2)" "unprognostic (2.34e-2)" "unprognostic (5.51e-2)" "prognostic unfavourable (4.25e-5)" "unprognostic (1.29e-2)" "unprognostic (8.38e-2)" "prognostic unfavourable (5.63e-6)" "unprognostic (9.83e-2)" "unprognostic (2.21e-1)" "unprognostic (6.22e-2)" "unprognostic (4.47e-2)" "unprognostic (5.67e-2)" "unprognostic (8.57e-2)" "unprognostic (1.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (3.31e-1)" 10.4 7.3 9.7 6.9 14.6 13.9 9.8 9.7 14.3 12.2 23.2 14.8 10.7 9.9 19.7 13.9 13.9 12.5 9.2 16.9 9.0 5.8 10.4 7.5 8.7 12.6 8.2 6.7 13.9 6.5 12.1 13.5 8.4 10.9 13.3 14.3 12.4 10.4 12.6 12.5 11.1 12.4 14.7 9.9 8.4 13.4 12.5 9.4 12.1 8.5 7.6 11.2 15.9 11.8 4.6 6.7 2.0 4.9 5.8 8.2 4.4 7.3 4.4 11.9 4.9 4.6 6.0 8.4 4.4 7.8 10.1 7.8 21.0 7.2 8.4 7.8 8.4 11.7 8.2 12.9 10.1 2.1 4.0 11.2 10.0 11.9 5.5 13.0 5.9 7.0 8.3 8.9 8.4 4.5 11.3 4.8 5.4 6.0 21.3 10.0 6.8 9.9 10.4 17.4 6.8 3.7 8.4 10.5 8.2 12.1 7.3 11.1 9.9 10.8 4.4 14.6 8.0 5.7 9.1 4.8 6.4 8.8 8.6 5.9 7.6 0.0 4.9 2.0 5.3 4.5 5.2 4.6 4.5 5.6 6.7 4.3 8.2 4.3 1.0 5.8 3.8 2.4 2.8 4.4 9.7 14.6 9.7 14.3 9.0 5.8 8.2 6.7 10.9 9.4 DHX36 "DDX36, KIAA1488, MLEL1" ENSG00000174953 "DEAH-box helicase 36" Q9H2U1 3 154272546-154324497 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Differentiation, Immunity, Innate immunity, Transcription, Transcription regulation, Translation regulation, Transport" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035399 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA035399: AB_10670115" "unprognostic (8.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.86e-1)" "unprognostic (3.50e-3)" "unprognostic (2.67e-2)" "unprognostic (3.22e-1)" "unprognostic (8.80e-3)" "unprognostic (1.03e-1)" "unprognostic (7.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.94e-2)" "unprognostic (3.90e-2)" "unprognostic (2.72e-1)" "unprognostic (5.09e-2)" "unprognostic (5.27e-1)" "unprognostic (4.96e-2)" "unprognostic (1.37e-1)" 16.3 14.0 11.5 14.1 27.5 12.6 15.7 19.0 21.3 17.9 14.7 10.3 12.4 10.7 20.4 10.6 14.5 14.3 13.7 23.9 13.4 12.7 16.7 17.1 14.6 17.0 12.2 15.0 20.0 13.7 34.0 36.2 16.4 20.1 15.7 12.2 9.3 15.5 20.5 53.4 14.7 14.3 15.1 13.7 18.9 13.4 28.3 11.3 24.3 20.4 13.4 17.1 20.7 15.6 6.3 5.9 3.1 5.7 4.8 6.9 1.1 26.7 18.3 24.9 14.3 11.7 16.5 12.4 17.5 17.6 20.0 23.9 18.6 21.5 26.0 28.4 15.3 17.3 23.4 14.8 31.5 24.9 15.5 18.8 15.7 10.5 19.9 26.1 16.5 18.6 12.6 21.4 26.3 17.1 17.7 15.0 18.4 13.0 21.6 5.7 33.0 17.6 22.5 20.9 37.4 14.3 19.0 23.3 24.8 18.2 19.4 25.4 19.9 13.3 19.3 21.0 13.2 19.6 34.9 28.1 18.1 37.5 17.0 13.7 22.2 1.9 2.7 3.1 6.9 2.8 4.4 4.7 6.1 4.7 2.3 6.3 5.8 6.0 1.1 4.8 5.7 5.9 5.4 1.1 11.5 27.5 19.0 21.3 13.4 12.7 12.2 15.0 20.1 11.3 DHX37 "DDX37, Dhr1, KIAA1517, MGC2695, MGC4322" ENSG00000150990 "DEAH-box helicase 37" Q8IY37 12 124946825-124989122 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047607 Approved Approved "Nuclear membrane" "Nuclear membrane" "HPA047607: " "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.32e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "prognostic unfavourable (9.54e-10)" "unprognostic (2.38e-2)" "unprognostic (5.14e-2)" "unprognostic (2.90e-2)" "unprognostic (2.07e-1)" "unprognostic (3.16e-2)" "unprognostic (8.28e-3)" "unprognostic (1.40e-2)" "unprognostic (2.27e-1)" "unprognostic (2.85e-2)" "unprognostic (2.73e-1)" 9.5 9.2 8.6 12.7 12.1 29.6 9.3 5.7 12.1 8.9 7.9 11.8 6.0 10.2 11.6 6.5 11.2 9.8 10.7 12.4 7.3 5.4 7.4 10.7 8.2 13.3 11.6 7.4 12.7 14.4 4.7 5.7 6.7 10.5 8.7 5.7 5.6 9.1 7.3 22.7 15.8 9.5 7.7 7.5 12.2 9.1 6.8 11.1 7.8 8.9 9.7 11.5 9.7 13.6 4.3 1.6 0.2 2.5 1.4 2.5 1.4 7.4 21.3 3.7 11.6 3.8 4.3 9.6 2.6 3.8 8.5 6.9 26.7 5.1 18.1 9.9 3.1 10.3 9.8 5.7 3.1 15.7 18.2 8.9 12.0 10.6 5.3 11.7 16.1 3.9 6.5 14.7 2.4 4.9 18.7 5.1 5.0 10.9 16.5 12.3 13.7 12.9 12.2 3.7 8.9 3.7 16.8 6.6 3.3 7.0 7.5 5.6 8.4 10.4 5.8 9.9 7.4 14.1 17.1 11.6 14.5 17.9 6.5 6.9 12.4 0.0 0.6 0.0 1.5 2.0 2.2 4.3 1.8 2.5 1.6 0.2 0.9 0.8 0.2 1.4 2.5 1.2 0.9 1.4 8.6 12.1 5.7 12.1 7.3 5.4 11.6 7.4 10.5 11.1 DHX38 "DDX38, hPrp16, KIAA0224, PRP16, PRPF16" ENSG00000140829 "DEAH-box helicase 38" Q92620 16 72093562-72112912 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041347, HPA041604" Uncertain Supported Nucleoplasm Nucleoplasm "HPA041347: AB_10796571, HPA041604: " "unprognostic (2.38e-1)" "unprognostic (1.89e-1)" "unprognostic (1.24e-2)" "unprognostic (3.25e-2)" "unprognostic (1.07e-1)" "unprognostic (1.01e-1)" "unprognostic (6.32e-3)" "unprognostic (8.50e-3)" "unprognostic (6.97e-2)" "unprognostic (1.45e-1)" "unprognostic (7.92e-2)" "unprognostic (1.28e-3)" "unprognostic (4.20e-3)" "unprognostic (2.68e-1)" "unprognostic (9.46e-2)" "unprognostic (2.40e-1)" "unprognostic (2.40e-2)" 21.8 16.5 21.1 22.2 25.0 35.1 20.5 36.0 29.4 18.6 19.5 23.5 19.4 20.1 24.1 13.5 21.1 19.9 18.1 19.2 24.1 13.7 17.3 20.8 20.6 26.1 24.1 20.7 29.0 17.3 36.6 18.7 19.3 20.9 18.3 17.2 17.9 20.4 16.4 33.0 27.2 23.0 23.5 22.5 27.3 19.4 17.5 27.8 24.6 20.8 23.2 23.1 20.5 21.4 10.4 8.1 8.3 10.6 11.8 14.9 6.3 14.4 21.5 15.7 8.7 13.7 10.6 20.6 13.1 12.8 19.6 15.1 26.1 14.5 19.3 11.8 19.7 19.1 18.1 18.0 15.2 9.6 19.5 14.8 18.3 35.5 12.7 17.4 26.9 14.7 16.6 26.4 19.1 16.9 21.9 9.2 12.0 44.6 16.6 19.7 19.7 12.4 21.5 10.8 19.1 9.4 13.8 14.1 15.5 16.8 8.0 9.3 14.6 14.5 19.1 18.9 16.8 13.7 14.3 22.7 17.9 37.1 17.8 12.1 14.7 7.4 7.9 8.3 14.9 10.6 13.7 10.4 9.3 10.7 8.1 8.2 10.4 10.8 8.2 11.8 6.6 7.4 10.9 6.3 21.1 25.0 36.0 29.4 24.1 13.7 24.1 20.7 20.9 27.8 DHX40 "ARG147, DDX40, FLJ22060, PAD" ENSG00000108406 "DEAH-box helicase 40" Q8IX18 17 59565525-59608345 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044350 Uncertain Supported Nucleoplasm Nucleoplasm "HPA044350: AB_10960560" "unprognostic (1.58e-2)" "unprognostic (3.10e-1)" "prognostic favourable (4.05e-5)" "unprognostic (4.09e-2)" "unprognostic (5.23e-2)" "unprognostic (2.84e-1)" "unprognostic (4.57e-3)" "unprognostic (7.53e-3)" "unprognostic (2.86e-2)" "unprognostic (1.80e-1)" "unprognostic (7.23e-2)" "unprognostic (3.08e-1)" "unprognostic (9.48e-3)" "unprognostic (2.22e-1)" "unprognostic (1.25e-2)" "unprognostic (1.11e-1)" "unprognostic (3.10e-1)" 22.4 24.2 16.2 14.0 18.1 19.5 24.8 21.7 18.4 21.4 16.5 17.5 23.7 12.8 27.0 25.0 19.3 24.8 16.5 19.8 17.1 19.5 29.5 13.1 16.7 16.8 17.9 14.7 29.7 21.0 51.3 45.8 21.9 19.0 21.6 15.4 13.7 19.3 27.8 20.4 21.3 12.3 18.9 19.9 15.6 17.2 28.4 16.8 26.1 28.2 16.0 15.5 26.0 19.7 5.4 6.9 18.8 6.6 4.2 10.6 6.1 11.5 21.3 27.1 17.6 16.6 17.2 14.9 10.5 20.1 16.1 18.2 8.3 11.6 15.2 29.5 15.0 8.6 19.3 14.8 25.0 12.0 28.2 13.9 16.0 9.2 13.0 16.7 6.5 13.1 13.7 13.6 13.2 17.1 11.6 14.1 10.9 21.0 20.5 10.3 10.3 15.6 19.7 19.0 16.6 16.1 9.3 19.3 47.5 18.9 7.5 19.2 24.4 9.8 13.9 19.4 24.2 6.9 10.2 17.4 19.1 9.8 22.8 11.7 13.2 8.5 6.6 10.5 8.1 6.5 10.6 5.1 5.9 5.8 6.9 5.4 5.9 6.9 18.8 4.2 4.4 3.5 6.0 6.1 16.2 18.1 21.7 18.4 17.1 19.5 17.9 14.7 19.0 16.8 DHX57 DDX57 ENSG00000163214 "DExH-box helicase 57" Q6P158 2 38797729-38875934 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036160 Uncertain Approved "Nucleoli,Intermediate filaments,Microtubules,Cytosol" "Intermediate filaments, Microtubules" "Nucleoli, Cytosol" "HPA036160: AB_10670711" "unprognostic (6.78e-2)" "unprognostic (3.08e-1)" "unprognostic (3.49e-2)" "unprognostic (2.03e-3)" "unprognostic (3.25e-2)" "unprognostic (3.43e-1)" "prognostic unfavourable (3.32e-6)" "unprognostic (1.75e-2)" "unprognostic (2.74e-1)" "unprognostic (1.45e-1)" "unprognostic (7.35e-2)" "unprognostic (1.82e-2)" "unprognostic (2.55e-2)" "unprognostic (1.47e-1)" "unprognostic (3.88e-2)" "unprognostic (7.03e-3)" "unprognostic (1.77e-1)" 9.6 11.2 9.7 8.5 16.7 7.0 10.4 11.9 16.4 14.1 9.4 9.9 9.8 4.2 13.9 17.1 8.4 11.2 9.5 9.3 9.6 11.0 11.2 7.2 7.9 9.2 8.9 9.5 13.2 9.5 18.9 17.9 11.2 13.1 10.5 9.2 11.6 7.8 14.2 11.5 11.1 6.9 11.8 7.7 9.9 7.9 27.7 8.3 13.9 11.8 8.1 11.1 10.5 8.3 7.1 5.2 1.7 10.1 3.3 6.0 4.2 16.9 13.6 15.2 11.4 10.0 12.4 12.5 11.8 11.6 11.2 11.0 10.9 5.2 4.9 11.9 12.0 8.8 17.2 13.0 18.4 20.4 12.7 9.6 9.1 14.8 9.1 10.1 5.6 11.8 7.9 14.5 9.1 14.9 12.3 7.0 12.1 12.3 10.1 9.3 19.0 8.1 5.0 20.2 9.7 10.3 6.5 12.6 18.5 11.8 12.2 13.8 8.5 5.6 11.4 11.1 12.9 8.5 12.6 7.4 8.2 2.1 8.7 7.1 7.4 1.7 10.1 1.7 4.5 6.9 6.0 5.7 4.0 3.5 5.2 7.1 4.8 3.0 0.5 3.3 8.0 1.7 3.3 4.2 9.7 16.7 11.9 16.4 9.6 11.0 8.9 9.5 13.1 8.3 DHX58 "D11LGP2, LGP2" ENSG00000108771 "DExH-box helicase 58" Q96C10 17 42101404-42112733 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 24.4;BJ hTERT+ SV40 Large T+ RasG12V: 28.5;SK-MEL-30: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018670, HPA019570" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" Nucleoplasm "HPA018670: AB_1847665, HPA019570: AB_1847666" "prognostic favourable (3.45e-4)" "unprognostic (1.03e-2)" "unprognostic (3.56e-3)" "unprognostic (1.54e-2)" "unprognostic (2.45e-2)" "unprognostic (4.82e-2)" "unprognostic (2.05e-3)" "unprognostic (5.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.15e-1)" "unprognostic (6.02e-2)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (8.65e-2)" "unprognostic (8.01e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" 12.7 16.3 6.7 15.3 7.8 11.1 9.8 2.8 8.4 7.9 9.8 9.6 15.0 8.2 9.6 16.2 8.7 12.0 12.6 5.3 6.5 5.3 11.0 20.9 21.7 14.4 5.9 9.0 12.9 7.4 4.3 9.6 7.0 8.2 10.6 5.0 13.4 18.0 17.1 6.9 7.8 10.5 9.2 7.9 17.1 9.1 10.7 5.1 17.2 7.5 5.6 12.9 10.9 7.6 6.4 7.6 8.6 12.0 7.6 7.1 5.9 1.2 0.0 0.0 0.7 6.2 5.3 0.2 1.7 11.8 24.4 28.5 0.1 7.6 0.1 1.8 2.8 1.0 0.1 1.9 0.9 4.7 0.1 2.0 1.1 0.4 6.9 1.8 4.6 8.6 3.2 2.1 2.1 2.9 0.0 6.7 1.3 0.0 10.9 2.2 0.2 0.0 3.9 0.0 0.5 2.7 4.4 0.2 0.0 0.7 3.1 13.9 4.2 1.9 1.2 1.2 0.0 0.4 0.6 2.3 1.9 0.1 2.4 1.7 1.3 3.1 9.9 8.6 4.5 12.0 6.5 6.4 6.4 4.0 7.6 4.9 7.1 5.3 4.0 7.6 10.5 2.5 5.5 5.9 6.7 7.8 2.8 8.4 6.5 5.3 5.9 9.0 8.2 5.1 DHX8 "DDX8, Dhr2, HRH1, PRP22, PRPF22" ENSG00000067596 "DEAH-box helicase 8" Q14562 17 43483865-43544463 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049285 Approved Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Nucleoplasm "Nuclear bodies" "HPA049285: " "unprognostic (2.99e-1)" "unprognostic (4.42e-2)" "unprognostic (5.64e-2)" "unprognostic (9.02e-2)" "unprognostic (1.25e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-3)" "unprognostic (9.43e-2)" "unprognostic (2.58e-1)" "unprognostic (3.40e-2)" "unprognostic (2.26e-2)" "unprognostic (2.47e-1)" "unprognostic (1.50e-1)" "unprognostic (4.04e-1)" "unprognostic (5.08e-3)" "unprognostic (2.60e-1)" "unprognostic (6.28e-2)" 21.9 18.6 17.5 17.0 22.9 47.8 22.3 21.6 29.8 20.3 21.0 25.3 17.2 17.1 26.1 28.4 26.6 17.9 16.7 18.5 18.1 18.7 18.5 20.1 19.8 21.0 20.8 19.7 19.5 17.4 35.4 23.0 21.7 22.7 22.1 24.6 20.1 21.7 21.7 25.2 32.9 22.0 24.6 19.2 27.3 19.5 34.6 20.6 40.8 20.5 17.8 28.9 19.4 22.6 11.5 16.3 23.3 20.4 9.5 14.9 9.8 12.3 35.1 19.1 23.7 19.0 19.5 10.6 13.0 27.5 28.8 27.7 16.0 12.6 17.1 12.1 25.5 16.8 28.6 22.9 33.8 17.9 22.6 14.5 26.8 24.7 16.3 25.1 22.0 9.7 19.4 23.6 26.0 25.4 16.1 16.9 22.2 13.4 31.8 22.4 15.5 13.4 19.4 36.4 17.6 19.5 25.9 16.5 24.9 14.6 8.4 11.7 19.5 24.8 17.3 22.4 12.2 16.1 19.4 12.7 15.1 19.4 18.6 15.7 17.9 23.3 15.2 17.2 13.7 20.4 13.6 11.5 11.4 14.9 16.3 10.6 11.2 10.9 19.2 9.5 19.6 8.4 11.7 9.8 17.5 22.9 21.6 29.8 18.1 18.7 20.8 19.7 22.7 20.6 DHX9 "DDX9, LKP, RHA" ENSG00000135829 "DExH-box helicase 9" Q08211 1 182839369-182887751 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, DNA replication, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, mRNA processing, mRNA splicing, mRNA transport, RNA-mediated gene silencing, Transcription, Transcription regulation, Transcription termination, Translation regulation, Transport" "Activator, DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011819, HPA028050" Supported Supported Nucleoplasm 97000 Nucleoplasm "CAB011819: AB_777725, HPA028050: AB_10603564" "unprognostic (8.14e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-2)" "unprognostic (4.80e-2)" "unprognostic (1.58e-1)" "unprognostic (7.40e-2)" "prognostic unfavourable (3.17e-4)" "unprognostic (9.98e-2)" "prognostic unfavourable (6.04e-4)" "unprognostic (2.76e-1)" "unprognostic (2.88e-2)" "unprognostic (5.53e-2)" "unprognostic (7.51e-2)" "unprognostic (1.43e-1)" "unprognostic (1.70e-1)" "unprognostic (3.17e-1)" "unprognostic (1.99e-1)" 30.2 25.9 25.7 28.5 28.6 68.9 32.9 42.5 33.1 31.9 24.5 23.3 25.2 19.8 38.2 24.2 27.7 30.6 19.7 22.9 24.4 22.6 36.2 31.4 27.8 32.0 34.2 23.1 37.5 24.9 51.8 35.8 28.5 28.0 25.7 30.1 21.1 28.2 29.4 27.6 26.6 27.0 31.6 25.3 32.8 26.5 29.4 37.4 68.3 30.1 31.6 41.2 32.4 31.9 16.8 22.9 12.0 17.4 14.7 21.9 15.0 35.1 34.5 49.5 27.2 25.9 20.1 48.9 31.2 28.6 45.4 30.8 38.5 27.2 56.5 30.5 28.0 30.5 75.1 33.8 50.8 22.9 37.3 37.6 28.2 26.0 14.6 54.4 25.8 17.9 17.0 44.5 12.1 35.4 59.0 20.3 36.3 30.9 55.0 13.4 62.7 21.3 50.2 46.2 32.3 29.3 40.9 35.7 41.0 44.2 28.0 18.2 32.7 30.8 27.6 28.2 31.5 28.6 42.2 21.3 34.8 67.1 17.7 29.9 38.2 5.6 16.0 12.0 19.2 17.4 21.9 16.8 16.8 17.6 22.9 14.6 18.4 19.9 6.5 14.7 14.3 11.1 15.4 15.0 25.7 28.6 42.5 33.1 24.4 22.6 34.2 23.1 28.0 37.4 DICER1 "Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1" ENSG00000100697 "Dicer 1, ribonuclease III" Q9UPY3 14 95086228-95158010 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing" "Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000694, CAB068185" Approved Supported Cytosol Cytosol "CAB068185: , HPA000694: AB_1078661" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" "unprognostic (6.75e-2)" "unprognostic (9.62e-2)" "unprognostic (1.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.21e-1)" "unprognostic (8.52e-3)" "unprognostic (5.73e-2)" "unprognostic (9.22e-2)" "unprognostic (4.22e-2)" "unprognostic (9.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.04e-3)" "unprognostic (3.74e-2)" 23.2 12.5 18.4 22.4 33.3 20.5 23.2 28.5 29.9 19.0 18.1 31.4 22.4 13.0 20.8 20.6 23.4 18.5 16.2 15.3 22.0 14.1 19.5 23.6 22.4 20.3 29.7 19.6 23.8 19.8 26.9 30.9 29.9 23.2 20.3 19.7 14.5 19.5 18.9 28.0 20.7 17.3 19.0 26.8 20.7 17.1 20.6 32.0 17.0 23.8 14.7 20.3 20.7 24.1 2.5 1.8 10.7 7.2 1.2 3.3 1.0 12.8 13.4 25.1 9.3 6.5 9.8 19.9 10.6 6.4 6.8 8.2 17.0 9.9 14.5 11.5 9.8 15.2 19.9 10.0 14.2 22.5 8.9 21.9 7.4 12.2 6.6 13.4 13.5 9.1 8.3 9.1 13.9 10.1 9.2 12.9 11.4 18.0 15.0 8.9 7.1 6.6 12.0 20.5 8.0 9.0 20.5 20.8 11.8 10.7 11.0 12.0 12.4 9.9 10.0 5.2 10.3 10.1 11.9 14.8 21.1 20.6 5.4 10.9 9.3 3.1 3.0 1.2 1.6 3.1 3.3 1.9 1.5 1.2 1.8 2.5 1.5 1.3 10.7 1.2 7.2 1.6 1.6 1.0 18.4 33.3 28.5 29.9 22.0 14.1 29.7 19.6 23.2 32.0 DIMT1 "DIMT1L, HSA9761" ENSG00000086189 "DIM1 dimethyladenosine transferase 1 homolog" Q9UNQ2 5 62387254-62403939 "Enzymes, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042944 Approved Supported Nucleoplasm,Nucleoli,Cytosol Nucleoli "Nucleoplasm, Cytosol" "HPA042944: " "unprognostic (1.58e-1)" "unprognostic (2.27e-1)" "unprognostic (6.02e-3)" "unprognostic (7.16e-2)" "unprognostic (8.95e-3)" "unprognostic (1.73e-2)" "prognostic unfavourable (6.93e-4)" "unprognostic (8.88e-2)" "unprognostic (1.18e-2)" "unprognostic (1.62e-1)" "unprognostic (5.31e-2)" "unprognostic (3.70e-1)" "prognostic unfavourable (8.90e-12)" "unprognostic (8.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.49e-1)" "unprognostic (5.15e-2)" 16.7 14.0 18.9 16.7 17.0 10.6 18.9 11.5 23.5 18.6 11.8 12.4 11.8 11.0 16.2 11.9 20.1 14.2 15.3 19.7 19.1 17.0 11.9 16.3 11.7 22.5 18.8 8.5 17.8 28.4 8.9 13.4 16.7 12.3 18.8 9.5 10.0 16.1 18.3 17.9 12.2 11.9 24.6 20.2 22.1 10.2 10.7 9.8 16.3 19.0 19.0 19.2 21.7 13.2 7.9 7.7 5.0 5.6 7.0 13.2 6.1 14.4 8.7 15.9 20.8 11.8 15.7 15.9 18.6 7.0 14.4 15.3 14.1 15.5 29.8 17.0 13.8 11.3 10.7 11.0 18.3 21.2 18.7 20.5 11.4 11.7 14.2 16.8 15.8 13.6 8.9 14.0 13.7 12.5 20.7 13.8 14.6 14.5 24.7 25.9 15.4 18.4 16.0 16.1 41.1 13.0 13.4 17.9 15.6 15.9 14.9 15.9 12.0 15.8 13.8 9.9 10.4 14.0 25.4 18.2 18.9 26.9 15.1 30.2 14.6 5.0 3.1 2.3 7.7 5.6 11.7 7.9 10.4 9.3 5.0 6.6 13.2 11.0 0.8 7.0 4.3 7.7 9.3 6.1 18.9 17.0 11.5 14.7 19.1 17.0 18.8 8.5 12.3 9.8 DIO2 "SelY, TXDI2" ENSG00000211448 "Iodothyronine deiodinase 2" Q92813 14 80197527-80387757 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 67.7;thyroid gland: 128.7" "Cell line enhanced" "Detected in some" "BJ: 26.1;fHDF/TERT166: 14.3;HeLa: 29.9;HHSteC: 14.9;SiHa: 54.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029544, HPA048002" Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA029544: AB_10600804, HPA048002: " "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "prognostic favourable (1.67e-4)" "prognostic favourable (4.62e-6)" "unprognostic (2.76e-1)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.17e-1)" "unprognostic (2.07e-1)" "unprognostic (8.78e-2)" "unprognostic (3.68e-2)" "unprognostic (2.48e-1)" "unprognostic (1.00e-3)" "unprognostic (5.08e-2)" "unprognostic (3.43e-1)" "unprognostic (8.40e-2)" "unprognostic (7.15e-2)" 1.3 1.8 13.0 0.9 12.3 0.7 6.1 1.0 19.7 67.7 1.2 1.6 1.9 1.2 15.6 1.1 36.1 0.9 2.5 4.7 14.2 2.7 2.4 0.7 1.2 1.0 4.1 7.6 0.7 1.3 0.9 35.9 5.9 13.2 5.0 1.3 13.1 17.7 12.4 3.0 3.3 1.2 2.4 1.2 0.9 2.5 2.5 1.4 0.0 128.7 15.8 12.0 2.6 13.7 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.4 0.0 26.1 5.5 2.3 0.3 0.0 0.1 0.0 0.1 14.3 0.5 0.9 0.0 1.9 0.0 0.0 0.0 29.9 0.0 14.9 0.0 0.0 1.6 0.0 0.5 0.0 0.5 0.0 0.2 0.1 0.6 0.0 0.0 0.5 0.1 0.2 1.2 0.0 0.0 0.2 0.0 0.0 54.7 11.4 0.1 0.0 0.0 0.3 0.1 2.4 5.5 6.6 0.8 0.0 0.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 13.0 12.3 1.0 19.7 14.2 2.7 4.1 7.6 13.2 1.4 DLAT "DLTA, PDC-E2" ENSG00000150768 "Dihydrolipoamide S-acetyltransferase" P10515 11 112024814-112064390 "Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 55.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003782, HPA040786, HPA062766" Supported Enhanced Mitochondria Mitochondria "CAB003782: , HPA040786: AB_2677136, HPA062766: AB_2684864" "unprognostic (4.57e-3)" "unprognostic (1.75e-1)" "prognostic favourable (6.19e-6)" "unprognostic (7.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-2)" "prognostic unfavourable (7.49e-5)" "unprognostic (8.68e-2)" "unprognostic (5.36e-2)" "unprognostic (2.93e-1)" "unprognostic (2.23e-3)" "unprognostic (6.25e-2)" "prognostic favourable (1.95e-14)" "unprognostic (5.82e-2)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (6.15e-2)" 14.1 10.7 10.6 8.8 11.9 4.8 10.9 10.5 14.2 6.7 13.3 6.3 7.8 12.4 6.3 8.1 12.2 7.2 6.4 55.4 10.4 13.5 19.1 12.0 6.6 8.7 11.2 9.7 7.9 6.0 15.8 7.8 8.3 13.0 8.3 13.5 7.6 10.4 9.9 41.0 7.2 13.0 6.6 7.3 6.9 8.1 7.3 4.2 12.7 10.7 22.1 8.8 7.5 6.7 9.2 9.1 7.9 8.9 7.2 10.3 8.0 6.0 6.1 8.1 10.8 11.4 8.5 9.7 8.3 4.8 9.2 10.4 19.3 17.8 24.8 16.3 7.6 13.0 16.9 8.9 10.5 8.9 10.5 15.7 6.5 11.9 8.2 19.9 9.0 10.3 9.8 9.2 9.3 8.4 25.7 11.9 10.8 4.7 9.0 23.9 9.5 11.8 14.0 11.0 27.9 16.9 6.4 15.6 9.5 10.0 28.3 6.3 21.0 12.4 5.6 9.2 10.0 9.2 10.6 3.9 6.2 37.6 2.6 21.8 7.2 7.9 6.6 4.7 8.3 8.9 9.5 9.2 8.2 8.9 9.1 7.5 10.3 8.3 0.5 7.2 8.9 7.4 8.8 8.0 10.6 11.9 10.5 14.2 10.4 13.5 11.2 9.7 13.0 4.2 DLD "DLDH, GCSL, LAD" ENSG00000091140 "Dihydrolipoamide dehydrogenase" P09622 7 107890970-107931730 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044849 Supported Supported Mitochondria 16000000 Mitochondria "HPA044849: " "unprognostic (2.01e-3)" "unprognostic (2.26e-1)" "unprognostic (1.27e-2)" "unprognostic (9.27e-2)" "unprognostic (5.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.48e-1)" "unprognostic (2.83e-2)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (9.43e-2)" "unprognostic (7.35e-2)" "prognostic favourable (7.58e-9)" "unprognostic (4.08e-2)" "unprognostic (1.88e-1)" "unprognostic (4.45e-3)" "unprognostic (1.18e-1)" 25.7 37.9 14.5 12.7 25.4 12.0 15.2 16.6 27.2 13.2 28.0 10.6 12.2 20.9 13.6 9.6 25.6 11.6 12.7 69.1 16.4 14.4 40.7 37.9 11.0 13.0 16.7 20.1 15.1 14.8 24.6 22.4 15.4 29.3 14.7 26.8 12.8 19.4 14.4 71.5 13.8 29.5 23.7 10.6 17.4 23.0 10.6 10.7 18.7 17.0 31.8 16.9 20.1 11.7 13.5 30.4 45.8 37.8 22.9 19.4 20.2 39.9 32.4 18.0 31.0 25.9 22.9 20.4 23.0 19.4 26.8 20.8 37.9 22.4 39.1 39.7 24.4 26.6 36.2 32.4 40.5 26.1 21.5 27.5 43.0 27.0 19.9 45.2 28.4 26.1 23.6 28.4 15.5 32.1 68.6 29.2 29.0 44.9 36.9 32.8 21.4 23.5 26.6 28.8 53.0 36.6 59.8 22.4 23.7 37.7 63.7 33.8 24.2 38.7 20.3 29.6 24.3 57.6 34.9 22.1 42.1 26.3 27.9 48.3 30.6 36.5 22.3 45.8 17.5 28.2 18.5 13.5 17.7 17.3 30.4 12.3 18.7 19.4 14.0 22.9 37.8 10.5 16.8 20.2 14.5 25.4 16.6 27.2 16.4 14.4 16.7 20.1 29.3 10.7 DLST DLTS ENSG00000119689 "Dihydrolipoamide S-succinyltransferase" P36957 14 74881891-74903745 "Citric acid cycle related proteins, Enzymes, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003010 Supported 800000 "HPA003010: AB_1078679" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "unprognostic (2.45e-3)" "unprognostic (6.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (1.16e-1)" "unprognostic (5.83e-2)" "unprognostic (3.03e-1)" "unprognostic (1.37e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-1)" "prognostic favourable (1.13e-12)" "unprognostic (3.29e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "unprognostic (4.55e-3)" 32.2 38.6 12.0 22.7 19.9 28.5 31.3 19.1 25.6 31.2 36.0 18.5 15.9 24.7 26.3 28.3 31.4 19.2 29.7 47.6 10.8 11.8 43.7 45.1 20.8 26.7 13.5 13.7 21.5 27.1 25.8 16.2 25.2 19.7 20.9 26.8 19.2 22.3 20.1 59.2 26.9 43.2 32.9 11.4 20.8 24.3 21.0 10.4 23.5 27.2 49.8 28.4 26.9 21.1 3.8 6.3 8.4 4.3 7.7 5.3 3.2 26.3 27.5 21.0 14.9 33.0 37.5 32.3 34.4 35.0 35.2 33.0 27.0 28.6 26.8 14.7 39.5 29.7 35.4 34.0 37.3 19.4 14.8 21.8 23.0 23.6 34.2 15.5 15.1 38.4 29.8 34.1 42.1 36.3 16.7 18.2 38.2 35.3 18.4 22.0 18.0 25.9 23.5 30.9 14.7 43.7 32.4 25.1 21.2 32.5 43.4 22.4 39.7 22.4 32.1 21.4 28.1 26.2 23.5 12.9 13.4 23.5 31.4 16.1 22.4 8.4 3.0 5.0 5.0 4.3 4.5 3.8 4.5 3.9 4.7 2.7 4.0 5.3 3.0 7.7 3.9 6.3 4.4 3.2 12.0 19.9 19.1 25.6 10.8 11.8 13.5 13.7 19.7 10.4 DMGDH ENSG00000132837 "Dimethylglycine dehydrogenase" Q9UI17 5 78997606-79236038 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "kidney: 50.2;liver: 81.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 5.6;Hep G2: 11.3;hTEC/SVTERT24-B: 3.5;Karpas-707: 3.6" "Group enriched" "Detected in some" 12 "liver cancer: 15.6;renal cancer: 12.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036441, HPA036442, HPA077849" Enhanced Supported Mitochondria 440000 Mitochondria "HPA036441: AB_2675124, HPA036442: AB_10669792, HPA077849: " "unprognostic (3.11e-2)" "unprognostic (3.36e-1)" "unprognostic (6.70e-2)" "unprognostic (1.81e-1)" "unprognostic (3.15e-1)" "unprognostic (2.52e-3)" "prognostic favourable (5.32e-5)" "unprognostic (2.21e-1)" "unprognostic (3.05e-2)" "unprognostic (3.19e-2)" "unprognostic (1.07e-4)" "unprognostic (1.89e-1)" "prognostic favourable (1.17e-5)" "unprognostic (2.03e-2)" "unprognostic (9.75e-4)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" 2.8 2.2 0.8 0.8 1.3 0.0 1.5 0.4 0.6 0.5 0.5 0.7 1.9 0.1 0.9 5.9 0.4 0.4 0.6 1.3 0.8 0.8 50.2 81.8 0.1 0.1 0.8 0.3 1.0 0.5 0.3 2.1 0.0 1.1 0.9 0.1 2.7 0.4 1.1 0.6 0.2 0.3 2.0 1.7 0.0 0.4 1.2 0.2 0.0 1.5 0.8 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.5 0.5 1.4 0.4 0.3 5.6 1.3 2.3 0.0 0.1 0.0 0.4 1.7 0.0 0.1 0.0 1.8 0.3 0.0 0.0 0.0 11.3 3.1 0.0 0.0 2.7 3.3 3.5 2.5 0.0 0.0 3.6 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 3.2 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.8 1.3 0.4 0.6 0.8 0.8 0.8 0.3 1.1 0.2 DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769717-45782552 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 79.6" "Cell line enhanced" "Detected in many" "RH-30: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007164, HPA008905" Enhanced Approved Vesicles,Cytosol Cytosol Vesicles "HPA007164: AB_1078687, HPA008905: AB_1078685" "unprognostic (7.44e-2)" "unprognostic (2.66e-1)" "unprognostic (1.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "prognostic favourable (9.39e-5)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (4.24e-3)" 9.0 18.7 5.1 9.7 6.3 1.7 4.9 8.8 6.2 16.5 23.4 4.4 15.6 8.7 21.2 15.0 31.2 13.7 20.3 56.7 5.0 5.3 4.9 2.2 6.5 4.1 4.8 6.5 8.4 33.3 3.1 10.7 6.8 5.6 16.3 3.8 22.0 6.1 19.7 79.6 5.1 11.3 65.1 4.2 5.3 12.0 5.9 4.0 1.1 6.1 36.6 5.0 44.9 8.2 1.5 0.0 0.0 0.8 0.3 2.2 0.0 7.2 10.1 12.0 7.4 8.1 11.3 7.2 16.2 12.0 6.5 6.3 1.2 3.9 2.3 2.4 18.5 10.6 3.4 1.6 2.4 11.3 10.6 0.9 12.6 1.7 7.9 0.1 4.1 16.5 5.7 5.6 2.7 3.0 7.1 5.8 9.4 8.0 1.1 2.7 7.1 2.2 3.7 44.2 3.7 3.5 8.3 6.5 10.3 8.8 18.5 5.2 15.2 3.5 9.1 7.6 7.5 7.2 11.8 11.2 9.6 2.3 6.9 1.0 10.6 0.0 0.0 0.0 2.2 0.8 0.5 0.3 0.7 0.2 0.0 1.5 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 5.1 6.3 8.8 6.2 5.0 5.3 4.8 6.5 5.6 4.0 DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease mutation, Dwarfism, Mental retardation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 49.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "NK-cell: 5.5" "Lineage enriched" "Detected in single" 6 "NK-cells: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037487, HPA057526" Approved Supported Mitochondria Mitochondria "HPA037487: AB_10672493, HPA057526: " "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" 1.6 1.2 2.0 13.7 2.4 7.0 3.0 6.2 3.8 1.6 4.5 1.1 0.8 3.5 3.0 1.8 3.2 1.0 2.4 2.0 2.5 2.2 3.4 6.2 3.3 8.4 2.9 5.0 1.9 2.4 1.1 2.3 4.0 1.7 3.0 5.0 0.9 2.3 0.8 2.3 2.9 5.2 1.9 3.0 5.2 2.6 7.0 1.4 49.1 1.5 5.1 10.8 2.3 2.0 0.4 0.1 0.9 0.1 5.5 0.6 0.1 13.7 7.1 16.3 11.5 1.8 1.3 11.5 6.8 5.7 9.8 12.1 17.0 9.0 14.1 2.6 2.1 8.5 9.3 3.6 11.8 8.7 7.0 8.6 4.4 6.5 0.5 14.7 9.3 1.0 1.4 7.0 2.0 4.4 12.5 12.8 5.6 4.8 22.7 10.7 11.5 13.4 17.8 11.3 4.5 4.2 6.4 7.4 8.9 9.4 11.9 2.2 9.2 6.3 1.8 3.8 11.7 4.8 12.9 6.5 7.3 21.1 3.2 14.1 4.9 0.0 0.0 0.9 0.2 0.0 0.2 0.4 0.2 0.6 0.1 0.4 0.3 0.3 0.1 5.5 0.1 0.0 0.4 0.1 2.0 2.4 6.2 3.8 2.5 2.2 2.9 5.0 1.7 1.4 DNAJC6 "KIAA0473, PARK19" ENSG00000116675 "DnaJ heat shock protein family (Hsp40) member C6" O75061 1 65248219-65415869 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chaperone, Hydrolase, Protein phosphatase" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 91.4" "Cell line enhanced" "Detected in many" "HDLM-2: 20.9;HEL: 55.8;K-562: 21.7" "Cancer enhanced" "Detected in many" "glioma: 5.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "gdT-cell: 1.5" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031182, HPA054917" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" Cytosol "Nucleoplasm, Plasma membrane" "HPA031182: AB_10611957, HPA054917: " "unprognostic (6.99e-2)" "unprognostic (2.00e-3)" "unprognostic (3.19e-1)" "unprognostic (7.94e-7)" "unprognostic (1.59e-1)" "unprognostic (7.61e-3)" "unprognostic (1.87e-4)" "unprognostic (2.98e-1)" "unprognostic (1.89e-1)" "unprognostic (4.14e-1)" "unprognostic (4.22e-3)" "unprognostic (1.53e-1)" "prognostic favourable (2.81e-4)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-1)" "unprognostic (8.67e-3)" 2.1 12.1 18.6 2.2 28.5 5.0 2.0 24.2 91.4 2.2 2.8 26.9 0.0 2.3 1.9 1.8 1.7 2.4 2.3 9.0 25.0 26.7 8.5 1.6 2.7 1.6 28.8 23.8 1.9 3.4 2.1 7.5 8.0 40.5 2.5 3.0 2.2 1.7 2.1 1.6 2.1 2.3 2.2 28.7 3.2 2.9 3.2 21.1 0.0 3.0 0.0 1.7 1.8 0.6 0.5 0.5 0.0 0.0 0.6 1.5 0.3 3.5 0.9 0.0 1.6 0.7 0.2 8.3 7.0 11.4 11.5 11.3 0.9 0.1 3.3 0.6 2.9 0.8 5.0 1.1 9.1 20.9 2.4 55.8 1.9 0.2 0.0 1.8 1.4 1.0 0.8 1.1 4.9 0.2 21.7 0.4 2.3 0.6 0.7 0.0 2.3 0.7 0.0 1.7 0.1 8.7 0.0 13.9 9.6 4.1 5.5 1.9 2.6 0.1 2.1 1.7 1.2 0.2 2.0 2.1 1.3 1.0 4.7 1.4 2.8 0.0 0.0 0.0 1.5 0.0 0.1 0.5 0.5 0.9 0.0 0.0 0.4 0.6 0.0 0.6 0.0 0.5 0.0 0.3 18.6 28.5 24.2 37.4 25.0 26.7 28.8 23.8 40.5 21.1 DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 26.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted in other tissues" 160000 Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favourable (1.14e-4)" 1.5 1.4 1.5 2.6 1.6 1.7 1.5 3.8 2.5 2.2 12.2 1.8 1.5 14.9 1.5 2.2 3.4 1.2 2.5 1.5 1.5 1.2 11.4 1.5 1.5 4.4 1.5 1.5 2.0 13.7 1.6 12.2 1.9 3.1 5.1 2.1 1.5 3.3 1.5 1.5 3.9 26.7 1.5 1.5 2.3 6.0 2.7 1.5 1.5 1.6 2.6 3.8 1.9 2.3 4.5 2.2 9.2 2.0 1.9 3.4 1.0 2.4 5.7 10.0 5.2 2.9 2.5 4.8 4.0 0.7 3.2 4.7 6.8 6.0 10.5 3.2 0.6 4.2 3.6 1.1 3.5 4.6 5.5 3.7 8.5 4.5 1.5 2.6 8.5 2.0 4.2 4.3 1.0 2.1 9.2 4.7 2.7 10.2 5.2 11.3 6.1 3.1 12.4 4.6 5.1 2.7 2.1 7.1 6.6 2.9 9.1 1.6 9.0 6.5 2.9 6.0 4.5 3.8 2.2 4.2 6.0 18.2 1.7 4.8 5.8 4.3 2.0 5.3 3.0 1.3 1.9 2.5 2.3 2.4 1.0 4.5 2.7 3.4 9.2 1.9 1.2 2.2 2.4 1.0 1.5 1.6 3.8 2.5 1.5 1.2 1.5 1.5 3.1 1.5 DNASE2 "DNL, DNL2" ENSG00000105612 "Deoxyribonuclease 2, lysosomal" O00115 19 12875211-12881468 "Enzymes, Predicted intracellular proteins" Apoptosis "Developmental protein, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066185 Enhanced "Intracellular and membrane" 720000 "HPA066185: " "unprognostic (9.62e-2)" "unprognostic (2.19e-3)" "unprognostic (8.97e-2)" "unprognostic (7.45e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (5.42e-2)" "unprognostic (4.85e-2)" "unprognostic (1.40e-1)" "unprognostic (5.12e-2)" "unprognostic (4.37e-2)" "unprognostic (2.58e-2)" "unprognostic (4.69e-2)" "unprognostic (3.57e-1)" "unprognostic (1.98e-1)" 18.7 22.1 13.1 17.0 13.4 4.8 16.9 6.0 12.9 21.2 22.8 15.9 15.8 14.6 19.6 27.9 22.7 17.0 20.6 18.0 11.5 9.4 17.1 40.7 37.4 34.5 14.9 7.7 20.0 33.3 21.2 18.9 28.1 11.6 18.4 13.5 22.6 24.9 18.0 16.6 20.5 15.9 14.6 13.1 24.1 20.9 9.4 11.0 20.0 36.4 13.6 26.9 20.5 14.8 11.8 10.3 20.1 37.8 21.9 26.6 19.6 16.3 8.3 0.7 22.4 24.7 12.9 14.7 8.4 23.3 8.6 21.9 0.7 11.7 7.8 24.4 15.1 19.2 8.7 8.8 4.8 21.6 9.7 3.5 9.9 4.2 19.9 7.0 32.5 12.6 20.9 6.8 10.6 12.9 3.1 32.4 5.7 21.3 6.8 3.8 1.4 14.9 4.4 3.9 17.2 9.4 6.9 4.8 7.3 12.7 18.4 31.2 27.2 6.5 7.7 17.9 5.7 17.8 7.7 35.5 36.3 9.7 29.8 6.5 9.1 20.1 25.5 3.6 22.3 33.8 18.4 11.6 19.6 23.6 5.0 11.8 17.6 19.2 14.8 21.9 37.8 10.3 26.6 19.6 13.1 13.4 6.0 12.9 11.5 9.4 14.9 7.7 11.6 11.0 DNM1 DNM ENSG00000106976 "Dynamin 1" Q05193 9 128191655-128255248 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 133.5" "Cell line enhanced" "Detected in many" "A549: 48.8;U-87 MG: 18.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005920, HPA049910, HPA061801" Enhanced Supported Nucleoplasm 440000 Nucleoplasm "CAB005920: , HPA049910: , HPA061801: " "unprognostic (3.25e-2)" "unprognostic (5.49e-2)" "unprognostic (1.34e-3)" "unprognostic (3.95e-2)" "unprognostic (4.57e-2)" "unprognostic (1.16e-1)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (5.53e-2)" "unprognostic (6.53e-2)" "unprognostic (6.62e-3)" "unprognostic (6.30e-1)" "unprognostic (9.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (3.07e-3)" "unprognostic (1.10e-3)" 5.9 6.1 31.5 3.3 36.9 2.3 4.6 57.7 133.5 11.7 3.0 2.5 0.0 2.4 4.6 2.7 3.3 6.3 9.0 2.7 33.4 24.0 2.9 1.8 2.5 2.5 18.3 33.0 1.6 4.7 3.2 5.5 2.7 33.0 2.9 2.9 4.3 2.6 3.1 2.3 4.6 3.3 4.4 5.1 1.6 2.6 4.0 1.8 0.0 1.9 0.4 2.3 3.6 3.7 0.3 0.4 0.5 0.3 0.0 0.3 0.7 3.2 48.8 4.4 1.0 1.4 14.9 0.2 3.0 7.3 6.2 2.6 0.6 1.0 0.0 4.2 6.3 5.8 0.7 0.3 3.4 0.0 4.7 3.1 7.0 0.2 1.0 0.4 2.2 3.9 0.1 4.8 0.0 0.0 1.1 0.2 0.0 1.3 0.2 1.0 4.7 8.9 5.8 0.1 1.5 0.9 0.0 6.3 10.6 10.4 0.3 0.4 0.1 4.2 0.2 0.2 14.1 14.2 6.2 0.4 0.1 0.3 18.6 0.1 1.0 0.0 0.3 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.4 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.7 31.5 36.9 57.7 71.8 33.4 24.0 18.3 33.0 33.0 1.8 DNM1L "DRP1, DVLP, DYMPLE, HDYNIV, VPS1" ENSG00000087470 "Dynamin 1 like" O00429 12 32679200-32745650 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Endocytosis, Necrosis" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009952, HPA039324" Supported Enhanced Vesicles,Cytosol 10000000 Cytosol Vesicles "CAB009952: AB_2093533, HPA039324: " "unprognostic (2.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (5.09e-1)" "unprognostic (4.06e-2)" "prognostic unfavourable (6.27e-6)" "unprognostic (8.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.04e-2)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (7.48e-2)" "unprognostic (1.57e-2)" 15.4 16.2 24.9 14.8 34.4 22.3 14.3 40.5 37.8 13.0 14.5 12.4 14.9 12.3 16.5 16.5 19.8 13.3 11.9 25.4 26.1 28.1 19.4 12.8 11.2 13.8 23.4 23.2 14.1 9.8 28.7 18.8 16.0 27.9 19.3 16.0 12.1 11.1 21.1 25.6 11.8 11.0 21.7 21.7 11.6 12.2 23.1 14.9 13.4 15.2 17.4 15.8 16.9 12.2 5.9 17.0 5.0 14.6 7.2 7.9 7.1 22.1 22.1 23.2 23.8 18.8 19.3 44.9 24.9 19.2 23.5 21.8 31.0 17.0 29.8 17.5 22.5 19.9 24.4 28.6 28.3 15.7 19.9 33.9 21.3 17.0 15.5 24.0 17.9 17.4 14.5 24.9 25.7 28.4 24.5 12.9 26.9 8.6 9.6 20.2 48.9 10.8 16.2 43.7 20.3 19.8 30.5 20.3 20.8 26.5 18.2 19.4 20.9 16.4 25.6 20.1 20.2 47.1 23.1 9.1 24.6 31.1 19.5 16.1 15.2 5.0 9.7 3.1 5.6 14.6 6.8 5.9 6.0 5.9 17.0 5.2 7.3 7.9 1.7 7.2 13.6 5.4 6.1 7.1 24.9 34.4 40.5 37.8 26.1 28.1 23.4 23.2 27.9 14.9 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" 500000 "Golgi apparatus, Cytosol" "HPA054246: " "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favourable (8.91e-4)" "prognostic unfavourable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 23.8 32.6 18.5 29.3 31.2 53.4 20.4 25.7 29.7 20.1 51.4 57.5 46.0 32.1 20.4 16.8 29.9 19.7 27.0 35.0 20.8 18.0 38.5 25.1 39.2 28.2 48.3 18.0 17.9 32.2 19.5 20.0 32.3 32.2 24.0 42.5 24.5 24.7 37.7 46.6 40.6 50.8 18.6 43.1 37.6 48.2 23.3 36.4 39.1 23.5 21.1 41.5 35.7 31.5 3.4 11.1 8.6 9.8 10.1 5.8 4.6 34.9 28.9 21.2 16.9 21.9 21.5 27.2 23.4 22.2 34.7 29.5 28.8 23.1 25.4 42.2 25.2 30.7 28.9 25.4 29.1 31.1 23.0 48.7 25.8 32.2 27.0 26.7 46.3 22.0 19.6 26.5 25.0 33.7 39.1 43.7 21.3 42.3 37.2 25.5 24.1 35.0 37.8 23.0 28.6 22.8 52.7 30.6 20.0 26.7 22.9 16.7 18.4 31.8 30.5 38.1 12.9 53.5 30.9 36.2 36.9 23.4 28.5 40.9 18.8 3.0 4.5 8.6 5.6 8.2 5.1 3.4 4.2 5.8 5.3 3.1 2.4 4.1 8.5 10.1 9.8 11.1 4.8 4.6 18.5 31.2 25.7 29.7 20.8 18.0 48.3 18.0 32.2 36.4 DNM3 KIAA0820 ENSG00000197959 "Dynamin 3" Q9UQ16 1 171841498-172418466 "Enzymes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.3" "Cell line enhanced" "Detected in many" "HEL: 17.9;HMC-1: 8.3;RH-30: 8.1;RPTEC TERT1: 15.5;U-251 MG: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 4.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064121 Approved "Golgi apparatus" "Golgi apparatus" "HPA064121: " "unprognostic (8.21e-2)" "unprognostic (6.80e-3)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (8.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.52e-3)" "unprognostic (6.46e-2)" "unprognostic (5.52e-2)" "unprognostic (2.96e-2)" "unprognostic (2.45e-2)" "unprognostic (3.37e-1)" "unprognostic (6.10e-4)" "unprognostic (1.60e-3)" "unprognostic (1.35e-1)" "unprognostic (2.22e-1)" "unprognostic (2.70e-3)" 5.0 19.3 14.1 2.3 28.3 2.6 3.4 41.4 39.7 6.8 2.7 26.8 0.0 1.9 5.9 3.1 3.0 6.0 5.1 3.0 14.3 16.3 5.8 1.4 7.5 2.5 19.6 17.7 4.6 2.6 3.5 10.3 1.6 47.3 3.6 2.7 2.9 3.7 3.6 2.5 4.0 2.4 5.7 16.4 3.6 5.3 5.4 22.1 0.0 3.4 0.0 2.2 4.3 3.6 0.7 0.7 1.1 0.4 1.0 4.0 3.8 0.6 2.0 1.6 0.3 1.2 0.8 0.0 0.4 1.0 0.8 1.0 0.0 2.9 0.0 6.2 0.9 0.2 1.2 2.3 0.7 0.8 2.3 17.9 3.0 0.0 0.1 0.3 8.3 0.6 0.4 0.9 0.5 0.4 0.0 0.2 0.3 0.0 1.1 0.1 4.7 1.4 1.1 8.1 0.0 15.5 0.1 3.2 0.6 2.1 0.6 0.2 0.0 0.7 0.2 2.3 3.1 1.9 11.1 3.1 0.5 0.1 2.2 0.9 0.8 0.0 0.4 0.0 0.7 0.0 0.9 0.7 1.0 0.5 0.7 0.0 1.2 1.5 1.1 1.0 0.3 0.0 4.0 3.8 14.1 28.3 41.4 31.6 14.3 16.3 19.6 17.7 47.3 22.1 DNMT1 "CXXC9, DNMT, MCMT" ENSG00000130816 "DNA methyltransferase 1" P26358 19 10133345-10231286 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Deafness, Disease mutation, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002694, CAB005876" Enhanced Supported Nucleoplasm Nucleoplasm "CAB005876: AB_731983, HPA002694: AB_1847810" "unprognostic (3.51e-1)" "unprognostic (1.20e-2)" "unprognostic (1.26e-2)" "unprognostic (1.40e-1)" "unprognostic (3.62e-1)" "unprognostic (7.59e-3)" "prognostic unfavourable (1.46e-4)" "unprognostic (2.90e-1)" "unprognostic (4.23e-3)" "unprognostic (1.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.28e-3)" "unprognostic (7.81e-3)" "unprognostic (1.73e-1)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" 12.1 7.6 9.8 20.2 10.8 31.9 11.5 27.1 14.4 12.0 8.6 10.0 4.3 8.1 12.1 8.0 12.0 11.5 7.8 8.0 9.3 8.1 6.9 9.2 11.8 29.7 12.5 7.9 11.1 6.2 10.2 8.8 32.5 8.7 8.3 10.7 7.8 9.3 6.5 6.8 10.8 11.3 11.2 9.1 11.0 9.0 19.9 12.6 31.4 9.5 8.8 28.8 11.4 9.7 12.6 19.0 10.2 13.4 25.0 18.2 6.8 24.0 15.2 19.5 16.5 7.3 7.5 41.8 16.3 13.0 23.5 23.6 14.7 13.1 40.3 10.2 10.0 15.9 21.4 12.7 24.1 15.8 31.9 58.4 13.6 7.6 3.1 23.8 23.7 5.0 2.4 20.5 8.1 12.7 23.1 24.9 17.5 16.0 34.7 32.4 25.5 22.2 35.2 20.4 22.2 7.4 15.3 20.8 16.1 19.8 8.9 6.4 9.3 12.1 9.6 39.5 13.5 23.9 24.1 20.4 21.2 47.7 11.5 22.2 30.6 10.2 13.4 3.3 18.2 13.2 15.9 7.9 14.6 12.5 11.3 12.6 16.6 12.3 3.1 25.0 7.9 19.0 12.9 6.8 9.8 10.8 27.1 14.4 9.3 8.1 12.5 7.9 8.7 12.6 DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 25.5;REH: 25.1;SH-SY5Y: 31.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009469, HPA026588" Approved Supported Nucleoplasm Nucleoplasm "CAB009469: AB_2093990, HPA026588: AB_1847812" "unprognostic (2.38e-1)" "unprognostic (2.94e-1)" "unprognostic (5.65e-2)" "prognostic unfavourable (1.55e-4)" "unprognostic (8.38e-2)" "unprognostic (7.27e-2)" "prognostic unfavourable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "prognostic favourable (1.18e-4)" "unprognostic (2.35e-2)" "prognostic unfavourable (2.49e-4)" "unprognostic (1.43e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-2)" 7.8 12.4 13.7 12.7 15.5 10.8 8.6 21.6 20.1 9.0 12.7 14.5 7.6 9.1 13.0 12.2 8.0 9.6 8.9 8.2 12.3 6.7 9.4 6.9 9.5 13.6 15.3 10.1 18.3 12.1 6.3 12.6 20.8 10.7 9.3 9.2 12.0 8.5 9.2 29.1 6.6 11.4 11.3 7.9 17.5 11.6 6.6 15.2 20.8 9.1 10.5 11.8 9.8 8.4 3.0 4.1 4.9 4.1 8.7 8.3 2.3 1.0 3.5 14.7 3.6 1.6 1.2 19.4 1.0 0.9 2.0 1.6 8.7 5.7 0.0 2.2 1.9 0.9 1.6 2.2 1.2 3.6 2.5 6.3 5.3 10.4 3.8 1.3 4.1 3.6 1.1 2.6 0.9 8.2 7.3 1.3 1.5 8.4 13.8 14.9 25.5 1.9 25.1 16.2 2.1 1.2 1.5 8.8 31.0 1.2 8.4 2.6 0.9 6.7 2.8 2.5 3.2 0.6 1.3 3.1 2.2 8.5 0.9 3.8 2.6 4.7 1.8 3.1 5.2 3.0 7.0 2.3 3.4 4.9 2.0 3.0 8.3 6.6 4.9 8.7 4.1 4.1 2.8 2.3 13.7 15.5 21.6 20.1 12.3 6.7 15.3 10.1 10.7 15.2 DNMT3B ENSG00000088305 "DNA methyltransferase 3 beta" Q9UBC3 20 32762385-32809356 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Activator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.7;testis: 23.3" "Cell line enhanced" "Detected in many" "BEWO: 55.9;CACO-2: 21.0;HEL: 22.0;K-562: 21.1;NB-4: 18.6;NTERA-2: 75.5" "Cancer enriched" "Detected in all" 25 "testis cancer: 111.7" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001595, HPA001803, CAB069896" Enhanced Supported Nucleoplasm Nucleoplasm "CAB069896: AB_2094115, HPA001595: AB_1847814, HPA001803: " "unprognostic (7.65e-3)" "unprognostic (3.52e-3)" "unprognostic (1.17e-1)" "prognostic unfavourable (5.04e-4)" "unprognostic (3.42e-1)" "unprognostic (7.27e-2)" "unprognostic (4.39e-4)" "unprognostic (4.18e-3)" "unprognostic (8.60e-3)" "unprognostic (8.48e-2)" "unprognostic (6.79e-2)" "unprognostic (4.65e-2)" "prognostic unfavourable (1.87e-7)" "unprognostic (6.62e-2)" "unprognostic (1.00e-1)" "unprognostic (1.50e-1)" "unprognostic (6.55e-2)" 1.1 0.8 0.9 2.5 0.9 4.7 2.4 4.5 1.4 1.6 2.1 0.7 0.5 0.9 1.3 4.7 1.6 1.1 1.6 1.8 0.8 0.7 2.7 1.2 1.2 1.9 0.9 0.5 1.2 7.5 2.5 1.1 2.8 0.8 1.1 0.8 1.2 3.5 1.6 0.5 5.5 0.8 1.0 0.5 1.3 1.1 23.3 0.8 17.7 2.6 1.7 2.5 2.7 2.2 0.7 1.0 0.0 0.2 0.9 1.3 0.1 0.8 1.1 6.1 1.4 0.1 0.5 55.9 0.7 0.5 0.8 0.8 21.0 0.9 2.2 2.2 0.3 0.5 3.9 0.3 0.6 0.2 3.1 22.0 0.7 4.0 0.2 0.9 2.2 0.5 0.4 1.2 0.2 1.4 21.1 0.6 0.3 3.4 3.3 18.6 75.5 0.7 3.3 1.0 0.5 2.0 0.9 1.9 1.3 1.3 1.9 0.5 1.3 1.2 0.3 1.2 2.8 0.6 0.5 1.3 0.6 0.8 0.6 6.0 0.5 0.0 0.2 0.0 0.1 0.1 0.1 0.7 0.2 0.0 1.0 0.0 1.3 0.0 0.0 0.9 0.1 0.9 0.0 0.1 0.9 0.9 4.5 1.4 0.8 0.7 0.9 0.5 0.8 0.8 DNPEP "ASPEP, DAP" ENSG00000123992 "Aspartyl aminopeptidase" Q9ULA0 2 219373527-219400022 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036398, HPA044860" Enhanced Supported Cytosol 6200000 Cytosol "HPA036398: AB_10970915, HPA044860: AB_10961275" "unprognostic (3.71e-1)" "unprognostic (6.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.75e-1)" "unprognostic (2.54e-3)" "unprognostic (3.34e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" "unprognostic (1.61e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-1)" "unprognostic (5.63e-3)" "unprognostic (3.49e-1)" "unprognostic (2.50e-1)" "unprognostic (1.85e-3)" 20.1 12.3 8.8 15.5 10.4 7.2 20.0 7.2 9.3 16.5 30.4 8.6 13.8 27.9 15.1 13.3 16.9 15.3 16.6 22.9 10.4 6.8 21.2 33.5 15.5 11.7 10.5 7.2 19.4 19.0 9.7 11.0 28.5 9.4 21.0 15.8 15.9 18.7 14.7 36.6 14.6 50.3 12.9 6.8 17.5 15.2 33.7 9.3 11.3 15.0 20.0 17.4 20.7 13.1 11.6 16.1 5.8 15.0 15.7 15.7 10.9 16.0 8.8 5.4 16.1 14.4 11.9 43.0 8.0 16.2 20.9 22.1 24.3 21.2 9.8 17.3 16.6 15.8 6.5 18.3 7.6 19.2 4.6 15.9 9.0 26.4 38.2 13.1 11.4 19.3 19.5 21.5 18.0 14.3 17.9 15.8 10.7 34.9 20.0 14.6 8.9 5.5 26.0 12.4 12.9 11.6 25.0 6.8 9.2 9.3 30.8 11.3 9.0 14.5 7.9 20.1 16.6 10.5 11.5 17.7 10.3 7.0 28.6 12.6 8.5 5.8 13.2 5.4 13.6 15.0 15.4 10.2 11.0 15.0 16.1 11.6 12.0 15.7 1.0 15.7 12.2 5.8 12.6 10.9 8.8 10.4 7.2 9.3 10.4 6.8 10.5 7.2 9.4 9.3 DNTT TDT ENSG00000107447 "DNA nucleotidylexotransferase" P04053 10 96304396-96338564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Terminal addition" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 171.0" "Group enriched" "Detected in some" 420 "MOLT-4: 48.7;REH: 168.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "naive B-cell: 1.2;naive CD4 T-cell: 4.5" "Group enriched" "Detected in many" 15 "B-cells: 1.2;T-cells: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036532, HPA044194" Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA036532: , HPA044194: AB_10960525" "unprognostic (4.24e-1)" "unprognostic (1.00e-1)" "unprognostic (2.60e-2)" "unprognostic (1.86e-2)" 0.0 0.0 0.1 0.1 0.3 24.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 2.7 0.0 171.0 0.6 0.0 2.1 0.0 0.0 1.2 0.1 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 168.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 DOHH "HLRC1, MGC4293" ENSG00000129932 "Deoxyhypusine hydroxylase" Q9BU89 19 3490822-3500940 "Enzymes, Predicted intracellular proteins" "Hypusine biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041953, HPA076271" Approved Approved Nucleoplasm,Nucleoli,Cytosol Cytosol "Nucleoplasm, Nucleoli" "HPA041953: AB_10795386, HPA076271: " "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" "unprognostic (8.63e-2)" "prognostic favourable (2.24e-4)" "unprognostic (3.66e-1)" "unprognostic (2.01e-2)" "unprognostic (9.45e-2)" "unprognostic (7.26e-2)" "unprognostic (4.65e-2)" "unprognostic (1.13e-1)" "prognostic favourable (3.58e-4)" "unprognostic (9.87e-3)" "unprognostic (1.14e-3)" "unprognostic (4.35e-2)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" "unprognostic (3.76e-3)" 8.1 6.5 10.5 6.6 13.0 9.3 3.4 5.5 13.0 3.9 5.5 6.9 2.6 18.9 3.7 4.1 4.1 3.1 4.9 5.1 14.9 9.1 6.0 6.4 4.0 4.5 18.2 6.2 3.8 7.6 3.8 3.9 3.8 8.4 5.1 2.0 3.2 6.0 4.0 23.1 7.0 12.3 2.4 25.5 5.9 7.3 4.2 6.1 4.7 2.9 7.8 4.5 3.1 4.7 11.6 11.0 1.8 6.6 6.9 12.3 4.4 9.1 11.0 1.7 3.6 0.9 1.0 7.3 8.7 1.8 4.3 3.4 15.2 3.8 7.2 6.8 1.3 9.5 2.7 3.0 0.9 10.5 12.3 7.5 6.2 18.1 3.5 9.9 10.4 1.2 3.0 4.1 1.8 2.2 16.2 8.5 1.7 10.4 10.8 11.3 9.7 14.8 12.2 4.0 10.3 2.6 5.1 10.4 7.7 6.1 5.4 8.7 7.5 5.5 5.0 5.4 7.4 14.2 15.9 11.3 8.1 9.5 6.4 22.6 6.4 1.1 5.3 1.8 6.2 6.2 8.1 8.1 8.5 12.3 8.7 11.6 12.3 10.4 0.3 6.9 6.6 11.0 9.6 4.4 10.5 13.0 5.5 13.0 14.9 9.1 18.2 6.2 8.4 6.1 DOLK "DK1, KIAA1094, TMEM15" ENSG00000175283 "Dolichol kinase" Q9UPQ8 9 128945530-128947619 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066767, HPA068706" Enhanced Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Nucleoli" Cytosol "HPA066767: , HPA068706: " "unprognostic (6.35e-2)" "unprognostic (2.69e-1)" "unprognostic (2.63e-1)" "unprognostic (1.30e-3)" "unprognostic (3.55e-1)" "unprognostic (2.81e-3)" "unprognostic (8.90e-3)" "unprognostic (3.26e-1)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.83e-2)" "prognostic favourable (5.53e-4)" "unprognostic (3.20e-2)" "unprognostic (1.06e-1)" "prognostic favourable (6.88e-5)" "unprognostic (6.13e-3)" 11.0 20.2 7.9 7.8 13.8 1.4 9.5 7.0 18.6 9.8 8.6 14.9 7.1 8.8 12.4 16.8 10.9 10.8 10.8 12.0 7.6 9.9 17.5 22.0 10.6 10.6 8.1 6.7 13.2 16.9 19.2 8.0 19.5 16.3 12.3 8.0 14.2 15.5 12.8 7.9 11.4 10.9 11.1 5.9 11.6 12.4 22.4 6.0 12.5 11.0 11.9 12.1 10.4 7.3 9.4 14.2 5.6 16.4 9.8 13.7 9.0 5.1 19.1 6.8 10.0 20.1 10.6 9.2 10.7 17.4 13.2 9.8 15.0 8.1 2.8 5.7 15.5 36.4 9.2 13.4 6.8 4.7 8.1 3.5 13.1 10.8 20.3 3.8 6.3 14.6 12.4 14.2 7.8 12.8 8.5 4.5 14.2 25.2 3.1 3.2 8.7 11.9 3.1 9.0 11.1 11.8 7.7 6.2 7.0 14.2 11.7 6.3 20.5 5.0 10.6 11.9 4.3 14.9 8.8 4.3 10.7 2.8 11.2 3.5 9.0 2.3 13.5 5.6 10.2 13.3 9.1 9.4 9.2 11.2 14.2 9.2 12.1 12.3 2.1 9.8 16.4 8.1 13.7 9.0 7.9 13.8 7.0 18.6 7.6 9.9 8.1 6.7 16.3 6.0 DOLPP1 LSFR2 ENSG00000167130 "Dolichyldiphosphatase 1" Q86YN1 9 129081100-129090438 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019179 Approved Approved "Vesicles,Intermediate filaments" Vesicles "Intermediate filaments" "HPA019179: AB_1847827" "unprognostic (1.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.89e-1)" "unprognostic (6.12e-3)" "unprognostic (3.11e-1)" "unprognostic (2.63e-2)" "unprognostic (3.18e-1)" "unprognostic (3.10e-2)" "unprognostic (6.96e-2)" "unprognostic (7.12e-2)" "unprognostic (1.65e-1)" "unprognostic (4.37e-3)" "unprognostic (7.59e-3)" "unprognostic (2.38e-2)" "unprognostic (1.35e-1)" "unprognostic (4.69e-2)" "unprognostic (5.34e-2)" 6.4 12.8 10.0 6.8 10.6 7.7 6.8 11.7 19.3 8.3 17.1 17.7 8.6 28.6 6.0 7.4 18.8 6.6 9.2 4.1 10.1 10.7 9.4 21.8 6.7 6.6 13.2 10.6 7.7 10.5 10.4 6.9 11.6 12.5 10.0 14.2 6.1 10.3 5.8 5.2 10.3 27.7 6.3 15.2 8.5 11.8 12.2 11.0 9.4 6.3 8.5 9.1 7.8 8.0 8.8 12.5 9.8 8.3 7.9 21.7 7.2 4.3 16.6 16.3 14.9 5.5 4.7 18.9 10.7 6.2 20.3 11.3 21.3 14.4 8.3 9.4 6.6 31.3 16.7 8.9 8.6 9.8 10.3 11.0 11.2 16.3 9.7 11.3 13.7 5.0 12.5 13.3 10.6 9.0 18.1 8.4 5.7 21.8 13.0 11.8 14.0 13.5 15.3 13.2 15.0 7.4 7.0 18.6 12.2 13.4 12.3 4.5 22.5 7.5 7.4 17.5 8.4 16.4 14.4 10.5 20.0 12.7 7.7 2.3 11.5 4.4 6.8 9.8 8.9 8.1 21.7 8.8 10.9 10.8 8.5 6.0 11.1 10.5 1.4 7.9 8.3 12.5 10.1 7.2 10.0 10.6 11.7 19.3 10.1 10.7 13.2 10.6 12.5 11.0 DOT1L "DOT1, KIAA1814, KMT4" ENSG00000104885 "DOT1 like histone lysine methyltransferase" Q8TEK3 19 2164149-2232578 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 64.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011875, HPA071217, HPA074977" Approved Enhanced Nucleoplasm Nucleoplasm "HPA011875: , HPA071217: , HPA074977: " "unprognostic (1.41e-2)" "unprognostic (1.44e-1)" "unprognostic (2.26e-1)" "prognostic favourable (1.69e-4)" "unprognostic (1.08e-1)" "prognostic favourable (6.00e-4)" "unprognostic (2.53e-3)" "unprognostic (2.21e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-2)" "unprognostic (5.25e-3)" "unprognostic (8.18e-3)" "unprognostic (2.56e-1)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" 7.3 8.8 7.0 10.7 11.7 20.1 5.1 20.6 11.7 4.5 7.9 9.8 6.0 13.5 6.4 4.9 8.3 5.4 6.9 5.7 7.0 3.6 9.5 8.5 10.0 8.4 11.9 5.3 6.5 10.8 3.6 8.3 11.6 7.1 5.7 4.9 9.5 6.1 7.4 9.8 9.9 13.0 4.2 6.7 10.4 13.3 64.7 9.7 10.5 9.2 7.0 9.1 4.8 5.3 0.7 1.0 3.0 0.9 2.8 1.4 0.6 12.0 6.5 22.1 12.1 1.6 2.4 29.1 6.9 1.5 3.8 3.0 8.3 4.5 14.2 3.3 4.4 10.9 7.3 3.8 1.8 7.2 9.2 13.1 10.6 8.1 2.7 18.6 24.1 2.4 2.9 7.3 3.7 3.1 15.8 14.9 2.9 6.9 14.9 20.6 17.1 11.6 15.4 6.3 9.7 2.1 5.7 14.8 11.4 4.8 14.4 9.1 6.6 14.3 4.4 10.6 9.6 15.6 13.2 13.8 18.0 9.8 10.5 12.9 6.1 0.5 0.7 3.0 0.9 0.3 1.4 0.7 0.8 0.2 0.9 0.7 0.5 0.3 0.3 2.8 0.9 1.0 0.1 0.6 7.0 11.7 20.6 11.7 7.0 3.6 11.9 5.3 7.1 9.7 DPAGT1 "ALG7, CDG-Ij, D11S366, DGPT, DPAGT, DPAGT2, GPT" ENSG00000172269 "Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1" Q9H3H5 11 119096503-119108331 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053878 Approved "HPA053878: " "unprognostic (1.66e-2)" "unprognostic (3.14e-3)" "unprognostic (1.76e-1)" "unprognostic (7.83e-3)" "unprognostic (6.50e-2)" "unprognostic (8.53e-3)" "prognostic unfavourable (2.03e-5)" "unprognostic (2.52e-1)" "unprognostic (3.95e-1)" "unprognostic (9.05e-2)" "unprognostic (2.08e-2)" "unprognostic (7.12e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (1.08e-2)" "unprognostic (2.52e-2)" "unprognostic (4.57e-2)" 13.0 20.0 6.8 9.7 6.7 5.5 10.0 5.2 9.3 13.2 13.1 8.5 13.0 11.0 10.9 12.0 14.5 11.6 11.3 8.3 5.9 5.8 12.5 53.0 10.0 6.9 7.5 3.6 11.6 32.1 18.4 5.8 12.5 7.4 10.6 11.1 8.1 26.3 13.6 8.0 6.9 15.3 10.6 6.4 12.2 11.9 5.4 8.0 7.7 11.8 7.2 12.4 16.1 8.3 10.1 16.4 9.2 14.4 7.6 11.8 8.0 5.5 14.0 4.9 15.1 18.9 11.3 6.7 10.1 10.6 6.8 10.2 13.7 23.5 11.8 16.0 14.4 18.0 13.7 18.4 7.8 6.5 7.5 21.0 4.5 16.7 15.6 13.3 10.5 14.5 15.4 18.5 25.8 15.8 13.0 22.9 15.3 17.6 3.2 8.1 5.6 15.7 5.4 6.7 16.5 17.6 13.1 6.6 6.7 7.4 24.9 4.1 33.5 5.5 8.0 16.9 6.4 7.5 5.3 3.3 8.7 3.8 3.2 17.1 13.1 9.2 14.4 1.4 9.8 13.2 11.8 10.1 7.5 9.7 16.4 7.3 6.0 6.0 1.4 7.6 11.5 15.2 6.7 8.0 6.8 6.7 5.2 9.3 5.9 5.8 7.5 3.6 7.4 8.0 DPEP1 ENSG00000015413 "Dipeptidase 1" P16444 16 89613308-89638456 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "intestine: 161.7;kidney: 52.2;pancreas: 100.5" "Cell line enhanced" "Detected in some" "CACO-2: 5.1;Hep G2: 19.9;HHSteC: 9.0;U-937: 28.3" "Cancer enriched" "Detected in many" 8 "colorectal cancer: 107.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009426, HPA012783" Enhanced Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" 270000 "Nucleoplasm, Cell Junctions" "HPA009426: AB_1847842, HPA012783: AB_1847843" "unprognostic (3.31e-2)" "unprognostic (3.86e-1)" "unprognostic (1.37e-1)" "unprognostic (1.95e-2)" "unprognostic (1.91e-2)" "unprognostic (4.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (3.45e-2)" "unprognostic (5.18e-1)" "unprognostic (8.68e-2)" "unprognostic (1.27e-1)" "prognostic favourable (6.84e-4)" "unprognostic (6.12e-3)" "unprognostic (1.92e-1)" "unprognostic (5.23e-2)" "unprognostic (3.93e-2)" 0.1 0.4 0.1 0.9 0.1 0.0 0.1 0.1 0.1 1.5 53.6 0.1 0.4 16.1 0.2 3.4 0.3 0.1 0.9 0.1 0.1 0.1 52.2 0.1 0.3 0.9 0.1 0.1 0.2 100.5 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.3 0.4 0.1 0.4 161.7 0.1 0.1 0.9 0.2 9.8 0.1 0.2 0.1 0.1 0.5 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.0 1.1 0.1 2.8 0.0 0.0 0.0 0.0 5.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 19.9 9.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 DPEP2 ENSG00000167261 "Dipeptidase 2" Q9H4A9 16 67987394-68000586 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 105.1" "Cell line enhanced" "Detected in some" "HEL: 4.3;HMC-1: 19.5;NB-4: 4.2;U-937: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 43.5;eosinophil: 105.1;neutrophil: 47.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 105.1" "Low region specificity" "Detected in many" HPA035644 Approved 260000000 "HPA035644: AB_10670164" "unprognostic (8.81e-2)" "unprognostic (7.84e-5)" "unprognostic (1.35e-1)" "unprognostic (1.42e-2)" "unprognostic (1.92e-1)" "unprognostic (6.66e-3)" "unprognostic (1.03e-1)" "unprognostic (5.47e-2)" "unprognostic (3.69e-2)" "unprognostic (1.68e-1)" "unprognostic (6.01e-2)" "unprognostic (1.46e-1)" "unprognostic (3.91e-2)" "unprognostic (5.75e-2)" "prognostic unfavourable (8.47e-4)" "unprognostic (7.78e-3)" "unprognostic (3.91e-2)" 7.8 0.9 1.3 7.1 2.4 13.0 3.5 0.7 2.5 1.5 2.6 2.4 1.1 1.7 4.1 4.1 1.8 2.0 6.8 2.4 1.6 1.3 2.0 2.0 11.4 10.4 2.1 2.0 0.7 0.9 0.1 0.9 19.4 2.7 2.4 2.4 5.1 2.8 0.4 1.6 1.2 10.1 2.3 3.3 26.4 1.6 2.5 1.6 3.5 2.5 3.8 11.1 6.3 1.5 5.0 4.3 105.1 15.3 5.6 4.9 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.3 0.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 4.3 0.0 0.1 0.0 0.1 19.5 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 4.2 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.0 1.1 0.5 0.3 0.0 6.5 0.0 43.5 10.7 105.1 2.3 13.0 2.7 4.1 4.0 1.9 4.3 5.0 4.9 2.5 47.3 5.6 15.3 0.6 4.0 5.7 1.3 2.4 0.7 2.5 1.6 1.3 2.1 2.0 2.7 1.6 DPEP3 ENSG00000141096 "Dipeptidase 3" Q9H4B8 16 67975663-67980829 "Enzymes, Predicted intracellular proteins" Meiosis "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 56.7" "Cell line enriched" "Detected in single" 11 "U-266/70: 4.8" "Group enriched" "Detected in many" 10 "melanoma: 3.7;ovarian cancer: 16.9;testis cancer: 5.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 9.2;NK-cell: 2.3" "Group enriched" "Detected in many" 7 "granulocytes: 9.2;NK-cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031870, HPA058607" Enhanced "Intracellular and membrane" 16000000 "HPA031870: AB_2674079, HPA058607: AB_2683775" "unprognostic (9.93e-2)" "unprognostic (2.81e-3)" "unprognostic (1.86e-1)" "unprognostic (9.52e-2)" "unprognostic (3.61e-2)" "unprognostic (1.37e-2)" "unprognostic (1.55e-1)" "unprognostic (6.52e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.49e-3)" "unprognostic (9.97e-2)" "unprognostic (1.56e-1)" "unprognostic (3.15e-3)" "unprognostic (1.13e-1)" "unprognostic (3.98e-2)" "unprognostic (1.51e-1)" 0.2 0.0 0.1 0.4 0.4 1.0 0.6 0.1 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.6 0.0 0.3 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.0 0.2 0.3 0.1 0.1 0.0 0.5 0.0 0.4 1.4 0.2 56.7 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.8 0.1 9.2 0.5 2.3 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.2 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.5 0.3 0.4 0.0 0.0 0.1 0.8 0.8 0.3 9.2 2.3 0.1 0.0 0.0 0.3 0.1 0.4 0.1 0.3 0.3 0.1 0.1 0.0 0.9 0.1 DPH1 "DPH2L, DPH2L1, OVCA1" ENSG00000108963 "Diphthamide biosynthesis 1" Q9BZG8 17 2030110-2043430 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation, Dwarfism, Ectodermal dysplasia, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069750, HPA073864" Approved Approved "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "HPA069750: , HPA073864: " "unprognostic (5.54e-2)" "unprognostic (1.99e-1)" "unprognostic (1.62e-1)" "unprognostic (1.86e-2)" "unprognostic (1.50e-2)" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "prognostic favourable (1.78e-5)" "unprognostic (2.74e-3)" "unprognostic (2.10e-2)" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (7.30e-2)" "unprognostic (1.41e-1)" 16.6 22.9 17.6 19.0 22.7 10.3 17.0 38.6 26.5 17.8 17.1 17.2 21.1 17.0 22.2 17.0 17.9 29.0 22.6 20.2 14.1 13.1 21.4 32.7 15.7 22.7 17.0 21.6 25.2 29.4 28.4 42.9 17.3 15.4 26.1 13.3 21.3 25.7 23.9 33.3 29.0 17.3 18.9 11.4 17.8 18.4 19.5 19.9 17.5 21.0 25.8 19.0 17.2 16.0 11.3 9.3 0.7 6.8 5.6 12.0 5.5 9.0 15.8 4.3 10.6 13.6 9.9 11.9 11.9 17.9 20.3 13.2 15.1 7.4 17.6 15.4 35.2 7.2 14.5 13.4 11.0 4.6 33.3 4.1 7.4 9.0 12.9 5.1 6.7 14.9 13.7 16.2 13.2 9.1 13.8 7.2 7.9 11.9 9.0 3.3 4.0 16.2 10.4 3.1 13.6 9.0 5.6 8.2 9.5 10.8 12.2 11.9 17.8 4.2 6.3 14.2 6.5 17.4 10.7 7.2 5.0 4.3 13.9 7.0 4.9 0.0 4.6 0.7 9.5 6.8 10.4 11.3 7.8 8.6 9.3 9.5 12.0 8.7 0.3 5.6 4.6 6.7 10.4 5.5 17.6 22.7 38.6 26.5 14.1 13.1 17.0 21.6 15.4 19.9 DPH2 DPH2L2 ENSG00000132768 "DPH2 homolog" Q9BQC3 1 43970000-43973369 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045796 Uncertain Approved Nucleoplasm Nucleoplasm "HPA045796: " "unprognostic (2.41e-1)" "unprognostic (1.15e-1)" "unprognostic (4.20e-3)" "unprognostic (9.13e-3)" "unprognostic (3.83e-2)" "unprognostic (1.30e-1)" "prognostic unfavourable (1.17e-8)" "unprognostic (1.38e-1)" "unprognostic (1.81e-1)" "unprognostic (3.72e-1)" "unprognostic (2.49e-1)" "unprognostic (3.42e-3)" "unprognostic (2.60e-1)" "prognostic favourable (1.37e-4)" "unprognostic (1.38e-1)" "unprognostic (2.41e-2)" "unprognostic (6.37e-2)" 9.6 12.7 13.5 12.4 14.1 7.5 9.8 7.9 18.8 8.3 12.0 12.4 5.9 8.9 9.4 7.5 15.2 10.8 11.5 11.6 11.6 6.3 11.5 21.7 8.5 14.1 13.6 9.3 9.1 21.1 10.4 10.6 8.3 9.7 9.8 11.9 5.8 11.6 9.2 33.4 13.1 9.9 11.2 7.6 13.7 10.6 14.7 12.3 10.8 8.9 14.6 13.5 10.3 7.8 9.0 10.2 0.5 9.2 9.8 10.1 5.8 9.8 11.4 5.1 10.9 3.9 4.1 17.4 5.3 5.7 13.8 11.2 14.5 9.7 16.6 9.0 5.4 11.4 17.2 15.0 7.4 11.4 15.0 17.1 14.2 14.9 10.2 19.7 9.7 6.3 16.7 16.2 9.0 9.5 21.6 9.4 6.8 11.5 17.4 10.9 35.5 13.1 15.0 11.8 27.0 8.6 7.9 17.7 20.5 7.0 17.6 12.8 7.4 13.7 6.2 6.6 15.2 11.7 20.9 23.0 38.1 17.1 5.9 22.0 9.7 0.0 6.6 0.3 6.7 9.2 9.9 9.0 6.8 6.9 10.2 8.8 7.0 10.1 0.5 9.8 4.7 8.5 6.6 5.8 13.5 14.1 7.9 18.8 11.6 6.3 13.6 9.3 9.7 12.3 DPH5 CGI-30 ENSG00000117543 "Diphthamide biosynthesis 5" Q9H2P9 1 100989623-101026088 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046439, HPA076234" Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA046439: , HPA076234: " "unprognostic (1.31e-1)" "unprognostic (3.37e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (3.57e-2)" "unprognostic (8.59e-2)" "unprognostic (8.12e-2)" "unprognostic (1.37e-2)" "unprognostic (2.56e-1)" "unprognostic (1.58e-2)" "unprognostic (2.15e-1)" "unprognostic (7.09e-2)" "unprognostic (1.88e-1)" "unprognostic (9.00e-2)" 12.6 21.5 11.2 9.1 19.0 7.9 21.4 10.4 11.9 17.3 12.8 11.5 13.2 6.8 20.6 19.0 16.1 19.3 10.0 19.2 11.2 11.9 14.1 18.1 8.5 15.2 11.9 11.4 39.0 28.4 15.5 31.7 9.3 12.3 15.3 13.7 10.8 16.1 12.7 16.8 11.5 9.2 15.4 16.7 13.6 11.5 9.2 11.3 22.2 18.4 15.5 17.7 14.4 14.7 12.1 8.4 3.3 6.2 14.9 16.2 6.7 9.5 8.7 13.0 12.7 16.0 45.7 11.2 8.5 13.8 12.3 10.4 10.4 2.4 16.8 11.2 7.1 6.2 14.4 12.8 18.2 7.0 10.6 8.8 8.4 19.6 25.0 10.7 4.7 30.6 18.7 11.5 37.5 18.4 19.7 5.3 18.6 8.2 13.0 10.5 10.5 13.6 12.1 18.9 9.6 13.9 7.3 15.0 7.3 4.6 12.9 37.3 8.4 6.4 9.3 7.3 10.3 10.6 11.1 6.3 7.3 10.3 10.0 10.1 2.7 3.3 5.1 2.6 11.1 5.5 15.1 12.1 12.3 12.1 8.4 9.6 16.2 14.8 1.9 14.9 6.2 6.2 8.2 6.7 11.2 19.0 10.4 11.9 11.2 11.9 11.9 11.4 12.3 11.3 DPH6 "ATPBD4, MGC14798" ENSG00000134146 "Diphthamine biosynthesis 6" Q7L8W6 15 35217345-35546193 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042976, HPA055496" Approved Enhanced Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA042976: AB_10964890, HPA055496: " "unprognostic (9.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.92e-1)" "unprognostic (1.14e-1)" "unprognostic (1.82e-1)" "unprognostic (1.45e-2)" "unprognostic (1.60e-1)" "unprognostic (9.94e-2)" "unprognostic (1.76e-1)" "unprognostic (1.49e-3)" "unprognostic (7.92e-3)" "unprognostic (1.13e-1)" "unprognostic (4.65e-6)" "unprognostic (9.70e-2)" "unprognostic (5.61e-2)" "unprognostic (2.18e-2)" "unprognostic (7.44e-2)" 13.3 12.7 8.0 6.8 16.1 6.4 15.3 11.6 15.8 14.7 9.2 15.5 10.8 8.5 23.9 17.1 14.7 11.5 10.5 14.4 7.8 7.2 14.7 11.2 8.7 9.3 9.7 12.0 16.7 19.5 15.8 31.7 11.1 13.4 8.5 10.2 14.6 11.5 14.7 24.9 15.2 8.7 16.8 11.1 8.3 9.6 11.3 10.6 7.1 15.3 16.5 10.0 11.0 11.3 8.4 6.3 0.3 6.5 13.2 10.8 4.4 10.5 5.6 9.5 8.1 1.7 7.9 9.3 4.0 7.0 9.7 5.0 7.6 9.9 3.2 9.7 3.6 12.1 11.0 11.4 11.6 2.5 6.9 12.2 6.5 11.9 10.2 6.5 7.9 6.6 14.5 3.8 18.7 9.2 13.4 13.3 8.8 4.1 8.0 6.1 8.4 5.2 9.9 8.9 4.5 8.3 13.4 7.0 6.8 7.4 8.4 6.4 28.8 9.1 2.8 9.4 9.2 9.4 6.3 12.0 18.8 8.2 8.1 11.2 8.9 0.0 6.5 0.3 6.2 6.0 7.7 8.4 8.3 8.6 6.3 6.5 10.8 9.5 0.3 13.2 5.6 5.4 5.4 4.4 8.0 16.1 11.6 15.8 7.8 7.2 9.7 12.0 13.4 10.6 DPH7 "C9orf112, FLJ90634, RRT2, WDR85" ENSG00000148399 "Diphthamide biosynthesis 7" Q9BTV6 9 137554904-137578935 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022911 Uncertain Approved "Nuclear bodies" "Nuclear bodies" "HPA022911: AB_1858823" "unprognostic (1.43e-1)" "unprognostic (4.81e-2)" "unprognostic (3.41e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-1)" "unprognostic (6.60e-3)" "unprognostic (1.48e-2)" "unprognostic (1.78e-1)" "unprognostic (2.14e-2)" "unprognostic (9.48e-2)" "prognostic favourable (6.52e-4)" "unprognostic (2.10e-2)" "prognostic unfavourable (1.52e-5)" "unprognostic (2.30e-3)" "unprognostic (3.06e-2)" "unprognostic (2.15e-1)" "prognostic favourable (3.23e-4)" 8.2 12.7 12.1 14.0 16.4 8.2 10.7 15.9 17.8 13.3 12.7 21.5 14.3 5.9 14.2 17.8 9.4 18.2 10.3 12.6 14.0 7.6 11.1 11.0 10.4 13.0 19.1 11.5 17.3 20.8 14.1 14.9 10.5 12.8 15.6 11.9 10.8 16.1 15.4 9.6 13.5 12.2 14.6 9.0 16.0 11.8 10.1 18.6 11.2 13.8 5.8 13.9 10.9 11.7 10.8 14.2 15.6 9.2 9.3 13.5 8.8 7.4 7.8 12.7 11.4 9.2 7.0 14.7 7.4 7.2 12.5 10.7 15.5 7.5 14.6 13.4 7.8 17.9 14.8 12.6 10.0 11.8 17.2 6.2 10.5 5.6 10.4 13.8 13.2 7.2 11.3 8.3 15.9 16.6 12.3 7.8 8.7 21.1 10.4 15.1 14.7 16.6 18.7 6.7 11.9 10.4 7.0 14.5 13.2 11.4 9.7 8.3 14.0 13.7 7.9 9.9 8.0 11.4 14.2 6.4 12.5 16.3 5.1 9.5 9.3 15.6 8.9 9.7 10.9 9.2 11.6 10.8 13.5 12.7 10.4 9.5 11.5 11.7 2.3 9.3 6.4 14.2 9.3 8.8 12.1 16.4 15.9 17.8 14.0 7.6 19.1 11.5 12.8 18.6 DPM1 "CDGIE, MPDS" ENSG00000000419 "Dolichyl-phosphate mannosyltransferase subunit 1, catalytic" O60762 20 50934867-50958555 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051818 Approved "HPA051818: " "unprognostic (2.21e-2)" "unprognostic (4.94e-2)" "unprognostic (1.16e-1)" "unprognostic (4.24e-3)" "unprognostic (1.65e-1)" "unprognostic (3.27e-2)" "prognostic unfavourable (1.94e-6)" "unprognostic (1.10e-1)" "unprognostic (7.49e-2)" "unprognostic (2.53e-2)" "unprognostic (1.29e-2)" "unprognostic (3.61e-2)" "unprognostic (3.02e-3)" "unprognostic (4.98e-2)" "unprognostic (2.59e-1)" "unprognostic (3.58e-1)" "unprognostic (2.74e-1)" 32.3 39.7 20.2 23.3 30.0 32.9 29.0 22.5 35.1 31.1 28.1 21.3 28.9 24.0 29.9 32.9 36.0 25.6 24.0 38.7 22.2 21.5 41.7 54.0 24.2 33.0 21.6 17.2 30.8 38.9 21.2 35.1 43.9 31.4 29.8 28.9 22.8 35.9 31.5 44.7 27.1 35.6 24.9 21.1 38.6 30.4 25.6 21.7 36.1 34.5 49.1 36.4 35.3 28.3 20.7 25.0 22.2 19.6 20.3 25.1 15.7 34.6 14.1 21.8 13.0 19.0 21.6 23.9 13.8 15.8 26.7 21.1 63.5 28.2 21.2 30.1 17.8 39.9 17.4 32.7 27.2 10.1 13.9 22.0 18.3 42.7 27.1 34.8 13.2 18.5 48.3 18.5 19.3 20.3 33.1 26.9 26.5 15.3 31.5 36.8 22.3 32.2 17.5 31.9 28.0 26.6 21.1 16.4 17.9 35.6 52.6 46.0 35.8 41.3 16.8 34.3 28.5 20.1 28.3 19.2 24.3 30.4 37.8 23.3 15.5 12.2 16.8 18.6 19.0 19.6 23.0 20.7 21.8 20.3 21.9 19.3 23.7 25.1 22.2 20.3 18.9 25.0 21.0 15.7 20.2 30.0 22.5 35.1 22.2 21.5 21.6 17.2 31.4 21.7 DPP10 "DPL2, DPPY, DPRP3" ENSG00000175497 "Dipeptidyl peptidase like 10" Q8N608 2 114442299-115845752 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 15.6;brain: 30.3;pancreas: 23.4" "Cell line enhanced" "Detected in some" "AF22: 5.0;HAP1: 7.5;HMC-1: 5.3;NTERA-2: 4.5;RT4: 8.0;SCLC-21H: 11.9;SH-SY5Y: 4.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048767 Uncertain "HPA048767: " "unprognostic (1.19e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (6.59e-2)" "unprognostic (2.92e-1)" "unprognostic (5.35e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (8.33e-2)" "unprognostic (7.61e-2)" "unprognostic (4.22e-2)" 0.7 15.6 13.4 1.1 15.9 0.9 0.9 1.9 30.3 1.3 3.6 7.9 0.0 2.4 1.4 0.8 0.8 0.9 1.9 0.8 17.5 9.9 1.1 0.9 1.0 0.7 7.1 21.3 0.9 23.4 0.7 1.5 1.8 10.8 0.8 4.6 0.0 1.0 0.8 0.7 0.9 2.4 1.9 12.7 0.7 1.5 2.1 10.3 0.0 1.6 0.0 0.8 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 8.0 11.9 4.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 15.9 1.9 30.3 17.5 9.9 7.1 21.3 10.8 10.3 DPP3 ENSG00000254986 "Dipeptidyl peptidase 3" Q9NY33 11 66480013-66509657 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035780, HPA035781" Approved Supported Cytosol 2600000 Cytosol "HPA035780: AB_2674778, HPA035781: AB_10669529" "unprognostic (5.74e-2)" "unprognostic (1.16e-3)" "unprognostic (2.62e-3)" "unprognostic (4.77e-2)" "unprognostic (1.99e-1)" "unprognostic (5.44e-3)" "unprognostic (1.67e-3)" "unprognostic (1.25e-3)" "unprognostic (1.73e-2)" "unprognostic (9.87e-2)" "unprognostic (1.02e-2)" "unprognostic (3.87e-1)" "unprognostic (5.85e-2)" "prognostic favourable (1.34e-4)" "unprognostic (1.81e-2)" "unprognostic (3.43e-1)" "unprognostic (5.66e-2)" 10.4 13.0 5.2 16.8 12.1 10.9 16.9 13.7 11.5 7.3 18.5 9.1 10.3 15.3 10.5 6.8 15.6 7.1 15.7 8.4 9.3 5.9 18.4 31.1 9.8 20.0 9.5 10.6 5.1 11.6 11.2 6.9 10.9 7.4 10.3 16.9 5.7 17.6 8.5 15.8 9.4 15.5 10.0 10.6 12.5 11.8 15.5 6.7 16.1 10.5 10.8 14.0 11.4 8.6 7.5 19.7 12.2 24.4 18.2 17.9 9.9 28.5 24.8 11.5 12.8 9.6 10.4 17.9 16.2 21.8 21.9 14.6 31.2 24.0 16.6 55.2 18.3 25.7 18.3 19.8 14.1 31.5 8.3 21.6 11.6 18.3 14.8 26.1 36.1 14.7 19.4 16.4 8.2 16.7 15.1 9.9 19.9 32.4 30.4 26.6 19.6 15.2 21.5 11.6 27.2 18.8 24.6 21.8 18.7 13.8 16.1 21.6 25.0 15.3 17.4 13.1 14.3 14.4 15.8 8.3 15.1 18.9 17.4 12.5 16.1 9.6 11.3 12.2 13.7 24.4 8.4 7.5 10.3 11.4 19.7 7.2 6.3 9.2 2.0 18.2 16.0 13.7 17.9 9.9 5.2 12.1 13.7 11.5 9.3 5.9 9.5 10.6 7.4 6.7 DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992241-162074542 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 133.1;parathyroid gland: 75.5" "Cell line enhanced" "Detected in some" "ASC diff: 41.8;ASC TERT1: 42.4;BJ hTERT+: 38.9;RPTEC TERT1: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "MAIT T-cell: 26.7" "Lineage enriched" "Detected in many" 10 "T-cells: 26.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB045970 Enhanced "Secreted in other tissues" 170000000 "CAB045970: AB_11140529" "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavourable (1.98e-4)" "prognostic favourable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favourable (4.99e-4)" "unprognostic (1.21e-2)" 9.5 2.9 0.3 3.2 0.5 0.0 5.0 0.3 1.4 2.2 50.0 0.2 36.9 19.1 2.2 3.5 1.2 1.2 5.2 2.1 0.4 0.3 29.1 12.2 5.4 2.1 0.4 0.2 2.7 1.8 75.5 0.3 24.0 0.2 21.1 2.8 0.6 46.9 38.8 2.4 4.4 133.1 0.9 0.8 5.0 1.2 0.6 0.1 6.2 1.0 1.4 1.1 1.0 2.6 0.1 2.1 0.3 0.0 2.6 26.7 2.5 0.0 0.0 0.1 0.0 41.8 42.4 0.1 7.7 38.9 2.1 7.6 7.8 0.2 0.0 2.9 13.4 0.2 0.1 0.0 1.3 2.4 0.1 0.0 0.0 11.7 17.1 0.0 0.0 4.8 0.0 13.1 0.1 1.2 0.0 0.0 0.7 0.0 0.7 0.1 0.4 16.0 0.0 0.0 0.1 56.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.9 4.5 0.2 0.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 3.2 0.0 26.7 0.1 8.3 5.2 0.6 0.0 8.3 3.3 0.3 2.6 0.0 2.1 0.9 2.5 0.3 0.5 0.3 1.4 0.4 0.3 0.4 0.2 0.2 0.1 DPP6 "DPL1, DPPX" ENSG00000130226 "Dipeptidyl peptidase like 6" P42658 7 153887097-154894285 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease mutation, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.7;endometrium 1: 24.5;thyroid gland: 24.1" "Cell line enriched" "Detected in some" 9 "NTERA-2: 11.0" "Cancer enriched" "Detected in some" 11 "glioma: 12.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050509 Enhanced Supported "HPA050509: " "unprognostic (1.29e-1)" "unprognostic (3.55e-2)" "unprognostic (5.68e-2)" "unprognostic (5.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.28e-1)" "unprognostic (2.73e-1)" "unprognostic (5.83e-4)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.04e-3)" "unprognostic (2.94e-3)" "unprognostic (1.85e-4)" "unprognostic (1.05e-1)" "unprognostic (4.61e-3)" "unprognostic (6.11e-2)" 1.6 7.2 15.4 1.4 32.5 1.3 1.5 26.6 45.7 2.3 6.8 8.7 0.0 1.6 24.5 3.1 1.5 4.6 1.3 1.4 26.6 15.2 3.6 1.2 2.2 1.3 14.0 22.7 1.3 4.0 1.2 4.9 1.3 18.8 1.5 2.4 0.4 1.3 8.1 4.6 3.7 2.0 15.8 7.2 4.2 3.5 7.9 10.0 0.0 24.1 0.0 1.2 1.3 0.4 0.6 0.6 1.9 0.9 0.9 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 11.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.9 0.4 0.7 0.4 0.6 0.7 0.6 0.6 0.4 0.4 0.6 0.7 0.7 1.6 0.9 0.9 0.6 0.5 0.3 15.4 32.5 26.6 32.4 26.6 15.2 14.0 22.7 18.8 10.0 DPP7 "DPP2, DPPII" ENSG00000176978 "Dipeptidyl peptidase 7" Q9UHL4 9 137110542-137115177 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 56.7;THP-1: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021282, CAB025541, HPA059381" Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" 1300000 "Golgi apparatus, Vesicles" "CAB025541: , HPA021282: AB_1847673, HPA059381: " "unprognostic (1.15e-1)" "unprognostic (5.54e-2)" "prognostic unfavourable (6.07e-6)" "unprognostic (6.78e-3)" "unprognostic (1.25e-1)" "unprognostic (8.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.10e-2)" "unprognostic (2.28e-2)" "unprognostic (5.71e-3)" "prognostic favourable (8.31e-5)" "unprognostic (7.99e-2)" "unprognostic (1.46e-2)" "unprognostic (2.56e-2)" "unprognostic (1.72e-1)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" 28.1 45.2 23.7 23.4 35.3 31.8 20.8 23.5 27.5 21.5 22.0 24.9 40.7 23.2 17.5 35.8 19.1 27.0 30.2 44.7 24.6 29.2 21.0 29.9 25.6 34.8 29.7 25.9 14.3 55.4 23.3 42.5 21.9 24.2 28.8 6.9 32.8 73.1 41.6 25.3 26.9 17.8 22.8 21.7 29.1 24.4 30.9 26.8 18.9 41.2 17.5 24.7 21.3 16.6 20.0 60.8 12.2 43.1 19.2 36.8 38.2 6.8 10.9 0.9 0.9 13.5 10.8 1.4 10.4 17.0 6.9 4.5 10.3 5.7 13.6 11.4 6.8 14.9 8.0 2.0 0.3 13.3 0.5 6.2 15.0 0.3 30.2 16.8 34.9 13.3 8.3 3.0 6.2 9.0 13.6 10.6 4.6 19.0 8.4 16.0 3.7 10.7 12.4 0.1 56.7 11.0 7.7 17.4 12.1 12.0 31.6 29.4 11.3 54.5 10.9 17.7 6.0 11.2 7.2 13.0 7.4 3.6 21.2 10.2 7.9 6.8 43.1 12.2 34.4 37.6 35.5 19.7 31.1 29.6 41.7 20.0 28.1 25.1 2.6 19.2 22.6 60.8 36.8 38.2 23.7 35.3 23.5 27.5 24.6 29.2 29.7 25.9 24.2 26.8 DPP8 "DP8, DPRP1, FLJ14920, FLJ20283, MGC26191, MSTP141" ENSG00000074603 "Dipeptidyl peptidase 8" Q6V1X1 15 65442463-65517704 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008706 Approved Supported Cytosol Cytosol "HPA008706: AB_1078665" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.60e-2)" "unprognostic (2.98e-1)" "unprognostic (2.46e-1)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (4.09e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-2)" "unprognostic (1.01e-1)" "unprognostic (7.58e-2)" "unprognostic (8.56e-2)" "unprognostic (2.59e-1)" 15.6 16.1 16.4 14.9 18.8 16.2 13.9 22.9 24.9 15.5 14.5 15.0 12.7 18.0 15.9 13.9 13.1 11.1 12.4 18.8 15.1 14.6 16.0 9.9 13.3 16.0 15.4 11.8 16.2 11.7 22.2 14.5 15.9 21.7 13.5 15.8 13.9 15.6 20.8 30.5 14.2 16.5 16.2 17.5 17.2 13.2 29.9 15.8 22.5 17.4 12.5 16.0 16.2 13.2 10.7 8.1 20.0 10.8 6.1 10.3 5.3 9.4 15.3 10.1 10.1 11.4 16.4 8.6 15.3 18.1 13.7 13.2 6.6 8.2 16.7 12.1 19.1 17.7 19.5 11.0 16.8 14.1 12.1 16.1 11.8 6.3 11.9 20.7 15.9 12.2 10.5 11.1 10.5 15.0 10.9 15.6 16.8 7.6 11.0 7.6 6.9 7.9 14.7 18.7 16.2 11.3 20.6 7.2 12.7 9.9 10.1 15.4 9.3 12.4 18.9 18.4 12.9 8.7 16.3 20.2 26.4 17.0 13.9 20.9 13.2 20.0 9.1 11.1 9.9 9.2 10.3 9.2 8.6 9.5 8.1 10.7 8.6 9.2 18.3 6.1 10.8 7.5 8.9 5.3 16.4 18.8 22.9 24.4 15.1 14.6 15.4 11.8 21.7 15.8 DPP9 ENSG00000142002 "Dipeptidyl peptidase 9" Q86TI2 19 4675224-4724673 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036059 Approved Supported Cytosol Cytosol "HPA036059: AB_10671240" "prognostic favourable (4.96e-4)" "unprognostic (4.16e-2)" "unprognostic (2.03e-1)" "prognostic favourable (6.21e-5)" "unprognostic (5.67e-2)" "unprognostic (8.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (8.85e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-1)" "unprognostic (3.39e-2)" "prognostic unfavourable (3.38e-8)" "prognostic favourable (7.72e-5)" "unprognostic (1.55e-1)" "unprognostic (4.22e-1)" "unprognostic (1.80e-1)" 18.1 11.9 11.7 24.3 14.0 25.8 13.7 13.0 12.5 12.6 16.3 14.2 15.8 18.3 15.3 10.5 17.4 11.6 13.5 19.7 11.0 7.2 13.5 38.6 19.3 20.7 14.7 7.1 13.5 15.5 9.5 9.8 15.2 11.7 14.0 13.1 14.2 13.1 12.9 46.4 21.5 18.9 14.2 9.3 21.0 14.7 7.1 13.9 24.3 14.6 16.3 17.0 16.0 21.7 10.3 9.0 10.0 10.5 13.4 13.8 8.0 23.5 18.8 5.5 8.7 8.5 11.9 10.1 13.8 18.4 23.3 15.2 16.9 18.3 11.2 10.5 17.8 16.1 11.3 63.6 14.3 14.3 10.9 8.1 10.3 14.4 13.0 14.2 17.8 9.1 14.8 36.4 21.6 21.0 11.2 24.9 20.1 6.4 16.5 9.2 11.4 28.0 10.3 11.9 13.0 12.1 16.2 7.9 7.1 11.9 21.6 9.1 5.9 11.9 16.9 20.9 9.1 32.3 27.5 17.4 18.1 11.2 20.4 16.5 17.5 10.0 8.8 9.4 13.8 10.5 10.5 10.3 6.4 11.2 9.0 6.8 6.3 9.9 4.7 13.4 7.8 4.3 11.3 8.0 11.7 14.0 13.0 12.5 11.0 7.2 14.7 7.1 11.7 13.9 DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain 1300000 "CAB033241: AB_2094323, HPA045210: " "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavourable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" 24.9 15.4 8.8 17.0 20.9 7.4 18.4 2.0 11.2 17.9 15.6 20.3 6.4 17.0 13.7 10.8 19.0 13.5 20.5 13.3 8.3 6.1 10.5 52.2 26.0 25.7 25.3 7.1 20.4 9.7 15.5 18.4 8.0 13.9 11.6 8.4 6.2 16.7 11.6 6.7 7.7 22.4 15.5 15.0 27.7 12.0 6.0 22.2 27.4 13.5 10.0 10.4 16.3 19.6 2.6 14.3 28.3 28.1 5.7 7.3 8.0 7.8 2.2 2.9 0.0 16.0 27.6 0.0 12.8 11.6 11.9 8.8 0.0 3.3 4.1 18.8 11.8 1.9 0.0 3.0 21.9 4.1 2.6 3.5 4.2 0.0 7.1 1.5 0.2 21.7 1.1 9.5 10.9 9.7 0.1 13.3 6.2 0.0 8.2 2.2 0.3 2.7 0.0 13.7 6.5 14.6 0.0 4.1 3.2 10.9 0.9 0.1 0.0 3.6 11.1 25.9 1.8 20.8 25.1 1.1 0.0 0.0 3.8 4.5 20.4 6.3 28.1 1.7 5.5 13.0 7.3 0.9 6.5 5.3 14.3 2.6 6.2 5.4 28.3 5.7 10.7 0.4 7.0 8.0 8.8 20.9 2.0 11.2 8.3 6.1 25.3 7.1 13.9 22.2 DPYS DHPase ENSG00000147647 Dihydropyrimidinase Q14117 8 104330324-104467053 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "kidney: 42.2;liver: 103.6" "Cell line enhanced" "Detected in some" "HDLM-2: 2.7;HSkMC: 2.4;U-266/84: 2.0" "Group enriched" "Detected in some" 21 "liver cancer: 57.6;renal cancer: 11.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "intermediate monocyte: 1.2" "Lineage enriched" "Detected in single" 13 "monocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA024785 Enhanced 89000 "HPA024785: AB_1847856" "unprognostic (1.54e-3)" "unprognostic (2.33e-1)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-1)" "unprognostic (2.38e-3)" "unprognostic (4.16e-4)" "unprognostic (1.56e-1)" "unprognostic (3.53e-2)" "unprognostic (3.85e-3)" "unprognostic (2.43e-1)" "unprognostic (4.81e-2)" "unprognostic (9.56e-3)" "unprognostic (2.72e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-1)" 2.5 0.6 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.2 2.1 0.1 0.0 0.0 0.0 1.6 0.1 0.2 1.3 0.0 0.0 0.1 42.2 103.6 0.2 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.1 0.1 0.9 0.0 0.2 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.7 0.0 0.0 1.2 0.0 0.0 2.7 0.0 0.1 0.0 0.2 0.0 1.3 1.1 2.4 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 1.4 0.0 0.7 0.1 0.6 1.3 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.0 1.5 0.0 0.7 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 DQX1 FLJ23757 ENSG00000144045 "DEAQ-box RNA dependent ATPase 1" Q8TE96 2 74518131-74526336 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 41.0" "Group enriched" "Detected in some" 4 "HBEC3-KT: 6.4;Hep G2: 18.0;hTCEpi: 6.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039158 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA039158: AB_10960125" "unprognostic (2.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (9.95e-2)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-1)" "unprognostic (4.54e-2)" "unprognostic (1.68e-1)" "unprognostic (7.67e-2)" "unprognostic (2.21e-2)" "unprognostic (0.00e+0)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-3)" 0.1 0.0 0.1 2.1 0.2 0.0 0.1 0.1 0.1 0.8 13.3 0.2 0.1 14.7 0.1 0.1 3.7 0.2 3.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 1.0 0.1 0.2 5.1 0.1 0.6 0.1 0.1 1.5 41.0 0.3 0.1 0.2 2.9 0.1 0.1 0.2 0.1 0.7 1.5 1.1 1.4 0.7 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.5 0.1 0.3 0.0 0.0 0.7 0.1 6.4 0.1 0.0 0.3 0.4 0.1 18.0 0.0 0.2 0.3 0.0 6.6 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.0 1.2 0.0 0.1 0.0 2.5 0.0 0.6 0.0 0.0 0.8 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 DSE "DS-Epi1, DSEPI, SART2" ENSG00000111817 "Dermatan sulfate epimerase" Q9UL01 6 116254173-116444860 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease mutation, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 8.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014764, HPA052151" Uncertain Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" Nucleoplasm Cytosol "HPA014764: AB_1856587, HPA052151: " "unprognostic (1.28e-1)" "prognostic unfavourable (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (3.23e-3)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.02e-2)" "unprognostic (7.81e-2)" "prognostic unfavourable (6.34e-4)" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "prognostic unfavourable (1.50e-4)" "unprognostic (6.19e-3)" "unprognostic (2.54e-2)" "unprognostic (2.06e-1)" "unprognostic (1.10e-2)" 32.3 10.6 7.4 22.3 10.7 13.1 34.8 5.4 7.7 16.0 12.8 4.9 9.9 5.3 11.7 18.5 13.5 15.3 12.9 16.1 8.1 4.3 11.2 10.4 17.7 13.1 9.8 4.5 21.0 4.0 15.4 20.9 21.7 13.1 13.0 7.1 14.3 9.3 9.4 8.5 16.9 10.7 12.8 16.1 24.9 7.6 10.9 9.0 8.3 8.7 10.9 8.3 14.6 29.4 3.6 8.9 2.5 3.9 0.2 1.1 1.2 10.4 2.2 7.8 7.3 21.1 14.0 8.8 12.3 29.0 15.5 22.7 0.0 2.9 0.2 1.1 21.4 19.9 1.1 28.9 20.3 10.7 4.8 0.7 3.3 0.1 23.6 0.4 0.5 29.6 12.5 17.1 16.8 9.1 0.2 4.8 7.3 0.3 1.3 0.6 4.2 0.6 1.8 7.2 4.9 10.2 0.7 2.6 2.0 11.9 0.0 0.2 0.1 1.2 3.4 15.6 4.6 3.9 9.8 1.0 0.3 0.5 8.3 1.3 1.8 0.7 3.1 0.1 1.0 3.9 0.6 3.2 0.9 0.4 8.9 3.6 1.1 0.4 2.5 0.2 2.2 4.2 0.2 1.2 7.4 10.7 5.4 7.7 8.1 4.3 9.8 4.5 13.1 9.0 DSTYK "DustyPK, KIAA0472, RIP5, RIPK5" ENSG00000133059 "Dual serine/threonine and tyrosine protein kinase" Q6XUX3 1 205142505-205211566 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044140 Uncertain Uncertain "Nuclear speckles,Intermediate filaments" "Nuclear speckles, Intermediate filaments" "HPA044140: AB_10965031" "unprognostic (1.42e-2)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.43e-2)" "unprognostic (9.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (3.26e-2)" "unprognostic (7.80e-2)" "unprognostic (1.93e-1)" "unprognostic (1.55e-1)" "prognostic unfavourable (8.73e-5)" 6.4 9.2 13.8 4.4 13.3 19.6 8.2 20.4 16.4 8.4 6.5 6.8 4.2 3.3 10.5 7.4 6.7 9.2 5.4 5.7 10.7 9.0 9.3 2.5 7.3 5.4 8.1 11.8 14.0 5.9 22.0 11.0 7.1 12.2 7.2 4.6 9.2 6.2 8.8 14.6 14.0 4.8 8.8 11.0 7.0 5.3 11.5 9.2 7.1 8.4 3.6 5.3 7.6 6.4 3.5 3.1 9.8 3.5 4.8 5.1 1.6 6.8 4.5 4.8 5.8 7.0 11.9 3.4 8.6 8.6 9.0 6.2 2.0 3.8 5.1 2.6 14.5 4.9 5.2 5.5 9.2 2.4 5.7 9.2 5.9 2.1 6.3 2.6 4.9 7.0 8.4 9.2 8.8 6.6 11.9 3.4 7.1 4.7 2.0 2.3 5.2 5.4 1.8 8.7 4.4 6.0 4.3 2.7 5.2 7.3 7.6 24.1 5.6 3.4 6.5 5.6 5.7 8.5 5.7 3.5 2.5 3.0 6.6 3.6 20.1 9.8 3.5 6.0 4.6 2.5 4.3 2.7 3.4 3.8 3.1 3.5 5.1 3.7 5.1 4.8 1.8 2.3 2.0 1.6 13.8 13.3 20.4 16.4 10.7 9.0 8.1 11.8 12.2 9.2 DTD1 "bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, MGC119131, MGC41905, pqn-68" ENSG00000125821 "D-tyrosyl-tRNA deacylase 1" Q8TEA8 20 18587893-18766644 "Enzymes, Predicted intracellular proteins" "DNA replication" "DNA-binding, Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA040981 Uncertain Uncertain Nucleoli,Cytosol 180000 "Nucleoli, Cytosol" "HPA040981: AB_10673268" "unprognostic (3.32e-1)" "unprognostic (1.05e-1)" "unprognostic (1.82e-1)" "unprognostic (5.94e-2)" "unprognostic (1.83e-1)" "unprognostic (2.90e-1)" "unprognostic (1.27e-3)" "unprognostic (9.67e-2)" "unprognostic (1.72e-1)" "unprognostic (1.81e-1)" "unprognostic (6.84e-2)" "unprognostic (1.32e-1)" "unprognostic (9.09e-3)" "unprognostic (2.42e-1)" "unprognostic (8.44e-2)" "unprognostic (2.59e-2)" "unprognostic (8.53e-2)" 14.9 17.7 25.2 13.6 26.5 13.6 19.7 22.4 35.4 13.5 13.7 22.2 10.5 10.6 14.4 17.2 18.8 14.5 11.1 16.7 24.7 29.5 20.1 9.4 13.7 15.5 25.2 30.4 19.1 19.7 20.3 23.7 12.7 27.3 13.6 16.0 17.1 17.6 12.4 22.5 17.6 9.8 15.0 30.9 12.7 16.3 20.6 14.4 4.8 29.5 24.9 17.4 13.4 12.6 20.9 27.5 29.9 20.6 16.4 22.5 12.6 18.5 20.9 20.6 20.2 8.8 16.4 11.5 16.4 15.2 13.1 14.4 13.6 14.5 0.0 11.2 15.3 10.5 16.4 34.8 13.8 9.0 11.8 20.7 4.8 22.7 27.9 16.0 11.2 13.0 28.0 14.7 54.4 22.2 12.9 24.1 19.0 27.2 3.4 29.2 19.1 46.0 0.0 30.7 15.6 19.9 10.0 28.2 21.3 8.8 24.4 42.4 13.9 10.0 21.8 17.3 9.4 22.1 22.2 19.4 19.2 10.3 11.9 18.8 14.3 29.9 14.5 10.4 22.2 20.6 22.2 20.9 21.7 22.5 27.5 17.8 16.0 16.7 17.1 16.4 20.5 6.4 16.1 12.6 25.2 26.5 22.4 35.4 24.7 29.5 25.2 30.4 27.3 14.4 DTD2 "C14orf126, MGC9912" ENSG00000129480 "D-tyrosyl-tRNA deacylase 2 (putative)" Q96FN9 14 31446036-31457510 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA001117 Approved Approved Vesicles Vesicles "HPA001117: " "unprognostic (2.56e-3)" "unprognostic (9.38e-2)" "unprognostic (1.27e-3)" "unprognostic (3.24e-2)" "unprognostic (8.45e-2)" "prognostic unfavourable (9.33e-4)" "unprognostic (3.04e-2)" "unprognostic (1.64e-1)" "unprognostic (8.74e-3)" "unprognostic (2.91e-1)" "unprognostic (5.28e-2)" "unprognostic (6.96e-2)" "unprognostic (1.24e-1)" "unprognostic (2.32e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "prognostic unfavourable (5.74e-6)" 11.9 11.0 12.4 6.8 16.0 2.9 13.1 9.1 19.6 6.7 6.8 15.2 3.8 5.6 8.0 7.7 9.9 7.5 6.9 6.0 13.2 11.0 8.6 11.6 10.0 8.0 13.6 8.9 8.6 9.9 8.3 9.6 6.2 13.3 8.8 8.2 7.1 10.3 6.1 2.3 8.2 5.3 8.3 10.9 6.7 5.7 14.6 9.9 12.3 9.4 2.8 7.8 7.5 6.5 6.4 6.6 3.5 4.8 6.9 9.1 4.8 8.4 7.1 6.2 8.1 11.6 9.8 4.3 7.8 7.6 6.2 5.5 3.8 8.1 16.1 5.3 8.8 8.2 9.9 8.7 10.6 8.7 4.4 4.6 5.2 21.5 12.5 9.2 5.7 11.0 10.0 5.4 12.4 9.0 8.9 7.7 8.2 10.2 13.3 8.3 8.4 7.4 9.1 4.6 8.4 11.5 7.4 9.4 6.2 12.7 16.6 8.9 15.2 4.9 6.5 6.8 6.0 5.4 6.7 9.6 17.8 15.7 3.0 8.5 10.9 3.5 4.8 1.7 4.0 4.1 5.6 4.9 5.9 4.3 6.6 6.4 9.1 6.0 3.0 6.9 2.0 4.0 2.9 4.8 12.4 16.0 9.1 19.6 13.2 11.0 13.6 8.9 13.3 9.9 DTX1 "hDx-1, RNF140" ENSG00000135144 "Deltex E3 ubiquitin ligase 1" Q86Y01 12 113056709-113098028 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.7;lymphoid tissue: 13.3" "Group enriched" "Detected in some" 12 "Daudi: 40.0;REH: 16.4;U-698: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "naive B-cell: 2.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051249, HPA055275" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA051249: , HPA055275: " "unprognostic (2.13e-3)" "unprognostic (3.20e-3)" "unprognostic (4.24e-4)" "unprognostic (2.01e-1)" "unprognostic (7.48e-3)" "unprognostic (1.59e-3)" "unprognostic (2.49e-3)" "unprognostic (1.81e-1)" "unprognostic (9.55e-2)" "unprognostic (6.87e-2)" "unprognostic (2.19e-1)" "unprognostic (1.58e-1)" "prognostic unfavourable (3.02e-5)" "unprognostic (2.41e-2)" "unprognostic (4.70e-1)" "unprognostic (1.63e-1)" "unprognostic (4.78e-3)" 9.7 2.3 6.1 8.9 7.0 3.2 3.9 7.3 8.3 0.8 0.7 1.1 0.5 1.6 2.0 0.5 1.2 1.7 1.0 2.7 5.4 5.9 1.7 6.4 0.5 13.3 3.7 4.2 0.5 2.0 0.0 2.2 0.9 4.6 0.8 0.2 1.4 3.2 0.5 0.5 0.5 2.2 0.5 1.1 9.8 1.0 4.9 0.5 0.5 1.3 0.5 8.1 0.5 0.5 2.3 0.0 0.0 0.0 1.0 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.6 0.0 0.7 0.0 16.4 0.0 0.9 0.0 0.0 1.0 2.7 0.1 0.1 0.9 0.0 0.1 0.4 0.0 1.5 0.0 0.0 0.2 0.0 40.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.5 0.0 0.0 2.3 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.2 6.1 7.0 7.3 7.1 5.4 5.9 3.7 4.2 4.6 0.5 DTX2 "KIAA1528, RNF58" ENSG00000091073 "Deltex E3 ubiquitin ligase 2" Q86UW9 7 76461676-76505995 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 19.1;esophagus: 19.2" "Cell line enhanced" "Detected in all" "A549: 28.0;CAPAN-2: 46.2" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042931 Approved Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA042931: " "unprognostic (1.72e-1)" "unprognostic (1.73e-1)" "unprognostic (1.62e-2)" "unprognostic (1.58e-2)" "prognostic unfavourable (8.47e-4)" "unprognostic (2.85e-2)" "unprognostic (1.28e-3)" "unprognostic (7.54e-2)" "unprognostic (4.76e-2)" "unprognostic (2.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-2)" "prognostic unfavourable (1.13e-8)" "unprognostic (2.87e-2)" "unprognostic (1.53e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-2)" 2.9 1.3 0.4 4.8 0.5 1.5 3.2 0.4 0.2 4.8 5.7 4.1 3.0 0.0 19.2 3.2 3.8 1.8 0.5 0.5 1.6 2.8 3.2 3.9 0.7 2.7 4.3 3.8 2.1 1.8 4.6 3.2 10.5 1.3 2.8 11.6 5.5 1.3 1.1 4.9 6.1 8.3 2.7 4.0 4.6 8.8 7.0 14.7 19.1 14.1 3.3 9.0 6.4 12.7 28.0 4.2 6.1 2.4 2.3 9.0 2.7 2.4 3.1 4.2 7.8 46.2 4.0 2.0 2.7 9.6 2.2 13.3 1.9 8.9 4.7 2.3 5.7 6.8 3.2 3.3 5.8 4.1 8.1 7.9 4.3 2.3 6.9 6.0 3.7 6.2 5.0 11.5 6.0 4.2 5.6 3.8 7.1 1.4 10.0 1.6 3.4 4.5 7.7 3.7 7.7 8.8 2.4 17.3 8.2 5.8 11.0 4.5 5.3 4.5 3.7 3.5 8.8 12.4 9.2 13.3 7.6 10.9 5.5 6.0 6.4 7.5 8.4 7.0 6.6 6.9 19.1 3.3 14.1 14.7 9.0 6.4 DTX3 "FLJ34766, RNF154" ENSG00000178498 "Deltex E3 ubiquitin ligase 3" Q8N9I9 12 57604622-57609804 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in all" "glioma: 54.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 2.0;T-cells: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059654 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA059654: " "unprognostic (2.31e-2)" "unprognostic (8.80e-2)" "unprognostic (2.06e-2)" "unprognostic (3.68e-1)" "unprognostic (3.35e-1)" "unprognostic (2.58e-2)" "unprognostic (6.91e-2)" "prognostic favourable (9.87e-4)" "unprognostic (1.84e-1)" "unprognostic (4.26e-2)" "prognostic favourable (1.44e-4)" "unprognostic (8.62e-2)" "unprognostic (5.44e-3)" "unprognostic (7.99e-2)" "unprognostic (8.81e-2)" "unprognostic (9.51e-2)" "unprognostic (3.48e-2)" 7.2 18.8 22.7 9.0 35.2 3.5 9.4 47.8 53.6 17.6 22.8 23.7 11.0 6.7 29.7 30.6 9.7 31.8 14.1 20.5 23.8 19.8 11.4 2.4 12.2 11.0 18.3 28.4 36.3 12.0 23.9 32.7 16.0 22.5 21.1 10.1 20.4 13.2 29.5 10.9 7.9 9.4 28.7 16.9 11.2 11.2 7.8 21.6 6.8 16.8 5.1 8.8 11.8 13.5 0.3 0.6 0.0 0.0 2.0 5.5 1.8 3.1 8.4 25.0 0.0 0.0 0.0 0.1 5.1 13.3 11.3 11.5 4.3 13.6 4.5 7.9 11.1 5.2 0.0 0.6 8.0 11.3 1.5 2.6 13.0 4.5 19.3 0.0 0.0 9.5 6.3 8.6 0.1 12.6 0.0 15.4 8.6 7.0 13.7 0.1 19.7 0.7 0.0 20.9 0.2 1.0 8.4 18.2 28.8 4.0 1.2 2.4 14.4 6.9 0.0 14.8 5.9 6.8 7.3 25.2 18.9 0.0 9.5 0.0 7.7 0.0 0.0 0.0 5.5 0.0 1.3 0.3 2.1 2.5 0.2 0.3 1.9 3.5 0.0 2.0 0.0 0.6 4.2 1.8 22.7 35.2 47.8 53.6 23.8 19.8 18.3 28.4 22.5 21.6 DTX3L "BBAP, RNF143" ENSG00000163840 "Deltex E3 ubiquitin ligase 3L" Q8TDB6 3 122564238-122575203 "Enzymes, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Protein transport, Transport, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 35.3;BJ hTERT+ SV40 Large T+ RasG12V: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010570 Uncertain Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA010570: AB_1847877" "unprognostic (8.15e-2)" "unprognostic (7.36e-3)" "unprognostic (5.04e-2)" "unprognostic (3.74e-3)" "unprognostic (9.51e-2)" "unprognostic (9.22e-2)" "unprognostic (1.82e-1)" "unprognostic (1.11e-2)" "unprognostic (9.23e-2)" "unprognostic (1.43e-1)" "prognostic unfavourable (8.99e-4)" "unprognostic (2.76e-2)" "unprognostic (2.33e-2)" "unprognostic (7.77e-2)" "unprognostic (9.28e-2)" "unprognostic (3.33e-2)" "unprognostic (2.61e-2)" 32.3 13.0 5.9 22.7 8.4 8.1 11.2 2.0 6.8 14.2 18.5 5.9 6.0 14.8 14.0 12.8 17.9 12.0 15.1 21.5 5.0 5.1 17.3 39.2 21.3 18.3 6.4 3.3 21.7 18.5 10.3 13.9 22.2 6.5 20.9 12.1 7.6 13.9 9.8 14.6 6.2 31.8 10.8 9.7 35.2 12.4 4.9 6.9 24.8 23.9 8.0 18.3 17.0 22.1 6.4 6.5 21.9 13.6 7.8 10.2 6.7 11.4 3.5 1.0 3.0 4.7 10.9 3.9 3.0 11.1 35.3 43.7 3.4 11.8 1.3 5.9 4.9 11.6 3.5 4.8 7.8 9.7 1.3 10.0 2.6 3.6 9.3 5.1 7.9 9.4 5.7 5.3 3.0 6.6 1.2 7.2 2.6 3.5 12.4 3.6 0.6 6.5 13.8 8.1 2.2 9.0 7.4 1.5 1.6 6.2 2.8 22.3 3.2 6.5 8.1 4.0 5.7 0.4 3.8 2.6 1.4 6.1 7.0 6.7 4.1 12.5 8.5 8.7 9.3 13.6 10.2 5.9 7.8 10.0 6.5 6.4 7.1 7.6 21.9 7.8 13.5 0.7 7.4 6.7 5.9 8.4 2.0 6.8 5.0 5.1 6.4 3.3 6.5 6.9 DTX4 "KIAA0937, RNF155" ENSG00000110042 "Deltex E3 ubiquitin ligase 4" Q9Y2E6 11 59171430-59208587 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 42.8" "Cell line enhanced" "Detected in many" "AF22: 13.3;BEWO: 27.0;CACO-2: 14.6;CAPAN-2: 15.5;RT4: 40.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 63.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 6.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056760, HPA059294" Approved Approved Vesicles Vesicles "HPA056760: , HPA059294: " "unprognostic (3.23e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (4.97e-2)" "unprognostic (5.03e-1)" "unprognostic (2.92e-1)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (3.04e-1)" "prognostic unfavourable (8.94e-4)" "unprognostic (5.51e-2)" "unprognostic (2.51e-1)" "prognostic favourable (5.81e-4)" "unprognostic (2.57e-3)" 7.0 2.2 8.9 7.6 12.8 8.2 7.9 14.0 16.5 8.9 17.7 29.8 1.4 16.7 4.3 2.3 3.7 6.5 9.5 2.1 10.7 10.9 6.5 23.9 17.7 5.2 15.3 8.8 16.3 5.9 1.7 3.3 15.3 24.8 5.6 18.4 7.7 16.0 3.7 1.5 4.2 14.3 3.6 42.8 5.0 12.2 1.9 9.1 0.8 12.4 2.3 6.7 19.8 14.7 3.3 6.1 3.1 1.0 0.1 0.1 0.2 2.0 2.3 13.3 0.2 3.8 0.2 27.0 0.2 1.1 0.1 0.1 14.6 15.5 4.8 0.9 0.3 6.9 4.1 5.0 0.0 0.3 0.2 0.0 2.6 4.7 1.0 0.4 0.9 0.6 8.4 0.0 0.2 0.0 0.0 0.5 0.6 1.1 0.2 0.0 6.8 0.6 1.6 11.7 0.5 1.1 40.5 0.0 0.0 10.3 2.7 0.3 2.0 0.2 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.5 0.1 1.2 1.0 1.5 1.0 0.7 0.1 1.0 0.0 2.2 0.1 0.0 1.4 3.3 0.0 0.0 3.1 0.1 0.5 6.1 0.0 0.2 8.9 12.8 14.0 16.5 10.7 10.9 15.3 8.8 24.8 9.1 DTYMK "CDC8, TMPK, TYMK" ENSG00000168393 "Deoxythymidylate kinase" P23919 2 241675742-241686991 "Enzymes, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042593, HPA042719" Approved Approved Mitochondria Mitochondria "HPA042593: AB_10959590, HPA042719: AB_10960633" "unprognostic (1.90e-1)" "unprognostic (6.95e-2)" "unprognostic (4.14e-1)" "unprognostic (8.61e-2)" "unprognostic (1.89e-1)" "unprognostic (9.45e-2)" "prognostic unfavourable (1.73e-5)" "unprognostic (1.44e-2)" "unprognostic (2.64e-2)" "unprognostic (5.50e-2)" "unprognostic (2.60e-2)" "unprognostic (6.94e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (7.13e-2)" "unprognostic (6.81e-2)" "unprognostic (5.07e-2)" "unprognostic (9.19e-2)" 12.4 17.6 11.6 17.3 15.0 29.1 14.4 14.5 12.4 10.0 13.8 16.5 9.3 12.0 12.4 9.7 20.0 9.7 10.2 9.4 9.0 6.5 15.5 19.5 10.5 21.0 14.0 9.5 9.5 13.6 5.0 8.8 10.4 11.8 11.5 11.7 10.8 9.6 10.0 6.7 17.9 13.0 13.0 9.5 18.8 13.5 11.1 15.1 20.7 9.4 16.1 17.9 11.7 11.9 19.8 21.1 12.0 24.7 15.7 21.8 15.7 25.2 27.9 24.2 30.8 8.0 8.7 25.7 20.7 15.6 27.5 32.5 12.7 30.6 12.2 6.4 16.7 21.3 22.3 25.1 14.8 28.8 26.5 26.2 23.4 24.1 6.6 16.6 21.7 6.1 6.8 26.6 10.8 26.4 29.4 10.3 29.2 26.3 30.6 28.8 23.9 23.5 26.2 35.7 17.0 15.9 14.6 29.3 18.3 13.4 20.7 16.5 18.8 29.7 17.1 40.2 28.9 25.6 38.1 11.6 12.2 34.3 32.2 26.6 46.7 12.0 14.9 9.5 17.4 24.7 16.8 19.2 16.1 18.2 10.5 19.8 16.0 14.7 2.5 15.7 18.8 21.1 21.8 15.7 11.6 15.0 14.5 12.4 9.0 6.5 14.0 9.5 11.8 15.1 DUOX1 "LNOX1, NOXEF1, THOX1" ENSG00000137857 "Dual oxidase 1" Q9NRD9 15 45129933-45165576 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 48.7" "Group enriched" "Detected in some" 5 "HaCaT: 33.8;hTCEpi: 16.4;RT4: 18.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.4" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "cerebellum: 17.5" HPA023544 Approved "HPA023544: AB_1847878" "unprognostic (2.85e-2)" "prognostic favourable (4.31e-6)" "unprognostic (2.49e-2)" "unprognostic (8.84e-3)" "unprognostic (1.44e-2)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (2.57e-2)" "unprognostic (5.87e-2)" "unprognostic (6.02e-3)" "unprognostic (5.13e-2)" "unprognostic (1.19e-1)" "unprognostic (8.91e-3)" "unprognostic (2.23e-1)" "unprognostic (3.06e-2)" "unprognostic (1.14e-2)" "unprognostic (3.03e-1)" 0.4 5.2 0.5 0.4 0.8 0.0 2.0 1.2 0.9 18.9 0.6 2.4 43.3 0.1 2.2 37.8 38.3 6.0 6.2 1.1 0.6 0.1 0.2 0.1 48.7 0.1 1.0 0.5 1.2 0.1 1.8 0.9 2.5 0.9 4.8 0.0 4.3 9.8 19.2 0.8 34.2 0.3 1.6 0.5 0.1 18.0 1.0 1.1 0.7 31.9 35.9 31.9 6.2 13.1 0.2 1.5 0.5 0.5 0.1 0.4 0.0 4.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 33.8 0.0 3.2 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.0 0.2 0.0 16.4 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 18.9 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.5 0.0 0.1 0.3 0.0 1.1 0.2 0.2 0.0 0.0 0.1 0.1 1.5 0.2 0.0 0.5 0.8 1.2 0.9 0.6 0.1 1.0 0.5 0.9 1.1 DUPD1 DUSP27 ENSG00000188716 "Dual specificity phosphatase and pro isomerase domain containing 1" Q68J44 10 75037836-75058514 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "skeletal muscle: 38.9" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042964 Uncertain "HPA042964: AB_10795764" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (2.34e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 DUSP1 "CL100, HVH1, MKP-1, PTPN10" ENSG00000120129 "Dual specificity phosphatase 1" P28562 5 172768090-172771195 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 43.1;hTCEpi: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 326.0" "Lineage enriched" "Detected in all" 10 "granulocytes: 326.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069577 Approved Nucleoli,Cytosol Nucleoli Cytosol "HPA069577: " "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (9.73e-2)" "unprognostic (8.17e-2)" "unprognostic (4.64e-1)" "unprognostic (1.58e-3)" "unprognostic (4.18e-2)" "unprognostic (6.94e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (2.76e-2)" "prognostic unfavourable (3.11e-5)" "unprognostic (2.69e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-3)" 158.4 78.0 12.4 68.5 14.0 89.7 91.8 17.4 14.9 81.4 37.1 32.4 48.5 9.4 55.4 71.6 82.7 94.8 138.8 49.2 12.5 11.4 29.8 115.4 135.0 43.5 30.6 9.7 69.4 34.4 26.6 40.8 93.7 29.3 67.1 34.2 61.0 38.1 192.8 54.8 116.1 27.6 65.0 29.5 36.1 53.6 45.9 18.7 10.8 90.4 104.1 46.9 69.0 109.7 2.4 11.5 326.0 31.8 4.5 9.8 14.0 2.1 5.4 1.7 2.3 37.5 22.0 2.9 34.9 10.2 23.5 9.5 5.9 2.5 0.7 10.2 24.5 0.9 1.6 8.6 11.0 19.1 4.6 0.4 11.9 2.5 43.1 0.2 0.8 21.0 75.3 10.6 17.3 7.3 1.7 13.7 15.1 2.5 1.1 1.0 1.5 1.6 40.5 3.2 6.3 16.7 1.1 7.4 3.1 9.4 16.1 1.2 1.3 0.4 19.2 16.7 8.3 16.2 2.6 2.8 1.6 0.6 14.8 0.3 0.6 33.3 24.6 69.8 3.9 25.0 9.8 2.4 3.5 4.0 11.5 2.1 1.7 1.9 326.0 4.5 31.8 0.6 2.8 14.0 12.4 14.0 17.4 14.9 12.5 11.4 30.6 9.7 29.3 18.7 DUSP10 "MKP-5, MKP5" ENSG00000143507 "Dual specificity phosphatase 10" Q9Y6W6 1 221701424-221742176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 35.4" "Cell line enhanced" "Detected in many" "HaCaT: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 15.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016758 Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" Nucleoplasm "Golgi apparatus, Cytosol" "HPA016758: AB_1847880" "unprognostic (1.55e-1)" "unprognostic (2.73e-1)" "unprognostic (1.44e-1)" "unprognostic (6.65e-2)" "unprognostic (3.83e-2)" "unprognostic (2.85e-3)" "prognostic favourable (5.42e-4)" "unprognostic (2.89e-1)" "unprognostic (3.89e-2)" "unprognostic (9.68e-2)" "unprognostic (2.38e-2)" "unprognostic (1.05e-1)" "prognostic unfavourable (3.69e-4)" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (8.88e-3)" "unprognostic (1.97e-2)" 7.4 4.7 6.0 7.1 11.2 23.2 8.2 5.9 11.1 5.7 10.8 21.1 0.3 2.1 4.9 2.7 7.0 8.5 7.6 3.8 7.2 4.0 2.8 35.4 8.0 9.0 14.0 5.6 2.8 18.3 1.8 2.5 4.5 8.4 3.6 4.9 8.5 9.5 1.7 21.0 8.0 6.2 9.7 10.1 6.4 4.5 3.9 14.1 5.6 5.3 10.6 8.6 8.5 4.1 0.8 5.4 4.6 4.2 15.1 12.7 1.6 6.0 2.6 0.2 0.1 18.8 9.7 0.2 4.0 10.6 6.7 5.2 0.1 1.6 4.7 1.4 10.4 41.5 0.9 3.9 5.8 12.0 0.5 8.1 1.1 0.7 4.4 3.6 5.5 13.5 2.9 7.2 7.3 0.2 0.8 1.6 6.4 0.1 0.7 2.7 0.6 0.2 0.4 11.5 0.3 2.3 3.7 15.5 1.2 0.5 0.5 17.2 0.9 2.1 1.4 3.4 0.9 5.1 4.9 2.8 2.0 2.5 5.3 1.6 3.6 4.6 4.2 0.2 3.6 3.7 3.3 0.7 2.5 2.5 5.4 0.8 0.8 1.5 0.3 15.1 1.4 0.2 12.7 1.6 6.0 11.2 5.9 11.1 7.2 4.0 14.0 5.6 8.4 14.1 DUSP12 "DUSP1, YVH1" ENSG00000081721 "Dual specificity phosphatase 12" Q9UNI6 1 161749758-161757238 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008840 Uncertain Supported Nucleoplasm Nucleoplasm "HPA008840: AB_1847884" "unprognostic (3.51e-2)" "unprognostic (2.62e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (2.11e-1)" "unprognostic (4.04e-2)" "prognostic unfavourable (1.99e-5)" "unprognostic (1.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.25e-3)" "unprognostic (9.52e-2)" "unprognostic (2.42e-3)" "prognostic unfavourable (1.55e-7)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-1)" 15.6 12.1 15.0 16.0 17.2 37.8 21.2 27.2 20.3 14.0 14.2 13.9 16.6 11.7 19.5 14.0 12.7 15.6 12.1 11.9 12.6 12.7 14.0 11.4 14.1 18.5 18.6 13.1 18.4 16.7 10.7 18.7 16.4 14.7 13.6 16.0 15.2 13.8 15.1 8.6 12.6 14.4 16.5 12.0 17.4 13.8 8.2 19.4 11.1 15.9 9.4 18.4 14.4 14.1 16.0 17.8 18.7 15.4 23.1 19.4 10.6 18.0 17.0 18.6 12.5 9.9 10.8 17.6 14.4 18.8 22.2 17.2 24.1 15.8 10.9 15.0 17.5 13.0 14.4 17.7 21.7 14.2 12.8 9.8 15.5 15.6 21.1 20.8 9.8 14.6 19.4 19.3 34.8 15.4 17.3 12.0 15.9 16.8 12.1 23.6 29.7 24.7 17.9 18.2 17.9 12.5 22.2 11.9 25.3 12.2 20.5 23.8 17.8 24.0 10.7 19.2 17.9 14.9 30.6 20.3 16.8 26.1 11.9 21.1 18.9 18.7 13.9 10.2 16.1 15.4 19.4 15.5 18.1 15.3 17.8 16.0 17.5 19.1 5.5 23.1 9.2 8.2 15.3 10.6 15.0 17.2 27.2 20.3 12.6 12.7 18.6 13.1 14.7 19.4 DUSP14 "MKP-L, MKP6" ENSG00000276023 "Dual specificity phosphatase 14" O95147 17 37489831-37513501 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 10.7;BJ hTERT+ SV40 Large T+ RasG12V: 12.5;HBF TERT88: 17.9;WM-115: 10.3" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019911 Approved Approved Nucleoplasm,Cytosol 44000 "Nucleoplasm, Cytosol" "HPA019911: AB_1847888" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.60e-1)" "unprognostic (3.22e-2)" "unprognostic (3.43e-3)" "unprognostic (2.02e-3)" "unprognostic (2.18e-1)" "unprognostic (2.59e-1)" "unprognostic (7.02e-3)" "unprognostic (3.81e-1)" "prognostic unfavourable (6.97e-9)" "unprognostic (7.93e-2)" "unprognostic (1.97e-1)" "unprognostic (1.73e-1)" "unprognostic (1.41e-3)" 4.7 3.7 3.3 2.1 6.6 1.1 3.9 1.8 8.0 3.3 1.0 1.5 0.1 0.7 2.7 1.2 7.2 11.7 5.1 2.6 2.3 2.1 6.5 2.4 1.0 1.9 2.5 3.0 2.9 1.7 3.3 11.6 2.6 1.4 1.4 1.6 2.8 1.1 1.7 8.4 0.9 3.5 2.7 1.7 1.0 3.5 0.8 2.3 8.3 6.1 4.3 1.9 1.0 0.5 0.0 3.2 0.0 0.4 0.4 0.5 1.7 0.1 0.4 0.8 0.0 0.5 1.5 8.0 6.1 10.7 12.5 0.9 1.8 0.1 0.7 5.8 1.3 0.1 4.7 17.9 0.1 0.5 0.0 1.0 2.0 0.8 0.4 1.2 4.7 2.9 3.8 2.0 0.2 0.4 0.0 7.9 0.3 0.8 0.2 0.2 0.0 0.7 0.5 0.2 2.6 0.7 1.3 0.1 0.4 0.7 1.1 0.6 1.0 0.7 8.6 2.0 0.1 4.0 0.0 0.2 0.1 0.0 0.0 10.3 0.0 0.0 0.9 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.2 0.3 0.2 3.2 0.4 0.0 0.0 0.0 0.5 DUSP15 "bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY" ENSG00000149599 "Dual specificity phosphatase 15" Q9H1R2 20 31847637-31870747 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 75.1" "Cell line enhanced" "Detected in some" "CACO-2: 5.3;REH: 17.4;SH-SY5Y: 5.0;SK-MEL-30: 4.3;U-2 OS: 4.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 14 "naive B-cell: 1.6" "Lineage enriched" "Detected in single" 14 "B-cells: 1.6" "Low region specificity" "Detected in all" HPA076649 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA076649: " "unprognostic (3.84e-2)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (9.01e-3)" "unprognostic (3.88e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (1.48e-5)" "unprognostic (7.31e-2)" "prognostic favourable (5.40e-7)" "unprognostic (2.79e-2)" "unprognostic (1.93e-1)" "unprognostic (3.11e-3)" "unprognostic (2.55e-1)" 1.1 2.1 2.8 0.6 4.0 0.5 1.3 1.2 3.7 1.6 0.8 4.2 6.9 0.9 1.4 10.4 0.6 0.7 1.1 2.7 2.8 3.1 15.4 0.6 0.8 1.0 4.9 2.3 2.1 1.8 10.6 2.7 1.1 5.9 1.9 0.5 5.3 2.1 9.3 2.4 0.7 1.0 2.3 5.2 1.0 1.1 75.1 1.4 0.0 3.5 0.1 0.6 0.7 0.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 1.6 0.0 0.3 0.0 0.0 0.0 0.9 0.0 5.3 0.1 1.0 2.2 0.3 0.0 0.4 0.0 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.7 0.7 0.0 17.4 2.0 0.1 0.0 0.0 2.4 5.0 2.8 0.0 4.3 1.3 1.0 0.0 0.0 4.2 0.0 0.0 1.8 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.0 1.2 3.7 2.8 3.1 4.9 2.3 5.9 1.4 DUSP16 "KIAA1700, MKP-7, MKP7" ENSG00000111266 "Dual specificity phosphatase 16" Q9BY84 12 12474210-12562383 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 24.2;RT4: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 6.9" "Lineage enriched" "Detected in many" 5 "T-cells: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020326 Approved Supported Nucleoplasm Nucleoplasm "HPA020326: AB_1847890" "unprognostic (8.05e-2)" "unprognostic (9.47e-2)" "unprognostic (1.49e-3)" "unprognostic (4.14e-2)" "unprognostic (9.86e-2)" "prognostic favourable (1.01e-4)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (2.82e-1)" "unprognostic (2.34e-3)" "unprognostic (6.35e-3)" "unprognostic (2.42e-1)" "unprognostic (1.46e-1)" "unprognostic (5.76e-2)" 6.4 32.8 6.3 14.8 7.5 3.4 12.5 16.4 7.1 8.8 13.1 6.7 9.5 13.6 11.0 9.1 9.5 6.8 12.3 5.8 6.7 5.4 6.6 34.2 17.0 13.2 8.0 3.6 8.5 13.9 11.6 31.4 21.3 7.7 13.9 11.7 9.2 17.4 9.5 8.3 7.9 20.1 5.7 9.1 12.2 9.9 8.6 9.2 40.7 10.8 6.8 16.7 10.9 13.4 0.1 0.2 1.4 0.1 0.1 6.9 0.5 2.7 4.1 5.2 2.7 1.8 2.4 8.7 1.7 3.7 4.1 6.0 12.2 5.3 0.2 0.9 1.8 1.8 9.2 1.5 5.9 8.9 4.6 0.4 4.4 13.6 3.9 0.8 1.9 1.9 4.6 3.3 10.9 3.2 2.4 7.5 0.3 6.0 1.0 0.6 24.2 1.3 1.2 1.7 5.0 2.6 22.0 7.9 7.6 6.6 8.9 4.4 3.4 1.5 2.8 1.9 5.5 1.2 1.9 5.3 6.1 0.9 2.5 1.8 2.6 0.0 0.0 0.0 1.1 0.1 4.6 0.1 3.2 1.5 0.2 0.1 1.1 0.7 1.4 0.1 0.0 0.0 6.9 0.5 6.3 7.5 16.4 7.1 6.7 5.4 8.0 3.6 7.7 9.2 DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667890 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Nucleoplasm "CAB034070: AB_2094867, HPA051349: " "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (3.49e-3)" "unprognostic (4.88e-3)" "unprognostic (1.88e-1)" "unprognostic (9.12e-2)" "unprognostic (3.77e-4)" "unprognostic (1.83e-1)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (9.62e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-3)" "unprognostic (6.55e-2)" "unprognostic (1.97e-1)" "unprognostic (4.56e-2)" "unprognostic (1.02e-1)" 5.2 3.9 10.1 7.1 9.7 4.9 5.3 4.1 8.3 5.6 10.1 11.4 4.6 7.8 6.1 8.4 7.5 18.5 8.0 3.8 8.7 7.8 5.5 2.3 9.9 7.2 8.4 3.9 4.4 6.6 5.2 19.5 3.6 9.5 4.6 11.5 4.7 6.1 4.3 2.0 7.9 11.0 6.4 9.0 6.9 8.3 30.8 10.2 8.0 5.8 3.4 7.6 6.0 6.1 6.4 11.2 21.7 13.9 4.3 8.1 4.7 5.2 5.7 2.6 6.4 6.4 12.9 2.5 5.0 5.7 5.1 5.5 3.1 5.6 3.5 3.5 6.2 3.9 1.6 4.0 5.7 9.8 6.3 1.7 2.0 2.0 2.8 7.3 5.8 3.6 5.7 8.5 3.1 15.5 1.8 3.2 5.5 4.5 4.0 1.8 1.0 3.5 2.9 1.7 1.3 6.1 3.7 6.6 3.8 5.2 2.1 3.7 4.6 2.1 11.2 10.5 5.7 2.7 2.9 2.3 2.6 1.7 11.8 1.3 5.2 18.3 10.4 19.4 5.9 12.5 4.6 6.4 6.8 5.4 11.2 6.2 4.6 5.5 21.7 4.3 13.9 6.4 8.1 4.7 10.1 9.7 4.1 8.3 8.7 7.8 8.4 3.9 9.5 10.2 DUSP19 "DUSP17, SKRP1" ENSG00000162999 "Dual specificity phosphatase 19" Q8WTR2 2 183078559-183100005 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021501 Approved Approved Nucleoplasm Nucleoplasm "HPA021501: AB_1847892" "unprognostic (1.24e-1)" "unprognostic (2.13e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (5.18e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (8.30e-2)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (6.53e-2)" "unprognostic (5.80e-3)" "unprognostic (6.97e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-2)" "unprognostic (2.75e-2)" 2.8 4.6 9.2 2.0 16.3 1.0 3.0 2.9 9.6 3.4 4.7 2.2 3.8 3.5 6.8 9.2 4.2 8.4 3.5 7.4 17.4 3.4 4.7 3.0 3.4 2.3 3.3 6.8 4.4 4.3 7.7 10.6 2.7 3.7 4.2 3.0 3.0 2.8 5.4 3.8 3.4 3.0 8.6 2.9 4.0 9.1 10.4 4.7 6.2 4.6 1.1 1.9 4.0 2.7 4.1 1.5 2.0 0.8 2.2 3.2 1.3 0.1 2.4 2.8 1.4 3.9 2.2 0.0 1.1 1.8 4.5 1.6 2.2 2.9 1.0 5.9 1.2 0.3 5.7 0.8 3.5 5.7 3.1 10.5 1.8 1.6 1.7 2.6 6.5 1.7 0.5 2.3 1.1 2.6 3.1 1.6 2.7 1.0 4.9 2.5 2.4 2.0 4.9 4.5 0.3 1.0 1.1 3.6 1.5 3.9 1.6 2.8 0.8 1.0 2.0 2.4 2.1 1.6 0.9 2.0 2.4 0.1 3.1 0.4 3.7 2.0 0.5 1.9 2.3 0.8 2.3 4.1 2.1 3.1 0.6 2.2 2.7 2.7 1.3 2.2 0.4 1.5 3.2 1.3 9.2 16.3 2.9 9.6 17.4 3.4 3.3 6.8 3.7 4.7 DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143166-96145440 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 151.1" "Cell line enhanced" "Detected in many" "Daudi: 15.3;HeLa: 13.9;Karpas-707: 17.4;NB-4: 14.4;RT4: 17.3;SCLC-21H: 15.5;U-698: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "gdT-cell: 46.1" "Group enriched" "Detected in all" 10 "NK-cells: 29.6;T-cells: 46.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071920 Supported "Nucleoplasm,Nuclear membrane" "Nuclear membrane" Nucleoplasm "HPA071920: " "unprognostic (2.69e-3)" "unprognostic (6.70e-3)" "unprognostic (1.15e-1)" "unprognostic (5.46e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (3.66e-2)" "unprognostic (3.10e-1)" "unprognostic (6.30e-2)" "prognostic unfavourable (4.97e-5)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (1.31e-3)" 6.4 3.1 2.0 13.1 4.3 51.3 2.9 1.3 4.3 4.8 3.9 1.9 7.9 0.8 4.3 18.3 4.1 3.0 8.8 7.4 3.0 1.4 5.5 3.4 15.9 19.0 1.8 0.8 3.0 1.7 0.4 14.6 0.6 2.0 10.7 1.1 2.8 2.0 151.1 1.8 9.8 4.7 3.7 1.6 16.4 2.1 3.3 0.7 43.4 2.4 2.6 12.2 24.6 14.1 3.9 2.3 1.4 2.2 29.6 46.1 7.5 1.5 0.0 0.1 0.1 0.2 0.3 2.2 1.9 0.0 2.8 2.7 4.4 0.3 15.3 5.5 2.1 1.1 3.8 0.0 0.5 0.2 0.0 0.3 13.9 0.0 1.0 6.3 1.3 0.5 1.0 0.4 0.0 0.0 0.0 17.4 0.1 2.6 12.4 14.4 3.4 5.4 0.0 0.2 12.1 0.1 17.3 15.5 0.8 0.7 0.2 2.8 1.0 7.2 0.0 0.0 4.1 0.0 0.8 1.2 1.8 21.0 0.0 6.9 0.1 0.5 0.9 0.2 46.1 2.2 22.6 3.9 11.4 41.4 2.3 2.6 7.8 23.9 1.4 29.6 1.8 0.6 3.4 7.5 2.0 4.3 1.3 4.3 3.0 1.4 1.8 0.8 2.0 0.7 DUSP22 "JKAP, JSP1, MKPX, VHX" ENSG00000112679 "Dual specificity phosphatase 22" Q9NRW4 6 291630-351355 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 70.3;U-266/70: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031394 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA031394: AB_10604114" "unprognostic (7.34e-3)" "unprognostic (7.94e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (3.46e-1)" "unprognostic (1.70e-2)" "unprognostic (9.08e-3)" "unprognostic (2.48e-1)" "unprognostic (9.06e-2)" "unprognostic (5.56e-3)" "unprognostic (3.10e-2)" "unprognostic (3.04e-1)" "unprognostic (1.77e-1)" "unprognostic (3.97e-2)" "unprognostic (3.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.09e-1)" 24.8 13.1 22.0 24.6 31.3 19.4 28.7 12.1 27.5 18.1 29.0 29.8 18.8 21.2 20.6 25.2 29.8 15.0 20.4 31.0 22.6 17.4 16.0 20.3 24.6 27.4 33.5 16.1 13.9 27.9 10.8 14.8 25.9 25.5 16.1 15.9 16.9 20.9 15.5 32.0 30.6 21.8 23.4 29.2 30.0 21.4 41.3 30.0 9.2 19.9 19.0 27.9 22.8 27.4 21.6 18.0 16.3 17.5 2.9 8.2 9.8 3.5 2.2 4.7 7.0 5.4 6.1 6.2 2.6 2.1 2.3 2.8 2.3 4.0 7.5 6.4 2.7 2.5 5.9 4.9 1.7 17.9 6.8 5.1 1.7 6.4 2.8 1.8 6.7 4.5 14.8 1.7 3.1 6.7 4.7 25.2 1.9 2.1 2.6 6.5 2.8 5.1 5.3 3.2 70.3 4.4 1.5 8.1 3.2 2.2 0.9 7.7 4.7 2.3 9.1 2.1 2.8 2.1 1.6 35.8 25.2 10.4 0.8 5.0 4.7 16.3 17.5 6.9 5.0 14.0 3.5 21.6 3.9 5.1 18.0 17.5 3.6 5.1 12.0 2.9 12.6 15.4 8.2 9.8 22.0 31.3 12.1 27.5 22.6 17.4 33.5 16.1 25.5 30.0 DUSP23 "DUSP25, FLJ20442" ENSG00000158716 "Dual specificity phosphatase 23" Q9BVJ7 1 159780932-159782543 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 88.0" "Cell line enhanced" "Detected in many" "HSkMC: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028211, HPA045792" Approved Supported Nucleoplasm Nucleoplasm "HPA028211: , HPA045792: AB_10961133" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-2)" "unprognostic (4.36e-2)" "unprognostic (3.22e-1)" "prognostic unfavourable (3.06e-4)" "unprognostic (3.16e-1)" "unprognostic (4.62e-1)" "unprognostic (3.33e-3)" "unprognostic (4.72e-2)" "unprognostic (3.75e-2)" "prognostic unfavourable (2.59e-5)" "unprognostic (8.58e-2)" "unprognostic (2.84e-2)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" 25.0 28.0 7.6 9.3 10.5 11.2 27.3 4.4 9.0 15.5 15.9 5.9 6.6 17.2 12.2 15.0 21.2 10.9 12.6 14.9 7.8 5.2 88.0 80.8 12.1 15.4 8.5 4.6 12.3 21.5 12.5 4.3 7.4 9.6 18.0 9.1 9.5 37.8 10.9 32.8 15.8 16.1 7.7 9.6 8.7 11.0 9.7 7.3 5.7 27.0 17.4 11.4 10.5 19.1 13.6 59.7 49.9 43.2 21.3 24.0 24.0 12.2 13.2 0.1 0.0 12.9 11.0 0.1 5.0 4.1 5.9 4.6 5.3 14.0 0.0 29.9 5.4 0.5 3.4 4.5 3.2 3.0 1.5 16.8 4.7 0.0 19.2 10.1 12.9 46.6 12.2 3.8 13.8 22.4 7.6 6.1 8.2 22.1 1.0 0.4 22.7 18.8 0.0 0.0 5.7 7.1 2.1 5.7 12.7 9.0 19.9 23.2 12.8 15.9 16.4 4.9 0.2 0.6 0.0 4.3 10.3 0.1 8.3 8.2 3.7 20.0 43.2 49.9 24.0 33.4 13.3 13.6 18.1 22.5 59.7 9.8 11.0 16.4 43.2 21.3 22.1 13.6 15.7 24.0 7.6 10.5 4.4 9.0 7.8 5.2 8.5 4.6 9.6 7.3 DUSP26 "DUSP24, MGC1136" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591332-33600106 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 147.1" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 45.1" "Cancer enhanced" "Detected in some" "glioma: 6.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 16 "B-cells: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm Nucleoplasm "HPA018221: AB_2669813" "unprognostic (2.77e-4)" "unprognostic (2.70e-2)" "unprognostic (2.70e-3)" "unprognostic (5.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-2)" "unprognostic (2.81e-1)" "unprognostic (1.39e-1)" "unprognostic (4.10e-3)" "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.15e-2)" "unprognostic (5.80e-2)" 1.3 9.3 11.5 1.4 13.1 1.1 1.2 18.2 14.8 1.1 1.7 4.2 0.0 2.4 1.5 3.4 3.0 2.3 1.5 20.1 9.1 15.9 1.6 1.0 1.7 1.1 10.6 8.8 15.1 2.2 1.0 14.0 1.0 7.6 2.6 1.5 4.4 1.5 1.3 147.1 1.0 1.9 2.0 10.0 1.2 2.6 1.6 3.8 0.0 1.1 27.0 1.3 1.4 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 45.1 10.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 13.1 18.2 14.8 9.1 15.9 10.6 8.8 7.6 3.8 DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240564014 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB069448: , HPA047456: AB_10961145" "unprognostic (1.88e-2)" "unprognostic (9.29e-2)" "unprognostic (4.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (7.56e-3)" "unprognostic (4.13e-3)" "unprognostic (3.71e-2)" "prognostic favourable (1.84e-4)" "unprognostic (9.85e-2)" "unprognostic (1.80e-3)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-3)" 1.8 2.8 2.7 3.0 3.4 7.9 3.5 6.3 3.7 3.1 2.6 3.3 6.5 2.9 2.6 5.0 3.5 3.1 4.4 16.3 2.8 2.7 3.2 3.4 2.5 6.1 3.5 2.4 2.6 10.2 2.6 5.0 3.2 2.8 4.3 2.8 2.7 3.7 2.4 21.2 4.9 4.2 4.3 2.2 5.9 4.2 8.2 2.3 2.6 4.4 13.4 4.2 2.8 4.5 3.8 3.3 10.7 2.1 2.7 3.3 2.0 1.7 1.6 2.2 2.5 1.4 0.7 2.3 1.9 1.1 1.5 1.1 0.9 4.4 2.7 1.0 1.2 4.9 1.7 0.6 1.6 3.3 6.2 3.8 3.3 2.4 1.0 2.5 6.6 1.6 1.7 1.0 1.3 0.7 2.7 3.2 1.3 1.8 3.1 4.0 1.4 1.4 3.8 4.7 3.6 1.1 2.9 4.8 2.7 1.8 1.9 2.1 2.3 4.3 1.7 3.5 2.8 2.2 1.7 12.9 3.7 4.3 2.1 1.9 2.7 10.7 2.1 0.7 2.7 1.4 3.0 2.1 2.8 2.8 1.2 3.8 3.3 3.0 3.6 2.7 1.5 3.3 2.2 2.0 2.7 3.4 6.3 3.6 2.8 2.7 3.5 2.4 2.8 2.3 DUSP3 VHR ENSG00000108861 "Dual specificity phosphatase 3" P51452 17 43766121-43778988 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 19.5;granulocytes: 5.2;monocytes: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063616 Supported Nucleoplasm,Cytosol 1300000 Nucleoplasm Cytosol "HPA063616: " "unprognostic (1.52e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (1.04e-3)" "prognostic unfavourable (3.00e-4)" "unprognostic (4.83e-2)" "unprognostic (8.98e-2)" "unprognostic (5.13e-1)" "unprognostic (6.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.40e-3)" "prognostic favourable (5.49e-5)" "unprognostic (2.67e-3)" "unprognostic (5.45e-2)" "unprognostic (1.94e-1)" "unprognostic (1.37e-2)" 17.1 17.8 23.1 10.2 20.8 4.6 22.0 14.3 28.6 12.8 28.4 11.1 16.7 13.4 17.5 18.7 23.6 10.6 19.3 64.0 21.5 18.1 27.1 39.9 17.2 9.0 17.6 19.1 9.1 19.2 27.5 11.4 15.0 17.1 22.6 13.1 14.3 11.1 36.6 106.9 8.9 15.2 31.1 12.7 14.5 19.6 8.0 10.8 1.2 13.9 22.8 6.5 20.7 24.1 1.7 19.5 5.2 17.0 0.9 1.7 5.8 10.9 19.8 7.6 8.1 22.3 12.0 6.5 8.3 19.9 19.4 23.5 19.0 7.4 1.7 13.2 15.5 9.5 11.8 10.2 20.5 3.7 9.0 5.5 9.1 15.5 27.3 0.6 5.7 11.1 18.4 14.9 13.1 13.5 4.9 1.9 22.6 7.8 2.8 2.8 3.5 14.5 3.6 23.0 4.1 26.9 11.5 4.3 7.7 9.7 6.5 24.4 29.1 15.4 14.0 22.0 14.9 31.2 13.7 10.2 13.4 0.4 26.1 7.7 7.3 5.2 17.0 3.5 1.0 8.9 1.7 1.7 1.5 1.2 19.5 1.6 1.2 1.1 4.1 0.9 10.8 8.2 0.9 5.8 23.1 20.8 14.3 28.6 21.5 18.1 17.6 19.1 17.1 10.8 DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350668 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 46.7;pancreas: 78.6;seminal vesicle: 63.5" "Cell line enhanced" "Detected in many" "A549: 30.0;SK-MEL-30: 46.2;WM-115: 37.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 8 "T-reg: 9.6" "Lineage enriched" "Detected in single" 18 "T-cells: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061967 Supported Nucleoplasm Nucleoplasm "HPA061967: " "unprognostic (1.92e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "unprognostic (6.54e-2)" "unprognostic (2.18e-2)" "unprognostic (7.66e-3)" "unprognostic (7.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.83e-2)" "unprognostic (9.73e-3)" "unprognostic (9.60e-3)" "unprognostic (3.15e-2)" "prognostic unfavourable (4.19e-4)" "unprognostic (6.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-2)" "unprognostic (6.07e-2)" 10.9 3.4 1.2 3.6 1.1 3.4 17.1 4.8 2.7 4.6 1.7 1.0 46.7 0.8 3.2 0.7 1.6 1.3 13.1 1.5 4.6 0.8 0.7 0.4 3.7 1.8 0.8 0.8 1.2 78.6 0.1 3.7 17.7 0.7 4.3 0.9 17.1 8.9 63.5 2.7 3.5 1.3 1.5 1.1 0.6 20.6 1.7 0.2 3.9 1.2 2.0 4.7 7.4 3.0 0.0 0.5 0.0 0.0 0.2 9.6 0.1 11.1 30.0 17.8 0.8 2.3 0.0 1.5 2.3 12.8 7.0 3.1 0.3 5.7 0.0 6.3 1.0 3.6 0.2 7.7 4.2 0.3 0.6 0.0 1.0 0.2 0.0 0.1 14.6 1.4 5.1 2.2 13.1 5.7 0.1 1.3 14.0 12.6 0.0 2.1 3.1 18.4 0.3 0.6 2.3 16.1 5.9 0.1 9.9 3.2 15.2 46.2 3.2 0.3 16.0 5.2 0.0 0.0 1.6 3.6 0.4 0.0 15.6 2.6 37.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 9.6 0.1 1.2 1.1 4.8 2.7 4.6 0.8 0.8 0.8 0.7 0.2 DUSP6 "MKP-3, PYST1" ENSG00000139318 "Dual specificity phosphatase 6" Q16828 12 89347232-89353271 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 125.0" "Cell line enhanced" "Detected in many" "AN3-CA: 80.6;NB-4: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 125.0" "Group enriched" "Detected in many" 11 "granulocytes: 125.0;monocytes: 79.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017566, HPA053188, HPA064692" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB017566: AB_647991, HPA053188: , HPA064692: " "unprognostic (7.35e-2)" "unprognostic (1.50e-2)" "unprognostic (5.77e-2)" "prognostic favourable (7.21e-4)" "unprognostic (2.35e-3)" "unprognostic (2.10e-3)" "unprognostic (3.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.63e-2)" "unprognostic (1.67e-2)" "unprognostic (3.15e-3)" "unprognostic (2.09e-1)" "unprognostic (5.91e-3)" "unprognostic (1.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-2)" "unprognostic (2.84e-1)" 37.7 7.5 7.2 15.9 11.7 41.3 24.1 3.4 14.7 11.6 12.4 6.2 5.8 6.1 9.8 8.7 12.0 15.4 25.1 16.2 10.5 6.5 17.1 38.4 28.2 13.3 6.9 7.4 7.5 12.2 15.0 13.7 19.7 7.9 17.4 15.3 44.4 64.3 6.3 12.0 8.5 14.6 11.3 7.1 28.4 10.3 4.8 6.4 6.1 21.0 13.3 17.8 15.2 6.9 1.2 9.2 125.0 79.7 1.2 0.9 32.4 1.1 1.1 24.0 80.6 20.8 17.7 0.0 8.7 11.1 1.7 1.3 7.0 1.2 0.0 2.0 3.7 9.3 0.1 21.6 2.5 0.1 0.1 3.6 0.2 11.2 14.7 15.5 39.5 3.4 7.6 15.3 14.3 40.1 0.0 3.8 5.5 0.5 0.5 57.8 14.6 19.7 39.3 3.0 1.5 24.8 23.3 0.4 17.1 0.2 0.1 45.9 1.2 8.6 10.7 5.9 0.1 1.1 4.1 0.6 3.1 0.0 24.5 10.9 37.4 125.0 49.5 22.4 0.9 79.7 0.4 0.2 0.2 0.3 9.2 1.2 0.1 0.3 22.5 1.2 74.4 1.2 0.6 32.4 7.2 11.7 3.4 14.7 10.5 6.5 6.9 7.4 7.9 6.4 DUSP7 "MKP-X, PYST2" ENSG00000164086 "Dual specificity phosphatase 7" Q16829 3 52048919-52056550 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 40.7;hTERT-HME1: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073007 Approved "HPA073007: " "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (6.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (8.67e-3)" "unprognostic (7.38e-3)" "unprognostic (7.74e-3)" "prognostic unfavourable (8.84e-6)" "unprognostic (4.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-2)" "unprognostic (9.46e-2)" 5.5 5.9 7.8 4.3 8.5 1.6 3.7 6.5 19.2 8.6 2.9 15.3 3.4 2.4 5.6 2.4 22.0 4.4 5.3 8.3 7.3 4.8 3.6 2.5 7.0 5.6 9.9 10.0 4.7 4.3 3.9 3.8 8.9 4.9 4.0 2.3 4.6 5.2 5.3 11.4 24.1 3.5 4.2 4.8 10.7 3.7 5.4 9.2 3.2 3.4 15.0 8.6 5.8 14.7 1.0 7.5 1.7 10.7 2.3 8.2 1.7 7.4 1.6 1.9 4.3 6.2 5.4 2.3 7.6 14.5 7.6 5.5 2.0 3.8 2.0 2.1 11.2 8.9 7.2 27.5 5.2 1.7 2.9 9.9 3.8 3.6 5.0 8.8 6.0 5.6 40.7 9.8 34.6 7.2 5.6 6.0 6.0 2.0 6.5 12.4 4.7 13.7 5.5 1.6 5.5 3.1 3.2 2.4 7.0 3.4 3.1 5.3 1.1 21.2 9.4 14.6 9.4 15.3 23.1 2.9 2.7 3.4 8.1 14.9 4.6 0.9 3.9 1.7 6.0 10.7 8.2 1.0 7.2 4.3 5.0 0.6 5.3 4.8 1.4 2.3 10.0 7.5 4.6 1.7 7.8 8.5 6.5 19.2 7.3 4.8 9.9 10.0 4.9 9.2 DUSP8 "C11orf81, FLJ42958, HB5, HVH-5" ENSG00000184545 "Dual specificity phosphatase 8" Q13202 11 1554044-1571920 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2" "Cell line enhanced" "Detected in some" "MCF7: 6.1;SH-SY5Y: 5.4;U-251 MG: 2.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020071 Approved Approved Cytosol Cytosol "HPA020071: AB_1847903" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (4.00e-2)" "unprognostic (1.35e-1)" "unprognostic (7.58e-3)" "unprognostic (6.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (4.04e-3)" "unprognostic (1.82e-1)" "prognostic favourable (2.75e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (8.65e-2)" "unprognostic (6.30e-2)" 6.3 2.2 18.8 3.2 18.8 7.5 3.5 20.0 30.2 1.9 4.3 4.2 1.4 1.7 5.9 4.8 3.5 4.0 5.4 5.7 16.6 9.3 2.6 3.7 3.6 3.5 5.5 11.2 2.2 12.7 1.7 10.8 2.8 5.1 3.0 4.1 2.7 5.1 2.7 6.1 3.2 6.3 9.3 3.6 6.3 4.3 2.4 5.1 0.0 2.6 2.2 2.3 2.7 1.6 0.1 0.1 0.0 0.0 0.0 0.7 0.0 1.8 0.8 1.0 0.1 0.0 0.1 2.2 0.1 1.1 0.4 1.2 0.0 0.0 0.1 0.0 0.3 1.2 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.2 0.4 0.1 0.0 1.8 0.0 6.1 0.0 0.4 0.0 1.9 0.1 0.1 0.7 0.0 0.2 0.0 5.4 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 1.0 2.3 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 18.8 18.8 20.0 30.2 16.6 9.3 5.5 11.2 5.1 5.1 DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "kidney: 23.0;placenta: 63.1" "Cell line enriched" "Detected in some" 9 "Hep G2: 88.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 7 "amygdala: 4.4;basal ganglia: 2.7;cerebral cortex: 3.5;hippocampal formation: 3.7;hypothalamus: 3.6" HPA003336 Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavourable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" 0.2 0.1 3.2 0.2 4.4 0.1 0.3 0.2 2.0 0.2 0.1 0.7 0.0 0.2 0.1 0.3 0.3 0.2 0.1 0.2 2.5 0.6 23.0 0.7 0.2 0.2 1.1 0.6 1.9 0.5 0.1 0.0 63.1 0.9 0.2 0.1 0.0 0.8 1.5 0.1 0.2 0.2 0.1 0.5 0.2 0.2 1.1 0.8 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 8.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.5 0.5 0.0 3.9 0.0 1.8 9.8 0.2 0.0 0.2 1.8 0.0 0.7 88.7 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.5 0.0 0.1 0.2 3.6 0.0 0.0 0.0 0.0 2.2 0.1 0.3 0.5 0.7 0.3 0.1 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 4.4 0.2 2.0 2.5 0.6 1.1 0.6 0.9 0.8 DUT dUTPase ENSG00000128951 "Deoxyuridine triphosphatase" P33316 15 48331011-48343373 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054422, HPA060360" Enhanced Supported Nucleoplasm Nucleoplasm "HPA054422: , HPA060360: " "unprognostic (1.82e-1)" "unprognostic (3.49e-2)" "unprognostic (7.89e-2)" "unprognostic (5.27e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (4.42e-3)" "unprognostic (1.87e-2)" "unprognostic (4.25e-1)" "unprognostic (3.54e-2)" "unprognostic (3.68e-2)" "unprognostic (4.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-2)" "unprognostic (1.71e-2)" 26.9 32.9 23.2 51.1 31.8 69.0 31.9 31.7 27.6 26.8 26.3 24.4 27.2 14.5 29.8 31.8 33.7 26.9 28.2 35.5 23.2 26.5 25.4 19.8 25.7 44.7 25.3 23.6 33.4 22.2 23.7 30.7 26.0 22.5 30.3 24.3 28.1 27.5 26.1 25.6 27.3 22.6 25.6 23.9 30.1 25.8 31.9 20.7 120.3 40.5 37.7 43.2 23.5 28.4 34.5 32.3 17.0 24.5 22.2 40.2 24.3 25.6 8.1 19.7 18.7 13.8 14.8 11.7 27.2 17.4 25.2 31.3 9.3 17.7 71.6 14.7 14.9 35.3 20.6 18.6 24.7 50.4 21.3 58.4 21.3 12.6 7.7 61.2 27.8 9.0 12.7 17.0 9.0 16.7 31.6 40.7 18.5 10.4 54.7 72.1 12.4 15.6 44.6 43.2 75.2 16.5 17.4 28.6 29.1 20.2 16.4 23.3 23.1 48.9 13.8 26.4 25.5 31.4 35.7 32.9 68.3 70.5 20.0 105.1 28.9 11.3 19.5 17.0 21.7 19.3 28.1 34.5 38.9 34.2 28.2 31.6 40.2 26.5 11.1 22.2 24.5 32.3 34.4 24.3 23.2 31.8 31.7 27.6 23.2 26.5 25.3 23.6 22.5 20.7 DYRK1A "DYRK, DYRK1, MNBH" ENSG00000157540 "Dual specificity tyrosine phosphorylation regulated kinase 1A" Q13627 21 37365573-37526358 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015323, HPA015810" Approved Approved "Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoli fibrillar center" "HPA015323: AB_1847922, HPA015810: AB_1847921" "unprognostic (2.71e-1)" "unprognostic (3.35e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-2)" "unprognostic (4.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (9.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (9.95e-2)" "unprognostic (7.39e-2)" "unprognostic (9.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (3.14e-1)" "unprognostic (1.40e-2)" 20.0 18.5 19.2 23.4 20.0 49.7 19.9 31.6 24.6 23.7 23.0 16.3 17.6 15.4 24.4 18.7 16.8 19.4 19.0 23.2 18.8 17.9 16.9 16.1 24.8 27.3 15.5 17.8 25.7 17.8 31.0 25.1 25.0 14.0 17.6 18.1 18.5 18.7 22.7 39.8 20.1 18.7 22.7 13.8 24.1 18.5 23.5 16.3 60.9 22.7 17.4 22.1 22.7 29.3 3.0 3.3 6.0 2.5 1.3 3.8 0.8 10.2 8.0 16.3 11.5 7.8 8.5 14.5 9.1 11.7 9.3 9.8 11.4 9.0 13.8 6.2 16.0 7.0 11.9 8.9 10.9 21.1 5.1 40.8 13.3 6.9 11.7 16.1 15.0 8.6 10.6 12.0 18.5 9.6 15.4 32.0 9.6 10.3 21.1 11.0 17.3 4.8 27.4 9.0 12.7 9.7 13.4 16.9 9.4 20.8 14.3 14.3 13.4 15.0 12.3 12.7 3.8 7.9 7.6 21.8 16.9 19.8 10.1 18.2 13.8 5.5 1.5 2.0 3.4 2.1 2.1 2.8 3.6 2.6 1.8 3.0 3.8 3.7 6.0 1.3 2.5 3.3 3.1 0.8 19.2 20.0 31.6 24.6 18.8 17.9 15.5 17.8 14.0 16.3 DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.1" "Cell line enhanced" "Detected in many" "SCLC-21H: 12.1;SH-SY5Y: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported Nucleoplasm Nucleoplasm "HPA028522: , HPA028786: AB_10670831" "unprognostic (2.22e-2)" "unprognostic (9.86e-2)" "unprognostic (4.55e-2)" "unprognostic (3.45e-3)" "unprognostic (1.96e-1)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.39e-1)" "unprognostic (6.02e-2)" "unprognostic (3.67e-2)" "unprognostic (8.93e-2)" "unprognostic (4.22e-2)" "prognostic favourable (8.83e-4)" "unprognostic (9.73e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-2)" "unprognostic (3.88e-2)" 4.8 7.9 7.4 3.7 10.2 5.0 4.0 10.1 13.1 4.5 4.2 7.4 6.1 6.2 6.4 12.3 6.7 8.0 4.6 9.0 6.6 6.1 6.1 3.2 5.4 5.1 4.4 6.7 6.1 5.2 7.1 12.3 3.8 6.4 5.5 3.4 6.7 5.5 5.8 89.1 6.3 5.1 3.9 3.4 5.9 5.2 28.8 4.6 11.2 6.4 25.3 5.3 5.6 4.1 4.7 8.3 4.8 3.2 6.2 7.0 2.6 0.4 8.6 8.3 5.9 4.7 4.5 0.7 2.7 1.7 2.5 2.2 0.8 3.3 1.3 10.6 3.2 2.9 1.2 1.9 2.2 4.9 7.2 0.6 5.3 0.8 4.0 0.3 1.8 6.0 1.2 0.8 2.8 0.6 1.3 1.9 0.4 4.2 1.9 0.7 2.0 1.9 0.9 0.1 0.6 5.4 2.1 12.1 13.7 4.2 4.2 0.2 4.1 0.5 4.2 1.1 1.9 0.9 0.8 3.1 1.0 0.9 7.1 0.8 0.4 1.2 3.1 3.2 5.9 3.2 7.0 4.7 4.0 5.9 3.5 3.5 2.2 3.5 4.8 6.2 2.9 8.3 4.2 2.6 7.4 10.2 10.1 13.1 6.6 6.1 4.4 6.7 6.4 4.6 DYRK2 ENSG00000127334 "Dual specificity tyrosine phosphorylation regulated kinase 2" Q92630 12 67648338-67665406 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027230, HPA056902" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA027230: AB_1847925, HPA056902: " "unprognostic (5.86e-3)" "unprognostic (4.18e-1)" "unprognostic (4.08e-3)" "unprognostic (2.56e-3)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (7.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" 12.2 5.3 4.5 20.1 4.8 8.6 8.1 4.4 6.6 10.1 21.3 4.1 8.3 13.7 14.6 9.6 9.6 9.1 16.9 26.1 4.7 3.2 6.3 4.6 10.1 17.9 4.0 3.3 7.6 8.5 3.6 4.4 13.0 5.0 7.1 15.3 6.6 7.2 6.6 23.7 9.4 26.0 11.2 5.3 10.3 14.0 4.4 3.9 34.3 7.6 12.5 17.2 11.1 12.2 2.7 1.9 5.9 1.3 6.9 6.8 1.6 13.5 7.7 11.5 8.3 5.8 7.9 9.2 13.8 9.0 6.8 3.9 10.1 7.5 25.4 17.1 20.0 15.9 9.2 5.4 7.3 10.9 12.0 4.1 5.1 3.8 2.2 9.2 8.9 6.5 7.8 18.2 14.6 3.8 5.0 13.3 8.6 7.8 7.9 4.5 10.0 12.4 21.1 11.4 11.2 7.9 17.1 15.2 18.0 5.8 7.8 8.0 5.3 7.8 5.6 10.8 10.2 7.4 10.9 6.3 1.0 14.1 10.4 6.3 11.1 3.2 0.5 5.9 5.2 1.3 4.0 2.7 3.9 6.8 1.9 2.7 3.3 6.1 0.7 6.9 1.3 0.8 3.1 1.6 4.5 4.8 4.4 6.6 4.7 3.2 4.0 3.3 5.0 3.9 DYRK3 "hYAK3-2, RED, REDK" ENSG00000143479 "Dual specificity tyrosine phosphorylation regulated kinase 3" O43781 1 206635536-206684419 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.2" "Cell line enhanced" "Detected in many" "hTERT-HME1: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15 "plasmacytoid DC: 6.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA075041 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA075041: " "unprognostic (6.51e-2)" "unprognostic (1.24e-2)" "unprognostic (3.36e-2)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-4)" "unprognostic (2.69e-1)" "unprognostic (3.91e-1)" "unprognostic (2.71e-1)" "unprognostic (2.79e-3)" "unprognostic (2.52e-1)" "prognostic unfavourable (9.41e-7)" "unprognostic (2.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (7.62e-3)" 7.1 2.7 4.2 4.2 3.5 6.2 7.7 1.3 2.7 5.6 2.7 2.6 3.7 1.2 7.6 5.1 2.7 6.2 12.8 16.3 6.0 3.4 3.4 7.4 5.0 1.6 2.6 2.0 7.6 5.2 2.8 11.2 1.2 4.6 4.5 1.5 4.1 5.5 3.0 2.1 2.0 2.1 7.5 2.7 1.8 3.7 38.2 3.1 5.1 11.9 3.0 1.7 5.4 7.6 0.0 6.1 0.0 0.1 0.0 0.3 0.0 2.5 3.4 0.8 4.8 8.6 7.7 0.1 8.1 17.9 7.4 9.6 0.2 1.2 3.7 1.2 9.5 0.7 4.2 6.5 7.9 0.0 2.8 5.4 4.4 0.8 13.7 3.7 3.5 5.4 4.2 12.8 35.2 5.7 10.3 0.7 11.4 0.9 8.1 2.1 6.8 6.4 20.2 2.6 0.0 2.3 0.1 4.9 3.6 7.3 0.3 9.9 0.9 0.9 4.3 15.5 5.9 7.5 6.7 2.9 1.0 4.4 9.2 4.1 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 4.2 3.5 1.3 2.7 6.0 3.4 2.6 2.0 4.6 3.1 DYRK4 ENSG00000010219 "Dual specificity tyrosine phosphorylation regulated kinase 4" Q9NR20 12 4562204-4615302 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "testis: 85.9" "Cell line enhanced" "Detected in many" "HHSteC: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028065, HPA056073" Enhanced Enhanced Vesicles Vesicles "HPA028065: AB_10601212, HPA056073: AB_2683028" "unprognostic (2.50e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (3.56e-3)" "unprognostic (2.62e-1)" "unprognostic (4.07e-3)" "unprognostic (2.03e-2)" "unprognostic (4.69e-2)" "unprognostic (1.29e-1)" "unprognostic (7.13e-2)" "unprognostic (1.22e-2)" "unprognostic (2.46e-1)" "prognostic unfavourable (6.52e-6)" "unprognostic (1.86e-1)" "unprognostic (9.71e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" 1.6 2.1 2.3 2.1 1.8 1.6 2.8 1.9 2.3 2.6 2.1 2.2 2.3 1.7 2.5 9.1 1.6 2.0 1.7 1.7 1.8 1.8 1.9 2.0 2.2 2.5 1.9 2.5 2.2 2.3 2.9 2.7 2.9 2.3 2.3 2.7 2.4 2.3 3.4 1.6 1.9 2.4 2.1 2.7 4.3 1.7 85.9 2.1 1.6 4.3 1.6 2.0 2.4 1.6 7.6 2.7 1.3 5.2 1.1 1.6 1.6 1.9 3.0 3.9 4.2 5.9 7.2 4.6 2.3 4.7 5.3 5.8 0.6 3.1 5.8 0.3 6.6 4.0 2.9 4.3 4.2 4.4 6.6 4.0 0.8 3.3 16.6 3.5 3.2 4.9 9.3 3.7 12.3 7.5 1.6 6.6 4.8 4.0 3.2 8.6 5.2 1.8 0.7 2.8 2.5 6.5 1.9 0.0 1.5 0.4 2.3 3.3 1.8 3.1 0.5 6.3 4.9 0.6 2.9 1.9 2.3 3.4 3.3 5.4 3.2 0.6 2.8 1.3 1.0 2.2 1.1 7.6 1.5 1.6 2.7 5.8 1.6 1.6 0.1 1.1 5.2 1.4 1.1 1.6 2.3 1.8 1.9 2.3 1.8 1.8 1.9 2.5 2.3 2.1 DZIP3 "hRUL138, PPP1R66" ENSG00000198919 "DAZ interacting zinc finger protein 3" Q86Y13 3 108589682-108694846 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 57.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035066, HPA049232" Approved Approved Vesicles Vesicles "HPA035066: AB_10601549, HPA049232: " "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (7.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (3.33e-1)" "unprognostic (5.16e-2)" "unprognostic (2.74e-1)" "unprognostic (3.76e-2)" "unprognostic (2.59e-3)" "unprognostic (5.38e-2)" "prognostic favourable (3.65e-4)" "unprognostic (6.06e-2)" "unprognostic (2.78e-2)" "unprognostic (5.51e-3)" "unprognostic (3.81e-2)" 4.6 9.3 14.1 4.5 25.7 3.1 5.0 14.5 23.7 5.2 4.4 5.8 2.1 2.8 7.4 9.7 3.8 17.4 5.4 10.8 13.2 18.5 10.5 3.9 6.0 8.4 10.3 16.0 10.3 4.9 10.3 57.4 4.5 20.3 9.2 4.5 4.0 3.3 7.0 10.1 3.4 3.6 7.9 9.2 7.0 6.0 29.9 8.0 10.4 12.0 2.8 7.0 5.0 3.5 6.8 1.8 5.2 1.6 11.7 6.5 1.8 6.6 6.0 17.2 10.3 7.6 8.0 5.9 4.2 8.3 7.0 9.5 8.4 4.5 12.0 9.0 4.4 2.5 9.8 3.6 14.8 4.4 4.2 5.5 2.3 5.8 4.6 2.1 3.1 8.3 1.9 6.5 8.1 4.3 5.2 5.9 13.2 6.0 5.3 2.3 10.5 4.3 6.9 14.2 1.1 5.8 3.2 11.7 11.2 7.0 0.7 7.5 10.3 1.9 5.0 6.3 9.6 1.2 3.6 6.8 3.9 23.3 4.8 1.7 7.6 5.2 0.7 1.4 5.0 1.0 6.0 6.8 5.1 6.1 0.6 6.0 4.5 6.0 0.1 11.7 1.6 1.8 6.5 1.8 14.1 25.7 14.5 23.7 13.2 18.5 10.3 16.0 20.3 8.0 E4F1 E4F ENSG00000167967 "E4F transcription factor 1" Q66K89 16 2223566-2235742 "Enzymes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, Growth regulation, Host-virus interaction, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052042, HPA069007, HPA071325, HPA072309" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA052042: , HPA069007: , HPA071325: , HPA072309: " "unprognostic (3.05e-1)" "prognostic favourable (9.13e-4)" "unprognostic (7.31e-2)" "unprognostic (4.57e-3)" "unprognostic (2.89e-1)" "prognostic favourable (1.10e-4)" "unprognostic (9.16e-2)" "unprognostic (4.23e-2)" "unprognostic (3.08e-1)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (8.49e-3)" "prognostic unfavourable (5.50e-4)" "unprognostic (1.85e-1)" "unprognostic (1.03e-1)" "unprognostic (5.12e-1)" "unprognostic (8.93e-3)" 12.4 12.8 18.1 13.8 15.4 21.0 21.0 26.1 18.9 10.8 10.7 11.9 9.3 13.4 14.8 10.4 11.4 10.9 13.5 9.8 14.3 10.7 11.7 12.9 10.0 13.4 16.7 16.4 13.8 17.0 11.6 14.8 12.0 12.8 15.5 5.0 8.7 20.7 13.7 26.7 23.2 14.7 10.3 9.8 18.8 15.9 14.6 17.2 13.3 17.3 9.3 10.6 10.5 13.4 11.5 11.6 15.2 14.2 8.5 14.7 9.3 6.1 11.7 5.0 9.7 2.9 2.6 11.8 8.5 4.0 6.0 4.0 18.8 9.5 9.0 9.3 3.3 8.4 4.1 4.4 1.1 9.7 14.6 6.4 18.9 10.1 5.7 8.1 11.3 4.0 5.0 5.4 2.5 4.0 14.8 6.3 2.2 17.0 10.5 17.2 11.1 10.9 19.6 5.4 15.5 3.7 4.4 12.5 9.2 10.4 13.1 6.0 11.3 11.5 7.1 7.1 9.4 7.0 7.2 12.3 5.9 18.1 3.0 5.7 7.2 7.5 10.7 14.6 14.7 13.1 12.5 11.5 12.0 13.6 11.6 11.5 13.2 11.9 15.2 8.5 14.2 7.0 14.1 9.3 18.1 15.4 26.1 18.9 14.3 10.7 16.7 16.4 12.8 17.2 EARS2 "KIAA1970, MSE1" ENSG00000103356 "Glutamyl-tRNA synthetase 2, mitochondrial" Q5JPH6 16 23522014-23557731 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043289, HPA043633" Approved Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA043289: AB_10963932, HPA043633: AB_10959901" "unprognostic (3.10e-2)" "unprognostic (1.60e-1)" "unprognostic (3.65e-3)" "unprognostic (4.20e-1)" "unprognostic (3.57e-1)" "unprognostic (4.64e-2)" "unprognostic (2.73e-1)" "unprognostic (2.91e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" "prognostic unfavourable (7.20e-4)" "unprognostic (8.09e-2)" "prognostic favourable (3.16e-6)" "unprognostic (2.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.19e-1)" "unprognostic (4.29e-2)" 8.4 19.0 11.0 8.5 19.0 2.7 13.6 13.4 16.8 11.1 10.0 10.8 12.7 6.4 11.4 10.2 10.5 13.1 7.8 14.9 10.9 11.9 14.5 18.3 7.3 8.1 9.9 14.0 12.0 18.9 32.7 10.9 12.4 10.3 11.3 11.0 8.8 16.4 11.7 17.3 11.1 6.9 8.3 9.3 7.6 9.2 12.6 10.4 6.3 14.5 9.0 11.0 8.6 16.9 3.0 6.2 0.5 5.5 10.6 7.9 3.3 8.1 16.4 7.7 12.4 5.4 7.8 9.4 9.0 6.9 11.2 9.4 11.9 8.2 11.3 9.3 8.3 9.1 29.1 16.6 10.7 4.5 14.1 6.5 10.1 20.2 8.7 7.2 8.2 8.3 9.9 10.0 14.2 5.0 20.3 6.0 7.9 17.1 7.2 5.2 20.4 5.7 12.9 8.9 21.7 14.1 7.0 13.8 10.1 7.1 13.4 7.2 18.1 8.2 4.0 8.8 7.8 9.7 11.4 11.0 10.4 9.1 9.0 10.1 13.0 0.0 2.8 0.3 4.2 3.6 7.9 3.0 4.7 4.3 6.2 3.0 4.6 4.5 0.5 10.6 5.5 4.5 3.4 3.3 11.0 19.0 13.4 16.8 10.9 11.9 9.9 14.0 10.3 10.4 EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "Emopamil binding protein (sterol isomerase)" Q15125 X 48521158-48528716 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease mutation, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" 3.7 33.2 5.3 4.3 5.7 10.5 10.5 10.1 6.3 8.6 19.6 2.8 3.4 17.2 4.0 3.7 20.6 3.9 4.5 21.7 4.7 4.3 12.8 74.1 14.9 13.0 3.5 8.0 4.8 11.7 6.0 3.7 4.2 8.8 8.6 15.7 5.2 8.7 4.8 3.5 9.1 30.0 5.6 7.0 7.9 8.1 5.4 2.8 9.0 4.6 9.8 10.4 5.0 10.0 17.1 22.9 21.5 12.6 13.3 29.9 18.1 33.0 7.0 18.6 11.1 10.4 7.7 6.0 8.5 7.1 11.3 16.3 13.9 55.3 17.9 6.0 5.9 37.3 31.1 45.9 8.6 13.7 15.5 9.0 9.4 11.9 7.6 33.2 22.4 7.5 16.7 15.1 11.2 7.5 11.5 17.0 9.2 14.5 18.4 20.4 18.6 23.0 12.8 1.8 50.7 27.6 5.9 15.8 8.0 31.3 16.1 4.4 17.7 7.9 7.8 5.8 9.8 22.4 9.2 7.3 11.4 18.1 13.5 33.5 5.5 17.4 8.9 21.5 29.9 11.7 25.1 17.1 22.2 27.5 12.3 12.6 20.1 25.5 1.8 13.3 12.6 22.9 22.4 18.1 5.3 5.7 10.1 6.3 4.7 4.3 3.5 8.0 8.8 2.8 ECE1 ECE ENSG00000117298 "Endothelin converting enzyme 1" P42892 1 21217247-21345504 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 114.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 101.6;TIME: 90.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 21.5" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001490, HPA013616" Enhanced 2100000 "HPA001490: AB_1078718, HPA013616: AB_1847963" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (1.49e-2)" "unprognostic (1.46e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (9.10e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-2)" 44.0 49.9 10.3 18.7 14.5 17.3 33.7 3.6 15.6 29.5 27.5 19.2 11.2 12.4 24.0 10.5 15.6 19.1 23.0 30.9 12.4 8.0 14.9 41.8 30.1 14.4 13.9 13.4 34.2 42.1 114.4 21.6 27.0 14.6 27.9 14.6 26.5 14.7 11.4 15.2 14.8 23.2 24.1 13.2 23.5 18.9 19.1 14.7 9.5 23.2 10.7 19.1 34.2 37.0 4.6 2.0 21.5 7.5 1.0 6.1 4.2 13.6 9.2 11.8 5.9 17.1 18.2 6.8 20.3 35.5 11.1 10.2 6.6 42.0 4.9 51.2 20.5 5.8 4.8 9.7 9.7 12.4 4.0 7.1 14.2 5.3 22.8 1.0 1.8 9.5 11.4 17.1 8.5 101.6 1.4 2.6 9.4 2.8 2.0 1.6 3.6 7.2 2.5 6.8 7.1 17.3 2.5 4.0 9.8 20.2 11.9 8.8 8.5 2.9 90.1 25.0 12.2 11.0 11.7 4.1 6.9 5.7 52.0 2.4 30.2 0.1 5.8 2.2 2.2 7.5 3.3 4.6 4.6 3.5 0.5 3.1 3.1 1.9 21.5 1.0 5.2 2.0 6.1 4.2 10.3 14.5 3.6 15.6 12.4 8.0 13.9 13.4 14.6 14.7 ECEL1 "DINE, XCE" ENSG00000171551 "Endothelin converting enzyme like 1" O95672 2 232479827-232487828 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.6;ovary: 57.1" "Group enriched" "Detected in some" 6 "AN3-CA: 29.4;HeLa: 15.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.9" "Region enriched" "Detected in many" 5 "hypothalamus: 28.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA067560, HPA069756, HPA077424" Approved Supported Approved "Nucleoplasm,Nuclear membrane,Nucleoli" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA067560: , HPA069756: , HPA077424: " "unprognostic (1.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.39e-1)" "unprognostic (4.62e-3)" "unprognostic (2.80e-1)" "unprognostic (9.96e-4)" "unprognostic (7.56e-3)" "unprognostic (1.22e-1)" "unprognostic (9.89e-3)" "unprognostic (8.49e-2)" "unprognostic (1.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.24e-5)" "unprognostic (3.09e-2)" "unprognostic (3.68e-1)" "unprognostic (7.84e-2)" "unprognostic (5.45e-2)" 0.9 2.6 0.5 0.9 4.0 0.2 0.4 0.7 1.2 0.3 0.4 0.5 0.1 0.3 0.6 4.9 0.3 1.7 1.0 1.1 0.1 28.6 1.0 0.7 0.2 1.2 0.3 0.1 57.1 0.6 0.3 8.9 0.4 5.5 0.3 0.2 11.5 0.3 1.2 1.8 0.3 0.3 1.1 4.5 2.0 0.3 0.8 1.6 0.1 0.5 0.3 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 29.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.3 0.0 0.0 0.4 0.0 0.0 0.0 2.6 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.0 0.7 1.2 0.1 28.6 0.3 0.1 5.5 1.6 ECHDC1 dJ351K20.2 ENSG00000093144 "Ethylmalonyl-CoA decarboxylase 1" Q9NTX5 6 127288710-127343609 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035445, HPA035446" Uncertain Approved Vesicles Vesicles "HPA035445: AB_10669860, HPA035446: " "unprognostic (9.57e-2)" "unprognostic (1.63e-2)" "unprognostic (2.46e-3)" "unprognostic (1.34e-1)" "unprognostic (4.09e-1)" "unprognostic (3.68e-2)" "unprognostic (5.03e-3)" "unprognostic (4.89e-3)" "unprognostic (4.97e-2)" "unprognostic (1.76e-1)" "unprognostic (3.99e-1)" "unprognostic (9.97e-2)" "unprognostic (8.21e-3)" "unprognostic (6.83e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.40e-2)" 40.1 16.8 20.8 16.5 23.1 6.8 21.9 16.6 21.4 18.6 27.2 12.0 12.8 21.9 13.7 15.5 20.6 11.4 16.1 20.0 19.4 18.0 44.4 44.3 26.8 17.8 27.3 16.5 11.9 14.2 14.5 16.1 17.0 23.1 19.8 26.3 15.1 22.2 14.5 22.0 13.3 25.8 30.1 27.3 14.1 18.1 8.3 20.9 20.7 42.4 14.2 19.4 24.2 22.6 13.2 29.6 13.4 31.2 6.4 11.6 16.9 15.8 12.6 18.1 16.7 27.0 25.7 15.4 25.8 31.5 22.3 28.5 21.9 12.1 24.0 22.3 24.5 13.1 0.0 19.4 28.3 14.2 12.1 31.9 17.0 34.8 24.1 42.6 18.0 28.9 23.4 20.8 17.7 20.1 39.5 14.6 29.7 14.9 28.1 19.8 15.0 15.7 13.3 22.4 19.6 40.6 19.6 20.9 20.3 14.5 0.5 35.5 0.5 49.9 20.8 13.7 22.0 34.6 28.8 18.7 37.6 31.6 25.1 37.4 32.2 6.2 31.2 10.0 11.0 25.6 11.6 12.8 9.5 10.8 29.6 13.2 11.6 11.6 13.4 6.4 17.9 22.6 9.6 16.9 20.8 23.1 16.6 21.4 19.4 18.0 27.3 16.5 23.1 20.9 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362480-133373689 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria 1500000 Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favourable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 36.5 18.7 16.6 9.1 16.6 5.0 15.2 8.2 18.3 8.8 21.8 13.0 34.7 22.8 9.5 14.1 16.5 12.2 17.4 29.8 14.6 11.5 62.1 148.2 6.3 7.8 14.8 10.3 11.6 16.3 9.2 11.0 12.8 11.1 13.9 14.0 11.0 40.2 38.4 35.7 8.8 32.1 9.9 11.9 7.3 11.0 10.2 10.2 3.9 16.2 17.5 13.0 11.2 7.8 39.4 53.7 18.3 45.7 33.5 32.1 44.5 28.7 36.1 19.7 49.1 28.6 18.4 18.0 21.2 28.0 29.6 25.1 79.2 28.0 21.7 18.4 23.8 27.0 25.5 21.5 21.4 16.6 44.8 21.6 21.8 56.3 24.0 28.0 15.4 20.5 18.6 19.6 25.1 26.2 19.5 19.1 28.8 68.2 13.9 54.7 13.7 43.4 24.0 23.9 11.6 36.5 36.9 12.7 20.2 21.9 36.4 27.5 28.3 27.0 21.0 13.4 19.4 27.7 27.9 14.4 8.8 24.6 31.7 15.3 11.0 17.0 41.7 18.3 24.9 45.7 32.1 39.4 28.1 27.1 53.7 32.2 28.9 27.9 4.4 33.5 34.3 23.2 26.0 44.5 16.6 16.6 8.2 18.3 14.6 11.5 14.8 10.3 11.1 10.2 ECI1 DCI ENSG00000167969 "Enoyl-CoA delta isomerase 1" P42126 16 2239395-2252300 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 90.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041746, HPA043227" Enhanced Enhanced Mitochondria 11000000 Mitochondria "HPA041746: AB_10960693, HPA043227: AB_10960273" "unprognostic (4.99e-2)" "prognostic favourable (3.04e-5)" "unprognostic (3.75e-1)" "unprognostic (2.92e-3)" "unprognostic (8.90e-2)" "unprognostic (2.85e-2)" "prognostic favourable (1.07e-4)" "unprognostic (1.98e-1)" "unprognostic (2.17e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-2)" "unprognostic (2.66e-2)" "prognostic favourable (8.99e-8)" "unprognostic (2.61e-2)" "unprognostic (3.31e-1)" "unprognostic (1.97e-1)" "unprognostic (6.08e-3)" 15.7 12.5 12.5 9.8 10.8 9.1 16.8 12.8 11.3 10.9 27.6 9.7 20.3 30.9 10.6 16.7 15.5 13.4 17.3 56.4 10.1 10.3 36.5 57.4 10.3 10.7 12.4 8.8 10.8 30.4 11.1 11.9 10.6 13.0 13.4 8.4 16.3 40.9 19.1 90.3 10.4 31.2 14.1 10.1 8.0 17.2 8.4 9.6 10.4 38.7 25.4 10.5 14.4 11.5 7.6 6.5 3.9 7.1 5.8 6.7 1.7 7.3 17.5 6.7 27.6 2.6 3.6 25.3 7.4 5.1 6.1 9.0 30.9 22.5 10.6 18.6 4.6 18.1 7.9 7.0 0.8 18.4 40.4 3.2 16.4 38.1 23.6 9.5 1.5 6.8 16.7 5.0 11.0 6.1 17.6 22.6 2.0 30.2 0.9 14.3 15.6 17.8 33.4 7.3 51.1 11.6 8.3 23.2 14.7 17.9 33.9 22.4 21.8 17.0 5.0 4.8 18.0 5.1 8.2 25.0 14.7 17.3 6.3 8.9 6.7 3.2 6.8 2.7 3.8 7.1 6.0 7.6 5.5 2.9 5.5 7.4 6.7 5.6 3.9 5.8 4.2 6.5 6.7 1.7 12.5 10.8 12.8 11.3 10.1 10.3 12.4 8.8 13.0 9.6 ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115689-4135597 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 102.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria "Peroxisomes, Mitochondria" "HPA022130: AB_1855176, HPA031626: AB_2673965" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-2)" "unprognostic (1.00e-2)" "prognostic unfavourable (2.85e-4)" "unprognostic (1.17e-3)" "unprognostic (4.97e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-3)" "unprognostic (3.17e-2)" "unprognostic (5.75e-2)" "prognostic favourable (2.04e-6)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-2)" "unprognostic (1.34e-1)" 17.9 29.2 13.2 7.3 17.4 4.5 17.0 8.9 9.5 15.7 18.0 10.7 14.9 16.2 15.2 26.2 10.6 12.7 12.4 32.1 10.3 11.1 56.8 102.3 7.4 8.9 13.3 7.2 19.0 59.2 8.9 17.2 11.1 10.3 14.6 14.0 13.3 9.0 10.5 45.7 5.6 22.7 10.3 11.9 10.1 23.2 11.9 9.3 13.3 17.7 26.6 7.5 12.6 8.9 20.6 25.1 7.0 16.2 25.5 27.7 16.7 17.8 9.7 16.3 35.4 20.5 30.5 2.0 25.3 26.0 27.7 24.8 7.3 2.7 0.7 31.9 27.5 9.4 18.5 14.7 40.3 6.7 21.2 9.4 13.8 39.3 11.9 8.5 4.7 21.0 9.1 23.5 13.2 57.6 30.8 6.9 26.2 7.1 24.0 21.2 11.0 34.9 23.3 20.2 0.3 14.9 3.6 0.3 7.6 1.5 10.6 22.4 24.5 4.0 58.1 20.9 11.5 18.4 15.0 10.6 18.8 1.8 10.7 7.5 16.1 6.9 15.5 7.0 18.9 11.5 25.9 19.9 22.3 26.4 25.1 20.6 27.7 27.1 0.4 25.5 16.2 19.2 23.6 16.7 13.2 17.4 8.9 9.5 10.3 11.1 13.3 7.2 10.3 9.3 EDEM3 C1orf22 ENSG00000116406 "ER degradation enhancing alpha-mannosidase like protein 3" Q9BZQ6 1 184690231-184754913 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025754, HPA025755, HPA027297" Approved Approved "Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "HPA025754: AB_1845638, HPA025755: AB_1845639, HPA027297: " "unprognostic (1.74e-1)" "unprognostic (1.64e-2)" "unprognostic (3.08e-2)" "unprognostic (2.67e-2)" "unprognostic (2.30e-1)" "unprognostic (3.10e-2)" "unprognostic (7.52e-3)" "unprognostic (1.82e-1)" "unprognostic (7.06e-2)" "unprognostic (1.66e-1)" "unprognostic (1.66e-1)" "unprognostic (3.53e-2)" "prognostic unfavourable (1.63e-6)" "unprognostic (4.72e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-2)" "unprognostic (2.01e-1)" 12.5 12.6 10.8 11.3 13.8 6.4 11.1 15.2 11.8 13.2 17.6 7.5 10.8 16.0 11.7 7.7 10.9 10.2 10.4 10.4 9.1 8.2 9.6 27.8 13.3 8.9 13.5 8.4 8.8 27.3 18.4 26.4 17.9 10.6 12.3 21.3 7.6 18.3 14.3 20.8 7.1 14.4 10.6 13.3 9.5 31.3 6.2 11.5 15.8 11.5 6.3 10.6 11.6 16.1 2.7 5.9 7.4 6.8 4.0 6.3 3.4 6.5 4.9 6.8 6.0 24.9 25.7 11.1 13.3 9.2 5.1 5.3 2.6 18.9 4.6 14.5 10.0 8.9 6.5 6.9 7.5 4.4 5.3 6.0 5.2 3.7 9.6 15.6 8.8 14.6 8.5 12.3 11.0 13.6 15.7 21.3 9.6 5.4 12.5 8.2 9.5 4.6 5.5 5.2 15.5 7.3 4.6 7.7 10.9 6.5 11.3 9.2 10.6 24.6 15.9 7.3 3.3 15.4 11.1 32.7 12.6 6.0 9.7 17.9 15.9 7.4 6.8 4.1 2.9 6.7 5.1 2.7 4.5 3.5 5.9 2.0 6.3 3.3 6.9 4.0 6.3 3.0 3.0 3.4 10.8 13.8 15.2 11.8 9.1 8.2 13.5 8.4 10.6 11.5 EEF2K eEF-2K ENSG00000103319 "Eukaryotic elongation factor 2 kinase" O00418 16 22206282-22288732 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 3.9;HMC-1: 4.7;NB-4: 4.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007818, HPA056061" Approved Approved Nucleoplasm Nucleoplasm "CAB007818: AB_598150, HPA056061: " "unprognostic (4.79e-2)" "unprognostic (6.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-1)" "unprognostic (1.94e-2)" "unprognostic (5.09e-3)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.74e-1)" "unprognostic (8.50e-2)" "unprognostic (2.01e-2)" "unprognostic (9.07e-3)" "prognostic unfavourable (2.38e-4)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" 16.8 5.5 5.3 8.6 3.7 7.6 12.4 17.5 4.8 14.3 10.7 1.3 9.4 5.6 13.2 8.3 6.1 8.2 12.5 9.0 3.2 3.3 3.7 5.5 9.2 6.7 2.4 4.9 6.4 8.1 3.3 3.0 6.4 4.9 12.5 4.6 4.4 12.4 20.5 16.2 37.5 5.1 15.5 1.6 6.1 6.4 4.6 3.1 4.0 4.4 11.5 6.7 13.3 14.2 0.7 2.3 2.2 0.9 1.3 1.6 0.1 0.1 0.0 0.0 0.0 1.0 1.3 1.0 0.0 0.0 0.2 0.0 0.7 0.0 0.9 0.4 0.0 3.9 0.6 0.0 0.0 0.3 0.0 1.6 0.7 2.7 0.0 3.7 4.7 0.0 1.0 0.2 0.3 0.2 0.5 3.3 0.0 0.0 0.2 4.0 0.4 0.0 1.0 2.6 0.7 1.1 0.0 1.0 1.5 0.0 0.0 0.4 0.5 1.2 1.3 2.4 0.9 3.6 0.1 0.7 0.3 1.1 2.7 2.7 0.4 1.5 0.8 0.6 0.5 0.9 0.7 0.4 0.3 0.2 0.2 0.7 0.7 0.3 2.2 1.3 0.5 2.3 1.6 0.1 5.3 3.7 17.5 4.8 3.2 3.3 2.4 4.9 4.9 3.1 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019021-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 102.3" "Cell line enriched" "Detected in many" 12 "A-431: 337.7" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" 93000000 "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: , CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavourable (2.04e-5)" 16.2 8.4 4.9 7.5 6.8 0.1 39.8 5.1 8.5 13.8 7.8 3.3 10.7 3.6 8.2 11.7 15.6 8.8 8.5 4.8 6.8 2.7 7.6 23.5 14.2 2.3 4.1 3.9 10.4 10.1 1.8 2.1 102.3 5.6 10.9 6.7 9.2 15.4 12.9 10.7 32.5 6.3 15.5 3.5 3.3 7.8 5.5 5.9 3.2 12.8 15.5 8.0 10.2 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 337.7 4.3 1.1 1.5 6.9 4.3 1.1 3.3 4.5 2.0 1.6 0.8 3.7 0.2 0.8 2.8 13.5 0.0 14.9 2.5 0.1 0.2 0.0 1.8 0.2 1.8 0.0 0.0 2.1 13.7 5.2 27.9 0.2 0.0 0.0 4.4 0.2 0.0 0.0 0.3 2.2 0.0 0.6 0.0 2.5 3.6 0.0 1.3 2.8 3.4 0.6 0.3 0.7 1.0 1.9 0.5 14.6 3.1 0.0 0.3 0.1 2.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 6.8 5.1 6.6 6.8 2.7 4.1 3.9 5.6 5.9 EGLN1 "C1orf12, HIFPH2, PHD2, SM-20, ZMYND6" ENSG00000135766 "Egl-9 family hypoxia inducible factor 1" Q9GZT9 1 231363751-231425044 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Congenital erythrocytosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 14.9;skeletal muscle: 46.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 14.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 14.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022129 Approved "HPA022129: AB_1848046" "unprognostic (4.20e-1)" "prognostic unfavourable (2.99e-7)" "unprognostic (8.86e-2)" "unprognostic (1.26e-1)" "unprognostic (3.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.20e-1)" "unprognostic (3.87e-3)" "unprognostic (1.91e-1)" "unprognostic (3.99e-1)" "unprognostic (6.63e-2)" "unprognostic (9.71e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-1)" "unprognostic (1.55e-1)" "unprognostic (5.65e-2)" "unprognostic (1.81e-2)" 4.9 4.2 4.4 1.4 4.5 0.8 3.5 3.6 4.3 3.0 3.3 3.9 3.1 2.6 3.5 2.3 2.9 7.0 4.4 3.5 5.2 7.2 1.6 1.6 4.1 4.1 4.4 5.5 2.1 4.4 2.6 2.8 2.3 3.5 46.9 5.6 3.9 2.8 4.1 3.0 2.0 1.3 2.8 1.8 2.5 2.7 0.6 0.7 14.9 1.4 0.7 1.1 0.3 13.4 12.9 4.1 7.9 10.9 7.6 4.6 6.6 9.7 9.2 12.7 9.4 10.7 4.0 11.6 9.4 6.8 5.8 7.7 16.4 5.8 14.7 1.9 5.3 8.0 7.8 9.5 2.7 6.0 7.1 6.2 7.7 12.0 9.1 7.6 8.7 2.6 2.3 3.5 4.9 7.2 5.0 5.7 4.9 11.7 4.8 4.2 11.2 8.2 10.7 21.8 5.7 27.3 14.2 10.8 5.9 10.7 12.4 18.9 11.5 3.6 15.0 3.6 15.0 4.1 0.6 2.5 0.7 0.9 0.5 0.6 0.8 0.6 0.7 0.6 0.9 1.1 14.9 0.7 1.4 0.6 0.6 0.3 EGLN2 "HIFPH1, PHD1" ENSG00000269858 "Egl-9 family hypoxia inducible factor 2" Q96KS0 19 40798996-40808433 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056649 Supported Nucleoplasm Nucleoplasm "HPA056649: " "unprognostic (1.11e-2)" "prognostic favourable (2.88e-4)" "unprognostic (9.40e-3)" "unprognostic (6.01e-2)" "unprognostic (6.03e-2)" "unprognostic (6.47e-3)" "unprognostic (1.51e-2)" "unprognostic (4.74e-2)" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "prognostic favourable (4.81e-4)" "unprognostic (7.10e-2)" "unprognostic (7.48e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (9.99e-2)" "unprognostic (1.38e-3)" 27.4 24.3 24.8 24.7 28.5 23.3 33.5 22.6 28.9 22.2 21.2 21.9 26.4 17.8 24.2 17.8 16.7 18.6 23.4 18.6 25.5 18.7 18.4 19.1 31.6 29.0 21.8 25.7 22.8 16.6 10.6 16.9 42.5 16.9 20.9 15.3 16.5 19.4 25.7 15.5 13.4 16.8 28.1 15.0 42.4 18.0 74.1 18.0 14.4 29.7 17.2 22.7 19.6 25.1 25.1 16.3 68.2 21.5 15.1 30.2 26.5 16.3 44.5 20.7 20.0 26.9 19.7 13.5 17.9 15.0 25.6 28.2 36.7 16.6 14.6 15.3 21.4 10.6 26.0 20.4 13.8 18.2 14.7 19.4 26.0 13.9 28.9 14.9 26.6 24.2 21.8 24.4 14.1 31.5 27.5 13.7 26.9 11.6 27.5 24.7 17.9 15.5 25.7 10.2 9.9 27.6 25.2 19.1 17.4 29.3 23.2 23.6 30.6 40.8 29.0 32.2 23.2 13.2 21.1 6.9 10.0 25.7 23.5 21.8 23.7 20.9 19.1 46.8 24.1 21.5 25.3 23.2 28.5 24.9 16.3 25.1 30.2 25.2 68.2 15.1 19.9 11.9 25.6 26.5 24.8 28.5 22.6 28.9 25.5 18.7 21.8 25.7 16.9 18.0 EGLN3 "HIFPH3, PHD3" ENSG00000129521 "Egl-9 family hypoxia inducible factor 3" Q9H6Z9 14 33924231-34462774 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 49.6;skin 1: 44.1" "Cell line enhanced" "Detected in many" "RH-30: 17.8;RPTEC TERT1: 15.2;RT4: 47.8" "Cancer enhanced" "Detected in all" "renal cancer: 50.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 10 "plasmacytoid DC: 19.0" "Lineage enriched" "Detected in many" 16 "dendritic cells: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA064895 Supported Cytosol Cytosol "HPA064895: " "unprognostic (3.58e-2)" "unprognostic (4.76e-3)" "unprognostic (1.75e-1)" "unprognostic (8.87e-2)" "unprognostic (6.88e-2)" "unprognostic (1.38e-2)" "prognostic unfavourable (2.14e-5)" "unprognostic (1.39e-3)" "unprognostic (3.44e-2)" "unprognostic (1.79e-1)" "unprognostic (2.93e-2)" "unprognostic (2.90e-1)" "prognostic unfavourable (2.50e-4)" "unprognostic (1.37e-1)" "unprognostic (5.21e-2)" "unprognostic (4.71e-2)" "unprognostic (6.30e-2)" 6.3 0.8 12.9 4.8 10.6 0.4 6.0 3.0 11.9 7.3 14.3 13.4 4.9 19.3 5.9 2.8 10.4 5.4 7.8 49.6 10.9 7.3 6.1 2.4 3.0 3.0 10.7 8.1 2.5 6.5 0.4 1.5 19.6 9.9 9.9 11.3 3.5 4.2 11.3 9.7 44.1 21.7 11.7 9.7 2.8 19.9 1.0 12.5 3.4 1.2 1.3 5.3 25.6 16.1 0.0 19.0 1.2 0.0 0.8 1.0 0.6 11.8 3.1 0.3 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 3.2 0.0 4.0 0.0 0.3 5.9 11.5 0.0 1.2 3.1 3.2 8.7 0.4 0.0 0.0 0.1 1.6 5.8 0.0 0.0 0.0 6.3 0.0 0.1 1.0 0.2 0.0 9.6 1.1 0.0 17.8 4.2 15.2 47.8 2.5 2.8 0.8 4.6 1.2 4.7 0.0 0.0 0.1 1.3 0.0 0.6 0.1 2.5 0.0 2.9 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.8 1.9 0.0 0.1 0.0 0.1 0.8 0.0 19.0 0.0 0.6 12.9 10.6 3.0 9.8 10.9 7.3 10.7 8.1 9.9 12.5 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 37.1;liver: 91.2" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced "HPA036401: AB_10670165, HPA042021: " "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favourable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 4.1 1.2 1.2 1.7 1.4 0.1 1.5 0.5 1.2 1.7 6.4 0.8 0.4 5.2 1.0 2.0 2.9 0.8 3.0 3.2 1.2 0.9 37.1 91.2 1.9 1.0 1.7 0.7 0.8 2.5 2.7 0.9 1.3 2.1 1.7 2.6 8.3 2.7 0.4 0.7 1.1 9.9 1.0 1.4 1.7 2.4 0.9 0.9 1.4 2.1 1.7 1.2 1.8 1.0 1.5 6.0 0.2 2.2 2.7 2.7 1.1 8.2 3.5 1.0 0.0 5.2 4.5 1.1 4.0 1.2 2.6 2.9 15.1 5.2 0.0 15.7 3.9 4.0 0.0 3.3 5.5 11.0 3.7 5.8 0.9 15.2 3.4 0.7 0.1 6.3 4.3 2.6 2.4 3.8 3.8 4.3 5.0 4.3 0.1 3.4 2.1 4.4 0.0 7.0 0.3 10.8 4.7 3.1 4.5 7.8 4.5 7.2 16.6 6.8 1.8 1.7 2.6 1.3 0.3 1.2 3.7 0.3 0.5 2.6 2.8 0.2 2.2 0.0 1.6 2.1 1.0 1.5 1.1 2.4 6.0 0.2 1.6 2.7 0.1 2.7 2.0 2.4 1.4 1.1 1.2 1.4 0.5 1.2 1.2 0.9 1.7 0.7 2.1 0.9 EHMT1 "bA188C12.1, EHMT1-IT1, Eu-HMTase1, FLJ12879, FLJ40292, KIAA1876, KMT1D" ENSG00000181090 "Euchromatic histone lysine methyltransferase 1" Q9H9B1 9 137618963-137870016 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060022 Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA060022: " "unprognostic (1.18e-1)" "unprognostic (1.64e-1)" "unprognostic (1.19e-2)" "prognostic favourable (6.56e-4)" "unprognostic (1.03e-1)" "prognostic favourable (8.91e-4)" "unprognostic (5.87e-2)" "unprognostic (1.74e-2)" "unprognostic (4.18e-3)" "unprognostic (2.34e-1)" "unprognostic (2.26e-2)" "unprognostic (7.55e-3)" "unprognostic (2.01e-2)" "unprognostic (6.58e-3)" "unprognostic (4.24e-1)" "unprognostic (7.12e-3)" "unprognostic (7.75e-2)" 16.6 18.3 16.4 23.2 22.3 24.9 17.1 23.7 20.4 16.3 20.7 21.6 20.4 17.1 22.0 13.0 17.9 18.5 20.0 12.1 12.8 9.6 12.7 14.9 14.9 25.0 27.8 12.1 21.4 13.6 15.1 16.2 17.9 18.6 16.9 12.4 19.1 16.5 18.0 23.1 17.3 17.9 21.5 12.5 22.1 16.4 30.8 21.5 22.3 18.9 11.0 22.2 19.2 15.7 20.0 19.0 25.0 13.7 13.1 15.6 6.9 11.0 22.1 24.8 22.9 10.5 10.9 20.7 14.6 9.2 10.7 8.7 14.4 13.8 33.8 14.2 11.0 23.7 14.8 15.9 8.5 18.9 10.5 14.3 22.1 9.2 9.2 21.7 17.1 9.8 11.2 12.9 12.6 17.5 21.4 11.7 7.6 25.5 25.4 10.8 24.1 14.7 32.7 21.3 19.5 8.9 20.3 21.9 17.8 27.7 19.5 6.3 21.9 17.5 16.4 12.6 13.1 19.3 13.8 7.5 20.8 27.8 9.3 11.6 13.6 13.6 13.7 16.3 15.6 11.7 10.0 13.3 13.5 13.3 10.4 20.0 13.3 11.8 25.0 13.1 12.0 19.0 11.1 6.9 16.4 22.3 23.7 20.4 12.8 9.6 27.8 12.1 18.6 21.5 EHMT2 "BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a" ENSG00000204371 "Euchromatic histone lysine methyltransferase 2" Q96KQ7 6 31879759-31897687 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 10.2;NTERA-2: 15.5;U-266/84: 12.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050550, HPA060259" Supported Supported "Nucleoplasm,Nuclear speckles" "Intracellular and membrane" "Nuclear speckles" Nucleoplasm "HPA050550: , HPA060259: " "unprognostic (3.11e-2)" "unprognostic (2.72e-1)" "unprognostic (4.39e-2)" "unprognostic (1.92e-2)" "unprognostic (5.44e-2)" "unprognostic (3.51e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (3.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.89e-2)" "unprognostic (1.88e-1)" "unprognostic (9.78e-3)" "unprognostic (8.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.25e-1)" "unprognostic (9.03e-2)" 9.4 12.2 13.1 9.6 21.4 7.6 6.3 17.1 17.5 8.0 7.7 12.3 8.4 14.6 15.0 11.7 18.0 7.6 8.1 7.6 12.3 12.4 5.3 4.4 8.5 6.9 12.6 10.6 10.6 13.2 2.2 8.1 6.0 10.3 10.4 4.3 7.2 5.6 9.6 5.2 5.5 10.1 9.6 8.4 9.1 9.8 7.6 14.9 14.6 9.5 4.8 7.2 8.7 7.6 0.3 0.6 0.0 0.7 0.1 1.1 1.3 0.0 3.5 6.3 0.0 2.8 1.5 4.0 2.7 2.2 3.1 2.6 0.0 0.0 0.0 6.2 4.5 0.0 0.0 6.8 1.5 4.1 9.4 0.0 0.0 0.0 0.0 10.2 0.0 3.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 15.5 0.0 6.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.8 5.2 0.0 0.0 3.0 3.3 2.6 5.6 0.0 9.0 12.2 2.9 3.8 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.2 0.1 0.8 0.6 0.3 0.3 1.1 1.1 0.0 0.1 0.7 0.6 0.2 1.3 13.1 21.4 17.1 16.5 12.3 12.4 12.6 10.6 10.3 14.9 EIF2AK1 "HRI, KIAA1369" ENSG00000086232 "Eukaryotic translation initiation factor 2 alpha kinase 1" Q9BQI3 7 6022244-6059230 "Enzymes, Predicted intracellular proteins" "Kinase, Protein synthesis inhibitor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016496, CAB022082, HPA061675" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB022082: , HPA016496: AB_1848057, HPA061675: " "unprognostic (7.15e-3)" "unprognostic (2.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.91e-1)" "unprognostic (6.70e-2)" "unprognostic (9.69e-3)" "prognostic unfavourable (6.99e-4)" "unprognostic (2.36e-1)" "unprognostic (2.54e-1)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (1.99e-1)" "unprognostic (5.45e-2)" "unprognostic (9.02e-2)" "unprognostic (1.06e-2)" 21.0 38.2 31.7 25.4 32.7 62.8 26.9 23.9 41.1 22.8 34.5 31.0 20.8 26.5 22.6 28.6 28.4 23.4 21.5 40.0 29.9 30.0 32.0 46.3 22.1 23.3 33.3 30.3 23.0 32.4 61.9 25.4 43.9 33.4 26.4 34.9 23.4 46.4 26.3 31.6 28.9 29.9 17.8 35.6 25.4 34.7 16.3 22.6 37.1 29.0 17.4 29.6 22.4 20.1 11.7 7.5 17.4 7.4 10.4 10.6 4.8 41.1 25.9 20.8 31.6 20.0 18.0 27.4 21.2 19.4 19.0 24.1 23.7 27.8 32.2 23.3 23.3 29.1 27.0 19.3 24.5 19.9 41.5 33.2 28.2 35.7 16.4 28.2 30.3 14.5 24.4 17.9 19.3 20.1 53.1 31.2 17.8 41.1 15.4 36.0 26.1 29.3 34.0 21.9 37.8 24.1 20.1 25.9 46.6 40.8 54.5 18.1 41.0 34.6 19.2 10.9 40.7 19.2 22.4 31.7 31.6 32.8 22.0 37.2 31.6 10.6 7.4 17.4 9.5 5.9 6.4 11.7 7.4 10.6 7.5 7.7 8.6 7.7 4.1 10.4 6.5 6.6 8.8 4.8 31.7 32.7 23.9 41.1 29.9 30.0 33.3 30.3 33.4 22.6 EIF2AK2 "EIF2AK1, PKR, PPP1R83, PRKR" ENSG00000055332 "Eukaryotic translation initiation factor 2 alpha kinase 2" P19525 2 37099210-37157065 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003845, HPA019795, HPA063893" Approved Enhanced Cytosol Cytosol "CAB003845: AB_562332, HPA019795: AB_1848060, HPA063893: " "unprognostic (1.70e-2)" "unprognostic (2.26e-1)" "unprognostic (1.62e-1)" "prognostic unfavourable (3.77e-4)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.77e-3)" "unprognostic (8.42e-2)" "unprognostic (8.02e-2)" "unprognostic (4.67e-2)" "prognostic unfavourable (2.08e-4)" "unprognostic (1.19e-1)" "unprognostic (3.15e-3)" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (4.65e-2)" "unprognostic (5.32e-2)" 25.5 14.2 15.9 16.3 15.5 36.4 13.9 16.4 19.0 14.7 13.7 9.9 9.3 14.5 17.2 21.5 12.1 12.8 15.4 10.7 13.7 19.2 12.2 11.5 13.7 10.7 14.3 15.0 18.7 11.7 19.2 21.1 18.2 17.3 15.0 12.8 10.2 23.0 17.8 7.1 6.7 15.2 16.2 14.0 15.5 14.3 5.1 12.8 14.1 13.6 8.1 10.6 14.8 15.5 8.8 6.9 27.6 10.8 8.6 9.9 3.3 24.9 12.8 7.9 10.0 8.7 11.9 15.6 13.2 19.0 41.8 40.3 14.6 14.9 13.3 17.2 14.4 14.8 13.6 13.4 18.8 29.3 7.2 14.6 9.8 9.5 8.6 14.0 0.1 9.7 5.3 16.7 12.2 10.3 10.1 13.4 9.4 11.1 17.9 7.2 8.2 9.2 18.1 19.4 6.6 7.8 9.6 8.9 9.4 16.1 11.7 25.4 6.0 4.0 13.4 17.0 18.0 7.2 21.2 9.9 16.3 0.2 8.1 9.5 14.8 17.1 8.2 11.1 8.9 10.6 9.0 8.8 7.5 8.1 6.9 7.0 6.1 7.5 27.6 8.6 10.8 4.7 9.9 3.3 15.9 15.5 16.4 19.0 13.7 19.2 14.3 15.0 17.3 12.8 EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88627576 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved "CAB009204: AB_2230863, HPA015737: AB_1848062" "unprognostic (7.25e-3)" "unprognostic (5.35e-2)" "unprognostic (3.03e-3)" "unprognostic (9.32e-2)" "unprognostic (9.39e-3)" "unprognostic (3.25e-2)" "unprognostic (2.27e-2)" "unprognostic (3.46e-3)" "unprognostic (9.84e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (9.80e-2)" "unprognostic (3.60e-3)" "unprognostic (2.90e-3)" 12.7 10.3 7.2 12.3 7.6 18.6 10.7 8.8 6.6 15.8 10.7 6.1 20.9 7.3 9.6 12.4 9.5 8.9 8.5 11.1 5.7 5.5 11.5 15.9 10.4 9.3 7.9 5.0 8.8 36.7 18.5 18.4 14.4 8.3 11.4 12.6 7.3 28.0 20.9 12.7 8.9 10.8 7.0 7.5 11.1 19.0 4.6 7.3 8.7 15.7 6.3 17.3 21.5 19.2 6.6 2.6 1.5 0.7 1.6 2.4 0.6 4.8 3.2 7.1 4.6 13.0 9.1 11.3 7.0 9.0 5.0 7.4 7.2 3.5 37.3 4.2 4.7 4.4 5.1 3.9 7.3 13.1 3.3 4.0 3.3 7.4 8.1 4.9 9.5 3.4 6.3 4.6 10.0 5.3 2.3 13.4 3.8 5.4 4.6 4.0 5.2 3.7 18.1 9.8 6.7 6.2 9.2 5.5 7.5 4.1 10.7 7.0 3.9 2.9 4.2 4.3 4.6 9.7 4.3 25.2 12.6 26.4 6.1 4.5 5.7 1.1 0.7 1.5 1.7 0.6 1.9 4.7 1.7 2.4 0.9 6.6 1.5 1.1 0.2 1.6 0.2 2.6 1.4 0.6 7.2 7.6 8.8 6.6 5.7 5.5 7.9 5.0 8.3 7.3 EIF2AK4 "GCN2, KIAA1338" ENSG00000128829 "Eukaryotic translation initiation factor 2 alpha kinase 4" Q9P2K8 15 39934146-40035591 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Activation of host autophagy by virus, Adaptive immunity, Antiviral defense, Cell cycle, Growth arrest, Host-virus interaction, Immunity, Neurogenesis, Stress response, Translation regulation" "Activator, Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, tRNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 32.9" "Group enriched" "Detected in all" 4 "dendritic cells: 32.9;monocytes: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011811 Approved Approved Cytosol Cytosol "HPA011811: " "unprognostic (3.10e-1)" "unprognostic (4.78e-3)" "unprognostic (5.97e-2)" "unprognostic (7.18e-2)" "unprognostic (1.05e-2)" "unprognostic (3.32e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-2)" "unprognostic (7.27e-2)" "unprognostic (2.38e-1)" "unprognostic (1.27e-2)" "unprognostic (6.47e-2)" "unprognostic (2.31e-2)" "unprognostic (5.11e-3)" 20.7 16.5 20.2 19.4 27.3 20.2 36.0 22.4 27.3 16.8 16.3 13.6 17.1 12.2 35.7 17.9 17.8 18.1 19.4 18.2 19.5 20.5 15.4 22.7 22.5 16.6 18.6 14.2 20.1 21.5 20.3 34.7 20.5 17.6 22.0 14.6 17.9 16.7 20.3 20.4 20.7 12.2 24.3 14.6 16.1 16.4 11.5 15.1 17.7 24.1 10.6 15.9 27.0 14.4 5.0 32.9 4.2 9.3 3.8 4.5 2.4 13.8 6.6 11.9 17.9 19.6 33.0 11.3 19.5 22.4 16.0 15.8 9.5 6.0 7.3 10.2 26.5 14.8 15.9 23.6 22.4 34.8 7.9 15.7 12.3 11.4 16.8 9.4 10.9 26.0 16.2 15.2 27.5 22.3 11.6 7.0 31.5 4.6 7.8 13.0 7.3 14.9 9.5 16.5 12.1 19.9 9.4 6.2 9.6 13.9 8.5 12.1 11.9 16.3 23.6 21.4 16.2 10.7 12.6 9.7 17.4 2.3 15.0 13.0 29.8 4.2 5.8 4.0 3.6 6.7 3.1 3.5 4.0 4.1 8.4 5.0 4.5 4.2 1.7 3.8 9.3 32.9 2.7 2.4 20.2 27.3 22.4 27.3 19.5 20.5 18.6 14.2 17.6 15.1 EIF3F "eIF3-epsilon, eIF3-p47, eIF3f, EIF3S5" ENSG00000175390 "Eukaryotic translation initiation factor 3 subunit F" O00303 11 7970251-8001862 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis, Ubl conjugation pathway" "Hydrolase, Initiation factor, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049250 Approved 18000 "HPA049250: " "unprognostic (1.11e-2)" "unprognostic (1.42e-1)" "unprognostic (8.46e-2)" "unprognostic (1.15e-2)" "unprognostic (8.50e-2)" "unprognostic (2.26e-1)" "prognostic unfavourable (6.86e-4)" "unprognostic (1.16e-1)" "unprognostic (1.97e-1)" "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.04e-1)" "unprognostic (1.57e-1)" "unprognostic (5.66e-2)" "unprognostic (2.61e-1)" "unprognostic (8.36e-2)" "unprognostic (8.78e-2)" 38.2 28.5 19.8 40.4 22.0 36.6 50.8 16.4 22.7 44.4 41.4 23.2 35.0 25.4 40.6 35.7 45.8 41.1 42.6 38.6 17.0 14.7 29.7 32.2 33.9 82.2 19.9 20.4 74.6 67.4 23.0 23.5 28.9 17.8 45.0 31.2 26.2 49.2 29.7 71.4 56.8 31.7 54.2 20.1 37.1 40.9 42.5 20.0 88.5 50.8 47.7 51.6 48.0 55.5 60.4 48.1 14.7 35.6 34.7 65.7 70.3 29.8 19.2 31.0 23.0 39.8 74.2 28.8 23.9 35.1 26.2 26.2 20.0 41.5 52.8 12.6 29.3 21.7 20.9 45.2 33.2 15.5 39.2 22.9 23.0 29.7 68.2 29.3 23.0 59.3 44.1 14.8 49.0 32.5 18.6 22.4 32.8 20.1 34.2 39.3 28.1 28.7 43.4 17.7 20.4 26.3 30.9 20.6 42.9 13.5 23.5 25.3 19.7 22.3 24.6 18.4 27.9 12.3 17.6 20.7 27.2 26.1 19.4 14.4 24.6 14.0 35.2 14.7 31.9 35.6 44.7 60.4 54.6 39.8 48.1 53.7 65.7 48.3 5.4 34.7 32.9 34.6 60.5 70.3 19.8 22.0 16.4 22.7 17.0 14.7 19.9 20.4 17.8 20.0 EIF4A1 "DDX2A, EIF-4A, EIF4A" ENSG00000161960 "Eukaryotic translation initiation factor 4A1" P60842 17 7572706-7579005 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011689, HPA068286" Uncertain Approved Cytosol 2300000 Cytosol "CAB011689: AB_732122, HPA068286: " "unprognostic (1.49e-2)" "unprognostic (2.41e-1)" "unprognostic (8.00e-2)" "unprognostic (2.17e-1)" "unprognostic (2.49e-1)" "unprognostic (2.12e-3)" "unprognostic (7.25e-2)" "unprognostic (2.89e-2)" "unprognostic (2.72e-2)" "unprognostic (2.11e-2)" "unprognostic (2.65e-2)" "unprognostic (5.19e-3)" "prognostic unfavourable (1.76e-8)" "unprognostic (1.91e-1)" "unprognostic (5.96e-2)" "unprognostic (1.16e-1)" "unprognostic (1.13e-2)" 56.5 49.0 19.3 41.4 19.8 51.4 80.2 13.6 26.6 40.4 45.6 28.5 26.4 28.7 45.9 30.2 76.4 43.4 39.2 33.5 18.5 17.1 34.2 58.0 46.3 135.7 27.7 12.9 55.2 77.0 19.8 28.8 45.2 21.8 36.2 44.0 33.0 65.8 30.7 36.5 48.4 30.9 46.5 33.4 46.8 42.2 31.6 21.8 91.5 34.7 73.8 67.7 42.5 40.8 35.1 143.6 29.1 115.7 47.1 60.3 170.1 84.2 115.6 77.5 70.2 69.7 81.7 72.4 81.4 92.6 150.9 116.7 116.6 38.2 115.4 62.7 85.3 75.7 164.4 125.3 162.7 37.3 121.9 65.0 75.2 129.6 106.9 66.4 65.8 108.2 64.8 126.8 129.7 113.2 66.3 23.9 108.6 88.6 68.9 57.0 66.4 80.1 65.1 58.5 55.4 105.5 77.5 41.0 79.6 73.3 49.4 102.0 54.8 51.1 80.9 79.8 55.7 51.0 163.6 23.5 32.8 75.6 85.8 81.8 87.4 19.6 115.7 29.1 37.0 102.6 60.3 35.1 40.0 39.5 143.6 28.9 39.4 39.6 12.1 47.1 75.7 54.8 49.2 170.1 19.3 19.8 13.6 26.6 18.5 17.1 27.7 12.9 21.8 21.8 EIF4A2 "BM-010, DDX2B, EIF4A, EIF4F" ENSG00000156976 "Eukaryotic translation initiation factor 4A2" Q14240 3 186783205-186789900 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB011690, HPA068286" Uncertain Approved Cytosol 1000000 Cytosol "CAB011690: AB_732123, HPA068286: " "unprognostic (1.49e-1)" "unprognostic (9.62e-2)" "unprognostic (3.78e-2)" "unprognostic (9.50e-3)" "unprognostic (2.82e-2)" "unprognostic (1.10e-2)" "unprognostic (4.46e-2)" "unprognostic (6.27e-2)" "unprognostic (4.32e-3)" "unprognostic (1.00e-1)" "unprognostic (6.39e-2)" "unprognostic (3.99e-2)" "unprognostic (6.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.03e-1)" "unprognostic (4.67e-2)" "unprognostic (2.62e-2)" 34.6 66.1 61.2 27.7 79.9 1.9 53.5 121.1 111.5 65.1 52.1 26.5 30.1 30.3 73.1 45.5 44.5 73.9 45.1 83.7 58.4 71.9 63.9 43.5 33.7 36.1 48.9 61.7 142.0 59.0 30.9 84.1 47.3 69.6 57.9 40.1 31.8 43.7 62.8 126.7 19.8 35.6 57.1 41.9 32.5 39.0 32.9 39.5 23.9 67.8 36.4 35.4 61.1 51.7 55.1 19.3 39.4 24.8 33.0 63.4 51.3 10.5 5.3 22.3 3.6 85.9 81.0 6.8 19.0 17.2 20.2 26.6 19.6 3.8 23.6 106.5 27.3 17.8 32.7 8.0 35.6 22.0 17.2 38.0 7.1 26.3 33.7 8.0 26.7 54.2 38.5 5.8 48.6 35.8 12.8 39.8 65.6 1.8 12.7 3.9 22.1 25.5 16.3 15.8 14.3 40.0 12.9 43.9 8.8 30.9 21.3 40.4 33.2 29.3 26.1 16.0 8.0 15.4 11.6 31.7 44.8 10.8 11.0 8.4 7.5 39.4 16.0 18.5 28.5 18.2 45.3 55.1 41.9 34.8 19.3 46.1 63.4 50.2 11.0 33.0 24.8 17.4 38.6 51.3 61.2 79.9 121.1 111.5 58.4 71.9 48.9 61.7 69.6 39.5 EIF4A3 "DDX48, EIF4AIII, Fal1, KIAA0111" ENSG00000141543 "Eukaryotic translation initiation factor 4A3" P38919 17 80135214-80147183 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, rRNA processing, Translation regulation, Transport" "Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021878 Supported Supported Nucleoplasm 73000 Nucleoplasm "HPA021878: AB_1848090" "unprognostic (7.24e-2)" "unprognostic (7.33e-3)" "prognostic favourable (3.57e-5)" "unprognostic (1.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.52e-2)" "prognostic unfavourable (1.68e-5)" "prognostic unfavourable (1.87e-4)" "unprognostic (3.71e-1)" "unprognostic (5.06e-2)" "unprognostic (4.64e-2)" "unprognostic (2.64e-2)" "unprognostic (9.78e-3)" "unprognostic (5.81e-2)" "unprognostic (9.20e-2)" "unprognostic (1.38e-2)" "unprognostic (2.91e-3)" 27.3 37.0 19.6 23.6 21.5 71.7 22.0 20.3 19.8 24.2 23.8 16.9 19.2 16.2 24.9 18.0 41.5 29.4 17.1 24.2 17.8 12.3 24.5 20.3 21.6 25.4 16.8 19.7 37.5 16.8 17.1 21.9 38.3 13.1 24.7 20.9 14.7 22.1 31.2 19.8 31.2 18.6 18.5 13.7 25.5 20.4 35.1 19.3 30.7 26.9 26.4 30.6 28.9 25.8 38.7 80.4 33.1 41.9 30.2 38.9 48.3 47.5 42.7 28.2 20.9 21.7 13.3 24.7 25.3 18.0 35.9 28.9 45.5 22.3 43.6 17.0 22.1 31.8 38.7 27.0 40.0 16.1 40.5 27.3 33.8 49.0 21.4 49.1 28.6 20.3 13.9 30.0 24.4 29.3 36.3 28.3 21.2 36.4 44.3 25.0 30.3 39.6 36.7 57.2 34.4 17.5 40.8 39.4 21.5 34.8 68.1 29.2 44.5 33.1 20.1 22.3 28.6 32.8 39.8 24.8 21.4 80.5 18.0 31.1 22.8 25.7 41.1 33.1 26.7 41.9 34.5 38.7 34.5 30.8 50.3 31.6 32.0 30.7 24.4 30.2 32.9 80.4 38.9 48.3 19.6 21.5 20.3 19.8 17.8 12.3 16.8 19.7 13.1 19.3 EIF5B "DKFZp434I036, FLJ10524, IF2, KIAA0741" ENSG00000158417 "Eukaryotic translation initiation factor 5B" O60841 2 99337353-99401326 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034648, HPA040095" Approved Approved "Plasma membrane,Cytosol" 11000 Cytosol "Plasma membrane" "HPA034648: AB_10601902, HPA040095: " "unprognostic (1.23e-1)" "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (5.03e-2)" "unprognostic (4.65e-2)" "unprognostic (5.88e-3)" "prognostic unfavourable (7.15e-10)" "unprognostic (6.80e-2)" "unprognostic (9.84e-3)" "prognostic favourable (8.99e-4)" "unprognostic (1.68e-2)" "unprognostic (2.36e-1)" "prognostic unfavourable (1.42e-6)" "unprognostic (6.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.43e-1)" "unprognostic (7.93e-3)" 24.5 16.0 25.2 22.4 32.6 11.5 22.6 27.7 26.0 23.7 25.1 10.5 19.9 14.8 19.4 28.7 30.8 14.5 15.0 61.7 26.0 22.3 28.8 32.1 17.9 19.2 26.9 23.0 22.3 24.6 26.8 27.5 26.4 28.5 26.0 20.3 7.1 22.3 29.1 105.8 25.3 19.3 31.5 37.6 27.0 20.7 22.6 33.8 17.8 18.2 29.2 22.8 40.1 31.9 15.9 20.2 11.6 12.1 14.1 14.9 4.5 33.7 16.9 19.3 25.1 23.4 27.8 32.0 29.8 18.8 19.9 19.8 38.9 24.2 38.7 25.9 22.2 19.4 33.7 28.9 35.2 23.4 20.2 46.5 17.3 51.1 18.6 45.5 28.8 18.7 20.4 27.6 28.3 28.9 51.3 19.4 28.5 27.4 28.8 42.2 30.1 24.9 25.2 28.7 31.6 40.7 28.4 16.4 15.5 16.2 37.4 24.0 15.2 30.1 31.7 30.9 30.3 16.1 26.5 14.4 20.4 31.6 22.5 50.5 22.7 11.6 8.8 9.8 12.7 9.5 14.9 15.3 13.4 12.5 6.4 15.9 13.2 14.0 2.3 14.1 12.1 20.2 9.0 4.5 25.2 32.6 27.7 26.0 26.0 22.3 26.9 23.0 28.5 33.8 ELAC1 D29 ENSG00000141642 "ElaC ribonuclease Z 1" Q9H777 18 50967991-50988121 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040867, HPA066483" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA040867: AB_10697716, HPA066483: " "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "unprognostic (6.95e-3)" "unprognostic (1.75e-2)" "unprognostic (8.61e-2)" "unprognostic (5.96e-2)" "unprognostic (3.25e-1)" "unprognostic (3.03e-3)" "unprognostic (5.87e-2)" "unprognostic (2.82e-3)" "unprognostic (3.67e-3)" "unprognostic (6.36e-2)" "prognostic favourable (8.43e-8)" "unprognostic (3.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (3.87e-2)" 8.7 15.0 7.7 7.7 9.7 3.3 9.4 7.1 11.9 8.0 9.1 12.8 12.1 7.6 11.3 20.1 7.5 10.0 9.6 7.2 7.3 8.3 12.4 15.2 7.6 11.2 7.6 7.2 8.8 19.5 17.1 15.7 12.3 8.7 9.9 10.8 13.7 20.1 12.2 6.8 7.7 11.7 8.3 7.1 10.8 10.1 16.7 3.9 10.1 15.6 7.0 9.9 8.7 6.6 14.2 12.4 7.8 9.1 16.1 15.7 8.1 6.9 4.8 12.7 10.8 14.3 6.1 5.4 7.6 10.1 7.2 5.1 1.8 6.6 5.4 5.3 7.0 7.0 3.9 8.0 4.9 11.7 1.0 6.6 1.8 1.2 8.4 16.7 4.8 7.6 6.4 3.8 8.9 7.4 6.7 13.5 12.6 3.1 5.7 5.0 6.3 2.1 6.6 4.5 10.0 8.3 3.0 7.5 8.6 6.3 1.1 12.1 5.9 12.8 6.5 9.4 4.9 2.7 5.1 12.7 10.6 7.2 8.7 5.6 11.8 4.1 7.8 7.8 13.2 9.1 14.6 14.2 12.7 12.9 12.4 13.6 12.4 15.7 0.9 16.1 8.7 10.4 10.0 8.1 7.7 9.7 7.1 11.9 7.3 8.3 7.6 7.2 8.7 3.9 ELAC2 "FLJ10530, HPC2" ENSG00000006744 "ElaC ribonuclease Z 2" Q9BQ52 17 12992391-13018187 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Disease mutation, Primary mitochondrial disease, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019535 Approved Enhanced Nucleoplasm Nucleoplasm "HPA019535: AB_1848106" "unprognostic (4.24e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "prognostic favourable (3.24e-6)" "unprognostic (8.64e-2)" "unprognostic (1.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.47e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-1)" "unprognostic (5.31e-3)" "unprognostic (3.09e-1)" "unprognostic (5.31e-3)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (8.09e-2)" "unprognostic (3.70e-2)" 20.3 35.9 15.2 17.2 23.5 13.8 18.6 16.9 30.0 17.5 21.2 24.6 17.9 15.8 22.1 13.1 25.9 19.5 19.6 28.1 14.2 14.3 23.5 34.8 14.2 19.4 18.2 19.5 20.3 24.5 27.5 14.0 21.2 20.5 20.7 25.1 19.4 19.1 26.2 49.2 20.7 18.7 26.6 15.6 25.5 22.8 29.5 17.1 28.1 20.7 20.1 25.9 23.0 16.3 19.9 23.5 9.4 20.4 24.0 25.1 20.9 20.2 32.2 22.4 24.9 17.9 17.5 13.6 22.2 17.9 36.3 24.4 25.9 10.8 36.7 24.2 21.1 27.4 40.5 25.7 36.3 19.0 40.8 21.4 25.2 17.0 13.3 18.3 29.7 15.6 21.9 28.2 26.3 25.4 29.3 11.2 27.5 18.0 32.3 18.3 18.5 21.6 22.7 38.2 23.0 20.5 18.2 11.5 16.8 28.2 18.4 11.4 18.3 8.0 24.7 44.9 14.9 17.7 32.6 7.0 13.0 14.8 17.8 19.6 16.3 9.4 14.7 9.3 21.4 20.1 23.0 19.9 20.7 21.3 23.5 17.4 21.5 19.2 2.2 24.0 20.4 13.3 25.1 20.9 15.2 23.5 16.9 30.0 14.2 14.3 18.2 19.5 20.5 17.1 ELANE "ELA2, HLE, HNE, NE" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 244.3" "Cell line enriched" "Detected in some" 65 "THP-1: 193.2" "Group enriched" "Detected in some" 7 "pancreatic cancer: 3.5;stomach cancer: 3.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 3.2;neutrophil: 6.9" "Group enriched" "Detected in many" 9 "granulocytes: 6.9;monocytes: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB015409, HPA066836" Enhanced "Secreted to blood" 59000 "CAB015409: AB_831596, HPA066836: " "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.43e-2)" "unprognostic (3.92e-1)" "unprognostic (6.38e-3)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (3.48e-2)" "unprognostic (1.19e-10)" "unprognostic (6.27e-3)" "unprognostic (4.00e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-3)" 1.5 0.3 0.1 0.3 0.1 244.3 1.6 0.2 0.6 0.3 0.6 0.7 0.0 0.3 0.3 0.7 0.5 0.6 0.8 31.2 0.0 0.0 0.3 1.5 17.8 1.6 0.0 0.0 0.3 1.8 0.3 0.4 4.7 0.5 1.4 0.3 1.0 0.7 0.3 1.1 2.1 0.5 0.5 0.0 22.5 0.5 0.3 0.0 23.0 2.3 0.9 0.3 1.0 0.2 0.0 0.0 6.9 3.2 0.0 0.5 11.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 193.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.2 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 11.2 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.5 0.0 ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363397-43368074 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 101.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: " "unprognostic (5.23e-2)" "prognostic unfavourable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavourable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavourable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" 21.2 15.6 16.2 15.3 25.3 18.3 24.1 6.8 32.5 16.1 23.6 101.5 11.7 20.7 14.1 13.0 46.6 15.1 17.3 11.5 30.3 18.3 26.6 23.8 22.9 22.7 51.4 14.1 9.3 18.3 16.7 8.4 20.9 45.6 21.6 20.1 8.6 20.6 21.6 6.8 54.0 21.7 20.7 99.5 17.2 22.8 8.4 37.2 7.2 23.9 15.6 21.7 20.4 22.6 30.9 61.1 46.9 54.8 30.5 32.3 48.8 23.5 26.6 5.2 10.2 35.2 33.1 16.1 27.9 35.3 35.7 28.8 23.6 41.5 16.3 21.8 43.8 27.2 18.2 34.4 21.9 20.9 12.3 21.2 18.4 17.0 30.6 18.2 22.6 25.3 39.2 42.2 46.6 35.6 14.6 12.4 40.8 17.4 4.2 15.3 7.6 27.5 9.6 13.7 19.9 45.0 28.8 6.3 6.6 16.5 59.1 23.6 27.7 18.2 29.5 30.3 19.1 36.6 35.4 6.2 6.7 7.8 29.4 18.7 27.2 29.0 54.8 46.9 32.3 50.6 28.6 30.9 30.7 31.4 61.1 25.5 20.1 28.1 38.2 30.5 48.1 42.9 31.4 48.8 16.2 25.3 6.8 32.5 30.3 18.3 51.4 14.1 45.6 37.2 ELOVL3 CIG-30 ENSG00000119915 "ELOVL fatty acid elongase 3" Q9HB03 10 102226328-102229589 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 24.6" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 8.1;HSkMC: 11.9;NB-4: 9.2;SiHa: 18.5" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 11 "classical monocyte: 9.4;intermediate monocyte: 3.1;myeloid DC: 2.6;non-classical monocyte: 6.6" "Group enriched" "Detected in many" 12 "dendritic cells: 2.6;monocytes: 9.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036236 Enhanced Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA036236: AB_10601550" "unprognostic (1.52e-2)" "unprognostic (6.76e-2)" "unprognostic (1.84e-2)" "prognostic unfavourable (6.25e-5)" "unprognostic (8.23e-3)" "unprognostic (9.82e-2)" "unprognostic (2.17e-4)" "unprognostic (4.27e-2)" "unprognostic (2.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (5.36e-3)" "unprognostic (2.66e-9)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" 6.3 1.1 1.2 2.1 2.4 3.6 7.3 0.4 0.9 0.2 0.2 0.0 0.0 0.0 0.9 0.3 0.3 0.3 2.5 2.5 0.6 0.2 0.5 0.2 1.8 0.1 0.7 0.0 0.2 0.2 0.0 1.8 2.4 1.1 0.3 0.2 1.6 3.4 1.7 1.7 24.6 0.3 0.0 0.2 0.8 0.2 6.8 0.0 0.0 0.2 2.8 0.0 0.6 2.6 0.0 2.6 0.5 9.4 0.0 0.0 1.9 2.6 0.2 0.1 6.5 8.2 8.1 2.3 0.1 0.2 0.3 0.4 0.4 2.5 0.0 0.3 0.0 0.0 4.9 0.0 0.4 0.0 0.0 0.1 0.3 0.6 0.3 0.0 0.1 11.9 1.4 3.0 0.0 0.0 0.1 2.9 0.7 0.0 0.0 9.2 0.1 0.9 0.0 4.3 0.0 1.6 0.0 0.0 0.3 18.5 0.8 0.6 6.7 2.2 0.0 1.3 0.0 0.3 0.2 0.4 5.7 0.0 2.9 5.3 0.0 0.0 9.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.5 0.0 6.6 0.0 0.0 1.9 1.2 2.4 0.4 0.9 0.6 0.2 0.7 0.0 1.1 0.0 ELOVL5 "dJ483K16.1, HELO1, SCA38" ENSG00000012660 "ELOVL fatty acid elongase 5" Q9NYP7 6 53267398-53349179 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017042, HPA047752, HPA054197" Enhanced Enhanced "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB017042: , HPA047752: , HPA054197: " "unprognostic (7.33e-2)" "unprognostic (5.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (3.06e-1)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.43e-2)" "unprognostic (3.23e-1)" "unprognostic (6.40e-2)" "prognostic unfavourable (1.94e-6)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "prognostic unfavourable (6.80e-4)" "unprognostic (2.76e-2)" 75.7 48.7 17.9 24.2 22.0 33.9 78.8 13.3 22.1 18.2 13.9 38.3 91.2 9.7 15.7 18.0 10.8 16.5 18.0 14.6 18.3 17.5 13.5 36.8 24.4 33.6 41.1 12.3 13.1 5.7 8.1 11.6 13.6 26.4 45.2 6.7 16.1 9.4 88.4 3.6 11.4 17.3 18.0 46.4 18.5 9.5 34.8 29.1 28.7 17.6 5.6 33.6 16.6 19.4 23.8 18.1 60.7 11.3 8.4 25.3 10.4 25.5 18.7 32.8 59.9 87.1 50.6 14.0 29.9 33.6 24.2 34.0 16.5 29.7 29.1 21.7 31.0 15.2 32.3 27.3 36.3 24.5 22.7 28.7 17.4 23.0 47.9 22.6 21.0 46.7 21.5 24.2 30.4 26.8 35.8 16.9 17.4 2.8 67.2 20.1 17.7 14.3 26.2 22.5 10.1 45.5 15.3 30.6 21.1 24.7 12.9 25.0 29.5 21.2 25.4 26.6 23.6 47.3 39.3 14.3 13.1 22.1 13.8 33.0 18.8 9.0 11.3 40.7 8.8 8.1 14.2 21.6 14.7 10.6 18.1 23.8 7.2 6.7 60.7 8.4 9.6 4.8 25.3 10.4 17.9 22.0 13.3 20.2 18.3 17.5 41.1 12.3 26.4 29.1 ELOVL6 "FLJ23378, LCE, MGC5487" ENSG00000170522 "ELOVL fatty acid elongase 6" Q9H5J4 4 110045846-110199199 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 43.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 4.8;MAIT T-cell: 4.9;memory CD4 T-cell: 2.1;memory CD8 T-cell: 3.2;naive CD8 T-cell: 2.3;NK-cell: 5.6" "Group enriched" "Detected in many" 20 "NK-cells: 5.6;T-cells: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042355 Uncertain "HPA042355: AB_10796577" "unprognostic (3.92e-2)" "unprognostic (9.47e-2)" "prognostic favourable (6.74e-4)" "unprognostic (8.09e-2)" "unprognostic (2.06e-2)" "unprognostic (1.08e-3)" "unprognostic (4.16e-1)" "unprognostic (3.01e-3)" "unprognostic (4.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.33e-1)" "unprognostic (1.90e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (5.32e-2)" 7.6 9.8 7.7 7.9 9.4 3.7 7.9 10.9 12.3 4.0 14.5 8.6 0.9 11.8 3.4 2.7 16.6 2.9 11.1 8.1 6.6 5.9 6.4 43.9 3.3 2.2 7.5 9.4 2.0 2.5 10.6 7.1 2.6 15.7 3.0 14.1 4.3 6.9 3.2 1.4 12.3 10.2 5.7 20.0 1.9 16.9 1.3 7.3 1.1 2.3 7.9 4.0 6.0 5.0 0.1 0.0 0.2 0.1 5.6 4.9 0.8 13.2 7.8 28.8 7.1 19.3 20.3 14.7 9.2 4.5 3.2 7.3 3.8 23.3 1.0 0.8 7.1 12.4 21.8 27.0 7.5 4.5 6.3 15.0 8.5 10.0 12.0 14.5 9.7 17.7 6.2 16.5 7.9 6.4 17.8 30.9 7.2 6.9 3.3 1.5 13.2 4.8 2.2 11.3 3.8 21.0 9.9 5.1 11.0 4.7 31.4 4.0 5.3 0.1 2.3 6.5 7.8 11.0 11.1 1.4 4.8 24.4 10.0 0.0 1.6 0.2 0.1 0.1 4.8 0.0 4.9 0.1 2.1 3.2 0.0 0.1 0.7 2.3 0.2 5.6 0.0 0.0 0.2 0.8 7.7 9.4 10.9 12.3 6.6 5.9 7.5 9.4 15.7 7.3 ELOVL7 FLJ23563 ENSG00000164181 "ELOVL fatty acid elongase 7" A1L3X0 5 60751791-60844389 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.8;neutrophil: 2.9" "Lineage enriched" "Detected in single" 15 "granulocytes: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036337 Approved "HPA036337: AB_10670797" "unprognostic (6.34e-2)" "unprognostic (1.96e-2)" "unprognostic (1.51e-2)" "prognostic unfavourable (3.87e-5)" "unprognostic (3.84e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "prognostic favourable (1.54e-9)" "unprognostic (6.95e-2)" "unprognostic (1.01e-3)" "unprognostic (2.94e-1)" "unprognostic (6.30e-3)" 9.9 5.3 11.4 2.1 15.2 1.1 21.4 7.5 12.4 4.0 7.9 15.0 1.4 10.5 2.8 2.1 5.0 2.4 17.5 1.1 13.8 10.9 15.0 1.2 3.7 2.3 19.0 7.7 0.8 7.6 17.2 3.3 3.1 16.7 20.4 10.8 4.2 3.9 1.5 0.9 23.0 18.9 3.6 26.2 0.9 2.9 1.0 11.7 0.0 15.4 5.0 3.7 5.7 5.0 0.1 0.1 3.8 0.2 0.1 0.1 5.8 11.5 4.3 0.0 0.3 0.0 0.0 10.9 0.0 2.5 1.5 5.1 5.6 12.4 0.0 5.3 0.0 0.6 7.4 4.7 2.2 16.0 3.8 21.0 0.5 1.8 0.1 1.7 9.0 0.1 8.6 0.1 7.5 0.0 3.2 4.2 0.0 10.1 0.1 0.1 1.4 0.0 0.9 1.2 0.7 11.5 11.2 4.7 0.7 6.4 5.1 2.8 8.5 0.3 0.1 1.0 5.3 0.1 4.0 11.0 10.9 0.1 7.8 0.4 0.2 3.8 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 2.9 0.1 0.1 0.1 0.0 5.8 11.4 15.2 7.5 12.4 13.8 10.9 19.0 7.7 16.7 11.7 ELP3 "FLJ10422, KAT9" ENSG00000134014 "Elongator acetyltransferase complex subunit 3" Q9H9T3 8 28089673-28191156 "Enzymes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation, tRNA processing" "Acyltransferase, RNA-binding, Transferase, tRNA-binding" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025297, HPA025812" Uncertain Supported Cytosol Cytosol "HPA025297: , HPA025812: AB_10601369" "unprognostic (1.29e-2)" "unprognostic (1.26e-2)" "prognostic favourable (9.25e-4)" "unprognostic (3.49e-3)" "unprognostic (5.73e-2)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.07e-2)" "unprognostic (7.66e-2)" "unprognostic (1.22e-2)" "unprognostic (3.89e-1)" "unprognostic (3.46e-2)" "prognostic favourable (1.31e-5)" "unprognostic (2.29e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" 14.8 15.3 18.7 11.5 23.4 6.7 19.4 20.0 27.4 33.4 14.8 21.8 35.2 10.8 27.3 14.4 12.8 18.6 17.5 16.0 17.7 19.0 19.1 22.8 13.6 15.4 17.6 13.6 18.9 12.6 14.3 17.4 12.7 23.3 15.9 18.0 13.9 11.1 36.1 28.8 13.4 12.3 16.0 15.8 16.1 12.1 15.0 15.5 16.0 19.9 13.8 20.3 14.7 12.0 16.2 12.2 11.6 18.2 15.8 20.8 11.0 14.3 15.1 11.5 11.0 17.0 14.9 8.2 7.4 13.4 17.4 15.6 12.5 6.1 27.1 11.7 14.2 9.8 12.6 17.6 20.6 4.9 5.2 18.2 10.0 20.6 15.2 9.8 13.6 15.7 27.2 12.0 18.5 16.3 20.4 16.8 17.8 8.8 20.8 16.7 12.9 5.3 15.8 11.2 10.4 17.4 11.8 6.9 12.0 8.4 7.2 14.1 13.7 11.3 11.4 12.0 15.7 12.4 10.7 7.1 11.4 20.8 11.9 11.0 12.2 11.6 10.1 8.2 19.4 14.4 20.8 12.5 16.6 18.3 11.8 16.2 15.0 17.0 2.8 15.8 18.2 12.2 15.6 11.0 18.7 23.4 20.0 27.4 17.7 19.0 17.6 13.6 23.3 15.5 ENGASE FLJ21865 ENSG00000167280 Endo-beta-N-acetylglucosaminidase Q8NFI3 17 79074939-79088599 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 51.4" "Cell line enhanced" "Detected in many" "SK-BR-3: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021551 Approved Approved Centrosome,Cytosol "Centrosome, Cytosol" "HPA021551: AB_1848156" "unprognostic (7.49e-2)" "unprognostic (1.42e-1)" "unprognostic (5.65e-2)" "unprognostic (6.16e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-3)" "unprognostic (9.62e-2)" "unprognostic (4.09e-2)" "unprognostic (9.07e-2)" "unprognostic (7.00e-3)" "prognostic favourable (2.60e-4)" "unprognostic (4.79e-2)" "prognostic unfavourable (8.97e-6)" "unprognostic (8.38e-3)" "unprognostic (6.03e-1)" "unprognostic (2.06e-2)" "prognostic favourable (8.73e-5)" 10.0 10.1 9.5 20.7 18.4 8.9 11.4 7.0 13.9 10.9 15.1 12.4 8.8 20.3 11.4 6.8 6.5 10.6 8.6 10.3 9.3 5.8 9.2 10.2 10.1 10.7 16.8 8.5 16.3 9.3 11.3 9.8 8.1 13.6 12.3 12.5 10.7 12.1 9.6 35.4 11.9 17.3 7.3 11.9 24.9 11.4 3.9 14.0 8.1 13.6 7.0 9.1 17.5 51.4 0.2 0.7 0.0 1.1 0.0 2.1 0.6 4.5 9.6 3.4 6.2 3.6 1.5 6.5 3.4 1.7 2.8 2.0 5.1 4.9 0.0 4.2 3.5 6.7 5.4 3.7 1.6 2.7 7.2 4.0 9.8 3.0 2.7 4.6 7.7 4.0 5.2 2.4 2.7 2.9 5.8 2.8 1.8 3.8 0.4 4.4 1.5 8.7 8.5 11.6 2.9 1.5 12.7 2.8 5.7 5.5 25.5 2.5 9.0 4.4 3.8 5.5 4.1 4.8 3.4 6.8 1.2 1.9 2.3 8.5 4.0 0.0 0.7 0.0 0.0 1.1 0.9 0.0 0.1 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.5 0.6 2.1 0.6 9.5 18.4 7.0 13.9 9.3 5.8 16.8 8.5 13.6 14.0 ENO1 "ENO1L1, MBP-1, MPB1, PPH" ENSG00000074800 "Enolase 1" P06733 1 8861000-8879250 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Plasminogen activation, Transcription, Transcription regulation" "DNA-binding, Lyase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018614, HPA068284, HPA068721, CAB069394" Supported Enhanced "Plasma membrane,Cytosol" 490000000 "Plasma membrane, Cytosol" "CAB018614: AB_2099061, CAB069394: , HPA068284: , HPA068721: " "unprognostic (6.51e-3)" "unprognostic (9.50e-3)" "unprognostic (3.56e-2)" "unprognostic (1.86e-1)" "prognostic unfavourable (2.71e-4)" "unprognostic (1.82e-2)" "prognostic unfavourable (1.30e-8)" "unprognostic (2.37e-2)" "unprognostic (5.58e-2)" "unprognostic (9.72e-2)" "unprognostic (1.67e-2)" "unprognostic (1.46e-1)" "unprognostic (7.53e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.36e-3)" 68.6 57.7 92.7 94.9 109.6 121.8 73.4 46.6 119.4 47.3 63.8 74.6 21.7 71.3 44.9 24.2 138.2 52.2 55.0 45.2 79.1 70.7 180.4 165.4 64.8 80.3 74.9 62.7 58.2 31.6 52.7 35.5 70.5 88.6 38.6 66.4 62.6 106.1 69.1 45.0 74.6 70.3 84.0 56.4 80.0 44.3 31.7 48.8 98.8 55.4 91.0 119.3 73.5 62.9 38.7 114.1 22.1 105.4 55.5 63.7 159.3 180.7 158.0 76.2 65.2 63.8 71.3 69.1 98.3 109.0 211.8 199.1 101.1 105.0 130.3 131.2 118.2 89.2 129.4 262.3 216.0 88.9 136.7 110.0 160.5 125.6 95.9 219.2 67.8 73.6 79.6 167.7 255.0 135.6 120.5 51.0 137.3 89.5 82.6 117.4 83.1 158.6 85.6 113.6 212.8 250.7 43.1 103.1 63.7 115.3 167.9 121.2 84.1 65.7 123.9 146.7 129.9 125.1 167.1 145.5 103.2 197.7 227.8 179.8 123.1 13.9 105.4 20.8 52.3 75.8 59.1 38.7 55.8 53.8 114.1 32.7 45.6 47.8 22.1 55.5 72.4 31.2 63.7 159.3 92.7 109.6 46.6 119.4 79.1 70.7 74.9 62.7 88.6 48.8 ENO2 ENSG00000111674 "Enolase 2" P09104 12 6913745-6923698 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 119.2" "Cell line enhanced" "Detected in many" "U-87 MG: 81.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 8.2;MAIT T-cell: 9.7;memory B-cell: 5.6;memory CD4 T-cell: 10.8;memory CD8 T-cell: 9.6;naive B-cell: 3.3;naive CD4 T-cell: 7.1;naive CD8 T-cell: 7.4;neutrophil: 6.2;T-reg: 5.5" "Group enriched" "Detected in many" 7 "B-cells: 5.6;granulocytes: 6.2;T-cells: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000063, HPA068284, HPA068721, CAB073539, CAB079023" Enhanced Supported Supported "Plasma membrane,Cytosol" 89000000 "Plasma membrane, Cytosol" "CAB000063: AB_2099322, CAB073539: , CAB079023: , HPA068284: , HPA068721: " "unprognostic (8.96e-2)" "unprognostic (8.28e-2)" "prognostic unfavourable (6.96e-4)" "unprognostic (1.28e-1)" "unprognostic (7.95e-3)" "unprognostic (1.39e-2)" "prognostic unfavourable (5.15e-4)" "unprognostic (1.48e-1)" "unprognostic (9.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "prognostic unfavourable (7.89e-11)" "unprognostic (7.61e-2)" "unprognostic (3.06e-1)" "unprognostic (8.10e-3)" "unprognostic (1.24e-1)" 4.2 20.7 31.2 8.3 48.0 4.0 4.9 115.2 119.2 7.6 7.9 10.9 2.6 4.9 11.7 6.3 5.9 9.4 8.0 10.3 30.2 39.2 3.5 2.0 10.1 10.5 29.6 47.4 3.7 4.1 19.1 15.5 4.8 47.7 8.0 7.4 28.6 3.1 15.3 2.1 5.8 6.0 15.2 15.7 5.8 6.4 3.2 13.3 1.7 14.2 0.3 10.3 7.1 5.0 5.6 1.0 6.2 0.2 0.4 10.8 4.5 14.0 8.9 3.2 0.1 4.8 5.2 0.2 10.9 7.0 16.2 25.0 1.7 1.1 19.8 1.8 4.7 2.1 33.7 3.0 24.6 39.6 3.1 27.3 9.1 11.8 3.5 1.6 32.9 2.6 0.1 11.9 2.4 3.4 1.8 0.2 10.8 1.9 12.8 1.7 17.1 5.0 14.2 2.7 4.3 7.9 1.9 25.9 18.2 2.8 0.2 18.6 0.9 0.8 4.3 14.2 15.0 19.1 14.1 14.5 14.5 2.9 81.3 0.0 2.9 1.3 0.0 0.1 8.2 0.0 9.7 5.6 10.8 9.6 0.0 3.3 7.1 7.4 6.2 0.4 0.2 1.0 5.5 4.5 31.2 48.0 115.2 91.3 30.2 39.2 29.6 47.4 47.7 13.3 ENO3 ENSG00000108515 "Enolase 3" P13929 17 4948092-4957131 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "skeletal muscle: 638.2;tongue: 320.3" "Group enriched" "Detected in many" 4 "HDLM-2: 70.1;HeLa: 30.0;HMC-1: 29.6;RH-30: 48.2;RPMI-8226: 25.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA000793, HPA068284, HPA068721" Enhanced Supported "Plasma membrane,Cytosol" 100000000 "Plasma membrane, Cytosol" "HPA000793: AB_1078742, HPA068284: , HPA068721: " "unprognostic (7.35e-2)" "unprognostic (5.25e-2)" "prognostic unfavourable (7.33e-4)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (5.68e-2)" "unprognostic (2.08e-2)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.04e-3)" "unprognostic (2.21e-2)" "unprognostic (4.63e-2)" "unprognostic (5.34e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "unprognostic (4.50e-2)" 7.6 0.3 0.2 0.6 0.2 0.7 0.5 0.6 0.2 0.2 0.4 0.0 0.1 0.8 0.4 8.5 8.6 0.4 0.1 38.3 0.2 0.1 0.5 5.0 0.4 0.5 0.2 0.0 0.4 0.3 0.3 0.5 0.2 0.1 2.1 0.1 1.2 11.8 0.1 638.2 0.3 0.7 0.4 0.2 0.8 0.4 0.5 0.0 0.6 4.8 320.3 10.5 0.3 0.3 13.3 21.0 27.1 24.8 18.5 23.3 36.0 2.8 6.2 2.8 2.6 2.4 0.6 6.8 5.0 0.6 0.3 0.3 3.0 1.9 5.2 6.8 0.4 3.6 1.0 0.4 0.2 70.1 5.7 5.1 30.0 4.4 0.9 1.5 29.6 4.1 1.0 0.5 1.0 0.3 2.3 9.7 1.5 1.5 1.8 6.2 3.6 2.6 8.3 48.2 25.2 0.7 1.9 1.8 6.8 3.2 2.8 3.6 2.5 1.6 1.5 3.0 5.5 1.3 3.7 6.9 3.8 4.3 1.7 5.0 2.9 13.5 15.6 27.1 21.8 22.5 14.7 13.3 18.7 20.3 21.0 11.1 12.3 19.7 19.7 18.5 24.8 16.6 23.3 36.0 0.2 0.2 0.6 0.2 0.2 0.1 0.2 0.0 0.1 0.0 ENO4 "AC023283.3, C10orf134" ENSG00000188316 "Enolase family member 4" A6NNW6 10 116849512-116911788 "Enzymes, Predicted intracellular proteins" Glycolysis Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.1;epididymis: 12.6;fallopian tube: 13.6" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;MCF7: 8.2;T-47d: 5.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 1.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037937, HPA037938" Enhanced Approved Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA037937: AB_10697089, HPA037938: " "unprognostic (2.92e-3)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (6.55e-4)" "unprognostic (8.38e-5)" "unprognostic (1.88e-1)" "unprognostic (2.21e-1)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (3.74e-3)" "unprognostic (2.06e-1)" "unprognostic (2.20e-3)" "unprognostic (1.18e-1)" "unprognostic (9.77e-3)" "unprognostic (9.87e-5)" "unprognostic (1.08e-2)" 0.7 2.1 4.3 0.6 4.3 0.2 2.2 2.6 3.6 1.7 1.0 8.0 0.9 0.3 4.3 12.6 1.4 13.6 1.3 0.5 6.4 4.7 2.3 2.7 3.9 1.2 4.1 4.8 4.2 3.2 3.7 3.4 0.5 12.1 2.1 0.8 3.0 1.6 1.2 0.2 1.1 0.5 0.9 4.4 0.5 0.8 8.8 1.9 0.2 4.2 0.0 0.6 1.8 0.5 1.8 1.0 0.0 0.6 0.0 1.2 0.1 1.4 0.5 0.5 0.1 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.3 1.1 0.0 0.9 2.0 2.6 0.0 0.7 0.8 0.0 1.5 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.6 0.6 0.0 0.1 0.1 0.0 0.7 8.2 0.0 0.0 1.4 0.2 0.0 0.0 0.0 1.1 0.6 0.9 0.0 2.1 0.1 0.0 5.1 0.0 0.5 0.0 0.7 0.4 1.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.4 0.0 1.6 0.2 0.0 0.3 1.8 0.2 0.0 0.0 0.0 0.2 1.0 1.2 0.1 4.3 4.3 2.6 3.6 6.4 4.7 4.1 4.8 12.1 1.9 ENOPH1 "E1, MASA, mtnC" ENSG00000145293 "Enolase-phosphatase 1" Q9UHY7 4 82430562-82461091 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004985, HPA044607" Enhanced Approved "Nucleoplasm,Nuclear bodies" 140000 Nucleoplasm "Nuclear bodies" "CAB004985: AB_426046, HPA044607: AB_2679019" "unprognostic (6.64e-3)" "unprognostic (3.05e-1)" "unprognostic (6.77e-3)" "unprognostic (1.05e-3)" "unprognostic (1.46e-1)" "unprognostic (1.68e-3)" "prognostic unfavourable (1.74e-5)" "unprognostic (9.99e-3)" "unprognostic (1.18e-1)" "unprognostic (2.17e-1)" "unprognostic (1.59e-1)" "unprognostic (2.05e-1)" "unprognostic (9.30e-3)" "unprognostic (3.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.52e-3)" "unprognostic (3.52e-2)" 10.2 15.4 43.4 12.1 37.1 14.3 16.3 22.9 38.8 13.8 12.7 34.7 5.1 12.2 10.5 23.3 13.5 10.4 9.0 11.1 44.2 34.9 20.8 13.3 11.1 16.0 47.5 26.4 12.9 14.6 17.8 11.7 17.7 31.0 17.2 15.3 8.9 11.4 11.9 9.8 13.1 11.0 11.1 66.2 12.8 13.2 6.1 29.4 14.2 18.0 8.2 18.6 10.7 9.5 13.0 14.1 4.3 10.4 14.4 20.2 12.2 18.8 12.5 22.4 13.9 13.7 13.5 24.6 22.0 14.7 20.1 18.0 22.7 21.1 37.5 23.1 16.6 10.2 29.6 27.8 36.4 22.6 13.8 22.7 12.2 30.2 22.3 37.6 19.7 13.0 29.6 21.0 24.9 20.3 29.3 20.7 26.2 24.3 41.4 22.4 20.6 10.1 29.6 34.4 20.4 32.8 18.7 31.8 19.4 12.5 37.8 27.9 17.1 18.2 14.9 25.0 18.5 24.7 28.9 23.8 20.4 46.8 16.1 23.4 33.5 3.4 8.7 4.3 14.4 10.4 18.0 13.0 17.3 16.5 12.7 11.0 20.2 16.2 0.7 14.4 8.8 14.1 18.4 12.2 43.4 37.1 22.9 38.4 44.2 34.9 47.5 26.4 31.0 29.4 ENOSF1 "HSRTSBETA, rTS, TYMSAS" ENSG00000132199 "Enolase superfamily member 1" Q7L5Y1 18 670324-712676 "Enzymes, Predicted intracellular proteins" "Isomerase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047829 Enhanced "HPA047829: " "prognostic favourable (2.27e-4)" "unprognostic (8.03e-2)" "unprognostic (2.02e-2)" "unprognostic (7.87e-3)" "unprognostic (1.85e-1)" "unprognostic (4.29e-2)" "unprognostic (6.48e-3)" "unprognostic (1.55e-2)" "unprognostic (3.50e-3)" "unprognostic (1.33e-3)" "unprognostic (2.44e-2)" "unprognostic (5.07e-3)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.36e-1)" "unprognostic (5.03e-2)" "unprognostic (1.31e-2)" 8.5 22.0 5.4 11.7 9.4 11.0 10.7 2.2 7.6 12.3 12.7 26.1 15.9 12.1 11.8 10.9 10.4 10.4 11.6 10.0 6.3 5.6 36.7 26.0 15.0 10.4 10.2 6.0 9.6 13.3 13.1 19.8 8.9 12.3 16.3 11.5 18.4 16.4 19.6 9.9 8.3 13.8 14.6 7.0 10.1 12.3 6.5 9.8 12.7 21.2 7.8 8.3 8.8 7.7 2.3 4.3 2.4 3.4 2.9 7.0 2.5 4.1 13.9 7.4 6.6 3.8 3.1 5.3 5.8 7.1 3.7 5.4 12.6 12.0 6.9 1.9 5.4 3.2 9.6 8.3 2.7 3.2 5.0 11.1 15.9 7.3 13.5 19.6 2.8 5.9 9.4 3.7 6.4 8.0 7.6 7.0 5.6 12.5 11.9 6.0 5.9 7.6 5.9 1.8 18.8 11.0 18.1 8.4 3.0 13.8 11.9 2.6 4.0 14.2 6.5 1.9 5.1 8.7 1.8 12.8 11.3 11.2 15.1 7.8 2.6 0.0 1.6 2.4 7.0 3.4 6.9 2.3 4.9 4.1 2.5 0.8 6.9 5.6 0.1 2.9 1.6 4.3 3.4 2.5 5.4 9.4 2.2 7.6 6.3 5.6 10.2 6.0 12.3 9.8 ENPEP "CD249, gp160" ENSG00000138792 "Glutamyl aminopeptidase" Q07075 4 110365733-110565285 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 165.1;kidney: 63.8" "Cell line enhanced" "Detected in some" "BEWO: 4.5;HEK 293: 12.1;MOLT-4: 2.9" "Cancer enriched" "Detected in many" 8 "renal cancer: 41.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005128 Enhanced 37000000 "HPA005128: AB_1844795" "unprognostic (2.73e-3)" "unprognostic (2.84e-3)" "unprognostic (5.16e-3)" "unprognostic (3.48e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" "unprognostic (3.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.47e-2)" "unprognostic (4.49e-3)" "unprognostic (3.43e-3)" "unprognostic (1.52e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-3)" 5.8 1.0 0.4 0.4 0.6 0.0 2.8 0.3 1.0 1.1 54.4 0.4 0.7 11.1 5.3 2.4 0.8 1.4 1.1 2.3 0.5 0.3 63.8 14.5 2.7 0.5 0.4 0.3 1.0 1.0 33.3 0.8 4.4 0.5 1.4 0.0 0.8 0.6 0.5 2.3 0.4 165.1 3.1 0.5 4.7 0.7 0.4 0.4 1.4 2.4 2.0 0.4 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.1 0.0 0.1 0.3 4.5 0.6 0.0 0.2 0.4 0.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 2.9 0.5 0.5 0.0 0.2 0.0 0.5 0.0 0.5 0.1 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 2.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.3 1.0 0.5 0.3 0.4 0.3 0.5 0.4 ENPP1 "M6S1, NPPS, PC-1, PCA1, PDNP1" ENSG00000197594 "Ectonucleotide pyrophosphatase/phosphodiesterase 1" P22413 6 131808016-131895155 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" Biomineralization Hydrolase "Diabetes mellitus, Disease mutation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 22.6;LHCN-M2: 13.5;U-138 MG: 18.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "NK-cell: 4.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB032904, HPA062066" Enhanced "Secreted - unknown location" 2500000 "CAB032904: AB_2099635, HPA062066: " "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.60e-2)" "unprognostic (7.22e-3)" "unprognostic (8.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.00e-1)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (3.28e-3)" 17.2 2.1 0.5 1.9 0.5 0.0 30.5 0.6 0.4 8.5 2.8 1.6 8.3 1.1 25.7 7.1 1.5 6.4 2.6 1.9 0.5 0.7 10.9 19.4 2.0 0.7 1.1 0.0 7.3 17.5 22.2 27.0 28.9 0.8 3.3 1.2 13.4 5.4 6.5 2.1 1.7 2.6 6.8 2.0 1.2 1.7 4.6 0.3 2.0 13.2 6.9 1.4 3.2 7.7 0.6 2.2 1.4 0.3 4.6 1.7 0.1 0.0 0.8 0.8 0.0 22.6 3.5 0.0 5.8 6.0 2.3 6.3 2.5 0.7 0.0 0.5 3.7 0.0 0.8 0.1 9.7 0.2 1.1 0.0 0.7 7.5 0.7 0.0 2.7 5.8 0.2 6.2 0.2 2.7 0.0 1.2 13.5 1.6 0.0 0.0 5.1 0.8 0.0 6.6 0.1 0.1 0.3 2.2 0.0 0.1 0.8 2.6 2.5 0.0 1.8 18.1 0.6 1.2 5.7 2.2 0.0 0.0 8.3 0.0 2.2 1.4 0.2 0.3 0.3 0.2 1.7 0.3 0.3 0.3 2.2 0.6 0.3 0.3 1.0 4.6 0.3 0.3 0.2 0.1 0.5 0.5 0.6 0.4 0.5 0.7 1.1 0.0 0.8 0.3 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 103.7;placenta: 79.0" "Cell line enhanced" "Detected in some" "AF22: 24.7;ASC diff: 33.8;ASC TERT1: 72.2;BJ hTERT+: 41.5;fHDF/TERT166: 26.8;HSkMC: 33.1" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 26.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Intracellular and membrane" 1100000000 "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: " "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favourable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 29.9 15.4 24.0 18.2 42.0 0.7 26.2 4.4 33.3 19.6 8.1 103.7 1.7 20.8 44.8 6.4 2.9 18.7 12.7 3.6 39.8 21.5 24.9 8.9 13.5 31.0 71.5 20.9 5.3 5.2 0.9 4.1 79.0 59.7 8.5 10.6 67.6 3.4 9.2 3.0 5.4 12.1 28.9 102.4 17.3 8.3 9.7 63.9 3.6 3.7 0.8 26.1 13.4 5.7 0.2 3.8 26.8 0.1 0.2 1.8 0.3 0.0 0.0 24.7 0.0 33.8 72.2 0.0 22.7 41.5 9.8 9.4 0.0 0.0 0.0 0.3 26.8 0.0 0.5 0.0 6.9 1.8 0.7 0.0 0.0 0.6 15.1 0.0 0.1 33.1 0.2 20.0 1.0 0.1 0.0 4.0 0.5 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.4 23.9 0.1 0.2 0.0 0.0 16.8 0.1 0.5 26.8 0.1 5.2 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.0 1.8 0.6 0.3 0.2 0.0 3.8 0.0 0.3 24.0 42.0 4.4 33.3 39.8 21.5 71.5 20.9 59.7 63.9 ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 29.0;intestine: 45.4;seminal vesicle: 70.7" "Group enriched" "Detected in some" 18 "HEL: 5.0;Hep G2: 16.6;HMC-1: 7.4" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 74 "basophil: 18.2" "Lineage enriched" "Detected in single" 74 "granulocytes: 18.2" "Low region specificity" "Detected in some" HPA043772 Enhanced "Secreted - unknown location" 480000 "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavourable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" 0.8 7.9 0.5 2.0 0.5 0.0 4.0 2.1 0.4 19.0 18.5 0.2 29.0 9.3 6.2 7.2 0.5 2.3 1.8 0.2 0.4 0.7 11.9 2.7 1.7 0.2 0.5 0.2 0.9 0.2 0.0 0.5 0.4 0.2 3.7 4.8 0.6 14.9 70.7 0.2 0.8 45.4 1.9 0.4 0.5 0.7 1.0 0.2 4.1 0.5 1.2 0.5 0.9 1.2 0.0 0.0 18.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 5.0 0.0 16.6 0.0 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.5 2.1 0.4 0.4 0.7 0.5 0.2 0.2 0.2 ENPP4 "AP3Aase, KIAA0879, NPP4" ENSG00000001561 "Ectonucleotide pyrophosphatase/phosphodiesterase 4" Q9Y6X5 6 46129993-46146699 "Enzymes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 12.0;SCLC-21H: 12.3;U-266/70: 14.9;U-266/84: 17.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016594 Approved "HPA016594: AB_1848171" "unprognostic (9.87e-2)" "unprognostic (1.74e-1)" "unprognostic (2.75e-2)" "unprognostic (2.01e-1)" "unprognostic (2.92e-1)" "unprognostic (1.90e-1)" "unprognostic (8.13e-2)" "unprognostic (5.51e-3)" "unprognostic (1.98e-1)" "unprognostic (1.26e-1)" "unprognostic (8.51e-2)" "unprognostic (4.36e-1)" "prognostic favourable (6.95e-7)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.62e-2)" "unprognostic (2.56e-1)" 12.7 12.5 14.8 6.2 21.9 30.2 14.3 10.1 20.6 9.8 10.5 19.3 31.9 9.5 3.8 10.9 4.8 9.9 7.3 12.9 19.8 15.7 16.8 9.0 17.9 6.9 30.8 15.6 3.4 10.4 22.2 14.1 3.2 23.9 15.0 11.6 7.1 17.5 30.8 20.9 3.6 8.7 8.6 43.2 11.5 12.3 7.1 22.2 4.8 11.3 7.3 5.6 8.0 5.9 3.1 1.8 0.9 2.7 4.6 11.0 3.1 0.0 0.7 0.5 1.0 0.0 0.0 0.0 1.1 1.1 2.7 0.2 1.2 9.0 10.0 8.7 1.4 0.1 2.7 0.4 0.5 12.0 7.5 5.5 0.0 0.0 0.4 6.8 10.2 1.4 0.0 0.0 0.0 0.9 0.0 0.0 1.0 1.1 5.0 0.6 1.8 0.3 3.8 1.8 3.7 5.7 1.1 12.3 0.0 0.0 1.9 0.0 5.1 2.8 0.0 0.0 4.7 0.2 7.4 14.9 17.0 3.4 7.1 0.0 0.9 0.0 0.4 0.9 11.0 1.3 6.4 3.1 4.1 7.9 1.7 1.5 4.0 7.0 0.3 4.6 2.7 1.8 1.4 3.1 14.8 21.9 10.1 20.6 19.8 15.7 30.8 15.6 23.9 22.2 ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.2;kidney: 30.8" "Group enriched" "Detected in some" 7 "HDLM-2: 1.8;Karpas-707: 6.3;SH-SY5Y: 7.1;U-266/70: 5.8;U-266/84: 3.1" "Cancer enriched" "Detected in some" 5 "glioma: 3.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042740 Approved Approved "Golgi apparatus" "Intracellular and membrane" 68000 "Golgi apparatus" "HPA042740: AB_10793984" "unprognostic (4.81e-4)" "unprognostic (1.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.56e-1)" "unprognostic (6.69e-3)" "unprognostic (3.07e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.60e-3)" "unprognostic (3.04e-2)" "unprognostic (1.72e-1)" "unprognostic (2.98e-2)" "unprognostic (2.82e-1)" "unprognostic (3.93e-3)" "unprognostic (2.01e-1)" 0.5 0.6 2.0 1.1 8.0 1.1 1.0 1.7 6.7 0.5 1.3 35.2 0.4 2.0 0.5 6.9 1.3 0.5 0.8 0.5 5.4 3.5 30.8 0.4 0.6 1.1 26.1 3.3 13.7 0.3 0.3 4.1 0.4 19.5 2.7 1.3 7.7 0.9 6.9 0.4 0.5 2.5 0.4 28.2 1.2 1.5 2.7 14.0 0.0 0.5 0.0 3.1 0.9 0.7 0.9 0.8 2.2 0.9 1.5 0.6 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.7 0.3 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.4 0.0 0.2 7.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 5.8 3.1 0.1 0.1 0.1 0.0 2.2 0.9 0.6 0.5 0.5 0.6 0.7 0.4 0.3 0.1 0.9 0.4 0.5 1.7 1.5 0.3 0.8 0.5 0.1 2.0 8.0 1.7 6.7 5.4 3.5 26.1 3.3 19.5 14.0 ENPP7 "alk-SMase, NPP7" ENSG00000182156 "Ectonucleotide pyrophosphatase/phosphodiesterase 7" Q6UWV6 17 79730919-79742222 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 71.1" "Group enriched" "Detected in some" 5 "Hep G2: 2.8;Karpas-707: 5.1;U-266/70: 6.9" "Cancer enriched" "Detected in some" 6 "liver cancer: 6.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "memory B-cell: 1.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024603 Approved "Intracellular and membrane" 440000 "HPA024603: AB_1848174" "unprognostic (4.00e-2)" "unprognostic (1.16e-2)" "unprognostic (6.49e-2)" "unprognostic (4.83e-2)" "unprognostic (1.55e-1)" "unprognostic (2.65e-2)" "unprognostic (1.24e-1)" "unprognostic (1.01e-1)" "unprognostic (8.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (5.21e-2)" "unprognostic (1.25e-1)" "unprognostic (1.80e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.9 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.7 1.3 0.1 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ENTPD1 "ATPDase, CD39, NTPDase-1, SPG64" ENSG00000138185 "Ectonucleoside triphosphate diphosphohydrolase 1" P49961 10 95711779-95869695 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Hydrolase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 59.4" "Group enriched" "Detected in some" 7 "HDLM-2: 56.0;Karpas-707: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 37.4" "Low lineage specificity" "Detected in many" "CAB002494, HPA014067" Enhanced Uncertain Microtubules Microtubules "CAB002494: AB_563557, HPA014067: AB_1848178" "unprognostic (1.14e-1)" "unprognostic (1.01e-2)" "unprognostic (3.11e-1)" "unprognostic (5.67e-2)" "unprognostic (9.68e-3)" "unprognostic (3.45e-3)" "unprognostic (6.31e-2)" "unprognostic (5.26e-3)" "unprognostic (2.73e-1)" "unprognostic (1.28e-2)" "unprognostic (6.40e-2)" "unprognostic (1.41e-1)" "prognostic unfavourable (5.33e-5)" "unprognostic (9.79e-2)" "unprognostic (2.30e-1)" "prognostic favourable (7.89e-4)" "unprognostic (5.09e-2)" 10.4 7.5 7.4 16.2 8.4 15.6 8.8 7.6 6.9 18.9 12.7 13.1 8.7 5.8 59.4 12.8 13.2 15.6 22.2 6.8 7.4 7.4 6.2 3.9 14.8 14.5 8.5 4.9 10.3 2.8 3.0 4.3 24.0 9.9 14.7 9.1 10.8 6.7 12.7 3.3 5.5 12.2 37.2 17.9 25.3 7.5 5.4 7.2 3.5 13.4 12.5 21.1 25.2 12.4 6.0 11.8 37.4 15.2 0.5 5.1 4.6 0.1 0.3 0.9 0.8 0.0 0.0 0.5 0.5 0.4 0.0 0.0 0.5 0.1 1.0 0.6 0.0 0.2 0.0 0.0 0.0 56.0 0.7 0.6 0.4 0.7 0.0 1.5 0.2 0.0 0.0 0.2 0.0 7.4 0.6 46.0 0.0 0.6 0.4 1.5 0.6 0.2 2.3 0.3 0.7 0.5 0.2 0.7 1.0 0.3 1.1 0.7 0.5 1.6 0.8 0.4 0.2 0.6 0.6 6.6 0.9 0.0 0.6 3.1 0.2 0.1 15.2 37.4 0.1 10.7 0.3 6.0 0.6 0.3 11.8 4.6 0.1 0.1 26.7 0.5 2.4 0.7 5.1 4.6 7.4 8.4 7.6 6.9 7.4 7.4 8.5 4.9 9.9 7.2 ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA017655 Supported Supported Vesicles 28000 Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" 16.3 11.5 15.0 21.9 19.8 25.7 15.3 20.3 27.4 15.2 18.5 14.7 15.7 17.0 18.8 17.9 13.3 12.7 14.4 21.0 14.5 12.8 13.0 14.4 19.9 26.0 16.2 12.2 14.7 26.5 30.4 25.2 19.3 20.6 17.6 20.2 18.0 19.5 13.7 14.9 12.2 26.1 16.1 14.5 26.9 19.1 18.7 15.8 17.0 15.8 9.3 30.7 16.7 16.7 9.7 8.0 15.9 9.5 4.4 10.7 6.8 9.9 13.7 17.2 11.9 15.1 19.2 17.6 15.9 15.2 10.8 16.9 19.6 13.2 16.8 11.5 16.0 12.1 7.8 14.4 20.8 4.0 5.4 8.9 8.5 6.8 12.3 4.7 17.7 11.7 17.5 14.4 15.4 15.4 6.1 15.5 18.2 4.5 6.8 5.7 10.0 5.0 6.8 17.2 5.1 13.8 11.8 13.7 13.1 6.0 8.7 11.7 6.4 6.7 19.1 19.7 19.4 22.0 11.7 12.4 5.2 22.0 26.3 5.6 19.7 14.9 6.0 13.7 8.5 9.5 10.0 9.7 8.3 9.1 8.0 6.7 10.7 8.3 15.9 4.4 6.9 7.3 6.5 6.8 15.0 19.8 20.3 27.4 14.5 12.8 16.2 12.2 20.6 15.8 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5" O75356 14 73958010-74019399 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 52.0;kidney: 43.1;liver: 71.4" "Cell line enhanced" "Detected in all" "RT4: 33.8" "Cancer enhanced" "Detected in all" "prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 15.0;eosinophil: 8.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced Approved Cytosol "Secreted to blood" 5000000 Cytosol "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favourable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 3.0 3.6 2.8 9.4 3.8 1.7 3.5 3.0 4.0 2.4 25.8 5.8 3.1 19.3 3.0 2.7 4.5 2.4 6.6 2.6 2.8 2.3 43.1 71.4 2.3 1.3 3.5 2.3 3.3 5.9 1.8 2.7 2.2 5.5 10.2 29.6 3.2 4.7 1.5 3.8 2.7 52.0 3.9 5.5 3.2 11.8 4.5 2.5 2.1 2.7 3.0 3.3 9.5 3.0 1.6 1.6 15.0 2.1 0.6 2.5 1.2 5.3 4.3 4.9 9.1 9.8 9.3 5.7 5.6 4.6 3.7 4.3 3.3 6.4 6.0 2.8 7.6 6.3 4.9 8.1 4.2 5.1 2.3 4.5 3.2 17.8 9.5 2.7 5.3 7.6 8.2 5.3 11.0 7.5 5.0 9.3 5.5 7.6 3.0 3.3 1.5 9.4 3.5 4.7 2.9 6.6 33.8 3.5 3.7 9.5 7.5 5.4 10.9 2.4 6.2 7.6 7.9 4.5 4.1 6.0 9.4 4.9 4.8 5.0 6.8 15.0 1.2 8.3 2.5 2.1 1.3 1.3 1.3 1.7 1.6 1.6 2.1 2.1 0.2 0.6 1.3 0.8 1.4 1.2 2.8 3.8 3.0 4.0 2.8 2.3 3.5 2.3 5.5 2.5 ENTPD6 "CD39L2, dJ738P15.3, IL6ST2, NTPDase-6" ENSG00000197586 "Ectonucleoside triphosphate diphosphohydrolase 6 (putative)" O75354 20 25195693-25226729 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015491, HPA069555" Approved Supported "Golgi apparatus" "Secreted to blood" 18000 "Golgi apparatus" "HPA015491: , HPA069555: " "unprognostic (3.24e-1)" "unprognostic (1.27e-2)" "unprognostic (5.91e-2)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (4.44e-1)" "unprognostic (2.10e-3)" "unprognostic (7.41e-3)" "unprognostic (2.74e-3)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (8.14e-3)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (4.86e-2)" "unprognostic (4.48e-2)" 12.7 19.7 21.8 11.3 46.5 6.7 12.8 33.1 49.1 9.8 31.3 12.1 12.8 31.6 9.4 10.1 9.0 12.5 18.3 27.5 24.9 25.0 13.4 12.9 11.0 7.4 15.1 29.2 16.1 25.6 11.7 20.5 13.2 15.4 25.5 24.5 9.0 36.8 9.7 15.1 6.8 32.2 9.9 8.2 8.3 24.7 16.1 10.5 9.4 10.4 6.1 8.3 10.2 7.1 7.2 17.1 3.0 16.0 8.8 17.9 12.9 20.4 32.4 8.9 17.0 11.2 14.1 19.1 16.8 12.2 14.6 13.5 17.3 15.8 12.4 25.4 16.2 26.8 10.8 25.6 9.7 7.6 9.7 10.1 4.9 39.1 16.8 13.4 15.5 13.2 14.3 18.4 14.0 11.7 13.1 21.7 10.8 19.6 12.5 8.3 5.6 25.4 7.1 27.8 28.4 18.3 12.8 14.2 7.4 4.6 28.5 75.7 20.8 11.3 12.7 17.1 17.8 14.0 19.8 13.6 11.0 5.4 12.2 8.9 32.0 0.0 16.0 3.0 12.7 10.7 17.9 6.1 11.4 10.4 17.1 7.2 12.2 10.6 0.7 8.8 4.8 12.0 10.6 12.9 21.8 46.5 33.1 49.1 24.9 25.0 15.1 29.2 15.4 10.5 ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 48.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.0;RPMI-8226: 8.7;T-47d: 4.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Cytosol" Vesicles "HPA021509: AB_1848185" "unprognostic (3.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.70e-2)" "unprognostic (3.87e-2)" "unprognostic (8.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-2)" "unprognostic (1.08e-5)" "prognostic favourable (7.17e-4)" "unprognostic (2.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" 0.4 0.0 0.4 2.6 0.4 0.0 0.4 0.4 0.4 0.4 19.2 0.4 0.4 18.5 0.4 0.4 0.4 0.3 2.2 0.4 0.5 0.0 2.1 9.8 0.8 0.4 0.4 0.4 0.4 1.8 0.0 4.2 0.5 0.4 0.4 7.5 0.8 4.1 0.4 0.4 0.0 48.1 0.4 0.4 0.4 6.1 0.4 0.4 0.6 0.4 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.0 9.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 1.5 0.2 0.0 0.6 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 1.6 0.0 0.2 0.1 0.4 0.0 0.0 8.7 1.4 0.0 0.3 0.9 0.2 0.0 0.1 4.7 0.2 0.1 0.0 2.4 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.5 0.0 0.4 0.4 0.4 0.4 EOGT "AER61, C3orf64, FLJ33770" ENSG00000163378 "EGF domain specific O-linked N-acetylglucosamine transferase" Q5NDL2 3 68975214-69013961 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019460 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" "Nucleoplasm, Nuclear membrane" Cytosol "HPA019460: AB_1844628" "unprognostic (2.62e-1)" "unprognostic (3.72e-1)" "unprognostic (1.07e-1)" "unprognostic (1.95e-2)" "unprognostic (8.96e-2)" "unprognostic (6.30e-2)" "unprognostic (2.18e-3)" "unprognostic (6.66e-2)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (3.57e-1)" "prognostic unfavourable (8.97e-5)" "unprognostic (7.41e-2)" "unprognostic (4.67e-1)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" 14.9 5.8 3.4 10.1 4.4 3.0 11.9 2.5 4.8 16.8 12.1 4.4 10.2 4.8 23.3 10.4 15.1 11.4 18.1 18.2 3.9 3.6 6.6 5.5 15.8 9.6 4.2 5.0 12.7 7.8 3.9 5.5 15.2 5.1 18.9 5.8 8.7 14.0 24.0 28.0 6.1 7.7 29.4 4.9 10.2 10.1 7.4 2.4 8.3 5.4 14.2 7.3 27.0 9.8 1.7 3.4 5.5 2.2 3.3 9.2 1.8 8.1 2.7 5.4 6.5 7.6 14.9 3.9 11.0 13.5 7.0 9.3 3.7 4.6 0.4 1.7 11.9 2.7 3.7 14.3 8.8 26.3 2.6 8.4 6.2 5.2 8.4 4.7 3.5 12.4 12.2 9.0 11.5 38.4 2.3 5.0 23.4 2.1 0.7 1.5 6.2 1.3 0.3 5.6 3.5 6.0 18.7 0.5 3.0 12.6 1.0 10.0 2.8 6.5 20.3 19.7 6.0 2.2 10.6 2.5 8.3 4.0 7.8 7.3 11.0 5.5 2.2 0.0 3.0 1.9 3.5 1.7 4.8 6.4 3.4 1.2 4.1 4.1 0.3 3.3 0.7 0.6 9.2 1.8 3.4 4.4 2.5 4.8 3.9 3.6 4.2 5.0 5.1 2.4 EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41091786-41180079 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favourable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" 16.8 14.8 19.1 13.9 15.5 45.3 14.5 33.0 20.6 14.8 16.8 15.6 18.9 11.1 18.1 11.6 16.8 15.7 16.5 10.7 16.6 8.3 11.5 12.2 14.1 12.9 16.9 12.7 20.2 15.7 26.4 14.5 27.7 13.8 13.2 12.2 12.3 15.3 17.9 19.5 18.2 17.4 13.8 12.7 15.9 14.7 20.6 18.6 29.3 16.9 10.9 14.1 18.7 22.5 4.3 4.4 9.8 3.9 5.7 3.9 2.3 15.5 11.2 19.0 11.8 12.1 13.0 17.0 7.5 10.9 11.3 10.8 14.2 5.7 16.2 6.6 14.8 12.5 27.4 10.3 12.5 15.8 18.2 12.2 12.8 11.1 13.7 28.8 13.8 12.7 10.8 16.3 13.6 12.5 12.8 22.3 8.9 5.7 8.3 9.0 13.7 7.8 17.1 8.9 10.1 10.7 20.7 6.1 6.4 26.6 13.6 13.0 9.6 16.8 16.1 11.3 13.7 8.0 10.6 15.3 7.2 25.3 8.3 8.9 10.7 5.0 3.2 3.0 3.7 3.9 3.2 4.3 3.6 3.9 4.4 2.9 3.1 2.6 9.8 5.7 2.1 3.0 2.6 2.3 19.1 15.5 33.0 20.6 16.6 8.3 16.9 12.7 13.8 18.6 EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408892 "Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 104.4" "Cell line enhanced" "Detected in some" "CACO-2: 10.3;HaCaT: 9.6;HBEC3-KT: 7.8;MCF7: 8.5;NTERA-2: 32.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 3.4;naive CD4 T-cell: 6.9;naive CD8 T-cell: 5.1" "Lineage enriched" "Detected in single" 9 "T-cells: 6.9" "Not detected" "Not detected" CAB026144 Uncertain 24000000 "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favourable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" 0.4 0.4 0.0 2.0 0.1 0.5 1.2 0.9 0.3 5.7 7.9 0.0 3.3 3.3 0.9 1.4 29.3 1.6 7.9 0.4 0.0 0.0 2.8 10.6 2.9 5.8 0.0 0.0 1.2 2.9 104.4 1.3 5.5 1.1 2.1 0.9 1.3 5.8 3.9 0.3 9.5 12.3 0.4 0.2 0.5 1.8 0.8 0.0 5.1 6.0 16.4 17.2 1.6 11.8 0.0 0.7 0.2 0.1 0.2 6.9 1.6 4.9 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 10.3 4.1 0.0 0.0 0.0 9.6 0.0 7.8 0.0 0.0 0.0 1.0 0.0 0.9 0.0 0.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 1.0 32.1 0.0 0.0 0.0 0.0 0.6 3.9 0.1 0.0 0.0 4.8 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 3.4 0.9 0.4 0.0 6.9 5.1 0.2 0.2 0.0 0.7 0.2 1.6 0.0 0.1 0.9 0.1 0.0 0.0 0.0 0.0 1.1 0.0 EPHA10 "FLJ16103, FLJ33655" ENSG00000183317 "EPH receptor A10" Q5JZY3 1 37713880-37765133 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.6;intestine: 12.6;testis: 24.8" "Cell line enhanced" "Detected in some" "BEWO: 5.1;HDLM-2: 19.2;SCLC-21H: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" HPA027497 Uncertain "Intracellular and membrane" "HPA027497: AB_10601158" "unprognostic (9.27e-2)" "unprognostic (1.21e-1)" "unprognostic (2.94e-2)" "unprognostic (1.24e-6)" "unprognostic (1.06e-1)" "unprognostic (1.11e-2)" "unprognostic (5.39e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.40e-1)" "unprognostic (7.06e-3)" "unprognostic (1.50e-1)" "unprognostic (8.81e-5)" "unprognostic (2.55e-2)" "unprognostic (2.97e-2)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" 0.4 1.1 5.8 1.7 15.6 0.7 1.9 1.3 10.5 0.6 12.6 3.6 0.2 5.8 0.5 6.8 0.8 1.8 2.1 0.4 4.6 7.4 0.5 0.4 0.5 0.6 3.5 5.0 0.4 5.1 1.1 10.8 0.4 6.4 1.4 10.3 1.6 2.4 0.7 0.4 0.6 7.3 1.0 2.3 0.5 5.3 24.8 2.1 0.0 1.0 0.0 0.5 0.6 0.3 0.4 0.3 1.5 0.3 0.8 0.7 0.1 1.5 1.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.6 2.8 0.0 0.4 0.0 0.1 0.1 0.0 0.0 19.2 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 1.0 0.0 0.2 0.7 0.6 0.0 0.0 0.4 0.3 1.7 8.9 0.4 1.1 0.0 0.0 2.8 0.1 0.0 0.0 1.0 0.1 0.0 1.7 1.2 0.0 0.0 0.0 0.0 1.4 0.2 0.1 0.7 0.1 0.4 0.4 0.3 0.3 0.1 0.4 0.6 0.7 1.5 0.8 0.3 0.3 0.2 0.1 5.8 15.6 1.3 10.5 4.6 7.4 3.5 5.0 6.4 2.1 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156087 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 41.9;EFO-21: 40.4;PC-3: 48.0;U-251 MG: 49.2;WM-115: 53.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 115 "plasmacytoid DC: 11.4" "Lineage enriched" "Detected in single" 115 "dendritic cells: 11.4" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 6.7 3.4 1.3 3.1 2.6 0.0 5.2 0.5 2.1 12.1 4.9 1.6 1.9 4.3 7.8 3.8 51.2 4.6 16.7 6.4 1.1 0.8 5.7 8.2 6.6 4.7 2.7 1.3 4.5 10.2 2.2 2.8 8.9 3.4 5.8 2.6 5.4 31.0 2.8 3.4 12.7 13.1 2.7 3.0 2.8 6.8 2.4 1.2 1.2 5.7 21.8 25.5 15.2 18.5 0.0 11.4 0.0 0.0 0.0 0.0 0.0 15.4 31.3 8.7 4.2 0.6 0.7 5.1 9.3 13.3 17.0 10.8 13.0 41.9 0.0 40.4 5.3 6.3 2.0 21.6 5.9 0.0 1.4 0.0 9.1 8.3 11.1 0.0 0.0 1.0 8.1 9.2 20.5 18.1 0.0 0.0 10.7 4.9 0.0 0.0 4.2 48.0 0.0 7.9 0.0 18.0 8.0 0.0 1.3 18.2 4.4 1.2 0.6 0.1 22.3 6.1 16.3 0.4 49.2 0.0 0.1 0.1 4.7 0.0 53.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 1.3 2.6 0.5 2.1 1.1 0.8 2.7 1.3 3.4 1.2 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107524-89482134 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 39.0" "Cell line enriched" "Detected in some" 6 "AF22: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavourable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 9.7 1.1 2.3 1.7 4.5 0.2 5.1 1.3 8.7 12.3 5.8 0.6 1.4 2.2 13.9 1.3 6.3 2.6 17.2 10.0 2.2 2.5 1.5 4.4 2.7 3.0 2.5 3.4 4.2 2.8 1.2 3.4 17.5 11.9 39.0 5.9 5.4 3.8 6.8 1.7 1.7 3.5 17.3 2.9 1.2 3.7 1.3 2.0 0.0 16.3 6.0 3.0 11.8 12.2 0.3 0.1 0.5 0.1 0.3 0.2 0.0 0.0 0.0 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 3.7 0.0 0.2 0.0 0.8 0.0 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 11.5 0.0 0.0 0.0 0.5 0.0 0.5 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.5 0.3 0.1 0.1 0.0 0.0 2.3 4.5 1.3 8.7 2.2 2.5 2.5 3.4 11.9 2.0 EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.6" "Cell line enhanced" "Detected in many" "AF22: 35.0;ASC diff: 15.5;CACO-2: 25.6;U-2197: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 3.0;gdT-cell: 3.4;MAIT T-cell: 3.4;memory B-cell: 2.5;memory CD4 T-cell: 5.0;memory CD8 T-cell: 3.3;naive B-cell: 1.8;naive CD4 T-cell: 1.9;NK-cell: 6.0;T-reg: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB028368 Enhanced 8400000 "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavourable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favourable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" 7.1 1.8 8.1 1.9 18.3 3.5 5.2 14.7 29.6 4.9 5.9 3.1 3.2 1.1 6.5 3.1 5.0 6.6 3.3 16.7 19.9 4.4 5.2 0.9 3.7 2.5 2.4 16.4 11.7 1.2 2.0 1.2 1.7 4.9 5.9 4.7 0.8 3.7 6.7 3.1 12.8 4.1 8.2 2.1 3.3 4.0 11.4 2.6 0.5 9.8 3.7 3.2 4.6 4.9 2.5 0.2 3.0 0.0 6.0 5.0 0.7 1.1 1.0 35.0 0.0 15.5 9.6 0.0 8.3 3.6 7.5 2.8 25.6 0.4 0.0 0.0 11.6 3.0 5.4 0.0 3.2 4.1 3.0 0.0 0.3 0.0 0.4 0.0 0.6 3.8 1.9 2.3 0.0 7.1 0.0 0.0 1.9 4.1 0.1 0.0 2.5 0.7 0.0 3.8 0.0 11.7 1.8 6.2 0.0 2.7 0.5 0.6 1.3 0.0 0.0 0.8 1.4 17.1 0.4 0.0 0.0 0.0 3.1 0.0 1.5 3.0 0.0 0.0 3.4 0.0 3.4 2.5 5.0 3.3 0.0 1.8 1.9 0.3 0.2 6.0 0.0 0.2 2.1 0.7 8.1 18.3 14.7 29.6 19.9 4.4 2.4 16.4 4.9 2.6 EPHA6 FLJ35246 ENSG00000080224 "EPH receptor A6" Q9UF33 3 96814581-97752460 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;ovary: 13.2;testis: 15.5" "Group enriched" "Detected in some" 6 "HEK 293: 8.0;U-266/70: 24.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA007397, HPA058047" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA007397: AB_2667821, HPA058047: " "unprognostic (9.87e-2)" "unprognostic (1.67e-2)" "unprognostic (3.42e-4)" "unprognostic (7.21e-5)" "unprognostic (8.51e-2)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (3.14e-1)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.71e-4)" "unprognostic (1.93e-3)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (7.14e-3)" 0.8 0.5 8.7 0.5 9.8 0.3 0.8 27.9 9.9 2.2 5.8 1.1 0.3 0.6 2.2 1.0 2.1 4.2 2.1 1.1 15.4 1.3 1.3 0.5 0.5 0.4 1.1 6.8 13.2 1.4 0.7 0.6 0.5 5.7 2.5 1.8 0.2 0.6 1.7 0.4 0.5 1.1 3.2 0.8 0.4 1.7 15.5 2.8 0.0 4.3 0.0 0.5 2.1 1.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 8.0 0.0 2.0 0.0 0.0 1.9 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.5 0.0 0.1 0.0 2.1 0.0 0.8 24.3 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 9.8 27.9 9.9 15.4 1.3 1.1 6.8 5.7 2.8 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419547 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 110.4" "Group enriched" "Detected in some" 4 "AF22: 8.7;HEK 293: 25.0;RH-30: 23.8;THP-1: 20.3" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" 340000 "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 1.3 1.3 6.0 1.7 24.6 1.2 2.2 21.6 8.6 2.4 24.6 0.0 0.1 2.5 2.0 7.5 14.7 1.7 3.1 4.2 13.8 2.9 6.9 1.3 1.5 1.3 2.4 5.8 3.0 1.3 110.4 5.6 1.6 6.7 17.9 3.6 0.4 8.2 1.9 1.3 1.4 6.5 20.2 4.8 4.7 14.9 2.1 4.4 0.0 1.3 0.0 1.3 9.7 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 25.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.5 0.6 4.4 23.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 20.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.0 24.6 21.6 8.6 13.8 2.9 2.4 5.8 6.7 4.4 EPHA8 "EEK, Hek3" ENSG00000070886 "EPH receptor A8" P29322 1 22563564-22603594 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 9.4;brain: 5.3;lymphoid tissue: 10.3;pancreas: 8.3;testis: 3.5" "Cell line enriched" "Detected in some" 12 "SCLC-21H: 36.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 25.0" "CAB009660, HPA031433" Uncertain "Intracellular and membrane" "CAB009660: AB_2099696, HPA031433: AB_10601371" "unprognostic (8.58e-2)" "unprognostic (8.59e-2)" "unprognostic (3.72e-1)" "unprognostic (1.15e-2)" "unprognostic (4.69e-4)" "unprognostic (3.58e-1)" "unprognostic (7.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" "unprognostic (9.84e-14)" "unprognostic (2.14e-3)" "unprognostic (1.69e-1)" "unprognostic (2.76e-1)" "unprognostic (8.68e-2)" 0.2 9.4 1.6 0.2 3.1 0.2 0.1 1.8 3.9 0.2 0.2 2.2 0.0 1.7 0.1 0.3 0.2 0.1 0.2 0.2 2.0 2.6 0.1 0.1 0.2 0.2 2.1 4.1 0.1 8.3 0.2 1.7 0.1 5.3 0.2 0.2 1.6 0.8 0.2 0.3 0.4 0.2 0.1 1.3 10.3 0.2 3.5 0.6 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 36.4 2.9 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 3.1 1.8 3.9 2.0 2.6 2.1 4.1 5.3 0.6 EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 74.7" "Group enriched" "Detected in some" 4 "HDLM-2: 33.9;HMC-1: 20.1;RPTEC TERT1: 9.2" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Region enhanced" "Detected in all" "cerebellum: 74.7" "Group enriched" "Detected in some" 33 "neutrophil: 15.9;plasmacytoid DC: 15.4" "Group enriched" "Detected in many" 33 "dendritic cells: 15.4;granulocytes: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: " "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" 2.0 1.5 9.0 1.8 16.6 1.5 5.5 74.7 23.6 3.6 3.4 3.4 3.1 2.8 4.1 2.0 3.8 2.8 3.3 1.1 9.4 5.3 2.3 2.9 1.0 3.3 2.8 7.0 1.7 1.1 0.6 3.8 0.9 7.1 3.3 1.4 1.9 3.9 5.1 7.4 6.0 1.7 1.7 6.0 3.4 1.3 16.7 6.0 0.0 11.6 2.9 3.3 4.5 2.6 0.0 15.4 15.9 0.0 0.0 0.4 0.1 0.0 0.0 4.7 0.0 0.1 0.0 0.1 3.5 0.0 0.2 0.0 0.0 0.0 0.6 1.0 1.8 0.0 3.1 0.0 0.6 33.9 0.4 2.5 0.0 0.0 0.0 0.0 20.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.5 0.1 0.1 0.1 1.3 0.0 0.0 0.5 0.1 9.2 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.4 0.2 0.6 2.0 0.3 4.2 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 15.4 0.0 0.1 9.0 16.6 74.7 19.0 9.4 5.3 2.8 7.0 7.1 6.0 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 22.8;HUVEC TERT2: 31.1;TIME: 30.7;U-251 MG: 26.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 2.5;intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" 290000 "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: " "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favourable (4.98e-4)" "prognostic unfavourable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.7 2.9 3.4 15.4 5.4 0.9 2.5 1.9 8.2 3.8 23.9 16.2 4.6 21.6 2.5 3.2 1.1 5.4 4.4 5.4 5.6 6.5 3.5 1.1 3.0 5.5 12.7 3.8 17.9 5.4 6.1 5.4 12.0 8.2 3.3 25.0 2.2 6.6 4.0 0.7 1.8 22.6 4.0 12.1 3.3 2.3 2.9 9.3 0.1 8.4 1.0 2.1 5.3 3.3 0.1 0.6 0.3 2.5 0.1 0.1 0.4 16.7 7.1 6.8 10.9 0.6 0.6 0.0 3.9 0.2 11.8 2.5 2.4 6.7 0.2 8.4 1.7 15.8 4.6 22.8 3.1 0.0 1.6 0.0 0.7 0.0 7.1 0.0 1.7 2.3 7.3 21.1 0.1 31.1 0.6 0.0 2.3 2.5 0.3 0.1 1.6 4.6 2.0 7.0 0.3 5.8 1.6 7.4 7.8 6.8 0.2 0.1 0.4 0.2 30.7 4.7 12.4 11.9 26.8 0.0 0.1 0.0 8.8 0.3 0.1 0.3 2.5 0.1 0.1 2.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.4 3.4 5.4 1.9 8.2 5.6 6.5 12.7 3.8 8.2 9.3 EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561784-184582409 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 49.3" "Cell line enhanced" "Detected in many" "BEWO: 17.2;HaCaT: 23.6;SK-BR-3: 18.3;T-47d: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.1;myeloid DC: 3.1" "Group enriched" "Detected in many" 5 "dendritic cells: 3.1;monocytes: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007698, HPA008184, CAB034350" Enhanced 20000 "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavourable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" 1.4 0.9 4.5 5.0 2.6 0.5 9.0 9.7 5.7 22.7 8.8 2.3 1.7 5.7 10.0 1.9 19.9 3.0 9.7 1.6 4.7 1.8 1.7 1.0 4.7 1.0 3.3 3.7 9.0 49.3 1.1 1.7 6.3 7.2 7.7 9.7 3.8 27.7 3.5 0.7 32.3 5.6 3.5 1.3 1.2 16.0 1.1 4.0 0.2 1.0 15.7 8.4 4.0 13.6 0.0 3.1 0.3 1.1 0.0 0.4 0.4 3.8 1.3 8.9 0.9 2.7 0.2 17.2 0.6 1.1 1.3 0.7 1.2 0.1 0.0 1.7 3.6 23.6 3.2 1.2 0.3 0.1 0.7 0.0 0.2 0.0 0.2 0.0 0.2 0.7 7.7 1.1 0.1 0.0 0.0 0.0 0.6 10.1 0.0 3.8 0.9 1.5 0.9 5.4 0.0 0.0 3.4 1.1 1.3 0.7 18.3 0.8 12.1 0.1 0.0 2.2 3.2 1.1 1.4 0.0 0.0 0.1 0.2 0.0 8.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.1 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.4 4.5 2.6 9.7 5.7 4.7 1.8 3.3 3.7 7.2 4.0 EPHB4 "HTK, Tyro11" ENSG00000196411 "EPH receptor B4" P54760 7 100802565-100827521 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "classical monocyte: 3.6;neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013537 Uncertain 1000000 "CAB013537: " "prognostic unfavourable (8.56e-4)" "unprognostic (1.05e-2)" "prognostic unfavourable (4.33e-4)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (9.51e-3)" "unprognostic (6.63e-2)" "unprognostic (3.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavourable (8.84e-4)" 14.0 20.7 1.8 4.2 2.9 2.2 17.1 1.9 3.0 29.1 9.5 2.9 14.6 4.1 28.8 10.3 11.0 13.1 35.0 19.0 3.4 1.1 16.8 29.8 16.5 12.0 2.2 0.9 24.6 11.6 5.6 3.1 35.5 3.2 13.7 5.4 11.6 10.8 14.7 5.1 14.2 7.0 12.4 2.2 50.5 8.6 12.2 2.1 2.3 10.2 13.1 7.0 7.7 21.5 0.0 1.6 7.4 3.6 0.0 0.0 1.2 12.5 11.1 11.1 32.2 7.1 4.6 32.9 4.9 10.7 7.7 10.1 9.1 9.6 1.6 22.4 5.0 13.1 4.8 12.9 4.1 2.0 8.9 0.4 6.4 14.1 4.1 0.2 0.3 5.4 19.5 4.9 11.4 28.7 23.6 0.6 6.2 21.8 0.2 4.9 19.0 16.7 17.0 5.5 2.9 9.8 6.6 0.0 9.6 7.5 3.5 7.3 8.9 2.2 24.1 9.6 15.3 17.7 7.2 0.1 0.2 0.5 1.4 4.1 17.4 0.0 3.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 7.4 0.0 0.2 0.3 0.0 1.2 1.8 2.9 1.9 3.0 3.4 1.1 2.2 0.9 3.2 2.1 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810092-225845563 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.4;liver: 265.0" "Cell line enhanced" "Detected in many" "ASC diff: 153.8;SiHa: 73.1" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 6.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced 83000 "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favourable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favourable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 39.5 156.4 16.8 5.7 20.1 3.4 31.3 8.3 25.1 31.3 12.6 28.7 15.3 16.6 21.8 15.7 24.9 26.2 17.8 11.5 16.3 11.2 36.8 265.0 24.1 6.9 17.1 14.5 45.6 85.0 39.5 14.0 5.4 23.6 25.9 8.4 27.3 26.3 21.3 16.4 8.8 9.6 18.6 10.7 8.3 12.1 22.7 12.6 3.6 24.9 15.6 14.9 20.9 32.3 0.5 2.2 0.5 6.6 1.4 1.3 2.3 4.4 42.3 1.6 15.6 153.8 16.0 3.4 5.1 6.4 3.7 5.2 8.7 45.0 0.1 19.3 19.2 4.9 4.6 2.4 1.5 0.9 8.0 3.1 17.9 48.8 16.7 1.9 1.8 15.0 5.6 10.5 1.0 2.7 2.2 3.9 6.6 5.1 1.9 3.6 9.1 11.9 4.1 2.0 12.8 11.1 27.9 14.6 1.9 73.1 26.2 6.7 19.4 5.7 8.1 6.3 5.1 8.5 8.1 1.3 6.7 0.5 9.5 2.1 8.3 0.0 6.6 0.2 0.5 1.9 0.9 0.3 0.9 0.5 1.5 0.5 1.3 1.0 0.5 1.4 0.8 2.2 0.7 2.3 16.8 20.1 8.3 25.1 16.3 11.2 17.1 14.5 23.6 12.6 EPHX2 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490779-27545564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 83.9;liver: 87.6" "Cell line enhanced" "Detected in many" "K-562: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 39.2" "Lineage enriched" "Detected in many" 24 "T-cells: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Approved Enhanced Cytosol 720000 Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favourable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favourable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 4.8 25.1 4.8 14.3 6.0 0.4 8.3 5.6 3.3 7.6 56.2 6.1 21.8 29.8 10.3 15.1 15.2 11.3 9.4 7.8 4.1 4.8 44.2 87.6 4.6 5.0 5.8 3.2 11.4 25.3 11.6 14.6 2.9 10.5 17.9 15.6 13.3 18.0 22.7 8.5 11.5 83.9 13.1 4.5 3.5 6.7 5.4 3.9 45.7 7.5 13.2 11.7 7.0 7.4 1.6 0.0 0.0 0.0 1.4 39.2 7.6 8.4 5.7 3.6 4.7 0.2 0.0 2.7 0.7 0.5 0.4 0.1 4.5 5.8 0.0 3.4 2.1 6.1 0.6 1.4 0.3 0.0 2.7 12.5 0.6 13.7 2.0 0.0 2.6 5.1 6.2 0.0 0.7 0.3 28.2 0.1 0.0 2.6 8.1 0.3 5.8 9.9 0.0 0.0 0.2 5.1 1.2 3.0 9.4 6.9 8.2 8.2 12.5 2.3 0.1 0.0 2.3 1.0 0.1 7.3 5.4 0.1 0.2 0.0 0.1 0.0 0.0 0.0 2.9 0.0 4.0 1.6 12.5 4.5 0.0 0.9 39.2 18.0 0.0 1.4 0.0 0.0 9.4 7.6 4.8 6.0 5.6 3.3 4.1 4.8 5.8 3.2 10.5 3.9 EPHX3 "ABHD9, FLJ22408" ENSG00000105131 "Epoxide hydrolase 3" Q9H6B9 19 15226919-15233435 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.8;lymphoid tissue: 29.6;skin 1: 33.1;tongue: 39.6" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;NTERA-2: 5.9;SCLC-21H: 2.6" "Cancer enhanced" "Detected in many" "cervical cancer: 30.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "intermediate monocyte: 4.2;non-classical monocyte: 4.9" "Group enriched" "Detected in many" 18 "dendritic cells: 2.8;monocytes: 4.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012842 Uncertain Approved Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA012842: AB_10601648" "unprognostic (1.39e-1)" "unprognostic (1.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "prognostic favourable (2.27e-5)" "unprognostic (8.83e-3)" "unprognostic (1.50e-1)" "unprognostic (3.90e-1)" "unprognostic (4.36e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-1)" "unprognostic (3.68e-2)" "unprognostic (1.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.01e-2)" 0.2 0.1 0.1 0.2 0.3 0.1 1.0 0.1 0.3 12.5 0.2 0.2 0.4 0.1 0.9 0.3 34.8 1.1 1.7 0.1 0.5 0.1 1.6 0.2 1.6 0.0 0.2 0.0 0.6 0.0 2.2 2.4 0.2 0.4 1.5 0.1 0.6 3.4 0.6 0.2 33.1 0.2 0.2 0.2 1.2 0.5 2.7 0.2 2.4 0.2 39.6 29.6 2.8 13.6 0.0 2.8 0.2 4.9 0.0 0.0 0.5 0.2 0.6 1.0 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.7 0.8 0.5 6.3 0.2 0.3 0.2 0.1 0.0 0.2 0.1 0.3 0.1 0.0 0.5 0.0 0.5 0.0 0.3 0.6 0.0 0.0 0.3 0.4 0.0 1.0 0.1 0.8 5.9 0.8 0.0 0.0 0.1 0.2 1.3 2.6 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.4 0.8 0.1 0.3 0.1 0.6 0.8 0.1 0.2 0.2 0.0 1.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 4.9 2.8 0.0 0.5 0.1 0.3 0.1 0.3 0.5 0.1 0.2 0.0 0.4 0.2 EPM2A "LD, LDE" ENSG00000112425 "EPM2A, laforin glucan phosphatase" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation, Epilepsy, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.9" "Cell line enhanced" "Detected in many" "Daudi: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 5.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Enhanced Nucleoplasm Nucleoplasm "HPA053643: , HPA055468: " "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-3)" "unprognostic (2.92e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.52e-4)" "unprognostic (2.28e-1)" "prognostic favourable (4.08e-7)" "unprognostic (4.12e-4)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" 5.4 6.0 8.8 1.9 9.0 2.2 3.6 4.0 8.9 3.9 11.1 8.6 2.5 3.4 4.8 4.8 8.9 4.3 3.9 19.4 9.6 8.7 8.0 5.7 3.5 3.4 11.9 5.5 5.9 2.9 5.5 3.3 2.0 9.6 6.2 3.4 5.6 3.1 9.2 60.9 2.4 3.3 13.9 13.6 2.5 4.6 3.3 7.1 3.7 4.2 15.7 2.9 10.4 6.0 1.4 1.0 0.3 1.4 5.4 2.4 1.0 1.1 1.7 3.2 6.2 8.0 2.5 1.4 2.9 3.4 2.7 3.4 1.5 1.6 19.9 2.5 3.5 1.7 1.2 1.2 2.5 7.7 1.6 3.2 2.3 2.5 4.9 11.0 2.0 2.0 6.6 1.6 0.5 1.9 1.4 5.1 3.4 2.6 7.3 2.4 3.3 1.7 4.2 2.9 5.8 2.4 1.6 6.0 5.9 5.2 3.1 6.8 1.8 6.4 4.2 2.8 1.3 2.6 2.3 3.7 3.7 8.0 2.4 2.7 4.3 0.0 0.1 0.1 0.4 1.4 1.1 1.3 1.1 0.9 1.0 1.4 1.2 2.4 0.3 5.4 0.3 0.9 0.2 1.0 8.8 9.0 4.0 8.9 9.6 8.7 11.9 5.5 9.6 7.1 EPRS "EARS, GLUPRORS, PARS, QARS, QPRS" ENSG00000136628 "Glutamyl-prolyl-tRNA synthetase" P07814 1 219968601-220046658 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Aminoacyl-tRNA synthetase, Ligase, Multifunctional enzyme, RNA-binding" "Disease mutation, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026490, HPA030052" Enhanced Enhanced Cytosol 29000 Cytosol "HPA026490: AB_1855979, HPA030052: AB_10601466" "prognostic unfavourable (7.25e-4)" "unprognostic (1.19e-2)" "unprognostic (3.94e-2)" "unprognostic (2.60e-2)" "unprognostic (7.98e-3)" "unprognostic (1.12e-2)" "unprognostic (3.41e-3)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (1.30e-1)" "unprognostic (7.13e-2)" "unprognostic (5.12e-2)" "unprognostic (2.32e-2)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.85e-1)" "prognostic unfavourable (2.62e-4)" 25.0 20.4 16.8 18.6 22.2 13.2 20.6 24.2 26.3 19.3 20.4 15.4 13.6 15.8 17.8 15.3 25.2 15.9 11.9 20.1 15.9 18.0 23.3 31.6 17.4 20.8 21.7 16.1 21.3 32.7 47.1 38.6 15.7 34.9 14.3 23.2 9.4 64.0 16.3 42.9 19.6 23.3 18.9 24.7 22.3 20.1 13.2 20.8 28.0 25.1 25.7 23.4 18.3 16.3 14.7 15.4 6.4 16.6 14.2 19.8 10.7 30.1 19.2 13.9 37.9 29.6 32.8 34.8 39.4 27.6 25.7 28.8 22.7 24.3 57.8 22.0 41.5 32.2 34.8 31.8 34.6 28.3 22.1 31.4 25.9 19.3 32.3 52.1 26.9 23.6 40.8 32.7 41.0 28.0 54.0 45.6 25.0 14.8 22.3 12.7 26.8 39.7 23.7 24.5 56.5 23.5 13.2 33.1 26.0 23.0 38.2 40.2 35.3 56.9 24.9 12.2 22.6 37.5 36.7 30.9 35.1 48.9 28.3 37.5 38.7 4.2 11.9 6.4 14.0 16.6 19.8 14.7 14.1 15.6 15.4 11.5 15.9 16.3 0.4 14.2 13.7 5.0 13.5 10.7 16.8 22.2 24.2 26.3 15.9 18.0 21.7 16.1 34.9 20.8 EPX "EPO, EPP, EPX-PEN" ENSG00000121053 "Eosinophil peroxidase" P11678 17 58192737-58205174 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 27.2;lymphoid tissue: 15.5" "Cell line enriched" "Detected in some" 69 "NB-4: 72.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 41 "eosinophil: 5.5" "Lineage enriched" "Detected in single" 41 "granulocytes: 5.5" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA076792 Enhanced "HPA076792: " "unprognostic (5.67e-2)" "unprognostic (1.73e-2)" "unprognostic (3.36e-2)" "unprognostic (3.30e-1)" "unprognostic (2.18e-1)" "unprognostic (1.34e-3)" "unprognostic (4.83e-1)" "unprognostic (3.16e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-2)" "unprognostic (1.71e-4)" "unprognostic (7.38e-2)" "unprognostic (1.64e-1)" "unprognostic (2.02e-1)" "unprognostic (5.43e-2)" "unprognostic (1.02e-2)" "unprognostic (1.73e-1)" 0.1 0.1 0.3 0.2 0.8 27.2 0.1 2.0 0.6 0.1 0.1 0.5 0.1 0.1 0.4 0.1 0.1 0.2 0.1 1.4 0.3 0.3 0.1 0.2 4.2 0.4 0.2 0.1 0.2 0.1 0.0 0.3 0.2 0.6 0.1 0.0 0.1 0.3 0.1 0.1 0.5 0.1 0.1 0.2 4.5 0.1 0.1 0.1 15.5 0.1 0.1 0.1 0.1 0.1 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 2.0 0.6 0.3 0.3 0.2 0.1 0.6 0.1 ERAP1 "A-LAP, ARTS-1, ERAAP1, KIAA0525, PILS-AP" ENSG00000164307 "Endoplasmic reticulum aminopeptidase 1" Q9NZ08 5 96760810-96808100 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025095, HPA042317" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" 27000000 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB025095: , HPA042317: " "unprognostic (2.33e-3)" "unprognostic (3.45e-1)" "unprognostic (1.84e-3)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.38e-1)" "unprognostic (1.88e-3)" "unprognostic (5.37e-2)" "unprognostic (1.45e-1)" "unprognostic (7.94e-2)" "unprognostic (4.52e-2)" "unprognostic (3.23e-1)" "unprognostic (7.09e-2)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (5.14e-2)" 23.8 13.6 9.3 22.7 11.9 11.6 23.3 14.2 14.6 14.5 23.8 10.1 11.2 30.8 14.7 13.4 12.3 14.3 19.9 16.1 9.7 6.8 13.3 23.7 17.8 16.4 13.5 7.6 15.5 16.5 11.1 39.4 28.2 11.4 13.4 21.9 8.5 13.9 15.2 23.1 17.7 39.7 10.6 17.1 19.5 16.5 5.4 13.8 55.5 13.5 9.8 17.8 15.9 14.1 14.9 15.2 19.8 17.5 19.8 21.8 10.7 7.3 4.7 6.3 5.9 35.0 34.3 18.4 5.4 17.5 13.1 23.0 5.9 26.7 22.0 11.3 10.4 7.6 5.2 11.1 8.2 39.8 2.2 7.1 3.1 4.0 40.1 3.4 13.2 14.2 4.8 15.0 4.6 18.0 3.7 21.4 7.8 3.4 31.6 3.5 3.1 3.0 23.5 8.6 10.9 9.8 11.4 2.3 1.6 8.6 5.8 8.4 5.1 16.4 14.3 11.3 3.8 1.9 8.9 8.0 15.0 17.1 12.1 11.6 6.6 19.8 13.2 15.6 21.2 11.4 19.7 13.0 18.5 18.2 9.5 14.9 21.8 17.4 14.4 19.8 17.5 15.2 12.3 10.7 9.3 11.9 14.2 14.6 9.7 6.8 13.5 7.6 11.4 13.8 ERAP2 "L-RAP, LRAP" ENSG00000164308 "Endoplasmic reticulum aminopeptidase 2" Q6P179 5 96875939-96919716 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 49.3;hTEC/SVTERT24-B: 23.7;MOLT-4: 26.3;TIME: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025618, HPA034498, HPA064360" Enhanced Approved "Golgi apparatus" "Secreted to blood" 7400000 "Golgi apparatus" "CAB025618: , HPA034498: , HPA064360: " "unprognostic (4.62e-2)" "unprognostic (1.60e-1)" "unprognostic (4.98e-2)" "unprognostic (1.56e-1)" "unprognostic (3.14e-1)" "unprognostic (8.71e-2)" "unprognostic (2.60e-2)" "unprognostic (1.17e-2)" "unprognostic (5.03e-2)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.20e-4)" "unprognostic (1.01e-1)" "unprognostic (9.54e-3)" "unprognostic (6.59e-2)" "unprognostic (8.48e-2)" "unprognostic (4.65e-2)" "unprognostic (3.05e-1)" 9.0 6.0 3.1 21.6 3.8 3.5 7.4 2.2 3.5 9.6 37.0 3.1 6.2 17.0 8.3 10.3 12.4 5.7 5.6 5.8 3.3 2.6 8.6 10.8 16.8 30.8 4.2 0.5 18.2 5.9 1.4 11.1 13.6 3.6 9.4 3.1 7.0 9.3 3.5 4.1 4.9 22.4 5.1 8.7 37.6 9.2 2.6 3.1 32.5 11.3 9.6 24.4 11.8 8.7 16.4 10.7 10.9 15.3 24.0 22.4 14.1 0.5 0.6 0.4 0.2 0.5 1.0 0.1 2.1 3.7 2.0 3.3 2.1 49.3 2.9 9.7 3.1 0.7 0.2 17.9 1.6 1.0 2.1 0.1 0.7 2.0 0.7 10.9 5.2 7.3 3.3 23.7 0.1 1.3 0.0 7.3 5.6 0.3 26.3 5.4 0.0 1.0 11.8 4.2 7.7 14.3 4.2 0.9 0.0 0.3 0.2 4.1 1.7 0.4 51.6 1.0 0.3 2.8 6.4 7.2 6.1 1.0 14.4 1.4 0.2 10.9 6.5 7.8 14.2 15.3 18.1 16.4 20.2 17.6 10.7 9.6 22.4 17.0 2.2 24.0 14.4 3.5 18.2 14.1 3.1 3.8 2.2 3.5 3.3 2.6 4.2 0.5 3.6 3.1 ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in many" 27 "SK-BR-3: 263.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 8.8" "Lineage enriched" "Detected in many" 4 "T-cells: 8.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Supported "Plasma membrane,Cytosol" 430000 "Plasma membrane" Cytosol "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: , HPA001060: , HPA001338: , HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavourable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavourable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favourable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" 5.8 2.4 5.2 10.4 7.0 0.1 20.1 4.2 7.0 19.1 46.5 9.1 55.2 21.6 14.9 18.7 40.9 22.7 26.6 24.8 6.3 3.1 37.5 21.5 17.6 3.7 5.1 5.6 19.3 16.2 27.7 8.1 60.8 7.5 23.6 16.6 15.9 28.7 58.1 8.9 35.3 47.2 10.9 4.5 4.0 17.1 6.5 3.7 2.8 35.7 20.8 22.9 19.7 20.3 1.3 0.3 2.1 0.4 0.9 8.8 2.2 3.1 3.8 4.2 2.7 5.1 3.6 5.7 2.2 3.7 4.9 4.2 2.8 8.6 0.2 4.6 5.1 9.8 0.2 5.1 2.3 0.4 3.2 0.1 3.0 4.5 3.0 0.0 0.0 3.5 4.8 3.0 1.8 2.0 0.4 0.1 3.6 4.8 0.5 0.2 7.6 0.9 0.3 1.7 0.4 5.0 9.8 0.8 0.2 4.2 263.9 1.3 7.4 0.1 0.2 2.5 3.3 3.2 1.4 0.4 0.2 0.2 0.2 0.0 8.2 1.6 0.4 0.8 8.8 0.3 0.7 0.9 0.5 2.5 0.3 1.3 1.0 2.5 2.1 0.9 0.2 0.2 0.4 2.2 5.2 7.0 4.2 7.0 6.3 3.1 5.1 5.6 7.5 3.7 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 31.1;MCF7: 20.3;RT4: 24.3;SK-BR-3: 28.6;SK-MEL-30: 38.1;T-47d: 31.7;WM-115: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 5.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.3" "Low region specificity" "Detected in many" "CAB025331, HPA045396" Uncertain Approved "Plasma membrane,Actin filaments" "Secreted - unknown location" 420000 "Actin filaments" "Plasma membrane" "CAB025331: , HPA045396: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 1.1 1.4 11.6 12.6 16.5 0.6 26.8 2.0 16.7 6.8 40.5 40.3 12.0 37.7 2.8 7.5 29.4 5.7 22.9 3.4 18.6 9.0 16.5 33.9 13.4 0.5 23.5 9.3 0.9 21.5 11.4 1.0 15.4 14.9 16.8 29.7 5.5 36.8 22.3 1.1 30.7 41.3 3.2 27.4 0.5 32.9 1.2 23.8 0.0 4.5 7.4 8.5 11.8 14.4 0.9 0.7 5.3 0.6 1.2 1.2 0.2 10.1 0.6 0.8 0.3 0.0 0.0 16.5 0.8 1.9 1.1 1.1 5.5 18.3 0.0 0.2 0.2 8.6 1.2 1.9 0.6 0.2 0.8 0.0 0.3 31.1 0.0 0.0 0.1 0.4 2.5 0.2 0.0 0.0 0.7 0.3 0.1 20.3 0.1 0.3 2.8 0.4 0.1 1.9 0.5 2.1 24.3 0.9 0.3 0.7 28.6 38.1 31.7 0.1 0.0 0.1 1.1 0.6 0.1 0.3 0.1 0.1 0.1 0.0 40.5 5.3 0.4 0.8 0.9 0.4 0.4 0.4 0.7 0.3 0.3 0.9 0.6 1.2 3.3 1.2 0.6 0.7 0.8 0.2 11.6 16.5 2.0 16.7 18.6 9.0 23.5 9.3 14.9 23.8 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease mutation, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.5" "Cell line enhanced" "Detected in some" "AF22: 9.4;EFO-21: 7.0;HEK 293: 5.2;RPTEC TERT1: 7.7;SCLC-21H: 4.3;T-47d: 6.9" "Cancer enhanced" "Detected in many" "breast cancer: 4.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced 140000 "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 1.6 1.9 15.1 1.2 15.0 1.0 13.4 18.6 14.1 7.8 1.1 7.6 8.8 1.1 1.5 1.2 1.3 24.5 1.2 7.0 14.3 6.5 11.9 1.1 2.9 1.2 7.8 10.7 1.3 2.4 10.8 5.1 1.3 8.8 1.7 1.1 2.0 9.7 18.1 3.8 1.8 1.2 1.1 7.3 1.2 1.5 7.6 12.0 0.0 4.5 1.1 1.2 1.4 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.4 0.2 0.0 0.0 0.0 0.0 0.3 0.5 0.1 0.0 0.0 0.0 7.0 1.0 0.4 0.2 0.0 0.0 0.1 5.2 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 7.7 0.4 4.3 0.2 0.0 0.1 0.1 6.9 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 18.6 14.1 14.3 6.5 7.8 10.7 8.8 12.0 ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB005375: AB_2100152, HPA038057: , HPA069266: " "unprognostic (1.10e-1)" "unprognostic (5.48e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-3)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (1.06e-1)" "prognostic favourable (3.26e-4)" "unprognostic (3.36e-2)" "unprognostic (2.44e-3)" "unprognostic (1.94e-1)" "unprognostic (5.47e-1)" "unprognostic (8.99e-2)" "unprognostic (3.45e-2)" 7.4 15.6 11.4 10.6 17.7 6.7 7.1 9.5 23.8 9.4 8.1 11.7 7.8 7.9 11.7 6.0 6.7 10.0 10.1 7.9 9.4 9.1 8.7 13.2 6.5 9.9 8.2 10.5 9.5 13.1 12.9 10.9 7.2 14.0 8.2 6.4 12.5 9.5 11.8 15.9 10.7 7.1 11.2 5.3 9.7 8.3 17.2 7.8 10.8 10.2 5.1 8.3 9.3 6.6 7.8 17.2 5.0 13.9 11.3 9.8 8.7 12.3 6.0 12.6 17.7 7.5 8.9 6.7 17.6 12.1 22.8 17.5 14.0 8.5 4.4 10.1 17.1 6.4 8.8 14.8 8.7 10.6 14.5 7.5 11.5 14.7 15.9 11.9 13.3 10.2 2.3 26.0 14.8 13.2 18.2 5.0 15.7 6.0 7.0 7.9 5.8 10.6 13.5 8.9 3.7 6.5 10.9 7.4 8.0 15.6 11.1 6.2 10.5 15.8 17.1 21.8 11.9 9.2 39.1 11.6 6.7 6.4 6.4 7.3 9.6 0.0 13.3 5.0 7.7 13.9 9.8 7.8 7.4 7.4 17.2 5.8 7.1 7.4 0.4 11.3 10.9 8.3 7.4 8.7 11.4 17.7 9.5 23.8 9.4 9.1 8.2 10.5 14.0 7.8 ERCC3 "BTF2, GTF2H, RAD25, TFIIH, XPB" ENSG00000163161 "ERCC excision repair 3, TFIIH core complex helicase subunit" P19447 2 127257290-127294176 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037153, HPA046077" Approved Enhanced Nucleoplasm Nucleoplasm "CAB037153: AB_796181, HPA046077: " "unprognostic (2.31e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-3)" "unprognostic (1.05e-1)" "unprognostic (8.85e-2)" "prognostic unfavourable (1.62e-7)" "unprognostic (2.74e-1)" "unprognostic (9.13e-3)" "unprognostic (9.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.46e-2)" "prognostic unfavourable (4.30e-6)" "unprognostic (3.71e-1)" "unprognostic (8.50e-2)" "unprognostic (5.73e-2)" "unprognostic (3.92e-2)" 17.4 20.0 26.1 23.8 28.9 20.5 21.0 35.9 32.0 22.1 19.4 19.7 17.1 11.5 21.6 15.7 19.1 23.6 20.4 20.4 23.2 18.8 17.5 17.4 19.4 23.1 19.7 25.8 23.3 22.4 32.0 26.4 16.3 21.5 20.1 17.1 18.3 18.0 21.8 30.1 19.7 17.3 26.1 16.0 24.5 17.4 39.5 20.1 24.1 19.3 15.8 25.9 22.4 20.8 11.8 13.9 7.2 9.7 18.8 16.2 11.7 21.8 15.1 18.6 19.7 20.8 14.2 23.1 20.1 26.2 32.6 31.6 22.9 16.0 16.6 16.7 18.3 19.6 28.4 21.2 28.4 25.9 25.4 20.8 18.4 24.2 15.4 18.1 22.7 14.7 19.9 37.7 16.1 20.9 20.2 10.9 20.5 21.6 25.7 19.5 27.1 23.5 21.2 21.4 13.7 18.2 20.4 22.6 24.4 17.2 26.2 26.3 14.1 20.8 16.6 19.6 22.5 17.8 23.9 19.5 38.1 26.0 17.3 8.7 20.9 6.6 9.5 7.2 16.0 9.7 16.2 11.5 11.8 13.5 13.9 11.8 15.8 10.9 3.1 18.8 7.9 11.3 16.1 11.7 26.1 28.9 35.9 32.0 23.2 18.8 19.7 25.8 21.5 20.1 ERCC6L "FLJ20105, PICH, RAD26L" ENSG00000186871 "ERCC excision repair 6 like, spindle assembly checkpoint helicase" Q2NKX8 X 72204657-72239047 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "NK-cell: 5.3" "Lineage enriched" "Detected in many" 5 "NK-cells: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050492 Approved Supported Nucleoplasm,Centrosome,Cytosol Centrosome "Nucleoplasm, Cytosol" "HPA050492: " "prognostic unfavourable (1.80e-4)" "unprognostic (2.93e-1)" "unprognostic (1.95e-2)" "unprognostic (5.76e-3)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (9.23e-6)" "unprognostic (8.63e-3)" "unprognostic (1.57e-2)" "unprognostic (1.99e-2)" "unprognostic (3.68e-5)" "unprognostic (4.61e-2)" "unprognostic (0.00e+0)" "unprognostic (2.97e-3)" "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (6.41e-2)" 0.4 0.5 0.2 3.1 0.2 6.0 3.0 0.9 0.8 1.5 2.2 0.2 0.2 1.5 0.9 0.8 4.6 0.6 1.0 0.2 0.2 0.3 0.5 0.5 0.8 4.7 0.7 0.2 1.2 0.5 0.0 0.6 0.9 0.9 0.7 2.5 0.2 1.1 0.2 2.6 1.3 2.1 0.5 1.3 4.0 1.5 2.0 0.2 13.1 0.5 2.8 5.6 0.7 1.6 0.5 0.3 0.5 0.2 5.3 1.1 0.4 10.9 9.6 8.9 5.6 0.6 1.1 4.9 11.8 5.4 10.4 10.9 7.8 6.9 17.8 4.5 4.2 9.1 16.6 8.8 18.5 10.1 12.1 6.1 3.3 4.6 0.0 11.9 8.6 0.1 0.5 14.4 2.7 5.7 8.0 4.4 10.5 8.6 11.3 7.0 16.1 14.9 9.5 15.9 3.1 2.6 6.8 7.3 5.2 8.7 5.9 2.2 4.5 2.6 3.5 7.0 11.3 13.2 7.7 3.4 5.3 15.3 4.9 8.3 7.0 0.0 0.2 0.5 0.1 0.1 0.6 0.2 0.5 0.1 0.1 0.5 0.4 1.1 0.3 5.3 0.2 0.3 1.1 0.4 0.2 0.2 0.9 0.8 0.2 0.3 0.7 0.2 0.9 0.2 ERMP1 "FLJ23309, FXNA, KIAA1815" ENSG00000099219 "Endoplasmic reticulum metallopeptidase 1" Q7Z2K6 9 5765076-5833117 "Enzymes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 57.6" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 26.9;RT4: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 4.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055582 Approved "HPA055582: " "unprognostic (1.93e-2)" "unprognostic (3.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.93e-2)" "unprognostic (2.97e-1)" "unprognostic (8.59e-2)" "unprognostic (4.30e-3)" "unprognostic (2.81e-1)" "unprognostic (5.46e-2)" "unprognostic (4.83e-3)" "unprognostic (3.14e-2)" "unprognostic (2.88e-2)" "prognostic favourable (5.83e-10)" "unprognostic (1.41e-1)" "unprognostic (4.00e-1)" "unprognostic (5.77e-2)" "unprognostic (1.36e-1)" 4.0 12.0 5.3 3.6 13.8 1.6 4.8 7.3 12.3 8.5 8.2 20.5 1.5 3.4 4.9 2.9 12.7 4.9 8.8 7.1 6.8 5.8 18.8 3.5 4.7 2.7 18.3 7.0 5.6 4.4 57.6 3.3 5.7 17.0 4.8 8.4 6.9 12.8 3.4 5.2 6.8 4.8 3.2 15.9 2.5 9.1 5.9 11.5 4.6 19.1 4.6 7.2 18.7 8.1 0.2 0.3 0.9 0.5 4.7 2.0 0.3 15.0 14.7 0.6 1.7 7.7 7.4 7.8 1.7 3.8 0.8 0.7 3.5 9.2 3.5 6.7 2.8 10.8 3.2 10.0 1.2 18.5 2.6 18.7 7.7 6.9 1.6 5.3 7.4 3.7 4.4 0.7 4.4 10.4 2.3 3.3 0.9 6.9 0.2 2.0 2.3 2.9 0.5 1.8 4.7 26.9 52.6 3.4 1.0 2.4 17.8 2.8 11.7 6.7 6.1 0.5 1.8 1.1 5.4 3.1 4.4 1.8 2.2 4.4 1.4 0.6 0.3 0.9 1.3 0.5 2.0 0.2 0.6 0.3 0.0 0.0 0.5 0.5 0.0 4.7 0.2 0.3 0.5 0.3 5.3 13.8 7.3 12.3 6.8 5.8 18.3 7.0 17.0 11.5 ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039142-64130819 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 40.4;RPMI-8226: 18.1;U-266/70: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.9;MAIT T-cell: 12.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB009495, HPA027730" Supported "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" 5.5 24.9 2.2 10.6 1.6 8.0 7.7 2.3 1.8 15.8 10.0 3.5 36.1 5.1 11.9 15.0 7.4 7.9 10.6 4.1 1.9 1.7 6.4 21.5 12.3 12.6 2.1 1.6 14.7 44.1 2.9 32.8 10.1 1.8 6.6 3.9 5.0 23.2 34.9 4.2 6.6 11.5 4.1 2.2 9.9 8.8 2.8 1.6 11.6 7.5 5.9 16.7 10.0 7.7 0.1 5.7 12.9 0.7 3.0 12.2 1.0 2.2 1.7 0.9 2.3 2.2 1.8 4.4 1.9 4.2 1.3 1.1 1.2 1.2 2.8 1.3 1.4 1.4 1.2 1.8 3.2 0.8 1.0 2.6 0.9 1.8 13.5 1.2 0.9 2.0 5.1 3.6 11.5 2.4 1.8 40.4 1.1 1.5 1.8 0.5 0.3 1.6 1.9 1.9 18.1 1.1 2.9 3.2 1.9 1.8 3.0 4.4 1.6 2.6 2.3 1.1 2.6 2.5 1.1 38.1 10.0 2.2 2.1 1.3 1.8 12.9 0.7 0.2 4.6 0.4 12.2 0.1 3.0 3.2 0.3 0.1 0.7 1.3 3.3 3.0 0.2 5.7 0.7 1.0 2.2 1.6 2.3 1.8 1.9 1.7 2.1 1.6 1.8 1.6 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690326-23713500 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 64.5;stomach 1: 30.0" "Cell line enriched" "Detected in some" 7 "CAPAN-2: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.6" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 0.7" "Low region specificity" "Detected in all" HPA076875 Approved "Intracellular and membrane" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.3 0.1 8.1 0.2 0.0 0.1 0.1 0.2 11.4 17.3 0.2 0.1 7.0 1.1 0.1 0.9 0.1 64.5 0.1 0.1 0.0 0.2 0.1 1.0 0.5 0.1 0.1 0.1 0.5 0.0 0.8 0.1 0.1 2.6 12.6 0.2 14.0 0.1 0.1 0.1 11.8 0.9 0.1 0.1 30.0 0.1 0.1 0.2 0.1 2.2 7.6 6.3 3.9 0.9 0.6 3.6 0.4 1.5 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.2 12.2 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 3.6 0.4 0.5 0.3 0.3 0.2 0.3 0.3 0.3 0.1 0.9 0.3 0.4 2.1 1.5 0.2 0.6 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 ESD ENSG00000139684 "Esterase D" P10768 13 46771256-46797232 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039700 Approved Approved "Golgi apparatus,Cytosol" 16000000 "Golgi apparatus" Cytosol "HPA039700: AB_10697553" "unprognostic (3.05e-1)" "prognostic unfavourable (5.01e-4)" "unprognostic (7.66e-2)" "unprognostic (1.75e-1)" "unprognostic (1.63e-1)" "prognostic unfavourable (2.16e-4)" "unprognostic (1.73e-2)" "unprognostic (3.31e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (2.91e-2)" "unprognostic (2.71e-2)" "unprognostic (2.18e-1)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" 58.5 30.9 32.0 28.6 29.8 24.2 44.5 23.7 32.0 54.4 37.3 29.0 34.2 31.8 53.2 50.4 54.1 40.6 30.3 45.6 30.7 29.3 58.8 82.2 28.2 31.4 31.7 32.1 61.3 24.9 27.5 47.5 26.4 28.6 55.2 41.7 32.5 31.5 45.2 47.4 29.7 38.4 50.8 37.4 31.1 32.1 32.4 26.7 65.5 78.9 50.9 31.7 62.5 36.9 30.1 48.7 15.1 37.1 29.8 35.7 26.4 21.8 12.7 38.6 26.5 45.3 74.8 10.3 31.5 45.7 43.9 34.2 21.5 26.8 24.9 9.5 37.7 22.4 42.4 37.2 56.2 28.4 44.0 32.1 12.8 33.1 37.1 62.8 13.8 51.1 34.6 28.3 38.1 41.1 31.4 6.7 72.6 21.4 55.6 41.7 10.0 24.2 44.3 22.7 16.8 62.3 8.9 19.1 21.7 14.0 11.9 25.2 22.9 36.0 27.4 16.2 19.1 31.0 29.0 4.6 9.7 21.5 35.0 36.0 21.6 7.7 37.1 15.1 15.0 31.5 24.6 30.1 30.0 23.0 40.8 25.3 35.7 27.9 4.3 29.8 28.0 48.7 24.9 26.4 32.0 29.8 23.7 32.0 30.7 29.3 31.7 32.1 28.6 26.7 ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293643 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 17.9;lymphoid tissue: 30.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 5 "T-reg: 1.8" "Lineage enriched" "Detected in single" 5 "T-cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavourable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavourable (2.01e-5)" "prognostic unfavourable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favourable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" 0.7 0.4 0.2 7.1 0.4 7.2 0.3 0.2 0.5 3.9 2.3 0.4 0.8 4.2 0.6 0.7 17.9 0.2 0.5 1.0 1.1 0.1 1.0 0.9 0.7 4.1 0.2 0.2 0.3 0.2 0.0 0.2 3.0 0.6 0.4 1.5 0.6 2.6 0.2 0.2 2.7 4.4 0.5 0.2 3.0 0.8 10.9 0.3 30.3 0.3 2.5 7.8 0.7 6.2 0.0 0.0 0.4 0.1 0.0 1.8 0.0 12.4 12.7 13.7 11.2 0.3 1.2 8.4 8.2 4.2 14.1 9.0 6.9 11.0 22.5 4.6 3.3 10.4 15.8 4.8 7.4 7.0 16.0 15.1 11.5 5.3 0.0 9.4 12.5 0.4 0.3 8.2 4.0 7.2 20.2 20.4 4.2 13.0 14.8 8.1 11.0 6.9 13.9 14.6 9.3 2.0 5.2 9.8 7.6 6.9 10.2 5.3 16.8 6.3 3.3 7.1 13.8 6.0 11.2 15.1 14.0 15.2 4.1 8.9 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 1.8 0.0 0.2 0.4 0.2 0.5 1.1 0.1 0.2 0.2 0.6 0.3 ETFDH ETFQO ENSG00000171503 "Electron transfer flavoprotein dehydrogenase" Q16134 4 158672125-158709623 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Disease mutation, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 72.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041978 Enhanced "HPA041978: AB_10795605" "unprognostic (7.19e-2)" "unprognostic (2.28e-1)" "unprognostic (2.90e-2)" "unprognostic (5.92e-3)" "unprognostic (1.91e-1)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (7.17e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (1.71e-2)" "unprognostic (5.76e-2)" "prognostic favourable (5.76e-10)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.85e-3)" "unprognostic (1.74e-1)" 11.3 20.1 7.0 3.9 8.6 2.8 12.9 10.3 8.2 5.1 12.5 6.5 6.1 23.0 5.7 6.4 10.9 4.3 5.2 47.8 7.2 5.0 17.3 72.8 4.3 2.9 8.0 5.3 5.0 8.9 11.4 8.8 9.0 8.5 5.2 10.5 7.4 7.2 5.6 33.7 7.7 20.4 8.5 4.8 4.8 9.2 4.1 8.4 4.9 6.0 17.5 5.4 5.8 6.1 5.8 11.0 24.5 13.5 6.2 9.2 5.4 5.6 3.5 5.9 10.7 25.6 15.3 2.8 10.0 10.0 7.4 7.2 1.9 12.5 13.8 2.1 12.1 6.6 11.4 9.9 10.4 21.9 8.3 12.7 8.1 3.3 11.2 10.9 12.1 14.1 12.5 8.0 6.8 14.4 7.0 26.1 11.8 5.8 10.5 5.5 2.3 8.6 8.5 2.0 9.7 11.1 4.9 9.0 3.5 10.0 19.9 9.4 13.5 8.4 6.4 6.0 3.1 8.8 5.1 14.7 18.3 9.4 12.4 9.2 6.4 2.5 13.5 24.5 6.7 13.3 8.1 5.8 6.3 6.8 11.0 5.4 7.8 6.6 4.6 6.2 11.7 8.4 9.2 5.4 7.0 8.6 10.3 8.2 7.2 5.0 8.0 5.3 8.5 8.4 ETHE1 "HSCO, YF13H12" ENSG00000105755 "ETHE1, persulfide dioxygenase" O95571 19 43506719-43527244 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 80.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 57.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028360, HPA029028, HPA029029" Enhanced Enhanced Mitochondria 13000 Mitochondria "HPA028360: AB_10599297, HPA029028: AB_10602092, HPA029029: AB_10601998" "unprognostic (8.04e-2)" "unprognostic (3.33e-1)" "unprognostic (1.50e-2)" "unprognostic (2.45e-1)" "unprognostic (8.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "prognostic unfavourable (9.58e-4)" "unprognostic (7.75e-2)" "unprognostic (2.28e-1)" "unprognostic (5.47e-2)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.27e-2)" "unprognostic (1.75e-1)" "unprognostic (9.72e-3)" "unprognostic (2.73e-2)" 7.7 10.5 5.2 28.3 6.3 13.1 8.8 4.5 6.7 10.9 80.7 4.6 9.6 27.4 7.1 12.2 28.2 7.1 18.4 8.9 4.4 4.1 19.0 21.3 11.4 15.5 5.6 4.9 7.4 12.7 3.0 7.2 16.7 5.1 12.0 72.1 5.6 18.5 6.7 9.4 9.1 40.3 11.8 4.5 11.0 13.2 3.3 4.7 12.0 26.2 23.3 24.4 10.9 13.3 7.9 35.8 7.4 24.3 9.9 20.2 15.1 13.4 17.7 3.6 12.6 19.8 13.5 1.4 20.9 57.0 18.0 18.5 5.3 13.8 0.0 15.7 20.0 11.0 5.2 31.5 4.8 6.7 1.7 3.4 7.7 14.7 9.0 5.0 4.7 13.8 24.8 6.9 19.5 13.3 2.2 22.6 8.8 9.1 5.8 4.6 0.9 8.6 6.6 1.6 3.0 39.1 28.0 0.0 4.5 5.3 19.2 12.5 5.8 8.4 11.2 2.9 12.4 3.5 3.8 6.4 5.0 0.3 12.6 20.8 15.0 7.4 24.3 0.6 17.2 12.7 20.0 7.9 20.2 16.3 35.8 3.4 15.6 14.8 0.7 9.9 8.5 7.1 19.4 15.1 5.2 6.3 4.5 6.7 4.4 4.1 5.6 4.9 5.1 4.7 ETNK1 "EKI, EKI1" ENSG00000139163 "Ethanolamine kinase 1" Q9HBU6 12 22625075-22690665 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010712, HPA029407" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA010712: , HPA029407: " "unprognostic (2.06e-1)" "unprognostic (7.48e-2)" "unprognostic (1.23e-3)" "unprognostic (2.19e-1)" "unprognostic (8.79e-3)" "unprognostic (1.31e-2)" "prognostic unfavourable (5.85e-4)" "unprognostic (3.98e-3)" "unprognostic (8.30e-2)" "unprognostic (7.97e-3)" "unprognostic (2.01e-1)" "unprognostic (1.64e-2)" "unprognostic (4.53e-3)" "unprognostic (2.77e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-1)" "prognostic favourable (1.75e-4)" 15.7 17.7 15.2 41.1 19.4 13.7 16.9 19.7 22.2 12.9 33.2 16.4 14.6 27.2 16.6 24.1 14.7 13.1 27.3 10.4 15.6 23.9 22.0 30.2 19.6 18.5 17.2 15.8 17.2 14.9 15.8 30.6 13.4 18.9 13.8 19.5 15.9 16.7 14.7 8.2 17.8 24.5 10.0 17.1 18.3 53.7 22.3 17.5 33.4 17.6 8.2 16.5 14.2 18.6 16.2 10.7 28.1 17.6 14.0 15.7 13.4 6.7 14.0 15.5 14.3 11.2 11.4 11.6 8.0 6.0 8.3 8.5 10.8 17.0 20.0 7.2 5.2 5.1 13.6 3.8 14.9 16.6 11.0 16.5 6.1 9.2 10.7 15.8 15.2 7.4 3.7 11.1 9.5 10.2 19.8 8.5 10.9 4.6 17.2 32.2 30.0 9.1 15.6 13.8 16.1 13.7 9.1 5.0 8.8 8.7 7.5 12.5 11.8 15.3 8.8 6.6 10.6 8.9 12.0 6.2 7.7 21.5 8.4 10.3 11.0 28.1 11.7 12.1 12.9 17.5 12.7 16.2 14.1 11.9 10.7 13.0 15.7 15.5 11.5 14.0 17.6 9.7 15.3 13.4 15.2 19.4 19.7 22.2 15.6 23.9 17.2 15.8 18.9 17.5 ETNK2 "EKI2, FLJ10761" ENSG00000143845 "Ethanolamine kinase 2" Q9NVF9 1 204131062-204152003 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 65.9;liver: 80.5;testis: 45.0" "Cell line enhanced" "Detected in many" "hTCEpi: 26.4;MCF7: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 4.8;MAIT T-cell: 4.6;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.9;naive CD4 T-cell: 2.9;naive CD8 T-cell: 3.6;NK-cell: 1.5" "Group enriched" "Detected in many" 11 "NK-cells: 1.5;T-cells: 4.8" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 8 "basal ganglia: 24.7" HPA057167 Enhanced "HPA057167: " "unprognostic (1.64e-1)" "unprognostic (4.17e-2)" "unprognostic (2.56e-2)" "unprognostic (7.81e-2)" "prognostic unfavourable (4.11e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-2)" "unprognostic (1.13e-1)" "unprognostic (9.39e-3)" "unprognostic (4.28e-2)" "unprognostic (6.54e-2)" "unprognostic (4.35e-2)" "prognostic favourable (6.50e-4)" "unprognostic (5.50e-3)" "unprognostic (4.69e-2)" "unprognostic (2.00e-2)" "unprognostic (1.20e-1)" 3.3 2.3 4.0 0.8 4.7 0.9 6.3 0.9 4.0 5.1 1.6 1.9 6.5 0.8 3.1 11.0 8.3 4.9 1.9 2.6 2.6 2.5 65.9 80.5 1.2 2.0 2.7 1.9 13.1 4.3 6.2 8.8 2.3 2.7 3.8 0.9 4.8 7.6 7.8 0.6 5.1 0.8 2.4 1.5 2.4 1.1 45.0 1.9 1.1 4.0 3.9 12.9 3.8 6.2 0.2 0.0 0.2 0.2 1.5 4.8 1.0 5.2 1.8 5.3 10.1 2.0 0.6 5.3 5.4 12.0 7.5 3.3 9.0 2.6 0.2 9.1 1.3 4.7 9.3 7.6 5.2 0.2 8.4 0.1 1.0 13.8 8.0 0.2 0.3 2.7 26.4 1.6 0.3 5.4 0.7 0.2 0.9 25.5 1.5 0.1 11.1 4.0 0.4 6.3 0.2 6.5 2.0 1.4 7.6 3.4 16.1 2.5 15.6 0.3 0.3 2.1 11.7 0.4 3.9 0.2 0.1 0.2 0.1 0.2 3.0 0.1 0.2 0.0 4.8 0.0 4.6 0.0 1.3 2.9 0.0 0.2 2.9 3.6 0.2 1.5 0.1 0.0 0.7 1.0 4.0 4.7 0.9 4.0 2.6 2.5 2.7 1.9 2.7 1.9 ETNPPL AGXT2L1 ENSG00000164089 "Ethanolamine-phosphate phospho-lyase" Q8TBG4 4 108742040-108763054 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.5;liver: 111.0" "Cell line enhanced" "Detected in some" "HeLa: 10.8;Hep G2: 4.2;NTERA-2: 2.2" "Group enriched" "Detected in some" 23 "glioma: 7.9;liver cancer: 21.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044546, HPA072938" Approved Approved Nucleoplasm Nucleoplasm "HPA044546: AB_10962867, HPA072938: " "unprognostic (5.20e-3)" "unprognostic (1.33e-1)" "unprognostic (3.93e-1)" "prognostic favourable (9.52e-5)" "unprognostic (5.93e-3)" "unprognostic (3.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.32e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (1.93e-1)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (9.48e-2)" 1.2 1.9 50.8 1.3 51.3 1.2 1.3 7.9 53.5 1.3 1.2 13.4 0.0 1.3 1.4 1.2 1.3 1.2 1.4 3.2 37.5 20.1 6.2 111.0 1.2 1.2 26.0 28.7 1.3 1.2 1.4 0.1 1.2 15.7 1.2 1.2 0.5 19.9 1.3 1.6 1.2 1.2 1.2 7.3 1.6 10.4 1.5 18.7 0.0 1.9 0.0 1.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.1 10.8 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 2.2 0.5 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.9 0.2 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.8 51.3 7.9 24.9 37.5 20.1 26.0 28.7 15.7 18.7 EXD2 "C14orf114, EXDL2, FLJ10738" ENSG00000081177 "Exonuclease 3'-5' domain containing 2" Q9NVH0 14 69191511-69244020 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002906, HPA005848" Uncertain Approved "Intermediate filaments,Mitochondria" Mitochondria "Intermediate filaments" "HPA002906: AB_1078767, HPA005848: AB_1078768" "unprognostic (3.36e-2)" "unprognostic (1.61e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (2.85e-1)" "prognostic unfavourable (8.47e-4)" "unprognostic (9.91e-2)" "unprognostic (8.03e-2)" "unprognostic (2.46e-1)" "unprognostic (4.64e-2)" "unprognostic (8.97e-2)" "prognostic favourable (2.08e-9)" "unprognostic (1.16e-1)" "unprognostic (3.06e-2)" "unprognostic (8.75e-2)" "unprognostic (2.14e-2)" 8.1 7.7 14.3 5.0 19.0 2.3 10.6 20.4 20.1 15.8 8.8 21.7 10.2 7.2 14.4 13.6 10.7 14.5 8.6 8.9 13.8 12.0 11.5 6.0 9.0 4.0 13.7 13.3 12.4 24.9 21.9 13.2 8.0 13.9 11.4 10.0 9.6 17.0 12.1 10.3 7.0 6.8 11.0 20.7 5.8 8.7 20.0 12.6 5.0 12.4 5.2 5.9 10.5 7.9 4.1 7.4 10.9 3.4 3.6 6.0 3.1 18.8 8.9 6.9 10.1 4.2 5.1 8.7 9.4 8.0 8.8 11.7 7.5 13.3 0.0 7.0 9.8 10.7 7.6 9.5 10.0 4.7 9.1 5.5 3.3 4.4 16.6 4.0 5.3 10.3 15.8 9.0 5.9 12.4 3.4 7.3 8.3 9.5 2.3 6.1 7.4 8.9 0.0 6.6 6.6 13.0 7.0 13.4 12.0 7.0 14.8 6.9 19.7 3.5 9.8 8.2 5.8 6.6 4.8 5.6 7.4 0.0 0.0 4.4 6.1 10.9 3.4 2.9 3.3 1.9 6.0 4.1 3.5 3.3 7.4 2.4 4.2 6.0 0.4 3.6 1.7 5.8 2.4 3.1 14.3 19.0 20.4 20.1 13.8 12.0 13.7 13.3 13.9 12.6 EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111853 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease mutation, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 66.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 55.1;fHDF/TERT166: 55.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain 9600000 "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavourable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavourable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavourable (4.64e-4)" "unprognostic (1.85e-1)" 13.8 11.9 5.8 20.5 4.6 2.1 16.5 7.3 7.4 13.3 17.1 4.1 8.7 23.2 11.5 12.5 11.2 8.8 19.3 14.4 4.6 3.1 8.8 66.4 19.9 8.3 3.0 6.8 10.4 17.9 7.1 6.4 15.6 4.8 9.8 16.0 13.2 9.8 13.3 4.2 12.3 32.0 16.8 4.3 20.1 11.5 5.0 2.7 8.7 12.0 10.3 7.2 11.0 18.5 0.8 1.7 1.2 4.5 0.7 2.4 1.0 17.2 5.0 7.5 2.9 13.6 11.0 3.4 32.3 55.1 23.8 21.9 5.1 1.7 0.3 14.5 55.7 10.9 3.3 18.9 33.5 6.5 5.6 0.6 4.7 4.1 6.4 0.0 1.2 6.9 5.1 28.9 26.6 14.6 0.4 4.8 11.0 1.4 0.8 0.0 2.4 6.4 0.0 2.8 0.5 9.4 6.3 2.3 2.2 4.9 2.3 4.8 3.2 0.2 19.4 20.1 18.4 18.4 9.5 2.7 2.7 1.6 18.6 0.0 5.3 0.3 4.4 0.2 0.2 4.5 1.3 0.8 0.5 0.6 1.0 0.1 0.5 0.9 1.2 0.7 2.2 1.7 2.4 1.0 5.8 4.6 7.3 7.4 4.6 3.1 3.0 6.8 4.8 2.7 EXT2 SOTV ENSG00000151348 "Exostosin glycosyltransferase 2" Q93063 11 44095549-44245429 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078409 Supported "Golgi apparatus" 20000000 "Golgi apparatus" "HPA078409: " "unprognostic (5.87e-2)" "unprognostic (3.05e-3)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.42e-1)" "prognostic unfavourable (2.50e-4)" "unprognostic (1.77e-3)" "unprognostic (2.22e-2)" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.70e-2)" "prognostic unfavourable (5.36e-6)" "unprognostic (7.07e-3)" "unprognostic (2.97e-1)" "unprognostic (3.85e-1)" "unprognostic (1.36e-2)" 24.5 19.5 11.6 17.2 18.5 6.6 25.8 14.5 23.0 26.8 25.0 15.5 17.5 17.6 37.1 25.5 16.7 26.0 23.4 22.7 11.7 13.0 19.2 36.3 22.3 16.8 11.8 12.3 29.3 21.8 25.7 17.3 58.0 16.2 23.7 20.6 22.9 24.7 22.8 16.9 20.2 34.0 35.0 12.2 18.7 19.3 20.0 11.4 16.2 24.7 16.7 13.0 20.2 23.2 6.7 14.9 13.0 12.0 17.8 17.6 9.8 12.9 17.9 9.7 30.2 44.8 33.0 13.4 40.2 50.3 23.8 32.4 12.7 8.9 8.9 18.3 47.0 20.6 10.4 28.5 28.8 17.9 14.3 8.2 9.4 9.7 17.7 8.2 17.8 25.6 18.9 14.4 22.5 33.8 11.0 16.2 17.3 9.9 5.7 5.0 10.4 12.8 7.2 27.8 4.5 13.7 12.3 7.0 7.8 25.4 10.4 6.7 17.3 8.8 30.5 32.2 21.1 31.5 25.7 7.3 9.5 6.5 21.2 6.4 34.3 9.3 11.9 13.0 15.6 12.0 17.6 6.4 12.5 14.4 14.9 6.7 11.9 11.7 2.6 17.8 8.5 5.1 9.6 9.8 11.6 18.5 14.5 23.0 11.7 13.0 11.8 12.3 16.2 11.4 EXTL1 "EXTL, MGC70794" ENSG00000158008 "Exostosin like glycosyltransferase 1" Q92935 1 26019884-26036464 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.1;heart muscle: 6.0;skeletal muscle: 20.5" "Cell line enriched" "Detected in some" 10 "WM-115: 57.4" "Cancer enriched" "Detected in some" 13 "melanoma: 21.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA037749 Approved "Intracellular and membrane" 68000 "HPA037749: AB_10805350" "unprognostic (2.00e-1)" "unprognostic (1.10e-2)" "unprognostic (8.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.47e-2)" "unprognostic (6.14e-3)" "unprognostic (3.78e-2)" "unprognostic (1.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.44e-2)" "unprognostic (3.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-3)" "unprognostic (2.27e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-2)" 0.6 2.1 15.3 0.6 9.5 0.5 2.0 1.1 21.1 1.3 0.6 1.4 0.0 0.7 2.5 0.7 1.5 1.7 1.2 6.0 12.7 3.7 0.7 0.5 0.7 0.8 3.7 7.9 2.3 1.0 0.5 0.5 1.0 2.9 1.2 0.6 2.7 0.8 0.9 20.5 1.6 0.7 2.9 2.7 2.2 0.6 1.0 0.8 0.0 0.9 3.2 0.6 0.9 0.2 0.1 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 57.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.8 0.3 0.0 0.0 0.0 0.1 0.0 0.1 15.3 9.5 1.1 21.1 12.7 3.7 3.7 7.9 2.9 0.8 EXTL2 ENSG00000162694 "Exostosin like glycosyltransferase 2" Q9UBQ6 1 100872372-100895998 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020716, HPA068921" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" 83000000 Nucleoplasm Cytosol "CAB020716: , HPA068921: " "unprognostic (3.14e-1)" "unprognostic (6.34e-2)" "unprognostic (1.50e-2)" "unprognostic (8.20e-2)" "unprognostic (9.07e-3)" "unprognostic (1.25e-1)" "prognostic unfavourable (1.64e-5)" "unprognostic (7.81e-3)" "unprognostic (1.10e-2)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" "unprognostic (3.00e-1)" "unprognostic (3.17e-2)" "unprognostic (6.84e-2)" "unprognostic (7.83e-2)" "unprognostic (1.24e-2)" "unprognostic (4.34e-2)" 7.5 23.0 9.8 4.1 19.9 1.7 10.4 14.7 22.8 13.4 8.7 8.1 9.9 4.5 16.7 13.1 6.0 10.1 10.3 8.2 9.5 13.3 11.2 10.0 7.6 3.4 14.0 12.0 18.8 7.7 17.5 18.7 21.8 20.1 12.3 7.1 8.6 6.0 11.4 5.3 5.9 4.6 15.4 11.4 5.4 6.2 9.7 16.3 6.4 9.3 5.0 3.4 9.0 6.2 2.1 7.4 3.3 1.1 5.3 5.6 1.9 5.1 2.7 19.8 20.7 22.0 16.2 12.6 8.9 14.6 7.0 15.7 2.5 3.9 5.7 8.6 8.1 5.0 7.2 7.6 14.2 11.6 5.0 7.0 9.6 7.1 7.2 10.9 3.7 19.2 2.7 14.0 2.7 25.5 8.8 0.7 17.6 2.6 5.7 6.0 24.9 6.0 4.2 20.4 4.7 7.5 3.9 8.2 23.3 6.8 1.7 15.9 4.3 4.9 10.7 17.5 10.3 11.2 9.3 6.1 5.4 3.5 27.9 11.3 5.7 3.3 0.8 0.0 5.6 1.1 2.8 1.9 1.9 3.7 2.5 2.1 2.1 4.8 0.2 5.3 0.9 7.4 0.0 1.9 9.8 19.9 14.7 22.8 9.5 13.3 14.0 12.0 20.1 16.3 EXTL3 "botv, REGR" ENSG00000012232 "Exostosin like glycosyltransferase 3" O43909 8 28600469-28755599 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 10.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025387 Approved "CAB025387: " "unprognostic (1.35e-1)" "unprognostic (1.31e-1)" "unprognostic (5.53e-2)" "unprognostic (1.19e-3)" "unprognostic (9.83e-2)" "unprognostic (2.41e-1)" "prognostic unfavourable (1.14e-5)" "unprognostic (4.25e-2)" "unprognostic (9.29e-3)" "unprognostic (1.05e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-3)" "prognostic favourable (2.47e-5)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (8.91e-2)" "unprognostic (1.39e-2)" 12.1 19.0 15.4 7.9 19.5 4.0 11.6 14.8 26.9 11.3 10.5 16.2 8.8 6.3 15.0 7.9 14.0 13.7 9.6 34.6 15.4 13.4 8.5 6.7 10.1 5.9 11.6 18.1 12.2 13.0 26.1 13.8 15.7 12.9 10.2 6.5 15.2 8.8 14.8 20.7 13.5 6.8 19.8 11.7 9.3 9.6 14.3 10.8 5.4 9.2 8.7 5.9 12.2 9.5 0.8 2.4 10.0 2.3 1.0 3.6 1.5 19.0 14.4 32.2 16.5 8.8 9.1 7.1 14.4 14.6 9.2 7.7 12.2 6.9 5.1 20.9 17.5 12.9 14.8 23.7 9.9 3.7 8.2 7.3 7.2 6.2 5.1 3.5 20.8 10.2 16.1 7.0 6.4 19.6 6.7 6.7 7.2 3.6 6.4 2.3 21.8 5.9 7.7 13.8 3.0 15.7 12.4 6.9 12.0 6.1 3.8 8.3 3.7 4.4 14.9 12.0 28.4 11.1 12.2 3.6 7.2 5.8 10.1 4.4 10.7 4.0 2.0 3.3 3.6 2.3 2.1 0.6 1.3 1.9 2.4 0.8 1.1 0.9 10.0 1.0 2.3 2.3 0.8 1.5 15.4 19.5 14.8 26.9 15.4 13.4 11.6 18.1 12.9 10.8 EYA1 BOR ENSG00000104313 "EYA transcriptional coactivator and phosphatase 1" Q99502 8 71197433-71592025 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Deafness, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 45.5;pituitary gland: 30.8" "Cell line enhanced" "Detected in some" "AN3-CA: 16.4;RH-30: 12.7;SH-SY5Y: 31.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "NK-cell: 9.8" "Lineage enriched" "Detected in many" 4 "NK-cells: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028917 Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA028917: " "unprognostic (3.74e-2)" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.72e-3)" "unprognostic (5.95e-2)" "unprognostic (9.17e-2)" "unprognostic (2.91e-4)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (1.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.13e-1)" "unprognostic (4.22e-12)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (3.81e-4)" "unprognostic (1.25e-2)" 1.0 1.1 2.8 0.6 16.8 0.5 0.6 0.2 6.8 4.0 0.6 1.9 0.0 0.7 0.6 2.2 1.0 2.5 0.8 4.6 2.8 2.2 0.6 0.5 1.0 0.6 2.9 2.8 0.8 0.6 45.5 30.8 0.6 4.2 12.4 0.7 15.3 1.2 4.6 3.2 0.6 0.7 3.9 0.4 0.7 0.9 1.3 5.1 4.4 0.9 2.9 0.6 3.5 5.7 0.8 1.9 1.8 2.3 9.8 2.3 0.2 0.1 0.0 3.7 16.4 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.9 0.0 0.0 2.7 0.0 1.2 0.0 0.0 0.3 0.0 3.6 0.0 0.0 0.1 0.0 0.0 1.2 0.6 0.0 0.0 0.0 1.2 0.9 0.0 12.7 5.4 0.0 0.0 1.3 31.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 1.2 1.8 0.3 0.6 0.9 0.9 1.9 0.8 0.7 1.9 0.7 0.8 1.3 1.4 1.6 9.8 2.3 1.9 2.3 0.2 2.8 16.8 0.2 2.8 2.8 2.2 2.9 2.8 4.2 5.1 EYA2 EAB1 ENSG00000064655 "EYA transcriptional coactivator and phosphatase 2" O00167 20 46894624-47188844 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 47.4" "Cell line enhanced" "Detected in some" "HBEC3-KT: 13.4;SCLC-21H: 20.4;U-266/70: 38.0;U-266/84: 46.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 69.3" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 16 "memory B-cell: 2.4" "Lineage enriched" "Detected in single" 16 "B-cells: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027024, HPA059291" Uncertain Supported Cytosol Cytosol "HPA027024: AB_1848334, HPA059291: " "unprognostic (1.08e-1)" "unprognostic (5.71e-3)" "unprognostic (4.03e-1)" "prognostic favourable (4.30e-5)" "unprognostic (3.32e-2)" "unprognostic (1.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.65e-1)" "unprognostic (7.06e-2)" "unprognostic (2.15e-1)" "unprognostic (2.78e-1)" "unprognostic (4.17e-3)" "unprognostic (1.56e-1)" 10.5 2.0 6.5 2.6 7.4 0.8 13.4 2.4 6.5 47.4 6.4 3.8 21.0 1.0 15.7 10.7 25.9 28.2 2.2 4.3 7.0 4.1 5.2 1.8 2.3 1.3 6.3 4.9 5.2 2.4 11.5 4.7 5.9 9.1 18.5 3.2 15.4 28.6 27.3 2.1 4.2 1.1 2.3 7.2 1.1 8.2 4.9 5.1 14.3 21.4 3.6 14.0 5.5 17.3 2.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.1 13.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.7 1.3 0.0 0.0 0.0 0.0 0.1 0.4 2.4 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 20.4 0.0 0.0 9.1 0.0 1.8 0.0 0.0 0.0 1.6 0.1 3.0 38.0 46.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 7.4 2.4 6.5 7.0 4.1 6.3 4.9 9.1 5.1 EYA3 DKFZp686C132 ENSG00000158161 "EYA transcriptional coactivator and phosphatase 3" Q99504 1 27970344-28088696 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052432, HPA062889" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA052432: , HPA062889: " "unprognostic (3.57e-1)" "unprognostic (2.61e-1)" "unprognostic (2.85e-1)" "unprognostic (8.74e-2)" "unprognostic (1.39e-1)" "prognostic favourable (5.11e-4)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (4.81e-2)" "unprognostic (1.00e-1)" "unprognostic (9.13e-2)" "unprognostic (8.98e-2)" "prognostic favourable (3.15e-6)" "unprognostic (5.17e-2)" "unprognostic (2.79e-1)" "unprognostic (7.60e-2)" "unprognostic (6.11e-2)" 12.8 10.0 14.9 24.0 12.9 8.6 13.3 21.9 13.8 14.7 10.2 14.4 12.8 10.7 14.4 12.4 19.4 11.8 8.1 11.7 10.6 11.8 21.6 11.3 12.5 15.6 11.1 8.8 12.4 12.9 20.9 29.2 13.8 12.9 11.8 11.7 16.4 11.8 13.1 14.5 16.3 12.2 10.5 10.1 14.2 10.0 20.6 13.7 17.4 17.3 12.2 25.0 10.7 13.8 8.6 12.4 10.5 11.2 10.4 12.1 2.6 10.4 4.4 8.9 6.6 10.4 8.1 5.0 7.6 7.3 9.0 8.9 4.3 6.4 16.5 8.5 5.2 10.2 16.4 6.3 10.7 8.7 9.2 18.8 8.9 7.6 6.2 18.1 17.3 4.9 5.7 9.9 6.7 11.5 17.2 6.5 8.0 4.5 11.5 12.1 18.7 5.8 8.8 16.4 10.5 10.6 5.8 10.3 5.7 8.2 5.2 7.3 4.2 4.8 11.0 10.8 5.8 9.9 6.3 9.6 9.6 15.3 7.8 17.6 4.7 7.5 11.2 10.5 12.1 10.4 10.8 8.6 9.5 8.7 12.4 7.6 8.3 9.4 9.7 10.4 8.3 7.7 8.2 2.6 14.9 12.9 21.9 13.8 10.6 11.8 11.1 8.8 12.9 13.7 EYA4 "CMD1J, DFNA10" ENSG00000112319 "EYA transcriptional coactivator and phosphatase 4" O95677 6 133240598-133532120 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Cardiomyopathy, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 65.6" "Cell line enhanced" "Detected in many" "A549: 12.6;HeLa: 35.3;RH-30: 12.0;U-87 MG: 12.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004805, HPA038771, HPA038772" Enhanced Approved Nucleoplasm Nucleoplasm "HPA004805: AB_10669750, HPA038771: AB_10671865, HPA038772: AB_10673119" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.27e-1)" "unprognostic (2.04e-9)" "unprognostic (1.64e-1)" "unprognostic (3.08e-2)" "unprognostic (3.44e-2)" "unprognostic (7.21e-2)" "unprognostic (9.07e-2)" "unprognostic (2.04e-2)" "unprognostic (2.80e-1)" "unprognostic (2.29e-1)" "unprognostic (8.27e-4)" "unprognostic (1.82e-3)" "unprognostic (6.67e-2)" "unprognostic (9.55e-2)" "unprognostic (2.51e-2)" 1.6 3.0 1.2 0.2 1.3 0.1 2.4 0.4 1.2 9.7 0.6 2.5 11.1 0.4 2.6 1.9 0.7 8.3 0.7 6.2 1.5 1.2 6.1 0.4 2.0 0.2 2.1 0.8 1.6 0.4 0.2 7.2 0.2 3.5 6.6 0.4 2.7 0.8 13.9 65.6 0.4 0.5 1.9 3.5 0.6 0.7 7.4 1.4 1.8 2.5 5.5 0.7 2.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 1.2 0.0 0.0 0.0 0.0 0.0 10.1 0.2 1.5 0.0 0.0 0.0 10.0 0.0 0.0 7.6 3.2 0.0 0.0 9.9 1.3 35.3 0.0 0.3 0.0 3.4 2.6 0.0 7.3 2.2 0.0 0.0 5.4 4.0 0.0 0.0 0.0 0.0 0.7 0.1 12.0 0.0 0.0 1.9 1.8 2.0 0.1 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 9.0 3.6 1.6 0.0 12.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.4 1.2 1.5 1.2 2.1 0.8 3.5 1.4 EZH1 "KIAA0388, KMT6B" ENSG00000108799 "Enhancer of zeste 1 polycomb repressive complex 2 subunit" Q92800 17 42700275-42745049 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005478, HPA077684" Supported Supported Nucleoplasm Nucleoplasm "HPA005478: AB_1848340, HPA077684: " "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (2.19e-2)" "unprognostic (8.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.84e-3)" "unprognostic (1.76e-2)" "unprognostic (1.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.55e-3)" "unprognostic (5.22e-3)" "unprognostic (4.11e-3)" "unprognostic (1.48e-2)" "unprognostic (4.60e-2)" "unprognostic (3.29e-1)" "unprognostic (5.39e-2)" "unprognostic (4.74e-2)" 21.7 10.4 15.0 10.1 25.0 9.9 18.7 39.6 26.1 18.4 15.1 21.4 10.0 9.7 29.8 21.2 10.6 18.8 9.7 17.2 19.0 11.2 13.6 5.3 12.6 14.0 13.7 22.0 38.2 8.1 20.0 19.1 9.3 25.6 13.1 12.1 21.5 10.7 19.3 25.4 16.0 14.0 16.4 19.9 16.0 10.6 8.6 16.7 11.9 15.0 7.5 14.9 16.0 15.9 6.2 6.0 18.8 5.4 4.8 8.3 2.3 5.4 5.8 7.9 5.4 31.7 19.2 6.7 8.8 8.1 7.3 7.5 2.7 6.8 8.3 5.5 9.3 12.4 5.1 5.9 10.6 9.2 9.2 2.8 10.7 3.3 10.9 6.2 6.9 10.9 10.7 5.5 13.4 5.9 7.5 11.7 6.4 2.3 10.0 7.9 2.1 3.0 6.6 8.0 8.8 7.6 5.8 5.4 4.3 4.9 2.4 5.8 8.4 4.0 6.1 7.9 3.3 9.2 5.5 12.3 6.2 4.9 5.6 6.4 4.0 10.2 5.2 6.9 5.9 5.4 8.3 5.7 5.2 6.0 1.9 6.2 7.7 5.7 18.8 4.8 3.3 6.0 5.7 2.3 15.0 25.0 39.6 26.1 19.0 11.2 13.7 22.0 25.6 16.7 EZH2 "ENX-1, EZH1, KMT6, KMT6A" ENSG00000106462 "Enhancer of zeste 2 polycomb repressive complex 2 subunit" Q15910 7 148807383-148884321 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.5;lymphoid tissue: 44.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009589 Enhanced Supported Nucleoplasm Nucleoplasm "CAB009589: " "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.57e-1)" "unprognostic (3.30e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "prognostic unfavourable (2.11e-6)" "unprognostic (2.21e-2)" "prognostic unfavourable (1.96e-4)" "unprognostic (2.32e-3)" "unprognostic (1.58e-3)" "unprognostic (1.69e-3)" "prognostic unfavourable (8.18e-12)" "prognostic favourable (6.97e-4)" "unprognostic (1.83e-1)" "unprognostic (2.12e-1)" "unprognostic (6.67e-2)" 2.0 1.7 1.8 10.6 1.6 25.5 1.4 4.9 2.7 2.6 4.8 1.1 0.1 3.8 1.7 2.8 11.0 0.9 3.0 0.9 0.8 0.6 1.7 3.3 2.3 12.6 1.3 0.3 2.2 3.8 0.6 1.7 3.4 1.4 1.4 5.1 1.8 3.2 1.6 3.7 6.4 4.8 1.5 1.2 5.8 2.7 19.6 1.3 44.1 0.9 5.5 12.4 2.6 3.5 1.5 4.7 1.3 3.9 8.5 10.3 1.7 16.9 7.9 27.1 18.0 0.8 1.4 14.8 13.2 5.3 10.9 11.0 11.9 19.6 29.9 6.4 4.9 10.4 13.9 4.5 13.9 42.8 13.9 12.7 9.8 9.2 2.2 28.4 10.5 1.2 2.6 8.1 4.3 6.4 27.1 19.9 9.7 19.2 55.1 23.7 21.5 10.7 34.1 15.2 18.5 5.0 8.1 25.9 16.5 16.6 12.6 4.3 9.2 12.2 3.9 11.6 5.4 23.1 23.6 17.9 19.4 30.1 10.6 19.4 22.7 0.5 2.2 1.3 1.7 1.5 1.3 1.5 3.4 2.9 4.7 0.8 1.9 1.2 0.2 8.5 3.9 1.0 10.3 1.7 1.8 1.6 4.9 2.7 0.8 0.6 1.3 0.3 1.4 1.3 F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186265945-186288806 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 88.9" "Cell line enriched" "Detected in some" 11 "Hep G2: 13.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039808 Approved Vesicles "Secreted to blood" 4400000000 Vesicles "HPA039808: " "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favourable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 2.7 0.1 0.1 5.5 0.2 0.3 0.1 0.1 4.8 0.1 0.1 0.1 10.2 88.9 2.8 0.1 0.1 0.1 0.1 19.0 0.0 0.2 0.1 0.3 0.1 0.0 0.4 0.1 0.1 0.1 0.1 6.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.2 F12 ENSG00000131187 "Coagulation factor XII" P00748 5 177402140-177409576 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "liver: 180.1" "Cell line enhanced" "Detected in some" "HDLM-2: 8.6;MCF7: 10.9;PC-3: 8.1;SH-SY5Y: 5.5;U-937: 5.6" "Cancer enriched" "Detected in many" 21 "liver cancer: 171.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 2.5;eosinophil: 6.9" "Group enriched" "Detected in many" 5 "granulocytes: 6.9;monocytes: 2.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA003825 Approved "Secreted to blood" 1040000 6600000000 "HPA003825: AB_1078790" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (2.93e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "prognostic favourable (4.63e-5)" "unprognostic (6.97e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (4.41e-1)" "unprognostic (6.54e-2)" "prognostic unfavourable (7.09e-4)" "unprognostic (4.11e-2)" "unprognostic (3.69e-1)" "unprognostic (3.40e-6)" "unprognostic (6.48e-2)" 0.1 0.0 0.1 0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.2 180.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.5 1.0 6.9 2.5 0.7 0.3 1.0 0.8 2.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.3 1.3 0.0 0.4 0.0 1.4 0.7 0.4 0.0 8.6 1.8 1.3 0.3 0.9 0.2 0.7 3.0 0.2 1.3 0.1 0.4 0.2 0.4 3.2 0.0 10.9 0.1 2.6 0.0 8.1 0.6 0.2 1.8 1.1 0.0 2.5 5.5 0.3 1.0 0.7 0.4 0.0 0.0 0.2 1.1 0.0 0.3 0.5 0.0 0.1 0.1 5.6 0.6 0.0 2.5 6.9 0.3 0.1 0.2 0.5 0.3 0.2 0.1 0.2 0.0 0.1 0.9 0.7 0.9 1.0 0.0 1.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144085-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 110.1" "Cell line enhanced" "Detected in some" "AF22: 15.3;LHCN-M2: 5.7;RH-30: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 27.6;myeloid DC: 33.7" "Group enriched" "Detected in many" 5 "dendritic cells: 33.7;monocytes: 27.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA001804, CAB002155" Enhanced "Secreted to blood" 1400000000 "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavourable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 56.6 19.4 2.2 11.4 6.5 3.1 57.9 2.2 1.8 13.3 21.8 2.6 2.5 2.2 4.7 35.6 13.4 16.8 12.6 55.4 2.0 2.2 17.5 1.3 14.5 52.7 5.8 1.4 10.2 8.9 5.3 9.3 110.1 7.5 16.4 15.1 11.6 11.5 3.3 18.5 10.4 10.6 20.1 5.0 5.1 11.5 16.7 2.5 2.7 22.4 8.3 6.1 23.7 6.5 0.0 33.7 6.6 27.6 0.0 0.1 63.5 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 28.9 0.5 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 27.6 0.2 0.1 4.9 0.1 0.0 0.0 0.0 33.7 0.0 0.0 0.0 6.6 0.0 0.1 2.4 0.0 63.5 2.2 6.5 2.2 1.8 2.0 2.2 5.8 1.4 7.5 2.5 F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719180-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 593 "liver: 324.8" "Cell line enriched" "Detected in some" 21 "Hep G2: 76.5" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB016780, CAB018650, HPA051476, HPA054698" Enhanced "Secreted to blood" 107500000000 43000000000 "CAB016780: , CAB018650: AB_2246689, HPA051476: , HPA054698: " "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavourable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 324.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 76.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "liver: 68.0" "Group enriched" "Detected in some" 9 "CACO-2: 16.2;Hep G2: 10.1" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "gdT-cell: 1.7;MAIT T-cell: 1.2;memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 17 "T-cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" 3600000 1500000000 Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 68.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.4 0.1 0.1 0.1 0.1 0.1 0.1 FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394265-46413848 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 22.0;RT4: 23.7;SK-BR-3: 12.3" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 19.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol Cytosol "HPA007425: AB_1078820" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "prognostic favourable (1.51e-4)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "prognostic favourable (4.25e-5)" "prognostic favourable (3.63e-5)" "unprognostic (2.66e-1)" "unprognostic (9.97e-2)" "unprognostic (5.00e-3)" 6.1 7.7 11.2 2.5 22.0 7.9 7.9 20.4 21.9 6.9 15.0 40.7 10.1 18.0 3.1 8.2 4.9 10.6 4.6 2.9 14.7 11.7 12.0 18.3 6.7 2.1 19.1 19.3 2.7 18.2 15.1 10.6 3.5 17.6 33.3 12.8 7.4 12.8 8.6 7.1 10.1 17.8 2.3 23.6 2.0 14.3 30.9 18.8 5.6 24.9 3.5 3.5 5.7 4.2 0.1 6.0 19.1 4.7 0.3 0.4 0.9 2.7 0.7 0.4 0.5 0.7 0.5 22.0 0.6 0.3 0.3 0.5 4.0 6.6 0.1 2.3 0.4 9.3 0.4 1.3 0.1 1.2 3.1 0.0 0.1 1.9 0.4 0.8 1.6 0.4 6.3 0.2 0.8 0.0 0.1 0.5 0.0 5.9 0.4 1.2 1.8 0.2 0.5 0.2 0.1 5.2 23.7 2.8 2.1 3.2 12.3 0.1 8.5 8.2 0.0 0.0 0.3 0.6 0.4 1.2 0.5 0.3 0.1 7.5 0.2 0.0 4.7 19.1 0.3 1.2 0.1 0.0 0.3 0.1 5.7 0.1 0.4 0.4 0.2 0.3 0.6 6.0 0.1 0.9 11.2 22.0 20.4 21.9 14.7 11.7 19.1 19.3 17.6 18.8 FADS2 "D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13" ENSG00000134824 "Fatty acid desaturase 2" O95864 11 61792980-61867354 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ductus deferens: 204.5;seminal vesicle: 98.8" "Cell line enhanced" "Detected in many" "ASC TERT1: 148.0;HBEC3-KT: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006741 Approved "HPA006741: AB_1078796" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (8.34e-2)" "unprognostic (4.33e-3)" "unprognostic (4.63e-2)" "unprognostic (2.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.35e-3)" "unprognostic (2.01e-1)" "unprognostic (4.21e-2)" "unprognostic (8.95e-3)" "unprognostic (7.80e-2)" "prognostic unfavourable (1.00e-7)" "unprognostic (6.19e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "prognostic unfavourable (3.42e-4)" 7.1 85.9 34.3 10.0 31.7 7.5 20.2 10.1 48.5 23.7 4.9 28.6 204.5 9.3 19.9 10.3 3.2 8.9 6.6 8.2 24.4 29.9 3.8 38.0 9.7 6.7 28.1 20.1 8.6 3.1 41.5 11.8 12.8 26.4 32.0 4.3 16.7 5.0 98.8 3.0 26.1 3.6 39.3 17.9 3.3 3.6 10.4 24.0 8.4 2.5 3.2 9.2 10.6 6.5 3.5 13.3 6.9 9.0 6.3 9.4 3.8 1.3 52.1 77.4 42.7 70.5 148.0 20.2 8.7 78.7 12.8 35.1 3.3 17.5 0.3 1.2 19.2 1.5 50.6 88.5 5.5 0.6 1.0 29.6 10.4 7.6 55.6 1.8 1.7 55.6 2.7 46.6 4.2 37.8 1.6 24.0 5.9 1.3 16.6 9.8 33.7 13.7 22.5 1.3 72.8 50.9 0.4 23.0 28.0 5.7 0.1 2.2 2.1 21.8 15.3 1.4 13.9 0.9 1.2 11.2 9.8 3.9 1.4 9.8 15.7 4.5 5.7 6.9 9.4 9.0 2.2 1.6 3.5 5.0 10.5 3.5 2.0 4.4 3.1 6.3 7.5 13.3 3.0 3.8 34.3 31.7 10.1 25.2 24.4 29.9 28.1 20.1 26.4 24.0 FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 109.4" "Cell line enhanced" "Detected in many" "HHSteC: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041370, HPA044093" Enhanced Approved Cytosol 230000000 Cytosol "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavourable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" 32.1 17.8 4.6 6.1 3.6 4.7 22.8 2.3 3.3 4.7 8.6 3.1 8.3 4.1 5.1 14.8 4.4 6.8 7.1 6.8 4.1 2.8 18.9 109.4 7.9 6.2 4.0 2.1 7.2 6.5 4.8 4.4 2.3 3.5 4.9 3.4 2.4 5.3 5.4 7.7 2.4 7.6 4.4 5.9 6.0 3.3 9.7 3.0 2.3 4.2 4.9 3.9 4.1 6.1 0.1 16.0 16.9 11.7 3.6 5.8 6.1 4.4 7.5 3.1 3.8 14.5 14.8 7.6 5.7 13.1 6.0 5.2 4.5 8.2 0.0 9.4 12.0 6.6 11.0 13.6 5.9 2.8 6.2 38.1 4.4 23.3 75.2 18.0 21.1 25.6 8.5 5.2 9.4 8.4 15.9 8.1 11.3 6.7 4.9 9.0 2.2 8.6 2.7 4.4 28.5 17.5 5.4 0.1 1.9 6.4 17.7 17.8 13.5 12.3 29.3 11.1 7.0 5.9 9.6 7.4 15.2 3.0 23.1 42.2 6.2 16.9 11.7 1.9 5.8 4.9 1.5 0.1 1.6 3.9 16.0 0.0 2.0 1.8 0.7 3.6 4.8 1.2 1.5 6.1 4.6 3.6 2.3 3.3 4.1 2.8 4.0 2.1 3.5 3.0 FAHD1 "C16orf36, DKFZP566J2046" ENSG00000180185 "Fumarylacetoacetate hydrolase domain containing 1" Q6P587 16 1826941-1840207 "Enzymes, Predicted intracellular proteins" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025530, HPA043226, HPA043534" Enhanced Enhanced Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB025530: , HPA043226: AB_2678370, HPA043534: AB_2678535" "unprognostic (3.71e-1)" "unprognostic (1.25e-2)" "prognostic favourable (8.27e-4)" "unprognostic (1.99e-1)" "unprognostic (6.74e-2)" "unprognostic (1.01e-3)" "unprognostic (2.89e-2)" "unprognostic (4.32e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "prognostic favourable (2.80e-14)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (3.31e-2)" 10.4 17.0 10.4 6.7 9.9 6.5 9.2 8.6 12.7 6.8 21.7 9.3 8.2 26.7 9.8 10.9 14.8 5.8 10.2 15.8 10.9 11.4 46.8 43.6 5.6 5.2 10.1 9.4 7.9 17.4 9.0 11.1 10.4 9.9 8.1 11.1 8.5 9.1 9.8 20.2 12.4 24.8 6.9 8.8 6.3 14.9 6.9 9.5 4.7 12.5 19.0 5.7 9.9 7.9 18.5 23.1 8.6 27.5 19.6 16.0 13.7 8.3 18.8 9.0 15.8 12.0 8.7 5.6 13.7 6.8 9.2 10.1 12.0 8.7 5.3 11.6 8.5 17.2 7.0 11.0 8.3 8.0 16.6 4.8 16.2 27.6 11.7 8.2 9.2 11.4 14.5 8.4 5.6 11.9 4.9 5.6 11.5 38.2 4.4 12.5 5.3 14.1 10.2 12.2 15.0 32.9 10.5 17.6 14.6 17.9 14.4 21.5 21.2 5.6 17.4 15.1 10.8 8.8 7.4 8.1 17.0 6.3 9.6 6.0 6.4 6.5 23.5 8.6 14.4 27.5 13.0 18.5 14.5 15.7 23.1 16.9 16.0 14.9 2.0 19.6 19.1 17.9 14.7 13.7 10.4 9.9 8.6 12.7 10.9 11.4 10.1 9.4 9.9 9.5 FAM105A "FLJ11127, NET20" ENSG00000145569 "Family with sequence similarity 105 member A" Q9NUU6 5 14581775-14615007 "Enzymes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35.4" "Cell line enhanced" "Detected in many" "HeLa: 13.8;HMC-1: 43.3;THP-1: 12.0;U-937: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046638 Uncertain Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA046638: " "unprognostic (1.47e-1)" "unprognostic (6.64e-3)" "unprognostic (1.92e-2)" "unprognostic (1.15e-3)" "unprognostic (6.26e-2)" "unprognostic (1.13e-3)" "unprognostic (2.33e-2)" "unprognostic (2.27e-2)" "unprognostic (6.44e-2)" "unprognostic (2.42e-1)" "prognostic favourable (1.02e-4)" "unprognostic (2.13e-1)" "unprognostic (1.33e-2)" "unprognostic (2.38e-2)" "prognostic unfavourable (7.62e-4)" "unprognostic (3.14e-1)" "unprognostic (8.79e-3)" 5.1 3.5 4.0 7.9 4.9 35.4 5.2 3.1 5.1 6.3 15.4 9.0 4.5 8.3 3.0 5.6 2.9 3.1 4.1 3.0 3.9 4.3 5.2 1.9 28.8 16.7 6.1 3.8 4.0 13.3 1.9 8.7 6.7 7.9 12.6 17.3 10.3 3.1 13.5 1.3 2.6 13.7 3.3 10.8 13.2 5.4 4.4 4.1 3.5 27.2 3.0 6.2 7.1 5.8 0.1 26.7 6.9 26.2 14.1 9.6 16.2 0.0 0.6 1.2 0.0 0.2 0.0 5.2 1.5 1.4 0.4 0.7 1.9 1.3 0.0 0.8 0.7 0.1 2.6 1.2 0.6 0.8 3.6 3.4 13.8 0.3 1.3 0.0 43.3 0.1 0.3 0.2 0.0 0.0 0.0 5.4 0.1 1.0 0.0 1.2 1.9 9.2 0.3 0.5 1.5 0.0 10.4 4.5 5.0 0.7 0.4 0.0 0.4 12.0 0.0 0.6 3.4 0.2 1.1 0.0 0.0 0.0 0.7 20.5 0.2 0.0 26.2 0.1 4.5 12.4 6.0 0.1 5.7 6.1 26.7 0.1 7.8 7.5 6.9 14.1 9.4 19.7 9.6 16.2 4.0 4.9 3.1 5.1 3.9 4.3 6.1 3.8 7.9 4.1 FAM20C "DKFZp547D065, DMP4, G-CK, IMAGE:4942737" ENSG00000177706 "FAM20C, golgi associated secretory pathway kinase" Q8IXL6 7 192969-260745 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Biomineralization "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 80.6" "Cell line enhanced" "Detected in many" "HSkMC: 52.0;U-87 MG: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019823 Approved "Nucleoplasm,Golgi apparatus" "Secreted in other tissues" 160000000 "Golgi apparatus" Nucleoplasm "HPA019823: AB_1848389" "unprognostic (1.94e-1)" "prognostic unfavourable (8.89e-4)" "unprognostic (3.15e-2)" "unprognostic (1.03e-2)" "unprognostic (3.33e-3)" "unprognostic (2.47e-2)" "unprognostic (7.86e-2)" "unprognostic (2.45e-3)" "unprognostic (3.35e-2)" "prognostic unfavourable (9.40e-6)" "unprognostic (1.97e-3)" "unprognostic (2.49e-1)" "unprognostic (3.08e-3)" "unprognostic (1.94e-2)" "unprognostic (3.92e-2)" "unprognostic (2.16e-2)" "unprognostic (3.83e-3)" 27.5 10.2 10.8 19.3 16.6 3.3 25.6 7.4 14.9 8.3 20.1 13.5 15.1 12.9 9.5 6.9 11.1 9.7 15.0 15.0 8.8 7.2 31.8 31.6 12.7 5.1 16.9 5.6 11.8 14.8 2.6 9.2 7.2 15.8 15.0 4.6 8.8 80.6 11.8 20.4 6.8 16.5 17.0 17.0 6.9 20.0 5.9 14.8 0.4 9.6 8.4 4.4 20.5 17.5 0.0 0.6 0.0 1.6 0.2 0.0 0.0 13.8 6.7 0.2 9.6 12.3 20.4 0.0 12.3 20.9 6.7 5.4 0.8 8.5 0.0 6.8 18.4 12.0 1.0 0.6 1.7 2.9 0.6 0.0 3.2 3.7 9.3 0.0 0.9 52.0 1.5 0.2 0.7 4.6 0.0 0.1 1.7 1.8 0.0 0.7 6.5 0.4 1.5 0.4 0.0 5.0 0.0 3.2 0.1 12.8 0.0 1.9 9.1 6.3 12.9 8.4 4.2 7.1 3.7 0.0 0.0 0.0 32.0 0.8 23.8 0.0 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.8 16.6 7.4 14.9 8.8 7.2 16.9 5.6 15.8 14.8 FAM213B "C1orf93, MGC26818" ENSG00000157870 "Family with sequence similarity 213 member B" Q8TBF2 1 2586491-2591469 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 26.3;U-2197: 22.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006403 Approved Approved "HPA006403: AB_1853870" "unprognostic (1.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.03e-1)" "unprognostic (2.83e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "prognostic unfavourable (1.62e-4)" "unprognostic (1.20e-1)" "unprognostic (8.76e-2)" "unprognostic (3.09e-2)" "unprognostic (1.24e-3)" "unprognostic (2.76e-1)" "prognostic favourable (1.28e-4)" "unprognostic (5.22e-3)" "unprognostic (2.03e-1)" "unprognostic (7.91e-3)" "unprognostic (2.20e-2)" 6.0 9.1 14.7 5.7 14.9 3.8 4.6 7.4 20.0 7.9 15.4 6.2 5.2 22.0 4.5 6.7 5.7 10.5 23.7 3.2 15.0 15.5 7.4 3.5 6.0 5.8 11.7 11.0 7.1 4.6 4.4 4.3 8.4 10.7 5.7 7.4 9.0 5.3 7.7 1.8 6.1 20.2 4.8 6.5 7.4 11.7 3.3 4.7 5.4 5.2 0.9 5.2 6.3 3.5 2.1 2.2 1.5 2.3 7.5 6.3 3.2 7.6 4.2 4.3 4.8 2.1 2.4 0.6 6.9 2.9 6.5 2.9 3.0 9.0 1.9 7.0 4.4 6.4 3.8 4.8 2.2 5.8 2.0 4.8 3.3 4.8 5.0 2.7 1.3 3.5 2.5 4.5 1.7 9.2 6.4 3.0 6.5 5.5 6.2 1.1 5.2 16.3 6.8 6.4 5.0 6.8 3.9 5.8 9.6 5.9 26.3 7.9 4.6 1.0 13.3 5.7 6.6 22.5 2.6 2.8 4.3 1.4 5.3 9.1 1.1 1.5 2.0 1.1 3.8 2.3 6.3 2.1 4.2 4.1 2.2 1.5 3.5 5.4 1.5 7.5 2.0 1.0 5.6 3.2 14.7 14.9 7.4 20.0 15.0 15.5 11.7 11.0 10.7 4.7 FAN1 "KIAA1018, MTMR15" ENSG00000198690 "FANCD2 and FANCI associated nuclease 1" Q9Y2M0 15 30903852-30943108 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048198 Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA048198: " "unprognostic (7.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-1)" "unprognostic (3.30e-2)" "unprognostic (6.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.97e-1)" "unprognostic (1.19e-1)" "unprognostic (5.94e-2)" "unprognostic (3.53e-2)" "unprognostic (3.53e-2)" "unprognostic (9.67e-2)" "prognostic favourable (1.42e-6)" "unprognostic (3.73e-1)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" "unprognostic (1.29e-1)" 5.9 8.9 11.6 6.9 17.4 6.3 12.7 19.6 18.4 15.0 11.4 17.7 11.9 4.6 11.6 22.9 6.5 8.5 8.5 13.0 12.6 11.0 14.7 14.4 6.9 5.5 18.5 11.8 12.5 18.2 7.2 17.0 10.6 15.4 16.4 9.7 8.6 17.3 8.3 16.8 9.3 6.7 11.5 13.0 7.3 8.5 9.4 15.0 5.1 14.3 6.3 5.8 9.0 9.1 4.0 3.6 0.6 1.7 4.5 5.4 1.6 6.4 11.0 3.6 2.0 13.0 11.6 2.4 4.5 1.9 4.8 5.1 7.5 3.3 1.5 8.1 4.9 13.0 6.1 9.5 4.7 5.1 2.9 1.1 11.2 1.3 5.6 0.9 6.1 3.5 7.0 2.9 7.7 2.3 5.5 10.1 7.8 1.4 10.0 4.4 2.8 2.5 8.5 11.9 2.8 7.1 5.1 8.3 5.8 9.9 6.8 3.5 6.1 7.6 8.3 15.1 3.6 4.2 5.8 13.9 9.7 1.7 6.6 4.8 1.3 0.1 0.8 0.6 3.7 1.3 4.7 2.8 3.5 1.7 2.7 4.0 5.4 2.8 0.3 4.5 1.7 3.6 3.2 1.6 11.6 17.4 19.6 18.4 12.6 11.0 18.5 11.8 15.4 15.0 FANCL "FAAP43, FLJ10335, PHF9, Pog" ENSG00000115392 "Fanconi anemia complementation group L" Q9NW38 2 58159243-58241372 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 62.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033842, HPA036685, HPA036686" Supported Approved "Nuclear bodies,Vesicles" "Nuclear bodies" Vesicles "CAB033842: AB_1122766, HPA036685: AB_10672474, HPA036686: AB_10670844" "unprognostic (3.02e-1)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-3)" "unprognostic (6.24e-2)" "unprognostic (2.92e-2)" "prognostic unfavourable (2.81e-7)" "unprognostic (4.71e-2)" "unprognostic (2.63e-2)" "unprognostic (1.31e-2)" "unprognostic (3.50e-1)" "unprognostic (1.17e-2)" "prognostic unfavourable (1.12e-7)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (9.08e-3)" "prognostic favourable (7.80e-5)" 6.3 29.2 16.0 11.2 22.9 10.6 16.2 7.1 18.1 11.6 9.6 30.7 7.9 9.2 16.6 15.7 8.6 11.7 9.8 10.2 17.0 23.5 7.1 16.7 7.7 10.9 25.0 15.2 21.3 10.8 16.8 62.5 10.0 33.5 11.6 12.4 13.7 14.8 9.1 6.5 14.4 10.1 11.3 23.4 12.0 10.5 14.7 28.2 8.6 14.2 6.9 12.0 10.1 12.7 10.8 7.1 5.6 6.9 8.8 5.5 2.7 18.4 13.5 27.6 13.5 4.9 6.5 14.7 13.6 8.5 13.5 17.6 11.9 23.3 12.8 17.7 4.4 10.8 15.3 10.3 22.6 30.0 24.2 21.0 19.0 16.1 5.3 20.2 11.6 4.8 4.9 9.8 3.9 10.5 19.5 11.7 9.1 9.4 7.1 25.1 29.8 2.8 13.5 20.9 10.0 11.8 18.3 31.3 15.7 19.4 8.0 12.7 7.3 13.6 6.2 12.1 18.2 8.8 14.9 12.1 7.6 7.5 25.7 13.7 18.3 2.7 3.7 5.6 4.9 6.9 3.8 10.8 4.1 5.4 7.1 10.0 1.4 3.1 1.1 8.8 4.9 6.5 5.5 2.7 16.0 22.9 7.1 18.1 17.0 23.5 25.0 15.2 33.5 28.2 FANCM "FAAP250, KIAA1596" ENSG00000187790 "Fanconi anemia complementation group M" Q8IYD8 14 45135940-45200890 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Disease mutation, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055144 Supported Nucleoplasm Nucleoplasm "HPA055144: " "unprognostic (8.40e-2)" "unprognostic (6.70e-2)" "unprognostic (3.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.15e-1)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (1.18e-1)" "unprognostic (1.57e-2)" "unprognostic (8.52e-2)" "unprognostic (1.14e-1)" "unprognostic (1.23e-2)" "unprognostic (7.55e-2)" "unprognostic (2.90e-1)" "unprognostic (1.71e-1)" "unprognostic (8.94e-2)" "unprognostic (1.13e-2)" 4.7 3.9 3.9 4.4 8.4 9.8 5.7 8.2 7.9 5.7 3.5 4.9 4.9 2.6 6.7 4.8 4.5 4.2 3.7 3.8 3.4 3.3 4.1 3.1 3.3 6.6 3.2 3.6 6.2 3.3 4.5 4.5 4.4 9.3 3.5 3.8 4.8 4.1 4.8 4.2 5.2 3.5 3.8 3.4 8.9 3.2 15.4 4.2 15.2 3.3 2.9 6.4 3.8 4.3 6.7 3.2 7.6 3.6 2.0 4.1 1.1 7.7 6.7 8.0 7.5 6.4 4.0 6.5 10.2 3.9 8.0 10.4 10.9 6.0 10.3 5.8 2.4 10.5 9.4 4.3 11.0 7.5 5.2 4.7 7.6 6.0 1.1 12.2 6.0 2.2 1.6 8.1 5.1 6.8 8.5 9.0 6.7 7.7 9.0 8.8 3.2 11.5 8.4 12.5 4.7 3.3 5.5 7.3 1.9 9.0 7.4 3.8 8.0 5.7 5.4 11.7 11.0 10.7 7.7 4.6 8.2 10.2 2.3 7.6 7.0 7.6 1.3 4.6 4.0 3.6 2.2 6.7 2.5 1.5 1.0 4.2 4.1 3.5 2.1 2.0 1.7 3.2 1.7 1.1 3.9 8.4 8.2 7.9 3.4 3.3 3.2 3.6 9.3 4.2 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 30.0" "Cell line enhanced" "Detected in some" "ASC diff: 47.0;ASC TERT1: 49.9;BJ hTERT+: 39.4;TIME: 19.7;U-138 MG: 40.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059739 Uncertain "Secreted to blood" 34000000 "HPA059739: " "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavourable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 19.8 0.7 2.6 3.2 1.2 0.0 7.5 0.6 3.7 17.6 4.5 0.4 4.0 0.1 30.0 13.7 4.1 5.1 14.9 5.2 3.1 0.9 2.0 0.9 4.7 0.8 2.6 1.2 4.1 2.3 0.5 1.0 17.0 1.9 4.1 1.5 2.4 5.3 3.9 8.1 2.9 1.4 17.9 2.2 0.9 1.7 9.8 3.4 0.0 3.5 9.0 0.8 12.4 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.0 49.9 0.0 19.2 39.4 4.0 6.1 0.0 0.0 0.0 0.1 7.3 0.0 0.0 1.2 1.9 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.0 16.1 0.3 6.7 1.2 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 2.0 0.0 0.0 19.7 40.1 0.8 9.7 0.0 0.0 0.0 0.0 9.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.2 0.6 3.7 3.1 0.9 2.6 1.2 1.9 3.4 FAR1 "FLJ22728, MLSTD2, SDR10E1" ENSG00000197601 "Fatty acyl-CoA reductase 1" Q8WVX9 11 13668670-13732346 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Cataract, Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017322 Approved Supported Peroxisomes Peroxisomes "HPA017322: AB_1848424" "unprognostic (3.96e-2)" "unprognostic (1.92e-1)" "prognostic favourable (2.27e-4)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (4.62e-2)" "unprognostic (3.66e-1)" "unprognostic (3.30e-1)" "unprognostic (2.79e-1)" "unprognostic (3.60e-2)" "unprognostic (2.59e-2)" "unprognostic (1.84e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (2.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-3)" 16.3 11.1 19.0 14.2 28.2 42.7 13.7 24.4 24.0 17.3 20.9 33.8 11.1 24.7 17.4 17.1 38.1 12.7 9.2 13.9 20.4 16.1 9.7 3.3 13.9 12.2 32.8 24.0 16.7 15.8 25.1 16.5 15.8 30.0 14.1 25.1 10.0 14.6 10.9 11.4 8.0 13.4 20.2 47.8 13.9 39.4 12.8 32.2 13.2 13.2 17.2 15.0 16.7 22.1 2.8 15.8 21.8 13.7 5.0 4.5 4.0 26.9 17.6 17.5 13.6 16.7 19.3 9.5 24.2 9.7 17.9 19.0 18.5 23.3 34.7 10.8 19.2 29.5 25.7 24.4 27.5 10.2 20.9 14.8 16.1 0.1 16.1 29.7 12.0 14.6 25.2 12.9 38.8 17.4 23.1 10.4 14.6 13.6 22.0 8.9 9.1 25.6 19.4 22.3 9.7 17.3 43.9 13.5 9.8 22.9 21.8 11.8 13.4 18.6 21.6 24.7 21.1 22.6 20.1 5.8 19.7 29.5 15.7 9.1 14.9 4.6 13.7 15.0 4.5 11.9 3.1 2.1 2.2 3.8 15.8 2.8 2.0 3.4 21.8 5.0 9.4 2.4 2.8 4.0 19.0 28.2 24.4 24.0 20.4 16.1 32.8 24.0 30.0 32.2 FAR2 "FLJ10462, MLSTD1, SDR10E2" ENSG00000064763 "Fatty acyl-CoA reductase 2" Q96K12 12 29149103-29340980 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 25.8;HUVEC TERT2: 30.2;NB-4: 25.9;SK-BR-3: 31.9;TIME: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 23.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015884 Approved Approved "Nucleoli,Golgi apparatus" "Golgi apparatus" Nucleoli "HPA015884: AB_1853998" "unprognostic (6.32e-2)" "unprognostic (2.40e-2)" "unprognostic (1.50e-3)" "unprognostic (3.33e-3)" "unprognostic (2.41e-1)" "unprognostic (4.13e-3)" "unprognostic (4.30e-2)" "unprognostic (1.18e-1)" "unprognostic (3.11e-2)" "unprognostic (6.37e-2)" "unprognostic (5.70e-3)" "unprognostic (1.92e-1)" "prognostic unfavourable (4.93e-4)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.33e-1)" "unprognostic (5.22e-3)" 9.4 7.2 9.8 6.9 17.4 12.0 7.6 5.1 18.2 4.6 25.7 3.2 6.1 13.3 6.2 29.4 6.0 3.7 4.2 5.4 12.8 10.9 4.0 3.1 8.6 6.7 9.4 10.4 2.1 2.6 1.0 2.9 19.2 6.6 2.8 22.3 4.1 4.8 1.7 4.5 8.7 14.0 6.0 5.1 12.3 3.7 8.4 5.9 7.2 3.5 4.5 2.3 6.6 4.3 0.9 4.0 23.7 11.5 1.8 7.6 4.4 0.9 1.7 1.7 0.4 2.5 9.9 0.7 7.5 8.8 2.1 2.0 2.9 10.1 1.3 2.0 1.0 0.5 4.6 0.0 0.5 0.6 11.5 25.8 4.1 0.9 5.3 10.3 8.6 2.8 0.0 3.2 4.0 30.2 2.2 1.0 0.3 0.3 6.6 25.9 7.0 19.7 5.5 2.9 1.1 9.3 2.6 3.0 2.7 1.7 31.9 12.7 1.5 9.7 24.5 5.6 1.7 2.0 3.3 1.6 1.6 0.6 8.9 13.6 4.8 1.3 11.5 23.7 2.7 6.9 1.8 0.9 4.5 3.2 4.0 0.7 1.5 1.7 20.7 1.8 3.7 1.5 7.6 4.4 9.8 17.4 5.1 18.2 12.8 10.9 9.4 10.4 6.6 5.9 FARS2 "dJ236A3.1, FARS1" ENSG00000145982 "Phenylalanyl-tRNA synthetase 2, mitochondrial" O95363 6 5261044-5771580 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018148, HPA028836" Approved Uncertain "Plasma membrane" "Plasma membrane" "HPA018148: AB_1848426, HPA028836: AB_10601377" "unprognostic (2.73e-1)" "unprognostic (4.08e-3)" "prognostic favourable (5.14e-4)" "unprognostic (2.68e-1)" "unprognostic (1.94e-2)" "unprognostic (5.34e-3)" "unprognostic (1.82e-1)" "unprognostic (4.31e-3)" "unprognostic (7.18e-2)" "unprognostic (1.02e-2)" "unprognostic (8.91e-2)" "unprognostic (2.50e-1)" "prognostic favourable (1.24e-6)" "unprognostic (2.81e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" 14.2 19.0 10.6 16.5 14.5 13.2 14.8 16.5 18.8 14.7 13.5 16.4 13.4 9.6 15.3 12.7 13.7 19.8 11.6 19.0 10.5 9.0 18.4 18.5 13.0 21.8 8.9 15.0 11.7 14.0 18.9 29.2 11.4 10.6 12.2 15.2 19.3 15.3 13.5 22.8 15.4 13.0 13.2 8.5 15.0 13.9 15.4 11.0 20.6 19.7 16.0 22.0 13.1 12.9 13.9 16.8 3.2 10.3 14.9 17.5 10.9 8.2 7.9 8.5 9.1 10.6 12.8 7.0 9.1 10.7 11.8 11.6 10.7 6.3 11.6 14.2 8.7 8.2 10.9 14.6 12.4 34.6 7.2 4.6 7.0 9.2 5.5 11.1 6.9 10.1 14.5 13.5 9.6 14.2 13.6 2.7 8.6 8.4 11.8 12.2 5.2 7.7 11.8 10.6 22.7 11.3 9.8 14.6 7.3 8.3 6.7 10.2 13.4 12.0 8.0 12.9 5.9 7.5 11.6 5.6 19.3 6.3 7.1 6.5 15.9 0.1 9.4 3.2 15.6 10.3 13.9 13.9 14.1 14.5 16.8 11.3 15.6 15.5 0.7 14.9 7.3 9.9 17.5 10.9 10.6 14.5 16.5 18.8 10.5 9.0 8.9 15.0 10.6 11.0 FARSA "CML33, FARSL, FARSLA" ENSG00000179115 "Phenylalanyl-tRNA synthetase alpha subunit" Q9Y285 19 12922479-12934037 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001911 Approved Supported Cytosol 11000 Cytosol "HPA001911: AB_1848427" "unprognostic (1.52e-1)" "prognostic favourable (8.23e-4)" "unprognostic (2.71e-1)" "prognostic unfavourable (9.22e-4)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (4.93e-3)" "unprognostic (5.76e-2)" "unprognostic (2.86e-1)" "unprognostic (1.24e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (1.45e-3)" "prognostic favourable (8.32e-4)" "unprognostic (2.59e-1)" "unprognostic (8.25e-2)" "unprognostic (1.84e-2)" 18.0 20.7 24.8 23.6 29.5 23.5 15.4 24.6 49.2 17.7 24.0 18.3 14.9 22.1 16.1 13.1 26.6 21.2 16.3 24.9 23.9 30.1 23.0 39.6 13.4 27.6 25.6 28.1 19.1 26.7 17.8 21.0 22.9 29.1 18.5 15.0 14.8 25.1 20.4 33.3 27.8 18.8 15.3 17.2 21.2 18.9 17.1 18.6 32.7 24.4 15.2 22.0 19.5 15.2 34.7 42.2 28.9 41.2 38.3 40.2 39.7 29.1 27.6 11.1 23.8 7.7 7.3 20.0 21.0 13.6 30.1 23.7 33.7 12.4 32.2 33.8 11.8 22.4 27.0 24.0 11.0 18.9 40.7 25.3 24.3 26.7 25.0 48.7 33.4 10.0 17.7 23.2 18.7 16.3 38.1 6.8 12.6 39.1 57.8 60.7 34.6 46.9 30.0 11.5 41.4 15.8 17.2 34.8 31.9 14.1 24.4 14.9 19.2 29.7 15.6 24.5 10.8 37.2 39.0 45.2 38.5 33.5 22.2 44.1 25.2 17.3 39.2 28.9 32.5 41.2 40.2 31.9 32.0 30.2 42.2 34.7 32.9 31.2 2.5 38.3 30.4 34.1 29.4 39.7 24.8 29.5 24.6 49.2 23.9 30.1 25.6 28.1 29.1 18.6 FARSB "FARSLB, FRSB, PheHB" ENSG00000116120 "Phenylalanyl-tRNA synthetase beta subunit" Q9NSD9 2 222570536-222656337 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036677, HPA036678, HPA061398" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA036677: , HPA036678: AB_10673504, HPA061398: " "unprognostic (9.95e-3)" "unprognostic (1.86e-3)" "unprognostic (7.02e-2)" "unprognostic (7.42e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "prognostic unfavourable (6.45e-10)" "unprognostic (8.89e-3)" "unprognostic (4.51e-2)" "unprognostic (3.63e-2)" "unprognostic (5.25e-3)" "unprognostic (6.25e-2)" "prognostic unfavourable (3.21e-5)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "prognostic unfavourable (1.25e-4)" 15.7 10.8 11.9 12.6 23.5 11.5 16.0 15.1 28.5 11.6 17.3 13.7 5.9 15.9 14.2 11.7 19.1 10.8 7.2 13.4 13.7 15.1 11.7 18.3 9.0 12.0 11.6 18.0 16.7 18.6 15.0 15.7 8.8 29.4 11.2 20.7 9.6 12.3 11.5 33.2 14.1 11.5 14.9 9.7 10.3 13.9 15.6 11.2 15.6 11.9 17.1 14.2 11.8 12.0 16.3 16.0 1.2 11.4 18.5 20.0 14.6 22.0 13.0 15.1 19.7 13.8 19.9 23.3 22.5 14.2 22.2 18.2 32.8 12.2 10.8 17.1 16.4 18.6 29.1 25.2 32.8 16.2 15.1 24.8 14.7 20.9 21.6 36.1 10.3 13.3 19.8 25.4 39.0 21.0 37.3 22.3 27.0 20.6 21.6 20.4 19.3 16.2 21.3 36.4 35.0 18.2 14.4 24.6 8.0 9.4 16.5 19.4 15.3 15.2 11.4 19.1 15.7 27.3 27.1 10.7 10.7 39.5 14.9 24.3 19.9 0.2 8.5 1.2 11.4 10.3 16.8 16.3 15.4 14.0 16.0 14.0 20.0 17.2 0.9 18.5 11.4 8.0 13.3 14.6 11.9 23.5 15.1 28.5 13.7 15.1 11.6 18.0 29.4 11.2 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078333-82098332 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 147.6" "Cell line enhanced" "Detected in many" "SK-BR-3: 152.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" 1600000 "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavourable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavourable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 147.6 7.8 8.2 14.2 11.5 11.1 57.5 19.1 23.0 6.6 27.7 17.0 14.1 8.2 4.7 14.2 17.1 4.3 19.4 6.3 7.9 6.7 3.7 30.8 26.8 9.8 7.3 11.5 6.4 10.4 6.7 15.3 8.4 21.7 28.8 3.4 7.6 16.9 10.8 7.5 17.2 6.5 4.6 8.4 5.1 11.9 6.6 8.8 1.9 5.1 10.7 5.4 8.0 6.6 0.5 1.4 0.0 0.8 0.2 1.9 0.8 23.1 24.3 11.3 7.8 18.3 12.4 24.2 4.6 6.0 4.9 9.0 25.4 15.8 7.7 3.8 3.5 19.4 10.9 21.3 0.9 3.6 47.4 16.0 18.2 33.9 5.2 8.6 2.4 11.9 5.6 12.5 2.9 5.5 24.1 6.9 1.7 40.1 9.4 13.7 21.9 14.2 8.3 6.4 15.3 5.5 29.7 28.1 15.6 6.8 152.8 12.4 27.2 16.5 9.6 7.2 14.8 5.9 11.0 9.3 2.0 8.0 4.3 9.4 10.6 0.0 0.8 0.0 1.2 0.5 0.7 0.5 1.9 1.4 1.4 0.2 0.7 0.6 0.0 0.2 0.4 1.1 0.6 0.8 8.2 11.5 19.1 23.0 7.9 6.7 7.3 11.5 21.7 8.8 FASTK FAST ENSG00000164896 "Fas activated serine/threonine kinase" Q14296 7 151076593-151080866 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031621, CAB032539" Approved Approved "Nuclear speckles,Mitochondria" Mitochondria "Nuclear speckles" "CAB032539: AB_2101115, HPA031621: AB_10611966" "unprognostic (7.67e-2)" "unprognostic (6.41e-3)" "prognostic unfavourable (4.73e-4)" "unprognostic (2.60e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-3)" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (4.66e-2)" "prognostic favourable (3.99e-4)" "unprognostic (3.49e-2)" "unprognostic (2.79e-2)" "unprognostic (4.12e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (8.17e-2)" 13.8 16.8 18.8 15.7 19.0 6.4 10.2 19.0 26.4 18.0 20.6 13.4 20.3 21.2 12.4 14.6 20.3 16.7 16.8 35.7 17.6 12.9 17.7 25.6 9.5 10.4 12.0 15.0 14.4 20.7 20.2 21.8 18.5 12.0 16.8 10.6 14.0 21.7 17.9 89.5 14.4 25.8 11.3 9.2 14.9 14.8 10.6 10.9 11.2 16.8 28.1 16.9 17.4 11.8 15.4 26.0 19.7 22.3 13.1 19.0 14.5 15.7 18.4 5.9 14.1 22.0 9.9 9.8 12.7 17.3 10.8 13.0 12.7 13.7 3.7 17.3 17.1 10.3 5.6 15.2 2.9 10.8 10.1 4.6 4.6 10.8 27.9 3.2 10.4 13.0 22.3 12.5 9.2 12.7 6.7 7.9 12.5 31.7 7.7 9.2 9.9 21.7 5.1 7.1 11.8 14.7 10.9 7.0 7.3 16.7 26.0 16.9 14.0 12.6 10.4 13.8 3.0 12.9 11.2 21.2 12.9 2.4 27.5 7.2 15.8 10.5 22.3 19.7 16.4 21.7 17.1 13.7 17.3 16.9 19.4 15.4 19.0 16.3 4.8 13.1 20.8 26.0 18.7 14.5 18.8 19.0 19.0 26.4 17.6 12.9 12.0 15.0 12.0 10.9 FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 248.1;lung: 87.8" "Cell line enhanced" "Detected in some" "HaCaT: 20.1;MCF7: 62.8;RT4: 41.2;SK-BR-3: 12.0;U-698: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "eosinophil: 73.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA005857, HPA012513, CAB033869" Enhanced Uncertain Mitochondria 23000000 Mitochondria "CAB033869: AB_1121520, HPA005857: AB_1848445, HPA012513: AB_1848446" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.40e-1)" "prognostic favourable (5.16e-4)" "unprognostic (1.13e-2)" "unprognostic (1.37e-1)" "prognostic favourable (1.79e-4)" "unprognostic (6.94e-3)" "unprognostic (4.52e-2)" "unprognostic (7.79e-2)" "unprognostic (7.59e-2)" "unprognostic (1.12e-1)" "prognostic favourable (6.86e-7)" "unprognostic (6.91e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "prognostic favourable (1.64e-5)" 19.3 5.8 0.6 2.3 0.9 1.1 7.0 0.4 0.8 2.2 48.8 0.7 17.6 40.7 0.6 2.5 0.7 0.9 9.7 1.3 0.8 0.5 34.6 248.1 87.8 8.9 0.9 0.7 1.0 8.1 17.1 1.9 1.0 1.0 6.4 3.0 1.5 9.1 17.7 0.5 1.7 60.4 3.1 1.2 2.8 10.4 1.0 0.8 0.5 4.3 1.0 1.1 22.4 9.6 0.6 17.1 73.5 30.7 2.8 3.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.1 20.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.3 5.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 62.8 0.0 1.1 0.2 2.2 0.0 0.2 0.4 0.0 41.2 0.2 1.2 0.1 12.0 0.0 7.2 1.7 0.0 0.0 0.2 0.2 0.0 0.0 0.1 29.9 0.0 0.3 0.0 10.6 13.0 73.5 1.5 30.7 2.3 0.6 0.9 0.9 17.1 0.6 3.3 1.6 2.3 2.8 16.3 6.1 0.4 5.2 0.6 0.9 0.4 0.8 0.8 0.5 0.9 0.7 1.0 0.8 FBP2 ENSG00000130957 "Fructose-bisphosphatase 2" O00757 9 94558720-94593793 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 33.7;skeletal muscle: 134.7;tongue: 45.6" "Cell line enhanced" "Detected in some" "BEWO: 7.2;CACO-2: 3.7;HMC-1: 4.0;MCF7: 5.3;PC-3: 3.7;SiHa: 5.0" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 36 "pons and medulla: 33.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA012513, HPA055286, HPA077371" Enhanced Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA012513: AB_1848446, HPA055286: , HPA077371: " "unprognostic (3.88e-2)" "unprognostic (3.54e-4)" "unprognostic (2.38e-1)" "unprognostic (6.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-2)" "unprognostic (9.40e-4)" "unprognostic (3.95e-3)" "unprognostic (5.11e-2)" "unprognostic (2.39e-2)" "unprognostic (4.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.48e-4)" 2.0 0.4 0.1 0.0 0.1 0.0 0.2 0.1 0.9 0.1 0.1 3.8 4.4 1.0 0.1 1.0 1.6 0.1 0.0 0.1 0.7 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.1 1.2 4.1 0.1 0.0 33.7 0.2 0.0 5.0 1.4 1.8 134.7 0.1 0.1 0.1 0.2 0.1 9.0 0.4 0.0 0.0 0.2 45.6 2.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.3 0.0 2.5 0.0 0.0 7.2 0.0 0.0 0.1 0.0 3.7 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 1.9 2.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 2.4 0.6 0.1 5.0 1.2 0.0 0.4 0.1 0.0 0.0 2.3 2.2 0.0 0.0 0.1 1.0 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.7 0.1 0.1 0.0 33.7 0.0 FBXO18 "FBH1, Fbx18, FLJ14590" ENSG00000134452 "F-box protein, helicase, 18" Q8NFZ0 10 5890203-5937594 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002844 Supported "HPA002844: AB_1078829" "unprognostic (3.14e-2)" "unprognostic (1.55e-1)" "unprognostic (6.35e-3)" "unprognostic (4.42e-2)" "unprognostic (3.37e-2)" "unprognostic (8.98e-3)" "prognostic unfavourable (7.73e-7)" "unprognostic (1.89e-1)" "unprognostic (2.42e-1)" "unprognostic (3.37e-2)" "unprognostic (1.56e-2)" "unprognostic (2.23e-1)" "unprognostic (6.91e-3)" "unprognostic (3.69e-1)" "unprognostic (4.35e-2)" "unprognostic (1.24e-1)" "unprognostic (9.54e-2)" 21.3 30.6 21.0 22.4 28.2 18.8 32.7 23.0 21.8 23.5 21.9 18.1 26.3 21.7 30.6 21.2 23.8 28.7 22.8 35.1 21.0 13.4 20.4 23.2 22.5 24.2 19.4 18.0 27.5 26.2 23.3 24.5 23.6 22.5 23.9 22.1 23.1 21.0 24.8 23.6 26.2 23.4 27.5 13.5 29.7 22.4 27.1 20.1 36.8 22.8 14.9 23.3 23.8 33.8 6.1 6.1 4.8 3.2 7.2 9.2 2.5 14.4 15.8 14.9 16.3 34.4 22.8 13.4 16.8 11.6 16.7 18.8 18.7 13.3 13.6 11.1 24.4 21.7 20.1 17.9 15.2 14.7 14.8 13.0 12.5 15.9 23.7 6.4 12.7 28.5 17.4 21.1 9.4 28.2 22.9 14.4 17.6 22.0 15.5 9.5 6.8 9.0 17.2 7.1 22.6 16.3 11.8 8.5 12.8 17.2 15.7 23.3 16.0 13.1 17.6 10.7 12.0 28.2 12.9 14.8 11.6 7.6 14.4 9.5 7.4 0.0 3.2 4.8 3.2 2.5 2.1 4.9 3.3 4.1 3.0 6.1 4.0 2.9 2.1 7.2 1.9 6.1 9.2 2.5 21.0 28.2 23.0 21.8 21.0 13.4 19.4 18.0 22.5 20.1 FDFT1 ENSG00000079459 "Farnesyl-diphosphate farnesyltransferase 1" P37268 8 11795573-11839309 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 78.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008874 Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA008874: AB_1078844" "unprognostic (2.33e-1)" "unprognostic (2.60e-1)" "prognostic favourable (4.92e-5)" "unprognostic (1.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.71e-1)" "unprognostic (8.10e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (2.45e-1)" "unprognostic (2.31e-3)" "unprognostic (2.57e-1)" "prognostic favourable (6.59e-9)" "unprognostic (2.28e-1)" "unprognostic (4.06e-2)" "unprognostic (3.86e-1)" "unprognostic (2.06e-1)" 20.8 44.3 26.3 22.7 27.7 30.6 57.5 19.5 43.6 27.6 41.7 45.9 20.0 44.6 26.9 29.1 59.4 27.5 19.9 27.1 29.8 32.1 24.9 45.9 30.7 23.4 36.2 34.4 22.9 18.0 17.1 18.2 22.1 47.4 38.8 32.9 32.4 46.5 20.6 71.2 38.4 30.2 18.0 56.5 18.4 35.4 41.3 40.5 25.9 24.7 32.2 25.4 25.8 34.2 44.0 30.5 42.2 19.6 22.6 31.0 29.0 21.6 10.5 47.1 18.8 10.2 17.5 14.3 8.5 14.5 9.0 18.7 14.7 26.8 30.1 4.2 8.5 18.0 23.3 71.0 7.3 5.0 24.9 14.1 8.0 35.0 21.7 7.3 9.9 15.7 18.0 20.1 10.0 11.3 20.3 39.7 8.8 14.1 25.7 17.4 41.2 6.2 15.8 10.9 61.8 41.8 78.8 15.1 9.4 7.4 12.6 21.3 20.7 21.3 14.1 4.2 10.5 1.9 5.3 8.2 20.7 32.8 7.4 24.8 12.4 42.2 19.6 22.6 21.6 17.2 20.8 44.0 22.7 21.2 30.5 35.3 21.5 20.3 18.6 22.6 11.7 22.7 31.0 29.0 26.3 27.7 19.5 43.6 29.8 32.1 36.2 34.4 47.4 40.5 FDPS ENSG00000160752 "Farnesyl diphosphate synthase" P14324 1 155308748-155320666 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Host-virus interaction, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028200 Approved Approved Nucleoplasm,Cytosol 2000000 Cytosol Nucleoplasm "HPA028200: AB_10612109" "unprognostic (1.23e-1)" "unprognostic (8.46e-3)" "unprognostic (2.47e-2)" "unprognostic (6.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.84e-2)" "prognostic unfavourable (7.35e-4)" "unprognostic (4.21e-2)" "unprognostic (6.78e-3)" "unprognostic (1.64e-3)" "unprognostic (7.19e-2)" "unprognostic (2.25e-2)" "unprognostic (1.11e-2)" "unprognostic (8.25e-2)" "unprognostic (2.07e-1)" "unprognostic (5.65e-2)" "unprognostic (8.44e-2)" 21.0 57.8 19.3 17.6 26.5 16.5 19.8 12.8 32.2 19.0 25.0 22.6 14.5 45.9 18.0 21.7 41.4 16.7 18.8 19.6 18.6 23.4 23.7 100.8 25.7 19.2 19.5 24.3 15.2 27.5 15.6 12.3 20.2 47.3 16.5 29.7 20.5 29.2 12.9 15.7 29.3 32.3 18.9 23.0 17.7 23.4 15.1 16.5 25.1 19.5 41.7 27.3 13.7 20.8 41.1 39.7 49.4 37.1 45.3 45.5 48.3 35.6 19.4 71.3 25.7 16.7 61.3 25.4 17.0 33.7 27.2 44.3 31.4 84.9 27.2 41.4 14.9 39.8 42.4 147.8 25.5 14.8 30.4 15.8 34.6 37.8 27.5 25.5 18.1 43.6 23.4 43.2 21.7 47.3 28.1 73.3 28.3 38.3 32.6 24.8 42.8 28.4 28.2 30.9 75.4 71.6 23.8 27.7 23.7 17.5 31.9 29.4 23.0 69.4 34.4 15.2 18.7 9.4 31.1 31.1 23.9 48.5 14.8 27.2 23.9 30.5 36.0 49.4 39.4 37.1 35.0 41.1 34.8 39.8 39.7 34.2 31.5 39.3 16.5 45.3 27.2 31.4 45.5 48.3 19.3 26.5 12.8 32.2 18.6 23.4 19.5 24.3 47.3 16.5 FDXR ADXR ENSG00000161513 "Ferredoxin reductase" P22570 17 74862497-74873031 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Oxidoreductase "Deafness, Disease mutation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 93.9" "Cell line enhanced" "Detected in many" "BEWO: 29.5;Hep G2: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008597, CAB009818, HPA044393, HPA053673" Enhanced Enhanced Mitochondria Mitochondria "CAB008597: AB_1615557, CAB009818: AB_2102601, HPA044393: AB_2678927, HPA053673: AB_2682225" "unprognostic (2.69e-2)" "unprognostic (1.17e-3)" "unprognostic (7.51e-2)" "prognostic favourable (2.38e-4)" "unprognostic (3.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" "unprognostic (1.68e-2)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (6.30e-2)" "unprognostic (1.42e-2)" "unprognostic (1.19e-2)" "unprognostic (4.50e-2)" "unprognostic (4.03e-2)" "unprognostic (2.13e-1)" 1.7 93.9 2.6 2.1 3.1 1.3 1.8 8.4 2.7 2.1 4.6 3.2 6.4 2.6 2.6 23.8 8.7 6.6 6.1 1.9 3.4 1.7 2.7 4.1 4.4 1.7 2.9 3.5 7.1 3.9 2.3 1.5 2.6 3.6 3.3 2.1 0.9 5.3 4.2 7.9 5.6 2.5 2.0 4.4 9.7 2.2 32.1 3.0 3.9 2.0 7.7 3.7 3.0 3.0 5.4 7.4 4.8 6.4 10.0 15.2 5.6 3.9 21.1 3.1 3.5 2.3 3.0 29.5 4.7 5.2 2.8 5.7 5.9 3.5 9.4 0.8 2.0 8.1 2.3 5.9 0.8 8.9 4.9 7.1 3.5 54.0 6.4 1.5 25.0 9.9 6.7 2.9 1.0 14.4 11.3 1.5 4.3 16.7 6.1 3.3 1.7 4.6 3.3 5.3 5.0 2.3 6.7 1.7 4.0 3.2 7.1 3.4 15.4 1.5 6.7 1.9 17.6 3.1 2.3 4.4 0.7 2.0 5.3 2.4 6.6 1.8 6.4 4.8 6.2 4.3 5.3 5.4 5.6 7.3 7.4 2.8 4.9 6.1 2.1 10.0 3.2 1.4 15.2 5.6 2.6 3.1 8.4 2.7 3.4 1.7 2.9 3.5 3.6 3.0 FECH ENSG00000066926 Ferrochelatase P22830 18 57548283-57586772 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 87.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044100, HPA048177" Approved "HPA044100: , HPA048177: " "unprognostic (2.30e-1)" "unprognostic (3.17e-2)" "unprognostic (4.59e-3)" "unprognostic (6.85e-2)" "unprognostic (7.60e-2)" "unprognostic (1.08e-1)" "unprognostic (3.86e-2)" "unprognostic (3.34e-2)" "unprognostic (2.85e-2)" "unprognostic (2.43e-1)" "unprognostic (1.92e-1)" "unprognostic (2.36e-1)" "prognostic favourable (2.38e-10)" "unprognostic (1.10e-1)" "unprognostic (8.30e-2)" "unprognostic (4.05e-3)" "unprognostic (3.58e-2)" 10.0 18.0 9.9 6.5 14.1 87.9 9.9 7.9 17.4 7.9 9.5 23.1 8.0 7.6 10.5 7.9 13.6 8.5 6.9 17.6 10.4 9.7 28.2 28.3 7.2 9.8 12.0 13.9 9.1 9.5 11.4 8.8 14.8 15.6 14.5 9.3 12.1 10.1 11.1 36.2 8.6 7.2 12.3 11.7 10.6 8.5 5.8 13.1 18.4 11.6 10.8 7.1 12.1 8.8 4.2 12.4 14.9 10.9 13.8 9.3 9.1 7.3 20.0 7.4 11.9 4.7 10.8 13.0 10.5 10.7 15.2 13.6 5.3 6.7 3.3 10.8 14.4 9.4 10.9 8.8 12.3 19.2 11.6 24.3 13.9 11.0 12.1 16.9 44.4 11.2 9.4 9.4 4.3 11.4 34.5 13.9 8.5 8.7 17.6 3.5 5.6 8.7 12.6 10.3 19.8 15.1 13.9 7.4 11.2 13.6 14.6 6.2 13.9 7.1 9.0 5.3 7.0 2.1 7.6 40.6 17.4 7.1 8.6 8.3 8.9 14.0 9.6 14.9 9.3 10.9 6.7 4.2 5.7 8.3 12.4 2.6 4.2 5.9 0.7 13.8 10.2 9.5 5.9 9.1 9.9 14.1 7.9 17.4 10.4 9.7 12.0 13.9 15.6 13.1 FER "PPP1R74, TYK3" ENSG00000151422 "FER tyrosine kinase" P16591 5 108747822-109196841 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007641, CAB022464" Approved Supported Cytosol Cytosol "CAB022464: , HPA007641: AB_1078845" "unprognostic (1.72e-1)" "unprognostic (1.66e-2)" "unprognostic (1.74e-1)" "unprognostic (2.46e-3)" "unprognostic (4.72e-2)" "unprognostic (5.65e-2)" "unprognostic (6.81e-2)" "unprognostic (7.39e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-3)" "unprognostic (7.36e-2)" "unprognostic (8.05e-2)" "prognostic favourable (5.55e-4)" "unprognostic (3.83e-3)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-3)" 13.4 5.7 5.5 6.1 13.4 1.8 5.2 6.0 5.0 9.7 6.7 1.4 16.8 2.5 6.5 19.3 8.2 4.6 5.3 4.6 4.8 4.8 7.2 3.6 12.2 1.9 4.9 2.2 7.2 3.0 18.5 15.9 5.7 3.1 6.8 3.6 5.0 4.5 21.9 5.0 6.6 3.5 7.2 6.2 8.1 4.1 15.9 2.6 3.9 10.2 12.8 2.8 7.7 9.0 10.5 5.4 8.0 5.1 1.2 2.8 1.1 4.6 1.6 5.7 9.0 3.4 5.2 3.6 5.6 5.5 3.3 3.9 9.5 2.9 7.5 3.5 6.7 3.3 3.1 7.0 7.5 3.1 4.2 4.9 7.2 3.4 2.3 2.7 4.2 3.1 3.9 7.9 9.0 4.9 6.1 5.6 4.2 1.3 2.1 0.8 0.8 3.3 1.7 5.5 44.2 3.2 1.6 1.9 2.8 9.2 0.5 6.0 2.2 1.2 7.2 6.4 4.9 3.2 4.4 4.8 7.1 2.9 4.0 0.8 3.0 8.0 5.1 5.4 1.7 3.1 2.8 10.5 1.0 1.8 2.8 3.8 1.6 2.0 0.4 1.2 2.4 5.4 2.1 1.1 5.5 13.4 6.0 4.2 4.8 4.8 4.9 2.2 3.1 2.6 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 60.8;lymphoid tissue: 49.7" "Cell line enhanced" "Detected in many" "HEL: 20.9;HL-60: 18.6;HMC-1: 39.8;NB-4: 24.4;THP-1: 36.6;U-937: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 60.8" "Group enriched" "Detected in many" 4 "dendritic cells: 32.6;granulocytes: 60.8;monocytes: 30.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavourable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 14.9 3.4 4.8 9.7 4.1 38.3 12.7 2.4 5.7 6.8 5.4 3.2 4.7 3.0 7.4 5.6 4.9 7.6 7.3 7.9 4.2 2.2 5.2 11.8 12.7 23.3 3.7 0.9 6.4 3.7 1.8 2.7 8.1 7.2 7.7 2.4 5.3 33.8 6.3 3.4 3.5 5.2 5.4 6.9 49.7 4.3 3.2 4.7 3.1 7.2 4.1 4.5 7.2 9.4 1.1 32.6 60.8 30.5 9.3 0.1 13.8 0.1 0.2 0.3 3.5 1.0 3.1 6.0 0.9 0.0 1.7 1.0 0.8 0.0 2.2 0.1 2.0 0.5 0.6 0.1 0.5 1.1 0.3 20.9 0.0 3.7 2.0 18.6 39.8 3.0 0.0 2.6 0.0 10.5 0.6 0.0 0.0 6.8 0.5 24.4 1.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.0 36.6 8.3 0.0 3.6 0.1 0.0 0.0 2.6 0.8 0.1 15.8 0.8 10.4 30.5 60.8 0.1 17.6 0.0 1.1 0.0 0.0 32.6 0.9 0.0 0.0 20.0 9.3 7.3 12.9 0.0 13.8 4.8 4.1 2.4 5.7 4.2 2.2 3.7 0.9 7.2 4.7 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38411138-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease mutation, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 109.2;BJ hTERT+: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved 120000000 "CAB033614: AB_783377, HPA056402: " "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 41.1 8.6 12.5 14.5 12.2 7.2 39.5 45.0 10.5 36.0 31.5 10.1 11.6 5.5 29.3 20.6 22.9 29.4 32.4 31.7 12.8 10.1 11.8 5.4 18.6 9.7 11.4 14.3 42.0 51.2 11.5 22.3 28.4 20.0 28.2 10.8 35.8 14.0 31.6 12.0 12.9 14.4 52.4 15.6 4.5 16.4 16.4 8.5 11.3 12.6 13.0 9.8 39.6 41.2 1.6 0.7 1.8 1.1 0.8 5.7 0.7 2.4 9.3 40.3 109.2 25.1 17.9 26.6 24.8 49.8 17.3 18.0 6.0 1.4 0.3 6.9 23.8 0.0 19.1 1.2 20.0 6.5 4.2 0.0 1.5 5.9 14.1 5.8 0.1 16.2 0.1 14.0 2.8 16.6 2.2 0.1 8.1 2.8 17.0 1.9 28.4 3.9 15.7 4.2 0.0 8.4 0.0 1.6 3.6 4.4 0.2 1.0 2.2 1.1 10.4 11.3 6.2 31.2 5.9 0.4 0.7 0.0 13.4 0.3 5.9 1.4 1.1 0.4 5.7 0.3 3.9 0.7 2.7 3.7 0.1 1.6 1.5 4.1 1.8 0.8 0.5 0.7 2.2 0.7 12.5 12.2 45.0 10.5 12.8 10.1 11.4 14.3 20.0 8.5 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478334-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.8" "Cell line enhanced" "Detected in some" "AN3-CA: 57.8;BEWO: 19.4;CACO-2: 15.1;HaCaT: 17.4;HAP1: 18.7;NTERA-2: 18.5;T-47d: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 10.8;eosinophil: 4.6" "Lineage enriched" "Detected in single" 35 "granulocytes: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" 500000 "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favourable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favourable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 2.1 8.8 16.4 3.0 30.3 0.0 9.9 15.8 21.3 6.8 14.1 55.7 5.6 4.2 22.0 6.6 10.2 12.5 12.5 1.4 20.6 11.1 11.4 16.1 13.1 1.0 41.2 13.3 7.4 12.8 25.5 2.5 6.2 30.2 11.7 8.7 16.4 23.8 24.3 0.4 45.4 4.7 18.3 74.8 0.5 9.3 2.9 32.1 0.8 23.4 1.6 3.4 6.9 8.5 0.1 0.1 10.8 0.1 0.1 0.3 0.0 2.2 0.1 9.0 57.8 0.0 0.0 19.4 0.1 0.0 0.0 0.0 15.1 0.3 0.0 4.1 0.9 17.4 18.7 4.0 0.0 0.0 4.0 0.0 0.0 0.3 0.4 0.0 3.8 0.0 8.4 0.0 0.2 0.0 0.0 0.0 0.0 3.5 0.0 0.0 18.5 0.0 0.0 0.0 2.2 5.6 4.9 0.1 0.1 0.1 10.6 0.0 15.5 0.0 0.0 0.1 2.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 10.8 0.1 4.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 16.4 30.3 15.8 21.3 20.6 11.1 41.2 13.3 30.2 32.1 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease mutation, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 131.7" "Cell line enhanced" "Detected in many" "CACO-2: 19.1;HaCaT: 14.9;Hep G2: 32.1;NTERA-2: 15.6;RT4: 19.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" 670000 "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: " "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavourable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.5 1.5 24.7 1.7 30.3 1.6 4.2 10.2 22.0 4.1 4.9 15.8 3.4 9.9 1.8 2.7 26.9 2.0 5.0 2.0 21.6 11.7 9.6 7.4 4.5 1.3 17.6 21.5 1.1 23.0 1.2 3.0 5.6 15.1 3.7 3.8 1.7 3.8 9.0 1.7 131.7 7.4 1.3 9.0 2.1 4.9 8.1 10.6 0.1 1.3 8.5 7.3 8.5 10.1 0.1 0.6 0.1 0.1 0.2 0.3 0.0 0.0 1.5 9.0 2.6 0.0 0.1 9.2 1.0 0.1 0.4 0.2 19.1 0.4 0.0 7.6 0.3 14.9 2.6 0.1 0.1 0.1 9.6 5.9 1.5 32.1 0.0 0.0 0.1 0.0 5.0 0.1 0.0 0.0 6.4 0.0 0.0 9.5 0.3 0.2 15.6 0.0 0.5 0.5 0.1 1.3 19.1 2.6 0.7 0.8 1.6 0.0 8.9 1.1 0.4 0.0 0.9 0.2 0.6 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.6 0.1 0.0 24.7 30.3 10.2 22.0 21.6 11.7 17.6 21.5 15.1 10.6 FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086886-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 33.6;kidney: 37.7;liver: 45.3" "Group enriched" "Detected in many" 4 "CACO-2: 42.0;Hep G2: 42.0;RH-30: 67.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "neutrophil: 3.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" 4300000 "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" 0.5 5.7 0.7 14.3 0.6 0.1 1.6 2.6 0.5 2.8 10.4 0.9 0.7 13.5 0.9 4.8 1.6 1.7 33.6 0.7 0.8 0.3 37.7 45.3 25.3 2.5 0.7 1.0 13.6 26.0 0.0 0.7 1.3 0.8 4.0 3.7 2.0 1.6 0.3 4.3 0.5 17.3 1.6 0.8 11.2 5.4 2.9 0.4 0.3 0.8 2.3 0.7 1.9 3.6 1.1 0.9 3.0 1.1 0.4 0.4 0.0 0.7 11.8 0.2 2.9 0.0 0.0 5.8 0.0 0.0 0.0 0.0 42.0 1.6 1.2 5.5 0.0 0.6 2.3 0.4 0.0 0.7 2.8 0.1 0.6 42.0 1.3 0.1 1.0 0.2 0.0 2.1 0.0 0.0 3.9 0.1 0.9 9.6 0.0 0.8 7.1 1.0 1.9 67.6 7.1 5.7 0.1 0.4 0.7 0.4 3.0 1.4 2.9 0.6 0.2 0.0 5.7 0.0 0.1 0.4 0.4 0.7 0.0 0.2 0.5 1.5 1.1 0.4 0.4 0.3 0.3 1.1 0.4 0.0 0.1 0.6 0.4 0.4 3.0 0.4 0.3 0.9 0.2 0.0 0.7 0.6 2.6 0.5 0.8 0.3 0.7 1.0 0.8 0.4 FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635277 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 20.8;blood: 68.0;bone marrow: 73.6;lung: 30.9;lymphoid tissue: 54.3" "Group enriched" "Detected in some" 4 "Daudi: 29.4;U-266/70: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" 20.8 2.6 2.2 23.6 4.5 73.6 5.6 1.1 4.2 2.9 2.8 1.5 4.2 1.6 4.0 2.3 2.2 6.3 5.3 8.5 2.6 2.3 3.0 4.2 30.9 34.1 6.6 1.7 1.9 2.4 0.4 1.2 3.3 4.2 2.5 1.8 2.1 2.9 2.6 4.4 1.7 3.7 6.4 4.8 54.3 2.5 2.6 4.1 1.9 2.9 2.5 7.8 5.1 6.1 13.3 28.9 40.8 68.0 36.3 29.6 55.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 54.6 0.7 2.2 0.0 6.7 0.0 3.1 52.4 32.3 29.6 68.0 1.7 7.7 2.6 13.6 28.9 13.3 1.3 12.8 40.8 36.3 55.6 1.3 0.1 55.0 2.2 4.5 1.1 4.2 2.6 2.3 6.6 1.7 4.2 4.1 FH fumarase ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519761 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 93.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria 2800000 Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favourable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" 14.3 28.1 15.7 10.4 20.2 9.3 13.3 15.7 24.4 10.5 22.7 9.9 16.7 23.2 13.7 10.7 17.7 10.3 9.5 59.0 22.9 13.9 35.0 93.4 9.9 13.3 15.2 19.4 9.4 13.9 25.2 11.4 14.3 18.4 12.3 24.4 10.2 18.4 20.6 65.1 13.4 21.4 14.7 14.4 11.1 17.5 14.0 11.7 13.8 12.3 45.2 13.4 13.4 11.2 16.0 26.4 4.5 18.8 10.4 13.9 8.9 29.2 24.5 23.3 21.0 22.9 27.0 36.9 36.3 28.5 41.0 25.8 35.1 18.3 18.6 24.1 27.8 41.7 35.6 27.0 35.8 21.2 11.5 17.4 26.0 29.9 20.5 40.7 15.9 19.5 16.8 23.0 26.0 25.2 53.0 24.1 29.8 14.6 35.1 27.2 24.7 52.7 29.0 25.5 83.5 39.5 24.9 30.0 25.9 30.6 36.3 23.2 27.6 27.7 24.7 18.4 23.8 32.5 60.5 21.6 23.1 22.6 20.6 46.8 26.4 4.5 12.8 2.7 9.7 18.8 12.6 16.0 11.4 9.0 26.4 14.1 13.9 12.7 0.7 10.4 15.7 13.2 13.2 8.9 15.7 20.2 15.7 24.4 22.9 13.9 15.2 19.4 18.4 11.7 FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad" P49789 3 59749310-61251459 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 11.9;U-266/70: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "naive CD4 T-cell: 38.3" "Lineage enriched" "Detected in all" 14 "T-cells: 38.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favourable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" 6.4 24.0 13.7 8.0 17.5 9.0 12.1 4.7 13.3 7.9 8.0 21.0 12.4 8.2 6.2 9.5 5.1 9.2 13.0 14.9 15.3 13.8 30.9 10.7 5.2 9.3 19.5 9.3 8.9 11.8 16.3 15.2 4.1 14.4 5.8 7.8 14.0 11.4 9.9 11.6 7.0 7.6 9.1 17.1 6.0 8.1 10.5 18.2 3.7 15.6 5.7 6.9 7.3 6.1 1.6 2.4 1.8 1.8 2.6 38.3 4.7 0.0 0.0 1.0 0.0 0.6 0.0 1.6 0.1 0.1 0.0 0.0 1.8 3.0 2.6 0.5 0.1 0.0 10.0 2.1 0.0 1.4 3.4 2.2 1.3 4.1 2.6 5.6 0.1 6.8 4.1 0.1 5.1 0.0 1.6 8.3 0.1 2.5 10.1 4.5 0.8 0.6 7.5 0.0 11.9 11.2 1.3 2.1 2.8 1.0 6.9 6.5 0.4 0.1 0.0 1.2 0.4 0.1 1.5 24.4 7.4 0.0 2.7 0.0 1.4 1.8 1.8 0.2 0.9 1.2 0.5 1.6 6.9 0.7 2.2 1.4 38.3 6.7 0.3 2.6 0.4 2.4 7.4 4.7 13.7 17.5 4.7 13.3 15.3 13.8 19.5 9.3 14.4 18.2 FICD "HIP13, HYPE" ENSG00000198855 "FIC domain containing" Q9BVA6 12 108515185-108525837 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" "Hydrolase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021390, HPA071134" Approved Approved Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA021390: AB_1851340, HPA071134: " "unprognostic (1.00e-1)" "unprognostic (8.76e-2)" "unprognostic (1.76e-2)" "prognostic favourable (4.61e-5)" "unprognostic (6.92e-2)" "unprognostic (2.68e-2)" "unprognostic (5.73e-2)" "unprognostic (2.84e-2)" "unprognostic (8.68e-2)" "unprognostic (2.57e-1)" "unprognostic (3.15e-2)" "unprognostic (1.19e-1)" "unprognostic (7.66e-2)" "unprognostic (1.56e-2)" "unprognostic (6.22e-2)" "unprognostic (3.12e-2)" "unprognostic (3.65e-2)" 4.2 9.6 5.6 6.1 8.2 3.0 4.5 4.0 6.7 8.5 3.8 7.3 10.5 3.9 4.6 15.8 2.3 4.1 4.1 3.5 5.4 5.9 5.2 16.4 5.0 4.9 8.9 5.1 4.8 27.9 4.8 15.3 7.9 6.0 6.1 3.6 10.2 19.7 7.9 2.6 3.4 3.3 4.6 7.5 4.8 5.1 8.5 6.6 5.4 13.6 1.0 6.2 4.1 4.5 5.0 15.2 10.9 5.4 3.1 8.0 1.8 1.9 4.7 1.9 3.8 4.6 3.2 5.3 12.5 6.6 5.9 4.2 2.9 1.9 2.6 4.7 5.9 2.5 2.0 1.4 5.3 4.4 3.1 1.5 3.6 4.1 18.2 2.2 5.6 1.5 3.0 8.3 11.9 4.2 1.0 9.0 5.2 4.3 2.9 2.3 2.1 7.9 1.7 2.6 6.4 2.8 3.7 1.8 1.3 5.6 2.6 6.1 4.2 2.1 4.7 6.1 2.2 10.6 4.8 17.9 2.9 0.9 8.4 1.9 4.2 10.9 2.8 4.2 6.8 4.8 8.0 5.0 5.0 6.2 2.7 3.3 2.9 5.6 5.5 3.1 5.4 15.2 3.1 1.8 5.6 8.2 4.0 6.7 5.4 5.9 8.9 5.1 6.0 6.6 FKBP10 "FKBP6, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FK506 binding protein 10" Q96AY3 17 41812680-41823217 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "NK-cell: 2.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Vesicles "Intracellular and membrane" 5500 Vesicles "HPA051171: , HPA057021: " "unprognostic (8.30e-2)" "prognostic unfavourable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavourable (3.43e-5)" "prognostic unfavourable (4.99e-4)" 16.9 16.5 6.6 13.2 7.2 0.2 14.9 3.4 8.4 43.0 11.5 6.0 15.8 3.8 42.7 39.0 14.0 21.4 28.6 19.2 5.6 3.6 10.3 3.2 16.2 17.1 5.3 6.7 35.5 13.5 24.7 22.7 33.8 5.2 21.3 5.7 17.1 6.5 17.0 9.6 8.8 7.6 27.9 5.5 7.9 8.5 15.1 5.7 1.2 16.9 9.5 8.1 24.4 19.2 0.3 0.0 0.0 0.0 2.0 0.9 0.1 0.0 16.1 14.9 48.7 52.4 61.2 13.1 66.3 66.4 25.0 21.6 8.3 0.6 0.0 0.9 72.0 0.1 8.9 17.7 10.6 4.4 13.3 6.4 18.1 23.8 57.2 0.0 0.0 65.7 0.0 20.5 15.7 21.2 0.2 2.3 20.8 20.9 0.0 0.0 11.6 5.4 1.3 17.5 2.1 4.3 0.0 3.7 13.0 0.1 47.7 22.2 7.5 0.4 24.0 30.2 15.7 20.0 10.1 0.1 0.0 0.0 41.3 0.0 28.7 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.1 6.6 7.2 3.4 5.8 5.6 3.6 5.3 6.7 5.2 5.7 FKBP11 FKBP19 ENSG00000134285 "FK506 binding protein 11" Q9NYL4 12 48921518-48926474 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 175.6;salivary gland: 62.0" "Cell line enhanced" "Detected in many" "HHSteC: 46.2;Karpas-707: 42.0;RPMI-8226: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "MAIT T-cell: 37.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041709 Enhanced Approved Centrosome Centrosome "HPA041709: AB_10794487" "unprognostic (7.45e-3)" "unprognostic (8.62e-2)" "unprognostic (2.40e-1)" "prognostic favourable (7.09e-4)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (3.46e-2)" "unprognostic (1.75e-1)" "unprognostic (7.64e-2)" "unprognostic (3.49e-3)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavourable (0.00e+0)" "unprognostic (2.15e-1)" "unprognostic (4.51e-1)" "unprognostic (2.79e-1)" "unprognostic (1.54e-1)" 5.6 4.6 1.1 8.2 1.4 3.7 3.7 0.9 2.2 7.5 6.9 0.9 21.6 9.2 4.4 12.9 4.4 4.8 8.1 3.4 1.3 2.4 4.8 38.4 5.8 16.6 1.0 1.3 3.7 175.6 0.2 12.3 3.3 1.6 4.8 6.3 1.9 62.0 20.9 1.4 1.7 7.6 2.9 1.0 18.7 10.0 1.9 0.9 2.2 4.7 4.9 14.5 8.2 4.3 11.1 8.3 1.1 0.3 5.1 37.6 7.3 2.1 2.8 0.5 0.7 12.6 19.1 1.0 16.6 23.9 18.4 21.8 10.7 12.0 32.4 0.5 27.2 8.9 5.8 7.3 9.6 6.8 1.2 1.2 3.0 0.1 46.2 0.6 0.9 21.3 14.2 14.1 26.3 10.4 0.4 42.0 6.7 6.0 4.8 1.1 1.4 5.3 13.3 0.8 42.0 2.3 0.4 6.9 2.0 5.5 8.3 3.7 0.5 1.0 8.3 3.6 0.7 0.3 0.3 24.6 20.3 16.4 2.2 0.7 5.9 0.9 0.2 0.6 22.5 0.3 37.6 11.1 15.6 17.7 0.3 4.8 9.4 14.4 1.1 5.1 0.1 8.3 6.4 7.3 1.1 1.4 0.9 2.2 1.3 2.4 1.0 1.3 1.6 0.9 FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FK506 binding protein 14" Q9NWM8 7 30010587-30026684 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: AB_1848613, HPA026829: AB_10601651" "prognostic unfavourable (1.60e-4)" "unprognostic (1.12e-3)" "unprognostic (6.84e-2)" "unprognostic (1.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-3)" "prognostic unfavourable (6.87e-4)" "unprognostic (6.06e-2)" "unprognostic (7.00e-2)" "unprognostic (6.99e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-3)" "prognostic unfavourable (4.57e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "prognostic unfavourable (4.25e-4)" 8.8 7.4 8.7 9.2 7.3 5.1 8.8 17.6 7.7 14.9 7.8 4.1 6.9 4.2 12.1 14.2 8.0 8.1 8.5 9.8 7.1 5.2 5.4 9.2 7.6 8.1 9.2 5.2 13.0 9.8 8.6 27.8 10.7 7.1 9.8 6.9 8.4 7.6 10.9 3.3 6.4 5.3 18.8 8.1 6.7 7.2 4.2 7.1 2.6 5.6 5.9 7.7 13.4 8.7 1.6 3.3 2.7 1.2 1.0 1.6 0.6 3.4 2.6 7.3 17.0 19.1 24.5 3.4 17.5 16.4 6.1 12.0 2.2 2.2 1.2 8.3 15.3 7.5 4.1 6.4 12.3 0.6 5.8 2.7 4.9 6.4 9.7 1.9 4.8 15.3 6.7 10.6 12.6 13.5 4.4 2.5 11.0 1.4 1.0 2.4 3.8 4.7 0.0 4.9 4.0 6.1 3.0 1.9 6.4 6.2 14.0 4.3 3.2 2.6 10.9 6.6 7.7 11.2 6.9 3.9 4.0 2.1 9.3 1.9 20.3 1.9 1.2 1.2 1.3 0.8 1.0 1.1 1.6 1.1 2.2 1.6 1.5 1.3 2.7 1.0 0.5 3.3 1.4 0.6 8.7 7.3 17.6 7.7 7.1 5.2 9.2 5.2 7.1 7.1 FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FK506 binding protein 1A" P62942 20 1368978-1393172 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 149.0;TIME: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 63.6;granulocytes: 88.4;monocytes: 94.3" "CAB004639, HPA051798" Uncertain 16000000 "CAB004639: AB_425434, HPA051798: " "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavourable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavourable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" 106.0 42.4 67.3 55.0 114.8 44.4 63.5 15.8 55.8 33.2 39.7 22.1 33.8 32.7 45.5 45.9 42.7 33.8 32.0 36.4 51.7 30.6 41.9 41.7 59.2 84.1 26.0 36.5 41.7 57.7 20.6 21.7 65.0 22.5 34.4 49.4 21.4 30.8 40.6 38.9 31.5 37.1 56.0 23.3 68.0 33.0 21.1 28.4 47.4 62.2 39.7 48.3 48.1 37.0 13.3 63.6 88.4 94.3 14.5 18.6 84.3 69.9 19.4 15.5 22.4 52.4 65.7 20.4 44.5 30.2 35.7 33.1 19.3 27.2 28.6 14.3 41.4 32.2 19.9 81.3 46.9 8.2 21.7 29.4 9.1 36.8 32.2 34.1 16.3 38.2 26.0 32.9 34.0 149.0 26.9 14.7 41.9 8.7 33.3 47.0 33.2 38.0 28.6 27.0 34.7 46.0 17.7 25.8 19.5 22.0 44.3 73.6 17.4 29.1 172.6 132.5 22.2 28.2 32.8 7.4 15.9 30.0 22.8 34.6 29.3 23.9 79.4 88.4 11.5 94.3 10.2 12.8 13.9 13.2 63.6 13.3 14.8 14.2 77.9 14.5 90.3 31.6 18.6 84.3 67.3 114.8 15.8 55.8 51.7 30.6 26.0 36.5 22.5 28.4 FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FK506 binding protein 1B" P68106 2 24049701-24063681 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.1;intestine: 24.9" "Cell line enhanced" "Detected in many" "Hep G2: 22.8;NTERA-2: 22.2;SH-SY5Y: 16.1;TIME: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 5.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045572, HPA051798" Uncertain Approved Vesicles Vesicles "HPA045572: , HPA051798: " "unprognostic (3.01e-3)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "unprognostic (9.89e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" 2.9 5.9 25.0 2.8 30.7 1.9 5.9 15.7 23.1 5.1 7.2 1.6 7.4 24.9 3.6 4.2 4.5 4.5 7.1 3.4 31.1 14.0 4.4 4.6 9.0 2.2 13.0 19.7 4.6 4.9 6.4 2.8 5.6 7.9 5.1 4.6 2.4 3.3 9.2 1.1 3.6 6.7 4.0 5.2 1.8 13.3 1.6 4.4 0.6 5.0 1.1 3.2 7.1 3.5 1.5 2.2 4.4 0.8 0.3 5.4 1.1 0.1 1.0 8.9 0.0 5.6 2.2 3.1 3.0 3.1 1.3 1.9 0.6 1.0 0.0 2.2 5.2 3.4 13.1 10.2 0.8 1.5 8.4 3.0 0.1 22.8 2.1 0.0 7.3 2.1 2.4 3.0 0.6 8.3 0.7 0.0 2.9 0.1 0.9 0.0 22.2 1.5 1.5 0.7 0.0 1.0 0.6 2.2 16.1 0.1 0.0 2.8 0.6 1.1 19.4 0.0 2.8 0.1 0.7 0.5 0.2 0.0 3.2 0.0 0.7 1.3 0.8 4.4 0.3 0.7 0.0 0.3 0.6 0.5 2.2 1.5 0.0 0.2 0.1 0.3 0.0 0.4 5.4 1.1 25.0 30.7 15.7 23.1 31.1 14.0 13.0 19.7 7.9 4.4 FKBP2 "FKBP-13, PPIase" ENSG00000173486 "FK506 binding protein 2" P26885 11 64241003-64244132 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 119.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" 400000 "Plasma membrane" "CAB025561: , HPA049405: " "unprognostic (4.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.77e-2)" "unprognostic (2.66e-3)" "unprognostic (7.40e-2)" "unprognostic (1.92e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-1)" "unprognostic (3.23e-1)" "unprognostic (5.91e-3)" "unprognostic (5.86e-2)" "unprognostic (7.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (5.23e-1)" "unprognostic (2.30e-1)" "unprognostic (3.57e-2)" 18.2 35.8 28.9 20.2 35.5 12.1 20.2 18.8 27.1 31.3 28.0 20.3 87.8 39.0 24.4 102.7 20.8 25.5 30.3 28.0 29.7 35.7 40.3 89.6 18.8 17.0 39.3 24.8 22.1 107.2 34.0 57.2 59.2 29.0 26.1 21.9 19.4 59.3 116.6 11.8 18.5 30.2 19.7 28.5 20.9 31.1 19.8 20.6 12.4 63.2 18.6 18.8 21.3 23.9 21.3 119.6 29.0 25.4 20.0 30.7 15.5 24.0 31.7 17.2 34.7 37.2 21.3 24.4 29.2 29.6 22.1 20.6 31.2 54.2 17.8 46.5 35.8 31.5 13.6 24.2 10.5 22.1 11.8 19.8 42.2 31.9 48.9 16.4 27.8 24.7 36.1 29.2 32.4 17.5 14.8 53.4 26.2 39.8 17.9 25.9 20.0 28.6 16.0 17.0 64.9 39.9 24.1 24.0 20.9 20.0 56.7 32.1 21.8 14.2 16.6 26.6 23.7 42.2 15.6 32.5 10.1 14.5 35.6 17.3 30.0 29.0 24.5 3.4 24.1 25.4 30.7 21.3 19.2 23.3 23.2 20.5 13.0 18.1 9.1 20.0 20.8 119.6 7.1 15.5 28.9 35.5 18.8 27.1 29.7 35.7 39.3 24.8 29.0 20.6 FKBP3 "FKBP-25, PPIase" ENSG00000100442 "FK506 binding protein 3" Q00688 14 45115600-45135319 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 113.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000864, CAB012232, CAB012520" Supported Supported Cytosol 980000 Cytosol "CAB012232: , CAB012520: AB_873554, HPA000864: AB_1078873" "unprognostic (7.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (9.72e-2)" "unprognostic (1.25e-1)" "unprognostic (9.82e-3)" "unprognostic (3.58e-3)" "unprognostic (2.28e-1)" "unprognostic (5.04e-3)" "unprognostic (1.22e-3)" "unprognostic (7.47e-2)" "unprognostic (6.92e-3)" "unprognostic (1.00e-1)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-2)" "unprognostic (1.47e-1)" 11.7 13.2 28.1 10.2 40.7 9.8 15.5 25.1 32.1 12.0 14.6 11.4 8.3 13.2 9.9 20.4 14.6 8.8 9.1 31.3 26.0 24.4 16.5 20.5 8.0 14.6 23.2 23.8 9.9 10.9 15.0 17.1 14.0 22.9 17.9 15.2 6.6 10.7 12.2 113.3 11.3 13.9 12.8 19.6 9.9 10.6 13.5 22.4 12.7 12.4 24.2 16.5 12.7 9.3 19.5 27.5 13.5 17.4 15.4 19.4 13.0 36.9 41.2 60.0 31.5 26.7 29.2 23.7 22.7 26.1 36.0 39.7 36.0 31.8 19.7 24.0 25.6 30.8 44.5 29.3 51.3 28.5 26.6 16.2 32.0 46.5 26.4 28.0 17.6 27.5 30.6 20.9 19.5 46.8 23.4 14.9 42.6 45.2 44.8 37.5 30.4 39.1 43.2 44.2 23.9 57.5 42.8 36.6 14.3 36.4 22.7 34.8 53.1 21.0 30.1 27.5 47.6 14.4 17.4 25.1 44.6 30.7 16.6 19.3 25.6 11.6 14.6 13.5 13.0 17.2 15.7 19.5 17.5 17.6 21.8 13.6 16.8 18.8 2.3 15.4 17.4 27.5 19.4 13.0 28.1 40.7 25.1 32.1 26.0 24.4 23.2 23.8 22.9 22.4 FKBP4 "FKBP52, FKBP59" ENSG00000004478 "FK506 binding protein 4" Q02790 12 2794953-2805423 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "vagina: 209.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006148, CAB017441, HPA062857" Approved Enhanced Nucleoplasm,Cytosol 110000 Cytosol Nucleoplasm "CAB017441: AB_10618759, HPA006148: AB_1078875, HPA062857: " "unprognostic (1.46e-2)" "unprognostic (1.73e-2)" "unprognostic (1.31e-2)" "prognostic unfavourable (7.65e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-1)" "prognostic unfavourable (6.12e-5)" "prognostic unfavourable (1.44e-4)" "unprognostic (3.43e-1)" "unprognostic (3.25e-2)" "unprognostic (1.72e-1)" "unprognostic (3.14e-1)" "unprognostic (3.89e-2)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (2.22e-1)" 16.2 21.6 26.0 13.7 30.7 13.3 40.7 50.4 31.9 19.9 22.6 22.8 36.2 13.1 20.1 30.7 34.2 25.7 16.4 20.4 25.0 32.5 31.6 31.3 15.8 11.7 44.7 23.4 23.9 30.3 30.1 19.5 32.0 39.4 30.2 25.3 11.5 30.1 31.6 33.5 25.3 16.1 26.4 25.2 11.5 25.3 36.0 42.1 15.6 47.1 16.5 18.5 17.4 209.6 13.8 6.0 10.9 13.7 8.4 14.0 9.9 15.5 34.6 10.0 16.8 12.5 7.4 48.1 15.3 5.5 25.3 17.2 34.4 19.0 20.8 4.4 9.8 21.3 62.3 20.7 30.5 38.0 39.9 22.9 25.5 12.2 9.6 17.9 6.2 6.7 19.0 29.9 30.0 14.7 21.0 29.7 10.1 44.7 31.3 16.2 85.5 25.0 18.8 17.6 12.4 21.3 19.9 14.5 20.8 17.7 48.4 7.7 65.3 12.1 7.8 12.5 39.3 14.0 38.5 7.4 11.3 30.7 11.1 26.7 12.7 10.9 10.8 5.9 12.5 9.8 14.0 13.3 11.1 11.8 6.0 13.8 11.8 13.7 1.5 8.4 13.7 5.3 10.1 9.9 26.0 30.7 50.4 31.9 25.0 32.5 44.7 23.4 39.4 42.1 FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FK506 binding protein 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 277.2" "Cell line enhanced" "Detected in many" "ASC diff: 101.4;ASC TERT1: 63.1;HHSteC: 79.4;HSkMC: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB009315: AB_2278350, HPA031092: AB_10600195, HPA031093: AB_10601748, HPA031095: " "unprognostic (2.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.72e-1)" "unprognostic (6.30e-3)" "unprognostic (3.70e-3)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (7.48e-3)" "unprognostic (2.18e-3)" "unprognostic (8.31e-2)" "unprognostic (4.22e-2)" "unprognostic (6.90e-3)" 78.8 20.7 9.5 14.2 15.6 4.9 36.7 2.4 10.9 16.5 29.0 5.1 29.8 2.2 18.6 16.9 29.2 19.4 17.9 26.3 10.6 4.2 44.9 30.7 19.7 55.9 15.7 3.6 27.2 43.7 8.6 33.8 6.0 13.1 18.3 8.2 11.8 30.4 25.1 277.2 20.2 36.7 18.6 18.2 32.3 25.0 14.3 12.4 20.1 24.2 9.8 16.8 22.5 18.4 4.0 30.6 24.9 31.2 11.8 42.3 39.9 4.9 2.1 9.5 14.2 101.4 63.1 0.1 2.7 0.1 1.7 4.1 3.7 0.8 24.5 2.5 0.5 0.0 5.6 11.9 4.2 9.6 5.3 10.5 1.8 5.2 79.4 6.6 1.0 95.9 48.2 3.1 29.1 10.3 11.2 10.0 18.6 3.1 27.3 12.4 2.4 1.6 12.2 2.4 11.9 7.9 3.0 3.6 2.2 2.2 2.5 0.5 14.0 7.8 22.7 2.5 2.2 0.3 3.7 4.5 5.2 31.1 0.8 12.9 0.9 13.7 31.2 19.4 20.0 27.0 23.8 3.0 28.2 20.8 30.6 4.0 42.3 30.2 24.9 11.8 12.0 9.2 10.3 39.9 9.5 15.6 2.4 10.9 10.6 4.2 15.7 3.6 13.1 12.4 FKBP7 FKBP23 ENSG00000079150 "FK506 binding protein 7" Q9Y680 2 178463664-178478600 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 51.9;ASC TERT1: 32.2;HSkMC: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavourable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.6 4.6 1.5 4.3 4.1 0.7 11.1 3.5 2.3 20.5 6.9 1.0 10.0 1.8 21.4 21.9 8.4 12.4 12.8 12.1 1.5 1.5 5.5 7.4 6.8 5.2 4.0 1.8 34.6 4.3 1.5 11.1 8.2 2.9 19.5 4.2 7.1 4.9 9.7 4.4 4.0 3.9 19.9 3.9 3.0 5.3 8.3 2.2 2.2 8.7 8.0 2.3 15.5 9.9 2.8 5.8 0.2 1.6 1.2 2.8 0.8 0.0 0.6 6.0 8.9 51.9 32.2 0.5 10.7 17.8 1.9 6.3 0.1 0.6 1.7 2.4 19.5 0.1 2.2 0.9 3.4 1.3 1.2 1.7 2.4 1.7 8.0 1.0 1.2 21.6 0.4 7.9 1.1 6.3 0.7 1.1 8.2 0.1 1.9 1.9 1.2 0.9 2.5 10.5 2.3 2.7 0.2 3.2 10.4 2.3 0.0 1.8 0.1 2.0 5.9 3.7 2.2 4.2 1.0 2.1 2.1 0.8 6.6 2.7 7.9 0.0 1.1 0.1 2.3 1.6 2.8 2.8 2.0 1.6 5.8 1.7 2.2 2.4 0.2 1.2 0.0 4.5 2.2 0.8 1.5 4.1 3.5 2.3 1.5 1.5 4.0 1.8 2.9 2.2 FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FK506 binding protein 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 32.5;neutrophil: 31.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: " "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (1.24e-4)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (9.22e-2)" "unprognostic (2.54e-2)" "unprognostic (2.26e-1)" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "prognostic favourable (7.76e-4)" "unprognostic (8.51e-2)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (6.89e-2)" "unprognostic (1.12e-2)" "unprognostic (2.32e-1)" 44.3 38.1 75.9 27.5 82.1 82.5 26.5 43.4 113.7 35.2 31.9 41.2 34.6 31.1 31.4 27.2 48.7 39.3 34.5 43.4 69.6 62.1 28.9 42.7 34.3 31.1 55.3 54.3 56.1 60.4 28.8 42.2 36.6 51.2 36.5 12.9 31.9 73.1 46.1 56.7 35.1 31.6 34.6 46.3 36.7 31.9 49.5 26.9 32.1 38.8 24.2 30.7 36.3 45.8 4.3 4.3 32.5 6.9 3.1 6.6 9.1 36.6 26.3 20.6 39.1 21.3 33.5 51.7 29.7 31.6 22.7 31.5 24.9 50.0 21.0 48.3 36.4 19.9 12.7 41.3 6.4 25.6 60.3 19.6 34.3 29.9 36.7 19.4 43.2 43.7 39.9 20.4 13.0 23.3 41.1 50.0 19.7 61.0 35.2 58.1 42.1 38.2 37.0 17.1 71.8 30.5 24.0 22.9 41.7 20.8 17.2 37.0 20.2 56.7 27.1 28.4 26.0 55.4 22.5 38.3 21.9 24.4 64.3 31.2 25.2 6.3 5.6 32.5 6.0 5.8 5.5 4.1 6.1 6.6 4.3 4.3 4.7 5.3 31.0 3.1 6.9 4.3 6.0 9.1 75.9 82.1 43.4 113.7 69.6 62.1 55.3 54.3 51.2 26.9 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FK506 binding protein 9" O95302 7 32957404-33006931 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 57.5;fHDF/TERT166: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: " "unprognostic (1.23e-2)" "prognostic unfavourable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavourable (5.80e-4)" "prognostic unfavourable (2.02e-4)" "prognostic unfavourable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavourable (7.02e-6)" 35.4 21.1 9.7 12.5 13.6 0.9 43.7 4.5 16.3 33.6 18.3 9.3 16.8 8.8 31.3 30.9 23.7 24.1 28.8 44.4 9.7 11.9 18.2 10.1 30.6 17.5 10.8 9.7 25.9 26.0 12.9 16.0 35.2 13.2 23.7 21.2 30.4 16.0 25.6 17.1 28.0 13.4 37.0 12.8 10.7 17.4 16.3 6.4 2.9 18.9 19.4 11.1 23.7 23.6 0.4 1.4 7.4 4.1 0.3 0.1 0.9 7.0 13.4 5.2 21.6 49.7 57.5 7.0 38.1 39.7 12.6 20.1 5.8 16.8 0.0 15.6 70.8 13.8 7.7 18.6 14.5 0.0 2.3 1.2 14.4 5.8 20.7 0.0 2.0 37.3 11.3 11.2 10.9 15.8 2.7 1.4 25.6 6.8 0.0 3.5 1.1 7.1 0.0 14.1 0.0 14.1 2.4 4.9 12.0 21.7 11.1 13.5 7.8 3.4 21.2 20.7 19.9 12.8 8.7 4.6 8.8 0.0 20.2 0.0 41.1 1.5 4.1 0.9 0.1 2.6 0.1 0.4 0.1 0.0 1.4 0.3 0.1 0.1 7.4 0.3 0.7 0.3 0.0 0.9 9.7 13.6 4.5 16.3 9.7 11.9 10.8 9.7 13.2 6.4 FLAD1 "FAD1, PP591" ENSG00000160688 "Flavin adenine dinucleotide synthetase 1" Q8NFF5 1 154983338-154993111 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028476, HPA028486, HPA028563" Approved Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA028476: AB_10599974, HPA028486: AB_10600206, HPA028563: AB_10602286" "unprognostic (2.64e-1)" "unprognostic (2.60e-1)" "unprognostic (2.72e-1)" "unprognostic (3.84e-2)" "unprognostic (7.34e-2)" "unprognostic (1.45e-1)" "prognostic unfavourable (3.04e-4)" "unprognostic (1.31e-1)" "unprognostic (2.32e-1)" "unprognostic (8.08e-2)" "unprognostic (6.51e-2)" "unprognostic (9.74e-2)" "prognostic unfavourable (2.55e-6)" "unprognostic (1.67e-2)" "unprognostic (5.06e-2)" "unprognostic (5.50e-2)" "unprognostic (1.17e-2)" 16.5 16.5 20.3 15.5 18.9 12.1 17.4 15.9 20.8 14.1 16.4 19.3 14.7 19.6 15.9 21.2 19.8 16.7 11.8 16.1 18.2 10.4 19.0 36.5 13.5 20.0 20.8 15.6 14.5 19.0 13.6 12.0 18.5 15.9 18.7 19.0 16.1 16.2 16.3 26.3 23.3 23.9 17.6 12.4 22.9 16.1 19.1 18.9 15.7 20.8 18.4 22.0 15.5 15.4 25.1 24.5 15.2 24.1 14.9 26.4 22.7 13.1 21.2 13.5 23.0 11.8 8.7 25.7 10.0 8.3 14.6 12.5 18.8 16.3 15.4 20.2 9.2 17.3 25.8 20.7 9.5 16.0 19.4 12.5 16.8 13.2 16.1 18.0 16.3 12.4 27.2 16.6 17.8 16.9 20.0 12.5 12.3 28.4 12.4 12.6 29.4 22.0 20.9 6.7 35.3 13.9 18.4 22.8 31.3 15.6 35.4 19.7 30.3 27.4 10.7 9.2 12.7 11.8 15.7 19.6 24.3 26.5 11.1 14.7 14.7 15.2 23.0 14.8 24.0 20.9 26.4 25.1 22.1 22.7 24.1 20.5 20.5 20.2 5.2 14.9 24.1 24.5 23.3 22.7 20.3 18.9 15.9 20.8 18.2 10.4 20.8 15.6 15.9 18.9 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related tyrosine kinase 1" P17948 13 28300344-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "placenta: 155.3" "Cell line enhanced" "Detected in some" "BJ: 17.0;BJ hTERT+: 13.5;HMC-1: 84.6;HUVEC TERT2: 15.3;WM-115: 30.3" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 1.1;naive B-cell: 3.7;neutrophil: 2.1" "Group enriched" "Detected in many" 5 "B-cells: 3.7;granulocytes: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" 875697 54000 "Plasma membrane, Actin filaments" "CAB068189: , CAB068190: , HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavourable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 18.9 4.0 9.9 4.0 14.3 1.2 13.5 8.0 15.9 7.1 4.6 3.5 1.7 3.5 7.2 2.2 3.4 4.0 6.9 18.3 11.4 7.3 10.3 7.6 12.3 2.5 10.3 3.2 5.1 5.4 13.4 3.7 155.3 13.8 5.1 3.1 9.1 3.0 5.0 12.5 2.6 3.4 7.3 9.6 7.2 4.6 6.8 10.2 0.0 19.1 3.8 2.8 7.6 9.2 3.7 0.5 2.1 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 17.0 13.5 6.2 3.6 0.0 0.0 0.0 0.0 2.2 0.0 1.6 0.0 11.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 84.6 0.1 0.0 0.0 0.2 15.3 0.4 0.0 0.0 0.0 1.0 0.8 9.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.5 0.2 0.0 0.1 0.0 30.3 0.2 0.1 0.1 0.1 0.1 0.0 1.1 0.1 0.1 0.0 3.7 0.4 0.4 2.1 0.2 0.1 0.5 0.2 0.2 9.9 14.3 8.0 15.9 11.4 7.3 10.3 3.2 13.8 10.2 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 29.9;brain: 19.3;lymphoid tissue: 15.0" "Group enriched" "Detected in some" 11 "REH: 27.8;THP-1: 17.1" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in many" "cerebellum: 19.3" "Group enriched" "Detected in some" 11 "myeloid DC: 29.9;plasmacytoid DC: 12.1" "Lineage enriched" "Detected in many" 16 "dendritic cells: 29.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" 180000 "Endoplasmic reticulum" "HPA047539: " "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.9 0.6 0.6 7.2 1.1 7.5 2.6 19.3 3.5 0.9 1.2 0.1 0.1 0.4 0.8 0.8 1.0 1.2 4.6 0.5 0.9 1.7 2.8 0.7 2.7 15.0 1.8 1.1 0.5 5.7 0.0 0.4 0.0 7.4 0.6 1.4 0.1 2.3 0.6 0.4 1.2 3.0 1.3 4.4 8.8 0.9 1.2 0.0 8.2 0.6 0.0 5.8 2.4 0.7 0.1 29.9 1.4 1.8 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.5 0.0 27.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.8 1.4 0.0 0.3 0.0 0.1 0.0 0.0 29.9 0.0 0.0 0.0 0.0 0.8 0.0 12.1 0.0 1.2 0.6 1.1 19.3 3.5 0.9 1.7 1.8 1.1 7.4 0.0 FLT4 "PCL, VEGFR3" ENSG00000037280 "Fms related tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 56.3" "Cell line enhanced" "Detected in some" "AN3-CA: 8.3;BEWO: 10.2;HEK 293: 12.6;HL-60: 7.4;HUVEC TERT2: 8.1;T-47d: 12.0;TIME: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "MAIT T-cell: 7.7" "Lineage enriched" "Detected in single" 35 "T-cells: 7.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906" Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Secreted to blood" 270000000 "Plasma membrane" "Nucleoplasm, Cell Junctions" "CAB000099: , HPA046519: , HPA067906: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 14.8 7.1 1.6 4.9 6.0 0.7 28.5 1.3 2.7 6.3 7.3 1.9 2.1 3.1 7.3 6.2 5.7 9.2 5.3 6.4 1.7 0.9 11.7 10.2 14.1 23.6 2.0 0.8 5.8 2.3 2.3 6.2 56.3 2.1 4.9 1.4 6.7 3.3 4.4 4.8 2.8 4.7 4.7 1.5 14.5 2.4 3.5 2.0 0.3 19.4 4.4 2.3 6.1 14.7 0.0 0.1 0.2 0.0 0.0 7.7 0.2 0.1 2.0 2.7 8.3 0.0 0.0 10.2 0.2 0.1 0.0 0.0 0.3 0.3 0.2 0.8 0.1 0.3 2.8 0.1 0.2 0.1 12.6 1.0 0.4 0.4 0.1 7.4 0.2 0.2 0.0 0.1 0.3 8.1 0.3 0.3 1.7 4.5 0.1 0.4 5.8 0.5 6.5 0.0 0.1 0.1 0.2 0.2 0.9 0.1 0.2 0.0 12.0 0.2 12.7 0.1 5.9 0.2 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.9 0.0 7.7 0.0 0.4 1.6 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 1.6 6.0 1.3 2.7 1.7 0.9 2.0 0.8 2.1 2.0 FMO1 ENSG00000010932 "Flavin containing monooxygenase 1" Q01740 1 171248471-171285978 "Enzymes, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 70.4" "Cell line enriched" "Detected in some" 7 "HSkMC: 21.5" "Cancer enriched" "Detected in many" 8 "renal cancer: 18.0" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 36 "naive B-cell: 3.5" "Lineage enriched" "Detected in single" 36 "B-cells: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA023680 Uncertain "HPA023680: AB_1848966" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (5.87e-2)" "unprognostic (1.34e-1)" "unprognostic (5.32e-3)" "unprognostic (1.89e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "unprognostic (9.16e-2)" "unprognostic (9.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.23e-1)" "prognostic favourable (2.81e-4)" "unprognostic (6.49e-4)" "unprognostic (1.40e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" 3.4 3.6 0.1 0.1 0.3 0.0 5.6 0.1 0.4 5.6 0.8 0.3 0.8 0.0 2.5 3.0 5.0 3.3 1.8 0.9 0.1 0.0 70.4 1.0 0.8 0.1 0.1 0.1 5.9 2.4 0.1 1.1 0.8 0.2 1.1 0.0 4.0 4.2 1.5 0.1 4.0 14.4 1.5 0.1 0.1 0.5 1.6 0.1 1.8 1.7 5.3 10.3 1.4 1.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 21.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.4 0.1 0.0 0.1 0.1 0.2 0.1 FMO2 ENSG00000094963 "Flavin containing monooxygenase 2" Q99518 1 171185208-171211230 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.0;esophagus: 35.3;lung: 53.0" "Group enriched" "Detected in some" 57 "ASC diff: 24.0;ASC TERT1: 10.9;HSkMC: 28.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA028261 Approved "HPA028261: AB_10601012" "unprognostic (1.85e-2)" "unprognostic (3.14e-2)" "unprognostic (7.44e-2)" "unprognostic (3.75e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" "unprognostic (3.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.58e-2)" "unprognostic (1.16e-1)" "unprognostic (4.28e-1)" "unprognostic (1.53e-1)" "unprognostic (1.26e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (3.83e-2)" 40.0 11.8 1.2 1.7 4.4 0.0 22.5 1.5 0.6 7.6 5.0 0.6 2.9 0.3 1.9 3.5 35.3 6.7 2.0 17.4 1.8 1.2 9.4 1.8 53.0 5.7 3.9 1.2 6.1 2.1 1.8 7.0 0.0 2.4 6.0 0.7 8.3 14.0 1.3 7.6 1.7 1.5 2.5 1.9 0.4 2.4 3.3 1.3 0.4 5.8 6.8 5.5 5.0 10.2 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 28.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.2 4.4 1.5 0.6 1.8 1.2 3.9 1.2 2.4 1.3 FMO3 ENSG00000007933 "Flavin containing monooxygenase 3" P31513 1 171090877-171117819 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 170.2" "Group enriched" "Detected in some" 4 "ASC diff: 24.8;ASC TERT1: 18.8" "Cancer enriched" "Detected in many" 13 "liver cancer: 94.9" "Region enriched" "Detected in single" 5 "pons and medulla: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA013750 Enhanced "HPA013750: AB_1848968" "unprognostic (1.87e-2)" "unprognostic (6.30e-2)" "unprognostic (1.00e-1)" "unprognostic (6.81e-3)" "unprognostic (2.64e-1)" "unprognostic (1.31e-3)" "prognostic favourable (3.46e-4)" "prognostic favourable (5.60e-5)" "unprognostic (2.95e-1)" "unprognostic (9.34e-2)" "unprognostic (3.02e-1)" "unprognostic (7.21e-2)" "prognostic unfavourable (1.13e-4)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (7.27e-2)" 9.5 2.0 0.0 0.8 0.2 0.0 1.3 0.1 0.1 0.2 0.8 0.1 0.1 0.3 0.6 1.2 1.7 2.3 0.3 0.8 0.0 0.1 6.4 170.2 3.7 1.5 0.2 0.0 0.9 0.7 0.3 2.7 0.0 1.4 0.2 0.1 3.6 0.9 0.1 1.9 0.8 0.4 0.2 0.1 0.1 0.6 0.5 0.1 0.0 0.8 1.2 2.6 0.2 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 18.8 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.0 1.4 0.1 FMO4 FMO2 ENSG00000076258 "Flavin containing monooxygenase 4" P31512 1 171314208-171342084 "Enzymes, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 33.8;liver: 42.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.2;EFO-21: 7.9;HSkMC: 9.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA049100, HPA072438" Uncertain Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA049100: , HPA072438: " "unprognostic (1.83e-2)" "unprognostic (1.17e-1)" "unprognostic (6.18e-2)" "unprognostic (3.01e-2)" "unprognostic (8.27e-2)" "unprognostic (4.13e-1)" "prognostic favourable (1.09e-4)" "prognostic favourable (7.45e-4)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (5.99e-2)" "unprognostic (2.90e-1)" "prognostic favourable (6.96e-4)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (7.45e-3)" "unprognostic (1.95e-1)" 5.3 3.6 1.4 5.1 4.8 0.9 4.5 0.6 2.7 4.5 6.0 4.8 3.1 4.2 3.0 10.0 4.6 3.8 4.6 6.3 2.3 1.5 33.8 42.2 3.4 2.8 7.5 2.8 4.1 3.2 5.5 5.0 2.3 3.7 3.9 3.7 6.7 2.7 2.0 1.6 2.9 16.1 2.0 7.0 3.8 3.9 2.0 6.2 2.7 4.5 3.3 3.4 2.9 3.7 5.3 2.9 0.9 4.0 3.9 4.9 2.0 0.1 0.0 0.4 0.6 5.4 4.9 0.2 1.1 5.0 1.6 1.7 0.8 7.2 4.4 7.9 0.0 0.3 0.8 1.3 2.2 2.1 1.1 0.0 0.0 0.1 0.8 0.9 1.0 9.3 3.1 0.6 1.3 0.3 0.2 3.3 0.7 1.0 2.1 1.9 0.5 1.6 0.4 0.4 2.5 3.5 0.0 0.2 0.0 1.4 1.5 3.0 3.1 1.3 0.1 1.3 0.4 1.4 1.0 4.0 1.3 2.7 2.4 1.4 1.1 0.6 2.6 0.9 2.5 4.0 1.8 3.1 2.4 3.3 2.2 5.3 3.3 2.5 0.5 3.9 2.7 2.9 4.9 2.0 1.4 4.8 0.6 2.7 2.3 1.5 7.5 2.8 3.7 6.2 FMO5 ENSG00000131781 "Flavin containing monooxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 61.1;liver: 119.4;stomach 1: 38.6" "Cell line enhanced" "Detected in some" "Hep G2: 28.4;HMC-1: 6.4;THP-1: 7.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Group enriched" "Detected in many" 6 "basal ganglia: 5.5;cerebral cortex: 4.5;midbrain: 17.1;pons and medulla: 5.2;thalamus: 6.0" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favourable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" 1.1 2.4 1.1 1.9 5.5 0.2 8.6 0.6 4.5 1.3 61.1 1.5 0.8 12.5 1.0 1.3 0.7 1.1 8.5 1.0 1.3 0.5 9.0 119.4 17.0 0.8 17.1 0.5 1.0 11.9 8.8 4.9 0.6 5.2 1.9 8.2 0.5 9.7 0.6 0.4 4.2 53.6 0.9 7.1 1.2 38.6 1.2 6.0 0.2 1.1 1.5 0.5 1.9 0.8 9.2 4.9 6.2 12.1 1.0 2.0 3.6 0.1 0.7 0.5 0.0 1.9 0.5 0.6 0.4 0.3 0.2 0.6 0.4 1.5 0.3 0.5 0.4 0.3 0.0 0.0 0.0 1.0 0.1 1.1 0.0 28.4 0.6 0.9 6.4 0.9 0.1 0.3 0.0 0.4 0.1 0.1 1.1 0.9 0.2 0.5 2.0 0.5 0.3 0.3 0.2 2.4 0.4 0.4 0.2 0.6 1.9 0.9 1.4 7.2 0.7 0.0 0.2 0.6 0.0 0.2 0.0 0.2 0.7 0.3 0.2 6.2 12.1 3.5 2.0 5.6 0.3 3.6 0.5 0.6 4.9 9.2 0.3 1.3 1.2 1.0 1.6 2.4 1.4 3.6 1.1 5.5 0.6 4.5 1.3 0.5 17.1 0.5 5.2 6.0 FNTA "FPTA, PGGT1A, PTAR2" ENSG00000168522 "Farnesyltransferase, CAAX box, alpha" P49354 8 43034194-43085788 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010149, HPA018830" Approved Approved Cytosol 220000 Cytosol "CAB010149: AB_2106299, HPA018830: AB_1848992" "unprognostic (2.09e-1)" "unprognostic (1.35e-1)" "unprognostic (2.90e-1)" "unprognostic (1.86e-3)" "unprognostic (2.64e-1)" "unprognostic (4.70e-3)" "unprognostic (1.83e-2)" "unprognostic (3.69e-2)" "unprognostic (1.70e-2)" "unprognostic (5.37e-2)" "unprognostic (3.25e-2)" "unprognostic (4.10e-1)" "prognostic unfavourable (2.94e-12)" "unprognostic (3.63e-2)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (1.29e-3)" 32.5 21.5 25.3 20.9 31.9 15.3 29.8 21.2 28.8 26.7 25.7 36.9 25.0 23.7 23.7 29.4 28.0 22.9 18.1 32.6 25.6 23.1 24.0 30.5 22.7 27.4 43.3 23.8 21.5 26.0 17.9 24.7 32.6 33.4 25.1 22.5 14.1 23.6 25.9 45.2 29.7 20.4 23.9 75.9 22.9 20.9 18.3 36.8 26.0 25.4 26.8 28.1 27.1 29.8 11.7 11.7 11.1 8.9 13.9 11.9 5.3 23.5 11.7 16.1 5.2 28.4 37.0 13.4 13.7 16.1 16.1 14.8 18.9 18.2 27.7 10.6 17.2 12.9 19.8 22.8 18.9 7.2 13.1 21.7 8.0 16.3 37.0 8.8 11.6 28.6 37.3 11.5 33.1 27.6 26.2 16.3 17.6 2.8 21.1 13.5 28.0 8.5 18.5 25.6 14.9 22.0 17.5 9.6 14.9 17.8 14.8 23.5 18.8 16.8 22.1 5.4 7.1 21.8 14.5 15.2 12.9 27.1 14.2 17.2 12.6 3.0 6.6 11.1 8.7 8.9 10.3 11.7 9.1 11.7 11.7 11.6 11.9 11.9 1.6 13.9 6.7 11.0 11.5 5.3 25.3 31.9 21.2 28.8 25.6 23.1 43.3 23.8 33.4 36.8 FNTB FPTB ENSG00000257365 "Farnesyltransferase, CAAX box, beta" P49356 14 64986720-65062652 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 75.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062743 Uncertain Approved Centrosome Centrosome "HPA062743: " "unprognostic (2.79e-1)" "unprognostic (1.50e-2)" "unprognostic (1.54e-1)" "unprognostic (8.57e-3)" "unprognostic (1.88e-1)" "unprognostic (6.88e-2)" "prognostic unfavourable (6.03e-4)" "unprognostic (6.21e-2)" "unprognostic (3.11e-2)" "unprognostic (1.46e-2)" "unprognostic (1.70e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-3)" "unprognostic (2.36e-2)" "unprognostic (3.60e-1)" "unprognostic (5.56e-2)" "unprognostic (1.11e-3)" 7.4 9.0 6.3 4.9 21.9 2.3 7.8 11.4 13.7 8.0 6.3 24.3 6.2 5.6 6.4 6.6 13.5 9.0 5.1 12.0 8.1 7.9 8.0 5.6 7.0 5.1 34.0 7.2 7.4 5.9 13.6 7.9 8.2 25.4 8.9 7.9 4.4 8.0 9.6 14.3 10.3 5.1 11.6 75.0 4.6 5.7 9.0 22.2 4.7 5.6 5.8 7.3 7.4 7.8 2.4 6.4 12.3 10.3 2.8 8.8 5.3 18.3 13.4 10.4 5.9 6.7 5.9 7.6 10.6 7.8 12.0 12.4 7.1 7.6 3.1 6.1 11.2 12.2 25.0 8.3 9.9 4.4 7.0 12.4 3.6 10.3 4.4 4.2 17.2 5.0 7.2 5.2 2.8 10.0 6.7 4.5 7.0 12.1 6.4 7.0 4.5 13.6 6.3 9.7 3.9 8.3 6.8 6.6 6.6 6.6 13.0 14.4 12.0 7.4 7.9 8.7 18.0 3.9 6.8 2.3 2.6 3.2 10.1 5.5 20.1 12.3 10.3 9.2 3.6 8.6 8.8 2.4 5.5 4.3 6.4 1.9 4.5 3.3 2.7 2.8 4.3 4.9 5.1 5.3 6.3 21.9 11.4 13.7 8.1 7.9 34.0 7.2 25.4 22.2 FOLH1 "FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA" ENSG00000086205 "Folate hydrolase 1" Q04609 11 49146635-49208670 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.7;intestine: 111.2;prostate: 33.8" "Cell line enhanced" "Detected in some" "HAP1: 5.3;RPMI-8226: 3.7;SK-BR-3: 4.4;TIME: 2.8;WM-115: 5.3" "Cancer enriched" "Detected in many" 27 "prostate cancer: 142.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001451, HPA010593" Enhanced "CAB001451: AB_563979, HPA010593: AB_1079685" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "prognostic favourable (5.24e-5)" "unprognostic (2.55e-1)" "unprognostic (8.31e-2)" "prognostic favourable (4.25e-4)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.67e-3)" "unprognostic (2.13e-2)" "unprognostic (2.72e-1)" "prognostic unfavourable (1.30e-6)" "unprognostic (4.81e-2)" "unprognostic (7.27e-2)" "unprognostic (4.74e-3)" "unprognostic (4.04e-1)" 1.2 1.0 10.4 0.9 16.4 0.8 2.5 1.4 12.7 1.4 67.6 37.7 0.0 111.2 1.3 0.8 1.2 2.1 5.0 0.7 16.9 8.7 6.1 15.7 1.1 0.9 19.0 9.1 1.0 0.7 0.7 0.4 0.7 17.7 33.8 0.8 0.6 20.7 0.8 0.6 1.2 61.1 1.0 33.0 1.5 1.0 0.9 16.2 0.0 1.0 0.0 0.8 1.2 0.5 0.9 0.1 0.3 0.8 1.4 1.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.6 0.0 0.2 5.3 0.5 0.0 1.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 1.0 0.0 0.3 0.3 3.7 0.0 0.0 0.4 1.6 0.0 4.4 1.0 1.0 0.0 2.8 0.2 2.7 0.4 0.3 0.1 0.5 0.1 0.0 0.9 5.3 0.1 0.8 0.3 0.9 0.6 0.2 0.6 1.2 0.5 0.0 0.9 0.7 0.3 0.2 1.4 0.5 0.1 0.4 0.0 10.4 16.4 1.4 12.7 16.9 8.7 19.0 9.1 17.7 16.2 FPGS ENSG00000136877 "Folylpolyglutamate synthase" Q05932 9 127794597-127814327 "Enzymes, Predicted intracellular proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050488 Approved "Intracellular and membrane" "HPA050488: " "unprognostic (6.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "prognostic favourable (9.08e-4)" "unprognostic (1.25e-1)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (6.25e-2)" "unprognostic (2.63e-1)" "unprognostic (1.16e-1)" "unprognostic (6.97e-2)" "unprognostic (1.76e-1)" "unprognostic (8.54e-3)" "unprognostic (2.61e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" 18.2 25.0 6.0 17.4 7.1 14.8 18.9 7.9 6.9 13.9 16.6 9.2 16.6 9.3 16.8 19.2 12.2 17.1 20.0 19.2 6.1 5.9 12.5 44.0 14.9 25.6 8.1 6.6 41.3 24.0 6.6 8.9 6.7 7.7 12.8 6.3 9.9 12.3 18.9 30.4 7.9 10.3 12.6 5.4 17.6 12.4 10.1 7.7 13.6 11.1 15.2 16.0 14.7 9.2 15.5 19.9 1.0 11.8 20.4 21.1 10.2 13.5 9.4 5.4 11.5 8.4 9.2 16.7 10.8 12.8 13.8 10.5 9.7 22.0 16.8 14.1 14.5 25.6 6.7 14.7 4.5 18.3 8.7 13.0 11.8 11.8 20.1 24.0 11.2 12.9 8.4 13.1 17.5 16.4 14.7 10.9 14.0 17.1 20.9 17.9 15.6 28.8 43.5 9.0 29.2 19.8 10.9 8.1 13.8 31.0 15.1 2.1 9.1 10.2 24.7 7.1 10.2 20.7 21.4 12.1 5.2 13.5 15.5 11.2 10.3 0.1 7.8 1.0 21.1 11.8 18.9 12.2 12.6 18.2 15.6 15.5 10.4 13.7 0.4 20.4 11.6 19.9 13.1 10.2 6.0 7.1 7.9 6.9 6.1 5.9 8.1 6.6 7.7 7.7 FPGT GFPP ENSG00000254685 "Fucose-1-phosphate guanylyltransferase" O14772 1 74198212-74234086 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072331 Uncertain Vesicles Vesicles "HPA072331: " "unprognostic (1.53e-1)" "unprognostic (1.94e-1)" "unprognostic (8.18e-3)" "unprognostic (4.32e-2)" "unprognostic (5.14e-2)" "unprognostic (2.46e-1)" "prognostic unfavourable (2.30e-4)" "unprognostic (1.86e-1)" "unprognostic (5.14e-2)" "unprognostic (2.58e-1)" "unprognostic (7.59e-2)" "unprognostic (1.33e-1)" "unprognostic (3.59e-3)" "unprognostic (1.44e-1)" "unprognostic (7.88e-2)" "unprognostic (3.53e-2)" "unprognostic (1.91e-1)" 14.6 11.6 10.9 9.1 12.6 3.4 13.0 19.0 15.8 15.9 11.7 13.0 7.5 11.5 17.7 11.1 15.7 15.4 13.3 12.8 10.9 7.1 15.9 13.7 10.8 8.0 15.5 10.6 14.1 10.2 14.2 27.7 10.6 14.4 11.1 11.3 10.6 11.7 9.1 15.7 12.0 12.0 11.8 16.3 11.0 12.3 8.7 13.9 6.6 20.0 6.8 9.2 17.9 12.9 4.3 9.2 15.2 14.9 3.8 5.4 7.4 9.2 7.7 5.8 8.5 13.5 12.7 8.7 12.2 8.1 8.4 10.0 4.3 7.0 5.7 15.1 7.2 7.8 10.4 11.1 13.4 11.5 4.4 12.9 9.3 7.2 11.3 9.8 9.9 10.4 14.5 8.4 4.0 8.7 13.2 6.8 13.2 2.4 5.4 2.0 6.3 7.0 5.8 13.6 8.0 7.4 6.7 6.1 6.1 9.0 13.2 14.0 15.9 11.2 7.8 3.7 7.1 20.2 9.2 7.5 5.3 7.6 15.0 9.7 12.5 12.0 14.9 15.2 4.3 14.5 5.0 3.6 4.4 3.9 9.2 4.3 4.9 4.4 4.4 3.8 12.5 0.9 5.4 7.4 10.9 12.6 19.0 15.8 10.9 7.1 15.5 10.6 14.4 13.9 FRK "GTK, PTK5, RAK" ENSG00000111816 "Fyn related Src family tyrosine kinase" P42685 6 115931149-116060758 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.4" "Cell line enhanced" "Detected in many" "RT4: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB025217, HPA030479" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB025217: , HPA030479: " "unprognostic (7.70e-3)" "unprognostic (1.99e-2)" "unprognostic (1.11e-1)" "unprognostic (4.68e-3)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (4.23e-2)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (7.54e-2)" "prognostic favourable (9.66e-7)" "unprognostic (1.52e-2)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.10e-1)" 1.5 2.2 0.8 3.0 1.3 1.3 2.6 0.5 0.8 6.4 21.4 0.2 10.2 6.8 1.6 9.0 10.5 2.8 7.3 3.3 1.2 0.8 23.7 19.6 5.6 0.6 1.5 0.5 2.4 5.9 0.3 3.8 2.7 0.8 4.1 5.5 0.8 9.2 6.1 2.9 2.0 41.4 2.5 2.4 1.0 5.5 1.8 0.5 1.2 1.0 5.2 7.4 5.0 3.6 2.2 1.2 3.8 1.2 1.4 2.3 0.3 3.2 5.3 0.8 1.3 0.4 0.4 1.0 0.8 0.2 0.1 0.1 4.1 5.1 1.3 4.9 0.8 7.7 0.4 1.5 0.2 4.4 0.5 1.8 4.6 3.5 0.3 1.2 1.1 0.3 2.2 0.5 0.6 0.3 0.9 3.3 1.3 1.8 1.0 0.8 1.4 0.9 1.5 4.6 1.6 6.5 10.1 1.1 1.2 1.1 6.8 0.7 2.1 1.0 1.3 1.5 1.6 1.2 0.8 5.0 3.5 2.3 1.5 0.8 1.0 3.2 1.0 1.0 1.9 0.6 2.3 1.1 1.4 1.7 0.4 2.2 1.1 1.4 3.8 1.4 1.2 1.2 1.0 0.3 0.8 1.3 0.5 0.7 1.2 0.8 1.5 0.5 0.8 0.5 FTCD ENSG00000160282 "Formimidoyltransferase cyclodeaminase" O95954 21 46136262-46155567 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" "Lyase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 126.8" "Cell line enriched" "Detected in some" 29 "Hep G2: 44.4" "Cancer enriched" "Detected in some" 8 "liver cancer: 87.3" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "T-reg: 2.5" "Lineage enriched" "Detected in single" 25 "T-cells: 2.5" "HPA020073, HPA030928, HPA030929, HPA036114" Enhanced Approved "Plasma membrane,Cytosol" 580000 Cytosol "Plasma membrane" "HPA020073: AB_1849005, HPA030928: AB_2673664, HPA030929: AB_2673665, HPA036114: AB_2674947" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-5)" "unprognostic (2.90e-2)" "unprognostic (1.13e-1)" "unprognostic (2.96e-1)" "prognostic favourable (1.70e-4)" "unprognostic (1.85e-1)" "unprognostic (2.67e-1)" "unprognostic (1.99e-1)" "prognostic favourable (6.78e-5)" "unprognostic (1.80e-1)" "prognostic favourable (5.78e-4)" "unprognostic (3.80e-2)" "unprognostic (3.60e-1)" "unprognostic (9.37e-2)" "unprognostic (2.10e-1)" 0.2 0.0 0.6 0.2 1.6 0.0 0.2 0.2 0.7 0.2 0.3 0.2 0.2 0.3 0.2 2.0 0.2 0.0 0.2 0.2 0.5 0.4 25.9 126.8 0.2 0.2 0.4 0.2 0.2 1.0 0.0 0.2 0.2 0.2 0.3 0.0 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.2 0.2 0.1 1.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 44.4 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 2.5 0.1 0.6 1.6 0.2 0.7 0.5 0.4 0.4 0.2 0.2 0.2 FTH1 "FHC, FTH, FTHL6, PIG15, PLIF" ENSG00000167996 "Ferritin heavy chain 1" P02794 11 61959718-61967660 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Iron storage" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 756.2" "Cell line enhanced" "Detected in all" "ASC diff: 547.1;HHSteC: 570.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 756.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008623 Approved Approved Microtubules 9000000 Microtubules "CAB008623: " "unprognostic (7.15e-2)" "unprognostic (1.52e-2)" "unprognostic (2.27e-1)" "unprognostic (2.00e-2)" "unprognostic (2.53e-1)" "prognostic unfavourable (7.56e-5)" "prognostic unfavourable (6.18e-4)" "unprognostic (3.08e-2)" "unprognostic (2.48e-2)" "unprognostic (6.65e-2)" "unprognostic (2.44e-2)" "unprognostic (8.13e-2)" "prognostic unfavourable (5.20e-5)" "unprognostic (2.99e-1)" "unprognostic (4.89e-2)" "unprognostic (3.44e-1)" "unprognostic (5.83e-2)" 155.1 118.0 177.6 138.9 92.6 162.0 302.9 38.5 163.7 104.2 142.4 97.8 72.0 72.2 81.6 102.4 88.8 70.6 83.5 236.1 124.7 91.2 113.5 128.2 297.3 394.0 118.5 110.6 81.7 150.8 49.7 46.7 70.1 77.5 60.9 138.5 79.5 180.5 65.1 124.1 42.5 110.0 140.0 182.1 84.4 81.0 67.8 88.2 58.5 100.3 64.1 48.9 106.7 94.0 69.5 163.3 756.2 424.5 30.7 69.2 284.2 64.4 181.0 27.6 73.0 547.1 265.0 152.3 59.1 254.1 60.4 61.0 21.9 89.5 7.5 375.8 170.2 110.4 24.6 48.9 39.2 30.7 12.1 37.5 250.9 142.9 570.0 17.6 59.0 358.9 240.3 120.5 226.6 75.5 55.9 86.0 210.8 87.2 19.7 28.8 47.2 306.1 19.6 34.1 53.6 308.6 175.5 23.5 29.7 203.3 22.4 96.2 39.8 23.7 84.1 188.8 45.2 83.5 37.1 14.9 51.2 23.1 257.4 7.8 44.9 401.9 297.7 247.4 40.8 367.6 40.2 68.6 58.3 40.4 163.3 69.5 49.3 38.2 756.2 30.7 424.5 121.2 69.2 284.2 177.6 92.6 38.5 163.7 124.7 91.2 118.5 110.6 77.5 88.2 FTSJ1 "CDLIV, JM23, MRX44, MRX9, SPB1, TRM7, TRMT7" ENSG00000068438 "FtsJ RNA methyltransferase homolog 1" Q9UET6 X 48476021-48486364 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002718 Approved Approved Cytosol Cytosol "HPA002718: AB_1078914" "unprognostic (2.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.44e-1)" "unprognostic (3.37e-1)" "unprognostic (2.13e-1)" "unprognostic (6.77e-2)" "prognostic unfavourable (1.74e-5)" "unprognostic (1.95e-2)" "unprognostic (2.39e-1)" "unprognostic (3.96e-3)" "unprognostic (2.06e-3)" "unprognostic (7.82e-2)" "prognostic unfavourable (5.24e-10)" "unprognostic (2.61e-1)" "unprognostic (1.49e-1)" "unprognostic (1.56e-2)" "unprognostic (1.23e-1)" 17.6 19.4 12.3 18.2 21.6 18.4 17.1 18.7 21.2 23.3 11.7 13.6 20.8 10.7 18.5 12.6 19.0 15.9 12.8 15.0 9.9 10.3 15.9 21.3 16.9 22.9 13.6 9.2 17.4 36.6 13.9 16.2 11.3 14.9 13.3 10.6 12.4 20.8 18.6 17.3 18.0 12.0 16.6 11.0 19.6 17.8 14.6 15.2 17.2 20.0 24.8 18.6 17.3 17.2 17.1 16.8 10.7 16.1 15.9 26.9 15.1 25.5 17.7 6.8 26.9 9.7 10.2 11.1 12.6 12.1 18.4 14.6 10.5 35.9 14.9 9.4 19.2 17.3 13.5 44.3 8.3 11.3 12.7 9.5 22.4 11.8 27.7 13.0 24.0 9.5 22.4 23.1 22.8 12.8 8.0 12.5 23.8 14.5 16.8 9.3 15.3 30.4 13.7 22.2 30.9 17.3 8.6 9.2 9.1 20.0 11.0 9.2 12.6 7.5 12.5 14.6 19.8 30.3 15.3 16.9 13.1 10.7 32.2 24.5 15.2 9.2 14.1 10.7 21.9 16.1 26.9 17.1 18.9 22.1 16.8 16.9 17.3 21.9 2.0 15.9 15.1 11.6 17.5 15.1 12.3 21.6 18.7 21.2 9.9 10.3 13.6 9.2 14.9 15.2 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868294 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced "Intracellular and membrane" 65000000 "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favourable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favourable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 15.8 18.0 4.6 24.1 7.1 0.9 8.9 4.2 8.1 13.1 30.2 6.9 28.4 20.4 9.9 35.7 8.7 12.7 22.6 15.0 4.7 6.4 28.9 39.3 20.7 66.7 4.8 4.7 19.4 15.5 12.2 10.9 31.9 8.0 15.2 33.5 13.8 22.6 18.5 6.9 6.6 42.3 7.4 7.1 32.3 14.8 15.6 2.9 11.6 27.3 8.0 25.1 23.6 7.8 8.3 15.2 16.8 34.8 14.4 9.9 19.0 5.2 3.6 0.7 10.9 1.4 0.1 3.8 5.6 11.7 5.9 11.1 4.8 56.3 7.9 14.2 7.1 3.2 5.2 12.0 7.8 5.6 8.7 6.5 3.2 10.8 5.0 0.6 21.8 5.4 6.8 2.1 2.8 2.3 3.0 0.1 7.0 5.7 1.6 5.8 1.8 5.7 8.9 0.0 8.6 22.0 13.6 3.7 3.6 16.2 6.3 8.5 4.7 2.6 0.6 2.0 3.2 13.4 1.9 9.9 10.0 2.8 5.0 19.7 3.2 13.7 34.8 16.8 9.9 34.5 8.5 8.3 7.2 8.4 15.2 4.7 7.0 8.2 4.3 14.4 28.7 8.8 7.0 19.0 4.6 7.1 4.2 8.1 4.7 6.4 4.8 4.7 8.0 2.9 FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494811-143511690 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" 53000000 "HPA031659: AB_10600661, HPA031661: AB_10601681" "unprognostic (1.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "prognostic unfavourable (2.70e-9)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (7.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-3)" "unprognostic (9.18e-2)" "unprognostic (2.69e-1)" "unprognostic (7.25e-2)" "unprognostic (5.07e-2)" 22.6 32.6 10.3 14.2 16.2 11.6 24.1 6.2 11.4 18.5 21.2 17.6 23.1 22.0 17.9 24.8 11.9 17.2 25.0 25.6 11.6 11.8 34.1 45.7 21.7 30.0 20.4 8.7 21.9 32.6 52.3 14.4 40.7 16.9 12.0 28.4 21.4 18.9 24.5 6.7 9.3 29.5 14.6 18.5 20.3 20.4 11.0 16.1 3.6 17.9 8.7 10.3 16.7 15.0 4.1 22.9 9.3 29.3 9.7 6.7 14.9 23.1 13.6 11.9 21.5 17.6 34.7 22.5 21.9 23.6 27.1 46.1 25.9 23.3 0.0 16.4 29.4 0.1 5.9 2.9 37.7 20.8 22.8 7.8 25.4 39.1 25.5 0.0 4.0 18.5 17.4 24.2 10.5 27.5 27.6 12.2 30.5 27.4 0.0 18.1 15.4 18.8 0.0 24.9 17.1 32.2 14.5 9.0 5.9 24.1 16.2 19.7 7.9 19.1 16.1 16.2 13.7 40.3 42.1 4.5 4.9 0.1 18.7 14.3 5.5 9.3 29.3 8.7 4.9 28.8 5.6 4.1 3.6 4.1 22.9 2.5 1.6 3.0 2.0 9.7 20.0 3.5 6.7 14.9 10.3 16.2 6.2 11.4 11.6 11.8 20.4 8.7 16.9 16.1 FUK FLJ39408 ENSG00000157353 Fucokinase Q8N0W3 16 70454421-70480274 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041971 Approved Approved Vesicles Vesicles "HPA041971: AB_10795648" "unprognostic (4.55e-1)" "unprognostic (3.21e-1)" "unprognostic (1.73e-2)" "unprognostic (3.95e-2)" "unprognostic (3.79e-2)" "unprognostic (2.64e-2)" "unprognostic (8.79e-3)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (4.82e-3)" "unprognostic (4.85e-2)" "prognostic favourable (8.91e-4)" "unprognostic (2.49e-2)" "unprognostic (9.68e-2)" "unprognostic (8.89e-2)" "prognostic favourable (8.38e-4)" 6.7 11.3 11.5 9.8 13.2 8.5 7.3 13.9 13.5 7.5 12.1 15.5 15.1 18.5 8.3 11.5 8.2 10.8 9.4 7.2 9.4 7.4 13.1 11.9 8.1 9.1 12.5 12.4 10.5 12.2 17.1 16.4 11.0 9.8 9.1 7.7 12.9 10.8 9.4 9.0 13.0 13.1 6.3 9.3 9.7 12.2 6.1 12.5 7.2 12.0 4.2 11.1 7.6 6.8 4.3 3.2 3.9 4.4 2.9 6.7 2.5 3.0 4.3 2.6 5.6 1.5 1.8 9.7 1.8 2.9 2.4 3.1 3.8 10.1 2.2 8.6 1.7 4.5 1.7 4.4 1.5 4.1 6.2 2.8 7.9 4.4 3.7 3.6 2.1 3.0 5.3 1.8 4.5 4.4 5.4 2.7 1.8 9.7 4.3 8.4 1.6 2.4 6.4 0.6 9.6 6.1 5.4 4.2 5.0 10.1 3.5 5.1 14.8 7.1 4.6 1.9 2.5 4.1 2.0 9.5 4.5 4.5 3.4 3.5 4.2 0.6 4.4 1.8 4.8 2.5 4.1 1.9 4.8 4.8 2.7 4.3 6.7 3.1 3.9 2.9 2.8 3.2 3.2 2.5 11.5 13.2 13.9 13.5 9.4 7.4 12.5 12.4 9.8 12.5 FUOM "C10orf125, FLJ26016, FucM, FucU" ENSG00000148803 "Fucose mutarotase" A2VDF0 10 133355154-133358035 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 68.3" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in all" "liver cancer: 61.0" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039207 Uncertain 2500000 "HPA039207: AB_10795033" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (4.48e-2)" "unprognostic (7.19e-2)" "unprognostic (4.82e-1)" "unprognostic (2.66e-2)" "unprognostic (1.66e-2)" "unprognostic (2.45e-1)" "unprognostic (6.25e-2)" "unprognostic (7.56e-2)" "unprognostic (4.50e-2)" "unprognostic (8.67e-2)" "unprognostic (3.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" "unprognostic (1.65e-1)" 4.9 3.3 1.9 7.1 2.1 2.2 4.5 1.1 2.4 2.2 15.2 2.6 4.9 20.5 2.1 6.3 3.6 2.8 5.8 6.8 1.6 1.3 14.2 68.3 7.5 6.7 2.1 0.9 3.7 6.9 0.8 2.3 2.0 3.0 2.4 2.2 6.7 18.8 3.0 1.9 2.6 28.3 2.4 1.7 9.7 3.0 2.4 1.2 2.8 2.4 3.3 6.1 2.9 2.6 13.0 28.7 2.1 25.6 5.7 6.0 10.1 10.9 3.5 6.8 13.9 1.9 4.9 12.4 8.8 10.3 3.3 4.1 22.1 6.1 0.0 10.3 6.7 0.6 2.4 3.0 0.3 3.9 2.4 10.7 5.3 23.8 10.2 11.8 7.3 4.9 0.1 1.3 0.7 4.5 10.3 14.7 6.8 10.9 1.8 15.8 4.7 1.6 10.3 0.2 6.4 3.7 0.0 0.7 5.4 3.3 10.1 12.1 0.1 18.2 9.0 0.0 9.3 0.0 0.0 7.7 1.2 7.6 2.7 4.9 3.4 0.0 25.6 2.1 6.0 25.6 5.6 12.6 5.4 5.0 20.7 13.0 5.8 5.0 1.2 5.7 5.4 28.7 3.5 10.1 1.9 2.1 1.1 2.4 1.6 1.3 2.1 0.9 3.0 1.2 FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868592-90883458 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "liver: 118.4;placenta: 158.9;salivary gland: 337.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009499 Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" 41000 "Golgi apparatus" Nucleoplasm "CAB009499: AB_2105095" "unprognostic (2.46e-1)" "unprognostic (2.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.30e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-2)" "unprognostic (8.11e-2)" "prognostic unfavourable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (9.92e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (4.52e-3)" "unprognostic (4.57e-2)" "unprognostic (4.46e-2)" "unprognostic (4.27e-3)" "unprognostic (8.20e-2)" 8.3 3.3 3.0 7.5 3.6 16.6 5.9 5.0 4.4 4.1 6.6 2.8 3.5 5.7 4.9 10.8 4.7 4.4 3.9 6.9 3.1 1.8 6.4 118.4 9.5 3.1 2.8 2.7 4.2 22.5 3.8 7.2 158.9 3.5 9.3 2.2 3.0 337.9 4.7 8.7 9.0 5.9 3.1 3.0 8.2 6.0 5.3 2.9 4.8 8.9 5.5 4.1 4.4 4.3 1.5 3.3 10.3 3.3 3.1 1.9 2.0 14.1 8.6 1.9 8.7 14.3 9.2 22.2 17.8 13.6 7.4 5.2 12.6 15.5 0.5 45.9 12.9 25.5 3.9 9.2 1.6 40.7 10.1 24.8 15.5 16.5 7.6 3.4 40.9 10.4 10.4 8.4 3.8 23.6 18.9 2.5 4.9 9.7 1.3 11.2 6.2 2.5 2.2 7.5 3.2 11.5 10.8 3.9 2.6 15.1 8.2 12.6 2.9 9.1 34.7 8.3 17.8 12.7 26.1 4.4 25.1 1.1 15.9 11.2 16.8 7.5 3.3 10.3 1.9 1.1 1.4 1.5 1.2 1.2 2.1 1.0 0.6 0.8 7.4 3.1 0.7 3.3 0.9 2.0 3.0 3.6 5.0 4.4 3.1 1.8 2.8 2.7 3.5 2.9 FUT2 "SE, Se2, SEC2, sej" ENSG00000176920 "Fucosyltransferase 2" Q10981 19 48695971-48705950 "Blood group antigen proteins, Enzymes, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.3;salivary gland: 58.1" "Cell line enriched" "Detected in some" 6 "CAPAN-2: 40.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "cerebellum: 8.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA014402 Uncertain Uncertain "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA014402: AB_1849194" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (2.80e-3)" "unprognostic (4.63e-3)" "unprognostic (2.63e-1)" "prognostic favourable (5.83e-4)" "unprognostic (6.30e-3)" "unprognostic (6.55e-3)" "unprognostic (1.58e-1)" "unprognostic (8.44e-2)" "unprognostic (7.89e-2)" "unprognostic (5.11e-1)" "unprognostic (4.04e-2)" "unprognostic (6.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" 0.4 0.6 0.7 5.3 0.8 0.0 0.8 8.7 1.6 9.3 25.0 0.3 13.9 24.1 1.3 0.1 16.0 1.2 23.3 0.5 0.7 0.7 0.8 0.4 1.1 0.1 0.7 0.1 1.0 7.5 0.0 1.5 0.2 0.7 1.2 10.9 0.1 58.1 14.5 0.5 2.6 41.3 0.4 0.7 0.6 15.8 0.7 0.2 0.5 0.6 16.1 19.3 3.1 5.4 1.7 1.8 3.5 1.0 1.4 2.5 0.6 1.1 1.0 0.2 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.8 40.9 0.3 0.3 0.0 7.2 0.0 0.0 0.0 0.4 0.3 0.4 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.4 0.5 0.9 0.3 0.3 0.3 0.1 1.8 0.0 0.3 2.2 0.3 0.1 0.3 0.0 6.1 0.0 0.1 0.2 0.3 0.3 0.1 0.3 0.2 0.0 0.2 0.2 0.1 3.5 0.8 0.4 2.0 0.7 1.1 1.5 2.3 1.0 0.5 1.7 2.1 0.7 3.4 1.4 1.0 1.8 2.5 0.6 0.7 0.8 8.7 1.6 0.7 0.7 0.7 0.1 0.7 0.2 FUT3 "CD174, LE" ENSG00000171124 "Fucosyltransferase 3 (Lewis blood group)" P21217 19 5842888-5851474 "Blood group antigen proteins, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.6;intestine: 49.3;lymphoid tissue: 38.4" "Group enriched" "Detected in some" 4 "A-431: 30.2;RH-30: 10.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" HPA046966 Supported "HPA046966: " "prognostic unfavourable (6.86e-4)" "unprognostic (2.59e-1)" "unprognostic (1.06e-1)" "unprognostic (9.12e-2)" "unprognostic (8.58e-3)" "unprognostic (1.63e-3)" "unprognostic (3.88e-2)" "unprognostic (2.03e-2)" "unprognostic (4.02e-2)" "unprognostic (3.98e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "prognostic favourable (8.22e-7)" "unprognostic (5.66e-3)" "unprognostic (9.56e-2)" "unprognostic (4.30e-2)" "unprognostic (1.07e-1)" 0.2 0.1 0.2 14.5 0.2 0.0 0.4 0.2 0.2 10.9 40.4 0.2 32.5 18.8 0.4 0.5 53.6 0.7 21.5 0.1 0.2 0.2 3.8 0.9 5.1 0.1 0.2 0.1 0.5 4.7 0.0 0.3 0.6 0.1 1.0 18.1 0.2 27.5 31.6 0.1 1.0 49.3 1.0 0.2 0.1 8.1 1.3 0.1 0.3 0.1 14.9 38.4 2.9 16.1 0.2 1.6 0.8 0.6 0.0 0.5 0.0 30.2 0.0 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.4 0.0 1.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 10.2 1.0 0.0 0.5 0.0 0.1 0.0 4.8 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.8 0.0 0.0 1.6 0.5 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.1 FUT5 FUC-TV ENSG00000130383 "Fucosyltransferase 5" Q11128 19 5865826-5870540 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 3.6" "Cell line enhanced" "Detected in some" "MCF7: 1.8;SH-SY5Y: 2.9;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046966 Uncertain "HPA046966: " "unprognostic (7.72e-2)" "unprognostic (3.59e-1)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" 0.2 0.1 1.0 0.1 0.5 3.6 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.5 0.3 0.3 1.1 0.4 0.3 0.2 1.1 0.1 0.2 0.9 0.2 0.5 0.1 0.3 0.1 0.1 0.1 0.4 0.1 1.2 0.5 0.1 0.1 0.8 0.2 0.1 1.6 0.1 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.0 0.7 0.0 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830610-5839731 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8;intestine: 44.4;lymphoid tissue: 33.9;salivary gland: 37.0" "Group enriched" "Detected in some" 7 "Hep G2: 14.6;RPMI-8226: 5.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basophil: 3.7;neutrophil: 1.2;NK-cell: 2.1" "Group enriched" "Detected in many" 7 "granulocytes: 3.7;NK-cells: 2.1" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Golgi apparatus" "HPA043707: , HPA046966: " "unprognostic (3.65e-2)" "unprognostic (3.00e-3)" "unprognostic (2.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.35e-2)" "prognostic favourable (2.12e-4)" "unprognostic (8.02e-2)" "unprognostic (6.68e-3)" "unprognostic (4.01e-2)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (4.94e-2)" "prognostic favourable (3.17e-8)" "unprognostic (1.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" 0.2 0.2 0.2 7.2 0.2 0.1 0.8 0.2 0.2 9.2 26.4 0.0 9.5 15.6 0.7 7.6 40.8 0.6 25.4 0.2 0.2 0.2 27.2 6.5 1.3 0.2 0.2 0.0 0.2 2.2 0.0 0.8 0.0 0.0 0.3 6.9 0.0 37.0 19.1 0.2 0.2 44.4 0.2 0.2 0.2 2.8 0.3 0.0 0.0 0.2 16.4 33.9 0.2 12.4 0.4 0.3 3.7 0.3 2.1 0.3 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.2 14.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 5.4 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.3 0.1 3.7 0.3 0.4 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.4 0.3 0.2 1.2 2.1 0.1 0.3 0.1 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 FUT8 ENSG00000033170 "Fucosyltransferase 8" Q9BYC5 14 65410592-65744121 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 13.5;NK-cells: 12.0;T-cells: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017129, HPA040863, HPA043410" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB017129: , HPA040863: , HPA043410: " "unprognostic (1.67e-1)" "unprognostic (1.63e-1)" "unprognostic (3.28e-2)" "unprognostic (1.65e-3)" "unprognostic (2.10e-1)" "unprognostic (5.61e-2)" "unprognostic (1.41e-1)" "unprognostic (8.81e-2)" "unprognostic (2.00e-2)" "unprognostic (1.33e-3)" "unprognostic (8.09e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-3)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" 7.2 7.6 16.2 12.0 21.1 3.3 9.4 24.1 18.1 6.7 9.8 29.1 16.1 15.4 8.7 5.0 6.5 14.0 10.1 5.2 19.8 12.9 6.2 2.9 7.0 11.2 20.5 11.2 7.2 10.5 6.2 5.2 18.8 17.3 5.4 10.4 7.1 33.7 13.7 3.5 4.9 15.1 9.5 39.8 8.5 27.6 13.1 23.6 8.4 7.5 2.4 15.2 14.4 5.6 13.5 2.2 0.5 1.7 12.0 8.2 2.5 34.9 6.9 3.3 30.7 14.8 11.2 20.8 11.2 17.2 7.8 8.7 5.4 12.9 9.3 9.6 11.1 2.6 7.9 3.1 12.0 34.5 3.4 9.4 2.5 7.0 7.6 2.1 7.7 28.1 2.0 10.8 5.1 19.8 3.4 7.9 5.6 18.0 9.9 5.1 4.5 24.2 6.8 2.9 5.3 14.0 9.8 7.1 5.3 6.0 2.8 2.4 2.8 3.4 43.1 10.3 11.0 4.5 9.1 15.9 6.0 22.2 20.8 3.7 3.2 0.5 1.7 0.5 3.5 0.6 3.5 13.5 5.6 5.1 2.2 6.8 6.1 6.0 0.2 12.0 1.1 2.2 8.2 2.5 16.2 21.1 24.1 17.3 19.8 12.9 20.5 11.2 17.3 23.6 FXN "CyaY, FA, FARR, FRDA, X25" ENSG00000165060 Frataxin Q16595 9 69035259-69120427 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transporters" "Heme biosynthesis, Ion transport, Iron storage, Iron transport, Transport" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022164, HPA068304" Supported Supported Mitochondria,Cytosol Mitochondria Cytosol "CAB022164: , HPA068304: " "unprognostic (3.38e-2)" "unprognostic (1.54e-1)" "unprognostic (7.47e-2)" "unprognostic (2.37e-3)" "unprognostic (4.08e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (4.19e-2)" "unprognostic (2.53e-1)" "unprognostic (2.71e-3)" "unprognostic (1.10e-1)" "unprognostic (9.06e-2)" "unprognostic (1.67e-1)" "unprognostic (4.74e-2)" 8.7 19.9 10.8 9.1 9.8 21.9 11.8 13.9 11.0 8.3 9.3 12.3 11.6 6.6 12.4 11.7 9.2 9.6 7.2 20.2 8.7 10.1 10.2 40.2 9.5 12.8 11.7 8.5 16.8 25.9 18.8 8.6 8.4 10.5 9.9 11.6 12.1 11.9 13.6 25.1 5.2 7.2 16.6 8.9 12.9 9.2 13.3 9.7 3.7 11.1 9.5 9.6 10.5 7.9 15.8 17.7 2.0 18.5 24.2 28.3 19.1 11.2 9.6 15.7 7.5 7.2 10.7 15.2 8.2 7.2 12.5 9.7 5.1 7.3 20.2 6.3 8.5 12.4 18.5 18.7 15.8 23.6 21.1 28.5 6.3 37.5 12.3 20.8 12.4 11.8 15.1 12.5 13.6 16.7 21.3 19.8 11.6 11.0 5.9 9.1 21.2 19.1 14.0 10.8 13.8 14.4 9.4 12.1 5.4 8.4 5.5 8.5 6.2 6.4 9.9 8.2 14.3 10.7 11.8 5.6 4.8 12.0 3.8 17.2 8.2 2.0 16.7 0.1 21.5 18.5 16.3 15.8 22.0 21.2 17.7 10.3 28.3 27.1 0.8 24.2 14.1 15.0 17.0 19.1 10.8 9.8 13.9 11.0 8.7 10.1 11.7 8.5 10.5 9.7 FYN "MGC45350, SLK, SYN" ENSG00000010810 "FYN proto-oncogene, Src family tyrosine kinase" P06241 6 111660332-111873452 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 103.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 17 "NK-cells: 15.3;T-cells: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005034, CAB018387, HPA023887, HPA063770" Approved Enhanced "Plasma membrane,Cytosol" 2000000 "Plasma membrane" Cytosol "CAB005034: AB_562117, CAB018387: AB_627642, HPA023887: AB_1849226, HPA063770: " "unprognostic (8.62e-3)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "prognostic favourable (1.84e-4)" "unprognostic (4.60e-2)" "unprognostic (2.89e-2)" "unprognostic (2.92e-1)" "prognostic favourable (4.78e-4)" "unprognostic (1.43e-1)" "prognostic unfavourable (1.43e-4)" "unprognostic (6.95e-2)" "unprognostic (3.10e-1)" "unprognostic (6.62e-3)" "unprognostic (2.40e-1)" 29.1 7.2 49.2 29.0 38.4 16.3 18.1 33.9 62.1 25.7 12.1 33.7 4.1 10.1 21.8 21.4 10.2 32.0 19.4 21.2 39.4 34.0 9.5 12.2 25.2 57.2 35.7 23.1 18.6 4.4 15.0 12.5 17.7 25.6 9.6 10.0 11.0 6.4 8.4 7.0 16.5 19.0 24.2 30.9 39.8 15.4 10.1 31.3 34.8 27.5 5.6 38.5 22.6 19.3 1.6 1.7 0.7 1.5 15.3 43.2 10.7 1.9 0.2 34.2 5.7 26.2 16.1 0.6 5.4 17.1 4.6 8.3 0.2 0.3 3.8 3.5 10.4 0.2 4.8 7.5 9.1 0.1 12.6 10.5 2.5 0.5 15.5 3.5 3.6 15.4 11.3 17.4 14.9 18.8 0.8 26.8 16.4 0.2 16.7 3.2 4.9 3.4 5.3 4.6 0.2 0.0 1.7 24.0 9.7 1.0 0.4 22.8 0.2 10.6 11.9 14.0 2.6 103.1 3.4 3.8 3.5 5.9 26.4 8.2 24.3 0.2 1.5 0.0 34.1 1.2 43.2 1.1 21.2 37.5 1.7 1.6 7.0 18.7 0.7 15.3 0.9 1.0 17.6 10.7 49.2 38.4 33.9 35.3 39.4 34.0 35.7 23.1 25.6 31.3 G2E3 "FLJ20333, KIAA1333, PHF7B" ENSG00000092140 "G2/M-phase specific E3 ubiquitin protein ligase" Q7L622 14 30559123-30620063 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 39.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001601 Approved Approved "Golgi apparatus,Vesicles,Cytosol" Cytosol "Golgi apparatus, Vesicles" "HPA001601: AB_1079198" "unprognostic (4.75e-2)" "unprognostic (6.31e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (9.10e-2)" "unprognostic (3.99e-2)" "unprognostic (5.44e-6)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (1.86e-1)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (2.32e-2)" "unprognostic (2.12e-2)" 7.6 5.1 5.6 7.6 14.2 8.5 6.6 10.8 10.4 8.1 5.8 5.8 4.2 5.9 8.5 4.8 7.0 5.4 4.5 4.9 6.7 5.2 5.4 5.5 5.4 8.6 7.3 4.9 7.1 5.7 6.0 10.9 6.9 7.6 6.0 6.1 5.3 5.9 7.1 5.2 6.1 5.8 6.7 7.1 7.9 5.4 39.6 8.8 20.9 7.3 4.8 9.5 6.0 8.3 11.5 8.1 16.5 12.5 7.9 12.4 5.0 20.8 9.5 21.3 9.8 6.9 8.5 18.0 19.6 7.1 11.9 13.4 9.2 12.7 17.5 6.3 10.7 17.6 20.4 11.2 24.2 14.4 8.3 9.6 10.4 16.9 6.2 18.5 12.2 5.3 4.5 9.5 21.7 14.0 11.8 14.6 16.6 12.1 12.4 4.6 17.8 16.7 11.4 0.0 4.8 7.0 13.0 18.1 12.2 15.8 10.7 4.5 12.2 6.3 10.4 12.7 13.6 9.3 12.8 8.4 24.6 21.0 3.8 9.3 18.8 16.5 7.5 14.1 9.6 9.7 12.4 10.8 9.4 7.7 6.4 11.5 12.0 10.1 6.8 7.9 12.5 8.1 7.3 5.0 5.6 14.2 10.8 10.4 6.7 5.2 7.3 4.9 7.6 8.8 G3BP1 "G3BP, HDH-VIII" ENSG00000145907 "G3BP stress granule assembly factor 1" Q13283 5 151771045-151812785 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, Transport" "DNA-binding, Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004052, CAB037068" Supported Supported Cytosol 150000 Cytosol "CAB037068: AB_1840864, HPA004052: AB_1849348" "unprognostic (1.31e-1)" "unprognostic (3.94e-2)" "unprognostic (1.19e-3)" "unprognostic (1.28e-2)" "unprognostic (1.05e-1)" "unprognostic (3.09e-2)" "unprognostic (1.03e-3)" "unprognostic (1.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.36e-1)" "unprognostic (2.06e-3)" "unprognostic (1.23e-2)" "prognostic unfavourable (3.33e-4)" "unprognostic (1.97e-1)" "unprognostic (1.33e-1)" "unprognostic (2.11e-2)" "unprognostic (3.88e-2)" 36.7 27.5 21.1 29.1 23.7 12.2 29.7 24.3 21.4 28.5 23.4 27.7 19.6 18.1 29.9 19.3 40.7 26.5 20.7 24.8 21.7 21.2 30.7 44.1 25.9 36.8 31.8 16.7 38.2 30.6 29.9 29.9 27.9 24.9 24.5 27.2 22.6 24.1 19.7 66.4 25.3 22.8 27.0 27.4 28.9 20.6 27.4 25.8 57.1 28.9 37.0 42.3 27.7 34.8 25.6 19.9 19.5 19.1 29.4 40.0 32.1 37.4 29.3 36.1 15.8 46.0 24.9 41.7 37.2 33.8 48.0 57.0 53.8 48.6 69.9 54.7 34.5 35.6 54.5 72.2 63.0 19.3 26.2 43.2 27.1 36.0 26.2 54.1 28.6 24.9 39.4 41.7 41.4 39.5 33.8 34.5 47.0 20.1 45.6 24.0 40.3 30.0 41.8 45.6 33.3 31.5 37.2 34.1 24.7 35.2 51.3 53.8 41.0 30.1 43.1 34.7 40.4 32.8 67.5 21.5 29.6 55.0 26.1 41.6 62.6 19.5 13.9 13.0 25.7 19.1 40.0 25.6 34.4 28.7 18.0 21.9 33.0 32.9 6.1 29.4 16.8 19.9 34.0 32.1 21.1 23.7 24.3 21.4 21.7 21.2 31.8 16.7 24.9 25.8 G6PC "G6PT, GSD1a" ENSG00000131482 "Glucose-6-phosphatase catalytic subunit" P35575 17 42900797-42913369 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 305.4" "Cell line enhanced" "Detected in some" "RH-30: 2.2" "Cancer enriched" "Detected in some" 72 "liver cancer: 151.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052324 Enhanced "HPA052324: " "unprognostic (4.23e-2)" "unprognostic (1.49e-2)" "prognostic favourable (5.42e-5)" "unprognostic (8.37e-2)" "prognostic favourable (3.79e-5)" "unprognostic (4.79e-2)" "unprognostic (6.46e-2)" "unprognostic (2.56e-3)" 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 5.0 0.0 0.0 5.8 0.1 0.0 0.1 0.1 1.9 0.1 0.1 0.1 23.7 305.4 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 33.7 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 2.2 0.5 1.1 0.2 0.5 0.4 0.0 0.4 0.2 0.2 0.5 0.6 0.0 0.7 0.2 0.2 0.0 0.1 0.2 0.3 0.7 0.2 0.2 0.4 0.0 0.0 0.2 0.3 0.1 0.1 0.5 0.8 0.0 1.3 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.7 0.0 0.1 0.5 1.1 0.3 0.3 0.6 2.2 0.2 0.1 0.7 0.4 0.6 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.7 0.2 0.9 0.3 1.4 0.2 1.1 0.2 0.1 0.3 0.1 0.2 1.0 0.2 0.2 0.0 2.2 0.4 0.4 1.1 0.5 0.1 0.5 0.4 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 G6PC3 UGRP ENSG00000141349 "Glucose-6-phosphatase catalytic subunit 3" Q9BUM1 17 44070735-44076344 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067052 Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA067052: " "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" "unprognostic (3.61e-1)" "prognostic favourable (1.11e-4)" "unprognostic (1.88e-3)" "unprognostic (3.16e-1)" "prognostic unfavourable (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (2.43e-1)" "unprognostic (1.15e-2)" "unprognostic (2.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.87e-3)" "unprognostic (4.53e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.49e-2)" 25.4 38.1 25.8 15.6 25.4 11.1 23.4 12.9 35.3 25.3 17.8 37.8 28.3 21.1 22.0 50.9 14.4 27.7 20.5 22.2 25.4 37.8 42.8 15.3 18.7 29.8 32.9 21.3 28.1 29.1 38.4 37.7 22.2 34.0 26.1 15.2 37.4 27.7 33.8 22.9 9.9 17.7 17.8 33.1 19.7 18.2 20.7 16.0 18.5 35.1 11.4 14.8 21.4 14.0 5.9 33.4 3.1 19.0 7.2 6.1 6.5 10.0 60.3 21.1 34.0 22.5 16.7 14.8 11.6 23.8 27.1 18.2 24.9 16.4 23.2 16.7 25.8 17.4 16.1 24.7 13.0 11.9 24.7 12.7 40.8 45.4 23.4 11.4 16.2 22.0 11.9 25.7 18.1 22.5 13.1 29.7 20.2 28.1 5.6 17.7 26.4 39.3 11.8 13.2 53.8 36.8 23.8 25.4 22.5 12.8 15.3 14.8 42.3 11.7 22.4 26.9 14.3 7.2 16.1 19.7 14.1 6.6 29.9 10.0 34.1 1.2 15.2 3.1 4.6 19.0 5.6 5.5 3.6 4.4 24.6 5.9 4.6 6.1 0.5 7.2 11.1 33.4 3.5 6.5 25.8 25.4 12.9 35.3 25.4 37.8 32.9 21.3 34.0 16.0 G6PD G6PD1 ENSG00000160211 "Glucose-6-phosphate dehydrogenase" P11413 X 154531391-154547572 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Oxidoreductase "Cancer-related genes, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 83.1" "Cell line enhanced" "Detected in all" "A549: 225.5;MCF7: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 77.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 77.3" "Low region specificity" "Detected in all" "HPA000247, HPA000834" Enhanced Enhanced "Centriolar satellite,Cytosol" 12000000 Cytosol "Centriolar satellite" "HPA000247: AB_1078978, HPA000834: AB_1078977" "unprognostic (1.73e-2)" "unprognostic (1.53e-3)" "unprognostic (1.13e-2)" "unprognostic (1.02e-1)" "unprognostic (7.78e-2)" "unprognostic (4.34e-2)" "prognostic unfavourable (9.45e-13)" "unprognostic (2.78e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-1)" "unprognostic (3.66e-1)" "unprognostic (2.89e-3)" "unprognostic (2.83e-1)" "unprognostic (1.94e-1)" "unprognostic (1.47e-1)" "unprognostic (7.25e-2)" 21.9 29.4 10.4 15.6 10.7 51.4 18.2 8.4 14.7 12.2 7.5 13.6 4.8 7.2 14.0 13.2 29.0 11.0 24.7 10.1 8.8 10.1 15.4 3.7 20.8 31.0 10.3 8.0 19.8 7.9 5.9 20.7 9.2 10.9 11.3 7.3 17.8 13.9 8.6 4.4 11.3 7.3 17.5 11.1 20.3 9.9 83.1 9.5 22.5 24.6 44.8 25.7 24.1 19.0 3.6 7.6 77.3 16.2 12.7 10.3 11.8 15.4 225.5 4.6 17.8 19.5 26.7 4.1 10.8 31.0 11.0 19.1 10.3 5.8 10.0 16.8 24.7 13.8 7.2 18.3 5.7 10.2 5.0 10.6 51.0 23.2 38.2 10.6 36.4 12.9 5.4 21.6 4.6 22.9 6.3 4.4 19.9 85.5 6.8 7.6 3.3 16.7 6.7 2.6 10.9 33.2 19.3 4.7 5.9 10.8 42.1 9.0 6.3 8.9 27.2 7.0 24.7 9.7 16.6 5.3 6.9 17.1 19.4 7.0 14.3 29.3 16.2 77.3 10.3 13.6 6.6 3.4 2.7 7.4 7.6 3.6 3.5 5.9 27.1 12.7 11.1 3.5 3.5 11.8 10.4 10.7 8.4 14.7 8.8 10.1 10.3 8.0 10.9 9.5 GAA ENSG00000171298 "Glucosidase alpha, acid" P10253 17 80101556-80119879 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 23.8;eosinophil: 8.4;intermediate monocyte: 20.0;myeloid DC: 15.6;neutrophil: 10.8;non-classical monocyte: 24.7" "Group enriched" "Detected in all" 9 "dendritic cells: 15.6;granulocytes: 10.8;monocytes: 24.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026970, HPA029126" Enhanced 3000000 "HPA026970: AB_2672065, HPA029126: AB_2672918" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "prognostic unfavourable (7.66e-4)" "unprognostic (2.94e-2)" "unprognostic (1.14e-2)" "unprognostic (7.96e-2)" "unprognostic (2.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.29e-2)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (7.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.78e-2)" "unprognostic (1.18e-1)" 27.5 19.6 13.8 17.0 14.8 11.3 18.6 14.3 23.0 14.9 16.5 23.4 21.7 19.4 20.1 50.9 13.9 18.2 23.5 21.4 13.5 17.6 27.9 44.2 34.0 30.2 18.1 16.1 14.6 29.4 28.8 24.7 84.1 14.9 22.3 7.2 21.9 27.5 22.1 26.3 18.3 15.4 17.2 16.6 35.8 17.4 30.7 14.6 13.9 21.9 14.9 13.5 24.0 13.4 1.4 15.6 10.8 24.7 1.1 1.8 9.8 11.3 22.1 4.4 14.3 13.7 13.8 28.5 7.1 13.1 5.4 4.4 6.5 18.5 4.1 18.9 5.6 4.8 1.3 8.2 1.3 5.2 16.5 0.0 3.7 23.4 23.9 0.5 13.5 29.6 11.8 10.2 3.5 9.6 4.0 17.1 4.0 26.1 1.8 2.6 9.0 15.5 9.8 15.0 6.9 4.4 11.9 5.0 14.5 9.3 10.4 12.7 29.6 16.2 6.1 20.1 10.8 14.5 2.6 40.8 11.3 1.2 6.4 10.5 12.6 0.1 23.8 8.4 1.5 20.0 1.8 1.3 1.2 1.6 15.6 1.4 1.4 0.9 10.8 1.1 24.7 3.8 0.8 9.8 13.8 14.8 14.3 23.0 13.5 17.6 18.1 16.1 14.9 14.6 GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 53.9" "Cell line enhanced" "Detected in many" "HaCaT: 10.5;HEL: 34.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "olfactory region: 888.9" "CAB004415, HPA031949, HPA058412, CAB078176" Enhanced Supported Approved Vesicles Vesicles "CAB004415: AB_627650, CAB078176: , HPA031949: , HPA058412: " "unprognostic (1.28e-1)" "prognostic favourable (7.31e-4)" "unprognostic (1.87e-2)" "prognostic favourable (8.61e-4)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (4.97e-7)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (4.27e-4)" "unprognostic (6.75e-2)" "unprognostic (9.18e-3)" "unprognostic (6.90e-5)" "unprognostic (2.93e-2)" "unprognostic (6.57e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-3)" 1.2 2.0 14.5 0.9 28.1 3.7 1.0 10.6 53.9 1.8 1.0 3.1 0.0 1.0 2.6 5.5 1.2 1.1 1.0 1.0 10.8 24.4 6.0 1.0 1.1 1.1 8.6 17.5 1.1 1.1 9.5 2.8 1.4 6.0 1.8 1.0 1.3 1.0 1.3 0.9 1.0 1.1 1.0 2.6 1.0 1.0 4.0 3.4 0.0 1.1 0.0 1.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.3 0.0 3.7 0.0 0.0 0.0 0.2 0.0 1.4 0.9 2.5 3.5 0.0 0.5 0.2 10.5 1.2 0.3 0.8 1.4 7.2 34.2 3.0 0.1 0.0 0.1 0.6 0.0 3.1 0.0 1.2 0.0 8.8 0.1 0.4 0.8 0.0 0.0 4.2 3.7 0.5 2.5 0.2 4.6 4.9 3.6 1.1 6.5 0.0 1.8 0.1 0.0 0.0 6.4 0.9 1.3 3.7 0.0 0.0 0.0 6.2 1.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 28.1 10.6 36.7 10.8 24.4 8.6 17.5 6.0 3.4 GAD2 GAD65 ENSG00000136750 "Glutamate decarboxylase 2" Q05329 10 26216307-26304558 "Enzymes, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 66.2" "Group enriched" "Detected in some" 12 "MOLT-4: 5.0;SCLC-21H: 11.4" "Group enriched" "Detected in some" 21 "glioma: 0.7;pancreatic cancer: 3.0;testis cancer: 1.2" "Region enhanced" "Detected in all" "basal ganglia: 66.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044637, CAB078177" Enhanced "CAB078177: , HPA044637: AB_10794053" "unprognostic (8.67e-2)" "unprognostic (1.11e-1)" "unprognostic (4.93e-2)" "unprognostic (2.52e-5)" "unprognostic (5.44e-2)" "unprognostic (8.08e-2)" 1.0 0.9 6.3 0.9 66.2 1.0 0.9 5.6 28.7 0.9 0.9 1.4 0.0 1.2 0.9 1.1 0.9 0.9 0.9 0.9 5.2 13.2 1.0 0.9 0.9 0.9 5.4 10.0 0.9 12.9 0.9 0.4 0.9 6.8 1.2 1.0 0.0 0.9 0.9 0.9 1.3 1.1 0.9 1.3 0.9 1.2 1.7 8.1 0.0 0.9 0.0 0.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.3 66.2 5.6 18.2 5.2 13.2 5.4 10.0 6.8 8.1 GADL1 ENSG00000144644 "Glutamate decarboxylase like 1" Q6ZQY3 3 30726200-30894765 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skeletal muscle: 21.6" "Cell line enhanced" "Detected in many" "HAP1: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039160, HPA040229" Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA039160: AB_10796222, HPA040229: AB_10796118" "unprognostic (4.96e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.60e-2)" "unprognostic (7.32e-2)" "unprognostic (5.05e-3)" "unprognostic (8.37e-2)" "unprognostic (1.23e-2)" "unprognostic (2.02e-3)" "unprognostic (1.63e-1)" "unprognostic (1.98e-5)" "unprognostic (8.81e-2)" "unprognostic (4.54e-2)" "unprognostic (4.39e-1)" "unprognostic (1.06e-1)" 0.5 0.3 0.2 0.2 0.3 1.0 0.4 0.5 0.7 0.4 0.2 0.0 0.0 0.1 0.2 1.6 1.4 0.2 2.0 2.3 0.2 0.3 0.7 0.2 1.6 0.3 0.3 0.8 0.5 0.3 0.1 0.6 0.5 2.1 0.5 0.1 0.3 0.3 0.0 21.6 0.8 0.2 2.5 0.7 0.5 0.2 1.1 0.0 0.0 1.2 3.3 0.7 0.5 0.3 1.7 0.5 1.9 0.8 0.5 1.3 0.3 1.3 0.3 0.8 1.1 0.9 0.5 1.5 0.6 0.3 0.3 0.2 1.3 1.2 1.1 0.5 0.2 0.9 9.7 0.3 0.4 1.7 0.5 1.6 1.5 0.5 0.4 0.9 3.3 0.4 0.5 0.7 0.3 0.6 1.2 4.0 0.9 1.1 0.6 1.3 1.8 0.5 1.9 2.1 1.0 1.0 1.5 1.1 0.9 1.1 0.7 2.9 1.1 0.8 5.0 1.5 1.4 1.9 0.7 1.6 0.8 0.7 0.6 0.9 1.9 1.9 0.7 0.8 1.0 0.6 0.8 1.2 0.9 0.6 0.4 1.7 1.1 1.0 1.7 0.5 0.8 0.5 1.3 0.3 0.2 0.3 0.5 0.7 0.2 0.3 0.3 0.8 2.1 0.0 GAK DNAJC26 ENSG00000178950 "Cyclin G associated kinase" O14976 4 849276-932373 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027405, HPA027459, HPA027463" Approved Supported "Golgi apparatus,Vesicles" "Golgi apparatus" Vesicles "HPA027405: AB_10611111, HPA027459: AB_10599948, HPA027463: AB_10601959" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.24e-3)" "unprognostic (1.07e-1)" "unprognostic (3.50e-3)" "unprognostic (1.68e-1)" "unprognostic (7.07e-2)" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (3.33e-3)" "prognostic favourable (1.70e-6)" "unprognostic (1.09e-3)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "prognostic favourable (7.41e-4)" 16.5 18.9 16.8 42.2 22.7 29.9 16.7 32.4 27.7 18.0 32.5 19.7 18.6 48.2 22.4 18.6 23.7 20.5 26.8 11.4 16.2 13.9 25.0 22.1 22.2 22.4 17.6 19.4 21.1 33.0 19.5 18.9 16.6 17.9 20.3 15.2 16.9 70.8 20.6 26.2 25.6 41.1 15.2 14.3 30.9 39.2 28.6 18.5 23.6 19.7 19.2 22.3 18.9 18.9 4.7 7.1 10.8 19.3 4.0 8.5 6.9 15.7 12.7 7.8 13.2 7.8 6.7 20.1 15.0 9.0 10.3 8.6 16.0 22.6 13.5 10.2 9.0 13.8 8.0 12.4 4.9 13.7 14.1 15.6 12.8 12.0 14.7 15.8 24.5 9.7 10.7 10.4 5.1 11.2 16.8 17.1 6.9 15.2 26.8 40.9 13.9 23.3 22.2 9.0 12.0 8.3 12.9 13.4 14.5 8.7 11.1 10.4 17.8 13.6 18.4 14.4 8.4 14.6 20.0 27.8 18.6 15.0 16.2 19.4 13.1 2.6 9.0 10.8 8.5 8.9 7.4 4.7 5.6 5.7 6.0 4.0 3.2 4.7 6.7 4.0 19.3 7.1 5.0 6.9 16.8 22.7 32.4 27.7 16.2 13.9 17.6 19.4 17.9 18.5 GAL3ST1 CST ENSG00000128242 "Galactose-3-O-sulfotransferase 1" Q99999 22 30554635-30574587 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 28.7;gallbladder: 13.4;intestine: 25.1;kidney: 13.3;stomach 1: 7.2" "Cell line enhanced" "Detected in some" "A549: 22.6;CACO-2: 6.2;EFO-21: 12.3;K-562: 5.2" "Cancer enriched" "Detected in many" 6 "renal cancer: 38.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001220 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA001220: AB_1078933" "unprognostic (2.69e-2)" "unprognostic (3.12e-4)" "unprognostic (5.93e-2)" "unprognostic (1.08e-2)" "unprognostic (2.32e-1)" "unprognostic (6.50e-3)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "unprognostic (2.89e-1)" "unprognostic (5.18e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" 0.8 0.6 8.4 0.7 9.6 1.2 0.8 1.4 12.3 1.4 11.3 25.8 0.0 24.2 1.3 2.3 0.8 2.2 13.4 0.5 12.1 8.3 13.3 1.6 1.5 0.9 14.0 2.6 1.2 2.9 0.6 0.5 1.3 12.4 1.2 2.8 0.3 1.0 1.9 1.9 2.1 25.1 0.7 28.7 0.7 7.2 2.5 7.8 0.0 0.6 0.0 0.4 1.0 0.7 2.3 2.8 2.3 0.7 0.3 0.8 0.0 0.1 22.6 0.4 0.2 0.0 0.0 1.7 0.0 0.1 0.0 0.0 6.2 3.1 0.3 12.3 0.0 0.2 0.0 0.0 0.0 0.2 0.8 0.3 0.2 4.1 0.5 0.1 0.3 0.2 0.0 0.1 0.1 0.0 5.2 0.6 0.0 0.1 0.3 0.8 3.2 0.3 0.2 0.1 0.6 0.9 0.1 0.3 1.5 0.0 0.4 0.2 0.1 0.1 0.6 0.2 0.1 0.2 0.0 2.0 1.2 0.3 0.1 0.1 0.2 0.9 0.7 0.1 0.4 0.5 0.7 1.8 0.7 0.8 0.2 2.3 0.5 0.8 2.3 0.3 0.3 2.8 0.1 0.0 8.4 9.6 1.4 10.3 12.1 8.3 14.0 2.6 12.4 7.8 GALC ENSG00000054983 Galactosylceramidase P54803 14 87837820-87993665 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism, Sphingolipid metabolism" "Glycosidase, Hydrolase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 35.1;HMC-1: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022196 Approved "Intracellular and membrane" 16000 "CAB022196: " "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (9.39e-2)" "unprognostic (3.08e-1)" "unprognostic (9.70e-2)" "unprognostic (1.73e-1)" "unprognostic (6.56e-2)" "unprognostic (8.44e-3)" "unprognostic (8.08e-2)" "unprognostic (1.84e-2)" "unprognostic (6.00e-2)" "unprognostic (2.13e-1)" "unprognostic (6.80e-2)" "unprognostic (2.72e-2)" 13.8 17.7 21.2 13.2 32.2 18.9 15.4 16.3 25.5 12.3 15.8 28.8 9.6 30.3 10.7 12.1 6.5 20.1 17.4 19.6 22.0 19.5 20.5 11.1 23.0 18.0 30.7 20.1 17.3 13.6 14.4 12.6 15.6 24.9 14.1 16.9 13.3 8.9 10.1 9.3 9.4 30.2 9.3 33.8 14.3 14.9 21.6 26.1 8.6 23.5 5.8 7.3 12.6 11.4 1.7 5.7 20.8 10.5 9.4 16.3 6.4 0.0 8.2 3.0 0.0 10.2 9.2 0.0 3.7 7.6 3.6 4.3 4.5 35.1 2.1 11.4 3.6 0.5 0.0 0.4 4.4 1.1 0.2 12.1 0.3 0.0 8.4 0.0 33.2 9.0 2.8 2.4 0.0 9.6 4.0 1.6 6.0 0.8 0.0 1.8 2.7 0.9 0.0 0.2 0.1 5.7 3.3 2.8 6.7 10.3 1.7 0.0 8.5 8.3 8.1 0.0 5.6 2.3 0.0 1.7 3.2 0.0 1.0 2.8 8.0 12.8 9.5 20.8 7.5 10.5 16.3 1.7 5.7 7.2 5.7 0.8 4.2 4.9 7.8 9.4 8.0 1.0 3.2 6.4 21.2 32.2 16.3 25.5 22.0 19.5 30.7 20.1 24.9 26.1 GALE SDR1E1 ENSG00000117308 UDP-galactose-4-epimerase Q14376 1 23795599-23800804 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" Isomerase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007340 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "HPA007340: AB_1078934" "unprognostic (1.65e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (1.41e-2)" "unprognostic (3.03e-3)" "unprognostic (1.17e-2)" "unprognostic (3.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.59e-1)" "unprognostic (2.65e-1)" "unprognostic (1.56e-2)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (7.51e-2)" "unprognostic (2.12e-1)" "prognostic favourable (2.68e-4)" "unprognostic (1.41e-2)" 4.4 5.5 4.8 5.6 6.1 1.8 5.0 4.3 8.7 9.1 22.3 3.2 12.4 20.0 3.0 6.0 26.2 6.4 34.7 3.7 4.0 4.1 18.2 26.1 7.7 3.9 3.7 5.2 2.4 15.9 7.7 3.5 29.4 3.5 4.8 23.8 5.5 32.1 6.9 1.7 3.9 30.4 4.1 3.6 8.6 46.7 3.4 2.6 3.7 2.3 9.8 19.6 8.1 8.4 3.1 10.6 2.0 18.6 19.4 5.2 4.7 16.2 19.5 7.8 12.4 2.9 4.1 7.6 11.1 15.0 19.7 14.7 17.8 54.5 3.8 15.6 6.5 18.0 6.9 28.4 15.0 8.2 4.5 10.9 9.9 19.3 29.8 4.7 3.2 8.8 15.0 18.1 45.5 16.9 12.1 1.0 14.0 17.3 7.7 5.0 2.2 19.0 9.2 7.6 4.9 31.9 10.9 3.0 6.9 20.1 18.3 19.7 13.4 3.9 9.2 14.4 21.4 14.8 13.6 5.0 12.1 5.0 15.2 20.0 7.7 1.1 7.7 1.7 5.1 15.5 5.2 3.1 3.1 4.1 10.6 1.0 3.6 2.5 2.0 19.4 18.6 3.0 5.1 4.7 4.8 6.1 4.3 8.7 4.0 4.1 3.7 5.2 3.5 2.6 GALK1 GALK ENSG00000108479 "Galactokinase 1" P51570 17 75751594-75765711 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Kinase, Transferase" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 36.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007094, HPA016960" Approved Approved "Golgi apparatus,Cytosol" 8600 Cytosol "Golgi apparatus" "HPA007094: AB_1078939, HPA016960: AB_1849430" "unprognostic (1.16e-1)" "unprognostic (1.33e-2)" "unprognostic (1.81e-2)" "unprognostic (2.94e-2)" "unprognostic (1.00e-1)" "unprognostic (2.21e-1)" "unprognostic (1.29e-1)" "unprognostic (7.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.04e-2)" "unprognostic (1.06e-1)" "unprognostic (2.35e-2)" "prognostic unfavourable (1.55e-6)" "unprognostic (3.04e-1)" "unprognostic (1.71e-1)" "unprognostic (2.77e-1)" "prognostic unfavourable (1.62e-5)" 6.4 3.3 3.8 6.2 4.4 3.6 14.2 4.6 5.1 4.7 9.3 3.7 3.5 15.9 4.7 5.0 9.0 4.8 3.8 7.2 3.6 3.6 12.3 31.6 4.7 11.7 4.3 3.8 5.2 16.0 1.9 2.6 4.6 3.2 4.7 1.3 3.6 14.9 4.7 5.4 6.2 17.3 3.7 4.0 7.2 5.3 5.7 3.3 7.6 3.3 5.1 4.8 3.6 5.0 10.6 36.7 20.7 30.2 5.7 9.4 14.6 8.0 30.3 1.8 8.5 2.7 6.8 7.1 6.5 5.4 6.7 6.3 16.8 1.6 12.5 8.2 3.4 4.7 2.0 1.9 0.7 5.4 19.0 7.8 11.5 28.1 9.2 5.2 17.3 6.0 2.6 3.3 1.4 15.6 6.2 7.7 4.1 34.4 14.4 19.7 2.1 15.7 17.3 21.1 20.8 3.7 3.3 4.1 11.4 5.6 14.4 14.2 11.7 8.6 13.7 10.0 9.6 9.5 5.7 19.5 4.8 3.2 11.2 12.2 7.7 2.6 30.2 8.3 9.4 25.5 8.5 10.6 7.8 8.6 27.2 6.8 4.2 6.2 20.7 5.7 20.2 36.7 8.7 14.6 3.8 4.4 4.6 5.1 3.6 3.6 4.3 3.8 3.2 3.3 GALK2 GK2 ENSG00000156958 "Galactokinase 2" Q01415 15 49155656-49367869 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043564, HPA048267" Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA043564: AB_2678557, HPA048267: " "unprognostic (2.27e-2)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "prognostic favourable (7.31e-4)" "unprognostic (3.04e-1)" "unprognostic (9.78e-2)" "unprognostic (2.66e-1)" "unprognostic (1.95e-1)" "unprognostic (2.30e-1)" "unprognostic (8.67e-3)" "unprognostic (2.25e-2)" "unprognostic (2.43e-1)" "prognostic favourable (1.88e-5)" "unprognostic (2.33e-1)" "unprognostic (9.79e-2)" "unprognostic (2.13e-2)" "unprognostic (1.93e-1)" 12.7 24.9 10.2 9.2 15.3 6.5 12.4 15.7 15.3 14.7 16.3 15.3 25.6 21.5 16.0 9.9 11.5 13.5 9.9 14.2 11.3 10.3 32.3 28.4 12.7 8.0 16.2 9.4 11.5 18.5 19.4 34.2 10.8 15.3 11.1 17.9 13.2 12.2 16.3 12.5 11.6 17.9 11.8 13.9 12.8 13.9 9.2 14.8 14.6 16.7 10.9 11.5 10.3 11.6 9.6 10.4 24.2 11.3 12.8 23.1 8.7 6.2 7.3 3.4 4.5 8.7 13.6 9.9 6.5 8.7 6.5 7.7 9.3 6.6 2.0 5.2 6.8 9.1 13.4 9.3 9.2 11.2 3.9 11.7 7.0 7.8 9.5 8.0 3.7 7.0 17.1 6.9 17.3 13.1 11.6 11.4 7.0 6.7 5.8 6.4 1.4 7.0 7.1 4.1 30.3 12.0 5.9 4.1 2.7 7.2 15.0 12.3 7.4 7.8 7.2 6.4 4.4 25.9 6.1 9.4 32.3 3.8 9.9 30.7 8.7 24.2 10.6 18.6 12.8 11.3 13.6 9.6 13.1 12.6 10.4 6.7 10.5 10.7 5.4 12.8 10.8 9.2 23.1 8.7 10.2 15.3 15.7 15.3 11.3 10.3 16.2 9.4 15.3 14.8 GALM ENSG00000143891 "Galactose mutarotase" Q96C23 2 38665910-38741237 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 54.2" "Cell line enhanced" "Detected in many" "Karpas-707: 27.9;U-266/70: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 29.7" "Group enriched" "Detected in all" 5 "granulocytes: 13.2;T-cells: 29.7" "Low region specificity" "Detected in all" "HPA035472, HPA035473, HPA064835" Enhanced Approved Nucleoplasm 570000 Nucleoplasm "HPA035472: AB_10669906, HPA035473: AB_2674642, HPA064835: AB_2732723" "unprognostic (5.02e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (9.20e-2)" "unprognostic (1.88e-2)" "unprognostic (9.99e-3)" "unprognostic (1.63e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (6.65e-2)" "unprognostic (6.45e-2)" "prognostic favourable (9.06e-5)" "unprognostic (1.70e-2)" "unprognostic (1.62e-1)" "unprognostic (4.34e-1)" "prognostic favourable (1.32e-4)" 11.2 54.2 3.1 10.4 2.5 0.7 4.6 1.9 2.7 5.9 28.4 2.5 44.3 22.7 6.8 11.8 3.4 11.6 13.3 7.7 2.5 1.8 39.1 28.8 5.8 6.4 2.4 1.9 6.4 7.9 10.4 2.4 3.1 2.9 8.1 10.7 15.3 7.9 29.1 4.6 2.2 39.8 5.4 3.3 4.1 5.0 4.7 2.1 6.4 7.4 3.3 9.3 6.5 5.2 2.8 4.5 13.2 2.1 2.3 29.7 5.3 0.0 10.7 3.3 0.0 11.1 6.5 5.9 1.3 4.0 3.0 4.9 11.9 5.6 4.1 7.9 5.9 1.7 4.6 0.3 6.0 18.8 7.8 2.2 2.9 23.8 4.0 0.9 0.1 4.5 0.1 6.8 0.0 3.4 6.3 27.9 5.5 0.3 9.1 14.8 5.0 3.5 5.7 0.2 8.1 3.9 18.4 0.6 4.7 0.0 7.6 5.4 3.7 2.1 1.3 1.0 0.2 7.4 0.4 31.3 21.2 0.1 6.9 2.6 0.1 13.2 2.1 1.8 10.2 1.5 15.0 2.8 16.0 14.8 4.5 2.5 5.8 5.0 5.1 2.3 0.2 0.4 29.7 5.3 3.1 2.5 1.9 2.7 2.5 1.8 2.4 1.9 2.9 2.1 GALNS "GALNAC6S, GAS" ENSG00000141012 "Galactosamine (N-acetyl)-6-sulfatase" P34059 16 88813734-88856970 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Dwarfism, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 7.1;granulocytes: 19.3;monocytes: 11.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026404, HPA042433" Supported Approved Cytosol "Intracellular and membrane" 2400000 Cytosol "CAB026404: , HPA042433: " "unprognostic (3.16e-1)" "unprognostic (9.98e-2)" "unprognostic (4.03e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (8.08e-3)" "prognostic unfavourable (3.66e-4)" "unprognostic (4.15e-3)" "unprognostic (1.32e-1)" "unprognostic (4.84e-3)" "unprognostic (2.00e-1)" "unprognostic (3.53e-2)" "unprognostic (4.12e-3)" "unprognostic (4.24e-2)" "unprognostic (5.54e-2)" "unprognostic (3.59e-2)" "unprognostic (6.84e-2)" 11.9 14.9 9.3 11.2 11.1 25.0 14.8 12.9 15.4 11.1 15.5 11.5 8.8 13.3 9.0 19.9 10.2 14.8 12.7 12.5 11.2 13.9 13.7 17.8 14.7 10.6 11.8 5.2 11.9 7.3 9.9 13.2 15.6 11.6 10.5 8.3 7.1 10.6 9.0 7.1 10.0 17.2 9.4 9.4 10.4 9.5 27.4 8.8 7.9 14.5 6.1 9.0 11.1 13.0 2.1 7.1 19.3 11.2 2.4 3.1 4.7 2.5 19.3 2.8 19.8 22.3 10.7 19.4 8.1 12.6 8.9 6.9 10.1 16.7 3.2 17.2 13.2 14.9 4.1 6.4 5.4 2.1 6.4 2.0 7.9 5.7 15.0 1.5 13.1 14.9 12.5 9.9 2.8 7.6 4.3 1.9 5.2 14.8 4.0 6.4 6.5 9.0 8.6 2.5 5.3 5.5 5.9 7.3 5.6 19.2 1.8 9.6 12.5 14.2 14.1 19.5 14.9 19.9 4.4 2.0 1.9 5.4 21.1 13.1 11.5 0.9 11.2 19.3 3.1 8.0 2.6 2.1 1.8 2.7 7.1 0.9 1.7 2.1 14.2 2.4 5.6 3.0 3.0 4.7 9.3 11.1 12.9 15.4 11.2 13.9 11.8 5.2 11.6 8.8 GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" 1600000 "HPA012628: AB_1849439" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" "unprognostic (2.08e-1)" "unprognostic (2.83e-2)" "unprognostic (1.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" "unprognostic (3.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (4.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.07e-2)" "unprognostic (8.60e-2)" 15.0 14.2 11.3 11.4 16.0 9.7 24.2 14.3 12.3 15.1 18.7 11.3 8.3 18.9 10.3 13.7 31.8 8.9 13.0 18.4 15.3 9.7 12.9 21.8 12.0 27.4 14.9 13.3 10.5 22.2 4.6 15.0 22.9 12.5 11.7 18.7 15.7 28.3 8.4 19.9 27.6 24.7 15.8 13.7 17.9 11.9 9.8 12.6 13.8 13.5 16.0 17.3 32.3 19.3 6.2 6.7 11.1 9.1 6.6 5.8 2.0 7.7 8.5 10.1 9.3 20.2 19.2 13.4 8.2 8.8 7.6 7.0 5.1 15.3 9.2 8.8 8.8 6.0 5.0 15.7 12.2 10.8 4.6 11.7 16.7 11.7 10.1 25.4 15.7 13.0 15.0 11.9 13.2 82.2 3.5 12.3 29.6 6.2 7.4 9.7 10.4 4.1 9.3 13.3 4.4 31.4 36.4 5.5 10.8 14.6 10.7 8.6 8.2 20.0 28.5 14.1 5.7 9.2 9.0 17.7 8.4 17.7 9.9 17.4 7.3 8.4 5.4 11.1 5.1 6.7 5.8 6.2 3.6 4.7 6.1 3.8 3.4 4.9 6.4 6.6 9.1 6.7 3.6 2.0 11.3 16.0 14.3 12.3 15.3 9.7 14.9 13.3 12.5 12.6 GALNT10 GalNAc-T10 ENSG00000164574 "Polypeptide N-acetylgalactosaminyltransferase 10" Q86SR1 5 154190730-154420984 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 43.7" "Cell line enhanced" "Detected in many" "TIME: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007525 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" 830000 "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA007525: AB_1849443" "unprognostic (6.99e-2)" "unprognostic (4.33e-2)" "unprognostic (9.85e-2)" "prognostic favourable (3.33e-6)" "unprognostic (1.63e-1)" "unprognostic (6.98e-2)" "unprognostic (6.95e-3)" "unprognostic (2.38e-1)" "unprognostic (3.34e-1)" "prognostic unfavourable (5.69e-4)" "unprognostic (2.88e-3)" "unprognostic (2.63e-1)" "unprognostic (1.54e-1)" "unprognostic (7.76e-3)" "unprognostic (1.22e-1)" "unprognostic (1.61e-2)" "unprognostic (3.08e-1)" 9.5 13.5 8.4 15.4 9.1 10.1 8.7 3.2 6.2 15.9 10.6 14.4 1.0 8.8 4.9 11.5 5.9 9.2 17.8 7.7 6.9 7.5 6.8 3.4 10.1 11.5 7.2 5.2 43.7 9.2 14.1 9.7 5.2 10.1 8.3 9.4 31.6 11.6 2.4 5.6 4.0 12.4 14.1 7.7 16.7 13.8 4.3 9.2 5.6 10.6 4.2 9.3 7.5 10.0 4.7 3.1 5.7 3.8 3.9 7.5 2.1 7.4 25.4 6.2 5.4 13.2 11.8 4.8 21.5 12.0 8.6 8.2 3.5 17.1 4.8 15.2 36.1 1.3 2.8 16.8 7.9 12.6 2.0 13.3 4.8 4.8 10.2 2.8 13.0 14.6 3.9 6.9 10.3 16.4 3.0 15.4 14.6 7.7 0.3 2.0 2.4 5.2 1.5 3.3 4.8 11.9 5.1 0.8 2.0 9.5 35.6 2.8 13.8 2.2 48.2 20.9 5.0 5.1 22.8 4.4 4.3 2.6 13.7 5.7 6.3 3.4 2.7 5.3 7.5 3.6 6.6 4.5 4.3 4.8 3.1 4.7 1.9 5.3 5.7 3.9 3.8 2.7 3.5 2.1 8.4 9.1 3.2 6.2 6.9 7.5 7.2 5.2 10.1 9.2 GALNT11 GalNAc-T11 ENSG00000178234 "Polypeptide N-acetylgalactosaminyltransferase 11" Q8NCW6 7 152025674-152122347 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Notch signaling pathway" "Glycosyltransferase, Transferase" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 82.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039330 Uncertain "HPA039330: AB_10795249" "unprognostic (6.09e-2)" "unprognostic (1.22e-1)" "unprognostic (4.98e-2)" "unprognostic (3.48e-2)" "prognostic unfavourable (9.54e-4)" "unprognostic (1.76e-1)" "unprognostic (9.10e-3)" "unprognostic (1.56e-3)" "unprognostic (1.38e-1)" "unprognostic (3.65e-1)" "unprognostic (3.82e-2)" "unprognostic (1.64e-1)" "prognostic favourable (2.24e-6)" "unprognostic (1.33e-1)" "unprognostic (1.17e-1)" "unprognostic (2.97e-1)" "unprognostic (9.51e-2)" 10.7 9.4 11.1 5.1 18.7 3.8 10.4 20.8 21.8 9.1 7.5 11.4 7.1 5.1 9.6 9.2 9.8 8.3 9.3 9.2 11.4 9.3 82.0 7.1 9.6 4.9 7.0 13.4 10.6 29.7 19.3 10.5 15.9 34.1 12.0 6.5 21.7 7.8 9.8 8.8 8.3 6.9 9.5 6.5 8.5 7.6 7.3 4.4 4.6 12.5 5.6 6.4 9.4 8.1 6.3 8.3 8.2 12.5 15.7 19.3 8.7 10.5 9.4 14.0 15.6 32.5 32.1 14.4 8.4 9.6 7.1 6.7 7.6 11.1 0.0 22.0 13.6 5.0 6.6 11.9 8.8 8.7 9.8 2.1 8.6 6.7 10.7 9.4 11.2 28.2 15.4 5.9 5.0 12.8 10.6 0.1 17.7 9.1 8.1 8.6 11.5 7.6 0.0 6.1 0.3 23.4 16.3 12.5 16.6 14.0 6.8 11.3 10.1 8.2 11.5 9.6 3.4 12.0 9.2 3.1 4.0 0.1 19.9 9.2 32.6 5.8 8.3 8.2 19.3 9.4 19.0 6.3 10.7 17.7 8.3 3.8 9.2 14.0 4.4 15.7 12.5 2.5 7.9 8.7 11.1 18.7 20.8 21.8 11.4 9.3 7.0 13.4 34.1 4.4 GALNT12 GalNAc-T12 ENSG00000119514 "Polypeptide N-acetylgalactosaminyltransferase 12" Q8IXK2 9 98807699-98850081 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 34.7" "Cell line enriched" "Detected in many" 4 "U-2197: 58.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 17.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA048292 Enhanced "Intracellular and membrane" 15000 "HPA048292: " "unprognostic (7.85e-3)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.97e-3)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.61e-2)" "unprognostic (7.71e-2)" "prognostic favourable (3.24e-4)" "unprognostic (9.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-3)" "unprognostic (6.87e-2)" 7.5 1.7 1.0 9.5 2.3 0.6 3.7 17.7 1.6 4.0 29.6 1.7 7.4 14.6 1.8 34.7 15.2 3.2 20.5 1.1 1.4 1.6 2.9 0.4 13.8 1.1 3.3 1.0 1.0 9.2 4.0 3.1 1.0 2.7 4.2 24.8 4.0 15.2 6.6 1.1 2.6 22.4 15.4 1.3 1.5 23.5 3.4 1.1 2.8 9.3 8.1 23.9 9.0 3.4 0.8 0.4 1.6 0.0 2.2 2.5 0.4 1.8 1.4 1.2 4.8 3.7 2.9 0.0 0.5 0.7 0.7 1.7 0.3 7.7 0.0 1.8 0.3 13.5 1.0 0.4 0.6 9.1 0.6 0.8 0.1 0.0 0.1 0.5 0.2 1.4 0.3 2.3 0.0 0.8 10.3 0.0 0.2 4.8 0.9 1.6 6.0 2.0 2.2 0.1 0.0 0.8 2.7 4.5 0.4 0.2 11.0 1.0 1.6 1.6 1.5 0.0 0.1 58.4 0.0 0.7 1.6 0.8 13.6 0.0 0.3 0.0 0.0 1.6 1.4 0.0 2.5 0.1 1.9 0.8 0.2 0.8 2.3 1.5 0.1 2.2 0.0 0.4 0.1 0.4 1.0 2.3 17.7 1.6 1.4 1.6 3.3 1.0 2.7 1.1 GALNT13 "GalNAc-T13, KIAA1918" ENSG00000144278 "Polypeptide N-acetylgalactosaminyltransferase 13" Q8IUC8 2 153871913-154453849 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.0" "Cell line enhanced" "Detected in some" "SH-SY5Y: 27.7;U-251 MG: 7.2;WM-115: 20.7" "Cancer enriched" "Detected in some" 5 "glioma: 4.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "eosinophil: 2.2" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060775 Approved "HPA060775: " "unprognostic (1.97e-1)" "unprognostic (3.43e-3)" "unprognostic (2.47e-2)" "unprognostic (1.00e-3)" "unprognostic (4.21e-3)" "unprognostic (7.73e-3)" "unprognostic (6.50e-2)" "unprognostic (8.17e-2)" "unprognostic (3.57e-1)" "unprognostic (9.15e-2)" "unprognostic (3.83e-2)" "unprognostic (3.09e-2)" "unprognostic (5.17e-2)" "unprognostic (2.05e-5)" "unprognostic (8.61e-3)" "unprognostic (1.52e-1)" "unprognostic (2.05e-1)" 3.0 7.7 8.5 0.7 6.2 0.6 1.4 39.0 29.1 3.1 0.9 7.9 0.6 0.7 3.1 2.3 0.7 1.0 1.1 0.6 7.8 8.9 0.6 0.4 3.4 0.4 8.3 3.1 1.1 1.0 0.5 3.1 1.0 10.5 3.6 1.0 1.1 10.9 2.6 1.7 0.8 0.8 2.0 10.4 0.5 1.1 1.3 4.3 0.0 0.4 0.0 0.5 1.5 0.2 0.2 0.6 2.2 0.9 0.2 0.8 0.0 0.0 3.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.7 0.0 3.2 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.1 4.6 4.3 0.0 0.2 0.6 0.0 0.0 4.7 27.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.2 0.3 0.0 0.0 4.5 0.0 20.7 0.0 0.9 2.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 0.1 0.2 0.0 0.6 0.4 0.0 8.5 6.2 39.0 7.4 7.8 8.9 8.3 3.1 10.5 4.3 GALNT14 "FLJ12691, GalNac-T10, GalNac-T14" ENSG00000158089 "Polypeptide N-acetylgalactosaminyltransferase 14" Q96FL9 2 30910467-31155202 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 42.7" "Cell line enhanced" "Detected in many" "A549: 12.9;RPMI-8226: 14.9;RPTEC TERT1: 22.0;RT4: 16.3" "Cancer enriched" "Detected in many" 7 "renal cancer: 45.9" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 7 "neutrophil: 10.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 10.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA030138 Approved "Nucleoplasm,Golgi apparatus" 9400 "Golgi apparatus" Nucleoplasm "HPA030138: " "unprognostic (5.69e-2)" "unprognostic (1.35e-1)" "unprognostic (2.05e-2)" "unprognostic (2.82e-3)" "unprognostic (3.85e-2)" "unprognostic (2.10e-2)" "unprognostic (3.32e-1)" "unprognostic (7.58e-2)" "unprognostic (1.96e-1)" "unprognostic (2.80e-1)" "unprognostic (1.22e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (5.18e-3)" "unprognostic (2.67e-2)" "unprognostic (2.56e-1)" "unprognostic (9.51e-3)" 1.2 1.5 1.5 0.9 3.7 4.3 1.1 1.8 9.6 1.4 0.6 1.8 0.3 0.6 0.6 1.0 10.2 1.1 3.7 0.4 1.6 1.5 42.7 1.2 0.6 2.6 1.2 2.3 0.9 2.7 7.6 5.7 0.2 0.9 1.7 0.2 2.1 1.7 0.2 0.4 1.9 3.1 0.7 0.8 1.8 0.6 1.6 0.3 0.1 1.1 1.0 4.2 2.0 1.4 1.4 0.0 10.6 0.0 0.0 0.0 0.1 10.9 12.9 0.0 0.0 0.0 0.0 0.0 3.6 1.9 2.4 0.3 0.0 0.0 10.2 3.7 0.2 0.0 0.4 0.5 0.4 0.3 1.3 5.7 0.0 0.0 0.0 8.2 0.0 0.0 2.3 0.0 8.5 0.0 0.0 9.1 0.0 5.0 0.0 0.0 6.1 0.0 7.1 0.0 14.9 22.0 16.3 12.1 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.2 0.9 2.8 0.0 0.0 5.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.1 1.5 3.7 1.8 9.6 1.6 1.5 1.2 2.3 0.9 0.3 GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174649-16231992 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 66.7;brain: 52.3" "Group enriched" "Detected in some" 5 "ASC diff: 43.8;ASC TERT1: 43.2;HSkMC: 32.9" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cerebellum: 10.7;pons and medulla: 6.7" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" 25000 "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" 66.7 5.3 7.6 2.6 17.4 1.1 22.8 2.3 31.5 3.9 8.6 28.1 1.1 2.8 3.5 3.3 11.4 5.3 5.2 7.3 14.8 6.6 8.3 2.8 3.1 3.4 38.9 8.4 8.4 3.2 1.6 1.0 35.5 24.8 4.9 3.8 1.3 8.0 4.1 17.3 11.6 5.3 10.5 52.3 12.8 4.6 8.1 19.9 0.0 6.3 1.6 1.5 16.6 23.5 0.6 0.9 0.9 0.3 0.3 0.4 0.3 0.0 0.0 0.0 0.0 43.8 43.2 0.0 0.9 0.7 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 32.9 0.0 0.4 0.5 0.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 7.7 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.2 0.3 0.2 0.2 0.1 0.4 0.2 0.3 0.0 0.6 0.4 0.2 0.9 0.3 0.3 0.9 0.3 0.3 7.6 17.4 2.3 13.6 14.8 6.6 38.9 8.4 24.8 19.9 GALNT16 "GalNAc-T16, GALNTL1, KIAA1130" ENSG00000100626 "Polypeptide N-acetylgalactosaminyltransferase 16" Q8N428 14 69259277-69357033 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 7.7;ASC diff: 10.2;hTEC/SVTERT24-B: 14.4;SCLC-21H: 7.6;U-2 OS: 17.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059136 Approved Approved Nucleoplasm 250000 Nucleoplasm "HPA059136: " "unprognostic (9.71e-3)" "unprognostic (7.47e-2)" "unprognostic (4.02e-1)" "unprognostic (2.30e-2)" "unprognostic (6.71e-2)" "unprognostic (5.72e-3)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-4)" "unprognostic (1.31e-2)" "prognostic favourable (5.23e-6)" "unprognostic (5.38e-3)" "unprognostic (3.34e-2)" "unprognostic (3.93e-2)" "unprognostic (7.96e-5)" 13.6 15.5 20.0 2.9 17.9 0.8 14.5 16.1 21.7 7.8 4.1 5.0 4.0 3.2 6.4 6.0 5.1 6.5 4.8 27.6 18.3 27.2 5.6 3.0 4.2 4.2 6.6 25.2 2.8 5.6 4.0 4.1 1.2 13.0 4.6 3.4 1.7 28.9 6.6 5.3 7.0 5.0 11.3 8.7 14.3 2.4 3.3 3.3 0.0 3.5 6.3 2.2 5.0 3.8 0.5 0.2 1.3 0.5 0.3 0.3 0.2 0.0 0.7 7.7 0.2 10.2 4.6 0.0 1.1 0.0 1.4 1.9 0.4 0.0 0.0 0.2 1.2 0.0 2.5 0.0 0.2 0.1 5.3 0.0 0.1 0.3 0.1 0.0 0.5 0.5 0.0 14.4 0.0 0.8 0.0 0.0 2.4 0.4 0.0 0.0 1.4 0.1 0.0 4.0 0.0 0.5 0.0 7.6 2.5 1.7 0.3 0.0 0.2 0.0 0.1 1.6 17.3 2.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.5 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.0 0.5 0.3 0.2 1.3 0.3 0.1 0.2 0.1 0.2 20.0 17.9 16.1 16.2 18.3 27.2 6.6 25.2 13.0 3.3 GALNT17 "GalNAc-T17, GalNAc-T19, GalNAc-T5L, GALNTL3, ppGalNAc-T17, WBSCR17" ENSG00000185274 "Polypeptide N-acetylgalactosaminyltransferase 17" Q6IS24 7 71132169-71713600 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.9" "Cell line enhanced" "Detected in some" "AF22: 9.5;NTERA-2: 7.2;RPMI-8226: 7.9;SK-BR-3: 30.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA013624, HPA047986" Approved Uncertain "Nucleoplasm,Nucleoli,Nuclear bodies,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "Nucleoli, Nuclear bodies" "HPA013624: AB_1858787, HPA047986: " "unprognostic (2.79e-2)" "unprognostic (6.83e-2)" "unprognostic (5.54e-2)" "unprognostic (3.66e-3)" "unprognostic (1.50e-1)" "unprognostic (2.62e-1)" "unprognostic (6.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.00e-1)" "prognostic favourable (4.60e-4)" "unprognostic (2.00e-1)" "unprognostic (4.73e-1)" "unprognostic (1.96e-2)" "unprognostic (9.63e-3)" "prognostic favourable (3.91e-4)" "unprognostic (1.92e-1)" "unprognostic (7.94e-3)" 1.8 7.8 8.2 2.1 13.9 0.5 1.2 25.7 42.9 2.3 4.9 1.7 1.9 0.8 7.9 4.6 8.9 4.4 2.7 19.4 13.2 4.6 2.3 0.6 3.5 0.5 2.1 12.0 22.3 9.4 0.6 4.1 0.7 4.5 9.1 1.4 1.2 1.7 8.3 1.9 0.8 1.5 12.3 1.2 3.3 1.1 3.8 0.8 0.3 9.4 0.0 1.8 10.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 7.9 0.0 0.0 0.5 0.0 0.0 30.4 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 13.9 25.7 22.5 13.2 4.6 2.1 12.0 4.5 0.8 GALNT18 "GalNAc-T18, GALNT15, GALNTL4, MGC71806" ENSG00000110328 "Polypeptide N-acetylgalactosaminyltransferase 18" Q6P9A2 11 11270876-11622005 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 18.5;HaCaT: 23.8;HBEC3-KT: 16.6;PC-3: 16.7;RPMI-8226: 17.4;SK-BR-3: 21.7;U-87 MG: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 17 "gdT-cell: 1.7" "Lineage enriched" "Detected in single" 17 "T-cells: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012955 Approved Approved Mitochondria 200000 Mitochondria "HPA012955: AB_1849460" "unprognostic (1.26e-1)" "unprognostic (2.80e-1)" "unprognostic (3.69e-2)" "prognostic unfavourable (1.29e-4)" "unprognostic (7.37e-2)" "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (6.68e-2)" "unprognostic (6.04e-2)" "unprognostic (2.05e-1)" "unprognostic (5.24e-2)" "unprognostic (1.70e-1)" "unprognostic (2.66e-3)" "unprognostic (3.54e-2)" "unprognostic (1.63e-1)" "unprognostic (2.10e-1)" "unprognostic (1.81e-2)" 18.6 6.0 15.5 4.9 13.5 0.8 9.1 21.3 16.2 7.0 13.3 5.8 8.3 3.9 15.0 6.4 7.8 7.6 12.6 21.9 13.1 7.0 19.7 6.6 31.2 5.8 10.0 12.1 3.8 9.5 9.1 4.3 26.6 12.8 8.2 4.3 7.1 10.4 11.5 6.1 7.6 4.9 15.0 6.5 4.0 4.1 13.3 8.4 0.7 39.2 5.6 4.2 10.3 9.1 0.0 0.0 0.0 0.0 0.0 1.7 0.3 18.5 6.8 0.9 4.2 0.0 0.0 0.1 2.0 5.1 0.2 0.0 0.7 2.4 0.0 1.4 0.0 23.8 4.5 16.6 0.0 0.0 6.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 6.9 0.0 6.3 0.0 0.0 0.0 0.9 4.5 0.2 0.0 0.7 16.7 0.0 0.0 17.4 12.8 2.3 0.3 1.9 3.4 21.7 0.1 4.5 0.0 0.0 0.3 3.8 0.1 0.1 0.0 0.0 0.0 15.8 0.0 4.6 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 15.5 13.5 21.3 16.2 13.1 7.0 10.0 12.1 12.8 8.4 GALNT2 GalNAc-T2 ENSG00000143641 "Polypeptide N-acetylgalactosaminyltransferase 2" Q10471 1 230057990-230282124 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 140.3" "Cell line enhanced" "Detected in all" "WM-115: 89.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011222 Supported Supported "Golgi apparatus" "Intracellular and membrane" 11000000 "Golgi apparatus" "HPA011222: AB_1849446" "unprognostic (1.26e-1)" "prognostic unfavourable (1.22e-6)" "unprognostic (1.15e-2)" "unprognostic (1.35e-2)" "unprognostic (8.70e-3)" "unprognostic (7.77e-3)" "unprognostic (1.25e-1)" "prognostic unfavourable (8.48e-8)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (1.70e-2)" "unprognostic (9.65e-2)" "prognostic unfavourable (2.79e-13)" "unprognostic (3.79e-3)" "unprognostic (1.49e-1)" "unprognostic (3.64e-2)" "unprognostic (1.89e-1)" 19.5 25.6 11.1 19.6 10.1 6.9 20.4 7.7 12.5 11.7 12.7 9.1 10.5 11.3 13.7 11.5 11.5 13.2 17.0 13.9 12.5 8.5 17.5 140.3 13.2 20.4 8.4 9.0 24.8 35.9 4.3 7.3 16.6 12.6 10.8 7.5 10.5 11.1 9.6 42.2 8.4 11.3 14.6 13.6 9.5 18.0 12.7 8.2 28.4 10.7 10.7 7.0 14.9 13.1 6.7 13.5 3.5 10.1 2.7 5.3 6.3 15.9 21.3 12.6 14.9 24.2 20.7 26.0 30.3 18.8 12.3 11.8 9.2 30.4 4.0 22.5 15.9 31.2 8.3 25.4 10.4 40.3 10.8 12.3 47.7 10.2 13.2 4.7 24.2 29.6 12.6 16.4 6.6 14.4 15.3 6.2 13.6 4.4 24.3 4.7 17.2 20.4 27.1 18.0 12.4 12.1 19.0 4.0 14.9 30.7 1.6 18.4 9.7 8.8 34.1 12.1 23.3 27.2 24.0 20.7 11.9 9.0 31.2 9.4 89.5 1.1 10.1 3.5 4.7 9.6 3.6 3.8 2.9 4.7 7.9 6.7 2.8 5.3 3.2 2.7 9.6 13.5 3.4 6.3 11.1 10.1 7.7 11.8 12.5 8.5 8.4 9.0 12.6 8.2 GALNT3 "GalNAc-T3, HFTC, HHS" ENSG00000115339 "Polypeptide N-acetylgalactosaminyltransferase 3" Q14435 2 165747591-165794682 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 32.5;HaCaT: 37.5;HBEC3-KT: 25.3;hTCEpi: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA007613 Enhanced Supported "Golgi apparatus" 88000 "Golgi apparatus" "HPA007613: AB_1078941" "unprognostic (1.95e-1)" "prognostic unfavourable (2.08e-4)" "unprognostic (1.16e-3)" "unprognostic (2.78e-1)" "unprognostic (3.22e-2)" "prognostic unfavourable (4.10e-4)" "unprognostic (4.13e-2)" "unprognostic (4.47e-2)" "unprognostic (2.74e-1)" "unprognostic (6.44e-2)" "unprognostic (3.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.79e-2)" "unprognostic (3.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-1)" 1.5 1.7 1.5 6.3 1.7 14.6 12.0 2.2 1.7 11.9 21.3 3.6 6.5 15.5 2.4 8.8 23.4 15.7 26.4 0.9 1.9 2.1 15.1 2.1 15.3 0.6 4.2 1.2 6.4 31.2 3.0 23.0 7.0 4.2 13.8 21.2 1.7 35.7 5.4 0.7 6.7 37.4 0.5 4.8 23.3 28.9 17.6 3.3 1.5 37.6 15.1 20.8 11.7 9.3 3.3 7.5 21.1 5.7 5.8 5.3 2.3 20.1 0.0 0.1 0.0 0.0 0.8 13.4 4.4 1.7 1.7 4.5 12.4 32.5 0.1 0.0 0.0 37.5 0.0 25.3 3.8 0.2 3.6 0.0 3.7 0.1 0.1 3.7 0.1 0.1 35.7 0.0 9.5 0.0 0.0 16.7 1.4 14.4 0.1 1.5 0.0 2.0 0.0 0.0 0.6 6.7 16.9 2.0 0.0 0.0 18.2 4.1 8.1 0.1 0.1 0.0 0.3 0.0 0.0 8.6 4.2 0.3 0.0 3.9 0.1 21.1 3.1 13.8 5.3 4.5 4.1 3.3 1.7 3.3 5.3 3.1 0.6 1.9 10.5 5.8 5.7 7.5 2.9 2.3 1.5 1.7 2.2 1.7 1.9 2.1 4.2 1.2 4.2 3.3 GALNT4 GalNAc-T4 ENSG00000257594 "Polypeptide N-acetylgalactosaminyltransferase 4" Q8N4A0 12 89519408-89524806 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "PC-3: 18.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA076116 Approved "Golgi apparatus" 270000 "Golgi apparatus" "HPA076116: " "unprognostic (2.96e-2)" "unprognostic (7.65e-3)" "unprognostic (8.76e-2)" "unprognostic (3.94e-5)" "unprognostic (3.50e-1)" "unprognostic (4.87e-2)" "unprognostic (2.02e-1)" "unprognostic (2.92e-2)" "unprognostic (2.78e-1)" "unprognostic (4.07e-2)" "unprognostic (1.28e-2)" "unprognostic (2.24e-1)" "unprognostic (5.81e-6)" "unprognostic (2.34e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-2)" "unprognostic (2.52e-1)" 5.0 2.4 4.0 5.8 3.2 3.9 2.6 1.4 3.4 11.1 14.3 3.7 2.7 11.1 9.5 1.9 3.7 7.7 15.8 2.9 1.9 1.7 8.3 5.6 3.2 1.7 4.4 1.1 4.3 8.6 1.1 5.9 2.9 3.7 2.9 11.4 3.3 22.6 1.2 1.1 1.8 20.8 2.0 2.6 7.5 21.0 1.4 3.7 0.2 2.7 2.0 8.2 4.1 2.8 2.8 3.4 5.9 7.5 7.3 5.8 2.7 2.5 7.7 2.7 14.9 5.5 7.9 1.9 6.2 2.9 2.5 2.7 3.0 4.8 0.0 1.5 4.6 4.0 0.8 4.1 4.3 6.5 1.7 3.1 1.4 2.3 2.6 2.8 7.0 3.6 1.8 5.2 2.3 8.1 1.9 1.4 3.9 1.9 0.2 5.5 1.8 18.5 0.6 0.5 1.2 7.6 8.0 0.1 1.2 0.8 4.2 5.7 8.2 2.8 7.5 5.3 1.9 3.2 2.0 1.3 2.2 1.2 2.7 1.4 3.0 5.9 5.2 2.4 3.2 7.4 5.8 1.9 1.8 2.4 3.4 2.8 2.6 2.3 5.0 7.3 7.5 1.2 1.9 2.7 4.0 3.2 1.4 3.4 1.9 1.7 4.4 1.1 3.7 3.7 GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257598-157314211 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2" "Cell line enhanced" "Detected in some" "A-431: 23.1;BJ: 15.2;BJ hTERT+: 27.2;fHDF/TERT166: 31.7;HaCaT: 27.1;K-562: 15.7;LHCN-M2: 27.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 6 "cerebellum: 28.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" 630000 "Nucleoli, Golgi apparatus, Cytosol" Vesicles "HPA008963: AB_1078942, HPA009035: AB_1078943" "unprognostic (6.34e-3)" "unprognostic (9.31e-2)" "unprognostic (2.11e-2)" "unprognostic (9.89e-2)" "unprognostic (3.19e-2)" "unprognostic (2.46e-2)" "unprognostic (4.63e-3)" "unprognostic (1.88e-1)" "unprognostic (1.09e-1)" "unprognostic (6.93e-2)" "unprognostic (4.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (6.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (9.48e-3)" 0.4 0.2 0.2 1.5 0.2 0.5 1.1 28.2 0.2 7.5 12.0 0.7 0.0 2.3 0.5 0.5 9.0 0.2 17.1 0.9 0.4 0.2 0.3 0.2 15.5 0.0 0.2 0.0 0.3 1.5 0.0 6.8 0.1 4.4 1.6 16.1 0.3 18.9 0.2 0.2 0.5 8.4 0.8 0.3 0.3 15.2 0.5 0.0 0.1 0.3 12.2 11.7 2.3 6.6 0.2 0.1 0.2 0.1 0.1 0.5 0.0 23.1 2.5 0.0 0.0 1.0 8.1 0.0 15.2 27.2 0.2 0.6 1.0 13.4 0.0 0.0 31.7 27.1 0.4 5.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.1 0.0 0.5 0.0 15.7 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.1 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.5 0.1 0.2 0.1 0.1 0.1 0.2 0.0 0.2 0.2 28.2 0.2 0.4 0.2 0.2 0.0 4.4 0.0 GALNT6 GalNAc-T6 ENSG00000139629 "Polypeptide N-acetylgalactosaminyltransferase 6" Q8NCL4 12 51351247-51392867 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 35.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 33.6;CACO-2: 33.2;SK-BR-3: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 23.8" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011762, HPA017086" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" 2900000 "Nucleoplasm, Golgi apparatus" "HPA011762: AB_1849450, HPA017086: AB_1849452" "unprognostic (2.03e-1)" "unprognostic (6.65e-2)" "unprognostic (2.26e-2)" "prognostic favourable (9.85e-4)" "unprognostic (1.35e-2)" "unprognostic (1.18e-1)" "unprognostic (7.15e-3)" "unprognostic (2.05e-1)" "unprognostic (2.27e-2)" "prognostic favourable (5.40e-4)" "unprognostic (1.88e-2)" "unprognostic (5.25e-2)" "unprognostic (7.13e-4)" "unprognostic (5.65e-3)" "unprognostic (3.18e-1)" "unprognostic (2.16e-2)" "unprognostic (1.18e-2)" 3.1 1.8 4.0 4.1 9.5 4.4 10.6 1.0 5.1 19.5 13.4 15.4 0.5 11.8 0.9 14.4 2.8 3.7 6.8 0.8 7.1 3.6 2.5 0.8 4.1 4.0 14.4 3.6 1.4 6.3 0.4 1.6 9.9 5.8 1.3 3.9 0.9 23.8 6.3 0.6 5.5 16.9 0.8 8.3 5.5 35.4 0.8 9.7 6.6 1.8 2.3 6.6 2.2 2.2 2.9 3.7 23.8 6.5 10.8 3.4 2.8 11.5 1.2 0.2 0.0 0.0 0.1 18.5 19.4 33.6 8.3 5.6 33.2 6.1 0.1 1.8 10.9 11.1 0.6 8.4 5.3 2.6 1.2 7.4 0.2 0.2 0.3 3.9 26.1 0.7 7.8 7.4 7.1 20.4 1.6 0.3 0.0 22.6 12.5 2.9 1.6 21.0 0.0 0.0 3.3 6.5 0.8 0.1 7.5 0.1 33.9 0.0 18.8 1.7 23.9 0.0 4.2 0.0 0.0 0.6 0.1 1.0 2.3 8.7 0.1 4.5 4.4 23.8 3.4 3.7 1.4 0.8 1.7 2.6 3.7 2.9 2.7 2.3 0.8 10.8 6.5 3.1 1.1 2.8 4.0 9.5 1.0 5.1 7.1 3.6 14.4 3.6 5.8 9.7 GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" "Q9NY28, P17658" 12 4720341-4851927 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Glycosyltransferase, Ion channel, Potassium channel, Transferase, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 12.7;intestine: 33.2;testis: 18.5" "Group enriched" "Detected in some" 4 "Karpas-707: 26.3;NTERA-2: 9.3;U-266/84: 7.5" "Cancer enhanced" "Detected in some" "testis cancer: 2.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 3.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012638, HPA073461" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: " "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" 1.1 2.2 5.3 2.2 6.5 0.5 3.1 1.4 12.7 1.0 15.5 9.4 0.0 7.2 0.9 0.4 0.7 1.2 1.1 3.7 8.0 1.7 1.2 0.8 0.9 1.0 5.7 9.6 1.6 0.9 0.2 3.7 0.5 6.0 1.1 33.2 0.1 1.0 0.9 0.7 0.9 14.7 2.1 3.5 1.2 1.3 18.5 11.5 0.0 0.8 0.5 0.9 1.2 0.9 1.0 0.7 0.1 0.1 0.9 3.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 26.3 0.0 0.0 0.2 0.1 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.3 7.5 0.7 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.4 0.3 0.7 1.2 0.0 1.0 0.0 0.1 0.1 0.9 0.0 0.7 3.0 0.0 5.3 6.5 1.4 12.7 8.0 1.7 5.7 9.6 6.0 11.5 GALNT9 GALNAC-T9 ENSG00000182870 "Polypeptide N-acetylgalactosaminyltransferase 9" Q9HCQ5 12 132196372-132329349 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 52.4" "Cell line enriched" "Detected in some" 5 "U-87 MG: 26.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 2.6;naive B-cell: 1.5" "Lineage enriched" "Detected in single" 9 "B-cells: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075016 Approved Vesicles Vesicles "HPA075016: " "unprognostic (1.13e-1)" "unprognostic (3.47e-2)" "unprognostic (1.47e-1)" "unprognostic (6.44e-2)" "unprognostic (1.03e-1)" "unprognostic (6.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.32e-2)" "unprognostic (2.03e-1)" "unprognostic (1.64e-3)" "unprognostic (2.85e-1)" "unprognostic (6.62e-2)" "unprognostic (5.17e-2)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (3.89e-2)" "unprognostic (5.69e-2)" 2.6 2.2 9.3 1.0 6.7 0.6 0.5 52.4 27.9 1.1 0.8 0.8 0.0 1.1 1.8 7.7 0.5 1.9 0.7 0.6 12.9 6.8 3.2 0.5 0.9 1.3 4.3 10.8 1.3 0.4 1.9 2.7 0.5 6.9 1.0 0.6 0.3 1.2 1.7 0.5 0.9 1.0 0.6 1.7 1.2 0.7 0.9 1.1 0.0 6.1 0.0 0.4 0.7 0.1 2.6 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 26.3 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 2.6 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.3 6.7 52.4 20.2 12.9 6.8 4.3 10.8 6.9 1.1 GALNTL6 "GalNAc-T6L, GALNT17" ENSG00000174473 "Polypeptide N-acetylgalactosaminyltransferase like 6" Q49A17 4 171812254-173041559 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 9.5;lymphoid tissue: 7.3;testis: 6.4" "Cell line enhanced" "Detected in some" "Karpas-707: 2.3;SCLC-21H: 2.4;SK-MEL-30: 1.9;U-266/70: 2.8;WM-115: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 4.5;naive B-cell: 1.6" "Lineage enriched" "Detected in single" 8 "B-cells: 4.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031019 Uncertain "Intracellular and membrane" "HPA031019: AB_10601653" "unprognostic (6.84e-2)" "unprognostic (1.28e-1)" "unprognostic (2.01e-2)" "unprognostic (5.73e-2)" "unprognostic (7.50e-2)" "unprognostic (8.32e-2)" "unprognostic (3.25e-1)" "unprognostic (9.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (2.80e-1)" "unprognostic (1.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-2)" "unprognostic (4.84e-3)" "unprognostic (1.73e-2)" 0.2 0.7 3.9 1.2 8.3 1.1 0.7 1.0 9.5 3.3 1.0 0.6 0.0 0.7 0.3 0.3 0.2 0.3 0.5 0.5 3.6 4.1 0.3 0.5 0.5 1.3 7.6 2.4 0.1 0.5 0.1 0.0 0.1 1.8 2.2 0.7 1.3 0.3 0.2 0.5 0.6 1.2 0.3 0.5 7.3 2.9 6.4 1.2 0.0 0.5 1.1 0.4 0.5 0.6 4.5 0.5 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.5 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.7 1.2 0.0 1.3 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.7 2.3 0.2 1.1 0.3 0.6 1.4 0.0 0.0 0.1 0.0 0.0 0.0 2.4 1.0 0.0 0.5 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.3 0.1 1.7 0.0 0.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 8.3 1.0 5.9 3.6 4.1 7.6 2.4 1.8 1.2 GALT ENSG00000213930 "Galactose-1-phosphate uridylyltransferase" P07902 9 34638133-34651035 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Nucleotidyltransferase, Transferase" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004868, HPA005729" Enhanced Approved Cytosol 120000 Cytosol "HPA004868: AB_1079130, HPA005729: AB_1079131" "unprognostic (2.38e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-3)" "unprognostic (1.54e-1)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (2.13e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-2)" "prognostic favourable (3.11e-5)" "unprognostic (9.68e-2)" "prognostic favourable (6.25e-6)" "unprognostic (7.90e-2)" "unprognostic (2.74e-1)" "unprognostic (3.56e-1)" "unprognostic (7.75e-2)" 6.3 16.1 8.0 13.8 12.5 7.4 6.6 9.3 7.3 8.5 19.4 5.8 12.4 18.1 7.2 8.4 7.7 6.5 10.5 10.9 6.7 8.6 11.8 47.0 6.8 10.8 9.0 6.0 8.7 7.6 12.1 10.3 21.7 7.5 7.2 6.8 11.0 12.5 13.4 9.5 14.4 26.1 5.9 5.0 9.4 8.1 2.6 7.1 11.3 8.5 7.2 10.6 7.0 6.5 16.3 15.9 10.9 17.5 20.5 21.1 13.1 4.9 6.6 6.0 2.4 8.3 8.3 7.0 3.7 10.6 3.9 4.4 8.2 4.6 5.6 3.8 4.4 2.7 1.1 10.3 0.7 8.3 4.5 2.3 13.2 8.3 8.1 1.3 2.9 12.1 6.6 2.5 3.1 9.3 1.9 6.1 6.2 4.3 4.7 9.4 2.1 1.2 7.3 5.5 2.9 10.7 6.9 1.4 5.3 4.7 9.3 5.0 8.3 7.2 1.4 1.7 3.2 3.3 0.0 3.5 2.0 1.1 4.0 3.9 9.8 10.9 17.5 8.3 12.1 15.0 16.7 16.3 19.8 16.3 15.9 9.3 12.2 12.0 3.3 20.5 14.1 13.3 21.1 13.1 8.0 12.5 9.3 7.3 6.7 8.6 9.0 6.0 7.5 7.1 GAMT "PIG2, TP53I2" ENSG00000130005 "Guanidinoacetate N-methyltransferase" Q14353 19 1397026-1401570 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 73.0;skeletal muscle: 222.2" "Cell line enhanced" "Detected in many" "Hep G2: 51.2" "Cancer enriched" "Detected in all" 5 "liver cancer: 173.2" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051806 Approved 38000 "HPA051806: " "unprognostic (3.25e-1)" "unprognostic (7.74e-3)" "unprognostic (3.22e-2)" "unprognostic (6.32e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (3.41e-2)" "unprognostic (7.10e-2)" "unprognostic (6.36e-2)" "prognostic unfavourable (6.57e-4)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.54e-2)" 5.1 4.6 9.1 1.5 8.7 2.2 3.2 5.1 11.4 2.3 1.4 15.1 5.1 1.3 2.0 31.3 5.3 3.8 2.6 10.8 9.2 7.7 8.0 73.0 1.5 2.0 8.7 5.2 3.8 47.0 5.4 4.9 1.6 5.9 5.6 1.1 4.5 9.1 4.7 222.2 6.0 1.4 2.1 8.8 2.1 3.2 7.7 4.5 5.6 3.3 26.7 2.8 1.9 1.7 15.7 23.0 6.9 2.6 8.0 21.6 7.7 6.2 7.1 7.6 17.2 9.6 11.7 10.4 7.5 12.5 9.7 8.8 16.0 4.5 3.3 5.3 8.9 2.7 12.0 4.6 2.6 23.8 13.7 10.2 5.9 51.2 5.7 0.2 3.5 13.0 1.6 10.3 0.0 2.1 14.5 8.0 15.8 6.4 29.8 3.5 8.6 22.6 29.9 6.8 23.8 11.4 5.8 2.5 17.9 0.5 4.3 9.2 19.8 14.2 3.6 10.7 11.1 0.6 3.4 36.3 7.0 5.6 9.9 13.5 12.2 1.6 1.2 6.9 9.9 1.6 13.9 10.6 13.7 12.2 5.4 15.7 21.6 16.1 0.8 8.0 2.6 23.0 7.5 7.7 9.1 8.7 5.1 11.4 9.2 7.7 8.7 5.2 5.9 4.5 GANAB "G2AN, GIIA, GluII, KIAA0088" ENSG00000089597 "Glucosidase II alpha subunit" Q14697 11 62624826-62646726 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026874, HPA061426" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" 37000000 "Endoplasmic reticulum" "HPA026874: AB_1849745, HPA061426: AB_2684516" "unprognostic (2.12e-1)" "unprognostic (5.95e-3)" "unprognostic (4.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "prognostic unfavourable (1.27e-5)" "unprognostic (5.80e-3)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.01e-3)" "unprognostic (3.81e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "prognostic unfavourable (9.54e-4)" 33.6 34.6 16.2 23.3 20.7 17.9 30.1 19.9 31.0 38.9 31.5 29.8 43.4 26.0 44.0 38.6 29.2 34.2 33.8 32.6 17.2 16.5 35.9 91.5 31.4 30.2 21.7 19.5 49.0 51.4 56.6 27.3 61.1 20.0 29.4 32.6 33.7 43.5 40.7 28.2 24.5 39.8 37.4 19.5 37.4 31.2 27.7 20.2 41.8 45.6 25.2 34.0 36.0 29.4 14.6 17.5 16.5 18.8 22.5 20.0 17.6 42.3 37.2 46.5 84.3 71.9 62.8 50.4 47.8 71.8 66.2 57.2 31.0 78.9 29.0 96.8 84.4 58.0 56.1 53.7 68.7 23.4 24.2 28.7 51.0 12.9 53.0 44.5 36.1 60.9 34.8 65.8 69.2 61.3 40.6 52.5 59.5 37.2 23.1 14.5 39.4 30.2 30.8 55.7 73.0 32.5 34.7 24.6 33.4 68.3 44.4 50.8 58.1 37.9 46.1 66.3 42.4 52.0 44.4 52.7 60.9 22.2 72.8 23.9 64.5 16.5 15.0 14.4 20.0 18.8 20.0 14.6 13.8 15.9 17.5 13.1 17.9 16.3 7.0 22.5 16.4 11.6 13.0 17.6 16.2 20.7 19.9 31.0 17.2 16.5 21.7 19.5 20.0 20.2 GANC ENSG00000214013 "Glucosidase alpha, neutral C" Q8TET4 15 42273233-42356935 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016949 Approved Approved "Nucleoplasm,Actin filaments" "Nucleoplasm, Actin filaments" "HPA016949: AB_1849465" "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (2.24e-1)" "unprognostic (3.04e-3)" "unprognostic (2.51e-2)" "unprognostic (9.85e-2)" "unprognostic (2.49e-2)" "prognostic favourable (9.76e-4)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (1.46e-1)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "unprognostic (3.14e-1)" "unprognostic (1.55e-2)" "unprognostic (3.74e-2)" 13.3 14.0 12.5 17.3 20.7 17.6 14.4 16.6 14.2 15.8 14.3 25.6 15.4 11.7 17.9 26.0 20.7 12.9 13.0 12.4 13.4 10.4 13.5 18.0 30.5 13.8 25.0 13.7 18.8 13.1 17.4 20.5 10.8 19.8 13.1 17.8 18.3 20.4 13.7 23.9 13.9 15.4 15.9 25.1 15.5 13.1 24.5 22.6 17.4 16.8 12.3 18.3 16.2 16.3 17.6 12.2 9.3 10.1 4.0 7.4 4.7 6.1 3.2 7.9 8.5 9.6 13.5 5.0 13.6 14.7 15.0 12.6 4.7 4.4 3.4 7.4 13.7 12.9 9.4 14.5 10.4 8.4 4.3 8.4 8.5 9.1 8.1 8.1 7.3 9.1 8.7 6.1 10.4 10.1 8.7 9.5 11.8 1.3 5.4 9.0 4.8 4.1 10.5 9.2 11.7 11.3 5.8 5.9 8.4 7.6 6.7 4.8 2.5 19.3 9.2 15.8 4.2 13.0 8.1 10.3 13.6 6.9 7.4 15.0 8.7 9.3 9.3 7.4 3.7 10.1 5.0 16.2 5.7 6.9 12.2 17.6 7.4 4.4 5.0 4.0 8.1 9.6 5.5 4.7 12.5 20.7 16.6 14.2 13.4 10.4 25.0 13.7 19.8 22.6 GAPDH GAPD ENSG00000111640 "Glyceraldehyde-3-phosphate dehydrogenase" P04406 12 6533927-6538374 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Glycolysis, Translation regulation" "Oxidoreductase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 1236.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB005197, CAB016392, HPA040067, HPA061280" Supported Supported "Nuclear membrane,Vesicles,Plasma membrane,Cytosol" 2200000000 "Plasma membrane, Cytosol" "Nuclear membrane, Vesicles" "CAB005197: AB_641107, CAB016392: AB_627678, HPA040067: AB_10965903, HPA061280: AB_2684463" "unprognostic (3.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.58e-2)" "unprognostic (4.20e-1)" "unprognostic (9.73e-3)" "unprognostic (1.77e-3)" "prognostic unfavourable (1.79e-6)" "unprognostic (2.89e-3)" "unprognostic (2.86e-1)" "unprognostic (2.06e-2)" "unprognostic (9.50e-3)" "unprognostic (4.52e-1)" "prognostic unfavourable (6.25e-10)" "unprognostic (2.33e-1)" "unprognostic (4.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.26e-2)" 50.0 59.4 104.1 57.6 101.0 195.5 38.4 58.0 151.3 49.4 73.3 80.7 24.0 75.8 37.3 46.8 146.9 50.2 58.0 215.1 95.0 95.5 88.4 221.0 41.3 90.1 111.8 58.0 62.0 27.0 66.1 46.1 98.2 115.9 48.3 76.7 74.5 60.8 63.2 1236.8 54.4 74.4 68.0 95.6 50.7 41.1 36.4 35.9 101.9 38.3 238.7 105.3 89.5 50.5 57.9 171.0 110.0 201.6 60.5 108.8 271.9 196.0 345.9 99.8 155.5 97.4 160.6 217.5 149.0 212.2 218.1 227.7 244.1 134.6 229.2 29.5 175.6 111.7 92.7 345.6 151.4 201.0 100.7 126.8 217.1 207.3 131.3 204.9 102.1 134.3 112.9 214.3 242.1 240.0 68.1 48.3 247.7 391.1 233.5 107.9 368.8 115.3 189.9 177.7 109.1 248.1 239.9 70.7 113.5 131.5 343.1 197.9 53.6 144.8 149.7 170.2 205.7 87.8 257.4 109.8 79.8 295.4 360.8 129.9 266.3 110.0 201.6 37.0 74.1 103.2 65.3 57.9 77.9 74.4 171.0 32.2 44.1 51.2 106.5 60.5 92.3 25.2 108.8 271.9 104.1 101.0 58.0 151.3 95.0 95.5 111.8 58.0 115.9 35.9 GAPDHS "GAPD2, GAPDH-2, GAPDS" ENSG00000105679 "Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic" O14556 19 35533412-35545316 "Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "testis: 154.6" "Cell line enhanced" "Detected in many" "A549: 16.2" "Cancer enriched" "Detected in single" 97 "melanoma: 13.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042666 Enhanced Approved Nucleoplasm,Centrosome Nucleoplasm Centrosome "HPA042666: " "unprognostic (3.74e-1)" "unprognostic (1.59e-1)" "unprognostic (7.41e-2)" "unprognostic (1.56e-1)" "unprognostic (2.06e-1)" "unprognostic (1.04e-1)" "unprognostic (8.81e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.37e-1)" 0.3 0.5 0.3 0.8 0.3 0.2 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.6 0.5 1.6 0.6 0.2 0.8 0.8 0.3 0.3 0.3 0.3 0.3 1.6 0.3 0.3 0.7 1.3 0.0 0.3 0.3 0.3 0.3 0.0 4.2 1.3 0.3 0.3 4.4 0.6 0.3 0.3 1.2 0.4 154.6 0.3 0.3 3.6 0.3 0.3 0.6 0.3 2.1 1.0 1.2 0.8 1.4 2.0 0.8 4.4 16.2 4.5 6.8 0.0 0.0 3.8 1.3 0.0 0.0 0.0 9.8 7.4 7.4 2.1 0.0 5.4 0.0 0.0 0.0 7.2 7.9 4.9 10.3 5.0 0.1 4.4 5.9 0.0 0.0 0.0 0.0 0.0 11.8 4.4 0.0 13.8 1.7 2.1 6.1 2.2 5.2 3.2 5.7 0.0 4.4 8.1 3.7 1.6 4.1 4.8 3.4 1.9 1.5 5.2 5.8 1.3 1.8 12.1 3.2 4.3 2.8 8.0 1.9 0.0 0.8 1.2 1.1 0.6 2.0 1.1 0.4 1.9 1.0 2.1 1.1 1.2 0.0 1.4 0.3 0.8 0.3 0.8 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 GARS "CMT2D, DSMAV, GlyRS, SMAD1" ENSG00000106105 "Glycyl-tRNA synthetase" P41250 7 30594681-30634033 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Hydrolase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017896, HPA019097" Enhanced Supported Cytosol "Intracellular and membrane" 660000 Cytosol "HPA017896: AB_1849478, HPA019097: AB_1849480" "prognostic unfavourable (1.02e-4)" "unprognostic (2.46e-2)" "unprognostic (5.45e-2)" "prognostic unfavourable (8.48e-4)" "unprognostic (2.04e-1)" "unprognostic (1.57e-3)" "prognostic unfavourable (8.95e-5)" "unprognostic (7.31e-3)" "unprognostic (4.76e-1)" "unprognostic (4.00e-3)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "prognostic unfavourable (1.70e-5)" "unprognostic (3.92e-1)" "unprognostic (3.40e-2)" "unprognostic (6.32e-2)" "prognostic unfavourable (3.04e-5)" 25.8 27.3 24.5 26.2 28.5 24.6 32.4 31.1 44.7 21.5 23.7 17.0 11.5 17.2 24.1 23.3 43.7 18.6 18.4 25.7 21.1 26.8 27.6 57.2 27.9 28.0 22.9 28.4 35.4 49.4 44.4 33.3 24.3 37.6 17.2 30.2 14.1 28.7 21.6 35.6 33.2 18.1 30.1 17.6 23.5 30.5 29.7 14.9 28.6 31.4 33.9 38.4 22.8 25.7 22.5 26.4 21.2 27.2 15.3 27.6 21.2 33.0 16.4 14.5 51.5 27.2 40.9 27.6 49.5 44.8 25.5 51.7 21.8 16.5 55.7 14.9 60.2 26.2 36.2 31.4 44.9 13.3 16.9 25.7 13.4 18.3 86.4 37.8 22.8 38.9 55.2 36.6 43.5 32.7 50.9 64.9 40.4 20.3 32.9 26.2 39.2 31.4 16.7 12.8 43.2 29.2 14.9 17.6 29.4 13.2 37.0 70.3 33.0 58.0 30.0 12.1 40.7 24.3 31.2 64.2 53.8 65.5 42.3 57.3 56.9 21.2 19.0 17.7 23.2 25.8 23.7 22.5 23.7 25.1 26.4 19.3 25.5 27.6 5.6 15.3 27.2 18.0 25.9 21.2 24.5 28.5 31.1 44.7 21.1 26.8 22.9 28.4 37.6 14.9 GART "GARS-AIRS-GART, PGFT, PRGS" ENSG00000159131 "Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" P22102 21 33503931-33543491 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Ligase, Multifunctional enzyme, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002119, HPA005779" Approved Uncertain Nucleoplasm,Mitochondria,Cytosol 1300000 "Nucleoplasm, Mitochondria, Cytosol" "HPA002119: AB_1849482, HPA005779: AB_1849484" "unprognostic (3.77e-2)" "unprognostic (2.25e-2)" "unprognostic (4.51e-3)" "unprognostic (1.72e-2)" "unprognostic (2.30e-2)" "prognostic unfavourable (5.05e-5)" "prognostic unfavourable (9.82e-5)" "unprognostic (2.50e-2)" "unprognostic (2.76e-3)" "unprognostic (2.92e-1)" "prognostic unfavourable (2.19e-4)" "unprognostic (1.98e-3)" "prognostic unfavourable (3.95e-6)" "unprognostic (1.36e-2)" "unprognostic (2.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" 24.9 24.7 16.0 20.0 22.3 14.2 22.2 14.5 20.3 16.2 20.1 20.5 13.3 18.9 21.7 15.9 28.1 19.9 14.3 19.3 16.4 14.9 19.2 33.6 18.3 24.4 21.9 14.6 21.0 30.6 21.6 22.9 23.1 21.0 16.4 26.9 19.5 18.6 16.1 33.2 17.6 19.1 23.5 17.9 21.4 21.9 47.0 21.7 40.8 20.0 19.4 32.8 21.6 17.6 18.7 19.5 9.7 20.9 27.1 21.1 13.3 30.0 14.3 21.2 23.5 15.6 16.1 23.8 19.5 16.5 22.8 24.2 27.1 25.6 40.0 11.6 13.0 15.9 44.4 30.6 33.3 21.0 26.4 60.3 17.1 17.7 21.3 33.5 15.9 14.2 21.4 26.9 39.6 21.5 70.1 25.7 20.6 14.4 35.3 22.5 46.2 16.9 29.5 39.5 56.6 18.3 16.1 22.6 20.3 27.0 21.3 25.2 27.0 21.5 15.8 15.5 18.6 13.4 20.8 25.6 35.4 43.7 16.3 39.5 22.9 5.3 15.2 9.7 17.3 20.9 21.1 18.7 16.9 17.9 19.5 14.4 17.7 17.4 7.0 27.1 17.7 14.7 20.6 13.3 16.0 22.3 14.5 20.3 16.4 14.9 21.9 14.6 21.0 21.7 GATD1 "FLJ34283, PDDC1" ENSG00000177225 "Glutamine amidotransferase like class 1 domain containing 1" Q8NB37 11 767220-777488 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008812 Uncertain Supported Nucleoplasm "Secreted - unknown location" Nucleoplasm "HPA008812: AB_10962724" "unprognostic (3.39e-1)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" "unprognostic (3.58e-2)" "unprognostic (2.82e-2)" "unprognostic (3.03e-2)" "prognostic unfavourable (3.98e-4)" "unprognostic (3.50e-2)" "unprognostic (2.19e-1)" "unprognostic (5.67e-2)" "unprognostic (5.23e-3)" "unprognostic (4.89e-3)" "prognostic favourable (3.79e-5)" "unprognostic (2.84e-2)" "unprognostic (8.40e-2)" "unprognostic (6.11e-2)" "unprognostic (6.61e-3)" 16.7 36.5 26.6 16.3 24.9 10.6 19.1 30.9 29.8 15.1 15.0 20.7 19.8 23.3 17.7 22.4 16.6 18.8 20.0 16.7 27.0 26.2 19.8 18.6 15.3 15.6 25.8 19.4 21.9 16.6 15.5 22.9 16.4 22.0 18.6 10.5 15.8 20.0 23.8 19.2 27.2 21.5 12.6 21.7 17.2 19.1 17.5 21.5 12.8 17.0 13.0 11.5 11.9 14.3 4.0 9.5 1.3 8.7 1.7 4.7 2.8 16.5 9.6 9.3 9.9 4.3 6.7 9.0 9.9 4.3 9.2 8.1 6.9 26.0 9.0 3.6 6.5 17.8 6.9 8.8 4.6 11.5 49.8 5.5 14.4 14.5 7.5 10.3 11.8 9.5 9.8 3.9 6.0 7.0 13.5 8.3 5.1 4.8 11.6 11.1 8.8 17.7 12.8 6.3 11.3 8.0 3.7 24.0 9.4 9.6 13.6 6.7 11.8 6.8 12.8 9.9 7.5 5.3 7.6 10.0 5.0 11.5 15.0 13.8 8.0 1.3 7.0 1.3 4.7 8.7 3.4 4.0 4.5 4.4 9.5 3.5 3.9 2.6 0.7 1.7 3.5 5.5 2.1 2.8 26.6 24.9 30.9 27.7 27.0 26.2 25.8 19.4 22.0 21.5 GATM AGAT ENSG00000171766 "Glycine amidinotransferase" P50440 15 45361124-45402327 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "kidney: 186.3;liver: 252.2;pancreas: 286.1" "Group enriched" "Detected in some" 4 "RH-30: 55.9;RT4: 14.7;U-266/70: 34.5;U-266/84: 43.6" "Cancer enhanced" "Detected in all" "liver cancer: 135.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 12.8;myeloid DC: 6.9;naive B-cell: 5.9;plasmacytoid DC: 6.8" "Group enriched" "Detected in many" 6 "B-cells: 12.8;dendritic cells: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026077 Enhanced Supported Mitochondria 620000 Mitochondria "HPA026077: AB_1849528" "unprognostic (1.91e-1)" "unprognostic (1.33e-2)" "unprognostic (2.77e-2)" "unprognostic (6.57e-2)" "unprognostic (9.43e-2)" "unprognostic (1.67e-2)" "unprognostic (6.99e-3)" "unprognostic (1.04e-1)" "unprognostic (4.51e-2)" "unprognostic (3.36e-2)" "unprognostic (1.33e-1)" "unprognostic (5.67e-2)" "prognostic favourable (1.38e-4)" "unprognostic (1.09e-1)" "unprognostic (4.07e-2)" "unprognostic (3.60e-2)" "unprognostic (1.80e-1)" 1.8 2.5 18.5 1.6 14.7 0.6 2.9 11.4 16.2 1.5 3.1 24.9 0.3 17.8 1.3 2.2 3.0 1.7 5.0 5.5 15.2 10.3 186.3 252.2 1.2 2.1 20.6 14.3 17.6 286.1 0.7 1.2 7.8 14.5 1.7 1.7 1.5 5.5 2.1 13.5 13.9 10.8 2.7 26.1 3.5 10.0 8.0 18.4 0.7 6.6 2.5 3.1 2.2 2.0 12.8 6.9 0.3 1.5 0.1 1.5 0.8 3.4 1.7 1.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 5.7 8.8 0.3 0.0 0.6 4.4 0.1 0.1 0.4 0.0 0.7 0.0 0.0 0.2 5.1 0.7 0.2 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.6 0.1 3.1 0.0 0.1 55.9 0.4 0.9 14.7 6.5 1.1 1.8 0.1 0.3 0.7 5.8 0.0 0.0 0.1 0.0 1.7 34.5 43.6 0.2 0.4 0.1 0.3 0.0 1.1 0.3 0.3 1.5 0.0 12.8 0.0 0.3 6.9 5.9 0.0 1.5 0.0 0.1 0.6 6.8 0.0 0.8 18.5 14.7 11.4 16.2 15.2 10.3 20.6 14.3 14.5 18.4 GBA "GBA1, GLUC" ENSG00000177628 "Glucosylceramidase beta" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease mutation, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 101.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" 200000 "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" 19.2 29.7 14.8 13.9 24.5 21.9 15.3 8.7 33.4 16.5 20.1 25.2 18.1 13.8 16.9 30.4 18.9 12.7 16.5 13.6 15.8 18.9 31.8 24.6 17.9 15.4 18.5 16.5 13.1 19.2 101.2 32.1 46.2 28.1 14.4 23.5 25.3 22.3 24.3 6.0 21.6 16.6 17.7 19.3 24.5 14.6 9.7 13.1 13.7 22.2 8.7 17.5 16.3 15.2 7.3 13.9 17.9 22.3 6.6 14.0 12.4 8.5 16.5 5.9 8.0 61.7 13.6 6.8 15.1 53.7 22.5 28.5 9.6 31.3 5.9 16.8 35.3 17.3 8.3 10.7 12.0 12.4 5.8 4.9 10.9 5.2 17.7 5.8 20.6 17.8 9.0 47.3 7.2 20.0 5.1 10.0 26.4 18.5 7.1 2.6 3.7 11.7 6.0 9.6 24.2 15.1 6.6 5.6 7.7 13.2 31.7 33.4 23.8 14.1 15.1 17.0 7.6 21.3 12.0 20.0 16.9 4.6 29.7 5.3 13.0 12.2 21.6 9.1 13.4 22.3 8.7 7.3 10.3 9.0 13.9 5.5 7.4 7.8 17.9 6.6 21.2 7.8 14.0 12.4 14.8 24.5 8.7 33.4 15.8 18.9 18.5 16.5 28.1 13.1 GBA2 "AD035, DKFZp762K054, KIAA1605, SPG46" ENSG00000070610 "Glucosylceramidase beta 2" Q9HCG7 9 35736866-35749228 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024026 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Golgi apparatus" Cytosol "HPA024026: AB_1849530" "unprognostic (3.34e-2)" "unprognostic (2.90e-1)" "unprognostic (2.99e-1)" "unprognostic (1.06e-2)" "unprognostic (1.41e-1)" "unprognostic (5.83e-3)" "unprognostic (2.20e-2)" "unprognostic (2.09e-2)" "unprognostic (3.99e-2)" "unprognostic (8.69e-2)" "prognostic favourable (6.00e-4)" "unprognostic (9.01e-3)" "prognostic favourable (1.24e-11)" "unprognostic (7.62e-3)" "unprognostic (2.94e-1)" "unprognostic (7.69e-2)" "prognostic favourable (6.60e-4)" 15.6 19.3 28.9 17.0 23.3 11.0 24.3 42.3 41.6 14.8 35.1 17.0 28.4 41.5 19.0 22.3 16.6 16.8 21.4 34.6 22.4 21.0 34.8 25.0 20.9 17.3 23.7 19.5 16.4 20.9 27.9 27.1 19.3 36.6 23.9 32.8 28.4 27.7 25.5 46.1 23.5 51.1 23.3 21.0 23.4 26.9 11.6 19.5 10.9 25.4 15.5 16.4 18.2 16.9 5.6 6.8 12.2 6.1 3.1 7.3 3.1 8.1 13.5 18.7 18.1 9.1 5.6 19.0 11.1 8.8 11.4 12.0 15.0 6.5 8.8 8.1 6.7 8.6 17.9 7.5 5.7 12.4 12.2 9.4 35.4 16.1 10.1 14.0 23.5 9.6 14.1 9.6 10.1 29.7 9.2 16.9 10.5 8.1 3.8 14.5 19.4 21.5 7.0 7.5 7.4 15.8 19.3 15.3 20.5 6.2 15.7 11.0 10.7 12.7 20.6 12.3 14.9 10.5 13.5 11.5 7.3 7.3 15.5 5.1 9.5 12.2 4.4 2.9 6.0 6.1 4.1 5.0 5.8 7.3 4.2 5.6 3.7 3.2 4.9 3.1 3.7 6.8 4.0 3.1 28.9 23.3 42.3 41.6 22.4 21.0 23.7 19.5 36.6 19.5 GBE1 ENSG00000114480 "1,4-alpha-glucan branching enzyme 1" Q04446 3 81489699-81762161 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Glycosyltransferase, Transferase" "Disease mutation, Glycogen storage disease, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 56.9" "Cell line enhanced" "Detected in all" "ASC diff: 60.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038073, HPA038074, HPA038075" Enhanced Approved Nucleoplasm,Cytosol 5900000 "Nucleoplasm, Cytosol" "HPA038073: AB_10673040, HPA038074: AB_10672403, HPA038075: AB_10674545" "unprognostic (3.10e-1)" "unprognostic (1.02e-3)" "unprognostic (6.76e-2)" "unprognostic (1.05e-2)" "unprognostic (3.48e-2)" "unprognostic (1.89e-1)" "unprognostic (9.01e-3)" "unprognostic (1.17e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (2.19e-2)" "unprognostic (5.68e-2)" "unprognostic (1.46e-1)" "unprognostic (5.36e-2)" "unprognostic (4.42e-1)" "unprognostic (2.83e-3)" "unprognostic (3.78e-3)" 23.1 22.4 2.2 7.8 4.2 5.6 19.2 4.2 4.6 6.4 7.7 5.2 5.2 4.1 8.4 4.9 7.5 4.9 11.5 19.7 3.6 4.3 14.0 36.3 11.3 7.5 7.9 3.4 8.2 5.7 8.2 11.6 11.4 8.4 5.7 4.5 9.9 8.0 10.1 56.9 5.9 6.3 7.2 6.1 8.0 4.5 4.6 4.1 5.4 6.5 11.2 4.5 9.6 10.0 11.6 13.6 14.5 11.4 13.0 7.2 6.1 12.0 7.3 2.4 34.6 60.9 46.3 4.4 20.0 28.6 12.0 20.4 1.4 3.1 13.5 8.8 24.6 1.4 2.0 9.2 28.3 6.3 1.1 4.2 15.1 4.5 41.9 14.1 3.7 34.1 6.9 19.3 19.9 26.6 3.2 7.8 39.0 3.5 2.3 16.8 2.4 11.1 4.4 11.0 15.8 8.5 4.1 1.2 1.6 13.0 3.8 4.1 2.7 11.7 37.0 24.9 5.8 17.4 18.5 35.7 4.1 4.9 40.5 9.5 10.1 6.3 11.4 14.5 5.6 10.4 5.4 11.0 6.0 5.9 13.6 11.6 7.0 7.2 11.0 13.0 10.8 4.5 5.0 6.1 2.2 4.2 4.2 4.6 3.6 4.3 7.9 3.4 8.4 4.1 GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 81.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA020460 Uncertain Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA020460: AB_1849548" "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-2)" "unprognostic (4.17e-2)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (3.56e-2)" "unprognostic (2.76e-3)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-3)" "unprognostic (8.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.73e-3)" "unprognostic (3.99e-1)" 2.9 6.0 8.9 2.4 8.8 8.1 4.2 8.3 12.3 4.5 4.7 5.2 8.0 3.5 3.0 4.0 6.3 3.9 6.0 21.5 8.6 8.4 8.1 19.1 2.3 2.1 10.1 7.4 4.0 81.6 3.5 3.7 2.2 7.4 12.2 3.5 4.3 12.0 5.0 10.3 3.2 3.2 3.1 6.3 1.1 4.4 5.9 4.3 2.8 10.7 9.3 4.3 3.3 2.2 0.3 2.5 0.8 1.3 2.3 7.1 2.8 8.7 2.3 5.9 33.6 12.2 9.9 4.1 12.6 13.3 9.6 8.2 5.1 1.0 2.7 5.9 5.6 5.1 5.9 8.9 2.2 1.2 10.7 6.1 7.3 20.1 19.9 10.8 8.0 11.6 5.4 6.3 14.0 7.8 15.6 3.2 4.5 7.7 11.3 20.0 2.5 9.4 11.9 1.2 16.1 12.1 6.9 12.2 8.3 9.8 15.9 6.7 12.8 5.3 5.9 9.7 5.3 6.4 4.3 10.7 5.2 5.7 6.7 10.1 10.1 0.2 1.3 0.8 1.5 1.2 0.6 0.3 3.4 1.0 2.4 0.1 7.1 2.9 0.6 2.3 0.8 2.5 3.3 2.8 8.9 8.8 8.3 12.3 8.6 8.4 10.1 7.4 7.4 4.3 GCDH ACAD5 ENSG00000105607 "Glutaryl-CoA dehydrogenase" Q92947 19 12891026-12914207 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 62.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043252, HPA048492" Enhanced Supported Mitochondria Mitochondria "HPA043252: AB_2678390, HPA048492: AB_2680418" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" "unprognostic (6.79e-3)" "unprognostic (8.07e-3)" "unprognostic (8.20e-3)" "unprognostic (3.14e-2)" "prognostic favourable (7.28e-5)" "prognostic favourable (3.35e-4)" "unprognostic (1.62e-1)" "unprognostic (3.03e-2)" "unprognostic (7.50e-3)" "unprognostic (7.46e-2)" "prognostic favourable (6.79e-8)" "unprognostic (7.09e-3)" "unprognostic (3.42e-1)" "unprognostic (5.32e-2)" "unprognostic (1.59e-1)" 12.5 12.1 11.4 8.6 13.3 8.2 9.5 11.5 14.0 9.5 10.5 15.5 8.6 9.1 11.7 7.3 9.1 10.5 7.5 19.8 9.3 8.0 20.2 62.6 6.3 12.1 15.5 14.1 13.7 12.3 7.9 8.7 4.9 9.7 10.4 6.9 9.6 14.7 9.7 17.5 6.6 8.1 8.2 8.7 8.6 11.3 4.9 11.8 13.0 10.9 13.7 9.0 12.0 6.6 10.9 14.5 7.2 8.1 21.7 20.6 12.3 11.2 6.2 6.7 12.4 9.9 4.9 6.2 8.4 5.0 9.8 7.4 11.5 4.8 16.3 15.8 4.6 7.1 9.3 7.2 4.9 14.0 9.9 10.4 10.9 14.1 11.3 19.6 8.3 6.3 9.0 6.9 7.5 8.4 25.3 5.1 4.8 12.3 23.0 17.2 7.6 16.2 22.0 6.9 31.6 5.7 5.1 14.9 9.0 11.8 10.3 7.2 8.0 13.0 5.9 8.0 6.0 14.8 8.0 27.3 13.8 17.1 5.6 22.5 6.9 7.2 8.1 4.6 11.7 7.1 11.6 10.7 15.0 13.7 14.5 10.9 20.6 15.5 2.0 21.7 5.3 8.6 12.5 12.3 11.4 13.3 11.5 14.0 9.3 8.0 15.5 14.1 9.7 11.8 GCH1 "DYT14, DYT5, DYT5a, GCH, GTPCH1" ENSG00000131979 "GTP cyclohydrolase 1" P30793 14 54842008-54902852 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" "Allosteric enzyme, Hydrolase" "Disease mutation, Dystonia, Parkinsonism, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.8;liver: 58.2" "Cell line enhanced" "Detected in many" "BEWO: 11.6;Daudi: 13.2;SH-SY5Y: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 11.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "midbrain: 15.7" HPA028612 Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" Nucleoplasm "Nuclear membrane, Cytosol" "HPA028612: AB_10602135" "unprognostic (3.77e-2)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (2.39e-1)" "unprognostic (9.26e-2)" "unprognostic (1.27e-1)" "unprognostic (7.26e-2)" "unprognostic (1.75e-1)" "unprognostic (3.97e-1)" "prognostic favourable (8.69e-4)" "prognostic favourable (1.41e-4)" "unprognostic (1.23e-1)" "unprognostic (1.96e-2)" "unprognostic (7.22e-3)" "unprognostic (1.76e-2)" "unprognostic (2.23e-1)" "prognostic favourable (6.67e-4)" 4.8 5.2 1.3 5.7 4.5 26.8 2.1 0.6 1.1 2.2 5.5 1.2 1.5 7.5 1.8 1.9 3.8 1.3 1.6 1.5 1.6 4.3 7.9 58.2 11.6 6.7 2.9 0.7 1.4 3.2 0.3 2.5 2.5 2.8 2.9 4.0 5.2 2.5 4.7 1.4 2.5 9.1 2.0 1.7 10.0 4.2 3.6 1.1 13.0 2.3 2.0 8.5 2.9 2.5 1.6 3.0 0.4 11.5 2.3 3.2 1.3 1.9 0.6 0.7 3.5 0.0 0.0 11.6 0.0 1.2 0.8 2.2 0.9 0.6 13.2 3.3 0.1 2.0 5.7 0.9 0.0 5.1 4.9 0.3 0.2 1.9 5.6 0.0 1.2 1.4 1.6 1.9 0.0 0.4 0.8 0.0 0.0 6.8 7.1 0.2 1.1 4.5 5.8 1.4 0.0 1.6 2.7 5.8 29.3 2.4 1.5 0.7 5.6 1.6 0.2 0.1 1.9 3.7 2.3 5.6 4.2 3.2 2.4 4.5 0.0 0.0 3.0 0.2 3.0 6.3 2.5 0.8 1.6 2.1 3.0 1.6 3.2 1.8 0.4 2.3 11.5 0.1 2.3 1.3 1.3 4.5 0.6 1.1 1.6 4.3 2.9 0.7 2.8 1.1 GCK "HK4, MODY2" ENSG00000106633 Glucokinase P35557 7 44144271-44198170 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pituitary gland: 46.8" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 12.0" "Cancer enhanced" "Detected in some" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 4.4;naive CD4 T-cell: 4.8" "Group enriched" "Detected in many" 17 "B-cells: 4.4;T-cells: 4.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA007034, HPA007093" Approved Approved "Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" "HPA007034: AB_1079050, HPA007093: AB_1079051" "unprognostic (3.09e-1)" "unprognostic (2.99e-2)" "unprognostic (3.32e-2)" "unprognostic (6.64e-7)" "unprognostic (8.00e-2)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-1)" "unprognostic (5.48e-2)" "unprognostic (8.11e-3)" "unprognostic (3.08e-1)" "unprognostic (3.79e-3)" "unprognostic (2.01e-2)" "unprognostic (3.24e-1)" "unprognostic (4.36e-2)" "unprognostic (1.53e-1)" 1.1 0.5 3.2 0.7 2.8 0.0 0.7 9.5 3.7 1.4 1.4 1.3 0.7 0.3 1.5 1.5 0.7 2.3 0.9 7.1 2.1 7.5 0.7 8.7 0.7 0.7 2.9 1.2 2.2 2.9 0.0 46.8 3.3 1.6 0.8 0.5 0.8 0.7 1.6 0.7 1.2 0.7 0.7 1.7 0.7 0.9 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.9 4.4 0.2 0.0 0.0 0.0 4.8 0.7 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.6 0.3 0.0 0.0 0.0 0.1 0.8 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.6 0.9 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 2.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.1 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.6 4.4 1.6 0.4 0.2 0.7 4.8 0.9 0.0 0.0 0.0 0.0 0.0 0.7 3.2 2.8 9.5 2.4 2.1 7.5 2.9 1.2 1.6 0.7 GCLC "GCS, GLCL, GLCLC" ENSG00000001084 "Glutamate-cysteine ligase catalytic subunit" P48506 6 53497341-53616970 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell line enhanced" "Detected in all" "A549: 54.7;Hep G2: 46.7;RT4: 50.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 8.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009569, HPA036359, HPA036360" Approved Approved Nucleoplasm,Nucleoli,Cytosol 3600000 Nucleoplasm "Nucleoli, Cytosol" "CAB009569: AB_675582, HPA036359: AB_10672243, HPA036360: AB_10669789" "unprognostic (8.41e-2)" "unprognostic (1.27e-2)" "unprognostic (5.65e-2)" "unprognostic (2.42e-1)" "unprognostic (1.58e-1)" "unprognostic (2.76e-1)" "unprognostic (2.60e-1)" "unprognostic (7.50e-2)" "unprognostic (9.94e-3)" "unprognostic (4.67e-3)" "unprognostic (1.30e-1)" "unprognostic (5.23e-2)" "prognostic favourable (3.83e-6)" "unprognostic (3.78e-2)" "unprognostic (8.91e-2)" "prognostic unfavourable (8.24e-4)" "unprognostic (2.30e-2)" 15.8 11.1 12.9 9.0 16.0 14.4 13.0 5.4 15.1 6.8 16.2 21.6 8.2 18.9 9.2 5.3 20.0 29.1 14.9 7.4 13.1 10.6 15.4 69.2 12.9 10.1 21.6 12.2 6.2 12.4 6.6 5.4 6.2 13.0 13.0 12.2 5.2 11.2 10.1 7.0 8.6 14.8 11.9 13.6 16.8 14.8 5.2 17.5 3.1 14.1 32.4 10.6 34.4 12.3 1.6 4.2 2.2 1.9 8.0 2.3 0.6 8.1 54.7 4.5 10.6 5.4 2.4 6.0 4.1 6.7 3.1 3.7 8.0 19.0 15.5 7.9 3.7 11.6 13.7 30.1 4.2 12.2 8.4 10.4 10.6 46.7 6.2 13.6 6.4 3.8 12.8 3.5 15.7 4.7 5.7 4.9 1.5 8.6 11.7 5.4 8.3 5.1 3.9 2.7 13.7 10.1 50.4 13.0 6.4 6.9 11.1 7.2 7.6 6.5 6.5 2.8 9.8 7.1 6.1 6.6 10.1 9.0 7.0 9.8 4.7 2.2 1.1 0.6 1.2 1.9 0.8 1.6 1.0 2.3 4.2 1.0 0.6 1.3 0.5 8.0 1.8 3.0 1.6 0.6 12.9 16.0 5.4 11.9 13.1 10.6 21.6 12.2 13.0 17.5 GCNT1 "C2GNT, NACGT2, NAGCT2" ENSG00000187210 "Glucosaminyl (N-acetyl) transferase 1, core 2" Q02742 9 76419850-76507416 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.0;parathyroid gland: 57.8" "Cell line enhanced" "Detected in many" "HHSteC: 25.8;HSkMC: 21.9;U-2197: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 16.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "cerebellum: 8.2;olfactory region: 30.1" "Low region specificity" "Detected in all" "HPA003522, HPA003523, HPA031151" Uncertain Supported "Nuclear speckles" 72000 "Nuclear speckles" "HPA003522: , HPA003523: , HPA031151: AB_10602904" "unprognostic (3.14e-1)" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "prognostic favourable (8.44e-4)" "unprognostic (5.53e-2)" "unprognostic (2.41e-1)" "unprognostic (1.65e-2)" "unprognostic (3.37e-2)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.90e-1)" "unprognostic (3.06e-1)" "unprognostic (3.02e-3)" "unprognostic (4.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.80e-1)" "prognostic unfavourable (4.96e-4)" 5.6 1.1 1.6 7.9 3.9 2.2 8.2 10.9 2.7 5.3 24.5 0.7 3.0 23.2 5.2 1.2 2.1 1.8 4.1 3.1 2.1 1.4 1.4 1.0 4.5 9.2 1.6 2.1 0.9 2.0 57.8 1.9 3.9 1.0 4.9 4.6 0.5 9.1 1.8 0.8 1.5 32.0 2.5 1.2 7.6 18.6 1.4 0.6 2.8 16.9 1.2 6.4 2.4 3.3 9.4 4.7 16.8 6.4 4.7 1.9 1.6 2.4 0.2 0.1 0.0 3.1 14.9 3.6 10.0 4.5 8.1 5.8 2.5 0.6 1.7 1.0 7.4 2.1 5.0 4.1 9.1 1.2 0.8 4.2 0.2 0.4 25.8 3.1 1.4 21.9 1.1 7.9 8.5 7.4 0.0 1.7 8.1 3.7 1.6 5.0 4.7 0.6 2.8 5.0 0.8 9.5 4.4 1.0 0.0 1.2 1.3 0.0 0.0 2.1 3.0 5.1 3.3 18.3 4.4 2.6 0.4 0.0 10.3 5.3 1.2 4.3 2.7 16.8 1.3 6.4 0.4 1.3 1.5 1.3 4.7 9.4 0.2 1.0 0.9 4.7 5.7 2.3 1.9 1.6 1.6 3.9 10.9 2.7 2.1 1.4 1.6 2.1 1.0 0.6 GCNT2 "bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3" ENSG00000111846 "Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)" Q8N0V5 6 10492223-10629368 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.1" "Cell line enhanced" "Detected in many" "EFO-21: 26.2;Hep G2: 10.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in many" 4 "basal ganglia: 54.8" "Low region specificity" "Detected in all" HPA026776 Approved Supported "Golgi apparatus" 560000 "Golgi apparatus" "HPA026776: AB_1849573" "unprognostic (2.47e-1)" "unprognostic (6.87e-3)" "unprognostic (3.12e-1)" "unprognostic (1.42e-2)" "unprognostic (9.31e-2)" "unprognostic (2.51e-1)" "unprognostic (4.11e-2)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (6.28e-4)" "unprognostic (3.96e-2)" "unprognostic (1.58e-3)" "unprognostic (6.54e-2)" "unprognostic (6.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" 2.0 0.9 2.5 7.9 2.8 0.7 12.7 7.6 1.9 6.0 13.0 2.0 0.9 7.8 5.6 1.3 3.7 1.7 2.8 11.8 2.2 2.4 19.6 14.3 10.4 3.3 2.4 0.4 0.9 5.5 1.0 6.2 3.1 4.0 21.9 3.7 8.1 7.4 0.9 2.3 2.5 25.1 2.6 2.2 4.2 8.3 9.0 2.9 0.9 2.4 1.2 7.2 2.0 3.0 2.1 2.5 4.2 3.1 0.5 0.4 0.7 4.2 3.5 1.2 2.9 0.0 0.0 3.5 0.0 3.1 0.8 0.2 6.2 3.1 2.4 26.2 0.0 0.1 0.3 3.2 1.8 1.6 0.9 0.5 1.8 10.9 0.0 1.1 2.9 0.0 0.0 0.3 0.0 6.9 0.3 0.0 0.3 0.0 0.0 2.2 3.9 2.4 0.1 2.4 3.8 9.3 2.3 2.6 1.8 0.0 9.2 8.8 0.1 0.4 5.9 0.5 0.4 0.0 3.4 0.0 0.0 1.7 0.5 0.2 1.4 4.2 3.1 1.3 0.3 2.3 0.1 2.1 0.3 0.4 2.5 1.3 0.4 0.4 0.2 0.5 0.8 0.6 0.2 0.7 2.5 2.8 7.6 1.9 2.2 2.4 2.4 0.4 4.0 2.9 GCNT3 "C2/4GnT, C2GnT-M, C2GnT2" ENSG00000140297 "Glucosaminyl (N-acetyl) transferase 3, mucin type" O95395 15 59594875-59640239 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 29.6;intestine: 103.3;salivary gland: 27.4" "Cell line enriched" "Detected in some" 5 "A549: 55.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 29.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011154 Enhanced Approved "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA011154: AB_1078961" "unprognostic (5.09e-2)" "unprognostic (2.39e-1)" "unprognostic (5.92e-2)" "prognostic favourable (1.78e-4)" "unprognostic (3.99e-3)" "unprognostic (2.02e-2)" "prognostic unfavourable (6.49e-5)" "unprognostic (1.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.34e-1)" "unprognostic (1.64e-2)" "unprognostic (1.63e-1)" "unprognostic (4.02e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-2)" "unprognostic (4.65e-2)" "unprognostic (2.43e-1)" 0.3 0.5 0.3 8.8 0.4 0.0 0.3 0.3 0.3 5.3 37.6 0.3 0.3 25.4 1.3 0.4 8.7 0.7 29.6 0.3 0.3 0.2 9.9 0.4 0.7 0.3 0.3 0.3 1.1 1.7 0.0 0.4 1.0 0.5 1.0 33.4 0.3 27.4 0.3 0.3 0.2 103.3 0.9 0.3 0.3 6.5 1.7 0.3 0.5 0.7 5.2 15.5 0.7 14.0 1.2 1.4 3.4 0.8 1.1 0.7 0.1 0.0 55.8 0.0 0.0 0.0 0.4 0.0 0.0 2.9 0.0 0.0 2.3 2.3 0.2 9.6 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 11.2 0.0 0.1 0.1 0.1 1.3 0.2 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.2 3.9 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.1 0.1 0.2 3.5 0.1 0.0 2.6 0.8 0.6 0.7 0.4 0.4 0.6 0.5 0.3 0.2 1.2 0.4 0.6 3.4 1.1 0.4 1.4 0.5 0.1 0.3 0.4 0.3 0.3 0.3 0.2 0.3 0.3 0.5 0.3 GCNT4 C2GNT3 ENSG00000176928 "Glucosaminyl (N-acetyl) transferase 4, core 2" Q9P109 5 75025346-75030899 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 13.6;intestine: 13.1;stomach 1: 10.4" "Cell line enriched" "Detected in some" 5 "RT4: 26.3" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 13.6" "Group enriched" "Detected in many" 54 "granulocytes: 13.6;T-cells: 11.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037431 Approved Supported "Nucleoplasm,Golgi apparatus" "Golgi apparatus" Nucleoplasm "HPA037431: AB_10670382" "unprognostic (1.88e-2)" "unprognostic (5.63e-2)" "unprognostic (6.05e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-1)" "unprognostic (4.98e-2)" "unprognostic (4.11e-3)" "unprognostic (1.63e-2)" "unprognostic (3.47e-1)" "unprognostic (2.20e-2)" "unprognostic (4.49e-3)" "unprognostic (6.04e-2)" "prognostic favourable (1.93e-7)" "unprognostic (8.39e-2)" "unprognostic (1.93e-1)" "unprognostic (6.06e-2)" "unprognostic (5.82e-2)" 0.6 0.6 0.3 1.0 0.7 0.0 0.9 0.0 2.3 1.1 1.1 13.1 1.4 0.6 1.3 1.1 2.5 0.3 0.3 0.1 1.8 0.4 1.0 1.7 0.1 0.9 3.0 8.4 0.1 3.0 1.0 0.2 0.5 2.4 1.0 1.5 10.8 0.7 0.0 0.6 10.4 1.0 0.5 1.1 6.4 2.0 0.0 0.0 13.6 0.1 0.2 11.6 1.6 0.2 0.1 1.0 1.6 1.8 0.6 0.1 2.0 5.2 1.0 0.9 2.5 0.1 0.0 0.2 1.5 0.7 1.0 1.8 0.2 0.0 0.0 0.8 0.2 0.2 0.8 0.0 0.0 0.3 2.9 0.1 0.3 0.0 0.0 0.3 0.1 0.0 1.4 0.0 0.4 0.0 0.0 0.0 2.6 0.2 26.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.7 0.1 0.0 0.0 0.0 0.3 0.0 0.1 13.6 0.0 0.0 0.9 0.0 3.5 0.0 8.1 2.6 0.0 0.0 8.1 5.9 0.1 0.2 0.1 0.0 11.6 1.6 GDA ENSG00000119125 "Guanine deaminase" Q9Y2T3 9 72114595-72257193 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.8;intestine: 54.5;liver: 27.6" "Cell line enhanced" "Detected in some" "A-431: 12.7;BJ hTERT+: 9.2;EFO-21: 50.3;HeLa: 17.6;hTCEpi: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 11 "amygdala: 39.7;basal ganglia: 31.5;cerebral cortex: 63.2;hippocampal formation: 79.5;olfactory region: 28.4" "HPA019352, HPA024099, HPA030387" Enhanced Approved Nucleoplasm 1300000 Nucleoplasm "HPA019352: AB_1855593, HPA024099: AB_1855594, HPA030387: AB_10602351" "unprognostic (2.64e-2)" "unprognostic (7.10e-2)" "unprognostic (2.83e-2)" "unprognostic (2.92e-1)" "unprognostic (4.35e-2)" "unprognostic (8.45e-2)" "unprognostic (2.00e-1)" "unprognostic (5.60e-2)" "unprognostic (3.26e-1)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (5.56e-2)" "prognostic favourable (2.66e-5)" "unprognostic (2.23e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (8.30e-4)" 0.5 1.7 26.7 1.8 27.7 0.5 0.5 0.4 33.8 1.0 20.6 0.9 7.7 47.4 2.4 0.6 0.5 4.7 13.1 0.5 25.7 15.0 21.4 27.6 0.5 0.5 2.9 27.4 0.4 1.7 10.8 1.7 10.3 0.8 0.4 5.5 0.0 0.4 4.1 1.1 1.6 54.5 0.5 0.6 0.5 2.0 1.0 0.2 0.0 0.4 1.0 2.6 3.4 0.5 1.4 0.5 3.0 0.7 1.0 1.0 0.1 12.7 1.6 0.0 0.0 0.0 0.0 0.3 0.0 9.2 0.0 0.0 1.1 7.1 0.0 50.3 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.2 0.0 3.4 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 2.9 0.0 0.2 0.9 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 3.0 0.7 0.3 1.0 0.6 0.3 0.6 0.5 0.4 0.3 1.4 0.7 0.7 1.9 1.0 0.4 0.5 0.5 0.1 26.7 27.7 0.4 33.8 25.7 15.0 2.9 27.4 0.8 0.2 GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501689-19522145 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074747 Approved Nucleoplasm,Nucleoli,Vesicles Nucleoli "Nucleoplasm, Vesicles" "HPA074747: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favourable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavourable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favourable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" 20.3 18.5 30.6 11.7 34.3 17.5 23.9 13.5 32.2 18.1 31.0 24.5 23.0 22.7 15.0 22.6 19.0 13.4 17.5 40.7 31.1 17.5 21.1 21.3 22.1 13.1 29.2 20.6 9.9 28.3 35.3 13.9 15.5 20.8 21.4 32.5 12.5 20.4 24.9 42.4 18.5 20.8 27.2 25.3 10.1 22.8 14.8 23.8 9.6 17.9 21.7 12.7 22.8 12.4 4.6 7.4 23.9 12.4 3.7 7.4 4.6 14.6 17.6 9.7 11.5 46.8 17.4 13.9 15.1 26.0 11.8 14.7 10.0 26.2 11.0 19.5 22.0 12.7 13.5 17.8 14.4 11.9 20.8 9.2 17.3 21.6 28.4 12.1 8.6 18.3 28.9 12.6 14.8 15.8 5.1 11.4 12.8 26.4 10.5 11.2 11.3 13.7 15.2 17.8 15.9 29.2 22.5 11.3 10.3 14.7 17.6 13.9 18.0 14.5 16.6 10.0 9.0 13.2 9.2 10.7 10.1 7.6 15.4 18.0 8.9 23.9 11.8 6.4 5.7 10.5 7.3 4.6 6.8 6.6 7.4 3.7 3.6 5.7 19.8 3.7 12.4 4.6 7.4 4.6 30.6 34.3 13.5 32.2 31.1 17.5 29.2 20.6 20.8 23.8 GDPGP1 C15orf58 ENSG00000183208 "GDP-D-glucose phosphorylase 1" Q6ZNW5 15 90233808-90245811 "Enzymes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Hydrolase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA048189, HPA059841" Approved Approved Cytosol Cytosol "HPA048189: , HPA059841: " "prognostic favourable (6.32e-4)" "unprognostic (1.85e-1)" "unprognostic (2.17e-1)" "unprognostic (2.42e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (2.58e-1)" "unprognostic (3.68e-2)" "unprognostic (4.46e-3)" "unprognostic (1.53e-1)" "unprognostic (3.00e-1)" "unprognostic (1.82e-2)" "unprognostic (2.93e-3)" "unprognostic (8.43e-2)" "unprognostic (1.87e-1)" "unprognostic (1.02e-3)" 3.9 9.2 9.8 5.7 9.8 5.1 4.8 9.9 12.4 4.4 10.7 8.0 7.2 10.1 5.0 7.5 6.2 9.4 6.0 10.8 12.9 7.1 7.7 12.2 5.8 6.1 5.9 11.6 6.1 9.1 11.9 10.2 2.1 8.8 7.5 14.8 7.2 9.9 10.0 12.5 4.5 9.4 5.8 5.1 8.2 6.9 9.5 8.4 8.5 7.6 3.1 7.8 7.2 3.9 8.3 4.6 7.4 5.2 6.7 7.8 2.9 3.2 13.0 1.6 4.8 4.9 1.0 4.4 3.0 1.9 4.0 3.8 3.8 12.9 8.0 5.9 2.3 5.4 5.1 3.4 1.6 7.2 8.6 7.2 7.5 5.5 5.3 3.9 4.8 1.3 2.4 2.8 1.4 4.6 2.6 3.2 2.3 7.3 2.9 1.9 2.0 5.4 5.1 1.2 4.0 4.6 6.4 5.1 2.2 4.7 7.4 5.0 8.5 4.0 4.6 2.1 2.2 3.0 2.9 6.6 7.5 3.6 4.6 3.3 3.8 6.8 4.6 2.2 6.6 5.2 5.6 4.8 6.2 7.8 4.1 8.3 6.7 6.2 7.4 6.7 4.1 4.6 7.5 2.9 9.8 9.8 9.9 12.4 12.9 7.1 5.9 11.6 8.8 8.4 GFER "ALR, ERV1, HERV1, HPO1, HPO2, HSS" ENSG00000127554 "Growth factor, augmenter of liver regeneration" P55789 16 1984207-1987749 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Growth factor, Oxidoreductase" "Cataract, Deafness, Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041227, HPA063553" Approved Enhanced Mitochondria,Cytosol "Intracellular and membrane" "Mitochondria, Cytosol" "HPA041227: AB_10795538, HPA063553: " "unprognostic (5.35e-2)" "unprognostic (2.11e-2)" "unprognostic (3.08e-1)" "unprognostic (4.42e-2)" "unprognostic (3.15e-1)" "unprognostic (2.63e-1)" "unprognostic (1.27e-2)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.56e-1)" "unprognostic (5.93e-2)" "prognostic favourable (4.06e-4)" "unprognostic (4.93e-2)" "unprognostic (3.64e-1)" "unprognostic (3.56e-1)" "unprognostic (1.09e-2)" 9.7 12.2 9.7 15.2 9.9 10.7 14.8 15.2 12.5 8.1 24.8 10.8 15.2 29.6 10.1 10.2 11.0 10.2 16.1 17.8 9.8 9.7 13.7 33.5 17.1 18.1 10.7 9.7 9.4 43.8 19.2 10.9 18.0 8.0 11.9 18.0 10.5 22.5 12.5 27.5 8.3 33.2 9.2 9.6 15.2 12.8 20.0 7.8 7.7 15.1 15.0 11.4 12.4 17.1 16.1 9.1 9.8 12.7 7.8 17.7 7.7 11.3 18.1 14.9 12.1 6.3 12.6 19.3 13.2 12.9 18.6 15.2 26.0 19.0 6.4 18.0 9.8 17.1 11.3 17.4 11.8 19.7 23.1 8.8 17.8 29.5 11.4 12.7 16.6 8.1 13.5 16.2 14.6 8.7 13.7 21.4 13.5 26.7 14.5 13.8 23.8 18.1 31.8 11.4 20.7 18.9 8.9 13.1 12.5 17.8 38.0 14.1 18.1 13.6 8.1 18.1 20.2 10.1 22.6 36.3 19.6 18.3 6.0 8.7 15.2 3.1 12.6 9.8 9.2 10.5 9.9 16.1 12.6 15.6 9.1 13.4 11.5 7.9 1.1 7.8 12.7 4.0 17.7 7.7 9.7 9.9 15.2 12.5 9.8 9.7 10.7 9.7 8.0 7.8 GFPT1 "GFA, GFAT, GFAT1, GFPT" ENSG00000198380 "Glutamine--fructose-6-phosphate transaminase 1" Q06210 2 69319769-69387254 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Aminotransferase, Transferase" "Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047240 Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA047240: " "unprognostic (4.38e-3)" "unprognostic (8.20e-2)" "prognostic favourable (7.13e-5)" "unprognostic (2.97e-1)" "unprognostic (1.32e-1)" "unprognostic (2.40e-2)" "unprognostic (1.08e-2)" "unprognostic (2.11e-1)" "unprognostic (2.99e-1)" "unprognostic (3.14e-1)" "unprognostic (4.84e-2)" "unprognostic (5.00e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.78e-1)" "unprognostic (1.63e-1)" "unprognostic (2.58e-1)" 16.7 11.4 6.4 12.7 7.8 5.6 18.3 7.8 10.1 16.8 27.0 6.4 41.2 14.5 10.1 18.7 11.6 9.5 19.4 11.3 6.0 9.8 17.8 49.1 14.1 4.7 6.5 5.7 11.1 34.9 13.9 39.6 36.5 7.0 17.2 27.5 7.7 39.7 34.0 9.2 6.1 28.2 8.7 6.2 8.2 24.6 13.9 4.8 8.5 35.2 7.7 18.1 10.6 16.2 5.6 4.1 5.9 3.4 4.1 6.8 3.0 9.5 6.6 8.5 5.3 24.0 16.5 18.5 18.2 17.0 8.6 11.0 21.2 8.7 8.6 6.7 16.9 4.6 10.7 5.6 14.3 7.8 4.1 10.0 4.9 21.8 28.4 6.8 4.0 10.4 27.3 16.7 32.0 8.0 8.3 14.0 16.8 5.6 7.2 7.1 11.1 5.5 7.2 17.8 4.4 14.0 7.6 5.3 3.0 6.8 12.6 24.4 5.0 4.3 12.2 7.7 10.3 13.2 8.7 10.0 6.7 6.5 12.5 4.6 8.8 5.9 2.8 3.4 6.8 3.2 6.5 5.6 6.1 6.6 3.6 3.4 6.1 5.6 1.3 4.1 3.4 4.1 4.3 3.0 6.4 7.8 7.8 10.1 6.0 9.8 6.5 5.7 7.0 4.8 GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300690-180353387 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 65.6" "Cell line enhanced" "Detected in many" "ASC diff: 24.0;ASC TERT1: 41.2;HSkMC: 26.4;hTEC/SVTERT24-B: 49.0;U-87 MG: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "MAIT T-cell: 7.1" "Lineage enriched" "Detected in single" 49 "T-cells: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Supported Vesicles Vesicles "HPA056892: , HPA059910: " "unprognostic (3.48e-1)" "prognostic unfavourable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavourable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavourable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavourable (3.47e-4)" "unprognostic (1.52e-3)" 65.6 3.9 4.5 15.8 5.6 0.9 11.0 17.0 9.2 10.0 9.2 9.3 5.4 2.1 9.0 16.7 5.9 15.9 14.6 16.4 7.1 3.8 2.8 2.6 11.0 3.1 6.2 6.8 17.5 11.1 3.5 2.5 6.0 8.4 7.7 3.6 2.9 4.0 8.0 6.0 4.0 5.0 10.0 17.2 1.7 6.6 6.3 7.7 0.0 5.6 5.4 3.5 14.3 14.6 0.0 0.1 0.0 0.0 0.1 7.1 0.2 0.0 5.3 4.2 5.4 24.0 41.2 0.4 0.6 0.1 0.4 0.1 0.1 0.0 0.0 0.2 4.4 0.0 2.3 0.0 0.2 0.5 0.8 0.0 2.6 0.0 10.0 0.0 0.0 26.4 0.2 49.0 0.1 7.9 0.0 0.0 21.0 0.7 0.0 0.0 9.0 2.4 0.1 0.0 0.0 0.0 0.0 0.2 0.3 8.3 0.1 0.3 0.3 0.0 3.7 13.5 2.1 8.7 9.9 0.0 0.0 0.0 85.2 0.0 0.3 0.0 0.0 0.0 1.4 0.0 7.1 0.0 0.8 2.4 0.1 0.0 0.8 1.1 0.0 0.1 0.0 0.1 0.0 0.2 4.5 5.6 17.0 9.2 7.1 3.8 6.2 6.8 8.4 7.7 GGACT A2LD1 ENSG00000134864 "Gamma-glutamylamine cyclotransferase" Q9BVM4 13 100530164-100589528 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 47.0" "Cell line enriched" "Detected in many" 5 "SCLC-21H: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065320 Enhanced 75000 "HPA065320: " "unprognostic (1.93e-1)" "unprognostic (5.33e-2)" "unprognostic (2.32e-1)" "unprognostic (1.30e-3)" "unprognostic (9.12e-3)" "unprognostic (1.64e-2)" "unprognostic (1.58e-2)" "unprognostic (2.07e-2)" "unprognostic (7.41e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-2)" "unprognostic (2.45e-1)" "unprognostic (1.95e-2)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" "unprognostic (3.37e-2)" "unprognostic (2.57e-1)" 3.6 6.6 3.2 3.4 3.4 0.9 3.4 2.6 4.5 2.0 4.9 3.6 1.7 5.7 4.0 3.4 2.8 2.5 5.5 1.7 2.6 2.2 47.0 10.9 2.4 4.6 3.5 2.1 2.5 9.8 1.8 1.9 2.1 4.4 2.4 3.4 4.1 12.0 14.2 2.7 3.1 6.7 3.4 4.3 6.1 4.4 11.0 3.3 3.7 2.5 5.0 6.4 2.5 2.5 5.2 4.2 1.0 7.5 8.0 8.3 4.2 5.5 0.7 4.5 4.9 3.9 6.0 1.9 3.5 0.9 0.6 1.5 0.0 5.0 0.5 2.0 2.5 0.3 0.7 1.0 0.2 7.7 3.0 2.3 0.4 0.2 5.5 3.3 7.7 7.1 4.0 0.1 0.3 2.3 1.1 0.1 0.9 0.3 0.5 0.4 0.2 1.5 0.3 1.1 0.6 5.6 0.9 54.1 2.0 1.1 2.5 2.5 2.3 11.0 2.1 0.0 0.0 1.2 0.9 2.9 1.6 0.2 0.3 2.5 2.5 0.0 5.1 1.0 7.9 7.2 7.3 5.2 6.4 8.3 4.2 5.0 4.0 5.9 0.0 8.0 7.5 3.0 6.5 4.2 3.2 3.4 2.6 4.5 2.6 2.2 3.5 2.1 4.4 3.3 GGCT "C7orf24, CRF21, GCTG, Ggc, MGC3077" ENSG00000006625 Gamma-glutamylcyclotransferase O75223 7 30496621-30504844 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA020735, HPA029914" Approved 2400000 "HPA020735: AB_1845754, HPA029914: AB_10602321" "prognostic unfavourable (7.68e-4)" "unprognostic (2.66e-1)" "unprognostic (2.51e-2)" "unprognostic (2.62e-1)" "unprognostic (2.54e-3)" "unprognostic (5.80e-2)" "prognostic unfavourable (7.23e-4)" "unprognostic (1.33e-3)" "unprognostic (2.19e-2)" "unprognostic (6.42e-3)" "unprognostic (2.66e-3)" "unprognostic (1.68e-1)" "unprognostic (2.27e-2)" "unprognostic (1.19e-1)" "unprognostic (8.12e-3)" "unprognostic (2.00e-3)" "unprognostic (9.92e-2)" 30.8 18.6 15.5 14.5 15.9 10.2 26.4 10.8 25.6 12.6 20.2 7.3 19.3 16.7 10.4 59.6 33.4 13.5 22.5 12.2 14.6 12.4 22.0 18.7 14.6 13.6 11.6 14.4 15.2 17.2 14.9 11.4 18.5 15.0 14.3 21.9 8.0 23.9 19.2 12.6 29.8 16.8 14.2 9.9 13.2 13.3 8.1 5.8 11.0 28.7 32.1 18.9 17.4 19.1 14.8 21.7 5.6 12.8 15.3 16.4 10.1 40.2 10.6 17.2 23.2 7.3 13.3 20.1 13.8 5.4 13.3 16.1 14.0 14.1 26.0 9.1 5.1 51.4 18.1 14.4 17.4 4.9 20.0 18.4 21.4 18.4 9.5 30.9 14.3 12.9 11.6 13.8 17.9 13.4 26.1 15.0 10.4 22.2 18.7 41.8 24.9 17.1 18.8 20.0 25.9 12.7 36.8 21.9 22.1 12.3 77.4 14.7 49.6 29.3 8.0 8.7 16.4 16.5 26.8 11.1 26.1 20.1 6.8 42.0 16.2 5.6 12.8 4.2 9.6 12.5 13.3 14.8 12.7 12.3 21.7 11.7 12.3 11.9 0.7 15.3 7.3 19.1 16.4 10.1 15.5 15.9 10.8 25.6 14.6 12.4 11.6 14.4 15.0 5.8 GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544723-85561547 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" Lyase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 74.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Approved "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavourable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" 7.1 7.8 4.8 4.2 6.3 1.6 10.8 6.3 6.6 6.4 4.9 5.4 8.3 4.0 6.3 8.1 6.5 5.9 7.0 6.8 5.4 3.6 9.0 74.8 8.1 5.4 5.4 5.0 7.0 11.4 15.1 5.6 13.8 5.9 6.3 5.5 5.8 7.4 7.9 6.8 4.9 5.5 7.2 5.1 4.5 6.0 3.6 5.7 3.4 8.5 5.3 5.4 7.3 6.0 0.9 4.9 6.0 7.2 2.2 3.2 3.2 6.8 11.1 7.9 8.8 40.0 11.4 17.6 12.2 14.4 9.0 12.8 19.0 8.4 2.4 12.5 20.0 11.1 5.6 15.4 10.0 4.3 7.7 4.4 7.4 18.0 14.9 2.7 4.2 14.1 9.1 18.2 12.5 12.7 5.3 3.6 26.1 8.9 1.4 2.1 3.7 9.6 2.6 18.6 6.1 12.5 13.1 3.0 5.0 10.9 21.6 11.3 10.5 2.7 11.6 11.6 10.2 11.2 8.3 2.8 7.8 2.0 11.1 2.8 16.2 6.0 7.2 3.6 3.2 7.2 3.0 0.7 1.3 1.2 4.9 0.9 3.2 3.0 3.2 2.2 4.4 4.0 1.9 3.2 4.8 6.3 6.3 6.6 5.4 3.6 5.4 5.0 5.9 5.7 GGH ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63015079-63039171 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 42.5;liver: 59.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 18.2" "Lineage enriched" "Detected in all" 4 "dendritic cells: 18.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved "Intracellular and membrane" 1400000000 "CAB019296: , HPA025226: AB_1849645" "unprognostic (9.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.48e-3)" "prognostic unfavourable (3.99e-7)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavourable (1.65e-4)" "unprognostic (1.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-2)" "unprognostic (9.62e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" 3.5 3.6 7.4 4.7 8.6 12.3 11.8 15.5 9.9 3.5 17.6 1.5 1.0 3.7 2.6 3.7 11.0 1.6 2.8 5.9 7.9 7.6 42.5 59.5 3.5 5.0 4.7 7.0 1.9 4.2 1.0 1.6 17.7 14.8 1.9 26.4 2.2 6.5 1.8 1.7 11.1 3.6 4.2 7.6 3.7 3.2 14.0 3.8 5.2 1.4 14.5 7.6 3.9 6.6 4.1 18.2 2.1 1.9 2.9 1.4 1.4 20.4 19.7 20.2 3.1 19.9 8.4 14.9 12.6 21.6 20.0 29.1 27.5 36.3 14.0 3.6 15.6 17.1 20.0 21.1 29.8 28.4 15.1 23.0 10.6 18.6 3.8 10.7 13.8 6.1 6.0 20.2 9.7 24.2 12.2 51.3 37.5 11.6 5.2 10.7 9.5 18.6 15.6 19.7 18.8 15.5 7.2 8.1 13.8 18.4 20.1 19.1 22.2 11.9 12.8 21.6 24.2 20.7 22.7 24.0 24.4 16.4 33.4 0.0 38.1 0.0 1.9 2.1 1.1 1.1 0.5 4.1 1.3 1.3 0.6 1.9 1.0 1.3 1.8 2.9 1.2 18.2 1.4 1.4 7.4 8.6 15.5 9.9 7.9 7.6 4.7 7.0 14.8 3.8 GGPS1 GGPPS1 ENSG00000152904 "Geranylgeranyl diphosphate synthase 1" O95749 1 235327350-235344532 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Isoprene biosynthesis" Transferase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029472 Enhanced "HPA029472: AB_10696206" "unprognostic (7.45e-2)" "unprognostic (3.18e-2)" "unprognostic (1.25e-1)" "unprognostic (2.23e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-3)" "prognostic unfavourable (6.69e-4)" "unprognostic (4.50e-2)" "unprognostic (3.66e-2)" "unprognostic (3.77e-3)" "unprognostic (2.66e-2)" "unprognostic (8.77e-3)" "unprognostic (1.95e-2)" "unprognostic (1.99e-1)" "unprognostic (3.35e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-2)" 24.5 24.8 26.8 16.2 25.7 6.8 33.4 30.1 28.7 24.9 23.1 19.9 21.8 19.8 22.8 30.3 24.1 20.9 19.2 21.8 25.4 25.8 26.4 20.0 18.9 18.3 24.4 22.0 23.5 16.0 19.0 29.3 24.2 25.8 29.0 23.2 15.9 27.8 21.9 26.8 19.0 20.6 24.9 28.3 20.4 20.1 42.5 25.6 22.6 27.9 21.2 20.0 26.9 17.9 28.5 22.2 33.9 35.9 22.1 31.3 26.0 17.6 9.6 24.0 18.1 18.7 27.1 9.4 15.7 22.0 10.4 14.7 7.4 28.2 12.0 22.9 17.3 14.4 12.7 16.2 13.8 12.1 23.7 10.1 9.1 12.5 21.1 12.4 8.7 17.6 29.3 14.1 19.1 18.4 24.2 10.8 13.7 10.3 15.5 14.9 20.5 5.0 9.6 7.5 13.6 29.0 9.6 19.3 26.7 11.8 27.1 22.6 33.8 19.9 15.5 12.5 9.4 21.1 14.7 18.9 22.8 14.6 15.8 14.1 22.4 26.6 22.8 33.9 24.8 26.8 24.9 28.5 31.3 26.4 22.2 23.4 29.2 26.5 20.6 22.1 35.9 18.4 30.0 26.0 26.8 25.7 30.1 28.7 25.4 25.8 24.4 22.0 25.8 25.6 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24583750-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 54.1;seminal vesicle: 41.7" "Cell line enhanced" "Detected in many" "HDLM-2: 35.8;Karpas-707: 52.7;RPMI-8226: 51.8;RPTEC TERT1: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA045635, HPA047534, HPA065444" Supported Approved Vesicles "Intracellular and membrane" 4600000 Vesicles "HPA045635: , HPA047534: , HPA065444: " "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favourable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favourable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 1.6 0.5 1.7 1.7 2.2 2.7 8.2 2.3 2.6 7.3 7.9 1.6 23.7 22.3 1.4 19.9 1.2 0.8 12.2 2.0 1.8 1.2 54.1 29.2 14.3 3.2 1.7 1.6 1.3 17.3 0.0 1.6 1.4 2.2 14.7 2.4 1.4 8.7 41.7 0.9 1.1 20.9 1.7 1.9 4.7 6.6 5.0 2.1 2.4 4.8 1.6 5.5 2.1 1.1 3.3 7.5 15.9 14.6 6.6 8.6 6.6 0.2 19.4 0.2 0.0 0.0 0.1 0.5 0.1 0.6 0.2 0.2 2.6 4.3 0.2 4.3 0.0 2.8 1.4 0.2 0.1 35.8 2.9 0.1 8.6 14.1 1.5 0.3 12.0 0.4 0.2 0.6 0.4 0.1 2.0 52.7 0.2 0.4 0.3 14.6 1.4 0.2 0.2 2.2 51.8 48.2 0.6 0.2 0.3 0.1 9.4 0.2 9.4 11.1 2.2 3.5 2.3 10.9 0.3 15.8 6.0 0.2 7.4 15.1 0.1 5.2 14.6 0.4 1.4 6.8 5.2 3.3 7.7 3.4 7.5 0.3 1.0 1.9 15.9 6.6 5.5 0.1 8.6 6.6 1.7 2.2 2.3 2.6 1.8 1.2 1.7 1.6 2.2 2.1 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245142 "Enzymes, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "ASC diff: 38.7;ASC TERT1: 29.4;HHSteC: 55.2;HSkMC: 63.6;TIME: 24.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 4.0;eosinophil: 7.5;neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" 18000000 "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavourable (6.36e-5)" "prognostic unfavourable (4.06e-4)" "prognostic unfavourable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 20.2 14.8 2.0 5.2 3.5 0.0 13.2 0.5 4.2 10.7 4.0 5.7 7.9 3.6 2.1 10.2 12.1 14.0 2.4 3.4 13.1 13.7 5.1 12.4 4.7 3.9 5.0 2.2 6.0 3.2 6.5 3.4 5.4 6.8 2.5 5.3 7.2 10.1 2.7 4.8 5.6 1.2 17.2 5.2 6.3 9.3 0.1 0.4 7.5 0.9 0.8 0.1 0.4 0.0 0.3 0.0 0.0 38.7 29.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.1 5.0 55.2 0.6 1.3 63.6 0.0 0.7 0.7 10.3 0.1 0.1 9.9 0.1 0.0 4.8 0.6 0.0 0.0 0.9 0.1 1.1 0.0 0.0 1.3 0.0 1.6 0.0 0.2 0.3 24.7 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.1 0.0 4.0 0.9 7.5 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.9 0.8 0.0 0.1 0.0 0.4 GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.4;salivary gland: 52.7" "Group enriched" "Detected in some" 8 "RT4: 29.8;SK-BR-3: 10.2;T-47d: 31.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved 33000 "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favourable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favourable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" 0.3 0.4 0.3 12.7 0.3 0.0 3.2 0.3 0.4 4.1 24.9 0.4 1.0 17.0 0.9 15.9 25.2 3.0 7.7 0.3 0.3 0.1 18.8 0.6 4.2 0.3 0.3 0.3 1.5 28.6 0.0 1.0 0.4 0.4 5.7 12.7 0.4 52.7 3.7 0.3 25.2 40.4 2.8 0.3 0.3 8.7 0.8 0.3 1.0 0.7 19.6 18.8 16.5 8.2 0.6 0.7 3.5 0.5 0.6 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 29.8 0.1 0.1 0.0 10.2 0.0 31.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.5 0.2 0.4 0.3 0.2 0.3 0.5 0.3 0.1 0.6 0.5 0.4 1.9 0.6 0.5 0.7 0.4 0.0 0.3 0.3 0.3 0.4 0.3 0.1 0.3 0.3 0.4 0.3 GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872860 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles 1500000 Vesicles Nucleoplasm "HPA013204: AB_1850347, HPA013339: " "unprognostic (1.32e-3)" "unprognostic (2.33e-1)" "unprognostic (9.31e-2)" "prognostic unfavourable (1.26e-5)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-3)" "unprognostic (2.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-2)" "unprognostic (3.34e-3)" "unprognostic (3.61e-2)" "unprognostic (5.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-1)" "unprognostic (5.50e-2)" "unprognostic (2.00e-1)" 6.8 6.7 21.6 6.7 23.7 2.9 8.5 42.6 29.1 9.5 11.5 9.7 14.3 9.8 12.3 19.5 6.4 10.5 11.4 13.8 19.7 17.0 9.9 7.2 9.0 10.3 11.2 32.1 13.4 19.5 20.8 18.3 8.5 19.2 11.4 9.6 6.9 18.8 15.3 31.6 11.1 9.0 9.6 11.0 8.3 12.9 5.0 15.6 4.9 16.3 4.3 8.2 9.3 8.5 6.1 2.6 1.5 3.0 3.2 12.8 1.8 2.2 3.3 17.0 17.4 13.4 12.0 15.1 9.4 9.6 7.8 11.6 17.4 11.1 0.0 11.2 7.3 1.5 7.3 4.1 5.1 0.7 13.1 6.7 5.9 9.1 12.0 0.3 11.1 17.4 4.7 8.7 4.0 0.6 5.0 1.2 5.3 3.8 1.7 3.4 3.9 1.7 0.0 11.6 10.7 11.3 3.3 9.9 11.6 4.8 7.7 12.1 5.9 6.1 0.2 26.8 10.7 2.5 5.3 13.1 1.7 0.8 31.5 0.6 9.8 1.5 3.0 1.4 7.4 2.0 2.1 5.6 6.3 2.8 2.6 6.1 12.8 8.9 0.3 3.2 0.7 1.4 4.8 1.8 21.6 23.7 42.6 29.1 19.7 17.0 11.2 32.1 19.2 15.6 GK "GK1, GKD" ENSG00000198814 "Glycerol kinase" P32189 X 30653359-30731456 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 51.4;intestine: 37.9;kidney: 35.4;liver: 40.7" "Cell line enhanced" "Detected in many" "Hep G2: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "neutrophil: 51.4" "Lineage enriched" "Detected in all" 8 "granulocytes: 51.4" HPA060687 Supported "HPA060687: " "unprognostic (8.78e-3)" "unprognostic (8.41e-3)" "unprognostic (1.28e-2)" "unprognostic (3.77e-2)" "unprognostic (3.15e-1)" "unprognostic (4.15e-3)" "unprognostic (5.52e-2)" "unprognostic (1.42e-2)" "unprognostic (3.85e-1)" "unprognostic (8.56e-3)" "unprognostic (1.30e-2)" "unprognostic (1.58e-2)" "prognostic favourable (3.24e-9)" "unprognostic (1.59e-1)" "unprognostic (9.35e-2)" "unprognostic (4.57e-3)" "unprognostic (4.11e-3)" 2.8 4.9 2.4 17.0 7.6 1.6 1.8 2.5 4.7 3.0 7.5 2.7 1.5 28.4 2.5 4.0 4.9 2.7 7.9 4.9 4.6 2.6 35.4 40.7 11.7 8.1 3.8 2.5 2.0 1.9 3.2 5.3 2.3 4.1 1.9 3.4 2.9 6.6 0.6 1.4 3.1 37.9 1.9 6.0 6.4 2.0 2.0 2.2 5.4 2.2 3.8 4.5 4.3 1.7 1.7 4.0 51.4 6.6 1.2 3.2 1.6 2.5 2.0 2.7 4.7 1.7 6.4 1.1 6.2 22.1 4.6 5.2 3.3 2.4 7.4 1.0 2.4 0.1 5.0 2.0 6.1 4.7 5.6 4.3 4.2 26.8 10.6 8.0 9.4 3.9 3.1 14.5 13.8 3.6 2.3 10.5 1.2 3.7 6.2 8.6 4.5 2.4 8.6 4.2 7.6 3.4 8.7 2.9 3.6 5.5 5.6 12.3 6.4 5.8 1.4 3.3 1.4 0.1 2.8 5.5 5.9 7.2 5.8 5.3 3.3 1.3 6.6 2.2 0.5 2.0 0.4 0.8 0.9 0.6 4.0 1.7 0.5 0.6 51.4 1.2 2.4 1.2 3.2 1.6 2.4 7.6 2.5 4.7 4.6 2.6 3.8 2.5 4.1 2.2 GK2 "GKP2, GKTA" ENSG00000196475 "Glycerol kinase 2" Q14410 4 79406352-79408293 "Enzymes, Plasma proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 90 "testis: 61.0" "Cell line enriched" "Detected in single" 52 "SCLC-21H: 9.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 2.0" HPA060687 Uncertain "HPA060687: " "unprognostic (1.31e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GK3P "GKP3, GKTB" ENSG00000229894 "Glycerol kinase 3 pseudogene" Q14409 4 165277812-165279679 "Enzymes, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 17.0" "Cell line enhanced" "Detected in single" "TIME: 1.0" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 12 "neutrophil: 2.9" "Lineage enriched" "Detected in single" 12 "granulocytes: 2.9" HPA060687 Uncertain "HPA060687: " "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.17e-2)" "unprognostic (2.11e-2)" "unprognostic (3.94e-1)" "unprognostic (1.61e-1)" "unprognostic (2.04e-1)" "unprognostic (6.19e-2)" "unprognostic (6.99e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (4.56e-1)" "unprognostic (3.34e-4)" 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.1 2.9 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.2 1.0 0.0 0.1 0.0 0.1 0.0 0.4 0.8 0.0 0.0 0.7 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.9 0.0 0.1 0.0 0.1 0.0 GK5 MGC40579 ENSG00000175066 "Glycerol kinase 5 (putative)" Q6ZS86 3 142157527-142225607 "Enzymes, Predicted intracellular proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042606, HPA057998" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA042606: AB_10795509, HPA057998: " "unprognostic (7.79e-2)" "unprognostic (5.15e-2)" "unprognostic (2.02e-2)" "unprognostic (1.33e-1)" "unprognostic (3.07e-2)" "unprognostic (3.60e-2)" "unprognostic (9.89e-3)" "unprognostic (3.13e-1)" "unprognostic (2.77e-2)" "unprognostic (1.76e-2)" "unprognostic (7.76e-2)" "unprognostic (2.03e-1)" "unprognostic (1.12e-2)" "unprognostic (2.10e-3)" "unprognostic (4.49e-2)" "unprognostic (1.32e-1)" "unprognostic (5.59e-3)" 6.1 12.2 5.6 5.7 7.2 10.8 10.9 9.0 9.4 11.5 10.9 8.4 11.5 14.4 10.9 14.8 7.9 7.2 8.3 5.4 5.5 4.1 5.7 3.1 6.2 3.5 9.3 6.0 11.5 4.8 5.4 20.3 3.7 12.6 13.5 11.8 6.7 14.8 14.7 5.0 8.8 14.0 9.4 11.6 3.5 8.1 6.2 5.3 4.6 7.4 4.2 6.1 8.5 6.7 1.3 1.1 3.6 5.3 3.8 3.8 0.5 10.9 2.7 4.0 2.7 8.3 15.8 6.9 3.6 2.5 4.0 2.5 4.2 6.1 7.9 3.3 3.5 4.7 4.5 3.5 5.3 2.8 4.4 5.1 6.6 3.1 4.5 5.8 6.9 6.5 3.1 2.6 3.5 2.3 4.5 4.8 7.3 7.0 5.1 4.9 2.6 3.2 4.9 4.2 2.9 4.2 6.9 3.9 2.9 10.1 10.7 3.2 14.9 3.9 2.5 3.2 2.7 7.0 4.0 5.1 4.8 8.1 5.8 3.7 5.4 3.6 1.1 0.7 3.8 0.9 1.9 0.5 1.3 1.4 0.8 1.3 1.0 1.7 3.2 3.8 5.3 1.1 0.6 0.5 5.6 7.2 9.0 9.4 5.5 4.1 9.3 6.0 12.6 5.3 GLA GALA ENSG00000102393 "Galactosidase alpha" P06280 X 101397803-101407925 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000237, HPA000966" Enhanced "Intracellular and membrane" 910000 "HPA000237: AB_1078968, HPA000966: AB_1078969" "unprognostic (7.27e-3)" "unprognostic (1.47e-2)" "unprognostic (1.57e-2)" "unprognostic (2.94e-1)" "unprognostic (1.60e-1)" "unprognostic (3.15e-2)" "prognostic unfavourable (5.62e-5)" "unprognostic (2.53e-1)" "unprognostic (3.42e-1)" "unprognostic (1.89e-1)" "unprognostic (2.97e-2)" "unprognostic (3.27e-2)" "unprognostic (2.73e-2)" "prognostic favourable (6.16e-4)" "unprognostic (1.13e-1)" "unprognostic (5.44e-2)" "unprognostic (2.21e-1)" 21.1 22.2 5.2 10.0 6.3 15.6 19.2 6.2 5.7 10.8 12.7 7.3 23.2 14.8 11.7 14.1 9.4 11.5 9.1 10.5 5.2 6.3 28.7 18.9 18.7 12.0 9.4 3.2 9.7 8.3 9.8 10.5 17.9 8.6 8.3 11.2 9.4 9.5 47.7 5.9 8.9 21.3 10.8 11.9 20.8 8.5 4.9 5.8 10.2 8.3 13.4 11.2 12.2 8.9 5.4 15.9 12.8 20.9 3.0 6.1 10.1 7.2 28.4 8.2 8.4 19.0 7.4 3.7 8.3 13.0 15.8 45.2 15.4 11.2 8.0 17.7 8.5 17.3 16.1 9.0 13.7 4.9 11.9 4.4 23.6 18.1 4.9 6.1 81.0 6.5 2.9 18.2 5.3 12.8 6.8 17.7 15.1 12.9 6.1 12.7 12.0 11.5 4.4 10.1 19.5 23.2 14.7 3.0 5.1 19.3 8.2 7.7 3.8 12.6 7.3 5.5 6.6 13.1 6.7 5.4 6.2 6.1 9.5 10.2 6.1 9.5 20.8 6.2 4.6 20.9 6.1 5.4 3.7 5.7 15.9 4.9 3.8 4.7 12.8 3.0 20.8 6.7 4.3 10.1 5.2 6.3 6.2 5.7 5.2 6.3 9.4 3.2 8.6 5.8 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996608-33097230 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" 1700000 Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: , HPA069503: " "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favourable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 17.3 33.1 9.6 14.9 14.7 9.5 18.4 8.9 19.8 18.3 21.9 12.1 19.8 21.2 18.3 55.0 12.7 15.2 25.8 13.7 9.7 10.0 35.0 33.2 24.3 25.0 9.2 9.7 18.3 25.3 28.4 16.4 26.5 14.0 13.6 23.7 23.5 21.1 17.7 6.1 12.9 28.3 15.6 9.8 21.4 22.7 10.0 8.0 8.3 26.9 7.7 19.5 18.4 13.6 11.1 45.2 22.7 39.2 6.8 20.9 20.9 5.6 9.8 6.3 7.6 39.1 20.3 136.7 9.1 24.7 11.7 15.1 13.9 13.6 2.8 8.1 18.6 5.5 6.0 11.6 8.7 16.0 5.0 10.9 5.9 7.1 20.1 7.6 11.2 23.4 11.2 10.6 6.3 18.0 9.8 10.6 12.8 6.6 4.5 5.0 4.3 4.3 3.9 4.2 13.0 12.6 8.4 1.9 6.6 11.7 19.0 11.4 12.6 19.9 10.5 7.5 5.2 10.3 7.7 8.4 13.4 0.9 15.9 11.0 5.7 10.5 39.2 22.7 8.3 34.6 11.8 11.1 10.2 9.1 45.2 10.0 5.4 6.5 15.5 6.8 23.7 9.5 20.9 20.9 9.6 14.7 8.9 19.8 9.7 10.0 9.2 9.7 14.0 8.0 GLCE "HSEPI, KIAA0836" ENSG00000138604 "Glucuronic acid epimerase" O94923 15 69160584-69272217 "Enzymes, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.4" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 49.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 58.4" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 4.0;monocytes: 4.4;T-cells: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040481, HPA048216" Uncertain Approved Mitochondria "Intracellular and membrane" 78000 Mitochondria "HPA040481: , HPA048216: " "unprognostic (1.30e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" "unprognostic (7.77e-2)" "unprognostic (1.58e-1)" "unprognostic (5.55e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-1)" "unprognostic (2.56e-1)" "unprognostic (7.47e-2)" "unprognostic (1.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (6.00e-2)" "unprognostic (5.23e-1)" "unprognostic (4.07e-2)" 8.3 12.2 6.5 4.9 14.2 0.6 8.8 58.4 12.1 8.4 12.1 12.4 7.8 13.5 6.3 6.9 10.2 5.9 7.2 5.5 5.8 8.5 13.3 16.0 8.4 5.3 9.4 8.1 12.9 5.9 9.0 12.0 12.6 14.4 5.7 14.0 10.8 11.7 8.9 4.1 9.8 11.2 6.8 10.2 4.0 8.8 6.1 7.6 5.4 4.1 8.4 5.8 6.3 5.6 0.6 4.0 0.1 4.4 0.5 4.0 1.9 3.9 3.5 2.3 4.1 8.0 7.7 0.8 7.3 9.7 5.6 10.8 2.9 9.8 2.3 3.6 5.9 5.8 5.0 4.7 11.6 0.9 5.6 3.9 6.6 2.9 7.8 1.7 8.1 5.2 3.3 7.0 8.0 49.9 1.5 2.5 10.6 2.3 1.0 2.9 1.1 2.4 2.3 9.6 2.9 5.2 4.1 7.6 1.6 7.4 4.6 15.4 3.3 2.4 17.3 5.5 6.8 6.0 6.4 1.0 1.5 0.5 5.5 2.8 7.9 0.0 4.4 0.1 0.7 3.4 1.2 0.6 1.8 0.8 3.6 0.5 1.2 1.5 0.1 0.5 4.4 4.0 4.0 1.9 6.5 14.2 58.4 12.1 5.8 8.5 9.4 8.1 14.4 7.6 GLDC "GCSP, NKH" ENSG00000178445 "Glycine decarboxylase" P23378 9 6532464-6645783 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 22.3;liver: 40.3;placenta: 10.6" "Cell line enhanced" "Detected in some" "BEWO: 65.3;CACO-2: 15.5;HMC-1: 14.2;RPTEC TERT1: 27.0" "Cancer enhanced" "Detected in many" "testis cancer: 41.4" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002318, HPA052887" Enhanced Supported Nucleoplasm,Mitochondria 570000 Mitochondria Nucleoplasm "HPA002318: AB_1849700, HPA052887: " "unprognostic (6.73e-2)" "unprognostic (1.19e-1)" "unprognostic (6.50e-2)" "prognostic unfavourable (5.24e-5)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.74e-1)" "unprognostic (2.47e-2)" "unprognostic (2.69e-1)" "prognostic favourable (3.50e-4)" "unprognostic (1.65e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-3)" "unprognostic (1.17e-2)" 0.2 0.3 3.9 1.0 3.4 0.4 0.4 3.1 5.6 0.3 0.8 1.6 0.0 0.7 0.4 4.2 1.4 0.6 0.6 0.1 2.9 2.2 22.3 40.3 0.8 1.1 1.9 2.9 0.3 0.1 0.0 1.7 10.6 2.1 0.4 0.3 3.2 0.9 0.8 0.9 1.5 0.6 0.1 1.9 0.8 0.8 1.1 1.8 0.0 2.6 0.0 1.9 0.8 0.0 2.9 0.7 2.3 0.5 0.8 0.6 1.1 0.1 1.3 0.5 7.0 0.0 0.1 65.3 0.0 0.0 0.0 0.0 15.5 0.1 0.1 1.5 0.0 0.1 0.0 0.1 0.0 0.3 3.7 0.0 0.0 10.3 0.0 0.0 14.2 0.0 0.0 0.5 0.0 2.7 0.0 0.1 0.3 0.3 0.2 0.0 7.6 1.2 0.3 0.0 0.1 27.0 0.3 6.2 3.2 0.0 6.0 0.0 1.4 0.0 0.9 0.1 0.2 0.7 0.3 0.3 8.9 0.0 0.2 0.7 1.5 1.5 0.5 0.5 0.5 0.3 0.5 2.9 0.6 0.4 0.1 0.9 0.4 0.5 2.3 0.8 0.5 0.7 0.2 1.1 3.9 3.4 3.1 5.6 2.9 2.2 1.9 2.9 2.1 1.8 GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703141 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HMC-1: 244.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" 1600000 "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: " "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (1.08e-2)" "unprognostic (3.96e-3)" "unprognostic (2.51e-1)" "prognostic unfavourable (5.21e-4)" "unprognostic (5.09e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (8.71e-2)" "unprognostic (1.20e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (6.21e-2)" 22.2 30.5 42.1 19.5 42.3 11.4 32.0 25.4 42.3 27.1 42.1 19.7 22.9 48.1 25.3 49.2 28.2 31.5 17.8 39.2 37.8 37.7 37.1 65.3 30.7 31.6 38.9 29.7 37.6 25.9 33.2 12.6 26.7 40.6 74.0 22.7 21.7 21.7 28.2 57.5 31.3 64.3 28.9 37.6 25.6 21.3 12.9 21.4 19.8 32.6 42.5 24.3 28.6 24.7 25.9 28.6 8.5 15.6 10.8 24.4 14.7 18.1 8.4 24.2 24.0 11.5 20.8 21.4 15.8 15.0 22.3 23.2 20.5 7.0 20.2 12.5 12.6 12.0 20.7 20.4 28.3 18.3 32.0 29.9 10.9 19.1 17.3 11.3 244.2 17.7 12.6 21.1 15.1 24.0 23.5 13.4 20.8 15.3 17.7 14.4 17.4 16.5 15.4 29.3 13.2 20.3 13.7 18.9 19.1 11.1 15.5 29.8 18.0 57.1 9.9 17.4 16.0 15.0 25.0 10.6 20.0 55.5 6.3 29.4 27.9 8.5 9.8 6.9 18.0 15.6 24.4 24.7 18.1 18.3 18.3 25.9 17.1 17.9 1.2 10.8 12.1 28.6 15.7 14.7 42.1 42.3 25.4 42.3 37.8 37.7 38.9 29.7 40.6 21.4 GLS "GLS1, KIAA0838" ENSG00000115419 Glutaminase O94925 2 190880827-190965552 "Enzymes, Predicted intracellular proteins" Hydrolase "Cataract, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 127.9" "Cell line enhanced" "Detected in all" "EFO-21: 138.9;RPTEC TERT1: 63.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036223 Enhanced Supported Mitochondria "Intracellular and membrane" 25000 Mitochondria "HPA036223: AB_10669984" "unprognostic (7.45e-2)" "unprognostic (3.42e-2)" "unprognostic (3.21e-1)" "prognostic unfavourable (3.45e-4)" "unprognostic (1.17e-1)" "unprognostic (2.08e-3)" "unprognostic (2.51e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (8.01e-2)" "unprognostic (9.06e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (5.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.12e-1)" 16.5 37.3 37.8 20.4 24.7 10.7 34.3 43.8 47.3 11.9 13.1 5.8 8.9 36.9 14.6 11.9 7.6 11.0 17.7 15.7 23.3 22.8 127.9 5.3 22.6 25.4 20.6 36.8 14.1 17.0 26.4 10.1 14.8 35.1 9.4 13.1 10.8 9.0 13.9 7.4 13.0 40.9 15.5 11.7 19.3 8.7 6.9 12.1 15.0 17.7 8.0 22.9 14.1 16.1 5.2 5.0 6.0 2.1 3.9 9.4 1.5 6.2 7.0 4.9 6.4 15.4 10.7 12.7 18.8 14.3 13.7 15.8 8.5 6.2 12.9 138.9 39.7 8.2 8.6 7.4 20.1 31.8 5.6 21.4 10.3 10.5 14.1 12.5 10.1 9.7 7.7 10.8 7.4 17.8 9.9 26.4 30.5 3.3 8.4 12.1 13.1 11.5 10.7 12.7 11.2 63.8 11.6 6.8 7.1 25.7 5.7 23.9 2.2 7.7 12.6 19.9 14.6 9.9 22.8 8.5 19.4 17.8 7.1 10.3 15.7 6.0 1.5 2.5 5.5 2.1 9.4 4.8 6.5 7.0 2.2 5.2 6.8 8.1 3.0 3.9 1.4 5.0 5.6 1.5 37.8 24.7 43.8 47.3 23.3 22.8 20.6 36.8 35.1 12.1 GLS2 "GA, GLS, hLGA, LGA" ENSG00000135423 "Glutaminase 2" Q9UI32 12 56470944-56488414 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 92.2" "Cell line enhanced" "Detected in some" "Daudi: 25.1;SCLC-21H: 7.1" "Cancer enhanced" "Detected in single" "liver cancer: 1.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 29 "B-cells: 1.8;T-cells: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038608 Uncertain "HPA038608: AB_10673176" "unprognostic (5.59e-2)" "unprognostic (1.51e-2)" "unprognostic (8.73e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "unprognostic (3.27e-3)" "unprognostic (1.98e-6)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.29e-2)" "unprognostic (1.52e-1)" "unprognostic (5.65e-5)" "unprognostic (1.42e-2)" "unprognostic (2.59e-1)" "unprognostic (9.02e-2)" "unprognostic (4.44e-2)" 0.9 1.7 5.7 1.0 8.6 0.9 1.4 12.8 15.0 1.0 1.2 0.2 0.0 1.0 1.2 2.0 1.4 2.8 0.9 1.0 4.2 4.1 1.6 92.2 1.4 1.2 1.9 9.7 1.2 15.8 3.0 6.2 0.8 8.6 1.4 1.7 2.5 1.4 2.0 0.9 2.0 1.0 1.1 3.2 1.1 1.4 1.1 1.4 0.0 1.4 0.0 1.4 1.1 0.8 1.8 0.0 0.0 0.0 0.0 3.8 1.4 4.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 3.4 0.9 25.1 0.4 0.0 0.6 0.0 3.7 0.0 0.0 3.7 0.0 0.3 4.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.8 0.4 0.0 0.1 4.5 2.6 1.7 7.1 0.4 0.8 0.2 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.3 1.8 3.3 1.0 0.0 0.6 3.8 3.5 0.0 0.0 0.0 0.0 0.6 1.4 5.7 8.6 12.8 15.0 4.2 4.1 1.9 9.7 8.6 1.4 GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050486-87094866 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 182.4" "Cell line enhanced" "Detected in all" "Hep G2: 106.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" 26000000 Mitochondria "HPA042492: , HPA044839: , HPA061369: " "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favourable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavourable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favourable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" 15.5 21.5 57.8 9.9 54.5 5.9 23.2 13.4 37.9 12.1 14.5 19.9 5.5 18.4 10.9 7.5 17.0 11.5 12.6 16.7 44.1 35.3 56.2 182.4 13.1 11.5 40.6 30.8 17.5 15.2 8.7 6.6 13.5 31.1 26.5 14.6 8.1 10.0 13.3 9.2 15.3 19.8 14.0 22.7 10.2 12.2 6.4 33.2 12.6 16.1 8.7 13.1 14.0 9.5 9.2 15.8 9.2 14.6 13.7 11.9 5.9 24.0 19.5 15.3 25.9 29.1 35.9 16.7 19.0 33.0 18.5 20.3 44.9 23.6 27.1 15.6 27.7 38.0 19.9 19.2 19.8 19.5 15.7 13.1 11.7 106.0 65.0 30.7 19.1 24.7 36.2 20.5 61.4 22.0 13.2 24.5 19.9 17.5 27.6 27.6 17.4 15.7 21.0 19.5 17.6 53.1 19.7 7.9 14.8 17.1 13.6 24.3 18.6 21.6 21.8 9.6 8.5 19.4 19.3 14.7 15.1 32.4 23.2 35.2 5.7 5.5 13.8 9.2 8.7 11.1 10.9 9.2 11.8 10.6 15.8 8.8 10.6 8.5 1.3 13.7 14.6 5.9 11.9 5.9 57.8 54.5 13.4 37.9 44.1 35.3 40.6 30.8 31.1 33.2 GLUD2 GLUDP1 ENSG00000182890 "Glutamate dehydrogenase 2" P49448 X 121047588-121050080 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 11.3;testis: 31.9" "Cell line enhanced" "Detected in some" "HAP1: 7.8;K-562: 8.6;SK-MEL-30: 11.1;THP-1: 5.5;WM-115: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "HPA042492, HPA044839, HPA061369" Uncertain Supported Mitochondria Mitochondria "HPA042492: , HPA044839: , HPA061369: " "unprognostic (1.44e-1)" "unprognostic (5.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (2.42e-1)" "unprognostic (2.61e-1)" "unprognostic (2.35e-1)" "prognostic favourable (1.98e-4)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (4.77e-3)" "unprognostic (5.96e-2)" 3.1 2.5 4.8 0.8 7.3 0.5 1.6 2.2 3.5 1.1 0.7 2.0 0.6 0.6 1.0 5.2 0.7 1.0 1.6 1.5 5.7 1.8 4.7 11.3 0.9 0.9 2.7 6.2 0.7 1.5 0.7 0.7 2.7 4.3 0.8 0.6 0.2 0.9 3.1 0.7 0.8 1.0 1.0 1.5 0.5 0.9 31.9 4.1 0.0 1.4 0.0 0.8 0.8 0.6 0.8 1.2 0.7 1.1 1.2 0.7 0.4 0.0 2.1 0.5 0.0 0.0 0.0 0.1 0.6 0.6 0.1 0.3 0.0 1.1 0.0 0.8 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 8.6 0.0 0.0 1.7 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 11.1 2.7 5.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.5 0.6 0.8 0.7 0.4 1.1 0.7 0.8 0.7 0.7 1.2 0.4 0.7 0.5 0.0 1.2 1.1 0.2 0.7 0.4 4.8 7.3 2.2 3.5 5.7 1.8 2.7 6.2 4.3 4.1 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182381704-182392206 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 138.5;ASC TERT1: 97.9;HSkMC: 84.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 92.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 92.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported Mitochondria,Cytosol 28000 "Mitochondria, Cytosol" "CAB008636: AB_1616669, HPA007316: AB_1078981, HPA007571: AB_1078980" "prognostic favourable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 173.3 19.2 83.7 37.2 91.0 47.6 63.1 48.5 80.7 41.9 20.4 49.9 9.4 6.2 20.5 29.7 54.0 31.6 26.2 23.5 74.0 48.7 15.6 64.9 39.5 36.9 71.0 48.8 66.2 49.0 7.4 8.9 41.8 70.6 17.4 23.3 39.3 30.4 25.5 159.8 27.9 16.4 30.5 51.3 36.1 71.4 24.0 55.2 8.6 63.9 15.5 24.2 34.7 32.2 2.5 11.0 92.2 21.1 3.4 6.3 18.6 2.9 1.2 13.7 0.0 138.5 97.9 10.1 5.0 16.2 3.0 2.7 7.2 3.0 2.5 5.4 9.7 6.8 5.9 35.6 2.5 6.8 16.6 33.5 5.7 14.0 7.3 14.7 26.8 84.6 42.8 3.8 45.4 6.1 28.2 1.5 10.7 1.6 22.9 14.1 10.1 6.4 8.3 3.6 4.3 5.3 13.0 9.4 6.2 1.4 18.3 1.9 17.8 18.7 4.5 0.1 0.2 0.0 1.1 0.5 0.3 0.0 2.6 8.4 0.5 43.6 21.1 54.9 6.3 20.5 2.6 1.6 4.5 5.2 11.0 2.5 2.3 3.9 92.2 3.4 17.1 6.1 1.7 18.6 83.7 91.0 48.5 80.7 74.0 48.7 71.0 48.8 70.6 55.2 GLYAT "ACGNAT, GAT" ENSG00000149124 Glycine-N-acyltransferase Q6IB77 11 58640426-58731974 "Enzymes, Predicted intracellular proteins" Detoxification "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "kidney: 91.2;liver: 115.1" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in some" 158 "liver cancer: 21.7;renal cancer: 25.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "neutrophil: 2.9" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 0.7" "HPA040251, HPA044094" Enhanced "HPA040251: AB_2676902, HPA044094: AB_2678807" "unprognostic (2.15e-2)" "unprognostic (9.38e-4)" "unprognostic (4.60e-2)" "unprognostic (1.65e-3)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "prognostic favourable (1.31e-6)" "unprognostic (2.69e-1)" 11.1 0.0 0.1 0.1 0.1 0.0 1.8 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 4.5 0.1 0.0 0.1 0.2 0.1 0.0 91.2 115.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.3 1.1 0.7 2.9 0.7 0.2 0.8 0.0 1.5 0.6 1.0 3.2 3.2 2.1 2.1 0.8 0.9 1.5 0.8 0.4 2.0 2.4 1.3 1.4 1.5 2.3 2.4 1.9 0.1 0.7 3.1 0.6 3.3 2.4 1.8 1.8 2.4 7.5 2.6 2.6 2.9 0.9 1.3 3.7 1.2 2.0 3.5 2.9 1.0 1.3 2.2 0.5 6.7 1.6 0.8 2.5 1.7 1.3 1.4 2.3 1.5 1.6 1.8 1.9 2.1 1.2 1.5 2.2 1.1 0.6 4.5 2.0 1.0 0.7 0.3 0.4 0.3 0.4 0.1 0.4 0.8 0.2 1.1 0.5 0.5 2.9 0.2 0.3 0.7 0.5 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 GLYATL1 "FLJ34646, MGC15397" ENSG00000166840 "Glycine-N-acyltransferase like 1" Q969I3 11 58905398-59043527 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 113.8" "Cell line enhanced" "Detected in some" "CACO-2: 3.9;Daudi: 9.6;RPTEC TERT1: 3.2;U-2197: 2.5" "Group enriched" "Detected in some" 8 "liver cancer: 14.1;prostate cancer: 13.3;renal cancer: 10.1" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "naive CD4 T-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" HPA039501 Supported Uncertain "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA039501: " "unprognostic (9.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.90e-5)" "unprognostic (3.93e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-1)" "prognostic favourable (3.69e-4)" "unprognostic (3.62e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (2.92e-1)" "prognostic favourable (3.03e-5)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.1 27.7 113.8 0.1 0.0 0.2 0.0 0.2 0.2 0.9 0.1 0.0 0.5 2.1 0.0 0.5 1.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.0 0.1 1.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.4 1.3 0.0 0.5 0.2 1.1 0.8 3.9 0.0 9.6 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.4 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.4 3.2 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.2 0.1 2.5 1.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.5 0.1 GLYATL2 "BXMAS2-10, MGC24009" ENSG00000156689 "Glycine-N-acyltransferase like 2" Q8WU03 11 58834065-58904215 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 11.2;cervix, uterine: 18.8;lymphoid tissue: 9.9;salivary gland: 25.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 5.8;BJ hTERT+ SV40 Large T+ RasG12V: 4.1;HAP1: 6.5;SK-BR-3: 15.5;U-2197: 7.5" "Cancer enhanced" "Detected in many" "breast cancer: 16.7;endometrial cancer: 15.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Not detected" "Not detected" "HPA060292, HPA065454" Uncertain Approved Mitochondria Mitochondria "HPA060292: , HPA065454: " "unprognostic (1.02e-2)" "unprognostic (3.79e-3)" "unprognostic (8.11e-4)" "prognostic favourable (9.05e-7)" "unprognostic (1.05e-1)" "unprognostic (8.41e-2)" "unprognostic (2.66e-2)" "unprognostic (9.98e-3)" "unprognostic (1.27e-1)" "unprognostic (9.18e-3)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (7.42e-5)" "unprognostic (7.79e-3)" "unprognostic (8.28e-2)" "unprognostic (9.11e-3)" "unprognostic (2.31e-2)" 0.4 0.0 0.4 0.1 0.2 0.0 11.2 0.1 0.3 18.8 0.1 0.1 0.1 0.1 1.2 0.1 0.8 0.1 6.6 0.2 0.3 0.4 0.1 0.1 0.6 0.2 0.6 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.7 0.0 0.1 25.8 0.1 0.1 1.2 0.1 0.1 1.5 1.1 0.1 0.1 0.1 0.1 0.1 4.4 9.9 0.1 0.3 0.4 0.1 2.1 0.4 0.2 0.2 0.9 0.0 0.0 0.5 0.0 0.9 3.0 0.0 1.9 5.8 2.5 4.1 0.0 0.0 0.2 0.0 1.6 0.5 6.5 0.0 2.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.3 0.6 0.0 0.6 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.2 15.5 0.0 0.0 0.0 0.0 2.1 0.1 7.5 2.2 0.0 0.0 0.1 0.0 0.0 0.8 0.8 0.2 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.1 2.1 0.2 0.0 0.1 0.0 0.9 0.4 0.2 0.1 0.3 0.3 0.4 0.6 0.1 0.1 0.1 GLYCTK "HBEBP2, HBEBP4" ENSG00000168237 "Glycerate kinase" Q8IVS8 3 52287089-52293476 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 108.4" "Cell line enhanced" "Detected in many" "CACO-2: 18.9;Hep G2: 25.1" "Cancer enriched" "Detected in all" 6 "liver cancer: 52.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006913 Approved Approved "Golgi apparatus,Cytosol,Rods & Rings" Cytosol "Golgi apparatus, Rods & Rings" "HPA006913: AB_1078993" "unprognostic (1.51e-2)" "unprognostic (2.55e-1)" "unprognostic (1.25e-1)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "prognostic favourable (1.64e-4)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (7.73e-3)" "unprognostic (1.82e-1)" "unprognostic (3.36e-3)" "unprognostic (2.15e-1)" "unprognostic (3.30e-2)" "unprognostic (3.42e-1)" "unprognostic (3.77e-1)" "unprognostic (3.82e-2)" "unprognostic (9.00e-3)" 6.4 4.9 1.9 8.4 5.0 5.2 4.8 2.7 6.2 2.3 7.9 7.1 4.2 23.8 4.3 4.8 2.8 2.5 7.2 2.7 1.9 2.2 10.7 108.4 3.1 6.5 2.5 4.9 2.3 3.6 1.9 2.5 3.1 3.9 2.8 3.5 4.7 3.2 3.0 7.0 1.9 17.8 1.9 1.8 5.5 6.0 2.7 1.8 3.3 3.1 2.4 5.9 2.7 2.2 8.3 9.1 10.9 9.5 5.7 11.8 6.3 2.2 5.5 3.0 1.1 16.0 2.2 1.8 2.5 2.6 4.7 3.5 18.9 1.9 5.9 1.5 2.2 1.5 1.7 6.2 0.9 1.6 1.9 8.3 6.7 25.1 1.5 2.7 5.0 2.1 3.1 6.9 2.7 9.0 2.2 4.3 3.6 1.7 4.6 2.2 1.6 4.6 1.5 2.7 8.9 4.8 3.1 2.2 2.2 2.4 1.3 2.5 3.1 1.3 3.8 3.7 4.4 2.4 4.8 4.5 3.1 3.8 2.5 4.5 2.8 3.0 9.5 10.9 11.8 5.1 6.1 8.3 9.0 10.3 9.1 5.7 6.8 10.1 7.8 5.7 6.1 5.6 11.7 6.3 1.9 5.0 2.7 6.2 1.9 2.2 2.5 4.9 3.9 1.8 GMDS "GMD, SDR3E1" ENSG00000112699 "GDP-mannose 4,6-dehydratase" O60547 6 1623806-2245692 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031528 Enhanced 41000 "HPA031528: AB_10601016" "unprognostic (5.94e-2)" "unprognostic (3.92e-2)" "unprognostic (1.12e-1)" "prognostic favourable (5.89e-4)" "unprognostic (4.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.10e-3)" "unprognostic (7.15e-2)" "unprognostic (2.29e-1)" "unprognostic (8.02e-2)" "unprognostic (2.38e-1)" "unprognostic (4.41e-1)" "prognostic favourable (5.93e-4)" "unprognostic (2.45e-1)" "unprognostic (2.84e-1)" "unprognostic (6.68e-2)" "unprognostic (1.12e-1)" 5.1 4.0 6.6 29.6 8.7 3.2 7.6 6.0 6.8 12.9 34.9 2.7 10.4 42.1 4.1 6.4 29.2 4.9 38.5 4.9 5.6 4.6 9.3 15.1 7.8 11.8 4.1 3.7 4.3 27.1 19.3 8.9 3.0 4.0 8.6 34.2 6.3 40.4 7.6 3.3 4.9 43.7 4.4 3.1 6.0 38.4 9.0 3.4 9.3 5.6 9.0 19.6 6.1 6.7 10.5 13.9 6.8 12.3 12.0 12.4 7.3 16.9 4.0 2.8 20.1 4.7 12.8 6.9 4.7 9.8 8.8 8.3 8.6 9.9 8.1 14.5 5.1 6.7 8.7 16.6 10.2 11.1 10.6 7.8 4.4 40.7 5.2 12.5 8.7 14.1 5.7 6.9 14.6 10.2 5.0 3.8 5.6 9.7 17.2 14.8 4.3 13.5 9.0 6.5 41.5 21.2 22.4 16.1 3.8 4.3 6.8 10.4 6.3 7.9 4.4 6.8 5.0 6.8 8.3 8.6 12.1 8.6 4.4 8.8 8.9 6.8 12.3 1.4 7.9 7.6 10.6 10.5 9.5 7.8 13.9 5.5 8.3 11.1 3.8 12.0 6.1 5.8 12.4 7.3 6.6 8.7 6.0 6.8 5.6 4.6 4.1 3.7 4.0 3.4 GMPPB KIAA1851 ENSG00000173540 "GDP-mannose pyrophosphorylase B" Q9Y5P6 3 49716844-49723951 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014657 Uncertain Supported Nucleoplasm 10000 Nucleoplasm "HPA014657: AB_1849852" "unprognostic (3.48e-2)" "unprognostic (9.84e-2)" "unprognostic (2.77e-2)" "prognostic favourable (6.19e-6)" "unprognostic (1.01e-2)" "unprognostic (5.11e-3)" "unprognostic (1.54e-2)" "unprognostic (4.01e-3)" "unprognostic (1.04e-1)" "unprognostic (1.99e-2)" "unprognostic (5.01e-3)" "unprognostic (5.73e-2)" "prognostic favourable (3.17e-4)" "unprognostic (1.60e-1)" "unprognostic (1.79e-1)" "unprognostic (1.67e-1)" "unprognostic (1.22e-1)" 7.5 17.1 7.6 17.5 8.1 7.4 9.7 4.3 9.6 14.4 13.2 7.2 28.7 12.1 11.5 23.2 15.3 12.6 13.3 10.9 5.2 4.7 13.1 41.3 12.9 15.9 8.3 6.8 10.1 32.0 8.9 23.0 15.3 6.9 16.6 11.3 7.9 50.8 37.2 7.2 8.2 12.2 7.9 4.3 16.8 18.1 6.9 5.8 16.5 16.8 8.6 17.5 8.8 9.3 13.4 34.5 10.1 11.1 5.5 11.2 8.1 17.6 17.2 12.5 7.6 10.0 7.6 12.9 20.4 12.1 20.7 19.7 11.2 13.1 10.3 9.1 12.7 10.2 10.4 22.0 7.0 9.3 8.6 7.4 19.1 13.2 23.1 11.2 11.9 5.3 9.5 29.3 23.4 18.7 5.5 17.1 11.9 13.3 15.1 5.7 6.9 20.8 5.3 6.4 17.7 11.5 16.6 8.3 8.8 9.3 22.7 6.7 12.9 7.3 12.9 14.9 14.5 20.2 21.8 19.7 5.3 7.3 15.8 7.9 17.1 10.1 8.6 3.7 10.8 11.0 11.0 13.4 9.5 11.2 8.2 10.3 7.3 8.8 2.2 5.5 11.1 34.5 6.3 8.1 7.6 8.1 4.3 9.6 5.2 4.7 8.3 6.8 6.9 5.8 GMPR ENSG00000137198 "Guanosine monophosphate reductase" P36959 6 16238580-16295549 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Purine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 103.3" "Cell line enhanced" "Detected in many" "HEL: 45.2;HMC-1: 77.1;SK-MEL-30: 17.2" "Cancer enhanced" "Detected in all" "melanoma: 95.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 7.8;NK-cell: 8.3" "Group enriched" "Detected in many" 5 "granulocytes: 7.8;monocytes: 4.2;NK-cells: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000904, HPA021476" Uncertain 3800000 "HPA000904: AB_1078998, HPA021476: AB_1849858" "unprognostic (2.74e-1)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" "unprognostic (4.97e-3)" "unprognostic (3.52e-2)" "unprognostic (1.05e-1)" "unprognostic (3.06e-1)" "prognostic favourable (8.07e-4)" "unprognostic (4.12e-1)" "prognostic favourable (2.06e-4)" "unprognostic (3.15e-1)" "unprognostic (2.86e-1)" "prognostic favourable (2.94e-5)" "unprognostic (3.01e-1)" "unprognostic (1.81e-1)" "unprognostic (7.31e-2)" "unprognostic (2.17e-1)" 2.8 7.3 14.6 1.4 11.0 9.6 6.5 3.8 6.9 2.7 3.7 9.1 2.0 1.5 4.2 7.9 2.5 22.4 1.9 31.5 13.3 11.5 10.3 2.7 3.7 2.5 14.0 5.7 15.7 7.4 4.4 6.8 3.4 21.3 25.5 1.8 22.0 5.2 4.2 103.3 4.3 1.5 4.3 11.8 3.3 8.3 25.1 10.9 1.4 2.7 16.2 1.5 2.0 1.2 0.7 1.3 7.8 4.2 8.3 1.0 14.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.9 3.7 6.6 13.6 0.3 0.1 0.0 2.1 1.4 0.0 1.6 0.2 1.1 0.0 1.2 45.2 0.0 0.0 2.9 0.2 77.1 0.9 0.7 2.0 0.0 11.9 10.0 0.0 1.1 0.8 0.0 0.9 0.4 1.8 0.0 10.2 0.0 8.8 1.2 2.3 0.3 0.4 0.7 17.2 0.7 0.3 2.9 0.1 0.0 0.3 1.7 0.5 0.0 0.0 0.2 4.8 5.2 7.8 2.9 0.4 0.6 4.2 1.0 0.2 0.1 0.4 1.3 0.7 0.0 0.2 3.0 8.3 1.3 1.2 0.0 14.1 14.6 11.0 3.8 6.9 13.3 11.5 14.0 5.7 21.3 10.9 GMPR2 ENSG00000100938 "Guanosine monophosphate reductase 2" Q9P2T1 14 24232422-24239242 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Purine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000904, HPA067884, HPA068782" Uncertain Approved Nucleoplasm,Nucleoli 160000 Nucleoplasm Nucleoli "HPA000904: AB_1078998, HPA067884: , HPA068782: " "unprognostic (1.95e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (1.03e-1)" "unprognostic (9.86e-2)" "unprognostic (5.98e-2)" "unprognostic (3.24e-1)" "unprognostic (5.21e-3)" "unprognostic (9.24e-2)" "unprognostic (3.08e-1)" "unprognostic (7.88e-2)" "unprognostic (1.16e-1)" "prognostic favourable (2.21e-5)" "unprognostic (2.30e-1)" "unprognostic (1.96e-1)" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" 18.9 44.2 19.6 14.6 24.2 11.5 26.2 13.6 31.7 22.5 21.1 25.1 20.3 21.3 18.8 26.3 17.8 28.7 23.4 15.0 20.1 21.9 39.1 26.3 19.0 18.1 23.0 21.2 26.1 26.9 49.1 22.4 22.7 26.0 20.3 21.6 21.9 22.6 23.7 16.1 14.4 21.7 18.2 20.3 25.5 21.2 10.6 19.1 21.6 43.0 11.2 21.0 21.8 17.6 7.5 14.4 32.3 14.0 7.6 14.9 11.0 9.0 10.4 14.1 9.2 16.3 23.1 12.8 10.7 19.1 15.1 19.3 12.2 7.2 12.1 9.8 15.7 12.6 15.5 23.2 21.5 11.4 11.4 9.5 6.5 44.5 15.3 15.6 15.0 21.7 16.7 7.9 16.5 24.4 5.5 11.5 15.2 16.9 15.4 14.0 10.9 13.5 11.7 9.5 10.0 20.7 15.0 10.0 14.1 7.7 16.9 14.4 14.7 12.5 12.5 7.1 5.7 9.4 7.8 25.5 24.4 7.9 5.9 11.9 6.9 9.0 14.0 7.2 10.1 11.2 10.7 7.5 10.2 11.2 14.4 7.1 9.1 10.2 32.3 7.6 11.3 6.5 14.9 11.0 19.6 24.2 13.6 31.7 20.1 21.9 23.0 21.2 26.0 19.1 GMPS GATD7 ENSG00000163655 "Guanine monophosphate synthase" P49915 3 155870536-155944026 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" Ligase Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046630 Approved Cytosol Cytosol "HPA046630: " "unprognostic (3.89e-2)" "unprognostic (2.02e-2)" "unprognostic (1.59e-2)" "prognostic unfavourable (5.54e-5)" "unprognostic (2.30e-1)" "unprognostic (1.35e-2)" "prognostic unfavourable (8.73e-7)" "unprognostic (1.71e-2)" "unprognostic (3.52e-2)" "unprognostic (1.77e-2)" "prognostic unfavourable (1.04e-4)" "unprognostic (2.58e-2)" "unprognostic (2.79e-2)" "unprognostic (2.89e-2)" "unprognostic (3.78e-1)" "unprognostic (3.55e-3)" "unprognostic (8.79e-2)" 15.9 18.3 10.4 19.7 14.0 24.6 22.4 22.1 24.9 16.1 13.9 9.8 15.3 10.3 17.5 15.4 19.5 14.0 10.8 15.3 9.2 7.7 11.0 14.7 15.8 19.5 9.3 12.1 15.7 23.5 19.1 14.1 13.5 14.8 13.0 15.3 9.0 21.6 18.6 16.6 21.0 12.6 16.1 8.9 14.6 15.4 60.9 10.5 28.3 13.6 12.5 18.4 15.9 18.5 11.1 17.2 10.9 18.1 19.0 20.7 10.8 55.8 22.1 30.1 24.5 12.2 19.4 29.0 23.8 22.1 31.5 31.9 40.3 37.7 40.4 28.5 18.3 27.5 25.5 25.0 43.4 23.4 19.6 43.0 16.2 21.8 14.0 43.7 16.8 14.3 15.4 24.3 37.3 19.3 30.2 15.5 23.4 37.5 35.4 23.1 28.8 16.4 34.9 35.6 48.7 16.2 24.6 18.0 16.7 26.5 38.0 23.8 39.7 28.8 13.5 20.9 16.9 29.5 48.0 21.7 13.3 69.1 21.0 32.6 18.6 10.9 10.4 7.2 17.3 13.1 20.7 11.1 16.8 15.7 17.2 8.8 16.8 15.8 1.4 19.0 18.1 9.5 17.6 10.8 10.4 14.0 22.1 24.9 9.2 7.7 9.3 12.1 14.8 10.5 GNE "IBM2, Uae1" ENSG00000159921 "Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase" Q9Y223 9 36214441-36277056 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 55.0;salivary gland: 45.3" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007045, HPA027258" Approved Supported Cytosol Cytosol "HPA007045: AB_1079003, HPA027258: AB_1849873" "unprognostic (7.54e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-3)" "unprognostic (7.28e-2)" "unprognostic (7.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.78e-3)" "unprognostic (5.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.88e-3)" "unprognostic (4.20e-2)" "prognostic favourable (9.28e-11)" "unprognostic (2.90e-1)" "unprognostic (8.28e-2)" "unprognostic (2.95e-1)" "unprognostic (1.72e-2)" 7.7 6.7 6.0 6.5 8.3 8.3 16.6 11.1 12.1 7.9 20.7 7.0 4.6 2.9 8.0 3.9 7.6 6.7 5.2 7.6 7.8 6.8 6.8 55.0 5.5 6.0 6.0 7.8 9.8 8.4 4.1 7.0 20.2 10.2 10.1 30.1 4.8 45.3 5.0 10.5 3.7 7.2 11.7 10.9 4.5 4.9 3.4 5.3 3.2 4.6 4.2 7.9 8.6 7.9 3.9 2.2 1.2 2.7 2.4 4.2 1.8 4.4 19.9 8.9 7.6 10.1 10.1 12.9 6.2 7.9 8.6 11.1 4.8 14.2 5.8 6.6 10.3 1.7 6.7 2.0 9.6 10.9 0.6 5.0 11.7 6.6 6.9 0.1 14.3 6.6 2.0 14.3 13.5 3.6 6.3 12.1 8.3 0.7 8.1 2.6 5.1 11.2 6.7 7.5 1.6 47.6 8.2 7.6 6.9 6.6 2.3 5.7 2.1 5.1 5.2 5.7 5.9 6.8 5.4 5.3 11.3 3.2 7.8 4.3 8.1 0.7 1.7 0.9 2.7 2.2 1.8 2.4 3.4 2.9 1.4 3.9 4.0 4.2 1.2 2.4 2.7 2.2 1.5 1.8 6.0 8.3 11.1 12.1 7.8 6.8 6.0 7.8 10.2 5.3 GNMT ENSG00000124713 "Glycine N-methyltransferase" Q14749 6 42960758-42963880 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 83.9;pancreas: 100.1" "Cell line enhanced" "Detected in many" "Hep G2: 10.3;SCLC-21H: 12.2;T-47d: 7.8" "Group enriched" "Detected in many" 20 "liver cancer: 69.6;prostate cancer: 49.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in some" 4 "cerebellum: 17.7" "Low region specificity" "Detected in all" HPA027501 Enhanced Approved Cytosol 150000 Cytosol "HPA027501: AB_1849879" "unprognostic (1.53e-2)" "unprognostic (8.02e-4)" "unprognostic (3.11e-2)" "unprognostic (4.24e-3)" "unprognostic (3.91e-2)" "unprognostic (6.40e-4)" "prognostic favourable (1.86e-4)" "unprognostic (4.08e-6)" "unprognostic (1.01e-1)" "unprognostic (2.67e-2)" "unprognostic (1.63e-3)" "unprognostic (2.52e-1)" "unprognostic (3.50e-3)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (2.49e-2)" "unprognostic (4.92e-2)" 0.3 0.1 0.2 0.2 0.2 0.7 1.8 0.5 0.5 0.3 0.5 0.2 1.3 0.0 0.2 0.9 0.3 0.1 0.2 1.3 0.2 0.2 0.3 83.9 1.3 0.1 0.1 0.2 0.4 100.1 0.0 2.5 0.1 0.4 5.2 0.0 0.9 8.2 0.9 0.6 0.1 0.2 0.4 0.1 0.3 6.5 0.6 0.1 0.2 0.9 0.3 0.4 0.2 0.1 0.7 3.2 2.0 0.9 0.0 1.2 0.3 0.5 0.4 1.8 5.0 0.6 0.2 0.3 0.4 2.0 0.8 1.2 0.1 0.1 1.6 0.2 0.4 0.5 0.3 0.3 0.2 2.0 1.6 1.3 1.0 10.3 0.0 1.1 2.4 0.4 0.0 0.4 0.2 0.0 1.4 1.9 0.3 2.2 2.0 3.7 0.2 0.5 1.7 1.6 1.0 0.8 0.2 12.2 1.7 0.1 1.7 0.6 7.8 3.5 0.4 0.9 0.9 0.5 1.0 1.3 1.1 1.4 0.2 2.0 1.0 0.0 0.8 0.1 0.2 0.9 0.1 0.7 0.3 0.3 0.9 0.1 0.6 1.2 2.0 0.0 0.1 3.2 0.3 0.3 0.2 0.2 0.5 0.5 0.2 0.2 0.1 0.2 0.4 0.1 GNPDA1 "GNPDA, GNPI, GPI, HLN, KIAA0060" ENSG00000113552 "Glucosamine-6-phosphate deaminase 1" P46926 5 141991749-142013041 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" 970000 Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: " "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (6.79e-2)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (8.89e-3)" "prognostic unfavourable (2.60e-6)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.09e-1)" "unprognostic (1.58e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (9.66e-2)" "unprognostic (2.05e-3)" 15.6 28.2 13.9 10.0 19.1 4.3 18.7 12.6 22.5 16.5 13.7 13.2 11.7 18.0 24.8 34.0 10.7 11.9 13.7 10.6 12.3 16.1 46.2 10.2 11.0 21.8 14.1 16.5 20.7 7.7 15.1 19.9 18.9 13.4 17.8 14.0 17.1 10.6 18.9 16.5 9.0 18.8 18.4 10.9 18.2 9.5 16.3 10.8 12.4 18.2 9.2 11.8 23.6 11.2 7.9 20.6 5.0 22.7 5.6 32.7 14.7 11.7 17.2 6.8 33.2 23.1 15.7 15.7 9.3 22.5 24.8 28.3 25.7 14.0 0.0 21.4 6.7 12.5 31.2 27.8 22.0 9.0 13.4 8.6 10.1 18.3 41.1 23.8 11.4 18.7 16.5 15.8 42.2 26.0 10.2 31.8 26.5 7.4 18.1 2.7 25.2 34.8 7.1 21.8 26.2 23.9 32.5 6.0 15.7 18.5 19.3 35.4 15.8 7.5 12.4 14.5 9.9 22.3 13.1 17.9 34.2 13.2 21.3 8.2 12.6 0.0 19.4 2.6 15.7 22.7 32.7 7.9 12.8 14.4 20.6 3.7 15.5 16.5 5.0 5.6 20.4 11.6 10.6 14.7 13.9 19.1 12.6 22.5 12.3 16.1 14.1 16.5 13.4 10.8 GNPDA2 SB52 ENSG00000163281 "Glucosamine-6-phosphate deaminase 2" Q8TDQ7 4 44682200-44726595 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" 710000 Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: " "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (1.90e-2)" "unprognostic (3.29e-1)" "unprognostic (1.55e-3)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "unprognostic (9.57e-2)" "unprognostic (9.75e-3)" "unprognostic (1.03e-1)" "unprognostic (1.28e-3)" "unprognostic (4.18e-2)" "unprognostic (6.86e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" 12.3 13.7 14.8 11.2 21.5 7.3 14.9 47.5 24.5 15.2 12.3 7.3 8.7 8.0 17.5 15.3 11.2 13.3 10.8 17.8 14.5 13.9 14.3 4.3 10.0 11.7 13.7 17.6 24.2 8.1 13.0 29.9 6.6 16.5 15.7 8.5 11.5 9.8 16.2 10.9 10.2 8.7 16.6 12.7 11.4 9.9 11.1 11.3 10.0 18.9 8.4 10.2 13.5 11.0 11.6 3.3 5.8 4.1 8.4 11.4 4.4 9.0 6.3 6.8 5.7 10.6 14.8 2.2 16.1 17.5 10.3 9.7 3.2 11.1 7.8 9.3 13.7 3.1 6.2 15.0 11.7 10.4 7.1 11.2 10.3 5.6 11.8 11.7 10.4 17.4 10.6 10.6 7.9 15.4 6.7 10.4 19.5 0.4 14.0 6.6 3.2 11.7 9.3 14.5 4.4 10.3 5.4 11.7 9.5 7.0 4.1 15.2 8.8 6.9 15.8 14.2 13.3 22.8 18.2 13.5 21.3 11.3 23.2 8.3 12.6 5.8 2.3 4.5 9.7 3.3 11.3 11.6 9.1 9.0 3.3 10.4 11.4 10.9 1.1 8.4 4.1 2.6 9.6 4.4 14.8 21.5 47.5 24.5 14.5 13.9 13.7 17.6 16.5 11.3 GNPNAT1 "FLJ10607, Gpnat1" ENSG00000100522 "Glucosamine-phosphate N-acetyltransferase 1" Q96EK6 14 52775194-52791668 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044647 Approved 17000 "HPA044647: AB_10795986" "unprognostic (4.55e-3)" "unprognostic (1.19e-2)" "unprognostic (4.47e-3)" "unprognostic (5.18e-3)" "unprognostic (4.23e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (3.19e-3)" "unprognostic (1.03e-1)" "unprognostic (6.81e-2)" "prognostic unfavourable (8.52e-5)" "unprognostic (5.82e-2)" "unprognostic (3.22e-3)" "unprognostic (2.16e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "unprognostic (4.05e-2)" 13.4 6.9 6.4 6.7 6.6 2.1 10.6 9.2 9.2 10.0 11.2 4.6 6.8 9.3 8.1 6.4 8.4 6.3 9.3 6.3 5.8 6.3 11.5 47.3 6.4 8.6 5.4 5.2 9.3 28.4 6.9 12.4 6.5 7.1 10.1 14.0 4.1 22.2 4.7 9.4 4.8 8.5 8.2 6.3 7.3 12.0 12.5 4.2 3.6 5.4 6.0 7.1 7.3 7.2 6.1 5.1 6.6 5.7 7.7 8.4 4.2 34.1 13.7 10.8 12.3 11.8 26.7 17.9 22.3 14.4 19.5 20.2 15.5 20.3 19.5 12.5 22.0 13.9 20.8 22.4 33.8 11.1 11.1 13.0 13.1 19.2 17.0 14.4 7.1 11.1 19.2 33.0 35.3 21.8 12.6 4.8 24.9 29.7 17.3 7.5 11.4 24.1 12.0 5.0 11.7 18.4 18.3 11.2 15.4 18.5 25.0 15.9 28.6 5.0 24.2 19.8 20.8 35.0 17.2 5.0 9.6 8.6 9.3 9.5 11.5 6.6 2.2 0.1 7.1 2.7 8.4 6.1 7.3 6.2 5.1 5.4 8.4 6.8 0.7 7.7 5.7 3.2 8.4 4.2 6.4 6.6 9.2 9.2 5.8 6.3 5.4 5.2 7.1 4.2 GNPTAB "GNPTA, KIAA1208, MGC4170" ENSG00000111670 "N-acetylglucosamine-1-phosphate transferase alpha and beta subunits" Q3T906 12 101745497-101830938 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Cancer-related genes, Disease mutation, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014558, HPA042343" Approved Supported "Golgi apparatus" 47000 "Golgi apparatus" "HPA014558: , HPA042343: " "unprognostic (6.72e-2)" "unprognostic (1.66e-1)" "unprognostic (8.71e-3)" "prognostic favourable (8.48e-4)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (2.73e-1)" "unprognostic (8.57e-2)" "unprognostic (3.73e-2)" "unprognostic (1.09e-2)" "unprognostic (2.28e-2)" "unprognostic (2.00e-1)" "unprognostic (6.86e-2)" "unprognostic (3.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.44e-2)" "unprognostic (4.98e-2)" 15.2 6.5 21.9 11.9 23.0 15.2 12.2 13.9 25.6 14.0 21.3 10.3 5.9 10.3 9.0 6.5 11.7 7.1 11.0 15.9 17.9 13.7 11.0 7.3 19.6 20.3 14.4 13.0 6.6 11.4 29.9 9.0 10.8 10.9 15.6 22.5 11.3 37.6 10.2 10.8 18.1 14.5 11.7 13.1 15.4 15.2 7.4 10.8 24.5 10.5 8.6 12.6 14.7 14.8 3.9 5.8 5.9 3.4 14.2 16.4 2.7 8.3 8.1 3.0 5.1 25.6 12.2 9.4 11.9 24.6 11.8 15.5 6.2 5.9 17.5 8.6 16.3 10.9 14.0 15.3 18.5 8.2 7.3 7.5 7.5 8.8 4.8 6.8 15.2 9.4 8.5 11.2 6.6 20.7 11.6 5.2 11.0 12.7 20.4 9.6 10.4 5.9 4.8 15.5 23.5 19.0 21.7 6.6 5.4 19.8 14.1 28.0 14.5 4.5 20.3 11.2 6.1 9.3 6.6 14.3 14.6 10.0 12.7 10.1 6.9 5.9 3.1 3.4 16.4 2.9 5.4 2.4 3.6 8.9 5.8 3.9 4.6 7.1 1.2 14.2 3.4 5.8 2.6 2.7 21.9 23.0 13.9 25.6 17.9 13.7 14.4 13.0 10.9 10.8 GNS ENSG00000135677 "Glucosamine (N-acetyl)-6-sulfatase" P15586 12 64713445-64759447 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 73.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "non-classical monocyte: 50.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013695, CAB026011, HPA048508" Enhanced "Intracellular and membrane" 940000 "CAB026011: , HPA013695: AB_1849741, HPA048508: " "unprognostic (8.07e-2)" "unprognostic (2.39e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-2)" "prognostic unfavourable (7.76e-4)" "unprognostic (9.33e-2)" "prognostic unfavourable (1.94e-5)" "unprognostic (1.26e-1)" "unprognostic (4.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.04e-2)" "unprognostic (3.30e-2)" "unprognostic (3.28e-3)" "unprognostic (1.42e-1)" "unprognostic (3.77e-2)" "unprognostic (1.09e-1)" "unprognostic (3.04e-1)" 57.0 96.7 9.0 18.2 10.1 7.4 47.5 7.7 11.6 22.6 19.1 15.4 17.7 11.5 27.1 27.4 14.3 18.7 21.9 33.0 9.0 10.7 48.9 36.7 26.6 48.8 9.6 8.7 32.7 16.0 32.2 16.6 43.5 15.5 18.6 12.8 38.2 17.9 17.1 18.2 13.5 21.6 23.6 10.8 33.6 16.5 19.3 8.4 9.1 31.4 10.4 11.7 23.9 18.2 3.0 18.2 12.9 50.0 3.9 7.0 19.0 8.1 12.6 10.4 17.1 52.4 31.6 22.2 19.0 44.3 22.6 24.9 11.6 11.1 3.5 24.8 24.1 6.7 10.3 10.9 25.6 10.3 7.5 8.3 10.3 7.4 23.8 6.1 73.8 30.2 13.4 23.0 10.5 41.7 5.7 24.8 33.0 6.5 1.5 3.6 4.1 10.7 4.8 16.3 10.8 19.7 24.1 7.1 7.6 24.6 12.0 17.2 21.5 8.2 38.4 22.3 11.8 21.5 11.1 23.5 28.0 3.1 32.1 11.9 15.1 8.8 30.3 5.9 7.0 37.0 5.2 3.0 3.8 5.3 18.2 2.4 4.0 4.0 12.9 3.9 50.0 4.3 2.8 19.0 9.0 10.1 7.7 11.6 9.0 10.7 9.6 8.7 15.5 8.4 GOT1 AST1 ENSG00000120053 "Glutamic-oxaloacetic transaminase 1" P17174 10 99396870-99430624 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 116.9;liver: 82.9;skeletal muscle: 102.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064532, HPA072629" Enhanced Supported Nucleoplasm,Cytosol 130000000 Nucleoplasm Cytosol "HPA064532: AB_2685279, HPA072629: AB_2686540" "unprognostic (6.40e-2)" "prognostic favourable (6.23e-4)" "unprognostic (5.99e-2)" "unprognostic (2.84e-2)" "unprognostic (2.82e-1)" "unprognostic (2.96e-2)" "unprognostic (5.25e-2)" "unprognostic (1.08e-3)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (1.79e-1)" "prognostic favourable (3.72e-13)" "unprognostic (1.93e-2)" "unprognostic (4.23e-1)" "unprognostic (6.85e-2)" "unprognostic (1.00e-1)" 3.3 14.0 15.7 3.6 32.1 2.0 5.9 22.9 56.4 13.5 12.0 9.7 5.9 14.7 3.4 7.0 10.3 4.6 12.2 116.9 19.4 19.0 34.6 82.9 3.5 3.4 17.8 16.4 3.8 8.2 15.9 4.9 3.7 49.9 5.9 14.7 9.0 12.4 7.2 102.1 4.5 12.7 5.4 7.7 3.6 10.1 9.3 4.7 3.3 11.7 31.3 7.1 4.9 4.0 10.6 21.4 3.9 16.8 11.4 15.6 8.8 16.9 9.4 11.1 28.0 8.6 7.4 31.4 13.9 25.6 24.3 26.5 21.3 13.8 16.6 4.8 11.7 21.3 25.3 18.3 26.8 5.7 10.8 6.3 12.1 27.7 45.6 18.0 10.8 11.6 19.8 20.6 55.9 11.7 16.2 26.0 15.5 15.3 9.6 13.5 7.1 13.1 10.5 10.6 17.3 42.4 9.3 4.8 7.1 10.5 14.9 51.9 28.5 6.2 5.4 6.2 13.8 6.7 15.9 18.6 21.9 16.9 16.3 9.4 8.2 2.4 5.3 3.9 12.4 14.7 11.4 10.6 13.5 12.9 12.9 10.2 10.2 14.5 0.5 11.4 16.8 21.4 15.6 8.8 15.7 32.1 22.9 56.4 19.4 19.0 17.8 16.4 49.9 4.7 GOT2 "KAT4, KATIV, KYAT4, mitAAT" ENSG00000125166 "Glutamic-oxaloacetic transaminase 2" P00505 16 58707131-58734357 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 167.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018139 Enhanced "Intracellular and membrane" 7000000 "HPA018139: AB_1849903" "unprognostic (1.50e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-3)" "unprognostic (2.63e-3)" "unprognostic (3.02e-2)" "prognostic unfavourable (1.61e-4)" "prognostic favourable (5.75e-5)" "unprognostic (1.12e-2)" "unprognostic (3.19e-1)" "unprognostic (3.72e-2)" "unprognostic (2.27e-1)" "unprognostic (3.00e-1)" "prognostic favourable (2.90e-9)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (2.22e-1)" 6.1 21.0 12.7 8.0 19.1 5.5 10.7 19.4 35.7 10.6 15.9 16.0 33.3 10.6 10.4 19.5 17.7 13.5 8.9 78.1 15.8 16.7 24.6 85.5 7.1 11.1 16.2 17.8 8.7 8.8 27.0 13.0 7.3 27.7 17.2 18.8 23.4 13.0 20.5 167.8 10.4 9.4 13.5 12.3 8.0 13.6 10.8 9.9 10.7 12.3 53.9 15.0 15.5 11.2 14.3 17.6 3.5 9.9 14.5 24.5 14.3 27.1 36.9 19.5 23.6 14.1 12.8 25.5 20.9 22.3 41.2 22.6 31.9 24.6 60.8 24.9 23.1 40.2 41.6 40.6 52.6 16.7 38.2 16.4 20.1 35.6 17.9 26.2 15.1 12.3 23.1 25.9 22.7 41.3 32.8 6.3 20.9 24.3 32.6 25.4 26.4 71.7 35.8 29.7 58.3 38.9 40.0 31.1 22.6 40.0 43.1 15.0 21.8 8.6 16.6 15.0 27.5 11.7 26.5 14.6 13.5 49.8 16.1 26.3 15.1 2.3 9.9 3.5 15.2 8.6 23.5 14.3 18.0 18.4 17.6 10.6 16.7 15.3 0.9 14.5 8.5 15.5 24.5 14.3 12.7 19.1 19.4 35.7 15.8 16.7 16.2 17.8 27.7 9.9 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149864-112215377 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 107.3;liver: 56.6" "Cell line enhanced" "Detected in all" "ASC diff: 75.2;Hep G2: 20.2" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria Mitochondria "HPA046339: , HPA060090: " "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favourable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 107.3 17.2 11.4 2.6 12.1 1.8 30.8 6.6 11.0 2.0 3.2 6.5 5.1 2.2 4.1 32.1 2.4 1.9 3.0 5.8 12.2 2.9 2.4 56.6 2.2 2.3 7.2 7.3 3.5 2.8 3.2 2.3 1.8 5.6 2.3 2.6 12.0 6.8 2.9 3.6 1.8 3.3 3.4 3.8 1.7 2.4 2.8 7.2 2.8 6.1 2.4 2.3 3.2 1.6 3.2 2.0 0.5 1.2 1.1 3.4 1.0 2.7 2.1 2.8 3.7 75.2 2.7 3.7 2.6 3.0 1.9 1.5 4.9 1.6 1.9 1.4 1.8 3.5 4.5 2.2 3.6 1.4 2.4 1.8 2.3 20.2 2.3 3.1 1.0 13.1 3.8 3.4 7.0 1.6 2.3 1.7 2.2 1.5 2.6 2.4 2.3 2.9 2.7 7.4 1.4 1.2 1.9 1.2 3.6 3.6 1.7 4.1 1.8 1.1 1.2 2.2 1.3 2.7 4.2 1.8 2.0 4.1 2.6 2.7 1.6 0.0 1.0 0.5 2.5 1.2 3.2 1.9 1.9 1.9 1.2 3.2 2.0 3.4 0.0 1.1 1.0 2.0 1.9 1.0 11.4 12.1 6.6 11.0 12.2 2.9 7.2 7.3 5.6 7.2 GPAT2 CT123 ENSG00000186281 "Glycerol-3-phosphate acyltransferase 2, mitochondrial" Q6NUI2 2 96021946-96039451 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 7.3;BJ hTERT+ SV40 Large T+: 18.0;BJ hTERT+ SV40 Large T+ RasG12V: 10.7;HBF TERT88: 4.1;U-2 OS: 10.3" "Low cancer specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" HPA036841 Uncertain Approved Mitochondria Mitochondria "HPA036841: AB_10601479" "unprognostic (1.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.69e-2)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.38e-3)" "unprognostic (4.99e-2)" "unprognostic (3.28e-2)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (5.96e-2)" "unprognostic (4.67e-2)" "unprognostic (7.43e-6)" "unprognostic (2.11e-1)" "unprognostic (7.68e-2)" "unprognostic (3.49e-1)" "unprognostic (3.65e-1)" 4.3 1.1 1.5 1.9 3.1 1.5 3.6 0.2 1.6 0.8 1.0 0.0 1.1 5.1 0.9 1.0 2.2 3.9 1.1 0.7 0.5 0.5 1.3 3.2 1.2 0.9 1.1 0.0 0.2 2.0 0.6 1.5 1.8 4.9 1.4 0.5 1.3 2.4 2.3 4.4 3.0 7.3 1.2 2.6 2.6 0.8 4.3 1.1 0.5 2.5 0.2 3.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.3 0.0 18.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.4 0.0 2.6 0.0 0.0 0.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 2.6 1.9 2.8 4.3 1.3 2.0 1.1 4.1 0.8 3.0 0.0 0.2 2.5 0.0 1.3 1.5 GPAT3 "AGPAT10, AGPAT9, HMFN0839, LPAAT-theta, MAG1, MGC11324" ENSG00000138678 "Glycerol-3-phosphate acyltransferase 3" Q53EU6 4 83535914-83605875 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.2;kidney: 43.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 54.5;HMC-1: 20.0;U-87 MG: 23.8;WM-115: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 42.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA029414, CAB033749" Approved Uncertain "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB033749: AB_2224941, HPA029414: AB_10601562" "unprognostic (9.51e-2)" "unprognostic (1.43e-2)" "unprognostic (5.67e-2)" "unprognostic (1.70e-1)" "unprognostic (3.50e-3)" "unprognostic (2.61e-2)" "unprognostic (2.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (2.92e-1)" "prognostic favourable (2.71e-9)" "unprognostic (3.74e-1)" "unprognostic (3.45e-2)" "unprognostic (2.53e-3)" "prognostic unfavourable (8.21e-4)" 7.9 0.7 0.7 5.2 1.4 5.2 17.5 4.2 2.9 3.7 18.0 1.2 1.3 20.2 3.0 2.1 5.1 2.1 6.0 24.8 1.2 2.2 43.7 9.0 3.2 4.5 1.9 0.8 12.9 1.7 11.8 5.8 1.2 9.5 2.6 5.7 1.3 3.6 1.9 35.9 1.9 47.2 3.7 3.0 4.3 7.4 4.6 1.4 0.9 26.6 14.6 3.4 4.5 7.2 0.0 23.2 42.0 9.7 0.5 1.8 2.9 10.4 10.3 0.0 0.1 0.5 1.3 0.2 0.8 1.5 0.2 0.2 0.7 54.5 0.0 1.1 2.0 2.3 4.9 0.9 0.1 0.7 2.3 0.0 3.2 10.0 1.4 2.9 20.0 0.7 0.0 0.4 1.2 5.1 8.3 8.2 0.2 1.0 0.7 0.7 0.2 4.4 0.1 2.3 3.9 10.3 0.7 0.2 0.0 2.0 2.1 5.7 0.4 0.5 0.2 2.5 4.4 2.4 9.8 0.4 0.7 0.0 23.8 5.9 18.2 42.0 9.7 1.0 0.2 7.7 1.8 0.0 1.0 0.6 23.2 0.0 0.7 0.3 26.4 0.5 6.1 0.1 0.6 2.9 0.7 1.4 4.2 2.9 1.2 2.2 1.9 0.8 9.5 1.4 GPAT4 "AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7" ENSG00000158669 "Glycerol-3-phosphate acyltransferase 4" Q86UL3 8 41577187-41625001 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016471 Approved "HPA016471: AB_1844649" "unprognostic (3.05e-2)" "unprognostic (4.05e-2)" "unprognostic (4.24e-2)" "prognostic unfavourable (9.37e-4)" "unprognostic (7.45e-2)" "unprognostic (2.99e-3)" "unprognostic (5.08e-2)" "unprognostic (5.11e-2)" "unprognostic (3.79e-2)" "prognostic unfavourable (2.20e-4)" "unprognostic (1.98e-2)" "prognostic favourable (4.15e-4)" "unprognostic (1.73e-3)" "unprognostic (3.16e-2)" "unprognostic (3.35e-1)" "unprognostic (2.04e-2)" "prognostic favourable (5.65e-4)" 15.7 27.4 14.4 17.8 17.2 16.6 28.1 43.8 21.9 16.9 14.0 23.1 22.7 13.0 22.8 12.0 13.1 14.6 15.8 14.1 14.0 13.1 20.8 26.7 18.7 13.8 18.5 13.6 16.6 17.3 35.7 22.3 23.3 20.5 15.1 15.1 21.0 20.8 15.5 42.1 14.5 14.6 23.0 18.0 17.5 17.8 15.5 16.6 15.2 14.5 12.4 19.4 16.6 14.9 9.1 18.9 10.8 15.0 4.9 12.1 11.1 14.6 16.3 19.5 15.2 21.4 26.0 17.2 31.9 27.5 24.2 25.3 10.9 29.5 20.4 22.4 26.3 8.5 22.8 14.4 31.4 21.8 12.5 23.8 18.1 10.0 12.5 2.5 34.4 16.3 10.6 25.2 9.1 24.8 17.7 24.1 24.8 6.2 22.2 6.5 20.8 8.7 13.0 19.5 11.0 14.7 22.0 12.8 17.7 12.4 17.1 34.2 23.7 16.1 18.1 25.1 17.6 28.7 23.8 13.0 17.4 22.3 20.6 14.1 24.5 10.8 15.0 6.6 12.1 14.3 11.3 8.3 9.3 11.9 18.9 9.1 8.5 8.2 3.5 4.9 12.0 7.1 8.7 11.1 14.4 17.2 43.8 21.9 14.0 13.1 18.5 13.6 20.5 16.6 GPCPD1 "GDE5, GDPD6, KIAA1434" ENSG00000125772 "Glycerophosphocholine phosphodiesterase 1" Q9NPB8 20 5544404-5611026 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042987 Approved Nucleoplasm Nucleoplasm "HPA042987: " "unprognostic (2.25e-2)" "unprognostic (2.45e-2)" "unprognostic (3.41e-1)" "prognostic favourable (1.30e-4)" "unprognostic (2.93e-2)" "unprognostic (8.10e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-2)" "unprognostic (3.76e-2)" "unprognostic (1.67e-1)" "unprognostic (1.46e-1)" "unprognostic (1.18e-1)" "prognostic unfavourable (3.73e-4)" "unprognostic (1.56e-1)" "unprognostic (1.22e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-2)" 12.9 12.9 10.6 21.8 17.6 56.7 12.7 29.6 28.2 12.2 8.8 9.1 36.7 7.4 12.5 10.5 10.6 12.6 13.2 12.6 12.2 10.1 8.1 8.1 43.6 30.6 13.1 8.9 18.1 8.9 4.5 10.3 13.4 19.4 9.6 10.6 11.0 34.2 31.2 31.8 9.1 15.1 21.5 14.6 24.9 8.8 8.1 4.0 12.1 13.4 17.0 17.5 13.7 9.8 4.2 4.5 16.2 7.1 3.6 4.6 3.4 3.7 7.2 4.9 3.9 3.2 3.8 5.5 5.9 4.8 3.5 2.3 3.7 2.9 8.4 1.1 3.3 1.3 6.1 11.8 3.4 1.8 1.9 11.5 0.8 4.3 15.7 7.1 5.3 8.1 15.4 2.1 25.5 3.6 6.6 4.4 3.1 2.0 6.4 3.8 2.6 4.1 4.6 5.8 3.0 4.7 3.2 1.8 2.4 2.6 11.7 5.6 2.8 19.9 4.1 2.9 2.2 8.0 3.8 4.2 7.2 9.0 0.9 8.7 3.2 2.6 7.1 9.0 4.0 5.5 3.1 4.2 3.0 3.3 4.5 3.8 4.6 3.1 16.2 3.6 5.5 2.0 2.4 3.4 10.6 17.6 29.6 28.2 12.2 10.1 13.1 8.9 19.4 4.0 GPD1 ENSG00000167588 "Glycerol-3-phosphate dehydrogenase 1" P21695 12 50103819-50111319 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.3;skeletal muscle: 106.9" "Cell line enriched" "Detected in some" 4 "ASC diff: 52.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044620 Enhanced 3800000 "HPA044620: AB_10796803" "unprognostic (2.65e-2)" "unprognostic (5.60e-2)" "unprognostic (3.28e-2)" "unprognostic (3.37e-2)" "unprognostic (3.26e-1)" "unprognostic (2.54e-1)" "unprognostic (1.45e-3)" "unprognostic (7.19e-2)" "unprognostic (9.42e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (3.24e-1)" "unprognostic (1.37e-1)" "unprognostic (9.58e-2)" "unprognostic (3.37e-1)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" 116.3 1.2 2.4 3.6 3.0 0.3 44.9 1.6 3.9 0.3 13.4 12.2 0.4 16.2 0.3 3.0 1.2 0.3 8.1 3.9 4.3 2.7 30.6 31.4 4.0 1.6 6.8 1.2 0.2 1.8 2.3 0.3 0.2 13.5 0.5 0.9 0.1 17.7 0.5 106.9 2.0 23.5 0.5 24.7 0.2 0.8 0.3 2.0 0.0 0.7 14.1 0.3 1.1 0.3 0.7 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 52.2 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 9.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.6 0.1 0.0 0.2 0.0 0.0 0.6 0.3 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.4 3.0 1.6 3.9 4.3 2.7 6.8 1.2 13.5 2.0 GPD2 ENSG00000115159 "Glycerol-3-phosphate dehydrogenase 2" P43304 2 156435290-156613735 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.5;eosinophil: 3.1;intermediate monocyte: 3.3;myeloid DC: 5.1;neutrophil: 2.3;non-classical monocyte: 4.3" "Group enriched" "Detected in many" 5 "dendritic cells: 5.1;granulocytes: 3.1;monocytes: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008012, HPA045506" Enhanced "Intracellular and membrane" 7600000 "HPA008012: AB_1079013, HPA045506: AB_2679355" "unprognostic (1.30e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (4.79e-3)" "unprognostic (3.25e-1)" "unprognostic (2.39e-2)" "prognostic unfavourable (1.44e-4)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (2.60e-3)" "unprognostic (6.67e-2)" "unprognostic (6.02e-3)" "unprognostic (1.73e-1)" "unprognostic (1.89e-1)" "unprognostic (2.41e-1)" "unprognostic (1.01e-2)" 12.7 5.5 19.6 12.4 21.4 11.4 15.2 23.1 16.3 10.9 17.6 8.8 8.1 13.7 9.1 5.0 23.1 18.4 8.6 6.2 18.7 12.7 7.7 3.4 11.4 9.0 11.3 11.8 9.0 7.4 26.6 11.0 7.9 10.3 10.8 17.8 6.8 21.5 7.5 21.2 12.0 24.9 5.9 9.4 10.6 17.1 9.5 8.3 6.7 11.8 17.6 14.0 10.1 10.5 0.5 5.1 3.1 6.5 0.7 0.9 2.7 17.2 11.1 7.0 10.5 14.7 18.7 0.0 22.2 13.6 14.2 17.1 21.9 15.8 3.1 14.4 11.5 19.9 12.8 19.8 18.2 10.7 4.5 2.5 20.3 0.0 5.1 4.7 5.8 8.9 6.3 24.5 12.2 10.8 5.4 0.8 17.8 10.2 0.1 0.4 12.6 14.7 5.4 4.4 4.0 16.6 21.7 12.4 4.4 19.8 14.8 13.0 5.0 12.5 10.4 2.7 11.8 12.1 15.6 0.6 0.1 0.1 15.3 1.3 21.2 0.6 6.5 3.1 0.5 3.3 0.9 0.3 0.3 0.9 5.1 0.5 0.7 0.5 2.3 0.7 4.3 0.5 0.9 2.7 19.6 21.4 23.1 16.3 18.7 12.7 11.3 11.8 10.3 8.3 GPHN KIAA1385 ENSG00000171723 Gephyrin Q9NQX3 14 66507407-67181803 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" "Multifunctional enzyme, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003116, CAB004419, HPA024694" Enhanced Uncertain "Cytoplasmic bodies" "Cytoplasmic bodies" "CAB004419: AB_627670, HPA003116: AB_1078963, HPA024694: AB_1849616" "unprognostic (8.37e-2)" "unprognostic (2.53e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.14e-2)" "unprognostic (4.89e-3)" "unprognostic (8.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (2.49e-2)" "unprognostic (8.54e-2)" "prognostic favourable (5.25e-12)" "unprognostic (9.81e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "prognostic unfavourable (4.61e-5)" 13.0 12.4 26.1 10.9 31.1 5.2 17.1 40.9 31.2 11.0 18.2 9.3 15.6 11.1 12.3 20.8 8.6 7.5 8.2 11.9 26.4 22.9 34.5 49.0 14.1 7.3 18.3 11.5 7.2 22.9 17.4 24.5 5.8 13.9 11.1 13.2 7.4 10.8 21.3 23.4 10.7 10.8 11.6 16.4 5.6 13.5 7.8 16.2 3.1 12.2 10.0 6.8 7.4 15.1 3.1 3.0 0.5 2.5 2.3 6.2 1.5 22.3 4.4 7.8 8.6 9.3 7.9 5.0 6.4 3.1 6.5 6.6 1.3 10.1 0.0 1.1 3.1 7.9 7.8 12.4 8.6 6.8 8.5 6.6 6.3 13.6 4.8 3.7 9.9 6.7 7.3 1.8 7.2 7.6 4.5 8.5 3.6 11.9 6.6 14.0 3.3 10.2 0.0 15.1 6.5 10.5 4.4 13.9 5.4 4.3 19.0 7.0 10.2 6.4 2.8 6.6 14.6 6.4 6.5 11.3 4.8 0.1 5.2 0.5 6.3 0.0 1.3 0.5 3.9 2.5 6.2 2.4 4.9 2.9 1.9 3.1 3.5 3.3 0.0 2.3 1.9 3.0 5.3 1.5 26.1 31.1 40.9 27.0 26.4 22.9 18.3 11.5 13.9 16.2 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" 140000000 "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 62.1 66.6 43.4 27.6 58.2 83.3 34.8 62.6 88.7 20.6 36.6 20.8 23.7 48.2 21.1 20.6 45.3 24.2 33.5 107.2 42.0 45.6 51.3 77.9 19.6 29.6 39.3 64.3 22.5 21.4 66.9 33.7 20.4 50.2 23.7 37.2 36.2 34.6 33.9 144.7 29.4 44.3 34.2 22.8 23.1 26.7 19.7 19.0 23.8 26.1 68.5 32.6 32.5 25.2 16.2 26.3 74.8 40.9 14.5 27.5 24.6 76.1 107.4 9.4 73.5 30.9 23.0 22.5 29.4 23.2 37.1 44.8 60.5 27.0 50.2 43.7 28.8 53.1 56.8 63.9 42.2 55.8 22.9 64.5 51.8 63.6 20.0 83.5 42.0 31.5 26.4 43.9 22.8 34.6 32.8 39.8 26.1 64.6 36.3 29.2 25.4 38.0 34.0 24.9 94.8 46.5 51.3 51.4 29.9 59.3 104.6 21.4 23.7 26.6 29.8 14.0 30.9 39.8 45.3 73.5 41.7 45.5 46.8 63.5 28.4 38.5 22.9 74.8 22.5 35.2 27.5 16.2 20.7 25.5 26.3 13.3 17.5 20.7 1.6 14.5 40.9 8.7 21.6 24.6 43.4 58.2 62.6 88.7 42.0 45.6 39.3 64.3 50.2 19.0 GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 61.6" "Cell line enhanced" "Detected in many" "Daudi: 10.2;U-698: 10.4" "Cancer enriched" "Detected in some" 11 "liver cancer: 6.8" "Region enriched" "Detected in many" 4 "cerebellum: 8.5" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" 102626666667 3700000000 "CAB008625: AB_1621070, HPA012500: AB_1849931" "unprognostic (6.80e-3)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (4.81e-5)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "prognostic favourable (1.12e-4)" "unprognostic (6.37e-4)" "unprognostic (7.93e-2)" "unprognostic (2.86e-2)" "unprognostic (6.07e-4)" "unprognostic (2.68e-1)" "unprognostic (5.28e-4)" "unprognostic (2.20e-1)" "unprognostic (9.98e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" 2.2 0.4 0.8 0.6 1.2 0.3 0.6 8.5 1.8 0.6 0.6 0.6 0.6 0.1 0.8 0.6 0.6 0.4 0.6 0.6 0.6 1.9 0.6 61.6 0.6 0.6 0.7 0.6 0.7 0.6 1.5 1.3 0.6 0.6 1.0 0.1 0.6 0.6 3.3 0.7 4.8 0.6 0.8 0.6 0.6 0.3 0.8 0.6 6.6 1.6 0.6 0.7 1.0 1.0 1.1 1.6 0.4 0.2 0.1 1.8 0.0 0.7 1.3 1.2 1.8 0.0 0.1 3.0 0.1 0.3 0.4 0.3 5.2 0.1 10.2 1.2 0.2 0.0 1.7 0.3 0.2 1.3 3.4 1.4 1.3 4.3 0.0 1.8 0.2 0.1 0.2 0.1 0.0 0.0 0.6 0.5 0.3 0.7 1.0 0.6 3.9 0.5 2.0 0.3 0.1 0.4 5.1 3.3 3.4 1.1 0.1 0.5 0.5 0.5 0.1 1.2 1.3 0.1 1.4 3.0 4.7 10.4 0.1 0.5 0.5 0.4 0.2 0.1 0.4 0.1 1.4 0.6 0.3 0.2 0.0 1.1 0.3 1.8 0.4 0.1 0.1 1.6 0.2 0.0 0.8 1.2 8.5 1.8 0.6 1.9 0.7 0.6 0.6 0.6 GPT "ALT1, GPT1" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 56.8;skeletal muscle: 27.0" "Cell line enhanced" "Detected in many" "Hep G2: 4.7;Karpas-707: 5.6;U-266/70: 6.0" "Cancer enriched" "Detected in many" 7 "liver cancer: 38.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "intermediate monocyte: 2.3;non-classical monocyte: 2.9" "Lineage enriched" "Detected in single" 6 "monocytes: 2.9" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced 15000000 "CAB032997: AB_2261949, CAB032999: AB_2095427, HPA031059: AB_10600214, HPA031060: AB_10602178" "unprognostic (8.22e-3)" "unprognostic (2.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-2)" "prognostic favourable (1.47e-5)" "unprognostic (9.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.41e-1)" "unprognostic (9.22e-2)" "prognostic favourable (2.19e-4)" "unprognostic (2.83e-2)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" 9.0 0.8 1.7 8.7 2.2 1.1 3.9 1.5 2.3 0.2 17.4 2.0 4.6 10.9 0.2 1.7 0.9 0.5 19.8 16.9 1.7 0.9 8.7 56.8 0.2 0.2 1.3 2.2 0.4 3.6 0.5 1.1 0.1 2.0 0.7 3.5 1.6 17.0 2.7 27.0 6.1 19.2 0.2 0.7 0.4 8.6 0.8 1.6 0.0 0.6 13.9 3.3 0.3 0.5 0.0 0.5 0.0 2.9 0.0 0.0 0.0 0.5 1.5 0.4 1.1 0.9 0.0 1.3 0.8 0.0 0.0 0.0 0.4 1.9 0.8 0.7 0.0 4.3 0.0 0.0 0.0 1.5 2.7 0.7 2.5 4.7 0.0 0.1 0.8 0.0 0.4 0.0 0.0 0.0 0.5 5.6 0.0 2.6 0.9 0.9 0.6 1.0 0.9 0.3 3.0 0.0 1.8 1.2 1.7 0.5 1.4 0.2 3.8 0.2 0.4 0.3 1.3 1.3 0.2 6.0 0.4 0.4 0.8 1.9 0.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 1.7 2.2 1.5 2.3 1.7 0.9 1.3 2.2 2.0 1.6 GPT2 ALT2 ENSG00000166123 "Glutamic--pyruvic transaminase 2" Q8TD30 16 46884378-46931297 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 103.0;skeletal muscle: 60.9" "Cell line enhanced" "Detected in many" "Hep G2: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 4.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051514 Approved Approved Mitochondria Mitochondria "HPA051514: " "unprognostic (1.65e-2)" "unprognostic (3.32e-2)" "unprognostic (2.87e-1)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (1.27e-1)" "unprognostic (1.95e-3)" "unprognostic (3.44e-2)" "unprognostic (6.12e-2)" "prognostic favourable (3.17e-4)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.44e-2)" "unprognostic (4.86e-1)" "unprognostic (3.54e-3)" "unprognostic (3.18e-1)" 19.9 4.1 20.2 2.1 17.8 1.9 6.4 3.9 15.1 2.5 3.4 11.8 10.0 1.3 2.1 13.4 30.8 3.7 4.4 3.0 13.4 8.0 9.8 40.4 1.4 2.1 12.9 7.8 1.5 103.0 4.3 4.3 1.8 11.3 10.2 2.6 1.5 27.6 8.5 60.9 14.9 1.7 1.9 11.3 1.4 15.4 6.0 12.3 0.7 3.6 19.0 14.6 1.9 2.1 4.2 1.4 1.3 0.7 0.0 0.4 0.4 12.9 5.9 7.5 28.5 10.6 2.3 13.7 9.0 3.4 9.7 6.2 20.1 5.5 9.1 7.9 6.4 10.4 13.5 13.3 6.5 4.2 6.6 3.2 3.4 48.5 7.3 22.7 3.0 4.9 11.7 9.5 14.8 4.7 2.6 7.3 3.2 23.1 4.5 19.0 7.9 17.0 0.1 8.3 21.1 3.9 6.4 23.5 12.0 4.6 24.1 12.2 6.2 20.8 3.5 6.8 13.3 4.5 7.2 35.1 10.6 25.7 10.4 14.8 3.6 1.3 0.7 0.0 0.3 0.0 0.0 4.2 0.0 0.3 1.4 2.5 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.4 20.2 17.8 3.9 15.1 13.4 8.0 12.9 7.8 11.3 12.3 GPX2 GSHPX-GI ENSG00000176153 "Glutathione peroxidase 2" P18283 14 64939152-64942905 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 126.9;liver: 195.2" "Group enriched" "Detected in some" 20 "A549: 120.7;HaCaT: 33.4;Hep G2: 112.0;RT4: 79.8;SCLC-21H: 36.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "NK-cell: 2.4" "Low lineage specificity" "Detected in single" "Region enhanced" "Detected in single" "pons and medulla: 1.3" "Low region specificity" "Detected in single" HPA003545 Enhanced Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA003545: AB_10962695" "unprognostic (3.54e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.90e-3)" "unprognostic (4.75e-3)" "prognostic unfavourable (5.10e-4)" "unprognostic (2.96e-2)" "unprognostic (2.93e-2)" "unprognostic (7.87e-2)" "unprognostic (1.54e-2)" "unprognostic (8.45e-2)" "unprognostic (1.44e-1)" "unprognostic (2.77e-2)" "unprognostic (4.39e-2)" "unprognostic (3.39e-2)" "unprognostic (6.66e-4)" "unprognostic (1.73e-2)" 0.1 0.0 0.1 23.8 0.2 0.0 0.8 0.2 0.1 5.5 50.4 0.5 2.0 14.4 0.3 1.0 53.0 0.6 126.9 0.2 0.1 0.2 29.4 195.2 2.0 0.1 0.1 0.1 0.9 7.0 0.0 0.2 0.1 0.2 16.8 71.6 0.1 59.7 4.1 0.3 3.9 35.4 5.6 0.2 0.1 57.8 0.4 0.1 0.5 0.2 44.0 7.4 56.3 15.0 0.2 0.0 0.5 0.8 2.4 0.1 0.0 0.0 120.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 1.0 0.0 0.7 0.0 33.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 112.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 79.8 36.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.5 2.4 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 GPX3 ENSG00000211445 "Glutathione peroxidase 3" P22352 5 151020438-151028993 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 844.2;thyroid gland: 424.1" "Cell line enriched" "Detected in some" 12 "ASC diff: 417.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 856.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "neutrophil: 16.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 16.7" "Region enhanced" "Detected in many" "hypothalamus: 279.6" "Group enriched" "Detected in many" 4 "basal ganglia: 67.2;hypothalamus: 176.5;midbrain: 58.6;pons and medulla: 52.3" CAB069456 Approved "Secreted to blood" 5092600000 10000000000 "CAB069456: AB_1616682" "unprognostic (4.03e-1)" "unprognostic (7.35e-2)" "unprognostic (5.05e-3)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "unprognostic (8.13e-2)" "unprognostic (1.39e-2)" "unprognostic (1.62e-1)" "unprognostic (5.75e-3)" "unprognostic (2.70e-3)" "unprognostic (8.17e-3)" "unprognostic (1.14e-2)" "unprognostic (2.95e-1)" "prognostic unfavourable (1.65e-4)" "unprognostic (2.14e-1)" "unprognostic (5.11e-2)" "unprognostic (1.26e-1)" 177.5 21.9 1.2 6.6 5.5 1.6 310.9 3.1 6.3 26.2 33.9 5.1 6.5 7.5 11.8 16.8 44.4 27.0 17.3 108.1 2.7 5.0 844.2 64.1 88.2 43.8 3.9 1.8 28.8 13.0 5.5 32.3 44.8 17.6 41.3 8.3 160.8 14.8 12.4 56.7 18.7 18.5 48.5 3.5 29.6 19.5 23.6 1.2 0.5 424.1 19.0 9.8 58.8 164.2 0.0 3.5 16.7 3.6 0.0 0.2 1.2 0.1 0.5 0.4 0.1 417.4 0.3 0.4 0.1 0.0 0.4 0.1 8.9 0.2 0.0 11.4 0.2 0.1 2.0 22.5 0.3 0.3 0.1 0.0 0.2 9.7 16.0 0.0 0.2 35.3 2.1 0.0 0.0 0.5 0.0 0.0 0.5 1.5 0.0 0.0 0.7 0.0 0.0 0.2 0.0 3.9 0.2 0.6 0.6 0.0 1.6 0.1 2.2 0.1 0.1 0.1 1.0 0.1 0.0 0.1 0.7 0.1 0.3 0.1 0.0 0.0 3.6 0.1 0.0 1.4 0.2 0.0 0.0 0.0 3.5 0.0 0.0 0.0 16.7 0.0 0.1 0.0 0.0 1.2 1.2 5.5 3.1 3.6 2.7 5.0 3.9 1.8 17.6 1.2 GPX4 "MCSP, PHGPx" ENSG00000167468 "Glutathione peroxidase 4" P36969 19 1103926-1106791 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Oxidoreductase, Peroxidase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008630, HPA047224, HPA058546" Enhanced Supported Nucleoplasm,Mitochondria "Intracellular and membrane" 220000 "Nucleoplasm, Mitochondria" "CAB008630: AB_1616685, HPA047224: , HPA058546: " "unprognostic (8.42e-3)" "prognostic favourable (7.18e-4)" "unprognostic (8.14e-3)" "prognostic favourable (1.84e-5)" "unprognostic (1.00e-1)" "unprognostic (8.72e-2)" "unprognostic (2.53e-3)" "unprognostic (8.49e-2)" "unprognostic (2.69e-2)" "unprognostic (1.47e-1)" "prognostic favourable (7.72e-4)" "unprognostic (1.29e-1)" "prognostic favourable (8.61e-4)" "unprognostic (1.61e-2)" "unprognostic (2.20e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" 163.0 76.4 63.3 27.1 73.7 33.3 102.3 33.5 83.7 53.3 49.1 42.4 33.8 56.9 27.2 74.7 35.6 38.4 46.9 64.4 54.2 60.2 75.3 119.0 44.7 41.7 74.6 47.3 47.1 35.1 33.1 54.7 46.4 49.3 44.7 25.5 82.3 61.6 46.9 98.2 36.3 58.5 43.6 46.5 32.4 27.7 170.4 36.5 29.9 52.8 49.8 39.2 51.2 47.0 56.7 64.0 85.2 85.2 28.4 58.5 110.5 28.3 32.3 46.7 98.7 141.7 84.0 52.0 22.5 81.3 42.9 43.8 65.9 38.5 10.3 24.6 45.5 32.0 27.3 32.6 21.0 57.6 49.3 19.4 29.0 92.9 82.4 22.7 31.1 83.3 49.7 21.7 36.6 60.0 27.1 25.9 35.4 72.9 38.4 39.0 44.2 52.1 53.3 6.3 29.7 46.6 70.6 40.3 25.5 44.1 41.9 45.8 40.9 55.6 50.8 45.7 30.4 78.3 28.2 91.1 61.7 24.0 43.0 45.6 26.2 75.6 85.2 85.2 37.0 62.0 43.0 56.7 54.3 38.6 64.0 47.8 58.5 41.7 42.4 28.4 68.3 44.1 46.8 110.5 63.3 73.7 33.5 83.7 54.2 60.2 74.6 47.3 49.3 36.5 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160118-55167071 "Enzymes, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 51.7;fHDF/TERT166: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA036720 Enhanced Supported "Actin filaments,Cytosol" "Actin filaments, Cytosol" "HPA036720: " "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavourable (5.13e-9)" "prognostic unfavourable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 12.6 7.1 0.8 5.8 1.0 0.0 12.2 0.5 0.7 31.4 6.8 1.7 17.3 1.3 23.6 34.5 13.3 13.2 11.2 12.1 1.0 0.9 13.7 2.6 7.3 5.6 1.1 0.9 31.5 5.0 4.5 3.2 40.9 4.0 24.2 4.7 17.8 7.3 16.7 5.0 5.1 4.4 14.1 3.3 7.5 4.9 10.2 0.5 0.7 28.4 11.0 5.4 15.8 19.7 1.0 0.7 2.4 0.5 0.6 0.9 0.2 6.9 5.9 12.7 12.4 33.7 38.4 7.0 35.6 51.7 20.0 40.1 0.6 15.9 0.0 38.0 48.4 6.0 7.6 10.3 27.5 0.0 3.2 0.3 10.4 1.2 10.7 0.0 0.0 27.1 10.3 12.2 6.4 23.3 0.2 0.0 22.7 2.2 0.0 0.0 5.8 8.2 0.0 7.3 0.0 12.3 0.2 0.0 0.3 12.0 0.8 12.6 11.4 0.7 20.9 10.7 11.8 15.9 19.1 0.0 0.0 0.0 17.0 0.0 23.2 1.4 0.5 0.3 0.5 0.3 0.5 0.6 0.5 0.5 0.2 1.0 0.9 0.9 2.4 0.6 0.3 0.7 0.2 0.2 0.8 1.0 0.5 0.7 1.0 0.9 1.1 0.9 4.0 0.5 GRHPR "GLXR, PH2" ENSG00000137106 "Glyoxylate and hydroxypyruvate reductase" Q9UBQ7 9 37422666-37436990 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 172.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022971 Uncertain Approved Nucleoplasm,Cytosol 1400000 Cytosol Nucleoplasm "HPA022971: AB_1849975" "prognostic favourable (7.00e-5)" "unprognostic (6.84e-2)" "unprognostic (2.62e-1)" "unprognostic (2.64e-3)" "unprognostic (5.78e-3)" "unprognostic (3.04e-1)" "unprognostic (1.02e-3)" "unprognostic (1.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.49e-2)" "unprognostic (5.88e-2)" "unprognostic (2.36e-1)" "prognostic favourable (5.39e-9)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (1.79e-1)" 12.8 33.7 16.3 13.8 17.4 9.9 12.3 9.5 22.3 12.1 17.6 27.5 11.6 17.2 14.3 18.1 17.6 12.9 18.1 29.2 15.8 14.7 41.9 172.0 9.7 13.8 20.0 16.5 17.0 15.5 9.5 8.8 13.2 15.5 14.2 10.2 13.5 21.6 14.0 40.0 14.8 14.6 14.2 19.4 10.0 13.3 13.0 18.7 9.5 15.1 25.2 13.6 13.4 11.7 30.6 33.2 17.8 30.3 28.9 25.9 22.4 31.3 45.2 25.6 23.4 23.6 26.2 26.0 25.1 33.3 34.2 37.2 17.1 13.6 30.1 14.8 29.4 14.2 14.7 32.7 20.5 40.2 18.4 17.6 42.1 30.3 37.3 16.7 18.3 31.3 28.7 19.8 25.5 29.6 32.2 12.4 30.0 24.0 16.3 17.2 15.6 19.7 16.1 18.8 16.7 45.6 17.8 10.7 19.2 21.6 41.2 23.4 23.2 21.6 32.2 18.8 30.2 13.0 21.6 9.8 7.6 20.1 26.7 9.6 27.5 17.8 30.2 15.0 19.4 30.3 16.2 28.6 20.7 22.0 33.2 30.6 20.4 17.3 7.0 28.9 24.7 29.8 25.9 22.4 16.3 17.4 9.5 22.3 15.8 14.7 20.0 16.5 15.5 18.7 GRK1 "GPRK1, RHOK, RK" ENSG00000185974 "G protein-coupled receptor kinase 1" Q15835 13 113667155-113737735 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Congenital stationary night blindness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "retina: 51.5" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.2" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035200, HPA059376" Enhanced "HPA035200: AB_2674515, HPA059376: AB_2683996" "unprognostic (7.93e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-1)" "unprognostic (1.24e-5)" "unprognostic (1.76e-3)" "unprognostic (1.53e-1)" "unprognostic (3.59e-2)" "unprognostic (2.21e-2)" "unprognostic (1.84e-3)" "unprognostic (2.00e-2)" "unprognostic (4.02e-2)" "unprognostic (6.91e-2)" "unprognostic (6.18e-2)" "unprognostic (6.11e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 51.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 GRK2 "ADRBK1, BARK1" ENSG00000173020 "G protein-coupled receptor kinase 2" P25098 11 67266410-67286556 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 78.2" "Cell line enhanced" "Detected in all" "NB-4: 55.2;REH: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005021, CAB037248, HPA048330" Approved Approved Vesicles Vesicles "CAB005021: AB_562360, CAB037248: AB_1078280, HPA048330: " "unprognostic (5.58e-2)" "unprognostic (1.75e-1)" "unprognostic (2.01e-2)" "unprognostic (5.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.29e-3)" "unprognostic (3.31e-2)" "unprognostic (6.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-2)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" "prognostic unfavourable (1.25e-4)" "unprognostic (3.66e-1)" "unprognostic (2.40e-1)" "unprognostic (4.04e-2)" "unprognostic (5.19e-3)" 13.1 10.7 24.5 35.8 17.0 78.2 17.0 32.9 35.3 12.8 17.2 12.2 12.6 17.5 11.4 9.9 20.2 12.6 17.6 13.6 21.9 17.4 13.0 14.1 19.1 42.8 13.4 19.0 9.8 10.4 9.7 12.2 12.7 15.7 17.8 16.2 9.3 17.4 20.8 20.8 23.5 26.3 12.2 12.5 59.6 17.4 6.8 11.1 35.9 10.1 13.6 37.5 17.1 15.5 4.1 6.0 21.0 18.3 3.8 5.3 7.4 7.5 5.3 5.2 8.8 4.2 3.8 5.2 4.5 4.3 6.2 5.1 11.8 12.5 38.8 7.3 4.2 10.2 7.6 6.1 3.2 47.2 4.7 22.0 6.1 5.3 5.2 46.1 44.2 3.4 7.1 4.9 6.6 7.9 7.9 19.9 5.3 14.0 25.6 55.2 6.5 8.0 73.3 10.3 11.5 6.3 9.9 10.5 5.7 6.7 9.8 16.0 9.1 50.2 4.3 4.9 6.5 6.2 5.0 12.7 11.6 34.8 6.4 27.3 4.5 6.9 10.3 10.5 5.3 15.9 4.0 3.8 4.0 4.3 6.0 4.1 3.2 3.1 21.0 3.8 18.3 5.3 2.6 7.4 24.5 17.0 32.9 35.3 21.9 17.4 13.4 19.0 15.7 11.1 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564849-25729294 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 28.0" "Cell line enhanced" "Detected in many" "HDLM-2: 22.6;SH-SY5Y: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.8;eosinophil: 5.6;intermediate monocyte: 8.0;memory B-cell: 4.9;myeloid DC: 3.7;naive B-cell: 6.2;non-classical monocyte: 7.4;plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favourable (1.29e-4)" 28.0 6.0 11.9 12.4 10.8 7.0 11.3 7.9 18.9 4.7 4.0 3.1 0.7 3.0 5.7 3.1 2.7 9.1 5.0 4.6 15.7 8.3 3.0 3.4 9.4 14.1 9.7 9.8 4.1 8.4 4.4 8.2 4.5 9.6 8.2 4.3 4.8 3.7 1.9 1.4 4.1 6.1 6.2 4.9 23.2 4.0 14.8 2.7 11.6 4.5 1.3 15.2 6.7 2.5 6.2 3.7 5.6 8.0 0.0 0.4 1.6 0.0 2.1 6.5 2.1 4.5 0.6 9.4 0.7 2.0 2.0 3.5 3.4 3.7 11.8 0.2 0.1 0.1 6.4 4.8 6.1 22.6 4.2 5.4 0.7 7.4 0.2 17.5 9.2 1.1 3.3 1.4 2.5 0.3 0.5 0.0 2.4 2.9 12.5 1.2 4.6 0.0 5.6 10.3 2.0 0.0 3.5 15.1 20.5 1.1 0.0 4.9 1.8 7.0 0.2 0.0 13.3 0.1 2.5 1.4 4.6 9.2 8.7 6.2 2.0 0.6 4.8 5.6 0.0 8.0 0.3 4.9 0.0 0.3 3.7 6.2 0.1 0.2 0.3 0.0 7.4 3.2 0.4 1.6 11.9 10.8 7.9 18.9 15.7 8.3 9.7 9.8 9.6 2.7 GRK4 "GPRK2L, GPRK4" ENSG00000125388 "G protein-coupled receptor kinase 4" P32298 4 2963608-3040747 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028737, HPA057023" Approved Supported Vesicles Vesicles "HPA028737: , HPA057023: " "unprognostic (1.86e-2)" "unprognostic (2.88e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (3.65e-1)" "unprognostic (1.84e-1)" "unprognostic (1.21e-1)" "unprognostic (2.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.87e-1)" "unprognostic (3.90e-4)" "unprognostic (3.20e-1)" "unprognostic (1.01e-2)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.89e-1)" 3.4 3.6 5.4 1.6 5.1 1.7 4.8 12.5 5.9 3.0 2.1 4.2 1.0 1.5 2.7 3.1 2.4 2.0 3.0 5.6 5.2 4.8 2.8 2.3 2.4 1.6 5.3 5.3 3.4 7.9 3.9 6.2 2.2 5.9 2.4 2.0 3.1 4.0 2.9 5.0 2.9 1.7 2.8 5.4 1.9 2.5 41.2 3.7 1.6 4.1 1.6 1.7 2.5 3.3 1.2 2.5 4.5 2.0 1.6 1.7 1.0 2.4 0.9 3.0 8.5 7.3 7.0 1.8 4.8 2.1 2.7 2.4 2.4 0.8 5.5 2.1 7.6 0.8 3.9 4.0 2.4 3.8 3.9 6.0 3.4 2.8 4.3 2.4 2.2 4.7 6.2 4.8 2.3 5.1 5.6 7.2 6.4 2.8 5.1 5.1 2.3 6.7 6.5 3.8 2.2 2.6 3.1 17.3 5.3 2.9 1.3 4.3 6.5 3.7 5.9 7.4 1.9 5.0 4.2 7.4 4.2 4.2 3.7 5.3 2.5 4.5 1.1 2.1 1.1 2.0 1.4 1.1 0.7 0.7 0.3 1.2 1.7 1.6 4.0 1.6 0.7 2.5 0.4 1.0 5.4 5.1 12.5 5.9 5.2 4.8 5.3 5.3 5.9 3.7 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207589-119459742 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 36.5;HUVEC TERT2: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: " "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavourable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 15.9 8.3 3.4 16.8 7.8 2.7 10.2 6.5 5.0 12.5 18.8 3.9 4.5 12.4 13.4 12.2 8.1 7.7 19.5 45.4 4.2 4.2 4.3 5.7 27.6 8.8 3.7 2.5 16.5 3.5 26.2 6.3 24.0 4.5 7.5 6.4 5.6 5.0 6.7 12.8 4.7 10.4 10.8 4.8 17.0 13.9 3.5 4.7 9.8 8.9 10.7 8.6 9.5 13.6 9.3 2.2 6.5 3.7 0.2 11.3 4.2 4.0 2.3 6.0 6.1 13.8 13.3 1.8 7.8 36.5 4.9 2.7 1.9 5.9 4.3 1.8 12.2 1.0 2.6 8.6 3.2 17.1 2.1 0.7 5.0 7.7 9.5 0.2 2.2 1.8 1.3 9.8 1.4 28.8 0.4 4.2 1.7 0.6 4.0 3.9 0.9 6.0 1.4 0.8 1.0 0.8 1.6 2.0 5.5 2.7 1.2 7.5 0.1 1.0 8.7 2.6 1.9 15.8 3.0 0.9 4.6 2.6 5.5 4.8 2.5 0.9 3.7 6.5 5.3 3.2 0.4 9.3 7.7 3.8 2.2 9.1 11.3 5.0 5.0 0.2 0.9 0.0 9.2 4.2 3.4 7.8 6.5 5.0 4.2 4.2 3.7 2.5 4.5 4.7 GRK6 GPRK6 ENSG00000198055 "G protein-coupled receptor kinase 6" P43250 5 177403204-177442901 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015327, HPA018903" Approved Approved Mitochondria 7500 Mitochondria "HPA015327: AB_1850334, HPA018903: AB_1850335" "unprognostic (1.06e-1)" "unprognostic (3.39e-2)" "unprognostic (4.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavourable (5.66e-6)" "unprognostic (2.63e-1)" "unprognostic (6.45e-2)" "unprognostic (8.96e-2)" "prognostic favourable (1.22e-4)" "unprognostic (1.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.83e-3)" "unprognostic (1.15e-1)" "unprognostic (4.00e-2)" "unprognostic (3.47e-1)" 6.8 5.5 7.8 26.8 7.3 68.1 10.2 7.7 10.9 5.9 9.2 6.6 5.0 10.9 8.0 6.0 11.0 6.6 9.3 6.2 8.0 7.3 5.7 6.6 11.1 37.6 7.1 10.7 6.1 12.1 3.5 5.6 4.9 6.7 8.1 5.5 5.0 10.8 5.2 7.4 7.7 14.5 7.8 5.4 34.3 9.1 10.5 5.1 32.3 5.3 6.4 26.5 11.4 6.5 9.2 5.7 32.1 22.6 17.4 11.7 9.1 12.1 13.2 4.8 21.1 1.4 2.4 20.7 8.9 4.7 11.3 11.2 30.8 10.4 14.4 13.7 4.7 8.9 7.5 20.4 4.4 39.6 23.4 12.8 10.8 10.4 7.8 17.2 16.3 3.8 5.1 11.2 6.6 6.3 13.3 52.2 3.4 34.7 17.7 18.0 8.3 14.6 17.0 7.8 20.8 3.3 9.9 11.2 15.2 7.4 13.1 17.2 10.3 19.0 8.0 9.1 13.8 9.7 22.3 15.1 18.2 11.7 6.2 28.2 8.9 4.5 9.5 32.1 11.7 16.5 8.4 9.2 9.8 10.7 5.5 9.2 10.4 9.0 23.2 17.4 22.6 5.7 11.7 9.1 7.8 7.3 7.7 10.9 8.0 7.3 7.1 10.7 6.7 5.1 GSK3A ENSG00000105723 "Glycogen synthase kinase 3 alpha" P49840 19 42230186-42242625 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004422, HPA028423" Approved Approved Cytosol Cytosol "CAB004422: AB_627680, HPA028423: AB_10612116" "unprognostic (5.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "prognostic unfavourable (4.02e-4)" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "prognostic unfavourable (1.13e-4)" "unprognostic (3.80e-3)" "unprognostic (2.27e-1)" "unprognostic (2.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.36e-1)" "unprognostic (2.69e-1)" "unprognostic (2.77e-2)" "unprognostic (4.49e-2)" "unprognostic (7.22e-2)" "unprognostic (8.22e-3)" 15.3 19.8 31.0 16.8 38.0 14.4 12.0 31.4 62.2 15.9 16.8 24.3 11.4 28.6 16.9 18.0 17.3 16.7 11.8 21.3 31.3 23.6 17.5 13.1 14.2 15.0 21.8 26.3 20.0 19.3 16.1 14.2 14.7 31.7 15.8 16.1 15.5 18.1 20.3 41.0 25.1 27.0 18.5 18.0 14.5 14.7 19.1 17.7 16.6 15.8 11.9 15.8 15.8 15.5 1.6 2.2 4.0 1.9 1.7 2.0 1.0 23.6 42.0 24.1 22.3 14.4 12.9 10.2 16.7 15.9 22.1 20.0 15.7 15.1 17.1 17.2 13.1 10.9 19.8 19.4 15.5 13.8 31.8 17.8 13.5 15.5 19.0 20.2 21.8 12.6 20.6 18.1 20.7 20.0 29.9 25.6 18.9 28.7 26.2 17.9 17.8 17.4 23.9 14.0 13.2 20.4 24.8 28.1 28.4 22.9 30.0 15.2 17.3 26.8 17.7 22.8 17.1 13.2 29.5 26.2 30.0 13.4 26.5 20.4 25.0 2.5 1.5 1.6 2.0 1.9 1.4 1.2 1.2 1.3 1.4 1.6 0.7 1.5 4.0 1.7 1.1 2.2 1.0 1.0 31.0 38.0 31.4 62.2 31.3 23.6 21.8 26.3 31.7 17.7 GSK3B ENSG00000082701 "Glycogen synthase kinase 3 beta" P49841 3 119821323-120094417 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Differentiation, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016263, HPA028017" Approved Supported Nucleoplasm 81000 Nucleoplasm "CAB016263: AB_2279451, HPA028017: AB_10600708" "unprognostic (1.09e-2)" "unprognostic (2.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-3)" "unprognostic (1.15e-1)" "unprognostic (4.86e-2)" "prognostic unfavourable (8.20e-5)" "unprognostic (3.39e-2)" "unprognostic (1.11e-1)" "unprognostic (1.67e-2)" "unprognostic (1.05e-3)" "unprognostic (6.79e-2)" "prognostic favourable (1.52e-4)" "unprognostic (2.39e-1)" "unprognostic (2.58e-1)" "unprognostic (1.28e-2)" "unprognostic (1.16e-1)" 17.6 17.6 17.4 13.8 21.3 25.0 13.7 32.7 28.3 15.8 16.0 15.6 7.1 15.5 14.5 12.6 20.3 12.4 14.4 20.8 17.1 22.4 15.7 21.7 17.1 17.5 17.0 22.6 14.0 14.9 25.0 19.2 24.1 18.1 13.9 17.9 14.9 18.5 11.7 23.9 21.6 18.2 17.1 13.4 26.3 13.3 30.8 14.4 46.5 17.4 8.4 14.1 14.2 15.7 1.7 2.0 10.6 3.1 1.4 3.0 1.0 28.3 13.7 23.0 13.3 15.3 15.6 22.3 16.0 30.8 15.4 14.1 14.8 11.6 11.5 9.8 22.8 19.4 10.8 31.1 23.9 7.8 3.0 16.8 10.3 11.0 17.5 17.2 22.5 15.7 20.9 16.4 33.5 16.9 7.1 22.4 20.1 15.3 18.3 4.8 12.5 14.2 7.3 19.6 11.1 11.2 20.3 17.3 10.7 18.8 13.7 18.5 17.0 11.6 21.6 22.1 24.9 6.9 9.5 14.9 13.7 22.2 13.7 11.5 17.6 4.3 2.9 7.5 2.4 2.6 2.1 1.1 2.0 3.0 2.0 1.7 2.0 1.5 10.6 1.4 3.1 1.6 1.3 1.0 17.4 21.3 32.7 28.3 17.1 22.4 17.0 22.6 18.1 14.4 GSR ENSG00000104687 "Glutathione-disulfide reductase" P00390 8 30678061-30727999 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001538, CAB008632" Approved Supported "Plasma membrane,Cytosol" 110000000 Cytosol "Plasma membrane" "CAB008632: AB_1616690, HPA001538: AB_1078986" "unprognostic (1.23e-1)" "prognostic favourable (3.37e-4)" "prognostic favourable (4.08e-5)" "unprognostic (2.89e-3)" "unprognostic (1.62e-1)" "unprognostic (3.50e-1)" "prognostic unfavourable (3.26e-5)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (4.15e-2)" "unprognostic (2.83e-2)" "unprognostic (6.92e-3)" "prognostic favourable (1.80e-4)" "unprognostic (2.31e-3)" "unprognostic (2.26e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" 8.9 14.4 6.8 10.7 9.1 7.9 6.2 9.1 11.8 18.6 18.7 7.1 18.4 20.4 13.2 12.0 19.4 8.8 17.3 11.9 5.0 5.7 27.9 17.8 10.8 9.7 4.9 6.0 11.8 17.6 22.9 7.2 8.9 6.8 16.4 17.2 10.9 12.0 17.4 14.7 6.5 31.8 9.3 4.5 13.6 17.7 7.9 4.2 17.0 9.2 11.8 12.0 23.9 14.5 2.5 4.7 19.0 5.7 2.6 7.3 2.1 12.0 51.0 8.3 6.4 8.9 10.0 8.0 5.4 11.8 7.7 10.3 15.0 6.4 23.6 26.7 6.9 13.6 12.5 11.7 8.4 6.1 11.6 23.7 17.6 50.1 24.0 7.2 38.3 16.6 7.4 11.5 4.6 10.9 19.6 10.5 17.3 11.0 25.5 8.5 14.7 9.1 9.8 9.5 11.4 15.2 30.6 6.3 8.1 7.4 17.3 12.9 7.5 8.2 14.7 3.2 8.9 7.6 8.0 5.8 6.4 15.1 10.2 10.2 10.5 19.0 4.6 11.5 4.2 4.2 7.3 2.5 3.8 4.6 4.7 2.0 2.4 3.1 6.5 2.6 5.7 2.9 3.2 2.1 6.8 9.1 9.1 11.8 5.0 5.7 4.9 6.0 6.8 4.2 GSS ENSG00000100983 "Glutathione synthetase" P48637 20 34928433-34956027 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease mutation, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054508, HPA059315" Enhanced Supported Nucleoplasm 23000000 Nucleoplasm "HPA054508: AB_2682509, HPA059315: AB_2683976" "unprognostic (5.80e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (7.21e-2)" "unprognostic (3.63e-2)" "unprognostic (5.68e-2)" "prognostic unfavourable (7.21e-5)" "unprognostic (2.90e-2)" "unprognostic (8.52e-2)" "unprognostic (3.64e-1)" "unprognostic (6.49e-2)" "unprognostic (1.50e-1)" "prognostic favourable (7.31e-6)" "unprognostic (3.35e-3)" "unprognostic (1.96e-1)" "unprognostic (1.42e-3)" "unprognostic (1.52e-1)" 12.9 29.8 14.7 13.2 21.0 16.0 16.2 9.2 27.6 12.7 26.9 17.2 28.9 20.0 11.5 47.5 25.6 18.5 18.3 14.6 15.0 15.9 30.5 30.9 12.1 11.7 15.1 15.1 11.6 10.3 17.5 15.6 27.2 15.3 18.6 27.6 15.4 19.1 19.4 10.7 19.1 21.4 12.9 13.3 13.3 15.7 16.8 9.2 17.0 18.0 12.0 21.0 14.4 13.9 7.3 24.3 7.9 21.3 15.2 18.3 14.9 18.0 21.9 10.8 15.1 12.6 13.1 15.4 15.4 14.3 24.3 20.2 40.3 22.1 12.8 20.6 15.8 17.2 15.7 39.3 20.6 5.9 8.9 50.4 14.0 40.0 17.7 12.7 17.8 13.7 42.1 22.9 38.7 17.2 24.4 10.5 29.5 19.9 20.2 18.0 6.4 28.4 18.6 21.7 30.4 34.8 18.5 21.2 12.4 27.2 25.5 20.3 31.3 11.6 13.5 28.0 15.9 18.4 13.3 10.7 9.9 14.1 23.8 14.0 16.6 7.9 20.3 4.6 18.0 21.3 16.1 7.3 14.5 18.3 24.3 5.2 16.9 14.3 5.3 15.2 19.0 13.5 17.5 14.9 14.7 21.0 9.2 27.6 15.0 15.9 15.1 15.1 15.3 9.2 GSTA1 ENSG00000243955 "Glutathione S-transferase alpha 1" P08263 6 52791664-52803910 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adrenal gland: 119.4;intestine: 202.4;kidney: 79.7;liver: 214.4;testis: 78.2" "Cell line enriched" "Detected in some" 13 "Hep G2: 87.7" "Group enriched" "Detected in many" 6 "liver cancer: 555.4;renal cancer: 135.0" "Region enriched" "Detected in single" 6 "basal ganglia: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol Cytosol "HPA004342: AB_1078987, HPA048934: , HPA053817: " "unprognostic (4.84e-3)" "unprognostic (2.40e-2)" "unprognostic (3.40e-1)" "unprognostic (4.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-1)" "unprognostic (1.00e-2)" "prognostic favourable (8.66e-4)" "unprognostic (5.75e-2)" "unprognostic (6.90e-3)" "unprognostic (3.00e-1)" "unprognostic (8.27e-2)" "prognostic unfavourable (3.71e-4)" "unprognostic (1.21e-1)" "unprognostic (4.26e-3)" "unprognostic (1.02e-1)" "unprognostic (2.16e-2)" 0.6 119.4 0.6 0.7 4.2 0.0 0.6 0.6 0.7 0.8 64.3 4.3 0.6 59.9 0.6 1.2 0.7 6.9 16.4 0.6 0.6 0.0 79.7 214.4 7.1 0.6 0.6 0.6 8.5 16.9 0.0 0.7 0.9 0.7 1.8 0.2 1.0 2.6 0.8 0.6 0.1 202.4 0.6 0.6 0.6 10.7 78.2 0.6 0.7 0.6 2.1 4.4 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 87.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 4.2 0.6 0.7 0.6 0.0 0.6 0.6 0.7 0.6 GSTA2 GST2 ENSG00000244067 "Glutathione S-transferase alpha 2" P09210 6 52750089-52763569 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 63.4;liver: 192.2;pancreas: 54.1" "Group enriched" "Detected in some" 20 "CACO-2: 20.3;Hep G2: 15.5" "Group enriched" "Detected in many" 16 "liver cancer: 124.6;renal cancer: 48.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol Cytosol "HPA004342: AB_1078987, HPA048934: , HPA053817: " "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (6.43e-3)" "unprognostic (2.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "prognostic unfavourable (1.17e-4)" "unprognostic (4.34e-2)" "unprognostic (1.91e-1)" "unprognostic (6.54e-2)" 0.2 1.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 6.4 0.2 0.2 13.4 0.2 0.3 0.2 0.0 9.9 0.2 0.2 0.0 63.4 192.2 5.3 0.2 0.2 0.2 0.3 54.1 0.0 0.2 0.3 0.2 0.7 0.0 0.2 0.3 0.2 0.2 0.0 27.6 0.2 0.2 0.2 1.5 14.1 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 20.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 15.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.4 0.3 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 GSTA3 ENSG00000174156 "Glutathione S-transferase alpha 3" Q16772 6 52896639-52909685 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 36.5;fallopian tube: 32.4;placenta: 51.9" "Cell line enhanced" "Detected in some" "BEWO: 2.5;BJ hTERT+: 1.1;CACO-2: 1.5;HAP1: 2.8;HEK 293: 1.5;SK-BR-3: 2.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "pons and medulla: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004342, HPA048934, HPA053817" Approved Supported Cytosol Cytosol "HPA004342: AB_1078987, HPA048934: , HPA053817: " "unprognostic (7.51e-2)" "unprognostic (7.06e-3)" "unprognostic (3.10e-1)" "unprognostic (5.53e-2)" "unprognostic (4.38e-3)" "unprognostic (2.86e-3)" "unprognostic (1.81e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (9.35e-2)" 0.2 36.5 0.2 0.2 0.6 0.0 0.7 0.3 0.2 0.9 0.2 1.0 0.2 0.0 0.3 6.6 0.2 32.4 0.2 0.2 0.2 0.2 0.2 0.2 1.3 0.2 0.2 0.2 3.8 0.2 1.1 0.2 51.9 2.1 0.2 0.0 0.5 0.6 0.2 0.2 12.5 0.2 0.2 0.2 0.2 1.0 6.4 0.3 0.2 0.2 0.9 0.2 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.2 0.2 0.2 0.2 0.2 2.1 0.3 GSTA4 ENSG00000170899 "Glutathione S-transferase alpha 4" O15217 6 52977948-52995378 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 105.4" "Cell line enhanced" "Detected in many" "AF22: 32.2;ASC TERT1: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "non-classical monocyte: 17.4" "Lineage enriched" "Detected in many" 6 "monocytes: 17.4" "Low region specificity" "Detected in all" HPA048934 Approved "HPA048934: " "unprognostic (5.13e-3)" "unprognostic (2.75e-1)" "unprognostic (5.04e-2)" "unprognostic (1.38e-1)" "unprognostic (5.24e-2)" "unprognostic (3.63e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-2)" "unprognostic (5.05e-3)" "unprognostic (9.26e-2)" "unprognostic (3.31e-3)" "unprognostic (2.29e-2)" "unprognostic (1.34e-2)" "unprognostic (2.21e-1)" "unprognostic (4.07e-3)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" 6.3 105.4 15.0 3.4 27.0 0.8 12.2 23.8 29.6 11.2 6.7 13.2 4.3 7.2 12.2 21.0 18.6 8.8 7.8 6.7 16.7 17.8 10.7 11.3 15.1 2.8 11.7 19.2 18.4 10.2 29.1 27.3 16.2 21.6 14.0 8.5 15.5 13.9 10.1 10.6 45.2 6.6 8.9 11.3 5.1 12.1 12.7 6.8 0.9 8.5 18.4 9.4 5.9 13.6 2.8 1.9 0.0 17.4 3.1 3.1 0.9 0.4 3.4 32.2 26.3 18.5 31.9 2.9 4.8 11.1 3.1 5.2 4.9 0.1 0.3 3.2 8.6 1.4 22.7 4.4 3.9 0.8 10.3 1.1 2.8 17.2 13.6 0.0 0.7 27.1 6.6 4.1 3.3 18.9 4.0 5.1 10.3 0.0 0.4 0.1 12.1 5.9 0.8 13.5 5.7 11.0 0.5 14.3 20.8 0.1 3.3 8.2 0.8 1.0 9.9 3.4 7.9 3.3 3.6 7.0 0.8 0.1 5.1 0.6 3.6 0.0 0.0 0.0 3.1 1.0 2.0 0.9 0.8 1.5 0.8 2.8 0.6 0.9 0.0 3.1 17.4 1.9 0.9 0.9 15.0 27.0 23.8 29.6 16.7 17.8 11.7 19.2 21.6 6.8 GSTA5 ENSG00000182793 "Glutathione S-transferase alpha 5" Q7RTV2 6 52831655-52846095 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004342, HPA048934, HPA053817" Uncertain Approved Cytosol Cytosol "HPA004342: AB_1078987, HPA048934: , HPA053817: " "unprognostic (1.97e-2)" "unprognostic (2.83e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSTK1 GST13 ENSG00000197448 "Glutathione S-transferase kappa 1" Q9Y2Q3 7 143244093-143270854 "Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006311, HPA022904" Supported Supported Peroxisomes 1300000 Peroxisomes "HPA006311: AB_1849786, HPA022904: AB_1849787" "prognostic favourable (4.41e-6)" "unprognostic (2.40e-1)" "unprognostic (6.53e-2)" "unprognostic (4.49e-3)" "unprognostic (2.92e-2)" "unprognostic (1.15e-2)" "unprognostic (1.37e-1)" "unprognostic (2.99e-1)" "unprognostic (1.43e-1)" "unprognostic (3.76e-3)" "unprognostic (1.99e-2)" "unprognostic (7.27e-2)" "prognostic favourable (2.10e-6)" "unprognostic (2.66e-2)" "unprognostic (2.94e-1)" "unprognostic (9.13e-2)" "unprognostic (2.15e-2)" 38.0 45.3 14.0 45.3 19.9 29.0 43.0 5.6 19.6 30.4 69.0 19.9 35.7 58.0 24.8 39.8 37.8 27.4 55.2 56.4 15.0 13.1 67.6 97.1 35.4 52.2 24.3 16.3 22.7 39.9 46.2 20.7 41.5 23.9 28.0 43.5 34.4 72.9 35.8 38.9 30.0 91.0 22.2 17.5 58.5 34.8 18.9 20.8 27.1 48.0 56.6 50.3 29.4 26.6 32.8 57.1 35.7 75.4 22.3 99.0 95.2 27.1 19.6 2.7 24.4 43.3 62.2 13.0 16.1 27.6 14.4 28.8 11.8 69.8 15.5 23.0 23.2 41.2 10.7 25.2 12.6 29.8 11.6 12.6 14.7 18.5 29.8 15.2 20.6 56.1 31.0 16.6 11.8 38.2 17.6 18.9 38.5 20.9 15.5 27.6 6.5 29.7 13.4 0.4 30.6 49.9 15.0 11.3 15.4 29.5 48.1 24.4 23.1 21.3 22.5 7.8 7.3 20.5 13.6 32.4 15.2 3.5 28.3 61.3 16.1 35.7 67.9 25.8 41.1 74.8 39.6 32.8 76.4 52.4 57.1 21.9 39.5 38.1 21.2 22.3 75.4 23.9 99.0 95.2 14.0 19.9 5.6 19.6 15.0 13.1 24.3 16.3 23.9 20.8 GSTM1 "GST1, H-B, MU" ENSG00000134184 "Glutathione S-transferase mu 1" P09488 1 109687814-109709039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 163.2;seminal vesicle: 101.4" "Cell line enhanced" "Detected in some" "HEL: 26.6;HeLa: 31.8;HHSteC: 25.4;hTEC/SVTERT24-B: 23.0;HUVEC TERT2: 19.5;MOLT-4: 34.3" "Cancer enhanced" "Detected in all" "urothelial cancer: 63.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB022669, CAB047357, HPA048652, HPA055972, HPA055973" Approved Approved Cytosol Cytosol "CAB022669: , CAB047357: , HPA048652: , HPA055972: , HPA055973: " "unprognostic (2.22e-2)" "unprognostic (5.35e-2)" "unprognostic (3.87e-3)" "unprognostic (3.20e-1)" "unprognostic (4.95e-2)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (1.81e-1)" "unprognostic (2.41e-1)" "unprognostic (6.55e-2)" "unprognostic (2.34e-1)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (2.12e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-1)" "unprognostic (4.72e-3)" 14.5 25.4 15.2 6.9 15.6 2.9 8.2 5.6 19.2 22.0 7.8 16.9 0.0 7.7 9.8 20.2 22.5 13.8 8.2 6.4 14.4 6.8 14.1 163.2 7.7 1.0 7.8 32.1 29.0 18.2 41.4 5.3 2.9 8.2 38.1 6.6 25.7 11.8 101.4 25.1 18.8 17.7 18.2 6.8 21.7 7.5 15.1 11.2 10.9 7.6 1.6 14.5 30.8 19.5 14.6 34.9 14.1 18.9 13.3 17.3 10.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 2.2 8.2 0.0 12.7 0.4 0.0 0.1 0.2 0.0 0.1 26.6 31.8 0.5 25.4 0.0 0.2 0.0 0.0 23.0 0.1 19.5 0.0 17.8 0.7 0.0 34.3 0.2 17.1 0.0 0.1 0.1 3.3 2.8 0.0 1.6 0.2 0.0 0.1 0.1 0.3 14.0 0.0 11.4 0.6 0.2 0.0 14.3 18.8 1.1 9.8 0.3 0.6 0.7 12.2 14.1 14.8 18.9 15.7 14.6 15.8 13.7 34.9 14.6 16.5 15.6 1.0 13.3 7.4 19.2 17.3 10.0 15.2 15.6 5.6 19.2 14.4 6.8 7.8 32.1 8.2 11.2 GSTM2 GST4 ENSG00000213366 "Glutathione S-transferase mu 2" P28161 1 109668022-109709551 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 41.0;HSkMC: 40.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB040547, HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" 930000 Cytosol "Cytokinetic bridge" "CAB040547: , HPA055972: , HPA055973: " "unprognostic (2.51e-3)" "unprognostic (1.28e-1)" "unprognostic (2.04e-2)" "unprognostic (2.57e-2)" "unprognostic (2.20e-1)" "unprognostic (5.04e-2)" "unprognostic (7.31e-2)" "prognostic favourable (9.70e-5)" "unprognostic (1.51e-2)" "unprognostic (7.43e-2)" "unprognostic (1.80e-3)" "unprognostic (2.94e-1)" "unprognostic (1.48e-3)" "unprognostic (1.07e-2)" "unprognostic (1.87e-1)" "unprognostic (2.32e-1)" "unprognostic (2.14e-1)" 23.8 27.3 30.7 14.7 48.3 5.7 31.7 13.7 25.0 36.4 20.9 19.9 54.3 14.5 24.0 37.1 15.4 31.4 15.7 35.2 32.5 21.7 15.9 6.0 11.1 7.5 17.0 21.1 90.1 17.8 20.4 40.2 5.8 22.4 30.7 10.7 36.0 26.6 87.5 88.5 39.2 13.6 22.0 24.9 10.7 16.4 9.2 28.9 6.7 20.4 25.6 8.7 20.2 31.0 5.2 16.5 16.0 3.5 8.9 20.9 5.8 0.0 1.2 12.9 13.1 15.4 41.0 2.4 8.1 14.3 7.5 9.6 2.3 0.0 0.2 8.7 20.3 0.0 1.0 0.0 9.8 0.4 0.2 4.6 0.1 3.0 10.4 0.4 8.6 40.5 0.3 11.2 0.0 5.3 1.3 0.2 16.3 0.1 6.3 8.0 2.3 10.9 7.8 0.0 0.0 2.3 0.2 2.8 6.4 0.0 0.3 4.2 13.1 2.3 0.1 8.4 0.4 12.0 0.6 4.0 5.9 0.4 12.6 0.1 0.1 1.0 2.2 16.0 1.9 3.5 1.8 5.2 5.3 2.0 12.7 3.7 20.9 8.9 1.3 8.9 2.1 16.5 4.5 5.8 30.7 48.3 13.7 25.0 32.5 21.7 17.0 21.1 22.4 28.9 GSTM3 GST5 ENSG00000134202 "Glutathione S-transferase mu 3" P21266 1 109733932-109741038 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 115.3;testis: 96.0" "Cell line enhanced" "Detected in many" "SK-BR-3: 44.8;T-47d: 94.8;WM-115: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 11.1" "Group enriched" "Detected in many" 7 "granulocytes: 4.1;T-cells: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB017130, HPA035190, CAB040583, HPA055972" Enhanced Supported Cytosol 560000 Cytosol "CAB017130: , CAB040583: , HPA035190: AB_10795023, HPA055972: " "unprognostic (2.13e-2)" "unprognostic (2.76e-2)" "unprognostic (1.95e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.28e-3)" "unprognostic (1.98e-1)" "prognostic unfavourable (1.89e-4)" "unprognostic (3.45e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-1)" "unprognostic (6.16e-3)" "unprognostic (1.38e-2)" "unprognostic (1.21e-2)" "unprognostic (1.90e-2)" "unprognostic (3.48e-2)" 7.5 11.3 21.4 2.9 27.8 0.9 23.1 8.5 18.4 15.4 11.7 9.9 51.0 12.6 9.0 67.2 11.1 8.8 12.3 27.6 14.0 14.4 54.0 5.3 5.2 2.4 9.6 22.0 32.3 26.5 7.3 9.4 5.8 30.7 13.6 5.6 13.4 4.5 115.3 15.5 15.0 7.5 15.9 13.3 3.3 14.2 96.0 6.4 0.1 15.8 15.6 3.3 17.4 12.0 0.6 0.8 4.1 0.3 1.0 11.1 1.4 0.0 1.3 9.7 0.0 13.2 8.1 1.6 10.5 1.8 11.5 11.2 4.2 0.3 0.0 6.1 5.3 0.5 1.9 4.3 16.0 0.0 2.9 9.8 31.8 6.3 14.1 0.0 22.8 8.1 5.3 17.3 0.0 14.2 0.8 0.1 5.1 5.7 2.6 0.2 1.0 18.2 0.0 6.2 0.4 3.2 22.5 17.1 9.2 21.9 44.8 2.0 94.8 14.3 11.1 0.1 4.2 11.8 6.9 1.5 2.4 0.0 0.1 0.0 36.8 0.8 0.3 4.1 4.2 0.1 1.2 0.6 5.3 3.1 0.1 0.6 11.1 5.5 2.0 1.0 0.2 0.8 2.3 1.4 21.4 27.8 8.5 18.4 14.0 14.4 9.6 22.0 30.7 6.4 GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656081-109674836 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 85.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "eosinophil: 69.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 69.8" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" 660000 Cytosol "Cytokinetic bridge" "HPA048652: , HPA055972: , HPA055973: " "prognostic favourable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" 12.5 17.6 14.0 12.3 20.2 3.6 10.9 12.9 24.7 12.6 33.2 18.0 9.4 85.3 12.1 15.3 15.9 11.0 14.5 14.7 13.7 12.3 27.2 22.0 7.4 10.1 14.8 16.9 31.4 12.2 23.1 9.9 5.1 15.8 14.7 23.2 20.5 15.4 26.3 47.4 10.6 77.2 19.0 16.1 16.2 14.7 11.8 14.0 4.0 14.9 14.5 12.8 22.2 14.2 3.6 7.8 69.8 3.0 2.5 3.1 2.3 5.3 2.4 4.3 32.5 9.7 15.0 5.5 1.7 14.0 4.1 5.4 17.1 0.6 5.0 6.7 7.7 5.5 11.1 5.8 2.6 7.4 0.0 10.8 10.0 15.3 15.8 3.7 13.2 9.4 5.8 5.2 0.0 3.3 5.0 7.5 2.8 4.9 3.1 16.4 3.3 12.9 6.6 2.4 7.3 16.0 3.8 3.0 7.2 0.0 28.1 21.7 7.6 8.0 1.4 4.7 18.7 5.2 2.5 11.2 19.6 0.4 15.5 5.5 13.3 2.0 2.9 69.8 2.7 3.0 1.6 3.6 2.0 3.1 7.8 2.8 2.0 2.3 0.4 2.5 0.7 2.7 2.8 2.3 14.0 20.2 12.9 24.7 13.7 12.3 14.8 16.9 15.8 14.0 GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109712255-109775428 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "breast: 237.6;ovary: 66.1" "Group enriched" "Detected in some" 7 "fHDF/TERT166: 17.6;HHSteC: 7.6;HSkMC: 8.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 5.7" "Group enriched" "Detected in many" 5 "dendritic cells: 5.7;T-cells: 1.9" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Cytosol "Cytokinetic bridge" "HPA048652: , HPA055972: , HPA055973: " "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" 5.8 3.5 25.7 2.6 23.4 1.6 237.6 15.8 24.6 27.2 4.2 14.0 4.7 2.1 14.0 12.0 4.8 19.8 9.0 4.8 24.9 6.2 2.9 2.1 5.7 2.6 4.9 17.9 66.1 2.7 1.6 2.7 1.6 8.9 12.8 4.0 23.0 3.9 11.9 2.4 3.7 3.5 9.8 11.0 3.5 3.9 5.1 11.9 0.0 2.6 2.1 3.2 10.5 16.1 0.0 5.7 0.6 0.2 0.7 1.9 0.9 0.0 0.0 0.0 0.0 1.5 1.5 0.2 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.6 0.1 0.1 0.1 0.0 0.0 0.1 1.3 0.0 0.2 0.2 0.0 0.7 0.0 5.7 1.9 0.9 25.7 23.4 15.8 24.6 24.9 6.2 4.9 17.9 8.9 11.9 GSTO1 "GSTTLp28, P28" ENSG00000148834 "Glutathione S-transferase omega 1" P78417 10 104235356-104267459 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 137.3" "Cell line enhanced" "Detected in many" "SK-MEL-30: 121.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037603, HPA037604" Enhanced Approved Nucleoplasm,Cytosol 200000000 Cytosol Nucleoplasm "HPA037603: AB_2675574, HPA037604: AB_10672283" "prognostic favourable (6.95e-4)" "unprognostic (9.23e-2)" "unprognostic (1.43e-2)" "unprognostic (6.83e-2)" "unprognostic (7.16e-2)" "prognostic unfavourable (8.83e-4)" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (9.23e-3)" "unprognostic (4.57e-2)" "unprognostic (7.65e-2)" "unprognostic (2.13e-1)" "prognostic unfavourable (2.11e-4)" "unprognostic (1.86e-2)" "unprognostic (1.29e-1)" "unprognostic (5.51e-3)" "unprognostic (5.82e-2)" 29.6 31.9 19.9 21.8 24.4 35.8 20.0 15.0 24.3 17.8 29.7 16.8 17.8 36.3 16.5 21.4 22.6 15.2 24.7 67.9 19.7 21.5 32.7 137.3 32.0 35.7 23.2 23.1 19.7 21.2 18.6 23.2 26.3 17.0 18.2 20.8 18.0 25.3 21.2 42.7 13.3 41.0 21.4 18.9 26.8 19.8 7.0 14.2 30.8 32.9 24.0 16.8 28.0 18.8 18.7 55.4 85.5 68.3 21.8 25.5 68.0 31.0 21.3 16.5 28.2 23.2 44.3 7.2 40.6 72.1 26.9 29.4 26.7 33.2 27.7 17.6 26.9 17.9 10.8 36.0 28.4 13.8 25.9 20.4 15.2 58.3 41.5 26.1 34.3 33.6 15.4 39.1 47.3 51.5 41.9 17.3 56.4 16.9 20.3 36.8 15.2 14.9 14.9 10.8 11.7 40.0 20.0 8.2 10.3 13.1 9.4 121.1 10.3 21.1 47.5 32.0 16.8 49.7 36.1 0.3 0.4 0.2 59.9 45.5 12.6 85.5 68.3 19.2 18.3 57.2 22.0 18.7 22.6 23.4 55.4 15.0 19.7 19.8 19.5 21.8 43.9 25.7 25.5 68.0 19.9 24.4 15.0 24.3 19.7 21.5 23.2 23.1 17.0 14.2 GSTO2 ENSG00000065621 "Glutathione S-transferase omega 2" Q9H4Y5 10 104268873-104304945 "Enzymes, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 24.8;hTCEpi: 21.6;hTERT-HME1: 23.4;MCF7: 14.1;T-47d: 18.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048141 Approved "HPA048141: " "unprognostic (5.77e-2)" "unprognostic (6.69e-2)" "unprognostic (7.15e-2)" "unprognostic (1.80e-1)" "unprognostic (2.48e-1)" "unprognostic (3.11e-2)" "unprognostic (3.12e-1)" "unprognostic (2.15e-1)" "unprognostic (7.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "prognostic favourable (7.10e-7)" "unprognostic (4.56e-2)" "unprognostic (3.92e-2)" "unprognostic (1.75e-2)" "unprognostic (3.47e-1)" 0.9 3.8 7.5 2.2 15.7 2.1 13.1 2.1 9.8 6.7 6.8 6.9 15.5 6.2 4.3 16.7 11.0 10.6 6.7 1.0 4.6 4.8 10.6 3.3 3.7 0.6 3.5 7.6 7.1 37.3 18.1 24.0 1.3 3.2 10.6 8.8 9.4 13.2 18.0 1.8 12.3 6.0 2.8 3.2 1.0 9.8 30.3 5.4 1.7 10.7 9.6 4.5 5.9 6.7 1.3 1.0 5.1 0.7 2.9 3.7 0.8 9.5 0.8 0.2 0.4 0.3 0.9 1.1 4.5 8.3 2.3 2.4 0.2 24.8 1.3 4.3 0.5 13.1 0.3 5.6 0.7 0.5 1.7 0.2 2.1 1.4 2.2 0.3 0.3 1.8 21.6 0.1 23.4 0.4 0.7 2.0 0.6 14.1 0.1 0.2 0.9 0.8 0.3 0.3 0.3 6.0 7.1 0.4 0.5 3.2 2.4 1.3 18.4 0.1 1.2 0.7 3.8 0.4 0.2 1.7 3.4 0.2 0.7 0.4 0.2 0.5 0.5 2.4 1.3 0.7 1.3 1.0 1.9 0.8 0.2 1.3 2.1 1.3 5.1 2.9 0.3 1.0 3.7 0.8 7.5 15.7 2.1 9.8 4.6 4.8 3.5 7.6 3.2 5.4 GSTP1 "FAEES3, GST3, GSTP" ENSG00000084207 "Glutathione S-transferase pi 1" P09211 11 67583595-67586656 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 298.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019779, HPA019869" Enhanced Supported Mitochondria,Cytosol 120000000 "Mitochondria, Cytosol" "HPA019779: AB_1849799, HPA019869: AB_1849801" "unprognostic (9.81e-2)" "unprognostic (6.52e-2)" "unprognostic (7.24e-2)" "unprognostic (2.72e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-3)" "unprognostic (3.27e-1)" "unprognostic (4.98e-2)" "unprognostic (1.28e-1)" "unprognostic (5.16e-3)" "unprognostic (2.14e-3)" "unprognostic (9.37e-2)" "unprognostic (5.72e-2)" "unprognostic (7.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.72e-3)" "unprognostic (1.48e-1)" 24.2 25.3 20.2 23.8 21.7 46.2 39.5 15.5 19.8 51.8 51.9 23.5 125.4 35.2 43.5 41.9 181.6 60.8 51.1 45.3 18.3 23.5 44.2 5.9 61.0 39.4 25.5 19.9 33.4 60.7 44.1 33.8 57.9 46.0 37.0 17.9 59.9 50.2 110.8 33.7 58.5 34.0 30.1 22.8 25.1 48.5 15.4 15.4 29.8 91.6 131.5 75.6 40.8 79.5 25.3 191.4 12.4 168.2 70.1 40.7 167.2 68.1 93.0 45.3 70.5 35.1 39.6 41.9 29.8 40.0 45.6 35.5 170.8 71.7 0.1 68.4 47.1 99.7 122.4 131.2 12.9 47.5 44.5 3.3 67.7 0.0 52.1 22.4 39.9 49.1 298.4 36.3 35.1 68.3 73.9 19.0 35.6 0.2 51.3 62.5 86.7 39.9 47.9 7.6 0.2 72.5 0.2 15.4 44.0 41.8 13.6 135.0 0.2 37.7 36.8 21.0 53.4 44.0 21.6 11.8 73.8 25.0 23.9 37.1 43.6 2.3 168.2 12.4 40.7 125.7 15.0 25.3 18.4 33.3 191.4 24.3 15.3 27.3 7.0 70.1 79.4 76.2 18.3 167.2 20.2 21.7 15.5 19.8 18.3 23.5 25.5 19.9 46.0 15.4 GSTT2B GSTT2P ENSG00000133433 "Glutathione S-transferase theta 2B (gene/pseudogene)" P0CG30 22 23957414-23961186 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "breast: 83.4" "Cell line enhanced" "Detected in many" "AN3-CA: 22.4;HHSteC: 33.0;SK-MEL-30: 22.8;T-47d: 25.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA000750 Uncertain Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA000750: AB_1849804" "prognostic favourable (5.06e-4)" "unprognostic (5.14e-2)" "unprognostic (1.90e-1)" "unprognostic (4.51e-2)" "unprognostic (7.13e-2)" "unprognostic (8.41e-3)" "unprognostic (2.58e-1)" "unprognostic (7.99e-2)" "unprognostic (1.15e-1)" "unprognostic (1.92e-1)" "unprognostic (1.76e-2)" "unprognostic (4.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.48e-2)" "unprognostic (2.19e-3)" 1.6 11.7 2.7 0.7 1.9 0.0 83.4 0.0 4.2 2.6 1.5 0.1 1.7 2.9 2.6 1.4 1.1 2.4 1.7 2.9 1.3 6.1 2.0 0.1 2.5 3.1 3.2 0.9 3.6 0.8 6.1 0.2 1.2 2.5 1.3 11.4 0.7 2.7 1.4 0.9 2.6 0.5 2.5 0.1 0.7 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 6.4 0.3 0.0 22.4 0.4 0.5 0.9 3.1 1.8 4.6 4.8 9.6 0.0 0.0 5.1 7.8 9.4 0.0 9.9 2.1 0.0 0.8 0.3 12.6 1.5 33.0 0.0 3.6 13.6 1.6 13.1 2.7 3.6 0.0 0.0 2.7 0.1 0.0 0.0 0.1 4.7 0.0 16.7 0.0 10.1 0.0 0.4 9.4 3.1 0.0 22.8 25.2 0.3 12.2 3.8 2.5 0.5 2.4 0.0 0.0 0.0 2.4 0.0 9.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 GSTZ1 "GSTZ1-1, MAAI, MAI" ENSG00000100577 "Glutathione S-transferase zeta 1" O43708 14 77320884-77331597 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Isomerase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 90.4" "Cell line enhanced" "Detected in all" "MCF7: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004701 Approved Approved Nucleoplasm,Cytosol 62000 Cytosol Nucleoplasm "HPA004701: AB_1078990" "prognostic favourable (4.93e-4)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (2.16e-3)" "unprognostic (4.55e-1)" "unprognostic (3.03e-2)" "unprognostic (8.03e-3)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "prognostic favourable (3.73e-4)" "unprognostic (7.90e-2)" "unprognostic (1.73e-1)" "prognostic favourable (1.12e-7)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (4.12e-1)" "unprognostic (4.92e-2)" 4.6 12.9 5.6 5.9 6.8 2.8 8.5 2.1 9.0 5.0 8.1 10.8 7.5 8.1 4.1 9.5 9.0 5.5 8.0 5.5 5.4 5.0 8.9 90.4 4.4 10.7 6.9 6.9 2.8 7.1 9.3 5.1 11.0 5.8 8.0 8.0 9.5 22.5 4.7 14.8 7.4 7.2 3.8 7.9 5.0 5.9 18.2 5.2 8.6 8.3 14.3 8.9 4.9 4.5 8.2 15.3 7.2 16.0 3.4 5.6 5.0 6.4 12.4 9.8 6.9 6.2 8.6 16.6 4.1 4.1 7.6 10.8 4.2 16.4 14.4 5.8 4.8 8.3 6.7 7.8 7.3 7.6 6.6 7.0 4.7 8.8 9.8 2.6 5.8 8.1 8.5 4.4 7.5 6.5 5.8 13.3 5.1 60.2 4.0 5.5 2.9 9.9 6.9 10.3 11.2 11.6 8.0 10.8 9.8 9.0 18.0 12.7 29.4 3.8 4.4 5.9 20.2 6.7 3.0 10.0 10.7 12.7 15.5 3.9 7.5 6.6 11.1 7.2 1.9 16.0 1.9 6.4 3.4 2.8 15.3 8.2 2.9 2.4 1.1 3.4 13.5 10.4 5.6 5.0 5.6 6.8 2.1 9.0 5.4 5.0 6.9 6.9 5.8 5.2 GTF2F2 "BTF4, RAP30, TFIIF" ENSG00000188342 "General transcription factor IIF subunit 2" P13984 13 45120515-45284909 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006912 Supported Supported Nucleoplasm,Microtubules Nucleoplasm Microtubules "HPA006912: AB_1080256" "unprognostic (3.39e-1)" "unprognostic (2.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.29e-1)" "unprognostic (4.51e-2)" "prognostic unfavourable (1.65e-5)" "unprognostic (3.67e-2)" "unprognostic (3.17e-1)" "unprognostic (3.36e-2)" "unprognostic (2.53e-3)" "unprognostic (2.31e-2)" "unprognostic (4.76e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.53e-3)" "unprognostic (3.94e-2)" "unprognostic (6.44e-3)" 15.1 24.7 23.5 21.1 23.6 22.5 20.9 12.0 21.0 16.3 21.8 14.8 18.5 14.9 16.8 23.4 21.8 12.0 15.9 27.5 21.4 21.1 18.3 16.0 15.1 17.5 22.9 19.0 17.3 14.6 16.5 27.5 23.9 18.2 16.7 21.2 18.2 20.8 20.2 32.0 31.5 12.9 28.2 19.5 17.8 15.2 22.2 24.2 22.6 19.2 27.7 19.9 20.5 19.0 15.4 16.3 24.9 15.3 16.1 12.9 8.5 15.4 5.8 11.0 8.1 6.7 9.9 9.1 17.0 11.2 17.3 17.0 9.7 24.2 15.5 9.6 12.4 17.2 16.4 13.6 25.4 11.7 14.2 18.3 7.8 12.6 10.8 20.2 10.5 8.3 21.0 12.9 21.9 11.0 12.9 5.9 46.6 8.6 14.8 23.4 13.0 14.2 14.0 8.3 8.9 37.7 5.4 5.9 9.8 8.6 8.5 14.1 6.9 16.6 8.7 14.6 12.4 11.5 28.9 3.8 5.1 15.5 17.0 13.1 15.2 12.0 14.2 24.9 9.7 14.1 11.5 15.3 11.3 11.5 16.3 15.4 12.9 12.6 19.8 16.1 15.3 12.7 12.3 8.5 23.5 23.6 12.0 21.0 21.4 21.1 22.9 19.0 18.2 24.2 GTF3C4 "KAT12, TFIIIC90" ENSG00000125484 "General transcription factor IIIC subunit 4" Q9UKN8 9 132670035-132694955 "Enzymes, Predicted intracellular proteins" Transcription "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069369 Supported Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA069369: " "unprognostic (7.02e-2)" "unprognostic (9.01e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-2)" "unprognostic (1.58e-1)" "unprognostic (1.76e-1)" "unprognostic (4.77e-1)" "unprognostic (1.92e-2)" "prognostic favourable (2.99e-4)" "unprognostic (1.65e-1)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" 6.9 8.5 12.3 6.6 11.6 7.8 11.6 23.8 13.9 10.8 8.0 7.0 5.6 5.3 10.2 9.3 11.4 9.5 7.4 7.8 8.7 8.1 8.7 7.4 8.9 10.9 9.4 11.6 15.0 8.4 16.6 10.1 9.7 8.9 8.9 7.7 7.6 11.3 8.4 11.6 14.5 6.6 8.6 5.6 6.3 8.1 16.9 6.4 11.6 13.3 5.3 9.3 8.8 7.9 2.3 2.1 1.5 1.5 2.1 3.1 0.9 8.3 12.0 15.3 13.0 7.6 8.9 11.0 8.1 10.7 11.5 8.5 14.6 6.3 13.1 5.5 10.5 19.5 23.3 13.2 12.8 7.9 9.6 11.0 17.3 6.2 7.4 16.2 7.0 6.9 10.1 11.7 15.4 9.8 17.9 6.7 8.3 13.7 9.9 7.6 19.3 11.7 9.8 18.5 11.5 8.5 7.1 21.2 14.4 14.5 14.8 9.0 20.6 6.7 10.2 19.1 10.7 8.7 12.1 2.8 6.3 14.6 8.1 10.3 11.7 0.1 1.5 1.2 2.5 1.3 2.0 2.3 2.2 3.1 1.2 2.2 2.3 2.4 1.5 2.1 1.2 2.1 2.0 0.9 12.3 11.6 23.8 13.9 8.7 8.1 9.4 11.6 8.9 6.4 GUCY1A1 "GC-SA3, GUC1A3, GUCY1A3" ENSG00000164116 "Guanylate cyclase 1 soluble subunit alpha 1" Q02108 4 155666711-155732349 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 55.2" "Cell line enhanced" "Detected in some" "HAP1: 6.0;Karpas-707: 8.5;MOLT-4: 15.6;RPTEC TERT1: 10.7;RT4: 12.5;SH-SY5Y: 7.9" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 7.6;non-classical monocyte: 9.2;plasmacytoid DC: 11.6" "Group enriched" "Detected in many" 27 "dendritic cells: 11.6;monocytes: 9.2;NK-cells: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010887, HPA056004, HPA058617" Uncertain Supported Nucleoplasm 6100 Nucleoplasm "CAB010887: AB_259901, HPA056004: , HPA058617: " "unprognostic (4.81e-3)" "unprognostic (2.60e-1)" "unprognostic (3.03e-1)" "unprognostic (2.15e-1)" "unprognostic (1.99e-2)" "unprognostic (7.77e-3)" "unprognostic (1.07e-1)" "prognostic favourable (2.38e-4)" "unprognostic (1.85e-3)" "unprognostic (6.46e-2)" "unprognostic (3.42e-2)" "unprognostic (7.16e-2)" "prognostic unfavourable (7.59e-4)" "unprognostic (1.60e-2)" "prognostic unfavourable (3.59e-4)" "unprognostic (2.27e-1)" "unprognostic (6.55e-3)" 10.9 5.3 12.4 10.2 19.9 0.9 11.1 3.4 11.6 13.7 31.2 7.3 2.8 5.6 14.7 6.0 7.0 6.8 8.3 21.0 9.0 7.2 11.6 5.1 13.2 7.3 4.7 12.5 5.4 8.5 55.2 5.8 16.3 6.3 17.2 6.9 39.7 7.0 9.8 4.5 3.6 10.1 18.8 6.6 8.5 12.9 2.1 8.5 4.5 8.1 7.3 5.9 6.4 10.6 0.1 11.6 0.3 9.2 7.6 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 6.0 0.0 0.0 0.0 4.8 1.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 8.5 0.0 0.0 15.6 0.0 0.0 0.2 3.5 0.0 2.6 10.7 12.5 2.1 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.3 0.0 2.3 0.1 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 7.6 9.2 11.6 0.0 1.0 12.4 19.9 3.4 11.6 9.0 7.2 4.7 12.5 6.3 8.5 GUCY1A2 "GC-SA2, GUC1A2" ENSG00000152402 "Guanylate cyclase 1 soluble subunit alpha 2" P33402 11 106674012-107018524 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 23.0;placenta: 23.6" "Cell line enhanced" "Detected in some" "BJ hTERT+: 12.2;BJ hTERT+ SV40 Large T+ RasG12V: 14.3;HBF TERT88: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009534 Uncertain "CAB009534: AB_2279509" "unprognostic (7.53e-2)" "unprognostic (6.67e-2)" "unprognostic (7.99e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-2)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (6.53e-3)" "unprognostic (9.70e-3)" "unprognostic (8.00e-2)" "unprognostic (2.03e-1)" "prognostic unfavourable (3.02e-5)" "unprognostic (2.48e-4)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (1.09e-2)" 5.5 3.3 4.6 1.3 10.9 0.6 3.9 4.3 10.7 19.2 1.5 1.2 1.1 0.9 23.0 5.0 1.3 8.4 2.6 3.8 4.6 4.0 3.2 2.8 11.8 1.6 3.7 5.3 3.9 6.2 1.8 1.5 23.6 5.5 3.2 1.3 1.4 1.4 10.1 4.1 1.4 1.2 18.0 2.4 7.9 1.0 2.8 5.4 0.0 2.4 3.0 1.0 2.2 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 4.3 0.0 0.2 2.6 2.3 0.3 12.2 1.6 14.3 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 7.6 0.0 1.2 0.0 0.1 0.0 0.2 0.0 1.7 0.7 0.0 1.9 0.2 0.9 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.5 3.7 0.0 0.8 0.8 0.2 4.7 3.9 3.2 0.8 1.3 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 10.9 4.3 9.9 4.6 4.0 3.7 5.3 5.5 5.4 GUCY1B1 "GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3" ENSG00000061918 "Guanylate cyclase 1 soluble subunit beta 1" Q02153 4 155758992-155807591 "Enzymes, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 71.6" "Cell line enhanced" "Detected in many" "HEL: 24.8;Karpas-707: 13.1;MOLT-4: 15.6;RPTEC TERT1: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "intermediate monocyte: 5.6;non-classical monocyte: 17.8" "Lineage enriched" "Detected in many" 12 "monocytes: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010890, HPA020870" Approved Approved Cytosol 5200 Cytosol "CAB010890: AB_259911, HPA020870: AB_1850444" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (9.10e-3)" "unprognostic (4.69e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (6.69e-3)" "unprognostic (3.03e-3)" "unprognostic (1.47e-1)" "unprognostic (8.37e-2)" "unprognostic (2.84e-1)" "prognostic unfavourable (2.42e-4)" "unprognostic (7.35e-3)" "prognostic unfavourable (3.23e-4)" "unprognostic (2.14e-1)" "unprognostic (6.36e-3)" 8.8 5.4 18.7 9.8 42.0 1.8 5.5 12.2 36.8 8.1 14.9 5.7 0.4 4.2 11.3 4.7 5.9 9.5 9.2 12.2 16.1 25.0 9.2 5.4 9.4 6.6 14.5 23.2 3.7 7.4 71.6 3.8 28.0 20.6 9.8 6.2 5.8 3.2 8.7 3.8 2.2 5.9 16.3 6.7 7.2 8.9 2.1 5.5 2.6 4.6 2.4 5.1 8.0 6.8 0.2 1.4 1.1 17.8 0.9 0.0 4.8 0.0 0.2 3.5 0.0 1.2 6.6 0.0 1.1 1.9 0.1 0.0 0.0 0.0 0.0 1.7 0.6 0.0 7.3 0.1 0.4 0.0 2.6 24.8 0.0 0.0 0.7 0.0 0.0 2.9 0.2 0.0 0.1 0.0 0.0 13.1 1.7 1.1 15.6 0.0 0.2 1.8 1.8 0.5 0.4 25.2 2.3 0.4 4.4 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.9 7.1 5.2 0.1 0.0 0.0 9.0 0.0 0.0 1.1 0.4 0.3 0.0 5.6 0.0 0.1 0.0 0.0 1.4 0.2 0.0 0.0 0.4 0.9 17.8 1.2 0.0 4.8 18.7 42.0 12.2 36.8 16.1 25.0 14.5 23.2 20.6 5.5 GUCY2C "GUC2C, STAR" ENSG00000070019 "Guanylate cyclase 2C" P25092 12 14612632-14696585 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 85.1" "Cell line enhanced" "Detected in some" "AN3-CA: 3.7;BEWO: 2.2;CACO-2: 3.1;CAPAN-2: 4.5;SiHa: 4.2" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.9;stomach cancer: 9.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "memory B-cell: 4.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037655, HPA073759" Uncertain Uncertain Vesicles Vesicles "HPA037655: AB_10672388, HPA073759: " "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" "unprognostic (3.58e-2)" "unprognostic (2.11e-2)" "unprognostic (1.60e-2)" "unprognostic (5.67e-3)" "prognostic unfavourable (1.37e-5)" "unprognostic (9.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (1.58e-1)" "unprognostic (5.40e-2)" "unprognostic (2.35e-4)" "unprognostic (8.02e-2)" "unprognostic (1.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.98e-1)" 0.2 0.1 0.2 3.4 0.2 0.0 0.2 0.2 0.2 0.2 38.8 0.2 0.2 28.0 0.3 0.2 0.4 0.2 0.3 0.4 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.5 0.0 0.2 0.2 0.2 0.2 17.5 0.2 0.5 0.2 0.2 1.0 85.1 0.3 0.2 0.2 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 4.3 0.7 2.7 1.7 0.0 0.0 0.6 1.1 0.1 0.0 3.7 0.0 0.0 2.2 0.1 0.0 0.0 0.0 3.1 4.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.4 0.4 0.0 0.0 0.0 0.5 0.1 0.6 0.0 0.5 4.2 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.9 0.1 1.3 0.8 1.3 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.5 0.0 4.3 0.0 0.0 0.7 2.3 0.0 0.0 2.7 0.0 0.0 0.7 0.0 0.6 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 GUK1 ENSG00000143774 "Guanylate kinase 1" Q16774 1 228139962-228148984 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028118, HPA048587" Approved Uncertain Nucleoplasm,Cytosol 240000 "Nucleoplasm, Cytosol" "HPA028118: AB_2756308, HPA048587: AB_2680453" "unprognostic (9.15e-2)" "unprognostic (2.63e-2)" "unprognostic (3.60e-3)" "unprognostic (7.91e-2)" "unprognostic (8.54e-3)" "unprognostic (1.24e-1)" "unprognostic (3.55e-3)" "unprognostic (2.05e-1)" "unprognostic (3.47e-1)" "unprognostic (7.32e-2)" "unprognostic (3.38e-2)" "unprognostic (5.28e-2)" "prognostic unfavourable (8.85e-5)" "unprognostic (2.91e-1)" "unprognostic (5.41e-1)" "unprognostic (2.39e-2)" "unprognostic (6.12e-2)" 44.6 38.2 106.4 32.5 76.0 76.7 43.0 25.2 74.4 31.5 33.3 30.1 27.3 41.5 26.3 34.1 77.0 28.0 42.5 61.6 93.1 43.9 31.9 43.5 34.6 39.0 60.0 52.9 24.7 62.2 12.8 26.0 29.2 40.1 25.5 12.1 37.4 66.5 29.4 35.8 59.6 42.1 34.8 49.6 36.1 44.3 22.2 34.9 27.5 31.6 29.3 24.1 45.9 44.5 43.9 97.7 110.1 62.9 55.8 83.7 84.5 57.4 20.3 8.9 27.7 27.0 32.6 45.0 38.3 19.7 22.4 17.6 11.6 40.0 21.7 45.5 25.0 38.2 7.7 42.1 2.4 33.0 59.7 12.9 50.1 25.2 49.2 14.5 22.7 45.2 25.6 15.6 12.6 30.2 34.7 34.6 18.3 48.0 65.7 31.5 28.1 88.0 25.2 16.9 57.5 21.0 27.1 29.6 53.1 24.7 42.3 49.6 31.2 31.5 52.6 40.9 27.0 59.8 63.0 32.0 34.6 23.9 51.5 23.8 41.2 55.5 57.1 110.1 77.3 59.8 75.2 43.9 64.8 83.7 48.9 36.6 48.7 61.1 74.9 55.8 62.9 97.7 64.6 84.5 106.4 76.0 25.2 74.4 93.1 43.9 60.0 52.9 40.1 34.9 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982314 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" 48000 Vesicles "HPA036322: AB_10670796, HPA036323: " "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 23.5 12.0 3.7 7.9 5.5 20.7 25.4 5.7 4.4 10.4 14.6 7.7 22.0 10.0 10.4 12.2 9.3 7.6 11.1 8.0 3.7 2.9 11.8 50.4 15.3 12.3 6.3 3.1 8.6 17.1 9.0 7.3 30.0 4.5 12.1 11.4 9.9 17.2 11.8 5.9 10.0 16.1 8.3 3.9 17.5 11.0 7.9 5.8 14.7 17.7 5.9 13.0 9.2 7.4 9.7 27.7 22.1 36.0 15.2 11.5 15.8 16.8 6.5 6.4 14.3 21.9 13.1 9.3 5.3 14.9 11.8 10.9 9.3 17.4 7.7 8.4 6.8 6.9 4.1 6.4 7.0 7.2 8.4 10.5 9.8 6.4 10.7 22.4 17.5 9.0 6.9 6.8 8.9 10.2 15.9 55.9 7.6 12.2 8.2 24.1 4.3 5.5 8.5 14.8 43.7 7.4 10.2 9.4 8.3 14.3 33.6 18.7 18.7 22.4 7.2 14.4 13.1 5.4 13.3 31.8 38.1 13.0 10.8 29.9 17.5 7.4 28.1 22.1 11.5 36.0 10.3 9.7 9.0 10.2 27.7 7.8 6.2 7.3 4.5 15.2 30.0 11.3 11.3 15.8 3.7 5.5 5.7 4.4 3.7 2.9 6.3 3.1 4.5 5.8 GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888073-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 13.5;HSkMC: 12.9;MOLT-4: 23.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: " "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavourable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavourable (2.42e-5)" 8.7 7.2 3.1 6.2 4.0 2.1 5.2 1.1 4.0 10.2 4.5 8.1 3.4 0.9 8.4 9.3 4.2 6.7 12.4 20.6 3.4 2.4 2.2 1.0 5.2 2.4 5.6 4.7 24.8 11.9 2.8 3.8 4.9 4.2 11.3 2.7 10.7 8.0 5.2 2.2 2.6 2.5 12.0 5.4 1.0 2.6 8.4 4.7 14.9 12.1 3.7 2.3 12.2 6.9 0.4 3.0 1.7 0.1 0.8 1.4 0.1 0.1 1.2 0.0 7.5 6.9 13.5 1.1 1.2 2.8 2.7 6.6 0.3 0.8 0.0 2.1 3.2 0.1 0.7 1.5 2.6 0.0 0.9 0.0 5.0 7.9 8.7 3.1 0.0 12.9 0.7 6.5 1.0 0.0 3.7 0.1 1.6 1.7 23.1 0.1 4.4 1.5 0.1 6.4 0.0 0.8 1.1 0.7 3.4 6.4 0.3 0.8 2.5 1.0 0.0 2.9 9.3 9.0 4.2 0.7 0.1 0.1 7.6 1.5 5.1 0.4 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.4 0.2 0.2 1.7 0.8 0.1 3.0 1.4 0.1 3.1 4.0 1.1 4.0 3.4 2.4 5.6 4.7 4.2 4.7 GYG1 GYG ENSG00000163754 "Glycogenin 1" P46976 3 148991341-149027668 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 113.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030497 Approved Supported Vesicles Vesicles "HPA030497: AB_10602326" "unprognostic (2.68e-2)" "unprognostic (6.31e-3)" "unprognostic (3.21e-1)" "unprognostic (1.81e-1)" "unprognostic (6.19e-2)" "unprognostic (1.49e-2)" "prognostic unfavourable (6.15e-5)" "unprognostic (2.55e-2)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (7.75e-3)" "unprognostic (1.29e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" 10.8 7.9 7.0 8.5 8.5 55.7 10.0 9.2 7.5 10.6 31.0 6.0 11.9 4.8 15.6 15.4 18.1 11.1 12.0 32.0 8.0 9.0 8.5 6.3 9.1 14.7 11.6 7.1 13.3 14.3 6.5 7.8 6.5 10.0 16.3 7.6 7.7 11.3 19.4 113.0 4.7 8.4 32.5 8.1 13.6 12.8 47.3 7.4 4.2 9.4 39.6 8.5 28.7 14.6 7.0 26.7 16.8 26.7 17.7 32.5 17.5 18.5 12.0 9.0 10.0 24.9 26.1 12.2 27.4 22.8 40.0 37.4 15.7 19.0 0.0 13.6 31.7 5.7 23.5 12.1 40.4 6.2 10.1 14.2 5.7 17.8 22.5 14.4 21.4 14.3 19.8 13.2 16.7 22.9 8.7 33.8 22.9 32.6 2.8 11.5 10.7 9.8 7.9 13.6 26.6 11.0 17.4 7.4 3.5 14.4 19.9 15.5 19.8 15.4 19.0 20.5 6.1 14.6 20.0 30.7 17.1 13.2 17.3 22.2 6.6 7.2 23.4 16.8 17.4 24.5 32.5 7.0 11.6 18.1 26.7 5.1 6.3 10.7 11.6 17.7 26.7 10.7 15.9 17.5 7.0 8.5 9.2 7.5 8.0 9.0 11.6 7.1 10.0 7.4 GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828788-2882820 "Enzymes, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 76.7;brain: 21.2;breast: 30.4" "Cell line enhanced" "Detected in many" "AF22: 17.7;BEWO: 12.8;CACO-2: 13.1;Hep G2: 14.2;NTERA-2: 17.4;SK-MEL-30: 37.7" "Cancer enhanced" "Detected in all" "melanoma: 42.6" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol "Nucleoli, Cytosol" Nucleoplasm "HPA005495: AB_1079035, HPA064686: " "unprognostic (4.45e-2)" "unprognostic (4.21e-2)" "unprognostic (6.41e-3)" "unprognostic (8.50e-2)" "unprognostic (2.07e-3)" "unprognostic (5.16e-1)" "unprognostic (1.74e-2)" "unprognostic (1.18e-1)" "unprognostic (7.43e-3)" "unprognostic (6.74e-2)" "prognostic favourable (3.01e-5)" "unprognostic (9.76e-2)" "unprognostic (6.10e-5)" "unprognostic (1.78e-1)" "unprognostic (5.05e-3)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" 76.7 1.4 4.6 1.3 4.6 0.5 30.4 2.1 3.7 2.1 3.5 8.2 0.7 1.2 4.2 0.9 1.0 3.6 1.7 1.7 3.9 2.9 1.4 9.9 0.7 0.7 5.5 2.9 1.9 3.2 0.4 0.5 1.6 12.9 2.7 2.0 4.2 2.8 4.4 0.5 1.2 1.3 2.8 21.2 0.5 2.2 0.8 5.1 0.0 1.3 0.5 0.6 2.9 1.4 1.0 0.6 0.6 0.4 1.2 0.7 0.0 0.0 5.4 17.7 0.0 10.6 0.0 12.8 0.5 3.1 3.1 3.9 13.1 0.3 0.0 1.4 2.2 0.0 10.0 0.2 3.0 0.1 2.8 0.0 0.2 14.2 3.1 0.0 4.3 3.8 0.1 0.3 0.0 0.0 0.1 0.0 3.2 0.8 0.0 0.4 17.4 0.1 2.9 5.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 37.7 1.7 10.7 0.0 0.0 3.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.3 0.2 0.7 0.5 0.4 0.3 0.1 1.0 0.3 0.2 0.6 1.2 0.4 0.6 0.4 0.0 4.6 4.6 2.1 3.7 3.9 2.9 5.5 2.9 12.9 5.1 GYS1 "GSY, GYS" ENSG00000104812 "Glycogen synthase 1" P13807 19 48968125-48993310 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007793, HPA041598" Enhanced Approved Microtubules,Cytosol 10000 "Microtubules, Cytosol" "CAB007793: AB_562291, HPA041598: " "unprognostic (3.37e-1)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (6.83e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (3.30e-2)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" "prognostic unfavourable (3.46e-4)" "unprognostic (4.04e-2)" "unprognostic (6.76e-2)" "unprognostic (5.87e-3)" "unprognostic (3.81e-2)" 9.7 7.3 5.1 6.1 6.5 16.0 10.6 11.3 6.2 5.3 7.3 6.2 5.8 6.1 6.2 6.9 11.5 5.9 6.1 37.3 6.8 4.0 7.2 4.3 5.0 6.3 5.3 5.5 6.8 4.4 6.4 5.1 5.0 5.9 8.7 6.1 12.4 7.2 7.6 106.1 8.1 6.1 6.8 6.0 5.8 7.3 2.2 5.5 6.4 5.2 42.6 9.0 7.9 6.9 6.7 15.9 8.2 10.5 12.8 10.9 7.3 28.3 11.3 8.4 11.5 19.6 7.7 16.7 19.7 13.9 20.8 24.4 11.0 9.3 11.8 12.0 19.2 20.3 14.0 25.0 18.2 7.3 20.3 9.8 14.5 9.7 11.0 10.7 7.3 19.0 12.0 13.4 11.4 17.4 6.8 15.9 26.0 10.8 13.2 9.3 4.5 13.1 11.2 14.7 11.6 20.6 30.4 5.2 7.3 17.5 22.9 4.6 12.1 11.1 13.4 25.6 9.9 11.5 21.3 13.2 13.6 5.8 26.1 9.4 5.7 8.2 10.5 7.5 8.8 6.3 10.9 6.7 7.6 8.2 15.9 5.5 6.3 5.6 4.4 12.8 8.5 8.6 10.1 7.3 5.1 6.5 11.3 6.2 6.8 4.0 5.3 5.5 5.9 5.5 GYS2 ENSG00000111713 "Glycogen synthase 2" P54840 12 21536189-21604847 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 75.1" "Cell line enhanced" "Detected in some" "CACO-2: 5.1;HEL: 1.8" "Cancer enriched" "Detected in single" 29 "liver cancer: 12.6" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "naive CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 8 "T-cells: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039482 Approved "HPA039482: AB_10795107" "unprognostic (7.22e-3)" "unprognostic (2.85e-2)" "unprognostic (8.88e-2)" "unprognostic (1.78e-2)" "unprognostic (5.68e-2)" "unprognostic (3.16e-1)" "prognostic favourable (7.62e-5)" "unprognostic (1.06e-1)" "unprognostic (1.29e-1)" "unprognostic (1.68e-1)" "unprognostic (4.68e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-1)" "unprognostic (4.22e-2)" "unprognostic (6.53e-2)" "unprognostic (1.85e-1)" "unprognostic (2.66e-4)" 8.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.2 0.0 0.0 0.0 0.1 75.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 2.4 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 5.1 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.6 1.8 0.2 0.0 0.3 0.5 0.4 0.5 0.2 0.0 0.4 0.0 0.0 0.1 0.6 0.0 0.3 0.3 0.2 0.0 0.5 0.2 0.0 1.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.1 0.2 0.1 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102648-55110252 "Enzymes, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 92.3;intestine: 31.0;lymphoid tissue: 40.9" "Cell line enriched" "Detected in some" 4 "HL-60: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 13 "gdT-cell: 92.3;MAIT T-cell: 90.8;memory CD4 T-cell: 25.4;memory CD8 T-cell: 89.3;naive CD8 T-cell: 50.5;NK-cell: 61.9" "Group enriched" "Detected in many" 38 "NK-cells: 61.9;T-cells: 92.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054134 Approved "Secreted to blood" "HPA054134: " "prognostic favourable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favourable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavourable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" 4.3 1.8 1.1 16.3 1.2 10.0 2.5 0.7 0.8 3.9 12.5 0.9 1.3 10.3 5.2 2.9 2.9 2.9 9.6 4.5 1.1 1.1 4.6 5.2 11.8 20.3 1.7 0.9 3.0 5.8 0.0 1.9 5.8 1.5 3.4 6.3 4.5 5.1 1.3 2.6 1.2 31.0 2.5 2.6 40.9 3.9 1.1 0.6 1.9 3.1 4.2 11.1 6.6 2.9 0.2 0.2 2.0 0.3 61.9 92.3 52.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 92.3 0.2 90.8 0.2 25.4 89.3 0.2 0.1 5.2 50.5 2.0 61.9 0.3 0.2 2.9 52.0 1.1 1.2 0.7 0.8 1.1 1.1 1.7 0.9 1.5 0.6 GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "blood: 298.5" "Cell line enriched" "Detected in some" 5 "HMC-1: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in many" 5 "plasmacytoid DC: 298.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 298.5" "CAB000376, HPA003418" Enhanced "Secreted to blood" "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favourable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favourable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavourable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" 6.4 0.7 0.8 8.0 1.1 26.4 3.2 0.7 0.7 1.6 3.0 0.5 1.3 0.8 3.9 1.5 4.0 1.0 3.1 4.8 0.7 2.4 2.1 5.7 21.7 16.7 1.1 0.0 1.4 0.7 0.0 1.0 7.5 0.8 2.6 0.9 4.0 2.7 2.3 3.5 0.6 2.9 1.8 1.5 33.0 3.5 0.9 0.4 6.1 4.4 5.3 16.8 6.0 1.5 0.2 298.5 2.0 0.2 19.9 60.5 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 3.8 0.0 0.0 0.0 0.7 2.9 0.3 0.1 0.2 60.5 0.1 0.7 0.2 4.6 28.4 0.2 0.1 1.4 28.7 2.0 19.9 0.2 298.5 0.1 53.6 0.8 1.1 0.7 0.7 0.7 2.4 1.1 0.0 0.8 0.4 GZMH "CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2" ENSG00000100450 "Granzyme H" P20718 14 24606480-24609699 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "blood: 134.9" "Cell line enhanced" "Detected in some" "Hep G2: 1.5;RPMI-8226: 2.0;THP-1: 1.4;U-266/70: 4.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 134.9;memory CD4 T-cell: 41.8;memory CD8 T-cell: 109.7;naive CD8 T-cell: 102.7" "Lineage enriched" "Detected in many" 8 "T-cells: 134.9" "Low region specificity" "Detected in all" HPA029200 Enhanced "Secreted to blood" "HPA029200: AB_10602908" "unprognostic (3.72e-3)" "unprognostic (1.47e-3)" "unprognostic (5.35e-2)" "prognostic favourable (2.00e-6)" "unprognostic (8.80e-2)" "unprognostic (1.65e-3)" "unprognostic (2.08e-3)" "unprognostic (1.13e-1)" "unprognostic (1.62e-2)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "prognostic unfavourable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.80e-1)" "unprognostic (3.35e-2)" "unprognostic (2.77e-3)" 3.6 3.1 1.1 5.0 1.2 16.5 3.6 0.5 1.0 1.9 3.1 0.4 0.2 0.9 1.0 2.7 2.6 1.8 8.1 4.8 1.0 1.1 1.7 3.6 16.4 11.5 2.6 1.3 3.0 1.1 0.0 3.7 1.6 1.2 4.5 1.1 5.1 5.4 4.2 4.5 0.8 2.2 2.0 3.1 22.6 2.5 2.5 0.7 0.2 2.5 3.4 6.4 5.1 1.9 0.4 3.2 1.8 0.3 17.6 134.9 82.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.4 0.9 1.8 0.2 0.1 134.9 0.2 2.4 0.4 41.8 109.7 0.2 0.2 13.9 102.7 1.5 17.6 0.3 3.2 0.3 82.9 1.1 1.2 0.5 1.0 1.0 1.1 2.6 1.3 1.2 0.7 GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024253-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood: 95.8;lymphoid tissue: 37.3" "Cell line enhanced" "Detected in single" "U-2197: 1.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "MAIT T-cell: 95.8;memory CD8 T-cell: 59.0" "Group enriched" "Detected in many" 191 "NK-cells: 56.9;T-cells: 95.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA063181 Enhanced "Secreted to blood" "HPA063181: " "prognostic favourable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavourable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" 3.5 1.6 0.6 10.5 0.6 3.6 3.1 0.5 0.5 4.1 3.7 0.2 1.7 0.4 3.2 2.6 2.8 1.8 7.4 1.6 0.6 0.7 4.3 4.1 10.2 37.3 0.7 0.2 2.1 1.5 0.0 1.0 0.9 0.5 6.6 1.9 2.9 5.7 2.1 0.8 0.8 7.4 0.8 1.6 36.4 2.4 2.1 0.3 3.3 3.1 2.7 28.2 4.9 2.6 0.0 0.1 0.4 0.1 56.9 95.8 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.8 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.1 21.1 0.1 95.8 0.0 13.2 59.0 0.0 0.0 0.6 10.5 0.4 56.9 0.1 0.1 0.8 9.9 0.6 0.6 0.5 0.5 0.6 0.7 0.7 0.2 0.5 0.3 GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 79.2;lymphoid tissue: 28.6" "Cell line enhanced" "Detected in some" "EFO-21: 5.2;HDLM-2: 4.2;HMC-1: 5.3;MOLT-4: 3.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "gdT-cell: 79.2" "Group enriched" "Detected in many" 31 "NK-cells: 22.7;T-cells: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015624 Enhanced "Secreted to blood" "HPA015624: " "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favourable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favourable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavourable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" 1.8 1.0 0.7 13.6 0.9 15.6 1.0 4.3 1.4 1.0 3.5 0.2 0.1 1.8 1.0 2.9 2.0 1.1 4.7 1.6 0.7 0.6 1.1 2.6 4.8 15.1 0.7 0.4 0.8 0.4 0.0 0.9 1.6 0.5 1.7 0.1 1.5 12.0 0.3 0.8 0.7 5.1 0.5 1.1 21.1 3.0 1.5 0.4 28.6 1.4 1.1 10.9 1.1 1.2 0.4 0.4 1.6 0.2 22.7 79.2 27.0 0.1 0.7 0.1 0.3 0.2 0.0 0.7 0.0 0.1 0.1 0.0 0.6 0.2 0.1 5.2 0.0 0.1 0.0 0.0 0.0 4.2 0.4 0.0 0.6 0.2 0.6 0.4 5.3 0.2 0.0 0.1 0.0 0.1 1.6 0.3 0.0 1.2 3.4 1.4 0.9 0.8 0.3 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.8 0.9 0.0 1.1 0.4 1.1 0.3 0.8 0.3 0.8 0.1 0.1 79.2 0.2 49.8 0.1 26.4 63.6 0.1 0.4 25.8 53.1 1.6 22.7 0.2 0.4 12.2 27.0 0.7 0.9 4.3 1.4 0.7 0.6 0.7 0.4 0.5 0.4 H6PD GDH ENSG00000049239 "Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase" O95479 1 9234775-9271337 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 116.9" "Cell line enhanced" "Detected in many" "ASC diff: 28.6;ASC TERT1: 32.8;HSkMC: 32.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004824, HPA005440" Approved Uncertain Cytosol "Intracellular and membrane" 91000000 Cytosol "HPA004824: AB_1079037, HPA005440: AB_1079036" "unprognostic (4.83e-3)" "unprognostic (3.91e-2)" "unprognostic (1.18e-1)" "unprognostic (3.49e-1)" "unprognostic (5.53e-3)" "unprognostic (2.86e-2)" "unprognostic (8.35e-2)" "unprognostic (5.18e-2)" "unprognostic (9.73e-2)" "unprognostic (1.26e-3)" "unprognostic (2.16e-2)" "unprognostic (7.35e-3)" "unprognostic (8.20e-2)" "unprognostic (3.61e-1)" "unprognostic (1.30e-1)" "unprognostic (8.65e-2)" "unprognostic (1.95e-1)" 18.3 16.1 4.1 10.7 5.5 4.8 12.2 4.1 6.3 16.6 11.9 10.5 8.2 6.3 22.0 18.0 11.1 15.6 11.9 11.9 3.7 3.0 7.0 116.9 12.2 11.1 6.8 2.6 38.3 10.6 8.0 8.7 14.9 6.0 11.6 5.3 11.8 29.8 8.1 24.7 20.7 10.4 10.2 6.6 10.7 9.9 12.4 5.5 16.2 12.6 12.9 14.1 12.2 10.1 4.5 3.7 4.1 6.3 3.1 4.7 3.0 3.8 3.1 2.7 10.2 28.6 32.8 2.6 3.9 9.6 2.9 4.5 0.6 7.9 4.2 4.5 6.0 4.0 0.7 1.9 4.2 12.6 0.9 0.0 1.0 2.6 16.0 1.3 1.6 32.2 3.7 6.9 4.5 13.1 1.1 7.3 5.6 2.2 1.5 3.2 1.5 1.8 0.4 0.3 3.5 3.7 1.6 0.9 4.9 5.1 4.0 4.8 3.0 6.8 13.0 9.9 1.6 2.5 1.0 9.8 2.9 1.0 16.6 6.1 6.2 3.5 6.2 0.9 4.7 6.3 3.7 3.5 3.5 4.1 2.8 4.5 3.4 3.2 4.1 3.1 5.8 3.7 2.8 3.0 4.1 5.5 4.1 6.3 3.7 3.0 6.8 2.6 6.0 5.5 HAAO ENSG00000162882 "3-hydroxyanthranilate 3,4-dioxygenase" P46952 2 42767089-42792593 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Dioxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 78.7" "Cell line enhanced" "Detected in some" "CACO-2: 8.8;Hep G2: 31.1;REH: 6.5;THP-1: 5.9" "Group enriched" "Detected in all" 5 "liver cancer: 46.5;renal cancer: 13.9" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "myeloid DC: 15.7" "Group enriched" "Detected in many" 5 "dendritic cells: 15.7;granulocytes: 12.6;monocytes: 11.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA036394, HPA042024" Enhanced 150000 "HPA036394: AB_10673131, HPA042024: AB_2677803" "unprognostic (6.97e-3)" "unprognostic (1.86e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-1)" "unprognostic (7.23e-3)" "prognostic favourable (5.77e-4)" "unprognostic (6.20e-2)" "unprognostic (7.58e-2)" "unprognostic (5.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (1.37e-1)" "unprognostic (2.56e-1)" "unprognostic (2.03e-1)" 2.9 1.8 1.6 6.8 1.2 0.7 3.5 0.4 1.1 5.8 11.9 1.9 3.5 5.8 3.6 6.2 2.7 3.2 2.7 2.2 0.9 0.8 10.9 78.7 1.8 2.1 1.4 1.6 5.0 8.6 1.7 1.6 3.8 1.4 6.5 2.9 12.1 1.4 3.1 0.9 1.6 24.5 6.5 1.5 1.8 2.4 1.7 0.9 1.6 2.0 1.3 1.9 4.3 3.2 2.8 15.7 12.6 11.8 0.5 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 3.0 8.8 0.1 0.0 0.1 0.3 0.0 3.1 0.0 0.5 0.0 1.0 3.5 0.0 31.1 0.3 1.2 0.1 1.5 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 1.8 0.0 6.5 0.7 0.1 0.0 0.0 0.1 0.0 0.4 0.7 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 5.7 11.8 12.6 0.0 7.0 0.0 2.2 0.0 0.0 15.7 2.8 0.0 0.0 3.7 0.5 1.8 5.1 0.0 3.5 1.6 1.2 0.4 1.1 0.9 0.8 1.4 1.6 1.4 0.9 HABP2 "FSAP, HABP, HGFAL, PHBP" ENSG00000148702 "Hyaluronan binding protein 2" Q14520 10 113550837-113589602 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 135.4" "Cell line enriched" "Detected in some" 6 "RPTEC TERT1: 33.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 92.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA019518 Uncertain "Secreted to blood" 20206666667 3200000000 "HPA019518: AB_1850467" "unprognostic (3.89e-2)" "unprognostic (6.15e-2)" "unprognostic (1.33e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-1)" "unprognostic (6.92e-2)" "unprognostic (1.01e-1)" "unprognostic (5.86e-3)" "unprognostic (1.67e-1)" "unprognostic (9.78e-2)" "unprognostic (5.10e-2)" "unprognostic (4.77e-2)" "unprognostic (9.18e-3)" "unprognostic (2.62e-3)" "unprognostic (2.11e-1)" "unprognostic (3.22e-1)" "unprognostic (9.05e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.6 0.6 0.3 0.0 0.4 26.4 0.4 0.0 0.0 20.9 135.4 0.2 0.0 0.0 0.0 0.8 11.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 33.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 HACD2 PTPLB ENSG00000206527 "3-hydroxyacyl-CoA dehydratase 2" Q6Y1H2 3 123490820-123585185 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SiHa: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019282 Approved "CAB019282: " "unprognostic (3.04e-2)" "unprognostic (2.51e-1)" "unprognostic (6.11e-2)" "unprognostic (2.65e-3)" "unprognostic (5.36e-2)" "unprognostic (6.04e-2)" "unprognostic (1.32e-2)" "unprognostic (1.95e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "prognostic unfavourable (9.59e-5)" "unprognostic (6.90e-2)" "unprognostic (7.03e-3)" "unprognostic (1.48e-1)" "unprognostic (3.85e-2)" "unprognostic (1.94e-2)" "unprognostic (2.59e-2)" 43.2 9.7 18.0 11.2 30.0 5.7 16.6 20.5 18.7 14.1 20.4 28.6 7.4 21.2 12.4 13.5 18.8 9.9 12.2 9.9 20.7 13.4 20.7 34.3 13.8 14.1 29.4 12.0 13.8 13.4 15.6 12.5 11.1 18.5 22.1 20.4 7.3 15.5 10.2 5.6 23.2 30.8 12.3 24.9 9.6 15.3 13.3 25.7 9.1 16.0 10.5 19.7 10.9 16.6 4.9 6.4 2.4 3.5 2.9 5.3 2.4 19.4 11.0 7.6 5.5 23.9 5.3 28.3 13.9 5.8 14.5 10.5 22.5 17.2 11.2 10.1 13.3 42.5 13.6 17.5 15.3 7.1 4.5 7.8 10.4 17.4 7.8 10.3 7.8 7.3 45.1 7.0 19.7 7.5 1.5 11.2 8.7 15.1 4.9 3.1 9.8 9.8 7.5 8.3 11.9 17.5 12.5 13.4 4.2 64.8 13.8 8.8 14.4 5.4 5.8 15.2 11.4 15.2 13.5 6.7 8.5 9.2 6.8 7.3 8.1 1.5 3.5 2.4 3.6 2.8 5.3 3.4 4.8 4.6 6.4 4.9 4.4 4.3 1.1 2.9 2.2 3.7 5.3 2.4 18.0 30.0 20.5 18.7 20.7 13.4 29.4 12.0 18.5 25.7 HACD3 "B-ind1, HSPC121, PTPLAD1" ENSG00000074696 "3-hydroxyacyl-CoA dehydratase 3" Q9P035 15 65530418-65578352 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014837, HPA060347" Enhanced Enhanced "Endoplasmic reticulum" 27000 "Endoplasmic reticulum" "HPA014837: AB_1855914, HPA060347: " "unprognostic (1.51e-2)" "unprognostic (2.89e-1)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (3.52e-1)" "unprognostic (1.92e-2)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (3.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.57e-1)" "prognostic favourable (3.09e-5)" "unprognostic (3.44e-2)" "unprognostic (5.33e-2)" "unprognostic (1.10e-2)" "unprognostic (2.04e-2)" 9.6 37.4 31.0 7.4 36.0 6.2 33.3 28.6 37.6 18.5 12.5 24.2 10.1 12.2 13.1 19.4 8.4 14.3 14.7 5.9 29.2 44.8 35.0 50.0 12.7 7.2 36.5 26.0 21.7 12.6 22.5 33.9 15.9 45.9 18.5 15.1 17.9 11.6 15.8 3.3 11.7 12.0 12.2 41.5 8.5 29.0 13.9 19.7 8.9 30.7 5.6 8.3 18.8 10.4 13.0 9.0 2.7 6.1 11.7 19.9 11.2 19.6 44.0 49.0 24.4 30.9 18.7 23.2 21.8 18.9 24.8 28.1 33.7 29.5 24.8 19.1 23.6 54.4 78.9 18.2 22.3 13.7 44.0 19.6 22.1 36.8 15.7 24.3 15.1 19.1 13.6 17.0 12.3 24.1 25.7 9.4 40.0 23.4 18.0 19.0 41.7 15.0 20.4 41.5 27.9 35.4 34.2 29.6 26.1 23.5 26.5 24.6 26.9 12.9 19.1 31.6 27.8 15.5 30.2 18.4 54.5 34.9 21.0 23.8 18.9 2.7 3.9 1.2 17.6 5.8 19.9 13.0 16.1 16.6 6.8 13.0 18.9 18.5 0.4 11.7 6.1 9.0 12.4 11.2 31.0 36.0 28.6 34.1 29.2 44.8 36.5 26.0 45.9 19.7 HACD4 "Em:AL662879.1, PTPLAD2" ENSG00000188921 "3-hydroxyacyl-CoA dehydratase 4" Q5VWC8 9 20999515-21031636 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 15.5;HDLM-2: 9.4;TIME: 7.7;U-937: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058666 Uncertain "HPA058666: " "unprognostic (1.71e-1)" "unprognostic (2.58e-2)" "unprognostic (5.47e-2)" "unprognostic (1.70e-2)" "unprognostic (7.66e-2)" "unprognostic (1.87e-2)" "unprognostic (2.21e-1)" "unprognostic (1.28e-2)" "unprognostic (1.11e-4)" "prognostic favourable (3.14e-4)" "unprognostic (8.72e-2)" "unprognostic (1.63e-1)" "prognostic unfavourable (6.77e-4)" "unprognostic (3.89e-3)" "unprognostic (7.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.00e-3)" 4.3 7.9 4.9 9.2 7.1 16.3 10.3 3.3 3.1 8.9 10.1 2.6 1.2 3.2 6.9 5.6 10.7 6.5 7.6 7.5 4.1 3.2 3.3 1.8 24.1 18.2 5.2 1.8 6.5 1.9 4.0 2.3 9.9 3.7 5.9 5.0 6.3 3.6 3.8 1.5 4.7 7.5 11.5 9.6 10.1 5.4 1.8 5.5 19.9 4.1 6.2 7.9 5.1 5.6 1.2 8.4 13.6 8.8 3.0 3.0 3.9 3.7 1.1 0.4 0.1 0.0 0.1 0.1 3.4 15.5 2.8 3.2 0.0 0.0 3.3 1.9 6.5 1.0 0.2 1.4 3.5 9.4 0.1 0.0 1.1 0.0 2.1 2.7 3.0 6.2 6.1 2.5 0.0 0.9 0.0 1.9 0.5 0.1 0.0 3.8 0.8 0.0 0.0 0.0 0.1 0.1 0.4 0.6 0.0 0.8 0.3 0.0 2.8 5.2 7.7 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 11.9 0.1 13.6 7.1 11.4 2.2 8.8 2.0 1.2 2.4 2.5 8.4 1.2 1.7 2.4 10.2 3.0 8.5 0.9 3.0 3.9 4.9 7.1 3.3 3.1 4.1 3.2 5.2 1.8 3.7 5.5 HACE1 KIAA1320 ENSG00000085382 "HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1" Q8IYU2 6 104728093-104859919 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 41.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046071 Supported "Nuclear bodies,Endoplasmic reticulum" "Endoplasmic reticulum" "Nuclear bodies" "HPA046071: " "unprognostic (6.32e-2)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" "unprognostic (1.12e-2)" "unprognostic (3.75e-2)" "unprognostic (3.75e-3)" "unprognostic (1.22e-3)" "unprognostic (4.63e-2)" "unprognostic (7.41e-2)" "unprognostic (1.24e-1)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "prognostic unfavourable (1.17e-5)" "unprognostic (1.12e-2)" "unprognostic (2.06e-1)" "prognostic unfavourable (7.50e-4)" "unprognostic (1.75e-1)" 6.4 5.4 12.7 3.7 16.1 4.3 6.1 15.5 13.1 6.6 4.8 6.8 2.5 3.6 8.5 2.9 8.1 5.4 5.0 5.2 7.5 8.6 9.4 2.9 5.7 3.5 8.8 9.6 6.4 3.8 12.0 7.4 41.9 10.2 6.1 3.3 7.7 6.2 6.9 4.4 4.8 3.6 6.5 9.5 4.1 3.9 14.1 8.9 5.4 7.1 2.7 3.9 6.4 5.8 2.9 2.4 2.2 2.9 2.2 3.9 1.6 3.5 2.5 10.7 13.4 6.4 8.5 12.7 7.2 11.1 4.6 6.9 2.3 2.1 2.0 3.2 5.4 2.4 2.7 4.9 9.7 8.2 6.8 7.1 2.3 3.1 6.4 6.1 2.3 5.7 4.5 5.9 5.0 7.5 6.8 2.3 9.0 2.6 4.5 3.6 4.7 2.4 7.2 12.2 0.8 3.7 6.1 5.8 8.7 3.9 4.1 2.1 2.6 8.4 7.9 3.7 3.1 9.9 6.8 3.3 3.6 6.9 3.9 5.8 6.7 0.0 1.9 2.2 3.7 2.9 3.9 2.9 3.7 3.6 1.9 2.7 3.9 3.0 0.4 2.2 1.5 2.4 1.2 1.6 12.7 16.1 15.5 13.1 7.5 8.6 8.8 9.6 10.2 8.9 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035175 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 98.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Supported Supported Mitochondria 8700000 Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favourable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 36.6 19.5 8.5 15.6 9.2 6.1 41.7 5.4 9.7 15.2 29.7 10.6 9.4 23.3 18.3 13.3 20.5 15.7 12.4 98.3 7.8 8.1 37.2 60.3 10.6 8.8 10.0 7.0 17.1 17.8 9.8 6.8 5.1 9.2 15.6 25.0 11.6 20.4 12.5 64.6 9.0 37.1 19.6 10.2 8.0 19.1 12.6 7.2 40.9 16.1 38.0 13.1 14.2 10.6 18.6 22.6 5.6 10.7 20.2 13.0 8.9 8.8 8.3 18.0 13.1 43.3 13.9 8.7 13.0 19.4 14.2 14.0 5.9 16.7 50.4 7.0 10.7 11.9 23.9 18.1 15.7 15.4 12.5 11.7 15.9 13.2 6.9 24.7 5.5 14.5 9.7 10.0 9.2 9.5 14.5 26.8 16.0 16.1 41.9 9.9 8.5 11.1 32.0 25.2 25.2 15.3 36.1 21.7 12.5 12.6 45.1 12.8 21.5 19.6 5.3 10.0 5.7 14.1 7.1 15.2 17.6 21.9 13.6 16.8 7.7 0.0 6.1 5.6 10.1 7.8 12.5 18.6 11.4 12.1 19.7 15.5 13.0 13.0 0.7 20.2 10.7 22.6 10.0 8.9 8.5 9.2 5.4 9.7 7.8 8.1 10.0 7.0 9.2 7.2 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244726 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria 2700000 Mitochondria "HPA015536: AB_1850473, HPA056070: " "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favourable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 41.6 35.3 18.1 13.1 19.5 17.0 23.9 17.4 16.9 20.2 44.9 26.5 15.7 48.1 21.1 15.3 30.8 20.5 15.1 80.0 15.6 15.5 41.3 71.7 17.7 19.3 21.6 13.1 27.3 37.5 29.8 23.5 21.3 24.8 21.9 32.2 23.6 21.1 16.6 117.5 23.3 66.4 25.1 27.8 24.0 24.1 18.7 19.0 25.2 25.1 41.3 24.6 26.9 18.8 15.3 28.9 12.4 32.2 13.5 17.6 26.0 23.3 20.8 13.7 22.4 54.5 34.1 11.7 18.3 19.8 18.9 16.4 26.3 22.7 15.4 12.0 32.1 14.9 24.0 35.5 17.1 34.5 29.4 23.1 22.1 43.8 18.8 29.1 17.0 34.8 23.3 26.8 26.9 31.6 31.4 31.3 24.3 28.6 12.7 32.6 11.7 40.2 11.7 29.6 33.1 21.6 28.2 9.7 19.3 21.5 22.4 24.8 11.9 28.2 28.9 11.0 16.3 16.4 13.4 10.3 20.3 27.4 17.1 34.5 13.2 8.1 27.7 12.4 12.3 32.2 14.8 15.3 14.2 15.0 28.9 11.2 16.7 15.3 7.4 13.5 28.0 11.0 17.6 26.0 18.1 19.5 17.4 16.9 15.6 15.5 21.6 13.1 24.8 19.0 HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290468 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 126.0;skeletal muscle: 155.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria 1100000 Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favourable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" 23.3 45.5 24.8 11.0 24.7 9.9 16.6 16.6 17.4 13.8 21.4 31.1 19.3 43.6 17.1 16.2 20.6 13.9 12.6 126.0 18.0 20.0 45.8 62.4 12.8 16.1 34.8 18.3 16.2 23.7 19.9 13.1 12.6 27.8 15.8 22.8 19.9 27.2 15.9 155.6 13.2 35.0 20.3 29.5 15.3 19.5 15.8 23.8 10.6 22.4 44.9 14.5 18.5 12.8 20.2 45.2 21.5 49.1 23.8 26.8 33.9 22.7 18.0 12.6 22.5 77.7 43.0 12.7 19.2 29.4 19.8 19.4 21.5 22.2 11.4 13.5 31.4 18.0 20.9 27.1 24.3 25.7 18.2 26.2 10.7 42.0 33.3 21.1 20.1 41.6 44.8 20.5 33.5 36.6 21.9 18.5 41.2 16.7 11.8 40.8 8.7 19.6 13.1 41.6 21.7 40.7 32.4 6.0 20.7 32.9 37.5 50.4 23.2 37.8 25.3 18.7 19.5 17.5 13.8 13.9 20.9 20.1 21.5 33.8 18.5 21.0 49.1 18.9 14.2 43.4 18.1 20.2 19.3 17.6 45.2 14.8 18.0 16.3 21.5 23.8 33.2 15.3 26.8 33.9 24.8 24.7 16.6 17.4 18.0 20.0 34.8 18.3 27.8 23.8 HAGH "GLO2, GLXII, HAGH1" ENSG00000063854 "Hydroxyacylglutathione hydrolase" Q16775 16 1795620-1827194 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 91.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043041, HPA061143" Approved 3000000 "HPA043041: , HPA061143: " "unprognostic (3.11e-1)" "prognostic favourable (5.82e-5)" "unprognostic (2.54e-1)" "unprognostic (1.93e-2)" "unprognostic (5.84e-2)" "unprognostic (1.54e-1)" "prognostic favourable (5.33e-6)" "unprognostic (5.78e-3)" "unprognostic (3.34e-2)" "unprognostic (7.69e-2)" "unprognostic (3.34e-3)" "unprognostic (1.60e-1)" "prognostic favourable (1.81e-6)" "unprognostic (1.20e-1)" "unprognostic (6.24e-2)" "unprognostic (7.18e-3)" "prognostic favourable (5.19e-4)" 14.8 36.9 24.9 7.8 26.7 26.2 16.4 26.8 35.3 9.7 12.9 13.6 19.6 17.6 6.8 13.0 11.7 11.8 9.9 50.9 28.0 24.5 38.8 91.4 14.5 8.5 23.2 24.5 6.3 24.6 17.1 19.7 9.2 18.5 12.4 9.5 11.9 12.5 16.2 67.1 11.0 17.1 11.7 20.7 10.1 13.1 33.8 13.7 7.4 14.1 18.3 7.2 9.7 18.2 13.7 28.9 27.7 36.5 10.9 18.3 12.5 11.4 17.4 15.8 17.8 13.8 5.5 14.2 14.4 13.4 22.3 18.0 8.9 10.0 2.4 29.7 12.3 12.6 14.9 14.4 6.7 23.8 24.0 4.4 17.8 25.5 19.9 5.8 24.2 6.7 31.1 11.1 7.6 19.1 5.8 21.6 7.0 18.9 14.9 12.5 6.0 16.1 12.6 9.9 27.0 28.6 5.2 21.2 18.3 15.8 20.3 31.0 14.9 19.4 14.5 6.8 8.4 14.2 16.5 24.5 23.1 7.1 11.6 5.4 10.8 14.4 15.3 27.7 12.6 25.8 9.2 13.7 16.2 12.9 13.7 12.4 15.8 13.2 13.5 10.9 36.5 28.9 18.3 12.5 24.9 26.7 26.8 35.3 28.0 24.5 23.2 24.5 18.5 13.7 HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood: 29.5;liver: 96.8;skin 1: 26.9" "Cell line enhanced" "Detected in some" "BEWO: 3.1;NB-4: 3.9;THP-1: 15.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 23.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "basophil: 20.1;neutrophil: 29.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 29.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038547, HPA038548" Enhanced Approved Cytosol 67000 Cytosol "HPA038547: AB_10669541, HPA038548: AB_10673175" "unprognostic (3.39e-1)" "unprognostic (4.46e-2)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (5.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-3)" "unprognostic (1.89e-2)" "unprognostic (3.74e-1)" "unprognostic (4.03e-2)" "unprognostic (2.87e-2)" 0.5 0.0 0.1 1.1 0.3 4.4 0.9 0.1 0.3 0.3 0.2 0.1 0.1 0.1 1.1 0.3 0.5 0.2 0.3 0.2 0.1 0.0 0.2 96.8 1.7 2.3 0.5 0.1 0.3 0.5 0.0 7.4 0.4 0.2 0.2 0.0 0.1 0.2 0.1 0.2 26.9 0.2 0.2 0.3 2.7 0.1 0.2 0.2 0.1 0.2 0.9 1.3 0.2 0.5 0.0 1.4 29.5 6.3 0.3 0.1 1.6 0.5 0.0 0.2 0.1 0.0 0.0 3.1 0.0 0.2 0.1 0.2 0.0 0.1 0.9 0.0 0.0 0.2 0.3 0.1 0.1 0.2 0.5 0.4 0.2 0.0 0.0 0.6 0.6 0.0 0.9 0.4 0.4 0.3 0.0 0.2 0.1 0.0 0.2 3.9 1.3 0.6 0.2 0.1 0.1 0.1 0.8 0.2 0.4 0.4 0.1 0.0 0.0 15.1 0.2 0.1 0.2 0.2 0.2 0.6 0.7 0.2 0.0 2.4 0.0 20.1 6.3 0.9 0.0 2.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 29.5 0.3 5.1 0.1 0.1 1.6 0.1 0.3 0.1 0.3 0.1 0.0 0.5 0.1 0.2 0.2 HAO1 "GOX, GOX1" ENSG00000101323 "Hydroxyacid oxidase 1" Q9UJM8 20 7882981-7940474 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 594 "liver: 121.8" "Cell line enhanced" "Detected in some" "HL-60: 1.6;RH-30: 2.2;U-251 MG: 2.4" "Cancer enriched" "Detected in some" 184 "liver cancer: 93.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049552 Enhanced 200000 "HPA049552: " "unprognostic (4.88e-2)" "unprognostic (2.87e-3)" "unprognostic (1.08e-2)" "unprognostic (1.25e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 121.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.8 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HARS USH3B ENSG00000170445 "Histidyl-tRNA synthetase" P12081 5 140673904-140691862 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Charcot-Marie-Tooth disease, Deafness, Disease mutation, Neurodegeneration, Neuropathy, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036539 Approved Enhanced Cytosol 52000 Cytosol "HPA036539: AB_10669796" "unprognostic (9.35e-2)" "unprognostic (9.95e-2)" "unprognostic (1.62e-3)" "unprognostic (1.65e-2)" "unprognostic (2.33e-1)" "unprognostic (8.57e-2)" "prognostic unfavourable (1.96e-7)" "unprognostic (6.50e-2)" "unprognostic (1.46e-1)" "unprognostic (3.82e-2)" "unprognostic (1.28e-2)" "unprognostic (2.40e-1)" "unprognostic (3.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.36e-1)" 22.4 24.5 28.5 21.1 35.5 18.1 21.0 41.1 46.3 20.6 22.7 20.0 23.6 17.4 21.6 23.5 26.9 23.7 17.5 25.1 29.5 35.9 20.6 34.2 16.7 22.4 36.9 33.0 24.7 25.2 29.5 38.7 15.0 38.2 21.7 24.8 13.6 22.1 27.9 27.1 33.9 16.4 28.0 21.0 18.3 18.8 16.6 23.5 17.6 19.4 20.3 28.5 19.9 20.9 16.8 22.1 10.7 22.9 25.2 29.4 23.4 20.5 30.0 18.1 39.5 23.1 25.1 19.1 33.1 23.9 38.3 35.9 54.7 17.4 27.4 29.2 37.1 21.6 27.5 53.3 36.1 23.2 34.0 19.7 39.0 34.6 28.7 30.9 16.9 26.6 16.7 41.7 23.8 38.4 17.2 22.7 39.8 35.3 22.0 28.8 14.2 19.8 20.3 26.3 22.3 30.8 26.2 28.5 27.5 27.4 40.0 26.1 29.5 17.4 32.0 36.0 13.8 20.2 44.6 22.9 27.2 27.7 27.3 26.0 24.5 6.7 14.1 10.7 29.4 20.8 26.3 16.8 25.8 27.3 22.1 14.8 28.2 26.9 4.3 25.2 22.9 15.6 22.1 23.4 28.5 35.5 41.1 46.3 29.5 35.9 36.9 33.0 38.2 23.5 HARS2 "HARSL, HARSR, HO3" ENSG00000112855 "Histidyl-tRNA synthetase 2, mitochondrial" P49590 5 140691426-140699318 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035941 Approved Approved Cytosol "Intracellular and membrane" Cytosol "HPA035941: AB_10671237" "prognostic unfavourable (6.49e-4)" "unprognostic (3.15e-2)" "prognostic favourable (6.19e-4)" "unprognostic (1.79e-2)" "unprognostic (1.78e-1)" "unprognostic (8.30e-3)" "prognostic unfavourable (2.92e-4)" "unprognostic (7.77e-2)" "unprognostic (1.88e-1)" "unprognostic (5.26e-2)" "unprognostic (1.58e-1)" "unprognostic (2.68e-2)" "unprognostic (1.85e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (1.31e-2)" 17.1 23.8 14.2 22.9 19.4 13.4 25.0 24.7 19.0 15.0 21.6 16.6 19.7 17.7 20.2 16.9 16.7 14.9 16.7 25.2 15.7 12.6 19.6 14.5 21.4 25.2 15.5 11.2 17.4 13.6 22.9 21.1 15.8 14.4 14.3 24.4 16.4 16.4 15.4 32.7 18.3 17.2 15.6 12.9 18.5 17.9 15.1 15.6 16.5 15.8 13.9 18.8 20.6 18.4 13.7 12.0 22.9 15.0 22.8 17.6 9.7 10.7 24.4 10.6 27.2 12.1 16.0 17.5 14.0 16.0 19.6 17.2 22.4 13.6 13.7 22.6 15.4 13.7 14.6 26.2 18.2 13.8 12.0 10.0 23.4 14.7 11.6 13.4 14.7 15.0 17.8 19.1 21.7 14.1 9.2 13.0 19.0 13.8 13.1 16.6 12.2 15.5 13.4 10.8 13.8 18.4 25.3 14.7 21.2 20.2 32.9 27.6 29.0 13.3 17.2 17.7 9.8 9.8 18.3 12.8 18.7 13.2 13.9 15.4 17.6 22.9 10.5 21.3 16.2 15.0 17.5 13.7 15.6 16.2 12.0 12.5 16.4 17.6 12.1 22.8 11.4 9.5 15.3 9.7 14.2 19.4 24.7 19.0 15.7 12.6 15.5 11.2 14.4 15.6 HAS1 HAS ENSG00000105509 "Hyaluronan synthase 1" Q92839 19 51713112-51723994 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.7;lymphoid tissue: 13.7;ovary: 23.6" "Cell line enriched" "Detected in some" 4 "U-87 MG: 49.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "eosinophil: 5.9;neutrophil: 1.6" "Lineage enriched" "Detected in single" 15 "granulocytes: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA067602 Approved Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA067602: " "unprognostic (3.56e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "unprognostic (5.26e-4)" "unprognostic (7.17e-3)" "unprognostic (7.05e-2)" "unprognostic (1.02e-1)" "unprognostic (5.49e-4)" "unprognostic (4.80e-2)" "unprognostic (1.99e-2)" "unprognostic (8.43e-2)" "unprognostic (1.72e-1)" "unprognostic (2.30e-11)" "unprognostic (9.12e-4)" "unprognostic (8.99e-2)" "unprognostic (3.73e-4)" "unprognostic (2.43e-2)" 23.7 0.5 0.6 13.7 1.3 2.8 1.0 1.5 1.9 0.6 1.2 0.4 1.1 0.1 0.8 2.5 1.3 5.8 5.5 5.9 1.4 2.0 0.3 0.6 4.5 0.3 0.6 0.3 23.6 2.2 0.0 0.3 0.3 0.6 0.4 0.5 1.0 0.3 1.2 2.1 2.7 4.0 3.6 0.9 0.7 0.7 0.9 0.3 0.3 0.3 0.8 0.3 1.8 0.3 0.1 0.1 5.9 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 11.7 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 49.8 0.0 0.1 0.0 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.6 0.0 0.0 0.1 0.0 0.1 0.6 1.3 1.5 1.7 1.4 2.0 0.6 0.3 0.6 0.3 HAS2 ENSG00000170961 "Hyaluronan synthase 2" Q92819 8 121612116-121641390 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.8" "Group enriched" "Detected in some" 4 "HBF TERT88: 33.9;hTEC/SVTERT24-B: 32.6;LHCN-M2: 43.3;U-138 MG: 85.2;U-251 MG: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052060 Approved "Nuclear speckles" "Nuclear speckles" "HPA052060: " "unprognostic (7.01e-2)" "unprognostic (1.34e-2)" "unprognostic (4.07e-2)" "unprognostic (4.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.57e-3)" "unprognostic (3.44e-2)" "unprognostic (1.34e-1)" "unprognostic (8.19e-3)" "unprognostic (1.24e-1)" "unprognostic (1.66e-7)" "unprognostic (1.47e-3)" "unprognostic (3.67e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-3)" 22.8 0.9 1.6 9.1 2.4 0.0 5.5 0.8 1.7 4.0 8.5 2.0 0.0 2.6 1.5 2.5 4.8 3.9 7.7 8.3 1.7 1.7 1.2 2.7 6.5 4.5 1.8 0.6 1.2 1.8 0.3 0.7 2.1 5.7 4.3 5.6 2.7 1.9 0.1 2.7 3.8 9.5 3.7 4.2 0.3 2.3 3.2 2.6 0.4 1.7 5.5 2.1 5.7 1.4 0.0 0.2 0.7 0.2 0.3 0.1 0.0 0.0 0.5 0.0 0.0 1.0 2.5 0.0 4.8 3.6 6.3 11.0 0.0 0.0 0.0 0.0 4.3 0.8 0.0 0.0 33.9 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 6.7 0.0 32.6 3.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.7 0.0 5.6 0.0 0.0 0.4 0.0 0.1 2.0 0.0 1.1 0.0 0.0 0.0 85.2 0.3 7.9 25.2 0.0 0.0 0.0 1.8 0.0 1.7 0.5 0.2 0.2 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.7 0.3 0.2 0.2 0.1 0.0 1.6 2.4 0.8 1.7 1.7 1.7 1.8 0.6 5.7 2.6 HAS3 ENSG00000103044 "Hyaluronan synthase 3" O00219 16 69105564-69118719 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 22.6;urinary bladder: 22.9" "Cell line enhanced" "Detected in some" "HaCaT: 14.1;PC-3: 75.1;RT4: 29.7" "Group enriched" "Detected in many" 8 "cervical cancer: 17.1;head and neck cancer: 44.9;lung cancer: 23.3;urothelial cancer: 31.1" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031554, CAB033850" Supported Approved Microtubules Microtubules "CAB033850: AB_2116418, HPA031554: AB_10670703" "unprognostic (3.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (7.59e-3)" "unprognostic (2.86e-3)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (1.77e-1)" "prognostic unfavourable (5.36e-4)" "unprognostic (2.46e-1)" "unprognostic (3.27e-3)" "unprognostic (3.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (3.40e-3)" 0.4 0.2 0.4 0.4 1.0 0.3 5.5 1.1 1.3 3.3 3.7 0.4 0.4 1.9 0.8 1.1 22.6 0.7 3.5 2.4 0.6 0.6 1.2 0.7 18.0 0.4 0.4 0.4 0.9 2.2 0.1 1.0 3.3 1.1 3.5 2.3 0.6 7.6 2.1 0.6 5.7 2.1 1.4 0.4 0.4 9.0 2.0 0.4 0.5 4.0 11.7 11.1 22.9 13.6 1.5 1.2 2.2 1.4 0.4 2.0 1.1 0.9 4.7 0.2 0.2 0.1 0.1 1.8 0.3 0.1 0.2 0.1 1.0 2.4 0.2 0.5 0.1 14.1 0.7 8.4 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 2.3 0.3 0.8 0.1 0.0 0.1 0.0 0.5 0.3 0.1 4.2 75.1 0.5 0.0 0.0 7.7 29.7 5.3 0.2 0.5 0.0 0.0 0.2 0.2 0.1 0.2 0.2 8.2 0.4 0.3 0.2 0.0 0.3 0.0 0.1 0.8 1.4 2.2 1.4 0.7 1.3 0.7 1.1 0.5 1.2 1.5 2.0 0.7 0.5 0.4 1.1 1.0 1.5 1.1 0.4 1.0 1.1 1.3 0.6 0.6 0.4 0.4 1.1 0.4 HASPIN GSG2 ENSG00000177602 "Histone H3 associated protein kinase" Q8TF76 17 3723903-3726699 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 7.5;lymphoid tissue: 26.7;testis: 26.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA027422, HPA030698" Approved Supported Nucleoplasm Nucleoplasm "HPA027422: AB_10601812, HPA030698: " "unprognostic (1.15e-2)" "unprognostic (2.78e-2)" "unprognostic (7.06e-2)" "unprognostic (2.14e-2)" "unprognostic (8.05e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-4)" "unprognostic (1.57e-2)" "unprognostic (6.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "unprognostic (3.82e-3)" "unprognostic (0.00e+0)" "unprognostic (5.65e-3)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" 1.2 0.3 0.3 11.8 0.6 7.5 1.8 0.5 0.3 0.5 1.5 0.2 0.0 2.2 0.3 0.4 2.8 0.6 1.3 0.6 0.2 0.2 0.8 0.4 2.6 5.8 0.4 0.0 0.4 0.5 0.0 0.3 1.3 0.2 0.7 1.5 0.2 1.0 0.0 1.2 0.9 3.6 0.4 1.2 4.9 1.7 26.7 0.3 26.7 0.7 1.7 7.3 0.8 1.0 2.8 1.5 2.1 0.6 0.0 1.2 0.4 7.5 8.2 7.6 8.6 0.5 1.0 6.4 6.9 5.3 13.7 13.5 6.4 3.1 18.5 4.0 3.8 12.3 13.7 6.7 13.1 0.1 11.5 9.2 6.7 3.8 0.3 5.3 9.5 0.6 0.5 10.3 6.4 6.2 8.1 16.3 6.9 3.9 10.7 3.1 6.7 5.7 11.1 9.6 5.0 2.0 5.3 3.1 4.5 6.1 4.2 2.4 4.2 5.0 3.2 6.1 7.0 6.8 12.1 3.1 3.5 9.0 3.6 7.7 7.3 0.4 0.6 2.1 0.2 0.5 0.2 0.7 0.8 0.0 1.1 2.8 1.2 0.2 0.2 0.0 0.0 1.5 0.1 0.4 0.3 0.6 0.5 0.3 0.2 0.2 0.4 0.0 0.2 0.3 HAT1 KAT1 ENSG00000128708 "Histone acetyltransferase 1" O14929 2 171922448-171983682 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036788, CAB037191" Supported Supported Nucleoplasm Nucleoplasm "CAB037191: AB_477070, HPA036788: AB_10672267" "unprognostic (1.76e-1)" "unprognostic (1.01e-2)" "unprognostic (7.39e-3)" "unprognostic (8.24e-3)" "unprognostic (2.76e-1)" "unprognostic (1.54e-1)" "prognostic unfavourable (5.72e-5)" "unprognostic (2.71e-2)" "unprognostic (9.08e-3)" "unprognostic (3.69e-2)" "unprognostic (1.56e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (6.89e-2)" "unprognostic (1.80e-1)" "unprognostic (3.97e-2)" "unprognostic (6.69e-2)" 24.3 23.7 14.3 20.8 21.4 30.9 25.7 18.4 16.7 17.6 18.2 14.0 17.7 11.8 20.7 15.6 21.3 17.7 14.8 26.2 16.7 13.0 27.5 22.1 18.8 26.9 21.2 12.9 21.8 23.0 22.3 32.2 21.1 21.4 20.8 19.3 13.1 25.5 15.6 53.9 18.6 15.8 22.9 20.5 22.5 20.2 15.9 21.5 35.4 26.1 31.8 27.8 22.1 16.9 21.0 16.0 29.9 32.1 25.9 28.1 19.2 34.0 16.3 28.8 26.3 15.3 15.9 20.3 35.6 23.8 39.3 41.1 37.7 23.6 38.2 23.1 21.5 27.1 31.1 29.1 60.8 21.5 30.9 33.7 26.9 34.0 7.5 42.5 21.2 9.5 16.9 51.8 17.4 24.8 34.8 25.1 44.6 23.8 33.3 38.9 23.9 17.1 26.7 36.3 25.9 23.4 34.4 18.4 15.1 29.8 16.7 30.2 23.2 43.2 12.5 35.4 27.3 29.7 35.8 11.0 25.4 45.0 23.8 30.5 30.5 23.8 21.1 29.9 20.8 24.5 25.8 21.0 22.1 21.3 16.0 18.4 22.2 24.2 24.0 25.9 32.1 8.2 28.1 19.2 14.3 21.4 18.4 16.7 16.7 13.0 21.2 12.9 21.4 21.5 HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123078 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria "Intracellular and membrane" Mitochondria "HPA002946: AB_1079041" "prognostic unfavourable (8.69e-5)" "unprognostic (6.89e-3)" "unprognostic (8.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.44e-2)" "prognostic unfavourable (1.35e-5)" "unprognostic (9.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (1.60e-1)" "prognostic favourable (6.17e-8)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-2)" 10.6 14.2 8.8 9.0 12.7 11.8 9.6 11.0 17.7 6.7 15.5 7.4 8.0 17.2 8.5 5.5 15.8 6.9 9.8 36.9 8.4 8.3 15.9 19.0 9.5 10.1 8.2 11.1 10.0 11.4 11.5 10.0 12.8 10.6 7.8 15.2 9.3 12.8 8.0 41.6 13.8 14.4 10.4 6.3 12.3 12.2 10.5 6.0 10.3 10.8 16.4 11.8 11.4 17.3 18.1 28.4 13.3 29.7 8.4 11.1 8.7 23.2 26.8 12.5 12.0 11.8 11.4 13.3 23.5 17.9 29.7 25.5 31.1 17.0 14.5 12.1 18.8 21.6 25.9 22.4 29.0 13.5 20.3 14.5 34.4 15.5 20.9 15.8 17.7 11.1 17.5 28.2 19.3 21.0 26.8 16.8 19.9 31.5 11.4 12.8 22.7 29.0 11.2 25.2 28.4 20.0 18.3 9.1 10.7 23.4 25.5 15.0 19.7 11.4 20.6 19.3 10.4 49.2 20.0 12.4 12.6 19.2 15.5 12.7 18.4 10.1 22.5 13.3 9.9 29.7 9.5 18.1 9.7 8.9 28.4 15.5 8.5 11.1 6.2 8.4 24.8 25.9 10.4 8.7 8.8 12.7 11.0 17.7 8.4 8.3 8.2 11.1 10.6 6.0 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052188-32101856 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 107.1;lymphoid tissue: 72.6" "Group enriched" "Detected in some" 8 "THP-1: 22.6;U-937: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 50.8;eosinophil: 62.5;intermediate monocyte: 96.5;myeloid DC: 31.6;neutrophil: 73.0;non-classical monocyte: 107.1" "Group enriched" "Detected in many" 15 "dendritic cells: 31.6;granulocytes: 73.0;monocytes: 107.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005195, HPA063768" Approved Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB005195: AB_631619, HPA063768: " "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavourable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 12.3 5.8 5.9 40.8 13.1 20.8 4.0 1.8 5.3 3.0 5.8 6.1 0.9 5.9 2.5 5.7 3.1 5.9 6.5 8.8 6.0 3.7 4.0 7.9 20.9 50.3 11.2 1.2 3.4 2.8 0.7 2.9 8.8 8.0 3.8 5.9 3.1 4.1 1.9 3.1 2.8 7.8 10.2 9.1 72.6 3.7 2.6 8.2 5.8 3.3 1.2 16.4 9.4 3.5 4.7 31.6 73.0 107.1 1.1 0.1 40.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 22.6 0.0 0.0 0.1 0.0 0.0 0.6 0.1 3.3 0.0 64.8 0.0 0.5 50.8 62.5 0.1 96.5 0.1 4.7 0.1 0.1 31.6 3.7 0.1 0.0 73.0 1.1 107.1 2.8 0.1 40.2 5.9 13.1 1.8 5.3 6.0 3.7 11.2 1.2 8.0 8.2 HDAC1 "GON-10, HD1, RPD3L1" ENSG00000116478 "Histone deacetylase 1" Q13547 1 32292086-32333635 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005017, HPA029693, CAB068191" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB005017: AB_2248344, CAB068191: , HPA029693: AB_10601659" "unprognostic (2.51e-2)" "unprognostic (9.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.57e-3)" "prognostic unfavourable (5.76e-7)" "unprognostic (9.57e-2)" "unprognostic (5.02e-2)" "unprognostic (3.47e-2)" "unprognostic (7.06e-2)" "unprognostic (4.44e-2)" "prognostic unfavourable (1.04e-5)" "unprognostic (6.86e-2)" "unprognostic (3.78e-1)" "unprognostic (7.16e-2)" "unprognostic (1.72e-1)" 13.8 22.8 12.8 33.5 14.8 15.0 21.1 5.1 13.0 21.9 35.7 16.0 34.8 22.2 24.6 17.5 40.6 21.0 43.8 12.4 12.5 8.5 21.1 21.5 17.2 33.3 14.7 8.6 27.7 20.5 17.2 27.1 24.4 12.2 25.2 33.9 18.0 27.8 31.3 6.6 16.9 32.7 22.1 13.3 32.6 27.8 20.0 16.7 59.4 36.8 21.2 51.1 26.0 25.1 47.7 32.1 59.8 44.6 42.4 49.2 54.7 29.5 18.0 11.6 23.1 6.8 8.1 24.2 20.9 23.5 28.1 26.0 33.0 53.3 45.6 38.9 23.1 34.6 35.7 28.5 31.2 42.6 35.5 31.4 21.7 25.3 16.1 55.6 45.6 14.7 15.7 21.7 14.4 21.3 41.1 18.2 12.3 22.5 63.3 31.3 26.9 46.2 43.8 27.6 20.3 30.4 42.8 9.1 11.5 35.0 23.6 44.0 27.8 43.3 24.6 18.7 22.0 5.7 51.0 11.1 23.8 62.5 15.4 46.2 24.3 37.0 27.7 59.8 43.2 35.5 35.4 47.7 42.4 46.1 32.1 44.3 49.2 45.7 19.9 42.4 44.6 20.1 42.5 54.7 12.8 14.8 5.1 13.0 12.5 8.5 14.7 8.6 12.2 16.7 HDAC10 DKFZP761B039 ENSG00000100429 "Histone deacetylase 10" Q969S8 22 50245183-50251405 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, DNA damage, DNA recombination, DNA repair" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB045977 Supported "CAB045977: AB_11124034" "unprognostic (1.53e-1)" "prognostic favourable (4.46e-4)" "unprognostic (1.43e-2)" "prognostic favourable (2.45e-5)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (6.15e-3)" "unprognostic (5.48e-2)" "unprognostic (3.28e-1)" "unprognostic (2.56e-2)" "prognostic favourable (9.25e-4)" "unprognostic (4.93e-2)" "prognostic unfavourable (4.74e-11)" "unprognostic (2.21e-2)" "unprognostic (2.52e-2)" "unprognostic (1.43e-2)" "unprognostic (1.38e-3)" 8.9 9.3 10.1 14.7 10.3 16.9 6.8 10.9 8.8 8.6 13.9 4.7 14.6 12.9 7.7 13.5 10.2 7.9 13.1 4.0 8.4 6.1 11.4 15.1 8.2 12.5 4.9 8.8 7.8 15.0 6.4 13.2 7.0 6.1 10.2 3.7 8.8 18.6 12.9 9.2 12.1 14.2 7.1 4.4 17.1 14.2 2.4 4.7 16.1 9.3 7.6 19.2 8.2 7.7 1.1 3.1 5.4 4.2 1.1 1.9 2.5 4.1 2.3 0.6 3.4 3.0 2.3 7.6 2.7 2.4 1.6 0.9 4.3 4.5 2.7 3.9 2.1 6.9 1.4 4.1 0.3 3.4 3.9 5.8 6.1 7.2 5.2 6.8 18.9 4.9 3.0 1.5 0.9 2.9 4.0 4.1 1.4 12.8 3.8 17.0 1.4 5.1 9.1 2.2 16.7 2.5 7.0 1.8 4.5 2.8 1.0 4.8 7.8 11.0 4.7 2.7 3.9 4.6 1.6 5.1 1.7 2.3 4.4 4.3 2.1 0.8 4.0 5.4 1.9 4.2 1.6 1.0 0.9 1.2 3.1 1.1 0.8 1.0 2.0 1.1 2.3 2.7 1.6 2.5 10.1 10.3 10.9 8.8 8.4 6.1 4.9 8.8 6.1 4.7 HDAC2 "RPD3, YAF1" ENSG00000196591 "Histone deacetylase 2" Q92769 6 113933028-114011308 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005054, HPA011727" Supported Enhanced Nucleoplasm Nucleoplasm "CAB005054: AB_562295, HPA011727: AB_1850540" "prognostic unfavourable (7.07e-4)" "unprognostic (1.44e-1)" "unprognostic (2.67e-1)" "unprognostic (2.56e-2)" "unprognostic (2.61e-2)" "unprognostic (1.89e-2)" "prognostic unfavourable (5.39e-10)" "unprognostic (2.03e-1)" "unprognostic (2.63e-2)" "unprognostic (9.00e-2)" "unprognostic (2.01e-1)" "unprognostic (3.92e-1)" "unprognostic (1.84e-2)" "unprognostic (1.96e-1)" "unprognostic (2.42e-1)" "unprognostic (9.80e-2)" "unprognostic (3.51e-1)" 25.8 33.8 25.8 30.1 31.3 34.9 58.7 32.8 36.5 32.1 30.7 25.6 32.2 22.0 38.7 36.7 36.3 32.7 23.3 27.6 26.5 26.9 31.6 22.2 29.9 41.5 29.6 26.5 39.2 31.5 31.7 45.1 38.1 27.9 32.1 36.1 17.5 29.3 39.0 33.9 30.8 26.1 36.1 31.1 30.7 29.9 47.4 27.4 64.0 35.1 31.3 32.5 33.1 47.3 27.0 35.7 28.2 32.6 26.3 32.6 24.3 24.2 16.7 78.2 44.9 20.2 23.0 32.8 28.9 23.7 34.2 41.0 44.3 17.9 20.0 24.2 26.0 19.1 53.0 29.3 57.6 28.5 36.6 48.2 21.7 25.6 26.9 48.9 21.8 18.6 19.7 36.4 34.2 39.8 62.0 20.4 56.5 20.3 43.8 44.3 44.2 23.1 29.8 39.0 18.4 35.3 29.3 52.3 44.4 22.9 21.6 24.1 15.7 57.1 32.1 21.8 25.1 22.8 47.9 16.2 21.3 47.9 18.5 47.2 36.9 23.1 27.6 28.2 21.1 26.6 28.1 27.0 25.9 22.7 35.7 22.3 32.6 29.7 16.3 26.3 32.6 30.9 24.5 24.3 25.8 31.3 32.8 36.5 26.5 26.9 29.6 26.5 27.9 27.4 HDAC3 "HD3, RPD3, RPD3-2" ENSG00000171720 "Histone deacetylase 3" O15379 5 141620876-141636870 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005583, HPA052052, CAB072336" Supported Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "CAB005583: AB_562296, CAB072336: , HPA052052: " "unprognostic (6.65e-2)" "unprognostic (1.96e-1)" "prognostic favourable (3.39e-4)" "unprognostic (1.17e-1)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-2)" "unprognostic (3.16e-1)" "unprognostic (5.56e-2)" "unprognostic (2.45e-2)" "prognostic favourable (3.95e-4)" "unprognostic (1.12e-1)" "prognostic unfavourable (2.65e-6)" "unprognostic (1.85e-1)" "unprognostic (1.63e-2)" "unprognostic (2.28e-3)" "unprognostic (2.17e-1)" 15.9 28.8 19.6 12.2 17.6 18.1 18.6 22.6 20.8 15.6 14.1 11.2 13.1 10.6 17.3 17.6 22.8 16.3 14.0 16.8 18.0 8.9 14.5 23.3 24.4 36.4 13.4 14.2 17.3 24.7 20.9 17.3 14.3 18.8 13.6 14.4 13.6 17.5 13.7 24.5 26.7 15.2 17.2 10.8 20.1 15.5 11.9 12.6 18.5 14.4 9.6 23.7 17.5 17.0 22.1 46.7 16.4 22.6 14.1 23.1 16.9 21.1 14.3 26.6 40.4 25.8 20.6 17.3 15.4 33.9 35.0 50.2 30.7 18.1 30.7 20.0 20.0 18.3 26.8 36.1 43.4 26.2 28.8 24.0 13.2 17.4 18.2 28.9 22.0 17.5 23.3 20.3 26.4 22.5 23.4 16.4 22.1 20.0 32.0 25.0 23.5 11.4 23.2 27.9 22.1 18.7 21.3 22.3 18.1 20.4 21.2 25.4 22.6 18.3 11.3 21.7 13.6 16.6 25.2 13.4 16.4 28.9 18.3 27.5 18.6 13.2 22.4 16.4 15.9 22.6 20.8 22.1 19.8 19.2 46.7 20.1 21.7 18.0 9.5 14.1 19.0 23.9 23.1 16.9 19.6 17.6 22.6 20.8 18.0 8.9 13.4 14.2 18.8 12.6 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 54.6" "Cell line enhanced" "Detected in many" "MOLT-4: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 10.5;classical monocyte: 7.4;neutrophil: 28.3" "Group enriched" "Detected in many" 8 "granulocytes: 28.3;monocytes: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004431, HPA048723" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" "Nuclear speckles" "Nucleoplasm, Cytosol" "CAB004431: AB_627706, HPA048723: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (6.33e-4)" "prognostic favourable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 7.9 6.8 6.1 6.8 5.2 17.1 4.6 6.4 12.3 11.3 21.4 4.6 4.3 2.5 10.2 6.4 8.8 9.0 24.6 5.2 5.0 6.0 3.2 3.1 4.2 4.3 6.1 5.4 8.5 5.8 4.9 8.3 2.5 5.2 7.5 4.8 8.3 3.7 7.3 54.6 6.9 6.5 15.8 4.2 5.4 7.0 8.1 4.3 6.5 4.8 13.2 5.6 10.2 4.6 0.5 1.7 28.3 7.4 2.1 1.2 0.4 4.3 4.3 5.5 6.6 3.1 5.3 6.5 4.5 3.1 3.6 3.4 2.0 7.8 2.0 1.8 3.9 4.3 3.8 1.8 1.8 12.0 2.0 3.2 5.3 6.3 4.2 4.9 2.9 3.6 4.6 6.6 5.3 3.8 4.5 4.6 1.7 5.3 31.6 6.7 4.3 2.2 8.2 10.4 3.2 4.1 5.5 4.4 7.8 6.3 2.8 11.1 1.5 13.4 6.1 4.2 0.3 7.2 6.1 3.3 3.1 3.9 6.1 6.8 8.3 10.5 7.4 1.1 0.9 2.4 1.1 0.5 0.9 0.8 0.8 0.5 0.5 1.0 28.3 2.1 1.0 1.7 1.2 0.4 6.1 5.2 6.4 7.5 5.0 6.0 6.1 5.4 5.2 4.3 HDAC5 "FLJ90614, KIAA0600, NY-CO-9" ENSG00000108840 "Histone deacetylase 5" Q9UQL6 17 44076746-44123702 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019400, HPA030991" Approved Supported "Nuclear speckles,Golgi apparatus,Cytosol" "Nuclear speckles" "Golgi apparatus, Cytosol" "CAB019400: AB_2116626, HPA030991: AB_10795286" "unprognostic (1.30e-2)" "prognostic favourable (6.14e-4)" "unprognostic (6.65e-2)" "unprognostic (8.06e-2)" "unprognostic (3.49e-1)" "unprognostic (3.52e-2)" "prognostic unfavourable (3.12e-5)" "unprognostic (8.80e-3)" "unprognostic (3.80e-2)" "unprognostic (2.37e-2)" "unprognostic (4.91e-3)" "unprognostic (4.30e-1)" "prognostic favourable (3.30e-5)" "unprognostic (1.51e-2)" "unprognostic (3.11e-1)" "unprognostic (6.00e-2)" "unprognostic (1.76e-2)" 15.6 17.6 24.9 7.9 15.8 13.2 18.1 35.9 25.8 16.5 8.8 19.6 9.5 8.4 15.0 11.9 20.1 16.9 11.3 24.4 22.1 24.2 8.6 6.3 13.6 8.8 24.7 22.1 24.5 16.1 28.2 17.5 23.0 19.3 13.6 5.5 11.7 14.2 11.9 42.6 34.0 9.7 12.4 20.5 13.8 9.3 10.3 18.1 7.6 15.0 9.8 8.2 14.9 20.4 7.6 9.4 17.9 13.6 3.5 4.9 5.0 3.5 2.3 6.4 1.5 12.4 9.7 23.1 9.6 24.0 4.8 7.9 5.1 3.8 5.6 3.9 22.8 2.9 7.5 4.1 2.0 8.7 12.2 10.9 7.7 11.7 5.3 3.5 15.4 13.7 7.1 5.5 6.9 3.9 8.1 11.4 27.8 2.7 5.8 10.7 7.0 5.5 22.5 17.9 14.4 0.5 1.6 16.7 8.8 2.8 11.8 13.0 16.8 20.7 2.1 12.1 7.8 2.8 4.8 18.8 15.7 6.7 7.0 4.4 5.7 7.1 7.3 7.7 4.9 11.6 3.5 6.6 3.9 4.9 9.4 7.6 4.1 3.5 17.9 3.5 13.6 8.3 3.5 5.0 24.9 15.8 35.9 25.8 22.1 24.2 24.7 22.1 19.3 18.1 HDAC6 "FLJ16239, HD6, JM21, KIAA0901, PPP1R90" ENSG00000094631 "Histone deacetylase 6" Q9UBN7 X 48801377-48824982 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" "Actin-binding, Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003714, CAB004236, HPA026321" Supported Supported Nucleoplasm 39000 Nucleoplasm "CAB004236: AB_627708, HPA003714: AB_1850544, HPA026321: AB_1850546" "unprognostic (9.53e-2)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (2.42e-2)" "unprognostic (2.82e-2)" "unprognostic (4.11e-3)" "unprognostic (2.17e-2)" "unprognostic (1.16e-1)" "unprognostic (7.68e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-3)" "unprognostic (2.33e-2)" "unprognostic (6.10e-2)" "unprognostic (1.47e-1)" "unprognostic (6.60e-2)" "unprognostic (2.34e-1)" "prognostic favourable (3.34e-4)" 14.6 13.7 23.4 12.8 29.8 19.0 14.4 34.2 30.1 12.7 14.1 24.4 14.9 16.9 16.0 14.7 13.1 15.7 11.7 11.9 21.7 24.8 32.8 43.3 15.1 13.9 27.2 22.4 18.7 15.5 26.7 24.4 15.1 27.0 12.3 15.9 15.1 12.2 15.3 18.2 11.3 16.1 15.0 20.9 15.3 14.2 24.7 22.4 19.0 15.7 9.5 14.0 11.7 12.1 5.7 9.7 6.3 12.4 4.0 5.8 5.0 16.0 13.6 26.7 10.2 10.8 9.8 18.1 7.7 6.5 14.8 14.6 13.1 13.7 15.4 7.4 8.7 11.5 16.2 8.2 12.8 14.4 10.2 21.1 16.2 13.4 10.2 9.7 32.7 14.2 13.3 11.6 14.0 12.3 23.1 17.1 9.3 5.6 13.8 15.3 9.9 13.0 11.9 28.8 15.9 8.5 6.9 13.8 13.6 15.4 4.6 9.2 19.3 9.1 10.0 11.5 14.9 15.8 7.3 15.8 15.6 11.2 11.7 12.5 11.4 0.0 5.8 6.3 5.8 9.7 4.1 4.3 4.0 4.2 8.6 5.7 3.9 3.7 2.9 4.0 12.4 9.7 4.4 5.0 23.4 29.8 34.2 30.1 21.7 24.8 27.2 22.4 27.0 22.4 HDAC7 "DKFZP586J0917, HDAC7A" ENSG00000061273 "Histone deacetylase 7" Q8WUI4 12 47782722-47833132 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 85.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 10.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004775 Supported Cytosol Cytosol "HPA004775: AB_1850548" "unprognostic (3.83e-1)" "unprognostic (9.49e-3)" "unprognostic (1.37e-2)" "unprognostic (4.46e-2)" "unprognostic (6.56e-3)" "unprognostic (2.22e-2)" "unprognostic (2.50e-3)" "unprognostic (1.26e-1)" "prognostic unfavourable (5.16e-4)" "unprognostic (1.28e-1)" "unprognostic (2.07e-1)" "unprognostic (2.38e-2)" "prognostic unfavourable (8.25e-4)" "unprognostic (6.24e-2)" "unprognostic (4.38e-2)" "unprognostic (9.69e-2)" "prognostic favourable (4.65e-4)" 26.0 21.6 8.2 22.7 10.8 17.3 24.4 8.4 10.7 28.2 20.7 8.7 15.4 8.0 27.9 21.5 19.2 25.2 22.1 16.5 10.3 4.3 17.7 5.1 27.6 21.1 8.2 8.0 25.4 8.9 23.7 11.5 17.5 10.0 20.1 4.1 17.6 16.3 18.9 12.5 19.7 13.9 24.9 10.3 23.1 14.9 9.5 11.5 85.8 20.9 12.9 21.0 24.8 25.0 1.4 0.6 10.5 1.9 1.7 1.5 1.8 14.0 9.6 10.0 16.3 7.8 21.9 9.0 13.9 10.8 10.1 6.6 12.8 13.4 28.3 46.2 12.6 13.1 2.3 10.8 3.7 13.2 4.8 9.6 9.4 2.9 8.5 3.0 0.4 14.3 3.8 10.0 5.4 20.8 10.2 11.6 6.4 6.1 27.8 7.5 14.0 10.7 21.4 5.3 10.2 4.3 9.2 2.8 6.8 10.6 4.9 5.0 4.6 4.1 23.5 20.7 22.5 16.8 9.8 26.2 19.0 22.5 8.5 14.3 6.7 0.0 1.9 0.0 1.5 0.8 1.5 1.4 1.3 1.1 0.6 1.1 1.5 1.0 10.5 1.7 0.7 0.5 0.6 1.8 8.2 10.8 8.4 10.7 10.3 4.3 8.2 8.0 10.0 11.5 HDAC8 "HDACL1, MRXS6, RPD3, WTS" ENSG00000147099 "Histone deacetylase 8" Q9BY41 X 72329516-72573103 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Disease mutation, FDA approved drug targets, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048560 Supported Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA048560: " "unprognostic (1.42e-1)" "unprognostic (6.62e-3)" "unprognostic (3.20e-2)" "unprognostic (9.24e-3)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (4.64e-2)" "unprognostic (6.03e-2)" "unprognostic (1.58e-1)" "unprognostic (2.81e-2)" "unprognostic (3.17e-2)" "unprognostic (9.68e-2)" "unprognostic (8.42e-2)" "unprognostic (2.33e-3)" "unprognostic (9.10e-2)" "unprognostic (7.15e-3)" "unprognostic (2.12e-3)" 9.6 22.5 14.7 9.9 16.2 10.2 12.4 31.4 20.6 12.6 10.4 13.9 11.5 8.6 12.3 28.2 11.0 9.4 9.4 12.6 15.0 15.2 16.8 18.6 10.2 9.6 14.9 9.4 12.8 15.9 13.6 22.0 11.2 19.3 13.3 12.8 14.3 12.2 10.3 10.4 9.3 8.4 13.1 12.2 9.5 10.7 3.6 14.0 8.0 15.0 8.2 11.9 10.4 10.1 9.4 12.8 19.7 13.2 7.7 11.4 7.7 12.3 16.9 12.4 17.2 17.0 12.7 8.6 7.1 13.9 11.0 12.5 12.2 12.7 8.6 22.7 9.8 9.0 23.1 13.9 14.7 14.1 16.4 11.3 21.7 14.2 9.3 18.8 20.1 13.3 10.3 13.5 10.1 16.9 12.6 24.1 14.7 15.5 8.8 24.7 17.2 24.4 12.1 16.0 15.4 19.2 13.0 8.9 19.4 16.9 13.5 17.3 6.8 16.1 12.7 9.1 13.1 13.0 8.0 9.2 14.7 10.9 12.3 20.8 11.7 7.2 13.2 19.7 8.8 11.8 6.9 9.4 9.5 7.3 12.8 9.1 7.6 7.1 0.7 7.7 10.5 4.8 11.4 7.7 14.7 16.2 31.4 20.6 15.0 15.2 14.9 9.4 19.3 14.0 HDAC9 "HD7, HDAC, HDAC7B, KIAA0744, MITR" ENSG00000048052 "Histone deacetylase 9" Q9UKV0 7 18086949-19002416 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 54.3;hTERT-HME1: 26.0;SH-SY5Y: 21.7;U-698: 21.5;WM-115: 22.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 29.5" "Group enriched" "Detected in many" 9 "B-cells: 21.8;dendritic cells: 29.5;monocytes: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028926 Uncertain Approved Nucleoplasm Nucleoplasm "HPA028926: AB_10602327" "unprognostic (2.06e-2)" "unprognostic (2.67e-1)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.74e-1)" "unprognostic (5.54e-2)" "unprognostic (2.20e-2)" "unprognostic (2.32e-1)" "unprognostic (2.21e-1)" "unprognostic (2.45e-1)" "unprognostic (5.01e-1)" "unprognostic (7.58e-2)" "unprognostic (1.29e-1)" "unprognostic (3.94e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" 10.7 13.5 12.6 10.7 16.2 5.9 8.4 19.1 16.9 11.6 7.4 11.3 7.5 3.8 17.8 6.7 4.7 10.5 7.5 14.9 13.1 12.0 3.9 3.1 5.7 18.9 13.9 14.9 3.0 2.7 3.0 17.7 6.8 11.2 12.5 6.2 9.7 6.9 16.5 15.5 3.8 8.4 14.4 17.6 17.4 9.1 8.7 18.2 2.9 5.5 5.4 19.3 7.1 9.6 21.8 29.5 0.5 9.7 2.0 2.1 4.5 12.3 0.0 2.0 0.0 0.3 2.8 0.0 0.7 7.3 3.1 5.3 0.1 4.0 5.3 13.7 8.2 1.8 54.3 1.0 8.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 1.0 1.0 9.6 26.0 0.1 0.0 8.3 4.2 0.0 0.5 1.0 6.6 1.2 1.5 0.8 3.1 1.7 3.3 3.9 21.7 0.1 0.1 3.9 0.2 4.9 0.5 11.3 3.6 0.6 7.0 9.6 4.1 21.5 2.9 0.5 22.2 0.1 9.7 0.0 1.7 6.7 1.7 21.8 0.6 0.8 29.5 16.3 0.0 0.9 0.5 2.0 3.8 6.4 2.1 4.5 12.6 16.2 19.1 16.9 13.1 12.0 13.9 14.9 11.2 18.2 HDC ENSG00000140287 "Histidine decarboxylase" P19113 15 50241947-50266026 "Enzymes, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "blood: 83.5;brain: 36.0;epididymis: 36.9" "Group enriched" "Detected in some" 4 "HEL: 59.8;HMC-1: 143.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 52 "hypothalamus: 36.0" "Cell type enriched" "Detected in single" 835 "basophil: 83.5" "Lineage enriched" "Detected in single" 835 "granulocytes: 83.5" "Region enriched" "Detected in many" 5 "hypothalamus: 51.5" "Low region specificity" "Detected in all" HPA038891 Enhanced Approved "Nuclear bodies" "Nuclear bodies" "HPA038891: AB_10673231" "unprognostic (4.97e-2)" "unprognostic (7.42e-2)" "unprognostic (1.43e-4)" "unprognostic (1.08e-1)" "unprognostic (6.16e-2)" "unprognostic (3.93e-7)" "unprognostic (4.18e-5)" "unprognostic (8.79e-3)" "unprognostic (1.48e-1)" "unprognostic (8.46e-2)" "unprognostic (4.60e-2)" "unprognostic (1.05e-1)" "unprognostic (2.53e-1)" "unprognostic (7.20e-2)" "unprognostic (9.78e-2)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" 1.7 0.2 0.2 5.1 0.4 2.4 1.1 0.2 0.3 2.7 1.9 0.2 1.2 2.1 3.1 36.9 2.7 0.6 6.6 2.1 0.2 36.0 0.6 0.8 4.9 2.3 0.6 0.1 0.4 0.5 0.3 0.7 0.2 0.3 2.2 1.9 3.0 0.9 1.3 1.8 1.8 2.4 5.4 0.2 0.4 6.9 2.4 0.2 0.4 0.3 0.4 1.7 1.8 2.7 0.0 0.0 83.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 59.8 0.0 0.0 0.0 0.1 143.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.2 0.3 0.2 36.0 0.6 0.1 0.3 0.2 HDDC3 MGC45386 ENSG00000184508 "HD domain containing 3" Q8N4P3 15 90929964-90935196 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040895 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA040895: AB_10795494" "unprognostic (1.03e-1)" "unprognostic (3.78e-2)" "unprognostic (1.32e-1)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (3.75e-2)" "unprognostic (2.53e-1)" "unprognostic (3.57e-1)" "unprognostic (1.28e-1)" "unprognostic (5.93e-3)" "unprognostic (1.08e-1)" "unprognostic (1.91e-2)" "unprognostic (3.43e-2)" "unprognostic (2.26e-1)" "unprognostic (4.86e-2)" "unprognostic (3.15e-1)" "unprognostic (4.65e-1)" 14.3 18.8 16.3 8.9 17.1 10.7 11.3 10.3 17.6 8.2 13.1 9.3 12.6 12.4 5.4 12.8 7.7 12.7 7.1 15.2 12.9 12.3 14.7 18.3 7.8 9.0 14.6 12.5 10.3 30.3 15.1 10.4 10.4 11.0 8.7 11.1 9.7 24.8 14.0 14.2 9.3 17.1 6.1 11.4 13.1 11.2 4.5 8.2 11.8 12.0 10.1 10.7 7.5 7.5 19.9 25.3 5.6 15.6 16.4 21.5 14.3 6.9 8.5 3.0 3.6 6.9 7.0 5.0 4.6 6.4 4.4 6.5 4.3 14.4 13.0 4.9 3.9 10.8 6.3 10.9 3.7 16.5 13.2 16.5 3.3 9.6 14.1 6.2 8.1 6.1 17.2 8.0 14.4 9.6 13.1 11.8 3.9 10.1 8.5 5.4 2.4 8.8 7.2 1.1 20.8 9.0 7.3 7.6 4.9 3.9 11.0 11.7 16.6 17.0 5.5 2.7 6.1 4.6 6.0 19.4 21.7 9.0 10.1 12.3 8.1 5.6 11.8 4.7 14.0 15.6 18.4 19.9 18.4 16.2 15.9 17.5 21.5 15.7 2.8 16.4 14.2 25.3 17.4 14.3 16.3 17.1 10.3 17.6 12.9 12.3 14.6 12.5 11.0 8.2 HECTD1 KIAA1131 ENSG00000092148 "HECT domain E3 ubiquitin protein ligase 1" Q9ULT8 14 31100112-31207804 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002929, HPA054461" Approved Enhanced Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA002929: AB_1850574, HPA054461: " "unprognostic (6.71e-2)" "unprognostic (4.86e-2)" "unprognostic (5.31e-2)" "unprognostic (1.25e-1)" "unprognostic (1.64e-1)" "unprognostic (6.99e-2)" "unprognostic (1.32e-1)" "unprognostic (7.03e-2)" "unprognostic (2.29e-2)" "unprognostic (3.13e-2)" "unprognostic (3.60e-3)" "unprognostic (1.51e-1)" "prognostic favourable (1.20e-6)" "unprognostic (6.53e-2)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (9.91e-3)" 22.0 22.3 14.2 21.0 16.8 22.0 18.5 22.3 18.9 19.4 17.9 15.2 20.2 11.5 17.6 15.7 30.4 16.1 15.2 26.2 13.5 14.3 18.0 35.2 15.0 14.1 14.5 14.5 18.2 15.1 34.8 20.5 27.0 18.8 16.8 15.5 16.8 18.9 16.4 88.5 24.3 16.3 15.6 13.7 16.4 18.8 18.9 14.4 16.7 24.8 23.0 18.6 18.6 22.3 10.6 9.3 12.6 8.6 8.9 8.1 3.3 28.4 17.8 15.7 9.8 49.6 26.0 15.0 17.4 17.6 15.6 13.5 13.3 15.4 22.3 18.5 31.8 19.3 20.8 15.7 23.7 13.6 8.5 22.8 14.7 53.1 23.1 23.7 16.8 22.8 21.8 17.5 27.5 28.6 16.4 10.4 24.2 23.3 9.2 10.1 11.9 16.2 17.0 18.1 9.7 24.3 29.5 11.6 13.6 25.5 17.7 15.4 18.6 15.3 28.6 18.1 14.2 13.0 14.7 11.4 16.1 25.2 8.6 12.0 15.2 12.6 8.6 11.3 7.1 7.1 8.1 7.2 8.0 6.3 9.3 10.6 6.7 6.6 4.4 8.9 5.3 7.8 8.0 3.3 14.2 16.8 22.3 18.9 13.5 14.3 14.5 14.5 18.8 14.4 HECTD2 FLJ37306 ENSG00000165338 "HECT domain E3 ubiquitin protein ligase 2" Q5U5R9 10 91409280-91514829 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 21.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 7 "NK-cell: 6.7" "Lineage enriched" "Detected in many" 7 "NK-cells: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037767 Approved Approved Nucleoplasm Nucleoplasm "HPA037767: AB_10671378" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.26e-2)" "unprognostic (3.34e-1)" "unprognostic (6.65e-3)" "unprognostic (1.10e-2)" "unprognostic (9.37e-4)" "unprognostic (1.42e-1)" "unprognostic (1.59e-1)" "unprognostic (2.31e-1)" "unprognostic (2.54e-3)" "unprognostic (4.44e-2)" "prognostic unfavourable (1.67e-5)" "unprognostic (6.98e-3)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (5.84e-2)" 8.7 8.8 16.5 6.9 17.9 2.4 10.8 20.3 19.5 14.3 10.1 5.1 9.1 4.6 17.2 16.6 8.3 12.1 11.4 8.1 11.9 8.7 7.3 4.7 8.7 4.7 5.8 11.3 16.8 7.4 14.4 18.6 10.2 6.5 24.8 7.6 7.5 7.7 24.3 7.7 6.8 6.0 18.4 6.8 5.3 7.5 9.7 6.4 2.9 9.8 5.1 3.6 13.7 10.5 0.6 0.4 0.1 0.8 6.7 1.0 0.5 4.0 2.1 21.2 8.7 4.7 5.1 3.8 3.3 4.5 6.8 6.3 0.2 3.9 0.0 2.9 3.4 0.3 5.7 2.4 8.4 4.4 7.1 2.3 14.9 1.3 2.3 0.4 1.5 5.2 2.2 4.9 4.2 5.1 3.1 10.6 10.5 1.9 2.5 1.3 8.8 2.1 6.3 14.0 2.4 4.7 1.1 5.0 5.3 6.5 1.5 6.6 9.6 1.4 5.3 6.9 4.7 0.4 6.3 0.7 1.4 5.9 6.0 0.0 3.9 0.0 0.1 0.0 1.0 0.8 0.6 0.2 0.5 0.7 0.4 0.6 0.5 0.6 0.1 6.7 0.2 0.0 0.1 0.5 16.5 17.9 20.3 19.5 11.9 8.7 5.8 11.3 6.5 6.4 HECTD3 FLJ21156 ENSG00000126107 "HECT domain E3 ubiquitin protein ligase 3" Q5T447 1 45002540-45011329 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027467 Approved 34000 "HPA027467: AB_10600710" "unprognostic (1.86e-1)" "unprognostic (1.19e-2)" "unprognostic (2.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.18e-1)" "unprognostic (2.05e-1)" "prognostic unfavourable (2.14e-5)" "unprognostic (1.74e-2)" "unprognostic (2.92e-2)" "unprognostic (7.42e-2)" "unprognostic (2.47e-1)" "unprognostic (8.39e-2)" "unprognostic (2.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.35e-1)" "prognostic favourable (1.85e-6)" "unprognostic (3.19e-1)" 18.4 16.9 9.6 16.7 11.1 9.2 25.9 12.4 14.8 11.2 38.0 14.8 11.7 34.1 12.4 12.4 16.7 9.1 14.6 8.7 9.9 8.4 16.4 22.9 10.5 11.3 10.9 7.9 14.1 24.1 22.9 8.0 11.8 10.8 10.4 19.5 9.7 27.0 15.4 24.2 20.1 59.3 12.0 9.9 14.0 13.9 11.7 9.7 11.9 13.3 14.8 12.5 13.8 12.0 8.7 9.9 10.4 15.1 5.0 10.9 7.5 11.2 10.2 6.5 10.6 23.1 14.5 13.0 10.8 16.4 11.9 13.5 14.5 3.5 5.3 9.2 17.6 10.5 15.5 11.2 10.7 9.8 12.0 8.5 14.9 12.7 20.2 6.6 14.3 15.6 19.2 20.3 7.9 26.5 18.9 6.0 15.1 9.6 8.3 5.4 9.0 15.6 9.9 11.8 7.6 17.5 13.3 15.8 6.6 14.5 25.2 12.8 8.2 6.2 19.8 13.8 11.0 17.1 12.2 7.7 9.0 2.9 22.1 7.2 6.7 9.4 10.4 10.4 10.9 15.1 9.1 8.7 8.9 9.3 9.9 5.1 7.5 8.9 4.0 5.0 8.2 7.5 9.0 7.5 9.6 11.1 12.4 14.8 9.9 8.4 10.9 7.9 10.8 9.7 HECW1 "KIAA0322, NEDL1" ENSG00000002746 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1" Q76N89 7 43112599-43566001 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;kidney: 15.4" "Cell line enhanced" "Detected in some" "A549: 5.5;U-266/70: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007203, HPA007593, HPA007609" Approved Supported Cytosol Cytosol "HPA007203: , HPA007593: AB_1852305, HPA007609: AB_2117518" "unprognostic (1.40e-1)" "unprognostic (2.85e-3)" "unprognostic (2.57e-1)" "unprognostic (4.39e-1)" "unprognostic (2.43e-2)" "unprognostic (2.80e-2)" "unprognostic (8.65e-4)" "unprognostic (6.93e-2)" "unprognostic (7.30e-2)" "unprognostic (7.31e-2)" "unprognostic (3.43e-2)" "unprognostic (2.67e-2)" "unprognostic (1.43e-3)" "unprognostic (1.64e-2)" "unprognostic (5.23e-3)" "unprognostic (1.89e-2)" "unprognostic (2.42e-2)" 0.7 0.5 10.3 0.8 12.1 1.4 0.8 13.6 24.0 0.6 0.8 1.1 0.0 0.4 0.8 1.7 2.6 0.5 4.0 0.4 3.9 4.1 15.4 0.6 0.6 1.3 3.8 15.5 1.0 0.4 1.7 0.4 0.6 10.2 3.2 0.5 0.6 1.0 0.8 1.8 2.1 0.6 0.7 1.4 0.6 1.0 3.7 1.6 0.0 1.5 0.0 0.8 1.2 0.6 2.4 1.6 7.0 1.7 1.6 0.7 0.1 0.1 5.5 0.6 0.8 0.0 0.0 0.0 1.6 2.8 0.1 0.6 0.0 0.0 0.2 3.0 2.7 0.4 0.0 0.0 0.2 0.2 0.9 0.0 0.4 0.2 0.2 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 2.3 0.9 0.5 0.0 0.0 0.0 0.1 0.2 0.7 0.5 0.1 0.0 0.4 0.0 0.0 0.8 1.1 1.3 0.4 15.6 0.5 0.0 3.5 0.4 0.0 6.4 1.7 1.1 0.7 1.0 0.5 1.0 0.7 0.3 0.2 2.4 0.6 0.7 7.0 1.6 0.9 1.6 0.2 0.1 10.3 12.1 13.6 24.0 3.9 4.1 3.8 15.5 10.2 1.6 HECW2 "KIAA1301, NEDL2" ENSG00000138411 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2" Q9P2P5 2 196189099-196593692 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 26.6;HUVEC TERT2: 15.0;SCLC-21H: 17.4;TIME: 19.7;U-138 MG: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 7.7;non-classical monocyte: 5.2" "Group enriched" "Detected in many" 9 "granulocytes: 7.7;monocytes: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034609 Enhanced "HPA034609: AB_10669993" "unprognostic (2.65e-2)" "unprognostic (3.89e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-3)" "unprognostic (2.55e-1)" "unprognostic (4.28e-2)" "unprognostic (7.63e-3)" "unprognostic (1.23e-1)" "unprognostic (2.61e-2)" "unprognostic (7.05e-2)" "unprognostic (4.16e-2)" "unprognostic (2.27e-1)" "prognostic unfavourable (5.18e-5)" "unprognostic (8.05e-3)" "unprognostic (5.20e-2)" "unprognostic (1.49e-1)" "unprognostic (4.48e-2)" 8.8 3.3 6.7 2.6 12.6 0.6 4.2 15.7 17.2 4.6 1.2 11.6 0.0 1.1 3.0 1.0 5.5 6.3 4.8 14.0 6.7 4.3 3.4 5.6 16.4 3.5 8.2 9.3 1.3 2.1 14.7 5.9 15.5 9.5 1.5 1.3 1.2 2.2 1.3 2.7 2.7 1.7 3.1 5.8 11.6 2.1 5.8 8.8 0.0 7.9 1.6 4.2 2.4 2.5 0.6 0.7 7.7 5.2 0.0 0.1 0.1 0.0 0.7 1.2 0.0 0.7 2.3 0.9 1.5 3.9 1.2 1.4 0.1 0.0 0.7 0.3 7.2 1.7 0.5 0.1 2.5 26.6 0.9 0.0 1.1 0.1 0.1 0.2 0.2 0.5 0.7 8.9 3.1 15.0 0.1 0.0 3.6 0.9 0.0 0.3 1.4 0.6 0.0 0.3 0.0 0.0 0.0 17.4 1.4 1.1 0.2 0.0 0.0 0.1 19.7 12.0 0.8 2.6 0.3 0.1 0.0 0.7 3.0 0.0 0.1 0.2 0.5 1.3 0.0 1.9 0.0 0.5 0.1 0.0 0.7 0.6 0.1 0.0 7.7 0.0 5.2 0.0 0.1 0.1 6.7 12.6 15.7 17.2 6.7 4.3 8.2 9.3 9.5 8.8 HELQ Hel308 ENSG00000163312 "Helicase, POLQ like" Q8TDG4 4 83407343-83455856 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036852, HPA036853" Approved Approved "Nucleoplasm,Nuclear speckles" "Nuclear speckles" Nucleoplasm "HPA036852: , HPA036853: AB_10672102" "unprognostic (4.58e-2)" "unprognostic (3.25e-2)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" "unprognostic (4.80e-2)" "unprognostic (5.56e-2)" "unprognostic (1.14e-1)" "unprognostic (5.13e-3)" "unprognostic (7.14e-2)" "unprognostic (8.62e-2)" "prognostic favourable (9.07e-4)" "unprognostic (2.03e-1)" "prognostic favourable (2.76e-4)" "unprognostic (3.54e-2)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.37e-1)" 10.5 20.8 6.3 12.2 7.8 7.2 10.4 12.6 9.2 10.7 9.8 9.3 8.2 5.6 9.9 8.7 8.2 9.1 9.0 10.5 6.2 5.7 11.9 10.0 8.0 15.3 6.8 5.7 17.4 8.1 13.3 20.7 11.7 9.0 11.4 7.2 11.0 10.0 10.4 14.6 8.7 9.8 8.0 8.4 14.4 8.4 10.7 7.4 18.5 14.3 8.3 13.4 10.2 9.2 10.1 4.6 6.8 4.7 5.5 9.7 2.9 4.2 3.2 7.0 4.5 8.5 9.0 3.6 6.3 9.5 8.3 8.2 3.1 4.4 11.9 5.1 5.5 4.3 8.4 4.7 8.7 6.9 3.7 7.1 5.3 4.1 5.5 8.6 17.6 7.0 6.3 6.6 6.8 6.6 9.3 10.5 8.4 5.0 7.8 6.2 3.6 2.4 6.1 8.0 4.2 6.8 2.7 5.7 4.7 6.2 6.8 6.9 4.2 9.3 5.0 6.2 5.5 8.0 4.9 9.6 4.1 10.1 5.2 6.5 6.9 5.4 3.7 6.8 5.7 4.0 5.4 5.8 6.3 6.4 4.6 10.1 9.7 8.7 2.3 5.5 4.7 4.5 7.8 2.9 6.3 7.8 12.6 9.2 6.2 5.7 6.8 5.7 9.0 7.4 HENMT1 "C1orf59, FLJ30525, HEN1" ENSG00000162639 "HEN methyltransferase 1" Q5T8I9 1 108648290-108661526 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 28.8;testis: 45.2" "Cell line enhanced" "Detected in many" "MOLT-4: 23.9;NB-4: 26.7;THP-1: 20.0;U-937: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 16 "cerebellum: 18.1" "HPA028464, HPA028497" Uncertain Approved "Plasma membrane,Focal adhesion sites" "Plasma membrane, Focal adhesion sites" "HPA028464: AB_10600103, HPA028497: AB_10601552" "unprognostic (1.82e-1)" "prognostic favourable (2.56e-4)" "prognostic favourable (9.95e-4)" "unprognostic (2.92e-3)" "unprognostic (1.91e-1)" "unprognostic (3.88e-3)" "unprognostic (2.01e-2)" "unprognostic (1.49e-1)" "unprognostic (7.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.95e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (2.48e-5)" "unprognostic (2.53e-1)" "unprognostic (2.43e-1)" "unprognostic (2.18e-1)" "unprognostic (1.65e-1)" 3.5 2.2 6.7 5.1 10.2 7.7 5.5 3.6 11.6 6.1 4.4 4.2 1.4 3.4 2.8 3.4 1.9 1.8 4.5 3.1 9.5 10.1 1.8 1.4 4.9 9.8 8.2 5.6 3.8 1.5 0.6 3.9 3.8 10.7 2.7 6.6 1.3 2.4 2.6 2.0 2.6 5.2 2.5 6.9 8.0 3.2 45.2 2.5 10.3 1.7 1.2 7.3 5.5 1.6 5.4 10.6 18.2 12.0 22.9 28.8 15.9 5.9 3.0 0.2 0.0 0.2 0.2 0.0 1.4 0.5 3.5 0.5 8.9 9.4 0.0 3.3 2.7 0.0 0.0 0.0 2.2 1.9 0.0 15.1 11.5 0.0 3.1 8.9 13.5 2.9 0.1 0.7 0.0 0.7 0.0 6.8 0.1 15.1 23.9 26.7 8.8 1.3 10.4 0.0 0.5 0.0 6.5 14.9 0.0 12.8 3.6 0.0 0.0 20.0 0.1 0.0 11.8 6.4 0.0 4.1 5.2 0.0 0.0 35.2 0.1 16.0 8.8 18.2 28.8 10.1 26.0 5.4 14.2 26.0 10.6 2.9 11.8 21.7 8.6 22.9 12.0 8.5 13.1 15.9 6.7 10.2 3.6 11.6 9.5 10.1 8.2 5.6 10.7 2.5 HERC1 "p532, p619" ENSG00000103657 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 1" Q15751 15 63608618-63833942 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049749 Uncertain "HPA049749: " "unprognostic (9.72e-2)" "unprognostic (7.51e-2)" "unprognostic (3.43e-1)" "unprognostic (3.80e-1)" "unprognostic (2.35e-1)" "prognostic favourable (4.87e-5)" "unprognostic (1.53e-1)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (2.89e-3)" "prognostic favourable (3.66e-4)" "unprognostic (1.24e-1)" "prognostic favourable (1.36e-6)" "unprognostic (2.87e-1)" "unprognostic (3.36e-2)" "unprognostic (9.04e-3)" "unprognostic (3.94e-1)" 14.4 11.7 20.3 12.9 23.5 28.9 15.5 30.4 29.7 17.4 15.3 14.7 13.8 7.0 15.8 8.9 10.3 10.7 12.1 17.6 19.4 14.3 11.9 11.4 14.9 15.2 12.8 23.7 23.8 11.5 44.8 20.1 12.7 19.1 11.4 11.8 11.0 11.4 14.0 31.7 14.6 13.9 15.7 11.7 17.4 13.5 13.5 15.8 16.6 17.2 11.3 15.3 12.9 11.6 9.8 7.0 17.6 5.7 2.8 6.6 1.4 7.4 9.8 10.9 3.8 19.4 12.5 3.6 5.9 7.6 6.2 7.1 6.0 3.0 11.1 5.5 11.0 8.1 17.6 5.0 8.4 8.5 6.0 24.1 13.9 4.3 3.2 17.8 14.5 8.9 4.9 8.6 8.5 12.8 24.2 5.0 5.3 12.1 6.2 3.5 5.4 5.0 6.8 12.1 6.5 2.5 18.4 9.8 4.9 10.4 7.1 6.2 3.5 7.1 14.2 8.0 7.4 6.8 7.7 5.5 9.4 7.8 4.5 13.3 2.7 17.6 3.7 7.4 5.0 3.3 3.8 5.3 5.5 4.4 3.2 9.8 5.6 5.6 12.9 2.8 5.7 7.0 6.6 1.4 20.3 23.5 30.4 29.7 19.4 14.3 12.8 23.7 19.1 15.8 HERC2 "D15F37S1, jdf2, p528" ENSG00000128731 "HECT and RLD domain containing E3 ubiquitin protein ligase 2" O95714 15 28111040-28322152 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 32.6" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017188, HPA048389, HPA074166" Approved Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "CAB017188: , HPA048389: , HPA074166: " "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.92e-1)" "unprognostic (6.64e-2)" "unprognostic (6.62e-2)" "unprognostic (5.74e-2)" "unprognostic (9.17e-2)" "unprognostic (2.08e-1)" "unprognostic (1.87e-1)" "unprognostic (4.11e-2)" "unprognostic (9.40e-3)" "unprognostic (3.60e-2)" "prognostic favourable (1.41e-7)" "unprognostic (7.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.34e-2)" "unprognostic (1.71e-1)" 2.5 3.3 3.2 2.2 4.5 3.9 3.1 7.0 5.7 3.2 4.6 2.7 4.4 1.7 2.8 4.1 2.1 4.6 3.5 3.6 3.3 1.6 2.5 2.1 3.8 8.5 3.6 9.2 3.5 2.7 3.0 3.0 2.3 3.3 8.2 3.1 3.1 4.1 4.1 2.3 3.4 3.2 5.6 2.4 3.3 2.3 1.0 1.1 0.5 0.4 0.2 1.1 0.4 5.1 10.1 7.0 2.9 5.9 4.4 2.0 3.7 4.4 4.8 4.6 5.2 0.6 5.1 4.5 6.3 5.2 7.4 3.6 3.5 3.1 4.8 32.6 11.7 1.7 2.2 7.6 2.6 3.7 2.9 5.7 7.1 6.3 12.5 2.1 4.5 2.3 1.7 2.5 2.1 4.4 6.1 10.0 0.4 1.6 11.1 7.8 4.5 8.9 2.5 2.9 3.0 9.0 9.4 8.9 5.8 3.4 5.5 1.4 1.9 4.8 4.1 3.6 4.7 0.0 0.4 0.5 1.1 0.1 0.6 0.5 0.2 0.5 1.1 1.0 0.9 0.5 0.0 0.2 0.3 0.9 0.4 0.4 HERC3 KIAA0032 ENSG00000138641 "HECT and RLD domain containing E3 ubiquitin protein ligase 3" Q15034 4 88592423-88708542 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039170 Approved Approved Cytosol Cytosol "HPA039170: AB_10673414" "unprognostic (2.21e-2)" "unprognostic (1.65e-2)" "unprognostic (9.28e-3)" "unprognostic (3.24e-1)" "unprognostic (6.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.30e-2)" "unprognostic (1.85e-2)" "unprognostic (9.77e-2)" "unprognostic (6.51e-3)" "unprognostic (3.48e-3)" "unprognostic (2.58e-2)" "prognostic favourable (5.65e-7)" "unprognostic (1.83e-1)" "unprognostic (3.21e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-2)" 12.7 13.3 16.9 13.0 27.1 21.0 15.3 37.8 20.1 14.4 12.0 17.9 11.6 11.2 12.0 10.5 16.8 10.7 12.1 22.0 15.2 13.7 15.8 13.0 15.0 15.3 21.9 15.0 12.7 9.7 33.8 16.1 10.0 21.1 22.0 13.4 22.0 14.0 14.0 17.3 19.1 12.8 13.8 16.3 15.7 12.9 3.6 21.5 16.6 15.7 12.6 16.4 13.3 16.7 5.2 7.0 18.2 9.7 3.1 9.0 3.9 7.2 1.1 1.3 2.3 7.7 16.4 4.6 8.2 15.0 8.6 5.7 1.8 8.4 7.7 3.9 27.0 2.5 1.9 7.4 8.2 3.4 2.2 5.3 3.3 1.2 4.4 13.1 9.6 7.8 9.2 8.1 36.8 9.4 3.8 3.4 17.3 2.1 9.0 3.1 0.4 2.0 10.2 9.5 3.1 5.5 1.3 1.9 1.8 9.4 6.0 3.2 1.0 5.9 14.7 9.7 5.3 9.1 6.1 6.4 1.6 4.4 6.1 6.0 4.0 5.7 5.7 7.7 4.7 6.2 5.5 5.2 5.5 4.7 7.0 4.9 8.2 5.8 18.2 3.1 9.7 2.4 9.0 3.9 16.9 27.1 37.8 20.1 15.2 13.7 21.9 15.0 21.1 21.5 HERC4 "DKFZP564G092, KIAA1593" ENSG00000148634 "HECT and RLD domain containing E3 ubiquitin protein ligase 4" Q5GLZ8 10 67921899-68075348 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 55.1;fHDF/TERT166: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045453, HPA070301" Uncertain Supported "Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoli fibrillar center" "HPA045453: AB_10961917, HPA070301: " "unprognostic (3.66e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-1)" "unprognostic (4.23e-2)" "unprognostic (3.51e-2)" "unprognostic (1.01e-3)" "unprognostic (3.54e-1)" "unprognostic (8.57e-2)" "unprognostic (4.94e-3)" "unprognostic (2.25e-2)" "prognostic unfavourable (3.86e-5)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (3.98e-1)" "unprognostic (2.31e-2)" 25.3 29.4 21.9 28.0 28.4 14.6 22.7 30.5 24.9 24.2 20.5 22.2 26.7 20.0 28.1 24.3 22.2 19.2 20.2 20.5 21.9 22.7 20.6 24.5 20.6 30.2 30.9 14.8 24.5 17.1 25.2 35.6 23.8 26.8 19.4 23.9 17.8 17.7 24.1 19.6 20.9 25.8 23.0 28.7 27.0 17.3 22.2 33.6 23.6 19.5 13.8 28.3 24.7 47.9 7.7 10.4 13.5 9.3 9.9 11.5 6.5 22.4 8.0 5.1 8.5 13.2 18.1 4.6 55.1 34.1 20.7 13.4 4.5 10.6 7.9 4.3 61.8 11.9 5.6 8.1 28.0 5.2 2.7 3.6 13.3 3.5 7.0 4.4 6.5 8.9 9.5 11.0 9.8 12.8 3.8 4.0 31.9 9.6 3.1 5.2 3.0 14.0 4.2 2.1 2.8 9.4 6.4 2.4 2.8 17.9 7.7 7.8 4.8 5.6 17.4 10.9 6.1 26.8 9.4 2.8 3.3 5.0 20.0 8.6 3.7 13.5 9.3 11.1 8.2 7.9 11.5 7.7 9.1 9.8 10.4 7.5 8.8 9.0 11.7 9.9 7.6 2.7 10.6 6.5 21.9 28.4 30.5 24.9 21.9 22.7 30.9 14.8 26.8 33.6 HERC6 FLJ20637 ENSG00000138642 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 6" Q8IVU3 4 88378739-88443111 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "BJ hTERT+ SV40 Large T+: 46.0;BJ hTERT+ SV40 Large T+ RasG12V: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035846 Uncertain Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA035846: AB_10673487" "unprognostic (1.95e-2)" "unprognostic (2.71e-1)" "unprognostic (2.23e-2)" "unprognostic (2.67e-2)" "unprognostic (8.61e-2)" "unprognostic (2.98e-2)" "unprognostic (2.78e-2)" "unprognostic (3.27e-1)" "unprognostic (1.49e-1)" "unprognostic (5.95e-2)" "unprognostic (1.52e-2)" "unprognostic (6.22e-2)" "prognostic favourable (7.14e-5)" "unprognostic (1.80e-1)" "unprognostic (2.59e-1)" "unprognostic (8.43e-3)" "unprognostic (3.77e-2)" 8.0 7.5 7.8 7.2 10.2 7.3 6.3 2.1 14.6 13.6 6.3 5.9 3.4 5.4 13.2 9.6 23.9 10.4 11.2 9.8 7.7 8.4 10.4 5.0 8.3 4.6 7.3 15.8 9.8 6.3 5.2 8.4 7.1 8.5 9.1 6.5 7.2 28.4 5.7 2.9 4.3 7.1 8.5 5.6 8.0 7.3 3.9 5.3 9.0 5.9 7.6 7.8 7.2 13.8 3.6 2.7 4.5 6.4 5.6 13.4 4.2 2.5 1.7 0.1 0.3 0.1 1.5 0.5 0.3 8.6 46.0 34.3 0.1 3.2 0.0 0.6 0.8 0.9 4.2 2.2 3.0 5.2 0.8 2.4 1.4 0.2 1.5 4.2 1.6 2.1 0.5 3.5 0.1 1.3 0.0 0.5 1.0 1.5 1.9 1.3 0.6 0.8 1.3 0.0 0.1 3.1 3.1 0.1 1.1 3.2 1.0 5.1 1.9 0.7 0.4 0.6 0.8 0.1 0.8 0.1 0.0 0.0 2.1 0.9 2.1 4.4 3.1 4.5 6.7 3.1 13.4 3.6 9.4 6.5 2.7 2.7 7.5 5.1 1.9 5.6 6.4 0.3 11.8 4.2 7.8 10.2 2.1 14.6 7.7 8.4 7.3 15.8 8.5 5.3 HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340919-72376476 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA054583 Supported "Intracellular and membrane" 20000000 "HPA054583: AB_2682531" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (3.41e-1)" "prognostic favourable (5.63e-8)" "unprognostic (6.58e-2)" "unprognostic (1.32e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (3.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (9.98e-2)" "unprognostic (3.98e-1)" "unprognostic (7.05e-3)" "unprognostic (3.02e-2)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" 30.1 37.4 23.1 18.0 22.9 35.5 37.8 23.3 28.1 30.6 20.5 19.4 30.1 18.5 25.9 65.7 11.7 21.8 29.2 33.8 23.4 12.8 34.6 29.5 43.9 31.4 24.9 21.1 20.9 22.2 18.1 22.9 37.9 18.8 18.1 26.0 26.9 24.8 22.0 17.7 17.9 24.6 23.4 21.4 31.5 22.6 18.0 22.9 12.1 31.2 11.1 16.4 26.7 17.1 16.1 37.9 22.4 32.7 17.8 18.1 21.3 7.4 12.7 5.5 10.5 45.0 51.4 7.8 10.5 53.3 22.8 36.5 6.7 54.8 6.2 10.1 21.0 15.0 14.4 6.7 14.5 5.0 5.8 7.8 12.6 11.5 34.9 18.7 22.4 43.7 20.0 9.9 17.8 20.8 12.1 38.8 30.3 6.4 4.0 9.4 3.1 0.1 4.2 11.9 14.0 25.5 11.8 4.7 5.2 26.3 24.8 59.3 4.6 23.6 10.4 34.2 14.3 31.4 11.1 20.7 27.9 6.5 12.4 25.0 16.5 8.9 32.7 22.4 18.1 13.7 15.8 16.1 12.0 15.8 37.9 15.6 9.5 14.0 3.1 17.8 4.8 14.4 10.7 21.3 23.1 22.9 23.3 28.1 23.4 12.8 24.9 21.1 18.8 22.9 HEXB ENSG00000049860 "Hexosaminidase subunit beta" P07686 5 74640023-74722647 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 174.3" "Cell line enhanced" "Detected in many" "ASC diff: 112.8;BJ hTERT+: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055409, HPA056010" Enhanced "Intracellular and membrane" 43000000 "HPA055409: AB_2682808, HPA056010: AB_2683008" "unprognostic (3.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.85e-2)" "unprognostic (8.72e-2)" "unprognostic (1.12e-2)" "unprognostic (6.44e-3)" "prognostic unfavourable (3.36e-8)" "unprognostic (2.21e-1)" "unprognostic (5.01e-2)" "unprognostic (1.58e-3)" "unprognostic (6.45e-2)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (1.31e-2)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" 48.0 21.9 7.7 13.6 11.6 11.1 26.1 7.4 11.2 25.8 34.2 9.5 18.0 21.6 22.1 77.3 20.6 17.3 28.1 46.3 7.1 9.1 30.4 44.5 40.9 19.3 8.5 6.7 22.7 30.4 21.8 14.3 174.3 9.3 22.6 26.3 21.0 34.6 13.3 21.0 15.3 33.6 21.0 8.7 20.5 20.7 16.2 6.1 10.8 33.7 15.2 15.4 24.0 19.7 8.9 59.8 23.8 65.9 7.6 16.4 42.9 21.1 16.7 5.8 19.2 112.8 34.8 19.0 26.0 84.4 25.4 55.2 19.5 27.7 0.0 20.7 21.3 17.0 6.2 26.5 33.6 11.8 11.2 2.8 16.2 14.7 33.1 2.3 22.9 30.7 15.6 26.7 17.9 29.1 7.8 34.7 27.8 21.5 2.7 5.3 5.4 7.5 6.4 8.5 27.6 17.5 19.4 3.8 4.7 20.2 13.7 25.1 14.5 15.7 17.2 16.8 4.2 30.8 24.0 16.1 27.6 0.1 38.2 20.8 30.4 14.5 65.9 18.6 14.2 24.5 16.4 8.9 11.7 13.1 59.8 5.5 11.2 10.9 23.8 7.6 14.6 18.0 13.7 42.9 7.7 11.6 7.4 11.2 7.1 9.1 8.5 6.7 9.3 6.1 HEXDC FLJ23825 ENSG00000169660 "Hexosaminidase D" Q8WVB3 17 82418318-82442645 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 72.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 30.3" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022834, HPA023379, HPA027844" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" "Nucleoli fibrillar center, Mitochondria" "HPA022834: AB_1850641, HPA023379: AB_1850643, HPA027844: AB_10600711" "unprognostic (8.69e-3)" "prognostic favourable (7.70e-4)" "unprognostic (7.92e-2)" "unprognostic (1.53e-1)" "unprognostic (3.51e-2)" "prognostic favourable (2.71e-4)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (2.71e-1)" "unprognostic (1.14e-2)" "prognostic favourable (5.57e-4)" "unprognostic (9.04e-3)" "unprognostic (1.83e-1)" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (1.24e-1)" "prognostic favourable (2.52e-5)" 12.7 8.5 7.1 16.6 9.3 14.3 8.7 13.2 7.3 10.1 7.6 8.8 12.8 8.0 10.0 11.1 7.9 10.3 9.4 5.7 7.2 4.6 9.9 11.6 12.4 11.6 12.8 5.5 13.6 72.9 10.2 14.6 5.7 7.4 14.1 4.2 7.0 13.3 9.2 20.4 11.3 12.3 6.0 6.1 15.6 8.8 4.7 11.4 8.6 11.7 8.6 10.7 8.3 8.8 5.9 30.3 3.3 11.5 11.9 9.8 4.4 3.0 7.6 3.4 5.2 10.2 8.9 10.4 3.8 4.7 4.1 4.6 2.6 10.3 7.9 4.2 1.6 4.2 2.0 2.3 1.9 5.5 12.9 3.6 6.7 4.5 9.2 2.4 9.2 6.3 2.3 1.1 4.1 5.2 4.5 2.7 1.1 6.9 8.3 8.9 3.1 4.6 9.8 2.8 15.5 3.1 4.5 4.7 10.1 8.0 5.2 7.2 8.4 9.1 5.2 2.6 5.0 2.0 2.6 12.5 2.3 5.9 2.1 6.8 2.7 3.3 1.7 2.7 9.8 11.5 6.5 4.6 2.2 3.4 2.0 5.9 3.5 5.1 3.0 11.9 4.9 30.3 1.4 4.4 7.1 9.3 13.2 7.3 7.2 4.6 12.8 5.5 7.4 11.4 HFM1 "FLJ36760, FLJ39011, MER3, SEC63D1" ENSG00000162669 "HFM1, ATP dependent DNA helicase homolog" A2PYH4 1 91260766-91404869 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Meiosis "Helicase, Hydrolase" "Disease mutation, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;testis: 19.9" "Cell line enhanced" "Detected in some" "AF22: 9.1;AN3-CA: 4.8;K-562: 4.9;SCLC-21H: 3.1;SH-SY5Y: 3.8;U-266/70: 4.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035036, HPA035557" Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA035036: , HPA035557: AB_10696507" "unprognostic (1.35e-2)" "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.83e-4)" "unprognostic (2.05e-2)" "unprognostic (1.52e-1)" "unprognostic (7.43e-3)" "unprognostic (1.79e-1)" "unprognostic (7.75e-2)" "unprognostic (7.97e-2)" "unprognostic (1.76e-4)" "unprognostic (2.81e-2)" "unprognostic (1.06e-2)" "unprognostic (2.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.77e-4)" "unprognostic (9.59e-2)" 0.8 0.7 2.6 0.3 4.1 0.4 0.8 11.3 4.4 1.7 0.9 1.5 2.7 0.6 3.7 2.5 0.4 1.2 0.6 1.0 2.3 0.9 1.3 0.4 0.5 1.6 0.7 1.4 6.4 1.2 0.1 7.8 0.9 3.9 1.1 0.7 2.7 1.0 2.0 2.3 0.4 0.5 1.7 4.7 0.7 0.6 19.9 1.5 0.0 2.7 0.5 0.4 0.7 2.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 9.1 4.8 0.0 0.2 0.1 0.5 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 1.0 0.0 0.1 0.2 1.1 0.0 0.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.6 0.2 2.4 0.0 0.3 1.4 0.1 0.0 0.0 3.1 3.8 0.0 0.0 1.2 0.0 0.8 0.1 0.0 1.0 0.9 0.1 4.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.6 4.1 11.3 4.4 2.3 0.9 0.7 1.4 3.9 1.5 HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628173-120682571 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 176.7" "Cell line enhanced" "Detected in some" "CACO-2: 13.1;EFO-21: 23.3;Hep G2: 44.9;RPTEC TERT1: 58.4" "Cancer enhanced" "Detected in many" "liver cancer: 119.8" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "neutrophil: 2.8" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" 210000 "Golgi apparatus" "HPA047374: AB_2680019, HPA052359: AB_2681798" "unprognostic (1.36e-1)" "unprognostic (9.89e-2)" "unprognostic (3.93e-2)" "prognostic favourable (1.78e-4)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (5.65e-3)" "unprognostic (7.20e-2)" "unprognostic (6.05e-2)" "unprognostic (2.41e-3)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (4.29e-3)" "unprognostic (8.57e-2)" "unprognostic (1.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" 0.2 0.2 0.2 0.6 0.6 0.0 1.8 0.2 0.5 3.7 7.2 0.3 1.4 4.7 0.6 4.0 0.2 0.4 11.5 0.3 0.2 0.1 33.3 176.7 0.7 0.3 0.2 0.2 0.3 6.9 0.0 0.4 0.3 0.3 6.7 2.7 5.9 3.3 1.0 0.4 0.3 15.0 0.3 0.4 0.3 3.9 0.3 0.2 0.2 8.1 0.3 0.3 0.2 0.2 0.0 0.3 2.8 0.4 0.0 0.0 5.1 0.0 2.9 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 13.1 3.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 44.9 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 5.1 0.2 0.6 0.2 0.5 0.2 0.1 0.2 0.2 0.3 0.2 HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699008-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 116.9" "Cell line enhanced" "Detected in some" "ASC TERT1: 44.8;HHSteC: 35.1;HL-60: 19.6;hTEC/SVTERT24-B: 22.0;Karpas-707: 60.7;U-87 MG: 16.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "basophil: 33.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 33.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved Approved Centrosome,Cytosol "Secreted to blood" Cytosol Centrosome "CAB010333: AB_647965, HPA040360: , HPA044088: " "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavourable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" 6.2 10.6 1.4 2.9 1.2 4.6 4.8 0.5 4.5 5.1 4.0 0.4 2.9 1.5 5.2 3.1 2.9 4.0 7.1 9.3 3.6 1.3 7.3 27.5 15.8 2.0 1.3 1.4 3.2 1.4 1.6 4.3 116.9 1.9 10.8 1.9 2.0 2.2 3.2 1.4 0.9 1.8 15.1 6.0 6.6 2.3 2.0 0.9 0.5 5.3 1.4 1.4 10.5 21.5 0.0 2.0 33.5 7.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 5.5 44.8 0.0 0.1 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 35.1 19.6 0.1 10.6 0.0 22.0 0.0 0.5 0.0 60.7 0.1 0.0 0.0 13.6 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.8 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 16.1 4.1 0.0 33.5 6.6 1.6 0.0 7.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.3 0.0 6.7 0.4 0.0 1.5 1.4 1.2 0.5 4.5 3.6 1.3 1.3 1.4 1.9 0.9 HGFAC "HGFA, HGFAP" ENSG00000109758 "HGF activator" Q04756 4 3441887-3449495 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 141 "liver: 128.0" "Cell line enriched" "Detected in some" 8 "Hep G2: 10.7" "Cancer enriched" "Detected in some" 22 "liver cancer: 26.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058279, HPA059076" Enhanced "Secreted to blood" 7586667 11000000000 "HPA058279: AB_2683665, HPA059076: AB_2683898" "unprognostic (2.70e-2)" "unprognostic (8.20e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-2)" "unprognostic (2.85e-3)" "unprognostic (5.37e-3)" "unprognostic (5.90e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-3)" "unprognostic (5.52e-2)" "prognostic unfavourable (9.31e-4)" "unprognostic (2.87e-1)" "unprognostic (2.24e-1)" "unprognostic (9.49e-2)" "unprognostic (3.74e-4)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 128.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.2 1.2 0.7 0.4 0.1 0.0 0.0 0.6 1.1 0.0 0.0 0.3 0.1 0.0 0.0 0.5 0.7 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 HGSNAT "FLJ32731, HGNAT, TMEM76" ENSG00000165102 "Heparan-alpha-glucosaminide N-acetyltransferase" Q68CP4 8 43140455-43202855 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease mutation, Mucopolysaccharidosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029578 Approved "HPA029578: AB_10602423" "unprognostic (5.35e-2)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" "unprognostic (1.36e-1)" "prognostic unfavourable (5.46e-4)" "unprognostic (3.94e-3)" "unprognostic (1.10e-1)" "unprognostic (6.54e-3)" "unprognostic (5.02e-2)" "prognostic favourable (6.33e-5)" "unprognostic (2.55e-2)" "unprognostic (5.48e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "unprognostic (3.45e-2)" 24.8 16.9 21.4 16.0 18.8 16.0 29.6 18.5 20.6 28.5 17.8 20.3 24.5 15.4 27.5 29.7 20.4 24.0 22.1 18.7 18.0 16.5 16.9 19.9 21.8 14.9 12.9 19.8 31.1 28.8 26.5 24.8 25.6 15.7 21.6 14.7 20.9 20.7 20.7 11.9 29.5 18.1 25.3 18.2 14.9 18.6 8.5 11.7 9.1 21.9 18.4 18.2 21.1 23.2 2.3 14.5 8.3 8.0 8.2 3.1 4.0 11.5 15.6 3.9 7.9 32.3 24.4 5.9 13.2 15.7 9.6 8.6 2.2 17.0 7.0 9.2 18.4 6.7 1.7 8.0 5.6 2.8 3.2 6.9 9.9 3.9 10.4 1.5 1.1 16.3 11.5 5.3 11.1 17.0 3.1 9.9 17.5 5.2 6.2 3.0 3.7 2.3 0.7 7.2 3.4 15.8 9.8 2.1 6.2 17.2 5.5 7.6 19.1 8.9 19.9 14.8 2.5 9.2 5.4 8.0 7.5 2.6 11.9 2.7 9.0 0.2 8.0 8.3 2.8 5.0 3.1 1.8 2.3 2.8 14.5 2.3 1.7 1.9 3.0 8.2 7.2 1.9 1.5 4.0 21.4 18.8 18.5 20.6 18.0 16.5 12.9 19.8 15.7 11.7 HIBADH NS5ATP1 ENSG00000106049 "3-hydroxyisobutyrate dehydrogenase" P31937 7 27525442-27662995 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019522, HPA021002" Enhanced 780000 "HPA019522: AB_1850690, HPA021002: AB_1850692" "unprognostic (6.76e-2)" "unprognostic (1.09e-1)" "unprognostic (7.50e-2)" "unprognostic (9.79e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-3)" "unprognostic (7.22e-3)" "unprognostic (3.14e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" "unprognostic (2.05e-2)" "prognostic favourable (5.56e-11)" "unprognostic (2.49e-2)" "unprognostic (5.47e-2)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" 17.7 40.3 8.4 9.4 10.0 2.1 23.8 9.3 9.2 13.7 16.5 8.7 8.3 10.0 15.3 12.0 8.8 14.0 11.9 36.2 6.7 7.4 45.8 56.5 8.3 8.3 9.8 7.0 12.6 20.2 24.8 12.5 27.7 10.6 15.8 10.3 19.6 15.5 14.8 31.4 7.5 17.2 19.6 7.5 6.6 11.6 14.5 7.2 8.1 26.3 17.7 5.6 15.2 10.8 12.5 12.9 5.4 14.7 14.0 17.2 11.1 19.3 12.5 7.7 13.1 21.3 31.2 8.8 13.3 22.5 12.9 14.5 6.8 20.8 8.0 10.9 21.6 17.2 9.3 17.7 17.2 5.6 11.1 4.5 17.8 25.8 19.4 5.4 4.4 29.4 14.5 9.6 29.4 18.6 16.0 7.8 30.7 7.7 5.7 8.0 8.3 17.9 5.9 8.7 8.2 26.5 12.6 8.6 8.7 25.6 41.3 18.0 20.0 10.9 11.1 7.7 15.8 12.7 7.7 15.2 10.5 4.8 11.7 17.1 21.9 2.3 11.7 5.4 12.0 14.7 16.1 12.5 13.4 13.7 12.9 11.4 17.2 13.9 2.1 14.0 13.4 5.9 8.4 11.1 8.4 10.0 9.3 9.2 6.7 7.4 9.8 7.0 10.6 7.2 HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541" Enhanced Approved Nucleoplasm,Mitochondria 90000 "Nucleoplasm, Mitochondria" "HPA036540: AB_10673355, HPA036541: AB_2675182" "unprognostic (3.60e-3)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.36e-3)" "unprognostic (3.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "prognostic favourable (1.22e-4)" "unprognostic (7.32e-2)" "unprognostic (1.37e-2)" "prognostic favourable (1.04e-10)" "unprognostic (1.34e-1)" "unprognostic (3.73e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-3)" 13.7 38.6 18.1 10.1 19.5 5.0 15.8 16.4 18.7 16.3 15.8 14.5 13.0 24.7 17.0 13.0 20.2 10.2 10.0 13.7 18.5 12.7 65.7 56.8 7.6 8.2 20.1 10.8 9.5 29.5 35.8 24.7 7.8 21.0 11.7 18.7 15.0 10.6 12.2 17.5 23.7 16.5 11.3 18.2 9.0 10.4 10.6 22.2 10.5 17.4 15.4 9.3 12.5 49.2 24.2 15.1 14.6 7.6 17.3 20.0 7.3 9.8 7.5 16.2 10.2 15.2 13.5 8.9 10.6 5.7 10.0 10.9 23.3 8.7 14.8 15.1 9.1 18.7 17.1 14.5 15.1 21.3 13.3 19.8 15.8 20.4 5.2 14.1 7.4 10.9 7.9 11.7 2.1 16.2 24.0 13.0 10.9 9.0 14.3 16.2 5.1 15.4 17.9 11.6 37.7 22.6 29.7 12.3 11.6 9.2 13.1 29.9 14.8 11.0 11.5 10.6 9.9 7.1 7.4 8.3 17.7 12.4 9.7 12.3 8.3 12.9 6.7 14.6 11.9 7.6 12.8 24.2 13.3 12.5 11.1 18.7 14.2 18.2 3.5 17.3 5.7 15.1 20.0 7.3 18.1 19.5 16.4 18.7 18.5 12.7 20.1 10.8 21.0 22.2 HIF1AN "DKFZp762F1811, FIH1, FLJ20615, FLJ22027" ENSG00000166135 "Hypoxia inducible factor 1 alpha subunit inhibitor" Q9NWT6 10 100529072-100559998 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048742, HPA065302, CAB069903" Supported Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB069903: AB_10000508, HPA048742: , HPA065302: " "unprognostic (4.07e-2)" "unprognostic (7.75e-2)" "unprognostic (2.35e-2)" "unprognostic (3.83e-2)" "unprognostic (1.67e-2)" "unprognostic (1.21e-1)" "unprognostic (8.07e-3)" "unprognostic (8.82e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-3)" "unprognostic (1.54e-2)" "unprognostic (3.05e-2)" "unprognostic (3.01e-2)" "unprognostic (3.09e-2)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (3.24e-2)" 8.8 12.7 11.6 11.9 10.8 7.6 12.9 9.5 14.1 9.2 10.7 11.5 8.8 9.7 11.6 10.4 11.1 9.6 12.5 16.0 10.2 9.4 10.3 8.8 9.3 12.3 13.0 9.5 14.5 14.3 17.1 10.6 10.2 10.8 10.7 9.3 9.2 10.6 12.1 46.8 13.3 10.6 14.9 9.7 11.1 10.0 17.9 10.3 13.5 8.1 14.8 12.3 10.8 10.8 9.7 8.5 16.9 14.0 10.1 11.3 9.3 9.2 9.8 13.2 13.2 20.5 8.5 11.5 9.8 23.8 14.6 17.3 15.1 7.9 9.9 9.0 14.7 10.8 11.6 8.8 16.0 10.9 7.0 9.5 8.6 11.5 10.6 11.3 12.6 8.3 9.0 14.2 15.6 8.2 4.1 5.6 16.4 9.7 12.1 7.4 4.3 4.7 8.8 16.3 4.8 10.2 12.3 5.1 8.3 8.5 5.2 9.2 17.8 6.2 6.9 7.5 9.8 7.3 9.8 7.7 7.7 7.7 12.4 9.3 5.6 13.1 8.8 16.9 9.8 12.4 9.6 9.7 10.1 9.0 8.5 7.5 9.8 9.9 9.3 10.1 14.0 3.1 11.3 9.3 11.6 10.8 9.5 14.1 10.2 9.4 13.0 9.5 10.8 10.3 HIPK1 "KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2" ENSG00000163349 "Homeodomain interacting protein kinase 1" Q86Z02 1 113929192-113977869 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 90.1" "Cell line enhanced" "Detected in all" "MCF7: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016664 Approved Approved Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Centrosome, Cytosol" "HPA016664: AB_1850725" "unprognostic (2.98e-1)" "unprognostic (3.94e-2)" "unprognostic (4.89e-3)" "unprognostic (2.52e-2)" "unprognostic (6.47e-2)" "unprognostic (9.84e-3)" "unprognostic (4.64e-3)" "unprognostic (7.22e-2)" "unprognostic (7.52e-2)" "unprognostic (1.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (8.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.64e-1)" "unprognostic (1.94e-2)" "unprognostic (1.99e-2)" 15.1 16.8 21.2 14.7 23.0 90.1 13.6 38.1 20.4 20.4 14.4 20.7 14.5 10.2 15.5 14.2 18.7 27.3 17.5 27.9 22.9 17.2 14.8 13.8 19.3 14.7 15.0 16.4 18.7 16.8 20.7 23.8 13.8 21.3 14.4 15.2 20.7 13.0 14.9 19.7 18.5 13.4 15.1 18.3 15.9 14.8 33.5 21.3 47.2 23.3 13.1 15.5 17.3 26.7 2.3 6.2 9.8 4.2 4.3 6.0 2.3 8.1 6.6 9.2 7.0 10.8 5.7 6.2 5.6 6.8 8.0 7.7 7.6 3.1 10.9 7.7 8.9 5.5 11.8 6.6 11.6 7.9 6.0 15.9 8.3 8.0 9.0 12.7 19.7 6.1 9.6 10.2 10.5 11.8 10.8 11.8 11.5 61.5 16.6 7.2 9.4 5.9 10.1 27.0 3.8 7.2 7.0 4.1 5.4 10.2 11.0 7.2 6.4 18.3 11.5 7.9 10.7 12.8 8.5 7.4 5.8 9.5 8.8 10.3 17.9 3.4 4.2 8.2 5.5 3.7 5.2 1.7 4.9 4.9 3.1 2.3 5.0 6.0 9.8 4.3 2.6 6.2 3.6 2.3 21.2 23.0 38.1 20.4 22.9 17.2 15.0 16.4 21.3 21.3 HIPK2 ENSG00000064393 "Homeodomain interacting protein kinase 2" Q9H2X6 7 139561570-139777778 "Enzymes, Plasma proteins, Predicted membrane proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.1" "Cell line enhanced" "Detected in many" "HDLM-2: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 17.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007611 Supported Supported Nucleoplasm Nucleoplasm "HPA007611: AB_1850730" "unprognostic (1.35e-3)" "unprognostic (1.49e-2)" "unprognostic (1.65e-1)" "unprognostic (7.65e-2)" "unprognostic (5.50e-2)" "unprognostic (9.44e-2)" "unprognostic (2.76e-1)" "unprognostic (4.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.76e-2)" "unprognostic (3.42e-3)" "unprognostic (4.58e-2)" "prognostic favourable (9.99e-4)" "unprognostic (1.38e-1)" "unprognostic (7.82e-2)" "unprognostic (3.93e-3)" "unprognostic (1.03e-2)" 19.6 9.8 58.8 7.4 53.6 14.4 12.6 8.5 39.8 5.5 7.4 54.5 5.2 8.2 4.7 5.2 10.2 9.9 5.5 30.5 60.0 39.9 28.2 17.5 8.6 5.3 66.1 16.4 6.6 12.3 17.2 7.6 10.8 26.4 10.7 5.8 9.4 11.5 7.1 21.6 3.2 6.2 4.8 56.2 7.3 15.4 2.6 38.6 1.7 10.4 2.8 4.9 6.8 7.4 0.6 0.5 17.8 2.9 0.2 1.4 0.5 4.1 18.2 8.4 5.2 20.7 14.8 1.0 2.2 2.2 2.5 2.6 1.3 2.2 0.0 5.3 4.2 0.2 3.8 5.9 6.4 42.0 1.6 18.7 3.0 6.5 11.6 5.1 5.1 22.6 3.9 11.7 17.6 6.3 10.8 5.2 19.5 3.1 6.4 3.7 2.1 12.5 7.7 4.6 0.5 11.6 0.7 5.1 4.7 5.1 0.1 2.6 2.9 2.1 21.2 8.9 4.3 10.3 11.1 25.4 15.1 3.7 18.3 2.7 4.8 17.8 1.1 2.7 0.2 0.9 0.3 0.6 0.5 0.1 0.5 0.3 1.4 0.4 1.5 0.2 2.9 0.2 0.0 0.5 58.8 53.6 8.5 25.2 60.0 39.9 66.1 16.4 26.4 38.6 HIPK3 "DYRK6, FIST3, PKY, YAK1" ENSG00000110422 "Homeodomain interacting protein kinase 3" Q9H422 11 33256672-33357023 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028069 Approved Supported "Nuclear bodies,Cytosol" Cytosol "Nuclear bodies" "HPA028069: AB_10601815" "unprognostic (2.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.61e-1)" "unprognostic (5.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.78e-2)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.78e-1)" "unprognostic (2.18e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-3)" "unprognostic (7.89e-3)" "unprognostic (1.80e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" 46.3 13.4 12.7 15.9 15.9 12.7 49.2 11.7 13.7 23.6 24.8 11.9 15.9 9.9 28.3 22.8 22.9 24.1 18.8 69.0 13.4 11.8 23.4 21.1 20.2 20.9 15.5 8.2 23.6 15.4 49.7 21.2 20.5 15.2 23.2 12.8 15.6 18.8 18.1 45.9 18.7 25.0 32.9 15.9 20.1 20.5 14.7 14.2 15.2 37.9 26.0 14.4 33.6 34.6 3.1 11.3 17.6 10.1 3.3 4.4 3.7 9.4 9.0 6.8 7.7 31.6 20.0 6.8 10.0 11.6 8.1 6.9 9.9 6.9 10.2 8.5 12.2 12.1 5.1 11.2 11.5 14.8 8.0 10.3 10.2 7.5 13.1 11.0 6.5 18.7 22.0 3.1 9.2 9.9 3.2 20.5 13.1 4.9 9.1 7.7 1.7 5.5 12.3 24.2 10.2 13.4 14.8 1.0 5.7 13.6 15.6 9.3 17.5 20.4 12.7 12.8 8.8 14.7 7.1 11.3 17.7 10.8 6.2 11.7 11.9 6.6 10.1 4.8 3.5 7.6 4.4 2.4 3.2 3.7 11.3 3.1 2.9 3.5 17.6 3.3 8.6 1.4 3.2 3.7 12.7 15.9 11.7 13.7 13.4 11.8 15.5 8.2 15.2 14.2 HIPK4 FLJ32818 ENSG00000160396 "Homeodomain interacting protein kinase 4" Q8NE63 19 40379271-40390187 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 34.7" "Cell line enhanced" "Detected in some" "A549: 3.0;AN3-CA: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027733 Uncertain "HPA027733: AB_1850734" "unprognostic (2.07e-2)" "unprognostic (6.25e-2)" "unprognostic (2.58e-2)" "unprognostic (5.53e-3)" "unprognostic (4.00e-2)" "unprognostic (1.36e-1)" "unprognostic (3.69e-2)" "unprognostic (2.52e-3)" "unprognostic (1.08e-1)" "unprognostic (7.48e-3)" "unprognostic (8.85e-2)" "unprognostic (9.09e-2)" "unprognostic (3.06e-2)" "unprognostic (8.71e-3)" "unprognostic (3.64e-2)" "unprognostic (2.03e-2)" "unprognostic (4.63e-2)" 0.3 0.1 2.3 0.3 7.4 0.2 0.3 1.2 5.7 0.3 0.3 0.3 0.3 0.2 0.4 0.3 0.5 0.2 0.3 0.8 2.9 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.1 0.3 0.3 0.3 0.3 0.1 0.3 0.4 0.3 1.4 0.2 0.3 0.3 0.3 0.3 0.1 34.7 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.0 0.7 0.0 0.4 1.1 0.3 0.1 0.1 3.0 0.2 2.3 0.1 0.3 0.0 0.7 1.1 0.8 0.4 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.5 1.2 0.3 0.3 0.1 0.3 0.0 0.2 0.7 0.1 0.1 0.1 0.4 0.1 0.3 0.3 0.0 0.4 0.0 0.3 0.4 0.1 0.0 0.4 0.1 0.6 1.3 1.2 1.1 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 2.3 7.4 1.2 3.5 2.9 0.3 0.3 0.3 0.3 0.3 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052, HPA011956" Supported Supported Mitochondria 16000000 Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049, HPA011956: AB_1850758" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavourable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 17.5 10.5 21.1 19.9 30.4 23.5 15.8 40.0 48.6 16.6 16.9 10.1 7.6 6.3 13.5 9.4 44.8 15.2 12.6 61.6 19.8 23.3 10.8 4.4 17.2 14.3 19.8 31.3 9.0 4.6 12.5 14.7 22.6 31.3 25.5 15.4 21.2 21.5 26.8 62.1 30.7 8.6 25.6 9.7 13.3 20.3 28.9 10.6 18.9 33.6 32.6 23.0 25.8 23.1 11.4 25.5 17.8 39.3 8.9 23.0 29.6 17.4 9.9 13.3 12.7 14.9 11.2 8.5 17.4 45.8 23.3 25.2 2.9 1.9 1.2 13.8 29.1 15.3 12.4 38.9 22.3 11.6 9.7 43.4 10.6 0.2 17.0 0.8 32.9 16.9 22.7 33.3 74.5 24.1 72.3 9.2 31.9 28.9 5.0 2.2 20.4 44.3 7.7 8.1 0.1 16.1 20.6 13.7 16.1 19.9 38.7 11.5 21.1 2.8 24.7 34.8 15.9 19.1 24.2 11.0 7.2 3.0 45.1 22.8 10.0 17.8 27.3 13.4 14.0 39.3 23.0 11.4 16.2 15.8 25.5 6.8 14.5 11.5 6.6 8.9 39.3 2.9 17.8 29.6 21.1 30.4 40.0 48.6 19.8 23.3 19.8 31.3 31.3 10.6 HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74833981-74893359 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 26.2" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028587 Enhanced "HPA028587: AB_10602605" "unprognostic (1.28e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (7.21e-2)" "prognostic unfavourable (3.65e-4)" "unprognostic (2.85e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (4.43e-3)" "unprognostic (2.24e-2)" "prognostic unfavourable (1.37e-4)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" 27.0 2.2 4.4 9.5 5.0 20.4 10.8 0.7 4.5 5.3 23.2 7.3 5.7 1.3 2.6 40.1 13.6 4.8 9.1 8.3 2.8 2.3 2.1 1.4 16.5 5.0 8.5 1.1 14.9 3.5 1.1 1.7 13.2 5.4 4.0 19.2 9.6 10.3 0.5 29.3 9.7 8.9 1.7 10.9 7.4 8.7 24.8 7.4 4.3 7.1 22.3 9.2 29.0 8.3 0.8 6.2 26.2 7.1 0.0 0.8 2.0 16.2 0.1 3.8 13.7 32.3 3.4 14.0 6.3 9.2 7.1 10.3 13.0 2.9 11.8 6.1 2.9 5.6 17.2 13.3 20.8 3.3 3.7 16.0 3.7 17.8 10.2 23.3 26.3 5.6 14.5 13.6 23.8 3.4 13.9 0.0 2.0 11.5 5.6 23.9 13.6 11.3 9.2 7.9 9.2 4.3 22.9 2.7 13.4 4.0 20.4 8.0 1.0 3.7 2.7 22.8 4.0 9.4 11.4 8.1 2.3 5.9 53.2 17.1 5.8 6.6 7.1 26.2 0.1 5.7 0.3 0.6 0.4 0.1 6.2 0.8 0.7 0.7 5.9 0.0 3.7 0.1 0.8 2.0 4.4 5.0 0.7 4.5 2.8 2.3 8.5 1.1 5.4 7.4 HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899332 "Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 76.2;bone marrow: 55.0;lymphoid tissue: 40.6" "Cell line enriched" "Detected in some" 4 "U-937: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "basophil: 76.2" "Group enriched" "Detected in many" 11 "granulocytes: 76.2;monocytes: 31.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056743 Enhanced 1700000 "HPA056743: " "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavourable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" 9.2 2.6 0.6 8.5 1.0 55.0 1.3 0.3 1.2 0.4 1.7 0.3 0.0 0.9 0.8 2.6 1.9 3.0 0.9 5.4 0.6 0.3 1.6 4.1 16.3 24.1 1.2 0.5 1.2 1.0 0.0 0.4 2.9 0.5 0.9 0.6 0.9 0.9 0.1 0.8 0.3 1.6 3.4 0.6 40.6 1.2 0.6 0.2 1.3 1.5 0.2 1.2 1.8 5.3 0.0 5.1 76.2 31.4 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.6 0.1 0.2 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 20.8 0.0 76.2 15.4 32.9 0.0 29.5 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 5.4 0.0 31.4 0.2 0.0 6.0 0.6 1.0 0.3 1.2 0.6 0.3 1.2 0.5 0.5 0.2 HKDC1 "FLJ22761, FLJ37767" ENSG00000156510 "Hexokinase domain containing 1" Q2TB90 10 69220303-69267559 "Enzymes, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 77.4" "Cell line enhanced" "Detected in some" "A549: 14.7;CACO-2: 20.9;CAPAN-2: 41.4;EFO-21: 12.8;Hep G2: 12.1;RPTEC TERT1: 30.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 8.3;T-reg: 6.6" "Lineage enriched" "Detected in single" 29 "T-cells: 8.3" "Region enhanced" "Detected in some" "cerebral cortex: 12.2" "Low region specificity" "Detected in all" "HPA011956, HPA064198, HPA064230" Approved Enhanced Mitochondria Mitochondria "HPA011956: AB_1850758, HPA064198: , HPA064230: " "unprognostic (1.29e-2)" "unprognostic (2.26e-2)" "unprognostic (1.86e-1)" "unprognostic (8.47e-2)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (6.31e-3)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (3.11e-1)" "unprognostic (1.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.24e-1)" "unprognostic (2.10e-3)" "unprognostic (2.19e-1)" 0.2 0.0 0.9 1.2 1.6 0.0 0.2 0.8 1.4 0.5 29.8 0.5 0.2 29.9 0.5 1.0 0.3 2.5 11.2 0.2 0.5 0.6 15.6 4.6 1.3 0.3 0.3 0.2 1.0 4.7 0.0 0.5 0.2 0.4 0.2 2.3 12.0 0.2 0.2 0.2 0.0 77.4 0.2 0.2 0.2 0.4 0.6 0.2 0.2 5.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.2 8.3 1.6 0.4 14.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.9 41.4 0.0 12.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 12.1 1.0 0.0 0.0 0.0 0.1 0.1 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 30.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.1 0.2 0.0 0.0 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.7 0.0 4.4 1.4 0.0 0.0 8.3 3.2 0.0 0.2 0.0 0.0 6.6 1.6 0.9 1.6 0.8 0.4 0.5 0.6 0.3 0.2 0.4 0.2 HLCS HCS ENSG00000159267 "Holocarboxylase synthetase" P50747 21 36750888-36990236 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ligase, Multifunctional enzyme" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017379 Approved Supported Cytosol Cytosol "HPA017379: AB_1850768" "prognostic unfavourable (7.72e-4)" "unprognostic (2.41e-1)" "unprognostic (3.93e-2)" "unprognostic (2.05e-1)" "unprognostic (2.75e-1)" "unprognostic (1.44e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-1)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.44e-2)" "unprognostic (2.43e-1)" "unprognostic (2.55e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-3)" "unprognostic (3.02e-1)" 6.3 9.6 7.1 9.8 10.3 2.9 10.6 12.2 8.5 7.7 7.2 10.3 12.1 5.7 6.4 9.4 7.1 8.1 9.9 5.3 8.4 8.0 9.1 16.4 6.7 5.8 10.2 6.0 5.5 15.6 23.3 23.9 9.9 9.4 12.8 6.4 11.7 9.9 11.6 13.5 4.3 8.1 7.3 10.6 4.5 7.6 7.7 5.1 4.9 14.3 6.1 8.0 9.2 4.9 3.9 5.3 3.2 10.0 8.5 7.8 2.9 17.6 6.5 9.9 7.2 11.8 10.8 9.7 10.8 10.4 4.9 5.5 7.1 8.4 9.6 5.2 15.5 6.0 5.0 8.2 4.4 19.0 10.3 14.1 6.4 4.5 14.1 7.6 7.4 8.5 12.7 7.4 19.9 6.2 15.3 24.5 12.4 10.7 3.4 3.5 15.5 9.2 6.0 5.6 7.8 7.6 17.8 7.0 7.2 14.2 6.6 10.8 11.5 7.8 8.3 7.1 2.2 6.5 5.8 23.8 14.5 5.9 10.2 9.6 8.2 3.2 2.1 1.6 7.8 4.0 6.1 2.6 4.5 5.2 2.0 3.9 5.4 5.5 2.7 8.5 10.0 5.3 2.7 2.9 7.1 10.3 12.2 8.5 8.4 8.0 10.2 6.0 9.4 5.1 HLTF "HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3" ENSG00000071794 "Helicase like transcription factor" Q14527 3 149030127-149086554 "Enzymes, Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015284, HPA049001" Uncertain Supported Nucleoplasm Nucleoplasm "HPA015284: AB_1857263, HPA049001: " "unprognostic (3.21e-2)" "unprognostic (3.46e-2)" "unprognostic (6.81e-2)" "unprognostic (1.95e-3)" "unprognostic (4.29e-1)" "unprognostic (1.29e-1)" "prognostic unfavourable (7.27e-4)" "unprognostic (3.01e-2)" "unprognostic (2.13e-2)" "unprognostic (2.27e-1)" "unprognostic (4.78e-2)" "unprognostic (9.00e-3)" "unprognostic (1.39e-1)" "unprognostic (2.94e-1)" "unprognostic (3.42e-1)" "unprognostic (2.83e-2)" "unprognostic (1.07e-2)" 10.2 22.1 12.6 8.4 17.6 9.0 12.4 29.3 23.8 11.1 11.0 12.4 6.2 4.8 12.4 9.6 7.1 10.8 8.6 16.5 15.8 16.6 15.6 16.3 7.1 9.8 15.7 19.0 17.6 12.0 16.5 25.1 7.3 29.9 14.7 7.0 11.3 9.3 11.1 9.7 5.1 6.6 12.7 19.0 7.5 8.7 37.7 14.0 17.1 19.0 4.8 9.6 10.0 7.8 8.4 9.2 8.8 2.3 5.4 10.4 3.5 24.6 12.0 17.1 13.3 11.4 14.9 1.7 16.7 10.0 12.4 14.5 9.7 17.2 15.9 20.4 7.7 0.7 22.9 6.6 20.7 8.7 11.2 38.2 9.4 3.9 7.1 10.0 15.8 9.4 3.6 9.2 5.4 7.1 13.3 10.4 16.9 12.4 20.5 15.4 12.9 15.1 23.7 19.3 2.5 10.2 8.0 16.9 10.0 25.3 11.7 22.9 35.2 9.8 5.0 14.5 8.8 20.5 18.1 15.3 8.6 20.8 14.3 13.7 5.6 8.8 1.3 4.0 5.6 2.1 10.4 8.4 4.9 7.2 3.9 5.4 7.2 7.4 0.2 5.4 2.3 9.2 4.4 3.5 12.6 17.6 29.3 23.8 15.8 16.6 15.7 19.0 29.9 14.0 HM13 "dJ324O17.1, H13, IMP1, IMPAS, PSENL3, PSL3, SPP, SPPL1" ENSG00000101294 "Histocompatibility minor 13" Q8TCT9 20 31514428-31577923 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045089, HPA056062" Enhanced Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA045089: AB_10962054, HPA056062: " "unprognostic (8.03e-2)" "unprognostic (2.11e-2)" "unprognostic (5.03e-2)" "unprognostic (1.59e-1)" "unprognostic (2.82e-1)" "unprognostic (5.87e-3)" "prognostic unfavourable (1.95e-5)" "unprognostic (2.66e-2)" "unprognostic (2.14e-2)" "unprognostic (2.55e-1)" "unprognostic (2.30e-1)" "unprognostic (8.10e-2)" "prognostic unfavourable (4.64e-12)" "unprognostic (3.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-1)" "unprognostic (8.17e-2)" 25.2 34.3 9.2 20.1 11.1 19.8 36.4 10.2 17.5 37.9 17.0 13.2 64.7 18.1 23.3 40.7 39.2 21.4 24.1 17.9 9.3 13.0 30.2 121.3 25.5 38.7 10.8 9.8 20.8 132.3 24.4 28.6 45.9 14.5 22.4 16.3 15.4 149.6 84.3 13.1 15.0 17.8 17.9 11.0 22.0 25.3 11.7 9.0 15.5 33.5 21.5 30.5 18.1 21.4 16.7 48.2 50.1 65.3 19.4 29.8 52.6 24.6 26.0 10.5 15.5 47.9 30.8 36.2 42.2 39.5 28.9 29.8 51.6 29.7 15.9 56.9 46.0 45.1 14.7 28.4 19.0 8.0 19.9 35.2 19.0 31.0 53.3 20.0 14.1 28.1 18.5 24.4 33.4 22.3 15.5 63.3 26.7 29.1 17.1 14.4 12.1 44.6 10.9 49.5 74.2 27.8 13.2 13.8 16.7 43.2 41.6 34.1 32.3 19.1 27.0 43.9 23.4 44.2 23.7 40.9 24.3 12.6 59.9 72.2 38.7 18.4 65.3 31.8 21.7 64.0 29.8 16.7 20.5 20.9 46.0 12.6 13.8 16.2 50.1 19.4 58.6 48.2 18.1 52.6 9.2 11.1 10.2 17.5 9.3 13.0 10.8 9.8 14.5 9.0 HMBS "PBGD, PORC, UPS" ENSG00000256269 "Hydroxymethylbilane synthase" P08397 11 119084866-119093549 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 75.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006114, HPA050659" Supported Approved "Lipid droplets" 28000000 "Lipid droplets" "HPA006114: AB_1079067, HPA050659: " "unprognostic (6.24e-2)" "unprognostic (9.10e-3)" "unprognostic (1.42e-2)" "unprognostic (4.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.30e-1)" "unprognostic (2.29e-3)" "unprognostic (2.81e-1)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (6.83e-2)" "unprognostic (5.06e-2)" "unprognostic (2.90e-3)" "unprognostic (3.91e-3)" "unprognostic (9.53e-2)" "unprognostic (1.32e-1)" "unprognostic (6.11e-2)" 5.5 11.0 5.3 6.2 9.3 75.2 8.6 5.2 8.0 5.5 8.3 6.0 6.0 7.9 6.9 7.9 9.4 5.5 6.4 11.5 5.9 5.5 9.9 22.2 5.8 14.5 8.8 4.5 3.7 21.2 7.9 5.9 9.7 8.4 5.5 9.2 4.1 10.1 7.2 17.4 6.0 7.9 6.8 9.7 10.4 7.1 7.4 7.5 6.0 8.4 13.0 9.3 5.7 4.8 7.7 19.1 12.0 14.0 3.8 7.4 9.4 9.1 14.0 6.7 11.9 5.4 6.7 10.1 7.3 8.3 10.8 9.3 17.3 14.5 14.2 16.4 9.3 13.0 10.0 14.2 6.9 9.7 10.2 23.3 5.6 12.6 9.9 8.7 7.6 7.3 9.1 17.0 13.0 5.0 34.5 6.3 8.5 36.8 8.4 16.8 7.5 8.9 9.7 6.6 13.8 10.8 8.4 7.4 10.1 5.9 9.2 6.4 15.7 12.1 4.6 8.2 6.2 8.0 8.5 3.4 4.0 8.4 5.4 11.5 9.7 12.0 14.0 1.4 5.1 12.2 6.7 7.7 4.8 5.7 19.1 7.2 7.4 5.6 0.4 3.8 7.3 12.3 4.9 9.4 5.3 9.3 5.2 8.0 5.9 5.5 8.8 4.5 8.4 7.5 HMGCL HL ENSG00000117305 "3-hydroxymethyl-3-methylglutaryl-CoA lyase" P35914 1 23801885-23838620 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 81.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004727 Enhanced "Intracellular and membrane" 120000 "HPA004727: AB_1079074" "unprognostic (8.24e-2)" "unprognostic (3.21e-2)" "prognostic favourable (7.67e-4)" "unprognostic (1.23e-3)" "unprognostic (5.47e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (3.05e-1)" "unprognostic (8.24e-2)" "prognostic favourable (5.07e-8)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (8.60e-2)" "unprognostic (3.39e-3)" 7.4 18.5 6.4 8.2 6.6 1.6 14.3 4.3 7.7 7.6 13.9 9.0 12.0 12.0 6.2 13.2 9.1 9.7 12.8 11.2 5.9 6.0 30.3 81.4 8.8 11.1 7.5 7.1 6.1 15.2 13.1 7.8 8.5 7.9 8.7 14.2 10.0 8.9 11.5 15.2 7.0 15.4 11.7 9.3 8.6 10.8 7.2 6.1 8.3 14.5 8.1 8.3 8.8 6.7 24.1 27.7 40.8 33.8 24.5 21.2 26.8 10.7 6.2 7.0 5.2 28.5 21.8 2.7 8.5 15.0 9.3 11.3 3.9 20.9 5.6 17.6 13.3 8.7 8.3 13.8 10.1 11.5 6.3 7.5 5.5 8.8 36.9 2.9 5.0 25.2 20.6 12.2 23.4 12.6 7.6 8.0 16.9 11.0 4.5 5.8 1.8 8.6 6.5 5.7 10.4 21.8 5.6 5.9 5.2 11.1 4.2 18.8 13.3 7.3 9.3 7.7 4.7 14.0 3.6 11.4 5.6 5.0 19.1 10.9 8.9 40.8 32.4 30.1 18.4 30.4 20.1 21.9 20.0 21.2 27.7 24.1 20.3 19.4 12.2 24.5 33.8 20.6 20.8 26.8 6.4 6.6 4.3 7.7 5.9 6.0 7.5 7.1 7.9 6.1 HMGCR ENSG00000113161 "3-hydroxy-3-methylglutaryl-CoA reductase" P04035 5 75336329-75362104 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008338, CAB016797" Approved "CAB016797: , HPA008338: AB_10960401" "unprognostic (5.07e-2)" "unprognostic (1.65e-2)" "unprognostic (3.65e-3)" "unprognostic (1.02e-2)" "unprognostic (1.65e-3)" "unprognostic (1.02e-1)" "unprognostic (1.45e-1)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "unprognostic (1.90e-2)" "unprognostic (1.41e-1)" "unprognostic (3.99e-2)" "prognostic favourable (9.42e-6)" "unprognostic (2.44e-1)" "unprognostic (2.55e-2)" "unprognostic (3.64e-3)" "unprognostic (4.37e-2)" 5.6 28.9 12.4 8.7 31.1 12.1 16.4 14.4 36.3 13.9 23.0 10.9 7.1 18.9 9.0 14.4 35.0 6.5 8.2 4.0 21.8 16.5 12.1 53.5 12.1 7.0 9.8 19.4 15.2 8.4 16.2 11.4 9.2 29.6 12.4 19.7 7.8 12.4 4.5 3.4 36.1 19.0 6.8 17.0 7.9 14.6 14.0 8.8 13.9 12.5 23.2 12.4 6.2 18.1 4.3 12.5 23.2 11.0 9.5 6.5 5.1 15.8 6.3 63.7 21.9 13.5 26.1 16.0 4.6 12.8 9.4 20.9 23.5 39.2 14.2 16.7 7.4 20.1 33.0 53.7 9.9 4.8 12.1 10.8 9.5 18.1 19.9 9.0 8.0 16.9 31.6 32.6 16.2 7.5 11.6 21.8 14.7 10.4 16.6 9.1 27.2 4.7 11.7 19.0 20.3 38.5 37.2 22.1 10.0 10.1 10.5 9.1 10.3 23.8 8.7 5.1 7.6 5.4 7.8 7.0 8.8 19.6 7.4 17.7 10.5 6.7 11.0 6.3 6.1 6.9 5.1 4.3 4.6 6.4 12.5 4.2 4.5 6.2 23.2 9.5 7.4 3.9 6.5 5.1 12.4 31.1 14.4 36.3 21.8 16.5 9.8 19.4 29.6 8.8 HMGCS1 HMGCS ENSG00000112972 "3-hydroxy-3-methylglutaryl-CoA synthase 1" Q01581 5 43289395-43313512 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 117.0" "Cell line enhanced" "Detected in all" "AF22: 123.5;HBEC3-KT: 71.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032907, HPA036913, HPA036914" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" 310000 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032907: AB_2118319, HPA036913: , HPA036914: AB_10671751" "unprognostic (1.31e-1)" "unprognostic (5.12e-3)" "unprognostic (6.82e-3)" "unprognostic (4.59e-2)" "unprognostic (8.39e-2)" "unprognostic (2.49e-2)" "unprognostic (1.03e-1)" "unprognostic (3.14e-2)" "unprognostic (1.27e-2)" "unprognostic (3.13e-1)" "unprognostic (6.40e-3)" "unprognostic (9.15e-2)" "prognostic favourable (3.87e-6)" "unprognostic (1.09e-1)" "unprognostic (9.22e-2)" "unprognostic (3.03e-2)" "unprognostic (2.37e-2)" 6.0 16.5 13.3 8.1 24.4 4.3 12.8 8.4 38.2 16.9 15.5 16.9 9.5 27.8 6.8 11.5 53.0 4.1 7.5 5.1 19.4 18.8 10.5 117.0 26.9 6.2 10.4 20.7 15.4 8.4 10.8 5.0 6.9 59.3 12.9 14.2 13.0 18.5 7.7 5.0 25.2 17.1 6.3 25.8 4.4 13.4 9.8 8.1 3.3 7.5 58.1 23.3 6.1 21.4 9.3 7.8 6.9 7.7 6.7 7.9 3.3 15.3 7.4 123.5 14.2 7.2 28.7 8.4 2.4 9.7 3.5 7.0 12.8 22.2 16.3 5.5 3.5 12.1 30.7 71.2 3.7 3.4 36.9 6.0 6.8 17.3 11.3 13.1 4.3 15.6 8.6 18.5 7.4 3.6 10.7 44.6 2.9 7.1 11.8 16.0 22.1 3.9 8.5 17.3 18.0 54.7 23.8 10.6 5.1 12.6 6.3 3.7 9.9 17.5 4.3 2.6 13.3 2.8 2.3 6.0 9.1 22.2 2.3 15.8 2.3 5.5 4.0 3.7 5.6 7.4 5.6 9.3 6.2 7.9 7.8 7.5 5.3 7.3 6.9 6.7 7.7 6.5 5.7 3.3 13.3 24.4 8.4 32.1 19.4 18.8 10.4 20.7 59.3 8.1 HMGCS2 ENSG00000134240 "3-hydroxy-3-methylglutaryl-CoA synthase 2" P54868 1 119747996-119768905 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 257.0" "Cell line enriched" "Detected in some" 16 "RT4: 66.2" "Cancer enhanced" "Detected in many" "liver cancer: 441.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027423, HPA027442, CAB032906" Enhanced Supported Mitochondria 820000 Mitochondria "CAB032906: AB_2118322, HPA027423: AB_2672266, HPA027442: AB_2672277" "unprognostic (2.57e-1)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "unprognostic (7.62e-2)" "unprognostic (1.49e-2)" "prognostic favourable (2.43e-7)" "unprognostic (9.68e-2)" "unprognostic (3.21e-2)" "prognostic favourable (2.17e-4)" "unprognostic (1.20e-1)" "unprognostic (6.42e-2)" "prognostic favourable (3.43e-5)" "unprognostic (9.57e-2)" "unprognostic (2.31e-1)" "unprognostic (5.00e-2)" "unprognostic (1.54e-3)" 0.3 0.1 0.3 8.7 0.3 0.0 20.6 0.3 0.3 0.3 30.8 0.4 0.3 13.8 0.3 0.3 0.7 0.1 4.4 42.0 0.4 0.0 7.4 257.0 0.8 0.3 0.3 0.3 0.3 1.4 0.0 0.3 0.8 0.7 3.8 19.8 18.9 5.1 0.3 1.4 1.8 12.2 1.9 0.3 0.3 8.1 6.1 0.3 0.4 0.3 0.6 2.1 7.4 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 66.2 0.0 0.2 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.3 0.4 0.0 0.3 0.3 0.7 0.3 HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 209.8" "Cell line enhanced" "Detected in many" "BEWO: 110.9;U-138 MG: 64.7;U-87 MG: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "classical monocyte: 17.7;intermediate monocyte: 40.5;non-classical monocyte: 53.4" "Lineage enriched" "Detected in many" 6 "monocytes: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" 17000 "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavourable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" 28.4 10.3 4.1 12.5 8.7 16.3 13.8 0.8 20.6 5.7 12.0 6.1 0.6 22.0 2.5 8.5 8.8 9.8 9.8 10.2 4.1 3.1 23.0 63.7 54.0 76.3 12.5 1.3 28.6 8.8 0.5 2.7 21.1 7.5 3.6 4.9 3.3 3.5 0.8 21.9 13.8 22.8 6.9 11.2 209.8 4.6 5.9 7.6 3.6 4.2 7.3 8.3 6.7 10.2 4.8 7.9 8.4 53.4 1.1 0.3 10.1 1.4 22.6 0.2 4.6 18.5 5.4 110.9 10.4 6.2 4.9 5.3 10.0 1.4 0.0 2.3 8.5 1.2 1.3 0.2 1.5 37.3 1.1 0.5 6.9 20.4 25.7 1.4 7.0 17.0 0.4 32.3 2.1 14.7 0.0 10.8 15.6 1.1 0.0 0.5 2.2 2.5 0.1 1.9 3.4 3.5 12.1 0.3 0.3 26.9 2.4 1.8 1.0 0.3 5.5 64.7 2.9 10.5 10.1 6.8 8.7 1.0 62.8 0.6 1.0 2.0 17.7 1.2 0.2 40.5 0.0 4.8 0.1 0.3 7.9 0.5 0.0 0.0 8.4 1.1 53.4 0.2 0.2 10.1 4.1 8.7 0.8 4.8 4.1 3.1 12.5 1.3 7.5 7.6 HMOX2 HO-2 ENSG00000103415 "Heme oxygenase 2" P30519 16 4474690-4510347 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025464, HPA040611" Supported Approved Vesicles,Cytosol 1200000 "Vesicles, Cytosol" "CAB025464: , HPA040611: AB_10961034" "unprognostic (3.33e-1)" "unprognostic (3.58e-2)" "unprognostic (1.11e-1)" "prognostic favourable (7.91e-4)" "unprognostic (2.74e-1)" "unprognostic (4.27e-2)" "unprognostic (6.23e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (3.60e-1)" "unprognostic (7.74e-3)" "unprognostic (9.87e-2)" "prognostic favourable (8.98e-6)" "unprognostic (3.51e-2)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (2.64e-1)" 19.4 19.2 32.1 15.7 50.7 13.6 16.6 19.7 38.6 13.3 17.9 22.9 12.2 23.5 11.9 18.7 36.6 15.6 19.7 57.2 29.3 22.0 32.2 39.7 15.8 20.8 27.3 35.1 12.5 22.4 20.6 14.7 12.5 36.5 12.1 19.9 8.6 16.0 10.0 20.1 16.6 19.3 16.6 27.2 23.3 29.7 48.1 28.2 8.7 13.8 16.7 25.3 16.5 15.0 14.5 14.5 48.7 8.9 18.7 35.8 25.8 24.6 10.5 6.3 13.6 18.8 9.7 10.5 17.0 8.4 14.5 12.6 13.3 16.8 11.4 19.2 15.6 14.9 19.7 36.5 16.5 14.6 13.4 8.3 10.1 18.0 12.7 18.0 14.2 15.1 12.3 16.8 12.3 26.6 13.4 5.8 13.3 30.5 14.8 14.1 9.6 10.0 15.7 11.0 24.0 20.1 16.2 10.6 6.2 13.6 28.9 18.3 18.0 10.1 25.9 8.2 12.2 35.1 8.7 7.2 8.9 25.2 5.2 14.9 10.4 13.7 7.4 48.7 35.2 8.9 29.9 14.5 32.7 35.8 14.5 13.0 31.7 32.7 26.1 18.7 6.5 8.2 30.0 25.8 32.1 50.7 19.7 38.6 29.3 22.0 27.3 35.1 36.5 28.2 HNMT ENSG00000150540 "Histamine N-methyltransferase" P50135 2 137964020-138016364 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 61.3;HSkMC: 25.1;RT4: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 34.6;intermediate monocyte: 26.7;myeloid DC: 20.9;non-classical monocyte: 14.6" "Group enriched" "Detected in many" 22 "dendritic cells: 20.9;monocytes: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035480, HPA035481, HPA073754" Approved Approved Nucleoplasm,Centrosome,Cytosol 64000 "Nucleoplasm, Cytosol" Centrosome "HPA035480: , HPA035481: AB_10672094, HPA073754: " "unprognostic (1.32e-1)" "unprognostic (3.53e-1)" "unprognostic (5.44e-2)" "unprognostic (2.09e-2)" "unprognostic (2.81e-1)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.43e-1)" "prognostic unfavourable (3.41e-4)" "unprognostic (5.24e-2)" "unprognostic (1.34e-2)" "unprognostic (1.76e-2)" "unprognostic (5.34e-2)" "unprognostic (1.21e-1)" "prognostic favourable (4.68e-4)" 41.4 5.8 12.2 12.3 11.1 3.3 28.8 10.7 11.3 27.6 16.3 8.6 13.9 8.7 22.2 21.4 11.6 14.6 21.6 14.7 12.7 7.8 33.4 74.2 21.9 17.0 13.7 9.2 33.1 14.1 24.5 5.5 14.3 11.2 22.3 17.7 8.7 14.1 20.1 4.9 8.1 11.1 13.2 14.8 18.5 11.5 11.7 14.6 1.0 7.3 8.5 6.5 21.3 12.0 0.5 20.9 1.2 34.6 0.1 0.2 9.2 0.2 0.3 1.5 4.1 17.6 18.9 0.1 1.1 1.7 0.1 0.7 7.8 4.4 0.2 13.9 4.6 0.4 3.2 0.0 0.0 0.2 1.6 0.1 13.1 61.3 7.9 0.0 0.2 25.1 0.0 6.2 0.0 4.4 0.2 0.3 13.2 1.0 0.0 0.2 7.8 1.6 0.1 0.5 0.0 18.9 31.8 0.1 0.4 6.0 7.7 0.0 0.2 14.4 1.3 1.3 3.4 1.8 4.4 0.1 0.0 0.2 6.0 7.5 0.9 0.8 34.6 0.2 0.2 26.7 0.1 0.5 0.1 0.1 20.9 0.3 0.1 0.2 1.2 0.1 14.6 0.6 0.2 9.2 12.2 11.1 10.7 11.3 12.7 7.8 13.7 9.2 11.2 14.6 HOGA1 "C10orf65, DHDPS2, DHDPSL, FLJ37472, NPL2" ENSG00000241935 "4-hydroxy-2-oxoglutarate aldolase 1" Q86XE5 10 97584323-97612802 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 39.8;liver: 31.0" "Group enriched" "Detected in some" 4 "AN3-CA: 6.0;EFO-21: 7.2;Hep G2: 18.5;RPTEC TERT1: 22.8" "Group enriched" "Detected in many" 5 "liver cancer: 4.5;renal cancer: 9.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039466 Approved 15000 "HPA039466: " "unprognostic (6.44e-2)" "unprognostic (3.64e-2)" "unprognostic (7.50e-2)" "unprognostic (2.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.29e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-3)" "unprognostic (4.72e-1)" "unprognostic (2.37e-1)" "unprognostic (1.28e-1)" "unprognostic (6.80e-2)" "prognostic favourable (9.08e-4)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (2.94e-3)" "unprognostic (7.20e-4)" 3.3 5.4 3.3 0.6 3.8 0.8 2.1 7.0 4.3 0.8 0.6 8.2 1.5 0.7 0.9 4.0 1.3 2.0 3.8 10.1 4.2 2.8 39.8 31.0 0.9 0.7 9.3 5.2 0.6 12.0 2.0 2.4 0.6 7.2 1.3 0.6 3.6 1.8 2.2 2.0 1.2 0.6 0.8 8.2 0.7 0.6 0.7 6.9 0.0 1.8 4.1 0.6 0.8 0.6 2.1 1.7 4.4 1.2 1.2 1.3 0.5 0.3 2.7 0.1 6.0 1.2 0.3 0.1 0.1 0.2 0.1 0.0 2.2 0.3 0.2 7.2 0.1 2.0 0.1 0.2 0.1 0.2 3.1 0.1 1.0 18.5 0.8 0.2 0.2 0.3 0.6 0.2 0.1 0.3 0.1 0.4 0.4 1.2 0.1 0.2 0.2 0.0 0.2 0.5 0.4 22.8 0.4 0.5 0.9 0.1 1.1 0.7 2.1 0.1 0.3 0.7 0.2 0.4 0.2 0.4 0.6 0.1 1.5 0.3 0.1 2.4 1.1 1.2 1.2 0.9 1.0 1.1 1.3 0.9 0.5 2.1 1.1 1.2 4.4 1.2 1.2 1.7 0.9 0.5 3.3 3.8 7.0 3.9 4.2 2.8 9.3 5.2 7.2 6.9 HP ENSG00000257017 Haptoglobin P00738 16 72054592-72061055 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Immunity" "Antibiotic, Antimicrobial, Antioxidant, Serine protease homolog" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "liver: 1156.9" "Group enriched" "Detected in some" 5 "Hep G2: 64.7;HSkMC: 37.1" "Cancer enriched" "Detected in many" 81 "liver cancer: 1297.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "classical monocyte: 20.0;eosinophil: 30.9" "Group enriched" "Detected in many" 7 "granulocytes: 30.9;monocytes: 20.0" "CAB003787, HPA047750" Enhanced Approved Vesicles "Secreted to blood" 181000000 140000000000 Vesicles "CAB003787: , HPA047750: " "unprognostic (6.38e-3)" "unprognostic (7.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.41e-2)" "unprognostic (2.34e-3)" "unprognostic (2.07e-1)" "unprognostic (7.79e-3)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "prognostic unfavourable (6.94e-13)" "unprognostic (4.34e-4)" "unprognostic (1.80e-1)" "unprognostic (6.61e-2)" "unprognostic (2.49e-2)" 9.8 0.0 0.3 0.4 0.3 4.4 0.3 0.3 0.3 1.5 0.4 0.3 0.3 0.0 0.3 0.5 0.3 1.1 0.3 3.0 0.3 0.0 0.4 1156.9 1.4 0.4 0.3 0.3 0.3 0.5 0.0 0.5 0.3 0.3 0.3 0.0 0.3 0.3 0.3 0.3 0.0 0.3 0.3 0.3 1.4 0.0 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.5 0.0 3.5 30.9 20.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.3 0.0 64.7 0.1 9.2 1.7 37.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.5 0.1 0.7 0.0 0.3 6.9 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 2.1 1.4 0.0 0.2 0.0 0.0 1.2 0.0 4.4 0.0 3.6 0.0 2.6 20.0 30.9 0.0 0.8 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 5.8 0.0 0.9 0.0 0.0 5.0 0.3 0.3 0.3 0.3 0.3 0.0 0.3 0.3 0.3 0.3 HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease mutation, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 267.5" "Cell line enriched" "Detected in some" 30 "Hep G2: 104.7" "Cancer enriched" "Detected in many" 100 "liver cancer: 540.9" "Region enriched" "Detected in single" 29 "pons and medulla: 13.7" "Group enriched" "Detected in many" 4 "eosinophil: 9.8;neutrophil: 4.8;plasmacytoid DC: 5.0" "Group enriched" "Detected in many" 5 "dendritic cells: 5.0;granulocytes: 9.8" "Region enriched" "Detected in single" 8 "amygdala: 0.4" "Low region specificity" "Detected in many" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" 23000000 "Nuclear speckles" "HPA038321: AB_2675957, HPA038322: AB_10670778" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.81e-3)" "unprognostic (1.42e-3)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (1.13e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (6.14e-3)" "unprognostic (9.72e-3)" "unprognostic (8.61e-3)" "unprognostic (7.16e-2)" "unprognostic (1.97e-1)" "unprognostic (4.12e-1)" "unprognostic (3.06e-2)" "unprognostic (2.34e-1)" 0.1 0.5 0.0 0.1 0.1 0.0 0.4 0.1 0.3 0.2 0.1 2.1 0.3 0.0 0.3 0.4 0.1 0.7 0.2 0.3 0.4 0.0 51.3 267.5 0.2 0.4 0.1 0.0 0.7 0.7 0.0 0.1 0.0 13.7 0.5 0.0 3.8 0.0 0.8 0.2 0.0 0.1 0.4 0.2 0.2 0.1 0.8 0.1 0.0 0.1 0.1 0.1 0.6 0.2 0.1 5.0 9.8 1.4 0.0 0.3 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.1 104.7 2.5 0.3 3.5 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.1 2.1 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.8 9.8 0.0 1.0 0.1 0.1 0.1 0.1 1.3 0.1 0.3 0.2 4.8 0.0 1.4 5.0 0.0 0.3 0.0 0.1 0.1 0.3 0.4 0.0 0.1 0.0 13.7 0.1 HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490177-174523154 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 193.3" "Cell line enhanced" "Detected in some" "A549: 27.3;ASC diff: 16.9;HEL: 59.7;RT4: 92.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Region enriched" "Detected in single" 4 "pons and medulla: 3.8" "Group enriched" "Detected in many" 5 "basophil: 37.7;T-reg: 15.1" "Group enriched" "Detected in many" 71 "granulocytes: 37.7;T-cells: 15.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favourable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" 5.1 2.6 0.5 7.9 0.6 0.0 24.6 0.4 0.6 23.0 73.3 0.5 2.5 22.9 13.4 7.5 32.0 4.5 10.7 1.2 0.6 0.7 8.5 63.7 22.9 7.9 0.8 0.5 2.3 0.4 0.0 0.9 193.3 3.8 20.1 8.4 4.6 3.0 1.1 1.6 15.3 64.5 9.3 0.5 2.9 36.3 1.9 0.5 5.5 0.4 5.0 7.9 61.2 31.8 0.1 0.2 37.7 0.1 0.3 15.1 1.0 0.0 27.3 0.0 0.0 16.9 1.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 2.5 2.5 0.0 0.0 0.0 0.5 59.7 2.0 0.0 0.0 0.3 0.1 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.4 2.8 0.0 0.2 5.6 92.8 0.1 0.1 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 37.7 0.1 5.4 3.7 0.0 5.7 0.1 1.9 1.6 0.2 0.0 0.6 1.5 0.4 0.3 0.0 0.0 15.1 1.0 0.5 0.6 0.4 0.6 0.6 0.7 0.8 0.5 3.8 0.5 HPGDS "GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS" ENSG00000163106 "Hematopoietic prostaglandin D synthase" O60760 4 94298535-94342876 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 24.8" "Group enriched" "Detected in some" 8 "HEL: 31.6;HMC-1: 9.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 25 "basophil: 15.8" "Lineage enriched" "Detected in single" 25 "granulocytes: 15.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA024035 Enhanced Approved Nucleoplasm,Vesicles,Cytosol 170000 "Vesicles, Cytosol" Nucleoplasm "HPA024035: AB_1855743" "unprognostic (5.71e-2)" "unprognostic (5.80e-3)" "unprognostic (1.17e-1)" "unprognostic (5.36e-3)" "unprognostic (2.76e-1)" "unprognostic (2.38e-4)" "unprognostic (1.01e-2)" "unprognostic (4.41e-3)" "unprognostic (1.35e-1)" "unprognostic (7.75e-4)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (5.15e-3)" "unprognostic (4.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.61e-2)" "unprognostic (6.14e-2)" 14.3 2.9 8.0 1.6 12.1 1.6 5.8 2.0 7.7 5.4 6.9 4.4 0.2 7.5 4.7 3.3 4.1 2.5 9.3 3.0 8.4 3.6 2.5 1.3 12.7 0.9 9.6 2.4 1.5 1.8 1.7 1.5 24.8 9.0 6.4 7.5 2.9 3.8 2.2 1.4 5.8 8.6 5.8 14.6 1.4 4.4 1.8 12.1 1.5 1.2 2.8 1.5 4.5 3.5 0.0 0.1 15.8 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 2.4 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 8.0 12.1 2.0 7.7 8.4 3.6 9.6 2.4 9.0 12.1 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066571 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "kidney: 55.4;liver: 146.5;pancreas: 80.1" "Group enriched" "Detected in some" 9 "EFO-21: 19.4;Hep G2: 27.5;T-47d: 13.4" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.2;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 5 "T-cells: 1.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved 1000000 "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favourable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 0.2 0.0 0.3 0.1 0.5 0.0 3.2 0.4 1.1 0.3 0.3 0.2 8.4 0.2 1.1 10.7 0.1 1.9 3.2 0.7 0.6 0.3 55.4 146.5 4.9 0.1 0.9 0.2 0.4 80.1 2.6 3.2 0.2 0.4 5.3 0.0 0.4 4.1 8.5 8.5 0.0 0.2 0.1 0.9 0.3 6.9 0.8 0.3 0.1 4.3 0.4 0.2 0.3 0.1 0.2 0.2 0.0 0.1 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.1 0.0 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.5 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 2.0 0.1 0.1 0.0 0.1 13.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.6 0.2 0.5 1.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.3 0.3 0.5 0.4 1.1 0.6 0.3 0.9 0.2 0.4 0.3 HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063224-72077246 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "liver: 151.4" "Cell line enriched" "Detected in some" 14 "Hep G2: 32.8" "Cancer enriched" "Detected in some" 53 "liver cancer: 185.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA047750 Supported Approved Vesicles "Secreted to blood" 49000000000 77000000000 Vesicles "HPA047750: " "unprognostic (2.43e-1)" "unprognostic (4.69e-2)" "unprognostic (5.97e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (8.21e-2)" "unprognostic (2.30e-1)" "unprognostic (3.44e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" 0.2 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 15.2 0.7 0.8 0.1 151.4 0.0 0.1 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 2.9 1.1 1.0 0.4 2.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 1.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 1.1 1.3 1.0 0.1 0.5 0.4 0.4 0.3 1.1 2.0 1.1 0.3 0.4 0.3 2.9 2.3 0.3 HPRT1 "HGPRT, HPRT" ENSG00000165704 "Hypoxanthine phosphoribosyltransferase 1" P00492 X 134460153-134520513 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease mutation, FDA approved drug targets, Gout" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006360, CAB012200" Enhanced Supported Cytosol 15000000 Cytosol "CAB012200: AB_297217, HPA006360: AB_1079082" "unprognostic (2.02e-1)" "unprognostic (2.18e-1)" "unprognostic (1.46e-1)" "unprognostic (2.32e-3)" "unprognostic (8.55e-2)" "prognostic unfavourable (1.35e-5)" "unprognostic (1.58e-2)" "unprognostic (4.77e-3)" "unprognostic (4.93e-2)" "unprognostic (2.02e-2)" "unprognostic (7.05e-2)" "unprognostic (1.38e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-1)" "unprognostic (2.04e-1)" "unprognostic (2.70e-2)" "unprognostic (1.51e-1)" 7.9 14.9 31.0 12.6 30.2 25.3 11.3 24.2 49.8 7.5 13.7 5.8 9.8 11.0 7.9 36.2 10.3 9.4 8.1 12.8 27.6 37.3 18.4 24.7 7.3 15.9 23.5 28.9 9.8 20.2 9.9 18.6 8.8 34.4 8.8 13.2 9.7 7.1 9.5 10.7 8.0 14.2 9.5 9.8 8.7 17.1 39.7 4.9 13.7 12.3 8.6 15.9 10.8 7.5 13.5 19.7 10.1 18.5 19.9 29.3 12.6 31.0 15.0 4.2 8.7 9.5 13.7 12.8 16.6 16.0 21.3 28.0 13.4 19.9 35.2 37.9 10.8 19.1 27.4 22.8 36.8 29.2 51.3 19.1 21.3 13.6 9.4 41.0 17.6 10.1 8.6 18.9 30.3 24.5 14.6 0.9 16.6 31.7 31.6 35.6 8.7 40.3 19.0 21.6 36.1 25.6 15.1 26.9 14.7 12.0 9.7 11.3 8.3 17.2 12.1 14.5 10.9 41.4 41.2 13.4 23.2 0.2 17.8 45.6 7.9 2.2 11.6 10.1 11.6 18.5 16.7 12.3 17.3 15.3 19.7 13.5 14.3 15.1 2.9 19.9 17.2 8.2 29.3 12.6 31.0 30.2 24.2 49.8 27.6 37.3 23.5 28.9 34.4 4.9 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 24.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 17.8;neutrophil: 12.8" "Group enriched" "Detected in many" 5 "granulocytes: 12.8;monocytes: 17.8" "Region enhanced" "Detected in some" "olfactory region: 4.5" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" 9700000 Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 4.9 5.1 3.0 6.8 3.5 2.2 1.2 0.8 2.4 3.6 6.2 7.1 0.0 2.3 2.9 2.8 14.5 5.7 3.0 5.8 3.2 1.5 3.0 5.6 8.2 16.1 7.1 1.4 7.5 1.1 15.5 2.3 11.3 3.4 1.1 7.0 0.7 12.5 2.1 0.7 6.9 3.6 2.1 7.0 19.0 2.4 6.0 2.8 1.6 1.4 16.9 9.7 2.4 4.9 0.3 1.9 12.8 17.8 1.4 3.4 4.8 8.1 0.4 0.0 1.1 1.9 0.6 0.0 1.0 4.5 2.0 8.7 0.2 6.1 0.2 1.4 2.2 7.9 10.3 1.4 3.6 0.8 0.9 2.2 5.8 0.1 1.1 1.4 4.9 0.8 3.1 1.4 9.8 10.8 0.0 24.7 0.9 1.7 0.1 0.1 0.4 1.5 0.0 0.3 0.3 5.7 0.2 5.8 0.0 11.3 6.2 0.9 0.8 1.9 12.6 0.9 2.8 0.8 1.0 0.3 3.8 0.1 6.5 6.6 1.5 0.2 17.8 0.0 1.0 6.7 0.7 0.2 1.9 0.7 1.9 0.3 1.4 1.2 12.8 1.4 0.9 0.1 3.4 4.8 3.0 3.5 0.8 2.4 3.2 1.5 7.1 1.4 3.4 2.8 HS3ST1 3OST1 ENSG00000002587 "Heparan sulfate-glucosamine 3-sulfotransferase 1" O14792 4 11393150-11429765 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.4;gallbladder: 31.9;ovary: 30.3" "Cell line enhanced" "Detected in some" "A-431: 4.4;CAPAN-2: 14.0;HaCaT: 4.2;RPTEC TERT1: 12.4;RT4: 10.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "cerebellum: 27.4;cerebral cortex: 9.0" "Group enriched" "Detected in some" 39 "memory B-cell: 7.3;naive B-cell: 15.8;plasmacytoid DC: 22.3" "Group enriched" "Detected in many" 99 "B-cells: 15.8;dendritic cells: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002237 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA002237: AB_1079085" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (4.01e-2)" "prognostic favourable (7.73e-4)" "unprognostic (3.32e-2)" "unprognostic (8.90e-3)" "unprognostic (4.21e-1)" "unprognostic (2.08e-1)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "prognostic favourable (5.99e-8)" "unprognostic (9.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "prognostic favourable (8.67e-4)" 2.3 2.9 1.6 2.8 2.2 2.8 2.0 27.4 9.0 3.3 2.7 1.1 3.6 3.5 4.3 5.0 10.2 4.3 31.9 2.2 1.7 1.8 10.4 0.9 3.4 2.1 1.9 1.5 30.3 1.1 0.7 8.9 1.0 2.4 3.2 1.7 1.7 3.7 2.4 0.7 0.8 2.9 1.7 2.2 3.0 7.0 3.0 0.3 3.8 1.8 7.0 7.4 7.3 2.4 15.8 22.3 0.1 0.1 0.0 0.1 0.6 4.4 0.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 14.0 0.0 0.4 0.0 4.2 0.0 2.5 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.9 1.1 1.0 0.0 0.0 12.4 10.1 3.7 0.0 0.0 0.1 0.5 0.0 0.0 2.0 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.1 7.3 0.0 0.0 0.3 15.8 0.0 0.0 0.0 0.0 0.0 22.3 0.0 0.6 1.6 2.2 27.4 9.0 1.7 1.8 1.9 1.5 2.4 0.3 HS3ST2 3OST2 ENSG00000122254 "Heparan sulfate-glucosamine 3-sulfotransferase 2" Q9Y278 16 22814177-22916338 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 12.7;brain: 38.2;lung: 13.4" "Group enriched" "Detected in some" 5 "HaCaT: 10.2;SH-SY5Y: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017736 Approved "HPA017736: AB_1851095" "unprognostic (4.09e-2)" "unprognostic (2.90e-3)" "unprognostic (5.97e-3)" "unprognostic (3.46e-3)" "prognostic unfavourable (1.57e-4)" "unprognostic (2.00e-1)" "unprognostic (1.05e-1)" "unprognostic (2.17e-3)" "unprognostic (1.83e-1)" "unprognostic (2.75e-2)" "unprognostic (1.95e-1)" "unprognostic (2.45e-1)" "prognostic favourable (1.35e-4)" "unprognostic (4.89e-2)" "unprognostic (1.16e-1)" "unprognostic (1.35e-1)" "unprognostic (3.00e-2)" 12.7 1.7 3.8 1.1 6.5 1.1 2.4 0.5 38.2 2.0 1.4 0.3 0.3 1.0 1.0 1.0 1.2 1.0 1.1 3.8 7.8 4.3 1.0 2.2 13.4 2.1 2.2 8.4 4.5 1.0 1.0 0.4 1.2 1.5 2.0 1.4 5.0 2.9 1.1 1.0 2.0 1.0 1.2 1.0 1.1 1.1 1.1 0.0 0.0 1.8 0.4 1.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 6.5 0.5 19.1 7.8 4.3 2.2 8.4 1.5 0.0 HS3ST3A1 "30ST3A1, 3OST3A1" ENSG00000153976 "Heparan sulfate-glucosamine 3-sulfotransferase 3A1" Q9Y663 17 13495689-13601927 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 16.9;U-251 MG: 46.9;U-87 MG: 29.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basal ganglia: 1.0;cerebral cortex: 2.2;pons and medulla: 3.0" "Cell type enhanced" "Detected in many" "T-reg: 5.1" "Group enriched" "Detected in many" 6 "dendritic cells: 3.9;T-cells: 5.1" "HPA062518, HPA071530" Uncertain Approved Microtubules Microtubules "HPA062518: , HPA071530: " "unprognostic (2.88e-3)" "unprognostic (4.21e-2)" "unprognostic (8.35e-2)" "unprognostic (3.50e-2)" "unprognostic (1.48e-3)" "unprognostic (4.44e-2)" "unprognostic (2.01e-1)" "unprognostic (4.46e-3)" "unprognostic (2.12e-4)" "unprognostic (1.12e-2)" "unprognostic (8.52e-2)" "unprognostic (1.55e-1)" "unprognostic (1.85e-9)" "unprognostic (1.83e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-3)" "unprognostic (4.70e-3)" 1.3 3.3 0.2 2.8 1.0 1.5 2.3 0.1 2.2 7.8 1.6 0.3 5.8 2.3 3.3 1.3 8.1 1.9 1.3 3.8 0.3 0.2 1.7 3.4 2.2 9.3 0.1 0.4 12.1 0.4 0.0 1.2 6.8 3.0 9.9 0.5 2.0 3.3 8.6 0.9 1.1 1.7 0.4 1.3 11.7 1.0 2.9 0.0 0.6 0.6 6.3 12.7 1.4 5.3 0.1 3.9 0.5 0.1 0.7 5.1 0.8 0.0 0.1 1.1 0.0 0.8 2.2 2.0 7.5 1.6 1.2 0.8 0.0 0.2 0.0 1.0 4.1 0.0 0.0 0.0 1.0 0.4 7.7 1.9 0.5 0.7 0.6 0.0 0.5 1.9 0.0 3.3 0.7 0.0 7.4 0.0 1.3 0.9 0.0 1.3 1.4 16.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.0 46.9 0.0 0.0 0.0 29.1 0.0 3.5 0.0 0.0 0.0 1.7 0.0 0.8 0.0 1.2 1.4 0.0 0.1 1.4 1.4 0.5 0.7 0.1 3.9 5.1 0.8 0.2 1.0 0.1 2.2 0.3 0.2 0.1 0.4 3.0 0.0 HS3ST3B1 "30ST3B1, 3OST3B1" ENSG00000125430 "Heparan sulfate-glucosamine 3-sulfotransferase 3B1" Q9Y662 17 14301083-14349404 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 20.6;liver: 29.1;lymphoid tissue: 26.6;placenta: 33.5;salivary gland: 12.6" "Cell line enhanced" "Detected in many" "AF22: 15.2;BEWO: 10.9;Hep G2: 13.2;HSkMC: 15.1;U-251 MG: 13.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.7;pons and medulla: 6.0" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 20.6" "Group enriched" "Detected in many" 5 "dendritic cells: 20.6;T-cells: 14.7" HPA064126 Approved Vesicles Vesicles "HPA064126: " "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-2)" "unprognostic (5.55e-3)" "unprognostic (2.85e-3)" "unprognostic (5.22e-2)" "unprognostic (5.03e-3)" "unprognostic (1.79e-1)" "unprognostic (2.93e-1)" "unprognostic (8.13e-3)" "unprognostic (8.80e-2)" "unprognostic (1.13e-1)" "unprognostic (1.02e-3)" "unprognostic (7.77e-3)" "unprognostic (9.46e-2)" "unprognostic (1.91e-1)" "unprognostic (1.54e-3)" 1.4 1.4 0.6 8.7 0.8 1.3 3.0 0.9 2.7 3.8 1.8 0.0 0.8 1.4 1.0 0.3 2.8 1.7 2.6 2.0 0.6 0.7 3.6 29.1 3.7 26.6 0.6 0.0 4.7 1.3 0.4 1.4 33.5 6.0 2.4 1.9 5.3 12.6 2.5 1.8 2.2 2.5 0.6 2.9 4.9 1.4 0.7 0.0 13.2 1.5 2.5 5.9 1.5 5.3 0.4 20.6 0.5 0.4 3.8 14.7 2.7 0.0 0.3 15.2 0.0 4.6 5.2 10.9 4.3 6.3 3.9 4.1 0.0 0.1 0.0 0.0 5.9 0.0 0.4 2.4 2.0 1.2 3.1 0.3 2.0 13.2 6.0 0.5 2.3 15.1 0.8 1.3 3.6 0.0 4.5 0.0 3.1 0.8 0.7 0.6 0.5 0.4 2.7 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 3.8 0.0 0.0 13.9 0.0 0.0 0.0 3.0 0.0 0.9 0.1 0.2 0.0 6.3 0.4 5.0 0.4 7.6 4.9 0.4 0.4 7.7 7.5 0.5 3.8 0.4 20.6 14.7 2.7 0.6 0.8 0.9 2.7 0.6 0.7 0.6 0.0 6.0 0.0 HS3ST5 3-OST-5 ENSG00000249853 "Heparan sulfate-glucosamine 3-sulfotransferase 5" Q8IZT8 6 114055586-114343045 "Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;seminal vesicle: 9.4;skeletal muscle: 10.1" "Cell line enhanced" "Detected in some" "PC-3: 4.9;RT4: 9.0;SCLC-21H: 17.5;U-266/70: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021823, HPA064677" Approved "HPA021823: AB_1851100, HPA064677: AB_2685318" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-2)" "unprognostic (1.04e-2)" "unprognostic (1.72e-2)" "unprognostic (3.00e-2)" "unprognostic (7.98e-4)" "unprognostic (5.39e-2)" "unprognostic (6.29e-2)" "unprognostic (1.61e-1)" "unprognostic (1.91e-1)" "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.01e-1)" "unprognostic (3.48e-1)" "unprognostic (1.53e-2)" 0.5 1.9 3.3 0.9 13.1 1.3 0.5 0.6 11.9 0.8 1.0 9.1 3.5 0.7 0.8 0.5 0.6 0.6 0.7 0.5 4.2 3.5 0.9 0.5 1.1 0.5 6.1 2.7 0.6 1.3 0.5 0.3 0.6 7.8 0.7 0.9 0.6 0.7 9.4 10.1 1.3 1.2 0.9 7.5 0.5 1.2 0.9 8.0 0.0 0.6 0.0 0.5 2.5 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 4.9 0.0 1.0 0.0 0.0 9.0 17.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.1 4.4 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.3 13.1 0.6 5.7 4.2 3.5 6.1 2.7 7.8 8.0 HSD11B1 "HSD11, HSD11B, SDR26C1" ENSG00000117594 "Hydroxysteroid 11-beta dehydrogenase 1" P28845 1 209686178-209734950 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 183.4" "Cell line enriched" "Detected in some" 5 "ASC diff: 148.3" "Cancer enriched" "Detected in all" 28 "liver cancer: 197.4" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 9.2" "Lineage enriched" "Detected in single" 20 "T-cells: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047729 Enhanced 77000 "HPA047729: " "unprognostic (1.08e-3)" "unprognostic (2.13e-1)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.02e-2)" "unprognostic (1.12e-1)" "unprognostic (1.30e-1)" "unprognostic (3.63e-2)" "unprognostic (8.35e-3)" "unprognostic (8.69e-2)" "prognostic unfavourable (1.97e-10)" "unprognostic (3.41e-2)" "unprognostic (3.91e-2)" "unprognostic (6.45e-2)" "unprognostic (1.59e-2)" 4.6 1.6 1.1 3.0 3.1 0.3 2.4 9.9 3.9 0.6 1.0 1.6 2.7 0.5 0.8 8.7 1.5 0.9 1.9 3.0 1.8 0.9 2.6 183.4 7.2 1.3 8.2 2.0 12.6 0.9 0.3 1.5 26.5 3.3 7.1 0.9 1.5 0.6 3.0 1.5 6.3 0.9 2.7 1.3 3.5 1.4 2.3 2.5 0.0 1.0 0.6 0.6 3.9 1.4 0.2 0.0 0.2 0.1 0.4 9.2 0.8 0.0 0.0 0.0 0.0 148.3 15.4 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.8 0.0 1.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 1.2 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.6 0.2 9.2 2.0 0.0 0.0 0.2 0.0 0.2 0.4 0.0 0.0 2.4 0.8 1.1 3.1 9.9 3.9 1.8 0.9 8.2 2.0 3.3 2.5 HSD17B1 "EDH17B2, EDHB17, HSD17, MGC138140, SDR28C1" ENSG00000108786 "Hydroxysteroid 17-beta dehydrogenase 1" P14061 17 42549214-42555213 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "placenta: 217.6" "Cell line enriched" "Detected in many" 8 "BEWO: 87.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA021032, HPA065296" Enhanced Supported Cytosol Cytosol "HPA021032: AB_1844345, HPA065296: AB_2685457" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (1.68e-2)" "unprognostic (9.25e-2)" "unprognostic (1.73e-1)" "unprognostic (3.88e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (9.35e-2)" "unprognostic (6.04e-2)" "unprognostic (2.88e-5)" "unprognostic (2.17e-1)" "unprognostic (1.30e-1)" "unprognostic (2.60e-2)" "unprognostic (5.09e-1)" "unprognostic (4.98e-1)" "unprognostic (1.32e-2)" 2.8 1.5 2.0 1.7 2.1 1.1 1.8 2.7 3.1 1.3 1.3 1.3 1.3 1.9 1.5 1.3 4.3 1.4 1.3 1.4 2.4 1.4 1.4 1.3 1.3 1.6 2.4 1.3 5.8 2.6 0.2 1.4 217.6 1.3 1.5 0.2 1.3 2.9 1.3 3.5 4.1 1.9 1.3 1.9 2.1 2.0 2.3 1.3 1.3 1.8 1.3 1.3 1.3 1.8 6.0 5.5 7.5 8.6 6.1 5.4 5.5 1.6 1.7 0.9 4.5 0.6 0.1 87.6 1.2 0.0 0.0 0.0 1.0 0.9 0.0 1.1 0.0 2.6 0.1 0.7 0.0 2.4 2.8 1.2 1.1 1.5 0.2 1.0 1.4 0.2 2.5 0.1 0.5 0.0 1.6 0.3 0.0 1.5 1.3 1.1 0.4 0.8 1.3 1.1 0.7 0.1 1.3 1.2 1.8 0.7 8.9 1.4 10.7 0.8 1.4 1.4 1.7 0.9 0.8 2.5 1.4 0.6 0.5 0.9 1.0 3.6 7.6 7.5 4.9 8.6 5.3 5.6 5.4 5.1 5.5 6.0 5.1 4.4 7.2 6.1 5.3 4.3 3.7 5.5 2.0 2.1 2.7 1.5 2.4 1.4 2.4 1.3 1.3 1.3 HSD17B10 "17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1" ENSG00000072506 "Hydroxysteroid 17-beta dehydrogenase 10" Q99714 X 53431258-53434373 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Oxidoreductase "Disease mutation, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001432 Approved 1800000 "HPA001432: AB_1078740" "unprognostic (1.27e-1)" "prognostic favourable (2.80e-4)" "unprognostic (2.60e-1)" "unprognostic (2.15e-1)" "unprognostic (2.10e-1)" "unprognostic (1.30e-1)" "unprognostic (8.37e-2)" "unprognostic (5.24e-2)" "unprognostic (1.02e-1)" "unprognostic (8.64e-3)" "unprognostic (4.08e-3)" "unprognostic (2.04e-1)" "unprognostic (1.95e-2)" "unprognostic (8.38e-2)" "unprognostic (3.07e-3)" "unprognostic (2.92e-1)" "unprognostic (9.51e-2)" 20.9 29.8 13.2 19.1 14.5 16.4 15.9 7.9 14.0 16.9 20.6 16.2 20.2 17.2 17.1 19.0 31.3 14.8 19.6 42.6 11.9 14.0 33.9 96.7 12.7 21.6 16.1 9.7 21.0 32.7 12.5 18.4 25.0 14.9 15.3 19.4 13.0 23.2 17.8 35.4 22.9 17.4 18.6 14.8 19.7 17.4 8.6 14.0 25.6 28.4 39.0 26.0 16.1 17.9 30.4 53.2 12.8 38.2 27.7 33.3 32.9 22.0 37.8 18.5 34.2 18.2 8.0 27.9 13.7 13.7 36.6 24.1 38.8 19.1 37.7 12.5 15.7 23.2 59.4 27.7 20.1 29.9 33.3 17.7 54.2 32.1 30.5 33.5 27.8 17.0 26.4 28.3 15.9 26.7 25.4 29.9 16.9 77.9 29.6 50.3 51.1 48.9 30.3 34.1 66.7 28.1 24.5 32.7 43.1 39.5 47.3 25.0 49.8 31.2 11.9 15.7 25.0 32.7 20.7 24.5 34.1 46.6 21.8 70.5 23.1 12.8 38.2 11.4 27.0 36.7 27.8 30.0 25.1 26.7 53.2 30.4 21.1 22.2 3.2 27.7 26.8 29.0 33.3 32.9 13.2 14.5 7.9 14.0 11.9 14.0 16.1 9.7 14.9 14.0 HSD17B11 "17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2" ENSG00000198189 "Hydroxysteroid 17-beta dehydrogenase 11" Q8NBQ5 4 87336610-87391386 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 100.1;intestine: 81.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 100.1" "Group enriched" "Detected in all" 4 "granulocytes: 100.1;monocytes: 25.8" "Low region specificity" "Detected in all" HPA021608 Enhanced Supported "Lipid droplets" "Intracellular and membrane" 14000 "Lipid droplets" "HPA021608: AB_1847660" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.14e-2)" "unprognostic (9.68e-2)" "unprognostic (1.92e-1)" "unprognostic (3.35e-1)" "unprognostic (3.70e-2)" "unprognostic (1.78e-1)" "unprognostic (8.53e-2)" "unprognostic (1.24e-3)" "unprognostic (1.83e-1)" "unprognostic (2.65e-3)" "unprognostic (5.53e-2)" "unprognostic (2.13e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-2)" 22.0 23.8 11.1 15.5 8.4 23.6 18.9 23.8 12.8 19.6 58.3 7.2 9.5 53.0 19.1 15.7 6.5 14.6 26.3 9.0 10.1 6.4 18.1 57.4 25.3 14.7 14.2 7.9 18.0 24.5 3.0 12.6 11.4 9.7 15.5 36.2 5.7 6.7 9.0 6.4 6.2 81.3 15.2 14.2 12.2 11.6 11.6 10.6 15.8 8.1 8.4 8.2 21.0 15.9 7.7 14.2 100.1 25.8 10.4 10.3 18.7 0.2 10.6 5.2 13.0 16.0 22.1 7.4 5.7 9.1 3.8 7.0 8.8 68.2 0.0 11.2 5.9 0.2 15.1 1.2 4.2 16.8 3.2 14.7 5.9 29.8 9.1 26.1 27.3 15.6 0.4 5.2 1.8 7.3 15.2 7.6 6.9 0.4 5.3 32.0 8.9 1.7 14.6 4.8 17.2 10.5 16.3 1.7 16.7 11.3 0.3 19.4 0.0 25.5 6.1 2.6 11.7 10.4 2.9 3.7 1.5 1.6 4.8 18.5 17.7 61.0 25.8 55.9 8.7 18.4 10.3 7.7 8.8 9.0 14.2 6.6 8.1 9.0 100.1 10.4 15.2 4.8 9.9 18.7 11.1 8.4 23.8 12.8 10.1 6.4 14.2 7.9 9.7 10.6 HSD17B12 "KAR, SDR12C1" ENSG00000149084 "Hydroxysteroid 17-beta dehydrogenase 12" Q53GQ0 11 43680558-43856617 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016427 Approved 200000 "HPA016427: AB_1844347" "unprognostic (1.93e-1)" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-3)" "prognostic unfavourable (2.76e-4)" "unprognostic (2.99e-1)" "unprognostic (3.31e-2)" "unprognostic (9.16e-3)" "unprognostic (5.16e-2)" "unprognostic (7.54e-2)" "prognostic favourable (2.10e-8)" "unprognostic (6.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" 27.2 32.6 33.5 16.6 31.9 10.5 30.4 12.8 33.1 26.3 30.7 31.4 29.3 32.0 22.3 25.3 24.3 20.1 28.0 36.9 30.9 31.1 42.9 59.8 25.8 19.9 38.5 21.4 22.4 26.4 66.6 29.4 19.4 45.7 26.4 29.4 26.6 25.3 22.9 16.1 18.2 30.8 23.3 44.9 23.5 25.6 17.6 24.4 15.2 32.4 32.5 17.5 19.4 18.6 12.8 18.7 9.8 12.7 13.5 15.0 9.6 8.9 14.5 16.2 16.4 54.4 51.7 10.6 22.9 22.6 16.0 17.5 17.6 18.7 22.3 16.3 20.6 35.0 11.2 28.9 19.8 4.1 20.9 10.3 8.2 15.3 27.6 31.9 29.5 31.7 22.3 16.1 46.0 22.1 9.7 37.2 13.8 5.1 8.4 14.2 29.6 10.6 14.4 24.0 25.2 30.5 22.0 5.9 13.3 30.8 26.0 22.4 18.6 25.8 21.2 17.3 6.8 44.9 26.8 19.2 24.1 13.3 18.8 5.7 13.0 6.1 12.2 5.5 11.0 12.7 11.7 11.0 8.8 9.2 18.7 12.8 15.0 12.9 9.8 13.5 6.5 15.1 5.0 9.6 33.5 31.9 12.8 30.8 30.9 31.1 38.5 21.4 45.7 24.4 HSD17B2 "HSD17, SDR9C2" ENSG00000086696 "Hydroxysteroid 17-beta dehydrogenase 2" P37059 16 82035004-82098534 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 83.1;liver: 52.9;placenta: 110.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 23.7;Hep G2: 18.8;hTERT-HME1: 11.3;RT4: 38.9;TIME: 21.8" "Cancer enhanced" "Detected in many" "liver cancer: 10.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "midbrain: 2.6;pons and medulla: 3.5" "Not detected" "Not detected" "HPA021826, HPA050235" Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA021826: AB_10961148, HPA050235: " "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.48e-2)" "unprognostic (2.58e-1)" "unprognostic (1.77e-1)" "unprognostic (4.29e-2)" "unprognostic (2.60e-1)" "unprognostic (7.35e-2)" "unprognostic (6.05e-3)" "unprognostic (4.98e-2)" "unprognostic (7.35e-2)" "unprognostic (6.31e-4)" "unprognostic (5.39e-2)" "unprognostic (1.14e-1)" "unprognostic (4.30e-2)" "prognostic favourable (3.83e-4)" 0.7 0.1 0.2 4.1 0.2 0.0 3.9 0.2 0.3 0.7 41.3 0.3 0.2 71.3 0.6 0.2 1.7 0.2 13.3 0.2 0.2 0.2 2.8 52.9 1.0 0.2 0.2 0.2 0.2 16.0 0.0 0.6 110.8 0.4 3.1 9.4 21.3 9.4 0.2 0.3 1.8 83.1 1.5 0.2 0.2 3.2 0.2 0.2 0.2 0.2 1.1 1.3 21.4 6.6 1.3 1.4 3.6 1.1 1.0 0.7 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.3 0.0 23.7 0.0 0.0 4.3 0.7 0.0 4.7 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.1 0.1 18.8 0.1 0.1 0.1 0.0 1.2 0.0 11.3 0.3 0.0 0.2 3.5 0.1 0.0 0.4 0.1 8.6 0.0 0.0 0.5 0.4 38.9 0.2 0.6 0.0 1.1 0.1 0.0 0.0 21.8 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.0 1.6 1.1 0.6 0.7 0.5 0.4 0.6 0.4 0.4 0.3 1.3 0.4 0.6 3.6 1.0 0.6 1.4 0.3 0.1 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.2 0.4 0.2 HSD17B3 SDR12C2 ENSG00000130948 "Hydroxysteroid 17-beta dehydrogenase 3" P37058 9 96235306-96302152 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Disease mutation, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 41.9" "Group enriched" "Detected in some" 5 "HBEC3-KT: 4.9;HEL: 4.3;U-2 OS: 8.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056833 Enhanced Supported Vesicles Vesicles "HPA056833: " "unprognostic (2.78e-1)" "unprognostic (6.61e-3)" "unprognostic (1.03e-1)" "unprognostic (5.76e-2)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (3.08e-2)" "unprognostic (6.15e-2)" "unprognostic (1.74e-1)" "unprognostic (5.13e-2)" "unprognostic (3.26e-4)" "unprognostic (3.45e-1)" "unprognostic (5.48e-8)" "unprognostic (8.47e-3)" "unprognostic (1.15e-1)" "unprognostic (7.24e-2)" "unprognostic (3.11e-2)" 0.5 0.4 1.0 0.5 1.0 0.4 0.5 0.5 0.9 0.8 0.5 0.5 0.5 0.4 0.5 0.5 0.5 1.3 0.5 0.5 1.7 0.5 1.0 6.3 0.5 0.5 1.6 0.5 0.5 1.3 0.4 0.5 0.5 0.5 0.8 0.4 0.5 0.5 0.5 0.5 0.5 1.1 0.5 1.9 0.5 0.4 41.9 0.5 0.5 4.5 0.5 0.5 0.5 0.5 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.0 1.0 0.5 0.9 1.7 0.5 1.6 0.5 0.5 0.5 HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452443-119637199 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes 6900000 Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favourable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favourable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" 25.1 42.4 22.1 15.5 21.3 6.4 46.0 12.3 23.6 27.8 30.1 24.1 83.8 28.6 16.2 20.7 24.6 15.1 20.6 27.3 23.8 21.2 31.3 116.3 30.5 16.7 27.0 21.7 15.1 29.9 33.2 20.5 19.0 23.9 20.9 25.2 10.7 20.0 86.2 20.7 19.2 30.5 15.6 33.6 16.9 20.7 8.1 25.5 10.8 48.9 17.3 14.5 24.1 25.3 6.1 11.1 31.4 13.6 3.2 4.2 5.3 17.7 15.3 28.8 38.1 71.9 33.8 15.2 17.3 23.3 16.4 29.9 12.6 29.5 23.7 35.6 18.7 17.8 21.1 37.6 25.6 25.9 19.5 31.2 16.6 24.1 18.3 9.8 48.9 29.4 15.8 17.6 16.5 28.0 10.6 13.8 17.8 15.4 15.0 6.4 21.3 10.8 19.2 28.8 25.6 26.2 49.0 21.7 18.7 40.6 6.4 18.9 23.6 16.6 19.9 16.1 11.0 17.7 14.1 7.0 14.7 8.7 18.3 26.3 15.8 31.4 13.6 24.7 3.4 8.0 4.2 6.1 3.2 2.9 11.1 5.8 3.1 2.9 2.4 3.2 7.8 6.9 2.0 5.3 22.1 21.3 12.3 23.6 23.8 21.2 27.0 21.7 23.9 25.5 HSD17B6 "HSE, RODH, SDR9C6" ENSG00000025423 "Hydroxysteroid 17-beta dehydrogenase 6" O14756 12 56752161-56787790 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 241.2" "Cell line enhanced" "Detected in many" "Karpas-707: 11.7;U-266/84: 14.6" "Cancer enriched" "Detected in many" 5 "liver cancer: 170.3" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059141 Enhanced Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA059141: " "unprognostic (7.70e-2)" "unprognostic (8.76e-2)" "unprognostic (5.08e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-2)" "prognostic favourable (6.32e-4)" "unprognostic (1.06e-2)" "unprognostic (3.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (2.50e-10)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" 1.1 0.5 3.6 1.4 5.2 0.2 0.3 1.2 2.4 9.4 3.3 0.5 2.6 0.6 4.1 0.7 1.6 0.9 2.6 0.4 1.6 1.4 0.5 241.2 8.7 0.3 2.0 2.6 1.1 0.3 0.2 0.0 0.9 0.6 7.9 1.3 1.4 0.2 10.2 0.2 0.2 0.7 11.3 1.0 6.2 0.8 3.2 0.8 0.0 13.3 0.0 0.3 9.9 2.3 2.0 2.0 0.1 1.3 0.1 3.4 0.8 0.3 0.7 1.6 0.3 1.7 1.2 2.0 3.6 3.1 1.7 1.7 0.4 0.4 10.2 1.5 0.4 0.3 5.3 0.9 1.0 6.5 2.0 3.2 1.0 0.5 1.1 1.6 5.3 0.9 0.3 1.0 0.5 0.0 0.9 11.7 0.8 2.1 4.6 1.0 6.6 0.6 6.3 0.7 2.5 0.2 1.2 9.7 2.0 1.7 3.1 0.8 0.5 1.3 0.3 0.8 0.8 3.6 0.9 10.3 14.6 6.7 1.2 5.8 0.6 0.0 0.2 0.1 3.0 0.6 3.4 2.0 2.5 2.4 0.6 1.1 3.3 2.2 0.0 0.1 1.3 2.0 2.8 0.8 3.6 5.2 1.2 2.4 1.6 1.4 2.0 2.6 0.6 0.8 HSD17B7 "PRAP, SDR37C1" ENSG00000132196 "Hydroxysteroid 17-beta dehydrogenase 7" P56937 1 162790702-162812817 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 16.3;liver: 16.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047496 Approved "HPA047496: " "unprognostic (2.93e-1)" "unprognostic (1.36e-2)" "unprognostic (6.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (2.57e-1)" "unprognostic (2.51e-2)" "unprognostic (1.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.94e-1)" "unprognostic (1.37e-1)" "prognostic unfavourable (8.47e-5)" "unprognostic (6.25e-2)" "unprognostic (1.90e-1)" "unprognostic (6.35e-2)" "unprognostic (3.17e-2)" 1.9 9.2 1.4 2.0 1.0 0.7 4.3 1.4 1.9 2.8 2.9 3.1 2.1 4.4 4.7 2.2 1.6 1.6 1.9 2.6 2.2 16.8 4.3 3.7 1.5 3.6 2.6 2.5 4.1 1.8 2.8 4.0 3.1 1.3 2.0 3.6 3.1 1.8 3.2 2.9 2.9 0.6 2.8 3.9 2.2 2.8 12.5 9.6 15.8 7.4 7.0 16.3 10.5 6.8 7.0 18.5 8.2 10.7 11.5 12.1 2.7 8.9 5.4 10.8 9.6 22.0 16.4 6.3 2.3 11.0 16.8 23.7 5.7 7.1 9.0 4.1 5.3 15.1 8.9 7.3 7.3 6.9 13.2 21.0 6.9 8.9 7.8 11.3 4.6 4.8 9.5 7.9 11.7 8.7 5.3 11.1 10.5 19.2 10.9 15.8 8.2 4.4 4.3 4.2 7.0 9.4 5.3 2.5 5.9 3.8 5.3 6.9 6.8 16.2 4.0 0.6 6.1 15.8 6.0 11.2 13.9 6.1 14.6 12.5 10.5 13.4 6.5 10.9 13.0 13.1 5.0 7.0 7.4 9.6 16.3 10.5 HSD17B8 "D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1" ENSG00000204228 "Hydroxysteroid 17-beta dehydrogenase 8" Q92506 6 33204642-33206831 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 47.8" "Cell line enhanced" "Detected in many" "RPMI-8226: 14.5;T-47d: 9.4;U-266/70: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042132 Enhanced 52000 "HPA042132: AB_10793978" "prognostic favourable (9.99e-4)" "unprognostic (4.24e-1)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (2.10e-1)" "unprognostic (8.11e-2)" "prognostic favourable (1.90e-5)" "unprognostic (1.50e-3)" "unprognostic (3.12e-1)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" "prognostic favourable (2.18e-12)" "unprognostic (2.82e-2)" "unprognostic (5.57e-1)" "unprognostic (3.09e-1)" "unprognostic (3.23e-2)" 3.5 11.5 4.1 5.4 4.1 3.0 6.1 3.4 5.9 5.3 12.4 5.3 17.7 6.6 3.2 14.7 11.3 8.1 8.6 11.0 4.1 3.7 13.9 24.0 8.1 7.7 5.3 4.6 3.3 47.8 12.8 6.6 3.5 4.7 4.5 5.6 9.3 16.7 30.1 14.6 10.6 11.2 4.1 5.3 5.4 5.8 5.1 2.4 10.3 11.2 15.5 10.7 5.3 5.2 4.8 4.8 0.4 3.1 4.1 7.8 6.0 1.1 2.1 0.9 1.3 0.3 0.6 0.3 0.1 0.6 0.0 0.0 1.5 2.5 6.9 1.9 0.1 4.1 1.0 3.2 0.1 1.1 1.2 0.3 2.0 3.7 3.0 0.0 0.5 0.7 4.2 0.0 7.3 0.3 0.1 6.7 0.5 2.3 5.1 0.1 0.3 0.9 3.0 0.1 14.5 4.0 0.1 2.0 1.1 0.4 5.5 1.3 9.4 0.2 0.1 0.2 1.2 0.0 0.0 14.3 6.9 2.5 0.4 0.1 0.2 0.0 1.4 0.4 4.8 3.1 7.8 4.8 7.2 7.3 2.8 3.1 7.6 7.8 0.1 4.1 3.1 4.8 5.2 6.0 4.1 4.1 3.4 5.9 4.1 3.7 5.3 4.6 4.7 2.4 HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "placenta: 231.4" "Cell line enriched" "Detected in some" 9 "CACO-2: 37.0" "Cancer enhanced" "Detected in single" "urothelial cancer: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: , HPA043264: , HPA044028: " "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favourable (4.59e-5)" 0.1 0.6 0.0 0.0 0.3 0.0 0.7 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 231.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.5 11.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 4.1 0.4 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "adrenal gland: 223.2" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.4;SK-MEL-30: 5.1;TIME: 1.2;WM-115: 3.2" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Region enriched" "Detected in single" 198 "basal ganglia: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043261, HPA043264, HPA044028" Supported Uncertain "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: , HPA043264: , HPA044028: " "unprognostic (3.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.80e-1)" "unprognostic (2.72e-2)" "unprognostic (8.87e-2)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (1.94e-1)" "unprognostic (6.51e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" 0.0 223.2 0.0 0.8 19.8 0.0 0.0 0.0 0.0 0.0 0.5 43.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 3.6 0.2 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 1.5 1.4 0.0 0.0 5.1 0.0 0.0 1.2 0.2 0.1 0.1 0.7 0.0 0.0 0.0 0.8 0.0 3.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989152 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis Oxidoreductase "Disease mutation, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.1" "Cell line enhanced" "Detected in many" "HDLM-2: 31.0;Hep G2: 22.7;HMC-1: 35.2;U-2197: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "basophil: 24.5;eosinophil: 13.5" "Lineage enriched" "Detected in single" 29 "granulocytes: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050521, HPA060847" Uncertain Enhanced "Lipid droplets" "Lipid droplets" "HPA050521: , HPA060847: " "unprognostic (5.41e-3)" "unprognostic (4.14e-3)" "prognostic unfavourable (5.95e-4)" "unprognostic (2.62e-2)" "unprognostic (5.06e-3)" "unprognostic (1.47e-2)" "unprognostic (3.52e-2)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.20e-2)" "unprognostic (2.81e-1)" "prognostic unfavourable (1.60e-6)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.79e-1)" 21.6 11.2 2.5 7.5 4.7 1.8 7.3 2.7 4.0 4.9 8.3 4.6 2.8 11.2 5.3 6.4 9.4 4.4 7.4 5.2 3.1 1.6 25.6 74.1 6.4 5.6 3.5 1.4 9.3 17.7 5.6 2.6 6.1 3.7 5.9 3.2 2.9 4.5 2.6 5.1 7.8 13.3 6.7 4.8 8.3 4.8 3.6 3.7 1.0 2.9 4.5 4.6 8.0 3.9 0.1 0.8 24.5 0.8 0.2 0.0 0.3 6.9 8.0 0.8 4.0 2.9 10.5 0.5 8.7 13.7 1.7 3.6 0.5 12.1 0.4 2.9 10.6 2.1 0.7 1.2 0.9 31.0 1.9 0.5 6.3 22.7 2.7 0.1 35.2 5.0 2.1 8.3 1.6 0.7 1.6 0.3 6.5 14.8 0.2 4.9 0.6 1.1 0.8 2.8 7.6 5.3 0.4 3.0 1.5 1.1 5.6 0.7 11.0 0.5 4.0 3.6 1.0 34.3 0.9 0.6 5.0 0.4 14.0 0.8 0.3 24.5 0.8 13.5 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.6 0.2 0.0 0.3 0.0 0.3 2.5 4.7 2.7 4.0 3.1 1.6 3.5 1.4 3.7 3.7 HSPA5 "BiP, GRP78" ENSG00000044574 "Heat shock protein family A (Hsp70) member 5" P11021 9 125234853-125241330 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 200.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005221, HPA038845, HPA038846" Enhanced Approved Cytosol "Intracellular and membrane" 1000000000 Cytosol "CAB005221: AB_631616, HPA038845: AB_10673477, HPA038846: AB_10673478" "unprognostic (3.98e-2)" "unprognostic (2.50e-3)" "unprognostic (6.64e-2)" "unprognostic (9.60e-3)" "unprognostic (1.54e-3)" "unprognostic (6.02e-3)" "unprognostic (9.08e-3)" "unprognostic (9.11e-3)" "unprognostic (4.50e-2)" "unprognostic (7.45e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "prognostic unfavourable (3.05e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (7.28e-2)" "unprognostic (3.66e-2)" 44.2 40.3 26.3 40.8 38.4 125.0 58.8 19.5 26.9 37.7 29.3 19.8 47.0 25.5 31.6 75.3 34.1 31.1 25.5 72.7 23.3 28.6 60.4 147.6 43.6 32.7 34.3 14.3 36.2 110.3 41.1 47.6 62.6 43.5 34.3 33.0 16.5 84.9 40.7 23.9 32.3 38.3 33.8 28.2 33.8 35.1 33.0 41.5 23.2 219.3 21.7 29.8 50.4 75.1 33.3 53.8 57.4 55.3 51.9 63.0 90.0 35.5 24.1 31.7 41.9 38.0 43.9 74.7 64.1 50.9 47.7 56.0 37.2 71.2 41.1 40.1 46.8 45.5 28.3 57.3 51.3 23.8 14.3 24.6 30.1 67.2 200.7 33.5 46.6 27.0 112.5 38.3 167.9 74.1 18.2 57.5 34.7 26.3 14.8 23.7 35.8 24.2 14.0 32.3 66.7 46.2 23.6 16.4 29.2 40.8 43.7 65.4 45.0 24.5 49.7 29.1 28.4 29.7 29.8 60.2 57.5 34.8 70.7 28.3 43.8 57.4 55.3 44.3 61.9 54.8 63.0 33.3 45.7 57.7 48.6 24.9 37.6 46.6 44.3 51.9 35.5 53.8 31.2 90.0 26.3 38.4 19.5 26.9 23.3 28.6 34.3 14.3 43.5 41.5 HSPD1 "GroEL, HSP60, SPG13" ENSG00000144381 "Heat shock protein family D (Hsp60) member 1" P10809 2 197486581-197516737 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, Isomerase" "Cancer-related genes, Disease mutation, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 162.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA001523, CAB002775, HPA050025, CAB072816" Supported Enhanced Mitochondria 53000000 Mitochondria "CAB002775: , CAB072816: , HPA001523: AB_1079028, HPA050025: AB_2680995" "unprognostic (2.79e-2)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "prognostic unfavourable (1.61e-4)" "unprognostic (2.59e-1)" "unprognostic (3.57e-3)" "prognostic unfavourable (2.25e-4)" "unprognostic (3.51e-2)" "unprognostic (9.91e-2)" "unprognostic (8.63e-3)" "unprognostic (3.47e-2)" "unprognostic (7.83e-3)" "unprognostic (5.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (4.10e-2)" 28.5 125.2 28.7 23.4 31.8 21.0 55.9 18.2 24.3 17.4 30.3 17.8 23.3 28.9 17.5 18.5 27.2 25.3 16.3 24.0 24.2 27.8 67.1 147.5 22.4 25.3 35.5 16.1 30.2 50.6 32.5 25.9 27.1 33.6 25.9 37.2 11.9 17.6 21.0 36.4 13.7 32.0 23.6 32.4 22.7 25.2 10.9 35.8 22.7 38.7 29.4 30.3 33.3 162.6 25.6 30.3 6.2 29.3 23.1 33.5 22.2 40.4 49.8 41.8 37.5 28.7 30.0 60.8 42.2 22.3 50.8 37.3 167.0 24.4 123.1 55.1 22.0 41.4 163.6 46.5 72.1 30.2 65.6 87.4 80.6 193.3 27.0 96.8 27.5 33.9 54.0 45.0 79.4 39.8 107.6 48.3 37.3 51.8 60.1 98.0 82.6 104.2 72.3 51.6 88.9 53.4 42.3 54.8 31.0 42.3 45.8 54.1 31.7 57.5 17.7 31.6 43.8 40.6 66.6 27.1 59.6 102.2 37.1 58.5 33.9 4.5 19.7 5.3 15.5 29.3 28.8 25.6 25.0 21.8 30.3 21.0 33.5 29.0 6.2 23.1 25.8 20.2 19.7 22.2 28.7 31.8 18.2 24.3 24.2 27.8 35.5 16.1 33.6 35.8 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122461525-122514908 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 198.9;ASC TERT1: 73.9;fHDF/TERT166: 67.4;HSkMC: 129.7;LHCN-M2: 98.6;U-87 MG: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 2.4;memory CD4 T-cell: 1.6" "Group enriched" "Detected in many" 20 "monocytes: 2.4;T-cells: 1.6" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" 24800000 2600000 "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavourable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavourable (5.62e-6)" 40.8 21.8 64.5 9.1 79.0 0.5 48.2 16.2 62.8 50.4 19.3 60.8 7.2 5.6 47.6 67.0 15.6 19.5 78.7 28.7 50.8 35.4 34.7 60.4 14.6 9.1 62.7 32.5 111.3 14.5 37.6 26.9 114.1 41.9 19.5 14.0 20.7 19.3 31.5 7.5 29.6 9.3 40.5 46.5 10.5 12.9 9.8 49.5 1.7 13.3 8.5 7.1 41.5 27.3 0.0 0.0 0.0 2.4 0.0 1.6 0.7 0.0 3.4 1.5 0.4 198.9 73.9 0.0 8.5 15.6 3.5 1.9 0.0 0.0 0.0 2.3 67.4 1.0 0.6 9.7 0.5 0.0 0.3 0.0 5.7 0.0 10.1 0.0 0.0 129.7 35.7 2.0 16.6 16.3 0.0 0.1 98.6 1.7 0.0 0.0 1.6 5.4 0.0 0.1 0.0 22.5 0.1 0.1 0.3 21.4 0.0 9.2 0.6 0.0 10.7 25.1 0.3 11.3 7.2 0.0 0.0 0.0 81.4 0.0 11.7 0.0 2.4 0.0 0.6 0.0 0.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 64.5 79.0 16.2 54.6 50.8 35.4 62.7 32.5 41.9 49.5 HTRA2 "OMI, PARK13, PRSS25" ENSG00000115317 "HtrA serine peptidase 2" O43464 2 74529377-74533348 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Apoptosis "Hydrolase, Protease, Serine protease" "Disease mutation, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004004, HPA006602, HPA027366" Uncertain Supported Mitochondria Mitochondria "CAB004004: AB_326421, HPA006602: , HPA027366: AB_1851301" "unprognostic (3.09e-1)" "unprognostic (4.06e-2)" "unprognostic (2.82e-1)" "unprognostic (2.58e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavourable (7.77e-8)" "unprognostic (2.12e-3)" "unprognostic (4.18e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-2)" "unprognostic (8.15e-2)" "unprognostic (7.23e-3)" "unprognostic (4.03e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-2)" 16.4 12.7 10.6 14.9 11.3 18.9 12.9 10.7 17.7 12.3 12.8 12.6 9.7 12.6 12.9 6.9 10.7 10.6 9.0 12.9 11.6 8.7 13.1 11.4 11.3 13.2 10.8 11.9 18.7 12.9 10.5 9.0 10.4 13.5 11.6 5.5 10.2 13.1 9.2 17.6 9.0 12.6 11.8 9.1 17.3 11.8 13.9 12.6 12.2 16.8 12.6 9.3 10.4 15.2 12.9 9.4 5.9 8.1 5.5 7.8 7.0 7.9 4.9 5.7 4.9 7.9 3.2 15.2 6.9 3.6 4.2 2.4 9.1 3.5 7.2 5.4 3.9 9.0 6.7 7.9 1.1 16.2 13.4 14.4 4.7 8.0 7.4 6.7 10.6 3.8 5.3 7.9 6.7 5.2 18.9 10.7 3.1 5.2 12.4 14.2 4.7 14.2 8.5 16.1 7.9 3.4 3.2 6.6 7.9 3.7 8.5 13.2 3.9 6.6 3.7 7.3 9.0 14.7 15.4 13.1 4.3 4.7 6.3 10.7 5.8 5.9 8.1 4.8 7.3 6.2 7.8 12.9 7.3 6.2 9.4 11.6 6.3 6.4 3.2 5.5 4.7 6.6 7.4 7.0 10.6 11.3 10.7 17.7 11.6 8.7 10.8 11.9 13.5 12.6 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269765-8307111 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.9" "Cell line enriched" "Detected in some" 5 "U-2197: 62.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 9 "basal ganglia: 8.2" "Cell type enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in female reproductive system" Vesicles "HPA021187: AB_1851311, HPA063810: " "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavourable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavourable (1.29e-4)" "unprognostic (1.34e-2)" 23.7 1.8 0.6 7.3 8.2 5.3 35.6 0.7 0.9 12.3 9.4 0.8 5.4 3.7 19.6 26.6 14.4 7.9 19.8 57.9 0.7 0.3 1.7 1.6 15.4 4.3 0.8 0.9 30.7 2.8 0.0 5.1 9.6 0.9 15.4 2.0 8.6 6.6 3.0 12.9 9.0 6.7 50.1 0.8 1.8 6.8 7.2 0.6 1.3 9.3 11.6 3.0 28.7 12.7 0.0 0.4 1.3 0.3 0.0 0.0 0.1 0.0 0.3 0.4 0.0 2.0 3.8 0.1 0.8 0.0 0.9 0.2 0.0 0.0 0.0 4.7 2.1 0.0 0.4 0.0 0.3 0.0 0.7 0.4 4.9 0.0 2.1 0.0 0.2 0.4 0.0 1.4 0.0 3.3 0.1 0.0 3.5 0.0 0.0 12.0 2.1 0.1 0.1 0.0 0.0 0.0 0.0 5.5 0.1 8.9 0.1 0.0 0.0 0.3 2.7 0.5 1.6 62.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.1 0.6 8.2 0.7 0.9 0.7 0.3 0.8 0.9 0.9 0.6 HTRA4 FLJ90724 ENSG00000169495 "HtrA serine peptidase 4" P83105 8 38974164-38988662 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "placenta: 55.2" "Cell line enriched" "Detected in single" 134 "BEWO: 71.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enhanced" "Detected in some" "hippocampal formation: 2.3" "Low region specificity" "Detected in all" HPA045402 Enhanced "Secreted in female reproductive system" "HPA045402: " "unprognostic (1.20e-1)" "unprognostic (5.83e-4)" "unprognostic (8.02e-2)" "unprognostic (2.13e-2)" "unprognostic (8.20e-2)" "unprognostic (2.42e-2)" "unprognostic (1.80e-1)" "unprognostic (7.40e-3)" "unprognostic (1.40e-1)" "unprognostic (5.14e-4)" "unprognostic (1.01e-1)" "unprognostic (8.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.58e-1)" "unprognostic (5.19e-3)" "unprognostic (2.39e-3)" "unprognostic (1.19e-3)" 2.6 1.1 0.2 0.3 0.2 3.4 0.9 0.2 0.4 1.2 0.5 0.2 1.9 0.0 2.3 0.5 0.5 0.1 0.2 0.2 0.2 0.0 0.2 0.2 4.3 1.0 0.2 0.2 0.4 0.3 0.4 0.5 55.2 0.4 0.5 0.3 1.8 0.8 0.5 0.6 0.4 0.6 0.3 1.8 2.5 0.1 0.4 0.2 0.2 0.6 0.2 0.8 0.5 0.9 3.1 2.2 2.5 1.0 1.0 1.7 0.0 0.1 0.1 0.1 0.1 0.3 0.2 71.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.3 0.1 0.1 0.5 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.3 0.1 1.5 0.8 2.3 1.4 0.7 1.7 1.5 1.3 1.2 0.6 3.1 1.3 1.4 2.5 1.0 1.0 2.2 1.4 0.0 0.2 0.2 0.2 0.4 0.2 0.0 0.2 0.2 0.4 0.2 HUNK ENSG00000142149 "Hormonally up-regulated Neu-associated kinase" P57058 21 31873315-32044633 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 10.4;BEWO: 12.9;RH-30: 14.2;SCLC-21H: 11.6;SiHa: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027295, HPA027372" Approved Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA027295: , HPA027372: " "unprognostic (9.09e-3)" "unprognostic (7.29e-2)" "unprognostic (1.42e-1)" "unprognostic (5.95e-3)" "unprognostic (1.99e-1)" "unprognostic (2.12e-4)" "unprognostic (4.00e-2)" "unprognostic (6.90e-2)" "unprognostic (5.07e-1)" "unprognostic (2.27e-1)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "prognostic favourable (7.48e-5)" "unprognostic (8.84e-2)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.69e-2)" 1.7 1.9 2.7 2.9 3.5 0.5 2.1 3.2 6.4 1.1 5.9 0.2 12.6 2.4 9.0 3.4 1.1 3.3 1.0 1.7 3.7 3.2 6.0 1.3 1.7 0.7 1.2 2.1 1.8 15.7 0.2 4.7 7.6 1.4 4.0 6.5 9.1 1.5 11.1 0.6 5.0 4.4 4.1 0.9 0.4 2.1 1.8 0.2 0.4 1.1 2.2 1.0 3.8 7.7 1.0 0.7 1.7 0.5 0.5 0.5 0.1 0.0 3.0 10.4 0.1 0.0 0.0 12.9 1.0 0.0 0.2 0.0 4.1 0.1 0.0 0.4 4.8 0.0 6.2 0.0 0.0 0.0 3.1 0.0 2.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.9 7.9 0.1 0.1 14.2 0.0 1.1 0.0 11.6 7.7 10.2 0.8 0.4 4.2 1.1 0.0 0.0 7.4 0.0 0.0 0.1 0.0 1.4 0.0 0.0 4.9 0.8 0.5 0.5 0.5 0.3 0.3 0.5 0.5 0.3 0.2 1.0 0.5 0.5 1.7 0.5 0.3 0.7 0.4 0.1 2.7 3.5 3.2 6.4 3.7 3.2 1.2 2.1 1.4 0.2 HUWE1 "Ib772, KIAA0312, UREB1" ENSG00000086758 "HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase" Q7Z6Z7 X 53532096-53686729 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002548, CAB022718" Approved Enhanced Nucleoplasm,Cytosol 3400 "Nucleoplasm, Cytosol" "CAB022718: , HPA002548: AB_1080489" "unprognostic (4.73e-2)" "unprognostic (9.06e-2)" "unprognostic (1.31e-1)" "unprognostic (1.59e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-2)" "unprognostic (1.33e-2)" "unprognostic (2.21e-1)" "unprognostic (3.56e-1)" "unprognostic (5.51e-2)" "unprognostic (1.33e-1)" "unprognostic (8.89e-2)" "unprognostic (8.10e-3)" "unprognostic (2.17e-1)" "unprognostic (1.32e-1)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" 24.6 28.2 27.7 23.8 43.3 22.4 28.0 37.0 41.1 31.8 25.9 34.3 26.6 17.1 31.9 52.4 27.4 26.5 23.1 27.1 28.0 31.8 30.3 26.2 20.3 23.1 30.0 30.2 43.3 27.8 59.8 34.2 27.2 34.6 27.3 22.7 25.6 26.4 29.6 59.1 50.1 22.1 33.9 23.9 26.6 25.7 28.4 27.7 32.4 27.6 20.7 28.6 27.0 22.9 5.1 7.2 8.2 7.0 6.9 8.9 3.5 50.1 30.9 20.1 14.2 35.3 21.1 24.8 15.1 19.5 15.9 16.7 23.5 16.2 26.3 10.3 27.4 24.1 45.4 25.3 21.8 37.9 20.1 20.9 27.7 18.3 32.5 31.3 12.9 20.1 19.0 38.2 43.9 27.5 20.8 17.1 20.6 30.9 16.9 17.5 27.5 22.3 15.7 27.8 15.9 26.4 34.8 16.8 12.1 42.6 19.0 13.6 27.2 15.2 35.0 14.7 21.1 20.9 19.2 15.0 14.7 23.0 15.7 30.7 21.1 4.0 4.7 8.2 7.2 3.8 8.9 5.1 6.9 7.6 6.7 5.1 4.9 4.9 4.2 6.9 7.0 7.2 5.7 3.5 27.7 43.3 37.0 41.1 28.0 31.8 30.0 30.2 34.6 27.7 HYAL1 "FUS2, HYAL-1, LUCA1, NAT6" ENSG00000114378 "Hyaluronoglucosaminidase 1" Q12794 3 50299889-50312381 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 105.8" "Group enriched" "Detected in some" 4 "Hep G2: 44.8;SK-BR-3: 13.0" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 7.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" 15000 "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favourable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favourable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" 4.9 6.3 1.0 0.9 1.3 0.0 8.4 0.9 1.4 2.9 1.8 1.7 1.3 1.2 3.5 3.5 5.8 1.9 19.3 18.2 1.1 0.5 25.0 105.8 11.3 2.5 1.2 0.9 1.9 3.1 8.0 0.8 1.3 2.9 1.4 1.0 3.1 3.6 1.2 5.2 5.8 1.4 2.7 1.2 28.0 7.2 1.7 0.8 0.2 3.1 4.2 1.0 1.3 4.3 1.2 1.1 7.3 0.9 0.7 1.5 0.2 1.3 0.8 0.1 0.4 0.2 0.3 0.2 0.0 0.1 0.0 0.2 5.1 1.3 0.0 0.3 0.2 3.1 0.1 0.2 0.0 0.0 0.0 0.1 3.8 44.8 2.1 0.3 0.3 1.8 6.5 0.0 0.2 1.3 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.1 0.1 2.7 0.1 0.0 1.0 0.0 13.0 0.1 0.9 0.1 0.8 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.1 2.2 0.9 2.9 0.7 0.3 1.5 0.9 0.7 1.0 0.4 1.2 1.5 0.8 7.3 0.7 0.7 1.1 0.9 0.2 1.0 1.3 0.9 1.4 1.1 0.5 1.2 0.9 2.9 0.8 HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronoglucosaminidase 2" Q12891 3 50317790-50322906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 107.0" "Group enriched" "Detected in all" 4 "HUVEC TERT2: 67.2;TIME: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain "HPA036436: AB_10670104" "unprognostic (9.97e-3)" "unprognostic (2.60e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-3)" "unprognostic (3.44e-1)" "unprognostic (7.41e-2)" "unprognostic (7.93e-2)" "unprognostic (4.70e-1)" "unprognostic (1.44e-1)" "unprognostic (6.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (7.02e-3)" "unprognostic (5.62e-2)" 46.5 16.4 5.4 11.0 13.9 1.2 52.1 3.5 7.6 16.0 9.5 6.6 9.0 7.3 18.8 11.3 16.0 16.5 19.9 33.6 11.1 6.0 35.7 20.2 61.1 25.6 7.5 4.0 13.6 11.2 7.9 11.9 34.4 16.3 10.3 4.8 20.4 10.9 9.7 11.6 9.7 9.9 15.1 8.0 107.0 10.2 8.6 5.5 1.1 23.2 16.0 8.3 14.8 20.2 0.9 4.4 8.6 11.3 2.0 3.4 2.6 4.8 7.1 11.7 12.0 7.3 6.3 7.7 5.8 7.6 7.9 6.1 8.2 14.3 1.2 19.7 7.8 5.1 4.4 10.7 2.1 2.6 3.9 1.7 6.6 12.4 6.3 1.4 4.7 9.9 9.0 7.9 2.5 67.2 3.2 1.5 6.4 6.6 3.1 2.9 13.7 11.0 2.8 2.3 4.7 9.7 4.3 3.2 10.2 5.7 5.8 5.8 6.5 3.7 91.9 9.5 9.7 6.4 8.6 2.7 4.3 3.9 5.6 4.6 13.7 0.0 8.0 8.6 1.3 11.3 2.8 0.9 1.1 3.4 4.4 0.9 0.4 0.6 7.6 2.0 10.4 3.3 1.4 2.6 5.4 13.9 3.5 7.6 11.1 6.0 7.5 4.0 16.3 5.5 HYAL3 "LUCA-3, LUCA14, Minna14" ENSG00000186792 "Hyaluronoglucosaminidase 3" O43820 3 50292831-50299468 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 26.9;bone marrow: 48.8;brain: 12.5;testis: 31.1" "Cell line enhanced" "Detected in many" "HEL: 21.9;HMC-1: 39.3;THP-1: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.1;eosinophil: 26.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 26.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049402 Uncertain "Secreted to blood" "HPA049402: " "unprognostic (1.21e-3)" "unprognostic (2.55e-2)" "unprognostic (5.45e-2)" "unprognostic (8.19e-2)" "unprognostic (3.07e-1)" "unprognostic (1.65e-2)" "unprognostic (7.98e-3)" "unprognostic (7.36e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" "unprognostic (5.40e-2)" "unprognostic (5.71e-2)" "unprognostic (2.61e-1)" "unprognostic (8.09e-2)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "prognostic unfavourable (2.12e-5)" 3.5 4.2 6.3 3.1 8.8 48.8 3.3 11.4 12.5 4.2 3.6 3.8 6.1 3.8 2.7 5.1 5.6 3.7 5.4 3.4 6.4 5.6 2.9 7.0 3.2 4.2 5.3 5.6 4.3 3.7 2.6 3.1 3.6 11.1 4.9 2.9 3.7 6.7 5.6 3.9 3.0 4.1 4.6 3.4 2.8 6.6 31.1 2.7 3.0 3.3 5.1 3.7 4.8 3.8 1.1 4.2 26.9 2.1 1.0 2.2 1.2 2.2 2.5 1.4 1.6 3.0 1.6 0.9 2.4 2.2 3.1 2.3 3.4 2.3 1.9 1.2 2.8 2.4 2.6 5.7 1.1 4.5 1.3 21.9 6.7 2.8 2.1 2.3 39.3 3.2 4.4 3.1 2.0 3.1 1.6 2.4 1.4 1.3 0.9 13.9 1.1 6.4 0.9 1.9 3.5 3.7 0.9 1.8 2.1 3.5 2.8 1.9 1.9 40.4 4.2 2.6 1.9 8.4 1.4 1.1 2.5 1.5 2.3 8.4 2.2 12.1 2.1 26.9 0.7 1.1 1.2 0.9 2.2 1.0 4.2 1.1 0.6 0.8 0.7 1.0 0.7 1.1 1.3 1.2 6.3 8.8 11.4 12.5 6.4 5.6 5.3 5.6 11.1 2.7 HYAL4 ENSG00000106302 "Hyaluronoglucosaminidase 4" Q2M3T9 7 123828983-123877478 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 7.1;skeletal muscle: 8.3" "Cell line enhanced" "Detected in some" "BEWO: 4.4;CAPAN-2: 7.1;RT4: 16.6" "Cancer enriched" "Detected in single" 48 "testis cancer: 8.4" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA029453 Uncertain "HPA029453: AB_10601432" "unprognostic (5.19e-5)" "unprognostic (4.18e-2)" "unprognostic (4.82e-2)" "unprognostic (2.20e-1)" "unprognostic (4.14e-2)" "unprognostic (2.60e-1)" "unprognostic (8.24e-2)" "unprognostic (5.26e-2)" "unprognostic (8.15e-3)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (5.55e-3)" 0.1 0.3 0.0 0.0 0.0 0.7 0.2 0.0 0.5 0.0 0.1 0.0 0.1 0.4 0.4 0.2 0.0 0.4 0.0 0.0 0.6 0.1 0.4 0.0 0.0 0.1 0.6 0.0 0.1 7.1 0.2 0.0 1.2 0.0 8.3 1.4 0.2 0.0 0.1 1.0 0.2 3.4 0.4 1.5 1.0 0.1 1.3 0.6 3.3 0.6 1.0 0.9 0.1 0.3 0.6 0.1 0.4 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 7.1 0.3 0.3 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 16.6 0.2 0.1 0.0 0.9 0.0 0.4 0.2 2.4 0.1 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.5 0.4 0.6 0.5 0.5 0.4 0.5 0.5 0.2 1.3 0.7 0.9 3.3 1.0 0.6 0.6 0.3 0.1 HYI HT036 ENSG00000178922 "Hydroxypyruvate isomerase (putative)" Q5T013 1 43451003-43453989 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ductus deferens: 130.4;seminal vesicle: 80.0" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 38.7;WM-115: 32.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 21.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040092 Uncertain Approved "Golgi apparatus,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA040092: AB_10795374" "prognostic favourable (9.18e-4)" "unprognostic (1.67e-1)" "prognostic unfavourable (4.96e-4)" "unprognostic (2.68e-2)" "unprognostic (3.86e-1)" "unprognostic (4.40e-2)" "prognostic unfavourable (5.55e-4)" "unprognostic (2.75e-2)" "unprognostic (1.42e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (4.43e-2)" "prognostic unfavourable (2.75e-5)" "unprognostic (5.10e-2)" "unprognostic (7.93e-2)" "unprognostic (3.58e-2)" "prognostic favourable (2.72e-5)" 16.5 12.5 11.6 12.1 10.1 5.3 12.8 11.3 9.7 14.6 16.5 13.0 130.4 23.4 15.8 14.8 8.4 15.3 16.7 10.9 9.2 10.0 15.9 25.8 17.8 6.7 10.9 9.3 25.1 34.0 13.8 11.2 10.8 9.0 15.6 7.5 15.0 20.8 80.0 8.8 8.4 22.1 13.4 14.3 7.6 14.1 4.5 11.1 4.9 12.8 9.6 6.4 10.7 11.3 3.2 21.6 6.2 1.2 4.8 5.4 3.0 17.2 2.2 0.7 1.2 3.4 6.3 0.0 15.1 13.5 19.0 12.7 8.8 30.1 0.0 1.1 9.7 3.2 0.0 15.9 7.8 4.2 6.2 2.8 7.9 0.0 22.4 0.0 0.0 3.7 4.6 21.5 0.0 38.7 0.2 0.0 12.7 0.3 2.5 2.9 3.2 4.4 13.3 0.0 0.1 13.2 0.6 8.2 6.1 16.8 9.5 3.7 2.4 21.6 17.8 1.2 0.0 3.4 29.3 0.0 0.0 0.0 1.0 4.0 32.8 6.2 1.1 2.4 3.3 0.9 4.1 3.2 5.4 2.6 4.1 2.7 5.1 1.5 0.1 4.8 1.2 21.6 0.5 3.0 11.6 10.1 11.3 9.7 9.2 10.0 10.9 9.3 9.0 11.1 HYKK "AGPHD1, LOC123688" ENSG00000188266 "Hydroxylysine kinase" A2RU49 15 78507564-78537372 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 17.5;U-266/84: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 7.1" "Lineage enriched" "Detected in single" 8 "T-cells: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040706 Approved Approved Vesicles,Aggresome Vesicles Aggresome "HPA040706: AB_10795528" "unprognostic (9.26e-2)" "unprognostic (1.98e-4)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (2.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.00e-3)" "unprognostic (2.73e-1)" "unprognostic (5.16e-2)" "unprognostic (6.24e-3)" "unprognostic (6.37e-2)" "unprognostic (3.44e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (3.11e-3)" "unprognostic (3.90e-2)" 6.3 7.5 6.4 4.8 8.0 1.7 7.7 2.3 6.1 8.2 14.3 2.5 6.8 11.1 6.4 11.0 7.0 6.5 7.5 8.5 4.3 3.5 19.4 10.5 3.6 4.3 3.5 3.6 9.7 15.5 4.0 8.8 1.5 4.3 8.0 6.2 10.1 7.9 10.1 8.9 3.9 21.2 9.4 3.4 1.6 6.8 7.8 2.2 5.7 7.3 3.7 4.1 7.1 5.1 0.4 0.6 0.8 0.2 0.5 7.1 1.2 3.1 5.1 0.5 9.0 2.0 4.4 1.9 1.0 2.1 3.0 3.5 1.7 3.7 2.5 1.1 2.0 3.6 8.2 2.7 2.8 1.1 17.5 1.1 2.2 4.2 5.1 0.3 1.4 4.0 5.1 1.1 2.3 2.1 3.0 6.5 1.7 3.8 2.9 0.5 0.5 6.5 1.7 9.9 2.0 5.6 3.5 0.9 1.2 2.2 6.7 7.9 7.6 0.2 0.9 1.9 1.4 3.6 3.3 10.2 17.8 0.1 2.2 0.1 2.7 0.8 0.2 0.5 0.3 0.1 0.4 0.4 2.4 0.4 0.1 0.4 7.1 1.3 0.8 0.5 0.1 0.6 1.0 1.2 6.4 8.0 2.3 6.1 4.3 3.5 3.5 3.6 4.3 2.2 IARS "IARS1, ILRS" ENSG00000196305 "Isoleucyl-tRNA synthetase" P41252 9 92210207-92293756 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029806 Approved Supported Cytosol Cytosol "HPA029806: AB_10601818" "unprognostic (1.32e-3)" "unprognostic (2.94e-2)" "unprognostic (2.27e-2)" "unprognostic (8.23e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-2)" "prognostic unfavourable (4.98e-7)" "unprognostic (2.00e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-1)" "unprognostic (4.96e-2)" "unprognostic (3.67e-2)" "unprognostic (1.40e-2)" "unprognostic (2.88e-2)" "unprognostic (4.71e-2)" "unprognostic (2.21e-1)" "unprognostic (7.76e-3)" 20.6 31.0 19.1 21.1 28.5 13.8 24.8 24.5 32.1 22.8 23.7 17.5 25.8 13.6 31.9 24.8 29.7 23.8 15.1 26.0 21.4 18.5 24.5 29.9 24.4 24.1 21.6 20.6 28.4 42.8 57.4 29.0 21.1 31.6 23.6 26.7 17.1 25.2 27.7 47.4 25.4 18.8 32.6 20.0 23.1 29.0 18.7 16.9 25.1 52.3 26.7 28.8 22.1 20.5 14.5 15.3 1.9 7.3 18.6 18.6 9.7 35.9 37.3 20.9 32.8 34.4 38.8 33.0 38.2 36.5 30.3 37.1 13.1 23.2 48.9 15.0 58.9 45.0 64.3 49.7 38.3 30.7 23.9 29.8 32.1 23.2 72.7 40.6 22.0 37.8 55.9 52.8 87.4 31.8 52.5 44.5 42.5 26.2 37.5 15.8 33.8 34.5 26.3 31.7 23.5 25.0 18.1 26.7 22.1 25.9 28.5 36.0 22.8 25.4 23.4 22.4 28.0 36.9 31.0 32.6 41.6 25.9 52.4 31.3 41.3 1.9 6.7 0.5 14.7 7.3 18.6 14.5 14.5 14.9 15.3 10.7 14.7 15.3 0.8 18.6 6.2 6.2 12.9 9.7 19.1 28.5 24.5 32.1 21.4 18.5 21.6 20.6 31.6 16.9 IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094102-220148041 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease mutation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria 26000 Mitochondria "HPA024212: AB_1851363, HPA024594: AB_1851368, HPA024596: AB_1851370" "unprognostic (2.15e-2)" "prognostic unfavourable (1.04e-4)" "unprognostic (2.42e-3)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "prognostic unfavourable (9.24e-5)" "unprognostic (9.48e-2)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (8.87e-2)" "unprognostic (6.27e-3)" 25.9 39.3 18.0 17.9 16.9 6.7 31.9 15.1 20.8 16.9 26.2 14.8 24.3 18.9 21.5 16.8 23.8 18.8 16.5 40.0 17.5 12.6 29.5 37.3 16.8 25.9 15.6 16.0 20.5 20.5 42.5 15.3 26.2 17.4 18.5 24.9 15.0 22.4 22.3 57.8 22.2 23.4 17.7 15.7 16.1 18.5 15.7 13.7 19.5 17.8 25.9 20.1 24.9 18.7 16.8 20.0 17.2 19.0 18.5 22.6 16.8 37.7 35.4 20.4 20.0 30.8 31.1 49.1 23.0 24.8 25.5 20.7 34.0 39.5 34.9 31.2 28.5 36.7 28.2 28.7 29.5 24.1 34.0 17.3 29.0 38.2 19.1 27.5 18.8 22.4 29.3 27.5 28.5 24.7 42.7 20.3 33.3 20.9 21.6 19.8 26.4 23.5 19.2 40.6 55.8 36.7 25.4 11.0 30.9 34.8 54.1 35.8 62.6 31.1 25.3 25.1 21.0 33.7 38.5 17.4 26.7 25.4 26.6 21.6 27.8 17.2 16.7 15.1 16.8 19.0 22.6 16.8 18.4 22.0 20.0 13.6 20.8 19.0 3.3 18.5 14.5 7.3 19.7 16.8 18.0 16.9 15.1 20.8 17.5 12.6 15.6 16.0 17.4 13.7 ICK "KIAA0936, LCK2, MGC46090, MRK" ENSG00000112144 "Intestinal cell kinase" Q9UPZ9 6 53001279-53061802 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000791, HPA001113" Approved Approved "Nucleoli fibrillar center" "Nucleoli fibrillar center" "HPA000791: , HPA001113: AB_1851385" "unprognostic (1.75e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.82e-2)" "unprognostic (1.17e-3)" "unprognostic (5.11e-2)" "unprognostic (1.18e-1)" "unprognostic (8.28e-2)" "unprognostic (8.12e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (2.26e-1)" 9.8 28.2 10.1 6.5 10.7 2.8 13.4 14.3 12.7 11.5 12.3 20.1 6.6 11.3 10.6 6.8 10.4 9.2 8.3 9.6 10.8 7.7 5.4 9.6 8.2 5.5 13.3 8.1 11.8 8.2 9.0 5.3 44.3 12.3 12.2 13.0 9.7 20.7 12.7 5.9 10.1 14.2 13.7 16.8 6.2 15.0 5.6 12.6 14.8 7.6 7.0 7.9 10.6 9.1 4.5 4.1 6.2 3.1 3.2 5.0 2.1 5.2 2.0 10.3 7.0 6.4 10.1 11.9 4.7 8.6 7.6 8.7 2.8 1.7 3.8 2.8 14.3 3.5 12.2 4.9 10.1 13.2 4.8 2.9 2.4 15.0 3.2 3.5 3.8 9.0 5.3 3.2 3.7 7.1 5.4 15.8 17.3 4.5 3.7 4.3 3.9 4.3 5.9 4.5 5.1 3.1 3.8 16.6 7.4 4.6 11.4 6.5 6.6 7.4 5.8 12.2 5.7 4.5 11.6 4.4 3.1 1.5 2.5 3.4 5.9 6.2 3.1 5.6 5.0 2.3 4.8 3.7 3.6 4.1 2.9 4.5 4.2 3.6 1.7 3.2 2.5 4.1 4.8 2.1 10.1 10.7 14.3 12.7 10.8 7.7 13.3 8.1 12.3 12.6 ICMT "HSTE14, PCCMT, PPMT" ENSG00000116237 "Isoprenylcysteine carboxyl methyltransferase" O60725 1 6221193-6235972 "Enzymes, Plasma proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 126.5" "Low region specificity" "Detected in all" "HPA032024, HPA032025" Uncertain "HPA032024: AB_2674115, HPA032025: AB_10601819" "unprognostic (1.95e-3)" "unprognostic (3.83e-2)" "unprognostic (7.34e-2)" "unprognostic (4.40e-2)" "unprognostic (5.53e-2)" "unprognostic (9.30e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (2.30e-2)" "unprognostic (7.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.87e-1)" "unprognostic (6.58e-2)" "unprognostic (2.11e-2)" "unprognostic (4.11e-1)" "unprognostic (5.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.99e-3)" 19.0 20.9 11.2 11.4 22.6 3.2 37.4 20.1 19.8 19.8 16.6 12.9 13.3 17.3 18.0 19.7 19.0 15.1 17.7 28.5 11.5 10.3 23.5 14.5 17.2 13.9 13.9 8.4 8.7 20.2 26.2 24.0 20.3 12.7 16.2 16.0 21.5 15.4 18.2 41.3 16.9 22.8 19.8 11.1 11.3 13.5 9.1 7.8 13.0 18.1 30.3 17.2 15.4 13.6 4.1 6.2 4.1 5.1 4.6 7.4 3.9 12.5 11.7 16.1 15.7 49.4 19.7 6.9 30.3 20.4 18.0 13.8 12.5 10.2 13.8 11.6 23.9 17.1 18.3 12.8 19.2 27.4 17.7 9.4 17.2 9.5 9.7 14.8 13.4 12.6 8.6 18.9 7.2 14.0 9.1 10.9 20.3 7.9 14.8 10.3 10.8 16.3 12.5 22.7 8.0 21.7 9.3 21.9 10.7 14.9 35.3 12.9 9.2 12.5 17.3 20.6 8.1 24.0 21.7 10.2 19.7 11.0 10.1 34.4 10.6 4.1 4.2 3.6 7.4 5.1 6.5 2.7 6.0 7.3 3.9 4.1 5.4 4.5 1.8 4.6 4.0 6.2 3.4 3.9 11.2 22.6 20.1 19.8 11.5 10.3 13.9 8.4 12.7 7.8 IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574076 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Intracellular and membrane" 140000 "HPA063478: " "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favourable (3.69e-4)" "prognostic favourable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" 9.8 13.1 6.9 11.7 8.8 6.0 19.8 8.6 9.4 10.5 9.9 6.5 17.5 7.4 10.2 15.9 13.0 8.4 9.6 13.6 5.8 5.3 13.3 21.3 7.9 9.2 8.9 5.1 7.7 15.7 19.4 11.1 9.4 7.6 11.6 10.0 10.5 11.0 17.2 31.1 45.2 10.7 14.3 8.8 9.9 10.3 18.1 7.5 13.5 12.0 13.9 10.7 11.5 9.8 7.4 11.3 3.8 13.7 7.7 10.6 5.5 12.2 18.1 14.1 29.0 13.8 11.6 7.8 10.8 25.7 11.4 9.7 18.4 14.5 17.3 16.0 15.8 15.8 18.6 11.9 7.5 20.7 11.4 8.6 15.1 16.1 12.1 26.2 13.6 8.2 11.6 13.4 19.4 19.2 16.0 12.3 12.9 8.2 8.7 10.3 11.2 7.2 12.1 13.2 11.0 16.8 22.9 6.6 9.2 14.6 10.5 9.5 15.0 7.4 17.8 7.4 8.4 7.7 13.9 11.3 14.1 18.5 10.8 21.0 5.1 2.3 8.2 3.8 6.7 11.4 5.9 7.4 7.9 6.5 11.3 5.3 6.0 6.4 0.5 7.7 13.7 4.4 10.6 5.5 6.9 8.8 8.6 9.4 5.8 5.3 8.9 5.1 7.6 7.5 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1, cytosolic" O75874 2 208236227-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 108.5;RT4: 75.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" 16000000 "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: , HPA035248: AB_10600714, HPA057936: " "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavourable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavourable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 41.3 82.3 6.2 8.8 7.0 1.3 20.9 6.5 8.3 12.6 35.2 8.7 38.0 30.6 8.0 29.9 30.3 8.8 18.7 10.8 6.3 6.2 20.5 91.0 19.8 14.3 8.1 4.7 19.4 21.5 4.8 6.2 24.1 8.7 38.5 23.1 15.4 18.7 39.0 4.7 7.4 54.1 10.1 9.3 21.3 20.4 15.6 8.4 3.5 7.9 11.0 11.9 43.4 12.1 4.9 22.8 6.4 31.6 7.4 6.6 12.0 9.6 16.2 23.2 9.4 42.2 30.1 13.2 4.0 18.4 6.8 16.6 25.6 23.6 1.9 25.6 12.5 14.9 16.7 19.4 6.6 1.3 6.3 8.3 13.4 108.5 56.2 5.4 8.3 25.9 41.3 15.5 11.3 18.7 8.3 6.7 10.4 6.1 3.8 9.3 42.4 6.7 3.7 8.4 5.4 30.6 75.8 4.0 6.9 15.3 14.8 50.1 5.7 15.8 12.3 6.9 7.0 9.8 4.3 3.2 5.0 2.5 22.4 32.8 5.5 5.7 31.6 4.8 4.5 14.5 5.1 4.9 4.0 5.3 22.8 4.9 3.3 3.9 6.4 7.4 6.5 8.4 6.6 12.0 6.2 7.0 6.5 8.3 6.3 6.2 8.1 4.7 8.7 8.4 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2, mitochondrial" P48735 15 90083045-90102504 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 126.2;skeletal muscle: 190.7" "Cell line enhanced" "Detected in all" "MOLT-4: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria 53000000 Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favourable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 5.4 2.0 14.9 10.1 16.6 22.6 8.8 4.9 19.1 6.4 16.2 13.8 12.4 16.1 5.9 15.3 23.7 6.0 9.4 126.2 10.2 9.3 25.0 93.2 6.9 15.8 14.4 12.0 3.0 25.1 8.4 3.3 15.1 11.9 13.3 14.5 6.0 28.0 21.9 190.7 11.0 13.9 15.8 11.0 7.5 27.9 1.2 7.6 28.2 3.4 69.0 13.6 11.0 8.6 16.8 32.8 17.2 56.3 22.2 29.5 31.2 10.2 5.8 30.2 30.0 4.2 5.2 25.7 12.8 19.5 12.1 13.0 2.7 8.9 12.2 3.6 10.6 3.5 4.4 3.9 5.8 23.9 2.9 20.8 2.2 20.3 5.1 14.2 21.1 10.8 2.2 2.9 2.3 24.8 3.1 10.5 9.3 29.8 68.3 22.1 9.0 2.4 57.9 21.7 36.3 18.7 12.3 43.6 22.1 15.9 63.6 5.1 51.3 43.9 5.9 21.7 3.1 2.8 5.9 17.3 3.2 1.4 6.9 30.0 12.5 9.0 26.4 17.2 26.1 48.0 12.4 16.8 18.7 29.5 32.8 9.8 10.2 18.2 5.1 22.2 56.3 17.8 15.9 31.2 14.9 16.6 4.9 19.1 10.2 9.3 14.4 12.0 11.9 7.6 IDH3A ENSG00000166411 "Isocitrate dehydrogenase 3 (NAD(+)) alpha" P50213 15 78131498-78171949 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 47.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041465, HPA062971" Supported Enhanced Mitochondria 2000000 Mitochondria "HPA041465: AB_10794377, HPA062971: AB_2684913" "unprognostic (2.33e-1)" "unprognostic (1.21e-1)" "unprognostic (5.76e-3)" "unprognostic (2.26e-1)" "unprognostic (1.02e-1)" "unprognostic (4.01e-1)" "unprognostic (2.29e-1)" "unprognostic (6.47e-2)" "unprognostic (1.69e-2)" "unprognostic (2.30e-1)" "unprognostic (3.05e-1)" "unprognostic (1.42e-1)" "prognostic favourable (6.49e-8)" "unprognostic (1.40e-1)" "unprognostic (3.08e-2)" "unprognostic (4.49e-2)" "unprognostic (3.39e-2)" 14.6 18.1 18.0 13.0 25.3 6.5 7.7 16.1 29.5 9.9 17.6 11.9 6.1 24.5 11.2 5.9 12.0 8.4 6.5 41.5 16.6 16.8 15.2 10.4 8.8 11.0 20.6 18.1 8.0 9.2 18.5 12.4 8.4 29.0 10.1 18.8 10.4 11.2 11.9 47.7 11.1 23.8 11.9 18.1 10.1 8.9 11.5 13.8 16.2 8.1 26.5 16.4 11.1 10.3 10.1 47.2 6.1 17.0 5.5 6.0 7.4 15.9 21.9 4.0 13.9 10.0 10.2 8.7 19.0 9.3 15.5 11.8 15.5 9.7 34.0 14.1 11.1 24.1 36.9 14.7 14.4 14.9 12.2 13.1 23.7 7.0 8.5 25.4 18.8 7.7 9.1 15.1 15.9 9.7 16.8 14.0 9.8 15.2 18.6 6.8 4.9 8.2 10.8 17.0 10.6 12.9 21.7 15.9 6.1 21.8 31.2 17.6 12.4 13.8 10.0 18.3 17.0 24.1 30.6 16.0 35.6 18.1 12.9 24.3 14.3 4.2 9.4 2.7 5.3 17.0 5.7 9.2 5.2 4.8 14.2 10.1 5.6 6.0 6.1 5.5 16.6 47.2 5.6 7.4 18.0 25.3 16.1 29.5 16.6 16.8 20.6 18.1 29.0 13.8 IDI1 ENSG00000067064 "Isopentenyl-diphosphate delta isomerase 1" Q13907 10 1039152-1049170 "Enzymes, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039169 Approved "HPA039169: AB_10674280" "unprognostic (1.61e-2)" "unprognostic (2.59e-2)" "unprognostic (4.58e-2)" "unprognostic (1.97e-1)" "unprognostic (5.72e-3)" "unprognostic (1.27e-1)" "unprognostic (1.76e-2)" "unprognostic (1.97e-1)" "unprognostic (3.72e-2)" "unprognostic (3.88e-2)" "unprognostic (2.59e-1)" "unprognostic (2.26e-1)" "prognostic favourable (1.46e-4)" "unprognostic (9.63e-2)" "unprognostic (2.01e-2)" "unprognostic (2.19e-3)" "unprognostic (2.61e-2)" 13.6 30.4 23.1 15.2 28.3 47.8 68.8 16.4 39.2 8.8 16.1 22.5 8.0 27.9 7.7 12.6 19.2 6.5 9.9 9.7 23.0 29.2 15.3 67.6 15.6 15.5 21.7 25.3 13.4 13.7 12.3 20.6 10.0 55.9 22.3 15.0 16.9 9.9 7.1 35.1 13.7 17.6 8.3 30.6 17.5 12.9 10.2 14.4 8.5 9.8 16.8 16.3 12.5 11.1 16.1 8.9 36.4 19.6 14.5 18.4 14.8 25.2 9.4 50.5 12.3 21.1 46.2 7.4 10.6 12.0 12.3 26.2 24.8 39.6 22.9 7.0 11.5 22.0 28.0 50.2 11.2 7.8 26.5 22.2 14.2 28.3 24.7 8.5 11.0 29.1 21.1 34.3 4.6 9.6 15.2 32.2 20.7 19.7 16.3 14.1 20.4 5.6 19.1 24.1 25.4 53.5 22.3 7.9 9.5 13.5 27.9 27.8 28.9 28.9 9.6 6.8 3.8 19.8 7.6 18.7 17.6 43.0 8.5 25.5 6.1 36.4 9.4 21.9 18.2 17.1 18.4 16.1 14.2 15.2 8.6 14.9 10.7 15.8 25.1 14.5 19.6 8.9 14.9 14.8 23.1 28.3 16.4 39.2 23.0 29.2 21.7 25.3 55.9 14.4 IDNK "bA522I20.2, C9orf103, hGntK" ENSG00000148057 "IDNK, gluconokinase" Q5T6J7 9 83623049-83644130 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 35.9;liver: 39.1" "Cell line enhanced" "Detected in many" "MCF7: 19.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020378, HPA058429" Approved Approved Mitochondria,Cytosol "Mitochondria, Cytosol" "HPA020378: AB_1845794, HPA058429: " "unprognostic (1.49e-3)" "unprognostic (7.94e-2)" "unprognostic (3.30e-1)" "prognostic favourable (1.10e-6)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (5.41e-3)" "unprognostic (1.81e-2)" "unprognostic (6.08e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-2)" "unprognostic (3.00e-1)" "unprognostic (5.86e-3)" "unprognostic (7.32e-2)" "unprognostic (1.07e-1)" "unprognostic (2.55e-1)" "unprognostic (3.11e-2)" 4.3 6.1 9.4 2.9 20.3 2.2 4.5 12.3 8.3 2.3 11.3 7.0 3.1 14.2 2.5 7.4 4.1 6.8 4.5 2.8 7.6 8.6 27.2 39.1 3.7 4.7 7.3 6.3 3.2 6.6 3.6 5.2 1.8 6.2 4.2 4.7 5.2 4.6 5.0 1.2 3.3 20.2 3.5 7.0 4.2 4.3 2.0 6.8 14.5 7.0 1.2 4.3 2.8 2.1 17.5 9.6 35.9 20.5 15.0 23.0 11.4 3.4 8.4 1.1 1.3 3.8 5.5 6.1 2.4 7.0 2.6 2.1 2.2 3.1 4.4 4.1 3.7 5.9 0.9 1.6 2.8 9.6 1.0 1.6 3.3 9.6 16.7 1.0 2.0 3.7 2.2 5.8 5.5 6.0 1.3 4.6 3.9 19.3 2.7 1.1 1.0 3.8 3.3 3.2 2.5 7.0 4.0 5.4 6.9 5.6 4.4 5.9 4.4 5.9 6.1 1.2 0.8 10.9 4.5 6.8 7.8 0.6 6.0 1.8 2.1 35.9 6.1 8.6 14.7 10.6 12.3 17.5 12.7 12.1 8.5 11.4 10.2 13.8 1.1 15.0 20.5 9.6 23.0 11.4 9.4 20.3 12.3 8.3 7.6 8.6 7.3 6.3 6.2 6.8 IDO1 "IDO, INDO" ENSG00000131203 "Indoleamine 2,3-dioxygenase 1" P14902 8 39902275-39928444 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 77.7;placenta: 33.2" "Cell line enriched" "Detected in some" 7 "EFO-21: 35.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 17 "eosinophil: 77.7" "Lineage enriched" "Detected in many" 17 "granulocytes: 77.7" "Region enriched" "Detected in single" 13 "basal ganglia: 30.5" "Low region specificity" "Detected in all" "HPA023072, HPA023149, HPA027772, CAB072820" Enhanced Supported Nucleoplasm,Vesicles,Mitochondria,Cytosol Cytosol "Nucleoplasm, Vesicles, Mitochondria" "CAB072820: , HPA023072: AB_1846220, HPA023149: AB_1846221, HPA027772: AB_1846222" "unprognostic (1.68e-2)" "unprognostic (1.71e-2)" "unprognostic (4.08e-3)" "unprognostic (7.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.09e-2)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "prognostic favourable (5.27e-4)" "prognostic favourable (3.32e-4)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "prognostic unfavourable (1.12e-7)" "unprognostic (4.18e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.97e-2)" 8.7 0.2 0.9 11.2 0.9 0.0 1.4 0.9 0.9 4.0 1.5 0.9 0.9 2.6 2.6 0.9 1.2 0.6 1.3 1.0 0.9 0.0 0.9 0.9 16.8 14.1 0.9 0.9 0.9 0.9 0.0 0.9 33.2 0.9 1.6 2.1 1.9 0.9 0.9 2.5 0.3 5.9 0.9 2.0 6.2 2.2 0.9 0.9 0.9 7.2 0.9 8.9 2.3 0.9 0.0 4.6 77.7 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.4 2.5 0.1 0.3 0.0 35.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 77.7 0.0 0.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.9 0.9 0.9 0.9 0.9 0.0 0.9 0.9 0.9 0.9 IDS SIDS ENSG00000010404 "Iduronate 2-sulfatase" P22304 X 149476990-149521096 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 107.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA078003 Approved "Intracellular and membrane" 8900000 "HPA078003: " "unprognostic (9.88e-2)" "unprognostic (1.10e-2)" "unprognostic (6.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (4.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-1)" "unprognostic (9.76e-3)" "unprognostic (3.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" 11.6 20.4 92.9 12.1 81.5 16.0 12.0 30.4 107.9 13.1 9.3 15.0 8.1 9.1 17.8 29.5 11.3 14.8 12.3 16.2 83.6 42.7 10.5 7.0 17.9 12.5 36.7 51.8 22.6 10.6 19.5 17.8 7.4 33.0 14.0 10.7 7.7 9.1 19.5 8.9 12.9 11.6 14.1 21.0 14.1 10.6 3.8 14.7 1.9 13.2 4.9 14.7 11.4 8.6 8.7 11.7 63.4 16.6 8.5 18.2 13.3 14.3 16.3 7.2 4.2 7.9 14.1 3.0 8.3 21.8 7.7 14.8 3.3 10.8 34.5 22.2 12.3 8.4 6.9 13.0 10.0 12.4 5.9 3.7 5.3 1.9 6.1 5.9 33.3 7.7 7.0 16.7 11.0 12.2 1.7 25.2 11.4 18.3 5.9 3.1 5.6 11.2 3.9 6.5 6.6 9.9 3.6 9.6 22.2 3.2 7.4 10.2 2.3 2.6 14.3 10.2 10.4 16.5 22.4 17.7 13.9 25.2 45.9 14.2 7.2 23.9 13.8 39.6 18.2 14.9 13.5 8.7 11.2 13.6 11.7 6.6 7.5 11.3 63.4 8.5 16.6 8.8 16.9 13.3 92.9 81.5 30.4 90.7 83.6 42.7 36.7 51.8 33.0 14.7 IDUA MPS1 ENSG00000127415 "Iduronidase, alpha-L-" P35475 4 986997-1004506 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025901, HPA046979, HPA054254" Enhanced Supported Vesicles "Intracellular and membrane" 130000 Vesicles "CAB025901: , HPA046979: , HPA054254: " "unprognostic (3.62e-2)" "unprognostic (9.08e-2)" "prognostic unfavourable (3.13e-4)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-2)" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-2)" "unprognostic (1.89e-3)" "unprognostic (2.64e-2)" "unprognostic (4.61e-3)" "prognostic unfavourable (7.87e-5)" "unprognostic (2.24e-1)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "prognostic favourable (8.04e-5)" 11.0 15.0 14.7 12.0 15.3 10.8 12.9 36.5 15.7 12.4 9.2 10.9 16.9 17.1 13.0 13.4 7.7 12.1 15.9 8.9 13.4 6.5 13.4 10.7 12.8 11.2 11.6 10.0 14.6 22.6 13.0 15.2 4.0 12.8 14.5 6.0 14.1 20.2 15.8 6.2 16.8 11.8 7.3 9.0 15.3 21.3 4.7 12.6 7.6 14.0 3.4 10.0 10.4 11.2 0.8 4.1 0.0 3.8 3.1 4.5 1.1 3.0 5.7 0.0 2.4 13.2 4.7 8.7 8.3 7.3 2.8 1.7 2.0 9.8 1.3 9.3 5.6 1.9 0.3 1.1 0.6 8.3 0.4 4.9 5.9 0.7 5.5 4.0 13.2 9.0 4.1 2.3 0.0 2.0 2.4 0.1 2.7 3.3 2.7 4.2 1.9 5.4 7.5 0.0 1.4 4.6 6.1 0.1 3.8 0.9 0.0 4.7 6.7 3.4 8.6 15.4 1.7 8.6 2.2 32.0 3.6 1.6 7.5 5.4 3.7 0.0 3.5 0.0 3.3 2.7 4.5 0.6 2.7 2.6 4.1 0.8 3.4 2.0 0.0 3.1 3.8 2.5 1.3 1.1 14.7 15.3 36.5 15.7 13.4 6.5 11.6 10.0 12.8 12.6 IFIH1 "Hlcd, IDDM19, MDA-5, MDA5" ENSG00000115267 "Interferon induced with helicase C domain 1" Q9BYX4 2 162267079-162318703 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.5;BJ hTERT+ SV40 Large T+ RasG12V: 39.2;Karpas-707: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002656 Approved "HPA002656: AB_1079344" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (5.51e-2)" "unprognostic (3.85e-3)" "unprognostic (3.34e-1)" "unprognostic (1.39e-1)" "unprognostic (5.65e-2)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.62e-1)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.41e-2)" "unprognostic (7.29e-2)" 17.2 11.3 5.8 23.1 5.8 26.9 10.5 2.8 6.4 10.3 12.5 4.9 9.5 12.3 7.3 11.0 9.9 8.3 10.8 6.3 6.1 4.7 10.4 11.8 19.7 17.2 6.1 3.2 11.2 11.5 11.6 14.0 15.6 7.0 12.3 7.8 5.9 15.7 17.2 4.7 6.4 18.0 5.8 7.4 25.3 9.0 4.3 4.2 20.5 15.9 8.3 12.9 9.1 10.4 12.3 10.5 14.5 11.6 3.6 9.4 7.1 3.0 0.3 0.1 0.0 4.0 3.1 1.2 0.5 8.4 31.5 39.2 0.5 7.5 6.1 4.6 0.5 3.3 0.5 4.1 3.3 14.5 1.7 3.6 0.5 1.8 3.6 4.0 2.7 2.4 2.7 3.8 0.8 2.4 0.1 18.6 0.5 6.3 4.1 4.0 0.0 1.5 3.0 0.0 8.7 3.6 3.9 0.1 0.0 1.8 10.3 18.0 2.7 3.2 1.9 0.9 0.8 0.4 1.2 7.2 11.8 0.9 1.6 3.2 2.8 4.2 11.0 4.0 6.5 11.6 9.3 11.4 8.3 7.2 10.5 12.3 6.9 7.1 14.5 3.6 11.0 1.5 9.4 7.1 5.8 5.8 2.8 6.4 6.1 4.7 6.1 3.2 7.0 4.2 IGF1R "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSG00000140443 "Insulin like growth factor 1 receptor" P08069 15 98648971-98964530 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 7.7" "Group enriched" "Detected in many" 5 "granulocytes: 7.7;T-cells: 2.9" "Low region specificity" "Detected in all" "CAB010268, HPA045563" Approved Approved Vesicles 36000 Vesicles "CAB010268: AB_671792, HPA045563: " "unprognostic (1.30e-3)" "unprognostic (5.81e-3)" "unprognostic (1.53e-1)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (2.05e-2)" "unprognostic (1.29e-2)" "unprognostic (6.87e-2)" "unprognostic (2.64e-2)" "unprognostic (2.87e-2)" "unprognostic (8.56e-2)" "unprognostic (1.62e-1)" "prognostic favourable (3.75e-7)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" 8.4 12.7 11.5 5.9 13.5 16.3 18.5 23.0 15.7 15.3 13.4 10.4 22.7 4.2 15.3 16.3 9.2 18.9 7.7 11.6 11.7 7.3 17.0 2.0 11.0 4.9 8.0 11.8 23.2 22.5 4.7 13.8 17.5 9.5 21.7 7.2 16.7 12.5 23.2 9.1 13.0 7.5 18.1 8.0 7.3 10.7 12.0 11.5 10.7 16.1 7.0 5.6 12.8 21.6 1.0 0.4 7.7 0.6 1.0 2.9 0.7 3.3 16.5 11.6 0.2 5.8 4.2 7.7 3.7 7.4 1.2 1.1 7.1 8.8 0.8 10.7 7.2 15.8 5.1 15.0 1.0 0.0 5.2 12.5 18.5 14.2 5.1 6.6 1.3 6.6 7.1 2.1 10.2 4.1 0.6 2.9 5.7 23.4 2.5 4.4 10.8 0.9 4.0 9.0 3.0 3.5 20.3 3.9 17.3 26.7 1.5 14.4 8.1 3.1 11.3 1.1 15.0 3.0 5.8 1.0 4.4 2.7 2.2 4.9 2.8 4.0 0.6 1.8 0.9 0.6 0.6 0.4 0.8 0.3 0.4 1.0 2.9 1.0 7.7 1.0 0.5 0.3 0.0 0.7 11.5 13.5 23.0 15.7 11.7 7.3 8.0 11.8 9.5 11.5 IGHMBP2 "CATF1, CMT2S, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7" ENSG00000132740 "Immunoglobulin mu binding protein 2" P38935 11 68903842-68940602 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Ribonucleoprotein, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004092, HPA060994" Enhanced Nucleoplasm Nucleoplasm "HPA004092: , HPA060994: " "unprognostic (1.17e-1)" "unprognostic (1.04e-1)" "unprognostic (7.17e-2)" "unprognostic (3.96e-1)" "unprognostic (1.54e-1)" "unprognostic (1.69e-1)" "unprognostic (3.59e-3)" "unprognostic (4.31e-2)" "unprognostic (3.81e-1)" "unprognostic (1.19e-1)" "prognostic favourable (5.89e-4)" "unprognostic (1.03e-1)" "prognostic unfavourable (1.29e-8)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" 7.2 6.0 6.9 8.1 11.0 13.8 9.4 17.7 14.9 8.1 14.6 8.3 14.3 9.7 12.0 5.4 8.8 8.5 7.8 7.7 6.6 5.3 6.7 8.7 7.3 7.9 4.6 7.0 9.4 9.6 7.7 6.0 6.5 6.6 9.0 6.1 7.9 12.7 10.0 12.2 11.7 9.4 8.1 4.1 8.9 9.1 36.9 5.7 10.0 7.3 5.9 8.8 8.8 8.3 5.0 3.3 4.7 12.1 2.7 5.1 2.7 8.0 9.2 5.5 8.8 4.5 3.5 8.4 8.0 5.0 10.0 6.6 18.7 8.0 7.0 11.4 4.1 12.8 9.2 5.0 4.2 8.2 7.8 10.0 10.9 6.0 5.2 7.5 9.5 2.6 6.0 10.6 5.4 5.1 11.7 9.0 3.4 6.3 11.9 13.5 4.8 9.8 9.9 8.4 8.5 4.7 7.3 8.8 6.4 9.5 8.2 19.0 12.6 5.7 6.9 8.6 7.5 11.5 8.3 10.1 7.7 8.1 6.0 7.3 7.8 0.0 3.9 2.2 5.1 3.3 4.7 5.0 3.4 4.0 3.3 3.3 2.4 3.3 4.7 2.7 12.1 2.5 4.0 2.7 6.9 11.0 17.7 14.9 6.6 5.3 4.6 7.0 6.6 5.7 IKBKB "IKK-beta, IKK2, IKKB, NFKBIKB" ENSG00000104365 "Inhibitor of nuclear factor kappa B kinase subunit beta" O14920 8 42271302-42332653 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001249, CAB004447" Enhanced Approved Cytosol Cytosol "CAB004447: AB_627785, HPA001249: AB_1079126" "unprognostic (1.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.27e-3)" "unprognostic (1.95e-1)" "unprognostic (1.25e-3)" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.89e-2)" "unprognostic (9.20e-2)" "unprognostic (3.02e-1)" "prognostic favourable (1.46e-6)" 9.1 10.8 10.9 17.0 16.7 9.3 10.0 26.1 16.9 10.3 10.3 12.4 11.4 4.7 15.3 13.2 17.9 16.4 14.9 7.9 13.1 6.9 12.4 9.9 14.9 12.2 20.3 7.9 9.6 13.3 18.0 13.6 11.2 11.9 14.0 10.9 10.5 11.4 9.7 17.6 22.2 9.8 16.4 10.5 18.7 10.8 8.3 18.6 12.9 14.3 8.4 17.1 18.1 12.8 12.6 14.8 14.1 9.6 11.9 11.2 5.8 3.6 13.1 3.7 6.4 14.5 12.6 4.8 3.2 11.5 9.7 8.5 3.0 6.8 7.2 5.6 8.9 4.2 5.1 13.0 12.5 7.0 5.8 10.1 6.1 2.3 11.1 1.9 10.6 8.4 9.9 9.3 14.4 14.3 8.5 3.5 21.2 4.2 7.0 3.2 3.6 4.1 7.2 6.4 4.2 10.9 3.3 1.1 2.1 2.1 3.6 5.3 4.8 8.5 7.4 6.8 3.6 5.3 2.3 2.1 2.2 5.1 8.1 4.8 7.7 14.1 9.6 10.4 10.1 7.6 10.3 9.4 10.5 11.2 8.9 12.6 10.2 10.4 11.4 11.9 9.0 14.8 9.9 5.8 10.9 16.7 26.1 16.9 13.1 6.9 20.3 7.9 11.9 18.6 IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 24.8;lymphoid tissue: 19.5" "Cell line enhanced" "Detected in many" "NB-4: 25.1" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol Cytosol "CAB025983: , HPA015788: AB_1851566" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.76e-2)" "unprognostic (7.78e-3)" "unprognostic (7.37e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (5.34e-7)" "unprognostic (1.48e-2)" "unprognostic (5.77e-2)" "unprognostic (2.84e-3)" "unprognostic (2.84e-2)" 2.1 0.9 1.0 17.3 3.4 4.3 1.4 1.1 1.7 2.2 4.8 1.5 1.7 3.9 2.0 3.9 6.1 1.2 3.6 1.1 2.9 1.5 0.6 3.7 13.6 2.1 0.7 1.0 1.5 0.0 0.8 2.5 1.9 1.8 4.3 1.5 8.3 2.9 0.1 8.9 4.2 1.0 2.9 12.8 4.0 0.0 2.4 18.8 2.6 4.4 19.5 4.4 0.4 12.9 4.6 4.2 15.9 10.8 24.8 12.3 8.8 7.0 1.9 0.2 3.5 5.0 2.0 3.6 11.3 4.9 5.5 5.5 14.4 17.5 9.7 7.2 12.0 0.0 9.1 1.0 2.8 1.7 2.4 4.2 3.8 4.6 14.9 8.0 6.5 1.6 4.0 0.8 7.1 1.1 5.4 5.1 1.8 9.5 25.1 2.8 5.4 5.1 2.1 14.0 5.8 15.1 0.0 0.0 1.5 12.0 2.2 7.2 10.6 13.7 4.9 3.0 3.5 4.0 1.8 0.8 11.4 9.2 12.5 2.0 4.2 15.9 0.3 10.5 11.2 7.5 12.9 16.7 15.2 4.6 7.4 13.3 13.6 1.1 10.8 6.4 1.5 24.8 12.3 IL4I1 FIG1 ENSG00000104951 "Interleukin 4 induced 1" Q96RQ9 19 49889654-49929539 "Enzymes, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 38.6;testis: 48.8" "Cell line enhanced" "Detected in some" "EFO-21: 17.6;HDLM-2: 30.5;Karpas-707: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "MAIT T-cell: 38.6" "Group enriched" "Detected in many" 6 "monocytes: 13.0;T-cells: 38.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045598 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" "Nucleoplasm, Cytosol" "HPA045598: AB_10969138" "unprognostic (6.23e-2)" "unprognostic (1.32e-2)" "unprognostic (8.39e-2)" "unprognostic (1.50e-1)" "prognostic unfavourable (1.33e-4)" "unprognostic (5.61e-2)" "unprognostic (3.74e-3)" "unprognostic (7.03e-2)" "unprognostic (2.52e-2)" "unprognostic (3.84e-3)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "prognostic unfavourable (1.23e-10)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (6.44e-2)" "unprognostic (2.11e-3)" 5.4 3.3 4.0 30.9 4.6 7.1 4.1 5.8 5.6 4.6 4.1 5.5 2.9 8.2 5.9 3.4 4.5 8.2 5.4 4.2 3.9 3.5 11.0 3.5 6.7 15.5 4.0 3.2 6.2 3.7 1.5 5.1 6.8 4.3 5.3 3.8 3.9 4.1 5.0 6.2 3.4 7.4 3.8 7.2 7.6 6.2 48.8 4.4 14.6 4.1 4.4 12.3 6.5 4.9 0.2 4.1 0.1 13.0 0.4 38.6 3.0 0.5 0.6 0.4 0.4 0.0 0.4 0.1 0.3 1.0 0.7 1.0 0.3 1.0 1.7 17.6 0.2 0.3 0.2 0.0 0.1 30.5 0.1 0.8 0.0 0.2 0.1 0.6 6.3 0.5 0.2 0.3 0.0 1.3 0.1 24.7 0.0 0.2 0.3 1.0 0.2 0.1 0.5 0.5 1.7 1.2 1.5 0.3 0.4 0.2 0.4 0.3 0.2 1.4 1.5 3.7 0.5 0.0 0.5 2.1 4.6 1.0 0.5 0.2 0.4 0.1 8.0 0.1 2.3 13.0 38.6 0.2 5.0 4.3 4.1 0.1 0.1 0.0 0.1 0.4 1.6 0.4 0.2 3.0 4.0 4.6 5.8 5.6 3.9 3.5 4.0 3.2 4.3 4.4 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Cell Junctions,Focal adhesion sites" 130000000 "Cell Junctions, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: " "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favourable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 20.9 17.6 11.0 22.3 11.9 7.5 37.0 9.4 14.6 40.2 75.1 14.7 41.9 13.5 75.4 25.2 35.7 33.2 41.1 35.1 11.1 9.2 21.6 15.1 21.9 18.9 11.5 14.0 24.2 22.3 20.4 10.9 22.2 11.5 39.9 24.6 19.3 19.4 89.9 18.5 12.4 22.2 103.5 10.6 20.2 33.2 14.2 11.0 8.2 17.5 14.1 13.6 60.8 25.9 19.5 45.9 76.5 49.4 45.3 25.8 63.7 23.8 18.4 29.1 10.0 44.9 31.9 13.2 35.1 69.4 41.6 50.8 19.2 28.1 9.0 9.3 57.4 19.2 16.2 29.7 41.8 15.7 14.8 12.9 17.6 14.9 30.1 10.3 14.8 30.6 14.0 28.1 21.5 39.6 11.8 10.7 54.2 17.9 9.1 17.7 18.3 21.6 9.6 15.2 9.5 30.5 19.1 5.0 11.4 16.6 23.0 19.3 16.0 11.8 45.8 52.2 23.6 21.6 17.0 7.8 4.8 12.6 38.7 15.6 24.3 48.3 49.4 76.5 25.8 47.9 25.1 19.5 23.3 24.4 45.9 17.1 14.7 18.5 31.7 45.3 44.4 18.5 25.7 63.7 11.0 11.9 9.4 14.6 11.1 9.2 11.5 14.0 11.5 11.0 ILKAP "DKFZP434J2031, FLJ10181, PPM1O" ENSG00000132323 "ILK associated serine/threonine phosphatase" Q9H0C8 2 238170401-238203729 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004752, HPA056099" Uncertain Supported Nucleoplasm Nucleoplasm "HPA004752: AB_1851753, HPA056099: " "unprognostic (1.50e-1)" "unprognostic (1.62e-1)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "unprognostic (9.75e-2)" "prognostic unfavourable (1.04e-4)" "unprognostic (1.60e-1)" "unprognostic (3.07e-2)" "unprognostic (3.88e-2)" "unprognostic (1.37e-3)" "unprognostic (7.03e-2)" "prognostic unfavourable (9.89e-6)" "unprognostic (6.24e-2)" "unprognostic (6.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-1)" 17.0 17.1 19.4 31.3 22.2 34.6 24.2 34.1 23.4 18.7 23.4 29.5 22.0 20.5 23.0 22.7 19.4 19.0 21.8 20.9 20.6 19.8 17.8 20.8 27.1 25.7 23.9 21.4 22.1 24.1 17.5 24.7 18.1 22.7 21.5 18.9 20.2 19.0 24.9 32.8 19.4 19.0 26.5 19.8 22.2 18.1 21.2 25.5 23.9 22.6 19.0 24.8 18.1 26.1 18.9 20.7 24.1 18.1 17.4 23.8 16.2 17.7 11.6 17.1 16.7 13.3 8.9 17.5 18.8 12.8 19.0 16.6 10.7 9.5 11.4 4.9 13.6 15.2 22.1 15.6 19.4 20.2 21.9 29.4 11.4 23.5 20.6 18.8 23.3 9.3 10.8 20.2 20.4 14.2 22.6 7.4 16.2 21.3 18.9 25.6 15.9 11.1 23.1 34.9 10.4 14.0 8.5 25.2 12.4 12.7 13.7 30.0 10.7 19.6 12.8 18.6 16.9 24.9 19.9 13.2 13.2 20.5 15.2 21.1 15.7 24.1 15.1 19.6 22.5 18.1 20.1 18.9 20.0 21.0 20.7 18.5 23.8 18.6 5.3 17.4 15.1 15.8 22.4 16.2 19.4 22.2 34.1 23.4 20.6 19.8 23.9 21.4 22.7 25.5 IMMP1L "FLJ25059, IMMP1" ENSG00000148950 "Inner mitochondrial membrane peptidase subunit 1" Q96LU5 11 31432401-31509645 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058308 Approved "HPA058308: " "unprognostic (2.39e-1)" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.17e-2)" "unprognostic (9.67e-2)" "unprognostic (2.08e-2)" "prognostic unfavourable (7.97e-4)" "unprognostic (7.59e-2)" "unprognostic (4.66e-3)" "unprognostic (5.15e-3)" "prognostic favourable (6.72e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-2)" "unprognostic (4.66e-1)" "unprognostic (4.52e-2)" "unprognostic (1.37e-2)" "unprognostic (1.04e-3)" 9.1 16.6 25.4 11.6 27.8 8.8 15.4 28.4 18.5 10.0 11.3 11.7 12.8 12.1 9.6 25.6 8.4 7.7 5.1 20.4 21.7 17.4 16.2 11.9 10.7 11.2 16.1 12.1 14.0 23.8 7.2 18.2 8.7 11.4 11.2 8.3 17.4 13.6 12.0 39.8 10.1 10.3 9.3 13.2 7.6 10.8 13.8 12.6 17.6 10.0 13.3 10.8 6.8 7.5 16.4 20.0 14.8 1.7 16.9 21.7 7.8 10.7 15.7 41.7 12.4 5.6 3.8 7.8 14.3 3.2 6.0 4.6 12.0 8.3 11.2 10.0 6.1 12.5 14.3 10.8 9.1 15.1 30.3 13.3 23.5 15.3 6.0 17.3 12.8 3.2 9.7 3.5 7.7 6.4 21.2 13.6 5.7 13.4 21.8 24.9 8.5 13.8 17.2 36.0 10.9 20.4 13.3 11.5 13.2 16.6 8.3 14.2 18.9 17.8 3.0 14.1 14.0 10.9 22.8 12.4 25.7 19.6 18.5 11.8 13.8 9.0 1.7 14.8 15.6 1.6 14.5 16.4 14.0 15.5 4.0 15.0 17.7 21.7 0.3 16.9 1.6 20.0 16.6 7.8 25.4 27.8 28.4 18.5 21.7 17.4 16.1 12.1 11.4 12.6 IMMP2L "IMMP2L-IT1, IMP2" ENSG00000184903 "Inner mitochondrial membrane peptidase subunit 2" Q96T52 7 110663051-111562517 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026711 Approved Approved Mitochondria Mitochondria "HPA026711: AB_1851760" "unprognostic (2.55e-2)" "unprognostic (1.40e-2)" "unprognostic (4.29e-1)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "prognostic unfavourable (1.89e-5)" "unprognostic (5.64e-3)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (5.68e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.89e-3)" "unprognostic (1.32e-1)" "unprognostic (6.65e-2)" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" 12.4 12.4 7.9 7.3 10.8 2.9 11.8 5.4 9.1 12.4 11.1 5.7 10.6 5.2 23.8 10.4 8.0 11.5 5.8 8.6 7.1 6.0 23.8 17.7 7.4 4.4 5.7 6.1 14.4 10.0 13.4 15.7 8.0 6.3 13.8 5.8 31.6 11.6 15.8 18.6 7.5 10.9 14.4 5.6 5.3 9.8 9.0 5.6 8.2 16.7 8.3 9.5 11.0 9.2 18.1 11.7 5.8 8.4 24.3 15.1 5.1 7.8 4.7 2.8 11.7 7.6 7.7 5.0 5.4 5.5 3.6 3.8 2.3 9.2 12.9 14.9 4.7 4.4 3.0 10.9 6.0 8.0 3.1 4.4 18.7 6.4 11.6 8.1 0.5 13.4 14.5 1.5 10.1 4.7 14.1 10.0 2.7 5.4 10.8 9.1 2.8 7.4 2.3 23.5 6.7 13.2 3.3 3.3 10.4 2.3 11.1 30.0 4.5 4.7 3.0 5.6 5.8 5.6 6.5 5.7 1.5 7.9 6.1 3.8 29.3 5.8 5.1 1.6 6.4 6.4 11.4 16.3 10.8 7.2 9.4 18.1 15.1 10.5 0.2 24.3 8.4 11.7 6.4 5.1 7.9 10.8 5.4 9.1 7.1 6.0 5.7 6.1 6.3 5.6 IMPA1 IMPA ENSG00000133731 "Inositol monophosphatase 1" P29218 8 81657961-81686693 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037489 Approved Approved Nucleoplasm,Mitochondria 390000 Mitochondria Nucleoplasm "HPA037489: AB_10671757" "unprognostic (1.78e-1)" "unprognostic (3.59e-2)" "unprognostic (6.95e-3)" "unprognostic (2.15e-3)" "unprognostic (1.31e-1)" "unprognostic (6.27e-2)" "unprognostic (3.80e-1)" "unprognostic (2.46e-2)" "unprognostic (1.06e-1)" "unprognostic (4.68e-2)" "unprognostic (7.78e-2)" "unprognostic (6.26e-2)" "unprognostic (2.52e-2)" "unprognostic (5.87e-2)" "unprognostic (1.84e-1)" "unprognostic (2.42e-1)" "unprognostic (5.41e-3)" 10.8 10.9 16.2 10.5 20.9 20.8 9.2 11.2 29.7 9.4 22.4 15.3 4.7 20.1 10.8 12.0 17.2 10.3 11.0 22.3 17.6 19.7 25.5 29.4 9.8 14.3 18.9 20.7 12.1 8.5 8.6 20.1 7.2 27.3 10.6 25.4 14.8 8.9 7.3 11.2 5.0 23.5 15.0 19.1 12.9 12.2 30.5 13.8 16.2 20.3 12.0 13.7 10.5 10.7 13.2 8.2 24.1 7.5 13.6 12.9 7.2 5.7 15.8 11.0 8.3 6.4 10.2 4.5 16.6 12.0 14.9 18.0 7.4 9.1 21.8 13.3 11.8 4.4 12.7 5.7 20.1 22.8 13.0 16.4 8.7 9.2 11.6 16.4 16.8 9.7 8.3 11.4 22.6 16.2 14.8 18.5 14.9 3.6 20.8 9.5 4.7 16.9 9.8 8.3 8.9 17.2 18.6 4.5 19.0 10.9 2.9 19.9 9.5 13.2 12.5 12.3 15.7 9.5 20.5 21.7 25.8 30.5 14.3 9.9 16.8 24.1 4.7 19.5 9.9 6.6 12.1 13.2 10.1 10.7 5.0 9.5 10.7 12.6 7.5 13.6 7.5 8.2 12.9 7.2 16.2 20.9 11.2 29.7 17.6 19.7 18.9 20.7 27.3 13.8 IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030883 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 90.1" "Cell line enhanced" "Detected in many" "BEWO: 67.4;RPTEC TERT1: 32.6;SiHa: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 14.4;neutrophil: 18.7" "Group enriched" "Detected in many" 14 "dendritic cells: 5.3;granulocytes: 18.7;monocytes: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029561 Approved Approved Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA029561: AB_10601932" "unprognostic (1.16e-1)" "unprognostic (1.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.50e-2)" "unprognostic (4.25e-2)" "unprognostic (3.25e-3)" "unprognostic (4.26e-3)" "unprognostic (4.08e-2)" "unprognostic (1.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.56e-2)" "unprognostic (4.24e-3)" "prognostic favourable (0.00e+0)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (3.35e-2)" 6.2 2.8 1.5 5.2 1.9 6.9 10.7 0.3 1.5 6.8 12.2 0.7 1.6 5.6 7.3 3.0 40.3 4.1 17.5 20.1 1.4 0.5 41.3 21.0 6.5 4.6 2.2 0.3 3.1 90.1 1.0 5.7 35.6 1.3 17.5 7.8 3.4 9.8 2.5 55.0 30.4 9.2 40.0 1.4 4.8 13.5 1.5 2.0 3.1 8.0 31.4 10.3 22.6 14.7 0.7 5.3 18.7 6.8 0.1 0.6 1.8 6.9 10.8 2.9 5.2 3.8 2.8 67.4 1.8 4.8 0.8 1.1 8.6 5.6 1.5 4.3 2.6 4.8 3.4 1.8 0.2 8.2 4.2 0.0 14.2 7.4 2.2 11.9 0.6 6.4 9.7 2.6 1.3 1.0 1.7 0.0 2.8 7.0 4.8 6.3 10.2 8.2 8.2 8.1 7.1 32.6 3.9 3.9 0.0 40.7 9.2 3.9 8.7 14.9 0.0 1.5 2.8 19.9 1.8 5.6 14.8 4.1 6.4 8.0 2.5 3.3 6.8 14.4 0.4 4.9 0.2 0.7 0.4 0.1 5.3 0.2 0.2 0.3 18.7 0.1 3.0 3.7 0.6 1.8 1.5 1.9 0.3 1.5 1.4 0.5 2.2 0.3 1.3 2.0 IMPAD1 "FLJ20421, gPAPP, IMPA3" ENSG00000104331 "Inositol monophosphatase domain containing 1" Q9NX62 8 56957933-56993844 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" 560000 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 30.6 33.9 17.8 13.9 23.7 9.6 17.6 23.6 33.1 24.7 17.7 30.9 17.8 11.7 23.2 15.2 17.7 15.6 18.0 25.2 19.9 21.6 21.3 32.6 16.5 10.3 23.6 21.1 16.0 25.2 30.4 20.4 23.3 27.2 28.8 16.2 25.2 28.7 22.5 41.4 13.4 12.3 23.0 21.7 13.0 14.7 19.0 19.5 12.0 24.4 18.1 13.0 17.2 14.9 1.9 2.0 6.1 4.6 6.8 2.4 0.6 17.1 14.3 11.0 11.3 33.9 23.3 15.2 26.1 25.4 18.7 16.4 7.1 12.2 10.7 20.0 27.7 14.1 13.3 17.6 27.9 14.7 9.5 20.9 10.1 12.7 21.1 13.2 14.9 18.7 17.7 16.8 27.4 24.8 9.0 19.5 20.5 9.1 16.1 8.0 8.2 5.3 11.3 9.9 12.1 19.5 10.2 4.3 12.0 14.6 18.1 14.8 16.1 9.7 20.7 25.4 14.7 25.0 18.7 20.2 16.8 11.5 34.8 11.1 15.6 2.9 1.9 1.1 2.0 1.2 1.6 1.3 1.3 1.2 1.4 1.9 1.5 2.4 6.1 6.8 4.6 2.0 0.9 0.6 17.8 23.7 23.6 33.1 19.9 21.6 23.6 21.1 27.2 19.5 IMPDH1 "LCA11, RP10, sWSS2608" ENSG00000106348 "Inosine monophosphate dehydrogenase 1" P20839 7 128392277-128410252 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" "DNA-binding, Oxidoreductase, RNA-binding" "Disease mutation, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 21.6;eosinophil: 20.2;intermediate monocyte: 26.2;myeloid DC: 15.1;neutrophil: 49.9;non-classical monocyte: 31.0" "Group enriched" "Detected in all" 5 "dendritic cells: 15.1;granulocytes: 49.9;monocytes: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001400 Approved Supported "Cytosol,Rods & Rings" Cytosol "Rods & Rings" "HPA001400: AB_1079139" "unprognostic (2.84e-1)" "prognostic unfavourable (3.87e-4)" "unprognostic (2.23e-2)" "unprognostic (6.45e-2)" "prognostic unfavourable (7.31e-5)" "unprognostic (6.03e-2)" "prognostic unfavourable (1.12e-7)" "unprognostic (1.24e-1)" "unprognostic (7.45e-3)" "unprognostic (1.03e-2)" "unprognostic (1.79e-1)" "unprognostic (2.50e-1)" "prognostic unfavourable (1.78e-12)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "prognostic unfavourable (3.72e-5)" 26.0 7.4 7.5 20.7 8.5 24.5 37.1 7.7 10.2 11.3 10.9 3.6 12.4 5.2 8.5 6.5 14.6 9.1 7.6 12.6 7.6 5.0 7.5 3.5 14.8 31.2 5.1 5.8 10.7 20.3 5.2 12.0 7.2 9.9 12.1 6.3 19.5 20.6 11.4 3.5 11.9 8.8 12.3 6.4 25.1 20.6 7.1 5.6 3.9 5.5 11.2 9.7 14.2 9.9 4.1 15.1 49.9 31.0 2.8 6.4 11.7 25.1 21.6 3.2 24.2 13.7 10.0 9.2 17.2 10.9 14.8 9.6 15.7 8.1 16.0 5.9 25.6 19.3 18.3 24.3 7.4 5.8 20.4 10.6 16.0 11.1 12.5 13.9 5.0 11.8 11.6 15.0 14.9 17.4 10.5 12.1 4.9 17.3 9.7 37.4 18.3 25.4 11.7 6.0 33.2 6.5 8.1 13.0 13.1 11.1 88.5 15.6 10.0 27.0 15.9 24.9 9.1 13.0 12.2 9.1 8.4 20.6 12.7 30.9 15.1 2.3 21.6 20.2 5.9 26.2 6.4 4.1 4.7 5.1 15.1 2.4 2.8 3.4 49.9 2.8 31.0 1.5 5.2 11.7 7.5 8.5 7.7 10.2 7.6 5.0 5.1 5.8 9.9 5.6 IMPDH2 ENSG00000178035 "Inosine monophosphate dehydrogenase 2" P12268 3 49024325-49029408 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" "DNA-binding, Oxidoreductase, RNA-binding" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001400, CAB020717" Approved Enhanced "Cytosol,Rods & Rings" 19000 Cytosol "Rods & Rings" "CAB020717: , HPA001400: AB_1079139" "unprognostic (2.09e-2)" "unprognostic (2.91e-1)" "unprognostic (5.96e-2)" "unprognostic (1.20e-1)" "unprognostic (7.31e-3)" "unprognostic (1.56e-1)" "prognostic unfavourable (3.22e-4)" "unprognostic (1.30e-1)" "unprognostic (2.65e-1)" "unprognostic (2.17e-1)" "unprognostic (5.44e-2)" "unprognostic (4.24e-2)" "unprognostic (1.30e-1)" "unprognostic (3.85e-1)" "unprognostic (5.80e-2)" "unprognostic (2.24e-1)" "unprognostic (4.47e-2)" 25.0 21.5 16.1 25.7 15.4 23.9 47.0 9.7 21.1 34.7 24.9 15.1 19.1 18.9 29.5 19.8 40.1 51.9 33.3 29.3 13.0 11.2 21.4 29.4 19.9 52.5 18.1 13.0 89.0 88.8 19.1 16.6 23.2 15.6 33.2 31.7 10.8 22.1 22.2 61.4 40.7 17.8 34.1 15.2 23.7 22.2 15.3 15.4 31.2 29.8 51.3 33.4 30.3 32.1 31.6 18.8 6.2 16.8 21.6 34.8 16.0 39.6 22.9 31.8 32.8 47.6 86.9 30.9 27.5 44.6 66.4 56.6 39.8 35.8 72.4 19.7 33.1 27.7 65.6 55.9 58.2 19.0 21.9 53.6 33.8 36.4 40.8 56.8 22.1 77.2 61.6 63.4 115.3 46.6 32.0 41.0 53.4 32.2 48.0 39.5 41.2 46.3 21.0 33.5 71.0 37.8 25.7 20.6 20.3 29.9 33.8 49.7 41.9 25.3 23.4 29.1 54.0 70.7 70.5 39.8 28.7 34.7 33.6 63.4 28.4 6.2 10.1 4.0 17.0 16.8 31.7 31.6 23.3 19.6 18.8 31.1 34.8 28.6 4.4 21.6 13.9 14.5 15.5 16.0 16.1 15.4 9.7 21.1 13.0 11.2 18.1 13.0 15.6 15.4 INMT ENSG00000241644 "Indolethylamine N-methyltransferase" O95050 7 30697985-30757602 "Enzymes, Predicted intracellular proteins" Detoxification "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 73.5" "Group enriched" "Detected in some" 5 "CACO-2: 18.2;HHSteC: 7.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 22.2" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA061343 Approved "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA061343: " "unprognostic (1.70e-1)" "unprognostic (4.36e-2)" "unprognostic (5.26e-2)" "unprognostic (6.78e-3)" "unprognostic (1.59e-1)" "unprognostic (3.39e-4)" "prognostic favourable (5.72e-4)" "unprognostic (3.08e-2)" "unprognostic (3.94e-2)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (9.07e-2)" "unprognostic (4.97e-2)" "unprognostic (1.62e-2)" "unprognostic (1.43e-2)" "unprognostic (9.71e-2)" "unprognostic (1.58e-2)" 19.7 18.0 0.3 3.0 0.7 0.0 5.9 0.3 0.6 4.9 3.7 1.3 14.0 0.8 9.8 18.9 12.4 16.3 14.7 24.6 0.6 0.4 11.8 24.3 73.5 12.1 1.1 0.8 20.2 4.0 0.7 3.2 12.9 2.5 10.1 1.6 13.0 6.1 19.9 4.7 1.5 3.9 11.3 1.3 6.5 5.0 28.2 0.2 0.5 9.4 3.8 2.8 9.6 6.4 1.7 1.1 4.2 1.0 2.2 1.0 0.6 0.0 0.1 0.1 0.1 1.8 2.5 0.4 0.2 2.3 0.0 0.0 18.2 0.1 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 7.8 0.1 0.3 0.9 0.0 0.0 0.1 0.4 0.1 0.3 0.3 0.1 0.0 0.4 0.8 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.6 0.1 0.7 0.0 0.2 0.1 1.1 0.1 0.8 0.3 0.1 0.8 0.3 0.1 0.2 0.1 0.3 4.2 1.0 0.8 0.7 0.4 0.7 1.2 0.7 0.6 0.4 1.7 1.0 0.8 3.0 2.2 0.4 1.1 0.6 0.6 0.3 0.7 0.3 0.6 0.6 0.4 1.1 0.8 2.5 0.2 INO80 "hINO80, Ino80, INO80A, INOC1, KIAA1259" ENSG00000128908 "INO80 complex subunit" Q9ULG1 15 40978880-41116354 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis" "Actin-binding, DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041417, HPA041484" Enhanced "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA041417: , HPA041484: " "unprognostic (5.39e-3)" "unprognostic (2.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (3.92e-2)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (1.93e-1)" "unprognostic (6.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.69e-2)" "prognostic favourable (6.30e-4)" "unprognostic (1.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.72e-2)" "unprognostic (1.47e-2)" 14.0 10.6 11.8 13.9 13.4 20.7 13.9 29.5 13.0 12.3 13.2 17.4 11.5 11.3 14.9 13.4 15.1 12.6 12.4 10.6 12.8 7.8 12.1 12.9 14.8 13.4 10.2 10.3 15.4 17.8 18.8 13.3 16.4 12.1 12.5 13.9 13.8 11.9 15.7 23.0 16.4 13.2 13.3 9.5 14.5 12.3 13.9 11.6 18.1 13.3 12.6 15.8 13.9 13.3 5.2 2.3 0.9 2.7 5.7 3.4 1.5 9.1 9.1 7.9 7.7 12.5 10.5 9.2 8.5 14.0 13.0 11.3 11.1 7.7 9.8 6.9 13.0 18.0 14.5 14.9 13.8 11.3 7.5 12.2 12.7 8.4 12.0 12.0 12.0 10.4 13.8 10.4 27.7 12.4 13.6 8.5 8.7 7.6 8.7 8.0 8.3 10.0 13.5 8.4 7.9 9.8 19.3 10.6 7.2 6.2 13.8 5.8 7.8 14.6 14.2 10.3 9.4 13.1 13.7 9.4 6.4 16.0 12.2 17.8 8.5 0.9 2.7 0.6 2.7 1.7 3.3 3.2 3.4 3.0 2.3 5.2 3.4 3.2 0.9 5.7 1.2 1.8 2.6 1.5 11.8 13.4 29.5 13.0 12.8 7.8 10.2 10.3 12.1 11.6 INPP1 ENSG00000151689 "Inositol polyphosphate-1-phosphatase" P49441 2 190343470-190371665 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "eosinophil: 36.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036698, HPA036699" Supported Approved "Centriolar satellite,Cytosol" 15000 "Centriolar satellite" Cytosol "HPA036698: AB_10672226, HPA036699: " "unprognostic (1.08e-3)" "unprognostic (4.50e-3)" "unprognostic (3.87e-2)" "unprognostic (2.70e-1)" "unprognostic (7.85e-2)" "unprognostic (3.67e-3)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (2.96e-2)" "unprognostic (7.28e-2)" "unprognostic (2.41e-1)" "unprognostic (2.54e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "prognostic favourable (1.12e-5)" "prognostic favourable (5.70e-4)" 14.9 25.8 18.3 9.1 26.5 10.3 32.5 17.4 25.1 15.0 19.8 20.4 11.5 27.4 12.0 10.8 42.7 9.8 20.6 17.7 21.2 17.9 11.0 24.8 19.9 8.8 21.0 16.5 10.0 25.6 32.3 17.0 10.4 18.6 10.0 16.8 12.0 9.9 16.0 13.1 28.3 28.0 15.5 23.6 15.7 13.9 31.4 17.1 4.6 12.9 14.0 15.4 19.2 18.8 1.8 3.5 36.6 3.4 6.2 8.0 1.9 10.8 3.0 5.9 0.0 6.5 14.0 0.1 13.1 17.5 12.3 16.2 11.8 6.9 0.0 15.6 12.5 15.0 2.4 8.4 15.1 13.3 4.6 8.2 9.6 7.0 13.7 6.0 2.6 9.5 13.0 14.0 8.1 22.9 19.4 6.9 21.6 0.0 0.4 5.8 1.7 16.8 0.2 4.8 0.1 9.5 25.9 8.8 3.3 9.0 0.5 12.7 0.0 8.8 21.2 7.9 5.6 14.1 7.6 1.3 1.4 0.1 2.5 2.4 6.2 8.1 3.4 36.6 3.0 3.1 2.7 1.4 1.9 2.0 3.5 1.8 1.0 1.5 1.6 6.2 1.8 0.1 8.0 1.9 18.3 26.5 17.4 25.1 21.2 17.9 21.0 16.5 18.6 17.1 INPP4A INPP4 ENSG00000040933 "Inositol polyphosphate-4-phosphatase type I A" Q96PE3 2 98444854-98594390 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001628 Approved Approved "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA001628: AB_10961254" "unprognostic (3.45e-1)" "unprognostic (2.39e-2)" "unprognostic (1.74e-2)" "prognostic unfavourable (3.70e-6)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "unprognostic (1.15e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (9.65e-2)" "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (4.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" 9.0 15.0 11.4 13.5 23.1 12.3 7.0 24.0 28.4 7.5 8.5 8.3 3.8 7.7 8.2 5.7 8.4 6.7 11.0 10.8 12.9 7.8 8.1 7.2 13.5 17.0 6.1 19.8 8.3 8.2 12.7 7.0 8.6 17.9 6.8 8.6 16.1 9.3 7.2 13.6 7.3 12.1 10.5 10.4 24.0 8.4 6.4 6.8 17.6 8.4 2.7 13.4 16.8 6.9 0.8 5.9 3.8 5.1 5.8 6.4 1.8 6.4 5.4 10.0 8.1 5.8 6.6 10.1 5.7 5.0 6.1 6.2 7.0 5.7 4.2 6.4 8.2 6.0 7.2 5.6 4.9 13.8 6.1 4.8 4.9 3.2 5.2 9.1 17.9 5.9 5.2 5.8 5.1 8.5 4.4 34.5 4.5 7.8 13.9 8.2 9.5 5.4 6.0 7.1 26.9 2.9 20.0 6.6 8.7 6.4 5.3 5.1 2.4 7.3 8.0 7.0 9.0 5.5 3.9 24.5 14.2 2.9 5.8 8.8 6.0 2.0 1.8 3.8 5.5 3.9 6.4 0.8 3.1 3.7 1.9 0.2 4.3 4.9 2.0 5.8 5.1 5.9 1.6 1.8 11.4 23.1 24.0 28.4 12.9 7.8 6.1 19.8 17.9 6.8 INPP4B ENSG00000109452 "Inositol polyphosphate-4-phosphatase type II B" O15327 4 142023160-142847432 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 51.5;SK-MEL-30: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "memory CD4 T-cell: 19.2" "Group enriched" "Detected in many" 6 "NK-cells: 9.1;T-cells: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037681, HPA037682" Approved Approved Centrosome Centrosome "HPA037681: AB_10670389, HPA037682: AB_10671377" "unprognostic (9.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.25e-2)" "unprognostic (1.77e-1)" "unprognostic (8.24e-2)" "unprognostic (3.03e-3)" "unprognostic (5.76e-3)" "unprognostic (1.95e-2)" "unprognostic (3.16e-1)" "prognostic unfavourable (1.03e-4)" "unprognostic (8.58e-2)" "unprognostic (1.26e-2)" "unprognostic (2.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.58e-1)" "unprognostic (1.39e-2)" 15.4 4.7 8.4 8.5 12.5 2.2 21.2 5.1 10.3 28.1 7.1 1.8 5.6 5.0 19.7 18.4 9.1 9.2 8.7 18.4 5.9 6.1 6.1 2.0 9.9 10.8 5.5 8.9 15.4 4.0 2.3 3.8 6.2 4.6 8.3 5.8 1.7 4.9 6.8 10.8 4.7 7.3 10.2 3.1 7.0 7.0 19.6 2.4 8.2 6.5 4.9 7.4 15.8 14.6 0.0 0.0 2.2 0.1 9.1 19.2 3.7 9.1 3.8 2.5 1.2 1.9 1.2 0.5 11.1 13.0 2.8 5.4 1.0 51.5 0.2 3.1 9.9 14.0 0.0 12.9 6.7 0.0 0.3 2.2 1.4 0.0 0.6 0.4 1.7 2.1 1.8 2.0 6.8 1.6 0.0 0.5 6.1 16.3 0.3 0.0 0.1 2.8 0.1 8.6 0.4 3.9 17.0 0.2 0.2 1.2 3.9 22.9 11.8 1.6 1.0 6.6 8.1 9.7 0.1 0.1 0.0 0.0 1.5 10.0 17.0 2.2 0.1 0.0 3.3 0.0 6.5 0.0 19.2 8.5 0.0 0.0 13.2 5.7 0.2 9.1 0.0 0.0 9.8 3.7 8.4 12.5 5.1 10.3 5.9 6.1 5.5 8.9 4.6 2.4 INPP5A 5PTASE ENSG00000068383 "Inositol polyphosphate-5-phosphatase A" Q14642 10 132537820-132783480 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 8.4" "Lineage enriched" "Detected in single" 21 "granulocytes: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012285, HPA066549" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "HPA012285: AB_1851802, HPA066549: " "prognostic unfavourable (7.47e-4)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (1.68e-3)" "unprognostic (1.43e-1)" "unprognostic (3.25e-2)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (5.65e-2)" "unprognostic (4.35e-1)" "unprognostic (4.70e-2)" "unprognostic (1.70e-2)" "prognostic favourable (3.15e-4)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (8.91e-3)" "unprognostic (8.66e-2)" 13.6 11.8 10.3 11.3 49.8 5.8 10.3 40.7 20.8 17.4 24.0 10.1 11.5 12.9 25.8 13.9 20.3 15.2 13.6 48.8 9.5 8.5 9.4 7.2 13.8 6.0 9.2 10.4 13.1 11.6 8.9 9.4 19.0 9.1 17.1 11.7 17.1 8.5 16.9 43.7 11.5 14.8 27.9 10.6 8.9 14.8 14.9 16.6 4.2 9.5 12.1 7.8 19.4 22.4 0.3 0.1 8.4 0.2 0.0 0.3 0.6 18.4 7.4 12.4 11.9 18.9 13.4 10.1 19.6 15.1 12.8 8.6 17.4 7.6 1.6 7.6 20.7 10.5 13.4 8.2 15.4 5.6 7.8 2.7 9.2 23.6 13.8 6.7 6.5 9.0 8.2 8.2 15.7 8.8 3.9 9.9 6.8 15.0 1.9 21.6 5.6 13.2 3.9 8.2 2.9 10.7 10.6 2.9 10.1 9.8 14.5 11.8 9.3 16.2 7.4 8.3 9.6 11.0 11.4 2.0 9.2 5.7 8.0 4.6 3.5 8.4 0.2 1.1 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.0 1.5 0.0 0.2 0.0 0.3 0.6 10.3 49.8 40.7 20.8 9.5 8.5 9.2 10.4 9.1 16.6 INPP5B ENSG00000204084 "Inositol polyphosphate-5-phosphatase B" P32019 1 37860697-37947057 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028803 Approved Approved Cytosol Cytosol "HPA028803: AB_10612121" "unprognostic (2.28e-2)" "unprognostic (8.91e-3)" "unprognostic (7.67e-2)" "unprognostic (2.27e-1)" "unprognostic (4.30e-2)" "prognostic favourable (1.11e-4)" "unprognostic (1.67e-2)" "unprognostic (1.52e-2)" "unprognostic (4.75e-2)" "unprognostic (1.85e-1)" "prognostic favourable (5.33e-4)" "unprognostic (8.27e-2)" "prognostic unfavourable (6.11e-5)" "unprognostic (1.03e-1)" "unprognostic (2.00e-1)" "unprognostic (2.51e-1)" "unprognostic (1.28e-1)" 14.5 10.2 11.7 15.9 18.2 22.3 12.8 25.4 16.1 15.3 18.3 21.0 9.4 9.3 19.5 13.7 9.9 15.0 13.7 14.3 12.2 9.0 11.7 16.2 18.7 21.1 23.2 11.4 28.7 11.4 13.1 14.4 14.3 15.9 12.0 13.7 18.9 9.4 16.0 9.7 12.0 13.9 17.5 18.5 19.0 14.7 8.6 21.8 17.4 13.8 4.7 22.3 17.4 13.2 6.7 5.3 19.1 4.7 5.3 9.1 3.8 3.7 2.8 6.6 10.5 8.2 10.6 11.6 4.6 8.1 5.8 8.4 4.3 5.6 13.8 2.2 8.4 5.1 8.6 3.3 7.7 8.9 3.8 21.0 9.0 2.8 12.0 11.1 30.5 12.4 2.1 6.1 3.9 7.0 7.1 18.0 8.0 3.2 8.9 11.8 9.2 2.2 10.9 13.0 6.5 3.4 3.4 2.6 4.5 4.9 2.3 12.0 2.9 9.8 6.9 5.9 5.5 5.5 4.2 14.7 7.1 11.1 7.0 10.4 5.0 19.1 2.5 13.2 6.3 2.0 9.1 6.5 4.5 6.1 5.3 6.7 5.8 5.3 3.4 5.3 4.7 4.8 5.6 3.8 11.7 18.2 25.4 16.1 12.2 9.0 23.2 11.4 15.9 21.8 INPP5D "hp51CN, SHIP, SHIP1" ENSG00000168918 "Inositol polyphosphate-5-phosphatase D" Q92835 2 233059967-233207903 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.9" "Cell line enhanced" "Detected in many" "HEL: 31.2;HMC-1: 32.8;hTCEpi: 30.0;NB-4: 29.3;THP-1: 20.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016300, HPA070455" Enhanced Approved Cytosol Cytosol "CAB016300: AB_628250, HPA070455: " "unprognostic (5.29e-2)" "unprognostic (2.05e-3)" "unprognostic (1.99e-2)" "unprognostic (6.71e-3)" "unprognostic (1.10e-1)" "prognostic favourable (2.03e-5)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" "unprognostic (3.74e-1)" "unprognostic (2.56e-1)" "unprognostic (1.23e-1)" "unprognostic (1.14e-2)" "unprognostic (1.66e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (6.54e-2)" 7.1 3.1 7.2 33.0 10.7 24.6 4.7 1.7 6.9 3.6 3.7 12.5 0.7 3.5 4.1 2.9 3.3 3.3 6.7 3.2 6.6 9.1 5.1 3.3 8.0 26.1 8.8 2.6 1.9 2.1 1.6 3.4 7.4 7.6 4.5 4.5 3.3 18.8 3.0 1.9 3.4 15.8 3.4 17.6 40.9 4.1 2.4 9.5 16.7 3.1 3.4 32.3 6.2 3.5 14.5 12.0 10.5 18.2 11.9 16.7 14.0 0.0 0.0 0.2 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.4 5.9 0.0 0.0 0.0 0.0 15.1 0.0 5.0 0.0 31.2 0.0 2.9 0.2 9.4 32.8 0.6 30.0 0.1 3.3 4.3 0.1 2.7 0.1 0.0 4.3 29.3 1.0 0.0 9.1 0.0 2.1 0.0 1.8 0.0 0.0 0.0 0.5 0.0 0.0 20.9 3.6 0.0 0.5 0.0 0.0 0.0 1.6 9.0 0.0 12.1 0.0 9.8 9.8 10.5 16.7 15.8 11.4 14.5 7.5 12.3 12.0 13.9 6.3 8.8 9.9 11.9 18.2 6.0 10.2 14.0 7.2 10.7 1.7 6.9 6.6 9.1 8.8 2.6 7.6 9.5 INPP5E "CORS1, JBTS1, pharbin, PPI5PIV" ENSG00000148384 "Inositol polyphosphate-5-phosphatase E" Q9NRR6 9 136428619-136439823 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Ciliopathy, Disease mutation, Joubert syndrome, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065758 Approved "HPA065758: " "unprognostic (1.99e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-2)" "unprognostic (1.23e-2)" "unprognostic (4.00e-1)" "unprognostic (6.92e-2)" "unprognostic (9.60e-3)" "unprognostic (3.21e-1)" "unprognostic (5.81e-2)" "unprognostic (2.65e-2)" "prognostic favourable (1.82e-4)" "unprognostic (2.03e-1)" "unprognostic (3.04e-2)" "unprognostic (3.76e-1)" "unprognostic (5.48e-2)" "unprognostic (4.64e-1)" "unprognostic (2.66e-2)" 14.3 11.2 14.9 15.3 10.4 8.9 19.2 19.9 19.1 10.5 10.7 11.5 11.1 10.3 13.1 10.1 8.4 17.2 9.4 11.9 12.6 12.0 10.2 9.0 10.1 13.5 8.4 12.3 14.7 11.6 11.4 12.3 9.8 13.2 9.9 5.2 11.0 14.4 12.9 11.6 18.2 10.7 10.7 6.6 19.4 8.6 15.2 10.3 8.5 12.5 6.2 10.7 8.8 19.3 2.6 1.0 1.9 0.5 0.0 2.4 0.6 6.1 7.1 8.3 8.2 4.2 5.5 10.3 7.3 4.3 5.7 3.6 7.2 4.3 7.6 7.6 6.1 17.2 3.7 5.1 2.2 23.9 14.4 5.1 12.2 4.8 7.2 6.0 8.3 5.9 4.7 6.3 5.6 5.5 8.6 7.0 4.8 10.1 7.6 13.2 5.4 11.8 14.1 6.4 5.7 5.1 6.0 8.8 7.8 7.1 6.7 5.1 10.7 8.9 7.9 17.6 6.6 7.1 12.8 7.6 6.1 3.2 9.0 5.3 6.4 0.0 0.5 1.9 2.0 0.0 1.3 2.6 2.3 1.5 0.5 1.7 0.8 1.6 0.4 0.0 0.3 1.0 2.4 0.6 14.9 10.4 19.9 19.1 12.6 12.0 8.4 12.3 13.2 10.3 INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726097-119829278 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 69.7" "Cell line enhanced" "Detected in many" "AF22: 36.0;SH-SY5Y: 28.5;SK-MEL-30: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" 4.6 12.3 17.5 5.9 50.4 3.2 5.7 37.0 52.9 10.9 5.0 5.5 2.2 3.1 11.8 18.0 4.5 4.2 5.5 4.1 24.6 53.1 7.3 2.0 4.2 7.6 23.7 29.1 9.8 4.6 8.9 34.0 8.2 69.7 8.3 6.1 3.4 7.1 8.4 7.5 10.4 3.8 10.8 19.2 4.1 3.8 10.1 7.3 1.4 8.4 1.4 9.3 5.3 4.5 12.2 7.4 1.5 4.5 3.8 6.7 2.2 4.6 3.3 36.0 5.2 3.9 4.0 3.1 6.5 3.6 3.1 3.0 4.8 5.9 3.0 2.5 8.1 5.2 3.9 3.8 4.7 1.9 3.6 2.0 1.6 4.8 5.5 1.3 6.7 4.8 3.5 6.1 6.1 10.4 1.8 4.8 7.3 2.6 1.8 5.4 3.4 4.1 2.4 6.4 0.8 5.2 2.4 2.6 28.5 7.2 2.2 54.3 1.5 1.4 6.9 3.1 4.1 4.0 6.3 5.4 2.4 1.4 3.9 4.6 12.6 1.1 4.0 1.5 1.3 3.5 1.6 8.1 2.8 1.9 7.4 12.2 3.2 1.4 1.0 3.8 4.5 1.8 6.7 2.2 17.5 50.4 37.0 50.5 24.6 53.1 23.7 29.1 69.7 7.3 INPP5J "INPP5, PIB5PA, PIPP" ENSG00000185133 "Inositol polyphosphate-5-phosphatase J" Q15735 22 31122731-31134696 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 65.2;thyroid gland: 71.2" "Cell line enhanced" "Detected in many" "HL-60: 12.1;SK-BR-3: 26.2;T-47d: 16.5;U-698: 11.4" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 63.1" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 2.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034539 Approved Nucleoli,Cytosol Cytosol Nucleoli "HPA034539: AB_10670974" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-2)" "unprognostic (2.21e-3)" "prognostic favourable (1.47e-5)" "unprognostic (6.81e-2)" "unprognostic (1.86e-2)" "unprognostic (4.29e-4)" "unprognostic (1.47e-1)" "prognostic favourable (1.12e-7)" "unprognostic (2.79e-3)" "unprognostic (3.65e-2)" "unprognostic (2.14e-1)" "unprognostic (1.39e-2)" 0.8 0.9 4.6 0.8 6.3 0.5 3.7 27.4 13.4 1.5 6.4 0.8 16.7 7.9 1.3 0.8 1.0 1.0 1.0 9.5 7.4 2.0 9.5 0.5 1.5 0.7 2.3 4.6 0.8 5.3 65.2 3.7 0.5 5.5 3.5 2.2 5.6 15.5 19.2 1.6 1.7 21.7 1.2 0.9 0.6 3.8 1.6 1.1 0.0 71.2 0.0 0.7 1.1 0.9 0.3 2.4 0.0 0.4 0.0 0.0 0.2 1.3 1.3 0.8 1.4 0.2 0.1 0.7 0.5 0.5 2.6 2.6 0.7 0.8 0.0 0.6 0.2 1.5 1.6 0.7 1.1 0.0 4.2 0.0 5.5 0.2 0.5 12.1 0.1 0.1 0.8 2.2 0.2 0.1 1.1 1.8 0.0 4.0 0.1 0.0 1.4 0.2 0.0 0.3 2.8 1.1 1.6 6.4 4.8 1.0 26.2 0.3 16.5 1.0 0.0 0.1 4.8 0.5 0.3 0.0 2.0 11.4 0.4 0.0 2.0 0.0 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.2 4.6 6.3 27.4 13.4 7.4 2.0 2.3 4.6 5.5 1.1 INPPL1 SHIP2 ENSG00000165458 "Inositol polyphosphate phosphatase like 1" O15357 11 72223701-72239105 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Immunity" "Actin-binding, Hydrolase" "Cancer-related genes, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037601 Approved Supported "Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" "HPA037601: AB_10672281" "unprognostic (2.68e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.68e-3)" "unprognostic (1.58e-1)" "prognostic unfavourable (7.37e-4)" "unprognostic (2.49e-2)" "unprognostic (3.54e-2)" "unprognostic (1.51e-2)" "unprognostic (1.64e-1)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (2.88e-1)" "unprognostic (1.99e-3)" "unprognostic (2.07e-1)" 20.9 23.7 22.2 20.4 19.5 25.1 18.6 11.1 18.9 25.2 32.0 22.7 28.8 19.8 24.7 18.4 17.4 24.3 29.6 29.5 24.1 10.3 23.9 17.1 24.9 19.0 27.6 10.4 30.1 22.7 21.6 26.9 31.9 20.4 28.7 13.5 30.7 27.5 24.2 60.0 17.7 23.0 34.7 27.5 28.3 24.5 11.8 24.3 16.0 29.1 19.3 18.3 25.0 18.1 2.6 5.2 7.0 7.6 4.2 4.5 3.3 6.4 13.8 16.6 11.3 8.2 9.8 29.6 29.8 13.9 18.7 11.9 18.9 16.3 18.4 30.5 22.8 24.6 13.6 8.4 6.4 23.8 14.2 19.1 70.0 6.9 16.1 12.6 42.8 13.9 8.9 18.1 7.2 10.0 13.4 7.9 10.2 17.4 9.3 51.0 16.9 21.6 43.9 37.7 4.1 21.7 10.8 8.1 11.8 32.0 19.3 41.6 20.4 23.9 16.9 20.1 23.5 30.7 9.7 22.9 3.8 17.9 5.7 12.0 10.8 5.2 7.6 7.0 4.5 4.4 3.7 2.2 3.7 3.0 5.2 2.6 2.7 3.7 5.2 4.2 7.0 3.9 3.3 3.3 22.2 19.5 11.1 18.9 24.1 10.3 27.6 10.4 20.4 24.3 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294034 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 64.5" "Cell line enhanced" "Detected in many" "Karpas-707: 30.6;U-266/70: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 8.8;granulocytes: 5.1;monocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" 72000 Vesicles "Plasma membrane" "HPA036302: , HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.9 14.7 7.1 3.5 8.2 4.5 12.0 12.0 8.2 10.3 15.2 11.7 10.6 8.4 15.5 6.1 4.7 13.1 7.7 17.7 6.4 5.8 18.7 32.5 5.3 2.2 10.1 4.9 28.3 64.5 11.6 11.6 26.2 8.0 10.5 8.9 11.0 12.0 10.6 15.1 7.3 16.0 10.6 6.8 47.3 8.7 6.9 9.7 2.2 17.1 5.0 3.2 11.3 16.0 1.1 8.8 5.1 10.5 0.8 0.7 1.3 3.7 2.1 1.9 2.9 10.6 3.7 6.4 2.1 1.9 1.2 1.2 5.3 4.3 4.7 5.3 3.8 1.0 4.6 0.9 0.7 0.0 3.7 0.0 1.5 11.5 4.6 2.2 3.8 5.7 2.4 0.1 2.8 2.1 5.7 30.6 0.9 1.7 1.6 3.8 1.8 3.3 16.3 1.1 4.1 0.1 15.5 3.7 2.8 3.8 2.0 2.1 0.9 10.8 2.0 2.2 1.4 4.7 2.8 22.6 12.3 10.9 2.6 3.8 0.0 2.0 8.2 5.1 0.2 7.8 0.3 0.8 0.3 0.1 8.8 1.1 0.7 0.1 1.7 0.8 10.5 7.4 0.0 1.3 7.1 8.2 12.0 8.2 6.4 5.8 10.1 4.9 8.0 9.7 INSRR IRR ENSG00000027644 "Insulin receptor related receptor" P14616 1 156840063-156859018 "Enzymes, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.5;brain: 5.9;kidney: 8.3" "Group enriched" "Detected in some" 7 "SCLC-21H: 5.4;SH-SY5Y: 18.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA025285 Uncertain "HPA025285: AB_1851814" "unprognostic (1.19e-1)" "unprognostic (7.69e-2)" "unprognostic (2.42e-2)" "unprognostic (6.76e-4)" "unprognostic (1.51e-1)" "unprognostic (9.07e-3)" "unprognostic (5.57e-2)" "unprognostic (1.75e-1)" "unprognostic (6.17e-2)" "unprognostic (5.57e-2)" "unprognostic (2.20e-2)" "unprognostic (7.00e-2)" "unprognostic (4.22e-5)" "unprognostic (2.82e-1)" "unprognostic (9.55e-2)" "unprognostic (2.75e-3)" "unprognostic (3.66e-2)" 0.9 5.5 0.0 0.3 5.9 0.1 0.8 1.9 1.4 1.9 0.1 0.0 0.0 0.1 2.7 0.1 0.1 0.6 0.3 1.9 0.5 1.3 8.3 0.1 0.1 0.4 0.8 0.6 0.3 0.9 0.1 1.7 0.4 5.6 2.7 0.1 2.1 0.6 0.5 0.4 0.1 0.2 0.3 0.0 0.2 3.0 4.2 0.4 0.3 0.3 0.0 0.8 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 1.4 0.5 1.3 0.8 0.6 5.6 0.4 IP6K1 "IHPK1, KIAA0263" ENSG00000176095 "Inositol hexakisphosphate kinase 1" Q92551 3 49724294-49786542 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040825 Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA040825: AB_10960426" "unprognostic (6.18e-2)" "unprognostic (1.33e-1)" "unprognostic (3.58e-2)" "unprognostic (4.71e-2)" "unprognostic (1.99e-1)" "prognostic favourable (2.08e-4)" "unprognostic (9.97e-3)" "unprognostic (8.45e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "prognostic favourable (6.85e-4)" "unprognostic (1.29e-2)" "prognostic favourable (5.77e-5)" "unprognostic (8.75e-2)" "unprognostic (1.67e-1)" "unprognostic (9.24e-2)" "unprognostic (1.64e-2)" 14.2 17.5 23.5 12.9 26.9 12.1 15.8 38.6 40.4 17.7 16.1 20.7 16.1 13.6 21.4 14.5 19.6 20.0 14.7 13.7 23.8 23.5 16.3 15.9 16.9 16.3 17.9 18.3 30.2 21.9 30.3 16.7 18.3 21.2 14.3 13.2 18.6 18.3 21.1 9.0 18.2 12.7 19.5 16.9 16.9 13.7 27.3 14.8 22.3 17.1 8.4 14.4 16.3 15.6 6.8 4.1 24.0 4.8 6.9 9.7 6.0 12.3 15.0 17.6 20.6 18.4 14.2 14.2 16.5 17.4 27.1 23.8 19.4 12.9 10.8 10.7 18.2 9.2 24.8 14.9 15.4 21.6 19.7 24.4 23.0 13.1 20.3 14.9 17.1 16.5 18.6 29.2 17.7 22.6 15.9 12.7 13.3 11.0 18.1 15.6 18.9 25.0 11.5 12.5 21.6 17.5 18.9 9.5 19.0 21.0 13.7 18.9 11.0 22.0 20.2 15.2 15.3 20.8 19.1 15.5 20.8 11.5 13.9 17.3 15.5 2.5 4.8 8.2 8.7 3.9 8.8 4.6 8.0 9.6 4.1 6.8 9.7 9.5 24.0 6.9 4.8 2.9 8.2 6.0 23.5 26.9 38.6 40.4 23.8 23.5 17.9 18.3 21.2 14.8 IP6K2 IHPK2 ENSG00000068745 "Inositol hexakisphosphate kinase 2" Q9UHH9 3 48688003-48740353 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007532, HPA070811" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA007532: AB_1851542, HPA070811: " "prognostic favourable (1.25e-4)" "unprognostic (2.55e-2)" "unprognostic (8.86e-2)" "unprognostic (6.69e-3)" "unprognostic (1.01e-1)" "unprognostic (1.49e-2)" "unprognostic (1.76e-3)" "prognostic favourable (2.95e-4)" "unprognostic (6.57e-3)" "unprognostic (1.56e-1)" "unprognostic (1.92e-3)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.64e-1)" "unprognostic (3.50e-2)" "prognostic favourable (1.83e-4)" 18.3 31.1 40.4 20.0 55.9 51.7 28.2 74.1 37.3 29.5 32.5 23.7 34.0 36.9 34.6 56.1 30.0 28.1 24.0 19.0 30.7 19.2 32.4 24.3 18.4 22.5 35.4 27.6 33.9 28.1 23.5 42.3 20.7 29.4 34.9 41.9 22.2 28.3 32.1 19.1 50.0 31.6 21.1 28.3 25.5 27.6 26.0 37.4 31.7 35.7 21.6 19.5 24.1 34.0 27.3 22.8 50.7 25.7 27.9 35.1 19.0 8.7 17.2 35.7 25.1 20.1 25.2 25.8 16.8 18.9 19.3 22.4 14.2 23.6 15.6 13.8 15.6 23.0 17.8 25.1 18.0 18.3 15.7 17.8 53.2 30.4 16.3 16.8 17.4 23.9 36.6 26.1 21.6 26.6 13.3 19.6 22.3 19.5 36.0 23.1 27.4 31.9 15.1 11.8 17.0 26.2 42.2 22.3 33.7 36.3 24.7 17.8 23.9 28.5 18.9 21.0 20.9 13.1 16.5 18.1 21.4 21.9 19.1 19.7 18.3 50.7 22.5 38.5 29.7 21.6 26.5 27.3 25.8 27.7 21.7 25.7 24.2 24.9 35.3 27.9 25.7 22.8 35.1 19.0 40.4 55.9 74.1 37.3 30.7 19.2 35.4 27.6 29.4 37.4 IP6K3 "IHPK3, INSP6K3" ENSG00000161896 "Inositol hexakisphosphate kinase 3" Q96PC2 6 33721670-33746905 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 22.5;skeletal muscle: 87.9" "Cell line enhanced" "Detected in some" "HHSteC: 15.8;HSkMC: 5.7;LHCN-M2: 25.1;RH-30: 11.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 13.0;cerebral cortex: 6.2;midbrain: 22.5;pons and medulla: 7.7;thalamus: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA053644 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA053644: " "unprognostic (3.23e-2)" "unprognostic (2.87e-1)" "unprognostic (2.07e-5)" "unprognostic (1.07e-3)" "unprognostic (2.20e-1)" "unprognostic (5.10e-3)" "unprognostic (1.38e-1)" "unprognostic (1.75e-1)" "unprognostic (2.45e-1)" "unprognostic (2.47e-2)" "unprognostic (1.24e-2)" "unprognostic (2.94e-3)" "prognostic unfavourable (6.09e-4)" "unprognostic (1.63e-2)" "unprognostic (2.01e-1)" "unprognostic (2.66e-3)" "unprognostic (1.33e-1)" 2.2 1.0 2.1 0.8 13.0 0.5 0.9 0.6 6.2 1.2 2.2 11.8 1.4 0.8 1.6 1.4 5.2 1.3 0.6 10.0 3.2 1.3 4.7 7.7 2.0 0.6 22.5 1.1 0.6 0.7 0.5 0.5 3.8 7.7 2.8 1.0 1.2 1.4 1.8 87.9 0.5 1.1 1.8 9.2 1.4 0.9 0.6 15.2 0.0 9.9 8.1 0.5 1.5 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.5 0.1 0.2 0.2 1.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 5.7 0.8 0.1 0.4 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.1 0.0 0.0 11.1 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.1 13.0 0.6 6.2 3.2 1.3 22.5 1.1 7.7 15.2 IPMK ENSG00000151151 "Inositol polyphosphate multikinase" Q8NFU5 10 58191517-58267934 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 6.4" "Group enriched" "Detected in many" 4 "granulocytes: 6.4;monocytes: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037837, HPA057542" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA037837: AB_10670166, HPA057542: " "unprognostic (4.52e-2)" "unprognostic (3.29e-2)" "unprognostic (4.22e-3)" "unprognostic (6.85e-2)" "unprognostic (2.41e-2)" "unprognostic (1.99e-1)" "unprognostic (1.39e-3)" "unprognostic (2.10e-1)" "unprognostic (9.39e-2)" "unprognostic (2.23e-1)" "unprognostic (1.55e-1)" "unprognostic (8.56e-2)" "prognostic unfavourable (9.96e-7)" "unprognostic (1.79e-1)" "unprognostic (4.33e-1)" "unprognostic (1.27e-3)" "unprognostic (9.02e-3)" 12.2 4.1 5.4 6.8 5.6 2.8 6.7 8.7 5.6 5.9 19.4 3.5 2.1 9.5 3.2 5.6 10.8 3.8 8.6 7.4 5.2 5.5 5.3 21.3 11.0 13.8 4.9 3.3 4.8 6.0 22.5 6.1 13.8 4.3 4.4 7.5 4.8 6.4 4.4 9.8 9.0 28.1 4.9 6.0 14.1 4.4 2.9 3.8 11.7 5.9 4.9 5.9 10.4 12.3 0.7 1.0 6.4 2.1 0.4 0.9 0.4 14.6 3.7 5.6 5.4 5.4 6.4 4.8 3.9 8.3 3.3 6.7 7.5 9.4 11.7 7.9 4.6 4.5 4.7 5.1 10.7 5.3 3.5 2.9 3.8 7.2 3.3 4.5 6.7 7.0 4.7 5.6 11.4 7.1 1.9 6.0 5.8 3.6 6.2 8.8 3.5 3.6 0.4 12.0 5.4 6.2 3.8 3.9 6.7 5.0 13.4 3.9 11.2 5.5 6.1 3.6 7.0 7.6 4.9 13.0 7.6 9.3 6.9 4.8 1.4 2.3 1.5 3.3 0.4 1.6 0.4 0.7 0.4 0.2 1.0 0.4 0.9 0.3 6.4 0.4 2.1 0.4 0.1 0.4 5.4 5.6 8.7 5.6 5.2 5.5 4.9 3.3 4.3 3.8 IPPK "C9orf12, FLJ13163, INSP5K2, IP5K, IPK1" ENSG00000127080 "Inositol-pentakisphosphate 2-kinase" Q9H8X2 9 92613184-92670265 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020603 Uncertain Approved Cytosol Cytosol "HPA020603: AB_1851853" "unprognostic (3.51e-2)" "unprognostic (4.66e-2)" "unprognostic (6.26e-2)" "unprognostic (1.26e-1)" "unprognostic (3.63e-2)" "unprognostic (2.08e-1)" "unprognostic (4.88e-2)" "unprognostic (3.13e-2)" "unprognostic (4.40e-2)" "unprognostic (1.10e-1)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.26e-9)" "unprognostic (1.28e-2)" "unprognostic (4.23e-2)" "unprognostic (2.83e-1)" "prognostic unfavourable (1.28e-4)" 5.0 7.5 7.6 5.2 12.3 8.3 7.5 13.4 14.1 7.9 4.7 9.7 6.8 3.7 6.0 5.9 29.7 6.4 5.3 8.1 7.9 5.9 5.2 5.8 4.9 6.0 7.1 5.7 6.5 4.2 11.3 11.0 7.1 10.0 5.1 5.3 6.0 10.8 4.3 6.9 31.5 4.6 6.3 6.4 5.8 4.8 12.0 7.7 5.7 5.5 17.8 16.1 4.9 13.7 4.2 3.9 5.8 3.2 1.4 7.5 3.1 11.7 6.3 5.8 5.0 7.2 5.4 19.3 8.4 5.2 8.6 5.0 3.9 4.7 7.3 4.2 11.7 16.9 10.2 11.7 7.2 9.1 6.6 6.0 13.4 6.0 5.1 10.1 7.1 5.3 11.6 10.3 8.1 6.4 8.1 8.9 8.5 16.0 5.8 4.7 9.9 9.4 5.1 6.3 2.9 5.1 7.2 12.2 7.2 6.8 28.2 4.9 6.7 2.5 12.4 6.4 7.3 17.9 8.8 8.2 9.6 4.1 8.4 4.6 6.2 0.0 2.3 5.8 6.4 3.1 7.3 4.1 5.6 5.7 3.6 4.2 4.4 4.8 3.6 1.4 3.2 3.9 7.5 3.1 7.6 12.3 13.4 14.1 7.9 5.9 7.1 5.7 10.0 7.7 IRAK1 "IRAK, pelle" ENSG00000184216 "Interleukin 1 receptor associated kinase 1" P51617 X 154010500-154019980 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004461, HPA054476" Supported Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB004461: AB_2249106, HPA054476: " "unprognostic (4.46e-3)" "unprognostic (9.32e-2)" "unprognostic (1.71e-2)" "unprognostic (5.04e-3)" "unprognostic (7.09e-3)" "unprognostic (4.43e-3)" "prognostic unfavourable (3.03e-4)" "unprognostic (7.89e-3)" "unprognostic (3.36e-2)" "unprognostic (3.69e-2)" "unprognostic (1.95e-1)" "unprognostic (6.64e-2)" "prognostic unfavourable (2.06e-4)" "unprognostic (2.76e-3)" "unprognostic (2.36e-1)" "unprognostic (2.21e-3)" "unprognostic (3.04e-1)" 22.3 23.7 12.1 25.0 11.4 48.3 38.5 7.7 14.8 11.1 24.8 10.8 13.4 29.9 13.2 12.4 25.5 12.2 23.1 14.1 9.9 12.3 23.7 46.9 18.5 37.5 12.6 7.9 15.1 34.6 8.1 15.2 14.3 11.9 18.0 11.0 10.1 31.9 15.9 32.6 15.9 34.6 11.5 12.7 34.0 19.3 14.3 9.8 17.0 12.6 20.4 26.7 17.2 15.3 10.0 13.0 6.7 10.6 6.3 6.7 3.4 76.3 29.7 4.2 34.3 8.4 6.7 18.3 11.4 10.8 17.6 16.4 23.5 34.0 32.6 64.3 12.2 20.9 9.7 18.6 6.9 25.6 29.0 11.9 26.7 14.0 19.4 28.1 20.5 9.3 16.4 16.8 18.6 10.5 20.9 37.8 12.3 28.1 11.5 25.1 10.4 59.3 30.0 21.3 54.8 11.7 14.5 23.6 17.0 13.6 15.2 22.5 5.9 29.9 14.3 21.4 33.9 48.9 70.7 47.6 30.4 59.8 31.3 33.8 22.2 1.3 8.7 6.7 6.7 10.6 5.9 7.5 5.3 5.3 5.4 10.0 3.1 6.1 5.9 6.3 8.1 13.0 2.5 3.4 12.1 11.4 7.7 14.8 9.9 12.3 12.6 7.9 11.9 9.8 IRAK2 ENSG00000134070 "Interleukin 1 receptor associated kinase 2" O43187 3 10164865-10243743 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.7" "Cell line enhanced" "Detected in many" "BEWO: 17.7;BJ hTERT+: 18.4;CAPAN-2: 18.7;RT4: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013483, HPA050520" Uncertain Approved Vesicles Vesicles "CAB013483: , HPA050520: " "unprognostic (1.31e-1)" "unprognostic (2.04e-2)" "unprognostic (1.46e-2)" "unprognostic (4.61e-3)" "unprognostic (8.71e-2)" "unprognostic (9.55e-2)" "prognostic unfavourable (8.35e-4)" "unprognostic (1.89e-2)" "unprognostic (8.01e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (2.26e-4)" "unprognostic (2.24e-1)" "unprognostic (3.10e-2)" "unprognostic (7.22e-2)" "unprognostic (4.38e-2)" "unprognostic (3.91e-2)" "prognostic favourable (6.60e-5)" 12.1 5.8 3.6 8.6 5.9 28.7 5.4 4.5 7.0 3.3 4.0 12.2 2.3 3.3 3.5 2.6 8.4 2.4 6.8 2.7 3.6 5.2 4.3 15.4 12.7 5.3 10.4 3.7 1.9 3.2 2.4 1.8 3.5 7.8 6.4 3.1 2.1 4.8 3.4 19.6 6.2 6.7 3.4 6.1 5.9 5.2 1.7 8.6 3.9 4.1 2.7 16.7 14.3 7.2 5.0 1.3 2.5 1.2 8.4 7.9 2.5 1.4 4.0 0.1 0.5 4.4 3.7 17.7 1.5 18.4 2.5 2.4 1.9 18.7 0.0 0.5 2.2 0.4 0.4 4.7 3.4 1.1 1.3 0.4 0.9 5.1 2.1 0.0 0.6 2.2 0.8 9.2 12.1 5.1 0.9 5.7 3.0 0.0 0.0 0.9 0.1 3.9 0.8 0.0 0.3 5.5 25.5 0.2 0.1 1.7 0.1 0.2 0.4 0.8 5.3 5.7 0.5 3.5 3.6 1.9 5.6 1.0 12.3 2.4 1.0 0.2 1.2 0.1 7.5 0.7 7.9 5.0 2.2 4.1 1.3 4.5 1.6 3.9 2.5 8.4 0.2 0.1 0.9 2.5 3.6 5.9 4.5 7.0 3.6 5.2 10.4 3.7 7.8 8.6 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66188879-66254622 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.0" "Cell line enhanced" "Detected in some" "ASC diff: 14.7;ASC TERT1: 12.2;HEL: 12.6;HL-60: 16.7;NB-4: 13.3;THP-1: 20.2;U-937: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 5.6;classical monocyte: 13.1;intermediate monocyte: 13.2;myeloid DC: 6.2;neutrophil: 7.2;non-classical monocyte: 20.6" "Group enriched" "Detected in many" 12 "dendritic cells: 6.2;granulocytes: 7.2;monocytes: 20.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavourable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 21.8 3.7 2.1 10.6 3.6 58.0 13.4 1.0 2.4 8.7 6.5 2.3 5.5 1.7 6.2 8.6 4.9 7.0 7.6 16.0 2.9 2.1 3.6 2.9 22.1 25.6 4.6 0.3 5.9 2.7 1.3 17.9 6.1 3.7 7.0 3.0 5.5 6.0 5.5 5.5 3.3 4.9 6.4 5.9 25.3 6.2 5.1 2.8 1.0 4.9 4.5 5.4 9.5 11.4 0.4 6.2 7.2 20.6 0.9 0.3 3.6 0.0 0.0 0.2 0.0 14.7 12.2 0.0 1.6 0.0 0.9 1.3 0.0 1.2 0.0 0.8 3.0 0.0 1.8 0.0 0.7 0.0 0.0 12.6 0.7 0.0 7.7 16.7 2.3 7.7 0.0 0.7 0.0 4.3 0.0 0.0 0.5 0.0 0.0 13.3 0.7 0.0 0.0 3.6 0.0 0.1 1.8 0.1 0.0 6.5 0.0 0.7 0.0 20.2 4.6 0.0 0.0 0.0 0.0 0.5 0.1 1.2 0.0 14.7 0.0 5.6 13.1 2.2 0.0 13.2 0.0 0.0 0.0 0.0 6.2 0.4 0.0 0.0 7.2 0.9 20.6 0.0 0.3 3.6 2.1 3.6 1.0 2.4 2.9 2.1 4.6 0.3 3.7 2.8 IRAK4 NY-REN-64 ENSG00000198001 "Interleukin 1 receptor associated kinase 4" Q9NWZ3 12 43758944-43789543 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 32.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016685, CAB022077" Uncertain Approved Nucleoli,Microtubules,Cytosol Microtubules "Nucleoli, Cytosol" "CAB016685: AB_1618505, CAB022077: " "unprognostic (2.76e-2)" "unprognostic (5.63e-2)" "unprognostic (1.47e-2)" "prognostic favourable (3.46e-5)" "unprognostic (6.15e-2)" "unprognostic (3.50e-3)" "unprognostic (1.44e-2)" "unprognostic (8.49e-2)" "unprognostic (6.44e-3)" "unprognostic (7.50e-2)" "unprognostic (4.00e-3)" "unprognostic (6.29e-2)" "unprognostic (4.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "prognostic favourable (4.42e-5)" 18.0 9.4 5.1 15.0 10.4 10.3 11.3 3.7 6.0 10.3 12.2 9.1 12.5 10.2 13.0 14.1 15.0 9.4 10.8 7.6 6.7 5.2 13.3 11.8 12.0 24.0 13.2 3.9 9.3 20.1 9.1 16.1 14.0 9.8 10.5 10.0 11.9 11.9 15.1 4.1 15.2 15.0 11.8 13.0 25.0 12.3 7.1 11.7 30.3 17.0 7.7 18.9 11.1 10.7 5.1 5.8 16.9 6.0 8.8 7.7 4.7 5.3 3.9 2.8 3.7 10.1 17.0 4.0 7.5 5.3 6.0 5.5 3.3 5.1 9.1 7.4 6.2 4.4 3.1 4.8 8.6 13.0 2.9 8.7 3.0 2.1 5.8 12.0 10.7 9.0 7.8 7.6 4.4 8.8 8.0 6.8 16.4 2.9 10.4 6.8 1.0 4.6 6.9 3.4 4.8 4.6 5.1 2.0 1.9 3.6 4.7 3.6 5.9 10.7 7.8 7.4 1.4 9.0 5.1 8.4 10.8 7.9 7.6 32.4 4.0 16.9 4.6 9.4 7.4 5.4 7.7 4.0 6.1 6.3 4.5 5.1 5.5 5.9 9.3 8.8 6.0 5.8 7.5 4.7 5.1 10.4 3.7 6.0 6.7 5.2 13.2 3.9 9.8 11.7 IRF2BP1 "DKFZP434M154, IRF-2BP1" ENSG00000170604 "Interferon regulatory factor 2 binding protein 1" Q8IU81 19 45883607-45886170 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042164, HPA049480" Approved Supported Nucleoplasm Nucleoplasm "HPA042164: , HPA049480: " "unprognostic (5.90e-2)" "unprognostic (1.34e-1)" "unprognostic (8.86e-2)" "unprognostic (9.49e-2)" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (1.62e-1)" "unprognostic (1.67e-1)" "unprognostic (3.03e-1)" "unprognostic (1.01e-1)" "prognostic favourable (2.32e-4)" "unprognostic (2.60e-1)" "prognostic favourable (3.85e-5)" "unprognostic (1.33e-2)" "unprognostic (6.99e-2)" "unprognostic (2.66e-1)" "unprognostic (5.07e-3)" 14.2 11.9 12.2 9.0 14.1 6.7 8.7 23.1 26.2 12.7 11.2 12.6 10.6 14.4 15.3 8.1 8.2 12.4 12.6 10.8 11.8 11.7 12.0 14.8 10.0 9.5 13.2 12.8 20.3 18.5 12.4 15.6 8.6 12.5 13.5 4.8 12.6 19.6 15.2 33.4 13.4 12.4 9.3 8.7 15.6 16.4 8.0 12.8 17.4 13.7 8.0 8.6 12.0 8.7 2.7 2.0 1.4 1.7 2.4 3.6 1.6 8.2 12.6 3.1 6.9 2.7 1.7 5.1 6.1 3.5 4.9 4.3 4.7 3.9 6.7 4.6 3.1 7.8 2.2 2.3 1.4 8.4 21.9 6.7 3.6 5.9 5.4 6.9 6.3 2.3 3.1 2.5 1.8 3.0 10.5 5.3 1.8 6.4 14.0 37.8 5.8 11.3 16.1 3.6 5.7 3.4 4.6 9.3 16.0 6.4 8.5 7.7 7.0 12.9 4.3 4.2 8.6 3.2 8.6 14.6 16.1 3.9 5.7 6.6 6.1 0.0 1.2 0.4 2.8 1.7 2.8 2.7 2.5 2.3 1.1 2.3 3.6 2.2 1.4 2.4 0.7 2.0 2.3 1.6 12.2 14.1 23.1 26.2 11.8 11.7 13.2 12.8 12.5 12.8 ISPD "hCG_1745121, IspD, Nip" ENSG00000214960 "Isoprenoid synthase domain containing" A4D126 7 16087527-16421322 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 8.3;HEL: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 17 "basophil: 10.7" "Lineage enriched" "Detected in single" 22 "granulocytes: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043810, HPA053554" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA043810: AB_10964489, HPA053554: " "unprognostic (4.65e-3)" "unprognostic (5.92e-2)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "unprognostic (1.49e-2)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (7.07e-2)" "unprognostic (3.47e-2)" "unprognostic (3.39e-2)" "unprognostic (6.01e-2)" "unprognostic (2.07e-1)" "prognostic favourable (1.38e-11)" "unprognostic (4.01e-2)" "unprognostic (1.78e-4)" "unprognostic (6.26e-2)" "unprognostic (2.79e-1)" 3.0 3.8 4.2 1.9 4.5 2.6 3.0 7.7 7.7 3.7 2.9 3.9 3.4 1.8 4.7 2.4 2.0 2.8 3.2 7.1 4.4 4.5 7.0 10.0 2.9 1.5 4.7 3.9 2.7 3.9 3.6 5.7 8.0 4.6 3.5 3.0 5.7 5.5 10.1 4.5 2.6 1.8 3.7 4.9 1.4 10.2 3.9 2.4 1.1 2.6 2.4 1.4 3.2 3.7 0.3 0.4 10.7 0.1 0.4 0.3 0.0 0.3 2.3 1.2 1.8 1.0 1.5 8.3 1.8 1.2 1.6 1.3 2.6 2.2 0.0 4.0 2.6 3.0 1.4 0.0 2.9 1.0 1.4 11.5 1.4 0.6 1.3 0.9 1.4 2.7 1.2 1.3 0.2 1.2 2.7 0.2 4.1 0.5 1.1 1.0 2.2 0.3 0.0 1.8 0.1 2.7 0.8 2.0 1.3 1.3 2.4 2.5 1.7 2.6 1.3 2.3 2.1 0.3 2.2 0.2 0.0 0.0 1.9 2.7 2.8 10.7 0.1 0.4 0.3 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.3 0.2 0.6 0.4 0.0 0.4 0.0 0.0 4.2 4.5 7.7 7.7 4.4 4.5 4.7 3.9 4.6 2.4 ISYNA1 "Ino1, INOS, IPS" ENSG00000105655 "Inositol-3-phosphate synthase 1" Q9NPH2 19 18434388-18438301 "Enzymes, Predicted intracellular proteins" "Inositol biosynthesis, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 83.6" "Cell line enriched" "Detected in many" 4 "BEWO: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.0;NK-cells: 11.9;T-cells: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007931, HPA008232, CAB020720" Enhanced Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB020720: , HPA007931: AB_2667940, HPA008232: AB_2668018" "unprognostic (1.87e-2)" "unprognostic (1.86e-1)" "unprognostic (2.98e-2)" "unprognostic (3.16e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-2)" "unprognostic (2.49e-1)" "unprognostic (3.12e-1)" "unprognostic (1.74e-1)" "unprognostic (2.28e-2)" "unprognostic (2.73e-2)" "unprognostic (5.08e-2)" "prognostic unfavourable (9.23e-4)" "unprognostic (2.23e-2)" "unprognostic (9.26e-2)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" 7.9 8.4 7.1 3.0 5.7 4.5 7.1 2.7 6.7 9.9 3.5 10.0 44.2 3.4 13.9 12.3 4.5 20.0 6.5 8.0 5.7 7.4 12.7 4.1 4.7 3.8 4.1 4.1 31.6 25.5 7.7 12.6 44.2 16.2 9.5 1.3 19.3 8.8 34.4 8.2 3.4 3.9 3.0 2.3 10.5 3.7 83.6 3.5 3.0 5.6 3.8 3.3 5.9 7.8 4.0 1.9 0.9 0.2 11.9 8.5 4.9 2.7 8.4 20.1 5.9 0.1 0.0 101.5 1.3 0.2 0.1 0.0 4.8 5.1 0.0 6.9 0.6 7.2 0.6 0.0 0.0 7.5 23.1 10.1 0.5 15.5 2.1 0.1 0.2 1.6 0.1 0.5 0.1 1.2 20.6 0.4 0.0 16.2 0.7 0.7 10.5 6.8 13.9 0.0 4.7 1.7 0.0 6.2 15.5 0.3 1.9 10.2 13.7 1.1 3.9 0.1 0.2 0.1 0.3 3.2 1.4 0.6 0.6 0.4 3.5 0.9 0.1 0.0 7.6 0.2 5.9 4.0 7.4 6.7 0.7 2.3 6.1 8.5 0.8 11.9 0.1 1.9 5.2 4.9 7.1 5.7 2.7 6.7 5.7 7.4 4.1 4.1 16.2 3.5 ITCH AIP4 ENSG00000078747 "Itchy E3 ubiquitin protein ligase" Q96J02 20 34363235-34511393 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021126, HPA049032, CAB072824, CAB072825" Supported Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB072824: , CAB072825: , HPA021126: AB_1851941, HPA049032: " "unprognostic (2.51e-1)" "unprognostic (6.95e-2)" "unprognostic (1.25e-3)" "unprognostic (3.22e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (9.29e-3)" "unprognostic (1.94e-1)" "unprognostic (3.89e-3)" "unprognostic (1.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (1.30e-1)" "unprognostic (2.24e-1)" "unprognostic (3.23e-2)" "unprognostic (2.21e-1)" 20.7 16.7 18.9 15.4 26.9 20.5 17.5 19.8 26.7 23.9 18.2 37.9 15.2 16.9 18.4 15.1 35.9 14.5 14.5 17.9 20.4 15.9 21.1 46.5 18.5 16.8 29.2 16.5 19.3 17.1 21.6 26.3 26.9 29.0 17.5 20.4 16.7 20.1 18.4 24.0 19.2 20.3 19.8 30.4 17.3 17.3 34.8 32.3 22.3 22.7 13.0 23.6 19.6 21.0 7.3 11.4 19.6 6.2 6.2 11.4 2.7 20.0 13.2 13.5 9.7 14.9 21.3 16.2 16.3 18.7 20.4 20.0 37.2 30.9 9.8 15.8 20.8 25.4 20.5 32.9 24.9 7.4 6.6 28.4 11.2 22.2 15.6 11.6 12.9 10.8 16.8 17.2 27.0 15.3 16.1 17.0 15.9 10.0 17.0 6.2 6.5 15.7 14.3 28.5 22.6 12.1 34.8 8.3 6.1 30.5 11.9 18.3 14.3 10.5 14.8 24.4 14.7 15.9 12.0 13.5 14.1 14.3 15.1 7.5 14.3 3.6 5.8 6.1 10.8 6.2 11.4 7.3 3.8 5.7 4.5 6.9 3.3 4.9 19.6 6.2 3.8 11.4 4.8 2.7 18.9 26.9 19.8 26.7 20.4 15.9 29.2 16.5 29.0 32.3 ITPA "C20orf37, dJ794I6.3, HLC14-06-P" ENSG00000125877 "Inosine triphosphatase" Q9BY32 20 3208868-3223870 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022824, HPA073963" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" 69000 Cytosol "Nucleoplasm, Nuclear bodies" "HPA022824: AB_1851960, HPA073963: " "unprognostic (1.58e-2)" "unprognostic (1.98e-1)" "unprognostic (1.73e-1)" "unprognostic (3.57e-1)" "unprognostic (4.63e-2)" "unprognostic (1.53e-2)" "prognostic unfavourable (2.54e-5)" "unprognostic (1.11e-2)" "unprognostic (1.68e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-1)" "unprognostic (1.94e-2)" "unprognostic (8.34e-2)" "unprognostic (3.63e-1)" "unprognostic (1.24e-1)" "unprognostic (1.84e-1)" 17.7 27.5 18.6 24.7 21.2 20.4 17.7 10.2 22.7 21.3 21.4 18.3 20.6 22.9 18.1 17.3 31.0 26.6 19.6 25.9 18.1 13.5 22.9 20.3 22.7 30.6 20.5 24.1 16.5 43.8 17.6 10.2 17.0 16.2 14.6 16.8 13.2 19.9 21.5 19.5 23.4 19.0 16.3 16.3 20.6 19.3 16.7 19.5 15.2 24.9 29.0 24.1 14.6 17.7 19.3 30.7 11.3 31.0 24.7 24.1 18.2 33.1 26.2 13.0 13.4 8.6 12.7 8.6 15.0 21.0 19.8 17.4 21.0 30.9 14.3 13.8 13.8 28.9 17.8 22.6 13.9 9.3 26.6 35.8 10.9 31.8 16.3 15.3 12.2 12.1 17.3 18.7 11.6 15.1 24.5 9.9 17.8 15.2 18.0 44.4 21.7 26.5 17.3 18.1 37.5 27.1 10.5 19.7 23.2 11.9 41.7 27.6 17.3 25.6 10.6 22.3 12.4 14.6 31.8 14.7 18.4 27.0 10.4 28.4 24.2 11.3 25.7 8.8 20.7 31.0 18.0 19.3 18.9 21.8 30.7 17.8 14.2 17.2 1.4 24.7 21.9 28.3 24.1 18.2 18.6 21.2 10.2 22.7 18.1 13.5 20.5 24.1 16.2 19.5 ITPK1 ENSG00000100605 "Inositol-tetrakisphosphate 1-kinase" Q13572 14 92936914-93116320 "Enzymes, Predicted intracellular proteins" "Hydrolase, Isomerase, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 24.2" "Group enriched" "Detected in all" 5 "granulocytes: 24.2;monocytes: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055230 Approved Approved Mitochondria Mitochondria "HPA055230: " "unprognostic (1.93e-3)" "unprognostic (2.50e-1)" "unprognostic (2.15e-1)" "prognostic favourable (8.56e-4)" "unprognostic (4.27e-1)" "unprognostic (2.04e-2)" "unprognostic (6.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.24e-2)" "unprognostic (2.86e-2)" "unprognostic (8.14e-2)" "unprognostic (2.27e-1)" "unprognostic (1.37e-3)" "unprognostic (2.39e-1)" "unprognostic (2.02e-1)" "unprognostic (4.20e-1)" "unprognostic (7.25e-3)" 32.0 10.2 44.3 11.9 49.5 12.2 14.4 19.3 50.5 23.8 20.0 29.7 9.6 34.9 20.2 10.2 18.7 15.9 16.1 18.4 49.0 30.6 11.4 13.4 13.0 7.6 42.1 27.1 11.4 15.0 13.2 5.3 11.2 18.5 15.1 13.6 14.5 8.3 19.1 9.4 5.5 36.6 19.4 44.8 14.1 11.9 9.4 26.1 3.4 10.0 3.2 5.5 16.7 16.2 1.9 3.9 24.2 13.0 1.3 1.9 2.4 10.2 21.3 4.0 10.0 8.9 5.0 10.6 4.4 6.6 8.8 5.4 12.2 18.5 6.5 22.0 6.9 12.2 11.4 18.9 2.8 24.1 4.9 14.4 5.7 10.5 6.6 6.5 16.0 3.2 11.4 4.5 10.2 8.6 7.8 7.5 4.2 27.5 5.6 9.3 8.3 9.6 10.6 5.8 9.7 5.9 17.3 10.8 13.6 11.1 22.5 18.8 30.2 8.0 6.7 6.2 6.7 10.3 6.9 7.4 6.7 4.2 5.6 5.1 42.1 2.5 5.2 9.5 1.9 8.6 1.1 1.9 1.2 1.2 3.9 0.7 0.7 1.3 24.2 1.3 13.0 1.9 1.7 2.4 44.3 49.5 19.3 50.5 49.0 30.6 42.1 27.1 18.5 26.1 ITPKA "IP3-3KA, IP3KA" ENSG00000137825 "Inositol-trisphosphate 3-kinase A" P23677 15 41493393-41503551 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 28.8;intestine: 19.8;stomach 1: 10.7" "Cell line enhanced" "Detected in many" "Hep G2: 22.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 12.3;basal ganglia: 21.2;cerebral cortex: 28.8;hippocampal formation: 10.4;olfactory region: 8.2" "Cell type enriched" "Detected in single" 8 "MAIT T-cell: 4.7" "Lineage enriched" "Detected in single" 13 "T-cells: 4.7" "Group enriched" "Detected in many" 13 "amygdala: 120.1;basal ganglia: 97.6;cerebellum: 62.9;cerebral cortex: 164.4;hippocampal formation: 162.9" "Group enriched" "Detected in many" 7 "amygdala: 12.1;basal ganglia: 40.8;cerebral cortex: 32.2;hippocampal formation: 28.6" HPA040454 Enhanced Approved Approved Vesicles Vesicles "HPA040454: AB_10672897" "unprognostic (5.91e-2)" "unprognostic (2.16e-3)" "unprognostic (4.19e-1)" "unprognostic (3.57e-3)" "prognostic unfavourable (6.77e-4)" "unprognostic (2.25e-2)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "prognostic unfavourable (3.76e-9)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-3)" "unprognostic (2.10e-2)" 0.4 3.0 12.3 1.1 21.2 0.8 0.4 3.0 28.8 0.6 8.5 0.3 0.0 19.8 0.6 0.5 0.4 0.6 0.6 0.7 10.4 0.9 0.4 0.8 0.4 0.4 1.6 8.2 0.6 2.5 1.7 0.0 0.7 0.3 0.8 3.4 0.0 2.1 0.8 1.4 0.4 19.7 0.7 0.2 0.4 10.7 3.5 0.6 0.0 0.4 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.3 4.7 0.0 4.8 1.3 0.2 5.6 0.0 1.8 10.2 3.0 2.4 2.0 2.1 11.2 0.2 0.0 2.5 0.2 0.5 2.4 0.2 0.1 4.5 3.0 6.8 3.0 22.7 9.2 2.3 0.3 0.1 0.1 1.9 0.6 0.1 8.6 1.3 0.7 3.2 0.2 4.4 0.6 4.0 1.1 1.0 0.4 0.2 0.3 0.5 1.1 2.2 0.0 0.2 0.6 3.4 0.2 4.9 5.1 5.5 8.1 0.7 7.1 0.0 9.1 9.0 1.6 0.0 0.0 0.0 0.3 0.0 4.7 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 12.3 21.2 3.0 28.8 10.4 0.9 1.6 8.2 0.3 0.6 ITPKB "IP3-3KB, IP3KB" ENSG00000143772 "Inositol-trisphosphate 3-kinase B" P27987 1 226631690-226739323 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 63.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030273, HPA072923" Enhanced Approved Nucleoplasm Nucleoplasm "HPA030273: AB_10601127, HPA072923: " "unprognostic (4.54e-2)" "unprognostic (3.85e-2)" "unprognostic (8.41e-3)" "unprognostic (9.37e-3)" "unprognostic (1.53e-1)" "prognostic favourable (1.72e-5)" "unprognostic (1.24e-1)" "prognostic favourable (6.65e-4)" "unprognostic (2.29e-1)" "unprognostic (9.57e-2)" "unprognostic (1.41e-2)" "unprognostic (1.75e-2)" "unprognostic (3.23e-3)" "unprognostic (2.90e-2)" "unprognostic (7.46e-2)" "unprognostic (6.54e-3)" "unprognostic (7.87e-2)" 23.8 4.2 34.7 13.0 35.1 14.8 15.2 11.1 33.6 14.3 19.7 32.4 8.5 6.0 27.1 15.6 12.6 15.3 8.9 7.8 27.9 24.8 9.7 3.2 13.4 22.7 50.4 16.3 8.8 4.8 10.1 4.2 13.5 40.0 13.1 6.3 20.8 24.9 21.3 9.8 10.5 12.5 32.6 63.1 19.0 12.4 3.2 34.0 20.0 5.9 4.3 17.1 19.6 8.5 3.1 0.9 7.7 3.5 3.0 7.9 2.6 2.8 3.0 4.9 5.6 3.8 2.5 1.3 0.7 3.3 1.5 3.6 0.5 3.5 12.8 4.6 0.7 4.1 6.2 2.5 0.7 1.7 4.2 5.7 3.3 0.0 1.5 5.3 10.2 2.8 3.6 1.7 1.6 10.5 0.0 1.8 0.2 2.6 9.7 7.1 10.6 4.9 3.8 8.8 2.8 11.3 4.5 2.9 3.7 2.3 1.7 28.1 7.2 6.0 7.3 2.0 1.5 1.8 4.5 0.1 4.6 15.7 0.5 4.8 7.4 1.2 1.4 7.7 4.4 2.1 3.9 1.9 5.3 4.5 0.9 3.1 7.9 5.7 5.4 3.0 3.5 0.8 3.0 2.6 34.7 35.1 11.1 27.9 27.9 24.8 50.4 16.3 40.0 34.0 ITPKC "IP3-3KC, IP3KC" ENSG00000086544 "Inositol-trisphosphate 3-kinase C" Q96DU7 19 40717103-40740860 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050760, HPA053003" Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA050760: , HPA053003: " "unprognostic (4.27e-2)" "unprognostic (3.73e-2)" "unprognostic (8.31e-2)" "unprognostic (9.12e-3)" "unprognostic (1.10e-2)" "unprognostic (9.81e-2)" "unprognostic (6.06e-2)" "prognostic unfavourable (4.91e-4)" "unprognostic (1.48e-1)" "unprognostic (1.54e-3)" "unprognostic (1.84e-3)" "unprognostic (2.63e-1)" "unprognostic (2.59e-1)" "unprognostic (1.70e-1)" "unprognostic (2.86e-2)" "unprognostic (3.45e-2)" "unprognostic (3.32e-1)" 26.0 8.2 6.6 9.8 10.9 2.4 13.4 4.4 7.7 14.2 9.3 3.7 7.6 8.5 8.8 5.2 46.8 11.0 17.1 10.8 13.2 3.7 7.3 7.7 18.4 6.9 4.4 2.7 6.8 16.4 6.4 9.9 10.8 23.8 12.1 5.2 6.0 15.4 8.4 8.1 21.6 9.8 11.9 17.8 6.5 11.4 3.8 5.2 3.2 7.8 31.4 28.0 10.6 17.1 3.3 2.3 3.9 3.2 0.9 3.5 1.7 6.5 6.2 3.8 6.0 17.5 15.2 6.2 3.9 8.3 4.1 3.6 8.9 6.8 1.8 4.5 5.0 6.9 3.8 16.9 1.7 3.4 3.9 1.4 2.2 6.2 17.3 1.5 1.9 21.1 24.7 3.8 14.2 9.9 5.3 3.2 3.9 8.0 2.2 2.3 1.9 2.8 2.4 1.9 2.5 6.3 11.1 2.7 3.4 3.9 16.1 3.6 7.4 3.9 6.3 2.6 3.9 1.7 2.6 1.8 0.4 1.9 4.1 1.5 2.8 3.9 3.2 1.7 3.5 1.6 1.4 1.4 2.7 1.9 1.5 3.3 1.9 2.2 1.6 0.9 2.2 2.3 2.6 1.7 6.6 10.9 4.4 7.7 13.2 3.7 4.4 2.7 23.8 5.2 IVD ACAD2 ENSG00000128928 "Isovaleryl-CoA dehydrogenase" P26440 15 40405795-40435947 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041391, HPA044250" Enhanced Supported Nucleoplasm,Mitochondria 66000 Mitochondria Nucleoplasm "HPA041391: , HPA044250: " "unprognostic (9.30e-2)" "unprognostic (3.31e-1)" "unprognostic (1.36e-2)" "unprognostic (4.24e-2)" "unprognostic (7.53e-2)" "unprognostic (1.74e-1)" "prognostic favourable (1.95e-5)" "unprognostic (1.50e-2)" "unprognostic (2.53e-1)" "unprognostic (2.84e-2)" "unprognostic (4.08e-2)" "unprognostic (2.31e-1)" "prognostic favourable (2.91e-9)" "unprognostic (1.40e-1)" "unprognostic (3.40e-2)" "unprognostic (1.14e-1)" "unprognostic (5.46e-3)" 12.3 32.0 15.4 13.2 20.6 6.7 24.3 14.4 18.0 12.7 13.7 20.5 23.3 12.3 11.8 16.6 8.9 17.2 22.7 30.4 13.8 16.1 28.9 71.9 14.2 10.4 16.1 15.9 19.4 18.9 19.5 23.9 7.4 16.3 21.0 13.0 14.4 11.8 31.9 30.6 3.5 9.8 13.7 14.7 11.0 14.4 11.2 15.7 8.6 55.7 12.2 9.0 11.2 7.9 11.6 34.1 14.3 29.8 14.7 13.5 8.6 8.7 5.3 9.6 17.3 15.4 13.5 0.4 13.5 13.1 17.3 10.7 19.7 7.6 0.3 25.7 16.9 10.3 18.4 19.8 10.6 12.5 14.8 22.6 15.4 18.9 27.0 9.2 22.5 20.5 6.9 9.6 20.1 17.0 1.0 1.1 15.4 13.7 11.4 14.2 8.1 16.8 16.7 13.3 10.4 20.4 23.6 16.5 9.2 18.5 40.4 8.1 34.7 40.6 14.5 14.3 9.4 10.1 10.7 21.8 14.9 0.3 13.5 9.1 14.1 5.8 10.2 14.3 13.5 16.1 12.6 11.6 7.5 11.4 22.3 9.9 8.4 11.7 1.3 14.7 29.8 34.1 9.7 8.6 15.4 20.6 14.4 18.0 13.8 16.1 16.1 15.9 16.3 15.7 IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "thyroid gland: 212.3" "Group enriched" "Detected in some" 6 "CACO-2: 3.3;SK-BR-3: 8.2" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "neutrophil: 5.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 13 "hippocampal formation: 8.1;thalamus: 2.6" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" "Plasma membrane" "HPA059627: " "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favourable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" 0.1 0.1 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.1 8.2 0.1 0.1 3.6 0.1 0.3 0.1 0.1 6.7 0.1 0.1 0.1 5.4 6.8 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.5 0.1 1.2 0.0 0.3 0.0 0.1 0.2 13.5 0.0 0.1 0.1 0.3 0.1 0.0 0.0 212.3 0.0 0.1 0.1 0.1 1.4 1.0 5.9 1.3 2.3 0.7 2.3 0.2 0.0 0.2 0.3 0.1 0.9 0.5 0.0 0.0 0.1 0.0 3.3 0.6 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.3 0.5 0.8 0.3 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.0 0.5 0.0 0.4 0.3 0.2 0.3 0.2 0.2 0.0 0.8 0.4 0.2 0.0 8.2 0.0 0.8 0.1 0.2 0.2 0.2 0.3 0.0 0.3 0.1 0.1 0.5 0.3 0.2 3.3 1.3 0.7 0.7 1.1 0.5 0.6 0.6 0.5 0.1 1.4 0.6 0.7 5.9 2.3 0.5 1.0 0.5 2.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.0 JADE2 "JADE-2, KIAA0239, PHF15" ENSG00000043143 "Jade family PHD finger 2" Q9NQC1 5 134524312-134583230 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025959, HPA055789" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA025959: AB_1855289, HPA055789: " "unprognostic (8.98e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-2)" "unprognostic (2.14e-1)" "unprognostic (7.69e-2)" "unprognostic (5.56e-2)" "unprognostic (8.25e-2)" "prognostic unfavourable (4.42e-4)" "unprognostic (1.58e-2)" "unprognostic (3.49e-2)" "prognostic favourable (5.36e-6)" "unprognostic (3.73e-1)" "unprognostic (1.76e-3)" "unprognostic (2.68e-1)" "unprognostic (2.87e-2)" 15.6 19.8 16.7 16.1 22.0 9.7 13.9 22.8 21.7 16.0 13.4 15.3 9.2 12.7 13.9 8.4 11.8 20.6 13.2 13.4 17.8 14.5 14.8 4.7 15.0 25.8 30.8 16.0 28.4 14.0 30.9 14.4 8.5 20.1 12.8 8.2 16.4 15.0 16.9 12.0 11.5 17.8 13.0 16.8 22.9 12.9 8.1 30.8 13.0 20.6 6.0 19.2 20.0 22.7 7.3 2.0 6.8 3.0 3.1 6.2 2.4 28.1 20.1 0.6 0.8 7.0 8.5 9.2 5.1 13.4 9.4 11.1 15.2 21.9 31.0 11.4 6.6 6.0 3.6 26.9 4.7 18.7 1.4 7.3 14.0 4.1 7.0 8.0 1.1 5.7 13.1 11.4 14.4 7.1 4.5 11.7 5.7 10.1 13.7 7.2 6.6 10.5 12.3 0.6 12.1 8.8 7.8 4.3 2.8 12.6 0.4 18.0 5.5 9.9 9.9 6.6 6.0 18.7 12.7 5.4 22.5 28.7 10.3 14.3 9.3 6.8 1.2 4.4 6.2 1.1 6.0 7.3 5.7 5.6 2.0 5.5 5.6 5.6 1.3 3.1 3.0 1.2 5.8 2.4 16.7 22.0 22.8 21.7 17.8 14.5 30.8 16.0 20.1 30.8 JAK1 "JAK1A, JAK1B, JTK3" ENSG00000162434 "Janus kinase 1" P23458 1 64833229-64966504 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013088 Approved "CAB013088: " "prognostic favourable (9.63e-4)" "unprognostic (1.24e-1)" "prognostic favourable (2.81e-4)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (4.21e-2)" "unprognostic (1.53e-1)" "unprognostic (7.00e-3)" "unprognostic (8.40e-2)" "unprognostic (7.88e-3)" "unprognostic (1.66e-2)" "unprognostic (8.84e-2)" "prognostic favourable (2.67e-4)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "unprognostic (3.51e-1)" 46.7 20.4 15.5 31.1 16.5 21.2 56.6 24.3 20.4 27.3 27.1 16.3 16.5 13.8 28.2 22.0 27.0 20.7 27.7 27.3 15.3 16.5 31.4 38.3 36.5 61.4 15.6 14.1 33.3 29.1 28.3 39.8 22.9 25.1 26.0 22.2 18.1 19.8 21.3 45.1 29.7 29.3 30.7 16.3 52.7 20.9 17.3 15.0 62.7 29.0 17.9 42.5 37.2 29.3 20.2 15.4 34.9 17.1 68.1 27.5 25.8 10.9 14.4 6.0 0.6 69.4 39.3 7.8 17.2 25.4 14.3 16.9 4.7 6.1 16.7 13.4 30.5 6.2 4.0 13.3 20.4 22.1 6.4 22.7 7.5 10.2 25.6 8.7 15.8 34.5 18.5 21.6 22.6 44.6 8.2 17.9 15.8 6.3 4.7 5.8 4.1 8.6 6.8 17.3 6.1 36.9 19.4 4.2 12.7 23.6 11.1 10.1 23.5 5.4 40.4 17.2 7.7 38.9 9.1 11.2 5.1 13.3 16.0 11.5 7.7 31.2 10.9 31.5 22.8 15.2 27.5 20.2 22.0 25.7 15.4 16.1 24.3 20.7 34.9 68.1 17.1 10.5 26.5 25.8 15.5 16.5 24.3 20.4 15.3 16.5 15.6 14.1 25.1 15.0 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5128183 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "ASC diff: 18.9;HDLM-2: 26.7;HEL: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 40.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 40.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: , HPA043870: " "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 19.8 8.8 11.5 19.0 10.5 19.0 17.7 14.7 14.4 17.8 10.6 7.0 10.3 7.2 14.8 13.6 12.4 13.4 14.6 27.6 10.3 6.7 7.7 5.6 16.1 19.4 7.0 10.5 15.9 6.7 10.1 7.5 12.0 10.0 12.0 7.4 9.4 7.2 7.4 14.4 19.0 12.3 10.4 11.7 21.5 14.1 10.1 9.0 13.6 8.6 6.5 13.5 13.9 15.6 2.1 9.6 40.8 7.5 3.4 2.1 2.5 2.5 1.4 1.4 2.5 18.9 4.9 0.4 3.4 2.9 2.6 1.7 0.1 0.8 0.1 0.8 2.0 0.8 1.5 2.1 1.9 26.7 0.5 54.8 2.9 0.7 3.9 3.7 2.8 4.0 0.9 1.1 1.8 2.4 3.9 6.4 4.7 0.9 0.9 5.2 1.3 1.7 1.9 2.7 0.7 2.0 1.3 1.6 0.9 1.0 1.5 1.0 0.7 6.5 5.0 4.0 1.3 4.1 2.4 1.2 2.2 0.5 5.2 1.8 2.0 40.8 7.5 13.4 2.1 7.3 1.7 2.1 1.6 1.2 9.6 1.9 0.9 1.1 7.1 3.4 5.8 3.6 1.6 2.5 11.5 10.5 14.7 14.4 10.3 6.7 7.0 10.5 10.0 9.0 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 68.3" "Cell line enhanced" "Detected in some" "HDLM-2: 20.1;HEL: 9.0;HMC-1: 9.2;Karpas-707: 23.5;U-266/70: 9.1;U-266/84: 13.5;U-937: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA070314: " "unprognostic (5.59e-3)" "prognostic favourable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavourable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.8 1.7 4.0 24.5 8.5 12.0 2.7 2.4 3.1 1.9 2.3 1.0 0.0 2.2 1.7 2.0 2.5 3.5 3.6 4.3 2.7 2.8 3.8 2.0 8.4 68.3 7.5 0.0 11.0 2.0 0.4 2.3 4.1 5.3 3.0 2.4 1.6 6.1 1.5 0.7 1.3 9.5 2.5 8.4 36.1 3.2 1.8 5.8 20.9 3.4 1.7 28.8 5.3 2.4 7.4 4.5 16.9 9.6 8.4 15.0 6.8 0.1 0.3 0.3 1.0 0.4 1.4 0.2 0.5 0.0 0.0 0.1 0.0 0.9 0.4 1.9 0.4 0.1 0.0 0.2 0.0 20.1 0.0 9.0 0.0 0.8 0.7 0.0 9.2 5.0 0.2 0.0 0.0 0.2 0.0 23.5 0.0 0.4 3.6 0.0 0.1 0.7 4.6 0.0 0.4 0.5 0.0 0.0 0.3 0.1 0.2 0.0 2.0 1.3 0.4 0.0 0.4 0.0 0.0 9.1 13.5 2.5 0.1 13.7 0.2 1.2 4.9 0.2 12.6 9.6 14.5 6.5 15.0 13.1 4.5 7.4 14.9 13.0 16.9 8.4 8.8 3.7 11.8 6.8 4.0 8.5 2.4 3.1 2.7 2.8 7.5 0.0 5.3 5.8 JOSD1 KIAA0063 ENSG00000100221 "Josephin domain containing 1" Q15040 22 38685543-38701556 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001168 Uncertain "HPA001168: AB_1079162" "unprognostic (6.50e-2)" "unprognostic (1.06e-2)" "unprognostic (3.42e-3)" "unprognostic (5.67e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (4.50e-4)" "unprognostic (1.65e-2)" "unprognostic (5.10e-2)" "unprognostic (1.39e-1)" "unprognostic (3.23e-3)" "unprognostic (2.46e-1)" "unprognostic (1.83e-3)" "unprognostic (1.06e-1)" "unprognostic (4.41e-1)" "unprognostic (2.88e-2)" "unprognostic (4.41e-1)" 20.4 16.8 17.5 19.9 18.3 55.8 26.0 23.2 30.5 19.0 34.6 11.0 16.2 19.9 19.1 20.1 20.8 18.6 29.9 20.8 16.9 14.2 13.1 16.0 22.6 18.8 14.2 20.7 35.5 18.8 14.7 19.5 16.5 13.9 16.2 28.8 12.5 15.0 27.7 16.5 17.2 45.2 20.8 15.0 16.5 16.8 13.7 8.1 16.4 16.1 20.9 17.2 23.6 18.6 3.3 2.5 7.2 5.6 4.1 7.6 2.5 25.9 9.3 13.7 17.7 17.6 21.6 10.4 20.0 23.9 26.1 27.4 15.4 13.2 24.9 10.4 20.0 16.8 18.9 17.7 21.1 26.6 12.6 13.2 22.4 13.1 30.0 23.6 13.0 18.7 26.5 24.6 42.3 30.8 11.8 26.5 19.1 11.0 10.2 9.7 5.2 10.6 18.5 20.1 10.4 14.1 13.4 12.7 6.8 23.0 11.4 20.5 11.4 6.9 26.7 15.6 19.1 20.1 12.1 29.4 25.4 20.3 20.7 12.7 14.4 1.8 3.5 3.7 5.3 5.6 3.8 3.3 4.5 6.9 2.5 3.2 4.9 7.6 7.2 4.1 3.0 2.1 5.8 2.5 17.5 18.3 23.2 30.5 16.9 14.2 14.2 20.7 13.9 8.1 KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124080023-124726325 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.2;retina: 31.2" "Cell line enhanced" "Detected in many" "CACO-2: 32.1;HEL: 19.6;SH-SY5Y: 9.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 4.3" "Lineage enriched" "Detected in single" 5 "T-cells: 4.3" "Low region specificity" "Detected in many" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol 110000 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" 5.5 4.3 12.7 2.4 14.1 0.6 4.2 1.8 35.2 4.0 3.8 3.7 0.5 2.7 5.6 2.3 9.6 4.2 3.1 12.1 17.6 3.9 2.6 7.3 2.9 1.1 4.1 15.8 2.3 11.9 2.5 14.4 6.8 9.4 3.1 2.1 31.2 2.2 5.4 23.5 1.5 7.2 6.4 3.6 8.0 11.5 2.2 2.4 0.0 5.3 6.7 3.1 2.9 4.1 0.1 0.0 0.9 0.0 0.1 4.3 1.2 0.3 0.6 3.6 0.7 0.5 0.1 4.6 1.4 0.8 1.4 0.6 32.1 2.5 0.1 0.4 3.6 0.2 0.8 0.0 1.1 0.0 0.3 19.6 0.3 4.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.6 4.5 0.1 0.4 2.3 0.0 0.0 2.0 3.1 1.0 1.6 0.0 0.1 0.3 1.2 9.2 0.4 0.3 0.3 0.7 0.1 8.1 4.1 1.6 0.6 0.6 0.0 0.3 0.0 0.5 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.3 0.0 0.0 2.4 0.7 0.9 0.1 0.0 0.0 4.3 1.2 12.7 14.1 1.8 35.2 17.6 3.9 4.1 15.8 9.4 2.4 KARS "DFNB89, KARS1, KARS2" ENSG00000065427 "Lysyl-tRNA synthetase" Q15046 16 75627474-75648643 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease mutation, Neurodegeneration, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041345, HPA041550" Enhanced Supported Cytosol "Intracellular and membrane" Cytosol "HPA041345: AB_10795589, HPA041550: AB_10794520" "unprognostic (1.56e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-2)" "unprognostic (1.02e-2)" "unprognostic (5.39e-2)" "prognostic unfavourable (8.84e-6)" "unprognostic (6.24e-3)" "unprognostic (8.97e-3)" "unprognostic (1.18e-1)" "unprognostic (9.11e-3)" "unprognostic (8.71e-3)" "unprognostic (8.46e-2)" "unprognostic (7.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.03e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" 25.4 21.1 19.2 29.2 22.0 24.6 28.0 17.5 19.5 26.3 28.3 15.2 28.1 20.6 23.4 26.7 35.8 24.1 27.5 49.6 16.3 18.6 31.7 47.1 25.8 26.6 18.8 16.2 34.9 62.6 28.5 22.4 30.4 19.6 30.7 29.7 20.1 31.7 23.2 80.0 26.6 32.3 28.4 17.1 37.3 26.3 33.6 14.5 41.3 34.4 43.6 34.7 38.6 33.4 32.8 39.0 35.5 44.2 35.0 62.4 39.5 26.7 31.3 22.9 31.5 24.6 24.9 45.1 22.7 27.9 50.0 37.8 55.3 35.3 48.4 25.1 30.2 38.6 46.1 41.5 54.7 14.1 23.7 26.5 27.4 57.2 45.0 39.9 29.9 29.2 29.8 44.2 72.0 40.7 44.2 11.6 37.7 61.9 41.0 42.7 48.4 23.1 54.0 20.5 59.0 40.0 22.8 34.5 28.0 57.0 20.9 25.3 28.2 37.8 22.4 27.7 28.6 21.1 32.4 24.9 28.5 115.3 24.2 34.1 33.7 20.9 31.5 35.5 34.1 44.2 62.4 32.8 42.3 40.2 39.0 27.6 40.1 36.1 7.2 35.0 43.2 24.6 43.5 39.5 19.2 22.0 17.5 19.5 16.3 18.6 18.8 16.2 19.6 14.5 KAT2A "GCN5, GCN5L2, PCAF-b" ENSG00000108773 "Lysine acetyltransferase 2A" Q92830 17 42113108-42121358 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048958 Uncertain "HPA048958: " "unprognostic (1.71e-1)" "unprognostic (9.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.31e-1)" "unprognostic (3.41e-1)" "unprognostic (9.07e-2)" "unprognostic (1.91e-3)" "unprognostic (3.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "prognostic favourable (3.57e-4)" "unprognostic (2.78e-2)" "prognostic unfavourable (1.41e-8)" "unprognostic (3.97e-2)" "unprognostic (2.90e-1)" "unprognostic (1.89e-1)" "unprognostic (2.29e-3)" 16.9 15.9 30.2 13.6 28.6 8.6 14.0 24.0 42.0 11.2 11.9 10.9 13.1 14.9 13.9 8.9 11.4 14.2 11.8 7.6 27.8 11.5 10.0 11.8 7.2 11.2 27.6 18.0 23.5 16.5 14.8 11.9 10.7 26.0 12.9 9.6 6.0 17.3 14.5 20.1 19.9 13.4 9.7 13.9 15.6 13.0 7.8 29.7 5.3 11.7 6.4 10.4 11.2 21.7 2.0 1.6 0.1 0.4 0.6 2.7 0.8 11.0 21.4 3.2 11.8 4.5 3.7 14.0 7.2 3.9 16.1 8.0 14.4 9.1 21.8 18.3 5.5 16.6 13.0 11.5 5.7 12.1 26.9 5.4 13.2 13.0 4.7 14.4 14.5 4.3 9.8 9.0 5.7 6.4 13.6 4.2 4.2 11.9 34.4 10.6 6.8 0.0 8.2 6.3 14.4 4.3 11.2 15.3 6.7 7.7 17.0 5.9 12.6 6.9 4.9 8.2 8.3 11.8 12.8 11.2 10.7 12.1 5.9 12.5 4.5 0.0 0.4 0.0 0.8 0.0 1.7 2.0 1.9 2.4 1.6 1.6 2.7 0.7 0.1 0.6 0.1 0.4 0.3 0.8 30.2 28.6 24.0 42.0 27.8 11.5 27.6 18.0 26.0 29.7 KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040023-20154404 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002470, CAB004526" Supported Supported Nucleoplasm,Centrosome Nucleoplasm Centrosome "CAB004526: AB_2128417, HPA002470: " "unprognostic (2.91e-2)" "unprognostic (6.85e-3)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (2.66e-2)" "unprognostic (3.01e-3)" "unprognostic (2.44e-1)" "unprognostic (3.83e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-3)" "unprognostic (7.13e-2)" "unprognostic (7.03e-2)" "unprognostic (2.26e-2)" "unprognostic (1.59e-1)" "unprognostic (5.16e-2)" "unprognostic (4.63e-2)" 10.6 6.6 30.1 9.4 27.5 24.9 6.8 22.0 20.1 10.2 9.4 27.6 7.9 10.9 7.8 5.4 17.3 7.7 8.0 21.9 24.7 18.0 10.8 24.0 10.1 12.7 26.8 15.9 18.2 11.6 38.1 8.7 8.5 24.2 9.5 8.1 10.7 20.9 9.2 33.4 8.9 13.0 8.7 21.4 11.7 9.0 1.8 31.1 8.7 10.0 7.4 12.0 8.7 11.0 2.1 2.7 5.5 1.5 1.1 4.8 0.8 1.5 3.9 2.2 3.6 9.0 8.4 5.1 5.0 7.4 5.3 7.8 1.1 2.6 13.4 2.1 9.4 1.1 5.4 1.6 4.5 12.2 5.1 11.8 6.2 0.4 4.2 1.8 15.3 3.6 2.9 4.6 3.0 5.0 7.5 19.0 7.5 1.8 3.8 3.5 0.9 3.9 5.1 4.1 2.8 7.2 8.0 1.1 2.4 2.8 4.5 17.0 4.7 8.0 4.8 9.0 3.6 3.3 5.7 7.3 15.1 3.2 8.2 7.8 18.9 1.3 1.1 2.8 3.6 1.5 3.4 1.0 3.1 2.5 0.9 2.1 1.1 2.1 5.5 1.1 1.1 2.7 4.8 0.8 30.1 27.5 22.0 20.1 24.7 18.0 26.8 15.9 24.2 31.1 KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Enzymes, Predicted intracellular proteins, Transcription factors" "Growth regulation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016953 Approved Supported Nucleoplasm Nucleoplasm "HPA016953: AB_1851277" "unprognostic (2.20e-1)" "unprognostic (3.58e-1)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (7.16e-2)" "unprognostic (1.29e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-1)" "unprognostic (2.74e-1)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "prognostic favourable (1.10e-13)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.54e-2)" 18.5 19.5 21.2 16.0 27.4 34.3 21.6 29.4 37.1 22.1 24.1 28.2 22.3 16.5 30.1 24.8 21.2 32.9 24.5 21.1 18.3 19.2 22.6 16.1 20.8 18.3 19.0 25.7 29.5 23.2 38.8 22.0 32.7 24.6 21.2 19.4 29.3 23.6 27.5 24.6 27.6 19.2 25.2 20.1 22.0 21.9 30.7 22.8 26.9 26.5 19.1 22.1 24.4 22.0 25.0 24.0 40.4 23.6 24.8 28.6 23.3 19.1 23.4 21.3 16.2 16.9 17.9 22.4 13.9 22.7 23.3 20.3 17.0 22.9 17.6 19.9 24.3 16.2 26.5 23.3 14.1 22.9 17.0 25.8 19.3 20.1 24.3 28.1 31.0 19.0 26.1 15.3 31.4 14.6 26.6 27.6 22.0 34.8 23.8 32.9 18.6 15.1 19.6 14.1 32.2 21.3 29.1 19.9 20.9 13.2 25.0 26.5 24.5 18.2 18.7 18.9 16.7 14.9 14.9 21.2 21.8 25.9 16.3 13.8 15.4 23.4 23.6 40.4 25.7 22.3 22.1 21.1 22.5 25.5 24.0 25.0 28.6 23.3 26.1 24.8 23.3 14.5 21.5 23.3 21.2 27.4 29.4 37.1 18.3 19.2 19.0 25.7 24.6 22.8 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051990 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Approved "Nucleoli,Nuclear speckles,Cytosol" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: , HPA065052: " "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 20.8 10.9 15.3 19.8 20.3 36.8 22.6 29.9 18.7 19.7 14.6 19.4 14.4 10.7 20.6 12.1 16.9 16.5 14.3 13.0 15.5 11.5 12.3 13.6 26.9 28.2 23.2 10.3 27.2 13.1 26.8 22.3 20.9 15.7 14.1 12.0 12.8 15.1 17.0 21.0 25.5 18.0 25.0 22.9 20.4 14.0 14.1 21.7 30.4 17.9 14.3 20.1 16.9 24.2 4.7 1.8 10.9 1.6 3.1 3.9 1.4 12.9 10.6 17.5 11.1 9.8 11.2 5.9 8.7 11.3 10.8 8.4 6.7 6.2 19.2 8.7 8.5 8.3 13.6 8.2 12.7 9.9 7.9 27.6 6.6 5.0 7.4 14.5 12.7 9.3 9.4 10.0 12.4 10.3 23.1 12.2 9.8 5.7 29.5 4.6 6.7 4.2 23.6 19.6 6.1 5.3 14.9 10.9 9.4 10.1 6.8 7.0 15.6 6.4 12.0 13.3 9.4 11.8 9.3 10.0 16.1 20.8 7.1 6.6 11.5 3.5 1.6 2.8 3.5 1.2 3.9 2.4 2.6 3.3 1.0 4.7 3.6 2.9 10.9 3.1 1.2 1.8 3.5 1.4 15.3 20.3 29.9 18.7 15.5 11.5 23.2 10.3 15.7 21.7 KAT6B "Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B" ENSG00000156650 "Lysine acetyltransferase 6B" Q8WYB5 10 74825582-75032622 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "PC-3: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006104 Supported Approved "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA006104: AB_1079445" "unprognostic (4.17e-1)" "unprognostic (1.98e-1)" "unprognostic (1.82e-1)" "unprognostic (2.32e-2)" "unprognostic (7.83e-2)" "unprognostic (2.85e-2)" "unprognostic (3.56e-1)" "unprognostic (2.62e-1)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (9.47e-2)" "unprognostic (8.78e-2)" "prognostic favourable (4.82e-4)" "unprognostic (2.52e-1)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (3.15e-1)" 11.6 9.5 11.1 13.2 11.9 15.1 12.4 19.0 11.6 16.7 12.2 13.3 15.3 7.2 25.1 13.0 12.0 13.2 12.0 10.0 10.6 9.5 9.0 7.3 9.2 9.0 9.0 9.9 24.6 13.3 24.8 31.1 9.4 8.9 13.5 9.6 10.1 17.9 12.0 15.3 10.6 11.3 16.2 9.3 10.4 13.0 12.8 12.1 26.6 13.0 8.9 12.5 14.3 12.7 3.2 1.9 1.6 1.1 5.3 3.7 1.5 3.9 4.1 7.4 6.2 5.8 8.6 3.6 3.5 6.9 3.0 3.3 2.7 4.6 8.4 1.9 6.4 3.1 3.9 3.0 4.9 3.5 5.7 3.1 3.3 3.8 4.4 7.3 2.1 5.6 5.0 4.1 6.6 3.4 3.3 7.3 3.8 4.2 7.0 3.4 4.1 22.7 11.0 3.8 1.8 2.2 2.0 3.7 6.1 3.6 6.5 3.2 3.7 2.9 4.2 4.2 5.0 2.8 3.3 5.4 6.2 5.6 4.6 7.8 0.9 0.7 1.1 1.6 3.2 0.9 3.4 2.4 2.4 2.7 1.2 3.2 3.7 3.4 0.9 5.3 0.8 1.9 2.4 1.5 11.1 11.9 19.0 11.6 10.6 9.5 9.0 9.9 8.9 12.1 KAT7 "HBO1, HBOA, MYST2, ZC2HC7" ENSG00000136504 "Lysine acetyltransferase 7" O95251 17 49788555-49835030 "Enzymes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044470, HPA071116" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA044470: AB_10965785, HPA071116: " "unprognostic (1.30e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-3)" "unprognostic (2.20e-2)" "unprognostic (7.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (1.36e-1)" "unprognostic (6.26e-2)" "unprognostic (1.44e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-3)" "unprognostic (2.75e-1)" "unprognostic (5.03e-2)" "unprognostic (6.23e-2)" "unprognostic (7.68e-2)" 15.8 14.3 16.9 16.2 25.9 44.4 17.5 37.0 35.0 19.5 17.3 23.8 17.9 13.1 27.3 18.6 18.8 19.5 14.6 25.3 16.8 21.8 18.7 11.3 13.9 15.3 17.0 23.6 21.9 13.6 44.4 19.8 19.8 21.9 20.4 14.9 20.8 18.9 23.3 31.7 22.7 14.7 21.8 17.9 15.8 15.5 63.7 19.1 25.9 28.6 14.5 20.6 22.7 17.4 13.0 12.7 15.2 11.4 20.6 20.7 14.2 13.0 18.4 17.8 12.5 8.4 11.2 21.6 11.4 13.3 20.5 14.7 28.4 9.3 15.0 18.5 12.1 11.5 17.0 11.9 24.2 16.3 16.8 17.8 13.4 11.8 12.6 18.2 14.8 10.6 11.9 18.4 23.0 15.1 19.7 14.9 19.1 19.9 25.8 13.1 44.3 16.1 16.3 28.5 12.9 9.6 14.8 19.4 16.5 11.6 7.0 10.7 25.6 16.1 9.0 26.0 14.1 11.3 14.7 21.9 23.9 17.6 11.8 10.9 16.2 15.2 11.0 15.1 16.9 8.9 20.7 13.0 16.3 17.1 12.7 12.2 20.6 16.2 13.1 20.6 11.4 6.6 14.3 14.2 16.9 25.9 37.0 35.0 16.8 21.8 17.0 23.6 21.9 19.1 KAT8 "FLJ14040, hMOF, MOF, MYST1, ZC2HC8" ENSG00000103510 "Lysine acetyltransferase 8" Q9H7Z6 16 31115754-31131393 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 17.8;neutrophil: 17.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066324 Supported Nucleoplasm Nucleoplasm "HPA066324: " "unprognostic (8.58e-2)" "unprognostic (9.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "unprognostic (8.59e-2)" "unprognostic (1.06e-1)" "unprognostic (3.22e-1)" "prognostic favourable (6.34e-4)" "unprognostic (3.13e-2)" "unprognostic (3.05e-1)" "unprognostic (5.50e-2)" "unprognostic (9.77e-2)" "unprognostic (7.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.29e-1)" "unprognostic (5.00e-1)" "unprognostic (1.41e-1)" 18.4 21.7 22.7 29.4 23.6 26.6 29.7 48.9 30.8 28.0 24.8 18.3 27.5 15.7 29.8 48.3 16.7 35.0 28.2 32.7 23.0 21.2 20.8 18.9 26.3 29.0 20.2 21.0 52.8 31.4 38.0 22.2 31.5 16.8 21.2 17.7 22.1 35.1 26.2 39.8 22.1 19.7 25.9 20.5 27.4 18.6 27.3 18.4 30.2 31.7 22.6 22.2 20.2 26.6 2.1 4.1 17.8 4.6 1.7 2.9 1.9 7.6 11.8 14.8 4.4 17.6 13.2 15.2 6.8 13.1 11.0 12.1 5.9 16.7 18.1 10.8 8.5 9.1 23.6 11.5 10.9 15.1 16.0 7.8 8.7 18.7 15.8 12.9 14.2 12.4 23.1 8.2 23.8 10.5 20.8 14.9 5.6 22.3 19.9 24.4 16.7 7.2 32.1 12.1 21.2 8.9 4.6 15.6 15.8 4.1 11.5 5.8 12.5 21.5 6.2 4.7 9.9 5.2 4.9 14.2 14.3 10.2 7.1 17.3 7.0 3.9 4.4 17.8 1.9 2.4 2.4 2.1 2.2 2.6 4.1 1.8 2.9 2.1 17.4 1.7 4.6 1.4 1.3 1.9 22.7 23.6 48.9 30.8 23.0 21.2 20.2 21.0 16.8 18.4 KATNA1 ENSG00000186625 "Katanin catalytic subunit A1" O75449 6 149594873-149648972 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036207 Approved Supported "Nucleoplasm,Centriolar satellite" "Centriolar satellite" Nucleoplasm "HPA036207: AB_10672238" "unprognostic (1.57e-1)" "unprognostic (2.41e-2)" "unprognostic (2.95e-2)" "unprognostic (3.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "prognostic unfavourable (3.57e-7)" "unprognostic (9.78e-2)" "unprognostic (8.89e-2)" "unprognostic (7.40e-2)" "unprognostic (2.70e-2)" "unprognostic (4.50e-2)" "unprognostic (3.92e-2)" "unprognostic (2.10e-1)" "unprognostic (3.37e-1)" "unprognostic (1.74e-3)" "unprognostic (8.85e-2)" 12.5 7.8 9.3 11.9 9.8 14.2 11.7 13.0 9.5 13.8 12.1 15.0 6.0 7.6 15.3 10.3 12.5 10.9 10.1 11.3 9.1 6.7 13.7 8.4 10.8 11.8 10.4 7.9 18.7 9.6 5.7 12.1 11.0 15.0 12.7 9.5 17.5 10.1 10.5 21.2 12.0 10.8 12.4 8.9 12.2 10.4 36.7 12.0 22.5 13.9 10.3 14.0 15.1 12.7 19.6 19.4 23.5 20.8 12.7 24.2 14.9 11.3 4.1 9.3 20.4 11.3 18.1 14.5 14.2 12.1 15.1 20.0 9.8 6.0 15.8 8.3 14.2 9.0 18.3 9.4 19.7 14.5 15.5 21.0 8.7 13.5 15.6 29.4 7.9 11.4 11.2 17.3 13.7 13.8 21.8 11.6 13.3 15.7 20.1 19.2 9.2 6.9 13.9 17.1 7.7 10.7 6.4 7.6 10.7 26.0 7.5 10.0 7.6 28.7 11.8 7.9 12.0 20.7 16.4 10.8 9.9 21.8 10.4 21.0 12.8 23.5 15.2 21.0 19.9 20.8 17.5 19.6 20.2 20.0 19.4 14.2 17.2 17.3 7.0 12.7 18.0 16.7 24.2 14.9 9.3 9.8 13.0 9.5 9.1 6.7 10.4 7.9 15.0 12.0 KATNAL1 MGC2599 ENSG00000102781 "Katanin catalytic subunit A1 like 1" Q9BW62 13 30202630-30307484 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046205 Uncertain Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA046205: AB_10965325" "unprognostic (3.34e-1)" "unprognostic (6.44e-3)" "unprognostic (2.08e-2)" "unprognostic (6.91e-2)" "unprognostic (2.53e-1)" "unprognostic (1.52e-1)" "unprognostic (1.57e-2)" "unprognostic (2.84e-2)" "unprognostic (3.43e-1)" "unprognostic (4.68e-3)" "unprognostic (4.54e-2)" "unprognostic (2.17e-2)" "unprognostic (1.84e-3)" "unprognostic (7.41e-2)" "unprognostic (6.42e-2)" "unprognostic (5.12e-2)" "unprognostic (1.83e-3)" 11.0 5.7 12.2 6.4 12.5 7.6 12.0 11.0 14.4 14.1 11.4 10.4 4.6 2.2 12.7 4.2 8.1 6.6 5.4 22.6 8.5 9.8 5.9 5.4 6.7 8.2 10.3 14.9 6.3 2.9 3.2 11.9 4.2 11.9 6.7 5.9 4.1 3.5 8.5 7.1 3.8 4.2 19.7 10.8 4.5 4.7 25.1 7.8 12.0 4.4 3.3 9.1 7.7 7.9 5.2 6.9 3.4 1.0 9.5 7.1 1.4 5.4 4.6 8.1 4.3 6.1 13.1 0.2 22.8 7.3 12.2 9.6 0.9 5.6 8.9 2.7 30.4 1.5 5.7 5.9 18.6 7.6 2.1 6.3 5.7 2.0 3.2 3.1 4.3 5.0 2.9 13.7 3.4 12.8 3.3 3.9 14.9 1.1 7.0 2.9 3.5 2.9 7.9 9.5 0.9 4.4 0.4 3.3 7.0 6.0 1.2 4.3 2.0 1.9 11.6 10.8 16.4 5.9 9.1 2.1 3.7 12.2 4.3 3.1 15.5 1.9 0.9 3.4 5.8 0.5 2.9 2.6 4.6 5.8 2.3 5.2 1.1 2.6 0.3 9.5 1.0 6.9 7.1 1.4 12.2 12.5 11.0 14.4 8.5 9.8 10.3 14.9 11.9 7.8 KATNAL2 "DKFZP667C165, MGC33211" ENSG00000167216 "Katanin catalytic subunit A1 like 2" Q8IYT4 18 46917492-47102243 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 30.3;testis: 33.2" "Cell line enhanced" "Detected in many" "AN3-CA: 14.8;Daudi: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040712, HPA042029" Approved Approved "Nucleoplasm,Intermediate filaments" "Nucleoplasm, Intermediate filaments" "HPA040712: , HPA042029: " "unprognostic (3.40e-1)" "unprognostic (7.75e-2)" "unprognostic (9.00e-3)" "unprognostic (9.28e-2)" "unprognostic (1.74e-2)" "unprognostic (6.55e-3)" "unprognostic (6.97e-2)" "unprognostic (1.28e-2)" "unprognostic (3.90e-2)" "unprognostic (5.36e-2)" "unprognostic (9.52e-6)" "unprognostic (1.28e-1)" "prognostic favourable (1.24e-7)" "unprognostic (1.64e-1)" "unprognostic (7.14e-4)" "unprognostic (1.06e-3)" "unprognostic (1.61e-1)" 5.5 2.9 8.2 4.1 9.7 2.8 7.1 4.0 7.5 2.5 2.4 11.3 2.5 1.8 2.8 7.1 2.7 8.6 5.1 4.3 8.1 7.6 9.5 5.2 4.6 3.4 9.6 6.2 3.1 3.3 30.3 7.0 2.2 9.0 3.4 3.1 6.4 3.4 3.7 6.0 8.0 1.5 2.3 8.7 3.3 2.0 33.2 6.3 2.4 15.5 1.1 3.0 2.3 2.5 3.1 0.6 2.7 1.3 0.8 1.5 0.3 1.9 4.3 2.3 14.8 4.8 5.9 1.1 1.8 1.6 1.5 1.9 0.2 5.0 19.6 1.5 2.8 0.6 4.7 0.5 1.1 2.0 2.5 0.8 1.3 0.3 2.0 1.2 1.9 12.1 1.8 2.5 0.6 0.5 0.7 1.5 8.4 1.9 1.1 2.6 5.3 2.6 5.4 1.1 0.0 4.7 0.4 5.4 5.9 1.9 0.4 0.6 11.2 10.9 1.0 5.0 0.5 1.9 1.2 1.3 1.0 13.2 2.7 12.4 9.5 1.7 0.7 0.5 1.1 1.3 0.9 2.2 0.9 0.5 0.3 3.1 1.5 1.4 2.7 0.8 0.9 0.6 0.2 0.3 8.2 9.7 4.0 7.5 8.1 7.6 9.6 6.2 9.0 6.3 KCMF1 "DEBT91, DKFZP434L1021, PCMF, ZZZ1" ENSG00000176407 "Potassium channel modulatory factor 1" Q9P0J7 2 84971093-85059472 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030383, HPA030384" Enhanced Enhanced Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA030383: AB_10599977, HPA030384: AB_10601230" "unprognostic (8.01e-2)" "unprognostic (1.98e-2)" "unprognostic (9.95e-2)" "unprognostic (7.42e-3)" "unprognostic (1.24e-2)" "unprognostic (8.54e-2)" "prognostic unfavourable (2.33e-7)" "unprognostic (5.68e-3)" "unprognostic (1.43e-1)" "unprognostic (9.81e-2)" "prognostic unfavourable (6.10e-5)" "unprognostic (4.98e-2)" "prognostic unfavourable (4.18e-6)" "unprognostic (6.11e-2)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (1.01e-1)" 19.2 13.3 17.9 20.2 16.0 23.6 26.1 13.4 18.6 15.0 20.2 10.7 20.3 15.4 16.3 18.8 28.5 12.8 17.9 30.4 16.5 12.0 14.8 20.7 16.4 18.8 13.7 11.1 17.2 48.6 14.7 18.7 20.5 14.4 17.5 21.4 14.0 19.4 15.7 67.2 17.6 20.6 25.7 10.3 16.7 16.8 29.0 11.5 19.7 18.7 21.8 22.5 23.9 34.0 4.0 4.2 8.1 3.4 2.8 8.8 1.5 27.1 21.4 19.1 14.7 20.2 19.5 32.5 29.1 27.1 28.0 18.7 26.1 29.4 29.6 29.3 39.4 18.1 14.8 28.2 36.9 22.1 10.4 18.9 16.1 26.6 39.5 20.7 18.1 20.1 44.6 27.4 76.0 21.0 18.7 23.6 27.9 25.1 20.0 11.5 20.8 18.0 14.4 26.8 18.5 25.3 23.9 18.4 13.8 16.9 21.6 28.2 10.0 13.2 17.9 28.6 27.9 26.6 30.2 26.9 33.2 30.0 21.5 15.3 21.4 5.0 2.6 8.1 4.5 2.2 3.6 3.5 3.2 3.4 2.2 4.0 2.8 3.1 7.5 2.8 3.4 4.2 8.8 1.5 17.9 16.0 13.4 18.6 16.5 12.0 13.7 11.1 14.4 11.5 KDM2A "CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA" ENSG00000173120 "Lysine demethylase 2A" Q9Y2K7 11 67119269-67258087 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012272, HPA044251" Supported Approved Nucleoplasm Nucleoplasm "CAB012272: , HPA044251: " "unprognostic (7.43e-2)" "unprognostic (1.84e-1)" "unprognostic (4.09e-1)" "unprognostic (8.66e-2)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (6.05e-2)" "unprognostic (2.84e-1)" "unprognostic (4.46e-1)" "unprognostic (2.04e-3)" "unprognostic (3.27e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-2)" "unprognostic (3.30e-1)" "unprognostic (1.05e-1)" "unprognostic (5.61e-2)" "unprognostic (9.45e-3)" 19.6 14.6 18.6 25.3 23.9 38.1 21.0 36.5 22.8 20.0 21.9 17.8 20.7 15.3 32.0 18.6 32.7 20.2 19.3 18.8 17.4 12.7 16.8 20.3 24.3 30.1 17.9 14.9 27.4 15.3 26.1 21.1 26.0 17.5 23.3 17.1 21.0 22.2 20.5 32.8 28.7 24.1 25.0 14.6 29.0 19.8 27.6 18.6 32.2 19.9 20.3 37.3 24.9 25.9 7.2 1.9 5.0 1.9 4.6 5.2 2.8 25.0 15.1 9.2 14.3 9.2 13.3 6.9 11.0 12.8 19.7 13.6 23.6 13.2 19.3 19.3 15.5 24.5 15.2 10.9 16.0 32.4 6.8 14.2 18.0 5.9 9.7 12.1 19.7 11.0 13.3 19.3 13.5 14.3 13.1 27.3 9.5 16.7 15.6 8.8 18.6 13.0 19.9 15.5 10.8 8.3 15.8 12.5 10.0 35.2 20.3 20.9 30.5 12.3 19.2 13.3 8.9 18.2 9.4 15.2 16.7 12.3 11.6 8.7 9.1 0.6 1.9 0.5 4.8 1.5 5.2 6.4 3.6 4.2 1.2 7.2 3.8 3.5 5.0 4.6 1.0 1.9 4.3 2.8 18.6 23.9 36.5 22.8 17.4 12.7 17.9 14.9 17.5 18.6 KDM2B "CXXC2, Fbl10, FBXL10, JHDM1B, PCCX2" ENSG00000089094 "Lysine demethylase 2B" Q8NHM5 12 121429097-121581015 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071257 Uncertain Nucleoplasm Nucleoplasm "HPA071257: " "unprognostic (7.67e-2)" "unprognostic (3.72e-3)" "unprognostic (2.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.37e-1)" "prognostic favourable (6.74e-6)" "unprognostic (1.16e-1)" "unprognostic (5.45e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-1)" "prognostic favourable (8.64e-4)" "unprognostic (1.77e-1)" "unprognostic (4.44e-3)" "unprognostic (1.44e-2)" "unprognostic (3.90e-2)" "unprognostic (7.07e-2)" "unprognostic (4.82e-2)" 6.2 6.3 13.9 20.1 15.7 14.9 7.0 31.1 25.1 9.2 7.6 12.3 5.2 8.2 9.9 7.3 14.4 10.8 7.9 5.8 11.8 7.2 6.6 10.2 9.5 21.3 14.3 15.1 14.1 8.2 13.0 8.2 7.2 12.2 6.6 7.7 8.1 9.1 6.8 11.7 18.9 13.1 8.1 13.2 16.3 7.4 9.8 14.5 27.0 8.2 5.5 20.9 11.1 11.6 11.5 5.0 4.2 3.6 2.6 8.3 4.0 6.6 8.5 16.7 5.1 4.7 4.8 17.1 6.6 9.0 9.6 8.1 11.5 3.8 32.6 9.7 6.0 5.8 17.8 6.5 7.3 13.5 11.5 18.8 7.7 10.3 5.1 22.0 14.5 3.8 3.9 8.7 6.6 6.9 14.2 4.6 5.0 9.9 23.9 26.4 26.9 6.9 27.4 8.5 16.1 5.3 12.9 18.3 10.8 11.3 6.7 6.7 12.6 24.2 8.7 10.0 7.5 9.5 6.4 10.9 9.6 31.8 9.2 17.3 6.2 4.2 3.6 2.8 8.3 3.2 6.3 11.5 6.6 4.8 5.0 10.6 5.9 7.5 0.5 2.6 1.9 4.8 5.5 4.0 13.9 15.7 31.1 25.1 11.8 7.2 14.3 15.1 12.2 14.5 KDM8 "FLJ13798, JMJD5" ENSG00000155666 "Lysine demethylase 8" Q8N371 16 27203495-27221768 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Transcription, Transcription regulation" "Aminopeptidase, Chromatin regulator, Dioxygenase, Hydrolase, Oxidoreductase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026545 Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA026545: AB_1852015" "unprognostic (1.39e-1)" "unprognostic (1.37e-3)" "unprognostic (2.80e-1)" "unprognostic (2.16e-2)" "unprognostic (3.21e-1)" "unprognostic (1.22e-2)" "unprognostic (2.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.95e-2)" "unprognostic (3.41e-1)" "prognostic favourable (1.75e-4)" "unprognostic (1.22e-1)" "unprognostic (2.75e-2)" "unprognostic (5.33e-2)" "unprognostic (2.71e-1)" "unprognostic (2.04e-1)" "unprognostic (3.92e-3)" 1.9 3.2 2.7 3.6 3.5 1.4 2.1 5.9 5.9 2.2 4.2 3.7 3.2 12.0 3.1 2.2 2.1 2.5 2.5 2.0 2.7 3.2 2.3 44.9 2.0 3.3 2.3 5.1 3.0 4.5 2.8 3.3 1.7 3.7 2.9 1.9 2.1 2.6 2.5 4.0 1.9 16.8 1.9 2.2 3.7 2.3 2.2 2.2 5.9 2.9 2.0 3.7 2.8 2.2 5.6 6.5 1.3 3.4 2.2 8.2 3.5 1.6 3.7 6.3 3.2 1.6 1.8 3.4 2.1 2.3 4.7 4.2 3.1 2.9 9.5 3.6 3.5 1.9 3.6 3.2 2.8 10.9 5.4 6.0 4.1 7.2 3.4 4.2 7.2 2.5 2.5 3.1 2.0 3.6 7.6 5.8 2.9 2.8 4.2 7.6 11.0 2.2 6.2 3.9 8.4 1.8 1.9 5.9 3.8 0.9 3.0 2.2 3.2 5.6 4.1 5.7 2.9 2.0 2.2 3.6 3.8 7.6 2.3 3.9 0.5 0.4 3.2 1.3 4.2 3.4 3.6 3.2 6.2 6.0 3.0 5.6 6.0 8.2 0.1 2.2 2.9 6.5 3.6 3.5 2.7 3.5 5.9 5.9 2.7 3.2 2.3 5.1 3.7 2.2 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078259-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 31.8;TIME: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB004028 Enhanced Supported "Plasma membrane" "Intracellular and membrane" 7400000 "Plasma membrane" "CAB004028: AB_2212507" "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavourable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 19.7 6.2 1.8 4.4 3.1 0.4 20.5 1.1 2.2 11.4 6.0 1.8 11.5 2.3 28.8 10.2 5.2 9.5 6.2 12.1 2.3 1.7 7.8 10.4 13.2 14.1 3.1 2.9 6.0 8.1 8.0 6.8 34.5 3.9 9.5 1.4 27.6 7.1 10.3 5.3 3.0 3.8 7.7 2.6 4.4 4.2 5.3 1.2 0.5 20.0 5.3 3.0 4.4 12.0 0.1 0.1 0.7 0.0 0.2 0.2 0.1 0.0 0.0 1.7 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.7 0.0 0.0 0.3 0.0 0.0 0.2 31.8 0.0 0.0 0.2 0.0 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 1.8 3.1 1.1 2.2 2.3 1.7 3.1 2.9 3.9 1.2 KDSR "DHSR, FVT1, SDR35C1" ENSG00000119537 "3-ketodihydrosphingosine reductase" Q06136 18 63327726-63367510 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Cancer-related genes, Disease mutation, Palmoplantar keratoderma, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 37.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003673, HPA044884" Approved "CAB003673: AB_425440, HPA044884: " "unprognostic (4.44e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-2)" "unprognostic (4.56e-2)" "unprognostic (5.88e-3)" "unprognostic (7.50e-3)" "unprognostic (1.80e-2)" "unprognostic (2.66e-1)" "unprognostic (2.97e-1)" "unprognostic (1.97e-1)" "unprognostic (2.70e-2)" "unprognostic (6.81e-2)" "prognostic favourable (9.53e-6)" "unprognostic (3.32e-2)" "unprognostic (5.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-3)" 21.1 19.4 19.0 11.1 22.4 6.4 29.7 12.5 17.2 18.2 17.3 23.9 14.2 10.0 19.4 30.0 17.8 14.3 17.7 15.8 19.7 16.9 21.3 52.6 15.3 11.5 32.1 14.6 29.1 14.3 19.6 10.5 24.9 19.5 18.0 11.0 15.9 16.1 17.4 12.4 28.8 13.1 18.9 39.0 9.1 11.8 10.4 23.3 8.8 21.2 12.3 9.9 19.9 22.8 4.0 5.6 0.9 5.6 9.8 19.5 3.7 5.9 2.6 2.8 3.1 22.0 16.5 5.4 19.5 12.0 4.3 5.8 1.1 4.0 6.0 8.4 7.6 26.1 3.5 11.0 5.3 11.2 5.8 4.6 3.5 1.3 16.9 8.4 3.2 15.7 20.9 6.9 19.8 4.2 3.7 8.6 11.4 2.4 9.3 3.9 3.3 9.8 6.3 8.1 8.5 11.9 3.8 3.5 6.8 9.4 4.6 8.4 2.5 4.8 10.0 18.4 4.4 6.1 8.5 37.6 17.1 3.4 13.8 5.2 5.4 0.0 3.7 0.3 4.8 5.6 19.5 4.0 10.2 7.6 5.6 3.6 7.3 4.6 0.9 9.8 2.6 2.8 12.9 3.7 19.0 22.4 12.5 15.9 19.7 16.9 32.1 14.6 19.5 23.3 KEL "CD238, ECE3" ENSG00000197993 "Kell blood group, metallo-endopeptidase" P23276 7 142941114-142962681 "Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 21.1;testis: 36.4" "Group enriched" "Detected in some" 12 "HEL: 14.9;K-562: 12.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 7 "intermediate monocyte: 1.4" "Lineage enriched" "Detected in single" 14 "monocytes: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA064442 Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA064442: " "unprognostic (5.78e-3)" "unprognostic (1.08e-5)" "unprognostic (5.29e-3)" "unprognostic (4.85e-3)" "unprognostic (9.68e-2)" "unprognostic (1.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (5.18e-2)" "unprognostic (1.08e-2)" "unprognostic (3.71e-2)" "unprognostic (3.57e-2)" "unprognostic (2.29e-3)" "unprognostic (9.24e-2)" "unprognostic (7.05e-2)" "unprognostic (3.32e-2)" "unprognostic (3.25e-3)" 0.2 0.0 0.9 2.5 1.1 21.1 0.2 0.2 0.4 0.4 0.2 0.3 0.2 0.0 0.2 0.2 0.6 0.1 0.2 0.2 1.4 0.7 0.4 0.2 1.4 5.0 2.0 0.2 0.2 0.2 0.0 0.2 1.1 0.3 0.2 0.0 0.3 2.5 0.2 0.2 0.0 0.5 0.2 4.4 3.8 0.0 36.4 0.3 0.4 0.2 0.2 3.7 0.2 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.1 0.1 0.0 0.0 0.5 0.2 0.3 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 1.1 0.2 0.4 1.4 0.7 2.0 0.2 0.3 0.3 KHK ENSG00000138030 Ketohexokinase P50053 2 27086747-27100772 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 60.2;kidney: 38.4;liver: 67.0" "Cell line enhanced" "Detected in many" "HEL: 18.5;Hep G2: 26.9" "Group enriched" "Detected in all" 7 "liver cancer: 62.2;renal cancer: 32.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007040 Enhanced Approved Cytosol 320000 Cytosol "HPA007040: AB_1079185" "unprognostic (8.44e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "prognostic unfavourable (7.62e-8)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (3.13e-2)" "unprognostic (1.67e-2)" "unprognostic (2.50e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.68e-2)" "unprognostic (2.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" 0.9 1.9 2.1 1.2 2.7 0.7 1.9 5.2 3.9 1.1 22.3 1.9 0.2 40.0 1.5 0.9 1.1 1.6 0.6 0.6 2.2 2.2 38.4 67.0 0.7 0.8 3.5 1.9 1.8 4.2 0.6 0.7 0.4 3.0 0.9 0.6 0.6 1.7 0.7 1.4 1.0 60.2 0.9 1.8 0.8 1.0 1.6 3.6 0.0 0.5 1.2 0.6 0.7 0.9 5.1 7.3 0.6 6.6 5.4 8.8 6.0 13.9 10.6 1.6 6.4 1.2 0.3 1.4 0.9 0.6 1.3 0.8 5.1 3.0 2.1 3.4 0.0 6.2 5.5 1.8 0.4 4.9 10.0 18.5 2.8 26.9 0.6 2.5 2.2 0.1 0.8 1.6 0.1 1.2 3.3 3.5 0.1 9.1 3.0 2.0 2.3 4.2 10.6 0.8 11.8 1.6 1.7 6.0 9.3 2.0 3.6 3.9 1.6 1.1 1.1 0.4 2.1 0.9 3.7 4.4 7.8 3.6 1.8 6.0 1.0 0.0 6.6 0.4 5.4 3.8 7.4 5.1 8.8 7.8 6.1 5.1 6.4 7.8 0.6 5.4 1.6 7.3 5.5 6.0 2.1 2.7 5.2 3.9 2.2 2.2 3.5 1.9 3.0 3.6 KIAA0391 "MRPP3, PRORP" ENSG00000100890 KIAA0391 O15091 14 35121846-35277614 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA020459 Approved Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA020459: " "unprognostic (6.44e-3)" "unprognostic (8.10e-2)" "unprognostic (7.71e-3)" "unprognostic (4.90e-2)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" "unprognostic (8.67e-2)" "unprognostic (1.94e-2)" "unprognostic (3.25e-4)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (9.67e-5)" "unprognostic (2.56e-1)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (6.65e-2)" 13.9 26.1 18.8 17.6 20.1 12.5 17.5 23.1 21.9 17.4 22.4 20.6 15.6 16.6 13.0 19.4 26.1 14.7 13.2 16.7 17.6 16.3 31.1 29.5 20.9 29.5 20.2 17.7 10.8 16.5 29.8 27.4 13.4 19.2 14.1 24.9 15.8 18.0 21.8 22.2 23.0 16.5 15.0 23.0 18.7 15.8 17.1 20.9 31.2 18.9 21.3 24.8 18.2 16.0 10.0 9.7 10.9 5.4 12.1 25.5 12.4 22.7 18.1 12.6 16.7 13.9 16.4 11.1 15.3 13.8 19.6 17.0 17.2 14.1 25.0 19.9 14.5 17.6 23.2 26.5 22.1 19.6 7.2 11.2 14.0 36.7 14.3 13.8 12.3 17.5 20.4 18.5 17.1 28.4 18.1 7.3 23.9 25.7 20.9 15.2 13.5 18.0 20.0 21.0 14.5 27.5 23.3 11.8 13.3 19.8 22.0 12.7 32.0 11.4 21.5 15.1 13.6 11.7 13.1 7.9 18.5 26.2 7.7 15.0 15.8 10.9 5.4 3.4 15.4 5.2 22.4 10.0 23.8 16.6 7.2 7.0 21.2 15.6 6.3 12.1 4.3 9.7 25.5 12.4 18.8 20.1 23.1 21.9 17.6 16.3 20.2 17.7 19.2 20.9 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 65.5" "Group enriched" "Detected in some" 13 "HEL: 47.7;HMC-1: 100.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 12.7;eosinophil: 10.0;NK-cell: 9.7" "Group enriched" "Detected in many" 6 "granulocytes: 12.7;NK-cells: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" 48000000 "Plasma membrane" "CAB003288: AB_2335702, CAB068253: , CAB072867: , HPA004471: AB_1078431, HPA073252: " "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favourable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 8.1 1.6 9.5 6.6 11.8 3.7 65.5 18.3 12.0 12.1 10.3 6.5 10.2 5.8 8.9 4.2 9.9 2.5 15.5 2.4 36.0 4.4 9.4 1.1 13.8 3.8 3.6 6.0 28.5 2.1 1.3 2.3 6.2 5.7 9.6 10.4 20.7 12.9 6.9 1.3 14.6 8.9 10.2 3.9 3.2 12.8 4.0 4.5 0.4 28.9 4.3 4.9 9.8 12.5 0.0 1.8 12.7 0.9 9.7 1.9 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.6 0.9 2.5 3.2 0.0 0.0 0.0 0.0 1.4 0.0 0.5 0.0 2.1 0.0 1.1 47.7 0.0 0.0 0.0 0.0 100.2 0.0 0.0 0.0 0.0 5.6 0.6 0.1 0.0 0.0 0.2 0.4 1.3 0.0 0.1 0.0 0.0 0.0 4.7 1.2 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 12.7 0.0 10.0 0.1 0.0 1.9 0.0 0.3 0.7 1.8 0.0 0.0 0.0 0.8 9.7 0.9 0.0 0.0 0.1 9.5 11.8 18.3 12.0 36.0 4.4 3.6 6.0 5.7 4.5 KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.4;lymphoid tissue: 88.5;salivary gland: 96.5" "Group enriched" "Detected in some" 4 "EFO-21: 9.4;HaCaT: 29.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 11 "pons and medulla: 10.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026340 Approved "Secreted in other tissues" 320000 "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favourable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavourable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" 5.5 0.0 0.2 1.1 0.2 0.0 4.9 0.2 0.6 24.5 1.7 2.0 0.4 0.0 5.1 2.7 103.4 9.7 61.8 0.4 0.9 0.0 0.2 0.6 12.3 0.2 0.2 0.2 2.3 25.0 0.0 2.1 0.4 10.7 18.8 0.0 5.1 96.5 1.6 0.3 49.8 0.6 0.3 0.2 0.2 18.7 7.7 0.2 0.9 0.2 65.2 88.5 0.7 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 9.4 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.9 0.0 0.2 0.2 10.7 0.2 KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix, uterine: 27.6;esophagus: 53.9;lymphoid tissue: 24.7;tongue: 33.3;vagina: 24.8" "Cell line enhanced" "Detected in some" "CACO-2: 1.2;HaCaT: 2.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025473 Uncertain "Secreted in other tissues" "CAB025473: " "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-3)" "unprognostic (1.15e-1)" "unprognostic (5.80e-3)" "unprognostic (4.99e-3)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "prognostic favourable (8.01e-4)" "unprognostic (8.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 27.6 2.0 0.0 0.0 3.6 1.2 0.2 53.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.7 0.0 16.6 0.0 0.0 0.4 4.3 0.1 0.2 0.0 0.4 0.5 0.0 0.2 0.0 33.3 24.7 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLK13 KLK-L4 ENSG00000167759 "Kallikrein related peptidase 13" Q9UKR3 19 51056206-51065114 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 100.5" "Cell line enriched" "Detected in some" 11 "HaCaT: 20.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 42.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062136 Enhanced "Secreted in other tissues" "HPA062136: " "unprognostic (1.99e-3)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (3.43e-1)" "unprognostic (2.99e-2)" "unprognostic (1.69e-1)" "unprognostic (6.76e-2)" "unprognostic (2.18e-2)" "unprognostic (8.30e-2)" "unprognostic (7.07e-6)" "unprognostic (7.33e-2)" "unprognostic (2.53e-1)" "unprognostic (6.38e-2)" "unprognostic (7.06e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.2 15.7 0.4 0.2 0.1 0.2 0.3 0.1 100.5 0.2 0.9 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.4 1.7 0.0 0.5 0.1 0.2 0.1 0.0 0.3 12.4 0.1 1.2 2.1 0.4 0.1 0.1 0.1 0.2 6.1 0.1 0.1 0.1 17.9 12.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 20.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.1 KLK14 KLK-L6 ENSG00000129437 "Kallikrein related peptidase 14" Q9P0G3 19 51077495-51084245 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 14.2" "Cell line enhanced" "Detected in some" "HaCaT: 13.7;HEK 293: 3.9;U-266/84: 7.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026228 Uncertain "Secreted in other tissues" "CAB026228: " "unprognostic (2.08e-1)" "unprognostic (1.22e-1)" "unprognostic (2.44e-2)" "unprognostic (2.60e-2)" "unprognostic (1.23e-1)" "unprognostic (6.12e-2)" "unprognostic (4.91e-2)" "unprognostic (5.79e-2)" "unprognostic (7.84e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (8.87e-2)" "unprognostic (2.04e-8)" "unprognostic (1.93e-1)" "unprognostic (3.74e-3)" "unprognostic (1.94e-2)" "unprognostic (8.08e-2)" 0.2 0.0 0.4 0.2 1.2 0.1 2.7 2.1 0.9 3.8 0.6 1.8 0.4 0.9 1.2 0.8 0.3 1.1 0.6 0.5 0.1 0.1 0.5 0.4 0.3 0.9 0.4 0.0 0.3 0.0 0.7 0.4 1.1 0.7 0.3 14.2 1.0 0.0 0.3 0.4 0.8 0.7 0.1 0.6 0.2 3.9 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.7 0.7 0.1 0.9 0.6 0.6 0.7 0.2 0.0 0.0 0.2 1.7 2.1 0.8 0.6 0.3 13.7 0.2 0.3 0.0 0.5 3.9 0.3 1.0 0.0 0.2 0.3 0.3 0.4 0.4 0.5 0.6 0.2 0.3 0.5 0.0 1.2 0.2 0.8 0.8 1.5 0.2 0.1 0.8 0.0 0.7 0.1 0.0 0.3 1.2 0.4 0.6 0.0 0.0 0.2 0.6 0.9 0.2 3.6 7.1 0.5 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 KLK15 "ACO, HSRNASPH, prostinogen" ENSG00000174562 "Kallikrein related peptidase 15" Q9H2R5 19 50825289-50837213 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.7;salivary gland: 9.7" "Cell line enriched" "Detected in some" 5 "RPMI-8226: 7.2" "Cancer enhanced" "Detected in some" "prostate cancer: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA019802 Uncertain "Secreted to blood" "HPA019802: AB_1852601" "unprognostic (6.06e-2)" "unprognostic (2.85e-1)" "unprognostic (8.13e-2)" "unprognostic (2.90e-1)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-1)" "unprognostic (2.72e-2)" 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 2.1 9.7 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 2.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "prostate: 163.5" "Cell line enhanced" "Detected in many" "NB-4: 9.9" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA000764 Supported "Secreted in male reproductive system" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.0 0.1 0.0 0.1 0.0 1.1 0.2 0.0 0.6 0.0 0.0 0.0 0.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.5 0.0 0.1 2.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.2 0.0 2.2 1.9 5.7 2.2 1.6 1.3 0.5 1.7 1.1 0.6 1.6 0.0 0.8 4.9 0.5 0.3 0.2 0.2 0.6 0.7 1.8 0.2 0.0 2.0 0.2 0.0 0.3 1.7 1.1 0.0 1.3 0.4 0.0 0.3 3.1 0.4 0.3 0.3 0.4 0.0 1.4 1.9 0.3 1.8 1.2 9.9 1.1 0.0 0.9 0.0 2.8 0.0 1.6 0.9 1.5 0.3 1.3 1.3 1.2 0.4 0.8 1.3 1.9 4.8 1.6 1.8 3.2 0.8 1.9 1.7 1.4 0.9 2.2 1.6 1.2 1.0 1.0 1.0 0.8 1.0 0.5 2.2 0.8 1.3 5.7 1.6 0.8 1.9 0.4 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 KLK3 "APS, PSA" ENSG00000142515 "Kallikrein related peptidase 3" P07288 19 50854915-50860764 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 115 "prostate: 447.4" "Group enriched" "Detected in some" 135 "BEWO: 21.9;NB-4: 18.5;RPMI-8226: 12.2;SH-SY5Y: 7.3;U-2197: 7.5" "Cancer enriched" "Detected in some" 3905 "prostate cancer: 4241.6" "Region enriched" "Detected in single" 8 "cerebral cortex: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000070, HPA000764" Enhanced "Secreted in male reproductive system" "CAB000070: , HPA000764: AB_1079700" "unprognostic (5.06e-3)" "unprognostic (5.60e-2)" "unprognostic (9.93e-2)" "unprognostic (3.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.13e-3)" "unprognostic (1.94e-1)" "unprognostic (4.64e-1)" "unprognostic (3.15e-1)" 0.1 0.3 0.0 0.1 0.0 0.0 0.7 0.0 1.0 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 447.4 0.0 0.1 3.8 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.5 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 KLK4 "EMSP, EMSP1, KLK-L1, PRSS17, PSTS" ENSG00000167749 "Kallikrein related peptidase 4" Q9Y5K2 19 50906352-50910738 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Hydrolase, Protease, Serine protease" "Amelogenesis imperfecta, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "prostate: 79.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 8.2;HaCaT: 10.1;SK-BR-3: 6.5" "Cancer enriched" "Detected in many" 55 "prostate cancer: 463.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051839 Enhanced "Secreted in male reproductive system" "HPA051839: " "unprognostic (3.58e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-3)" "unprognostic (1.66e-3)" "unprognostic (3.11e-2)" "unprognostic (4.35e-1)" "unprognostic (3.18e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-2)" "unprognostic (8.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.20e-3)" "unprognostic (3.27e-3)" "unprognostic (2.21e-2)" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" 0.2 0.8 0.1 0.3 0.1 0.1 0.7 0.2 0.5 2.0 1.2 0.0 3.8 1.8 1.5 7.7 0.4 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.5 79.3 0.8 0.2 3.2 2.1 0.7 2.4 1.2 0.6 0.1 0.1 0.3 0.6 0.1 0.0 8.7 0.0 0.0 0.2 0.2 0.1 0.4 0.6 0.1 0.0 0.3 0.0 5.0 2.1 0.2 0.3 0.0 0.0 4.5 0.1 0.0 0.0 0.0 4.6 8.2 0.5 0.4 0.1 10.1 0.0 5.4 0.0 1.3 1.4 1.6 3.7 1.7 0.0 1.7 2.3 0.0 2.6 0.0 0.0 0.0 0.9 4.2 0.0 1.2 0.1 2.5 0.1 0.4 0.3 0.5 1.1 0.0 3.3 0.0 0.6 0.3 6.5 0.0 5.2 0.4 1.1 0.3 0.3 1.3 0.3 2.6 1.0 0.5 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.5 0.3 0.2 0.2 0.0 0.5 0.1 KLK5 "KLK-L2, SCTE" ENSG00000167754 "Kallikrein related peptidase 5" Q9Y337 19 50943303-50953093 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skin 1: 69.2;tongue: 67.3" "Group enriched" "Detected in some" 40 "A-431: 85.3;HaCaT: 83.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 112.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014343, CAB025503, CAB026341" Enhanced "Secreted in other tissues" "CAB025503: , CAB026341: , HPA014343: AB_1852603" "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "prognostic unfavourable (2.33e-4)" "unprognostic (4.30e-4)" "unprognostic (3.01e-1)" "prognostic unfavourable (9.79e-4)" "unprognostic (3.04e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" "unprognostic (2.21e-1)" "unprognostic (2.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.16e-3)" "prognostic unfavourable (3.85e-6)" 1.1 0.0 0.7 0.4 0.2 0.0 12.1 0.2 0.5 3.8 0.3 0.2 0.2 0.1 1.4 0.9 6.5 0.2 0.3 0.2 0.2 0.1 0.6 0.2 2.5 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.4 0.2 0.0 0.3 7.0 0.2 0.4 69.2 0.2 0.2 0.2 0.2 0.0 3.3 0.2 0.4 0.3 67.3 4.4 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 83.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.2 0.5 0.2 0.1 0.2 0.2 0.4 0.2 KLK6 "Bssp, Klk7, neurosin, PRSS18, PRSS9" ENSG00000167755 "Kallikrein related peptidase 6" Q92876 19 50958631-50969673 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.6;esophagus: 48.9" "Group enriched" "Detected in some" 14 "A-431: 68.4;CAPAN-2: 163.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 131.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons and medulla: 175.6" "Group enriched" "Detected in many" 8 "midbrain: 106.3;pons and medulla: 164.1;thalamus: 62.4" HPA051837 Supported "Nucleoplasm,Nuclear membrane,Cytokinetic bridge" "Secreted in other tissues" 6800000 Nucleoplasm "Nuclear membrane, Cytokinetic bridge" "HPA051837: " "unprognostic (7.30e-2)" "unprognostic (3.32e-1)" "unprognostic (6.58e-2)" "prognostic unfavourable (1.38e-5)" "unprognostic (1.10e-1)" "unprognostic (2.31e-1)" "prognostic unfavourable (8.85e-4)" "unprognostic (3.02e-1)" "unprognostic (2.46e-1)" "prognostic unfavourable (7.82e-4)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (9.07e-2)" "prognostic unfavourable (1.27e-4)" 0.9 0.9 9.7 0.9 23.5 0.9 6.5 3.3 42.2 10.0 1.0 82.0 0.0 1.1 2.0 1.2 48.9 24.6 3.8 0.9 20.1 11.8 9.0 0.9 0.9 0.9 46.1 14.9 0.9 0.9 0.9 0.2 0.9 44.3 1.0 0.9 0.0 5.9 2.8 0.9 2.9 0.9 1.0 97.6 5.1 1.0 1.5 32.6 0.0 0.9 15.7 28.1 0.9 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.1 163.7 0.0 1.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.1 5.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 23.5 3.3 23.1 20.1 11.8 46.1 14.9 44.3 32.6 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976482-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 29.1;skin 1: 77.5;tongue: 90.2" "Group enriched" "Detected in some" 6 "CAPAN-2: 6.6;HaCaT: 25.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" 960000 "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavourable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 2.1 0.3 5.4 0.3 4.3 0.4 5.6 0.5 11.3 5.4 0.3 0.0 0.0 0.5 0.7 0.3 29.1 7.8 3.3 0.2 4.8 0.5 2.6 0.2 1.6 0.3 0.3 3.5 1.0 0.2 0.2 0.1 0.5 4.2 0.3 0.2 0.0 7.4 0.3 0.6 77.5 0.3 0.4 0.3 0.5 0.4 0.3 0.0 0.0 0.4 90.2 15.3 0.2 9.0 1.1 0.4 1.3 0.8 2.1 1.0 0.6 2.6 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.5 6.6 0.0 1.0 0.0 25.9 0.0 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 1.3 0.8 0.4 0.4 0.4 0.7 0.6 0.6 0.4 0.4 1.1 1.0 0.9 0.9 2.1 0.4 0.4 0.7 0.6 5.4 4.3 0.5 11.3 4.8 0.5 0.3 3.5 4.2 0.0 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 43.6;skin 1: 40.4;tongue: 46.9" "Group enriched" "Detected in some" 7 "A-431: 31.5;CAPAN-2: 41.3;HaCaT: 30.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "hippocampal formation: 39.6" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" 950000 Vesicles "CAB019393: , HPA035761: " "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavourable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavourable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavourable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavourable (6.17e-4)" 1.6 0.0 0.1 0.4 0.1 0.0 4.5 1.0 0.3 8.1 0.7 0.1 0.1 0.0 1.1 0.7 43.6 6.7 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 1.1 0.1 0.0 0.1 0.4 0.6 0.3 0.0 0.3 6.0 0.1 0.3 40.4 0.1 0.1 0.6 0.3 0.0 0.7 0.1 0.5 0.3 46.9 11.1 0.3 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 0.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.6 41.3 0.0 0.8 0.0 30.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.3 0.1 0.0 0.1 0.1 0.6 0.1 KLK9 KLK-L3 ENSG00000213022 "Kallikrein related peptidase 9" Q9UKQ9 19 51003111-51009634 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "tongue: 37.6" "Group enriched" "Detected in some" 27 "HaCaT: 1.2;HBEC3-KT: 4.1" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025049 Enhanced "Secreted to digestive system" "CAB025049: " "unprognostic (3.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 37.6 3.8 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KMO ENSG00000117009 "Kynurenine 3-monooxygenase" O15229 1 241532134-241595642 "Enzymes, Predicted membrane proteins" "Pyridine nucleotide biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 20.3;liver: 58.6;placenta: 26.0" "Cell line enhanced" "Detected in some" "Daudi: 5.2;RPMI-8226: 7.6;RPTEC TERT1: 19.6;SK-BR-3: 10.1;U-698: 8.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 79 "classical monocyte: 5.2;intermediate monocyte: 14.7;memory B-cell: 16.1;myeloid DC: 5.3;naive B-cell: 20.3;non-classical monocyte: 14.7;plasmacytoid DC: 11.1" "Group enriched" "Detected in many" 97 "B-cells: 20.3;dendritic cells: 11.1;monocytes: 14.7" "Region enriched" "Detected in single" 4 "thalamus: 1.3" "Low region specificity" "Detected in single" "HPA031115, HPA056942" Enhanced "HPA031115: AB_10601924, HPA056942: " "unprognostic (4.27e-2)" "unprognostic (3.35e-2)" "unprognostic (3.95e-2)" "unprognostic (7.48e-3)" "unprognostic (8.37e-3)" "unprognostic (2.63e-1)" "unprognostic (9.79e-2)" "unprognostic (3.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.75e-3)" "unprognostic (8.07e-2)" "unprognostic (1.47e-1)" "prognostic unfavourable (6.49e-8)" "unprognostic (1.60e-2)" "unprognostic (3.65e-2)" "unprognostic (3.36e-2)" "unprognostic (6.81e-2)" 3.7 0.6 0.5 3.3 0.6 0.3 2.4 0.2 0.9 0.3 0.4 0.2 0.0 0.0 2.7 0.1 0.3 0.4 0.5 0.4 0.8 0.4 14.2 58.6 6.5 3.2 0.3 0.3 0.4 0.3 0.0 0.4 26.0 0.3 0.4 0.3 0.3 0.5 0.0 0.2 0.3 1.0 0.1 0.5 8.0 0.4 0.6 0.1 0.7 0.4 0.1 4.5 1.4 0.3 20.3 11.1 0.1 14.7 0.0 0.0 2.8 0.1 1.6 0.1 0.0 0.0 0.2 0.2 0.1 0.1 0.2 0.4 0.0 0.2 5.2 0.4 0.0 2.1 0.0 0.2 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.2 0.7 0.1 0.1 0.0 0.1 0.8 0.0 0.2 0.0 2.2 0.9 0.4 1.4 0.1 7.6 19.6 4.0 0.2 0.1 0.0 10.1 0.0 3.9 1.6 0.0 0.0 0.1 0.0 1.3 0.3 0.5 8.1 0.2 1.9 1.6 0.0 5.2 0.1 0.0 14.7 0.0 16.1 0.0 0.0 5.3 20.3 0.0 0.0 0.1 0.0 14.7 11.1 0.0 2.8 0.5 0.6 0.2 0.9 0.8 0.4 0.3 0.3 0.3 0.1 KMT2A "ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1" ENSG00000118058 "Lysine methyltransferase 2A" Q03164 11 118436490-118526832 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017794, CAB024270, HPA044910" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB017794: , CAB024270: , HPA044910: " "unprognostic (6.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.83e-1)" "unprognostic (4.56e-1)" "unprognostic (4.96e-2)" "unprognostic (1.72e-3)" "unprognostic (4.52e-3)" "unprognostic (6.07e-2)" "unprognostic (1.61e-1)" "unprognostic (8.46e-2)" "unprognostic (3.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.91e-3)" "unprognostic (7.90e-2)" "unprognostic (3.73e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" 14.4 11.3 17.7 17.0 19.2 28.6 16.8 43.8 21.2 17.3 14.6 19.8 18.1 8.5 21.8 17.1 10.6 15.7 14.1 10.2 17.3 13.4 13.1 9.3 15.3 19.6 16.6 18.7 35.6 16.8 28.9 21.8 10.2 15.4 15.6 12.4 14.4 14.2 19.2 11.1 16.8 14.2 15.2 12.1 15.7 12.3 7.9 23.4 16.6 16.6 7.8 19.4 18.8 24.6 6.7 3.5 8.3 2.0 6.5 5.3 0.8 11.9 5.5 14.9 11.2 9.1 10.9 4.4 5.4 7.8 5.7 6.6 11.1 8.7 14.7 11.1 7.9 10.4 15.8 5.9 11.3 16.2 6.1 28.8 5.1 6.0 5.1 17.2 5.6 5.2 6.1 12.4 16.7 8.8 18.7 12.6 7.1 9.3 11.4 10.1 9.0 8.2 8.7 14.3 4.9 8.4 9.0 12.3 8.0 13.5 4.4 2.8 7.6 5.8 13.0 9.8 8.8 7.1 9.6 3.7 2.8 9.9 3.7 12.7 5.8 8.3 2.0 4.6 5.3 1.3 4.3 6.2 4.8 4.6 0.8 6.7 4.9 4.8 1.3 6.5 1.4 3.5 3.9 0.8 17.7 19.2 43.8 21.2 17.3 13.4 16.6 18.7 15.4 23.4 KMT2B "CXXC10, HRX2, KIAA0304, MLL1B, MLL2, MLL4, TRX2, WBP7" ENSG00000272333 "Lysine methyltransferase 2B" Q9UMN6 19 35718019-35738878 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006487 Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006487: AB_1080587" "unprognostic (1.09e-2)" "unprognostic (3.53e-2)" "unprognostic (3.41e-2)" "unprognostic (7.95e-2)" "unprognostic (9.92e-2)" "unprognostic (3.53e-3)" "unprognostic (2.33e-2)" "unprognostic (4.57e-2)" "unprognostic (7.28e-2)" "unprognostic (2.07e-2)" "unprognostic (3.13e-3)" "unprognostic (2.63e-3)" "unprognostic (9.47e-3)" "unprognostic (2.10e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" 10.2 9.3 11.4 14.2 13.1 18.4 10.4 23.9 11.4 10.0 12.0 14.2 12.9 13.8 13.0 7.1 11.4 11.6 12.6 7.5 11.0 5.3 9.9 8.9 10.6 14.7 14.7 6.8 15.3 19.6 10.8 13.3 9.3 11.2 12.1 5.6 13.8 14.7 10.0 13.3 19.9 12.3 12.2 12.4 15.8 12.1 21.5 14.9 14.1 14.9 7.0 14.2 12.4 14.2 0.4 0.7 3.2 0.7 2.1 0.7 0.2 11.3 19.2 8.9 9.7 4.6 4.5 9.3 5.5 4.0 5.6 4.3 12.8 5.8 10.1 8.7 4.6 7.5 8.0 4.7 2.5 15.0 8.9 18.2 9.0 6.4 4.5 11.1 20.9 6.1 6.4 5.7 6.3 5.5 15.2 12.7 3.6 11.6 9.4 9.6 8.2 6.8 14.8 5.8 5.5 3.1 10.1 10.1 8.1 8.4 13.6 5.8 8.3 11.8 7.6 11.3 12.2 7.5 11.7 17.5 10.7 8.1 6.1 10.3 7.8 1.0 0.7 0.6 0.7 0.4 0.4 0.3 0.2 0.3 0.2 0.4 0.3 0.4 3.2 2.1 0.3 0.7 0.2 0.2 11.4 13.1 23.9 11.4 11.0 5.3 14.7 6.8 11.2 14.9 KMT2C "HALR, KIAA1506, MLL3" ENSG00000055609 "Lysine methyltransferase 2C" Q8NEZ4 7 152134922-152436005 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074736 Approved Nucleoplasm Nucleoplasm "HPA074736: " "unprognostic (7.75e-2)" "unprognostic (3.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.33e-2)" "unprognostic (1.31e-1)" "unprognostic (5.23e-3)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.06e-1)" "prognostic favourable (8.01e-6)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (3.04e-2)" "unprognostic (2.64e-1)" 13.9 12.6 11.7 16.7 18.6 29.7 14.5 24.8 14.1 18.4 12.6 15.5 21.4 9.7 20.2 20.6 14.4 12.8 12.7 10.8 13.4 9.5 10.3 11.4 13.0 12.1 17.7 9.4 18.8 18.4 18.8 18.9 38.0 12.6 14.0 11.8 12.6 15.8 22.9 30.3 25.2 13.1 13.6 16.0 14.6 14.9 13.6 19.6 22.6 16.9 9.3 16.8 17.8 31.6 5.6 3.5 16.1 3.9 5.5 2.9 0.6 9.5 4.8 9.0 9.5 16.2 9.8 10.5 5.0 3.8 4.0 4.9 9.1 5.8 15.2 7.3 9.1 5.5 9.6 7.3 6.7 9.6 4.9 9.0 7.2 6.3 7.9 15.3 11.1 8.2 10.1 5.7 7.6 5.7 14.5 13.2 8.7 13.3 11.0 13.9 5.4 4.8 7.4 8.1 7.9 6.9 9.9 13.1 10.3 8.2 14.7 5.4 4.8 12.5 7.2 6.7 3.5 7.1 7.1 13.8 6.7 16.4 8.7 12.5 6.8 8.8 3.5 4.3 2.1 2.2 2.9 5.6 1.7 1.7 1.7 3.8 2.7 1.8 16.1 5.5 3.9 3.5 1.3 0.6 11.7 18.6 24.8 14.1 13.4 9.5 17.7 9.4 12.6 19.6 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018975-49059774 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 5.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 12.1 7.6 4.9 6.7 10.8 26.1 6.8 11.7 10.5 9.5 6.5 5.8 13.0 5.5 15.7 7.4 8.8 8.9 5.8 9.1 6.1 3.5 6.2 6.5 22.9 9.6 6.7 3.3 9.7 11.6 13.3 9.2 12.9 13.7 6.7 6.6 9.8 7.6 8.0 16.1 13.6 9.4 7.1 9.1 13.6 8.3 7.3 5.7 6.2 11.0 6.1 7.6 7.0 6.3 2.0 2.2 5.9 0.5 1.5 0.8 0.6 17.0 16.2 16.4 13.2 17.0 11.4 17.6 9.0 9.4 11.7 6.3 28.4 7.2 17.7 11.7 12.6 11.6 21.6 10.0 9.8 10.3 17.3 22.5 16.9 15.2 11.7 26.7 22.6 9.7 14.3 16.4 17.0 17.4 28.2 9.8 13.2 18.7 13.2 24.9 15.5 14.0 19.9 10.1 6.4 9.8 18.9 13.7 11.6 13.9 13.7 9.5 13.6 23.4 23.1 9.2 16.5 8.1 15.1 14.0 9.0 17.2 10.6 13.8 6.9 0.6 0.5 3.0 0.8 0.2 0.4 0.3 0.3 0.5 0.3 2.0 0.3 0.8 5.9 1.5 0.1 2.2 0.0 0.6 4.9 10.8 11.7 10.5 6.1 3.5 6.7 3.3 13.7 5.7 KMT5A "PR-Set7, SET07, SET8, SETD8" ENSG00000183955 "Lysine methyltransferase 5A" Q9NQR1 12 123383773-123409358 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064495 Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA064495: " "unprognostic (5.62e-2)" "unprognostic (4.45e-2)" "unprognostic (3.90e-1)" "unprognostic (3.04e-1)" "unprognostic (2.20e-2)" "unprognostic (1.73e-1)" "prognostic unfavourable (6.21e-7)" "unprognostic (3.88e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-2)" "unprognostic (6.13e-2)" "unprognostic (3.44e-1)" "unprognostic (4.75e-3)" "unprognostic (4.27e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.06e-1)" 7.6 5.4 8.9 14.0 7.5 20.2 7.9 9.8 14.1 13.9 9.1 9.9 21.4 7.3 15.7 9.5 22.3 12.3 8.3 10.9 8.1 5.5 6.7 7.4 8.7 8.4 7.8 10.6 7.2 13.1 6.8 7.4 9.9 12.8 18.6 9.1 7.9 19.3 12.5 13.6 15.6 9.1 11.0 10.3 13.3 9.0 5.2 8.6 42.2 17.2 8.9 19.7 12.3 14.2 3.5 3.8 7.8 3.8 4.1 5.4 0.6 12.2 7.8 9.3 14.3 6.0 10.7 12.8 18.2 8.8 10.6 9.4 8.9 7.2 28.3 10.6 12.1 11.4 13.3 6.7 11.4 11.9 13.8 23.7 8.2 4.4 9.0 18.4 6.0 4.6 8.4 11.5 10.7 8.7 42.9 13.1 8.7 8.9 18.6 27.5 4.3 8.9 22.2 8.0 7.6 7.4 14.9 12.8 10.1 18.2 9.3 8.4 12.9 23.5 11.0 12.0 8.7 14.2 13.1 7.3 7.6 25.9 8.2 9.7 10.0 4.1 2.5 7.8 2.8 3.8 5.4 3.5 3.3 4.3 2.0 2.3 1.8 2.3 3.4 4.1 3.6 3.8 2.7 0.6 8.9 7.5 9.8 14.1 8.1 5.5 7.8 10.6 12.8 8.6 KMT5B "CGI-85, SUV420H1" ENSG00000110066 "Lysine methyltransferase 5B" Q4FZB7 11 68154863-68213828 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063648 Supported Nucleoplasm Nucleoplasm "HPA063648: " "unprognostic (5.82e-2)" "unprognostic (4.25e-2)" "unprognostic (2.54e-1)" "unprognostic (5.36e-3)" "unprognostic (3.52e-1)" "unprognostic (2.94e-1)" "unprognostic (1.83e-2)" "unprognostic (1.08e-1)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "unprognostic (5.54e-2)" "unprognostic (1.21e-1)" "unprognostic (3.79e-3)" "unprognostic (2.62e-1)" "unprognostic (4.26e-2)" "unprognostic (3.21e-2)" "prognostic favourable (9.30e-4)" 17.6 19.1 20.9 23.4 22.5 23.7 27.3 38.8 26.7 22.4 21.2 19.9 32.3 21.8 26.2 22.7 19.7 20.4 18.2 15.1 23.8 15.3 19.1 21.5 17.4 16.9 18.6 22.2 27.4 24.0 27.4 28.1 26.6 17.0 24.9 21.5 15.4 25.2 30.4 18.8 20.8 24.0 23.4 18.4 19.6 19.7 19.1 23.6 38.0 30.9 17.5 19.1 20.5 22.5 4.5 5.5 16.0 5.2 8.9 5.9 2.7 10.1 7.7 15.8 10.2 3.7 9.3 17.1 7.3 5.1 9.1 5.4 24.2 16.3 8.3 12.8 10.0 5.4 10.9 8.5 13.5 9.3 6.3 7.9 9.1 10.0 13.4 11.0 10.9 9.1 17.6 11.0 11.6 9.0 11.6 9.7 7.8 21.0 7.7 11.6 16.9 5.8 12.9 12.3 22.3 6.8 9.9 13.8 16.5 11.3 11.5 51.5 14.6 7.3 9.5 12.4 16.5 9.5 7.4 12.5 5.4 17.6 7.8 7.0 13.2 7.8 3.7 16.0 4.7 5.2 3.3 3.4 5.1 5.7 3.6 4.5 5.9 5.2 11.3 8.9 4.8 5.5 4.0 2.7 20.9 22.5 38.8 26.7 23.8 15.3 18.6 22.2 17.0 23.6 KMT5C "MGC2705, SUV420H2" ENSG00000133247 "Lysine methyltransferase 5C" Q86Y97 19 55339853-55348120 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 16.4;SCLC-21H: 16.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052294 Uncertain Approved Nucleoplasm Nucleoplasm "HPA052294: " "unprognostic (4.02e-2)" "unprognostic (3.45e-2)" "unprognostic (2.92e-3)" "unprognostic (6.77e-3)" "unprognostic (2.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.29e-2)" "unprognostic (1.27e-1)" "unprognostic (8.69e-2)" "unprognostic (3.04e-1)" "unprognostic (9.48e-3)" "unprognostic (1.49e-2)" "prognostic unfavourable (1.05e-8)" "unprognostic (7.39e-2)" "unprognostic (2.96e-1)" "unprognostic (9.41e-2)" "unprognostic (2.39e-2)" 5.0 5.6 8.5 7.3 15.7 13.4 5.4 20.0 10.7 5.1 7.5 11.2 4.9 11.9 7.0 5.4 4.6 11.0 7.4 4.2 11.2 4.5 5.1 4.4 5.5 4.6 17.1 5.3 6.1 8.5 6.2 11.7 6.5 9.6 6.6 3.8 6.3 7.7 6.3 6.6 13.5 8.5 3.6 6.2 6.2 9.8 7.0 14.7 10.1 5.1 2.3 3.5 6.3 4.6 0.3 0.8 0.9 0.6 1.1 0.8 0.3 4.9 3.5 3.3 2.7 0.7 0.9 9.2 1.4 0.6 0.5 1.3 2.2 4.2 4.9 1.8 1.1 2.7 2.1 1.8 0.6 4.4 16.4 3.9 2.5 2.2 1.2 2.3 4.7 0.8 2.4 1.6 0.9 1.1 9.6 2.8 0.6 5.7 6.5 5.1 5.9 5.1 9.7 3.8 4.8 0.8 1.2 16.0 6.8 0.7 3.7 2.0 4.1 2.9 1.2 1.6 4.0 0.5 1.0 8.1 4.0 3.1 0.8 5.5 2.2 0.3 0.6 0.3 0.7 0.4 0.0 0.1 0.5 0.7 0.6 0.3 0.3 0.8 0.9 1.1 0.0 0.8 0.2 0.3 8.5 15.7 20.0 10.7 11.2 4.5 17.1 5.3 9.6 14.7 KSR1 "KSR, RSU2" ENSG00000141068 "Kinase suppressor of ras 1" Q8IVT5 17 27456470-27626438 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 57.7" "Cell line enhanced" "Detected in many" "HDLM-2: 87.7;HEL: 31.5;HMC-1: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 7.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009623, HPA011215" Uncertain "CAB009623: AB_2265455, HPA011215: AB_1852649" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (2.60e-1)" "unprognostic (3.48e-3)" "unprognostic (2.90e-1)" "unprognostic (6.98e-2)" "unprognostic (1.92e-5)" "unprognostic (8.36e-3)" "unprognostic (1.32e-1)" "unprognostic (3.15e-2)" "unprognostic (1.12e-3)" "unprognostic (1.65e-1)" "prognostic unfavourable (6.54e-4)" "unprognostic (1.00e-1)" "unprognostic (7.55e-2)" "unprognostic (1.74e-2)" "unprognostic (9.61e-2)" 10.5 9.3 15.3 12.5 16.0 9.5 7.7 20.5 18.5 15.5 6.1 20.5 7.0 5.4 17.9 7.0 15.5 9.3 21.2 7.0 17.5 7.0 12.4 3.8 12.4 8.6 18.3 12.5 14.4 57.7 7.3 8.9 29.4 16.2 7.9 5.9 19.8 4.7 13.4 17.5 13.8 7.6 13.7 12.0 12.2 5.1 11.5 19.9 5.2 16.3 3.3 9.4 8.9 13.5 0.9 1.1 7.0 4.1 1.5 1.1 0.7 1.0 4.1 2.5 1.3 2.2 1.5 15.1 0.9 2.0 1.4 1.7 12.4 0.1 1.0 2.2 1.8 0.6 2.5 0.5 0.8 87.7 2.8 31.5 4.0 5.1 3.8 0.4 21.7 1.9 0.9 4.1 0.1 8.0 16.4 0.1 0.8 0.9 0.4 1.2 1.9 0.7 2.0 14.3 0.7 5.9 0.7 4.0 2.6 5.1 1.2 1.3 0.1 1.6 7.4 0.4 1.9 1.2 0.6 0.1 0.0 0.0 0.4 1.8 2.4 0.0 1.9 7.0 0.7 4.1 0.7 0.9 0.3 0.4 1.1 0.4 0.2 0.2 2.2 1.5 2.0 0.1 1.1 0.7 15.3 16.0 20.5 18.5 17.5 7.0 18.3 12.5 16.2 19.9 KSR2 FLJ25965 ENSG00000171435 "Kinase suppressor of ras 2" Q6VAB6 12 117453012-117968983 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 27.4;pituitary gland: 24.6" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 7.2;SCLC-21H: 5.3;TIME: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035536 Enhanced "HPA035536: AB_10673485" "unprognostic (1.74e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (2.29e-2)" "unprognostic (9.11e-2)" "unprognostic (8.42e-2)" "unprognostic (6.91e-3)" "unprognostic (1.10e-2)" "unprognostic (5.78e-2)" "unprognostic (5.80e-2)" "unprognostic (2.05e-4)" "unprognostic (1.19e-1)" "unprognostic (9.28e-3)" "unprognostic (5.02e-2)" "unprognostic (5.68e-2)" "unprognostic (8.14e-3)" "unprognostic (5.74e-2)" 0.9 5.0 13.2 1.1 13.8 1.1 1.7 27.4 17.2 1.0 1.9 1.3 2.2 1.0 0.8 2.6 0.9 1.7 1.0 0.8 12.9 4.8 3.5 0.8 1.2 1.6 2.2 10.8 0.8 3.0 0.9 24.6 0.9 7.7 1.3 2.3 0.2 1.2 3.4 0.9 1.0 1.0 0.9 2.9 1.0 1.7 3.2 3.0 0.0 3.8 0.0 1.5 2.3 0.5 0.1 0.2 0.8 0.1 0.2 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.1 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 1.5 0.1 0.0 0.5 1.2 0.0 0.0 0.1 0.7 1.4 5.3 0.1 0.0 0.0 0.0 1.1 0.0 10.8 0.0 0.8 0.0 0.2 0.9 1.5 0.0 0.4 0.0 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.2 0.1 0.2 0.0 0.0 13.2 13.8 27.4 17.2 12.9 4.8 2.2 10.8 7.7 3.0 KYAT1 "CCBL1, GTK, KATI" ENSG00000171097 "Kynurenine aminotransferase 1" Q16773 9 128832942-128882494 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021176, HPA021177, HPA027736" Approved Supported Cytosol 21000 Cytosol "HPA021176: AB_1846120, HPA021177: AB_1846119, HPA027736: AB_10611818" "unprognostic (6.51e-2)" "unprognostic (8.67e-3)" "unprognostic (1.05e-2)" "unprognostic (5.98e-3)" "unprognostic (2.15e-2)" "unprognostic (5.44e-2)" "unprognostic (2.91e-2)" "unprognostic (1.12e-2)" "unprognostic (2.47e-1)" "unprognostic (8.60e-3)" "unprognostic (1.43e-1)" "unprognostic (3.65e-2)" "unprognostic (3.10e-2)" "unprognostic (5.79e-2)" "unprognostic (2.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" 4.4 5.2 12.2 5.1 18.9 3.9 7.0 17.8 17.6 4.7 3.8 14.2 5.5 4.1 5.5 5.4 4.6 8.5 4.8 13.5 12.1 9.3 8.1 12.0 4.1 7.3 18.4 12.1 7.1 5.0 8.9 8.1 4.5 12.2 8.9 2.7 5.8 7.0 8.4 17.0 12.2 4.8 5.8 10.2 5.8 4.0 6.9 17.2 3.7 7.5 2.8 7.4 8.1 8.1 12.1 7.6 3.5 5.1 4.6 9.6 4.9 4.0 9.3 8.5 8.4 7.7 9.7 4.4 5.6 6.4 5.5 8.3 5.1 7.6 7.8 2.8 4.2 13.2 12.6 10.9 7.1 8.7 8.8 5.1 22.5 9.2 6.9 4.9 2.2 4.2 6.9 7.2 6.9 9.7 7.8 6.9 7.2 2.6 11.3 3.3 14.9 7.2 13.5 7.3 14.5 7.6 1.7 9.0 7.7 8.9 2.2 5.1 5.4 1.9 6.4 4.2 7.2 6.2 4.9 12.7 10.7 9.6 8.0 7.6 3.4 0.1 3.1 3.3 7.8 2.2 6.2 12.1 8.1 8.1 7.6 5.8 8.6 9.6 3.5 4.6 5.1 4.8 8.7 4.9 12.2 18.9 17.8 17.6 12.1 9.3 18.4 12.1 12.2 17.2 KYAT3 "CCBL2, KAT3, KATIII, RBM1, RP11-82K18.3" ENSG00000137944 "Kynurenine aminotransferase 3" Q6YP21 1 88935773-88992953 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026538, HPA027168" Enhanced Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA026538: AB_1852076, HPA027168: AB_1852078" "prognostic favourable (3.19e-5)" "unprognostic (3.36e-3)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (2.01e-2)" "prognostic favourable (1.86e-4)" "unprognostic (2.61e-1)" "unprognostic (3.61e-3)" "unprognostic (2.11e-1)" "prognostic favourable (2.80e-4)" "unprognostic (1.04e-1)" "unprognostic (3.17e-1)" "prognostic favourable (5.02e-6)" "unprognostic (1.17e-1)" "unprognostic (1.06e-1)" "unprognostic (2.51e-1)" "unprognostic (2.78e-1)" 22.2 26.8 16.6 13.2 19.3 10.6 27.5 14.9 23.5 23.7 17.5 20.0 13.0 19.4 24.1 21.2 27.2 18.9 17.8 13.2 18.6 14.2 27.3 23.8 17.1 17.6 16.9 22.2 27.4 28.6 27.0 19.5 21.9 23.4 19.0 19.6 19.5 21.0 20.7 10.4 22.0 17.2 22.1 14.8 20.7 23.5 15.6 17.2 15.5 24.5 13.4 20.2 25.2 17.7 9.6 17.0 9.2 12.7 11.5 16.7 8.2 20.4 4.3 20.9 7.0 7.5 21.0 18.2 12.6 23.7 16.1 21.0 6.2 7.2 13.5 9.6 9.3 5.8 5.9 9.7 24.7 7.9 8.4 12.1 4.1 10.3 24.6 16.9 3.3 17.7 9.8 11.0 20.0 15.6 15.5 7.1 15.1 6.7 18.0 8.2 12.5 3.8 18.4 14.7 7.2 33.9 20.9 15.3 18.6 16.7 22.3 10.9 12.3 4.1 10.4 6.8 4.5 21.6 9.1 9.6 4.8 9.0 3.3 7.5 5.7 5.6 12.7 7.1 9.1 7.9 12.6 9.6 11.8 10.5 17.0 9.3 12.4 10.4 9.2 11.5 10.2 6.3 16.7 8.2 16.6 19.3 14.9 23.5 18.6 14.2 16.9 22.2 23.4 17.2 KYNU ENSG00000115919 Kynureninase Q16719 2 142877498-143055832 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 35.9;liver: 41.1;placenta: 34.3" "Cell line enhanced" "Detected in some" "A549: 40.1;HeLa: 44.8;Hep G2: 27.2;hTEC/SVTERT24-B: 23.5;SiHa: 22.2;U-87 MG: 70.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 18 "classical monocyte: 28.7;intermediate monocyte: 35.9;memory B-cell: 19.7;myeloid DC: 28.4;naive B-cell: 12.7;non-classical monocyte: 29.2;plasmacytoid DC: 19.9" "Group enriched" "Detected in many" 21 "B-cells: 19.7;dendritic cells: 28.4;monocytes: 35.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA031686 Enhanced Supported Nucleoplasm,Cytosol 360000 Cytosol Nucleoplasm "HPA031686: " "unprognostic (2.58e-2)" "unprognostic (3.39e-3)" "unprognostic (1.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.36e-3)" "unprognostic (3.58e-3)" "unprognostic (4.88e-2)" "unprognostic (3.35e-2)" "unprognostic (2.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-3)" "unprognostic (3.65e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-1)" 9.0 3.7 2.2 11.0 3.7 3.9 15.4 0.6 1.7 3.0 1.2 1.3 0.8 0.2 1.1 2.6 5.6 1.5 4.4 3.8 1.4 1.1 8.4 41.1 12.7 13.7 2.9 0.4 1.7 1.0 0.2 1.6 34.3 2.7 1.9 1.2 1.5 3.0 0.8 0.7 1.5 2.7 2.0 6.3 16.0 2.4 7.0 2.6 2.7 2.2 1.7 13.0 12.4 2.6 19.7 28.4 1.3 35.9 0.4 0.1 11.1 0.0 40.1 0.1 0.1 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.7 0.5 2.4 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 44.8 27.2 0.5 0.1 0.2 3.9 3.2 23.5 0.1 0.0 0.1 0.2 0.3 20.5 0.0 2.4 0.1 0.1 0.0 0.2 0.1 0.6 20.7 0.1 0.0 22.2 3.3 0.2 11.1 5.7 0.3 1.3 0.1 19.6 0.0 0.1 0.0 0.0 70.2 4.6 0.1 0.1 28.7 0.5 0.1 35.9 0.1 19.7 0.1 0.1 28.4 12.7 0.1 0.0 1.3 0.4 29.2 19.9 0.1 11.1 2.2 3.7 0.6 1.7 1.4 1.1 2.9 0.4 2.7 2.6 L2HGDH "C14orf160, FLJ12618" ENSG00000087299 "L-2-hydroxyglutarate dehydrogenase" Q9H9P8 14 50237563-50312548 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 10.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065409, HPA069708" Approved Enhanced Mitochondria Mitochondria "HPA065409: , HPA069708: " "unprognostic (1.74e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (1.23e-3)" "unprognostic (1.04e-2)" "unprognostic (4.33e-2)" "unprognostic (8.84e-2)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (9.91e-2)" "unprognostic (2.84e-1)" "unprognostic (1.97e-1)" "prognostic favourable (9.75e-10)" "unprognostic (1.24e-2)" "unprognostic (5.88e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-2)" 5.4 5.1 6.9 3.6 8.4 3.5 5.1 12.7 10.9 3.5 5.6 4.9 4.8 6.2 3.4 4.3 9.0 4.4 3.2 7.7 6.1 4.7 25.5 16.0 2.5 3.3 7.7 4.7 4.2 5.4 7.1 5.8 2.6 5.7 4.6 6.8 7.7 5.0 5.6 17.7 7.0 5.0 4.7 5.3 2.3 5.6 6.0 6.0 3.7 6.5 6.2 5.2 4.6 4.4 1.4 1.5 10.5 0.6 2.4 3.3 0.8 13.8 9.8 4.0 3.9 2.0 1.3 11.4 4.6 2.6 7.3 8.7 15.6 6.4 10.9 5.4 1.8 10.2 12.1 4.8 8.2 8.7 6.9 23.7 6.7 2.1 1.9 8.3 8.2 1.2 3.1 4.8 4.2 3.1 8.3 6.9 1.9 16.7 9.4 3.8 5.9 10.4 8.9 13.2 8.5 6.8 16.3 8.3 5.9 13.6 10.4 5.9 13.6 2.3 2.9 4.6 13.1 5.3 6.1 6.3 14.3 15.4 2.6 4.2 5.2 10.5 0.6 1.4 1.5 0.3 3.3 1.4 1.7 1.6 0.9 1.2 2.1 2.6 0.9 2.4 0.3 1.5 2.4 0.8 6.9 8.4 12.7 10.9 6.1 4.7 7.7 4.7 5.7 6.0 L3HYPDH "C14orf149, FLJ25436" ENSG00000126790 "Trans-L-3-hydroxyproline dehydratase" Q96EM0 14 59460363-59484430 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056694 Approved Uncertain Vesicles 16000 Vesicles "HPA056694: " "unprognostic (3.39e-2)" "unprognostic (5.55e-3)" "unprognostic (3.81e-2)" "unprognostic (5.86e-2)" "unprognostic (1.10e-1)" "unprognostic (5.06e-2)" "unprognostic (8.34e-2)" "unprognostic (1.16e-1)" "unprognostic (7.24e-2)" "unprognostic (9.50e-2)" "unprognostic (1.26e-3)" "unprognostic (6.60e-2)" "prognostic unfavourable (1.72e-9)" "unprognostic (1.16e-1)" "unprognostic (2.22e-1)" "unprognostic (1.05e-1)" "unprognostic (1.14e-1)" 17.9 15.4 13.5 13.5 17.1 4.9 22.8 10.4 16.5 12.6 9.9 18.5 10.9 12.3 17.6 10.3 9.8 16.3 13.2 15.9 13.6 7.2 20.2 17.4 11.5 18.5 22.7 9.6 20.1 12.8 23.1 22.5 11.9 18.2 15.5 12.0 12.9 13.6 15.5 8.7 11.0 13.7 14.0 18.4 14.3 11.0 18.9 17.4 6.6 17.9 9.9 15.0 12.7 18.7 2.3 7.9 0.8 7.0 7.0 5.1 2.5 6.1 16.6 3.6 8.5 7.8 20.7 5.1 16.6 13.2 9.6 9.4 3.3 11.1 2.1 7.0 9.2 16.7 5.8 8.9 9.5 3.5 7.5 5.7 14.5 12.0 8.9 5.0 4.1 14.9 6.1 9.6 14.9 11.7 7.4 9.8 9.9 7.3 1.9 8.3 5.8 15.0 2.8 5.9 8.4 15.4 3.5 3.7 5.3 15.6 6.5 5.9 6.8 3.3 16.3 11.3 13.7 8.7 19.4 2.5 1.1 2.0 19.4 4.3 21.9 0.0 5.0 0.8 5.1 7.0 3.4 2.3 2.5 3.0 7.9 2.2 3.9 1.4 0.0 7.0 3.2 4.3 1.1 2.5 13.5 17.1 10.4 16.5 13.6 7.2 22.7 9.6 18.2 17.4 LACTB "FLJ14902, MRPL56" ENSG00000103642 "Lactamase beta" P83111 15 63121800-63142061 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protease" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036361, HPA036362" Supported Supported Mitochondria "Intracellular and membrane" Mitochondria "HPA036361: AB_10672244, HPA036362: AB_10670798" "unprognostic (6.07e-2)" "unprognostic (2.02e-1)" "unprognostic (2.22e-2)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (3.10e-2)" "unprognostic (8.08e-2)" "unprognostic (6.25e-2)" "unprognostic (8.98e-2)" "unprognostic (3.08e-1)" "unprognostic (6.22e-3)" "unprognostic (5.16e-3)" "unprognostic (6.28e-2)" "unprognostic (3.24e-1)" "unprognostic (8.64e-2)" "unprognostic (7.90e-2)" "unprognostic (3.88e-3)" 26.5 22.7 9.2 13.1 12.2 31.5 9.3 7.3 9.1 6.8 11.4 6.3 4.0 12.5 7.0 6.9 9.8 5.7 9.2 24.9 7.9 6.1 20.5 38.3 18.8 12.9 8.5 6.1 7.2 9.3 6.7 10.4 7.4 9.5 7.6 10.4 5.8 9.3 4.7 37.3 10.1 19.6 8.1 8.0 21.6 8.3 13.2 9.8 8.3 8.4 11.1 9.0 11.5 12.8 3.3 10.4 5.8 8.9 2.3 3.1 2.0 21.4 13.5 3.8 2.6 19.5 10.5 3.2 9.4 14.5 16.2 30.2 3.4 13.8 2.8 11.6 13.6 6.0 13.1 6.1 20.3 19.7 3.2 5.5 4.6 8.4 18.2 5.0 9.6 14.2 13.0 16.6 13.7 16.6 5.2 8.2 27.3 8.1 3.8 6.0 5.8 4.2 2.8 9.9 6.5 8.7 33.6 3.5 1.6 6.8 7.7 20.2 5.8 8.2 29.7 21.8 17.1 9.8 11.8 8.6 7.5 0.7 16.7 14.1 10.0 3.6 8.8 4.6 1.3 8.9 2.0 3.3 1.1 1.0 10.4 2.9 1.0 1.6 5.8 2.3 7.6 0.9 3.1 2.0 9.2 12.2 7.3 9.1 7.9 6.1 8.5 6.1 9.5 9.8 LAP3 "LAP, LAPEP, PEPS" ENSG00000002549 "Leucine aminopeptidase 3" P28838 4 17577192-17607972 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029606, HPA029607" Enhanced Supported Nucleoplasm,Midbody,Cytosol 4100000 Cytosol "Nucleoplasm, Midbody" "HPA029606: AB_10599288, HPA029607: AB_10611381" "unprognostic (2.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (2.87e-1)" "unprognostic (2.16e-1)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.44e-3)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (4.29e-3)" "unprognostic (1.73e-1)" "unprognostic (3.28e-2)" "unprognostic (3.06e-1)" "unprognostic (8.79e-2)" 42.5 29.7 23.2 43.9 38.5 18.1 30.7 8.5 23.5 13.3 21.0 23.5 12.3 27.5 17.2 20.8 19.3 18.7 24.3 25.4 24.4 17.0 71.7 70.3 39.4 54.2 33.7 16.1 13.5 14.7 23.5 13.2 25.0 34.9 15.3 22.7 15.0 23.0 12.1 33.3 20.9 30.6 26.9 35.0 54.9 20.8 19.3 30.7 19.9 29.4 21.7 32.1 24.4 23.7 7.5 45.7 9.5 46.1 11.8 12.9 25.3 10.8 9.5 9.1 8.6 18.1 22.1 0.1 17.1 19.3 62.3 75.7 17.3 20.7 42.7 11.4 13.1 6.7 34.2 12.1 23.7 16.3 9.8 23.7 10.5 22.6 21.1 21.3 15.2 22.4 7.7 20.4 10.7 21.6 22.9 30.5 14.6 11.7 18.9 29.2 19.0 18.2 29.4 8.7 21.6 16.2 12.7 13.5 11.1 15.7 9.7 33.5 8.2 8.2 14.0 15.8 10.7 16.6 29.7 28.1 42.9 36.9 21.4 35.5 15.3 8.4 43.4 9.5 8.0 46.1 7.4 7.5 7.5 8.5 45.7 5.2 6.5 6.8 6.2 11.8 31.9 25.9 12.9 25.3 23.2 38.5 8.5 23.5 24.4 17.0 33.7 16.1 34.9 30.7 LARS "FLJ10595, FLJ21788, HSPC192, LARS1, LEUS, RNTLS" ENSG00000133706 "Leucyl-tRNA synthetase" Q9P2J5 5 146113038-146182660 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036424, HPA040881" Supported Enhanced "Nuclear bodies,Cytosol" 14000 "Nuclear bodies, Cytosol" "HPA036424: AB_10670102, HPA040881: " "unprognostic (2.20e-2)" "unprognostic (1.87e-1)" "unprognostic (2.38e-3)" "unprognostic (1.92e-1)" "unprognostic (2.69e-1)" "unprognostic (3.39e-1)" "prognostic unfavourable (3.78e-5)" "unprognostic (8.17e-2)" "unprognostic (2.72e-1)" "unprognostic (6.80e-2)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-1)" "unprognostic (1.29e-1)" "prognostic unfavourable (2.98e-4)" "unprognostic (2.96e-2)" 32.2 30.1 27.0 25.8 31.2 17.8 38.6 31.8 33.7 25.5 25.3 30.1 23.9 16.8 35.8 31.3 28.5 26.8 16.4 29.0 24.2 22.2 26.5 18.4 20.0 24.8 27.3 26.1 32.0 40.8 35.0 43.0 20.6 31.6 26.3 29.9 19.5 39.9 24.8 55.5 24.1 21.5 32.5 30.9 25.2 24.9 20.5 30.5 25.6 30.8 22.8 28.9 30.9 29.2 21.3 28.0 5.8 18.3 19.0 21.8 11.2 20.4 24.2 28.0 45.9 23.2 30.3 43.6 23.9 17.7 24.2 35.1 25.2 22.4 31.1 14.8 31.4 17.5 47.3 39.3 42.4 26.7 27.8 35.5 30.6 14.6 32.2 50.4 23.5 23.8 39.6 39.6 68.8 33.0 39.4 58.3 26.0 16.9 38.9 30.9 43.4 26.8 30.1 35.3 31.0 18.5 18.5 27.6 34.8 26.0 28.7 60.4 32.6 43.5 32.2 28.3 18.8 25.6 35.7 30.3 44.7 50.9 30.8 53.2 33.0 2.5 13.5 5.8 14.8 18.3 19.8 21.1 16.4 13.6 18.6 21.3 21.8 18.0 1.2 19.0 13.6 28.0 14.8 11.2 27.0 31.2 31.8 33.7 24.2 22.2 27.3 26.1 31.6 30.5 LARS2 "KIAA0028, LEURS, MGC26121, mtLeuRS" ENSG00000011376 "Leucyl-tRNA synthetase 2, mitochondrial" Q15031 3 45388506-45549421 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035951, HPA045450, HPA066085" Approved Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA035951: AB_10672997, HPA045450: , HPA066085: " "unprognostic (3.89e-1)" "unprognostic (3.89e-1)" "prognostic favourable (1.71e-4)" "unprognostic (3.02e-2)" "unprognostic (3.77e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-3)" "unprognostic (9.19e-2)" "unprognostic (6.13e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-1)" "unprognostic (4.37e-2)" "prognostic favourable (1.32e-11)" "unprognostic (2.81e-1)" "unprognostic (5.74e-2)" "unprognostic (9.90e-2)" "unprognostic (9.07e-2)" 9.6 14.3 18.8 9.6 21.8 6.7 8.1 11.9 17.9 9.2 14.8 13.1 8.3 9.6 9.8 8.9 10.4 11.2 8.4 14.2 14.6 13.6 18.9 17.2 7.0 10.3 15.7 9.5 10.2 8.2 20.0 14.0 10.6 12.3 10.8 15.3 10.0 8.7 9.8 14.1 7.8 8.8 11.0 8.8 10.0 8.9 7.3 11.8 16.1 10.5 8.3 12.8 11.3 7.8 5.1 5.9 2.4 3.3 8.4 6.0 3.7 6.2 7.9 9.2 8.7 8.4 9.5 9.9 9.8 10.1 18.3 13.7 14.0 8.8 13.0 8.4 11.4 6.8 34.2 20.5 13.9 11.4 8.6 14.1 12.8 13.5 8.8 20.4 5.2 12.3 12.7 17.5 9.2 11.4 21.9 7.4 11.4 6.9 14.6 7.5 23.0 14.6 8.3 9.2 14.5 16.3 15.2 7.3 9.1 15.6 8.8 8.1 14.0 12.0 10.0 11.2 8.3 9.3 11.7 5.8 10.6 13.9 13.2 13.9 9.9 0.6 2.8 2.4 6.0 3.3 5.8 5.1 4.4 5.4 5.9 4.0 4.8 5.4 1.2 8.4 3.0 4.5 3.9 3.7 18.8 21.8 11.9 17.9 14.6 13.6 15.7 9.5 12.3 11.8 LATS1 WARTS ENSG00000131023 "Large tumor suppressor kinase 1" O95835 6 149658153-149718256 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031804 Approved Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA031804: AB_10601688" "unprognostic (4.02e-3)" "unprognostic (3.80e-3)" "unprognostic (1.28e-2)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (2.09e-1)" "unprognostic (6.15e-3)" "unprognostic (1.29e-2)" "unprognostic (9.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (5.62e-2)" "unprognostic (1.92e-1)" "unprognostic (8.43e-2)" "unprognostic (2.63e-1)" "unprognostic (2.65e-1)" 15.4 12.9 17.6 12.5 17.6 19.4 14.7 38.4 16.9 15.9 13.6 17.4 9.5 10.1 17.7 11.8 12.2 14.6 11.1 11.7 15.1 8.8 11.5 11.1 12.7 12.6 18.2 8.8 23.6 12.2 22.3 21.8 17.2 15.5 16.3 12.5 14.1 13.8 11.9 12.4 12.8 14.7 15.8 13.0 13.5 11.6 10.6 19.6 20.5 12.9 6.5 12.8 14.7 14.7 7.4 4.6 9.5 11.4 4.2 8.9 2.9 6.1 4.8 10.2 14.4 9.6 12.6 7.8 8.1 8.2 8.8 8.8 7.8 5.3 9.9 8.3 11.3 8.6 13.3 8.7 13.9 9.1 10.6 20.0 6.1 7.0 8.9 18.7 14.6 8.4 14.0 9.9 17.0 10.9 24.6 10.2 8.6 7.3 9.7 7.7 6.0 4.7 9.5 12.2 4.6 8.1 8.7 6.8 10.9 11.4 8.3 6.0 8.6 16.2 13.4 7.0 11.0 8.3 13.0 8.5 9.3 11.4 6.4 10.6 10.3 9.5 4.2 6.6 8.9 7.7 8.0 5.8 7.0 7.4 4.6 7.4 6.0 7.8 2.9 4.2 11.4 4.1 6.7 2.9 17.6 17.6 38.4 16.9 15.1 8.8 18.2 8.8 15.5 19.6 LATS2 ENSG00000150457 "Large tumor suppressor kinase 2" Q9NRM7 13 20973032-21061547 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039191, HPA049037" Approved Supported "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "HPA039191: , HPA049037: " "unprognostic (2.77e-1)" "prognostic unfavourable (3.26e-4)" "unprognostic (6.22e-3)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (1.84e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-3)" "unprognostic (4.48e-1)" "unprognostic (6.57e-3)" "unprognostic (8.03e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (1.66e-2)" "unprognostic (1.25e-1)" "unprognostic (7.97e-2)" "unprognostic (1.11e-2)" 22.9 13.0 3.0 8.6 5.7 12.8 33.0 7.9 3.7 16.6 14.0 6.8 9.3 2.9 21.2 12.7 15.1 11.0 20.6 14.1 5.4 2.6 12.4 11.0 19.8 10.9 5.2 2.4 17.4 10.2 5.0 3.5 18.3 6.3 13.7 4.5 16.7 8.0 11.1 23.0 9.3 7.4 34.6 7.5 15.2 10.4 27.8 5.2 1.4 17.2 13.8 7.0 20.3 28.0 0.1 1.5 3.3 1.9 1.3 3.1 0.5 3.3 3.7 8.3 5.0 9.8 12.9 7.6 11.2 11.7 11.8 10.1 10.6 5.1 0.0 5.5 17.1 4.9 4.9 5.1 17.5 1.9 1.2 6.2 4.7 7.9 15.3 1.6 2.2 19.1 9.4 7.7 5.2 16.4 1.1 0.2 14.8 5.8 0.1 5.8 2.0 1.8 1.4 14.8 0.0 8.4 1.6 0.1 0.0 8.8 5.8 11.6 5.0 3.2 20.6 12.5 8.4 9.1 7.1 1.5 0.8 0.0 3.0 1.9 9.5 0.4 1.9 1.8 1.6 1.5 3.1 0.1 0.2 0.5 1.5 0.0 0.1 0.3 3.3 1.3 0.6 0.1 0.0 0.5 3.0 5.7 7.9 3.7 5.4 2.6 5.2 2.4 6.3 5.2 LCAT ENSG00000213398 "Lecithin-cholesterol acyltransferase" P04180 16 67939750-67944131 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "Corneal dystrophy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 64.4;liver: 154.2" "Cell line enhanced" "Detected in many" "BEWO: 35.1;Hep G2: 27.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 64.4" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044767 Approved Nucleoplasm "Secreted to blood" 6470000000 9500000000 Nucleoplasm "HPA044767: AB_2756312" "unprognostic (3.34e-2)" "unprognostic (3.56e-2)" "prognostic unfavourable (8.50e-4)" "unprognostic (5.43e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-1)" "prognostic favourable (4.21e-8)" "unprognostic (6.42e-2)" "unprognostic (4.26e-1)" "unprognostic (4.12e-1)" "unprognostic (1.50e-2)" "unprognostic (7.21e-2)" "prognostic unfavourable (1.71e-4)" "unprognostic (9.93e-2)" "unprognostic (1.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.90e-3)" 4.4 3.6 6.3 2.2 3.7 0.9 4.3 64.4 9.6 4.5 4.4 7.3 1.4 1.3 5.3 3.0 1.8 3.5 3.5 4.5 8.4 1.8 3.9 154.2 5.6 1.9 5.5 6.3 4.7 2.5 5.9 2.7 5.5 9.2 6.4 1.3 1.8 2.4 6.2 3.4 9.9 2.4 3.8 7.5 3.9 2.3 2.2 6.1 1.4 7.6 1.6 1.4 2.6 4.5 1.8 0.8 5.0 1.1 1.3 1.4 0.1 2.4 4.0 5.9 6.7 5.2 7.3 35.1 9.8 4.2 6.6 4.7 13.1 3.0 1.3 1.8 14.1 8.7 1.4 13.4 4.1 0.6 3.6 1.7 8.7 27.3 7.1 0.3 4.7 12.6 12.8 13.7 4.8 4.8 3.7 0.5 4.7 4.0 1.6 4.2 3.9 2.2 1.7 6.5 1.4 1.8 4.3 0.2 3.0 14.8 0.7 1.6 8.4 2.6 9.2 8.6 13.4 9.4 3.5 8.1 2.1 3.7 4.1 1.1 7.4 2.4 1.1 5.0 0.9 0.1 1.3 1.2 0.7 0.8 0.2 1.8 1.4 0.4 2.8 1.3 0.5 0.8 0.0 0.1 6.3 3.7 64.4 9.6 8.4 1.8 5.5 6.3 9.2 6.1 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "blood: 112.2;lymphoid tissue: 153.0" "Group enriched" "Detected in some" 6 "MOLT-4: 98.9;U-698: 57.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "gdT-cell: 83.4;MAIT T-cell: 77.5;memory CD4 T-cell: 86.1;memory CD8 T-cell: 90.2;naive CD4 T-cell: 97.0;naive CD8 T-cell: 91.3;NK-cell: 42.8;T-reg: 112.2" "Group enriched" "Detected in many" 13 "NK-cells: 42.8;T-cells: 112.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favourable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favourable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favourable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavourable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 2.6 0.7 0.4 28.2 0.5 3.8 1.3 0.3 0.5 1.7 3.9 0.5 0.9 2.2 1.1 4.5 2.3 1.6 3.8 1.0 0.4 0.4 3.0 2.3 6.6 34.9 0.9 0.5 1.2 0.8 0.0 0.8 0.7 0.6 2.2 1.9 1.3 8.4 1.3 0.9 1.0 16.5 0.7 1.0 28.9 3.5 0.7 0.5 153.0 2.9 1.5 27.1 5.8 2.1 6.1 0.5 2.5 0.3 42.8 112.2 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 12.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.9 0.0 1.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 57.0 0.0 0.0 0.0 0.6 0.3 0.4 83.4 0.3 77.5 4.0 86.1 90.2 0.3 6.1 97.0 91.3 2.5 42.8 0.3 0.5 112.2 109.3 0.4 0.5 0.3 0.5 0.4 0.4 0.9 0.5 0.6 0.5 LCLAT1 "AGPAT8, ALCAT1, FLJ37965, LYCAT" ENSG00000172954 "Lysocardiolipin acyltransferase 1" Q6UWP7 2 30447226-30644225 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031880, HPA049217" Uncertain Supported "Endoplasmic reticulum,Cytosol" "Endoplasmic reticulum" Cytosol "HPA031880: AB_10610002, HPA049217: " "unprognostic (6.60e-2)" "unprognostic (2.47e-1)" "unprognostic (1.12e-1)" "unprognostic (9.52e-3)" "unprognostic (4.10e-1)" "prognostic unfavourable (9.67e-4)" "prognostic unfavourable (8.72e-4)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-2)" "unprognostic (7.11e-3)" "unprognostic (2.85e-2)" "unprognostic (4.14e-2)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (3.93e-3)" "unprognostic (1.10e-1)" 7.7 9.7 7.0 13.7 8.7 12.3 7.1 10.2 10.1 11.6 10.7 5.2 12.6 15.7 18.7 15.0 13.0 9.9 12.6 21.7 7.5 9.2 15.2 13.8 10.0 12.5 6.1 6.0 15.4 16.7 10.8 21.8 5.7 7.0 10.7 10.6 9.7 9.5 16.3 10.9 9.4 25.0 11.3 5.5 8.0 8.4 12.1 4.2 20.7 17.9 11.9 11.7 9.1 10.4 9.6 2.8 10.5 3.9 4.1 12.6 2.8 10.9 14.6 7.9 13.3 1.8 4.2 11.2 8.0 7.9 8.5 7.2 14.6 13.0 7.1 7.4 12.3 12.5 26.0 10.7 8.4 8.9 8.9 13.0 9.1 14.1 8.4 18.4 10.0 3.2 8.5 9.0 12.5 5.9 11.9 6.8 6.5 8.5 10.5 10.9 8.6 8.4 10.3 15.8 14.5 6.7 16.2 9.2 14.2 17.8 11.9 10.3 8.6 6.3 6.7 15.5 12.8 8.2 12.5 4.9 10.2 16.0 15.8 13.5 11.8 10.5 2.5 4.8 5.6 3.9 6.6 7.5 8.7 7.1 2.8 9.6 12.6 12.1 7.4 4.1 3.5 2.2 4.0 2.8 7.0 8.7 10.2 10.1 7.5 9.2 6.1 6.0 7.0 4.2 LCMT1 "CGI-68, PPMT1" ENSG00000205629 "Leucine carboxyl methyltransferase 1" Q9UIC8 16 25111729-25178231 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041559, HPA043530" Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA041559: , HPA043530: " "unprognostic (9.08e-2)" "prognostic favourable (2.78e-4)" "unprognostic (1.18e-1)" "unprognostic (3.71e-1)" "unprognostic (3.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavourable (5.85e-4)" "unprognostic (1.41e-2)" "unprognostic (7.41e-2)" "unprognostic (4.45e-2)" "unprognostic (4.62e-2)" "unprognostic (1.16e-1)" "prognostic favourable (7.53e-6)" "unprognostic (1.23e-1)" "unprognostic (8.99e-2)" "unprognostic (1.84e-3)" "unprognostic (6.71e-2)" 9.8 18.0 27.9 11.6 30.6 13.9 18.1 27.5 36.4 15.4 17.1 15.5 17.5 13.1 16.2 26.7 13.4 16.8 14.1 25.3 22.8 27.5 17.8 7.5 10.8 11.9 21.7 26.7 23.8 31.4 25.3 20.5 18.9 24.8 15.7 17.2 15.0 14.4 18.3 31.6 16.5 12.7 15.1 18.9 10.1 12.6 29.8 14.4 16.9 15.5 14.3 15.3 11.7 12.1 19.7 17.6 21.6 18.9 15.8 38.9 19.5 16.8 15.9 14.9 20.5 13.4 19.6 15.3 10.6 17.5 15.5 20.4 20.1 15.5 10.3 15.2 16.0 8.7 15.4 14.5 21.0 10.5 23.4 5.5 16.2 32.5 30.5 13.3 9.2 22.1 16.1 17.6 18.4 14.1 8.8 13.6 17.0 43.1 15.8 25.5 22.7 16.5 18.8 13.6 20.0 17.5 11.9 24.3 15.1 12.6 19.6 24.1 19.9 6.1 8.3 15.4 10.8 10.0 10.4 17.7 17.9 10.9 18.9 11.6 11.3 12.7 18.9 21.6 20.6 16.7 22.6 19.7 25.6 22.3 17.6 14.3 23.1 21.1 7.4 15.8 17.5 9.1 38.9 19.5 27.9 30.6 27.5 36.4 22.8 27.5 21.7 26.7 24.8 14.4 LCMT2 "KIAA0547, MGC9534, PPM2, TYW4" ENSG00000168806 "Leucine carboxyl methyltransferase 2" O60294 15 43323649-43330605 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039401, HPA048176" Approved Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA039401: AB_10805478, HPA048176: " "unprognostic (4.32e-2)" "unprognostic (1.44e-1)" "unprognostic (1.55e-1)" "unprognostic (4.11e-2)" "unprognostic (1.99e-1)" "unprognostic (2.27e-1)" "unprognostic (9.08e-2)" "unprognostic (5.14e-2)" "unprognostic (3.52e-2)" "unprognostic (2.20e-1)" "unprognostic (3.33e-3)" "unprognostic (9.57e-2)" "prognostic favourable (5.69e-9)" "unprognostic (2.28e-1)" "unprognostic (3.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.57e-1)" 7.9 10.9 6.5 8.3 8.1 2.5 25.9 11.4 10.1 10.8 7.4 7.2 10.6 5.2 10.3 12.7 11.0 10.2 6.7 8.4 6.7 8.4 11.9 9.2 6.2 9.9 6.1 7.6 13.0 8.2 13.7 10.1 6.4 9.6 10.2 7.5 8.9 10.3 13.8 7.9 6.2 8.4 8.6 4.8 9.6 8.7 7.1 9.6 12.2 9.8 11.2 13.9 7.4 9.6 6.3 6.9 5.5 4.0 3.3 10.5 5.0 6.0 4.8 11.3 9.8 12.1 3.7 5.5 7.4 8.9 9.7 10.7 7.1 2.8 5.1 15.2 8.4 14.3 0.0 9.8 7.4 7.9 5.2 9.2 12.9 4.1 7.4 0.0 6.9 5.8 9.5 7.2 6.6 3.1 11.6 6.9 11.6 9.4 10.3 4.3 4.9 4.0 12.2 10.0 5.0 16.9 6.9 15.2 12.9 9.8 8.3 4.2 10.1 14.1 2.6 11.4 5.2 13.0 12.0 4.7 11.0 2.1 7.1 7.6 11.8 2.4 4.0 5.5 4.0 3.8 5.5 5.0 6.7 4.8 6.9 6.3 10.5 6.8 1.3 3.3 3.5 3.9 5.3 5.0 6.5 8.1 11.4 10.1 6.7 8.4 6.1 7.6 9.6 9.6 LDHA ENSG00000134333 "Lactate dehydrogenase A" P00338 11 18394388-18408425 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease mutation, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 249.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015336, CAB069404" Uncertain Supported Vesicles,Cytosol 300000000 Cytosol Vesicles "CAB015336: AB_2134947, CAB069404: " "unprognostic (8.83e-2)" "prognostic unfavourable (2.78e-5)" "unprognostic (3.81e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (4.66e-3)" "prognostic unfavourable (3.26e-8)" "prognostic unfavourable (2.27e-6)" "unprognostic (1.08e-1)" "unprognostic (1.88e-2)" "prognostic unfavourable (8.09e-6)" "unprognostic (1.76e-2)" "prognostic unfavourable (9.69e-9)" "unprognostic (4.15e-2)" "unprognostic (1.89e-1)" "unprognostic (3.07e-1)" "unprognostic (1.05e-2)" 84.2 56.4 24.5 52.6 32.5 64.0 56.0 22.3 40.2 38.1 53.5 13.5 9.1 60.5 24.9 36.2 77.7 29.0 31.6 59.4 24.4 33.0 100.1 249.1 37.1 59.4 29.7 25.7 49.7 34.1 10.5 16.4 49.7 44.3 33.3 51.2 45.9 46.3 37.0 199.6 70.2 128.3 50.7 35.5 45.0 31.2 25.9 23.9 45.0 56.4 90.6 60.1 81.9 44.8 27.6 76.5 29.1 61.2 32.8 52.2 72.1 131.7 82.0 3.1 46.2 72.2 49.3 44.0 127.5 135.5 112.0 166.7 36.6 21.7 99.7 41.9 128.8 106.6 82.0 195.4 242.9 34.0 48.5 34.5 74.9 62.8 17.8 85.1 25.9 49.2 90.1 44.0 44.1 66.1 48.6 48.0 131.1 34.9 70.0 53.9 19.8 102.6 45.4 32.7 83.5 178.0 30.6 24.6 30.4 69.1 57.0 23.6 26.8 20.3 59.5 140.3 50.9 122.1 1.5 38.2 55.9 95.9 200.8 44.1 47.2 28.9 53.1 29.1 38.1 61.2 42.6 27.6 50.2 40.1 76.5 19.2 32.8 33.3 18.1 32.8 59.5 25.8 52.2 72.1 24.5 32.5 22.3 40.2 24.4 33.0 29.7 25.7 44.3 23.9 LDHAL6B "LDH6B, LDHAL6, LDHL" ENSG00000171989 "Lactate dehydrogenase A like 6B" Q9BYZ2 15 59206823-59208515 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "testis: 56.6" "Cell line enhanced" "Detected in some" "A549: 1.1;CAPAN-2: 1.5;HaCaT: 1.6;HeLa: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "olfactory region: 1.7" HPA053962 Enhanced "HPA053962: " "unprognostic (1.59e-1)" "unprognostic (9.41e-2)" "unprognostic (2.37e-1)" "unprognostic (4.46e-2)" "unprognostic (6.59e-2)" "unprognostic (2.23e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-1)" "unprognostic (2.29e-1)" "unprognostic (1.66e-1)" "unprognostic (5.13e-3)" "unprognostic (1.64e-1)" "unprognostic (3.12e-7)" "unprognostic (3.47e-2)" "unprognostic (1.49e-2)" "unprognostic (8.53e-2)" "unprognostic (7.80e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.8 0.0 0.4 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 1.5 0.4 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.4 0.4 0.7 0.3 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 LDHB ENSG00000111716 "Lactate dehydrogenase B" P07195 12 21635342-21757857 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 255.8;kidney: 233.1" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 318.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "T-cells: 145.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004641, HPA019007" Enhanced Supported Cytosol 780000000 Cytosol "CAB004641: AB_425525, HPA019007: " "unprognostic (2.93e-1)" "unprognostic (9.20e-3)" "unprognostic (6.10e-2)" "unprognostic (1.11e-1)" "unprognostic (5.39e-3)" "unprognostic (1.36e-3)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (5.34e-2)" "unprognostic (8.40e-2)" "unprognostic (2.91e-1)" "unprognostic (6.41e-2)" "prognostic favourable (2.51e-4)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (2.55e-1)" "unprognostic (9.32e-2)" 70.9 60.2 79.5 33.3 79.6 40.8 33.4 52.4 80.1 24.9 31.8 30.6 13.2 11.8 38.7 27.3 25.6 34.4 32.3 255.8 58.8 69.9 233.1 9.8 27.7 52.3 91.6 62.3 68.0 54.8 41.8 19.4 40.1 84.9 34.9 39.4 26.8 21.8 42.2 29.7 8.6 18.0 42.9 52.9 23.8 47.5 16.4 47.6 59.1 48.5 56.3 58.7 49.7 21.8 28.1 32.9 33.0 15.3 33.7 145.1 93.2 32.7 88.0 77.4 50.9 55.5 61.8 90.0 45.8 45.8 64.1 63.5 139.3 0.1 116.1 30.1 30.8 16.5 106.4 84.9 81.7 29.7 74.1 119.5 84.1 0.1 53.1 111.5 51.7 70.6 30.4 56.1 76.4 73.1 65.3 17.5 70.5 0.1 94.7 135.0 223.2 38.2 85.6 108.0 93.6 318.2 146.3 24.9 57.7 21.0 32.6 79.0 0.2 87.5 28.4 43.2 56.7 30.7 86.3 15.5 20.9 152.5 47.9 53.4 51.2 33.0 15.3 1.8 28.5 9.4 47.5 28.1 110.7 59.4 28.3 17.7 145.1 92.2 2.5 33.7 6.7 32.9 105.4 93.2 79.5 79.6 52.4 80.1 58.8 69.9 91.6 62.3 84.9 47.6 LDHC CT32 ENSG00000166796 "Lactate dehydrogenase C" P07864 11 18412307-18452058 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "testis: 143.9" "Cell line enhanced" "Detected in some" "U-2197: 8.5;U-266/70: 7.6;U-266/84: 6.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045442 Enhanced "HPA045442: AB_10966720" "unprognostic (2.32e-2)" "unprognostic (3.42e-3)" "unprognostic (1.87e-1)" "unprognostic (2.83e-2)" "unprognostic (2.19e-1)" "unprognostic (8.56e-4)" "unprognostic (1.35e-1)" "unprognostic (5.74e-2)" "unprognostic (6.65e-2)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (1.18e-2)" "unprognostic (1.08e-1)" "unprognostic (9.30e-2)" "unprognostic (3.00e-1)" "unprognostic (4.25e-1)" "unprognostic (1.93e-1)" 0.1 0.1 0.7 0.0 0.9 0.1 0.1 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.1 0.0 0.5 0.2 0.1 0.1 0.4 0.0 0.1 0.3 0.0 0.1 0.4 0.0 0.3 0.0 0.4 0.1 0.0 0.2 0.1 0.0 0.2 0.1 0.3 0.0 0.3 0.0 0.0 143.9 0.3 0.0 0.2 0.1 0.2 0.0 0.0 2.4 2.7 3.6 1.1 0.2 3.8 1.2 0.0 0.0 0.3 1.9 1.4 1.6 1.9 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.1 0.4 0.2 0.0 0.0 0.1 0.2 2.7 0.2 1.0 0.0 0.0 0.2 0.3 0.0 0.4 0.1 0.1 1.0 0.1 0.6 0.0 0.4 0.2 0.5 0.0 0.5 0.1 0.0 0.1 0.0 0.0 1.9 0.0 2.2 3.4 0.5 0.2 0.1 0.8 0.3 2.7 8.5 0.1 7.6 6.7 0.3 0.1 0.0 0.1 1.3 0.7 1.0 0.6 1.0 2.3 0.8 1.8 2.2 0.0 2.4 3.8 2.6 3.6 0.2 1.1 2.7 1.7 1.2 0.7 0.9 0.6 0.4 0.2 0.1 0.3 0.0 0.4 0.3 LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116771 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.3;skeletal muscle: 39.7" "Cell line enhanced" "Detected in many" "Hep G2: 8.5;HMC-1: 11.8;T-47d: 22.9;U-266/70: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 8.9;classical monocyte: 2.7;intermediate monocyte: 4.6;non-classical monocyte: 5.7" "Group enriched" "Detected in many" 31 "granulocytes: 8.9;monocytes: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Cytosol Cytosol "HPA041766: , HPA048639: , HPA066148: " "unprognostic (8.75e-2)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "prognostic favourable (5.61e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-1)" "prognostic favourable (2.95e-14)" "unprognostic (4.10e-3)" "unprognostic (4.49e-2)" "unprognostic (7.00e-2)" "unprognostic (2.20e-1)" 15.3 5.5 6.8 1.6 6.7 0.8 3.7 4.9 11.7 4.1 12.5 7.6 4.5 6.1 1.5 3.0 3.8 2.1 3.6 25.3 6.6 5.8 21.5 44.3 2.8 0.9 8.1 9.7 7.9 7.7 8.5 4.4 2.1 9.9 4.4 6.8 5.1 14.2 4.5 39.7 1.8 2.5 1.2 4.5 0.7 11.2 1.0 4.0 0.0 4.3 14.4 2.7 1.1 1.2 0.0 0.2 8.9 5.7 0.1 0.1 0.9 0.5 1.6 0.0 0.3 1.3 1.1 5.0 0.1 0.1 0.1 0.2 2.1 2.1 0.0 1.7 0.7 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.5 8.5 2.1 0.0 11.8 1.6 0.2 0.0 0.0 0.1 0.6 1.9 0.0 3.9 0.0 0.6 1.1 1.0 0.0 0.0 5.9 1.1 0.1 0.0 0.0 0.0 4.0 0.2 22.9 2.5 0.0 0.0 0.2 0.0 0.0 9.1 0.5 0.0 1.5 0.0 0.0 8.9 2.7 0.8 0.0 4.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 5.7 0.0 0.0 0.9 6.8 6.7 4.9 11.7 6.6 5.8 8.1 9.7 9.9 4.0 LFNG SCDO3 ENSG00000106003 "LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q8NES3 7 2512529-2529177 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 55.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.9;RH-30: 23.5;U-2 OS: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069130 Approved "Intracellular and membrane" 620000 "HPA069130: " "unprognostic (4.58e-2)" "unprognostic (1.17e-2)" "unprognostic (2.52e-2)" "prognostic favourable (6.36e-4)" "unprognostic (1.85e-2)" "unprognostic (8.34e-2)" "unprognostic (4.15e-1)" "unprognostic (7.86e-2)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.89e-1)" "unprognostic (5.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.09e-1)" "unprognostic (1.97e-2)" "unprognostic (2.28e-2)" 10.4 4.9 8.3 12.6 13.5 6.5 15.7 8.3 12.0 10.9 17.3 11.2 0.8 11.9 15.0 5.9 7.9 4.1 16.9 10.1 7.1 11.8 6.6 1.9 15.6 18.1 15.0 6.6 3.0 55.0 1.7 2.6 6.2 19.4 13.0 9.6 8.4 16.5 7.3 3.7 43.0 11.6 6.0 10.2 13.2 28.4 3.4 5.2 5.8 4.4 10.4 19.8 9.0 8.3 2.6 2.5 12.8 7.7 1.3 4.5 1.5 0.7 7.0 9.3 1.3 1.0 0.9 0.6 2.7 1.4 2.4 3.0 3.0 18.9 0.5 8.5 7.3 13.5 1.4 2.5 1.2 4.1 0.3 2.1 3.7 1.5 0.0 3.0 3.9 1.7 6.4 3.9 0.4 0.9 0.3 0.1 1.8 16.8 0.0 4.2 11.3 5.2 0.8 23.5 1.4 0.9 2.2 8.6 2.1 3.1 0.7 0.1 5.1 3.6 2.2 5.4 26.0 0.2 7.4 0.1 0.0 0.7 6.0 8.1 1.0 5.3 5.9 12.8 2.0 7.7 2.4 1.3 2.0 1.0 2.5 2.6 2.2 2.0 3.2 1.3 7.0 0.6 4.5 1.5 8.3 13.5 8.3 12.0 7.1 11.8 15.0 6.6 19.4 5.2 LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748702 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "RPMI-8226: 127.6;U-266/70: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 11 "plasmacytoid DC: 54.2" "Lineage enriched" "Detected in many" 11 "dendritic cells: 54.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" 1200000 Vesicles Nucleoplasm "HPA001426: AB_1079247" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.47e-1)" "prognostic favourable (4.70e-4)" "unprognostic (8.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.18e-3)" "unprognostic (7.24e-2)" 42.9 16.3 8.6 17.4 10.7 3.5 19.9 5.8 17.9 13.3 22.3 11.7 13.9 24.2 12.1 48.1 17.4 14.1 32.7 38.8 10.3 10.1 87.6 44.6 31.5 42.4 8.3 10.1 20.5 14.6 54.4 9.7 113.6 9.9 22.0 24.5 23.2 22.6 8.4 17.3 11.9 37.1 23.3 11.5 58.3 23.7 14.0 7.9 17.2 36.8 19.2 17.3 31.4 18.2 4.7 54.2 0.7 0.8 1.0 4.3 1.7 4.8 7.0 4.7 8.6 14.6 11.8 16.4 10.5 10.0 10.9 12.9 5.4 8.7 2.7 15.5 17.1 12.1 0.0 9.0 5.2 0.2 5.4 0.1 3.9 6.2 4.3 0.1 0.4 8.3 4.4 10.5 6.0 12.9 1.0 22.6 0.7 6.5 1.2 0.2 2.3 4.8 1.2 4.1 127.6 11.8 19.0 5.1 3.5 14.5 8.9 7.5 6.6 0.0 7.0 5.4 6.9 9.7 3.1 70.2 8.2 3.6 3.0 0.1 10.3 0.7 0.4 0.1 0.2 0.8 0.4 4.7 1.4 0.4 5.0 3.4 4.3 2.5 0.5 1.0 0.2 54.2 2.6 1.7 8.6 10.7 5.8 17.9 10.3 10.1 8.3 10.1 9.9 7.9 LHPP HDHD2B ENSG00000107902 "Phospholysine phosphohistidine inorganic pyrophosphate phosphatase" Q9H008 10 124461834-124617888 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 106.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009163, HPA009269" Enhanced Supported "Nuclear speckles,Cytosol" 880000 "Nuclear speckles, Cytosol" "HPA009163: AB_1079250, HPA009269: AB_1079249" "unprognostic (3.46e-2)" "unprognostic (1.23e-2)" "unprognostic (4.78e-2)" "unprognostic (3.89e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-1)" "unprognostic (5.77e-3)" "unprognostic (2.02e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (6.42e-2)" "unprognostic (5.55e-2)" "unprognostic (1.79e-3)" "unprognostic (2.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" 9.6 14.2 37.3 6.0 34.0 6.9 7.9 11.9 34.2 12.3 13.6 29.7 8.2 17.9 7.5 11.0 12.7 8.1 8.3 9.8 43.0 31.5 18.6 33.8 6.6 8.2 62.7 19.3 5.5 12.2 6.6 5.6 7.2 20.5 6.9 6.7 6.7 13.3 10.6 6.5 8.9 15.7 8.1 106.0 8.2 12.4 14.2 19.5 7.1 20.5 3.6 11.2 8.7 5.7 24.7 20.0 13.3 16.1 3.9 17.2 12.9 14.7 7.3 3.0 7.5 11.6 9.5 7.9 5.4 11.1 3.4 6.3 1.3 13.7 14.6 12.6 8.1 16.0 0.9 2.8 3.6 3.2 10.5 10.6 2.3 6.7 11.8 2.1 17.3 7.0 12.5 3.4 8.2 5.4 5.2 5.8 4.2 14.6 7.0 6.8 5.3 4.1 7.5 3.3 18.6 7.4 1.9 1.6 9.0 3.8 13.9 4.9 10.5 0.3 2.5 5.3 7.9 4.4 1.4 4.9 1.5 4.7 4.9 4.1 1.2 4.6 16.1 13.3 9.5 13.5 12.4 23.7 11.1 10.1 20.0 24.7 13.7 9.6 2.7 3.9 14.9 7.5 17.2 12.9 37.3 34.0 11.9 25.0 43.0 31.5 62.7 19.3 20.5 19.5 LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39458587-39485109 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria,Cytosol Mitochondria "Nucleoplasm, Cytosol" "HPA018842: AB_1852864, HPA019076: AB_1852866" "unprognostic (3.61e-1)" "unprognostic (1.89e-1)" "unprognostic (8.44e-2)" "unprognostic (2.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (4.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.46e-3)" "unprognostic (3.80e-2)" "prognostic favourable (4.11e-7)" "unprognostic (9.41e-3)" "unprognostic (2.35e-1)" "unprognostic (5.45e-2)" "unprognostic (6.98e-2)" 9.8 12.9 9.9 7.0 12.7 10.2 11.3 10.2 13.3 7.0 10.7 12.9 8.1 10.4 9.1 10.7 11.6 11.9 7.4 14.0 10.6 10.6 15.7 15.5 5.7 9.0 12.3 10.5 19.2 12.4 10.0 11.5 6.8 15.7 8.2 12.4 9.0 7.8 7.0 42.7 8.8 9.9 13.6 12.4 8.9 9.9 20.1 13.2 8.7 8.8 13.5 8.3 10.0 7.9 9.6 5.8 3.7 7.1 6.9 16.7 4.3 3.9 3.0 4.0 3.7 8.3 8.1 3.4 4.6 2.5 4.3 2.9 5.0 5.5 14.4 5.3 1.7 3.5 11.1 6.3 5.7 1.6 2.8 6.0 1.6 5.0 7.6 13.1 3.9 7.8 10.4 5.0 16.0 4.9 14.3 3.6 5.2 2.5 7.3 16.8 5.2 10.0 6.4 10.7 8.7 5.1 2.1 4.3 3.7 2.6 3.5 14.8 3.9 6.0 1.8 3.4 7.6 4.5 10.6 7.0 10.6 10.1 5.3 15.3 2.9 2.0 6.2 3.7 6.1 7.1 12.6 9.6 8.3 8.0 5.8 8.5 16.7 11.5 3.3 6.9 5.1 5.4 5.2 4.3 9.9 12.7 10.2 13.3 10.6 10.6 12.3 10.5 15.7 13.2 LIG1 ENSG00000105486 "DNA ligase 1" P18858 19 48115445-48170603 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037015, HPA041431, HPA048071" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Nucleoplasm "Golgi apparatus, Vesicles" "CAB037015: , HPA041431: , HPA048071: " "unprognostic (1.83e-1)" "unprognostic (1.48e-3)" "unprognostic (6.45e-2)" "unprognostic (9.76e-2)" "unprognostic (9.47e-2)" "unprognostic (9.24e-3)" "unprognostic (1.17e-3)" "unprognostic (2.28e-1)" "unprognostic (6.03e-3)" "unprognostic (4.26e-1)" "unprognostic (1.78e-2)" "unprognostic (1.10e-3)" "prognostic unfavourable (5.75e-5)" "unprognostic (3.59e-2)" "unprognostic (4.09e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" 4.1 5.6 8.1 25.2 10.4 37.8 6.4 17.2 10.6 6.5 9.2 6.5 8.7 12.0 6.8 6.1 11.0 7.8 6.9 2.6 6.3 5.3 6.0 6.2 5.9 18.6 7.7 7.4 10.8 10.3 9.1 9.7 11.7 8.1 7.5 6.0 4.6 7.2 7.9 6.1 12.5 12.8 3.6 7.1 11.2 6.7 15.1 11.5 34.7 10.7 12.1 16.9 6.6 8.6 10.4 1.3 2.0 5.6 10.9 11.5 4.8 15.7 20.3 21.7 14.0 0.9 1.1 15.7 9.1 6.8 14.8 16.3 11.5 15.5 28.5 5.6 3.8 10.6 8.9 9.0 6.4 15.4 15.4 17.6 14.3 14.8 0.3 21.8 14.6 2.0 0.7 7.9 1.2 7.9 14.9 10.7 7.4 12.6 34.9 32.5 12.3 4.7 30.1 17.0 14.1 4.5 24.1 13.8 13.7 11.0 12.9 3.1 8.3 16.8 7.7 11.8 19.9 9.9 14.2 10.6 16.7 29.0 4.8 12.3 13.0 0.0 1.4 2.0 7.6 5.6 6.8 10.3 8.4 7.6 1.3 10.4 11.5 8.0 1.1 10.9 2.7 1.2 8.9 4.8 8.1 10.4 17.2 10.6 6.3 5.3 7.7 7.4 8.1 11.5 LIG3 LIG2 ENSG00000005156 "DNA ligase 3" P49916 17 34980494-35009743 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006723 Supported Supported Nucleoplasm Nucleoplasm "HPA006723: AB_1847781" "unprognostic (6.05e-3)" "unprognostic (2.98e-1)" "unprognostic (1.24e-1)" "unprognostic (2.83e-1)" "unprognostic (1.57e-1)" "unprognostic (8.76e-2)" "unprognostic (2.40e-2)" "unprognostic (2.78e-1)" "unprognostic (2.25e-1)" "unprognostic (1.02e-2)" "unprognostic (8.77e-3)" "unprognostic (1.31e-1)" "unprognostic (6.67e-3)" "unprognostic (3.39e-1)" "unprognostic (3.28e-1)" "unprognostic (3.29e-2)" "unprognostic (4.71e-2)" 8.8 11.5 10.7 9.8 17.0 9.2 12.5 15.9 18.3 14.7 11.5 15.8 11.4 8.4 21.5 12.3 14.2 17.3 7.9 11.0 14.2 8.0 9.8 11.8 9.8 9.6 9.1 11.7 17.8 15.4 22.9 13.3 16.5 9.3 16.5 13.1 11.8 14.3 13.9 17.0 13.9 9.8 14.7 8.0 14.3 11.6 27.8 10.9 20.8 14.5 9.7 13.9 13.6 12.7 4.6 10.1 4.8 6.3 11.1 8.4 4.5 8.1 16.3 19.7 17.3 3.9 4.9 15.1 7.9 5.8 10.8 10.8 7.9 4.5 13.4 6.6 10.3 7.6 22.3 10.2 13.9 6.3 14.9 14.0 7.8 11.4 6.2 21.9 24.9 3.7 9.0 7.9 12.5 13.0 22.0 15.4 7.8 9.1 27.5 7.0 18.9 6.9 15.0 18.1 14.1 5.3 8.9 16.1 11.5 11.9 9.7 7.7 17.6 11.0 6.2 7.0 8.8 8.6 12.7 13.9 14.9 17.4 5.0 10.4 13.4 0.6 3.8 4.8 5.9 6.3 8.4 4.6 4.0 5.2 10.1 4.0 5.4 3.8 0.3 11.1 3.2 6.0 2.5 4.5 10.7 17.0 15.9 18.3 14.2 8.0 9.1 11.7 9.3 10.9 LIG4 ENSG00000174405 "DNA ligase 4" P49917 13 108207439-108218368 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Cancer-related genes, Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001334, HPA057325" Supported Supported "Nucleoplasm,Cytoplasmic bodies" Nucleoplasm "Cytoplasmic bodies" "HPA001334: AB_1078689, HPA057325: " "unprognostic (9.93e-2)" "unprognostic (1.56e-1)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (1.40e-1)" "unprognostic (1.97e-1)" "unprognostic (1.56e-1)" "unprognostic (7.97e-2)" "unprognostic (2.43e-1)" "unprognostic (4.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.21e-3)" "unprognostic (1.94e-2)" "unprognostic (3.04e-1)" "unprognostic (1.82e-1)" "unprognostic (1.50e-2)" "unprognostic (9.03e-3)" 8.8 12.4 11.6 10.4 15.9 4.3 9.1 14.2 20.6 5.4 7.1 10.2 7.8 8.9 5.8 11.4 8.1 5.9 8.7 8.8 15.6 14.4 11.2 16.7 8.7 12.7 15.5 10.6 7.9 8.3 17.0 20.3 8.3 19.6 7.5 8.7 3.8 6.7 7.1 9.5 6.6 8.6 8.4 14.4 12.6 9.7 11.7 13.6 18.6 10.0 5.4 10.2 8.1 5.3 3.3 2.1 6.8 10.7 2.7 2.7 1.5 9.4 3.6 9.8 6.5 8.2 8.8 3.5 9.4 7.1 7.2 8.7 4.3 4.3 16.2 7.7 6.1 3.9 6.5 6.3 12.5 9.4 6.2 7.6 8.3 2.2 9.8 10.2 8.1 8.0 10.5 7.0 6.3 8.6 2.7 3.0 11.1 5.1 16.8 7.4 2.5 2.3 15.5 3.9 2.6 9.4 6.1 6.2 6.4 2.1 5.8 7.1 4.9 15.7 12.7 4.3 4.7 4.8 8.4 8.0 5.2 26.3 16.6 5.9 9.7 0.8 2.3 6.8 1.8 3.8 2.5 2.6 2.0 1.9 2.1 3.3 2.0 2.7 3.2 2.7 10.7 1.4 2.7 1.5 11.6 15.9 14.2 20.6 15.6 14.4 15.5 10.6 19.6 13.6 LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.2" "Cell line enhanced" "Detected in all" "U-87 MG: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028064, HPA028516" Approved Supported "Nuclear speckles,Cytosol" "Nuclear speckles, Cytosol" "HPA028064: AB_10600111, HPA028516: AB_10601751" "unprognostic (1.45e-2)" "unprognostic (2.75e-1)" "prognostic unfavourable (4.95e-5)" "unprognostic (2.77e-2)" "unprognostic (1.40e-3)" "unprognostic (3.35e-2)" "prognostic unfavourable (7.79e-6)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" "unprognostic (3.16e-2)" "prognostic unfavourable (6.63e-8)" "unprognostic (4.14e-2)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (5.79e-2)" 8.8 8.6 31.6 18.2 18.6 6.3 7.4 14.3 44.1 11.5 6.6 7.1 6.6 6.9 7.3 5.3 6.4 6.0 10.8 6.3 26.8 32.9 5.2 2.6 12.5 22.0 33.4 22.2 12.1 8.1 4.0 7.2 8.0 45.2 6.1 4.7 4.8 18.1 9.6 10.9 6.8 7.2 7.6 10.8 18.4 7.8 10.4 6.5 4.3 7.5 3.7 18.1 14.1 7.2 4.6 8.6 3.8 7.7 6.9 2.4 3.1 17.2 13.5 10.3 17.1 13.6 18.5 7.5 10.7 10.3 8.7 9.7 7.8 17.0 10.7 4.8 13.1 10.4 3.8 6.6 3.3 18.5 6.7 7.9 4.6 8.9 15.6 6.0 29.0 18.2 5.9 7.0 3.7 12.9 5.3 3.4 10.8 15.1 5.1 10.8 19.5 8.4 7.5 16.0 6.7 9.6 3.7 4.1 9.4 6.9 16.5 8.6 5.2 5.4 15.3 13.9 12.9 35.7 17.1 3.9 4.3 19.5 51.4 4.4 9.4 0.1 6.5 3.8 2.4 7.7 1.8 4.6 0.6 1.5 8.6 2.4 0.2 0.7 0.7 6.9 4.7 0.8 0.4 3.1 31.6 18.6 14.3 44.1 26.8 32.9 33.4 22.2 45.2 6.5 LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 37.8;hTCEpi: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 14.7;neutrophil: 37.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB019313: , HPA008183: AB_1079252, HPA053882: " "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavourable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" 9.4 6.6 23.5 23.6 26.2 29.4 17.0 9.9 16.8 11.0 20.9 15.6 10.7 13.1 12.9 8.7 33.7 22.1 28.7 6.0 15.4 10.7 15.4 19.9 21.6 18.1 20.8 7.2 11.4 19.9 20.0 12.8 64.3 23.3 17.1 22.1 10.1 25.7 16.2 9.7 36.7 13.3 10.1 28.3 17.4 18.5 16.8 17.9 12.4 25.8 15.6 15.3 13.1 20.0 1.0 1.6 37.2 1.9 2.4 5.6 1.6 7.0 1.1 4.9 2.7 2.1 2.5 37.8 4.7 2.2 4.7 4.0 6.1 3.3 6.9 8.4 7.0 14.4 5.7 24.6 3.0 5.0 6.2 5.0 5.6 6.5 3.2 9.2 9.2 4.0 70.1 3.8 11.5 12.0 2.8 5.0 6.4 5.5 5.6 3.2 4.6 1.8 7.5 8.3 3.8 5.5 16.8 6.3 5.7 3.5 22.7 9.4 18.9 3.7 7.2 4.2 6.6 2.3 4.3 2.8 4.1 6.0 2.7 4.4 1.8 2.1 1.9 14.7 1.3 1.3 2.4 0.8 2.3 1.7 0.7 1.0 2.3 1.8 37.2 2.4 0.5 1.6 5.6 1.6 23.5 26.2 9.9 16.8 15.4 10.7 20.8 7.2 23.3 17.9 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 139.0" "Cell line enhanced" "Detected in many" "AN3-CA: 60.3;ASC TERT1: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 31.8;intermediate monocyte: 68.4;myeloid DC: 23.3;non-classical monocyte: 35.6" "Group enriched" "Detected in all" 5 "dendritic cells: 23.3;monocytes: 68.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported Vesicles "Intracellular and membrane" 150000 Vesicles "CAB034892: AB_784329, HPA057052: " "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 139.0 16.3 15.8 14.4 22.7 7.8 19.9 8.8 21.4 13.4 28.1 61.3 3.4 37.4 10.2 5.2 9.5 9.0 19.4 8.7 22.5 13.8 10.8 49.3 38.5 45.7 41.6 13.4 10.4 9.5 17.5 6.3 17.8 28.4 7.4 16.7 5.7 11.0 8.8 4.1 6.8 65.8 11.3 55.1 87.3 7.9 3.1 37.2 7.0 8.3 4.7 10.0 15.1 8.6 7.0 23.3 3.2 68.4 5.5 8.3 25.5 53.8 8.3 5.5 60.3 56.9 75.6 1.6 28.6 33.5 11.9 21.5 3.2 29.1 9.9 5.6 44.8 54.1 2.4 15.5 8.9 14.0 5.6 4.1 3.5 12.8 15.0 8.0 8.2 33.6 11.1 12.7 6.9 2.3 0.0 18.6 9.3 4.5 6.9 5.4 3.6 9.4 4.5 6.5 9.2 11.0 8.5 1.8 3.8 6.9 9.0 21.0 10.3 10.3 4.3 10.2 2.7 21.8 6.9 9.7 10.2 4.1 12.2 17.6 12.7 0.8 31.8 3.2 8.2 68.4 8.2 6.5 7.3 7.8 23.3 7.0 7.7 8.3 1.4 5.5 35.6 4.7 7.1 25.5 15.8 22.7 8.8 21.4 22.5 13.8 41.6 13.4 28.4 37.2 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401507-42427426 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 207.4;breast: 65.1" "Cell line enriched" "Detected in many" 7 "ASC diff: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol Cytosol "CAB017700: AB_2135504, HPA006567: " "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favourable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 207.4 6.0 3.2 2.9 9.4 2.1 65.1 2.0 6.8 1.2 6.7 19.6 0.8 2.4 1.7 1.3 2.2 1.6 3.6 4.8 6.2 4.2 1.5 1.1 1.4 2.7 18.0 2.3 1.5 2.2 2.2 0.8 1.7 9.9 1.7 1.3 3.7 5.4 1.7 3.7 2.9 3.4 1.7 19.2 3.1 1.6 9.0 10.8 1.7 1.5 1.8 1.9 2.0 3.7 6.1 4.8 10.8 12.1 4.1 5.2 4.0 4.8 3.7 2.4 0.9 56.0 0.5 0.0 2.3 1.2 3.7 3.4 0.9 1.8 8.0 2.5 0.7 2.1 1.4 4.5 0.4 1.5 2.4 2.2 1.8 0.1 1.1 0.0 5.5 0.4 4.3 0.6 0.8 1.0 1.0 5.1 0.4 0.0 5.6 0.2 0.3 1.1 4.6 0.4 2.6 1.0 5.1 3.4 3.5 2.0 2.3 2.1 0.6 2.9 1.8 1.0 3.2 0.4 2.0 3.8 3.1 5.9 2.5 0.2 3.4 10.8 12.1 4.7 3.6 6.0 3.3 4.8 4.6 5.2 4.8 6.1 4.1 3.7 2.0 4.1 3.3 3.9 3.9 4.0 3.2 9.4 2.0 6.8 6.2 4.2 18.0 2.3 9.9 10.8 LIPF "HGL, HLAL" ENSG00000182333 "Lipase F, gastric type" P07098 10 88664441-88678814 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "stomach 1: 762.9" "Cell line enhanced" "Detected in some" "HMC-1: 6.2;MOLT-4: 4.9;NTERA-2: 5.2;REH: 3.0;THP-1: 9.8;U-2 OS: 3.5;U-266/70: 4.8" "Cancer enriched" "Detected in some" 75 "stomach cancer: 278.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.9" "Cell type enriched" "Detected in single" 16 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.5" "Region enriched" "Detected in single" 51 "olfactory region: 9.9" HPA045930 Enhanced "Secreted to digestive system" "HPA045930: AB_10959518" "unprognostic (1.53e-1)" "unprognostic (1.83e-1)" 0.1 0.0 0.1 0.1 0.5 0.0 0.1 0.1 1.9 0.1 0.2 28.2 0.1 8.2 0.1 0.1 31.6 0.1 0.6 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.1 9.9 0.1 0.1 0.0 0.1 0.1 0.1 0.1 762.9 0.1 0.1 0.2 0.1 1.1 0.1 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.1 5.2 0.0 3.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 3.5 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 1.9 0.1 0.0 0.1 0.1 0.1 0.1 LIPG EDL ENSG00000101670 "Lipase G, endothelial type" Q9Y5X9 18 49560699-49599182 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 37.0;placenta: 44.7;thyroid gland: 84.3" "Cell line enhanced" "Detected in some" "AN3-CA: 30.7;HaCaT: 47.1;RPTEC TERT1: 31.3;TIME: 61.1" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 20.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 3.7;basal ganglia: 2.1;cerebral cortex: 2.9;hippocampal formation: 1.8;olfactory region: 1.9" "Low region specificity" "Detected in all" HPA016966 Uncertain "Secreted to blood" 656750000 170000 "HPA016966: AB_1852893" "unprognostic (2.20e-2)" "unprognostic (3.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.25e-3)" "unprognostic (6.38e-2)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" "unprognostic (4.55e-3)" "unprognostic (9.93e-2)" "unprognostic (1.44e-1)" "unprognostic (6.44e-2)" "unprognostic (8.74e-2)" "unprognostic (2.98e-1)" "unprognostic (8.68e-2)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (1.35e-1)" 1.5 0.4 0.8 4.7 0.7 0.1 0.8 2.0 0.7 0.4 5.6 3.9 15.0 1.9 0.4 3.1 1.0 0.5 4.3 1.2 1.1 0.9 5.2 37.0 4.4 0.7 1.1 0.1 0.5 1.0 0.0 0.6 44.7 1.4 1.0 2.2 8.3 0.6 24.6 2.6 1.1 7.6 2.2 1.4 0.4 1.4 5.8 0.4 0.3 84.3 2.1 0.5 2.0 0.6 1.2 0.6 2.1 0.6 1.7 0.8 0.1 0.5 0.0 13.5 30.7 0.1 0.0 0.2 0.1 1.4 0.0 0.0 13.3 4.8 0.0 7.5 0.0 47.1 2.0 9.6 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.2 1.4 10.8 4.8 9.4 7.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.7 31.3 3.6 0.2 0.0 0.2 0.3 0.0 0.0 0.0 61.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.6 0.4 0.7 0.4 0.4 0.8 0.5 0.5 0.2 1.2 0.8 0.7 2.1 1.7 0.4 0.6 0.4 0.1 0.8 0.7 2.0 0.5 1.1 0.9 1.1 0.1 1.4 0.4 LIPT2 ENSG00000175536 "Lipoyl(octanoyl) transferase 2" A6NK58 11 74491712-74493733 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Ligase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040249 Approved Approved Vesicles,Centrosome Vesicles Centrosome "HPA040249: AB_10795275" "unprognostic (8.80e-2)" "unprognostic (9.67e-2)" "unprognostic (5.12e-3)" "unprognostic (1.09e-1)" "unprognostic (6.74e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-2)" "unprognostic (8.96e-2)" "unprognostic (1.11e-2)" "prognostic favourable (1.63e-4)" "unprognostic (6.11e-2)" "unprognostic (2.02e-1)" "unprognostic (1.17e-2)" "unprognostic (9.45e-2)" "unprognostic (1.01e-1)" "unprognostic (1.51e-2)" "unprognostic (1.35e-1)" 2.0 4.1 2.6 2.6 3.0 2.1 5.8 2.3 4.3 3.1 4.0 3.4 6.5 5.8 3.4 6.5 3.6 5.8 8.8 2.9 3.3 2.6 8.1 5.3 4.0 8.4 3.5 1.0 6.2 10.8 6.2 4.3 8.3 2.9 4.6 3.6 3.8 5.9 6.9 11.3 2.4 6.3 3.1 2.9 4.2 5.6 19.0 0.8 8.7 6.4 5.5 4.3 4.6 3.8 11.2 7.2 6.6 4.9 8.1 14.8 5.4 2.5 3.2 7.0 3.3 2.9 0.6 9.9 0.9 1.6 4.4 2.8 10.5 3.5 15.5 6.0 0.6 3.7 3.2 2.4 1.7 3.6 3.2 4.5 2.8 2.8 3.3 5.2 6.2 1.6 2.6 2.2 2.9 0.3 3.5 4.4 1.3 4.0 6.9 7.9 6.2 4.2 5.6 7.7 4.3 2.9 8.7 7.1 4.5 6.5 2.0 9.4 6.3 3.9 1.2 1.0 2.6 1.5 2.3 7.3 6.5 10.5 0.8 3.0 3.4 0.0 4.9 6.6 5.9 3.0 8.8 11.2 7.9 7.2 5.3 11.0 14.8 11.2 1.1 8.1 3.7 7.2 3.7 5.4 2.6 3.0 2.3 4.3 3.3 2.6 3.5 1.0 2.9 0.8 LMLN "Gp63, LMNL1, Msp" ENSG00000185621 "Leishmanolysin like peptidase" Q96KR4 3 197960200-198043720 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016481, HPA028844" Uncertain Supported "Focal adhesion sites,Cytosol" Cytosol "Focal adhesion sites" "HPA016481: AB_1852955, HPA028844: AB_10602347" "unprognostic (2.54e-1)" "unprognostic (3.15e-1)" "unprognostic (7.63e-2)" "prognostic favourable (6.77e-4)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (1.94e-1)" "unprognostic (2.31e-1)" "unprognostic (6.36e-2)" "unprognostic (2.98e-1)" "unprognostic (4.82e-3)" "unprognostic (8.78e-2)" "unprognostic (7.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.63e-1)" 3.9 4.9 5.2 2.5 11.0 2.3 4.5 6.1 9.1 6.2 3.5 5.8 14.3 2.2 4.8 20.3 3.5 9.3 5.1 5.9 5.7 7.4 6.6 3.7 8.1 3.5 5.6 8.9 6.5 6.1 8.8 15.0 3.9 11.6 4.6 4.1 5.4 4.2 11.7 3.7 6.5 2.3 4.0 5.5 3.0 3.9 27.0 4.4 1.2 7.6 3.0 2.6 3.5 3.7 1.9 1.9 0.8 2.4 1.8 2.4 1.2 6.5 2.5 3.0 3.5 5.9 8.3 2.5 3.4 3.1 6.2 5.1 2.4 2.4 2.1 16.0 2.4 2.5 2.8 2.7 9.0 0.3 2.0 1.2 2.1 1.8 3.7 3.7 1.8 3.9 6.1 7.7 5.0 2.7 6.3 4.0 5.9 4.9 2.2 3.2 3.3 6.0 2.5 0.7 2.2 6.4 1.7 4.8 1.4 4.8 4.3 3.4 11.1 2.8 5.7 7.6 1.1 9.2 5.7 7.1 13.8 0.6 10.9 6.4 6.9 0.2 0.6 0.5 1.2 2.4 1.7 1.9 0.8 1.6 1.9 1.1 2.2 2.4 0.8 1.8 0.9 0.5 0.0 1.2 5.2 11.0 6.1 9.1 5.7 7.4 5.6 8.9 11.6 4.4 LMTK2 "AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100" ENSG00000164715 "Lemur tyrosine kinase 2" Q8IWU2 7 98106885-98209633 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 4.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010657, HPA041836" Uncertain Approved "Nuclear speckles,Plasma membrane,Centriolar satellite,Cytosol" "Nuclear speckles, Centriolar satellite" "Plasma membrane, Cytosol" "HPA010657: AB_1079259, HPA041836: " "unprognostic (7.36e-2)" "unprognostic (3.16e-1)" "unprognostic (1.59e-1)" "unprognostic (2.60e-3)" "unprognostic (2.47e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-2)" "unprognostic (1.23e-1)" "unprognostic (4.96e-1)" "prognostic unfavourable (8.03e-4)" "unprognostic (1.23e-1)" "unprognostic (4.65e-1)" "prognostic favourable (1.12e-7)" "unprognostic (1.88e-1)" "unprognostic (3.92e-1)" "unprognostic (2.16e-2)" "unprognostic (6.38e-3)" 5.1 10.3 13.7 5.6 21.3 17.3 5.6 16.6 34.3 7.3 13.8 6.1 5.6 12.6 6.1 6.3 12.7 6.4 7.9 16.9 11.0 10.1 10.1 8.5 10.0 5.1 7.5 18.9 8.0 21.0 22.2 10.0 4.8 13.2 7.9 11.8 5.4 10.5 6.5 17.5 11.5 13.8 5.7 5.5 6.8 9.4 8.0 6.9 7.2 8.7 5.7 7.4 8.3 8.1 0.6 0.7 4.8 0.9 0.3 1.6 0.5 9.9 11.7 9.1 9.3 4.9 3.9 8.5 4.1 4.5 4.1 4.9 9.2 9.1 5.2 11.9 5.3 10.9 10.5 6.3 6.4 7.4 7.4 3.5 10.5 9.2 6.0 6.3 6.4 2.7 8.8 8.4 11.4 6.1 9.2 11.1 3.7 13.5 6.6 3.8 11.1 5.7 7.3 6.2 10.3 6.8 17.5 6.5 13.1 8.3 15.2 6.0 4.2 2.6 7.4 8.5 14.0 16.9 9.4 4.9 8.6 10.5 5.7 5.0 10.1 1.2 0.6 0.5 0.8 0.3 0.5 0.6 0.9 0.9 0.3 0.6 1.1 1.6 4.8 0.3 0.9 0.7 0.8 0.5 13.7 21.3 16.6 34.3 11.0 10.1 7.5 18.9 13.2 6.9 LMTK3 "KIAA1883, LMR3, PPP1R101, TYKLM3" ENSG00000142235 "Lemur tyrosine kinase 3" Q96Q04 19 48485271-48513189 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 38.1" "Cell line enhanced" "Detected in many" "HMC-1: 8.4;SK-BR-3: 10.0;U-266/70: 9.3;U-266/84: 7.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040203, HPA077070" Enhanced Approved "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "HPA040203: AB_10671690, HPA077070: " "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (5.37e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-1)" "unprognostic (1.71e-2)" "unprognostic (5.67e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-3)" "unprognostic (5.71e-2)" "unprognostic (1.47e-1)" "prognostic favourable (3.18e-8)" "unprognostic (1.38e-1)" "unprognostic (3.22e-2)" "unprognostic (3.24e-1)" "unprognostic (6.11e-2)" 1.3 4.4 19.8 2.3 28.6 2.0 2.0 20.0 38.1 2.0 1.5 6.0 0.2 6.2 1.4 1.5 2.3 1.6 1.9 1.7 17.2 11.1 2.5 1.3 3.2 2.2 6.5 23.8 1.3 2.1 8.5 6.1 2.1 12.5 3.5 1.2 1.6 5.2 3.1 1.2 2.4 4.0 1.2 6.6 1.8 2.9 1.5 10.3 0.0 2.3 0.0 2.2 1.6 1.2 0.0 0.0 0.0 0.2 0.0 0.4 0.1 4.5 3.0 0.3 0.0 0.0 0.0 4.4 0.0 0.2 0.0 0.1 2.2 3.6 1.6 1.2 0.0 2.1 0.3 1.6 0.0 0.0 1.2 0.2 0.3 0.7 0.0 0.0 8.4 0.2 0.9 0.0 0.0 0.1 1.4 2.8 0.0 3.0 0.6 0.8 1.1 0.9 3.8 0.0 1.3 1.1 0.7 0.7 2.8 0.1 10.0 0.0 3.8 0.2 0.1 0.0 0.8 0.1 0.0 9.3 7.5 0.4 0.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 19.8 28.6 20.0 38.1 17.2 11.1 6.5 23.8 12.5 10.3 LNPEP "CAP, IRAP, P-LAP, PLAP" ENSG00000113441 "Leucyl and cystinyl aminopeptidase" Q9UIQ6 5 96935394-97037515 "Enzymes, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "placenta: 104.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043642 Approved "Intracellular and membrane" 390000 "HPA043642: AB_10964137" "unprognostic (1.52e-1)" "unprognostic (5.39e-2)" "unprognostic (7.78e-2)" "unprognostic (1.53e-2)" "unprognostic (6.38e-2)" "unprognostic (6.59e-3)" "unprognostic (6.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.11e-1)" "unprognostic (3.54e-3)" "unprognostic (6.24e-2)" "unprognostic (2.08e-1)" "unprognostic (3.28e-1)" "unprognostic (4.13e-3)" "unprognostic (1.46e-1)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" 9.8 4.7 5.6 12.0 7.3 13.2 7.7 23.3 12.9 6.3 7.6 6.9 7.8 4.2 8.2 4.4 10.2 6.6 4.3 10.1 5.2 5.6 7.6 4.3 6.9 15.9 7.7 8.8 8.2 5.9 13.8 9.7 104.4 9.1 7.9 6.8 3.9 7.8 7.7 13.2 14.0 9.0 6.6 7.5 10.0 8.5 3.3 7.7 23.6 7.2 2.9 15.8 8.9 7.7 4.1 3.5 5.0 12.8 11.2 7.9 4.3 5.3 6.2 2.8 3.0 17.1 8.2 3.3 5.5 7.3 6.5 9.9 5.2 8.7 26.5 10.4 7.4 7.1 3.6 10.4 6.8 9.4 2.0 6.6 4.5 3.6 4.4 7.6 9.2 6.3 6.5 9.4 6.9 6.8 2.8 17.6 7.4 4.8 9.0 5.3 0.6 3.3 6.6 10.6 4.0 23.2 11.1 5.5 1.4 6.7 5.9 3.3 18.1 10.1 13.5 9.5 5.3 7.5 8.3 3.8 8.8 24.2 8.4 7.3 4.3 5.0 3.3 4.4 7.9 5.5 6.8 3.1 5.9 6.1 3.5 4.1 5.9 6.4 4.1 11.2 12.8 3.3 5.1 4.3 5.6 7.3 23.3 12.9 5.2 5.6 7.7 8.8 9.1 7.7 LNX1 "LNX, MPDZ, PDZRN2" ENSG00000072201 "Ligand of numb-protein X 1" Q8TBB1 4 53459301-53701405 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002235, HPA071091" Approved Supported "Cell Junctions,Cytosol" "Intracellular and membrane" "Cell Junctions" Cytosol "HPA002235: AB_1079261, HPA071091: " "unprognostic (4.95e-2)" "unprognostic (1.74e-2)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (2.79e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (5.62e-2)" "unprognostic (8.14e-2)" "unprognostic (1.06e-1)" "unprognostic (5.18e-2)" "unprognostic (8.56e-2)" "prognostic favourable (3.08e-7)" "unprognostic (2.67e-1)" "unprognostic (5.49e-2)" "unprognostic (6.81e-2)" "unprognostic (3.05e-2)" 16.9 2.5 11.8 1.7 24.6 0.8 13.2 4.4 33.3 5.9 7.2 1.5 11.2 8.3 4.5 3.2 21.7 5.6 4.8 6.9 6.1 5.5 10.0 3.7 2.5 1.8 3.8 11.6 2.1 12.9 10.8 5.0 21.6 4.8 5.1 5.6 2.0 22.1 10.0 5.1 10.0 8.2 2.8 1.3 0.9 8.0 4.1 2.0 0.7 15.0 5.7 7.8 5.8 7.7 1.4 1.1 1.5 1.9 3.8 1.6 0.6 1.6 0.6 1.9 1.0 3.5 7.3 9.2 1.5 0.7 0.0 0.0 2.7 8.4 2.1 1.2 4.2 1.6 0.0 0.3 0.0 0.5 4.6 2.9 1.7 1.6 1.4 2.7 0.8 5.4 0.3 0.5 0.0 2.8 1.7 1.0 6.6 4.7 2.4 1.8 4.8 1.0 1.5 0.7 0.9 6.3 8.8 2.3 2.6 0.7 9.7 1.0 5.2 1.4 8.0 10.5 3.1 3.4 1.8 3.9 0.6 1.4 9.6 2.4 1.9 1.5 0.5 0.3 1.0 0.5 1.5 1.4 1.5 1.5 0.8 0.9 1.6 1.2 0.4 3.8 1.9 1.1 1.3 0.6 11.8 24.6 4.4 33.3 6.1 5.5 3.8 11.6 4.8 2.0 LONP1 "hLON, LonHS, PIM1, PRSS15" ENSG00000196365 "Lon peptidase 1, mitochondrial" P36776 19 5691834-5720572 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Hydrolase, Protease, Serine protease" "Cataract, Deafness, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 78.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002034, HPA002192" Supported Enhanced Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA002034: AB_2756304, HPA002192: AB_1079695" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (2.43e-1)" "unprognostic (2.43e-2)" "unprognostic (2.84e-1)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (5.56e-2)" "unprognostic (2.71e-1)" "unprognostic (7.57e-2)" "unprognostic (4.04e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" 15.8 78.3 16.4 12.8 19.8 12.5 13.9 16.1 22.8 11.3 13.6 15.8 13.3 13.7 10.5 13.8 12.7 12.7 15.7 27.3 15.4 15.3 19.9 49.6 10.3 14.5 17.7 14.9 15.5 17.7 17.6 16.8 16.6 16.2 11.7 8.5 12.7 18.5 14.7 38.0 14.7 13.9 11.5 12.7 15.5 13.5 9.8 13.3 13.8 21.2 15.3 11.8 14.7 12.5 6.7 6.5 6.0 6.2 4.0 7.2 3.0 23.0 23.9 7.9 25.3 9.4 6.7 24.7 14.7 11.7 15.9 19.5 20.4 8.3 29.0 20.6 15.4 9.8 20.4 17.8 7.7 17.1 16.8 16.0 20.9 26.7 43.7 36.4 16.8 12.6 25.6 15.1 29.9 12.7 42.3 57.8 7.3 15.3 18.0 21.7 28.3 31.6 19.0 11.4 31.2 8.8 13.7 21.1 21.1 12.9 18.9 51.6 11.1 45.7 9.0 8.1 8.9 22.5 21.4 60.9 37.5 25.7 36.5 39.9 14.6 6.0 4.1 0.8 6.4 6.2 4.1 6.0 5.6 6.1 4.3 6.7 7.2 4.8 0.5 4.0 2.4 6.5 4.0 3.0 16.4 19.8 16.1 22.8 15.4 15.3 17.7 14.9 16.2 13.3 LONP2 "LONP, LONPL, MGC4840" ENSG00000102910 "Lon peptidase 2, peroxisomal" Q86WA8 16 48244296-48363122 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008862 Uncertain "HPA008862: AB_2137156" "unprognostic (8.08e-3)" "prognostic unfavourable (4.55e-4)" "unprognostic (1.75e-2)" "unprognostic (2.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.60e-2)" "unprognostic (7.59e-3)" "unprognostic (2.13e-1)" "unprognostic (2.36e-1)" "unprognostic (3.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.40e-1)" "prognostic favourable (6.71e-7)" "unprognostic (6.53e-2)" "unprognostic (1.49e-1)" "unprognostic (5.60e-2)" "unprognostic (1.33e-1)" 15.8 17.0 16.0 13.9 22.2 9.4 36.1 18.9 20.7 16.1 17.4 16.3 15.3 15.2 15.8 20.6 14.5 17.6 19.0 16.7 15.0 15.0 15.9 69.2 11.3 12.8 15.2 15.8 22.1 20.7 40.0 23.3 11.1 17.2 23.1 14.8 30.9 15.0 18.1 18.0 13.5 14.8 16.3 14.1 12.5 14.9 7.0 13.7 14.9 24.9 11.6 13.2 16.7 13.7 13.3 13.1 8.7 13.7 9.0 15.9 11.0 13.7 19.3 9.7 14.9 25.7 21.2 18.4 17.8 13.6 16.7 7.7 10.0 7.1 6.3 17.6 17.8 17.3 19.7 19.6 23.4 10.2 12.4 9.2 12.3 21.8 15.8 15.4 12.4 19.7 21.9 15.6 14.7 12.4 15.5 6.8 17.2 12.4 14.9 7.7 8.1 19.2 19.4 19.8 19.9 18.9 9.3 17.0 10.1 20.1 22.6 17.9 9.5 11.8 16.5 17.3 10.3 15.0 13.6 13.8 12.5 10.4 20.2 10.4 12.5 6.8 13.7 8.7 13.3 13.6 14.0 12.8 15.9 13.5 13.1 13.3 15.0 13.8 5.3 9.0 13.6 9.6 11.8 11.0 16.0 22.2 18.9 20.7 15.0 15.0 15.2 15.8 17.2 13.7 LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 103.5;fHDF/TERT166: 157.7;HSkMC: 38.5;U-138 MG: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043930 Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" 290000 "Endoplasmic reticulum" "HPA043930: " "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavourable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavourable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavourable (3.32e-4)" 33.8 1.8 1.0 7.2 1.2 0.0 37.4 0.9 0.9 16.1 11.7 0.1 4.1 3.8 6.3 20.1 11.1 7.6 12.8 21.4 1.2 1.3 6.5 2.4 20.6 4.3 0.9 1.1 15.7 6.0 0.8 1.5 14.8 1.6 11.2 3.0 3.2 3.4 3.5 12.7 11.3 4.5 9.5 1.5 7.7 4.0 10.6 0.1 0.7 10.8 4.2 2.7 36.9 10.4 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.1 0.0 0.2 0.1 18.0 21.3 0.0 103.5 21.8 8.0 28.2 0.1 0.0 0.0 2.4 157.7 0.0 0.4 0.2 17.2 0.0 0.3 0.0 2.0 0.8 22.8 0.0 0.0 38.5 0.4 13.3 0.5 10.0 0.0 0.0 9.3 0.0 0.0 0.0 0.7 0.3 0.0 0.8 0.0 0.4 0.0 0.0 0.5 7.3 0.0 0.6 0.0 0.0 0.8 52.4 3.5 31.0 1.4 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 1.0 1.2 0.9 0.9 1.2 1.3 0.9 1.1 1.6 0.1 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23297189-23425328 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 107.9;BJ hTERT+ SV40 Large T+ RasG12V: 62.4;fHDF/TERT166: 69.9;TIME: 58.2;U-87 MG: 108.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 8 "pons and medulla: 22.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" Nucleoplasm "CAB025848: , HPA036257: , HPA056542: " "unprognostic (9.48e-2)" "prognostic unfavourable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavourable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavourable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavourable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavourable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 37.8 2.7 1.2 14.5 1.6 0.6 22.4 2.9 1.6 16.9 18.4 1.0 12.2 5.8 11.8 9.1 11.5 4.1 5.4 7.2 1.2 1.3 4.3 4.1 6.2 7.5 1.9 0.7 15.6 4.4 1.3 2.2 38.0 22.7 8.4 3.8 1.6 5.6 9.7 6.2 4.3 10.7 27.3 10.9 8.3 7.7 4.1 0.7 1.6 4.3 8.0 8.6 19.1 6.4 1.9 1.3 3.0 0.7 2.1 2.8 0.7 6.2 16.6 5.0 4.0 13.7 22.7 2.2 107.9 34.9 49.5 62.4 0.1 0.4 1.2 0.8 69.9 5.2 0.2 9.2 26.2 0.2 0.9 0.0 2.3 0.1 27.8 0.0 0.4 20.1 0.4 18.4 2.4 41.3 0.0 0.2 16.3 3.4 0.0 0.1 3.2 2.6 0.2 4.1 0.0 14.4 0.0 0.1 1.3 13.5 0.7 0.9 0.1 0.1 58.2 46.1 12.2 18.7 14.2 0.4 0.0 3.3 108.2 0.1 47.9 1.9 0.7 3.0 1.6 0.3 0.8 1.9 0.6 1.3 0.5 0.9 0.8 2.8 1.6 2.1 0.6 1.3 0.2 0.7 1.2 1.6 2.9 1.0 1.2 1.3 1.9 0.7 22.7 0.7 LOXL3 ENSG00000115318 "Lysyl oxidase like 3" P58215 2 74532414-74555690 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Oxidoreductase "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 26.7;U-138 MG: 47.1;WM-115: 101.0" "Cancer enhanced" "Detected in many" "melanoma: 15.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 11.1;non-classical monocyte: 8.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035281 Approved "Secreted to extracellular matrix" 15000 "HPA035281: AB_10601766" "unprognostic (7.54e-2)" "unprognostic (2.53e-2)" "unprognostic (5.34e-3)" "unprognostic (4.55e-3)" "unprognostic (6.85e-2)" "unprognostic (1.96e-1)" "unprognostic (1.68e-3)" "unprognostic (6.84e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "prognostic unfavourable (7.97e-8)" "unprognostic (1.22e-2)" "unprognostic (7.33e-3)" "unprognostic (7.09e-2)" "unprognostic (3.38e-2)" 7.9 7.1 6.3 8.5 5.0 15.9 9.7 2.9 6.5 6.6 8.4 13.1 2.2 5.1 10.2 7.5 4.1 5.8 8.0 10.8 4.5 5.0 3.2 2.0 6.8 8.0 5.7 6.7 4.2 3.3 2.3 3.9 18.8 7.4 4.4 4.8 7.8 3.6 5.5 1.6 2.1 4.9 10.2 9.7 12.3 3.7 3.5 4.8 0.6 3.0 3.4 2.9 6.1 6.0 0.1 3.4 2.7 11.1 0.0 0.0 2.5 0.2 0.0 3.8 0.6 3.2 4.1 0.7 13.1 26.7 6.4 6.1 4.4 0.2 0.0 0.1 13.4 0.1 0.4 0.3 3.8 19.8 0.0 3.1 0.2 0.0 1.0 0.1 3.2 4.2 0.0 16.9 0.7 0.1 0.1 0.3 1.1 0.6 0.0 1.1 2.1 0.1 0.3 0.4 0.0 0.0 0.1 1.8 2.4 0.0 0.1 2.7 0.3 0.2 0.0 47.1 1.6 0.2 0.1 0.1 0.1 0.0 17.7 1.2 101.0 0.1 5.6 0.3 0.0 11.1 0.0 0.1 0.0 0.0 3.4 0.1 0.0 0.0 2.7 0.0 8.7 0.3 0.0 2.5 6.3 5.0 2.9 6.5 4.5 5.0 5.7 6.7 7.4 4.8 LPA "LP, Lp(a)" ENSG00000198670 Lipoprotein(a) P08519 6 160531483-160664259 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Hydrolase, Protease, Serine protease" Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "liver: 43.4" "Cell line enriched" "Detected in single" 6 "RT4: 4.6" "Cancer enriched" "Detected in single" 38 "liver cancer: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016072, HPA060604" Supported "Secreted to blood" 78800000000 2900000000 "CAB016072: AB_2135240, HPA060604: " "unprognostic (2.16e-1)" "unprognostic (5.10e-1)" "unprognostic (7.75e-3)" "unprognostic (6.70e-2)" "unprognostic (1.60e-1)" "unprognostic (4.17e-3)" "unprognostic (1.59e-1)" "unprognostic (6.38e-3)" "unprognostic (3.63e-2)" "unprognostic (3.18e-1)" "unprognostic (7.45e-3)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (3.72e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.2 0.2 43.4 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 LPCAT1 "AGPAT10, AGPAT9, AYTL2, FLJ12443" ENSG00000153395 "Lysophosphatidylcholine acyltransferase 1" Q8NF37 5 1456480-1523977 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 35.6" "Cell line enhanced" "Detected in many" "BEWO: 34.2;EFO-21: 32.9;PC-3: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012501, HPA022268" Enhanced Supported "Endoplasmic reticulum,Lipid droplets" "Endoplasmic reticulum" "Lipid droplets" "HPA012501: AB_1845224, HPA022268: AB_1845225" "unprognostic (5.33e-3)" "prognostic unfavourable (7.11e-5)" "unprognostic (3.11e-1)" "prognostic unfavourable (3.67e-4)" "unprognostic (3.13e-2)" "unprognostic (1.26e-2)" "prognostic unfavourable (1.88e-8)" "unprognostic (5.90e-2)" "unprognostic (6.37e-2)" "unprognostic (2.08e-2)" "prognostic favourable (4.90e-5)" "unprognostic (4.89e-2)" "prognostic unfavourable (2.64e-7)" "unprognostic (2.60e-1)" "unprognostic (3.13e-1)" "unprognostic (1.52e-1)" "unprognostic (4.03e-1)" 9.8 5.6 5.2 9.0 5.7 5.1 7.4 9.2 9.5 5.4 7.5 2.9 4.5 3.9 7.0 3.2 3.2 5.9 5.8 4.3 5.3 5.2 4.9 3.1 35.6 8.5 3.2 3.7 5.0 5.4 3.1 5.6 10.0 4.6 5.2 2.3 13.6 4.5 4.4 3.5 3.2 5.9 5.5 3.3 28.8 9.4 3.0 2.9 5.8 4.7 1.4 8.1 6.6 10.6 0.9 0.7 2.4 1.7 1.7 3.6 0.6 2.0 3.0 0.5 3.2 0.3 0.5 34.2 7.7 0.4 0.4 0.3 1.1 0.9 6.7 32.9 0.2 5.7 0.6 0.2 0.2 16.2 13.9 1.6 4.8 2.0 0.6 1.7 4.6 0.6 0.1 0.3 0.1 0.4 3.6 1.2 0.0 4.2 6.3 2.6 12.0 22.9 12.0 0.5 4.9 1.3 2.7 4.3 4.2 6.1 5.5 1.8 2.6 2.6 3.8 0.6 7.5 2.3 2.7 4.3 4.1 1.5 1.4 2.8 2.0 0.0 0.6 0.8 3.6 1.7 3.6 0.9 0.8 1.8 0.7 0.7 0.1 1.0 2.4 1.7 1.2 0.2 0.8 0.6 5.2 5.7 9.2 8.0 5.3 5.2 3.2 3.7 4.6 2.9 LPCAT2 "AGPAT11, AYTL1, FLJ20481, LysoPAFAT" ENSG00000087253 "Lysophosphatidylcholine acyltransferase 2" Q7L5N7 16 55508998-55586670 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 33.5;HaCaT: 25.7;HL-60: 28.7;HMC-1: 47.8;WM-115: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 28.8;eosinophil: 49.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 49.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007891, HPA008433" Enhanced Supported Supported "Endoplasmic reticulum,Lipid droplets" "Endoplasmic reticulum" "Lipid droplets" "HPA007891: AB_1845223, HPA008433: " "unprognostic (1.43e-1)" "unprognostic (2.44e-2)" "prognostic favourable (3.43e-4)" "prognostic favourable (8.03e-6)" "unprognostic (2.91e-1)" "unprognostic (9.65e-3)" "unprognostic (8.12e-3)" "unprognostic (3.26e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (3.18e-3)" "unprognostic (9.16e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" 10.5 7.5 10.5 8.0 16.2 43.5 9.9 1.7 7.5 11.0 5.2 18.2 36.5 4.3 17.0 21.5 7.2 8.5 6.2 5.7 9.6 6.3 6.7 2.4 7.4 10.3 18.6 3.1 11.0 3.8 12.7 1.9 9.0 16.1 8.2 5.5 5.1 7.7 33.2 3.0 10.2 5.4 8.9 30.7 8.9 5.3 4.6 14.9 0.9 49.0 5.2 2.6 8.5 8.5 0.0 5.4 49.4 9.3 0.0 0.0 1.4 9.4 1.2 1.0 0.1 3.3 1.2 1.7 4.0 3.9 2.0 2.0 2.1 33.5 0.0 13.8 5.7 25.7 0.6 5.5 3.2 2.5 2.8 9.6 3.1 4.9 1.2 28.7 47.8 0.6 5.6 2.2 1.8 15.4 0.4 0.1 3.3 0.6 0.0 11.6 1.5 0.1 2.9 1.1 1.4 1.9 3.7 0.6 7.4 7.7 3.1 5.6 1.3 7.3 17.3 0.3 0.0 2.0 2.7 0.1 0.0 0.0 0.8 14.0 34.0 28.8 4.5 49.4 0.0 6.9 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 12.1 0.0 9.3 0.1 0.0 1.4 10.5 16.2 1.7 7.5 9.6 6.3 18.6 3.1 16.1 14.9 LPCAT4 "AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2" ENSG00000176454 "Lysophosphatidylcholine acyltransferase 4" Q643R3 15 34358618-34367278 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057321 Supported "HPA057321: " "unprognostic (2.79e-2)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (4.64e-3)" "unprognostic (1.29e-2)" "unprognostic (2.15e-2)" "prognostic unfavourable (9.99e-4)" "unprognostic (7.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.90e-1)" "unprognostic (1.23e-3)" "unprognostic (1.33e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.69e-2)" "unprognostic (3.44e-3)" 9.7 5.3 20.1 9.6 35.1 5.0 11.0 38.6 32.2 11.9 30.5 4.3 3.5 25.3 8.0 8.6 17.7 16.4 19.0 17.1 14.2 21.0 4.9 1.8 7.8 7.2 13.2 18.2 9.6 6.8 6.4 6.1 4.6 28.9 5.7 30.0 2.9 6.4 8.3 6.1 15.2 23.8 14.4 7.1 8.5 33.1 2.6 13.1 4.5 4.4 4.5 9.3 15.4 14.2 2.6 6.2 4.7 1.8 2.1 9.4 1.0 5.5 13.3 6.6 5.3 18.1 18.5 3.2 7.8 13.3 7.5 10.3 4.8 15.1 5.0 16.4 10.9 45.3 5.8 14.8 3.3 10.2 3.2 5.0 5.6 4.6 3.7 5.4 5.2 13.7 6.7 7.1 9.2 12.2 3.3 9.9 13.9 5.4 4.7 10.6 6.6 10.6 5.9 7.5 10.2 16.4 13.4 5.2 4.0 4.7 6.3 3.0 4.9 7.3 15.1 13.9 8.5 21.9 7.4 12.1 9.5 1.7 10.4 15.1 3.2 0.1 1.1 4.5 3.9 1.4 9.4 2.3 4.6 6.0 1.8 2.6 2.8 2.5 4.7 2.1 1.8 6.2 7.3 1.0 20.1 35.1 38.6 32.2 14.2 21.0 13.2 18.2 28.9 13.1 LPIN1 KIAA0188 ENSG00000134324 "Lipin 1" Q14693 2 11677595-11827409 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024591, HPA038021" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA024591: , HPA038021: AB_10669514" "unprognostic (1.97e-1)" "unprognostic (2.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.87e-2)" "unprognostic (9.17e-2)" "unprognostic (2.69e-2)" "unprognostic (8.20e-2)" "unprognostic (5.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (2.45e-3)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.58e-3)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" "unprognostic (4.02e-1)" 18.1 10.1 13.0 10.7 18.3 6.0 22.1 20.0 16.4 10.5 8.6 10.9 7.3 8.9 11.0 15.0 20.0 7.0 10.4 12.8 11.6 11.9 7.6 13.2 8.0 15.4 13.2 11.2 19.3 7.5 17.2 32.0 9.0 17.9 9.6 7.1 9.0 14.4 11.6 88.4 6.5 9.2 11.0 10.3 8.4 7.6 39.0 13.2 8.3 8.1 14.0 19.2 10.4 21.7 6.5 9.6 11.6 2.8 8.0 11.1 3.2 5.4 6.5 5.4 12.1 25.1 27.9 2.8 7.6 13.2 5.0 8.6 2.3 5.4 2.7 1.0 6.5 5.9 6.1 16.8 4.6 11.2 3.4 6.7 3.6 3.5 8.8 4.6 31.6 25.1 7.5 20.5 7.8 9.5 9.2 24.3 3.6 2.1 4.3 4.0 5.6 6.6 6.0 10.0 17.0 12.5 3.5 15.1 11.9 2.7 6.6 17.3 1.6 2.6 6.7 7.9 7.1 5.0 6.6 38.2 29.5 5.1 11.1 8.3 5.8 9.5 2.8 11.6 10.3 2.1 11.1 6.5 9.6 9.7 2.5 5.0 8.4 7.1 1.1 8.0 2.1 9.6 10.5 3.2 13.0 18.3 20.0 14.4 11.6 11.9 13.2 11.2 17.9 13.2 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013315 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 83.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 6 "granulocytes: 20.8;NK-cells: 10.1;T-cells: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: " "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favourable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 6.8 5.6 13.0 10.5 18.4 9.2 7.7 11.9 16.5 6.6 25.2 10.4 2.4 31.6 6.7 3.9 5.9 6.3 14.3 5.1 11.0 14.5 20.7 83.9 11.8 11.8 11.2 9.8 8.8 9.0 9.7 8.2 16.3 15.3 5.8 7.4 6.8 4.4 5.3 2.2 2.7 43.3 6.1 9.6 10.7 15.6 13.5 9.6 6.3 7.5 1.5 10.0 6.8 6.7 1.2 1.1 20.8 2.0 10.1 9.5 2.1 4.9 6.7 10.6 3.7 18.4 17.1 6.3 11.9 14.6 11.9 11.6 8.7 4.2 3.6 7.3 18.3 0.2 8.7 3.7 9.4 7.0 1.8 9.2 5.2 9.9 17.2 7.3 10.1 17.2 2.5 11.8 10.3 14.8 8.3 1.9 16.6 3.7 9.1 6.3 3.4 9.6 16.0 9.2 13.4 9.5 11.1 8.9 6.2 11.2 5.3 3.8 0.0 10.0 20.8 15.4 18.7 19.7 8.8 3.5 5.3 7.8 13.6 7.5 5.4 6.5 2.0 6.1 9.3 1.3 9.5 0.9 7.1 5.3 0.8 1.2 7.3 4.7 20.8 10.1 0.6 1.1 6.3 2.1 13.0 18.4 11.9 16.5 11.0 14.5 11.2 9.8 15.3 9.6 LPIN3 "LIPN3L, SMP2" ENSG00000132793 "Lipin 3" Q9BQK8 20 41340920-41360582 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 49.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "NK-cell: 6.3" "Group enriched" "Detected in many" 4 "granulocytes: 1.8;NK-cells: 6.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA051466, HPA052667, HPA070640" Approved Supported Cytosol Cytosol "HPA051466: , HPA052667: , HPA070640: " "unprognostic (2.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.68e-1)" "prognostic unfavourable (9.74e-4)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (6.91e-3)" "unprognostic (4.26e-2)" "unprognostic (1.74e-1)" "prognostic unfavourable (1.74e-4)" "unprognostic (4.29e-2)" "unprognostic (7.79e-2)" "prognostic unfavourable (1.14e-5)" "unprognostic (5.60e-3)" "unprognostic (2.02e-1)" "unprognostic (1.35e-1)" "unprognostic (3.37e-3)" 11.6 3.7 3.0 8.1 5.2 0.1 23.4 1.5 3.0 10.9 29.2 2.8 13.5 26.8 12.8 21.6 16.3 7.5 11.2 8.8 3.6 0.7 28.2 14.4 4.5 1.6 2.8 3.7 7.9 7.4 8.1 6.7 4.4 4.2 10.1 8.8 8.7 11.0 15.1 1.8 26.1 49.1 5.5 2.4 2.7 7.4 2.5 1.5 1.2 14.2 10.6 9.0 8.0 12.5 0.9 0.7 1.8 0.9 6.3 0.8 0.2 6.8 6.7 0.4 4.0 11.0 17.1 5.2 4.2 5.9 5.1 7.0 12.5 6.1 0.3 5.3 9.3 17.4 2.0 11.0 3.2 0.1 3.9 0.3 9.4 6.3 1.8 0.0 4.7 12.3 14.0 8.7 3.4 1.3 1.7 0.2 6.4 14.6 0.0 0.1 0.6 6.9 0.0 0.1 0.4 18.1 8.6 0.5 0.1 5.6 7.2 3.6 8.5 3.4 0.4 0.3 1.7 5.8 0.0 3.4 1.8 0.0 0.1 0.1 0.3 1.8 0.5 0.7 0.5 0.5 0.8 0.6 0.7 0.4 0.3 0.9 0.7 0.6 1.8 6.3 0.9 0.7 0.5 0.2 3.0 5.2 1.5 3.0 3.6 0.7 2.8 3.7 4.2 1.5 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967258 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease mutation, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 178.6;breast: 146.2;heart muscle: 121.4" "Cell line enriched" "Detected in some" 5 "AF22: 89.3" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Region enhanced" "Detected in many" "basal ganglia: 16.3" "Cell type enhanced" "Detected in some" "non-classical monocyte: 7.1" "Lineage enriched" "Detected in many" 5 "monocytes: 7.1" "Region enhanced" "Detected in many" "basal ganglia: 40.6" "Region enriched" "Detected in all" 4 "basal ganglia: 64.0" HPA048749 Supported Vesicles "Secreted to blood" 880000 Vesicles "HPA048749: " "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavourable (6.07e-4)" 178.6 4.3 2.0 11.4 16.3 0.6 146.2 3.9 8.0 1.0 16.9 0.3 27.3 0.8 1.3 1.1 1.1 0.7 8.2 121.4 2.8 2.3 4.8 0.6 20.7 7.0 4.5 0.7 2.7 1.8 32.6 0.9 7.1 1.7 0.9 1.8 8.4 9.2 85.1 53.8 1.8 3.1 1.3 2.8 0.8 1.8 0.7 3.4 0.0 2.7 9.7 1.0 3.2 6.1 0.0 0.7 1.3 7.1 0.0 0.1 0.4 0.0 0.0 89.3 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 14.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 7.2 0.0 1.6 1.3 0.0 2.8 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.4 2.0 16.3 3.9 2.3 2.8 2.3 4.5 0.7 1.7 3.4 LPO SPO ENSG00000167419 Lactoperoxidase P22079 17 58218548-58268518 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Antimicrobial, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 262 "salivary gland: 345.7" "Cell line enriched" "Detected in some" 9 "THP-1: 14.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028688 Enhanced Supported "Secreted to digestive system" "HPA028688: AB_10601909" "unprognostic (2.74e-1)" "unprognostic (5.12e-2)" "unprognostic (4.14e-3)" "unprognostic (1.56e-3)" "unprognostic (2.41e-2)" "unprognostic (9.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (2.40e-2)" "unprognostic (6.27e-3)" "unprognostic (6.32e-2)" "unprognostic (2.56e-1)" "unprognostic (0.00e+0)" "unprognostic (3.41e-2)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (1.22e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 345.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 1.2 0.0 0.0 1.2 0.8 1.3 0.7 0.8 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 1.0 1.5 0.0 0.9 0.7 0.4 0.6 0.3 0.5 0.9 0.7 0.6 0.2 1.2 0.6 0.9 1.3 0.8 0.3 0.8 0.4 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753118 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease mutation, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 82.4" "Cell line enriched" "Detected in some" 8 "NTERA-2: 16.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA070726 Uncertain "Endoplasmic reticulum,Golgi apparatus" "Golgi apparatus" "Endoplasmic reticulum" "HPA070726: " "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (4.75e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.65e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-4)" "unprognostic (4.49e-6)" "unprognostic (6.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" 0.9 0.8 2.2 0.8 3.2 1.8 1.4 0.7 1.1 0.9 4.2 3.0 0.8 3.7 0.5 1.2 0.5 0.9 2.3 0.6 3.1 4.2 0.6 3.3 1.0 0.5 2.9 2.4 1.0 2.9 0.3 1.0 0.3 8.9 1.6 0.4 82.4 0.5 1.6 2.3 1.4 11.1 0.3 7.0 0.7 0.9 2.9 3.1 0.0 4.9 0.2 0.6 0.5 0.7 0.9 3.7 2.0 4.5 0.6 0.3 3.9 0.6 0.5 0.4 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.8 0.6 0.1 0.1 0.2 0.5 0.3 0.3 0.1 0.1 0.0 0.1 0.2 0.1 0.2 0.1 0.3 16.1 0.0 0.1 0.0 0.1 1.9 0.5 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.4 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.2 0.5 1.0 4.5 0.4 0.3 1.6 0.3 0.5 0.3 0.3 3.7 0.9 0.3 0.3 2.0 0.6 0.5 0.5 0.2 3.9 2.2 3.2 0.7 1.1 3.1 4.2 2.9 2.4 8.9 3.1 LRRK1 "FLJ23119, KIAA1790, RIPK6, Roco1" ENSG00000154237 "Leucine rich repeat kinase 1" Q38SD2 15 100919215-101078254 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 26.3" "Cell line enhanced" "Detected in many" "Daudi: 23.1;Karpas-707: 17.0;U-266/84: 15.4;U-698: 15.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 3.2;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010537 Uncertain Supported Mitochondria,Cytosol "Mitochondria, Cytosol" "HPA010537: AB_1079283" "unprognostic (3.74e-2)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (3.72e-1)" "unprognostic (6.68e-2)" "unprognostic (6.35e-2)" "unprognostic (1.94e-1)" "unprognostic (4.75e-2)" "unprognostic (3.43e-2)" "unprognostic (3.34e-2)" "unprognostic (2.95e-2)" "unprognostic (8.50e-2)" "prognostic unfavourable (5.71e-5)" "unprognostic (2.92e-2)" "unprognostic (1.82e-2)" "unprognostic (3.13e-1)" "unprognostic (5.25e-2)" 6.1 1.9 4.5 26.3 3.9 6.5 5.0 2.1 8.1 6.4 8.0 5.9 2.2 2.9 7.9 6.0 5.4 7.1 4.2 3.4 4.0 1.5 2.7 1.0 4.7 15.0 4.5 4.0 6.3 5.3 2.8 2.3 4.4 2.5 7.1 6.5 2.8 7.7 6.8 1.6 7.3 8.5 5.7 3.7 11.1 3.9 5.1 3.4 1.2 3.5 2.1 17.4 7.5 6.7 2.3 3.3 3.2 1.1 0.0 0.0 0.1 0.8 4.7 0.0 0.0 7.3 7.5 0.0 2.8 2.1 2.6 1.8 0.8 2.1 23.1 1.0 7.7 4.7 0.6 0.5 1.3 0.4 1.1 7.0 1.0 0.0 0.5 3.7 5.4 5.9 1.0 1.7 1.5 4.7 1.1 17.0 0.5 0.0 0.0 2.3 0.2 2.0 1.6 0.4 6.3 0.0 0.0 0.0 1.6 1.8 2.7 5.3 0.3 4.5 5.4 0.0 0.8 1.0 0.0 8.7 15.4 15.0 0.3 0.5 4.3 0.0 0.7 3.2 0.0 0.3 0.0 2.3 0.0 0.0 0.9 1.5 0.0 0.0 0.8 0.0 1.1 3.3 0.0 0.1 4.5 3.9 2.1 8.1 4.0 1.5 4.5 4.0 2.5 3.4 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 40.4;lung: 50.4" "Cell line enhanced" "Detected in some" "A549: 9.7;ASC TERT1: 10.0;BJ hTERT+: 5.6;RPTEC TERT1: 10.7" "Group enriched" "Detected in many" 7 "lung cancer: 5.3;renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "neutrophil: 40.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 40.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favourable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 3.7 3.4 2.3 7.0 3.9 8.6 3.0 1.7 5.0 5.1 4.5 1.7 2.6 0.7 5.3 2.9 5.3 3.8 4.5 4.0 1.8 1.4 10.6 4.5 50.4 6.8 2.2 3.6 5.8 3.3 10.9 2.5 1.0 1.9 3.6 1.6 3.3 4.2 2.0 5.6 2.6 3.4 6.7 4.9 8.6 2.7 1.2 2.4 0.5 3.9 2.7 4.9 4.6 6.8 0.9 1.5 40.4 5.8 0.0 0.0 0.8 0.0 9.7 0.1 0.0 3.9 10.0 0.1 2.1 5.6 0.4 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 0.4 0.0 0.7 0.3 0.2 0.0 0.7 0.5 0.1 2.5 0.7 0.0 0.2 0.6 0.0 0.0 0.7 0.0 0.0 1.2 0.2 0.1 0.0 0.0 0.0 10.7 0.0 0.1 0.6 0.0 0.2 2.7 2.8 2.2 1.4 1.1 1.1 1.2 0.7 0.0 0.0 0.0 2.3 0.0 0.5 0.0 5.8 1.2 0.0 3.1 0.0 0.9 0.0 0.0 1.5 0.9 0.0 0.0 40.4 0.0 3.0 0.2 0.0 0.8 2.3 3.9 1.7 5.0 1.8 1.4 2.2 3.6 1.9 2.4 LRSAM1 "CMT2P, FLJ31641" ENSG00000148356 "Leucine rich repeat and sterile alpha motif containing 1" Q6UWE0 9 127451486-127503501 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021403, HPA021844, CAB037304" Supported Approved Cytosol Cytosol "CAB037304: AB_2138198, HPA021403: AB_1853366, HPA021844: AB_1853368" "unprognostic (8.83e-2)" "unprognostic (3.13e-1)" "unprognostic (7.48e-3)" "unprognostic (4.15e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.64e-1)" "unprognostic (5.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.72e-2)" "prognostic favourable (6.78e-6)" "unprognostic (1.27e-1)" "prognostic favourable (5.72e-4)" "unprognostic (1.94e-2)" "unprognostic (3.26e-1)" "unprognostic (9.07e-2)" "unprognostic (3.33e-2)" 9.5 13.6 15.6 10.1 17.2 15.3 9.2 24.2 22.6 10.7 18.0 15.3 10.9 10.8 12.6 17.6 12.3 11.0 11.9 18.7 13.3 17.3 11.2 15.6 11.7 11.5 13.5 22.7 16.0 9.6 17.6 11.8 9.2 17.9 13.6 8.6 10.2 11.9 13.7 20.4 28.3 11.1 16.0 18.7 12.6 12.2 6.1 13.9 5.5 11.6 9.6 11.5 17.2 12.9 4.1 5.4 17.4 6.6 1.3 4.8 3.2 5.7 8.7 5.3 10.1 8.9 8.8 8.3 5.4 6.7 8.3 6.2 10.0 5.6 9.8 5.5 7.5 18.9 6.4 11.3 3.3 10.4 4.9 5.3 11.3 8.7 7.1 5.8 11.2 5.1 9.3 5.7 10.9 8.9 4.7 10.2 3.6 14.4 4.1 5.1 5.0 8.8 6.7 4.7 15.3 9.0 5.0 9.7 8.0 3.5 12.0 7.0 24.6 3.1 10.4 5.6 5.7 7.0 3.6 11.3 8.4 1.6 9.2 5.4 2.9 14.6 4.9 17.4 4.4 6.6 4.8 4.1 3.0 3.7 5.4 3.1 1.5 2.0 5.7 1.3 5.5 4.6 2.4 3.2 15.6 17.2 24.2 22.6 13.3 17.3 13.5 22.7 17.9 13.9 LRTOMT "CFAP111, COMT2, DFNB63, LRRC51" ENSG00000184154 "Leucine rich transmembrane and O-methyltransferase domain containing" "Q8WZ04, Q96E66" 11 72080331-72110782 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Hearing, Neurotransmitter degradation" "Methyltransferase, Transferase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 49.8;testis: 47.8" "Cell line enhanced" "Detected in many" "T-47d: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA039949 Approved Uncertain Microtubules Microtubules "HPA039949: AB_10960708" "unprognostic (2.68e-1)" "unprognostic (6.43e-2)" "unprognostic (1.85e-2)" "prognostic favourable (7.70e-4)" "unprognostic (8.09e-2)" "unprognostic (9.07e-2)" "unprognostic (1.42e-1)" "unprognostic (1.90e-1)" "unprognostic (4.22e-2)" "prognostic favourable (5.36e-4)" "unprognostic (6.12e-2)" "unprognostic (8.43e-2)" "unprognostic (2.64e-2)" "unprognostic (1.58e-1)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (1.44e-1)" 3.5 3.7 10.6 2.0 11.1 2.1 7.1 3.7 8.9 7.1 4.2 14.0 6.1 3.2 6.0 13.6 3.5 49.8 5.3 2.6 8.8 7.6 9.0 6.2 6.2 2.6 7.7 8.5 8.5 7.0 7.1 8.9 4.4 10.6 7.5 6.2 7.3 4.3 4.7 5.2 4.5 2.5 4.8 7.7 3.2 3.6 47.8 8.9 3.1 9.3 2.4 3.5 3.5 2.6 4.3 4.2 9.2 2.9 10.1 6.2 2.0 2.6 9.8 6.2 5.0 5.4 4.8 1.5 3.1 2.5 2.8 2.5 4.7 14.3 3.4 4.8 5.3 5.3 4.4 7.5 3.2 6.4 4.3 2.5 4.5 3.3 0.9 2.0 2.7 2.1 3.8 4.3 3.3 1.0 2.7 5.3 4.1 9.4 6.0 4.0 3.1 2.6 7.3 6.3 5.2 11.0 3.2 5.8 4.5 6.1 14.1 7.5 27.8 2.4 4.7 3.0 4.2 8.0 2.1 5.7 6.2 4.0 2.9 1.7 3.3 2.3 2.9 5.0 3.1 2.8 3.2 4.2 3.3 2.6 1.7 4.3 3.0 3.0 9.2 10.1 1.8 4.2 6.2 2.0 10.6 11.1 3.7 8.9 8.8 7.6 7.7 8.5 10.6 8.9 LSS OSC ENSG00000160285 "Lanosterol synthase" P48449 21 46188141-46228824 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Isomerase "Cataract, Disease mutation, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 55.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032060, HPA032062, CAB034116" Supported Approved Cytosol Cytosol "CAB034116: AB_2138611, HPA032060: AB_10671085, HPA032062: " "unprognostic (2.78e-3)" "unprognostic (8.53e-3)" "unprognostic (6.95e-2)" "unprognostic (2.07e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (2.74e-2)" "unprognostic (1.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-2)" "unprognostic (1.68e-2)" "unprognostic (2.02e-2)" "unprognostic (2.34e-2)" "prognostic unfavourable (6.80e-4)" "unprognostic (1.92e-1)" "unprognostic (2.50e-1)" "prognostic unfavourable (3.07e-4)" 21.1 22.9 17.9 9.9 38.8 5.0 14.7 22.5 33.9 11.2 16.9 37.7 5.8 26.4 16.6 12.5 23.4 11.0 12.1 17.8 19.0 17.3 8.4 33.8 19.7 8.3 49.5 14.9 25.7 15.8 10.4 22.7 10.3 42.7 24.0 10.7 13.2 11.0 13.2 24.5 26.2 10.3 12.2 33.3 7.1 14.1 13.8 46.9 6.0 7.5 9.8 8.3 12.3 11.8 4.8 8.0 5.2 3.3 2.7 8.3 5.0 20.0 6.5 21.2 9.0 28.8 27.7 5.9 7.8 55.1 9.6 18.9 21.4 16.0 4.3 6.6 15.0 9.6 18.7 32.5 3.9 4.2 10.0 10.7 10.7 13.8 26.3 3.9 7.5 27.3 12.4 17.9 7.7 7.9 10.4 26.0 8.2 6.8 8.4 5.6 34.5 5.9 10.0 6.5 26.2 24.9 11.1 12.4 11.0 9.1 7.1 8.0 11.3 9.7 11.8 11.4 9.3 10.0 6.0 9.5 8.1 8.7 11.9 17.2 4.9 5.2 3.3 3.5 6.9 3.0 4.7 4.8 5.0 8.3 3.8 3.0 4.2 6.2 0.0 2.7 2.5 8.0 2.3 5.0 17.9 38.8 22.5 33.9 19.0 17.3 49.5 14.9 42.7 46.9 LTA4H ENSG00000111144 "Leukotriene A4 hydrolase" P09960 12 96000828-96043520 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008399, CAB015221, HPA017017" Supported Approved Nucleoplasm,Cytosol 85000000 "Nucleoplasm, Cytosol" "CAB015221: , HPA008399: AB_1852816, HPA017017: AB_1852818" "prognostic favourable (9.79e-4)" "unprognostic (6.62e-2)" "unprognostic (6.04e-2)" "unprognostic (1.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (4.25e-3)" "prognostic favourable (8.96e-4)" "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (3.38e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-1)" 27.9 33.2 11.2 21.5 16.7 55.7 19.0 24.1 15.6 27.2 29.1 13.1 16.7 27.6 27.6 14.1 53.4 22.7 14.5 19.2 10.6 12.2 27.2 19.4 68.0 33.4 12.3 11.3 49.9 28.2 21.2 31.8 11.3 13.3 29.6 17.8 20.7 21.1 16.1 20.6 23.6 41.2 21.5 13.3 44.3 22.1 13.7 11.5 29.2 38.8 22.3 43.1 30.1 25.2 20.6 35.3 6.1 84.2 14.2 9.0 54.6 23.5 25.4 35.7 21.3 31.0 34.7 15.6 9.9 29.3 19.6 22.8 18.6 20.5 52.9 12.4 14.7 31.1 29.2 40.3 26.8 18.1 28.3 19.4 16.3 22.5 18.3 10.2 11.8 33.0 34.0 27.0 33.1 38.7 11.8 9.3 28.2 16.2 26.8 31.5 41.6 34.5 25.2 26.6 30.5 35.9 30.1 18.5 21.9 20.0 23.4 21.4 29.0 12.5 13.8 8.3 14.0 11.8 10.7 12.6 21.8 24.5 5.9 18.6 6.5 0.4 76.0 2.2 4.5 84.2 8.4 15.1 6.3 5.8 35.3 20.6 9.0 6.7 6.1 14.2 73.2 8.7 6.3 54.6 11.2 16.7 24.1 15.6 10.6 12.2 12.3 11.3 13.3 11.5 LTC4S MGC33147 ENSG00000213316 "Leukotriene C4 synthase" Q16873 5 179793980-179796647 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Leukotriene biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 31.3" "Cell line enriched" "Detected in some" 10 "HMC-1: 50.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 8.5;eosinophil: 31.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044688 Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" Nucleoplasm "Endoplasmic reticulum, Cytosol" "HPA044688: " "unprognostic (8.94e-2)" "unprognostic (2.40e-2)" "unprognostic (9.35e-3)" "unprognostic (3.57e-2)" "unprognostic (1.24e-2)" "unprognostic (9.40e-2)" "unprognostic (4.53e-5)" "unprognostic (2.27e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (2.65e-1)" "unprognostic (1.98e-2)" "unprognostic (4.62e-1)" 9.0 6.7 3.5 2.8 3.5 8.6 4.6 1.7 5.0 6.9 5.0 9.4 5.4 3.6 8.7 10.4 4.2 13.0 15.7 11.3 3.9 3.1 6.2 2.3 28.3 8.0 6.8 4.2 5.8 2.4 2.0 3.2 2.9 4.3 5.6 1.9 3.3 7.4 11.6 2.7 3.5 5.7 4.5 6.3 6.7 5.0 3.3 3.9 0.8 5.3 5.6 3.2 3.6 3.9 0.1 4.5 31.3 0.3 2.2 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.4 5.1 0.0 0.2 0.2 0.3 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 8.5 0.2 31.3 0.5 0.3 1.7 0.1 1.2 0.8 4.5 0.1 0.2 0.5 0.1 2.2 0.0 0.2 0.1 0.3 3.5 3.5 1.7 5.0 3.9 3.1 6.8 4.2 4.3 3.9 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503638-41513887 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 15.1" "Cell line enhanced" "Detected in some" "HEL: 5.3;NB-4: 10.3;RH-30: 5.0;THP-1: 15.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "MAIT T-cell: 8.3;plasmacytoid DC: 7.0" "Group enriched" "Detected in many" 10 "dendritic cells: 7.0;T-cells: 8.3" "Low region specificity" "Detected in many" HPA059545 Uncertain Approved Vesicles Vesicles "HPA059545: " "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 1.0 0.5 0.5 5.1 1.6 3.1 0.5 2.0 3.2 0.6 8.2 0.5 1.9 10.6 1.3 1.1 1.2 0.3 2.0 2.2 0.5 0.1 3.5 4.3 15.1 0.6 0.5 0.5 1.0 0.5 1.0 0.7 8.9 0.5 0.7 4.8 4.3 11.7 0.5 2.0 0.9 10.7 0.5 0.5 5.5 8.3 2.4 0.8 0.5 0.7 0.5 2.2 0.6 0.7 0.7 7.0 0.0 0.0 0.0 8.3 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.1 0.6 0.9 1.3 2.4 0.0 0.0 0.1 0.7 0.0 2.9 0.0 0.4 0.2 1.4 5.3 0.0 0.0 2.3 0.0 0.0 0.4 0.4 0.0 0.1 0.0 2.0 0.0 2.0 0.0 0.0 10.3 0.4 0.2 0.2 5.0 0.1 0.0 0.0 0.5 3.3 0.1 0.2 0.0 0.2 15.8 0.0 0.0 0.2 0.2 0.0 0.4 0.2 0.2 0.0 0.5 0.9 0.0 0.0 0.0 0.6 0.0 8.3 0.7 0.5 1.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 7.0 0.0 0.2 0.5 1.6 2.0 3.2 0.5 0.1 0.5 0.5 0.5 0.8 LTN1 "C21orf10, C21orf98, FLJ11053, KIAA0714, LISTERIN, RNF160, ZNF294" ENSG00000198862 "Listerin E3 ubiquitin protein ligase 1" O94822 21 28928144-28992956 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029143, CAB034164, HPA055604" Uncertain Enhanced Cytosol Cytosol "CAB034164: AB_2180094, HPA029143: AB_10671360, HPA055604: " "unprognostic (3.67e-2)" "unprognostic (7.07e-2)" "unprognostic (7.78e-2)" "unprognostic (3.99e-1)" "unprognostic (1.42e-2)" "unprognostic (3.66e-3)" "unprognostic (5.38e-2)" "unprognostic (5.40e-2)" "unprognostic (9.98e-2)" "unprognostic (4.45e-2)" "unprognostic (2.85e-2)" "unprognostic (1.13e-1)" "unprognostic (9.87e-2)" "unprognostic (1.72e-1)" "unprognostic (8.22e-2)" "unprognostic (4.57e-2)" "unprognostic (1.52e-1)" 17.9 15.1 10.3 12.4 19.8 21.2 17.9 19.9 23.2 16.6 14.7 17.8 12.1 12.4 16.5 15.4 15.2 14.5 10.8 13.1 12.0 10.6 14.1 19.3 12.0 15.7 19.6 14.2 16.4 23.7 18.4 22.6 29.0 28.7 19.0 15.6 9.7 16.1 12.6 22.5 14.8 17.1 13.4 17.4 16.7 15.4 20.7 15.8 23.0 17.6 14.6 14.9 16.6 14.7 7.8 6.2 12.2 11.9 8.6 8.4 3.3 12.6 5.5 11.3 5.1 9.7 13.3 11.5 10.7 8.7 9.2 12.8 7.6 10.6 8.3 5.2 9.5 6.5 12.0 8.8 16.8 9.7 8.3 24.8 7.5 6.0 7.3 8.2 9.7 9.2 7.9 13.1 10.9 9.7 20.2 20.0 10.5 3.9 5.3 8.0 16.2 6.5 7.1 22.7 17.4 10.4 10.9 6.2 12.9 12.3 9.4 10.7 9.6 11.6 12.8 8.1 15.2 10.9 9.0 16.4 15.3 11.8 12.7 17.9 9.6 12.2 6.4 9.5 8.4 9.8 7.0 7.8 5.8 5.6 6.2 7.1 6.2 4.7 11.3 8.6 11.9 3.9 6.1 3.3 10.3 19.8 19.9 23.2 12.0 10.6 19.6 14.2 28.7 15.8 LVRN "APQ, AQPEP, FLJ90650, TAQPEP" ENSG00000172901 Laeverin Q6Q4G3 5 115962454-116027619 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 75.1" "Cell line enhanced" "Detected in some" "ASC diff: 2.3;ASC TERT1: 3.8;CAPAN-2: 1.8;SiHa: 1.5;U-266/70: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053254 Enhanced "Intracellular and membrane" "HPA053254: " "unprognostic (1.47e-1)" "unprognostic (3.38e-3)" "unprognostic (5.81e-2)" "unprognostic (2.97e-3)" "unprognostic (5.38e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-3)" "unprognostic (1.88e-2)" "unprognostic (2.23e-1)" "unprognostic (2.23e-2)" "unprognostic (3.83e-3)" "unprognostic (1.22e-1)" "unprognostic (1.67e-7)" "unprognostic (1.05e-2)" "unprognostic (5.94e-2)" "unprognostic (6.53e-2)" "unprognostic (3.31e-2)" 10.6 0.1 0.0 0.5 0.0 0.1 3.9 0.0 0.0 0.3 1.4 0.0 0.4 0.1 0.0 0.0 1.8 0.2 0.4 1.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.1 75.1 0.0 0.7 0.4 0.0 0.6 1.2 1.3 1.0 1.7 0.5 0.0 0.0 0.4 0.3 0.0 0.0 0.3 1.7 0.1 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.1 2.3 3.8 0.8 0.2 0.3 0.1 0.3 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 1.1 0.1 0.0 0.9 0.0 0.0 0.2 0.3 1.3 0.4 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.6 1.5 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879813-56014168 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.9" "Cell line enhanced" "Detected in many" "HEL: 56.8;HMC-1: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 36.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" 11000000 "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavourable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 8.8 6.8 4.5 34.0 6.3 33.6 11.1 9.5 4.1 5.3 10.5 5.8 7.2 15.6 3.4 7.8 7.2 6.7 13.7 8.9 4.8 3.6 6.1 13.8 34.6 70.9 7.7 2.1 5.3 9.8 3.1 4.9 19.1 5.6 5.7 6.6 6.3 14.9 8.5 2.7 3.4 16.2 6.6 8.5 69.4 7.4 3.6 5.1 3.8 9.4 5.3 25.8 10.7 7.5 8.4 9.2 36.8 26.5 1.9 0.9 2.7 12.6 7.5 1.7 0.3 0.1 0.0 13.7 9.7 14.2 6.1 4.3 5.2 4.4 12.2 4.3 3.8 5.9 7.1 7.2 5.2 19.8 7.1 56.8 2.3 1.8 1.9 5.7 57.7 0.3 2.5 0.1 4.4 8.2 30.0 26.5 0.9 0.7 0.0 6.0 10.9 0.8 0.9 2.8 1.5 3.9 6.0 1.1 22.0 4.8 0.0 2.0 1.1 13.4 9.6 0.0 2.8 0.0 4.4 8.9 3.2 27.6 0.6 11.3 0.4 2.1 7.2 12.3 0.9 16.8 0.7 8.2 0.2 0.3 6.4 8.4 0.1 0.4 36.8 1.9 26.5 9.2 0.0 2.7 4.5 6.3 9.5 4.1 4.8 3.6 7.7 2.1 5.6 5.1 LYZ ENSG00000090382 Lysozyme P61626 12 69348341-69354234 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 490.0;salivary gland: 1017.8" "Group enriched" "Detected in some" 6 "Hep G2: 126.5;THP-1: 65.3;U-937: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 490.0;myeloid DC: 308.1" "Group enriched" "Detected in all" 18 "dendritic cells: 308.1;monocytes: 490.0" "Not detected" "Not detected" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" 1500000000 2600000000 "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: , HPA066182: " "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favourable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 19.1 2.4 1.7 42.1 1.8 187.0 2.9 1.6 1.6 2.9 52.5 2.0 0.1 72.4 2.3 6.9 3.9 3.4 105.0 15.4 1.8 1.8 4.8 4.8 81.0 57.2 2.1 0.0 4.5 5.0 0.0 1.8 8.3 0.9 2.4 5.0 2.7 1017.8 2.8 1.8 2.1 95.0 1.8 2.5 34.2 212.1 1.6 0.5 24.5 2.4 207.7 75.7 6.6 2.4 1.6 308.1 21.9 490.0 2.3 1.1 407.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.2 0.8 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 0.1 126.5 0.0 14.8 7.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 14.4 0.3 0.0 0.2 0.2 2.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 65.3 0.0 0.0 0.3 0.3 0.1 0.3 0.1 0.1 0.0 70.7 0.0 7.5 490.0 5.9 0.7 102.3 1.1 1.6 0.4 0.5 308.1 0.4 0.4 0.4 21.9 2.3 17.6 6.5 0.6 407.9 1.7 1.8 1.6 1.6 1.8 1.8 2.1 0.0 0.9 0.5 LYZL6 "LYC1, PRO1485, TKAL754" ENSG00000275722 "Lysozyme like 6" O75951 17 35934518-35943699 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 51 "testis: 33.2" "Cell line enriched" "Detected in single" 5 "NB-4: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025734, HPA053073" Enhanced "Secreted in male reproductive system" "HPA025734: AB_1853444, HPA053073: " 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671386-58754477 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: " "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" 11.2 3.9 4.1 21.7 5.6 10.2 10.6 9.1 6.8 11.0 10.7 3.9 10.9 5.5 8.1 10.5 16.4 6.6 8.1 8.7 4.0 4.3 14.9 10.5 14.3 29.0 4.1 1.8 8.1 6.2 10.0 9.3 8.8 4.9 18.1 7.9 7.5 10.7 8.4 10.7 12.6 12.2 6.6 6.2 19.9 6.2 11.8 4.8 22.4 7.9 12.4 24.0 9.6 12.3 6.3 3.6 1.2 1.7 1.6 4.8 1.1 7.4 10.6 13.0 3.2 2.6 5.8 5.8 13.3 9.4 11.6 9.9 8.6 9.6 11.8 6.0 16.5 7.3 5.6 5.5 14.3 7.9 3.1 4.2 7.6 13.8 4.2 8.5 5.7 3.6 11.7 9.1 9.2 2.5 6.8 20.6 6.3 2.4 1.8 3.6 3.2 3.6 6.4 7.7 8.3 50.8 3.1 1.4 3.0 7.3 3.8 5.0 3.7 4.9 3.4 15.0 6.6 4.4 12.2 18.4 21.8 10.3 6.0 6.4 5.9 0.8 1.5 1.0 2.7 1.7 2.1 3.6 4.8 2.9 2.2 6.3 4.3 2.8 1.2 1.6 1.6 3.6 2.9 1.1 4.1 5.6 9.1 6.8 4.0 4.3 4.1 1.8 4.9 4.8 MAN1A1 ENSG00000111885 "Mannosidase alpha class 1A member 1" P33908 6 119177209-119349761 "Enzymes, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.2" "Cell line enhanced" "Detected in many" "ASC diff: 59.0;Hep G2: 41.4;Karpas-707: 46.2;U-266/70: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037058, HPA053198, HPA063561" Uncertain Supported "Golgi apparatus" 390000000 "Golgi apparatus" "CAB037058: AB_477183, HPA053198: , HPA063561: " "unprognostic (1.50e-1)" "unprognostic (7.36e-3)" "unprognostic (4.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.33e-3)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "unprognostic (1.68e-3)" "unprognostic (4.62e-1)" "unprognostic (2.37e-2)" "unprognostic (3.49e-2)" "unprognostic (2.25e-1)" "unprognostic (6.89e-2)" "unprognostic (3.40e-1)" 41.8 19.8 5.8 10.5 17.4 8.1 32.2 1.5 7.9 12.3 23.3 3.2 3.6 17.4 11.3 12.0 10.6 9.5 22.0 10.4 5.0 3.3 23.4 74.2 16.4 16.8 2.8 5.7 10.3 22.0 3.4 6.4 26.1 3.7 14.7 9.9 10.5 41.0 5.3 7.1 9.6 36.3 19.7 3.5 20.9 10.0 8.7 3.7 8.8 15.2 10.3 9.1 21.2 36.4 1.4 5.5 6.0 1.1 1.9 4.7 0.6 0.0 0.0 0.7 0.0 59.0 26.1 1.4 1.4 8.6 1.0 2.6 4.0 0.5 8.8 0.0 5.4 0.1 1.5 0.0 1.3 13.0 4.0 7.3 0.8 41.4 5.9 0.0 3.7 17.8 1.1 8.8 5.4 0.7 25.5 46.2 8.3 1.2 0.3 0.0 0.4 2.1 2.4 0.9 13.3 2.8 7.3 3.0 4.4 0.0 0.1 0.0 2.1 0.9 5.1 3.6 3.3 6.7 3.2 62.4 8.8 17.4 10.7 0.1 2.1 6.0 0.6 2.0 2.4 1.1 4.7 1.4 1.3 1.3 0.6 0.9 0.8 1.9 3.8 1.9 0.9 5.5 1.4 0.6 5.8 17.4 1.5 7.9 5.0 3.3 2.8 5.7 3.7 3.7 MAN1A2 MAN1B ENSG00000198162 "Mannosidase alpha class 1A member 2" O60476 1 117367449-117528872 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "placenta: 122.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034559, HPA057364" Enhanced Enhanced "Golgi apparatus" 1100000 "Golgi apparatus" "HPA034559: AB_10671229, HPA057364: " "unprognostic (2.24e-1)" "unprognostic (1.20e-1)" "unprognostic (2.92e-3)" "unprognostic (2.15e-1)" "unprognostic (3.11e-2)" "unprognostic (9.70e-2)" "unprognostic (1.95e-2)" "unprognostic (8.01e-2)" "unprognostic (8.19e-3)" "prognostic favourable (4.08e-4)" "unprognostic (1.41e-1)" "unprognostic (4.38e-2)" "unprognostic (6.84e-2)" "unprognostic (1.45e-1)" "unprognostic (7.39e-2)" "unprognostic (1.17e-1)" "unprognostic (5.08e-2)" 11.1 9.7 13.9 9.1 15.8 3.8 9.7 11.9 15.2 14.4 10.7 8.5 9.4 8.1 15.8 10.7 11.5 12.2 9.2 11.0 11.2 9.2 11.8 16.4 8.1 9.9 12.0 13.9 11.2 27.4 21.7 9.6 122.4 11.3 11.2 9.5 8.3 11.1 10.5 10.5 7.5 9.0 13.7 10.4 10.4 10.3 10.1 14.4 16.1 19.4 6.9 9.8 13.6 9.8 3.7 4.4 4.0 2.7 6.0 9.8 2.4 14.1 6.2 10.6 9.1 14.0 16.9 34.1 11.8 18.5 5.3 5.0 4.7 8.2 10.6 21.9 15.1 8.5 4.9 10.0 12.1 13.3 7.4 6.3 8.7 5.2 8.5 9.9 14.5 11.3 10.8 8.1 7.1 15.8 10.1 16.4 11.1 27.6 6.0 3.1 5.4 6.5 5.4 23.1 7.2 7.3 19.4 5.8 8.5 11.7 12.6 9.3 6.2 6.3 15.0 12.1 9.9 8.5 12.0 11.2 7.6 7.2 15.9 7.9 28.5 1.3 2.7 4.0 5.2 2.1 6.2 3.3 4.3 4.3 2.3 3.7 3.6 5.2 2.1 6.0 1.7 4.4 9.8 2.4 13.9 15.8 11.9 15.2 11.2 9.2 12.0 13.9 11.3 14.4 MAN1B1 "ERManI, MANA-ER, MRT15" ENSG00000177239 "Mannosidase alpha class 1B member 1" Q9UKM7 9 137086927-137109187 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051516 Approved Uncertain Vesicles 540000 Vesicles "HPA051516: " "unprognostic (1.21e-2)" "unprognostic (4.66e-1)" "unprognostic (1.25e-3)" "unprognostic (4.67e-3)" "unprognostic (2.27e-1)" "unprognostic (3.70e-3)" "prognostic unfavourable (1.45e-4)" "unprognostic (1.59e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-2)" "unprognostic (5.93e-3)" "unprognostic (1.75e-1)" "unprognostic (3.55e-2)" "unprognostic (2.28e-1)" "unprognostic (5.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.44e-3)" 20.4 25.4 19.7 13.5 23.7 9.8 18.6 21.6 36.1 24.3 21.6 24.5 20.6 19.8 22.7 28.1 23.1 28.9 25.9 19.5 20.5 21.5 24.3 32.7 20.4 19.9 18.6 25.2 24.2 32.6 23.6 25.1 30.8 18.0 21.2 12.0 22.0 32.7 23.1 12.2 25.4 17.8 18.5 16.4 22.2 21.8 30.3 18.2 19.9 25.1 12.7 19.3 21.0 16.0 13.0 23.0 16.3 24.4 18.0 21.9 18.5 7.2 17.1 5.9 16.9 22.5 19.4 19.8 12.3 26.1 16.5 14.6 8.3 22.9 6.6 41.4 20.6 25.0 3.5 11.9 3.0 9.1 6.0 2.9 15.4 9.6 21.2 5.1 11.4 22.9 22.6 9.6 8.1 10.9 8.0 10.9 11.6 14.7 5.4 12.1 7.9 17.2 3.1 10.0 20.9 13.2 3.6 6.9 6.2 18.2 19.4 12.6 21.5 10.9 15.3 24.4 9.1 18.0 14.4 4.4 3.6 4.3 29.4 6.5 21.0 7.9 20.1 16.3 21.9 21.8 20.5 13.0 17.3 20.6 23.0 11.0 17.0 17.0 5.9 18.0 24.4 16.1 21.5 18.5 19.7 23.7 21.6 36.1 20.5 21.5 18.6 25.2 18.0 18.2 MAN1C1 HMIC ENSG00000117643 "Mannosidase alpha class 1C member 1" Q9NR34 1 25617468-25786207 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 12.5;HSkMC: 46.0;U-266/70: 13.7" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 8.3" "Lineage enriched" "Detected in many" 5 "T-cells: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048352 Uncertain Uncertain Nucleoplasm,Vesicles 1200000 "Nucleoplasm, Vesicles" "HPA048352: " "unprognostic (2.75e-1)" "unprognostic (5.45e-3)" "unprognostic (5.71e-3)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (8.90e-3)" "unprognostic (4.78e-2)" "prognostic favourable (7.55e-4)" "unprognostic (1.80e-1)" "unprognostic (5.70e-2)" "prognostic favourable (4.79e-4)" "unprognostic (2.51e-1)" "unprognostic (9.09e-3)" "unprognostic (3.18e-2)" "unprognostic (7.23e-2)" "unprognostic (7.44e-2)" "unprognostic (5.18e-2)" 4.6 4.5 4.2 3.0 3.8 0.0 2.2 9.9 8.8 8.6 3.6 1.2 6.6 2.5 2.4 3.9 7.3 3.4 5.2 3.2 10.3 12.1 3.2 4.0 4.2 7.1 0.7 4.4 7.8 8.3 7.2 1.2 1.8 7.5 0.9 2.7 1.9 8.0 6.0 7.0 3.1 1.0 10.7 3.2 4.3 4.0 1.0 0.6 1.1 1.6 0.8 8.3 1.1 0.0 0.1 12.5 2.6 9.3 7.3 3.6 0.1 2.4 0.6 0.2 0.2 0.0 0.1 0.1 0.9 0.1 1.1 0.1 0.2 3.9 0.5 0.2 0.1 0.0 1.1 2.1 5.2 46.0 0.2 0.2 0.0 0.0 0.0 0.5 0.0 0.6 0.0 2.3 3.2 0.0 0.2 7.7 0.2 0.1 0.2 7.3 0.2 0.3 1.9 0.6 1.0 1.5 0.0 0.0 0.7 8.4 0.3 13.7 0.0 0.0 1.9 4.4 0.6 0.4 1.6 0.7 0.6 1.0 0.8 0.4 3.6 1.6 0.6 1.0 8.3 4.8 1.1 0.8 1.3 0.4 0.8 1.1 MAN2A1 "GOLIM7, MANA2" ENSG00000112893 "Mannosidase alpha class 2A member 1" Q16706 5 109689366-109869625 "Enzymes, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022377, HPA026896" Enhanced Supported "Golgi apparatus" 70000000 "Golgi apparatus" "CAB022377: , HPA026896: AB_1853512" "unprognostic (1.62e-2)" "unprognostic (4.06e-2)" "unprognostic (1.25e-2)" "unprognostic (6.96e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (4.20e-2)" "unprognostic (3.91e-1)" "unprognostic (2.90e-2)" "unprognostic (4.73e-2)" "unprognostic (1.23e-1)" "unprognostic (6.77e-3)" "unprognostic (2.03e-2)" "unprognostic (1.20e-2)" "unprognostic (1.11e-3)" "unprognostic (5.31e-3)" 7.6 17.5 10.9 7.7 21.8 5.7 7.4 1.9 13.2 8.4 11.2 46.8 2.4 17.2 9.2 1.8 7.7 6.2 10.6 4.2 11.7 4.8 9.5 20.7 8.5 7.8 29.9 10.4 7.5 16.7 20.1 3.4 8.7 19.8 4.7 11.9 5.6 9.0 6.0 8.7 7.0 14.4 11.2 23.1 6.9 8.9 7.5 30.6 15.0 9.0 1.8 7.8 10.9 6.2 3.3 2.7 5.8 6.7 0.9 5.5 1.6 7.2 6.7 8.4 3.6 16.1 14.2 31.4 16.1 26.6 9.2 16.6 7.9 11.7 5.2 10.4 20.9 8.6 4.5 16.7 20.1 5.6 3.4 10.6 5.0 7.2 9.1 4.8 5.8 12.1 6.9 14.7 19.5 18.1 2.8 30.5 21.6 3.6 9.0 1.3 6.0 2.4 3.5 13.1 23.0 7.3 11.5 1.2 1.1 7.6 6.8 4.6 6.7 4.2 19.3 18.2 8.0 9.8 10.4 16.3 21.1 4.4 14.0 6.2 10.1 5.8 2.9 0.9 3.0 3.8 1.9 3.3 4.5 4.9 2.7 2.9 5.5 4.8 2.1 0.9 6.7 2.5 4.1 1.6 10.9 21.8 1.9 13.2 11.7 4.8 29.9 10.4 19.8 30.6 MAN2A2 "HsT19662, MANA2X" ENSG00000196547 "Mannosidase alpha class 2A member 2" P49641 15 90902218-90922584 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.4;neutrophil: 10.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077930 Approved "Cytoplasmic bodies" 30000000 "Cytoplasmic bodies" "HPA077930: " "unprognostic (5.17e-2)" "unprognostic (9.80e-2)" "unprognostic (2.43e-2)" "unprognostic (2.41e-1)" "unprognostic (2.58e-1)" "unprognostic (1.86e-2)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "unprognostic (3.41e-1)" "unprognostic (2.27e-1)" "unprognostic (5.06e-3)" "unprognostic (1.09e-2)" "prognostic unfavourable (8.95e-4)" "unprognostic (7.55e-3)" "unprognostic (1.13e-1)" "unprognostic (8.36e-2)" "unprognostic (2.33e-2)" 17.8 12.1 15.9 11.5 24.3 58.1 17.3 33.7 31.2 7.2 9.9 52.4 6.3 12.0 8.9 9.8 7.6 8.0 9.4 22.7 17.8 14.0 8.1 16.7 13.3 12.4 31.6 19.7 9.7 24.0 13.0 15.2 12.4 31.0 9.2 9.0 17.2 20.6 12.6 41.8 14.8 13.0 7.6 33.1 19.1 12.4 12.7 28.3 3.8 13.8 2.7 9.1 7.5 10.7 1.5 2.1 10.0 3.2 0.1 1.4 1.5 5.7 5.9 4.2 10.0 12.7 3.4 8.2 4.2 3.9 4.4 3.4 4.8 4.3 0.8 10.4 4.9 6.5 4.4 2.4 2.7 14.2 10.4 39.2 9.0 3.2 4.2 5.7 21.3 2.5 4.6 5.3 4.3 5.7 14.7 5.1 2.0 7.8 3.7 11.3 1.4 1.8 5.1 4.0 6.0 5.5 13.8 10.2 5.9 5.8 10.9 8.2 5.1 18.7 4.9 3.6 3.9 4.4 5.5 8.0 24.4 2.1 4.2 8.3 6.1 8.4 1.6 0.6 1.4 1.1 0.9 1.0 0.6 0.8 0.3 1.5 0.4 0.4 10.0 0.1 3.2 2.1 1.3 1.5 15.9 24.3 33.7 31.2 17.8 14.0 31.6 19.7 31.0 28.3 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 42.1;intermediate monocyte: 39.4;myeloid DC: 35.2;non-classical monocyte: 28.4;plasmacytoid DC: 41.9" "Group enriched" "Detected in all" 5 "dendritic cells: 41.9;monocytes: 42.1" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" 3400000 "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavourable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 25.2 15.6 7.9 26.7 11.0 33.4 24.4 4.4 7.0 10.5 15.0 14.0 8.6 14.2 15.3 16.5 12.2 13.4 16.4 19.4 6.4 4.4 13.6 16.3 30.2 68.6 10.0 4.7 12.2 21.7 9.1 7.2 15.8 8.6 13.7 10.6 12.0 22.0 8.1 7.7 18.0 20.0 10.2 11.7 51.3 19.5 6.3 8.2 22.1 11.3 7.8 30.0 18.7 11.2 7.7 41.9 6.5 42.1 2.7 8.4 26.0 16.3 8.4 8.6 10.1 28.8 19.3 24.3 12.2 25.8 10.9 10.7 6.7 6.9 18.0 14.8 9.6 12.9 4.4 8.1 5.2 8.9 13.4 6.2 4.2 10.9 14.6 41.0 42.9 23.0 16.1 6.1 7.7 10.3 7.9 13.6 5.7 12.8 5.5 23.1 7.1 10.7 12.8 11.8 8.9 12.8 19.0 2.7 8.4 12.1 10.4 19.8 16.0 25.4 13.5 14.8 6.1 14.4 11.4 18.2 20.0 8.9 10.0 40.5 16.5 2.2 42.1 6.2 7.5 39.4 8.4 7.7 6.9 6.7 35.2 6.5 3.8 3.8 6.5 2.7 28.4 41.9 6.8 26.0 7.9 11.0 4.4 7.0 6.4 4.4 10.0 4.7 8.6 8.2 MAN2C1 "MANA, MANA1" ENSG00000140400 "Mannosidase alpha class 2C member 1" Q9NTJ4 15 75355207-75368630 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040627, HPA067407" Uncertain Enhanced Nucleoplasm 9000 Nucleoplasm "HPA040627: AB_10795490, HPA067407: " "unprognostic (4.68e-2)" "unprognostic (1.95e-1)" "unprognostic (3.84e-3)" "unprognostic (3.48e-2)" "unprognostic (3.85e-1)" "unprognostic (3.00e-2)" "unprognostic (1.26e-2)" "unprognostic (6.26e-2)" "unprognostic (2.47e-1)" "unprognostic (5.02e-2)" "unprognostic (1.06e-2)" "unprognostic (3.40e-2)" "unprognostic (4.87e-3)" "unprognostic (9.56e-2)" "unprognostic (1.33e-1)" "unprognostic (2.91e-1)" "unprognostic (1.39e-3)" 29.9 28.8 22.6 20.4 26.0 30.0 24.6 27.5 25.5 25.1 25.1 26.8 23.8 22.9 27.8 27.5 20.2 24.2 23.3 28.2 18.3 12.9 22.9 21.4 25.2 17.0 23.0 28.3 32.8 22.3 28.2 30.6 22.4 18.3 24.9 14.2 30.8 25.6 20.2 37.9 30.9 27.7 20.0 15.0 28.1 23.0 28.8 19.9 21.0 34.7 15.3 19.5 21.1 21.3 2.3 15.7 2.6 16.2 3.9 7.3 8.5 5.4 13.1 10.9 7.8 12.5 10.9 13.6 12.7 12.0 6.7 5.6 9.1 18.8 2.6 7.5 9.3 16.9 6.0 8.6 4.3 15.0 13.2 17.2 24.8 8.9 18.5 11.0 2.7 12.9 8.7 6.3 7.9 15.6 9.9 14.2 5.4 10.6 5.4 12.5 4.6 5.5 7.6 5.5 16.4 8.7 25.5 6.5 11.8 8.1 12.3 5.7 12.2 12.9 30.4 14.1 9.8 9.8 12.5 14.2 3.5 4.3 9.1 12.7 13.9 2.6 13.3 2.0 7.2 16.2 6.8 2.3 5.3 5.2 15.7 2.0 7.3 5.1 1.4 3.9 12.4 6.4 7.0 8.5 22.6 26.0 27.5 25.5 18.3 12.9 23.0 28.3 18.3 19.9 MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053478 Approved Supported Vesicles "Intracellular and membrane" 12000000 Vesicles "HPA053478: " "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.70e-1)" "prognostic unfavourable (7.56e-5)" "unprognostic (4.11e-2)" "prognostic unfavourable (3.74e-6)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (7.12e-2)" "unprognostic (4.81e-2)" "unprognostic (2.13e-1)" 12.7 23.5 8.5 12.2 11.9 8.6 17.1 13.4 8.4 12.1 9.9 12.9 11.7 8.1 11.6 13.6 9.3 11.0 15.5 12.1 8.7 8.6 11.8 10.3 17.7 20.2 15.1 6.2 16.7 18.1 25.1 18.4 25.0 10.8 12.0 10.8 12.4 27.4 11.4 5.4 7.8 14.0 14.2 15.3 21.3 14.4 4.6 13.5 9.4 19.2 3.6 12.8 17.9 12.6 3.9 9.5 25.2 11.6 3.6 3.1 3.9 7.3 4.1 2.0 1.9 39.0 18.1 5.1 5.1 10.1 2.2 4.4 5.3 8.5 7.9 6.9 7.1 3.5 5.2 11.3 1.8 5.5 2.1 4.5 4.6 8.1 11.9 8.3 20.5 15.4 19.3 9.5 7.9 4.1 7.5 8.2 8.0 3.3 2.0 8.0 2.8 3.4 4.1 4.7 2.2 6.4 8.7 1.3 1.0 6.1 10.5 7.9 15.0 5.7 3.1 6.1 3.0 13.6 2.7 4.3 9.0 0.8 11.0 3.7 4.4 6.2 11.5 25.2 1.8 10.6 1.4 3.8 3.1 2.0 9.5 3.9 3.0 2.0 10.1 3.6 11.6 2.3 1.6 3.9 8.5 11.9 13.4 8.4 8.7 8.6 15.1 6.2 10.8 13.5 MANEA "FLJ12838, mandaselin" ENSG00000172469 "Mannosidase endo-alpha" Q5SRI9 6 95577543-95609457 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011046, HPA011069" Enhanced Supported "Golgi apparatus" 87000 "Golgi apparatus" "HPA011046: AB_1079303, HPA011069: AB_1079304" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "prognostic favourable (3.04e-4)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (5.03e-2)" "unprognostic (2.98e-3)" "unprognostic (2.74e-1)" "unprognostic (5.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (9.07e-2)" "unprognostic (2.86e-3)" "unprognostic (5.18e-2)" "unprognostic (3.08e-1)" "unprognostic (9.68e-2)" "unprognostic (7.47e-2)" 18.0 8.1 6.0 6.7 6.9 2.4 14.4 8.3 6.0 9.6 9.5 5.0 5.8 7.7 7.5 8.2 11.5 7.2 7.1 9.3 6.5 6.2 14.6 44.9 9.8 12.3 8.9 6.7 10.4 8.0 10.9 13.5 7.4 7.8 9.2 8.0 4.5 8.1 7.6 3.8 5.9 9.5 6.0 11.6 13.2 10.7 7.1 6.9 17.9 11.7 5.9 9.7 11.2 7.5 6.6 3.4 8.5 5.7 3.8 10.4 3.3 3.7 3.2 12.2 9.9 20.3 23.9 4.7 10.6 9.7 6.2 9.3 3.6 9.5 7.2 13.2 6.8 6.2 8.4 7.0 14.2 12.4 7.6 9.8 3.0 5.9 7.1 12.7 8.7 23.6 8.2 7.3 5.1 14.4 15.0 16.8 13.1 2.6 7.4 5.4 1.8 3.2 8.9 12.2 10.7 9.4 6.6 9.8 5.3 5.9 4.3 3.7 6.8 12.0 13.0 6.2 4.4 11.1 10.3 12.6 7.4 8.9 11.0 11.2 14.0 8.5 3.3 1.9 4.8 5.7 6.8 6.6 5.9 5.5 3.4 3.3 6.9 4.6 0.7 3.8 4.9 1.3 10.4 3.3 6.0 6.9 8.3 6.0 6.5 6.2 8.9 6.7 7.8 6.9 MAOA ENSG00000189221 "Monoamine oxidase A" P21397 X 43654907-43746824 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" Oxidoreductase "Disease mutation, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 39.5;HHSteC: 74.2;HSkMC: 18.6;hTCEpi: 20.9;RT4: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 1.0;MAIT T-cell: 1.3" "Group enriched" "Detected in many" 10 "monocytes: 1.0;T-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009437, HPA054807, HPA059299" Enhanced Enhanced Mitochondria,Cytosol Mitochondria Cytosol "CAB009437: AB_2137260, HPA054807: , HPA059299: " "unprognostic (9.54e-3)" "unprognostic (1.63e-1)" "unprognostic (7.99e-2)" "unprognostic (3.07e-1)" "unprognostic (6.75e-2)" "unprognostic (3.32e-1)" "unprognostic (9.51e-2)" "unprognostic (6.89e-3)" "unprognostic (2.21e-1)" "unprognostic (4.29e-2)" "unprognostic (3.94e-1)" "unprognostic (3.54e-1)" "unprognostic (1.45e-3)" "unprognostic (1.16e-2)" "unprognostic (1.47e-1)" "unprognostic (4.04e-2)" "unprognostic (2.98e-3)" 72.3 11.0 8.2 10.2 7.8 0.3 35.2 3.3 6.1 12.4 85.7 2.8 10.7 53.6 12.5 6.2 36.6 12.0 14.7 37.8 6.7 8.3 77.8 45.9 34.4 5.2 11.1 6.1 14.2 24.4 9.6 1.5 79.8 8.7 26.2 39.9 6.2 49.1 12.9 12.5 11.2 90.1 23.6 3.4 2.1 19.3 5.5 4.7 0.0 68.6 9.7 3.9 35.3 35.1 0.0 0.0 0.1 1.0 0.0 1.3 0.1 0.0 0.8 0.1 2.3 39.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.0 1.4 5.3 0.0 0.0 0.5 1.6 0.1 4.2 74.2 0.0 4.0 18.6 20.9 0.0 10.9 4.7 0.0 0.1 1.3 0.6 0.0 0.1 0.3 1.2 0.0 0.0 0.1 5.3 30.6 0.7 1.8 0.0 0.0 0.0 0.1 0.0 2.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.3 0.0 0.1 0.3 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.1 8.2 7.8 3.3 6.1 6.7 8.3 11.1 6.1 8.7 4.7 MAOB ENSG00000069535 "Monoamine oxidase B" P27338 X 43766611-43882447 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 104.9" "Group enriched" "Detected in some" 7 "Hep G2: 20.2;SiHa: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "naive CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 6 "T-cells: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002328, CAB037200" Enhanced 3600000 "CAB037200: AB_1841012, HPA002328: AB_1854062" "unprognostic (1.19e-2)" "unprognostic (1.36e-1)" "unprognostic (5.16e-2)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.69e-2)" "unprognostic (5.61e-2)" "unprognostic (4.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (9.74e-2)" "unprognostic (5.35e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (1.90e-3)" 25.0 18.2 24.8 3.9 34.8 0.5 16.5 5.5 24.5 12.0 18.9 20.3 15.6 24.9 38.0 20.0 11.4 34.9 15.4 32.4 21.2 46.9 41.8 104.9 10.9 2.3 24.4 19.9 56.0 4.1 15.6 8.9 9.4 26.8 30.1 6.3 3.0 38.0 55.9 34.8 3.0 30.5 35.9 39.1 1.3 8.4 5.2 21.3 0.2 1.8 8.2 2.8 12.1 8.5 0.0 0.0 0.0 0.1 0.0 1.0 1.2 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 2.6 2.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 20.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 1.8 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.5 39.0 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 24.8 34.8 5.5 24.5 21.2 46.9 24.4 19.9 26.8 21.3 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386817-66492312 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" 62000 "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavourable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 28.6 16.9 33.9 19.1 54.1 29.0 23.6 32.5 48.4 12.5 12.1 8.4 10.2 10.0 11.8 16.5 22.0 10.6 14.4 19.1 49.2 26.4 15.3 53.1 16.4 23.3 17.6 31.2 13.5 11.7 23.4 12.0 15.4 17.2 14.4 12.9 9.1 13.2 12.4 39.5 12.3 10.9 16.9 17.4 14.5 10.8 7.8 12.6 12.6 12.3 9.7 27.9 13.6 18.7 4.6 16.2 5.5 8.2 8.4 7.9 2.7 33.1 15.6 31.5 13.1 19.0 14.3 18.2 24.1 20.6 26.2 23.4 23.5 27.3 30.5 29.9 19.8 29.6 29.4 35.2 30.8 24.5 17.5 9.8 16.4 12.7 15.4 12.9 14.6 11.0 21.8 18.9 28.1 20.4 17.3 39.0 38.1 12.8 10.3 16.8 16.1 13.7 11.7 19.5 27.1 25.4 14.3 19.4 10.8 19.5 15.3 20.2 13.8 11.0 28.1 34.1 20.9 24.0 35.7 24.2 43.0 19.4 36.0 22.8 15.9 3.2 8.2 5.5 7.4 8.2 6.7 3.0 6.6 6.9 8.3 4.6 7.9 4.9 3.9 8.4 7.3 16.2 4.9 2.7 33.9 54.1 32.5 46.9 49.2 26.4 17.6 31.2 17.2 12.6 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124129 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol Cytosol "CAB003835: AB_562312, HPA051993: " "unprognostic (4.39e-1)" "prognostic favourable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favourable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favourable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 23.9 33.0 35.6 27.6 36.1 46.7 30.2 31.2 43.4 22.6 38.8 24.6 27.0 70.9 21.8 23.2 32.8 21.7 27.9 41.4 33.1 31.0 22.7 42.0 24.1 44.5 34.4 29.2 30.8 46.0 18.9 29.7 21.3 26.1 25.7 24.3 21.7 41.5 24.0 134.9 27.4 56.7 19.0 25.2 25.9 28.3 42.0 20.9 44.1 26.2 42.2 29.1 20.0 26.9 11.4 10.7 28.3 10.6 11.3 12.1 4.5 36.2 40.0 21.9 30.7 30.3 36.6 21.9 23.9 32.0 32.7 29.7 34.6 19.7 31.0 22.6 27.2 26.2 17.1 25.5 25.4 26.3 20.8 11.3 21.8 38.2 46.5 20.8 23.9 40.4 24.9 22.9 30.6 28.9 21.6 61.3 27.5 45.4 41.1 29.2 25.1 29.1 31.5 14.4 35.4 28.5 23.3 29.7 29.6 21.9 30.4 74.5 23.4 35.7 25.5 26.9 23.3 68.6 36.8 61.7 37.3 21.7 41.7 37.5 45.9 15.2 9.1 28.3 11.9 10.6 9.7 8.9 9.7 12.1 10.7 11.4 8.9 11.6 14.4 11.3 8.7 6.0 9.2 4.5 35.6 36.1 31.2 43.4 33.1 31.0 34.4 29.2 26.1 20.9 MAP2K3 "MAPKK3, MEK3, MKK3, PRKMK3" ENSG00000034152 "Mitogen-activated protein kinase kinase 3" P46734 17 21284672-21315240 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018548 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB018548: AB_631927" "unprognostic (2.31e-1)" "unprognostic (6.39e-2)" "unprognostic (4.63e-2)" "unprognostic (3.68e-1)" "unprognostic (3.54e-3)" "unprognostic (1.60e-1)" "unprognostic (2.97e-2)" "unprognostic (1.35e-2)" "unprognostic (5.25e-3)" "unprognostic (1.88e-2)" "unprognostic (3.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.33e-1)" "unprognostic (6.48e-2)" "unprognostic (1.22e-2)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" 16.1 12.1 5.5 14.8 7.3 66.9 29.0 12.4 8.9 10.2 12.4 6.3 10.3 18.1 7.6 11.1 24.2 11.6 25.1 26.8 5.6 5.3 15.8 37.1 25.5 34.0 7.4 3.9 10.1 26.3 9.6 15.8 26.7 9.5 12.2 9.3 12.7 18.5 9.2 46.4 20.9 23.8 18.1 7.6 26.7 16.3 5.3 4.1 16.4 11.5 45.0 21.4 16.0 17.3 13.2 17.3 49.2 33.3 5.4 16.2 10.0 21.6 22.0 2.9 13.3 17.8 11.4 11.1 33.6 36.5 26.8 24.7 24.3 14.0 19.6 13.7 52.5 21.5 9.3 29.8 19.1 20.3 17.0 11.4 12.6 22.0 5.5 14.9 23.4 8.8 8.5 36.5 11.0 12.0 2.2 9.8 22.3 21.5 7.4 14.2 8.4 12.6 15.5 18.9 14.5 15.1 22.9 8.0 2.8 12.4 13.4 23.3 6.7 5.1 10.9 25.5 20.8 27.2 21.6 12.3 6.2 25.2 24.6 12.9 13.1 14.5 16.0 25.2 14.6 24.0 12.6 13.2 12.1 13.6 17.3 10.6 7.8 10.1 49.2 5.4 33.3 12.7 16.2 10.0 5.5 7.3 12.4 8.9 5.6 5.3 7.4 3.9 9.5 4.1 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020824-12143830 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: " "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 10.7 13.2 23.7 9.4 21.0 3.1 14.4 25.0 42.7 12.5 11.5 7.9 8.5 9.6 12.1 17.8 18.5 11.5 10.7 14.9 31.7 29.3 15.8 20.6 11.4 14.6 24.5 27.1 13.0 11.1 19.6 16.7 15.1 23.4 14.5 13.1 6.5 9.8 13.2 20.6 14.4 9.9 13.5 16.3 10.7 10.7 10.3 9.8 10.3 16.5 11.6 13.4 11.1 11.2 2.8 1.8 13.2 4.3 3.5 3.3 2.3 17.9 15.5 20.4 10.5 11.3 14.7 13.0 12.3 16.2 14.0 13.4 9.2 6.2 7.5 10.0 19.1 12.1 17.7 17.1 21.1 13.2 20.8 8.3 9.1 17.3 13.3 7.9 12.6 12.1 17.0 16.4 17.2 12.7 8.8 4.4 17.6 6.7 9.6 7.4 11.9 7.6 11.8 22.9 5.1 19.2 11.6 4.1 12.1 14.2 7.6 11.8 9.6 5.8 11.6 6.9 10.7 9.5 14.5 8.7 9.7 5.9 13.0 6.3 10.0 0.6 2.7 2.0 3.0 1.5 2.7 2.8 2.4 2.4 1.8 2.7 2.0 3.3 13.2 3.5 4.3 1.8 2.6 2.3 23.7 21.0 25.0 42.7 31.7 29.3 24.5 27.1 23.4 9.8 MAP2K5 "HsT17454, MAPKK5, MEK5, PRKMK5" ENSG00000137764 "Mitogen-activated protein kinase kinase 5" Q13163 15 67542709-67807123 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022094, HPA027347, HPA027755" Supported Approved Nucleoli,Microtubules "Nucleoli, Microtubules" "CAB022094: , HPA027347: AB_10599290, HPA027755: AB_10600883" "unprognostic (4.54e-2)" "unprognostic (1.87e-2)" "unprognostic (4.16e-2)" "unprognostic (9.06e-2)" "unprognostic (1.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" "unprognostic (3.73e-1)" "unprognostic (2.41e-2)" "unprognostic (2.83e-1)" "unprognostic (1.47e-2)" "unprognostic (5.41e-2)" "prognostic favourable (8.03e-5)" "unprognostic (1.68e-1)" "unprognostic (2.74e-1)" "unprognostic (3.99e-2)" "unprognostic (2.73e-2)" 18.6 22.2 20.3 13.8 30.9 14.6 23.7 25.0 25.4 17.0 19.3 17.2 19.9 14.7 17.4 11.3 13.5 16.2 14.4 18.8 17.1 16.4 14.2 15.5 13.5 27.9 12.6 11.5 29.0 21.0 34.1 14.4 17.7 22.2 15.9 14.8 15.6 15.7 18.5 28.5 18.7 15.0 19.4 17.2 13.0 15.4 20.3 16.2 40.2 16.9 9.2 11.9 17.0 17.9 6.6 10.2 10.3 7.3 11.7 11.2 5.5 5.5 14.6 8.8 10.3 13.0 22.8 6.9 5.5 11.2 10.4 11.4 5.8 9.9 9.1 11.7 9.2 8.3 14.9 8.8 8.6 13.1 14.9 12.3 10.9 6.3 16.4 7.4 7.7 15.6 11.7 7.5 17.1 13.7 10.8 15.2 8.6 7.1 12.1 8.8 12.3 7.1 12.0 10.2 15.1 6.3 10.1 5.5 8.6 6.2 9.2 22.0 11.5 14.6 11.4 10.7 7.1 7.4 7.4 21.5 25.3 10.6 14.4 17.0 7.7 10.3 7.3 6.6 7.7 5.6 11.2 6.6 7.3 9.0 10.2 6.2 10.4 9.5 1.7 11.7 6.2 3.9 7.4 5.5 20.3 30.9 25.0 25.4 17.1 16.4 12.6 11.5 22.2 16.2 MAP2K6 "MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3" ENSG00000108984 "Mitogen-activated protein kinase kinase 6" P52564 17 69414698-69553861 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 31.9;skeletal muscle: 55.6" "Cell line enhanced" "Detected in many" "A549: 23.9;HUVEC TERT2: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 9.3;neutrophil: 19.3;plasmacytoid DC: 31.9" "Group enriched" "Detected in all" 9 "dendritic cells: 31.9;granulocytes: 19.3;monocytes: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007744, HPA031134" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB007744: AB_562318, HPA031134: AB_10603016" "prognostic favourable (2.27e-6)" "unprognostic (2.24e-1)" "unprognostic (8.46e-2)" "unprognostic (4.10e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.61e-3)" "unprognostic (9.52e-2)" "unprognostic (3.67e-1)" "unprognostic (4.09e-3)" "prognostic favourable (7.52e-4)" "unprognostic (3.61e-2)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (9.43e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-2)" 4.5 2.0 3.2 8.6 5.9 10.1 14.0 13.7 7.5 19.8 21.5 6.2 4.7 7.2 4.7 3.1 3.4 3.3 5.1 2.5 3.9 3.5 4.1 8.6 2.6 10.3 5.4 4.1 2.7 8.5 0.0 3.2 1.1 5.3 2.8 22.8 5.3 4.0 4.6 55.6 2.3 7.3 2.3 6.2 5.9 5.4 2.1 5.4 13.7 2.8 4.8 5.1 3.0 2.5 2.3 31.9 19.3 9.3 1.8 2.1 2.6 0.1 23.9 10.8 13.0 4.7 2.5 1.6 0.1 3.5 1.0 1.5 0.7 1.1 0.6 8.8 0.5 1.2 3.7 0.5 0.3 0.8 1.9 0.1 6.7 6.7 4.6 1.0 0.9 11.9 0.3 0.3 0.0 17.2 0.0 1.7 0.0 0.1 12.5 0.4 7.6 4.4 4.5 1.1 0.3 4.8 3.3 4.8 7.3 1.0 0.9 2.2 3.3 1.3 3.0 1.3 1.5 1.1 0.4 1.2 1.3 0.3 1.0 1.5 1.0 0.8 9.3 1.6 1.2 1.1 2.1 1.6 1.4 1.5 2.9 2.3 1.6 1.5 19.3 1.8 0.4 31.9 1.9 2.6 3.2 5.9 13.7 7.5 3.9 3.5 5.4 4.1 5.3 5.4 MAP2K7 "Jnkk2, MKK7, PRKMK7" ENSG00000076984 "Mitogen-activated protein kinase kinase 7" O14733 19 7903843-7914478 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001633, CAB004262, HPA064711" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "Golgi apparatus" "CAB004262: AB_627925, HPA001633: AB_1079516, HPA064711: " "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (4.24e-2)" "prognostic favourable (8.54e-5)" "unprognostic (1.80e-3)" "unprognostic (2.55e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-2)" "unprognostic (1.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.54e-2)" "unprognostic (3.71e-2)" "unprognostic (6.05e-2)" "unprognostic (1.73e-2)" "prognostic favourable (1.56e-4)" 16.3 14.9 13.5 16.4 16.4 23.8 13.6 28.7 21.5 14.3 15.6 23.2 15.1 19.3 19.1 9.9 13.6 13.1 14.3 15.8 14.6 11.9 12.8 15.9 12.5 15.9 17.2 13.9 18.4 22.3 13.9 17.0 16.4 16.2 14.4 7.9 14.2 23.0 13.4 61.6 21.3 18.7 14.1 12.5 19.4 14.8 21.5 16.5 9.8 13.7 17.3 12.8 15.4 15.2 3.0 2.6 4.8 2.7 3.3 2.5 1.0 12.7 7.3 6.4 10.4 5.1 5.0 11.9 8.4 4.1 5.7 6.0 10.5 7.8 15.2 13.6 4.4 11.7 5.5 6.4 2.2 12.1 27.4 10.7 9.7 7.8 6.6 9.9 13.6 5.7 8.4 4.5 5.2 5.2 15.6 20.0 3.3 6.7 14.2 24.2 11.2 16.5 14.1 6.9 15.4 5.1 10.7 11.7 11.8 5.7 10.1 11.7 10.8 11.4 7.7 17.5 10.0 12.3 11.3 29.0 13.4 14.3 8.7 14.7 7.0 0.0 2.7 1.9 2.3 2.5 1.5 2.1 1.9 2.0 1.3 3.0 1.7 2.5 4.8 3.3 1.5 2.6 0.7 1.0 13.5 16.4 28.7 21.5 14.6 11.9 17.2 13.9 16.2 16.5 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815574-56896152 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 27.0;THP-1: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in many" 6 "olfactory region: 22.5" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol Cytosol "CAB004500: AB_627926, HPA046509: " "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 6.7 4.9 5.4 14.6 4.8 15.2 14.9 8.0 4.5 7.6 6.7 5.4 7.3 4.3 7.1 9.4 12.7 7.2 5.9 4.3 3.7 3.2 9.5 4.4 8.8 21.4 6.4 3.1 8.4 9.2 6.3 7.9 8.1 4.5 8.3 4.5 12.6 15.4 9.7 3.5 21.8 11.2 4.0 3.8 21.3 5.5 8.5 5.1 11.7 19.2 6.6 18.2 6.0 11.7 6.6 2.8 6.7 7.2 2.7 5.8 2.3 6.4 3.9 6.2 4.1 1.0 0.8 10.4 1.2 1.7 3.9 5.5 18.4 4.9 5.8 0.4 1.5 3.4 5.1 2.3 5.4 2.0 2.2 3.2 1.7 8.6 2.5 5.1 9.0 1.0 2.5 1.2 1.9 1.7 2.8 10.5 1.0 2.8 3.5 6.9 2.8 0.5 5.6 4.4 19.9 6.8 6.8 2.6 27.0 3.8 4.8 11.0 13.2 25.2 4.9 0.3 3.3 1.4 2.3 7.7 3.9 11.1 0.6 3.0 6.6 6.7 4.5 1.0 1.2 6.8 1.2 6.6 3.8 1.8 2.8 5.1 2.5 0.9 2.6 2.7 7.2 1.5 5.8 2.3 5.4 4.8 8.0 4.5 3.7 3.2 6.4 3.1 4.5 5.1 MAP3K10 "MEKK10, MLK2, MST" ENSG00000130758 "Mitogen-activated protein kinase kinase kinase 10" Q02779 19 40191744-40215575 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007039 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Nucleoplasm, Actin filaments, Cytosol" "HPA007039: AB_1079357" "unprognostic (2.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-3)" "unprognostic (2.03e-2)" "unprognostic (2.04e-1)" "prognostic favourable (8.69e-4)" "unprognostic (4.50e-3)" "unprognostic (1.80e-1)" "unprognostic (3.94e-2)" "unprognostic (6.13e-2)" "unprognostic (1.34e-3)" "unprognostic (4.62e-3)" "unprognostic (6.88e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-2)" "unprognostic (4.77e-3)" "prognostic favourable (2.13e-4)" 7.7 7.0 29.6 4.7 22.8 3.7 2.2 14.3 32.0 3.3 3.4 5.3 1.8 4.4 4.5 1.8 3.7 3.1 4.0 8.2 28.2 11.2 4.7 2.1 4.2 4.6 11.5 9.4 4.3 8.1 4.7 5.2 3.7 9.0 4.6 2.0 2.4 6.9 4.8 22.9 5.6 5.0 4.0 5.3 6.7 6.2 6.6 7.1 2.3 3.3 2.6 2.4 3.8 5.4 0.8 0.0 0.0 0.2 0.0 0.9 0.0 6.2 7.5 2.3 5.5 2.2 1.3 6.5 4.4 2.2 2.0 2.1 1.7 1.8 5.7 4.6 1.5 2.0 0.9 2.2 0.3 10.9 7.1 1.5 3.2 1.7 4.2 1.2 3.7 1.2 5.4 2.2 1.5 1.9 5.4 9.8 0.6 3.7 4.7 2.3 2.8 4.9 5.9 2.5 3.4 1.8 4.0 7.8 11.3 5.1 1.8 10.3 2.5 2.3 3.1 5.3 5.1 7.8 8.4 13.0 7.5 2.5 6.2 2.4 7.7 0.0 0.1 0.0 0.4 0.2 0.0 0.8 0.2 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 29.6 22.8 14.3 28.7 28.2 11.2 11.5 9.4 9.0 7.1 MAP3K11 "MEKK11, MLK3, PTK1, SPRK" ENSG00000173327 "Mitogen-activated protein kinase kinase kinase 11" Q16584 11 65597755-65615382 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 75.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010165 Approved Supported "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "CAB010165: AB_631936" "unprognostic (8.36e-2)" "unprognostic (1.17e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.87e-1)" "unprognostic (7.56e-3)" "unprognostic (3.10e-2)" "unprognostic (4.50e-2)" "unprognostic (4.30e-1)" "unprognostic (4.69e-2)" "unprognostic (2.77e-2)" "unprognostic (3.13e-2)" "unprognostic (2.01e-2)" "unprognostic (7.62e-2)" "unprognostic (1.95e-1)" "unprognostic (8.27e-3)" 23.2 10.8 11.4 23.7 21.2 14.2 27.4 7.9 13.8 8.6 15.8 29.8 6.1 31.9 11.0 8.1 14.7 11.6 12.0 11.6 13.3 8.1 16.1 31.2 21.1 14.4 30.9 8.2 8.4 12.5 8.3 10.3 14.7 16.7 13.4 8.2 15.4 13.5 9.5 11.9 13.7 31.9 8.6 17.7 28.8 16.9 8.6 19.0 8.9 13.6 7.6 12.7 8.9 75.8 2.3 7.6 13.8 12.0 1.8 3.5 5.6 16.5 14.6 7.9 8.4 2.5 3.2 8.1 6.4 4.5 7.7 5.3 14.6 16.0 6.2 23.7 5.0 14.4 4.7 6.9 2.8 13.6 6.0 17.5 10.0 17.4 7.0 10.0 26.5 5.0 6.7 5.7 5.2 21.5 7.5 12.5 4.0 20.4 11.7 18.9 8.6 18.7 19.5 5.1 12.6 7.2 14.3 7.1 8.0 7.5 21.8 37.5 17.4 16.3 23.9 11.8 12.8 17.2 11.3 8.0 9.0 5.5 13.8 11.6 27.3 4.3 7.7 9.2 2.4 12.0 2.4 2.0 2.6 3.5 7.6 2.3 2.0 1.5 13.8 1.8 11.7 2.3 1.4 5.6 11.4 21.2 7.9 13.8 13.3 8.1 30.9 8.2 16.7 19.0 MAP3K12 "DLK, MEKK12, MUK, ZPK, ZPKP1" ENSG00000139625 "Mitogen-activated protein kinase kinase kinase 12" Q12852 12 53479669-53500063 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.3" "Cell line enhanced" "Detected in many" "ASC diff: 28.4;HHSteC: 27.1;HSkMC: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 3.4;monocytes: 1.7;T-cells: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039936, HPA071996" Enhanced Approved "Nucleoplasm,Cell Junctions" "Nucleoplasm, Cell Junctions" "HPA039936: AB_10795239, HPA071996: " "unprognostic (4.01e-1)" "unprognostic (3.30e-1)" "unprognostic (8.89e-3)" "unprognostic (6.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.97e-2)" "unprognostic (3.61e-2)" "unprognostic (2.39e-1)" "unprognostic (2.70e-1)" "prognostic favourable (1.51e-4)" "unprognostic (8.50e-3)" "prognostic unfavourable (5.43e-10)" "unprognostic (1.65e-2)" "unprognostic (2.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" 8.0 8.7 12.3 5.8 16.0 3.0 5.1 40.3 20.6 14.1 6.1 7.0 7.8 3.6 15.1 5.8 4.6 11.5 16.1 4.2 9.4 7.7 4.5 1.4 8.8 4.5 6.4 14.7 13.7 1.8 3.0 12.7 7.3 10.8 5.9 4.6 9.5 2.4 13.5 1.2 4.5 4.1 16.9 5.3 5.3 3.9 6.5 7.4 2.7 4.3 1.4 3.2 11.3 6.4 0.3 0.6 3.4 1.7 0.6 2.8 0.5 0.2 7.5 4.7 7.3 28.4 15.2 0.6 5.1 9.6 5.6 5.6 0.1 0.9 1.7 2.9 5.4 0.0 2.1 3.4 2.2 2.5 2.6 1.8 3.8 0.0 27.1 0.0 1.9 27.0 2.4 7.6 4.0 8.7 0.0 8.1 5.3 3.3 1.8 0.4 1.6 2.8 2.6 3.2 0.4 2.8 0.0 4.7 6.4 2.7 3.5 7.2 2.4 4.7 6.4 5.4 5.8 2.4 1.3 3.3 3.7 0.0 8.7 3.3 5.2 0.0 1.7 0.0 1.5 1.3 2.8 0.3 2.1 2.3 0.6 0.0 0.9 1.2 3.4 0.6 0.4 0.3 0.4 0.5 12.3 16.0 40.3 20.6 9.4 7.7 6.4 14.7 10.8 7.4 MAP3K13 "LZK, MEKK13" ENSG00000073803 "Mitogen-activated protein kinase kinase kinase 13" O43283 3 185282941-185489097 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016497, HPA036691, HPA036692" Uncertain Approved "Nucleoplasm,Centriolar satellite,Cytosol" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA016497: AB_10670027, HPA036691: AB_10673661, HPA036692: AB_10670845" "unprognostic (8.95e-2)" "unprognostic (6.72e-3)" "unprognostic (9.46e-2)" "prognostic unfavourable (1.28e-5)" "unprognostic (5.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.61e-1)" "unprognostic (1.23e-2)" "unprognostic (9.04e-2)" "prognostic favourable (1.11e-4)" "prognostic unfavourable (7.27e-5)" "unprognostic (2.70e-3)" "unprognostic (1.54e-2)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (6.64e-2)" "unprognostic (9.31e-3)" 9.8 24.8 21.7 8.7 22.2 9.5 15.1 16.4 26.1 12.9 16.9 18.4 10.5 16.8 12.9 42.1 15.2 14.6 13.1 8.1 19.2 18.6 21.9 20.7 15.2 7.4 23.2 17.1 16.5 24.9 20.9 24.5 9.1 21.8 14.5 18.9 18.6 26.2 11.4 3.3 9.8 23.4 12.1 26.4 8.7 16.4 12.9 15.8 4.4 18.6 8.3 10.3 12.5 11.5 23.7 21.5 21.1 13.2 11.5 17.4 7.8 29.1 5.8 11.3 0.3 10.3 12.7 6.6 6.7 4.6 10.9 13.2 11.2 11.0 0.2 23.0 12.2 16.7 0.3 15.5 19.4 32.4 15.0 0.1 7.9 9.2 11.2 15.3 8.4 11.5 13.6 9.3 11.7 12.1 0.3 23.7 9.7 9.1 1.8 7.2 13.0 13.7 0.2 13.5 16.0 19.2 7.6 18.6 12.4 11.3 17.1 23.2 25.8 8.6 8.0 9.0 11.7 16.2 14.5 12.1 15.6 9.6 13.2 7.8 14.7 6.4 13.2 5.1 10.3 12.2 15.8 23.7 12.4 12.8 21.5 19.0 17.4 16.8 21.1 11.5 8.6 9.4 4.8 7.8 21.7 22.2 16.4 26.1 19.2 18.6 23.2 17.1 21.8 15.8 MAP3K14 "FTDCR1B, HS, HSNIK, NIK" ENSG00000006062 "Mitogen-activated protein kinase kinase kinase 14" Q99558 17 45263121-45317040 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 22.0;HDLM-2: 22.6;U-251 MG: 22.1" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027269, HPA027270" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "HPA027269: AB_10600302, HPA027270: AB_10600884" "unprognostic (1.05e-2)" "prognostic favourable (5.27e-5)" "unprognostic (2.71e-2)" "unprognostic (9.42e-2)" "unprognostic (5.31e-2)" "unprognostic (2.61e-3)" "unprognostic (2.70e-2)" "unprognostic (1.72e-1)" "unprognostic (3.40e-1)" "unprognostic (3.45e-1)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "prognostic unfavourable (2.78e-4)" "unprognostic (8.82e-2)" "unprognostic (3.49e-2)" "unprognostic (1.03e-2)" "unprognostic (2.28e-1)" 3.7 3.4 3.0 14.7 4.0 3.4 2.7 4.9 3.6 5.0 7.3 4.5 3.5 6.0 5.5 3.3 6.8 4.2 6.2 4.5 3.0 4.4 5.1 4.9 12.0 3.0 0.6 3.5 5.7 3.5 7.7 1.5 4.6 5.2 3.5 4.3 7.5 4.8 14.5 6.1 9.6 5.2 4.1 8.4 4.0 4.5 4.5 7.1 2.2 6.9 18.0 4.9 2.8 9.5 4.8 7.7 3.6 5.6 5.2 2.3 9.4 22.0 2.2 3.9 1.5 3.7 5.6 2.6 1.8 8.3 5.1 3.4 11.6 4.2 13.3 2.7 6.6 1.0 3.5 4.3 22.6 1.7 0.9 6.0 1.5 4.0 0.7 4.4 5.8 2.2 4.1 2.2 1.6 1.8 18.0 4.2 3.4 3.9 1.5 1.2 3.1 5.2 6.7 9.5 6.0 1.9 2.3 1.9 4.0 2.7 2.8 1.7 0.4 3.5 3.8 5.9 3.2 22.1 17.2 6.4 2.2 2.1 2.4 5.1 1.5 3.4 1.6 3.5 3.6 2.0 7.6 2.4 2.5 2.3 9.5 2.6 2.5 7.7 5.6 2.2 4.8 5.2 2.3 MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515261 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.3;brain: 13.2" "Cell line enhanced" "Detected in some" "A549: 3.4;HAP1: 8.6;HEK 293: 7.2;HEL: 2.9;REH: 4.4" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 6 "pons and medulla: 13.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004006 Approved Vesicles Vesicles "HPA004006: AB_1079358" "unprognostic (2.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.21e-2)" "unprognostic (6.56e-8)" "unprognostic (3.47e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-3)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (2.77e-3)" "unprognostic (4.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (8.20e-2)" 0.1 17.3 0.5 0.4 0.3 0.5 0.1 2.3 0.1 0.1 0.1 5.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.5 3.6 0.1 0.5 0.0 0.1 0.0 1.3 4.1 0.4 5.7 0.0 13.2 0.1 0.0 4.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 2.6 0.1 2.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 8.6 0.0 0.0 1.4 7.2 2.9 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 2.2 2.2 0.9 4.4 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.3 2.3 0.1 0.4 0.5 0.1 0.0 13.2 0.0 MAP3K19 "FLJ23074, RCK, YSK4" ENSG00000176601 "Mitogen-activated protein kinase kinase kinase 19" Q56UN5 2 134964491-135047468 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.3;fallopian tube: 23.9" "Group enriched" "Detected in some" 5 "RPMI-8226: 4.0;U-266/70: 2.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.8" "Region enhanced" "Detected in many" "pons and medulla: 18.3" "Cell type enriched" "Detected in single" 6 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 6 "dendritic cells: 1.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "midbrain: 20.2" HPA011388 Uncertain Cytosol Cytosol "HPA011388: AB_1848822" "unprognostic (7.12e-3)" "unprognostic (6.55e-3)" "unprognostic (6.96e-2)" "unprognostic (3.90e-3)" "unprognostic (3.63e-1)" "unprognostic (2.21e-1)" "unprognostic (1.96e-1)" "unprognostic (9.38e-2)" "unprognostic (1.09e-1)" "unprognostic (4.33e-1)" "unprognostic (2.02e-2)" "unprognostic (1.32e-1)" "unprognostic (4.04e-6)" "unprognostic (1.50e-1)" "unprognostic (4.13e-2)" "unprognostic (1.54e-1)" "unprognostic (2.83e-4)" 0.1 0.2 1.7 0.2 6.2 0.1 0.1 0.0 0.5 1.1 0.2 7.3 0.0 0.2 1.0 6.7 0.2 23.9 0.1 0.1 2.9 3.8 0.2 0.2 5.6 0.2 0.5 1.5 7.3 0.1 0.1 1.0 0.1 18.3 0.3 0.2 0.0 0.2 0.2 0.3 0.2 0.2 0.1 0.5 0.2 0.2 7.6 3.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.0 4.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 1.7 6.2 0.0 0.5 2.9 3.8 0.5 1.5 18.3 3.1 MAP3K2 "MEKK2, MEKK2B" ENSG00000169967 "Mitogen-activated protein kinase kinase kinase 2" Q9Y2U5 2 127298730-127388465 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 13.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021540 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA021540: " "unprognostic (5.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.58e-1)" "unprognostic (9.46e-2)" "unprognostic (1.02e-1)" "unprognostic (5.76e-2)" "unprognostic (7.19e-2)" "unprognostic (4.50e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.97e-3)" "unprognostic (7.56e-2)" "unprognostic (8.93e-2)" "unprognostic (8.88e-2)" "unprognostic (2.11e-1)" 18.5 14.5 13.7 20.1 14.5 41.0 22.6 20.1 16.3 16.6 19.6 12.7 18.9 18.8 19.8 18.0 13.4 15.9 18.6 13.3 12.5 10.2 15.5 27.6 20.0 28.5 17.9 13.0 20.3 15.4 23.8 21.2 13.9 12.3 13.6 13.1 12.2 18.1 25.5 24.5 19.4 22.5 18.1 14.9 17.0 18.0 14.9 14.3 25.8 22.5 13.7 16.8 17.1 20.3 3.1 5.1 13.6 2.9 2.3 2.1 1.1 16.3 7.0 5.6 5.6 7.8 10.4 9.3 10.2 11.1 10.1 8.2 8.3 7.3 10.8 17.6 14.5 13.9 8.9 6.8 11.3 27.0 6.9 10.0 12.6 7.3 9.1 10.0 21.7 9.3 7.6 12.2 15.0 4.6 4.7 21.6 9.9 5.9 11.7 7.1 5.7 9.1 7.7 10.5 8.0 4.1 15.3 11.1 5.9 14.8 9.1 9.2 5.9 7.7 10.6 19.8 18.6 9.1 13.8 22.4 16.1 11.1 9.5 6.6 8.5 4.0 2.9 2.0 1.7 1.8 2.1 3.1 1.6 1.7 2.4 2.6 1.9 2.0 13.6 2.3 2.2 5.1 1.4 1.1 13.7 14.5 20.1 16.3 12.5 10.2 17.9 13.0 12.3 14.3 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268010 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 96.1" "Cell line enhanced" "Detected in many" "U-138 MG: 47.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 13.7" "Group enriched" "Detected in many" 5 "dendritic cells: 13.7;monocytes: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavourable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 21.7 5.0 2.9 7.4 3.3 0.8 9.2 2.8 3.1 25.7 24.8 2.1 10.7 3.1 30.2 15.4 26.2 13.1 14.9 52.5 3.5 3.0 2.4 8.5 7.5 2.5 4.5 3.0 21.7 4.4 22.6 3.1 6.9 4.2 25.6 5.4 11.5 6.7 15.8 96.1 5.8 8.0 68.4 4.7 3.7 15.8 6.6 3.5 2.8 6.7 38.0 4.9 46.7 24.0 2.1 13.7 2.3 8.0 0.4 1.6 2.7 8.7 7.3 5.8 7.6 16.9 25.2 3.6 31.6 24.7 14.8 15.9 5.0 5.8 6.7 8.3 31.6 5.9 8.6 16.7 33.3 13.1 5.8 11.0 8.3 1.0 6.7 9.8 11.6 20.2 7.2 27.8 43.9 9.7 4.9 1.3 9.7 3.7 6.1 4.9 3.2 4.2 9.1 11.9 0.0 3.6 5.0 3.4 3.3 12.2 3.0 5.1 3.4 5.3 9.7 47.2 19.4 14.0 7.1 0.0 0.0 1.4 33.9 2.7 4.9 0.1 8.0 0.0 0.9 7.5 0.9 1.5 0.8 1.6 13.7 2.1 0.0 0.8 2.3 0.4 6.6 0.3 0.7 2.7 2.9 3.3 2.8 3.1 3.5 3.0 4.5 3.0 4.2 3.5 MAP3K21 "KIAA1804, MLK4" ENSG00000143674 "Mitogen-activated protein kinase kinase kinase 21" Q5TCX8 1 233327768-233385148 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 28.9" "Cell line enhanced" "Detected in many" "HEK 293: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 6 "NK-cell: 5.0" "Lineage enriched" "Detected in single" 6 "NK-cells: 5.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007636 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA007636: AB_1079392" "unprognostic (3.29e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.42e-3)" "unprognostic (4.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.82e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (8.21e-2)" "unprognostic (3.76e-2)" "unprognostic (2.23e-1)" "unprognostic (1.71e-1)" "unprognostic (9.22e-2)" "unprognostic (4.84e-2)" 0.6 3.2 2.0 3.4 2.2 1.3 2.2 10.0 3.3 1.5 11.4 0.6 9.1 9.9 0.8 5.2 2.4 3.9 3.9 0.7 1.3 2.1 12.5 13.3 5.6 0.5 0.9 1.7 0.8 28.9 4.4 2.6 1.0 1.2 1.3 6.0 1.0 3.7 2.5 0.4 2.7 17.2 0.3 0.9 0.7 10.1 12.4 0.6 0.5 2.4 0.8 1.3 1.1 1.6 0.5 0.8 0.1 0.3 5.0 0.2 0.1 7.3 12.5 0.2 0.0 0.0 0.0 6.3 0.2 0.0 0.3 0.5 6.9 6.4 0.7 5.2 0.1 3.9 9.4 3.8 0.8 13.6 18.0 0.1 7.0 0.0 0.4 11.9 2.9 0.1 5.1 0.2 7.3 0.4 0.1 2.4 0.0 1.6 3.8 4.3 8.9 5.5 0.0 0.0 13.1 8.6 3.1 9.2 2.5 4.3 0.2 0.0 3.7 3.8 0.0 0.0 1.2 0.0 7.3 2.2 2.8 0.0 1.2 3.3 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.8 0.5 0.0 0.0 0.1 5.0 0.0 0.2 0.2 0.1 2.0 2.2 10.0 3.3 1.3 2.1 0.9 1.7 1.2 0.6 MAP3K3 "MAPKKK3, MEKK3" ENSG00000198909 "Mitogen-activated protein kinase kinase kinase 3" Q99759 17 63622415-63696303 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007764, HPA035410, HPA035411" Uncertain Approved Nucleoplasm Nucleoplasm "CAB007764: AB_562314, HPA035410: , HPA035411: " "unprognostic (9.65e-3)" "unprognostic (1.33e-1)" "unprognostic (5.14e-2)" "prognostic unfavourable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (4.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.46e-3)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (2.79e-2)" "unprognostic (4.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" 23.9 11.8 10.5 20.5 15.0 24.8 19.1 26.8 14.9 22.2 21.8 15.0 14.0 8.0 24.5 13.2 16.6 18.3 20.6 37.4 11.3 8.4 17.1 12.4 23.1 21.4 14.4 9.6 21.6 11.4 16.9 12.3 21.0 11.9 18.4 8.3 21.7 12.8 18.5 19.6 15.4 14.7 20.4 13.2 30.4 16.4 26.5 12.3 12.9 15.5 12.8 15.4 19.0 26.8 1.9 3.5 18.3 8.5 1.1 2.6 2.3 10.1 7.6 9.7 9.4 18.6 15.0 4.4 10.0 11.0 12.5 10.1 3.5 2.1 10.9 7.1 19.6 3.8 6.3 7.1 7.9 9.5 13.9 8.9 10.3 4.9 9.7 6.8 9.5 10.7 4.9 15.5 8.2 30.3 5.4 14.5 9.9 7.1 12.2 7.1 6.0 8.1 6.5 24.8 7.1 4.5 4.6 5.0 11.9 6.8 8.2 8.3 8.2 6.8 27.2 32.0 8.5 17.3 12.1 14.4 14.6 4.0 6.9 5.5 8.3 8.8 8.5 10.4 2.2 8.3 2.3 1.5 2.6 2.1 3.5 1.9 2.5 2.5 18.3 1.1 8.2 1.3 1.9 2.3 10.5 15.0 26.8 14.9 11.3 8.4 14.4 9.6 11.9 12.3 MAP3K4 "KIAA0213, MAPKKK4, MEKK4, MTK1" ENSG00000085511 "Mitogen-activated protein kinase kinase kinase 4" Q9Y6R4 6 160991727-161117385 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007625 Uncertain Approved Cytosol Cytosol "HPA007625: AB_1853770" "unprognostic (3.05e-3)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-1)" "unprognostic (7.65e-2)" "unprognostic (1.35e-3)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-3)" "unprognostic (2.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.93e-1)" "unprognostic (6.84e-2)" 12.0 8.0 13.1 17.7 12.6 9.1 14.6 23.1 14.0 16.4 13.9 9.3 12.2 9.5 22.2 11.9 21.4 14.1 11.4 12.4 11.9 7.8 9.4 8.2 15.9 14.4 12.8 8.9 17.4 12.1 15.8 16.2 12.4 9.2 14.2 9.8 9.4 15.0 15.4 24.4 15.1 13.3 13.9 7.7 10.6 11.1 13.5 12.4 16.2 10.6 13.0 16.8 15.8 23.9 8.8 5.4 17.5 3.8 3.5 8.9 2.2 4.6 5.3 10.1 8.6 6.3 7.4 6.5 5.3 4.7 6.1 6.5 7.5 3.4 9.6 3.8 13.5 11.7 10.3 10.6 7.5 7.0 8.4 12.5 4.9 7.4 4.8 13.0 6.1 4.6 12.3 6.4 5.8 7.9 31.6 11.1 6.5 4.8 8.7 6.6 6.1 8.2 9.6 9.3 7.6 5.6 3.4 5.8 5.2 9.9 10.6 0.9 4.3 15.9 7.4 7.5 9.6 6.9 25.0 6.5 5.2 8.8 8.8 13.4 7.8 17.5 3.8 2.3 5.0 3.0 8.9 6.2 7.1 4.5 4.3 8.8 5.0 4.9 0.2 3.5 1.7 5.4 4.8 2.2 13.1 12.6 23.1 14.0 11.9 7.8 12.8 8.9 9.2 12.4 MAP3K5 "ASK1, MAPKKK5, MEKK5" ENSG00000197442 "Mitogen-activated protein kinase kinase kinase 5" Q99683 6 136557047-136792518 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 55.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007824, HPA063245" Supported Supported Cytosol Cytosol "CAB007824: AB_598175, HPA063245: " "unprognostic (1.37e-1)" "unprognostic (3.21e-2)" "unprognostic (2.85e-2)" "unprognostic (1.38e-1)" "unprognostic (3.19e-1)" "prognostic favourable (6.08e-4)" "unprognostic (8.76e-2)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "unprognostic (1.90e-2)" "prognostic unfavourable (5.91e-4)" "unprognostic (3.97e-1)" "unprognostic (3.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.72e-1)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 7.7 55.6 13.0 7.5 17.6 7.6 5.5 12.9 12.7 4.0 5.4 6.9 3.6 4.6 7.2 5.1 6.4 6.1 4.9 7.3 11.8 6.8 6.8 5.5 7.7 8.8 8.2 6.4 32.4 28.2 1.5 9.9 3.4 7.9 11.6 6.2 5.8 4.2 4.9 3.7 5.0 4.6 4.3 7.5 9.8 8.7 7.3 8.6 2.0 10.0 3.4 9.0 10.8 18.9 2.5 2.5 8.5 3.0 4.1 7.0 1.4 2.8 1.7 0.0 0.0 4.1 11.1 1.0 4.1 22.3 2.1 2.0 0.1 2.9 1.7 6.1 5.7 4.0 7.1 2.1 5.6 2.3 5.6 14.7 3.9 0.0 19.8 6.8 0.0 14.6 2.8 3.3 9.6 7.1 3.6 16.5 15.0 5.5 0.1 5.8 0.7 2.4 3.8 4.7 6.7 8.6 18.3 5.2 3.4 3.4 3.3 0.9 0.7 6.1 6.2 3.6 1.1 0.2 3.8 13.5 8.9 0.0 2.8 9.6 3.1 5.7 3.0 3.3 2.7 2.3 4.9 2.0 4.3 3.7 2.5 2.5 0.4 1.4 8.5 4.1 2.1 2.4 7.0 1.4 13.0 17.6 12.9 9.4 11.8 6.8 8.2 6.4 7.9 8.6 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27355184-27366892 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: " "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavourable (2.13e-4)" "prognostic favourable (7.26e-4)" "prognostic unfavourable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 37.5 6.3 7.4 6.9 8.6 1.3 22.1 12.6 8.3 19.9 9.0 2.7 8.9 3.3 13.1 10.3 25.7 12.8 12.4 14.9 6.2 2.6 13.6 5.0 21.7 5.5 11.4 1.9 11.7 8.3 8.2 15.8 7.3 9.8 13.9 5.9 15.7 11.5 9.7 6.3 63.9 6.2 16.0 11.7 8.7 9.0 6.7 7.0 0.6 12.0 16.1 14.3 14.3 18.3 2.7 3.3 5.1 6.9 1.1 7.6 2.4 7.4 6.9 6.2 6.9 8.7 15.3 1.6 9.3 5.4 7.0 5.3 2.0 10.0 0.1 8.3 14.1 11.8 2.1 6.5 3.5 6.2 5.1 0.5 16.0 3.1 2.7 0.5 0.6 12.2 15.9 7.3 2.6 4.7 2.3 4.1 11.1 18.4 0.3 8.4 1.9 5.7 2.7 4.1 1.7 10.5 7.8 2.3 3.4 9.8 8.6 7.3 4.6 6.4 9.8 17.6 7.4 19.7 4.8 3.3 4.1 0.1 15.6 6.1 5.1 1.8 1.5 5.1 5.3 3.3 7.6 2.7 5.5 5.9 3.3 2.3 4.4 3.6 2.4 1.1 6.9 0.0 5.6 2.4 7.4 8.6 12.6 8.3 6.2 2.6 11.4 1.9 9.8 7.0 MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587045 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: AB_1079359, HPA075335: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "prognostic unfavourable (3.51e-4)" "unprognostic (9.77e-2)" "unprognostic (6.51e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-2)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" 15.5 17.6 19.6 17.3 26.3 10.3 21.6 27.5 27.3 21.1 16.4 15.7 15.8 12.5 23.1 23.6 15.2 15.5 17.6 22.2 20.5 17.5 15.9 15.5 20.0 22.2 22.9 16.4 25.0 13.5 25.8 25.6 23.6 20.7 21.2 15.3 12.4 17.0 23.3 24.3 18.7 14.7 19.4 23.0 23.3 14.7 13.8 21.7 28.2 20.3 10.8 21.9 17.2 18.9 14.2 15.9 19.4 17.7 18.2 22.1 13.6 7.7 6.9 20.1 17.2 14.7 19.7 14.2 15.6 18.1 14.1 17.8 8.8 7.5 17.3 10.0 16.9 8.3 12.6 12.2 24.0 8.8 13.4 15.4 9.5 11.7 15.4 17.1 11.9 16.2 14.9 13.7 16.9 13.2 30.8 14.2 20.1 9.5 7.9 14.5 16.5 8.7 13.7 36.1 8.4 11.8 8.7 10.2 14.5 10.9 7.6 11.8 7.5 30.5 12.6 11.5 7.3 10.5 14.5 12.7 11.3 7.5 17.6 18.8 16.8 15.5 12.7 19.4 15.1 17.4 16.8 14.2 14.5 14.4 15.9 10.5 16.5 16.0 12.5 18.2 17.7 9.8 22.1 13.6 19.6 26.3 27.5 27.3 20.5 17.5 22.9 16.4 20.7 21.7 MAP3K8 "c-COT, COT, EST, ESTF, MEKK8, Tpl-2" ENSG00000107968 "Mitogen-activated protein kinase kinase kinase 8" P41279 10 30433937-30461833 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 104.6" "Cell line enhanced" "Detected in many" "HMC-1: 24.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005120, HPA017962" Supported Supported Cytosol Cytosol "CAB005120: AB_2140669, HPA017962: AB_1853776" "unprognostic (1.91e-2)" "unprognostic (2.94e-1)" "unprognostic (3.07e-1)" "unprognostic (9.29e-2)" "unprognostic (6.73e-2)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (3.36e-2)" "unprognostic (1.41e-2)" "unprognostic (8.04e-3)" "unprognostic (8.23e-2)" "unprognostic (2.96e-1)" "prognostic unfavourable (8.76e-7)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.63e-2)" "unprognostic (5.98e-3)" 28.0 7.6 3.6 15.6 4.1 104.6 26.1 1.5 2.6 8.2 8.4 2.7 11.3 3.4 11.5 16.5 13.8 19.5 15.3 20.1 4.3 2.9 6.3 7.6 29.0 33.7 4.3 2.0 9.8 3.6 2.8 4.1 27.5 8.3 7.9 6.8 9.4 6.1 18.4 8.6 15.3 9.6 23.4 9.7 25.6 10.7 6.7 3.6 2.4 7.0 13.2 17.2 13.2 15.6 19.6 13.8 23.7 16.8 12.4 7.8 4.0 7.9 7.1 1.9 4.1 10.3 8.7 9.1 2.0 11.9 4.4 5.3 4.9 18.5 5.2 5.1 4.2 14.9 4.5 1.9 1.6 12.0 2.3 9.7 12.1 15.7 8.7 3.0 24.0 10.8 1.1 4.4 0.8 1.9 4.3 7.8 0.7 4.5 0.1 11.6 0.7 2.5 0.6 1.6 3.0 4.4 16.1 0.2 0.8 7.1 6.1 0.9 2.0 6.4 0.1 2.7 2.3 9.7 0.3 11.9 11.1 1.5 3.9 13.2 0.1 17.9 7.0 23.7 7.8 12.0 4.3 9.6 1.7 4.9 6.6 19.6 0.1 3.0 16.7 12.4 16.8 13.8 0.4 4.0 3.6 4.1 1.5 2.6 4.3 2.9 4.3 2.0 8.3 3.6 MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell line enhanced" "Detected in many" "A-431: 17.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" 0.5 2.2 5.8 2.0 9.2 1.4 2.8 20.1 16.5 2.4 3.1 1.8 0.4 3.0 1.1 3.4 10.1 2.2 1.5 1.2 5.7 7.1 3.1 2.4 3.9 2.6 5.9 5.9 1.4 4.3 6.8 4.7 2.8 12.8 2.0 3.1 3.1 3.2 1.3 1.9 7.8 2.9 0.7 1.6 1.9 3.4 10.1 1.8 0.6 5.3 3.2 6.8 2.0 3.9 2.3 0.5 1.3 0.2 1.1 1.4 0.3 17.7 8.2 1.6 2.0 0.0 0.0 5.5 0.3 0.2 1.7 1.5 5.9 6.8 3.6 2.4 0.1 8.4 5.2 10.0 1.8 2.4 1.5 0.2 2.9 3.9 0.2 0.4 0.8 0.1 5.5 1.2 10.4 0.0 1.3 0.8 0.4 7.1 2.8 0.4 3.5 3.8 1.0 3.1 0.7 3.9 8.2 11.3 2.4 5.1 6.1 1.0 5.5 0.6 0.0 0.0 7.2 0.0 2.8 1.9 4.3 1.9 2.7 0.3 1.0 0.5 0.2 0.8 0.6 0.1 0.1 1.0 0.6 1.0 0.0 2.3 1.0 0.7 1.3 1.1 0.2 0.5 1.4 0.3 5.8 9.2 20.1 16.5 5.7 7.1 5.9 5.9 12.8 1.8 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 16.2;intestine: 16.9;lymphoid tissue: 39.2" "Cell line enhanced" "Detected in some" "Daudi: 20.5;HDLM-2: 20.3;Karpas-707: 21.1;REH: 11.2;RPMI-8226: 12.7;U-266/70: 16.6;U-266/84: 16.3;U-698: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007419, CAB007754" Enhanced Uncertain "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favourable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favourable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavourable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 1.6 0.9 1.2 31.4 2.3 6.3 1.1 1.0 1.2 1.0 3.1 1.7 0.1 2.1 0.9 1.4 2.6 1.2 2.9 0.9 1.1 1.4 2.2 1.6 3.9 23.0 2.3 0.7 0.8 1.2 0.2 1.2 1.4 2.1 1.6 1.9 2.0 4.4 0.8 0.5 1.2 16.9 0.7 3.4 34.4 2.3 0.9 1.3 19.1 1.9 1.4 39.2 3.1 1.3 16.2 15.9 1.3 6.2 3.7 14.6 7.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.3 0.0 0.0 0.0 0.0 0.0 20.3 0.1 4.3 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 21.1 0.0 0.1 4.9 5.1 0.6 0.0 11.2 0.0 12.7 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 4.6 0.0 0.0 0.1 0.0 0.0 16.6 16.3 25.8 0.0 5.8 0.0 1.3 3.2 1.2 13.4 6.2 12.4 16.2 11.2 14.0 15.9 10.7 6.2 8.7 0.3 3.7 3.4 14.0 14.6 7.3 1.2 2.3 1.0 1.2 1.1 1.4 2.3 0.7 2.1 1.3 MAP4K2 "BL44, GCK, RAB8IP" ENSG00000168067 "Mitogen-activated protein kinase kinase kinase kinase 2" Q12851 11 64784914-64803241 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007330 Enhanced Approved Vesicles Vesicles "HPA007330: AB_1079361" "unprognostic (1.66e-1)" "unprognostic (2.83e-1)" "unprognostic (3.07e-3)" "unprognostic (4.37e-3)" "unprognostic (2.67e-1)" "unprognostic (9.23e-2)" "prognostic unfavourable (3.10e-5)" "unprognostic (4.51e-2)" "unprognostic (3.65e-1)" "unprognostic (5.28e-2)" "unprognostic (1.24e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" 6.9 6.2 9.4 15.2 10.0 19.1 5.8 12.1 15.6 5.2 5.8 10.1 6.9 4.9 6.2 4.0 4.3 4.4 6.3 5.5 9.4 9.2 6.2 3.1 12.0 22.3 8.3 7.3 4.2 7.2 5.2 8.0 12.3 12.5 6.1 4.7 6.7 9.0 8.9 3.4 5.0 9.9 5.6 6.7 22.6 7.1 5.5 6.6 11.5 8.7 3.9 18.8 6.1 5.1 10.8 5.0 8.2 14.8 2.3 9.6 7.1 6.1 5.5 3.6 6.6 3.3 2.0 8.6 4.6 4.3 5.6 3.9 2.4 2.9 10.7 8.6 5.2 1.8 4.4 4.5 3.3 13.9 2.1 18.8 7.7 5.1 4.0 9.9 7.1 2.0 2.3 4.3 2.8 13.6 1.6 1.0 1.7 7.6 5.8 9.9 2.4 7.5 12.2 0.4 12.3 3.1 3.1 4.4 6.3 4.0 5.2 4.1 10.5 15.2 10.5 4.7 10.5 4.3 1.9 1.2 2.4 11.6 4.1 15.0 3.4 2.2 4.2 5.6 5.2 12.2 5.3 10.8 7.0 4.7 4.4 7.6 8.6 6.3 8.2 2.3 14.8 5.0 9.6 7.1 9.4 10.0 12.1 15.6 9.4 9.2 8.3 7.3 12.5 6.6 MAP4K3 "GLK, MAPKKKK3, RAB8IPL1" ENSG00000011566 "Mitogen-activated protein kinase kinase kinase kinase 3" Q8IVH8 2 39249266-39437312 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 40.8;RT4: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030380 Approved Approved "Nucleoplasm,Centriolar satellite" "Centriolar satellite" Nucleoplasm "HPA030380: AB_10601132" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (5.87e-3)" "unprognostic (7.34e-3)" "unprognostic (6.77e-2)" "unprognostic (2.57e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.66e-1)" "unprognostic (6.73e-2)" "unprognostic (4.33e-3)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (5.08e-2)" 19.7 18.9 17.6 15.4 17.6 9.6 17.8 37.1 19.6 19.2 16.9 14.6 9.8 13.7 23.5 14.8 11.1 15.3 18.7 19.5 15.4 12.5 26.2 15.4 15.6 5.8 15.4 13.4 24.6 14.0 25.7 24.6 30.8 14.4 18.6 14.1 17.9 13.3 15.7 33.0 17.8 17.2 18.6 15.3 11.5 26.1 21.0 16.5 9.4 25.9 11.3 7.5 18.8 32.6 0.7 0.5 2.5 1.9 1.0 1.3 0.4 9.7 6.1 40.8 6.4 6.6 13.4 11.2 8.7 11.1 8.6 7.4 5.1 4.9 2.1 9.8 5.9 5.3 15.3 7.7 13.2 2.4 6.3 3.5 4.3 11.9 17.3 1.5 5.8 11.9 7.7 11.2 12.1 7.4 4.5 4.0 11.5 5.3 3.4 2.3 12.3 9.3 3.7 13.3 1.6 11.4 37.8 7.3 8.3 5.1 8.2 22.6 5.5 2.2 6.0 6.7 8.0 6.0 4.7 6.1 3.4 0.7 8.3 2.5 7.8 2.5 0.7 0.0 1.2 1.1 0.1 0.1 1.2 0.9 0.1 0.7 1.1 1.3 0.0 1.0 1.9 0.5 0.6 0.4 17.6 17.6 37.1 19.6 15.4 12.5 15.4 13.4 14.4 16.5 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 81.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavourable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavourable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 27.0 5.0 68.3 21.1 56.3 32.1 35.2 14.5 50.4 13.2 7.8 47.5 2.1 5.4 14.6 6.7 18.5 8.6 18.0 22.2 70.5 40.5 6.3 16.8 13.2 25.8 65.3 21.5 12.6 8.3 9.5 4.3 25.1 40.2 7.6 9.6 6.1 7.7 5.7 16.1 8.7 6.5 14.8 81.2 11.7 11.0 20.3 49.1 13.2 8.3 6.6 29.6 13.5 16.3 4.6 6.3 14.4 3.4 1.1 3.7 1.5 18.8 14.3 30.7 14.6 29.1 52.3 38.6 24.0 19.8 21.5 17.8 23.7 25.1 27.5 20.9 35.9 7.8 9.7 21.1 21.5 36.8 6.6 20.6 10.8 61.8 24.6 9.8 0.9 46.9 9.7 53.0 23.7 55.8 13.3 0.0 56.4 10.3 22.7 6.1 15.6 22.8 27.5 21.0 0.1 14.3 6.6 12.0 20.0 16.5 0.0 17.9 3.9 17.8 70.1 42.7 18.3 12.3 28.5 0.0 0.0 16.7 27.5 12.5 31.2 6.9 3.3 0.0 2.4 3.4 1.8 3.5 3.3 1.7 1.1 4.6 2.5 2.7 14.4 1.1 3.0 6.3 3.7 1.5 68.3 56.3 14.5 38.9 70.5 40.5 65.3 21.5 40.2 49.1 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21754500-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.3" "Cell line enhanced" "Detected in all" "K-562: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069" Approved 250000 "CAB004229: AB_627547, HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavourable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 16.1 21.1 32.9 18.3 80.3 20.2 13.6 31.0 54.5 18.6 18.5 23.2 9.6 13.7 17.4 10.6 25.7 16.9 14.9 22.8 32.4 23.4 21.7 16.4 19.9 16.6 18.4 23.6 16.0 19.8 27.4 10.9 17.2 27.6 16.4 19.9 14.2 15.8 17.8 28.2 17.5 15.1 22.8 20.4 19.8 17.2 24.2 21.5 19.5 23.0 11.1 21.4 17.7 15.3 2.5 3.2 13.5 4.9 7.0 13.7 2.5 19.3 12.2 15.7 9.0 18.7 18.9 6.0 21.4 20.0 19.2 18.6 9.7 10.3 10.7 10.6 28.6 18.4 18.5 17.1 25.1 43.1 17.3 19.4 11.5 11.4 15.4 27.3 20.1 14.0 13.7 23.2 21.5 26.2 79.5 12.2 23.4 7.9 17.6 6.0 5.9 12.1 19.4 39.0 2.9 11.0 15.9 12.9 7.1 23.1 14.0 12.5 10.5 9.2 22.9 16.1 21.0 18.4 13.6 11.7 14.3 16.7 15.2 13.3 17.4 1.0 4.0 5.8 13.7 4.6 3.9 2.0 2.9 4.9 3.2 2.5 2.8 5.1 13.5 7.0 4.9 3.2 2.7 2.5 32.9 80.3 31.0 54.5 32.4 23.4 18.4 23.6 27.6 21.5 MAPK10 "JNK3, p493F12, p54bSAPK, PRKM10" ENSG00000109339 "Mitogen-activated protein kinase 10" P53779 4 85990007-86594625 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.3" "Cell line enriched" "Detected in many" 6 "AF22: 58.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022625 Approved "CAB022625: " "unprognostic (2.46e-2)" "unprognostic (4.36e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-2)" "unprognostic (5.17e-2)" "unprognostic (2.03e-1)" "unprognostic (4.59e-2)" "unprognostic (4.82e-2)" "unprognostic (3.81e-2)" "unprognostic (4.45e-2)" "unprognostic (1.18e-3)" "unprognostic (3.02e-2)" "prognostic favourable (3.11e-4)" "unprognostic (1.92e-2)" "unprognostic (1.44e-1)" "unprognostic (6.22e-3)" "prognostic favourable (5.57e-4)" 17.2 11.9 31.6 3.7 34.5 9.7 6.2 26.1 58.3 11.4 4.0 12.6 8.1 3.2 11.0 14.2 7.4 11.9 10.4 5.1 36.0 28.6 15.0 2.7 6.5 3.9 31.5 36.4 11.3 5.6 10.9 31.5 3.4 37.9 16.6 4.3 5.4 3.4 18.9 2.0 3.5 3.9 11.4 23.1 5.3 4.3 18.2 15.8 0.0 15.3 0.4 3.6 11.1 10.2 3.7 3.0 6.9 1.8 3.3 3.6 2.3 1.0 1.9 58.9 1.8 1.6 1.3 2.2 1.2 1.1 1.0 0.4 1.1 1.7 2.6 2.0 0.7 3.6 0.6 1.5 1.7 3.7 1.6 2.1 2.3 1.9 1.4 0.9 1.2 1.6 0.7 1.4 1.9 1.2 1.9 9.7 0.6 1.5 1.7 1.1 3.4 1.2 1.8 1.5 0.9 4.2 6.2 3.6 3.2 1.2 4.8 0.8 3.5 1.2 2.7 2.6 2.6 1.1 1.0 3.2 1.9 1.6 3.7 1.3 1.4 6.9 1.8 3.3 2.3 1.6 2.4 3.7 1.9 2.5 1.6 3.3 2.7 3.6 6.2 3.3 1.5 3.0 2.7 2.3 31.6 34.5 26.1 58.3 36.0 28.6 31.5 36.4 37.9 15.8 MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069" Approved Approved Mitochondria Mitochondria "CAB012961: AB_2533144, HPA045069: " "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.02e-1)" "unprognostic (5.84e-2)" "unprognostic (5.89e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-3)" "unprognostic (2.18e-1)" "prognostic unfavourable (6.02e-6)" "unprognostic (9.84e-2)" "unprognostic (4.25e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" 20.4 5.7 14.2 7.5 17.3 0.8 8.2 22.0 23.7 6.6 2.7 2.8 1.0 1.9 8.2 6.2 5.3 7.0 8.8 8.8 11.7 9.1 5.0 1.5 8.5 8.5 7.2 19.9 5.3 3.1 6.4 10.9 8.4 6.6 7.2 2.7 4.1 5.7 8.0 5.0 6.4 2.6 9.8 5.5 7.3 4.6 3.1 4.1 0.9 4.5 5.3 6.1 6.0 4.4 1.1 0.0 0.0 0.3 0.0 0.9 0.0 1.7 4.2 4.6 17.3 6.1 9.2 0.1 6.4 4.6 4.3 1.7 1.6 3.2 0.0 5.8 6.0 4.2 3.0 2.6 0.3 8.9 2.1 6.1 5.5 0.4 7.0 1.5 9.5 12.8 7.6 1.2 0.5 9.4 4.9 16.7 4.2 7.4 0.3 5.6 0.4 4.8 16.7 0.1 5.9 6.5 0.0 4.3 11.5 5.5 2.3 4.6 7.6 4.8 14.7 12.9 10.8 0.9 2.4 0.7 1.9 7.1 6.5 1.7 10.8 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.4 0.2 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 14.2 17.3 22.0 23.7 11.7 9.1 7.2 19.9 6.6 4.1 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261825 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 104.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 31 "NK-cell: 3.0" "Lineage enriched" "Detected in single" 31 "NK-cells: 3.0" "Region enhanced" "Detected in many" "cerebellum: 35.4" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB025483: , HPA054562: " "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavourable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 3.0 1.6 4.5 2.1 4.5 1.0 1.8 9.0 7.0 2.1 1.4 2.1 1.6 2.0 5.4 5.1 3.3 2.9 2.4 5.1 3.9 3.6 2.5 1.0 2.1 2.0 3.5 5.7 3.0 1.4 1.2 7.0 2.3 2.6 2.9 1.1 2.2 1.4 3.7 104.2 0.9 1.5 4.2 2.6 1.6 1.5 1.6 2.4 0.0 1.3 10.8 1.1 2.4 1.9 0.0 0.0 0.0 0.0 3.0 0.0 0.0 10.3 6.4 2.4 7.4 5.6 6.2 3.5 7.9 6.9 13.3 8.5 9.2 3.2 19.4 10.8 8.7 6.9 11.0 1.6 2.5 5.6 15.4 12.7 19.3 11.4 17.9 11.9 25.2 13.4 2.9 3.0 0.0 15.0 11.2 18.1 6.1 5.7 0.0 15.9 7.5 10.4 18.1 6.7 19.7 7.9 1.4 8.5 2.9 6.1 0.2 9.8 3.3 13.8 7.8 13.7 12.4 2.9 4.9 4.2 3.2 10.4 3.5 11.2 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 4.5 4.5 9.0 7.0 3.9 3.6 3.5 5.7 2.6 2.4 MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 45.7;RPMI-8226: 27.6;RT4: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 16.5;T-cells: 27.8" "Region enhanced" "Detected in some" "cerebellum: 6.5" "Region enriched" "Detected in some" 15 "cerebellum: 59.9" "HPA007667, CAB025854" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol Nucleoli "Nucleoplasm, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favourable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" 6.5 22.0 2.2 5.4 4.0 2.9 6.8 2.8 7.3 6.8 18.9 0.5 36.8 18.8 1.9 10.3 41.1 2.4 12.0 1.2 1.7 1.8 6.5 2.8 9.6 11.2 0.8 3.8 3.9 24.6 18.8 12.4 10.5 2.5 6.8 16.0 2.4 20.7 26.3 0.9 28.6 37.7 2.1 0.8 5.9 12.2 23.7 1.1 5.0 13.8 16.0 18.5 7.3 13.9 16.5 0.1 5.2 0.3 2.8 27.8 6.7 19.3 0.1 0.3 0.2 1.1 5.6 2.7 1.5 0.2 0.2 0.5 16.2 19.1 4.6 1.2 1.5 15.1 0.0 45.7 0.4 11.8 5.1 0.1 0.5 16.0 1.9 0.1 1.2 4.8 16.2 2.9 0.6 3.0 0.3 5.2 0.5 10.2 0.1 1.2 0.1 0.3 11.4 0.2 27.6 8.8 28.6 19.3 0.3 1.7 0.3 0.1 21.7 2.5 4.0 1.4 0.2 0.5 0.3 0.3 6.9 1.4 0.0 0.5 0.1 5.2 0.3 4.5 16.2 0.0 10.5 10.8 11.6 13.0 0.1 16.5 10.6 11.9 3.9 2.8 0.0 0.0 27.8 6.7 2.2 4.0 2.8 7.3 1.7 1.8 0.8 3.8 2.5 1.1 MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027677-36111236 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 32.1;neutrophil: 12.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" 7100000 "Nuclear speckles" Cytosol "CAB010285: AB_632140, CAB040578: , HPA051825: " "unprognostic (6.76e-3)" "unprognostic (6.28e-2)" "unprognostic (6.30e-3)" "unprognostic (3.30e-3)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (8.10e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-3)" "unprognostic (8.39e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" "unprognostic (3.66e-3)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.58e-1)" 21.5 20.6 11.7 18.4 15.5 49.9 20.7 26.5 18.1 22.0 20.5 12.5 11.9 16.9 38.8 12.1 24.0 18.9 16.0 16.4 9.3 9.5 16.0 29.8 21.5 29.0 12.0 11.3 17.7 18.5 15.0 27.2 27.3 10.2 23.4 18.3 17.0 16.7 16.5 21.2 25.6 22.5 26.0 10.6 35.5 18.2 11.1 10.3 34.1 20.9 17.6 20.8 25.0 30.0 2.3 4.0 32.1 4.9 3.0 2.8 2.1 18.3 10.1 10.9 17.5 24.8 24.8 24.0 19.2 25.0 22.8 23.8 24.7 9.5 14.9 19.1 21.1 13.2 18.0 16.6 23.9 16.8 14.3 34.4 14.4 20.6 13.7 21.6 20.8 17.4 16.2 16.4 16.3 25.8 19.0 18.7 15.5 8.7 22.2 26.0 6.7 10.1 26.4 17.7 13.8 16.1 25.3 8.2 7.0 17.3 13.0 20.1 15.3 40.4 18.1 20.5 11.9 12.9 17.6 9.2 21.0 14.9 9.3 42.8 16.8 32.1 4.9 3.0 2.4 3.5 2.8 1.5 2.2 2.6 4.0 2.3 2.5 2.4 12.3 3.0 4.7 1.9 2.6 2.1 11.7 15.5 26.5 18.1 9.3 9.5 12.0 11.3 10.2 10.3 MAPK15 "ERK7, ERK8" ENSG00000181085 "Mitogen-activated protein kinase 15" Q8TD08 8 143716259-143722458 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.9;epididymis: 27.6;fallopian tube: 29.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.1;HeLa: 14.0;MCF7: 13.6;T-47d: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "pons and medulla: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA002704 Approved "Nucleoplasm,Cell Junctions,Cytosol" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA002704: AB_1079307" "unprognostic (9.11e-2)" "unprognostic (1.38e-1)" "unprognostic (8.04e-3)" "unprognostic (2.94e-1)" "unprognostic (2.54e-2)" "unprognostic (1.14e-2)" "unprognostic (1.22e-1)" "unprognostic (6.09e-2)" "unprognostic (2.59e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-1)" "unprognostic (9.51e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (5.78e-1)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" 0.6 0.1 3.6 0.3 8.1 0.1 1.1 0.2 2.1 4.5 0.4 8.7 5.2 0.5 2.2 27.6 1.3 29.5 0.4 1.1 5.4 4.6 3.9 0.2 7.4 0.5 0.2 1.5 4.7 2.0 9.1 4.2 0.6 26.9 0.9 0.4 1.6 3.0 2.4 0.2 4.9 0.7 0.5 0.4 0.5 0.9 7.3 2.4 0.1 8.4 0.5 0.4 0.5 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1.7 0.0 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.2 7.1 0.0 1.3 0.0 5.3 0.0 0.2 0.0 1.1 1.6 0.0 14.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 13.6 0.0 0.0 2.0 1.1 0.0 2.9 0.3 0.9 1.3 3.9 3.9 0.0 2.8 0.0 12.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 8.1 0.2 2.1 5.4 4.6 0.2 1.5 26.9 2.4 MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 25.1;neutrophil: 11.3" "Lineage enriched" "Detected in many" 8 "granulocytes: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Approved Nucleoplasm Nucleoplasm "CAB002683: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (5.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (1.60e-1)" "unprognostic (4.70e-3)" "unprognostic (2.75e-1)" "prognostic unfavourable (1.11e-4)" "unprognostic (2.09e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-2)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" 24.9 18.5 63.3 15.3 43.2 15.6 21.1 24.8 52.0 21.3 45.1 30.4 6.3 39.7 24.2 11.4 44.1 28.7 25.6 21.2 37.1 34.0 13.4 8.8 23.3 13.1 33.8 27.4 32.7 13.0 26.1 15.2 27.6 27.6 20.1 36.7 26.2 17.1 18.3 13.9 18.7 49.2 24.0 27.8 15.9 33.7 11.6 19.5 8.4 20.5 18.7 26.0 18.2 22.2 1.4 1.5 25.1 2.7 0.8 3.1 1.4 13.7 7.5 16.1 9.1 40.5 53.8 9.0 10.3 25.6 16.4 19.6 9.0 27.8 13.9 10.2 28.8 5.1 13.5 12.1 16.0 26.3 15.7 4.3 8.3 15.0 40.7 3.1 11.9 33.1 7.0 18.7 8.4 41.6 5.8 17.9 21.6 36.3 14.3 5.0 4.3 6.6 17.0 9.6 31.2 14.9 8.7 14.2 10.1 5.9 20.8 6.0 13.6 7.6 29.4 10.8 9.3 12.3 3.5 20.3 9.3 7.1 21.6 6.7 7.6 2.4 2.7 25.1 0.9 1.9 1.4 1.3 2.1 1.6 1.4 1.4 1.5 1.6 11.3 0.8 1.0 1.5 3.1 1.4 63.3 43.2 24.8 52.0 37.1 34.0 33.8 27.4 27.6 19.5 MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560078-50731824 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.4;brain: 33.4;parathyroid gland: 43.5" "Cell line enhanced" "Detected in some" "HAP1: 3.0;HeLa: 4.4;NTERA-2: 3.0;SCLC-21H: 15.4;SH-SY5Y: 3.7" "Group enriched" "Detected in many" 5 "glioma: 15.2;melanoma: 3.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" 1.9 26.4 16.9 1.1 33.4 0.9 1.8 15.9 23.9 1.4 2.6 9.5 3.8 1.6 1.8 4.5 3.5 1.5 3.0 16.9 13.0 14.3 4.5 7.0 3.5 0.9 17.1 9.1 4.2 2.5 43.5 8.3 3.7 20.5 5.3 1.8 4.1 1.8 12.4 1.7 1.0 1.9 5.2 11.8 1.1 1.3 3.5 12.4 1.7 7.8 0.0 0.9 2.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 1.5 1.4 4.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.1 15.4 3.7 0.0 1.1 2.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 33.4 15.9 14.5 13.0 14.3 17.1 9.1 20.5 12.4 MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067372 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005184, HPA030262" Approved Supported Enhanced Cytosol Cytosol "CAB005184: AB_2140298, HPA030262: AB_10601868" "unprognostic (6.61e-2)" "unprognostic (1.75e-2)" "unprognostic (5.05e-2)" "unprognostic (3.40e-3)" "unprognostic (2.72e-1)" "unprognostic (5.52e-2)" "unprognostic (6.13e-2)" "unprognostic (2.32e-3)" "unprognostic (3.99e-2)" "unprognostic (8.54e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-2)" "unprognostic (3.27e-3)" "unprognostic (2.03e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-2)" "unprognostic (2.31e-2)" 11.8 7.4 14.4 10.9 23.2 25.6 13.7 33.0 24.5 16.3 18.7 12.5 9.3 16.3 15.9 13.3 32.3 8.2 17.0 9.1 13.3 15.9 14.4 32.6 12.6 9.4 13.1 16.8 11.5 8.5 12.2 15.3 13.9 23.8 10.5 18.1 9.5 17.9 11.4 27.1 24.0 26.2 17.8 14.2 9.2 15.7 25.7 13.0 11.7 13.4 22.7 12.4 18.9 22.4 4.9 4.2 3.0 4.5 6.5 7.9 3.6 8.7 11.8 23.3 8.9 7.2 11.9 17.0 12.5 12.6 11.6 13.7 14.1 5.3 12.6 8.8 16.0 12.4 17.9 23.9 15.9 7.7 5.6 18.8 7.0 22.3 17.4 14.0 40.2 12.7 43.9 14.0 36.4 10.9 24.3 21.5 14.7 19.7 9.8 11.0 8.2 5.7 8.6 15.0 20.2 11.1 36.9 11.4 10.8 10.1 8.2 18.3 7.5 20.9 10.8 13.9 15.0 9.0 16.7 11.2 32.9 15.6 17.2 20.6 17.0 3.0 4.5 1.2 3.8 4.3 4.7 4.9 5.6 4.3 4.2 2.6 5.4 3.8 0.6 6.5 2.8 1.9 7.9 3.6 14.4 23.2 33.0 24.3 13.3 15.9 13.1 16.8 23.8 13.0 MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB018561: AB_2140544, HPA031031: " "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.90e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-3)" "prognostic unfavourable (1.86e-4)" "unprognostic (5.67e-3)" "unprognostic (1.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (5.71e-1)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.5 15.0 6.4 7.3 7.6 9.2 11.8 12.5 7.9 13.4 15.3 7.2 6.0 9.2 13.1 14.1 17.3 9.4 11.8 8.2 5.9 4.7 10.8 4.8 9.9 9.2 8.2 5.2 25.4 5.7 7.3 7.5 12.5 6.7 14.0 6.9 10.5 7.8 12.3 7.5 13.1 11.2 13.8 7.1 13.2 8.0 13.3 7.5 4.5 8.6 11.3 10.6 12.7 15.9 2.2 2.6 11.5 7.4 5.5 4.7 3.0 4.1 6.5 5.4 4.2 27.1 11.3 6.3 5.6 5.2 7.8 7.2 7.5 0.7 2.5 4.6 9.7 4.6 6.3 5.1 4.9 4.3 4.8 1.2 4.7 3.3 11.7 1.1 4.2 11.9 3.6 11.8 4.2 5.7 2.2 0.9 7.7 2.7 8.3 4.4 6.2 4.3 4.5 7.9 1.7 2.6 2.3 2.4 7.2 5.7 0.5 2.9 3.5 1.4 3.2 8.4 6.2 9.2 3.8 1.6 2.4 0.6 9.7 1.0 5.0 1.0 3.6 11.5 4.7 7.4 2.5 2.2 2.2 4.1 2.6 1.4 2.1 2.6 1.3 5.5 6.5 1.7 1.0 3.0 6.4 7.6 12.5 7.9 5.9 4.7 8.2 5.2 6.7 7.5 MAPK8 "JNK, JNK1, PRKM8, SAPK1" ENSG00000107643 "Mitogen-activated protein kinase 8" P45983 10 48306639-48439360 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004463, CAB069396" Approved "CAB004463: AB_675868, CAB069396: AB_1619977" "unprognostic (7.49e-2)" "unprognostic (1.47e-1)" "unprognostic (2.74e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-2)" "unprognostic (1.60e-2)" "prognostic unfavourable (8.66e-4)" "unprognostic (4.23e-2)" "unprognostic (5.98e-2)" "unprognostic (4.31e-3)" "unprognostic (2.33e-1)" "unprognostic (6.06e-2)" "prognostic favourable (8.66e-4)" "unprognostic (1.58e-1)" "unprognostic (9.95e-2)" "unprognostic (1.85e-2)" "unprognostic (1.01e-3)" 13.4 11.7 15.3 11.5 18.5 13.3 22.1 33.6 35.2 15.2 13.9 12.9 19.5 16.7 17.1 10.8 16.1 12.4 15.1 11.2 20.0 18.0 20.1 23.6 11.7 12.0 15.9 16.7 18.9 15.3 12.7 23.7 12.2 23.6 13.0 14.3 12.4 17.2 15.9 18.9 10.8 17.7 14.6 13.7 9.6 12.2 23.4 12.2 20.5 22.3 9.0 13.8 11.8 13.0 4.5 4.3 5.2 4.3 4.7 5.7 3.5 15.7 4.3 14.3 8.1 5.5 6.5 11.1 23.8 16.3 14.3 11.7 4.9 16.4 5.7 6.5 13.3 9.7 5.0 9.2 18.7 34.1 8.2 8.2 5.0 6.7 9.1 14.0 9.6 5.5 10.6 10.6 21.1 13.1 13.1 10.6 9.3 4.6 17.1 7.4 8.9 3.1 11.2 14.7 5.7 8.7 6.1 24.1 19.1 9.3 7.8 10.7 8.5 6.7 11.2 10.7 25.6 8.1 17.9 3.3 8.1 11.6 7.4 14.9 6.1 0.0 3.3 3.0 4.1 2.8 4.7 4.5 5.7 5.0 3.3 2.9 5.6 3.9 5.2 4.7 4.3 4.3 2.9 3.5 15.3 18.5 33.6 35.2 20.0 18.0 15.9 16.7 23.6 12.2 MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.7" "Cell line enhanced" "Detected in all" "HDLM-2: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "basophil: 13.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008910 Approved "CAB008910: " "unprognostic (5.04e-3)" "unprognostic (2.06e-2)" "prognostic favourable (1.11e-4)" "unprognostic (8.53e-2)" "unprognostic (1.75e-1)" "unprognostic (5.06e-3)" "unprognostic (6.83e-3)" "unprognostic (3.16e-1)" "unprognostic (4.93e-2)" "unprognostic (3.76e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (9.38e-3)" "unprognostic (2.40e-1)" 10.3 12.4 22.9 9.6 31.8 10.3 11.4 48.7 41.4 10.8 12.4 10.6 4.7 10.1 8.7 9.5 8.7 8.8 7.8 14.0 24.3 25.0 12.2 9.7 10.8 10.0 22.0 21.0 8.5 25.9 16.3 8.8 10.9 29.4 11.7 15.3 7.0 9.9 13.1 20.5 6.3 10.4 11.4 16.8 8.6 12.3 9.4 10.3 7.1 15.4 5.1 11.3 9.9 7.3 1.4 1.4 13.2 2.4 1.3 3.1 0.3 17.0 14.1 12.5 15.6 12.4 13.9 26.9 16.4 14.6 13.9 13.9 18.5 12.2 18.3 28.4 17.4 13.1 12.8 27.6 16.3 68.7 12.4 7.6 15.7 13.1 9.4 15.7 13.3 10.2 12.4 13.4 13.0 16.4 8.4 13.3 18.8 22.4 15.6 6.6 8.7 8.4 15.2 21.3 8.7 10.5 16.4 14.4 10.2 19.3 18.8 13.1 19.1 13.7 11.7 16.6 16.8 23.4 24.5 9.6 11.3 12.5 17.6 14.7 11.0 13.2 0.6 2.5 2.0 1.3 2.0 1.0 1.5 1.8 1.0 1.4 1.0 1.2 0.9 1.3 2.4 1.4 3.1 0.3 22.9 31.8 48.7 41.4 24.3 25.0 22.0 21.0 29.4 10.3 MAPKAPK2 ENSG00000162889 "Mitogen-activated protein kinase-activated protein kinase 2" P49137 1 206684944-206734283 "Cancer-related genes, Enzymes, Predicted membrane proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in all" 6 "dendritic cells: 18.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010297, HPA045556, HPA063708, HPA064435" Approved Supported Nucleoplasm,Centrosome Nucleoplasm Centrosome "CAB010297: AB_2250405, HPA045556: , HPA063708: , HPA064435: " "unprognostic (7.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-2)" "prognostic unfavourable (1.93e-4)" "unprognostic (9.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "prognostic unfavourable (4.58e-6)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (6.96e-2)" "unprognostic (3.29e-2)" 23.0 25.3 11.6 21.2 15.7 58.6 23.9 11.1 14.5 19.3 25.6 17.2 14.5 25.7 20.0 18.5 23.5 17.3 26.0 89.2 12.3 8.7 33.7 26.7 26.7 21.5 16.7 6.5 23.3 19.1 16.9 22.8 13.6 15.7 20.2 14.4 17.8 19.8 14.4 62.9 18.3 32.9 18.3 14.6 37.7 23.1 21.3 14.6 26.9 24.3 25.2 28.2 22.9 46.1 1.1 18.7 3.2 1.1 2.3 1.6 0.5 20.9 8.3 11.5 12.9 34.0 20.0 14.3 14.6 33.1 22.3 21.1 15.8 10.2 10.1 10.2 29.4 15.9 8.6 15.5 16.1 11.7 6.5 16.9 10.3 10.2 26.3 24.9 56.6 27.5 19.9 21.4 23.7 18.2 19.4 45.9 18.0 26.0 10.0 18.0 13.3 11.6 25.8 24.1 3.2 16.8 12.8 9.2 11.9 17.2 29.1 20.2 14.1 24.2 17.3 20.1 17.0 23.3 19.8 59.8 53.1 8.2 22.8 15.2 6.6 1.1 0.7 1.4 1.6 1.1 1.5 1.0 1.2 1.5 0.6 1.1 0.6 1.1 3.2 2.3 1.0 18.7 1.4 0.5 11.6 15.7 11.1 14.5 12.3 8.7 16.7 6.5 15.7 14.6 MAPKAPK3 "3pK, MAPKAP3" ENSG00000114738 "Mitogen-activated protein kinase-activated protein kinase 3" Q16644 3 50611520-50649297 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 86.7;skeletal muscle: 70.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 30.2;eosinophil: 23.0;intermediate monocyte: 50.0;myeloid DC: 27.1;neutrophil: 20.5;non-classical monocyte: 61.4;plasmacytoid DC: 16.9" "Group enriched" "Detected in all" 5 "dendritic cells: 27.1;granulocytes: 23.0;monocytes: 61.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm Nucleoplasm "HPA058275: " "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favourable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favourable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" 8.9 16.1 5.6 9.3 7.2 30.4 6.3 1.9 6.2 5.5 9.5 7.1 7.5 9.9 5.5 8.6 16.8 5.1 8.5 86.7 4.8 3.7 17.9 11.9 11.0 15.1 7.2 4.1 8.7 24.2 11.2 9.0 9.0 6.0 7.6 6.7 10.9 12.4 9.2 70.1 17.6 12.0 5.2 5.9 12.5 9.0 4.0 5.2 25.9 22.6 40.9 14.3 6.1 7.5 3.0 27.1 23.0 61.4 7.3 6.4 19.5 23.0 7.1 3.0 8.5 4.6 11.5 6.7 5.6 8.0 8.7 7.4 11.1 21.5 9.3 5.7 18.7 8.2 20.5 22.1 7.8 20.4 4.9 48.7 10.2 10.1 9.1 35.0 25.9 9.1 13.8 20.2 27.5 7.6 13.6 6.1 18.2 9.4 14.9 35.3 11.2 29.5 6.6 7.2 13.9 40.3 13.2 5.6 4.0 5.0 14.2 6.4 8.9 21.7 5.5 6.8 15.7 35.3 13.8 4.1 7.6 7.7 36.4 55.1 2.8 6.4 30.2 23.0 5.5 50.0 5.4 3.0 6.2 6.4 27.1 1.8 4.9 5.5 20.5 7.3 61.4 16.9 5.2 19.5 5.6 7.2 1.9 6.2 4.8 3.7 7.2 4.1 6.0 5.2 MAPKAPK5 PRAK ENSG00000089022 "Mitogen-activated protein kinase-activated protein kinase 5" Q8IW41 12 111841978-111902238 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB004546: AB_627910, HPA015515: AB_1853569" "unprognostic (6.45e-2)" "unprognostic (7.29e-2)" "unprognostic (1.27e-3)" "unprognostic (1.09e-2)" "unprognostic (5.52e-2)" "unprognostic (3.76e-2)" "prognostic unfavourable (2.98e-8)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (3.20e-1)" "unprognostic (6.03e-2)" "unprognostic (3.39e-2)" "unprognostic (9.41e-2)" "unprognostic (3.25e-2)" 20.7 26.2 21.4 17.5 26.4 24.1 21.7 23.7 28.3 17.3 28.8 26.1 21.9 26.3 25.8 22.8 20.8 17.5 22.7 20.7 17.7 15.2 21.7 21.5 18.9 19.4 22.3 20.4 21.3 24.5 19.8 20.4 21.0 17.3 18.7 32.9 23.6 23.3 20.5 33.2 23.0 28.4 21.1 18.0 18.4 19.8 16.7 22.0 19.3 20.5 15.1 19.3 19.9 16.5 4.9 4.1 3.2 11.4 3.9 6.8 2.5 15.1 20.2 19.5 16.4 14.1 14.3 29.7 15.2 18.4 23.4 16.2 26.0 12.5 22.9 11.3 17.9 15.2 25.6 15.9 22.0 15.2 14.0 20.4 14.0 20.8 17.1 25.6 14.5 15.1 22.9 22.3 26.6 17.1 28.1 9.1 17.0 17.0 25.4 40.5 27.7 14.2 25.2 14.2 22.0 18.6 22.0 24.1 20.4 17.3 29.5 21.1 23.8 29.3 14.9 13.3 13.4 13.6 19.0 18.6 22.7 27.1 16.2 18.7 18.8 1.3 4.8 3.2 6.5 3.5 3.5 4.9 4.3 4.7 3.3 4.0 6.8 5.1 2.5 3.9 11.4 4.1 6.6 2.5 21.4 26.4 23.7 28.3 17.7 15.2 22.3 20.4 17.3 22.0 MARCH1 "FLJ20668, MARCH-I, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.4;lymphoid tissue: 32.4" "Cell line enhanced" "Detected in many" "Daudi: 9.4;U-266/70: 9.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 95 "classical monocyte: 16.8;eosinophil: 9.9;intermediate monocyte: 17.0;memory B-cell: 18.5;myeloid DC: 18.1;naive B-cell: 15.7;non-classical monocyte: 17.2;plasmacytoid DC: 6.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014600 Uncertain Supported Mitochondria Mitochondria "HPA014600: AB_1853573" "unprognostic (7.29e-2)" "unprognostic (5.82e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" "unprognostic (8.25e-2)" "unprognostic (2.98e-2)" "unprognostic (4.79e-3)" "unprognostic (9.00e-2)" "unprognostic (3.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (1.24e-1)" "unprognostic (7.00e-2)" "unprognostic (2.48e-2)" "unprognostic (2.70e-1)" "unprognostic (2.91e-2)" 7.7 4.2 11.6 20.5 19.7 3.9 4.0 3.1 14.5 3.7 3.9 8.5 0.1 4.4 3.9 4.6 3.6 4.2 5.9 2.6 12.6 10.1 3.0 4.5 8.3 28.5 17.3 6.3 4.2 4.1 1.5 4.1 10.2 13.5 3.5 5.1 2.4 4.6 1.8 1.6 4.9 9.0 6.5 24.4 32.4 4.1 2.3 17.9 2.6 3.2 1.4 24.6 9.0 4.2 18.5 18.1 9.9 17.2 0.1 0.0 6.6 0.8 0.7 2.9 1.7 0.0 0.0 1.8 1.2 0.1 0.0 0.0 1.6 3.3 9.4 3.5 0.0 1.4 0.0 0.0 0.0 1.0 1.0 6.7 3.7 0.6 0.0 4.1 2.2 0.0 0.0 0.0 0.2 0.0 2.5 4.9 3.3 1.0 2.3 2.6 3.6 1.3 2.6 0.5 0.7 0.1 1.5 1.5 1.3 0.9 1.4 0.5 4.0 0.7 3.1 1.1 2.0 0.7 2.3 9.7 3.2 2.6 1.3 2.1 1.5 0.0 16.8 9.9 0.0 17.0 0.0 18.5 0.0 0.0 18.1 15.7 0.0 0.0 0.1 0.1 17.2 6.8 0.0 6.6 11.6 19.7 3.1 12.5 12.6 10.1 17.3 6.3 13.5 17.9 MARCH10 "FLJ35757, MARCH-X, RNF190" ENSG00000173838 "Membrane associated ring-CH-type finger 10" Q8NA82 17 62701314-62808344 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 80.2" "Cell line enhanced" "Detected in some" "BEWO: 3.8;EFO-21: 7.2;HSkMC: 3.2;SCLC-21H: 12.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "gdT-cell: 3.4" "Lineage enriched" "Detected in single" 5 "T-cells: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA023322 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA023322: AB_1856351" "unprognostic (2.79e-2)" "unprognostic (2.32e-1)" "unprognostic (9.60e-3)" "unprognostic (6.95e-2)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-2)" "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (7.99e-4)" "unprognostic (3.16e-1)" "unprognostic (2.85e-3)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (9.37e-3)" "unprognostic (2.66e-1)" 0.2 0.1 0.7 0.2 1.6 0.0 0.1 0.1 0.3 0.5 0.1 1.9 0.6 0.0 0.3 4.8 0.1 7.9 0.1 0.1 1.0 1.0 0.6 0.1 1.4 0.1 0.2 0.5 1.0 0.1 0.3 4.5 0.1 1.8 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 80.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.7 0.0 0.0 0.6 3.4 0.3 0.1 0.0 0.2 0.0 0.0 0.2 3.8 1.6 0.2 1.2 0.3 0.0 0.1 0.0 7.2 0.5 0.0 0.0 0.4 1.3 0.0 0.0 1.2 0.7 0.0 1.5 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.4 0.1 0.1 0.3 0.2 0.0 0.0 0.2 1.1 0.0 12.4 0.0 0.0 0.7 0.1 0.2 0.0 0.0 0.0 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 3.4 0.0 1.5 0.0 0.7 0.3 0.7 0.1 0.6 1.8 0.0 0.6 0.0 0.0 0.7 0.3 0.7 1.6 0.1 0.3 1.0 1.0 0.2 0.5 1.8 0.3 MARCH2 "HSPC240, MARCH-II, RNF172" ENSG00000099785 "Membrane associated ring-CH-type finger 2" Q9P0N8 19 8413270-8439017 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014063 Approved Supported "Endoplasmic reticulum,Cytosol" "Endoplasmic reticulum" Cytosol "HPA014063: AB_1853576" "unprognostic (1.15e-2)" "unprognostic (4.01e-3)" "prognostic unfavourable (6.48e-4)" "prognostic favourable (1.05e-5)" "unprognostic (3.00e-1)" "prognostic favourable (8.29e-4)" "unprognostic (3.43e-2)" "unprognostic (6.95e-2)" "unprognostic (3.06e-3)" "unprognostic (2.32e-1)" "prognostic favourable (6.21e-4)" "unprognostic (2.01e-1)" "unprognostic (3.52e-1)" "unprognostic (1.01e-1)" "unprognostic (3.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.80e-2)" 37.7 12.4 30.7 13.5 28.3 17.5 23.9 8.6 39.1 9.8 29.8 20.7 9.7 11.2 12.5 39.0 19.3 10.0 11.4 38.9 23.5 21.9 11.0 17.9 18.2 15.0 30.8 19.8 8.2 10.0 10.5 11.3 13.9 20.2 16.0 10.3 12.7 13.4 21.8 46.9 12.7 11.7 28.5 27.8 18.9 13.3 8.6 13.3 8.4 21.3 14.1 10.0 20.4 9.7 3.6 26.5 20.4 14.6 3.7 7.3 10.1 5.4 7.0 3.2 14.7 19.5 6.4 5.4 6.0 7.3 4.8 5.0 3.4 2.6 2.2 17.6 12.8 3.9 4.1 8.4 3.7 10.9 9.7 16.7 3.3 7.6 10.5 2.4 25.1 7.6 9.7 4.6 4.1 18.7 2.3 12.3 3.7 10.5 3.3 7.9 6.6 17.0 5.3 1.0 5.5 11.0 6.5 1.6 8.9 0.4 6.4 11.3 4.9 5.2 18.8 6.7 4.1 22.3 5.0 11.0 13.0 2.5 10.9 5.0 5.1 20.4 10.0 15.4 5.7 14.6 5.9 3.6 5.9 4.6 6.7 3.5 4.0 5.4 12.5 3.7 12.8 26.5 7.3 10.1 30.7 28.3 8.6 39.1 23.5 21.9 30.8 19.8 20.2 13.3 MARCH3 "MARCH-III, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030808 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 24.6;HUVEC TERT2: 16.4;TIME: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 8.8;naive B-cell: 13.1" "Lineage enriched" "Detected in many" 5 "B-cells: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043406 Uncertain Supported Vesicles Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 11.3 6.0 5.6 11.0 9.4 6.6 6.2 5.3 4.8 2.0 10.8 8.2 0.5 2.4 3.7 3.6 3.4 3.2 10.4 15.2 7.8 6.8 2.0 1.9 5.2 5.2 9.5 2.3 4.0 5.0 1.7 10.8 4.0 12.3 2.9 11.8 9.7 11.2 1.1 11.9 11.5 5.2 6.5 16.0 3.7 5.5 14.2 7.6 2.1 3.6 3.4 5.8 6.5 6.7 13.1 0.7 2.5 0.4 1.9 2.6 0.7 0.3 1.2 2.3 1.2 2.1 2.0 0.7 8.4 3.5 6.8 10.0 1.1 0.5 2.2 0.8 1.3 0.7 2.9 1.5 9.6 0.5 2.7 7.0 1.9 1.1 3.4 2.8 1.8 1.4 0.5 24.6 2.9 16.4 2.9 0.4 5.5 0.8 0.3 1.2 2.0 2.8 0.9 9.4 0.6 0.5 1.2 0.7 0.5 1.9 0.3 1.0 1.7 2.9 19.9 1.3 1.0 7.7 0.9 1.1 1.3 1.3 5.0 2.3 1.1 0.0 0.2 2.5 0.5 0.4 0.1 8.8 0.6 0.3 0.1 13.1 2.4 0.5 0.8 1.9 0.3 0.7 2.6 0.7 5.6 9.4 5.3 4.8 7.8 6.8 9.5 2.3 12.3 7.6 MARCH4 "KIAA1399, MARCH-IV, RNF174" ENSG00000144583 "Membrane associated ring-CH-type finger 4" Q9P2E8 2 216257865-216372027 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 16.6;pituitary gland: 13.1" "Cell line enhanced" "Detected in many" "BJ: 33.3;fHDF/TERT166: 21.2;TIME: 15.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014348 Approved "HPA014348: AB_1853578" "unprognostic (4.84e-2)" "unprognostic (1.02e-4)" "unprognostic (1.63e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (6.49e-2)" "unprognostic (5.55e-3)" "unprognostic (1.07e-1)" "unprognostic (6.81e-5)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.09e-3)" 0.7 2.9 7.0 0.7 11.9 0.7 0.6 1.0 16.6 0.6 1.1 0.3 0.0 1.5 0.7 0.7 0.6 2.5 0.6 0.6 5.8 5.6 0.6 0.6 0.8 0.6 2.0 4.8 0.6 1.5 0.6 13.1 3.1 3.4 0.7 1.2 0.1 0.6 0.6 0.6 0.7 1.4 0.6 1.6 0.6 5.1 0.7 1.1 0.0 0.6 0.0 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.5 1.2 0.0 0.0 0.1 0.8 0.0 33.3 11.4 7.2 2.5 0.0 0.5 0.0 5.2 21.2 0.0 0.0 13.1 7.1 0.0 0.0 2.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 6.5 9.9 9.3 0.0 0.0 11.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.9 0.0 0.0 0.0 0.0 0.0 15.6 11.2 11.6 0.0 8.9 0.0 0.0 0.0 2.5 0.0 7.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 7.0 11.9 1.0 16.6 5.8 5.6 2.0 4.8 3.4 1.1 MARCH5 "FLJ20445, MARCH-V, MITOL, RNF153" ENSG00000198060 "Membrane associated ring-CH-type finger 5" Q9NX47 10 92291163-92353964 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056596 Supported Mitochondria Mitochondria "HPA056596: " "unprognostic (4.00e-2)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (4.10e-2)" "unprognostic (5.47e-3)" "unprognostic (2.33e-3)" "unprognostic (4.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.24e-2)" "unprognostic (9.77e-2)" "unprognostic (5.50e-3)" "unprognostic (4.02e-3)" "unprognostic (6.14e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (4.53e-1)" "unprognostic (2.85e-2)" 18.2 21.7 17.5 17.7 18.3 20.7 27.1 16.8 25.7 15.5 15.4 12.7 20.7 15.8 19.3 18.8 28.0 14.8 15.4 18.4 15.8 15.1 21.7 27.6 16.5 16.6 16.3 17.9 20.9 16.7 16.3 12.3 16.3 14.8 22.2 14.8 14.5 19.4 19.3 42.6 13.7 16.0 18.1 14.0 12.1 14.4 20.1 13.5 25.0 24.5 21.5 17.3 14.7 21.0 7.3 9.4 16.8 10.2 6.5 8.7 6.6 16.4 8.9 17.6 20.2 12.1 12.6 9.1 14.7 16.2 18.4 18.9 5.9 11.8 9.6 10.2 14.4 13.6 12.3 12.3 26.5 7.2 14.5 7.7 8.4 13.9 14.6 12.3 7.7 12.8 16.7 12.1 25.5 16.1 8.4 12.0 14.7 10.4 10.8 14.1 4.1 13.5 11.8 18.1 5.7 18.8 10.7 8.2 15.2 12.8 9.5 15.6 16.5 9.6 15.6 8.6 9.5 9.4 20.1 12.2 9.3 8.5 7.9 17.0 5.7 5.2 8.3 9.0 7.6 10.2 7.6 7.3 8.4 8.0 9.4 6.7 8.7 8.3 16.8 6.5 8.5 6.2 7.8 6.6 17.5 18.3 16.8 25.7 15.8 15.1 16.3 17.9 14.8 13.5 MARCH6 "MARCH-VI, RNF176, TEB4" ENSG00000145495 "Membrane associated ring-CH-type finger 6" O60337 5 10353703-10440388 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040841, HPA063246" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA040841: , HPA063246: " "unprognostic (3.31e-2)" "unprognostic (2.04e-1)" "unprognostic (2.85e-2)" "unprognostic (3.80e-3)" "unprognostic (4.00e-1)" "unprognostic (2.26e-1)" "unprognostic (3.06e-2)" "unprognostic (9.52e-3)" "unprognostic (1.53e-1)" "unprognostic (1.05e-3)" "unprognostic (3.94e-2)" "unprognostic (5.58e-2)" "unprognostic (5.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.88e-1)" "unprognostic (3.57e-1)" "unprognostic (8.50e-3)" 22.5 25.6 28.6 21.2 25.5 57.0 62.4 42.0 53.8 21.4 23.0 24.0 18.3 28.6 24.7 24.2 22.8 25.1 22.0 35.5 27.6 23.7 31.9 28.9 35.0 33.2 29.8 39.1 34.0 41.5 56.0 27.4 20.3 33.4 21.4 18.4 20.3 28.0 23.4 49.8 23.9 32.1 27.4 38.6 31.2 26.0 25.6 26.9 18.0 26.8 17.1 20.3 24.6 36.4 13.4 7.3 15.6 12.1 9.9 15.7 9.4 12.4 18.7 31.4 24.3 18.0 14.5 25.7 19.7 18.4 17.0 21.8 17.8 33.3 13.1 30.1 18.4 17.3 16.6 12.8 23.1 27.7 15.1 17.1 62.2 12.1 12.7 20.2 19.2 16.9 14.2 17.1 18.7 15.8 20.4 29.6 15.5 14.2 10.9 15.6 11.4 13.2 17.0 13.1 18.9 13.3 24.2 13.5 19.6 36.7 20.1 12.9 16.7 11.0 15.2 20.7 20.2 10.2 14.7 20.8 29.8 18.7 15.2 14.1 14.7 15.6 8.5 13.6 13.5 9.6 15.4 13.4 13.4 13.4 7.3 11.5 15.7 14.6 13.7 9.9 12.1 5.6 11.7 9.4 28.6 25.5 42.0 53.8 27.6 23.7 29.8 39.1 33.4 26.9 MARCH7 "AXOT, MARCH-VII, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014275, HPA022152" Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA014275: AB_10599820, HPA022152: AB_10601107" "unprognostic (2.42e-1)" "unprognostic (2.24e-1)" "unprognostic (1.02e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (2.10e-1)" "prognostic unfavourable (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (3.17e-2)" "unprognostic (3.53e-2)" "prognostic unfavourable (1.84e-4)" "unprognostic (1.41e-3)" "unprognostic (1.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" 31.6 21.1 18.3 27.4 29.0 22.6 28.9 33.1 23.0 33.4 25.3 17.0 22.0 17.1 32.3 24.1 47.6 22.7 22.4 28.1 16.9 14.4 21.8 30.9 29.5 32.9 21.6 17.8 31.6 15.4 25.3 31.5 41.3 21.5 28.8 22.3 24.8 25.7 22.6 48.0 24.2 25.2 33.8 20.4 28.9 20.0 34.1 21.8 60.4 28.5 25.5 32.9 30.0 35.1 10.0 10.1 46.1 14.5 14.0 14.6 10.5 18.5 12.8 34.5 15.5 25.0 33.1 33.4 31.2 31.6 32.1 29.5 26.4 22.3 26.4 14.2 32.5 23.5 21.2 28.8 41.2 27.0 15.6 35.8 18.6 19.9 24.3 29.3 28.0 29.4 32.9 39.2 34.0 38.5 27.2 25.5 32.4 15.2 18.7 28.1 32.5 18.4 27.9 25.5 21.9 29.5 38.7 20.5 19.3 25.5 18.8 25.0 21.8 35.6 34.7 34.4 20.8 21.1 17.6 20.4 21.4 36.0 21.3 17.8 32.0 24.8 10.3 20.6 11.1 10.6 13.3 10.0 12.1 12.6 10.1 9.7 14.6 14.1 46.1 14.0 14.5 7.9 12.5 10.5 18.3 29.0 33.1 23.0 16.9 14.4 21.6 17.8 21.5 21.8 MARCH8 "c-MIR, CMIR, MARCH-VIII, MIR, RNF178" ENSG00000165406 "Membrane associated ring-CH-type finger 8" Q5T0T0 10 45454585-45594906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014597 Approved "HPA014597: AB_1853580" "unprognostic (1.38e-1)" "unprognostic (3.69e-2)" "unprognostic (1.74e-1)" "unprognostic (1.68e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (3.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (2.04e-1)" "prognostic favourable (2.71e-4)" "unprognostic (1.28e-1)" "prognostic favourable (6.64e-4)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.85e-1)" "unprognostic (3.12e-2)" 10.0 17.6 13.5 11.4 16.0 28.8 12.1 37.5 12.2 10.3 14.6 24.5 8.5 9.7 14.3 8.2 7.5 11.1 9.9 14.1 12.7 11.8 11.0 16.7 10.3 13.5 19.0 9.3 14.2 18.2 15.1 18.1 13.2 14.5 8.8 12.9 12.9 11.5 11.4 9.0 8.9 18.8 12.4 18.2 14.3 9.7 43.2 14.9 10.5 11.5 8.5 13.6 11.0 8.0 5.3 1.7 13.6 1.8 7.3 4.7 2.4 9.1 9.2 7.9 7.0 11.5 14.4 5.9 4.2 19.8 7.8 8.6 2.3 9.5 13.2 7.3 12.3 1.7 8.6 7.2 7.3 20.0 9.5 5.1 4.2 5.5 8.0 6.1 22.7 11.7 9.3 4.0 10.5 12.8 14.3 13.0 6.0 3.2 6.2 3.9 2.6 3.0 7.0 7.9 3.8 5.9 5.3 7.0 9.8 8.3 2.0 7.9 12.2 2.9 8.7 6.2 8.0 9.0 6.6 23.0 18.4 5.8 12.2 8.6 1.6 9.7 1.1 10.0 3.1 1.8 4.7 3.5 3.4 3.3 1.6 5.3 2.7 3.3 13.6 7.3 0.9 1.7 3.1 2.4 13.5 16.0 37.5 12.2 12.7 11.8 19.0 9.3 14.5 14.9 MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528183-220664461 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 9.4;RT4: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain "HPA007421: AB_1079311, HPA008061: AB_1079310" "unprognostic (1.51e-1)" "unprognostic (6.27e-2)" "unprognostic (6.72e-2)" "unprognostic (3.63e-2)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-2)" "unprognostic (3.48e-1)" "prognostic unfavourable (2.63e-4)" "unprognostic (4.59e-2)" "prognostic favourable (2.23e-5)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (9.56e-3)" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" 14.3 5.6 11.4 4.6 13.5 0.9 9.0 15.2 22.7 9.8 6.7 4.7 6.4 2.1 7.8 26.6 9.4 5.9 5.0 19.1 10.0 12.5 4.7 1.5 4.8 2.3 10.3 12.4 3.7 3.0 5.8 12.1 3.9 13.2 7.2 4.1 6.2 5.0 11.3 4.2 3.5 3.4 10.1 7.1 3.2 4.3 16.0 4.6 0.4 8.4 5.3 5.7 8.8 14.9 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 4.5 1.2 0.0 0.0 1.8 1.5 2.2 1.5 2.3 0.0 0.0 0.0 0.0 0.0 2.3 9.4 6.1 1.1 0.0 6.9 0.0 2.4 0.0 0.0 0.7 0.9 0.7 5.2 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.7 2.2 0.0 7.0 0.0 0.0 35.3 6.5 5.8 0.3 0.3 0.4 0.7 0.0 0.0 0.0 3.5 4.8 6.1 0.0 0.0 0.0 1.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.4 13.5 15.2 17.5 10.0 12.5 10.3 12.4 13.2 4.6 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911019 "Enzymes, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: " "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavourable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavourable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 9.7 11.6 16.5 16.3 21.4 18.5 13.8 24.7 26.1 15.2 20.5 20.0 11.1 21.3 13.6 7.5 48.4 13.6 14.4 14.7 17.0 10.1 11.9 12.4 15.4 16.3 18.1 13.7 11.0 17.3 21.8 22.4 21.1 15.0 14.9 19.8 10.6 20.7 14.3 15.7 35.8 26.9 13.3 13.3 21.6 16.8 9.8 18.7 22.9 15.9 13.6 23.5 14.8 21.3 2.9 1.9 9.8 1.9 3.3 4.5 1.2 22.4 15.0 12.3 12.9 6.7 8.9 17.1 9.1 8.8 13.2 10.2 16.1 23.7 16.6 16.2 9.5 29.0 11.8 14.3 11.5 11.4 9.3 18.2 11.8 10.4 7.6 19.8 24.1 4.9 19.5 12.1 10.5 10.8 15.5 19.1 8.7 27.6 20.7 14.1 14.0 10.9 17.1 9.1 18.3 9.8 18.6 17.0 11.4 15.8 40.4 10.6 29.4 11.8 10.3 14.0 8.8 18.0 10.1 11.6 12.0 16.2 9.5 10.4 11.1 2.7 1.7 4.4 2.9 1.5 4.5 2.3 3.2 3.1 1.9 2.9 2.6 2.4 9.8 3.3 1.9 1.7 1.5 1.2 16.5 21.4 24.7 26.1 17.0 10.1 18.1 13.7 15.0 18.7 MARK3 "CTAK1, KP78, PAR-1A" ENSG00000075413 "Microtubule affinity regulating kinase 3" P27448 14 103385392-103503831 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 14 "eosinophil: 42.2" "Lineage enriched" "Detected in many" 23 "granulocytes: 42.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024652 Approved "HPA024652: AB_1853582" "unprognostic (6.86e-2)" "unprognostic (2.93e-1)" "unprognostic (7.70e-2)" "unprognostic (3.48e-2)" "unprognostic (8.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-3)" "unprognostic (2.21e-1)" "prognostic unfavourable (1.14e-4)" "unprognostic (2.29e-3)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (1.60e-1)" 20.8 31.9 24.6 20.9 29.5 62.7 19.7 59.1 30.2 25.3 20.8 33.2 19.9 17.4 28.5 28.4 24.4 23.1 22.2 33.6 24.9 22.4 20.3 20.1 25.9 20.8 29.6 23.3 24.6 30.7 28.1 30.9 20.5 27.4 19.3 20.0 23.6 18.3 23.1 40.9 19.9 19.2 26.8 20.9 26.8 26.9 24.1 30.3 29.1 25.8 23.1 23.0 20.8 29.0 1.2 1.2 42.2 1.1 0.8 1.8 0.4 13.2 16.1 23.5 17.7 28.2 22.1 20.3 23.6 24.9 28.6 27.5 12.6 20.9 15.8 15.0 22.1 25.0 25.6 25.4 36.4 18.4 11.3 20.4 17.1 15.8 53.2 23.3 13.6 25.6 23.6 23.1 47.4 26.4 21.0 37.0 21.4 35.6 15.9 20.7 17.2 24.3 20.9 24.0 12.7 25.3 28.3 20.7 20.6 25.0 17.2 22.9 23.4 20.0 22.8 15.4 10.9 28.6 21.0 24.0 30.4 19.0 18.7 18.7 20.7 0.4 1.1 42.2 1.1 0.8 0.9 1.2 1.6 1.8 1.1 0.9 1.8 1.4 3.1 0.8 0.7 1.2 1.6 0.4 24.6 29.5 59.1 30.2 24.9 22.4 29.6 23.3 27.4 30.3 MARK4 "FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D" ENSG00000007047 "Microtubule affinity regulating kinase 4" Q96L34 19 45079288-45305283 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039186 Approved Supported Cytosol Cytosol "HPA039186: AB_10796223" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.57e-3)" "prognostic unfavourable (8.31e-8)" "unprognostic (2.02e-1)" "prognostic unfavourable (3.05e-5)" "unprognostic (1.90e-1)" "unprognostic (2.16e-2)" "unprognostic (6.26e-2)" "unprognostic (5.64e-3)" "unprognostic (1.24e-3)" "unprognostic (7.50e-2)" "unprognostic (3.80e-2)" "unprognostic (6.89e-2)" "unprognostic (7.23e-2)" "unprognostic (4.65e-2)" "unprognostic (3.02e-2)" 11.8 13.0 19.4 10.3 26.0 8.4 15.2 21.9 28.6 11.4 10.2 9.0 12.9 6.6 14.0 17.5 13.5 12.9 13.4 14.7 22.2 15.7 8.7 13.5 11.7 10.5 14.3 21.6 21.0 16.8 13.7 12.9 12.1 15.0 12.2 6.3 14.1 12.1 14.2 40.7 20.6 7.5 14.1 10.8 12.4 10.3 32.1 12.3 11.2 10.5 11.5 9.4 13.7 17.9 1.0 2.8 3.5 2.9 1.8 4.3 1.2 8.8 3.8 15.0 10.9 10.7 17.1 4.2 6.6 10.3 9.8 9.2 2.3 5.1 4.3 5.6 12.0 6.0 10.6 9.6 5.5 7.8 8.7 8.5 4.6 8.2 19.7 2.1 7.4 21.2 13.7 8.2 9.5 13.1 10.8 10.7 10.6 7.4 7.5 6.7 6.4 3.3 29.3 4.9 2.8 9.3 7.2 28.1 12.4 9.7 8.6 5.0 4.1 12.4 10.6 8.8 6.7 6.0 4.2 12.0 9.5 4.8 9.4 4.0 7.0 3.5 2.9 0.7 3.4 2.2 0.7 0.9 1.2 4.3 0.8 1.0 2.3 2.6 2.9 1.8 2.0 2.8 2.4 1.2 19.4 26.0 21.9 22.7 22.2 15.7 14.3 21.6 15.0 12.3 MARS "CMT2U, MetRS, SPG70" ENSG00000166986 "Methionyl-tRNA synthetase" P56192 12 57475445-57517569 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004125, CAB017097" Supported Approved Enhanced Cytosol 21000 Cytosol "CAB017097: , HPA004125: AB_1079312" "prognostic unfavourable (1.73e-4)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.57e-2)" "unprognostic (4.90e-3)" "prognostic unfavourable (4.55e-7)" "unprognostic (8.47e-2)" "unprognostic (1.73e-1)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (3.77e-2)" "prognostic unfavourable (1.59e-4)" "unprognostic (1.13e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (2.06e-2)" 23.8 26.7 35.1 27.3 29.1 23.0 19.8 25.1 36.0 17.4 23.9 23.1 23.9 17.3 23.3 36.3 29.5 17.9 16.1 25.0 28.0 29.5 20.5 45.9 24.3 25.1 40.1 25.5 25.8 48.3 35.7 34.0 22.2 30.9 25.6 24.7 19.8 26.0 30.0 24.5 18.4 20.1 33.7 30.7 30.7 31.3 29.6 30.9 21.4 26.9 22.3 34.3 24.3 27.9 12.9 29.3 19.0 27.0 14.1 18.9 15.5 16.5 23.0 15.4 26.7 17.3 10.5 28.4 23.7 27.8 25.1 26.9 24.7 18.4 29.1 15.7 28.7 18.8 35.1 30.6 26.3 25.2 15.2 20.5 8.6 13.9 38.5 30.9 23.6 15.3 47.6 28.7 74.4 17.9 31.7 62.4 17.4 22.9 27.6 23.3 29.1 25.4 24.0 116.3 30.1 18.9 13.0 20.6 20.9 12.3 18.9 32.8 25.0 40.5 13.2 9.1 26.9 13.1 14.0 57.2 57.8 35.1 22.3 23.5 31.0 12.1 14.6 19.0 18.9 27.0 17.2 12.9 12.9 17.1 29.3 7.7 11.1 15.2 7.2 14.1 21.8 28.4 13.1 15.5 35.1 29.1 25.1 36.0 28.0 29.5 40.1 25.5 30.9 30.9 MARS2 "mtMetRS, SPAX3" ENSG00000247626 "Methionyl-tRNA synthetase 2, mitochondrial" Q96GW9 2 197705369-197708387 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease mutation, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035589, HPA035590" Uncertain "HPA035589: AB_10601870, HPA035590: " "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-2)" "prognostic unfavourable (3.50e-4)" "prognostic favourable (1.12e-4)" "unprognostic (2.99e-2)" "unprognostic (2.35e-2)" "unprognostic (1.53e-1)" "unprognostic (7.61e-2)" "unprognostic (1.04e-1)" "unprognostic (9.54e-2)" "unprognostic (1.86e-3)" "prognostic favourable (6.14e-5)" "unprognostic (1.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.47e-2)" "unprognostic (8.74e-2)" 5.9 12.1 5.8 8.4 11.4 6.0 9.9 9.6 10.6 3.8 10.0 6.9 3.3 8.9 5.3 3.0 12.3 4.9 5.1 7.7 7.8 5.0 7.9 14.1 4.9 12.1 17.8 5.5 4.0 14.6 6.7 3.4 5.0 9.3 4.5 9.9 3.2 11.4 6.0 12.1 7.4 8.8 5.1 10.8 10.9 7.7 5.5 12.0 6.1 6.0 9.9 12.3 6.3 5.4 4.1 4.8 0.8 4.8 9.9 8.1 4.3 3.7 4.6 4.4 7.4 4.2 2.1 8.3 2.9 2.3 5.6 4.2 11.7 3.5 24.0 4.4 1.7 7.1 15.4 6.3 6.0 6.5 9.0 14.7 5.3 10.3 4.0 21.6 7.1 2.2 8.0 3.8 6.5 3.7 17.1 8.6 3.2 6.4 10.9 10.2 7.6 11.7 11.4 4.6 16.9 6.7 6.8 7.8 3.7 3.6 10.0 6.5 4.2 7.6 2.9 4.6 3.6 3.5 8.5 5.7 4.3 19.8 3.4 13.2 4.2 0.0 3.0 0.8 5.5 4.8 6.5 3.5 4.6 4.9 4.8 4.1 7.6 8.1 0.1 9.9 2.3 3.4 8.0 4.3 5.8 11.4 9.6 10.6 7.8 5.0 17.8 5.5 9.3 12.0 MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217285-187292022 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 43.4;liver: 80.1" "Group enriched" "Detected in some" 8 "BJ: 26.5;BJ hTERT+: 101.0" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" 8673000000 1800000000 "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favourable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" 2.1 1.4 3.6 1.2 3.8 0.1 1.2 1.9 10.2 43.4 19.1 14.8 2.4 0.8 34.9 7.1 4.1 6.7 3.3 39.6 6.1 2.5 1.6 80.1 2.2 0.4 6.4 3.0 1.7 0.2 0.2 0.5 3.2 13.0 17.4 2.1 0.1 0.9 19.4 12.2 2.5 2.6 17.1 21.8 0.4 0.6 1.5 6.7 0.0 1.3 6.3 3.5 4.4 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.7 0.0 26.5 101.0 0.3 0.1 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 3.8 1.9 3.5 6.1 2.5 6.4 3.0 13.0 6.7 MASP2 MASP1P1 ENSG00000009724 "Mannan binding lectin serine peptidase 2" O00187 1 11026523-11047233 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 98 "liver: 185.1" "Cell line enriched" "Detected in many" 7 "Hep G2: 20.1" "Cancer enriched" "Detected in some" 71 "liver cancer: 41.9" "Region enriched" "Detected in single" 4 "cerebellum: 1.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" 339700000 880000000 "Golgi apparatus" "HPA029313: AB_10669654, HPA029314: AB_10670029" "unprognostic (7.00e-2)" "unprognostic (8.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.89e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "prognostic favourable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (3.13e-2)" "unprognostic (4.04e-2)" "unprognostic (6.90e-3)" "unprognostic (8.30e-4)" "unprognostic (7.14e-2)" "unprognostic (3.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-4)" 0.3 0.2 0.3 0.4 0.3 1.8 0.3 1.7 0.5 0.3 0.3 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.1 0.3 185.1 0.3 0.6 0.3 0.3 0.5 0.4 0.0 0.3 0.3 0.3 0.3 0.0 0.3 0.7 0.3 1.4 1.4 0.5 0.3 0.3 0.6 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 1.4 1.2 1.2 0.2 0.8 1.3 0.0 0.5 0.3 2.9 1.6 0.0 0.1 0.4 0.8 0.0 0.0 0.0 1.3 1.1 2.3 0.6 0.0 0.7 0.0 0.0 0.0 0.6 2.3 1.4 2.5 20.1 0.0 2.1 1.6 0.0 0.0 0.1 0.0 0.0 0.8 0.5 0.0 0.6 0.6 1.1 0.4 0.6 1.8 1.0 0.5 0.0 1.4 1.8 0.7 0.9 0.5 0.5 0.6 1.3 1.1 0.9 0.6 1.0 0.6 0.7 1.1 1.7 0.6 1.9 0.4 1.2 0.2 1.1 0.7 0.1 1.0 0.7 0.9 0.8 0.5 1.4 1.3 1.3 0.2 0.8 0.2 1.2 0.1 0.0 0.3 0.3 1.7 0.3 0.3 0.1 0.3 0.3 0.3 0.3 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874951 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.0" "Cell line enhanced" "Detected in many" "AN3-CA: 14.8;SCLC-21H: 26.2;SH-SY5Y: 13.0;U-266/70: 10.7" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "MAIT T-cell: 3.6;T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Approved Vesicles Vesicles "HPA028181: AB_10603872, HPA073106: " "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 1.2 5.2 20.4 1.7 13.6 1.6 1.5 51.0 40.1 1.1 1.5 1.4 0.0 1.7 1.3 1.2 1.3 1.2 1.6 1.3 16.1 16.3 1.2 1.3 1.2 1.3 8.8 19.5 1.5 1.6 1.2 10.4 1.2 19.9 1.2 1.3 1.6 1.3 1.2 1.2 4.1 1.6 1.3 4.2 1.2 1.5 3.9 2.7 0.0 1.2 0.0 1.3 1.2 0.2 0.4 0.0 0.0 0.2 0.0 3.6 0.1 2.2 1.0 0.9 14.8 0.0 0.0 1.2 0.1 0.1 0.2 0.6 0.5 0.9 3.6 1.6 0.0 0.0 4.3 0.0 0.0 2.5 2.9 0.3 3.6 1.6 0.0 0.7 0.7 0.3 0.0 0.5 0.5 0.0 3.1 1.9 0.0 0.5 1.5 0.4 4.4 4.5 9.8 2.9 5.1 0.2 0.1 26.2 13.0 0.5 0.9 2.6 2.4 1.3 0.0 1.8 2.8 2.0 0.4 10.7 8.5 2.1 3.3 2.0 0.1 0.0 0.2 0.0 0.0 0.2 3.6 0.1 0.0 0.2 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 2.0 0.1 20.4 13.6 51.0 34.3 16.1 16.3 8.8 19.5 19.9 2.7 MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036124 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 83.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 4.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavourable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavourable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" 8.9 4.3 7.0 9.9 8.1 3.7 7.1 7.1 11.8 13.6 15.2 8.4 6.6 11.2 16.7 7.7 8.8 9.5 9.9 25.5 5.0 7.6 4.8 6.1 5.9 4.4 8.9 7.3 19.8 3.6 9.1 10.5 5.5 10.1 13.9 13.9 7.2 8.3 8.6 83.3 5.5 21.3 14.9 5.8 2.5 9.0 24.8 4.8 3.5 5.7 27.4 7.5 16.3 10.6 0.5 1.9 1.4 4.3 1.4 1.4 0.5 15.2 12.4 12.5 9.6 16.4 23.6 13.9 16.3 11.8 15.1 16.9 14.2 5.0 23.9 7.7 19.9 7.6 15.1 9.3 16.0 11.5 8.1 10.8 14.0 13.0 14.3 5.8 13.9 18.1 12.1 25.3 20.3 14.1 8.3 7.3 18.0 10.4 8.4 6.0 10.3 14.2 12.4 21.0 4.5 7.8 8.3 17.5 10.4 19.2 25.1 8.2 11.4 5.7 13.7 29.3 18.9 15.3 16.1 10.0 8.9 8.7 19.6 7.9 12.1 0.0 1.1 1.4 1.4 0.6 1.4 0.2 0.7 1.4 1.9 0.5 0.5 1.0 0.0 1.4 4.3 0.1 0.0 0.5 7.0 8.1 7.1 11.8 5.0 7.6 8.9 7.3 10.1 4.8 MAST3 KIAA0561 ENSG00000099308 "Microtubule associated serine/threonine kinase 3" O60307 19 18097793-18151692 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035061, HPA035062" Uncertain Approved "Nuclear speckles" "Nuclear speckles" "HPA035061: AB_10670585, HPA035062: AB_10671508" "unprognostic (5.94e-3)" "unprognostic (4.75e-2)" "unprognostic (1.70e-1)" "unprognostic (1.02e-1)" "unprognostic (3.38e-1)" "prognostic favourable (2.97e-4)" "unprognostic (1.93e-1)" "unprognostic (4.63e-2)" "unprognostic (1.43e-1)" "unprognostic (3.21e-1)" "prognostic favourable (7.01e-4)" "unprognostic (2.58e-1)" "unprognostic (1.64e-3)" "unprognostic (1.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.58e-3)" "unprognostic (1.26e-3)" 4.6 3.5 20.7 8.3 36.1 12.3 1.8 1.1 72.5 3.8 5.3 19.0 0.2 9.1 3.6 4.9 2.2 4.9 3.1 2.1 19.7 9.3 3.6 6.4 4.6 9.9 13.0 33.6 4.6 14.3 7.1 7.7 2.6 13.0 2.7 4.4 0.7 4.6 4.2 2.6 6.9 8.8 3.0 7.9 11.4 3.9 2.1 12.5 1.8 2.4 0.3 9.4 3.3 2.4 4.4 10.3 23.2 9.7 5.8 8.4 3.1 3.3 4.9 2.3 10.0 6.8 5.5 5.4 3.4 2.2 2.4 3.4 4.9 4.6 8.6 5.1 3.4 1.8 3.3 1.9 1.7 7.3 4.1 3.9 5.2 7.8 5.7 2.1 13.2 6.2 5.7 3.6 1.4 1.0 4.0 5.7 2.7 5.9 4.4 6.9 2.4 6.1 11.9 1.9 6.3 1.8 1.5 3.7 6.1 4.7 2.8 2.0 3.1 4.9 3.9 3.1 3.3 12.9 1.4 6.2 8.3 7.9 6.7 11.1 2.8 0.1 4.5 9.4 8.4 5.6 6.2 4.1 4.7 3.3 2.1 4.4 3.7 6.4 23.2 5.8 9.7 10.3 5.0 3.1 20.7 36.1 1.1 72.5 19.7 9.3 13.0 33.6 13.0 12.5 MAST4 KIAA0303 ENSG00000069020 "Microtubule associated serine/threonine kinase family member 4" O15021 5 66596361-67169595 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 17.5;HDLM-2: 22.2;HEL: 18.4;RT4: 22.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000544 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA000544: AB_1079315" "unprognostic (1.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.80e-1)" "unprognostic (4.99e-3)" "unprognostic (2.83e-2)" "prognostic favourable (5.18e-5)" "unprognostic (9.01e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-2)" "unprognostic (9.47e-2)" "unprognostic (5.03e-2)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (1.37e-2)" "unprognostic (2.63e-1)" "unprognostic (2.63e-1)" "unprognostic (3.08e-2)" 16.2 12.9 10.2 6.9 11.8 2.5 12.6 6.2 19.4 13.9 6.9 6.3 6.3 6.3 14.4 8.9 31.2 11.6 9.7 24.5 9.9 8.1 14.2 9.5 13.1 5.0 6.5 9.2 20.2 5.9 35.6 16.7 18.4 11.1 10.1 5.3 5.7 13.7 8.7 12.7 16.9 6.8 11.4 5.6 6.0 8.2 10.7 5.0 37.5 8.1 21.8 20.6 13.6 22.3 3.4 1.1 12.1 0.9 2.4 7.5 1.4 7.4 4.1 2.0 0.1 6.8 6.1 4.9 1.7 2.6 0.6 0.5 3.8 2.0 0.5 3.5 1.4 6.7 6.3 17.5 0.7 22.2 2.0 18.4 2.3 1.6 0.5 0.0 6.5 10.1 9.7 3.8 7.7 13.9 1.7 2.1 4.7 6.5 2.6 0.1 1.3 3.3 0.6 1.8 0.4 1.6 22.5 3.0 2.4 2.2 0.9 0.1 1.5 0.1 13.2 1.6 2.2 2.4 2.8 5.4 2.4 0.1 4.2 0.0 1.3 12.1 0.4 0.8 1.2 0.5 2.9 3.4 4.7 1.2 0.4 2.1 5.0 2.1 4.1 2.4 0.9 1.1 7.5 1.4 10.2 11.8 6.2 19.4 9.9 8.1 6.5 9.2 11.1 5.0 MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27186924 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm Nucleoplasm "HPA027175: AB_1853591, HPA054273: " "unprognostic (4.10e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-2)" "unprognostic (3.14e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" "prognostic unfavourable (2.52e-6)" "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.05e-2)" "prognostic unfavourable (4.81e-5)" "unprognostic (3.78e-2)" "prognostic unfavourable (1.71e-6)" "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" 9.1 7.0 3.6 8.9 6.1 21.1 8.3 4.0 7.5 7.4 7.6 3.8 5.7 5.7 6.0 6.7 12.3 5.4 5.3 5.6 6.8 4.5 6.5 7.1 10.2 14.8 5.4 5.7 7.0 12.7 6.7 6.3 14.2 6.7 5.5 7.1 5.6 8.0 4.7 4.0 10.1 10.0 6.1 5.6 8.7 6.2 11.3 2.3 21.1 6.5 4.3 12.3 8.7 7.5 3.9 2.6 5.6 4.9 2.3 4.0 1.8 11.7 9.5 18.1 6.7 2.8 4.1 10.7 17.6 7.4 29.2 36.0 11.4 11.8 9.4 6.7 7.4 11.4 11.5 6.9 20.8 8.0 11.1 11.1 6.6 6.6 1.6 4.2 8.4 2.4 3.1 17.6 3.5 6.3 8.4 21.3 17.7 7.8 13.7 4.7 13.4 3.9 8.8 30.2 7.7 7.2 4.4 8.1 11.6 11.1 7.4 7.8 7.5 9.0 5.4 7.3 15.3 18.6 15.4 2.6 4.1 13.9 8.0 12.9 6.0 0.1 4.4 3.8 2.0 4.3 3.0 2.6 2.5 1.8 2.5 3.9 2.5 2.3 5.6 2.3 4.9 2.6 4.0 1.8 3.6 6.1 4.0 7.5 6.8 4.5 5.4 5.7 6.7 2.3 MAT1A "MAT, MATA1, SAMS, SAMS1" ENSG00000151224 "Methionine adenosyltransferase 1A" Q00266 10 80271820-80289684 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 178.8" "Cell line enriched" "Detected in some" 15 "Hep G2: 44.8" "Cancer enriched" "Detected in many" 54 "liver cancer: 209.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA048627 Supported 530000 "HPA048627: " "unprognostic (6.92e-2)" "unprognostic (2.63e-1)" "unprognostic (2.88e-2)" "unprognostic (9.43e-2)" "unprognostic (3.79e-2)" "unprognostic (2.49e-2)" "unprognostic (2.03e-3)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (2.58e-2)" "unprognostic (1.76e-1)" "unprognostic (8.66e-2)" "unprognostic (1.11e-16)" "unprognostic (8.59e-3)" "unprognostic (9.90e-2)" "unprognostic (3.58e-1)" "unprognostic (5.98e-2)" 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 12.5 0.1 0.2 0.2 0.1 0.0 0.0 0.3 178.8 0.1 0.1 0.1 0.0 0.7 9.9 0.0 0.6 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.7 0.0 0.0 0.4 0.2 0.0 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 44.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 MAT2A "MATA2, MATII, SAMS2" ENSG00000168906 "Methionine adenosyltransferase 2A" P31153 2 85539165-85545280 "Enzymes, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 205.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009968, HPA043028" Approved Approved Nucleoplasm,Cytosol 950000 Nucleoplasm Cytosol "CAB009968: AB_675710, HPA043028: AB_10960707" "unprognostic (1.38e-3)" "unprognostic (2.58e-2)" "unprognostic (3.96e-2)" "prognostic unfavourable (5.29e-5)" "unprognostic (9.89e-3)" "unprognostic (5.90e-3)" "prognostic unfavourable (4.87e-4)" "prognostic favourable (8.94e-4)" "prognostic unfavourable (5.94e-5)" "unprognostic (4.07e-2)" "unprognostic (2.02e-1)" "unprognostic (2.59e-2)" "unprognostic (9.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (1.77e-2)" 55.9 68.9 37.4 35.3 54.1 20.4 30.3 37.5 50.0 28.6 35.3 74.5 39.7 33.6 35.8 59.8 33.5 44.9 51.6 35.0 41.7 28.5 52.3 26.4 32.9 27.0 74.8 37.6 44.2 205.8 38.8 60.5 29.3 48.9 40.6 36.8 35.0 28.2 31.3 51.4 33.7 35.8 47.6 57.7 24.7 44.6 34.9 69.4 22.7 94.0 34.1 30.8 46.9 33.4 13.8 15.3 4.9 17.2 16.9 22.8 14.9 29.7 44.2 51.9 32.2 35.7 43.7 30.7 37.4 34.5 39.4 42.1 36.1 100.4 69.8 24.7 45.4 46.4 65.2 55.8 50.7 35.3 47.9 41.7 64.0 31.1 65.3 61.8 46.6 39.5 56.7 42.5 29.7 37.3 46.8 55.0 89.4 25.5 56.3 68.1 34.4 56.9 60.0 49.2 45.2 59.5 47.2 40.9 37.7 33.8 32.7 60.3 27.7 33.2 36.3 48.4 29.2 26.6 44.7 33.9 26.9 50.5 31.6 77.6 25.4 4.8 15.2 4.9 15.4 17.2 22.8 13.8 17.5 16.2 15.3 12.2 16.4 14.3 1.6 16.9 13.7 10.9 15.3 14.9 37.4 54.1 37.5 50.0 41.7 28.5 74.8 37.6 48.9 69.4 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 29.3;bone marrow: 19.1;brain: 27.4" "Cell line enhanced" "Detected in some" "HL-60: 40.7;HMC-1: 12.5;K-562: 18.1;MCF7: 13.2;NB-4: 28.4;SCLC-21H: 12.4;THP-1: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 19.4;NK-cell: 29.3" "Group enriched" "Detected in many" 54 "NK-cells: 29.3;T-cells: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favourable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 11.2 1.6 22.1 6.8 18.1 19.1 2.2 1.5 27.4 1.5 2.3 1.7 0.0 7.0 1.2 0.4 1.1 4.7 5.1 1.7 25.1 10.0 1.1 2.8 7.3 9.6 7.0 11.0 1.0 1.6 0.1 1.4 1.4 6.1 1.2 1.4 0.6 3.8 1.0 0.8 1.6 6.7 1.1 2.8 14.8 4.1 2.1 1.3 3.5 0.9 0.0 4.5 2.4 0.7 0.4 0.3 0.4 0.0 29.3 19.4 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 4.1 5.4 0.1 0.0 0.0 7.0 4.5 0.5 1.1 0.0 40.7 12.5 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 13.2 0.1 28.4 3.3 0.1 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 10.7 1.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 13.2 0.0 2.5 12.2 0.3 0.4 1.2 7.1 0.4 29.3 0.0 0.1 0.1 2.7 22.1 18.1 1.5 27.4 25.1 10.0 7.0 11.0 6.1 1.3 MBOAT2 "FLJ14415, FLJ90298, OACT2" ENSG00000143797 "Membrane bound O-acyltransferase domain containing 2" Q6ZWT7 2 8852690-9003813 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 34.7" "Cell line enhanced" "Detected in many" "SK-BR-3: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 6.3;eosinophil: 2.8;neutrophil: 6.7" "Lineage enriched" "Detected in single" 8 "granulocytes: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014836 Uncertain Approved Vesicles Vesicles "HPA014836: AB_1854745" "unprognostic (2.49e-1)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "prognostic unfavourable (2.13e-9)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (2.38e-1)" "unprognostic (3.97e-3)" "unprognostic (3.09e-1)" "unprognostic (3.00e-1)" "unprognostic (1.03e-3)" "unprognostic (1.70e-1)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "unprognostic (3.04e-2)" "unprognostic (6.66e-2)" "prognostic unfavourable (5.32e-4)" 2.3 2.9 12.8 2.9 18.0 24.2 10.1 10.1 20.2 6.0 8.2 16.6 1.2 3.1 5.3 3.5 14.2 3.7 4.3 5.1 14.7 12.4 8.0 1.3 10.9 2.9 23.3 10.3 6.8 2.1 34.7 5.5 3.8 16.2 16.1 9.3 6.4 5.6 4.1 1.2 12.3 4.3 4.6 18.5 2.5 6.9 2.7 17.8 1.9 5.3 16.1 10.3 4.4 7.5 0.0 0.8 6.7 0.7 0.0 0.2 0.3 8.3 2.5 7.8 3.3 3.5 7.9 4.6 4.0 1.4 5.2 3.5 0.7 13.3 2.4 4.8 9.5 6.4 6.9 8.1 7.9 7.4 11.9 10.0 3.7 0.0 4.4 0.0 3.2 5.7 4.8 5.0 3.4 2.7 8.5 1.9 4.5 2.1 2.9 0.2 3.1 9.9 4.4 12.3 0.1 7.7 1.2 4.7 14.3 4.2 25.1 3.9 4.7 2.8 1.5 9.2 4.9 7.1 11.4 0.7 0.2 2.6 14.5 1.4 3.1 6.3 0.7 2.8 0.0 0.2 0.0 0.0 0.2 0.1 0.8 0.0 0.2 0.1 6.7 0.0 0.2 0.1 0.0 0.3 12.8 18.0 10.1 15.8 14.7 12.4 23.3 10.3 16.2 17.8 MBOAT7 "BB1, hMBOA-7, LENG4, LPIAT" ENSG00000125505 "Membrane bound O-acyltransferase domain containing 7" Q96N66 19 54173412-54189882 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "basophil: 15.7;eosinophil: 30.6;neutrophil: 30.0" "Lineage enriched" "Detected in many" 10 "granulocytes: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055967 Approved Approved Cytosol Cytosol "HPA055967: " "unprognostic (1.89e-2)" "unprognostic (2.60e-2)" "unprognostic (2.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.54e-2)" "unprognostic (5.95e-2)" "prognostic unfavourable (5.55e-6)" "prognostic unfavourable (5.13e-4)" "unprognostic (5.36e-2)" "unprognostic (2.31e-2)" "unprognostic (1.08e-2)" "unprognostic (2.81e-1)" "prognostic unfavourable (6.62e-5)" "unprognostic (1.31e-1)" "unprognostic (4.75e-2)" "unprognostic (3.95e-1)" "prognostic favourable (4.31e-4)" 10.7 63.1 16.8 14.8 24.2 15.9 7.9 11.3 37.8 10.3 17.7 9.2 15.6 30.3 10.5 8.0 10.5 11.5 14.3 6.9 18.5 23.4 10.5 11.6 11.5 14.7 10.0 18.8 15.1 24.4 23.8 12.4 11.9 21.6 11.4 6.1 8.1 10.8 28.8 7.9 10.0 28.5 6.5 9.2 14.4 16.4 30.8 6.8 7.6 12.7 5.0 6.3 22.6 17.5 0.3 2.9 30.6 2.1 0.9 0.5 0.8 14.0 8.4 1.3 13.8 4.5 3.6 12.2 24.7 8.8 5.7 11.3 4.8 16.0 3.6 11.1 5.3 28.8 0.0 5.0 1.1 5.0 16.4 3.9 9.0 3.1 4.4 8.9 56.5 6.6 3.4 2.8 1.9 10.2 14.5 11.6 2.0 8.5 2.6 3.1 5.8 17.9 8.3 2.4 7.4 5.7 17.0 0.5 3.7 16.5 10.0 5.0 10.2 0.8 20.4 12.1 4.3 3.6 9.7 5.3 9.2 1.5 17.4 6.3 8.0 15.7 2.1 30.6 0.2 1.5 0.5 0.2 0.2 0.2 2.9 0.3 0.1 0.2 30.0 0.9 0.8 0.8 0.2 0.8 16.8 24.2 11.3 37.8 18.5 23.4 10.0 18.8 21.6 6.8 MBTPS1 "KIAA0091, PCSK8, S1P, SKI-1" ENSG00000140943 "Membrane bound transcription factor peptidase, site 1" Q14703 16 84053761-84116906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056109 Supported "HPA056109: " "unprognostic (1.50e-1)" "unprognostic (9.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (2.50e-1)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "prognostic favourable (2.21e-5)" "unprognostic (2.62e-1)" "unprognostic (2.92e-1)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" 26.6 25.3 15.2 17.9 32.0 13.2 27.2 29.9 30.2 27.5 23.6 20.5 21.5 15.8 33.5 22.2 18.8 29.2 20.4 31.5 15.7 18.2 23.4 28.9 22.1 17.1 14.8 15.9 34.3 32.6 47.5 38.7 28.5 15.9 24.0 21.2 33.1 29.7 26.8 16.2 18.7 19.0 25.9 11.4 21.8 23.5 17.7 16.1 24.0 36.7 16.7 23.2 26.1 19.6 10.9 11.5 12.8 14.3 14.4 16.7 15.4 15.2 19.4 17.5 24.2 41.2 33.5 13.7 25.7 39.9 22.8 17.3 13.7 22.7 14.7 26.8 36.9 16.9 15.9 17.9 25.4 13.2 17.9 10.7 18.8 19.2 19.9 25.9 23.7 34.4 25.9 21.0 18.1 29.6 13.9 13.0 13.8 26.5 14.2 14.5 16.2 13.9 18.5 9.3 10.6 18.5 12.7 13.3 16.7 49.7 13.8 19.2 43.2 23.9 31.4 23.7 17.4 14.1 12.1 16.5 30.5 28.2 17.3 15.8 14.4 6.6 14.3 12.8 15.8 12.1 16.2 10.9 13.6 14.7 11.5 9.9 16.7 14.8 4.1 14.4 9.8 6.4 8.7 15.4 15.2 32.0 29.9 30.2 15.7 18.2 14.8 15.9 15.9 16.1 MBTPS2 "KFSD, S2P" ENSG00000012174 "Membrane bound transcription factor peptidase, site 2" O43462 X 21839636-21885424 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Ichthyosis, Osteogenesis imperfecta, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005494, CAB009486" Approved Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "CAB009486: AB_2140370, HPA005494: AB_1079329" "unprognostic (7.97e-3)" "unprognostic (9.12e-2)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (7.22e-2)" "unprognostic (3.32e-1)" "unprognostic (9.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (8.38e-2)" "unprognostic (7.76e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (3.05e-2)" 12.0 17.4 9.3 7.2 13.9 2.5 12.7 20.8 18.5 11.8 9.3 13.4 6.9 7.6 14.7 9.1 9.3 10.9 10.1 11.6 9.9 10.7 13.9 26.0 8.6 6.6 10.6 13.0 18.7 12.2 17.9 15.6 22.3 17.4 15.7 9.1 12.4 14.1 13.1 14.5 8.2 8.1 14.6 14.6 7.5 9.1 6.9 7.0 7.1 13.1 7.4 6.7 11.4 9.1 3.9 6.9 1.5 4.8 4.6 5.9 3.3 9.1 19.0 9.1 9.2 11.5 14.3 4.4 13.5 13.8 12.9 11.3 7.5 12.6 7.9 7.1 14.4 8.6 12.5 7.8 16.0 5.9 10.0 3.9 12.1 6.2 15.8 8.4 3.9 13.5 8.4 19.5 14.4 9.9 10.9 8.9 14.7 5.7 3.4 4.4 8.5 14.1 4.3 16.9 8.8 9.0 4.6 2.2 18.7 19.1 12.1 16.7 16.3 7.2 11.7 16.3 3.8 23.7 10.1 10.9 13.8 3.8 18.1 3.5 15.6 0.1 4.3 1.5 4.5 4.8 4.2 3.9 3.5 4.1 6.9 3.8 4.7 5.6 0.5 4.6 4.8 4.8 5.9 3.3 9.3 13.9 20.8 18.5 9.9 10.7 10.6 13.0 17.4 7.0 MCAT "fabD, FASN2C, MCT, MCT1, MT, NET62" ENSG00000100294 "Malonyl-CoA-acyl carrier protein transacylase" Q8IVS2 22 43132206-43143394 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003122, HPA035471" Approved Supported Mitochondria Mitochondria "HPA003122: , HPA035471: AB_10670590" "unprognostic (1.05e-1)" "unprognostic (1.57e-2)" "unprognostic (1.39e-2)" "prognostic favourable (5.53e-4)" "unprognostic (3.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-3)" "unprognostic (4.71e-2)" "unprognostic (5.13e-2)" "unprognostic (2.94e-1)" "unprognostic (1.32e-1)" "unprognostic (9.86e-2)" "prognostic favourable (2.18e-4)" "prognostic favourable (3.89e-4)" "unprognostic (3.67e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-1)" 10.4 18.2 13.3 8.2 17.2 11.0 12.8 10.4 24.6 10.6 11.9 9.4 10.7 9.5 11.0 17.2 12.3 20.7 21.4 12.9 14.4 14.2 25.6 24.3 8.6 7.1 12.0 12.0 14.4 16.2 20.3 14.3 9.2 15.1 12.8 10.6 9.9 14.5 10.2 17.7 11.7 9.7 8.6 6.0 7.6 12.1 19.6 5.2 18.4 20.1 14.0 9.9 8.5 8.1 10.2 13.9 2.5 9.5 11.6 10.3 5.6 7.1 9.4 6.7 11.7 5.6 6.0 6.8 8.0 7.1 10.8 10.1 9.4 7.3 12.0 8.3 5.9 12.0 12.6 10.6 8.1 4.1 37.3 4.5 10.8 10.4 9.0 21.3 5.4 4.5 10.3 10.5 8.4 7.7 10.5 4.9 5.2 13.2 9.9 23.2 6.4 16.7 13.2 6.6 19.0 13.5 6.2 8.8 4.7 8.6 16.8 12.1 8.7 13.8 4.6 4.7 9.3 10.2 11.2 8.8 9.0 8.6 10.1 8.1 5.6 0.0 9.5 0.7 7.7 9.1 10.3 8.3 8.6 10.1 13.9 10.2 10.1 7.1 2.5 11.6 5.5 13.7 5.5 5.6 13.3 17.2 10.4 24.6 14.4 14.2 12.0 12.0 15.1 5.2 MCCC1 MCCA ENSG00000078070 "Methylcrotonoyl-CoA carboxylase 1" Q96RQ3 3 183015218-183116075 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008310 Approved Supported Mitochondria "Intracellular and membrane" Mitochondria "HPA008310: AB_1853620" "unprognostic (4.01e-2)" "unprognostic (1.83e-3)" "unprognostic (2.05e-2)" "unprognostic (2.59e-3)" "unprognostic (3.46e-2)" "unprognostic (4.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-3)" "unprognostic (2.57e-3)" "unprognostic (9.82e-2)" "unprognostic (9.74e-2)" "unprognostic (7.65e-2)" "prognostic favourable (3.68e-4)" "unprognostic (4.73e-1)" "unprognostic (2.21e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" 25.1 26.0 14.1 10.4 16.4 9.0 24.6 23.1 20.6 9.0 12.6 15.1 10.1 12.6 11.0 11.4 15.8 9.5 11.6 24.4 12.2 10.1 42.4 41.1 13.8 8.0 17.0 14.4 12.8 32.3 10.2 15.8 5.5 13.4 11.4 13.7 9.9 14.2 15.6 19.4 11.5 10.1 11.3 10.5 8.3 17.7 8.9 16.4 8.9 14.0 8.5 13.2 23.2 9.5 13.1 19.4 17.1 11.3 18.9 11.6 7.6 14.1 5.4 3.4 3.6 15.0 6.8 6.9 6.5 9.1 7.2 8.2 7.4 5.7 15.6 10.6 5.7 7.3 5.2 4.3 9.2 5.2 5.8 13.3 6.2 7.8 9.9 8.9 7.6 7.7 4.9 3.4 7.7 9.6 7.3 8.2 8.0 11.6 8.6 4.4 3.8 5.9 7.2 7.7 20.0 10.5 22.5 7.7 5.6 24.9 34.4 7.0 52.6 12.5 4.6 5.5 4.4 4.4 9.6 8.4 15.4 15.8 6.0 12.8 5.1 8.5 9.7 17.1 8.3 11.3 9.4 13.1 10.8 9.0 19.4 11.1 11.6 10.4 1.6 18.9 11.2 12.7 6.8 7.6 14.1 16.4 23.1 20.6 12.2 10.1 17.0 14.4 13.4 16.4 MCCC2 MCCB ENSG00000131844 "Methylcrotonoyl-CoA carboxylase 2" Q9HCC0 5 71587288-71658704 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Ligase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 74.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria Mitochondria "HPA038300: AB_2675941, HPA038301: AB_10670661, HPA061546: AB_2684557" "unprognostic (2.39e-1)" "unprognostic (6.89e-3)" "prognostic favourable (3.62e-4)" "unprognostic (1.79e-2)" "unprognostic (1.89e-2)" "unprognostic (8.07e-2)" "prognostic favourable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-1)" "unprognostic (5.39e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "prognostic favourable (6.43e-8)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" 12.4 29.4 9.2 11.8 13.6 2.7 30.5 7.9 10.0 11.2 15.3 12.2 15.1 13.0 9.7 20.0 14.5 9.1 12.3 74.3 7.6 8.1 35.6 61.9 8.4 11.6 7.8 8.0 9.6 18.9 14.1 10.3 15.1 13.4 24.6 18.1 12.8 20.6 29.4 17.6 10.8 14.1 7.8 17.0 11.0 13.6 6.9 6.9 9.4 22.2 13.3 14.3 15.7 8.5 8.8 16.7 1.7 11.5 12.9 10.2 6.7 11.8 16.3 7.0 26.9 7.5 7.8 12.0 5.6 9.5 11.7 8.5 28.7 15.1 27.5 20.9 8.2 9.8 12.2 18.9 14.7 14.5 15.6 14.9 8.5 31.5 13.2 7.4 14.2 9.9 9.9 10.7 8.5 10.3 18.8 10.3 8.1 32.3 0.1 13.5 9.2 9.2 14.4 20.2 40.4 30.4 21.4 11.1 12.3 24.7 36.7 12.0 30.4 18.8 7.5 4.8 7.4 8.6 15.2 7.4 13.7 17.0 7.8 20.6 11.8 1.7 7.4 1.6 6.1 11.5 7.9 8.8 7.9 6.9 16.7 8.6 8.0 8.7 1.2 12.9 6.8 7.4 10.2 6.7 9.2 13.6 7.9 10.0 7.6 8.1 7.8 8.0 13.4 6.9 MCEE GLOD2 ENSG00000124370 "Methylmalonyl-CoA epimerase" Q96PE7 2 71109684-71130239 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035196 Approved Nucleoli "Intracellular and membrane" 16000 Nucleoli "HPA035196: AB_10601871" "unprognostic (7.65e-2)" "unprognostic (8.20e-2)" "unprognostic (3.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.35e-1)" "prognostic favourable (4.76e-4)" "prognostic favourable (5.78e-4)" "unprognostic (4.86e-3)" "unprognostic (6.48e-2)" "unprognostic (1.08e-1)" "unprognostic (7.43e-3)" "unprognostic (8.59e-2)" "unprognostic (9.40e-3)" "unprognostic (4.90e-2)" "unprognostic (3.55e-1)" "unprognostic (6.51e-2)" "unprognostic (5.38e-2)" 10.5 20.4 8.5 10.1 9.2 4.3 18.9 10.5 9.8 14.1 13.8 9.4 24.6 11.1 8.8 19.7 16.9 8.6 12.6 19.8 6.6 6.2 18.8 39.7 9.1 9.5 13.1 6.6 12.4 29.0 9.8 24.5 9.9 9.1 13.7 13.5 11.1 28.9 20.5 18.2 15.2 14.9 10.9 11.5 10.1 13.1 5.7 11.4 9.3 11.0 18.7 10.9 13.0 13.3 15.9 17.6 20.0 18.4 11.2 24.9 11.1 6.3 3.1 5.6 4.0 19.2 26.2 16.4 9.8 12.5 5.0 7.6 7.6 7.9 9.9 3.0 9.7 6.7 6.8 5.1 5.2 9.1 5.9 6.7 8.7 22.0 10.8 7.5 5.6 17.4 7.4 3.4 6.7 5.7 8.8 17.2 4.8 8.1 5.6 8.8 5.2 7.6 6.6 6.4 18.3 7.7 5.1 6.5 4.7 3.7 21.7 9.7 17.2 7.2 7.3 5.9 4.5 5.9 3.9 16.5 6.8 10.5 9.5 12.3 5.3 13.0 18.3 20.0 12.8 18.4 17.3 15.9 15.7 12.3 14.9 13.2 14.6 12.3 4.5 11.2 17.6 17.6 24.9 11.1 8.5 9.2 10.5 9.8 6.6 6.2 13.1 6.6 9.1 11.4 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598223-127622436 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 69.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000303, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm 8600 Nucleoplasm "CAB000303: AB_322519, HPA031495: AB_2673904, HPA031496: " "unprognostic (2.43e-1)" "prognostic favourable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavourable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 2.9 3.7 2.1 24.3 4.0 32.5 3.5 6.7 3.2 4.7 7.1 3.3 2.2 4.7 4.7 5.9 11.2 4.8 5.4 3.6 2.0 2.3 3.9 3.4 3.4 14.6 2.2 3.5 5.1 3.0 2.4 2.4 26.4 3.0 3.2 6.0 2.5 4.7 1.9 7.0 6.0 7.1 2.9 2.9 13.3 3.8 20.3 3.9 69.9 4.1 16.6 20.7 3.4 5.1 10.4 3.6 0.9 1.4 5.8 10.6 3.4 24.8 21.2 23.2 20.3 1.4 3.0 22.7 13.1 8.4 26.3 28.7 35.1 16.5 26.8 12.8 6.4 20.0 41.5 15.0 16.4 22.1 25.9 44.3 28.4 25.5 0.9 41.4 19.4 1.6 1.7 17.8 2.7 8.2 22.1 24.6 9.6 33.0 38.3 30.4 34.0 18.7 43.1 33.3 38.4 5.4 19.3 28.9 21.9 33.5 10.0 3.4 21.4 32.5 4.2 20.5 17.5 25.2 17.6 25.5 28.9 66.6 14.2 31.4 7.8 0.0 0.6 0.2 4.7 1.4 5.9 10.4 4.1 5.5 2.8 9.2 3.9 5.0 0.9 5.8 0.3 3.6 10.6 3.4 2.1 4.0 6.7 3.2 2.0 2.3 2.2 3.5 3.0 3.9 MCM3 ENSG00000112118 "Minichromosome maintenance complex component 3" P25205 6 52264009-52284881 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 82.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002162, HPA004789, HPA004790" Supported Enhanced Nucleoplasm 29000 Nucleoplasm "CAB002162: AB_564115, HPA004789: AB_1079336, HPA004790: AB_1079335" "unprognostic (9.14e-2)" "prognostic favourable (1.89e-4)" "unprognostic (2.37e-1)" "unprognostic (1.53e-2)" "unprognostic (2.14e-1)" "unprognostic (5.48e-3)" "prognostic unfavourable (1.40e-4)" "unprognostic (1.36e-1)" "prognostic unfavourable (4.40e-5)" "unprognostic (1.01e-3)" "unprognostic (2.96e-2)" "unprognostic (1.15e-1)" "unprognostic (8.35e-2)" "unprognostic (1.16e-2)" "unprognostic (1.00e-1)" "prognostic favourable (3.13e-5)" "unprognostic (1.34e-2)" 17.3 10.9 8.5 29.7 10.5 22.3 15.3 10.7 9.7 15.9 17.2 9.5 20.2 9.0 21.2 13.0 21.7 15.5 15.8 15.4 7.4 6.6 16.1 12.6 13.7 30.1 8.9 5.8 20.0 13.8 16.0 7.4 24.7 10.0 15.9 19.2 12.7 12.6 23.4 12.1 15.0 17.8 17.7 9.5 23.2 15.3 16.1 10.5 82.5 12.9 20.1 35.7 19.1 15.3 21.1 12.9 11.4 13.3 22.2 29.4 18.6 30.2 20.1 35.1 33.1 7.6 6.9 23.1 22.5 17.3 38.4 39.5 41.2 16.5 33.1 22.6 13.1 24.1 46.3 27.5 38.9 37.2 43.8 62.5 40.5 58.0 2.0 61.3 25.6 4.1 6.4 28.2 7.9 19.6 50.8 76.3 19.8 20.0 61.7 47.4 29.1 14.2 54.8 53.8 44.2 17.0 32.2 35.7 27.3 23.6 13.6 20.4 26.8 43.5 10.0 26.3 28.3 27.1 33.6 22.6 25.8 58.9 22.6 53.2 30.7 11.1 8.0 11.4 22.9 13.3 19.7 21.1 23.3 23.0 12.9 19.2 22.6 24.0 1.1 22.2 7.4 8.3 29.4 18.6 8.5 10.5 10.7 9.7 7.4 6.6 8.9 5.8 10.0 10.5 MCM4 "CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21" ENSG00000104738 "Minichromosome maintenance complex component 4" P33991 8 47960185-47978160 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 56.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004497, HPA004873, HPA031052" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB004497: AB_627916, HPA004873: AB_1079337, HPA031052: " "unprognostic (4.55e-2)" "unprognostic (3.16e-3)" "prognostic favourable (2.19e-4)" "prognostic unfavourable (2.84e-5)" "unprognostic (7.71e-2)" "unprognostic (1.05e-1)" "prognostic unfavourable (1.23e-4)" "unprognostic (1.12e-3)" "prognostic unfavourable (1.15e-4)" "unprognostic (2.65e-2)" "prognostic unfavourable (2.38e-4)" "unprognostic (5.16e-2)" "prognostic unfavourable (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.70e-2)" "unprognostic (1.40e-1)" 4.9 8.7 6.7 18.4 12.6 33.1 9.3 13.9 14.8 6.7 11.9 6.9 3.6 8.3 4.7 7.8 21.6 5.9 6.8 8.3 6.6 7.1 8.0 6.6 4.4 20.3 5.9 7.7 5.3 5.5 4.3 4.1 29.2 7.7 4.2 13.2 5.3 9.0 3.1 8.7 16.2 10.3 5.9 6.4 10.1 6.3 39.0 4.1 56.6 4.0 21.8 23.7 8.0 9.5 5.1 4.9 3.4 4.3 4.9 12.9 4.5 34.1 21.2 39.4 14.4 3.9 6.8 17.4 26.0 17.1 32.8 37.2 22.5 31.0 37.0 14.6 12.9 25.2 49.6 21.1 37.1 11.6 32.8 63.4 25.5 24.9 1.0 33.8 13.9 4.1 4.2 26.1 9.3 11.5 34.9 30.8 22.6 21.1 74.8 24.7 42.7 9.2 47.6 30.9 24.1 11.9 30.6 37.8 18.2 52.7 22.0 7.8 26.3 17.8 7.7 25.1 24.4 28.1 23.8 10.1 24.2 75.5 20.1 31.4 22.4 3.4 2.1 1.5 5.5 3.7 2.7 5.1 5.0 6.8 4.9 2.1 4.6 3.4 0.1 4.9 4.3 1.7 12.9 4.5 6.7 12.6 13.9 14.8 6.6 7.1 5.9 7.7 7.7 4.1 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400063-35425430 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.0;lymphoid tissue: 60.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: " "unprognostic (6.71e-2)" "prognostic favourable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavourable (1.78e-4)" "prognostic unfavourable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavourable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 12.1 4.9 6.1 27.5 9.0 57.0 9.1 6.7 5.7 10.4 11.5 12.3 5.0 9.5 10.8 10.8 15.8 8.7 9.4 5.2 4.4 3.4 6.8 8.0 9.3 31.1 8.8 3.7 17.9 10.8 6.2 3.6 19.3 5.8 7.2 8.3 6.5 8.9 5.1 8.8 10.3 16.7 6.0 7.8 31.2 8.4 16.4 8.8 60.6 9.0 17.7 33.0 8.7 9.6 46.8 30.9 19.0 26.0 21.3 32.9 24.0 38.9 28.3 22.4 22.8 2.1 4.4 19.6 26.0 13.8 38.9 37.0 18.8 19.4 25.8 15.1 13.2 19.4 22.3 20.6 12.5 20.8 41.0 36.8 28.4 37.5 0.7 75.9 33.3 2.4 1.9 23.2 6.3 17.2 22.7 38.6 14.7 32.1 61.8 25.3 29.7 16.8 70.0 31.7 32.5 7.7 22.6 17.3 18.4 35.8 14.4 8.0 15.0 29.0 10.1 39.3 29.9 24.4 26.8 21.5 26.4 48.5 25.4 28.7 30.0 19.0 20.7 14.5 18.4 24.1 13.1 46.8 16.1 19.4 27.1 37.0 13.1 14.8 9.9 21.3 26.0 30.9 32.9 24.0 6.1 9.0 6.7 5.7 4.4 3.4 8.8 3.7 5.8 8.8 MCM6 Mis5 ENSG00000076003 "Minichromosome maintenance complex component 6" Q14566 2 135839626-135876426 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 66.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004818, CAB009577" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB009577: AB_2266309, HPA004818: AB_1079339" "unprognostic (6.73e-2)" "unprognostic (6.68e-3)" "unprognostic (1.22e-3)" "unprognostic (3.60e-3)" "unprognostic (8.98e-2)" "unprognostic (4.34e-2)" "prognostic unfavourable (5.70e-7)" "unprognostic (1.71e-2)" "prognostic unfavourable (1.09e-5)" "unprognostic (2.36e-2)" "unprognostic (1.36e-2)" "unprognostic (3.53e-2)" "prognostic unfavourable (8.29e-12)" "unprognostic (2.84e-1)" "unprognostic (9.02e-2)" "unprognostic (7.42e-2)" "unprognostic (1.68e-1)" 11.3 6.3 7.2 17.7 8.4 23.1 9.5 12.3 9.4 9.1 11.9 5.1 2.9 8.7 10.4 8.8 12.6 8.7 7.6 6.0 5.0 5.5 6.8 7.0 8.5 23.9 4.9 8.0 10.9 4.3 6.2 3.4 10.9 5.9 8.6 12.2 6.2 6.9 6.7 8.2 8.9 16.7 10.4 7.2 14.1 8.0 13.2 3.7 66.3 5.1 11.4 27.5 10.8 9.8 5.5 9.4 5.3 4.0 7.0 13.9 5.6 23.0 14.2 31.0 19.7 6.7 8.7 12.2 16.8 12.8 19.6 21.9 29.0 17.7 40.4 12.4 12.2 13.7 31.3 15.4 21.0 20.7 21.6 40.1 21.1 9.1 3.1 48.1 17.9 5.1 2.0 14.3 4.4 13.3 28.6 34.2 14.4 23.6 58.7 35.4 27.9 14.3 29.1 37.1 37.0 9.8 20.4 19.5 16.6 22.2 10.6 10.6 12.2 30.3 6.5 13.7 11.4 14.7 12.7 20.5 33.4 53.2 19.1 36.8 16.2 5.3 1.4 0.9 7.6 4.0 7.1 5.5 10.5 9.2 4.6 3.2 9.6 11.8 0.8 7.0 3.6 9.4 13.9 5.6 7.2 8.4 12.3 9.4 5.0 5.5 4.9 8.0 5.9 3.7 MCM7 "CDC47, MCM2, PPP1R104" ENSG00000166508 "Minichromosome maintenance complex component 7" P33993 7 100092728-100101940 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002163, HPA003898, CAB016312" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB002163: AB_564113, CAB016312: AB_627235, HPA003898: AB_1853632" "unprognostic (1.87e-1)" "prognostic favourable (1.28e-4)" "unprognostic (1.36e-1)" "unprognostic (5.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.03e-2)" "prognostic unfavourable (2.18e-4)" "unprognostic (2.08e-2)" "unprognostic (5.79e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (9.34e-3)" "unprognostic (3.83e-2)" "unprognostic (5.41e-2)" "unprognostic (1.76e-1)" "unprognostic (1.32e-2)" "unprognostic (2.38e-1)" 8.6 5.2 17.5 13.6 21.7 37.3 11.2 20.0 20.6 8.2 14.2 19.2 15.0 10.4 16.0 6.3 10.7 8.6 9.9 5.1 18.1 12.4 5.5 8.5 7.4 22.4 23.7 9.5 12.6 13.1 7.5 10.3 10.7 15.5 10.0 15.7 7.2 9.2 9.2 11.5 10.1 10.3 11.7 23.5 10.7 7.8 14.9 22.3 7.5 9.4 4.1 28.2 10.3 10.0 7.3 5.7 1.9 5.7 7.6 9.0 6.0 24.5 28.4 31.3 23.6 3.0 4.0 16.0 14.9 18.1 41.7 44.5 21.6 25.9 41.6 14.3 10.6 19.4 45.9 21.7 35.3 21.3 39.3 26.5 15.9 14.9 1.6 44.9 17.2 2.8 4.1 30.6 18.4 15.8 50.6 34.1 21.1 52.4 76.3 18.4 27.4 20.5 41.1 45.9 50.7 8.1 14.9 20.5 31.2 23.6 21.9 7.4 10.1 18.8 6.7 15.8 28.6 30.8 29.6 14.3 24.3 74.8 10.9 36.1 28.1 1.8 2.5 1.9 8.1 4.1 6.2 5.3 5.7 7.9 5.5 7.3 5.9 5.7 1.6 7.6 5.7 5.7 9.0 6.0 17.5 21.7 20.0 20.6 18.1 12.4 23.7 9.5 15.5 22.3 MCM8 "C20orf154, dJ967N21.5, MGC119522, MGC119523, MGC12866, MGC4816, REC" ENSG00000125885 "Minichromosome maintenance 8 homologous recombination repair factor" Q9UJA3 20 5950652-5998977 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Disease mutation, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045141, HPA066433" Supported Nucleoplasm Nucleoplasm "HPA045141: , HPA066433: " "unprognostic (6.55e-2)" "unprognostic (2.46e-2)" "unprognostic (4.43e-1)" "unprognostic (2.22e-3)" "unprognostic (1.90e-1)" "unprognostic (5.78e-2)" "prognostic unfavourable (9.30e-8)" "unprognostic (5.21e-2)" "unprognostic (5.14e-2)" "unprognostic (2.50e-1)" "prognostic unfavourable (7.50e-4)" "unprognostic (6.74e-2)" "unprognostic (1.11e-2)" "unprognostic (5.53e-2)" "unprognostic (2.76e-1)" "unprognostic (2.66e-2)" "unprognostic (3.47e-1)" 4.9 5.4 7.3 11.0 7.6 11.2 9.3 17.9 12.7 5.4 6.2 3.1 12.0 5.4 5.9 3.9 6.6 4.3 2.7 11.3 4.8 2.2 4.3 3.1 6.3 9.6 10.6 5.1 5.0 5.6 5.1 4.8 5.4 7.1 5.9 6.0 3.5 5.1 7.2 11.2 6.1 6.1 7.0 8.3 6.1 5.6 21.9 7.7 8.8 4.4 7.0 9.5 6.0 6.1 1.8 1.7 3.3 0.7 1.9 3.0 0.4 18.9 14.8 12.8 12.9 3.4 4.1 11.3 15.6 6.3 12.2 14.7 16.2 12.0 19.4 4.7 5.2 20.4 21.2 12.3 22.1 5.3 8.7 21.4 7.1 15.7 0.5 22.5 3.3 1.9 2.0 20.6 8.5 5.7 21.8 19.1 12.5 5.3 11.6 11.8 17.1 8.7 14.2 21.7 7.8 3.1 7.6 9.5 10.1 15.9 17.7 9.5 11.4 8.0 3.8 21.7 18.1 11.7 22.6 8.2 20.5 32.9 4.4 14.6 17.8 3.3 0.5 1.7 1.8 0.5 3.0 1.8 1.1 2.1 0.1 1.7 1.1 1.7 2.1 1.9 0.7 1.7 2.0 0.4 7.3 7.6 17.9 12.7 4.8 2.2 10.6 5.1 7.1 7.7 MCM9 "C6orf61, dJ329L24.3, FLJ20170, MCMDC1, MGC35304" ENSG00000111877 "Minichromosome maintenance 9 homologous recombination repair factor" Q9NXL9 6 118813442-118935162 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031137 Approved Approved Nucleoplasm Nucleoplasm "HPA031137: AB_10602027" "unprognostic (3.11e-2)" "unprognostic (1.99e-1)" "unprognostic (4.33e-3)" "unprognostic (2.90e-1)" "unprognostic (2.78e-2)" "unprognostic (2.82e-1)" "unprognostic (3.00e-2)" "unprognostic (2.29e-1)" "unprognostic (3.61e-2)" "unprognostic (7.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (8.30e-2)" "unprognostic (2.16e-1)" "unprognostic (3.95e-1)" "unprognostic (2.26e-1)" "unprognostic (8.79e-2)" 8.6 7.2 5.9 11.9 8.4 14.5 17.7 5.2 6.9 9.4 11.2 8.2 9.8 7.3 9.0 16.0 10.2 8.6 8.2 6.6 5.9 4.0 9.3 7.6 15.6 12.1 11.5 4.7 8.7 12.2 11.9 11.2 13.8 6.3 10.5 8.4 7.0 11.8 8.7 4.2 9.8 12.6 10.9 5.7 10.2 7.3 7.9 8.1 27.0 13.1 7.1 9.9 9.6 10.5 3.1 5.2 8.0 5.3 10.2 6.4 3.9 4.6 7.4 11.8 12.7 5.3 5.3 9.1 4.4 7.8 6.5 8.3 6.0 8.3 14.0 5.5 7.5 14.0 8.2 4.7 9.1 8.2 11.3 11.1 8.7 5.9 3.1 11.9 7.5 5.8 5.6 6.6 7.7 6.2 13.4 6.5 4.2 9.7 10.5 9.6 5.8 3.3 8.4 7.4 3.7 6.6 9.3 10.2 7.4 7.7 5.7 4.0 8.4 16.9 6.3 5.1 4.6 3.6 6.4 8.6 7.2 16.6 6.6 9.8 6.0 7.2 4.5 8.0 4.9 5.3 3.8 3.1 3.0 5.0 5.2 3.0 3.6 3.5 5.4 10.2 3.2 3.7 6.4 3.9 5.9 8.4 5.2 6.9 5.9 4.0 11.5 4.7 6.3 8.1 MDH1 ENSG00000014641 "Malate dehydrogenase 1" P40925 2 63588609-63607197 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 155.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027296, CAB047333, HPA054276" Uncertain Supported Centrosome,Cytosol 63000000 "Centrosome, Cytosol" "CAB047333: , HPA027296: AB_10611118, HPA054276: " "unprognostic (1.01e-1)" "unprognostic (6.52e-3)" "unprognostic (1.61e-2)" "prognostic unfavourable (7.13e-4)" "unprognostic (1.83e-1)" "unprognostic (8.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.79e-2)" "unprognostic (9.52e-2)" "unprognostic (2.05e-1)" "unprognostic (3.26e-1)" "unprognostic (8.80e-2)" "prognostic favourable (9.95e-4)" "unprognostic (6.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.97e-2)" "unprognostic (3.05e-1)" 32.0 28.6 28.0 10.5 58.1 9.2 18.4 38.0 69.5 12.4 21.4 12.5 9.0 19.3 13.4 22.6 16.7 14.7 11.5 155.8 33.6 37.5 47.6 33.2 11.2 14.7 33.4 40.1 10.9 8.9 26.0 18.3 11.4 65.9 16.1 24.9 13.8 15.4 19.9 91.1 11.1 17.1 21.5 18.6 9.4 22.4 8.6 12.2 14.1 15.6 47.1 20.2 15.6 10.2 61.7 57.1 50.7 61.5 46.7 74.5 67.8 44.0 36.1 48.8 31.9 69.4 51.4 50.6 34.7 51.3 52.9 53.7 42.7 39.1 55.5 20.6 45.4 38.8 54.9 64.3 75.9 33.6 42.4 52.1 33.8 67.8 38.1 59.9 41.3 50.9 43.9 49.5 29.3 40.3 28.8 40.4 69.5 26.5 52.4 60.5 28.6 45.0 41.9 57.5 54.4 87.5 41.8 45.3 27.0 29.1 46.9 66.5 34.2 62.5 23.4 40.6 39.8 33.7 43.6 50.4 44.2 67.9 50.1 54.2 33.5 50.7 45.8 45.8 52.7 61.5 55.0 61.7 61.3 57.6 57.1 56.4 60.5 57.5 7.0 46.7 55.7 43.3 74.5 67.8 28.0 58.1 38.0 69.5 33.6 37.5 33.4 40.1 65.9 12.2 MDH2 ENSG00000146701 "Malate dehydrogenase 2" P40926 7 76048051-76067508 "Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 175.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019714, HPA019716, HPA019848, HPA026720" Enhanced Enhanced Mitochondria 47000000 Mitochondria "HPA019714: AB_1853678, HPA019716: AB_1853680, HPA019848: AB_1853683, HPA026720: AB_1853685" "unprognostic (3.20e-2)" "unprognostic (2.85e-1)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (5.55e-3)" "unprognostic (8.94e-2)" "unprognostic (6.45e-2)" "unprognostic (3.77e-2)" "unprognostic (3.60e-1)" "unprognostic (2.02e-2)" "unprognostic (1.40e-1)" "unprognostic (9.70e-2)" "prognostic favourable (1.49e-5)" "unprognostic (8.57e-2)" "unprognostic (9.64e-2)" "unprognostic (5.68e-2)" "unprognostic (2.66e-1)" 18.1 39.1 17.4 15.4 20.6 18.3 22.2 15.3 34.4 14.9 27.0 13.5 16.9 32.5 16.6 13.5 31.8 19.4 17.6 103.1 17.1 18.8 29.1 101.9 13.8 26.6 17.4 21.9 17.3 35.5 16.8 16.9 17.5 20.5 17.9 24.3 15.0 26.8 21.5 175.8 24.6 26.7 21.9 12.8 21.1 22.3 17.6 9.5 22.4 20.1 76.2 23.8 19.9 17.8 37.1 52.8 22.1 45.3 30.1 45.6 44.7 28.6 47.0 17.0 42.6 19.5 21.4 29.3 19.3 24.9 27.6 25.0 41.3 34.5 43.4 8.7 25.4 29.3 43.7 28.8 19.8 30.9 63.2 24.1 25.3 38.1 24.0 37.4 24.9 27.0 25.7 26.8 40.1 25.7 75.8 25.4 25.5 64.9 32.4 66.1 37.9 59.3 26.5 21.0 62.4 25.8 37.9 42.7 38.9 19.3 96.8 39.7 55.0 42.3 19.8 27.8 26.3 30.0 38.3 28.5 23.5 48.0 24.1 48.0 42.1 22.1 38.9 18.2 32.7 43.5 34.2 37.1 36.9 35.3 52.8 32.1 36.0 33.1 10.2 30.1 45.3 47.1 45.6 44.7 17.4 20.6 15.3 34.4 17.1 18.8 17.4 21.9 20.5 9.5 MDM2 "HDM2, MGC5370" ENSG00000135679 "MDM2 proto-oncogene" Q00987 12 68808176-68850686 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 93.7;U-698: 90.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000086, CAB016303" Supported Supported Nucleoplasm Nucleoplasm "CAB000086: AB_563872, CAB016303: AB_627920" "unprognostic (1.16e-1)" "prognostic favourable (3.23e-4)" "unprognostic (6.16e-2)" "prognostic favourable (4.51e-7)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.77e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (3.23e-1)" "unprognostic (1.80e-3)" "unprognostic (2.36e-1)" "unprognostic (4.22e-2)" "unprognostic (4.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (8.95e-2)" 16.6 15.3 11.1 12.5 10.8 23.1 12.5 12.0 11.3 13.1 16.6 13.6 11.9 5.2 8.8 9.4 14.2 12.6 12.3 9.0 8.8 8.6 11.2 25.7 15.9 13.3 14.2 7.1 11.0 21.4 11.4 10.4 24.5 11.9 12.6 21.5 7.8 10.5 11.1 19.5 9.8 7.2 10.8 10.8 15.3 9.8 6.5 11.5 29.5 13.6 10.8 14.1 13.5 12.6 4.9 4.0 19.3 6.4 3.6 4.4 3.0 3.1 7.3 7.7 3.9 10.0 9.3 39.4 8.7 8.7 4.6 7.4 4.4 1.4 32.6 2.4 5.7 1.8 5.2 93.7 7.5 8.6 3.7 6.0 6.2 19.8 9.8 5.3 5.5 14.3 8.0 18.4 12.5 12.9 6.1 7.9 8.8 5.0 7.0 1.7 6.5 1.4 24.8 5.3 2.7 2.8 26.1 5.9 3.4 5.5 4.3 1.9 10.1 3.5 13.8 3.5 6.7 2.9 3.1 12.1 7.6 90.1 5.4 2.1 14.4 5.3 5.4 4.8 4.4 4.0 3.9 4.7 3.7 4.1 2.8 4.9 4.0 3.7 19.3 3.6 6.4 4.0 3.8 3.0 11.1 10.8 12.0 11.3 8.8 8.6 14.2 7.1 11.9 11.5 MDP1 "FN6Pase, MGC5987" ENSG00000213920 "Magnesium dependent phosphatase 1" Q86V88 14 24213937-24216070 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003064, HPA070338" Uncertain Approved Nucleoplasm 34000 Nucleoplasm "HPA003064: AB_10602350, HPA070338: " "unprognostic (2.70e-1)" "unprognostic (3.68e-1)" "unprognostic (2.51e-1)" "unprognostic (2.11e-1)" "unprognostic (3.09e-1)" "unprognostic (5.46e-2)" "unprognostic (5.48e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "unprognostic (8.02e-2)" "unprognostic (2.00e-3)" "unprognostic (1.02e-1)" "prognostic favourable (5.96e-4)" "unprognostic (6.39e-2)" "unprognostic (1.32e-1)" "unprognostic (3.82e-1)" "unprognostic (3.19e-2)" 12.2 17.6 18.5 8.3 15.0 8.1 18.7 18.6 18.3 13.3 10.2 13.1 21.0 6.7 10.6 19.0 8.9 14.3 12.0 17.8 13.8 13.9 16.6 14.7 8.7 13.5 15.1 14.5 12.9 20.2 14.8 18.3 9.4 16.6 13.3 8.6 13.5 14.3 16.3 11.4 10.6 9.8 10.9 13.9 10.4 10.0 6.6 17.0 14.3 14.6 10.6 10.8 10.0 9.6 10.1 23.0 12.2 11.1 9.0 11.9 7.9 3.1 7.8 5.9 3.8 5.9 5.5 0.2 3.4 7.4 6.9 7.1 4.1 9.0 12.6 8.7 3.5 3.0 2.9 6.8 4.3 4.2 3.2 4.8 2.9 9.5 5.7 6.2 3.5 3.9 6.2 4.1 7.9 4.8 1.5 9.5 6.1 17.0 8.7 10.1 1.6 14.1 6.3 4.2 10.0 6.6 4.6 7.3 7.1 5.4 11.5 7.2 6.9 3.2 2.9 7.5 7.2 3.1 3.4 15.4 6.1 9.2 7.0 3.1 5.7 3.1 10.9 12.2 6.3 11.1 5.9 10.1 8.1 7.3 12.4 9.5 9.9 8.2 3.8 9.0 9.4 23.0 11.9 7.9 18.5 15.0 18.6 18.3 13.8 13.9 15.1 14.5 16.6 17.0 ME1 ENSG00000065833 "Malic enzyme 1" P48163 6 83210389-83431071 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 8 "MAIT T-cell: 15.6" "Lineage enriched" "Detected in many" 11 "T-cells: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006493 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" 3800000 "Nucleoplasm, Plasma membrane" Cytosol "HPA006493: AB_1078272" "unprognostic (7.21e-2)" "unprognostic (3.99e-2)" "unprognostic (2.24e-1)" "unprognostic (3.12e-3)" "prognostic unfavourable (7.73e-4)" "unprognostic (7.98e-3)" "prognostic unfavourable (4.57e-5)" "unprognostic (3.24e-1)" "unprognostic (4.44e-3)" "unprognostic (1.41e-3)" "unprognostic (7.10e-3)" "unprognostic (2.43e-1)" "prognostic unfavourable (1.81e-7)" "unprognostic (4.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-2)" "unprognostic (4.51e-2)" 30.7 35.3 16.3 4.6 17.7 0.8 27.1 5.5 13.1 5.9 6.7 5.4 39.2 18.1 3.8 7.4 24.5 4.2 13.5 21.3 10.5 14.0 3.6 12.4 7.7 6.0 16.8 11.8 10.0 3.3 30.0 11.1 2.9 16.3 7.9 10.1 9.3 7.8 30.2 25.7 10.1 8.7 18.7 17.2 6.3 20.0 13.4 7.2 1.4 6.3 20.9 4.5 13.7 14.9 0.0 0.0 0.0 1.4 0.0 15.6 0.5 9.5 19.8 0.4 0.0 16.9 15.8 0.0 6.2 15.9 6.6 12.9 46.4 8.4 0.0 16.2 14.5 10.1 14.7 5.5 7.3 0.0 8.3 0.0 12.7 0.0 21.7 4.6 17.4 17.2 11.1 13.3 9.1 10.3 6.6 0.0 8.9 10.7 0.0 5.3 0.0 7.8 0.0 16.7 9.2 19.6 4.6 2.0 5.1 10.5 15.6 0.3 0.0 11.4 10.9 4.1 4.9 1.3 0.0 3.7 4.2 0.0 0.0 0.0 12.1 0.0 1.4 0.0 0.8 0.3 15.6 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 16.3 17.7 5.5 13.1 10.5 14.0 16.8 11.8 16.3 7.2 ME2 ENSG00000082212 "Malic enzyme 2" P23368 18 50878734-50954257 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008247, HPA008880" Enhanced Supported Mitochondria 3400000 Mitochondria "HPA008247: AB_1853704, HPA008880: AB_1853702" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (9.57e-3)" "unprognostic (2.22e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "prognostic unfavourable (8.29e-8)" "unprognostic (1.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-2)" "unprognostic (4.75e-2)" "unprognostic (1.43e-2)" "unprognostic (4.27e-3)" "unprognostic (2.30e-1)" "unprognostic (2.47e-1)" "unprognostic (4.09e-1)" 12.6 18.1 17.1 18.4 16.2 11.6 10.7 13.2 16.0 9.4 26.4 14.3 16.8 30.2 10.5 7.7 10.6 9.3 10.5 34.6 15.8 17.8 12.1 12.1 10.3 24.1 18.7 14.0 11.1 16.7 20.6 20.2 10.5 47.7 11.8 26.6 9.4 8.8 23.1 29.5 7.1 44.8 16.9 18.9 36.6 20.3 15.3 8.7 24.3 9.0 7.8 17.3 14.2 15.7 4.9 9.6 14.3 17.4 6.7 6.0 4.5 12.9 13.0 17.4 20.2 7.9 8.8 8.0 10.8 8.1 14.2 12.0 5.9 7.1 46.2 4.3 9.6 10.8 25.8 10.9 16.3 19.1 4.0 11.8 8.2 6.9 23.4 39.2 14.2 5.4 13.5 17.8 29.0 18.1 12.5 11.3 9.6 2.7 28.3 3.9 11.6 5.3 18.6 8.6 13.3 15.4 2.8 21.5 11.4 10.1 6.2 10.8 4.7 19.0 11.1 10.1 11.3 5.2 14.3 21.1 8.5 22.7 10.2 28.0 10.7 5.0 11.6 14.3 5.0 13.1 4.1 4.9 3.3 6.0 9.6 4.9 2.9 3.5 13.3 6.7 17.4 3.2 3.1 4.5 17.1 16.2 13.2 16.0 15.8 17.8 18.7 14.0 47.7 8.7 ME3 ENSG00000151376 "Malic enzyme 3" Q16798 11 86441108-86672636 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 26.9;HUVEC TERT2: 17.9;TIME: 19.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 5.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038473 Approved "HPA038473: AB_10672747" "unprognostic (1.83e-3)" "unprognostic (8.00e-2)" "unprognostic (1.99e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-1)" "unprognostic (2.91e-1)" "unprognostic (5.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-1)" "unprognostic (1.20e-1)" "unprognostic (5.74e-2)" "unprognostic (2.97e-1)" "unprognostic (1.65e-1)" "unprognostic (2.73e-1)" "unprognostic (2.96e-2)" "prognostic favourable (3.86e-4)" 17.2 15.9 16.0 6.3 27.7 5.8 13.1 15.7 26.1 19.3 14.3 4.8 7.3 7.8 15.8 7.6 5.0 9.0 12.9 21.9 12.2 13.1 12.6 3.9 8.1 4.3 12.5 18.1 22.1 16.7 28.5 15.4 5.4 20.2 13.0 15.0 11.5 13.6 10.3 21.2 3.0 7.1 15.6 5.5 7.3 20.8 8.8 8.4 2.8 8.2 6.3 2.9 10.3 10.2 0.0 5.0 0.0 0.9 2.2 3.1 1.0 0.0 9.0 2.5 0.0 4.1 8.5 0.0 3.1 4.7 6.4 8.1 6.8 26.9 0.0 2.7 2.8 0.1 0.0 0.0 2.9 4.7 0.0 4.6 7.4 0.0 6.1 0.5 0.0 5.9 1.4 5.1 0.0 17.9 0.1 0.0 4.2 0.9 1.2 0.0 0.6 3.7 3.9 0.0 0.3 5.7 10.5 3.1 0.0 1.9 0.0 0.0 0.4 0.7 19.8 0.8 0.6 13.3 0.4 0.0 1.6 0.0 0.7 8.3 0.8 0.0 0.9 0.0 1.9 0.1 0.0 0.0 1.9 3.1 5.0 0.0 2.3 2.7 0.0 2.2 0.3 0.6 0.0 1.0 16.0 27.7 15.7 26.1 12.2 13.1 12.5 18.1 20.2 8.4 MECR "CGI-63, ETR1, FASN2B, NRBF1" ENSG00000116353 "Mitochondrial trans-2-enoyl-CoA reductase" Q9BV79 1 29192873-29230942 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease mutation, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA022018, HPA022030, HPA028740" Enhanced Supported Mitochondria Mitochondria "HPA022018: AB_1853714, HPA022030: AB_1853716, HPA028740: AB_10601133" "unprognostic (2.53e-1)" "unprognostic (1.09e-2)" "unprognostic (1.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.07e-1)" "unprognostic (2.46e-1)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.06e-2)" "unprognostic (8.66e-2)" "prognostic favourable (5.81e-6)" "unprognostic (7.01e-3)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "prognostic unfavourable (5.29e-4)" 16.4 11.9 16.0 6.6 17.0 6.0 12.3 7.8 17.7 13.0 9.7 8.6 7.1 7.8 10.5 8.4 9.4 10.9 8.5 24.8 15.7 11.5 11.0 13.7 8.3 10.0 14.7 16.3 11.7 14.3 8.1 10.0 10.8 12.8 7.5 8.9 10.8 12.6 10.0 45.5 11.3 5.9 10.2 10.7 5.4 8.1 8.2 10.5 4.4 8.3 12.8 7.6 8.0 7.2 8.3 14.7 0.3 11.5 11.6 13.1 6.5 10.3 9.9 4.8 22.5 4.9 8.8 17.8 7.8 8.9 10.3 10.0 7.5 21.2 13.6 15.8 7.7 12.9 6.1 16.0 6.4 9.3 12.6 11.8 6.3 9.5 15.4 13.0 6.0 8.7 14.2 5.4 20.1 11.3 10.1 14.1 12.8 11.6 11.0 7.2 13.0 12.7 6.8 8.2 24.0 10.9 6.0 7.4 11.4 11.6 16.5 14.5 6.1 12.6 11.4 7.5 8.1 11.7 11.6 13.5 5.6 10.2 20.2 17.4 14.1 0.1 7.0 0.0 8.3 11.5 13.1 8.3 7.8 6.7 14.7 7.4 8.4 8.5 0.3 11.6 7.0 8.6 6.3 6.5 16.0 17.0 7.8 17.7 15.7 11.5 14.7 16.3 12.8 10.5 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "T-reg: 4.8" "Lineage enriched" "Detected in many" 5 "T-cells: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA017214 Uncertain "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavourable (2.91e-7)" "prognostic unfavourable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavourable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 1.5 1.1 0.3 11.4 0.6 7.7 2.6 0.2 0.8 2.1 5.9 0.3 0.1 4.5 1.2 1.5 12.2 0.4 1.6 1.3 0.5 0.4 1.2 1.3 2.0 8.3 0.4 0.1 0.7 0.8 0.0 0.3 6.3 0.5 0.7 7.8 0.4 2.3 0.1 0.9 2.8 4.6 1.9 1.0 5.2 2.9 11.3 0.4 42.4 0.5 7.2 12.6 1.5 3.3 0.1 0.6 1.0 0.1 0.4 4.8 0.5 35.4 18.2 24.6 14.5 3.4 5.9 14.3 26.3 18.6 36.9 45.6 14.0 14.0 11.9 8.5 12.9 12.2 21.4 16.5 40.8 32.3 8.5 9.3 21.7 13.9 1.3 14.4 11.8 2.1 3.0 28.5 16.2 18.6 11.9 19.0 30.2 11.8 17.9 6.8 19.6 14.3 16.6 16.6 7.6 11.3 12.0 16.7 12.4 14.0 13.5 8.5 11.3 6.9 9.1 19.9 25.2 16.8 23.9 3.7 13.5 17.8 12.6 10.7 27.0 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.6 4.8 0.5 0.3 0.6 0.2 0.8 0.5 0.4 0.4 0.1 0.5 0.4 MEP1A PPHA ENSG00000112818 "Meprin A subunit alpha" Q16819 6 46793390-46839782 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 52 "intestine: 243.0" "Cell line enhanced" "Detected in some" "BEWO: 3.0;CACO-2: 6.9;Hep G2: 1.8;NB-4: 3.0;RPMI-8226: 3.4;SH-SY5Y: 2.1;U-2197: 2.0" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 38.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "myeloid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025163, HPA029416" Enhanced 990000 "CAB025163: , HPA029416: AB_10600823" "unprognostic (1.83e-1)" "unprognostic (2.81e-4)" "unprognostic (2.03e-1)" "unprognostic (8.53e-2)" "unprognostic (8.73e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-2)" "unprognostic (5.27e-4)" "unprognostic (2.05e-1)" "unprognostic (2.35e-2)" "unprognostic (1.42e-1)" "unprognostic (2.11e-1)" "unprognostic (1.11e-3)" "unprognostic (1.45e-1)" "unprognostic (1.91e-2)" "unprognostic (4.70e-3)" "unprognostic (1.68e-1)" 0.1 0.1 0.1 4.7 0.1 0.0 0.1 0.1 0.1 0.1 100.5 0.1 0.1 51.7 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.0 0.1 0.1 0.1 0.1 19.8 0.1 0.2 0.1 0.1 0.1 243.0 0.2 0.2 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 MEP1B ENSG00000141434 "Meprin A subunit beta" Q16820 18 32185069-32220404 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "intestine: 241.5" "Cell line enhanced" "Detected in some" "SCLC-21H: 10.3" "Group enriched" "Detected in some" 5 "pancreatic cancer: 3.0;stomach cancer: 0.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029119 Enhanced "Secreted to digestive system" 120000 "HPA029119: " "unprognostic (1.33e-1)" "unprognostic (6.72e-2)" "unprognostic (2.79e-2)" "unprognostic (1.00e-1)" "unprognostic (3.50e-4)" "unprognostic (1.27e-1)" "unprognostic (1.74e-2)" "unprognostic (4.30e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (8.31e-4)" "unprognostic (4.74e-2)" "unprognostic (3.39e-1)" "unprognostic (2.71e-1)" "unprognostic (3.39e-2)" "unprognostic (3.75e-2)" 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 0.1 78.8 0.0 0.0 54.5 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 1.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.1 241.5 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.1 0.4 0.3 0.3 0.0 1.4 0.5 0.2 0.0 0.0 0.5 0.6 0.0 2.0 1.0 0.3 0.2 0.1 0.5 1.4 1.7 0.5 0.0 0.2 0.0 0.0 0.0 0.7 0.9 1.1 0.7 0.6 0.4 1.3 0.3 0.0 0.7 0.0 0.1 0.4 1.1 0.2 0.0 1.9 1.3 4.0 1.3 0.0 1.8 1.7 2.9 0.0 0.7 10.3 2.3 0.8 0.2 0.3 0.4 3.0 0.9 1.3 0.8 3.4 0.0 0.5 2.2 0.5 2.6 0.0 0.5 0.0 0.3 0.3 1.0 0.1 1.3 1.1 0.7 1.4 0.4 0.1 1.2 0.3 0.2 0.0 0.1 0.2 0.5 0.5 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.0 0.0 MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898479-112029561 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 20.8;Hep G2: 21.6;HUVEC TERT2: 21.5;RT4: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 10.3;non-classical monocyte: 6.4" "Lineage enriched" "Detected in single" 48 "monocytes: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Approved Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" 29000000 "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: " "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favourable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favourable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" 20.1 55.1 13.1 12.5 17.8 1.9 31.8 6.2 13.8 10.8 13.8 6.8 27.7 11.5 11.3 25.4 8.4 12.8 11.7 7.1 16.5 6.3 14.2 18.9 12.7 30.3 8.1 10.1 12.9 9.0 23.9 14.3 18.4 18.6 14.1 7.9 20.4 6.8 24.9 6.4 6.4 12.8 13.6 12.2 38.4 12.3 17.3 9.8 1.7 9.9 2.0 8.4 14.1 26.6 0.0 0.2 0.1 10.3 0.0 0.0 0.3 0.5 0.9 4.3 9.7 0.2 0.1 6.9 0.0 0.1 0.5 1.0 20.8 1.3 0.1 4.6 0.0 0.1 5.7 0.0 0.8 0.8 3.0 3.7 0.0 21.6 0.1 0.1 0.8 0.2 0.0 5.0 0.3 21.5 1.1 2.0 1.6 0.9 0.0 4.9 2.7 3.4 1.4 1.2 1.6 10.9 12.9 0.1 4.1 0.1 0.3 1.7 0.0 0.2 3.2 0.6 2.0 0.0 0.0 1.7 2.5 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 6.4 0.1 0.0 0.3 13.1 17.8 6.2 13.8 16.5 6.3 8.1 10.1 18.6 9.8 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672390-116798386 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease mutation, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 45.4;CAPAN-2: 49.6;EFO-21: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "amygdala: 3.5;basal ganglia: 9.9;cerebral cortex: 7.6;hippocampal formation: 8.0;olfactory region: 9.1" "Low region specificity" "Detected in many" "CAB005282, CAB018577, HPA055607" Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" 178550000 70000000 "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: " "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavourable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavourable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 16.2 1.1 1.8 4.5 2.3 4.3 11.2 0.9 15.2 9.9 6.5 2.4 2.4 4.4 7.5 5.2 5.1 4.6 12.3 5.4 5.7 1.8 20.1 30.2 15.6 1.4 3.6 2.1 2.0 9.3 0.7 8.1 24.4 2.6 8.0 6.6 34.1 12.2 8.4 12.8 7.2 8.6 4.0 2.3 5.7 10.6 2.7 2.4 0.5 21.4 7.0 2.1 10.1 15.0 0.2 0.3 1.2 0.2 0.3 0.4 0.0 45.4 26.1 0.0 0.1 2.0 2.0 1.8 26.0 10.6 14.0 11.8 5.4 49.6 2.0 43.3 16.3 12.0 4.5 24.7 28.7 0.1 5.6 0.0 27.1 4.7 0.3 0.0 0.0 2.6 9.8 9.1 30.1 9.6 0.9 0.2 25.9 1.0 0.0 0.0 3.9 26.7 0.0 22.0 0.0 24.6 5.2 3.8 0.0 10.7 3.4 10.1 0.0 0.2 17.7 20.9 7.4 11.0 20.1 0.5 4.0 0.2 23.0 0.0 2.9 1.1 0.2 0.4 0.4 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 1.2 0.3 0.1 0.3 0.1 0.0 1.8 2.3 0.9 15.2 5.7 1.8 3.6 2.1 2.6 2.4 METAP1 "KIAA0094, MAP1A, MetAP1A" ENSG00000164024 "Methionyl aminopeptidase 1" P53582 4 98995620-99062813 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025485, HPA037997, HPA037998" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" 11000 Cytosol "Nucleoplasm, Plasma membrane" "CAB025485: , HPA037997: , HPA037998: " "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "prognostic favourable (7.22e-4)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (2.15e-1)" "prognostic unfavourable (3.08e-5)" "unprognostic (1.09e-1)" "unprognostic (1.51e-3)" "unprognostic (2.05e-1)" "prognostic unfavourable (2.28e-5)" "unprognostic (2.00e-1)" "prognostic favourable (1.72e-4)" "unprognostic (5.50e-2)" "unprognostic (8.51e-2)" "unprognostic (1.15e-3)" "prognostic favourable (9.31e-4)" 12.1 8.3 10.0 16.0 10.1 11.8 18.6 9.2 13.8 16.0 17.9 7.0 22.9 13.4 24.1 25.9 37.2 14.0 12.3 27.9 9.5 7.1 14.3 13.7 10.7 12.6 7.9 9.8 11.3 13.0 7.8 14.4 9.2 9.9 19.1 19.3 7.5 19.0 21.5 27.2 16.4 15.2 27.8 10.1 13.9 11.6 46.8 8.1 27.0 10.8 21.8 19.1 36.6 22.6 12.7 11.7 10.4 11.1 12.5 19.2 10.8 21.7 21.5 18.9 20.2 15.0 24.1 21.0 31.2 20.1 26.7 25.5 24.1 32.5 32.2 12.5 25.2 21.9 33.1 31.2 37.1 22.5 15.8 28.8 15.7 25.8 16.3 38.9 24.1 17.3 22.7 22.6 24.1 21.9 22.5 19.5 28.5 16.5 34.0 18.6 23.2 17.5 22.4 29.5 17.2 42.8 28.2 25.9 15.3 10.4 32.3 12.3 12.4 14.9 17.8 21.6 27.5 19.7 27.1 14.1 19.9 25.5 18.6 19.9 21.4 10.4 9.4 4.2 14.9 11.1 19.2 12.7 15.4 14.5 11.7 10.1 15.1 13.5 2.3 12.5 10.7 5.8 13.4 10.8 10.0 10.1 9.2 13.8 9.5 7.1 7.9 9.8 9.9 8.1 METAP1D "MAP1D, Metap1l" ENSG00000172878 "Methionyl aminopeptidase type 1D, mitochondrial" Q6UB28 2 171999583-172082430 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030298, HPA030299" Uncertain Uncertain Vesicles Vesicles "HPA030298: AB_2673419, HPA030299: AB_10602421" "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (1.88e-1)" "unprognostic (5.83e-2)" "unprognostic (2.54e-2)" "unprognostic (7.90e-3)" "unprognostic (1.92e-3)" "unprognostic (1.07e-2)" "unprognostic (4.55e-1)" "unprognostic (7.07e-2)" "unprognostic (2.64e-2)" "unprognostic (8.19e-2)" "unprognostic (2.53e-3)" "unprognostic (3.44e-3)" "unprognostic (3.06e-2)" "unprognostic (5.48e-3)" "unprognostic (2.92e-2)" 7.1 7.5 7.2 8.0 8.4 6.3 8.2 6.7 9.2 6.5 6.1 9.6 6.5 5.0 9.0 6.4 5.2 10.3 4.5 6.4 6.0 4.9 5.4 8.3 3.6 8.1 9.3 7.1 18.9 23.8 5.5 13.8 4.1 8.6 8.3 7.1 7.3 9.7 10.3 13.8 7.1 5.9 10.0 7.2 8.6 6.3 5.9 9.5 2.1 5.6 6.3 6.7 5.4 5.7 2.5 0.5 0.2 1.2 1.2 3.6 0.7 3.3 2.6 3.9 13.0 5.8 7.5 8.0 3.8 3.9 6.2 3.9 6.0 4.4 1.7 7.0 4.0 6.1 8.5 6.7 6.3 5.9 10.1 9.4 6.9 7.9 6.2 5.5 2.5 5.7 10.6 6.1 9.9 3.5 13.5 4.8 4.6 4.1 3.1 7.5 7.1 3.2 7.1 3.4 3.0 4.4 4.6 8.1 3.1 2.7 5.6 9.5 6.4 7.5 4.1 7.9 6.3 4.8 3.6 6.0 5.4 3.8 5.6 11.1 7.5 0.0 0.2 0.0 1.3 1.2 0.6 1.2 1.9 0.7 0.5 2.5 1.9 3.6 0.2 1.2 0.2 0.0 1.4 0.7 7.2 8.4 6.7 9.2 6.0 4.9 9.3 7.1 8.6 9.5 METAP2 "MAP2, MNPEP, p67" ENSG00000111142 "Methionyl aminopeptidase 2" P50579 12 95473520-95515839 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013025, HPA019095" Enhanced Supported "Plasma membrane,Cytosol" 22000 "Plasma membrane, Cytosol" "CAB013025: AB_2533993, HPA019095: AB_1853823" "unprognostic (1.91e-1)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.44e-1)" "unprognostic (3.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavourable (4.51e-6)" "unprognostic (1.25e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-2)" "unprognostic (8.53e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" 24.2 36.4 25.8 49.9 33.7 39.1 25.1 25.9 32.3 23.9 26.2 16.3 102.5 16.6 28.7 25.4 30.1 22.5 21.7 30.7 29.6 24.0 26.0 46.8 22.1 32.6 29.1 23.4 29.4 31.9 21.0 36.1 25.1 42.9 24.2 24.0 10.1 22.1 140.7 94.4 28.7 19.7 26.1 48.2 25.2 22.2 26.3 27.7 32.1 24.1 29.0 55.2 33.4 37.3 39.4 31.8 21.3 27.1 25.7 32.0 16.2 33.2 28.1 30.1 23.3 18.3 29.4 23.1 32.8 23.0 32.4 23.0 40.8 16.0 97.0 20.7 23.4 21.5 33.8 25.1 37.3 23.0 29.1 43.4 21.4 28.7 19.6 53.7 21.3 25.4 26.9 30.6 30.1 34.4 56.1 11.0 24.0 21.9 39.7 36.7 36.8 42.0 31.3 26.0 31.8 22.2 35.4 23.4 30.7 29.2 23.9 28.7 28.8 25.6 29.5 18.6 18.1 20.8 34.6 15.9 41.4 104.0 10.6 30.3 23.4 21.3 27.1 11.1 23.8 19.1 29.2 39.4 26.7 26.6 24.4 37.6 32.0 29.7 1.2 25.7 22.3 31.8 25.3 16.2 25.8 33.7 25.9 32.3 29.6 24.0 29.1 23.4 42.9 27.7 METTL1 "C12orf1, TRM8, TRMT8" ENSG00000037897 "Methyltransferase like 1" Q9UBP6 12 57768471-57772793 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 6 "RH-30: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020914, HPA050450" Uncertain Supported Nucleoplasm Nucleoplasm "HPA020914: AB_1853830, HPA050450: " "unprognostic (5.24e-2)" "unprognostic (2.60e-1)" "unprognostic (9.43e-2)" "unprognostic (3.46e-1)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "prognostic unfavourable (4.25e-6)" "unprognostic (5.67e-2)" "unprognostic (6.19e-2)" "unprognostic (1.14e-3)" "unprognostic (1.78e-1)" "unprognostic (2.32e-1)" "prognostic unfavourable (3.55e-6)" "unprognostic (7.75e-2)" "unprognostic (1.96e-1)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" 12.2 16.6 6.7 13.8 8.8 8.4 12.3 2.2 6.9 7.6 7.6 4.5 10.8 3.3 9.4 21.2 10.3 9.0 10.7 8.1 5.8 5.0 20.9 15.3 7.7 8.8 7.4 4.6 17.6 34.9 10.9 10.6 8.3 6.5 11.0 10.3 5.3 17.9 17.2 20.4 8.5 5.7 10.5 5.0 8.2 7.3 11.4 5.4 4.5 15.1 15.6 9.8 8.8 7.8 6.1 12.6 0.7 6.7 7.3 18.6 5.1 5.9 11.0 4.6 4.2 6.2 4.3 6.3 6.5 5.8 10.9 5.9 7.6 8.4 7.2 12.0 7.8 7.2 7.1 10.0 10.6 4.3 8.2 8.4 4.2 9.3 4.4 9.1 4.4 3.8 9.1 12.2 8.5 5.7 7.7 7.3 5.5 11.7 6.3 10.9 10.8 11.0 5.6 77.0 10.7 9.5 7.5 4.9 4.4 6.7 7.5 6.0 9.8 8.6 4.3 4.4 4.9 7.7 8.5 3.4 2.5 8.8 6.2 6.5 9.1 0.0 4.7 0.0 5.3 6.7 18.6 4.7 6.9 6.5 10.3 6.1 9.5 9.2 0.7 7.3 1.1 12.6 3.3 5.1 6.7 8.8 2.2 6.9 5.8 5.0 7.4 4.6 6.5 5.4 METTL11B "C1orf184, HOMT1B" ENSG00000203740 "Methyltransferase like 11B" Q5VVY1 1 170146001-170167790 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "heart muscle: 7.0;skeletal muscle: 3.6" "Cell line enriched" "Detected in single" 12 "NTERA-2: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028049 Uncertain "HPA028049: AB_10610139" "unprognostic (1.12e-1)" "unprognostic (2.57e-1)" "unprognostic (5.62e-2)" "unprognostic (7.59e-2)" "unprognostic (7.25e-2)" "unprognostic (1.19e-1)" "unprognostic (8.68e-2)" "unprognostic (5.24e-2)" "unprognostic (2.76e-3)" "unprognostic (5.43e-2)" "unprognostic (4.56e-1)" "unprognostic (5.79e-4)" 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 METTL16 "METT10D, MGC3329" ENSG00000127804 "Methyltransferase like 16" Q86W50 17 2405562-2511891 "Enzymes, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020352, HPA059798" Uncertain Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA020352: AB_1853828, HPA059798: AB_2684128" "unprognostic (4.94e-3)" "unprognostic (2.86e-2)" "unprognostic (2.29e-2)" "unprognostic (5.66e-3)" "unprognostic (1.50e-1)" "unprognostic (5.47e-2)" "unprognostic (3.35e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" "unprognostic (3.46e-1)" "prognostic favourable (3.06e-4)" "unprognostic (5.35e-2)" "unprognostic (4.85e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-1)" "unprognostic (1.61e-1)" "unprognostic (2.68e-2)" 12.7 14.0 13.1 11.0 15.2 13.1 14.1 22.5 14.4 14.9 13.1 19.8 11.2 8.6 21.6 10.6 11.0 16.5 9.6 12.4 12.6 9.7 11.5 6.9 12.2 13.1 18.3 9.7 22.5 13.5 19.7 22.8 7.5 13.6 13.5 10.4 18.3 12.1 13.1 14.2 14.7 10.4 16.5 14.6 11.1 11.2 11.0 17.5 15.7 16.5 8.8 17.5 15.3 12.7 5.7 3.1 2.3 3.2 2.0 8.1 2.0 6.0 16.1 9.1 8.8 6.9 8.7 8.5 7.7 6.6 8.8 7.3 21.3 3.9 18.9 8.3 6.9 8.7 21.0 10.5 12.0 7.2 13.3 9.7 13.2 9.7 7.5 8.9 7.9 7.3 10.0 12.1 17.8 9.0 12.6 10.2 5.8 6.5 12.7 5.3 10.4 6.8 21.3 9.6 8.5 6.3 5.4 4.8 7.6 11.4 6.3 6.7 7.9 5.7 6.5 8.0 5.2 11.3 11.1 6.0 7.3 13.5 10.9 7.5 10.9 2.3 3.2 1.2 5.7 2.1 7.2 5.7 5.6 5.5 2.2 5.0 8.1 5.9 0.1 2.0 1.5 3.1 3.5 2.0 13.1 15.2 22.5 14.4 12.6 9.7 18.3 9.7 13.6 17.5 MEX3C "FLJ38871, RKHD2, RNF194" ENSG00000176624 "Mex-3 RNA binding family member C" Q5U5Q3 18 51174550-51218304 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040603 Uncertain Approved Vesicles "Intracellular and membrane" Vesicles "HPA040603: AB_10805714" "unprognostic (1.09e-1)" "unprognostic (2.90e-2)" "unprognostic (8.88e-2)" "unprognostic (8.88e-3)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "prognostic unfavourable (8.49e-5)" "unprognostic (4.34e-2)" "unprognostic (4.43e-1)" "unprognostic (1.05e-2)" "unprognostic (1.03e-2)" "unprognostic (6.75e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-1)" "unprognostic (8.01e-2)" "unprognostic (3.17e-1)" 12.6 12.2 13.8 14.5 13.5 27.5 19.4 21.7 13.7 14.7 11.3 10.7 8.8 8.7 13.4 9.5 11.7 11.1 13.0 11.3 15.1 9.1 9.3 10.3 12.0 19.8 16.3 8.3 14.5 10.1 16.6 9.5 11.7 12.3 10.3 9.8 7.6 12.4 10.1 9.0 10.2 12.7 13.6 12.6 16.3 10.5 43.7 12.7 40.0 13.6 9.3 18.4 13.0 17.5 2.8 2.0 10.3 1.3 5.8 3.8 1.5 7.5 4.5 21.8 8.1 12.1 15.0 17.0 10.8 14.1 6.3 7.7 7.2 5.8 15.4 3.8 14.3 13.8 9.4 15.4 12.1 11.3 4.2 3.3 4.5 9.4 19.6 20.9 6.3 12.6 21.7 8.8 27.6 16.2 3.5 27.0 16.2 5.5 15.6 10.4 10.5 4.5 15.8 11.4 15.8 14.5 2.5 9.7 13.3 8.1 4.4 42.5 4.4 11.7 12.1 15.2 10.1 4.6 9.2 19.6 2.9 24.6 10.4 10.6 34.3 10.3 1.3 1.5 3.6 1.3 3.1 2.8 3.8 3.7 2.0 2.1 1.6 3.8 0.7 5.8 0.9 2.0 3.1 1.5 13.8 13.5 21.7 13.7 15.1 9.1 16.3 8.3 12.3 12.7 MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486401 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 72.7;lymphoid tissue: 42.1" "Cell line enhanced" "Detected in many" "Daudi: 32.2;HL-60: 40.5;HMC-1: 53.7;HUVEC TERT2: 43.3;U-698: 31.1;U-937: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" 28000 Vesicles "HPA048936: , HPA056479: " "unprognostic (1.21e-1)" "unprognostic (4.17e-3)" "prognostic unfavourable (5.12e-4)" "prognostic favourable (1.65e-4)" "unprognostic (6.41e-3)" "unprognostic (1.00e-2)" "unprognostic (2.64e-1)" "unprognostic (2.36e-2)" "unprognostic (4.64e-2)" "unprognostic (2.91e-2)" "unprognostic (5.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavourable (3.31e-5)" "unprognostic (2.67e-1)" "unprognostic (4.03e-2)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" 10.0 4.5 2.6 16.6 5.1 14.4 13.4 1.0 3.3 6.0 6.5 3.0 2.0 3.7 6.5 3.5 4.4 7.1 6.3 6.7 2.8 2.6 6.1 5.6 14.9 42.1 5.6 1.2 3.6 3.7 0.8 2.2 14.0 8.3 5.6 3.7 4.4 5.7 2.5 3.4 3.0 14.1 5.1 4.4 37.6 4.1 2.6 3.6 33.9 6.3 4.5 19.3 8.8 4.2 24.1 40.5 72.7 40.8 40.9 53.3 53.2 1.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.6 32.2 0.1 0.0 2.3 9.4 1.8 0.0 12.7 0.2 24.8 0.1 0.3 0.1 40.5 53.7 0.0 0.5 0.3 0.7 43.3 0.1 15.3 0.0 0.1 4.6 0.5 0.1 0.1 11.9 0.4 24.2 0.1 0.0 19.4 0.1 0.1 0.0 0.0 0.2 2.8 24.1 0.0 1.2 4.8 0.1 0.0 0.1 31.1 0.2 36.4 0.5 36.8 40.1 72.7 41.3 38.8 45.1 21.8 48.0 43.3 40.5 24.1 52.9 45.5 25.5 40.9 40.8 10.1 53.3 53.2 2.6 5.1 1.0 3.3 2.8 2.6 5.6 1.2 8.3 3.6 MGAM MGA ENSG00000257335 Maltase-glucoamylase O43451 7 141907813-142106747 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 155.5" "Cell line enhanced" "Detected in some" "A549: 3.6;BJ hTERT+: 3.2;HL-60: 5.3;U-937: 8.5;WM-115: 2.0" "Cancer enriched" "Detected in some" 7 "renal cancer: 4.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "neutrophil: 14.1" "Lineage enriched" "Detected in single" 104 "granulocytes: 14.1" "Region enriched" "Detected in single" 12 "olfactory region: 3.1" HPA002270 Enhanced 68000 "HPA002270: AB_1079366" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (6.95e-3)" "unprognostic (2.80e-1)" "unprognostic (7.81e-2)" "unprognostic (7.32e-3)" "unprognostic (3.83e-2)" "unprognostic (4.97e-1)" "unprognostic (2.17e-2)" "unprognostic (6.86e-2)" "unprognostic (1.99e-1)" "prognostic favourable (6.16e-5)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.34e-3)" "unprognostic (3.03e-1)" 0.9 0.2 0.3 0.8 0.2 6.9 0.3 0.2 0.2 0.2 59.4 0.1 7.6 25.2 0.2 36.0 0.2 1.0 0.1 0.3 0.2 0.2 8.7 0.4 2.1 0.1 0.3 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.6 0.0 0.1 0.2 3.2 0.2 0.1 155.5 0.1 0.3 8.3 0.7 4.3 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 14.1 0.1 0.0 0.0 0.0 0.0 3.6 0.2 0.1 0.0 0.0 0.4 0.1 3.2 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.3 1.0 0.4 0.1 0.3 0.0 0.1 0.0 8.5 2.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.1 0.1 MGAM2 ENSG00000257743 "Maltase-glucoamylase 2 (putative)" Q2M2H8 7 142111749-142222324 "Enzymes, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 61.2;pancreas: 15.6;salivary gland: 35.4" "Cell line enriched" "Detected in single" 7 "RH-30: 5.0" "Group enriched" "Detected in some" 11 "colorectal cancer: 3.5;pancreatic cancer: 2.5;stomach cancer: 9.8" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 12 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.1" "Low region specificity" "Detected in all" HPA055697 Enhanced Approved Vesicles,Cytosol Vesicles Cytosol "HPA055697: " "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-3)" "unprognostic (5.65e-2)" "unprognostic (2.19e-2)" "unprognostic (1.89e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-2)" "unprognostic (5.93e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-1)" "unprognostic (5.50e-4)" "unprognostic (7.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.71e-2)" "unprognostic (9.33e-2)" 0.2 0.1 0.1 2.5 0.1 0.2 1.3 0.1 0.1 0.1 28.8 0.0 0.0 15.0 0.1 0.4 0.1 0.3 7.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.4 0.0 0.1 15.6 0.0 0.1 0.0 0.1 0.1 1.4 0.7 35.4 0.0 0.1 0.2 61.2 0.0 0.5 1.5 0.7 1.0 0.0 0.0 0.1 1.7 0.8 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.1 0.0 MGAT1 "GLCNAC-TI, GLYT1, GNT-1, GnTI, MGAT" ENSG00000131446 "Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase" P26572 5 180784782-180815652 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017432 Approved 7200000 "HPA017432: AB_1853851" "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (3.38e-2)" "unprognostic (2.11e-1)" "unprognostic (3.91e-2)" "unprognostic (6.70e-2)" "unprognostic (4.39e-2)" "unprognostic (9.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.98e-1)" "unprognostic (3.70e-3)" "unprognostic (6.44e-2)" "prognostic unfavourable (8.65e-4)" "unprognostic (4.15e-2)" "unprognostic (3.52e-2)" "unprognostic (5.68e-2)" "unprognostic (5.00e-2)" 67.7 20.9 14.9 30.8 20.1 25.5 53.3 15.6 19.3 22.3 29.0 14.6 22.4 24.8 26.1 26.8 31.2 26.4 19.8 26.4 16.1 10.6 20.8 55.6 42.7 50.5 25.6 10.3 27.2 37.1 8.5 20.8 84.9 17.7 26.6 15.3 24.1 28.4 21.8 18.5 22.9 35.1 20.7 31.1 45.7 24.5 19.2 21.9 27.0 32.1 16.9 29.8 38.2 39.1 13.2 40.8 37.7 54.9 16.5 24.9 47.2 14.1 14.2 7.8 16.7 41.5 18.9 27.4 33.8 41.6 21.2 26.5 20.3 11.7 12.1 19.0 32.6 17.0 4.2 50.4 12.6 65.1 11.7 10.6 8.2 15.7 20.2 9.7 34.9 21.9 24.2 17.1 17.1 18.3 6.1 21.8 18.9 20.1 9.1 13.9 7.6 18.4 11.1 11.5 15.9 8.1 16.9 6.7 8.1 14.1 14.6 27.9 11.2 17.4 19.6 25.9 11.6 11.0 15.2 41.3 34.1 10.6 21.1 19.7 13.0 19.5 54.9 25.3 22.4 45.9 24.9 13.2 16.4 18.7 40.8 12.1 14.4 16.0 37.7 16.5 35.1 38.9 18.8 47.2 14.9 20.1 15.6 19.3 16.1 10.6 25.6 10.3 17.7 21.9 MGAT2 GNT-II ENSG00000168282 "Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase" Q10469 14 49620795-49623481 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043721, HPA056824" Approved Supported "Golgi apparatus" 5000000 "Golgi apparatus" "HPA043721: , HPA056824: " "unprognostic (1.20e-2)" "prognostic unfavourable (3.22e-4)" "unprognostic (2.84e-1)" "unprognostic (5.49e-2)" "unprognostic (1.37e-1)" "unprognostic (1.70e-1)" "unprognostic (3.77e-1)" "unprognostic (1.92e-2)" "unprognostic (1.14e-1)" "unprognostic (7.44e-2)" "unprognostic (7.12e-2)" "unprognostic (5.63e-2)" "unprognostic (2.59e-3)" "unprognostic (9.14e-2)" "unprognostic (3.74e-2)" "unprognostic (4.72e-2)" "unprognostic (2.12e-2)" 14.0 17.0 7.4 14.0 7.1 5.0 12.3 7.3 8.4 11.7 16.5 7.8 16.5 13.9 12.9 14.1 11.7 11.4 16.8 10.1 6.2 6.6 13.2 34.4 10.3 20.5 6.1 7.2 15.3 27.9 4.8 8.2 14.1 5.8 9.4 13.7 10.7 34.9 19.1 5.1 6.3 29.1 9.7 7.1 20.9 12.3 27.7 5.8 18.2 9.0 7.2 14.8 11.6 9.1 15.5 28.2 22.1 22.8 12.0 24.7 23.2 18.7 9.3 7.1 12.0 17.0 16.5 4.6 20.8 20.7 19.3 17.5 11.2 14.3 19.0 17.8 18.9 15.0 10.0 12.0 20.9 19.4 8.9 12.1 6.9 11.0 13.4 27.8 28.4 12.6 9.7 11.4 16.2 23.1 9.2 52.6 20.3 7.1 9.6 17.8 7.3 15.0 10.9 20.8 16.4 15.1 10.9 7.4 8.0 14.9 3.9 11.7 12.0 19.0 23.9 17.6 19.1 12.7 14.8 56.9 27.3 17.0 8.5 13.9 11.8 21.7 22.8 22.1 23.0 20.0 24.7 15.5 21.3 20.7 23.6 10.4 12.6 17.3 6.8 12.0 21.6 28.2 18.2 23.2 7.4 7.1 7.3 8.4 6.2 6.6 6.1 7.2 5.8 5.8 MGAT3 GNT-III ENSG00000128268 "Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase" Q09327 22 39457344-39492194 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.0;intestine: 27.1" "Cell line enhanced" "Detected in some" "BEWO: 28.7;HMC-1: 24.8;U-266/70: 32.2;U-266/84: 13.0;U-698: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.5;eosinophil: 3.3;memory B-cell: 1.7;naive B-cell: 1.2" "Group enriched" "Detected in many" 9 "B-cells: 1.7;granulocytes: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017598 Approved "Intracellular and membrane" 78000 "HPA017598: AB_1853853" "unprognostic (1.41e-3)" "unprognostic (5.98e-3)" "unprognostic (4.79e-2)" "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (5.71e-3)" "unprognostic (8.92e-2)" "unprognostic (2.17e-1)" "unprognostic (4.35e-3)" "unprognostic (6.77e-2)" "unprognostic (8.12e-3)" "unprognostic (8.74e-2)" "prognostic unfavourable (5.04e-8)" "unprognostic (6.73e-2)" "unprognostic (1.46e-1)" "unprognostic (5.89e-2)" "unprognostic (4.92e-2)" 5.3 1.2 17.1 3.9 18.7 9.2 3.6 29.0 24.6 7.1 11.9 8.9 0.0 21.1 3.4 1.2 1.4 4.0 7.9 3.0 18.1 14.9 3.3 0.4 14.9 7.2 13.1 13.4 1.0 3.1 0.9 1.4 10.5 10.7 1.0 4.9 1.7 2.1 1.4 1.6 2.5 27.1 3.2 10.4 3.3 7.8 4.9 9.0 0.2 1.1 0.0 8.9 3.0 2.7 1.7 0.1 3.5 0.2 0.0 0.2 0.1 0.1 0.1 4.7 0.4 0.0 0.0 28.7 0.2 0.3 0.2 0.0 6.3 1.6 9.9 3.5 0.0 0.5 2.4 0.0 0.0 0.0 0.2 8.0 0.0 0.0 0.1 0.0 24.8 0.0 0.0 0.0 0.0 0.0 6.5 1.2 0.0 0.1 0.2 0.6 1.4 0.0 0.5 0.0 1.6 0.2 0.2 2.6 1.9 0.0 0.0 0.0 0.3 0.4 0.0 0.0 3.7 0.0 0.0 32.2 13.0 13.9 0.0 0.0 0.7 3.5 0.1 3.3 0.1 0.2 0.1 1.7 0.0 0.0 0.1 1.2 0.2 0.2 0.4 0.0 0.0 0.0 0.1 0.1 17.1 18.7 29.0 24.6 18.1 14.9 13.1 13.4 10.7 9.0 MGAT4A "GnT-4a, GnT-Iva" ENSG00000071073 "Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A" Q9UM21 2 98619106-98731126 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 49.2" "Cell line enhanced" "Detected in many" "BEWO: 47.2;HUVEC TERT2: 17.6;TIME: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007608 Enhanced Approved "Golgi apparatus" "Secreted in other tissues" "Golgi apparatus" "HPA007608: AB_10602008" "prognostic unfavourable (4.30e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-1)" "prognostic unfavourable (6.48e-8)" "unprognostic (1.35e-1)" "unprognostic (2.28e-2)" "unprognostic (3.82e-3)" "unprognostic (1.89e-1)" "unprognostic (3.76e-1)" "unprognostic (3.58e-1)" "unprognostic (2.80e-2)" "unprognostic (2.32e-2)" "unprognostic (4.17e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.04e-2)" "unprognostic (2.04e-1)" 8.1 5.1 11.3 11.9 15.6 49.2 8.2 28.5 14.3 6.1 14.6 8.3 6.8 17.6 5.2 4.1 4.1 6.2 8.0 5.1 11.3 10.4 17.1 6.0 13.7 16.7 9.9 8.3 2.9 26.7 33.3 14.1 11.9 10.4 6.6 15.8 5.6 14.5 4.4 3.3 3.4 38.5 7.2 16.1 7.0 8.4 3.9 14.3 20.3 6.4 3.1 11.6 8.3 5.0 2.0 9.3 7.6 2.9 7.7 19.7 7.4 3.1 0.6 1.2 2.6 0.0 0.0 47.2 0.0 0.0 0.3 0.0 7.5 3.8 0.0 7.1 0.0 0.1 2.6 0.3 0.0 3.7 2.8 0.2 0.0 13.0 0.0 6.2 2.3 0.0 1.7 0.0 0.2 17.6 0.5 3.4 0.0 6.1 13.7 10.9 0.4 0.5 3.4 0.0 3.7 9.2 6.3 3.8 1.2 0.9 11.8 1.7 2.8 8.5 28.5 0.0 1.5 0.0 0.9 1.2 2.6 0.8 0.0 9.5 0.2 3.3 2.9 6.6 12.3 0.5 15.9 2.0 14.9 13.7 2.0 1.1 19.7 16.1 7.6 7.7 1.1 9.3 8.4 7.4 11.3 15.6 28.5 14.3 11.3 10.4 9.9 8.3 10.4 14.3 MGAT4B GnT-Ivb ENSG00000161013 "Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B" Q9UQ53 5 179797597-179806952 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 125.6;liver: 100.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 9 "eosinophil: 8.5" "Lineage enriched" "Detected in single" 9 "granulocytes: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052134 Uncertain "Intracellular and membrane" "HPA052134: " "unprognostic (2.01e-2)" "unprognostic (8.68e-3)" "unprognostic (1.40e-1)" "unprognostic (3.83e-2)" "prognostic unfavourable (6.15e-5)" "unprognostic (3.61e-3)" "unprognostic (7.57e-3)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (5.13e-2)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "prognostic favourable (5.78e-4)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.42e-1)" 13.2 22.8 9.1 19.5 8.2 9.5 18.7 15.3 13.5 8.7 77.3 5.9 10.1 61.7 9.2 10.4 16.8 10.7 26.0 20.6 9.5 5.4 31.9 100.0 17.1 15.6 6.3 5.2 9.1 13.4 10.3 8.3 14.4 6.3 8.8 30.9 10.1 19.2 8.2 8.4 12.1 125.6 7.5 4.9 12.5 22.3 11.2 5.6 7.0 16.6 14.6 10.0 9.5 13.7 0.9 0.6 8.5 0.7 0.0 0.6 0.2 21.9 22.2 10.9 25.3 33.6 18.0 19.0 13.0 26.2 11.9 9.4 24.3 61.1 3.7 33.5 30.0 16.6 16.0 29.3 9.0 30.6 8.5 11.2 20.1 21.2 23.7 14.2 3.5 19.5 20.6 12.0 15.0 24.4 7.3 10.1 20.0 24.4 2.1 11.8 6.7 8.9 5.5 8.7 10.4 35.6 42.6 18.0 10.6 19.5 20.2 35.1 13.8 14.4 29.7 30.0 13.3 16.8 20.8 8.6 9.9 9.3 36.0 17.8 21.6 0.0 0.7 8.5 0.3 0.1 0.1 0.0 0.5 0.2 0.6 0.9 0.4 0.6 0.3 0.0 0.5 0.5 0.0 0.2 9.1 8.2 15.3 13.5 9.5 5.4 6.3 5.2 6.3 5.6 MGAT4C HGNT-IV-H ENSG00000182050 "MGAT4 family member C" Q9UBM8 12 85955666-86838904 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "brain: 12.8;epididymis: 10.9;pituitary gland: 25.9;testis: 7.8;thyroid gland: 18.0" "Group enriched" "Detected in some" 13 "NTERA-2: 10.9;SCLC-21H: 4.8" "Cancer enriched" "Detected in single" 19 "thyroid cancer: 2.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016418 Approved "HPA016418: AB_1853854" "unprognostic (5.23e-2)" "unprognostic (2.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.32e-4)" "unprognostic (1.07e-1)" "unprognostic (9.64e-2)" "unprognostic (5.94e-3)" "unprognostic (1.88e-1)" "unprognostic (8.05e-2)" "unprognostic (1.89e-1)" "unprognostic (6.32e-3)" "unprognostic (3.51e-2)" "unprognostic (6.85e-10)" "unprognostic (3.15e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" "unprognostic (4.74e-3)" 1.0 3.0 5.5 1.0 12.3 1.1 0.9 4.9 12.8 1.3 1.2 2.5 0.4 0.9 1.0 10.9 1.1 1.1 1.2 3.6 9.4 3.9 1.0 0.9 1.0 0.9 3.0 9.3 0.9 0.9 0.9 25.9 0.8 10.6 1.1 1.2 0.0 0.9 2.4 0.8 1.0 1.0 1.0 4.3 0.9 1.0 7.8 5.1 0.0 18.0 0.0 0.8 0.9 0.6 0.5 0.3 0.8 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.0 10.9 0.1 0.0 0.1 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.1 0.8 0.2 0.1 0.3 0.2 0.0 5.5 12.3 4.9 12.8 9.4 3.9 3.0 9.3 10.6 5.1 MGAT5 GNT-V ENSG00000152127 "Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase" Q09328 2 134119983-134454621 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010919 Approved 96000 "HPA010919: AB_10601864" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.21e-2)" "unprognostic (3.65e-1)" "unprognostic (3.76e-1)" "unprognostic (4.45e-3)" "unprognostic (3.41e-3)" "unprognostic (5.68e-2)" "unprognostic (8.63e-3)" "unprognostic (1.59e-1)" "unprognostic (2.64e-1)" "unprognostic (5.97e-2)" "unprognostic (1.81e-2)" "unprognostic (9.27e-2)" "unprognostic (2.17e-2)" "unprognostic (1.91e-1)" 8.4 9.8 13.0 21.7 15.7 12.0 8.0 21.3 17.6 9.0 13.2 17.2 4.6 14.2 8.5 6.3 8.2 17.5 15.1 33.9 13.9 17.5 14.3 4.9 9.3 20.1 23.6 11.6 11.3 11.1 18.8 7.9 22.0 28.0 7.9 13.8 8.3 11.9 9.1 3.2 6.6 19.2 10.1 28.7 23.1 15.0 6.6 13.2 16.5 10.3 5.1 28.9 11.0 9.2 7.5 1.8 2.3 0.8 2.4 3.1 1.1 10.0 4.0 10.3 7.3 9.2 17.6 7.2 13.4 20.5 5.4 4.6 1.6 5.0 16.1 10.3 10.6 3.5 8.0 6.3 10.4 15.7 4.7 9.0 5.2 21.0 6.0 8.7 32.2 4.8 6.6 11.4 7.1 40.4 4.6 11.0 9.8 6.4 4.7 4.1 4.7 10.0 5.8 12.1 10.1 4.2 12.3 17.0 21.0 4.3 3.7 25.6 2.9 6.1 18.2 17.2 9.1 12.4 7.0 3.1 1.4 6.1 14.4 12.6 27.2 1.2 0.7 1.8 1.6 0.7 2.7 5.6 3.1 2.1 0.6 7.5 1.3 1.6 2.3 2.4 0.8 1.8 1.9 1.1 13.0 15.7 21.3 17.2 13.9 17.5 23.6 11.6 28.0 13.2 MGAT5B "FLJ25132, GnT-IX, GnT-VB" ENSG00000167889 "Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B" Q3V5L5 17 76868456-76950393 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 28.1" "Cell line enhanced" "Detected in many" "A549: 21.6;SCLC-21H: 11.1;U-138 MG: 13.1;U-2 OS: 14.2" "Group enriched" "Detected in many" 5 "glioma: 2.6;melanoma: 7.1;testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011082 Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" "Nucleoplasm, Mitotic spindle" "Cytokinetic bridge" "HPA011082: " "unprognostic (6.37e-2)" "unprognostic (9.16e-3)" "unprognostic (8.51e-2)" "unprognostic (1.43e-3)" "unprognostic (5.68e-3)" "unprognostic (1.33e-1)" "unprognostic (2.28e-3)" "unprognostic (1.52e-3)" "unprognostic (5.30e-2)" "unprognostic (3.89e-2)" "unprognostic (1.68e-1)" "unprognostic (5.67e-2)" "unprognostic (1.46e-7)" "unprognostic (1.66e-1)" "unprognostic (8.09e-3)" "unprognostic (1.04e-1)" "unprognostic (3.01e-1)" 1.1 1.2 9.3 1.1 13.4 1.0 0.9 4.4 28.1 1.0 0.9 1.1 0.0 0.8 1.1 0.7 0.9 1.0 0.9 0.8 5.5 2.8 0.9 0.7 1.0 0.9 2.3 8.1 1.2 0.8 1.0 0.6 1.1 2.6 0.8 0.8 1.1 0.8 0.8 0.7 0.9 0.9 0.8 0.7 1.4 1.0 2.3 1.7 0.0 0.8 0.0 0.9 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 21.6 4.4 2.2 0.0 0.0 2.3 0.3 0.9 7.9 4.7 0.0 0.5 0.0 1.7 1.0 0.1 1.0 0.2 2.1 0.0 0.3 0.0 1.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 1.2 1.4 0.1 0.0 0.0 1.0 0.0 0.0 1.2 2.2 3.0 3.8 4.5 6.2 0.0 11.1 4.2 3.8 1.7 3.4 0.1 0.1 4.0 13.1 14.2 0.2 4.1 0.0 0.0 0.5 0.4 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 13.4 4.4 27.4 5.5 2.8 2.3 8.1 2.6 1.7 MGEA5 "MEA5, NCOAT, OGA" ENSG00000198408 "Meningioma expressed antigen 5 (hyaluronidase)" O60502 10 101784443-101818465 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036141, HPA076501" Approved Supported Cytosol Cytosol "HPA036141: AB_10672079, HPA076501: " "unprognostic (4.34e-1)" "unprognostic (1.57e-1)" "prognostic unfavourable (8.69e-5)" "unprognostic (4.63e-1)" "unprognostic (2.06e-1)" "unprognostic (2.57e-2)" "unprognostic (2.65e-1)" "unprognostic (1.79e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-3)" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.01e-1)" "unprognostic (3.21e-2)" "unprognostic (1.90e-1)" "unprognostic (9.23e-3)" 29.5 17.5 51.9 27.4 54.4 49.3 35.5 58.9 51.4 24.5 27.0 29.0 20.9 17.6 29.9 36.8 26.0 23.3 19.1 27.4 46.0 29.8 27.7 28.6 24.0 40.1 30.7 43.6 33.8 20.9 53.3 22.1 25.5 42.6 31.6 26.5 30.7 24.4 26.3 25.4 36.6 28.5 37.4 29.5 35.2 23.9 21.9 35.4 32.9 25.9 11.8 39.5 34.3 26.7 8.1 3.3 14.7 5.6 6.8 7.1 1.4 30.6 15.6 22.9 44.3 14.7 35.7 15.9 21.6 21.9 10.1 17.4 11.5 19.7 20.5 15.8 25.7 22.1 21.3 27.2 21.5 30.0 14.6 20.5 21.8 8.9 15.9 15.1 11.6 34.5 30.6 17.3 41.3 18.7 14.4 38.1 17.1 15.6 15.9 15.8 12.6 15.8 22.2 25.2 15.0 16.9 27.8 9.9 17.6 19.3 10.5 27.0 27.6 16.5 28.3 15.6 15.1 22.5 24.7 19.1 30.3 16.4 19.6 26.0 8.5 10.5 2.1 6.8 7.1 2.0 5.6 6.4 4.9 6.1 1.3 8.1 6.8 5.7 14.7 6.8 5.6 3.3 4.5 1.4 51.9 54.4 58.9 51.4 46.0 29.8 30.7 43.6 42.6 35.4 MGLL "HU-K5, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-127823250 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 45.6;BJ hTERT+: 52.6;LHCN-M2: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 11.6;intermediate monocyte: 28.5;non-classical monocyte: 18.3;plasmacytoid DC: 30.4" "Group enriched" "Detected in many" 13 "dendritic cells: 30.4;granulocytes: 11.6;monocytes: 28.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm 4300000 Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavourable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" 72.2 6.7 29.4 22.6 29.7 7.5 39.0 32.8 36.9 13.3 36.3 8.3 8.4 16.5 8.7 10.8 63.8 16.3 24.1 35.5 23.6 10.2 22.6 32.1 32.4 6.0 15.4 17.8 3.9 3.6 1.7 5.0 18.9 10.2 10.6 27.6 10.0 31.4 13.6 40.9 11.9 22.3 13.6 12.2 19.2 17.5 3.2 15.5 2.4 6.4 33.4 19.7 14.4 14.5 1.8 30.4 11.6 28.5 0.6 0.9 6.0 11.0 9.9 0.0 0.0 17.4 20.6 1.3 45.6 52.6 10.1 16.3 0.3 4.5 2.8 12.7 15.4 0.4 0.0 6.0 5.6 4.9 0.1 0.3 7.1 0.0 6.3 0.0 0.3 7.7 3.5 18.9 20.7 21.4 0.0 0.5 42.0 1.1 0.0 0.1 0.0 15.8 0.0 5.4 23.4 37.9 1.2 5.8 0.4 7.8 15.5 2.7 0.7 0.4 27.4 11.1 3.3 26.7 6.2 0.0 0.0 9.3 23.0 0.6 34.3 4.2 2.8 11.6 0.2 28.5 0.9 1.8 0.2 0.3 3.1 0.2 0.0 0.0 0.5 0.6 18.3 30.4 0.0 6.0 29.4 29.7 32.8 36.9 23.6 10.2 15.4 17.8 10.2 15.5 MGMT ENSG00000170430 "O-6-methylguanine-DNA methyltransferase" P16455 10 129467184-129768007 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002786, HPA032135, HPA032136, HPA069497, CAB069881" Supported Enhanced Nucleoplasm Nucleoplasm "CAB002786: , CAB069881: AB_10002128, HPA032135: , HPA032136: , HPA069497: " "unprognostic (1.10e-1)" "prognostic favourable (9.42e-4)" "unprognostic (1.48e-1)" "unprognostic (5.81e-2)" "unprognostic (7.84e-3)" "unprognostic (1.67e-1)" "prognostic favourable (1.54e-4)" "unprognostic (6.54e-3)" "unprognostic (4.71e-2)" "unprognostic (2.03e-1)" "unprognostic (1.26e-1)" "unprognostic (6.32e-1)" "unprognostic (4.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" 11.7 11.3 7.4 15.5 7.6 7.1 11.3 3.5 9.1 8.3 12.2 10.0 19.6 10.8 15.3 17.1 9.9 15.2 14.1 10.5 7.1 7.1 12.6 45.6 7.5 11.6 8.6 6.6 12.3 16.5 5.7 5.8 4.5 9.2 11.2 3.4 11.8 14.9 24.5 14.4 9.2 9.6 10.9 8.1 8.6 9.9 11.7 3.9 16.0 10.2 14.9 14.7 12.6 13.0 20.3 17.7 6.5 15.3 18.2 21.2 16.6 0.0 2.6 2.8 13.3 5.8 12.1 10.4 5.9 6.6 4.3 4.2 16.2 17.3 12.1 9.5 7.6 7.9 1.7 6.3 1.9 0.0 1.0 2.4 5.9 10.3 9.0 0.2 6.9 7.7 0.0 2.5 0.0 0.0 0.0 8.5 5.3 21.8 9.5 12.4 0.6 10.4 11.0 0.0 4.7 7.9 5.9 2.8 7.0 7.1 2.9 0.0 11.4 9.4 0.0 5.7 2.9 0.0 0.0 0.0 0.0 6.1 0.0 3.9 0.0 2.6 15.3 6.5 19.1 14.8 18.6 20.3 17.5 17.8 15.8 19.9 17.6 18.9 1.8 18.2 13.7 17.7 21.2 16.6 7.4 7.6 3.5 9.1 7.1 7.1 8.6 6.6 9.2 3.9 MGRN1 "KIAA0544, RNF156" ENSG00000102858 "Mahogunin ring finger 1" O60291 16 4616493-4690974 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 16.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 16.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007653, HPA008033" Approved Approved Vesicles Vesicles "HPA007653: AB_1846304, HPA008033: " "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (4.24e-1)" "unprognostic (1.26e-2)" "unprognostic (9.96e-2)" "unprognostic (1.70e-1)" "unprognostic (4.03e-2)" "unprognostic (9.47e-2)" "unprognostic (6.41e-2)" "unprognostic (2.32e-1)" "unprognostic (9.06e-2)" "unprognostic (1.79e-1)" "unprognostic (5.04e-2)" 18.7 23.1 22.9 24.0 24.3 29.7 19.9 43.1 37.6 16.3 16.6 28.7 16.8 28.9 23.7 13.8 14.7 20.9 20.2 20.7 24.3 18.6 15.9 30.4 21.6 22.2 27.9 21.5 21.3 34.9 19.7 21.5 18.8 18.6 19.0 11.6 20.7 23.8 22.9 29.9 13.5 28.6 20.0 17.2 26.2 25.2 11.5 24.5 12.9 19.7 10.4 11.0 18.7 14.2 1.7 4.1 16.6 3.9 1.4 3.3 2.9 5.2 25.1 13.0 13.3 7.8 7.6 17.8 11.3 8.0 9.6 8.1 16.6 12.6 15.6 14.7 13.7 8.5 10.4 9.3 2.8 21.6 11.5 8.5 17.6 22.8 14.3 12.3 21.2 14.1 6.1 13.3 5.7 9.1 12.4 11.4 6.5 23.1 12.8 16.5 19.2 11.0 23.5 6.8 20.9 8.4 15.4 20.9 17.4 18.8 20.3 11.3 12.3 12.2 16.1 17.8 9.9 50.1 9.7 18.2 14.1 10.5 7.6 12.4 12.8 4.5 3.5 3.4 2.7 3.9 2.5 1.4 1.5 2.3 2.3 1.7 3.3 2.0 16.6 1.4 2.4 4.1 1.7 2.9 22.9 24.3 43.1 37.6 24.3 18.6 27.9 21.5 18.6 24.5 MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 382.8" "Cell line enhanced" "Detected in many" "ASC diff: 335.0;ASC TERT1: 129.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 46.1;myeloid DC: 34.1" "Group enriched" "Detected in many" 15 "dendritic cells: 34.1;monocytes: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavourable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favourable (1.97e-4)" "unprognostic (4.19e-1)" 127.9 106.0 18.5 10.8 32.6 9.5 116.8 10.3 14.0 9.3 39.7 9.6 2.6 17.0 4.1 6.4 19.5 6.9 26.6 12.1 19.6 13.9 56.9 382.8 42.0 2.7 18.9 8.9 3.1 12.4 0.8 5.3 8.7 18.4 23.5 28.3 3.0 14.7 8.2 8.9 7.0 15.5 11.5 20.1 0.9 10.3 6.8 12.0 0.0 69.9 13.9 3.6 32.6 37.2 0.2 34.1 2.7 46.1 0.0 0.2 13.0 0.0 30.0 7.1 8.3 335.0 129.3 0.0 24.6 25.2 13.4 20.9 11.3 50.2 0.0 3.0 31.4 0.1 18.6 39.3 12.2 0.0 2.5 10.2 16.6 39.9 78.3 19.8 0.0 83.9 43.9 40.9 43.2 23.5 7.2 0.0 28.8 6.1 0.0 8.0 59.7 23.8 0.0 4.2 13.5 30.2 59.3 1.3 1.0 38.4 24.6 1.0 26.6 11.2 14.8 13.8 1.8 27.1 31.7 0.0 0.0 0.0 45.5 31.6 0.4 2.7 46.1 0.4 0.0 7.0 0.1 0.2 0.0 0.0 34.1 0.0 0.0 0.0 1.5 0.0 1.5 9.6 0.2 13.0 18.5 32.6 10.3 14.0 19.6 13.9 18.9 8.9 18.4 12.0 MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 53.8;U-937: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 46.9" "Group enriched" "Detected in many" 4 "dendritic cells: 46.9;monocytes: 25.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA010707 Approved "HPA010707: AB_1853922" "unprognostic (9.35e-2)" "unprognostic (6.13e-2)" "unprognostic (4.33e-2)" "prognostic favourable (5.26e-5)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (4.38e-2)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (6.41e-2)" "prognostic favourable (3.22e-9)" "unprognostic (4.10e-1)" "unprognostic (9.91e-2)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" 26.9 30.2 6.9 9.7 10.8 7.4 29.0 12.6 9.3 16.4 27.3 7.3 31.3 27.3 12.2 19.4 54.9 14.7 42.0 26.9 7.4 9.0 25.3 79.1 20.6 21.6 10.1 5.9 10.6 27.8 16.4 18.2 19.2 10.2 23.3 25.4 14.7 30.4 36.7 20.4 24.2 60.3 13.3 10.7 19.6 15.2 29.0 8.8 8.3 23.7 40.9 26.8 19.1 22.6 0.5 46.9 8.1 25.9 5.8 8.8 8.8 7.5 11.1 5.7 0.0 0.9 3.0 3.5 1.3 12.5 0.6 2.1 11.5 53.8 0.0 31.5 3.3 14.4 10.1 15.5 0.9 4.2 9.1 33.3 12.1 45.4 2.7 28.6 25.7 10.5 38.2 0.4 2.4 31.5 13.8 5.1 4.5 6.2 0.0 4.6 1.3 11.2 2.3 6.6 10.1 29.3 16.3 14.4 4.3 10.2 16.0 12.1 10.2 38.0 19.9 1.1 5.5 1.5 1.2 5.9 4.0 1.8 0.7 48.5 2.5 8.1 25.9 7.0 1.1 15.4 0.7 0.3 1.9 0.9 35.7 0.5 0.6 0.6 4.4 5.8 4.8 46.9 8.8 8.8 6.9 10.8 12.6 9.3 7.4 9.0 10.1 5.9 10.2 8.8 MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165630861-165661796 "Enzymes, Predicted membrane proteins" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 92.7;HDLM-2: 98.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053311 Approved Nucleoplasm 40000 Nucleoplasm "HPA053311: " "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-1)" "unprognostic (2.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.90e-1)" "unprognostic (3.96e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.60e-2)" "unprognostic (8.88e-2)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" 42.8 30.8 52.5 9.7 30.5 19.0 51.2 17.9 56.0 18.4 39.7 18.4 19.1 65.2 19.5 101.8 19.7 20.6 26.5 133.6 38.1 33.9 45.2 29.5 20.8 11.0 44.2 37.6 22.7 17.7 11.1 18.3 30.9 39.6 21.2 40.4 20.3 29.8 20.6 87.2 15.6 53.4 24.7 38.7 12.4 29.8 19.4 23.3 2.7 25.7 41.8 8.2 19.9 17.3 21.3 35.1 20.7 47.0 15.7 38.0 40.7 23.1 17.0 18.4 14.5 64.7 38.9 92.7 19.4 31.3 15.1 26.4 17.7 30.3 1.4 15.4 23.7 28.4 4.5 19.0 15.3 98.4 11.5 3.5 13.4 8.0 18.2 5.6 7.8 33.2 15.3 20.9 8.0 24.6 8.7 8.9 28.3 5.1 6.1 12.8 40.3 21.9 5.8 7.9 2.9 79.8 21.7 14.3 17.5 19.5 25.4 38.6 19.2 27.3 22.3 18.8 11.2 12.9 14.0 6.6 4.5 0.8 34.8 14.7 12.0 10.4 45.7 20.7 30.1 37.0 30.3 21.3 38.0 33.5 35.1 19.9 24.4 26.7 9.8 15.7 47.0 15.1 32.3 40.7 52.5 30.5 17.9 56.0 38.1 33.9 44.2 37.6 39.6 23.3 MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "Mindbomb E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870957 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019100, CAB037044" Approved Supported "Vesicles,Plasma membrane" "Plasma membrane" Vesicles "CAB037044: AB_1841007, HPA019100: AB_1853934" "unprognostic (1.38e-1)" "unprognostic (6.92e-2)" "unprognostic (7.29e-2)" "unprognostic (6.99e-2)" "unprognostic (5.66e-2)" "unprognostic (3.23e-2)" "unprognostic (8.45e-3)" "unprognostic (2.70e-1)" "unprognostic (5.42e-2)" "unprognostic (4.69e-2)" "unprognostic (3.78e-2)" "unprognostic (4.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.91e-3)" "unprognostic (1.73e-1)" "unprognostic (4.86e-2)" "unprognostic (1.85e-2)" 12.1 9.1 15.3 7.9 20.6 5.9 15.7 16.1 17.4 16.6 10.9 16.3 9.7 6.9 19.1 13.7 11.4 11.5 12.0 9.4 16.3 12.9 15.7 14.1 10.1 9.6 17.4 16.5 17.2 11.7 18.4 11.5 14.9 15.5 14.7 10.1 14.6 12.0 12.6 9.6 12.5 8.4 17.9 13.8 9.4 10.7 11.5 18.1 13.9 19.1 9.8 10.6 13.0 13.8 1.2 1.2 3.5 1.7 2.5 2.0 0.6 8.4 3.3 16.5 11.4 8.8 10.6 3.9 6.8 7.6 4.9 7.1 4.9 3.1 7.2 6.3 9.4 5.7 9.6 9.2 11.1 9.4 4.5 8.0 4.3 6.8 7.2 16.3 3.4 6.8 10.2 5.7 14.7 12.2 11.0 21.3 7.5 4.1 7.8 6.2 4.2 4.4 51.5 13.6 17.8 8.3 7.5 5.4 13.3 11.7 5.4 6.0 3.9 10.7 10.4 12.5 6.3 5.2 9.0 11.2 3.9 11.1 5.3 10.4 7.4 3.5 1.7 0.6 1.0 0.9 1.2 1.2 1.5 1.0 0.6 0.6 1.2 0.9 1.5 2.5 0.5 1.2 2.0 0.6 15.3 20.6 16.1 17.4 16.3 12.9 17.4 16.5 15.5 18.1 MIB2 "FLJ39787, skeletrophin, ZZANK1, ZZZ5" ENSG00000197530 "Mindbomb E3 ubiquitin protein ligase 2" Q96AX9 1 1615415-1630610 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" "Actin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "skeletal muscle: 72.5" "Cell line enhanced" "Detected in many" "HaCaT: 13.1;SCLC-21H: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068322 Enhanced "HPA068322: " "unprognostic (3.93e-2)" "unprognostic (6.02e-2)" "unprognostic (2.34e-2)" "unprognostic (6.60e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-2)" "unprognostic (7.36e-3)" "unprognostic (2.61e-1)" "unprognostic (1.54e-1)" "unprognostic (6.57e-2)" "unprognostic (1.15e-3)" "unprognostic (3.17e-2)" "unprognostic (2.22e-3)" "unprognostic (1.29e-1)" "unprognostic (3.58e-2)" "unprognostic (2.49e-1)" "unprognostic (1.01e-2)" 6.4 3.9 8.7 6.4 10.0 4.5 4.7 8.8 11.5 4.8 6.9 7.1 4.7 5.3 5.1 5.4 11.4 4.1 3.7 6.1 9.1 7.9 5.5 6.2 5.1 3.7 5.3 7.1 5.8 7.0 3.7 9.4 4.0 5.7 4.7 3.7 6.6 5.4 6.5 72.5 9.6 4.6 5.4 3.4 9.0 8.5 5.2 5.8 7.4 5.9 9.7 4.1 4.5 4.1 2.9 9.2 1.9 0.1 7.3 4.7 1.0 6.5 0.9 0.4 1.5 1.7 0.6 9.1 3.1 1.4 1.0 2.3 1.3 1.6 0.7 4.4 0.9 13.1 0.5 2.0 0.0 3.4 5.6 0.5 1.9 1.2 2.4 0.8 2.2 1.4 1.4 0.6 0.2 0.5 2.6 1.2 0.2 1.0 3.6 8.3 1.1 10.4 6.1 1.9 8.9 0.1 0.8 14.0 5.1 5.2 0.7 5.0 1.0 3.2 0.6 0.9 2.1 5.1 0.9 6.8 2.0 1.8 2.3 2.6 1.1 0.0 0.1 1.9 4.3 0.1 4.3 2.6 3.3 4.7 0.0 2.9 3.9 2.9 0.5 7.3 0.0 9.2 2.3 1.0 8.7 10.0 8.8 11.5 9.1 7.9 5.3 7.1 5.7 5.8 MICAL1 "DKFZp434B1517, FLJ11937, FLJ21739, MICAL, NICAL" ENSG00000135596 "Microtubule associated monooxygenase, calponin and LIM domain containing 1" Q8TDZ2 6 109444062-109465968 "Enzymes, Predicted intracellular proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 51.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA030175, HPA030176, HPA030178" Approved 32000 "HPA030175: , HPA030176: , HPA030178: AB_10600824" "unprognostic (1.07e-2)" "unprognostic (1.86e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-1)" "unprognostic (2.21e-1)" "unprognostic (2.71e-3)" "unprognostic (1.52e-2)" "unprognostic (1.92e-2)" "unprognostic (6.93e-2)" "unprognostic (1.94e-1)" "prognostic favourable (2.63e-7)" "unprognostic (2.31e-1)" "prognostic unfavourable (6.71e-7)" "unprognostic (2.05e-1)" "unprognostic (3.27e-1)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" 10.5 4.2 17.6 20.4 13.5 45.9 9.0 18.1 18.6 18.9 13.3 9.2 10.5 28.9 16.6 7.3 10.1 14.5 11.5 5.0 16.1 9.6 9.2 3.0 17.8 22.6 10.7 12.8 7.4 4.6 10.1 9.9 12.1 10.8 16.2 9.0 6.7 6.5 17.0 3.1 9.8 29.5 22.8 9.1 29.8 12.5 9.3 10.5 12.6 6.9 4.6 16.2 30.3 23.3 5.0 13.5 11.7 12.5 4.5 8.4 5.3 1.4 1.7 5.7 0.1 20.9 16.4 3.8 10.8 7.9 2.4 4.0 2.5 1.6 7.9 2.4 11.9 1.8 3.5 4.3 1.0 6.9 1.4 3.3 3.7 3.8 8.3 2.1 0.1 9.4 2.1 5.6 4.7 7.1 0.9 13.8 14.6 1.6 2.7 12.0 3.6 1.9 7.5 3.6 1.1 5.4 3.4 1.9 10.0 1.0 1.0 17.3 1.6 51.9 7.5 5.9 2.0 3.4 4.2 10.6 3.2 7.1 4.9 7.3 4.3 10.1 6.4 11.7 6.3 12.4 3.9 3.4 6.3 5.0 11.8 5.0 4.4 3.0 8.4 4.5 12.5 13.5 8.4 5.3 17.6 13.5 18.1 18.6 16.1 9.6 10.7 12.8 10.8 10.5 MICAL2 KIAA0750 ENSG00000133816 "Microtubule associated monooxygenase, calponin and LIM domain containing 2" "O94851, Q6ZW33" 11 12094008-12359144 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Actin-binding, Developmental protein, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 138.4" "Cell line enhanced" "Detected in many" "U-138 MG: 39.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "cerebellum: 138.4;cerebral cortex: 39.8" "Cell type enhanced" "Detected in many" "neutrophil: 12.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030437, HPA039895, HPA040438" Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" "Golgi apparatus, Cytosol" "Nucleoplasm, Plasma membrane" "HPA030437: AB_10601873, HPA039895: , HPA040438: AB_10672896" "unprognostic (2.68e-2)" "unprognostic (1.77e-2)" "unprognostic (5.77e-2)" "unprognostic (1.31e-1)" "prognostic unfavourable (6.88e-4)" "unprognostic (2.20e-2)" "unprognostic (3.60e-2)" "unprognostic (9.32e-2)" "unprognostic (2.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.15e-2)" "unprognostic (6.47e-2)" "prognostic unfavourable (3.63e-5)" "unprognostic (4.61e-2)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (1.67e-1)" 4.1 3.3 15.4 7.3 15.1 6.8 2.9 138.4 39.8 6.6 14.7 2.7 2.9 7.2 14.7 7.7 11.5 5.4 11.1 24.8 22.0 6.9 2.9 3.9 12.8 2.3 5.6 17.9 3.9 4.4 0.7 2.4 5.0 5.5 3.3 15.1 2.8 2.9 8.4 14.6 9.3 10.8 22.7 7.6 2.6 5.9 24.6 0.6 0.0 4.5 1.9 2.2 7.8 3.2 0.2 5.5 12.2 6.7 3.7 3.5 2.1 11.6 6.2 0.2 1.4 1.6 2.9 7.4 18.6 21.1 7.3 11.4 13.0 8.4 0.3 4.0 13.0 8.2 2.2 30.0 18.2 13.5 1.5 11.0 1.2 0.9 14.1 2.0 1.4 5.2 5.3 32.2 31.5 16.6 19.3 0.5 11.7 0.7 0.1 1.0 0.4 5.8 0.1 7.4 7.8 1.5 14.7 6.1 0.5 6.1 17.1 1.2 1.7 0.6 29.7 39.8 15.0 6.5 16.2 0.4 0.9 0.4 24.2 2.9 0.8 0.1 6.7 0.5 2.8 1.7 3.5 0.2 1.7 1.7 5.5 0.2 0.2 0.9 12.2 3.7 0.5 1.0 2.1 2.1 15.4 15.1 138.4 39.8 22.0 6.9 5.6 17.9 5.5 0.6 MICAL3 KIAA0819 ENSG00000243156 "Microtubule associated monooxygenase, calponin and LIM domain containing 3" Q7RTP6 22 17787649-18024559 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Exocytosis" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "WM-115: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 10.0;memory B-cell: 3.3;naive B-cell: 5.2" "Group enriched" "Detected in many" 6 "B-cells: 5.2;granulocytes: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000639, HPA003421, HPA034882" Approved Supported "Nucleoplasm,Plasma membrane,Midbody ring,Cytosol" "Nucleoplasm, Midbody ring" "Plasma membrane, Cytosol" "HPA000639: AB_10301319, HPA003421: AB_10601134, HPA034882: " "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-2)" "unprognostic (2.00e-2)" "unprognostic (7.68e-2)" "unprognostic (2.06e-1)" "unprognostic (4.71e-2)" "unprognostic (3.07e-3)" "unprognostic (3.41e-1)" "unprognostic (1.01e-1)" "unprognostic (4.58e-1)" "unprognostic (3.82e-1)" "unprognostic (8.86e-3)" "unprognostic (1.36e-2)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" 10.1 9.0 15.4 20.7 19.2 10.2 9.6 62.2 25.0 12.8 22.4 30.0 8.8 8.3 30.3 14.0 13.8 28.6 9.5 23.7 15.4 13.8 8.7 16.8 6.1 15.2 21.6 15.6 20.2 10.2 30.4 11.0 11.9 19.4 11.8 16.5 14.2 8.0 14.8 28.0 14.7 13.2 26.1 20.9 12.2 11.1 15.7 22.6 3.0 10.4 7.8 20.8 14.7 15.1 5.2 0.3 10.0 0.1 1.3 1.1 0.2 13.7 15.1 8.0 13.0 6.0 7.8 9.7 12.1 13.2 17.2 13.6 14.4 1.9 15.4 6.2 16.5 15.9 11.8 14.0 16.7 14.9 11.2 16.0 16.1 6.0 4.0 7.1 8.6 6.3 11.2 18.1 19.2 10.0 17.5 9.9 6.3 12.3 6.7 4.4 5.5 9.9 9.4 12.0 0.7 13.8 9.7 21.2 8.3 17.1 10.9 25.8 4.3 3.0 17.6 17.7 11.4 12.1 25.2 6.5 11.5 20.6 15.4 3.2 50.7 10.0 0.0 0.1 0.5 0.1 0.8 3.3 0.6 0.5 0.1 5.2 0.3 0.2 0.2 1.3 0.0 0.3 1.1 0.2 15.4 19.2 62.2 25.0 15.4 13.8 21.6 15.6 19.4 22.6 MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 56.8;AF22: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002878, HPA003715" Approved Approved "Centriolar satellite" "Centriolar satellite" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavourable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" 13.4 3.6 6.5 10.4 8.4 0.3 8.6 16.3 7.1 17.5 21.5 3.8 11.7 7.7 17.9 11.3 12.2 7.7 13.1 13.2 6.2 4.2 7.9 4.9 10.4 4.2 4.5 3.7 12.0 4.8 2.7 6.6 7.8 4.9 14.6 12.8 15.9 7.1 19.1 2.8 3.9 8.7 30.6 2.6 1.3 5.3 6.5 4.1 0.8 6.2 7.1 5.8 17.1 20.5 1.0 0.7 3.3 0.0 0.0 0.1 0.1 12.2 56.8 43.0 6.6 2.5 3.6 5.3 7.7 6.4 7.9 8.1 10.4 3.7 4.1 2.5 7.0 8.4 3.5 5.3 5.9 0.2 5.1 0.9 8.1 0.2 1.1 0.0 0.2 4.1 2.8 5.2 5.5 7.6 0.6 0.7 3.1 1.9 1.6 0.1 13.7 4.1 1.2 11.0 0.0 5.8 11.3 3.0 1.1 3.3 9.7 3.6 6.7 0.0 4.8 2.6 0.3 13.3 6.7 0.6 0.3 0.1 5.6 0.0 12.8 0.1 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.1 6.5 8.4 16.3 5.2 6.2 4.2 4.5 3.7 4.9 4.1 MIF "GIF, GLIF" ENSG00000240972 "Macrophage migration inhibitory factor" P14174 22 23894004-23895227 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Isomerase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 127.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003868, CAB005284" Approved Approved Nucleoplasm,Cytosol "Secreted to blood" 13800000 14000000 Cytosol Nucleoplasm "CAB005284: AB_648587, HPA003868: AB_1079290" "unprognostic (1.68e-1)" "unprognostic (7.79e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.36e-2)" "unprognostic (9.48e-2)" "unprognostic (1.22e-3)" "unprognostic (2.17e-2)" "unprognostic (1.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.28e-2)" "unprognostic (2.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" 30.6 49.8 43.9 42.0 39.9 46.0 71.6 19.0 66.1 23.0 42.7 10.4 55.6 39.9 22.5 113.3 51.9 23.3 42.5 60.7 42.8 40.3 71.8 58.8 46.2 113.9 33.5 43.7 24.5 80.2 16.2 41.1 30.5 45.2 54.8 11.6 15.0 57.3 101.2 36.0 63.3 50.6 26.7 78.3 42.5 56.2 24.9 19.2 19.0 28.9 43.7 16.7 21.4 44.6 56.8 42.5 17.6 23.8 38.3 52.7 66.0 48.9 10.9 2.4 11.0 0.9 2.2 18.4 18.5 3.1 5.9 7.7 8.1 8.1 23.3 14.7 1.3 21.8 2.5 11.2 0.7 19.6 127.1 8.8 9.9 16.9 4.8 34.0 20.7 4.7 6.7 3.5 1.7 4.7 13.6 11.8 2.0 24.6 23.1 63.0 14.0 59.3 29.7 4.1 65.3 4.6 3.4 31.9 37.2 11.8 12.5 30.5 16.1 10.2 13.5 5.2 35.0 3.1 0.4 51.4 18.1 24.0 21.1 12.7 10.6 16.3 23.8 17.6 37.4 22.3 52.7 56.8 51.8 40.4 31.6 49.1 46.1 38.0 7.1 38.3 14.6 42.5 48.3 66.0 43.9 39.9 19.0 66.1 42.8 40.3 33.5 43.7 45.2 19.2 MINDY1 "FAM63A, FLJ11280, MINDY-1" ENSG00000143409 "MINDY lysine 48 deubiquitinase 1" Q8N5J2 1 150996086-151008375 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 27.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 26.3;eosinophil: 19.1;neutrophil: 30.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028351, HPA028358, HPA061086" Approved Enhanced Nucleoplasm 240000 Nucleoplasm "HPA028351: AB_10611110, HPA028358: AB_10601102, HPA061086: " "unprognostic (5.73e-2)" "unprognostic (2.86e-1)" "unprognostic (5.47e-2)" "unprognostic (3.14e-1)" "unprognostic (3.39e-2)" "unprognostic (6.90e-2)" "unprognostic (1.47e-2)" "unprognostic (1.64e-1)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (9.22e-3)" "unprognostic (1.06e-1)" "prognostic favourable (3.43e-8)" "unprognostic (2.30e-1)" "unprognostic (7.95e-2)" "unprognostic (2.50e-2)" "unprognostic (6.06e-2)" 9.2 9.7 14.0 6.7 31.1 5.6 13.0 18.4 21.2 13.1 13.5 53.8 14.8 14.0 14.7 6.5 24.1 14.4 11.8 24.5 17.6 10.1 26.6 12.2 10.9 5.2 37.5 13.5 19.3 37.3 26.2 12.3 5.9 25.0 11.7 14.8 16.9 25.3 21.0 11.9 17.1 12.1 13.7 34.1 10.7 15.9 14.7 35.7 0.9 39.9 7.9 10.3 12.3 13.0 0.6 4.0 30.4 3.2 1.5 2.2 3.4 6.0 4.0 4.3 6.0 7.7 6.4 3.6 2.0 5.0 2.8 4.5 8.5 14.5 0.3 4.7 2.5 3.0 3.4 3.7 1.3 4.6 5.1 5.9 7.3 7.2 1.7 1.7 2.4 5.2 3.4 5.0 1.4 7.1 3.6 15.3 2.9 9.3 0.3 4.0 2.0 1.4 4.4 0.7 18.7 13.2 12.1 7.4 5.4 3.8 6.9 4.2 27.6 6.0 6.6 2.4 3.1 1.2 1.7 5.6 5.1 20.4 5.8 3.9 11.3 26.3 3.2 19.1 0.1 1.5 0.1 0.3 1.3 0.3 4.0 0.6 2.2 0.7 30.4 1.5 0.9 0.6 1.6 3.4 14.0 31.1 18.4 21.2 17.6 10.1 37.5 13.5 25.0 35.7 MINDY2 "FAM63B, KIAA1164" ENSG00000128923 "MINDY lysine 48 deubiquitinase 2" Q8NBR6 15 58771192-58861900 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051103, HPA063669" Approved Enhanced Nucleoplasm Nucleoplasm "HPA051103: , HPA063669: " "unprognostic (4.71e-2)" "unprognostic (8.92e-3)" "unprognostic (4.63e-2)" "unprognostic (4.13e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (8.60e-2)" "unprognostic (7.23e-2)" "unprognostic (7.09e-2)" "unprognostic (2.36e-3)" "unprognostic (4.74e-2)" "prognostic favourable (3.00e-8)" "unprognostic (2.53e-1)" "unprognostic (3.59e-1)" "unprognostic (6.76e-2)" "unprognostic (4.77e-2)" 14.0 9.2 15.5 8.8 14.7 5.6 11.1 41.0 15.4 12.4 8.8 12.4 11.8 5.8 13.0 8.0 11.8 11.7 10.4 16.7 14.6 12.6 16.9 5.8 12.5 6.1 16.2 15.5 11.7 6.4 15.5 12.5 21.9 14.9 15.0 6.6 11.7 7.7 11.8 6.1 11.4 6.5 13.6 16.9 9.4 7.8 6.2 15.8 8.6 15.8 5.4 6.0 13.1 9.1 4.6 2.9 5.5 3.1 1.9 5.5 1.4 5.7 2.8 4.0 2.4 6.1 11.2 6.4 5.3 11.3 1.6 2.4 4.5 2.9 2.9 5.8 6.3 5.6 7.3 4.3 2.6 3.0 2.6 4.1 3.1 4.0 3.7 3.1 3.8 4.9 7.2 1.9 4.5 4.0 7.1 3.3 3.9 0.7 3.8 2.3 8.6 1.5 1.7 11.6 3.1 4.9 6.5 3.7 2.7 3.8 5.4 9.6 1.6 6.6 4.7 2.3 2.1 39.9 2.3 3.0 4.2 2.9 5.2 5.1 5.6 5.5 1.8 3.3 3.2 1.6 5.5 2.7 2.8 3.5 0.6 4.6 2.4 3.3 3.9 1.9 3.1 2.9 2.2 1.4 15.5 14.7 41.0 15.4 14.6 12.6 16.2 15.5 14.9 15.8 MINDY3 "C10orf97, CARP, DERP5, FAM188A, FLJ13397, my042" ENSG00000148481 "MINDY lysine 48 deubiquitinase 3" Q9H8M7 10 15778170-15860520 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038400, HPA038406" Uncertain Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA038400: AB_10669724, HPA038406: " "unprognostic (9.20e-2)" "unprognostic (5.84e-2)" "unprognostic (3.09e-1)" "unprognostic (3.26e-1)" "unprognostic (1.99e-2)" "unprognostic (3.67e-1)" "unprognostic (8.29e-2)" "unprognostic (2.81e-2)" "unprognostic (3.85e-2)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (6.50e-2)" "unprognostic (1.32e-1)" "unprognostic (2.97e-1)" "unprognostic (1.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.19e-1)" 14.6 22.0 17.9 10.0 22.2 15.2 18.4 22.0 32.0 19.1 13.7 19.7 11.4 8.2 18.6 20.0 13.4 15.3 13.3 8.9 20.1 18.8 16.0 15.8 15.5 11.9 22.9 14.0 18.1 12.8 16.3 14.4 20.1 25.8 18.9 18.0 13.5 11.8 16.5 4.1 15.3 11.4 16.7 32.0 11.8 14.6 18.8 16.1 10.5 17.2 7.7 12.6 17.8 14.1 3.4 4.2 5.7 8.0 3.4 6.2 2.9 6.5 6.1 11.9 12.6 17.6 16.8 9.8 20.9 10.6 16.0 18.7 5.3 10.3 4.9 4.0 22.5 6.1 10.1 12.4 14.3 14.9 14.1 15.9 8.7 5.7 22.2 3.2 13.4 12.6 10.9 14.2 10.1 12.5 9.7 4.1 15.8 7.1 6.9 3.9 4.3 11.7 3.4 7.0 3.4 17.8 4.9 9.8 10.9 10.2 9.9 8.3 11.1 7.9 13.2 10.4 8.0 17.5 6.0 22.6 9.6 8.4 11.9 7.3 8.3 5.7 3.6 3.1 4.9 7.1 4.1 3.1 3.4 5.2 4.0 3.4 2.3 4.4 3.1 3.4 8.0 4.2 6.2 2.9 17.9 22.2 22.0 32.0 20.1 18.8 22.9 14.0 25.8 16.1 MINDY4 "C7orf67, FAM188B, FLJ22374" ENSG00000106125 "MINDY lysine 48 deubiquitinase 4" Q4G0A6 7 30771417-30892387 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 16.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "MAIT T-cell: 2.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.1;T-cells: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA019475, HPA030129, HPA030130" Approved Supported Vesicles,Cytosol "Vesicles, Cytosol" "HPA019475: AB_1848806, HPA030129: AB_10599621, HPA030130: AB_10601565" "unprognostic (2.96e-1)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.07e-1)" "unprognostic (6.01e-3)" "unprognostic (3.81e-2)" "unprognostic (5.25e-3)" "unprognostic (1.97e-1)" "unprognostic (5.59e-3)" "unprognostic (2.96e-2)" "unprognostic (1.92e-1)" "unprognostic (9.55e-2)" "unprognostic (1.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" 9.3 6.7 9.3 2.6 15.2 4.1 7.0 3.4 15.1 10.8 6.6 5.4 16.6 2.9 15.6 16.2 5.7 20.7 10.0 7.5 8.4 5.1 9.4 3.8 14.2 2.4 4.3 9.5 14.8 5.6 9.6 16.1 6.2 9.0 9.4 4.3 7.8 5.3 15.9 3.7 5.1 3.7 10.8 3.6 2.3 5.8 20.1 5.0 1.5 12.5 3.6 2.2 6.4 6.3 0.0 1.1 0.0 0.3 0.0 2.7 0.7 2.1 5.3 2.7 8.4 2.4 9.5 4.1 3.1 5.3 2.3 2.0 0.0 3.9 0.0 3.6 2.0 2.2 1.8 1.7 2.2 0.0 3.1 1.6 2.8 0.0 3.1 2.3 1.2 4.8 2.8 7.0 1.4 3.4 16.2 1.0 2.0 0.0 1.2 0.7 7.9 1.2 0.4 0.0 0.5 6.3 1.0 5.1 7.0 2.1 11.2 1.2 5.7 1.7 2.0 0.1 1.3 2.4 1.3 2.3 2.9 0.0 4.4 0.1 9.8 0.0 0.1 0.0 0.6 0.0 2.7 0.0 0.8 0.2 1.1 0.0 0.3 0.5 0.0 0.0 0.3 0.0 0.5 0.7 9.3 15.2 3.4 15.1 8.4 5.1 4.3 9.5 9.0 5.0 MINK1 "B55, MAP4K6, MINK, YSK2, ZC3" ENSG00000141503 "Misshapen like kinase 1" Q8N4C8 17 4833388-4898061 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056296 Approved "HPA056296: " "unprognostic (2.80e-1)" "unprognostic (3.83e-2)" "unprognostic (1.85e-1)" "unprognostic (6.62e-2)" "unprognostic (2.88e-1)" "unprognostic (3.26e-3)" "prognostic unfavourable (3.00e-4)" "unprognostic (4.64e-3)" "unprognostic (3.21e-1)" "unprognostic (2.78e-2)" "prognostic favourable (2.77e-4)" "prognostic unfavourable (9.27e-4)" "unprognostic (8.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.37e-1)" "unprognostic (2.47e-2)" "unprognostic (1.62e-1)" 12.7 14.8 31.4 18.2 46.8 14.9 14.2 30.8 43.5 15.2 26.0 32.6 8.8 33.1 12.4 7.7 40.0 14.3 15.6 9.0 28.4 12.8 13.8 10.0 23.3 17.1 28.6 27.3 27.5 21.5 16.5 15.4 17.4 29.0 14.3 20.7 14.5 21.1 11.3 8.3 47.3 31.1 11.4 24.8 20.0 22.3 14.5 30.9 9.0 12.7 14.6 16.8 14.9 24.1 2.6 1.2 6.4 1.6 0.3 3.0 2.3 18.4 33.9 7.9 12.8 12.6 9.2 22.8 14.8 13.5 11.8 10.0 12.8 12.9 13.2 17.1 15.5 37.6 5.9 26.6 5.8 18.9 16.5 9.4 21.5 10.0 8.3 3.5 18.5 9.8 20.0 11.1 10.3 12.7 10.1 11.5 8.7 11.0 5.6 8.0 6.2 11.0 7.0 6.5 8.0 18.1 19.0 8.3 6.6 15.3 12.8 9.6 11.5 4.9 18.4 12.6 5.7 21.3 14.0 6.6 5.3 2.7 11.3 7.6 8.5 0.0 1.6 6.4 2.7 1.6 3.0 2.6 2.8 2.1 1.2 1.5 2.0 0.8 1.3 0.3 0.8 0.8 2.8 2.3 31.4 46.8 30.8 43.5 28.4 12.8 28.6 27.3 29.0 30.9 MINPP1 MIPP ENSG00000107789 "Multiple inositol-polyphosphate phosphatase 1" Q9UNW1 10 87504875-87553460 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026859 Approved "Intracellular and membrane" 320000000 "HPA026859: AB_1853961" "unprognostic (9.15e-2)" "unprognostic (8.76e-3)" "unprognostic (2.08e-2)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (5.20e-3)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (4.55e-1)" "unprognostic (2.07e-2)" "unprognostic (6.54e-2)" "unprognostic (6.50e-3)" "prognostic unfavourable (6.98e-5)" "unprognostic (2.43e-1)" "unprognostic (2.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.01e-2)" 9.9 27.6 8.5 8.0 8.9 24.6 14.2 12.0 9.2 9.1 13.3 8.0 12.8 16.7 12.1 10.0 5.4 8.4 9.5 7.2 8.5 10.0 19.4 28.9 9.5 10.1 8.2 6.3 11.1 18.2 10.2 18.5 31.4 7.6 11.6 12.4 9.3 8.9 12.2 5.9 9.5 19.4 7.4 8.2 8.2 8.9 8.8 8.5 13.5 13.1 5.3 6.5 8.7 13.9 8.9 13.5 8.5 12.9 10.4 16.4 9.3 8.3 12.9 12.9 18.9 22.0 18.2 10.9 13.6 23.3 13.5 18.1 6.8 16.4 7.2 12.7 16.0 13.0 13.6 12.4 15.4 16.5 16.2 18.5 5.2 25.2 16.5 7.9 16.9 15.9 16.0 15.0 9.1 16.9 10.8 35.3 15.6 6.2 5.2 11.2 9.3 9.3 0.0 7.4 4.9 17.7 4.7 4.7 14.8 12.9 2.7 22.6 7.8 6.6 14.8 8.7 10.5 10.3 13.0 11.5 11.8 1.9 13.9 12.2 6.3 8.5 10.3 4.6 11.6 12.9 10.3 8.9 11.0 13.2 13.5 7.3 10.6 11.9 0.7 10.4 10.8 7.8 16.4 9.3 8.5 8.9 12.0 9.2 8.5 10.0 8.2 6.3 7.6 8.5 MIOX ALDRL6 ENSG00000100253 "Myo-inositol oxygenase" Q9UGB7 22 50486784-50490648 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 43 "kidney: 136.7" "Cell line enhanced" "Detected in some" "HDLM-2: 21.3;Hep G2: 4.8;Karpas-707: 11.4;U-266/70: 6.8" "Cancer enriched" "Detected in many" 16 "renal cancer: 56.0" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039451, HPA039562" Enhanced "HPA039451: AB_2676513, HPA039562: AB_2676574" "unprognostic (2.11e-1)" "unprognostic (4.32e-2)" "unprognostic (2.22e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (5.25e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-3)" "unprognostic (2.84e-1)" "unprognostic (4.72e-2)" "unprognostic (1.85e-2)" "unprognostic (9.83e-2)" "prognostic favourable (2.60e-6)" "unprognostic (1.77e-1)" "unprognostic (1.50e-1)" "unprognostic (1.36e-2)" "unprognostic (2.23e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.8 0.1 0.1 0.0 136.7 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.4 2.7 0.1 0.1 0.1 0.1 1.3 0.6 3.1 0.7 0.4 1.4 0.4 0.0 0.0 0.1 0.3 0.2 0.1 1.8 0.2 0.0 0.0 0.1 0.1 0.2 0.1 0.6 0.3 0.1 0.1 0.0 0.0 21.3 0.0 0.1 0.3 4.8 2.8 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.1 11.4 0.0 1.1 0.0 0.1 0.2 0.4 0.1 0.1 0.1 2.2 0.1 0.1 0.3 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.5 0.1 0.0 6.8 0.6 0.3 0.1 0.0 0.2 3.1 0.4 0.6 0.5 0.3 0.2 1.3 0.5 1.4 0.1 0.9 0.5 0.6 1.8 0.4 0.7 0.6 0.4 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889419 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favourable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" 7.3 14.9 6.2 7.1 12.2 4.4 11.0 4.7 10.3 8.1 12.2 12.9 12.1 8.4 9.6 20.4 14.4 17.1 11.7 16.9 8.8 5.3 24.7 12.0 8.2 8.4 5.1 8.0 8.5 14.7 8.1 15.4 5.3 9.1 10.9 13.1 9.1 12.9 10.1 16.2 22.0 8.9 11.5 4.4 6.5 9.8 13.9 4.9 8.9 10.9 15.7 11.1 11.2 8.6 9.2 6.5 1.2 10.6 9.7 10.0 3.9 8.9 10.1 5.0 11.7 11.5 15.5 10.7 6.5 10.1 9.8 8.2 13.4 17.8 10.5 6.6 5.2 22.6 11.5 13.6 12.2 6.1 7.3 4.6 4.8 11.5 9.4 10.7 2.5 7.6 17.1 10.1 9.0 12.2 8.8 1.7 15.2 6.6 7.6 6.0 6.9 10.2 8.5 13.5 9.1 21.8 6.0 11.8 3.9 6.9 11.4 13.6 11.7 6.0 6.7 6.0 5.0 9.8 6.9 1.7 2.4 5.6 10.3 5.5 7.4 0.0 3.0 1.2 7.9 3.7 10.0 9.2 7.7 7.1 6.5 7.7 7.4 7.3 0.0 9.7 10.6 5.6 5.1 3.9 6.2 12.2 4.7 10.3 8.8 5.3 5.1 8.0 9.1 4.9 MKNK1 MNK1 ENSG00000079277 "MAP kinase interacting serine/threonine kinase 1" Q9BUB5 1 46557408-46616843 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 72.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB027355, CAB037310, HPA071293" Approved Supported Nucleoplasm Nucleoplasm "CAB027355: AB_2266303, CAB037310: AB_1854049, HPA071293: " "unprognostic (4.05e-3)" "prognostic favourable (7.05e-4)" "unprognostic (5.28e-2)" "unprognostic (3.47e-2)" "unprognostic (1.64e-1)" "unprognostic (7.38e-2)" "prognostic unfavourable (1.24e-5)" "unprognostic (3.50e-2)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (2.14e-2)" "prognostic unfavourable (1.51e-5)" "unprognostic (7.02e-2)" "unprognostic (3.19e-2)" "unprognostic (4.67e-1)" "unprognostic (5.67e-3)" 17.6 12.0 10.7 16.2 10.5 16.8 12.1 13.7 12.3 9.2 12.6 11.0 9.6 9.7 11.9 13.3 12.2 11.1 11.4 12.3 10.8 7.0 9.4 10.8 16.1 16.3 9.9 9.8 10.7 72.3 8.6 11.3 15.4 11.0 9.9 13.3 11.9 10.6 7.7 12.8 10.2 12.7 13.3 8.1 25.6 11.7 7.6 8.7 12.5 8.8 15.8 10.9 10.9 14.5 4.9 6.0 33.3 12.1 5.0 22.0 6.1 19.3 13.1 8.7 9.6 7.8 11.6 11.6 9.8 9.8 11.9 16.2 15.1 8.0 12.8 12.1 9.8 23.5 14.5 16.0 12.7 21.9 12.9 27.0 15.0 12.9 12.2 14.4 22.0 15.2 11.1 15.5 8.5 13.9 14.1 9.4 6.4 12.7 10.3 12.9 5.9 15.6 9.5 18.2 12.8 12.7 20.3 6.1 5.5 18.9 17.1 15.8 11.5 16.1 11.2 4.3 0.9 13.5 10.9 8.0 13.3 10.9 8.4 18.6 7.9 3.9 12.1 14.3 7.5 11.5 22.0 4.6 6.6 6.8 6.0 4.9 4.8 7.0 33.3 5.0 8.1 4.4 4.4 6.1 10.7 10.5 13.7 12.3 10.8 7.0 9.9 9.8 11.0 8.7 MKNK2 "GPRK7, MNK2" ENSG00000099875 "MAP kinase interacting serine/threonine kinase 2" Q9HBH9 19 2037465-2051244 "Enzymes, Predicted intracellular proteins" "Apoptosis, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.5" "Cell line enhanced" "Detected in all" "HHSteC: 78.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021875, CAB037253, HPA070499" Supported Supported "Nuclear bodies" "Nuclear bodies" "CAB037253: AB_1079401, HPA021875: AB_1854050, HPA070499: " "unprognostic (8.76e-2)" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "prognostic favourable (4.86e-5)" "unprognostic (3.08e-1)" "unprognostic (1.59e-2)" "unprognostic (6.42e-3)" "unprognostic (1.35e-1)" "unprognostic (4.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.08e-1)" "unprognostic (6.56e-2)" "unprognostic (4.07e-2)" "prognostic favourable (4.01e-4)" "unprognostic (1.63e-1)" "unprognostic (1.60e-1)" "unprognostic (1.59e-1)" 30.3 15.6 7.6 24.2 8.5 31.9 31.1 16.6 9.7 12.5 22.7 6.5 21.4 13.1 9.3 18.4 42.1 11.0 21.7 33.3 7.5 5.7 10.3 22.0 24.5 16.9 10.3 3.3 13.8 53.1 8.3 13.4 16.7 9.2 18.8 8.4 14.2 35.2 32.5 207.5 19.3 15.1 13.0 7.0 27.8 16.7 9.1 9.1 16.0 32.3 47.1 32.8 21.2 63.6 10.7 5.9 26.9 8.0 6.1 7.5 2.2 13.1 14.8 6.3 13.8 46.9 17.0 14.2 7.8 5.6 5.6 5.7 9.5 23.1 18.6 10.8 15.7 16.3 7.9 22.8 2.5 25.3 7.4 7.5 12.5 10.1 78.8 14.7 13.6 18.1 55.5 10.6 22.6 13.2 12.9 33.3 3.8 7.7 8.8 12.3 16.5 16.2 16.9 1.8 23.5 9.9 8.6 8.7 10.4 18.3 27.1 33.4 11.2 18.3 19.8 2.0 8.0 8.2 9.3 54.3 21.0 18.2 16.5 11.1 3.7 2.7 6.1 5.7 5.6 6.3 5.1 10.7 5.8 6.2 4.8 10.2 3.7 4.5 26.9 6.1 8.0 5.9 7.5 2.2 7.6 8.5 16.6 9.7 7.5 5.7 10.3 3.3 9.2 9.1 MKRN1 RNF61 ENSG00000133606 "Makorin ring finger protein 1" Q9UHC7 7 140453040-140479569 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000567 Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Nucleoplasm, Cytosol" "Nuclear membrane" "HPA000567: AB_1079299" "unprognostic (9.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-3)" "unprognostic (1.65e-2)" "unprognostic (2.41e-1)" "unprognostic (4.87e-3)" "unprognostic (1.24e-2)" "unprognostic (8.02e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (1.35e-1)" "unprognostic (2.89e-3)" "unprognostic (5.76e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (1.22e-2)" 16.8 17.6 26.8 20.8 28.8 69.9 20.1 37.2 32.6 20.4 39.6 16.1 19.7 28.4 20.1 18.6 23.3 22.2 22.4 38.5 24.9 29.8 20.6 17.5 23.6 18.3 25.7 23.3 24.9 27.3 28.2 21.5 31.7 29.4 21.0 33.7 19.4 24.8 23.1 38.5 24.4 26.6 26.3 20.5 22.5 21.7 95.4 20.2 21.0 23.6 18.8 22.3 25.3 36.4 13.1 7.5 39.3 10.5 12.8 17.8 6.4 27.9 21.6 16.9 25.0 26.8 23.5 23.9 19.3 25.1 15.2 17.6 8.8 29.5 20.3 30.3 18.8 13.6 19.0 21.2 19.3 40.2 16.5 21.1 13.0 16.3 21.6 18.0 32.7 23.4 32.0 17.1 16.2 15.1 16.6 25.7 14.6 24.1 21.1 32.4 43.4 16.0 15.3 14.5 31.1 24.4 32.4 23.4 24.2 24.2 32.8 34.5 16.1 15.7 21.4 10.7 8.5 26.1 17.6 61.3 44.9 17.8 30.6 28.4 22.0 19.4 9.2 39.3 6.7 8.7 8.0 13.1 13.0 10.1 7.5 10.9 17.8 11.3 18.1 12.8 10.5 2.5 14.0 6.4 26.8 28.8 37.2 32.6 24.9 29.8 25.7 23.3 29.4 20.2 MKRN2 "HSPC070, RNF62" ENSG00000075975 "Makorin ring finger protein 2" Q9H000 3 12557014-12583713 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037559, HPA037560" Enhanced Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA037559: AB_10672460, HPA037560: AB_10696936" "unprognostic (4.17e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-2)" "unprognostic (5.99e-2)" "unprognostic (3.89e-2)" "unprognostic (1.47e-2)" "prognostic unfavourable (1.58e-4)" "unprognostic (4.38e-1)" "unprognostic (8.49e-2)" "unprognostic (2.86e-1)" "unprognostic (1.42e-1)" "unprognostic (2.56e-3)" "prognostic favourable (6.04e-4)" "unprognostic (3.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.33e-2)" "unprognostic (3.32e-2)" 13.7 10.4 15.1 11.1 18.3 16.4 11.6 29.3 19.5 13.7 12.7 12.4 16.1 12.5 15.2 12.3 16.2 13.1 10.9 26.3 14.0 15.1 13.7 12.5 12.1 12.6 15.2 14.8 20.8 26.6 17.3 11.9 14.4 16.0 11.3 11.5 13.2 12.8 13.1 24.5 12.8 10.9 15.9 16.2 10.1 11.7 46.1 14.7 15.4 18.2 17.0 13.7 13.0 12.6 21.3 19.0 30.0 20.3 25.3 26.2 18.7 10.7 12.4 14.8 11.1 23.2 22.6 28.7 16.6 17.8 21.2 17.8 12.0 10.7 15.2 9.5 18.3 6.6 19.3 16.3 18.9 17.2 16.2 21.7 14.2 16.0 26.7 21.3 9.9 25.1 15.2 24.6 15.6 17.4 20.2 21.6 18.2 15.1 26.1 11.1 9.9 21.8 25.2 14.3 17.1 14.9 14.2 8.7 14.7 14.4 7.4 14.8 16.7 18.9 17.5 14.5 14.3 17.2 22.5 16.4 33.6 32.7 15.7 25.5 21.8 18.9 17.2 30.0 21.5 15.6 26.2 21.3 22.1 22.0 19.0 16.4 23.9 22.3 15.0 25.3 20.3 15.1 23.4 18.7 15.1 18.3 29.3 19.2 14.0 15.1 15.2 14.8 16.0 14.7 MKRN3 "D15S9, MGC88288, RNF63, ZFP127, ZNF127" ENSG00000179455 "Makorin ring finger protein 3" Q13064 15 23565678-23630075 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.4" "Cell line enhanced" "Detected in many" "K-562: 17.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD8 T-cell: 5.7" "Lineage enriched" "Detected in many" 4 "T-cells: 5.7" "Low region specificity" "Detected in many" HPA029494 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA029494: AB_10603873" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (4.26e-1)" "unprognostic (1.86e-3)" "unprognostic (1.04e-3)" "unprognostic (1.15e-2)" "unprognostic (6.27e-4)" "unprognostic (1.51e-1)" "unprognostic (8.52e-2)" "unprognostic (7.05e-2)" "unprognostic (4.97e-3)" "unprognostic (2.86e-1)" "unprognostic (1.05e-4)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (8.91e-2)" "unprognostic (9.78e-2)" 1.0 0.7 5.1 1.2 10.4 4.0 1.2 1.0 11.1 0.5 1.1 8.4 0.0 1.3 1.3 3.2 5.6 0.9 0.8 0.8 6.4 3.4 1.1 0.7 1.0 1.9 14.4 3.0 1.2 1.7 0.5 3.8 8.5 5.1 1.2 0.8 3.1 5.2 1.0 1.4 1.2 1.9 0.8 8.2 1.5 0.9 5.7 13.3 5.0 0.9 1.1 1.7 0.7 0.6 1.0 0.9 1.3 0.5 0.4 5.7 0.7 4.7 3.4 3.0 3.1 0.0 0.0 7.1 0.3 0.0 2.9 2.0 8.5 0.0 0.2 0.1 0.0 8.2 1.3 0.0 0.7 0.0 0.3 6.8 9.1 0.3 0.2 8.0 6.1 0.1 0.0 6.0 0.0 0.0 17.5 7.5 0.8 0.0 8.4 3.5 0.0 10.4 6.0 1.1 4.2 0.0 0.1 0.7 2.4 0.0 3.4 0.0 2.7 2.4 0.1 8.0 6.7 0.4 5.6 9.4 11.5 5.6 4.7 0.1 0.1 1.3 0.5 0.4 1.8 0.2 1.0 1.0 0.6 1.4 0.2 0.9 2.0 5.7 1.3 0.4 0.3 0.9 0.4 0.7 5.1 10.4 1.0 6.8 6.4 3.4 14.4 3.0 5.1 13.3 MLYCD "hMCD, MCD" ENSG00000103150 "Malonyl-CoA decarboxylase" O95822 16 83899126-83927026 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 39.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" HPA031625 Enhanced "HPA031625: AB_10602028" "unprognostic (6.23e-2)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.26e-1)" "unprognostic (2.36e-2)" "unprognostic (1.28e-1)" "unprognostic (6.23e-2)" "unprognostic (1.84e-4)" "unprognostic (2.33e-1)" "prognostic favourable (2.61e-7)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (9.56e-2)" "unprognostic (1.51e-3)" 6.6 10.1 3.3 3.7 4.2 2.3 4.6 2.4 5.4 4.1 6.9 6.3 6.2 4.6 4.4 4.4 5.1 4.9 7.0 39.1 3.7 3.3 6.7 17.4 4.1 3.6 6.9 3.1 6.2 21.5 6.9 5.1 3.1 4.6 5.6 4.4 8.0 6.4 4.1 31.0 4.0 5.1 5.8 3.3 3.8 6.7 7.1 5.7 3.3 5.6 5.7 4.6 6.4 5.4 0.7 0.7 2.3 0.8 0.1 0.9 0.2 0.5 2.3 1.6 2.6 4.9 2.4 3.6 1.1 1.7 1.1 0.5 2.2 1.6 0.4 2.8 2.1 2.4 2.7 0.8 1.0 1.8 2.1 1.6 0.9 1.3 2.8 1.4 3.2 3.0 2.7 0.7 1.1 1.2 2.1 0.8 1.3 4.3 1.5 4.4 2.0 1.0 3.4 1.4 2.1 2.9 2.7 2.4 2.2 4.4 0.6 2.0 4.2 1.8 1.6 1.7 0.4 1.3 0.5 2.7 2.6 3.1 1.7 2.1 1.9 0.8 0.7 2.3 0.5 0.5 0.3 0.7 0.8 0.7 0.7 0.3 0.8 0.9 0.3 0.1 0.8 0.3 0.0 0.2 3.3 4.2 2.4 5.4 3.7 3.3 6.9 3.1 4.6 5.7 MMAB "cblB, CFAP23" ENSG00000139428 "Methylmalonic aciduria (cobalamin deficiency) cblB type" Q96EY8 12 109553737-109573874 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039017 Approved Approved Mitochondria Mitochondria "HPA039017: AB_10673603" "unprognostic (1.16e-1)" "unprognostic (1.25e-2)" "unprognostic (1.90e-1)" "unprognostic (1.79e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (4.22e-1)" "unprognostic (2.04e-2)" "unprognostic (5.15e-2)" "unprognostic (1.47e-3)" "unprognostic (2.58e-1)" "prognostic favourable (1.55e-4)" "unprognostic (4.90e-2)" "unprognostic (1.51e-1)" "unprognostic (2.23e-1)" "unprognostic (9.65e-2)" 7.3 26.1 12.7 7.2 12.2 5.2 13.0 7.2 17.2 7.0 12.2 12.6 9.4 12.7 7.7 21.9 14.8 9.8 11.8 18.1 11.6 11.5 13.6 47.9 11.8 13.0 12.4 8.2 14.2 20.2 9.1 11.7 5.3 14.0 15.7 8.3 11.2 15.1 10.6 16.5 8.9 8.5 8.7 15.7 6.7 10.7 7.8 14.8 4.3 16.6 15.7 7.5 6.0 7.5 14.1 9.4 3.8 8.1 8.5 13.9 9.2 13.2 9.0 9.4 7.4 3.8 7.8 4.8 2.9 6.9 4.3 4.6 10.5 12.5 8.5 8.6 3.3 13.9 6.2 23.0 2.0 3.3 25.3 3.5 6.7 17.2 13.7 7.4 3.1 10.5 14.4 9.5 4.2 4.1 11.1 6.5 3.1 30.7 6.7 12.0 11.6 12.9 5.6 3.6 22.1 19.2 12.6 14.6 6.3 6.7 12.4 5.1 25.9 20.9 2.2 3.8 1.5 2.6 4.3 5.1 3.8 9.6 8.2 9.1 10.2 3.8 5.9 0.8 13.5 8.1 10.8 11.1 9.9 10.7 9.4 14.1 13.9 13.1 1.7 8.5 8.0 7.7 4.7 9.2 12.7 12.2 7.2 17.2 11.6 11.5 12.4 8.2 14.0 14.8 MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183729 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 61.1;intestine: 136.0;kidney: 64.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 95.0;BJ hTERT+: 142.9;HSkMC: 92.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 129 "neutrophil: 61.1" "Lineage enriched" "Detected in single" 129 "granulocytes: 61.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 26.8" "CAB000013, HPA052583, HPA056072" Enhanced 99000 "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" 26.5 0.4 0.4 3.4 7.4 1.9 14.7 0.4 0.7 4.8 65.6 0.1 18.4 74.0 2.8 8.1 0.7 0.9 8.5 1.8 0.3 0.4 64.9 11.5 13.7 3.0 2.1 0.2 0.9 0.6 0.0 0.6 35.0 8.6 18.3 0.4 1.3 3.7 11.3 11.7 1.4 136.0 0.6 0.9 2.7 0.7 1.0 1.2 13.2 1.0 5.3 2.3 3.4 4.9 0.1 0.4 61.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 38.6 95.0 0.2 21.2 142.9 10.8 28.1 0.0 0.0 23.4 0.0 18.8 0.0 0.7 0.8 26.1 0.0 0.1 0.0 0.0 0.0 30.9 0.0 0.0 92.1 0.1 5.8 41.6 8.2 0.0 0.0 17.3 0.1 0.0 0.1 0.9 0.1 38.8 18.2 0.1 0.6 0.2 0.0 0.2 0.0 0.0 4.1 0.0 0.0 23.3 46.7 0.1 15.9 3.7 0.0 0.0 30.8 5.6 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 61.1 0.0 0.0 0.4 0.0 0.0 0.4 7.4 0.4 0.7 0.3 0.4 2.1 0.2 8.6 1.2 MMEL1 "MMEL2, NEPII, NL1, NL2, SEP" ENSG00000142606 "Membrane metalloendopeptidase like 1" Q495T6 1 2590639-2632990 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 30.2" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 17.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 8.5" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007876, HPA008205, CAB020786" Uncertain "Intracellular and membrane" "CAB020786: , HPA007876: AB_1854012, HPA008205: AB_1854011" "unprognostic (5.80e-2)" "unprognostic (4.61e-2)" "unprognostic (1.87e-1)" "unprognostic (4.27e-2)" "unprognostic (1.33e-1)" "unprognostic (2.71e-2)" "unprognostic (1.45e-1)" "unprognostic (7.96e-2)" "unprognostic (1.36e-2)" "unprognostic (2.37e-1)" "unprognostic (4.54e-3)" "unprognostic (2.44e-2)" "unprognostic (4.79e-2)" "unprognostic (3.18e-1)" "unprognostic (2.82e-1)" "unprognostic (2.18e-3)" "unprognostic (7.01e-4)" 1.5 0.5 0.8 1.8 8.5 0.6 1.8 0.4 0.6 4.3 4.2 0.4 1.9 3.2 0.8 10.3 3.0 3.0 9.6 1.3 1.0 2.6 1.4 0.4 1.4 1.4 1.7 0.4 1.1 7.3 0.3 0.4 0.7 0.5 4.2 1.4 0.4 2.0 2.0 0.4 0.3 2.6 0.9 0.7 1.4 7.9 30.2 0.9 0.8 1.1 0.8 0.8 3.7 1.6 0.6 1.1 6.6 5.1 2.3 6.1 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.9 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.5 0.0 17.4 0.0 1.6 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 1.5 6.6 0.5 3.9 0.3 0.6 1.7 0.7 1.1 0.0 4.5 2.2 1.0 2.3 5.1 0.2 6.1 2.2 0.8 8.5 0.4 0.6 1.0 2.6 1.7 0.4 0.5 0.9 MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789920-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 62.4;stomach 1: 27.2" "Cell line enhanced" "Detected in some" "BJ hTERT+: 88.1;HBF TERT88: 87.3;HUVEC TERT2: 229.4;WM-115: 113.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA004920 Approved Vesicles "Secreted to extracellular matrix" 430000 Vesicles "HPA004920: " "unprognostic (4.11e-3)" "prognostic unfavourable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavourable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavourable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" 0.2 0.1 0.3 12.3 0.3 0.0 0.9 0.3 0.3 0.3 2.7 0.3 0.2 3.2 4.8 0.2 3.3 0.1 62.4 0.4 0.2 0.1 0.7 1.3 4.7 0.2 0.2 0.2 0.2 1.6 0.0 0.2 8.6 0.5 0.7 3.0 0.3 2.0 0.2 0.2 0.3 8.8 0.2 0.4 1.8 27.2 2.2 0.2 0.4 0.3 1.3 0.9 11.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.9 88.1 36.0 9.4 0.7 0.0 0.0 0.4 21.1 0.3 0.0 12.3 87.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 37.0 3.1 229.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 11.9 29.9 0.0 1.3 0.1 0.0 0.0 0.0 0.7 0.0 113.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.3 0.3 0.3 0.3 0.2 0.1 0.2 0.2 0.5 0.2 MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770503-102780628 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "endometrium 1: 89.4" "Cell line enhanced" "Detected in some" "BJ: 12.3;HUVEC TERT2: 15.8;SCLC-21H: 5.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 102.2" "Region enriched" "Detected in single" 9 "pons and medulla: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (8.76e-2)" "unprognostic (3.38e-1)" "unprognostic (1.98e-3)" "unprognostic (2.72e-3)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (5.67e-8)" "unprognostic (2.08e-3)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (6.99e-5)" "unprognostic (2.66e-2)" "unprognostic (7.98e-2)" "unprognostic (5.46e-2)" "prognostic favourable (7.12e-4)" 0.1 0.1 0.0 2.6 0.2 0.1 0.1 0.0 0.3 1.7 0.5 0.0 0.0 0.4 89.4 0.1 0.2 0.1 0.5 0.1 0.0 0.1 0.1 3.6 11.0 0.1 0.0 0.0 0.5 0.3 0.1 0.9 19.8 2.8 3.2 0.2 0.0 2.9 0.1 0.1 0.1 0.7 0.1 0.0 0.2 3.3 0.5 0.0 1.2 0.1 0.0 1.9 0.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.2 12.3 0.7 0.1 0.1 0.3 0.0 0.0 3.6 1.9 2.8 0.0 1.4 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.6 15.8 0.7 0.0 0.0 0.0 0.0 0.3 2.9 1.7 0.0 0.0 0.0 0.0 0.7 5.0 0.0 2.5 0.0 0.0 0.0 0.0 2.0 3.8 1.2 0.4 0.5 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 2.8 0.0 MMP11 STMY3 ENSG00000099953 "Matrix metallopeptidase 11" P24347 22 23768226-23784316 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "endometrium 1: 44.1;placenta: 119.6" "Cell line enhanced" "Detected in some" "AN3-CA: 18.9;BJ hTERT+: 5.1;REH: 7.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 7.8" "Group enriched" "Detected in many" 5 "B-cells: 2.4;dendritic cells: 7.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002593, HPA068864" Approved "Secreted to extracellular matrix" "CAB002593: , HPA068864: " "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.84e-3)" "unprognostic (2.77e-2)" "unprognostic (6.73e-2)" "unprognostic (2.14e-2)" "unprognostic (5.15e-1)" "unprognostic (2.73e-2)" "unprognostic (2.20e-1)" "unprognostic (1.89e-3)" "unprognostic (7.04e-2)" "prognostic unfavourable (2.62e-4)" "unprognostic (8.05e-2)" "unprognostic (6.78e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-2)" 1.7 0.6 0.2 1.0 0.6 0.1 1.6 1.0 0.5 13.4 1.8 0.4 0.4 1.9 44.1 1.1 0.8 2.2 2.0 3.1 0.5 0.0 1.7 0.5 0.7 1.8 0.4 0.2 7.7 1.1 0.2 0.3 119.6 0.5 1.4 1.0 0.8 2.5 0.4 0.5 2.0 4.0 2.7 0.3 0.9 0.7 3.4 0.2 2.6 0.5 0.6 0.9 1.6 2.1 2.4 7.8 0.0 0.0 0.0 1.0 0.1 0.1 0.0 2.3 18.9 2.9 4.2 0.0 0.2 5.1 0.6 0.4 0.0 0.6 0.6 3.5 1.3 0.1 1.0 0.0 0.2 0.0 0.3 0.0 0.0 1.0 2.1 0.0 0.0 2.7 0.4 0.5 0.0 3.0 0.3 0.0 0.7 0.1 0.0 0.0 0.7 0.1 7.9 0.0 0.2 0.3 0.0 3.0 5.1 1.9 0.3 0.0 1.8 0.0 1.3 0.3 0.0 0.8 0.0 0.1 0.1 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 2.4 1.0 0.3 0.0 0.0 0.0 7.8 0.0 0.1 0.2 0.6 1.0 0.5 0.5 0.0 0.4 0.2 0.5 0.2 MMP13 CLG3 ENSG00000137745 "Matrix metallopeptidase 13" P45452 11 102942995-102955734 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 12.6;vagina: 10.8" "Group enriched" "Detected in some" 5 "HaCaT: 19.1;PC-3: 7.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 70.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB002742 Supported "Secreted to extracellular matrix" "CAB002742: " "unprognostic (8.98e-3)" "unprognostic (1.54e-1)" "unprognostic (4.75e-2)" "unprognostic (4.57e-2)" "unprognostic (3.05e-2)" "unprognostic (1.59e-3)" "unprognostic (1.32e-1)" "unprognostic (6.35e-3)" "unprognostic (1.69e-1)" "unprognostic (7.55e-3)" "unprognostic (2.24e-1)" "unprognostic (1.73e-8)" "unprognostic (2.12e-2)" "unprognostic (3.14e-1)" "unprognostic (4.14e-2)" "unprognostic (4.33e-2)" 0.5 0.1 0.0 0.8 0.0 1.3 0.4 0.0 0.2 1.3 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 12.6 0.1 0.0 0.0 0.1 0.0 0.0 3.1 0.1 0.1 1.2 0.0 0.0 0.6 0.0 0.0 1.0 0.5 0.0 0.0 0.1 0.1 1.9 0.0 1.4 0.0 0.0 0.1 4.6 10.8 1.0 0.7 2.7 0.5 1.9 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 7.2 0.0 0.0 0.1 0.0 1.9 0.0 0.1 0.1 2.2 0.0 0.0 0.0 0.0 2.7 1.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.7 0.5 0.6 1.3 0.4 1.0 0.5 0.7 0.8 0.3 1.0 0.6 1.1 1.9 1.9 0.3 0.7 0.4 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836557-22849027 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 98.0;HHSteC: 92.7;HSkMC: 94.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" 570000 Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: " "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavourable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavourable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 60.9 10.5 2.4 16.6 4.7 0.2 64.2 2.2 3.2 56.3 35.0 8.2 12.7 12.0 53.1 24.1 47.0 21.9 39.6 17.5 3.4 1.8 16.8 9.0 29.8 16.9 5.8 2.9 39.3 11.2 34.4 4.7 73.5 16.4 39.1 11.3 27.1 24.4 16.7 20.4 37.0 22.9 28.5 20.7 22.5 18.2 26.3 4.6 5.4 22.3 14.6 16.7 52.5 53.9 0.1 0.7 0.0 0.7 0.0 0.0 0.1 7.9 0.1 2.4 0.1 98.0 62.3 45.0 25.1 50.6 7.6 13.6 2.3 29.9 0.1 14.0 26.4 20.3 0.0 26.1 9.8 0.1 0.1 3.7 0.1 0.5 92.7 0.0 0.1 94.2 15.8 31.7 27.2 46.0 0.1 0.2 17.9 0.1 0.0 9.0 1.5 4.3 0.3 8.6 0.0 6.9 13.7 0.0 0.0 16.4 0.0 54.4 0.1 8.1 40.7 61.9 5.3 18.0 28.6 0.1 0.1 0.1 37.7 0.0 35.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 4.7 2.2 3.2 3.4 1.8 5.8 2.9 16.4 4.6 MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025566-58046901 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.2" "Cell line enhanced" "Detected in many" "BEWO: 36.8;Hep G2: 19.1;SK-BR-3: 18.5;WM-115: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 30 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 30 "dendritic cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: " "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favourable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favourable (3.08e-4)" 5.9 2.3 2.0 5.5 3.0 0.1 7.7 3.7 7.2 3.3 19.5 4.2 16.3 22.6 2.9 1.7 2.5 3.6 15.9 17.6 2.3 3.7 8.4 26.4 6.1 2.0 2.5 2.2 2.1 10.3 7.3 5.2 28.5 10.4 3.6 8.2 9.5 4.7 14.7 3.4 2.3 43.2 3.4 3.4 5.2 14.7 28.0 2.1 1.1 26.8 2.5 2.2 3.3 4.2 0.0 2.9 0.0 0.0 0.0 0.0 0.0 5.7 4.3 2.3 11.8 2.4 0.1 36.8 0.5 0.3 2.1 0.4 3.4 14.8 0.0 7.0 0.6 8.1 1.9 1.7 0.6 0.0 3.9 0.0 1.9 19.1 3.1 0.1 7.7 1.2 3.0 0.3 0.9 1.4 4.7 0.0 0.7 2.8 0.2 0.9 6.7 1.2 2.8 0.3 3.1 6.5 2.1 0.6 4.1 7.7 18.5 3.5 2.0 3.1 1.3 0.1 3.7 1.4 0.5 0.0 0.0 0.1 0.7 0.9 30.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 2.0 3.0 3.7 7.2 2.3 3.7 2.5 2.2 10.4 2.1 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032009-88328025 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9" "Cell line enhanced" "Detected in many" "AN3-CA: 20.0;HUVEC TERT2: 8.7;SH-SY5Y: 11.1;U-138 MG: 9.5;WM-115: 19.5" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 2.4 1.3 11.0 1.4 6.8 0.5 4.9 8.3 15.9 5.3 2.2 2.9 0.7 0.8 4.9 2.1 1.7 2.1 7.3 2.7 8.7 6.9 0.8 0.9 1.0 1.0 5.5 9.1 3.3 2.1 1.5 1.7 3.0 6.3 3.2 1.7 0.6 1.2 2.4 0.7 1.1 1.3 4.0 4.6 1.5 1.4 1.5 5.5 0.0 3.2 0.7 1.0 2.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.4 20.0 0.7 1.4 0.0 7.3 1.0 2.1 1.2 0.0 0.0 0.0 0.0 3.3 0.0 3.9 0.0 2.5 0.0 2.3 0.0 0.0 0.0 1.7 0.0 0.3 1.0 0.0 3.0 0.9 8.7 0.0 0.7 1.1 0.0 0.0 0.0 1.1 2.0 0.2 0.4 0.0 0.4 0.0 0.1 11.1 0.0 0.0 0.1 0.8 0.0 4.8 9.5 5.4 0.1 2.7 0.0 0.0 0.0 3.8 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 6.8 8.3 14.1 8.7 6.9 5.5 9.1 6.3 5.5 MMP19 "MMP18, RASI-1" ENSG00000123342 "Matrix metallopeptidase 19" Q99542 12 55835433-55842966 "Disease related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins" "Angiogenesis, Collagen degradation, Differentiation" "Developmental protein, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 60.7" "Cell line enriched" "Detected in many" 6 "BEWO: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 16 "classical monocyte: 3.2;myeloid DC: 1.0" "Group enriched" "Detected in many" 16 "dendritic cells: 1.0;monocytes: 3.2" "Region enriched" "Detected in single" 6 "olfactory region: 8.8" "Low region specificity" "Detected in all" HPA070804 Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" 800000 "Endoplasmic reticulum, Vesicles" "HPA070804: " "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (2.28e-2)" "unprognostic (2.42e-1)" "unprognostic (4.77e-3)" "unprognostic (4.77e-3)" "unprognostic (2.01e-2)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (2.09e-1)" "prognostic unfavourable (8.56e-9)" "unprognostic (5.06e-3)" "unprognostic (1.28e-3)" "unprognostic (2.73e-2)" "unprognostic (4.00e-2)" 60.7 1.9 0.2 10.9 0.7 0.0 9.9 0.2 0.5 7.6 3.9 0.4 1.4 0.8 12.7 6.0 3.6 11.8 30.3 4.7 0.6 0.1 4.1 3.0 14.0 15.5 0.5 0.2 7.4 8.1 0.0 0.5 24.5 1.0 2.9 2.8 3.1 2.0 3.5 2.1 2.7 4.1 7.7 0.8 27.4 5.0 2.9 0.2 2.7 3.3 1.8 7.1 5.9 3.5 0.0 1.0 0.1 3.2 0.0 0.0 0.6 0.8 0.0 0.0 0.0 6.2 7.9 55.9 5.9 6.9 2.4 2.8 0.3 0.2 0.0 0.0 8.2 0.0 0.0 1.8 3.3 0.3 0.0 0.0 0.0 0.1 5.1 0.0 0.2 8.2 0.2 1.5 1.5 0.4 0.1 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 1.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 9.5 1.5 3.3 0.0 0.2 0.0 0.0 0.0 4.3 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.7 0.2 0.5 0.6 0.1 0.5 0.2 1.0 0.2 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 335.4;ASC TERT1: 97.7;HSkMC: 83.3;U-138 MG: 91.2;U-87 MG: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" 160000000 Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 197.5 9.0 1.2 13.2 1.6 0.0 136.4 0.8 1.4 74.3 74.4 2.4 36.9 5.6 85.0 123.0 52.3 25.7 115.4 54.0 0.9 0.5 9.4 3.5 38.9 3.9 1.5 1.1 71.0 6.5 0.7 2.2 58.9 2.2 66.8 18.7 36.4 18.6 20.4 68.6 68.2 22.6 57.1 1.8 12.4 20.5 57.0 1.1 1.3 20.6 31.8 9.1 84.1 105.3 0.0 0.0 0.9 0.7 0.0 0.0 0.0 0.3 0.2 11.1 0.1 335.4 97.7 18.2 28.7 65.9 5.8 4.6 0.0 0.1 0.0 23.1 50.5 3.1 0.0 0.2 3.3 0.0 0.0 0.0 0.7 0.1 31.7 0.0 0.8 83.3 0.0 29.8 0.2 37.4 0.0 0.1 19.3 0.0 0.0 0.4 8.8 0.0 0.0 2.6 0.0 0.9 0.4 0.1 20.2 5.3 0.0 0.1 0.0 2.0 52.7 91.2 8.7 17.5 3.7 0.0 0.0 0.1 106.8 1.5 16.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 1.2 1.6 0.8 1.4 0.9 0.5 1.5 1.1 2.2 1.1 MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226654-35277000 "Enzymes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 38.5" "Cell line enhanced" "Detected in some" "A549: 19.6;CACO-2: 29.9;EFO-21: 8.8;RPTEC TERT1: 13.5;U-2 OS: 10.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 38.5" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 91.3" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (4.51e-4)" "unprognostic (2.47e-2)" "unprognostic (7.61e-3)" "unprognostic (1.22e-1)" "unprognostic (4.59e-2)" "unprognostic (2.32e-2)" "unprognostic (8.82e-2)" "unprognostic (9.20e-3)" "unprognostic (7.12e-2)" "prognostic favourable (8.17e-11)" "unprognostic (3.32e-2)" "unprognostic (5.63e-2)" "unprognostic (1.69e-2)" "unprognostic (9.90e-4)" 1.6 1.3 4.0 0.4 7.8 0.6 0.4 38.5 8.9 0.7 0.3 1.3 0.2 2.8 1.6 0.9 0.2 2.8 0.6 1.0 2.7 3.2 8.6 0.9 6.1 0.3 1.8 1.5 0.9 8.0 0.0 3.8 0.6 1.7 2.2 0.1 0.5 0.4 6.0 0.2 1.5 1.7 2.5 0.9 0.6 0.7 0.4 1.4 0.2 0.8 0.2 0.2 0.5 0.2 0.8 0.4 2.2 0.8 0.6 1.2 0.3 0.3 19.6 0.0 0.1 0.1 0.0 0.6 1.1 1.2 2.1 1.1 29.9 5.3 0.0 8.8 1.3 0.3 4.6 0.0 0.9 0.1 0.2 1.0 0.5 0.3 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.2 0.1 0.1 7.5 1.3 0.0 0.1 0.0 13.5 0.1 7.8 5.4 1.4 0.5 0.2 0.3 0.1 0.3 4.2 10.1 1.0 0.4 0.1 0.1 0.0 0.9 0.1 0.6 1.0 0.6 0.1 1.0 0.7 1.2 0.6 0.7 0.8 0.4 0.8 0.6 0.6 2.2 0.6 0.8 0.2 0.0 0.3 4.0 7.8 38.5 5.3 2.7 3.2 1.8 1.5 1.7 1.4 MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046681-3060726 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 17.6;bone marrow: 25.6;lymphoid tissue: 54.1" "Cell line enriched" "Detected in some" 12 "HMC-1: 49.3" "Cancer enhanced" "Detected in many" "testis cancer: 7.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "basophil: 10.2;eosinophil: 6.0;neutrophil: 17.6" "Lineage enriched" "Detected in many" 10 "granulocytes: 17.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB025177 Uncertain "Secreted to blood" "CAB025177: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favourable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" 4.0 0.3 0.6 12.3 0.4 25.6 0.8 0.5 0.6 0.8 1.1 0.2 0.0 1.0 0.4 0.5 0.8 3.8 1.1 2.8 0.5 0.4 0.7 2.5 10.7 54.1 1.8 0.0 0.6 0.8 0.0 0.5 2.0 1.1 0.6 1.0 1.0 0.9 0.0 2.4 0.6 1.8 0.5 0.4 43.9 1.1 0.7 0.5 4.1 0.7 0.9 4.2 1.5 2.5 0.0 0.3 17.6 0.2 1.7 0.5 0.1 0.2 0.1 0.6 1.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.6 0.3 0.0 0.0 3.9 0.8 0.1 0.1 0.0 0.0 0.1 49.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 3.0 1.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 3.5 0.1 0.1 0.4 0.1 0.0 1.2 0.1 0.1 0.0 0.9 0.1 10.2 0.2 6.0 0.3 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.3 0.2 17.6 1.7 0.0 0.3 0.3 0.1 0.6 0.4 0.5 0.6 0.5 0.4 1.8 0.0 1.1 0.5 MMP27 ENSG00000137675 "Matrix metallopeptidase 27" Q9H306 11 102691487-102705806 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 10.4;tongue: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "neutrophil: 1.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA069097 Approved "Intracellular and membrane" "HPA069097: " "unprognostic (3.99e-2)" "unprognostic (2.37e-4)" "unprognostic (1.25e-3)" "unprognostic (1.63e-1)" "unprognostic (4.60e-1)" 3.2 0.0 0.0 0.0 0.5 2.4 10.4 0.0 0.0 1.5 0.8 0.0 0.0 0.3 0.9 4.7 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 5.1 0.0 0.8 5.4 2.6 2.0 0.0 0.1 0.4 0.4 0.0 0.9 0.1 10.0 2.2 0.4 0.3 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 9 "HaCaT: 28.1" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 7.2;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in many" 5 "T-cells: 7.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057288, HPA057890" Approved "Nucleoplasm,Focal adhesion sites" "Secreted to extracellular matrix" Nucleoplasm "Focal adhesion sites" "HPA057288: , HPA057890: " "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavourable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" 8.0 1.6 1.8 2.7 3.7 0.5 4.3 0.0 5.1 1.7 7.3 1.6 1.4 3.0 3.2 4.8 4.3 1.5 12.3 0.5 2.8 0.8 0.2 10.3 0.4 0.0 2.9 0.1 1.3 0.5 0.0 0.7 1.3 2.9 4.1 2.7 0.1 2.1 0.6 4.5 9.3 4.3 0.2 0.6 7.2 13.4 0.2 0.0 4.2 4.4 2.5 5.5 2.2 1.1 1.5 0.1 0.2 1.3 7.2 0.9 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.7 0.0 28.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.5 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.2 0.0 0.2 0.6 0.0 0.0 0.0 1.6 0.2 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 2.0 1.1 0.4 1.7 0.1 0.9 7.2 5.9 0.1 1.3 0.2 1.5 0.0 0.9 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843803 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 177.5;salivary gland: 73.4" "Group enriched" "Detected in some" 17 "BJ: 98.9;BJ hTERT+: 269.1;fHDF/TERT166: 116.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" 170000 Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavourable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavourable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 19.1 0.0 0.2 14.4 0.3 0.0 6.9 0.2 0.5 0.2 1.5 0.3 0.2 1.8 28.3 177.5 0.2 0.0 1.4 0.2 0.2 0.0 0.3 0.5 0.4 0.2 0.2 0.2 0.3 0.2 0.0 0.2 0.2 0.2 1.2 1.7 0.2 73.4 1.5 7.3 12.6 0.7 5.9 0.2 0.2 2.8 1.4 0.2 0.2 0.6 1.5 0.9 7.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.9 269.1 1.7 0.5 0.0 0.0 0.0 0.0 116.5 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 7.9 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.2 0.8 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.5 0.2 0.0 0.2 0.2 0.2 0.2 MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530753 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 93.0;kidney: 129.5;salivary gland: 79.3" "Cell line enhanced" "Detected in some" "A549: 22.6;CAPAN-2: 126.5;EFO-21: 30.0;RPTEC TERT1: 54.7" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Region enriched" "Detected in single" 5 "pons and medulla: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: " "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavourable (2.53e-4)" "prognostic unfavourable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" 6.8 0.2 0.2 1.2 0.2 0.0 28.8 0.2 0.2 5.2 0.2 0.2 2.1 0.0 17.2 12.3 3.3 16.4 93.0 0.2 0.2 0.2 129.5 1.4 5.0 0.9 0.2 0.2 3.9 23.5 0.0 0.7 2.7 1.3 42.0 0.0 0.2 79.3 6.7 0.2 7.8 0.3 0.5 0.2 0.2 0.9 9.4 0.2 1.2 0.3 1.4 4.5 19.9 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 126.5 0.0 30.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 1.3 0.2 MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711795-102727050 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "bone marrow: 119.3" "Cell line enriched" "Detected in some" 8 "WM-115: 39.2" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Region enhanced" "Detected in single" "cerebral cortex: 1.7" "Group enriched" "Detected in some" 32 "neutrophil: 1.4;non-classical monocyte: 4.9" "Group enriched" "Detected in many" 32 "granulocytes: 1.4;monocytes: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA022935" Enhanced "Secreted to extracellular matrix" 83000 "HPA021221: AB_1854043, HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" 1.9 0.1 0.2 0.2 0.4 119.3 0.3 0.1 1.7 0.1 0.2 0.0 0.0 0.1 0.6 0.1 0.1 0.1 0.1 9.0 0.2 0.3 0.4 0.8 12.6 2.6 0.3 0.0 0.9 0.9 0.1 0.6 1.4 0.2 0.1 0.1 0.1 0.3 0.1 0.6 0.3 0.1 0.2 0.3 18.7 0.2 0.1 0.1 5.2 1.9 0.0 0.1 0.2 7.6 0.0 0.0 1.4 4.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.9 0.0 0.0 1.7 0.2 0.4 0.1 1.7 0.2 0.3 0.3 0.0 0.2 0.1 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 64.0;blood: 63.2;bone marrow: 89.4;lymphoid tissue: 80.1" "Cell line enriched" "Detected in some" 12 "NB-4: 87.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 141 "neutrophil: 63.2" "Lineage enriched" "Detected in single" 339 "granulocytes: 63.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" 57000000 Cytosol "CAB000348: , CAB068199: , CAB068200: , CAB068201: , HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favourable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavourable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavourable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 64.0 0.5 0.6 38.6 0.7 89.4 4.3 0.4 0.6 0.8 1.2 0.1 0.0 2.8 0.6 0.2 0.9 1.5 0.6 4.0 0.5 0.6 1.4 2.0 13.3 80.1 0.6 0.0 2.7 1.4 0.0 0.8 2.6 0.5 0.6 0.8 0.5 12.5 0.0 1.3 1.3 4.2 0.3 0.5 53.7 2.5 2.7 0.0 23.6 1.3 2.3 44.5 4.5 2.9 0.0 0.0 63.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 7.3 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 87.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 2.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.4 0.6 0.5 0.6 0.6 0.0 0.5 0.0 MOCOS "FLJ20733, HMCS, MOS" ENSG00000075643 "Molybdenum cofactor sulfurase" Q96EN8 18 36187519-36272157 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.0;liver: 36.6" "Cell line enhanced" "Detected in many" "hTCEpi: 20.4;hTERT-HME1: 25.1;SiHa: 26.9;SK-MEL-30: 18.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039412, HPA047958" Uncertain Supported Mitochondria,Cytosol Mitochondria Cytosol "HPA039412: , HPA047958: " "unprognostic (3.07e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (3.18e-3)" "unprognostic (2.55e-1)" "unprognostic (1.97e-1)" "prognostic unfavourable (3.55e-4)" "unprognostic (5.84e-2)" "unprognostic (1.33e-1)" "prognostic unfavourable (1.29e-4)" "unprognostic (2.91e-2)" "prognostic unfavourable (3.03e-12)" "unprognostic (8.98e-2)" "unprognostic (2.37e-1)" "unprognostic (4.09e-1)" "unprognostic (6.35e-2)" 3.7 12.7 0.6 1.6 0.5 0.2 6.4 0.4 0.4 1.4 10.4 0.7 8.0 6.7 1.3 4.6 4.8 1.9 5.8 1.3 0.4 0.5 1.7 36.6 1.8 0.2 0.4 0.1 17.2 3.2 1.1 9.4 11.2 2.2 2.8 1.8 2.1 2.5 7.2 1.3 2.6 33.0 1.0 0.4 0.7 1.7 1.3 0.2 0.0 1.2 2.9 3.5 2.6 1.7 0.4 0.3 1.9 0.3 1.1 0.3 0.1 6.8 2.3 0.1 0.0 2.2 2.8 1.4 4.0 2.2 1.9 5.0 1.5 2.1 0.0 1.2 6.5 4.2 1.4 6.3 2.7 1.1 1.1 0.1 6.8 5.6 7.5 0.0 1.9 4.4 20.4 7.6 25.1 0.3 2.3 0.0 3.1 1.7 0.0 0.0 0.4 2.0 0.0 0.0 0.0 2.7 9.0 0.0 0.6 26.9 1.7 18.7 1.2 0.1 1.3 1.5 1.9 3.3 0.6 0.0 0.0 0.0 3.9 0.0 0.6 1.7 0.3 0.3 0.3 0.2 0.2 0.3 0.2 0.3 0.1 0.4 0.2 0.3 1.9 1.1 0.2 0.3 0.1 0.1 0.6 0.5 0.4 0.4 0.4 0.5 0.4 0.1 2.2 0.2 MOCS1 MOCOD ENSG00000124615 "Molybdenum cofactor synthesis 1" Q9NZB8 6 39899578-39934551 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 26.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.5" "Group enriched" "Detected in many" 9 "NK-cells: 1.5;T-cells: 2.9" "Low region specificity" "Detected in all" "HPA045783, HPA058177, HPA075505" Uncertain Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA045783: AB_10960058, HPA058177: , HPA075505: " "unprognostic (1.22e-1)" "prognostic unfavourable (1.07e-5)" "unprognostic (3.26e-2)" "unprognostic (1.44e-1)" "unprognostic (9.03e-2)" "unprognostic (1.99e-1)" "unprognostic (2.61e-2)" "unprognostic (4.85e-2)" "unprognostic (3.14e-2)" "unprognostic (1.08e-1)" "prognostic favourable (6.07e-5)" "unprognostic (5.34e-3)" "unprognostic (1.21e-1)" "unprognostic (3.97e-3)" "unprognostic (2.78e-1)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" 26.6 9.6 4.6 5.3 7.9 0.2 27.1 5.9 8.7 6.4 17.5 10.5 5.0 15.4 10.1 8.7 6.9 7.9 8.0 18.0 6.2 2.3 17.5 34.9 19.6 9.2 9.5 6.2 9.0 10.9 4.5 6.3 30.2 7.0 6.7 5.2 11.2 5.9 7.6 19.9 7.1 13.1 8.9 7.1 3.5 6.5 4.0 7.6 0.2 15.4 5.9 3.1 9.7 7.7 0.0 0.1 0.0 0.2 1.5 2.9 0.8 0.0 1.4 5.0 8.0 13.5 5.2 10.1 5.4 9.9 7.8 7.1 26.4 0.1 0.0 5.7 5.4 0.4 6.0 6.6 6.1 0.0 5.4 0.0 0.0 8.3 8.6 0.0 2.2 9.1 2.4 5.4 3.0 6.7 5.4 0.5 7.9 3.4 10.2 0.0 4.5 2.9 0.0 3.8 0.8 4.8 5.1 4.1 5.2 0.0 3.2 4.6 3.4 1.0 10.4 7.9 6.8 5.1 2.8 0.0 1.0 0.0 0.9 0.0 2.8 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.6 0.5 0.1 0.0 2.9 2.5 0.0 1.5 0.2 0.0 0.0 0.8 4.6 7.9 5.9 8.7 6.2 2.3 9.5 6.2 7.0 7.6 MOCS2 MOCO1 ENSG00000164172 "Molybdenum cofactor synthesis 2" "O96007, O96033" 5 53095679-53110063 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037679, HPA037680" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA037679: AB_2675604, HPA037680: AB_10673635" "unprognostic (3.27e-1)" "unprognostic (3.11e-2)" "unprognostic (2.82e-1)" "unprognostic (8.37e-3)" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.60e-2)" "unprognostic (1.33e-1)" "unprognostic (6.66e-2)" "unprognostic (7.59e-2)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" "prognostic favourable (3.68e-6)" "unprognostic (1.04e-1)" "unprognostic (1.04e-2)" "unprognostic (2.04e-1)" "unprognostic (5.86e-2)" 18.1 34.6 41.5 9.8 38.0 4.0 19.6 21.7 41.8 16.0 17.1 20.7 10.4 17.6 14.8 28.2 17.0 12.9 15.9 39.9 36.7 32.1 49.7 52.0 13.1 11.4 30.0 22.4 21.2 18.4 30.4 23.3 16.2 28.7 18.6 14.9 17.2 21.2 20.8 38.3 8.9 17.6 16.1 27.1 10.7 16.6 11.0 20.0 8.2 31.5 19.4 11.2 16.9 15.4 16.9 12.5 6.3 10.9 17.3 25.8 12.9 20.1 16.6 12.0 28.6 24.6 22.7 15.2 24.8 26.1 22.2 26.3 22.6 15.2 20.7 37.5 19.6 12.3 24.0 25.5 35.0 5.2 23.4 15.9 16.3 20.4 25.3 17.1 11.9 18.0 12.8 25.2 22.4 23.8 15.3 11.3 36.9 30.0 18.5 9.8 10.6 34.5 9.3 25.8 18.8 38.4 15.4 8.9 10.3 18.1 14.8 18.6 28.6 4.4 15.2 21.3 22.0 18.9 31.9 13.2 19.6 23.4 30.5 4.9 32.8 5.2 9.2 6.3 16.9 10.9 20.2 16.5 19.0 19.2 12.5 16.9 25.8 22.2 1.7 17.3 9.8 11.4 18.3 12.9 41.5 38.0 21.7 41.8 36.7 32.1 30.0 22.4 28.7 20.0 MOCS3 "dJ914P20.3, UBA4" ENSG00000124217 "Molybdenum cofactor synthesis 3" O95396 20 50958826-50963931 "Enzymes, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis, tRNA processing" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027556 Uncertain "HPA027556: " "unprognostic (1.29e-1)" "unprognostic (2.57e-1)" "unprognostic (3.16e-1)" "prognostic unfavourable (5.82e-4)" "unprognostic (2.11e-1)" "unprognostic (1.17e-1)" "prognostic unfavourable (1.39e-4)" "unprognostic (3.76e-1)" "unprognostic (3.19e-1)" "unprognostic (1.33e-2)" "unprognostic (8.67e-3)" "unprognostic (4.90e-2)" "prognostic favourable (7.55e-4)" "unprognostic (8.39e-2)" "unprognostic (8.48e-2)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" 5.3 9.2 5.4 6.4 9.0 3.4 6.6 5.6 13.7 7.4 6.7 7.0 8.8 7.1 9.0 9.9 9.8 9.3 8.7 7.2 5.3 6.6 6.9 9.8 5.3 10.5 4.7 6.3 10.2 7.9 6.2 7.7 11.0 6.1 7.6 5.8 7.2 7.7 6.8 10.3 8.4 8.1 6.0 3.7 9.5 7.3 19.4 3.3 12.1 9.7 8.8 8.8 8.3 5.7 8.9 8.6 6.7 9.7 7.5 11.2 6.5 3.4 5.8 3.6 5.0 5.1 4.2 6.6 4.0 4.3 10.1 4.4 12.4 5.0 5.1 5.3 3.6 9.8 3.7 9.9 6.5 1.8 3.9 4.0 4.8 7.1 5.3 4.0 4.3 4.7 8.4 4.1 4.1 3.4 5.8 3.1 3.7 5.5 6.5 4.8 5.3 10.0 2.6 5.6 4.4 4.0 5.3 5.2 6.1 6.2 20.2 6.4 8.4 7.7 4.1 7.7 4.4 4.1 4.3 7.7 6.9 2.2 6.9 2.4 3.2 4.9 7.5 6.7 6.4 6.8 8.1 8.9 6.6 7.0 8.6 7.0 11.2 8.7 4.1 7.5 9.7 4.8 10.0 6.5 5.4 9.0 5.6 13.7 5.3 6.6 4.7 6.3 6.1 3.3 MOGAT1 "DGAT2L, DGAT2L1, MGAT1" ENSG00000124003 "Monoacylglycerol O-acyltransferase 1" Q96PD6 2 222671786-222709930 "Enzymes, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "gallbladder: 40.9" "Cell line enhanced" "Detected in single" "Hep G2: 1.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.9" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "plasmacytoid DC: 3.4" "Lineage enriched" "Detected in single" 7 "dendritic cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA049944 Uncertain "HPA049944: " "unprognostic (6.32e-2)" "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (4.28e-3)" "unprognostic (4.39e-2)" "unprognostic (4.32e-2)" "unprognostic (9.44e-2)" "unprognostic (1.91e-1)" "unprognostic (8.59e-2)" "unprognostic (3.07e-3)" "unprognostic (4.99e-2)" "unprognostic (3.89e-1)" "unprognostic (9.03e-3)" 2.3 0.1 0.6 0.1 0.5 0.1 1.3 0.2 0.9 0.3 0.6 0.5 0.2 0.0 1.0 1.1 0.5 0.1 40.9 0.8 0.5 0.2 5.7 7.6 1.1 0.3 0.2 0.9 0.1 1.5 2.3 0.4 0.0 0.9 0.2 0.1 0.0 1.4 2.6 0.5 1.6 0.2 0.1 0.3 0.1 1.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 3.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 1.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.0 0.5 0.3 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.6 0.5 0.2 0.9 0.5 0.2 0.2 0.9 0.9 0.0 MOGAT2 "DGAT2L5, FLJ22644, MGAT2" ENSG00000166391 "Monoacylglycerol O-acyltransferase 2" Q3SYC2 11 75717819-75732958 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 90.2;liver: 40.5" "Group enriched" "Detected in some" 7 "Hep G2: 8.4;RPMI-8226: 5.6" "Cancer enhanced" "Detected in many" "liver cancer: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028834 Uncertain "HPA028834: AB_10601865" "unprognostic (5.63e-2)" "unprognostic (2.71e-2)" "unprognostic (6.37e-2)" "unprognostic (6.88e-3)" "unprognostic (1.15e-4)" "unprognostic (2.66e-3)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (4.21e-2)" "unprognostic (3.02e-1)" "unprognostic (1.24e-5)" "unprognostic (2.13e-3)" "unprognostic (1.84e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-3)" 0.1 0.0 0.1 4.8 0.1 0.0 2.1 0.1 0.1 0.2 34.0 0.1 1.4 22.3 0.1 0.1 0.2 0.0 2.6 0.1 0.1 0.0 0.2 40.5 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 7.0 0.1 0.4 2.2 0.4 0.9 90.2 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 5.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 MOGAT3 "DC7, DGAT2L2, MGAT3" ENSG00000106384 "Monoacylglycerol O-acyltransferase 3" Q86VF5 7 101195007-101201021 "Enzymes, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 61.6;liver: 16.0" "Group enriched" "Detected in some" 6 "CACO-2: 4.7;Hep G2: 15.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.0;liver cancer: 11.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "neutrophil: 5.3" "Low lineage specificity" "Detected in many" HPA011940 Approved Approved Centrosome Centrosome "HPA011940: AB_1854057" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (7.14e-2)" "unprognostic (6.11e-2)" "unprognostic (3.20e-1)" "unprognostic (9.54e-3)" "unprognostic (9.36e-2)" "unprognostic (3.08e-1)" "unprognostic (1.05e-3)" "unprognostic (1.87e-1)" "unprognostic (1.23e-1)" "unprognostic (9.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.59e-2)" 0.2 0.1 0.2 2.6 0.2 0.4 0.2 0.2 0.2 0.2 17.3 0.2 0.2 19.7 0.2 0.5 0.2 0.1 0.2 0.2 0.2 0.1 0.9 16.0 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 7.1 0.2 0.2 0.2 0.2 0.1 61.6 0.4 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 1.7 1.2 5.3 0.9 1.9 1.2 0.3 0.6 0.2 0.2 0.5 0.0 0.1 0.4 0.6 0.0 0.0 0.0 4.7 1.1 0.3 0.6 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.6 0.6 15.8 0.2 0.5 0.6 0.1 0.1 0.0 0.1 0.1 0.2 0.6 0.1 0.3 0.3 0.5 0.2 0.6 0.3 0.1 0.4 0.7 0.6 0.3 0.3 0.3 0.6 0.1 0.3 0.3 0.8 0.9 0.2 1.0 0.5 0.4 0.2 0.1 1.7 0.6 1.4 2.2 0.9 1.1 1.0 0.7 0.7 1.0 0.8 0.7 0.5 1.7 0.9 1.2 5.3 1.9 0.6 1.2 0.5 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 MOGS "CWH41, DER7, GCS1" ENSG00000115275 "Mannosyl-oligosaccharide glucosidase" Q13724 2 74461057-74465410 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011322, HPA011969" Approved Supported "Endoplasmic reticulum" 88000000 "Endoplasmic reticulum" "HPA011322: , HPA011969: AB_1849579" "unprognostic (5.66e-2)" "unprognostic (1.98e-2)" "prognostic unfavourable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-1)" "prognostic unfavourable (2.34e-6)" "unprognostic (1.48e-2)" "unprognostic (2.66e-2)" "unprognostic (3.32e-2)" "unprognostic (6.21e-2)" "unprognostic (4.36e-1)" "prognostic unfavourable (2.79e-8)" "unprognostic (1.40e-2)" "unprognostic (3.06e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" 15.8 12.8 8.7 15.2 10.6 8.5 13.1 11.3 12.1 13.9 19.4 10.8 24.9 36.5 14.2 15.8 15.5 13.4 16.4 11.2 7.7 6.1 14.8 40.5 17.2 15.6 9.2 7.9 14.2 30.6 20.4 15.7 35.8 8.3 15.9 11.2 11.7 24.5 25.3 14.1 17.4 35.8 9.8 7.1 22.4 22.3 11.9 8.1 17.6 18.9 11.4 19.5 14.1 12.9 3.9 3.4 2.3 4.4 12.7 5.1 2.5 22.1 19.7 13.1 12.6 27.0 19.1 40.1 18.2 26.3 27.6 26.6 36.0 23.7 24.0 16.2 18.3 22.3 19.7 20.5 17.1 20.7 19.1 11.2 12.8 27.6 22.3 26.3 22.6 11.1 32.9 19.5 19.1 30.9 19.5 23.3 12.1 27.6 14.2 20.2 17.3 11.0 16.3 29.1 31.1 15.0 13.8 10.8 14.1 8.6 36.1 23.6 17.5 14.2 22.0 12.7 22.2 18.4 24.0 36.0 14.8 10.6 20.0 21.5 17.2 2.3 4.0 1.1 5.0 2.5 5.1 2.5 4.2 4.5 3.4 3.9 3.7 2.4 0.7 12.7 4.4 3.2 3.8 2.5 8.7 10.6 11.3 12.1 7.7 6.1 9.2 7.9 8.3 8.1 MOK "RAGE, RAGE1, STK30" ENSG00000080823 "MOK protein kinase" Q9UQ07 14 102224500-102305200 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "testis: 45.0" "Cell line enhanced" "Detected in many" "HBF TERT88: 28.0;hTEC/SVTERT24-B: 71.2;NB-4: 88.6;U-138 MG: 37.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 10.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027292 Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA027292: AB_10600989" "unprognostic (8.16e-2)" "unprognostic (1.82e-1)" "unprognostic (6.68e-2)" "unprognostic (6.05e-3)" "unprognostic (1.34e-2)" "unprognostic (1.81e-2)" "unprognostic (4.43e-2)" "unprognostic (3.49e-4)" "unprognostic (2.19e-1)" "unprognostic (2.03e-2)" "unprognostic (2.93e-1)" "unprognostic (3.01e-3)" "unprognostic (5.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-2)" "unprognostic (2.48e-1)" 5.9 6.8 12.9 2.7 17.3 3.7 7.8 9.7 15.9 7.6 3.6 8.7 6.2 4.7 7.6 10.2 3.9 26.4 6.4 8.3 13.5 10.2 7.7 3.6 6.1 2.5 6.0 13.7 12.4 8.6 9.4 22.1 3.6 16.6 5.1 3.0 15.2 6.1 5.4 1.9 8.6 4.1 5.9 6.2 3.8 11.7 45.0 6.2 0.4 11.7 2.3 2.2 6.2 3.9 0.7 3.9 0.9 1.1 10.6 2.4 1.3 3.3 3.0 0.4 1.7 0.7 2.5 0.7 6.8 2.0 9.9 11.9 0.2 8.3 2.5 0.5 1.3 0.7 0.6 3.5 28.0 2.8 2.5 0.6 0.3 2.2 3.0 0.2 3.3 2.1 0.9 71.2 6.6 0.3 0.6 0.1 6.4 2.2 0.2 88.6 0.1 7.2 0.4 0.1 0.0 4.0 0.1 1.1 0.7 1.2 0.4 19.2 2.0 0.2 0.2 37.6 1.9 1.4 2.1 0.2 0.4 0.2 7.5 0.2 17.0 0.0 1.1 0.0 0.7 0.7 1.2 0.0 0.5 1.9 3.9 0.7 1.1 2.4 0.9 10.6 0.1 0.0 0.0 1.3 12.9 17.3 9.7 15.9 13.5 10.2 6.0 13.7 16.6 6.2 MOV10 "fSAP113, gb110, MGC2948" ENSG00000155363 "Mov10 RISC complex RNA helicase" Q9HCE1 1 112673141-112700746 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031627 Approved Cytosol Cytosol "HPA031627: " "unprognostic (1.44e-2)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" "unprognostic (6.82e-3)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "prognostic unfavourable (3.44e-4)" "unprognostic (9.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.58e-3)" "unprognostic (2.85e-1)" "unprognostic (1.54e-1)" "prognostic unfavourable (1.48e-11)" "unprognostic (4.01e-2)" "unprognostic (3.61e-1)" "unprognostic (1.46e-3)" "unprognostic (1.21e-3)" 12.5 17.0 6.2 12.6 6.9 3.5 15.0 1.9 6.3 11.4 23.1 9.3 12.3 18.8 16.4 12.6 15.8 12.2 15.3 5.8 8.6 5.1 13.3 19.4 9.7 7.7 5.9 5.1 14.5 12.9 13.1 14.1 20.2 8.2 14.0 9.3 13.8 13.5 16.5 3.1 23.2 33.8 9.4 6.3 12.9 10.4 17.7 6.0 14.5 12.1 6.9 10.9 11.0 12.5 1.9 5.6 0.9 9.5 9.9 10.8 5.9 11.8 7.3 4.4 16.8 3.5 10.2 16.5 8.1 19.4 24.1 34.5 13.5 13.1 0.0 5.6 11.2 12.6 16.5 19.6 8.4 13.0 10.0 8.2 10.6 15.2 15.3 3.4 8.1 17.2 6.0 14.6 4.6 20.4 10.8 4.1 7.4 22.0 12.9 2.6 9.8 7.5 23.3 11.0 0.5 11.1 13.0 1.8 6.3 16.9 11.4 13.2 8.9 7.8 12.2 7.5 13.5 5.2 7.2 4.7 1.3 0.0 14.8 7.1 21.4 0.7 2.8 0.5 10.7 8.4 10.8 1.9 9.7 9.7 5.6 1.4 9.4 7.1 0.9 9.9 9.5 0.9 8.2 5.9 6.2 6.9 1.9 6.3 8.6 5.1 5.9 5.1 8.2 6.0 MOV10L1 "CHAMP, DJ402G11.8, DKFZp434B0717" ENSG00000073146 "Mov10 RISC complex RNA helicase like 1" Q9BXT6 22 50089879-50161690 "Enzymes, Predicted intracellular proteins" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 27.7" "Cell line enhanced" "Detected in some" "HHSteC: 3.2;HUVEC TERT2: 15.7;TIME: 7.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019034 Approved "HPA019034: AB_1854070" "unprognostic (1.39e-1)" "unprognostic (2.30e-2)" "unprognostic (1.88e-2)" "unprognostic (7.91e-2)" "unprognostic (4.29e-2)" "unprognostic (4.05e-2)" "unprognostic (1.21e-1)" "unprognostic (2.69e-1)" "unprognostic (9.43e-2)" "unprognostic (7.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.03e-1)" "unprognostic (8.02e-3)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" 0.4 0.1 0.7 0.2 1.5 0.3 0.2 1.3 1.3 0.9 0.8 0.6 0.2 0.1 3.0 2.0 0.4 1.0 1.2 0.3 0.9 0.6 0.3 1.0 0.3 0.2 0.5 1.5 1.8 0.2 0.1 0.4 0.6 2.1 1.0 0.2 0.6 0.2 0.2 0.2 0.3 0.4 1.9 0.7 0.2 0.1 27.7 0.2 0.2 0.5 0.2 0.3 0.4 2.0 0.0 0.0 0.0 0.6 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.5 1.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 3.2 0.0 1.5 0.2 0.0 0.0 0.0 15.7 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 7.2 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 1.5 1.3 1.3 0.9 0.6 0.5 1.5 2.1 0.2 MPG MDG ENSG00000103152 "N-methylpurine DNA glycosylase" P29372 16 77007-85853 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006531 Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006531: AB_1854075" "unprognostic (1.78e-2)" "unprognostic (8.48e-2)" "unprognostic (9.99e-2)" "prognostic favourable (2.82e-5)" "unprognostic (8.54e-2)" "unprognostic (3.27e-1)" "unprognostic (2.75e-2)" "unprognostic (1.63e-1)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (1.85e-2)" "unprognostic (1.83e-2)" "unprognostic (1.39e-2)" "unprognostic (1.86e-3)" "unprognostic (3.88e-2)" "unprognostic (1.86e-2)" "unprognostic (3.26e-1)" 20.8 32.1 18.4 21.1 18.4 25.3 33.2 18.3 32.1 19.5 20.4 12.6 24.6 21.0 22.6 30.5 21.5 18.5 28.5 37.4 16.7 15.1 16.1 32.0 20.1 39.7 15.8 18.2 23.8 36.5 8.0 21.7 19.0 16.5 23.2 7.2 15.2 47.1 24.2 33.6 19.0 19.4 19.2 13.6 25.6 27.3 10.9 11.2 18.3 29.2 22.4 22.8 27.2 25.2 33.5 38.8 27.2 27.4 41.2 31.1 22.4 13.8 20.3 5.5 17.0 10.2 23.3 13.9 20.0 27.6 13.0 14.3 12.8 18.8 9.9 17.5 11.3 17.9 3.8 8.7 2.0 17.0 14.7 6.4 10.4 19.0 29.5 6.7 39.8 22.4 12.2 14.6 6.0 22.6 14.1 17.9 16.9 48.0 11.6 30.9 10.0 22.2 22.2 6.7 37.7 10.8 5.0 4.5 11.6 10.5 11.4 25.1 16.3 34.7 19.8 10.6 13.5 14.4 9.8 17.4 5.9 12.6 19.6 19.4 37.8 14.2 27.4 27.2 22.7 19.2 20.6 33.5 21.8 22.6 28.5 30.6 16.8 17.2 14.0 41.2 15.7 38.8 31.1 22.4 18.4 18.4 18.3 32.1 16.7 15.1 15.8 18.2 16.5 11.2 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" 170000 Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavourable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 13.6 33.3 24.2 11.2 26.2 7.4 14.7 19.2 33.7 16.7 22.6 26.1 15.3 32.6 15.7 26.8 17.1 20.7 13.4 28.8 22.7 22.2 22.5 30.2 10.6 16.2 28.1 28.3 23.2 34.2 24.7 15.0 11.4 37.4 20.6 23.1 18.3 18.6 17.9 33.3 11.7 27.4 16.4 21.7 14.7 14.3 23.5 17.7 16.4 17.1 15.0 16.6 15.6 11.7 12.8 10.2 2.4 7.4 17.7 27.1 12.9 10.4 14.5 12.0 13.6 27.5 13.4 10.5 9.0 14.8 15.5 21.8 14.3 13.9 14.9 19.7 13.1 26.1 23.8 26.3 14.8 11.3 29.8 26.6 13.8 15.3 19.6 12.2 7.9 17.8 6.8 14.6 26.3 21.0 8.9 12.2 20.0 8.9 13.1 5.4 6.6 12.4 13.5 11.3 36.4 18.2 11.9 22.5 9.8 10.5 19.0 11.3 26.1 8.5 9.5 9.3 8.0 6.9 8.7 30.3 17.9 9.7 19.5 17.8 6.7 0.7 7.2 2.4 13.5 7.4 17.5 12.8 18.3 15.4 10.2 12.5 27.1 19.7 1.1 17.7 6.3 8.5 22.7 12.9 24.2 26.2 19.2 33.7 22.7 22.2 28.1 28.3 37.4 17.7 MPND FLJ14981 ENSG00000008382 "MPN domain containing" Q8N594 19 4343527-4360086 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043274, HPA045475" Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA043274: AB_2678403, HPA045475: " "unprognostic (3.16e-2)" "prognostic favourable (2.99e-4)" "unprognostic (4.85e-2)" "prognostic favourable (6.12e-4)" "unprognostic (8.60e-2)" "unprognostic (5.37e-3)" "unprognostic (3.16e-2)" "prognostic favourable (1.55e-4)" "unprognostic (1.23e-1)" "unprognostic (2.87e-2)" "unprognostic (3.94e-3)" "unprognostic (5.18e-2)" "prognostic favourable (7.04e-4)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (5.44e-2)" "unprognostic (9.04e-2)" 7.7 13.7 18.9 14.1 12.3 11.5 8.0 12.1 21.6 6.5 19.9 6.6 15.7 25.9 8.5 7.8 13.8 8.2 11.8 12.1 14.2 11.3 12.8 25.1 14.3 8.5 12.7 20.0 8.7 20.7 14.5 7.2 7.0 11.9 12.1 13.9 11.5 14.3 9.0 17.4 12.5 20.7 9.3 8.9 10.1 12.5 4.2 6.7 13.5 8.6 8.3 10.1 9.3 11.0 3.1 4.5 10.3 6.0 2.4 5.6 1.9 7.9 6.7 11.1 12.6 6.9 3.3 11.3 3.8 3.7 3.2 4.0 12.9 4.1 7.2 12.2 5.0 8.2 5.0 6.7 1.8 8.1 11.3 5.5 9.4 20.8 5.5 7.3 9.9 5.0 4.8 3.5 3.7 9.8 2.9 18.8 4.0 22.9 17.3 6.3 5.0 9.7 14.3 3.4 10.4 8.2 14.0 12.4 12.7 7.0 10.0 5.3 6.7 9.0 3.7 5.1 5.5 31.3 7.7 15.6 9.6 4.7 5.7 4.1 5.9 10.3 5.1 2.4 2.2 6.0 3.4 1.8 2.6 3.1 4.5 3.1 1.7 1.9 1.2 2.4 2.7 4.5 5.6 1.9 18.9 12.3 12.1 21.6 14.2 11.3 12.7 20.0 11.9 6.7 MPO ENSG00000005381 Myeloperoxidase P05164 17 58269856-58280935 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 315.2" "Group enriched" "Detected in some" 93 "HL-60: 212.9;NB-4: 279.1" "Cancer enhanced" "Detected in single" "stomach cancer: 1.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "classical monocyte: 7.6;intermediate monocyte: 3.8;myeloid DC: 3.2;neutrophil: 2.0" "Group enriched" "Detected in many" 30 "dendritic cells: 3.2;granulocytes: 2.0;monocytes: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000059, HPA021147, HPA061464" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" 15000000 Vesicles Nucleoplasm "CAB000059: AB_2335676, HPA021147: AB_1854083, HPA061464: AB_2684531" "unprognostic (1.91e-1)" "unprognostic (9.08e-2)" "unprognostic (4.62e-2)" "unprognostic (2.90e-2)" "unprognostic (2.13e-3)" "unprognostic (2.78e-1)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (6.92e-2)" "unprognostic (8.34e-3)" "unprognostic (4.91e-2)" "unprognostic (3.07e-3)" "unprognostic (2.83e-1)" "unprognostic (1.14e-2)" "unprognostic (8.05e-2)" 0.2 0.1 0.5 0.1 0.8 315.2 0.1 0.4 1.0 0.1 0.1 1.4 0.0 0.1 0.2 0.2 0.1 0.1 0.1 21.5 0.6 0.8 0.1 1.4 6.9 0.8 0.6 0.0 0.6 0.1 0.1 1.0 2.9 0.4 0.2 0.1 0.2 6.3 0.1 0.7 0.5 0.1 0.1 0.4 17.8 0.1 0.4 0.2 19.7 0.6 0.0 0.5 0.1 0.0 0.0 3.2 2.0 7.6 0.0 0.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 212.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 279.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.6 0.0 0.0 3.8 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 2.0 0.0 0.8 0.0 0.1 7.2 0.5 0.8 0.4 1.0 0.6 0.8 0.6 0.0 0.4 0.2 MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029822 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 106.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001240 Enhanced Approved Mitochondria,Cytosol 2800000 Mitochondria Cytosol "HPA001240: AB_1079408" "unprognostic (7.18e-3)" "unprognostic (4.45e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-3)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (7.07e-2)" "unprognostic (2.15e-1)" "unprognostic (2.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-3)" "unprognostic (3.98e-2)" "unprognostic (3.51e-1)" "unprognostic (2.52e-1)" "prognostic favourable (5.89e-4)" 8.7 7.2 4.5 6.8 6.4 10.5 22.7 2.6 5.4 8.8 39.1 8.0 2.8 36.8 6.1 3.0 19.8 4.3 15.3 14.1 4.6 2.3 14.1 106.2 10.3 5.4 8.8 3.8 12.6 20.7 0.7 2.7 4.2 5.6 6.6 5.7 3.8 13.4 3.9 11.5 15.9 33.7 4.8 4.8 4.1 12.8 24.9 7.1 2.1 6.3 6.2 5.1 8.7 11.6 9.6 37.1 18.5 26.5 28.8 16.1 12.5 14.1 16.7 8.2 16.9 9.6 6.0 13.0 7.7 6.9 8.4 11.4 15.9 6.3 22.3 11.2 5.5 9.9 7.1 11.2 1.2 13.4 39.7 8.6 7.3 37.4 30.6 9.2 12.1 10.5 21.9 5.5 5.1 17.0 15.3 6.5 2.3 11.0 0.8 31.5 15.4 17.4 23.9 9.7 16.6 8.5 4.6 4.2 31.6 5.1 8.1 14.7 8.7 15.0 13.1 7.3 20.7 8.0 5.2 11.4 5.3 6.7 2.6 11.3 3.7 15.3 26.5 18.5 11.8 9.4 16.1 9.6 7.7 9.9 37.1 9.6 1.1 4.1 7.9 28.8 4.3 6.0 15.2 12.5 4.5 6.4 2.6 5.4 4.6 2.3 8.8 3.8 5.6 7.1 MRI1 "MGC3207, MRDI, mtnA, Ypr118w" ENSG00000037757 "Methylthioribose-1-phosphate isomerase 1" Q9BV20 19 13764532-13774282 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042744, CAB045988" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" 2600000 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "CAB045988: AB_2145566, HPA042744: " "unprognostic (1.16e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.14e-2)" "unprognostic (1.05e-1)" "unprognostic (3.24e-1)" "unprognostic (1.57e-2)" "unprognostic (4.27e-3)" "unprognostic (1.61e-1)" "unprognostic (8.98e-2)" "unprognostic (1.50e-3)" "unprognostic (1.75e-2)" "unprognostic (1.18e-2)" "unprognostic (1.67e-1)" "unprognostic (1.77e-1)" "unprognostic (1.28e-1)" 14.5 18.5 12.5 21.8 18.3 16.6 16.8 24.5 21.8 21.5 17.2 23.6 23.5 19.0 24.2 21.3 20.7 19.9 17.6 13.5 14.6 12.1 24.4 20.1 15.4 19.5 16.5 14.3 24.0 20.5 21.3 17.3 24.2 17.2 17.8 13.4 18.5 23.4 21.6 13.0 28.6 18.5 13.3 16.6 22.0 19.8 5.0 16.7 20.0 21.8 10.5 18.2 18.1 20.6 5.7 8.9 6.9 5.8 5.0 6.6 3.6 10.5 7.9 3.9 9.4 4.3 8.1 9.7 12.6 7.3 11.4 10.4 8.3 8.5 5.7 5.0 4.7 17.9 18.3 13.0 7.0 10.0 31.7 4.5 12.5 8.9 3.8 13.7 10.6 8.1 7.2 5.8 4.6 10.6 8.7 0.3 4.9 15.5 15.1 8.7 6.5 22.5 14.3 5.3 12.9 5.9 8.3 7.9 7.1 4.6 10.3 9.8 8.0 5.0 6.4 5.9 5.5 20.8 6.1 7.8 8.2 1.7 5.0 15.9 7.0 6.9 5.5 1.9 6.2 5.8 6.0 5.0 5.3 6.6 4.7 5.7 4.3 3.3 4.1 5.0 3.2 8.9 4.8 3.6 12.5 18.3 24.5 21.8 14.6 12.1 16.5 14.3 17.2 16.7 MRPL58 "DS-1, ICT1" ENSG00000167862 "Mitochondrial ribosomal protein L58" Q14197 17 75012670-75021261 "Enzymes, Predicted intracellular proteins, Ribosomal proteins" "Protein biosynthesis" "Hydrolase, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003634 Approved Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA003634: AB_1851388" "unprognostic (2.04e-1)" "unprognostic (1.57e-2)" "unprognostic (1.94e-3)" "unprognostic (7.12e-2)" "unprognostic (3.16e-2)" "unprognostic (4.35e-2)" "unprognostic (1.38e-3)" "unprognostic (1.52e-1)" "unprognostic (2.57e-1)" "unprognostic (3.79e-3)" "unprognostic (4.98e-2)" "unprognostic (2.43e-2)" "prognostic unfavourable (2.09e-4)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.66e-2)" "unprognostic (1.71e-1)" 12.4 23.4 13.9 18.4 14.8 13.7 17.6 18.1 15.7 10.6 15.2 9.8 17.5 13.1 12.5 15.1 19.4 12.5 16.3 31.2 12.2 12.0 25.7 41.7 10.2 15.2 14.3 14.0 10.5 24.2 13.5 9.1 13.9 14.0 13.6 16.3 10.1 17.7 22.5 57.3 16.5 13.4 14.8 12.9 14.6 15.1 7.6 14.0 13.2 14.8 31.2 15.7 14.3 11.6 18.3 28.9 11.2 22.0 20.0 33.5 20.9 26.2 37.1 12.4 14.2 13.3 13.2 17.3 15.6 17.0 32.5 27.7 28.4 16.5 18.3 12.8 15.4 18.8 25.3 26.8 34.4 9.3 30.0 14.3 17.5 23.6 25.2 29.9 9.9 14.3 12.8 21.6 34.6 24.7 23.1 13.4 18.3 32.8 25.8 20.6 9.3 50.3 13.4 22.0 26.6 23.9 19.5 11.5 22.1 13.5 24.7 30.2 32.9 24.8 10.4 17.6 19.3 18.4 29.3 14.0 11.1 20.2 20.1 33.6 14.5 11.2 22.0 10.5 17.3 20.7 14.9 18.3 21.1 17.2 28.9 14.8 15.7 17.6 2.0 20.0 17.4 19.4 33.5 20.9 13.9 14.8 18.1 15.7 12.2 12.0 14.3 14.0 14.0 14.0 MSMO1 "DESP4, ERG25, SC4MOL" ENSG00000052802 "Methylsterol monooxygenase 1" Q15800 4 165327623-165343160 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 171.6" "Cell line enhanced" "Detected in all" "CAPAN-2: 61.6;HBEC3-KT: 61.1;Karpas-707: 69.6;RPTEC TERT1: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056127 Enhanced "HPA056127: " "unprognostic (5.76e-2)" "prognostic unfavourable (2.97e-4)" "unprognostic (3.35e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (7.14e-2)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.28e-1)" "prognostic favourable (9.21e-4)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.54e-1)" "unprognostic (1.40e-1)" 5.0 26.5 17.1 6.7 23.7 3.5 21.5 7.7 29.6 15.6 12.6 22.8 4.0 22.6 6.1 31.5 44.9 7.1 7.4 5.8 18.8 20.8 16.3 171.6 30.0 6.4 13.1 18.6 18.0 7.5 10.9 7.0 7.4 41.1 19.1 10.8 12.1 10.6 4.7 2.2 22.5 20.7 5.7 33.5 4.3 10.3 15.8 12.5 4.3 7.5 17.6 12.9 8.6 17.7 21.2 10.1 6.2 9.8 12.1 20.8 15.8 14.3 3.5 33.8 6.1 16.8 53.8 6.3 5.8 26.4 7.5 20.9 6.7 61.6 7.1 3.5 7.0 11.8 16.9 61.1 8.4 6.0 10.4 3.2 3.6 20.7 33.7 5.8 4.5 33.3 40.2 27.7 17.2 9.7 5.6 69.6 12.4 7.4 5.1 9.4 19.4 3.5 2.7 3.7 21.4 67.1 16.8 6.7 5.0 9.0 13.0 5.4 6.0 7.2 11.1 3.5 6.2 3.1 3.9 12.8 13.5 9.4 7.4 5.9 4.7 6.2 4.6 4.5 19.0 5.9 14.2 21.2 18.3 17.6 7.8 18.9 20.0 20.8 3.4 12.1 9.8 10.1 15.8 15.8 17.1 23.7 7.7 29.6 18.8 20.8 13.1 18.6 41.1 12.5 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054268-10428891 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.4" "Cell line enhanced" "Detected in many" "HMC-1: 15.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 78.4" "Cell type enhanced" "Detected in many" "eosinophil: 9.0" "Group enriched" "Detected in many" 4 "dendritic cells: 2.3;granulocytes: 9.0;monocytes: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023804, HPA053069" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Intracellular and membrane" 25000 Nucleoplasm "Nuclear bodies, Cytosol" "HPA023804: AB_1853826, HPA053069: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 7.0 8.1 8.0 5.2 7.5 36.1 5.9 78.4 13.7 3.6 5.9 4.3 2.2 5.9 4.8 3.7 5.5 4.2 4.4 8.5 8.9 5.5 32.4 22.9 5.7 6.8 6.8 9.5 4.2 10.2 2.9 3.4 4.6 8.1 3.4 4.0 3.9 6.0 5.0 4.7 3.8 12.7 4.9 6.7 7.2 4.9 8.5 5.5 3.5 4.4 2.6 3.8 3.9 2.7 1.1 2.3 9.0 3.2 1.1 0.8 0.3 0.1 1.1 1.8 5.4 1.6 1.8 0.6 3.3 0.7 0.5 2.2 0.7 2.7 0.0 0.8 3.0 2.9 0.5 0.2 1.7 0.4 0.0 0.5 1.7 2.5 5.3 1.0 15.2 0.5 3.9 0.4 0.0 0.9 0.5 0.3 5.9 0.2 0.0 0.3 0.8 1.0 1.8 1.7 2.3 1.3 1.3 3.1 2.0 5.4 0.2 0.7 2.8 3.3 3.2 2.2 2.6 0.5 1.6 0.2 0.1 0.9 5.9 1.0 4.1 0.8 3.2 9.0 0.7 2.2 0.6 1.1 0.8 0.5 2.3 0.4 0.6 0.5 3.8 1.1 1.6 0.3 0.5 0.3 8.0 7.5 78.4 13.7 8.9 5.5 6.8 9.5 8.1 5.5 MSRB1 "SelR, SelX, SepR, SEPX1" ENSG00000198736 "Methionine sulfoxide reductase B1" Q9NZV6 16 1938210-1943326 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "blood: 195.6;liver: 94.8;pancreas: 107.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 85.8;neutrophil: 195.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 195.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008650, HPA043463, HPA069557" Approved Enhanced Nucleoplasm Nucleoplasm "CAB008650: AB_1619225, HPA043463: , HPA069557: " "unprognostic (3.93e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (9.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.15e-1)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.88e-2)" "unprognostic (4.90e-2)" "unprognostic (5.29e-2)" "unprognostic (3.60e-1)" "unprognostic (4.27e-2)" "unprognostic (8.46e-2)" "unprognostic (4.92e-2)" "unprognostic (7.31e-2)" "unprognostic (4.59e-3)" 7.9 4.0 5.2 9.0 6.3 27.3 5.1 3.2 6.1 5.2 13.1 5.6 7.5 8.7 7.9 13.5 16.9 9.6 13.5 13.7 4.7 4.1 24.9 94.8 9.6 15.6 5.5 4.1 7.3 107.2 2.9 3.9 11.6 4.1 11.0 5.1 6.2 4.7 9.4 20.5 8.0 17.0 14.3 4.3 18.2 9.6 8.1 3.6 3.7 5.5 19.8 4.5 14.8 4.8 1.7 10.9 195.6 26.2 2.4 2.8 12.2 6.6 17.0 6.3 14.9 11.8 5.2 10.8 8.3 10.4 12.1 10.5 27.2 7.4 6.5 27.1 9.5 11.0 10.5 7.2 3.8 36.3 11.9 5.0 6.3 43.4 10.8 14.1 11.9 9.6 6.4 8.7 1.7 12.1 7.8 3.6 6.4 36.8 7.9 23.2 8.6 9.7 11.6 8.7 30.5 18.9 11.2 6.1 8.1 9.3 10.4 5.0 11.3 25.1 7.2 3.7 10.2 7.2 4.8 9.6 15.2 12.4 3.8 13.4 6.4 26.0 26.2 85.8 2.2 12.0 2.1 1.7 1.8 1.8 10.9 1.7 1.4 1.6 195.6 2.4 10.7 4.6 2.8 12.2 5.2 6.3 3.2 6.1 4.7 4.1 5.5 4.1 4.1 3.6 MSRB2 "CBS-1, CBS1, CGI-131, MSRB, PILB" ENSG00000148450 "Methionine sulfoxide reductase B2" Q9Y3D2 10 23095506-23122013 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 72.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027933 Enhanced "Intracellular and membrane" "HPA027933: AB_10601867" "unprognostic (4.89e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-3)" "unprognostic (3.47e-3)" "unprognostic (4.51e-1)" "unprognostic (9.26e-3)" "unprognostic (1.62e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (6.07e-3)" "unprognostic (3.47e-2)" "unprognostic (1.08e-2)" "unprognostic (2.03e-1)" "unprognostic (1.82e-2)" "unprognostic (6.74e-2)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" 13.2 11.6 16.4 6.8 16.2 6.0 9.9 6.5 11.4 10.7 14.4 8.0 14.3 8.2 10.6 15.2 14.1 10.5 15.8 72.3 13.9 14.5 16.0 25.7 7.9 6.3 14.2 8.2 11.3 7.0 11.5 9.4 12.4 9.3 16.3 10.2 10.6 7.7 18.0 31.5 3.6 13.5 25.1 10.8 8.2 7.5 5.6 6.1 6.0 16.7 11.0 5.5 19.0 10.3 0.4 3.1 6.7 2.6 0.3 1.3 0.5 4.1 6.1 11.4 6.9 11.8 10.7 3.4 6.7 3.8 4.3 5.0 4.1 9.2 3.4 6.0 14.3 2.7 3.7 5.0 3.6 23.0 4.2 2.5 10.2 2.3 16.7 0.5 3.0 13.6 8.5 5.1 1.2 6.1 3.3 6.1 9.5 12.6 3.9 3.1 6.3 3.6 4.6 6.5 0.9 5.4 1.6 2.3 15.7 8.3 7.4 13.5 5.0 9.8 4.5 3.8 3.5 8.4 4.0 8.0 2.5 0.1 5.3 7.4 3.1 1.6 2.6 4.1 0.7 2.1 0.6 0.4 0.7 0.5 1.6 0.1 1.3 0.9 6.7 0.3 1.5 3.1 0.7 0.5 16.4 16.2 6.5 11.4 13.9 14.5 14.2 8.2 9.3 6.1 MSRB3 "DFNB74, DKFZp686C1178, FLJ36866" ENSG00000174099 "Methionine sulfoxide reductase B3" Q8IXL7 12 65278643-65491430 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 75.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 37.7;U-937: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 23.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA014432 Uncertain "Intracellular and membrane" "HPA014432: AB_1854146" "unprognostic (1.40e-2)" "prognostic unfavourable (3.84e-4)" "unprognostic (2.86e-3)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-2)" "unprognostic (5.33e-2)" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "prognostic unfavourable (8.85e-8)" "unprognostic (3.29e-3)" "unprognostic (7.80e-2)" "unprognostic (2.08e-2)" "prognostic unfavourable (2.17e-4)" 15.2 3.8 4.5 11.6 5.3 6.4 26.8 5.1 5.2 19.0 39.4 3.6 20.4 4.0 40.3 15.0 23.0 16.1 23.4 30.9 4.8 4.3 4.1 1.4 11.7 4.4 5.0 5.0 13.3 2.5 0.8 3.1 8.7 4.7 19.8 10.2 11.8 4.7 38.4 32.2 3.8 10.0 75.9 5.0 6.5 17.2 6.1 4.8 0.4 6.0 11.2 2.5 33.9 20.9 0.2 6.5 23.4 0.6 4.4 0.1 0.8 2.6 5.7 5.0 23.2 22.5 19.9 0.1 26.2 28.2 10.2 6.1 0.2 0.3 0.0 5.6 37.7 0.5 2.3 6.6 9.3 0.0 4.8 0.0 5.1 0.2 14.7 13.7 0.1 10.5 3.7 8.6 12.1 20.7 0.1 0.1 23.4 0.8 0.0 3.2 1.6 3.1 0.0 6.8 0.1 2.3 0.3 0.1 2.4 9.0 0.5 6.4 4.2 13.2 23.7 13.1 7.1 5.9 10.1 2.4 1.9 0.0 3.6 31.8 8.1 6.3 0.3 23.4 0.1 0.6 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.1 4.0 4.4 0.2 6.5 0.0 0.8 4.5 5.3 5.1 5.2 4.8 4.3 5.0 5.0 4.7 4.8 MST1R "CD136, CDw136, PTK8, RON" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 27.7;intestine: 34.3;skin 1: 28.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.3;HaCaT: 19.5;HBEC3-KT: 21.2;hTCEpi: 29.8;RT4: 22.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "MAIT T-cell: 2.1" "Lineage enhanced" "Detected in single" "T-cells: 2.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favourable (2.33e-5)" 1.7 0.1 0.4 7.5 0.6 0.0 2.4 0.5 0.7 1.8 20.5 0.7 2.0 11.2 1.2 1.3 6.1 0.6 27.7 0.9 0.5 0.1 1.4 0.4 5.0 1.1 0.4 0.6 0.5 4.1 0.0 1.3 0.8 0.9 1.7 9.7 2.5 2.1 0.4 0.5 28.7 34.3 0.7 0.4 0.6 19.1 1.9 0.4 7.7 1.3 6.0 4.5 4.3 3.5 0.2 0.0 0.0 0.0 0.6 2.1 0.0 12.7 4.9 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.2 35.3 0.5 3.1 0.2 19.5 0.0 21.2 0.0 0.3 0.3 0.0 8.4 0.3 0.3 0.0 0.4 0.1 29.8 0.1 4.2 0.0 0.2 0.1 0.0 1.7 0.0 0.0 0.1 10.3 0.8 0.0 0.3 13.0 22.8 0.3 0.0 3.6 8.2 0.0 6.5 0.3 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.4 0.6 0.5 0.7 0.5 0.1 0.4 0.6 0.9 0.4 MT-CO1 "COI, COX1, MTCO1" ENSG00000198804 "Mitochondrially encoded cytochrome c oxidase I" P00395 MT 5904-7445 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Deafness, Disease mutation, Leber hereditary optic neuropathy, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 396.5;heart muscle: 345.0;skeletal muscle: 380.7" "Cell line enhanced" "Detected in all" "HeLa: 859.1" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016241, HPA069328" Enhanced Supported Mitochondria Mitochondria "CAB016241: AB_2229888, HPA069328: " "unprognostic (4.39e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.21e-1)" "unprognostic (1.59e-1)" "unprognostic (3.31e-1)" "prognostic favourable (2.29e-4)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (1.20e-2)" "unprognostic (6.60e-2)" "unprognostic (2.83e-2)" "unprognostic (5.06e-3)" "unprognostic (4.50e-2)" "unprognostic (2.15e-2)" "unprognostic (2.44e-2)" 57.6 82.5 184.1 22.2 164.2 26.4 37.4 40.6 117.1 31.5 80.8 78.1 25.7 42.7 43.5 24.8 32.4 345.0 161.8 111.7 151.0 150.5 20.9 22.6 126.3 23.7 42.5 62.3 10.1 29.0 35.8 84.4 65.6 54.2 380.7 68.9 60.0 38.2 61.2 28.1 65.5 27.8 23.8 21.9 31.6 15.3 292.2 232.9 177.4 396.5 182.8 192.4 130.5 112.7 170.5 232.0 252.3 531.8 243.6 246.0 257.3 85.7 65.0 108.8 205.2 367.8 298.0 123.7 195.5 428.5 26.5 228.0 93.1 140.8 162.5 178.9 859.1 383.8 73.7 103.2 226.6 284.1 237.4 64.2 142.7 78.2 113.5 213.9 192.4 273.1 84.4 462.1 58.9 139.6 110.6 69.3 178.8 329.5 298.3 110.9 147.9 89.2 345.8 160.5 198.4 347.4 311.5 260.6 177.4 255.7 129.0 101.3 97.0 67.6 128.7 272.4 126.6 177.4 396.5 169.3 156.6 236.0 176.4 255.6 154.9 171.8 163.0 292.2 159.7 192.4 93.5 182.8 260.1 232.9 138.6 130.5 MT-ND1 "MTND1, NAD1, ND1" ENSG00000198888 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1" P03886 MT 3307-4262 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Alzheimer disease, Amyloidosis, Diabetes mellitus, Disease mutation, Epilepsy, Leber hereditary optic neuropathy, MELAS syndrome, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 314.4;skeletal muscle: 398.2" "Cell line enhanced" "Detected in all" "HeLa: 660.0" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in all" "basophil: 314.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 314.4" "Low region specificity" "Detected in all" CAB033779 Approved "CAB033779: AB_2149736" "prognostic favourable (3.63e-4)" "unprognostic (3.55e-1)" "unprognostic (3.77e-2)" "unprognostic (3.65e-1)" "unprognostic (3.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.95e-3)" "unprognostic (5.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.05e-2)" "prognostic favourable (3.26e-4)" "unprognostic (8.67e-2)" "unprognostic (8.66e-2)" "unprognostic (3.24e-2)" "unprognostic (1.42e-2)" "unprognostic (3.99e-2)" "unprognostic (2.85e-2)" 83.5 48.0 118.0 15.2 136.1 17.7 31.8 45.0 85.9 19.6 58.3 40.2 16.3 43.4 30.7 16.7 17.6 223.1 106.1 74.3 96.0 104.7 20.5 12.1 101.8 14.2 48.2 35.1 14.3 32.2 26.6 58.6 71.2 48.4 398.2 75.4 33.3 24.6 55.2 16.7 45.0 29.8 13.8 17.1 19.9 9.4 60.8 32.2 314.4 54.4 35.8 46.4 19.5 99.9 102.3 83.9 76.4 318.6 58.0 107.9 86.3 25.5 24.0 25.3 177.8 109.1 122.7 54.9 65.0 66.8 9.2 51.9 48.1 87.5 72.1 136.6 660.0 251.9 68.4 64.6 135.0 137.5 142.0 37.1 53.5 25.7 62.8 76.7 71.0 137.5 52.0 267.8 22.5 77.1 54.8 38.1 65.9 132.8 162.3 34.9 55.6 47.8 76.6 83.7 68.3 224.3 135.2 80.2 72.5 102.2 71.6 85.2 52.5 56.8 53.9 114.6 21.9 314.4 54.4 103.0 25.7 31.4 37.3 54.3 30.8 34.0 20.6 60.8 41.1 46.4 157.8 35.8 32.0 32.2 22.0 19.5 MT-ND3 "MTND3, NAD3, ND3" ENSG00000198840 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3" P03897 MT 10059-10404 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease mutation, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 357.8" "Cell line enhanced" "Detected in all" "ASC diff: 639.2" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063296 Enhanced Approved Cytosol Cytosol "HPA063296: " "unprognostic (1.71e-2)" "unprognostic (1.05e-1)" "unprognostic (8.10e-2)" "unprognostic (3.07e-1)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "prognostic favourable (4.63e-5)" "unprognostic (2.45e-2)" "unprognostic (7.13e-2)" "unprognostic (8.85e-2)" "unprognostic (1.76e-3)" "unprognostic (1.74e-1)" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (1.19e-1)" "unprognostic (2.07e-1)" "unprognostic (5.65e-3)" 102.1 73.9 117.3 17.6 137.2 17.9 59.3 33.7 70.5 31.2 76.3 64.0 25.9 49.2 21.7 24.7 19.7 256.8 110.3 81.7 138.1 145.8 19.7 17.4 92.0 27.5 77.8 14.6 22.2 34.6 39.1 59.1 67.6 50.7 357.8 42.2 48.9 28.4 66.8 19.1 60.6 21.0 25.0 20.3 24.2 15.9 84.8 32.6 159.6 48.5 48.6 75.3 24.4 84.7 138.5 92.5 90.7 639.2 128.1 77.0 71.4 42.0 38.8 43.9 208.4 132.2 88.4 111.0 91.8 176.8 39.7 156.2 66.7 126.6 190.5 86.9 461.1 343.0 99.8 127.8 131.5 221.5 289.5 64.9 73.3 60.3 68.4 103.3 73.1 277.1 67.1 170.7 47.5 128.2 58.2 90.9 81.3 235.9 234.2 38.1 82.9 34.5 69.2 141.3 160.1 206.6 102.3 60.0 91.1 104.2 76.4 40.2 52.6 190.4 48.7 77.7 34.0 159.6 48.5 36.6 36.7 36.4 49.8 73.1 42.6 44.8 32.6 84.8 63.1 75.3 100.7 48.6 32.7 32.3 27.6 24.4 MT-ND4 "LHON, MTND4, NAD4, ND4" ENSG00000198886 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4" P03905 MT 10760-12137 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease mutation, Dystonia, Leber hereditary optic neuropathy, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 392.9" "Cell line enhanced" "Detected in all" "HeLa: 810.9" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053928 Approved "HPA053928: " "unprognostic (8.39e-2)" "unprognostic (1.83e-1)" "unprognostic (7.29e-2)" "unprognostic (9.54e-2)" "unprognostic (5.41e-2)" "unprognostic (3.78e-2)" "unprognostic (2.50e-3)" "unprognostic (8.16e-2)" "unprognostic (1.45e-1)" "prognostic favourable (1.76e-4)" "unprognostic (1.01e-2)" "unprognostic (7.23e-2)" "unprognostic (2.79e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (3.14e-2)" "unprognostic (4.24e-2)" 82.5 72.4 124.2 19.8 138.2 14.9 34.5 43.8 78.5 34.1 68.7 56.5 27.8 37.1 32.9 25.2 23.7 292.7 122.4 90.3 129.8 178.5 20.8 17.4 101.6 25.5 58.3 37.8 19.7 39.1 37.3 82.1 61.7 65.6 288.4 61.1 41.0 37.8 63.6 21.7 67.7 29.6 24.3 23.4 26.0 15.3 164.7 87.6 392.9 119.5 87.1 129.7 53.0 101.4 105.5 137.2 202.5 322.5 81.3 96.1 103.3 39.6 24.0 46.9 160.1 116.2 180.6 91.2 88.0 190.1 12.2 167.3 43.1 104.2 66.4 111.2 810.9 268.4 48.7 111.7 132.3 137.5 177.3 35.3 126.8 58.0 92.6 223.7 86.4 228.8 44.0 253.9 38.8 71.8 59.8 43.1 108.9 175.6 219.4 50.6 68.5 60.1 199.9 103.3 139.9 264.1 160.8 98.3 95.6 131.5 80.0 134.2 54.4 80.4 64.1 194.2 52.2 392.9 119.5 268.8 82.9 91.3 115.5 148.0 93.0 98.9 65.9 164.7 109.6 129.7 105.7 87.1 89.0 87.6 67.6 53.0 MT-ND4L "MTND4L, NAD4L, ND4L" ENSG00000212907 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L" P03901 MT 10470-10766 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease mutation, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 434.4;skeletal muscle: 294.4" "Cell line enhanced" "Detected in all" "HeLa: 879.2" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075648 Approved Mitochondria Mitochondria "HPA075648: " "unprognostic (5.81e-2)" "unprognostic (3.46e-2)" "unprognostic (2.76e-2)" "unprognostic (7.91e-2)" "unprognostic (5.64e-2)" "unprognostic (1.05e-1)" "prognostic favourable (4.47e-4)" "unprognostic (1.97e-1)" "unprognostic (4.04e-2)" "unprognostic (4.63e-3)" "unprognostic (6.61e-2)" "unprognostic (7.38e-3)" "unprognostic (1.39e-1)" "unprognostic (3.09e-1)" "unprognostic (3.73e-1)" "unprognostic (2.97e-2)" "unprognostic (5.68e-2)" 101.1 71.9 102.4 20.3 114.5 13.2 39.4 41.5 73.3 39.4 83.8 48.0 26.1 34.1 30.7 23.9 23.4 187.5 102.7 79.1 123.5 185.7 20.2 13.1 88.6 26.2 43.4 29.7 18.5 30.9 34.2 80.0 43.2 75.4 294.4 31.8 38.4 38.6 59.2 16.1 62.5 27.5 24.6 24.4 25.8 14.3 200.8 111.2 434.4 139.9 112.1 153.0 66.8 96.4 89.7 161.9 164.8 567.3 119.4 71.4 207.0 51.9 32.5 59.4 149.1 89.1 239.3 84.9 139.8 183.9 25.1 221.6 64.7 94.2 103.6 172.0 879.2 276.9 83.3 176.8 154.7 209.0 227.1 61.9 216.8 65.0 94.8 171.6 119.0 172.3 67.2 226.9 40.8 108.4 39.0 69.8 106.4 172.8 203.7 49.1 66.5 101.6 160.9 69.4 114.4 222.6 207.8 85.3 106.2 124.8 79.2 155.3 72.7 127.4 61.2 240.6 39.8 434.4 139.9 290.0 102.4 110.6 140.6 166.9 110.0 117.5 86.1 200.8 132.4 153.0 78.4 112.1 99.4 111.2 79.0 66.8 MTAP "c86fus, MSAP" ENSG00000099810 "Methylthioadenosine phosphorylase" Q13126 9 21802543-21937651 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046915 Approved Cytosol 3100000 Cytosol "HPA046915: " "unprognostic (1.40e-2)" "unprognostic (1.83e-1)" "unprognostic (2.21e-1)" "unprognostic (2.58e-3)" "unprognostic (2.78e-1)" "unprognostic (6.16e-2)" "prognostic unfavourable (4.68e-4)" "unprognostic (9.47e-2)" "unprognostic (2.03e-1)" "unprognostic (8.63e-2)" "unprognostic (4.76e-3)" "unprognostic (4.27e-2)" "unprognostic (6.28e-3)" "unprognostic (2.18e-1)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" 17.0 12.6 7.8 12.6 10.4 8.4 13.9 4.6 10.2 17.3 14.5 12.8 13.4 8.0 21.2 11.6 19.6 12.2 16.9 11.4 7.9 7.7 13.0 17.5 11.4 13.0 12.0 6.2 20.5 17.2 17.6 14.4 17.5 12.3 17.0 13.1 14.3 14.6 15.9 10.8 11.8 10.3 19.9 14.3 17.9 11.7 7.9 10.1 19.1 11.7 14.3 16.2 19.7 17.2 9.3 8.4 1.4 6.9 8.5 8.2 3.5 14.2 2.2 11.6 9.7 9.5 9.8 13.0 20.8 10.2 10.6 12.2 9.8 6.7 7.1 6.5 9.9 6.6 11.8 29.4 18.0 0.1 9.7 0.1 27.0 12.9 9.3 11.4 12.7 11.8 0.0 19.5 21.4 11.0 0.1 9.6 11.1 2.0 13.0 0.3 13.5 17.4 0.1 8.8 12.5 9.1 0.1 6.6 7.5 6.8 8.0 10.3 5.2 0.2 11.9 0.1 7.5 0.1 16.6 6.4 11.3 14.9 0.1 11.3 6.1 1.4 6.9 0.3 5.0 5.4 8.2 7.7 7.2 5.6 8.4 9.3 6.5 5.9 1.0 8.5 3.4 8.0 4.1 3.5 7.8 10.4 4.6 10.2 7.9 7.7 12.0 6.2 12.3 10.1 MTFMT FMT1 ENSG00000103707 "Mitochondrial methionyl-tRNA formyltransferase" Q96DP5 15 65001512-65029639 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Transferase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040710 Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA040710: AB_10794879" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (9.28e-3)" "unprognostic (4.35e-2)" "unprognostic (1.28e-1)" "unprognostic (1.42e-2)" "unprognostic (6.63e-2)" "unprognostic (2.02e-1)" "unprognostic (6.95e-2)" "unprognostic (2.18e-2)" "unprognostic (2.41e-2)" "unprognostic (1.78e-1)" "prognostic favourable (3.31e-8)" "unprognostic (2.75e-2)" "unprognostic (4.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.85e-2)" 8.7 10.2 7.9 10.0 11.5 11.6 7.5 13.5 12.7 9.5 12.7 6.8 8.0 9.7 11.8 10.6 9.5 10.9 9.7 13.8 8.0 7.8 12.8 13.4 8.4 8.6 6.8 9.4 14.0 5.9 7.3 9.3 7.5 10.3 10.8 10.8 12.2 8.7 9.8 13.3 11.6 13.9 12.0 5.7 9.2 8.7 7.2 5.2 9.2 11.7 4.6 8.8 12.0 9.1 5.0 9.6 16.9 3.6 4.6 5.9 1.9 2.6 3.6 3.5 6.1 5.0 3.5 3.1 2.4 4.3 3.2 3.0 2.2 3.0 9.1 3.3 4.4 7.7 6.5 4.3 3.1 3.5 4.8 3.9 3.4 2.5 5.9 5.3 1.2 5.1 5.4 1.7 3.8 2.9 4.1 4.4 4.8 3.6 4.2 5.6 4.8 6.2 3.9 5.1 4.2 5.2 3.1 3.6 3.6 5.8 5.4 4.4 3.3 3.8 5.3 3.8 3.9 4.4 4.8 3.7 5.4 3.6 3.3 8.6 3.9 3.1 3.6 2.4 4.9 2.9 4.9 4.7 4.9 5.2 5.6 5.0 5.5 5.9 16.9 4.6 2.0 9.6 4.9 1.9 7.9 11.5 13.5 12.7 8.0 7.8 6.8 9.4 10.3 5.2 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" P11586 14 64388031-64463457 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis" "Hydrolase, Ligase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 121.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol 250000 Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: " "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavourable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favourable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 18.9 9.0 8.1 8.4 18.1 9.7 12.2 5.7 15.9 7.1 9.3 9.0 4.0 7.5 8.5 6.9 12.0 6.7 6.4 10.6 8.4 6.5 20.5 121.6 6.8 9.2 8.0 10.4 10.1 13.4 13.1 5.6 5.6 10.0 5.5 11.4 9.3 11.6 5.6 26.5 7.6 7.3 8.8 6.9 8.3 7.9 2.3 7.4 15.6 8.6 14.0 12.5 8.7 7.3 21.1 12.8 0.5 13.2 12.8 14.9 8.4 72.1 41.1 15.6 34.0 16.8 13.7 25.3 28.3 19.5 36.8 36.5 39.9 33.3 30.4 13.4 16.8 35.5 48.2 28.2 43.1 30.1 31.7 37.6 41.2 30.2 12.4 28.8 20.5 10.7 9.1 32.8 17.8 22.9 28.0 25.0 27.8 59.9 46.4 16.9 28.6 43.6 37.1 54.3 27.5 27.6 42.3 33.8 13.1 47.4 25.8 14.2 40.1 14.6 14.1 27.8 48.1 25.5 33.9 16.7 20.5 53.5 25.4 33.4 31.4 0.2 8.2 0.1 8.1 13.2 10.9 21.1 9.0 9.9 12.8 11.6 7.6 10.1 0.5 12.8 10.3 3.2 14.9 8.4 8.1 18.1 5.7 15.9 8.4 6.5 8.0 10.4 10.0 7.4 MTHFD1L "DKFZP586G1517, FLJ21145, FTHFSDC1" ENSG00000120254 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like" Q6UB35 6 150865549-151101887 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015006, HPA029040, HPA029041, HPA050052, HPA074911" Approved Supported Mitochondria Mitochondria "HPA015006: AB_1854178, HPA029040: AB_2672879, HPA029041: AB_2672880, HPA050052: , HPA074911: " "unprognostic (3.66e-2)" "prognostic unfavourable (1.68e-5)" "unprognostic (1.02e-1)" "prognostic unfavourable (7.28e-4)" "unprognostic (3.25e-1)" "prognostic unfavourable (5.10e-4)" "prognostic unfavourable (8.33e-5)" "unprognostic (6.35e-3)" "unprognostic (2.45e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "unprognostic (2.93e-2)" "unprognostic (3.51e-1)" "unprognostic (2.91e-1)" "prognostic unfavourable (8.69e-5)" 10.4 10.6 8.0 12.1 8.1 12.2 7.1 32.4 10.5 6.5 6.2 7.8 10.2 3.4 8.5 7.2 6.4 8.0 7.3 10.7 7.5 7.9 9.5 6.9 17.1 11.0 12.3 7.6 22.2 13.7 7.1 9.1 15.5 8.5 5.0 9.1 12.7 3.4 10.5 2.5 5.7 4.7 10.9 10.2 8.7 5.6 13.6 6.6 6.7 12.2 5.0 11.4 8.7 5.1 1.1 3.0 0.2 0.8 1.0 5.0 0.6 11.8 10.3 13.5 33.2 3.5 12.4 33.0 18.7 20.5 18.9 23.2 20.8 11.2 43.8 12.5 28.5 12.7 21.6 18.2 23.4 18.0 19.6 18.3 18.4 19.0 22.3 33.3 3.0 14.6 23.3 18.2 33.3 31.4 43.2 23.0 19.4 25.0 16.3 6.9 13.7 9.6 19.6 10.1 19.5 12.7 5.8 13.5 10.0 24.7 11.0 15.3 3.4 23.3 23.8 12.6 27.7 28.0 26.5 19.1 17.8 45.7 21.0 31.2 16.3 0.2 0.7 0.0 0.8 0.8 1.3 0.8 1.9 2.1 3.0 1.1 1.8 1.9 0.0 1.0 0.8 1.5 5.0 0.6 8.0 8.1 32.4 9.5 7.5 7.9 12.3 7.6 8.5 6.6 MTHFD2 ENSG00000065911 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" P13995 2 74198562-74217565 "Enzymes, Predicted intracellular proteins" "One-carbon metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003684, HPA049657" Approved "Intracellular and membrane" "CAB003684: AB_425867, HPA049657: " "unprognostic (1.82e-3)" "unprognostic (4.60e-2)" "unprognostic (8.12e-2)" "prognostic unfavourable (2.07e-5)" "prognostic favourable (1.01e-4)" "unprognostic (3.10e-3)" "unprognostic (2.24e-3)" "unprognostic (4.75e-3)" "unprognostic (2.64e-2)" "unprognostic (3.96e-2)" "unprognostic (3.76e-3)" "unprognostic (3.57e-3)" "prognostic unfavourable (1.11e-16)" "unprognostic (3.66e-2)" "unprognostic (6.52e-2)" "unprognostic (9.07e-2)" "unprognostic (2.34e-3)" 26.2 5.7 5.8 21.6 14.1 12.1 21.9 3.0 8.0 15.1 12.4 5.9 12.6 10.1 15.8 8.7 14.1 17.5 10.5 12.1 10.0 8.2 12.0 3.4 15.9 21.0 19.0 1.5 20.6 39.7 1.5 15.6 8.2 16.1 12.7 15.3 3.0 32.9 12.0 39.4 8.6 9.2 21.0 25.6 26.3 15.3 11.9 11.8 8.4 11.4 16.7 23.5 20.3 41.8 4.8 11.4 13.6 19.7 10.7 12.7 6.3 18.9 7.0 8.0 27.0 8.8 9.9 21.0 23.9 16.2 14.1 20.0 16.2 8.0 40.1 6.4 13.0 6.7 26.4 14.0 26.6 21.6 11.0 38.7 3.9 15.7 35.8 28.1 25.9 20.4 44.9 17.5 76.1 9.4 17.8 58.4 13.8 11.9 17.6 34.8 17.3 11.7 19.6 22.3 35.3 8.0 5.6 20.7 15.2 8.2 24.9 56.0 21.3 39.1 4.1 4.4 35.3 10.0 26.8 48.4 21.4 32.6 12.2 34.5 12.4 13.6 8.1 9.6 3.3 19.7 4.8 4.8 6.0 3.6 11.4 3.0 4.3 3.3 1.1 10.7 19.1 5.0 12.7 6.3 5.8 14.1 3.0 8.0 10.0 8.2 19.0 1.5 16.1 11.8 MTHFD2L MGC72244 ENSG00000163738 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like" Q9H903 4 74114174-74303099 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035434 Uncertain "HPA035434: AB_10601038" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "unprognostic (2.03e-1)" "unprognostic (2.32e-2)" "unprognostic (1.52e-2)" "unprognostic (4.09e-2)" "unprognostic (2.67e-2)" "unprognostic (7.73e-3)" "unprognostic (1.42e-4)" "unprognostic (3.45e-3)" "unprognostic (4.23e-2)" "unprognostic (5.07e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (1.19e-1)" "unprognostic (3.00e-1)" "unprognostic (1.81e-3)" 5.4 11.7 10.2 6.0 8.8 5.2 10.3 6.9 8.5 4.5 5.6 5.9 8.2 5.3 5.6 10.9 6.3 5.0 5.6 17.7 9.3 10.7 6.9 16.2 7.0 5.8 10.5 4.1 5.8 13.6 6.1 7.4 5.8 6.6 5.3 4.0 4.8 4.9 6.2 9.3 4.2 5.6 4.9 11.0 5.1 4.1 2.9 7.3 14.8 10.5 5.0 3.8 3.8 8.4 3.9 3.9 1.4 6.5 2.5 2.7 2.5 2.6 2.7 3.9 3.5 1.4 2.1 0.9 3.2 2.5 2.2 2.4 2.0 2.5 2.9 4.4 1.4 1.6 3.1 2.1 3.2 2.9 1.9 3.5 1.8 2.5 2.4 5.4 0.7 1.5 5.0 3.2 7.8 4.6 6.0 3.5 2.6 2.5 10.0 7.7 1.1 3.0 10.2 2.6 4.7 13.9 1.3 3.6 7.9 1.8 2.7 3.3 1.5 3.8 4.6 2.5 3.8 4.7 5.3 3.6 4.6 8.3 15.3 1.3 3.7 0.4 2.1 0.9 0.7 2.0 0.7 3.9 0.6 0.9 3.3 1.5 2.1 2.2 1.4 2.5 6.5 3.9 2.7 2.5 10.2 8.8 6.9 7.3 9.3 10.7 10.5 4.1 6.6 7.3 MTHFR ENSG00000177000 "Methylenetetrahydrofolate reductase" P42898 1 11785723-11806920 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Disease mutation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063389, HPA076180, HPA077255" Enhanced Approved "Cell Junctions" "Cell Junctions" "HPA063389: , HPA076180: , HPA077255: " "unprognostic (3.25e-2)" "unprognostic (8.19e-2)" "unprognostic (4.48e-2)" "unprognostic (2.11e-2)" "unprognostic (1.34e-1)" "prognostic favourable (3.97e-5)" "prognostic unfavourable (1.19e-4)" "unprognostic (1.75e-2)" "unprognostic (2.85e-1)" "unprognostic (8.69e-2)" "prognostic favourable (4.81e-5)" "unprognostic (3.10e-1)" "prognostic favourable (2.12e-4)" "unprognostic (2.35e-3)" "unprognostic (2.94e-1)" "unprognostic (4.14e-2)" "unprognostic (1.80e-2)" 11.7 11.0 8.9 10.3 12.4 24.5 9.7 15.3 15.8 9.0 10.4 13.5 8.3 10.7 10.4 54.5 11.3 12.7 10.9 23.4 9.2 8.6 12.0 12.4 16.2 13.3 9.9 10.7 28.8 11.2 6.7 17.5 6.6 10.7 10.2 9.1 14.1 7.3 7.2 15.3 13.2 13.6 10.9 7.4 18.3 13.6 10.6 10.9 10.2 15.8 9.8 11.7 10.4 17.9 4.9 3.2 4.7 7.4 3.4 4.7 2.3 1.3 5.8 6.7 7.7 6.7 10.3 1.1 4.1 8.7 3.9 3.4 5.3 8.5 11.2 2.3 4.2 2.6 4.8 3.9 1.7 5.3 4.3 8.2 7.3 1.5 9.0 4.5 10.7 9.0 4.0 3.0 3.2 6.1 26.9 7.4 4.0 1.8 4.9 2.1 2.2 2.1 5.1 3.7 12.4 6.3 7.0 6.6 11.4 5.1 5.0 8.0 7.9 7.1 5.4 3.9 3.3 4.6 1.0 4.1 5.6 20.9 4.8 10.4 3.6 1.1 3.8 1.9 4.7 7.4 1.8 3.0 1.6 2.5 3.2 4.9 2.4 2.7 4.7 3.4 6.9 1.5 1.0 2.3 8.9 12.4 15.3 15.8 9.2 8.6 9.9 10.7 10.7 10.9 MTHFS HsT19268 ENSG00000136371 "Methenyltetrahydrofolate synthetase" P49914 15 79833585-79897379 "Enzymes, Predicted intracellular proteins" Ligase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 88.7;liver: 120.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 88.7" "Group enriched" "Detected in all" 5 "granulocytes: 88.7;monocytes: 25.4" "HPA008067, HPA054177" Approved Supported Cytosol Cytosol "HPA008067: AB_1078882, HPA054177: " "unprognostic (4.57e-2)" "unprognostic (9.76e-2)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "prognostic unfavourable (8.52e-4)" "unprognostic (9.13e-3)" "prognostic favourable (1.29e-6)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "unprognostic (6.18e-3)" "unprognostic (2.91e-2)" "unprognostic (2.76e-1)" "prognostic favourable (2.04e-4)" "unprognostic (1.36e-1)" "unprognostic (2.85e-1)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" 10.0 6.6 4.5 7.6 4.4 2.5 5.7 3.9 2.8 4.4 12.4 3.7 6.8 8.3 4.3 6.2 4.5 4.0 7.9 5.2 4.1 5.0 27.9 120.9 6.4 5.4 5.5 1.7 3.3 18.8 11.4 9.4 13.9 3.9 8.6 3.7 6.5 10.6 7.6 6.0 1.9 18.3 4.4 6.1 7.6 6.3 5.9 3.3 5.3 12.0 3.1 5.7 4.0 9.9 9.7 9.3 88.7 25.4 12.4 12.6 13.8 11.0 27.9 2.5 1.4 9.9 8.3 11.2 7.7 10.2 13.6 10.4 21.7 21.7 13.8 23.5 9.6 17.8 23.8 7.6 10.4 14.4 15.8 11.9 16.2 25.7 17.1 5.6 0.4 12.6 22.3 5.6 14.2 5.1 26.3 11.4 10.7 23.7 8.6 23.1 11.9 10.5 9.4 13.7 21.0 24.8 20.7 6.8 3.3 21.5 12.9 28.4 16.5 10.3 3.3 5.2 11.1 2.4 5.1 5.7 18.5 14.0 2.6 22.0 4.0 9.8 16.6 43.5 7.7 19.0 9.9 9.7 10.8 9.0 9.3 8.7 12.6 9.7 88.7 12.4 25.4 7.0 11.2 13.8 4.5 4.4 3.9 2.8 4.1 5.0 5.5 1.7 3.9 3.3 MTM1 ENSG00000171100 "Myotubularin 1" Q13496 X 150568619-150673322 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010008, HPA010665" Approved Supported "Plasma membrane" "Plasma membrane" "HPA010008: AB_1079426, HPA010665: AB_1079425" "unprognostic (3.66e-3)" "unprognostic (8.43e-3)" "unprognostic (3.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (6.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.74e-1)" "unprognostic (2.35e-2)" "unprognostic (1.08e-1)" "unprognostic (4.59e-2)" "prognostic favourable (7.40e-7)" "unprognostic (4.46e-2)" "unprognostic (1.25e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" 10.7 17.9 15.0 10.2 16.4 11.1 9.2 10.6 10.8 9.1 21.5 12.5 12.7 12.8 10.9 10.9 11.1 11.1 8.0 9.0 14.3 12.0 17.9 19.9 12.2 12.4 17.3 9.3 13.8 7.5 21.4 11.9 21.5 12.9 9.5 21.6 8.3 10.2 12.9 11.2 10.2 21.0 8.0 17.2 15.3 8.6 12.1 16.4 14.5 12.7 8.3 13.9 8.5 9.1 6.9 7.9 18.4 7.2 10.1 7.7 4.6 8.5 3.9 5.5 2.0 5.0 5.0 3.5 4.1 5.6 4.7 5.2 3.0 4.7 13.8 7.3 5.2 6.1 4.0 7.9 5.8 3.7 3.5 3.7 3.7 9.1 3.8 15.3 12.5 3.0 9.5 3.8 8.1 6.1 2.3 12.8 5.7 2.8 4.2 15.8 2.8 5.1 5.1 3.1 2.7 8.1 4.8 1.4 1.5 3.5 7.4 5.2 2.6 22.3 5.3 3.1 1.9 8.1 4.2 2.6 5.9 13.1 4.0 9.4 5.1 17.6 6.3 18.4 1.5 7.2 4.9 5.5 6.8 5.2 7.9 6.9 6.5 3.9 8.5 10.1 6.2 5.1 7.7 4.6 15.0 16.4 10.6 10.8 14.3 12.0 17.3 9.3 12.9 16.4 MTMR1 ENSG00000063601 "Myotubularin related protein 1" Q13613 X 150692971-150765103 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002977, HPA018502" Approved Approved Centrosome Centrosome "HPA002977: , HPA018502: AB_1854185" "unprognostic (2.37e-2)" "unprognostic (1.64e-3)" "unprognostic (2.07e-1)" "unprognostic (1.05e-2)" "unprognostic (4.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (4.35e-2)" "unprognostic (3.16e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-2)" "unprognostic (1.67e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.19e-1)" "unprognostic (8.40e-2)" 6.9 6.8 20.4 14.0 17.9 9.9 11.8 14.5 15.6 8.3 8.6 8.7 7.2 8.3 9.4 9.2 19.7 9.3 9.0 12.0 17.8 13.4 8.1 10.2 9.7 18.7 12.1 11.5 7.4 11.7 16.3 10.2 37.9 8.8 10.8 9.1 7.9 12.1 13.0 22.2 19.8 10.9 8.3 8.2 18.0 9.7 11.0 9.3 32.6 9.6 10.7 23.1 10.4 7.7 3.3 7.8 7.4 1.5 6.2 4.8 1.8 12.9 8.3 9.0 7.3 2.1 2.4 12.1 11.5 14.9 11.8 16.7 8.0 10.3 28.4 17.1 9.3 11.8 18.1 16.8 18.4 11.5 10.9 1.8 13.0 3.4 6.2 8.3 6.2 6.7 11.7 12.9 0.2 7.1 5.4 7.3 8.4 11.1 12.1 2.1 4.1 12.6 6.5 14.3 12.5 9.2 14.9 13.4 8.4 4.4 9.9 3.7 12.6 4.7 8.9 7.8 6.2 1.0 17.1 9.4 9.6 43.2 1.5 5.4 5.9 0.0 0.9 7.4 3.5 1.5 2.6 2.7 3.9 3.2 2.2 3.3 3.5 4.7 2.4 6.2 1.3 7.8 4.8 1.8 20.4 17.9 14.5 15.6 17.8 13.4 12.1 11.5 8.8 9.3 MTMR2 "CMT4B, KIAA1073" ENSG00000087053 "Myotubularin related protein 2" Q13614 11 95832882-95925315 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049831 Approved Supported Vesicles Vesicles "HPA049831: " "unprognostic (1.71e-2)" "unprognostic (2.55e-3)" "unprognostic (7.81e-3)" "unprognostic (4.16e-1)" "unprognostic (4.18e-3)" "unprognostic (5.36e-2)" "prognostic unfavourable (1.61e-8)" "unprognostic (3.23e-3)" "unprognostic (3.42e-2)" "unprognostic (1.77e-2)" "prognostic unfavourable (3.60e-4)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (8.03e-3)" 16.4 10.4 14.2 12.1 19.9 5.3 15.4 14.9 23.3 14.1 13.5 22.6 4.9 8.0 14.1 7.5 15.5 13.3 15.4 13.8 18.1 13.9 16.9 4.5 14.3 13.6 27.5 13.6 14.5 11.0 15.9 8.2 25.1 21.3 17.6 14.5 19.6 18.8 12.3 6.8 9.7 9.5 18.2 30.0 10.5 13.6 29.0 21.8 12.2 11.3 7.7 11.7 13.4 14.3 5.4 6.6 9.7 4.9 11.8 14.2 6.6 9.2 9.9 22.9 16.5 8.0 12.5 19.1 17.3 15.5 17.3 15.6 23.4 18.8 6.6 20.8 18.3 12.9 18.6 18.9 15.5 12.2 9.0 13.9 24.8 13.1 18.4 23.4 11.4 10.4 12.6 22.6 22.7 25.9 17.1 6.4 16.1 6.9 11.6 10.9 18.6 14.1 9.8 13.4 6.3 17.7 49.8 14.6 17.1 17.1 14.5 7.7 11.5 10.0 26.5 20.1 18.5 14.7 15.9 6.0 16.5 6.1 8.5 6.5 20.4 9.7 3.3 1.4 11.4 3.9 12.3 5.4 7.7 14.2 6.6 4.8 4.1 11.0 0.9 11.8 4.9 3.4 6.9 6.6 14.2 19.9 14.9 23.3 18.1 13.9 27.5 13.6 21.3 21.8 MTMR3 "FYVE-DSP1, KIAA0371, ZFYVE10" ENSG00000100330 "Myotubularin related protein 3" Q13615 22 29883155-30030866 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034515, HPA034516, HPA061399" Uncertain Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA034515: AB_10669726, HPA034516: AB_10669727, HPA061399: " "unprognostic (4.39e-3)" "unprognostic (7.84e-2)" "unprognostic (2.46e-2)" "unprognostic (1.76e-2)" "unprognostic (5.61e-2)" "unprognostic (4.51e-3)" "unprognostic (2.25e-2)" "unprognostic (3.20e-2)" "unprognostic (3.42e-1)" "unprognostic (4.39e-1)" "unprognostic (8.33e-4)" "unprognostic (1.28e-1)" "unprognostic (5.35e-4)" "unprognostic (7.96e-2)" "unprognostic (7.64e-2)" "unprognostic (2.49e-1)" "unprognostic (8.38e-2)" 15.8 17.2 15.7 12.6 20.6 66.7 16.0 24.2 18.0 13.7 12.6 18.9 14.8 10.6 18.8 13.5 20.1 16.7 13.0 14.4 13.0 11.7 12.4 9.9 18.3 12.6 14.7 11.4 20.3 15.8 22.1 20.6 20.6 15.8 15.1 12.9 18.1 15.9 14.7 30.7 22.5 13.1 16.0 17.0 20.7 14.1 23.7 14.6 14.0 16.6 11.9 14.9 14.0 19.3 2.6 3.9 16.5 6.6 3.9 4.1 3.5 8.4 6.6 11.4 12.1 11.5 8.4 8.4 7.5 11.4 10.3 11.9 6.1 5.1 6.4 5.0 14.4 10.4 12.0 9.5 10.4 12.7 10.0 11.6 6.6 6.6 10.6 9.8 29.5 8.9 15.8 10.0 18.2 10.2 7.1 11.5 6.3 10.5 6.6 7.2 4.2 4.9 7.8 15.5 6.5 9.7 15.7 12.7 8.7 14.3 13.0 7.7 7.3 9.9 10.9 16.9 11.4 3.4 5.3 10.0 6.7 6.0 7.3 4.9 7.7 6.4 6.6 10.0 3.1 4.6 4.1 2.2 2.5 3.4 3.9 2.6 3.1 2.7 16.5 3.9 4.7 1.5 2.7 3.5 15.7 20.6 24.2 18.0 13.0 11.7 14.7 11.4 15.8 14.6 MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262507 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, HPA071227" Approved Approved Vesicles,Cytosol "Vesicles, Cytosol" "CAB069425: , HPA071227: " "unprognostic (3.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.45e-3)" "unprognostic (5.50e-2)" "unprognostic (2.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.24e-3)" "unprognostic (3.48e-2)" "unprognostic (1.88e-1)" "prognostic favourable (1.49e-5)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" 11.3 13.9 18.7 13.0 22.5 12.3 14.9 25.2 25.2 11.3 14.5 18.2 10.4 11.2 13.8 23.6 13.1 10.5 15.7 14.2 14.5 13.6 15.8 19.4 10.8 14.3 14.0 14.4 10.7 16.6 26.5 16.0 12.5 15.5 15.2 17.1 14.4 14.2 15.2 24.6 16.5 13.6 15.2 10.4 15.4 13.1 38.6 13.1 16.6 13.2 9.9 15.7 11.7 10.2 3.9 4.0 3.0 6.4 2.6 5.6 2.3 15.2 13.8 18.7 14.1 22.6 10.8 9.3 12.9 12.4 17.2 17.0 14.2 14.1 16.9 11.1 15.2 18.2 25.2 19.7 22.3 13.5 18.4 22.5 28.6 17.9 14.2 21.9 16.8 13.8 15.0 24.6 25.0 21.8 25.1 14.6 12.0 17.4 15.1 16.7 14.1 13.1 15.2 22.0 11.3 15.2 13.8 18.9 13.8 27.6 14.9 16.9 12.1 13.0 23.2 15.1 13.7 11.5 17.2 14.4 13.4 33.3 10.9 23.7 15.8 0.7 2.9 3.0 5.2 6.4 4.3 3.9 3.0 2.7 4.0 3.4 3.6 3.1 2.0 2.6 3.3 3.1 5.6 2.3 18.7 22.5 25.2 25.2 14.5 13.6 14.0 14.4 15.5 13.1 MTPAP "FLJ10486, mtPAP, PAPD1, SPAX4" ENSG00000107951 "Mitochondrial poly(A) polymerase" Q9NVV4 10 30309801-30374448 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transcription" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038620, HPA058232" Approved Supported Mitochondria Mitochondria "HPA038620: AB_10673015, HPA058232: " "unprognostic (2.76e-2)" "unprognostic (2.04e-1)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (3.05e-2)" "unprognostic (1.01e-1)" "prognostic unfavourable (4.20e-6)" "unprognostic (1.16e-1)" "unprognostic (2.04e-1)" "unprognostic (4.78e-2)" "unprognostic (1.77e-1)" "unprognostic (3.56e-2)" "unprognostic (9.02e-2)" "unprognostic (6.28e-3)" "unprognostic (3.77e-1)" "unprognostic (1.14e-2)" "unprognostic (4.39e-2)" 10.9 12.7 9.9 10.2 12.4 32.8 11.1 12.4 16.1 9.6 9.9 7.3 6.5 11.0 10.4 7.0 12.6 9.5 7.6 11.5 7.8 7.2 10.6 11.1 9.4 10.5 11.9 13.0 11.4 18.9 9.5 7.2 10.0 11.4 8.0 12.0 8.2 10.7 10.2 22.3 13.1 10.0 14.3 9.0 9.3 9.7 10.6 8.3 6.7 11.0 12.4 10.5 11.7 9.1 15.6 22.9 18.4 24.4 16.9 17.1 8.3 14.2 14.2 9.0 13.1 8.9 8.4 11.7 9.9 3.5 10.1 10.6 15.0 20.0 20.3 7.1 6.5 16.8 17.4 11.5 12.4 10.2 13.6 20.6 13.4 15.1 9.3 13.4 16.2 8.2 10.8 11.3 6.8 11.0 22.2 16.0 7.6 11.9 16.1 11.9 6.1 7.7 16.3 16.0 18.9 9.3 9.5 14.9 12.0 9.0 9.4 13.8 9.0 8.7 10.5 10.7 13.8 14.9 11.0 3.6 8.6 27.8 9.2 24.7 3.7 16.4 18.5 18.4 16.2 24.4 17.1 15.6 15.4 15.6 22.9 13.1 16.7 16.8 3.0 16.9 18.1 12.0 15.5 8.3 9.9 12.4 12.4 16.1 7.8 7.2 11.9 13.0 11.4 8.3 MTR cblG ENSG00000116984 "5-methyltetrahydrofolate-homocysteine methyltransferase" Q99707 1 236795281-236903981 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Methyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044474, HPA054915" Approved Supported Cytosol Cytosol "HPA044474: AB_10966696, HPA054915: " "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (6.96e-2)" "unprognostic (1.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (4.87e-1)" "unprognostic (1.02e-1)" "unprognostic (2.48e-2)" "unprognostic (3.34e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (1.67e-2)" "unprognostic (8.84e-3)" "unprognostic (1.88e-1)" "prognostic unfavourable (5.75e-4)" "unprognostic (8.10e-2)" 14.5 11.4 9.9 13.2 13.5 7.6 13.6 14.8 14.4 16.9 16.4 16.2 16.0 7.5 18.1 27.3 10.4 18.4 16.3 21.9 9.4 9.8 21.2 9.5 11.7 14.3 12.6 12.8 24.7 20.8 27.4 12.4 17.5 13.0 14.0 8.9 17.7 11.1 17.3 27.0 15.4 11.7 23.3 12.1 13.9 14.9 20.1 12.1 20.8 22.4 11.1 13.2 18.4 14.4 3.3 1.6 3.0 2.0 2.3 5.8 2.1 9.9 6.7 8.2 6.8 15.3 14.1 9.7 8.7 7.8 9.6 10.0 6.3 7.6 22.1 8.1 9.8 6.9 10.6 7.8 11.5 10.2 9.1 13.0 8.9 11.6 10.3 20.6 8.1 20.1 4.9 12.7 12.2 12.7 18.7 10.4 8.0 6.9 10.7 6.6 11.0 3.6 11.7 14.6 14.2 6.9 11.5 6.7 18.7 9.8 7.2 8.8 10.2 8.4 16.4 15.9 6.1 12.2 11.2 22.6 7.0 12.9 10.3 13.0 15.6 2.7 1.6 3.0 3.2 2.0 5.8 2.7 4.2 4.5 1.5 3.3 5.0 4.0 0.1 2.3 1.5 1.6 2.9 2.1 9.9 13.5 14.8 14.4 9.4 9.8 12.6 12.8 13.0 12.1 MTREX "Dob1, fSAP118, KIAA0052, Mtr4, SKIV2L2" ENSG00000039123 "Mtr4 exosome RNA helicase" P42285 5 55307760-55425581 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, rRNA processing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037379 Supported Supported Nucleoplasm Nucleoplasm "HPA037379: AB_10601713" "unprognostic (7.71e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-3)" "unprognostic (1.32e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (1.79e-2)" "unprognostic (5.08e-1)" "unprognostic (4.17e-2)" "unprognostic (1.46e-2)" "unprognostic (5.05e-2)" "unprognostic (7.67e-2)" "unprognostic (1.11e-2)" "unprognostic (2.09e-1)" "unprognostic (3.98e-1)" "unprognostic (2.86e-1)" "unprognostic (2.11e-1)" 23.6 23.6 26.1 24.9 24.0 18.7 24.1 40.6 31.2 22.0 19.3 15.2 28.8 27.6 26.2 17.8 23.3 20.0 22.4 24.3 22.0 16.0 21.2 22.7 19.7 24.7 21.1 21.5 25.9 25.8 35.8 45.0 19.0 26.6 25.6 21.7 10.4 21.8 28.7 71.3 23.8 24.3 20.9 37.5 20.9 20.6 22.3 21.5 29.7 29.3 19.2 21.7 24.4 23.4 9.8 10.9 5.8 10.3 5.9 10.4 4.0 14.2 20.0 14.6 15.5 12.3 13.0 19.6 13.1 10.0 14.8 18.8 21.3 18.7 27.6 15.5 11.5 9.8 28.3 17.9 22.2 4.9 23.5 18.9 18.8 16.3 11.4 11.1 12.5 10.2 12.3 15.6 19.0 12.8 22.3 16.0 14.2 12.9 11.9 14.6 13.2 19.4 14.6 16.3 12.1 16.0 20.8 18.0 11.1 14.9 8.4 12.8 20.3 16.1 11.5 3.8 9.6 10.6 21.9 11.8 12.3 23.8 9.7 25.4 14.7 4.9 6.6 5.8 10.4 6.1 10.0 8.8 7.7 9.7 7.9 9.8 8.1 8.3 1.9 5.9 10.3 10.9 7.5 4.0 26.1 24.0 40.6 31.2 22.0 16.0 21.1 21.5 26.6 21.5 MTRR cblE ENSG00000124275 "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" Q9UBK8 5 7851186-7906025 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038113 Supported Approved "Nucleoplasm,Intermediate filaments,Cytosol" Nucleoplasm "Intermediate filaments, Cytosol" "HPA038113: AB_10671520" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (5.32e-2)" "unprognostic (1.17e-2)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "prognostic unfavourable (6.60e-4)" "unprognostic (2.56e-2)" "unprognostic (5.82e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (9.11e-3)" "unprognostic (3.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" 12.2 12.3 11.2 10.5 13.8 5.4 9.7 15.6 14.3 10.8 10.4 24.1 11.5 10.3 17.3 15.9 10.5 11.3 13.3 15.8 14.2 12.9 22.0 23.9 14.9 11.4 18.1 9.6 13.6 13.6 9.4 13.1 11.6 16.6 10.8 11.9 13.6 11.3 7.4 34.6 10.5 11.5 14.2 22.1 9.3 9.2 8.4 12.5 8.1 14.7 9.9 13.5 13.6 8.8 4.6 4.8 4.6 6.8 3.4 11.4 4.2 9.3 8.8 4.7 10.4 17.9 5.8 13.3 14.5 8.6 7.2 8.2 13.2 7.5 15.7 13.9 11.6 6.0 7.2 7.1 13.6 9.9 8.1 7.5 30.5 7.0 10.9 11.4 3.2 9.4 6.5 12.2 9.0 4.7 9.7 11.9 4.2 1.8 7.3 5.8 3.5 9.8 6.0 5.0 6.6 7.8 7.3 7.3 0.9 25.4 18.5 15.9 5.7 8.9 7.2 16.8 10.6 12.9 11.3 17.7 5.8 12.9 12.2 25.2 8.9 4.6 5.1 4.1 5.5 6.8 9.5 4.6 9.2 7.9 4.8 4.1 5.4 5.1 0.1 3.4 5.4 2.7 11.4 4.2 11.2 13.8 15.6 14.3 14.2 12.9 18.1 9.6 16.6 12.5 MUL1 "C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218" ENSG00000090432 "Mitochondrial E3 ubiquitin protein ligase 1" Q969V5 1 20499448-20508161 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026827 Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "HPA026827: AB_10601137" "unprognostic (1.39e-1)" "unprognostic (2.73e-2)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (6.05e-3)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (5.86e-3)" "unprognostic (4.05e-1)" "unprognostic (9.10e-2)" "prognostic favourable (6.15e-14)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-2)" "unprognostic (2.37e-1)" 13.3 15.9 10.3 12.9 12.3 20.6 20.4 9.2 22.2 13.1 15.8 19.0 8.0 11.6 18.2 10.7 17.2 17.0 18.5 26.2 11.7 12.5 20.5 20.1 16.3 12.1 16.8 9.5 17.5 26.8 21.9 13.0 21.6 17.6 13.9 13.3 14.3 15.3 18.1 26.7 17.4 19.5 17.0 11.7 13.6 15.2 14.1 11.6 18.5 15.1 14.6 14.0 16.3 13.6 23.2 26.0 31.9 30.4 25.2 32.1 27.5 16.9 16.4 9.5 19.6 20.6 11.6 10.3 16.9 20.2 21.0 20.3 10.1 28.2 12.8 18.9 23.8 25.9 17.0 24.4 15.3 12.7 13.5 9.8 11.1 14.6 24.3 13.4 16.8 18.9 32.2 21.5 22.4 13.7 12.7 15.6 22.8 8.6 8.0 9.0 9.7 15.7 7.9 11.9 16.5 24.7 9.5 9.7 14.3 15.1 16.2 20.7 11.4 12.9 15.4 20.5 11.8 17.8 15.1 18.3 15.9 13.8 16.1 18.2 19.0 26.3 26.5 31.9 30.9 30.4 32.1 23.2 23.6 31.4 26.0 21.5 27.1 26.3 24.0 25.2 25.4 20.1 32.1 27.5 10.3 12.3 9.2 22.2 11.7 12.5 16.8 9.5 17.6 11.6 MUT ENSG00000146085 "Methylmalonyl-CoA mutase" P22033 6 49430360-49463191 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Isomerase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035971, HPA035972" Enhanced Approved Mitochondria,Cytosol 110000 Cytosol Mitochondria "HPA035971: AB_10696648, HPA035972: AB_2674895" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.17e-2)" "unprognostic (3.72e-2)" "unprognostic (3.18e-3)" "unprognostic (1.20e-1)" "unprognostic (1.16e-2)" "unprognostic (1.16e-2)" "unprognostic (3.62e-2)" "unprognostic (1.89e-2)" "unprognostic (6.57e-2)" "unprognostic (9.89e-2)" "prognostic favourable (8.71e-13)" "unprognostic (5.38e-2)" "unprognostic (3.78e-1)" "unprognostic (6.01e-3)" "unprognostic (1.91e-1)" 10.7 14.3 10.9 5.7 13.4 4.1 9.7 10.0 12.1 8.9 12.7 8.6 9.0 13.6 8.7 8.6 13.2 8.4 7.5 16.6 10.1 10.0 25.5 96.5 7.8 5.7 11.8 9.5 13.1 15.7 15.8 13.5 7.5 12.0 11.2 11.2 8.0 9.3 9.2 13.7 9.0 14.7 11.8 9.7 6.4 10.9 9.1 9.9 8.2 11.2 9.1 5.8 12.8 8.1 9.4 8.9 14.0 15.2 14.2 12.0 6.7 13.2 4.7 14.3 16.6 28.5 27.1 7.9 11.9 15.7 12.6 18.7 5.4 6.9 12.3 9.5 12.7 7.6 15.9 8.4 17.8 10.5 11.5 6.5 10.8 14.2 20.8 8.3 6.3 16.4 12.6 12.8 15.0 12.1 11.9 14.8 14.8 8.3 9.7 8.3 6.1 3.5 8.8 17.9 17.0 14.6 12.8 13.3 9.2 13.1 9.4 19.7 8.2 13.4 8.7 11.8 8.7 15.9 16.0 5.9 6.6 10.6 16.6 9.9 10.2 14.0 7.5 12.5 7.9 9.9 9.9 9.4 9.5 9.9 8.9 8.3 12.0 9.0 4.3 14.2 15.2 6.3 11.9 6.7 10.9 13.4 10.0 12.1 10.1 10.0 11.8 9.5 12.0 9.9 MUTYH MYH ENSG00000132781 "MutY DNA glycosylase" Q9UIF7 1 45329163-45340470 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA008732 Uncertain Supported Nucleoplasm Nucleoplasm "HPA008732: AB_1854219" "unprognostic (6.30e-3)" "unprognostic (7.12e-2)" "unprognostic (6.29e-2)" "unprognostic (8.80e-2)" "unprognostic (3.43e-1)" "unprognostic (5.16e-3)" "prognostic unfavourable (4.76e-8)" "unprognostic (2.80e-2)" "unprognostic (7.12e-3)" "unprognostic (3.05e-2)" "unprognostic (7.80e-2)" "unprognostic (1.14e-1)" "prognostic unfavourable (7.25e-5)" "unprognostic (3.50e-3)" "unprognostic (1.62e-1)" "unprognostic (5.57e-2)" "unprognostic (5.49e-3)" 7.7 8.4 10.3 12.7 14.8 11.1 8.3 31.6 12.4 10.5 10.1 15.1 11.0 11.1 11.5 9.8 8.3 11.0 10.0 6.1 10.9 7.3 9.7 9.0 7.2 14.0 13.6 10.1 12.9 8.4 7.5 12.5 12.5 11.6 9.1 11.0 12.6 9.5 11.7 8.5 11.1 9.8 7.5 12.6 12.8 11.8 4.9 16.6 14.1 11.9 7.4 12.0 9.3 9.2 7.2 6.5 1.9 8.9 6.6 15.4 6.3 4.9 4.4 10.3 7.0 7.4 5.5 17.9 3.5 4.8 7.5 6.2 9.3 7.1 14.1 6.2 2.4 7.8 5.4 6.4 3.5 11.6 4.1 6.9 7.0 6.6 6.8 5.9 5.0 3.6 6.6 10.1 16.9 5.4 10.7 5.5 3.2 8.1 16.2 5.6 25.9 5.4 22.0 7.9 7.6 3.9 9.5 9.3 7.4 7.6 5.9 11.7 4.7 6.8 3.4 6.6 4.1 5.0 5.5 8.4 9.6 8.6 5.7 9.0 5.0 1.5 5.6 1.9 9.8 8.9 15.4 7.2 10.2 9.9 6.5 7.2 11.3 11.0 0.9 6.6 6.8 5.5 10.3 6.3 10.3 14.8 31.6 12.4 10.9 7.3 13.6 10.1 11.6 16.6 MVD MPD ENSG00000167508 "Mevalonate diphosphate decarboxylase" P53602 16 88651935-88663161 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041404, HPA048250" Uncertain Approved "Cell Junctions,Cytosol" 30000 Cytosol "Cell Junctions" "HPA041404: , HPA048250: " "unprognostic (1.67e-1)" "unprognostic (3.05e-1)" "unprognostic (2.42e-1)" "prognostic favourable (2.17e-4)" "unprognostic (1.89e-1)" "unprognostic (9.56e-2)" "unprognostic (9.26e-3)" "unprognostic (8.33e-2)" "unprognostic (6.68e-2)" "unprognostic (5.47e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-2)" "unprognostic (1.19e-3)" "unprognostic (4.12e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (5.00e-2)" 11.9 18.5 15.8 16.9 19.7 7.6 12.5 21.7 27.9 10.8 19.4 17.1 10.8 39.6 8.4 7.3 30.0 7.4 8.7 11.9 17.2 18.2 9.2 25.9 14.6 12.6 14.6 17.3 11.1 19.0 11.0 7.8 7.6 24.5 13.7 5.1 10.8 16.1 8.7 27.8 18.3 20.7 6.6 23.8 11.1 21.2 23.0 14.6 4.3 9.2 18.6 12.2 7.3 13.8 15.0 17.6 2.5 8.9 18.1 18.1 9.4 14.6 9.4 15.7 10.2 5.3 11.8 8.9 7.3 7.6 5.0 4.2 24.8 37.1 7.1 11.7 4.3 21.8 7.0 38.6 1.4 4.4 11.9 5.2 5.2 37.7 10.8 3.3 3.7 9.3 7.4 13.2 4.2 5.3 14.4 3.9 2.7 34.2 11.1 16.8 18.9 9.2 11.7 4.5 18.3 14.6 9.2 15.9 5.3 18.1 4.1 5.3 20.6 14.8 11.3 4.6 9.4 8.2 4.1 10.8 4.8 24.2 5.6 16.2 7.6 2.5 8.2 1.5 18.1 8.6 13.5 10.3 12.1 11.9 9.5 15.0 9.4 11.5 1.1 18.1 8.9 17.6 12.6 9.4 15.8 19.7 21.7 27.9 17.2 18.2 14.6 17.3 24.5 14.6 MVK "LRBP, MK" ENSG00000110921 "Mevalonate kinase" Q03426 12 109573255-109598117 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Cataract, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016961, HPA044110" Approved Supported Vesicles,Cytosol "Vesicles, Cytosol" "HPA016961: AB_1854220, HPA044110: " "unprognostic (3.10e-1)" "unprognostic (2.27e-2)" "unprognostic (1.85e-1)" "unprognostic (4.43e-2)" "unprognostic (3.66e-2)" "unprognostic (2.08e-2)" "unprognostic (4.30e-2)" "unprognostic (8.98e-2)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (8.23e-2)" "unprognostic (1.30e-1)" "unprognostic (6.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (3.88e-1)" "unprognostic (3.28e-1)" 4.7 14.3 6.8 5.9 11.7 6.8 11.2 6.3 13.1 7.1 7.8 16.7 5.1 11.5 4.2 9.5 23.0 5.1 5.3 6.7 7.8 9.0 16.5 33.1 8.7 4.9 12.5 8.3 8.5 9.3 7.0 6.5 5.5 22.5 9.0 6.3 6.4 8.1 5.8 6.3 19.5 6.9 3.7 18.0 3.8 6.1 17.5 10.5 2.8 11.9 8.5 8.8 5.5 9.9 11.5 7.4 3.4 5.9 8.3 12.2 5.4 12.3 10.4 12.7 6.3 4.1 10.1 6.8 4.5 8.4 11.8 12.9 15.0 15.1 8.7 3.5 4.5 15.1 13.5 21.2 5.7 8.5 9.6 4.6 7.1 22.4 12.7 4.9 5.9 11.0 17.9 21.4 5.8 8.0 8.0 8.3 5.3 15.6 5.0 15.7 10.7 16.1 4.6 9.7 17.0 27.2 18.4 11.8 10.2 8.8 25.1 6.2 23.1 8.6 7.0 5.4 7.1 5.2 5.7 7.0 9.2 12.8 6.5 12.7 7.4 0.7 5.9 3.4 12.2 5.8 9.9 8.4 7.4 11.6 7.4 11.5 11.7 8.3 1.7 8.3 3.7 6.2 6.2 5.4 6.8 11.7 6.3 13.1 7.8 9.0 12.5 8.3 22.5 10.5 MYCBP2 "FLJ10106, KIAA0916, PAM" ENSG00000005810 "MYC binding protein 2, E3 ubiquitin protein ligase" O75592 13 77044655-77327050 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058807 Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA058807: " "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (8.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (6.42e-2)" "prognostic favourable (5.01e-5)" "unprognostic (2.63e-1)" "unprognostic (9.84e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" 28.0 13.4 31.0 26.1 28.8 24.1 22.4 31.3 32.7 15.5 10.9 8.1 11.5 8.0 16.2 26.7 18.9 11.7 11.1 13.5 24.1 18.6 12.3 13.2 12.4 29.8 15.3 31.1 22.8 12.6 14.5 17.2 9.6 20.0 17.9 11.5 9.6 12.9 12.4 13.7 57.6 13.6 13.2 14.0 24.1 10.3 14.1 16.2 18.6 11.6 12.6 30.7 13.3 34.0 8.3 4.6 3.3 3.7 4.2 7.3 2.5 7.7 3.9 4.8 5.2 24.0 10.7 2.8 4.9 7.3 4.3 5.5 3.5 4.0 22.1 3.1 9.6 7.1 8.2 9.0 5.8 8.7 8.2 18.7 8.0 7.2 8.2 39.2 6.6 12.0 7.5 3.9 7.9 9.7 3.9 7.0 7.6 4.6 10.7 26.5 2.5 5.0 12.2 4.9 5.3 7.2 7.7 7.5 3.5 5.9 8.6 4.4 3.2 30.1 12.8 4.1 3.4 2.7 4.7 7.6 5.2 15.7 8.3 32.3 4.1 2.0 3.5 3.2 5.8 3.7 5.1 7.9 6.5 5.0 3.2 8.3 7.3 5.8 3.3 4.2 2.5 4.6 7.3 2.5 31.0 28.8 31.3 32.7 24.1 18.6 15.3 31.1 20.0 16.2 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884331 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 191.1" "Cell line enhanced" "Detected in many" "BJ: 36.5;BJ hTERT+: 55.2;fHDF/TERT166: 45.0;HBF TERT88: 29.0;RPTEC TERT1: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "basophil: 3.6;classical monocyte: 1.3;myeloid DC: 2.8;neutrophil: 4.5;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 13 "dendritic cells: 2.8;granulocytes: 4.5;monocytes: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" 3000000 "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: " "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavourable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavourable (4.46e-4)" 14.9 4.9 4.5 19.8 10.9 0.0 14.4 0.8 5.8 77.1 107.3 22.0 93.2 9.4 111.2 48.3 96.0 56.3 40.6 6.6 4.7 3.2 8.3 5.4 13.2 6.5 25.8 2.8 50.2 1.6 0.5 1.1 8.0 16.0 85.1 27.6 6.0 17.6 158.6 1.6 4.8 33.3 191.1 28.8 7.4 38.7 17.4 13.0 0.2 4.1 2.5 3.4 137.1 21.3 0.2 2.8 4.5 1.3 0.0 0.2 17.3 2.5 7.7 2.1 1.3 2.1 0.4 0.9 36.5 55.2 23.6 17.0 1.6 1.4 0.1 8.2 45.0 0.9 0.9 0.3 29.0 0.0 0.1 20.3 0.2 5.0 11.0 0.1 1.9 6.8 0.7 4.6 6.9 1.8 0.2 0.1 17.5 0.3 0.0 0.5 2.2 1.0 2.3 1.2 6.6 59.6 1.4 0.3 1.1 3.7 0.4 0.6 0.2 0.0 6.7 7.2 2.6 1.7 5.9 0.6 0.7 0.0 18.5 0.2 1.8 3.6 1.3 0.3 0.1 0.2 0.0 0.2 0.0 0.0 2.8 0.1 0.2 0.1 4.5 0.0 0.0 2.7 0.1 17.3 4.5 10.9 0.8 5.8 4.7 3.2 25.8 2.8 16.0 13.0 MYLK2 "KMLC, MLCK2, skMLCK" ENSG00000101306 "Myosin light chain kinase 2" Q9H1R3 20 31819308-31834689 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skeletal muscle: 176.1" "Cell line enhanced" "Detected in some" "Karpas-707: 5.2;RH-30: 13.2;RPMI-8226: 10.7" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059704, HPA059890" Enhanced Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA059704: , HPA059890: " "unprognostic (1.74e-2)" "unprognostic (1.87e-1)" "unprognostic (8.84e-2)" "unprognostic (5.27e-2)" "prognostic favourable (4.00e-4)" "unprognostic (5.58e-2)" "unprognostic (1.38e-7)" "unprognostic (2.29e-1)" "unprognostic (2.60e-3)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (7.25e-11)" "unprognostic (2.01e-1)" "unprognostic (3.15e-1)" "unprognostic (2.60e-2)" "unprognostic (2.70e-2)" 1.4 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 176.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.1 18.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.8 0.0 0.0 0.5 0.1 0.0 0.4 0.1 0.3 0.3 0.6 0.4 0.0 0.1 0.1 0.0 0.2 0.2 0.2 0.7 0.3 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 1.0 0.2 5.2 0.1 0.8 0.7 0.4 0.6 0.4 0.7 13.2 10.7 0.1 0.1 0.7 0.6 3.4 0.1 0.0 0.1 0.1 2.6 0.2 1.0 0.6 2.9 0.1 0.9 0.2 0.2 3.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46703369-46790407 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 62.2;skeletal muscle: 20.8;tongue: 31.1" "Cell line enhanced" "Detected in some" "BEWO: 9.5;HEL: 28.5;K-562: 4.4;SK-BR-3: 6.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons and medulla: 6.6" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.8;hippocampal formation: 5.7" "Region enriched" "Detected in some" 5 "hippocampal formation: 5.2" HPA073447 Enhanced Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA073447: " "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 0.7 0.0 1.7 0.1 0.0 0.1 0.2 0.2 0.0 3.8 0.0 0.0 0.1 3.4 2.0 0.8 0.1 62.2 1.5 1.4 0.4 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.5 0.2 6.6 1.0 0.0 0.0 1.3 0.0 20.8 0.0 0.0 0.0 0.3 0.0 0.0 2.9 0.3 0.0 0.1 31.1 1.1 0.1 0.0 1.2 0.9 2.6 0.7 1.2 0.7 0.2 0.0 0.1 0.1 0.1 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 1.5 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.0 6.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.0 2.5 0.7 0.6 0.6 0.4 0.4 0.7 0.5 0.5 0.3 1.2 0.7 0.7 2.6 1.2 0.5 0.9 0.3 0.2 0.7 1.7 0.1 0.2 1.5 1.4 0.1 0.4 6.6 0.3 MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2750966 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 23.6;tongue: 63.6" "Cell line enriched" "Detected in some" 6 "HEL: 12.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: AB_2147922" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.87e-1)" "unprognostic (5.22e-3)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (7.48e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.19e-2)" "unprognostic (4.63e-2)" 0.5 0.3 0.3 0.3 0.4 0.4 0.8 1.4 0.7 0.3 0.3 0.3 0.3 0.1 0.3 0.5 1.0 0.2 0.3 1.0 0.5 0.5 2.6 0.3 0.5 0.3 0.4 0.3 0.3 1.1 0.7 0.7 0.4 0.4 0.4 0.1 0.4 2.4 0.4 23.6 0.8 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 1.0 63.6 1.5 0.5 0.3 0.1 0.8 0.3 0.3 0.9 1.4 0.1 0.3 0.1 0.6 1.1 1.0 1.2 0.6 0.7 1.5 0.5 0.4 0.5 1.0 1.0 1.6 0.8 1.9 0.2 0.4 0.7 0.2 0.6 12.4 0.6 0.1 0.3 0.3 0.6 1.5 0.5 0.1 1.2 0.5 0.1 0.1 0.3 0.5 0.1 1.3 0.2 0.0 0.9 0.0 0.0 0.8 0.3 1.0 0.6 0.3 0.2 0.5 0.4 0.8 0.7 0.5 0.1 0.2 0.4 0.4 0.2 0.1 0.2 0.3 1.2 0.1 0.1 0.1 0.5 0.0 0.3 0.1 0.2 1.4 0.2 0.1 0.6 0.1 0.3 0.9 0.3 0.8 0.1 0.1 0.3 0.4 1.4 0.7 0.5 0.5 0.4 0.3 0.4 0.3 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934071-26212536 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 8.1;testis: 12.5" "Cell line enhanced" "Detected in some" "AF22: 2.3;CAPAN-2: 2.2;HEK 293: 2.6;SCLC-21H: 2.4;U-2 OS: 4.3;U-698: 10.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 5.0;cerebral cortex: 1.9;hypothalamus: 1.3;pons and medulla: 5.4" "Cell type enriched" "Detected in single" 12 "naive B-cell: 1.1" "Lineage enriched" "Detected in single" 12 "B-cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA048951, HPA051893" Approved Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA048951: , HPA051893: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.8 0.7 0.4 0.3 5.0 0.5 1.5 0.3 1.9 2.1 0.6 0.1 0.7 0.4 0.3 3.2 0.9 1.1 0.3 0.3 0.5 1.3 0.9 0.2 1.0 0.3 0.2 0.0 0.5 2.1 0.2 8.1 0.2 5.4 0.5 1.1 3.8 0.2 0.6 0.3 2.2 0.6 1.0 0.4 0.3 0.9 12.5 0.8 0.0 1.3 1.4 0.9 0.5 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.0 0.0 1.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.0 0.3 1.9 0.5 1.3 0.2 0.0 5.4 0.8 MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.0;parathyroid gland: 12.6;retina: 21.6" "Group enriched" "Detected in some" 10 "HDLM-2: 11.0;HEL: 10.1;RT4: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "gdT-cell: 1.4;naive CD8 T-cell: 1.1" "Lineage enriched" "Detected in single" 5 "T-cells: 1.4" "Region enriched" "Detected in single" 5 "basal ganglia: 4.7" "Not detected" "Not detected" HPA045483 Approved "HPA045483: " "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (7.15e-3)" "unprognostic (5.07e-2)" "unprognostic (2.61e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-1)" "unprognostic (7.99e-3)" "unprognostic (2.59e-1)" "unprognostic (4.25e-5)" "unprognostic (2.34e-1)" "unprognostic (8.12e-3)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" 0.2 0.2 0.3 0.0 0.3 0.0 0.2 0.2 0.3 0.6 0.2 0.0 4.6 0.0 0.3 20.0 0.3 0.5 0.0 0.3 0.3 0.5 8.5 0.2 0.3 0.5 0.3 0.3 0.4 2.2 12.6 1.0 0.0 0.3 0.3 0.0 21.6 1.4 1.1 0.2 0.5 0.2 0.5 0.2 0.3 0.2 4.2 0.0 0.0 2.2 0.0 0.8 4.4 0.3 0.1 0.3 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.2 0.3 0.3 0.5 0.3 0.3 0.3 0.0 MYSM1 KIAA1915 ENSG00000162601 "Myb like, SWIRM and MPN domains 1" Q5VVJ2 1 58654739-58700092 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, DNA-binding, Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054291, HPA067133" Approved Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA054291: , HPA067133: " "unprognostic (2.95e-3)" "unprognostic (3.64e-2)" "unprognostic (3.20e-2)" "unprognostic (8.68e-2)" "unprognostic (2.08e-2)" "prognostic favourable (5.09e-5)" "unprognostic (8.12e-3)" "unprognostic (9.63e-3)" "unprognostic (5.72e-3)" "unprognostic (3.74e-1)" "unprognostic (2.25e-1)" "unprognostic (4.56e-2)" "unprognostic (2.38e-3)" "unprognostic (4.22e-2)" "unprognostic (1.83e-1)" "unprognostic (8.45e-2)" "unprognostic (1.44e-2)" 13.2 12.3 14.1 14.4 15.7 24.4 17.3 16.9 24.3 14.3 13.7 11.4 11.9 12.5 17.5 14.3 13.5 13.0 9.9 14.1 11.7 8.1 11.0 11.0 12.9 14.3 14.0 13.3 18.1 14.0 16.5 19.2 11.3 18.0 14.4 11.6 9.3 15.5 15.2 23.2 20.4 14.6 13.7 15.2 14.2 11.5 8.3 14.7 11.9 15.5 10.6 12.9 13.3 14.7 1.1 0.7 2.2 2.1 0.2 2.3 0.5 8.2 2.4 6.1 6.5 5.6 7.2 8.8 4.9 5.5 4.9 4.3 4.1 3.6 8.6 1.5 3.7 6.3 6.7 2.9 9.5 5.8 4.6 10.3 1.1 4.5 6.8 15.6 7.9 5.2 4.9 6.4 3.3 1.2 11.0 5.5 5.6 2.8 7.7 13.1 9.7 4.5 6.5 14.8 5.3 4.0 3.2 5.1 4.9 4.2 8.2 11.6 2.5 8.9 4.0 8.8 4.0 6.8 9.4 10.1 4.7 11.4 5.1 11.4 9.6 0.8 0.7 0.5 2.0 1.0 1.4 0.9 1.4 1.6 0.6 1.1 2.3 1.1 2.2 0.2 2.1 0.7 1.4 0.5 14.1 15.7 16.9 24.3 11.7 8.1 14.0 13.3 18.0 14.7 NAA10 "ARD1, ARD1A, DXS707, TE2" ENSG00000102030 "N(alpha)-acetyltransferase 10, NatA catalytic subunit" P41227 X 153929242-153935223 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006269, HPA030711" Supported Supported Nucleoli,Cytosol Cytosol Nucleoli "CAB006269: AB_425759, HPA030711: " "unprognostic (7.57e-2)" "unprognostic (1.40e-2)" "unprognostic (1.81e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (1.94e-2)" "unprognostic (4.52e-3)" "unprognostic (1.22e-1)" "unprognostic (1.68e-1)" "unprognostic (1.04e-1)" "unprognostic (9.01e-2)" "unprognostic (9.63e-2)" "prognostic unfavourable (3.29e-8)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (7.48e-3)" 18.9 21.2 17.7 20.3 14.0 12.5 31.8 15.5 20.8 12.4 15.3 8.1 19.2 16.7 17.2 17.6 19.7 16.5 17.6 26.4 15.0 14.2 16.3 18.6 20.7 30.0 15.0 18.0 14.1 33.3 12.3 12.0 13.7 17.5 13.6 11.7 9.3 19.0 17.9 57.8 14.1 14.7 21.7 14.7 14.9 17.7 7.1 11.8 11.4 12.2 25.3 16.3 17.1 22.1 33.7 34.8 35.0 31.9 27.6 44.8 29.0 31.8 33.6 6.3 20.6 9.1 9.5 18.0 11.2 6.6 15.3 13.5 21.8 10.1 24.2 37.4 9.3 15.3 13.3 13.5 6.0 10.1 61.9 8.7 23.5 21.9 12.4 16.9 19.3 7.2 15.2 14.3 14.8 17.3 17.4 10.3 10.1 41.9 27.0 25.3 10.6 46.6 21.5 16.4 26.6 11.2 14.7 13.6 16.4 4.4 17.7 26.5 9.5 14.1 10.0 6.4 22.1 22.3 34.0 21.8 24.3 45.5 8.7 21.9 18.7 12.0 24.2 35.0 29.0 28.0 38.0 33.7 31.2 31.7 31.6 32.6 18.7 28.0 22.6 27.6 31.9 34.8 44.8 29.0 17.7 14.0 15.5 20.8 15.0 14.2 15.0 18.0 17.5 11.8 NAA11 "ARD1B, ARD2, hARD2" ENSG00000156269 "N(alpha)-acetyltransferase 11, NatA catalytic subunit" Q9BSU3 4 79225694-79326050 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 166 "placenta: 32.1;testis: 30.5" "Group enriched" "Detected in some" 6 "K-562: 9.1;U-266/70: 26.0;U-266/84: 8.3" "Cancer enhanced" "Detected in some" "testis cancer: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035922 Approved Supported "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA035922: AB_10673490" "unprognostic (7.37e-2)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (4.67e-1)" 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 32.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 30.5 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 26.0 8.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 NAA20 "dJ1002M8.1, NAT3, NAT5" ENSG00000173418 "N(alpha)-acetyltransferase 20, NatB catalytic subunit" P61599 20 20017116-20033655 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063344 Supported Cytosol Cytosol "HPA063344: " "unprognostic (2.94e-2)" "unprognostic (1.14e-1)" "unprognostic (7.14e-2)" "unprognostic (2.59e-1)" "unprognostic (1.89e-1)" "prognostic unfavourable (1.96e-4)" "unprognostic (2.00e-2)" "unprognostic (1.11e-2)" "unprognostic (2.40e-1)" "unprognostic (6.18e-2)" "unprognostic (9.30e-2)" "unprognostic (3.85e-1)" "unprognostic (2.93e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-1)" "unprognostic (2.28e-1)" "unprognostic (1.32e-1)" 15.9 20.0 14.2 10.0 21.4 17.4 23.2 15.5 34.1 17.3 12.7 12.0 22.7 9.7 20.5 17.7 58.4 15.8 12.3 24.1 14.7 14.1 24.6 25.0 15.7 19.0 13.1 18.3 12.9 43.2 24.8 20.0 18.5 19.4 14.4 12.2 11.2 22.0 20.6 35.2 15.6 11.0 17.3 13.1 11.0 14.5 43.7 10.2 9.5 23.6 37.5 22.1 14.0 23.7 18.6 28.3 20.4 27.5 17.7 25.8 26.4 40.2 24.5 8.8 13.8 18.7 19.7 13.3 29.8 20.4 26.9 25.2 12.5 29.3 21.9 16.2 20.1 32.0 15.1 47.8 21.9 9.8 16.4 16.4 6.5 18.7 26.8 17.3 12.2 22.4 31.5 27.2 27.5 23.0 26.5 22.6 23.4 31.6 24.3 18.0 6.9 40.0 13.4 34.8 29.0 26.4 9.3 16.8 11.4 18.0 50.9 24.9 31.4 27.9 25.0 22.3 13.1 26.8 27.3 24.6 30.7 23.6 13.6 15.2 15.9 8.0 27.5 20.4 17.6 27.5 25.8 18.6 20.5 20.2 28.3 16.5 19.9 22.0 3.6 17.7 23.2 22.9 20.8 26.4 14.2 21.4 15.5 34.1 14.7 14.1 13.1 18.3 19.4 10.2 NAA30 "C14orf35, FLJ35355, MAK3, Mak3p, NAT12" ENSG00000139977 "N(alpha)-acetyltransferase 30, NatC catalytic subunit" Q147X3 14 57390544-57415917 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057824 Uncertain Supported Cytosol Cytosol "HPA057824: " "unprognostic (5.13e-2)" "unprognostic (7.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (6.31e-2)" "unprognostic (1.84e-2)" "unprognostic (5.44e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (5.21e-2)" "prognostic favourable (1.25e-8)" "unprognostic (1.77e-1)" "unprognostic (1.67e-1)" "unprognostic (5.75e-3)" "unprognostic (1.63e-1)" 10.7 10.3 15.8 10.7 18.3 15.0 16.4 18.1 18.9 9.9 15.0 9.2 8.6 11.4 12.1 8.8 13.5 9.1 12.5 18.8 13.9 15.6 14.7 19.1 8.2 9.6 12.9 16.4 18.1 10.5 16.2 13.4 15.4 12.0 12.3 9.6 9.6 10.8 12.8 34.9 10.5 13.5 13.0 9.9 9.8 8.6 21.4 10.1 15.0 12.6 13.6 10.3 12.8 13.7 2.6 1.5 1.7 5.3 5.5 4.2 0.8 13.8 13.3 7.7 12.4 12.9 17.0 12.9 16.3 15.8 12.5 11.4 12.0 10.3 10.2 14.4 13.4 14.7 13.7 10.5 20.8 17.7 7.0 8.2 7.7 10.4 13.5 16.5 9.6 11.5 15.6 11.3 18.9 19.1 8.0 10.2 16.4 16.0 13.7 9.6 8.2 14.9 11.0 22.0 7.9 12.8 12.7 16.5 8.6 13.7 13.6 16.4 17.5 8.6 16.6 19.6 20.5 10.7 10.3 7.5 9.2 12.5 13.0 8.3 13.8 1.7 0.9 0.5 2.9 2.1 3.0 2.3 2.8 4.2 0.8 2.6 3.0 2.8 0.4 5.5 5.3 1.5 3.7 0.8 15.8 18.3 18.1 18.9 13.9 15.6 12.9 16.4 12.0 10.1 NAA40 "FLJ13848, NAT11" ENSG00000110583 "N(alpha)-acetyltransferase 40, NatD catalytic subunit" Q86UY6 11 63938959-63957328 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037816 Uncertain Approved "Nuclear bodies" "Nuclear bodies" "HPA037816: AB_10672289" "unprognostic (3.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-1)" "unprognostic (6.88e-3)" "unprognostic (1.50e-1)" "unprognostic (2.11e-1)" "prognostic unfavourable (1.43e-7)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (1.58e-1)" "unprognostic (7.01e-3)" "unprognostic (6.29e-3)" "unprognostic (3.42e-2)" "unprognostic (6.43e-3)" "unprognostic (2.49e-1)" "unprognostic (1.55e-1)" "unprognostic (5.25e-2)" 4.9 12.4 9.8 10.0 11.6 4.1 7.6 16.7 13.5 7.1 7.3 12.2 10.8 9.2 5.0 7.7 9.2 11.2 7.6 13.8 9.8 10.0 10.0 5.1 6.1 10.7 8.3 8.6 4.2 8.9 28.0 22.7 10.5 8.9 6.0 7.9 12.2 9.7 11.3 7.5 4.5 9.8 5.4 7.6 12.5 6.3 19.2 8.9 10.1 10.1 4.1 11.7 8.1 4.9 4.1 5.0 3.5 0.8 6.7 10.1 2.8 10.5 12.4 15.5 8.3 4.4 4.2 9.8 7.8 8.4 19.5 13.8 10.2 13.5 6.5 9.8 7.0 9.6 12.9 5.7 14.5 8.5 8.0 8.9 7.8 11.5 5.8 14.0 7.7 4.4 5.2 12.1 3.3 12.6 15.0 5.0 9.0 8.0 15.0 11.1 14.3 8.3 14.9 13.9 8.3 13.0 8.2 20.5 10.9 12.3 10.8 6.4 17.6 6.3 8.1 10.9 13.2 6.3 6.4 5.9 3.7 11.5 6.5 6.1 8.4 3.3 0.8 3.5 10.1 0.6 3.6 4.1 2.7 4.8 3.6 3.9 1.7 4.1 0.3 6.7 0.3 5.0 0.8 2.8 9.8 11.6 16.7 13.5 9.8 10.0 8.3 8.6 8.9 8.9 NAA50 "FLJ13194, MAK3, NAT13, NAT5, San" ENSG00000121579 "N(alpha)-acetyltransferase 50, NatE catalytic subunit" Q9GZZ1 3 113716460-113746300 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 86.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074489 Approved "HPA074489: " "unprognostic (9.74e-2)" "unprognostic (1.49e-1)" "unprognostic (3.19e-2)" "prognostic unfavourable (2.32e-4)" "unprognostic (4.75e-2)" "unprognostic (1.51e-1)" "prognostic unfavourable (1.51e-5)" "unprognostic (1.62e-3)" "unprognostic (6.82e-2)" "unprognostic (3.43e-1)" "prognostic unfavourable (7.92e-5)" "unprognostic (2.97e-3)" "unprognostic (1.09e-1)" "unprognostic (2.25e-2)" "unprognostic (9.59e-2)" "unprognostic (7.13e-3)" "unprognostic (2.43e-1)" 23.4 23.6 15.9 18.0 19.8 19.7 25.6 17.1 16.5 14.7 16.2 9.3 12.9 12.7 18.4 13.3 32.6 14.7 13.6 17.0 14.1 10.8 17.6 31.8 17.3 20.7 13.8 13.7 17.8 20.7 18.4 14.1 14.9 15.6 14.5 14.7 10.7 21.6 13.8 86.5 17.7 14.0 16.1 15.7 17.7 16.9 19.0 12.9 22.5 18.3 37.0 23.2 19.9 19.8 32.3 24.7 28.7 22.6 17.4 27.3 26.2 88.9 38.9 21.4 24.9 29.1 23.6 44.7 47.9 27.0 29.6 34.1 55.8 32.1 61.6 29.7 25.4 36.8 37.2 32.8 54.4 12.9 19.0 66.4 29.3 33.5 26.7 69.0 21.6 20.1 25.9 33.1 47.9 26.4 41.7 24.9 30.5 42.1 45.6 15.0 47.9 57.3 47.0 32.8 48.6 22.5 67.9 33.0 19.1 34.7 25.9 34.8 35.9 23.0 24.3 40.9 40.7 17.2 36.0 27.7 45.8 114.3 32.1 38.9 25.1 8.5 22.5 11.9 27.3 22.6 24.3 32.3 20.6 25.5 24.7 20.5 18.2 24.0 28.7 17.4 19.8 14.4 21.9 26.2 15.9 19.8 17.1 16.5 14.1 10.8 13.8 13.7 15.6 12.9 NAA60 "FLJ14154, NAT15" ENSG00000122390 "N(alpha)-acetyltransferase 60, NatF catalytic subunit" Q9H7X0 16 3443611-3486963 "Enzymes, Predicted intracellular proteins" "Chromosome partition" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040916 Approved Uncertain "Actin filaments,Cytosol" "Actin filaments, Cytosol" "HPA040916: AB_10794428" "unprognostic (8.59e-2)" "unprognostic (2.16e-3)" "unprognostic (3.39e-1)" "prognostic favourable (3.14e-4)" "unprognostic (1.81e-1)" "unprognostic (5.90e-2)" "unprognostic (2.88e-2)" "unprognostic (1.53e-2)" "unprognostic (5.23e-2)" "unprognostic (5.12e-2)" "prognostic favourable (4.30e-4)" "unprognostic (9.54e-2)" "unprognostic (1.64e-1)" "unprognostic (1.60e-2)" "unprognostic (8.96e-2)" "unprognostic (3.59e-1)" "unprognostic (6.74e-3)" 18.5 28.7 24.2 17.9 30.8 26.6 16.2 38.1 40.2 17.1 29.4 29.1 34.0 36.8 24.3 18.6 21.3 21.7 23.7 26.2 25.6 21.3 35.8 40.3 23.6 19.4 21.6 17.7 21.2 41.8 46.4 29.0 27.0 24.4 23.7 21.4 29.1 20.7 31.6 38.9 16.9 42.2 19.9 25.7 28.1 34.8 25.3 19.0 22.8 21.8 21.8 24.1 21.7 22.1 8.5 11.2 34.8 13.2 11.6 13.4 10.0 8.1 32.0 22.7 23.8 18.1 12.4 20.3 15.6 16.6 16.1 14.6 21.9 17.6 16.9 15.9 17.7 19.1 22.4 18.2 15.8 25.5 15.1 20.6 20.2 25.6 19.7 26.4 27.3 15.2 14.1 11.1 21.4 25.9 21.7 24.2 11.4 37.3 16.6 19.4 27.7 9.4 20.8 17.2 25.6 16.7 17.2 12.0 26.0 23.2 25.9 12.3 23.0 18.6 19.1 20.8 17.8 6.7 14.4 20.2 18.7 16.5 6.6 16.3 15.8 19.8 10.5 34.8 11.8 12.3 12.5 8.0 10.8 11.5 11.2 8.5 9.3 10.8 13.2 11.6 13.2 7.8 13.4 10.0 24.2 30.8 38.1 40.2 25.6 21.3 21.6 17.7 24.4 19.0 NAALAD2 "GCPIII, NAALADASE2" ENSG00000077616 "N-acetylated alpha-linked acidic dipeptidase 2" Q9Y3Q0 11 90131515-90192894 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 44.1" "Group enriched" "Detected in some" 5 "CACO-2: 19.7;SH-SY5Y: 6.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 12 "monocytes: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060820, HPA065419" Approved Approved Nucleoplasm Nucleoplasm "HPA060820: , HPA065419: " "unprognostic (1.68e-1)" "unprognostic (2.66e-3)" "unprognostic (1.49e-1)" "unprognostic (4.52e-3)" "unprognostic (4.73e-3)" "unprognostic (2.97e-1)" "unprognostic (3.82e-3)" "unprognostic (1.77e-2)" "unprognostic (2.44e-1)" "unprognostic (2.30e-1)" "unprognostic (3.30e-2)" "unprognostic (8.00e-2)" "unprognostic (9.97e-4)" "unprognostic (1.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.63e-2)" "unprognostic (2.93e-1)" 7.7 13.0 5.3 1.8 9.9 1.1 3.1 2.1 9.8 7.8 2.1 3.7 2.8 1.3 10.3 5.4 1.8 4.7 3.7 2.5 5.5 7.4 2.7 1.7 2.8 1.6 6.5 5.0 12.9 2.5 0.9 44.1 8.8 11.9 5.2 2.2 5.8 1.9 3.7 2.1 1.5 2.1 3.5 6.2 4.4 1.8 16.6 7.4 0.0 1.7 1.7 1.2 1.8 3.8 0.0 0.1 0.0 2.4 0.0 0.1 0.1 0.1 0.2 1.9 0.1 0.6 0.1 2.4 0.1 0.1 0.1 0.0 19.7 0.7 0.3 0.2 0.0 0.3 1.4 0.0 0.0 0.0 0.4 1.8 0.4 1.7 0.2 0.1 0.1 2.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.3 0.3 1.9 0.2 0.3 0.0 0.2 0.0 0.0 0.2 6.6 0.0 0.2 0.0 0.2 0.4 2.5 0.1 1.6 0.4 0.3 1.1 0.3 0.3 0.7 0.3 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.1 0.1 5.3 9.9 2.1 9.8 5.5 7.4 6.5 5.0 11.9 7.4 NAALADL1 ENSG00000168060 "N-acetylated alpha-linked acidic dipeptidase like 1" Q9UQQ1 11 65044818-65058549 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "blood: 49.5;intestine: 123.4" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.3;fHDF/TERT166: 6.7;HHSteC: 18.6;HSkMC: 12.2;SCLC-21H: 9.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 49.5" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047123 Enhanced Uncertain Cytosol Cytosol "HPA047123: " "unprognostic (2.98e-2)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "unprognostic (8.76e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-3)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.75e-4)" "unprognostic (2.10e-3)" "unprognostic (3.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.80e-2)" 4.1 0.9 1.4 3.3 1.6 7.0 4.1 1.9 1.4 6.0 54.3 1.2 2.6 7.8 7.2 1.8 2.7 4.4 3.4 3.5 1.3 0.6 2.3 1.2 3.4 5.2 1.5 1.5 6.2 1.0 0.9 2.0 1.5 1.6 4.6 2.6 3.1 2.3 4.8 2.0 1.6 123.4 4.3 1.4 5.0 2.8 1.8 1.2 1.8 1.8 2.3 2.9 3.1 5.4 8.8 4.9 49.5 6.3 22.2 12.9 7.0 0.0 0.0 0.1 0.2 0.4 5.3 0.9 2.0 0.0 2.5 1.1 0.0 0.0 0.1 0.0 6.7 0.0 0.0 0.1 0.0 0.7 0.3 0.0 0.1 3.0 18.6 0.0 0.0 12.2 0.0 2.4 0.0 3.2 0.0 0.2 0.0 0.2 0.2 0.6 0.0 0.1 0.1 0.0 0.8 0.2 0.0 9.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.7 0.0 0.1 0.1 49.5 6.3 10.3 9.5 4.3 4.9 8.0 7.6 4.8 4.9 8.8 8.8 4.9 1.1 22.2 2.5 0.2 12.9 7.0 1.4 1.6 1.9 1.4 1.3 0.6 1.5 1.5 1.6 1.2 NAALADL2 ENSG00000177694 "N-acetylated alpha-linked acidic dipeptidase like 2" Q58DX5 3 174438573-175810552 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 29.3" "Cell line enhanced" "Detected in some" "ASC TERT1: 11.5;BJ hTERT+: 4.1;fHDF/TERT166: 4.8;WM-115: 4.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA012413, HPA017425, CAB025586" Approved Enhanced Nucleoplasm Nucleoplasm "CAB025586: , HPA012413: AB_1854274, HPA017425: AB_1854275" "unprognostic (7.28e-3)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (1.60e-1)" "unprognostic (2.56e-1)" "unprognostic (2.56e-1)" "unprognostic (2.29e-4)" "unprognostic (3.44e-3)" "unprognostic (5.70e-2)" "unprognostic (7.42e-2)" "unprognostic (7.85e-3)" "unprognostic (9.49e-2)" "unprognostic (3.66e-6)" "unprognostic (7.11e-2)" "unprognostic (1.48e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" 4.9 2.3 2.2 4.6 3.7 0.8 7.0 1.9 2.7 8.3 8.3 5.4 23.8 2.4 9.7 10.5 2.3 5.0 8.9 5.4 2.5 1.8 7.0 3.7 3.3 1.3 2.3 2.0 5.4 3.9 20.6 3.0 6.4 4.0 9.6 3.3 4.4 17.0 29.3 1.8 3.2 6.6 6.0 3.6 2.6 4.5 1.9 2.9 4.9 3.5 2.6 1.7 8.7 5.0 0.1 1.7 0.2 0.1 0.1 0.8 0.0 0.0 0.0 0.2 0.0 3.5 11.5 0.1 2.3 4.1 0.5 0.7 0.1 1.2 0.0 0.4 4.8 0.0 0.0 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 3.2 0.6 0.1 0.0 0.4 0.0 0.1 2.3 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.1 1.7 0.2 0.0 0.0 0.2 0.2 0.8 3.1 0.1 0.5 2.2 0.1 0.1 0.5 0.0 0.0 0.0 1.5 0.0 4.5 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.1 0.0 1.7 0.0 0.0 2.2 3.7 1.9 2.7 2.5 1.8 2.3 2.0 4.0 2.9 NADK FLJ13052 ENSG00000008130 "NAD kinase" O95544 1 1751232-1780457 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 80.4" "Group enriched" "Detected in many" 7 "granulocytes: 80.4;monocytes: 24.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048909, HPA053368" Uncertain Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA048909: , HPA053368: " "unprognostic (1.29e-1)" "unprognostic (4.29e-1)" "unprognostic (7.07e-2)" "unprognostic (6.82e-2)" "unprognostic (1.98e-1)" "unprognostic (1.58e-2)" "unprognostic (3.32e-1)" "unprognostic (9.03e-2)" "unprognostic (7.81e-2)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (4.54e-3)" "unprognostic (1.40e-1)" "unprognostic (5.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-1)" 24.7 34.3 11.1 19.0 11.9 49.0 25.5 9.9 12.6 12.4 18.2 10.8 14.1 20.3 13.9 14.5 12.5 14.3 17.1 11.9 9.9 7.9 12.7 52.3 17.5 27.0 15.8 8.6 16.9 32.2 8.3 11.9 22.5 10.3 13.7 14.1 13.9 21.4 14.5 10.6 11.7 19.4 14.4 8.3 39.4 22.1 17.3 9.6 10.8 14.0 12.0 19.2 13.7 28.3 1.8 7.2 80.4 24.7 0.5 1.4 10.4 15.1 14.6 13.1 19.2 18.7 13.6 16.9 15.3 13.4 17.5 15.6 15.6 27.9 20.1 11.7 11.3 12.9 14.0 12.1 7.8 19.5 22.3 16.4 22.9 26.9 18.1 23.0 27.7 15.9 11.0 10.8 15.5 16.9 20.1 28.8 13.0 17.4 17.3 20.0 8.9 16.6 22.1 11.2 41.1 15.1 12.6 17.7 13.5 17.1 37.7 15.7 13.0 16.1 16.3 12.8 9.2 13.1 13.7 25.7 11.6 45.0 12.6 25.6 6.6 11.8 21.1 49.5 1.2 24.7 1.4 1.8 0.7 0.9 7.2 1.7 0.5 0.7 80.4 0.5 23.8 5.9 1.0 10.4 11.1 11.9 9.9 12.6 9.9 7.9 15.8 8.6 10.3 9.6 NADK2 "C5orf33, FLJ30596, MNADK, NADKD1" ENSG00000152620 "NAD kinase 2, mitochondrial" Q4G0N4 5 36192592-36242279 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 128.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038366, HPA038367, HPA061492" Enhanced 28000 "HPA038366: AB_2675977, HPA038367: AB_10672743, HPA061492: " "unprognostic (1.15e-2)" "unprognostic (2.63e-2)" "unprognostic (3.01e-2)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (1.97e-2)" "unprognostic (4.06e-3)" "unprognostic (8.84e-2)" "unprognostic (3.32e-2)" "unprognostic (1.93e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (9.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.58e-1)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" 5.7 10.2 13.7 4.1 12.5 4.4 6.8 6.7 13.4 6.6 6.0 13.3 5.9 7.0 5.9 4.1 4.9 6.0 5.5 8.3 14.3 8.5 10.0 128.6 4.0 4.2 11.6 12.0 8.8 12.2 4.8 3.1 7.2 11.6 9.5 6.2 3.9 5.6 7.7 11.1 3.3 5.5 24.8 20.3 3.8 7.6 7.3 11.4 2.5 7.6 3.5 5.1 15.2 5.9 5.1 3.3 9.1 4.2 9.5 3.2 1.7 8.9 5.9 9.0 10.3 13.8 11.8 12.3 8.4 5.6 7.8 5.7 16.5 11.3 32.2 6.3 9.6 6.3 8.4 6.1 10.8 8.9 7.4 8.6 17.4 9.6 10.1 18.7 3.5 12.9 9.5 8.5 12.9 8.1 22.7 11.6 7.7 3.6 17.4 7.2 5.0 8.5 16.9 22.3 6.9 9.9 7.7 4.0 9.2 43.4 13.8 4.5 9.8 16.4 6.1 15.1 8.2 11.3 10.0 10.5 12.7 9.5 6.4 24.3 5.9 9.1 2.0 1.9 2.1 2.0 2.7 2.2 3.2 2.5 3.3 5.1 2.7 2.2 0.1 9.5 4.2 1.5 2.9 1.7 13.7 12.5 6.7 11.4 14.3 8.5 11.6 12.0 11.6 11.4 NADSYN1 FLJ10631 ENSG00000172890 "NAD synthetase 1" Q6IA69 11 71453109-71524107 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017798, HPA038523, HPA038524" Approved Approved "Golgi apparatus,Vesicles,Cytosol" Vesicles "Golgi apparatus, Cytosol" "CAB017798: , HPA038523: , HPA038524: " "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" "unprognostic (7.30e-2)" "unprognostic (2.63e-3)" "unprognostic (1.75e-1)" "unprognostic (1.60e-1)" "prognostic unfavourable (5.17e-6)" "unprognostic (1.19e-2)" "unprognostic (4.38e-2)" "unprognostic (1.41e-1)" "unprognostic (9.41e-2)" "unprognostic (1.99e-2)" "prognostic unfavourable (8.72e-5)" "unprognostic (4.12e-3)" "unprognostic (1.38e-1)" "unprognostic (1.54e-2)" "prognostic favourable (5.10e-4)" 14.5 16.9 10.8 23.2 21.2 39.6 14.0 12.2 18.5 12.4 30.6 21.9 24.1 26.3 15.0 17.5 29.1 16.4 33.1 10.6 10.4 9.5 16.5 24.8 18.1 20.5 22.7 9.2 15.6 20.6 13.5 20.2 17.1 15.6 23.9 25.3 12.9 18.0 17.2 9.8 15.0 36.8 13.6 14.6 30.7 19.2 17.4 20.0 26.4 17.3 21.7 29.8 26.1 17.1 9.5 22.3 12.8 19.7 11.9 12.6 13.1 6.1 14.9 4.8 8.8 14.6 21.4 13.3 12.1 10.9 6.3 6.9 12.7 10.5 5.4 13.7 14.1 22.1 6.3 17.2 3.3 10.9 5.1 8.8 10.0 14.2 18.3 17.6 17.0 30.3 27.1 8.1 7.4 22.1 4.5 7.6 8.9 19.3 8.6 11.5 2.9 8.7 10.8 15.3 5.3 15.5 28.6 3.6 5.2 8.6 11.3 22.0 10.0 9.6 26.6 7.0 6.0 12.7 4.6 9.8 4.2 4.6 12.3 10.1 4.8 4.5 19.7 11.8 11.7 17.4 9.9 9.5 10.5 10.6 22.3 7.4 7.0 8.8 12.8 11.9 15.1 16.7 12.6 13.1 10.8 21.2 12.2 18.5 10.4 9.5 22.7 9.2 15.6 20.0 NAGA D22S674 ENSG00000198951 Alpha-N-acetylgalactosaminidase P17050 22 42058354-42070842 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "classical monocyte: 38.5;intermediate monocyte: 47.6;myeloid DC: 37.9;non-classical monocyte: 46.1;plasmacytoid DC: 23.2" "Group enriched" "Detected in all" 9 "dendritic cells: 37.9;monocytes: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000649 Enhanced "Intracellular and membrane" 2300000 "HPA000649: AB_1079448" "unprognostic (3.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.45e-3)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (4.27e-1)" "unprognostic (1.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.93e-1)" "unprognostic (3.64e-2)" "unprognostic (3.68e-2)" "unprognostic (1.92e-3)" "unprognostic (8.95e-2)" "unprognostic (2.53e-1)" 23.7 13.5 12.1 20.3 14.5 11.3 12.5 11.8 10.3 16.3 18.3 15.0 10.7 13.2 18.9 16.1 14.5 17.3 16.5 15.8 10.1 8.6 17.9 28.2 19.9 32.6 12.6 7.3 18.1 9.5 27.8 13.1 45.3 11.5 15.2 18.0 19.8 16.6 14.5 9.2 9.9 25.6 18.7 11.4 22.0 14.1 9.3 13.2 12.0 15.0 11.4 17.9 17.3 14.5 2.1 37.9 4.9 47.6 3.4 3.4 19.2 9.0 4.6 7.4 13.1 12.9 14.8 5.4 7.5 15.4 12.9 13.5 10.3 13.4 4.4 4.6 16.2 6.4 5.6 9.1 7.7 10.1 7.1 10.9 7.1 6.9 7.5 9.0 65.2 10.1 8.0 11.6 4.9 21.3 4.0 18.9 10.2 10.5 3.3 3.7 1.9 6.2 7.5 3.7 7.8 10.0 10.8 2.3 2.6 9.9 9.1 9.8 13.6 16.7 11.4 9.1 11.1 5.8 6.7 10.5 10.5 3.5 9.7 17.3 11.2 4.9 38.5 4.6 2.8 47.6 2.8 2.1 2.9 2.6 37.9 1.5 1.9 1.8 1.9 3.4 46.1 23.2 3.4 19.2 12.1 14.5 11.8 10.3 10.1 8.6 12.6 7.3 11.5 13.2 NAGK GNK ENSG00000124357 "N-acetylglucosamine kinase" Q9UJ70 2 71064344-71079805 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035206, HPA035207" Enhanced Approved Nucleoplasm,Cytosol 690000 Cytosol Nucleoplasm "HPA035206: AB_2674517, HPA035207: AB_10602031" "unprognostic (6.15e-2)" "unprognostic (4.23e-3)" "unprognostic (2.97e-2)" "prognostic unfavourable (6.88e-4)" "unprognostic (2.44e-1)" "prognostic favourable (5.87e-4)" "unprognostic (4.65e-3)" "unprognostic (2.18e-2)" "unprognostic (2.31e-1)" "unprognostic (9.99e-2)" "unprognostic (4.32e-2)" "unprognostic (1.59e-1)" "prognostic unfavourable (4.35e-4)" "unprognostic (8.60e-2)" "unprognostic (1.45e-2)" "unprognostic (5.50e-3)" "unprognostic (2.13e-2)" 20.0 17.6 21.8 30.9 24.5 9.8 15.7 13.9 18.8 23.6 15.5 23.7 17.4 11.4 16.4 19.7 67.0 13.7 20.0 14.0 17.6 20.4 16.9 20.2 18.3 30.6 31.1 20.3 15.0 25.8 27.5 21.8 43.9 26.2 15.8 15.8 14.7 49.0 17.8 11.3 29.5 14.6 22.8 21.6 43.4 15.5 24.8 26.7 20.2 13.0 27.2 39.9 24.5 26.1 14.3 53.0 37.4 79.3 8.5 7.1 52.2 18.8 15.3 8.6 8.8 34.5 21.1 33.9 42.1 18.2 28.2 25.7 17.9 9.9 10.5 10.1 29.2 9.1 6.6 12.5 17.5 15.0 5.2 5.9 5.0 11.1 25.9 3.7 15.1 18.9 13.1 30.3 4.7 29.6 2.7 11.9 39.1 17.3 9.3 13.2 9.2 11.9 7.3 24.1 5.4 17.1 33.8 9.0 4.9 12.7 20.1 13.2 10.4 4.7 26.0 33.7 13.1 13.0 14.7 8.3 7.2 6.2 23.0 10.1 18.4 10.3 79.3 31.5 5.4 69.8 5.5 14.3 6.4 5.2 53.0 13.3 5.5 4.5 37.4 8.5 46.6 42.4 7.1 52.2 21.8 24.5 13.9 18.8 17.6 20.4 31.1 20.3 26.2 26.7 NAGLU NAG ENSG00000108784 N-acetyl-alpha-glucosaminidase P54802 17 42536172-42544449 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Charcot-Marie-Tooth disease, Disease mutation, Mucopolysaccharidosis, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038815 Supported "Intracellular and membrane" 300000000 "HPA038815: AB_10697398" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (6.48e-2)" "prognostic favourable (4.17e-4)" "prognostic unfavourable (6.59e-4)" "unprognostic (1.46e-1)" "unprognostic (1.75e-3)" "unprognostic (3.09e-2)" "unprognostic (2.20e-1)" "unprognostic (6.68e-2)" "prognostic favourable (6.90e-4)" "unprognostic (8.07e-2)" "prognostic favourable (2.58e-6)" "unprognostic (2.25e-1)" "unprognostic (8.74e-3)" "unprognostic (2.15e-2)" "unprognostic (1.62e-1)" 21.1 21.0 10.2 8.4 15.9 10.7 18.3 5.5 11.4 16.9 17.1 19.1 16.3 14.8 19.3 20.6 11.9 14.6 21.4 11.5 10.7 5.9 31.3 50.1 16.3 12.5 21.6 8.0 20.4 38.9 10.6 12.7 23.5 12.1 14.8 10.2 20.9 32.4 12.3 9.1 13.2 17.3 10.1 13.5 22.5 17.0 9.8 20.5 8.9 20.7 8.9 12.3 16.1 12.7 4.8 6.0 3.8 5.8 4.3 5.8 2.4 5.9 20.9 4.2 9.5 41.9 13.9 14.2 9.1 21.7 9.6 12.3 5.6 15.5 7.7 9.3 14.0 14.6 3.7 4.4 2.1 5.9 7.7 4.1 10.9 11.6 14.0 5.0 10.9 16.5 6.8 5.2 6.6 12.5 6.1 15.5 10.6 14.4 0.8 8.6 4.9 2.7 3.2 9.1 17.8 12.7 13.8 6.3 9.6 5.0 6.9 7.7 31.8 5.3 9.7 23.4 3.9 9.3 5.9 20.6 9.3 6.4 14.3 5.4 16.6 2.3 5.5 3.8 5.6 3.7 5.8 4.8 2.4 3.1 4.5 4.6 4.3 3.5 2.5 4.3 5.8 6.0 0.5 2.4 10.2 15.9 5.5 11.4 10.7 5.9 21.6 8.0 12.1 20.5 NAGPA "APAA, UCE" ENSG00000103174 "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase" Q9UK23 16 5024844-5034141 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064055 Approved 3600000 "HPA064055: " "unprognostic (9.93e-2)" "unprognostic (1.61e-2)" "unprognostic (2.08e-2)" "unprognostic (2.21e-2)" "unprognostic (7.12e-3)" "unprognostic (3.30e-3)" "prognostic unfavourable (4.67e-4)" "unprognostic (1.05e-2)" "unprognostic (2.98e-2)" "unprognostic (1.35e-1)" "unprognostic (9.51e-3)" "unprognostic (9.41e-2)" "prognostic unfavourable (2.67e-5)" "unprognostic (1.26e-1)" "unprognostic (6.09e-2)" "unprognostic (7.47e-2)" "unprognostic (1.02e-1)" 8.3 6.3 9.9 9.0 20.1 8.7 4.7 4.7 25.0 6.8 8.5 4.6 5.8 11.4 6.2 4.7 6.1 4.8 5.6 5.0 15.3 5.3 7.2 7.6 7.6 9.1 5.0 9.5 4.2 7.3 7.6 4.9 6.8 6.6 4.9 5.1 4.0 6.0 6.2 6.7 8.5 9.2 5.5 4.4 10.9 12.4 2.7 5.5 4.3 5.1 2.6 5.6 6.0 4.4 9.5 26.5 5.1 20.9 5.1 9.9 9.7 1.5 5.9 1.0 6.4 2.5 3.3 6.7 4.4 7.9 5.8 7.3 4.9 12.3 0.6 5.6 6.0 4.6 2.7 4.9 1.7 7.2 8.3 2.1 3.8 31.8 8.2 5.3 9.3 5.0 5.1 3.8 1.7 9.0 6.8 8.8 3.5 6.7 2.4 14.2 3.1 6.3 6.4 2.4 11.6 3.7 2.3 2.6 3.5 3.5 8.8 9.0 6.0 6.5 6.6 6.4 4.6 14.8 3.3 4.8 3.7 1.4 3.0 8.1 5.3 1.2 20.9 5.1 9.9 18.2 7.9 9.5 9.8 8.8 26.5 8.3 8.1 7.4 0.6 5.1 11.7 6.8 8.7 9.7 9.9 20.1 4.7 25.0 15.3 5.3 5.0 9.5 6.6 5.5 NAGS "AGAS, ARGA, NAT7" ENSG00000161653 "N-acetylglutamate synthase" Q8N159 17 44004546-44009063 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Urea cycle" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.4;liver: 30.2" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.3;HHSteC: 6.4;TIME: 7.9;U-87 MG: 11.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA027300 Supported Mitochondria "Intracellular and membrane" Mitochondria "HPA027300: " "unprognostic (1.51e-3)" "unprognostic (9.24e-2)" "unprognostic (1.68e-1)" "unprognostic (8.67e-2)" "unprognostic (1.44e-2)" "unprognostic (1.30e-3)" "unprognostic (2.38e-2)" "unprognostic (1.98e-1)" "unprognostic (3.14e-2)" "unprognostic (2.73e-2)" "unprognostic (2.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.19e-2)" "unprognostic (6.99e-2)" "unprognostic (1.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" 0.6 0.6 0.5 0.4 2.4 0.0 1.0 0.7 1.5 0.3 7.2 0.5 5.6 16.4 0.5 2.6 0.9 0.3 0.3 0.9 0.7 1.5 4.4 30.2 2.5 0.2 1.8 0.6 0.5 0.3 3.6 0.4 0.4 1.2 0.8 0.4 0.1 0.9 6.5 0.1 0.6 13.4 0.3 2.0 0.5 0.3 0.4 1.1 0.2 2.9 0.0 0.1 0.8 0.8 1.5 2.0 2.3 2.7 1.0 3.5 1.3 3.4 0.2 0.0 0.5 0.0 6.3 0.1 0.6 0.0 0.2 0.0 2.2 0.8 0.0 1.3 0.0 1.4 0.0 1.2 0.1 0.3 0.8 0.1 0.2 2.6 6.4 0.0 0.0 2.7 0.1 0.2 0.0 1.2 0.2 0.0 0.0 0.1 0.0 0.0 0.4 2.6 0.1 0.2 0.0 0.0 0.0 2.6 0.0 1.2 0.0 0.0 0.2 0.1 7.9 3.0 0.8 0.2 0.7 0.2 0.2 0.2 11.9 0.1 0.4 1.8 1.4 2.3 3.5 1.5 2.8 1.2 2.2 2.9 2.0 1.5 1.1 1.7 0.8 1.0 2.7 0.3 1.7 1.3 0.5 2.4 0.7 1.5 0.7 1.5 1.8 0.6 1.2 1.1 NAMPT "PBEF, PBEF1" ENSG00000105835 "Nicotinamide phosphoribosyltransferase" P43490 7 106248285-106286326 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Biological rhythms, Pyridine nucleotide biosynthesis" "Cytokine, Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 108.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 18 "neutrophil: 143.5" "Lineage enriched" "Detected in many" 20 "granulocytes: 143.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034349, HPA047776, HPA057722" Approved Approved "Nuclear speckles,Cell Junctions" "Secreted to blood" 2140000 410000 "Nuclear speckles" "Cell Junctions" "CAB034349: AB_2251220, HPA047776: , HPA057722: " "unprognostic (2.87e-1)" "prognostic unfavourable (4.78e-4)" "unprognostic (5.90e-3)" "unprognostic (1.63e-2)" "unprognostic (1.50e-2)" "prognostic unfavourable (8.81e-4)" "unprognostic (2.15e-1)" "unprognostic (2.74e-2)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "prognostic unfavourable (1.51e-4)" "unprognostic (3.02e-1)" "prognostic unfavourable (2.49e-6)" "unprognostic (6.83e-2)" "unprognostic (6.96e-2)" "unprognostic (7.76e-2)" "unprognostic (6.44e-3)" 67.3 22.2 8.1 113.6 18.1 110.4 52.6 7.8 12.9 11.6 18.2 2.9 9.5 9.3 9.9 13.5 53.4 27.8 28.1 84.4 13.4 6.3 13.5 92.9 48.9 117.5 10.3 5.2 27.3 18.3 5.5 10.0 23.9 29.2 17.4 10.5 8.2 32.9 14.3 41.0 12.9 14.1 44.9 59.1 41.1 26.4 11.9 7.1 6.2 13.5 40.7 13.2 48.8 26.4 0.8 2.0 143.5 7.3 1.0 1.5 1.3 18.9 12.6 4.6 7.6 19.4 22.6 7.5 6.0 34.0 12.2 21.6 7.4 11.5 15.9 14.4 6.7 15.0 8.4 18.1 26.8 9.4 9.1 6.4 5.4 5.8 72.5 12.4 11.9 21.6 20.7 21.8 25.5 38.8 13.4 60.9 14.5 9.9 12.3 5.2 8.8 10.2 5.9 6.5 34.9 11.6 17.8 9.3 5.1 8.4 18.5 21.4 5.9 3.6 33.0 18.2 14.1 26.1 11.0 42.0 23.8 22.8 108.1 14.1 26.9 8.1 2.3 3.5 0.4 5.6 0.7 0.8 0.5 0.6 2.0 0.7 0.8 0.4 143.5 1.0 7.3 0.8 1.5 1.3 8.1 18.1 7.8 12.9 13.4 6.3 10.3 5.2 29.2 7.1 NANP "C20orf147, dJ694B14.3, HDHD4, MGC26833" ENSG00000170191 "N-acetylneuraminic acid phosphatase" Q8TBE9 20 25612935-25624175 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050342 Uncertain Approved "Nuclear membrane" "Nuclear membrane" "HPA050342: AB_2681098" "unprognostic (8.72e-2)" "unprognostic (1.88e-1)" "unprognostic (7.42e-3)" "unprognostic (6.01e-2)" "unprognostic (5.59e-2)" "unprognostic (2.12e-1)" "prognostic unfavourable (9.01e-6)" "unprognostic (3.20e-1)" "unprognostic (3.75e-2)" "unprognostic (7.70e-3)" "unprognostic (1.24e-1)" "unprognostic (3.46e-1)" "unprognostic (2.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.76e-1)" "unprognostic (1.71e-2)" "unprognostic (9.42e-2)" 10.0 14.0 6.3 6.0 7.4 6.9 7.2 13.3 8.2 6.3 6.4 4.1 4.3 7.1 6.9 5.7 9.5 6.2 6.2 6.8 4.3 4.8 11.6 12.5 6.7 4.4 4.2 3.3 12.0 7.4 8.0 8.6 6.0 6.5 5.6 6.2 7.1 7.8 6.1 9.2 4.9 7.6 6.9 5.6 7.1 6.2 6.6 3.7 18.2 9.0 6.0 6.8 7.4 6.8 1.7 6.4 1.7 4.5 4.9 4.2 2.3 11.1 6.5 5.3 7.7 8.6 9.2 7.8 5.7 11.2 7.6 9.7 5.8 7.6 4.0 6.5 10.8 7.1 8.1 8.2 14.8 1.4 4.8 10.0 3.1 15.6 7.2 7.6 3.0 8.0 4.1 8.5 10.9 6.3 8.4 7.2 9.2 6.1 15.0 3.7 3.9 10.2 7.5 11.1 4.9 4.4 6.0 10.2 4.2 6.3 10.2 6.7 4.4 6.5 5.3 12.1 9.0 11.1 8.0 3.8 3.5 10.0 3.4 17.7 7.2 0.4 4.5 1.7 2.8 4.5 4.2 1.4 2.0 2.1 6.4 1.7 1.8 3.1 0.3 4.9 2.4 1.4 1.7 2.3 6.3 7.4 13.3 8.2 4.3 4.8 4.2 3.3 6.5 3.7 NANS SAS ENSG00000095380 "N-acetylneuraminate synthase" Q9NR45 9 98056739-98083075 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019223 Approved Approved Nucleoplasm 200000 Nucleoplasm "HPA019223: AB_1854298" "unprognostic (2.95e-1)" "unprognostic (5.10e-3)" "unprognostic (2.24e-2)" "prognostic favourable (1.71e-4)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "prognostic unfavourable (6.42e-4)" "unprognostic (2.08e-1)" "unprognostic (7.98e-2)" "unprognostic (2.28e-1)" "unprognostic (1.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (7.36e-2)" "unprognostic (3.62e-3)" "unprognostic (1.79e-1)" 17.2 10.1 8.8 20.2 11.4 22.2 16.4 7.0 11.7 20.2 47.6 6.4 17.0 19.4 11.0 15.1 18.6 10.4 25.0 20.9 14.4 12.4 15.0 49.6 17.1 20.1 11.5 10.6 14.1 59.2 6.1 16.3 15.8 12.1 37.2 49.6 9.4 80.0 18.3 11.9 10.3 18.9 11.0 9.0 22.2 28.3 11.5 9.8 10.6 19.7 15.2 25.0 15.7 14.8 12.3 41.9 16.4 49.8 7.4 12.1 18.3 74.0 21.9 6.5 18.8 13.1 14.2 14.1 23.7 18.6 19.4 15.9 26.2 10.6 22.8 11.5 26.0 26.4 12.1 20.4 16.3 18.3 18.0 13.5 24.5 52.1 36.3 15.3 11.1 12.0 13.9 20.6 23.6 20.7 24.5 23.9 14.1 50.9 10.2 22.0 11.2 28.5 19.8 17.8 23.2 15.5 22.8 13.2 6.9 15.2 82.6 20.1 27.4 16.5 53.7 15.2 14.7 38.7 24.3 22.2 18.5 8.7 17.9 18.5 11.8 5.3 42.1 6.0 8.0 49.8 12.1 12.3 10.5 8.3 41.9 10.1 11.5 7.8 16.4 7.4 43.0 38.4 11.9 18.3 8.8 11.4 7.0 11.7 14.4 12.4 11.5 10.6 12.1 9.8 NAPEPLD "C7orf18, FMP30, NAPE-PLD" ENSG00000161048 "N-acyl phosphatidylethanolamine phospholipase D" Q6IQ20 7 103099776-103149560 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019832, HPA024338" Approved Enhanced Cytosol Cytosol "HPA019832: AB_1844422, HPA024338: " "unprognostic (3.62e-1)" "unprognostic (1.86e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.58e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" "unprognostic (6.39e-3)" "unprognostic (2.70e-2)" "unprognostic (1.20e-1)" "unprognostic (2.81e-2)" "unprognostic (3.21e-1)" "prognostic favourable (7.32e-6)" "unprognostic (8.83e-2)" "unprognostic (1.19e-1)" "unprognostic (1.42e-1)" "unprognostic (2.41e-2)" 3.8 5.3 8.6 3.8 14.0 3.1 3.9 13.9 18.5 5.1 8.8 17.2 3.7 15.9 4.9 3.5 2.6 6.5 6.1 4.2 6.4 5.5 15.1 7.4 4.3 3.8 15.0 11.6 9.7 4.1 8.5 6.2 2.9 10.3 5.4 10.1 5.0 4.2 4.1 5.0 5.7 10.8 4.5 9.7 6.6 11.2 11.1 16.7 5.3 8.8 0.9 3.8 6.9 4.6 7.9 3.7 5.7 4.6 2.9 7.6 2.5 4.6 6.2 4.0 3.6 3.6 3.9 0.6 3.0 2.8 2.1 3.4 2.7 6.2 4.2 5.1 2.3 4.3 2.8 1.0 2.5 6.5 3.9 1.7 3.7 1.2 0.9 3.7 1.8 2.2 1.2 1.9 0.0 3.4 2.0 4.5 4.0 1.7 4.4 2.0 3.7 7.3 2.8 1.8 2.2 7.6 2.2 2.9 3.9 8.2 2.6 1.8 1.7 2.1 3.0 5.9 4.2 12.0 3.7 5.6 6.1 3.6 4.2 2.7 11.3 0.2 3.1 5.7 4.9 4.6 4.4 7.4 5.3 5.8 3.7 7.9 7.6 5.6 0.3 2.9 3.0 2.7 4.7 2.5 8.6 14.0 13.9 18.5 6.4 5.5 15.0 11.6 10.3 16.7 NAPRT "NAPRT1, PP3856" ENSG00000147813 "Nicotinate phosphoribosyltransferase" Q6XQN6 8 143574785-143578649 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 21.9;SK-BR-3: 23.5;U-937: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023739, HPA024017, CAB068206, CAB068207" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" 2000000 "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB068206: , CAB068207: , HPA023739: AB_1854308, HPA024017: AB_1854309" "unprognostic (7.08e-2)" "unprognostic (1.55e-1)" "unprognostic (5.76e-3)" "unprognostic (2.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.30e-1)" "unprognostic (7.65e-2)" "unprognostic (2.19e-1)" "unprognostic (2.84e-1)" "unprognostic (1.08e-2)" "unprognostic (1.75e-1)" "unprognostic (4.13e-2)" "prognostic favourable (6.28e-4)" "unprognostic (6.02e-2)" "unprognostic (3.97e-1)" "unprognostic (2.28e-2)" "unprognostic (1.61e-2)" 9.7 6.4 4.9 9.7 6.2 21.1 13.2 10.7 5.4 6.7 25.2 2.3 9.9 33.0 4.7 4.7 16.4 4.8 15.5 4.9 3.9 2.1 10.7 28.3 8.3 12.1 3.7 0.1 5.9 6.5 2.4 2.8 8.6 4.1 6.9 3.8 5.2 12.8 3.8 7.1 12.4 34.4 5.2 2.2 9.8 11.8 5.5 4.0 3.0 6.8 8.9 9.5 7.6 8.1 0.8 4.7 4.6 8.4 0.5 1.6 2.4 3.4 3.9 0.4 0.8 0.3 1.2 2.5 0.8 0.4 1.3 0.8 3.2 21.9 0.9 6.1 0.2 7.5 0.2 6.2 0.0 4.0 6.3 5.2 10.3 0.9 2.8 1.2 2.8 0.1 2.2 0.1 0.0 1.4 4.8 4.1 0.1 4.2 2.5 2.7 1.0 2.5 4.5 0.1 10.8 0.9 1.3 1.7 0.4 9.9 23.5 2.9 0.9 3.0 4.1 0.7 6.2 4.6 1.7 0.5 0.2 1.1 1.1 18.2 3.2 0.0 4.4 4.6 1.6 8.4 0.5 0.8 0.7 1.5 4.7 0.2 0.8 0.7 2.7 0.5 8.4 1.5 0.2 2.4 4.9 6.2 10.7 5.4 3.9 2.1 3.7 0.1 4.1 4.0 NAPSA "KAP, Kdap, NAP1, NAPA" ENSG00000131400 "Napsin A aspartic peptidase" O96009 19 50358477-50365830 "Enzymes, Plasma proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "kidney: 47.5;lung: 153.3" "Cell line enriched" "Detected in some" 24 "U-698: 29.1" "Cancer enriched" "Detected in many" 18 "lung cancer: 249.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 10.5" "Group enriched" "Detected in many" 9 "B-cells: 5.1;dendritic cells: 10.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB009591, HPA045280, HPA047236, HPA047744" Enhanced "Secreted in other tissues" 380000 "CAB009591: , HPA045280: AB_2679283, HPA047236: AB_2679993, HPA047744: AB_2680143" "unprognostic (5.36e-2)" "unprognostic (4.77e-2)" "unprognostic (1.64e-3)" "unprognostic (1.78e-1)" "unprognostic (1.93e-1)" "unprognostic (4.65e-2)" "unprognostic (1.02e-1)" "unprognostic (8.30e-3)" "unprognostic (2.29e-1)" "unprognostic (2.23e-2)" "unprognostic (1.76e-3)" "unprognostic (7.67e-3)" "prognostic favourable (1.21e-4)" "unprognostic (4.08e-4)" "unprognostic (3.29e-1)" "unprognostic (9.83e-3)" "unprognostic (7.26e-5)" 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 5.0 0.1 0.1 0.1 0.1 0.1 0.0 47.5 0.1 153.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.5 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 5.1 10.5 0.5 0.9 0.5 0.6 1.1 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.4 0.2 0.2 0.1 0.5 0.1 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.3 1.2 0.1 0.0 0.0 0.3 0.1 0.0 0.6 0.1 0.3 0.2 0.3 0.6 0.0 0.1 0.9 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.8 0.0 0.2 0.4 29.1 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.9 0.0 5.1 0.2 0.4 3.0 1.9 0.6 0.5 0.5 0.5 0.9 10.5 0.0 1.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.1 NARS NARS1 ENSG00000134440 "Asparaginyl-tRNA synthetase" O43776 18 57600656-57622213 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034257, HPA040017" Enhanced Supported Cytosol Cytosol "CAB034257: AB_2151043, HPA040017: " "unprognostic (9.85e-2)" "unprognostic (1.88e-1)" "unprognostic (3.86e-3)" "unprognostic (1.68e-1)" "unprognostic (2.61e-1)" "unprognostic (1.28e-1)" "prognostic unfavourable (1.23e-7)" "unprognostic (1.78e-1)" "unprognostic (1.48e-1)" "unprognostic (1.62e-2)" "unprognostic (1.98e-1)" "unprognostic (8.82e-2)" "prognostic favourable (1.73e-7)" "unprognostic (1.24e-2)" "unprognostic (1.30e-1)" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" 30.9 36.9 35.0 28.8 42.6 19.5 31.6 47.1 51.4 28.1 49.7 24.8 31.1 42.5 30.8 31.6 40.2 27.4 26.8 40.6 40.5 36.5 66.0 41.9 26.0 23.0 39.5 39.2 29.4 29.4 52.0 35.7 25.6 49.5 33.1 46.1 18.5 33.7 30.9 76.6 26.9 35.2 29.9 40.6 25.7 36.0 14.9 36.3 25.0 44.5 31.9 29.2 34.6 35.3 20.0 26.6 15.6 40.8 15.8 23.4 23.7 35.9 23.8 22.4 32.7 28.8 22.1 34.9 50.3 26.3 29.7 36.9 17.1 16.9 45.4 24.2 34.8 41.0 35.2 31.1 43.6 22.0 12.2 34.7 18.3 26.9 48.7 71.9 35.9 23.4 54.5 40.7 39.0 24.6 42.6 33.9 33.3 13.4 27.8 17.4 32.9 19.1 22.1 26.4 38.3 55.6 40.6 24.6 27.0 24.4 31.5 52.8 17.6 40.0 26.9 33.2 22.2 14.0 37.2 76.1 94.1 44.1 30.5 47.3 38.6 15.6 40.8 14.2 16.4 35.1 20.2 20.0 17.3 17.4 26.6 18.8 23.4 21.2 12.7 15.8 26.6 25.1 17.2 23.7 35.0 42.6 47.1 51.4 40.5 36.5 39.5 39.2 49.5 36.3 NARS2 "DFNB94, FLJ23441, SLM5" ENSG00000137513 "Asparaginyl-tRNA synthetase 2, mitochondrial" Q96I59 11 78435961-78574874 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease mutation, Leigh syndrome, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026793 Supported Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria" Cytosol "HPA026793: AB_1848833" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (5.73e-3)" "unprognostic (1.79e-3)" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (5.62e-2)" "unprognostic (4.62e-3)" "prognostic favourable (1.39e-5)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "prognostic favourable (1.22e-6)" "unprognostic (8.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" 10.9 16.0 11.8 9.3 11.2 6.4 13.4 19.4 11.8 11.6 13.0 13.1 13.5 12.0 17.6 13.9 10.8 12.0 9.9 12.7 11.3 12.2 22.3 26.8 9.0 10.2 13.4 8.4 15.9 20.0 14.0 17.3 9.4 13.8 13.3 13.3 23.2 12.7 13.2 24.4 9.1 11.1 10.6 10.8 12.6 11.3 11.8 10.3 17.3 16.0 7.7 14.1 9.7 10.7 14.6 13.5 6.7 9.4 16.2 16.6 8.7 7.4 10.5 11.0 7.2 7.7 6.5 9.2 6.2 6.1 9.7 8.0 17.9 8.1 18.5 16.2 3.9 9.9 18.5 12.1 13.5 12.1 9.9 13.0 8.1 15.2 6.4 13.9 4.8 4.5 7.8 8.5 15.2 8.3 19.6 5.1 10.8 8.7 14.4 22.6 12.0 12.7 15.1 18.0 25.0 12.9 10.6 13.1 8.3 9.2 11.9 15.9 11.2 5.5 5.0 13.2 15.6 15.0 10.4 8.5 14.3 40.8 2.5 12.6 8.9 6.7 7.9 3.5 9.8 8.3 12.0 14.6 11.3 10.8 13.5 12.6 16.6 14.8 1.7 16.2 9.4 10.3 8.2 8.7 11.8 11.2 19.4 11.8 11.3 12.2 13.4 8.4 13.8 10.3 NAT1 AAC1 ENSG00000171428 "N-acetyltransferase 1" P18440 8 18170477-18223689 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 23.4" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in all" 14 "breast cancer: 47.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB017782, HPA043704" Approved "CAB017782: , HPA043704: " "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "prognostic favourable (5.07e-4)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (8.25e-2)" "unprognostic (5.20e-2)" "unprognostic (6.53e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-2)" "unprognostic (9.51e-2)" "unprognostic (6.60e-2)" "unprognostic (7.44e-2)" "unprognostic (2.30e-1)" "unprognostic (3.28e-2)" "unprognostic (8.15e-2)" 3.7 3.2 1.5 8.5 1.5 1.9 7.9 1.3 1.5 5.4 15.6 1.0 5.1 9.3 4.4 13.0 4.8 3.5 5.9 2.9 1.7 1.0 8.6 14.3 6.2 6.6 2.5 1.0 3.3 4.2 1.1 4.6 6.0 3.1 7.4 10.3 4.5 3.6 5.4 2.0 1.6 23.4 2.6 2.3 9.8 4.8 4.1 0.5 10.8 2.6 4.3 6.2 3.1 3.0 6.3 8.1 12.3 7.1 8.6 8.5 3.9 18.8 2.4 2.1 2.8 5.7 5.8 4.6 6.9 7.2 7.7 8.9 3.1 4.0 9.1 5.5 4.4 3.0 3.8 4.5 7.9 8.6 2.0 6.2 2.6 2.4 5.5 2.8 8.6 4.7 5.8 5.2 0.5 6.7 5.4 2.6 8.5 3.4 8.1 8.8 2.1 2.9 4.0 2.1 3.8 8.2 11.0 1.1 1.4 0.3 8.1 4.7 6.7 8.3 6.8 4.6 2.7 7.0 1.1 1.7 3.3 8.0 4.1 6.3 2.1 5.3 6.4 12.3 4.8 7.1 3.5 6.3 5.0 4.8 8.1 5.4 4.8 5.8 11.2 8.6 6.8 4.7 8.5 3.9 1.5 1.5 1.3 1.5 1.7 1.0 2.5 1.0 3.1 0.5 NAT2 AAC2 ENSG00000156006 "N-acetyltransferase 2" P11245 8 18391245-18401218 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "intestine: 28.4;liver: 75.5" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 2.8;RT4: 4.1;SCLC-21H: 5.7;SK-BR-3: 3.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0;liver cancer: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043704 Uncertain "HPA043704: " "unprognostic (2.74e-3)" "unprognostic (4.03e-1)" "prognostic favourable (4.61e-5)" "unprognostic (1.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.52e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-3)" "unprognostic (1.02e-1)" "unprognostic (3.40e-1)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" 0.2 0.1 0.2 2.3 0.3 0.0 0.3 0.1 0.2 0.3 14.0 0.1 0.1 13.0 0.4 0.4 0.1 0.2 0.3 0.4 0.1 0.1 0.6 75.5 0.2 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.2 0.3 0.3 5.1 0.1 0.1 0.1 0.1 0.1 28.4 0.4 0.2 0.6 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.3 0.0 1.7 0.0 0.1 0.0 1.4 0.0 0.0 0.2 0.3 0.1 0.5 0.1 0.5 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 1.0 0.0 0.0 0.1 1.0 0.0 0.0 0.9 0.0 2.8 4.1 5.7 0.1 0.1 3.6 0.0 1.0 0.5 1.5 1.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.2 0.1 0.1 0.2 0.2 0.3 0.1 NAT8 "ATase2, GLA, Hcml1, TSC501" ENSG00000144035 "N-acetyltransferase 8 (putative)" Q9UHE5 2 73640832-73642393 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 140.4" "Cell line enriched" "Detected in some" 15 "Hep G2: 16.5" "Cancer enriched" "Detected in some" 5 "renal cancer: 242.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA067855, HPA074519" Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA067855: , HPA074519: " "unprognostic (4.51e-2)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (4.95e-3)" "unprognostic (2.46e-1)" "unprognostic (1.90e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (8.60e-2)" "unprognostic (1.37e-3)" "unprognostic (2.07e-2)" "unprognostic (4.11e-3)" "unprognostic (2.13e-2)" "unprognostic (8.36e-5)" 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.7 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.0 140.4 15.8 0.2 0.2 0.2 0.2 0.3 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 1.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 16.5 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 NAT8L "FLJ37478, Hcml3" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059512-2069089 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 45.9;brain: 45.9;testis: 11.8" "Cell line enhanced" "Detected in many" "NB-4: 14.4;SCLC-21H: 18.6;SK-MEL-30: 14.8" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 28 "plasmacytoid DC: 3.8" "Lineage enriched" "Detected in single" 28 "dendritic cells: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria Mitochondria "HPA040677: AB_10794745" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavourable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" 45.9 2.0 23.5 1.3 28.3 1.2 7.9 16.4 45.9 1.2 1.5 7.4 0.3 1.3 1.6 2.8 1.3 2.4 1.3 2.1 20.8 12.9 8.2 1.2 1.2 1.4 16.4 12.6 1.4 3.9 1.2 5.6 1.3 12.8 2.4 1.3 1.2 3.8 3.2 7.3 2.4 1.5 1.4 6.5 1.5 1.6 11.8 8.2 0.0 1.6 0.0 1.2 1.2 0.1 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.0 6.5 3.6 7.2 0.7 0.0 4.1 0.1 0.0 0.2 0.0 2.9 0.2 0.0 1.3 0.0 0.1 8.0 0.0 0.1 0.0 9.4 0.1 1.4 4.6 1.2 9.9 4.9 0.0 0.1 0.0 0.0 0.0 7.7 0.0 0.2 4.3 0.1 14.4 10.1 2.9 0.5 1.7 0.2 0.1 0.3 18.6 6.2 4.7 0.0 14.8 0.5 5.8 0.0 0.0 2.4 0.1 3.8 0.0 0.0 0.1 0.0 4.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 23.5 28.3 16.4 32.7 20.8 12.9 16.4 12.6 12.8 8.2 NAV2 "FLJ10633, FLJ11030, FLJ23707, HELAD1, KIAA1419, POMFIL2, RAINB1" ENSG00000166833 "Neuron navigator 2" Q8IVL1 11 19350724-20121598 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 64.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 34.8;SH-SY5Y: 31.7;TIME: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.9" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011755, HPA011891" Approved Supported Nucleoplasm Nucleoplasm "HPA011755: AB_1854319, HPA011891: AB_1854318" "unprognostic (7.71e-2)" "unprognostic (2.37e-1)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.76e-3)" "unprognostic (3.01e-2)" "unprognostic (3.86e-2)" "unprognostic (1.54e-1)" "unprognostic (1.00e-1)" "unprognostic (3.53e-3)" "unprognostic (1.84e-1)" "unprognostic (2.83e-2)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (6.43e-2)" "unprognostic (3.28e-2)" 14.8 3.1 7.9 4.7 12.5 3.1 13.8 13.8 16.1 10.2 17.6 16.1 8.6 5.1 9.3 13.4 7.8 5.7 3.2 64.6 9.9 7.0 12.3 18.7 11.2 3.0 16.5 11.5 4.7 10.8 10.1 6.6 16.2 23.5 7.9 6.3 8.6 16.5 11.8 3.4 7.9 4.7 13.0 32.2 2.5 9.9 2.1 12.6 0.0 20.1 1.8 5.3 6.0 8.6 0.3 1.9 0.0 0.5 0.0 0.3 0.0 5.9 1.7 3.9 0.4 13.2 8.5 4.2 5.0 8.6 6.6 5.0 6.7 0.8 0.0 0.2 7.5 0.7 0.2 3.9 7.8 1.0 0.4 0.1 8.8 7.6 2.4 0.0 0.2 5.5 10.2 3.1 34.8 8.8 0.7 3.0 19.0 6.3 0.0 0.0 9.2 5.0 0.0 18.0 0.9 5.6 1.7 6.8 31.7 3.8 3.0 5.7 0.1 0.0 24.5 15.5 2.3 18.3 4.7 1.0 0.5 0.0 5.3 0.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.5 1.9 0.0 0.0 7.9 12.5 13.8 16.1 9.9 7.0 16.5 11.5 23.5 12.6 NAXD "CARKD, FLJ10769, LP3298" ENSG00000213995 "NAD(P)HX dehydratase" Q8IW45 13 110615460-110639993 "Enzymes, Predicted intracellular proteins" Lyase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010551 Uncertain 230000 "HPA010551: AB_1848669" "unprognostic (1.24e-1)" "unprognostic (5.14e-2)" "unprognostic (1.79e-2)" "prognostic favourable (3.15e-4)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (3.48e-2)" "unprognostic (2.89e-1)" "unprognostic (3.20e-1)" "unprognostic (9.01e-2)" "unprognostic (1.94e-2)" "unprognostic (4.36e-3)" "prognostic favourable (4.63e-5)" "unprognostic (2.19e-2)" "unprognostic (1.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.62e-2)" 9.1 22.8 17.3 10.9 20.5 4.6 12.5 20.4 25.0 11.5 17.2 19.0 18.0 11.6 13.9 15.3 16.3 14.0 13.6 14.7 20.9 12.0 14.3 30.4 12.1 11.7 15.0 19.4 28.8 24.8 12.7 15.2 14.7 14.8 16.5 12.4 12.7 12.7 21.2 15.1 20.8 12.6 13.7 13.8 13.2 16.7 17.9 17.0 9.2 15.5 10.5 9.9 12.7 11.8 7.3 7.6 0.7 6.9 6.2 8.5 6.1 10.9 5.0 8.3 6.4 10.8 6.6 14.3 8.5 8.0 9.3 9.7 17.1 11.3 2.0 9.3 6.6 9.1 4.7 8.9 4.5 8.3 10.5 7.1 15.7 9.5 10.5 9.4 6.7 9.3 16.5 5.9 6.6 9.8 6.0 0.1 7.3 11.9 6.9 18.0 7.5 6.1 2.3 3.2 2.5 9.9 9.4 14.5 8.6 4.9 26.3 5.9 12.0 15.7 5.7 6.3 5.2 0.1 6.7 7.7 5.2 0.1 10.1 2.1 8.2 0.0 5.9 0.5 8.5 6.9 5.4 7.3 7.7 7.6 7.4 6.5 8.3 8.2 0.7 6.2 4.5 7.6 8.4 6.1 17.3 20.5 20.4 25.0 20.9 12.0 15.0 19.4 14.8 17.0 NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591762-156594299 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Isomerase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Enhanced Nucleoplasm,Cytosol "Secreted to blood" 3300000 Nucleoplasm Cytosol "HPA043766: AB_2678660, HPA048164: AB_2680294" "unprognostic (1.27e-1)" "unprognostic (2.34e-2)" "unprognostic (2.49e-1)" "prognostic unfavourable (4.94e-4)" "unprognostic (7.38e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-3)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.08e-3)" "unprognostic (3.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.15e-2)" "unprognostic (8.05e-2)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" 19.1 29.9 31.6 14.4 28.5 12.1 22.6 17.6 42.5 23.0 30.0 31.0 17.4 28.4 28.5 57.9 23.4 29.4 25.8 46.3 28.5 25.0 41.6 41.0 17.2 16.9 33.2 29.3 29.3 37.3 36.3 29.0 21.8 28.8 27.9 26.6 23.0 29.5 36.3 30.9 20.2 25.9 25.0 29.1 17.4 25.0 29.5 22.2 17.7 32.4 19.5 20.4 20.8 18.3 52.4 53.8 12.4 26.5 31.6 32.5 40.6 31.4 41.8 13.4 23.9 17.8 12.2 16.0 10.9 16.6 18.6 19.7 34.8 21.2 21.4 33.0 13.8 30.7 13.3 26.0 13.2 22.5 29.1 17.7 23.8 22.9 20.4 22.2 18.2 12.3 33.6 23.7 22.1 25.3 18.0 19.5 19.0 56.0 24.4 27.0 16.6 32.7 24.6 12.5 56.5 25.2 26.2 32.3 30.8 26.1 49.8 38.3 48.3 32.7 14.7 13.4 20.9 19.0 23.6 50.6 30.5 20.4 18.5 13.2 20.6 4.9 24.1 12.4 31.6 26.5 31.3 52.4 29.2 32.2 21.7 41.7 32.5 30.9 2.9 31.6 20.6 53.8 25.5 40.6 31.6 28.5 17.6 42.5 28.5 25.0 33.2 29.3 28.8 22.2 NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: , HPA070520: " "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" 9.8 10.0 15.3 7.3 18.0 8.9 10.5 15.9 17.1 13.7 8.9 13.5 4.9 12.5 13.0 11.5 10.8 10.0 8.3 8.8 20.8 12.2 11.9 8.8 9.4 8.2 10.8 9.9 17.2 10.3 23.9 16.0 10.1 14.2 9.6 10.1 19.9 10.6 13.0 42.5 9.3 10.9 11.6 9.7 9.6 7.6 11.4 10.7 8.5 7.0 12.2 9.3 9.7 10.8 2.5 5.5 14.2 3.5 3.4 4.1 1.8 6.6 4.9 8.7 4.5 9.6 8.8 13.3 3.5 7.1 4.5 4.0 4.6 2.8 4.8 1.5 6.4 1.6 5.2 3.0 4.9 22.8 7.5 17.2 2.0 1.9 6.0 7.9 14.4 14.0 4.6 4.3 3.5 4.5 10.4 8.0 6.8 4.4 7.0 2.8 4.1 3.3 5.5 40.1 2.4 4.9 9.0 8.0 6.3 8.2 5.0 3.6 6.0 4.0 4.9 7.5 5.9 5.1 3.5 9.3 8.0 8.4 4.3 5.0 3.7 11.0 3.5 6.9 3.8 2.7 4.1 1.8 3.4 4.1 2.6 2.5 3.3 4.0 14.2 3.4 2.8 5.5 3.7 1.8 15.3 18.0 15.9 17.1 20.8 12.2 10.8 9.9 14.2 10.7 NCOA3 "ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1" ENSG00000124151 "Nuclear receptor coactivator 3" Q9Y6Q9 20 47501902-47656877 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009800, HPA024210" Supported Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB009800: AB_2251314, HPA024210: AB_10602011" "unprognostic (7.26e-3)" "unprognostic (1.00e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-2)" "unprognostic (5.78e-2)" "unprognostic (4.33e-2)" "prognostic unfavourable (8.09e-4)" "unprognostic (2.83e-2)" "unprognostic (1.47e-1)" "unprognostic (5.22e-3)" "unprognostic (2.09e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.95e-1)" "unprognostic (2.04e-2)" "unprognostic (4.18e-1)" "unprognostic (1.63e-1)" 20.1 8.9 6.6 34.0 7.4 11.1 15.7 11.9 9.9 12.3 10.1 8.1 9.0 6.7 15.5 8.8 16.7 12.0 8.6 11.5 6.7 4.8 9.1 9.3 17.4 25.8 7.9 4.7 13.3 10.7 13.5 13.5 54.7 7.9 9.7 9.0 10.8 13.5 10.0 32.5 15.0 17.1 11.3 9.5 30.8 11.4 9.2 7.2 17.6 13.5 10.5 33.3 15.1 17.7 13.0 6.7 6.0 7.3 2.7 4.0 3.5 5.7 18.8 5.3 7.2 12.5 14.7 37.3 5.6 8.4 9.6 5.1 9.0 6.4 20.1 3.7 9.6 14.2 4.1 6.9 7.3 10.6 2.2 2.7 5.3 12.5 7.4 2.1 15.0 6.7 19.8 9.1 10.6 6.8 6.2 4.7 5.3 62.6 3.2 3.7 1.8 7.2 6.0 3.7 8.6 5.3 13.6 1.0 1.9 14.1 17.6 6.0 8.1 5.5 11.8 5.7 5.0 6.9 2.4 12.9 11.8 20.7 6.6 2.2 3.8 3.4 5.2 4.0 3.5 7.3 3.2 13.0 3.2 3.1 6.7 10.0 3.7 4.0 6.0 2.7 7.0 5.5 4.0 3.5 6.6 7.4 11.9 9.9 6.7 4.8 7.9 4.7 7.9 7.2 NDST1 "HSST, NST1" ENSG00000070614 "N-deacetylase and N-sulfotransferase 1" P52848 5 150485818-150558211 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Multifunctional enzyme, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 10 "dendritic cells: 5.5;granulocytes: 7.2;monocytes: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060532 Approved 1000000 "HPA060532: " "unprognostic (1.36e-1)" "unprognostic (5.54e-3)" "unprognostic (1.48e-1)" "prognostic unfavourable (6.99e-4)" "unprognostic (1.77e-1)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.47e-2)" "unprognostic (2.73e-1)" "prognostic unfavourable (5.13e-4)" "unprognostic (4.97e-3)" "unprognostic (6.92e-2)" "unprognostic (7.45e-2)" "unprognostic (2.46e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.08e-2)" 26.3 15.5 17.3 9.9 20.2 4.9 21.3 8.6 28.3 12.9 10.2 41.7 7.3 9.3 11.8 10.0 25.5 11.0 16.9 19.6 17.9 14.4 11.4 49.2 25.2 6.1 28.5 13.8 17.3 28.9 16.5 4.7 10.0 26.1 11.3 7.3 10.8 25.4 13.5 15.3 24.9 14.7 14.3 32.8 30.1 10.2 12.6 19.6 1.4 17.3 11.9 9.8 10.5 11.5 0.6 5.5 7.2 6.5 0.1 0.6 2.9 9.8 8.7 14.6 17.7 14.7 14.7 14.7 18.1 23.8 18.1 27.2 25.8 10.4 6.7 18.4 36.0 16.9 7.8 36.7 12.1 0.8 12.2 7.9 5.7 4.0 10.9 5.9 14.5 20.0 15.3 21.8 9.9 24.6 7.5 2.4 17.6 8.3 0.7 1.8 6.8 10.4 11.4 12.2 2.9 10.6 10.0 4.4 15.4 10.9 34.3 14.5 18.3 1.4 12.0 31.0 28.1 13.4 14.8 5.4 1.4 2.5 25.4 9.2 11.9 1.7 6.5 4.4 0.1 2.3 0.0 0.6 0.0 0.6 5.5 0.1 0.1 0.2 7.2 0.1 5.5 0.4 0.0 2.9 17.3 20.2 8.6 28.3 17.9 14.4 28.5 13.8 26.1 19.6 NDST2 "HSST2, NST2" ENSG00000166507 "N-deacetylase and N-sulfotransferase 2" P52849 10 73801911-73811798 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 50.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA051515 Approved Approved Cytosol 72000 Cytosol "HPA051515: " "unprognostic (8.84e-2)" "unprognostic (7.57e-2)" "unprognostic (2.53e-2)" "unprognostic (9.43e-3)" "unprognostic (5.69e-1)" "unprognostic (1.07e-2)" "unprognostic (5.83e-3)" "unprognostic (2.16e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-2)" "unprognostic (2.23e-5)" "unprognostic (1.49e-2)" "unprognostic (4.08e-7)" "unprognostic (3.71e-2)" "unprognostic (3.69e-2)" "unprognostic (5.93e-2)" "unprognostic (9.06e-2)" 12.6 14.6 7.9 19.2 11.3 37.5 11.8 30.2 12.2 16.6 10.7 13.8 13.4 8.9 18.4 14.8 14.4 12.8 15.5 9.3 9.6 8.4 11.0 9.4 14.7 21.9 7.3 8.8 15.1 12.3 17.3 26.5 14.1 9.2 13.6 10.5 14.7 20.1 17.2 16.4 15.1 14.4 13.4 7.5 31.8 11.8 13.5 9.2 35.3 12.2 8.2 19.3 12.3 13.3 3.1 6.8 5.8 5.3 2.2 7.1 3.2 4.3 3.6 7.4 11.4 9.2 10.6 3.8 5.0 10.8 5.8 6.0 1.9 5.3 3.9 3.1 9.6 5.0 3.6 5.3 4.8 10.3 3.6 3.9 2.7 3.0 16.2 4.9 50.2 10.1 6.5 10.1 10.4 7.6 3.6 14.9 7.4 3.3 5.8 5.5 2.1 15.2 3.5 3.7 2.4 5.0 3.0 2.5 4.2 4.5 10.6 3.5 8.1 7.6 12.2 2.9 3.5 3.9 3.6 7.5 3.3 5.1 3.4 7.6 2.3 1.4 5.3 2.1 5.5 3.7 6.5 2.5 4.7 4.8 4.0 3.1 5.6 7.1 5.8 2.2 3.5 6.8 3.1 3.2 7.9 11.3 30.2 12.2 9.6 8.4 7.3 8.8 9.2 9.2 NDST3 HSST3 ENSG00000164100 "N-deacetylase and N-sulfotransferase 3" O95803 4 118033618-118258648 "Enzymes, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 22.2;lymphoid tissue: 6.8;pituitary gland: 7.6" "Cell line enriched" "Detected in single" 19 "MOLT-4: 18.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basal ganglia: 17.0;cerebellum: 22.2;cerebral cortex: 5.7" "Cell type enhanced" "Detected in some" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056189 Uncertain "HPA056189: " "unprognostic (1.95e-2)" "unprognostic (7.58e-2)" "unprognostic (4.34e-3)" "unprognostic (2.55e-7)" "unprognostic (4.05e-2)" "unprognostic (2.18e-2)" "unprognostic (2.86e-3)" "unprognostic (2.32e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-2)" "unprognostic (7.43e-2)" "unprognostic (1.99e-2)" "unprognostic (1.09e-3)" "unprognostic (1.37e-1)" "unprognostic (4.39e-3)" "unprognostic (6.83e-2)" "unprognostic (8.85e-2)" 0.3 2.0 3.2 0.3 17.0 0.6 0.3 22.2 6.9 2.1 0.4 0.0 0.0 0.3 0.4 0.2 0.3 1.3 0.4 0.3 2.3 2.0 0.9 4.6 0.4 0.6 0.9 1.7 0.6 0.2 0.2 7.6 0.4 1.7 0.5 0.4 1.3 0.2 1.2 0.3 0.4 0.4 0.4 0.6 6.8 1.0 0.5 2.4 6.8 0.6 0.0 0.4 0.3 0.3 0.3 0.4 1.3 0.2 0.4 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.9 1.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 1.3 0.4 0.1 0.4 0.0 0.0 3.2 17.0 22.2 5.7 2.3 2.0 0.9 1.7 1.7 2.4 NDST4 ENSG00000138653 "N-deacetylase and N-sulfotransferase 4" Q9H3R1 4 114827763-115113876 "Enzymes, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 34.6" "Cell line enriched" "Detected in some" 4 "RH-30: 17.6" "Not detected" "Not detected" "Region enriched" "Detected in many" 17 "pons and medulla: 34.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011129 Uncertain "HPA011129: AB_1079460" "unprognostic (5.58e-2)" "unprognostic (5.90e-2)" "unprognostic (4.82e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (6.55e-2)" 0.1 0.0 1.3 0.0 1.7 0.0 0.1 0.2 3.4 1.4 0.3 0.3 0.3 0.1 1.5 0.0 0.1 0.1 0.3 0.1 0.7 1.9 0.1 0.0 0.1 0.0 1.3 1.4 5.7 0.1 0.0 0.6 0.0 34.6 1.5 0.1 0.0 0.5 0.6 0.1 0.2 0.1 1.6 1.0 2.5 1.1 0.7 0.0 0.0 0.1 0.1 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.7 0.2 1.7 0.7 1.9 1.3 1.4 34.6 0.0 NDUFAF7 "C2orf56, MidA, PRO1853" ENSG00000003509 "NADH:ubiquinone oxidoreductase complex assembly factor 7" Q7L592 2 37231631-37253403 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 44.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045217 Uncertain "HPA045217: AB_10960395" "unprognostic (6.38e-2)" "unprognostic (2.92e-2)" "unprognostic (2.13e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "prognostic unfavourable (1.48e-4)" "prognostic favourable (3.08e-4)" "unprognostic (5.44e-2)" "unprognostic (1.55e-2)" "unprognostic (9.88e-2)" "unprognostic (8.12e-3)" "unprognostic (5.94e-2)" "unprognostic (3.48e-2)" "unprognostic (1.03e-1)" "unprognostic (5.73e-2)" "unprognostic (8.67e-3)" 7.1 14.3 10.1 7.5 15.9 7.3 8.3 24.1 17.0 9.3 12.6 7.7 6.1 6.4 10.0 11.0 6.7 6.4 8.1 18.3 9.4 9.7 12.2 13.5 6.6 8.3 9.4 10.5 8.8 7.6 9.4 15.2 7.9 14.5 7.7 8.1 7.8 7.0 7.9 21.0 5.8 7.3 9.8 7.2 7.8 7.1 44.4 10.5 8.2 6.4 6.5 7.5 7.8 7.2 8.9 9.9 5.3 8.1 6.9 8.3 4.1 16.0 8.6 10.8 9.7 7.0 15.0 6.1 5.2 8.6 9.3 11.8 18.3 6.9 13.6 6.7 5.0 12.1 13.4 6.8 11.0 9.3 9.8 10.0 10.7 16.6 8.7 9.8 5.2 11.6 11.4 7.7 4.7 14.3 12.2 9.3 5.4 6.0 9.9 10.8 14.3 7.4 9.0 8.5 11.5 12.9 6.0 11.5 9.2 6.8 11.6 11.4 7.0 4.0 2.8 7.8 10.4 9.5 9.7 8.1 4.6 15.4 11.4 13.6 6.6 4.6 8.1 4.5 8.3 7.0 3.8 8.9 7.4 7.1 9.9 7.8 7.4 6.4 5.3 6.9 4.9 8.1 8.3 4.1 10.1 15.9 24.1 17.0 9.4 9.7 9.4 10.5 14.5 10.5 NDUFS1 CI-75k ENSG00000023228 "NADH:ubiquinone oxidoreductase core subunit S1" P28331 2 206114817-206159603 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 99.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064605, CAB070844" Approved Supported Mitochondria Mitochondria "CAB070844: , HPA064605: " "prognostic unfavourable (3.85e-4)" "unprognostic (1.76e-1)" "unprognostic (9.22e-3)" "unprognostic (5.01e-2)" "unprognostic (8.63e-3)" "unprognostic (3.75e-1)" "unprognostic (3.72e-2)" "unprognostic (6.18e-2)" "unprognostic (2.30e-2)" "unprognostic (3.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.28e-1)" "prognostic favourable (1.47e-12)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" "unprognostic (4.73e-2)" 13.9 29.0 12.1 8.3 22.1 7.6 10.3 11.6 26.4 9.1 17.4 16.4 9.2 18.3 9.1 7.7 15.7 7.7 7.3 62.6 11.3 11.7 29.5 30.7 8.3 7.7 13.3 13.8 8.2 9.3 22.1 11.6 10.8 24.2 10.7 18.9 13.5 12.8 10.9 99.5 11.0 19.9 11.1 10.8 8.4 14.9 8.8 11.1 11.2 10.8 34.7 10.5 11.6 9.4 10.7 15.3 15.7 21.4 12.5 16.1 8.9 12.9 13.0 18.8 13.6 17.6 14.3 21.9 19.1 20.7 31.9 23.2 33.5 15.2 14.7 16.9 23.8 18.2 25.1 18.5 28.4 6.7 11.8 29.4 32.1 30.0 18.3 21.1 13.3 17.4 10.9 25.0 19.7 24.8 31.7 14.9 20.8 16.2 17.4 14.0 17.5 23.1 17.7 26.3 25.4 26.4 23.8 18.4 14.4 22.0 21.6 31.2 19.0 20.5 18.9 17.6 15.7 17.2 18.1 14.4 17.3 21.9 17.7 17.6 18.0 12.0 13.3 15.7 13.6 15.4 10.8 10.7 12.2 13.0 15.3 9.5 10.9 12.4 9.6 12.5 21.4 8.2 16.1 8.9 12.1 22.1 11.6 26.4 11.3 11.7 13.3 13.8 24.2 11.1 NDUFS2 CI-49 ENSG00000158864 "NADH:ubiquinone oxidoreductase core subunit S2" O75306 1 161197104-161214395 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 104.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055140, HPA061953" Enhanced Supported Mitochondria 16000 Mitochondria "HPA055140: AB_2682713, HPA061953: AB_2684646" "unprognostic (2.13e-2)" "unprognostic (2.24e-2)" "unprognostic (8.47e-2)" "unprognostic (7.78e-2)" "unprognostic (9.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-2)" "unprognostic (1.51e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-2)" "unprognostic (3.17e-2)" "unprognostic (1.11e-1)" "prognostic favourable (2.32e-4)" "unprognostic (2.35e-1)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (1.82e-1)" 14.6 30.7 16.6 8.0 25.4 10.2 15.5 23.4 25.4 13.0 25.6 17.9 11.7 23.6 12.3 11.2 16.7 14.5 10.6 75.4 17.6 14.8 37.4 52.6 12.8 9.2 28.0 25.0 14.1 14.3 25.6 10.7 11.5 24.1 12.7 27.2 11.4 14.6 14.5 104.9 14.0 22.1 15.7 16.1 13.0 19.4 8.8 25.3 10.4 12.3 37.1 15.1 13.2 10.5 18.9 47.3 26.6 42.2 20.3 29.2 32.4 18.0 29.1 18.4 21.3 27.0 24.0 15.9 16.4 24.1 32.4 25.6 31.8 18.8 22.9 30.9 25.2 24.2 29.3 29.3 28.7 15.2 24.7 22.4 21.8 27.8 28.0 24.2 20.8 34.6 25.9 26.2 30.0 37.1 28.6 12.5 30.4 20.8 15.3 12.9 33.5 26.8 13.3 19.0 32.2 38.5 21.6 19.5 29.0 19.8 48.9 27.9 44.0 63.4 23.7 15.8 13.5 11.0 22.1 17.6 27.9 19.2 24.1 20.5 20.3 26.6 35.9 18.9 20.5 42.2 19.9 18.9 20.9 20.7 47.3 15.7 21.6 21.8 20.2 20.3 37.0 31.8 29.2 32.4 16.6 25.4 23.4 25.4 17.6 14.8 28.0 25.0 24.1 25.3 NDUFS3 CI-30 ENSG00000213619 "NADH:ubiquinone oxidoreductase core subunit S3" O75489 11 47565336-47584562 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 100.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004484 Approved Supported "Nuclear bodies,Mitochondria" Mitochondria "Nuclear bodies" "HPA004484: AB_1079464" "unprognostic (2.18e-1)" "unprognostic (7.42e-3)" "unprognostic (1.75e-1)" "unprognostic (5.01e-2)" "unprognostic (7.51e-2)" "unprognostic (3.13e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "unprognostic (1.93e-1)" "unprognostic (1.41e-2)" "unprognostic (6.75e-3)" "unprognostic (7.73e-2)" "prognostic favourable (2.61e-6)" "unprognostic (2.77e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-2)" "unprognostic (3.17e-3)" 13.4 22.9 29.7 13.2 46.3 25.5 18.1 23.9 35.0 16.6 28.4 16.5 16.1 31.4 12.7 16.0 19.1 17.3 16.3 45.8 26.0 24.8 34.1 32.0 12.0 13.9 29.4 24.9 12.2 23.0 21.4 17.0 12.0 26.0 13.9 30.9 14.4 20.1 17.4 100.9 15.1 28.9 15.9 17.1 14.2 18.9 15.1 15.4 20.5 16.1 51.6 18.8 14.5 11.7 25.0 36.1 18.7 31.2 16.4 23.8 31.5 11.5 21.9 18.6 19.3 16.1 16.6 15.9 11.0 18.8 27.1 25.8 32.2 20.3 25.6 10.9 15.6 21.3 26.2 19.7 22.1 13.7 42.3 15.5 30.8 31.1 16.5 37.9 20.2 16.2 14.3 10.2 17.0 17.0 22.6 17.8 17.5 35.2 25.9 49.2 26.3 31.0 31.7 26.7 21.1 23.2 18.0 20.8 15.0 14.0 24.1 24.8 26.9 36.3 11.9 16.2 18.2 18.8 24.7 20.4 27.0 28.4 16.5 29.2 16.1 12.2 28.6 18.7 18.7 31.2 19.8 25.0 19.7 20.3 33.7 23.1 18.8 20.1 7.5 16.4 25.0 36.1 23.8 31.5 29.7 46.3 23.9 35.0 26.0 24.8 29.4 24.9 26.0 15.4 NDUFS8 "CI-23k, TYKY" ENSG00000110717 "NADH:ubiquinone oxidoreductase core subunit S8" O00217 11 68030617-68036644 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 156.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018524 Approved Supported Mitochondria "Intracellular and membrane" Mitochondria "HPA018524: AB_1854355" "unprognostic (2.90e-1)" "unprognostic (1.41e-3)" "unprognostic (2.41e-1)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-1)" "unprognostic (7.75e-2)" "unprognostic (3.15e-1)" "unprognostic (1.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.81e-1)" "prognostic favourable (3.27e-8)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (9.45e-2)" 26.0 62.0 29.9 16.9 40.5 21.0 19.1 18.4 50.1 18.6 24.7 19.7 24.3 34.7 18.2 15.1 28.3 19.0 22.7 82.4 26.5 27.5 50.3 47.6 16.3 19.1 28.3 22.4 20.8 41.3 25.4 26.7 18.0 25.9 22.9 18.3 30.1 41.3 32.2 156.6 17.3 26.7 19.8 18.2 20.3 25.0 21.1 15.7 29.6 29.2 53.9 24.2 19.1 14.8 37.3 66.6 23.6 46.1 59.0 39.6 42.6 26.8 66.7 18.5 25.1 13.8 12.4 24.3 19.1 16.6 29.6 23.0 62.1 28.7 20.8 34.8 16.5 33.2 21.2 23.2 10.6 24.8 48.8 18.9 42.5 32.6 33.0 17.7 20.9 15.6 24.1 21.7 24.9 19.8 19.4 22.6 19.3 63.7 38.9 37.9 22.7 56.6 27.1 17.9 67.3 37.2 21.8 23.2 18.9 13.9 32.2 67.5 44.2 19.4 15.3 28.7 25.3 41.6 26.3 30.9 32.5 17.6 46.2 21.3 20.0 15.8 46.1 23.6 39.6 45.1 37.0 37.3 34.2 36.0 63.3 30.2 33.0 36.7 4.4 59.0 24.9 66.6 39.6 42.6 29.9 40.5 18.4 50.1 26.5 27.5 28.3 22.4 25.9 15.7 NDUFV1 CI-51K ENSG00000167792 "NADH:ubiquinone oxidoreductase core subunit V1" P49821 11 67606852-67612535 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease mutation, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 150.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045211, HPA075051" Approved Supported Mitochondria,Cytosol Mitochondria Cytosol "HPA045211: AB_10962830, HPA075051: " "unprognostic (4.57e-2)" "unprognostic (2.17e-2)" "unprognostic (2.84e-1)" "unprognostic (7.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.54e-3)" "unprognostic (1.19e-1)" "unprognostic (3.31e-2)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "unprognostic (4.02e-2)" "unprognostic (3.03e-2)" "prognostic favourable (7.49e-10)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" 23.3 28.9 27.3 20.7 33.9 20.3 18.9 32.9 48.8 18.5 33.0 23.1 19.2 40.6 19.4 21.5 25.5 22.5 23.4 93.0 26.5 24.1 39.0 41.5 15.9 20.6 31.5 40.5 24.6 38.3 49.2 18.8 15.7 34.8 16.1 25.1 17.6 27.3 27.0 150.8 28.4 30.3 22.7 23.1 21.5 28.2 30.2 24.3 18.3 23.4 67.9 20.3 18.7 18.6 23.8 41.2 13.5 30.7 36.2 28.2 24.3 26.2 28.2 14.4 28.8 18.0 18.1 26.9 16.4 15.8 25.7 17.2 53.3 31.8 48.5 34.6 14.1 35.4 30.3 25.6 8.1 24.6 23.9 19.9 38.3 26.3 25.5 27.0 22.2 26.8 24.8 20.9 18.7 22.7 36.1 39.7 15.6 39.4 31.5 53.5 14.1 35.5 36.6 27.9 78.7 20.8 19.7 22.9 21.6 20.7 72.5 54.7 36.8 27.5 18.0 24.9 18.6 35.4 17.2 38.8 22.1 24.2 29.0 28.6 23.9 12.6 26.7 13.5 25.9 30.7 28.2 23.2 21.7 24.5 41.2 23.8 20.2 25.1 4.8 36.2 17.4 26.5 27.8 24.3 27.3 33.9 32.9 48.8 26.5 24.1 31.5 40.5 34.8 24.3 NDUFV2 CI-24k ENSG00000178127 "NADH:ubiquinone oxidoreductase core subunit V2" P19404 18 9102630-9134345 "Enzymes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003404, HPA077896" Supported Supported Mitochondria Mitochondria "HPA003404: AB_1079466, HPA077896: " "unprognostic (1.18e-1)" "unprognostic (3.89e-2)" "unprognostic (2.89e-1)" "unprognostic (8.22e-2)" "unprognostic (1.32e-2)" "unprognostic (6.72e-3)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "unprognostic (6.72e-3)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (1.31e-1)" "unprognostic (6.56e-2)" "unprognostic (1.95e-3)" 20.0 34.5 25.2 18.0 23.7 31.1 25.6 20.6 37.3 15.6 26.1 13.1 20.3 23.1 14.7 21.5 27.5 13.9 17.6 82.6 22.7 23.8 40.7 89.1 17.2 29.9 26.7 19.4 11.2 36.3 14.9 14.9 21.6 26.2 20.8 27.8 17.8 20.1 20.2 122.6 17.4 24.4 23.5 20.8 19.3 25.2 19.0 12.7 20.5 20.5 59.5 22.7 20.4 14.1 55.6 74.7 49.3 45.1 27.0 53.5 48.1 19.6 20.7 23.9 22.2 17.8 25.3 20.3 24.8 39.5 32.9 31.2 38.6 16.3 30.4 22.8 23.3 10.0 23.2 25.8 31.5 15.3 20.5 19.4 21.3 52.1 20.5 54.0 24.2 21.3 21.6 20.2 22.0 35.4 30.9 96.1 30.1 24.7 37.7 47.4 20.0 25.8 18.0 17.7 115.3 52.4 32.0 25.2 18.7 24.5 28.0 31.2 26.2 41.2 21.6 41.9 29.8 30.0 32.2 27.8 41.2 34.1 29.8 24.0 27.0 49.3 39.9 44.1 30.2 45.1 37.6 55.6 45.5 35.7 56.6 43.6 40.0 36.9 18.0 27.0 41.6 74.7 53.5 48.1 25.2 23.7 20.6 37.3 22.7 23.8 26.7 19.4 26.2 12.7 NEDD4 "KIAA0093, MGC176705, NEDD4-1, RPF1" ENSG00000069869 "Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase" P46934 15 55826922-55993746 "Enzymes, Predicted intracellular proteins, Transporters" "Host-virus interaction, Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 57.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001991, HPA039883, CAB072833" Approved Approved Cytosol Cytosol "CAB001991: , CAB072833: , HPA039883: AB_10795683" "unprognostic (1.18e-1)" "unprognostic (2.10e-2)" "unprognostic (5.66e-3)" "unprognostic (1.15e-1)" "unprognostic (6.97e-2)" "unprognostic (2.23e-1)" "unprognostic (3.18e-3)" "prognostic unfavourable (5.14e-4)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (4.96e-2)" "unprognostic (1.43e-2)" "prognostic unfavourable (3.74e-6)" "unprognostic (6.38e-3)" "unprognostic (2.98e-1)" "unprognostic (2.22e-1)" "unprognostic (2.35e-2)" 14.1 4.1 2.5 3.1 3.3 4.5 8.7 1.5 2.7 9.9 9.4 2.8 3.4 3.4 10.1 4.1 8.2 3.8 4.5 4.1 2.9 2.4 8.6 21.5 7.2 2.1 3.5 1.3 6.6 2.8 6.5 6.7 20.1 3.5 8.4 3.4 5.4 4.0 6.4 57.7 7.1 15.2 10.9 6.0 5.9 4.4 2.6 3.1 9.4 5.7 9.0 3.3 11.9 8.9 0.1 1.6 1.2 2.8 1.2 2.9 0.9 7.3 11.4 3.1 3.0 4.1 6.8 5.1 14.1 22.3 10.4 10.5 5.1 2.2 1.8 3.7 5.3 12.2 3.4 9.3 17.1 4.1 2.1 9.1 2.7 2.6 21.9 4.0 0.9 11.5 23.0 12.5 21.1 8.5 3.9 0.0 30.5 3.8 5.3 0.0 0.8 1.7 3.9 24.7 1.0 4.3 14.6 0.3 2.0 6.3 4.5 5.6 5.6 3.0 29.6 23.2 7.7 4.9 22.9 1.2 2.6 4.8 15.7 8.5 5.5 0.6 1.0 0.0 1.3 2.8 2.9 0.1 1.5 1.2 0.8 0.0 1.4 1.6 1.2 1.2 1.9 1.6 1.3 0.9 2.5 3.3 1.5 2.7 2.9 2.4 3.5 1.3 3.5 3.1 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase" Q96PU5 18 58044367-58401540 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 50.1;SK-MEL-30: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 4 "granulocytes: 4.7;T-cells: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favourable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 5.9 6.8 9.1 5.4 38.8 13.2 15.8 21.4 24.7 5.0 22.6 3.2 18.2 11.1 3.6 6.1 7.0 6.0 7.6 12.7 9.8 7.1 29.9 10.1 26.9 2.5 7.2 14.9 3.0 33.2 9.2 16.5 13.0 4.1 30.6 25.2 12.2 16.5 23.2 38.3 5.9 26.8 8.2 3.2 3.1 26.0 4.6 8.8 0.8 9.1 5.5 5.1 14.9 9.3 1.4 0.4 4.7 0.7 0.9 8.1 0.5 18.4 6.6 3.9 5.8 1.4 0.5 13.6 5.2 23.7 13.4 20.5 7.7 10.0 3.9 16.1 2.0 13.4 5.2 23.1 27.7 9.2 4.6 2.8 4.1 50.1 0.7 0.1 1.7 3.5 15.1 18.1 22.0 1.0 4.8 1.7 5.5 4.5 0.2 0.2 3.4 10.2 3.8 5.3 4.5 13.3 24.1 4.9 1.3 4.3 1.3 39.1 7.9 1.6 7.9 36.2 10.9 2.0 22.3 2.3 3.9 2.4 7.4 2.8 2.9 4.7 0.6 1.7 0.4 0.7 1.0 1.4 1.3 0.3 0.3 0.6 0.8 0.6 0.3 0.9 0.1 0.4 8.1 0.5 9.1 38.8 21.4 24.7 9.8 7.1 7.2 14.9 4.1 8.8 NEIL1 "FLJ22402, FPG1, hFPG1, NEI1" ENSG00000140398 "Nei like DNA glycosylase 1" Q96FI4 15 75346955-75357114 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 11.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 4.7;memory B-cell: 4.0;naive B-cell: 6.5;NK-cell: 14.1" "Group enriched" "Detected in many" 12 "B-cells: 6.5;NK-cells: 14.1;T-cells: 4.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054084 Approved Supported Nucleoplasm Nucleoplasm "HPA054084: " "unprognostic (9.84e-3)" "unprognostic (1.19e-1)" "unprognostic (1.15e-2)" "unprognostic (4.62e-3)" "unprognostic (3.21e-2)" "unprognostic (1.81e-2)" "unprognostic (2.24e-2)" "unprognostic (1.17e-3)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "prognostic favourable (2.09e-4)" "unprognostic (3.50e-3)" "unprognostic (8.60e-2)" "unprognostic (9.24e-2)" "unprognostic (2.05e-1)" "unprognostic (3.03e-1)" "unprognostic (2.27e-3)" 7.1 14.8 12.9 28.2 14.5 6.8 9.3 24.4 15.4 10.8 8.3 4.9 23.2 10.1 8.4 11.6 6.4 10.0 10.2 5.3 12.8 5.7 7.9 9.1 9.3 9.8 6.0 9.8 11.0 10.8 9.1 9.0 4.6 8.0 10.4 2.4 7.1 25.0 24.2 13.6 11.7 9.5 4.3 5.9 6.8 9.9 3.8 7.0 15.4 8.2 5.2 13.3 7.5 8.5 6.5 0.2 0.7 0.5 14.1 4.7 1.0 2.1 3.6 2.4 1.5 0.7 0.8 4.5 1.3 0.0 0.5 0.1 0.6 4.0 11.4 2.1 0.2 6.3 1.4 0.4 0.0 5.6 9.3 1.9 9.9 1.8 0.9 2.2 2.7 0.3 1.8 0.6 0.0 1.4 1.2 3.4 0.4 2.9 0.4 6.2 2.1 0.8 2.1 1.4 0.5 2.1 2.4 1.4 2.8 2.2 1.0 3.1 4.2 3.3 6.2 1.3 2.5 1.9 1.1 5.3 5.2 9.3 1.2 9.3 1.2 0.0 0.5 0.0 4.7 0.1 1.3 4.0 0.8 1.0 0.2 6.5 1.4 1.4 0.7 14.1 0.1 0.2 0.2 1.0 12.9 14.5 24.4 15.4 12.8 5.7 6.0 9.8 8.0 7.0 NEIL2 "FLJ31644, MGC2832, MGC4505, NEH2" ENSG00000154328 "Nei like DNA glycosylase 2" Q969S2 8 11769639-11787346 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA073029, HPA073916" Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA073029: , HPA073916: " "unprognostic (1.52e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (9.88e-2)" "unprognostic (2.18e-2)" "unprognostic (5.72e-2)" "unprognostic (2.70e-1)" "unprognostic (2.88e-2)" "unprognostic (5.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.99e-3)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (5.29e-2)" "unprognostic (1.91e-1)" "unprognostic (2.09e-1)" "unprognostic (4.05e-1)" 10.2 21.8 18.7 6.8 17.7 2.7 10.3 11.8 20.9 11.3 5.6 9.0 7.0 3.6 9.9 15.4 6.5 17.9 6.9 14.2 15.4 20.0 9.3 11.0 7.7 8.4 18.4 16.1 12.6 10.9 7.8 13.2 7.6 20.3 10.5 6.1 9.7 11.5 10.3 24.7 18.1 4.6 10.2 12.3 9.5 5.1 26.8 13.3 1.8 15.5 7.1 7.9 7.4 15.8 14.7 5.5 0.8 2.5 9.1 13.6 4.7 5.1 14.5 9.1 17.7 4.4 8.1 4.1 8.2 6.8 8.0 5.5 4.4 5.6 2.0 3.2 9.8 4.5 8.6 9.0 11.0 6.0 4.3 7.1 3.4 8.6 3.5 3.0 5.3 7.2 13.3 6.9 6.4 7.4 9.9 6.9 9.4 5.4 0.5 3.2 8.1 7.8 8.9 11.7 5.5 9.2 7.7 14.0 11.1 6.4 3.4 11.6 5.4 0.5 9.1 9.1 13.1 2.4 11.4 6.5 13.5 3.6 23.9 10.5 18.4 0.4 1.5 0.1 9.1 2.5 12.1 14.7 9.3 10.8 3.0 11.4 13.6 12.0 0.8 9.1 1.1 5.5 5.8 4.7 18.7 17.7 11.8 19.8 15.4 20.0 18.4 16.1 20.3 13.3 NEIL3 "FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3" ENSG00000109674 "Nei like DNA glycosylase 3" Q8TAT5 4 177309836-177362943 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 70.8" "Cell line enhanced" "Detected in many" "HDLM-2: 26.5;HL-60: 28.8;Karpas-707: 37.9;MOLT-4: 29.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065761 Enhanced Nucleoplasm Nucleoplasm "HPA065761: " "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (1.42e-1)" "prognostic unfavourable (5.45e-4)" "unprognostic (4.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.64e-7)" "prognostic unfavourable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (6.51e-4)" "unprognostic (2.82e-3)" "unprognostic (0.00e+0)" "unprognostic (3.25e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-2)" 0.5 0.4 0.2 7.4 0.2 9.3 0.7 0.1 0.2 0.8 1.5 0.1 0.1 1.5 0.5 0.1 5.6 0.2 0.3 0.5 0.2 0.2 0.4 0.4 0.9 5.1 0.2 0.1 0.3 0.2 0.0 0.2 1.6 0.2 0.2 2.1 0.2 0.8 0.1 0.2 3.4 1.7 0.5 0.7 1.5 0.8 3.5 0.3 70.8 0.2 1.1 5.0 0.7 1.3 0.2 0.3 0.8 0.0 1.6 1.6 0.2 7.0 5.9 6.3 3.1 0.7 1.3 3.1 8.8 3.2 9.8 5.8 2.1 6.2 7.8 1.3 2.3 3.3 6.6 3.5 14.2 26.5 4.3 5.4 4.6 5.6 0.2 28.8 3.7 0.1 0.2 10.1 2.2 3.7 5.5 37.9 6.3 3.1 29.2 11.1 2.9 4.3 5.9 4.3 2.5 2.5 0.9 4.9 3.4 4.4 5.1 2.4 4.1 7.5 1.7 5.9 4.6 3.0 8.8 2.6 1.7 12.4 3.9 10.3 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.0 0.2 0.0 1.1 0.8 1.6 0.0 0.3 1.6 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.3 NEK1 "KIAA1901, NY-REN-55" ENSG00000137601 "NIMA related kinase 1" Q96PY6 4 169392857-169612629 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Ciliopathy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020873, HPA040413" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" Cytosol "Nucleoplasm, Centriolar satellite" "HPA020873: AB_10671583, HPA040413: AB_10671169" "unprognostic (4.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "unprognostic (6.98e-2)" "unprognostic (3.10e-1)" "unprognostic (3.95e-1)" "unprognostic (3.29e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (4.06e-3)" "unprognostic (2.21e-1)" "prognostic favourable (1.42e-4)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.10e-2)" "unprognostic (3.46e-1)" 9.6 10.5 13.5 9.2 15.8 6.0 8.7 20.7 14.5 13.6 8.4 12.5 7.1 5.4 12.4 9.1 7.9 15.7 10.2 11.4 13.7 13.2 10.2 6.9 7.7 8.0 15.9 11.3 16.3 6.6 15.3 16.5 7.2 16.0 11.6 7.7 8.9 6.4 10.6 7.1 4.7 5.7 11.1 18.2 8.0 8.1 18.3 14.8 14.7 13.3 6.4 7.4 10.0 8.2 4.5 3.3 6.7 3.3 2.2 5.3 1.3 4.2 1.9 7.8 8.4 12.1 13.6 2.5 9.0 8.1 7.2 6.9 2.4 5.1 11.3 1.7 7.8 1.4 7.3 7.6 8.2 12.4 5.0 7.6 7.8 2.9 7.2 7.7 6.1 10.8 4.4 7.3 12.9 7.0 13.5 21.6 9.2 2.7 9.9 3.4 2.5 4.5 6.1 5.1 3.6 7.6 5.0 8.5 9.7 6.5 3.2 6.0 4.0 3.4 8.4 4.6 4.2 4.8 6.0 8.7 13.4 8.7 7.6 3.8 8.0 6.7 2.1 1.8 4.4 3.3 4.8 4.4 3.4 2.7 1.5 4.5 5.1 5.3 1.1 2.2 1.6 3.3 3.2 1.3 13.5 15.8 20.7 12.9 13.7 13.2 15.9 11.3 16.0 14.8 NEK10 FLJ32685 ENSG00000163491 "NIMA related kinase 10" Q6ZWH5 3 27110085-27369460 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 31.4" "Cell line enhanced" "Detected in many" "BJ: 7.6;LHCN-M2: 10.5;U-2 OS: 8.9" "Cancer enriched" "Detected in single" 5 "breast cancer: 1.8" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038941 Uncertain Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA038941: AB_10673600" "prognostic favourable (4.20e-4)" "unprognostic (2.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.15e-2)" "unprognostic (3.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-2)" "unprognostic (2.20e-3)" "unprognostic (1.37e-1)" "unprognostic (7.67e-2)" "unprognostic (1.33e-2)" "unprognostic (1.38e-2)" "unprognostic (1.57e-3)" "unprognostic (2.14e-1)" 0.4 0.5 4.5 0.5 14.6 0.4 14.2 0.6 6.8 1.6 2.0 1.1 2.0 2.5 0.9 8.3 2.0 10.5 2.1 3.1 8.4 3.8 1.4 2.5 4.5 0.6 0.8 6.7 2.7 0.8 0.5 9.0 0.3 3.4 1.9 0.7 1.3 0.5 1.4 10.5 0.4 1.0 1.2 0.8 0.6 1.1 31.4 1.3 0.3 0.8 0.3 0.7 1.4 0.4 0.4 0.2 1.9 0.1 0.1 0.6 0.1 1.0 2.0 1.0 1.2 0.9 2.0 0.4 7.6 1.2 2.1 1.9 0.0 0.5 0.7 1.9 3.2 0.1 0.5 0.5 2.3 1.4 0.8 0.2 4.1 3.7 0.2 0.4 1.0 2.4 0.5 3.2 0.1 1.4 0.1 0.7 10.5 0.1 0.8 0.5 0.7 0.3 1.0 0.4 0.3 4.0 0.6 0.2 0.2 1.2 0.4 0.6 6.1 0.4 0.9 5.6 8.9 0.3 0.7 0.3 0.2 0.5 4.8 0.8 2.1 0.1 0.1 0.2 0.6 0.1 0.1 0.1 0.5 0.4 0.0 0.4 0.1 0.5 1.9 0.1 0.0 0.2 0.0 0.1 4.5 14.6 0.6 6.8 8.4 3.8 0.8 6.7 3.4 1.3 NEK11 FLJ23495 ENSG00000114670 "NIMA related kinase 11" Q8NG66 3 131026850-131350465 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016908 Approved Supported Nucleoplasm Nucleoplasm "HPA016908: AB_1854364" "unprognostic (9.15e-3)" "prognostic favourable (7.10e-4)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (4.85e-3)" "unprognostic (2.48e-5)" "unprognostic (5.38e-2)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "prognostic favourable (5.92e-6)" "unprognostic (2.46e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" 3.9 5.8 9.3 2.7 11.1 0.5 8.7 2.7 7.6 7.3 2.8 11.2 8.4 2.0 6.5 16.0 3.2 26.9 6.0 2.9 9.1 10.0 8.2 1.1 5.5 1.7 7.8 5.4 8.7 2.8 5.0 9.3 4.6 17.3 4.0 3.3 3.0 3.8 6.7 1.7 2.8 2.6 4.3 7.3 1.8 2.3 17.8 5.5 0.2 12.3 2.5 1.7 4.2 3.0 0.9 1.0 1.1 1.3 0.3 2.9 0.3 5.8 2.4 1.7 5.1 6.9 10.4 1.0 2.9 5.4 4.4 3.4 2.2 8.2 0.3 2.1 5.1 3.2 0.5 5.0 6.2 0.5 0.7 0.8 0.4 1.0 2.3 0.6 1.5 4.3 8.4 4.7 2.1 0.9 0.2 0.9 7.4 4.1 0.1 0.5 0.5 2.3 0.0 0.2 0.1 10.1 2.3 2.2 2.4 1.4 0.1 1.9 4.8 0.1 0.9 4.6 2.2 3.6 1.3 1.3 2.3 0.1 3.2 0.2 0.8 0.0 0.3 1.1 0.6 1.3 1.2 0.9 2.9 2.6 0.5 0.6 1.0 0.8 0.9 0.3 0.9 1.0 1.5 0.3 9.3 11.1 2.7 7.6 9.1 10.0 7.8 5.4 17.3 5.5 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.0;testis: 41.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 3.2" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: " "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavourable (9.47e-6)" "prognostic unfavourable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 1.1 0.7 0.6 6.7 0.5 7.4 1.3 0.3 0.9 0.9 2.5 0.3 0.3 3.4 0.3 1.2 4.2 0.7 1.4 0.9 1.0 0.3 0.6 0.6 1.0 3.9 0.3 0.3 0.6 0.3 0.0 0.3 1.2 0.4 0.9 3.6 0.4 1.0 0.3 0.3 1.8 3.0 0.6 0.6 1.6 1.1 41.0 0.4 14.0 0.3 1.5 4.8 0.6 1.6 1.8 0.9 2.7 0.5 3.9 4.3 0.9 30.3 21.9 16.8 12.0 1.0 1.7 18.5 11.7 11.0 20.7 17.8 11.7 29.8 16.1 5.7 9.0 16.3 14.5 8.8 26.1 24.6 12.1 7.7 19.1 15.7 0.1 15.2 10.5 0.5 1.0 15.9 17.2 13.2 21.1 28.4 20.7 8.4 16.5 10.3 15.9 11.2 16.4 25.7 24.5 7.2 8.7 15.2 16.9 16.9 19.0 14.7 29.2 9.1 6.9 10.3 20.5 20.3 31.4 11.8 21.7 21.3 9.0 11.7 17.1 2.7 0.5 0.4 0.5 0.3 0.2 1.5 0.6 0.3 0.1 1.8 1.1 0.7 2.4 3.9 0.4 0.9 4.3 0.9 0.6 0.5 0.3 0.9 1.0 0.3 0.3 0.3 0.4 0.4 NEK3 "HSPK36, MGC29949" ENSG00000136098 "NIMA related kinase 3" P51956 13 52132639-52159861 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019062, HPA043230" Enhanced Approved Microtubules Microtubules "HPA019062: , HPA043230: " "unprognostic (8.97e-2)" "unprognostic (2.54e-2)" "unprognostic (8.12e-2)" "unprognostic (1.84e-1)" "unprognostic (2.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (4.30e-3)" "unprognostic (1.16e-3)" "unprognostic (1.70e-2)" "unprognostic (1.17e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (4.15e-2)" "unprognostic (5.34e-2)" 7.7 2.8 7.1 5.4 12.9 7.1 7.3 3.2 7.1 7.0 13.8 20.4 3.1 7.8 9.1 5.8 3.9 6.0 6.4 5.0 8.7 5.2 6.1 5.7 7.2 4.2 14.0 9.5 7.9 6.4 2.2 3.7 14.8 11.3 5.4 15.0 6.8 5.2 5.0 4.1 5.4 11.7 7.3 9.6 3.9 4.6 14.7 13.3 2.4 5.0 2.7 4.3 6.5 6.0 4.4 7.8 5.9 7.7 2.0 3.5 1.6 0.2 1.4 13.1 7.5 4.2 6.6 0.2 4.2 4.3 5.1 5.7 5.0 7.3 0.0 0.2 5.2 0.9 0.2 3.2 3.1 8.7 6.9 1.0 1.4 13.6 5.4 12.6 6.8 4.8 5.8 2.6 12.2 7.7 1.8 4.4 5.2 3.6 0.6 15.2 12.9 0.3 0.3 1.1 4.7 7.3 1.3 1.3 9.1 1.9 4.0 8.8 1.7 16.2 6.6 0.7 4.3 4.0 4.5 4.7 1.6 8.8 1.1 5.0 7.1 5.9 7.7 5.3 2.1 6.6 1.3 4.4 2.5 1.3 7.8 2.5 1.7 0.6 0.5 2.0 1.5 6.9 3.5 1.6 7.1 12.9 3.2 7.1 8.7 5.2 14.0 9.5 11.3 13.3 NEK4 "NRK2, pp12301, STK2" ENSG00000114904 "NIMA related kinase 4" P51957 3 52708449-52770949 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015750, HPA058543" Enhanced Supported Cytosol Cytosol "HPA015750: AB_1854367, HPA058543: " "unprognostic (1.32e-1)" "unprognostic (1.57e-1)" "prognostic favourable (2.69e-5)" "unprognostic (9.65e-3)" "unprognostic (3.42e-1)" "unprognostic (6.64e-2)" "unprognostic (8.75e-3)" "unprognostic (2.27e-1)" "unprognostic (7.85e-2)" "unprognostic (5.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (3.74e-3)" "unprognostic (5.11e-2)" "unprognostic (2.85e-1)" "unprognostic (1.51e-2)" "unprognostic (8.39e-2)" 7.2 10.7 15.5 9.1 15.7 7.3 11.0 20.2 16.1 10.6 8.4 10.6 9.6 7.6 10.3 10.7 8.1 15.8 7.5 7.4 12.5 14.2 11.6 12.4 7.7 8.8 12.7 8.6 15.8 10.2 13.4 17.6 8.7 11.9 9.4 9.7 9.1 8.5 11.3 10.8 5.3 6.6 9.5 10.7 7.9 11.0 47.7 12.4 11.1 15.5 5.0 10.4 9.3 10.7 5.1 6.4 12.4 11.8 4.6 5.2 5.5 12.8 10.0 13.7 10.8 12.6 9.1 14.9 9.1 12.3 17.1 17.3 8.7 9.6 13.2 4.3 8.9 6.0 16.7 10.7 23.0 13.1 7.0 10.3 12.2 11.1 7.8 25.1 10.4 5.6 9.9 21.9 14.6 6.4 12.8 10.7 10.7 10.9 13.5 9.2 11.9 9.9 11.9 12.0 9.7 9.6 18.5 10.1 6.1 19.1 11.8 9.0 11.0 15.2 5.8 11.5 11.7 18.3 16.8 12.0 17.5 13.0 13.1 11.9 12.4 12.4 11.8 5.8 4.6 7.3 5.2 3.6 4.0 4.8 6.4 5.1 4.9 4.2 1.8 4.6 4.8 3.2 3.1 5.5 15.5 15.7 20.2 16.1 12.5 14.2 12.7 8.6 11.9 12.4 NEK5 ENSG00000197168 "NIMA related kinase 5" Q6P3R8 13 52033611-52129078 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 11.8;fallopian tube: 12.7;testis: 15.7" "Cell line enhanced" "Detected in some" "T-47d: 4.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035565, HPA041399" Enhanced "HPA035565: AB_10672095, HPA041399: " "unprognostic (4.14e-2)" "unprognostic (1.49e-1)" "unprognostic (1.89e-1)" "unprognostic (5.80e-3)" "unprognostic (2.80e-2)" "unprognostic (2.47e-1)" "unprognostic (3.57e-2)" "unprognostic (6.50e-2)" "unprognostic (8.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.94e-1)" "unprognostic (2.06e-3)" "unprognostic (1.83e-3)" "unprognostic (1.10e-1)" "unprognostic (1.19e-3)" "unprognostic (9.44e-3)" 0.6 0.3 3.2 1.4 3.2 0.7 0.9 0.4 2.6 0.9 0.4 5.4 0.3 0.5 2.5 3.0 0.4 12.7 0.5 1.3 3.2 1.6 0.9 0.3 4.9 0.5 0.7 1.3 2.8 0.5 0.9 5.3 0.8 11.8 1.5 0.4 0.3 0.5 0.3 0.6 0.5 0.4 0.5 0.9 0.4 0.3 15.7 2.1 0.0 0.7 0.0 0.3 0.4 0.4 0.9 1.1 2.5 0.5 0.6 0.4 0.0 0.5 0.6 0.4 2.2 0.3 1.4 2.8 0.0 0.0 0.0 0.3 0.2 1.4 0.7 0.2 0.0 0.5 0.3 0.5 0.1 0.2 0.4 0.8 0.8 0.5 0.4 1.4 1.7 0.4 1.1 0.2 0.8 0.3 1.5 1.0 0.0 1.7 0.7 1.1 0.6 0.8 0.3 0.2 0.0 2.4 0.6 0.8 1.1 0.5 0.0 1.2 4.2 1.7 0.6 0.2 0.3 0.2 0.3 0.4 0.2 0.4 0.1 0.3 0.4 2.5 0.5 0.1 0.3 0.3 0.4 0.5 0.2 0.2 0.1 0.9 0.3 0.3 0.9 0.6 0.1 1.1 0.2 0.0 3.2 3.2 0.4 2.6 3.2 1.6 0.7 1.3 11.8 2.1 NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" "Nucleoplasm, Centriolar satellite, Cytosol" "CAB045993: AB_2150651, HPA056828: " "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavourable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" 14.8 5.3 26.1 22.2 29.1 12.8 18.8 7.2 21.2 20.5 15.6 13.4 4.3 12.5 9.2 7.5 6.8 8.5 18.4 7.0 17.1 16.6 12.9 51.9 17.0 18.1 19.4 13.3 11.2 20.5 1.6 6.4 21.4 14.7 14.8 16.6 18.5 16.9 13.2 5.5 5.1 18.2 23.4 13.0 11.3 19.0 5.8 12.9 4.0 6.3 1.9 22.0 17.7 10.1 21.9 11.5 29.0 18.8 8.3 3.8 7.6 7.7 12.7 12.3 4.8 23.4 30.4 15.3 9.7 15.6 15.1 12.6 12.1 14.5 9.4 15.6 18.8 1.5 6.3 28.3 10.3 10.3 5.6 25.9 10.7 21.1 27.9 4.6 65.0 40.6 4.6 14.3 14.9 16.4 4.6 0.4 27.0 8.1 0.2 5.1 3.1 11.6 10.0 9.2 4.8 16.2 2.8 5.5 1.9 3.2 6.1 13.8 13.1 19.1 32.1 11.1 11.2 7.6 6.6 2.1 2.6 5.4 13.9 10.6 14.7 10.2 18.8 29.0 3.8 12.3 2.4 21.9 2.3 3.2 11.5 9.0 0.4 1.6 23.4 8.3 14.7 10.6 2.8 7.6 26.1 29.1 7.2 21.2 17.1 16.6 19.4 13.3 14.7 12.9 NEK7 ENSG00000151414 "NIMA related kinase 7" Q8TDX7 1 198156963-198322420 "Enzymes, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 83.7;fHDF/TERT166: 113.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015520, HPA018193" Approved Supported Nucleoplasm Nucleoplasm "HPA015520: AB_1854371, HPA018193: AB_1854372" "unprognostic (2.08e-1)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (5.38e-2)" "unprognostic (4.26e-2)" "unprognostic (3.00e-2)" "unprognostic (2.14e-2)" "unprognostic (5.47e-2)" "unprognostic (4.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.46e-3)" "unprognostic (2.82e-1)" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-2)" "unprognostic (1.56e-1)" 31.7 31.4 24.9 15.2 23.0 5.6 23.7 7.8 15.6 19.3 20.6 25.5 13.7 11.3 24.5 11.4 18.7 12.8 15.1 74.7 23.9 20.4 16.1 16.0 22.3 14.9 26.8 13.4 17.2 11.1 14.6 17.6 40.5 18.0 20.0 13.2 11.8 13.5 21.3 29.9 10.6 15.8 30.9 34.9 16.4 11.7 9.5 22.6 18.0 14.9 12.8 12.5 27.4 20.7 1.6 2.1 6.1 2.2 3.8 14.7 1.4 7.0 1.8 2.2 0.9 5.9 6.8 2.6 83.7 35.0 34.1 16.2 3.4 7.0 2.5 6.0 113.0 4.3 3.4 4.5 34.5 7.9 4.9 3.4 8.0 1.4 7.1 5.8 7.1 4.2 3.9 22.4 6.7 6.4 2.7 6.3 15.6 2.2 5.0 3.4 1.2 1.4 2.6 5.6 4.4 5.8 3.6 1.4 2.6 13.9 8.0 9.3 5.9 5.3 14.2 9.6 8.1 27.4 8.7 4.4 4.0 1.7 4.2 5.3 7.4 1.9 2.2 3.0 3.2 1.9 14.7 1.3 3.6 4.6 2.1 1.6 2.9 3.6 6.1 3.8 1.7 1.4 6.0 1.4 24.9 23.0 7.8 15.6 23.9 20.4 26.8 13.4 18.0 22.6 NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease mutation, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 14.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040661, HPA040679" Approved "HPA040661: AB_10794065, HPA040679: AB_10796226" "unprognostic (2.63e-1)" "unprognostic (4.57e-2)" "prognostic unfavourable (6.98e-4)" "unprognostic (6.25e-2)" "unprognostic (2.23e-2)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "prognostic favourable (4.52e-4)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-3)" "unprognostic (4.61e-2)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" 3.5 4.6 2.9 11.9 4.5 2.0 4.3 1.7 4.9 5.3 4.0 4.7 1.4 4.2 2.1 5.0 4.8 5.9 4.4 1.6 2.9 1.9 10.4 6.9 5.7 7.8 2.3 2.1 4.4 6.4 8.5 9.7 8.7 5.6 5.6 3.2 5.2 5.3 4.1 0.9 4.4 6.5 1.7 3.0 8.4 4.9 4.9 1.4 4.8 10.7 3.5 15.6 4.5 3.0 4.7 14.7 3.2 1.0 1.3 1.1 0.8 2.1 3.5 3.7 2.9 2.0 2.2 11.4 1.0 2.2 1.4 1.8 5.4 5.1 13.2 3.7 2.8 3.9 5.4 4.9 1.4 3.5 6.6 2.9 5.6 10.0 3.5 1.8 3.9 5.1 1.9 2.6 6.1 0.9 4.3 1.3 1.5 4.7 1.8 3.4 3.4 1.1 4.9 2.4 5.8 7.3 5.8 6.7 1.6 3.1 6.5 1.6 9.7 2.4 0.9 1.3 2.4 1.7 1.0 1.5 1.7 8.9 2.1 1.6 3.2 3.2 0.9 1.2 0.8 0.4 0.9 3.0 0.7 0.7 0.1 4.7 0.8 1.1 0.5 1.3 1.0 14.7 0.5 0.8 2.9 4.5 1.7 4.9 2.9 1.9 2.3 2.1 5.6 1.4 NEK9 "DKFZp434D0935, MGC16714, Nek8, NERCC" ENSG00000119638 "NIMA related kinase 9" Q8TD19 14 75079353-75127344 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001405 Approved Approved Mitochondria 190000 Mitochondria "HPA001405: AB_1079467" "unprognostic (1.00e-1)" "unprognostic (5.37e-2)" "unprognostic (9.97e-3)" "unprognostic (2.64e-2)" "unprognostic (3.86e-1)" "unprognostic (2.77e-1)" "unprognostic (1.12e-1)" "unprognostic (5.60e-3)" "unprognostic (2.81e-1)" "unprognostic (1.15e-1)" "prognostic favourable (5.63e-4)" "unprognostic (8.58e-2)" "unprognostic (1.36e-2)" "unprognostic (4.54e-2)" "unprognostic (9.22e-2)" "unprognostic (2.61e-1)" "unprognostic (1.57e-2)" 17.0 20.4 12.7 17.7 17.4 7.3 15.1 15.4 13.3 18.6 18.7 18.3 23.5 14.0 25.0 13.8 15.6 20.0 15.9 23.5 11.4 8.7 14.0 13.3 12.9 16.2 20.2 10.6 25.6 15.7 24.7 23.6 14.3 13.0 15.3 8.1 15.4 12.4 18.9 36.2 10.6 15.3 24.7 14.5 14.7 14.8 16.6 18.2 21.5 17.0 14.1 14.4 23.6 18.7 6.0 6.4 7.5 5.4 5.5 6.2 3.1 10.1 12.0 15.2 16.9 19.5 26.8 17.3 16.5 11.6 8.1 7.9 10.1 8.9 17.4 0.1 11.3 14.0 11.6 6.4 9.0 14.2 6.7 8.5 12.0 7.3 12.8 5.1 11.4 18.3 7.6 8.4 6.4 10.1 9.6 11.3 9.7 1.1 10.8 5.2 9.0 6.1 17.5 19.4 9.0 6.1 12.4 7.3 18.7 13.3 6.4 12.7 15.8 14.8 15.2 12.3 5.2 14.3 6.4 18.3 19.5 17.6 9.0 8.7 8.3 7.5 5.4 5.8 4.2 5.0 5.9 2.8 4.8 3.9 6.4 6.0 6.2 5.9 5.5 5.5 3.5 1.8 2.6 3.1 12.7 17.4 15.4 13.3 11.4 8.7 20.2 10.6 13.0 18.2 NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862906 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" 86000 Vesicles "Cell Junctions" "HPA015634: AB_1854386, HPA021506: AB_1854385" "unprognostic (3.84e-2)" "unprognostic (7.47e-2)" "unprognostic (9.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-3)" "unprognostic (1.38e-3)" "unprognostic (8.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.21e-2)" "unprognostic (4.44e-3)" "unprognostic (1.27e-1)" "unprognostic (2.70e-2)" "unprognostic (6.22e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-3)" 10.5 30.2 8.6 9.4 11.1 5.2 10.5 15.5 14.6 13.4 14.1 7.4 16.1 14.1 9.8 13.9 9.0 8.3 16.1 9.8 8.0 9.5 29.7 24.2 16.1 7.2 9.4 6.6 12.7 20.6 13.6 16.5 19.8 10.3 15.1 9.1 14.7 18.1 13.8 10.0 9.1 23.5 9.8 4.7 13.4 12.7 6.5 10.0 5.8 22.7 7.0 9.6 13.6 9.5 4.2 7.7 15.2 13.4 3.0 5.1 7.4 2.9 3.0 3.0 6.9 10.1 3.8 5.9 2.7 9.3 8.1 11.8 17.4 3.3 1.0 7.0 3.6 1.7 6.3 2.5 3.1 2.5 4.2 1.5 1.8 20.3 18.1 1.9 8.5 6.3 4.7 9.7 5.0 7.2 3.2 7.2 4.1 5.3 1.6 2.9 2.3 2.4 2.1 1.6 10.4 13.3 6.5 2.3 1.3 3.0 4.0 7.1 7.7 8.7 3.0 5.3 3.1 7.4 4.8 8.9 14.2 2.1 3.9 4.8 3.7 6.4 13.4 8.7 5.1 10.3 4.2 3.9 3.9 4.1 7.7 4.2 4.0 3.9 15.2 3.0 9.2 4.3 4.8 7.4 8.6 11.1 15.5 14.6 8.0 9.5 9.4 6.6 10.3 10.0 NEU2 SIAL2 ENSG00000115488 "Neuraminidase 2" Q9Y3R4 2 233032672-233035057 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "skin 1: 6.1" "Group enriched" "Detected in some" 4 "A-431: 1.1;BEWO: 1.6;PC-3: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.2;hippocampal formation: 1.1" CAB022336 Uncertain 9000 "CAB022336: " "unprognostic (1.30e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NEU3 ENSG00000162139 "Neuraminidase 3" Q9UQ49 11 74988134-75018893 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 44.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038729, HPA070381" Approved Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA038729: , HPA070381: " "unprognostic (1.67e-1)" "unprognostic (2.10e-1)" "unprognostic (2.55e-2)" "unprognostic (1.13e-3)" "unprognostic (2.95e-2)" "unprognostic (5.42e-2)" "unprognostic (1.63e-1)" "unprognostic (5.11e-2)" "unprognostic (3.91e-3)" "unprognostic (8.50e-2)" "prognostic favourable (5.98e-4)" "unprognostic (3.57e-3)" "unprognostic (3.80e-2)" "unprognostic (3.79e-1)" "unprognostic (2.38e-1)" "unprognostic (3.73e-1)" "unprognostic (1.84e-1)" 5.4 13.4 3.7 10.5 6.9 17.0 5.4 7.9 9.1 4.0 3.9 3.0 4.1 3.6 5.4 4.8 3.9 4.4 3.6 5.9 4.0 4.5 4.3 6.7 8.7 9.0 3.8 6.6 7.2 7.3 15.1 11.2 3.1 4.2 9.7 5.4 5.6 4.8 4.6 19.1 6.7 4.7 4.0 3.5 5.5 5.1 44.6 3.0 19.0 6.8 3.5 7.5 4.5 3.1 3.2 3.8 5.8 6.4 1.2 4.2 2.2 4.6 4.0 3.4 6.6 2.6 2.5 3.8 4.5 2.9 5.2 4.0 13.7 3.9 13.3 4.6 3.6 4.3 8.3 5.8 7.9 7.0 4.4 11.0 7.5 5.6 2.9 17.2 10.6 3.0 4.9 5.2 8.1 3.7 17.7 10.0 5.9 5.0 16.9 8.9 4.2 5.4 14.9 9.0 11.7 6.4 4.9 6.3 4.0 6.9 4.6 20.3 9.9 4.5 5.6 6.5 6.5 4.3 4.5 8.3 8.0 26.7 1.9 8.9 5.5 2.1 6.4 5.8 4.1 3.7 3.0 2.8 3.2 3.9 3.8 3.2 3.5 4.2 3.3 1.2 4.6 2.7 2.3 2.2 3.7 6.9 7.9 9.1 4.0 4.5 3.8 6.6 4.2 3.0 NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241808825-241817413 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 27.1;liver: 42.9" "Group enriched" "Detected in some" 21 "Hep G2: 22.0;HMC-1: 30.7" "Group enriched" "Detected in some" 7 "colorectal cancer: 2.3;glioma: 6.0;liver cancer: 6.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037394 Enhanced "HPA037394: " "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.85e-1)" "unprognostic (3.68e-4)" "unprognostic (3.76e-2)" "unprognostic (1.57e-1)" "unprognostic (8.70e-2)" "unprognostic (8.62e-2)" "unprognostic (1.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.92e-1)" "unprognostic (8.11e-4)" "unprognostic (2.00e-2)" "unprognostic (3.82e-1)" "unprognostic (6.64e-3)" "unprognostic (1.55e-2)" 0.6 0.5 6.5 0.7 5.3 5.7 0.3 1.9 7.0 0.6 13.9 4.9 0.0 9.3 0.3 0.3 0.7 1.1 2.6 0.6 6.4 5.8 1.4 42.9 0.4 0.5 6.9 4.4 0.4 0.3 0.3 0.4 0.4 3.8 0.5 6.1 0.0 0.4 0.4 3.6 0.3 27.1 0.4 4.1 0.5 0.5 0.6 2.3 0.0 0.4 2.8 0.3 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.5 5.3 1.9 4.0 6.4 5.8 6.9 4.4 3.8 2.3 NEURL1 "h-neu, neu-1, NEURL, RNF67" ENSG00000107954 "Neuralized E3 ubiquitin protein ligase 1" O76050 10 103493979-103592552 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Translation regulation, Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 37.1;skeletal muscle: 83.5" "Cell line enhanced" "Detected in some" "BEWO: 12.9;HeLa: 7.6;HMC-1: 6.5;SCLC-21H: 16.2;SiHa: 8.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "intermediate monocyte: 16.0;non-classical monocyte: 37.1" "Lineage enriched" "Detected in many" 17 "monocytes: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044204 Enhanced "HPA044204: AB_10959383" "unprognostic (1.21e-2)" "unprognostic (8.14e-2)" "unprognostic (1.18e-3)" "unprognostic (1.58e-4)" "unprognostic (1.31e-2)" "unprognostic (2.60e-1)" "unprognostic (5.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (4.31e-2)" "unprognostic (1.32e-3)" "unprognostic (1.08e-1)" "unprognostic (8.61e-3)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (2.91e-4)" "unprognostic (3.23e-1)" 1.1 3.9 18.5 3.0 17.5 2.0 1.0 28.2 27.2 6.1 8.6 0.6 1.2 7.7 13.2 11.0 3.6 2.1 2.0 1.1 12.0 7.6 1.3 1.1 1.3 1.3 4.5 18.9 2.1 12.8 2.9 6.5 13.3 6.1 2.8 7.3 7.8 1.5 1.7 83.5 1.9 11.7 11.7 1.2 2.0 4.4 7.5 2.1 0.0 1.2 8.5 1.1 9.2 1.7 0.4 2.1 1.0 37.1 0.2 0.4 1.2 0.8 0.2 1.3 0.0 0.4 0.1 12.9 0.5 0.8 0.2 0.1 0.3 0.3 0.4 0.7 0.1 0.7 0.4 0.2 0.1 0.3 0.7 0.2 7.6 0.6 0.0 0.3 6.5 0.2 0.5 0.1 0.6 0.0 2.1 0.4 0.2 1.1 1.3 0.8 0.0 3.9 0.2 0.6 1.4 0.0 0.5 16.2 5.5 8.1 0.0 0.4 0.7 1.5 0.0 0.1 0.9 0.2 0.2 0.9 0.2 0.3 0.5 0.0 0.3 0.2 1.0 0.2 0.3 16.0 0.4 0.4 0.4 0.4 2.1 0.3 0.4 0.3 1.0 0.2 37.1 1.7 0.1 1.2 18.5 17.5 28.2 27.2 12.0 7.6 4.5 18.9 6.1 2.1 NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641266-172691540 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 27.0;T-47d: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported Vesicles Vesicles "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavourable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" 26.6 11.8 7.5 10.3 3.2 1.5 23.9 0.6 7.0 21.4 17.5 5.6 31.2 5.7 26.7 24.7 14.0 15.8 23.0 19.2 10.7 4.2 7.6 4.4 10.5 7.8 3.1 3.2 20.9 4.8 4.1 6.0 5.1 2.7 20.7 11.6 6.1 4.9 28.4 12.3 14.7 12.1 29.1 1.5 0.6 5.9 6.6 2.8 3.6 7.2 13.9 5.4 16.0 30.8 0.0 0.6 0.0 0.2 0.0 0.2 0.0 4.4 2.3 1.2 5.6 0.4 0.2 0.1 5.0 2.2 2.7 3.9 8.5 2.0 0.0 1.4 3.2 1.3 0.5 2.2 1.8 8.1 0.3 6.1 8.1 0.0 0.4 0.0 1.9 0.0 9.7 0.6 2.7 0.4 0.0 1.9 5.7 4.9 1.4 0.1 0.8 0.2 27.0 6.0 0.8 0.1 1.0 1.0 5.8 4.8 7.6 0.2 12.7 0.9 0.8 2.0 11.9 1.4 3.1 0.8 0.2 0.0 5.8 0.1 1.7 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.5 3.2 0.6 7.0 10.7 4.2 3.1 3.2 2.7 2.8 NFS1 "IscS, NifS" ENSG00000244005 "NFS1, cysteine desulfurase" Q9Y697 20 35668055-35699359 "Enzymes, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB034314, HPA051801, HPA054755" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB034314: AB_2235980, HPA051801: AB_2681616, HPA054755: AB_2682594" "unprognostic (1.72e-1)" "unprognostic (2.96e-1)" "unprognostic (1.27e-2)" "unprognostic (5.88e-3)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "unprognostic (1.14e-1)" "unprognostic (2.02e-1)" "unprognostic (9.00e-2)" "unprognostic (1.73e-1)" "unprognostic (6.52e-3)" "unprognostic (3.93e-2)" "prognostic favourable (4.72e-6)" "unprognostic (2.33e-2)" "unprognostic (1.97e-1)" "unprognostic (1.64e-2)" "unprognostic (5.54e-2)" 10.2 28.0 16.9 6.7 19.3 3.7 9.7 15.3 20.8 11.2 11.7 12.0 10.0 11.0 8.4 9.9 10.1 11.7 9.9 19.2 14.6 14.0 36.9 33.0 7.8 7.0 16.5 15.5 12.5 14.0 20.7 14.8 7.8 14.3 9.5 13.0 12.2 12.6 12.2 19.7 9.5 9.6 10.1 12.4 6.6 10.3 25.3 15.8 4.9 10.2 8.4 10.4 8.1 7.7 10.4 11.2 7.4 8.1 12.8 11.4 6.1 13.3 16.7 5.8 6.1 15.9 14.6 11.8 10.2 10.8 15.5 10.1 30.0 7.6 11.4 20.1 9.5 16.9 19.9 20.6 14.0 5.1 9.3 24.4 17.8 23.3 13.3 10.2 4.7 11.7 19.8 12.1 13.4 11.5 17.4 7.7 10.8 20.5 11.5 10.8 6.7 25.1 4.6 18.9 19.2 15.7 9.1 7.3 6.7 25.5 24.7 16.6 22.1 9.2 8.4 17.5 8.3 10.2 10.0 11.1 15.2 10.4 14.8 11.1 8.6 2.5 8.1 7.4 7.6 7.7 9.7 10.4 8.8 11.2 11.2 7.6 10.3 9.3 3.4 12.8 6.0 5.6 11.4 6.1 16.9 19.3 15.3 20.8 14.6 14.0 16.5 15.5 14.3 15.8 NGLY1 "FLJ11005, PNG1" ENSG00000151092 "N-glycanase 1" Q96IV0 3 25718944-25790039 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036825 Approved "Intracellular and membrane" "HPA036825: AB_10672231" "unprognostic (3.65e-2)" "unprognostic (8.65e-2)" "prognostic favourable (1.17e-5)" "unprognostic (2.96e-2)" "unprognostic (1.72e-2)" "unprognostic (1.59e-2)" "prognostic unfavourable (1.96e-6)" "unprognostic (2.20e-1)" "unprognostic (2.34e-1)" "unprognostic (3.73e-3)" "unprognostic (2.55e-1)" "unprognostic (4.23e-2)" "unprognostic (4.92e-3)" "unprognostic (1.07e-2)" "unprognostic (2.47e-1)" "unprognostic (9.08e-2)" "unprognostic (1.89e-2)" 10.7 14.4 11.4 19.6 11.4 12.9 15.0 17.1 15.0 9.5 12.4 6.9 11.7 10.5 10.2 13.8 13.2 8.4 10.5 14.3 12.0 9.0 12.8 18.1 13.9 17.4 9.5 12.5 10.6 20.7 9.0 11.3 8.7 11.0 10.9 15.2 7.8 12.4 18.0 46.6 9.0 11.2 8.7 10.1 14.6 11.9 42.0 9.0 18.0 10.3 10.9 18.1 11.5 10.6 26.1 39.7 19.9 10.8 22.6 14.7 10.3 12.2 10.5 5.9 12.4 11.4 10.4 8.4 10.5 8.9 13.3 12.0 6.5 9.3 31.2 12.0 8.9 5.5 19.8 5.5 18.1 14.7 8.4 23.2 8.0 10.5 12.6 21.3 12.7 9.3 7.5 14.6 13.6 14.2 21.9 22.4 13.5 5.3 25.3 12.6 7.9 19.0 25.9 7.7 22.2 12.2 15.1 3.6 4.4 15.3 14.7 9.7 13.9 17.8 9.6 10.5 10.8 12.6 13.5 27.7 23.8 21.7 12.6 23.1 8.2 19.9 10.8 18.9 13.7 10.1 14.7 26.1 13.8 12.6 16.3 21.7 14.0 13.6 12.8 22.6 8.4 39.7 10.4 10.3 11.4 11.4 17.1 15.0 12.0 9.0 9.5 12.5 11.0 9.0 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122687 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 9.0;K-562: 7.6;SCLC-21H: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavourable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favourable (5.30e-4)" 2.5 3.6 5.0 1.8 6.5 2.1 4.6 2.6 8.5 1.9 3.3 7.1 1.7 3.2 2.0 6.1 2.4 3.5 2.7 3.9 5.0 5.1 1.9 9.0 5.1 4.7 5.4 3.9 3.5 12.2 2.4 2.8 1.0 5.2 3.4 3.0 3.3 5.1 2.8 5.2 8.5 4.3 1.8 5.4 2.4 3.0 2.1 3.8 2.4 3.6 0.9 1.8 2.5 1.8 3.3 7.2 0.6 7.2 2.2 2.5 2.6 3.3 2.0 0.8 0.1 1.8 1.7 0.0 3.4 1.1 1.3 0.7 0.1 2.8 0.1 9.0 2.5 4.0 0.0 2.2 1.0 0.1 1.1 0.5 1.0 0.2 2.8 0.0 2.2 2.9 3.3 1.3 1.2 2.8 7.6 0.1 2.8 3.5 0.0 0.0 0.0 2.0 0.0 0.0 0.1 1.8 3.6 8.0 0.1 6.8 5.7 2.0 4.1 2.2 0.5 0.2 1.7 2.4 0.0 0.1 0.0 0.1 0.1 0.0 3.4 0.5 6.6 0.6 1.1 7.2 1.2 3.3 1.7 0.8 7.2 2.3 2.5 1.6 0.5 2.2 3.2 0.9 1.8 2.6 5.0 6.5 2.6 8.5 5.0 5.1 5.4 3.9 5.2 3.8 NIM1K "MGC42105, NIM1" ENSG00000177453 "NIM1 serine/threonine protein kinase" Q8IY84 5 43192071-43280850 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 23.7;pituitary gland: 9.7" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 4.4;HDLM-2: 4.8;PC-3: 5.5;U-87 MG: 6.0" "Cancer enriched" "Detected in some" 11 "glioma: 6.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 3.2" "Group enriched" "Detected in many" 10 "dendritic cells: 1.2;T-cells: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007695 Uncertain Approved Cytosol Cytosol "HPA007695: " "unprognostic (7.97e-2)" "unprognostic (9.79e-2)" "unprognostic (8.74e-2)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (4.35e-2)" "unprognostic (1.35e-1)" "unprognostic (4.28e-2)" "unprognostic (8.84e-4)" "unprognostic (1.25e-1)" "unprognostic (1.55e-5)" "unprognostic (2.18e-1)" "unprognostic (2.66e-1)" "unprognostic (6.46e-3)" "unprognostic (4.98e-3)" 1.4 3.5 9.4 1.6 10.9 0.9 1.3 4.9 23.7 1.6 1.4 6.3 0.0 1.1 1.2 1.6 1.6 1.4 1.5 1.8 8.7 7.7 1.4 1.2 3.6 1.2 5.6 5.8 1.2 1.5 1.2 9.7 1.8 6.4 1.4 1.7 1.7 2.3 2.4 2.0 1.8 1.2 1.3 4.9 1.0 3.0 1.4 8.1 0.0 2.7 0.0 1.0 1.1 0.8 0.1 1.2 0.0 0.0 0.2 3.2 0.0 0.2 0.6 0.1 0.1 0.9 0.5 0.0 1.0 3.1 1.1 4.4 0.1 0.0 0.4 0.6 0.8 0.3 0.6 0.0 2.7 4.8 0.3 0.1 0.6 0.2 1.6 0.2 0.6 1.9 0.1 0.5 0.0 0.0 0.2 0.3 0.9 0.2 0.3 0.2 0.0 5.5 0.2 0.3 0.5 0.1 0.7 0.9 0.1 1.7 0.5 0.3 0.4 1.5 0.0 0.9 0.8 0.7 0.7 1.6 0.4 0.3 6.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.2 3.2 0.0 9.4 10.9 4.9 11.6 8.7 7.7 5.6 5.8 6.4 8.1 NIT2 ENSG00000114021 "Nitrilase family member 2" Q9NQR4 3 100334701-100361635 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 41.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036999 Approved Supported Centrosome,Cytosol 960000 Cytosol Centrosome "HPA036999: AB_10672105" "unprognostic (3.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.06e-3)" "prognostic unfavourable (4.62e-4)" "unprognostic (6.28e-2)" "unprognostic (2.10e-1)" "unprognostic (4.56e-1)" "unprognostic (1.12e-1)" "unprognostic (6.60e-3)" "unprognostic (2.21e-1)" "unprognostic (6.68e-2)" "unprognostic (7.92e-2)" "unprognostic (1.37e-2)" "unprognostic (4.48e-2)" "unprognostic (1.29e-1)" "unprognostic (8.26e-2)" "unprognostic (1.47e-3)" 9.9 7.4 6.7 5.4 9.9 5.9 12.4 3.7 10.5 6.4 7.2 6.1 10.6 5.5 6.6 13.3 9.2 7.9 7.1 7.4 5.8 6.3 29.8 41.1 5.6 8.9 5.9 8.0 7.2 8.5 4.7 7.6 4.9 7.7 7.2 6.8 11.3 8.2 10.2 14.7 7.7 5.3 7.0 5.4 5.7 6.8 3.3 3.3 4.4 10.8 14.5 10.5 8.2 5.6 4.2 5.9 1.5 2.4 3.0 4.3 1.3 9.9 9.9 1.2 5.1 8.9 12.1 6.2 4.1 6.0 9.7 9.2 8.4 11.2 9.9 6.2 5.8 7.5 4.5 11.0 11.6 3.1 2.3 7.2 3.2 4.3 10.8 4.7 4.9 7.6 16.7 5.1 8.5 6.1 3.3 8.0 11.8 9.4 3.1 4.3 4.4 15.0 3.5 4.2 9.7 16.0 6.2 6.9 3.2 5.6 9.6 6.1 7.1 4.4 4.4 6.1 2.5 2.9 3.5 4.9 5.4 8.5 9.6 7.9 7.6 0.4 2.4 1.1 3.3 2.1 4.3 4.2 3.1 2.5 5.9 3.7 3.6 3.5 1.5 3.0 1.6 1.8 3.1 1.3 6.7 9.9 3.7 10.5 5.8 6.3 5.9 8.0 7.7 3.3 NKTR p104 ENSG00000114857 "Natural killer cell triggering receptor" P30414 3 42600614-42648741 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022120, HPA051576" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "HPA022120: AB_1854513, HPA051576: " "unprognostic (2.73e-3)" "unprognostic (3.11e-1)" "unprognostic (2.33e-1)" "unprognostic (2.06e-1)" "unprognostic (5.27e-3)" "prognostic favourable (1.26e-4)" "unprognostic (4.62e-2)" "unprognostic (5.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "prognostic unfavourable (6.01e-4)" "prognostic unfavourable (5.02e-4)" "unprognostic (3.82e-1)" "unprognostic (4.57e-1)" "unprognostic (1.40e-1)" "prognostic favourable (1.05e-5)" 12.9 14.4 9.8 18.8 22.2 16.3 15.9 42.0 12.3 18.8 10.4 18.5 15.4 11.8 27.2 17.4 11.0 12.0 13.1 11.2 10.9 10.5 9.5 9.7 14.6 15.5 14.5 11.3 22.7 18.4 19.2 26.9 11.1 14.1 12.9 11.1 20.4 13.2 19.5 12.0 20.0 13.3 19.4 15.0 18.5 10.1 17.8 13.8 20.6 14.9 10.9 19.4 12.9 13.9 9.3 8.5 11.7 10.0 11.1 10.2 3.6 8.9 5.1 17.1 7.0 10.2 12.5 9.6 14.5 3.7 6.0 8.2 9.0 7.2 14.1 7.0 4.4 7.9 10.1 3.6 12.4 7.1 8.4 18.1 16.2 14.5 4.4 13.9 11.9 5.1 7.2 11.9 4.5 10.6 18.2 10.9 11.4 3.7 9.5 13.6 14.7 7.5 10.1 7.7 5.8 8.4 6.8 6.0 3.6 15.6 6.5 2.4 9.5 10.1 17.0 10.9 7.9 11.8 14.0 9.5 13.2 9.8 5.8 17.1 6.6 9.2 6.2 11.7 10.2 7.7 9.4 8.9 9.8 8.5 4.7 9.3 10.0 8.7 9.1 11.1 10.0 8.5 8.3 3.6 9.8 22.2 42.0 12.3 10.9 10.5 14.5 11.3 14.1 13.8 NLK ENSG00000087095 "Nemo like kinase" Q9UBE8 17 28041737-28196381 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 32 "basophil: 17.6" "Lineage enriched" "Detected in single" 32 "granulocytes: 17.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018192, HPA056511" Approved Supported "Nucleoplasm,Nucleoli,Cell Junctions" Nucleoplasm "Nucleoli, Cell Junctions" "HPA018192: AB_1854525, HPA056511: " "unprognostic (7.19e-2)" "unprognostic (1.98e-1)" "unprognostic (5.54e-2)" "unprognostic (5.64e-3)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (2.59e-3)" "unprognostic (2.72e-2)" "unprognostic (4.23e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (5.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.92e-1)" "unprognostic (5.27e-2)" "unprognostic (6.57e-2)" 6.4 30.5 19.4 10.9 14.1 7.4 7.5 7.5 38.2 6.2 6.7 8.3 14.4 8.3 5.7 8.8 4.5 5.1 8.2 8.5 18.2 12.0 13.0 8.2 7.1 11.7 15.2 23.6 4.6 11.5 20.8 9.4 9.1 7.0 6.7 7.1 12.7 5.8 17.4 4.9 4.5 8.3 4.6 15.3 10.1 7.0 17.4 7.5 10.9 13.2 3.7 11.0 7.2 4.4 0.5 0.3 17.6 0.3 0.1 0.5 0.2 4.6 5.4 13.0 4.5 2.8 3.6 5.7 4.6 4.7 7.8 6.0 27.0 4.2 6.3 7.1 3.8 4.4 9.1 8.5 9.0 14.5 5.8 24.7 5.0 4.6 4.7 5.2 25.5 4.7 5.2 5.1 6.1 9.1 9.5 7.6 7.1 5.4 13.3 6.0 5.0 2.7 11.2 8.4 4.6 14.1 5.7 9.5 3.5 7.1 6.8 29.0 10.6 8.3 9.3 5.6 7.5 4.6 9.3 9.0 8.6 6.1 5.4 5.6 6.1 17.6 0.2 0.2 0.3 0.3 0.1 0.5 0.4 0.4 0.2 0.3 0.2 0.5 0.1 0.1 0.3 0.3 0.4 0.2 19.4 14.1 7.5 38.2 18.2 12.0 15.2 23.6 7.0 7.5 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722196-65871725 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.7;intermediate monocyte: 5.9;myeloid DC: 4.1;non-classical monocyte: 4.1" "Group enriched" "Detected in many" 5 "dendritic cells: 4.1;monocytes: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria 53000 Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavourable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favourable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 4.5 2.4 7.6 4.7 10.5 2.9 7.3 2.8 11.9 4.1 6.8 5.8 1.0 2.4 5.8 5.0 5.2 3.3 2.7 5.1 7.2 7.6 7.5 18.9 3.4 5.1 8.7 8.5 4.0 11.0 3.6 2.4 4.9 9.8 5.4 6.5 2.0 4.3 2.6 15.0 5.7 5.3 5.5 10.9 5.8 7.5 2.4 6.2 1.8 5.5 7.9 4.0 4.3 3.3 0.9 4.1 0.6 5.9 0.9 0.7 1.8 9.2 8.9 5.3 8.7 6.6 11.4 10.6 9.3 3.9 5.5 6.0 5.0 5.5 13.2 11.8 11.2 7.4 6.8 14.4 9.6 3.9 4.6 3.6 6.6 12.8 5.7 8.3 2.2 8.7 7.9 7.6 9.1 15.5 7.8 2.8 11.8 7.1 5.7 7.5 16.1 2.5 6.7 11.2 20.8 9.0 4.1 16.3 8.5 7.5 7.8 7.7 9.3 9.9 8.9 3.7 4.4 5.3 7.0 2.4 4.8 5.8 5.6 16.3 5.5 0.2 4.7 0.2 0.2 5.9 0.3 0.9 0.4 0.3 4.1 0.9 0.7 0.5 0.6 0.9 4.1 0.2 0.1 1.8 7.6 10.5 2.8 11.9 7.2 7.6 8.7 8.5 9.8 6.2 NME1 "NDPKA, NM23, NM23-H1" ENSG00000239672 "NME/NM23 nucleoside diphosphate kinase 1" P15531 17 51153536-51162428 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008467, CAB040571, HPA041113" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" 28000000 Cytosol "Nucleoplasm, Plasma membrane" "CAB040571: , HPA008467: AB_1079492, HPA041113: " "unprognostic (2.24e-1)" "unprognostic (2.01e-1)" "unprognostic (3.48e-3)" "unprognostic (5.96e-2)" "unprognostic (9.71e-2)" "unprognostic (2.33e-3)" "prognostic unfavourable (2.60e-5)" "unprognostic (4.54e-2)" "unprognostic (3.35e-1)" "unprognostic (2.33e-3)" "unprognostic (2.90e-2)" "unprognostic (1.01e-1)" "prognostic unfavourable (2.07e-9)" "unprognostic (9.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.83e-1)" "unprognostic (9.46e-2)" 25.0 29.5 38.0 28.1 30.1 27.9 29.0 19.6 41.9 16.4 25.4 13.1 10.1 15.1 17.3 22.5 30.1 22.2 13.4 14.1 41.7 39.4 19.6 56.0 14.2 28.5 34.2 34.2 15.6 43.6 13.7 17.3 16.9 38.9 14.5 36.8 14.9 34.3 14.7 14.8 22.4 12.4 29.6 20.5 22.4 13.4 11.6 11.3 19.0 18.8 32.7 41.4 22.8 15.2 24.9 36.2 0.6 19.5 17.2 20.3 18.4 47.6 95.2 32.9 45.9 13.8 22.1 55.3 37.2 25.8 77.1 58.5 74.9 28.9 83.9 38.8 34.4 25.6 62.8 63.2 66.0 40.7 84.6 55.0 73.9 103.9 28.0 60.2 25.2 21.0 39.8 58.0 54.3 46.4 81.1 27.9 45.6 80.7 71.5 69.3 39.4 86.8 43.9 64.9 77.2 59.2 33.3 45.7 52.6 19.5 53.4 34.6 55.6 40.8 29.2 49.8 45.2 30.9 76.3 36.0 83.0 98.8 30.1 51.1 37.8 0.2 15.2 0.6 13.4 19.5 20.3 24.9 14.4 14.6 36.2 17.3 16.4 17.8 0.4 17.2 11.5 20.7 12.1 18.4 38.0 30.1 19.6 41.9 41.7 39.4 34.2 34.2 38.9 11.3 NME2 "NDPKB, NM23-H2" ENSG00000243678 "NME/NM23 nucleoside diphosphate kinase 2" P22392 17 51165435-51171747 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Nucleotide metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB036213, CAB036214, CAB036215, HPA041113" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB036213: , CAB036214: , CAB036215: , HPA041113: " "unprognostic (7.21e-3)" "prognostic unfavourable (4.74e-4)" "unprognostic (4.85e-2)" "unprognostic (1.15e-2)" "unprognostic (8.86e-2)" "unprognostic (1.42e-2)" "prognostic unfavourable (7.09e-4)" "unprognostic (6.62e-3)" "unprognostic (5.68e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (6.41e-2)" "prognostic unfavourable (1.55e-6)" "unprognostic (2.82e-1)" "unprognostic (9.09e-2)" "unprognostic (8.87e-2)" "unprognostic (3.19e-2)" 62.1 54.6 42.3 58.2 44.1 44.2 188.9 20.1 43.7 58.9 74.0 16.3 67.7 52.5 65.0 52.0 104.3 56.8 65.3 115.1 38.2 32.1 77.3 115.7 59.0 174.7 45.0 23.7 90.7 234.3 17.5 30.4 37.9 34.0 64.0 62.7 29.9 109.4 65.8 105.3 63.3 45.1 88.3 34.6 69.4 50.2 32.3 24.4 42.5 66.9 102.0 56.6 81.3 140.8 49.3 71.3 8.3 43.7 32.6 34.5 38.2 91.8 135.0 32.3 56.4 72.3 105.5 89.2 63.7 66.3 97.5 74.3 108.9 48.9 77.3 103.2 65.2 58.8 67.8 86.9 80.3 93.1 200.5 65.0 94.2 157.6 79.0 102.5 45.5 95.5 101.5 62.9 110.7 58.0 88.9 52.1 70.2 163.4 51.3 128.2 48.2 207.4 49.2 107.1 123.4 105.6 116.1 73.7 45.7 39.2 98.5 95.6 67.9 78.7 58.8 94.0 68.0 66.8 101.2 91.1 118.3 88.5 50.8 52.2 47.1 8.3 35.1 2.0 24.7 43.7 34.5 49.3 33.0 26.9 61.5 36.2 23.8 25.6 2.1 32.6 38.0 71.3 29.9 38.2 42.3 44.1 20.1 43.7 38.2 32.1 45.0 23.7 34.0 24.4 NME3 "DR-nm23, NDPKC, NM23-H3" ENSG00000103024 "NME/NM23 nucleoside diphosphate kinase 3" Q13232 16 1770286-1771730 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 30.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041113, HPA052733" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" 7900000 Nucleoplasm Cytosol "HPA041113: , HPA052733: " "prognostic favourable (6.81e-5)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-3)" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (4.54e-2)" "unprognostic (1.13e-1)" "unprognostic (6.22e-3)" "unprognostic (4.40e-2)" "unprognostic (4.43e-2)" "unprognostic (7.09e-3)" "unprognostic (1.79e-1)" "unprognostic (3.84e-1)" "unprognostic (3.64e-1)" "unprognostic (6.11e-3)" 20.6 45.6 18.0 12.9 19.8 6.6 20.0 21.9 18.2 16.6 18.0 11.0 31.6 25.7 14.4 19.1 12.9 14.3 21.5 11.8 17.5 16.1 17.7 11.2 17.3 11.3 18.4 15.9 22.1 26.8 15.1 24.1 9.7 14.4 26.9 6.4 13.8 34.3 41.4 15.2 9.2 24.6 14.6 14.1 20.4 17.5 7.2 14.6 5.1 24.1 11.7 8.8 11.5 17.9 19.3 34.1 15.5 25.6 20.1 24.4 20.0 0.7 11.6 0.2 9.5 2.7 1.4 1.1 6.8 2.0 1.2 0.9 0.0 13.8 0.1 18.9 0.9 9.8 0.6 3.8 0.1 13.5 30.8 0.0 5.4 5.5 5.1 2.3 4.3 6.3 3.4 1.2 0.6 2.4 4.6 1.9 1.1 16.8 0.2 4.5 12.3 9.4 6.4 0.1 18.0 2.0 0.5 13.5 10.4 20.4 15.4 1.6 14.7 5.6 8.5 2.5 9.6 8.1 4.6 4.9 1.5 1.0 3.5 0.4 5.8 4.9 25.6 15.5 17.5 22.9 17.1 19.3 24.4 16.4 22.0 16.3 21.4 16.8 5.3 20.1 24.5 34.1 21.8 20.0 18.0 19.8 21.9 18.2 17.5 16.1 18.4 15.9 14.4 14.6 NME4 "NDPKD, nm23-H4, NM23H4" ENSG00000103202 "NME/NM23 nucleoside diphosphate kinase 4" O00746 16 396725-410367 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid transport, Nucleotide metabolism, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045997, HPA072588" Approved Supported Mitochondria Mitochondria "CAB045997: AB_11126630, HPA072588: " "unprognostic (3.27e-1)" "prognostic unfavourable (6.53e-4)" "unprognostic (3.70e-2)" "unprognostic (7.16e-3)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.40e-2)" "unprognostic (4.46e-3)" "unprognostic (1.98e-1)" "unprognostic (3.12e-1)" "unprognostic (3.74e-2)" "unprognostic (7.79e-3)" "prognostic unfavourable (1.61e-7)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (6.04e-2)" "unprognostic (3.08e-1)" 34.5 34.4 21.5 13.9 17.6 46.8 34.6 10.4 13.6 25.6 44.6 12.8 40.7 9.7 21.7 33.7 25.1 20.0 39.9 26.9 16.6 16.5 20.2 61.2 13.5 27.5 16.9 11.3 31.9 19.2 22.0 17.3 19.4 11.7 46.9 10.6 32.2 44.4 44.0 13.7 7.5 15.3 83.9 12.4 17.8 27.1 13.3 10.9 19.6 21.0 14.2 14.5 64.1 27.5 13.1 28.6 18.2 6.3 1.2 13.7 5.2 0.1 49.5 44.0 60.4 17.6 31.0 9.8 23.3 28.0 35.3 30.3 33.0 28.8 0.4 17.6 37.1 0.6 23.8 25.0 10.4 19.9 35.5 24.0 6.7 44.0 33.3 17.4 8.8 39.9 13.2 21.6 2.1 22.6 24.8 4.3 26.2 40.5 15.2 22.0 44.8 11.0 76.9 9.8 12.5 24.4 0.2 12.9 69.6 5.9 0.4 21.6 29.4 41.0 28.1 25.2 36.7 16.8 5.8 0.5 0.3 13.1 11.0 3.2 29.0 4.1 6.3 18.2 7.5 5.6 6.5 12.3 7.7 8.3 8.7 13.1 13.7 7.1 2.2 1.2 4.8 28.6 0.4 5.2 21.5 17.6 10.4 13.6 16.6 16.5 16.9 11.3 11.7 10.9 NME6 "IPIA-ALPHA, NM23-H6" ENSG00000172113 "NME/NM23 nucleoside diphosphate kinase 6" O75414 3 48290722-48301685 "Enzymes, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017909 Approved Approved Vesicles Vesicles "HPA017909: AB_1854530" "unprognostic (7.31e-3)" "unprognostic (1.87e-1)" "unprognostic (8.19e-3)" "unprognostic (2.09e-2)" "unprognostic (8.52e-2)" "unprognostic (2.20e-1)" "prognostic unfavourable (2.17e-7)" "unprognostic (1.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.00e-3)" "unprognostic (1.32e-1)" "unprognostic (2.98e-1)" "prognostic favourable (3.18e-5)" "unprognostic (1.98e-2)" "unprognostic (1.57e-2)" "unprognostic (1.23e-1)" "unprognostic (9.50e-2)" 11.7 12.2 7.0 14.4 11.0 7.7 13.5 9.2 10.9 12.2 12.0 11.9 14.6 13.5 16.1 13.2 16.1 16.3 8.8 13.7 9.9 6.8 18.0 17.5 11.1 12.9 9.2 10.3 14.5 20.6 12.1 13.3 22.1 8.8 13.2 12.7 13.5 20.8 17.6 20.1 10.3 13.4 13.3 7.1 14.2 13.4 9.0 8.2 12.6 17.5 14.3 15.1 13.9 15.7 26.4 23.5 43.3 22.7 23.0 25.8 14.3 17.8 11.1 15.2 11.0 12.4 16.7 13.6 17.5 13.5 25.8 19.6 18.6 15.7 18.0 9.1 13.6 6.2 13.7 19.3 15.3 21.4 13.2 11.7 14.9 15.1 16.6 14.8 12.6 13.6 21.2 22.8 27.3 13.8 19.6 13.9 9.6 8.5 12.4 6.4 12.8 14.6 7.4 13.3 15.1 12.9 15.4 4.7 8.0 11.9 13.2 15.6 14.7 13.8 12.4 5.1 20.2 12.6 24.9 16.5 22.3 16.2 9.7 19.7 11.3 22.0 20.1 43.3 25.8 20.7 23.6 26.4 24.2 21.9 23.5 24.4 18.7 17.7 22.5 23.0 22.7 21.1 19.4 14.3 7.0 11.0 9.2 10.9 9.9 6.8 9.2 10.3 8.8 8.2 NME7 "CFAP67, FLJ37194, NM23-H7" ENSG00000143156 "NME/NM23 family member 7" Q9Y5B8 1 169132531-169367967 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038014, HPA054289" Uncertain Approved Mitochondria Mitochondria "HPA038014: AB_10673037, HPA054289: " "unprognostic (1.28e-1)" "unprognostic (8.52e-2)" "unprognostic (6.21e-2)" "unprognostic (6.30e-2)" "unprognostic (1.11e-1)" "unprognostic (7.44e-3)" "prognostic unfavourable (3.24e-5)" "unprognostic (1.42e-1)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (2.00e-1)" "unprognostic (6.63e-2)" "unprognostic (2.67e-2)" "unprognostic (1.12e-1)" "unprognostic (7.75e-2)" "unprognostic (2.74e-1)" 7.7 12.1 13.5 8.0 22.8 3.7 12.8 14.6 16.8 15.6 11.5 5.5 13.4 4.6 16.0 15.8 8.6 31.1 11.2 8.4 18.9 11.3 13.9 8.6 8.9 6.0 9.5 11.5 17.0 8.1 18.9 39.9 5.6 15.6 9.6 6.7 9.3 5.9 14.3 5.1 4.9 5.5 17.2 9.5 5.2 8.1 17.2 9.6 11.9 15.9 5.8 7.0 10.0 8.2 8.5 5.2 1.7 7.1 9.1 12.0 4.7 10.5 11.3 12.3 9.6 12.4 12.5 4.4 7.3 11.1 13.3 16.9 6.4 16.0 3.1 13.4 6.5 7.4 6.9 15.8 21.8 11.0 5.7 5.6 10.8 6.5 8.5 10.2 3.6 9.1 9.6 13.4 18.2 19.0 5.3 4.3 13.3 3.4 9.2 7.5 12.1 11.6 7.2 13.3 6.8 21.6 3.1 13.3 19.2 11.1 3.3 8.2 11.4 7.4 11.3 8.3 27.5 7.3 17.7 5.2 8.8 6.5 9.1 3.6 8.2 1.4 3.3 1.7 8.3 5.1 10.1 8.5 10.8 8.8 5.2 7.0 9.3 10.6 1.0 9.1 7.1 4.4 12.0 4.7 13.5 22.8 14.6 16.8 18.9 11.3 9.5 11.5 15.6 9.6 NMNAT1 "LCA9, NMNAT, PNAT1" ENSG00000173614 "Nicotinamide nucleotide adenylyltransferase 1" Q9HAN9 1 9943428-9985501 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Disease mutation, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059447 Approved Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA059447: " "unprognostic (1.94e-1)" "unprognostic (3.81e-3)" "unprognostic (7.54e-3)" "unprognostic (1.01e-1)" "unprognostic (3.50e-1)" "unprognostic (1.73e-1)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (4.45e-3)" "unprognostic (4.55e-2)" "unprognostic (1.12e-1)" "unprognostic (3.57e-1)" "prognostic favourable (3.85e-14)" "unprognostic (3.11e-3)" "unprognostic (1.17e-1)" "unprognostic (1.47e-3)" "unprognostic (5.16e-2)" 7.2 13.2 8.1 7.2 9.0 4.0 8.8 4.1 8.1 8.8 12.8 9.3 11.9 8.9 10.1 8.8 8.7 7.4 7.3 13.9 7.6 6.8 11.5 12.6 5.3 5.6 10.3 8.3 5.1 14.1 10.3 9.3 5.6 13.0 7.0 13.6 10.1 17.7 8.4 29.1 8.1 9.2 8.3 9.0 8.6 7.1 10.7 8.3 6.8 10.8 11.5 6.8 6.2 10.4 5.3 4.3 12.8 4.9 3.1 2.7 2.3 3.7 4.7 6.5 6.3 12.4 11.3 1.5 7.4 6.1 8.7 5.6 2.0 6.5 4.0 4.8 11.3 3.9 7.9 10.6 10.5 8.3 4.0 6.6 2.9 6.1 9.9 5.4 6.5 11.9 12.0 10.5 15.1 9.0 7.7 2.7 9.6 6.4 3.0 3.5 0.8 8.4 3.5 4.0 2.1 10.1 2.1 4.7 2.4 9.8 8.4 8.4 3.1 5.8 8.5 3.6 3.2 7.3 3.4 3.9 3.7 3.9 6.1 11.4 7.3 6.6 4.9 3.9 2.4 3.3 1.1 5.3 2.3 2.7 4.2 3.6 2.1 2.5 12.8 3.1 4.5 4.3 1.9 2.3 8.1 9.0 4.1 8.1 7.6 6.8 10.3 8.3 13.0 8.3 NMNAT2 "C1orf15, KIAA0479, PNAT2" ENSG00000157064 "Nicotinamide nucleotide adenylyltransferase 2" Q9BZQ4 1 183248237-183418602 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.9" "Cell line enhanced" "Detected in many" "HSkMC: 12.7;SCLC-21H: 37.1;U-2197: 21.7;U-87 MG: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061714 Enhanced "HPA061714: " "unprognostic (3.70e-1)" "unprognostic (7.98e-3)" "unprognostic (8.83e-2)" "unprognostic (4.16e-2)" "unprognostic (8.95e-2)" "unprognostic (9.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.35e-1)" "unprognostic (7.92e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.73e-3)" "unprognostic (2.90e-3)" "unprognostic (1.87e-1)" "unprognostic (7.51e-2)" "unprognostic (1.02e-1)" 9.6 7.7 26.2 1.9 34.5 1.0 2.9 53.9 53.5 3.6 2.2 2.0 0.0 1.5 2.5 2.7 1.9 3.8 4.1 19.6 20.6 15.1 1.5 1.1 1.8 1.7 8.6 28.3 1.5 2.9 1.3 17.4 2.0 15.6 1.3 2.1 0.5 1.5 4.1 1.3 1.7 2.0 2.7 4.1 1.2 2.1 8.7 6.3 0.0 7.2 0.0 1.7 1.9 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.2 2.5 0.0 1.5 6.1 2.2 1.6 4.0 0.8 0.2 1.2 2.4 0.0 6.8 0.3 1.0 0.1 0.0 1.6 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 12.7 0.5 1.0 0.2 0.2 0.0 0.0 1.0 0.0 0.0 0.2 4.4 2.4 0.0 0.1 0.0 2.8 2.0 37.1 2.8 0.3 0.1 0.0 0.3 0.6 1.3 1.2 0.4 21.7 1.4 0.3 0.0 0.0 16.9 0.1 0.1 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 26.2 34.5 53.9 34.7 20.6 15.1 8.6 28.3 15.6 6.3 NMNAT3 PNAT3 ENSG00000163864 "Nicotinamide nucleotide adenylyltransferase 3" Q96T66 3 139560180-139678017 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 22.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA039077, HPA057402" Approved Supported Mitochondria Mitochondria "HPA039077: , HPA057402: " "unprognostic (9.45e-3)" "prognostic favourable (9.67e-4)" "unprognostic (2.29e-1)" "unprognostic (1.56e-3)" "unprognostic (2.33e-2)" "unprognostic (2.33e-1)" "unprognostic (2.77e-3)" "unprognostic (6.22e-2)" "unprognostic (9.69e-2)" "unprognostic (1.92e-1)" "prognostic favourable (7.29e-5)" "unprognostic (4.57e-2)" "prognostic favourable (1.95e-5)" "unprognostic (4.13e-2)" "unprognostic (1.63e-1)" "unprognostic (1.44e-1)" "unprognostic (3.07e-1)" 6.2 6.3 9.9 7.0 9.8 14.1 10.8 7.7 9.8 7.4 7.4 6.8 2.7 7.8 7.9 7.3 6.5 11.6 7.9 12.6 11.9 8.1 7.9 6.2 4.7 3.6 7.7 14.0 17.9 10.0 6.2 6.6 1.8 6.7 7.6 6.4 12.7 7.5 4.8 21.9 14.9 6.5 7.3 7.0 4.2 4.8 16.8 8.4 2.4 8.3 9.0 4.8 6.3 6.8 7.2 4.2 11.9 5.0 6.1 5.1 2.1 6.8 2.9 3.3 3.7 0.8 0.7 4.4 2.9 0.3 0.5 0.4 3.9 5.2 4.8 8.7 0.6 3.5 2.2 1.0 0.7 4.3 3.9 22.2 6.3 5.0 1.8 4.2 4.3 1.2 5.8 0.9 1.4 0.4 3.8 10.5 0.5 4.7 3.9 3.7 7.4 2.9 3.5 3.7 3.2 0.9 5.2 7.2 4.4 6.8 3.8 2.5 9.5 11.1 3.9 4.7 10.3 5.6 4.3 17.4 8.3 3.3 3.1 6.7 4.3 11.9 5.0 3.0 4.1 4.5 3.0 3.6 3.6 3.4 3.6 7.2 5.1 5.1 10.8 6.1 4.4 4.2 2.2 2.1 9.9 9.8 7.7 9.8 11.9 8.1 7.7 14.0 6.7 8.4 NMRK1 "bA235O14.2, C9orf95, FLJ20559, NRK1" ENSG00000106733 "Nicotinamide riboside kinase 1" Q9NWW6 9 75060573-75088217 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 29.6;Karpas-707: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049795 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA049795: " "unprognostic (1.12e-1)" "unprognostic (4.13e-2)" "unprognostic (3.58e-2)" "prognostic favourable (3.70e-6)" "unprognostic (3.56e-2)" "unprognostic (2.35e-1)" "unprognostic (5.20e-3)" "unprognostic (2.21e-2)" "unprognostic (3.27e-2)" "unprognostic (2.43e-1)" "unprognostic (2.06e-2)" "unprognostic (1.78e-1)" "prognostic favourable (5.60e-4)" "unprognostic (9.25e-2)" "unprognostic (1.76e-1)" "unprognostic (5.28e-2)" "unprognostic (5.64e-2)" 15.5 7.7 11.1 15.9 10.7 6.9 14.3 21.5 14.6 13.2 15.2 5.8 20.1 12.2 8.1 15.6 24.6 9.4 10.9 9.4 10.2 9.7 22.1 40.3 15.4 19.9 10.8 9.7 15.2 30.6 45.8 18.1 19.7 10.2 15.9 10.3 10.9 29.5 17.7 15.0 15.6 26.6 8.3 8.7 18.8 13.6 6.7 8.9 14.4 31.6 11.2 22.0 12.6 14.8 6.7 8.8 7.3 6.7 8.2 24.2 10.1 5.0 1.1 1.5 3.5 12.1 16.3 8.3 7.4 11.7 1.9 3.0 0.0 13.5 3.0 4.5 7.1 8.9 1.6 5.0 6.0 29.6 1.8 2.1 2.4 2.6 10.8 2.0 0.4 11.3 12.7 3.1 6.4 12.9 0.2 36.5 13.1 3.8 1.9 1.8 1.9 4.7 0.6 13.4 19.2 15.2 9.1 1.0 0.2 3.2 3.3 4.1 8.4 2.1 8.9 6.4 1.2 5.9 2.0 16.2 12.9 1.8 10.5 2.2 6.5 7.3 2.7 4.5 13.9 2.5 16.7 6.7 24.2 16.0 3.1 3.9 22.1 16.7 5.2 8.2 6.7 8.8 15.4 10.1 11.1 10.7 21.5 14.6 10.2 9.7 10.8 9.7 10.2 8.9 NMRK2 "ITGB1BP3, MIBP, NRK2" ENSG00000077009 "Nicotinamide riboside kinase 2" Q9NPI5 19 3933103-3942416 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "heart muscle: 271.6;skeletal muscle: 103.2" "Group enriched" "Detected in some" 7 "BEWO: 22.4;NTERA-2: 18.5" "Cancer enhanced" "Detected in some" "renal cancer: 32.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA049909, HPA054792, HPA072450" Approved Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA049909: , HPA054792: , HPA072450: " "unprognostic (3.61e-1)" "unprognostic (5.92e-2)" "unprognostic (1.18e-2)" "unprognostic (2.54e-1)" "unprognostic (1.03e-1)" "unprognostic (7.61e-2)" "unprognostic (3.30e-2)" "prognostic favourable (1.19e-4)" "unprognostic (1.72e-1)" "unprognostic (3.29e-2)" "unprognostic (5.38e-1)" 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 1.0 0.0 0.0 271.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 1.0 1.9 0.1 103.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 18.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 NMT1 NMT ENSG00000136448 "N-myristoyltransferase 1" P30419 17 45051610-45109016 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022949, HPA022963" Supported Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA022949: AB_1854534, HPA022963: AB_1854535" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "unprognostic (1.30e-2)" "unprognostic (6.14e-2)" "unprognostic (1.65e-1)" "unprognostic (1.64e-1)" "prognostic unfavourable (4.94e-4)" "unprognostic (4.96e-3)" "unprognostic (3.86e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (3.77e-3)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (4.17e-3)" "unprognostic (9.45e-2)" 28.8 32.6 44.9 28.2 37.3 12.0 26.1 34.5 64.3 23.7 24.4 17.2 22.9 23.4 27.3 29.3 26.6 30.9 17.3 26.8 37.7 29.6 28.8 36.6 26.7 27.2 27.7 43.6 29.3 21.8 41.6 23.7 32.7 38.1 23.7 23.1 18.1 34.9 30.1 75.5 28.8 24.8 30.1 36.6 28.2 23.4 26.1 34.0 20.7 29.4 18.6 30.9 25.1 43.3 10.2 18.2 7.6 9.3 7.4 10.0 3.3 16.9 22.4 19.4 17.1 35.1 22.7 20.4 18.9 25.0 36.8 30.4 25.0 14.6 20.4 27.4 26.0 16.0 33.3 26.5 34.2 51.8 23.2 20.3 15.0 24.7 23.1 26.1 24.5 28.6 24.1 27.4 21.8 24.7 32.2 10.4 20.5 14.5 31.7 17.8 18.1 23.5 21.7 28.9 15.5 29.1 15.7 16.2 14.6 11.9 10.9 17.1 23.6 20.7 19.8 22.5 17.3 18.1 25.1 16.1 22.8 20.4 24.1 14.7 23.8 6.5 8.1 7.6 7.9 9.3 7.2 10.2 7.8 9.3 6.6 7.6 10.0 7.6 5.3 7.4 6.9 18.2 7.5 3.3 44.9 37.3 34.5 64.3 37.7 29.6 27.7 43.6 38.1 34.0 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 33.5;HMC-1: 28.0;TIME: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 8.7;eosinophil: 7.9;gdT-cell: 7.2;MAIT T-cell: 12.9;memory CD4 T-cell: 11.5;memory CD8 T-cell: 8.3;naive CD4 T-cell: 14.7;naive CD8 T-cell: 9.3;NK-cell: 12.9;T-reg: 17.5" "Group enriched" "Detected in many" 7 "granulocytes: 8.7;NK-cells: 12.9;T-cells: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 29.3 5.4 18.9 6.5 17.3 3.8 19.2 35.6 25.3 12.0 9.9 6.0 4.7 7.4 14.5 5.0 8.2 8.9 8.1 9.6 12.8 9.2 10.8 18.5 7.2 9.0 8.8 15.0 18.2 7.1 28.5 7.9 5.1 10.3 10.7 10.7 8.3 5.8 9.4 18.8 11.5 11.9 12.5 10.3 10.1 8.8 14.5 9.9 23.7 6.9 4.5 8.9 10.1 20.1 1.9 0.3 8.7 0.5 12.9 17.5 3.9 2.7 3.6 4.1 3.1 11.4 12.3 0.8 6.1 5.0 5.6 7.7 3.5 12.6 0.1 4.3 33.5 3.5 3.7 3.4 9.6 3.7 4.8 7.5 1.7 4.7 7.6 0.5 28.0 10.9 3.6 8.0 2.4 21.8 3.5 0.5 21.0 3.4 5.7 1.4 3.0 3.5 4.3 6.1 0.5 4.2 0.6 1.2 4.8 7.4 1.2 2.0 3.8 2.3 48.6 5.6 8.3 24.8 4.4 4.3 4.5 0.3 6.9 2.0 4.1 8.7 0.3 7.9 7.2 0.4 12.9 1.4 11.5 8.3 0.3 1.9 14.7 9.3 1.2 12.9 0.5 0.2 17.5 3.9 18.9 17.3 35.6 25.3 12.8 9.2 8.8 15.0 10.3 9.9 NNMT ENSG00000166741 "Nicotinamide N-methyltransferase" P40261 11 114257787-114313285 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 97.7" "Cell line enhanced" "Detected in many" "HSkMC: 67.4;LHCN-M2: 40.0;RPTEC TERT1: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059180 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" 15000 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA059180: " "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" "unprognostic (1.61e-2)" "unprognostic (6.14e-2)" "unprognostic (3.51e-1)" "prognostic unfavourable (2.07e-4)" "unprognostic (1.76e-1)" "unprognostic (5.84e-2)" "unprognostic (2.71e-2)" "unprognostic (2.48e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "prognostic unfavourable (1.02e-6)" "prognostic unfavourable (1.75e-4)" "unprognostic (1.11e-1)" "unprognostic (3.37e-3)" "unprognostic (2.77e-2)" 23.7 1.4 0.6 8.8 0.9 0.1 14.6 0.6 1.7 13.1 8.5 0.7 4.9 0.5 15.8 8.7 12.0 8.3 15.3 8.2 1.6 0.0 4.7 97.7 10.0 3.4 1.1 0.6 11.2 2.0 0.6 2.6 8.6 3.3 9.6 3.3 1.6 3.6 6.7 18.3 8.2 4.3 12.4 1.5 5.8 5.1 7.3 0.6 1.3 5.3 2.2 3.1 10.9 35.3 0.6 0.1 0.7 0.2 0.0 0.9 0.0 0.0 4.7 0.0 4.2 24.3 31.6 0.0 6.0 15.9 9.6 19.1 0.0 6.5 0.0 21.4 12.2 0.0 0.0 2.1 9.7 0.0 0.0 0.0 7.4 0.0 33.1 0.0 0.0 67.4 23.3 6.8 10.1 13.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.1 0.0 26.8 0.0 103.7 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 9.3 5.5 22.1 8.5 1.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.2 0.0 0.2 0.1 0.9 0.2 0.0 0.2 0.1 0.6 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.6 0.9 0.6 1.7 1.6 0.0 1.1 0.6 3.3 0.6 NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 100.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004829, CAB004975, HPA066564" Enhanced Approved Mitochondria 1100000 Mitochondria "CAB004975: AB_425908, HPA004829: AB_1079495, HPA066564: " "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (4.81e-2)" "unprognostic (5.02e-2)" "unprognostic (1.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.98e-2)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "prognostic favourable (1.22e-15)" "unprognostic (8.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" 10.8 10.5 11.7 8.3 14.0 7.3 9.1 8.3 19.0 7.6 11.2 7.3 8.8 9.2 7.1 8.8 7.9 5.4 7.1 62.1 10.8 8.2 26.0 48.5 7.2 9.6 9.2 10.3 5.8 12.2 15.6 6.2 5.8 10.0 8.5 12.1 6.7 14.4 7.8 100.0 6.0 8.9 14.7 6.1 6.5 13.6 4.2 6.1 14.0 14.0 32.6 8.7 10.9 6.2 11.4 25.5 13.1 18.5 18.2 19.1 13.5 8.3 6.1 14.2 26.4 16.5 18.4 4.4 8.3 14.2 10.3 9.3 7.1 13.7 8.5 10.4 15.8 7.9 56.2 2.0 10.9 13.5 15.1 12.3 33.0 8.6 9.6 20.6 18.3 15.8 6.3 5.9 8.4 20.3 8.8 34.1 24.4 5.6 22.1 11.1 2.8 5.5 24.8 33.5 30.5 19.5 7.3 21.0 17.4 30.6 0.4 18.9 21.4 20.7 11.1 15.1 14.6 6.3 4.0 18.4 18.9 13.1 3.1 27.4 9.7 9.3 14.2 13.1 14.4 18.4 14.8 11.4 15.6 14.5 25.5 10.3 14.6 13.3 2.4 18.2 18.5 9.2 19.1 13.5 11.7 14.0 8.3 19.0 10.8 8.2 9.2 10.3 10.0 6.1 NOCT "Ccr4c, CCR4L, CCRN4L, NOC" ENSG00000151014 Nocturnin Q9UK39 4 139015789-139045939 "Enzymes, Predicted intracellular proteins" "Biological rhythms" "Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012287, HPA053714" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA012287: , HPA053714: " "unprognostic (2.16e-1)" "unprognostic (2.16e-3)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (3.36e-3)" "unprognostic (2.00e-3)" "unprognostic (3.24e-1)" "prognostic unfavourable (5.28e-5)" "unprognostic (1.86e-1)" "unprognostic (5.64e-3)" "unprognostic (4.63e-2)" "unprognostic (1.01e-3)" "prognostic unfavourable (1.05e-5)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (3.52e-4)" "prognostic unfavourable (6.23e-4)" 17.5 3.9 3.3 4.9 8.0 38.7 7.4 3.2 7.3 2.7 3.1 2.7 0.0 2.2 2.8 1.5 4.0 2.5 7.9 5.4 4.9 3.7 6.9 25.8 5.1 3.1 3.0 3.1 1.7 4.4 4.0 4.7 9.3 3.7 2.0 2.8 1.8 10.8 1.4 12.0 3.9 10.5 4.5 2.3 3.2 3.0 4.9 2.6 3.7 2.9 11.8 3.9 3.7 4.6 1.9 1.5 6.3 3.1 1.4 2.4 0.2 4.8 5.6 2.2 4.2 5.0 2.1 13.7 7.2 5.2 10.3 7.4 7.5 2.0 16.0 5.8 5.3 3.5 11.5 6.3 9.7 7.2 4.7 7.4 3.4 6.5 4.6 10.8 4.4 2.4 3.1 11.4 7.8 4.5 13.3 5.3 4.5 5.5 7.4 5.7 7.1 6.0 6.1 6.5 5.6 6.9 3.1 8.3 5.5 4.5 5.2 4.1 3.8 8.4 6.7 5.5 7.2 5.2 8.6 4.3 4.0 10.1 5.1 21.5 7.0 1.5 1.4 0.8 2.4 1.5 1.4 1.1 1.1 1.3 0.6 1.9 0.8 1.6 6.3 1.4 3.1 1.5 0.7 0.2 3.3 8.0 3.2 7.3 4.9 3.7 3.0 3.1 3.7 2.6 NOS1 "nNOS, NOS" ENSG00000089250 "Nitric oxide synthase 1" P29475 12 117208142-117452170 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 13.4;skeletal muscle: 36.3" "Cell line enhanced" "Detected in some" "HaCaT: 6.2;RH-30: 12.8;RPTEC TERT1: 8.0;U-2 OS: 2.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002167, HPA058312, HPA069509" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB002167: AB_564073, HPA058312: , HPA069509: " "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.18e-2)" "unprognostic (6.64e-3)" "unprognostic (4.91e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-1)" "unprognostic (9.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (7.56e-2)" "unprognostic (1.01e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-4)" "unprognostic (1.87e-1)" 0.5 0.6 3.8 3.5 13.4 0.7 0.6 4.4 4.8 0.7 2.0 1.1 0.0 0.5 0.6 0.7 1.3 0.8 0.5 0.5 2.8 4.4 1.9 0.5 1.4 0.6 2.4 1.6 0.5 1.9 0.4 0.8 0.4 5.9 1.6 0.9 0.6 3.8 0.6 36.3 2.2 0.6 0.8 1.2 0.5 0.5 0.9 3.0 0.0 0.6 0.0 0.5 0.9 0.6 0.9 0.6 2.1 0.5 0.8 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 6.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 1.4 0.0 12.8 0.1 8.0 0.0 0.3 1.3 0.0 0.0 0.0 0.1 0.0 0.1 0.1 2.5 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.0 2.1 0.5 0.5 0.5 0.4 0.4 0.7 0.4 0.3 0.2 0.9 0.5 0.5 1.9 0.8 0.5 0.6 0.3 0.0 3.8 13.4 4.4 4.8 2.8 4.4 2.4 1.6 5.9 3.0 NOS2 "HEP-NOS, iNOS, NOS, NOS2A" ENSG00000007171 "Nitric oxide synthase 2" P35228 17 27756766-27800499 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.8;lymphoid tissue: 15.6" "Group enriched" "Detected in some" 8 "CACO-2: 16.6;SCLC-21H: 13.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB002014 Enhanced "CAB002014: " "unprognostic (1.95e-3)" "unprognostic (3.08e-3)" "unprognostic (4.75e-3)" "unprognostic (4.42e-3)" "unprognostic (3.49e-1)" "unprognostic (2.13e-2)" "unprognostic (5.61e-2)" "unprognostic (5.09e-2)" "unprognostic (9.91e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "unprognostic (1.34e-1)" "unprognostic (6.04e-2)" "unprognostic (8.02e-2)" "unprognostic (3.68e-1)" "unprognostic (8.69e-2)" "unprognostic (4.03e-2)" 1.0 0.7 1.6 15.6 1.6 0.0 0.5 1.5 7.3 0.4 6.8 0.0 0.0 11.8 0.4 0.0 1.0 0.5 0.4 0.7 1.3 1.1 1.7 0.2 3.8 1.8 1.0 2.2 1.0 0.3 0.1 2.1 3.4 0.4 0.9 9.0 1.2 0.2 0.2 0.7 0.4 20.8 1.7 0.8 0.2 0.3 0.4 0.2 0.2 0.5 5.3 1.7 5.4 0.3 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.6 1.5 7.3 1.3 1.1 1.0 2.2 0.4 0.2 NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150990995-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.6" "Cell line enhanced" "Detected in some" "BEWO: 11.2;HUVEC TERT2: 21.5;K-562: 7.6;TIME: 39.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basal ganglia: 32.4;cerebral cortex: 12.4;hippocampal formation: 18.8;pons and medulla: 35.3" "Low cell type specificity" "Detected in many" "Lineage enriched" "Detected in many" 5 "T-cells: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavourable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" 11.4 4.5 3.1 7.5 32.4 1.9 25.6 1.8 12.4 4.6 3.2 1.7 1.0 4.0 8.3 2.5 4.7 5.0 6.6 35.2 18.8 3.4 5.5 5.4 14.0 10.3 4.7 1.7 4.5 4.1 2.7 4.8 11.5 35.3 5.2 2.5 5.2 3.0 3.2 6.0 4.9 4.0 5.4 25.9 70.6 3.6 4.5 1.6 0.0 5.9 2.1 2.4 5.1 7.3 1.1 0.5 0.7 0.4 0.5 5.3 1.2 0.2 0.0 0.6 1.9 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.1 1.0 0.2 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 1.0 0.1 2.9 0.3 0.2 5.0 0.0 0.1 0.0 0.0 21.5 7.6 1.8 0.0 0.0 0.1 0.2 0.8 0.0 1.4 0.0 0.8 0.0 0.1 0.2 0.2 0.1 0.7 0.0 0.1 0.6 39.2 0.1 0.4 0.1 0.0 1.2 4.0 1.0 0.0 3.5 0.0 0.3 0.3 0.2 2.5 0.4 1.5 0.8 3.9 2.2 0.5 1.1 5.3 2.1 0.7 0.5 0.4 0.5 4.4 1.2 3.1 32.4 1.8 12.4 18.8 3.4 4.7 1.7 35.3 1.6 NOSIP CGI-25 ENSG00000142546 "Nitric oxide synthase interacting protein" Q9Y314 19 49555711-49590262 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 119.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043464, HPA062132" Approved Enhanced Nucleoplasm Nucleoplasm "HPA043464: AB_10794284, HPA062132: AB_2684693" "unprognostic (2.27e-1)" "unprognostic (4.69e-2)" "unprognostic (1.39e-1)" "unprognostic (4.17e-2)" "unprognostic (1.59e-2)" "unprognostic (9.46e-2)" "unprognostic (1.47e-2)" "unprognostic (9.42e-2)" "unprognostic (3.79e-1)" "unprognostic (1.25e-1)" "unprognostic (2.27e-2)" "unprognostic (9.73e-2)" "unprognostic (3.97e-2)" "unprognostic (2.15e-1)" "unprognostic (9.76e-2)" "unprognostic (1.02e-1)" "unprognostic (2.95e-3)" 13.4 13.9 14.2 14.0 14.0 14.3 11.5 12.1 14.2 11.3 15.9 12.3 13.1 17.3 12.5 8.1 12.7 11.1 11.7 14.9 12.3 11.4 13.2 14.5 12.6 24.6 18.3 10.8 12.9 39.7 7.1 13.6 15.6 14.3 11.6 7.9 11.3 19.2 11.4 66.9 11.9 16.5 11.0 13.1 18.0 13.9 40.2 16.3 20.6 15.5 17.6 16.3 11.7 15.0 20.4 21.5 31.8 16.8 29.7 119.4 69.2 66.1 35.9 14.0 30.9 12.5 9.2 13.5 15.7 13.9 26.3 24.3 25.0 11.7 17.8 27.5 13.1 14.9 13.8 27.5 11.5 20.3 39.7 22.5 20.7 27.8 19.8 18.2 19.0 11.9 19.1 20.0 10.9 15.9 24.9 14.2 13.7 17.7 18.5 39.2 19.0 31.2 24.2 23.3 15.8 12.2 20.0 17.5 22.8 21.1 18.0 15.7 14.7 19.3 23.4 22.9 19.4 7.9 29.9 26.8 50.5 24.1 8.7 25.1 17.7 28.0 16.8 23.5 35.1 15.7 45.4 20.4 71.4 40.2 16.6 19.8 119.4 65.8 31.8 29.7 14.3 21.5 37.5 69.2 14.2 14.0 12.1 14.2 12.3 11.4 18.3 10.8 14.3 16.3 NPEPL1 "bA261P9.2, FLJ11583" ENSG00000215440 "Aminopeptidase like 1" Q8NDH3 20 58689131-58719238 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.2;classical monocyte: 13.4;eosinophil: 4.9;intermediate monocyte: 8.9;myeloid DC: 8.2;neutrophil: 9.6;non-classical monocyte: 11.9" "Group enriched" "Detected in all" 5 "dendritic cells: 8.2;granulocytes: 12.2;monocytes: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004986, CAB017025, HPA036356" Approved Approved Nucleoplasm 16000 Nucleoplasm "CAB004986: AB_426073, CAB017025: , HPA036356: " "unprognostic (1.68e-1)" "unprognostic (5.87e-3)" "unprognostic (8.28e-2)" "unprognostic (2.78e-1)" "unprognostic (5.42e-2)" "unprognostic (1.47e-3)" "unprognostic (2.86e-3)" "unprognostic (3.11e-2)" "unprognostic (4.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.62e-3)" "unprognostic (3.78e-2)" "prognostic unfavourable (1.87e-9)" "unprognostic (7.97e-2)" "unprognostic (1.64e-1)" "unprognostic (2.21e-1)" "prognostic favourable (5.73e-4)" 17.2 10.3 9.9 9.7 15.3 15.8 25.0 24.2 10.1 9.6 14.9 10.2 17.2 14.4 11.9 23.5 17.9 12.5 24.5 19.4 10.1 8.6 16.7 11.9 14.5 12.6 12.9 7.2 12.5 15.6 13.6 11.4 11.2 13.1 15.0 4.5 15.7 19.1 17.2 51.8 15.2 13.7 25.8 10.0 16.5 12.8 13.0 9.0 5.6 16.5 20.4 11.8 15.3 20.4 1.0 8.2 12.2 13.4 2.0 2.3 4.1 9.1 12.9 2.3 1.9 5.2 9.6 0.7 3.4 0.3 11.6 6.5 7.4 7.0 0.4 19.2 6.6 9.9 3.2 4.4 1.1 8.1 2.8 3.0 9.9 3.2 13.2 3.3 5.5 9.4 13.7 4.0 0.0 9.7 0.4 1.4 4.5 43.0 1.3 8.7 3.4 13.4 2.6 1.1 5.0 4.7 5.9 4.3 1.3 9.4 2.6 17.3 10.0 6.3 10.2 2.9 2.3 5.8 1.8 4.5 1.6 0.3 4.2 6.3 1.1 12.2 13.4 4.9 1.9 8.9 2.3 1.0 1.1 1.3 8.2 0.7 0.7 1.3 9.6 2.0 11.9 0.4 2.3 4.1 9.9 15.3 24.2 10.1 10.1 8.6 12.9 7.2 13.1 9.0 NPEPPS "MP100, PSA" ENSG00000141279 "Aminopeptidase puromycin sensitive" P55786 17 47522942-47623276 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021453, HPA045649" Uncertain Supported Cytosol 2100000 Cytosol "HPA021453: , HPA045649: " "unprognostic (1.63e-1)" "unprognostic (3.15e-2)" "prognostic favourable (3.39e-5)" "unprognostic (2.66e-2)" "unprognostic (1.53e-1)" "unprognostic (5.92e-2)" "prognostic unfavourable (3.67e-5)" "unprognostic (3.84e-2)" "unprognostic (1.22e-1)" "unprognostic (1.77e-1)" "unprognostic (3.85e-2)" "unprognostic (3.63e-2)" "unprognostic (1.93e-1)" "unprognostic (8.55e-2)" "unprognostic (1.52e-1)" "unprognostic (1.23e-2)" "unprognostic (1.07e-1)" 16.0 26.0 27.2 15.9 27.7 11.1 56.1 36.5 33.8 17.1 17.7 9.8 14.6 14.6 16.9 17.1 47.7 17.2 16.3 22.2 24.0 15.6 18.8 11.1 30.3 24.1 16.0 29.7 20.8 16.8 21.2 15.3 17.6 27.2 18.6 20.0 13.3 21.8 16.5 52.3 29.6 17.3 20.4 22.8 15.7 16.2 15.3 16.1 7.0 14.5 14.8 18.1 19.0 30.5 6.9 9.0 23.2 8.6 9.3 9.2 5.4 32.6 21.5 21.7 15.2 25.1 25.3 45.8 14.4 18.7 21.9 21.3 13.8 37.6 19.5 22.4 21.0 19.9 23.8 13.3 34.1 8.7 20.6 23.5 22.2 16.1 14.5 13.2 15.2 19.3 13.1 15.9 8.3 22.5 19.8 11.4 31.0 8.8 17.5 11.8 13.3 19.6 14.2 30.5 17.2 27.3 24.0 17.4 15.0 18.6 10.8 12.8 80.9 9.2 28.7 14.6 10.5 21.8 10.1 23.3 22.4 11.9 20.7 7.0 9.6 10.2 8.6 10.7 9.1 6.6 9.2 6.8 7.3 8.5 8.7 6.9 6.5 7.6 23.2 9.3 6.8 9.0 8.4 5.4 27.2 27.7 36.5 33.8 24.0 15.6 16.0 29.7 27.2 16.1 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 76.0" "Cell line enhanced" "Detected in many" "Karpas-707: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 76.0" "Group enriched" "Detected in many" 36 "granulocytes: 76.0;monocytes: 23.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" 190000 Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavourable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavourable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 14.9 6.8 10.9 14.2 12.3 12.4 5.3 3.5 10.2 3.9 5.3 15.0 11.4 2.4 2.5 23.7 8.0 4.1 10.1 4.7 9.2 8.7 37.4 15.4 14.3 20.4 16.0 8.6 2.8 3.2 2.5 2.5 32.9 15.4 4.4 7.4 3.9 5.7 5.8 2.4 6.5 4.8 5.8 15.3 32.1 4.0 4.0 14.4 3.1 3.4 1.3 10.9 11.8 5.5 0.7 1.3 76.0 23.6 0.0 1.3 10.3 2.7 0.5 0.8 0.0 2.4 2.4 0.7 0.9 1.8 1.0 0.5 0.0 1.2 7.3 1.3 0.0 1.1 1.6 2.0 0.2 0.0 1.2 11.6 0.3 0.1 1.3 4.3 6.9 1.9 7.7 0.2 0.0 0.1 8.7 11.7 1.8 0.9 0.2 2.9 9.3 0.9 1.1 0.6 8.9 0.2 6.1 2.6 3.9 4.2 0.2 3.7 2.4 7.1 0.2 1.0 2.0 0.6 0.1 8.4 10.1 7.4 2.1 7.8 3.0 3.6 23.6 18.0 1.0 20.8 0.9 0.3 0.8 0.9 1.3 0.7 0.7 0.9 76.0 0.0 16.0 0.2 1.3 10.3 10.9 12.3 3.5 10.2 9.2 8.7 16.0 8.6 15.4 14.4 NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678637-153693992 "Enzymes, FDA approved drug targets, Predicted membrane proteins" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 98.4" "Cell line enriched" "Detected in some" 6 "ASC diff: 59.1" "Cancer enhanced" "Detected in all" "ovarian cancer: 39.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "olfactory region: 23.0" "Region enhanced" "Detected in many" "olfactory region: 11.1" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavourable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favourable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" 41.1 4.3 0.5 5.9 0.9 0.1 98.4 0.5 0.8 8.1 8.2 0.3 7.3 1.2 16.8 11.1 8.7 25.0 9.3 19.6 0.9 0.5 28.7 3.7 34.8 8.6 0.7 0.0 19.5 4.2 7.8 4.5 11.8 2.5 4.9 1.5 2.0 2.0 9.0 6.9 3.4 4.6 15.6 2.2 1.2 5.0 6.4 0.2 0.8 7.6 5.1 1.1 11.6 26.5 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 59.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.8 0.0 7.1 0.0 0.0 0.1 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.5 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 2.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.5 0.8 0.9 0.5 0.7 0.0 2.5 0.2 NQO1 "DHQU, DIA4, DTD, NMOR1, QR1" ENSG00000181019 "NAD(P)H quinone dehydrogenase 1" P15559 16 69706996-69726951 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 142.1" "Cell line enhanced" "Detected in many" "A549: 162.9;Hep G2: 143.8;SiHa: 185.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007308, CAB012421" Enhanced Enhanced Cytosol 310000 Cytosol "CAB012421: , HPA007308: AB_1079501" "unprognostic (1.04e-2)" "unprognostic (1.95e-3)" "unprognostic (3.14e-1)" "unprognostic (3.76e-3)" "unprognostic (9.03e-2)" "prognostic unfavourable (1.45e-4)" "unprognostic (1.05e-3)" "unprognostic (1.97e-1)" "unprognostic (5.07e-2)" "unprognostic (1.24e-2)" "unprognostic (1.49e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-2)" "unprognostic (6.36e-2)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.27e-1)" 31.3 24.2 12.8 6.4 20.7 0.6 77.1 2.7 9.1 7.6 23.2 7.8 5.7 29.5 3.9 8.6 36.3 8.2 77.2 9.3 9.9 7.5 44.7 1.2 17.2 6.9 11.3 6.0 3.7 2.5 7.0 3.7 3.5 25.5 9.8 20.8 20.2 10.5 7.6 7.6 2.3 17.7 22.7 10.4 6.0 142.1 3.8 4.9 0.1 25.7 69.7 16.2 21.2 18.9 5.2 3.2 0.9 3.2 15.1 12.3 4.4 14.3 162.9 13.7 61.0 34.1 49.4 5.1 24.3 43.7 25.1 38.8 19.8 93.0 0.4 28.9 125.7 15.0 5.3 27.4 12.9 5.8 0.2 0.7 40.4 143.8 45.2 3.4 11.7 11.6 17.4 43.5 5.0 62.2 5.9 1.0 134.1 46.5 0.6 6.3 7.2 15.9 1.1 2.9 6.6 50.0 52.2 4.9 1.1 185.1 26.3 108.3 42.5 11.4 42.1 25.3 10.5 9.4 19.1 0.8 3.2 0.6 32.4 1.8 125.1 0.6 3.2 0.2 5.7 0.3 2.9 5.2 6.6 7.2 3.2 2.1 2.1 4.7 0.9 15.1 0.3 1.2 12.3 4.4 12.8 20.7 2.7 9.1 9.9 7.5 11.3 6.0 25.5 4.9 NQO2 "DHQV, DIA6, NMOR2, QR2" ENSG00000124588 "N-ribosyldihydronicotinamide:quinone reductase 2" P16083 6 2987987-3028869 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 62.1" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021283, HPA021332" Enhanced Supported Nucleoplasm,Cytosol 6500000 Cytosol Nucleoplasm "HPA021283: AB_1854600, HPA021332: AB_1854601" "unprognostic (7.11e-3)" "unprognostic (1.43e-3)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.00e-2)" "unprognostic (3.58e-1)" "prognostic unfavourable (8.40e-4)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (4.90e-2)" "unprognostic (6.59e-2)" "unprognostic (3.60e-2)" "unprognostic (8.28e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-2)" "unprognostic (3.96e-1)" "unprognostic (2.02e-1)" 24.7 45.6 18.2 11.0 17.6 27.2 21.9 44.3 28.1 12.9 11.5 8.9 8.8 15.6 10.4 15.4 12.1 11.2 12.8 38.2 16.0 13.3 82.9 47.0 11.7 17.5 17.0 23.5 13.5 18.4 12.1 9.3 12.1 24.5 12.7 9.0 18.0 24.5 13.5 41.3 20.2 15.5 10.7 11.8 15.3 12.8 7.7 12.5 7.0 11.9 13.9 7.9 10.4 11.0 3.2 16.6 62.1 25.2 7.3 9.3 13.1 12.6 21.4 13.0 28.7 23.1 13.7 14.0 12.3 15.8 11.3 12.8 22.5 4.8 11.1 44.9 21.1 9.7 13.4 8.5 8.9 25.8 11.4 6.8 26.3 22.5 18.8 6.8 21.8 8.4 10.2 13.8 12.8 11.0 38.9 6.6 9.4 28.1 7.8 12.7 17.7 17.8 14.6 15.6 32.4 17.1 6.8 2.8 5.1 18.6 8.0 39.0 10.9 4.7 19.0 10.7 4.2 14.3 5.3 14.5 32.8 3.4 12.6 20.8 21.1 5.6 25.2 13.5 9.2 15.7 6.6 3.2 8.3 8.3 16.6 2.1 5.0 5.7 62.1 7.3 13.9 1.7 9.3 13.1 18.2 17.6 44.3 28.1 16.0 13.3 17.0 23.5 24.5 12.5 NRBP1 "BCON3, MADM, MUDPNP, NRBP" ENSG00000115216 "Nuclear receptor binding protein 1" Q9UHY1 2 27427790-27442259 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029527, CAB033078" Supported Supported Cytosol 38000 Cytosol "CAB033078: AB_2154375, HPA029527: AB_10601379" "unprognostic (4.95e-3)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (1.38e-1)" "unprognostic (3.62e-2)" "unprognostic (3.95e-1)" "prognostic unfavourable (2.22e-5)" "unprognostic (7.36e-2)" "unprognostic (1.44e-1)" "unprognostic (6.11e-2)" "unprognostic (3.13e-1)" "unprognostic (2.60e-1)" "prognostic unfavourable (5.84e-5)" "unprognostic (1.26e-1)" "unprognostic (2.69e-1)" "unprognostic (2.75e-2)" "unprognostic (3.48e-3)" 30.8 27.6 20.9 30.8 25.9 49.8 29.1 31.6 38.4 36.3 35.2 21.3 27.5 27.3 40.6 34.2 52.2 28.7 29.9 27.7 18.0 26.0 24.6 38.8 27.1 25.6 21.5 26.2 36.6 28.2 23.0 27.0 58.7 33.9 30.3 25.4 30.6 31.6 34.7 62.2 36.6 31.5 40.7 18.3 29.1 28.9 46.9 20.6 24.4 25.4 39.4 37.6 34.2 37.7 20.6 29.1 57.9 37.2 27.5 33.7 32.9 30.0 30.2 25.0 33.1 38.7 38.7 30.4 28.6 36.1 41.0 31.9 30.5 12.3 8.7 21.5 45.5 20.8 24.8 25.8 26.5 17.0 15.4 17.3 12.3 40.0 32.5 9.7 23.3 31.6 32.5 41.8 28.0 45.0 9.7 13.8 35.9 45.3 12.7 23.3 31.4 19.1 9.9 53.4 9.7 29.1 20.9 6.7 19.0 33.9 24.5 17.8 13.4 10.8 35.5 36.2 36.0 21.6 23.1 29.2 29.0 10.4 28.3 16.9 18.1 53.6 28.5 57.9 33.2 37.2 29.2 20.6 28.6 29.9 29.1 18.1 26.3 27.0 38.2 27.5 33.3 18.6 33.7 32.9 20.9 25.9 31.6 38.4 18.0 26.0 21.5 26.2 33.9 20.6 NRBP2 DKFZp434P086 ENSG00000185189 "Nuclear receptor binding protein 2" Q9NSY0 8 143833594-143840974 "Enzymes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.5" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB020944, HPA029051, HPA029052" Approved Approved Cytosol Cytosol "CAB020944: , HPA029051: , HPA029052: AB_10602714" "unprognostic (1.84e-1)" "unprognostic (4.66e-2)" "unprognostic (2.54e-2)" "unprognostic (1.53e-3)" "unprognostic (1.01e-1)" "unprognostic (2.00e-2)" "unprognostic (4.03e-1)" "unprognostic (2.86e-1)" "unprognostic (3.97e-1)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (2.47e-2)" "prognostic unfavourable (2.01e-5)" "unprognostic (3.86e-2)" "unprognostic (3.98e-1)" "unprognostic (4.56e-2)" "unprognostic (2.04e-1)" 18.5 10.7 21.6 6.8 21.1 1.9 10.0 17.5 32.6 7.6 13.3 47.5 8.7 8.8 11.2 10.0 9.9 14.6 11.3 15.2 23.5 14.9 14.0 18.9 14.9 4.9 30.9 23.6 10.7 10.4 8.4 8.8 6.1 30.2 17.8 6.9 10.1 22.1 15.5 7.6 23.0 9.3 12.3 54.1 7.5 10.1 6.1 27.5 1.0 9.0 3.6 3.8 8.2 7.8 0.5 0.0 0.0 0.4 0.0 1.5 0.3 5.8 7.3 6.7 8.2 10.4 16.1 1.5 12.0 5.2 4.3 6.4 1.7 5.5 0.6 3.2 14.3 9.5 3.9 4.2 1.7 7.1 2.9 1.1 19.4 3.0 10.7 0.0 2.8 20.6 9.9 2.2 2.2 6.0 3.7 7.8 9.2 2.5 0.5 0.3 2.5 4.1 2.0 6.2 2.7 5.9 2.0 2.4 4.9 15.3 7.8 6.0 11.2 0.4 13.9 2.6 7.9 12.4 3.8 4.3 0.2 0.1 13.8 2.4 3.5 0.0 0.4 0.0 0.2 0.2 1.5 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 21.6 21.1 17.5 21.4 23.5 14.9 30.9 23.6 30.2 27.5 NRDC "hNRD1, hNRD2, NRD1" ENSG00000078618 "Nardilysin convertase" O43847 1 51789191-51878937 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 96.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053661 Approved Nucleoplasm Nucleoplasm "HPA053661: " "unprognostic (1.22e-1)" "unprognostic (6.52e-2)" "unprognostic (2.14e-2)" "unprognostic (5.62e-2)" "unprognostic (2.61e-1)" "unprognostic (3.25e-2)" "prognostic unfavourable (5.49e-6)" "unprognostic (1.42e-1)" "unprognostic (4.17e-2)" "unprognostic (1.67e-1)" "unprognostic (5.86e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (2.12e-9)" "unprognostic (2.75e-1)" "unprognostic (2.35e-2)" "unprognostic (9.54e-2)" "unprognostic (5.53e-3)" 16.4 15.9 13.4 15.8 17.5 14.5 11.7 14.7 16.9 12.2 13.7 11.0 9.9 11.2 11.8 12.1 14.4 10.9 10.9 25.7 13.1 13.3 12.4 28.5 12.0 13.6 16.2 10.6 11.7 15.9 19.3 21.4 14.2 15.7 13.8 12.1 9.8 11.9 11.3 96.4 19.1 10.3 13.3 14.0 13.6 11.9 32.3 14.5 19.4 11.7 21.5 15.1 13.0 16.0 13.8 18.5 36.3 19.1 15.8 15.1 16.2 47.6 26.8 26.9 38.7 28.3 43.9 31.4 48.1 41.6 35.0 37.2 18.8 18.8 31.4 25.8 36.2 27.8 39.6 37.3 44.4 37.2 19.5 37.5 36.5 16.3 29.1 32.7 28.6 34.9 28.6 51.1 47.5 36.4 49.4 21.1 43.8 17.4 29.6 11.3 47.8 28.9 29.0 32.2 34.6 25.9 27.7 25.9 19.5 43.9 35.3 26.0 23.6 39.9 30.2 30.8 28.6 33.5 40.9 31.5 47.6 29.4 36.4 41.3 35.3 19.3 18.1 26.0 13.7 19.1 13.7 13.8 12.7 15.1 18.5 9.3 12.5 13.4 36.3 15.8 14.5 15.0 14.4 16.2 13.4 17.5 14.7 16.9 13.1 13.3 16.2 10.6 15.7 14.5 NRK DKFZp686A17109 ENSG00000123572 "Nik related kinase" Q7Z2Y5 X 105822543-105958610 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 42.2;placenta: 64.8" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 32.4;HSkMC: 6.2;RH-30: 7.3;RPTEC TERT1: 19.9" "Cancer enriched" "Detected in some" 8 "testis cancer: 6.1" "Region enriched" "Detected in single" 10 "cerebellum: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 28 "cerebellum: 16.0" "Low region specificity" "Detected in many" HPA017238 Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA017238: AB_1854645" "unprognostic (2.64e-4)" "unprognostic (9.82e-2)" "unprognostic (5.98e-3)" "unprognostic (5.52e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (1.35e-2)" "unprognostic (6.08e-2)" "unprognostic (3.24e-2)" "unprognostic (5.28e-3)" "unprognostic (1.47e-3)" "unprognostic (1.14e-1)" "unprognostic (4.28e-2)" "unprognostic (6.80e-3)" 2.6 12.7 0.4 2.7 0.4 0.0 0.8 4.3 0.3 3.5 1.5 0.1 4.6 0.0 4.3 15.6 1.6 1.3 7.5 2.9 0.4 0.4 9.9 0.4 0.5 0.0 0.3 0.0 42.2 0.5 0.0 2.9 64.8 0.2 22.0 0.1 0.0 2.1 1.6 0.4 0.4 0.5 2.8 0.4 0.3 0.9 10.6 0.0 0.0 0.5 3.1 0.3 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 6.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 7.3 0.0 19.9 0.4 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 4.3 0.3 0.4 0.4 0.3 0.0 0.2 0.0 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300215 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA048431: , HPA070333: , HPA073705: " "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 11.8 13.2 11.9 25.4 15.7 23.9 14.0 28.9 16.7 15.6 14.2 18.5 17.0 10.6 19.0 13.9 17.8 13.6 15.8 11.7 12.8 11.5 14.4 10.5 12.3 19.4 12.9 11.7 16.6 27.1 24.6 19.3 16.0 13.4 14.2 14.3 13.8 13.5 18.7 20.6 16.1 14.5 15.6 13.2 16.1 13.1 28.1 16.1 27.3 20.1 10.6 22.7 13.4 20.2 10.2 8.9 18.7 10.8 10.9 7.8 2.9 9.7 12.6 13.1 11.3 6.4 8.3 0.4 8.8 8.9 12.4 11.6 2.8 8.2 20.1 10.0 12.1 8.4 20.8 19.6 15.1 34.0 12.6 8.9 14.2 0.1 10.7 19.2 10.6 7.8 11.9 14.7 13.8 18.0 12.1 7.1 12.5 20.4 13.3 6.2 14.2 11.1 14.8 1.7 6.2 8.0 11.8 15.9 11.0 22.9 10.0 6.9 10.0 16.0 13.3 8.7 12.6 5.5 10.9 8.3 7.2 14.4 5.0 9.4 9.3 10.7 9.1 9.4 7.5 6.1 6.3 8.5 6.3 5.0 6.7 10.2 7.8 6.3 18.7 10.9 10.8 8.9 5.7 2.9 11.9 15.7 28.9 16.7 12.8 11.5 12.9 11.7 13.4 16.1 NSD2 "KMT3G, MMSET, WHSC1" ENSG00000109685 "Nuclear receptor binding SET domain protein 2" O96028 4 1871424-1982207 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015801, CAB068246, CAB068247" Enhanced Supported Nucleoplasm Nucleoplasm "CAB068246: , CAB068247: , HPA015801: AB_1858830" "unprognostic (3.70e-1)" "unprognostic (9.80e-2)" "unprognostic (3.33e-2)" "unprognostic (1.77e-1)" "unprognostic (4.01e-1)" "unprognostic (1.31e-2)" "prognostic unfavourable (2.61e-4)" "unprognostic (3.24e-2)" "unprognostic (6.22e-2)" "unprognostic (7.66e-2)" "unprognostic (2.09e-1)" "unprognostic (9.25e-3)" "prognostic unfavourable (7.19e-4)" "unprognostic (3.89e-2)" "unprognostic (2.95e-1)" "unprognostic (1.31e-1)" "unprognostic (6.15e-2)" 8.7 7.6 17.6 11.5 16.2 35.1 8.5 20.6 18.2 7.0 14.8 12.4 6.3 14.0 9.5 7.4 12.7 6.8 6.9 11.9 15.1 10.9 8.4 7.5 11.1 18.8 14.7 16.1 7.0 11.7 10.7 11.8 9.8 14.6 8.7 17.7 9.4 10.2 7.4 11.8 12.1 14.6 10.5 15.3 13.5 11.0 26.3 13.4 46.7 13.8 5.5 17.7 8.6 9.4 4.9 3.9 4.1 1.8 2.7 4.3 0.6 27.4 13.9 41.9 18.3 4.5 6.7 12.2 22.2 19.7 27.2 30.5 12.2 32.6 29.6 7.6 18.3 12.0 27.0 18.3 46.8 14.2 11.1 35.2 19.2 7.2 5.7 21.5 18.5 2.6 4.6 23.9 23.0 21.4 19.0 31.1 22.3 10.8 57.5 22.6 17.6 16.0 32.9 27.3 10.2 11.2 13.0 26.0 20.8 18.2 6.8 8.3 16.1 14.5 16.5 27.2 20.3 17.2 44.6 14.6 15.4 26.8 16.3 21.4 25.2 2.1 1.7 1.7 2.9 1.8 3.2 1.8 3.2 3.2 1.5 4.9 2.8 2.3 4.1 2.7 1.4 3.9 4.3 0.6 17.6 16.2 20.6 18.2 15.1 10.9 14.7 16.1 14.6 13.4 NSD3 "FLJ20353, KMT3F, WHISTLE, WHSC1L1" ENSG00000147548 "Nuclear receptor binding SET domain protein 3" Q9BZ95 8 38269697-38382272 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005659, CAB013721, HPA018893" Uncertain Approved Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB013721: , HPA005659: AB_1080596, HPA018893: AB_1858833" "unprognostic (6.21e-2)" "unprognostic (3.73e-2)" "unprognostic (2.18e-2)" "unprognostic (4.12e-1)" "unprognostic (2.25e-1)" "unprognostic (1.53e-2)" "unprognostic (4.35e-2)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.72e-2)" "prognostic unfavourable (7.48e-4)" "unprognostic (5.06e-2)" "unprognostic (5.60e-3)" "unprognostic (6.69e-2)" "unprognostic (4.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.60e-2)" 19.2 11.3 31.1 15.8 31.4 36.3 20.1 51.5 37.7 18.5 15.5 16.7 14.0 16.2 16.0 12.5 17.0 16.8 17.0 12.7 24.4 16.6 14.2 11.2 17.9 22.3 25.0 26.8 26.5 16.3 21.0 24.2 22.5 21.9 16.4 18.7 12.3 18.3 17.9 12.3 16.2 17.7 16.0 15.3 17.2 19.7 9.3 25.6 16.7 19.2 6.9 20.4 19.6 23.3 26.7 5.6 26.2 5.1 8.6 18.0 2.9 23.9 13.8 23.7 16.0 16.6 19.2 17.6 20.1 22.3 17.4 20.3 7.3 13.3 28.6 18.5 13.7 14.4 18.7 16.1 24.9 11.3 11.0 36.4 11.1 8.6 17.1 16.0 13.2 10.3 16.4 15.7 32.1 20.0 25.8 19.0 16.5 8.6 46.7 13.6 16.1 6.5 21.4 25.9 9.0 12.4 18.6 13.4 18.1 16.3 14.3 14.0 18.1 12.2 19.0 18.2 18.9 27.0 11.8 17.0 20.2 27.6 15.3 16.2 13.1 13.9 5.1 9.1 8.0 2.4 5.3 16.5 12.0 7.1 4.1 26.7 15.0 6.3 26.2 8.6 1.5 5.6 18.0 2.9 31.1 31.4 51.5 37.7 24.4 16.6 25.0 26.8 21.9 25.6 NSDHL "H105e3, SDR31E1, XAP104" ENSG00000147383 "NAD(P) dependent steroid dehydrogenase-like" Q15738 X 152830967-152869729 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease mutation, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000248, HPA000571" Enhanced Enhanced "Endoplasmic reticulum,Lipid droplets" "Endoplasmic reticulum" "Lipid droplets" "HPA000248: AB_1079507, HPA000571: AB_1079506" "unprognostic (1.84e-1)" "prognostic favourable (5.65e-4)" "unprognostic (2.66e-1)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (5.04e-4)" "unprognostic (1.03e-1)" "unprognostic (5.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.62e-2)" "unprognostic (2.63e-1)" "prognostic favourable (6.09e-5)" "unprognostic (3.53e-2)" "unprognostic (1.36e-1)" "unprognostic (3.91e-2)" "unprognostic (4.79e-2)" 17.4 24.8 11.0 7.7 10.5 6.0 20.4 7.7 15.0 13.4 23.4 13.9 20.5 13.3 10.4 35.7 36.2 11.9 7.4 16.7 14.3 11.4 11.6 38.1 9.9 8.7 9.7 10.4 9.8 7.9 9.8 6.9 7.9 18.9 12.0 10.7 7.9 12.2 17.7 6.9 14.5 24.0 9.9 14.2 7.3 9.6 8.6 9.3 6.0 11.0 22.2 17.0 7.5 16.1 16.2 17.5 16.4 17.7 17.0 17.3 13.0 43.6 16.1 21.9 11.4 18.9 14.4 12.4 8.7 11.7 15.9 20.3 22.2 23.9 21.6 29.4 11.8 22.5 28.5 40.2 14.1 7.2 16.3 8.8 15.7 22.4 13.8 8.8 7.2 17.6 15.6 31.1 7.9 14.7 14.6 9.8 12.0 19.3 8.7 11.5 8.7 19.4 6.5 15.9 17.7 33.0 18.1 7.9 9.0 7.8 11.7 9.2 7.7 11.3 12.4 7.4 12.3 17.8 16.7 13.9 9.3 37.2 13.7 13.8 7.0 16.4 17.7 15.8 15.6 16.2 15.7 16.2 15.6 13.5 17.5 12.9 11.4 12.6 1.9 17.0 12.1 15.6 17.3 13.0 11.0 10.5 7.7 15.0 14.3 11.4 9.7 10.4 18.9 9.3 NSF "SEC18, SKD2" ENSG00000073969 "N-ethylmaleimide sensitive factor, vesicle fusing ATPase" P46459 17 46590669-46757464 "Enzymes, Predicted intracellular proteins, Transporters" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 35.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003154, CAB009324, HPA071089" Enhanced Enhanced Cytosol 6900 Cytosol "CAB009324: AB_653479, HPA003154: AB_1079508, HPA071089: " "unprognostic (5.70e-2)" "unprognostic (1.50e-1)" "unprognostic (1.07e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.09e-1)" "unprognostic (3.95e-2)" "unprognostic (5.48e-2)" "unprognostic (2.37e-2)" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" "unprognostic (2.07e-2)" "unprognostic (3.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.74e-1)" 1.9 3.6 11.2 2.7 19.1 1.6 2.6 14.1 35.4 2.5 4.0 1.4 1.9 2.7 3.9 2.2 2.8 1.5 13.9 14.4 3.4 2.5 2.2 3.1 12.6 1.3 3.5 6.5 5.5 2.6 2.8 5.5 2.4 2.1 4.3 2.4 3.2 2.2 3.1 1.6 3.0 3.1 3.6 3.4 3.3 1.0 7.2 15.5 10.4 13.3 6.7 11.1 8.8 6.1 13.6 9.1 0.6 5.4 7.6 7.4 8.4 9.8 8.1 7.9 9.3 0.0 15.0 15.1 18.6 1.1 10.2 3.1 13.3 5.3 13.3 0.5 9.8 12.7 8.0 0.4 3.3 6.9 4.3 16.4 6.8 12.7 10.0 8.2 17.9 12.0 10.0 3.9 5.1 16.2 7.2 8.8 14.0 9.2 12.8 8.4 9.5 12.4 0.0 5.9 15.5 18.6 10.3 22.9 8.1 12.1 12.5 17.6 10.1 8.8 6.4 8.1 16.1 10.4 13.3 7.8 8.2 12.1 8.9 6.8 8.2 10.5 15.5 7.2 6.9 8.1 6.0 6.7 12.1 6.2 11.1 8.8 NSMCE1 NSE1 ENSG00000169189 "NSE1 homolog, SMC5-SMC6 complex component" Q8WV22 16 27224991-27268794 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041567, HPA043091" Supported Supported Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA041567: AB_10964260, HPA043091: AB_10962722" "unprognostic (6.27e-2)" "unprognostic (8.17e-2)" "unprognostic (2.52e-2)" "unprognostic (2.48e-3)" "unprognostic (4.17e-1)" "unprognostic (4.52e-3)" "unprognostic (1.59e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.91e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-3)" "unprognostic (3.58e-1)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" 24.0 37.3 26.7 33.3 27.4 16.9 30.1 16.9 27.2 22.2 24.7 31.4 30.8 14.1 23.1 32.5 34.7 36.0 36.7 21.7 24.3 26.3 30.9 37.4 27.1 36.7 31.9 20.9 29.5 45.3 46.7 20.5 21.4 27.1 33.8 21.2 26.0 37.2 31.5 22.5 19.5 23.8 35.4 32.4 20.9 26.2 55.4 19.3 41.5 33.9 25.7 29.3 27.6 20.4 42.0 38.9 31.8 27.7 60.4 41.6 32.6 14.4 20.8 14.3 15.5 23.2 31.2 11.5 15.5 15.8 11.8 12.3 16.1 35.3 28.5 37.2 23.5 15.6 26.7 46.4 15.3 34.8 18.5 13.1 19.3 30.8 40.5 15.3 9.9 30.5 32.4 29.6 56.7 15.8 17.5 9.0 21.7 24.4 20.0 17.0 12.6 14.4 17.6 17.6 44.5 34.1 9.4 15.1 13.7 10.5 14.7 26.4 24.3 18.4 9.8 14.3 9.0 16.3 14.8 27.0 19.4 21.9 30.8 15.2 6.1 31.8 27.7 25.0 25.2 24.3 27.8 24.1 36.0 30.6 38.9 42.0 41.6 32.6 9.0 60.4 22.5 37.7 32.8 32.6 26.7 27.4 16.9 27.2 24.3 26.3 31.9 20.9 27.1 19.3 NSUN2 "FLJ20303, Misu, MRT5, TRM4" ENSG00000037474 "NOP2/Sun RNA methyltransferase family member 2" Q08J23 5 6599239-6633291 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis, tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037896 Supported Approved Nucleoplasm Nucleoplasm "HPA037896: AB_10670532" "unprognostic (3.99e-2)" "unprognostic (5.73e-2)" "unprognostic (1.44e-1)" "unprognostic (7.66e-3)" "unprognostic (8.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.44e-3)" "unprognostic (5.12e-2)" "unprognostic (4.48e-2)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (2.48e-2)" "prognostic unfavourable (5.69e-5)" "unprognostic (1.98e-1)" "unprognostic (1.47e-1)" "unprognostic (4.30e-3)" "unprognostic (1.70e-2)" 19.0 19.1 11.3 20.4 17.4 16.7 28.1 13.4 16.0 17.4 17.9 20.2 18.2 15.4 21.5 20.6 27.0 19.3 17.1 20.1 12.7 9.7 15.0 34.9 15.0 22.5 13.6 16.5 17.2 18.7 19.5 22.3 18.2 16.1 15.5 21.2 14.3 20.0 15.8 42.3 22.9 20.9 19.1 15.9 23.7 19.9 15.8 13.2 26.7 14.3 17.1 29.5 19.2 17.1 18.1 16.7 15.6 17.3 17.6 22.7 12.7 26.9 23.4 13.8 12.1 8.8 9.8 32.5 21.1 12.8 22.5 19.6 30.4 20.2 46.5 21.6 16.9 20.7 28.5 24.6 30.6 31.7 23.0 27.7 55.5 17.6 12.6 47.7 22.4 11.2 18.2 25.5 22.3 15.9 35.7 17.1 20.8 18.8 26.0 20.7 22.8 30.6 34.0 14.5 14.3 15.8 30.0 13.2 18.6 52.2 26.5 20.3 23.1 21.3 18.5 18.0 23.7 18.6 31.4 14.1 26.5 44.6 14.4 38.0 20.6 9.7 14.6 15.6 17.5 17.3 22.7 18.1 18.4 20.7 16.7 16.5 20.4 20.6 2.9 17.6 15.2 16.5 13.0 12.7 11.3 17.4 13.4 16.0 12.7 9.7 13.6 16.5 16.1 13.2 NT5C1A "CN-I, CN-IA, CN1, CN1A, MGC119199, MGC119201" ENSG00000116981 "5'-nucleotidase, cytosolic IA" Q9BXI3 1 39659121-39672038 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 51.9;tongue: 13.9" "Cell line enriched" "Detected in some" 13 "SH-SY5Y: 19.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050283, HPA054158" Supported "HPA050283: , HPA054158: " "unprognostic (7.85e-2)" "unprognostic (1.60e-1)" "unprognostic (6.19e-1)" "unprognostic (1.51e-3)" "unprognostic (7.19e-2)" "unprognostic (2.87e-1)" "unprognostic (3.34e-1)" "unprognostic (1.32e-1)" "unprognostic (3.29e-2)" "unprognostic (1.81e-2)" 0.7 2.8 1.2 0.8 3.0 0.5 0.5 5.6 7.6 0.7 0.5 1.0 0.0 0.5 0.6 2.9 3.0 0.7 0.5 9.8 1.7 1.7 0.9 0.5 0.5 0.5 1.8 4.9 0.7 6.0 0.5 0.5 0.5 6.9 0.9 0.5 0.0 0.7 0.7 51.9 0.5 0.6 0.6 5.2 0.5 0.6 0.7 1.0 0.0 0.5 13.9 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 19.9 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.0 5.6 7.6 1.7 1.7 1.8 4.9 6.9 1.0 NT5C1B "AIRP, CN-IB" ENSG00000185013 "5'-nucleotidase, cytosolic IB" Q96P26 2 18562872-18589572 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 52.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA056683 Uncertain "HPA056683: " "unprognostic (4.18e-2)" "unprognostic (1.20e-2)" "unprognostic (7.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "unprognostic (4.97e-2)" "unprognostic (4.96e-2)" "unprognostic (4.84e-1)" "unprognostic (8.49e-2)" "unprognostic (4.42e-2)" "unprognostic (2.91e-2)" "unprognostic (2.35e-1)" "unprognostic (1.61e-1)" "unprognostic (6.96e-2)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (3.77e-1)" 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.3 0.7 0.0 0.4 0.3 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.8 0.1 0.1 0.1 0.1 0.5 52.6 0.1 0.1 0.5 0.1 0.1 0.5 0.1 1.2 3.7 0.0 0.1 0.7 2.6 0.4 3.2 0.7 0.3 0.0 0.0 0.0 0.5 2.5 0.0 0.0 0.0 0.0 3.5 1.6 0.5 0.0 1.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.9 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 1.1 0.2 0.0 2.9 0.1 0.2 0.7 1.7 0.3 0.7 0.8 0.1 3.0 2.5 1.2 2.6 0.4 1.5 0.8 0.7 1.7 1.5 1.0 2.9 0.5 1.0 0.7 2.0 2.5 0.0 1.2 0.0 0.1 0.0 1.3 0.0 2.3 0.1 1.3 1.3 0.3 1.2 2.6 2.2 0.0 0.7 0.1 3.7 0.5 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 NT5C2 "cN-II, GMP, NT5B, PNT5, SPG65" ENSG00000076685 "5'-nucleotidase, cytosolic II" P49902 10 103088017-103193306 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Allosteric enzyme, Hydrolase" "Cancer-related genes, Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003751 Approved "HPA003751: AB_1854664" "unprognostic (8.18e-2)" "unprognostic (1.98e-1)" "unprognostic (2.55e-2)" "unprognostic (2.46e-1)" "unprognostic (5.54e-2)" "unprognostic (4.87e-3)" "unprognostic (2.24e-2)" "unprognostic (1.72e-1)" "unprognostic (6.41e-2)" "unprognostic (9.59e-2)" "unprognostic (2.93e-3)" "unprognostic (6.20e-2)" "unprognostic (3.26e-2)" "unprognostic (3.70e-2)" "unprognostic (6.40e-2)" "unprognostic (3.43e-1)" "unprognostic (1.50e-1)" 15.0 17.0 17.6 18.2 21.2 31.6 19.7 22.5 19.6 17.5 20.7 25.4 24.5 10.9 24.6 19.6 38.6 14.8 17.0 16.5 16.7 20.7 19.6 15.5 18.8 16.8 21.8 17.3 24.8 19.4 18.7 29.5 16.9 29.1 22.9 17.0 26.2 67.2 21.6 41.6 11.7 13.9 20.4 19.1 20.5 15.9 21.7 14.5 29.7 39.2 16.3 31.5 21.1 31.1 6.7 9.7 23.8 14.5 10.5 8.7 7.1 50.1 20.4 14.2 31.9 12.5 14.0 8.1 25.2 24.5 12.3 12.7 14.8 40.2 24.0 19.6 17.4 25.7 9.4 12.9 14.4 14.5 8.8 17.3 8.7 14.4 22.4 25.0 8.6 21.4 14.4 10.7 17.3 11.2 11.2 16.8 21.2 29.6 22.3 32.4 13.5 25.3 36.5 12.3 6.9 17.6 28.7 4.3 10.7 13.2 10.4 19.7 15.9 19.4 11.4 9.8 9.8 14.0 18.3 14.7 24.4 32.2 9.9 28.9 2.8 19.8 11.7 23.8 8.1 11.9 8.7 6.7 7.0 6.5 9.7 4.2 6.0 6.2 21.4 10.5 14.5 7.3 6.5 7.1 17.6 21.2 22.5 18.0 16.7 20.7 21.8 17.3 29.1 14.5 NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014113-33062797 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010630, HPA029058" Uncertain "Intracellular and membrane" "HPA010630: AB_2668319, HPA029058: AB_10601380" "unprognostic (7.50e-2)" "unprognostic (3.10e-1)" "unprognostic (1.14e-1)" "unprognostic (2.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.56e-2)" "prognostic unfavourable (2.42e-4)" "unprognostic (3.25e-2)" "unprognostic (3.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "prognostic unfavourable (1.70e-4)" "unprognostic (9.37e-2)" "unprognostic (2.05e-1)" "unprognostic (2.12e-3)" "unprognostic (3.43e-3)" 12.3 12.1 9.9 17.0 9.9 15.4 11.4 16.2 12.2 12.0 27.5 7.4 8.1 20.9 14.7 11.6 12.0 9.0 12.9 11.6 9.8 10.3 11.7 10.5 11.6 15.0 10.3 9.8 10.3 19.1 5.5 10.9 10.6 8.4 9.6 27.2 8.5 9.0 8.9 53.3 15.0 19.7 7.5 9.9 18.4 14.5 6.3 8.9 15.4 9.8 28.8 22.8 12.0 11.6 21.4 6.8 36.6 11.4 8.6 18.9 13.3 14.1 10.3 9.6 8.5 7.3 6.4 7.8 15.5 10.1 10.5 14.4 6.4 40.0 35.5 9.0 9.0 21.5 10.4 10.2 15.7 5.5 13.3 16.1 12.2 9.3 7.7 19.2 13.4 7.1 9.1 11.5 23.1 6.9 13.9 9.5 12.9 9.6 7.1 30.1 9.9 9.1 9.5 8.8 21.0 33.6 14.9 10.4 12.9 10.1 19.1 24.2 12.7 10.7 6.0 9.0 8.1 15.3 20.2 19.0 21.6 17.4 7.4 11.9 14.0 26.9 8.0 29.8 9.0 10.2 10.2 21.4 12.1 11.0 6.8 20.5 12.4 10.6 36.6 8.6 11.4 6.4 18.9 13.3 9.9 9.9 16.2 12.2 9.8 10.3 10.3 9.8 8.4 8.9 NT5C3B "cN-IIIB, MGC20781, NT5C3L" ENSG00000141698 "5'-nucleotidase, cytosolic IIIB" Q969T7 17 41825181-41836263 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030786, HPA057095" Approved "HPA030786: AB_10602716, HPA057095: " "unprognostic (3.90e-2)" "unprognostic (5.75e-2)" "unprognostic (8.87e-2)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "prognostic unfavourable (8.11e-5)" "unprognostic (3.40e-2)" "unprognostic (6.05e-2)" "unprognostic (2.31e-1)" "prognostic favourable (2.67e-4)" "unprognostic (3.07e-1)" "unprognostic (7.17e-3)" "unprognostic (2.36e-2)" "unprognostic (4.80e-3)" "unprognostic (7.14e-3)" "unprognostic (1.42e-2)" 10.0 12.4 15.9 8.3 26.2 3.2 18.3 22.8 31.2 11.6 15.6 8.4 10.1 4.4 14.1 21.3 13.9 12.6 11.5 11.4 15.0 14.9 19.2 19.4 11.0 7.9 12.9 16.4 15.5 19.6 21.1 13.7 11.5 13.2 12.6 13.8 12.6 15.9 20.1 7.8 8.6 8.1 22.1 6.7 7.7 12.0 24.8 9.8 1.4 37.8 5.6 10.7 13.3 9.7 5.3 5.2 2.5 5.6 1.0 5.9 4.1 8.6 12.9 22.0 29.0 20.3 17.1 3.1 8.6 25.2 27.6 27.5 10.5 5.0 12.9 4.5 17.6 8.3 21.8 12.2 44.8 6.3 8.6 7.8 13.4 11.1 13.5 0.1 3.2 12.1 11.7 23.3 19.0 15.9 7.3 8.1 19.4 5.0 12.5 3.0 5.9 1.9 10.7 29.3 11.9 12.0 9.3 13.5 6.9 13.0 46.6 4.6 12.6 4.7 10.9 8.5 6.7 14.2 17.7 1.6 6.6 6.3 11.1 0.2 10.4 1.5 5.6 0.5 3.8 1.0 5.8 4.7 5.9 5.1 5.2 5.3 5.4 4.5 2.5 1.0 0.7 2.7 0.8 4.1 15.9 26.2 22.8 31.2 15.0 14.9 12.9 16.4 13.2 9.8 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 108.8;TIME: 63.0;U-87 MG: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 13.4;memory CD8 T-cell: 6.6;naive B-cell: 19.9;naive CD8 T-cell: 17.3" "Group enriched" "Detected in many" 47 "B-cells: 19.9;T-cells: 17.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" 1600000 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavourable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavourable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavourable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 12.2 3.2 9.3 7.7 11.6 0.5 16.6 1.1 6.9 58.8 13.9 3.6 8.1 18.6 33.3 14.8 7.6 12.2 15.4 6.1 5.7 5.5 8.8 26.0 3.4 6.8 6.3 6.6 25.4 1.4 1.6 9.3 42.2 5.3 16.4 15.6 15.3 4.6 17.8 5.7 4.5 14.9 35.3 6.3 7.0 6.0 12.4 4.2 1.6 26.5 7.3 7.1 16.6 20.2 19.9 0.0 0.2 0.0 0.4 17.3 3.9 5.4 2.9 5.0 0.1 11.5 36.7 0.0 35.5 38.9 17.5 32.9 0.0 54.5 0.0 12.8 31.0 2.8 0.0 35.7 41.7 0.0 0.0 0.0 0.8 0.6 5.7 0.0 0.0 9.4 0.4 35.7 22.8 14.5 0.0 0.1 108.8 0.9 0.0 0.0 0.1 3.9 0.1 1.1 0.1 37.9 2.4 0.0 0.6 0.4 2.2 12.0 0.0 0.9 63.0 14.3 0.1 18.0 57.7 2.7 1.7 0.0 98.1 0.0 44.8 0.0 0.0 0.2 2.0 0.0 3.5 13.4 2.3 6.6 0.0 19.9 2.4 17.3 0.2 0.4 0.0 0.0 0.8 3.9 9.3 11.6 1.1 6.9 5.7 5.5 6.3 6.6 5.3 4.2 NTHL1 "NTH1, OCTS3" ENSG00000065057 "Nth like DNA glycosylase 1" P78549 16 2039815-2047866 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase, Lyase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025152 Supported "CAB025152: " "unprognostic (1.06e-1)" "unprognostic (9.71e-2)" "unprognostic (1.23e-1)" "unprognostic (2.54e-1)" "unprognostic (7.89e-2)" "unprognostic (1.77e-1)" "unprognostic (2.86e-1)" "unprognostic (2.46e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "unprognostic (2.77e-2)" "unprognostic (6.78e-2)" "unprognostic (6.53e-2)" "unprognostic (2.27e-1)" "unprognostic (1.34e-1)" "unprognostic (5.08e-2)" "unprognostic (1.62e-2)" 10.5 8.2 13.4 10.5 19.9 6.0 7.8 15.6 17.9 14.8 12.3 9.0 15.1 9.7 11.8 6.9 9.4 20.5 14.7 10.6 12.5 12.1 7.4 17.5 11.1 10.4 13.6 15.7 18.8 24.6 5.8 8.7 8.3 13.3 9.8 8.2 9.1 22.2 18.2 12.4 6.3 11.2 7.8 10.4 15.2 11.1 6.4 11.6 9.6 9.5 6.6 8.4 7.8 9.3 21.4 14.7 2.4 14.2 9.7 18.8 8.5 10.7 26.4 7.7 11.6 3.1 6.0 8.5 4.5 4.8 8.6 5.4 18.8 10.5 22.9 9.5 3.7 9.6 9.5 10.6 1.5 10.6 23.3 7.1 16.7 20.8 4.3 8.1 8.4 5.0 5.5 4.5 4.9 11.9 7.7 8.3 3.3 12.0 12.1 30.4 17.1 17.3 29.0 8.1 36.7 6.2 3.9 16.3 16.3 4.9 15.1 8.7 10.8 8.0 4.6 7.3 8.1 6.5 8.3 11.3 13.2 9.3 3.3 11.4 9.1 2.4 8.7 2.0 8.8 14.2 9.8 21.4 10.5 9.8 14.7 17.1 7.8 9.5 0.3 9.7 12.1 14.6 18.8 8.5 13.4 19.9 15.6 17.9 12.5 12.1 13.6 15.7 13.3 11.6 NTMT1 "AD-003, C9orf32, HOMT1A, METTL11A, NRMT, NRMT1" ENSG00000148335 "N-terminal Xaa-Pro-Lys N-methyltransferase 1" Q9BV86 9 129608884-129636131 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020092, HPA058420" Uncertain Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA020092: AB_1853831, HPA058420: " "unprognostic (4.74e-3)" "unprognostic (1.77e-1)" "unprognostic (2.44e-1)" "unprognostic (1.48e-1)" "unprognostic (1.17e-1)" "unprognostic (1.24e-3)" "unprognostic (4.17e-3)" "unprognostic (4.92e-2)" "unprognostic (1.24e-1)" "unprognostic (8.57e-2)" "unprognostic (3.63e-1)" "unprognostic (4.35e-2)" "unprognostic (1.00e-3)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "unprognostic (5.58e-2)" "unprognostic (3.50e-3)" 10.2 25.7 11.9 11.5 13.1 13.8 10.0 13.2 15.3 8.9 10.7 9.0 14.4 11.7 8.8 13.6 10.2 7.8 16.6 31.8 11.5 11.5 11.7 16.8 8.9 11.5 15.7 11.3 8.8 19.5 9.4 10.8 12.1 13.8 10.2 7.4 9.4 13.0 11.4 54.6 10.7 10.2 13.6 10.3 13.1 10.5 56.2 10.7 10.8 12.3 22.1 9.8 12.3 14.5 27.1 28.4 20.3 34.2 14.8 26.6 19.4 16.6 34.5 14.3 24.2 9.1 13.6 15.4 31.7 18.8 32.1 27.8 28.3 21.9 21.4 16.3 22.6 32.5 30.0 27.9 20.2 16.5 16.1 8.9 31.1 28.5 29.3 18.0 13.6 14.5 14.2 33.6 16.8 17.5 32.8 16.1 16.7 55.1 20.3 24.3 18.7 30.2 19.3 16.9 43.0 12.9 9.5 29.1 15.2 15.6 29.3 21.6 24.4 9.4 11.8 38.6 19.6 35.8 33.2 12.7 15.1 32.6 17.6 18.7 22.1 15.1 27.3 20.3 25.2 28.7 24.8 23.4 25.5 26.6 26.4 27.1 26.4 22.0 7.6 14.8 34.2 28.4 23.4 19.4 11.9 13.1 13.2 15.3 11.5 11.5 15.7 11.3 13.8 10.7 NTPCR "C1orf57, HCR-NTPase, MGC13186" ENSG00000135778 "Nucleoside-triphosphatase, cancer-related" Q9BSD7 1 232950605-232983882 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028125, HPA054304" Uncertain Approved Cytosol Cytosol "HPA028125: AB_10601091, HPA054304: " "unprognostic (2.67e-1)" "unprognostic (2.28e-2)" "unprognostic (1.63e-2)" "unprognostic (7.59e-2)" "unprognostic (5.85e-3)" "unprognostic (1.04e-1)" "unprognostic (8.70e-3)" "unprognostic (2.12e-1)" "unprognostic (6.00e-2)" "unprognostic (5.03e-3)" "unprognostic (4.78e-2)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.74e-2)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "unprognostic (6.37e-3)" 5.4 9.8 13.2 5.8 14.9 2.5 8.7 14.5 15.9 9.9 8.0 11.1 4.1 5.1 9.6 9.5 8.0 11.3 9.6 10.3 13.3 13.1 8.4 6.1 7.4 6.5 13.7 10.8 12.9 13.4 16.9 8.0 6.3 18.5 8.8 10.3 10.8 10.1 10.0 26.8 9.9 6.8 9.9 12.6 6.3 5.8 11.2 11.0 5.7 13.6 11.1 6.5 7.1 7.4 2.4 1.5 3.3 1.8 1.6 4.3 1.3 2.5 6.1 7.0 3.5 5.2 6.9 0.1 1.7 5.4 5.2 7.1 4.3 2.9 3.9 3.8 3.4 3.3 4.7 6.2 5.7 2.8 8.8 1.1 3.8 5.5 5.4 2.1 2.4 9.1 12.2 5.1 5.1 4.2 3.4 6.0 6.1 1.8 5.4 5.5 6.9 7.3 3.5 4.6 5.6 7.7 3.0 6.1 10.2 2.4 2.0 2.4 5.1 4.8 3.2 4.3 3.6 4.7 4.7 6.8 5.5 4.4 5.1 5.1 6.2 1.1 1.6 0.8 2.1 1.8 2.5 1.6 3.0 1.3 1.5 2.4 4.3 3.5 3.3 1.6 1.6 0.6 3.5 1.3 13.2 14.9 14.5 15.9 13.3 13.1 13.7 10.8 18.5 11.0 NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815640-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adrenal gland: 15.8;blood: 32.3;brain: 28.3" "Cell line enriched" "Detected in some" 4 "HMC-1: 41.1" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Region enriched" "Detected in many" 5 "pons and medulla: 28.3" "Cell type enriched" "Detected in single" 127 "basophil: 32.3" "Lineage enriched" "Detected in single" 323 "granulocytes: 32.3" "Region enhanced" "Detected in some" "basal ganglia: 8.2" "Low region specificity" "Detected in all" "CAB004606, HPA035799, HPA076570" Approved Approved Vesicles,Cytosol 140000 "Vesicles, Cytosol" "CAB004606: AB_628397, HPA035799: , HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" 1.0 15.8 0.5 0.8 6.0 0.9 0.4 0.0 0.7 0.9 1.1 0.1 0.0 0.8 1.6 2.0 0.7 0.6 2.1 1.5 0.0 1.2 2.9 0.2 1.9 0.3 2.1 0.6 0.3 0.3 0.3 1.1 0.5 28.3 2.2 0.2 3.1 1.2 0.5 0.7 0.2 0.4 1.1 1.2 0.2 1.0 2.4 1.5 0.4 0.3 0.0 0.4 0.7 0.8 0.0 0.0 32.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.6 0.0 6.6 0.0 0.0 0.0 0.0 41.1 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.0 1.1 0.0 0.6 1.2 0.0 0.1 0.0 0.0 0.7 9.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 32.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.0 0.0 0.6 0.0 1.2 2.1 0.6 28.3 1.5 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027070 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Epilepsy, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;thyroid gland: 63.4" "Cell line enhanced" "Detected in some" "AF22: 10.4;HaCaT: 3.7;RPTEC TERT1: 11.6;SH-SY5Y: 13.3" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346" Enhanced Approved Cytosol 13000000 Cytosol "CAB010346: AB_2155274, HPA007637: AB_1080385" "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 19.8 2.7 66.1 2.0 56.7 1.2 33.2 15.1 133.8 6.4 4.4 27.4 0.0 1.4 3.0 3.3 5.6 3.7 18.7 5.8 61.0 30.7 12.5 2.1 6.3 2.7 32.4 41.4 6.6 18.9 1.6 3.0 2.1 34.1 3.8 3.1 2.0 8.6 11.9 2.0 7.2 1.6 3.0 22.1 6.5 1.4 2.4 34.1 0.0 63.4 2.6 3.4 3.5 3.8 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.6 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.6 0.8 0.9 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 66.1 56.7 15.1 45.6 61.0 30.7 32.4 41.4 34.1 34.1 NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256768 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.8" "Cell line enriched" "Detected in some" 8 "U-138 MG: 47.4" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli" 11000000 Nucleoli "Nuclear membrane" "CAB009233: AB_632555, HPA027484: , HPA048065: " "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" 20.8 7.4 22.0 2.5 28.1 1.5 6.2 30.4 41.8 7.0 4.0 8.4 1.3 2.0 12.4 6.7 3.4 9.5 3.9 5.5 22.0 11.1 5.1 2.0 5.7 3.1 11.2 18.7 5.1 2.9 1.6 7.9 2.8 14.7 6.8 4.7 8.0 11.5 8.7 1.9 2.9 2.5 7.7 13.7 4.1 3.0 13.8 13.7 0.0 2.5 0.7 4.3 7.1 4.8 0.7 0.4 1.3 0.5 0.5 0.8 0.0 0.0 5.9 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 0.9 0.0 0.5 0.0 0.0 0.0 1.4 0.0 0.1 1.2 0.5 0.4 0.3 0.1 0.2 0.4 0.3 0.3 0.1 0.7 0.4 0.4 1.3 0.5 0.1 0.4 0.8 0.0 22.0 28.1 30.4 28.9 22.0 11.1 11.2 18.7 14.7 13.7 NUAK1 "ARK5, KIAA0537, NuaK1" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063340-106140033 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;parathyroid gland: 18.6" "Cell line enhanced" "Detected in many" "AF22: 23.0;EFO-21: 23.0;Karpas-707: 16.8;RH-30: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057143 Approved "Nucleoplasm,Nucleoli fibrillar center,Microtubules" "Nucleoli fibrillar center" "Nucleoplasm, Microtubules" "HPA057143: " "unprognostic (4.20e-2)" "unprognostic (8.42e-2)" "unprognostic (3.71e-2)" "prognostic unfavourable (9.83e-4)" "unprognostic (4.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (4.80e-2)" "unprognostic (9.91e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-3)" "prognostic unfavourable (4.27e-4)" "unprognostic (2.31e-1)" "unprognostic (8.70e-2)" "unprognostic (4.47e-2)" 8.2 1.8 4.2 2.0 13.0 0.0 5.5 9.9 20.1 4.6 1.7 24.3 1.1 1.0 5.8 1.6 1.9 3.6 2.7 11.3 5.1 3.3 2.5 2.4 4.9 1.5 8.7 8.4 3.2 1.2 18.6 1.9 2.5 7.6 3.6 2.2 2.3 1.8 3.7 9.4 11.6 1.5 6.3 5.5 1.1 1.5 1.3 9.3 1.1 1.8 1.1 1.4 3.4 3.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.9 3.4 23.0 0.2 9.2 1.0 10.6 5.7 3.9 4.4 3.3 1.7 0.8 0.0 23.0 10.3 4.8 4.8 4.6 2.0 0.0 1.3 0.0 3.6 1.8 1.9 0.0 0.0 4.7 3.1 2.5 0.8 8.3 0.0 16.8 3.1 0.5 0.1 0.2 4.5 1.4 0.0 33.0 4.0 2.5 5.9 2.7 0.1 2.6 0.7 0.2 1.2 0.1 6.2 3.8 12.8 1.4 6.8 0.0 0.0 0.3 1.1 0.0 3.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.2 13.0 9.9 17.5 5.1 3.3 8.7 8.4 7.6 9.3 NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302059-205321791 "Enzymes, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 42.4" "Cell line enhanced" "Detected in many" "BEWO: 24.3;CACO-2: 12.9;RPMI-8226: 18.7;RPTEC TERT1: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in all" "neutrophil: 42.4" "Group enriched" "Detected in all" 4 "B-cells: 15.3;granulocytes: 42.4;T-cells: 10.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA008958 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavourable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favourable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" 1.4 2.8 0.8 12.5 2.4 8.3 0.9 9.2 1.5 18.9 10.4 3.9 2.4 13.6 2.7 3.8 31.3 3.4 1.3 1.1 1.7 1.0 14.5 3.6 16.2 20.3 5.5 1.5 3.3 13.2 0.1 2.3 7.2 2.0 1.5 7.5 9.8 9.7 2.0 0.7 12.9 15.4 0.9 2.7 10.4 2.0 5.6 2.4 5.5 14.5 20.1 31.7 2.8 24.6 15.3 3.6 42.4 5.6 5.7 10.7 5.4 2.2 12.3 7.5 0.3 0.2 0.3 24.3 2.9 3.0 8.1 3.3 12.9 0.4 3.7 1.8 0.8 4.5 1.7 4.4 3.5 0.0 0.2 0.0 0.7 2.2 5.2 0.0 0.0 1.4 3.3 4.7 2.8 0.3 0.5 0.9 1.5 0.5 0.0 0.0 4.8 0.4 0.0 0.5 18.7 22.2 0.0 1.1 0.1 0.8 3.5 0.3 3.6 0.0 0.9 2.9 1.4 0.3 4.6 6.6 1.0 2.3 0.4 0.0 1.1 3.4 5.6 13.2 3.9 4.2 2.8 14.2 4.8 4.6 3.6 15.3 10.7 8.1 42.4 5.7 4.1 1.4 2.8 5.4 0.8 2.4 9.2 1.5 1.7 1.0 5.5 1.5 2.0 2.4 NUDT1 MTH1 ENSG00000106268 "Nudix hydrolase 1" P36639 7 2242222-2251146 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 59.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012636 Approved Supported Cytosol Cytosol "HPA012636: AB_1854696" "unprognostic (1.31e-1)" "unprognostic (1.19e-2)" "unprognostic (2.13e-2)" "unprognostic (2.37e-1)" "unprognostic (3.01e-3)" "unprognostic (3.37e-1)" "prognostic unfavourable (4.44e-4)" "unprognostic (2.15e-2)" "unprognostic (4.77e-1)" "unprognostic (3.81e-2)" "unprognostic (3.81e-2)" "unprognostic (1.53e-1)" "prognostic unfavourable (1.30e-7)" "unprognostic (1.29e-1)" "unprognostic (6.71e-2)" "unprognostic (3.49e-2)" "unprognostic (1.70e-1)" 8.8 3.9 7.4 12.6 13.4 37.1 10.8 5.0 10.8 5.9 9.0 8.7 2.2 9.1 8.2 9.2 13.1 6.0 8.1 11.3 8.7 4.7 4.1 2.9 7.2 18.9 8.2 7.0 4.8 4.0 0.7 1.8 5.8 7.2 7.2 6.3 4.0 5.5 4.2 12.0 18.8 9.3 10.5 11.9 11.1 5.5 26.7 5.3 30.7 4.1 14.4 17.2 6.8 8.1 18.3 59.5 11.9 21.3 10.1 20.4 13.0 21.5 34.8 19.1 25.3 7.0 9.7 14.0 9.5 8.3 13.1 15.3 18.7 16.3 22.8 7.8 10.4 26.4 14.5 14.5 7.7 10.1 24.7 17.8 29.3 15.8 1.7 13.8 18.0 6.4 3.8 18.9 6.7 7.0 14.0 25.5 14.5 55.0 25.7 53.8 41.0 21.5 35.9 28.4 19.1 7.1 12.2 19.2 26.6 9.8 28.9 4.4 19.1 36.7 6.5 12.6 48.1 29.0 22.6 19.7 14.9 23.6 12.7 34.4 45.2 9.0 17.5 11.9 12.9 21.3 10.2 18.3 15.1 13.6 26.6 18.0 15.1 13.1 4.6 10.1 17.4 59.5 20.4 13.0 7.4 13.4 5.0 10.8 8.7 4.7 8.2 7.0 7.2 5.3 NUDT10 "DIPP3a, hDIPP3alpha" ENSG00000122824 "Nudix hydrolase 10" Q8NFP7 X 51332231-51337525 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 28.8;seminal vesicle: 36.3;testis: 27.2" "Cell line enhanced" "Detected in some" "AF22: 6.1;HAP1: 11.4;HEK 293: 8.4;NTERA-2: 20.9;SH-SY5Y: 4.6;U-2 OS: 10.5" "Group enriched" "Detected in many" 6 "glioma: 5.0;prostate cancer: 5.4;testis cancer: 7.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 2.1" "Low lineage specificity" "Detected in many" "HPA047027, HPA057684" Approved Approved Cytosol Cytosol "HPA047027: , HPA057684: " "unprognostic (2.61e-2)" "unprognostic (1.12e-2)" "unprognostic (7.40e-3)" "unprognostic (7.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.54e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.51e-3)" "unprognostic (1.80e-3)" "unprognostic (1.04e-2)" "unprognostic (1.12e-2)" "unprognostic (5.04e-5)" 1.0 2.3 9.3 1.4 10.7 1.8 1.4 6.0 13.1 4.4 2.0 0.9 28.8 1.1 5.5 18.3 1.7 3.4 2.0 0.9 4.9 13.6 3.1 1.9 0.7 0.9 5.3 8.0 19.2 0.6 0.5 4.5 0.5 6.2 17.9 1.3 0.8 1.0 36.3 0.5 1.0 1.2 4.9 1.9 3.1 1.1 27.2 1.2 0.0 0.8 0.0 0.9 2.8 2.9 0.8 0.1 0.0 0.7 2.1 1.0 0.3 0.0 0.0 6.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 11.4 0.5 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 20.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.1 0.0 0.8 1.0 0.0 0.1 0.3 0.0 0.6 0.0 2.1 0.5 0.0 0.0 0.3 9.3 10.7 6.0 11.7 4.9 13.6 5.3 8.0 6.2 1.2 NUDT11 "DIPP3b, FLJ10628, hDIPP3beta" ENSG00000196368 "Nudix hydrolase 11" Q96G61 X 51490011-51496596 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;testis: 35.5" "Cell line enhanced" "Detected in many" "HAP1: 33.1;NTERA-2: 20.6" "Cancer enhanced" "Detected in many" "testis cancer: 17.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 3.7;MAIT T-cell: 1.4;memory CD4 T-cell: 1.2;memory CD8 T-cell: 1.9;naive CD8 T-cell: 3.1;NK-cell: 1.9" "Group enriched" "Detected in many" 5 "NK-cells: 1.9;T-cells: 3.7" "HPA047027, HPA057684" Approved Approved Cytosol Cytosol "HPA047027: , HPA057684: " "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (8.21e-2)" "unprognostic (1.93e-3)" "unprognostic (6.61e-2)" "unprognostic (1.13e-3)" "unprognostic (5.52e-3)" "unprognostic (1.25e-1)" "unprognostic (2.25e-2)" "unprognostic (2.18e-1)" "unprognostic (8.41e-2)" "unprognostic (1.33e-1)" "unprognostic (7.80e-12)" "unprognostic (4.34e-4)" "unprognostic (1.17e-2)" "unprognostic (2.78e-1)" "unprognostic (3.94e-4)" 1.2 5.4 11.2 1.4 21.9 1.6 2.8 7.4 26.1 3.8 2.6 0.8 4.4 1.7 5.9 4.3 1.9 1.6 2.2 0.8 7.0 17.9 0.9 0.6 0.8 1.1 5.3 12.7 10.0 3.8 0.5 2.8 0.6 5.3 10.1 1.4 0.5 1.3 11.9 0.6 1.7 1.5 5.0 1.8 0.9 0.9 35.5 1.1 3.6 1.0 0.2 1.1 1.7 1.6 0.5 0.4 0.0 0.2 1.9 3.7 1.0 0.0 0.5 10.0 0.0 8.6 11.0 0.0 4.6 1.3 0.2 0.2 0.0 0.0 0.0 0.2 5.6 0.7 33.1 11.3 0.1 0.0 2.2 0.0 0.0 0.0 4.1 0.0 2.2 6.7 4.5 3.0 11.0 7.8 0.0 0.0 9.3 0.2 12.5 0.0 20.6 8.4 0.0 7.0 0.0 2.0 0.0 0.0 6.5 2.0 0.0 1.8 0.0 0.0 4.5 2.3 10.9 0.6 0.0 4.3 2.0 7.0 1.5 0.0 0.9 0.0 0.0 0.0 3.7 0.0 1.4 0.5 1.2 1.9 0.4 0.3 0.2 3.1 0.0 1.9 0.2 0.2 0.0 1.0 11.2 21.9 7.4 14.9 7.0 17.9 5.3 12.7 5.3 1.1 NUDT12 DKFZP761I172 ENSG00000112874 "Nudix hydrolase 12" Q9BQG2 5 103548855-103562793 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045449 Supported "HPA045449: " "unprognostic (1.94e-1)" "unprognostic (1.94e-2)" "unprognostic (3.27e-2)" "unprognostic (1.44e-1)" "unprognostic (7.53e-2)" "unprognostic (1.10e-1)" "unprognostic (2.61e-1)" "unprognostic (8.79e-2)" "unprognostic (9.16e-2)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (1.92e-1)" "prognostic favourable (2.86e-5)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (2.67e-1)" "unprognostic (5.92e-2)" 6.3 15.2 10.1 3.5 13.3 0.9 11.4 6.1 12.5 9.2 11.9 10.2 10.9 15.3 6.1 11.7 10.1 8.1 7.7 9.2 10.0 8.9 24.7 25.3 6.1 2.4 13.1 8.5 6.6 15.3 26.9 14.7 6.8 13.7 13.9 13.4 8.4 11.2 7.9 12.1 8.2 15.8 8.7 14.8 4.3 12.5 5.9 14.8 5.0 15.0 8.7 3.4 8.9 6.0 1.5 3.9 0.0 1.3 1.5 2.2 0.9 4.0 1.8 10.0 3.7 6.8 14.4 0.0 7.2 6.9 6.5 8.4 3.5 14.8 0.0 4.8 4.1 6.6 9.3 14.9 9.2 0.0 5.6 4.2 7.0 1.8 7.1 0.0 0.0 6.8 13.2 4.3 11.3 4.4 6.7 0.0 11.4 7.5 0.3 0.2 5.1 5.7 0.0 8.8 3.3 11.0 7.1 7.6 7.9 4.6 7.0 11.0 15.3 4.2 5.3 8.3 3.0 7.2 5.7 4.9 7.5 0.0 8.5 0.0 6.0 0.0 0.9 0.0 0.0 1.3 0.0 0.9 0.8 0.5 2.8 1.5 2.2 1.0 0.0 1.5 0.9 3.9 0.6 0.9 10.1 13.3 6.1 12.5 10.0 8.9 13.1 8.5 13.7 14.8 NUDT14 UGPP ENSG00000183828 "Nudix hydrolase 14" O95848 14 105172938-105181323 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046755, HPA058759" Approved Approved Nucleoli,Microtubules Microtubules Nucleoli "HPA046755: AB_10963433, HPA058759: " "unprognostic (1.05e-2)" "unprognostic (6.01e-2)" "unprognostic (1.89e-1)" "unprognostic (2.44e-1)" "unprognostic (1.91e-1)" "unprognostic (3.55e-1)" "unprognostic (1.05e-3)" "unprognostic (9.17e-3)" "unprognostic (2.02e-1)" "prognostic favourable (1.66e-4)" "unprognostic (3.16e-3)" "unprognostic (3.13e-1)" "prognostic favourable (1.18e-5)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (7.21e-3)" "unprognostic (2.38e-1)" 18.2 12.6 22.4 5.0 16.0 3.1 14.3 2.5 23.4 6.5 11.0 7.9 5.9 16.7 4.7 11.7 7.1 12.6 9.8 20.9 15.4 13.5 16.7 11.2 12.6 9.4 16.1 14.8 4.0 26.0 4.7 27.6 4.8 11.2 10.5 4.6 14.7 16.7 9.9 28.7 6.2 13.8 3.1 13.2 6.3 12.7 8.9 7.8 3.1 17.9 9.2 5.7 4.9 4.7 5.8 15.1 1.7 27.3 6.1 5.8 8.9 8.2 11.3 1.0 4.4 1.3 1.6 18.1 2.3 3.1 3.8 5.5 8.0 8.8 0.6 11.6 1.2 10.4 0.5 6.3 0.3 4.3 8.3 1.8 4.9 5.5 9.7 2.2 22.3 2.3 8.0 0.9 0.7 7.5 2.8 1.4 1.3 24.0 0.2 0.0 5.9 15.8 4.3 10.4 4.8 4.1 23.8 15.7 2.3 4.1 0.1 9.6 8.9 10.7 17.6 6.4 2.8 4.5 2.3 0.7 0.4 1.0 9.3 2.5 2.3 1.7 18.5 0.5 5.8 17.4 3.6 5.8 4.6 3.8 15.1 4.0 4.5 5.2 0.6 6.1 27.3 7.3 2.5 8.9 22.4 16.0 2.5 23.4 15.4 13.5 16.1 14.8 11.2 7.8 NUDT15 "FLJ10956, MTH2" ENSG00000136159 "Nudix hydrolase 15" Q9NV35 13 48037567-48047222 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA038968, HPA038969" Approved Supported Nucleoplasm Nucleoplasm "HPA038968: AB_10697402, HPA038969: " "unprognostic (9.48e-2)" "unprognostic (5.91e-3)" "unprognostic (2.64e-2)" "unprognostic (9.00e-3)" "unprognostic (4.99e-2)" "unprognostic (2.50e-3)" "unprognostic (2.29e-2)" "unprognostic (7.47e-3)" "prognostic unfavourable (1.25e-5)" "unprognostic (1.04e-1)" "unprognostic (8.50e-2)" "unprognostic (3.69e-1)" "unprognostic (4.63e-2)" "unprognostic (1.84e-3)" "unprognostic (3.35e-1)" "unprognostic (9.58e-2)" "unprognostic (8.93e-3)" 15.0 15.2 11.4 16.6 14.6 16.5 18.0 14.1 17.7 14.8 21.1 9.5 14.3 22.1 11.1 15.5 23.8 12.8 13.5 13.3 10.5 15.7 20.3 21.3 11.1 7.4 12.8 11.1 13.0 13.8 6.1 18.6 14.2 15.8 16.9 24.1 8.2 14.1 12.6 15.9 10.8 20.5 11.3 11.9 9.6 13.9 22.2 10.6 11.6 22.3 24.1 12.0 12.1 14.2 4.7 7.0 4.6 9.9 3.8 9.2 4.1 19.7 12.0 22.6 10.0 9.3 13.5 16.7 16.1 15.3 17.9 17.3 17.7 19.3 14.7 9.2 12.7 23.4 21.8 23.7 27.6 7.6 18.9 14.3 11.8 19.2 8.7 21.4 13.7 9.2 15.2 14.4 20.3 19.2 12.6 5.9 28.6 9.7 16.8 20.3 36.2 14.3 11.6 14.6 9.6 19.9 15.1 13.8 14.6 11.0 19.0 12.5 9.7 16.2 9.9 12.6 15.3 15.7 22.2 3.2 5.1 18.4 6.5 16.8 20.3 2.1 7.3 4.6 4.6 9.9 4.5 4.7 7.4 5.8 7.0 4.7 8.8 9.2 1.6 3.8 6.7 5.6 5.0 4.1 11.4 14.6 14.1 17.7 10.5 15.7 12.8 11.1 15.8 10.6 NUDT16 FLJ31265 ENSG00000198585 "Nudix hydrolase 16" Q96DE0 3 131381671-131388830 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 18.2;eosinophil: 18.8;intermediate monocyte: 21.9;myeloid DC: 13.6;neutrophil: 14.6;non-classical monocyte: 24.5" "Group enriched" "Detected in all" 4 "dendritic cells: 13.6;granulocytes: 18.8;monocytes: 24.5" "Low region specificity" "Detected in all" "HPA060452, HPA062492" Uncertain Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA060452: , HPA062492: " "unprognostic (4.85e-3)" "prognostic favourable (9.39e-5)" "unprognostic (3.19e-3)" "unprognostic (9.21e-2)" "unprognostic (2.49e-1)" "unprognostic (1.22e-2)" "unprognostic (9.96e-2)" "unprognostic (1.15e-1)" "unprognostic (5.16e-2)" "unprognostic (1.94e-1)" "unprognostic (1.77e-1)" "unprognostic (5.88e-2)" "prognostic favourable (1.05e-7)" "unprognostic (3.29e-1)" "unprognostic (1.62e-1)" "unprognostic (2.00e-2)" "unprognostic (9.44e-2)" 25.9 13.4 22.1 13.1 22.0 8.7 13.1 13.5 20.5 11.1 32.8 23.9 13.9 20.2 11.7 11.6 8.7 14.0 13.6 22.2 21.1 19.6 25.9 23.1 16.2 31.1 27.7 16.9 23.0 18.3 32.9 9.7 7.6 20.1 13.4 18.4 13.6 11.7 13.6 20.3 6.8 37.5 18.5 30.4 22.2 13.8 9.5 21.6 2.2 17.1 11.5 9.1 12.4 8.4 4.3 13.6 18.8 24.5 3.7 4.3 6.7 12.7 6.8 11.2 5.8 22.6 20.5 5.2 10.4 9.6 7.0 7.3 10.4 5.7 2.1 9.1 9.6 9.3 9.9 6.5 11.3 6.3 7.2 5.4 8.7 10.0 14.5 9.1 9.9 18.3 5.8 4.6 12.7 10.9 6.1 11.1 6.8 13.2 0.0 2.4 8.7 10.1 7.1 8.1 16.0 7.0 10.3 5.5 9.7 6.2 6.3 9.5 13.8 7.2 10.7 11.5 5.0 21.0 8.0 11.0 10.8 0.3 7.4 7.0 6.3 2.2 18.2 18.8 2.6 21.9 2.7 4.3 2.7 2.4 13.6 4.2 2.4 2.4 14.6 3.7 24.5 1.8 4.3 6.7 22.1 22.0 13.5 20.5 21.1 19.6 27.7 16.9 20.1 21.6 NUDT18 "FLJ22494, MTH3" ENSG00000275074 "Nudix hydrolase 18" Q6ZVK8 8 22106872-22109419 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028581, HPA030125" Approved Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA028581: AB_10601381, HPA030125: " "unprognostic (9.90e-3)" "prognostic favourable (1.43e-4)" "unprognostic (4.88e-3)" "prognostic favourable (2.49e-6)" "unprognostic (1.29e-2)" "unprognostic (6.82e-3)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (5.30e-2)" "unprognostic (1.67e-1)" "prognostic favourable (2.47e-4)" "unprognostic (1.43e-1)" "prognostic favourable (8.30e-4)" "unprognostic (3.59e-3)" "unprognostic (1.05e-1)" "unprognostic (6.84e-2)" "unprognostic (2.32e-1)" 3.6 2.7 2.9 4.4 6.4 2.9 3.6 5.3 6.8 2.0 6.1 4.3 5.4 5.3 1.6 11.9 3.7 4.3 3.8 2.5 1.7 2.9 2.9 4.5 6.3 3.2 3.3 1.2 8.6 2.1 5.2 1.8 3.7 3.6 3.8 3.8 5.6 11.0 1.0 3.6 5.4 2.7 2.5 6.0 5.6 2.8 3.4 7.1 5.0 2.3 5.8 3.2 0.0 3.6 3.6 5.0 3.2 7.8 4.7 1.5 6.9 14.8 0.5 3.2 11.8 4.4 8.1 4.1 11.4 5.6 6.4 3.5 5.6 5.2 6.7 5.0 12.2 2.1 6.9 1.9 6.4 2.0 4.4 4.2 3.4 7.7 1.3 13.8 8.0 6.5 2.3 5.8 7.0 3.2 8.8 5.3 7.3 5.8 3.9 0.8 3.6 2.6 1.3 5.6 8.1 6.1 1.6 2.5 3.0 3.6 3.6 8.4 7.4 5.6 3.6 2.0 4.8 2.1 3.9 0.4 1.7 6.3 4.0 8.8 0.1 2.9 5.0 4.7 3.2 4.3 2.6 3.7 2.7 2.0 3.6 4.0 2.2 0.7 7.8 2.3 3.6 1.4 1.5 NUDT2 APAH1 ENSG00000164978 "Nudix hydrolase 2" P50583 9 34329506-34343713 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004684, HPA044903, HPA058623, HPA067639" Uncertain Enhanced Nucleoplasm Nucleoplasm "CAB004684: AB_425306, HPA044903: , HPA058623: , HPA067639: " "unprognostic (2.74e-3)" "unprognostic (2.58e-2)" "unprognostic (3.37e-1)" "unprognostic (2.05e-3)" "unprognostic (3.08e-1)" "unprognostic (2.39e-1)" "unprognostic (1.24e-1)" "unprognostic (6.55e-2)" "unprognostic (7.06e-2)" "unprognostic (3.05e-3)" "unprognostic (1.18e-2)" "unprognostic (2.80e-1)" "unprognostic (2.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.72e-1)" "unprognostic (1.23e-1)" "unprognostic (1.91e-1)" 12.0 18.0 21.6 9.6 21.9 10.2 20.6 14.0 25.5 14.9 14.9 26.0 15.4 12.8 15.7 30.2 14.5 20.5 12.3 16.0 17.3 18.6 10.7 17.5 11.2 12.2 19.5 19.0 28.3 20.9 12.0 19.0 14.1 20.5 16.5 15.3 15.7 16.1 13.0 30.8 13.9 10.1 14.7 20.7 11.3 13.0 8.6 19.1 18.6 3.8 13.2 13.8 14.4 12.1 16.6 15.8 14.3 12.2 14.3 22.2 11.2 23.6 9.8 12.7 4.5 8.8 16.2 9.2 11.4 25.9 13.3 13.9 6.7 11.2 6.6 9.5 14.2 10.4 11.5 28.2 13.5 24.6 10.3 14.2 18.4 12.5 25.4 10.9 5.8 16.3 18.2 17.1 32.2 27.3 4.0 26.9 19.3 14.7 11.3 10.3 7.8 28.1 14.7 7.9 16.6 13.0 7.7 2.6 10.4 18.5 7.0 10.7 5.7 11.8 17.6 11.5 10.3 7.5 11.9 6.1 9.8 11.6 14.3 10.5 14.2 14.3 12.2 9.7 11.7 10.3 16.7 16.6 19.2 15.2 15.8 15.0 22.2 19.6 4.5 14.3 10.7 14.7 19.7 11.2 21.6 21.9 14.0 25.5 17.3 18.6 19.5 19.0 20.5 19.1 NUDT22 MGC13045 ENSG00000149761 "Nudix hydrolase 22" Q9BRQ3 11 64225941-64230686 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039334, HPA053464" Approved Enhanced Nucleoplasm Nucleoplasm "HPA039334: AB_10795174, HPA053464: " "unprognostic (2.72e-1)" "unprognostic (3.77e-1)" "unprognostic (1.86e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-2)" "unprognostic (9.75e-2)" "unprognostic (1.73e-3)" "unprognostic (1.98e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-1)" "unprognostic (7.65e-2)" "unprognostic (6.61e-2)" "prognostic favourable (2.18e-6)" "unprognostic (1.76e-2)" "unprognostic (1.50e-1)" "unprognostic (1.71e-1)" "unprognostic (8.54e-2)" 9.2 16.8 8.1 16.0 9.2 14.3 9.8 7.3 12.8 9.2 24.2 9.1 30.9 29.6 9.1 16.9 17.8 9.0 16.7 23.4 8.3 7.0 21.1 30.1 10.2 15.9 10.5 8.4 7.9 26.4 13.8 12.2 14.7 8.6 12.3 8.5 9.0 28.6 35.2 24.9 12.9 23.7 11.4 7.8 20.5 18.5 7.8 7.7 19.5 15.4 15.7 19.6 13.5 9.4 30.0 49.1 20.0 33.9 19.2 25.0 20.1 14.5 9.3 2.3 9.7 3.6 4.4 8.9 6.1 6.4 4.4 4.1 6.0 12.4 6.9 16.3 6.1 15.2 1.4 9.7 0.6 8.8 3.9 9.3 6.8 6.3 10.7 6.0 15.4 6.7 7.3 4.7 5.0 7.2 4.5 7.6 5.2 21.8 8.3 11.1 3.7 19.7 10.2 3.9 25.6 7.7 8.1 5.4 8.6 5.4 20.6 24.5 21.0 6.8 6.7 7.5 7.1 23.5 5.2 28.5 11.3 4.3 25.7 7.0 8.7 13.8 28.7 20.0 23.0 33.9 20.5 25.3 20.3 22.4 29.1 30.0 18.0 19.6 17.3 19.2 31.8 49.1 25.0 20.1 8.1 9.2 7.3 12.8 8.3 7.0 10.5 8.4 8.6 7.7 NUDT3 DIPP ENSG00000272325 "Nudix hydrolase 3" O95989 6 34279679-34392674 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047027, HPA055953" Uncertain Approved Cytosol 110000 Cytosol "HPA047027: , HPA055953: " "unprognostic (2.42e-1)" "prognostic favourable (5.29e-4)" "unprognostic (9.63e-3)" "unprognostic (4.74e-3)" "unprognostic (3.60e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-3)" "unprognostic (4.21e-2)" "unprognostic (4.93e-3)" "unprognostic (1.08e-1)" "unprognostic (3.16e-1)" "unprognostic (4.63e-1)" "unprognostic (1.24e-2)" "unprognostic (3.28e-2)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (6.24e-2)" 10.5 11.4 38.8 9.3 28.6 8.8 12.6 33.4 40.0 15.4 11.4 16.8 10.3 7.7 11.4 25.9 10.8 15.2 8.5 16.9 33.8 30.0 15.3 10.1 11.2 10.5 29.4 25.6 17.4 9.1 27.9 9.3 8.9 26.1 11.4 9.7 11.2 9.4 15.6 50.7 11.2 8.0 11.2 20.3 13.0 8.4 7.3 21.3 5.4 21.3 8.7 12.1 8.6 9.9 4.5 6.4 12.4 5.9 2.1 3.9 2.6 5.4 4.0 10.7 21.0 7.2 12.2 4.7 3.9 6.7 4.1 3.0 4.8 3.8 19.5 5.4 7.1 4.6 6.1 10.7 7.7 7.2 7.7 21.5 5.6 10.3 7.1 20.2 11.2 10.9 10.0 5.0 9.4 11.8 21.3 7.1 6.6 5.7 14.0 23.7 6.9 4.0 12.2 8.9 20.3 9.4 11.4 15.2 16.9 8.8 12.5 15.9 12.5 14.5 12.9 8.3 3.0 7.2 8.6 6.1 14.0 14.3 5.0 20.7 12.9 1.9 5.8 12.4 3.4 5.9 3.9 3.4 3.4 3.2 6.4 4.5 3.2 3.7 4.1 2.1 5.8 3.2 2.4 2.6 38.8 28.6 33.4 40.0 33.8 30.0 29.4 25.6 26.1 21.3 NUDT4 "DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, KIAA0487" ENSG00000173598 "Nudix hydrolase 4" Q9NZJ9 12 93377883-93408146 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 140.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA017593, HPA047027, HPA057684" Approved Approved Cytosol Cytosol "HPA017593: AB_1854703, HPA047027: , HPA057684: " "unprognostic (1.44e-2)" "unprognostic (2.15e-1)" "unprognostic (4.40e-3)" "unprognostic (4.25e-1)" "unprognostic (3.08e-3)" "unprognostic (1.42e-1)" "unprognostic (8.12e-2)" "unprognostic (9.09e-3)" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (2.60e-2)" "unprognostic (1.96e-1)" "prognostic favourable (1.27e-4)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (5.01e-1)" "unprognostic (8.32e-3)" 17.2 29.7 14.1 14.7 9.5 37.4 20.4 7.0 29.0 15.2 14.7 6.7 17.5 6.5 13.6 24.8 13.7 12.8 40.0 140.7 12.4 12.4 47.9 11.2 11.3 10.9 9.4 13.7 41.9 21.1 16.1 11.9 19.2 13.9 27.1 16.9 25.1 65.2 14.8 40.3 8.1 12.7 13.8 12.6 9.2 13.1 10.6 6.3 14.6 25.5 22.4 8.9 19.6 32.9 6.0 4.1 13.6 3.6 7.6 6.6 2.5 5.8 5.1 9.2 10.3 34.3 14.2 11.6 16.4 13.1 9.4 7.0 47.4 14.7 8.2 3.6 13.1 7.4 25.8 8.3 14.5 12.6 5.4 30.9 4.4 24.1 33.1 16.1 7.5 30.8 27.8 9.7 21.8 53.6 31.4 11.6 10.8 6.0 14.9 15.4 14.5 12.1 12.6 8.2 8.9 11.4 42.7 7.4 9.6 13.3 26.2 36.9 19.0 21.0 20.3 8.1 4.7 12.1 10.4 6.5 8.1 12.2 4.2 12.7 24.7 8.2 2.8 13.6 3.9 3.6 6.6 6.0 5.8 3.9 2.6 4.7 6.2 5.8 2.4 7.6 2.9 4.1 5.2 2.5 14.1 9.5 7.0 29.0 12.4 12.4 9.4 13.7 13.9 6.3 NUDT5 "hYSAH1, YSA1H" ENSG00000165609 "Nudix hydrolase 5" Q9UKK9 10 12165325-12196144 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019827 Approved Approved Nucleoplasm,Vesicles,Centrosome 660000 Vesicles "Nucleoplasm, Centrosome" "HPA019827: AB_1854704" "unprognostic (2.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.77e-3)" "unprognostic (4.91e-2)" "unprognostic (2.54e-2)" "unprognostic (4.60e-2)" "unprognostic (1.32e-1)" "unprognostic (6.39e-3)" "unprognostic (2.06e-1)" "unprognostic (9.97e-2)" "prognostic unfavourable (7.14e-12)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (3.12e-2)" "unprognostic (3.68e-2)" 19.6 22.0 17.4 18.6 21.2 13.5 20.2 15.4 21.4 16.7 20.4 16.1 15.2 17.3 10.0 16.5 25.8 16.3 12.1 10.0 16.2 14.3 26.0 57.1 16.8 22.7 21.7 12.8 12.5 16.9 19.1 35.7 19.9 18.5 13.4 24.2 13.2 16.7 19.7 5.1 20.6 15.9 11.6 17.9 22.4 14.1 8.0 21.5 28.2 19.1 16.5 29.5 16.2 18.6 22.4 45.9 50.1 19.5 16.2 37.0 20.4 37.3 27.6 33.0 30.7 32.0 31.6 29.3 27.7 17.7 32.7 35.1 39.6 35.7 37.4 24.1 22.4 37.6 46.0 42.9 30.0 30.6 45.0 31.1 33.9 58.1 33.4 20.6 21.9 33.2 25.6 35.6 18.2 41.6 41.6 25.6 29.7 34.3 38.6 24.2 28.7 17.2 35.3 12.0 43.4 30.5 12.9 15.9 23.9 33.6 25.9 38.5 44.4 21.3 26.0 13.9 26.7 38.8 33.8 21.6 37.9 50.3 29.3 26.9 10.3 8.1 19.1 33.5 22.8 19.5 26.2 22.4 24.6 26.8 27.0 18.3 17.0 23.0 50.1 16.2 14.8 45.9 37.0 20.4 17.4 21.2 15.4 21.4 16.2 14.3 21.7 12.8 18.5 21.5 NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422582-87459454 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" 9000 "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: AB_10696790, HPA044866: , HPA078535: " "unprognostic (7.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.45e-2)" "prognostic favourable (7.43e-5)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-2)" "unprognostic (4.23e-1)" "prognostic favourable (8.00e-11)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-3)" 14.2 25.6 19.5 10.0 22.7 4.0 31.1 22.5 22.3 17.9 19.6 11.8 18.0 27.0 17.3 24.5 12.8 16.2 11.4 18.0 21.8 19.4 28.1 30.9 15.8 12.2 22.9 16.5 18.4 64.1 35.4 33.1 17.5 20.0 22.5 18.3 11.3 20.2 18.7 23.8 10.2 30.0 16.0 17.0 9.9 14.1 14.1 22.6 7.6 22.7 16.0 9.7 13.6 35.9 13.9 13.8 3.7 13.9 9.3 18.3 10.6 10.6 11.5 12.8 6.4 25.4 16.0 10.4 20.5 13.3 7.9 7.9 8.1 18.4 15.6 21.0 16.6 7.3 11.8 14.4 12.7 11.7 9.1 5.1 13.4 14.1 16.0 9.3 8.4 15.4 19.2 9.4 8.9 15.8 14.3 10.5 14.9 14.0 13.0 10.1 10.3 4.7 15.3 11.4 9.1 59.7 9.8 15.5 10.6 13.2 23.4 10.4 13.4 13.5 16.2 12.8 12.4 9.3 10.0 8.1 6.3 12.7 18.4 8.8 16.1 0.9 11.7 3.7 13.4 13.8 12.4 13.9 13.4 13.2 13.8 12.0 15.9 18.3 1.3 9.3 13.9 13.0 12.3 10.6 19.5 22.7 22.5 22.3 21.8 19.4 22.9 16.5 20.0 22.6 NUS1 "C6orf68, MGC7199, NgBR, TANGO14" ENSG00000153989 "NUS1 dehydrodolichyl diphosphate synthase subunit" Q96E22 6 117675502-117710640 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Angiogenesis, Differentiation, Lipid metabolism" "Developmental protein, Receptor, Transferase" "Congenital disorder of glycosylation, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027504 Supported Approved "Vesicles,Plasma membrane" Vesicles "Plasma membrane" "HPA027504: AB_10603124" "unprognostic (1.21e-2)" "prognostic unfavourable (6.99e-4)" "unprognostic (1.09e-2)" "unprognostic (2.31e-1)" "unprognostic (1.21e-1)" "unprognostic (8.26e-3)" "unprognostic (1.42e-3)" "unprognostic (2.42e-2)" "unprognostic (8.62e-2)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (8.35e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-1)" "unprognostic (3.22e-2)" "unprognostic (1.56e-1)" "unprognostic (7.97e-2)" 8.4 10.2 14.7 9.3 14.7 7.0 10.0 8.8 13.4 29.6 9.2 6.8 2.0 7.1 9.6 13.5 9.5 8.8 7.1 8.2 12.7 9.9 13.1 17.4 9.5 8.4 16.4 15.7 8.8 28.9 15.0 20.0 10.6 16.2 9.6 9.3 7.1 13.8 14.9 7.9 6.1 14.4 8.5 7.3 9.1 10.6 5.6 12.2 7.2 16.5 3.1 8.7 9.1 18.0 2.4 8.1 3.3 4.9 4.1 4.5 2.3 10.0 7.4 16.1 18.0 16.3 21.4 39.6 18.5 19.3 15.5 17.9 16.8 11.3 23.9 20.1 17.0 9.2 23.9 18.1 28.9 17.9 22.0 27.3 12.5 30.1 25.1 34.4 16.1 18.7 20.6 16.9 34.7 15.9 32.6 21.3 23.1 11.4 16.1 21.9 18.7 13.6 15.6 11.6 17.1 30.7 10.1 19.1 15.1 11.1 14.5 13.6 9.2 36.1 13.9 9.6 11.9 15.3 26.5 29.6 22.1 25.4 22.7 26.5 19.1 3.3 3.0 1.8 3.1 3.0 4.5 2.4 3.7 4.1 3.2 2.1 3.1 4.0 0.2 4.1 4.9 8.1 3.4 2.3 14.7 14.7 8.8 13.4 12.7 9.9 16.4 15.7 16.2 12.2 NXN "FLJ12614, NRX" ENSG00000167693 Nucleoredoxin Q6DKJ4 17 799313-979770 "Enzymes, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 31.2;HHSteC: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA023566 Approved Supported "Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" "HPA023566: AB_1854737" "unprognostic (1.68e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-2)" "unprognostic (3.48e-2)" "unprognostic (7.29e-2)" "unprognostic (1.00e-1)" "unprognostic (1.75e-2)" "unprognostic (6.98e-2)" "unprognostic (1.65e-3)" "unprognostic (2.27e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-1)" "unprognostic (5.76e-2)" "unprognostic (3.56e-2)" "unprognostic (2.34e-1)" "unprognostic (2.68e-2)" "unprognostic (2.05e-3)" 11.9 4.9 5.8 11.5 5.9 1.0 12.8 5.0 5.0 21.7 27.1 4.7 16.9 4.0 21.5 19.2 14.0 13.8 14.5 7.6 6.0 4.2 5.1 3.8 15.8 7.2 3.9 3.1 13.9 23.1 1.1 3.2 10.0 5.6 18.9 3.6 12.3 10.9 19.0 48.9 10.6 8.1 25.8 4.4 2.9 13.0 6.4 4.3 6.0 5.7 17.4 11.8 20.8 26.3 0.9 1.2 1.5 0.2 1.8 1.6 0.3 4.3 6.5 25.7 16.5 1.7 0.3 1.4 13.8 9.1 14.6 23.5 15.4 4.6 0.1 26.5 17.6 31.2 16.5 25.8 11.7 0.2 9.6 0.0 4.1 13.5 34.4 0.1 0.7 10.4 23.9 1.9 11.5 13.1 2.2 0.0 3.8 1.7 0.8 0.3 12.3 0.4 1.9 0.6 0.1 10.3 6.3 6.6 4.3 6.5 0.0 0.3 4.6 3.9 0.0 0.3 6.2 0.1 3.8 2.3 1.5 0.1 0.1 0.5 0.2 0.8 0.2 0.1 0.2 0.1 0.1 0.9 0.4 0.2 1.2 0.3 1.6 0.2 1.5 1.8 0.1 1.2 1.4 0.3 5.8 5.9 5.0 5.0 6.0 4.2 3.9 3.1 5.6 4.3 OAS1 "IFI-4, OIAS, OIASI" ENSG00000089127 "2'-5'-oligoadenylate synthetase 1" P00973 12 112906777-112933222 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 83.9" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 51.4;BJ hTERT+ SV40 Large T+ RasG12V: 73.9;U-266/70: 72.5;U-266/84: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 83.9" "Low lineage specificity" "Detected in all" "HPA003657, CAB021104" Uncertain Supported Nucleoplasm,Cytosol "Intracellular and membrane" "Nucleoplasm, Cytosol" "CAB021104: AB_10057722, HPA003657: AB_1854747" "unprognostic (1.03e-1)" "unprognostic (6.59e-2)" "unprognostic (8.56e-3)" "unprognostic (2.20e-3)" "unprognostic (2.78e-1)" "unprognostic (1.30e-1)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.20e-2)" "prognostic unfavourable (3.02e-4)" "unprognostic (5.37e-2)" "unprognostic (1.63e-2)" "unprognostic (6.91e-2)" "unprognostic (3.68e-2)" "unprognostic (5.67e-2)" "prognostic favourable (6.12e-6)" 31.2 7.3 6.1 16.6 7.1 5.7 8.4 2.1 6.0 16.4 25.4 11.0 2.6 23.6 5.8 21.0 39.1 5.1 10.7 5.1 4.2 5.7 18.3 23.3 20.7 17.3 5.9 5.3 7.4 3.2 4.3 6.1 18.8 8.6 11.5 20.5 11.7 31.8 4.2 2.9 6.3 27.2 7.6 9.4 30.1 22.7 4.2 6.2 21.6 9.4 13.5 27.3 20.9 13.0 18.2 24.4 4.1 83.9 4.5 16.8 29.0 1.0 5.8 0.0 0.0 2.0 1.6 0.4 0.0 7.6 51.4 73.9 3.3 6.2 8.0 2.3 0.0 2.6 0.0 0.7 0.7 5.9 0.0 0.2 10.5 1.3 0.6 0.1 0.4 0.1 2.2 1.9 0.0 2.7 0.0 3.5 0.0 0.1 0.2 3.6 0.3 5.1 1.7 0.0 3.3 2.6 16.6 0.1 0.3 0.8 1.0 19.6 0.2 1.3 10.1 0.0 0.1 0.7 0.1 72.5 55.0 5.5 0.6 2.3 0.4 1.0 40.9 0.5 4.9 63.6 4.6 18.2 6.5 6.1 24.4 13.6 2.5 3.3 4.1 4.5 83.9 22.1 16.8 29.0 6.1 7.1 2.1 6.0 4.2 5.7 5.9 5.3 8.6 6.2 OAS2 ENSG00000111335 "2'-5'-oligoadenylate synthetase 2" P29728 12 112978395-113011723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 70.9;BJ hTERT+ SV40 Large T+ RasG12V: 57.8;SK-MEL-30: 27.7;U-266/70: 25.8;U-266/84: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA003320, CAB024984" Approved Approved Centrosome Centrosome "CAB024984: , HPA003320: " "unprognostic (2.39e-1)" "unprognostic (9.51e-2)" "unprognostic (2.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.34e-1)" "unprognostic (7.94e-2)" "unprognostic (4.79e-2)" "unprognostic (2.05e-2)" "unprognostic (1.31e-1)" "unprognostic (7.64e-3)" "prognostic unfavourable (4.63e-4)" "unprognostic (4.20e-1)" "prognostic unfavourable (4.31e-6)" "unprognostic (1.12e-1)" "unprognostic (4.17e-2)" "unprognostic (1.11e-1)" "unprognostic (1.94e-2)" 37.9 3.8 4.0 13.9 5.1 9.0 7.2 1.8 4.9 8.5 4.3 7.5 1.2 4.6 9.0 6.9 13.2 3.9 9.6 6.9 3.8 4.4 8.8 9.9 15.6 24.1 5.0 3.7 3.9 1.9 1.2 2.9 22.2 7.3 6.6 4.7 6.9 32.9 1.8 2.2 2.9 8.8 6.4 7.1 36.6 9.7 2.2 3.0 32.4 9.8 8.2 27.4 13.7 5.4 12.0 12.7 2.0 26.8 15.1 17.4 13.2 0.7 0.1 0.0 0.0 0.3 2.6 0.0 0.1 8.0 70.9 57.8 0.1 1.2 17.8 1.7 1.5 0.8 0.1 0.2 2.5 4.4 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 1.3 4.0 0.0 1.1 0.0 9.3 0.0 0.3 0.5 1.0 0.0 2.5 3.8 0.0 2.7 0.0 6.3 0.0 0.0 0.7 0.2 27.7 0.6 1.1 1.8 0.1 0.0 0.3 0.0 25.8 22.2 2.8 0.6 0.9 0.6 2.0 15.9 1.2 13.4 26.8 16.8 12.0 15.4 15.2 12.7 8.9 15.2 11.2 1.8 15.1 26.0 5.3 17.4 13.2 4.0 5.1 1.8 4.9 3.8 4.4 5.0 3.7 7.3 3.0 OAS3 ENSG00000111331 "2'-5'-oligoadenylate synthetase 3" Q9Y6K5 12 112938352-112973249 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "BJ hTERT+ SV40 Large T+: 64.0;BJ hTERT+ SV40 Large T+ RasG12V: 70.0;RT4: 17.5;U-266/84: 19.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "HPA041253, HPA041372" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" 21000 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041253: AB_10794990, HPA041372: AB_10795590" "unprognostic (8.47e-2)" "unprognostic (9.13e-2)" "unprognostic (1.27e-2)" "unprognostic (4.39e-3)" "unprognostic (2.59e-2)" "unprognostic (1.45e-1)" "unprognostic (4.14e-3)" "unprognostic (8.06e-3)" "unprognostic (3.19e-1)" "unprognostic (1.73e-2)" "unprognostic (2.29e-3)" "unprognostic (2.48e-1)" "prognostic unfavourable (2.23e-5)" "unprognostic (4.25e-2)" "unprognostic (1.37e-2)" "unprognostic (3.29e-2)" "unprognostic (2.93e-2)" 36.9 4.9 5.1 11.2 5.4 18.3 7.0 2.9 5.5 10.5 6.8 5.5 3.2 7.3 10.0 11.8 17.9 4.2 9.4 6.7 4.5 5.3 10.3 7.1 19.9 13.3 5.1 5.1 6.1 3.2 3.3 4.6 19.3 8.7 5.6 6.9 8.9 24.7 3.4 3.3 6.0 9.3 8.3 6.2 22.0 9.5 3.0 3.3 21.3 9.9 6.7 13.5 9.9 8.2 2.6 4.8 10.1 14.7 5.0 3.8 3.9 6.3 9.5 0.0 1.5 0.3 1.4 0.8 1.2 8.3 64.0 70.0 7.2 5.8 0.4 2.3 2.9 5.4 1.2 7.7 5.4 4.7 0.3 4.9 4.4 2.3 1.2 1.7 2.7 0.5 2.5 9.1 0.5 3.3 0.1 1.0 0.8 4.1 2.7 0.9 0.5 5.5 3.9 3.4 0.1 3.0 17.5 0.2 0.0 5.8 2.2 5.7 7.6 0.5 2.2 1.7 1.2 1.5 2.6 0.5 19.1 0.1 1.4 4.8 5.2 0.9 7.9 1.6 2.0 8.6 2.5 2.6 3.0 3.0 4.8 1.3 2.2 2.6 10.1 5.0 14.7 0.2 3.8 3.9 5.1 5.4 2.9 5.5 4.5 5.3 5.1 5.1 8.7 3.3 OAT HOGA ENSG00000065154 "Ornithine aminotransferase" P04181 10 124397303-124418976 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 208.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033576, HPA040098, HPA064742" Enhanced Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB033576: AB_2298892, HPA040098: AB_10793955, HPA064742: " "unprognostic (1.61e-2)" "unprognostic (1.70e-2)" "unprognostic (9.96e-2)" "unprognostic (1.02e-2)" "unprognostic (1.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.03e-1)" "unprognostic (4.43e-3)" "unprognostic (1.65e-1)" "unprognostic (2.37e-2)" "unprognostic (2.45e-1)" "unprognostic (7.62e-2)" "unprognostic (1.70e-2)" "unprognostic (2.21e-1)" "unprognostic (2.19e-1)" "unprognostic (2.72e-2)" "unprognostic (2.00e-2)" 13.5 37.1 25.9 9.1 26.7 20.3 33.8 17.2 39.8 24.7 71.9 22.8 33.9 164.0 21.6 15.5 26.1 14.9 16.0 12.7 25.6 29.8 25.6 36.8 11.6 9.3 27.9 30.1 21.8 12.3 12.1 18.0 14.8 37.8 17.9 15.8 13.3 55.2 29.1 13.7 16.3 208.5 22.5 25.5 8.4 17.3 14.6 19.4 4.9 15.9 23.1 15.2 15.5 18.2 10.2 26.5 23.0 23.6 9.6 20.1 16.3 41.4 7.5 4.9 17.6 50.3 48.5 16.8 25.1 51.3 22.5 24.7 19.2 5.4 0.0 18.3 42.4 44.2 22.5 47.0 24.5 7.3 31.2 46.4 5.3 14.3 25.9 0.0 30.6 31.7 24.3 20.2 23.6 26.1 79.8 8.9 31.3 10.7 12.2 2.6 9.8 10.6 11.4 18.8 11.2 21.5 0.6 10.3 11.0 15.8 42.1 35.3 14.0 11.4 20.1 12.8 12.0 21.2 15.6 7.6 8.0 11.2 17.7 12.5 6.1 18.6 23.6 20.7 18.5 20.7 20.1 9.6 15.6 19.4 26.5 10.2 19.6 19.1 23.0 9.6 20.8 5.7 14.4 16.3 25.9 26.7 17.2 39.8 25.6 29.8 27.9 30.1 37.8 19.4 OBSCN "ARHGEF30, KIAA1556, KIAA1639, UNC89" ENSG00000154358 "Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF" Q5VST9 1 228208130-228378874 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Calmodulin-binding, Developmental protein, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 180.2;tongue: 48.4" "Cell line enhanced" "Detected in many" "HeLa: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA021186, HPA065801" Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA021186: AB_1854761, HPA065801: " "unprognostic (8.47e-3)" "unprognostic (1.56e-1)" "unprognostic (9.99e-2)" "prognostic unfavourable (1.64e-4)" "unprognostic (5.30e-3)" "unprognostic (6.36e-2)" "unprognostic (4.54e-3)" "unprognostic (1.82e-1)" "unprognostic (8.81e-2)" "unprognostic (1.93e-2)" "unprognostic (3.38e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-2)" 2.5 0.9 0.5 0.9 4.4 0.6 0.7 3.1 0.6 0.6 0.8 0.5 0.5 0.6 0.8 4.4 2.4 1.0 0.6 21.2 0.5 0.7 1.6 0.5 1.0 1.0 0.5 0.5 1.7 1.4 0.4 2.4 0.5 0.9 1.7 0.3 5.2 2.6 1.1 180.2 1.1 0.8 0.5 0.6 1.4 0.5 0.7 0.6 0.5 2.2 48.4 3.5 0.6 0.7 1.0 1.1 0.1 0.4 0.6 3.2 0.7 2.9 2.8 8.0 4.5 0.2 0.1 5.6 1.5 0.5 1.0 0.9 2.0 2.1 5.7 8.1 0.5 1.0 0.4 1.1 0.2 2.1 5.1 1.9 16.0 0.0 2.0 1.3 6.1 3.0 1.0 0.4 0.2 0.4 5.3 1.3 0.3 5.0 2.0 1.6 8.8 1.7 8.1 0.1 1.3 4.6 1.5 3.0 9.0 0.2 2.9 1.1 8.0 3.7 0.7 0.0 9.3 0.2 0.1 4.7 0.9 1.4 0.0 0.8 2.1 0.1 0.4 0.0 0.9 0.1 0.9 0.5 0.9 0.7 0.9 1.0 3.2 0.5 0.1 0.6 0.1 1.1 0.8 0.7 0.5 4.4 3.1 0.6 0.5 0.7 0.5 0.5 0.9 0.6 OCRL OCRL1 ENSG00000122126 "OCRL, inositol polyphosphate-5-phosphatase" Q01968 X 129539849-129592561 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" Hydrolase "Cataract, Ciliopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "non-classical monocyte: 6.6" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;monocytes: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012495 Approved Approved "Microtubules,Centriolar satellite,Cytosol" Cytosol "Microtubules, Centriolar satellite" "HPA012495: AB_1851804" "prognostic unfavourable (2.93e-5)" "unprognostic (3.17e-2)" "unprognostic (2.30e-1)" "unprognostic (6.34e-3)" "unprognostic (9.88e-2)" "unprognostic (1.35e-1)" "unprognostic (2.82e-2)" "unprognostic (2.68e-1)" "unprognostic (3.08e-3)" "unprognostic (2.56e-2)" "unprognostic (6.30e-3)" "unprognostic (1.74e-1)" "unprognostic (4.61e-3)" "unprognostic (4.10e-1)" "unprognostic (5.83e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" 12.1 20.5 10.7 6.0 18.2 5.3 10.8 13.4 23.1 12.7 13.4 10.1 28.8 9.1 15.8 19.7 13.3 12.8 13.8 8.6 13.0 20.5 10.9 11.3 8.6 6.0 12.9 15.1 33.0 12.4 37.3 20.3 13.2 17.8 21.7 14.1 15.3 8.5 27.7 11.4 9.6 9.8 21.5 8.0 6.3 11.4 23.2 6.4 4.3 19.0 5.6 4.1 18.0 9.2 0.4 2.4 0.3 6.6 0.0 0.7 0.7 9.6 11.2 9.2 10.4 16.4 13.6 9.0 14.9 11.9 15.4 14.3 7.5 7.1 0.8 25.7 12.6 6.1 17.0 11.3 16.1 0.0 11.5 3.0 10.1 7.5 12.2 3.0 0.3 11.4 15.0 15.1 15.1 11.4 4.0 7.4 16.0 12.7 2.2 4.2 3.3 16.7 2.2 9.6 5.8 8.8 10.1 11.3 14.3 7.0 10.0 7.8 7.2 5.3 9.6 12.6 5.8 13.1 14.8 2.1 1.6 2.0 8.8 11.1 9.9 0.0 2.1 0.0 0.2 2.4 0.7 0.3 0.1 0.1 2.4 0.4 0.6 0.2 0.3 0.0 6.6 0.9 0.1 0.7 10.7 18.2 13.4 23.1 13.0 20.5 12.9 15.1 17.8 6.4 ODC1 ODC ENSG00000115758 "Ornithine decarboxylase 1" P11926 2 10439968-10448504 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Polyamine biosynthesis" "Decarboxylase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001536, CAB035996" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB035996: , HPA001536: AB_1079521" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (7.25e-3)" "unprognostic (5.21e-3)" "unprognostic (4.22e-2)" "unprognostic (2.70e-1)" "prognostic unfavourable (3.07e-5)" "unprognostic (3.06e-2)" "unprognostic (4.18e-2)" "unprognostic (6.27e-2)" "unprognostic (3.04e-1)" "unprognostic (6.65e-2)" "unprognostic (1.67e-3)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.26e-2)" "unprognostic (5.86e-2)" 13.2 8.2 11.6 33.5 11.1 41.8 9.1 7.2 11.8 11.7 17.4 11.5 33.8 8.6 22.9 21.6 16.5 16.5 30.0 33.8 9.7 10.6 31.5 48.7 14.2 42.3 11.3 6.5 29.2 48.7 13.4 35.4 6.9 11.2 26.3 20.7 18.2 11.0 27.2 64.2 9.6 14.9 26.2 10.2 20.4 19.2 54.6 6.3 31.0 16.4 19.8 39.6 16.1 14.6 13.4 10.8 2.4 2.4 1.2 4.4 3.0 18.6 15.0 20.9 24.7 3.7 11.2 48.5 27.0 13.4 25.6 11.9 79.7 8.7 98.9 13.6 16.5 3.4 63.9 30.7 31.2 37.6 26.7 45.1 25.8 48.6 30.4 76.2 10.8 7.5 8.3 57.9 72.7 20.5 75.0 32.2 14.2 12.3 75.4 30.0 38.1 49.0 53.8 65.7 66.6 15.5 13.7 29.2 24.9 33.9 10.4 13.7 7.0 34.2 14.3 20.8 42.9 26.8 58.0 15.0 45.4 89.9 18.7 50.5 12.8 0.0 1.3 2.4 2.7 2.4 3.2 13.4 3.8 4.4 3.0 11.0 2.7 4.3 0.5 1.2 1.5 10.8 3.8 3.0 11.6 11.1 7.2 11.8 9.7 10.6 11.3 6.5 11.2 6.3 OGDH E1k ENSG00000105953 "Oxoglutarate dehydrogenase" Q02218 7 44606572-44709066 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 99.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019514, HPA020347" Supported Enhanced Mitochondria 53000 Mitochondria "HPA019514: AB_1854772, HPA020347: AB_1854773" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (4.39e-1)" "unprognostic (5.64e-3)" "unprognostic (3.02e-3)" "unprognostic (1.20e-1)" "unprognostic (3.45e-1)" "unprognostic (7.58e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-2)" "unprognostic (3.38e-1)" "unprognostic (3.30e-2)" "prognostic favourable (2.22e-14)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (2.23e-2)" "unprognostic (5.88e-3)" 18.9 20.8 12.3 14.5 18.5 8.7 11.0 14.3 23.7 10.1 19.4 15.9 13.5 29.0 16.2 11.1 19.5 11.1 11.8 73.9 11.3 12.8 28.8 14.8 13.0 11.1 14.2 11.7 9.8 13.0 25.5 11.0 14.5 22.2 12.3 13.3 22.3 23.7 15.9 99.3 15.6 35.5 16.4 10.1 12.1 14.9 11.3 11.0 11.3 17.8 39.8 15.8 13.0 10.8 7.2 13.4 7.5 20.4 11.2 25.7 11.6 10.8 22.8 13.7 20.8 21.2 23.3 13.4 17.0 16.6 19.4 16.9 20.8 22.5 47.8 20.2 24.7 33.8 27.0 25.4 18.9 27.9 7.1 14.5 46.2 10.2 10.8 17.9 16.3 21.6 19.3 27.4 19.7 26.2 16.7 14.3 20.4 15.3 17.7 10.3 12.6 25.8 17.0 9.6 53.7 22.2 32.4 23.4 11.2 24.6 34.1 10.6 20.2 18.0 20.6 14.0 12.6 24.2 19.6 13.0 24.9 26.4 25.3 20.3 25.3 4.8 12.1 7.3 11.7 17.7 12.8 7.2 13.5 11.7 13.4 5.9 5.8 7.0 7.5 11.2 20.4 6.6 25.7 11.6 12.3 18.5 14.3 23.7 11.3 12.8 14.2 11.7 22.2 11.0 OGG1 "HMMH, HOGG1, MUTM, OGH1" ENSG00000114026 "8-oxoguanine DNA glycosylase" O15527 3 9749944-9788219 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027514, CAB047301" Approved Enhanced Nucleoplasm Nucleoplasm "CAB047301: , HPA027514: AB_10602189" "unprognostic (6.95e-2)" "unprognostic (7.82e-3)" "unprognostic (7.19e-2)" "unprognostic (1.24e-3)" "unprognostic (9.69e-2)" "unprognostic (1.97e-2)" "prognostic unfavourable (5.77e-5)" "unprognostic (7.83e-2)" "unprognostic (2.45e-2)" "unprognostic (3.43e-3)" "unprognostic (9.66e-3)" "unprognostic (4.23e-2)" "prognostic favourable (2.65e-4)" "unprognostic (2.06e-2)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.59e-1)" 10.4 12.9 15.4 28.5 16.2 12.7 11.5 22.0 17.7 16.7 18.8 16.2 10.5 22.0 16.2 13.1 10.0 14.7 12.1 10.7 14.7 10.8 30.1 17.8 9.9 28.5 12.3 14.1 22.5 12.0 5.8 10.2 10.3 15.3 14.4 10.2 14.6 14.3 13.2 7.4 11.5 28.2 12.1 13.6 14.1 10.8 7.3 15.6 19.8 12.2 6.3 25.5 12.2 13.3 12.2 11.9 15.4 8.5 19.4 15.4 8.3 5.7 10.7 10.9 6.8 10.7 12.3 20.1 7.5 7.7 11.5 13.8 10.3 5.7 35.0 5.0 9.5 5.6 6.4 8.2 4.9 12.4 9.2 17.4 17.3 14.7 11.3 6.7 11.2 12.2 10.5 19.9 8.5 14.2 5.5 5.7 10.9 10.7 5.4 6.7 5.7 15.4 4.0 7.3 11.4 6.4 2.9 4.9 8.6 9.6 7.8 5.8 12.4 11.5 9.2 11.7 12.4 9.1 12.2 5.7 8.1 18.0 9.4 19.5 7.2 11.3 8.5 15.4 15.1 6.6 14.6 10.4 13.0 12.3 7.6 12.2 10.2 9.6 2.1 19.4 5.3 11.9 15.4 8.3 15.4 16.2 22.0 17.7 14.7 10.8 12.3 14.1 15.3 15.6 OGT "FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1" ENSG00000147162 "O-linked N-acetylglucosamine (GlcNAc) transferase" O15294 X 71533083-71575897 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Glycosyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030751, HPA030752, HPA030753, HPA030754, CAB034099" Approved Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "CAB034099: AB_2157067, HPA030751: AB_10600217, HPA030752: AB_10601445, HPA030753: AB_2673594, HPA030754: " "unprognostic (1.37e-1)" "unprognostic (2.20e-1)" "unprognostic (2.32e-2)" "prognostic unfavourable (8.33e-4)" "unprognostic (3.40e-2)" "prognostic favourable (1.97e-4)" "unprognostic (9.56e-3)" "unprognostic (1.96e-3)" "unprognostic (5.58e-2)" "unprognostic (2.29e-1)" "unprognostic (1.06e-1)" "unprognostic (9.74e-3)" "prognostic unfavourable (2.36e-6)" "unprognostic (2.99e-3)" "unprognostic (2.28e-1)" "unprognostic (8.03e-3)" "prognostic favourable (6.85e-7)" 26.1 24.0 33.3 39.7 36.6 38.7 33.7 75.7 43.8 25.0 23.0 22.0 31.1 22.5 36.7 48.3 24.3 33.4 21.2 25.1 29.3 15.4 27.4 20.3 31.0 47.9 30.2 25.6 42.8 46.1 26.5 34.5 19.5 26.6 34.2 30.3 29.9 35.9 30.9 35.0 45.4 38.4 31.1 32.3 56.7 28.2 11.8 36.6 35.7 34.1 27.6 41.4 24.9 31.0 9.7 7.6 3.2 7.2 12.5 9.9 6.0 14.3 13.5 17.5 15.3 18.9 17.4 11.8 11.0 19.9 12.0 18.5 14.2 16.5 17.1 7.8 13.5 17.9 19.1 10.8 14.8 14.6 19.6 10.8 32.1 10.1 14.3 22.2 17.9 16.6 22.0 13.1 24.8 11.1 10.9 59.5 11.4 12.2 17.1 26.7 11.6 18.4 17.0 19.6 21.9 18.5 16.7 9.0 7.9 17.1 11.4 10.6 8.4 15.1 12.9 13.0 10.6 13.5 6.4 16.3 11.7 20.6 9.1 23.4 7.9 3.2 5.3 2.3 9.9 7.2 9.0 9.7 8.3 8.0 7.5 8.5 9.7 9.5 2.4 12.5 6.5 7.6 7.6 6.0 33.3 36.6 75.7 43.8 29.3 15.4 30.2 25.6 26.6 36.6 OLAH "FLJ11106, SAST, THEDC1" ENSG00000152463 "Oleoyl-ACP hydrolase" Q9NV23 10 15032227-15073852 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "placenta: 61.3;testis: 24.0" "Cell line enhanced" "Detected in some" "HSkMC: 5.8;hTCEpi: 7.3;LHCN-M2: 5.6;SK-BR-3: 8.8;U-266/70: 4.9" "Group enriched" "Detected in some" 7 "testis cancer: 3.6;thyroid cancer: 0.8" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "neutrophil: 6.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.6" "HPA037947, HPA037948" Enhanced "HPA037947: AB_10795028, HPA037948: AB_10805352" "unprognostic (2.01e-1)" "unprognostic (6.12e-2)" "unprognostic (8.20e-3)" "unprognostic (4.04e-3)" "unprognostic (1.92e-1)" "unprognostic (8.09e-2)" "unprognostic (7.12e-2)" "unprognostic (5.12e-2)" "unprognostic (4.55e-1)" "unprognostic (3.74e-2)" "unprognostic (4.70e-1)" "unprognostic (1.69e-1)" "unprognostic (5.22e-10)" "unprognostic (4.55e-2)" "unprognostic (2.09e-1)" "unprognostic (5.11e-2)" "unprognostic (9.78e-2)" 1.0 1.1 0.2 0.2 0.7 1.2 5.2 0.3 0.7 0.8 0.5 0.3 0.1 0.0 0.2 0.4 2.7 1.4 1.1 0.8 0.2 0.2 0.8 0.4 1.9 4.3 0.9 0.1 0.2 0.1 0.1 1.5 61.3 0.4 0.1 0.0 0.3 3.0 0.1 0.5 0.4 0.3 0.1 0.5 8.0 0.2 24.0 0.3 0.2 1.2 0.1 0.3 0.3 1.1 0.5 1.1 6.6 0.4 1.0 0.6 0.1 0.2 0.6 0.6 0.5 0.3 1.1 2.2 0.4 0.4 0.2 0.1 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.7 0.4 0.2 0.3 0.4 0.0 0.9 0.0 0.6 5.8 7.3 0.9 0.1 0.7 0.5 0.3 5.6 0.0 0.5 0.7 0.7 0.4 0.7 1.3 1.7 0.0 0.0 0.0 0.4 0.3 8.8 0.1 0.2 0.5 1.0 0.1 2.9 1.3 0.1 4.9 1.6 0.4 2.7 0.5 0.0 1.4 0.4 0.4 0.4 0.2 0.3 0.2 0.6 0.2 0.2 0.5 0.3 0.3 6.6 1.0 0.2 1.1 0.4 0.1 0.2 0.7 0.3 0.3 0.2 0.2 0.9 0.1 0.4 0.3 OMA1 "FLJ33782, MPRP-1, YKR087C, ZMPOMA1" ENSG00000162600 "OMA1 zinc metallopeptidase" Q96E52 1 58415384-58546802 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055120 Approved Approved Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA055120: " "prognostic favourable (1.63e-4)" "unprognostic (2.67e-2)" "prognostic favourable (7.70e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-1)" "unprognostic (9.57e-2)" "unprognostic (3.94e-3)" "prognostic favourable (8.52e-4)" "unprognostic (8.22e-3)" "unprognostic (6.91e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (9.54e-3)" "unprognostic (2.52e-2)" "unprognostic (3.93e-2)" "unprognostic (1.74e-2)" "unprognostic (5.24e-3)" 10.2 22.4 13.8 21.5 18.1 9.2 15.8 10.6 14.6 14.5 16.4 14.1 20.1 12.1 15.4 15.1 17.1 15.9 12.1 15.8 12.6 10.0 23.0 23.8 19.1 17.9 16.7 9.6 15.0 18.2 15.7 20.9 8.9 13.0 17.8 16.1 11.3 20.6 22.7 20.9 10.2 16.1 24.2 18.2 17.2 13.9 6.9 19.4 18.4 18.3 14.5 16.4 17.0 20.6 22.5 9.5 18.6 19.5 18.6 22.8 10.2 13.5 5.7 3.8 3.5 19.2 18.0 10.9 5.6 6.1 4.9 6.2 1.6 8.2 30.7 11.9 5.8 13.9 13.4 13.7 5.9 23.5 7.5 9.6 4.4 6.6 9.6 23.3 6.7 17.0 15.3 4.8 10.0 4.3 18.0 9.2 13.4 8.3 7.9 8.3 5.6 12.4 9.9 12.5 12.8 10.7 9.1 4.0 1.9 11.4 18.9 15.8 8.5 9.0 2.5 2.5 5.1 12.6 5.8 7.5 9.8 20.2 7.8 18.3 6.2 10.8 9.2 18.6 12.8 14.5 16.5 22.5 15.7 15.0 9.5 21.4 22.8 20.8 10.6 18.6 19.5 5.0 13.9 10.2 13.8 18.1 10.6 14.6 12.6 10.0 16.7 9.6 13.0 19.4 OPA1 "FLJ12460, KIAA0567, MGM1, NPG, NTG" ENSG00000198836 "OPA1, mitochondrial dynamin like GTPase" O60313 3 193593144-193697823 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Sensory transduction, Vision" Hydrolase "Cardiomyopathy, Deafness, Disease mutation, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036926, HPA036927" Supported Supported Nucleoplasm,Mitochondria 13000 "Nucleoplasm, Mitochondria" "HPA036926: AB_10671247, HPA036927: " "unprognostic (2.10e-2)" "unprognostic (9.23e-3)" "unprognostic (7.98e-2)" "prognostic unfavourable (8.61e-4)" "unprognostic (1.62e-2)" "unprognostic (4.59e-2)" "unprognostic (2.24e-1)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (8.44e-5)" "unprognostic (3.48e-2)" "prognostic favourable (1.84e-4)" "unprognostic (2.92e-1)" "unprognostic (4.75e-1)" "unprognostic (4.50e-3)" "unprognostic (3.21e-1)" 17.0 19.7 18.2 13.5 31.7 25.9 15.9 20.2 30.9 13.9 21.8 11.1 12.6 20.0 15.2 11.8 18.8 11.8 12.8 43.9 23.0 19.4 21.8 24.1 10.7 15.3 19.0 22.4 13.2 13.4 20.9 15.6 13.8 28.0 15.5 20.5 9.1 15.7 20.8 38.4 14.6 17.3 16.5 17.0 13.1 16.7 7.6 10.8 18.0 16.8 18.4 14.2 16.5 13.6 8.3 8.8 8.2 17.6 5.0 7.5 5.9 25.9 8.3 8.5 9.3 7.5 11.9 9.0 12.6 11.6 13.9 13.6 20.3 8.8 17.3 27.3 11.8 16.9 14.8 14.3 24.6 20.8 12.0 29.9 7.4 10.1 11.7 24.5 13.8 13.2 12.8 13.4 19.0 11.7 12.6 17.0 13.8 20.5 9.5 13.6 11.9 27.9 12.5 18.6 18.5 10.4 16.2 18.5 11.2 18.9 21.1 13.4 27.7 19.4 11.7 12.9 9.8 13.8 26.5 15.3 17.8 33.8 14.2 19.7 12.9 8.2 8.1 7.7 7.2 9.3 6.6 8.3 6.8 6.8 8.8 6.3 6.9 7.3 3.2 5.0 17.6 4.6 7.5 5.9 18.2 31.7 20.2 30.9 23.0 19.4 19.0 22.4 28.0 10.8 OPLAH "5-Opase, OPLA" ENSG00000178814 "5-oxoprolinase, ATP-hydrolysing" O14841 8 144051266-144063965 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.3" "Cell line enhanced" "Detected in many" "AN3-CA: 22.2;BEWO: 13.9;Hep G2: 11.9;PC-3: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.0;intermediate monocyte: 1.0;neutrophil: 3.8" "Group enriched" "Detected in many" 9 "granulocytes: 3.8;monocytes: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026562, HPA028260, HPA052429" Uncertain Approved "Nucleoli fibrillar center" "Nucleoli fibrillar center" "HPA026562: AB_1854804, HPA028260: AB_10601383, HPA052429: " "unprognostic (7.89e-2)" "unprognostic (3.08e-2)" "unprognostic (1.69e-1)" "unprognostic (9.09e-2)" "unprognostic (2.21e-2)" "unprognostic (3.87e-3)" "unprognostic (2.04e-2)" "unprognostic (9.37e-2)" "unprognostic (2.90e-1)" "unprognostic (1.26e-1)" "unprognostic (6.82e-2)" "unprognostic (3.62e-1)" "prognostic favourable (1.53e-6)" "unprognostic (4.03e-3)" "unprognostic (4.33e-1)" "unprognostic (3.54e-2)" "unprognostic (8.24e-2)" 5.6 5.6 3.3 1.7 3.9 2.3 3.1 4.9 5.3 1.9 7.0 7.0 4.5 11.8 1.6 1.9 5.9 1.3 5.2 16.2 2.5 1.7 10.8 17.2 2.9 2.0 4.5 4.2 2.0 6.0 5.8 1.2 1.3 5.5 3.5 2.0 4.8 9.4 5.6 25.6 5.5 10.4 1.2 4.4 3.7 7.2 49.3 4.9 0.3 1.9 5.4 1.8 2.1 3.3 0.0 0.3 3.8 3.0 0.0 0.1 0.8 2.7 2.7 0.3 22.2 1.0 2.1 13.9 1.3 0.9 0.8 0.4 5.1 5.0 0.0 4.5 2.4 3.5 0.7 2.0 0.0 0.7 0.0 0.9 4.0 11.9 7.1 0.1 0.0 2.9 9.2 0.9 0.0 0.1 3.2 0.0 0.0 3.0 0.2 2.1 1.9 17.2 0.2 0.0 3.4 2.4 3.2 0.8 0.1 0.0 0.9 0.0 5.7 2.9 0.1 0.0 3.7 0.0 0.9 0.7 0.9 0.6 0.3 0.7 0.0 0.0 3.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 3.8 0.0 0.4 0.0 0.0 0.8 3.3 3.9 4.9 5.3 2.5 1.7 4.5 4.2 5.5 4.9 OSGEP "GCPL1, KAE1, OSGEP1, PRSMG1, TCS3" ENSG00000092094 "O-sialoglycoprotein endopeptidase" Q9NPF4 14 20446411-20455105 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039751 Uncertain Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA039751: AB_10794754" "prognostic favourable (1.48e-4)" "unprognostic (4.15e-3)" "unprognostic (1.29e-1)" "unprognostic (4.33e-3)" "unprognostic (1.54e-2)" "unprognostic (3.95e-2)" "unprognostic (5.54e-3)" "unprognostic (2.80e-3)" "unprognostic (2.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.35e-3)" "unprognostic (1.22e-1)" "prognostic unfavourable (4.64e-6)" "unprognostic (4.83e-2)" "unprognostic (1.86e-2)" "unprognostic (2.53e-2)" "unprognostic (9.91e-2)" 11.2 14.2 13.2 13.1 14.5 10.7 14.4 21.3 18.3 14.3 15.6 18.6 11.6 8.8 16.0 19.2 12.9 13.1 13.6 15.8 13.4 10.2 12.3 22.2 12.4 16.9 13.4 12.5 12.4 12.4 10.6 20.8 13.6 15.5 10.8 14.0 14.5 12.4 18.6 19.6 9.9 12.4 16.8 12.3 18.8 13.6 5.7 15.2 16.2 15.7 9.6 18.7 16.6 11.0 24.5 28.8 23.4 19.1 13.0 14.2 15.7 6.3 10.3 3.4 10.0 5.9 4.1 10.5 5.0 6.6 12.8 12.4 14.2 7.5 13.3 6.5 6.3 5.6 10.3 10.1 8.0 10.5 13.2 8.4 8.7 18.2 4.4 14.4 12.0 3.1 3.1 15.3 8.1 8.4 8.1 7.6 10.0 11.9 14.1 6.3 5.1 20.4 22.5 6.4 7.5 7.2 7.3 13.3 2.6 8.9 9.4 6.8 6.3 13.7 3.9 5.4 13.2 6.8 6.0 2.3 12.5 18.2 3.3 22.5 6.5 5.1 19.1 23.4 13.7 17.6 11.9 20.5 14.2 12.0 28.8 24.5 11.3 12.9 8.7 13.0 13.6 12.4 12.9 15.7 13.2 14.5 21.3 18.3 13.4 10.2 13.4 12.5 15.5 15.2 OSGEPL1 "OSGEPL, Qri7" ENSG00000128694 "O-sialoglycoprotein endopeptidase like 1" Q9H4B0 2 189746660-189763227 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030693 Uncertain Supported Mitochondria Mitochondria "HPA030693: AB_10601978" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (8.19e-2)" "unprognostic (6.70e-2)" "unprognostic (6.07e-2)" "unprognostic (6.38e-2)" "prognostic unfavourable (3.71e-4)" "unprognostic (4.18e-3)" "unprognostic (1.06e-3)" "prognostic favourable (3.19e-4)" "unprognostic (2.33e-1)" "unprognostic (1.80e-2)" "unprognostic (3.34e-2)" "unprognostic (2.68e-1)" "unprognostic (1.51e-2)" "unprognostic (6.39e-2)" "unprognostic (1.55e-3)" 6.6 17.0 8.6 6.5 12.1 2.6 11.1 12.9 10.9 7.3 5.6 14.8 2.9 5.0 11.8 9.1 7.0 8.1 4.8 13.0 8.4 7.3 13.0 11.6 5.8 11.2 18.9 9.3 13.8 6.1 7.5 9.8 6.1 11.6 6.9 6.1 9.0 9.7 6.1 16.6 9.2 6.5 8.1 13.4 9.6 5.8 9.4 15.4 10.6 8.2 7.3 9.2 8.0 5.8 9.3 6.0 2.1 2.6 6.6 11.5 3.0 5.7 3.2 14.1 10.8 11.2 6.2 8.4 8.9 6.3 12.7 13.7 3.7 6.0 3.8 10.0 3.7 8.4 12.5 10.6 14.5 9.8 9.6 12.4 7.8 4.8 5.9 7.0 6.5 6.8 9.0 9.6 4.7 9.4 4.5 6.1 8.3 3.2 5.5 8.0 6.8 14.6 6.0 11.3 6.5 8.2 3.2 8.6 9.5 6.0 10.9 19.4 8.5 7.7 3.9 8.3 7.3 12.1 5.5 6.2 5.2 6.2 11.0 9.0 9.0 0.2 2.6 2.1 7.3 2.4 10.5 7.4 7.7 8.4 3.5 9.3 11.5 10.2 0.4 6.6 2.1 6.0 5.9 3.0 8.6 12.1 12.9 10.9 8.4 7.3 18.9 9.3 11.6 15.4 OTC ENSG00000036473 "Ornithine carbamoyltransferase" P00480 X 38352545-38421450 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "intestine: 59.1;liver: 90.3" "Cell line enhanced" "Detected in some" "NB-4: 1.8;RPMI-8226: 1.0;SH-SY5Y: 1.1;SiHa: 1.8" "Cancer enriched" "Detected in some" 20 "liver cancer: 59.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000243, HPA000570" Enhanced Supported Mitochondria 1800000 Mitochondria "HPA000243: AB_1079535, HPA000570: AB_1079534" "unprognostic (6.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.89e-3)" "unprognostic (4.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.70e-3)" "unprognostic (5.61e-2)" 0.4 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.1 0.8 16.5 0.0 0.2 26.9 1.1 0.2 0.2 0.3 5.3 0.2 0.1 0.2 0.1 90.3 0.7 2.3 0.2 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.1 0.1 59.1 0.8 0.3 0.1 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.6 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.2 0.0 0.0 0.0 OTUB1 "FLJ20113, FLJ40710" ENSG00000167770 "OTU deubiquitinase, ubiquitin aldehyde binding 1" Q96FW1 11 63985853-64001811 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, DNA damage, DNA repair, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039176, CAB072836" Approved Supported Approved Nucleoplasm,Cytosol 630000 "Nucleoplasm, Cytosol" "CAB072836: , HPA039176: AB_10674980" "unprognostic (2.50e-1)" "unprognostic (5.70e-3)" "unprognostic (3.93e-2)" "unprognostic (1.63e-1)" "unprognostic (2.78e-1)" "prognostic unfavourable (3.05e-4)" "unprognostic (1.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.45e-1)" "unprognostic (1.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (6.76e-2)" "unprognostic (1.42e-1)" "unprognostic (4.84e-2)" "unprognostic (1.82e-1)" 19.8 24.7 41.9 24.1 61.6 32.6 20.8 41.8 101.9 24.3 25.0 31.9 22.3 24.7 21.9 23.6 37.8 34.5 21.6 31.6 46.9 37.8 27.2 27.6 23.0 31.9 33.1 45.4 23.4 23.0 26.0 21.6 30.7 60.4 23.8 24.1 24.2 30.4 27.7 26.7 36.9 26.0 23.1 26.7 25.7 23.9 22.1 21.2 27.8 29.9 24.5 32.8 27.1 22.9 46.0 60.8 56.1 71.3 44.8 64.5 78.2 30.5 55.2 30.5 26.9 20.6 22.8 23.4 18.4 27.4 41.0 30.3 37.0 29.3 16.3 35.0 29.5 38.2 39.3 45.8 25.5 18.8 30.5 27.1 33.1 46.8 28.9 26.9 29.8 24.2 29.8 31.3 20.0 38.6 18.9 18.5 27.5 62.8 29.3 35.6 35.7 26.3 24.1 11.9 27.8 42.6 44.7 23.1 33.3 20.8 32.0 33.6 49.6 23.8 27.9 21.9 21.3 29.3 24.1 21.8 13.7 23.3 28.3 17.5 20.9 55.1 56.3 54.3 53.1 71.3 41.4 46.0 49.1 48.6 60.8 41.9 38.4 42.6 56.1 44.8 60.9 42.1 64.5 78.2 41.9 61.6 41.8 101.9 46.9 37.8 33.1 45.4 60.4 21.2 OTUB2 "C14orf137, FLJ21916, MGC3102" ENSG00000089723 "OTU deubiquitinase, ubiquitin aldehyde binding 2" Q96DC9 14 94026329-94048930 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.5" "Cell line enhanced" "Detected in many" "Karpas-707: 18.2;RPTEC TERT1: 11.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 2.5;myeloid DC: 3.3;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 5 "dendritic cells: 3.3;monocytes: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002329 Enhanced "HPA002329: AB_1079537" "unprognostic (6.80e-3)" "unprognostic (1.39e-3)" "unprognostic (3.68e-3)" "unprognostic (4.82e-3)" "unprognostic (1.66e-1)" "unprognostic (2.20e-1)" "unprognostic (2.30e-3)" "unprognostic (1.18e-2)" "unprognostic (2.55e-1)" "unprognostic (3.09e-3)" "unprognostic (2.80e-2)" "unprognostic (1.16e-2)" "unprognostic (6.25e-3)" "unprognostic (1.15e-1)" "unprognostic (2.06e-2)" "unprognostic (1.02e-4)" "unprognostic (3.16e-1)" 2.3 1.3 2.6 0.5 3.3 0.4 1.7 1.0 5.3 2.9 1.0 0.8 1.9 0.7 1.7 1.4 5.2 1.2 0.8 0.4 3.3 1.1 1.7 1.5 0.7 0.6 0.8 1.3 1.6 1.7 4.6 1.0 6.2 1.4 1.2 1.6 0.8 1.9 0.5 0.3 9.5 0.7 0.6 1.0 0.6 1.0 34.5 0.5 0.0 0.6 1.0 2.6 1.7 2.0 0.2 3.3 0.2 2.5 0.0 0.5 0.9 1.3 3.6 2.4 2.3 1.0 0.8 2.8 0.5 0.3 1.5 2.1 0.8 5.9 0.3 2.3 0.6 0.3 3.2 1.7 1.2 0.8 1.4 0.1 0.4 3.7 1.3 0.0 0.6 0.6 2.2 0.5 0.9 1.6 0.1 18.2 0.7 1.2 0.1 0.4 0.7 3.1 0.1 0.2 1.0 11.4 1.7 1.8 1.3 0.7 0.8 1.9 6.4 0.8 1.6 1.0 2.9 0.7 1.0 3.0 2.1 0.0 1.8 0.9 1.4 0.0 2.1 0.0 0.3 2.5 0.0 0.2 0.4 0.5 3.3 0.0 0.2 0.0 0.2 0.0 1.9 0.1 0.2 0.9 2.6 3.3 1.0 5.3 3.3 1.1 0.8 1.3 1.4 0.5 OTUD1 "DUBA7, OTDC1" ENSG00000165312 "OTU deubiquitinase 1" Q5VV17 10 23439458-23442390 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.8;tongue: 61.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 24.7;HaCaT: 23.3;SiHa: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038503, HPA038504" Uncertain Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA038503: , HPA038504: AB_10672712" "unprognostic (1.84e-1)" "unprognostic (2.80e-2)" "unprognostic (1.96e-1)" "prognostic unfavourable (4.59e-4)" "unprognostic (1.56e-1)" "unprognostic (1.29e-2)" "unprognostic (3.18e-3)" "unprognostic (2.41e-1)" "unprognostic (7.77e-2)" "unprognostic (4.10e-2)" "unprognostic (1.80e-2)" "unprognostic (1.32e-1)" "prognostic favourable (6.61e-7)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-2)" 11.6 9.2 5.9 8.5 6.9 39.3 14.7 9.7 9.5 13.8 8.8 9.3 6.9 4.9 9.8 10.0 8.2 9.0 9.9 25.9 6.0 5.9 14.7 7.3 26.6 11.0 6.2 6.7 10.9 6.5 12.8 7.8 11.5 5.4 8.0 5.8 9.8 6.4 6.2 60.8 17.5 7.9 7.3 6.5 13.1 16.9 9.9 5.8 8.1 14.9 61.1 12.3 12.7 10.5 3.5 1.0 5.1 4.0 0.2 3.5 0.5 2.9 1.4 1.6 0.7 6.3 3.2 2.0 1.2 2.7 2.9 2.6 0.6 24.7 1.4 2.6 1.5 23.3 1.7 2.9 1.9 10.5 4.5 0.0 3.6 0.9 5.4 0.2 2.0 3.2 12.9 0.8 4.1 0.9 0.3 9.9 1.6 1.4 0.9 0.9 1.2 0.8 1.5 7.1 1.3 3.8 2.6 0.7 1.7 15.1 2.7 6.8 1.1 2.1 1.7 1.6 2.4 4.5 0.5 4.8 9.0 0.7 2.5 0.9 0.6 5.1 1.6 2.6 0.8 1.7 1.0 1.9 1.5 0.8 1.0 3.5 1.2 1.7 3.6 0.2 4.0 0.6 3.5 0.5 5.9 6.9 9.7 9.5 6.0 5.9 6.2 6.7 5.4 5.8 OTUD3 "DUBA4, KIAA0459" ENSG00000169914 "OTU deubiquitinase 3" Q5T2D3 1 19882513-19912945 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028543, HPA028544" Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" Cytosol "Nucleoplasm, Intermediate filaments" "HPA028543: AB_10599302, HPA028544: AB_10602277" "unprognostic (6.45e-3)" "unprognostic (9.26e-2)" "unprognostic (3.77e-1)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" "unprognostic (3.16e-3)" "unprognostic (1.70e-3)" "unprognostic (3.15e-3)" "unprognostic (4.99e-2)" "unprognostic (1.09e-1)" "unprognostic (8.81e-2)" "unprognostic (4.68e-2)" "unprognostic (1.08e-1)" "unprognostic (9.83e-2)" "unprognostic (1.94e-1)" "unprognostic (7.28e-2)" "unprognostic (2.21e-2)" 6.5 11.0 15.0 6.9 19.2 11.4 10.0 19.3 23.2 10.6 8.9 6.6 6.4 10.2 14.2 13.0 6.1 8.2 7.2 5.2 12.6 7.3 7.1 4.8 8.5 7.0 9.9 12.5 11.2 7.2 9.3 20.2 5.4 9.0 9.8 8.3 6.9 6.2 9.2 9.2 13.0 9.6 11.9 8.1 7.7 7.3 28.4 9.7 6.0 6.9 2.9 6.3 7.0 7.6 1.7 0.6 0.8 0.4 0.6 2.2 0.3 5.0 1.9 8.6 10.3 3.7 3.3 8.5 5.4 3.1 2.8 2.7 9.0 4.8 8.0 4.4 11.9 5.0 8.0 3.1 5.5 5.2 10.7 7.7 10.2 6.2 2.0 5.6 7.1 2.7 3.1 4.4 5.7 3.7 5.4 3.4 4.8 2.7 4.3 5.6 4.1 5.1 10.0 22.0 3.0 4.7 5.5 7.6 5.4 3.9 3.1 4.2 4.7 4.2 4.4 6.7 8.6 7.4 4.6 4.0 3.4 5.0 4.7 7.6 3.1 0.8 0.4 0.1 1.5 0.3 1.4 1.7 1.7 1.4 0.3 1.3 2.2 1.8 0.7 0.6 0.1 0.6 0.9 0.3 15.0 19.2 19.3 23.2 12.6 7.3 9.9 12.5 9.0 9.7 OTUD4 "DUBA6, HSHIN1, KIAA1046" ENSG00000164164 "OTU deubiquitinase 4" Q01804 4 145110838-145180161 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036623 Uncertain Supported Cytosol Cytosol "HPA036623: AB_10696780" "unprognostic (1.67e-1)" "unprognostic (4.18e-2)" "unprognostic (3.41e-2)" "unprognostic (1.95e-1)" "unprognostic (2.80e-1)" "unprognostic (4.06e-2)" "unprognostic (3.42e-2)" "unprognostic (2.66e-2)" "unprognostic (1.21e-1)" "unprognostic (1.74e-2)" "unprognostic (5.21e-3)" "unprognostic (2.03e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (2.62e-1)" 14.3 11.8 16.6 11.6 16.7 24.7 12.0 22.7 15.9 14.0 15.3 16.0 10.1 10.0 13.9 13.3 14.8 14.9 11.2 15.6 12.0 9.2 11.1 17.7 15.5 13.1 14.1 8.4 14.3 13.4 22.4 12.2 17.9 12.7 10.6 11.2 10.6 12.7 11.0 36.2 13.6 16.2 12.4 10.1 13.5 10.8 26.8 18.8 13.1 13.4 13.6 12.3 11.5 12.8 3.3 2.8 2.8 2.8 1.6 3.5 1.0 14.9 8.5 10.2 9.4 12.1 14.8 13.7 13.1 14.8 16.9 13.5 9.2 18.5 27.5 6.0 18.3 9.1 17.6 18.3 22.2 11.7 8.4 13.2 10.4 8.4 14.2 27.6 10.0 11.5 18.7 20.6 27.2 14.9 21.7 20.6 16.6 8.9 17.1 12.1 11.4 9.8 14.1 11.3 6.4 16.3 10.9 9.9 8.2 12.1 18.3 13.1 6.0 11.4 18.0 19.1 12.2 9.8 17.3 15.2 15.0 18.2 13.2 19.6 18.4 0.0 1.7 2.8 3.5 2.1 2.6 3.3 2.7 2.8 1.6 2.4 2.7 2.4 0.5 1.6 2.8 2.8 2.0 1.0 16.6 16.7 22.7 15.9 12.0 9.2 14.1 8.4 12.7 18.8 OTUD5 "DKFZp761A052, DUBA" ENSG00000068308 "OTU deubiquitinase 5" Q96G74 X 48922028-48958386 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "U-266/70: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017375 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoplasm, Nucleoli fibrillar center" "HPA017375: AB_1854844" "unprognostic (9.73e-2)" "prognostic favourable (9.57e-4)" "unprognostic (2.67e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (6.65e-2)" "unprognostic (2.33e-3)" "prognostic favourable (1.48e-4)" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "prognostic favourable (8.20e-4)" "unprognostic (1.32e-1)" "unprognostic (3.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (4.88e-2)" "unprognostic (5.05e-3)" 23.5 27.5 32.4 26.8 40.9 38.4 21.9 35.0 52.4 21.3 22.9 28.2 23.4 30.5 25.5 26.8 20.5 25.1 20.9 16.6 29.8 31.3 22.6 24.5 25.2 30.8 25.4 29.8 30.0 25.4 29.6 26.8 23.1 29.4 24.0 17.8 20.4 26.9 27.4 24.4 24.5 29.1 27.1 21.4 34.5 22.3 12.7 24.0 34.8 24.5 14.4 27.2 22.1 22.7 7.8 6.3 8.6 5.1 18.6 7.5 3.5 6.1 9.3 4.3 10.7 7.4 6.6 5.0 5.4 6.3 6.8 7.4 4.6 6.8 6.9 3.5 6.8 7.5 6.5 5.4 6.4 8.0 7.9 5.2 9.4 5.3 6.2 4.9 5.8 7.3 5.1 7.1 4.8 5.4 6.5 10.9 4.8 6.1 7.7 10.7 7.8 7.3 6.1 6.4 8.9 4.8 5.5 4.2 7.4 7.1 4.6 7.1 6.1 4.5 7.6 4.4 5.6 11.7 4.4 182.8 45.6 6.6 6.9 6.9 3.0 5.2 3.4 7.0 7.0 5.1 5.8 7.8 5.5 6.0 4.8 6.0 5.2 7.5 8.6 18.6 4.7 6.3 7.0 3.5 32.4 40.9 35.0 52.4 29.8 31.3 25.4 29.8 29.4 24.0 OTUD6A "DUBA2, FLJ25831, HSHIN6" ENSG00000189401 "OTU deubiquitinase 6A" Q7L8S5 X 70062491-70064179 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "blood: 3.8;testis: 13.6" "Cell line enhanced" "Detected in some" "MCF7: 2.0;U-2 OS: 1.9" "Cancer enriched" "Detected in single" 57 "testis cancer: 2.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA053304 Enhanced "HPA053304: AB_2682107" "unprognostic (1.58e-1)" 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 13.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.4 3.8 0.4 0.7 0.6 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.6 0.4 1.0 0.5 0.0 0.7 0.4 0.2 0.2 0.0 0.0 0.5 0.8 0.8 0.0 0.3 0.7 0.3 0.4 0.2 0.2 0.0 0.2 0.6 0.0 2.0 0.3 0.9 0.6 0.2 0.0 0.0 0.0 0.8 0.7 0.6 0.3 0.5 0.2 0.0 0.1 0.1 0.0 0.2 1.9 0.3 0.5 1.6 0.3 1.5 0.1 0.2 0.2 3.8 0.4 0.3 0.4 0.2 0.4 0.3 0.3 0.2 0.0 0.9 0.3 0.6 2.6 0.7 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OTUD6B "CGI-77, DUBA5" ENSG00000155100 "OTU domain containing 6B" Q8N6M0 8 91070196-91087095 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024046, HPA024503, HPA024772" Approved Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA024046: AB_10600925, HPA024503: AB_1854845, HPA024772: AB_1854846" "prognostic unfavourable (7.50e-4)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (4.78e-3)" "unprognostic (4.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.52e-2)" "unprognostic (1.16e-3)" "unprognostic (2.17e-1)" "unprognostic (5.51e-2)" "unprognostic (1.27e-2)" "unprognostic (8.61e-3)" "unprognostic (1.87e-2)" "unprognostic (1.96e-1)" "unprognostic (4.53e-1)" "unprognostic (8.78e-2)" "unprognostic (5.71e-2)" 11.4 11.3 14.6 14.1 18.2 8.9 13.2 13.8 19.6 12.3 11.3 9.9 10.3 9.2 12.1 9.0 13.2 9.1 8.6 14.0 14.9 13.7 11.0 10.5 10.0 13.8 18.5 15.5 12.5 9.9 11.2 14.4 14.9 16.2 11.6 11.3 6.0 9.5 14.8 35.3 11.2 9.1 12.4 19.9 11.3 8.8 11.9 17.4 13.9 11.8 11.0 11.9 11.9 14.0 7.2 12.9 8.8 7.8 7.8 6.8 2.9 16.0 9.3 8.3 6.2 3.7 2.8 8.7 12.7 4.8 11.9 7.7 7.9 10.1 17.1 6.2 6.7 5.5 17.2 10.4 18.5 13.7 10.5 23.2 9.6 6.0 8.0 11.8 12.3 4.7 5.0 9.6 22.7 9.6 23.2 10.7 10.1 8.7 19.8 7.7 4.5 18.4 8.9 8.0 15.2 9.3 11.6 2.0 7.5 1.2 28.3 12.3 14.5 5.7 9.8 7.1 10.7 10.8 12.1 10.7 20.4 25.0 10.4 14.8 13.6 8.8 6.5 4.3 5.9 7.8 6.8 7.2 4.8 5.7 8.1 6.8 6.7 5.9 0.9 7.8 5.8 12.9 3.6 2.9 14.6 18.2 13.8 19.6 14.9 13.7 18.5 15.5 16.2 17.4 OTUD7A "C15orf16, CEZANNE2, OTUD7" ENSG00000169918 "OTU deubiquitinase 7A" Q8TE49 15 31475398-31870789 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044554 Uncertain Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA044554: AB_10794895" "unprognostic (3.61e-2)" "unprognostic (1.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.25e-3)" "unprognostic (1.29e-1)" "unprognostic (1.03e-4)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (3.24e-3)" "unprognostic (1.34e-1)" "unprognostic (1.79e-11)" "unprognostic (6.78e-2)" "unprognostic (2.76e-1)" "unprognostic (8.27e-2)" "unprognostic (1.79e-1)" 2.6 2.0 12.4 1.7 13.9 5.9 1.5 13.2 17.0 1.8 3.4 16.0 0.0 1.5 1.9 1.9 1.9 2.0 2.3 2.1 10.0 4.6 2.3 1.0 1.5 3.5 20.4 7.1 2.0 2.5 4.6 1.7 0.9 10.5 1.2 3.1 0.7 1.6 2.0 1.8 3.2 2.1 2.9 9.1 2.2 2.3 8.2 17.4 0.0 2.3 0.0 2.4 1.9 1.3 0.1 3.2 0.3 1.4 0.1 0.7 0.4 3.6 4.1 4.5 6.0 0.4 1.3 3.2 2.5 1.3 3.9 1.9 2.5 3.2 2.9 2.2 0.9 4.6 4.8 2.0 3.2 5.9 6.6 3.7 8.3 2.0 0.3 4.0 5.7 0.0 0.2 3.8 4.3 3.5 6.0 5.4 1.8 2.9 3.1 3.9 2.0 2.0 5.6 3.0 1.4 1.6 3.9 10.9 6.0 3.4 3.0 1.0 2.5 4.3 2.3 5.3 5.2 3.0 6.2 3.3 2.4 3.0 2.9 5.8 4.5 0.0 0.4 0.3 0.6 0.5 0.3 0.0 0.3 0.7 0.2 0.1 0.2 0.2 0.0 0.1 1.4 3.2 0.0 0.4 12.4 13.9 13.2 13.8 10.0 4.6 20.4 7.1 10.5 17.4 OTUD7B "CEZANNE, ZA20D1" ENSG00000264522 "OTU deubiquitinase 7B" Q6GQQ9 1 149937812-150010676 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 4.7" "Group enriched" "Detected in many" 4 "granulocytes: 4.7;NK-cells: 1.4;T-cells: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027045 Supported Approved Nucleoplasm,Microtubules "Nucleoplasm, Microtubules" "HPA027045: AB_1854847" "unprognostic (2.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.90e-1)" "prognostic favourable (7.47e-4)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.23e-3)" "unprognostic (1.46e-2)" "prognostic favourable (5.09e-5)" "unprognostic (4.90e-2)" "unprognostic (7.72e-2)" "unprognostic (8.94e-2)" "unprognostic (3.37e-2)" "unprognostic (1.67e-2)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (1.58e-2)" 8.8 6.2 5.8 2.6 12.3 0.3 6.2 8.5 8.9 8.6 6.3 20.6 4.0 4.6 8.5 4.1 6.1 7.6 4.3 5.3 6.0 4.5 8.6 5.6 0.9 12.7 5.1 9.2 4.5 12.5 4.3 5.3 11.6 5.3 5.6 7.4 5.4 6.3 13.2 4.3 5.1 8.9 8.5 2.3 5.2 9.6 12.5 0.0 8.3 2.3 2.1 6.3 7.1 0.6 0.6 4.7 0.3 1.4 2.3 0.2 11.4 9.2 6.5 10.8 8.6 8.0 6.1 8.1 11.9 9.7 6.7 6.8 9.3 0.1 5.3 14.6 9.2 9.1 8.9 10.3 11.0 4.7 4.4 12.8 4.5 9.2 5.0 4.8 8.8 6.9 16.5 14.5 7.9 12.0 12.5 7.0 11.7 0.8 1.4 8.2 9.0 1.2 8.9 2.9 3.8 15.7 4.2 7.9 14.2 10.5 12.8 8.7 2.6 9.5 10.1 9.4 6.8 9.4 13.4 12.9 1.3 9.0 1.5 16.5 4.7 0.3 1.3 2.3 0.2 1.7 0.6 1.0 1.4 0.1 0.6 0.9 1.0 1.2 1.4 0.3 0.6 0.6 0.2 OTULIN "FAM105B, FLJ34884" ENSG00000154124 "OTU deubiquitinase with linear linkage specificity" Q96BN8 5 14664664-14699711 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051074 Uncertain Approved "Plasma membrane,Mitochondria" Mitochondria "Plasma membrane" "HPA051074: " "unprognostic (4.81e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (1.19e-2)" "unprognostic (7.48e-2)" "unprognostic (1.91e-2)" "unprognostic (7.94e-3)" "unprognostic (1.43e-1)" "unprognostic (2.48e-2)" "unprognostic (9.55e-2)" "unprognostic (1.02e-1)" "unprognostic (7.13e-2)" "prognostic unfavourable (2.59e-7)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (5.02e-2)" 10.0 7.4 5.9 22.6 7.8 32.3 8.4 7.2 6.6 8.2 9.3 8.3 8.9 10.7 9.5 7.7 13.8 6.1 10.8 15.5 6.7 4.9 8.5 19.5 11.1 16.0 9.6 2.8 9.1 12.2 7.5 9.8 11.8 7.0 11.1 7.0 7.7 10.6 10.8 16.5 18.1 11.7 8.1 10.5 12.5 7.1 11.5 7.4 15.0 7.8 9.7 19.3 8.5 15.8 3.4 2.9 3.1 3.0 1.0 4.6 0.9 6.3 7.4 7.4 8.4 6.9 7.2 8.2 6.4 4.5 9.1 6.9 9.9 4.7 11.4 12.6 4.1 7.2 9.2 8.4 6.3 19.7 7.6 8.2 23.5 5.3 5.9 7.8 14.1 4.1 10.3 7.5 6.4 7.7 8.1 18.3 6.5 3.9 7.7 6.8 4.5 7.8 11.9 6.7 4.6 6.0 6.6 3.4 5.5 22.8 5.1 4.9 5.6 9.0 7.1 11.9 13.4 8.9 8.4 8.3 12.5 13.0 6.8 14.9 6.1 0.4 2.0 3.1 1.0 2.2 3.0 0.9 2.5 3.4 2.9 3.4 1.8 3.9 2.2 1.0 3.0 2.5 4.6 0.9 5.9 7.8 7.2 6.6 6.7 4.9 9.6 2.8 7.0 7.4 OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870519 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 108.8" "Cell line enhanced" "Detected in many" "HeLa: 56.1;SiHa: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" 1000000 Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favourable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" 21.9 8.0 17.3 7.5 30.3 5.8 9.5 26.6 36.8 6.7 9.2 8.3 10.7 4.4 8.6 8.7 13.1 6.9 7.5 108.8 19.3 15.2 25.3 1.2 4.2 9.5 13.1 25.7 7.2 3.0 20.9 8.4 2.8 21.2 12.5 10.4 6.6 8.5 14.7 13.4 10.7 6.5 17.0 8.9 5.2 14.6 6.2 5.3 22.8 13.0 10.7 11.8 8.0 7.5 8.0 4.6 3.3 1.6 7.5 15.6 5.1 7.8 0.3 6.5 7.7 20.1 10.8 0.0 14.1 8.9 11.7 7.1 1.2 5.4 20.4 3.5 10.7 4.6 17.8 12.7 13.8 17.4 2.0 14.3 56.1 2.6 8.8 27.7 4.8 10.1 3.4 11.5 19.4 10.7 2.9 26.3 13.4 1.0 23.1 1.3 1.4 5.6 18.4 18.2 15.4 9.5 0.6 6.5 6.7 72.9 0.0 8.6 0.1 6.0 6.4 9.3 12.2 15.9 11.3 4.3 3.6 0.8 14.1 20.4 7.1 1.0 1.0 3.3 9.1 1.1 10.9 8.0 9.2 9.8 4.6 6.1 10.8 8.9 0.3 7.5 1.6 1.8 15.6 5.1 17.3 30.3 26.6 36.8 19.3 15.2 13.1 25.7 21.2 5.3 OXCT2 "FKSG25, FLJ00030, SCOT-T" ENSG00000198754 "3-oxoacid CoA-transferase 2" Q9BYC2 1 39769523-39771348 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 31.8" "Cell line enhanced" "Detected in many" "Karpas-707: 9.8;THP-1: 10.5;U-266/70: 8.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "memory B-cell: 3.3;naive B-cell: 1.9;NK-cell: 1.4" "Group enriched" "Detected in many" 9 "B-cells: 3.3;NK-cells: 1.4" HPA075423 Enhanced "HPA075423: " "unprognostic (2.42e-3)" "unprognostic (2.11e-1)" "unprognostic (6.50e-2)" "unprognostic (7.16e-2)" "unprognostic (9.68e-2)" "unprognostic (1.13e-1)" "unprognostic (1.32e-1)" "unprognostic (1.93e-3)" "unprognostic (2.74e-1)" "unprognostic (3.16e-1)" "unprognostic (2.57e-3)" "unprognostic (4.18e-2)" "unprognostic (5.39e-5)" "unprognostic (3.24e-1)" "unprognostic (4.59e-1)" "unprognostic (1.70e-1)" "unprognostic (1.85e-1)" 0.0 0.6 0.2 0.2 0.2 0.1 0.0 0.8 0.5 0.3 0.3 0.4 0.5 0.7 0.4 0.2 0.5 3.9 0.4 0.1 0.0 0.1 0.0 0.3 0.3 1.5 0.4 0.2 0.3 0.0 0.8 0.2 0.0 1.2 0.0 1.4 0.5 0.4 0.4 0.3 0.2 31.8 1.6 0.0 0.1 0.0 3.3 0.0 0.0 0.2 1.4 0.0 0.1 0.5 0.3 0.0 1.2 0.4 1.4 0.0 1.4 0.0 1.4 0.7 4.9 0.6 0.0 1.0 2.0 0.5 1.5 0.1 0.7 0.0 3.2 0.9 3.2 0.2 2.4 0.0 0.5 0.7 0.4 0.2 0.1 1.0 0.3 9.8 0.2 1.4 0.0 1.5 0.1 1.3 1.3 1.5 1.5 0.3 1.0 1.6 0.8 4.3 0.3 1.4 0.5 10.5 1.1 0.0 0.3 4.7 0.0 8.1 4.3 0.6 0.1 0.6 2.3 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 OXSM "CEM1, FASN2D, FLJ20604, KS" ENSG00000151093 "3-oxoacyl-ACP synthase, mitochondrial" Q9NWU1 3 25782917-25794534 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021293, HPA021300, HPA021337" Enhanced Approved Mitochondria,Cytosol "Mitochondria, Cytosol" "HPA021293: AB_1848772, HPA021300: AB_1848774, HPA021337: AB_1848776" "unprognostic (2.20e-2)" "unprognostic (3.28e-1)" "prognostic favourable (1.35e-4)" "prognostic favourable (5.51e-4)" "unprognostic (1.01e-1)" "unprognostic (8.17e-2)" "unprognostic (2.15e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "unprognostic (2.83e-2)" "unprognostic (3.06e-2)" "unprognostic (1.20e-1)" "prognostic favourable (4.18e-9)" "unprognostic (1.79e-2)" "unprognostic (2.42e-1)" "unprognostic (3.10e-1)" "unprognostic (1.73e-2)" 6.2 13.7 6.7 9.8 10.5 3.7 10.3 8.3 11.9 6.0 11.8 6.2 13.7 10.1 6.4 16.2 10.3 7.7 7.9 13.5 6.6 6.4 14.9 26.1 10.0 7.7 6.6 6.5 6.4 18.7 8.3 13.0 7.3 7.0 8.0 13.8 10.4 15.5 15.6 19.4 8.3 8.9 5.8 6.7 9.6 8.9 19.9 8.0 8.1 11.7 12.3 11.3 7.9 6.4 8.4 9.0 3.7 6.5 10.3 11.8 6.6 7.6 12.9 2.7 7.6 8.0 8.8 7.9 6.2 9.0 11.6 8.3 9.8 9.2 14.3 8.4 5.6 8.1 11.3 11.8 11.0 8.5 11.5 15.7 10.9 11.8 9.8 12.7 10.0 8.2 14.8 9.3 9.7 10.0 16.1 11.6 9.8 11.5 9.2 9.8 0.5 14.8 12.4 7.2 23.3 17.1 4.8 3.9 7.2 9.8 16.9 12.6 18.5 11.8 6.1 7.3 8.7 9.5 8.9 11.1 12.7 4.5 10.3 11.2 7.4 2.1 5.4 3.7 9.4 6.0 10.8 8.4 9.7 11.6 8.6 8.2 11.4 11.8 0.9 10.3 6.5 9.0 6.0 6.6 6.7 10.5 8.3 11.9 6.6 6.4 6.6 6.5 7.0 8.0 OXSR1 "KIAA1101, OSR1" ENSG00000172939 "Oxidative stress responsive 1" O95747 3 38165089-38255488 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008237, CAB017181" Supported Enhanced Cytosol 21000000 Cytosol "CAB017181: , HPA008237: AB_1079540" "unprognostic (2.16e-1)" "unprognostic (2.36e-2)" "unprognostic (1.79e-2)" "unprognostic (4.55e-3)" "unprognostic (9.89e-2)" "unprognostic (1.97e-2)" "unprognostic (3.53e-3)" "unprognostic (4.05e-2)" "unprognostic (4.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.95e-3)" "unprognostic (1.88e-2)" "unprognostic (1.87e-3)" "unprognostic (1.56e-1)" "unprognostic (3.14e-2)" "unprognostic (1.71e-1)" "unprognostic (6.99e-3)" 17.6 16.8 9.4 18.3 13.4 24.2 15.9 17.4 14.9 16.8 15.4 9.2 35.7 12.4 14.9 14.7 31.6 11.6 18.9 15.5 11.9 9.0 18.3 17.6 14.6 13.9 13.6 9.3 16.7 12.3 23.7 15.3 21.4 12.3 16.5 16.8 13.0 15.1 23.9 32.6 17.4 21.4 17.0 12.9 15.8 14.0 11.2 13.2 26.2 14.2 24.1 19.6 23.5 19.2 2.3 4.4 10.1 4.8 5.0 4.7 1.6 17.5 8.0 16.1 11.2 11.2 13.0 18.3 15.6 21.4 22.5 24.5 10.3 11.5 19.5 7.9 18.6 10.9 21.6 16.0 29.8 20.6 8.8 21.3 17.1 11.3 13.5 13.1 13.0 10.3 18.9 20.8 33.7 14.0 16.1 11.2 38.5 4.9 25.3 9.5 16.9 9.6 8.8 13.5 15.0 13.9 13.4 8.4 12.9 17.0 43.2 10.6 14.2 8.6 12.7 14.2 14.1 21.5 23.0 8.6 10.2 14.3 19.4 16.4 28.2 10.1 2.8 6.1 3.3 4.8 3.5 1.9 4.0 3.1 4.4 2.3 3.0 3.7 5.5 5.0 4.1 2.5 4.7 1.6 9.4 13.4 17.4 14.9 11.9 9.0 13.6 9.3 12.3 13.2 P3H1 "GROS1, LEPRE1, LEPRECAN, MGC117314" ENSG00000117385 "Prolyl 3-hydroxylase 1" Q32P28 1 42746335-42767084 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA012113, HPA016980" Approved Approved Nucleoli,Vesicles "Intracellular and membrane" 13000 Vesicles Nucleoli "HPA012113: , HPA016980: AB_2669498" "unprognostic (3.24e-1)" "unprognostic (1.04e-1)" "unprognostic (9.37e-2)" "unprognostic (4.57e-1)" "unprognostic (2.03e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (4.95e-7)" "unprognostic (5.41e-2)" "unprognostic (2.70e-3)" "unprognostic (9.16e-2)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" "unprognostic (2.67e-2)" "unprognostic (1.60e-3)" 11.9 11.2 7.1 8.6 6.3 5.2 9.7 6.4 5.3 14.0 7.1 6.0 7.7 2.6 13.8 11.1 6.4 8.8 12.1 8.8 3.8 2.9 7.9 19.9 10.8 10.1 6.1 3.3 13.1 6.8 5.8 15.2 36.1 4.6 7.8 5.7 10.5 6.4 6.5 4.3 7.2 6.6 19.7 3.4 13.3 6.6 13.1 4.7 10.2 7.4 5.3 7.8 11.4 8.5 3.1 16.2 11.0 16.2 11.7 7.9 6.1 2.2 5.8 13.0 30.4 30.8 23.6 5.3 26.8 34.9 19.4 33.1 2.9 4.9 3.3 21.5 50.5 2.0 5.5 6.8 13.4 4.9 6.9 7.8 9.2 8.3 17.9 7.8 9.0 20.1 4.6 19.5 8.4 27.3 4.4 4.2 12.9 1.2 5.0 4.4 14.2 4.2 5.0 19.2 4.5 10.2 1.2 2.7 4.6 16.3 0.4 11.5 0.9 32.8 22.2 14.5 12.8 11.5 10.6 3.8 4.3 3.0 16.6 10.6 20.1 3.5 13.2 11.0 6.0 14.0 6.4 3.1 4.6 5.1 16.2 2.6 3.9 3.9 1.2 11.7 16.2 7.6 7.9 6.1 7.1 6.3 6.4 5.3 3.8 2.9 6.1 3.3 4.6 4.7 P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 74.5" "Cell line enhanced" "Detected in many" "HaCaT: 36.0;RPTEC TERT1: 36.7;RT4: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 22 "plasmacytoid DC: 20.3" "Lineage enriched" "Detected in single" 104 "dendritic cells: 20.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" "Golgi apparatus" Nucleoplasm "HPA007890: AB_1852796, HPA013355: AB_1852798, HPA013611: " "unprognostic (4.90e-2)" "unprognostic (1.57e-1)" "unprognostic (3.76e-1)" "unprognostic (4.32e-3)" "unprognostic (1.97e-2)" "unprognostic (7.75e-2)" "unprognostic (9.68e-2)" "unprognostic (2.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-2)" 2.4 22.6 2.9 4.0 3.9 0.2 3.1 0.7 2.2 14.3 11.8 6.2 11.5 1.2 15.0 13.5 8.9 4.6 8.4 3.8 2.8 2.1 74.5 3.5 22.5 3.6 8.1 1.0 11.2 3.9 1.4 6.1 11.0 5.6 19.9 5.3 10.3 2.7 14.3 0.6 8.6 3.6 16.3 7.6 33.7 12.0 2.8 5.3 2.0 1.7 6.3 2.7 5.7 9.8 0.0 20.3 0.1 0.1 0.0 0.0 0.1 14.9 5.9 11.7 0.0 0.2 0.4 14.0 15.9 6.3 2.6 4.2 4.8 5.9 0.0 9.1 2.8 36.0 0.0 21.3 5.5 0.1 2.0 0.0 4.0 0.0 12.1 0.0 0.1 5.7 7.2 5.0 1.8 0.4 0.0 0.1 4.0 0.3 0.0 0.1 3.6 1.2 0.0 2.3 0.8 36.7 25.1 0.8 0.1 21.6 1.2 9.5 0.0 0.2 7.9 15.5 5.8 0.1 2.8 1.1 0.0 0.1 3.6 0.0 19.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 20.3 0.0 0.1 2.9 3.9 0.7 2.2 2.8 2.1 8.1 1.0 5.6 5.3 P3H3 "GRCB, HSU47926, LEPREL2" ENSG00000110811 "Prolyl 3-hydroxylase 3" Q8IVL6 12 6828410-6839851 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 22.2;NTERA-2: 15.8;U-251 MG: 15.3" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in some" "MAIT T-cell: 2.1;naive CD4 T-cell: 1.7" "Lineage enriched" "Detected in single" 21 "T-cells: 2.1" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 17.6" HPA043695 Approved Approved "Nucleoli,Plasma membrane,Cytosol" "Intracellular and membrane" "Plasma membrane, Cytosol" Nucleoli "HPA043695: AB_10797146" "unprognostic (2.54e-1)" "unprognostic (6.66e-2)" "unprognostic (1.14e-1)" "unprognostic (3.34e-2)" "unprognostic (5.76e-2)" "unprognostic (6.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.92e-1)" "unprognostic (6.90e-2)" "unprognostic (1.44e-1)" "prognostic favourable (4.91e-4)" "unprognostic (1.29e-1)" "prognostic unfavourable (1.64e-4)" "unprognostic (2.58e-2)" "unprognostic (9.67e-2)" "unprognostic (2.27e-1)" "unprognostic (7.77e-3)" 3.7 3.1 1.2 2.2 2.6 0.3 3.0 10.7 2.5 12.1 2.7 0.0 7.6 1.1 11.0 8.5 2.5 2.1 5.6 4.4 1.2 1.1 0.4 1.6 1.9 0.0 2.2 9.3 3.6 12.1 7.4 2.5 0.8 5.6 0.5 8.1 5.9 6.5 0.5 1.8 1.7 8.8 0.5 1.0 2.8 2.1 0.1 0.0 3.5 1.2 1.4 5.9 4.7 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.9 4.2 8.0 4.9 6.0 0.1 22.2 12.8 7.1 7.8 0.3 0.0 0.0 0.3 8.3 0.0 2.5 0.2 1.6 0.0 10.6 0.5 2.3 1.0 3.5 0.5 0.0 6.5 0.2 3.4 1.9 7.4 2.0 0.0 3.3 0.0 0.0 0.2 15.8 0.6 0.0 3.9 0.1 0.3 0.0 1.6 6.0 0.0 0.0 2.5 0.1 0.1 13.0 6.9 10.3 10.6 15.3 0.0 0.1 0.2 5.9 0.0 2.7 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.9 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 P4HA1 "C-P4Halpha(I), P4HA" ENSG00000122884 "Prolyl 4-hydroxylase subunit alpha 1" P13674 10 73007217-73096974 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 105.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007599, HPA026593" Enhanced Supported "Endoplasmic reticulum,Vesicles,Mitochondria" "Intracellular and membrane" "Endoplasmic reticulum" "Vesicles, Mitochondria" "HPA007599: AB_1854891, HPA026593: AB_1854892" "prognostic unfavourable (9.01e-4)" "prognostic unfavourable (3.19e-5)" "unprognostic (2.76e-3)" "unprognostic (3.04e-1)" "unprognostic (1.69e-2)" "prognostic unfavourable (1.19e-5)" "unprognostic (2.30e-1)" "prognostic unfavourable (5.10e-4)" "unprognostic (1.28e-1)" "unprognostic (2.29e-1)" "prognostic unfavourable (2.85e-4)" "unprognostic (9.15e-2)" "prognostic unfavourable (9.40e-9)" "unprognostic (3.14e-1)" "unprognostic (4.22e-2)" "unprognostic (1.02e-2)" "unprognostic (5.75e-2)" 16.8 14.4 16.5 10.4 20.2 7.0 47.6 9.9 18.2 18.5 10.9 11.3 7.4 5.6 14.8 12.2 11.6 22.4 14.1 23.9 17.0 10.9 19.0 39.9 18.1 7.5 33.5 4.9 22.3 13.1 11.1 8.6 33.5 25.4 17.9 9.4 8.6 8.5 10.4 63.5 10.3 7.8 15.1 45.8 9.7 11.1 9.7 30.9 4.1 19.4 7.5 7.3 34.4 105.7 6.9 14.8 10.2 17.3 3.4 7.3 6.1 17.3 4.5 13.0 25.3 40.2 30.9 10.9 51.0 46.2 19.7 47.4 7.4 13.5 5.9 19.5 50.4 19.7 8.2 18.6 43.3 7.5 3.1 5.0 4.3 8.8 16.7 9.2 3.5 18.7 10.9 16.8 22.3 9.3 7.8 3.1 17.0 4.6 3.6 8.9 4.6 19.8 3.4 8.7 10.6 11.1 7.5 1.2 7.3 10.4 30.8 12.1 4.7 8.7 8.8 24.2 10.0 6.7 11.8 17.7 6.4 2.8 43.4 13.5 11.7 0.8 13.5 10.2 5.2 16.4 6.7 6.0 6.2 6.0 14.8 6.9 4.6 4.7 7.4 3.4 17.3 11.8 7.3 6.1 16.5 20.2 9.9 18.2 17.0 10.9 33.5 4.9 25.4 30.9 P4HA2 C-P4Halpha(II) ENSG00000072682 "Prolyl 4-hydroxylase subunit alpha 2" O15460 5 132191838-132295315 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 61.3;U-87 MG: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016997, HPA027824, CAB062557" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" "Endoplasmic reticulum, Vesicles" "CAB062557: , HPA016997: AB_2669501, HPA027824: AB_2672402" "unprognostic (1.30e-3)" "prognostic unfavourable (1.24e-5)" "unprognostic (2.56e-3)" "unprognostic (1.28e-3)" "unprognostic (2.08e-3)" "unprognostic (1.62e-3)" "unprognostic (1.16e-3)" "unprognostic (1.93e-3)" "unprognostic (2.83e-2)" "unprognostic (1.92e-1)" "unprognostic (8.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavourable (2.77e-7)" "unprognostic (2.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.23e-1)" "prognostic unfavourable (3.12e-4)" 10.2 5.6 7.1 6.5 5.4 0.8 12.2 9.5 7.8 14.4 12.5 4.6 6.1 9.8 20.0 35.3 11.6 13.7 9.7 26.1 6.6 7.0 34.4 6.3 16.0 4.3 6.3 4.2 6.7 42.5 6.7 15.8 15.1 9.5 9.3 14.6 15.1 21.1 8.4 7.1 9.3 17.1 23.3 5.1 6.3 12.6 5.1 4.4 4.1 12.2 10.8 5.4 11.3 34.5 0.2 1.0 3.1 1.3 2.6 2.6 0.7 10.1 6.2 2.0 9.9 27.9 33.3 11.3 47.5 40.6 20.2 50.0 14.0 8.9 0.2 14.0 50.8 12.8 6.2 24.8 32.0 7.5 2.1 0.0 9.1 8.4 61.3 0.0 6.1 20.1 36.7 23.9 22.0 10.6 3.6 0.6 24.7 4.0 0.0 0.0 0.5 5.1 0.1 0.6 1.5 5.6 1.9 1.0 2.8 12.1 4.0 8.0 5.0 0.7 16.3 30.7 12.0 9.3 10.2 4.3 4.6 2.0 59.2 0.0 8.5 0.0 1.3 0.0 2.6 1.1 2.4 0.0 1.4 0.4 0.6 0.2 0.0 0.4 3.1 2.6 0.2 1.0 0.0 0.7 7.1 5.4 9.5 7.8 6.6 7.0 6.3 4.2 9.5 4.4 P4HA3 C-P4Halpha(III) ENSG00000149380 "Prolyl 4-hydroxylase subunit alpha 3" Q7Z4N8 11 74235801-74311657 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 22.6" "Cell line enhanced" "Detected in some" "BJ: 12.6;fHDF/TERT166: 6.1;HSkMC: 6.1;HUVEC TERT2: 24.8;TIME: 17.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA007897 Approved "Intracellular and membrane" "HPA007897: AB_2156427" "unprognostic (2.74e-2)" "unprognostic (1.37e-4)" "unprognostic (1.31e-3)" "unprognostic (3.19e-2)" "unprognostic (2.54e-4)" "unprognostic (9.65e-3)" "unprognostic (4.34e-2)" "unprognostic (3.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.21e-3)" "unprognostic (1.38e-2)" "unprognostic (8.31e-2)" "prognostic unfavourable (3.34e-9)" "unprognostic (1.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.05e-2)" "prognostic unfavourable (7.83e-4)" 3.0 1.2 0.1 4.7 0.5 0.0 1.3 2.1 0.4 2.5 2.3 0.4 2.8 0.3 7.1 22.6 0.7 1.9 7.5 1.1 0.4 0.2 0.9 1.7 2.2 0.9 0.1 0.0 3.8 0.3 0.0 5.7 7.4 1.1 9.8 0.9 6.4 2.0 6.1 1.1 0.5 1.0 13.7 0.4 0.2 0.7 2.3 0.0 0.0 4.1 1.6 0.4 9.7 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.0 4.2 0.4 0.0 12.6 0.9 0.6 1.4 0.0 0.0 0.0 1.2 6.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.7 0.0 5.4 0.0 0.0 6.1 0.0 4.3 0.5 24.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 17.6 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 2.1 0.4 0.4 0.2 0.1 0.0 1.1 0.0 P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860694 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 383.4;pancreas: 677.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" 140000000 "Endoplasmic reticulum" "CAB012463: , HPA018884: AB_1854896" "unprognostic (9.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.99e-2)" "unprognostic (7.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (4.73e-3)" "unprognostic (1.43e-1)" "unprognostic (3.93e-2)" "prognostic unfavourable (2.30e-11)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (4.99e-3)" "unprognostic (3.19e-3)" 18.0 34.7 6.3 15.4 8.4 35.0 16.1 6.1 6.5 22.1 40.5 9.0 45.0 42.6 14.7 29.1 40.3 12.8 42.3 20.7 6.3 5.9 27.2 383.4 20.9 29.1 7.9 4.5 14.3 677.5 6.4 23.4 58.5 7.2 22.5 8.5 12.3 251.9 42.5 31.0 24.3 112.8 11.0 5.2 36.7 31.6 9.1 7.2 10.5 29.7 50.7 46.4 16.5 20.5 21.6 71.3 45.8 60.8 38.8 55.9 70.8 57.7 50.3 18.6 60.0 50.4 59.3 44.2 112.8 72.8 49.2 66.6 36.9 50.6 23.3 49.6 72.5 41.0 20.5 44.1 28.5 15.0 34.7 34.9 52.9 150.1 66.3 110.1 57.7 44.7 30.0 39.3 41.7 81.0 24.7 100.7 35.0 52.7 31.5 87.5 14.6 45.8 25.8 33.3 46.2 38.2 69.8 22.4 24.8 56.2 162.4 58.5 73.4 129.7 62.9 92.4 46.3 52.4 55.0 72.4 52.4 22.0 121.4 42.4 70.4 45.8 60.8 38.3 53.5 38.7 55.9 21.6 36.4 42.8 43.4 18.7 21.2 31.5 20.0 38.8 27.6 71.3 25.7 70.8 6.3 8.4 6.1 6.5 6.3 5.9 7.9 4.5 7.2 7.2 PA2G4 ENSG00000170515 "Proliferation-associated 2G4" Q9UQ80 12 56104319-56113907 "Enzymes, Plasma proteins, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation, Translation regulation" "Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB011711, CAB012428, HPA016484" Supported Approved Cytosol 1200000 Cytosol "CAB011711: AB_732060, CAB012428: , HPA016484: AB_1854912" "unprognostic (5.53e-2)" "unprognostic (1.06e-1)" "unprognostic (2.35e-2)" "unprognostic (2.34e-2)" "unprognostic (3.87e-1)" "unprognostic (6.03e-3)" "prognostic unfavourable (6.31e-7)" "unprognostic (4.25e-3)" "unprognostic (2.77e-1)" "unprognostic (3.79e-3)" "unprognostic (2.29e-2)" "unprognostic (1.30e-2)" "prognostic unfavourable (4.59e-7)" "unprognostic (1.17e-1)" "unprognostic (2.01e-1)" "unprognostic (1.32e-1)" "unprognostic (4.67e-2)" 41.1 32.1 26.6 41.4 29.8 52.5 38.5 35.1 38.8 33.7 39.2 31.0 27.1 34.4 36.1 22.4 69.4 31.2 31.9 55.6 26.6 25.5 36.1 51.6 32.6 43.3 26.7 28.0 43.3 44.3 42.8 20.5 39.0 28.2 40.3 44.2 23.6 34.6 33.4 77.3 53.0 31.7 39.4 32.3 46.7 34.4 27.9 23.9 70.8 39.7 57.2 54.0 45.5 39.6 25.5 27.1 13.5 25.1 37.4 48.9 36.0 53.3 47.4 32.6 35.8 15.1 22.9 65.4 56.5 27.1 69.6 38.8 57.9 39.7 106.8 38.1 26.7 44.0 74.2 63.1 68.0 30.3 63.6 82.1 32.3 49.4 29.5 111.3 30.4 23.1 32.3 60.2 54.5 42.2 99.6 49.7 38.1 47.3 86.5 58.2 53.4 58.3 71.3 58.9 72.4 35.2 40.1 48.9 29.6 37.2 58.9 34.5 63.5 43.3 33.8 34.0 48.0 39.1 62.4 30.5 41.9 104.6 30.7 67.1 44.0 7.8 23.0 13.5 36.6 25.1 48.9 25.5 38.9 39.4 27.1 22.2 37.6 37.3 3.7 37.4 20.0 26.3 43.3 36.0 26.6 29.8 35.1 38.8 26.6 25.5 26.7 28.0 28.2 23.9 PADI1 "HPAD10, PAD1, PDI, PDI1" ENSG00000142623 "Peptidyl arginine deiminase 1" Q9ULC6 1 17205126-17246005 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 48.7;lymphoid tissue: 60.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.3;EFO-21: 4.5;HaCaT: 2.8;LHCN-M2: 3.6;RPTEC TERT1: 4.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory region: 0.5" "Low region specificity" "Detected in some" HPA062294 Enhanced Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA062294: " "unprognostic (9.30e-2)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.40e-1)" "unprognostic (5.22e-2)" "unprognostic (7.27e-2)" "unprognostic (3.84e-1)" "unprognostic (3.37e-2)" "unprognostic (1.41e-1)" "unprognostic (7.75e-2)" "unprognostic (1.01e-3)" "unprognostic (3.64e-2)" "prognostic unfavourable (8.34e-11)" "unprognostic (2.00e-1)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.3 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.1 0.0 4.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.1 60.2 1.3 6.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.2 0.0 0.1 9.3 0.0 4.5 0.4 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119435 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 76.7;skeletal muscle: 126.4" "Cell line enhanced" "Detected in some" "A549: 6.8;RPTEC TERT1: 19.9;SK-BR-3: 30.4;T-47d: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 15.1;neutrophil: 37.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced "HPA047735: " "unprognostic (2.61e-2)" "unprognostic (3.60e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (3.74e-3)" "unprognostic (2.78e-3)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-3)" 2.1 1.4 16.2 5.0 25.1 10.9 19.2 3.3 25.6 2.7 41.4 76.7 1.3 1.6 1.4 1.3 3.8 2.3 1.8 1.1 21.9 15.6 5.5 1.3 2.2 1.4 36.8 13.6 1.1 1.7 1.3 1.5 1.6 45.6 2.3 43.4 4.6 21.1 1.8 126.4 2.8 3.6 3.9 69.6 4.2 2.1 1.3 26.0 0.0 1.2 14.8 1.6 2.1 0.7 0.0 4.2 37.2 5.1 0.0 0.0 1.7 0.0 6.8 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 2.9 0.1 0.9 0.3 0.9 0.2 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 2.2 0.3 0.8 0.9 0.0 0.0 0.0 0.2 19.9 0.0 1.2 0.1 0.0 30.4 0.0 8.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.4 5.1 15.1 0.0 0.3 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 37.2 0.0 0.1 0.1 0.0 1.7 16.2 25.1 3.3 22.0 21.9 15.6 36.8 13.6 45.6 26.0 PADI3 PDI3 ENSG00000142619 "Peptidyl arginine deiminase 3" Q9ULW8 1 17249098-17284233 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 10.5;smooth muscle: 9.4;urinary bladder: 28.0" "Cell line enhanced" "Detected in some" "EFO-21: 13.2;RT4: 15.8;T-47d: 11.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 48.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043739 Uncertain Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA043739: AB_10959466" "unprognostic (4.47e-2)" "unprognostic (9.32e-2)" "unprognostic (1.50e-1)" "prognostic unfavourable (3.22e-4)" "unprognostic (1.05e-3)" "unprognostic (6.66e-2)" "unprognostic (3.10e-3)" "unprognostic (5.88e-2)" "unprognostic (2.06e-4)" "unprognostic (1.03e-1)" "unprognostic (3.47e-4)" "unprognostic (1.76e-1)" "prognostic unfavourable (1.55e-11)" "unprognostic (2.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.64e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.1 0.0 0.0 3.2 10.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.6 6.4 0.0 2.3 0.0 9.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 28.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 13.2 0.0 0.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 15.8 0.0 0.0 0.0 2.3 0.1 11.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PADI4 "PAD, PADI5, PDI4, PDI5" ENSG00000159339 "Peptidyl arginine deiminase 4" Q9UM07 1 17308195-17364004 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood: 48.2;bone marrow: 54.8;lymphoid tissue: 24.2" "Cell line enhanced" "Detected in some" "BEWO: 1.7;HEL: 4.1;NB-4: 1.6;RPMI-8226: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "basophil: 17.0;classical monocyte: 18.6;eosinophil: 24.6;neutrophil: 48.2" "Group enriched" "Detected in many" 9 "granulocytes: 48.2;monocytes: 18.6" "Not detected" "Not detected" "HPA017007, HPA042825" Enhanced 12000 "HPA017007: AB_1854921, HPA042825: AB_2678189" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (1.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-2)" "unprognostic (8.49e-2)" "unprognostic (5.22e-2)" "unprognostic (8.55e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" 1.2 0.2 0.3 0.5 0.2 54.8 0.2 0.1 0.8 0.2 0.2 0.5 0.0 0.2 0.2 0.1 0.4 0.9 0.4 9.8 0.6 0.1 0.3 1.2 9.7 5.2 1.8 0.0 0.9 0.3 0.1 0.6 4.1 0.6 0.1 0.2 0.9 0.5 0.1 0.2 0.2 0.2 0.4 0.2 24.2 0.3 1.0 0.3 2.6 0.6 0.2 0.2 0.4 7.5 0.4 3.6 48.2 18.6 1.1 1.2 8.1 0.2 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 4.1 0.1 0.4 0.0 0.4 0.5 0.0 0.5 0.1 0.0 0.1 0.6 0.2 0.0 0.0 0.0 1.6 0.2 0.2 0.2 0.0 4.8 0.0 0.3 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.1 0.0 0.2 0.5 0.1 17.0 18.6 24.6 0.1 1.4 0.0 0.2 0.1 0.2 3.6 0.4 0.7 1.2 48.2 1.1 0.4 1.6 0.1 8.1 0.3 0.2 0.1 0.8 0.6 0.1 1.8 0.0 0.6 0.3 PAFAH1B2 ENSG00000168092 "Platelet activating factor acetylhydrolase 1b catalytic subunit 2" P68402 11 117144267-117176894 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051836 Approved Supported "Nucleoli,Plasma membrane,Cytosol" 1600000 Cytosol "Nucleoli, Plasma membrane" "HPA051836: " "unprognostic (1.08e-2)" "unprognostic (3.14e-2)" "unprognostic (2.07e-2)" "unprognostic (3.88e-2)" "unprognostic (9.94e-2)" "unprognostic (1.21e-3)" "prognostic unfavourable (9.44e-4)" "prognostic unfavourable (3.07e-4)" "unprognostic (1.01e-1)" "prognostic favourable (4.25e-4)" "prognostic unfavourable (7.79e-5)" "unprognostic (8.18e-2)" "unprognostic (1.11e-2)" "unprognostic (9.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" 21.5 34.1 30.6 19.2 29.7 33.5 32.3 43.5 41.3 21.6 20.2 33.3 12.7 21.1 23.4 22.8 23.3 20.8 19.3 26.2 31.9 36.8 24.6 22.5 20.5 17.7 39.3 31.6 23.6 23.0 23.1 24.2 26.9 39.6 22.2 19.6 17.3 19.3 17.4 14.1 20.8 18.0 19.9 51.6 18.3 21.4 29.9 26.3 15.1 30.9 10.8 20.4 25.9 20.3 26.8 21.6 36.8 35.7 18.9 31.4 26.9 14.8 17.0 19.7 28.3 22.0 15.4 15.3 25.0 21.9 13.9 12.7 31.0 32.8 16.1 35.9 29.9 23.9 28.5 32.3 18.4 14.3 11.0 41.3 15.6 19.9 19.7 14.2 15.8 17.0 25.6 27.8 35.1 22.8 21.9 12.3 21.3 9.5 13.7 21.0 18.0 13.4 15.4 22.3 17.6 21.3 23.3 21.9 29.1 28.8 21.8 9.5 24.3 12.3 36.4 25.5 16.9 12.4 17.7 3.9 5.9 21.6 10.3 27.4 21.4 32.1 30.8 26.7 24.2 33.3 28.2 26.8 28.0 25.3 21.6 25.4 29.3 31.4 36.8 18.9 35.7 15.8 19.5 26.9 30.6 29.7 43.5 37.8 31.9 36.8 39.3 31.6 39.6 26.3 PAFAH1B3 ENSG00000079462 "Platelet activating factor acetylhydrolase 1b catalytic subunit 3" Q15102 19 42297033-42303546 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035639 Uncertain Approved "Intermediate filaments" 370000 "Intermediate filaments" "HPA035639: AB_10670163" "unprognostic (3.19e-1)" "unprognostic (5.38e-3)" "unprognostic (1.13e-1)" "unprognostic (5.99e-2)" "unprognostic (1.83e-1)" "unprognostic (2.09e-2)" "prognostic unfavourable (8.74e-4)" "unprognostic (1.73e-1)" "unprognostic (2.67e-1)" "unprognostic (6.36e-2)" "unprognostic (2.37e-1)" "unprognostic (7.67e-2)" "prognostic unfavourable (2.07e-4)" "unprognostic (2.68e-1)" "unprognostic (3.21e-2)" "unprognostic (4.56e-2)" "unprognostic (6.80e-3)" 4.5 12.8 23.8 10.4 23.2 20.7 12.2 36.4 24.9 17.2 14.6 7.8 8.0 10.9 10.1 11.9 15.5 13.5 9.6 4.6 15.4 25.7 11.7 5.6 5.8 13.6 13.9 13.1 15.4 11.9 8.3 11.8 5.8 12.4 10.3 10.7 11.2 9.8 6.1 10.8 10.6 11.2 6.6 11.7 9.5 11.3 16.3 11.3 37.4 7.8 13.8 15.4 14.6 10.9 19.6 24.6 8.7 13.6 7.8 27.4 10.5 29.4 54.0 33.7 36.0 0.7 1.8 10.4 7.4 10.3 24.4 25.3 17.9 24.8 18.2 9.7 9.0 10.0 15.3 19.5 10.2 27.5 20.9 22.0 14.5 24.0 5.2 13.9 24.5 5.3 9.0 14.9 7.0 10.8 15.5 21.7 17.7 43.0 31.1 10.9 18.7 0.0 23.1 12.9 16.2 19.8 31.1 38.8 30.4 11.8 23.5 12.4 29.3 16.0 5.8 20.3 27.4 1.8 20.0 10.4 21.4 15.5 11.3 22.6 17.8 8.7 13.6 7.2 12.1 10.7 16.1 19.6 17.3 13.9 24.6 18.4 23.0 16.0 1.8 7.8 5.4 13.6 27.4 10.5 23.8 23.2 36.4 24.9 15.4 25.7 13.9 13.1 12.4 11.3 PAFAH2 HSD-PLA2 ENSG00000158006 "Platelet activating factor acetylhydrolase 2" Q99487 1 25959767-25998157 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 33.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018157 Approved "HPA018157: AB_1854928" "unprognostic (9.89e-2)" "unprognostic (2.60e-1)" "unprognostic (3.63e-3)" "prognostic favourable (3.28e-6)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (4.46e-2)" "unprognostic (2.62e-1)" "prognostic favourable (0.00e+0)" "unprognostic (8.15e-2)" "unprognostic (8.17e-2)" "unprognostic (1.59e-2)" "unprognostic (7.27e-2)" 6.5 8.8 8.9 6.3 11.0 4.1 7.0 10.7 9.0 7.0 12.3 11.9 7.8 13.2 5.7 7.7 8.7 6.4 10.1 6.7 8.0 4.5 15.5 20.9 6.3 5.5 10.7 5.1 4.7 34.7 14.8 13.6 7.8 9.8 6.8 13.0 9.6 9.0 5.0 19.3 9.5 25.3 5.2 9.8 7.9 11.6 8.4 11.1 4.4 13.6 6.3 11.4 6.5 6.3 2.4 18.9 28.0 3.3 8.3 12.3 3.9 5.2 6.7 4.3 4.8 8.9 7.1 8.8 6.0 3.1 5.5 3.7 2.7 11.3 2.3 7.5 3.5 4.7 6.4 5.8 7.1 4.8 3.8 3.9 2.9 5.3 5.4 2.0 33.7 4.6 13.3 8.4 5.6 5.2 5.3 4.5 7.3 2.3 6.2 1.9 8.5 3.7 5.2 4.0 5.3 8.7 1.9 5.1 4.4 3.6 4.8 11.0 8.1 3.6 4.8 3.8 4.8 7.9 4.7 8.4 10.8 3.0 8.1 8.1 12.7 12.7 3.3 28.0 12.3 3.1 7.8 1.8 4.3 7.9 2.4 2.4 5.6 7.9 3.0 8.3 1.1 18.9 4.3 3.9 8.9 11.0 10.7 9.0 8.0 4.5 10.7 5.1 9.8 11.1 PAH PH ENSG00000171759 "Phenylalanine hydroxylase" P00439 12 102836885-102958410 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Phenylalanine catabolism" "Allosteric enzyme, Monooxygenase, Oxidoreductase" "Disease mutation, FDA approved drug targets, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "kidney: 65.1;liver: 220.0" "Cell line enriched" "Detected in some" 31 "Hep G2: 71.1" "Cancer enriched" "Detected in some" 17 "liver cancer: 94.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA028407, HPA031642" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Endoplasmic reticulum, Vesicles" "HPA028407: AB_10601241, HPA031642: AB_2673974" "unprognostic (1.16e-1)" "unprognostic (1.52e-1)" "unprognostic (4.47e-2)" "unprognostic (9.13e-3)" "unprognostic (5.19e-2)" "unprognostic (5.99e-2)" "prognostic favourable (4.30e-4)" "unprognostic (1.27e-1)" "unprognostic (6.60e-2)" "unprognostic (4.45e-3)" "unprognostic (1.94e-3)" "unprognostic (1.83e-1)" "unprognostic (1.10e-2)" "unprognostic (3.51e-1)" "unprognostic (1.64e-1)" "unprognostic (3.96e-2)" "unprognostic (1.68e-2)" 0.1 1.3 0.5 0.0 0.5 0.0 0.1 0.2 1.0 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.1 20.3 0.1 0.8 0.3 65.1 220.0 0.0 0.0 0.3 0.7 0.1 1.7 0.0 1.6 0.0 0.8 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 2.8 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 1.0 0.8 0.3 0.3 0.7 0.8 0.4 PAICS "ADE2H1, AIRC, PAIS" ENSG00000128050 "Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase" P22234 4 56435741-56464579 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Decarboxylase, Ligase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035895, HPA041538" Uncertain Approved Cytosol 340000 Cytosol "HPA035895: AB_10669660, HPA041538: AB_2677540" "unprognostic (2.59e-3)" "unprognostic (7.90e-3)" "unprognostic (3.84e-3)" "unprognostic (2.88e-2)" "unprognostic (9.85e-2)" "unprognostic (2.82e-3)" "prognostic unfavourable (1.50e-4)" "unprognostic (8.07e-3)" "unprognostic (1.23e-2)" "prognostic favourable (8.44e-4)" "unprognostic (1.48e-3)" "unprognostic (2.05e-1)" "prognostic unfavourable (5.85e-5)" "unprognostic (7.11e-2)" "unprognostic (1.67e-1)" "prognostic unfavourable (2.41e-4)" "unprognostic (2.16e-1)" 15.5 27.1 21.6 20.4 17.4 21.4 29.3 15.8 20.6 17.5 22.5 18.5 18.4 17.2 19.6 12.6 29.0 19.6 11.4 13.4 16.7 22.6 26.5 63.7 11.3 25.6 26.4 19.2 23.3 27.7 26.2 17.9 24.3 29.8 17.5 30.5 13.1 15.7 16.8 23.8 20.0 16.1 19.4 23.5 19.8 12.8 18.3 15.9 44.9 17.8 26.8 33.1 18.7 18.9 13.7 12.8 3.2 6.4 10.9 14.4 6.7 33.9 25.5 52.8 32.6 11.3 25.6 45.5 29.5 21.4 42.3 41.8 40.5 40.5 78.8 34.3 19.7 21.0 83.2 42.8 72.7 15.7 29.3 42.8 39.1 44.8 21.7 76.0 19.1 21.6 31.1 44.9 34.0 34.7 73.8 29.4 36.4 22.7 87.3 38.1 60.4 32.0 70.9 22.6 51.8 40.1 23.9 56.7 33.9 29.0 40.6 17.8 26.8 24.4 18.6 33.6 43.9 33.0 60.2 20.8 17.8 82.9 35.4 55.7 36.9 3.2 3.7 0.3 4.1 6.4 11.8 13.7 11.5 7.3 11.4 8.9 14.4 12.1 0.9 10.9 4.8 12.8 8.3 6.7 21.6 17.4 15.8 20.6 16.7 22.6 26.4 19.2 29.8 15.9 PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77321707-77474635 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 70.0;brain: 71.4" "Cell line enhanced" "Detected in many" "U-266/70: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 29.3;eosinophil: 45.0;intermediate monocyte: 28.7;myeloid DC: 42.3;neutrophil: 70.0;non-classical monocyte: 30.4" "Group enriched" "Detected in all" 11 "dendritic cells: 42.3;granulocytes: 70.0;monocytes: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" 200000 "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favourable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavourable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" 5.4 6.0 30.5 13.8 39.5 22.9 7.8 49.1 71.4 9.8 18.2 8.4 2.3 18.2 9.1 13.3 9.9 9.8 13.2 5.3 19.0 16.9 11.3 6.0 6.9 7.5 12.8 40.6 10.4 9.2 11.8 10.8 11.9 39.2 12.2 20.2 5.4 10.4 8.8 34.0 6.7 18.9 11.6 7.8 11.7 17.1 11.1 6.6 7.6 17.7 3.9 9.4 10.5 10.4 2.7 42.3 70.0 30.4 4.3 2.4 12.2 11.8 8.0 17.4 7.8 7.1 11.9 13.9 13.6 9.7 12.9 15.2 11.4 15.9 10.6 5.0 11.7 6.1 12.1 14.4 20.4 12.2 9.8 11.2 5.4 0.7 4.7 18.9 16.6 8.8 8.7 15.1 22.5 3.0 7.4 18.7 23.4 0.8 12.0 8.7 25.7 6.9 18.5 22.5 0.4 3.3 9.9 7.5 7.4 7.3 3.1 5.7 13.9 8.6 0.2 8.6 14.9 45.9 11.3 51.4 26.4 7.0 7.2 12.6 9.3 0.3 29.3 45.0 1.9 28.7 1.5 2.7 1.4 1.8 42.3 1.9 1.3 2.4 70.0 4.3 30.4 3.6 1.1 12.2 30.5 39.5 49.1 71.4 19.0 16.9 12.8 40.6 39.2 6.6 PAK2 "PAK65, PAKgamma" ENSG00000180370 "P21 (RAC1) activated kinase 2" Q13177 3 196739857-196832647 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Growth regulation, Host-virus interaction" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007794 Approved Approved Nucleoplasm,Vesicles 590000 "Nucleoplasm, Vesicles" "CAB007794: AB_562363" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" "unprognostic (2.52e-1)" "unprognostic (2.50e-2)" "unprognostic (1.32e-1)" "unprognostic (1.80e-1)" "unprognostic (5.18e-3)" "unprognostic (1.85e-2)" "unprognostic (7.97e-2)" "unprognostic (1.09e-1)" "prognostic unfavourable (3.36e-4)" "prognostic unfavourable (9.58e-4)" "unprognostic (1.30e-3)" "unprognostic (4.57e-2)" "unprognostic (1.25e-2)" "unprognostic (1.70e-2)" "unprognostic (3.39e-1)" 28.7 18.9 22.4 27.6 23.5 21.4 56.5 17.4 20.7 19.5 23.0 27.8 17.4 19.0 22.6 19.2 23.4 17.9 20.7 29.0 22.6 22.0 19.5 34.3 35.7 50.2 26.8 13.5 19.9 16.6 30.5 13.0 27.6 22.8 17.7 23.0 12.9 19.6 21.2 34.2 16.3 25.2 23.0 32.1 34.6 18.4 15.9 24.8 44.9 16.9 19.1 31.9 24.1 32.7 6.6 13.7 25.9 12.6 6.6 10.8 7.0 35.2 12.6 17.8 13.0 12.6 16.7 26.4 17.9 14.8 19.5 17.8 29.9 18.1 22.6 51.2 18.1 18.1 18.8 17.0 30.2 10.1 9.1 33.5 14.5 23.5 25.6 32.5 32.2 13.3 14.0 17.4 37.1 19.2 16.1 28.2 18.9 37.2 30.9 16.8 10.6 19.0 28.3 10.1 20.5 17.0 24.8 10.4 11.8 23.9 16.9 13.5 59.3 23.6 19.8 16.2 9.0 16.9 26.3 19.2 33.9 55.7 13.4 32.6 15.3 16.5 10.3 24.5 6.3 12.6 8.5 6.4 7.3 7.1 13.7 6.6 5.4 6.3 25.9 6.6 10.8 5.1 10.8 7.0 22.4 23.5 17.4 20.7 22.6 22.0 26.8 13.5 22.8 24.8 PAK3 "bPAK, hPAK3, MRX30, MRX47" ENSG00000077264 "P21 (RAC1) activated kinase 3" O75914 X 110944285-111227361 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Allosteric enzyme, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 26.2;pancreas: 46.5;pituitary gland: 37.2" "Cell line enhanced" "Detected in some" "EFO-21: 9.7;HAP1: 8.7;HDLM-2: 10.9;NTERA-2: 8.5;SCLC-21H: 11.1;SH-SY5Y: 6.9;U-2197: 6.7;U-251 MG: 11.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "MAIT T-cell: 4.3" "Lineage enriched" "Detected in single" 7 "T-cells: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044791, HPA060219" Approved Approved Cytosol Cytosol "HPA044791: , HPA060219: " "unprognostic (1.80e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "unprognostic (3.27e-4)" "unprognostic (2.46e-1)" "unprognostic (5.63e-3)" "unprognostic (7.29e-2)" "unprognostic (3.23e-2)" "unprognostic (1.27e-2)" "unprognostic (3.01e-1)" "unprognostic (6.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.89e-4)" "unprognostic (5.71e-3)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" 2.0 6.8 17.6 2.5 17.5 1.0 6.4 1.8 24.6 3.7 1.6 0.9 9.1 1.0 6.8 7.6 1.7 3.7 2.6 1.2 26.2 20.8 1.6 1.1 1.8 2.5 7.9 21.9 7.9 46.5 0.9 37.2 1.6 12.9 4.8 1.7 1.4 3.0 7.1 2.4 2.0 1.4 6.1 5.8 2.9 3.0 3.6 1.9 0.0 7.7 0.0 1.7 2.0 1.5 0.1 0.1 0.6 0.1 0.2 4.3 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 0.0 0.0 0.0 9.7 1.0 0.0 8.7 0.5 1.2 10.9 0.3 0.0 1.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 2.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 8.5 1.9 0.1 4.0 0.0 0.8 0.0 11.1 6.9 0.0 0.4 0.0 0.0 0.0 0.0 0.6 4.3 6.7 11.6 0.0 0.1 0.1 1.2 0.0 0.1 0.6 0.1 0.1 0.1 0.0 4.3 0.0 0.7 0.4 0.0 0.1 0.1 0.1 0.5 0.2 0.1 0.1 0.3 0.0 17.6 17.5 1.8 18.5 26.2 20.8 7.9 21.9 12.9 1.9 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 44.6;MCF7: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavourable (9.85e-4)" "prognostic favourable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 6.8 11.1 11.0 12.7 12.3 4.8 11.9 13.7 12.4 17.3 19.6 13.7 19.9 26.0 12.2 17.3 20.1 15.3 16.5 8.1 10.9 8.1 19.4 17.0 18.7 5.4 13.7 7.7 13.8 29.6 11.2 17.0 23.0 10.3 29.6 8.1 19.7 40.9 18.5 10.3 18.6 25.1 9.0 8.3 7.9 18.6 22.3 12.5 8.8 15.2 10.1 14.7 11.5 15.0 2.8 3.4 4.2 2.5 3.6 4.5 1.9 17.6 44.6 6.6 10.1 2.1 2.2 20.1 8.4 3.4 5.7 5.7 29.2 15.0 4.0 12.8 5.3 6.5 3.6 6.7 2.1 10.7 10.2 4.8 8.1 14.2 3.4 4.8 7.0 2.7 3.0 5.3 3.8 7.4 9.5 3.2 3.4 49.1 5.1 5.3 12.1 10.7 5.2 5.2 3.0 5.5 19.4 21.3 14.7 8.6 38.3 9.5 17.0 8.0 12.3 9.7 16.7 11.1 15.0 3.6 3.4 3.3 11.9 2.9 11.6 1.0 2.5 4.2 2.6 1.4 3.6 2.2 2.9 4.5 3.4 2.8 2.2 2.2 2.1 3.6 2.1 2.9 3.0 1.9 11.0 12.3 13.7 12.4 10.9 8.1 13.7 7.7 10.3 12.5 PAK5 "KIAA1264, PAK7" ENSG00000101349 "P21 (RAC1) activated kinase 5" Q9P286 20 9537389-9839041 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 30.3" "Group enriched" "Detected in some" 9 "SCLC-21H: 10.0;SH-SY5Y: 3.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020444 Approved Approved Nucleoplasm Nucleoplasm "HPA020444: AB_1854947" "unprognostic (5.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.05e-1)" "unprognostic (8.63e-2)" "unprognostic (3.21e-1)" "unprognostic (3.04e-1)" "unprognostic (2.25e-4)" "unprognostic (3.76e-1)" "unprognostic (2.56e-2)" "unprognostic (3.83e-1)" "unprognostic (3.35e-2)" "unprognostic (6.04e-2)" "unprognostic (4.58e-1)" 0.5 5.2 5.7 0.6 11.7 0.5 1.6 30.3 19.6 0.8 0.6 0.8 0.0 0.7 1.0 2.2 1.0 0.7 3.4 0.6 4.0 3.3 1.0 2.3 0.7 0.6 1.6 8.8 0.6 3.5 0.5 2.0 0.6 5.3 1.6 0.6 0.6 1.2 1.6 0.6 1.6 0.6 0.6 1.2 0.6 1.2 1.0 1.7 0.0 0.6 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 10.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 5.7 11.7 30.3 13.6 4.0 3.3 1.6 8.8 5.3 1.7 PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40238759-40277487 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 22.2" "Cell line enhanced" "Detected in many" "CACO-2: 14.5;HaCaT: 22.5;hTCEpi: 13.8;SK-BR-3: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA031124 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: AB_10601044" "unprognostic (1.85e-3)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (7.79e-3)" "unprognostic (7.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (1.34e-2)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (8.87e-3)" "unprognostic (1.72e-1)" "unprognostic (1.79e-1)" "unprognostic (7.37e-3)" "unprognostic (3.34e-2)" 0.3 5.3 14.7 0.8 18.4 0.8 2.3 11.3 20.1 3.0 1.3 1.6 2.5 1.4 1.0 1.1 15.8 4.3 1.4 7.9 11.6 5.2 3.4 0.4 2.6 1.0 3.0 10.9 0.6 7.4 12.9 6.4 8.1 2.1 3.6 1.2 0.3 3.4 7.5 3.5 22.2 1.4 0.8 1.2 1.0 3.6 12.8 2.2 0.0 7.4 8.5 5.1 3.0 5.1 1.4 0.7 2.9 0.7 2.0 5.5 1.2 2.6 0.0 0.2 0.1 0.0 0.0 4.3 0.0 0.1 0.6 0.4 14.5 2.0 0.1 2.3 0.0 22.5 3.2 4.8 0.2 0.1 0.7 0.0 1.9 0.1 0.0 0.1 0.3 0.0 13.8 0.2 3.2 0.0 1.1 0.2 0.0 3.1 0.0 0.3 0.4 2.0 0.2 0.1 1.8 1.1 5.9 5.2 1.3 1.8 7.6 0.2 0.8 7.0 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.5 0.3 0.1 2.1 0.7 2.9 5.5 0.3 2.1 1.4 0.5 4.2 0.7 0.5 0.3 1.2 1.3 2.0 0.2 0.5 0.1 1.2 14.7 18.4 11.3 20.1 11.6 5.2 3.0 10.9 2.1 2.2 PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103031105 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 304.2" "Cell line enhanced" "Detected in many" "ASC diff: 76.6;fHDF/TERT166: 98.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" 59000000 "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: " "unprognostic (4.30e-3)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "prognostic favourable (1.63e-4)" "unprognostic (4.23e-2)" "unprognostic (6.30e-2)" "prognostic unfavourable (6.20e-4)" "unprognostic (7.58e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (9.91e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (9.79e-2)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" 16.5 24.5 8.2 6.5 16.4 0.8 17.3 6.6 16.5 74.9 14.0 5.4 9.5 5.8 21.3 83.8 11.7 10.6 11.5 304.2 8.8 23.5 13.7 2.1 13.2 5.8 10.0 7.6 17.0 16.4 49.5 18.3 26.3 15.5 13.4 9.5 8.7 53.8 29.4 22.0 8.5 8.5 18.5 4.8 8.9 17.2 7.2 4.6 1.8 21.7 13.2 7.3 15.8 15.3 0.5 2.0 10.1 5.3 16.2 14.1 6.3 14.9 2.2 27.6 12.2 76.6 45.9 11.0 42.6 63.8 12.6 38.5 7.3 19.9 0.0 9.2 98.2 5.1 1.5 18.7 34.9 1.8 6.2 3.1 9.0 2.3 11.6 0.9 3.4 25.1 8.1 9.2 7.0 26.0 0.1 2.1 35.7 3.0 0.0 0.4 4.9 8.3 1.1 15.4 8.3 48.7 1.7 13.1 9.0 18.1 1.1 11.1 4.7 1.0 20.0 40.1 10.4 18.8 12.6 4.7 1.1 0.0 46.0 4.2 34.5 1.9 5.3 0.1 14.1 0.9 10.0 0.5 8.5 10.4 2.0 0.3 2.9 4.8 10.1 16.2 1.9 1.1 12.1 6.3 8.2 16.4 6.6 16.5 8.8 23.5 10.0 7.6 15.5 4.6 PAN3 ENSG00000152520 "PAN3 poly(A) specific ribonuclease subunit" Q58A45 13 28138506-28295335 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028817 Approved "HPA028817: AB_10602016" "unprognostic (3.25e-2)" "unprognostic (2.10e-1)" "unprognostic (3.55e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (7.39e-2)" "unprognostic (8.17e-2)" "unprognostic (1.52e-1)" "unprognostic (4.26e-3)" "unprognostic (5.78e-2)" "unprognostic (6.56e-2)" "unprognostic (2.29e-2)" "unprognostic (4.22e-2)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (8.54e-2)" "unprognostic (2.42e-2)" 15.2 9.0 8.3 18.6 7.7 20.0 13.9 41.7 10.1 12.1 12.5 10.7 13.0 7.0 15.2 17.8 12.3 10.5 9.0 7.8 8.6 4.5 8.1 5.9 14.4 14.3 10.3 6.8 12.8 10.4 9.2 10.1 11.4 8.5 10.3 9.5 11.0 15.9 12.3 9.6 16.0 12.6 10.2 6.2 16.0 10.5 12.4 10.7 25.2 13.3 7.9 14.8 17.5 12.4 12.3 14.8 21.6 12.5 11.5 12.3 8.7 5.7 3.8 9.4 9.6 4.7 6.5 7.7 5.9 9.2 6.2 6.0 5.9 11.6 20.0 4.6 8.5 8.4 8.8 6.1 10.4 12.9 4.4 16.2 4.6 4.8 6.4 12.3 9.8 6.9 6.5 4.9 10.5 8.2 8.6 6.0 6.1 6.8 13.4 26.1 10.0 3.8 31.8 10.8 7.0 8.9 7.4 9.3 7.5 7.0 9.6 7.8 5.2 21.8 8.2 5.9 5.4 5.8 5.5 4.7 3.7 20.6 3.8 8.7 7.4 18.8 10.1 12.2 9.5 9.2 9.9 12.3 10.7 9.5 9.4 11.8 12.3 11.7 21.6 11.5 12.5 14.8 8.0 8.7 8.3 7.7 41.7 10.1 8.6 4.5 10.3 6.8 8.5 10.7 PANK2 "C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN" ENSG00000125779 "Pantothenate kinase 2" Q9BZ23 20 3888839-3929882 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008440 Approved Supported Cytosol Cytosol "HPA008440: AB_1079559" "unprognostic (4.50e-2)" "unprognostic (7.96e-3)" "unprognostic (2.26e-1)" "unprognostic (1.39e-2)" "unprognostic (1.68e-1)" "unprognostic (6.00e-2)" "prognostic unfavourable (1.20e-5)" "unprognostic (2.75e-1)" "unprognostic (3.39e-1)" "unprognostic (2.52e-1)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" "unprognostic (6.01e-3)" "unprognostic (1.73e-2)" "unprognostic (2.18e-3)" "unprognostic (2.63e-1)" "unprognostic (1.81e-1)" 15.2 21.5 18.7 18.5 18.9 20.8 19.7 21.8 24.8 14.7 14.4 16.8 10.7 11.8 15.5 15.5 28.9 19.1 14.3 11.0 17.4 18.6 18.8 20.3 16.1 18.5 16.2 16.2 14.4 13.5 15.3 15.7 18.1 20.8 14.5 16.4 17.0 15.8 13.2 14.4 12.8 14.5 16.6 12.3 20.6 12.1 28.9 14.1 23.2 17.0 10.5 24.6 17.3 16.4 5.8 8.6 8.0 12.8 8.3 6.4 3.1 21.4 13.9 15.0 7.6 18.0 15.6 8.2 14.1 15.5 18.6 24.1 18.7 11.5 17.4 6.5 15.8 17.7 16.1 27.4 23.8 5.1 7.1 23.8 9.9 34.9 15.1 15.8 7.9 13.7 12.0 20.7 13.4 17.4 17.5 16.3 20.0 5.3 13.6 14.0 15.0 10.4 11.2 20.9 11.0 11.5 19.7 19.6 9.6 17.5 19.2 34.9 11.6 12.8 11.9 22.3 11.2 29.1 21.6 9.2 26.6 13.3 6.6 14.5 17.4 1.6 11.2 4.7 4.4 12.8 4.3 4.7 4.3 4.5 8.6 5.8 4.4 4.0 8.0 8.3 10.7 3.0 6.4 3.1 18.7 18.9 21.8 24.8 17.4 18.6 16.2 16.2 20.8 14.1 PANK3 FLJ12899 ENSG00000120137 "Pantothenate kinase 3" Q9H999 5 168548495-168579600 "Enzymes, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 63.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062358 Approved "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA062358: " "unprognostic (1.24e-2)" "unprognostic (5.71e-2)" "prognostic favourable (3.94e-4)" "unprognostic (7.65e-3)" "unprognostic (2.47e-2)" "unprognostic (2.42e-2)" "unprognostic (1.20e-2)" "unprognostic (8.43e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-1)" "unprognostic (9.48e-2)" "unprognostic (2.30e-1)" "unprognostic (3.71e-2)" "unprognostic (1.05e-1)" "unprognostic (1.43e-1)" "unprognostic (1.97e-3)" "unprognostic (2.01e-1)" 9.1 16.6 11.6 17.5 10.4 10.5 17.6 22.8 11.9 8.9 23.9 9.0 8.5 28.0 10.2 8.8 12.8 7.8 6.9 7.4 11.7 9.1 13.2 39.2 12.5 8.2 8.4 7.5 10.7 8.8 14.6 11.2 9.4 10.8 9.1 17.9 6.7 11.0 9.6 8.2 11.9 63.0 8.0 10.3 9.6 10.9 10.2 11.0 10.2 10.5 13.4 8.2 9.9 11.6 4.1 2.7 3.5 4.7 0.9 2.5 1.1 13.8 7.8 32.3 17.2 12.1 14.1 13.7 8.3 8.9 11.2 16.5 12.9 12.9 21.3 13.7 11.7 10.0 21.6 16.7 20.1 19.8 10.5 10.9 7.4 9.5 14.1 14.7 14.8 11.2 22.6 14.0 15.8 13.1 10.0 21.6 15.2 7.7 14.6 6.7 13.8 5.7 10.7 22.1 8.7 14.0 20.5 15.1 32.3 9.6 15.8 23.6 20.6 18.6 13.4 15.1 21.2 8.9 17.7 15.1 20.7 15.9 8.9 15.0 11.7 3.5 3.2 1.6 1.9 3.8 2.5 4.1 1.9 1.9 2.0 1.6 1.3 2.3 1.3 0.9 4.7 2.7 2.4 1.1 11.6 10.4 22.8 11.8 11.7 9.1 8.4 7.5 10.8 11.0 PANK4 FLJ10782 ENSG00000157881 "Pantothenate kinase 4" Q9NVE7 1 2508533-2526628 "Enzymes, Predicted intracellular proteins" "Coenzyme A biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 43.1" "Cell line enhanced" "Detected in many" "BJ: 8.9;HDLM-2: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011723, HPA012036, HPA027961" Uncertain Approved Cytosol Cytosol "HPA011723: , HPA012036: AB_1854952, HPA027961: AB_10602042" "unprognostic (1.23e-1)" "unprognostic (2.31e-1)" "unprognostic (3.36e-1)" "unprognostic (1.13e-1)" "unprognostic (4.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-1)" "unprognostic (6.51e-2)" "unprognostic (1.80e-1)" "unprognostic (1.18e-2)" "unprognostic (3.29e-2)" "prognostic favourable (1.57e-5)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (2.25e-1)" "unprognostic (8.15e-2)" 5.3 14.4 10.7 17.8 12.6 4.2 5.4 14.9 12.4 5.5 7.1 6.8 4.9 4.2 7.0 4.2 9.8 5.6 9.2 11.8 8.0 5.2 7.2 7.0 6.7 12.5 9.0 6.8 5.7 5.8 4.2 8.3 6.7 7.4 5.8 6.1 8.9 5.6 5.3 43.1 19.0 7.6 9.1 4.4 8.1 6.3 11.0 9.7 9.4 6.8 6.8 7.2 7.2 5.7 4.5 4.8 11.7 6.9 11.4 8.9 5.3 2.4 6.6 2.3 0.0 0.0 2.7 1.5 8.9 0.0 8.0 7.6 0.0 0.0 1.1 3.0 2.4 3.8 1.9 0.0 1.7 9.2 5.6 0.0 3.8 5.5 2.5 0.0 4.6 0.0 0.0 0.0 0.0 1.9 2.5 0.0 2.1 0.0 1.3 0.2 0.0 2.8 0.0 0.0 1.8 0.0 0.0 2.0 0.0 5.0 1.8 0.0 0.0 3.3 0.0 0.0 1.9 4.6 2.1 1.3 4.5 5.9 3.0 0.9 0.0 11.7 4.9 4.5 6.2 6.6 5.1 4.5 3.9 6.4 4.8 3.0 7.4 8.0 6.4 11.4 6.9 0.9 8.9 5.3 10.7 12.6 14.9 12.4 8.0 5.2 9.0 6.8 7.4 9.7 PAOX PAO ENSG00000148832 "Polyamine oxidase" Q6QHF9 10 133379234-133391694 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 36.7" "Cell line enhanced" "Detected in many" "A-431: 6.2;U-266/70: 18.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive B-cell: 4.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047782 Uncertain Nucleoplasm,Centrosome "Nucleoplasm, Centrosome" "HPA047782: " "unprognostic (3.67e-3)" "prognostic favourable (6.07e-5)" "unprognostic (2.49e-2)" "unprognostic (1.28e-3)" "unprognostic (1.96e-2)" "prognostic favourable (1.38e-5)" "unprognostic (7.39e-2)" "unprognostic (1.99e-3)" "unprognostic (2.20e-1)" "unprognostic (4.48e-2)" "unprognostic (1.11e-2)" "unprognostic (2.99e-1)" "prognostic favourable (9.49e-4)" "unprognostic (3.56e-2)" "unprognostic (2.86e-1)" "unprognostic (7.61e-2)" "unprognostic (8.29e-3)" 6.7 4.1 4.3 5.8 6.7 1.5 4.7 6.8 8.7 3.7 6.0 10.8 5.6 5.6 3.7 1.8 7.4 3.4 2.4 2.5 5.7 2.7 8.9 9.2 2.8 5.2 10.0 3.4 3.6 3.2 1.9 2.5 2.1 4.2 4.8 1.5 2.8 9.9 5.1 3.5 4.4 8.5 2.8 4.7 8.2 7.5 36.7 7.6 0.7 2.4 2.1 5.4 4.6 4.2 4.3 1.1 1.0 1.0 1.7 0.3 0.4 6.2 0.0 0.2 1.2 0.0 0.7 1.6 2.8 1.2 1.4 0.2 1.1 0.1 0.0 0.9 0.6 3.5 0.4 0.8 0.6 4.1 0.5 0.5 0.0 0.2 1.7 0.0 1.0 0.1 0.3 0.9 0.4 0.1 4.9 0.3 0.0 0.1 0.0 0.1 1.2 3.0 4.6 0.0 0.0 0.1 0.0 0.3 2.2 0.9 0.1 0.0 1.3 0.0 2.7 0.3 1.4 1.2 0.0 18.1 3.3 1.7 0.0 0.0 0.1 1.0 0.3 0.0 0.2 1.0 0.0 1.6 0.3 0.2 1.1 4.3 0.0 0.0 0.0 1.7 0.9 0.8 0.0 0.4 4.3 6.7 6.8 6.5 5.7 2.7 10.0 3.4 4.2 7.6 PAPD4 "FLJ38499, GLD2, TUT2" ENSG00000164329 "Poly(A) RNA polymerase D4, non-canonical" Q6PIY7 5 79612120-79686648 "Enzymes, Predicted intracellular proteins" "mRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054468 Approved Cytosol Cytosol "HPA054468: " "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.25e-3)" "unprognostic (1.91e-1)" "unprognostic (8.03e-2)" "unprognostic (2.80e-3)" "unprognostic (2.10e-2)" "unprognostic (1.10e-1)" "unprognostic (6.80e-2)" "unprognostic (1.57e-3)" "unprognostic (9.37e-2)" "unprognostic (2.21e-1)" "unprognostic (7.71e-2)" "unprognostic (2.38e-1)" "unprognostic (8.43e-3)" "unprognostic (5.84e-3)" "unprognostic (2.67e-3)" 25.4 21.1 15.8 34.4 22.1 42.1 27.9 20.9 30.3 23.8 22.6 24.7 22.7 19.2 34.4 28.1 22.0 20.7 23.3 16.5 16.5 14.6 20.0 25.3 25.6 34.7 19.4 20.2 29.6 21.4 18.0 23.1 25.7 17.2 20.6 23.3 23.8 21.4 28.3 21.0 25.5 25.4 23.1 22.2 37.4 21.0 26.0 21.2 33.8 24.9 21.3 29.3 22.6 21.9 20.2 19.5 22.3 22.1 19.3 29.9 15.7 11.4 8.0 8.9 14.1 15.7 18.3 14.3 13.9 21.4 16.3 26.1 7.1 13.7 21.5 7.3 15.3 11.0 11.4 15.4 18.7 15.9 10.5 12.2 9.9 11.0 20.4 18.0 16.9 16.1 16.8 11.5 21.6 13.7 13.9 15.9 17.9 6.2 20.5 23.2 8.3 5.7 18.4 9.0 23.9 15.8 16.5 5.9 10.8 11.0 12.1 21.8 10.4 28.6 12.6 8.8 6.0 8.5 15.3 16.7 13.9 21.3 15.6 19.0 12.3 22.3 19.1 18.6 18.2 22.1 29.9 20.2 19.9 19.9 19.5 16.2 19.3 19.8 17.3 19.3 21.7 10.7 20.2 15.7 15.8 22.1 20.9 30.3 16.5 14.6 19.4 20.2 17.2 21.2 PAPD5 TRF4-2 ENSG00000121274 "Poly(A) RNA polymerase D5, non-canonical" Q8NDF8 16 50152918-50235310 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, rRNA processing" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042968, HPA048225" Uncertain "HPA042968: , HPA048225: " "unprognostic (1.05e-2)" "unprognostic (4.09e-2)" "unprognostic (1.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.27e-1)" "unprognostic (2.91e-2)" "unprognostic (4.33e-2)" "unprognostic (2.46e-1)" "unprognostic (7.83e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (3.30e-2)" "prognostic favourable (1.85e-4)" "unprognostic (4.24e-2)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (7.00e-2)" 9.4 9.9 5.9 8.8 8.6 19.2 12.6 14.9 10.8 15.9 10.0 4.5 8.8 11.1 13.1 6.3 7.4 10.8 6.3 8.0 7.7 6.9 10.0 11.9 8.5 11.2 6.4 8.0 10.5 7.9 18.5 13.4 9.2 7.5 10.0 6.4 6.7 7.6 9.8 9.9 8.1 9.4 9.7 6.1 6.0 8.0 12.3 8.0 6.8 7.5 6.0 6.6 13.1 30.8 3.5 4.9 4.6 2.9 7.2 5.6 1.2 11.3 8.7 7.1 12.7 11.2 9.5 9.1 10.2 10.4 12.3 5.7 12.0 8.1 13.7 12.2 12.4 8.6 13.3 7.6 16.2 8.0 8.7 8.2 4.7 15.5 12.6 6.8 12.7 5.7 9.4 10.1 12.8 8.5 8.4 4.8 11.3 4.9 9.5 10.2 9.2 9.4 12.8 14.2 17.9 3.5 4.2 9.1 5.4 10.3 13.3 7.0 4.4 5.0 7.3 11.4 10.0 9.9 5.8 9.6 7.4 18.1 6.8 6.3 8.1 4.6 2.6 1.3 4.0 2.9 3.5 2.9 4.3 4.8 2.0 3.5 4.8 5.6 4.0 7.2 2.1 4.9 3.7 1.2 5.9 8.6 14.9 10.8 7.7 6.9 6.4 8.0 7.5 8.0 PAPD7 "LAK-1, POLK, POLS, TRF4, TRF4-1" ENSG00000112941 "Poly(A) RNA polymerase D7, non-canonical" Q5XG87 5 6713007-6757048 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045487, HPA046742" Enhanced Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus" Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA045487: AB_2679346, HPA046742: AB_2679781" "unprognostic (1.45e-1)" "unprognostic (2.96e-1)" "unprognostic (2.08e-2)" "unprognostic (2.12e-3)" "unprognostic (7.57e-2)" "unprognostic (1.30e-2)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.62e-1)" "unprognostic (9.78e-2)" "unprognostic (3.10e-3)" "unprognostic (3.73e-2)" "prognostic unfavourable (7.99e-5)" "unprognostic (6.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.60e-2)" "prognostic favourable (8.55e-4)" 13.5 7.9 9.6 13.9 11.1 25.8 16.3 22.7 12.3 15.1 16.6 10.6 14.8 9.5 13.2 8.0 12.2 11.3 11.4 8.6 10.7 7.3 9.7 19.9 13.2 14.1 14.8 5.8 18.5 13.3 13.2 12.2 10.0 9.0 11.6 8.3 10.2 17.0 10.6 10.4 16.7 13.1 13.9 7.9 14.8 10.1 11.1 11.7 25.4 11.3 11.3 11.6 12.5 34.9 1.9 3.8 0.7 0.7 0.5 2.3 0.8 16.3 11.1 13.7 16.8 9.9 8.9 19.7 11.1 14.0 13.9 15.8 11.5 9.1 12.0 8.6 13.7 12.2 11.1 8.6 12.8 13.4 7.1 6.1 35.1 6.2 6.2 9.2 9.3 6.0 7.5 15.5 10.0 8.1 8.2 15.9 11.3 9.0 12.5 12.0 7.4 8.7 11.3 11.6 3.0 5.5 9.4 13.6 10.4 26.6 12.9 7.6 7.8 5.1 7.1 16.7 17.5 14.6 15.5 15.2 6.3 10.6 10.8 8.6 10.3 0.0 0.7 0.7 2.1 0.4 2.3 1.9 1.7 1.6 1.2 1.5 1.9 1.7 0.4 0.5 0.6 3.8 1.8 0.8 9.6 11.1 22.7 12.3 10.7 7.3 14.8 5.8 9.0 11.7 PAPOLA PAP ENSG00000090060 "Poly(A) polymerase alpha" P51003 14 96501433-96567111 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001788 Supported Supported Nucleoplasm Nucleoplasm "HPA001788: AB_1079564" "unprognostic (3.18e-1)" "unprognostic (1.30e-1)" "unprognostic (9.69e-2)" "unprognostic (7.26e-2)" "unprognostic (9.10e-2)" "unprognostic (5.10e-3)" "prognostic unfavourable (2.41e-5)" "unprognostic (2.12e-2)" "unprognostic (2.82e-2)" "unprognostic (1.38e-3)" "unprognostic (3.13e-1)" "unprognostic (1.22e-3)" "unprognostic (3.37e-1)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (1.08e-2)" "unprognostic (4.05e-1)" 35.8 43.4 49.1 45.7 51.6 54.5 39.7 61.2 60.5 41.0 45.1 25.2 45.6 34.9 43.8 48.3 42.0 38.7 35.6 71.8 46.3 39.6 40.0 50.2 37.1 44.7 48.1 39.7 58.2 52.9 50.2 68.7 54.5 45.6 45.1 45.8 24.0 39.2 45.5 46.4 35.5 45.5 38.9 41.9 50.9 40.4 53.0 55.7 53.0 54.8 34.8 49.6 44.9 119.5 26.4 23.0 39.0 23.5 25.2 23.4 19.8 32.0 31.0 39.9 40.0 28.9 32.7 90.8 29.4 31.8 35.0 33.7 35.8 33.2 43.5 33.9 34.4 27.8 13.0 40.5 62.8 35.9 21.1 35.1 23.5 35.1 29.9 45.9 35.6 29.8 35.5 39.1 35.0 39.1 32.9 39.9 33.7 46.7 35.9 23.3 27.2 35.3 38.4 48.6 25.2 34.9 51.2 41.0 27.2 39.2 30.8 28.6 43.7 40.4 31.1 24.7 19.7 27.8 35.8 31.5 47.1 38.4 40.0 35.2 41.4 39.0 19.7 32.7 15.5 23.5 20.4 23.8 19.6 22.6 23.0 26.4 23.4 21.8 27.4 25.2 22.6 15.2 18.7 19.8 49.1 51.6 61.2 60.5 46.3 39.6 48.1 39.7 45.6 55.7 PAPOLG FLJ12972 ENSG00000115421 "Poly(A) polymerase gamma" Q9BWT3 2 60756230-60802085 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017795, HPA035349, HPA035350" Approved Enhanced Nucleoplasm Nucleoplasm "CAB017795: , HPA035349: , HPA035350: " "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (3.39e-2)" "unprognostic (5.56e-2)" "unprognostic (3.54e-1)" "unprognostic (6.72e-4)" "unprognostic (2.49e-1)" "unprognostic (6.97e-3)" "unprognostic (6.83e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-1)" "prognostic unfavourable (4.21e-4)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (2.62e-2)" 12.3 9.5 11.6 11.6 11.9 5.8 9.9 19.4 15.3 10.2 8.2 9.8 7.8 6.8 12.1 6.2 10.1 9.0 10.2 8.5 15.1 10.1 8.6 6.9 9.4 14.8 10.9 11.3 17.1 9.9 13.3 18.9 11.8 12.5 9.6 9.2 7.7 11.1 8.7 13.1 11.7 9.7 9.9 21.0 15.0 9.1 14.2 11.0 23.1 27.5 6.6 14.3 10.9 11.1 6.1 3.7 13.2 6.9 9.4 9.7 4.1 5.1 4.8 9.0 7.3 11.6 8.7 8.6 5.7 5.6 4.9 5.2 8.1 4.4 7.4 6.0 4.4 8.7 12.7 5.4 9.2 12.8 6.8 9.4 4.7 5.7 7.0 9.8 6.5 6.5 6.4 5.9 12.4 7.8 9.2 7.0 5.4 4.1 11.3 6.7 14.3 4.4 9.3 16.0 6.6 5.3 4.9 5.3 7.4 9.1 5.7 5.1 3.8 6.0 7.3 6.3 7.6 4.7 5.3 7.0 4.1 18.0 5.1 11.2 4.5 13.2 4.1 8.7 6.7 4.3 8.3 5.9 7.2 6.0 3.7 6.1 7.9 7.3 10.6 9.4 6.9 3.3 9.7 4.1 11.6 11.9 19.4 15.3 15.1 10.1 10.9 11.3 12.5 11.0 PAPPA "ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1" ENSG00000182752 "Pappalysin 1" Q13219 9 116153804-116402322 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 86 "placenta: 484.6" "Cell line enhanced" "Detected in some" "ASC diff: 19.0;ASC TERT1: 14.5;HSkMC: 52.2;U-138 MG: 13.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "midbrain: 10.4;olfactory region: 4.1;pons and medulla: 8.3;thalamus: 4.8" "HPA001667, CAB016724" Enhanced "Secreted in female reproductive system" 41000 "CAB016724: , HPA001667: AB_1854960" "unprognostic (3.25e-1)" "unprognostic (6.18e-6)" "unprognostic (2.47e-1)" "unprognostic (6.49e-2)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (5.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.87e-2)" "unprognostic (6.87e-3)" "unprognostic (8.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.37e-3)" "unprognostic (2.48e-1)" "unprognostic (4.01e-1)" "unprognostic (1.02e-3)" 4.8 2.3 0.5 1.0 0.5 0.0 0.8 0.4 0.6 3.6 2.4 0.6 1.0 0.1 3.5 1.0 3.6 2.0 1.1 3.7 0.4 0.0 4.3 0.5 2.4 0.7 0.4 0.4 1.4 0.7 5.6 0.7 484.6 0.7 1.4 0.9 0.9 0.5 1.2 0.5 1.1 0.9 2.4 0.6 0.6 1.0 0.8 0.5 0.4 1.3 1.0 1.0 2.3 3.4 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 5.4 8.3 0.0 19.0 14.5 0.0 4.4 7.8 1.2 2.1 0.0 0.0 0.0 0.0 3.1 0.6 0.0 0.0 5.9 0.0 0.0 0.9 4.5 0.0 9.2 0.0 0.0 52.2 0.0 6.1 0.7 0.0 0.2 0.0 1.4 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 10.5 13.6 0.7 0.3 0.5 0.0 0.0 0.0 9.7 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.4 0.6 0.4 0.0 0.4 0.4 0.7 0.5 PAPPA2 "PAPP-A2, PAPPE, PLAC3" ENSG00000116183 "Pappalysin 2" Q9BXP8 1 176463171-176845605 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "placenta: 406.4" "Cell line enriched" "Detected in some" 5 "U-87 MG: 20.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018412, HPA018430" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted in female reproductive system" "Endoplasmic reticulum, Vesicles" "HPA018412: AB_1854962, HPA018430: AB_1854961" "unprognostic (2.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-2)" "unprognostic (9.04e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (3.54e-2)" "unprognostic (1.29e-2)" "unprognostic (4.39e-2)" "unprognostic (2.85e-2)" "unprognostic (1.52e-4)" "unprognostic (1.85e-1)" "unprognostic (8.18e-4)" "unprognostic (4.35e-2)" 0.6 0.0 0.6 0.2 0.2 0.0 3.0 0.8 0.3 5.0 0.6 0.2 0.2 0.0 0.3 0.2 0.2 0.2 1.1 0.2 0.2 0.1 11.6 0.7 0.2 0.2 0.2 0.2 0.2 1.5 0.0 1.2 406.4 0.3 0.2 0.2 0.2 0.2 0.3 0.2 0.0 0.2 0.3 0.5 0.2 1.0 0.3 0.2 0.2 0.5 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.2 4.5 2.2 3.7 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.8 0.5 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.3 1.7 1.4 0.1 0.6 0.3 0.4 0.0 20.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.8 0.3 0.2 0.1 0.2 0.2 0.3 0.2 PAPSS1 "ATPSK1, PAPSS" ENSG00000138801 "3'-phosphoadenosine 5'-phosphosulfate synthase 1" O43252 4 107590276-107720452 "Enzymes, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 50.3;eosinophil: 62.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 62.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049781 Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA049781: " "unprognostic (1.36e-2)" "unprognostic (5.03e-2)" "prognostic favourable (9.14e-4)" "prognostic favourable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "prognostic unfavourable (2.70e-5)" "unprognostic (1.58e-2)" "unprognostic (1.05e-1)" "unprognostic (8.92e-2)" "unprognostic (1.42e-1)" "unprognostic (5.76e-2)" "unprognostic (6.23e-3)" "unprognostic (1.29e-1)" "unprognostic (1.72e-1)" "unprognostic (1.61e-2)" "unprognostic (1.38e-1)" 13.5 7.4 24.3 14.4 28.5 11.1 25.2 16.4 32.2 26.6 10.0 45.0 9.4 7.9 25.1 22.8 18.3 24.9 13.3 7.7 31.3 23.9 16.7 5.1 22.0 14.7 29.7 21.9 15.6 24.6 15.6 15.5 8.5 38.2 21.7 12.7 9.5 32.2 14.0 3.3 24.5 8.5 17.0 59.9 9.6 30.4 8.1 25.5 14.7 10.3 11.0 24.6 16.5 13.7 8.5 9.2 62.2 10.2 4.6 6.8 5.8 10.5 9.6 16.3 20.4 20.2 25.5 13.1 13.4 25.4 13.2 17.7 14.7 15.3 16.5 8.6 24.7 13.3 15.4 26.6 17.0 38.7 11.7 19.2 20.9 32.9 11.1 29.1 33.3 21.1 13.8 15.2 12.5 29.2 4.2 32.1 36.9 16.1 23.4 9.0 17.5 10.7 19.7 25.9 4.7 19.8 14.7 18.6 26.9 13.9 21.1 16.4 12.5 4.5 17.2 16.5 17.0 11.0 11.3 25.8 17.1 15.4 20.1 22.3 25.9 50.3 8.9 62.2 3.0 9.6 3.5 8.5 4.0 3.4 9.2 4.1 2.5 2.9 9.4 4.6 10.2 1.8 6.8 5.8 24.3 28.5 16.4 32.2 31.3 23.9 29.7 21.9 38.2 25.5 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.2;liver: 49.0" "Cell line enhanced" "Detected in many" "BJ: 34.9;fHDF/TERT166: 88.3;HHSteC: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 5.3;myeloid DC: 2.7;non-classical monocyte: 9.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.7;monocytes: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria Mitochondria "HPA071224: , HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavourable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favourable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavourable (3.21e-5)" "unprognostic (3.46e-3)" 16.0 59.2 3.5 18.1 6.0 0.3 18.1 1.9 4.3 8.6 25.5 2.2 1.9 9.2 4.0 7.0 3.7 5.3 10.7 9.1 3.9 2.1 9.9 49.0 31.3 15.6 4.4 1.6 10.8 21.2 0.4 1.7 19.0 5.2 3.8 21.2 6.2 6.2 2.0 4.8 1.7 19.4 5.5 3.4 2.9 2.9 3.6 4.3 0.8 7.3 6.2 11.0 5.7 5.3 0.0 2.7 0.8 9.7 0.0 0.1 0.8 3.5 3.6 1.1 0.0 25.3 32.3 0.0 34.9 29.9 21.2 15.4 0.1 0.7 0.0 1.8 88.3 1.5 2.6 2.4 24.3 0.0 1.9 1.6 2.6 0.0 38.3 0.0 0.7 11.4 0.0 12.2 1.0 17.7 0.0 16.5 14.9 13.3 0.0 0.1 1.3 4.5 0.0 0.0 0.0 22.1 1.5 0.1 0.3 17.0 0.6 0.2 2.5 0.9 22.0 7.2 4.2 24.4 2.5 0.0 0.1 0.0 3.4 0.0 0.0 0.0 1.4 0.0 0.0 5.3 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.8 0.0 9.7 0.0 0.0 0.8 3.5 6.0 1.9 4.3 3.9 2.1 4.4 1.6 5.2 4.3 PARG ENSG00000227345 "Poly(ADP-ribose) glycohydrolase" Q86W56 10 49818279-49970203 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021819, HPA053007" Enhanced Supported Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "HPA021819: AB_1854974, HPA053007: " "unprognostic (5.77e-3)" "unprognostic (6.74e-2)" "unprognostic (3.06e-2)" "unprognostic (9.90e-2)" "unprognostic (1.22e-2)" "unprognostic (1.33e-1)" "prognostic unfavourable (5.57e-5)" "unprognostic (1.21e-1)" "unprognostic (3.97e-1)" "unprognostic (8.34e-2)" "unprognostic (1.47e-1)" "unprognostic (4.06e-2)" "unprognostic (5.20e-3)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (8.54e-2)" "unprognostic (1.13e-1)" 4.0 5.6 4.3 4.2 5.4 1.4 5.3 7.8 6.3 4.8 5.1 6.7 4.9 3.0 6.2 4.3 3.6 6.6 4.6 5.9 9.2 5.2 3.5 5.8 4.5 4.7 3.5 8.1 4.7 5.8 4.9 6.1 4.7 5.1 8.1 6.7 5.1 4.7 4.0 5.9 4.7 5.8 4.9 6.9 4.4 4.8 6.9 7.0 12.5 7.7 8.3 9.4 5.5 12.7 10.6 18.7 13.7 9.0 11.2 13.7 12.7 14.0 14.8 14.2 8.5 11.9 9.6 8.3 10.8 14.5 15.7 8.0 16.0 14.7 14.6 9.8 8.7 9.3 10.2 14.1 8.2 7.2 15.5 12.4 20.5 9.0 16.6 8.5 11.1 7.1 15.6 12.7 18.4 24.3 18.6 21.2 11.1 12.0 8.2 12.9 16.3 10.3 16.4 13.3 18.9 7.9 9.1 9.3 11.3 9.6 14.2 9.4 14.1 20.5 15.9 15.0 6.7 12.5 6.2 3.0 5.2 5.5 7.9 6.9 7.1 6.7 7.0 6.9 9.4 9.1 3.0 8.3 7.7 5.4 5.5 5.5 PARK7 "DJ-1, DJ1, GATD2" ENSG00000116288 "Parkinsonism associated deglycase" Q99497 1 7954291-7985505 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Fertilization, Inflammatory response, Stress response" "Chaperone, Hydrolase, Protease, RNA-binding" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004190, CAB005870" Supported Supported Nucleoplasm,Cytosol 69000000 "Nucleoplasm, Cytosol" "CAB005870: AB_444361, HPA004190: AB_1079566" "unprognostic (6.88e-3)" "unprognostic (7.50e-2)" "unprognostic (3.48e-2)" "unprognostic (1.16e-2)" "unprognostic (4.08e-2)" "unprognostic (5.68e-2)" "unprognostic (7.45e-2)" "unprognostic (9.63e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-3)" "unprognostic (8.17e-2)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (7.43e-2)" 44.6 67.9 69.3 38.1 64.9 33.7 45.4 57.2 62.7 34.0 36.4 33.4 43.2 27.3 35.8 56.6 40.9 39.0 41.6 71.7 56.9 57.2 60.5 77.1 28.6 46.1 61.6 57.2 45.9 60.4 66.6 48.4 44.6 41.2 44.7 39.5 38.6 46.5 39.4 128.7 19.8 27.5 48.1 52.5 37.5 37.2 38.2 32.2 38.8 71.6 43.3 46.5 41.3 43.4 49.5 141.8 38.8 61.0 52.8 87.2 90.6 68.2 61.5 61.3 70.4 66.0 63.5 30.1 63.6 59.6 62.6 50.6 56.0 74.8 84.7 71.9 68.2 49.0 66.1 85.0 81.4 75.3 71.4 91.0 91.9 83.1 57.0 86.8 56.1 59.8 36.3 63.8 76.7 65.6 88.3 63.1 86.8 63.9 60.4 110.3 50.0 63.5 46.5 82.3 116.1 98.2 35.1 71.7 60.2 63.6 98.3 99.2 54.8 64.7 62.1 57.8 46.1 53.3 69.7 61.3 98.3 120.5 76.2 132.9 81.8 22.7 61.0 38.8 52.6 55.4 49.7 49.5 52.7 62.2 73.9 38.6 45.6 52.4 21.0 52.8 44.1 141.8 87.2 90.6 69.3 64.9 57.2 62.7 56.9 57.2 61.6 57.2 41.2 32.2 PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA019545 Approved Approved Mitochondria Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favourable (9.11e-5)" 24.2 20.6 26.2 19.2 30.1 21.2 30.4 22.1 29.6 22.7 29.0 24.4 19.4 21.5 20.2 43.8 21.4 19.6 21.2 30.9 23.1 23.4 27.0 26.7 20.3 26.5 28.4 20.3 20.3 47.5 22.0 20.6 18.5 19.5 22.1 31.3 25.9 35.1 33.4 41.2 22.3 27.0 38.1 19.4 22.3 24.5 22.2 18.9 22.1 20.7 25.4 24.3 23.2 18.2 21.5 45.4 44.3 50.0 21.5 25.9 35.4 32.1 15.3 11.3 9.6 11.0 12.7 23.5 12.1 16.4 23.3 18.3 46.9 16.8 14.3 26.9 15.3 14.3 18.0 18.6 26.3 20.4 22.1 21.6 10.2 25.6 16.6 21.4 18.3 17.2 23.9 16.3 20.0 16.5 12.2 13.4 19.1 34.8 40.9 52.5 30.3 15.7 18.1 22.1 26.0 21.7 26.9 11.4 16.3 14.4 46.4 29.5 47.7 40.7 9.7 8.7 18.9 17.9 30.7 26.9 18.2 33.0 16.6 21.9 10.4 27.6 50.0 44.3 19.0 35.4 21.7 21.5 21.6 22.1 45.4 19.9 25.9 21.1 14.5 21.5 26.2 27.0 24.4 35.4 26.2 30.1 22.1 29.6 23.1 23.4 28.4 20.3 19.5 18.9 PARN DAN ENSG00000140694 "Poly(A)-specific ribonuclease" O95453 16 14435701-14632728 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease mutation, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006314, CAB011673, HPA012010" Supported Supported "Nuclear speckles" "Nuclear speckles" "CAB011673: AB_778216, HPA006314: AB_1079567, HPA012010: AB_1854976" "unprognostic (2.54e-1)" "unprognostic (3.43e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-1)" "unprognostic (2.28e-1)" "prognostic unfavourable (4.64e-4)" "unprognostic (2.99e-3)" "unprognostic (5.07e-2)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (2.16e-3)" "unprognostic (1.75e-1)" "unprognostic (1.52e-1)" "unprognostic (3.25e-2)" "unprognostic (2.46e-1)" "unprognostic (3.10e-3)" "unprognostic (1.09e-2)" 19.4 25.9 14.9 23.5 19.1 12.5 19.8 16.8 23.5 21.3 21.0 22.7 23.3 14.4 24.6 29.0 19.0 19.4 22.5 18.4 15.4 19.0 17.9 18.9 26.7 31.6 22.2 17.9 21.8 22.7 37.4 26.0 21.9 21.0 21.4 21.8 21.0 18.9 31.0 19.2 21.0 18.8 28.7 18.3 20.1 19.6 25.4 19.6 29.4 27.8 14.0 26.8 25.6 19.3 16.1 15.6 13.3 14.8 15.0 17.8 11.0 11.8 13.9 7.3 9.2 12.2 14.0 8.5 10.0 14.1 12.5 12.0 7.7 11.0 21.0 25.5 11.5 12.8 16.8 11.3 17.4 17.8 9.9 14.4 9.6 17.1 12.8 17.1 14.4 12.7 14.2 11.2 16.1 8.4 12.3 11.9 12.2 14.6 17.2 11.1 9.9 8.3 22.8 16.5 21.2 8.5 8.2 9.2 6.6 20.5 11.1 13.8 11.8 9.9 7.7 12.2 6.4 6.6 10.2 12.1 12.9 25.7 13.4 12.6 13.4 11.9 11.1 13.3 13.5 14.8 13.9 16.1 13.1 15.5 15.6 13.9 17.8 17.8 7.2 15.0 14.3 10.8 14.7 11.0 14.9 19.1 16.8 23.5 15.4 19.0 22.2 17.9 21.0 19.6 PARP1 "ADPRT, PARP, PPOL" ENSG00000143799 "Poly(ADP-ribose) polymerase 1" P09874 1 226360691-226408079 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "DNA-binding, Glycosyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727" Supported Supported Enhanced Nucleoplasm 39000 Nucleoplasm "CAB000147: AB_430876, CAB003839: AB_365493, CAB003840: AB_562187, CAB075726: , CAB075727: , HPA045168: " "unprognostic (2.02e-1)" "unprognostic (9.40e-2)" "unprognostic (7.44e-3)" "unprognostic (1.32e-1)" "unprognostic (4.29e-1)" "unprognostic (9.22e-2)" "prognostic unfavourable (3.40e-4)" "unprognostic (2.20e-1)" "unprognostic (3.62e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavourable (1.35e-5)" "unprognostic (2.38e-2)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (2.64e-1)" 17.3 16.6 31.2 35.7 31.2 14.3 15.3 21.1 29.2 14.3 21.8 37.4 10.3 15.0 18.2 13.0 18.1 15.0 10.8 24.2 27.8 21.9 13.4 24.8 14.1 56.3 40.7 21.8 14.6 28.1 62.6 22.9 28.7 30.4 22.0 19.2 16.3 17.0 24.7 47.3 11.7 19.6 25.5 49.1 32.7 15.9 22.5 34.8 29.5 14.5 16.5 70.2 19.9 13.7 53.0 16.5 9.0 17.5 11.1 21.8 11.5 28.5 15.3 42.6 30.1 11.2 9.2 24.3 18.9 16.9 25.8 21.2 24.3 14.0 83.2 28.3 11.5 21.5 58.5 18.6 22.7 34.9 81.7 32.2 20.4 15.9 6.7 53.4 15.6 9.1 7.4 20.7 14.7 20.0 51.2 42.5 13.3 13.6 17.1 19.3 78.4 30.4 51.8 73.0 76.9 12.1 20.4 42.9 37.6 24.6 27.6 15.5 23.2 33.5 15.2 13.7 22.7 18.5 35.4 17.3 29.0 71.5 11.4 18.1 30.7 9.0 6.7 6.9 18.3 11.3 21.6 46.8 19.4 18.0 14.3 53.0 15.2 16.4 1.0 11.1 17.5 16.5 21.8 11.5 31.2 31.2 21.1 28.4 27.8 21.9 40.7 21.8 30.4 34.8 PARP10 FLJ14464 ENSG00000178685 "Poly(ADP-ribose) polymerase family member 10" Q53GL7 8 143977153-144012772 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 16.4" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "HPA028122, HPA052427" Approved Supported "Nucleoli,Golgi apparatus,Cytosol" Nucleoli "Golgi apparatus, Cytosol" "HPA028122: AB_10601979, HPA052427: " "unprognostic (9.80e-3)" "unprognostic (5.89e-2)" "unprognostic (2.63e-3)" "unprognostic (9.10e-2)" "unprognostic (1.74e-2)" "unprognostic (1.46e-2)" "unprognostic (7.37e-2)" "unprognostic (3.61e-1)" "unprognostic (9.05e-2)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (1.05e-1)" "unprognostic (4.69e-3)" "unprognostic (1.09e-3)" "unprognostic (4.17e-2)" "unprognostic (8.69e-2)" "unprognostic (5.30e-3)" 14.2 18.8 8.8 27.4 9.5 15.7 18.6 5.3 8.7 14.4 16.5 9.3 20.7 20.5 20.3 18.3 15.8 18.0 21.8 6.4 8.9 4.1 20.5 19.1 21.4 23.6 10.4 6.8 22.4 15.3 9.3 14.2 10.4 9.2 17.7 3.8 12.7 27.7 14.9 12.5 14.3 21.8 9.6 8.9 31.1 13.1 15.8 9.8 27.8 15.4 10.4 21.6 8.8 12.9 2.4 16.4 3.2 2.8 1.9 4.6 2.4 8.4 0.8 0.6 1.5 4.2 3.8 4.6 1.4 1.8 9.5 10.7 0.4 14.8 10.5 20.2 4.5 3.2 0.2 5.0 0.4 23.7 0.0 11.6 4.9 5.3 4.1 4.5 14.0 2.4 5.0 4.7 1.9 1.4 0.2 8.4 1.8 10.3 15.7 7.9 0.5 6.8 14.8 1.7 14.1 3.9 10.7 0.5 0.5 9.8 1.0 18.6 11.0 6.8 6.5 4.9 7.4 8.2 5.2 14.3 8.4 2.4 7.1 15.4 2.6 0.0 1.9 3.2 4.6 2.8 3.0 1.2 2.2 3.7 2.3 2.4 1.6 2.3 1.1 1.9 2.7 16.4 1.6 2.4 8.8 9.5 5.3 8.7 8.9 4.1 10.4 6.8 9.2 9.8 PARP11 C12orf6 ENSG00000111224 "Poly(ADP-ribose) polymerase family member 11" Q9NR21 12 3791047-3873448 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA transport, Protein transport, Spermatogenesis, Translocation, Transport" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026895 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA026895: AB_1854980" "unprognostic (9.58e-2)" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (4.12e-2)" "unprognostic (6.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.53e-1)" "unprognostic (2.61e-1)" "unprognostic (3.58e-2)" "unprognostic (2.32e-2)" "unprognostic (2.50e-1)" "unprognostic (2.11e-1)" "unprognostic (7.52e-2)" "unprognostic (3.81e-2)" "unprognostic (2.87e-2)" 7.1 14.5 11.2 8.6 9.2 3.7 8.3 11.0 9.1 6.4 5.4 5.6 4.8 4.9 10.2 7.5 5.0 6.3 5.6 5.1 6.1 5.7 5.7 5.7 6.3 12.8 5.0 5.7 13.1 6.6 10.0 10.4 4.1 7.6 12.0 5.7 7.2 6.6 6.0 4.1 3.9 6.5 7.2 6.1 9.2 4.2 12.8 5.6 16.9 12.3 2.7 12.1 8.3 5.8 10.7 10.2 18.3 10.2 8.2 12.5 7.1 2.5 2.1 13.6 2.1 4.3 6.9 3.8 3.0 5.1 5.3 5.3 7.8 2.0 7.4 1.9 6.6 2.1 4.5 4.5 8.6 14.9 4.5 10.6 0.0 5.7 4.9 7.1 4.0 5.5 3.5 4.2 11.8 3.9 2.8 6.0 7.4 3.5 3.8 2.7 5.0 0.3 7.6 9.3 1.7 2.5 5.7 0.9 3.1 2.9 2.6 3.9 0.5 6.5 7.7 4.6 4.5 7.0 4.0 2.9 6.3 10.5 4.4 4.0 1.2 18.3 10.2 10.2 9.2 8.5 12.5 10.7 10.2 6.7 10.2 10.1 11.7 9.4 10.2 8.2 6.4 8.9 4.3 7.1 11.2 9.2 11.0 9.1 6.1 5.7 5.0 5.7 7.6 5.6 PARP12 "FLJ22693, PARP-12, ZC3H1, ZC3HDC1" ENSG00000059378 "Poly(ADP-ribose) polymerase family member 12" Q9H0J9 7 140023744-140063721 "Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 11.9" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003584, HPA063872" Approved Approved Nucleoplasm Nucleoplasm "HPA003584: AB_1079568, HPA063872: " "unprognostic (1.46e-3)" "unprognostic (2.93e-2)" "unprognostic (1.73e-1)" "unprognostic (2.71e-2)" "unprognostic (6.74e-2)" "unprognostic (1.42e-1)" "prognostic unfavourable (1.63e-4)" "unprognostic (2.30e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (7.51e-3)" "unprognostic (2.68e-1)" "prognostic unfavourable (4.12e-7)" "unprognostic (3.31e-2)" "unprognostic (2.76e-1)" "unprognostic (1.75e-2)" "unprognostic (6.01e-2)" 3.1 1.8 1.0 3.7 0.9 6.1 2.5 0.1 0.7 2.1 2.2 4.2 2.8 4.2 2.1 2.5 3.1 1.7 1.0 1.0 3.1 3.0 5.2 3.8 1.0 3.2 2.7 2.5 3.3 3.4 2.8 3.9 4.3 1.4 0.9 8.6 4.4 1.5 1.3 6.0 2.3 5.7 3.2 2.7 1.9 3.1 1.0 1.3 3.4 2.0 2.3 3.3 2.4 3.7 2.3 0.0 0.4 1.1 0.4 3.8 0.6 0.5 4.6 7.8 2.7 3.5 1.7 2.8 1.1 3.7 1.5 4.3 1.3 4.6 4.6 1.4 1.3 1.7 2.0 0.4 1.4 1.5 2.5 2.0 4.2 4.9 4.1 2.3 0.0 2.9 4.4 11.9 0.2 6.8 2.0 0.0 0.0 2.0 2.3 1.4 0.0 2.4 1.1 3.4 0.6 0.9 9.4 1.5 2.1 0.5 3.4 0.1 0.1 0.4 0.9 5.8 0.8 0.7 2.0 2.2 2.9 1.7 1.1 0.3 1.9 2.9 1.3 1.0 0.6 1.9 3.4 2.3 1.9 0.7 3.3 2.4 PARP14 "KIAA1268, pART8" ENSG00000173193 "Poly(ADP-ribose) polymerase family member 14" Q460N5 3 122680618-122730840 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 29.2;BJ hTERT+ SV40 Large T+ RasG12V: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008846, HPA012063" Supported Supported Cytosol Cytosol "HPA008846: AB_1854982, HPA012063: AB_1854981" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (4.20e-2)" "unprognostic (1.74e-3)" "unprognostic (1.62e-2)" "prognostic unfavourable (1.79e-4)" "unprognostic (7.87e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-3)" "unprognostic (1.71e-2)" 21.6 10.3 5.6 15.8 7.2 11.7 9.3 2.3 6.0 11.6 13.3 5.9 6.4 11.4 10.6 12.7 11.7 7.2 10.0 6.5 5.2 4.8 13.7 21.5 26.0 16.7 7.3 5.2 10.0 6.7 7.2 6.8 17.5 6.3 12.3 6.7 7.5 8.5 5.5 5.2 5.7 22.3 11.9 6.8 29.7 7.6 4.6 4.9 18.7 20.4 6.4 18.9 12.8 12.4 15.9 4.2 20.8 10.5 7.4 7.0 2.8 5.9 4.9 3.1 3.3 4.4 10.6 0.0 2.3 15.5 29.2 45.1 2.6 11.7 0.0 9.7 5.1 4.6 4.6 4.7 6.0 9.0 0.5 5.4 2.3 4.0 10.8 2.4 2.7 6.4 2.4 5.1 2.0 12.6 2.5 8.8 1.0 3.0 9.1 1.6 0.4 4.2 12.7 3.2 1.6 7.1 6.1 0.2 0.0 5.9 1.3 6.6 2.2 4.3 8.6 1.5 3.9 0.9 2.1 3.4 0.6 1.0 4.7 5.7 2.7 8.3 8.2 4.0 6.9 10.5 6.0 10.2 3.8 4.5 4.2 15.9 3.2 3.4 20.8 7.4 9.3 0.6 7.0 2.8 5.6 7.2 2.3 6.0 5.2 4.8 7.3 5.2 6.3 4.9 PARP15 "FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577602-122639047 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.9;lymphoid tissue: 40.4" "Cell line enhanced" "Detected in some" "HEL: 10.7;REH: 5.0;THP-1: 5.1;TIME: 12.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 9.3;MAIT T-cell: 6.5;memory B-cell: 11.2;memory CD4 T-cell: 5.0;memory CD8 T-cell: 6.4;naive B-cell: 11.9;naive CD4 T-cell: 4.3;naive CD8 T-cell: 5.9;NK-cell: 5.2;T-reg: 4.5" "Group enriched" "Detected in many" 6 "B-cells: 11.9;NK-cells: 5.2;T-cells: 9.3" "Low region specificity" "Detected in many" HPA035757 Approved Mitochondria "Intracellular and membrane" Mitochondria "HPA035757: AB_10669656" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" 2.4 0.9 0.5 24.5 0.4 9.8 1.3 0.3 0.8 1.2 2.8 1.2 0.5 1.0 1.5 2.3 1.9 1.4 2.8 1.5 0.6 0.5 1.5 1.9 5.6 20.3 0.6 0.6 1.1 2.7 0.0 1.0 1.0 0.6 1.3 2.1 1.8 5.5 0.2 2.6 0.7 22.9 0.9 0.9 40.4 1.7 1.7 0.4 9.4 1.9 1.7 34.8 3.6 1.2 11.9 1.2 1.3 0.6 5.2 9.3 2.7 0.6 0.2 0.5 0.5 0.2 0.3 0.6 0.3 0.2 0.1 0.1 0.3 1.0 0.8 0.6 0.2 0.6 0.1 0.0 0.0 1.9 0.2 10.7 0.8 0.5 0.2 0.7 0.5 2.2 0.1 0.4 0.2 2.4 0.3 2.1 0.0 0.5 3.2 0.7 0.7 0.3 5.0 0.4 0.6 0.0 1.0 0.8 0.5 0.3 0.2 0.3 0.8 5.1 12.7 0.4 1.1 0.5 0.4 1.0 0.7 2.4 0.7 0.3 0.2 1.3 0.2 0.1 9.3 0.5 6.5 11.2 5.0 6.4 0.9 11.9 4.3 5.9 0.7 5.2 0.6 1.2 4.5 2.7 0.5 0.4 0.3 0.8 0.6 0.5 0.6 0.6 0.6 0.4 PARP16 "C15orf30, FLJ20509, FLJ25281, pART15" ENSG00000138617 "Poly(ADP-ribose) polymerase family member 16" Q8N5Y8 15 65234460-65300618 "Enzymes, Predicted membrane proteins" "Unfolded protein response" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017081 Approved "HPA017081: AB_10963218" "unprognostic (1.17e-2)" "unprognostic (6.51e-3)" "unprognostic (2.82e-2)" "unprognostic (6.37e-2)" "unprognostic (7.38e-2)" "unprognostic (2.88e-2)" "unprognostic (3.05e-2)" "unprognostic (6.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.78e-1)" "unprognostic (3.41e-3)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-1)" "unprognostic (9.61e-2)" 8.9 14.2 12.0 13.1 11.6 8.0 20.4 32.2 17.7 18.6 12.8 5.6 11.9 9.3 13.1 8.5 10.5 12.0 8.7 7.2 9.7 5.3 9.0 18.1 11.5 14.0 11.5 6.2 17.6 11.3 12.7 8.5 9.2 9.1 11.5 10.4 7.5 10.3 21.4 5.4 10.8 9.7 17.7 8.0 9.3 11.0 7.6 12.0 15.1 9.5 6.3 12.4 14.0 25.6 10.1 4.4 14.1 5.3 10.3 14.2 6.0 3.8 4.0 4.4 6.9 3.6 3.8 1.9 1.7 4.7 5.0 5.2 3.2 3.5 12.5 4.9 2.2 6.3 20.3 2.5 3.7 4.5 8.1 2.1 4.3 4.5 6.8 5.7 4.0 4.4 4.2 1.3 5.1 4.6 5.1 4.8 4.3 4.6 11.8 6.1 2.0 5.4 21.9 8.0 9.5 3.5 3.5 7.6 5.1 5.5 5.3 4.5 6.2 5.2 1.8 5.9 4.5 3.3 2.7 8.9 10.5 16.4 4.9 8.5 2.7 14.1 3.3 10.0 11.6 5.3 12.9 7.8 11.2 11.8 4.4 10.1 14.2 10.5 13.0 10.3 5.2 3.9 9.2 6.0 12.0 11.6 32.2 17.7 9.7 5.3 11.5 6.2 9.1 12.0 PARP2 ADPRTL2 ENSG00000129484 "Poly(ADP-ribose) polymerase 2" Q9UGN5 14 20343582-20357905 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052003 Approved Supported Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA052003: " "unprognostic (3.93e-1)" "unprognostic (7.92e-2)" "unprognostic (4.12e-1)" "unprognostic (1.24e-1)" "unprognostic (3.40e-2)" "unprognostic (7.30e-2)" "prognostic unfavourable (6.48e-4)" "unprognostic (1.97e-2)" "unprognostic (4.43e-2)" "unprognostic (9.35e-3)" "unprognostic (1.44e-2)" "unprognostic (1.42e-2)" "unprognostic (3.37e-3)" "unprognostic (2.83e-1)" "unprognostic (9.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.89e-2)" 11.5 16.6 23.6 8.9 28.5 20.9 15.2 36.7 31.3 12.0 11.7 16.8 9.3 11.2 18.8 16.8 10.7 14.7 8.9 14.0 19.2 17.8 14.0 15.0 12.0 11.8 16.6 30.8 20.2 11.8 11.6 14.6 11.3 22.1 11.3 12.9 10.8 10.5 12.9 25.9 15.1 10.8 14.6 13.9 11.4 11.6 20.4 17.4 6.0 11.7 13.9 15.2 9.3 10.4 6.7 5.6 1.8 5.0 6.9 12.3 4.9 20.2 14.8 22.8 17.1 7.6 7.2 16.6 22.5 12.3 28.6 35.5 13.9 19.4 15.0 10.2 7.1 19.0 30.3 10.3 33.9 12.0 14.8 13.7 17.9 23.3 6.8 28.3 7.9 5.0 8.8 17.8 19.7 14.7 14.5 20.5 19.6 12.5 14.5 12.2 12.5 23.1 18.2 31.0 9.7 11.4 10.6 15.8 10.9 25.1 14.0 6.6 12.9 9.6 10.0 17.5 26.5 12.0 18.2 19.2 24.5 19.9 7.3 12.6 19.3 1.8 5.0 0.5 9.5 4.5 12.3 6.7 8.9 8.3 5.4 4.6 9.6 9.3 0.1 6.9 2.5 5.6 5.2 4.9 23.6 28.5 36.7 31.3 19.2 17.8 16.6 30.8 22.1 17.4 PARP3 "ADPRT3, ADPRTL3, hPARP-3, IRT1, pADPRT-3" ENSG00000041880 "Poly(ADP-ribose) polymerase family member 3" Q9Y6F1 3 51942345-51948867 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020984, HPA067657" Supported Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA020984: , HPA067657: " "prognostic favourable (6.39e-5)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (2.85e-2)" "unprognostic (7.31e-2)" "unprognostic (1.56e-1)" "unprognostic (4.13e-1)" "unprognostic (3.53e-2)" "unprognostic (2.26e-1)" "unprognostic (2.01e-1)" "unprognostic (7.44e-3)" "unprognostic (4.30e-1)" "prognostic favourable (1.25e-8)" "unprognostic (5.63e-2)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-3)" 15.2 29.2 11.2 14.6 17.1 2.8 13.6 5.7 18.8 7.5 17.3 10.6 14.3 26.9 10.3 14.1 10.8 12.1 16.2 12.4 11.6 12.3 17.3 22.3 13.3 9.7 12.0 14.2 8.2 3.9 34.2 9.8 6.2 12.2 12.1 10.7 13.2 14.0 18.1 14.6 6.1 26.3 18.9 8.7 12.8 15.8 4.5 10.2 2.9 17.0 9.6 10.3 15.1 8.9 9.0 2.9 1.7 4.1 6.6 4.9 2.3 6.0 3.3 1.0 9.0 8.7 16.5 2.5 9.8 15.9 12.2 13.7 1.9 15.9 8.2 2.6 16.2 0.9 2.5 8.9 5.9 20.0 0.6 4.2 6.7 6.3 9.5 2.5 5.8 13.1 5.5 7.7 5.2 6.1 1.7 7.7 9.3 1.5 2.2 6.3 1.3 9.6 3.5 1.5 7.0 7.4 6.6 1.0 3.4 9.9 2.8 5.3 3.4 2.8 13.7 24.5 5.1 3.6 5.9 11.8 14.3 3.5 15.8 7.4 7.6 0.0 2.6 1.7 3.6 4.1 3.4 9.0 4.2 2.8 2.9 4.3 4.9 4.9 0.1 6.6 2.0 1.2 4.3 2.3 11.2 17.1 5.7 18.8 11.6 12.3 12.0 14.2 12.2 10.2 PARP4 "ADPRTL1, p193, VAULT3, VPARP, VWA5C" ENSG00000102699 "Poly(ADP-ribose) polymerase family member 4" Q9UKK3 13 24420926-24512810 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Ribonucleoprotein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011739 Approved Supported Cytosol Cytosol "HPA011739: AB_1854986" "unprognostic (1.61e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-2)" "unprognostic (4.35e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (2.52e-1)" "unprognostic (2.45e-1)" "unprognostic (2.02e-2)" "unprognostic (4.12e-3)" "unprognostic (2.97e-2)" "prognostic favourable (1.21e-5)" "unprognostic (3.23e-2)" "unprognostic (1.71e-1)" "unprognostic (3.80e-2)" "unprognostic (2.84e-3)" 25.3 24.7 6.6 16.7 12.9 11.6 14.6 2.3 7.0 17.8 39.4 16.7 21.6 22.9 19.1 11.2 22.2 14.9 23.8 11.3 7.9 5.6 28.8 17.3 17.8 16.5 14.6 4.4 15.9 15.5 11.2 12.6 14.8 12.5 16.1 24.1 14.0 17.7 30.9 6.5 10.2 49.9 15.5 20.5 28.4 20.4 7.0 12.1 28.8 18.2 11.3 26.2 23.3 13.2 9.0 16.4 26.1 18.6 11.8 12.9 10.6 15.0 13.5 6.6 11.9 18.3 26.1 5.6 17.5 23.0 15.4 13.8 5.5 39.2 11.2 17.5 15.9 17.5 9.8 17.7 12.6 25.8 6.9 16.1 12.5 12.6 10.4 20.6 16.0 15.0 6.0 12.7 6.8 25.2 4.5 5.0 18.2 6.9 13.0 9.9 7.5 16.7 12.3 12.4 15.8 28.6 31.0 6.0 7.7 12.8 5.2 12.1 2.5 17.1 35.7 7.0 7.3 8.9 17.8 5.7 6.6 14.8 12.7 10.9 15.2 25.2 12.4 26.1 12.9 15.3 12.9 9.0 10.8 12.8 16.4 5.1 8.1 9.6 14.3 11.8 18.6 6.2 12.7 10.6 6.6 12.9 2.3 7.0 7.9 5.6 14.6 4.4 12.5 12.1 PARP6 pART17 ENSG00000137817 "Poly(ADP-ribose) polymerase family member 6" Q2NL67 15 72241181-72272999 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026991 Approved Approved "Plasma membrane" "Plasma membrane" "HPA026991: AB_1854989" "unprognostic (3.88e-2)" "prognostic favourable (3.17e-5)" "prognostic unfavourable (3.37e-4)" "unprognostic (3.36e-1)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (2.37e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (2.64e-1)" "unprognostic (8.55e-2)" "unprognostic (6.92e-2)" "prognostic unfavourable (8.02e-8)" "unprognostic (6.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "unprognostic (4.42e-2)" 13.7 16.6 28.0 12.8 32.4 25.1 26.5 46.6 41.2 15.5 16.2 16.9 18.2 14.1 23.3 23.8 14.0 17.0 20.2 18.4 26.1 22.4 14.3 9.0 15.7 16.8 19.9 21.8 26.3 20.9 20.6 30.8 17.0 19.4 19.3 14.3 14.5 21.3 18.8 23.9 20.3 14.4 19.6 14.2 18.2 18.2 25.1 15.8 9.6 21.7 12.5 15.8 16.3 15.8 4.1 4.0 12.1 5.3 4.3 4.3 2.9 7.2 13.1 13.8 17.9 14.8 12.4 11.2 6.2 9.4 10.3 15.2 8.6 13.2 10.0 3.9 9.4 9.5 15.2 8.4 5.9 11.8 13.7 14.5 22.9 0.1 12.4 7.4 13.9 15.9 20.8 9.6 26.6 6.9 7.3 11.5 8.3 13.2 6.3 13.1 6.4 0.0 11.8 9.8 7.8 9.6 14.4 39.0 20.7 10.4 8.5 17.0 10.8 8.6 6.5 13.0 11.9 16.9 9.4 13.0 11.9 10.8 9.4 14.6 9.0 1.7 5.3 12.1 3.8 4.4 2.7 3.3 2.7 4.0 4.0 4.1 4.3 3.2 5.7 4.3 4.9 3.1 4.2 2.9 28.0 32.4 46.6 41.2 26.1 22.4 19.9 21.8 19.4 15.8 PARP8 "FLJ21308, pART16" ENSG00000151883 "Poly(ADP-ribose) polymerase family member 8" Q8N3A8 5 50665899-50846522 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "THP-1: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049183 Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Nucleoplasm "Midbody ring, Cytosol" "HPA049183: " "unprognostic (1.22e-2)" "unprognostic (2.53e-1)" "unprognostic (1.77e-1)" "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (6.33e-2)" "unprognostic (8.86e-3)" "unprognostic (7.27e-2)" "unprognostic (1.86e-2)" "unprognostic (8.96e-2)" "unprognostic (2.85e-1)" "unprognostic (6.81e-2)" "unprognostic (9.63e-2)" "unprognostic (2.84e-2)" "unprognostic (4.42e-2)" "unprognostic (4.23e-2)" "prognostic favourable (1.12e-4)" 6.2 7.8 8.8 17.1 9.5 33.5 5.3 2.4 18.7 5.6 5.5 3.3 0.6 6.8 5.2 5.4 5.2 7.4 12.3 3.6 12.8 8.0 5.8 4.2 10.9 18.2 4.9 11.0 5.9 7.1 9.8 14.4 5.6 5.4 6.1 4.3 4.1 7.6 4.2 1.7 4.2 14.2 5.4 7.0 20.1 10.2 6.4 2.8 9.9 21.9 1.1 12.3 8.8 7.0 7.1 3.9 13.1 5.9 15.5 32.0 9.5 11.7 0.0 5.4 8.6 1.5 2.7 8.6 1.9 7.0 1.9 5.6 0.3 15.4 6.9 8.2 0.2 5.8 0.9 5.9 4.5 9.7 7.5 5.1 4.7 0.5 2.9 11.9 0.1 3.3 4.9 3.8 2.7 0.1 0.7 4.2 2.6 3.8 14.3 15.1 5.8 2.9 7.2 11.5 8.0 3.5 5.8 6.0 9.3 6.3 10.3 1.6 0.4 42.2 0.0 0.4 7.3 0.5 5.7 3.1 0.1 13.5 6.5 3.4 8.0 10.3 5.9 13.1 20.6 1.6 32.0 6.0 16.1 23.0 3.9 7.1 10.0 16.7 12.3 15.5 1.1 1.8 9.5 9.5 8.8 9.5 2.4 18.7 12.8 8.0 4.9 11.0 5.4 2.8 PARP9 "BAL, BAL1" ENSG00000138496 "Poly(ADP-ribose) polymerase family member 9" Q8IXQ6 3 122527924-122564577 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 34.9;BJ hTERT+ SV40 Large T+ RasG12V: 41.8;SK-MEL-30: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066708 Supported Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Cytosol" Mitochondria "HPA066708: " "unprognostic (3.06e-2)" "unprognostic (4.80e-2)" "unprognostic (1.55e-3)" "unprognostic (6.70e-3)" "unprognostic (1.11e-1)" "unprognostic (6.38e-2)" "unprognostic (4.73e-3)" "unprognostic (3.39e-3)" "unprognostic (1.31e-1)" "prognostic favourable (6.65e-4)" "unprognostic (1.00e-3)" "unprognostic (5.63e-3)" "unprognostic (1.56e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-2)" "unprognostic (9.65e-3)" "unprognostic (1.56e-2)" 27.1 20.2 8.7 17.2 12.4 9.1 13.8 2.9 13.9 13.1 13.1 9.9 7.4 10.4 23.3 10.1 15.6 12.3 14.9 8.5 7.4 6.0 17.8 38.6 18.9 17.5 8.5 6.0 12.1 14.4 16.0 20.3 11.9 10.3 15.1 10.1 11.5 19.1 6.6 8.6 5.7 21.2 14.8 16.3 27.3 11.1 5.4 10.3 21.8 17.5 9.0 19.1 13.7 9.8 7.3 11.9 38.2 18.0 13.0 10.6 9.1 8.0 2.7 1.0 0.7 6.2 13.0 0.9 2.7 14.7 34.9 41.8 4.2 8.9 1.8 6.0 5.4 8.9 2.3 4.8 7.3 13.9 1.6 8.7 2.8 2.2 6.7 2.8 5.8 10.5 4.7 4.9 1.2 7.4 0.8 7.5 1.4 3.5 8.9 3.5 0.4 7.6 9.5 9.9 0.6 13.4 4.6 0.6 2.4 7.1 1.2 32.3 3.8 3.1 4.4 1.5 4.4 0.3 1.6 4.6 2.4 3.3 5.2 3.0 2.7 14.4 12.7 15.3 9.2 17.7 8.6 7.3 9.8 10.3 11.9 5.0 7.5 9.1 38.2 13.0 18.0 1.4 10.6 9.1 8.7 12.4 2.9 13.9 7.4 6.0 8.5 6.0 10.3 10.3 PARS2 DKFZp727A071 ENSG00000162396 "Prolyl-tRNA synthetase 2, mitochondrial" Q7L3T8 1 54756898-54764514 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028308, HPA028314, HPA028518" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" "Nucleoli fibrillar center, Mitochondria" "HPA028308: , HPA028314: AB_10603981, HPA028518: " "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "prognostic favourable (1.26e-5)" "unprognostic (1.93e-2)" "unprognostic (1.19e-2)" "unprognostic (1.79e-3)" "prognostic unfavourable (2.34e-4)" "unprognostic (6.48e-2)" "unprognostic (2.72e-1)" "unprognostic (1.14e-1)" "unprognostic (9.42e-2)" "unprognostic (1.10e-1)" "prognostic favourable (1.24e-6)" "unprognostic (2.72e-2)" "unprognostic (9.77e-2)" "unprognostic (1.73e-2)" "unprognostic (9.64e-2)" 6.8 8.4 4.7 4.0 8.2 0.5 6.2 5.2 7.9 6.5 9.0 9.5 8.3 6.0 7.9 7.5 7.0 10.4 4.1 6.6 6.5 4.4 9.6 11.3 4.1 5.8 4.5 5.3 11.5 13.6 7.0 6.6 5.6 4.9 7.1 8.3 5.0 7.2 6.9 8.7 6.7 5.1 4.9 4.3 4.9 6.2 11.5 9.4 8.7 6.7 5.9 5.2 6.0 5.2 7.3 8.9 5.3 11.6 8.1 10.5 6.0 4.7 7.8 5.1 6.7 6.3 5.4 11.5 4.0 5.0 7.2 5.2 9.0 3.1 8.3 6.4 3.6 7.7 9.2 6.4 5.4 5.4 8.4 8.0 4.8 6.7 9.8 4.6 2.8 5.8 9.8 9.3 8.4 5.3 14.0 1.1 5.5 5.0 6.4 6.1 11.8 10.1 5.0 10.1 9.6 6.1 3.5 5.3 5.4 5.8 7.7 10.5 4.4 5.9 2.8 5.4 5.6 7.6 5.0 8.2 6.9 3.3 4.1 5.5 3.1 1.5 6.6 5.3 6.4 9.7 7.6 6.1 7.0 6.8 8.9 7.3 10.5 7.0 0.6 8.1 11.6 7.1 9.3 6.0 4.7 8.2 5.2 7.9 6.5 4.4 4.5 5.3 4.9 9.4 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.1;testis: 22.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 24.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA016450, HPA021079" Uncertain Supported Cytosol Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.5 1.1 2.4 10.3 24.1 8.9 3.1 6.3 5.2 2.2 2.1 2.2 2.1 3.8 2.9 6.7 3.1 7.2 3.3 1.1 2.9 2.7 3.7 1.3 3.0 14.5 1.3 1.6 1.9 3.3 4.4 4.9 1.1 3.6 12.1 2.8 4.7 2.7 1.8 2.0 4.9 3.9 1.4 1.6 4.4 3.4 22.0 7.2 9.0 4.8 1.9 9.9 2.7 1.9 7.1 1.1 4.8 1.0 2.7 6.0 3.0 4.9 6.7 9.1 11.5 0.7 1.4 12.1 4.8 1.5 4.4 6.2 5.4 5.0 2.6 1.0 1.1 12.5 10.3 4.1 3.2 10.4 9.7 7.1 12.4 9.6 0.5 9.7 11.2 0.6 3.3 4.6 1.3 3.1 9.2 3.5 3.1 5.6 11.5 10.2 10.1 4.1 18.3 9.2 3.2 1.7 11.2 16.1 4.9 2.8 5.5 2.1 4.6 7.0 4.1 6.1 5.5 7.7 6.4 4.8 4.8 12.2 3.8 7.3 5.6 4.8 1.0 0.7 1.7 0.6 1.5 7.1 5.9 5.3 1.1 6.6 3.7 3.9 1.3 2.7 1.0 0.7 6.0 3.0 2.4 24.1 6.3 5.2 2.9 2.7 1.3 1.6 3.6 7.2 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809620-27838095 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 19.4;testis: 67.9" "Cell line enhanced" "Detected in many" "A-431: 60.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.1;T-reg: 1.6" "Group enriched" "Detected in many" 10 "NK-cells: 2.1;T-cells: 1.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavourable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavourable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 0.6 0.8 0.2 7.7 0.3 3.3 1.3 0.3 0.4 1.1 3.8 0.3 0.2 3.7 0.4 0.6 6.2 0.3 0.8 3.3 0.3 0.2 0.7 0.9 1.2 5.4 0.3 0.2 0.4 0.4 0.0 0.2 2.2 0.3 0.4 4.6 0.2 1.1 0.2 0.4 1.9 3.6 0.9 0.6 1.7 1.7 67.9 0.2 19.4 0.3 4.7 5.3 0.7 1.9 0.1 0.0 0.0 0.0 2.1 1.6 0.5 60.7 19.8 19.5 12.3 1.9 3.4 8.2 27.9 13.3 28.8 24.3 6.9 11.3 32.4 9.9 10.7 16.1 18.7 9.4 31.6 7.9 10.2 7.8 14.1 10.0 0.1 5.0 11.6 0.9 7.7 13.3 7.1 14.5 11.4 21.8 33.9 6.9 19.2 5.9 3.5 17.2 12.0 27.2 8.7 10.8 9.4 7.7 12.1 10.4 12.2 15.6 12.9 7.7 8.4 18.9 45.6 23.9 29.6 3.1 8.6 15.0 11.5 8.9 40.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 1.6 0.5 0.2 0.3 0.3 0.4 0.3 0.2 0.3 0.2 0.3 0.2 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848233-66958376 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 41.1;liver: 76.0" "Cell line enhanced" "Detected in many" "HeLa: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 3.8;T-cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria 96000 Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavourable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favourable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 41.1 10.7 11.1 2.8 14.6 3.1 12.9 13.1 14.9 2.4 3.8 10.7 21.4 5.6 2.1 2.4 5.0 2.7 2.9 4.0 11.3 8.9 18.7 76.0 2.1 1.6 15.5 11.5 4.4 4.3 19.4 4.0 4.1 10.9 5.4 3.1 3.4 24.2 24.4 5.7 2.8 6.7 1.8 9.4 1.5 3.3 6.1 13.1 0.6 4.2 2.5 2.5 2.2 2.1 0.6 2.6 0.0 3.8 0.3 2.9 2.0 2.9 8.9 3.3 8.1 13.7 5.4 3.5 1.8 7.8 3.5 3.4 4.4 3.2 0.0 3.7 2.9 3.8 3.7 20.6 1.0 1.7 5.2 4.4 27.7 17.0 10.7 0.0 5.7 20.6 5.3 2.8 6.4 2.9 8.4 0.0 1.2 19.0 5.0 2.4 6.3 7.4 3.7 6.9 1.8 3.2 0.9 7.2 10.2 17.3 9.2 7.0 7.5 1.2 3.2 3.9 3.6 4.6 2.0 1.9 2.2 0.0 4.0 2.8 3.3 0.0 3.8 0.0 1.2 0.9 1.4 0.2 0.5 1.9 2.6 0.6 2.9 1.6 0.0 0.3 0.5 1.0 1.5 2.0 11.1 14.6 13.1 13.6 11.3 8.9 15.5 11.5 10.9 13.1 PCBD1 "DCOH, PCBD, PCD" ENSG00000166228 "Pterin-4 alpha-carbinolamine dehydratase 1" P61457 10 70882280-70888784 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis, Transcription, Transcription regulation" "Activator, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.0" "Cell line enhanced" "Detected in many" "CACO-2: 67.5;Hep G2: 66.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037575, HPA061723" Approved Enhanced Nucleoplasm,Cytosol 210000 Nucleoplasm Cytosol "HPA037575: AB_10671761, HPA061723: " "unprognostic (1.02e-1)" "unprognostic (5.05e-2)" "unprognostic (7.43e-2)" "unprognostic (3.69e-1)" "unprognostic (5.39e-2)" "unprognostic (4.80e-3)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "unprognostic (2.40e-2)" "unprognostic (2.95e-1)" "unprognostic (5.63e-2)" "unprognostic (3.38e-2)" "unprognostic (9.26e-2)" "unprognostic (1.74e-1)" "unprognostic (5.76e-2)" "unprognostic (7.43e-3)" 18.3 25.5 18.1 9.6 15.6 4.3 19.7 13.2 14.8 13.9 18.4 7.8 24.3 12.6 13.9 21.4 26.5 25.6 22.9 32.5 10.8 23.7 38.7 99.0 14.0 7.8 16.7 12.3 18.5 73.0 15.8 15.5 11.7 16.4 26.9 20.3 16.3 16.2 20.7 23.1 5.8 17.2 18.1 14.5 10.2 19.2 7.0 8.7 4.3 36.8 16.2 12.3 22.4 31.8 11.8 20.9 3.5 19.4 8.0 16.9 7.5 20.4 48.5 2.9 30.1 11.0 10.3 3.9 6.6 11.0 10.3 8.2 67.5 36.2 4.2 19.2 7.2 13.6 18.3 10.6 7.0 10.9 33.1 3.7 7.7 66.3 11.6 3.6 13.6 10.0 11.6 10.2 4.8 27.6 7.2 0.3 7.1 34.1 0.4 12.2 4.1 45.4 2.0 4.0 13.4 43.2 21.1 12.7 21.5 5.5 37.6 14.3 10.9 7.1 11.4 1.7 14.4 2.5 16.2 0.1 0.8 0.1 9.4 11.9 2.6 0.0 10.7 3.5 8.8 19.4 6.9 11.8 11.6 12.6 20.9 4.1 3.8 7.9 0.6 8.0 13.3 15.3 16.9 7.5 18.1 15.6 13.2 14.8 10.8 23.7 16.7 12.3 16.4 8.7 PCBD2 "DCOH2, DCOHM" ENSG00000132570 "Pterin-4 alpha-carbinolamine dehydratase 2" Q9H0N5 5 134904906-135007959 "Enzymes, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 47.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036428 Uncertain Approved "Plasma membrane" "Plasma membrane" "HPA036428: AB_10670103" "unprognostic (3.70e-2)" "unprognostic (3.53e-2)" "unprognostic (3.54e-3)" "unprognostic (1.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" "unprognostic (4.22e-1)" "unprognostic (6.43e-2)" "unprognostic (4.49e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.57e-2)" "unprognostic (6.34e-2)" "unprognostic (9.32e-3)" "unprognostic (1.50e-1)" 4.9 8.1 5.4 7.0 6.6 6.6 5.3 3.0 4.4 3.9 8.7 6.5 9.4 8.0 6.5 8.4 9.3 4.9 6.9 13.8 5.0 5.3 9.2 9.8 6.5 5.0 5.6 5.2 5.1 12.9 9.6 6.1 4.8 6.8 4.7 6.4 9.6 14.2 7.9 47.0 6.7 12.7 7.6 7.0 5.5 7.1 5.5 5.8 5.3 8.3 13.5 8.1 5.6 5.5 8.2 11.5 7.2 10.1 6.3 6.6 4.3 7.7 7.5 8.0 6.0 5.6 4.7 5.9 6.2 4.8 3.5 3.6 13.9 19.8 9.2 10.4 4.2 5.3 5.4 5.9 3.3 12.9 3.6 5.3 7.9 8.3 5.4 6.0 3.8 2.5 5.8 3.7 8.5 4.1 7.6 13.9 6.2 15.9 6.3 10.2 4.5 7.3 10.0 7.5 8.2 6.5 6.5 6.0 7.9 9.3 4.8 7.7 13.4 7.9 4.5 6.8 5.1 5.9 7.8 10.8 14.8 6.3 6.1 7.3 4.4 2.7 10.1 7.2 5.1 6.3 5.0 8.2 6.3 5.3 8.6 8.2 5.4 5.3 3.3 6.3 6.1 11.5 6.6 4.3 5.4 6.6 3.0 4.1 5.0 5.3 5.6 5.2 6.8 5.8 PCCA ENSG00000175198 "Propionyl-CoA carboxylase alpha subunit" P05165 13 100089015-100530437 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Ligase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 106.7" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 53.2;SCLC-21H: 29.5;U-937: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041716, HPA047792" Enhanced Supported Mitochondria 120000 Mitochondria "HPA041716: , HPA047792: " "unprognostic (1.18e-1)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (4.71e-2)" "unprognostic (1.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.55e-1)" "unprognostic (5.90e-3)" "unprognostic (2.41e-1)" "unprognostic (1.55e-1)" "unprognostic (6.14e-2)" "unprognostic (1.42e-1)" "prognostic favourable (0.00e+0)" "unprognostic (7.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.32e-2)" 15.6 26.2 9.7 11.3 11.1 3.2 12.0 24.0 10.7 12.0 17.5 12.0 14.3 6.7 16.4 106.7 8.8 8.4 7.6 12.4 9.5 7.5 51.3 44.3 8.1 4.0 11.2 8.2 9.7 12.7 5.5 12.4 10.5 12.6 13.1 13.7 11.7 12.2 10.4 10.7 7.7 7.8 17.0 12.0 8.2 16.1 4.7 10.9 4.2 11.9 5.0 6.9 10.8 8.8 3.7 13.0 1.6 10.8 7.3 6.1 4.7 3.2 5.8 9.6 3.1 9.2 8.0 5.4 3.2 4.8 3.0 2.8 7.2 4.4 0.2 4.9 3.2 3.7 2.8 4.5 5.0 5.3 3.2 7.5 4.1 15.4 5.1 0.3 3.7 7.4 4.8 2.8 4.7 6.2 3.0 4.3 5.5 3.5 0.8 16.9 5.9 2.6 6.6 4.1 5.2 53.2 6.4 29.5 3.5 2.2 12.3 5.4 8.9 13.4 4.5 3.1 2.6 2.1 2.2 4.2 3.8 0.1 6.0 41.0 2.2 1.5 8.5 1.6 4.6 10.3 6.1 3.7 3.0 4.3 13.0 2.6 4.1 5.1 1.3 7.3 10.8 1.1 6.0 4.7 9.7 11.1 24.0 10.7 9.5 7.5 11.2 8.2 12.6 10.9 PCCB ENSG00000114054 "Propionyl-CoA carboxylase beta subunit" P05166 3 136250306-136337896 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036939, HPA036940" Enhanced "Intracellular and membrane" 79000 "HPA036939: AB_10671366, HPA036940: AB_10669779" "unprognostic (2.74e-1)" "unprognostic (7.88e-3)" "unprognostic (3.99e-2)" "unprognostic (2.89e-2)" "unprognostic (2.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.05e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-2)" "unprognostic (2.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "prognostic favourable (6.47e-7)" "unprognostic (2.43e-2)" "unprognostic (2.64e-1)" "unprognostic (3.50e-1)" "unprognostic (4.13e-1)" 13.0 46.0 14.3 7.7 16.3 12.7 11.8 7.8 19.2 8.1 17.5 21.0 11.6 15.3 7.1 6.4 11.8 8.1 12.5 36.7 14.1 12.6 36.0 80.2 7.7 8.7 18.9 16.4 6.8 20.8 16.2 9.6 10.0 22.3 10.2 17.6 10.0 10.9 10.6 30.5 8.0 11.1 14.1 18.6 7.9 11.5 17.6 15.5 6.3 15.7 12.4 8.1 9.6 6.6 12.4 24.6 3.9 16.6 12.8 14.9 11.5 20.2 14.5 13.9 20.8 10.6 11.7 24.6 10.7 11.6 16.2 23.0 21.5 14.3 25.3 29.9 15.0 11.3 16.3 14.4 24.7 15.0 13.8 44.3 17.1 32.4 22.6 34.0 19.7 13.8 13.8 10.3 23.6 18.2 32.2 13.6 12.4 38.6 33.6 20.0 11.7 13.1 9.3 11.5 36.1 29.8 22.2 27.8 20.7 27.0 16.0 24.5 31.9 20.2 13.6 8.2 8.7 22.9 9.4 25.9 21.3 21.1 11.6 13.2 9.5 2.8 16.2 3.9 13.2 16.6 14.9 12.4 8.8 13.6 24.6 10.2 9.0 11.1 1.4 12.8 14.6 21.2 7.9 11.5 14.3 16.3 7.8 19.2 14.1 12.6 18.9 16.4 22.3 15.5 PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568112 "Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 419.5" "Cell line enriched" "Detected in some" 10 "ASC diff: 21.5" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA006277, HPA006507, CAB017027" Approved 380000 "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favourable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" 10.0 0.1 0.4 2.2 0.4 0.0 11.1 0.2 0.6 0.1 52.0 0.2 0.1 19.2 0.1 0.7 0.2 0.1 5.6 0.4 0.3 0.2 72.0 419.5 0.2 0.3 0.2 0.2 0.4 0.2 0.0 5.0 0.1 0.5 0.2 14.0 0.2 0.2 0.1 0.3 0.1 58.5 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.4 0.4 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.6 0.3 0.2 0.2 0.2 0.5 0.2 PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "intestine: 156.3;liver: 115.1" "Cell line enhanced" "Detected in many" "HHSteC: 34.9;hTCEpi: 33.9;SK-MEL-30: 32.1" "Cancer enhanced" "Detected in all" "liver cancer: 91.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria 3300000 Mitochondria "CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (3.11e-1)" "unprognostic (2.10e-1)" "prognostic favourable (2.81e-4)" "unprognostic (3.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-1)" "unprognostic (3.71e-1)" "unprognostic (2.82e-2)" "unprognostic (1.17e-1)" 8.2 2.5 1.0 4.9 1.9 1.0 4.3 1.3 1.3 1.3 69.7 1.4 6.9 51.8 1.3 8.5 4.5 1.2 4.2 2.6 1.5 1.0 26.4 115.1 6.0 4.4 1.7 1.2 1.8 8.5 3.4 1.7 1.2 1.8 2.0 5.4 1.9 11.5 4.9 1.0 2.7 156.3 1.1 1.7 6.7 3.3 3.9 1.3 1.3 5.8 1.9 4.6 2.8 1.9 8.8 10.8 2.4 15.1 1.5 6.5 3.9 5.4 3.1 0.9 5.8 3.6 3.7 14.8 6.8 8.2 5.7 9.3 5.1 6.3 13.9 0.8 10.5 8.0 6.0 8.8 4.7 7.1 0.2 2.5 1.7 27.2 34.9 4.8 11.0 4.3 33.9 3.6 8.8 4.6 7.1 25.8 2.2 23.7 1.2 2.4 1.0 4.1 2.8 3.4 7.9 1.7 8.5 3.7 5.9 5.2 6.8 32.1 9.1 7.5 0.8 1.2 6.6 1.8 1.9 17.7 5.5 3.4 3.5 7.7 3.0 0.1 8.2 2.4 3.1 15.1 3.4 8.8 3.5 3.5 10.8 6.1 2.2 2.0 1.0 1.5 14.4 1.9 6.5 3.9 1.0 1.9 1.3 1.3 1.5 1.0 1.7 1.2 1.8 1.3 PCMT1 ENSG00000120265 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase" P22061 6 149749443-149811420 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003239 Approved Supported Cytosol 8200000 Cytosol "HPA003239: AB_1079580" "prognostic unfavourable (4.02e-7)" "prognostic unfavourable (9.58e-4)" "unprognostic (1.35e-2)" "prognostic unfavourable (4.27e-4)" "unprognostic (1.02e-1)" "prognostic unfavourable (1.88e-4)" "prognostic unfavourable (2.58e-4)" "unprognostic (1.91e-2)" "unprognostic (1.58e-2)" "unprognostic (9.02e-2)" "unprognostic (6.45e-2)" "unprognostic (6.77e-2)" "unprognostic (6.14e-2)" "unprognostic (4.38e-1)" "unprognostic (1.70e-1)" "unprognostic (2.17e-2)" "prognostic unfavourable (6.38e-4)" 19.1 18.4 35.7 13.0 43.0 28.5 19.3 33.5 58.3 20.2 16.9 19.2 12.4 14.7 16.0 22.2 17.9 15.8 11.0 43.9 35.0 38.8 21.3 29.5 15.1 14.6 35.1 46.0 16.2 14.6 16.4 15.5 17.2 57.4 22.1 18.1 11.6 17.2 21.4 69.5 14.7 13.6 19.6 28.6 12.0 12.7 29.1 19.2 18.1 19.3 15.9 17.9 14.4 13.7 31.6 53.0 51.2 58.0 30.0 37.4 51.6 21.4 17.0 17.4 21.8 37.5 31.0 19.4 35.3 20.2 28.1 35.5 49.3 16.4 27.2 30.0 29.8 26.8 29.9 35.2 40.6 18.9 43.3 41.5 32.0 48.2 25.1 49.4 51.1 15.4 26.1 32.0 34.6 26.5 59.3 26.7 33.5 63.9 24.0 37.7 14.2 19.1 19.9 22.6 19.5 27.3 15.8 33.2 12.8 26.8 42.8 22.9 25.9 35.2 19.7 16.6 21.0 31.4 38.3 16.9 26.2 27.8 26.1 33.0 32.8 40.0 58.0 51.2 30.2 53.6 30.1 31.6 30.6 32.7 53.0 24.2 28.5 32.5 30.8 30.0 52.2 23.9 37.4 51.6 35.7 43.0 33.5 58.3 35.0 38.8 35.1 46.0 57.4 19.2 PCSK1 "NEC1, PC1, PC3, SPC3" ENSG00000175426 "Proprotein convertase subtilisin/kexin type 1" P29120 5 96390415-96434143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.6" "Group enriched" "Detected in some" 6 "SCLC-21H: 18.5;U-138 MG: 15.8;U-87 MG: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "basophil: 1.8" "Lineage enhanced" "Detected in single" "granulocytes: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048564 Approved "Secreted in other tissues" "HPA048564: " "unprognostic (1.86e-2)" "unprognostic (2.13e-2)" "unprognostic (4.66e-3)" "unprognostic (8.20e-5)" "prognostic unfavourable (9.13e-5)" "unprognostic (8.47e-4)" "unprognostic (1.46e-1)" "unprognostic (5.84e-3)" "unprognostic (4.71e-1)" "unprognostic (3.07e-3)" "unprognostic (1.89e-3)" "unprognostic (1.01e-1)" "unprognostic (7.90e-6)" "unprognostic (5.25e-2)" "unprognostic (9.96e-2)" "unprognostic (1.33e-3)" "unprognostic (9.37e-3)" 2.3 8.5 1.3 6.0 10.1 0.5 1.3 0.5 36.6 1.2 3.3 0.5 0.0 6.7 0.5 8.8 0.4 0.4 0.6 1.0 2.8 27.1 0.5 0.4 0.8 0.4 3.1 14.0 0.6 9.8 0.3 10.9 0.4 7.5 0.5 3.3 0.1 2.8 0.5 0.5 1.7 4.6 1.0 1.3 0.5 8.4 0.5 0.4 0.0 1.9 0.0 0.3 0.9 0.6 0.0 0.0 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.1 0.0 0.0 0.0 0.0 1.7 0.8 0.3 0.1 0.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 18.5 0.0 2.7 0.0 0.0 0.0 0.0 0.9 15.8 0.5 0.2 0.1 0.0 0.0 0.1 13.1 0.0 0.3 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 10.1 0.5 36.6 2.8 27.1 3.1 14.0 7.5 0.4 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 35.0;thyroid gland: 79.5" "Group enriched" "Detected in some" 5 "AF22: 35.8;SCLC-21H: 9.4" "Group enriched" "Detected in many" 6 "pancreatic cancer: 14.6;thyroid cancer: 65.1" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 22 "basophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" Vesicles "HPA049627: " "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 1.6 35.0 16.3 1.7 20.5 1.3 1.3 7.7 27.8 2.9 4.2 1.6 0.0 6.2 0.9 1.2 2.1 2.0 1.4 3.1 18.0 11.1 1.1 1.0 2.2 0.8 4.1 16.2 11.6 23.7 0.9 1.7 1.5 9.0 1.3 2.8 16.6 2.7 2.3 1.0 16.6 3.3 1.3 5.4 0.9 11.9 4.7 3.8 0.0 79.5 0.0 0.9 1.9 1.8 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 20.5 7.7 27.8 18.0 11.1 4.1 16.2 9.0 3.8 PCSK4 "DKFZp434B217, MGC34749, PC4, SPC5" ENSG00000115257 "Proprotein convertase subtilisin/kexin type 4" Q6UW60 19 1481428-1490752 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 50.7" "Cell line enhanced" "Detected in some" "AN3-CA: 9.9;HMC-1: 5.3;U-266/70: 10.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 1.2;plasmacytoid DC: 1.7" "Group enriched" "Detected in many" 4 "dendritic cells: 1.7;T-cells: 1.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA005572 Uncertain "HPA005572: AB_1855087" "unprognostic (1.00e-2)" "unprognostic (9.12e-2)" "unprognostic (2.36e-3)" "prognostic favourable (9.45e-5)" "unprognostic (5.23e-2)" "unprognostic (6.14e-2)" "unprognostic (1.78e-1)" "unprognostic (6.34e-3)" "unprognostic (2.94e-1)" "unprognostic (8.29e-3)" "unprognostic (1.93e-2)" "unprognostic (7.44e-2)" "unprognostic (6.56e-2)" "unprognostic (3.82e-2)" "unprognostic (1.71e-2)" "unprognostic (3.57e-2)" "unprognostic (7.03e-2)" 0.5 1.2 2.5 0.6 3.4 0.9 0.7 0.6 1.8 1.2 0.9 1.8 2.5 2.5 0.8 2.2 0.7 4.2 1.0 0.4 2.5 2.1 1.7 2.0 0.8 0.6 1.0 2.0 0.8 3.8 1.4 4.2 0.5 2.3 1.2 0.4 2.4 1.3 2.4 0.5 0.8 1.1 0.6 1.2 0.7 1.2 50.7 1.8 1.2 2.0 0.0 0.4 0.7 0.6 0.0 1.7 0.0 0.3 0.0 1.2 0.1 0.8 0.5 1.7 9.9 0.2 0.3 2.6 0.7 0.2 0.1 0.3 0.9 1.4 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.6 0.2 0.4 1.4 1.3 0.7 0.0 5.3 0.8 0.0 0.0 0.1 0.2 1.6 2.5 0.0 0.0 0.2 0.4 0.1 0.5 1.7 0.1 0.2 0.6 0.0 0.0 2.0 0.2 0.4 0.1 3.6 0.5 0.0 0.8 0.1 0.2 0.0 10.9 1.9 0.3 0.5 0.9 0.4 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.2 0.0 0.0 1.2 0.1 0.0 0.0 0.0 1.7 0.0 0.1 2.5 3.4 0.6 1.8 2.5 2.1 1.0 2.0 2.3 1.8 PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362339 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "blood: 157.6;intestine: 71.5" "Cell line enhanced" "Detected in many" "BEWO: 15.5;HaCaT: 21.8;RH-30: 14.4;RPTEC TERT1: 20.2;U-2 OS: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 157.6;neutrophil: 57.4" "Lineage enriched" "Detected in all" 12 "granulocytes: 157.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" "Golgi apparatus" "HPA031072: AB_10602190" "unprognostic (3.28e-2)" "unprognostic (1.44e-1)" "unprognostic (4.13e-4)" "unprognostic (4.08e-2)" "unprognostic (7.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-3)" "unprognostic (9.39e-2)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (2.81e-2)" "unprognostic (6.80e-2)" "prognostic unfavourable (9.61e-5)" "unprognostic (2.99e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-5)" 15.8 3.8 2.9 13.7 2.8 1.5 9.5 2.4 3.2 8.5 51.8 2.9 4.5 19.7 6.5 13.9 9.6 7.8 22.9 6.7 3.8 2.4 3.7 1.9 7.7 5.6 2.3 3.1 17.2 3.4 9.5 3.2 7.7 3.5 4.5 6.7 3.3 5.0 5.8 4.0 4.8 71.5 6.9 3.5 2.5 3.3 5.1 2.4 18.0 6.4 14.2 4.5 7.1 11.4 11.7 12.2 157.6 4.4 12.6 12.7 0.8 1.1 0.8 2.4 1.6 1.5 0.5 15.5 2.1 0.2 0.1 0.0 8.2 0.9 0.3 0.6 0.2 21.8 1.1 0.6 0.1 0.2 1.9 2.8 1.6 0.7 0.4 0.8 1.3 2.9 0.2 0.5 0.2 4.5 3.2 1.0 1.5 5.1 3.2 4.9 10.6 0.9 0.6 14.4 0.8 20.2 1.2 0.2 0.2 3.3 0.7 0.2 1.2 3.5 3.5 0.7 31.5 1.8 0.9 0.2 0.1 0.4 2.4 1.2 12.0 157.6 4.2 16.2 9.7 2.3 8.3 8.8 9.8 8.9 1.9 11.7 9.9 12.7 57.4 12.6 4.4 12.2 8.4 0.8 2.9 2.8 2.4 3.2 3.8 2.4 2.3 3.1 3.5 2.4 PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101297142-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.3;liver: 76.0;lymphoid tissue: 37.4" "Cell line enhanced" "Detected in many" "BEWO: 26.1;CACO-2: 18.3;HEK 293: 27.5;Hep G2: 24.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 7.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" 38000 "HPA004774: AB_1079583" "prognostic favourable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavourable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" 3.0 1.5 5.1 1.5 25.1 0.9 6.1 4.5 11.5 1.5 8.4 41.9 0.0 3.6 1.4 2.5 4.8 1.9 1.9 10.1 8.9 5.7 1.7 76.0 2.3 4.6 38.8 8.4 4.0 1.7 0.5 3.1 16.5 29.0 1.9 8.2 0.7 1.5 0.7 3.5 4.0 4.8 1.9 69.3 37.4 5.3 6.6 24.5 3.7 1.4 3.5 1.3 1.6 1.6 2.6 0.7 1.9 2.4 7.5 1.4 2.5 8.6 7.0 1.3 0.9 0.1 0.1 26.1 0.5 1.3 0.0 0.1 18.3 4.0 0.2 1.2 0.2 5.9 7.0 0.7 0.1 1.2 27.5 15.0 3.6 24.6 0.8 2.1 0.3 0.4 4.8 0.1 0.2 0.0 11.5 0.2 0.0 4.2 0.1 1.9 3.7 3.0 0.2 0.2 1.9 2.3 12.2 3.5 3.8 12.1 0.9 3.9 1.0 9.5 0.1 0.1 0.7 0.2 0.0 0.3 0.3 0.3 0.1 0.3 3.4 1.3 0.6 1.9 0.6 0.8 0.7 1.1 1.0 0.5 0.2 2.6 1.4 1.3 1.1 7.5 2.4 0.7 0.2 2.5 5.1 25.1 4.5 10.4 8.9 5.7 38.8 8.4 29.0 24.5 PCYOX1 "KIAA0908, PCL1" ENSG00000116005 "Prenylcysteine oxidase 1" Q9UHG3 2 70257386-70281191 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035193 Approved "Intracellular and membrane" 480000000 "HPA035193: AB_10602017" "unprognostic (1.09e-1)" "unprognostic (1.72e-2)" "unprognostic (7.91e-2)" "unprognostic (1.15e-2)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (6.87e-2)" "unprognostic (6.28e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (1.61e-1)" "unprognostic (4.38e-2)" "prognostic favourable (1.89e-4)" "unprognostic (3.26e-2)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" 36.6 20.6 12.9 13.5 17.0 2.1 21.7 12.5 19.7 32.2 20.1 13.2 27.2 12.9 31.3 26.5 24.5 23.0 26.5 22.5 12.3 24.1 48.9 53.3 29.2 10.6 14.9 17.4 22.1 12.9 47.7 29.8 18.8 23.2 24.2 12.8 30.5 55.8 31.4 42.0 17.2 18.3 24.6 13.8 10.8 17.3 11.3 10.8 5.0 31.8 22.8 13.7 24.5 23.1 4.6 8.4 13.5 7.2 6.6 13.4 6.8 9.1 13.2 10.6 11.8 78.9 40.7 9.3 15.6 14.4 8.7 6.6 20.6 8.1 0.9 6.7 21.3 15.0 7.7 12.1 10.0 5.2 6.5 3.5 10.3 17.9 7.9 3.3 3.1 39.0 13.4 11.6 3.3 10.3 6.2 6.7 12.3 5.5 2.4 5.3 6.4 5.6 4.6 22.2 8.1 12.4 10.2 2.7 5.9 23.5 11.6 10.9 9.5 4.3 12.8 14.7 8.2 12.9 8.1 5.6 12.5 1.1 17.7 4.6 5.3 13.5 7.2 7.4 10.0 6.3 12.5 4.6 9.8 8.1 6.7 3.7 13.4 11.2 5.0 6.6 6.4 8.4 8.6 6.8 12.9 17.0 12.5 19.7 12.3 24.1 14.9 17.4 23.2 10.8 PCYT1A "CT, CTPCT, PCYT1" ENSG00000161217 "Phosphate cytidylyltransferase 1, choline, alpha" P49585 3 196214222-196287957 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Cone-rod dystrophy, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035428 Approved Approved Nucleoplasm Nucleoplasm "HPA035428: AB_10602045" "unprognostic (8.58e-3)" "unprognostic (2.63e-1)" "unprognostic (8.45e-2)" "unprognostic (8.61e-3)" "unprognostic (2.87e-1)" "unprognostic (1.85e-1)" "prognostic unfavourable (8.65e-5)" "unprognostic (8.52e-2)" "unprognostic (5.99e-2)" "unprognostic (1.65e-2)" "unprognostic (6.72e-3)" "unprognostic (1.74e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (7.16e-3)" "unprognostic (2.41e-2)" 24.8 22.2 15.3 19.9 18.7 25.8 18.0 14.2 17.8 13.6 25.3 23.0 21.1 41.1 18.2 18.7 25.2 15.0 19.8 36.0 14.8 13.8 20.2 17.8 18.7 15.6 16.6 14.1 15.6 13.9 16.0 12.1 14.2 20.5 13.3 16.5 14.4 17.1 19.2 45.8 32.8 37.2 19.5 18.3 23.4 18.1 19.4 18.6 13.2 14.8 28.0 19.0 17.6 16.7 7.8 8.7 20.5 9.8 7.9 13.5 4.6 28.2 11.4 8.0 11.7 16.4 18.3 12.1 21.6 15.4 18.6 16.4 27.8 10.3 7.2 72.5 24.7 22.1 12.7 16.6 15.9 13.2 8.9 20.8 12.0 11.8 14.7 10.0 17.9 15.4 12.7 18.0 12.9 19.9 11.6 16.2 18.5 23.8 6.2 5.3 6.9 17.0 10.4 10.2 11.6 11.4 15.9 7.8 5.8 14.6 25.3 14.0 37.1 12.5 29.6 14.8 8.2 20.1 29.2 15.0 28.6 13.4 22.7 14.0 18.6 7.5 8.7 9.2 9.6 9.2 8.0 7.8 7.2 10.2 8.7 5.7 4.6 6.8 20.5 7.9 9.8 5.6 13.5 4.6 15.3 18.7 14.2 17.8 14.8 13.8 16.6 14.1 20.5 18.6 PCYT1B "CCT-beta, CTB" ENSG00000102230 "Phosphate cytidylyltransferase 1, choline, beta" Q9Y5K3 X 24558087-24672677 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;testis: 15.6" "Cell line enhanced" "Detected in some" "AF22: 8.2;CACO-2: 17.6;HEL: 21.6;Hep G2: 9.0;NTERA-2: 9.3;SCLC-21H: 6.4" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 2.7;neutrophil: 2.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006367 Uncertain "HPA006367: AB_1079585" "unprognostic (4.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.16e-1)" "unprognostic (7.39e-2)" "unprognostic (9.88e-2)" "unprognostic (6.83e-2)" "unprognostic (5.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (5.64e-2)" "unprognostic (2.63e-6)" "unprognostic (2.62e-4)" "unprognostic (4.56e-2)" "unprognostic (1.75e-2)" "unprognostic (1.96e-4)" 0.8 1.1 12.0 1.1 11.4 2.0 1.0 3.1 23.9 1.6 1.1 13.7 2.3 1.3 3.2 1.7 2.8 5.7 1.7 4.2 10.0 6.0 1.0 0.6 2.1 0.6 7.8 10.5 4.0 3.1 0.7 1.4 3.6 10.7 2.3 1.3 2.1 1.0 6.4 0.7 0.7 1.1 6.1 10.3 1.0 0.9 15.6 8.7 0.0 0.6 0.0 0.7 0.9 0.4 0.4 0.5 2.7 0.5 0.6 0.2 1.4 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 17.6 0.0 0.0 4.6 0.0 0.9 3.8 0.0 0.0 0.0 0.1 21.6 0.0 9.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.5 9.3 0.0 0.0 1.1 0.0 0.0 0.0 6.4 5.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 4.2 0.6 0.2 2.7 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.4 0.2 0.2 2.2 0.6 0.5 0.5 0.2 1.4 12.0 11.4 3.1 11.3 10.0 6.0 7.8 10.5 10.7 8.7 PCYT2 ET ENSG00000185813 "Phosphate cytidylyltransferase 2, ethanolamine" Q99447 17 81900965-81911464 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 70.8" "Cell line enhanced" "Detected in all" "Hep G2: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023033, HPA023034" Enhanced Supported "Intermediate filaments,Centrosome" 7000 Centrosome "Intermediate filaments" "HPA023033: AB_1855094, HPA023034: AB_1855095" "unprognostic (4.05e-3)" "unprognostic (4.39e-3)" "unprognostic (3.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (9.86e-2)" "unprognostic (1.24e-2)" "unprognostic (1.06e-1)" "unprognostic (4.24e-1)" "unprognostic (8.97e-3)" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "prognostic favourable (4.29e-6)" "unprognostic (1.19e-1)" "unprognostic (8.59e-2)" "unprognostic (1.63e-1)" "unprognostic (4.47e-2)" 13.6 5.5 13.3 5.7 12.7 5.3 10.4 12.2 17.0 6.5 16.2 13.4 6.4 30.7 5.8 8.6 7.6 12.2 8.0 17.7 14.0 11.8 21.7 46.5 7.2 6.3 13.4 16.0 7.8 11.5 8.2 4.6 6.0 15.9 10.1 8.5 5.8 10.8 6.6 13.5 4.5 26.5 5.0 14.3 4.1 11.5 70.8 11.0 5.6 6.7 6.8 5.8 7.5 4.4 7.3 6.6 2.1 3.5 4.7 8.4 4.0 12.1 7.0 5.6 15.8 28.2 14.9 8.3 8.7 18.8 12.3 14.6 27.4 12.7 4.2 4.8 9.1 10.0 8.5 16.2 7.1 1.2 6.9 9.2 9.6 62.6 30.2 9.2 7.7 12.2 9.4 11.1 8.6 11.3 17.0 8.8 9.1 10.3 10.9 11.4 4.5 7.5 7.2 6.0 15.0 14.7 23.0 7.2 6.6 6.6 36.4 8.5 10.1 21.9 7.6 9.1 6.0 6.8 7.2 5.7 2.4 4.1 9.4 12.4 8.9 2.1 3.5 1.2 7.1 3.4 4.6 6.0 8.4 7.2 6.6 7.3 7.0 7.2 1.0 4.7 3.0 6.5 5.0 4.0 13.3 12.7 12.2 17.0 14.0 11.8 13.4 16.0 15.9 11.0 PDE10A ENSG00000112541 "Phosphodiesterase 10A" Q9Y233 6 165327287-165986603 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.8" "Cell line enhanced" "Detected in some" "LHCN-M2: 13.7;RH-30: 8.0;RT4: 8.4;SH-SY5Y: 8.4;TIME: 14.2;U-2 OS: 7.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 36.8" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 11 "basal ganglia: 307.0" "Group enriched" "Detected in all" 4 "basal ganglia: 155.2;cerebellum: 80.7" "CAB045998, HPA047200" Supported "CAB045998: AB_2162589, HPA047200: " "unprognostic (1.02e-1)" "unprognostic (3.63e-2)" "unprognostic (3.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (6.03e-2)" "unprognostic (3.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavourable (4.44e-7)" "unprognostic (3.59e-3)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (5.90e-3)" 3.1 1.9 1.7 1.0 36.8 0.0 3.4 4.5 6.9 2.2 1.0 1.1 4.3 0.8 2.9 7.5 0.7 3.1 3.2 3.6 2.6 2.1 8.8 0.9 4.3 1.4 2.7 1.1 3.4 0.8 1.2 2.5 5.3 1.7 2.6 0.5 0.6 0.7 4.9 0.9 0.6 0.8 4.3 1.1 2.5 1.2 8.7 16.0 0.0 12.2 1.0 0.8 7.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.7 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.3 0.0 7.6 0.0 0.5 0.0 0.0 0.1 0.0 0.6 0.0 7.4 0.0 0.0 13.7 0.1 1.1 0.0 1.5 5.5 1.7 8.0 0.0 7.2 8.4 2.2 8.4 0.0 0.0 0.4 0.0 0.0 14.2 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 36.8 4.5 6.9 2.6 2.1 2.7 1.1 1.7 16.0 PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623252-178072755 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 20.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.7;fHDF/TERT166: 5.5;HAP1: 3.1;Hep G2: 6.2" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA034560 Approved "Intracellular and membrane" "HPA034560: AB_10602140" "unprognostic (1.02e-1)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.61e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.91e-1)" "unprognostic (9.95e-2)" "unprognostic (2.80e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-4)" "unprognostic (1.64e-3)" 2.9 0.5 1.3 0.7 1.0 0.2 2.5 0.2 0.8 4.2 3.1 0.1 0.0 1.2 1.9 1.5 0.3 0.4 5.4 2.6 1.6 2.0 4.0 11.8 0.5 0.0 3.3 0.0 0.5 7.8 9.8 13.6 0.0 1.2 20.8 0.5 5.6 8.5 1.2 7.5 0.3 7.6 1.7 5.6 0.1 0.4 3.8 0.0 0.1 13.2 0.7 0.1 0.6 0.3 1.0 0.8 2.2 0.9 0.9 0.7 0.2 0.1 1.0 0.5 0.2 0.2 0.0 0.2 2.5 0.4 0.1 0.8 0.5 3.7 0.1 1.5 5.5 0.2 3.1 0.1 0.1 0.0 2.0 2.4 0.2 6.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.9 0.3 1.2 0.1 0.5 0.1 0.5 0.0 1.1 0.1 0.7 1.7 0.0 0.2 0.4 0.3 0.0 0.0 0.3 0.6 0.2 0.3 0.5 0.0 0.0 1.0 0.1 0.2 1.6 0.7 1.1 0.7 0.6 0.5 0.7 0.6 0.7 0.4 1.0 0.6 0.7 2.2 0.9 0.9 0.8 0.7 0.2 1.3 1.0 0.2 0.7 1.6 2.0 3.3 0.0 1.2 0.0 PDE12 "2'-PDE, 3635, DKFZp667B1218" ENSG00000174840 "Phosphodiesterase 12" Q6L8Q7 3 57556276-57566844 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043171 Approved "HPA043171: AB_10794654" "unprognostic (2.79e-1)" "unprognostic (3.18e-1)" "prognostic favourable (2.85e-5)" "unprognostic (2.39e-1)" "unprognostic (1.48e-1)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (8.43e-3)" "unprognostic (1.27e-1)" "unprognostic (6.45e-2)" "unprognostic (2.10e-1)" "unprognostic (9.88e-3)" "prognostic favourable (3.63e-8)" "unprognostic (6.97e-3)" "unprognostic (1.32e-1)" "unprognostic (7.85e-2)" "unprognostic (2.62e-1)" 14.2 22.1 10.0 13.7 15.7 21.1 11.2 18.0 18.4 10.7 12.4 16.9 10.6 15.7 14.9 8.5 19.8 10.9 12.7 11.2 11.0 10.8 16.8 22.1 11.4 14.3 15.5 10.6 15.7 17.0 18.2 15.5 12.7 13.6 11.8 12.2 13.2 14.6 12.4 19.1 11.4 13.8 12.2 12.4 12.6 13.8 9.9 14.2 21.7 13.0 11.7 16.4 14.1 11.6 10.4 10.1 16.6 12.6 14.5 13.4 9.5 12.9 12.8 8.0 14.9 10.4 7.4 14.6 11.0 10.6 12.4 11.1 16.9 8.8 21.3 4.4 9.9 8.6 17.0 11.5 10.3 9.7 8.9 16.0 11.2 12.8 11.8 20.7 16.6 10.1 7.9 15.0 13.3 10.7 13.2 15.7 11.2 10.0 18.4 6.8 12.4 22.1 7.0 6.5 15.7 10.0 15.1 7.1 11.5 11.9 14.0 11.8 10.6 12.0 13.1 10.4 9.9 19.7 17.7 15.4 22.3 18.7 12.2 16.3 15.3 16.6 9.1 8.2 11.6 12.6 12.9 7.2 10.9 11.9 10.1 10.4 13.4 13.4 2.6 14.5 12.5 5.4 12.9 9.5 10.0 15.7 18.0 18.4 11.0 10.8 15.5 10.6 13.6 14.2 PDE1A ENSG00000115252 "Phosphodiesterase 1A" P54750 2 182140036-182523192 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 66.0;kidney: 37.1" "Group enriched" "Detected in some" 5 "ASC diff: 22.3;HHSteC: 13.2;HSkMC: 28.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 1.4" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 6 "amygdala: 118.0;basal ganglia: 76.2;cerebral cortex: 161.5;hippocampal formation: 155.8;hypothalamus: 47.8" "Low region specificity" "Detected in many" HPA022151 Approved Approved Nucleoplasm Nucleoplasm "HPA022151: AB_1855118" "unprognostic (3.63e-1)" "unprognostic (7.21e-2)" "unprognostic (1.32e-1)" "unprognostic (8.61e-2)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (3.84e-1)" "unprognostic (3.82e-1)" "unprognostic (1.02e-1)" "unprognostic (5.38e-2)" "unprognostic (2.78e-1)" "unprognostic (2.86e-1)" "unprognostic (5.55e-3)" "unprognostic (2.50e-3)" "unprognostic (5.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.40e-3)" 7.6 3.9 13.8 3.6 11.5 0.5 4.1 66.0 25.3 11.5 8.8 6.2 1.7 2.6 7.3 6.7 4.7 7.4 18.2 11.8 12.6 4.1 37.1 3.2 3.1 1.8 7.1 15.7 9.2 2.0 1.3 2.3 1.3 6.9 3.8 5.6 3.0 1.8 4.8 2.4 2.1 4.6 11.8 10.1 2.6 4.6 24.6 9.0 0.0 35.1 2.6 1.1 8.3 9.0 0.0 1.4 0.8 0.2 0.0 0.0 0.0 0.0 0.1 2.2 0.0 22.3 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 0.0 3.1 0.0 13.2 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 4.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 3.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 13.8 11.5 66.0 25.3 12.6 4.1 7.1 15.7 6.9 9.0 PDE1B PDES1B ENSG00000123360 "Phosphodiesterase 1B" Q01064 12 54549350-54579239 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 52.6" "Cell line enhanced" "Detected in some" "HDLM-2: 11.3;HL-60: 6.3;HMC-1: 12.1;NB-4: 8.0;THP-1: 7.7;U-937: 6.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 52.6" "Cell type enriched" "Detected in single" 4 "naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 4 "T-cells: 1.6" "Region enriched" "Detected in all" 6 "basal ganglia: 895.2" "Region enriched" "Detected in all" 7 "basal ganglia: 253.8" HPA018492 Enhanced "HPA018492: AB_1855119" "unprognostic (2.90e-1)" "unprognostic (1.51e-1)" "unprognostic (7.67e-4)" "unprognostic (5.63e-3)" "unprognostic (7.02e-2)" "unprognostic (7.51e-2)" "unprognostic (1.97e-1)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "unprognostic (5.11e-2)" "unprognostic (3.84e-3)" "unprognostic (2.70e-2)" "prognostic unfavourable (4.77e-6)" "unprognostic (6.64e-4)" "unprognostic (2.14e-1)" "unprognostic (3.09e-1)" "unprognostic (2.83e-2)" 12.3 1.4 9.9 4.6 52.6 5.6 2.7 3.1 19.4 2.6 3.7 1.4 0.0 1.2 3.9 2.5 1.7 2.4 2.9 1.9 3.7 3.8 1.3 1.6 2.9 1.6 3.0 9.3 12.5 0.6 11.0 0.5 0.5 5.8 1.0 1.7 0.5 1.3 2.1 0.7 1.0 2.6 4.9 1.2 4.8 2.5 1.1 7.7 0.0 2.7 0.0 1.1 2.8 1.1 0.2 0.3 0.1 0.3 0.1 1.6 0.4 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.1 0.0 0.0 1.8 0.0 0.0 11.3 0.3 4.6 0.0 0.0 0.0 6.3 12.1 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.7 8.0 3.3 0.0 2.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.4 0.0 6.4 1.2 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.2 1.6 0.0 0.1 0.1 0.0 0.0 0.0 0.4 9.9 52.6 3.1 19.4 3.7 3.8 3.0 9.3 5.8 7.7 PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32299329 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease mutation, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.6;heart muscle: 56.2" "Cell line enhanced" "Detected in some" "BJ: 15.0;fHDF/TERT166: 48.3;U-251 MG: 26.1;WM-115: 34.5" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm Nucleoplasm "HPA052375: " "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" 2.9 2.7 10.6 3.2 27.7 0.9 5.1 2.4 17.1 1.2 2.7 30.1 0.0 2.3 3.1 6.8 7.4 8.4 2.4 56.2 14.8 7.5 4.0 1.0 5.0 1.4 31.1 12.0 4.9 2.7 1.3 1.3 4.0 16.3 2.9 2.7 7.9 2.6 4.2 1.4 0.9 2.8 10.4 17.1 1.4 3.8 4.2 33.6 0.0 3.9 0.2 1.0 7.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 5.2 0.0 0.2 0.1 0.0 15.0 6.1 7.1 5.8 0.0 0.0 0.0 0.0 48.3 0.4 0.0 0.0 9.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 10.8 0.6 0.0 1.4 0.0 2.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 7.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 2.9 0.1 26.1 0.0 0.0 0.0 0.7 0.1 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 27.7 2.4 17.1 14.8 7.5 31.1 12.0 16.3 33.6 PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.0;lymphoid tissue: 65.4" "Cell line enriched" "Detected in some" 8 "HeLa: 105.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 30.4;basal ganglia: 34.2;cerebral cortex: 48.0;hippocampal formation: 18.0;olfactory region: 27.0" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.7;T-cells: 9.6" "Group enriched" "Detected in many" 5 "amygdala: 111.5;basal ganglia: 166.3;cerebral cortex: 98.9;hippocampal formation: 120.9" "CAB009752, HPA031192" Enhanced Supported Cytosol Cytosol "CAB009752: AB_2268159, HPA031192: " "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favourable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" 27.8 18.4 30.4 3.0 34.2 2.5 25.4 1.0 48.0 8.9 7.7 3.8 1.9 3.5 9.4 4.9 10.2 11.6 12.0 11.3 18.0 6.1 7.0 10.4 5.1 3.8 3.8 27.0 3.4 2.4 4.4 3.4 6.6 6.7 4.8 5.2 3.0 2.3 6.3 6.6 4.8 4.2 10.3 2.1 65.4 4.2 2.9 7.4 0.1 7.0 3.9 2.2 8.3 11.2 3.7 1.2 0.2 1.0 0.1 9.6 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 2.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 105.0 0.1 0.2 0.0 1.6 0.0 0.2 0.5 4.3 2.3 0.1 0.1 0.0 0.0 0.0 0.0 1.5 2.9 0.0 0.0 0.2 0.0 0.0 9.4 0.5 0.0 0.0 0.4 0.0 0.0 13.4 0.0 2.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.8 0.0 9.6 1.0 5.6 3.7 5.7 5.6 1.2 2.5 3.7 3.0 0.2 0.1 0.5 0.0 2.3 1.9 30.4 34.2 1.0 48.0 18.0 6.1 3.8 27.0 6.7 7.4 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20369245-20684381 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.2" "Cell line enhanced" "Detected in some" "AF22: 7.7;HEL: 14.2;HeLa: 38.7;HUVEC TERT2: 6.9;SH-SY5Y: 14.5;U-138 MG: 11.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 35.4" "HPA014492, HPA074258" Uncertain Approved "Plasma membrane" 23000 "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavourable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 7.1 1.0 1.7 4.7 2.0 0.0 3.8 3.5 1.4 7.8 15.9 1.0 2.0 2.1 7.8 3.5 9.1 4.9 5.5 62.2 1.6 1.4 3.7 1.8 3.9 3.3 1.9 1.1 7.1 6.5 1.0 2.8 13.8 2.7 6.3 9.0 12.0 7.8 4.2 2.0 1.4 21.4 6.0 1.8 2.1 5.5 2.3 0.7 0.0 2.8 1.9 0.9 4.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 7.7 0.0 1.8 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.2 38.7 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.1 0.0 0.0 0.0 2.1 0.0 0.1 14.5 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.7 2.0 3.5 1.4 1.6 1.4 1.9 1.1 2.7 0.7 PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643723-14872044 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 42.6" "Cell line enhanced" "Detected in many" "HL-60: 13.3;Karpas-707: 15.4;THP-1: 16.3;U-266/70: 17.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 19.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 5.0;T-cells: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA056111: " "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.76e-3)" "unprognostic (4.25e-1)" "unprognostic (1.84e-3)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "prognostic favourable (7.91e-4)" "unprognostic (1.77e-1)" "unprognostic (2.33e-2)" "unprognostic (1.39e-2)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-3)" 42.6 1.0 2.3 12.6 2.2 6.7 17.0 19.2 3.0 2.9 21.8 0.9 0.8 2.2 0.9 1.4 2.6 1.0 6.9 4.7 2.2 2.1 2.4 18.2 10.2 14.1 1.6 1.6 0.9 7.3 0.3 5.1 5.5 1.5 10.7 8.1 1.9 16.5 1.3 0.8 0.9 6.3 9.7 2.1 8.7 3.0 12.5 0.8 7.8 1.2 2.3 7.1 10.5 4.5 0.3 0.4 5.0 1.2 0.1 8.7 1.8 0.0 1.5 3.3 5.4 6.6 0.0 1.3 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.1 11.1 0.1 8.1 10.0 2.3 13.3 0.0 0.5 0.0 0.0 0.3 0.0 11.7 15.4 0.0 0.1 2.6 6.5 4.5 2.4 6.4 1.5 10.0 0.0 1.1 5.1 9.5 1.3 8.6 2.9 0.0 16.3 0.0 0.0 0.8 0.0 0.0 17.4 5.3 0.4 0.1 2.3 1.0 0.0 0.7 2.9 1.4 0.7 2.9 0.3 4.2 3.2 0.4 0.2 8.7 7.5 5.0 0.1 1.2 0.1 4.2 1.8 2.3 2.2 19.2 3.0 2.2 2.1 1.6 1.6 1.5 0.8 PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469631 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5;testis: 31.8" "Cell line enhanced" "Detected in many" "HMC-1: 21.6;NB-4: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Plasma membrane" "Plasma membrane" "CAB017632: AB_1127109, HPA043310: , HPA076091: " "unprognostic (1.29e-2)" "unprognostic (3.98e-2)" "unprognostic (8.91e-2)" "unprognostic (1.82e-1)" "unprognostic (7.00e-2)" "unprognostic (6.84e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-2)" "unprognostic (6.90e-2)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (1.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.15e-1)" 6.4 2.5 9.0 4.2 13.9 3.4 6.3 15.0 38.5 8.4 4.3 3.2 0.4 2.0 4.4 1.1 3.1 4.8 5.0 4.1 12.4 6.9 2.8 1.9 7.7 2.0 5.3 19.4 1.7 9.8 17.3 2.3 4.9 34.7 3.7 3.0 3.1 7.1 4.0 26.1 2.2 2.7 4.7 3.6 4.1 6.1 31.8 4.5 0.0 5.4 1.0 1.9 4.6 3.5 0.2 3.3 5.9 4.4 5.3 2.0 1.3 0.0 1.4 0.3 3.9 11.4 6.8 2.2 3.2 6.5 0.4 1.1 3.4 3.1 1.4 9.6 8.4 0.3 2.2 0.4 0.2 3.7 3.2 13.4 4.7 3.7 7.4 2.2 21.6 5.0 0.4 3.6 0.0 3.1 10.5 3.2 2.3 0.9 1.3 24.9 1.7 2.8 8.8 2.2 11.5 0.5 0.8 2.5 0.9 0.2 0.1 3.5 0.5 4.4 6.5 4.9 6.3 3.3 2.0 6.4 0.5 7.1 2.1 0.1 3.9 5.9 2.6 5.1 1.5 4.4 0.8 0.2 0.5 2.0 3.3 0.1 0.1 0.7 0.2 5.3 4.4 0.2 1.2 1.3 9.0 13.9 15.0 38.5 12.4 6.9 5.3 19.4 34.7 4.5 PDE4B DPDE4 ENSG00000184588 "Phosphodiesterase 4B" Q07343 1 65792514-66374579 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.2" "Cell line enhanced" "Detected in many" "AN3-CA: 23.9;HUVEC TERT2: 35.9;NTERA-2: 21.8;SK-MEL-30: 21.6;TIME: 20.0;U-266/84: 18.8" "Cancer enhanced" "Detected in all" "glioma: 18.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 36.6" "Group enriched" "Detected in all" 5 "B-cells: 16.1;granulocytes: 36.6;T-cells: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003005 Uncertain Approved "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA003005: AB_1079587" "unprognostic (7.86e-2)" "unprognostic (3.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.90e-1)" "unprognostic (3.21e-1)" "unprognostic (3.33e-3)" "unprognostic (1.35e-1)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (6.10e-2)" "unprognostic (8.78e-2)" "unprognostic (4.24e-2)" "prognostic unfavourable (5.04e-4)" "unprognostic (2.89e-2)" "unprognostic (3.54e-1)" "unprognostic (9.04e-3)" "unprognostic (8.33e-3)" 14.9 2.9 21.5 28.4 29.0 48.2 15.0 12.7 31.9 6.4 6.6 39.2 0.7 3.9 6.7 2.1 3.9 3.5 8.1 16.1 20.7 18.8 3.7 8.7 10.0 15.9 36.3 14.2 2.0 1.7 1.7 3.4 13.1 32.2 18.3 8.6 6.6 15.9 10.3 28.2 6.2 8.5 9.5 37.4 18.5 4.2 3.2 36.9 2.3 5.5 5.5 14.7 16.1 3.9 16.1 2.6 36.6 2.8 4.4 13.3 3.7 0.0 6.8 13.5 23.9 0.7 0.7 0.0 4.4 5.2 4.2 5.5 0.0 0.0 2.0 0.1 8.2 0.0 0.1 0.0 4.1 5.8 0.0 0.1 1.9 0.0 0.5 4.8 0.0 1.4 0.2 2.1 0.1 35.9 0.0 1.3 1.8 0.1 0.0 2.8 21.8 0.3 0.9 2.4 1.3 3.3 0.0 0.1 10.4 0.0 1.1 21.6 0.1 1.7 20.0 3.3 0.8 1.8 0.7 0.6 18.8 7.3 3.4 5.0 1.4 2.7 2.8 8.4 4.4 2.4 8.4 15.4 8.3 6.2 2.4 16.1 9.4 6.5 36.6 4.4 2.1 2.6 13.3 3.7 21.5 29.0 12.7 24.6 20.7 18.8 36.3 14.2 32.2 36.9 PDE4C DPDE1 ENSG00000105650 "Phosphodiesterase 4C" Q08493 19 18208652-18248200 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 28.6" "Cell line enhanced" "Detected in some" "BEWO: 5.9;Hep G2: 3.9;U-87 MG: 8.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA048975 Approved "HPA048975: " "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (5.22e-4)" "unprognostic (1.44e-2)" "unprognostic (7.70e-2)" "unprognostic (1.15e-1)" "unprognostic (4.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-3)" "unprognostic (2.21e-1)" "unprognostic (7.25e-10)" "unprognostic (2.73e-2)" "unprognostic (2.65e-1)" "unprognostic (9.21e-2)" "unprognostic (2.45e-2)" 2.0 1.3 1.8 1.5 2.8 1.0 2.0 0.8 6.1 4.1 4.4 1.5 3.1 1.5 6.4 6.8 1.3 4.2 5.6 4.2 1.6 1.9 4.1 2.0 4.1 0.5 1.7 5.1 2.0 0.8 0.3 3.5 7.0 2.8 5.8 1.3 2.5 1.3 5.4 13.4 0.6 4.1 3.4 0.7 2.3 5.2 2.6 1.1 0.4 1.2 28.6 0.7 1.8 3.3 1.3 0.6 3.5 0.7 1.0 0.7 0.2 0.1 0.3 0.2 0.3 0.1 0.3 5.9 0.1 0.0 0.2 0.3 1.2 0.2 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.4 3.9 0.2 0.2 0.5 0.7 0.1 2.5 0.0 0.0 0.9 2.0 0.1 0.4 0.2 0.3 0.1 0.2 0.2 0.3 0.4 0.1 0.2 0.2 0.8 0.3 0.5 0.0 0.5 0.3 0.0 0.4 0.2 0.7 0.1 1.3 0.6 0.2 8.8 0.2 0.3 3.4 0.7 1.0 0.6 0.4 0.5 0.5 0.5 0.4 0.2 1.3 0.5 0.7 3.5 1.0 0.4 0.6 0.3 0.2 1.8 2.8 0.8 6.1 1.6 1.9 1.7 5.1 2.8 1.1 PDE4D DPDE3 ENSG00000113448 "Phosphodiesterase 4D" Q08499 5 58969038-60522120 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.0" "Cell line enhanced" "Detected in many" "A549: 24.8;AN3-CA: 28.5;HeLa: 41.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "eosinophil: 28.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045895 Approved Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA045895: AB_10960275" "unprognostic (1.14e-1)" "unprognostic (8.73e-3)" "unprognostic (4.35e-2)" "unprognostic (7.87e-2)" "unprognostic (5.97e-2)" "unprognostic (2.03e-1)" "unprognostic (8.10e-4)" "unprognostic (1.17e-1)" "unprognostic (6.59e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "prognostic favourable (4.00e-5)" "unprognostic (1.51e-1)" "unprognostic (8.20e-2)" "unprognostic (1.77e-2)" "unprognostic (2.56e-2)" 8.2 1.9 4.4 6.8 8.6 46.2 5.3 4.2 13.0 13.5 18.6 1.4 14.7 4.1 17.1 14.0 10.3 6.6 12.7 15.5 4.5 5.8 12.8 3.4 11.1 3.7 5.2 6.6 5.3 2.9 7.0 9.0 11.8 2.7 18.2 11.2 8.6 24.4 16.5 60.0 5.1 7.5 35.8 5.0 3.8 10.2 2.6 2.8 4.4 6.2 11.3 9.5 20.0 11.2 6.1 0.7 28.1 1.1 0.1 0.8 0.5 0.0 24.8 5.2 28.5 0.9 1.8 4.1 0.6 0.7 1.4 2.0 9.7 0.8 1.9 0.1 0.2 4.2 0.0 1.1 2.4 1.1 2.8 3.6 41.0 2.1 3.8 1.7 0.2 3.8 0.9 3.9 0.7 2.9 0.0 0.6 2.4 1.7 1.3 4.0 0.9 1.3 0.4 6.5 4.1 6.5 9.3 0.9 3.3 6.5 11.0 5.6 0.8 3.7 3.4 0.3 0.1 4.9 1.3 1.4 0.0 0.2 4.2 6.8 1.1 2.0 1.1 28.1 0.8 0.0 0.8 6.1 0.7 0.3 0.7 6.1 0.5 0.4 1.5 0.1 0.1 0.0 0.4 0.5 4.4 8.6 4.2 13.0 4.5 5.8 5.2 6.6 2.7 2.8 PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494395-119628991 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.3;HHSteC: 35.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved "Centriolar satellite,Cytosol" 3100000 Cytosol "Centriolar satellite" "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favourable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavourable (1.17e-4)" 12.3 4.9 2.0 28.2 2.3 0.4 8.1 3.0 2.3 21.3 28.0 1.7 20.1 6.5 17.3 21.4 30.7 10.7 13.3 5.3 2.0 2.8 3.8 1.2 11.4 4.1 2.4 3.4 10.0 7.8 5.1 3.4 8.9 4.4 31.8 11.7 20.2 8.5 23.7 6.8 4.2 15.6 45.6 2.0 2.1 9.1 7.6 1.2 0.9 9.1 8.1 2.2 25.9 15.9 1.5 0.5 1.4 0.4 0.6 2.1 4.2 8.0 0.4 5.7 0.6 1.9 2.9 1.0 5.4 24.3 0.2 0.5 0.5 0.7 0.8 0.2 6.7 2.9 1.8 0.8 0.7 0.2 3.7 9.0 1.4 0.4 35.0 1.9 0.9 3.2 1.7 0.6 0.0 0.7 1.0 1.5 0.8 0.4 2.4 0.3 1.2 1.4 0.3 2.9 2.1 2.1 2.4 2.2 4.5 6.3 7.9 0.6 1.4 1.0 1.2 3.2 2.8 1.7 0.7 2.1 1.0 0.7 3.1 0.5 0.4 0.0 0.3 0.0 0.6 0.1 2.1 1.5 1.3 0.4 0.2 1.0 0.6 0.9 1.4 0.6 0.4 0.5 0.4 4.2 2.0 2.3 3.0 2.3 2.0 2.8 2.4 3.4 4.4 1.2 PDE6A "PDEA, RP43" ENSG00000132915 "Phosphodiesterase 6A" P16499 5 149857955-149944793 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 153.4" "Cell line enriched" "Detected in some" 4 "CACO-2: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016970, HPA074677" Enhanced "HPA016970: AB_1855125, HPA074677: AB_2732264" "unprognostic (6.85e-2)" "unprognostic (8.84e-2)" "unprognostic (1.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (4.39e-3)" "unprognostic (8.83e-2)" "unprognostic (6.54e-2)" "unprognostic (5.91e-3)" "unprognostic (1.77e-2)" "unprognostic (9.21e-2)" "unprognostic (7.57e-5)" "unprognostic (9.93e-2)" "unprognostic (3.08e-1)" "unprognostic (1.31e-1)" "unprognostic (2.26e-2)" 0.2 2.3 0.2 0.2 0.2 0.9 0.2 0.3 0.2 0.2 1.8 0.2 0.3 0.2 0.2 20.1 2.4 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 4.6 0.2 0.2 0.2 1.0 153.4 1.4 0.2 0.2 1.6 0.2 0.2 0.2 0.2 0.1 3.1 0.2 0.2 0.4 0.3 0.5 0.2 0.2 1.5 0.8 3.3 0.8 1.2 0.8 0.1 0.4 0.7 0.6 0.5 0.3 0.3 0.6 0.3 0.1 0.4 0.1 7.4 0.8 0.9 1.3 0.2 0.7 0.2 0.4 0.5 0.6 0.3 1.0 1.1 0.6 0.2 0.7 0.6 0.3 1.1 0.9 0.6 0.2 0.3 1.4 1.4 0.3 0.4 0.9 0.5 0.5 0.3 0.8 0.7 0.5 0.9 0.8 1.1 0.0 0.7 0.2 1.0 0.5 1.4 0.8 1.6 0.8 0.5 0.6 0.3 0.5 0.8 0.8 0.6 3.3 0.8 0.5 0.6 0.4 0.5 0.7 0.6 0.5 0.2 1.5 0.7 0.8 2.8 1.2 0.5 0.8 0.4 0.1 0.2 0.2 0.3 0.2 0.2 0.0 0.2 0.2 0.2 0.2 PDE6B "CSNB3, CSNBAD2, PDEB, rd1, RP40" ENSG00000133256 "Phosphodiesterase 6B" P35913 4 625584-670782 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Congenital stationary night blindness, Disease mutation, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2;retina: 64.2" "Cell line enhanced" "Detected in some" "EFO-21: 8.0;MOLT-4: 20.5;REH: 11.1;SCLC-21H: 14.0;SH-SY5Y: 8.2;U-266/84: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054148, HPA059929" Enhanced Approved Cytosol Cytosol "HPA054148: , HPA059929: " "unprognostic (2.43e-2)" "unprognostic (1.33e-4)" "unprognostic (2.45e-4)" "unprognostic (7.18e-3)" "unprognostic (1.88e-2)" "unprognostic (5.04e-3)" "unprognostic (7.32e-3)" "prognostic favourable (5.34e-4)" "unprognostic (9.70e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.67e-2)" "unprognostic (2.26e-1)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" 1.6 1.9 12.1 4.6 19.1 6.7 3.8 2.3 13.2 2.3 1.3 30.2 1.5 0.8 2.5 3.9 1.4 9.6 3.2 5.2 18.1 10.2 4.6 0.7 4.2 12.0 29.6 9.8 2.6 1.4 9.1 3.2 2.6 14.5 2.5 1.0 64.2 3.5 2.9 0.7 1.8 2.2 2.1 20.2 8.7 2.5 3.6 22.4 4.3 11.4 0.2 8.3 4.1 1.1 16.5 14.1 11.2 5.8 10.2 13.1 7.1 0.0 0.2 0.8 0.4 0.2 0.3 0.2 0.0 0.0 0.5 1.4 0.0 0.1 0.2 8.0 0.2 0.1 1.7 0.4 0.0 0.1 0.0 0.6 0.2 0.0 4.1 0.1 0.3 0.5 0.1 2.4 0.0 0.7 0.1 0.6 0.0 0.2 20.5 0.2 6.5 0.2 11.1 0.2 0.4 1.4 0.9 14.0 8.2 0.0 0.3 0.1 0.4 0.0 0.2 0.1 0.8 0.1 0.3 5.4 15.2 0.2 0.2 0.2 0.1 11.2 4.2 0.6 11.5 5.8 10.5 10.0 7.7 7.9 6.6 16.5 12.2 13.1 1.1 10.2 5.6 14.1 11.4 7.1 12.1 19.1 2.3 10.0 18.1 10.2 29.6 9.8 14.5 22.4 PDE6G "PDEG, RP57" ENSG00000185527 "Phosphodiesterase 6G" P18545 17 81650459-81663112 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 260.3" "Cell line enhanced" "Detected in some" "Hep G2: 6.4;NB-4: 6.8;NTERA-2: 11.8;REH: 13.7" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 29.7;NK-cell: 57.8" "Group enriched" "Detected in all" 5 "granulocytes: 29.7;NK-cells: 57.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles Vesicles "HPA045118: " "unprognostic (6.16e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.51e-3)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "unprognostic (6.33e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (4.85e-2)" "unprognostic (5.01e-2)" "unprognostic (1.94e-2)" "unprognostic (5.71e-2)" "unprognostic (5.44e-2)" "unprognostic (2.73e-1)" "unprognostic (1.14e-1)" 0.9 1.3 0.4 2.9 0.5 4.7 0.7 0.5 0.6 0.4 0.8 0.5 0.4 0.0 0.4 0.5 0.6 0.3 1.6 0.5 0.5 0.7 3.8 2.6 2.0 13.8 0.6 0.5 0.5 0.4 0.0 0.5 8.6 0.5 0.5 0.5 260.3 0.5 0.4 0.6 0.8 2.8 0.4 0.8 17.9 0.7 2.2 0.5 2.5 0.6 0.4 4.6 2.1 0.4 1.3 8.6 29.7 7.7 57.8 2.4 3.7 0.2 0.3 0.5 0.0 0.3 0.0 0.0 0.3 1.2 1.2 1.3 0.1 0.8 0.6 0.2 0.7 0.1 0.2 0.2 2.9 0.2 0.0 0.9 0.1 6.4 1.0 0.1 0.2 0.0 0.2 1.2 0.0 3.3 0.1 0.3 1.3 0.8 0.1 6.8 11.8 0.4 13.7 0.1 2.1 0.0 0.0 0.1 0.3 0.0 0.3 0.5 0.1 0.8 1.3 0.4 0.1 0.2 0.3 0.1 0.6 1.0 1.6 2.7 0.2 29.7 5.1 8.6 1.2 7.7 0.4 0.8 0.3 0.6 8.6 1.3 0.7 2.4 0.7 57.8 4.2 0.8 0.0 3.7 0.4 0.5 0.5 0.6 0.5 0.7 0.6 0.5 0.5 0.5 PDE6H ENSG00000139053 "Phosphodiesterase 6H" Q13956 12 14973022-14981865 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "retina: 67.4" "Group enriched" "Detected in some" 4 "AN3-CA: 4.2;MOLT-4: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles Vesicles "HPA045118: " "unprognostic (1.47e-3)" "unprognostic (1.07e-2)" 0.1 1.3 1.2 0.2 1.5 9.4 0.1 0.1 4.2 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 1.0 2.1 0.1 0.1 0.2 0.2 2.2 0.1 0.1 0.1 0.0 0.1 2.5 0.7 0.1 0.1 67.4 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.8 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.6 0.7 0.0 0.0 1.4 0.2 0.0 0.8 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 1.2 1.5 0.1 4.2 1.0 2.1 2.2 0.1 0.7 0.1 PDE7A HCP1 ENSG00000205268 "Phosphodiesterase 7A" Q13946 8 65717510-65842322 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 87.5;skeletal muscle: 48.3" "Cell line enhanced" "Detected in many" "Karpas-707: 32.1;MOLT-4: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018770, HPA027340" Approved "CAB018770: AB_677329, HPA027340: AB_1855127" "unprognostic (2.76e-1)" "unprognostic (2.94e-2)" "unprognostic (1.36e-1)" "unprognostic (1.17e-2)" "unprognostic (2.15e-1)" "unprognostic (7.11e-2)" "prognostic unfavourable (5.64e-4)" "unprognostic (1.44e-2)" "unprognostic (6.94e-2)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.56e-1)" "prognostic unfavourable (1.35e-4)" "unprognostic (3.08e-2)" "unprognostic (1.26e-1)" "unprognostic (5.06e-2)" "unprognostic (2.03e-2)" 6.9 1.4 4.4 22.7 4.6 12.3 10.0 7.3 4.3 7.1 4.1 5.8 5.9 5.6 3.6 8.2 3.6 3.8 6.1 21.0 4.3 3.6 13.4 2.7 10.1 27.7 4.3 2.7 3.4 9.2 1.4 7.5 4.0 4.6 7.3 5.0 3.3 11.7 12.6 48.3 4.3 13.6 4.0 3.4 16.3 6.2 4.8 5.5 87.5 13.0 25.4 22.4 5.4 4.7 7.7 2.2 5.3 0.7 2.1 12.6 1.8 4.0 3.6 15.9 7.4 2.3 2.0 6.7 3.0 2.6 3.9 3.7 4.4 2.7 11.4 0.7 1.9 4.5 5.8 6.4 4.1 13.4 3.0 8.3 5.7 3.1 1.1 6.6 3.3 2.9 10.8 2.5 7.6 3.8 6.1 32.1 2.6 2.3 53.5 8.2 16.9 1.6 20.0 2.4 2.9 2.6 8.1 7.9 9.0 3.2 1.6 1.6 8.7 17.1 2.4 5.4 6.7 3.8 2.4 15.7 6.7 19.8 5.5 13.9 2.9 0.2 0.7 5.3 3.7 0.6 6.0 6.7 5.7 3.7 1.5 7.7 12.6 9.6 2.6 2.1 0.1 2.2 4.5 1.8 4.4 4.6 7.3 4.3 4.3 3.6 4.3 2.7 4.6 5.5 PDE7B ENSG00000171408 "Phosphodiesterase 7B" Q9NP56 6 135851696-136195574 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 7.1;ASC TERT1: 8.5;EFO-21: 13.1;HeLa: 7.6;HSkMC: 18.3;HUVEC TERT2: 8.5;U-2197: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 4.3" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in all" 5 "basal ganglia: 112.3" "Low region specificity" "Detected in all" HPA023967 Uncertain Approved Nucleoplasm Nucleoplasm "HPA023967: AB_1855128" "unprognostic (3.18e-1)" "unprognostic (3.47e-1)" "unprognostic (2.34e-1)" "unprognostic (1.79e-3)" "unprognostic (3.34e-1)" "unprognostic (3.22e-4)" "unprognostic (1.37e-2)" "unprognostic (3.00e-1)" "unprognostic (2.80e-1)" "unprognostic (6.73e-3)" "unprognostic (1.11e-2)" "unprognostic (7.85e-2)" "prognostic favourable (1.59e-4)" "unprognostic (3.14e-3)" "unprognostic (2.68e-2)" "unprognostic (1.43e-1)" "unprognostic (3.34e-2)" 5.8 4.3 7.3 4.0 21.9 0.8 3.6 1.6 12.8 6.2 4.0 2.3 25.2 3.6 14.2 4.9 2.8 4.2 6.1 7.9 5.1 7.4 9.6 6.4 3.3 2.8 6.4 4.2 22.7 1.6 3.7 8.7 2.2 5.9 6.8 5.0 5.4 5.0 28.5 7.2 1.5 3.7 13.5 5.3 2.3 5.2 2.9 7.1 7.7 8.3 6.1 1.9 10.6 5.1 4.3 2.6 0.6 0.9 0.7 1.8 0.3 0.0 4.4 0.1 0.0 7.1 8.5 0.0 0.4 2.3 1.7 0.9 0.0 0.0 0.0 13.1 2.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 7.6 0.0 3.1 0.1 0.0 18.3 0.0 3.4 0.0 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.0 0.5 3.1 2.9 0.1 0.1 0.0 1.5 0.0 1.8 0.0 9.1 0.0 0.1 0.0 0.0 0.5 0.0 0.7 0.2 0.9 0.6 0.2 0.2 0.1 1.5 0.4 0.2 2.6 4.3 1.8 1.0 0.3 0.7 0.1 0.2 0.2 0.3 7.3 21.9 1.6 12.8 5.1 7.4 6.4 4.2 5.9 7.1 PDE8A HsT19550 ENSG00000073417 "Phosphodiesterase 8A" O60658 15 84980440-85139145 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007722 Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA007722: AB_1855130" "unprognostic (1.68e-1)" "unprognostic (2.83e-2)" "unprognostic (4.81e-2)" "unprognostic (4.97e-2)" "unprognostic (6.25e-2)" "unprognostic (3.47e-2)" "unprognostic (2.97e-2)" "unprognostic (3.94e-2)" "unprognostic (1.03e-1)" "unprognostic (2.45e-1)" "unprognostic (8.99e-3)" "unprognostic (2.75e-2)" "unprognostic (3.42e-1)" "unprognostic (3.72e-1)" "unprognostic (4.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.94e-2)" 14.3 16.6 14.0 8.5 18.7 2.6 9.8 2.6 14.8 11.4 21.0 35.5 9.1 13.2 9.0 8.2 5.9 8.8 14.3 7.8 17.2 9.8 21.7 26.2 10.5 5.4 23.3 12.1 12.0 12.7 17.6 7.1 10.1 20.1 6.9 19.8 12.6 8.2 9.2 5.6 6.2 11.7 10.7 17.6 6.7 10.8 10.6 25.5 2.2 11.2 4.8 5.0 11.9 10.6 1.3 1.7 1.7 4.5 0.6 3.2 0.6 12.6 21.1 3.6 2.4 15.2 8.1 4.3 8.4 9.5 7.6 8.8 4.7 7.5 2.5 6.7 11.4 9.0 15.3 6.7 10.2 4.6 9.1 3.4 13.7 6.8 11.0 1.9 5.1 8.1 4.1 8.9 8.5 9.7 6.7 8.3 6.8 10.6 1.1 1.9 1.7 3.9 1.5 2.9 3.5 6.0 39.5 8.4 6.4 8.4 9.2 24.6 3.0 3.8 7.6 17.8 6.2 6.3 13.8 4.0 7.1 2.7 12.1 7.9 5.0 0.0 2.4 1.7 1.1 2.2 2.1 0.8 1.8 1.9 1.7 1.3 2.2 0.9 0.2 0.6 4.5 0.0 3.2 0.6 14.0 18.7 2.6 14.8 17.2 9.8 23.3 12.1 20.1 25.5 PDE8B ENSG00000113231 "Phosphodiesterase 8B" O95263 5 77210449-77429807 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "Cushing syndrome, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "thyroid gland: 67.7" "Group enriched" "Detected in some" 4 "BJ hTERT+: 12.1;HeLa: 27.8;SK-BR-3: 7.4" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 35.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "HPA036911, HPA036912" Supported Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA036911: , HPA036912: AB_10670377" "unprognostic (1.30e-1)" "unprognostic (7.95e-2)" "unprognostic (3.35e-2)" "unprognostic (7.61e-4)" "unprognostic (1.59e-2)" "unprognostic (1.41e-1)" "unprognostic (2.66e-2)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.26e-2)" "unprognostic (3.98e-2)" "unprognostic (2.44e-1)" "unprognostic (9.04e-3)" "unprognostic (3.40e-2)" "unprognostic (3.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.19e-2)" 6.8 2.5 9.9 0.7 14.2 0.4 3.8 1.1 16.3 6.3 1.2 2.3 0.3 1.2 11.3 3.2 1.1 10.1 2.1 7.9 8.2 9.2 3.1 1.2 2.2 0.7 5.4 8.3 1.9 4.2 0.3 3.8 13.1 8.6 10.5 0.8 2.0 5.3 7.1 0.4 0.7 1.3 10.3 2.3 0.4 1.5 1.5 5.7 0.3 67.7 0.3 0.7 0.8 1.4 0.2 0.8 1.4 2.3 0.4 0.4 0.1 0.3 3.3 1.3 0.3 1.2 0.0 0.5 1.1 12.1 0.2 0.1 1.3 0.2 0.5 0.2 0.1 0.9 0.1 0.0 0.2 0.2 1.0 0.7 27.8 0.3 0.0 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.6 0.7 0.8 0.1 0.8 1.4 0.7 0.0 0.3 3.7 1.0 1.6 7.4 0.8 1.6 1.1 0.6 0.4 0.2 0.2 0.6 0.9 0.5 0.6 1.6 0.7 0.4 0.0 0.3 1.4 0.3 2.2 0.1 0.2 0.2 0.3 0.8 0.2 0.4 0.0 0.3 0.4 2.3 0.5 0.1 0.1 9.9 14.2 1.1 16.3 8.2 9.2 5.4 8.3 8.6 5.7 PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653636-42775509 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 16.1;EFO-21: 16.2;MCF7: 12.0;NB-4: 17.9;NTERA-2: 22.1;SCLC-21H: 12.3" "Cancer enhanced" "Detected in all" "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 6.8" "Group enriched" "Detected in many" 4 "NK-cells: 1.7;T-cells: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011380 Enhanced Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA011380: AB_1855132" "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" 6.1 6.6 9.9 6.8 15.2 0.8 9.4 13.7 9.0 3.7 37.1 11.9 14.0 3.0 5.7 18.8 6.1 10.3 7.7 3.5 6.2 7.7 13.2 2.5 4.7 4.6 10.0 4.9 4.1 4.0 4.7 6.0 9.6 6.9 33.2 15.8 9.7 8.8 15.9 2.3 3.8 26.1 22.3 8.0 15.9 8.4 1.5 8.9 4.9 5.2 2.1 4.1 12.6 4.0 0.5 0.9 1.0 0.1 1.7 6.8 0.5 0.0 1.5 16.1 1.9 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.7 9.7 0.0 16.2 0.0 0.0 1.4 5.2 0.0 0.0 5.5 0.0 0.0 3.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 12.0 0.8 17.9 22.1 0.0 0.0 0.0 0.6 11.0 4.4 12.3 7.3 2.7 0.0 0.2 0.1 9.9 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.1 0.6 0.2 0.5 6.8 1.7 1.0 1.7 0.1 0.9 2.2 0.5 9.9 15.2 13.7 6.7 6.2 7.7 10.0 4.9 6.9 8.9 PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69328621-69330595 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Mitochondria Nucleoplasm "HPA063409: " "unprognostic (4.28e-2)" "prognostic unfavourable (4.63e-4)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-1)" "prognostic unfavourable (2.73e-4)" "unprognostic (2.98e-3)" "prognostic unfavourable (7.35e-4)" "unprognostic (5.84e-2)" "unprognostic (4.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.00e-1)" "prognostic favourable (6.11e-4)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-2)" 6.6 7.9 4.8 7.8 4.5 5.3 4.8 3.1 6.9 3.6 7.6 3.8 3.3 7.1 5.3 5.6 8.4 4.4 6.5 3.8 4.6 3.3 14.9 30.2 3.7 7.0 3.0 5.2 5.0 14.2 8.2 3.9 4.9 4.4 5.3 4.1 4.3 12.8 4.6 10.4 6.0 5.2 3.4 2.3 5.0 8.3 3.7 2.0 10.2 7.3 9.2 6.2 3.7 4.0 10.3 3.2 2.5 2.8 1.7 6.9 1.5 8.9 6.0 1.2 2.9 1.8 1.3 10.6 7.5 2.0 5.4 4.7 14.9 6.4 16.6 10.0 2.6 12.9 3.7 4.0 2.2 4.0 30.8 8.4 5.7 21.3 3.7 11.7 6.7 2.8 7.1 4.8 2.3 3.1 20.2 1.9 2.9 11.5 9.1 12.3 7.7 11.1 21.6 1.9 15.4 4.3 5.6 10.3 8.2 13.0 2.2 6.3 12.8 3.8 4.6 4.6 8.8 5.4 8.7 15.7 10.4 19.6 3.1 8.7 6.0 0.0 2.8 2.5 1.2 1.6 3.1 4.3 3.9 3.9 3.0 10.3 6.9 2.5 0.0 1.7 1.5 3.2 3.0 1.5 4.8 4.5 3.1 6.9 4.6 3.3 3.0 5.2 4.4 2.0 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229097-54298247 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 81.5" "Cell line enhanced" "Detected in some" "ASC diff: 81.0;ASC TERT1: 37.9;BJ hTERT+: 47.0;fHDF/TERT166: 32.7;HHSteC: 27.4;HSkMC: 68.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" 150000 "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: " "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favourable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavourable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 35.0 12.4 12.6 16.1 7.6 0.9 17.2 2.4 20.1 33.2 19.1 9.2 6.4 9.6 27.6 14.6 21.9 22.5 16.2 15.3 8.9 7.4 22.8 8.4 24.1 26.9 9.2 4.0 81.5 6.8 1.6 2.1 25.1 7.2 18.6 15.2 19.2 8.5 8.3 11.9 7.0 17.4 19.7 8.8 51.6 13.6 19.0 9.3 0.5 11.3 12.8 4.3 35.9 24.6 0.9 0.4 2.5 0.4 0.3 0.8 0.3 0.0 0.0 0.2 0.1 81.0 37.9 0.1 4.2 47.0 0.0 0.1 11.2 0.0 0.1 0.1 32.7 0.1 3.2 0.0 0.0 0.4 0.1 0.1 0.1 0.2 27.4 0.0 0.0 68.9 0.0 5.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.3 0.1 6.6 0.0 0.1 0.0 0.1 0.0 0.1 14.8 0.5 16.2 0.0 0.0 0.0 0.1 0.4 0.0 0.3 2.5 0.4 0.2 0.5 0.2 0.2 0.6 0.8 0.4 0.0 0.9 0.7 0.4 2.3 0.3 0.3 0.4 0.2 0.3 12.6 7.6 2.4 7.3 8.9 7.4 9.2 4.0 7.2 9.3 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113837-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "ASC diff: 169.0;ASC TERT1: 58.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.9;non-classical monocyte: 4.1" "Group enriched" "Detected in many" 8 "monocytes: 4.1;T-cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" 35000000 Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavourable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavourable (8.11e-4)" 61.8 10.4 8.3 11.0 9.1 0.5 66.1 4.6 10.4 73.1 15.7 6.7 6.9 5.1 44.3 17.3 21.7 26.1 51.7 24.2 8.2 3.9 17.0 4.6 28.9 21.5 7.9 8.1 46.5 7.5 10.4 7.7 46.4 7.7 24.2 6.3 22.9 11.2 19.3 29.8 20.3 11.2 29.8 5.0 19.6 9.2 21.5 6.7 1.4 21.4 16.0 7.3 23.6 35.1 0.4 0.1 0.0 4.1 0.0 2.9 0.6 0.0 0.0 1.0 0.0 169.0 58.5 0.3 5.9 24.5 4.1 7.0 0.6 0.0 0.0 0.7 16.9 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.4 24.0 0.0 0.0 26.3 0.0 5.7 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 1.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 6.7 2.2 2.8 0.3 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 2.9 0.6 0.0 0.4 0.1 0.8 0.1 0.1 0.0 1.3 0.0 0.0 4.1 0.0 0.0 0.6 8.3 9.1 4.6 10.4 8.2 3.9 7.9 8.1 7.7 6.7 PDHA1 PDHA ENSG00000131828 "Pyruvate dehydrogenase E1 alpha 1 subunit" P08559 X 19343893-19361705 "Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease mutation, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 107.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria "Intracellular and membrane" 15000 Mitochondria "HPA047487: , HPA047864: , HPA063053: " "unprognostic (5.71e-3)" "unprognostic (2.46e-3)" "unprognostic (5.71e-2)" "unprognostic (3.36e-3)" "unprognostic (3.12e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-2)" "unprognostic (4.28e-1)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (6.90e-2)" "unprognostic (8.68e-2)" "prognostic favourable (1.13e-7)" "unprognostic (3.72e-2)" "unprognostic (3.03e-1)" "unprognostic (1.92e-2)" "unprognostic (9.06e-2)" 22.5 16.1 14.7 11.7 24.3 20.4 14.7 18.6 25.0 12.3 28.6 13.0 27.7 22.7 13.0 21.6 17.2 12.4 11.8 89.3 15.5 12.2 36.6 26.6 10.5 8.9 14.8 19.9 12.2 28.7 25.0 11.6 14.9 19.0 10.8 28.2 12.7 41.8 18.3 107.3 12.7 21.1 21.2 12.7 11.5 24.9 6.3 12.0 11.3 15.0 44.9 14.9 13.1 12.4 39.4 45.1 34.8 46.1 35.5 36.6 31.9 25.7 32.1 23.3 24.5 22.6 17.3 28.6 17.8 15.9 37.0 28.6 45.7 16.6 44.1 13.2 21.4 33.7 71.4 30.9 39.0 14.6 39.8 21.9 55.3 40.2 24.0 34.9 17.9 22.3 28.8 34.1 33.8 22.4 19.2 18.7 25.8 34.1 29.1 35.9 23.7 56.2 30.1 39.0 54.0 63.6 26.4 12.9 13.7 28.4 36.0 32.2 38.0 24.5 13.9 19.1 17.2 52.0 22.5 15.9 16.4 29.2 18.0 24.5 16.5 34.8 35.0 24.2 30.3 46.1 36.6 39.4 29.4 32.8 45.1 29.3 29.0 30.6 6.1 35.5 39.1 29.8 31.1 31.9 14.7 24.3 18.6 25.0 15.5 12.2 14.8 19.9 19.0 12.0 PDHA2 PDHAL ENSG00000163114 "Pyruvate dehydrogenase E1 alpha 2 subunit" P29803 4 95840019-95841474 "Citric acid cycle related proteins, Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 146 "testis: 60.5" "Cell line enhanced" "Detected in single" "BEWO: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria Mitochondria "HPA047487: , HPA047864: , HPA063053: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PDHB PDHE1B ENSG00000168291 "Pyruvate dehydrogenase E1 beta subunit" P11177 3 58427630-58433857 "Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033794, HPA036744, HPA036745" Enhanced Supported Nucleoplasm,Mitochondria 6500000 Mitochondria Nucleoplasm "CAB033794: AB_2162946, HPA036744: AB_10670921, HPA036745: AB_2675285" "unprognostic (2.06e-2)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (7.22e-2)" "unprognostic (1.42e-1)" "unprognostic (3.20e-2)" "unprognostic (6.13e-2)" "unprognostic (9.62e-2)" "unprognostic (5.94e-2)" "unprognostic (3.98e-1)" "unprognostic (2.35e-1)" "prognostic favourable (2.79e-8)" "unprognostic (2.67e-1)" "unprognostic (8.37e-2)" "unprognostic (1.06e-2)" "unprognostic (9.85e-2)" 21.8 34.3 22.5 19.5 28.4 8.6 17.1 15.1 26.2 18.0 21.6 18.4 19.2 16.2 17.2 18.2 22.8 15.0 16.5 64.2 24.1 20.8 38.7 41.8 13.9 18.2 23.7 23.3 11.0 17.2 26.0 20.0 21.6 26.4 19.5 23.9 16.1 17.6 22.1 92.2 14.3 17.3 24.5 22.8 23.2 21.4 21.8 17.5 20.9 16.1 33.8 20.6 17.9 14.4 37.0 50.1 33.6 39.8 43.4 38.6 38.3 19.0 26.7 27.7 20.8 28.2 34.7 33.2 24.1 30.2 35.6 36.7 48.1 18.5 40.7 13.6 30.4 11.1 33.7 22.1 27.3 23.5 24.7 36.3 50.4 36.3 28.5 29.4 20.4 30.2 20.4 28.7 16.9 30.6 18.7 18.4 38.6 18.2 27.8 31.0 38.1 30.3 13.3 21.6 39.2 56.2 26.1 19.2 21.2 22.3 32.1 23.9 47.5 31.6 22.4 19.1 25.4 20.0 27.2 25.7 36.5 28.7 29.3 35.0 18.0 16.4 35.4 33.6 31.5 39.8 33.2 37.0 31.2 30.0 50.1 33.3 35.1 31.4 7.0 43.4 35.9 33.7 38.6 38.3 22.5 28.4 15.1 26.2 24.1 20.8 23.7 23.3 26.4 17.5 PDIA2 "PDA2, PDI, PDIP, PDIR" ENSG00000185615 "Protein disulfide isomerase family A member 2" Q13087 16 283152-287215 "Enzymes, Predicted intracellular proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "pancreas: 286.5" "Cell line enhanced" "Detected in some" "HAP1: 5.1;HEK 293: 11.3;Hep G2: 8.4;Karpas-707: 3.9;MCF7: 6.0;SH-SY5Y: 4.9" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 28.6" "Region enhanced" "Detected in many" "cerebellum: 15.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA051692, HPA053492" Enhanced "Intracellular and membrane" "HPA051692: AB_2681575, HPA053492: AB_2682169" "unprognostic (3.46e-2)" "unprognostic (7.98e-3)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" "unprognostic (2.17e-2)" "unprognostic (6.27e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-1)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (2.90e-2)" "unprognostic (1.58e-14)" "unprognostic (3.06e-2)" "unprognostic (1.66e-1)" "unprognostic (8.75e-2)" "unprognostic (2.87e-2)" 0.3 0.3 2.1 0.2 1.5 0.3 0.2 15.3 3.0 0.2 0.7 4.3 0.2 2.9 0.2 0.3 0.2 0.2 0.8 0.4 2.8 3.0 0.2 0.2 0.2 0.2 4.0 0.5 0.4 286.5 0.2 0.2 0.5 2.2 0.2 0.2 0.2 0.3 0.2 0.2 0.2 1.0 0.2 5.4 0.2 10.2 0.3 2.8 0.1 0.2 0.2 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.1 0.1 5.1 0.2 0.6 0.1 11.3 0.0 0.3 8.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.4 3.9 0.2 6.0 0.2 0.6 0.4 0.0 0.1 0.0 1.1 0.0 0.0 2.2 4.9 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 1.5 15.3 3.0 2.8 3.0 4.0 0.5 2.2 2.8 PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746392-43773279 "Enzymes, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" 390000000 "Endoplasmic reticulum" "CAB011199: AB_609902, CAB015181: AB_2160857, CAB075744: , HPA002645: AB_1079031, HPA003230: AB_1079030" "unprognostic (9.20e-2)" "unprognostic (1.21e-3)" "unprognostic (1.34e-1)" "prognostic favourable (2.05e-4)" "unprognostic (2.40e-2)" "prognostic unfavourable (8.95e-5)" "unprognostic (1.67e-1)" "unprognostic (8.60e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.10e-1)" "prognostic unfavourable (2.11e-8)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (6.63e-2)" 16.9 21.2 10.0 20.5 13.5 20.8 31.1 12.7 9.2 24.7 19.4 12.3 33.9 22.2 19.7 42.4 21.7 18.4 25.1 20.6 10.2 12.7 27.3 112.5 20.0 34.6 12.4 10.3 22.4 46.8 21.1 21.7 44.0 13.3 24.6 21.2 13.7 43.4 36.9 8.7 17.9 28.8 15.8 11.4 25.2 20.5 17.1 14.3 15.6 74.0 16.4 19.8 14.7 28.3 7.7 18.3 13.5 10.8 11.7 14.1 14.5 12.2 4.6 9.7 21.8 19.8 21.2 29.9 24.6 24.3 18.3 22.7 12.8 12.6 14.0 16.0 28.0 19.5 12.3 23.8 15.9 10.1 18.2 18.9 7.3 11.8 32.5 10.7 13.8 13.6 19.7 13.8 23.3 31.8 10.9 6.9 17.8 4.2 3.6 12.1 9.8 18.6 7.0 15.3 10.5 15.5 10.0 9.8 10.9 20.5 19.7 7.7 13.7 10.9 21.5 15.2 8.0 12.2 11.9 3.1 3.6 14.7 19.5 16.9 11.4 10.0 10.3 13.5 13.4 10.5 14.1 6.5 8.5 10.8 9.6 7.7 7.2 8.4 2.9 11.7 10.8 18.3 6.7 14.5 10.0 13.5 12.7 9.2 10.2 12.7 12.4 10.3 13.3 14.3 PDIA4 "ERP70, ERP72" ENSG00000155660 "Protein disulfide isomerase family A member 4" P13667 7 149003062-149028641 "Enzymes, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 164.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006139, HPA006140, CAB017368" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" 12000000 "Endoplasmic reticulum" "CAB017368: AB_10621725, HPA006139: AB_1848256, HPA006140: AB_1848257" "unprognostic (1.98e-1)" "unprognostic (1.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.87e-2)" "prognostic unfavourable (9.69e-4)" "unprognostic (1.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.11e-2)" "unprognostic (5.11e-2)" "unprognostic (3.24e-3)" "unprognostic (6.08e-3)" "unprognostic (3.20e-2)" "prognostic unfavourable (5.20e-9)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" 17.6 13.0 7.7 25.6 11.9 7.4 27.4 5.1 7.9 25.5 20.9 12.1 28.8 18.2 19.4 46.3 15.2 20.8 28.1 16.9 7.3 8.0 27.7 164.3 19.1 29.1 11.6 6.2 19.4 76.3 7.0 19.1 24.7 12.0 18.0 21.9 7.8 36.4 26.5 5.8 10.1 21.3 17.8 13.9 27.9 23.7 11.5 11.3 19.2 89.8 11.9 24.3 17.4 22.6 26.6 63.3 16.2 21.2 21.5 35.9 34.5 32.6 31.1 33.8 94.5 30.9 22.1 49.0 46.0 30.8 26.4 43.1 25.8 88.4 23.5 103.3 37.8 21.4 22.8 43.6 23.2 16.7 13.4 11.3 9.0 56.5 41.5 25.7 31.9 21.7 19.6 28.9 23.2 53.5 18.4 64.2 23.1 35.7 24.4 29.3 50.4 18.1 16.1 26.2 57.0 30.8 25.7 10.8 28.4 41.7 30.1 16.0 17.1 19.8 29.2 20.8 11.8 50.5 32.3 48.9 22.0 16.6 48.6 30.4 70.8 16.2 20.1 12.1 34.3 21.2 35.9 26.6 22.6 26.7 19.4 15.1 21.5 22.7 2.7 21.5 21.0 63.3 16.6 34.5 7.7 11.9 5.1 7.9 7.3 8.0 11.6 6.2 12.0 11.3 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067062-123225227 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 66.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" 2900000 "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favourable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavourable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 11.6 17.1 2.6 11.2 3.1 6.3 9.3 1.0 4.0 10.0 11.0 2.4 10.9 5.6 12.2 17.1 6.7 9.1 22.2 7.2 2.5 1.2 11.0 66.0 14.4 7.1 2.2 1.8 11.4 18.3 5.2 12.1 29.1 1.9 14.3 10.8 12.7 10.8 7.6 8.1 6.1 8.2 9.5 2.3 8.6 17.6 18.0 2.5 3.2 18.2 5.5 7.9 7.8 6.9 3.2 12.8 0.3 9.0 0.5 2.4 2.3 8.1 5.0 6.3 7.6 28.9 26.2 33.6 15.5 26.0 8.7 24.0 16.0 7.5 0.0 20.3 24.0 4.3 2.7 9.4 9.2 0.2 3.1 3.6 1.5 19.1 12.0 8.9 0.5 22.5 14.2 5.9 12.4 29.4 4.5 21.3 5.9 9.9 2.4 10.5 4.6 5.2 2.3 4.5 22.5 7.3 4.8 6.8 4.1 7.5 8.5 13.3 7.4 11.0 16.3 2.2 7.1 10.5 4.2 6.3 1.6 3.6 7.2 7.1 7.5 0.0 9.0 0.3 1.4 2.2 2.4 3.2 1.0 0.9 5.4 0.8 0.6 0.6 0.2 0.5 0.4 12.8 0.0 2.3 2.6 3.1 1.0 4.0 2.5 1.2 2.2 1.8 1.9 2.5 PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" 53000000 "Endoplasmic reticulum, Cytosol" "CAB034347: AB_2299360, HPA034652: AB_2674263, HPA034653: AB_10601982" "unprognostic (8.16e-2)" "prognostic unfavourable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (1.20e-4)" "prognostic unfavourable (3.63e-5)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" "unprognostic (5.25e-3)" "unprognostic (6.03e-3)" "unprognostic (1.68e-1)" "prognostic unfavourable (2.51e-6)" "unprognostic (6.59e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-2)" "unprognostic (3.69e-3)" 26.9 32.7 16.7 25.0 29.9 19.9 28.7 11.3 16.8 33.4 26.1 13.9 53.7 20.4 30.4 76.1 27.1 25.5 22.4 32.7 14.2 13.9 42.1 118.4 30.4 36.3 17.8 12.7 26.5 141.6 24.9 23.3 39.5 19.0 22.6 30.1 14.6 53.4 45.0 15.7 16.1 28.4 26.5 14.3 35.1 30.9 12.4 19.5 18.1 97.9 20.1 29.7 21.9 30.6 45.2 61.0 52.0 46.2 51.5 52.2 59.7 33.9 36.9 52.9 82.9 68.1 58.9 94.0 82.7 76.8 43.4 58.5 52.3 67.1 55.2 58.2 80.8 27.9 39.7 69.2 46.7 43.2 31.3 44.7 28.9 84.9 73.7 45.8 33.6 42.5 53.2 42.0 75.8 97.8 38.4 119.1 42.8 40.2 17.6 47.5 44.1 29.2 42.3 53.9 99.9 61.8 41.1 33.9 67.9 32.6 47.8 46.4 16.9 77.7 48.0 40.8 52.1 36.7 47.8 112.4 69.3 35.8 55.1 57.6 57.0 52.0 44.4 20.5 47.5 46.2 52.2 45.2 37.7 44.7 48.6 33.1 18.4 31.0 8.1 51.5 33.9 61.0 37.7 59.7 16.7 29.9 11.3 16.8 14.2 13.9 17.8 12.7 19.0 19.5 PDIK1L CLIK1L ENSG00000175087 "PDLIM1 interacting kinase 1 like" Q8N165 1 26111165-26125543 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064157 Supported Nucleoplasm Nucleoplasm "HPA064157: " "unprognostic (1.09e-1)" "unprognostic (1.81e-3)" "unprognostic (2.99e-3)" "unprognostic (2.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.34e-3)" "unprognostic (3.93e-2)" "unprognostic (1.72e-3)" "unprognostic (7.29e-3)" "unprognostic (1.08e-1)" "unprognostic (2.42e-2)" "unprognostic (3.59e-1)" "unprognostic (1.34e-2)" "unprognostic (4.24e-3)" "unprognostic (2.94e-1)" "unprognostic (4.47e-1)" "unprognostic (1.78e-2)" 7.0 6.0 8.6 6.2 12.3 19.9 11.5 17.8 15.9 8.6 8.9 7.1 7.6 9.5 7.8 6.4 11.4 7.5 5.8 4.8 8.5 10.6 8.5 11.3 6.7 8.0 9.3 9.9 10.2 15.3 10.7 9.9 5.6 11.5 6.8 10.6 6.1 10.2 8.9 7.7 9.4 9.7 6.5 8.3 8.3 10.2 7.8 9.3 19.1 22.2 6.7 8.8 8.8 8.0 6.7 9.3 11.0 6.1 5.6 10.4 5.2 5.5 2.1 5.8 7.3 2.2 3.0 1.9 1.4 2.0 3.7 2.4 1.4 7.9 11.6 4.2 2.1 4.1 7.8 2.9 3.6 4.1 5.2 10.3 3.3 1.5 3.4 10.8 6.2 1.6 4.2 3.3 6.7 3.3 12.2 11.6 1.2 3.1 15.7 4.8 2.6 3.1 8.4 5.3 13.9 2.5 4.3 9.3 7.9 5.6 7.1 7.2 4.0 3.7 3.1 4.1 3.6 5.2 4.5 17.3 17.1 8.8 4.3 13.4 3.8 11.0 5.0 4.2 6.7 4.6 6.2 6.7 9.4 7.4 9.3 5.6 10.0 8.0 0.5 5.6 6.1 3.5 10.4 5.2 8.6 12.3 17.8 15.9 8.5 10.6 9.3 9.9 11.5 9.3 PDK1 ENSG00000152256 "Pyruvate dehydrogenase kinase 1" Q15118 2 172555373-172608669 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 31.3;U-87 MG: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 5.9;granulocytes: 16.0;T-cells: 15.8" "Low region specificity" "Detected in all" "CAB017554, HPA027376, HPA059083" Approved Approved Nucleoli,Mitochondria 22000 "Nucleoli, Mitochondria" "CAB017554: AB_2161138, HPA027376: AB_1855139, HPA059083: " "unprognostic (2.14e-1)" "prognostic unfavourable (7.30e-5)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "unprognostic (6.47e-2)" "unprognostic (1.58e-1)" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (9.69e-3)" "unprognostic (6.44e-2)" "unprognostic (5.44e-3)" "unprognostic (1.55e-1)" "prognostic unfavourable (1.10e-8)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" "unprognostic (2.56e-2)" "unprognostic (5.34e-2)" 9.9 16.2 6.8 11.0 10.5 13.4 16.7 7.1 15.6 7.3 15.3 3.3 2.9 15.5 5.4 8.0 11.2 4.4 5.8 27.6 6.9 5.2 6.8 14.2 6.1 21.4 7.2 5.2 19.5 7.2 3.4 7.5 7.9 7.2 6.5 13.1 7.6 14.1 7.6 9.6 24.7 8.4 5.2 10.7 14.2 12.5 11.0 6.7 10.3 5.1 5.0 20.8 18.0 9.8 5.9 2.3 16.0 2.2 1.4 15.8 6.2 14.1 0.6 3.7 9.1 1.5 2.3 5.2 12.5 10.1 6.3 13.4 3.6 3.0 13.5 6.9 3.8 6.2 2.5 7.8 20.1 2.7 5.0 16.4 3.3 4.2 2.7 8.1 6.1 2.9 2.8 4.3 7.3 3.3 3.4 9.3 8.3 1.4 5.1 10.2 8.9 3.9 5.4 6.0 21.7 3.2 4.6 6.9 7.9 3.2 3.8 4.7 2.4 3.4 3.8 10.0 3.2 5.2 3.3 31.3 18.1 11.1 32.0 5.9 2.0 12.2 2.2 16.0 2.5 1.5 3.0 4.7 4.2 2.8 2.3 5.9 15.8 9.6 8.5 1.4 1.9 0.4 8.0 6.2 6.8 10.5 7.1 15.6 6.9 5.2 7.2 5.2 7.2 6.7 PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 101.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA008287: AB_1079589" "unprognostic (2.74e-2)" "prognostic favourable (5.87e-4)" "unprognostic (1.16e-1)" "unprognostic (2.43e-3)" "unprognostic (1.22e-1)" "unprognostic (9.63e-3)" "unprognostic (9.80e-3)" "unprognostic (8.39e-3)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "prognostic favourable (9.59e-5)" "unprognostic (3.81e-1)" "unprognostic (2.54e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" 20.6 26.1 17.2 5.2 27.5 3.2 10.8 53.7 34.4 10.1 16.1 16.1 10.1 15.5 13.1 69.8 12.5 14.4 11.5 51.7 18.2 13.0 33.7 27.8 9.0 5.7 14.6 20.9 27.7 24.1 16.9 7.5 8.6 14.2 12.7 12.4 19.5 14.0 16.5 101.0 10.6 16.5 15.1 9.9 7.8 13.6 7.2 11.4 6.2 15.6 31.4 7.4 13.8 9.4 11.3 20.1 8.9 12.9 16.5 17.4 12.2 6.4 9.4 11.3 10.1 11.9 9.0 1.2 7.1 10.5 10.6 10.3 0.9 7.1 8.2 11.9 19.8 3.1 7.5 2.8 10.5 16.5 10.4 7.3 9.2 6.9 6.4 0.0 8.0 18.9 11.0 6.9 0.5 9.2 2.9 8.2 6.0 8.3 6.1 0.0 2.4 9.1 9.2 25.2 11.1 5.8 5.5 7.5 11.4 10.0 3.2 4.7 18.5 7.3 4.7 12.5 10.3 8.5 5.1 16.2 15.3 4.4 18.3 2.6 8.0 8.9 12.9 6.8 14.0 9.8 11.1 11.1 12.5 14.8 14.2 11.3 14.6 15.0 2.2 16.5 10.5 20.1 17.4 12.2 17.2 27.5 53.7 34.4 18.2 13.0 14.6 20.9 14.2 11.4 PDK3 ENSG00000067992 "Pyruvate dehydrogenase kinase 3" Q15120 X 24465221-24539837 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046583, HPA072492" Approved Supported Nucleoli,Mitochondria Mitochondria Nucleoli "HPA046583: , HPA072492: " "unprognostic (5.41e-3)" "unprognostic (5.43e-3)" "unprognostic (5.35e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-3)" "unprognostic (5.38e-2)" "prognostic unfavourable (2.76e-4)" "unprognostic (1.51e-1)" "unprognostic (5.57e-2)" "unprognostic (1.35e-1)" "unprognostic (1.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "unprognostic (1.02e-1)" "unprognostic (2.92e-1)" "unprognostic (2.28e-2)" "unprognostic (9.43e-3)" 9.6 5.6 5.7 9.8 17.3 16.3 12.8 3.3 23.6 8.0 14.7 5.5 5.6 13.6 7.3 15.7 9.5 13.2 7.0 16.9 12.5 6.8 13.7 11.1 11.2 13.4 6.2 13.7 11.0 7.3 12.8 14.1 7.7 14.9 8.3 10.1 9.9 19.3 5.2 3.9 14.2 15.6 8.6 6.1 17.9 12.7 23.1 4.8 12.5 6.2 4.1 14.9 10.3 9.2 4.5 7.2 36.4 10.9 7.1 11.0 6.7 9.0 4.6 3.9 6.5 0.1 0.0 4.1 2.7 2.4 3.7 6.5 0.4 11.0 9.1 1.8 0.7 2.0 11.3 6.9 9.9 7.8 5.4 4.9 5.3 2.6 1.3 4.1 4.8 0.7 3.0 0.9 0.9 5.5 0.9 13.9 0.5 16.9 7.8 5.4 7.0 5.4 4.0 7.0 13.4 3.2 17.6 2.5 3.2 14.7 6.0 4.5 8.2 1.6 0.1 2.6 3.8 4.8 3.2 8.9 6.8 11.0 7.1 6.4 5.3 9.4 8.9 21.3 7.6 10.9 11.0 4.5 6.2 6.2 7.2 4.1 4.9 5.7 36.4 7.1 10.4 2.3 5.1 6.7 5.7 17.3 3.3 23.6 12.5 6.8 6.2 13.7 14.9 4.8 PDK4 ENSG00000004799 "Pyruvate dehydrogenase kinase 4" Q16654 7 95583499-95596491 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 351.0;skeletal muscle: 497.0" "Cell line enriched" "Detected in some" 7 "ASC diff: 104.7" "Cancer enhanced" "Detected in all" "renal cancer: 107.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 14.2;eosinophil: 15.6;intermediate monocyte: 26.1;myeloid DC: 7.1;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 11 "dendritic cells: 7.1;granulocytes: 15.6;monocytes: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA056731 Approved "HPA056731: " "unprognostic (3.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.47e-1)" "unprognostic (6.38e-2)" "unprognostic (2.24e-3)" "unprognostic (1.87e-2)" "unprognostic (8.75e-2)" "unprognostic (2.41e-2)" "prognostic unfavourable (1.80e-4)" "unprognostic (9.15e-2)" "unprognostic (4.20e-2)" "unprognostic (1.12e-1)" 90.7 41.9 6.9 5.9 14.6 0.4 49.1 2.5 9.1 12.3 30.9 9.0 150.6 13.6 10.7 13.7 29.0 14.7 15.6 351.0 9.2 3.7 27.7 39.5 14.1 6.1 18.2 2.4 46.6 102.9 0.8 8.1 19.4 26.1 29.3 8.4 4.4 8.4 150.6 497.0 10.2 46.2 20.7 13.9 19.0 21.2 10.8 17.4 1.0 13.4 12.3 2.5 23.8 46.4 0.7 7.1 15.6 26.1 1.4 0.0 4.7 0.0 7.8 0.3 2.0 104.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.3 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.0 0.5 0.1 0.5 0.0 0.6 1.6 0.2 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 14.2 15.6 0.0 26.1 0.0 0.1 0.0 0.0 7.1 0.7 0.0 0.0 1.0 1.4 15.6 0.2 0.0 4.7 6.9 14.6 2.5 9.1 9.2 3.7 18.2 2.4 26.1 17.4 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926066 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 33.2;TIME: 33.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 38.9;cerebral cortex: 62.2;olfactory region: 32.5" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol Nucleoplasm "Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavourable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favourable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 5.1 32.3 11.0 4.6 38.9 5.9 7.9 7.5 62.2 7.5 4.3 4.7 1.6 3.3 7.7 8.6 8.0 6.1 9.6 22.9 10.1 8.0 6.3 2.2 6.0 5.6 5.1 32.5 9.7 9.3 20.6 4.2 6.6 4.4 5.2 6.2 4.4 6.6 4.7 31.8 3.2 5.5 5.5 3.4 5.8 5.5 12.9 4.8 4.1 9.3 7.0 5.8 7.7 5.1 11.0 12.7 7.8 21.5 2.8 19.5 8.8 8.9 4.4 9.6 4.0 8.0 14.6 3.2 7.0 7.8 8.3 9.8 4.6 33.2 5.0 23.7 11.2 19.9 4.1 5.9 12.3 0.5 2.0 2.3 5.5 1.6 9.1 1.1 3.3 9.4 11.8 14.1 22.6 18.7 0.8 8.2 10.1 2.1 6.9 3.6 4.4 5.7 1.7 5.7 0.9 5.7 6.2 0.8 4.2 4.6 0.5 21.6 1.5 1.4 33.2 10.1 6.5 23.6 8.3 4.6 1.9 4.2 12.9 4.2 8.9 3.1 15.4 7.8 5.6 14.3 5.3 9.3 9.1 7.2 12.7 11.0 5.5 4.8 1.8 2.8 21.5 2.1 19.5 8.8 11.0 38.9 7.5 62.2 10.1 8.0 5.1 32.5 4.4 4.8 PDP2 "KIAA1348, PPM2B, PPM2C2" ENSG00000172840 "Pyruvate dehyrogenase phosphatase catalytic subunit 2" Q9P2J9 16 66878589-66895754 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019950, HPA062059" Approved Supported Mitochondria Mitochondria "HPA019950: AB_1855156, HPA062059: " "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (5.44e-2)" "unprognostic (1.17e-1)" "unprognostic (4.90e-3)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "prognostic favourable (9.75e-7)" "unprognostic (1.89e-1)" "unprognostic (5.10e-1)" "unprognostic (3.20e-1)" "unprognostic (6.15e-2)" 10.7 7.2 7.4 3.7 10.5 3.2 8.7 11.5 16.5 4.9 7.5 10.1 5.7 10.4 7.9 7.2 8.9 7.2 6.0 4.8 7.4 7.1 18.1 16.5 8.6 5.0 9.0 9.4 14.9 13.8 12.0 7.0 7.7 16.0 7.8 8.4 8.5 7.1 6.9 6.3 4.7 6.2 4.6 6.3 4.0 6.7 8.6 8.9 4.6 18.0 4.0 5.9 6.3 5.5 3.3 1.3 1.8 0.4 6.1 6.3 2.0 7.2 8.8 5.5 10.7 14.7 7.6 6.9 3.7 14.7 8.8 13.2 17.9 5.1 10.0 5.4 5.3 9.1 15.8 8.5 8.5 2.3 8.0 5.0 4.4 11.6 8.0 6.4 8.9 5.7 6.4 12.4 12.9 3.7 9.6 7.2 7.8 4.7 12.5 4.6 6.4 11.2 12.3 7.6 15.8 4.6 7.7 11.0 6.2 12.1 5.0 4.5 6.6 3.1 3.5 5.4 7.3 3.2 5.5 12.8 11.8 10.0 7.4 5.1 5.3 1.3 0.4 1.8 6.3 0.3 5.2 1.8 3.1 5.1 1.3 3.3 4.5 5.0 1.3 6.1 0.2 0.8 0.9 2.0 7.4 10.5 11.5 16.5 7.4 7.1 9.0 9.4 16.0 8.9 PDPK1 PDK1 ENSG00000140992 "3-phosphoinositide dependent protein kinase 1" O15530 16 2537964-2603188 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004272, HPA035199, HPA068961" Supported Approved Vesicles Vesicles "CAB004272: AB_626657, HPA035199: , HPA068961: " "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (3.12e-3)" "unprognostic (4.21e-2)" "unprognostic (1.34e-1)" "unprognostic (4.69e-3)" "unprognostic (8.37e-2)" "unprognostic (3.18e-2)" "unprognostic (8.17e-2)" "unprognostic (3.70e-2)" "unprognostic (1.52e-2)" "unprognostic (3.28e-2)" "prognostic favourable (1.29e-14)" "unprognostic (2.04e-2)" "unprognostic (5.96e-2)" "unprognostic (1.95e-1)" "unprognostic (2.16e-1)" 11.1 14.9 21.0 11.6 31.9 14.2 14.2 29.6 26.4 10.5 15.6 14.5 10.4 17.2 13.0 14.0 13.8 15.3 10.8 14.8 17.2 13.5 17.6 12.6 13.4 13.5 11.3 20.6 14.8 28.2 34.5 13.9 17.1 16.7 13.6 15.3 12.8 16.5 13.2 18.2 14.1 19.1 12.9 10.9 13.7 13.4 14.2 10.1 14.1 16.1 10.6 13.9 12.3 13.3 5.1 9.1 14.7 9.4 5.4 6.0 4.5 8.4 10.8 13.5 9.0 14.0 11.7 14.3 14.0 9.1 12.6 10.6 10.8 10.1 13.9 9.6 13.6 13.4 16.1 10.1 12.0 24.7 10.9 7.3 14.3 17.9 12.2 12.1 19.4 10.6 18.6 13.5 9.1 11.5 13.6 11.3 14.7 17.8 12.2 8.5 8.5 9.7 25.0 13.5 12.5 12.2 7.5 21.3 11.0 18.2 21.0 7.5 19.4 15.3 14.1 13.8 13.7 13.4 12.1 15.1 14.3 21.7 6.6 8.4 11.9 3.9 7.9 9.0 5.1 9.3 4.8 5.1 4.7 6.0 6.7 4.5 5.3 4.9 14.7 5.4 9.4 9.1 2.3 4.5 21.0 31.9 29.6 26.4 17.2 13.5 11.3 20.6 16.7 10.1 PDSS1 "COQ1, TPRT, TPT" ENSG00000148459 "Decaprenyl diphosphate synthase subunit 1" Q5T2R2 10 26697659-26746798 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 22.4;lymphoid tissue: 31.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038032, HPA042741" Uncertain Approved Cytosol Cytosol "HPA038032: AB_10670650, HPA042741: " "unprognostic (1.41e-2)" "unprognostic (3.92e-1)" "unprognostic (8.92e-3)" "prognostic unfavourable (1.66e-4)" "unprognostic (6.79e-3)" "unprognostic (5.43e-2)" "prognostic unfavourable (1.25e-5)" "unprognostic (2.47e-2)" "unprognostic (9.43e-2)" "unprognostic (2.33e-2)" "unprognostic (2.20e-1)" "unprognostic (4.11e-2)" "unprognostic (2.99e-3)" "unprognostic (2.93e-3)" "unprognostic (8.85e-2)" "unprognostic (9.83e-2)" "unprognostic (6.36e-2)" 3.1 2.6 2.4 7.0 3.1 5.6 3.5 5.6 5.1 3.1 18.2 1.5 1.2 20.6 3.8 2.1 8.3 3.4 3.7 4.2 2.2 2.2 8.6 7.2 4.0 7.8 2.1 2.3 2.8 3.8 1.7 2.5 2.8 2.9 2.3 17.0 3.2 3.5 1.8 10.4 2.7 22.4 3.6 3.1 5.7 3.8 3.0 1.6 31.8 2.1 4.7 5.0 2.9 4.0 3.2 5.2 0.9 5.3 0.8 3.4 1.3 7.5 5.9 4.5 8.2 1.5 2.8 6.2 7.0 1.8 10.2 7.0 9.0 4.2 17.3 3.7 3.4 9.6 14.3 10.7 8.7 7.2 12.0 14.9 5.1 6.5 2.2 9.9 5.9 3.5 4.6 9.5 2.5 5.3 13.7 4.6 7.1 11.9 31.2 7.0 9.0 5.7 14.5 12.9 12.5 6.0 3.6 13.2 8.1 6.8 14.0 7.6 4.9 11.6 3.4 5.7 9.1 11.7 11.1 1.8 6.7 12.6 5.6 25.2 4.4 0.0 5.3 0.9 0.9 4.1 2.1 0.5 1.8 1.3 5.2 3.2 3.4 1.5 0.3 0.8 2.1 1.4 0.1 1.3 2.4 3.1 5.6 5.1 2.2 2.2 2.1 2.3 2.9 1.6 PDSS2 "bA59I9.3, C6orf210" ENSG00000164494 "Decaprenyl diphosphate synthase subunit 2" Q86YH6 6 107152557-107459564 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Cancer-related genes, Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029685, HPA029686" Approved Enhanced Cytosol Cytosol "HPA029685: AB_10600219, HPA029686: AB_10602309" "prognostic unfavourable (1.34e-5)" "unprognostic (1.44e-1)" "prognostic favourable (5.74e-5)" "unprognostic (5.76e-2)" "unprognostic (1.42e-1)" "unprognostic (3.30e-2)" "unprognostic (3.26e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (1.18e-1)" "unprognostic (9.38e-2)" "unprognostic (2.19e-1)" "prognostic favourable (3.75e-7)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" 10.6 27.3 7.2 17.0 8.3 8.3 19.6 9.0 10.3 10.4 12.7 9.0 13.7 9.6 13.1 11.4 11.5 9.2 11.2 16.0 7.0 6.8 22.1 27.4 18.2 18.3 9.2 5.3 10.8 14.0 11.4 19.4 7.0 9.6 15.6 13.9 12.0 19.9 19.9 13.1 9.0 10.1 11.0 8.1 9.1 10.5 12.8 10.1 11.3 14.1 11.1 10.6 10.9 12.9 8.5 9.4 4.1 12.1 4.6 8.3 4.3 5.6 7.6 6.5 10.1 11.3 14.5 15.0 10.0 12.7 9.6 9.3 7.5 8.2 10.8 9.2 11.1 7.8 15.7 12.5 13.2 6.9 7.7 10.7 9.0 12.5 12.0 13.8 8.7 10.7 14.9 15.2 12.1 10.1 15.2 14.7 9.4 7.0 4.0 14.6 4.1 9.9 7.2 5.8 8.7 11.9 7.8 6.4 5.6 6.8 12.0 14.3 9.8 16.7 6.3 6.9 4.1 9.6 8.5 4.1 5.0 8.4 12.8 20.6 12.6 4.1 6.6 3.5 5.3 7.6 8.3 6.6 5.6 6.8 9.4 8.5 7.3 6.9 0.9 4.6 12.1 4.5 7.1 4.3 7.2 8.3 9.0 10.3 7.0 6.8 9.2 5.3 9.6 10.1 PDXK "C21orf124, C21orf97, FLJ21324, FLJ31940, MGC15873, PKH, PNK, PRED79" ENSG00000160209 "Pyridoxal kinase" O00764 21 43719094-43762307 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 68.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030196, HPA030197, HPA030198, CAB033918" Enhanced Enhanced Nucleoplasm 870000 Nucleoplasm "CAB033918: AB_2162502, HPA030196: AB_10599735, HPA030197: AB_10601792, HPA030198: AB_10603570" "unprognostic (1.01e-1)" "unprognostic (1.99e-1)" "unprognostic (5.88e-2)" "unprognostic (1.87e-1)" "unprognostic (8.29e-2)" "unprognostic (4.31e-3)" "unprognostic (3.64e-3)" "unprognostic (1.32e-1)" "unprognostic (8.66e-2)" "unprognostic (9.34e-2)" "unprognostic (2.10e-1)" "unprognostic (3.54e-1)" "unprognostic (3.70e-2)" "unprognostic (1.31e-3)" "unprognostic (1.10e-1)" "unprognostic (4.78e-2)" "unprognostic (1.51e-3)" 28.1 13.2 37.4 8.7 36.6 13.3 13.3 21.9 38.5 9.7 13.8 11.0 15.7 16.7 9.0 13.2 11.0 12.9 8.8 11.4 26.1 30.4 22.8 17.4 20.4 9.5 24.1 22.7 16.4 17.6 25.7 20.7 12.6 20.3 10.6 11.8 7.8 18.3 13.9 5.8 14.3 22.1 8.8 10.1 7.8 15.2 68.9 10.7 3.9 13.6 7.0 11.0 9.7 8.6 2.7 2.5 1.3 7.7 1.9 3.3 2.4 17.2 21.2 3.4 6.4 8.3 11.8 4.1 6.2 9.8 6.1 5.1 17.2 27.1 5.8 6.7 8.9 13.1 6.5 17.8 4.0 6.5 5.6 5.9 23.2 12.7 16.4 5.5 8.7 16.7 17.0 6.4 7.1 2.8 10.3 13.5 5.7 11.7 0.8 10.1 9.2 8.1 6.6 2.0 16.2 26.3 21.2 3.3 3.9 25.9 24.0 9.2 7.9 7.8 5.1 4.4 8.7 5.9 5.8 8.2 3.8 3.4 18.3 16.1 4.3 1.3 4.8 0.2 1.7 4.4 3.3 1.4 1.7 1.9 2.5 2.7 2.0 1.4 1.3 1.9 7.7 1.2 1.5 2.4 37.4 36.6 21.9 38.5 26.1 30.4 24.1 22.7 20.3 10.7 PDXP "CIN, dJ37E16.5, FLJ32703" ENSG00000241360 "Pyridoxal phosphatase" Q96GD0 22 37658727-37666934 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.4;liver: 34.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 8 "plasmacytoid DC: 12.9" "Lineage enriched" "Detected in many" 8 "dendritic cells: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000531 Approved 17000 "HPA000531: " "unprognostic (6.29e-2)" "unprognostic (7.89e-3)" "unprognostic (1.00e-1)" "unprognostic (2.89e-1)" "unprognostic (2.15e-2)" "unprognostic (3.25e-2)" "unprognostic (2.81e-1)" "unprognostic (4.44e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (1.57e-3)" "unprognostic (2.76e-2)" "unprognostic (1.77e-1)" "unprognostic (3.03e-3)" "unprognostic (2.04e-1)" "unprognostic (4.66e-2)" "unprognostic (2.38e-1)" 2.4 14.8 43.5 1.7 32.0 3.0 2.5 24.9 55.4 1.7 8.3 5.3 0.8 15.4 3.7 4.1 1.0 3.4 2.7 12.9 38.1 27.7 10.2 34.7 1.3 3.9 16.4 15.8 3.5 8.4 6.1 7.9 1.0 13.6 3.3 7.6 3.8 7.1 4.2 5.7 0.9 15.8 4.8 9.1 2.6 3.3 10.4 4.6 4.2 3.4 1.0 5.4 2.2 0.7 1.5 12.9 0.5 0.4 0.8 0.9 0.1 2.8 6.7 14.0 12.2 4.4 1.1 1.7 6.6 3.1 12.0 9.4 2.5 0.2 18.2 6.8 3.2 1.4 18.9 0.1 10.3 5.5 37.5 3.1 9.6 13.6 2.8 12.4 15.3 0.4 1.2 5.8 8.6 5.5 11.1 11.0 10.7 2.3 25.4 20.8 7.1 16.5 19.8 10.1 13.4 5.2 0.3 32.6 20.6 6.3 5.3 11.6 1.3 9.9 3.2 10.4 13.0 11.0 13.2 11.4 14.5 19.4 9.8 4.0 13.1 0.0 0.3 0.5 0.9 0.4 0.1 1.5 0.3 0.6 0.6 1.4 0.3 0.1 0.4 0.8 0.2 12.9 0.3 0.1 43.5 32.0 24.9 50.6 38.1 27.7 16.4 15.8 13.6 4.6 PDZRN3 "KIAA1095, LNX3, SEMACAP3" ENSG00000121440 "PDZ domain containing ring finger 3" Q9UPQ7 3 73382433-73624940 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 15.1;ASC diff: 27.5;ASC TERT1: 14.5;BJ hTERT+: 19.6;HSkMC: 20.1;U-87 MG: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 52 "plasmacytoid DC: 5.2" "Lineage enriched" "Detected in single" 52 "dendritic cells: 5.2" "Group enriched" "Detected in many" 5 "amygdala: 12.4;basal ganglia: 7.4;cerebral cortex: 17.9;hippocampal formation: 14.5" "Low region specificity" "Detected in many" HPA038822 Approved "HPA038822: AB_10675952" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-2)" "prognostic favourable (3.35e-5)" "unprognostic (1.09e-1)" "unprognostic (5.54e-2)" "unprognostic (8.47e-2)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "prognostic favourable (4.93e-4)" "unprognostic (8.38e-2)" "prognostic favourable (3.65e-7)" "unprognostic (8.63e-3)" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (2.86e-3)" 13.0 17.4 11.5 4.8 12.9 0.0 10.3 1.7 26.8 18.7 32.6 4.5 4.6 4.3 29.0 12.4 13.6 11.6 13.1 19.8 9.1 2.5 5.3 0.9 6.3 1.9 3.6 11.2 35.1 2.9 0.3 2.2 8.1 6.8 15.4 6.9 9.7 9.7 14.9 38.3 7.5 10.2 26.3 3.8 1.0 19.3 3.4 2.9 0.2 1.6 5.1 1.1 21.3 18.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 27.5 14.5 0.0 7.8 19.6 2.4 1.5 7.4 0.0 0.0 0.0 10.5 0.0 0.0 0.0 2.3 0.0 1.0 0.0 0.0 0.0 4.6 0.0 0.0 20.1 0.0 6.5 0.0 0.0 0.0 0.0 2.3 0.9 0.0 0.1 2.1 0.0 0.0 4.0 0.0 0.0 0.0 1.7 5.0 0.0 3.6 5.6 2.1 0.0 0.0 9.9 0.7 11.1 1.0 0.3 0.0 0.1 14.5 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 11.5 12.9 1.7 26.8 9.1 2.5 3.6 11.2 6.8 2.9 PEAK1 "KIAA2002, sgk269" ENSG00000173517 "Pseudopodium enriched atypical kinase 1" Q9H792 15 77100656-77420144 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 5.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026313, HPA026517" Approved "HPA026313: AB_1856801, HPA026517: AB_1856802" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "unprognostic (1.05e-1)" "unprognostic (4.20e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (6.63e-3)" "unprognostic (1.90e-1)" "unprognostic (2.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.06e-1)" "unprognostic (9.75e-2)" "unprognostic (2.25e-3)" "unprognostic (5.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.33e-1)" "unprognostic (5.65e-3)" 21.5 6.0 14.3 8.7 13.2 9.7 12.4 8.4 14.1 15.1 9.3 12.3 6.2 7.2 16.1 8.7 6.6 7.5 12.2 18.5 12.3 7.5 6.6 4.9 20.5 7.5 13.8 8.8 9.8 5.8 7.6 4.2 19.5 9.8 8.4 10.2 13.7 7.0 9.5 8.8 8.4 9.1 14.8 10.1 41.8 6.7 11.5 15.9 2.7 8.3 9.0 5.7 10.0 12.2 0.9 0.6 1.1 0.6 5.5 1.4 0.4 2.5 3.8 9.0 2.1 17.0 18.4 3.1 14.0 9.7 7.4 7.5 3.0 2.3 2.0 2.5 20.1 1.2 7.2 2.2 8.5 2.0 3.7 3.6 5.7 1.8 6.2 2.1 1.9 14.1 2.2 14.4 2.4 20.8 4.7 2.0 7.9 1.0 1.2 2.3 4.1 1.0 2.5 5.4 1.4 2.2 4.6 2.0 2.4 5.4 1.1 9.4 0.8 1.5 25.4 15.9 7.6 6.6 5.9 3.1 4.4 2.8 2.7 5.1 8.5 0.4 0.6 1.1 0.7 0.2 1.4 0.9 0.2 0.2 0.3 0.8 0.3 0.3 0.6 5.5 0.2 0.6 0.2 0.4 14.3 13.2 8.4 14.1 12.3 7.5 13.8 8.8 9.8 15.9 PECR "HSA250303, SDR29C1, TERP" ENSG00000115425 "Peroxisomal trans-2-enoyl-CoA reductase" Q9BY49 2 215996329-216082955 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 78.4" "Cell line enhanced" "Detected in many" "Hep G2: 24.2;RPTEC TERT1: 23.3" "Cancer enhanced" "Detected in all" "liver cancer: 30.4" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021593, HPA022539" Enhanced Supported Peroxisomes Peroxisomes "HPA021593: AB_1855177, HPA022539: AB_1855178" "unprognostic (7.97e-2)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (2.90e-1)" "unprognostic (6.40e-2)" "unprognostic (1.16e-3)" "unprognostic (3.56e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-3)" "unprognostic (5.61e-2)" "prognostic favourable (1.36e-5)" "unprognostic (6.63e-2)" "unprognostic (1.84e-2)" "unprognostic (7.75e-2)" "unprognostic (6.64e-2)" 14.2 4.4 3.2 6.5 3.3 3.5 7.0 6.7 3.7 2.8 11.5 4.4 2.7 13.2 2.0 6.6 2.4 4.5 7.2 2.7 3.3 3.1 17.4 78.4 3.6 3.8 4.4 2.9 3.2 3.1 3.8 5.4 0.9 3.5 3.1 4.2 6.2 3.5 3.5 3.4 3.3 20.9 3.2 5.1 2.8 2.6 0.9 3.6 2.4 8.5 2.0 3.5 2.2 4.1 5.1 1.4 4.1 3.9 8.8 14.7 4.1 3.8 4.2 1.7 0.1 10.4 3.9 2.1 0.9 2.1 2.5 4.1 4.8 11.0 0.1 7.9 2.2 0.9 4.7 5.6 4.3 6.0 5.0 4.9 2.4 24.2 10.5 1.3 3.4 3.3 3.9 2.5 3.6 2.4 2.0 5.6 5.3 2.7 1.5 1.3 3.1 3.2 3.3 3.3 0.5 23.3 0.6 2.4 3.4 2.3 4.8 9.5 5.7 4.1 0.0 1.6 1.7 4.0 2.7 6.5 5.5 1.9 3.5 1.8 3.6 0.8 3.9 1.3 6.4 1.5 7.3 4.2 8.6 7.3 1.4 5.1 9.2 6.0 4.1 8.8 2.0 0.2 14.7 4.1 3.2 3.3 6.7 3.7 3.3 3.1 4.4 2.9 3.5 3.6 PELI1 ENSG00000197329 "Pellino E3 ubiquitin protein ligase 1" Q96FA3 2 64092652-64144454 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 105.7" "Cell line enhanced" "Detected in many" "CACO-2: 21.3;U-698: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 33.9" "Group enriched" "Detected in all" 4 "granulocytes: 33.9;monocytes: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: " "unprognostic (3.33e-2)" "unprognostic (3.43e-2)" "unprognostic (1.79e-2)" "prognostic unfavourable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (3.12e-3)" "unprognostic (6.73e-3)" "unprognostic (8.01e-3)" "unprognostic (4.16e-2)" "unprognostic (3.52e-3)" "unprognostic (5.99e-3)" "unprognostic (3.33e-1)" "prognostic unfavourable (5.67e-6)" "unprognostic (6.72e-2)" "unprognostic (6.22e-2)" "unprognostic (8.88e-2)" "unprognostic (1.03e-1)" 15.7 5.1 10.0 15.1 20.5 105.7 22.3 15.1 8.9 9.9 14.5 11.0 3.3 9.9 14.5 7.1 26.4 8.0 14.9 11.6 11.3 6.8 6.7 8.6 20.1 16.8 15.6 5.2 4.8 6.2 11.0 14.8 13.7 10.8 7.6 11.8 6.0 12.3 8.5 4.5 17.5 17.3 8.4 15.0 17.8 10.2 7.8 12.8 19.9 6.3 10.2 19.3 14.1 14.8 3.9 2.3 33.9 9.2 1.3 5.0 2.5 1.2 1.0 13.7 9.1 1.6 1.2 3.1 1.7 2.0 1.6 2.6 21.3 1.5 17.5 4.3 0.6 2.1 4.1 3.8 3.2 4.3 3.3 1.6 0.6 3.4 4.8 1.7 3.1 1.6 3.0 2.4 8.2 9.0 0.9 4.4 1.3 0.1 3.7 2.5 8.9 0.6 4.7 4.7 9.9 6.6 3.9 6.3 8.8 1.3 2.0 4.7 1.1 1.2 6.4 1.5 2.2 1.5 2.5 10.1 0.9 53.0 0.8 1.5 4.0 5.1 6.5 6.3 0.4 6.1 0.7 3.9 2.2 0.9 2.3 2.4 2.7 1.1 33.9 1.3 9.2 0.2 5.0 2.5 10.0 20.5 15.1 8.8 11.3 6.8 15.6 5.2 10.8 12.8 PELI2 ENSG00000139946 "Pellino E3 ubiquitin protein ligase family member 2" Q9HAT8 14 56117814-56301526 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 20.7;MOLT-4: 23.2;REH: 11.4;SCLC-21H: 10.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebellum: 21.4" "Cell type enhanced" "Detected in many" "neutrophil: 9.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: " "unprognostic (3.26e-1)" "unprognostic (2.25e-1)" "unprognostic (9.21e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (2.53e-2)" "unprognostic (3.36e-3)" "unprognostic (1.81e-1)" "unprognostic (2.68e-2)" "unprognostic (1.18e-1)" "unprognostic (2.14e-1)" "prognostic favourable (1.53e-6)" "unprognostic (3.64e-1)" "unprognostic (2.15e-1)" "unprognostic (5.43e-2)" "unprognostic (2.22e-1)" 12.3 3.3 5.2 5.6 4.6 16.5 8.7 21.4 6.5 7.5 9.4 5.4 9.7 11.1 9.3 7.1 4.7 5.9 11.5 3.4 4.6 4.5 9.7 3.1 7.3 4.8 5.2 3.9 16.0 38.9 1.7 5.5 3.3 4.4 8.2 4.2 9.2 7.6 12.4 3.8 6.5 12.6 17.7 5.8 6.6 14.1 10.0 4.2 38.2 4.9 3.4 2.6 13.3 14.9 0.9 2.0 9.0 3.0 0.5 0.8 1.1 0.0 1.9 5.5 0.0 3.1 4.6 0.1 0.7 2.5 0.5 0.0 0.1 0.4 0.1 2.6 1.5 0.5 4.2 0.0 0.2 1.3 1.5 4.7 8.5 0.0 2.6 0.7 20.7 2.9 0.2 0.0 0.0 1.0 3.5 0.1 0.6 0.0 23.2 0.2 9.0 0.7 11.4 0.3 1.0 2.2 9.3 10.9 0.0 0.5 0.0 6.1 0.0 3.8 0.3 1.6 2.8 0.5 2.6 0.4 0.0 0.6 2.9 3.2 1.6 1.4 3.0 3.5 0.5 1.6 0.8 0.2 0.6 0.3 2.0 0.9 0.4 0.3 9.0 0.5 1.2 0.5 0.0 1.1 5.2 4.6 21.4 4.4 4.6 4.5 5.2 3.9 4.4 4.2 PELI3 MGC35521 ENSG00000174516 "Pellino E3 ubiquitin protein ligase family member 3" Q8N2H9 11 66466327-66477337 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033750, HPA038875, HPA062281" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles "Nucleoplasm, Vesicles" Nucleoli "CAB033750: AB_2161361, HPA038875: , HPA062281: " "unprognostic (1.15e-1)" "unprognostic (1.58e-1)" "unprognostic (3.04e-1)" "unprognostic (1.43e-1)" "unprognostic (1.02e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-2)" "unprognostic (1.94e-1)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.19e-3)" "unprognostic (7.91e-3)" "prognostic favourable (8.19e-4)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (3.01e-2)" 6.7 9.5 14.5 3.8 17.0 1.8 7.4 19.6 33.1 7.4 8.3 6.7 6.4 4.8 10.3 9.1 10.6 8.2 10.1 7.7 17.4 13.5 4.6 3.2 7.1 4.3 13.0 12.5 15.3 9.9 21.5 8.3 3.8 15.8 11.5 2.9 6.4 10.4 22.3 10.8 11.2 4.7 11.3 6.2 5.0 5.8 6.2 7.8 0.3 8.5 2.7 3.4 9.0 11.8 3.3 3.3 1.3 6.8 1.2 3.1 1.4 15.3 6.5 5.3 4.1 8.5 3.3 4.2 4.9 6.4 4.7 4.0 9.5 3.5 3.8 4.9 5.4 8.2 3.5 6.2 1.9 7.5 3.0 1.0 5.4 2.8 5.4 0.8 7.5 3.1 7.0 4.8 1.7 0.9 1.8 6.1 2.0 9.4 3.1 2.4 3.3 6.7 10.7 3.9 4.0 2.6 4.9 6.4 3.5 2.5 7.1 16.7 8.3 4.2 2.7 4.2 6.4 18.1 4.1 5.6 3.2 2.0 8.7 2.5 3.4 1.3 2.5 0.4 2.5 1.8 2.0 2.8 2.1 3.1 3.3 3.3 2.2 1.8 0.1 1.2 6.8 1.0 2.4 1.4 14.5 17.0 19.6 33.1 17.4 13.5 13.0 12.5 15.8 7.8 PEMT "PEMPT, PEMT2" ENSG00000133027 "Phosphatidylethanolamine N-methyltransferase" Q9UBM1 17 17505563-17591708 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 95.7;liver: 103.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042375 Approved Approved Cytosol Cytosol "HPA042375: AB_10796905" "unprognostic (1.39e-2)" "unprognostic (3.43e-1)" "unprognostic (2.43e-2)" "prognostic favourable (6.77e-6)" "unprognostic (2.85e-1)" "unprognostic (7.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (3.41e-2)" "unprognostic (5.47e-3)" "unprognostic (2.67e-1)" "unprognostic (8.63e-3)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (6.66e-2)" "unprognostic (7.60e-2)" 21.8 7.5 5.6 2.8 6.2 4.2 26.5 2.9 8.1 16.1 6.1 6.4 13.2 7.4 8.7 95.7 5.6 10.5 4.7 5.3 5.3 6.1 8.5 103.5 5.5 6.7 6.3 4.8 7.7 11.4 4.4 5.7 7.1 6.2 7.3 2.2 7.3 12.7 12.9 7.4 7.3 5.8 4.0 6.4 2.8 4.6 19.1 3.2 3.8 9.9 6.3 5.4 3.9 5.2 12.8 17.0 1.6 23.4 15.1 14.4 11.6 14.3 27.5 7.2 19.0 15.5 10.9 10.9 9.2 8.2 12.6 10.0 16.0 9.8 12.6 16.8 9.4 17.1 10.7 5.5 3.2 9.3 37.3 6.2 15.1 23.0 17.1 5.6 9.4 11.1 11.6 8.4 12.8 6.7 6.0 5.3 5.6 27.5 9.9 10.0 10.2 22.6 9.3 11.7 11.5 10.4 5.3 7.3 17.3 6.5 4.4 16.4 6.8 2.1 5.9 12.4 12.5 20.7 8.0 7.4 4.9 2.3 11.5 7.8 10.2 1.0 23.4 1.1 10.1 20.8 14.4 12.6 13.2 12.7 17.0 12.8 10.6 11.9 1.6 15.1 14.2 15.5 12.0 11.6 5.6 6.2 2.9 8.1 5.3 6.1 6.3 4.8 6.2 3.2 PEPD ENSG00000124299 "Peptidase D" P12955 19 33386950-33521794 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Collagen degradation" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 92.9;kidney: 106.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015599, HPA072045" Enhanced Approved Nucleoplasm 1000000000 Nucleoplasm "HPA015599: AB_1855192, HPA072045: " "unprognostic (1.39e-1)" "unprognostic (2.62e-2)" "unprognostic (2.27e-1)" "unprognostic (4.01e-2)" "unprognostic (2.98e-1)" "unprognostic (6.77e-2)" "unprognostic (2.82e-1)" "unprognostic (3.64e-2)" "unprognostic (3.96e-1)" "unprognostic (5.10e-2)" "unprognostic (1.11e-2)" "unprognostic (1.99e-1)" "prognostic favourable (6.50e-9)" "unprognostic (4.38e-2)" "unprognostic (1.99e-1)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" 23.5 17.2 9.8 8.9 10.4 4.1 21.8 7.6 14.9 9.8 60.1 18.7 6.9 58.1 14.3 11.5 14.9 9.6 13.6 8.0 10.8 9.1 106.0 48.6 11.1 10.6 16.0 7.7 12.6 9.0 9.6 12.5 10.4 13.0 9.2 6.6 13.3 9.6 9.0 9.7 11.4 92.9 10.4 17.4 13.4 9.3 8.4 11.5 8.4 15.0 9.7 10.6 11.9 11.9 17.1 32.3 27.5 39.1 16.8 25.8 32.6 13.2 35.9 10.6 17.0 45.2 17.4 24.5 11.7 24.1 15.0 17.1 31.2 11.6 5.4 17.6 29.5 3.4 15.2 9.6 12.4 15.2 15.0 34.3 7.3 31.7 30.9 9.9 41.6 21.4 9.1 13.7 8.5 20.0 6.5 15.6 16.3 16.1 7.6 3.3 14.6 14.6 15.0 14.4 14.9 13.0 34.9 13.0 33.4 21.9 10.8 17.7 7.5 10.8 16.7 14.5 15.7 18.8 13.6 14.3 21.2 4.7 15.5 14.4 20.6 27.5 36.1 2.5 25.8 39.1 22.6 17.1 25.7 23.8 32.3 16.3 16.9 19.6 1.9 16.8 27.2 9.9 23.6 32.6 9.8 10.4 7.6 14.9 10.8 9.1 16.0 7.7 13.0 11.5 PFAS "FGARAT, GATD8, KIAA0361, PURL" ENSG00000178921 "Phosphoribosylformylglycinamidine synthase" O15067 17 8247618-8270491 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 28.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022140, HPA022886" Enhanced Approved Vesicles 350000 Vesicles "HPA022140: AB_1855232, HPA022886: AB_1855233" "unprognostic (1.90e-1)" "unprognostic (9.21e-2)" "unprognostic (2.12e-1)" "unprognostic (5.19e-3)" "unprognostic (2.59e-1)" "unprognostic (6.40e-2)" "prognostic unfavourable (9.19e-4)" "unprognostic (3.19e-1)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (5.47e-3)" "unprognostic (1.08e-3)" "unprognostic (9.51e-3)" "unprognostic (3.63e-2)" "unprognostic (6.57e-2)" "unprognostic (2.88e-3)" "unprognostic (3.85e-1)" 15.4 15.3 11.4 14.8 13.0 17.5 12.8 14.6 18.5 11.2 12.4 14.0 10.0 9.8 15.1 11.2 13.2 13.5 14.3 9.7 9.0 8.0 13.0 17.0 9.5 18.5 10.7 12.6 16.6 15.7 11.5 9.2 10.7 10.7 11.5 12.2 12.0 10.6 10.6 11.6 13.6 11.5 14.3 7.9 18.0 11.4 17.2 11.1 29.5 12.8 10.8 16.2 10.4 9.5 9.2 7.1 28.2 2.9 2.7 6.5 1.1 5.9 26.3 13.5 20.2 4.9 4.1 15.6 7.6 2.9 14.1 10.7 12.8 5.4 26.3 12.4 4.5 13.9 31.1 10.0 10.5 11.9 25.4 15.4 24.8 15.9 4.3 12.4 11.5 3.8 2.4 16.3 10.3 11.7 20.6 4.0 5.6 8.9 22.0 10.8 22.5 12.0 33.1 14.0 12.6 6.5 9.9 8.2 12.8 9.5 6.1 8.7 6.0 5.7 8.1 7.9 10.2 14.3 18.8 4.7 8.5 12.9 8.7 17.7 13.2 9.1 2.9 6.5 4.0 2.5 5.2 7.8 5.2 4.6 2.4 9.2 6.5 5.1 28.2 2.7 1.9 7.1 2.7 1.1 11.4 13.0 14.6 18.5 9.0 8.0 10.7 12.6 10.7 11.1 PFKFB2 ENSG00000123836 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" O60825 1 207034366-207081024 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 13.9;plasmacytoid DC: 16.7" "Group enriched" "Detected in many" 8 "dendritic cells: 16.7;granulocytes: 13.9" "Low region specificity" "Detected in all" "HPA049975, HPA063575" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA049975: , HPA063575: " "unprognostic (1.30e-1)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.75e-2)" "unprognostic (2.27e-1)" "unprognostic (3.76e-2)" "unprognostic (9.96e-3)" "unprognostic (9.74e-2)" "unprognostic (7.27e-2)" "unprognostic (2.27e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" "prognostic favourable (3.23e-7)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" "prognostic unfavourable (8.63e-4)" "unprognostic (1.86e-2)" 3.3 6.1 9.8 5.8 16.6 15.7 5.1 2.1 14.6 7.3 16.0 19.5 5.3 23.2 4.0 9.1 7.7 4.5 9.1 22.8 14.1 7.7 22.0 3.6 10.9 5.3 13.4 15.1 4.3 11.9 6.2 27.5 3.0 25.3 3.9 18.1 22.4 6.3 3.5 34.9 6.4 18.7 4.0 17.4 12.5 10.7 6.1 15.1 6.5 38.4 8.8 5.0 3.4 3.6 1.6 16.7 13.9 1.9 1.1 0.4 0.4 9.5 4.2 2.8 4.8 5.7 2.8 4.6 1.3 1.7 2.4 1.3 10.2 13.8 1.7 2.2 2.1 13.6 2.0 5.1 1.4 0.3 2.1 13.5 10.6 3.8 4.8 0.0 9.5 4.1 7.8 2.3 12.9 0.5 9.2 0.1 1.3 2.9 2.3 0.4 3.8 6.4 0.0 0.0 0.2 3.3 9.9 4.4 2.7 8.9 15.1 11.2 10.3 1.1 0.2 0.0 5.2 7.3 1.2 4.4 4.4 0.9 5.9 0.0 2.6 1.0 0.9 13.9 0.2 1.9 0.3 1.3 0.1 0.3 0.8 1.6 0.3 0.4 2.6 1.1 1.3 16.7 0.0 0.4 9.8 16.6 2.1 14.6 14.1 7.7 13.4 15.1 25.3 15.1 PFKFB3 ENSG00000170525 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" Q16875 10 6144934-6254644 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 105.6;skeletal muscle: 135.7" "Cell line enhanced" "Detected in many" "A549: 71.1;RPTEC TERT1: 44.9;T-47d: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 20.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008266, CAB020795, HPA043889" Uncertain Enhanced Nucleoplasm Nucleoplasm "CAB020795: , HPA008266: AB_1855239, HPA043889: " "unprognostic (1.61e-1)" "unprognostic (5.08e-3)" "unprognostic (2.89e-2)" "unprognostic (6.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (1.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (3.30e-2)" "unprognostic (7.34e-2)" "prognostic unfavourable (1.87e-7)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" 105.6 9.0 16.4 25.7 17.9 77.0 43.4 8.5 29.4 6.6 8.8 29.1 10.6 7.4 9.4 6.3 13.0 14.4 22.4 5.7 16.6 13.2 22.1 11.2 15.1 12.1 19.2 12.9 8.0 8.1 4.0 10.2 7.5 20.7 5.4 3.8 19.3 9.1 20.0 135.7 11.8 6.9 6.5 36.0 12.4 6.7 4.6 16.8 3.3 2.9 4.7 10.3 10.3 10.1 1.5 3.6 20.5 7.1 0.8 4.7 2.9 5.1 71.1 5.6 4.5 21.4 2.7 3.0 7.6 5.4 5.6 8.8 3.3 18.8 8.8 5.0 3.3 16.6 6.0 12.0 6.5 10.4 4.2 5.2 3.6 1.2 1.8 5.0 7.9 1.9 4.0 9.7 2.3 10.9 3.8 3.3 4.5 8.4 3.5 4.7 5.5 5.0 8.0 2.7 3.4 44.9 2.6 5.4 2.2 5.5 6.0 10.8 46.8 6.0 13.7 5.9 5.4 0.7 9.1 6.8 2.3 8.0 16.3 5.9 9.0 2.2 5.6 5.5 1.8 7.1 4.7 1.5 3.4 2.3 3.6 1.4 2.5 2.4 20.5 0.8 4.1 2.2 3.2 2.9 16.4 17.9 8.5 16.9 16.6 13.2 19.2 12.9 20.7 16.8 PFKFB4 ENSG00000114268 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4" Q16877 3 48517684-48562015 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.0" "Cell line enhanced" "Detected in many" "U-87 MG: 37.1;WM-115: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.5;eosinophil: 11.4;intermediate monocyte: 7.3;neutrophil: 21.6;non-classical monocyte: 12.2" "Group enriched" "Detected in many" 6 "granulocytes: 21.6;monocytes: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047719, HPA066058" Uncertain Approved Nucleoli Nucleoli "HPA047719: , HPA066058: " "unprognostic (7.60e-2)" "prognostic unfavourable (3.04e-4)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (3.90e-3)" "unprognostic (7.96e-2)" "unprognostic (1.72e-6)" "unprognostic (1.65e-1)" "unprognostic (3.75e-2)" "unprognostic (6.78e-2)" "unprognostic (3.78e-2)" "unprognostic (7.13e-2)" "prognostic unfavourable (3.91e-8)" "unprognostic (2.04e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-3)" "unprognostic (3.35e-2)" 2.0 2.2 4.0 3.9 4.9 12.7 2.1 6.3 6.3 2.6 17.1 8.6 3.0 17.8 2.1 18.5 6.4 1.5 1.8 1.4 4.2 5.2 3.6 1.7 3.8 6.3 7.4 2.7 3.5 18.9 4.1 5.1 9.5 6.9 3.3 3.5 3.3 2.5 2.0 4.8 3.3 24.0 2.5 5.3 10.0 1.2 26.0 5.2 0.4 1.6 3.6 2.6 4.9 4.2 0.2 2.7 21.6 12.2 0.2 0.5 2.1 5.1 1.6 3.7 3.4 1.2 1.8 7.2 2.6 4.4 5.3 12.8 2.6 1.8 2.2 2.5 2.0 1.5 1.5 4.4 4.7 1.5 1.2 5.2 3.3 2.8 1.0 0.9 2.3 1.9 6.8 8.5 0.8 1.3 1.7 1.9 4.2 1.1 0.3 7.2 2.3 3.4 0.4 1.8 2.4 2.0 4.8 1.0 2.3 2.8 1.2 10.1 2.8 2.2 0.4 5.4 2.2 0.7 15.6 8.9 1.9 1.3 37.1 1.9 32.3 0.0 6.5 11.4 0.2 7.3 0.1 0.2 0.3 0.0 2.7 0.1 0.5 0.1 21.6 0.2 12.2 0.3 0.0 2.1 4.0 4.9 6.3 6.3 4.2 5.2 7.4 2.7 6.9 5.2 PFKL ENSG00000141959 "Phosphofructokinase, liver type" P17858 21 44300051-44327376 "Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030047 Approved 1800000 "HPA030047: AB_10602815" "unprognostic (6.21e-3)" "unprognostic (2.93e-1)" "unprognostic (4.46e-2)" "unprognostic (1.23e-2)" "unprognostic (1.87e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "unprognostic (6.98e-2)" "unprognostic (9.75e-2)" "prognostic unfavourable (4.41e-4)" "unprognostic (5.69e-2)" "unprognostic (5.40e-2)" "unprognostic (1.55e-1)" "unprognostic (4.99e-1)" "unprognostic (2.49e-1)" "unprognostic (8.06e-2)" "unprognostic (3.01e-2)" 32.0 16.7 28.0 26.0 29.5 26.4 23.1 21.3 46.0 28.3 38.7 40.9 30.1 65.5 21.3 33.5 33.5 22.8 37.5 18.4 28.8 23.4 40.3 31.3 21.0 25.2 32.4 33.0 19.5 27.1 12.3 17.1 31.9 29.1 20.2 17.2 36.3 28.8 28.5 8.3 31.1 59.3 20.5 36.1 28.1 42.7 24.0 29.1 16.4 20.4 15.4 26.0 27.2 23.9 20.3 26.9 5.2 38.0 7.7 25.2 22.8 32.3 14.2 10.1 29.2 15.9 11.9 44.5 24.4 15.8 14.2 14.0 19.0 7.1 19.2 29.0 16.2 17.7 8.0 22.1 3.2 16.1 18.2 38.8 12.4 31.0 12.3 29.2 24.7 15.5 13.5 14.4 7.1 20.8 23.9 22.0 9.6 41.1 12.6 22.8 15.9 15.9 31.2 9.6 52.1 6.4 35.8 17.8 13.4 35.5 30.1 15.6 23.9 25.9 30.1 21.5 13.9 14.0 9.4 42.8 11.5 7.9 35.8 23.3 17.2 5.1 22.2 5.2 12.9 37.9 10.8 14.4 17.0 11.8 26.9 20.3 10.2 7.9 4.5 7.7 38.0 17.0 25.2 22.8 28.0 29.5 21.3 46.0 28.8 23.4 32.4 33.0 29.1 29.1 PFKM "PFK-1, PFKX, PPP1R122" ENSG00000152556 "Phosphofructokinase, muscle" P08237 12 48105139-48146404 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 284.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002117 Approved Approved "Endoplasmic reticulum" 1100000 "Endoplasmic reticulum" "HPA002117: AB_1855245" "unprognostic (4.60e-2)" "unprognostic (2.56e-3)" "unprognostic (2.56e-3)" "prognostic unfavourable (5.85e-6)" "unprognostic (4.97e-1)" "prognostic unfavourable (7.91e-5)" "unprognostic (5.93e-3)" "unprognostic (1.63e-1)" "unprognostic (2.80e-1)" "unprognostic (1.86e-1)" "unprognostic (2.29e-3)" "unprognostic (6.73e-2)" "prognostic favourable (2.28e-7)" "unprognostic (1.07e-1)" "unprognostic (1.53e-1)" "unprognostic (5.72e-2)" "unprognostic (1.30e-2)" 4.4 11.6 10.0 3.0 16.2 2.3 3.9 13.0 23.6 5.8 5.3 6.1 5.4 3.0 6.4 5.8 9.1 5.4 4.8 55.5 8.2 10.1 10.9 2.7 3.6 2.4 9.4 10.8 10.8 3.0 14.2 11.4 3.3 17.9 7.1 4.2 10.8 5.2 9.4 284.3 2.6 2.8 8.3 4.6 2.7 4.1 10.3 3.8 0.0 5.5 54.9 4.6 5.3 3.7 10.7 6.7 8.7 3.2 2.2 5.4 3.5 8.7 8.5 27.0 24.6 27.6 20.1 5.5 23.7 21.8 20.5 14.6 21.0 11.0 52.2 19.7 11.5 9.8 23.4 23.9 19.3 1.2 12.2 14.9 19.4 0.7 14.8 0.7 8.6 28.4 14.1 18.0 29.7 23.3 17.8 26.4 18.9 6.6 18.3 1.2 19.3 26.5 30.9 15.8 40.1 14.0 9.7 32.0 23.5 14.0 22.3 23.7 22.5 3.2 20.9 9.5 13.2 13.9 19.7 14.4 38.4 28.6 18.4 1.5 8.0 0.4 3.2 8.7 2.5 2.8 1.0 10.7 4.3 2.4 6.7 7.0 5.4 3.0 0.8 2.2 2.3 1.0 3.8 3.5 10.0 16.2 13.0 23.6 8.2 10.1 9.4 10.8 17.9 3.8 PFKP "PFK-C, PFKF" ENSG00000067057 "Phosphofructokinase, platelet" Q01813 10 3066333-3137712 "Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018257, HPA056484" Uncertain Supported Cytosol 4500000 Cytosol "HPA018257: AB_10960391, HPA056484: " "unprognostic (1.16e-1)" "unprognostic (2.41e-3)" "unprognostic (5.79e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.55e-4)" "prognostic unfavourable (8.72e-6)" "unprognostic (1.36e-3)" "unprognostic (2.38e-1)" "unprognostic (8.51e-2)" "unprognostic (2.37e-2)" "unprognostic (8.82e-2)" "unprognostic (6.02e-3)" "unprognostic (2.60e-2)" "unprognostic (9.74e-2)" "unprognostic (2.06e-1)" "unprognostic (4.54e-3)" 14.6 7.9 29.6 22.0 28.9 9.2 8.1 34.2 61.4 9.7 20.5 11.5 7.9 26.8 19.2 11.0 36.0 12.8 19.8 62.0 29.3 32.9 20.0 2.8 9.2 18.2 22.2 29.8 9.3 8.8 1.5 16.8 8.8 21.3 20.3 19.4 14.7 13.4 36.5 24.4 16.5 31.1 34.3 21.1 11.3 20.7 71.8 14.8 9.6 19.3 11.7 13.3 26.9 15.6 8.9 12.5 16.2 4.7 14.3 20.4 8.9 47.4 66.8 4.5 0.1 4.5 9.4 58.3 29.6 10.6 30.0 36.1 70.4 50.6 5.7 23.6 21.3 38.6 22.8 46.1 31.5 16.0 17.6 20.5 32.2 3.8 10.6 8.3 34.6 4.3 10.4 31.4 15.7 57.7 5.7 0.2 33.2 37.1 28.1 8.9 7.3 23.4 22.1 7.4 22.9 32.5 18.7 12.3 10.6 21.0 17.8 26.2 14.7 13.0 69.4 20.5 11.0 61.7 32.2 32.5 29.3 20.4 52.5 15.9 12.5 16.2 4.7 1.6 15.9 2.3 12.6 8.2 15.9 14.8 8.0 8.9 6.0 9.5 0.7 14.3 0.9 12.5 20.4 8.9 29.6 28.9 34.2 51.7 29.3 32.9 22.2 29.8 21.3 14.8 PGA3 ENSG00000229859 "Pepsinogen 3, group I (pepsinogen A)" P0DJD8 11 61203307-61213098 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "stomach 1: 1048.8" "Group enriched" "Detected in some" 5 "HMC-1: 13.4;THP-1: 4.4" "Cancer enriched" "Detected in single" 498 "stomach cancer: 24.8" "Region enriched" "Detected in single" 15 "cerebral cortex: 4.8" "Cell type enhanced" "Detected in many" "intermediate monocyte: 6.7" "Lineage enriched" "Detected in many" 4 "monocytes: 6.7" "CAB026358, HPA046875" Enhanced "Secreted to digestive system" "CAB026358: , HPA046875: " "unprognostic (6.39e-2)" "unprognostic (1.11e-1)" 0.3 0.1 0.0 0.2 0.3 0.0 0.3 0.0 4.8 0.2 0.4 19.9 0.0 0.1 0.1 0.5 36.8 0.2 0.0 0.4 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.4 17.7 0.0 0.0 0.2 0.0 0.2 0.0 0.1 2.0 0.1 0.1 0.0 0.0 0.7 0.0 1.4 1048.8 0.1 0.0 0.0 0.1 3.8 0.0 0.1 0.0 0.3 0.3 1.1 6.7 0.5 1.5 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 13.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.3 0.4 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.5 4.3 0.2 1.5 6.7 0.9 0.2 0.5 1.4 0.3 0.3 0.2 1.4 1.1 0.5 1.7 0.2 0.1 3.0 0.0 0.3 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 PGA4 ENSG00000229183 "Pepsinogen 4, group I (pepsinogen A)" P0DJD7 11 61222216-61231927 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 120 "stomach 1: 924.0" "Group enriched" "Detected in some" 8 "BJ hTERT+: 17.2;THP-1: 8.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "classical monocyte: 7.6;intermediate monocyte: 5.9;non-classical monocyte: 2.1" "Lineage enriched" "Detected in single" 23 "monocytes: 7.6" HPA046875 Supported "Secreted to digestive system" "HPA046875: " "unprognostic (2.22e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 924.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 7.6 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 1.4 PGA5 ENSG00000256713 "Pepsinogen 5, group I (pepsinogen A)" P0DJD9 11 61241042-61251448 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "stomach 1: 296.9" "Cell line enriched" "Detected in some" 14 "BJ hTERT+: 25.1" "Cancer enriched" "Detected in some" 12 "stomach cancer: 15.0" "Group enriched" "Detected in some" 50 "classical monocyte: 3.4;intermediate monocyte: 7.7;non-classical monocyte: 3.7" "Lineage enriched" "Detected in single" 77 "monocytes: 7.7" HPA046875 Supported "Secreted to digestive system" "HPA046875: " "unprognostic (1.36e-3)" "unprognostic (2.98e-2)" "unprognostic (5.83e-3)" "unprognostic (2.11e-1)" "unprognostic (4.22e-1)" "unprognostic (4.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (7.10e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 296.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.6 PGAM1 "PGAM-B, PGAMA" ENSG00000171314 "Phosphoglycerate mutase 1" P18669 10 97426160-97433441 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042528, HPA060483" Approved Approved Nucleoplasm 200000000 Nucleoplasm "HPA042528: , HPA060483: " "prognostic unfavourable (2.04e-4)" "prognostic unfavourable (3.86e-4)" "unprognostic (3.64e-1)" "unprognostic (5.64e-2)" "unprognostic (1.16e-1)" "unprognostic (9.47e-3)" "unprognostic (7.60e-3)" "unprognostic (1.74e-3)" "unprognostic (3.22e-1)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "unprognostic (2.48e-2)" "unprognostic (1.48e-1)" "unprognostic (5.74e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-1)" "unprognostic (2.61e-3)" 26.5 46.1 42.8 28.9 50.3 30.2 19.0 32.6 90.0 26.5 27.6 24.9 14.2 29.8 24.3 20.6 63.5 17.7 21.2 54.1 47.4 44.9 32.7 35.7 18.5 29.5 45.7 61.1 22.9 14.3 27.8 23.2 30.8 72.4 21.9 29.2 30.4 24.5 33.7 8.4 30.0 27.4 35.6 25.7 21.7 20.3 26.1 21.0 26.6 17.4 27.0 43.7 31.0 31.9 22.5 49.7 88.0 65.3 22.8 41.2 72.8 120.6 57.4 39.7 75.6 37.6 34.7 54.1 77.4 101.2 91.0 127.0 62.3 36.1 64.0 53.1 65.7 75.8 69.0 112.5 110.4 59.2 65.9 41.3 45.1 69.6 27.8 59.1 55.3 33.9 46.1 60.4 45.1 65.8 27.0 36.3 95.5 49.9 52.8 73.0 60.8 68.9 40.2 36.4 50.7 70.3 45.8 8.6 40.6 41.6 24.9 39.7 67.7 49.9 49.4 48.8 42.9 43.0 88.8 54.7 60.3 58.4 113.4 99.0 22.5 30.4 65.3 88.0 37.0 57.2 32.7 22.5 31.8 36.6 49.7 18.8 20.7 28.9 50.3 22.8 62.8 17.6 41.2 72.8 42.8 50.3 32.6 90.0 47.4 44.9 45.7 61.1 72.4 21.0 PGAM2 PGAM-M ENSG00000164708 "Phosphoglycerate mutase 2" P15259 7 44062727-44065587 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "heart muscle: 111.6;skeletal muscle: 379.1;tongue: 119.0" "Cell line enriched" "Detected in some" 9 "SCLC-21H: 38.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 1.2;neutrophil: 1.1;plasmacytoid DC: 1.3;T-reg: 1.7" "Group enriched" "Detected in many" 4 "dendritic cells: 1.3;granulocytes: 1.2;T-cells: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA043801, HPA050314, HPA060173" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol 60000000 Nucleoplasm "Nucleoli, Cytosol" "HPA043801: , HPA050314: , HPA060173: " 1.4 0.8 2.0 0.4 2.2 0.4 0.5 6.9 2.1 0.5 0.5 3.6 0.0 0.6 0.5 9.1 6.1 0.6 0.7 111.6 2.1 3.2 0.8 0.4 0.4 0.4 4.2 1.6 0.5 0.6 0.6 1.3 0.4 2.0 1.9 0.4 2.3 7.6 0.5 379.1 0.4 0.4 0.4 3.2 0.5 0.5 16.7 1.1 4.8 1.5 119.0 4.8 0.4 0.0 0.3 1.3 1.2 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 38.1 4.2 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 1.3 1.7 0.2 2.0 2.2 6.9 2.1 2.1 3.2 4.2 1.6 2.0 1.1 PGAM4 "dJ1000K24.1, PGAM-B, PGAM1, PGAM3" ENSG00000226784 "Phosphoglycerate mutase family member 4" Q8N0Y7 X 77968874-77969638 "Enzymes, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 5.3" "Low cancer specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "HPA042528, HPA060483" Uncertain Approved Nucleoplasm Nucleoplasm "HPA042528: , HPA060483: " "unprognostic (3.10e-2)" "unprognostic (2.41e-2)" "unprognostic (5.25e-2)" "unprognostic (3.18e-2)" "unprognostic (4.37e-2)" "unprognostic (4.21e-2)" "unprognostic (7.71e-2)" "unprognostic (1.89e-2)" "unprognostic (1.78e-1)" "unprognostic (7.52e-3)" "unprognostic (3.19e-2)" "unprognostic (1.14e-1)" "unprognostic (4.20e-2)" "unprognostic (1.20e-1)" "unprognostic (4.15e-2)" "unprognostic (1.10e-1)" "unprognostic (2.76e-3)" 0.9 2.1 0.9 2.6 1.5 3.0 0.4 0.8 2.1 1.9 0.6 2.4 1.4 0.7 2.9 1.3 0.0 1.3 1.0 1.5 0.9 1.2 0.4 1.2 1.5 1.0 0.1 0.7 0.7 0.7 0.5 0.7 0.6 0.2 1.1 0.8 2.0 1.3 0.4 1.0 1.3 0.5 0.3 0.7 1.6 1.2 0.7 1.9 3.7 2.4 0.8 1.6 3.5 5.3 3.1 0.3 0.9 0.4 0.0 2.7 0.5 0.1 0.6 0.8 0.0 0.5 0.8 1.4 0.3 2.3 0.2 0.0 0.7 0.6 0.3 0.0 1.1 0.7 0.0 1.6 0.9 0.4 0.2 0.2 0.0 0.5 0.0 0.6 0.8 0.9 2.6 3.9 1.1 0.7 0.8 0.9 2.0 0.0 0.7 0.1 2.6 0.3 0.0 1.3 1.0 0.6 0.0 1.0 1.8 1.6 3.0 2.7 1.4 0.7 3.7 1.5 0.5 0.6 2.4 3.7 1.4 2.2 1.1 0.7 1.1 1.3 1.9 0.7 0.6 0.9 1.5 0.8 2.1 0.5 1.6 3.5 PGAM5 "BXLBv68, MGC5352" ENSG00000247077 "PGAM family member 5, mitochondrial serine/threonine protein phosphatase" Q96HS1 12 132710819-132722734 "Enzymes, Predicted intracellular proteins" Necrosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036978, HPA036979, CAB068215" Enhanced Supported Mitochondria "Intracellular and membrane" Mitochondria "CAB068215: , HPA036978: AB_10964347, HPA036979: AB_10960559" "unprognostic (9.57e-2)" "unprognostic (2.00e-2)" "unprognostic (3.83e-2)" "unprognostic (3.11e-2)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "prognostic unfavourable (1.13e-6)" "unprognostic (3.32e-2)" "unprognostic (1.47e-1)" "unprognostic (5.67e-2)" "unprognostic (1.23e-1)" "unprognostic (6.92e-2)" "unprognostic (6.42e-3)" "unprognostic (1.63e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (5.53e-2)" 12.2 16.5 11.7 14.3 14.0 12.5 18.6 14.6 22.1 8.4 13.9 8.3 9.9 13.6 10.4 9.9 22.0 11.5 13.4 22.6 14.2 12.1 13.9 26.3 8.5 17.6 9.9 11.8 11.9 30.2 8.1 9.6 10.3 10.4 10.1 10.4 8.5 16.0 11.4 27.4 15.2 12.0 10.2 7.5 13.0 11.7 13.6 5.1 17.6 16.3 17.4 14.5 11.6 12.9 4.0 6.7 7.7 3.1 3.3 3.7 1.4 19.1 36.9 7.9 22.2 5.6 4.5 18.5 9.9 6.1 16.7 9.4 46.0 11.1 24.8 18.3 8.5 16.8 37.0 18.6 6.8 12.2 29.1 29.7 17.3 23.9 12.7 28.1 17.4 5.5 13.7 19.4 20.9 12.1 37.2 10.3 6.5 34.7 38.1 28.1 29.9 26.2 29.2 8.8 19.8 10.8 26.6 29.0 16.3 17.1 24.1 10.6 30.4 15.6 10.4 8.5 18.5 17.0 24.0 21.5 31.5 35.6 11.0 23.1 14.2 7.7 2.4 0.7 2.5 2.5 3.7 3.6 2.9 2.8 2.0 4.0 2.9 3.6 2.0 3.3 3.1 6.7 2.0 1.4 11.7 14.0 14.6 22.1 14.2 12.1 9.9 11.8 10.4 5.1 PGC ENSG00000096088 Progastricsin P20142 6 41736711-41754109 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Digestion "Aspartyl protease, Hydrolase, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "ductus deferens: 249.6;pancreas: 798.6;stomach 1: 963.7" "Cell line enriched" "Detected in some" 13 "Hep G2: 73.2" "Cancer enhanced" "Detected in many" "stomach cancer: 1050.3" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "intermediate monocyte: 1.9" "Lineage enriched" "Detected in single" 7 "monocytes: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031717, HPA031718" Enhanced Approved Nucleoplasm "Secreted to digestive system" Nucleoplasm "HPA031717: AB_10670130, HPA031718: AB_10610148" "unprognostic (9.18e-2)" "unprognostic (1.87e-1)" "unprognostic (9.83e-2)" "unprognostic (2.27e-1)" "unprognostic (7.18e-2)" "unprognostic (2.74e-1)" "unprognostic (1.47e-1)" "unprognostic (8.50e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "unprognostic (8.74e-2)" 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.3 0.1 3.0 249.6 41.7 0.1 0.0 3.3 0.3 16.8 0.1 0.1 0.1 0.1 0.3 139.4 0.0 0.1 0.0 0.1 798.6 0.0 0.1 0.0 0.1 2.3 0.0 0.0 0.1 35.9 0.1 0.1 0.1 0.0 0.1 0.1 963.7 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.2 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 1.7 0.0 0.8 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420144 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 115.1;esophagus: 123.8" "Cell line enhanced" "Detected in all" "A549: 177.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 98.6;classical monocyte: 32.0;eosinophil: 115.1;neutrophil: 38.4" "Group enriched" "Detected in all" 5 "granulocytes: 115.1;monocytes: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Intermediate filaments,Cytosol" 59000000 "Intermediate filaments, Cytosol" "HPA031314: AB_10610278, HPA031315: AB_2673825" "unprognostic (4.65e-2)" "unprognostic (2.58e-1)" "unprognostic (8.65e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "prognostic unfavourable (3.98e-4)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (1.40e-2)" "unprognostic (4.92e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" 29.8 12.7 10.9 14.2 11.8 85.5 23.7 8.0 19.1 16.0 14.1 13.8 8.1 22.9 6.3 12.5 123.8 8.4 24.9 14.3 10.3 12.1 15.4 23.2 25.6 34.9 12.4 11.4 14.3 8.3 16.2 10.8 17.0 19.3 7.9 12.9 19.7 31.8 6.8 8.5 10.6 25.3 9.5 12.6 27.6 13.4 27.0 7.4 16.8 21.2 68.8 49.9 14.8 26.1 3.9 15.9 115.1 32.0 2.0 3.0 19.0 22.6 177.4 44.2 47.5 67.3 41.7 9.6 15.3 27.2 21.2 29.1 26.0 26.1 22.2 18.9 15.7 19.2 32.3 27.5 14.3 15.3 28.2 30.0 31.9 54.6 20.5 49.6 33.4 29.7 13.8 33.5 8.3 50.1 40.1 19.7 27.2 25.7 40.9 24.8 26.6 15.6 31.8 40.6 40.9 29.7 12.2 23.8 20.8 13.1 20.8 18.1 22.9 42.6 46.9 11.2 20.0 13.3 16.9 14.9 27.3 39.9 24.5 53.9 10.1 98.6 32.0 115.1 2.6 15.3 3.0 3.9 2.5 2.4 15.9 2.3 2.4 2.6 38.4 2.0 10.9 11.4 2.4 19.0 10.9 11.8 8.0 19.1 10.3 12.1 12.4 11.4 19.3 7.4 PGGHG "ATHL1, FLJ22635" ENSG00000142102 "Protein-glucosylgalactosylhydroxylysine glucosidase" Q32M88 11 289135-296107 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "pancreas: 148.7" "Cell line enhanced" "Detected in many" "U-266/70: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA039383, HPA058829" Uncertain Enhanced Cytosol Cytosol "HPA039383: AB_10796225, HPA058829: " "unprognostic (1.40e-3)" "unprognostic (2.18e-1)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (1.36e-2)" "unprognostic (5.83e-2)" "unprognostic (7.95e-3)" "unprognostic (2.77e-2)" "unprognostic (2.16e-2)" "unprognostic (2.14e-2)" "unprognostic (2.71e-2)" "unprognostic (3.45e-1)" "unprognostic (1.92e-3)" "unprognostic (2.85e-3)" "unprognostic (1.09e-2)" "unprognostic (1.22e-1)" "prognostic favourable (5.12e-4)" 5.6 1.8 6.0 16.7 9.3 6.3 10.5 2.9 7.7 12.7 5.6 3.3 10.4 21.1 6.9 14.9 5.6 8.4 8.3 4.4 6.3 1.7 14.8 17.0 15.7 24.6 7.6 2.5 3.5 148.7 2.6 3.6 3.4 8.0 8.5 3.0 7.1 8.9 21.8 5.6 2.4 23.2 5.2 10.1 24.2 4.7 2.3 7.5 6.3 18.0 6.4 15.4 7.3 8.7 2.3 2.5 4.9 4.2 6.9 8.5 2.7 3.4 3.7 7.0 7.7 2.8 2.5 5.3 2.7 2.2 1.6 1.4 3.2 9.8 0.0 3.5 3.3 2.1 0.6 1.2 0.2 8.3 2.6 1.6 2.4 4.2 3.6 0.2 15.1 9.4 1.0 0.6 0.4 5.3 6.5 10.5 0.8 4.9 14.3 7.6 5.4 0.6 13.5 1.4 4.8 3.7 1.2 0.0 1.6 1.0 5.1 4.7 3.7 1.9 4.9 3.3 4.7 1.0 0.3 22.8 0.6 3.6 0.5 2.7 3.8 1.5 0.9 1.2 8.5 4.2 7.2 2.1 1.3 4.7 0.6 2.3 3.1 6.1 4.9 6.9 3.2 2.5 0.2 2.7 6.0 9.3 2.9 7.7 6.3 1.7 7.6 2.5 8.0 7.5 PGGT1B "BGGI, GGTI" ENSG00000164219 "Protein geranylgeranyltransferase type I subunit beta" P53609 5 115204012-115262872 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030646 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" "Nucleoplasm, Endoplasmic reticulum" Cytosol "HPA030646: AB_10602019" "unprognostic (2.73e-2)" "unprognostic (1.67e-1)" "unprognostic (3.92e-2)" "unprognostic (7.34e-2)" "unprognostic (5.57e-2)" "unprognostic (7.56e-3)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (3.25e-2)" "unprognostic (1.33e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-1)" "unprognostic (4.38e-2)" "unprognostic (1.58e-1)" "unprognostic (3.75e-1)" "unprognostic (5.93e-3)" "unprognostic (1.15e-2)" 10.5 12.4 7.3 13.3 10.1 10.9 13.9 8.8 22.1 10.8 13.8 7.7 7.9 12.3 9.2 4.6 14.9 7.3 7.0 13.5 9.5 5.9 8.2 13.7 22.2 22.2 10.2 10.0 9.6 10.1 12.0 13.4 7.8 8.2 8.4 15.1 5.7 10.6 8.4 10.2 9.9 10.4 9.5 6.9 10.4 11.0 5.1 10.5 10.2 8.8 9.9 10.1 9.6 10.5 8.0 11.5 21.8 16.7 6.7 6.3 6.4 10.1 11.1 12.6 16.3 7.4 6.2 6.2 12.6 7.4 10.5 10.8 12.0 10.9 20.7 17.1 8.8 8.0 16.6 16.5 15.8 22.8 9.2 11.9 14.4 9.6 9.9 16.3 17.6 9.3 10.2 10.3 10.8 10.5 9.6 8.9 12.0 15.8 14.3 5.4 9.4 8.6 15.7 16.9 20.9 11.0 19.2 12.4 9.4 14.9 11.4 12.0 15.3 12.2 12.0 10.8 10.2 7.4 14.6 14.8 16.5 10.9 7.8 17.0 14.9 8.3 12.8 21.8 5.0 16.6 5.6 6.8 5.7 6.3 11.5 8.0 5.4 5.0 13.1 6.7 16.7 10.3 4.9 6.4 7.3 10.1 8.8 22.1 9.5 5.9 10.2 10.0 8.2 10.5 PGK1 ENSG00000102144 "Phosphoglycerate kinase 1" P00558 X 77910739-78129296 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010065, HPA045385, HPA073644, HPA073656" Approved 290000000 "CAB010065: AB_628116, HPA045385: , HPA073644: , HPA073656: " "prognostic unfavourable (7.05e-8)" "prognostic unfavourable (2.69e-5)" "unprognostic (1.21e-1)" "unprognostic (8.30e-2)" "unprognostic (1.10e-1)" "prognostic unfavourable (2.65e-6)" "prognostic unfavourable (2.74e-4)" "unprognostic (1.13e-2)" "unprognostic (1.27e-1)" "unprognostic (6.66e-2)" "prognostic unfavourable (8.34e-4)" "unprognostic (5.66e-2)" "unprognostic (2.99e-1)" "unprognostic (8.99e-3)" "unprognostic (3.58e-1)" "unprognostic (2.90e-2)" "unprognostic (6.57e-2)" 45.0 50.9 29.2 41.3 38.4 62.2 29.9 43.8 67.9 31.9 36.6 24.2 27.5 35.5 25.7 23.3 62.1 25.6 32.4 69.4 28.6 35.0 71.8 58.5 37.5 47.6 32.1 32.7 26.8 21.2 45.7 29.0 43.7 49.9 28.3 42.8 40.0 38.2 32.0 115.5 38.7 41.9 33.9 30.1 43.7 29.7 11.3 24.9 51.8 39.1 61.1 52.4 42.2 38.0 20.9 53.7 49.2 79.0 21.0 26.3 77.0 98.9 45.9 15.4 31.0 26.6 21.6 36.6 50.7 35.3 44.6 74.9 41.6 31.2 39.7 52.5 35.0 43.1 68.0 78.8 89.5 24.2 26.8 30.7 75.7 36.1 29.2 70.3 34.3 26.9 33.3 40.4 21.5 45.5 32.0 60.7 60.8 39.1 61.4 53.2 47.5 87.4 44.5 41.3 121.5 46.5 41.4 23.0 31.7 52.5 44.8 44.0 23.5 36.9 36.6 47.8 33.0 47.7 34.9 67.5 126.1 41.7 134.5 80.0 31.2 22.7 54.6 49.2 20.8 59.9 23.2 20.9 25.0 22.6 53.7 15.8 23.0 24.4 45.7 21.0 79.0 20.9 26.3 77.0 29.2 38.4 43.8 67.9 28.6 35.0 32.1 32.7 49.9 24.9 PGK2 "PGK-2, PGKPS" ENSG00000170950 "Phosphoglycerate kinase 2" P07205 6 49785651-49787307 "Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "testis: 70.2" "Cell line enhanced" "Detected in some" "RT4: 1.0;U-2197: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045385, HPA073644, HPA073656" Supported "HPA045385: , HPA073644: , HPA073656: " "unprognostic (8.87e-3)" "unprognostic (5.02e-1)" "unprognostic (1.24e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 70.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.1 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGLS 6PGL ENSG00000130313 6-phosphogluconolactonase O95336 19 17511629-17521288 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040744, HPA042032" Approved Supported Nucleoplasm,Cytosol 10000000 Nucleoplasm Cytosol "HPA040744: AB_2677111, HPA042032: AB_2677809" "unprognostic (3.68e-2)" "unprognostic (8.98e-3)" "unprognostic (1.25e-1)" "unprognostic (9.64e-3)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (3.55e-3)" "unprognostic (2.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (2.16e-1)" "unprognostic (1.30e-1)" "unprognostic (4.75e-3)" "unprognostic (2.39e-1)" "unprognostic (1.99e-1)" "unprognostic (5.05e-2)" "unprognostic (9.26e-3)" 27.3 31.5 15.6 23.6 13.9 29.3 33.7 9.0 20.1 23.8 29.5 16.0 17.9 21.9 16.6 18.7 38.0 25.9 27.8 18.5 13.9 11.6 25.9 42.7 27.5 60.0 14.3 11.8 32.0 42.1 19.1 16.4 26.5 10.9 23.5 13.5 16.8 31.5 20.7 10.9 27.2 30.8 13.3 16.8 31.4 20.8 15.8 12.2 46.6 26.7 19.2 27.6 18.5 21.6 17.6 46.4 45.8 44.5 17.4 14.9 22.4 18.6 16.8 10.6 7.2 16.2 27.0 20.3 12.8 20.9 12.9 16.6 8.0 28.3 20.7 14.4 20.0 12.9 5.9 20.0 3.9 10.3 23.2 9.7 7.8 14.3 27.9 10.3 10.8 31.7 27.7 7.7 23.2 17.3 11.0 5.1 15.8 20.5 22.6 29.0 14.1 70.6 15.3 6.8 13.1 17.4 15.1 13.5 16.2 8.2 9.1 18.0 13.2 18.7 16.2 13.4 3.7 26.7 7.2 9.0 6.3 8.8 19.1 26.5 13.1 15.2 40.8 45.8 14.9 44.5 12.1 16.4 13.2 13.2 46.4 17.6 12.5 12.6 39.6 17.4 41.5 34.4 14.0 22.4 15.6 13.9 9.0 20.1 13.9 11.6 14.3 11.8 10.9 12.2 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 95.8" "Group enriched" "Detected in some" 6 "MCF7: 10.6;T-47d: 10.7" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.6;monocytes: 7.1;T-cells: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" 160000000000 "Cell Junctions" "CAB033468: AB_1127187, HPA046311: , HPA075237: " "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 3.6 7.1 0.6 3.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.7 0.0 0.0 0.2 0.0 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 3.6 0.7 0.3 2.6 2.4 2.5 0.3 1.6 1.3 0.2 0.0 3.6 3.7 2.5 0.6 7.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593276-63660245 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 233.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Approved Cytosol 20000000 Cytosol "CAB004666: AB_425590, HPA024190: AB_1855266, HPA024637: AB_1855267, HPA046329: " "unprognostic (2.50e-1)" "unprognostic (2.26e-3)" "unprognostic (1.74e-2)" "unprognostic (5.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-2)" "unprognostic (1.86e-3)" "unprognostic (2.42e-3)" "unprognostic (2.20e-1)" "prognostic unfavourable (8.74e-5)" "unprognostic (7.07e-2)" "unprognostic (1.55e-2)" "unprognostic (6.58e-3)" "unprognostic (1.37e-1)" "unprognostic (2.46e-1)" "unprognostic (9.74e-3)" 17.8 14.1 7.0 4.4 8.3 3.5 9.8 4.4 8.3 6.7 12.9 5.2 4.6 10.6 4.6 7.7 8.8 3.3 8.9 36.9 6.4 5.4 10.0 56.4 7.6 2.7 6.2 6.3 9.7 21.6 12.9 6.2 11.5 8.5 8.7 9.1 5.4 7.9 9.4 233.5 5.3 12.4 8.4 5.6 3.0 5.7 3.0 5.5 3.0 6.0 42.8 6.3 9.4 4.7 12.2 25.9 25.6 17.9 21.1 23.3 16.6 30.2 12.7 4.8 15.7 31.7 23.4 38.9 12.5 17.0 13.6 22.3 10.5 14.1 9.6 26.2 19.2 7.2 6.6 26.3 16.1 11.7 8.8 20.2 21.5 10.8 26.2 17.7 1.2 29.5 17.0 15.9 25.2 8.1 0.0 12.8 21.8 1.8 5.1 9.7 21.8 20.4 7.2 22.3 3.1 19.8 9.5 2.9 18.7 27.3 28.6 41.6 8.9 6.7 0.8 20.2 10.3 17.9 10.6 8.1 11.9 15.6 33.0 15.6 8.6 20.5 17.9 25.6 23.3 12.0 18.6 12.2 13.7 17.5 25.9 6.9 12.5 14.5 21.2 21.1 10.2 7.5 10.6 16.6 7.0 8.3 4.4 8.3 6.4 5.4 6.2 6.3 8.5 5.5 PGM2 FLJ10983 ENSG00000169299 "Phosphoglucomutase 2" Q96G03 4 37826633-37862937 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040676 Uncertain Approved "Intermediate filaments" 1900000 "Intermediate filaments" "HPA040676: AB_2677076" "unprognostic (3.11e-2)" "unprognostic (1.01e-2)" "prognostic favourable (2.14e-5)" "unprognostic (2.29e-1)" "unprognostic (3.94e-1)" "unprognostic (5.44e-2)" "unprognostic (1.70e-2)" "unprognostic (2.09e-3)" "unprognostic (5.32e-2)" "unprognostic (7.02e-2)" "unprognostic (5.37e-2)" "unprognostic (2.22e-2)" "unprognostic (6.72e-3)" "unprognostic (3.21e-2)" "unprognostic (1.88e-1)" "unprognostic (9.97e-2)" "unprognostic (1.02e-1)" 11.2 10.8 7.7 11.6 5.9 7.5 13.5 9.8 5.7 14.7 10.3 4.2 6.5 6.1 15.0 7.6 41.3 7.0 11.0 8.3 7.1 4.0 11.1 13.3 7.5 13.2 4.4 5.7 10.0 9.0 9.5 6.4 27.9 10.4 11.1 8.4 6.8 11.0 5.0 2.4 17.7 8.6 12.2 6.9 13.4 9.0 9.0 3.9 17.3 8.8 31.7 22.9 13.6 18.9 4.5 15.3 30.8 13.1 13.2 7.0 7.2 11.5 4.0 6.2 6.6 4.7 5.2 8.1 13.9 8.2 11.4 11.8 7.1 8.4 15.2 6.9 7.6 6.0 15.0 13.0 29.2 9.7 8.7 16.7 6.7 5.0 10.1 17.5 11.7 7.5 15.8 9.4 8.4 18.3 21.7 2.7 10.0 6.1 19.9 20.7 7.1 6.3 15.2 9.8 6.3 7.1 22.3 13.0 4.4 7.0 10.3 4.9 8.9 18.8 15.9 8.6 10.6 11.6 28.2 6.2 16.1 17.3 4.5 23.0 14.4 8.0 13.1 30.8 4.9 10.5 5.8 4.5 4.1 5.6 15.3 2.8 4.0 5.0 16.3 13.2 8.0 3.4 7.0 7.2 7.7 5.9 9.8 5.7 7.1 4.0 4.4 5.7 10.4 3.9 PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330318-74398473 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 48.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 13.1;LHCN-M2: 15.7;RH-30: 15.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056995, HPA060948" Enhanced Approved Mitochondria 64000 Mitochondria "HPA056995: , HPA060948: " "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" "unprognostic (7.28e-3)" "unprognostic (8.91e-2)" "unprognostic (6.16e-2)" "unprognostic (1.55e-1)" "unprognostic (7.16e-6)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (5.97e-3)" "unprognostic (1.70e-2)" "unprognostic (2.98e-1)" "unprognostic (9.33e-3)" "unprognostic (3.71e-1)" "unprognostic (1.97e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-2)" 3.0 4.0 30.6 4.9 19.8 4.0 3.2 6.3 48.6 6.1 4.5 1.3 1.0 2.3 6.1 1.9 2.1 4.7 4.8 1.6 30.1 15.1 2.5 2.1 2.7 4.0 9.7 20.4 1.7 4.4 1.4 4.5 2.1 11.7 3.8 5.1 2.9 3.2 2.5 7.1 1.7 2.6 5.6 2.6 2.5 3.4 2.3 0.3 10.0 4.1 1.3 4.0 5.2 2.6 2.4 1.7 2.5 0.6 3.0 7.5 1.1 2.0 2.9 11.5 2.1 3.5 1.5 0.3 2.7 2.1 2.4 2.6 1.0 5.4 0.2 6.8 1.8 1.0 2.3 0.5 2.3 0.8 1.2 1.6 1.6 0.9 0.4 1.9 2.6 0.8 0.5 5.4 1.0 13.1 2.1 1.4 15.7 0.3 7.4 1.6 2.3 2.6 2.3 15.0 0.1 6.2 0.4 0.5 2.3 4.4 1.0 2.0 0.2 0.3 10.9 5.3 5.0 2.1 2.8 1.9 2.8 0.2 0.5 2.6 1.2 2.5 0.6 1.1 2.1 0.6 2.8 2.4 3.5 2.3 0.5 1.8 3.3 1.9 0.7 3.0 0.3 1.7 7.5 1.1 30.6 19.8 6.3 24.4 30.1 15.1 9.7 20.4 11.7 0.3 PGM3 "AGM1, DKFZP434B187, PAGM" ENSG00000013375 "Phosphoglucomutase 3" O95394 6 83161150-83193936 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004998, HPA029759, HPA029760" Enhanced Approved Nucleoplasm,Cytosol 73000 "Nucleoplasm, Cytosol" "CAB004998: AB_425591, HPA029759: AB_10600305, HPA029760: AB_10601109" "prognostic unfavourable (8.78e-4)" "prognostic unfavourable (5.67e-4)" "unprognostic (1.45e-2)" "unprognostic (3.03e-2)" "unprognostic (1.51e-2)" "unprognostic (4.04e-2)" "unprognostic (1.09e-3)" "unprognostic (6.72e-3)" "unprognostic (3.11e-1)" "prognostic favourable (9.96e-4)" "unprognostic (4.00e-1)" "unprognostic (1.30e-1)" "prognostic unfavourable (2.39e-7)" "unprognostic (2.21e-1)" "unprognostic (7.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.22e-3)" 15.5 16.7 11.2 10.4 13.7 4.8 12.3 19.1 13.3 15.4 10.1 9.0 30.7 8.9 10.6 26.2 10.3 8.8 14.2 12.2 11.0 8.6 12.2 44.9 13.4 6.3 13.5 9.9 15.5 36.3 9.3 36.2 27.6 18.1 30.9 13.7 7.4 29.2 23.4 5.5 7.5 11.6 11.1 9.7 8.1 14.4 16.8 11.3 4.0 14.9 7.6 8.7 11.1 10.0 8.2 7.4 11.1 6.5 5.3 8.7 3.9 10.0 6.6 12.9 15.4 21.0 22.4 14.9 34.3 24.9 16.6 26.2 17.2 4.7 5.3 7.3 34.2 6.4 11.7 14.4 31.9 3.9 11.4 6.8 13.1 28.8 23.8 6.6 3.4 14.2 11.9 29.3 37.1 19.5 22.1 5.8 17.9 10.4 1.1 4.4 5.7 9.1 4.7 28.8 3.1 12.9 9.9 5.1 8.0 9.9 8.8 6.8 7.7 7.4 28.5 11.5 6.3 23.0 18.4 11.3 4.4 3.8 9.0 5.3 17.9 11.1 6.4 3.8 5.0 6.0 6.7 8.2 5.2 6.2 5.5 5.0 8.7 8.2 2.7 5.3 6.5 7.4 3.6 3.9 11.2 13.7 19.1 13.3 11.0 8.6 13.5 9.9 18.1 11.3 PGP ENSG00000184207 "Phosphoglycolate phosphatase" A6NDG6 16 2211997-2214807 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 40.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043096, HPA046739" Approved Approved "Nuclear bodies" 46000 "Nuclear bodies" "HPA043096: AB_2678311, HPA046739: AB_2679779" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (2.36e-2)" "unprognostic (7.23e-2)" "unprognostic (2.12e-3)" "unprognostic (1.76e-1)" "unprognostic (5.75e-3)" "unprognostic (5.87e-2)" "unprognostic (7.90e-2)" "unprognostic (4.43e-3)" "unprognostic (6.50e-2)" "unprognostic (9.04e-2)" "prognostic favourable (7.05e-4)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "prognostic favourable (6.42e-4)" 5.7 7.2 10.9 7.3 12.5 9.2 3.6 31.4 21.4 3.9 6.7 4.8 7.3 7.9 4.7 6.5 3.6 3.7 4.4 15.6 11.4 9.8 6.1 5.5 6.2 7.5 9.6 12.8 2.5 6.6 8.7 6.1 6.9 17.8 5.3 5.3 4.7 6.2 6.8 40.7 5.6 7.5 4.9 6.0 8.0 6.7 23.0 7.4 5.9 8.8 7.9 5.0 4.2 2.6 1.8 1.9 6.1 3.4 0.3 2.2 0.4 9.1 15.0 10.7 10.1 4.4 3.5 20.5 10.8 5.2 10.0 10.3 23.3 11.6 7.0 10.6 5.0 15.5 7.5 9.2 4.4 9.4 20.8 7.0 22.9 10.5 3.0 12.4 11.6 4.2 4.1 9.3 3.5 6.4 12.7 7.4 5.5 25.0 13.9 20.2 14.1 14.2 22.8 9.3 15.7 8.2 5.8 14.3 8.7 9.6 18.1 7.4 13.4 14.5 6.3 10.3 13.5 9.2 10.7 17.6 7.6 9.9 3.4 11.0 8.0 0.0 2.3 6.1 2.2 3.4 0.3 0.7 1.3 1.6 1.6 1.8 0.8 1.4 1.4 0.3 3.1 1.9 1.3 0.4 10.9 12.5 31.4 21.4 11.4 9.8 9.6 12.8 17.8 7.4 PGPEP1 "Pcp, PGP, PGP-I, PGPI" ENSG00000130517 "Pyroglutamyl-peptidase I" Q9NXJ5 19 18340587-18369950 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035368, HPA055277" Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA035368: AB_10601388, HPA055277: " "unprognostic (9.52e-3)" "unprognostic (1.37e-2)" "unprognostic (6.95e-2)" "unprognostic (5.74e-3)" "unprognostic (5.29e-2)" "unprognostic (6.60e-2)" "unprognostic (1.96e-2)" "unprognostic (2.11e-3)" "prognostic favourable (6.80e-4)" "unprognostic (2.79e-2)" "prognostic favourable (1.71e-4)" "unprognostic (4.81e-3)" "prognostic favourable (3.71e-8)" "unprognostic (1.12e-2)" "unprognostic (1.66e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-3)" 11.0 18.6 14.8 10.1 14.9 12.4 10.7 8.1 12.5 13.9 23.3 14.8 25.3 23.6 8.2 16.0 6.3 10.0 16.7 20.6 18.2 15.4 29.9 29.7 9.4 11.4 17.8 7.3 13.2 26.6 15.1 17.1 7.5 12.5 13.4 17.2 13.7 22.8 23.6 25.2 3.6 33.6 12.1 25.5 16.2 15.4 4.2 15.6 8.6 11.5 7.4 7.0 12.8 10.0 3.9 3.3 17.6 6.1 4.3 4.9 3.6 4.7 7.5 6.2 6.3 7.9 6.2 7.6 5.6 8.8 3.9 5.8 5.3 10.1 7.2 9.5 9.2 1.2 2.4 1.3 2.2 8.5 2.7 7.9 7.5 14.8 11.2 4.6 33.2 6.3 2.8 3.0 0.5 5.8 14.5 11.0 3.2 7.6 4.7 3.7 6.3 2.3 0.0 2.3 6.4 4.2 7.4 2.2 3.5 1.1 0.6 10.0 2.8 9.5 8.9 4.5 3.0 5.8 2.4 13.7 6.5 4.3 12.0 13.2 4.1 17.6 5.4 7.1 4.9 5.4 2.8 2.0 3.4 4.4 3.3 3.9 4.3 4.0 3.1 4.3 6.1 2.2 3.8 3.6 14.8 14.9 8.1 12.5 18.2 15.4 17.8 7.3 12.5 15.6 PGPEP1L ENSG00000183571 "Pyroglutamyl-peptidase I-like" A6NFU8 15 98968230-99007795 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 34.7" "Cell line enhanced" "Detected in some" "HeLa: 1.9;U-2 OS: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 6 "basophil: 2.0;neutrophil: 1.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.0" "Not detected" "Not detected" HPA041781 Uncertain "HPA041781: AB_10795642" "unprognostic (2.48e-1)" "unprognostic (2.82e-2)" "unprognostic (8.26e-2)" "unprognostic (2.43e-3)" "unprognostic (7.18e-2)" "unprognostic (3.99e-2)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (9.78e-2)" "unprognostic (1.58e-1)" "unprognostic (4.53e-3)" "unprognostic (1.86e-1)" "unprognostic (2.62e-1)" "unprognostic (2.00e-2)" "unprognostic (1.65e-1)" 0.7 0.1 0.5 0.2 1.4 0.1 0.6 0.2 0.5 0.4 0.4 0.4 0.0 0.2 0.2 0.4 0.8 0.2 0.5 3.6 0.6 0.4 0.4 0.0 0.2 0.3 0.4 0.2 0.2 0.5 0.0 0.1 0.3 0.4 0.6 0.0 1.6 0.9 0.5 34.7 0.1 0.2 0.3 0.3 0.1 0.2 5.0 0.2 0.1 0.1 8.6 0.5 0.2 0.3 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.1 0.7 0.0 0.2 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 1.9 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.9 1.4 0.1 0.0 0.2 0.4 1.3 0.4 0.4 0.1 1.2 0.0 0.9 0.3 0.4 0.5 1.4 0.2 0.8 0.0 0.7 0.0 4.4 0.2 0.1 0.8 0.2 0.7 0.0 0.5 0.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 1.4 0.2 0.5 0.6 0.4 0.4 0.2 0.4 0.2 PGS1 DKFZP762M186 ENSG00000087157 "Phosphatidylglycerophosphate synthase 1" Q32NB8 17 78378640-78425114 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022526 Approved Approved "Vesicles,Cell Junctions,Intermediate filaments" "Vesicles, Cell Junctions, Intermediate filaments" "HPA022526: AB_1855271" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (1.86e-3)" "unprognostic (1.35e-2)" "unprognostic (1.71e-2)" "prognostic unfavourable (1.37e-4)" "unprognostic (5.76e-3)" "unprognostic (3.17e-2)" "unprognostic (8.46e-3)" "prognostic favourable (7.33e-5)" "prognostic unfavourable (9.94e-4)" "prognostic unfavourable (1.16e-5)" "unprognostic (9.94e-2)" "unprognostic (5.60e-2)" "unprognostic (1.33e-1)" "unprognostic (2.72e-2)" 16.4 11.6 14.5 20.8 20.3 41.4 28.2 17.6 17.4 14.4 13.1 18.4 13.2 13.7 17.3 13.2 14.5 16.9 17.2 14.0 15.7 16.1 14.3 8.0 25.5 19.1 21.6 17.0 18.3 14.0 16.0 13.3 24.0 15.3 13.9 10.2 12.9 13.1 16.8 13.8 11.9 15.1 13.4 18.0 22.6 12.6 13.9 18.8 17.7 18.6 7.8 14.3 16.9 32.3 8.0 14.0 26.0 12.6 6.7 11.3 8.4 13.1 11.6 11.3 8.5 10.0 16.0 13.4 12.4 11.9 13.3 14.7 10.8 10.4 13.6 7.5 7.0 10.2 13.4 8.4 10.5 20.4 15.2 14.9 13.8 10.8 9.8 11.2 12.1 16.3 11.1 9.6 8.7 25.4 17.3 9.5 9.0 7.2 25.3 10.1 11.8 11.2 13.3 20.3 11.6 13.0 12.1 15.0 22.8 10.6 11.7 11.3 12.3 13.6 15.9 17.3 12.0 9.2 10.4 10.5 6.2 10.3 13.1 12.6 12.8 1.5 12.6 13.2 8.4 10.4 9.8 7.8 8.8 8.8 14.0 8.0 11.3 8.1 26.0 6.7 4.6 6.6 10.4 8.4 14.5 20.3 17.6 17.4 15.7 16.1 21.6 17.0 15.3 18.8 PHF8 "JHDM1F, KDM7B, KIAA1111, ZNF422" ENSG00000172943 "PHD finger protein 8" Q9UPP1 X 53936676-54048958 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, Oxidoreductase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038779, HPA062015" Approved Supported Nucleoplasm Nucleoplasm "HPA038779: AB_10675950, HPA062015: " "unprognostic (6.35e-2)" "unprognostic (2.16e-2)" "unprognostic (1.70e-2)" "unprognostic (1.04e-1)" "unprognostic (8.76e-2)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "unprognostic (2.66e-3)" "unprognostic (1.97e-3)" "unprognostic (1.22e-1)" "unprognostic (5.64e-2)" "unprognostic (1.02e-1)" "unprognostic (5.17e-2)" "unprognostic (1.22e-1)" "unprognostic (9.94e-2)" "unprognostic (1.85e-2)" "prognostic favourable (3.74e-5)" 8.8 6.8 8.2 11.5 9.4 10.7 11.1 12.5 9.2 10.3 8.2 12.9 27.4 7.9 12.2 54.0 10.7 11.1 9.8 7.8 7.2 5.4 8.8 21.7 10.5 11.2 11.3 7.0 16.8 14.1 10.6 14.6 9.8 9.4 12.8 7.5 10.3 10.3 14.7 8.4 9.6 11.1 8.9 8.5 11.8 9.7 30.6 10.4 19.6 11.1 8.1 13.0 12.8 16.1 6.2 5.1 10.7 7.9 5.4 9.5 5.1 8.8 7.7 11.7 11.3 7.3 5.7 19.2 6.7 5.9 7.5 6.7 8.7 7.2 13.0 4.0 6.0 9.3 29.0 5.8 8.0 20.2 13.8 7.8 9.9 8.7 5.7 12.1 14.7 6.4 8.1 8.6 11.8 6.9 10.3 19.0 4.3 8.8 16.5 9.3 21.2 11.6 16.3 13.0 12.7 5.1 10.7 17.1 8.4 17.8 11.9 5.9 11.8 8.5 7.9 6.0 8.5 11.0 5.5 14.5 13.3 15.7 7.0 15.4 6.4 10.7 4.5 7.2 6.2 7.9 9.5 4.3 6.2 7.1 5.1 6.2 4.6 5.0 7.7 5.4 5.2 4.0 9.2 5.1 8.2 9.4 12.5 9.2 7.2 5.4 11.3 7.0 9.4 10.4 PHGDH "PDG, PGDH, SERA" ENSG00000092621 "Phosphoglycerate dehydrogenase" O43175 1 119648411-119744226 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD8 T-cell: 16.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003681, HPA021241, HPA024031, CAB068216" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" 9000000 "Plasma membrane, Cytosol" Nucleoplasm "CAB003681: AB_425928, CAB068216: , HPA021241: AB_1855299, HPA024031: AB_1855300" "unprognostic (2.30e-1)" "unprognostic (2.16e-1)" "unprognostic (1.80e-2)" "prognostic unfavourable (1.48e-4)" "prognostic favourable (1.62e-4)" "unprognostic (9.80e-2)" "unprognostic (1.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.24e-2)" "unprognostic (4.45e-3)" "unprognostic (8.80e-3)" "unprognostic (5.00e-2)" "unprognostic (2.37e-2)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (1.78e-3)" 18.8 1.9 33.3 4.4 32.1 4.4 13.8 7.8 27.2 11.9 5.8 49.7 9.4 4.2 6.1 41.0 16.7 24.5 3.9 5.3 26.7 20.5 14.0 53.2 4.3 5.7 42.0 20.7 17.3 58.2 67.5 5.7 6.4 23.3 24.5 4.7 8.7 62.9 16.4 1.7 35.9 3.0 8.1 28.3 1.9 9.0 8.6 38.1 9.9 15.8 7.3 7.3 7.9 14.1 6.7 3.2 2.9 0.7 1.2 16.5 3.2 13.5 5.5 14.5 34.9 8.3 11.0 27.1 12.3 22.2 17.6 29.2 28.7 2.4 0.0 5.3 32.9 18.3 26.9 25.6 12.4 0.1 24.5 4.3 19.5 19.8 17.3 27.4 0.1 15.8 42.8 16.8 20.0 12.6 7.8 32.5 7.7 53.3 18.3 8.4 36.3 42.3 16.1 25.2 2.3 1.1 16.2 15.7 14.3 9.0 6.0 98.9 12.2 46.8 0.1 2.9 15.3 17.9 13.7 26.8 6.7 27.4 35.6 38.3 22.6 2.9 0.7 0.2 2.9 0.2 0.2 6.7 1.8 4.9 3.2 2.7 9.1 16.5 2.0 1.2 0.2 1.8 2.4 3.2 33.3 32.1 7.8 27.2 26.7 20.5 42.0 20.7 23.3 38.1 PHKG1 PHKG ENSG00000164776 "Phosphorylase kinase catalytic subunit gamma 1" Q16816 7 56080283-56092996 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 105.6;tongue: 32.9" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in many" 18 "glioma: 23.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012057 Enhanced "HPA012057: AB_1855305" "unprognostic (2.00e-3)" "unprognostic (1.09e-1)" "unprognostic (7.09e-3)" "unprognostic (5.87e-3)" "unprognostic (2.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (6.69e-3)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (9.14e-4)" "unprognostic (1.92e-1)" "unprognostic (7.97e-9)" "unprognostic (6.61e-3)" "unprognostic (2.34e-1)" "unprognostic (1.12e-2)" "unprognostic (3.85e-2)" 2.0 1.5 4.9 0.8 6.1 1.1 1.5 6.0 5.8 0.7 2.6 6.5 0.0 1.0 0.9 1.5 3.2 0.9 1.1 11.8 4.1 2.9 0.6 0.7 0.9 0.8 3.5 3.9 1.0 0.8 1.2 0.6 0.6 6.8 1.4 0.8 0.0 1.6 0.8 105.6 1.6 0.9 1.1 3.6 0.8 0.8 0.7 4.8 0.0 0.6 32.9 1.2 1.8 0.3 1.3 0.6 3.3 0.7 0.3 1.9 0.2 2.9 2.1 0.5 1.7 3.1 5.3 1.4 0.3 0.6 1.0 0.8 0.7 1.3 0.8 0.5 1.0 1.5 1.2 0.2 0.8 0.8 2.1 0.8 2.9 0.7 0.8 1.5 3.2 3.3 2.2 1.6 0.7 0.3 2.2 3.9 0.1 1.3 2.2 5.5 1.0 1.3 1.2 0.3 1.0 0.6 1.9 1.5 1.6 0.3 2.1 0.1 1.1 1.9 0.8 0.5 1.7 4.4 1.1 1.8 0.7 2.2 1.2 1.4 1.0 0.4 0.5 0.0 0.8 0.2 1.9 0.3 1.2 0.3 0.2 1.3 0.6 0.6 3.3 0.3 0.7 0.6 0.5 0.2 4.9 6.1 6.0 5.8 4.1 2.9 3.5 3.9 6.8 4.8 PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748270-30761176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 44.5;testis: 95.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol Cytosol "HPA065618: AB_2685520, HPA068751: AB_2686025" "unprognostic (7.63e-3)" "prognostic favourable (7.90e-4)" "prognostic unfavourable (9.92e-4)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "prognostic favourable (1.90e-4)" "unprognostic (6.45e-2)" "unprognostic (1.25e-2)" "prognostic favourable (8.02e-4)" "unprognostic (6.15e-2)" "unprognostic (5.27e-2)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" 4.3 8.3 8.7 6.9 8.0 15.9 5.8 9.1 12.0 4.7 7.9 7.3 9.0 6.8 5.6 7.8 5.3 6.8 7.2 6.4 9.0 9.3 8.2 11.0 5.8 6.8 8.6 9.2 4.7 5.1 17.3 8.5 6.3 11.8 7.7 7.6 6.4 7.0 9.9 6.4 8.4 7.3 6.3 5.8 6.9 7.2 95.4 7.3 5.5 8.6 5.5 7.7 5.2 4.7 8.8 21.2 44.5 22.7 23.5 16.8 17.6 13.5 8.9 7.5 9.2 7.1 5.7 16.9 9.5 14.3 13.0 14.9 7.7 6.8 11.7 11.3 9.8 13.0 7.8 12.1 10.5 6.3 21.7 6.4 14.8 21.6 10.9 9.9 9.2 7.7 6.6 12.5 5.9 13.2 8.7 6.8 9.4 31.2 11.7 14.6 10.3 10.4 15.8 11.7 15.6 14.9 15.3 10.1 7.0 7.7 21.5 9.1 16.9 8.6 7.8 8.0 8.9 10.0 8.7 13.8 7.5 8.0 15.9 19.4 6.5 14.0 22.7 44.5 16.2 22.4 13.3 8.8 11.6 16.4 21.2 8.5 10.4 12.1 18.2 23.5 15.9 18.2 16.8 17.6 8.7 8.0 9.1 12.0 9.0 9.3 8.6 9.2 11.8 7.3 PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715450-62980433 "Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 7.7;T-reg: 2.4" "Group enriched" "Detected in many" 7 "granulocytes: 7.7;T-cells: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Uncertain "Intracellular and membrane" "HPA020200: " "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.07e-2)" "unprognostic (5.57e-2)" "unprognostic (5.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.10e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "prognostic favourable (5.35e-8)" "unprognostic (1.52e-1)" "unprognostic (3.49e-2)" "unprognostic (8.13e-2)" "unprognostic (8.25e-2)" 5.8 10.6 22.1 2.3 34.1 7.4 7.4 8.3 29.6 4.3 6.0 48.0 0.9 6.2 4.4 2.5 6.1 4.0 4.9 3.0 22.4 12.3 4.0 18.5 3.4 3.0 44.4 13.8 5.5 8.0 9.6 5.6 6.3 20.6 5.0 6.7 4.4 11.2 4.5 3.9 9.1 5.5 4.0 18.6 2.0 5.6 11.5 44.8 2.3 5.6 1.6 4.1 5.6 3.2 0.6 0.7 7.7 0.2 0.6 2.4 0.1 8.9 3.4 13.8 4.6 2.3 2.0 10.8 2.7 2.4 5.4 5.5 7.3 5.4 6.0 1.6 4.0 11.0 7.1 4.2 6.9 18.6 5.9 2.0 3.7 13.4 3.3 3.0 1.0 2.1 2.8 5.7 5.3 3.8 5.1 12.2 5.1 2.0 2.2 2.6 5.6 3.3 21.4 7.8 7.2 3.0 11.6 6.4 2.6 2.9 6.7 5.5 2.9 8.8 4.8 4.4 2.1 2.6 6.2 1.4 0.7 7.1 2.6 3.5 3.3 0.0 0.2 0.1 0.7 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.4 0.1 7.7 0.6 0.2 0.3 2.4 0.1 22.1 34.1 8.3 21.1 22.4 12.3 44.4 13.8 20.6 44.8 PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 29.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048598 Approved Approved Vesicles Vesicles "HPA048598: " "unprognostic (5.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-1)" "unprognostic (1.97e-4)" "unprognostic (3.08e-2)" "unprognostic (8.85e-3)" "unprognostic (6.41e-2)" "unprognostic (4.92e-2)" "unprognostic (8.46e-3)" "unprognostic (8.27e-2)" 6.4 4.7 12.5 7.0 10.9 8.1 8.4 17.4 14.9 4.4 16.6 4.6 4.3 15.8 5.8 4.9 2.7 4.7 4.1 4.6 11.7 9.0 5.4 4.9 4.8 5.0 6.2 14.9 7.2 4.9 10.2 7.3 4.3 12.6 4.7 17.8 13.2 2.9 5.7 5.3 3.0 29.9 7.0 7.6 3.9 4.2 10.8 4.7 1.0 9.9 1.1 4.9 4.7 9.8 2.4 2.2 1.2 0.7 3.5 1.5 0.4 4.8 6.4 7.0 7.8 5.6 6.8 4.0 7.3 6.6 10.6 8.6 5.9 1.6 9.6 2.9 12.0 10.3 10.1 3.7 13.7 3.4 5.5 2.7 5.5 3.8 4.4 2.3 4.2 5.0 2.2 15.0 4.9 3.9 2.4 2.6 7.3 10.2 3.1 1.8 5.5 1.7 5.1 6.2 3.1 5.0 3.7 6.1 3.2 15.7 4.3 2.5 5.3 1.3 5.4 10.7 7.7 4.5 6.0 6.1 4.2 10.0 6.6 1.9 2.3 0.8 0.5 0.2 1.0 0.7 0.9 2.4 0.8 1.5 0.6 1.6 1.1 0.9 1.2 3.5 0.7 2.2 1.3 0.4 12.5 10.9 17.4 14.9 11.7 9.0 6.2 14.9 12.6 4.7 PHOSPHO1 ENSG00000173868 "Phosphoethanolamine/phosphocholine phosphatase" Q8TCT1 17 49223362-49230766 "Enzymes, Predicted intracellular proteins" "Mineral balance" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 80.0;testis: 52.3" "Cell line enhanced" "Detected in some" "Daudi: 9.2;EFO-21: 6.2;HDLM-2: 6.5" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 4 "cerebral cortex: 10.2;pons and medulla: 8.2" "Group enriched" "Detected in some" 171 "eosinophil: 30.6;neutrophil: 80.0" "Lineage enriched" "Detected in single" 248 "granulocytes: 80.0" "Low region specificity" "Detected in all" HPA065025 Approved "Plasma membrane,Actin filaments" "Actin filaments" "Plasma membrane" "HPA065025: " "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (7.53e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-1)" "unprognostic (4.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-2)" "unprognostic (2.04e-1)" "unprognostic (6.88e-2)" "unprognostic (1.02e-2)" "unprognostic (2.88e-1)" "unprognostic (2.03e-1)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (1.87e-1)" 2.5 1.3 1.1 2.9 1.9 15.3 0.7 1.0 10.2 0.6 0.6 0.2 0.2 2.5 0.9 2.7 0.9 1.3 2.1 1.0 1.7 1.3 1.0 0.9 2.5 2.0 2.1 1.5 1.1 1.0 0.1 0.8 7.6 8.2 0.9 0.0 1.6 0.9 0.5 2.2 1.1 2.6 0.3 1.5 12.6 0.7 52.3 0.1 0.0 0.8 0.1 0.1 1.4 1.3 0.0 0.0 80.0 0.3 0.0 0.0 0.1 0.0 1.2 0.0 2.1 0.1 0.2 0.0 0.3 0.4 0.0 0.2 2.9 0.0 9.2 6.2 0.0 0.0 1.7 0.5 0.1 6.5 0.2 1.2 1.2 0.4 0.0 0.0 1.1 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 1.7 1.8 3.5 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.2 3.7 0.5 3.0 2.0 0.0 0.3 0.3 0.6 2.7 3.5 0.3 0.0 0.1 30.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.0 0.0 0.3 0.0 0.0 0.1 1.1 1.9 1.0 10.2 1.7 1.3 2.1 1.5 8.2 0.1 PHOSPHO2 MGC22679 ENSG00000144362 "Phosphatase, orphan 2" Q8TCD6 2 169694454-169701708 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034726, HPA034727" Uncertain Approved Vesicles Vesicles "HPA034726: AB_10602191, HPA034727: " "unprognostic (1.98e-1)" "unprognostic (1.22e-1)" "unprognostic (7.56e-2)" "unprognostic (1.39e-3)" "unprognostic (1.30e-2)" "unprognostic (2.26e-1)" "prognostic unfavourable (3.82e-6)" "unprognostic (4.31e-2)" "unprognostic (2.11e-2)" "unprognostic (5.19e-2)" "unprognostic (1.40e-1)" "unprognostic (2.31e-1)" "prognostic favourable (9.53e-4)" "unprognostic (4.10e-1)" "unprognostic (2.60e-1)" "unprognostic (6.12e-2)" "unprognostic (7.53e-2)" 8.7 4.0 9.0 5.7 9.7 3.3 14.2 14.2 7.8 8.4 8.2 5.8 6.3 8.2 8.6 5.9 4.6 8.1 6.2 5.7 6.7 5.5 7.5 5.0 4.3 3.6 6.0 9.1 8.2 8.9 10.9 21.3 3.9 7.8 17.4 7.8 6.4 10.5 7.8 6.4 5.2 7.9 6.2 9.7 3.4 6.3 25.4 8.0 5.5 13.0 3.9 3.9 9.1 5.7 8.8 4.6 1.5 1.0 10.5 5.7 1.8 5.6 1.6 4.1 5.5 7.8 2.5 16.0 2.5 1.7 3.8 4.3 5.5 4.4 5.5 5.6 1.8 4.4 5.4 3.0 3.2 8.1 6.3 5.5 4.8 9.5 5.1 4.5 5.0 4.5 5.7 4.4 5.9 3.4 9.1 5.7 2.4 5.2 3.1 5.8 5.5 2.1 3.2 2.5 4.3 6.1 17.0 17.2 5.9 5.3 2.8 5.9 7.4 2.7 2.0 4.2 4.0 4.0 2.7 5.5 5.1 4.9 5.0 2.7 4.5 0.0 0.9 1.1 3.9 1.0 5.5 6.8 4.3 3.7 1.0 8.8 5.7 5.6 1.5 10.5 0.9 4.6 4.4 1.8 9.0 9.7 14.2 7.8 6.7 5.5 6.0 9.1 7.8 8.0 PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013584, HPA020952" Approved Approved "Nuclear bodies,Cytosol" 430000 Cytosol "Nuclear bodies" "CAB013584: , HPA020952: AB_1855331" "unprognostic (7.34e-2)" "unprognostic (9.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.30e-1)" "unprognostic (4.64e-2)" "unprognostic (1.69e-2)" "unprognostic (3.23e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-3)" "unprognostic (5.85e-2)" "unprognostic (9.66e-3)" "unprognostic (1.11e-2)" "unprognostic (2.01e-1)" "unprognostic (3.95e-2)" "unprognostic (8.49e-2)" 15.8 26.4 31.5 12.1 28.0 11.7 15.3 14.7 27.2 19.2 15.7 18.5 13.7 14.7 11.2 21.7 13.7 21.1 14.2 59.1 22.7 19.3 18.4 12.6 12.1 12.7 27.0 21.0 13.7 46.5 15.6 21.2 14.7 20.8 20.2 11.6 14.1 30.5 22.6 86.0 9.2 16.3 16.9 24.3 10.3 13.4 13.8 18.6 7.5 20.7 19.8 10.4 12.0 9.8 24.9 48.8 3.3 35.4 20.0 24.3 32.1 7.1 52.2 29.8 19.0 19.3 35.0 43.8 16.7 21.3 20.4 18.1 19.0 16.3 15.2 20.3 20.6 19.0 6.5 37.7 6.4 13.6 13.2 4.8 34.3 41.7 24.0 9.5 19.6 43.6 31.0 11.7 14.1 26.7 11.5 14.2 31.6 40.7 13.9 20.1 23.6 22.5 11.5 13.0 25.1 32.2 11.9 14.6 13.9 17.9 21.1 8.7 16.0 26.5 21.7 42.6 13.2 11.8 15.4 9.4 9.1 9.3 24.1 6.9 25.5 2.9 35.4 3.3 24.3 34.2 20.9 24.9 21.1 21.9 37.5 16.5 15.0 21.3 1.7 20.0 24.0 48.8 22.9 32.1 31.5 28.0 14.7 27.2 22.7 19.3 27.0 21.0 20.8 18.6 PHYH "PAHX, PHYH1, RD" ENSG00000107537 "Phytanoyl-CoA 2-hydroxylase" O14832 10 13277796-13302412 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cataract, Deafness, Disease mutation, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 128.3;skeletal muscle: 83.8" "Cell line enhanced" "Detected in many" "ASC diff: 42.1" "Cancer enhanced" "Detected in all" "liver cancer: 78.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007598, HPA011796" Enhanced "HPA007598: AB_1855334, HPA011796: AB_1855335" "unprognostic (5.78e-2)" "unprognostic (3.83e-1)" "unprognostic (6.98e-2)" "unprognostic (3.62e-2)" "unprognostic (5.52e-2)" "unprognostic (1.61e-3)" "unprognostic (1.16e-1)" "unprognostic (1.95e-2)" "unprognostic (7.09e-2)" "unprognostic (6.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.24e-1)" "prognostic favourable (7.28e-12)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.19e-1)" 10.5 16.8 5.3 5.3 6.2 1.4 7.7 5.1 8.7 6.0 10.7 5.4 5.7 11.4 5.4 5.6 6.8 3.6 8.5 38.0 4.0 4.9 36.4 128.3 6.4 3.2 6.5 3.7 7.6 9.9 6.8 6.7 4.5 5.3 6.2 7.4 7.1 6.3 5.4 83.8 3.8 15.5 10.2 4.4 3.0 8.5 4.1 4.1 1.9 13.0 29.5 3.6 7.6 9.4 9.2 13.3 10.7 16.0 3.3 15.4 10.2 6.1 12.8 5.8 8.3 42.1 26.9 4.6 6.3 8.8 7.2 7.2 3.3 11.2 0.3 4.9 10.5 2.9 7.5 7.4 4.5 14.8 4.0 5.3 3.6 13.0 20.9 0.9 10.0 19.1 10.7 7.8 3.1 6.9 3.0 11.9 16.7 5.7 3.2 4.2 5.3 4.7 5.7 9.0 2.0 15.0 7.9 2.0 6.3 23.6 0.5 11.5 24.0 15.9 2.3 11.1 4.1 13.6 4.2 13.7 9.2 1.2 14.4 6.8 4.3 10.7 16.0 6.5 7.2 11.7 15.4 9.2 9.1 9.2 13.3 4.9 11.5 11.7 0.6 3.3 9.0 12.2 8.6 10.2 5.3 6.2 5.1 8.7 4.0 4.9 6.5 3.7 5.3 4.1 PHYKPL "AGXT2L2, MGC15875" ENSG00000175309 "5-phosphohydroxy-L-lysine phospho-lyase" Q8IUZ5 5 178208497-178232791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036461, HPA063608" Approved Approved Mitochondria 190000 Mitochondria "HPA036461: AB_10670717, HPA063608: " "unprognostic (3.29e-3)" "unprognostic (2.60e-1)" "unprognostic (5.51e-2)" "unprognostic (9.75e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-2)" "unprognostic (3.29e-1)" "unprognostic (5.38e-2)" "unprognostic (1.02e-3)" "prognostic unfavourable (3.82e-5)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.41e-3)" 18.7 13.1 10.5 25.0 10.8 9.8 15.5 8.3 10.9 13.9 24.3 13.4 14.4 15.1 13.5 14.9 10.7 13.6 17.5 15.5 8.9 4.9 18.1 44.4 14.7 16.8 13.7 9.3 13.2 18.0 11.9 11.9 11.8 10.2 12.4 23.9 12.1 12.3 13.7 20.2 7.6 29.8 14.1 10.7 20.2 15.3 16.4 11.7 16.3 16.6 10.5 17.4 14.0 11.8 13.9 32.8 16.7 21.7 10.7 14.0 14.3 5.7 2.4 5.7 2.3 14.4 11.4 8.6 3.6 4.0 4.8 7.7 6.1 7.3 7.5 10.9 11.0 3.7 4.9 9.2 5.6 15.3 4.9 9.6 9.6 4.3 23.4 5.4 6.1 13.1 9.7 6.0 14.8 16.0 6.9 17.3 7.2 8.4 7.5 2.8 1.1 7.9 5.0 2.7 15.0 8.8 5.2 3.5 3.3 5.7 3.3 6.0 3.6 4.4 6.4 5.0 4.6 3.2 3.8 11.1 3.0 4.5 1.4 5.8 3.3 6.3 19.5 16.7 10.0 21.7 10.1 13.9 11.3 11.4 25.2 12.6 14.0 11.3 4.4 10.7 21.3 32.8 12.9 14.3 10.5 10.8 8.3 10.9 8.9 4.9 13.7 9.3 10.2 11.7 PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640686-97676434 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" "Plasma membrane" "CAB030649: , HPA076857: " "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavourable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" 17.2 23.0 13.8 10.7 21.2 22.8 9.5 16.8 33.8 12.0 9.1 16.8 9.5 10.9 12.8 15.5 18.3 8.9 16.1 15.2 14.5 17.9 14.7 17.1 15.0 11.0 15.9 15.7 10.6 9.5 23.2 15.5 19.9 30.7 10.3 10.2 23.8 10.1 12.7 11.3 15.3 9.9 15.0 9.9 14.4 8.8 14.9 7.5 8.2 12.0 8.8 11.8 13.6 11.2 4.1 3.7 1.1 3.4 1.9 4.0 1.6 12.0 9.1 7.5 13.4 16.2 11.7 6.1 12.1 26.7 19.1 20.3 8.2 12.0 4.4 7.2 15.3 11.7 8.4 24.1 15.9 5.3 7.1 3.9 6.4 7.4 15.5 3.5 5.6 12.3 20.6 20.0 35.6 9.7 6.1 7.2 13.2 6.1 7.6 2.7 4.8 8.6 3.6 7.8 4.3 13.1 11.3 2.5 8.4 10.2 2.6 15.0 7.1 5.6 10.7 9.1 6.8 10.8 9.3 6.4 7.5 7.2 16.9 2.1 2.9 0.0 3.4 0.0 4.0 2.3 2.8 4.1 1.7 3.4 3.7 1.9 1.4 2.6 1.1 1.9 1.6 1.7 3.1 1.6 13.8 21.2 16.8 33.8 14.5 17.9 15.9 15.7 30.7 7.5 PI4K2B "FLJ11105, PI4KIIB, PIK42B" ENSG00000038210 "Phosphatidylinositol 4-kinase type 2 beta" Q8TCG2 4 25233975-25279092 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 49.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA004099 Approved Supported Cytosol Cytosol "HPA004099: AB_1855353" "unprognostic (1.02e-1)" "unprognostic (6.34e-3)" "prognostic favourable (9.64e-5)" "unprognostic (2.75e-2)" "unprognostic (1.98e-2)" "unprognostic (2.68e-2)" "unprognostic (7.54e-2)" "unprognostic (7.75e-2)" "unprognostic (5.06e-1)" "unprognostic (6.39e-3)" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (9.07e-2)" "unprognostic (9.61e-2)" "unprognostic (2.39e-2)" "unprognostic (2.02e-2)" "unprognostic (4.47e-2)" 9.2 7.1 3.4 13.6 2.9 3.9 8.0 3.2 2.3 8.7 48.4 4.1 11.3 19.4 7.4 8.0 13.5 4.9 9.5 4.2 3.1 2.7 12.9 38.6 14.3 9.4 3.5 2.3 6.9 10.5 4.2 5.7 7.7 2.9 6.4 9.8 3.3 22.6 12.0 4.4 8.6 49.3 6.9 4.5 13.8 11.3 8.0 2.7 18.6 16.2 12.9 14.1 7.8 10.3 1.4 1.8 1.5 1.0 0.4 4.1 0.4 11.3 2.0 4.8 5.1 6.5 12.1 11.8 17.1 16.1 15.0 19.2 3.6 12.2 29.4 3.9 12.9 4.7 10.9 8.6 14.9 8.9 3.8 9.4 5.1 9.1 6.2 18.9 7.3 8.1 7.8 5.6 5.9 10.1 6.2 24.7 14.5 4.4 18.2 16.9 8.4 4.6 11.0 18.9 17.1 13.2 8.1 10.1 2.2 8.7 6.9 3.5 9.8 11.0 10.4 10.7 2.7 6.5 11.0 28.4 13.5 22.4 12.5 16.1 10.8 1.5 0.4 0.0 1.3 1.0 0.9 1.4 1.5 1.2 0.3 1.0 1.4 1.3 0.2 0.4 0.9 1.8 4.1 0.4 3.4 2.9 3.2 2.3 3.1 2.7 3.5 2.3 2.9 2.7 PI4KA "PI4K-ALPHA, pi4K230, PIK4CA" ENSG00000241973 "Phosphatidylinositol 4-kinase alpha" P42356 22 20707691-20859417 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.0" "Cell line enhanced" "Detected in all" "K-562: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009092, HPA075515" Approved Approved "Nucleoplasm,Plasma membrane" 18000 Nucleoplasm "Plasma membrane" "CAB009092: AB_2164033, HPA075515: " "unprognostic (8.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.21e-1)" "unprognostic (5.01e-3)" "unprognostic (3.19e-2)" "prognostic favourable (5.24e-4)" "unprognostic (2.08e-1)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.29e-1)" "prognostic favourable (7.22e-5)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (2.35e-1)" "unprognostic (1.50e-1)" 7.7 9.2 28.8 10.5 34.2 12.5 6.5 14.1 48.0 9.7 8.8 10.1 4.9 9.1 9.7 6.1 8.3 8.4 8.0 8.5 30.4 19.2 9.0 12.6 9.0 11.2 19.0 25.9 10.2 8.6 25.6 12.5 10.4 19.3 9.8 8.9 10.8 6.8 10.6 7.1 6.6 10.0 13.2 6.8 10.2 9.9 13.1 8.2 17.9 9.9 2.9 10.2 8.4 4.8 5.0 12.5 7.6 5.5 9.1 7.7 2.9 9.7 8.2 7.3 10.9 20.8 12.6 10.4 8.9 13.5 13.1 12.8 6.4 4.2 18.4 5.3 17.8 8.6 13.8 8.5 8.0 15.6 21.2 18.9 11.2 7.3 10.4 18.7 15.2 11.2 5.4 11.1 6.2 10.6 51.5 15.6 10.1 13.5 16.3 6.4 5.7 8.5 16.4 15.9 3.4 7.3 15.6 17.9 13.1 11.6 13.5 9.2 11.4 8.6 10.7 23.9 12.4 8.8 7.4 12.0 12.2 14.6 15.8 13.5 9.9 3.1 5.5 7.3 5.1 5.4 4.9 4.6 5.6 6.1 3.6 5.0 5.7 7.7 7.6 9.1 4.6 12.5 5.8 2.9 28.8 34.2 14.1 48.0 30.4 19.2 19.0 25.9 19.3 8.2 PI4KB "PI4K-BETA, pi4K92, PIK4CB" ENSG00000143393 "Phosphatidylinositol 4-kinase beta" Q9UBF8 1 151291797-151327715 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006280, HPA006281, CAB022071" Approved Supported "Golgi apparatus" "Golgi apparatus" "CAB022071: , HPA006280: AB_1079613, HPA006281: AB_1079614" "unprognostic (1.17e-1)" "unprognostic (1.57e-1)" "unprognostic (5.42e-3)" "unprognostic (5.23e-3)" "unprognostic (7.32e-2)" "unprognostic (1.36e-2)" "prognostic unfavourable (2.97e-4)" "unprognostic (1.87e-1)" "unprognostic (3.94e-1)" "unprognostic (1.58e-1)" "prognostic favourable (1.25e-5)" "unprognostic (8.51e-2)" "prognostic unfavourable (3.23e-4)" "unprognostic (2.53e-1)" "unprognostic (2.16e-1)" "prognostic unfavourable (6.78e-4)" "unprognostic (7.08e-2)" 25.5 22.2 29.8 21.6 32.3 41.6 27.3 42.6 47.2 30.8 27.1 44.8 26.6 21.8 38.6 35.8 25.6 33.0 25.1 23.8 26.3 22.5 25.6 19.3 27.2 26.2 38.7 28.8 38.6 22.6 41.8 35.5 24.2 29.6 32.2 28.1 28.8 27.1 29.9 36.2 36.9 25.3 39.8 22.7 34.7 23.7 33.1 34.0 26.2 41.2 24.6 28.7 27.1 30.1 17.1 19.7 27.9 20.4 14.7 20.3 17.1 19.3 16.2 14.1 22.1 39.2 29.0 12.0 20.6 36.0 27.0 22.5 20.7 17.6 18.3 23.8 31.5 18.3 23.4 21.2 20.9 24.9 20.8 13.1 19.2 10.6 27.5 15.0 25.3 30.3 25.9 29.9 21.4 26.0 22.3 27.9 22.9 36.0 16.0 12.2 11.3 24.7 14.3 11.9 21.5 18.7 24.6 17.1 14.7 14.3 29.2 18.5 24.6 28.7 20.2 19.4 15.3 15.4 21.9 29.7 19.3 35.8 22.1 15.8 33.5 25.2 17.5 27.9 15.6 20.4 17.4 17.1 16.1 20.3 19.7 15.1 13.6 12.5 17.2 14.7 19.6 11.4 15.9 17.1 29.8 32.3 42.6 47.2 26.3 22.5 38.7 28.8 29.6 34.0 PIAS4 "FLJ12419, Piasg, PIASY, ZMIZ6" ENSG00000105229 "Protein inhibitor of activated STAT 4" Q8N2W9 19 4007646-4039386 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010598 Enhanced Approved Nucleoplasm Nucleoplasm "HPA010598: AB_1079616" "unprognostic (1.23e-1)" "unprognostic (8.94e-3)" "unprognostic (3.50e-2)" "prognostic favourable (1.18e-5)" "unprognostic (2.45e-1)" "unprognostic (4.77e-3)" "unprognostic (4.01e-3)" "unprognostic (9.79e-2)" "unprognostic (6.89e-2)" "unprognostic (6.22e-2)" "prognostic favourable (7.04e-4)" "unprognostic (1.33e-2)" "unprognostic (5.98e-2)" "unprognostic (4.52e-3)" "unprognostic (5.76e-2)" "unprognostic (1.25e-1)" "unprognostic (4.67e-3)" 11.0 9.2 12.4 11.1 16.8 8.6 7.6 22.5 15.7 8.8 11.9 16.7 8.1 13.0 9.5 9.2 9.1 8.4 9.7 6.9 9.7 7.1 7.3 12.4 7.8 10.2 18.2 9.3 11.2 16.0 7.1 9.3 12.9 12.6 9.9 5.4 6.5 14.7 8.7 15.2 12.2 11.2 8.0 12.3 12.0 13.9 38.1 15.9 11.0 6.6 6.3 8.3 8.8 9.8 17.9 11.8 20.2 19.1 16.3 17.3 11.3 10.5 7.6 7.1 6.8 3.5 3.2 11.3 6.4 3.6 6.8 6.2 11.8 4.9 8.0 5.9 3.4 11.1 7.3 5.1 2.9 12.9 11.4 5.7 5.4 9.1 7.2 8.3 10.1 3.7 5.7 6.1 3.8 8.0 10.7 11.1 3.3 10.8 15.1 9.8 15.7 7.0 13.5 7.3 10.4 4.4 5.9 13.0 14.5 9.2 9.0 7.0 8.3 7.7 5.9 6.8 9.8 14.1 10.0 20.8 15.5 10.2 5.7 10.3 8.3 10.5 14.9 20.2 17.3 16.0 12.2 17.9 12.6 15.9 11.8 15.9 11.1 12.5 16.6 16.3 19.1 11.8 13.4 11.3 12.4 16.8 22.5 15.7 9.7 7.1 18.2 9.3 12.6 15.9 PIF1 "C15orf20, FLJ22692" ENSG00000140451 "PIF1 5'-to-3' DNA helicase" Q9H611 15 64815632-64825668 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.3" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 10.2" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "T-reg: 3.2" "Lineage enriched" "Detected in single" 5 "T-cells: 3.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB018701 Supported Supported Nucleoplasm Nucleoplasm "CAB018701: AB_2164654" "unprognostic (1.99e-1)" "unprognostic (6.11e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.62e-1)" "unprognostic (8.33e-3)" "unprognostic (8.66e-4)" "unprognostic (1.47e-1)" "prognostic unfavourable (5.22e-4)" "unprognostic (6.68e-2)" "unprognostic (2.38e-2)" "unprognostic (3.27e-2)" "unprognostic (0.00e+0)" "unprognostic (2.96e-3)" "unprognostic (1.78e-1)" "unprognostic (9.61e-2)" "unprognostic (5.95e-2)" 1.8 1.1 0.6 12.9 0.6 6.0 0.6 0.6 1.2 1.2 5.2 0.6 0.6 3.3 2.0 1.3 4.6 0.8 1.4 0.9 0.6 1.8 0.7 0.6 1.9 7.5 0.9 0.6 0.6 0.6 0.0 0.6 1.4 1.0 2.5 1.8 0.9 0.8 1.2 0.6 1.6 3.7 2.1 0.6 7.0 2.7 3.3 0.6 14.3 0.6 5.1 6.0 1.8 1.9 0.7 0.3 0.0 0.0 0.0 3.2 0.4 5.1 6.0 14.7 5.9 2.6 3.1 5.4 5.1 2.7 5.1 4.0 9.5 8.6 6.2 2.1 2.5 14.3 15.1 4.3 1.9 9.9 5.5 7.2 16.9 6.8 1.3 2.9 5.9 1.7 0.0 2.2 1.8 5.2 4.7 12.5 4.8 4.5 3.0 12.0 12.0 4.2 6.4 4.9 8.7 2.8 2.9 6.1 3.9 3.9 4.3 2.3 4.8 3.1 3.5 3.1 16.1 4.9 9.3 10.1 9.3 5.9 2.9 12.7 4.4 0.0 0.0 0.0 1.5 0.0 0.5 0.7 0.1 1.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.3 3.2 0.4 0.6 0.6 0.6 1.2 0.6 1.8 0.9 0.6 1.0 0.6 PIGA GPI3 ENSG00000165195 "Phosphatidylinositol glycan anchor biosynthesis class A" P37287 X 15319451-15335580 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001174 Approved "HPA001174: " "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.92e-2)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.24e-2)" "unprognostic (7.37e-3)" "unprognostic (3.93e-3)" "prognostic unfavourable (7.64e-4)" "unprognostic (1.85e-3)" "unprognostic (5.97e-3)" "unprognostic (2.24e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-2)" 6.9 6.1 6.8 5.0 8.6 16.1 7.0 7.6 10.0 6.0 6.8 9.6 5.8 3.5 6.2 7.5 9.9 5.6 7.8 6.2 8.0 5.4 7.5 11.0 14.4 5.9 9.6 6.4 7.0 9.9 8.5 5.2 10.8 16.7 5.9 7.5 7.0 11.5 9.1 4.2 10.9 4.8 5.2 10.2 5.7 7.2 5.3 9.4 4.7 8.6 8.5 8.7 11.6 6.6 2.9 3.9 16.7 7.6 1.5 4.4 2.4 12.4 7.7 8.0 4.1 2.4 2.4 6.6 3.2 5.2 7.2 6.9 8.4 5.5 5.8 2.7 2.6 4.9 13.3 10.8 11.8 5.2 9.1 5.0 9.5 4.9 4.1 7.1 2.6 3.4 7.3 9.3 14.8 4.5 5.4 6.3 4.3 7.8 7.9 2.6 4.2 8.6 2.8 11.5 9.2 5.1 8.4 5.6 8.6 6.5 5.9 12.6 6.0 6.2 3.8 5.4 2.2 11.9 6.5 4.8 6.1 9.0 8.3 5.0 6.8 16.7 3.6 3.9 2.7 6.0 3.8 2.9 4.4 2.7 3.9 2.2 4.0 3.1 5.2 1.5 7.6 2.5 3.8 2.4 6.8 8.6 7.6 10.0 8.0 5.4 9.6 6.4 16.7 9.4 PIGC ENSG00000135845 "Phosphatidylinositol glycan anchor biosynthesis class C" Q92535 1 172370189-172444086 "Enzymes, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036663 Uncertain "HPA036663: AB_10669912" "unprognostic (3.35e-1)" "unprognostic (3.01e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-1)" "unprognostic (2.65e-1)" "unprognostic (3.72e-3)" "prognostic unfavourable (4.49e-4)" "unprognostic (7.25e-2)" "unprognostic (2.20e-2)" "unprognostic (4.69e-2)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (1.43e-8)" "unprognostic (1.09e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" "unprognostic (1.90e-1)" 13.8 13.1 10.0 9.0 11.2 14.4 13.9 11.3 12.3 14.4 12.3 9.0 20.9 9.3 14.5 26.1 11.6 15.1 12.1 14.1 8.4 10.2 11.5 12.5 9.0 13.1 12.0 6.6 14.9 16.4 9.2 11.6 14.4 9.6 17.1 12.3 13.2 12.7 15.7 14.8 21.3 15.8 13.5 9.9 12.4 10.5 13.5 9.8 14.2 15.8 10.8 12.3 11.0 10.8 18.9 12.5 27.4 14.5 25.1 33.8 19.2 19.1 16.6 22.6 15.3 17.1 15.6 16.8 12.5 14.1 21.7 19.0 14.8 28.2 10.3 18.5 14.9 20.8 14.6 18.2 17.5 22.8 17.0 12.6 15.8 18.5 19.0 25.8 16.6 23.3 21.9 15.5 17.1 13.7 19.1 19.8 17.4 9.8 19.6 23.2 23.2 23.2 16.2 18.3 18.4 33.3 14.2 11.8 22.5 18.1 21.5 28.2 19.0 18.5 12.5 13.9 23.3 16.9 13.3 13.3 18.8 16.2 9.9 17.0 26.2 27.4 14.5 27.3 19.4 13.5 16.4 18.9 22.7 20.4 12.5 16.7 33.8 24.2 9.5 25.1 14.1 12.4 19.8 19.2 10.0 11.2 11.3 12.3 8.4 10.2 12.0 6.6 9.6 9.8 PIGH GPI-H ENSG00000100564 "Phosphatidylinositol glycan anchor biosynthesis class H" Q14442 14 67581955-67600287 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Autism spectrum disorder, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031624 Approved "HPA031624: AB_10601046" "unprognostic (1.59e-2)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (3.47e-2)" "unprognostic (8.25e-3)" "unprognostic (8.69e-3)" "unprognostic (3.26e-3)" "unprognostic (1.19e-1)" "unprognostic (2.73e-1)" "unprognostic (6.17e-3)" "unprognostic (1.39e-1)" "prognostic favourable (2.68e-7)" "unprognostic (7.42e-2)" "unprognostic (1.42e-2)" "unprognostic (7.00e-2)" "unprognostic (3.73e-1)" 9.7 22.7 15.1 8.8 15.9 18.6 18.5 21.5 18.8 21.8 10.1 11.9 11.5 10.3 10.6 30.6 10.2 9.2 15.6 12.5 14.0 17.2 28.0 18.3 9.1 11.0 19.5 11.3 16.7 21.4 56.0 9.4 17.9 17.8 24.1 9.8 21.0 19.9 17.2 19.5 12.7 12.7 13.1 19.2 11.1 12.2 23.6 14.5 13.5 31.5 7.4 10.5 10.8 10.7 31.8 14.4 24.4 20.4 23.5 29.9 16.8 13.9 9.2 8.8 18.3 19.7 7.6 7.5 7.7 9.5 10.9 10.7 14.7 4.9 9.7 7.8 5.3 10.3 15.5 11.1 12.2 14.4 20.6 10.0 7.8 15.0 15.6 7.4 12.2 11.0 14.3 8.3 12.7 6.9 22.5 6.9 7.9 12.2 10.7 12.2 1.6 24.9 3.6 8.9 5.7 11.6 11.7 11.1 13.3 5.9 11.4 18.9 13.1 7.4 3.5 11.1 14.0 14.3 9.2 13.2 8.5 6.6 8.6 15.7 15.2 17.9 12.6 24.4 23.1 16.6 29.9 29.6 24.4 21.5 12.3 31.8 25.7 24.0 6.0 23.5 20.4 14.4 22.3 16.8 15.1 15.9 21.5 18.8 14.0 17.2 19.5 11.3 17.8 14.5 PIGK "GPI8, hGPI8" ENSG00000142892 "Phosphatidylinositol glycan anchor biosynthesis class K" Q92643 1 77088990-77219430 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056383, HPA057040" Uncertain "Intracellular and membrane" "HPA056383: , HPA057040: " "unprognostic (2.43e-2)" "unprognostic (2.60e-1)" "unprognostic (4.07e-2)" "unprognostic (2.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.15e-1)" "prognostic unfavourable (4.68e-4)" "unprognostic (1.07e-1)" "unprognostic (5.19e-1)" "unprognostic (1.12e-1)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (1.76e-2)" "unprognostic (3.37e-1)" "unprognostic (1.38e-1)" "unprognostic (1.21e-1)" "unprognostic (8.12e-3)" 14.5 17.4 13.8 8.0 20.4 10.2 17.1 14.8 22.9 14.2 11.4 17.4 9.6 9.2 14.6 13.8 10.7 13.0 13.6 20.0 15.4 17.7 25.4 19.0 12.3 10.6 17.7 11.7 13.7 14.1 24.9 23.1 11.2 23.8 15.9 12.9 11.2 11.9 12.9 11.9 7.6 11.6 14.5 19.9 14.7 11.6 9.6 17.2 14.6 22.3 8.1 9.8 12.9 9.4 5.2 7.6 7.6 4.4 8.9 12.8 6.3 5.6 6.6 5.5 7.0 31.9 24.0 9.0 11.5 15.9 12.1 17.4 5.5 5.8 5.0 11.9 20.3 5.1 7.0 9.8 22.1 10.2 7.2 6.7 7.2 5.1 7.1 14.9 6.0 14.4 5.3 12.9 11.2 17.8 8.2 17.1 18.6 3.8 4.7 6.0 4.9 11.1 5.5 16.3 6.3 15.4 4.1 4.7 4.4 10.9 10.0 12.5 4.8 8.5 10.1 19.6 7.7 10.5 11.7 7.8 10.8 5.0 14.5 18.9 7.7 6.9 4.1 7.6 8.3 4.4 8.4 5.2 8.5 7.0 7.6 4.1 10.7 9.5 2.0 8.9 4.2 5.2 12.8 6.3 13.8 20.4 14.8 22.9 15.4 17.7 17.7 11.7 23.8 17.2 PIGL ENSG00000108474 "Phosphatidylinositol glycan anchor biosynthesis class L" Q9Y2B2 17 16217191-16351797 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "GPI-anchor biosynthesis" Hydrolase "Deafness, Disease mutation, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012739 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" "Nucleoplasm, Cytosol" "HPA012739: AB_1855367" "unprognostic (3.07e-2)" "unprognostic (2.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" "unprognostic (7.70e-2)" "unprognostic (6.14e-2)" "unprognostic (9.39e-5)" "unprognostic (1.11e-2)" "unprognostic (1.15e-2)" "unprognostic (1.63e-2)" "unprognostic (6.37e-3)" "prognostic unfavourable (2.57e-4)" "prognostic unfavourable (1.47e-4)" "unprognostic (3.19e-2)" "unprognostic (2.13e-1)" "unprognostic (3.38e-1)" "unprognostic (2.75e-3)" 17.3 12.6 11.1 14.3 18.8 8.6 18.0 14.6 15.6 12.9 13.0 17.6 12.8 17.1 19.8 20.2 12.6 13.1 12.7 8.8 8.5 7.5 11.2 18.5 12.5 12.0 14.5 10.7 16.5 16.5 11.9 18.1 10.3 13.6 14.0 14.4 15.5 14.8 16.3 13.4 20.0 15.8 10.1 9.7 12.3 14.8 11.1 13.6 13.7 15.7 11.1 20.4 10.9 12.3 5.2 7.4 5.5 3.7 5.4 9.3 3.3 8.2 11.8 8.0 6.6 11.5 10.8 3.3 4.6 5.5 7.7 13.8 12.0 10.6 4.0 9.4 4.4 12.1 9.8 5.8 11.1 8.6 25.7 8.0 8.2 14.3 12.3 3.4 5.2 9.1 15.2 13.5 15.4 8.8 9.5 5.1 6.1 8.2 6.2 8.0 3.1 6.1 6.1 6.7 11.6 8.7 4.5 4.2 6.0 4.8 3.4 9.4 3.7 3.1 5.7 7.0 4.3 4.6 13.0 3.6 0.1 6.5 8.8 8.5 4.4 0.0 3.7 5.5 6.5 3.2 5.6 5.2 8.5 5.0 2.7 4.4 9.3 7.5 0.0 5.4 2.4 7.4 6.7 3.3 11.1 18.8 14.6 15.6 8.5 7.5 14.5 10.7 13.6 13.6 PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37059170-37073170 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026921 Uncertain Approved Vesicles Vesicles "HPA026921: AB_1847874" "unprognostic (4.47e-3)" "unprognostic (9.45e-2)" "unprognostic (3.03e-1)" "unprognostic (2.40e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-2)" "unprognostic (1.92e-2)" "unprognostic (5.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-2)" "unprognostic (4.21e-3)" "unprognostic (1.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" "unprognostic (5.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.55e-2)" 20.0 30.3 12.3 7.9 13.4 4.2 18.0 6.9 14.3 13.1 13.8 15.6 23.1 9.9 11.7 60.6 12.5 13.9 15.2 27.8 12.3 15.2 19.0 27.4 14.7 9.9 16.1 9.8 15.0 45.4 23.9 28.9 16.2 17.9 21.3 14.3 16.6 22.2 17.4 25.0 7.0 12.8 24.0 24.8 10.1 14.8 19.3 8.4 16.3 20.3 17.3 9.9 17.2 9.2 18.2 16.7 1.7 11.1 8.7 19.3 8.7 9.5 4.5 9.6 5.8 17.3 11.4 6.4 7.7 14.3 7.0 7.9 6.0 20.2 13.1 17.3 11.6 7.7 7.9 8.8 7.4 13.6 13.8 29.8 5.7 8.3 10.5 8.8 6.5 10.3 16.6 12.6 15.8 12.0 17.7 23.5 15.4 6.3 11.7 9.7 7.3 11.1 11.4 4.9 13.8 17.6 5.3 19.7 11.8 21.8 16.4 29.2 14.0 19.3 6.2 5.2 2.5 6.0 7.0 31.3 34.0 15.0 15.0 11.3 17.0 0.2 7.1 1.7 11.3 10.4 14.0 18.2 14.5 12.1 11.1 15.3 19.3 16.7 1.0 8.7 11.1 16.7 10.7 8.7 12.3 13.4 6.9 14.3 12.3 15.2 16.1 9.8 17.9 8.4 PIGQ "GPI1, hGPI1" ENSG00000007541 "Phosphatidylinositol glycan anchor biosynthesis class Q" Q9BRB3 16 566995-584136 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039105, HPA039828, HPA061414" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" Nucleoplasm "HPA039105: AB_10796221, HPA039828: AB_10795158, HPA061414: " "unprognostic (1.23e-2)" "unprognostic (6.12e-3)" "unprognostic (2.81e-1)" "unprognostic (2.65e-2)" "unprognostic (1.09e-2)" "unprognostic (2.42e-1)" "unprognostic (9.58e-2)" "unprognostic (8.05e-2)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (8.98e-2)" "prognostic favourable (2.53e-6)" "unprognostic (2.73e-1)" "unprognostic (2.60e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" 13.9 15.7 12.8 8.7 13.9 48.4 8.4 12.8 20.6 8.4 9.7 11.4 16.7 15.4 10.9 23.3 7.2 10.0 13.6 7.4 10.5 11.1 18.9 12.5 13.0 6.2 9.1 13.2 10.4 29.3 18.1 15.3 8.4 9.4 11.2 4.1 15.4 15.5 17.6 12.4 12.8 8.1 5.5 7.2 10.3 13.6 15.3 8.2 11.8 18.4 4.2 7.9 9.8 6.7 5.6 10.5 5.9 6.0 5.5 5.3 3.9 8.5 12.9 4.6 6.4 3.0 1.8 8.7 9.0 3.5 3.9 4.2 9.0 8.0 4.5 11.8 2.0 13.7 2.1 4.0 0.8 13.0 18.9 6.9 14.0 6.4 5.8 6.0 6.5 3.2 6.0 6.5 1.3 3.6 15.4 2.6 1.3 11.1 11.1 6.9 6.2 13.3 21.5 3.8 10.4 3.5 3.4 8.3 13.2 10.2 4.7 6.5 10.7 4.1 8.7 6.6 8.4 7.4 6.2 9.9 2.9 3.6 2.2 3.2 6.4 1.2 4.8 3.0 5.3 5.6 4.6 4.4 4.6 5.1 4.9 5.6 5.1 3.1 5.9 5.5 6.0 10.5 4.2 3.9 12.8 13.9 12.8 20.6 10.5 11.1 9.1 13.2 9.4 8.2 PIK3C2A PI3K-C2alpha ENSG00000011405 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha" O00443 11 17077730-17207983 "Enzymes, Predicted intracellular proteins" "Endocytosis, Exocytosis" "Kinase, Transferase" "Cataract, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037641, HPA037642" Uncertain Supported Nucleoplasm Nucleoplasm "HPA037641: AB_10671878, HPA037642: AB_10697081" "unprognostic (2.35e-1)" "unprognostic (2.16e-2)" "unprognostic (3.71e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (6.63e-2)" "unprognostic (2.47e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (1.86e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "prognostic favourable (1.66e-4)" "unprognostic (3.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" 22.3 16.8 17.6 17.2 26.3 9.2 20.0 22.6 17.2 22.1 17.2 13.9 22.2 15.6 20.3 19.2 16.8 18.2 20.2 16.3 14.5 11.6 25.7 16.3 22.2 11.3 17.6 16.1 17.6 14.2 62.9 23.0 23.5 28.5 18.7 14.3 15.2 15.6 27.5 15.4 13.1 17.9 19.5 31.8 17.5 18.3 19.4 18.0 11.4 32.2 9.3 11.5 23.1 20.5 4.4 5.2 6.0 7.2 4.2 4.8 1.6 22.8 10.5 17.6 10.9 12.7 13.0 15.7 14.5 15.7 10.6 14.9 25.4 2.6 6.7 7.2 12.4 15.2 14.0 11.0 19.0 5.7 12.1 4.1 12.7 9.9 13.9 5.2 6.7 10.1 7.8 10.5 20.6 25.3 9.8 6.5 8.2 7.1 2.8 3.2 10.0 8.1 2.9 18.3 4.6 13.2 20.3 10.4 9.2 22.0 9.5 10.2 5.6 5.3 31.5 8.6 12.4 22.2 8.8 2.6 5.8 5.5 10.2 4.9 9.9 4.1 4.1 2.9 4.6 2.5 3.0 3.6 3.7 3.6 5.2 4.4 4.8 2.8 6.0 4.2 7.2 3.7 2.3 1.6 17.6 26.3 22.6 17.2 14.5 11.6 17.6 16.1 28.5 18.0 PIK3C2B "C2-PI3K, PI3K-C2beta" ENSG00000133056 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta" O00750 1 204422628-204494724 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 31.9;RT4: 33.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive B-cell: 7.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030515, HPA050360" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA030515: AB_10670043, HPA050360: " "unprognostic (5.77e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-2)" "unprognostic (3.45e-1)" "unprognostic (2.19e-3)" "prognostic unfavourable (5.42e-4)" "unprognostic (3.35e-3)" "unprognostic (3.57e-3)" "unprognostic (2.72e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (5.36e-2)" "unprognostic (1.26e-1)" "unprognostic (1.75e-1)" "prognostic favourable (1.16e-4)" 12.9 4.5 11.0 16.0 19.3 5.3 11.0 9.1 17.5 7.4 17.0 36.0 9.6 15.5 10.5 5.8 14.6 7.7 14.7 10.7 14.4 9.1 7.6 5.8 18.0 23.9 24.2 11.2 3.9 6.1 4.7 4.3 20.4 14.5 7.3 14.5 6.3 8.0 14.1 20.0 22.6 15.7 11.2 16.2 14.2 20.7 2.4 23.0 31.8 9.8 8.1 23.1 13.1 11.8 7.4 0.3 0.5 0.2 1.6 2.0 0.4 3.2 6.5 5.8 5.3 3.4 0.3 31.9 0.4 1.3 1.3 0.9 3.8 8.5 5.5 1.2 0.7 8.1 3.4 2.3 0.5 3.3 0.9 0.1 12.9 1.4 0.2 1.9 4.2 0.4 2.4 0.3 0.2 8.5 2.0 3.7 0.1 7.2 6.6 5.5 5.3 4.1 7.2 1.4 1.0 1.6 33.3 6.4 3.5 11.5 16.2 3.7 7.2 1.0 0.3 0.2 2.1 0.6 0.1 4.0 1.1 7.2 0.2 2.9 0.8 0.1 0.2 0.0 1.2 0.0 1.0 2.9 1.3 0.8 0.3 7.4 0.7 0.6 0.5 1.6 0.0 0.1 2.0 0.4 11.0 19.3 9.1 17.5 14.4 9.1 24.2 11.2 14.5 23.0 PIK3C3 Vps34 ENSG00000078142 "Phosphatidylinositol 3-kinase catalytic subunit type 3" Q8NEB9 18 41955206-42087830 "Enzymes, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040718 Approved "HPA040718: AB_10793862" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.40e-2)" "unprognostic (3.55e-3)" "unprognostic (6.15e-2)" "unprognostic (3.61e-2)" "unprognostic (6.00e-3)" "unprognostic (1.91e-1)" "unprognostic (2.11e-1)" "unprognostic (1.71e-2)" "unprognostic (3.86e-2)" "unprognostic (6.41e-2)" "prognostic favourable (4.97e-4)" "unprognostic (1.09e-1)" "unprognostic (1.35e-2)" "unprognostic (1.76e-1)" "unprognostic (6.85e-3)" 19.3 24.1 24.0 14.8 28.3 18.5 21.8 48.2 29.6 18.9 15.3 18.2 17.9 11.4 21.1 23.1 18.8 16.8 16.2 17.0 22.9 12.8 21.9 18.2 16.7 16.7 22.6 22.1 23.9 15.1 23.1 33.7 22.2 30.7 17.7 18.3 12.3 21.2 17.7 21.2 20.7 14.6 18.4 27.4 18.5 16.2 22.2 28.0 24.0 20.3 13.0 20.0 18.0 17.8 10.8 9.4 19.2 10.7 11.1 15.7 7.4 7.4 5.2 13.4 10.2 15.7 17.0 8.2 14.9 19.0 12.0 16.3 2.5 3.8 4.6 8.5 15.0 12.4 10.4 8.3 16.7 7.5 7.3 9.7 8.1 10.2 13.1 14.1 10.6 18.5 12.6 11.2 14.7 12.3 9.3 5.9 16.5 2.4 6.2 9.2 9.9 3.9 38.1 10.0 12.0 13.9 8.2 11.8 13.7 4.7 3.6 10.4 5.2 11.8 15.9 16.3 4.7 3.6 6.8 16.1 18.8 5.3 13.5 19.4 8.6 14.5 9.4 19.2 9.3 10.3 10.3 10.8 9.4 11.4 9.4 9.2 12.3 9.1 18.3 11.1 10.7 5.6 15.7 7.4 24.0 28.3 48.2 29.6 22.9 12.8 22.6 22.1 30.7 28.0 PIK3CA PI3K ENSG00000121879 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 3 179148114-179240093 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Phagocytosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009985, CAB017804" Approved Approved Cytosol Cytosol "CAB017804: , HPA009985: AB_1079610" "unprognostic (1.81e-1)" "unprognostic (2.77e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-3)" "unprognostic (6.49e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-3)" "unprognostic (5.21e-2)" "unprognostic (4.50e-2)" "unprognostic (1.16e-2)" "unprognostic (2.48e-1)" "unprognostic (9.74e-2)" "unprognostic (3.82e-2)" 20.1 12.3 13.7 11.5 13.4 25.7 22.4 17.1 24.5 12.9 14.0 5.2 5.7 6.5 15.3 7.9 11.6 11.1 13.2 14.2 18.4 9.7 11.7 10.8 13.2 13.8 9.8 15.7 15.4 9.2 24.7 11.6 16.5 16.3 10.7 8.9 7.2 10.9 10.9 15.2 12.0 10.5 12.8 14.4 16.2 10.6 9.3 9.8 29.6 11.0 7.3 13.9 15.1 15.7 6.2 2.6 7.8 3.8 2.4 5.0 1.1 14.4 4.9 7.9 7.3 18.7 21.8 5.7 9.2 12.5 9.1 14.4 4.2 10.7 13.2 15.8 11.0 5.9 6.4 8.0 13.2 22.0 5.7 18.1 5.3 3.7 8.9 10.1 10.3 13.7 8.5 10.0 11.5 13.0 9.0 14.7 13.0 5.7 7.7 9.1 6.2 6.7 11.8 8.0 15.8 7.2 8.8 4.4 7.6 10.0 8.9 12.0 14.9 8.7 13.8 8.6 5.6 13.5 9.2 7.1 10.1 23.7 7.7 7.6 5.0 2.1 3.8 1.6 5.0 2.9 3.9 5.8 4.2 2.8 2.2 6.2 4.6 3.8 7.8 2.4 3.0 2.6 4.1 1.1 13.7 13.4 17.1 24.5 18.4 9.7 9.8 15.7 16.3 9.8 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652699-138834938 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 41.2;HMC-1: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: " "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavourable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavourable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 12.5 9.9 10.6 9.7 20.6 17.4 11.5 29.9 25.0 12.4 14.6 11.9 11.7 13.7 9.6 6.9 15.2 10.9 8.7 12.7 12.2 14.2 22.6 9.3 9.5 9.1 11.9 15.2 8.8 20.3 20.2 10.9 18.1 24.1 13.4 15.7 12.2 14.9 15.9 33.4 19.6 16.4 8.3 12.5 9.9 11.0 6.4 10.7 14.4 37.4 7.1 11.9 13.4 11.0 4.6 9.1 11.3 7.8 1.3 6.5 2.6 22.6 9.8 4.2 3.5 3.9 5.2 28.7 5.3 5.1 5.4 5.8 10.5 8.6 9.1 14.5 5.2 9.7 5.5 8.4 9.7 11.6 6.2 41.2 6.7 6.3 4.0 10.0 65.3 4.4 6.5 3.8 7.7 8.1 15.7 6.8 6.7 10.3 5.8 7.0 6.0 9.2 4.2 4.4 6.5 8.3 12.5 3.7 2.7 14.7 6.4 18.9 16.0 23.9 8.5 3.5 4.4 7.5 7.4 11.5 7.5 8.3 8.5 9.7 4.8 7.0 7.8 11.3 4.0 4.5 2.7 4.6 5.2 3.0 9.1 4.1 6.5 4.4 10.0 1.3 4.3 1.4 2.2 2.6 10.6 20.6 29.9 25.0 12.2 14.2 11.9 15.2 24.1 10.7 PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9651732-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 35.0;bone marrow: 32.8;lymphoid tissue: 40.3" "Cell line enhanced" "Detected in many" "HDLM-2: 50.5;NB-4: 21.8;REH: 22.7;THP-1: 22.0;U-937: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Cytokinetic bridge" Vesicles "Cytokinetic bridge" "CAB015420: AB_831654, HPA044953: " "unprognostic (5.73e-3)" "unprognostic (2.75e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-2)" "unprognostic (3.46e-2)" "unprognostic (6.75e-2)" "unprognostic (8.65e-3)" "unprognostic (2.09e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.78e-2)" 4.5 2.1 3.4 34.8 7.1 32.8 2.9 3.3 4.3 3.2 3.3 5.5 0.7 3.1 3.7 3.4 3.5 4.0 6.5 2.9 4.2 3.1 4.6 3.3 8.2 40.3 7.4 1.8 5.3 2.2 2.3 2.2 3.3 4.6 3.2 2.1 3.1 11.2 1.8 0.9 2.0 11.4 2.9 5.3 35.5 3.3 3.0 5.7 23.5 4.1 2.3 36.0 5.8 3.6 8.4 14.5 35.0 15.0 14.5 13.7 16.6 2.6 1.7 0.1 0.5 0.4 0.4 0.2 4.1 8.4 9.0 7.4 0.1 1.1 7.1 1.7 3.3 0.8 0.7 3.7 5.7 50.5 0.1 0.8 0.4 3.0 1.8 18.4 6.4 1.5 1.5 10.1 3.4 1.3 2.6 0.0 5.1 0.2 1.7 21.8 0.7 0.5 22.7 4.5 0.2 3.8 0.0 0.5 0.5 0.9 1.7 4.0 0.2 22.0 3.3 2.7 2.8 0.0 3.8 1.6 1.6 10.0 5.8 26.3 1.5 9.6 11.8 21.1 12.9 13.1 13.7 7.8 9.8 11.8 12.5 8.4 12.9 13.4 35.0 14.5 15.0 14.5 7.4 16.6 3.4 7.1 3.3 4.3 4.2 3.1 7.4 1.8 4.6 5.7 PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106907145 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 24.5;bone marrow: 27.8;lymphoid tissue: 40.8" "Cell line enhanced" "Detected in some" "Daudi: 12.2;HMC-1: 15.2;Karpas-707: 12.6;MOLT-4: 23.0;U-266/70: 30.9;U-937: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA069976: " "unprognostic (8.34e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.82e-3)" "unprognostic (3.02e-1)" "unprognostic (6.77e-2)" "unprognostic (1.16e-1)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (9.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.38e-1)" "unprognostic (5.24e-2)" 5.0 1.8 2.2 16.0 3.1 27.8 2.3 0.8 1.7 1.7 4.1 2.7 0.0 2.8 1.7 2.0 2.0 1.8 3.5 1.7 1.7 1.5 1.9 1.5 4.3 13.1 3.0 1.0 1.7 1.5 0.6 1.4 2.0 2.5 2.2 2.6 1.9 3.1 0.5 1.1 1.3 6.1 1.9 6.4 17.4 2.5 7.6 3.0 40.8 2.3 0.9 21.2 4.1 1.5 6.2 5.6 14.2 24.5 5.3 5.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.5 0.0 0.0 0.0 11.9 15.2 0.0 0.0 0.0 0.0 4.7 8.5 12.6 0.0 0.0 23.0 4.6 0.0 0.0 6.1 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 1.2 0.0 0.1 0.0 0.0 30.9 0.0 11.5 0.0 21.8 2.9 4.6 3.4 14.2 5.6 10.6 5.1 4.7 2.6 4.2 5.6 6.2 2.8 3.8 13.9 5.3 24.5 4.9 2.6 3.6 2.2 3.1 0.8 1.7 1.7 1.5 3.0 1.0 2.5 3.0 PIK3R4 "p150, VPS15" ENSG00000196455 "Phosphoinositide-3-kinase regulatory subunit 4" Q99570 3 130678935-130746829 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036032, HPA036033" Approved Approved Vesicles,Microtubules Vesicles Microtubules "HPA036032: AB_10610281, HPA036033: " "unprognostic (7.50e-2)" "unprognostic (3.90e-3)" "unprognostic (1.68e-1)" "unprognostic (4.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (1.02e-3)" "unprognostic (7.26e-2)" "prognostic favourable (4.40e-6)" "unprognostic (8.25e-2)" "unprognostic (3.72e-1)" "unprognostic (2.27e-1)" "unprognostic (1.05e-1)" 15.5 16.2 11.6 11.6 15.9 10.6 14.9 14.7 17.2 16.5 13.1 14.9 9.5 10.3 18.8 12.0 12.9 15.6 12.0 12.2 9.7 10.0 14.9 28.2 13.7 12.4 12.0 11.4 17.8 12.0 40.7 20.6 14.4 17.3 14.1 11.6 14.1 14.0 15.4 14.8 16.0 13.4 14.6 12.1 18.5 13.3 14.9 11.8 29.7 18.1 10.2 13.6 16.5 13.9 8.4 9.6 12.0 8.5 11.5 13.7 7.0 14.1 9.0 13.2 9.5 19.6 15.6 9.2 10.5 12.7 14.6 16.9 11.6 12.1 16.7 13.3 10.6 20.2 21.7 16.4 23.0 10.0 8.0 13.6 10.3 8.0 9.0 20.6 6.8 10.8 11.8 15.5 9.9 13.4 15.7 8.5 12.8 12.4 16.8 6.3 16.6 8.8 11.8 15.4 15.0 9.6 11.6 12.2 8.9 15.1 9.6 10.6 13.2 9.1 10.6 11.2 9.8 12.6 8.4 9.9 9.0 22.0 12.3 7.9 10.4 12.0 7.2 9.2 9.4 8.4 13.7 8.4 8.6 6.9 9.6 5.7 10.1 9.0 6.0 11.5 8.5 3.4 9.3 7.0 11.6 15.9 14.7 17.2 9.7 10.0 12.0 11.4 17.3 11.8 PIKFYVE "FAB1, KIAA0981, MGC40423, p235, PIKfyve, PIP5K, PIP5K3, ZFYVE29" ENSG00000115020 "Phosphoinositide kinase, FYVE-type zinc finger containing" Q9Y2I7 2 208266267-208358751 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Corneal dystrophy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042558, HPA042604" Uncertain Supported Vesicles Vesicles "HPA042558: , HPA042604: AB_10796580" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.88e-1)" "unprognostic (3.03e-1)" "unprognostic (2.04e-2)" "prognostic favourable (6.81e-4)" "unprognostic (6.82e-3)" "unprognostic (6.45e-2)" "unprognostic (1.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.77e-1)" "unprognostic (2.10e-2)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (3.29e-1)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" 15.9 13.5 17.7 21.1 21.9 36.1 24.9 25.6 23.1 14.8 12.1 14.0 16.6 9.1 14.7 18.3 11.2 12.6 11.1 12.5 19.4 14.3 16.2 15.2 16.5 23.1 14.4 15.3 15.6 31.5 21.5 17.0 14.1 20.6 17.7 11.5 13.8 13.7 19.7 13.6 12.9 15.3 13.5 24.4 21.7 12.1 19.3 15.8 23.5 18.2 7.8 22.6 12.4 14.0 7.5 2.1 1.4 1.2 5.6 2.6 0.5 5.0 5.0 12.0 9.3 12.1 14.5 5.6 6.2 12.6 7.3 10.0 7.2 4.2 5.8 6.5 10.6 5.2 10.4 6.9 12.5 4.9 6.6 20.8 9.9 6.4 9.2 18.3 18.8 10.8 7.6 8.5 16.0 11.8 14.0 10.5 9.1 2.1 16.6 13.8 9.9 3.8 6.2 9.3 7.9 9.4 7.3 3.8 9.1 6.8 4.4 12.3 2.8 19.8 13.5 9.2 6.1 6.1 5.7 7.4 8.7 12.4 7.3 16.0 9.0 1.4 1.0 0.7 1.7 0.8 1.1 7.5 2.3 2.6 0.9 5.4 1.8 2.1 1.4 5.6 1.2 2.1 1.5 0.5 17.7 21.9 25.6 23.1 19.4 14.3 14.4 15.3 20.6 15.8 PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170203-37175426 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 34.8;HMC-1: 64.9;U-698: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 64.6" "Group enriched" "Detected in all" 5 "granulocytes: 64.6;T-cells: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoli,Cytosol Cytosol Nucleoli "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavourable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" 39.3 5.4 7.4 18.5 8.9 80.9 20.1 8.1 9.9 23.0 17.9 4.7 4.2 17.9 15.4 9.8 56.3 21.6 24.7 20.8 8.2 3.7 7.5 24.5 14.5 35.7 7.4 2.2 20.0 9.6 2.0 5.6 28.7 12.7 15.6 8.8 6.9 12.8 4.5 26.5 31.3 26.1 31.6 10.7 21.4 12.1 6.8 7.6 15.0 7.2 20.1 28.8 32.6 31.2 1.7 1.4 64.6 1.7 8.4 19.0 8.5 3.0 1.2 2.0 1.1 4.6 2.4 23.5 1.0 3.3 2.2 3.6 4.5 4.2 6.0 1.7 1.2 3.5 2.0 3.2 2.0 27.5 1.3 34.8 1.3 5.8 4.7 0.6 64.9 8.3 4.0 2.0 1.3 0.6 29.9 9.8 0.3 0.7 1.9 3.1 3.7 1.9 4.6 3.6 7.1 0.6 18.4 9.7 1.9 2.3 0.2 0.6 0.5 1.0 1.1 1.3 3.9 5.8 1.3 4.6 2.4 116.6 0.5 8.8 1.3 64.6 1.7 24.4 14.7 1.6 19.0 1.7 13.1 12.9 1.4 1.3 11.9 9.0 14.1 8.4 0.9 0.4 9.4 8.5 7.4 8.9 8.1 9.9 8.2 3.7 7.4 2.2 12.7 7.6 PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 63.4;lymphoid tissue: 71.2" "Group enriched" "Detected in many" 5 "HDLM-2: 58.9;Karpas-707: 73.0;RPMI-8226: 71.9;U-266/70: 133.0;U-266/84: 117.5" "Cancer enriched" "Detected in all" 6 "testis cancer: 171.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol Cytosol "HPA000285: AB_1079619" "unprognostic (2.34e-3)" "prognostic favourable (4.05e-5)" "unprognostic (8.04e-2)" "unprognostic (7.30e-2)" "unprognostic (6.41e-3)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (5.23e-2)" "unprognostic (2.47e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavourable (1.17e-11)" "unprognostic (3.36e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.38e-2)" 3.6 3.4 4.3 37.2 7.2 30.4 3.4 7.1 7.9 4.5 13.4 2.1 2.2 29.5 2.8 4.3 10.0 5.6 8.3 3.1 5.6 6.7 5.2 5.4 10.6 59.7 3.8 4.6 5.4 3.0 1.0 4.9 2.4 6.7 3.6 17.7 6.1 16.9 4.9 1.5 3.0 19.2 2.2 3.1 71.2 14.7 5.7 1.3 39.4 4.8 3.6 47.9 24.6 3.3 26.0 2.9 46.9 3.0 17.0 63.4 13.2 1.8 1.5 0.8 1.6 0.3 0.2 1.2 1.1 1.4 1.6 1.4 1.4 1.3 7.8 0.5 0.5 1.1 2.6 1.0 1.5 58.9 2.1 9.4 1.6 1.4 0.7 2.2 6.4 0.6 0.9 1.6 1.0 0.5 10.0 73.0 0.9 1.3 0.8 4.7 17.8 2.4 1.0 0.5 71.9 1.6 0.2 0.5 0.8 1.2 0.8 0.8 2.0 3.1 0.3 0.3 0.2 0.3 1.1 133.0 117.5 15.0 1.5 2.0 0.3 46.9 1.5 14.3 12.5 1.9 21.2 26.0 34.4 17.6 2.5 15.9 36.9 23.0 38.3 17.0 3.0 2.9 63.4 13.2 4.3 7.2 7.1 7.9 5.6 6.7 3.8 4.6 6.7 1.3 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960513-49964080 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol Cytosol "HPA068758: " "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavourable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favourable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 32.5 15.5 6.8 19.9 16.7 62.4 50.5 7.6 11.9 16.4 22.6 11.3 20.9 15.9 14.4 17.6 25.0 15.9 37.8 23.6 7.5 7.9 29.1 25.7 38.3 29.4 21.1 4.9 13.9 36.4 4.8 14.9 31.4 15.1 28.4 7.6 9.7 27.6 22.7 39.9 31.3 20.9 12.2 10.1 25.4 33.6 13.0 13.5 9.7 19.1 19.9 19.0 25.6 18.3 6.1 5.7 16.9 4.0 1.2 4.5 1.9 7.2 4.8 3.2 6.1 2.5 1.9 18.5 4.6 7.4 5.4 3.9 8.0 6.2 12.9 5.8 1.2 6.2 6.2 3.4 1.9 9.7 25.7 5.3 11.5 9.6 12.0 11.5 10.3 3.6 11.5 3.3 5.7 17.6 7.3 45.7 1.6 16.2 5.8 20.6 6.8 7.7 27.2 5.4 15.3 2.9 5.5 11.6 8.1 8.9 40.6 28.4 5.3 15.3 4.6 3.4 14.8 5.6 7.4 23.5 14.9 11.0 8.6 6.5 9.2 0.0 3.1 0.1 1.9 3.2 2.3 3.4 4.4 3.8 2.5 6.1 4.1 1.7 16.9 1.2 4.0 5.7 4.5 1.9 6.8 16.7 7.6 11.9 7.5 7.9 21.1 4.9 15.1 13.5 PIN1 dod ENSG00000127445 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 1" Q13526 19 9835257-9849682 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 88.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB004528, CAB009326, HPA068650, HPA070887" Approved Enhanced Nucleoplasm,Cytosol 30000 Nucleoplasm Cytosol "CAB004528: AB_628132, CAB009326: AB_2237080, HPA068650: , HPA070887: " "unprognostic (2.54e-1)" "unprognostic (6.14e-3)" "unprognostic (6.50e-2)" "unprognostic (4.36e-2)" "unprognostic (1.71e-2)" "unprognostic (6.50e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (2.67e-1)" "unprognostic (7.23e-3)" "prognostic favourable (3.25e-4)" "unprognostic (9.43e-2)" "prognostic favourable (7.80e-5)" "unprognostic (2.20e-2)" "unprognostic (2.56e-1)" "unprognostic (3.13e-2)" "unprognostic (1.21e-2)" 24.5 36.3 40.0 18.7 38.8 25.6 9.3 27.4 66.0 9.2 15.8 18.1 8.5 22.9 14.0 8.3 11.3 16.4 10.1 25.9 38.0 35.2 17.4 14.5 13.2 14.8 38.7 37.2 13.9 21.1 9.5 13.6 13.3 57.3 23.2 6.5 14.1 21.3 15.7 50.2 10.2 21.7 11.1 19.6 15.4 19.6 24.8 15.0 19.7 9.9 8.1 9.3 11.1 9.7 36.4 72.8 88.2 44.9 40.7 53.8 46.2 25.9 23.8 17.8 16.5 6.2 5.6 10.5 19.4 8.4 14.5 14.0 22.1 8.3 16.1 31.0 7.2 13.3 12.2 11.7 4.6 34.3 52.0 41.8 29.3 19.0 10.1 19.5 24.6 7.6 7.9 9.4 4.4 11.8 18.9 24.5 8.7 18.2 29.5 76.2 17.0 36.6 27.0 18.5 27.0 10.4 12.8 22.4 26.4 18.7 9.4 21.7 12.0 23.4 19.9 20.1 16.1 31.1 31.1 31.6 29.7 21.7 21.5 25.0 24.7 52.2 43.4 88.2 42.0 44.9 39.2 35.6 41.5 42.1 39.7 36.4 33.1 37.2 26.8 40.7 41.7 72.8 53.8 46.2 40.0 38.8 27.4 66.0 38.0 35.2 38.7 37.2 57.3 15.0 PIN4 "EPVH, PAR14, PAR17" ENSG00000102309 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 4" Q9Y237 X 72181353-72302926 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 68.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054483, HPA064504" Approved Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA054483: , HPA064504: AB_2685274" "unprognostic (2.47e-1)" "unprognostic (6.97e-3)" "unprognostic (1.65e-1)" "unprognostic (3.77e-2)" "unprognostic (8.42e-2)" "unprognostic (1.30e-2)" "unprognostic (1.14e-2)" "prognostic favourable (6.37e-4)" "unprognostic (1.56e-1)" "unprognostic (2.13e-2)" "unprognostic (2.49e-1)" "unprognostic (9.54e-2)" "unprognostic (2.09e-3)" "unprognostic (1.92e-1)" "prognostic favourable (2.58e-4)" "unprognostic (3.34e-3)" "prognostic favourable (2.66e-4)" 14.4 11.3 15.0 8.0 14.7 6.1 18.8 10.7 16.2 9.7 9.7 8.4 6.7 9.5 11.6 19.3 8.9 8.7 30.7 11.2 15.2 12.2 15.6 23.2 7.9 7.9 12.9 11.0 12.7 8.1 8.0 9.2 9.8 10.0 10.4 11.1 6.6 30.7 37.1 68.7 7.3 9.6 9.2 12.4 16.7 9.3 4.7 6.9 9.7 12.9 40.1 9.1 7.8 9.2 28.9 26.8 23.4 23.6 22.4 33.4 22.7 15.1 17.8 18.6 12.7 12.8 10.7 9.9 10.4 11.9 12.8 13.1 9.0 11.3 4.6 30.4 10.7 10.8 16.5 18.3 15.8 11.5 37.1 7.8 21.2 23.4 7.1 12.3 6.6 7.2 10.1 13.9 4.8 12.9 13.1 20.2 9.5 18.3 10.7 20.7 13.3 16.1 10.7 14.8 13.4 16.2 10.6 11.9 21.3 12.2 5.7 10.7 8.8 11.2 13.0 5.8 8.9 15.9 7.5 6.9 7.5 7.6 16.7 12.3 6.3 21.9 23.3 23.4 26.8 23.6 26.4 28.9 28.3 25.5 22.8 26.4 29.3 29.4 9.7 22.4 21.8 26.8 33.4 22.7 15.0 14.7 10.7 16.2 15.2 12.2 12.9 11.0 10.0 6.9 PINK1 PARK6 ENSG00000158828 "PTEN induced putative kinase 1" Q9BXM7 1 20633455-20651511 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 142.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 10.7" "Group enriched" "Detected in many" 4 "granulocytes: 10.7;monocytes: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001931, CAB026191" Uncertain "CAB026191: , HPA001931: AB_1079620" "unprognostic (3.73e-3)" "unprognostic (2.29e-2)" "unprognostic (3.22e-1)" "unprognostic (4.33e-2)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" "unprognostic (1.56e-2)" "unprognostic (3.36e-2)" "unprognostic (3.51e-2)" "unprognostic (4.06e-3)" "unprognostic (3.34e-2)" "unprognostic (2.54e-1)" "prognostic favourable (1.11e-16)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (6.57e-2)" "unprognostic (1.08e-1)" 17.9 35.9 38.9 6.7 38.0 6.0 10.1 16.8 45.0 9.8 13.0 17.8 10.0 15.2 9.3 9.8 20.7 10.7 11.4 51.4 31.0 28.7 20.2 26.1 10.0 5.1 39.5 27.1 11.6 24.3 16.3 7.1 13.9 31.0 12.4 7.7 10.6 23.9 15.4 142.0 10.8 12.7 10.8 30.2 8.3 10.5 27.2 16.8 3.3 16.0 21.5 4.6 12.7 9.5 1.2 1.4 10.7 4.4 0.7 1.7 0.8 17.9 8.2 3.8 11.0 13.4 12.7 4.0 25.2 25.4 12.3 21.4 2.8 14.6 4.2 20.0 25.7 8.3 5.6 13.4 6.1 5.0 21.2 2.1 22.9 4.4 10.4 2.2 6.7 11.9 14.5 15.3 5.3 7.9 5.1 5.4 8.8 7.6 3.2 5.1 1.7 27.0 2.8 6.8 3.3 7.6 4.2 14.3 5.6 27.5 9.1 7.6 3.0 7.8 12.0 11.1 5.7 18.5 3.5 6.3 1.2 1.9 24.1 6.5 5.2 4.8 2.2 4.7 1.1 1.4 1.4 0.3 1.0 1.5 0.7 1.2 0.8 1.1 10.7 0.7 4.4 1.4 1.7 0.8 38.9 38.0 16.8 45.0 31.0 28.7 39.5 27.1 31.0 16.8 PIP4K2A "PIP5K2A, PIP5KIIA, PIP5KIIalpha" ENSG00000150867 "Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha" P48426 10 22534849-22714555 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 92.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065440, HPA068771" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" 8800000 "Golgi apparatus" "Plasma membrane, Cytosol" "HPA065440: , HPA068771: " "unprognostic (1.11e-1)" "unprognostic (2.71e-3)" "unprognostic (1.57e-3)" "unprognostic (4.20e-3)" "unprognostic (1.55e-1)" "unprognostic (8.80e-3)" "unprognostic (1.56e-3)" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (7.08e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-1)" "prognostic unfavourable (1.46e-4)" "unprognostic (1.52e-3)" "unprognostic (2.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.92e-3)" 13.0 7.3 43.8 20.3 63.8 17.3 6.9 6.6 41.4 13.2 7.8 75.5 1.0 5.9 9.9 5.6 9.2 7.2 15.1 5.9 56.0 31.7 7.6 8.3 11.5 33.4 65.7 22.9 4.3 4.9 29.5 4.2 10.5 36.5 4.4 9.0 5.7 3.9 6.3 2.6 4.0 8.1 14.4 92.0 26.6 8.4 5.4 59.8 10.1 5.9 1.0 38.5 11.5 5.8 14.7 12.0 26.3 16.6 38.4 46.7 39.3 8.7 8.7 10.1 3.2 16.3 22.2 7.7 16.4 17.5 8.9 11.0 8.1 14.2 18.5 6.0 32.9 3.1 8.8 4.6 9.0 40.9 9.1 34.7 6.4 17.9 28.9 6.6 27.3 11.1 4.1 12.1 11.7 13.1 19.3 36.1 16.4 3.6 26.6 6.0 4.1 6.2 10.7 14.5 25.1 13.2 1.7 1.8 4.3 5.2 2.7 26.1 2.3 11.6 15.8 6.9 10.1 12.7 10.0 23.0 13.0 13.5 18.6 20.2 5.3 16.1 8.8 26.3 34.5 15.6 46.7 14.7 27.5 40.0 11.6 8.6 18.6 34.9 10.9 38.4 16.6 12.0 19.6 39.3 43.8 63.8 6.6 30.3 56.0 31.7 65.7 22.9 36.5 59.8 PIP4K2B "PIP5K2B, PIP5KIIB, PIP5KIIbeta" ENSG00000276293 "Phosphatidylinositol-5-phosphate 4-kinase type 2 beta" P78356 17 38765689-38800126 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 23.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047875, HPA062220" Approved Supported Nucleoplasm Nucleoplasm "HPA047875: , HPA062220: " "unprognostic (7.77e-2)" "unprognostic (8.37e-2)" "unprognostic (3.74e-2)" "unprognostic (1.13e-1)" "unprognostic (2.67e-1)" "unprognostic (1.91e-1)" "prognostic unfavourable (4.54e-4)" "unprognostic (2.64e-1)" "unprognostic (2.33e-1)" "unprognostic (1.50e-2)" "unprognostic (6.10e-3)" "unprognostic (3.79e-1)" "unprognostic (4.82e-3)" "unprognostic (3.38e-2)" "unprognostic (3.22e-1)" "prognostic favourable (1.36e-4)" "unprognostic (2.48e-1)" 5.1 6.5 12.4 3.3 12.9 1.1 5.0 8.8 17.4 6.8 2.7 7.0 4.2 2.2 7.2 5.9 3.5 7.4 3.6 7.1 9.6 4.1 2.2 5.0 4.2 5.4 13.3 13.3 3.0 5.1 2.7 5.4 7.5 5.1 3.2 4.1 3.8 6.5 23.6 5.8 2.3 7.3 4.7 5.1 2.5 2.8 6.5 2.0 4.7 2.2 4.5 3.7 5.9 3.3 3.1 2.4 2.4 3.4 5.0 3.7 5.9 13.1 21.8 22.7 19.1 15.2 4.5 11.1 12.4 14.1 11.5 8.8 5.9 15.2 7.0 19.0 12.8 14.4 9.2 13.6 10.5 9.3 13.2 8.5 13.0 8.7 15.1 8.1 13.3 11.3 11.0 8.1 11.6 11.5 7.2 15.1 4.5 13.8 11.0 12.2 6.1 15.0 21.6 8.3 10.3 7.4 12.2 17.7 11.2 4.6 11.3 14.4 14.3 12.3 11.9 7.9 10.2 9.6 9.5 11.9 6.9 14.1 11.9 10.7 1.6 2.4 0.8 4.8 2.2 5.0 3.1 4.1 4.6 3.1 3.3 4.7 4.2 2.4 3.4 1.8 3.0 3.9 3.7 PIP4K2C "FLJ22055, PIP5K2C" ENSG00000166908 "Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma" Q8TBX8 12 57591174-57603418 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028658, HPA058551" Approved Approved Vesicles Vesicles "HPA028658: AB_10601245, HPA058551: " "unprognostic (7.84e-3)" "unprognostic (1.51e-1)" "unprognostic (2.42e-1)" "unprognostic (2.77e-2)" "unprognostic (2.49e-2)" "unprognostic (3.37e-2)" "prognostic unfavourable (7.98e-4)" "unprognostic (3.17e-2)" "unprognostic (6.00e-2)" "unprognostic (5.51e-2)" "unprognostic (1.75e-1)" "unprognostic (1.88e-1)" "prognostic favourable (2.06e-6)" "unprognostic (1.87e-1)" "unprognostic (2.16e-1)" "unprognostic (3.27e-1)" "unprognostic (3.42e-1)" 9.3 13.3 13.9 9.2 25.9 16.7 15.0 18.9 45.5 12.5 17.5 14.6 15.8 11.6 14.2 62.0 20.0 20.0 12.1 10.8 15.4 10.9 26.9 14.4 14.4 9.2 14.3 21.2 12.3 14.9 29.6 13.7 11.1 18.8 16.7 19.4 17.4 18.6 14.6 9.4 18.4 13.3 11.9 12.7 10.7 27.6 25.6 12.1 5.9 17.9 8.5 13.1 14.6 14.1 6.8 5.4 29.7 8.4 9.4 16.1 6.5 18.8 13.4 5.4 6.5 0.0 0.0 17.5 7.9 14.8 14.3 13.3 16.9 27.3 4.1 17.3 9.2 17.3 8.9 15.5 11.5 6.1 10.0 7.4 6.5 11.9 12.6 6.8 13.3 4.9 26.4 5.4 10.1 7.2 9.5 12.4 7.4 18.6 6.1 5.9 10.3 11.6 0.1 49.2 6.1 15.0 32.4 9.1 11.3 17.0 11.4 10.8 31.1 6.4 1.6 7.2 10.0 10.5 8.3 9.6 11.1 9.2 14.2 5.8 11.9 29.7 5.2 15.3 16.1 6.2 10.7 5.9 9.9 12.0 5.4 6.8 9.6 11.5 10.2 9.4 8.4 2.3 12.1 6.5 13.9 25.9 18.9 45.5 15.4 10.9 14.3 21.2 18.8 12.1 PIP4P1 "C14orf9, MGC26684, TMEM55B" ENSG00000165782 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1" Q86T03 14 20457719-20461612 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048528 Approved "HPA048528: " "unprognostic (1.84e-1)" "unprognostic (6.23e-2)" "unprognostic (1.81e-1)" "unprognostic (7.07e-2)" "unprognostic (2.04e-1)" "unprognostic (8.51e-2)" "unprognostic (1.71e-2)" "unprognostic (3.37e-3)" "unprognostic (4.94e-2)" "unprognostic (1.33e-1)" "unprognostic (7.78e-3)" "unprognostic (1.85e-1)" "prognostic favourable (1.01e-4)" "unprognostic (4.80e-2)" "unprognostic (1.47e-1)" "unprognostic (7.53e-2)" "unprognostic (1.96e-1)" 15.9 16.8 19.7 15.1 24.7 42.2 15.6 23.8 41.0 14.4 19.2 22.9 12.6 17.9 15.6 29.3 16.5 16.4 18.0 15.9 20.2 23.5 18.7 17.7 17.3 16.8 18.9 22.2 15.3 21.1 28.4 20.0 22.6 28.5 16.1 16.5 20.3 16.1 17.2 22.2 22.1 22.1 16.7 17.0 22.0 18.0 13.3 18.5 14.2 17.7 12.8 20.8 17.5 14.0 13.3 10.6 6.9 3.3 4.6 6.6 2.4 11.2 17.8 12.0 13.9 18.8 11.7 22.0 10.7 21.1 14.7 17.9 10.5 18.4 10.2 9.3 13.4 11.9 14.6 11.9 13.1 13.3 10.8 7.3 8.5 15.4 25.7 13.4 15.0 15.1 16.2 17.0 17.4 13.6 6.1 20.7 12.2 12.9 18.2 11.9 8.0 24.5 13.5 11.6 6.7 13.8 25.5 17.3 12.9 11.0 18.2 13.7 9.1 12.7 9.4 13.5 17.2 20.2 9.5 23.4 29.9 14.5 9.3 10.4 14.6 1.3 3.3 6.9 4.7 2.4 4.0 13.3 5.6 5.1 4.1 11.3 6.4 6.6 4.2 4.6 2.0 10.6 4.2 2.4 19.7 24.7 23.8 41.0 20.2 23.5 18.9 22.2 28.5 18.5 PIP4P2 "DKFZp762O076, TMEM55A" ENSG00000155099 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2" Q8N4L2 8 90993796-91041064 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "neutrophil: 36.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 36.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014591 Approved 57000 "HPA014591: AB_1858124" "unprognostic (6.09e-2)" "prognostic unfavourable (1.01e-4)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.54e-4)" "prognostic unfavourable (3.76e-5)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (7.58e-2)" "unprognostic (4.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.25e-2)" "prognostic unfavourable (8.01e-4)" "unprognostic (1.59e-1)" "unprognostic (9.05e-2)" "unprognostic (7.99e-2)" 15.8 18.6 18.7 9.1 19.5 35.2 11.7 21.4 31.7 14.2 16.5 11.1 7.3 4.4 15.0 7.1 8.5 8.6 15.5 26.0 18.2 23.5 13.7 5.7 8.1 11.8 22.8 20.0 16.1 4.8 14.6 13.4 12.2 25.5 12.3 7.2 17.4 10.1 18.6 16.7 8.0 6.6 18.6 25.4 11.2 9.6 9.7 21.1 7.1 9.4 6.9 7.7 13.3 10.5 1.5 5.3 36.2 5.6 1.2 2.4 2.9 2.6 1.6 9.4 5.9 15.3 18.1 1.9 11.4 13.5 5.8 8.6 1.0 4.4 5.1 1.5 10.9 0.6 2.2 3.7 7.6 4.7 4.6 8.1 1.7 0.8 13.8 1.9 7.3 10.0 2.4 7.3 5.4 5.5 4.0 17.0 20.1 1.8 5.4 4.8 4.9 5.9 2.2 3.8 6.1 8.1 1.6 1.0 5.3 0.7 3.6 13.9 0.1 3.3 8.3 10.4 4.3 6.0 4.8 6.8 4.1 3.1 18.0 3.4 13.9 0.3 5.6 5.3 0.8 2.6 1.3 1.5 1.8 0.9 5.3 1.1 2.4 1.0 36.2 1.2 1.0 3.1 1.5 2.9 18.7 19.5 21.4 31.7 18.2 23.5 22.8 20.0 25.5 21.1 PIP5K1A ENSG00000143398 "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha" Q99755 1 151197949-151249536 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029366 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA029366: AB_10602116" "unprognostic (1.05e-1)" "unprognostic (2.36e-2)" "unprognostic (8.64e-2)" "unprognostic (7.94e-3)" "unprognostic (1.17e-1)" "unprognostic (3.28e-2)" "unprognostic (1.26e-2)" "unprognostic (3.01e-1)" "unprognostic (8.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "prognostic unfavourable (4.16e-7)" "unprognostic (1.44e-1)" "unprognostic (8.14e-2)" "unprognostic (2.93e-1)" "unprognostic (1.59e-1)" 18.1 19.5 15.7 15.4 21.0 9.6 20.2 22.6 27.6 19.8 18.0 20.3 14.7 16.4 24.8 22.6 20.7 19.4 20.7 18.9 17.3 13.4 17.8 18.3 21.7 17.1 12.7 17.5 20.4 16.6 21.8 25.3 44.6 14.6 17.3 15.6 29.5 17.8 15.2 26.1 20.4 20.4 27.2 16.1 20.1 16.8 42.1 14.0 19.3 20.1 13.9 22.3 16.2 17.7 9.1 8.7 11.7 6.2 4.7 5.9 6.3 17.7 13.8 21.4 24.6 14.1 14.9 21.0 23.4 33.0 43.8 39.3 25.1 17.2 16.1 25.0 24.9 15.1 27.7 16.1 38.4 24.3 19.8 12.8 18.2 11.9 26.7 22.9 16.2 19.9 14.9 27.2 34.5 17.8 12.5 13.8 22.0 24.8 22.8 11.4 31.7 21.4 22.1 18.7 12.0 22.5 10.3 14.3 19.0 31.6 24.4 20.6 25.5 21.7 17.0 17.4 24.4 16.0 28.1 19.3 32.1 36.4 16.9 6.7 20.8 0.1 5.5 7.3 5.3 6.2 4.1 9.1 5.0 5.9 8.4 4.6 5.4 4.2 11.7 4.7 4.8 8.7 3.9 6.3 15.7 21.0 22.6 27.6 17.3 13.4 12.7 17.5 14.6 14.0 PIP5K1B "MSS4, STM7" ENSG00000107242 "Phosphatidylinositol-4-phosphate 5-kinase type 1 beta" O14986 9 68705414-69009176 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 30.3;HEL: 11.3;Hep G2: 9.2;Karpas-707: 6.4;U-266/70: 11.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "eosinophil: 22.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009687 Uncertain Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA009687: AB_1855391" "unprognostic (2.02e-3)" "unprognostic (1.84e-2)" "unprognostic (3.77e-2)" "unprognostic (2.72e-1)" "unprognostic (1.56e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-3)" "unprognostic (1.80e-2)" "unprognostic (1.38e-2)" "unprognostic (1.17e-1)" "unprognostic (2.98e-2)" "unprognostic (2.92e-2)" "prognostic favourable (1.03e-9)" "unprognostic (2.10e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" 4.0 9.5 9.4 8.4 6.5 10.2 4.2 33.4 14.6 5.6 26.9 4.1 10.8 26.1 6.1 2.0 1.2 5.0 7.6 24.6 8.1 11.7 6.1 0.8 12.6 2.1 10.4 6.4 1.4 6.7 21.3 8.5 16.8 32.8 3.3 23.1 28.7 11.6 13.6 3.0 2.4 39.7 2.6 3.7 3.1 19.9 17.6 1.5 0.0 1.6 1.9 3.3 3.5 2.9 3.9 0.9 22.1 0.3 0.0 1.0 0.2 0.0 0.0 30.3 0.0 0.1 0.0 5.9 0.0 0.0 0.0 0.0 3.2 0.0 2.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 11.3 0.2 9.2 0.0 0.6 2.8 0.0 1.3 0.0 0.0 0.1 0.5 6.4 0.2 0.7 0.0 0.1 1.5 0.9 0.9 0.1 0.1 0.2 2.3 0.6 0.1 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.0 11.7 2.2 1.4 0.0 2.1 0.0 3.1 0.3 22.1 0.0 0.0 0.0 3.3 0.2 0.0 0.1 3.9 0.5 0.0 1.2 0.0 0.1 0.9 1.0 0.2 9.4 6.5 33.4 14.6 8.1 11.7 10.4 6.4 32.8 1.5 PIP5K1C "KIAA0589, LCCS3, PIP5Kgamma" ENSG00000186111 "Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma" O60331 19 3630183-3700479 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Endocytosis, Exocytosis, Phagocytosis" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017168 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA017168: AB_1855395" "unprognostic (1.20e-1)" "prognostic favourable (1.79e-4)" "unprognostic (1.36e-3)" "prognostic favourable (7.28e-5)" "unprognostic (7.03e-2)" "unprognostic (4.02e-3)" "unprognostic (5.80e-3)" "unprognostic (8.50e-2)" "unprognostic (1.31e-1)" "unprognostic (2.57e-3)" "prognostic favourable (2.32e-4)" "unprognostic (1.51e-1)" "prognostic favourable (3.00e-4)" "unprognostic (2.25e-1)" "unprognostic (1.84e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" 16.1 10.2 20.5 12.8 25.8 4.5 8.0 58.6 46.3 10.7 23.5 8.5 14.8 10.9 19.8 10.0 12.3 12.8 12.7 13.8 22.8 10.7 7.5 3.8 11.5 7.5 11.3 17.1 11.5 17.2 10.0 9.2 13.7 19.0 16.7 6.4 16.9 20.0 33.4 13.5 10.2 11.5 19.2 6.3 15.8 13.6 23.9 8.7 5.3 9.3 3.9 6.0 17.3 19.0 2.5 3.2 3.6 3.0 1.7 2.8 2.0 9.0 8.6 6.8 8.8 13.3 10.8 10.2 17.5 11.1 7.5 6.1 7.6 2.6 3.8 6.7 18.8 8.1 3.2 5.6 3.1 13.5 5.7 4.4 7.1 6.2 11.0 4.4 13.5 12.0 5.4 6.1 2.3 12.8 6.6 7.1 7.1 7.5 5.3 3.3 7.0 12.0 10.0 5.2 5.2 5.6 7.8 6.8 5.9 9.1 4.9 5.3 3.9 6.6 28.0 10.6 6.0 37.3 8.1 8.2 6.5 1.7 14.3 9.3 7.6 3.6 2.8 0.0 2.8 2.6 1.2 2.5 2.1 2.0 3.2 1.3 1.0 1.6 2.2 1.7 3.0 2.2 1.4 2.0 20.5 25.8 58.6 46.3 22.8 10.7 11.3 17.1 19.0 8.7 PIP5KL1 "bA203J24.5, MGC46424" ENSG00000167103 "Phosphatidylinositol-4-phosphate 5-kinase like 1" Q5T9C9 9 127920879-127930797 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Karpas-707: 28.9;RPMI-8226: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 1.2;MAIT T-cell: 1.0;memory B-cell: 1.0;myeloid DC: 1.0;naive B-cell: 2.4;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA056240 Uncertain Supported Cytosol Cytosol "HPA056240: " "unprognostic (2.15e-2)" "unprognostic (3.06e-1)" "unprognostic (1.23e-3)" "unprognostic (8.51e-5)" "unprognostic (1.44e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (5.20e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-2)" "unprognostic (1.57e-3)" "unprognostic (9.95e-8)" "unprognostic (1.87e-1)" "unprognostic (7.21e-2)" "unprognostic (6.05e-2)" "unprognostic (1.59e-1)" 0.6 0.7 3.1 0.6 1.0 1.4 2.5 2.4 5.3 2.1 0.6 1.9 0.6 0.5 1.3 0.6 3.7 1.8 1.2 0.6 2.1 2.9 1.3 0.6 2.9 0.6 1.4 2.6 0.7 1.3 6.5 4.8 1.6 8.3 3.3 0.2 1.0 8.7 4.1 0.6 4.7 0.6 1.0 1.5 0.6 2.4 2.5 1.2 0.6 2.9 0.6 0.6 1.2 4.0 2.4 1.3 0.0 1.2 0.0 1.0 0.3 0.0 0.4 0.4 0.5 0.5 1.3 2.7 0.6 0.5 0.1 0.1 0.2 3.5 0.3 1.1 2.3 1.1 0.0 2.6 0.1 0.3 1.7 0.0 0.8 0.0 0.8 0.0 0.1 1.4 1.7 0.3 0.0 0.0 0.0 28.9 0.0 2.4 0.0 1.0 0.2 0.4 0.2 0.0 18.9 0.0 0.0 0.9 1.7 0.1 0.7 0.0 1.0 1.3 0.3 0.3 1.0 0.6 0.1 2.6 1.7 0.6 5.2 0.4 0.3 0.0 0.0 0.0 0.0 1.2 1.0 1.0 0.1 0.0 1.0 2.4 0.2 0.1 0.0 0.0 0.1 1.3 0.0 0.3 3.1 1.0 2.4 5.3 2.1 2.9 1.4 2.6 8.3 1.2 PIR ENSG00000087842 Pirin O00625 X 15384799-15493564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 117.9;SK-MEL-30: 44.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 2.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000697 Approved Supported Cytosol Cytosol "HPA000697: AB_1079621" "unprognostic (3.46e-3)" "prognostic favourable (2.78e-4)" "unprognostic (4.26e-2)" "unprognostic (5.62e-3)" "unprognostic (4.16e-3)" "unprognostic (2.09e-2)" "unprognostic (6.70e-3)" "unprognostic (1.65e-1)" "unprognostic (1.08e-1)" "prognostic favourable (4.94e-4)" "unprognostic (3.78e-2)" "unprognostic (1.92e-1)" "prognostic unfavourable (6.11e-7)" "unprognostic (1.99e-2)" "unprognostic (8.90e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-1)" 20.9 16.1 14.1 5.9 16.8 5.7 26.5 8.5 13.5 8.1 7.5 14.0 21.8 7.7 11.2 18.8 20.7 16.2 13.4 14.0 11.7 12.1 13.9 23.7 18.6 8.6 20.8 9.8 13.0 2.6 5.4 9.1 12.1 15.6 12.1 8.3 25.0 7.5 18.0 9.8 13.7 6.9 24.6 26.0 15.5 13.8 7.2 14.4 1.3 12.1 19.9 9.1 26.5 11.7 0.0 0.5 1.0 0.5 0.0 2.2 0.3 2.3 13.0 7.8 11.5 4.6 5.2 2.5 0.7 4.5 1.9 4.3 3.6 20.4 0.0 25.9 2.0 16.6 9.1 3.6 0.7 0.0 2.0 1.4 14.7 10.5 6.0 0.7 5.2 1.5 12.6 7.3 2.5 117.9 1.0 3.3 1.6 4.9 0.5 0.6 8.4 8.2 0.0 1.5 6.4 3.8 23.0 3.0 8.3 6.3 3.5 44.3 7.3 4.5 7.3 1.0 1.9 4.9 1.4 1.5 6.4 0.0 5.0 2.6 10.3 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.2 0.3 14.1 16.8 8.5 13.5 11.7 12.1 20.8 9.8 15.6 14.4 PISD "dJ858B16.2, PSDC" ENSG00000241878 "Phosphatidylserine decarboxylase" Q9UG56 22 31618491-31662432 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031090, HPA031091" Approved Approved "Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" "HPA031090: AB_10600114, HPA031091: AB_10600893" "unprognostic (7.96e-2)" "unprognostic (5.41e-3)" "unprognostic (2.60e-1)" "unprognostic (8.31e-2)" "unprognostic (5.61e-2)" "unprognostic (4.55e-3)" "unprognostic (2.44e-3)" "unprognostic (8.13e-3)" "unprognostic (6.37e-3)" "unprognostic (1.23e-1)" "unprognostic (1.11e-3)" "unprognostic (1.70e-2)" "unprognostic (4.18e-3)" "unprognostic (1.91e-2)" "unprognostic (4.85e-2)" "unprognostic (3.92e-2)" "prognostic favourable (5.27e-5)" 38.3 12.3 9.5 15.1 10.9 20.9 18.5 34.5 12.3 5.9 7.3 6.2 7.4 11.4 9.6 14.4 7.0 10.0 9.5 6.9 6.4 6.9 11.9 8.4 12.9 14.6 8.3 10.1 7.5 10.9 6.0 11.7 38.1 8.6 8.2 3.3 7.7 7.9 7.9 6.4 10.2 8.0 6.2 5.8 16.5 9.7 17.8 7.7 4.2 10.6 5.3 9.8 6.2 7.0 6.9 11.0 28.6 12.9 5.7 6.8 7.9 10.4 9.6 2.9 2.9 8.9 3.4 6.7 8.5 6.8 6.0 6.5 13.9 3.3 6.3 9.1 4.3 11.8 3.9 7.6 1.0 6.9 8.4 6.6 5.9 11.4 18.5 13.7 17.3 6.4 4.3 10.7 4.6 5.3 19.0 3.7 3.4 39.0 5.9 5.9 2.8 4.0 8.4 3.2 6.3 3.8 9.2 7.2 4.2 4.9 16.0 5.5 13.2 7.5 10.3 7.6 9.0 4.8 7.9 4.5 6.2 7.8 7.2 9.2 6.0 9.9 12.9 9.3 6.8 9.5 6.5 6.9 4.9 5.7 11.0 6.3 6.7 5.5 28.6 5.7 5.0 5.4 4.7 7.9 9.5 10.9 34.5 12.3 6.4 6.9 8.3 10.1 8.6 7.7 PITRM1 "hMP1, KIAA1104, MP1, PreP" ENSG00000107959 "Pitrilysin metallopeptidase 1" Q5JRX3 10 3137728-3172841 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006753, HPA006754" Enhanced Supported Mitochondria Mitochondria "HPA006753: AB_1079624, HPA006754: AB_1079623" "unprognostic (1.83e-3)" "unprognostic (7.01e-3)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (3.20e-2)" "unprognostic (6.67e-2)" "unprognostic (1.55e-1)" "unprognostic (1.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.41e-1)" "unprognostic (1.00e-2)" "unprognostic (3.32e-1)" "unprognostic (7.10e-2)" "unprognostic (3.99e-1)" "unprognostic (5.80e-2)" "unprognostic (4.76e-3)" "unprognostic (2.08e-2)" 26.7 39.4 22.7 20.4 34.4 31.0 21.5 29.7 47.8 21.6 23.4 29.8 19.1 19.1 27.6 27.2 25.0 21.3 23.7 41.0 22.1 19.3 28.8 47.1 23.6 21.2 22.9 25.6 35.3 25.7 31.2 26.0 17.8 38.8 27.2 22.4 29.2 25.1 23.8 62.0 28.0 25.3 26.3 19.1 18.9 21.6 41.6 20.4 48.6 28.7 33.0 26.8 26.0 22.4 11.5 13.7 6.0 13.9 12.4 13.9 9.1 25.4 20.6 8.2 11.1 23.3 25.3 9.4 37.8 17.6 30.2 16.5 18.6 15.6 12.8 13.2 23.6 19.7 13.1 29.2 22.8 22.1 18.7 18.1 16.9 13.9 13.3 7.0 21.6 20.8 21.7 33.0 18.9 31.4 18.3 16.9 39.9 22.0 17.6 7.3 5.6 25.1 8.7 11.4 18.2 24.0 19.5 10.5 6.4 28.6 21.0 15.9 24.4 8.4 38.5 23.9 6.7 58.4 18.1 13.6 14.2 13.3 36.5 12.9 11.7 6.0 9.4 4.9 13.1 12.0 12.9 11.5 11.3 12.2 13.7 6.8 12.1 13.9 1.4 12.4 13.9 7.6 13.8 9.1 22.7 34.4 29.7 47.8 22.1 19.3 22.9 25.6 38.8 20.4 PJA1 "FLJ11830, RNF70" ENSG00000181191 "Praja ring finger ubiquitin ligase 1" Q8NG27 X 69160851-69165793 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 98.7" "Cell line enhanced" "Detected in many" "HAP1: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000595 Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA000595: AB_1079826" "unprognostic (3.40e-2)" "unprognostic (2.28e-1)" "unprognostic (4.03e-2)" "unprognostic (2.58e-3)" "unprognostic (5.44e-2)" "unprognostic (1.30e-2)" "unprognostic (1.26e-3)" "unprognostic (4.61e-2)" "unprognostic (3.82e-3)" "unprognostic (1.84e-2)" "unprognostic (6.10e-2)" "unprognostic (1.60e-1)" "prognostic favourable (7.44e-5)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.10e-1)" 12.6 9.9 21.6 5.5 35.7 2.6 7.9 13.4 23.7 12.2 5.8 8.9 19.3 4.7 9.2 98.7 5.7 10.2 7.1 7.5 18.4 23.4 7.5 4.4 7.4 5.9 14.9 16.7 16.2 6.0 27.1 12.5 10.7 11.7 9.9 5.3 7.2 6.4 20.3 4.7 7.1 4.4 9.8 12.0 5.9 6.5 13.7 9.5 3.0 13.8 2.9 7.4 7.8 7.9 11.2 4.3 2.7 4.5 14.8 17.8 9.0 10.4 8.0 25.1 17.5 8.8 9.3 7.5 7.0 8.4 6.6 8.9 6.5 9.9 1.6 10.9 11.0 9.1 38.5 13.6 8.3 7.8 13.7 3.1 6.6 4.3 11.0 1.8 6.0 9.7 9.1 11.2 6.7 7.4 2.9 1.1 6.7 5.6 0.8 3.5 17.1 13.1 7.5 11.2 2.5 10.6 8.8 18.6 12.1 11.2 1.9 8.5 3.1 2.6 6.7 5.7 9.2 16.9 3.2 0.0 0.1 3.8 6.2 5.1 7.6 2.7 3.3 1.0 15.5 4.5 17.8 8.7 13.7 14.2 3.6 11.2 14.4 16.6 1.1 14.8 2.9 4.3 8.3 9.0 21.6 35.7 13.4 23.7 18.4 23.4 14.9 16.7 11.7 9.5 PJA2 "KIAA0438, Neurodap1, RNF131" ENSG00000198961 "Praja ring finger ubiquitin ligase 2" O43164 5 109334709-109409994 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040347, HPA057636" Supported Enhanced "Intermediate filaments" "Intermediate filaments" "HPA040347: AB_10795631, HPA057636: " "unprognostic (5.78e-2)" "unprognostic (1.25e-1)" "unprognostic (5.48e-3)" "unprognostic (1.17e-1)" "unprognostic (2.99e-1)" "unprognostic (7.83e-2)" "unprognostic (2.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.84e-2)" "prognostic unfavourable (8.02e-4)" "unprognostic (4.46e-2)" "unprognostic (6.03e-2)" "unprognostic (5.64e-3)" "unprognostic (1.47e-3)" "unprognostic (5.94e-2)" "unprognostic (7.59e-2)" "unprognostic (1.00e-2)" 21.6 27.0 40.1 15.9 49.9 29.0 22.1 41.6 63.0 29.0 23.8 19.7 16.8 12.5 29.2 25.0 20.7 20.3 18.6 24.4 44.3 46.2 24.1 29.2 19.4 14.3 36.8 44.0 35.4 14.8 42.8 30.3 21.8 53.2 31.7 20.6 12.5 17.3 37.7 17.1 13.6 15.9 39.2 37.6 19.5 15.8 17.0 27.4 16.7 35.9 9.7 16.3 35.5 21.4 10.3 11.7 29.9 15.5 10.7 12.2 10.6 11.8 8.2 33.1 25.4 32.9 36.1 18.0 19.4 29.4 15.4 25.3 7.6 16.1 15.2 27.0 37.3 6.9 19.3 24.0 28.3 12.9 7.3 17.5 16.8 10.2 23.3 13.1 26.2 24.8 20.1 20.6 29.6 24.5 12.0 28.7 24.8 7.2 15.7 12.1 6.6 5.5 10.2 29.1 25.3 24.0 10.6 6.3 16.3 20.0 7.3 23.4 16.5 19.4 28.2 21.9 10.7 20.2 9.1 19.4 16.5 18.0 23.2 18.3 14.4 17.3 11.6 17.3 9.5 12.2 9.4 10.3 9.4 8.7 11.7 7.4 12.1 8.9 29.9 10.7 15.5 4.9 12.2 10.6 40.1 49.9 41.6 63.0 44.3 46.2 36.8 44.0 53.2 27.4 PKDCC "SgK493, Vlk" ENSG00000162878 "Protein kinase domain containing, cytoplasmic" Q504Y2 2 42048020-42058528 "Enzymes, Predicted secreted proteins" "Differentiation, Osteogenesis, Protein transport, Transport" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 30.5;ASC diff: 24.2;CACO-2: 36.1;HHSteC: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026427, HPA026442, HPA026526" Approved "Secreted to blood" 10000 "HPA026427: AB_10600773, HPA026442: AB_10601237, HPA026526: AB_10602416" "unprognostic (6.77e-2)" "unprognostic (3.35e-1)" "unprognostic (1.04e-2)" "unprognostic (3.59e-3)" "unprognostic (8.31e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-2)" "unprognostic (5.79e-3)" "unprognostic (1.04e-2)" "unprognostic (1.32e-1)" "unprognostic (3.20e-1)" "unprognostic (6.09e-2)" "unprognostic (2.14e-2)" "unprognostic (9.08e-2)" "unprognostic (2.62e-1)" "unprognostic (4.73e-3)" "unprognostic (2.58e-3)" 21.4 5.7 1.9 8.4 1.8 0.8 18.9 0.3 4.7 20.8 13.7 1.7 6.3 9.3 17.6 16.0 9.2 10.0 29.6 17.0 2.3 0.7 4.7 3.5 8.0 3.7 3.7 0.3 43.6 3.3 0.9 3.2 3.2 2.6 13.0 5.2 17.0 38.6 5.6 40.2 1.7 7.7 26.2 2.3 4.6 4.8 14.1 2.3 4.2 3.1 13.1 2.1 22.8 23.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.9 5.4 30.5 24.2 0.3 1.9 0.1 0.0 0.4 0.6 36.1 0.0 0.0 0.1 0.6 0.0 0.5 0.0 0.0 2.9 1.2 0.0 1.3 9.5 20.8 0.0 0.4 2.1 0.1 0.0 0.0 0.2 0.4 0.0 0.1 0.1 0.0 0.1 8.9 0.6 0.0 10.5 0.0 0.0 0.0 1.1 1.9 0.5 0.0 0.0 0.0 0.2 0.0 0.2 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 0.3 4.7 2.3 0.7 3.7 0.3 2.6 2.3 PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301434 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 17.2;kidney: 12.4;liver: 47.8" "Cell line enriched" "Detected in some" 9 "K-562: 47.4" "Cancer enriched" "Detected in some" 9 "liver cancer: 56.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.7" "Low region specificity" "Detected in some" "HPA006653, CAB034376, CAB034378" Enhanced Approved "Golgi apparatus,Cytosol" 2900000 "Golgi apparatus, Cytosol" "CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: " "unprognostic (9.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.62e-1)" "unprognostic (7.86e-4)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-1)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (6.21e-3)" 0.1 0.0 0.1 0.3 0.1 7.2 0.1 0.9 0.2 0.1 4.9 0.1 0.1 5.8 0.1 1.3 0.1 0.0 0.7 0.1 0.1 0.4 12.4 47.8 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.6 17.2 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.2 0.1 0.4 0.1 0.1 0.1 0.1 PKM "OIP3, PK3, PKM2, THBP1" ENSG00000067225 "Pyruvate kinase M1/2" P14618 15 72199029-72231822 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 541.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019421, HPA029501" Uncertain Enhanced Cytosol 540000000 Cytosol "CAB019421: AB_2252325, HPA029501: AB_10602118" "unprognostic (8.73e-3)" "unprognostic (4.63e-3)" "unprognostic (1.68e-2)" "unprognostic (3.09e-1)" "unprognostic (6.51e-2)" "prognostic unfavourable (1.30e-4)" "prognostic unfavourable (2.74e-6)" "prognostic unfavourable (2.85e-4)" "unprognostic (9.51e-2)" "unprognostic (1.17e-2)" "prognostic unfavourable (5.17e-5)" "unprognostic (3.16e-1)" "unprognostic (3.22e-1)" "unprognostic (7.85e-2)" "unprognostic (3.17e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-2)" 23.2 76.8 53.8 49.8 70.4 57.5 41.6 56.6 85.9 65.7 31.2 32.1 31.5 26.4 24.7 41.8 76.4 37.9 32.9 94.8 50.1 57.1 60.9 6.1 33.3 39.4 62.5 63.6 26.2 15.6 33.3 28.3 27.1 80.5 34.8 31.9 54.4 47.1 47.5 541.2 51.8 25.1 44.7 34.9 30.7 26.7 29.0 29.4 23.5 23.8 114.4 60.6 53.1 40.9 25.1 79.6 14.9 90.6 11.6 37.4 114.9 81.5 209.8 42.3 50.0 50.9 57.2 35.0 88.5 206.7 142.1 143.9 59.0 100.5 62.1 89.6 165.6 118.9 133.7 180.0 111.4 109.0 63.2 38.0 105.5 48.8 35.5 49.3 82.0 51.9 83.9 109.5 45.0 83.6 9.5 49.8 224.1 50.7 18.4 21.2 52.3 80.1 54.7 135.4 118.3 188.7 105.0 44.0 48.0 115.4 71.2 90.5 49.9 35.9 65.1 161.9 88.6 158.2 160.5 64.0 90.4 54.7 199.3 81.6 158.6 12.6 90.6 14.9 23.5 52.6 22.8 25.1 31.3 23.2 79.6 16.1 27.3 20.2 11.8 11.6 40.2 16.2 37.4 114.9 53.8 70.4 56.6 85.9 50.1 57.1 62.5 63.6 80.5 29.4 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980539 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 19.5;lymphoid tissue: 42.8;testis: 61.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 5 "T-reg: 4.4" "Lineage enriched" "Detected in single" 5 "T-cells: 4.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: " "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavourable (8.33e-4)" "prognostic unfavourable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 0.9 0.7 0.7 9.4 0.6 19.5 1.3 2.6 0.8 1.3 2.9 0.3 0.5 1.9 0.8 1.5 7.2 0.2 1.5 1.4 0.7 0.7 0.8 1.0 1.3 6.2 0.8 0.2 0.3 1.3 0.0 0.7 4.3 0.4 0.6 0.8 0.3 1.3 0.2 1.6 3.4 3.2 0.6 1.0 4.4 2.7 61.4 0.2 42.8 0.3 9.2 12.7 0.7 2.0 0.8 0.4 0.3 0.5 0.4 4.4 1.0 24.6 17.3 6.8 9.7 0.1 0.3 18.3 19.2 4.6 12.2 11.7 13.4 14.7 15.4 8.6 2.1 31.7 4.7 6.1 2.2 19.8 15.6 7.8 15.6 11.7 0.0 8.7 22.3 0.2 0.5 7.2 1.9 2.5 22.4 27.4 3.9 37.0 24.4 24.2 11.1 9.2 26.6 15.1 29.8 2.3 5.4 12.9 13.6 9.3 24.2 7.2 13.8 17.4 2.3 16.4 20.8 23.9 20.0 20.8 15.4 26.5 6.2 11.7 19.0 0.0 0.4 0.3 0.3 0.3 0.0 0.8 0.5 0.5 0.4 0.0 0.0 0.0 0.1 0.4 0.5 0.1 4.4 1.0 0.7 0.6 2.6 0.8 0.7 0.7 0.8 0.2 0.4 0.2 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 28.8 19.5 19.1 27.6 26.7 39.6 25.3 21.9 19.2 19.2 26.0 20.9 16.5 10.0 25.4 19.7 16.6 22.2 22.5 38.3 17.1 17.6 17.9 16.3 27.9 42.2 19.5 16.3 21.7 32.3 15.8 18.7 22.7 19.2 22.6 6.9 21.5 22.6 22.7 43.2 7.6 16.9 22.5 19.4 39.7 24.2 21.5 18.9 39.2 17.8 13.8 24.0 22.1 30.5 11.5 17.0 24.1 30.6 13.5 20.7 15.2 37.2 22.2 8.3 17.2 13.4 15.8 13.7 13.4 16.1 14.2 13.6 8.6 21.4 35.6 34.8 23.0 8.6 13.2 6.0 5.5 28.8 17.1 42.6 14.2 18.4 44.5 16.7 26.8 11.4 4.3 8.6 13.5 32.9 18.8 24.7 10.4 15.3 25.2 15.5 15.0 25.4 33.9 11.3 25.6 7.0 6.1 30.2 42.8 8.3 10.6 21.7 9.6 29.2 49.2 28.3 12.1 34.1 20.3 32.5 29.6 19.4 18.5 33.6 22.1 15.4 17.3 24.1 20.7 24.2 15.7 10.7 14.0 14.2 17.0 11.5 13.1 14.3 21.3 13.5 30.6 11.1 15.9 15.2 19.1 26.7 21.9 17.3 17.1 17.6 19.5 16.3 19.2 18.9 PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "neutrophil: 35.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: , HPA057913: " "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favourable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" 21.9 20.7 12.2 21.2 13.7 33.5 27.6 25.6 16.6 28.6 39.3 12.6 15.1 22.9 20.0 20.2 28.2 17.1 13.3 16.2 10.3 8.9 15.9 15.9 26.0 16.4 13.7 8.7 27.2 18.9 24.6 29.7 20.8 13.3 19.6 23.6 14.1 19.5 25.1 15.9 17.5 49.0 17.5 12.5 18.0 15.9 12.4 16.2 29.1 20.3 14.4 13.1 21.9 22.0 4.0 3.7 35.7 4.5 1.4 3.0 1.0 23.3 9.2 18.2 10.9 12.2 13.9 11.8 13.8 12.8 15.6 16.2 9.7 16.8 9.2 16.5 13.1 18.4 17.7 10.5 21.3 3.3 12.9 6.8 19.0 8.3 10.7 6.7 2.0 11.4 11.0 12.2 14.8 17.7 11.3 6.7 16.7 4.7 7.7 5.8 9.1 10.7 7.4 27.7 3.8 13.8 46.0 8.8 5.8 20.7 12.0 17.8 8.9 6.1 16.5 13.2 11.9 16.9 14.4 3.7 3.2 6.3 5.5 6.6 5.0 4.9 4.5 6.8 2.6 2.5 2.3 3.3 2.3 2.4 2.1 4.0 3.0 2.6 35.7 1.4 3.2 3.7 1.8 1.0 12.2 13.7 25.6 16.6 10.3 8.9 13.7 8.7 13.3 16.2 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702523-128720918 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 32.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045390, HPA058305" Uncertain Approved Vesicles Vesicles "HPA045390: , HPA058305: " "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 11.4 1.8 1.5 6.8 3.8 3.7 10.5 10.1 3.9 4.3 5.8 3.7 4.8 7.7 9.7 2.2 7.1 5.3 10.9 7.3 2.3 1.7 5.0 6.4 8.9 9.1 3.9 1.2 4.0 4.2 3.3 1.4 5.6 4.5 4.2 1.6 4.1 12.9 3.7 7.4 6.7 5.4 4.9 4.4 7.8 7.4 4.3 1.7 9.3 8.1 6.1 5.9 4.4 5.0 0.4 1.0 2.3 0.7 1.0 1.8 0.3 1.3 6.7 5.5 8.3 0.0 0.1 13.6 4.2 1.3 6.2 6.4 0.0 4.9 0.0 4.1 2.2 9.1 6.7 1.0 1.4 4.2 12.6 8.0 32.8 9.6 1.0 1.0 1.4 0.3 0.3 3.3 0.9 12.2 18.3 0.9 1.1 12.6 1.2 4.3 5.1 2.0 19.9 10.4 1.8 2.6 0.8 0.9 4.1 3.1 1.7 3.1 5.9 6.4 10.5 0.0 5.2 9.7 3.1 3.0 1.3 2.6 0.7 1.0 3.8 0.0 0.1 1.4 0.9 0.7 1.8 0.2 0.6 0.8 1.0 0.4 0.8 0.1 2.3 1.0 0.2 0.2 1.0 0.3 1.5 3.8 10.1 3.9 2.3 1.7 3.9 1.2 4.5 1.7 PLA2G10 GXPLA2 ENSG00000069764 "Phospholipase A2 group X" O15496 16 14672545-14694669 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.4;stomach 1: 13.0" "Cell line enhanced" "Detected in some" "BEWO: 2.7;CAPAN-2: 4.5;SK-BR-3: 2.8;U-266/84: 2.3" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041893 Uncertain "Secreted in other tissues" "HPA041893: AB_10794495" "unprognostic (8.44e-3)" "unprognostic (2.37e-1)" "unprognostic (6.72e-2)" "prognostic favourable (5.74e-5)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (5.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.77e-2)" "unprognostic (2.72e-1)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.08e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-2)" "unprognostic (9.97e-3)" 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.3 9.4 2.4 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 13.0 2.1 0.0 0.0 2.8 0.0 0.9 0.5 2.0 0.5 0.1 0.4 0.1 0.1 1.0 0.1 0.2 0.0 0.1 2.7 0.2 0.0 0.0 0.0 0.7 4.5 0.4 0.5 0.0 2.2 0.0 0.0 0.0 0.2 0.1 0.4 0.4 0.0 0.1 0.8 0.9 0.0 0.1 0.0 0.1 0.0 0.2 0.7 0.0 2.1 0.4 0.3 0.4 0.1 0.8 0.3 0.2 0.0 0.3 0.6 0.5 1.1 2.8 0.4 0.5 0.4 0.9 0.0 0.3 0.1 0.0 0.8 2.3 0.7 0.7 0.1 0.1 0.1 0.5 0.5 0.3 0.4 0.3 0.1 0.2 0.4 0.5 0.9 0.3 0.3 2.0 0.1 0.3 0.3 0.1 0.1 PLA2G12A PLA2G12 ENSG00000123739 "Phospholipase A2 group XIIA" Q9BZM1 4 109709989-109730077 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035908, HPA035909" Approved "Secreted to blood" "HPA035908: , HPA035909: AB_10672074" "unprognostic (8.40e-2)" "unprognostic (3.87e-1)" "unprognostic (3.81e-3)" "unprognostic (3.09e-2)" "unprognostic (2.10e-1)" "unprognostic (1.35e-1)" "unprognostic (4.26e-2)" "unprognostic (1.77e-1)" "unprognostic (1.90e-1)" "unprognostic (2.71e-3)" "unprognostic (1.02e-1)" "unprognostic (8.42e-2)" "prognostic favourable (2.54e-9)" "unprognostic (3.10e-1)" "unprognostic (1.39e-1)" "unprognostic (9.16e-3)" "unprognostic (3.64e-2)" 9.8 9.9 13.1 4.4 16.2 5.6 12.9 14.5 14.3 9.6 12.2 13.4 7.3 11.9 8.9 8.2 12.6 9.2 9.2 21.0 13.0 11.4 15.3 20.6 7.8 4.9 16.8 11.7 11.9 38.8 22.8 19.0 10.4 12.7 16.4 12.0 10.7 12.1 8.3 21.1 9.8 16.3 8.1 20.3 5.5 10.0 5.7 12.4 4.9 19.0 9.2 6.2 7.5 7.7 4.9 8.7 3.6 4.6 4.9 10.2 13.8 9.6 3.6 2.8 4.2 9.0 9.1 5.6 9.0 7.1 5.0 5.3 8.9 17.1 14.0 6.8 6.5 5.4 8.7 11.6 7.8 5.2 13.5 4.9 10.5 5.4 9.0 10.7 3.5 9.2 13.5 5.1 12.7 5.1 27.2 6.5 8.6 17.1 8.7 4.8 5.0 14.1 5.3 8.5 11.0 9.4 14.4 18.3 6.0 7.9 20.8 6.7 12.5 2.3 6.0 7.4 6.1 7.6 6.1 11.0 19.8 10.3 8.3 6.3 9.1 3.6 4.6 2.7 7.2 2.9 6.6 4.2 9.0 6.9 8.7 4.9 10.2 9.2 2.2 4.9 4.4 7.6 8.7 13.8 13.1 16.2 14.5 14.3 13.0 11.4 16.8 11.7 12.7 12.4 PLA2G16 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754." ENSG00000176485 "Phospholipase A2 group XVI" P53816 11 63573195-63616883 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.6" "Cell line enhanced" "Detected in many" "A549: 32.3;ASC diff: 36.7;CAPAN-2: 59.1;HAP1: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 52.4" "Group enriched" "Detected in many" 5 "dendritic cells: 52.4;T-cells: 16.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058997 Uncertain Uncertain Mitochondria Mitochondria "HPA058997: " "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavourable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favourable (2.54e-5)" "unprognostic (2.35e-1)" 113.6 15.2 32.0 4.4 39.4 1.6 33.9 4.8 30.2 6.1 7.2 46.6 6.1 4.0 5.0 11.5 5.9 13.9 12.9 39.0 37.6 25.2 24.7 28.9 13.5 4.5 58.4 22.2 30.9 13.2 15.1 8.1 16.2 30.5 5.9 3.7 8.8 10.1 13.2 37.8 2.4 7.5 8.0 70.4 6.4 10.2 17.8 48.9 0.1 17.1 11.1 2.3 8.0 4.7 2.1 52.4 0.4 6.2 5.3 16.0 6.4 20.4 32.3 0.9 0.0 36.7 6.3 5.9 0.7 6.5 5.4 2.7 7.3 59.1 0.0 13.6 1.6 1.0 30.6 1.6 4.1 25.2 1.2 0.3 7.8 1.2 21.9 0.0 0.3 3.8 0.1 13.5 0.5 8.5 0.3 2.3 5.7 3.5 0.0 0.1 2.6 10.4 0.0 0.0 2.0 17.1 2.9 0.4 2.4 4.4 12.4 6.7 26.9 1.0 12.5 2.4 0.1 8.2 1.8 9.7 6.3 0.0 9.8 0.0 0.2 0.0 6.2 0.0 16.0 2.4 8.8 2.1 3.7 11.6 1.7 0.3 1.2 9.4 0.4 5.3 0.1 52.4 2.4 6.4 32.0 39.4 4.8 21.9 37.6 25.2 58.4 22.2 30.5 48.9 PLA2G1B "PLA2, PLA2A, PPLA2" ENSG00000170890 "Phospholipase A2 group IB" P04054 12 120322111-120327789 "Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 933 "pancreas: 2360.6" "Cell line enhanced" "Detected in some" "EFO-21: 2.2;Hep G2: 6.3;U-2 OS: 4.6" "Cancer enriched" "Detected in many" 185 "pancreatic cancer: 763.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.5" "Group enriched" "Detected in many" 19 "NK-cells: 1.3;T-cells: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047822, HPA060803" Enhanced "Secreted to digestive system" 3900000 "HPA047822: , HPA060803: " "unprognostic (1.28e-4)" "unprognostic (6.02e-2)" "unprognostic (1.84e-2)" "unprognostic (2.86e-2)" "unprognostic (2.74e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (3.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (2.80e-4)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (3.60e-1)" "unprognostic (8.61e-4)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 1.1 0.1 0.1 0.1 1.1 2360.6 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.3 2.5 0.9 0.2 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.5 0.0 0.3 1.3 0.3 1.6 0.0 0.0 0.2 0.0 0.6 0.0 1.0 0.2 4.6 0.6 0.6 0.0 1.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.3 0.0 0.0 2.5 0.9 0.0 1.3 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PLA2G2A "PLA2B, PLA2L" ENSG00000188257 "Phospholipase A2 group IIA" P14555 1 19975431-19980416 "Enzymes, FDA approved drug targets, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 377.9" "Group enriched" "Detected in some" 14 "Hep G2: 34.2;RT4: 31.4" "Cancer enhanced" "Detected in all" "prostate cancer: 875.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA015236 Enhanced "Secreted to blood" 1000000 290000 "HPA015236: AB_10601047" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (2.79e-2)" "unprognostic (7.85e-3)" "unprognostic (8.71e-2)" "unprognostic (9.27e-2)" "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "prognostic favourable (1.49e-4)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.77e-15)" "unprognostic (2.72e-2)" "unprognostic (9.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.51e-1)" 25.2 1.0 0.0 13.1 0.0 0.6 14.0 0.0 0.6 1.4 63.9 0.0 0.1 35.0 0.7 22.7 31.5 11.7 2.4 105.4 0.0 0.0 1.6 377.9 3.0 6.5 0.0 0.0 35.6 2.4 0.6 0.5 15.5 0.0 27.1 68.2 6.1 9.5 1.0 30.6 5.0 99.0 39.7 0.0 0.6 4.0 9.8 0.0 0.0 16.0 8.9 19.3 39.0 72.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 31.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G2E ENSG00000188784 "Phospholipase A2 group IIE" Q9NZK7 1 19920009-19923617 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "lymphoid tissue: 7.7;skin 1: 3.2" "Cell line enhanced" "Detected in some" "CACO-2: 2.2;CAPAN-2: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064085 Uncertain "Secreted - unknown location" "HPA064085: " "unprognostic (9.56e-2)" "unprognostic (3.71e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134809-31140607 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 13.1;skin 1: 14.1;tongue: 17.4" "Group enriched" "Detected in some" 5 "AF22: 13.9;AN3-CA: 14.0;NTERA-2: 7.1;SCLC-21H: 10.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021016 Uncertain "Secreted to blood" "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favourable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" 0.1 0.0 0.1 0.1 0.2 0.0 2.0 0.4 0.9 5.3 0.1 0.1 1.9 0.5 0.3 0.1 13.1 0.0 0.1 0.1 0.6 0.0 0.3 0.1 4.2 0.1 0.1 0.4 0.1 0.1 1.7 0.1 0.1 3.1 0.4 0.0 0.8 1.8 0.5 0.3 14.1 0.1 0.1 0.1 0.1 0.9 0.3 0.1 0.4 0.8 17.4 3.5 0.1 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 14.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.9 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.9 0.6 0.0 0.1 0.4 3.1 0.1 PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828953-186988981 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 52.6;parathyroid gland: 63.5;seminal vesicle: 56.1" "Cell line enhanced" "Detected in many" "A549: 16.7;HeLa: 24.3;RPMI-8226: 30.2;U-2197: 28.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 7.1;eosinophil: 7.7;intermediate monocyte: 8.4;myeloid DC: 7.8;non-classical monocyte: 3.9;plasmacytoid DC: 3.2" "Group enriched" "Detected in many" 7 "dendritic cells: 7.8;granulocytes: 7.7;monocytes: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Cytosol 78000 Cytosol "CAB010050: AB_631312, HPA050062: , HPA054206: " "prognostic favourable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favourable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" 6.0 8.6 3.4 3.5 5.3 2.2 3.8 1.5 4.7 8.5 10.9 2.9 52.6 5.4 7.7 7.4 7.0 12.3 4.2 6.6 3.3 2.5 6.7 1.1 4.9 5.2 6.5 1.4 5.1 3.8 63.5 2.7 2.9 5.6 10.9 4.2 2.9 5.8 56.1 0.6 6.1 10.3 14.6 7.5 4.2 5.1 2.7 5.3 0.4 2.7 5.9 2.3 19.4 9.4 0.0 7.8 7.7 8.4 1.1 0.2 1.5 0.0 16.7 0.0 0.0 10.5 4.2 0.0 0.6 6.4 0.8 1.4 0.1 6.6 0.0 0.0 0.0 1.2 10.4 3.1 0.3 5.1 0.2 3.1 24.3 0.0 6.5 4.5 1.6 2.3 2.2 8.4 1.7 7.0 6.8 2.5 0.0 0.0 0.0 0.0 0.9 2.2 0.0 0.0 30.2 0.0 2.3 0.1 0.0 2.5 0.8 2.9 0.3 6.2 1.4 6.2 0.8 28.5 1.3 1.0 0.0 0.0 2.3 13.6 8.8 0.1 7.1 7.7 0.0 8.4 0.2 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.6 1.1 3.9 3.2 0.0 1.5 3.4 5.3 1.5 4.7 3.3 2.5 6.5 1.4 5.6 5.3 PLA2G4C cPLA2-gamma ENSG00000105499 "Phospholipase A2 group IVC" Q9UP65 19 48047843-48110817 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.8;skeletal muscle: 45.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 8.0;HHSteC: 13.1;TIME: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 7.9" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA043083 Approved Approved Cytosol Cytosol "HPA043083: AB_10795714" "unprognostic (1.27e-1)" "unprognostic (3.88e-2)" "unprognostic (4.18e-2)" "unprognostic (2.82e-2)" "unprognostic (7.37e-2)" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (6.53e-2)" "unprognostic (8.30e-2)" "unprognostic (1.94e-1)" "unprognostic (5.11e-3)" "unprognostic (1.90e-1)" "unprognostic (4.66e-2)" "unprognostic (9.45e-2)" "unprognostic (2.28e-3)" "unprognostic (1.87e-1)" "unprognostic (9.01e-2)" 4.0 11.7 8.9 4.2 23.2 0.4 3.0 12.9 14.5 3.4 3.5 23.4 2.0 5.1 6.8 5.2 3.6 4.3 4.6 18.5 10.0 10.0 4.4 3.8 5.9 7.2 31.8 8.5 2.0 4.1 14.8 4.6 4.1 16.9 5.7 2.9 5.4 3.1 6.7 45.0 4.9 6.7 8.1 18.6 8.1 2.4 2.4 17.1 0.7 3.3 7.5 4.3 4.9 2.1 5.4 2.0 0.0 7.9 1.5 0.8 2.0 0.6 1.1 0.0 0.3 5.1 3.0 0.1 1.3 8.0 1.2 3.4 0.0 2.1 0.0 1.7 3.2 0.2 0.0 0.2 1.9 0.8 0.1 0.0 0.3 1.1 13.1 0.0 1.7 0.6 0.3 0.5 5.3 5.0 0.0 7.2 1.9 2.0 0.0 0.1 0.1 0.1 0.1 1.8 0.6 2.4 0.3 0.7 0.1 1.4 2.5 6.2 0.7 1.8 18.3 2.2 0.7 2.5 0.9 0.4 1.3 0.2 1.6 0.0 4.3 0.0 3.2 0.0 0.2 7.9 0.6 5.4 0.8 0.0 2.0 1.6 0.0 0.0 0.0 1.5 2.0 1.4 0.2 2.0 8.9 23.2 12.9 14.5 10.0 10.0 31.8 8.5 16.9 17.1 PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981582-42051190 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 19.9" "Group enriched" "Detected in some" 7 "CACO-2: 3.4;HaCaT: 2.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041105 Enhanced "HPA041105: " "unprognostic (2.98e-1)" "unprognostic (5.52e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.22e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-7)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (4.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G4F PLA2G4F/Z ENSG00000168907 "Phospholipase A2 group IVF" Q68DD2 15 42139034-42156636 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 30.4;skin 1: 48.1" "Cell line enriched" "Detected in some" 4 "RT4: 13.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042713, HPA056752" Enhanced Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA042713: AB_10793982, HPA056752: " "unprognostic (1.99e-1)" "unprognostic (6.21e-3)" "unprognostic (1.59e-1)" "prognostic unfavourable (2.00e-4)" "unprognostic (1.06e-2)" "unprognostic (2.32e-3)" "unprognostic (1.48e-2)" "unprognostic (5.85e-2)" "unprognostic (2.25e-1)" "unprognostic (4.79e-2)" "unprognostic (6.65e-2)" "unprognostic (1.21e-2)" "unprognostic (9.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" "unprognostic (1.63e-1)" 0.1 0.1 0.0 2.5 0.3 0.3 1.8 0.0 0.1 4.5 11.0 0.0 4.7 4.2 0.4 9.7 10.4 0.2 3.1 1.0 0.0 0.0 10.8 0.2 30.4 0.1 0.0 0.0 0.1 0.1 0.7 4.1 0.3 0.0 3.3 2.5 0.0 5.3 2.8 8.6 48.1 12.3 1.1 0.1 0.2 1.6 0.1 0.0 6.2 1.6 14.9 3.4 2.2 6.3 0.6 0.3 0.2 0.1 0.0 0.3 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.7 0.5 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.0 3.2 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 13.2 0.7 0.1 0.0 1.4 0.0 1.4 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G5 ENSG00000127472 "Phospholipase A2 group V" P39877 1 20028179-20091190 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 48.3;retina: 58.3" "Cell line enhanced" "Detected in some" "EFO-21: 2.4;HaCaT: 1.0;hTEC/SVTERT24-B: 1.5;U-138 MG: 3.1;U-2197: 6.6" "Group enriched" "Detected in many" 5 "glioma: 13.0;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 23 "plasmacytoid DC: 2.3" "Lineage enriched" "Detected in single" 23 "dendritic cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053361 Approved "Secreted - unknown location" "HPA053361: " "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (5.68e-3)" "unprognostic (6.16e-2)" "unprognostic (2.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.70e-3)" "unprognostic (6.00e-5)" "unprognostic (2.87e-2)" "unprognostic (3.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.97e-3)" 2.6 0.5 2.8 2.0 6.7 0.2 1.9 1.9 5.2 0.3 10.5 2.1 2.5 1.2 0.5 2.1 5.7 1.9 3.0 48.3 2.6 2.4 0.2 1.8 3.2 1.0 6.1 2.0 17.3 1.2 0.2 0.1 8.3 6.8 6.9 3.2 58.3 1.0 10.3 0.4 0.4 1.0 19.3 1.0 0.8 2.3 3.3 1.3 0.0 0.7 0.0 1.7 7.3 2.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 3.1 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 2.8 6.7 1.9 5.2 2.6 2.4 6.1 2.0 6.8 1.3 PLA2G6 "iPLA2, iPLA2beta, NBIA2, PARK14, PNPLA9" ENSG00000184381 "Phospholipase A2 group VI" O60733 22 38111495-38205690 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" "Calmodulin-binding, Hydrolase" "Disease mutation, Dystonia, FDA approved drug targets, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 31.4;HMC-1: 20.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001171 Approved Approved "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "HPA001171: AB_1079145" "unprognostic (5.26e-2)" "prognostic favourable (7.29e-4)" "unprognostic (8.74e-2)" "unprognostic (6.27e-2)" "unprognostic (3.83e-1)" "unprognostic (3.70e-3)" "unprognostic (8.67e-3)" "unprognostic (9.55e-2)" "unprognostic (3.48e-1)" "unprognostic (1.91e-1)" "unprognostic (2.37e-3)" "unprognostic (4.95e-2)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (3.00e-1)" "unprognostic (1.48e-1)" "prognostic favourable (1.55e-4)" 16.2 17.7 15.6 8.5 20.5 13.1 15.6 15.9 26.3 14.8 7.9 36.9 18.5 9.8 16.3 20.5 8.7 21.6 25.3 6.3 19.7 7.2 18.1 8.6 9.0 12.4 19.3 16.7 21.3 12.8 24.2 12.7 6.8 19.5 17.6 6.3 12.9 20.2 17.4 7.4 18.1 8.7 7.8 14.9 12.1 9.5 30.0 23.2 16.3 45.7 4.1 11.3 12.1 11.2 1.8 5.4 4.1 0.9 8.8 5.7 1.9 0.7 2.8 3.0 7.7 10.0 4.9 8.1 0.9 0.9 0.8 1.1 3.1 1.8 5.8 6.6 2.3 3.6 3.4 1.9 1.0 8.9 13.1 31.4 3.8 3.5 2.8 3.5 20.1 16.1 4.3 2.8 4.4 1.0 5.1 10.6 1.5 4.6 6.5 2.1 2.5 1.8 4.8 1.1 4.5 2.9 6.9 5.7 2.4 1.3 3.1 7.1 3.2 2.5 1.2 2.6 4.4 1.1 0.5 17.4 3.1 3.1 3.7 4.0 1.5 4.1 0.9 0.4 3.8 0.3 1.9 1.8 3.1 5.7 1.5 1.5 1.4 3.9 3.3 8.8 0.6 5.4 3.7 1.9 15.6 20.5 15.9 26.3 19.7 7.2 19.3 16.7 19.5 23.2 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42175233-42207724 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 132.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.8;HMC-1: 55.1;LHCN-M2: 55.6;U-2197: 58.0;WM-115: 115.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 2.1;T-reg: 2.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;T-cells: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" 9900000 12000 "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favourable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavourable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 19.3 14.9 5.2 12.9 6.8 0.4 13.3 2.2 6.2 24.5 17.1 9.1 19.0 11.2 35.5 28.1 18.1 19.1 18.5 7.3 6.0 5.9 67.6 2.8 15.9 1.9 8.2 3.6 18.4 5.8 132.2 5.1 15.5 9.4 27.4 12.2 39.4 6.1 12.7 5.8 2.0 31.7 23.0 7.0 1.0 14.6 12.2 3.8 0.6 11.2 14.7 7.4 47.9 13.7 0.3 0.1 1.6 0.0 0.0 2.3 0.3 0.5 0.2 4.2 1.0 7.7 10.5 0.1 18.0 32.0 7.7 6.6 0.2 85.8 0.0 0.6 2.3 1.4 0.0 4.0 15.9 7.8 1.4 0.1 0.1 0.1 37.9 0.0 55.1 10.5 0.0 18.8 0.7 14.4 0.5 0.1 55.6 0.0 0.0 0.0 5.6 7.6 0.0 15.6 0.0 2.5 0.0 0.0 0.9 0.0 0.1 24.5 0.1 0.0 27.5 1.5 5.7 58.0 1.8 0.0 0.1 0.0 1.2 0.0 115.3 1.6 0.0 0.0 0.3 0.0 1.0 0.3 2.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.3 0.3 5.2 6.8 2.2 6.2 6.0 5.9 8.2 3.6 9.4 3.8 PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917497 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 48.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 68.9;LHCN-M2: 66.5;RPTEC TERT1: 252.9;U-251 MG: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 2.4;neutrophil: 4.5;plasmacytoid DC: 4.5" "Group enriched" "Detected in many" 11 "dendritic cells: 4.5;granulocytes: 4.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008719 Approved "Secreted to blood" 647333 58000 "HPA008719: AB_1858635" "unprognostic (1.96e-2)" "unprognostic (2.99e-2)" "unprognostic (7.40e-2)" "prognostic favourable (3.38e-4)" "unprognostic (4.73e-2)" "prognostic unfavourable (2.70e-4)" "unprognostic (1.39e-2)" "prognostic unfavourable (4.04e-4)" "unprognostic (2.26e-1)" "unprognostic (6.58e-2)" "prognostic unfavourable (1.32e-4)" "unprognostic (1.61e-1)" "prognostic unfavourable (3.51e-4)" "unprognostic (2.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" 26.7 2.4 1.0 15.5 2.1 11.3 9.7 1.6 1.5 6.9 5.8 2.9 4.9 3.8 10.7 21.2 9.1 6.5 10.7 14.3 1.3 1.0 23.3 2.3 23.4 5.5 1.6 1.5 6.8 3.7 3.6 1.8 48.4 3.1 7.5 6.7 4.5 10.6 5.0 12.2 9.0 8.1 8.4 2.5 23.8 7.8 5.8 1.3 4.8 10.9 11.6 8.2 16.3 9.3 0.1 4.5 4.5 0.4 0.0 0.0 0.3 13.0 7.0 3.0 0.1 0.2 5.0 0.1 7.9 37.2 3.2 5.1 0.1 68.9 0.0 14.7 1.1 9.0 0.0 13.3 3.7 0.7 0.0 0.0 0.3 0.1 6.1 1.1 2.6 13.3 1.6 22.2 8.6 9.2 0.0 0.0 66.5 0.0 0.0 1.7 0.8 18.3 0.0 9.0 0.0 252.9 10.3 0.0 0.0 0.0 0.3 0.2 0.0 1.8 23.3 0.2 1.6 1.7 67.9 0.0 0.1 0.1 17.9 1.9 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 4.5 0.0 0.0 4.5 0.0 0.3 1.0 2.1 1.6 1.5 1.3 1.0 1.6 1.5 3.1 1.3 PLCB1 "KIAA0581, PLC-I, PLC154" ENSG00000182621 "Phospholipase C beta 1" Q9NQ66 20 8077251-8968360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 56.7" "Cell line enhanced" "Detected in many" "CACO-2: 21.6;Hep G2: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004275, CAB005334, HPA034743, HPA057910" Enhanced Approved "Plasma membrane" 5400 "Plasma membrane" "CAB004275: AB_628118, CAB005334: AB_632196, HPA034743: , HPA057910: " "unprognostic (2.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.63e-2)" "unprognostic (9.77e-2)" "unprognostic (9.87e-2)" "unprognostic (2.37e-1)" "unprognostic (1.27e-4)" "unprognostic (1.13e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" "unprognostic (7.12e-3)" "unprognostic (6.57e-2)" "unprognostic (2.87e-3)" "unprognostic (3.20e-2)" "unprognostic (4.41e-2)" "unprognostic (1.71e-2)" "unprognostic (2.12e-1)" 5.6 7.0 13.8 4.4 27.7 3.4 5.9 7.5 31.1 6.5 9.9 2.1 20.6 5.5 8.0 10.3 4.5 7.4 6.6 8.6 15.7 9.1 10.0 3.1 4.0 1.6 9.3 14.5 3.2 10.8 56.7 4.6 14.2 5.5 10.4 3.6 1.3 19.7 22.2 9.8 2.3 4.5 12.3 4.0 2.9 5.5 2.6 8.0 4.1 3.1 1.9 1.1 8.6 6.3 0.5 0.8 2.8 3.3 2.4 5.2 0.4 0.0 0.6 2.3 0.1 4.3 8.1 3.1 9.7 6.4 2.5 1.5 21.6 2.4 1.0 4.1 1.8 0.0 1.7 0.0 1.9 0.0 2.1 0.4 1.6 32.5 1.1 0.5 0.3 0.5 0.4 3.4 0.0 5.1 3.3 12.6 0.0 2.9 0.4 1.5 7.3 3.5 6.9 0.0 5.7 1.9 8.0 8.3 3.6 0.0 2.0 0.4 9.6 3.1 0.9 8.3 3.7 0.6 6.0 9.5 11.0 16.3 4.2 5.9 14.3 0.8 3.3 2.8 3.6 0.7 5.2 0.2 1.0 1.3 0.4 0.5 0.5 1.1 2.1 2.4 0.4 0.8 0.2 0.4 13.8 27.7 7.5 30.8 15.7 9.1 9.3 14.5 5.5 8.0 PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 30.5;lymphoid tissue: 36.3" "Cell line enhanced" "Detected in some" "HEL: 30.8;HMC-1: 38.5;THP-1: 11.1;U-937: 21.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009443, HPA041298" Approved Approved Cytosol Cytosol "CAB009443: AB_632197, HPA041298: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favourable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavourable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" 6.3 3.6 8.1 17.6 11.6 30.5 2.9 1.1 7.5 2.9 3.3 16.2 1.7 4.0 2.8 3.2 2.4 4.6 6.5 3.3 6.9 5.1 3.3 4.2 12.5 17.2 12.7 2.4 1.6 2.0 1.3 2.9 4.6 9.3 3.2 5.5 4.1 5.2 2.9 1.3 1.5 10.2 4.8 17.9 36.3 3.6 1.4 10.9 12.2 2.8 1.8 17.6 6.9 2.5 1.0 4.5 8.5 4.3 1.8 3.1 2.0 0.1 0.0 0.2 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 7.7 0.6 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.8 0.0 0.0 0.0 6.5 38.5 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 1.8 3.5 0.4 0.1 5.4 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 11.1 4.0 0.0 3.7 0.0 0.0 0.0 0.0 1.4 0.0 21.1 0.0 2.7 4.2 8.5 3.1 4.3 2.0 0.7 1.6 1.6 4.5 1.0 1.6 1.8 6.9 1.8 4.2 1.6 2.9 2.0 8.1 11.6 1.1 7.5 6.9 5.1 12.7 2.4 9.3 10.9 PLCB3 ENSG00000149782 "Phospholipase C beta 3" Q01970 11 64251523-64269150 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "intestine: 77.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 4.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009257, HPA039279, HPA043907" Enhanced Enhanced Nucleoplasm 94000 Nucleoplasm "CAB009257: AB_654079, HPA039279: AB_2676425, HPA043907: AB_2678726" "unprognostic (1.30e-1)" "unprognostic (1.21e-2)" "unprognostic (2.86e-1)" "unprognostic (2.35e-1)" "unprognostic (9.35e-2)" "unprognostic (6.23e-3)" "prognostic unfavourable (1.39e-4)" "unprognostic (2.44e-2)" "unprognostic (6.61e-2)" "unprognostic (1.26e-1)" "unprognostic (8.07e-3)" "unprognostic (1.00e-2)" "prognostic unfavourable (4.31e-5)" "unprognostic (5.04e-3)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (3.88e-2)" 5.8 9.7 6.1 7.0 5.4 3.7 10.9 6.3 5.8 8.6 40.6 3.1 8.8 59.3 9.1 5.9 16.8 7.7 11.8 4.8 5.4 2.6 5.5 3.2 9.1 4.8 3.5 2.2 11.0 4.0 7.6 2.9 11.1 4.8 6.4 7.0 5.0 6.5 6.3 3.8 10.7 77.5 7.0 4.5 7.2 8.0 4.6 5.4 4.2 5.0 8.2 9.3 6.3 8.8 0.3 4.4 0.9 1.4 0.3 0.8 0.4 17.6 9.9 9.8 14.6 10.3 8.0 9.8 14.1 10.7 12.1 7.4 8.7 13.5 1.2 8.5 17.7 30.5 11.0 13.2 4.2 8.5 6.1 13.8 20.5 6.5 7.1 3.3 9.1 6.7 8.8 13.1 9.8 17.6 6.8 1.5 15.3 21.3 4.2 7.0 15.9 10.9 9.2 22.1 5.2 7.4 18.7 2.6 10.8 20.9 26.3 10.0 13.8 6.4 30.5 11.2 13.4 25.6 9.1 1.9 0.9 1.4 18.5 7.9 10.3 0.0 1.4 0.2 0.7 1.4 0.8 0.1 0.8 0.7 1.3 0.3 0.4 0.4 0.9 0.3 1.4 4.4 0.2 0.4 6.1 5.4 6.3 5.8 5.4 2.6 3.5 2.2 4.8 5.4 PLCB4 ENSG00000101333 "Phospholipase C beta 4" Q15147 20 9068763-9481242 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.9;retina: 40.2;salivary gland: 39.8" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 38.0;hTERT-HME1: 18.6;LHCN-M2: 30.6;RPTEC TERT1: 39.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.5" "Group enriched" "Detected in all" 4 "cerebellum: 44.9;pons and medulla: 11.9" "Cell type enriched" "Detected in single" 20 "plasmacytoid DC: 6.6" "Lineage enriched" "Detected in single" 20 "dendritic cells: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007951 Approved Approved Nucleoplasm,Microtubules Microtubules Nucleoplasm "HPA007951: " "unprognostic (3.88e-2)" "unprognostic (3.62e-1)" "unprognostic (1.19e-2)" "prognostic favourable (2.11e-4)" "unprognostic (1.44e-2)" "unprognostic (9.72e-3)" "unprognostic (3.32e-3)" "unprognostic (2.57e-2)" "unprognostic (7.75e-2)" "unprognostic (4.23e-2)" "unprognostic (5.21e-3)" "unprognostic (1.35e-1)" "unprognostic (4.64e-3)" "unprognostic (7.12e-2)" "unprognostic (1.37e-1)" "unprognostic (2.22e-1)" "unprognostic (4.45e-2)" 5.5 5.0 2.1 4.5 4.6 0.2 5.6 44.9 5.2 6.0 13.1 2.7 2.4 1.6 12.3 16.2 6.9 10.9 6.2 12.4 2.3 6.6 2.3 0.9 4.4 1.0 4.0 3.3 2.9 1.3 0.5 15.1 4.4 11.9 6.9 12.6 40.2 39.8 7.1 2.5 4.3 3.1 12.3 3.1 1.1 9.7 2.1 2.4 4.3 21.9 4.4 2.0 7.1 8.8 0.0 6.6 0.0 0.0 0.3 0.0 0.0 0.0 6.1 3.0 0.0 0.0 0.1 0.0 13.3 3.8 4.0 2.5 1.1 0.9 0.0 0.2 38.0 0.0 0.9 2.9 6.0 0.0 1.8 1.6 2.2 0.0 0.5 0.0 0.0 0.9 1.2 5.1 18.6 0.0 1.5 0.1 30.6 1.9 0.0 0.0 3.2 3.8 0.0 0.0 0.2 39.1 2.8 10.2 7.0 0.0 9.2 5.6 7.8 0.0 0.1 4.3 0.3 0.4 5.2 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.0 0.0 2.1 4.6 44.9 5.2 2.3 6.6 4.0 3.3 11.9 2.4 PLCD1 ENSG00000187091 "Phospholipase C delta 1" P51178 3 38007496-38029762 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 15.7;ASC TERT1: 14.0;fHDF/TERT166: 15.4;hTCEpi: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009913, HPA020107, HPA021677" Approved Approved Microtubules Microtubules "CAB009913: AB_2163388, HPA020107: AB_1855318, HPA021677: AB_1855319" "unprognostic (1.75e-3)" "unprognostic (1.01e-2)" "unprognostic (4.29e-2)" "unprognostic (1.45e-2)" "unprognostic (3.44e-1)" "unprognostic (9.67e-3)" "unprognostic (1.55e-1)" "unprognostic (7.25e-3)" "unprognostic (3.95e-1)" "unprognostic (1.45e-1)" "unprognostic (2.80e-1)" "unprognostic (2.24e-1)" "prognostic favourable (9.25e-11)" "unprognostic (1.50e-1)" "unprognostic (7.71e-2)" "unprognostic (2.93e-1)" "unprognostic (7.88e-2)" 10.9 11.3 11.2 5.6 12.1 5.1 8.0 6.0 11.2 11.6 19.3 15.2 7.3 6.6 9.1 7.6 21.9 8.6 8.5 8.0 13.0 6.9 7.8 5.8 9.4 9.3 10.5 11.4 12.8 6.2 4.7 7.3 6.9 15.9 10.6 12.7 8.3 10.9 12.6 4.5 17.0 6.5 12.3 15.5 6.3 6.5 37.3 8.7 7.7 6.6 21.2 12.2 14.6 23.1 1.0 2.6 8.6 2.4 3.7 13.2 5.4 0.6 1.7 5.6 1.5 15.7 14.0 1.7 1.7 6.7 2.6 4.0 0.6 1.3 0.4 0.9 15.4 9.0 2.9 1.7 0.8 2.5 0.7 0.2 0.9 2.8 9.2 0.0 1.0 11.3 19.2 7.8 1.0 4.9 9.4 0.8 5.7 0.7 1.3 0.6 1.5 1.7 0.5 0.8 2.1 3.1 3.0 0.0 1.6 0.5 7.5 1.8 1.6 0.7 2.8 1.6 4.0 4.1 0.0 3.4 1.3 0.3 4.0 0.0 0.8 8.6 1.9 0.1 10.2 2.4 11.6 1.0 13.2 9.8 2.6 0.5 7.8 6.1 6.9 3.7 1.4 1.5 11.8 5.4 11.2 12.1 6.0 10.7 13.0 6.9 10.5 11.4 15.9 8.7 PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108967-45133354 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 63.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Approved "Plasma membrane" "Plasma membrane" "HPA025711: AB_1855320, HPA053665: " "unprognostic (3.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" "unprognostic (4.14e-3)" "unprognostic (8.13e-3)" "prognostic unfavourable (2.89e-6)" "unprognostic (2.96e-1)" "unprognostic (9.53e-2)" "unprognostic (1.34e-3)" "unprognostic (6.21e-2)" "unprognostic (3.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "prognostic favourable (4.28e-4)" "unprognostic (3.34e-3)" 5.7 12.0 10.1 4.8 16.5 2.4 6.6 12.2 12.9 5.0 24.9 14.0 2.8 2.9 6.3 6.4 8.9 5.8 9.4 13.1 11.6 6.6 3.6 1.2 4.5 1.7 13.9 11.4 9.9 2.7 1.5 3.0 5.7 19.5 5.8 13.7 10.3 4.7 5.7 63.6 9.9 2.8 12.9 15.0 2.0 17.9 5.4 14.6 0.0 2.3 20.1 2.8 17.5 10.5 1.3 0.9 2.9 1.5 1.3 0.9 0.5 9.0 22.8 1.7 3.3 2.5 5.4 11.5 5.0 11.2 4.6 4.4 5.6 16.7 0.3 18.1 11.7 20.9 2.6 21.5 1.8 4.5 8.6 0.3 24.0 7.1 12.9 0.5 1.3 5.8 8.7 4.3 5.7 2.8 1.9 0.7 4.9 14.3 1.4 2.1 2.0 22.5 3.2 3.8 0.6 14.7 18.2 0.4 3.0 5.4 9.1 4.9 19.3 1.0 5.7 2.9 16.0 3.8 5.8 0.8 1.0 0.7 4.7 0.6 2.3 2.3 1.5 2.4 0.9 1.5 0.6 1.0 0.7 0.6 0.5 1.3 0.9 0.8 2.9 1.3 0.3 0.9 0.6 0.5 10.1 16.5 12.2 11.5 11.6 6.6 13.9 11.4 19.5 14.6 PLCD4 ENSG00000115556 "Phospholipase C delta 4" Q9BRC7 2 218607765-218637184 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "retina: 23.0;skeletal muscle: 62.5;smooth muscle: 33.1" "Cell line enhanced" "Detected in many" "SH-SY5Y: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009914, HPA038139, HPA038140" Enhanced Approved "Nuclear membrane,Plasma membrane,Cytosol" Cytosol "Nuclear membrane, Plasma membrane" "CAB009914: AB_2252306, HPA038139: AB_2675855, HPA038140: AB_2675856" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.76e-2)" "unprognostic (5.65e-5)" "unprognostic (7.77e-2)" "unprognostic (1.45e-2)" "unprognostic (7.06e-3)" "unprognostic (2.86e-2)" "unprognostic (3.15e-1)" "unprognostic (8.87e-3)" "unprognostic (7.54e-5)" "unprognostic (3.28e-2)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (6.32e-2)" "unprognostic (8.46e-3)" "unprognostic (3.09e-1)" 1.1 2.5 1.5 1.0 1.6 0.5 1.0 0.9 2.4 0.6 6.4 0.3 3.8 0.9 0.8 1.1 3.7 0.6 0.9 0.9 1.0 1.5 3.9 0.5 0.7 0.7 1.6 1.0 0.7 0.4 1.4 4.7 0.6 2.6 6.4 1.5 23.0 1.4 0.6 62.5 0.8 1.4 33.1 1.1 0.5 3.5 3.9 0.5 0.0 1.4 6.8 0.5 9.6 5.3 0.9 1.2 0.3 0.4 0.9 0.9 1.0 0.6 1.5 2.1 0.4 0.2 1.4 1.2 1.2 2.6 0.4 1.4 2.4 0.3 1.4 1.8 0.4 1.0 0.0 1.5 0.3 0.5 1.8 1.2 3.5 1.9 0.2 1.2 0.6 3.0 0.1 1.9 0.5 2.7 1.0 1.1 2.2 1.8 0.4 1.2 0.7 3.4 0.9 0.8 0.5 4.3 3.0 2.3 21.1 1.0 0.8 0.3 2.5 0.5 6.0 1.5 1.2 0.7 0.7 0.5 0.8 0.9 4.6 0.3 1.6 0.0 0.4 0.0 0.5 0.0 0.1 0.0 0.3 0.9 0.3 0.9 0.7 0.8 0.3 0.9 0.0 1.2 0.7 1.0 1.5 1.6 0.9 2.4 1.0 1.5 1.6 1.0 2.6 0.5 PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 94030812-94332823 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 44.6" "Cell line enhanced" "Detected in many" "RT4: 18.7;U-2 OS: 11.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol Cytosol "HPA015597: AB_1855321, HPA015598: AB_1855322" "unprognostic (4.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.59e-3)" "unprognostic (3.01e-1)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (4.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-3)" "unprognostic (3.56e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" "unprognostic (4.30e-2)" 3.2 2.4 4.1 9.1 5.5 0.0 2.2 1.8 7.9 9.2 13.8 3.1 1.6 5.0 11.4 4.6 4.5 4.2 3.8 12.8 4.1 2.6 6.3 0.7 7.2 0.4 2.4 6.8 3.2 12.8 0.1 5.2 3.1 6.4 3.3 12.6 44.6 2.1 7.7 4.3 0.7 4.6 5.8 2.4 5.8 8.7 1.7 2.3 0.0 15.1 7.3 1.1 7.9 5.4 3.2 1.2 0.8 0.9 1.1 2.3 0.5 6.0 8.3 1.8 1.0 1.0 5.9 2.3 3.7 1.0 0.8 1.2 5.4 1.5 0.7 1.9 3.0 2.6 4.2 1.0 1.3 0.4 2.1 0.4 4.6 0.5 0.1 0.8 0.3 2.4 0.0 2.2 0.0 0.0 0.4 0.3 7.2 0.2 0.7 0.8 0.6 8.7 0.1 5.7 0.2 0.2 18.7 0.8 1.5 4.4 6.0 0.5 5.1 0.5 0.6 3.9 11.2 2.3 4.9 0.5 0.2 0.3 3.1 1.0 3.5 0.4 0.5 0.1 1.5 0.9 1.3 2.6 1.6 1.1 0.6 3.2 2.3 1.8 0.8 1.1 0.8 1.2 0.6 0.5 4.1 5.5 1.8 7.9 4.1 2.6 2.4 6.8 6.4 2.3 PLCG1 "NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1" ENSG00000124181 "Phospholipase C gamma 1" P19174 20 41136960-41196801 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 5.9;MAIT T-cell: 8.0;memory CD4 T-cell: 5.2;memory CD8 T-cell: 4.9;naive CD4 T-cell: 5.7;naive CD8 T-cell: 5.4;NK-cell: 4.0;T-reg: 4.4" "Group enriched" "Detected in many" 8 "NK-cells: 4.0;T-cells: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004277, HPA036681, HPA036682" Approved Enhanced Cytosol Cytosol "CAB004277: AB_628119, HPA036681: , HPA036682: " "unprognostic (2.77e-1)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "unprognostic (4.31e-2)" "unprognostic (5.82e-2)" "unprognostic (2.09e-2)" "unprognostic (4.45e-3)" "unprognostic (1.25e-2)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "prognostic favourable (4.72e-4)" "unprognostic (3.32e-1)" "unprognostic (2.73e-3)" "unprognostic (1.82e-1)" "unprognostic (2.65e-1)" "unprognostic (9.27e-2)" "unprognostic (2.79e-2)" 20.2 15.1 25.1 20.9 22.1 8.3 34.9 52.6 26.8 19.9 13.9 23.4 12.5 16.5 27.6 13.9 13.5 17.0 18.7 20.9 25.4 13.6 15.3 6.8 19.3 30.7 18.5 20.5 28.7 9.1 16.9 14.2 22.2 18.7 18.4 13.2 20.0 13.2 20.6 13.4 22.3 17.1 22.2 15.4 20.1 12.4 19.9 23.9 48.1 28.5 11.9 21.9 17.1 21.1 0.7 0.0 0.0 0.0 4.0 8.0 3.3 5.3 6.8 32.9 24.1 13.2 9.3 10.5 8.8 11.4 17.8 15.2 16.4 1.8 12.0 10.9 9.6 10.0 14.3 15.8 10.4 3.4 7.6 0.8 11.4 19.3 10.0 4.7 3.3 11.8 8.9 13.1 10.3 19.9 8.9 7.9 16.1 40.1 28.9 3.7 12.2 12.6 23.1 24.0 5.9 9.8 9.9 11.7 22.4 15.8 7.4 15.9 8.6 5.5 21.4 42.7 13.9 13.6 10.7 8.9 3.9 10.0 10.2 5.1 17.7 0.0 0.0 0.0 5.9 0.0 8.0 0.3 5.2 4.9 0.0 0.7 5.7 5.4 0.0 4.0 0.0 0.0 4.4 3.3 25.1 22.1 52.6 26.8 25.4 13.6 18.5 20.5 18.7 23.9 PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81739097-81962693 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 55.8" "Cell line enhanced" "Detected in some" "Daudi: 39.6;HMC-1: 19.0;U-698: 87.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Vesicles 21000 Vesicles "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favourable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favourable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" 8.4 3.8 3.3 55.8 4.9 14.1 10.7 1.0 2.4 5.6 10.3 5.3 3.1 8.7 11.2 12.2 6.0 4.7 10.1 4.4 3.3 2.8 20.6 8.8 10.7 35.5 5.2 1.8 2.0 3.6 1.0 1.8 4.1 4.5 4.3 3.6 4.6 8.8 2.8 2.0 4.1 17.6 4.6 8.6 33.6 4.2 2.3 4.2 6.3 5.3 2.6 44.6 7.5 7.7 18.8 3.9 26.8 12.2 14.0 1.1 2.3 0.3 0.7 0.1 0.6 0.0 0.0 0.9 0.0 0.0 0.5 0.2 0.2 1.7 39.6 6.8 0.0 0.9 0.8 0.1 0.3 0.3 0.4 4.7 0.0 0.0 0.2 4.7 19.0 0.0 0.4 0.3 0.2 0.9 0.5 3.3 0.0 1.2 0.5 11.9 0.7 0.2 16.1 0.0 5.0 0.1 0.8 0.3 0.0 1.1 0.3 0.3 0.7 14.6 0.2 0.0 0.7 0.1 0.1 7.9 12.9 87.9 0.0 6.5 0.3 2.8 4.4 26.8 0.7 5.7 0.3 18.8 0.2 1.1 3.9 17.3 0.3 0.8 24.8 14.0 12.2 2.6 0.1 2.3 3.3 4.9 1.0 2.4 3.3 2.8 5.2 1.8 4.5 4.2 PLCH1 "DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3" ENSG00000114805 "Phospholipase C eta 1" Q4KWH8 3 155375580-155745067 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.7;testis: 15.8" "Cell line enhanced" "Detected in some" "A549: 8.2;AF22: 26.6;NTERA-2: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.2" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036176, HPA057978" Uncertain Enhanced Vesicles Vesicles "HPA036176: AB_10671837, HPA057978: " "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (2.17e-2)" "unprognostic (1.55e-2)" "unprognostic (3.50e-4)" "unprognostic (6.41e-2)" "unprognostic (2.94e-5)" "unprognostic (5.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.24e-3)" "unprognostic (4.84e-2)" "unprognostic (1.76e-2)" "prognostic favourable (3.03e-5)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-2)" 0.3 0.3 3.9 0.7 14.1 0.5 3.9 7.4 14.7 2.1 3.9 5.7 4.1 3.9 1.4 12.9 0.5 12.4 2.4 2.5 4.5 3.6 2.1 0.4 6.1 0.3 3.4 7.3 0.5 2.5 0.8 3.2 0.8 6.5 0.8 3.9 5.6 2.3 3.4 0.6 0.5 3.9 0.5 1.9 0.3 5.8 15.8 2.9 0.0 8.9 0.0 0.4 1.3 0.4 0.1 0.3 0.7 0.0 0.0 1.2 0.9 0.0 8.2 26.6 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.5 6.6 0.0 0.5 0.0 0.0 4.7 0.0 0.0 0.0 2.4 6.6 0.0 0.9 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.8 1.5 6.1 14.1 1.1 0.6 0.0 0.0 1.6 0.1 2.5 0.6 0.0 6.4 0.0 2.8 0.0 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.9 3.9 14.1 7.4 14.7 4.5 3.6 3.4 7.3 6.5 2.9 PLCH2 "KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1" ENSG00000149527 "Phospholipase C eta 2" O75038 1 2425980-2505530 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0;retina: 28.6;skin 1: 36.6" "Group enriched" "Detected in some" 4 "HBEC3-KT: 49.5;hTCEpi: 23.3;hTERT-HME1: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 9 "NK-cells: 2.9;T-cells: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072705 Enhanced "HPA072705: " "unprognostic (2.06e-3)" "unprognostic (1.30e-2)" "unprognostic (1.09e-3)" "unprognostic (3.84e-3)" "unprognostic (1.99e-1)" "unprognostic (1.59e-2)" "unprognostic (7.39e-2)" "unprognostic (7.70e-2)" "unprognostic (7.58e-2)" "unprognostic (9.28e-2)" "unprognostic (2.26e-1)" "unprognostic (5.95e-2)" "unprognostic (6.61e-3)" "unprognostic (8.43e-2)" "unprognostic (1.07e-1)" "unprognostic (8.64e-2)" "unprognostic (5.80e-2)" 0.5 1.2 6.4 2.9 9.1 1.4 3.1 32.0 25.1 3.2 0.9 1.6 0.5 1.6 0.3 1.7 9.7 2.5 2.4 0.3 20.2 2.7 0.8 0.8 1.2 4.0 2.6 8.4 0.2 1.7 0.1 3.0 0.4 2.6 6.7 0.7 28.6 8.6 4.9 0.2 36.6 2.0 0.2 6.4 4.0 1.7 0.8 2.0 0.2 1.2 0.2 4.9 8.3 6.4 0.3 0.1 0.0 0.0 2.9 2.4 0.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 6.9 0.0 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 13.9 0.0 0.0 1.2 0.1 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 2.7 5.6 1.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.9 0.3 1.5 1.4 0.0 0.3 1.1 0.7 0.0 2.9 0.0 0.1 2.1 0.9 6.4 9.1 32.0 25.1 20.2 2.7 2.6 8.4 2.6 2.0 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600405-171810950 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 52.1" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 29.9;SK-MEL-30: 16.7;TIME: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 10.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004527, HPA042396" Enhanced "CAB004527: AB_677324, HPA042396: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (4.76e-6)" 7.0 26.6 5.3 6.1 20.4 4.5 6.3 1.4 10.8 8.6 19.7 31.4 1.8 27.7 6.9 4.9 25.0 4.9 52.1 14.7 7.7 4.7 7.5 20.2 4.4 5.2 25.3 7.2 17.1 13.9 0.9 2.7 6.6 18.8 3.5 9.4 8.5 13.2 4.2 2.0 17.6 29.5 3.4 16.8 9.9 5.3 3.5 21.8 0.9 4.1 10.7 8.5 4.3 11.5 0.1 0.9 10.2 2.6 3.0 4.1 0.8 2.3 3.7 1.9 0.7 5.9 6.7 4.1 1.2 5.2 1.8 2.3 0.5 3.3 0.0 9.3 0.5 7.8 0.3 1.0 3.0 1.9 1.6 2.2 5.9 13.0 2.7 3.8 10.4 2.6 5.7 2.2 1.0 29.9 1.4 0.0 0.4 0.6 0.0 3.2 0.4 2.7 0.1 0.8 0.0 4.7 0.9 0.0 0.0 4.1 2.5 16.7 4.6 5.0 26.0 0.8 3.2 2.1 1.3 5.0 4.0 0.0 3.6 4.5 1.0 10.2 2.6 3.2 0.5 1.6 4.1 0.0 0.4 1.0 0.9 0.1 0.0 0.1 1.5 3.0 0.5 0.0 1.2 0.8 5.3 20.4 1.4 10.8 7.7 4.7 25.3 7.2 18.8 21.8 PLD2 ENSG00000129219 "Phospholipase D2" O14939 17 4807096-4823434 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013397 Approved "HPA013397: AB_1855328" "unprognostic (1.87e-1)" "unprognostic (3.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (2.90e-2)" "unprognostic (3.85e-3)" "unprognostic (3.64e-1)" "unprognostic (6.15e-3)" "unprognostic (2.58e-3)" "unprognostic (1.25e-1)" "unprognostic (8.10e-3)" "unprognostic (1.08e-1)" "unprognostic (2.95e-1)" "unprognostic (1.91e-1)" "unprognostic (1.85e-1)" "unprognostic (5.48e-2)" 9.9 6.4 9.0 8.2 10.4 2.0 11.0 14.6 10.8 14.9 7.6 18.1 13.4 6.1 11.2 11.7 36.2 13.0 12.3 7.2 10.5 7.8 7.2 6.9 11.7 7.5 10.0 7.0 14.9 12.6 11.4 6.5 14.6 12.2 11.0 8.1 9.8 13.7 26.7 4.3 27.8 6.1 11.8 8.9 7.8 7.0 3.5 13.2 7.3 7.3 20.0 16.8 10.6 20.6 2.6 5.3 4.1 7.4 1.1 3.1 2.9 7.4 11.9 10.7 11.2 9.2 12.3 12.0 4.9 10.3 8.6 6.9 12.5 8.9 3.3 5.7 12.5 17.3 8.2 10.8 8.0 4.1 4.1 1.1 8.8 7.7 6.7 0.0 8.2 18.1 16.4 7.7 7.0 19.8 1.2 3.1 6.6 5.7 0.4 1.4 5.6 5.2 3.6 6.8 0.8 7.8 12.8 3.5 6.3 9.1 10.8 6.7 7.7 1.8 15.4 5.7 5.8 12.7 7.5 2.8 1.3 0.7 8.7 1.5 3.3 4.1 6.9 1.6 2.0 7.4 1.5 2.6 2.0 1.5 5.3 1.5 0.6 0.7 0.5 1.1 7.2 2.3 3.1 2.9 9.0 10.4 14.6 10.8 10.5 7.8 10.0 7.0 12.2 13.2 PLD3 HU-K4 ENSG00000105223 "Phospholipase D family member 3" Q8IV08 19 40348456-40380439 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response" "Exonuclease, Hydrolase, Nuclease" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "basophil: 149.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 149.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012800, CAB020812" Approved Supported "Endoplasmic reticulum,Cytosol" 490000 "Endoplasmic reticulum, Cytosol" "CAB020812: , HPA012800: AB_1855330" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.64e-3)" "unprognostic (2.56e-3)" "unprognostic (2.06e-3)" "unprognostic (2.68e-1)" "unprognostic (4.52e-2)" "unprognostic (3.89e-2)" "unprognostic (1.09e-1)" "unprognostic (4.60e-2)" "prognostic favourable (6.44e-4)" "unprognostic (4.34e-2)" "prognostic favourable (2.21e-4)" "unprognostic (3.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (6.42e-2)" 45.7 57.5 44.6 23.1 79.0 12.8 21.9 35.5 126.1 31.2 23.5 25.4 17.1 22.6 26.3 35.0 18.3 30.0 30.8 33.0 46.4 73.4 22.1 25.6 49.7 25.2 44.7 53.9 44.8 42.5 32.9 122.1 38.9 62.2 29.6 16.1 31.6 35.3 37.2 27.4 24.2 23.5 25.6 28.6 48.9 23.0 17.0 19.3 11.9 20.6 11.2 12.9 27.3 20.7 3.6 23.0 149.2 24.6 9.7 7.8 16.8 13.9 43.2 28.0 44.0 77.9 37.1 21.3 34.7 35.4 25.2 28.9 8.2 15.8 6.1 36.4 30.1 6.5 6.7 13.6 11.0 22.6 24.6 6.5 14.8 10.3 53.2 2.7 75.0 70.6 28.5 19.2 13.2 21.1 23.0 24.6 18.1 18.3 4.7 13.0 18.2 8.9 6.0 21.3 24.9 12.9 10.5 20.1 33.4 16.6 10.3 18.5 14.2 47.0 37.2 21.3 10.2 18.0 7.7 25.6 27.3 6.3 34.2 10.9 13.1 149.2 24.6 35.3 7.8 12.8 6.4 3.6 6.2 6.9 23.0 3.1 6.5 6.5 2.5 9.7 5.7 3.3 6.1 16.8 44.6 79.0 35.5 126.1 46.4 73.4 44.7 53.9 62.2 19.3 PLD4 C14orf175 ENSG00000166428 "Phospholipase D family member 4" Q96BZ4 14 104924816-104937790 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "blood: 229.9" "Group enriched" "Detected in some" 5 "HMC-1: 34.0;RPMI-8226: 24.4;THP-1: 61.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "plasmacytoid DC: 229.9" "Lineage enriched" "Detected in many" 5 "dendritic cells: 229.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051512 Uncertain 2000000 "HPA051512: " "unprognostic (4.50e-3)" "unprognostic (1.78e-4)" "unprognostic (7.12e-2)" "unprognostic (5.30e-3)" "unprognostic (5.54e-2)" "unprognostic (2.91e-3)" "unprognostic (2.56e-1)" "unprognostic (4.76e-3)" "unprognostic (1.45e-3)" "unprognostic (1.19e-3)" "unprognostic (3.45e-3)" "unprognostic (3.89e-1)" "unprognostic (6.90e-3)" "unprognostic (8.94e-2)" "unprognostic (2.83e-1)" "unprognostic (1.28e-2)" "unprognostic (2.41e-1)" 0.7 1.6 8.9 6.7 8.8 15.0 1.9 5.7 10.0 1.5 1.3 23.1 0.1 5.6 1.5 0.5 1.1 2.8 3.5 0.8 8.7 8.4 1.2 0.9 2.6 14.4 14.5 3.4 0.9 1.6 1.0 2.8 1.2 9.0 2.1 0.8 1.5 4.6 2.3 0.5 0.9 5.5 0.9 19.0 11.6 3.5 0.8 9.2 2.7 1.0 0.0 11.2 3.9 0.9 14.7 229.9 43.4 17.7 1.7 0.1 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.0 8.6 0.0 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.9 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 2.8 43.4 0.0 11.9 0.1 14.7 0.0 0.0 35.1 12.3 0.1 0.0 0.6 1.7 17.7 229.9 0.0 4.4 8.9 8.8 5.7 9.6 8.7 8.4 14.5 3.4 9.0 9.2 PLG ENSG00000122194 Plasminogen P00747 6 160702238-160753315 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 269.9" "Cell line enhanced" "Detected in some" "HL-60: 3.5;RH-30: 3.9;U-698: 2.0;U-937: 1.6" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000668, CAB016678, HPA021602, HPA048823" Supported "Secreted to blood" 140000000000 41000000000 "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: " "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favourable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 269.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.3 0.2 0.8 0.0 0.4 3.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 1.0 0.0 2.0 0.0 1.6 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 83.9;testis: 32.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "T-reg: 9.0" "Lineage enriched" "Detected in many" 5 "T-cells: 9.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA051638, HPA053229" Approved "HPA051638: , HPA053229: " "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavourable (2.70e-7)" "prognostic unfavourable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavourable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 2.9 1.1 1.1 14.2 1.5 15.9 1.7 2.1 1.1 1.5 7.1 0.7 0.5 6.0 1.1 0.9 10.4 0.7 1.5 1.0 1.0 0.8 1.3 1.2 2.6 15.2 0.8 0.6 1.2 0.7 0.0 0.8 6.8 0.7 0.9 5.9 0.5 1.7 0.8 0.8 2.9 5.9 2.0 0.7 8.3 3.6 32.4 0.5 83.9 0.6 6.6 20.4 2.1 2.6 1.9 0.5 0.7 0.1 1.3 9.0 2.3 43.1 45.0 37.2 20.2 1.1 2.6 20.9 24.7 16.3 38.7 28.9 39.3 28.5 21.6 12.9 16.6 24.8 50.7 20.3 46.6 30.7 28.6 27.4 35.5 53.7 0.3 31.6 30.1 1.0 1.1 27.4 28.3 28.3 42.6 29.8 29.8 39.4 29.7 31.6 42.5 22.9 46.5 25.3 34.3 11.0 9.4 21.0 14.6 28.2 19.8 12.8 25.2 19.5 14.3 18.4 23.6 18.0 42.1 21.2 33.0 37.4 15.6 27.5 30.1 0.0 0.1 0.0 0.0 0.0 0.0 1.9 1.4 0.5 0.5 0.0 0.0 0.0 0.7 1.3 0.0 0.0 9.0 2.3 1.1 1.5 2.1 1.1 1.0 0.8 0.8 0.6 0.7 0.5 PLK2 SNK ENSG00000145632 "Polo like kinase 2" Q9NYY3 5 58453982-58460260 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 42.9;T-47d: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 10.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009624, HPA069329" Approved Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "CAB009624: AB_2167745, HPA069329: " "unprognostic (4.82e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-1)" "unprognostic (6.51e-2)" "prognostic unfavourable (7.75e-4)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (2.44e-2)" "unprognostic (1.06e-2)" "unprognostic (1.01e-1)" "unprognostic (3.11e-1)" "prognostic unfavourable (2.08e-4)" "unprognostic (6.56e-2)" "unprognostic (1.43e-1)" "unprognostic (3.46e-1)" "unprognostic (1.95e-3)" 11.4 3.7 19.6 4.0 40.2 4.4 23.4 1.3 39.4 20.6 5.7 3.7 5.0 5.1 19.2 7.1 17.7 9.5 18.2 28.1 18.8 5.1 6.9 17.6 17.7 3.8 4.2 20.6 11.8 12.6 3.8 3.3 25.9 8.7 8.7 8.7 12.6 22.1 6.2 8.7 20.9 6.1 15.4 2.7 54.7 4.7 19.8 7.4 1.0 8.9 16.6 7.5 14.2 15.5 1.2 2.9 3.0 1.6 10.4 1.2 0.6 22.9 20.7 7.2 0.5 3.8 6.2 2.8 4.9 8.2 16.3 9.5 1.5 20.3 0.0 32.3 17.6 28.8 0.3 11.3 14.9 0.0 0.6 0.0 9.3 1.7 20.7 0.1 0.6 3.6 15.7 6.3 17.6 32.8 0.0 0.8 32.2 8.3 0.0 0.0 1.3 3.4 1.1 20.0 0.0 42.9 4.6 0.4 0.9 15.1 3.0 13.2 72.3 0.3 41.8 4.5 12.2 2.0 39.1 0.0 0.0 0.0 3.5 0.0 20.0 3.0 0.7 2.3 0.1 1.6 0.0 1.2 0.7 0.0 2.9 0.9 1.2 0.6 1.9 10.4 0.6 2.0 0.5 0.6 19.6 40.2 1.3 39.4 18.8 5.1 4.2 20.6 8.7 7.4 PLK3 "CNK, FNK, PRK" ENSG00000173846 "Polo like kinase 3" Q9H4B4 1 44800225-44805990 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060318 Enhanced "HPA060318: " "unprognostic (1.06e-1)" "unprognostic (8.71e-2)" "unprognostic (3.69e-2)" "unprognostic (3.51e-3)" "unprognostic (3.09e-2)" "unprognostic (4.72e-2)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (5.12e-3)" "unprognostic (6.78e-2)" "unprognostic (7.67e-3)" "unprognostic (2.79e-2)" "prognostic unfavourable (1.75e-4)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" 14.8 7.6 4.4 16.3 18.8 8.6 10.0 2.4 6.4 8.6 5.3 13.9 3.2 4.0 9.9 5.8 23.9 8.5 21.6 6.8 10.5 6.0 6.7 9.0 14.9 10.0 9.9 2.5 7.8 10.7 15.6 9.0 29.6 14.8 6.4 4.0 7.6 8.2 6.8 7.0 16.6 7.0 6.0 15.2 9.1 6.1 4.5 5.6 4.6 8.4 25.0 18.2 9.9 9.5 1.3 4.2 2.8 5.1 0.6 11.0 3.5 4.1 2.7 4.2 1.9 3.1 10.2 7.8 9.8 13.8 3.7 3.8 1.6 5.9 5.1 4.1 8.0 3.8 2.3 13.4 2.1 8.2 0.7 5.6 1.5 3.6 15.3 1.8 7.2 7.9 8.0 11.1 10.9 11.7 2.9 2.1 8.4 2.7 3.7 1.6 2.8 3.3 4.4 2.8 7.3 13.3 1.6 3.2 2.0 2.6 4.6 10.8 0.4 1.8 14.9 2.3 5.7 4.5 5.7 5.9 2.7 1.3 4.9 2.9 4.5 0.0 2.9 0.8 1.7 5.0 2.1 1.3 9.9 4.2 4.2 1.1 11.0 4.9 2.8 0.6 5.1 1.8 10.5 3.5 4.4 18.8 2.4 6.4 10.5 6.0 9.9 2.5 14.8 5.6 PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880861-127899195 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.5;lymphoid tissue: 21.7;testis: 21.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol "Centrosome, Cytosol" "HPA017327: , HPA035026: AB_10602080, HPA043198: " "unprognostic (2.44e-1)" "unprognostic (4.24e-2)" "prognostic favourable (7.46e-5)" "unprognostic (2.18e-1)" "unprognostic (3.79e-1)" "unprognostic (9.20e-2)" "unprognostic (1.06e-5)" "prognostic unfavourable (5.13e-4)" "unprognostic (1.44e-3)" "unprognostic (5.66e-2)" "prognostic unfavourable (5.14e-4)" "unprognostic (1.27e-1)" "unprognostic (2.22e-11)" "unprognostic (2.29e-2)" "unprognostic (3.58e-1)" "unprognostic (4.75e-2)" "unprognostic (7.93e-2)" 1.4 1.3 1.5 4.7 2.4 16.5 2.2 0.5 2.2 2.0 3.2 0.3 0.6 2.3 1.3 1.3 5.4 1.1 1.2 2.0 1.2 1.3 1.5 0.9 1.5 5.9 1.2 1.4 1.5 0.9 0.3 0.6 5.0 2.6 1.4 3.7 0.8 1.7 0.7 0.4 2.7 3.2 1.9 1.8 2.7 1.6 21.7 1.0 21.7 1.0 2.1 6.0 1.5 2.2 0.7 0.7 1.5 0.8 1.4 4.0 0.8 11.6 5.5 20.7 10.6 0.7 2.0 9.4 11.4 8.1 15.2 15.8 7.7 12.0 15.7 4.2 6.3 7.7 14.6 9.1 23.5 12.2 6.0 14.2 8.8 7.2 0.2 20.0 16.9 0.6 0.9 13.9 6.4 11.7 16.5 21.0 12.8 8.1 30.8 9.0 9.6 6.3 16.1 14.5 5.4 5.0 7.4 11.5 9.4 7.2 6.6 3.5 5.3 8.7 5.0 12.0 11.6 8.1 14.2 10.9 11.9 22.4 6.1 15.3 13.2 0.0 0.4 1.5 1.6 0.8 1.1 0.3 1.8 1.7 0.7 0.7 0.6 2.3 0.0 1.4 0.3 0.4 4.0 0.8 1.5 2.4 0.5 2.2 1.2 1.3 1.2 1.4 2.6 1.0 PLK5 "PLK5P, SgK384ps" ENSG00000185988 "Polo like kinase 5" Q496M5 19 1524074-1536046 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 50.1" "Cell line enhanced" "Detected in some" "Daudi: 5.0" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in all" 6 "cerebellum: 50.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA035024 Enhanced "HPA035024: " "unprognostic (4.32e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-1)" "unprognostic (7.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-1)" "unprognostic (2.69e-1)" "unprognostic (8.38e-2)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" "unprognostic (3.36e-2)" "unprognostic (9.94e-3)" "unprognostic (2.18e-3)" "unprognostic (3.21e-1)" "unprognostic (7.49e-2)" "unprognostic (3.54e-2)" "unprognostic (4.01e-4)" 0.4 0.7 8.3 0.4 4.8 1.7 0.8 50.1 7.9 5.9 0.4 1.6 0.3 0.5 6.4 6.2 1.6 2.7 0.4 0.3 3.2 1.7 0.3 0.3 0.3 0.4 1.1 1.9 0.8 0.6 0.5 0.5 0.3 2.9 0.9 0.4 8.4 0.6 3.2 0.5 1.0 0.7 2.8 0.8 0.4 0.2 7.4 1.8 0.0 0.4 0.0 0.3 0.2 2.9 1.2 1.2 4.4 0.9 1.0 1.1 0.1 0.2 0.9 0.8 1.2 0.4 0.9 1.0 0.2 0.5 0.5 0.4 0.5 1.0 5.0 0.3 0.5 1.2 0.8 0.5 0.2 0.5 0.6 1.0 1.3 0.8 0.1 0.2 1.1 1.0 0.3 0.8 0.2 0.3 0.8 1.7 0.8 1.0 0.4 1.0 1.4 0.9 1.0 0.3 0.4 0.6 0.1 0.5 0.7 0.7 0.4 0.3 1.5 0.7 0.0 0.9 1.0 1.2 0.2 1.5 0.4 0.6 0.4 0.7 0.5 1.6 0.9 2.2 0.8 0.5 0.5 0.7 0.8 0.5 0.2 1.2 1.1 0.6 4.4 1.0 0.6 1.2 1.0 0.1 8.3 4.8 50.1 7.9 3.2 1.7 1.1 1.9 2.9 1.8 PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease mutation, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" 2700000 Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavourable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavourable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavourable (2.43e-4)" 29.0 19.5 14.9 16.8 24.0 7.1 32.1 12.1 17.6 35.8 21.7 17.0 17.7 19.1 34.2 21.1 16.5 24.7 21.3 31.2 17.6 14.8 27.5 51.3 22.2 19.7 24.5 9.9 31.8 30.3 18.2 16.3 41.5 20.8 21.1 12.0 25.1 39.3 22.0 18.3 13.3 20.8 39.0 13.2 21.1 18.6 10.0 22.4 1.7 34.8 11.1 8.2 19.5 69.7 1.6 16.3 17.7 19.4 2.6 9.1 9.3 17.6 15.1 8.3 38.9 56.9 31.9 6.7 52.5 69.7 27.7 47.1 17.2 11.6 10.2 55.5 57.9 14.9 12.1 18.3 19.1 10.6 12.9 5.5 24.3 21.8 35.3 3.4 26.8 38.7 9.6 33.4 13.4 49.0 15.4 5.0 28.8 11.4 0.8 9.2 3.7 22.5 4.1 16.9 22.1 15.9 4.0 3.2 13.2 22.9 15.7 26.4 7.9 8.8 48.4 31.7 23.8 39.6 25.7 11.7 19.1 6.1 70.2 12.1 51.6 0.0 19.4 0.9 9.1 17.2 1.6 1.0 1.6 4.4 16.3 1.6 0.6 3.4 17.7 2.6 15.0 2.4 1.0 9.3 14.9 24.0 12.1 17.6 17.6 14.8 24.5 9.9 20.8 22.4 PLOD2 LH2 ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146069440-146163653 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 73.1" "Cell line enhanced" "Detected in many" "HBF TERT88: 85.3;U-87 MG: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavourable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavourable (7.64e-10)" "prognostic unfavourable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavourable (4.99e-11)" "prognostic unfavourable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" 36.7 14.1 11.2 18.0 12.1 0.7 28.5 7.9 13.5 8.8 25.2 5.1 8.3 21.6 14.8 7.5 12.0 8.0 22.3 16.6 12.5 8.2 16.4 73.1 9.3 3.0 10.7 4.8 17.7 14.4 13.9 7.8 41.0 13.0 11.1 16.1 7.2 7.7 11.3 4.8 3.2 24.7 24.2 19.4 3.2 13.6 6.3 10.9 6.1 47.6 3.5 3.0 21.8 28.7 0.0 0.0 1.5 0.3 0.0 0.0 1.9 17.0 12.2 3.8 1.2 13.9 15.0 9.7 60.4 18.5 32.9 62.1 0.9 1.7 0.0 11.8 10.2 3.6 4.4 51.9 85.3 0.0 7.0 4.2 11.9 8.4 35.8 0.0 0.0 26.2 7.5 28.5 13.9 45.4 5.6 0.2 58.1 6.2 0.0 0.0 2.4 5.2 0.0 2.5 0.0 13.8 0.8 1.9 0.0 48.1 5.2 5.1 14.1 0.5 57.0 40.8 12.4 12.9 36.0 18.5 2.6 0.0 76.0 0.0 7.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.9 11.2 12.1 7.9 13.5 12.5 8.2 10.7 4.8 13.0 10.9 PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 103.6;WM-115: 99.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 13.4;monocytes: 14.3;T-cells: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001236 Uncertain "Secreted - unknown location" 370000 "HPA001236: AB_1855474" "unprognostic (1.15e-1)" "prognostic unfavourable (1.91e-5)" "prognostic unfavourable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" 23.9 16.1 11.9 19.5 24.0 14.6 35.4 7.2 19.2 17.8 20.0 31.2 16.6 22.7 22.9 15.1 11.0 17.4 16.7 22.1 14.8 11.6 20.2 54.1 21.0 18.2 36.3 8.9 16.1 23.2 18.5 16.5 33.1 22.4 14.4 14.2 11.1 11.3 19.6 8.8 14.0 23.2 23.2 29.0 20.4 16.7 10.1 30.6 5.1 16.8 6.0 6.9 17.3 42.6 2.6 13.4 2.8 14.3 2.5 9.2 5.3 9.9 9.0 3.8 25.2 18.1 13.0 7.7 18.3 20.6 18.8 13.6 14.4 12.9 0.8 20.6 31.6 12.1 7.6 10.7 4.8 5.4 3.4 1.0 10.9 14.1 24.9 4.5 8.5 14.0 10.3 11.0 8.7 16.7 9.6 103.6 12.6 28.4 0.4 10.7 8.0 13.7 3.1 5.1 15.4 6.4 2.9 2.9 17.1 11.4 16.7 40.8 3.1 15.5 14.5 28.5 13.9 34.5 22.5 5.8 10.6 0.6 16.9 10.9 99.9 0.0 10.8 2.8 9.2 14.3 8.1 2.6 6.8 6.1 10.4 1.8 3.2 3.4 1.0 2.5 14.3 13.4 4.3 5.3 11.9 24.0 7.2 19.2 14.8 11.6 36.3 8.9 22.4 30.6 PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55535050 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 91.2;fHDF/TERT166: 27.7;HMC-1: 47.8;HSkMC: 35.0" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" "Plasma membrane" "CAB033331: AB_2168044, HPA047815: " "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favourable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavourable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" 56.3 26.7 12.5 14.8 14.6 0.6 57.9 10.6 18.5 34.5 30.9 26.1 18.0 17.3 36.8 26.0 18.4 20.4 61.0 33.7 13.4 10.8 34.5 42.0 15.9 17.3 20.8 10.1 16.5 17.6 16.9 10.1 22.4 21.4 82.0 24.7 29.8 9.8 24.0 18.4 16.6 25.4 39.6 28.2 10.2 21.7 18.1 14.5 4.4 32.7 9.6 10.0 43.1 18.1 5.4 13.6 3.3 0.7 2.7 9.5 1.6 1.9 4.8 1.4 2.8 91.2 10.6 2.0 4.3 12.1 2.4 5.6 3.3 3.6 2.0 4.1 27.7 1.2 4.9 2.4 2.7 1.3 3.9 0.2 2.1 4.1 14.4 0.5 47.8 35.0 5.1 3.5 2.2 3.9 0.0 5.5 4.7 1.2 1.3 1.0 3.2 3.9 0.4 2.4 0.1 9.1 15.5 1.7 1.2 4.3 0.8 2.6 3.1 0.3 4.8 0.8 1.4 3.6 3.1 3.4 1.4 2.3 3.2 0.2 3.9 0.0 0.4 3.3 1.5 0.4 1.6 5.4 5.2 3.2 1.9 3.4 9.5 7.5 0.3 2.7 0.7 13.6 2.2 1.6 12.5 14.6 10.6 18.5 13.4 10.8 20.8 10.1 21.4 14.5 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291504 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 38.3;CAPAN-2: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 4.4;MAIT T-cell: 9.4" "Lineage enriched" "Detected in single" 52 "T-cells: 9.4" "Low region specificity" "Detected in many" HPA055540 Uncertain Approved Mitochondria Mitochondria "HPA055540: " "prognostic unfavourable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favourable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 1.4 4.7 8.3 5.3 20.9 0.2 17.5 2.0 11.1 30.4 18.2 28.1 13.4 27.5 7.7 4.1 9.1 38.1 31.2 1.5 13.6 7.1 4.7 1.1 3.7 0.8 37.1 6.5 2.4 19.8 0.6 4.1 1.8 16.6 10.7 15.3 6.7 45.8 19.0 0.3 19.0 21.9 3.3 26.0 1.4 22.2 2.2 25.8 0.7 2.2 5.9 5.0 12.1 5.7 0.0 0.1 0.1 0.0 0.0 9.4 0.3 22.5 38.3 0.5 0.0 0.0 0.1 0.0 2.2 0.0 7.1 5.5 11.0 41.6 0.0 24.5 3.3 12.5 0.0 4.9 3.2 0.2 0.7 0.0 15.4 0.0 8.5 0.0 1.5 1.5 2.1 3.6 4.9 1.2 0.1 0.0 0.0 25.6 0.1 0.0 17.0 0.0 0.0 0.0 0.6 17.9 3.6 4.8 11.5 6.3 10.5 16.5 13.8 0.7 1.2 15.6 10.3 0.1 16.6 0.2 26.2 18.5 4.4 0.0 12.8 0.0 0.0 0.0 4.4 0.0 9.4 0.0 2.0 2.2 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 8.3 20.9 2.0 11.1 13.6 7.1 37.1 6.5 16.6 25.8 PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494747-56645301 "Enzymes, Plasma proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 102.8;ASC TERT1: 51.4;HSkMC: 63.5;U-2197: 93.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 5.4;naive B-cell: 4.5" "Lineage enriched" "Detected in single" 7 "B-cells: 5.4" "HPA028892, HPA072751" Uncertain Supported "Golgi apparatus" "Golgi apparatus" "HPA028892: AB_10602149, HPA072751: " "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favourable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" 46.4 17.2 29.0 10.8 30.7 4.2 39.1 13.5 27.5 102.7 15.5 33.8 22.1 8.1 32.7 36.9 20.8 36.7 24.0 23.3 39.9 13.5 30.2 57.7 24.3 6.7 19.2 30.1 27.9 12.2 30.7 7.2 70.9 20.0 37.7 14.4 34.7 22.4 58.7 16.6 24.4 12.5 32.9 16.5 7.9 18.7 23.4 29.7 5.2 107.1 19.4 6.7 35.8 44.0 5.4 0.0 0.8 0.3 0.0 0.0 0.2 0.4 1.5 2.0 0.2 102.8 51.4 4.9 5.4 5.5 5.0 2.5 4.3 0.8 0.7 0.6 8.1 0.8 0.2 0.1 1.0 0.0 1.3 0.1 0.6 6.0 2.5 0.0 0.0 63.5 0.4 4.8 4.0 4.7 0.3 0.0 5.4 0.4 0.0 0.0 6.1 5.9 0.0 0.0 0.2 0.8 4.5 0.0 4.0 1.7 2.2 0.5 0.7 0.0 2.9 25.2 2.1 93.3 0.2 0.0 0.0 0.0 4.4 0.2 1.7 0.0 0.3 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 4.5 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.2 29.0 30.7 13.5 27.5 39.9 13.5 19.2 30.1 20.0 29.7 PLPP4 "DPPL2, PPAPDC1, PPAPDC1A" ENSG00000203805 "Phospholipid phosphatase 4" Q5VZY2 10 120456954-120589855 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.5;kidney: 12.6" "Cell line enhanced" "Detected in some" "BJ: 15.1;fHDF/TERT166: 10.7;TIME: 12.0;U-138 MG: 9.6;U-251 MG: 46.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 22 "eosinophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045188 Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA045188: " "unprognostic (8.19e-2)" "unprognostic (2.94e-2)" "unprognostic (8.86e-2)" "unprognostic (1.90e-3)" "unprognostic (3.45e-1)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (2.26e-3)" "unprognostic (1.55e-1)" "unprognostic (8.62e-3)" "unprognostic (2.70e-3)" "unprognostic (1.89e-1)" "unprognostic (2.40e-3)" "unprognostic (3.49e-2)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-3)" 0.6 1.7 11.4 1.2 13.6 4.9 3.1 11.6 18.2 3.4 1.2 12.1 1.0 0.7 1.7 2.7 0.9 1.2 11.3 0.7 15.9 17.4 12.6 2.8 0.5 0.6 15.5 6.0 0.6 0.6 0.4 0.5 0.6 26.5 3.0 0.8 0.0 2.0 6.1 0.4 1.7 0.8 1.5 19.1 0.5 1.2 11.1 12.5 0.0 1.5 0.0 0.5 0.8 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 1.1 2.3 1.4 0.1 1.3 0.0 0.0 10.7 0.1 0.9 0.2 1.2 1.4 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 1.1 0.0 8.7 0.9 2.1 0.9 0.0 0.0 0.0 0.9 2.7 0.0 0.0 0.0 4.4 0.0 0.8 0.2 0.7 0.0 0.7 1.9 0.0 12.0 9.6 5.3 0.5 46.4 0.0 0.0 0.0 8.9 0.0 2.5 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 13.6 11.6 10.0 15.9 17.4 15.5 6.0 26.5 12.5 PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Predicted membrane proteins" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 77.8" "Cell line enhanced" "Detected in many" "RPMI-8226: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "memory B-cell: 37.2;naive B-cell: 65.4" "Lineage enriched" "Detected in all" 5 "B-cells: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055777 Approved Vesicles Vesicles "HPA055777: " "unprognostic (4.54e-2)" "unprognostic (2.51e-3)" "unprognostic (3.66e-2)" "prognostic favourable (1.48e-5)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (5.58e-2)" "prognostic favourable (8.72e-5)" "unprognostic (9.79e-2)" "prognostic favourable (2.42e-5)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "prognostic unfavourable (8.33e-10)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (1.57e-2)" 5.5 9.3 6.9 11.9 7.9 4.8 8.8 7.5 6.7 11.2 11.5 3.9 33.9 14.4 5.7 30.9 6.6 10.2 21.0 4.6 6.1 6.1 9.6 20.3 7.5 12.0 4.5 5.1 8.4 77.8 4.2 29.9 8.3 6.7 27.9 12.8 16.2 52.0 36.5 2.3 4.7 18.4 5.2 3.5 12.8 16.1 4.6 4.4 3.8 11.9 5.0 14.8 8.0 6.7 65.4 5.3 13.3 3.6 4.3 5.0 3.7 5.4 10.9 6.5 13.3 12.8 12.5 9.0 15.6 19.7 8.0 10.5 5.0 8.4 0.4 13.3 16.1 6.1 5.4 11.4 6.9 3.4 3.5 9.6 4.6 14.6 21.8 2.8 11.7 9.8 11.9 11.1 14.6 12.9 0.4 25.2 9.7 11.3 6.3 4.7 9.9 3.7 6.9 4.8 50.8 20.0 7.1 5.2 7.9 6.4 9.9 9.1 21.3 5.4 7.7 5.7 5.0 9.5 4.1 15.7 10.2 1.6 15.6 7.4 9.7 13.3 2.7 4.5 3.0 2.7 5.0 37.2 3.9 3.8 2.5 65.4 2.0 1.9 1.6 4.3 3.6 5.3 3.4 3.7 6.9 7.9 7.5 6.7 6.1 6.1 4.5 5.1 6.7 4.4 PLPPR2 "LPPR2, PRG-4" ENSG00000105520 "Phospholipid phosphatase related 2" Q96GM1 19 11355386-11365698 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "neutrophil: 32.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048973 Uncertain Approved Nucleoplasm Nucleoplasm "HPA048973: " "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "prognostic unfavourable (6.45e-4)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (7.10e-2)" "unprognostic (1.37e-1)" "unprognostic (9.60e-2)" "unprognostic (1.72e-1)" "prognostic favourable (6.82e-4)" "unprognostic (2.23e-1)" "prognostic unfavourable (7.46e-11)" "unprognostic (1.99e-2)" "unprognostic (1.46e-1)" "unprognostic (4.37e-2)" "unprognostic (1.17e-1)" 12.0 17.1 32.5 10.5 39.9 14.1 6.6 17.7 51.2 14.0 11.1 10.8 5.1 6.0 12.7 8.4 8.4 9.7 13.7 10.4 37.0 22.3 5.5 18.0 10.0 5.4 11.8 17.9 15.2 12.4 11.7 22.7 11.5 12.3 18.5 5.1 11.8 13.1 15.1 23.1 16.2 5.7 16.8 10.5 10.6 9.3 7.6 9.4 0.5 7.7 4.4 3.3 9.8 8.1 0.0 2.9 32.3 7.2 0.0 0.3 2.3 8.7 5.4 3.0 12.5 12.7 12.2 0.8 15.6 14.6 9.7 9.9 1.0 1.6 1.7 9.3 19.9 1.6 1.7 4.7 5.2 4.6 3.2 0.5 3.8 1.0 6.6 0.5 17.8 10.9 8.5 8.3 1.6 6.5 8.4 14.0 8.1 12.9 0.2 2.4 3.3 30.4 0.2 0.4 4.8 4.5 4.1 3.2 10.8 6.5 5.6 3.3 8.1 11.2 7.5 22.0 4.7 37.1 8.2 8.7 5.3 0.6 21.3 8.0 8.6 0.8 7.2 3.7 0.3 6.7 0.0 0.0 0.1 0.0 2.9 0.0 0.1 0.0 32.3 0.0 4.4 0.1 0.3 2.3 32.5 39.9 17.7 51.2 37.0 22.3 11.8 17.9 12.3 9.4 PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821977 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 18.2;brain: 30.0;fallopian tube: 12.6" "Group enriched" "Detected in some" 6 "NB-4: 23.5;THP-1: 49.8" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 8 "eosinophil: 1.6" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: , HPA057034: " "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.33e-2)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.32e-1)" "unprognostic (4.51e-4)" "unprognostic (8.06e-3)" "unprognostic (1.07e-1)" "unprognostic (1.72e-12)" "unprognostic (1.21e-2)" "unprognostic (6.82e-2)" "unprognostic (8.50e-2)" "unprognostic (2.91e-1)" 0.7 0.7 20.5 1.2 30.0 18.2 2.1 0.1 21.3 0.9 0.7 0.7 0.0 0.7 1.3 0.7 0.7 12.6 1.1 0.7 14.4 13.1 0.7 0.7 2.6 0.9 3.9 14.9 1.0 0.7 0.7 0.1 0.8 4.7 0.9 0.7 0.1 0.7 0.8 0.9 0.8 1.0 0.7 1.1 0.9 0.9 3.0 3.1 0.0 0.7 0.0 0.7 0.8 0.0 0.1 0.0 1.6 0.0 0.0 0.1 0.0 0.1 0.6 4.8 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.4 0.0 0.1 0.9 0.0 0.0 0.0 2.0 0.0 0.6 0.0 0.2 1.6 0.1 0.6 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.4 0.0 23.5 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 6.2 0.1 0.0 0.0 2.1 49.8 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 3.8 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 30.0 0.1 21.3 14.4 13.1 3.9 14.9 4.7 3.1 PM20D2 "ACY1L2, bA63L7.3" ENSG00000146281 "Peptidase M20 domain containing 2" Q8IYS1 6 89146050-89165565 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 34.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030325, HPA030326, HPA030327" Approved Enhanced Nucleoplasm Nucleoplasm "HPA030325: , HPA030326: , HPA030327: AB_10603129" "unprognostic (3.60e-2)" "unprognostic (1.40e-1)" "unprognostic (6.36e-2)" "unprognostic (3.18e-3)" "unprognostic (3.22e-2)" "unprognostic (2.73e-1)" "unprognostic (1.13e-3)" "unprognostic (8.60e-2)" "unprognostic (1.04e-1)" "unprognostic (5.86e-2)" "unprognostic (2.27e-2)" "unprognostic (1.04e-1)" "unprognostic (9.99e-2)" "unprognostic (6.84e-2)" "unprognostic (1.28e-1)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" 6.8 5.0 4.8 11.4 6.9 6.5 7.6 11.2 4.9 11.9 13.4 4.4 9.3 7.0 11.3 7.1 14.2 11.0 9.1 16.9 5.1 5.5 9.6 9.7 6.2 8.3 3.7 3.1 21.0 11.3 12.5 23.8 6.9 8.6 23.5 8.5 17.6 8.6 8.7 38.5 10.2 8.0 27.7 4.8 5.2 7.6 4.0 2.9 16.6 23.0 10.6 12.1 19.5 8.5 4.1 2.4 3.0 1.0 4.8 4.0 1.5 11.6 5.2 4.7 7.3 1.5 1.0 0.3 5.9 5.9 8.8 11.3 6.1 5.7 34.1 7.2 1.3 4.5 9.5 4.7 20.1 10.5 12.2 6.9 3.2 5.7 1.7 19.8 5.5 1.5 3.5 3.3 7.1 2.1 2.6 18.3 2.7 1.8 12.4 15.7 1.9 5.2 20.7 23.3 24.7 9.9 2.2 13.2 9.2 3.5 5.7 5.8 0.0 17.5 3.4 0.2 5.3 1.8 12.3 9.7 14.2 7.3 2.4 17.1 0.8 1.9 1.0 2.9 2.2 0.6 3.5 4.1 2.7 3.7 1.6 3.1 4.0 3.5 3.0 4.8 0.6 2.4 0.5 1.5 4.8 6.9 11.2 3.9 5.1 5.5 3.7 3.1 8.6 2.9 PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576894-41589890 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favourable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favourable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favourable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" 20.8 25.1 24.3 15.2 28.8 15.3 15.0 15.5 27.9 24.7 29.5 12.6 14.1 25.3 12.1 20.1 36.5 24.8 14.7 17.7 19.6 20.6 32.8 32.2 21.7 10.8 20.3 25.5 34.8 30.5 7.7 8.7 9.7 17.8 13.7 13.9 11.8 13.0 17.3 6.6 13.6 22.0 14.3 15.2 6.0 24.5 27.6 13.2 8.8 8.9 12.7 14.7 15.2 13.2 10.6 13.2 24.5 12.7 6.8 27.1 10.3 5.2 9.8 6.7 14.4 19.4 30.2 7.8 21.0 24.0 19.4 21.4 7.8 5.1 4.9 7.0 25.0 7.9 8.8 13.6 10.9 10.3 13.4 1.2 12.3 16.4 30.7 7.4 8.1 25.1 13.2 20.1 8.4 3.1 5.4 17.8 26.3 13.9 5.6 10.7 2.1 13.2 4.3 7.2 10.2 8.2 5.7 1.9 3.8 17.1 6.1 25.1 7.0 8.2 2.4 22.0 12.1 20.4 10.7 11.2 10.7 7.9 24.5 6.2 13.2 9.6 12.7 24.5 16.3 10.2 13.8 10.4 16.8 13.8 13.2 10.6 18.3 12.9 16.6 6.8 12.0 5.0 27.1 10.3 24.3 28.8 15.5 27.9 19.6 20.6 20.3 25.5 17.8 13.2 PMM2 "CDG1, CDG1a, CDGS, PMI, PMI1" ENSG00000140650 "Phosphomannomutase 2" O15305 16 8788823-8849331 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "basophil: 52.2" "Lineage enriched" "Detected in all" 10 "granulocytes: 52.2" "Low region specificity" "Detected in all" "HPA040852, HPA063649" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA040852: AB_10794069, HPA063649: AB_2685074" "unprognostic (8.62e-3)" "unprognostic (8.00e-3)" "prognostic favourable (1.04e-4)" "unprognostic (3.58e-2)" "unprognostic (1.79e-1)" "unprognostic (1.98e-2)" "unprognostic (6.09e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (5.14e-3)" "unprognostic (2.62e-1)" "prognostic unfavourable (8.97e-6)" "unprognostic (1.22e-1)" "unprognostic (2.50e-2)" "unprognostic (6.89e-2)" "unprognostic (5.02e-2)" 14.8 13.1 6.8 15.4 9.0 4.3 13.6 8.2 8.2 11.4 19.4 7.0 11.6 18.9 9.7 13.1 22.7 10.0 13.9 10.7 4.7 2.9 14.6 43.3 11.8 11.2 6.6 4.3 7.8 40.4 7.8 28.3 19.9 6.6 12.0 20.4 8.8 21.2 13.5 12.5 13.2 19.6 9.5 5.7 12.0 15.2 9.7 7.8 7.6 10.0 12.0 22.0 10.5 12.2 2.9 3.5 52.2 4.9 1.6 3.6 3.0 10.9 24.5 5.4 14.2 9.7 15.3 12.1 17.1 20.7 17.2 18.6 18.3 13.6 17.5 7.2 29.8 15.2 11.1 20.9 17.6 13.0 13.0 5.8 14.8 31.2 18.4 15.3 13.9 22.8 14.9 18.3 16.9 17.5 7.8 17.1 11.4 28.7 15.6 14.1 23.0 15.9 19.9 12.1 34.8 19.1 19.4 10.3 19.5 14.1 31.1 10.2 20.2 13.4 20.3 12.4 14.0 33.4 16.7 21.2 17.7 22.0 10.3 19.3 16.4 52.2 4.9 0.9 2.5 3.7 3.6 2.9 2.2 3.2 3.5 2.4 2.5 2.4 7.8 1.6 2.3 3.2 1.6 3.0 6.8 9.0 8.2 8.2 4.7 2.9 6.6 4.3 6.6 7.8 PMPCA "Alpha-MPP, INPP5E, KIAA0123" ENSG00000165688 "Peptidase, mitochondrial processing alpha subunit" Q10713 9 136410570-136423761 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Disease mutation, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021648, HPA063735" Supported Enhanced Mitochondria 6500 Mitochondria "HPA021648: AB_1855491, HPA063735: AB_2685108" "unprognostic (9.80e-2)" "unprognostic (1.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.69e-2)" "unprognostic (4.01e-2)" "unprognostic (8.19e-2)" "unprognostic (6.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.97e-1)" "unprognostic (3.32e-2)" "prognostic favourable (8.00e-5)" "unprognostic (9.47e-3)" "prognostic favourable (2.14e-6)" "unprognostic (4.27e-3)" "unprognostic (1.57e-2)" "unprognostic (2.40e-1)" "unprognostic (3.54e-2)" 15.2 27.3 19.8 14.6 23.8 20.1 13.2 20.3 24.3 12.3 15.1 13.0 10.4 18.6 14.2 14.1 16.5 13.6 14.9 37.0 15.6 14.8 17.0 48.3 12.3 18.4 15.2 21.9 15.5 18.2 14.7 19.5 15.6 16.8 15.2 11.9 12.8 20.3 17.1 56.7 17.5 17.0 13.8 14.1 18.9 16.3 23.2 12.5 14.0 15.0 19.8 15.3 13.1 13.4 25.5 30.1 17.0 25.1 32.1 30.8 28.2 14.3 26.9 12.9 26.0 9.8 14.3 19.8 15.0 12.1 21.0 15.3 30.7 17.2 20.1 15.8 15.2 33.6 23.8 22.0 9.3 28.9 28.8 16.2 34.7 37.1 17.3 21.0 14.1 21.0 15.2 16.3 8.4 17.7 41.0 13.3 13.0 39.8 19.8 27.1 26.3 25.5 24.7 18.3 44.5 14.4 10.3 26.5 17.4 20.2 28.8 17.5 39.2 28.7 14.6 15.0 16.1 12.3 19.0 8.2 10.9 21.7 19.7 18.4 13.4 15.4 25.1 17.0 27.2 24.4 26.4 25.5 25.7 29.3 30.1 23.7 30.8 26.9 5.9 32.1 23.2 15.3 24.3 28.2 19.8 23.8 20.3 24.3 15.6 14.8 15.2 21.9 16.8 12.5 PMPCB "MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing beta subunit" O75439 7 103297422-103329511 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria 57000 Mitochondria "HPA040674: AB_10961998, HPA074168: " "prognostic favourable (2.79e-4)" "unprognostic (3.11e-1)" "unprognostic (7.18e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-2)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "unprognostic (7.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.42e-3)" "prognostic favourable (2.95e-8)" "unprognostic (2.59e-2)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" 29.1 41.8 31.8 23.0 34.3 41.5 31.6 41.1 38.4 29.0 26.9 21.6 28.2 35.1 32.0 25.9 27.9 26.9 23.5 41.4 27.7 20.1 45.9 47.2 21.9 31.3 32.6 35.0 36.8 40.6 41.1 33.9 24.8 34.2 31.6 31.5 20.8 30.6 31.0 31.5 31.6 31.0 25.7 27.8 27.9 33.6 31.3 35.9 37.2 33.2 24.2 30.0 30.7 27.9 19.5 18.4 9.7 16.1 12.9 21.9 15.7 12.1 17.6 20.8 27.9 12.6 25.6 15.7 11.3 19.5 22.9 27.3 18.8 14.0 31.3 18.2 19.3 15.8 24.9 18.2 21.9 10.9 29.7 10.8 30.2 25.0 15.4 14.8 12.8 23.4 17.0 17.9 17.3 12.1 20.9 31.8 20.9 28.3 24.6 35.0 25.4 22.1 17.2 14.5 31.8 21.5 21.8 26.1 31.9 15.3 45.2 22.3 18.5 19.9 10.0 20.3 24.3 36.0 21.0 24.4 31.2 24.0 15.0 24.0 15.9 9.7 14.1 9.3 14.7 16.1 16.1 19.5 17.1 14.7 18.4 14.3 21.5 17.4 4.4 12.9 13.6 9.4 21.9 15.7 31.8 34.3 41.1 38.4 27.7 20.1 32.6 35.0 34.2 35.9 PMVK "HUMPMKI, PMK, PMKA" ENSG00000163344 "Phosphomevalonate kinase" Q15126 1 154924734-154936991 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029900 Approved "HPA029900: AB_10601390" "unprognostic (2.52e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.31e-1)" "unprognostic (1.81e-2)" "unprognostic (8.13e-2)" "unprognostic (5.47e-2)" "unprognostic (8.22e-2)" "prognostic favourable (9.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "prognostic favourable (4.96e-4)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" 21.0 28.3 31.3 15.9 34.0 7.2 19.4 13.9 31.7 17.0 18.9 25.3 10.2 26.4 12.1 14.7 30.1 20.2 15.7 24.7 23.9 23.9 26.9 39.3 16.2 18.7 29.6 29.3 18.8 22.2 26.8 26.1 13.8 22.4 17.0 12.0 22.2 18.8 15.9 39.8 26.1 25.2 16.7 23.9 20.5 21.8 15.9 22.8 9.9 17.8 25.3 18.9 12.2 22.8 29.1 22.9 20.4 47.3 13.4 30.4 17.7 11.6 16.4 10.6 16.6 9.8 7.0 11.3 9.4 6.4 8.6 8.3 6.6 23.1 16.6 18.1 10.6 11.4 14.3 13.9 4.0 23.2 6.6 7.6 22.2 6.2 9.1 11.5 6.9 8.3 13.0 15.6 11.1 8.7 8.0 51.4 8.9 23.2 9.0 11.1 9.6 21.1 13.7 6.9 38.1 14.5 8.5 8.9 21.3 10.1 17.6 11.5 33.7 20.4 7.3 8.4 6.9 19.9 14.0 41.8 33.3 29.2 13.9 18.5 10.8 4.6 19.8 20.4 17.5 46.9 27.9 29.1 24.0 17.8 22.1 23.9 15.7 15.7 1.7 13.4 47.3 22.9 30.4 17.7 31.3 34.0 13.9 31.7 23.9 23.9 29.6 29.3 22.4 22.8 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669730-153689010 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4;seminal vesicle: 38.5" "Cell line enriched" "Detected in some" 8 "AN3-CA: 26.5" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.8 21.4 2.2 35.4 0.6 0.9 3.7 24.9 0.9 21.9 0.9 6.9 3.8 4.2 3.1 14.5 2.9 2.9 3.8 19.5 17.0 1.0 0.5 0.7 0.6 6.1 15.5 0.7 0.5 1.4 0.3 2.4 3.8 12.6 4.2 0.4 0.7 38.5 2.2 1.4 5.2 15.3 2.6 0.7 5.5 4.7 1.7 0.0 0.5 0.0 0.7 10.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 26.5 0.0 0.0 2.8 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.4 0.0 0.0 0.0 3.2 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.1 0.0 0.1 2.1 0.2 0.3 0.0 0.2 1.1 0.0 0.2 0.2 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 35.4 3.7 23.2 19.5 17.0 6.1 15.5 3.8 1.7 PNKP PNK ENSG00000039650 "Polynucleotide kinase 3'-phosphatase" Q96T60 19 49859882-49878351 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease mutation, Epilepsy, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006782 Supported Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA006782: AB_1855496" "prognostic favourable (9.18e-4)" "unprognostic (1.87e-1)" "unprognostic (4.31e-2)" "unprognostic (4.23e-1)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.24e-1)" "unprognostic (3.36e-1)" "unprognostic (1.58e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "unprognostic (4.55e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.24e-2)" "unprognostic (3.68e-3)" 13.1 32.4 11.2 22.0 11.8 24.3 15.0 18.0 13.8 14.0 17.4 17.0 26.4 15.6 16.7 25.3 13.6 18.1 18.2 16.8 12.3 9.5 20.1 16.8 15.9 21.0 13.9 14.2 17.1 22.5 19.7 26.8 17.1 12.9 18.7 15.0 19.6 20.3 22.4 12.8 15.3 15.7 13.2 10.1 30.7 17.9 17.2 13.9 22.3 23.0 17.0 20.6 14.6 12.4 7.9 7.5 19.3 12.7 2.7 7.7 3.8 12.8 8.7 8.8 13.8 8.4 6.5 14.3 20.8 10.6 9.6 8.4 6.9 16.9 8.3 6.6 6.3 10.5 3.1 11.7 5.7 10.7 13.3 14.1 16.4 6.0 6.3 13.3 19.0 6.1 6.2 8.7 5.7 12.6 6.9 16.8 12.5 8.2 13.5 10.7 8.2 17.7 11.5 8.1 16.8 9.9 27.5 10.4 16.8 9.1 27.4 4.6 4.7 8.3 17.8 18.8 11.5 4.5 17.1 18.6 7.5 6.7 17.0 6.0 14.9 1.4 8.8 12.2 7.7 8.5 6.4 6.5 6.6 5.8 7.5 7.9 4.9 4.4 19.3 2.7 12.7 4.3 6.8 3.8 11.2 11.8 18.0 13.8 12.3 9.5 13.9 14.2 12.9 13.9 PNLDC1 "dJ195P10.2, FLJ40240" ENSG00000146453 "PARN like, ribonuclease domain containing 1" Q8NA58 6 159800249-159820704 "Enzymes, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 26.7" "Cell line enhanced" "Detected in some" "AN3-CA: 1.8;HAP1: 2.3;hTCEpi: 3.8;RPMI-8226: 2.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basal ganglia: 5.7;cerebral cortex: 3.9" "Cell type enhanced" "Detected in some" "intermediate monocyte: 1.8;plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA052026 Uncertain "HPA052026: " "unprognostic (1.58e-1)" "unprognostic (3.88e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-3)" "unprognostic (8.47e-3)" "unprognostic (3.55e-2)" "unprognostic (2.04e-1)" "unprognostic (4.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.37e-2)" "unprognostic (4.19e-1)" "unprognostic (9.98e-2)" "unprognostic (2.69e-9)" "unprognostic (1.14e-2)" "unprognostic (2.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-1)" 0.6 0.5 0.6 0.5 5.7 0.4 1.4 0.2 3.9 0.3 0.3 0.3 0.0 0.2 0.3 1.3 0.2 3.6 0.3 0.2 0.7 0.2 0.8 0.8 0.5 0.4 0.4 0.7 0.8 2.3 0.3 0.3 0.3 0.3 0.4 0.3 0.0 1.2 0.4 0.5 1.4 0.3 0.3 0.4 0.5 0.3 26.7 0.3 0.5 0.4 0.3 0.7 0.2 0.0 0.1 1.7 0.0 1.8 0.4 1.0 0.4 0.0 0.4 0.2 1.8 1.0 0.0 1.1 0.0 0.0 0.1 0.0 1.3 0.0 0.1 0.2 0.3 0.1 2.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.0 3.8 0.0 0.1 0.0 0.1 0.8 0.2 0.1 0.8 0.1 0.9 0.8 0.1 0.0 2.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.2 0.3 0.0 0.3 0.7 0.1 0.0 0.6 0.1 0.0 0.2 0.0 0.1 1.8 0.0 0.0 0.2 0.0 0.7 0.1 1.0 0.1 0.0 0.4 0.0 1.7 0.5 0.4 0.6 5.7 0.2 3.9 0.7 0.2 0.4 0.7 0.3 0.3 PNLIP PL ENSG00000175535 "Pancreatic lipase" P16233 10 116545931-116567855 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1895 "pancreas: 3207.8" "Cell line enhanced" "Detected in some" "EFO-21: 3.0;HDLM-2: 2.7;U-2 OS: 4.5;U-251 MG: 1.0;U-266/84: 1.5" "Cancer enriched" "Detected in some" 4854 "pancreatic cancer: 2731.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 0.4" "HPA062430, HPA062494" Enhanced "Secreted to digestive system" 13000000 "HPA062430: AB_2684761, HPA062494: AB_2684782" "unprognostic (2.05e-2)" "unprognostic (4.46e-2)" 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.6 3207.8 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 1.0 0.0 1.5 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PNLIPRP3 ENSG00000203837 "Pancreatic lipase related protein 3" Q17RR3 10 116427867-116477957 "Enzymes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 8.5;breast: 15.9;esophagus: 12.0;skin 1: 15.5" "Cell line enriched" "Detected in some" 18 "hTCEpi: 84.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046202, HPA052009" Uncertain "Secreted - unknown location" "HPA046202: AB_10959739, HPA052009: " "unprognostic (2.62e-4)" "unprognostic (1.60e-1)" "unprognostic (6.97e-2)" 8.5 0.1 0.0 0.0 0.2 0.0 15.9 0.0 0.0 1.6 0.2 0.0 0.0 0.1 0.0 0.4 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 15.5 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.3 0.0 8.1 1.9 0.7 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 84.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 PNMT PENT ENSG00000141744 "Phenylethanolamine N-methyltransferase" P11086 17 39667981-39670475 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 94.6;ductus deferens: 53.7;seminal vesicle: 40.7" "Cell line enhanced" "Detected in some" "HEL: 4.7;K-562: 10.2;NB-4: 20.2;NTERA-2: 3.9;SCLC-21H: 5.5;SH-SY5Y: 5.0" "Cancer enhanced" "Detected in many" "cervical cancer: 27.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "gdT-cell: 2.5" "Group enriched" "Detected in many" 5 "B-cells: 1.0;T-cells: 2.5" "Region enhanced" "Detected in some" "basal ganglia: 1.3" "Low region specificity" "Detected in single" "CAB017029, HPA043412, HPA051005" Enhanced "CAB017029: , HPA043412: AB_2630373, HPA051005: AB_2681306" "unprognostic (1.50e-1)" "unprognostic (3.74e-2)" "unprognostic (1.08e-1)" "prognostic unfavourable (3.95e-5)" "unprognostic (4.27e-2)" "unprognostic (3.02e-1)" "unprognostic (2.98e-2)" "unprognostic (5.75e-2)" "unprognostic (5.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (1.52e-4)" "unprognostic (1.58e-1)" "unprognostic (1.97e-1)" "unprognostic (4.72e-2)" "unprognostic (1.87e-2)" 2.3 94.6 3.9 0.8 13.8 1.6 5.4 0.9 3.0 1.3 1.9 1.5 53.7 0.9 1.0 2.7 0.9 1.9 0.8 4.9 1.7 5.4 1.0 0.7 1.6 0.8 9.1 1.5 0.9 0.7 2.4 12.9 2.4 3.6 4.3 0.7 0.9 0.7 40.7 10.5 0.8 1.0 0.8 0.7 0.9 0.9 1.3 2.7 0.0 0.7 0.8 0.7 1.3 1.7 1.0 0.0 0.3 0.3 0.0 2.5 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.4 4.7 0.1 0.4 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 20.2 3.9 0.0 0.1 0.0 0.3 0.0 0.0 5.5 5.0 0.0 2.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.4 1.0 0.4 1.5 0.0 0.4 0.0 0.7 0.3 0.0 0.3 0.0 0.0 0.3 3.9 13.8 0.9 3.0 1.7 5.4 9.1 1.5 3.6 2.7 PNP "NP, PUNP" ENSG00000198805 "Purine nucleoside phosphorylase" P00491 14 20468954-20477094 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 153.1" "Cell line enhanced" "Detected in many" "HL-60: 81.4;U-937: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001625 Enhanced Supported Cytosol 100000000 Cytosol "HPA001625: AB_1854577" "unprognostic (1.20e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" "unprognostic (1.70e-1)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "prognostic unfavourable (4.43e-4)" "unprognostic (4.94e-3)" "unprognostic (3.87e-2)" "unprognostic (7.45e-2)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "prognostic favourable (2.24e-4)" "unprognostic (1.69e-1)" "unprognostic (7.54e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" 24.7 7.6 9.5 15.0 14.0 69.4 15.7 13.9 11.8 9.5 19.1 6.2 25.2 29.4 5.9 153.1 34.0 7.8 15.7 12.1 11.5 8.4 49.7 24.2 18.3 13.2 13.5 3.4 3.6 11.0 8.7 8.4 45.3 17.7 6.0 16.1 3.8 9.2 7.9 3.3 10.6 32.0 9.8 16.3 18.0 17.0 4.5 12.5 7.0 7.1 21.7 19.1 7.5 14.7 13.1 20.7 4.1 12.4 15.7 33.7 12.1 13.2 17.9 3.8 8.6 4.3 3.5 11.7 13.6 6.4 11.1 11.0 10.3 12.2 35.4 15.8 7.2 14.3 20.1 25.6 14.8 11.4 17.7 29.6 15.3 17.0 4.0 81.4 15.4 2.3 9.3 33.5 14.8 47.3 14.5 22.1 13.9 12.3 23.9 48.0 10.8 29.9 20.2 5.7 13.7 39.4 12.6 16.6 3.7 26.0 33.2 2.1 12.2 14.5 37.9 7.6 10.1 17.1 23.0 10.2 17.0 40.1 6.5 92.8 0.7 4.0 12.4 4.1 18.1 11.5 33.7 11.2 20.3 20.0 20.7 13.1 12.9 16.3 1.6 15.7 10.6 11.7 6.9 12.1 9.5 14.0 13.9 11.8 11.5 8.4 13.5 3.4 17.7 12.5 PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818902-825573 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 158.1;breast: 155.2" "Cell line enhanced" "Detected in all" "ASC diff: 64.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" "Lipid droplets" Nucleoplasm "HPA055173: , HPA062602: , HPA075175: " "unprognostic (2.11e-2)" "unprognostic (3.37e-2)" "unprognostic (5.87e-3)" "unprognostic (2.51e-2)" "unprognostic (8.97e-3)" "unprognostic (1.68e-2)" "unprognostic (6.39e-2)" "unprognostic (3.28e-2)" "unprognostic (3.00e-1)" "unprognostic (5.61e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (5.46e-1)" "unprognostic (4.09e-1)" "unprognostic (2.07e-2)" 158.1 7.2 1.6 9.4 1.8 11.2 155.2 2.7 2.3 4.1 35.9 1.5 3.8 5.6 4.5 7.8 8.6 4.3 7.2 12.6 1.7 1.1 15.6 7.4 11.3 4.5 1.6 1.6 4.9 11.8 2.5 4.2 11.6 1.8 5.2 1.5 1.9 8.1 8.1 25.0 6.1 23.1 3.0 2.1 4.9 8.2 4.0 1.5 1.5 11.3 4.8 5.1 13.0 18.6 4.2 6.5 18.7 8.5 3.6 5.3 3.6 10.4 8.2 1.7 4.4 64.1 5.7 11.0 11.1 9.0 7.0 6.2 6.9 10.5 6.2 6.6 8.3 9.4 2.5 4.6 2.1 7.9 22.7 8.5 3.6 11.1 21.0 5.8 10.8 11.2 6.0 4.7 5.4 5.7 7.2 6.3 6.2 6.1 7.8 12.9 4.9 17.6 7.6 3.7 13.8 6.8 2.4 6.3 8.4 20.6 17.6 6.4 7.5 6.8 10.2 6.3 4.9 4.1 5.0 24.3 15.0 5.2 15.8 8.4 4.4 9.3 8.5 18.7 3.6 5.5 3.5 4.2 4.6 5.2 5.7 3.6 5.3 4.3 7.7 3.6 6.0 6.5 3.9 3.6 1.6 1.8 2.7 1.9 1.7 1.1 1.6 1.6 1.8 1.5 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923739-43964488 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "liver: 31.1;retina: 39.3" "Cell line enhanced" "Detected in many" "AF22: 13.3;LHCN-M2: 15.0" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol Nucleoli "Mitochondria, Cytosol" "HPA058058: " "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.8 0.4 0.5 0.7 1.0 0.3 4.0 0.3 2.4 0.8 1.3 0.4 0.0 1.0 0.5 1.9 0.4 1.1 0.5 0.9 0.8 0.6 4.6 31.1 1.4 0.4 0.3 1.8 0.5 0.2 0.6 0.2 0.4 2.2 0.2 0.2 39.3 0.9 0.2 2.2 5.3 0.6 0.2 0.5 0.6 0.3 0.5 0.3 0.0 0.2 0.0 0.3 0.2 0.4 1.2 0.7 1.8 0.6 0.9 0.8 0.0 3.9 1.2 13.3 5.4 3.8 4.2 0.4 2.4 1.4 3.3 7.1 3.8 7.0 0.0 2.0 4.0 3.3 8.3 3.9 2.7 0.0 0.7 0.2 3.1 7.1 6.1 0.0 0.2 4.8 3.0 10.4 0.5 0.4 0.0 0.0 15.0 0.6 0.2 0.0 9.1 0.0 0.0 7.2 0.1 1.4 0.2 1.2 0.1 2.7 1.0 3.7 4.2 4.5 0.4 1.3 4.0 0.1 0.1 0.0 0.0 0.0 11.4 0.0 4.7 1.5 0.6 0.4 0.5 0.4 0.3 0.7 0.4 0.3 0.2 1.2 0.6 0.8 1.8 0.9 0.3 0.7 0.2 0.0 0.5 1.0 0.3 2.4 0.8 0.6 0.3 1.8 2.2 0.3 PNPLA4 "DXS1283E, GS2, iPLA2eta" ENSG00000006757 "Patatin like phospholipase domain containing 4" P41247 X 7898247-7927739 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA003656 Approved "Intracellular and membrane" "HPA003656: AB_1079033" "unprognostic (2.97e-1)" "unprognostic (2.45e-1)" "unprognostic (4.17e-3)" "unprognostic (3.08e-2)" "prognostic unfavourable (5.29e-4)" "prognostic unfavourable (5.37e-4)" "unprognostic (3.15e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (6.30e-2)" "unprognostic (7.83e-2)" "unprognostic (2.27e-1)" "prognostic favourable (2.23e-12)" "unprognostic (5.23e-2)" "unprognostic (6.71e-3)" "unprognostic (6.30e-2)" "unprognostic (2.12e-1)" 11.3 18.1 12.6 6.0 18.8 4.7 13.9 5.0 11.5 8.9 8.9 8.5 13.3 11.2 9.2 11.4 13.2 15.0 6.2 24.0 10.9 11.9 26.5 39.8 5.8 6.3 12.0 8.7 14.0 21.0 13.3 17.0 4.7 12.2 8.0 7.5 13.1 18.9 10.7 40.9 10.8 10.5 7.4 11.2 5.4 11.5 7.8 10.6 7.2 23.6 21.1 8.9 6.6 9.5 13.2 18.3 7.6 10.4 9.0 10.3 8.4 18.6 7.6 1.2 19.3 0.4 0.2 5.2 5.8 0.6 10.1 6.2 7.7 6.9 5.9 0.0 1.9 11.0 0.0 19.5 17.3 0.2 13.7 4.2 14.8 16.1 12.8 7.3 6.2 13.2 20.0 5.1 12.1 7.0 16.4 0.2 0.1 4.9 0.1 7.2 20.4 16.3 0.1 0.1 6.5 13.3 8.5 11.1 5.6 17.6 7.3 9.9 11.3 5.5 4.0 0.1 5.1 15.5 0.1 8.9 0.1 11.1 0.1 0.1 1.6 5.2 9.8 7.6 5.4 10.4 6.2 12.3 7.8 5.9 18.3 13.2 10.3 9.8 0.7 9.0 9.7 13.5 4.8 8.4 12.6 18.8 5.0 11.5 10.9 11.9 12.0 8.7 12.2 10.6 PNPLA6 "iPLA2delta, NTE, SPG39, sws" ENSG00000032444 "Patatin like phospholipase domain containing 6" Q8IY17 19 7534004-7561764 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation, Dwarfism, Hereditary spastic paraplegia, Hypogonadotropic hypogonadism, Mental retardation, Neurodegeneration, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007522 Uncertain "HPA007522: AB_1079649" "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" "unprognostic (3.23e-2)" "unprognostic (2.78e-1)" "prognostic favourable (5.25e-4)" "unprognostic (3.53e-3)" "unprognostic (1.50e-1)" "unprognostic (2.07e-2)" "unprognostic (1.62e-1)" "prognostic favourable (3.51e-5)" "unprognostic (3.36e-1)" "prognostic favourable (7.53e-4)" "unprognostic (3.10e-3)" "unprognostic (3.50e-1)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" 12.9 19.7 25.9 25.0 29.3 22.3 17.8 22.1 35.8 10.2 15.9 26.1 10.0 26.3 13.7 6.3 16.4 12.6 14.0 12.0 22.6 19.1 17.1 13.7 30.4 17.6 36.3 19.2 12.5 14.2 15.6 21.6 13.9 29.2 13.4 8.9 15.8 13.7 14.3 27.0 15.3 28.7 14.5 23.5 28.3 12.2 31.3 33.0 7.1 14.7 6.1 8.8 15.9 14.7 3.8 7.3 21.8 19.0 5.0 3.9 4.1 13.0 31.6 6.2 15.0 10.9 15.8 14.4 17.0 17.5 13.3 12.3 7.4 18.1 10.8 29.0 22.0 16.8 5.3 16.0 6.9 26.3 12.2 7.1 16.9 5.5 12.6 7.9 22.3 13.7 9.3 17.1 9.9 26.1 5.8 14.9 11.8 6.2 8.7 10.4 6.8 29.0 7.0 3.7 12.7 11.8 12.5 7.9 13.7 14.5 6.6 18.5 5.8 11.4 27.6 16.1 9.5 22.1 17.8 17.7 11.4 4.8 27.1 9.4 15.1 7.9 6.1 21.8 3.5 12.1 3.5 3.8 2.5 3.8 7.3 2.8 2.2 2.9 1.9 5.0 19.0 2.4 3.9 4.1 25.9 29.3 22.1 35.8 22.6 19.1 36.3 19.2 29.2 33.0 PNPLA8 "IPLA2-2, IPLA2G, iPLA2gamma" ENSG00000135241 "Patatin like phospholipase domain containing 8" Q9NP80 7 108470422-108569666 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020083 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA020083: AB_1851849" "unprognostic (4.48e-2)" "unprognostic (3.37e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (4.61e-1)" "unprognostic (2.73e-2)" "unprognostic (3.48e-2)" "unprognostic (3.32e-1)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (2.49e-1)" "prognostic favourable (1.86e-6)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (4.28e-3)" "unprognostic (1.24e-1)" 21.5 35.7 29.3 12.4 28.9 51.5 15.0 15.6 27.2 15.4 13.4 9.5 9.3 8.6 13.4 13.7 18.3 9.7 15.9 17.9 23.0 22.1 23.1 24.6 16.7 12.0 20.7 17.5 15.6 10.1 20.7 33.4 25.2 23.2 14.4 11.4 6.0 11.4 13.9 29.8 11.4 10.8 15.3 20.3 19.5 11.1 10.8 21.1 16.1 22.6 13.0 15.3 22.5 12.8 20.0 19.3 16.7 26.8 14.6 12.5 13.7 14.0 6.3 11.2 10.0 25.0 17.2 16.6 13.4 23.7 11.0 18.4 6.1 8.1 7.8 16.9 13.1 5.3 19.0 8.5 16.8 11.7 5.2 5.3 10.4 4.5 18.3 3.7 11.1 15.6 16.2 14.8 13.7 14.8 6.3 22.5 13.7 9.2 8.6 8.8 4.9 9.0 3.2 11.8 16.6 13.2 17.8 9.3 13.1 12.8 13.9 16.0 5.8 6.3 12.0 18.2 8.1 27.0 7.3 19.1 19.3 11.6 17.3 5.7 11.7 14.1 19.7 16.7 10.5 21.8 12.5 20.0 10.3 10.3 19.3 18.7 11.2 10.7 16.5 14.6 26.8 7.6 12.5 13.7 29.3 28.9 15.6 27.2 23.0 22.1 20.7 17.5 23.2 21.1 PNPO PDXPO ENSG00000108439 "Pyridoxamine 5'-phosphate oxidase" Q9NVS9 17 47941506-47949308 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Pyridoxine biosynthesis" Oxidoreductase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 64.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023204, HPA027776" Enhanced Enhanced Nucleoplasm,Cytosol 150000 "Nucleoplasm, Cytosol" "HPA023204: AB_1855506, HPA027776: AB_10601246" "unprognostic (1.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (1.41e-1)" "unprognostic (2.62e-1)" "unprognostic (1.97e-2)" "unprognostic (6.65e-2)" "unprognostic (8.34e-2)" "unprognostic (2.02e-3)" "unprognostic (7.47e-3)" "unprognostic (8.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.74e-1)" 6.0 13.1 9.9 5.1 13.0 2.9 8.6 8.3 16.5 6.2 7.0 8.6 6.9 8.5 4.2 9.6 8.1 8.4 10.1 10.2 8.7 12.0 26.0 64.7 5.3 7.7 11.2 9.9 8.0 13.7 17.3 7.4 5.8 11.1 6.9 7.4 8.4 8.3 7.1 14.7 5.5 9.6 5.2 7.1 6.8 6.7 6.4 6.0 5.2 14.4 8.2 6.1 5.4 5.2 6.8 12.2 2.4 16.4 7.7 8.2 8.7 17.5 14.5 1.1 2.7 7.4 5.7 0.0 5.9 3.9 6.7 5.8 23.8 13.0 16.7 28.5 5.9 10.6 9.1 16.2 9.7 20.3 7.8 11.8 6.8 24.7 8.0 10.4 8.1 7.6 12.7 12.4 15.4 8.7 11.1 5.8 7.8 13.1 10.5 3.4 2.1 18.0 8.9 5.1 12.2 18.5 9.1 5.9 4.9 5.4 8.8 5.0 15.6 3.8 9.1 10.8 6.3 10.7 12.4 13.8 15.2 8.8 8.8 9.1 5.5 2.1 11.0 2.4 6.8 16.4 8.0 6.8 6.2 7.4 12.2 5.7 8.2 7.9 1.1 7.7 10.4 8.9 6.4 8.7 9.9 13.0 8.3 16.5 8.7 12.0 11.2 9.9 11.1 6.0 PNPT1 "DFNB70, old-35, OLD35, PNPase" ENSG00000138035 "Polyribonucleotide nucleotidyltransferase 1" Q8TCS8 2 55634265-55693910 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transport" "Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, RNA-binding, Transferase" "Deafness, Disease mutation, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033424, HPA034602, HPA034603" Supported Enhanced Mitochondria Mitochondria "CAB033424: AB_2299801, HPA034602: AB_2674243, HPA034603: AB_10603130" "unprognostic (9.09e-2)" "unprognostic (7.40e-2)" "unprognostic (2.30e-1)" "prognostic unfavourable (5.57e-4)" "unprognostic (3.40e-2)" "unprognostic (1.03e-2)" "prognostic unfavourable (1.95e-7)" "unprognostic (1.88e-1)" "unprognostic (5.93e-3)" "unprognostic (5.23e-2)" "prognostic unfavourable (5.44e-5)" "unprognostic (2.19e-2)" "unprognostic (2.11e-2)" "unprognostic (6.92e-2)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (1.21e-1)" 11.1 11.7 13.3 6.5 21.7 11.7 10.8 13.3 18.8 5.7 8.2 12.8 5.4 5.7 8.3 8.8 9.5 7.9 5.8 11.0 12.4 10.9 9.8 11.4 9.1 7.1 24.1 7.4 6.9 9.1 7.4 14.3 5.1 15.2 7.7 10.1 4.2 9.0 6.3 23.5 10.1 7.0 7.9 17.6 10.4 7.6 13.5 22.5 9.6 10.0 7.8 5.9 5.3 7.4 9.8 7.4 6.1 6.5 3.8 8.6 4.7 6.7 3.6 5.0 2.3 3.6 6.3 6.7 10.0 6.1 15.9 10.7 10.5 3.2 14.1 4.2 4.7 5.4 6.4 7.8 7.4 5.0 14.2 8.1 4.6 5.3 9.5 18.3 5.5 7.0 5.4 6.6 5.7 4.9 8.5 3.2 6.3 3.8 11.2 12.8 12.1 6.1 11.1 8.4 12.4 6.7 4.2 12.2 7.3 3.6 11.1 12.2 3.0 8.1 5.1 3.8 3.2 3.3 10.2 14.3 1.1 3.0 7.2 16.0 6.4 4.2 6.5 6.1 8.1 5.7 4.8 5.4 3.7 8.6 2.8 9.8 6.9 7.9 6.1 3.8 5.1 7.4 2.4 4.7 13.3 21.7 13.3 18.8 12.4 10.9 24.1 7.4 15.2 22.5 POFUT1 "FUT12, KIAA0180, O-Fuc-T, O-FUT" ENSG00000101346 "Protein O-fucosyltransferase 1" Q9H488 20 32207880-32238667 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism, Notch signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Lineage enriched" "Detected in all" 4 "monocytes: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054519, HPA059935" Approved Approved Centrosome "Intracellular and membrane" 140000 Centrosome "HPA054519: , HPA059935: " "unprognostic (6.61e-2)" "unprognostic (4.10e-3)" "unprognostic (8.83e-2)" "unprognostic (5.51e-3)" "unprognostic (6.90e-2)" "unprognostic (1.62e-1)" "unprognostic (4.65e-1)" "unprognostic (8.51e-2)" "unprognostic (1.84e-1)" "unprognostic (5.57e-2)" "unprognostic (3.01e-1)" "unprognostic (2.19e-1)" "unprognostic (6.76e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-2)" "unprognostic (5.86e-3)" 15.9 13.5 8.2 15.5 8.9 7.4 19.4 6.6 11.3 15.5 20.2 13.1 10.4 16.4 18.1 19.6 13.9 17.4 23.6 20.1 7.5 6.3 18.8 44.6 14.8 22.2 8.8 6.6 18.3 24.6 19.2 11.3 22.4 7.8 16.0 16.0 16.9 13.3 16.0 13.5 13.3 27.5 20.8 7.7 12.4 12.5 16.5 7.0 12.7 20.1 13.9 13.0 15.7 12.6 2.8 3.9 3.3 16.4 1.7 3.3 3.2 15.0 12.1 10.5 11.5 18.1 17.7 19.7 15.6 18.6 26.4 17.4 36.2 20.4 10.2 23.6 17.4 16.8 10.1 19.3 23.0 5.2 6.3 15.2 11.1 16.4 14.1 13.0 9.7 15.5 15.3 20.0 13.1 14.7 11.4 5.8 18.4 7.4 8.9 10.0 5.4 19.7 7.5 28.0 9.4 8.1 10.0 6.9 8.9 35.9 10.0 13.3 14.8 15.6 12.7 38.4 14.3 24.0 26.5 7.2 9.1 9.4 23.2 45.3 24.2 3.3 4.4 2.1 2.9 12.8 3.3 2.8 2.6 2.7 3.9 2.4 3.3 2.4 0.9 1.7 16.4 2.9 2.7 3.2 8.2 8.9 6.6 11.3 7.5 6.3 8.8 6.6 7.8 7.0 POFUT2 "C21orf80, FUT13, KIAA0958" ENSG00000186866 "Protein O-fucosyltransferase 2" Q9Y2G5 21 45263928-45287898 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044297 Uncertain "Intracellular and membrane" "HPA044297: AB_10965176" "unprognostic (1.32e-2)" "unprognostic (1.65e-3)" "prognostic unfavourable (4.55e-7)" "unprognostic (1.49e-2)" "unprognostic (4.09e-3)" "unprognostic (5.03e-2)" "prognostic unfavourable (2.78e-4)" "unprognostic (2.62e-1)" "unprognostic (2.15e-1)" "unprognostic (4.16e-2)" "unprognostic (4.20e-3)" "unprognostic (1.48e-2)" "prognostic unfavourable (8.66e-12)" "unprognostic (1.56e-2)" "unprognostic (2.53e-1)" "unprognostic (3.91e-3)" "unprognostic (5.25e-2)" 12.9 15.3 11.3 13.1 12.4 14.8 16.1 8.7 11.9 15.2 12.8 14.5 12.0 11.6 19.7 23.2 7.0 16.3 15.5 13.7 12.1 11.7 13.7 14.5 16.1 8.7 13.5 7.3 24.6 17.3 12.7 28.1 20.6 12.2 15.3 8.0 16.6 17.1 15.7 6.3 8.3 11.7 15.0 8.5 12.8 13.3 24.2 10.0 7.7 19.4 8.9 8.6 12.0 12.9 1.5 2.0 3.8 1.9 1.6 2.6 1.5 4.2 4.8 9.6 10.7 17.6 16.4 4.5 24.4 19.8 11.7 17.2 10.3 7.4 3.0 18.5 40.6 4.4 5.7 9.8 12.7 5.0 6.7 6.0 6.8 8.2 20.3 4.4 8.0 11.6 6.6 14.4 7.8 11.4 5.6 4.9 11.7 4.4 2.2 7.4 12.8 7.0 4.5 2.9 3.8 6.2 4.0 4.2 6.2 14.4 8.8 8.8 6.4 6.4 12.1 8.5 8.4 13.5 10.8 12.1 6.3 2.4 18.0 5.6 13.7 1.7 1.7 3.8 1.7 1.9 2.6 1.1 1.9 1.5 0.5 1.5 2.2 2.2 2.5 1.6 1.5 2.0 1.7 1.5 11.3 12.4 8.7 11.9 12.1 11.7 13.5 7.3 12.2 10.0 POGLUT1 "9630046K23Rik, C3orf9, hCLP46, KDELCL1, KTELC1, MDS010, MDSRP, MGC32995, Rumi" ENSG00000163389 "Protein O-glucosyltransferase 1" Q8NBL1 3 119468938-119494708 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Gastrulation "Developmental protein, Glycosyltransferase, Transferase" "Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037855, HPA037856" Approved Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" "Endoplasmic reticulum" Cytosol "HPA037855: AB_10672728, HPA037856: AB_2732477" "unprognostic (2.43e-1)" "unprognostic (5.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-1)" "unprognostic (2.81e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (6.52e-3)" "unprognostic (1.31e-2)" "prognostic unfavourable (7.02e-7)" "unprognostic (3.08e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-3)" "prognostic favourable (2.23e-4)" 11.9 12.1 7.6 10.7 12.0 3.9 10.9 13.9 10.6 10.1 9.5 9.8 27.4 5.9 13.7 11.7 9.3 10.1 6.9 8.3 7.3 8.9 8.3 10.3 9.1 14.3 15.0 5.6 10.5 29.2 12.1 14.5 11.5 10.9 9.4 10.9 8.7 7.8 25.7 5.1 14.0 12.1 15.2 14.0 14.9 8.2 4.7 8.9 11.7 8.6 4.1 15.6 10.6 10.2 9.9 14.3 9.4 11.5 19.8 16.0 10.3 7.4 5.0 8.7 9.6 22.0 12.6 6.2 11.9 12.2 9.7 13.3 8.1 4.9 11.5 16.2 15.0 8.8 11.6 11.8 15.4 9.9 7.5 13.5 7.9 8.8 14.3 14.8 15.9 12.9 7.7 9.6 13.5 11.0 7.3 14.1 9.8 7.5 8.4 14.3 8.9 9.2 8.4 8.8 16.9 8.4 9.6 9.5 14.6 5.7 3.6 9.2 9.5 12.4 13.9 9.5 5.9 2.8 6.1 19.4 16.8 15.7 8.3 15.0 13.4 1.9 11.5 9.4 12.0 10.8 13.8 9.9 13.6 12.5 14.3 7.0 16.0 15.2 0.9 19.8 7.0 8.0 14.7 10.3 7.6 12.0 13.9 10.6 7.3 8.9 15.0 5.6 10.9 8.9 POLA1 "NSX, p180, POLA" ENSG00000101868 "DNA polymerase alpha 1, catalytic subunit" P09884 X 24693919-24996986 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA replication, Host-virus interaction" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002947, CAB012274" Supported Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB012274: , HPA002947: AB_1079652" "unprognostic (6.92e-2)" "unprognostic (4.43e-3)" "unprognostic (3.27e-3)" "unprognostic (1.53e-2)" "unprognostic (2.53e-1)" "unprognostic (1.49e-1)" "prognostic unfavourable (4.80e-5)" "unprognostic (1.87e-1)" "unprognostic (9.25e-3)" "unprognostic (2.48e-2)" "unprognostic (8.41e-2)" "unprognostic (7.42e-2)" "unprognostic (2.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-2)" "unprognostic (3.08e-1)" 10.5 5.5 8.0 15.0 10.2 14.3 10.9 12.0 9.6 10.1 9.7 11.8 5.8 5.7 11.2 7.7 10.2 8.9 5.5 9.3 7.8 6.6 6.1 4.9 7.2 12.7 10.3 4.5 12.9 7.3 8.5 8.5 10.7 8.7 7.3 11.0 7.5 7.9 9.3 22.4 9.3 7.5 9.7 13.1 9.0 7.9 5.7 10.0 30.1 7.0 8.5 14.7 9.9 10.6 4.6 2.5 1.2 4.6 2.7 3.8 1.7 14.0 10.5 13.9 11.2 2.6 3.1 3.1 10.5 5.8 11.3 13.0 8.7 7.4 18.0 3.6 4.5 11.6 26.4 8.5 15.3 9.3 11.2 13.4 20.5 6.5 1.1 17.5 7.2 2.0 1.8 14.1 4.1 5.8 12.3 9.2 7.8 9.8 19.0 5.9 13.5 8.8 17.1 36.5 13.6 4.1 9.3 12.6 7.8 12.4 5.9 5.6 11.6 5.8 4.6 10.0 6.9 19.1 10.0 5.5 7.9 14.5 5.8 8.3 11.1 0.0 2.0 1.2 3.0 4.6 2.9 4.6 3.4 3.8 2.5 3.2 2.4 2.4 0.6 2.7 1.3 1.6 3.6 1.7 8.0 10.2 12.0 9.6 7.8 6.6 10.3 4.5 8.7 10.0 POLB ENSG00000070501 "DNA polymerase beta" P06746 8 42338454-42371808 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.6" "Cell line enhanced" "Detected in all" "HMC-1: 79.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 73.6" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011616, HPA049104" Enhanced Uncertain Vesicles Vesicles "CAB011616: AB_731977, HPA049104: " "unprognostic (1.67e-1)" "unprognostic (2.68e-3)" "unprognostic (2.43e-1)" "prognostic unfavourable (1.46e-4)" "unprognostic (8.49e-2)" "unprognostic (2.64e-2)" "unprognostic (4.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.31e-2)" "unprognostic (1.99e-1)" "unprognostic (4.57e-2)" "unprognostic (4.77e-1)" "prognostic unfavourable (2.15e-5)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (4.22e-2)" "prognostic favourable (5.65e-4)" 5.5 8.6 10.1 9.5 10.7 21.9 13.5 73.6 16.6 7.0 5.5 5.8 6.0 4.9 6.2 11.2 12.4 6.3 11.3 16.3 9.8 9.6 7.2 15.8 9.1 11.8 8.4 10.3 10.3 7.7 10.3 11.6 5.0 10.9 11.4 6.3 6.8 22.1 6.9 36.6 10.8 4.9 6.6 10.0 8.1 6.4 29.5 5.4 9.7 7.7 17.2 10.1 11.5 9.2 4.9 33.8 25.1 9.4 7.9 7.2 4.2 10.8 6.5 11.3 22.5 6.3 6.0 9.5 6.9 8.0 11.5 10.6 9.1 12.7 9.8 8.8 4.4 5.5 9.4 8.1 14.2 6.4 10.2 7.1 5.4 12.3 9.7 5.0 79.7 5.3 9.6 8.5 10.0 8.7 15.5 6.3 11.1 6.4 20.7 14.2 15.2 7.5 11.9 11.4 8.4 21.6 8.8 6.4 11.7 8.2 5.5 20.9 14.7 8.6 4.8 5.5 7.7 13.7 6.7 9.2 15.3 13.9 5.5 10.7 14.3 12.5 5.9 17.3 4.9 7.2 5.5 4.9 5.2 5.3 6.1 4.5 5.8 5.4 25.1 7.9 9.4 33.8 7.2 4.2 10.1 10.7 73.6 16.6 9.8 9.6 8.4 10.3 10.9 5.4 POLD1 "CDC2, POLD" ENSG00000062822 "DNA polymerase delta 1, catalytic subunit" P28340 19 50384204-50418016 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004375, HPA046524" Supported Supported Nucleoplasm Nucleoplasm "CAB004375: AB_675487, HPA046524: " "unprognostic (2.45e-1)" "unprognostic (7.02e-3)" "unprognostic (1.59e-1)" "unprognostic (4.35e-2)" "unprognostic (2.55e-1)" "unprognostic (1.85e-2)" "prognostic unfavourable (2.87e-6)" "unprognostic (4.12e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-1)" "unprognostic (5.08e-1)" "unprognostic (3.92e-3)" "unprognostic (4.01e-3)" "unprognostic (1.28e-2)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "unprognostic (3.70e-2)" 7.9 5.7 5.4 18.3 9.9 31.6 6.6 9.4 5.4 8.2 10.0 6.1 5.9 6.8 9.5 7.2 11.3 6.9 5.2 5.5 4.4 3.2 7.6 9.3 10.9 15.7 7.0 3.6 8.2 8.4 5.2 5.1 10.9 6.7 6.3 5.2 4.9 8.1 5.4 7.2 13.1 9.9 6.2 7.7 14.1 6.5 13.2 6.5 27.4 12.1 8.1 14.2 5.9 7.8 9.3 10.5 2.1 8.5 5.4 7.3 5.6 18.1 25.0 13.7 7.9 1.7 1.5 14.1 11.3 5.0 13.9 17.8 13.6 14.4 26.0 6.4 3.4 14.9 16.2 12.3 4.8 21.9 43.5 22.6 24.2 17.9 1.6 21.5 20.0 2.9 3.8 12.6 3.8 7.1 24.3 20.2 5.8 12.2 33.3 33.7 16.1 18.2 33.1 23.0 22.8 4.4 17.3 14.3 12.9 11.2 13.8 2.6 7.6 20.4 5.6 7.1 23.0 7.6 19.8 19.1 31.4 27.8 7.7 24.3 6.9 1.6 6.2 2.1 7.3 7.8 6.2 7.8 6.5 5.9 5.7 9.3 6.5 5.9 1.1 5.4 8.5 10.5 4.5 5.6 5.4 9.9 9.4 5.4 4.4 3.2 7.0 3.6 6.7 6.5 POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687365 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 34.8" "Cell type enhanced" "Detected in some" "NK-cell: 4.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA058210, HPA067385" Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA058210: , HPA067385: " "unprognostic (1.60e-1)" "unprognostic (1.77e-3)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-2)" "unprognostic (3.96e-3)" "unprognostic (2.23e-1)" "prognostic unfavourable (1.44e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "prognostic unfavourable (3.19e-8)" "unprognostic (8.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" 6.1 3.4 6.7 10.2 4.4 29.3 6.2 34.8 14.4 7.0 6.6 2.0 7.6 7.3 6.1 4.4 7.5 6.2 6.5 4.7 5.6 1.6 3.8 8.6 5.4 8.2 3.3 4.3 8.7 6.8 3.6 3.1 6.5 5.1 6.8 7.7 4.3 8.7 7.4 8.9 17.9 8.5 6.8 3.7 16.7 7.8 25.6 4.4 29.8 5.1 6.0 10.3 6.7 8.7 0.5 1.7 0.8 0.8 4.8 0.7 0.5 11.1 14.9 22.1 10.6 4.7 3.6 19.7 11.4 5.2 13.7 10.0 18.0 6.6 12.8 4.8 6.2 15.5 15.4 7.7 8.4 5.9 19.5 20.2 19.2 8.8 0.9 15.8 11.6 2.8 3.0 14.2 4.7 4.8 22.6 7.2 6.7 18.1 25.9 28.9 17.2 8.9 21.5 12.5 5.8 4.3 18.3 18.5 10.6 13.3 10.9 2.5 16.1 9.8 4.3 12.5 12.8 9.4 11.5 9.6 6.5 20.1 6.8 21.9 8.8 0.0 0.3 0.8 0.5 0.1 0.7 0.5 0.3 0.4 0.7 0.3 0.5 0.3 0.1 4.8 0.8 1.7 0.6 0.5 6.7 4.4 34.8 14.4 5.6 1.6 3.3 4.3 5.1 4.4 POLE2 DPE2 ENSG00000100479 "DNA polymerase epsilon 2, accessory subunit" P56282 14 49643555-49688422 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA replication" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.6;lymphoid tissue: 17.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027555 Uncertain Supported "Nucleoplasm,Nuclear bodies,Vesicles" "Nucleoplasm, Nuclear bodies" Vesicles "HPA027555: AB_10610282" "unprognostic (1.42e-1)" "unprognostic (6.57e-3)" "unprognostic (3.53e-2)" "unprognostic (7.44e-2)" "unprognostic (2.04e-2)" "unprognostic (4.99e-3)" "unprognostic (7.60e-3)" "unprognostic (2.32e-3)" "unprognostic (1.10e-3)" "unprognostic (2.69e-2)" "unprognostic (1.88e-2)" "unprognostic (1.37e-3)" "unprognostic (5.13e-11)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.50e-3)" 3.3 2.2 1.5 11.6 2.8 17.6 3.4 1.7 1.6 4.4 4.2 1.1 1.5 2.6 2.8 3.5 9.0 2.4 2.3 1.6 1.0 1.2 2.5 5.1 2.2 5.3 1.1 0.3 2.7 5.0 1.4 2.5 4.1 1.4 2.1 5.2 2.6 2.6 0.7 1.1 3.7 7.7 2.9 2.7 5.4 3.0 5.3 2.4 17.6 1.6 10.3 8.4 2.1 4.2 1.2 0.9 0.7 0.0 3.2 2.7 0.5 17.1 8.8 16.7 7.7 0.8 4.9 8.5 9.8 5.0 15.6 18.1 8.8 13.5 10.7 5.6 5.5 10.6 16.7 6.0 18.5 12.5 9.2 15.9 9.7 10.9 0.4 18.9 6.9 1.4 0.4 8.5 1.4 9.0 13.9 6.9 15.6 15.0 19.2 12.4 9.8 20.6 16.4 15.4 9.7 5.6 9.7 12.0 6.9 9.9 5.8 3.1 11.7 6.7 3.2 2.5 18.6 10.4 7.7 5.0 10.2 24.7 4.7 14.0 10.0 0.0 0.0 0.7 0.9 0.0 0.7 1.2 0.9 1.7 0.6 1.2 0.1 0.8 0.0 3.2 0.0 0.9 2.7 0.5 1.5 2.8 1.7 1.6 1.0 1.2 1.1 0.3 1.4 2.4 POLE3 "CHARAC17, CHRAC17, p17, Ybl1" ENSG00000148229 "DNA polymerase epsilon 3, accessory subunit" Q9NRF9 9 113407235-113410672 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047945 Uncertain Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA047945: " "unprognostic (9.55e-2)" "unprognostic (3.39e-3)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.86e-2)" "prognostic unfavourable (8.35e-4)" "unprognostic (1.04e-2)" "unprognostic (1.60e-2)" "unprognostic (1.10e-1)" "unprognostic (4.59e-3)" "unprognostic (2.31e-3)" "unprognostic (1.75e-2)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" 16.9 23.9 18.2 22.0 18.5 56.3 19.3 36.0 25.0 17.0 17.6 15.8 12.5 15.1 18.2 16.5 27.8 17.6 17.0 17.9 16.1 14.8 14.3 29.5 15.8 29.0 15.1 18.5 15.4 20.8 13.1 8.4 21.2 20.0 15.9 20.3 12.4 17.9 16.3 48.3 24.7 17.3 16.9 16.9 26.8 17.2 29.9 15.9 35.0 16.3 27.3 32.4 18.8 16.7 34.9 33.5 34.3 34.4 28.0 44.0 47.7 15.7 19.7 13.9 20.8 7.9 7.1 12.2 21.1 10.8 23.9 18.9 18.2 14.4 57.4 13.1 12.3 27.1 27.0 23.2 22.1 10.9 16.3 29.8 20.4 18.6 8.5 61.7 18.0 8.1 16.0 20.7 26.8 16.5 41.5 32.1 16.6 40.1 42.3 33.2 17.9 35.7 43.4 57.9 32.2 10.4 15.1 30.1 17.4 30.6 19.4 16.5 29.0 27.8 13.6 17.8 24.1 22.4 36.0 16.8 54.9 77.4 16.2 36.5 21.2 25.4 34.0 34.3 35.5 34.4 44.0 34.9 34.0 33.7 33.2 33.5 36.9 34.3 7.2 28.0 26.6 33.5 39.0 47.7 18.2 18.5 36.0 25.0 16.1 14.8 15.1 18.5 20.0 15.9 POLE4 p12 ENSG00000115350 "DNA polymerase epsilon 4, accessory subunit" Q9NR33 2 74958492-74970128 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054979, HPA071815" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA054979: , HPA071815: " "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.19e-2)" "unprognostic (4.85e-2)" "unprognostic (1.59e-2)" "prognostic unfavourable (6.49e-4)" "unprognostic (3.09e-1)" "unprognostic (1.99e-1)" "unprognostic (2.95e-1)" "unprognostic (1.39e-2)" "unprognostic (4.44e-2)" "unprognostic (8.64e-3)" "unprognostic (6.61e-2)" "unprognostic (3.73e-1)" "unprognostic (3.47e-2)" "unprognostic (1.95e-1)" 19.2 14.5 23.6 15.2 17.3 27.1 21.4 4.4 15.5 18.4 13.4 8.6 7.0 9.0 10.4 9.0 10.0 9.7 13.1 18.1 15.9 10.6 11.6 18.8 10.7 17.0 13.9 12.6 12.8 12.5 2.8 3.9 9.6 12.2 12.0 8.8 13.9 16.2 11.2 28.1 8.1 12.4 14.1 11.7 12.2 12.5 11.0 10.0 5.5 13.1 15.1 10.4 13.9 31.9 14.7 14.7 8.0 22.2 4.4 9.9 12.3 11.7 11.2 1.0 1.0 3.8 8.6 0.0 8.0 9.9 12.8 10.9 14.9 5.2 11.5 6.7 9.0 5.3 5.3 6.6 15.0 5.2 14.4 8.9 6.5 14.7 13.9 12.6 14.1 8.7 13.0 5.3 11.8 5.5 10.9 6.8 9.7 11.4 3.7 35.6 7.8 21.1 4.5 9.6 9.3 10.6 0.3 3.5 5.3 11.0 4.6 6.3 3.4 4.1 6.2 2.9 3.3 2.0 7.6 2.4 1.6 4.2 10.5 18.9 14.1 2.3 22.2 8.0 6.3 13.2 7.0 14.7 8.9 7.8 12.9 13.7 9.9 6.9 1.6 4.4 12.4 14.7 8.5 12.3 23.6 17.3 4.4 15.5 15.9 10.6 13.9 12.6 12.2 10.0 POLG "POLG1, POLGA" ENSG00000140521 "DNA polymerase gamma, catalytic subunit" P54098 15 89305198-89334861 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease mutation, Epilepsy, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056821, HPA078482" Approved Supported Mitochondria Mitochondria "HPA056821: , HPA078482: " "unprognostic (1.87e-1)" "unprognostic (4.71e-2)" "unprognostic (2.61e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (3.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.63e-1)" "unprognostic (1.41e-1)" "prognostic unfavourable (5.73e-4)" "unprognostic (2.65e-3)" "unprognostic (1.58e-2)" "unprognostic (4.29e-2)" "unprognostic (2.07e-1)" "unprognostic (3.45e-1)" 17.8 15.2 19.8 19.0 19.2 16.8 24.6 23.2 20.9 14.1 16.0 14.6 13.6 20.0 17.6 9.0 20.7 14.3 14.0 17.4 16.7 8.8 14.9 19.5 17.8 21.8 17.3 15.3 16.6 17.9 17.7 12.9 16.2 16.0 15.4 13.2 10.5 15.9 12.0 35.9 19.8 18.5 14.1 12.7 22.9 16.2 12.4 17.3 29.0 15.4 12.1 19.2 16.5 18.9 6.0 9.0 9.0 6.5 9.2 10.9 6.7 6.8 13.0 9.0 11.7 14.7 9.4 11.5 13.7 7.3 14.1 11.1 19.0 17.2 10.8 21.2 10.8 14.9 24.0 11.6 4.7 23.3 20.6 16.4 13.7 6.8 12.5 15.2 27.1 8.5 17.0 9.7 8.3 16.8 14.4 12.2 11.4 12.1 17.3 15.5 8.1 5.8 17.7 11.0 15.3 8.0 16.8 20.0 7.3 19.5 14.3 15.9 11.9 17.1 12.5 19.1 13.2 28.0 13.1 13.1 7.6 15.0 12.2 17.5 15.2 4.9 6.3 9.0 9.2 6.5 8.0 3.3 7.6 10.9 9.0 6.0 6.6 6.9 2.3 9.2 5.2 6.0 4.3 6.7 19.8 19.2 23.2 20.9 16.7 8.8 17.3 15.3 16.0 17.3 POLG2 "HP55, MTPOLB" ENSG00000256525 "DNA polymerase gamma 2, accessory subunit" Q9UHN1 17 64477785-64497036 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease mutation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017030, HPA023202" Approved Approved "Nuclear bodies,Mitochondria" "Nuclear bodies" Mitochondria "CAB017030: , HPA023202: AB_1855523" "unprognostic (1.76e-1)" "unprognostic (2.20e-1)" "unprognostic (1.59e-1)" "unprognostic (7.02e-2)" "unprognostic (6.01e-2)" "unprognostic (2.91e-2)" "prognostic unfavourable (1.39e-6)" "unprognostic (4.38e-2)" "unprognostic (8.46e-2)" "unprognostic (3.14e-1)" "unprognostic (5.17e-3)" "prognostic unfavourable (6.59e-4)" "prognostic unfavourable (1.17e-5)" "unprognostic (5.17e-2)" "unprognostic (1.58e-1)" "unprognostic (2.88e-2)" "unprognostic (4.82e-2)" 6.7 9.3 5.4 17.5 10.0 8.1 8.2 10.9 8.7 7.7 7.8 7.0 11.1 7.9 10.2 6.8 6.4 7.5 7.9 7.3 5.6 4.4 7.8 7.8 10.4 12.2 10.8 5.2 13.0 9.4 5.0 9.9 6.9 8.7 8.0 5.7 5.8 8.6 11.9 10.7 10.5 8.4 9.3 5.6 11.5 6.9 24.2 7.9 9.8 9.6 5.4 13.3 6.6 11.5 12.2 10.5 6.5 8.2 6.0 12.2 4.4 6.7 8.3 6.0 7.4 5.7 4.6 7.3 4.0 3.8 6.1 5.3 8.6 5.4 12.4 4.9 2.1 5.6 8.2 3.8 7.7 3.5 9.4 8.4 10.0 8.5 6.4 11.9 9.4 4.6 4.4 4.9 7.3 4.4 14.7 4.8 5.9 9.0 12.6 15.7 6.3 9.3 11.8 19.6 13.1 5.6 2.0 8.4 9.4 3.2 7.3 7.4 7.1 10.0 4.9 6.6 8.9 5.7 10.4 8.5 5.7 9.4 5.2 11.1 4.6 6.5 5.9 6.5 7.9 3.5 7.5 12.2 8.8 7.6 10.5 12.1 12.2 11.6 1.2 6.0 8.2 4.8 8.4 4.4 5.4 10.0 10.9 8.7 5.6 4.4 10.8 5.2 8.7 7.9 POLH "RAD30A, XP-V" ENSG00000170734 "DNA polymerase eta" Q9Y253 6 43576150-43615660 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Disease mutation, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006721, HPA026762" Approved Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006721: AB_1847785, HPA026762: AB_10601248" "unprognostic (1.79e-1)" "unprognostic (7.29e-2)" "unprognostic (2.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.61e-1)" "unprognostic (5.11e-3)" "unprognostic (9.68e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (7.75e-2)" "unprognostic (4.11e-3)" "unprognostic (2.24e-1)" "unprognostic (9.50e-2)" "unprognostic (6.73e-2)" "unprognostic (8.77e-2)" "unprognostic (7.91e-2)" "unprognostic (6.02e-2)" 7.4 9.4 7.5 9.7 10.4 4.6 7.2 10.5 10.5 8.5 8.4 12.7 8.0 5.7 9.6 7.1 11.4 7.8 6.2 6.7 5.3 4.4 7.2 7.5 9.8 16.3 8.9 8.1 7.4 13.0 7.1 9.7 5.1 7.9 6.9 10.1 8.9 8.6 5.6 9.5 11.7 7.9 11.8 6.9 9.2 7.6 24.7 6.8 22.1 9.9 6.2 18.3 8.6 8.4 8.6 4.3 4.5 2.6 6.8 7.2 3.2 20.2 4.7 6.3 9.2 9.0 14.9 15.0 21.7 6.8 12.7 14.7 5.3 3.6 22.5 5.5 8.8 5.1 6.4 13.7 15.8 11.3 4.9 6.6 13.1 15.4 6.7 11.2 8.9 10.0 16.7 10.4 5.6 12.0 10.4 13.5 16.0 6.7 10.2 2.9 1.9 3.5 11.2 6.5 5.6 4.8 15.2 7.1 2.4 6.9 5.8 3.4 8.2 5.0 16.2 11.8 11.4 5.5 10.9 12.7 8.8 40.6 5.6 6.6 12.8 4.5 2.6 4.1 7.2 2.5 6.4 7.8 6.0 5.2 2.1 8.6 5.0 5.2 2.0 6.8 1.9 4.3 7.0 3.2 7.5 10.4 10.5 10.5 5.3 4.4 8.9 8.1 7.9 6.8 POLI "RAD30B, RAD3OB" ENSG00000101751 "DNA polymerase iota" Q9UNA4 18 54269404-54321266 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012000, HPA064696" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" "Nuclear speckles" "Cytoplasmic bodies" "HPA012000: AB_1847786, HPA064696: " "unprognostic (1.64e-1)" "unprognostic (5.79e-3)" "unprognostic (9.72e-3)" "unprognostic (4.92e-2)" "unprognostic (3.04e-1)" "unprognostic (4.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.05e-2)" "unprognostic (4.04e-3)" "unprognostic (2.22e-2)" "unprognostic (2.07e-3)" "unprognostic (1.30e-3)" "unprognostic (1.55e-1)" "unprognostic (4.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (6.99e-2)" 16.5 11.1 10.2 9.5 14.0 5.2 15.8 9.6 14.7 12.9 9.9 13.4 13.7 6.6 13.2 13.1 6.6 10.3 8.3 9.1 8.7 7.6 12.9 6.4 9.0 7.4 10.9 9.0 16.4 11.8 17.6 21.3 17.4 15.3 12.7 7.7 9.6 11.3 14.7 7.2 8.2 7.6 10.9 12.0 8.2 9.0 30.5 10.9 17.3 27.3 1.5 7.0 12.7 10.5 9.9 10.3 10.9 10.7 7.9 12.7 7.1 7.7 2.8 21.3 12.9 7.2 14.1 6.9 6.4 13.8 7.4 12.4 2.1 7.4 3.7 2.1 9.3 6.4 5.0 7.3 8.3 8.8 2.5 4.6 3.2 5.4 11.8 7.3 3.8 15.2 11.2 6.4 13.4 15.6 3.1 10.5 12.3 6.1 5.2 6.4 7.3 3.1 3.3 4.3 9.1 8.4 10.3 10.0 10.2 4.6 4.1 6.8 14.8 3.3 7.5 13.9 3.8 2.1 5.3 8.5 1.9 5.2 9.9 6.6 10.1 5.4 10.7 10.9 8.3 5.7 7.7 8.6 8.8 8.6 10.3 9.9 12.7 7.6 6.7 7.9 5.8 8.1 9.8 7.1 10.2 14.0 9.6 14.7 8.7 7.6 10.9 9.0 15.3 10.9 POLK "DINB1, DINP, POLQ" ENSG00000122008 "DNA polymerase kappa" Q9UBT6 5 75511756-75601144 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012035, HPA057303, HPA068117, HPA069375" Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA012035: , HPA057303: , HPA068117: , HPA069375: " "unprognostic (9.66e-2)" "unprognostic (5.29e-2)" "unprognostic (5.37e-2)" "unprognostic (2.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.66e-1)" "unprognostic (1.73e-2)" "unprognostic (7.76e-2)" "unprognostic (1.65e-2)" "unprognostic (6.29e-3)" "unprognostic (2.42e-1)" "unprognostic (5.93e-2)" "unprognostic (1.80e-2)" "unprognostic (9.96e-3)" "unprognostic (1.58e-1)" "unprognostic (9.64e-2)" "unprognostic (2.02e-1)" 14.7 12.7 10.1 8.6 12.9 6.3 13.4 17.0 13.4 18.1 10.7 8.8 13.6 6.3 21.3 12.1 11.7 10.5 9.5 11.4 14.1 10.5 12.6 12.3 12.2 9.2 14.1 12.9 15.5 11.1 18.5 23.9 15.2 17.2 13.9 8.1 6.5 10.2 10.5 15.2 10.3 9.2 15.4 16.9 13.1 9.0 9.8 12.4 12.1 18.8 9.3 8.9 12.7 10.2 7.0 7.5 6.0 13.3 4.6 4.5 2.5 6.4 6.6 4.1 5.2 5.4 10.9 3.5 12.3 8.7 9.6 10.0 4.2 5.2 6.6 10.1 8.1 2.5 3.8 4.2 11.5 7.3 4.4 6.0 5.8 1.9 10.4 3.8 4.9 5.0 5.2 7.7 5.3 8.0 5.3 3.9 9.0 0.5 7.5 3.1 1.5 3.9 3.2 10.5 4.6 5.8 2.2 4.2 4.6 9.2 2.5 3.3 3.6 3.7 10.0 7.0 3.6 3.3 7.0 4.5 4.1 5.9 4.7 6.1 12.0 5.7 7.1 3.4 3.3 7.9 2.9 7.0 3.7 4.0 6.1 5.4 4.5 3.0 6.0 4.6 13.3 7.5 4.1 2.5 10.1 12.9 17.0 13.4 14.1 10.5 14.1 12.9 17.2 12.4 POLL ENSG00000166169 "DNA polymerase lambda" Q9UGP5 10 101578882-101588270 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066704 Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" "Nucleoplasm, Golgi apparatus" "HPA066704: " "unprognostic (3.71e-3)" "unprognostic (6.93e-3)" "unprognostic (1.73e-2)" "unprognostic (2.47e-2)" "unprognostic (9.52e-2)" "unprognostic (1.80e-2)" "unprognostic (2.11e-2)" "unprognostic (1.24e-1)" "unprognostic (8.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.12e-2)" "unprognostic (7.19e-2)" "unprognostic (4.74e-2)" "unprognostic (1.06e-2)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" "unprognostic (1.64e-3)" 11.0 15.1 14.4 16.0 17.1 9.2 13.4 11.2 22.1 13.7 12.6 16.4 15.6 14.3 15.1 22.1 15.4 18.1 17.7 12.3 11.1 10.4 16.4 16.5 11.8 13.0 9.6 13.0 20.9 30.7 21.7 23.7 11.7 12.7 17.2 15.0 19.5 17.8 14.7 26.1 12.8 11.9 12.7 9.4 15.6 16.7 53.2 11.2 4.6 18.3 10.2 14.2 14.8 11.6 8.5 10.7 1.1 8.5 8.4 11.9 7.1 12.5 11.5 9.1 12.6 9.2 17.2 12.7 8.3 14.5 12.8 13.5 8.4 15.2 3.1 13.2 7.5 15.8 10.0 12.3 10.3 11.1 13.6 9.8 10.8 9.5 17.0 10.2 9.0 15.6 16.8 14.1 29.4 13.7 10.9 10.9 8.0 10.0 0.0 11.2 4.8 6.8 0.0 8.1 5.1 10.7 7.6 6.4 9.3 5.1 8.6 14.3 26.2 5.9 7.3 4.6 9.3 5.2 9.1 15.8 7.9 4.7 9.9 8.9 3.4 0.5 8.5 1.1 6.7 5.9 10.6 8.5 7.4 6.8 10.7 7.1 11.9 7.9 0.9 8.4 5.7 0.2 8.9 7.1 14.4 17.1 11.2 22.1 11.1 10.4 9.6 13.0 12.7 11.2 POLM Tdt-N ENSG00000122678 "DNA polymerase mu" Q9NP87 7 44072247-44082540 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 31.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 31.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058900, HPA066007" Supported Nucleoplasm Nucleoplasm "HPA058900: , HPA066007: " "unprognostic (2.44e-2)" "unprognostic (8.18e-2)" "unprognostic (2.21e-3)" "unprognostic (3.93e-2)" "unprognostic (5.40e-2)" "unprognostic (1.83e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (3.91e-1)" "unprognostic (9.36e-2)" "unprognostic (8.26e-2)" "unprognostic (2.46e-3)" "unprognostic (6.31e-2)" "unprognostic (1.47e-1)" "unprognostic (2.87e-1)" "unprognostic (3.87e-3)" 10.7 8.7 7.0 18.0 7.1 7.6 12.2 11.9 8.8 13.8 11.2 11.1 11.7 12.2 10.1 12.0 11.7 11.8 11.8 10.8 6.8 4.4 13.0 12.5 10.1 20.9 9.9 7.0 13.8 12.3 10.0 9.0 8.1 8.2 11.8 7.1 12.4 13.5 14.3 11.2 12.0 12.6 8.9 9.0 18.7 12.0 6.8 8.1 30.1 15.4 8.3 17.6 12.4 10.7 5.9 4.8 31.6 2.1 3.5 4.2 1.3 1.0 1.5 1.5 3.4 2.2 2.5 4.9 3.5 3.9 2.7 1.6 1.9 2.6 11.1 3.5 2.9 3.3 1.6 37.7 1.5 3.9 3.5 1.3 1.6 0.7 3.1 3.4 5.0 4.0 3.6 2.2 2.8 4.8 1.6 5.4 2.3 2.5 7.0 3.0 3.3 8.1 5.6 0.9 4.4 3.0 1.8 1.6 2.9 1.7 7.2 3.6 4.6 6.0 3.3 1.9 2.8 1.9 5.1 8.9 4.4 8.7 3.5 3.1 4.6 8.6 1.8 5.1 3.3 2.1 3.3 4.0 2.9 3.0 1.6 5.9 4.2 3.4 31.6 3.5 1.6 4.8 2.7 1.3 7.0 7.1 11.9 8.8 6.8 4.4 9.9 7.0 8.2 8.1 POLN ENSG00000130997 "DNA polymerase nu" Q7Z5Q5 4 2071918-2242121 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 5.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "eosinophil: 2.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035939, HPA035940" Enhanced Nucleoplasm Nucleoplasm "HPA035939: , HPA035940: " "unprognostic (8.52e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (1.45e-2)" "unprognostic (3.46e-1)" "unprognostic (2.70e-1)" "unprognostic (5.83e-2)" "unprognostic (2.23e-1)" "unprognostic (2.02e-3)" "unprognostic (1.25e-1)" "unprognostic (1.49e-3)" "unprognostic (9.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" 13.6 3.9 6.1 2.5 5.7 1.8 5.2 11.1 5.5 2.8 2.9 3.5 2.9 2.7 4.0 5.8 2.6 3.6 3.3 2.8 4.4 2.9 3.6 3.4 3.0 2.7 4.3 4.0 2.8 3.1 2.4 7.6 2.3 3.8 4.6 1.8 1.7 4.7 3.5 2.7 2.7 2.4 3.3 5.6 3.5 2.9 12.3 5.2 8.5 2.4 0.9 2.6 2.5 2.6 0.2 0.1 2.4 0.0 0.0 0.9 0.1 0.3 2.7 0.5 1.9 5.7 2.2 0.0 1.9 1.0 1.1 1.6 0.1 0.2 1.2 0.5 1.7 0.4 2.2 0.8 1.6 0.3 2.9 0.1 1.9 0.0 0.7 0.2 2.5 3.0 0.8 1.6 1.4 0.6 0.2 2.3 3.1 0.3 0.2 0.2 0.2 0.5 0.0 3.8 0.9 0.8 0.5 2.5 0.0 0.2 0.0 0.2 0.0 0.7 0.3 0.1 1.9 1.1 0.6 0.6 0.7 0.0 0.6 1.8 1.1 0.0 0.0 2.4 0.2 0.0 0.9 0.2 0.2 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.1 6.1 5.7 11.1 5.5 4.4 2.9 4.3 4.0 3.8 5.2 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.5;lymphoid tissue: 21.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 1.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 5.2" "HPA048931, HPA053359" Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA048931: , HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavourable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favourable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.5 0.8 0.2 8.2 0.7 9.5 0.6 0.6 0.4 0.9 3.5 0.2 0.8 2.0 0.9 0.6 6.0 0.3 0.4 0.8 0.3 0.2 0.4 0.6 0.9 4.7 0.3 0.0 0.4 0.4 0.0 0.2 2.8 0.3 0.4 3.7 0.1 1.1 0.8 1.2 2.4 3.9 0.5 0.4 2.6 1.1 5.8 0.6 21.4 0.3 5.6 7.5 0.6 1.7 0.5 1.1 1.6 0.4 0.0 0.4 0.0 13.3 9.1 7.8 5.5 0.7 0.9 7.1 6.3 2.4 7.5 10.1 7.2 5.0 15.9 2.9 3.4 10.6 9.2 4.1 12.8 4.6 5.0 10.2 5.6 4.5 0.0 11.0 9.3 0.1 0.3 6.8 4.2 3.7 6.7 12.1 7.8 5.2 9.9 6.4 7.4 4.4 8.4 9.4 5.6 2.4 7.7 4.3 3.8 7.3 4.0 2.6 3.7 10.9 2.8 6.6 8.7 2.6 8.2 6.1 4.9 16.5 3.2 8.2 4.9 1.6 0.2 0.0 0.3 0.2 0.0 0.3 0.4 0.3 0.4 0.5 0.0 0.2 0.0 0.0 0.4 1.1 0.1 0.0 0.2 0.7 0.6 0.4 0.3 0.2 0.3 0.0 0.3 0.6 POLR1A "DKFZP586M0122, FLJ21915, RPA1, RPO1-4" ENSG00000068654 "RNA polymerase I subunit A" O95602 2 86020216-86106155 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010145, HPA031513, HPA049700" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Intermediate filaments" "Nucleoli fibrillar center" "Nucleoplasm, Intermediate filaments" "CAB010145: AB_675814, HPA031513: , HPA049700: " "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "unprognostic (1.32e-1)" "unprognostic (1.93e-1)" "prognostic unfavourable (3.70e-9)" "unprognostic (1.06e-2)" "unprognostic (1.35e-1)" "prognostic unfavourable (3.37e-4)" "unprognostic (4.31e-2)" "unprognostic (4.56e-2)" "unprognostic (3.27e-1)" "unprognostic (2.20e-3)" "unprognostic (1.94e-1)" "prognostic unfavourable (8.41e-4)" "unprognostic (7.20e-2)" 14.3 12.9 10.1 12.4 16.5 9.7 10.3 12.2 20.3 11.1 11.0 17.4 8.3 9.4 19.5 7.4 13.5 12.3 11.7 12.7 9.0 9.2 11.5 15.1 9.4 9.6 9.0 9.4 12.6 14.3 18.2 15.9 11.4 13.8 10.7 11.8 13.9 11.2 12.5 22.5 12.3 8.6 16.0 8.0 11.2 10.4 14.9 10.9 14.0 10.3 11.4 14.2 10.9 9.6 2.6 2.6 1.8 2.5 2.0 3.8 1.2 9.3 21.3 9.5 18.3 9.3 7.5 13.8 8.6 5.7 12.4 7.7 26.7 7.4 21.5 9.2 8.8 10.9 24.5 12.7 11.1 8.9 12.6 18.5 9.1 17.9 6.6 17.5 10.0 5.7 8.0 18.4 14.4 9.6 24.5 5.4 8.5 8.3 12.9 7.5 17.3 14.1 15.6 20.9 10.0 5.5 15.4 14.8 7.7 9.5 12.6 6.8 7.4 6.1 15.2 15.1 11.9 12.8 17.3 7.7 7.4 18.8 7.8 15.1 13.3 1.8 1.5 0.2 3.0 2.5 3.8 2.0 1.5 2.5 1.8 2.6 1.4 1.8 0.7 2.0 1.9 2.6 0.7 1.2 10.1 16.5 12.2 20.3 9.0 9.2 9.0 9.4 13.8 10.9 POLR1B "FLJ10816, FLJ21921, RPA2, Rpo1-2" ENSG00000125630 "RNA polymerase I subunit B" Q9H9Y6 2 112541915-112577150 "Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037528 Supported Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA037528: AB_10671627" "unprognostic (1.66e-1)" "unprognostic (3.17e-2)" "unprognostic (2.55e-1)" "prognostic unfavourable (2.71e-5)" "unprognostic (2.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.98e-3)" "unprognostic (1.98e-1)" "unprognostic (2.05e-1)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.52e-4)" "unprognostic (6.12e-2)" "unprognostic (1.29e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (3.56e-2)" 8.8 11.0 6.4 10.6 6.8 4.9 15.7 8.0 8.2 7.6 7.0 7.7 8.6 5.8 9.3 7.4 12.8 9.2 9.2 6.1 5.7 6.1 11.3 20.5 8.0 11.3 6.8 3.7 11.3 25.2 20.7 11.5 7.2 5.2 7.7 8.5 7.3 10.0 8.3 14.7 9.2 8.0 7.9 4.8 11.4 8.1 15.7 5.0 9.6 15.7 11.5 14.6 8.9 11.8 9.4 11.0 2.5 6.3 10.2 17.1 7.3 9.4 9.9 6.3 13.0 6.8 6.6 11.8 7.1 5.4 12.0 10.5 22.2 5.6 22.7 10.6 4.7 13.3 26.4 14.5 13.9 10.2 13.3 13.1 9.9 16.7 7.2 20.9 9.1 6.2 10.5 12.5 19.3 9.3 23.7 8.2 6.3 8.3 9.4 13.6 30.6 19.7 14.2 10.4 24.1 8.3 9.0 15.9 14.8 6.5 16.5 9.0 7.6 7.4 8.4 7.4 10.9 6.8 10.4 11.1 18.3 19.6 5.6 13.4 6.2 0.2 6.0 2.5 8.3 6.3 17.1 9.4 8.4 8.9 11.0 9.3 10.3 10.4 0.4 10.2 4.8 2.6 11.3 7.3 6.4 6.8 8.0 8.2 5.7 6.1 6.8 3.7 5.2 5.0 POLR2A "POLR2, POLRA, RPB1" ENSG00000181222 "RNA polymerase II subunit A" P24928 17 7484366-7514616 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription" "DNA-binding, Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEK 293: 3.0;HL-60: 2.6;HMC-1: 3.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 4.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.9" "CAB012226, CAB016388, CAB022311" Enhanced Approved Nucleoplasm Nucleoplasm "CAB012226: AB_304749, CAB016388: AB_677353, CAB022311: " "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (1.58e-1)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (5.43e-2)" "unprognostic (8.77e-3)" "unprognostic (1.48e-1)" "unprognostic (5.19e-3)" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "unprognostic (3.70e-2)" "unprognostic (1.01e-3)" "unprognostic (1.25e-1)" "unprognostic (2.30e-2)" "unprognostic (1.49e-1)" "unprognostic (4.70e-2)" 5.0 5.9 4.5 5.7 7.4 26.4 8.5 5.8 7.8 7.2 4.3 4.8 4.5 4.3 5.5 5.4 7.0 4.6 4.2 4.5 6.0 3.5 4.6 4.4 6.4 11.5 4.7 4.2 5.2 5.8 5.4 4.8 4.2 5.4 4.3 4.9 6.3 5.5 8.1 6.6 6.6 6.0 4.5 6.1 6.2 5.3 13.2 2.9 15.0 5.6 4.1 5.0 5.3 4.6 0.7 0.7 4.9 1.0 0.0 1.2 0.0 0.3 0.0 0.3 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.4 0.1 0.5 0.0 0.2 0.0 0.2 0.4 3.0 0.7 1.2 0.2 0.0 2.6 3.9 0.4 0.0 0.3 0.0 0.2 0.3 0.0 0.5 0.0 0.1 0.8 0.4 0.9 1.1 0.0 0.0 0.0 1.4 0.3 0.9 1.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.5 0.8 0.4 0.2 0.4 0.0 0.6 0.3 3.0 0.5 0.6 1.2 0.4 0.3 0.3 0.5 0.4 0.1 0.7 0.6 0.5 4.9 0.0 1.0 0.7 0.5 0.0 4.5 7.4 5.8 7.8 6.0 3.5 4.7 4.2 5.4 2.9 POLR2B RPB2 ENSG00000047315 "RNA polymerase II subunit B" P30876 4 56977722-57031168 "Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037506 Supported Supported Nucleoplasm Nucleoplasm "HPA037506: AB_10672597" "unprognostic (9.88e-3)" "unprognostic (4.38e-2)" "unprognostic (1.83e-3)" "unprognostic (7.51e-2)" "unprognostic (2.30e-2)" "unprognostic (4.21e-3)" "unprognostic (1.24e-3)" "unprognostic (3.51e-1)" "unprognostic (6.39e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-1)" "unprognostic (1.95e-1)" "prognostic favourable (7.17e-4)" "unprognostic (1.91e-1)" "unprognostic (1.51e-1)" "unprognostic (3.43e-1)" "unprognostic (7.35e-2)" 24.5 34.3 31.1 34.6 31.0 21.4 24.8 43.8 33.3 25.9 26.0 18.8 24.9 22.5 35.1 21.4 27.4 28.3 21.2 32.9 29.3 21.7 26.2 21.4 21.2 32.4 28.0 30.2 26.4 28.1 40.7 37.3 25.4 28.3 24.8 26.5 18.4 30.5 28.2 61.8 24.4 27.3 27.6 26.4 27.1 28.8 26.6 26.8 33.4 27.0 34.7 35.1 31.5 22.4 19.8 15.2 27.8 13.9 18.0 23.8 12.7 24.7 20.7 37.4 31.6 30.9 27.9 20.0 33.0 33.6 33.1 31.0 26.3 25.0 38.6 31.3 30.5 17.6 44.9 25.1 47.4 18.3 20.1 29.0 23.1 22.9 35.8 49.9 33.6 30.0 25.3 37.8 23.1 39.4 43.1 33.0 38.1 18.1 47.0 19.3 30.8 24.3 34.3 24.6 21.2 22.6 28.2 31.2 35.0 20.5 39.1 28.4 21.0 27.8 28.7 24.1 32.4 25.2 43.3 26.6 25.3 56.3 27.5 27.0 29.8 27.8 12.2 16.8 20.7 12.4 22.0 19.8 20.3 21.4 15.2 14.4 19.9 23.8 11.3 18.0 13.9 12.9 20.9 12.7 31.1 31.0 43.8 33.3 29.3 21.7 28.0 30.2 28.3 26.8 POLR3A "hRPC155, RPC1, RPC155" ENSG00000148606 "RNA polymerase III subunit A" O14802 10 77969251-78029545 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037926 Uncertain Supported Nucleoplasm Nucleoplasm "HPA037926: AB_10672400" "unprognostic (6.83e-2)" "unprognostic (3.41e-2)" "unprognostic (4.54e-2)" "unprognostic (2.76e-2)" "unprognostic (6.41e-2)" "unprognostic (1.75e-1)" "prognostic unfavourable (3.64e-6)" "unprognostic (3.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (6.64e-2)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (1.34e-1)" "unprognostic (3.19e-1)" "unprognostic (1.30e-1)" "unprognostic (4.11e-2)" 7.1 10.2 10.3 8.3 21.7 5.9 10.6 22.2 29.7 9.2 8.1 12.8 7.4 8.6 9.4 13.3 8.6 8.5 7.4 7.4 9.4 9.6 9.3 9.3 6.8 8.7 8.1 11.0 11.5 10.7 13.8 17.3 10.1 20.4 10.2 10.7 10.4 8.6 8.2 17.6 11.2 7.8 9.7 6.6 8.9 8.2 11.7 9.8 12.6 9.6 4.4 13.4 7.9 8.0 7.5 5.4 8.0 6.4 6.5 8.8 3.6 7.3 8.8 9.3 15.4 6.1 7.9 6.2 8.4 11.0 10.9 10.8 11.5 5.3 9.1 5.2 7.3 8.6 16.1 9.2 13.3 6.7 11.8 7.3 7.0 14.2 5.8 12.5 6.2 6.7 6.6 19.3 18.0 9.5 13.6 5.7 10.5 5.4 9.4 8.0 10.1 40.0 9.0 5.9 5.9 5.4 4.8 8.5 10.8 8.1 15.1 8.6 11.2 6.6 10.4 7.0 6.8 7.6 16.6 8.9 9.3 11.1 12.5 13.2 3.4 8.0 5.2 2.9 7.8 6.4 7.6 5.6 6.0 7.2 4.8 7.5 5.7 6.6 3.3 6.5 5.4 5.4 8.8 3.6 10.3 21.7 22.2 29.7 9.4 9.6 8.1 11.0 20.4 9.8 POLR3B "FLJ10388, RPC2" ENSG00000013503 "RNA polymerase III subunit B" Q9NW08 12 106357658-106510198 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036466 Supported Approved "Nuclear speckles" "Nuclear speckles" "HPA036466: AB_10671842" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (4.80e-2)" "unprognostic (1.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-1)" "unprognostic (4.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.33e-1)" "unprognostic (3.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.09e-2)" "prognostic favourable (1.21e-4)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" 6.4 14.0 7.1 7.9 14.6 6.5 6.9 8.6 13.6 8.6 7.2 8.2 5.7 6.0 10.1 7.2 14.8 7.7 5.8 8.2 8.9 7.1 9.9 17.5 7.1 11.4 6.2 10.4 11.3 11.9 22.5 17.0 22.9 12.3 8.0 8.3 6.2 8.6 9.9 12.1 15.3 5.7 7.8 6.0 6.4 7.5 9.9 4.7 10.3 8.5 10.2 10.0 7.3 10.1 4.3 4.9 9.8 4.1 3.7 6.3 3.1 11.1 5.3 11.8 5.6 10.5 9.6 16.4 15.7 9.5 10.9 8.5 9.7 3.1 14.2 5.6 9.7 10.4 13.6 13.4 13.6 11.5 9.1 11.3 7.1 8.2 6.7 17.9 12.3 8.5 9.6 10.9 12.7 8.1 16.6 4.7 8.3 8.2 13.0 6.0 12.7 19.9 7.9 7.0 9.3 6.2 15.2 12.8 7.0 9.6 12.9 9.2 12.0 5.3 7.7 6.0 7.1 9.7 9.0 5.8 14.8 21.2 2.9 11.1 6.4 9.8 3.9 2.6 4.1 4.1 5.5 4.3 4.5 4.3 4.9 2.6 6.3 3.9 2.6 3.7 4.0 1.8 4.7 3.1 7.1 14.6 8.6 13.6 8.9 7.1 6.2 10.4 12.3 4.7 POLRMT "APOLMT, h-mtRPOL, MTRNAP, MTRPOL" ENSG00000099821 "RNA polymerase mitochondrial" O00411 19 617224-633604 "Enzymes, Predicted intracellular proteins" Transcription "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006366 Uncertain Supported Mitochondria Mitochondria "HPA006366: AB_1079654" "unprognostic (3.24e-1)" "unprognostic (4.31e-2)" "unprognostic (7.96e-2)" "prognostic favourable (4.50e-4)" "unprognostic (9.46e-2)" "unprognostic (2.94e-2)" "unprognostic (3.04e-2)" "unprognostic (9.41e-2)" "unprognostic (1.45e-1)" "unprognostic (3.48e-1)" "unprognostic (7.64e-3)" "unprognostic (1.81e-2)" "unprognostic (1.62e-1)" "unprognostic (1.28e-3)" "unprognostic (1.66e-1)" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" 10.2 10.7 10.1 16.3 11.9 6.9 8.1 12.1 20.7 9.5 11.6 12.3 4.4 16.7 9.8 12.2 14.4 8.7 12.7 24.7 11.5 8.9 12.9 21.4 7.3 11.8 9.4 15.1 10.1 15.9 9.5 10.7 6.2 9.7 10.2 8.8 8.5 9.6 11.7 42.2 16.7 12.8 10.8 8.4 12.8 11.2 32.1 6.3 11.6 11.1 8.6 10.4 10.1 7.8 8.2 7.3 3.1 5.5 7.5 9.0 5.3 10.4 19.0 4.3 19.1 9.1 5.2 16.0 4.9 5.8 7.3 6.7 19.1 7.2 10.8 10.0 4.5 10.9 16.1 9.4 5.4 12.1 38.3 8.4 11.8 24.5 9.5 14.1 16.0 5.0 13.3 7.4 9.1 10.3 15.7 10.8 6.7 14.8 18.7 19.4 17.3 13.4 18.1 6.0 18.4 9.7 9.0 14.0 9.9 4.4 12.2 12.2 6.9 12.9 6.1 7.9 10.2 12.4 14.4 25.8 21.2 16.5 17.0 11.8 9.7 0.0 3.7 3.1 9.0 5.2 7.1 7.8 6.7 6.6 7.3 8.2 5.7 6.3 0.6 7.5 5.5 7.2 4.1 5.3 10.1 11.9 12.1 20.7 11.5 8.9 9.4 15.1 9.7 6.3 POMGNT2 "AGO61, C3orf39, FLJ14566, GTDC2" ENSG00000144647 "Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)" Q8NAT1 3 43079232-43106076 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034870, HPA040989" Uncertain "Intracellular and membrane" "HPA034870: AB_10602701, HPA040989: " "unprognostic (2.37e-3)" "unprognostic (8.22e-2)" "prognostic favourable (8.13e-5)" "unprognostic (2.57e-2)" "unprognostic (4.17e-2)" "unprognostic (1.96e-1)" "prognostic unfavourable (1.26e-5)" "unprognostic (8.71e-2)" "unprognostic (1.73e-2)" "unprognostic (7.43e-2)" "unprognostic (1.95e-2)" "unprognostic (4.01e-1)" "prognostic favourable (4.00e-7)" "unprognostic (4.98e-2)" "unprognostic (1.55e-1)" "unprognostic (3.26e-1)" "unprognostic (2.57e-1)" 8.4 12.7 13.9 4.1 20.2 16.6 6.8 28.4 32.7 14.2 7.1 13.1 6.2 3.8 28.2 12.0 7.9 21.7 10.3 15.6 12.5 13.2 7.8 6.8 7.3 2.9 10.6 12.3 21.1 14.7 14.0 10.6 5.6 13.5 10.6 3.2 11.1 13.5 15.8 15.0 7.2 4.1 20.1 7.3 4.4 7.4 9.1 8.8 4.4 10.6 3.4 3.4 7.6 7.6 2.9 1.2 1.0 0.9 1.6 5.7 1.8 11.4 8.8 5.1 15.5 19.7 5.1 8.1 3.3 6.0 11.8 13.9 10.6 8.1 0.0 12.5 6.0 0.2 8.3 9.6 5.2 0.0 23.3 8.1 7.0 10.1 7.5 5.6 9.7 5.9 7.1 7.9 4.7 4.5 6.6 0.0 4.6 6.8 10.2 1.5 11.2 16.5 4.0 3.6 7.2 6.9 8.4 8.1 7.4 6.9 5.6 6.3 10.7 5.0 2.1 9.6 13.5 14.0 13.5 8.7 13.0 0.1 12.3 11.4 10.1 0.0 0.9 1.0 5.7 0.8 5.1 2.9 3.8 3.8 1.1 1.9 4.9 3.8 0.0 1.6 0.8 1.2 2.9 1.8 13.9 20.2 28.4 32.7 12.5 13.2 10.6 12.3 13.5 8.8 POMK "FLJ23356, SgK196" ENSG00000185900 "Protein-O-mannose kinase" Q9H5K3 8 43093506-43123434 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013321 Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA013321: AB_2668809" "unprognostic (1.66e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-1)" "unprognostic (4.37e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.56e-2)" "unprognostic (2.42e-1)" "unprognostic (2.50e-1)" "unprognostic (8.10e-2)" "unprognostic (1.23e-3)" "unprognostic (1.03e-1)" "unprognostic (2.32e-1)" "unprognostic (7.09e-2)" "unprognostic (1.06e-1)" "unprognostic (3.71e-3)" "unprognostic (2.10e-2)" 4.7 5.5 9.8 5.6 14.3 12.5 5.1 12.3 18.6 6.9 4.8 8.3 2.2 4.5 6.9 4.4 7.1 6.2 4.8 3.8 7.7 7.0 3.4 4.5 5.5 6.0 4.8 11.1 5.8 9.3 6.3 7.4 6.1 10.5 5.6 5.9 6.1 6.8 4.0 6.2 7.1 5.6 6.4 6.7 7.6 6.8 7.1 7.2 7.5 7.4 3.2 7.4 4.6 5.0 2.6 2.6 6.7 2.9 1.0 3.3 1.3 3.5 7.5 5.8 15.1 2.8 3.4 5.5 2.1 3.1 5.5 4.0 5.5 9.1 4.9 4.6 3.8 5.8 8.2 6.3 5.3 1.9 1.4 13.9 5.5 2.4 2.0 4.7 7.8 3.8 2.7 7.3 5.3 5.4 3.2 14.8 3.7 1.6 9.9 2.0 11.8 1.0 6.8 6.8 2.8 1.5 9.8 5.6 4.1 9.1 3.1 3.0 9.7 3.2 7.4 8.4 8.4 8.6 4.2 4.8 8.5 9.3 3.5 3.2 9.9 0.8 2.9 1.9 2.3 2.4 3.3 1.8 1.3 1.3 2.6 2.6 1.8 2.3 6.7 1.0 1.5 2.5 1.1 1.3 9.8 14.3 12.3 18.6 7.7 7.0 4.8 11.1 10.5 7.2 POMT1 LGMD2K ENSG00000130714 "Protein O-mannosyltransferase 1" Q9Y6A1 9 131502902-131523806 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065252 Approved "Golgi apparatus" "Golgi apparatus" "HPA065252: " "unprognostic (2.00e-3)" "unprognostic (2.02e-1)" "unprognostic (1.60e-1)" "unprognostic (5.09e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (5.35e-3)" "unprognostic (1.14e-1)" "unprognostic (9.76e-3)" "unprognostic (2.84e-1)" "prognostic favourable (3.90e-5)" "unprognostic (8.36e-2)" "prognostic favourable (4.68e-5)" "unprognostic (2.41e-2)" "unprognostic (1.61e-1)" "unprognostic (4.72e-2)" "unprognostic (2.12e-1)" 9.5 12.3 21.6 10.6 18.8 10.2 10.2 34.2 22.4 10.0 12.1 16.9 14.6 11.2 15.0 14.6 8.8 14.6 13.0 15.2 25.8 17.9 13.8 12.8 10.6 13.2 15.0 16.5 17.2 16.9 17.1 18.0 12.9 15.2 16.0 11.6 13.3 19.5 17.1 28.2 16.6 11.9 12.1 13.4 12.3 10.7 49.9 13.4 8.7 11.6 5.5 11.0 7.8 9.5 2.8 5.1 3.4 3.8 3.8 10.8 4.9 6.7 10.7 9.8 16.4 12.6 10.2 17.7 7.8 9.6 12.4 8.5 11.2 9.4 2.1 9.4 17.9 15.1 11.9 8.4 6.5 11.0 17.1 3.8 25.3 7.8 14.9 9.9 8.6 7.1 7.6 8.2 2.8 10.7 6.8 11.4 12.4 17.9 9.3 22.6 5.6 13.5 10.8 9.2 16.0 10.9 2.0 11.0 9.8 13.2 15.3 7.7 22.5 10.0 11.6 9.8 2.1 17.7 6.5 7.1 6.2 3.5 5.8 18.6 8.0 0.0 3.8 3.4 7.4 3.6 10.8 2.8 7.2 7.4 5.1 2.7 6.7 5.5 0.5 3.8 3.3 3.1 7.6 4.9 21.6 18.8 34.2 22.4 25.8 17.9 15.0 16.5 15.2 13.4 POMT2 LGMD2N ENSG00000009830 "Protein O-mannosyltransferase 2" Q9UKY4 14 77274956-77320884 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003663 Uncertain "HPA003663: AB_1079655" "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (2.40e-4)" "unprognostic (7.10e-3)" "unprognostic (1.17e-1)" "unprognostic (1.68e-1)" "unprognostic (6.89e-3)" "unprognostic (1.94e-3)" "unprognostic (8.50e-3)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.75e-3)" "unprognostic (3.46e-2)" 6.7 10.8 10.4 6.8 11.4 3.8 7.7 12.5 13.3 6.8 6.3 18.0 9.8 4.6 6.9 17.1 5.7 8.7 6.9 7.7 9.3 7.7 8.1 8.3 6.2 3.0 11.7 6.2 7.6 10.6 14.7 16.1 11.4 9.7 7.3 5.8 8.2 10.1 12.3 17.0 4.3 4.6 7.8 8.4 5.2 5.6 30.9 14.4 2.5 11.5 4.9 3.8 5.7 5.0 1.4 1.9 0.8 1.9 0.0 1.7 0.4 10.6 13.6 13.3 15.0 9.5 7.6 10.6 9.4 7.7 14.0 12.0 6.7 9.6 3.1 7.6 8.8 11.9 6.2 9.4 9.8 4.7 8.5 1.9 6.8 5.5 11.6 2.1 6.4 7.7 10.0 13.1 12.9 8.1 5.0 7.5 9.2 21.0 3.6 10.3 3.7 11.6 3.6 12.9 2.9 14.6 7.8 11.2 11.0 6.1 10.4 7.8 10.7 4.5 6.7 10.6 16.8 12.2 8.2 4.9 9.6 1.4 5.4 3.3 9.3 0.0 0.4 0.0 1.7 1.9 0.4 1.4 0.0 0.3 0.9 0.2 0.1 0.0 0.8 0.0 0.8 1.9 0.0 0.4 10.4 11.4 12.5 13.3 9.3 7.7 11.7 6.2 9.7 14.4 PON1 "ESA, PON" ENSG00000005421 "Paraoxonase 1" P27169 7 95297676-95324707 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "liver: 144.1" "Cell line enhanced" "Detected in some" "A549: 1.4;RH-30: 1.0" "Cancer enriched" "Detected in some" 78 "liver cancer: 97.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001610 Approved "Secreted to blood" 96000000000 24000000000 "HPA001610: AB_1079656" "unprognostic (2.02e-2)" "unprognostic (2.41e-2)" "unprognostic (3.04e-1)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "prognostic favourable (7.24e-7)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (9.02e-3)" "unprognostic (1.76e-3)" "unprognostic (3.97e-2)" "unprognostic (6.74e-9)" "unprognostic (1.09e-3)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (5.54e-3)" 0.0 1.7 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 144.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 0.0 1.0 0.1 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.4 0.2 0.0 1.0 0.0 0.0 0.3 0.6 0.1 0.0 0.3 0.0 0.4 0.0 0.5 0.0 0.1 0.0 0.2 0.9 0.3 0.0 0.0 0.2 0.2 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.0 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 PON2 ENSG00000105854 "Paraoxonase 2" Q15165 7 95404863-95435329 "Candidate cardiovascular disease genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 81.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "myeloid DC: 22.1" "Lineage enriched" "Detected in many" 4 "dendritic cells: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025430, HPA029193" Enhanced "Secreted to blood" 350000000 "CAB025430: , HPA029193: AB_10602148" "unprognostic (1.43e-1)" "prognostic unfavourable (1.43e-5)" "unprognostic (3.80e-1)" "unprognostic (4.14e-1)" "unprognostic (3.89e-2)" "unprognostic (3.77e-3)" "unprognostic (1.19e-3)" "unprognostic (9.87e-3)" "unprognostic (9.54e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.80e-1)" "prognostic unfavourable (4.30e-8)" "unprognostic (1.40e-1)" "unprognostic (6.43e-2)" "unprognostic (7.99e-3)" "unprognostic (2.56e-1)" 17.0 42.2 54.1 7.5 59.1 3.3 23.1 25.4 52.2 16.5 24.0 29.7 7.4 28.2 16.6 22.7 10.2 15.0 18.9 13.1 57.2 31.4 23.9 81.0 33.1 4.5 41.4 31.0 10.6 7.2 10.9 15.0 34.3 34.8 14.7 31.1 9.9 8.5 17.2 4.3 19.4 19.1 18.4 44.2 7.3 8.8 9.6 40.1 1.8 13.6 5.1 11.2 13.7 8.1 0.9 22.1 0.5 5.2 5.0 3.5 3.0 9.6 60.4 49.1 26.6 6.9 15.2 13.8 19.7 23.1 15.4 16.8 13.6 22.0 0.0 27.6 19.4 6.5 8.9 15.1 17.5 0.1 11.7 4.9 36.3 45.0 10.9 0.0 6.8 22.0 17.5 8.2 11.3 31.7 3.1 0.2 45.2 8.8 0.0 5.4 9.6 14.0 0.0 23.2 2.3 47.5 7.5 3.4 10.6 28.1 31.4 18.9 9.2 3.1 34.5 23.1 16.8 7.7 18.9 5.2 6.0 0.0 21.6 4.5 30.1 0.0 5.2 0.5 3.5 2.6 3.1 0.9 1.3 3.2 22.1 0.4 1.9 2.4 0.0 5.0 1.2 5.3 0.6 3.0 54.1 59.1 25.4 34.3 57.2 31.4 41.4 31.0 34.8 40.1 PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359944-95396368 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 148.0" "Cell line enhanced" "Detected in some" "A549: 19.8;CACO-2: 6.4;CAPAN-2: 4.8;Hep G2: 21.9;T-47d: 12.3" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 12 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 12 "NK-cells: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014848, CAB025250" Enhanced "Secreted to blood" 1756666667 350000000 "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" 0.4 0.7 0.3 0.1 0.6 0.0 6.9 0.2 0.5 0.9 1.0 0.3 2.3 1.5 0.2 1.2 0.2 0.4 0.7 0.4 0.7 0.3 0.7 148.0 4.0 0.0 0.4 0.2 2.4 7.1 0.0 15.5 0.2 0.5 0.2 0.4 0.8 21.4 5.5 0.1 1.8 1.7 0.1 0.3 0.2 0.5 3.6 0.4 0.4 1.5 0.0 1.1 0.5 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 2.1 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 4.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 12.3 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.6 0.2 0.5 0.7 0.3 0.4 0.2 0.5 0.4 POP1 ENSG00000104356 "POP1 homolog, ribonuclease P/MRP subunit" Q99575 8 98117297-98159834 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066194 Supported Nucleoli Nucleoli "HPA066194: " "prognostic unfavourable (2.54e-4)" "unprognostic (9.42e-2)" "unprognostic (5.96e-3)" "unprognostic (3.31e-2)" "unprognostic (1.46e-1)" "unprognostic (7.46e-2)" "prognostic unfavourable (1.26e-6)" "prognostic unfavourable (9.88e-4)" "unprognostic (4.85e-1)" "unprognostic (1.47e-1)" "unprognostic (3.79e-1)" "unprognostic (1.39e-2)" "prognostic unfavourable (5.97e-4)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (2.96e-1)" 6.1 5.5 7.8 9.0 9.7 3.7 5.8 14.3 10.2 4.3 5.4 5.2 2.7 4.3 6.0 4.2 9.1 6.6 3.9 5.0 5.7 4.7 10.5 6.4 5.2 9.1 4.1 7.6 8.4 5.8 7.6 11.1 3.5 7.4 5.0 13.8 6.2 5.1 4.2 5.7 8.2 5.1 5.2 4.0 8.8 5.7 11.8 6.2 8.8 5.0 5.6 11.3 4.3 5.0 10.5 7.7 10.9 7.4 4.1 9.8 2.5 12.6 7.6 8.3 7.7 2.9 2.1 5.5 10.9 9.2 11.4 8.5 7.8 8.2 8.9 15.7 7.9 8.5 24.2 10.8 12.3 6.4 10.2 17.8 6.1 5.3 1.3 9.4 11.2 1.7 2.0 12.6 5.0 8.8 9.7 8.1 10.6 10.1 13.6 4.8 6.3 10.6 11.3 4.9 6.4 8.3 6.8 20.0 4.7 5.0 8.5 3.8 11.6 3.5 12.0 10.0 7.2 12.6 21.5 8.1 7.6 19.2 7.8 10.2 8.7 10.9 6.7 4.6 9.8 7.4 7.8 6.2 7.1 6.5 6.2 10.5 9.3 8.6 0.9 4.1 3.4 7.7 5.9 2.5 7.8 9.7 14.3 10.2 5.7 4.7 4.1 7.6 7.4 6.2 POP4 RPP29 ENSG00000105171 "POP4 homolog, ribonuclease P/MRP subunit" O95707 19 29604017-29617237 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042748 Approved "HPA042748: AB_10964774" "unprognostic (5.88e-2)" "unprognostic (2.78e-2)" "unprognostic (7.21e-2)" "unprognostic (4.00e-3)" "unprognostic (4.50e-2)" "unprognostic (5.73e-2)" "prognostic unfavourable (3.31e-4)" "unprognostic (8.35e-2)" "unprognostic (2.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.20e-2)" "unprognostic (9.47e-2)" "unprognostic (5.84e-2)" "unprognostic (4.21e-1)" "unprognostic (1.77e-2)" "unprognostic (5.23e-3)" "unprognostic (8.08e-3)" 23.7 17.1 14.6 14.5 15.8 13.6 11.1 14.1 18.9 8.9 19.4 14.0 10.5 13.8 15.5 11.8 15.1 12.1 9.5 17.7 13.8 12.8 21.0 22.9 10.4 12.7 14.7 14.4 11.0 15.7 10.6 10.0 15.2 14.7 12.8 7.7 13.6 17.3 10.6 29.1 12.2 17.1 11.0 15.1 15.7 15.3 17.2 8.0 17.8 18.0 16.2 16.3 11.6 10.0 28.9 27.0 35.3 34.2 23.3 35.2 26.9 16.9 30.1 2.9 2.4 3.9 2.1 11.5 16.1 2.1 4.9 5.0 13.4 4.3 14.6 28.3 3.3 8.0 4.5 5.2 1.9 32.4 27.9 17.0 9.7 8.3 4.2 19.5 9.0 2.3 3.4 3.7 2.0 3.9 14.8 4.2 3.7 17.8 11.6 3.8 4.8 16.0 7.8 20.0 7.4 2.6 7.8 7.0 6.9 16.7 7.7 8.0 6.8 5.7 11.5 6.2 18.5 9.4 14.1 13.9 26.0 18.0 7.3 10.8 5.7 35.3 27.0 26.4 26.7 34.2 19.0 28.9 25.5 28.4 27.0 23.6 20.9 25.3 16.4 23.3 26.7 22.0 35.2 26.9 14.6 15.8 14.1 18.9 13.8 12.8 14.7 14.4 14.7 8.0 POP5 ENSG00000167272 "POP5 homolog, ribonuclease P/MRP subunit" Q969H6 12 120578764-120581398 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047598, HPA069204" Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA047598: , HPA069204: " "unprognostic (1.50e-2)" "prognostic favourable (2.68e-5)" "unprognostic (1.55e-1)" "unprognostic (3.61e-3)" "unprognostic (3.81e-1)" "unprognostic (1.50e-1)" "unprognostic (4.80e-3)" "unprognostic (1.28e-1)" "unprognostic (7.34e-2)" "unprognostic (5.75e-2)" "unprognostic (4.13e-2)" "unprognostic (1.33e-1)" "prognostic unfavourable (4.85e-4)" "unprognostic (3.07e-1)" "unprognostic (6.21e-2)" "unprognostic (2.68e-1)" "unprognostic (5.68e-2)" 16.3 33.8 16.2 25.6 14.4 14.1 23.9 8.7 16.7 18.6 17.5 13.6 24.2 11.8 14.5 27.1 15.9 14.6 19.5 25.8 18.1 13.9 24.1 24.1 18.3 19.7 16.9 15.9 11.7 18.9 25.0 17.5 8.2 14.2 15.6 18.0 15.1 20.9 22.6 13.3 12.7 15.1 19.5 14.4 20.3 15.2 9.0 12.1 24.2 19.8 18.9 19.6 13.7 19.2 32.0 33.5 3.6 19.7 18.2 28.2 22.8 20.1 34.5 12.3 15.0 23.3 12.6 19.5 17.0 11.0 20.7 15.9 29.7 9.3 11.8 25.8 13.6 21.4 20.5 32.3 18.6 28.0 31.1 14.4 22.5 33.6 16.4 20.4 15.2 15.8 18.6 23.9 11.0 17.3 17.6 7.6 20.6 44.3 16.5 18.4 14.6 29.8 19.5 15.0 32.4 29.0 20.7 9.6 10.5 28.7 8.4 21.8 39.3 19.6 12.4 10.8 16.3 17.3 18.5 19.9 33.4 20.9 21.1 24.9 17.3 3.6 16.2 3.5 24.7 19.7 22.6 32.0 22.6 23.0 19.0 22.4 28.2 26.8 1.1 18.2 16.7 33.5 21.4 22.8 16.2 14.4 8.7 16.7 18.1 13.9 16.9 15.9 14.2 12.1 POP7 "RPP2, RPP20" ENSG00000172336 "POP7 homolog, ribonuclease P/MRP subunit" O75817 7 100706053-100707495 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021007 Uncertain Supported Nucleoli,Vesicles "Nucleoli, Vesicles" "HPA021007: AB_10963575" "unprognostic (3.19e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-1)" "prognostic unfavourable (4.99e-5)" "unprognostic (2.98e-2)" "unprognostic (2.28e-1)" "unprognostic (3.12e-2)" "unprognostic (9.50e-2)" "unprognostic (3.88e-1)" "prognostic unfavourable (6.02e-4)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (6.21e-2)" "unprognostic (6.73e-2)" 12.3 16.6 20.5 15.1 21.0 25.3 16.1 25.1 33.2 11.3 14.7 8.7 14.0 17.5 13.9 12.5 20.4 13.4 13.9 19.6 18.3 18.1 13.1 31.4 11.7 18.2 16.8 22.0 13.2 21.2 6.6 11.5 18.1 13.3 16.0 8.1 10.0 24.2 15.8 46.4 22.6 17.6 12.3 12.9 12.3 15.5 7.0 9.4 11.0 11.6 20.5 11.8 11.5 12.5 32.1 30.4 46.4 35.6 42.1 37.0 32.0 24.3 24.2 9.8 17.3 5.2 5.0 19.2 13.8 6.5 15.3 15.2 35.4 15.8 19.8 23.3 6.0 15.5 14.3 16.2 7.6 17.9 43.2 8.9 15.8 34.0 8.8 13.6 10.9 5.8 6.1 15.7 15.5 8.5 31.5 17.7 8.0 69.0 34.1 46.7 30.1 33.5 25.8 10.4 33.5 9.1 13.4 19.7 20.0 11.1 34.4 16.3 11.3 13.8 8.3 21.3 25.6 41.8 27.1 7.5 20.4 35.4 13.4 23.5 23.1 46.4 35.6 38.2 32.4 34.1 29.4 32.1 32.5 31.6 30.4 26.4 29.9 31.1 21.9 42.1 35.3 27.9 37.0 32.0 20.5 21.0 25.1 33.2 18.3 18.1 16.8 22.0 13.3 9.4 POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 78.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Vesicles" Cytosol "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavourable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" 12.8 48.2 7.4 7.5 10.8 3.6 15.0 5.3 16.4 11.0 20.8 9.6 32.1 24.9 9.0 8.2 13.4 12.8 9.9 8.4 7.1 7.2 12.0 78.4 13.7 9.9 5.2 10.1 14.4 12.8 12.1 18.5 18.6 7.1 9.3 5.3 10.8 7.8 58.7 13.1 10.0 24.3 7.0 5.2 11.7 9.8 22.4 5.0 8.2 33.3 9.9 8.6 9.8 10.2 5.7 20.6 26.7 18.4 11.2 9.9 13.9 12.7 27.9 12.8 23.7 48.5 18.4 21.4 5.3 17.5 10.1 14.1 20.9 56.7 12.2 4.9 11.6 6.2 16.8 8.4 4.3 10.4 12.4 5.6 8.2 38.7 33.7 5.6 10.1 37.8 10.6 13.3 9.7 9.4 16.9 5.3 9.1 18.7 6.1 10.1 15.9 15.8 8.7 8.4 13.1 11.4 15.4 13.4 12.8 14.4 73.3 19.3 21.0 9.6 8.4 9.5 10.5 14.3 10.5 5.2 8.0 8.3 13.4 8.6 12.2 26.7 18.4 25.3 9.9 17.7 8.3 5.4 8.4 9.2 20.6 5.7 8.4 7.1 24.3 11.2 13.0 5.8 8.7 13.9 7.4 10.8 5.3 16.4 7.1 7.2 5.2 10.1 7.1 5.0 PPA1 "IOPPP, PP, PP1, Ppase, SID6-8061" ENSG00000180817 "Pyrophosphatase (inorganic) 1" Q15181 10 70202830-70233911 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019878, HPA020096" Supported Supported Vesicles 110000 Vesicles "HPA019878: AB_1855601, HPA020096: AB_1855600" "unprognostic (1.50e-1)" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.42e-1)" "unprognostic (4.47e-2)" "unprognostic (2.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-1)" "unprognostic (2.13e-2)" "unprognostic (3.60e-2)" "unprognostic (1.82e-3)" "unprognostic (5.36e-2)" "unprognostic (2.37e-1)" "unprognostic (3.53e-2)" "unprognostic (2.74e-1)" 46.6 55.5 41.3 36.8 56.0 24.2 88.7 66.8 62.2 34.8 45.7 25.2 43.7 33.2 30.4 59.6 48.6 38.1 31.5 30.0 46.7 54.2 40.7 59.0 39.1 54.6 74.3 47.5 17.9 72.6 23.3 29.5 34.6 60.7 24.4 53.4 26.1 36.8 42.1 37.0 24.6 41.0 32.8 72.7 22.4 32.5 25.1 47.2 20.4 52.0 35.8 44.4 32.7 40.2 21.5 48.9 1.0 17.7 15.5 35.6 25.3 58.1 24.1 21.6 63.6 58.8 51.9 20.2 21.8 41.0 34.2 36.1 73.4 30.9 84.3 19.9 21.7 47.1 63.2 42.5 35.0 79.2 60.1 23.0 24.4 41.9 37.1 56.6 14.6 34.0 50.9 27.4 73.1 41.3 53.6 45.4 32.2 34.1 54.7 53.2 22.5 66.9 33.5 24.7 49.3 71.3 36.6 64.9 21.8 24.0 94.1 18.6 23.5 25.5 18.7 9.5 36.2 31.2 41.3 15.0 32.8 61.7 14.7 79.5 8.3 0.0 17.7 0.4 13.3 13.8 35.6 21.5 30.8 23.1 48.9 13.8 34.2 28.9 1.0 15.5 14.5 11.3 30.1 25.3 41.3 56.0 66.8 62.2 46.7 54.2 74.3 47.5 60.7 47.2 PPA2 FLJ20459 ENSG00000138777 "Pyrophosphatase (inorganic) 2" Q9H2U2 4 105369077-105474081 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Approved Nucleoplasm,Mitochondria 8300 Mitochondria Nucleoplasm "HPA030888: , HPA031671: AB_10603986, HPA031672: AB_2673988" "prognostic unfavourable (2.98e-4)" "unprognostic (5.64e-2)" "prognostic favourable (6.60e-4)" "unprognostic (9.26e-3)" "unprognostic (2.93e-2)" "unprognostic (5.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "unprognostic (9.54e-2)" "prognostic favourable (1.27e-11)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" 9.2 18.0 18.4 17.2 15.4 24.0 20.6 12.3 17.6 10.2 19.8 9.3 20.3 18.1 13.3 20.7 14.8 10.7 18.7 42.5 15.6 15.3 23.7 21.2 23.1 34.8 17.2 12.1 9.5 25.0 10.4 15.0 9.3 15.4 16.1 16.7 12.6 21.4 26.8 29.6 15.0 16.8 22.8 12.4 12.1 15.0 9.7 10.7 9.4 14.3 28.2 10.6 12.2 9.5 20.0 35.3 14.7 20.8 22.0 17.0 14.6 11.5 5.5 10.7 18.1 6.8 5.5 7.8 6.5 8.6 8.0 5.7 12.1 17.0 9.5 8.7 5.3 5.8 21.4 10.3 9.5 13.4 7.6 8.5 8.9 11.0 5.4 20.1 8.2 5.3 10.7 5.5 4.3 7.7 14.1 13.1 7.3 14.6 17.1 14.5 7.8 18.7 15.2 6.6 9.3 26.5 8.9 11.0 6.6 4.5 26.7 9.4 14.0 16.4 4.1 5.8 11.3 6.2 11.3 11.6 14.6 9.9 10.1 10.9 7.8 14.7 15.0 9.7 15.3 20.8 13.3 20.0 16.0 16.2 35.3 16.6 15.5 17.0 6.4 22.0 16.2 17.7 15.9 14.6 18.4 15.4 12.3 17.6 15.6 15.3 17.2 12.1 15.4 10.7 PPAT "GPAT, PRAT" ENSG00000128059 "Phosphoribosyl pyrophosphate amidotransferase" Q06203 4 56393362-56435615 "Enzymes, Predicted intracellular proteins" "Purine biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036091, HPA036092" Approved Approved "Midbody ring" "Midbody ring" "HPA036091: , HPA036092: AB_10603132" "unprognostic (5.11e-2)" "unprognostic (5.13e-2)" "unprognostic (1.39e-2)" "prognostic unfavourable (5.15e-5)" "unprognostic (1.38e-1)" "unprognostic (4.37e-3)" "prognostic unfavourable (1.14e-8)" "unprognostic (6.74e-3)" "unprognostic (2.95e-2)" "unprognostic (3.79e-2)" "unprognostic (2.88e-3)" "unprognostic (1.51e-1)" "prognostic unfavourable (8.34e-4)" "unprognostic (1.41e-1)" "unprognostic (3.01e-1)" "prognostic unfavourable (1.95e-4)" "unprognostic (1.09e-1)" 5.6 10.1 10.8 9.5 11.7 7.3 11.1 11.7 13.7 7.3 6.0 6.9 7.6 6.1 7.4 5.6 8.1 7.1 5.3 4.4 8.9 9.7 9.7 10.3 3.9 12.0 9.7 12.1 12.5 10.8 5.6 6.8 10.3 9.5 6.2 7.7 3.8 9.2 7.6 7.0 6.7 5.1 5.6 9.7 6.3 5.5 13.0 8.9 15.2 9.4 6.4 12.0 7.0 6.6 8.2 3.7 3.3 3.9 11.2 9.5 4.3 8.6 7.2 14.9 7.2 4.8 6.3 12.1 9.6 4.3 8.0 8.5 14.4 10.6 30.4 13.2 4.5 6.4 28.6 9.7 16.1 7.9 12.7 12.2 9.1 15.9 7.4 24.1 7.7 5.4 7.6 11.4 12.8 8.4 30.8 16.8 9.0 7.8 29.7 18.3 19.7 8.6 25.2 9.7 21.3 13.4 6.1 25.2 12.3 7.7 14.1 8.7 9.5 5.2 5.8 8.4 14.5 8.4 17.0 12.6 12.6 31.6 9.3 15.4 7.7 3.3 2.0 1.0 4.6 3.1 6.9 8.2 6.3 6.2 2.8 6.3 9.5 8.6 0.5 11.2 3.9 3.7 4.7 4.3 10.8 11.7 11.7 13.7 8.9 9.7 9.7 12.1 9.5 8.9 PPCDC "FLJ14585, MDS018" ENSG00000138621 "Phosphopantothenoylcysteine decarboxylase" Q96CD2 15 75023555-75117462 "Enzymes, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 19.9;granulocytes: 40.4;monocytes: 18.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045667 Approved Approved Cytosol Cytosol "HPA045667: AB_2679412" "unprognostic (8.66e-2)" "unprognostic (1.07e-3)" "unprognostic (6.03e-2)" "unprognostic (2.57e-2)" "unprognostic (2.95e-2)" "unprognostic (6.53e-2)" "unprognostic (1.76e-2)" "unprognostic (8.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.53e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (1.60e-2)" "unprognostic (7.67e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-1)" "unprognostic (2.13e-3)" 10.4 18.5 7.7 11.1 9.3 16.7 14.5 10.8 10.2 8.4 10.8 16.0 15.1 9.4 16.3 13.3 17.5 10.9 12.1 7.8 7.3 7.9 12.5 12.0 13.9 14.0 16.8 5.9 9.2 22.1 14.4 11.3 8.9 11.0 12.0 9.3 15.6 17.5 8.0 10.5 8.3 11.6 6.1 13.6 18.0 10.7 9.7 11.3 7.4 11.0 11.5 16.5 14.2 9.4 4.2 19.9 40.4 18.1 4.5 5.6 4.2 5.9 11.2 4.7 3.6 2.8 2.6 4.0 6.0 2.7 8.1 6.4 6.5 16.2 6.8 10.8 3.0 6.2 7.6 10.0 4.2 23.8 9.2 11.9 6.9 7.0 8.1 6.9 15.5 3.5 6.7 8.3 12.8 6.4 8.0 53.0 5.8 11.4 4.1 10.7 7.5 5.2 6.9 9.2 14.5 6.1 8.6 11.3 3.3 8.8 12.4 12.9 15.3 9.0 3.6 8.3 5.8 4.2 10.6 16.2 10.6 11.2 5.1 17.6 9.3 10.9 6.5 40.4 3.4 17.5 5.6 4.2 3.1 3.8 4.9 2.3 3.6 4.3 39.3 4.5 18.1 19.9 3.3 4.2 7.7 9.3 10.8 10.2 7.3 7.9 16.8 5.9 11.0 11.3 PPCS FLJ11838 ENSG00000127125 "Phosphopantothenoylcysteine synthetase" Q9HAB8 1 42456117-42473385 "Enzymes, Predicted intracellular proteins" Ligase "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031361, HPA031363" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" 16000 "Nucleoli fibrillar center, Mitochondria" Nucleoplasm "HPA031361: AB_10602150, HPA031363: AB_2673844" "unprognostic (1.49e-1)" "unprognostic (6.71e-2)" "unprognostic (8.15e-2)" "unprognostic (1.55e-1)" "unprognostic (3.84e-3)" "unprognostic (1.68e-2)" "prognostic unfavourable (5.96e-5)" "unprognostic (2.71e-1)" "unprognostic (7.79e-3)" "unprognostic (9.13e-3)" "unprognostic (3.24e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-2)" "unprognostic (6.45e-2)" "unprognostic (2.32e-1)" "unprognostic (2.80e-1)" "unprognostic (4.30e-2)" 23.4 36.3 18.9 20.5 21.9 10.7 30.7 12.0 26.0 23.2 32.0 12.4 27.3 25.5 18.2 34.4 31.6 14.5 30.9 22.1 17.8 16.4 41.4 43.9 26.5 28.1 19.3 14.9 19.6 47.0 22.8 16.1 37.6 17.2 27.2 27.3 19.6 36.6 35.0 19.6 21.9 41.0 27.6 18.9 24.4 27.2 13.5 13.4 22.6 31.3 26.0 20.5 24.0 19.4 41.9 44.4 76.1 55.7 42.0 41.0 52.0 22.5 9.4 5.5 8.5 17.1 17.8 20.5 11.4 13.1 15.4 13.7 7.9 27.6 6.8 22.5 14.4 13.3 3.6 17.3 13.0 17.9 10.9 11.4 10.4 9.4 23.5 11.7 20.2 15.7 31.4 10.8 20.0 14.3 4.6 4.9 15.7 13.5 5.7 11.5 6.3 14.6 6.5 5.6 12.1 33.7 21.3 6.5 7.1 14.0 34.2 35.4 16.1 51.8 8.9 8.5 11.3 12.9 13.0 16.2 10.1 4.9 3.5 13.5 17.3 58.1 55.7 76.1 30.7 55.1 35.7 41.9 37.0 33.0 44.4 39.9 41.0 34.9 41.2 42.0 51.8 33.2 36.4 52.0 18.9 21.9 12.0 26.0 17.8 16.4 19.3 14.9 17.2 13.4 PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.6;testis: 20.2" "Cell line enhanced" "Detected in some" "A549: 3.5;HeLa: 5.1;SH-SY5Y: 2.9;SK-MEL-30: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "myeloid DC: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" "Plasma membrane" "Cytokinetic bridge" "HPA034577: AB_10602817" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (9.85e-2)" "unprognostic (3.84e-2)" "unprognostic (5.00e-2)" "unprognostic (2.38e-1)" "unprognostic (3.43e-2)" "unprognostic (4.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.89e-1)" "unprognostic (1.10e-11)" "unprognostic (5.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" 0.1 0.5 3.1 0.2 6.4 1.4 3.9 0.2 10.6 0.2 0.2 0.1 0.0 0.1 0.3 0.9 0.2 0.2 0.3 0.3 1.9 1.0 0.3 0.1 0.4 0.3 1.7 6.9 0.2 0.2 0.1 0.7 1.0 0.2 0.5 0.1 0.0 0.3 0.6 0.1 0.7 0.1 0.2 10.5 0.3 0.1 20.2 0.0 0.1 0.4 0.0 0.3 0.4 0.1 0.2 1.3 0.0 0.9 0.0 0.0 0.2 0.0 3.5 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 1.2 0.0 5.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.1 6.4 0.2 10.6 1.9 1.0 1.7 6.9 0.2 0.0 PPIA CYPA ENSG00000196262 "Peptidylprolyl isomerase A" P62937 7 44796680-44824564 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB004655, HPA058345" Uncertain "Secreted to blood" 420000000 "CAB004655: AB_425607, HPA058345: " "unprognostic (3.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.86e-2)" "unprognostic (9.27e-2)" "unprognostic (2.19e-2)" "prognostic unfavourable (2.27e-6)" "unprognostic (1.12e-3)" "unprognostic (3.30e-2)" "unprognostic (3.92e-2)" "unprognostic (8.68e-3)" "unprognostic (2.52e-1)" "unprognostic (6.35e-3)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" "unprognostic (7.84e-2)" "unprognostic (1.16e-1)" 92.0 90.3 147.0 80.4 124.3 105.9 169.0 88.9 148.0 111.3 143.5 81.6 52.9 73.9 74.8 125.1 176.5 76.3 80.4 60.2 132.0 121.9 149.2 214.3 95.4 137.1 123.2 88.3 74.2 103.2 93.1 58.3 96.2 142.5 83.0 149.1 68.1 84.7 102.3 68.4 114.7 105.1 113.9 120.8 137.0 73.1 62.4 59.8 228.2 130.2 123.4 191.2 94.3 93.1 129.8 158.5 35.0 83.1 76.0 117.7 180.3 85.8 115.3 146.5 106.3 122.8 186.7 48.3 125.9 197.8 241.9 237.4 127.9 131.7 194.2 64.9 160.3 117.5 188.3 241.1 223.2 111.0 137.3 78.4 132.9 121.8 99.6 158.9 81.9 136.6 165.6 171.4 188.4 245.6 161.1 157.1 248.7 122.3 174.1 281.4 167.2 159.0 125.1 88.7 247.0 328.0 121.5 109.7 90.9 106.1 304.4 82.7 163.2 217.0 109.1 124.7 120.3 83.4 165.0 114.7 226.4 327.7 108.7 180.9 188.0 23.4 74.5 35.0 94.9 83.1 102.0 129.8 97.0 97.1 134.8 103.9 80.3 88.2 9.2 76.0 77.7 158.5 117.7 180.3 147.0 124.3 88.9 148.0 132.0 121.9 123.2 88.3 142.5 59.8 PPIAL4A "COAS2, PPIAL4, PPIAL4B" ENSG00000263353 "Peptidylprolyl isomerase A like 4A" Q9Y536 1 120889746-120890405 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 3.5;intestine: 1.6" "Cell line enhanced" "Detected in many" "NB-4: 4.5;SK-BR-3: 4.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA058345 Uncertain "HPA058345: " "unprognostic (3.49e-3)" "unprognostic (2.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.42e-1)" "unprognostic (4.17e-1)" "unprognostic (1.77e-1)" "unprognostic (2.09e-1)" "unprognostic (1.42e-2)" "unprognostic (7.94e-3)" "unprognostic (1.72e-2)" "unprognostic (1.91e-1)" "unprognostic (7.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.83e-2)" "unprognostic (1.74e-1)" 0.3 0.8 1.0 1.4 0.2 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.0 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 3.0 3.2 0.6 1.6 2.2 2.4 3.5 0.9 0.0 0.1 1.4 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 1.0 0.7 0.2 0.0 1.7 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.0 0.8 0.0 0.0 0.3 0.2 3.7 0.3 0.6 1.7 4.5 2.4 0.0 0.8 1.5 1.9 0.0 0.0 1.0 0.3 0.3 4.6 0.4 3.0 2.5 0.7 3.0 1.2 2.9 1.6 1.3 0.9 2.4 2.6 1.5 3.1 0.2 1.6 0.6 1.4 1.2 1.4 3.0 2.3 2.4 3.1 2.2 1.5 2.4 0.0 2.2 1.2 3.2 2.4 3.5 PPIAL4C ENSG00000263464 "Peptidylprolyl isomerase A like 4C" A0A0B4J2A2 1 149583865-149584464 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 10.9;intestine: 5.5" "Cell line enhanced" "Detected in many" "NB-4: 14.2;THP-1: 16.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA058345 Uncertain "HPA058345: " "unprognostic (3.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (7.93e-2)" "unprognostic (5.98e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (6.61e-2)" "unprognostic (2.25e-1)" 0.0 3.3 2.7 0.1 0.0 1.5 0.0 0.8 5.5 0.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 2.9 0.2 0.0 0.9 0.7 0.3 0.0 0.0 0.0 0.2 0.5 2.9 0.0 1.4 0.9 0.0 0.0 0.3 0.0 9.1 9.7 1.9 6.0 4.6 7.8 10.9 3.5 0.3 0.4 3.1 0.1 0.3 2.0 0.5 0.4 1.0 0.7 0.0 4.8 1.2 2.1 0.0 3.9 0.0 0.2 0.6 3.5 0.0 0.5 0.0 0.0 0.1 2.0 1.9 0.1 0.5 0.6 0.3 0.0 0.9 5.3 0.7 0.4 5.2 14.2 6.1 0.1 5.2 0.0 8.9 0.2 0.0 3.9 5.4 1.1 11.1 6.0 5.2 16.6 1.2 3.5 5.5 3.3 8.0 4.2 5.5 9.0 3.8 4.6 7.7 0.9 4.3 1.9 5.4 6.0 6.0 9.1 6.1 5.7 9.4 7.2 5.0 5.9 0.0 4.6 5.3 9.7 7.8 10.9 PPIAL4D ENSG00000256374 "Peptidylprolyl isomerase A like 4D" F5H284 1 145241630-145242124 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Group enriched" "Detected in some" 4 "blood: 5.4;brain: 3.9" "Cell line enhanced" "Detected in some" "CACO-2: 2.1;NB-4: 1.9;SK-MEL-30: 1.7;THP-1: 1.4" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA058345 Uncertain "HPA058345: " "unprognostic (9.32e-2)" "unprognostic (1.33e-1)" "unprognostic (3.05e-2)" 0.0 0.0 0.5 0.0 0.7 0.0 0.0 3.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.6 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.0 0.5 0.1 0.0 0.2 1.0 0.0 0.0 0.2 0.0 0.0 0.0 4.5 3.8 0.7 3.7 1.8 4.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.5 0.0 0.9 0.0 0.9 0.4 0.0 0.0 0.0 1.7 0.6 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.9 0.0 0.7 1.4 0.3 1.2 3.7 1.4 4.5 2.7 1.7 3.6 3.1 2.8 3.5 0.0 1.8 1.8 3.8 4.1 5.4 PPIAL4E ENSG00000271567 "Peptidylprolyl isomerase A like 4E" A0A075B759 1 144372875-144373659 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "blood: 3.4;bone marrow: 2.7;skeletal muscle: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;HL-60: 1.3;NB-4: 1.4;SK-BR-3: 2.1;TIME: 2.0" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA058345 Uncertain "HPA058345: " "unprognostic (6.97e-2)" "unprognostic (5.22e-2)" "unprognostic (2.28e-1)" 0.0 0.4 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 1.9 2.0 3.4 2.9 0.6 0.6 0.5 0.5 0.1 0.0 0.0 0.4 0.2 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 2.0 0.1 0.6 0.3 0.0 0.6 0.4 0.2 0.0 0.2 0.0 0.0 2.0 1.0 2.9 0.5 1.9 1.3 1.6 1.3 0.5 1.7 0.5 0.5 1.9 3.4 1.5 0.6 0.8 0.6 PPIAL4F ENSG00000279782 "Peptidylprolyl isomerase A like 4F" P0DN26 1 144592868-144593527 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058345 Uncertain "HPA058345: " "unprognostic (1.08e-1)" "unprognostic (2.22e-2)" "unprognostic (2.02e-1)" 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PPIAL4G ENSG00000236334 "Peptidylprolyl isomerase A like 4G" P0DN37 1 148479824-148483679 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "brain: 6.9;skeletal muscle: 6.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA058345 Uncertain "HPA058345: " "unprognostic (2.17e-3)" "unprognostic (3.63e-1)" "unprognostic (4.83e-1)" "unprognostic (2.26e-1)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (3.95e-1)" "unprognostic (2.67e-2)" "unprognostic (1.79e-1)" 0.2 0.1 1.3 0.7 1.8 1.3 0.3 6.9 1.2 0.1 0.2 0.5 0.4 1.0 0.3 0.1 0.3 0.2 0.9 1.1 0.1 0.2 0.2 1.1 0.5 0.4 0.0 0.1 0.3 0.1 0.2 0.3 0.4 0.0 6.8 0.8 0.7 0.0 0.4 2.7 0.5 0.5 0.4 0.3 0.0 0.0 2.2 0.6 2.4 0.8 2.4 3.2 0.2 0.8 1.1 0.5 1.7 0.2 0.3 1.3 0.3 0.3 0.1 0.1 1.3 0.9 1.2 0.8 0.3 1.0 0.1 0.2 0.2 0.5 0.6 1.2 2.4 1.0 0.1 1.5 1.1 0.2 1.8 0.1 0.3 0.2 0.7 1.8 0.0 0.9 0.8 2.5 1.1 0.3 0.6 0.3 0.8 0.3 1.3 0.7 0.9 1.0 0.7 0.4 1.1 1.3 0.8 0.9 0.9 1.4 0.7 1.4 1.2 1.0 0.7 1.0 0.9 2.2 0.4 1.0 3.2 0.4 2.4 0.9 1.5 1.7 0.3 2.2 1.6 2.8 2.4 2.4 0.8 0.6 0.5 0.2 PPIB "CYPB, OI9" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155812-64163205 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Isomerase, Rotamase" "Disease mutation, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" 120000000 "Endoplasmic reticulum" Nucleoplasm "CAB011487: AB_443295, HPA012720: AB_1847399" "unprognostic (3.00e-3)" "unprognostic (5.65e-3)" "unprognostic (2.81e-1)" "prognostic favourable (1.56e-5)" "unprognostic (1.65e-1)" "unprognostic (1.07e-3)" "unprognostic (3.69e-2)" "unprognostic (1.27e-2)" "unprognostic (7.19e-2)" "unprognostic (8.80e-3)" "unprognostic (2.87e-1)" "unprognostic (2.79e-2)" "prognostic unfavourable (2.02e-11)" "unprognostic (7.05e-2)" "unprognostic (3.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" 56.9 64.3 23.9 49.3 26.9 54.9 48.1 15.1 32.1 75.3 44.1 35.4 102.8 42.0 64.2 106.9 48.0 54.8 58.1 44.5 23.8 27.3 89.5 285.9 57.2 63.8 29.7 19.6 67.5 193.7 26.7 71.8 120.2 27.5 51.0 47.7 36.2 123.3 95.4 19.5 33.1 57.5 54.3 30.7 78.0 47.7 27.2 29.5 53.7 154.3 45.7 69.1 49.2 51.7 63.5 191.6 41.0 51.1 44.9 71.6 87.1 39.3 49.5 44.7 101.6 156.7 91.0 39.3 94.0 123.5 74.4 88.5 71.2 73.1 37.6 76.4 145.5 64.2 81.7 63.1 38.4 23.8 30.8 53.0 54.7 93.1 164.3 52.9 48.0 83.8 68.1 43.4 105.8 89.8 37.0 131.0 56.4 62.8 16.1 81.1 39.0 31.8 30.9 47.5 191.8 77.2 61.4 25.3 39.9 43.0 74.0 68.4 44.2 161.8 55.2 74.4 61.7 41.6 63.4 71.2 68.9 39.5 69.5 85.2 74.2 41.0 51.1 33.9 71.6 39.2 71.5 63.5 50.5 58.1 67.4 38.0 33.0 44.2 25.5 44.9 25.2 191.6 40.1 87.1 23.9 26.9 15.1 32.1 23.8 27.3 29.7 19.6 27.5 29.5 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036741 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" 5700000 "HPA039163: " "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavourable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 22.5 13.7 3.3 10.8 3.6 0.0 29.9 1.6 4.2 24.3 30.0 3.6 26.6 15.7 20.4 32.7 35.5 9.0 25.8 43.7 4.0 2.7 27.4 24.0 16.3 9.0 3.7 2.1 13.3 24.3 8.7 5.8 28.3 10.0 17.8 22.0 5.3 25.9 18.0 18.4 12.0 35.2 37.9 5.4 8.9 13.5 8.0 3.2 2.5 42.7 29.6 12.9 31.5 21.5 0.0 1.1 0.0 0.1 0.0 0.3 0.0 4.6 4.1 1.6 33.8 58.8 27.0 6.7 13.3 10.4 6.9 14.3 6.8 31.7 0.0 23.7 35.8 5.3 4.6 16.8 5.6 0.0 8.1 6.7 15.4 7.8 15.1 0.0 3.7 16.9 12.9 8.1 8.6 14.3 1.8 0.0 4.9 27.8 0.0 0.0 2.9 7.1 0.0 3.6 0.0 21.9 16.3 2.1 3.7 26.1 12.7 2.8 17.8 14.9 15.8 13.4 8.4 4.6 5.7 0.0 0.0 0.0 11.6 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 3.3 3.6 1.6 4.2 4.0 2.7 3.7 2.1 10.0 3.2 PPID CYP-40 ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709134-158723396 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported Nucleoplasm,Nucleoli,Cytosol "Nucleoli, Cytosol" Nucleoplasm "HPA019520: AB_1847400, HPA019692: AB_1847401" "unprognostic (4.26e-2)" "unprognostic (2.03e-2)" "unprognostic (8.91e-3)" "unprognostic (8.17e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (1.46e-2)" "unprognostic (2.66e-3)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" 16.8 25.8 20.1 15.5 21.4 14.9 22.3 26.7 26.8 12.6 16.8 14.4 18.2 33.4 14.6 13.6 16.5 15.4 13.0 28.8 19.4 22.1 21.5 45.3 11.0 17.4 22.6 18.9 14.6 17.5 11.3 30.3 14.5 26.0 16.1 14.2 9.1 15.4 13.7 53.3 24.0 29.2 13.1 22.7 16.5 15.5 16.9 23.4 22.7 21.7 16.0 16.8 15.4 55.0 15.6 17.2 33.4 22.2 23.9 24.4 17.1 15.3 14.3 14.4 19.7 21.4 16.1 21.8 15.2 8.3 14.0 10.6 18.5 10.5 16.2 6.8 14.1 11.8 43.6 17.4 17.1 53.7 15.2 29.0 12.9 25.5 16.6 18.2 21.8 10.1 14.2 12.0 17.9 15.2 36.2 29.0 15.5 14.7 26.0 16.5 19.8 19.1 11.8 7.1 13.9 15.4 7.7 24.4 16.3 11.4 23.7 21.6 10.9 17.4 14.7 14.0 15.8 15.4 20.0 16.7 34.6 20.7 17.8 19.7 14.0 33.4 15.3 33.2 21.2 22.2 24.4 14.6 20.7 19.6 16.7 15.6 21.5 22.0 20.9 23.9 22.0 17.2 22.4 17.1 20.1 21.4 26.7 26.8 19.4 22.1 22.6 18.9 26.0 23.4 PPIE "CyP-33, MGC111222, MGC3736" ENSG00000084072 "Peptidylprolyl isomerase E" Q9UNP9 1 39692182-39763914 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019357, HPA020131" Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA019357: , HPA020131: AB_1847405" "unprognostic (2.94e-1)" "unprognostic (4.32e-2)" "unprognostic (6.34e-2)" "unprognostic (6.97e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "prognostic unfavourable (1.76e-4)" "unprognostic (3.52e-2)" "unprognostic (2.69e-1)" "unprognostic (3.88e-3)" "unprognostic (1.25e-1)" "unprognostic (9.29e-2)" "prognostic unfavourable (5.05e-5)" "unprognostic (5.86e-2)" "unprognostic (3.95e-1)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" 19.3 23.8 23.7 24.3 22.5 18.6 25.7 25.9 36.1 25.5 28.1 35.6 22.2 19.7 30.6 26.5 26.0 34.7 21.1 27.1 22.3 22.1 25.2 29.8 20.6 25.9 26.3 20.5 35.5 42.1 27.4 23.6 21.9 24.9 26.1 22.7 26.9 30.7 28.9 29.6 21.7 23.2 34.2 25.6 25.7 23.9 38.8 20.2 22.8 33.7 21.9 33.9 31.5 22.6 43.3 31.6 14.1 27.2 49.0 46.9 44.2 9.6 16.7 15.4 12.3 17.1 15.2 8.1 16.6 16.7 25.4 23.9 20.8 28.5 27.4 23.5 18.6 14.7 21.0 24.7 24.3 17.7 22.6 30.2 19.4 6.3 23.5 27.2 16.6 13.8 22.6 23.8 8.8 22.8 30.6 19.2 18.5 17.3 12.5 22.1 18.4 18.7 18.6 11.6 15.6 19.2 18.0 21.9 17.5 17.4 14.2 12.0 17.8 71.5 14.8 16.0 17.7 19.7 25.5 26.3 26.3 18.9 11.1 35.1 25.0 11.6 27.1 14.1 38.3 27.0 37.0 43.3 39.7 38.2 31.6 39.8 46.9 38.9 2.2 49.0 27.2 28.5 40.0 44.2 23.7 22.5 25.9 36.1 22.3 22.1 26.3 20.5 24.9 20.2 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355337 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 32.8" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria 27000000 Mitochondria "HPA077416: " "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 16.5 76.2 12.1 15.7 18.8 52.0 16.9 7.1 21.3 8.3 18.1 27.1 13.2 13.3 5.2 7.6 21.0 8.8 10.0 36.5 13.0 14.5 21.0 73.1 9.4 19.4 23.3 16.6 7.2 42.0 12.0 6.2 11.3 25.2 6.6 19.9 7.5 12.7 21.9 44.4 22.5 11.1 9.9 28.0 19.6 34.0 20.8 18.0 8.8 10.0 73.9 19.8 12.5 11.0 8.0 18.6 32.8 14.9 3.6 5.0 6.5 35.1 15.0 10.5 20.7 9.8 12.8 13.5 20.5 27.0 45.2 42.8 35.0 17.1 36.6 11.4 14.4 21.1 32.6 19.1 70.5 11.6 30.7 57.3 14.7 61.6 16.7 39.4 13.6 30.0 13.8 44.8 44.9 7.9 55.7 45.2 15.3 18.1 10.2 33.0 8.8 83.4 17.6 16.3 18.7 17.5 32.9 21.0 15.6 10.5 42.7 15.8 18.7 30.5 7.1 19.8 18.0 23.3 39.5 21.0 21.3 29.6 19.6 51.4 5.3 5.1 14.9 7.3 4.7 11.4 5.0 8.0 4.2 4.3 18.6 3.9 3.8 3.7 32.8 3.6 4.1 2.3 4.2 6.5 12.1 18.8 7.1 21.3 13.0 14.5 23.3 16.6 25.2 18.0 PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584340-169641406 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "HPA021788: AB_1847408, HPA057469: " "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (3.49e-2)" "unprognostic (1.55e-3)" "unprognostic (3.66e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-3)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "prognostic unfavourable (4.56e-4)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-2)" "unprognostic (3.39e-2)" 26.2 25.3 28.5 23.8 45.3 39.2 26.7 45.0 40.7 33.1 27.1 14.6 26.0 25.3 27.1 28.1 29.4 24.3 21.2 24.2 30.0 20.3 26.0 41.1 25.5 30.4 27.7 35.9 29.5 22.8 39.4 56.7 26.0 38.0 29.3 23.9 13.8 28.6 28.8 27.8 24.5 30.8 31.9 39.7 29.7 24.1 19.8 33.7 24.1 28.4 22.6 29.9 37.4 27.6 36.4 23.7 41.7 24.7 18.7 29.6 13.3 19.1 9.1 25.8 14.1 14.3 17.6 24.3 21.9 16.5 16.2 16.8 24.9 22.1 33.1 20.2 15.8 18.5 20.2 18.0 24.0 23.0 16.3 49.8 13.6 30.3 13.8 46.8 22.2 14.8 20.4 22.0 24.7 17.8 48.0 27.6 18.5 15.5 34.5 28.7 37.0 9.3 31.8 25.8 32.3 20.1 28.9 22.6 14.9 23.6 17.6 23.8 16.4 27.1 20.4 21.2 16.2 14.1 18.0 16.1 23.1 46.2 15.6 25.1 19.4 20.7 20.0 29.9 20.3 20.1 23.2 27.6 27.0 23.8 14.9 36.4 29.6 23.7 41.7 18.7 24.7 23.7 22.9 13.3 28.5 45.3 45.0 40.7 30.0 20.3 27.7 35.9 38.0 33.7 PPIH "CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP" ENSG00000171960 "Peptidylprolyl isomerase H" O43447 1 42658425-42676758 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059019 Approved "HPA059019: " "unprognostic (7.93e-3)" "unprognostic (5.49e-3)" "unprognostic (2.53e-2)" "unprognostic (6.42e-2)" "unprognostic (3.79e-2)" "unprognostic (1.95e-2)" "prognostic unfavourable (1.55e-5)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (1.82e-2)" "unprognostic (2.84e-2)" "unprognostic (3.40e-2)" "prognostic unfavourable (1.78e-9)" "unprognostic (6.59e-3)" "unprognostic (4.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" 17.5 19.7 20.4 35.7 19.6 40.7 21.4 23.9 23.3 19.5 24.0 20.9 14.7 18.0 29.8 24.2 29.6 19.2 14.4 21.2 18.0 16.1 17.5 13.6 17.8 31.0 15.8 19.9 22.0 17.7 7.0 15.2 24.6 17.2 17.1 26.5 19.2 24.4 18.8 18.4 20.9 20.7 20.8 15.0 27.2 18.0 21.1 18.6 39.7 26.9 28.1 36.8 15.3 20.3 20.0 14.9 16.8 12.3 18.5 26.3 14.0 18.9 12.2 15.5 21.7 5.1 9.7 20.9 12.9 9.2 24.2 22.2 19.3 21.7 31.4 16.3 9.6 15.5 28.2 19.8 25.5 26.4 22.7 29.8 22.6 17.9 4.4 57.1 17.5 6.3 10.5 22.6 17.6 11.2 36.9 17.9 11.9 15.9 44.3 80.5 38.1 14.7 24.8 28.9 27.9 11.6 12.4 12.2 22.1 11.4 18.9 14.2 10.4 83.7 9.3 10.7 27.4 14.6 30.9 11.6 26.9 57.1 11.9 53.5 17.5 12.6 8.8 16.8 21.0 12.3 19.8 20.0 21.7 23.9 11.7 19.2 22.3 26.3 1.8 18.5 11.2 14.9 20.2 14.0 20.4 19.6 23.9 23.3 18.0 16.1 15.8 19.9 17.2 18.6 PPIL1 CYPL1 ENSG00000137168 "Peptidylprolyl isomerase like 1" Q9Y3C6 6 36854827-36875024 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062916 Approved Nucleoli Nucleoli "HPA062916: " "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-3)" "unprognostic (1.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.81e-2)" "prognostic unfavourable (1.28e-5)" "unprognostic (2.01e-1)" "unprognostic (3.37e-2)" "prognostic favourable (4.90e-4)" "unprognostic (6.58e-2)" "unprognostic (5.49e-2)" "unprognostic (8.99e-2)" "unprognostic (1.30e-1)" "unprognostic (2.30e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-2)" 9.0 17.2 15.9 11.1 23.1 7.3 12.3 16.6 18.7 11.1 10.2 13.0 5.7 8.7 13.7 11.7 13.1 17.5 7.5 29.7 13.2 19.8 17.6 34.3 7.5 13.4 15.0 15.5 13.2 36.7 10.6 19.4 16.0 15.3 11.2 13.2 11.0 12.0 12.5 11.7 5.6 8.2 17.4 15.8 10.3 8.5 14.0 11.0 10.2 23.5 13.4 17.4 12.2 8.1 7.7 6.6 1.1 4.4 5.0 15.0 6.9 14.1 11.2 29.6 19.7 4.0 8.4 16.0 14.4 9.6 21.7 18.1 19.6 9.4 21.7 18.3 10.1 11.5 35.0 24.0 24.9 18.1 29.2 25.8 7.3 25.9 13.2 22.0 10.8 6.3 11.4 16.7 31.3 19.4 48.3 10.6 15.7 13.4 26.1 10.1 19.6 15.2 21.1 25.9 19.5 12.9 10.0 31.5 16.6 9.6 10.3 18.9 15.0 18.7 11.8 16.8 15.5 12.8 24.0 11.6 30.3 39.7 5.3 40.8 31.9 1.1 3.2 0.8 11.2 4.4 15.0 7.7 9.3 10.7 6.6 6.2 10.5 12.3 0.9 5.0 2.1 5.6 6.8 6.9 15.9 23.1 16.6 18.7 13.2 19.8 15.0 15.5 15.3 11.0 PPIL2 "CYC4, Cyp-60, UBOX7" ENSG00000100023 "Peptidylprolyl isomerase like 2" Q13356 22 21666009-21700015 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "K-562: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035344, HPA055637" Supported Enhanced Nucleoplasm Nucleoplasm "HPA035344: AB_10672863, HPA055637: " "unprognostic (1.97e-3)" "unprognostic (3.61e-2)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (2.90e-3)" "unprognostic (5.16e-3)" "unprognostic (3.77e-2)" "unprognostic (9.46e-2)" "unprognostic (1.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-3)" "unprognostic (5.46e-2)" "unprognostic (5.39e-2)" "unprognostic (5.39e-2)" "unprognostic (1.54e-3)" 15.0 21.5 19.4 20.9 24.6 16.6 13.5 24.1 30.9 17.7 17.4 25.3 19.1 18.6 21.8 17.0 22.3 15.7 16.5 20.0 17.2 17.1 21.2 20.3 14.6 23.7 15.6 20.9 16.6 31.4 23.6 30.2 31.4 19.0 19.5 17.6 23.6 22.0 16.5 25.5 17.5 19.1 15.2 15.0 21.3 19.5 18.4 17.6 32.8 27.0 13.6 33.5 17.4 16.2 8.7 11.7 4.8 17.3 12.8 13.2 9.1 6.5 6.8 8.0 8.4 8.1 7.0 7.2 8.6 6.1 10.5 9.0 6.9 4.3 11.2 5.2 9.5 9.6 10.6 7.3 6.3 6.9 10.8 10.5 6.8 8.1 5.9 16.5 9.9 7.5 6.6 7.5 5.7 9.0 69.7 8.1 7.5 10.2 7.4 4.5 7.6 4.2 9.6 11.8 2.3 5.3 6.6 12.4 6.8 7.8 12.4 2.8 8.9 5.5 10.9 6.6 10.7 7.7 5.4 9.4 6.8 8.5 7.5 6.3 7.9 1.0 8.6 4.7 9.5 13.9 11.4 7.0 11.1 12.0 11.7 8.7 9.8 8.9 4.8 12.8 17.3 11.1 13.2 9.1 19.4 24.6 24.1 30.9 17.2 17.1 15.6 20.9 19.0 17.6 PPIL3 CyPJ ENSG00000240344 "Peptidylprolyl isomerase like 3" Q9H2H8 2 200870907-200889303 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040765, HPA062187" Approved Supported Nucleoplasm 35000 Nucleoplasm "HPA040765: , HPA062187: " "unprognostic (8.96e-3)" "unprognostic (6.07e-2)" "unprognostic (5.34e-2)" "unprognostic (8.16e-2)" "unprognostic (2.69e-2)" "unprognostic (9.61e-2)" "unprognostic (8.31e-2)" "unprognostic (8.05e-2)" "unprognostic (1.40e-2)" "prognostic favourable (1.19e-4)" "unprognostic (5.23e-2)" "unprognostic (6.60e-2)" "prognostic unfavourable (5.16e-4)" "unprognostic (1.14e-1)" "unprognostic (5.96e-2)" "unprognostic (2.21e-2)" "unprognostic (4.87e-2)" 12.4 17.9 18.1 15.5 19.2 24.2 21.1 20.1 20.2 19.4 16.4 18.4 21.1 12.7 17.2 24.3 25.4 19.1 15.9 17.6 17.5 21.8 15.9 19.4 15.9 23.7 20.0 11.8 31.4 16.7 11.9 17.4 15.5 23.0 19.5 16.6 16.3 13.8 15.8 13.4 14.7 15.7 16.8 23.2 20.2 15.7 18.2 13.0 26.3 23.7 19.4 25.5 28.6 13.6 23.4 21.7 18.7 14.1 20.6 20.6 10.7 7.9 7.1 22.0 9.5 17.3 37.1 7.2 12.8 13.8 14.7 14.9 5.2 15.2 7.6 13.5 13.7 10.5 7.6 15.5 13.2 16.2 18.5 32.4 19.9 35.0 8.9 31.0 16.5 13.4 15.3 12.0 19.1 9.8 25.6 18.8 18.8 12.7 23.8 24.7 13.4 11.4 9.0 12.3 12.1 19.4 12.4 9.1 8.5 12.9 12.2 20.5 10.2 14.1 13.3 21.3 12.0 12.6 10.5 20.6 19.5 36.1 16.2 13.9 13.4 18.7 12.7 12.7 12.7 10.8 18.5 23.4 15.6 13.7 21.7 18.9 19.1 20.6 3.0 20.6 14.1 17.9 20.1 10.7 18.1 19.2 20.1 20.2 17.5 21.8 20.0 11.8 23.0 13.0 PPIL4 ENSG00000131013 "Peptidylprolyl isomerase like 4" Q8WUA2 6 149504733-149546038 "Enzymes, Predicted intracellular proteins" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031599, HPA031600" Approved Enhanced Nucleoplasm Nucleoplasm "HPA031599: AB_2673950, HPA031600: AB_10600928" "unprognostic (6.12e-2)" "unprognostic (4.90e-2)" "unprognostic (3.85e-2)" "unprognostic (8.42e-2)" "unprognostic (7.53e-2)" "unprognostic (6.36e-3)" "unprognostic (2.91e-3)" "unprognostic (2.22e-1)" "unprognostic (4.22e-2)" "unprognostic (1.09e-1)" "unprognostic (2.38e-1)" "unprognostic (4.62e-2)" "unprognostic (3.88e-2)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (8.50e-2)" "unprognostic (7.94e-2)" 20.0 20.1 20.6 15.0 35.5 30.6 21.2 35.1 27.8 24.0 15.3 19.7 10.1 14.1 21.1 27.2 15.7 18.0 19.8 18.3 21.3 15.6 18.8 23.0 17.9 15.7 20.9 18.0 32.9 16.0 20.8 36.6 22.6 23.9 20.5 16.8 15.7 18.2 16.7 14.8 15.4 16.0 20.0 22.7 17.6 16.0 15.9 19.4 27.0 26.8 8.2 16.8 22.0 19.2 21.4 16.6 24.9 17.8 28.7 24.6 14.8 10.9 5.9 20.7 17.1 12.3 16.2 19.3 21.7 20.7 23.7 25.4 12.4 11.3 11.6 15.0 16.7 10.0 15.8 8.3 37.7 16.8 14.9 12.8 13.0 21.3 19.4 23.3 10.9 12.6 14.2 24.2 20.3 12.9 27.8 7.0 18.4 11.7 13.2 20.0 16.3 9.3 17.9 19.1 5.8 18.0 8.4 12.2 9.4 25.8 11.3 14.7 13.3 17.0 15.1 15.7 12.4 27.8 20.6 9.3 4.7 18.2 13.3 18.7 22.7 24.9 16.1 18.1 14.7 17.8 20.4 21.4 19.5 16.9 16.6 16.6 24.6 18.7 13.4 28.7 16.1 16.2 20.7 14.8 20.6 35.5 35.1 27.8 21.3 15.6 20.9 18.0 23.9 19.4 PPIL6 "bA425D10.6, dJ919F19.1, MGC41939, RSPH12" ENSG00000185250 "Peptidylprolyl isomerase like 6" Q8IXY8 6 109390215-109441171 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 36.5" "Cell line enhanced" "Detected in many" "AN3-CA: 6.6;ASC diff: 10.6;ASC TERT1: 13.2;hTCEpi: 6.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036717, HPA058165" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA036717: AB_10671969, HPA058165: " "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (5.68e-2)" "unprognostic (2.68e-2)" "unprognostic (3.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (5.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.03e-2)" "unprognostic (1.42e-3)" "unprognostic (2.51e-2)" "unprognostic (4.71e-2)" "unprognostic (1.95e-1)" "unprognostic (3.29e-2)" "unprognostic (5.86e-2)" "unprognostic (2.32e-1)" 1.5 1.4 5.5 1.1 8.6 0.7 3.6 5.0 4.8 4.6 1.7 7.2 7.4 1.9 3.8 12.7 2.0 36.5 1.7 2.6 6.0 5.4 4.9 1.2 8.9 1.1 3.4 3.2 6.3 4.3 6.6 7.6 1.6 18.3 1.8 1.6 2.6 2.8 5.0 3.9 1.7 1.1 5.4 3.2 1.3 2.3 20.4 5.3 0.0 17.2 1.4 1.1 2.9 2.0 5.1 1.7 2.0 1.3 1.7 1.3 1.1 1.8 1.1 1.2 6.6 10.6 13.2 1.2 0.0 2.4 0.6 0.2 0.1 1.8 0.0 0.5 0.6 1.2 1.0 0.0 0.4 0.5 0.9 0.5 0.1 0.0 5.3 0.6 0.3 2.7 6.3 0.2 4.0 0.8 0.9 0.4 0.4 0.6 0.1 0.6 0.2 1.3 0.8 0.0 0.6 5.1 0.1 1.5 2.5 0.2 0.3 4.4 0.5 1.0 0.4 0.1 0.2 1.1 0.2 0.3 0.1 0.1 2.2 0.1 0.4 2.0 1.2 1.2 0.9 1.3 0.9 5.1 1.2 1.1 1.7 3.2 1.1 1.0 1.6 1.7 1.1 1.7 1.3 1.1 5.5 8.6 5.0 4.8 6.0 5.4 3.4 3.2 18.3 5.3 PPIP5K1 "HISPPD2A, IPS1, KIAA0377, VIP1" ENSG00000168781 "Diphosphoinositol pentakisphosphate kinase 1" Q6PFW1 15 43533462-43590253 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039380 Approved Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA039380: AB_10673528" "unprognostic (8.72e-2)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-1)" "unprognostic (2.38e-1)" "unprognostic (2.78e-1)" "unprognostic (8.18e-2)" "unprognostic (5.78e-2)" "unprognostic (2.59e-3)" "prognostic unfavourable (8.57e-4)" "unprognostic (6.67e-2)" "unprognostic (2.85e-3)" "prognostic favourable (7.14e-8)" "unprognostic (2.67e-2)" "unprognostic (3.35e-2)" "unprognostic (5.92e-3)" "unprognostic (7.95e-3)" 1.7 5.2 3.4 1.8 6.4 1.1 3.4 28.4 7.0 2.8 6.1 9.1 2.2 5.6 3.7 3.1 2.5 2.1 3.6 5.0 2.5 1.4 1.4 2.0 3.3 3.0 2.9 13.4 7.6 0.9 3.4 6.5 4.7 2.7 6.3 7.2 8.8 2.3 2.8 2.3 5.3 4.5 5.0 3.0 3.3 2.7 5.3 3.2 4.3 2.8 3.5 3.8 3.0 8.5 5.6 4.9 9.1 3.0 1.9 8.5 4.2 5.4 6.1 9.0 6.5 8.1 8.0 6.5 5.8 23.2 9.6 18.5 6.2 7.8 7.6 12.0 17.0 3.5 6.9 13.6 12.5 3.4 16.3 7.4 11.5 6.5 8.6 11.9 4.5 6.6 4.5 7.7 2.4 6.1 9.8 5.0 4.0 6.7 15.4 14.9 4.6 11.0 10.5 4.2 19.3 11.5 2.8 5.4 6.4 6.7 10.3 2.6 3.2 9.9 10.1 15.7 5.1 4.3 1.4 0.0 2.7 2.8 3.8 5.3 3.3 3.6 3.2 3.6 2.7 2.5 1.0 3.5 2.1 2.4 0.8 3.0 PPIP5K2 "CFAP160, HISPPD1, KIAA0433, VIP2" ENSG00000145725 "Diphosphoinositol pentakisphosphate kinase 2" O43314 5 103120149-103212799 "Enzymes, Predicted intracellular proteins" Hearing "Kinase, Transferase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037895, HPA038442" Approved Approved Vesicles Vesicles "HPA037895: , HPA038442: AB_10673173" "unprognostic (2.18e-1)" "unprognostic (1.04e-1)" "unprognostic (2.36e-2)" "unprognostic (1.93e-1)" "unprognostic (8.83e-2)" "unprognostic (1.60e-3)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.60e-2)" "unprognostic (8.59e-3)" "unprognostic (1.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.32e-2)" "unprognostic (1.29e-1)" "unprognostic (4.06e-1)" "prognostic unfavourable (1.12e-4)" "unprognostic (8.80e-2)" 21.6 20.5 12.6 18.2 18.4 37.9 22.3 30.7 24.2 26.1 23.8 9.7 16.0 14.3 22.6 20.3 17.0 18.5 17.7 16.4 13.2 17.6 21.9 22.6 14.8 20.6 19.5 18.7 26.8 25.5 22.3 40.3 21.6 37.2 18.4 22.1 10.5 17.4 21.7 5.7 16.4 20.2 16.0 19.8 27.7 18.6 13.5 16.2 38.5 20.0 12.9 20.3 16.9 18.2 12.1 15.7 24.3 18.2 10.0 11.2 6.7 9.6 9.5 18.4 21.3 15.0 19.4 16.6 20.1 14.0 12.7 17.4 7.9 16.4 22.8 19.7 20.1 5.9 15.9 12.0 20.7 18.0 8.4 28.9 17.8 12.6 11.0 24.9 26.3 12.9 9.0 17.8 16.4 14.0 29.9 21.0 18.7 8.1 21.5 17.5 20.0 22.2 20.5 16.4 31.2 13.5 11.2 10.3 13.5 13.8 14.5 13.6 11.4 16.9 14.0 18.1 8.1 20.1 15.0 13.3 30.2 30.9 10.6 39.6 16.9 23.0 13.4 24.3 8.7 13.8 10.7 12.1 8.4 9.0 15.7 11.3 11.1 11.2 13.0 10.0 18.2 9.3 7.3 6.7 12.6 18.4 30.7 24.2 13.2 17.6 19.5 18.7 37.2 16.2 PPM1A "MGC9201, PP2CA, PP2Calpha" ENSG00000100614 "Protein phosphatase, Mg2+/Mn2+ dependent 1A" P35813 14 60245752-60299087 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029209 Approved Supported "Plasma membrane,Cytosol" 850000 Cytosol "Plasma membrane" "HPA029209: " "unprognostic (3.14e-1)" "unprognostic (2.14e-1)" "unprognostic (5.64e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-2)" "unprognostic (2.30e-2)" "unprognostic (4.50e-2)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.29e-1)" "prognostic favourable (1.57e-9)" "unprognostic (1.58e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" 16.2 11.7 13.8 15.0 18.3 64.0 15.1 20.5 28.6 15.5 32.4 13.3 9.4 19.1 17.4 12.7 15.2 10.7 10.8 37.1 13.5 16.1 22.8 26.7 14.6 11.8 15.6 19.1 12.1 13.3 18.2 12.2 15.8 24.3 16.5 19.4 12.3 18.7 13.5 56.1 16.7 25.2 15.0 13.8 11.6 14.9 29.7 12.7 23.4 13.3 11.6 13.4 15.2 16.5 4.0 2.7 8.0 2.1 4.7 4.5 1.9 47.8 10.8 9.4 8.0 14.4 13.4 12.0 13.2 15.5 9.8 9.3 6.1 14.1 28.8 12.6 14.9 10.7 9.7 13.6 17.2 25.9 5.5 17.7 7.7 9.5 12.1 20.0 12.7 11.3 16.3 11.5 15.8 9.6 9.8 23.0 11.9 21.0 26.0 4.7 8.8 9.1 9.4 21.8 9.3 11.8 23.0 16.0 12.0 13.7 16.0 11.1 16.1 8.8 13.2 20.5 20.5 8.9 9.3 17.9 10.1 33.7 9.4 7.9 10.3 6.7 1.8 5.1 3.5 1.8 3.8 1.7 2.8 3.1 2.7 4.0 2.2 2.1 8.0 4.7 2.1 1.6 4.5 1.9 13.8 18.3 20.5 28.6 13.5 16.1 15.6 19.1 24.3 12.7 PPM1B "PP2CB, PP2CBETA, PPC2BETAX" ENSG00000138032 "Protein phosphatase, Mg2+/Mn2+ dependent 1B" O75688 2 44167969-44244384 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016745 Approved Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA016745: AB_1855622" "unprognostic (5.49e-2)" "unprognostic (2.67e-2)" "unprognostic (1.11e-2)" "unprognostic (2.96e-3)" "unprognostic (1.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-2)" "unprognostic (1.58e-1)" "unprognostic (1.94e-1)" "unprognostic (2.25e-1)" "unprognostic (6.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (1.75e-2)" 23.7 13.8 31.2 12.2 33.8 24.7 15.2 32.6 25.2 16.3 18.2 26.0 13.6 13.2 15.7 20.4 14.9 12.7 14.3 21.1 29.6 24.6 19.4 27.7 13.4 16.6 34.6 22.4 15.8 20.9 34.6 17.9 12.1 22.9 20.7 19.0 24.3 16.4 16.4 72.0 12.5 14.3 21.1 27.3 16.1 14.8 13.3 34.1 19.1 15.0 13.1 16.8 18.2 15.9 6.5 5.5 11.1 5.0 4.7 9.5 1.6 17.3 15.5 20.7 15.1 25.9 12.1 23.5 13.5 15.6 14.0 12.4 20.9 11.3 19.1 21.2 15.5 9.5 23.1 8.8 20.8 19.3 9.0 20.2 9.3 14.3 20.9 18.0 16.9 11.6 15.5 11.1 18.9 11.4 14.7 20.3 12.5 14.4 17.8 29.0 25.5 5.2 19.0 23.1 12.8 32.6 17.6 16.7 21.0 12.1 18.2 15.6 9.8 12.6 10.4 12.3 17.7 10.1 12.9 17.8 11.6 17.9 6.5 30.0 8.8 8.3 3.3 11.1 7.2 4.5 6.2 5.8 6.9 6.1 5.5 6.5 9.5 6.4 9.2 4.7 5.0 5.3 6.2 1.6 31.2 33.8 32.6 24.9 29.6 24.6 34.6 22.4 22.9 34.1 PPM1D "PP2C-DELTA, Wip1" ENSG00000170836 "Protein phosphatase, Mg2+/Mn2+ dependent 1D" O15297 17 60600183-60666280 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022277 Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA022277: AB_1858839" "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "prognostic favourable (3.52e-4)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (5.12e-2)" "prognostic unfavourable (4.27e-4)" "unprognostic (5.50e-2)" "unprognostic (1.70e-2)" "unprognostic (6.07e-2)" "unprognostic (2.52e-3)" "unprognostic (3.46e-2)" "unprognostic (1.95e-3)" "unprognostic (7.33e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (1.98e-1)" 12.2 7.0 6.1 5.7 9.2 13.6 11.9 30.8 6.6 11.1 10.0 10.6 7.8 7.6 12.0 8.3 8.6 11.1 8.3 5.8 7.7 4.4 7.4 7.4 9.2 7.9 10.3 4.6 17.3 12.3 8.1 8.9 18.5 8.8 9.3 9.4 8.2 8.1 6.8 9.7 8.1 8.1 8.2 7.3 9.2 7.3 16.2 12.5 15.5 8.7 6.9 7.0 7.8 11.3 7.3 13.1 20.5 13.2 6.8 8.3 6.8 2.7 5.4 6.1 5.2 4.1 2.5 7.9 4.3 2.8 2.8 4.0 5.5 1.6 7.8 3.5 2.9 2.9 3.9 1.8 3.8 1.4 8.7 5.6 5.4 6.4 3.4 2.2 4.3 2.2 2.9 4.1 2.4 6.3 4.1 3.3 3.0 26.5 6.1 3.4 2.6 4.2 7.4 7.8 4.7 2.5 3.4 8.4 6.1 5.7 1.9 1.3 2.3 3.0 4.6 3.6 10.0 2.8 2.3 5.3 5.6 5.9 1.4 2.3 2.8 8.2 13.2 14.1 6.7 10.2 5.9 7.3 5.6 6.1 13.1 5.9 6.1 6.2 20.5 6.8 6.1 5.8 8.3 6.8 6.1 9.2 30.8 6.6 7.7 4.4 10.3 4.6 8.8 12.5 PPM1E "CaMKP-N, KIAA1072, POPX1, PP2CH" ENSG00000175175 "Protein phosphatase, Mg2+/Mn2+ dependent 1E" Q8WY54 17 58755869-58985176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 10.7;brain: 36.5;testis: 13.1" "Cell line enhanced" "Detected in some" "AF22: 10.0;HAP1: 16.2;MOLT-4: 7.6;SCLC-21H: 7.5;SH-SY5Y: 15.5;THP-1: 6.9" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 25 "basophil: 2.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018462, HPA019263" Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA018462: AB_1855623, HPA019263: AB_1855624" "unprognostic (2.50e-2)" "unprognostic (5.75e-2)" "unprognostic (8.12e-2)" "unprognostic (2.99e-2)" "unprognostic (5.30e-1)" "unprognostic (8.19e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (3.22e-2)" "unprognostic (5.24e-2)" "unprognostic (8.80e-5)" "unprognostic (4.97e-2)" "unprognostic (1.23e-7)" "unprognostic (1.05e-4)" "unprognostic (1.64e-2)" "unprognostic (1.27e-1)" "unprognostic (9.12e-2)" 0.7 10.7 15.0 0.8 7.5 0.7 0.7 11.9 23.3 1.0 0.7 3.6 0.0 0.8 1.1 2.2 0.7 3.3 0.8 2.3 36.5 5.4 1.9 2.4 1.0 0.9 3.2 9.2 1.0 1.7 0.8 3.4 0.6 10.5 3.2 0.7 3.5 0.8 0.7 0.6 0.7 1.0 1.3 2.7 0.8 1.4 13.1 2.0 0.0 0.8 0.0 1.0 0.6 0.6 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.5 0.0 0.0 0.7 0.0 0.0 0.8 1.1 0.0 0.0 6.3 0.1 0.1 0.0 16.2 0.0 0.4 0.1 4.8 0.0 0.1 0.0 1.1 0.5 2.1 0.3 1.3 0.0 0.0 0.0 1.6 0.0 0.0 2.8 7.6 0.0 2.8 0.8 0.0 1.3 0.0 0.0 0.0 7.5 15.5 0.2 0.0 1.0 0.0 6.9 0.0 0.0 1.9 0.0 2.3 0.0 0.1 4.3 0.2 0.0 2.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 7.5 11.9 14.0 36.5 5.4 3.2 9.2 10.5 2.0 PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919420-21952837 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 17.7" "Group enriched" "Detected in many" 7 "dendritic cells: 5.5;granulocytes: 17.7;monocytes: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" 780000 Nucleoplasm "Plasma membrane" "HPA030989: AB_10669549, HPA030990: AB_10601249" "unprognostic (6.26e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (2.51e-1)" "unprognostic (4.77e-3)" "unprognostic (4.88e-3)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-2)" "unprognostic (1.45e-2)" "unprognostic (4.81e-2)" "prognostic unfavourable (6.03e-5)" "unprognostic (6.44e-2)" "unprognostic (3.02e-2)" "unprognostic (3.30e-1)" "unprognostic (4.11e-2)" 25.0 15.6 14.0 21.8 14.3 24.3 18.4 16.9 16.3 18.1 13.2 7.6 12.5 9.6 17.6 9.7 23.6 12.3 13.1 17.0 13.9 14.9 13.2 8.5 21.6 15.1 11.6 10.1 14.4 10.7 8.3 7.7 28.1 14.5 15.6 4.9 11.2 11.2 16.5 15.8 15.5 11.1 15.4 15.5 31.4 10.5 6.7 10.9 6.2 10.9 15.1 10.2 15.8 37.6 0.7 5.5 17.7 13.9 1.7 1.4 2.8 9.1 9.8 6.3 6.1 3.5 6.2 7.9 10.4 6.2 9.2 6.3 4.4 3.7 5.5 13.0 7.3 11.0 2.7 6.4 3.3 7.8 8.8 21.3 4.5 4.2 5.8 7.8 5.8 5.8 1.9 9.0 4.2 35.8 54.2 2.3 11.8 8.4 4.6 6.1 2.6 10.7 7.0 16.2 1.6 3.1 3.9 2.5 9.8 9.9 3.3 8.5 4.1 5.5 30.1 11.1 11.3 10.1 9.9 4.6 3.7 6.1 11.2 15.0 21.2 0.0 7.7 3.3 1.0 12.9 0.7 0.7 0.7 0.6 5.5 0.6 0.7 0.8 17.7 1.7 13.9 1.4 1.4 2.8 14.0 14.3 16.9 16.3 13.9 14.9 11.6 10.1 14.5 10.9 PPM1G "PP2CG, PP2Cgamma" ENSG00000115241 "Protein phosphatase, Mg2+/Mn2+ dependent 1G" O15355 2 27381194-27409687 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035530, HPA035531" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA035530: AB_10670021, HPA035531: AB_10610283" "unprognostic (7.50e-2)" "unprognostic (8.89e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (2.27e-1)" "unprognostic (4.15e-2)" "prognostic unfavourable (3.14e-7)" "unprognostic (9.36e-3)" "unprognostic (7.73e-2)" "prognostic favourable (6.08e-5)" "unprognostic (3.74e-2)" "unprognostic (1.23e-1)" "unprognostic (7.46e-3)" "unprognostic (1.06e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (7.83e-2)" 12.7 17.0 9.9 19.9 9.2 19.4 30.2 10.9 19.3 17.9 14.6 9.1 16.9 12.1 26.8 12.5 19.4 19.2 17.7 13.6 8.8 7.6 12.6 18.6 14.7 20.2 9.4 8.0 13.4 18.6 13.8 13.2 11.4 8.7 10.2 16.4 9.1 16.4 18.7 24.1 10.9 12.2 14.9 6.7 14.7 14.1 93.3 8.4 25.8 14.1 19.1 22.5 25.2 17.3 20.2 40.3 24.5 29.1 22.7 38.3 19.0 50.1 41.4 30.4 23.4 19.4 15.8 28.1 31.3 20.6 37.6 30.2 63.7 26.6 59.2 23.0 22.2 27.5 51.1 35.2 33.8 24.7 41.5 57.6 30.2 67.3 17.5 56.9 24.4 17.1 20.4 38.3 30.9 35.9 48.2 18.4 28.5 44.9 42.2 61.7 44.2 29.9 43.7 63.7 31.1 25.3 35.0 40.9 46.3 28.1 31.1 22.4 17.2 18.7 28.8 28.2 34.1 24.6 47.4 40.2 45.0 93.6 22.0 46.6 21.1 22.1 17.8 24.5 26.9 22.3 26.5 20.2 28.7 27.9 28.5 18.0 21.7 22.4 9.1 22.7 29.1 40.3 38.3 19.0 9.9 9.2 10.9 19.3 8.8 7.6 9.4 8.0 8.7 8.4 PPM1H "ARHCL1, FLJ13253, KIAA1157, NERPP-2C" ENSG00000111110 "Protein phosphatase, Mg2+/Mn2+ dependent 1H" Q9ULR3 12 62643982-62935037 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;parathyroid gland: 36.6" "Cell line enhanced" "Detected in many" "CACO-2: 35.1;HMC-1: 28.3;SK-BR-3: 16.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 5.3" "Group enriched" "Detected in many" 11 "dendritic cells: 2.3;granulocytes: 5.3;monocytes: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020694, HPA044244, HPA058777" Approved Supported Nucleoplasm Nucleoplasm "CAB020694: , HPA044244: , HPA058777: " "unprognostic (3.41e-2)" "unprognostic (1.94e-1)" "unprognostic (9.51e-2)" "unprognostic (8.61e-3)" "unprognostic (1.44e-1)" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (5.85e-2)" "unprognostic (3.17e-1)" "unprognostic (1.78e-2)" "unprognostic (5.53e-3)" "unprognostic (2.19e-1)" "prognostic favourable (2.72e-5)" "unprognostic (3.90e-2)" "unprognostic (1.73e-1)" "unprognostic (8.04e-3)" "unprognostic (1.14e-1)" 2.6 2.1 10.6 1.6 12.4 3.1 5.7 37.1 16.3 8.5 2.8 14.0 12.4 3.6 6.9 7.7 1.1 7.5 9.1 2.2 13.0 12.2 11.7 3.9 3.2 1.5 14.3 9.0 9.4 4.9 36.6 13.3 7.1 8.5 15.0 3.6 7.7 10.2 11.6 1.5 1.2 2.1 2.2 8.9 1.3 6.2 1.4 15.0 0.5 3.8 0.1 2.1 3.4 1.2 0.0 2.3 5.3 1.7 0.2 0.0 0.3 0.5 5.4 1.0 0.0 0.2 0.0 11.9 1.3 1.3 0.8 0.2 35.1 2.5 0.0 1.2 0.6 0.7 3.8 0.1 0.5 0.1 1.9 6.6 1.0 7.9 0.0 2.0 28.3 0.0 0.1 0.0 0.3 0.1 1.7 0.0 0.6 4.0 0.6 0.9 7.1 2.6 0.9 2.5 9.8 8.1 12.4 3.1 0.0 2.2 16.0 5.2 8.7 1.1 0.1 0.2 0.7 0.1 0.4 1.4 9.0 1.8 0.1 0.0 0.5 5.3 1.7 3.0 0.0 1.4 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 1.2 0.2 1.4 0.0 0.0 0.3 10.6 12.4 37.1 16.3 13.0 12.2 14.3 9.0 8.5 15.0 PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715477 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 30.9;skeletal muscle: 45.1;testis: 31.9" "Cell line enhanced" "Detected in many" "T-47d: 20.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 9 "plasmacytoid DC: 30.9" "Lineage enriched" "Detected in many" 17 "dendritic cells: 30.9" "Region enriched" "Detected in some" 8 "olfactory region: 33.6" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles Vesicles "HPA046045: " "unprognostic (8.68e-2)" "unprognostic (5.65e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.93e-3)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-2)" "unprognostic (2.55e-1)" "unprognostic (9.30e-3)" "unprognostic (3.36e-2)" "unprognostic (7.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.28e-2)" "unprognostic (9.96e-4)" 0.8 2.3 6.4 0.9 4.8 0.8 1.9 7.8 6.8 0.9 0.7 2.1 1.6 0.7 1.4 14.8 3.0 2.4 1.3 5.4 4.3 4.8 1.2 0.7 0.7 2.4 3.7 4.4 1.3 3.8 2.4 1.1 0.8 3.9 1.4 0.7 1.5 2.3 2.3 45.1 13.3 0.6 1.3 1.6 1.3 0.7 31.9 0.7 1.4 1.6 5.3 1.9 1.6 1.5 0.4 30.9 0.0 1.7 0.0 0.0 0.3 2.7 0.1 1.5 1.7 0.8 1.6 1.2 0.3 0.7 0.3 1.0 1.2 0.8 0.4 0.5 0.8 5.0 1.1 4.6 0.4 0.0 2.7 0.8 0.2 0.1 1.0 0.0 0.2 1.8 3.1 0.9 4.8 2.1 1.0 0.0 1.2 2.8 0.0 0.0 1.7 2.3 0.1 0.2 0.0 2.8 0.1 0.8 0.2 0.6 4.5 1.3 20.0 0.0 1.2 0.3 2.9 0.0 0.2 0.1 0.0 0.0 2.4 0.6 2.7 0.0 0.1 0.0 0.0 0.6 0.0 0.3 0.0 0.0 3.2 0.4 0.0 0.0 0.0 0.0 1.7 30.9 0.0 0.3 6.4 4.8 7.8 6.8 4.3 4.8 3.7 4.4 3.9 0.7 PPM1K "BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm" ENSG00000163644 "Protein phosphatase, Mg2+/Mn2+ dependent 1K" Q8N3J5 4 88257620-88284769 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 59.1" "Cell line enhanced" "Detected in many" "Daudi: 27.1;Karpas-707: 23.6;U-698: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020066, HPA020862, HPA023891" Approved Supported Mitochondria Mitochondria "HPA020066: AB_1855628, HPA020862: AB_1855629, HPA023891: AB_1855630" "unprognostic (2.38e-2)" "unprognostic (5.86e-2)" "unprognostic (7.42e-3)" "unprognostic (6.70e-3)" "unprognostic (1.18e-1)" "unprognostic (1.17e-3)" "unprognostic (1.87e-1)" "unprognostic (5.88e-2)" "unprognostic (5.50e-2)" "unprognostic (1.41e-2)" "unprognostic (9.25e-3)" "unprognostic (6.56e-2)" "unprognostic (9.82e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" 3.6 6.1 19.2 8.8 17.2 5.9 9.3 21.1 26.8 12.9 3.8 12.5 2.5 3.0 21.8 5.5 7.6 14.1 6.0 59.1 23.1 14.6 11.8 5.1 6.5 14.5 21.6 15.9 22.0 7.3 10.4 8.4 6.4 17.0 11.1 4.3 4.7 7.1 5.3 8.3 1.9 6.7 18.2 15.0 10.9 5.4 12.3 19.4 7.3 5.4 1.9 15.8 6.5 8.1 31.8 38.8 5.5 3.4 7.9 16.1 7.1 2.1 0.7 2.8 4.9 4.2 5.5 1.1 3.4 6.3 11.6 13.7 5.6 0.5 27.1 3.8 2.2 0.2 8.2 2.6 4.6 20.9 3.4 4.8 2.1 5.0 3.3 6.6 2.6 3.6 1.3 7.1 6.2 1.9 7.2 23.6 3.3 3.1 8.7 3.6 1.7 1.1 5.0 4.6 10.3 4.0 0.9 2.2 1.9 2.1 0.2 2.5 11.2 1.8 0.3 4.0 2.1 1.3 2.0 7.4 6.8 22.7 4.4 5.4 6.7 5.5 2.9 2.3 12.4 3.4 16.1 30.4 11.8 12.4 5.5 31.8 11.7 14.1 0.9 7.9 0.9 38.8 13.3 7.1 19.2 17.2 21.1 26.8 23.1 14.6 21.6 15.9 17.0 19.4 PPM1L PP2CE ENSG00000163590 "Protein phosphatase, Mg2+/Mn2+ dependent 1L" Q5SGD2 3 160755602-161078907 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HDLM-2: 34.9;U-266/70: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 7.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019891, HPA019953" Approved Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA019891: AB_1855631, HPA019953: AB_2170360" "prognostic unfavourable (4.90e-4)" "unprognostic (7.29e-3)" "unprognostic (2.01e-1)" "unprognostic (2.59e-2)" "unprognostic (8.03e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (1.63e-2)" "unprognostic (2.49e-2)" "unprognostic (1.92e-1)" "unprognostic (4.51e-2)" "unprognostic (7.51e-2)" "unprognostic (2.69e-3)" "unprognostic (1.81e-1)" "unprognostic (2.39e-1)" "unprognostic (9.13e-3)" "unprognostic (2.07e-1)" 7.7 8.5 7.4 3.5 11.5 3.3 6.3 15.8 23.2 11.3 7.0 5.5 1.1 3.0 6.2 3.7 8.7 6.1 12.6 9.9 6.3 7.8 8.4 6.0 4.6 1.9 8.0 10.1 3.7 5.4 33.6 26.3 11.5 13.8 9.6 5.9 5.6 18.9 3.7 25.7 7.6 3.6 16.4 4.6 3.4 8.4 2.8 3.7 5.6 14.4 9.6 3.5 16.6 10.8 0.7 1.3 4.9 7.6 1.1 2.6 2.0 1.1 0.7 4.0 2.1 2.3 0.0 2.5 0.2 0.1 0.4 0.1 0.2 0.2 0.2 0.4 0.1 3.6 3.3 0.2 0.1 34.9 3.5 3.4 3.3 0.4 0.1 2.1 4.0 0.4 1.6 0.1 0.2 0.2 0.1 5.5 0.0 1.8 0.8 0.2 2.3 0.8 4.1 0.7 0.8 0.1 3.7 4.8 4.1 2.0 2.3 0.1 2.7 2.1 0.2 0.4 0.4 0.3 1.3 34.9 0.1 1.9 0.6 1.7 0.8 0.7 2.3 4.9 2.6 5.5 0.2 0.2 0.6 1.7 1.3 0.7 1.0 1.8 0.2 1.1 7.6 0.8 0.0 2.0 7.4 11.5 15.8 17.9 6.3 7.8 8.0 10.1 13.8 3.7 PPM1M "FLJ32332, PP2Ceta" ENSG00000164088 "Protein phosphatase, Mg2+/Mn2+ dependent 1M" Q96MI6 3 52245793-52250597 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.0;U-266/70: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA036905, HPA062291" Uncertain Approved "Nuclear bodies" "Nuclear bodies" "HPA036905: AB_10602818, HPA062291: " "unprognostic (4.26e-3)" "prognostic favourable (7.73e-4)" "unprognostic (2.55e-2)" "unprognostic (4.85e-3)" "unprognostic (5.64e-2)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "prognostic favourable (6.69e-4)" "unprognostic (4.63e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.61e-5)" "unprognostic (1.49e-1)" "unprognostic (4.14e-2)" "unprognostic (9.27e-2)" "unprognostic (4.37e-2)" 14.3 7.2 13.9 22.7 14.8 16.5 26.3 3.6 9.2 16.9 12.5 4.6 7.8 4.4 13.6 12.0 10.8 11.7 19.4 14.5 8.7 8.5 8.7 4.9 30.1 38.0 5.4 12.3 14.9 5.9 6.9 7.5 8.6 4.9 15.1 6.7 11.0 10.8 12.4 3.1 7.5 8.8 18.1 6.8 22.5 8.3 6.2 5.9 20.5 11.3 9.9 20.5 11.3 13.5 5.0 9.6 19.6 18.6 7.4 15.0 10.1 0.4 2.5 1.6 3.7 22.9 23.0 2.5 5.8 12.6 8.3 6.4 1.5 2.0 4.2 1.7 15.2 0.7 5.2 1.1 3.4 5.1 1.2 9.6 6.7 1.5 16.8 1.4 9.2 18.9 2.5 9.2 5.8 10.6 1.6 7.0 9.6 1.0 6.3 0.4 2.0 7.1 1.4 0.7 9.3 3.6 1.1 1.1 4.6 4.2 1.1 5.2 3.6 3.7 7.4 3.1 5.3 1.8 0.7 26.3 4.9 4.5 6.3 2.5 3.8 1.2 15.7 8.5 15.0 12.4 11.7 5.0 11.8 13.8 9.6 3.8 11.1 13.8 19.6 7.4 18.6 5.8 13.2 10.1 13.9 14.8 3.6 9.2 8.7 8.5 5.4 12.3 4.9 5.9 PPM1N FLJ40125 ENSG00000213889 "Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)" Q8N819 19 45488777-45502510 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood: 43.7;skeletal muscle: 81.9" "Cell line enhanced" "Detected in many" "RT4: 21.8" "Cancer enhanced" "Detected in many" "testis cancer: 11.3" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "non-classical monocyte: 43.7" "Lineage enriched" "Detected in all" 10 "monocytes: 43.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA043577 Supported Vesicles Vesicles "HPA043577: " "unprognostic (2.38e-2)" "unprognostic (1.11e-2)" "unprognostic (8.53e-2)" "unprognostic (6.59e-2)" "unprognostic (4.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-3)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.45e-2)" "unprognostic (9.27e-2)" "unprognostic (2.48e-2)" "unprognostic (1.11e-16)" "unprognostic (3.42e-2)" "unprognostic (1.79e-1)" "unprognostic (3.92e-2)" "unprognostic (1.86e-3)" 1.7 0.9 5.4 1.2 4.5 1.3 1.9 0.7 4.1 1.3 1.7 0.1 0.7 0.6 1.5 1.0 2.2 0.8 1.0 0.9 3.3 2.3 1.2 1.5 1.5 1.6 2.6 2.2 0.8 0.5 1.3 1.4 2.4 2.7 2.3 1.0 10.6 1.5 1.4 81.9 2.4 1.4 2.6 3.4 15.7 1.7 2.9 3.5 2.5 0.9 0.0 2.4 4.0 1.9 1.9 4.3 2.3 43.7 1.1 2.9 1.9 1.9 5.1 0.9 3.9 4.5 6.1 11.2 1.4 2.3 0.4 1.7 1.3 12.0 8.1 2.4 1.3 5.7 2.3 1.7 0.7 7.9 3.3 6.4 2.0 1.5 1.1 0.5 13.7 2.5 2.6 2.3 1.3 0.7 7.3 7.3 0.8 1.4 2.2 3.5 3.1 1.1 1.4 1.1 2.3 2.5 21.8 4.4 5.2 0.7 8.4 6.3 2.8 1.9 1.1 6.4 3.9 3.1 1.0 1.2 3.2 1.6 4.7 1.7 5.5 1.7 1.6 1.0 2.2 7.2 2.0 1.9 1.4 2.2 4.3 1.3 1.6 2.9 2.3 1.1 43.7 0.8 1.5 1.9 5.4 4.5 0.7 4.1 3.3 2.3 2.6 2.2 2.7 3.5 PPME1 PME-1 ENSG00000214517 "Protein phosphatase methylesterase 1" Q9Y570 11 74171099-74254703 "Enzymes, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 69.0" "Cell line enhanced" "Detected in all" "RH-30: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004541, HPA043900, HPA064396" Enhanced Supported "Nucleoplasm,Nuclear bodies" 16000 Nucleoplasm "Nuclear bodies" "CAB004541: AB_628161, HPA043900: , HPA064396: " "unprognostic (2.99e-2)" "unprognostic (1.27e-2)" "unprognostic (2.28e-1)" "unprognostic (1.98e-1)" "unprognostic (9.26e-2)" "unprognostic (5.77e-3)" "prognostic unfavourable (4.45e-6)" "unprognostic (2.31e-2)" "unprognostic (7.92e-2)" "unprognostic (9.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.06e-1)" "prognostic unfavourable (2.76e-4)" "unprognostic (1.84e-1)" "unprognostic (1.54e-1)" "unprognostic (4.14e-3)" "unprognostic (1.33e-3)" 9.4 16.1 13.3 6.2 27.6 8.4 9.3 27.4 38.5 11.4 9.2 13.5 9.4 7.1 13.1 16.5 13.5 15.2 8.9 12.8 14.6 18.3 12.3 6.5 8.2 5.5 13.6 18.6 12.4 10.4 69.0 13.6 15.5 22.4 15.1 9.8 9.6 11.9 15.9 21.0 16.2 7.4 13.4 12.7 5.0 8.3 22.9 9.3 8.6 14.9 7.9 8.5 11.4 10.2 7.5 11.3 10.9 9.6 12.2 14.0 8.4 9.9 13.0 8.9 9.4 9.3 7.7 8.8 14.6 9.6 27.7 22.0 28.6 6.6 5.3 10.2 10.8 16.6 13.2 10.0 26.1 7.4 5.0 7.9 14.1 12.2 18.6 5.7 7.0 7.4 8.2 14.7 6.4 8.1 18.4 4.5 48.4 6.6 6.7 6.1 7.0 10.4 8.0 90.6 8.0 10.4 6.9 12.2 10.4 17.5 8.0 20.5 14.7 5.9 4.9 11.1 13.3 10.6 11.2 8.5 10.8 9.4 8.2 5.2 9.0 1.3 8.6 10.9 10.8 9.6 13.3 6.9 13.8 12.7 10.8 7.5 14.0 11.2 5.0 12.2 8.5 11.3 9.7 8.4 13.3 27.6 27.4 38.5 14.6 18.3 13.6 18.6 22.4 9.3 PPOX "PPO, VP" ENSG00000143224 "Protoporphyrinogen oxidase" P50336 1 161166410-161178013 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030123, HPA054287" Uncertain Supported "Golgi apparatus,Vesicles" Vesicles "Golgi apparatus" "HPA030123: AB_10603987, HPA054287: " "unprognostic (1.17e-1)" "unprognostic (4.73e-2)" "unprognostic (9.88e-2)" "unprognostic (2.13e-2)" "unprognostic (3.24e-1)" "unprognostic (1.64e-2)" "unprognostic (9.58e-3)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.18e-3)" "unprognostic (7.12e-3)" "prognostic unfavourable (9.89e-4)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "unprognostic (1.80e-2)" 7.3 14.8 11.6 9.1 12.1 31.7 10.2 23.5 16.5 11.0 9.9 13.2 8.5 6.0 11.7 13.5 7.5 33.2 9.5 9.5 11.5 12.5 12.0 9.1 10.2 11.2 14.2 16.1 13.0 13.1 10.5 12.3 10.1 12.1 11.0 6.7 14.4 11.3 14.6 8.5 15.9 7.1 10.0 10.6 12.0 8.2 6.9 13.7 9.2 11.0 6.1 8.7 8.7 8.2 9.8 11.5 6.9 7.7 12.3 16.7 8.9 7.0 6.5 9.8 6.4 7.4 7.9 3.3 4.9 5.7 6.0 8.1 7.7 6.8 5.5 11.8 3.4 4.9 7.5 7.9 5.5 3.8 14.9 6.7 14.7 17.5 7.9 2.2 3.7 6.3 7.9 5.9 8.3 11.4 19.7 8.6 4.4 6.6 8.9 7.0 7.0 14.0 10.8 6.8 13.1 11.4 3.1 7.8 12.5 5.9 8.7 9.8 15.6 10.4 4.0 5.6 6.2 4.8 6.2 15.4 11.2 8.5 5.7 4.9 4.3 6.9 7.7 5.5 12.7 7.7 8.4 9.8 9.8 8.8 11.5 8.6 8.6 8.8 1.6 12.3 5.3 7.2 16.7 8.9 11.6 12.1 23.5 16.5 11.5 12.5 14.2 16.1 12.1 13.7 PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398183-67421183 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 177.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" 8100000 "Nucleoplasm, Plasma membrane, Cytosol" "CAB004545: AB_628177, HPA046833: " "unprognostic (1.03e-1)" "unprognostic (5.82e-3)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (3.15e-3)" "unprognostic (3.93e-2)" "unprognostic (2.07e-1)" "unprognostic (3.89e-2)" "unprognostic (5.05e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.96e-2)" "unprognostic (7.69e-2)" "prognostic favourable (1.17e-4)" "unprognostic (7.60e-2)" 28.4 35.4 24.2 42.0 32.3 42.1 25.1 19.6 33.4 23.9 39.6 22.1 29.9 33.9 19.6 25.8 59.7 22.8 28.6 33.0 21.8 17.1 43.7 55.0 27.6 49.3 19.9 19.9 20.1 53.3 23.1 21.6 44.0 19.3 27.2 33.2 23.2 49.7 31.1 39.0 34.4 47.3 20.5 21.3 53.7 35.1 15.7 19.4 77.7 38.5 40.5 63.9 25.5 25.7 78.8 76.6 126.2 118.0 68.2 113.9 177.2 46.2 53.4 31.7 46.6 15.8 19.4 32.3 22.9 26.9 46.3 35.2 76.3 55.9 39.8 39.1 34.8 40.5 36.6 47.7 28.5 41.8 24.8 38.2 25.2 40.0 34.5 48.5 49.4 21.8 31.6 39.4 23.2 46.4 35.5 33.0 37.4 105.5 61.5 95.4 52.5 42.3 43.7 43.9 34.5 45.4 38.3 24.8 41.2 26.6 47.8 70.7 57.2 33.6 33.0 35.7 36.6 42.1 29.6 33.1 30.6 45.2 42.8 33.4 37.6 81.4 80.1 126.2 88.6 100.5 69.3 78.8 79.8 90.5 76.6 77.0 49.1 69.2 93.3 68.2 118.0 54.4 113.9 177.2 24.2 32.3 19.6 33.4 21.8 17.1 19.9 19.9 19.3 19.4 PPP1CB "PP-1B, PP1B, PP1beta" ENSG00000213639 "Protein phosphatase 1 catalytic subunit beta" P62140 2 28751640-28802940 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022558, HPA065425, CAB069426" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" 7700000 "Nucleoplasm, Plasma membrane" Cytosol "CAB022558: , CAB069426: , HPA065425: " "unprognostic (2.90e-1)" "unprognostic (5.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-1)" "prognostic unfavourable (6.52e-6)" "unprognostic (3.47e-2)" "unprognostic (2.44e-1)" "unprognostic (3.15e-2)" "unprognostic (1.54e-3)" "unprognostic (3.95e-1)" "unprognostic (1.68e-1)" "unprognostic (3.66e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-1)" "unprognostic (2.26e-2)" 28.5 22.6 30.0 20.5 37.6 29.5 32.4 19.1 29.8 51.1 39.3 21.1 30.7 24.4 58.0 31.8 86.0 37.0 33.3 67.1 27.8 27.9 32.0 20.0 35.3 22.3 27.4 24.4 39.7 21.9 48.9 28.7 42.3 22.0 46.4 27.7 25.2 36.5 38.6 99.6 25.1 30.0 100.8 27.5 25.2 31.4 25.5 21.4 28.1 27.5 32.9 25.3 82.1 50.5 15.6 25.4 41.5 42.7 23.5 28.3 17.9 36.4 23.0 80.2 24.8 27.5 25.6 46.7 19.6 22.4 19.1 18.9 20.4 21.6 29.2 24.7 20.3 22.6 22.8 26.2 22.8 46.3 11.8 22.0 28.2 22.0 59.9 24.9 10.4 19.6 37.3 20.6 43.2 23.1 20.0 29.0 25.0 18.3 26.4 21.6 26.3 18.2 26.0 71.1 22.2 62.2 44.1 22.0 27.2 30.5 33.9 26.6 16.4 14.0 27.6 25.6 28.2 18.3 23.6 20.7 32.5 59.8 27.2 26.9 18.9 22.5 24.8 32.1 16.8 37.8 21.3 15.6 25.5 19.6 25.4 13.4 22.7 25.5 41.5 23.5 42.7 19.6 28.3 17.9 30.0 37.6 19.1 29.8 27.8 27.9 27.4 24.4 22.0 21.4 PPP1CC "PP1C, PP1gamma" ENSG00000186298 "Protein phosphatase 1 catalytic subunit gamma" P36873 12 110719680-110742939 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022645 Uncertain 7600000 "CAB022645: " "unprognostic (1.51e-1)" "prognostic favourable (7.44e-4)" "unprognostic (4.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.29e-2)" "unprognostic (7.26e-2)" "prognostic unfavourable (2.75e-6)" "unprognostic (6.55e-2)" "unprognostic (4.11e-2)" "unprognostic (6.91e-2)" "unprognostic (4.96e-3)" "unprognostic (5.72e-2)" "unprognostic (2.92e-3)" "unprognostic (1.66e-2)" "unprognostic (1.71e-1)" "unprognostic (8.96e-2)" "unprognostic (1.18e-1)" 23.3 29.4 27.4 23.4 29.8 28.8 24.1 31.9 32.3 25.2 63.3 22.2 15.4 63.0 25.9 19.8 31.3 22.9 21.5 66.5 29.4 21.0 19.8 20.6 19.6 41.4 32.0 21.9 31.7 38.8 19.6 25.8 17.0 25.9 26.1 36.4 28.7 26.9 19.4 63.4 24.0 73.3 46.3 25.9 27.1 25.2 43.7 28.3 42.3 25.9 18.3 41.3 37.9 23.2 17.8 19.1 30.8 19.1 8.5 14.9 12.5 45.0 27.2 46.6 34.0 28.3 39.1 35.6 26.0 38.8 43.3 34.7 46.4 23.0 70.5 19.7 27.9 25.8 62.4 34.2 60.6 40.9 42.0 45.6 20.4 47.3 23.1 58.0 39.7 24.6 28.0 32.7 29.3 50.0 45.4 19.1 39.6 18.7 46.9 65.1 73.3 40.2 46.2 32.2 44.6 27.7 34.3 37.6 30.2 28.7 34.6 50.1 54.1 45.4 22.2 22.2 36.6 29.8 32.6 30.2 31.3 60.4 20.8 42.2 33.6 18.7 19.1 30.8 8.2 14.9 8.0 17.8 14.9 11.7 19.1 15.4 12.4 10.2 16.3 8.5 18.8 7.4 13.7 12.5 27.4 29.8 31.9 32.3 29.4 21.0 32.0 21.9 25.9 28.3 PPP1R11 "CFAP255, HCG-V, HCGV, TCTE5, Tctex5" ENSG00000204619 "Protein phosphatase 1 regulatory inhibitor subunit 11" O60927 6 30066709-30070333 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 93.3" "Cell line enhanced" "Detected in some" "A-431: 19.8;AN3-CA: 26.4;fHDF/TERT166: 14.7;HBEC3-KT: 16.6;HEK 293: 13.6;HEL: 15.9;RPTEC TERT1: 18.4;U-266/84: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043266, HPA060174" Approved Approved Vesicles Vesicles "HPA043266: , HPA060174: " "unprognostic (2.00e-2)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (4.24e-2)" "unprognostic (3.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (1.18e-1)" "unprognostic (2.81e-1)" "unprognostic (1.74e-3)" "unprognostic (3.33e-2)" "unprognostic (2.68e-1)" "unprognostic (8.36e-3)" "unprognostic (1.74e-1)" "unprognostic (3.31e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-3)" 36.0 18.2 18.5 8.3 21.6 4.4 12.9 9.8 31.7 11.0 27.0 17.3 7.9 33.2 16.0 93.3 26.8 33.7 23.9 16.8 16.6 17.6 18.2 22.6 12.9 13.2 15.5 14.5 26.2 33.1 5.9 8.8 21.1 14.6 13.6 4.6 14.0 20.4 8.8 39.0 37.0 28.6 9.4 13.4 16.0 27.2 18.1 11.4 16.9 20.6 10.9 29.6 15.8 12.4 2.6 2.7 4.4 3.5 0.8 3.2 1.8 19.8 0.0 0.0 26.4 11.7 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 16.6 0.0 0.0 13.6 15.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.4 8.6 0.0 0.0 0.0 9.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 17.6 7.7 0.0 0.0 0.0 2.9 2.6 4.4 1.7 3.5 2.0 2.1 1.9 3.1 1.3 2.6 2.7 2.1 2.9 0.8 2.9 2.7 3.2 1.8 18.5 21.6 9.8 31.7 16.6 17.6 15.5 14.5 14.6 11.4 PPP2CA "PP2AC, PP2Calpha" ENSG00000113575 "Protein phosphatase 2 catalytic subunit alpha" P67775 5 134194334-134226142 "Enzymes, Predicted intracellular proteins" Meiosis "Hydrolase, Protein phosphatase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003848, HPA043236" Approved "CAB003848: AB_562203, HPA043236: " "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.60e-2)" "unprognostic (3.35e-3)" "unprognostic (1.26e-1)" "unprognostic (3.21e-2)" "prognostic unfavourable (7.33e-5)" "unprognostic (1.59e-3)" "unprognostic (1.57e-1)" "unprognostic (2.02e-1)" "unprognostic (1.34e-2)" "unprognostic (1.31e-1)" "unprognostic (5.24e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" 26.0 30.5 37.6 22.0 41.0 57.9 26.0 54.2 56.6 23.0 27.3 29.6 15.6 24.8 29.8 20.4 39.6 21.9 24.7 47.9 39.8 38.1 31.7 33.2 22.7 29.1 35.0 35.8 23.4 23.9 44.5 20.6 44.0 47.5 22.3 26.4 18.4 23.6 23.7 43.1 32.6 26.5 31.6 32.8 30.4 21.8 18.8 24.1 45.6 33.2 30.5 39.9 26.9 24.5 29.2 41.1 39.0 33.4 38.9 37.5 43.8 38.3 32.2 46.1 24.8 24.1 25.9 32.4 36.2 31.1 55.2 55.8 61.9 30.1 33.6 34.1 33.4 20.0 44.3 52.3 64.7 30.4 25.3 23.8 37.8 38.4 35.7 23.5 21.6 24.0 36.3 43.2 43.1 38.7 23.4 25.2 41.8 27.5 37.2 23.0 25.2 19.5 33.4 45.9 32.6 33.2 43.2 36.8 25.7 37.3 14.0 40.5 28.5 27.8 27.2 31.9 18.0 25.5 51.0 22.7 40.6 53.1 21.5 31.2 32.9 20.3 33.4 39.0 26.7 33.0 34.1 29.2 30.7 35.6 41.1 28.6 35.7 32.7 38.7 38.9 33.3 22.0 37.5 43.8 37.6 41.0 54.2 56.6 39.8 38.1 35.0 35.8 47.5 24.1 PPP2CB PP2Abeta ENSG00000104695 "Protein phosphatase 2 catalytic subunit beta" P62714 8 30774457-30814314 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018600, HPA043236" Approved Supported Nucleoplasm Nucleoplasm "CAB018600: AB_675841, HPA043236: " "unprognostic (9.77e-2)" "unprognostic (1.30e-1)" "unprognostic (2.51e-2)" "unprognostic (3.82e-1)" "unprognostic (6.70e-2)" "unprognostic (7.79e-2)" "unprognostic (1.13e-2)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.89e-2)" "prognostic favourable (5.82e-7)" "unprognostic (9.24e-2)" "unprognostic (2.04e-1)" "unprognostic (1.39e-1)" "unprognostic (2.65e-3)" 26.7 21.0 61.3 11.9 54.9 2.6 28.7 32.0 46.2 28.8 24.1 30.7 19.4 21.7 34.5 37.5 29.7 28.2 23.1 27.2 57.3 43.7 41.0 35.7 27.7 8.4 52.6 39.8 48.0 22.9 33.7 14.8 27.4 47.7 23.7 24.5 12.5 19.5 29.1 27.4 18.0 31.2 39.0 49.7 15.0 18.9 18.8 48.2 6.3 44.5 14.0 14.0 17.7 34.3 5.8 7.9 5.1 6.5 7.3 4.8 1.7 22.0 19.2 33.7 12.9 33.7 30.7 18.8 29.5 27.6 30.7 32.1 20.2 16.2 10.7 29.0 39.3 13.3 20.0 33.9 41.3 6.7 10.6 14.4 13.1 20.3 38.7 6.4 8.2 27.1 38.8 25.9 29.0 36.6 22.1 11.4 51.6 10.8 17.4 8.2 24.6 11.1 12.2 13.6 8.0 41.0 17.8 32.4 13.4 13.6 14.5 28.4 7.9 11.0 38.5 26.5 19.9 8.7 24.3 5.9 7.6 12.7 22.6 5.9 33.8 4.8 5.0 3.3 4.2 6.5 4.8 5.8 3.8 4.2 3.5 2.7 3.8 4.6 5.1 7.3 3.0 7.9 2.8 1.7 61.3 54.9 32.0 46.2 57.3 43.7 52.6 39.8 47.7 48.2 PPP3CA "CALN, CALNA, CNA1, PPP2B" ENSG00000138814 "Protein phosphatase 3 catalytic subunit alpha" Q08209 4 101023409-101348278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Craniosynostosis, Disease mutation, Dwarfism, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.8" "Low cell line specificity" "Detected in all" "Cancer enriched" "Detected in all" 7 "prostate cancer: 98.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012778, CAB018581" Enhanced Enhanced Nucleoplasm,Cytosol 35000 Nucleoplasm Cytosol "CAB018581: AB_2168324, HPA012778: AB_1855660" "unprognostic (6.66e-2)" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.36e-1)" "unprognostic (1.56e-1)" "unprognostic (7.81e-2)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "unprognostic (7.87e-2)" "unprognostic (3.49e-3)" "prognostic unfavourable (3.82e-4)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (5.12e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-2)" "unprognostic (5.74e-2)" 12.2 9.2 22.7 7.4 71.8 7.7 10.6 42.1 52.4 9.4 9.5 4.8 9.8 5.8 6.2 6.9 7.4 7.2 6.8 4.3 36.0 13.5 5.8 8.4 10.0 6.7 10.1 22.1 9.6 4.7 7.0 4.2 6.6 11.9 34.6 8.4 2.6 10.4 21.1 23.7 11.4 6.4 7.9 7.5 6.9 11.0 5.3 13.0 3.8 6.8 6.8 8.9 8.4 6.8 27.7 18.3 44.3 14.9 22.3 15.5 6.6 19.4 13.8 3.8 7.4 21.6 16.4 7.4 21.4 19.7 8.7 9.2 7.9 24.3 9.2 9.0 19.3 9.7 13.9 28.5 14.8 22.6 6.4 14.7 19.7 10.2 15.8 23.5 7.5 16.9 15.0 18.9 21.7 16.3 5.7 25.5 13.9 23.3 4.9 17.7 6.4 8.9 9.0 34.9 10.7 8.4 15.4 30.3 11.5 17.7 15.2 10.2 13.6 13.4 18.9 20.6 23.4 18.8 14.1 11.9 12.2 16.4 11.4 13.3 5.5 24.6 11.8 24.8 13.6 11.4 15.5 27.7 12.9 13.1 9.9 23.4 6.2 12.3 44.3 22.3 14.9 18.3 8.6 6.6 22.7 71.8 42.1 51.5 36.0 13.5 10.1 22.1 11.9 13.0 PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436428-73496024 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 133.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA008823" Uncertain Approved Mitochondria Mitochondria "HPA008233: AB_1855661, HPA008823: " "unprognostic (3.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.28e-2)" "prognostic unfavourable (9.59e-4)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "prognostic favourable (6.96e-5)" "unprognostic (4.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" 17.3 16.1 40.0 11.7 36.3 7.6 22.5 44.5 42.7 13.4 16.1 7.9 9.5 10.1 17.0 15.0 14.0 12.3 12.0 16.7 39.7 20.5 11.9 9.1 9.8 13.1 18.2 40.7 17.2 10.5 19.3 16.8 10.6 21.1 16.8 12.8 9.5 10.4 17.6 133.0 10.9 9.4 23.0 18.1 10.0 10.7 11.6 11.9 8.4 10.1 10.0 14.3 14.1 14.4 4.2 5.7 4.8 3.8 4.5 10.6 2.7 19.1 10.6 19.0 19.6 27.3 37.9 9.1 17.6 24.2 17.3 17.2 6.7 9.9 17.0 5.7 25.4 10.3 15.3 13.5 24.4 23.8 12.6 7.3 9.6 12.7 16.4 16.0 15.1 26.8 16.3 16.3 22.0 11.9 9.0 20.1 34.8 6.0 14.3 14.9 7.7 31.0 9.6 10.3 8.0 16.8 9.3 10.2 11.8 10.3 25.9 12.9 19.4 15.5 13.0 13.8 12.7 11.0 23.8 13.4 36.6 11.9 17.1 23.1 7.8 3.2 2.9 4.8 6.2 3.8 7.3 4.2 6.7 6.6 3.0 3.0 5.3 7.9 1.7 4.5 2.3 5.7 10.6 2.7 40.0 36.3 44.5 42.7 39.7 20.5 18.2 40.7 21.1 11.9 PPP3CC "CALNA3, PP2Bgamma" ENSG00000120910 "Protein phosphatase 3 catalytic subunit gamma" P48454 8 22440819-22541142 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023396, CAB024950" Approved Approved Vesicles Vesicles "CAB024950: , HPA023396: AB_1855663" "unprognostic (7.66e-3)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "unprognostic (7.71e-2)" "prognostic favourable (6.80e-5)" "unprognostic (9.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.84e-2)" "unprognostic (4.05e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (4.00e-1)" "unprognostic (2.78e-2)" "unprognostic (1.64e-2)" 18.0 8.3 6.9 13.7 8.1 15.2 21.1 11.9 12.0 10.3 10.2 10.9 3.7 6.1 13.4 7.8 11.6 9.0 10.7 27.5 7.6 7.3 8.9 8.2 16.5 22.3 7.7 4.9 10.1 9.9 13.7 15.1 12.7 9.9 11.1 7.1 20.7 15.5 6.0 52.4 9.1 9.8 13.5 7.9 14.1 9.5 41.6 6.9 6.8 11.5 13.2 20.0 14.7 11.0 15.5 4.0 6.6 2.9 11.9 16.0 3.9 5.4 4.0 3.6 4.4 9.6 11.9 5.3 7.6 13.5 11.4 12.6 2.3 3.4 20.8 9.4 11.8 3.9 8.3 7.6 14.6 11.9 4.4 4.4 4.6 6.7 13.0 3.2 7.4 7.2 10.6 7.6 7.9 9.8 8.7 27.8 12.7 2.5 7.5 5.2 2.6 5.6 24.5 8.5 6.9 10.6 5.2 2.5 6.0 5.7 3.4 7.8 2.3 5.4 10.5 17.7 3.8 26.8 5.9 13.9 16.7 21.8 9.4 4.2 11.7 3.4 1.6 6.6 11.4 2.0 8.7 15.5 12.9 16.0 3.2 13.9 12.4 10.1 0.4 11.9 2.9 4.0 10.1 3.9 6.9 8.1 11.9 12.0 7.6 7.3 7.7 4.9 9.9 6.9 PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085377 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: " "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (5.79e-3)" "unprognostic (3.28e-3)" "unprognostic (2.60e-3)" "unprognostic (3.82e-1)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (9.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" 24.7 26.6 13.5 26.1 14.1 26.7 18.6 16.0 15.9 19.2 28.4 14.5 20.5 22.5 19.2 28.4 39.1 17.7 31.9 28.5 12.6 12.1 28.9 52.3 27.4 25.3 12.5 12.8 22.5 26.3 23.9 16.2 51.6 11.9 18.3 17.4 18.8 22.0 14.9 26.0 26.1 38.8 15.9 11.9 36.2 22.6 39.0 9.5 59.7 27.1 26.5 37.9 22.2 21.1 19.5 30.3 57.3 28.2 12.4 23.6 12.0 30.3 34.1 22.8 31.8 21.6 18.2 35.4 27.1 30.2 35.7 39.7 30.0 39.7 23.7 34.9 31.9 24.8 28.2 33.6 21.1 29.6 50.5 16.1 21.2 66.2 32.8 22.6 30.5 26.4 29.8 32.5 20.6 41.4 31.3 21.7 27.2 87.6 39.3 41.2 43.3 18.2 44.0 23.7 41.2 33.7 31.3 22.2 32.8 13.3 40.2 23.1 37.0 38.5 26.3 20.9 21.9 16.8 20.8 37.2 40.9 27.7 29.8 29.1 25.2 21.4 26.9 57.3 18.3 28.2 13.1 17.0 19.2 20.6 30.3 19.5 17.2 15.2 56.9 12.4 24.5 23.5 23.6 12.0 13.5 14.1 16.0 15.9 12.6 12.1 12.5 12.8 11.9 9.5 PPP5C "PP5, PPP5" ENSG00000011485 "Protein phosphatase 5 catalytic subunit" P53041 19 46346994-46392981 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022641, HPA029065, HPA056933" Approved Supported Vesicles,Cytosol 47000 "Vesicles, Cytosol" "CAB022641: , HPA029065: AB_10610284, HPA056933: " "unprognostic (8.25e-2)" "unprognostic (7.90e-2)" "unprognostic (1.44e-1)" "unprognostic (6.30e-2)" "unprognostic (5.92e-2)" "unprognostic (2.62e-2)" "prognostic unfavourable (3.45e-6)" "unprognostic (1.29e-1)" "unprognostic (1.04e-2)" "unprognostic (8.25e-2)" "unprognostic (5.56e-2)" "unprognostic (2.20e-2)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.37e-1)" 18.9 24.7 23.0 18.1 28.8 13.4 15.9 25.2 50.8 20.4 21.1 19.4 15.2 18.0 23.0 15.2 20.1 27.8 20.5 48.2 20.8 23.9 22.6 22.1 17.4 19.3 21.9 29.8 16.7 21.5 26.3 23.9 17.3 34.5 19.5 17.5 19.7 21.0 21.4 40.8 16.4 15.3 23.5 16.2 21.7 20.6 19.0 15.3 15.6 18.1 20.5 16.1 17.1 18.1 10.6 11.1 1.9 14.1 14.0 19.8 8.9 19.5 36.8 22.0 16.6 16.6 17.8 10.2 24.3 19.8 29.6 26.7 26.4 15.6 30.0 13.3 17.7 16.1 28.9 28.7 8.9 20.8 39.2 25.0 27.0 18.7 18.5 33.8 17.5 16.2 13.6 20.8 15.5 25.4 24.0 15.5 16.8 21.2 18.9 63.4 16.6 20.1 28.2 19.0 24.0 17.7 26.8 31.3 23.0 20.4 26.0 8.7 16.3 21.6 21.1 13.0 21.6 9.6 25.4 12.5 28.7 36.0 13.9 28.4 21.6 0.0 6.8 1.9 19.8 12.1 12.7 10.6 9.2 15.3 11.1 8.7 8.9 12.0 0.1 14.0 14.1 7.9 9.3 8.9 23.0 28.8 25.2 50.8 20.8 23.9 21.9 29.8 34.5 15.3 PPP6C PP6 ENSG00000119414 "Protein phosphatase 6 catalytic subunit" O00743 9 125146573-125189939 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050940 Uncertain "HPA050940: " "unprognostic (6.45e-2)" "unprognostic (4.01e-3)" "unprognostic (7.12e-2)" "unprognostic (5.36e-2)" "unprognostic (2.78e-2)" "unprognostic (2.92e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (2.44e-1)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "prognostic favourable (4.50e-6)" "unprognostic (1.54e-2)" "unprognostic (3.51e-1)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" 21.7 20.1 20.1 15.7 24.5 24.8 21.2 20.8 26.2 17.0 19.1 25.9 15.1 13.9 15.6 17.2 21.2 14.0 12.9 15.3 19.8 16.6 22.8 17.8 16.3 21.5 20.1 16.1 17.5 27.7 21.3 17.3 17.6 17.8 14.5 21.8 16.8 26.9 14.6 50.5 19.3 17.3 16.3 22.6 19.4 16.5 22.8 23.7 34.1 22.2 20.5 24.0 13.8 15.6 17.3 14.8 32.2 19.5 13.9 23.3 13.8 14.3 10.5 19.2 18.1 20.6 17.3 19.4 15.3 16.6 22.6 18.9 16.8 15.3 20.7 11.9 20.5 29.4 25.9 16.6 26.3 18.5 12.5 17.0 16.5 14.9 16.9 29.6 23.6 14.2 22.8 18.5 17.8 21.0 19.9 24.1 24.3 21.4 27.9 18.7 17.8 19.6 22.8 29.0 27.7 19.2 14.5 19.9 19.7 27.3 22.0 17.7 34.0 18.7 20.4 13.9 13.3 27.0 20.2 26.6 48.0 27.5 18.7 19.4 22.6 27.2 13.2 21.4 14.7 17.4 18.0 17.3 18.9 16.6 14.8 13.3 18.9 17.5 32.2 13.9 19.5 10.7 23.3 13.8 20.1 24.5 20.8 26.2 19.8 16.6 20.1 16.1 17.8 23.7 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40071461-40097727 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 86.0;THP-1: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" 130000 "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavourable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 33.3 27.1 37.6 31.0 41.5 33.3 39.7 35.2 41.0 30.3 21.0 31.5 17.2 12.9 31.3 19.4 18.5 20.7 23.2 18.1 32.7 35.8 29.4 18.4 47.3 48.5 35.3 29.1 24.7 17.4 30.4 21.2 25.9 34.6 28.0 26.0 26.3 22.1 23.6 8.3 13.8 16.6 36.5 33.6 61.3 17.9 13.8 29.1 19.8 18.7 14.4 30.0 23.0 19.8 9.3 77.4 59.9 90.0 7.2 19.1 91.6 10.0 6.8 11.0 6.2 13.3 11.4 21.6 5.6 10.2 13.6 16.8 39.2 16.9 11.5 11.0 5.9 17.7 17.1 10.1 18.7 14.5 17.6 6.0 16.8 19.3 15.1 13.5 14.5 10.7 11.1 10.8 10.1 18.3 13.9 16.8 7.6 20.1 7.7 10.1 20.8 10.6 8.7 14.8 20.0 9.5 18.0 8.8 9.3 11.0 86.0 34.2 12.5 159.9 6.4 6.6 14.2 6.2 16.7 15.1 31.6 11.1 8.5 33.0 12.0 6.2 90.0 48.2 9.9 77.6 11.8 9.3 14.7 11.5 77.4 9.2 19.1 14.7 59.9 7.2 58.3 7.6 16.8 91.6 37.6 41.5 35.2 41.0 32.7 35.8 35.3 29.1 34.6 29.1 PPTC7 TA-PP2C ENSG00000196850 "PTC7 protein phosphatase homolog" Q8NI37 12 110533245-110583320 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 53.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039335, HPA040614" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA039335: AB_10805474, HPA040614: AB_10795526" "unprognostic (2.44e-1)" "unprognostic (2.38e-2)" "unprognostic (1.11e-1)" "unprognostic (9.44e-2)" "unprognostic (2.38e-1)" "unprognostic (3.46e-2)" "unprognostic (2.14e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-2)" "prognostic unfavourable (1.43e-5)" "prognostic unfavourable (6.76e-4)" "unprognostic (1.09e-1)" "prognostic favourable (4.48e-5)" "unprognostic (5.34e-2)" "unprognostic (2.83e-1)" "unprognostic (5.01e-3)" "unprognostic (1.83e-1)" 10.4 15.3 6.5 10.3 9.6 26.2 10.3 8.3 12.9 9.7 11.8 5.7 4.9 7.5 9.3 4.6 12.6 7.8 8.8 35.3 9.0 9.0 12.6 11.9 13.1 10.9 10.4 6.8 8.9 7.5 13.0 12.7 6.9 15.3 7.7 9.8 8.0 12.9 8.2 53.8 13.4 11.7 13.1 7.4 9.4 8.4 8.2 6.5 16.1 8.0 15.5 13.1 12.4 12.4 2.1 1.4 6.1 1.7 1.7 2.4 0.6 12.0 6.9 5.9 6.2 14.8 13.1 8.5 5.6 7.4 6.1 6.2 7.8 4.8 21.2 5.8 5.4 11.8 11.9 12.9 12.4 15.4 9.8 18.8 7.4 8.4 14.1 20.7 15.5 11.2 21.3 8.6 25.5 11.6 13.9 6.1 9.9 3.1 18.3 17.8 8.4 12.9 15.3 8.0 12.9 25.4 13.6 9.6 7.5 10.5 14.6 12.3 6.9 11.1 13.2 5.6 6.0 17.1 9.3 17.6 19.4 23.7 9.5 11.5 11.0 0.1 1.7 1.3 2.3 1.5 2.4 1.3 1.9 1.8 1.3 2.1 2.2 1.9 6.1 1.7 1.1 1.4 1.3 0.6 6.5 9.6 8.3 12.9 9.0 9.0 10.4 6.8 15.3 6.5 PPWD1 KIAA0073 ENSG00000113593 "Peptidylprolyl isomerase domain and WD repeat containing 1" Q96BP3 5 65563236-65587549 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019353, HPA019360" Enhanced Supported "Nuclear bodies" "Nuclear bodies" "HPA019353: AB_1855668, HPA019360: AB_1855669" "unprognostic (3.31e-2)" "unprognostic (2.07e-2)" "unprognostic (6.78e-2)" "unprognostic (2.85e-1)" "unprognostic (9.61e-2)" "unprognostic (1.22e-2)" "prognostic unfavourable (2.19e-4)" "unprognostic (1.37e-1)" "unprognostic (4.97e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-3)" "unprognostic (5.72e-2)" "prognostic unfavourable (6.72e-4)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" 17.5 15.8 24.3 23.5 26.1 26.0 18.9 28.3 29.7 21.3 16.5 17.9 16.8 15.0 22.0 20.9 17.3 20.4 17.1 14.9 20.0 12.6 14.2 17.3 16.3 28.7 20.9 18.3 26.0 18.6 22.7 26.9 20.9 20.9 18.7 21.5 13.1 16.6 17.7 18.0 23.7 21.2 16.9 19.3 28.9 17.8 19.1 21.1 32.4 19.5 15.2 26.7 16.7 23.7 15.6 13.5 18.1 12.3 15.4 23.3 14.5 19.7 13.1 19.6 18.9 17.3 21.4 20.9 19.2 13.7 20.7 26.0 19.7 19.6 22.4 15.3 13.8 17.6 21.2 19.7 28.1 18.7 18.5 13.9 20.5 17.2 15.0 12.9 14.6 17.0 8.1 19.9 14.2 17.8 18.9 15.8 16.4 19.9 19.8 16.3 13.8 7.7 18.5 26.2 18.9 12.1 16.7 10.0 7.9 18.9 8.2 17.1 12.0 17.0 13.5 11.4 16.0 12.3 28.1 9.0 13.4 23.5 12.5 19.0 12.1 18.1 10.1 16.7 17.2 11.1 20.7 15.6 18.9 18.7 13.5 12.3 23.3 20.4 8.2 15.4 12.3 7.8 20.7 14.5 24.3 26.1 28.3 29.7 20.0 12.6 20.9 18.3 20.9 21.1 PRAG1 "DKFZp761P0423, NACK, PEAK2, PRAGMIN, SgK223" ENSG00000275342 "PEAK1 related, kinase-activating pseudokinase 1" Q86YV5 8 8317736-8386498 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4" "Cell line enhanced" "Detected in many" "A549: 28.1;NTERA-2: 18.2" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012066 Uncertain "HPA012066: AB_1847706" "unprognostic (7.04e-3)" "unprognostic (7.90e-2)" "unprognostic (2.32e-1)" "unprognostic (2.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.92e-1)" "unprognostic (1.05e-1)" "unprognostic (4.78e-3)" "unprognostic (2.64e-3)" "unprognostic (5.19e-2)" "unprognostic (4.95e-2)" "unprognostic (1.78e-1)" "prognostic favourable (4.81e-4)" "unprognostic (5.27e-2)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (5.22e-3)" 7.6 0.2 6.4 8.8 4.9 0.1 5.4 30.4 7.0 2.4 5.7 1.8 3.2 9.8 0.8 1.7 2.6 5.0 4.0 1.8 2.1 1.3 0.9 4.3 9.1 0.0 1.4 1.7 1.0 2.2 0.0 5.4 1.2 1.5 3.4 0.0 1.7 5.7 5.6 2.8 9.4 0.9 1.4 5.7 3.9 0.7 1.2 1.8 15.4 4.7 6.2 1.5 0.2 3.1 4.6 2.2 1.6 1.3 3.9 0.4 3.4 28.1 3.2 0.4 0.0 0.2 8.0 7.1 1.5 2.8 1.2 13.9 8.2 5.6 4.9 3.4 12.2 0.5 8.6 0.6 0.2 0.9 0.0 3.4 7.8 3.1 0.8 8.9 0.7 5.6 0.4 1.3 5.8 0.0 0.0 2.1 4.7 0.7 2.6 18.2 7.2 3.6 3.4 1.3 4.1 9.8 1.6 1.0 2.7 7.9 2.8 6.1 3.5 7.7 0.3 7.5 0.0 1.7 0.4 0.6 7.7 1.8 1.9 4.2 0.0 0.5 2.2 1.2 0.1 0.9 3.1 1.5 0.4 0.7 2.6 3.9 3.2 0.0 1.3 1.6 4.6 0.2 0.4 PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82823502-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" 34000000 Vesicles "HPA017065: AB_1855676, HPA071115: " "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.33e-2)" "unprognostic (9.22e-2)" "unprognostic (1.42e-1)" "unprognostic (7.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.88e-2)" "prognostic favourable (2.65e-6)" "unprognostic (7.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" 32.6 45.9 25.0 21.5 22.2 13.1 69.5 19.4 23.8 38.8 17.9 17.9 27.6 11.0 30.7 35.5 32.2 24.6 25.6 66.3 25.8 18.9 52.4 52.5 38.1 95.1 27.0 14.8 27.8 23.4 30.6 19.3 59.8 34.9 25.1 18.4 25.1 38.1 34.5 10.3 26.2 15.7 32.8 45.0 25.1 16.8 17.4 17.7 9.8 27.9 24.2 31.7 39.4 30.1 13.1 50.0 31.2 27.9 12.1 6.2 14.7 7.5 8.2 12.6 25.4 97.9 35.9 14.8 16.0 28.6 15.4 22.5 20.3 15.5 10.8 23.4 23.2 11.9 11.5 10.5 18.0 9.6 8.3 7.7 11.4 12.6 18.3 6.9 28.2 26.2 8.3 16.0 15.2 50.8 8.3 15.2 15.7 3.4 1.0 24.7 7.3 7.7 5.6 21.9 12.9 21.5 13.8 5.3 11.5 21.9 12.7 9.0 15.2 9.5 13.2 18.1 18.1 15.6 7.8 14.3 24.4 9.6 7.4 8.4 9.3 15.5 26.4 17.4 5.3 27.9 6.1 9.9 5.3 5.8 50.0 13.1 4.4 6.2 31.2 12.1 21.2 8.9 5.0 14.7 25.0 22.2 19.4 23.8 25.8 18.9 27.0 14.8 34.9 17.7 PRDM2 "HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2" ENSG00000116731 "PR/SET domain 2" Q13029 1 13700198-13825079 "Enzymes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005809 Approved Approved "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA005809: AB_1079673" "unprognostic (2.22e-1)" "unprognostic (3.28e-1)" "unprognostic (5.34e-2)" "unprognostic (1.28e-2)" "unprognostic (6.70e-2)" "unprognostic (2.72e-3)" "unprognostic (1.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.20e-2)" "unprognostic (2.53e-2)" "unprognostic (2.30e-1)" "unprognostic (1.35e-1)" "unprognostic (9.63e-3)" "unprognostic (3.81e-1)" "unprognostic (2.45e-1)" "unprognostic (1.85e-1)" "unprognostic (5.85e-3)" 15.2 14.5 26.0 17.2 28.1 64.1 17.2 32.3 44.9 16.2 18.1 19.8 12.6 12.4 18.8 16.4 19.6 14.4 16.4 14.3 19.8 14.5 10.8 9.3 15.6 23.4 18.9 27.8 30.7 12.8 16.0 26.7 15.7 18.0 17.7 13.6 10.3 15.8 18.9 45.2 21.6 16.8 16.8 21.6 16.9 14.2 17.1 17.8 14.4 23.3 11.7 22.7 19.8 19.3 16.0 5.4 9.7 5.1 5.7 5.7 2.5 6.7 3.9 14.1 5.4 11.2 8.6 6.8 8.9 5.4 6.1 6.8 6.1 7.7 20.8 7.8 8.5 8.4 10.5 5.2 6.7 12.8 7.5 13.9 4.5 2.8 6.1 4.6 12.0 9.1 9.2 6.4 5.4 6.0 12.3 24.1 7.6 3.4 7.4 7.4 4.2 5.2 10.4 7.6 6.2 3.5 7.7 12.3 7.9 7.1 4.5 9.7 6.4 7.5 10.6 7.8 8.5 7.1 4.8 35.4 24.0 29.8 6.9 10.9 10.0 3.9 4.8 6.8 5.7 3.1 3.8 16.0 4.5 5.2 2.9 12.5 5.2 4.5 9.7 5.7 5.1 5.4 4.1 2.5 26.0 28.1 32.3 44.9 19.8 14.5 18.9 27.8 18.0 17.8 PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089121-123194266 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 19.7;smooth muscle: 29.7;urinary bladder: 18.4;vagina: 18.7" "Cell line enhanced" "Detected in some" "BEWO: 6.8;HEK 293: 9.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 6 "pons and medulla: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA030324 Uncertain Approved Nucleoplasm Nucleoplasm "HPA030324: AB_10670032" "unprognostic (2.33e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-7)" "unprognostic (9.30e-4)" "unprognostic (1.10e-1)" "unprognostic (3.43e-4)" "unprognostic (1.27e-1)" 1.3 0.3 0.3 0.6 0.3 0.0 1.4 0.4 0.5 1.6 6.7 0.4 0.3 0.4 1.8 0.6 1.2 0.6 19.7 0.9 0.4 0.3 0.6 0.3 10.6 0.0 0.5 0.4 3.8 0.5 0.3 0.5 8.1 3.6 14.1 1.9 0.0 0.3 0.8 0.2 0.4 1.0 29.7 0.8 0.1 1.1 0.5 0.0 0.0 1.4 0.2 0.6 18.4 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.6 0.9 6.8 0.1 0.0 0.0 0.1 0.1 0.3 0.1 0.2 0.5 0.0 1.4 0.0 0.0 0.3 9.6 2.0 0.9 0.0 2.0 0.0 0.3 0.1 0.1 0.2 0.1 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.1 0.4 0.1 1.5 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.4 0.5 0.4 0.3 0.5 0.4 3.6 0.0 PRDM7 ZNF910 ENSG00000126856 "PR/SET domain 7" Q9NQW5 16 90056566-90092072 "Enzymes, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "testis: 4.8" "Group enriched" "Detected in some" 20 "REH: 8.9;SK-MEL-30: 6.5" "Cancer enriched" "Detected in single" 30 "melanoma: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA059944 Approved Uncertain "Nuclear speckles" "Nuclear speckles" "HPA059944: " "unprognostic (3.98e-1)" "unprognostic (8.89e-2)" "unprognostic (8.02e-3)" "unprognostic (8.26e-2)" "unprognostic (9.01e-2)" "unprognostic (5.61e-3)" "unprognostic (1.05e-2)" "unprognostic (1.46e-1)" "unprognostic (5.73e-1)" "unprognostic (5.52e-4)" "unprognostic (1.36e-1)" "unprognostic (1.61e-1)" "unprognostic (4.03e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PRDM9 "KMT8B, MSBP3, PFM6, ZNF899" ENSG00000164256 "PR/SET domain 9" Q9NQV7 5 23443586-23528597 "Enzymes, Predicted intracellular proteins, Transcription factors" "Meiosis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 4.1;epididymis: 3.3;testis: 8.3" "Cell line enriched" "Detected in some" 11 "U-266/70: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" HPA059555 Uncertain "HPA059555: " "unprognostic (1.23e-4)" "unprognostic (8.64e-2)" "unprognostic (2.18e-2)" "unprognostic (8.34e-2)" "unprognostic (4.11e-1)" 0.1 0.0 0.1 0.1 0.1 1.7 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 3.3 0.1 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.9 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.2 0.0 8.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.5 0.5 4.1 0.7 2.3 1.0 0.1 0.0 0.5 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.7 0.2 0.0 0.5 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.9 0.0 0.0 12.1 0.2 0.1 0.1 0.2 0.1 2.9 0.7 0.3 0.7 0.3 0.8 0.9 0.8 0.6 0.3 1.5 0.8 1.0 4.1 2.3 0.5 0.5 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PRDX1 "NKEFA, PAGA" ENSG00000117450 "Peroxiredoxin 1" Q06830 1 45511036-45523047 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004682, HPA007730" Approved Supported Mitochondria 110000000 Mitochondria "CAB004682: AB_437046, HPA007730: AB_1855204" "unprognostic (1.28e-2)" "unprognostic (4.64e-1)" "unprognostic (2.22e-2)" "unprognostic (3.65e-1)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "prognostic unfavourable (1.17e-5)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "unprognostic (4.68e-2)" "unprognostic (3.05e-2)" "unprognostic (2.90e-1)" "unprognostic (2.39e-2)" "unprognostic (5.99e-2)" "unprognostic (2.88e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (2.89e-4)" 43.3 58.2 71.0 43.8 57.4 12.0 75.5 31.6 60.0 46.9 51.1 72.2 42.6 78.5 40.8 75.7 136.1 49.7 46.9 84.2 56.5 73.0 121.7 136.5 52.9 51.0 99.1 51.2 43.0 20.4 34.1 34.3 58.3 87.8 42.2 53.0 48.8 53.5 52.2 78.9 46.9 77.6 52.4 98.3 46.5 52.5 25.7 72.6 29.7 130.1 114.3 91.0 49.1 56.3 44.7 50.3 64.4 64.5 20.4 72.3 58.7 65.4 120.6 49.7 63.2 56.4 48.3 106.4 74.4 77.4 80.8 67.2 59.9 28.3 57.8 78.6 79.8 67.8 107.9 71.9 80.0 44.5 83.3 43.7 170.2 167.6 24.5 50.5 57.2 41.4 53.8 80.2 19.0 92.6 79.8 20.0 80.2 52.5 67.7 49.3 155.8 126.4 119.4 62.7 76.1 145.2 56.4 66.2 33.3 68.3 185.5 4.8 50.4 40.9 78.7 32.3 73.1 69.1 99.0 14.0 78.1 110.1 53.4 35.2 18.9 64.4 55.6 18.4 28.5 60.6 37.5 44.7 45.5 37.9 50.3 36.2 28.3 31.0 2.4 20.4 64.5 33.5 72.3 58.7 71.0 57.4 31.6 60.0 56.5 73.0 99.1 51.2 87.8 72.6 PRDX2 "MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA" ENSG00000167815 "Peroxiredoxin 2" P32119 19 12796820-12801859 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" CAB008713 Approved 1100000000 "CAB008713: AB_1620974" "unprognostic (1.12e-1)" "unprognostic (1.98e-3)" "unprognostic (8.58e-2)" "unprognostic (4.40e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (2.44e-1)" "unprognostic (2.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.26e-2)" "unprognostic (9.18e-2)" "prognostic favourable (5.66e-11)" "unprognostic (7.01e-3)" "unprognostic (2.15e-1)" "unprognostic (3.51e-2)" "unprognostic (1.41e-1)" 39.8 95.1 54.7 17.9 55.6 119.1 27.7 52.1 80.8 22.5 39.9 27.8 42.2 53.6 28.1 33.8 49.9 31.5 36.4 142.0 49.2 54.4 44.5 79.4 15.9 22.7 62.2 41.6 40.0 43.0 32.8 49.4 20.9 70.9 30.6 30.8 35.9 42.3 41.5 136.8 44.3 44.9 27.6 27.5 18.1 31.5 13.7 23.5 38.9 36.8 69.9 29.5 31.5 24.6 42.1 24.6 9.5 20.6 23.3 76.8 72.3 44.8 0.1 62.0 80.2 9.0 6.2 45.7 20.8 20.7 28.4 16.1 47.2 11.3 13.2 48.7 20.0 42.9 39.1 33.7 8.2 56.5 61.8 23.9 63.6 70.4 24.3 0.0 0.1 26.6 15.5 21.3 10.4 26.2 51.0 20.8 10.8 81.4 52.8 20.3 45.7 86.9 52.3 0.0 63.6 37.7 48.7 76.8 60.7 49.3 50.6 16.4 45.3 34.4 11.5 21.3 17.9 59.1 45.0 25.5 24.9 60.6 20.2 8.0 4.8 2.8 20.6 9.5 53.6 14.3 56.2 42.1 73.5 54.8 24.6 29.2 74.9 58.5 2.7 23.3 15.4 14.4 76.8 72.3 54.7 55.6 52.1 80.8 49.2 54.4 62.2 41.6 70.9 23.5 PRDX3 "AOP-1, AOP1, MER5, SP-22" ENSG00000165672 "Peroxiredoxin 3" P30048 10 119167703-119178833 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008656, HPA041488" Enhanced 14000000 "CAB008656: AB_1620979, HPA041488: " "unprognostic (8.29e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (1.72e-3)" "unprognostic (4.62e-3)" "unprognostic (2.40e-1)" "unprognostic (2.06e-1)" "unprognostic (3.65e-2)" "unprognostic (1.29e-2)" "unprognostic (9.48e-2)" "unprognostic (6.03e-3)" "unprognostic (2.77e-1)" "unprognostic (2.77e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" 34.0 100.7 28.8 18.8 28.3 14.4 29.1 16.1 28.9 23.0 27.1 20.7 25.1 28.1 25.5 26.3 30.6 24.8 21.8 55.8 26.7 28.2 78.8 114.8 16.3 20.0 29.9 23.2 19.2 34.1 25.2 24.6 29.9 33.6 27.4 29.6 21.2 40.5 29.3 80.9 10.3 34.6 26.8 24.1 27.4 24.6 14.0 24.6 24.3 48.9 46.1 20.5 25.9 17.9 30.9 65.7 41.4 74.9 20.9 34.2 73.0 53.0 60.9 37.2 42.1 39.3 42.6 23.2 38.2 65.1 58.2 61.3 46.7 53.3 62.4 33.5 44.9 24.3 61.4 46.1 65.8 61.0 64.6 28.1 26.5 82.5 41.2 52.4 34.0 49.9 29.7 46.5 43.4 42.1 34.5 13.0 53.2 21.2 39.6 44.4 34.7 36.1 42.1 54.1 43.0 98.3 25.5 16.4 23.8 40.5 54.7 50.0 28.3 63.2 29.6 19.0 28.8 27.1 49.4 20.4 29.7 50.1 29.9 77.9 16.8 19.5 74.9 40.8 20.3 61.8 25.9 30.9 27.1 24.5 65.7 24.3 28.3 25.2 41.4 20.9 53.2 36.8 34.2 73.0 28.8 28.3 16.1 28.9 26.7 28.2 29.9 23.2 33.6 24.6 PRDX4 AOE37-2 ENSG00000123131 "Peroxiredoxin 4" Q13162 X 23664262-23686399 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "liver: 127.6;pancreas: 320.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008659, CAB027389, CAB047362" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" 11000000 "Endoplasmic reticulum, Cytosol" "CAB008659: AB_1620984, CAB027389: , CAB047362: " "unprognostic (3.82e-2)" "unprognostic (6.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.06e-3)" "unprognostic (1.64e-1)" "unprognostic (1.65e-2)" "unprognostic (1.29e-3)" "unprognostic (1.08e-1)" "unprognostic (8.32e-2)" "unprognostic (3.75e-2)" "unprognostic (2.97e-1)" "unprognostic (1.79e-1)" "prognostic unfavourable (1.33e-6)" "unprognostic (7.44e-2)" "unprognostic (1.29e-1)" "unprognostic (3.56e-1)" "unprognostic (4.10e-2)" 11.6 14.8 3.8 7.0 6.4 3.9 11.2 3.3 5.4 13.2 10.7 6.5 17.4 8.9 11.5 10.5 13.1 9.6 12.9 17.6 3.8 4.0 11.8 127.6 8.9 16.9 7.2 4.0 14.6 320.8 6.1 15.8 21.9 7.4 9.3 11.4 8.0 25.4 14.1 7.8 7.2 10.6 8.8 8.1 12.6 12.8 25.2 6.1 4.7 12.0 10.0 15.0 10.8 8.7 27.9 31.4 2.0 39.3 24.1 22.7 21.3 24.2 33.5 14.2 27.4 77.4 39.6 20.0 32.7 35.7 29.7 43.4 35.1 30.6 20.9 15.4 42.4 29.4 40.8 20.3 28.5 12.7 78.5 14.8 29.6 44.3 32.3 19.0 14.1 41.9 26.3 28.9 29.0 37.2 28.5 77.1 27.4 36.1 9.7 29.8 49.0 49.2 13.5 35.5 117.8 26.5 8.5 20.8 17.7 30.1 35.8 24.1 37.8 24.3 24.5 21.2 14.0 54.7 24.5 25.3 30.6 22.3 38.0 24.7 30.2 1.7 20.6 2.0 17.8 32.2 21.8 27.9 22.7 18.6 31.4 16.2 16.4 16.7 1.5 24.1 39.3 22.0 22.1 21.3 3.8 6.4 3.3 5.4 3.8 4.0 7.2 4.0 7.4 6.1 PRDX5 "ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10" ENSG00000126432 "Peroxiredoxin 5" P30044 11 64318088-64321811 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008661, HPA037915, HPA037916" Enhanced Enhanced Mitochondria 19000000 Mitochondria "CAB008661: AB_1620988, HPA037915: AB_2675735, HPA037916: AB_2675736" "unprognostic (2.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.33e-1)" "unprognostic (1.46e-1)" "unprognostic (9.43e-2)" "unprognostic (6.71e-3)" "unprognostic (1.08e-3)" "unprognostic (3.11e-1)" "unprognostic (9.30e-2)" "unprognostic (1.07e-3)" "unprognostic (1.57e-2)" "unprognostic (2.20e-1)" "prognostic favourable (1.24e-5)" "unprognostic (8.19e-2)" "unprognostic (2.30e-1)" "unprognostic (9.63e-2)" "unprognostic (5.03e-2)" 28.7 69.7 70.3 38.6 60.3 57.0 35.5 69.3 73.9 47.2 79.3 31.9 49.0 49.5 26.6 54.8 69.6 94.9 44.8 102.4 56.7 74.2 57.3 54.2 50.3 25.0 68.6 70.2 42.2 72.0 36.0 53.7 49.1 71.4 30.7 71.2 33.9 77.5 62.6 104.7 27.0 51.2 30.9 44.1 27.3 64.5 35.0 29.3 25.1 82.0 64.8 33.5 34.4 50.4 55.2 69.2 115.0 66.9 48.4 40.5 75.3 26.0 53.2 32.3 53.3 34.8 52.3 37.3 32.7 52.4 24.0 30.0 38.7 53.6 38.3 57.2 52.2 59.7 30.1 69.4 15.3 53.1 23.7 38.6 83.8 44.1 71.4 14.6 32.9 53.0 90.7 40.3 40.9 36.5 21.7 91.0 33.8 66.2 25.5 63.5 48.9 68.2 24.6 33.1 135.2 90.0 51.8 27.4 52.0 27.3 60.7 93.2 44.4 33.3 35.1 34.4 32.0 39.7 14.4 46.6 55.4 45.0 41.6 29.5 26.8 79.8 66.9 85.4 37.7 59.6 32.7 53.8 35.0 30.8 52.4 55.2 34.8 35.0 115.0 48.4 52.5 69.2 40.5 75.3 70.3 60.3 69.3 73.9 56.7 74.2 68.6 70.2 71.4 29.3 PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477266-173488807 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" 180000000 "Plasma membrane, Cytosol" "CAB008663: AB_1620994, HPA006983: AB_1079595" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.96e-1)" "prognostic unfavourable (1.23e-5)" "unprognostic (5.71e-3)" "unprognostic (2.80e-2)" "unprognostic (5.27e-3)" "unprognostic (3.96e-3)" "unprognostic (3.19e-3)" "unprognostic (1.59e-1)" "prognostic unfavourable (9.51e-4)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-3)" 80.0 42.1 32.8 30.8 38.9 21.8 106.3 19.8 32.8 27.2 46.7 37.4 35.8 12.1 30.8 54.1 39.9 40.2 22.3 70.5 29.0 23.9 45.9 116.1 29.2 37.5 34.0 28.2 31.5 39.3 63.9 19.1 36.9 30.3 40.0 56.0 21.3 22.6 35.4 128.0 25.7 20.2 40.5 19.7 23.1 33.2 44.9 24.1 17.4 46.9 68.6 25.7 36.5 46.2 17.2 37.9 14.3 23.9 12.0 25.0 30.6 51.2 15.8 26.2 29.0 101.5 49.6 22.1 104.7 35.7 43.7 31.1 29.7 34.5 33.4 33.5 85.8 29.9 34.2 33.7 35.6 29.3 31.6 22.1 27.0 33.5 57.3 23.1 7.3 41.1 34.2 24.0 33.7 42.8 49.2 6.9 49.6 10.5 15.7 30.5 57.5 97.9 18.8 30.3 34.0 65.5 11.7 12.2 22.6 36.1 42.5 24.0 35.9 32.7 28.8 17.1 19.5 25.8 28.4 10.5 15.4 27.4 20.4 20.1 15.5 13.9 23.9 12.9 17.0 20.6 18.9 17.2 17.6 21.1 29.3 13.6 23.2 25.0 14.3 12.0 17.5 37.9 20.4 30.6 32.8 38.9 19.8 32.8 29.0 23.9 34.0 28.2 30.3 24.1 PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105277565-105403084 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol 1400000 Cytosol "CAB025414: , HPA031388: , HPA031389: , HPA031390: " "unprognostic (3.05e-2)" "unprognostic (9.09e-3)" "unprognostic (2.85e-2)" "unprognostic (5.46e-2)" "unprognostic (3.36e-1)" "prognostic unfavourable (3.33e-4)" "unprognostic (2.63e-3)" "unprognostic (2.39e-1)" "unprognostic (6.78e-2)" "unprognostic (5.81e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-3)" "unprognostic (2.74e-2)" "unprognostic (8.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" 13.0 14.2 10.1 22.2 10.1 10.4 36.2 10.9 24.9 11.9 27.2 5.2 11.2 20.2 13.2 10.9 16.4 10.5 15.0 19.0 8.8 7.1 8.9 14.6 23.9 31.4 8.3 15.4 13.6 18.8 16.1 11.1 15.4 9.7 9.4 33.0 8.9 14.9 11.5 58.0 24.2 19.0 15.3 8.5 11.9 14.0 20.1 8.8 17.4 10.2 18.5 13.3 18.2 21.0 8.3 15.3 7.1 18.7 16.6 16.3 11.2 10.8 13.3 14.2 15.9 33.6 19.9 14.0 14.6 13.7 19.3 20.5 16.9 6.9 13.9 14.4 17.1 16.9 20.9 42.8 22.0 21.0 20.4 18.7 11.2 19.2 13.0 18.8 13.7 18.5 26.1 13.9 35.8 18.0 31.8 24.9 23.3 17.6 12.5 19.1 13.7 13.3 19.4 24.5 9.1 14.4 25.9 18.6 26.5 12.8 21.5 10.2 9.2 30.2 18.1 8.9 12.3 11.1 17.9 7.3 4.8 18.2 15.7 20.5 27.6 4.8 13.6 7.1 16.0 15.4 15.6 8.3 13.7 16.3 15.3 6.8 12.9 15.2 0.7 16.6 18.7 6.5 12.0 11.2 10.1 10.1 10.9 24.9 8.8 7.1 8.3 15.4 9.7 8.8 PREPL KIAA0436 ENSG00000138078 "Prolyl endopeptidase like" Q4J6C6 2 44316281-44361862 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063238 Approved "HPA063238: " "unprognostic (5.60e-3)" "unprognostic (9.81e-2)" "unprognostic (4.51e-2)" "unprognostic (4.65e-3)" "unprognostic (2.22e-1)" "unprognostic (8.53e-2)" "unprognostic (5.98e-3)" "unprognostic (4.38e-3)" "unprognostic (2.27e-1)" "unprognostic (2.72e-2)" "unprognostic (1.52e-2)" "unprognostic (4.67e-2)" "unprognostic (2.33e-2)" "unprognostic (3.79e-1)" "unprognostic (1.87e-1)" "unprognostic (1.76e-1)" "unprognostic (1.75e-1)" 11.5 24.5 32.6 8.2 78.4 2.5 15.0 57.3 75.8 18.1 11.3 18.7 6.0 12.0 22.1 34.2 10.9 16.4 13.4 28.2 51.8 50.2 30.4 9.9 11.4 7.6 28.5 44.0 24.3 11.6 34.9 33.2 9.9 69.4 18.1 14.1 13.0 11.7 16.5 13.7 10.2 12.6 16.3 31.3 10.5 12.1 12.6 21.5 5.2 28.9 7.1 8.2 10.7 10.3 8.8 6.3 4.7 4.8 11.1 12.5 5.8 18.3 14.1 16.3 20.7 26.5 27.8 12.5 20.7 15.7 14.9 12.9 15.3 13.0 23.6 28.7 21.5 15.9 23.5 15.0 28.7 21.6 16.6 16.5 11.3 11.6 19.2 15.6 15.2 17.9 30.0 28.7 23.3 14.3 20.2 34.3 19.9 9.8 17.1 7.6 15.7 16.1 13.5 19.9 16.8 28.5 10.7 28.1 21.8 13.5 14.2 29.9 19.0 12.4 15.0 26.5 15.0 20.7 14.0 18.9 12.4 15.5 31.0 18.6 19.5 4.7 4.5 3.4 8.5 4.8 12.2 8.8 8.1 9.2 6.3 7.4 12.5 9.7 1.3 11.1 4.1 3.1 8.7 5.8 32.6 78.4 57.3 75.8 51.8 50.2 28.5 44.0 69.4 21.5 PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759379-40798374 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles" "Nuclear speckles" "CAB005050: AB_562037, HPA035409: , HPA064946: " "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-2)" 40.6 15.7 9.4 15.9 16.1 29.0 26.2 14.3 17.7 30.2 24.0 19.9 18.9 21.7 23.5 20.9 22.5 20.4 21.3 15.0 10.5 11.7 35.9 40.7 24.8 16.7 12.2 8.5 28.8 20.6 25.3 20.0 16.8 35.7 26.1 22.3 20.0 23.2 17.9 18.5 16.6 32.6 20.7 14.1 25.1 22.1 29.3 11.4 21.4 28.0 20.5 22.9 32.5 17.9 8.4 6.5 15.9 8.9 10.8 12.6 6.5 11.3 11.8 9.5 12.6 23.5 24.5 9.0 19.3 19.8 14.5 13.0 11.1 14.7 6.7 9.0 19.8 9.2 8.7 17.6 27.5 19.6 7.9 13.3 27.3 8.8 19.4 12.6 14.0 22.6 8.6 19.4 20.0 21.4 6.2 19.4 21.6 5.4 11.6 9.9 4.1 14.3 9.8 20.3 9.8 22.3 19.3 8.2 8.3 33.9 22.6 11.5 11.9 10.5 22.9 26.2 14.2 15.1 15.7 7.7 6.0 8.0 16.4 27.4 13.9 14.1 6.6 12.7 10.0 8.1 12.6 8.4 9.4 9.4 6.5 7.7 11.5 10.0 15.9 10.8 8.9 2.0 11.3 6.5 9.4 16.1 14.3 17.7 10.5 11.7 12.2 8.5 35.7 11.4 PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645322-56715335 "Enzymes, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 40.2" "Cell line enhanced" "Detected in many" "HEK 293: 8.5;RPTEC TERT1: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" "Nuclear speckles" "Golgi apparatus" "HPA044540: " "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavourable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavourable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favourable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" 2.4 2.1 3.7 1.2 6.3 0.7 4.1 7.2 8.1 2.2 5.5 1.2 2.4 1.2 3.0 3.2 6.3 3.5 2.6 39.1 4.2 2.9 14.5 1.4 2.0 0.8 2.4 6.2 2.5 2.6 10.4 2.6 1.2 5.0 4.6 2.2 6.0 4.5 3.5 40.2 1.4 2.1 7.2 1.9 1.9 3.2 1.7 0.8 0.0 4.0 12.3 0.8 4.4 2.1 0.2 0.0 1.0 0.1 0.1 0.1 0.0 0.0 3.7 2.0 0.0 0.7 0.5 2.3 1.8 1.4 2.5 4.3 3.8 4.7 0.0 0.6 0.6 0.0 7.8 0.0 7.1 0.0 8.5 0.0 6.9 5.2 0.0 0.0 0.1 0.6 0.0 3.5 0.3 0.8 0.0 0.0 1.0 0.1 0.0 0.0 5.5 5.4 0.0 0.0 0.0 14.0 1.2 2.0 5.4 5.7 0.1 0.0 3.2 0.0 0.0 1.5 2.3 2.7 6.3 0.0 0.0 0.0 4.5 0.0 1.1 0.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 3.7 6.3 7.2 8.1 4.2 2.9 2.4 6.2 5.0 0.8 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved Cytosol 1300000 Cytosol "CAB010361: AB_2268772, HPA071185: " "unprognostic (1.08e-1)" "prognostic favourable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavourable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favourable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 25.6 43.4 19.6 17.8 22.7 9.1 34.1 29.1 39.6 20.6 17.5 16.0 16.2 13.4 19.8 15.6 20.9 18.8 16.4 91.6 20.7 29.4 14.7 34.5 16.5 28.2 21.6 27.5 47.0 15.6 20.8 24.6 15.4 26.9 16.6 16.2 18.4 15.5 24.9 92.4 13.4 14.4 29.0 16.2 28.1 13.9 24.4 11.1 15.2 15.7 26.2 14.8 21.1 17.3 1.7 2.4 8.6 5.3 0.7 1.7 1.2 25.7 15.0 34.0 40.5 30.1 32.0 6.1 27.4 25.4 39.0 35.8 18.2 9.2 11.1 22.2 43.4 16.9 23.9 26.0 37.1 20.3 12.0 20.5 28.3 17.6 25.8 12.6 21.7 30.4 12.5 31.0 10.8 32.8 19.2 29.2 39.8 38.2 28.4 9.5 12.2 33.4 25.7 31.4 25.7 19.0 16.3 26.8 17.1 24.8 15.2 11.3 21.7 12.2 25.4 46.1 12.9 61.6 25.6 20.2 20.7 16.4 30.9 19.2 17.2 0.3 3.4 0.4 1.7 5.3 0.8 1.7 0.9 1.1 2.4 1.3 1.2 1.7 8.6 0.7 4.6 1.6 0.8 1.2 19.6 22.7 29.1 39.6 20.7 29.4 21.6 27.5 26.9 11.1 PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 85.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010363, HPA029754, HPA071185" Approved Approved Cytosol 1500000 Cytosol "CAB010363: AB_2170182, HPA029754: AB_10601491, HPA071185: " "unprognostic (9.38e-2)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "prognostic unfavourable (9.49e-4)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "prognostic favourable (1.89e-6)" "unprognostic (1.22e-1)" "unprognostic (3.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.48e-1)" 7.0 21.5 40.0 10.5 57.0 6.2 8.0 54.7 85.5 9.4 23.6 16.9 3.9 4.8 8.7 17.6 8.1 5.2 11.5 10.1 43.1 52.1 10.6 9.0 6.9 16.2 38.3 33.5 8.3 11.9 12.2 18.3 5.1 35.5 13.8 22.6 4.9 32.9 12.7 3.2 2.6 6.3 12.6 47.7 14.6 14.2 3.6 25.9 25.5 11.1 1.8 15.3 13.5 4.6 13.5 7.1 17.1 5.4 25.9 27.6 22.0 3.1 6.2 9.9 11.9 11.5 10.1 4.6 15.4 11.7 7.8 7.4 0.1 2.8 16.3 10.6 12.0 2.1 4.6 5.0 8.4 15.9 2.5 35.9 8.5 1.2 11.3 14.2 0.8 6.0 2.2 7.6 4.3 36.1 1.1 9.4 12.8 0.5 18.4 7.5 9.8 4.4 14.3 15.5 9.9 19.1 11.1 3.2 12.7 8.5 3.3 9.4 3.0 3.0 32.0 10.9 8.5 11.1 11.6 7.0 8.4 16.5 5.2 15.1 13.6 17.1 2.7 5.8 23.3 3.6 18.7 13.5 17.3 20.6 7.1 10.2 26.4 27.6 1.5 25.9 5.4 4.1 15.9 22.0 40.0 57.0 54.7 58.2 43.1 52.1 38.3 33.5 35.5 25.9 PRKACG PKACg ENSG00000165059 "Protein kinase cAMP-activated catalytic subunit gamma" P22612 9 69012529-69014113 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 27.4" "Cell line enhanced" "Detected in single" "CACO-2: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004530, HPA071185" Supported Approved Cytosol Cytosol "CAB004530: AB_628137, HPA071185: " "unprognostic (2.74e-1)" "unprognostic (3.61e-2)" "unprognostic (7.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRKCA PKCA ENSG00000154229 "Protein kinase C alpha" P17252 17 66302636-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 17 "dendritic cells: 1.4;monocytes: 2.7;T-cells: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Enhanced "Plasma membrane,Cytosol" 1900000 Cytosol "Plasma membrane" "CAB003844: AB_562331, CAB016290: AB_628141, HPA006563: AB_1079626, HPA006564: AB_1079625" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (7.41e-3)" "unprognostic (7.43e-2)" "unprognostic (6.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" "unprognostic (2.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.35e-3)" "unprognostic (8.77e-2)" 4.0 19.6 26.5 9.0 22.8 2.5 3.0 10.8 33.9 7.0 13.8 19.0 3.5 14.6 14.8 6.7 4.7 6.1 10.8 5.8 31.6 15.6 16.7 6.5 6.0 8.4 18.7 15.6 20.4 5.5 1.7 6.0 6.5 17.6 17.2 11.2 7.0 3.1 22.3 6.6 3.8 12.7 13.7 15.0 7.9 7.9 3.7 14.4 0.4 4.5 1.3 5.9 9.5 9.5 0.0 1.4 0.1 2.7 0.1 4.0 1.0 2.3 12.3 2.5 2.6 6.2 15.9 0.3 13.3 8.7 9.6 8.2 1.4 1.5 3.1 3.6 21.4 0.3 1.3 1.5 20.9 5.1 3.0 0.0 7.3 6.4 8.5 3.8 20.9 6.9 0.6 12.0 10.3 8.2 8.0 0.0 14.8 0.7 7.7 2.3 1.0 6.6 1.4 18.8 0.0 3.4 2.0 1.5 8.5 4.4 2.5 0.1 0.3 5.4 24.5 16.7 9.7 10.4 8.3 0.0 0.0 0.3 53.0 0.0 8.2 0.1 0.6 0.0 0.5 0.8 1.5 0.0 2.5 1.2 1.1 0.0 4.0 2.3 0.0 0.1 2.7 1.4 0.5 1.0 26.5 22.8 10.8 28.2 31.6 15.6 18.7 15.6 17.6 14.4 PRKCB "PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835946-24220611 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.2;lymphoid tissue: 31.2" "Cell line enhanced" "Detected in some" "HEL: 40.8;HMC-1: 40.9;K-562: 58.1;THP-1: 18.4;U-937: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol 3400000 Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: , HPA054203: " "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.0 1.9 13.9 20.8 55.6 20.4 1.8 14.1 57.2 4.1 4.7 4.4 0.6 4.9 3.5 1.2 3.2 2.6 3.9 1.5 23.4 7.8 1.8 3.7 5.4 31.0 11.0 20.4 1.2 1.4 0.9 1.4 2.5 8.3 6.2 4.4 3.5 1.9 8.4 1.2 4.6 9.1 5.8 7.3 31.2 3.8 6.4 6.4 24.1 3.9 0.0 27.7 7.6 1.7 23.6 18.5 21.8 14.6 20.1 19.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.8 40.8 1.9 0.0 0.0 5.9 40.9 0.0 0.1 0.0 0.0 0.0 58.1 0.1 0.0 0.0 12.9 12.9 0.3 0.0 12.3 0.1 2.3 0.1 3.6 7.1 0.0 0.0 0.0 0.6 0.0 18.4 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 16.4 0.0 17.5 7.6 14.4 14.5 10.7 6.7 23.6 9.5 17.2 6.2 22.1 7.8 19.0 21.8 20.1 14.6 18.5 6.7 7.5 13.9 55.6 14.1 57.2 23.4 7.8 11.0 20.4 8.3 6.4 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 63.3;THP-1: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 17.7;classical monocyte: 22.9;eosinophil: 17.0;intermediate monocyte: 22.2;myeloid DC: 17.6;neutrophil: 20.7;non-classical monocyte: 15.3;plasmacytoid DC: 8.5" "Group enriched" "Detected in all" 7 "dendritic cells: 17.6;granulocytes: 20.7;monocytes: 22.9" "Group enriched" "Detected in many" 5 "basal ganglia: 124.2;thalamus: 366.1" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" 300000 Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavourable (2.24e-4)" "prognostic favourable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 27.8 33.4 9.4 29.7 11.5 30.3 17.6 5.7 10.7 10.3 27.8 10.1 43.7 21.4 5.5 21.3 18.3 16.1 33.7 11.9 8.3 3.7 16.5 4.5 29.2 24.5 10.2 5.6 8.1 13.4 6.1 5.1 7.5 7.1 17.9 16.1 10.3 14.1 40.7 3.9 17.1 42.9 17.4 10.2 32.1 24.8 9.6 8.0 10.5 26.9 13.4 26.3 22.9 12.7 3.1 17.6 20.7 22.9 2.4 1.5 6.4 7.7 3.0 1.2 2.0 9.0 5.2 11.2 4.7 5.9 5.8 5.7 7.3 7.6 20.0 2.1 10.2 3.5 7.9 11.5 4.7 17.4 6.0 11.1 4.1 7.8 5.7 14.6 25.1 4.1 8.4 5.9 5.5 5.0 2.2 2.9 8.3 19.1 1.6 24.9 3.1 5.5 1.7 3.0 4.7 6.3 16.7 2.0 1.4 3.6 63.3 9.7 5.3 45.2 7.2 2.8 3.6 3.7 4.4 4.4 6.8 10.2 6.7 25.2 5.4 17.7 22.9 17.0 1.5 22.2 1.0 3.1 1.1 1.2 17.6 2.9 0.8 0.7 20.7 2.4 15.3 8.5 1.1 6.4 9.4 11.5 5.7 10.7 8.3 3.7 10.2 5.6 7.1 8.0 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.5" "Cell line enhanced" "Detected in many" "REH: 19.1;TIME: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive B-cell: 5.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA044496, HPA054252" Enhanced Supported Approved Vesicles Vesicles "CAB001948: , HPA044496: , HPA054252: " "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavourable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favourable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favourable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 5.5 7.4 15.3 7.2 14.2 9.3 8.1 28.8 36.5 6.6 5.5 3.8 5.9 3.6 5.6 4.6 4.7 7.6 4.7 7.7 22.5 10.0 12.8 15.5 17.5 6.9 6.0 15.0 4.1 4.2 16.3 6.0 10.4 9.1 3.6 4.7 3.7 3.6 8.6 7.2 3.0 3.7 6.2 4.4 4.9 4.4 7.2 3.7 1.5 6.5 1.2 5.4 5.0 6.5 5.5 2.2 1.7 1.4 0.9 1.3 0.6 5.3 2.0 2.8 2.8 4.3 5.1 2.3 3.8 6.8 3.2 3.4 0.5 5.3 8.1 3.6 3.9 1.3 1.8 2.0 4.5 4.8 3.4 0.0 1.4 1.1 4.9 0.6 2.9 4.5 2.2 4.7 3.4 11.6 1.1 1.9 3.6 2.7 2.6 0.3 1.0 1.0 19.1 13.5 8.6 2.9 3.7 2.0 4.3 1.7 5.7 12.3 4.6 1.9 19.2 6.2 6.5 4.5 3.7 0.0 0.0 6.8 5.1 4.5 6.2 0.0 1.2 1.7 1.0 0.4 1.1 3.6 0.7 0.7 2.2 5.5 1.3 0.4 0.4 0.9 1.4 0.9 0.0 0.6 15.3 14.2 28.8 33.2 22.5 10.0 6.0 15.0 9.1 3.7 PRKCG "MGC57564, PKCC, PKCG, SCA14" ENSG00000126583 "Protein kinase C gamma" P05129 19 53879190-53907652 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 49.9" "Cell line enhanced" "Detected in some" "A549: 5.8;HAP1: 2.7;SH-SY5Y: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013051, HPA047870, HPA054560" Enhanced "CAB013051: AB_2533015, HPA047870: , HPA054560: " "unprognostic (7.14e-2)" "unprognostic (5.42e-2)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.96e-2)" "unprognostic (4.46e-2)" "unprognostic (2.09e-1)" "unprognostic (2.64e-2)" "unprognostic (7.48e-3)" "unprognostic (2.68e-1)" "unprognostic (2.22e-7)" "unprognostic (2.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" 1.0 0.9 28.0 1.1 49.9 2.2 0.9 12.1 39.2 0.9 1.3 1.6 0.0 1.5 1.0 0.9 1.0 1.4 1.0 0.9 49.7 4.4 0.9 0.9 1.0 0.9 2.9 20.8 0.9 3.5 2.1 0.2 0.9 0.7 0.9 1.2 0.0 0.9 1.0 1.0 0.9 1.3 1.1 1.4 0.9 1.8 4.4 2.1 1.3 0.9 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 5.8 1.3 0.0 0.0 0.2 0.1 0.7 0.4 0.1 0.0 1.5 1.5 0.3 1.7 0.0 0.5 2.7 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.0 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.1 1.0 0.5 1.0 0.6 0.1 1.1 0.0 0.0 4.0 1.6 0.2 0.0 1.9 0.0 1.0 0.0 2.0 0.0 0.0 1.7 0.4 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.0 49.9 12.1 28.5 49.7 4.4 2.9 20.8 0.7 2.1 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 29.9;HUVEC TERT2: 39.2;MOLT-4: 26.0;RT4: 16.5;TIME: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "gdT-cell: 30.0;MAIT T-cell: 23.9;memory CD4 T-cell: 23.0;memory CD8 T-cell: 35.3;naive CD4 T-cell: 28.5;naive CD8 T-cell: 27.6;NK-cell: 27.3;T-reg: 18.6" "Group enriched" "Detected in many" 14 "NK-cells: 27.3;T-cells: 35.3" "Group enriched" "Detected in many" 6 "basal ganglia: 25.0;thalamus: 19.5" "Low region specificity" "Detected in many" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: " "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favourable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 17.5 5.4 5.0 21.6 22.0 11.2 14.7 2.8 6.1 13.6 10.3 6.2 6.9 5.1 19.1 7.0 20.1 8.6 12.7 10.1 6.8 4.4 8.1 5.5 24.1 27.6 5.9 2.5 7.1 5.9 8.8 15.5 22.7 7.2 9.8 5.0 9.1 24.7 10.8 9.1 15.9 16.0 10.5 5.7 25.9 6.0 4.3 6.4 54.6 15.1 10.6 34.6 13.2 14.4 0.4 2.2 1.5 0.7 27.3 35.3 17.9 6.2 2.2 0.3 1.7 1.0 0.2 29.9 0.1 0.5 0.3 0.3 0.6 3.7 0.1 4.5 0.0 4.4 0.2 4.8 0.5 0.7 2.8 0.0 0.7 0.2 0.4 0.0 0.9 0.8 5.0 0.2 3.4 39.2 0.0 0.1 2.2 11.5 26.0 0.2 0.5 3.0 2.2 1.1 0.0 0.0 16.5 1.1 1.9 0.7 5.8 3.6 5.7 0.5 25.7 0.7 5.2 0.7 0.3 0.5 0.1 0.2 1.1 0.3 1.2 0.1 0.7 0.5 30.0 0.4 23.9 0.4 23.0 35.3 2.2 0.3 28.5 27.6 1.5 27.3 0.2 0.7 18.6 17.9 5.0 22.0 2.8 6.1 6.8 4.4 5.9 2.5 7.2 6.4 PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222365-170305981 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Cytosol "Microtubules, Cytokinetic bridge" "HPA026574: AB_1855428, HPA038635: " "unprognostic (2.26e-1)" "unprognostic (6.75e-2)" "unprognostic (4.57e-2)" "prognostic unfavourable (3.93e-6)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavourable (3.02e-4)" "unprognostic (2.52e-1)" "unprognostic (7.10e-2)" "unprognostic (1.73e-2)" "prognostic unfavourable (1.22e-4)" "unprognostic (5.32e-3)" "prognostic favourable (3.10e-4)" "unprognostic (1.16e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" 10.3 7.5 11.4 5.9 15.5 2.1 9.5 14.8 16.6 12.5 11.1 7.0 6.0 10.4 13.1 8.4 20.6 15.1 10.5 10.1 9.5 7.7 13.0 6.7 14.8 3.9 5.6 9.4 15.2 7.7 12.4 14.7 9.8 11.0 16.3 12.2 7.3 25.8 12.6 12.7 11.0 11.6 12.5 6.8 6.1 30.2 15.0 5.3 12.6 23.1 8.4 9.9 16.3 13.0 1.9 1.8 1.0 1.3 5.8 4.8 1.4 35.9 9.1 9.2 9.8 8.2 11.4 14.9 9.2 13.7 12.3 13.3 13.3 17.6 11.0 30.5 13.0 16.9 17.3 18.1 21.1 8.0 10.7 10.2 11.6 7.4 13.0 9.2 4.6 10.2 12.7 10.4 16.5 9.5 11.2 9.1 12.3 12.4 13.3 3.6 19.3 10.2 9.6 14.2 18.2 19.3 11.0 14.6 11.9 20.0 26.3 9.0 28.9 6.3 10.1 12.8 9.9 11.9 15.2 15.7 15.1 15.7 9.2 7.2 5.0 0.1 1.3 1.0 2.6 1.2 4.0 1.8 3.6 4.8 1.8 1.9 3.9 2.2 0.7 5.8 1.1 1.8 2.3 1.4 11.4 15.5 14.8 16.6 9.5 7.7 5.6 9.4 11.0 5.3 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 19.7;lymphoid tissue: 32.1;skeletal muscle: 63.4" "Cell line enhanced" "Detected in some" "HEL: 30.9;MOLT-4: 23.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "gdT-cell: 12.7;MAIT T-cell: 9.8;memory CD4 T-cell: 13.5;memory CD8 T-cell: 13.2;naive CD4 T-cell: 10.7;naive CD8 T-cell: 10.0;NK-cell: 6.5;T-reg: 19.7" "Group enriched" "Detected in many" 11 "NK-cells: 6.5;T-cells: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" 200000 "Centriolar satellite" "HPA065279: , HPA073098: " "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavourable (5.27e-4)" "unprognostic (3.51e-2)" 0.9 0.7 3.6 9.4 4.3 3.1 0.8 0.9 5.2 1.3 1.1 7.4 0.1 1.2 1.8 5.4 1.6 2.6 1.3 0.5 4.4 4.0 4.6 0.9 3.3 6.6 4.0 2.2 1.1 7.7 0.3 1.0 0.4 2.7 1.4 1.3 5.4 2.8 1.0 63.4 0.6 2.5 0.8 3.6 3.4 1.4 0.9 4.5 32.1 9.1 7.5 6.8 1.9 0.8 0.0 0.1 1.1 0.2 6.5 19.7 5.2 0.0 2.9 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.2 1.8 0.2 0.0 0.0 0.0 1.8 3.3 0.0 0.0 2.1 30.9 0.0 0.2 0.4 1.5 0.3 0.1 2.0 0.1 0.1 0.3 6.7 0.0 0.0 0.0 23.2 4.3 3.2 0.0 4.5 0.7 0.0 6.5 1.6 0.2 1.2 0.0 0.0 0.0 0.0 3.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.1 0.1 0.1 12.7 0.2 9.8 0.0 13.5 13.2 0.1 0.0 10.7 10.0 0.8 6.5 0.0 0.0 19.7 5.2 3.6 4.3 0.9 5.2 4.4 4.0 4.0 2.2 2.7 4.5 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050470-2185395 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.6;placenta: 93.0" "Cell line enhanced" "Detected in many" "BEWO: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "eosinophil: 15.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favourable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.2 7.8 15.9 3.0 31.8 1.4 3.9 39.8 43.6 3.2 8.6 17.1 2.3 20.0 1.7 5.5 10.1 6.5 3.1 6.4 15.5 6.4 11.3 6.8 22.3 5.0 12.2 23.6 1.9 8.5 9.8 12.0 93.0 27.3 5.8 7.5 2.6 7.0 3.0 0.4 8.8 18.4 1.2 8.4 6.9 6.1 17.5 13.5 0.6 14.1 0.9 5.0 4.0 4.6 0.4 0.3 15.0 0.3 0.8 2.6 0.3 7.5 4.8 1.7 8.9 0.0 0.0 23.5 0.5 0.2 5.6 0.3 12.1 16.4 0.0 14.9 1.9 13.2 10.1 12.5 4.0 0.5 11.2 0.0 7.7 16.1 1.6 0.0 5.8 0.3 7.5 0.0 4.3 0.0 3.3 0.1 0.1 9.2 0.4 0.0 3.4 11.7 0.0 0.0 2.6 9.6 7.9 12.3 9.9 6.1 13.7 2.6 9.6 2.0 0.0 0.0 7.1 0.1 0.0 3.5 0.6 0.1 0.6 0.1 8.5 0.3 0.0 15.0 0.6 0.3 2.6 0.3 1.0 0.6 0.0 0.4 0.8 0.4 1.2 0.8 0.0 0.3 0.8 0.3 15.9 31.8 39.8 43.6 15.5 6.4 12.2 23.6 27.3 13.5 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 17.8;fHDF/TERT166: 19.0;HSkMC: 17.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favourable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavourable (2.91e-4)" "unprognostic (3.89e-1)" 7.4 10.6 8.0 5.3 9.7 0.7 19.0 4.9 8.9 5.1 8.7 5.1 24.1 3.1 8.3 9.0 3.5 6.8 9.0 6.3 9.8 5.9 15.1 2.3 14.9 1.6 5.6 6.6 15.7 7.3 35.7 9.2 4.5 10.8 20.1 3.5 4.9 3.5 24.4 3.1 2.7 3.5 19.7 16.4 2.4 4.8 16.1 8.6 0.5 8.2 2.9 1.8 14.1 12.2 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.6 4.0 17.8 16.7 0.1 12.1 9.3 12.4 6.7 0.0 0.5 0.0 1.2 19.0 0.1 5.9 1.4 6.8 0.0 4.1 0.0 0.1 0.4 9.0 0.0 0.1 17.7 0.6 0.8 1.4 2.5 1.2 0.4 11.6 1.3 0.0 0.0 2.5 6.2 0.0 7.0 3.2 13.2 5.6 3.6 7.1 2.1 0.0 4.7 0.0 0.1 6.3 11.7 4.8 1.0 3.5 0.0 0.0 0.0 3.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 8.0 9.7 4.9 8.9 9.8 5.9 5.6 6.6 10.8 8.6 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favourable (9.15e-4)" 17.1 7.6 7.0 25.8 6.5 18.1 18.0 2.5 6.8 16.8 13.7 5.8 18.7 13.7 14.8 16.5 23.4 15.6 17.4 7.4 6.3 3.1 13.2 9.1 21.3 24.8 7.5 2.7 17.0 12.5 10.3 17.2 20.1 6.6 14.8 7.7 11.9 15.6 21.5 7.5 26.8 19.8 11.7 6.8 34.8 15.2 6.6 7.2 41.5 18.7 10.5 33.0 17.4 37.5 6.6 0.4 7.3 1.0 2.9 6.1 1.9 8.6 13.4 5.3 6.5 4.4 3.6 6.8 4.5 7.1 9.4 10.3 7.4 8.5 10.1 7.9 6.0 12.9 4.7 12.0 2.9 8.6 7.0 10.6 4.2 3.9 5.8 7.7 15.7 4.3 5.8 5.4 4.6 16.5 6.8 14.6 3.9 9.1 14.8 25.0 4.5 6.8 9.7 2.5 16.3 5.8 12.9 3.4 10.8 8.4 7.0 1.8 5.6 3.1 7.8 4.0 8.0 3.4 3.6 14.3 56.9 5.0 4.2 6.4 4.2 0.9 1.0 3.4 5.6 0.9 4.9 6.1 5.7 6.1 0.4 6.6 5.1 4.9 7.3 2.9 0.7 0.0 4.0 1.9 7.0 6.5 2.5 6.8 6.3 3.1 7.5 2.7 6.6 7.2 PRKD3 "EPK2, PRKCN" ENSG00000115825 "Protein kinase D3" O94806 2 37250502-37324808 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029529 Uncertain Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA029529: AB_10602082" "unprognostic (1.39e-1)" "unprognostic (7.34e-2)" "prognostic favourable (4.84e-4)" "unprognostic (1.23e-2)" "unprognostic (5.61e-2)" "unprognostic (2.08e-1)" "prognostic unfavourable (3.47e-4)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (2.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.81e-1)" "unprognostic (7.62e-3)" "unprognostic (2.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" 16.1 22.1 9.5 20.7 10.7 5.3 35.1 4.8 9.2 17.2 18.0 7.2 7.2 6.0 19.2 16.0 9.8 11.3 10.0 11.6 12.7 6.1 9.9 8.4 20.4 22.3 11.4 3.7 15.0 7.6 12.9 20.7 11.1 10.3 14.4 8.3 27.8 11.1 13.3 19.1 11.5 12.1 16.5 15.4 22.0 10.5 16.8 10.8 16.2 11.8 9.3 21.2 12.4 17.7 16.4 8.2 5.7 8.3 6.3 11.5 3.4 12.6 5.4 14.3 11.8 10.9 18.4 10.5 8.2 15.3 9.3 9.5 8.6 4.5 18.6 6.9 12.3 5.0 9.7 10.1 12.6 24.0 14.2 12.2 8.3 5.8 4.5 8.7 7.5 8.6 5.2 14.7 9.7 16.5 10.2 22.9 10.8 2.1 3.8 6.8 15.1 5.2 12.8 22.6 15.9 6.2 14.3 10.8 28.0 7.9 4.5 48.2 4.9 8.0 15.9 26.7 13.9 10.6 9.2 26.2 48.5 21.7 9.3 3.7 16.0 5.7 8.3 5.5 10.5 6.6 9.1 12.4 8.8 8.4 7.8 16.4 10.4 11.5 1.5 6.3 3.3 8.2 4.1 3.4 9.5 10.7 4.8 9.2 12.7 6.1 11.4 3.7 10.3 10.8 PRKDC "DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7" ENSG00000253729 "Protein kinase, DNA-activated, catalytic polypeptide" P78527 8 47773108-47960183 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005167, HPA035174" Supported Enhanced Nucleoplasm 1100000 Nucleoplasm "CAB005167: AB_2172845, HPA035174: " "unprognostic (3.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.56e-2)" "prognostic unfavourable (1.03e-4)" "unprognostic (8.95e-2)" "unprognostic (1.34e-1)" "unprognostic (7.70e-3)" "unprognostic (5.74e-2)" "unprognostic (1.12e-2)" "unprognostic (1.60e-2)" "unprognostic (7.76e-3)" "unprognostic (7.77e-2)" "unprognostic (2.84e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-1)" "unprognostic (6.76e-3)" "unprognostic (2.15e-2)" 21.3 20.5 16.0 22.3 22.0 27.4 30.2 16.5 23.1 19.6 20.6 17.3 18.1 12.0 26.2 14.5 27.4 24.4 13.0 21.1 20.8 15.2 16.7 18.4 17.0 33.6 16.6 18.2 24.6 23.8 33.4 29.4 20.5 17.3 17.9 20.3 17.8 17.9 17.8 34.0 23.9 18.4 27.0 20.3 24.4 19.1 20.5 15.9 44.4 20.8 15.9 27.9 21.3 19.1 17.0 13.9 7.1 11.5 11.5 11.3 2.3 32.4 27.8 27.1 25.7 16.9 17.9 11.5 13.8 13.6 19.5 19.2 18.1 10.7 31.0 12.0 16.9 18.5 35.8 18.9 30.6 6.8 22.2 60.9 25.0 22.2 7.3 23.1 12.7 12.9 6.2 30.7 32.2 20.0 40.5 13.1 21.4 15.2 32.6 19.1 29.8 8.4 16.0 21.3 10.9 9.8 28.0 13.6 17.3 42.6 13.9 13.4 19.9 16.0 23.2 25.5 21.7 20.1 27.7 11.5 14.6 44.6 14.4 26.3 20.6 6.7 8.1 3.5 8.7 6.3 10.9 12.6 10.8 8.8 5.9 17.0 11.3 10.3 7.1 11.5 11.5 13.9 7.4 2.3 16.0 22.0 16.5 23.1 20.8 15.2 16.6 18.2 17.3 15.9 PRKG1 "PGK, PKG, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase, cGMP-dependent, type I" Q13976 10 50990891-52298350 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 11.3;BJ hTERT+: 15.5;fHDF/TERT166: 12.9;U-138 MG: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21 "basophil: 8.0" "Lineage enriched" "Detected in single" 24 "granulocytes: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol 33000 "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" 8.0 10.9 5.2 6.6 7.3 0.8 6.9 2.8 5.4 19.2 14.4 2.1 6.8 2.9 22.8 10.7 6.0 9.9 12.6 14.8 7.0 4.9 4.4 2.1 19.5 2.6 3.1 4.8 8.9 2.6 13.7 8.4 11.0 4.6 9.5 6.2 6.2 6.4 9.4 24.9 2.8 5.3 28.2 2.7 2.7 5.9 5.0 3.1 0.2 9.2 12.7 1.2 13.4 15.8 0.1 0.1 8.0 0.1 0.3 0.0 0.1 0.0 0.1 1.4 11.3 5.4 5.2 0.0 4.9 15.5 1.6 2.3 0.1 0.7 0.2 0.0 12.9 0.1 0.0 0.0 1.4 0.0 4.2 0.8 0.3 0.0 4.7 0.0 0.0 6.6 0.0 4.1 0.1 0.0 0.0 0.1 4.3 0.1 0.0 0.0 3.2 1.9 0.0 3.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.1 0.0 0.0 9.5 1.7 4.8 2.9 1.2 0.5 0.0 8.4 0.0 2.0 8.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.1 0.0 0.1 5.2 7.3 2.8 5.4 7.0 4.9 3.1 4.8 4.6 3.1 PRKG2 "cGKII, PRKGR2" ENSG00000138669 "Protein kinase, cGMP-dependent, type II" Q13237 4 81087370-81215117 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.3" "Cell line enhanced" "Detected in some" "ASC diff: 5.1;ASC TERT1: 3.9;HEL: 20.3;hTCEpi: 4.0;SCLC-21H: 6.3" "Cancer enhanced" "Detected in some" "melanoma: 4.1" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.0;MAIT T-cell: 2.2" "Group enriched" "Detected in many" 4 "granulocytes: 2.0;T-cells: 2.2" "Low region specificity" "Detected in many" "HPA007386, CAB018739" Approved "CAB018739: AB_2284387, HPA007386: AB_1079678" "unprognostic (6.14e-2)" "unprognostic (2.77e-1)" "unprognostic (2.14e-1)" "unprognostic (5.01e-4)" "unprognostic (4.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.13e-1)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.58e-1)" "unprognostic (4.00e-3)" "unprognostic (1.06e-1)" 4.7 0.4 5.2 0.4 2.9 0.6 2.2 0.8 5.3 1.4 7.7 1.2 0.7 12.2 0.6 0.6 3.8 0.6 0.4 6.3 2.9 3.3 0.7 0.3 4.3 0.3 2.5 1.9 0.3 1.8 0.0 12.1 0.2 9.3 12.7 3.8 1.4 0.8 4.6 0.3 2.1 34.3 0.7 1.3 0.3 1.3 1.7 2.4 0.0 1.3 0.0 0.6 1.2 1.3 0.4 0.0 2.0 0.0 0.4 2.2 0.4 0.1 0.3 0.1 0.0 5.1 3.9 0.0 0.2 0.0 0.0 0.0 0.4 2.3 0.0 0.2 0.9 0.1 0.3 1.5 0.0 0.4 0.0 20.3 0.6 0.0 0.0 0.0 0.0 0.5 4.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.1 0.0 0.8 6.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 2.2 0.2 0.5 0.3 0.0 0.4 0.8 0.9 0.0 0.4 0.0 0.0 0.0 0.4 5.2 2.9 0.8 5.3 2.9 3.3 2.5 1.9 9.3 2.4 PRKN "AR-JP, PARK2, parkin, PDJ" ENSG00000185345 "Parkin RBR E3 ubiquitin protein ligase" O60260 6 161347420-162727771 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.8" "Cell line enhanced" "Detected in some" "AN3-CA: 3.6;HEL: 9.0;Karpas-707: 5.7;RPMI-8226: 5.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016257, HPA036012" Enhanced Supported "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB016257: AB_628104, HPA036012: " "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.69e-3)" "unprognostic (9.85e-2)" "unprognostic (5.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-3)" "unprognostic (8.16e-2)" "prognostic favourable (6.75e-12)" "unprognostic (9.93e-2)" "unprognostic (1.51e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-1)" 6.8 7.1 7.9 2.3 12.2 1.5 4.2 7.2 13.4 5.3 4.3 6.3 4.6 2.8 7.8 4.4 6.1 3.4 4.3 17.7 9.2 6.2 17.4 3.6 2.6 3.0 5.8 5.2 6.4 3.0 5.6 8.6 2.0 5.5 4.0 2.4 8.3 3.5 4.8 41.8 4.0 3.3 6.6 5.9 2.7 3.5 10.3 6.8 0.6 3.8 4.7 2.7 4.9 2.1 4.6 1.2 4.2 0.8 1.8 4.6 1.3 0.0 0.3 1.2 3.6 0.9 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 0.0 0.2 0.2 0.0 0.4 0.6 9.0 0.2 0.0 0.8 0.2 0.1 3.1 0.1 0.0 0.5 0.0 0.4 5.7 0.9 0.5 0.1 0.1 0.2 0.8 0.0 0.0 5.7 0.6 0.1 0.9 2.5 0.0 0.0 0.3 0.0 0.6 0.0 0.1 0.3 0.1 0.3 0.8 0.1 0.0 0.1 0.1 2.2 2.8 0.8 4.2 2.1 0.5 3.5 1.5 2.0 2.2 1.2 4.6 4.4 4.6 1.5 1.8 0.4 0.3 0.2 1.3 7.9 12.2 7.2 11.7 9.2 6.2 5.8 5.2 5.5 6.8 PRKX PKX1 ENSG00000183943 "Protein kinase, X-linked" P51817 X 3604370-3713608 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 38.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015324 Supported Supported Nucleoplasm Nucleoplasm "HPA015324: AB_1855715" "unprognostic (1.07e-1)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.63e-1)" "unprognostic (2.45e-1)" "unprognostic (3.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.33e-2)" "unprognostic (4.14e-1)" "unprognostic (1.68e-1)" "unprognostic (2.68e-1)" "unprognostic (2.92e-1)" "unprognostic (1.07e-3)" "unprognostic (2.15e-2)" "unprognostic (9.91e-2)" "unprognostic (2.52e-1)" "unprognostic (1.70e-2)" 4.3 1.3 12.3 7.5 15.8 5.4 11.2 4.4 12.3 6.9 5.2 5.4 11.5 4.1 7.3 8.4 13.6 16.5 3.9 4.0 14.0 7.4 14.2 2.0 8.4 9.5 27.9 5.6 4.8 4.1 3.2 2.3 6.6 22.7 3.7 5.2 3.1 6.5 5.3 1.6 9.9 6.0 3.0 17.6 10.0 3.1 6.1 22.7 6.1 28.8 3.2 8.0 3.7 11.2 2.5 2.8 12.2 4.1 3.3 3.8 1.7 4.5 4.2 11.6 8.6 2.2 3.0 10.6 2.7 1.0 1.3 1.8 6.2 3.1 0.4 2.7 2.1 3.1 10.8 8.1 2.3 5.0 7.5 5.0 3.2 0.1 2.3 6.4 38.9 2.0 8.7 1.4 5.4 13.1 5.8 6.5 4.4 3.9 7.3 5.8 7.7 4.8 13.7 11.1 8.5 10.7 3.8 7.8 5.0 2.8 1.8 2.7 1.4 5.1 7.1 1.2 2.0 1.9 1.8 0.1 0.3 5.8 0.7 5.8 3.0 12.2 3.1 1.8 3.5 3.3 3.8 2.5 3.7 3.3 2.3 2.4 3.1 3.3 0.8 3.3 4.1 2.8 2.5 1.7 12.3 15.8 4.4 12.3 14.0 7.4 27.9 5.6 22.7 22.7 PRMT1 "ANM1, HCP1, HRMT1L2" ENSG00000126457 "Protein arginine methyltransferase 1" Q99873 19 49675786-49689029 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022550, HPA069769, HPA072136" Supported Supported Nucleoplasm Nucleoplasm "CAB022550: , HPA069769: , HPA072136: " "unprognostic (1.88e-2)" "unprognostic (1.28e-2)" "unprognostic (3.00e-2)" "unprognostic (3.84e-1)" "unprognostic (4.13e-2)" "unprognostic (3.33e-2)" "prognostic unfavourable (8.04e-5)" "unprognostic (3.43e-2)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.05e-1)" "unprognostic (7.19e-3)" "unprognostic (2.21e-1)" "unprognostic (3.66e-2)" "unprognostic (4.73e-2)" "unprognostic (1.10e-2)" 21.3 31.5 27.4 28.1 29.7 21.8 22.0 29.4 35.9 31.8 25.5 26.9 27.8 21.4 36.0 22.5 28.9 45.4 24.5 56.4 25.2 28.6 23.4 20.8 22.0 34.9 32.0 23.8 43.4 35.0 20.0 31.7 27.9 25.6 33.3 18.4 34.1 20.9 31.5 83.8 21.9 19.8 38.3 20.9 33.3 20.3 24.9 28.0 25.0 32.9 31.3 32.0 29.8 23.8 51.9 41.2 9.2 23.6 38.7 35.5 31.8 37.9 86.9 60.3 72.7 16.4 18.6 31.8 24.4 42.7 70.6 60.8 64.8 30.3 62.5 18.2 28.6 28.1 50.8 51.6 30.9 48.5 87.2 45.6 23.9 70.3 40.1 54.8 32.8 26.0 25.7 39.5 56.9 41.7 47.9 44.4 27.4 57.4 70.7 67.8 63.6 56.6 50.3 48.7 57.0 39.7 80.2 67.3 52.4 28.1 29.2 14.9 22.1 32.3 25.9 41.6 40.4 19.0 58.1 42.8 64.4 61.7 25.5 39.7 43.5 5.8 20.2 9.2 28.6 23.6 35.5 51.9 26.6 30.5 34.2 41.9 29.9 29.1 3.9 38.7 17.1 41.2 24.2 31.8 27.4 29.7 29.4 35.9 25.2 28.6 32.0 23.8 25.6 28.0 PRMT2 "HRMT1L1, MGC111373" ENSG00000160310 "Protein arginine methyltransferase 2" P55345 21 46635167-46665124 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018976, HPA029591" Uncertain Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA018976: AB_1855719, HPA029591: AB_10601250" "unprognostic (1.82e-1)" "unprognostic (2.96e-1)" "unprognostic (8.61e-3)" "unprognostic (1.74e-1)" "unprognostic (1.08e-1)" "unprognostic (1.58e-2)" "unprognostic (1.29e-3)" "unprognostic (1.34e-1)" "unprognostic (2.23e-1)" "unprognostic (6.78e-2)" "unprognostic (4.34e-3)" "unprognostic (1.72e-1)" "unprognostic (4.62e-3)" "unprognostic (8.76e-3)" "unprognostic (2.86e-2)" "unprognostic (1.91e-3)" "unprognostic (2.23e-1)" 19.9 14.7 37.1 21.8 43.6 18.7 28.4 21.4 37.2 25.5 25.2 35.4 12.0 14.7 24.5 15.9 30.7 27.1 23.4 29.4 37.4 53.1 19.9 8.5 21.7 28.7 44.8 32.2 48.5 15.1 19.9 20.1 26.2 44.9 22.0 17.1 20.6 21.0 28.0 9.5 28.1 20.0 28.5 69.6 25.6 17.4 10.1 40.3 13.8 20.1 7.4 28.3 23.1 26.0 18.9 27.6 64.2 26.1 50.8 60.2 41.6 22.7 19.5 39.5 14.7 28.8 28.2 9.7 21.5 24.2 24.4 22.3 27.4 18.6 13.4 27.3 38.3 6.7 18.4 27.1 14.2 33.4 17.7 34.7 16.5 20.4 13.9 10.3 16.5 17.4 27.0 29.6 21.2 35.2 22.0 25.2 37.3 25.4 14.8 19.4 21.6 23.0 19.1 10.0 8.8 19.0 19.5 28.6 17.8 22.7 10.4 41.0 14.0 10.7 31.8 23.9 16.4 12.6 14.1 6.7 6.1 8.5 21.9 28.1 34.4 44.2 19.6 64.2 60.2 26.0 43.6 18.9 40.5 51.0 27.6 16.7 49.9 56.9 26.3 50.8 26.1 23.8 29.0 41.6 37.1 43.6 21.4 37.2 37.4 53.1 44.8 32.2 44.9 40.3 PRMT5 "HRMT1L5, SKB1, SKB1Hs" ENSG00000100462 "Protein arginine methyltransferase 5" O14744 14 22920511-22929585 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005525, CAB012459, HPA064708" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB012459: , HPA005525: AB_1079679, HPA064708: " "unprognostic (8.34e-2)" "unprognostic (5.14e-3)" "unprognostic (1.19e-2)" "unprognostic (2.19e-1)" "unprognostic (4.56e-3)" "prognostic unfavourable (1.82e-4)" "prognostic unfavourable (4.77e-5)" "unprognostic (3.64e-2)" "unprognostic (6.80e-2)" "unprognostic (1.48e-1)" "prognostic unfavourable (2.61e-4)" "unprognostic (4.69e-2)" "unprognostic (1.99e-3)" "unprognostic (1.21e-1)" "unprognostic (7.04e-2)" "unprognostic (6.28e-2)" "prognostic unfavourable (1.04e-4)" 17.0 21.6 18.3 17.8 22.8 12.0 21.2 18.4 24.9 20.3 25.0 18.1 24.9 16.1 24.9 19.6 33.1 28.0 16.6 22.3 15.3 13.2 25.7 22.2 15.8 15.6 17.2 15.2 30.2 30.9 30.8 17.4 24.3 15.9 21.1 22.6 16.9 19.0 21.7 42.0 21.7 14.5 22.2 13.4 17.9 19.5 22.1 17.3 22.7 30.9 19.6 22.1 20.8 22.0 17.6 23.8 4.3 17.6 9.8 15.6 15.5 40.0 38.7 28.0 27.7 13.3 15.2 30.5 27.6 20.5 42.9 36.4 35.4 37.3 39.1 22.6 20.3 32.0 55.4 46.4 49.6 25.1 26.8 24.3 26.1 54.4 25.6 51.0 21.2 15.0 24.8 33.2 60.6 20.3 34.4 21.4 22.1 36.2 36.4 22.8 25.0 49.0 43.1 34.0 28.4 20.8 27.5 30.2 19.8 30.1 32.4 14.1 21.8 19.3 19.0 18.2 26.0 25.9 35.1 29.4 62.6 52.0 11.5 24.8 28.4 1.7 16.8 0.2 8.2 17.6 13.4 17.6 11.3 13.5 23.8 15.5 15.6 12.5 4.3 9.8 13.2 14.1 9.4 15.5 18.3 22.8 18.4 24.9 15.3 13.2 17.2 15.2 15.9 17.3 PRMT6 "FLJ10559, HRMT1L6" ENSG00000198890 "Protein arginine methyltransferase 6" Q96LA8 1 107056679-107059294 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "MCF7: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059424 Approved Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA059424: " "unprognostic (5.17e-3)" "unprognostic (1.48e-1)" "unprognostic (1.47e-2)" "prognostic unfavourable (3.05e-4)" "unprognostic (2.68e-1)" "unprognostic (2.55e-1)" "unprognostic (1.36e-3)" "unprognostic (2.13e-2)" "unprognostic (9.72e-2)" "unprognostic (2.53e-2)" "unprognostic (1.42e-1)" "unprognostic (2.63e-1)" "unprognostic (3.15e-2)" "unprognostic (1.03e-1)" "unprognostic (8.34e-2)" "unprognostic (1.01e-1)" "unprognostic (1.73e-3)" 6.6 16.1 14.4 10.5 13.4 4.6 10.8 12.6 13.9 8.9 10.3 11.5 10.4 8.1 9.7 11.3 10.9 12.2 9.8 5.0 11.8 16.2 16.7 16.3 5.9 11.5 12.2 14.1 12.3 16.8 15.0 13.8 9.6 13.2 11.8 9.7 12.6 8.3 11.4 2.1 7.6 9.3 8.0 13.6 11.5 9.5 9.4 10.6 18.2 9.5 3.4 11.1 10.1 7.3 9.7 14.7 1.8 10.1 14.6 10.9 7.6 3.5 0.0 7.1 3.1 4.7 5.2 1.9 4.8 3.6 4.7 4.8 4.6 2.5 8.8 6.7 4.4 5.1 6.5 7.1 3.7 0.0 6.9 5.3 10.0 6.6 4.7 10.9 3.3 4.9 3.9 4.2 4.3 4.0 7.1 1.3 4.2 81.7 6.4 3.8 3.0 6.7 8.1 15.5 3.3 11.3 7.3 13.3 16.2 6.5 9.5 3.1 6.6 8.2 4.6 3.5 7.1 7.2 7.1 1.5 1.0 1.5 5.1 5.1 2.8 1.8 8.9 1.6 7.5 10.1 8.4 6.9 7.6 6.8 11.9 9.7 10.9 10.9 0.5 14.6 9.2 14.7 7.8 7.6 14.4 13.4 12.6 13.9 11.8 16.2 12.2 14.1 13.2 10.6 PRMT7 "FLJ10640, KIAA1933" ENSG00000132600 "Protein arginine methyltransferase 7" Q9NVM4 16 68310974-68358563 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044241 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" Nucleoplasm "Nucleoli fibrillar center" "HPA044241: " "unprognostic (9.33e-2)" "unprognostic (5.33e-2)" "unprognostic (1.52e-1)" "prognostic favourable (2.31e-5)" "unprognostic (2.92e-2)" "unprognostic (1.95e-1)" "unprognostic (4.12e-2)" "unprognostic (1.22e-1)" "unprognostic (3.74e-1)" "unprognostic (1.19e-1)" "unprognostic (4.74e-3)" "unprognostic (3.09e-2)" "unprognostic (7.72e-2)" "unprognostic (1.75e-1)" "unprognostic (9.23e-2)" "unprognostic (3.57e-1)" "unprognostic (1.31e-1)" 14.8 14.4 15.6 12.7 22.0 11.1 12.9 29.4 20.5 11.4 11.7 20.2 13.9 7.0 18.9 11.9 12.7 18.1 9.3 23.1 14.4 13.1 9.5 12.2 9.7 17.0 11.2 18.7 21.9 14.8 12.0 14.0 11.4 13.3 12.8 7.6 20.8 17.3 16.2 34.0 16.9 9.9 18.5 11.6 12.4 9.9 17.0 13.1 24.4 11.1 12.0 14.9 13.3 10.4 10.8 26.2 9.9 8.5 18.6 18.1 11.5 10.1 16.5 7.8 19.7 7.5 7.1 26.3 10.2 5.5 12.9 10.7 41.6 10.2 21.6 17.1 8.6 13.2 11.1 10.3 7.1 7.7 16.7 6.4 18.5 18.8 5.5 11.8 10.0 7.8 4.4 10.6 10.0 7.7 15.1 1.2 7.0 17.0 14.5 18.2 12.9 11.2 19.5 11.5 14.6 6.0 9.3 10.8 8.4 34.0 8.6 6.9 14.3 11.7 9.2 9.2 8.1 10.9 9.0 6.6 12.3 22.1 11.6 12.6 9.4 9.9 7.0 5.9 15.8 8.5 18.1 10.1 10.6 13.9 10.2 10.8 16.1 14.1 0.8 18.6 7.7 26.2 11.7 11.5 15.6 22.0 29.4 20.5 14.4 13.1 11.2 18.7 13.3 13.1 PRMT9 "FLJ46629, PRMT10" ENSG00000164169 "Protein arginine methyltransferase 9" Q6P2P2 4 147637785-147684230 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036844, HPA042537" Uncertain Approved Nucleoplasm,Microtubules,Cytosol Microtubules "Nucleoplasm, Cytosol" "HPA036844: AB_10672341, HPA042537: " "unprognostic (2.17e-1)" "unprognostic (1.46e-2)" "unprognostic (4.65e-3)" "unprognostic (2.35e-1)" "unprognostic (8.46e-3)" "unprognostic (1.10e-1)" "unprognostic (1.35e-1)" "unprognostic (1.55e-2)" "unprognostic (4.14e-2)" "unprognostic (7.29e-2)" "unprognostic (2.11e-2)" "unprognostic (2.33e-1)" "prognostic favourable (3.58e-7)" "unprognostic (1.72e-1)" "unprognostic (4.52e-2)" "unprognostic (1.54e-2)" "unprognostic (1.30e-2)" 6.0 17.2 6.0 5.2 8.6 12.4 6.9 8.0 8.9 5.6 4.5 4.2 7.9 2.5 8.6 7.6 5.0 7.5 8.4 6.5 5.6 5.0 7.5 5.8 7.6 5.3 5.8 5.3 22.6 7.2 16.3 10.0 5.0 7.1 6.0 4.5 9.8 5.8 11.3 6.7 5.6 4.3 6.1 4.6 4.5 5.9 11.2 3.9 11.6 15.8 2.8 5.4 5.5 5.2 9.6 6.0 10.8 6.1 5.1 10.4 2.7 3.5 2.3 5.6 4.3 4.4 7.4 4.9 3.9 6.2 5.9 6.3 1.8 3.9 12.1 1.8 3.3 2.4 6.5 3.3 8.2 4.4 3.8 6.7 4.4 3.0 3.3 9.7 3.7 5.1 3.5 3.6 3.2 4.9 6.5 7.0 5.0 2.0 8.2 3.8 2.9 4.2 5.6 4.8 4.4 4.8 2.8 3.5 5.3 6.2 4.9 3.2 2.1 2.1 4.2 3.8 3.1 4.2 4.2 8.0 6.4 7.9 4.3 6.0 2.8 7.4 6.0 10.8 6.7 6.1 6.5 9.5 8.1 8.2 4.0 9.6 10.4 9.0 4.2 5.1 4.4 6.0 6.8 2.7 6.0 8.6 8.0 8.9 5.6 5.0 5.8 5.3 7.1 3.9 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429246 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 137.5" "Cell line enriched" "Detected in some" 16 "Hep G2: 57.5" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 9 "plasmacytoid DC: 29.2" "Lineage enriched" "Detected in many" 9 "dendritic cells: 29.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005550, CAB016721, CAB016792" Supported "Secreted to blood" 6400000000 "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.2 4.2 137.5 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.4 29.2 3.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.5 0.0 0.3 0.0 3.6 0.0 0.1 0.0 0.0 0.0 0.0 2.7 57.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 29.2 0.0 0.1 0.4 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.4 0.0 PRODH "HSPOX2, PIG6, PRODH1, PRODH2, TP53I6" ENSG00000100033 "Proline dehydrogenase 1" O43272 22 18912777-18936553 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease mutation, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 48.9" "Cell line enriched" "Detected in some" 8 "RPTEC TERT1: 28.8" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" HPA020361 Approved "HPA020361: AB_10963116" "unprognostic (2.46e-2)" "prognostic favourable (1.54e-4)" "unprognostic (1.40e-1)" "unprognostic (3.70e-2)" "unprognostic (3.80e-2)" "unprognostic (1.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-2)" "unprognostic (2.49e-2)" "unprognostic (6.56e-2)" "unprognostic (3.12e-2)" "unprognostic (1.61e-2)" "unprognostic (7.44e-2)" "unprognostic (1.07e-1)" "unprognostic (1.21e-1)" "unprognostic (5.34e-2)" "unprognostic (3.94e-2)" 3.8 2.3 20.8 2.8 19.3 2.0 3.3 9.8 21.3 2.0 3.5 16.2 0.1 13.8 2.3 2.2 8.8 2.4 2.2 4.6 22.2 10.8 9.9 6.6 8.6 2.3 14.9 21.8 2.4 2.2 1.9 1.5 2.4 13.5 2.6 2.6 7.4 2.1 2.4 15.5 13.0 48.9 1.9 12.6 2.2 2.1 3.5 9.8 0.1 4.3 4.1 3.7 2.1 2.3 0.4 0.4 0.0 0.0 1.0 0.3 0.0 0.0 0.6 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 0.0 2.1 2.9 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 3.4 0.0 0.0 0.0 0.3 28.8 0.6 0.1 0.2 0.6 0.9 0.2 1.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 20.8 19.3 9.8 21.3 22.2 10.8 14.9 21.8 13.5 9.8 PRODH2 HSPOX1 ENSG00000250799 "Proline dehydrogenase 2" Q9UF12 19 35799988-35813299 "Enzymes, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 29 "kidney: 51.2;liver: 49.3" "Cell line enriched" "Detected in some" 18 "Hep G2: 25.9" "Group enriched" "Detected in some" 50 "liver cancer: 28.1;renal cancer: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA051287 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA051287: " "unprognostic (2.58e-1)" "unprognostic (3.41e-3)" "unprognostic (2.75e-2)" "unprognostic (7.03e-2)" "unprognostic (1.73e-1)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 1.7 0.1 0.0 0.3 0.1 0.1 0.0 51.2 49.3 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PROZ PZ ENSG00000126231 "Protein Z, vitamin K dependent plasma glycoprotein" P22891 13 113158654-113172383 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 45.0" "Cell line enhanced" "Detected in some" "HaCaT: 4.8;Hep G2: 7.6" "Cancer enriched" "Detected in single" 27 "liver cancer: 12.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.7;T-reg: 1.5" "Group enriched" "Detected in many" 12 "monocytes: 2.7;T-cells: 1.5" "Not detected" "Not detected" HPA052006 Supported "Secreted to blood" 1716566667 510000000 "HPA052006: AB_2681691" "unprognostic (5.03e-2)" "unprognostic (4.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (6.48e-2)" "unprognostic (1.39e-1)" "prognostic favourable (3.46e-4)" "unprognostic (4.10e-1)" "unprognostic (2.21e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (2.87e-1)" "unprognostic (9.83e-2)" "unprognostic (5.63e-2)" "unprognostic (1.41e-1)" "unprognostic (9.99e-2)" "unprognostic (2.51e-4)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.1 0.0 9.3 45.0 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.0 2.7 0.0 1.5 0.2 0.9 1.4 0.7 1.0 0.0 0.0 0.6 1.5 0.0 0.0 0.0 3.0 1.8 0.8 0.0 0.0 4.8 0.0 0.0 0.0 0.8 2.4 1.0 2.8 7.6 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 1.0 0.6 0.8 1.8 0.4 1.3 0.2 0.3 0.0 1.1 2.9 0.2 0.0 0.3 1.3 0.0 1.0 0.7 0.8 0.1 0.8 0.3 1.6 0.9 0.8 1.6 0.9 0.7 0.0 0.0 0.0 0.3 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.1 1.5 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PRPF19 "hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4" ENSG00000110107 "Pre-mRNA processing factor 19" Q9UMS4 11 60890730-60906588 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012448, HPA038051, HPA059070" Supported Enhanced "Nuclear speckles" "Nuclear speckles" "CAB012448: AB_2170868, HPA038051: AB_2675807, HPA059070: AB_2683896" "unprognostic (5.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-2)" "prognostic unfavourable (4.11e-8)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (9.37e-3)" "unprognostic (9.53e-2)" "unprognostic (1.54e-1)" "unprognostic (6.70e-2)" "unprognostic (9.62e-2)" "unprognostic (7.12e-2)" "unprognostic (9.04e-2)" "unprognostic (3.41e-3)" 20.5 32.2 33.6 27.0 37.9 32.0 28.9 49.6 61.8 30.4 30.6 21.3 24.5 24.2 27.1 21.4 36.7 34.9 20.1 18.0 32.8 46.3 21.5 39.4 18.0 33.1 35.0 50.0 41.3 31.3 45.7 37.6 24.9 46.2 37.7 31.5 21.5 28.8 30.9 31.9 39.0 24.6 28.8 23.7 28.3 23.7 15.2 24.4 46.3 25.3 24.4 41.7 24.8 24.8 3.1 5.3 4.4 11.8 2.4 3.3 1.2 43.8 34.3 38.6 27.5 22.6 19.9 35.0 23.9 32.5 48.1 36.2 37.7 33.2 63.6 32.2 22.9 40.3 54.2 43.1 37.4 43.3 34.6 52.9 27.2 40.4 32.8 69.9 37.8 21.1 32.8 36.9 41.6 37.3 52.5 36.8 23.5 61.8 70.5 52.6 68.2 46.3 62.7 39.5 49.8 24.3 28.8 32.9 39.6 29.6 49.3 39.8 51.5 38.7 23.3 21.3 34.3 37.1 38.6 32.9 46.0 64.0 26.5 48.0 32.0 4.4 11.8 2.6 3.2 5.4 2.6 1.3 2.6 2.3 4.8 3.1 3.3 3.0 0.7 2.4 2.9 5.3 2.2 1.2 33.6 37.9 49.6 61.8 32.8 46.3 35.0 50.0 46.2 24.4 PRPF4B "KIAA0536, PR4H, Prp4" ENSG00000112739 "Pre-mRNA processing factor 4B" Q13523 6 4021267-4064983 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020638 Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA020638: AB_1855774" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (4.95e-2)" "unprognostic (2.20e-1)" "unprognostic (3.59e-3)" "unprognostic (1.21e-2)" "prognostic unfavourable (2.27e-4)" "unprognostic (8.68e-3)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.50e-3)" "unprognostic (8.90e-2)" "unprognostic (2.34e-1)" "unprognostic (7.63e-3)" "prognostic favourable (6.82e-5)" 23.2 21.6 19.6 24.0 20.5 8.5 21.4 35.6 26.8 18.3 19.3 6.0 14.7 12.0 22.2 14.2 23.6 14.7 13.6 16.3 16.5 11.7 15.0 14.5 13.0 15.4 14.5 14.1 19.1 14.4 20.9 30.9 17.1 21.0 14.9 15.7 5.3 22.7 20.4 45.7 16.3 16.4 14.9 23.7 19.0 13.6 11.6 20.2 21.8 21.1 11.3 17.4 21.4 22.2 9.7 13.6 7.5 11.9 11.8 9.1 3.9 14.4 12.6 19.8 13.6 11.3 10.5 9.6 14.1 15.5 15.4 15.5 12.0 7.3 23.8 17.8 15.8 13.0 25.0 12.2 22.1 11.1 18.3 26.7 14.4 10.7 8.7 29.4 14.6 9.6 8.1 10.9 6.8 15.3 36.5 8.8 15.0 8.5 21.6 9.9 11.9 11.7 24.5 19.2 23.0 9.8 16.4 15.4 10.1 16.3 10.2 12.4 15.9 14.8 16.3 15.1 8.7 9.9 13.6 10.0 15.6 27.7 8.3 13.5 18.4 7.5 11.9 3.6 7.6 9.9 9.1 9.7 8.6 9.0 10.2 9.3 8.0 8.0 6.1 11.8 8.7 13.6 6.3 3.9 19.6 20.5 35.6 26.8 16.5 11.7 14.5 14.1 21.0 20.2 PRPS1 "CMTX5, DFN2, DFNX1" ENSG00000147224 "Phosphoribosyl pyrophosphate synthetase 1" P60891 X 107628424-107651026 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease mutation, Gout, Mental retardation, Neurodegeneration, Neuropathy, Non-syndromic deafness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA043760 Uncertain 140000 "HPA043760: " "unprognostic (4.47e-2)" "unprognostic (6.18e-2)" "unprognostic (2.57e-2)" "unprognostic (4.19e-3)" "unprognostic (2.30e-3)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-1)" "unprognostic (9.73e-2)" "unprognostic (1.91e-2)" "unprognostic (4.11e-2)" "unprognostic (2.85e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.25e-2)" 16.8 19.0 18.8 18.7 22.4 33.5 13.0 27.0 30.3 13.5 12.1 20.5 7.0 7.3 16.6 10.4 11.8 17.6 9.6 19.9 19.0 26.5 18.5 45.1 14.9 25.4 21.8 17.5 21.4 17.8 20.0 18.2 10.0 26.9 14.9 12.4 15.0 11.2 12.4 31.2 8.4 10.8 20.0 19.3 19.4 10.8 11.3 13.6 32.3 29.9 11.3 28.6 16.9 10.7 18.2 8.5 12.6 8.7 14.4 22.1 11.6 20.2 30.2 13.4 15.5 7.5 5.9 4.6 59.7 12.4 34.0 28.8 13.0 8.7 33.5 25.9 21.7 8.3 39.9 12.3 34.9 16.6 24.8 17.8 30.0 16.9 6.9 33.0 13.3 6.7 7.2 20.6 13.5 11.6 28.4 40.6 15.7 10.9 22.3 17.8 48.5 26.1 26.0 21.5 26.9 13.3 11.7 22.1 11.9 29.6 17.9 12.0 8.2 13.8 6.9 22.1 10.4 24.2 23.6 13.9 22.7 36.5 11.4 35.8 13.8 4.8 5.2 12.6 15.7 8.2 17.6 17.0 19.7 19.3 6.2 18.2 22.1 18.7 3.1 14.4 8.7 8.5 20.1 11.6 18.8 22.4 27.0 30.3 19.0 26.5 21.8 17.5 26.9 13.6 PRPS2 ENSG00000101911 "Phosphoribosyl pyrophosphate synthetase 2" P11908 X 12791355-12824222 "Enzymes, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 138.1;testis: 109.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067599, CAB070417" Enhanced Uncertain Vesicles Vesicles "CAB070417: AB_11152035, HPA067599: " "unprognostic (7.50e-2)" "prognostic favourable (1.90e-4)" "unprognostic (2.09e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (4.75e-2)" "unprognostic (6.98e-2)" "unprognostic (2.64e-3)" "unprognostic (4.44e-3)" "unprognostic (1.81e-1)" "unprognostic (7.83e-2)" "unprognostic (2.20e-1)" "unprognostic (1.50e-1)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" 5.4 20.8 4.0 10.2 8.7 6.1 6.1 3.7 11.5 18.7 13.3 5.7 44.4 4.1 17.0 21.7 9.6 9.6 13.2 3.3 4.0 3.5 10.8 9.0 5.4 10.7 2.7 7.7 75.3 19.9 20.1 2.4 3.2 2.9 14.9 10.2 4.4 11.1 138.1 1.5 10.3 6.3 12.2 3.9 7.6 14.3 109.7 3.1 26.2 7.8 5.5 10.9 15.1 10.2 21.9 17.7 10.5 12.5 15.0 22.7 16.7 31.0 20.6 7.2 13.0 8.9 10.5 4.0 15.5 8.5 17.2 16.7 14.6 25.0 9.1 7.0 7.4 23.6 13.8 16.9 20.3 24.5 29.8 11.2 17.0 13.5 8.2 22.1 11.5 10.1 11.4 12.7 17.0 7.0 8.3 12.7 14.5 21.4 33.7 10.2 15.3 27.8 18.0 30.8 23.3 10.3 25.8 13.9 9.4 18.7 0.7 11.7 18.6 10.0 6.5 13.5 9.8 49.5 16.5 30.0 11.0 21.7 14.2 11.2 21.2 10.5 12.5 5.6 11.7 12.4 13.6 18.0 17.0 11.1 17.7 21.9 22.7 15.3 5.5 15.0 7.7 12.6 14.0 16.7 4.0 8.7 3.7 11.5 4.0 3.5 2.7 7.7 2.9 3.1 PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753076 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1708 "pancreas: 3057.4" "Cell line enhanced" "Detected in some" "EFO-21: 3.5;HDLM-2: 1.7;RPMI-8226: 6.9;U-2 OS: 4.1;U-251 MG: 1.5;U-266/84: 2.5" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 1.7" "Low lineage specificity" "Detected in many" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" 26000000000 Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: , HPA063471: " "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavourable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favourable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favourable (4.91e-4)" "unprognostic (3.12e-1)" 0.4 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.6 3057.4 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.4 0.2 0.1 0.0 0.4 0.1 0.1 0.1 0.5 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 0.0 1.7 0.0 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 1.5 0.0 2.5 0.6 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 PRSS12 "BSSP-3, MRT1" ENSG00000164099 "Serine protease 12" P56730 4 118280038-118353003 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 27.5;testis: 31.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 20.4;SH-SY5Y: 64.8;THP-1: 29.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 11.6;basal ganglia: 8.7;cerebral cortex: 26.5;hippocampal formation: 15.3;olfactory region: 11.0" "Low region specificity" "Detected in all" HPA035054 Uncertain Approved "Nucleoplasm,Actin filaments" "Secreted - unknown location" "Actin filaments" Nucleoplasm "HPA035054: AB_10603990" "unprognostic (4.30e-2)" "unprognostic (1.04e-2)" "unprognostic (2.55e-1)" "unprognostic (4.41e-2)" "prognostic favourable (2.66e-4)" "prognostic favourable (1.03e-4)" "unprognostic (4.21e-1)" "unprognostic (3.48e-2)" "unprognostic (7.83e-2)" "unprognostic (6.38e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.29e-1)" "unprognostic (1.85e-1)" "unprognostic (9.55e-2)" "unprognostic (1.09e-1)" 0.9 0.5 2.1 4.1 1.4 0.0 1.9 0.5 2.8 16.5 6.0 2.0 1.3 2.2 3.0 2.7 3.6 9.8 27.5 0.3 2.2 0.9 1.1 0.8 8.0 0.0 0.7 2.4 1.9 9.8 0.0 0.9 20.4 4.1 2.0 5.8 20.0 3.1 3.2 0.3 5.9 8.6 1.0 0.5 0.3 8.1 31.3 0.2 0.3 0.6 7.7 7.7 3.1 16.2 0.3 0.4 0.0 0.1 0.0 0.7 0.0 1.4 0.0 0.5 0.0 0.0 4.1 0.0 13.5 12.2 2.9 4.8 0.0 5.5 0.0 0.0 20.4 0.2 9.1 2.7 3.8 0.0 2.1 0.0 1.1 0.0 0.4 0.0 0.0 1.2 5.2 1.0 3.0 0.0 0.0 0.0 2.3 0.0 0.1 2.7 0.6 0.8 0.0 11.5 0.0 0.0 2.0 1.5 64.8 0.0 0.0 0.8 0.0 29.0 0.0 5.8 0.8 3.6 2.6 0.3 0.0 0.0 0.3 0.9 3.3 0.0 0.1 0.0 0.0 0.1 0.7 0.3 0.0 0.0 0.4 0.3 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 2.1 1.4 0.5 2.8 2.2 0.9 0.7 2.4 4.1 0.2 PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 708 "pancreas: 6267.9" "Cell line enriched" "Detected in some" 5 "RPMI-8226: 37.2" "Cancer enriched" "Detected in many" 72 "pancreatic cancer: 3463.4" "Group enriched" "Detected in some" 6 "basophil: 5.6;T-reg: 5.1" "Group enriched" "Detected in many" 6 "granulocytes: 5.6;T-cells: 5.1" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" 27000000000 Vesicles "Endoplasmic reticulum" "HPA062452: , HPA063471: " "prognostic favourable (2.32e-4)" "unprognostic (3.80e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-3)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (3.50e-1)" "unprognostic (5.36e-3)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 6267.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 5.6 0.0 0.7 5.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.4 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.5 2.1 0.0 1.6 0.2 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.1 0.3 PRSS21 "ESP-1, TEST1" ENSG00000007038 "Serine protease 21" Q9Y6M0 16 2817180-2826304 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 21.0;salivary gland: 20.9;testis: 37.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 10.2;HEL: 11.3;HeLa: 29.2;K-562: 13.4;U-698: 41.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 23.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 10.5;eosinophil: 21.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 21.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 27 "basal ganglia: 6.7" HPA008477 Enhanced Approved Cytosol "Intracellular and membrane" Cytosol "HPA008477: AB_1079697" "unprognostic (4.35e-2)" "unprognostic (3.46e-2)" "unprognostic (7.06e-2)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (7.02e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (2.33e-1)" "unprognostic (5.21e-2)" "unprognostic (8.83e-3)" "unprognostic (1.52e-3)" "unprognostic (2.97e-2)" "unprognostic (1.14e-2)" "unprognostic (5.07e-2)" "unprognostic (7.79e-2)" "unprognostic (2.99e-1)" 0.8 0.0 0.2 0.2 0.2 5.5 1.0 0.4 0.4 1.4 0.4 0.2 1.4 0.2 0.3 0.2 0.8 2.2 2.1 0.2 0.2 0.0 0.2 0.2 2.1 3.3 0.2 0.2 0.3 0.9 1.7 0.2 0.3 0.4 1.8 0.2 0.2 20.9 0.2 0.5 0.4 0.4 0.2 0.2 0.9 0.4 37.5 0.2 0.9 0.2 1.2 1.1 0.3 0.6 0.8 1.4 21.0 2.3 1.0 3.3 1.3 4.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 11.3 29.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 10.5 2.3 21.0 2.2 1.6 3.3 0.8 1.1 1.8 0.6 0.6 1.5 2.2 0.2 1.0 0.3 1.4 0.5 1.3 0.2 0.2 0.4 0.4 0.2 0.0 0.2 0.2 0.4 0.2 PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852727-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.4;lymphoid tissue: 40.1;tongue: 36.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.6;MCF7: 12.4;RT4: 5.8;SK-BR-3: 13.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 16 "cerebellum: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" Nucleoplasm "HPA049161: " "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" 0.4 0.7 0.0 0.4 0.0 0.6 1.3 1.5 0.4 9.9 1.0 0.0 8.6 1.5 3.0 0.6 40.4 3.0 6.8 0.4 0.0 0.0 2.4 0.7 3.0 0.4 0.0 0.0 0.4 7.5 0.4 1.1 4.3 0.0 5.1 0.6 0.0 13.4 10.6 2.3 1.3 0.4 0.7 0.0 0.4 3.5 0.4 0.0 0.0 1.5 36.5 40.1 5.2 9.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 13.1 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS23 "SIG13, SPUVE" ENSG00000150687 "Serine protease 23" O95084 11 86791059-86952910 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 59.0;HUVEC TERT2: 73.6;TIME: 137.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 36.4" "Group enriched" "Detected in many" 30 "NK-cells: 10.2;T-cells: 36.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA030591 Uncertain "Secreted to blood" 290000 "HPA030591: AB_10602067" "unprognostic (2.68e-2)" "unprognostic (1.20e-2)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (2.40e-3)" "prognostic unfavourable (2.12e-4)" "unprognostic (1.89e-2)" "unprognostic (4.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.09e-1)" "prognostic unfavourable (5.56e-4)" "unprognostic (5.35e-2)" "prognostic unfavourable (3.06e-4)" "unprognostic (5.13e-3)" "unprognostic (9.44e-2)" "unprognostic (1.99e-3)" "unprognostic (8.01e-2)" 19.5 8.7 2.3 10.8 4.1 0.4 40.7 1.2 2.6 89.0 33.8 2.1 37.2 5.1 44.9 27.4 14.5 9.6 45.6 17.2 5.0 3.0 17.5 10.4 36.2 15.9 3.7 4.4 16.2 14.3 9.6 6.3 30.2 12.5 36.7 14.4 15.2 17.6 37.3 19.1 7.2 12.4 100.2 4.9 7.3 22.0 19.5 1.4 3.8 15.3 10.5 5.8 68.6 31.1 0.0 0.0 0.5 0.7 10.2 36.4 10.9 7.3 18.5 19.9 0.1 8.9 21.9 0.0 32.5 29.9 36.3 29.1 42.9 59.0 0.0 25.9 49.8 15.3 0.3 24.8 8.8 0.0 1.5 2.5 9.5 0.1 4.5 0.0 0.1 17.4 3.3 17.7 20.2 73.6 0.1 0.0 27.3 10.1 0.0 0.0 1.2 2.0 0.0 0.0 0.0 13.6 9.9 0.1 0.1 7.2 0.5 2.2 0.7 0.0 137.4 21.7 0.2 43.3 18.4 0.1 0.1 0.0 15.5 0.0 21.4 0.0 0.0 0.0 36.4 0.0 0.0 0.0 6.6 20.5 0.0 0.0 1.8 18.5 0.5 10.2 0.7 0.0 0.0 10.9 2.3 4.1 1.2 2.6 5.0 3.0 3.7 4.4 12.5 1.4 PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712418-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 94.1;lymphoid tissue: 97.2;tongue: 64.5" "Cell line enhanced" "Detected in some" "BEWO: 5.4;SK-BR-3: 21.8;T-47d: 12.8;U-266/70: 4.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 1.4;myeloid DC: 1.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;T-cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" 0.2 0.3 0.1 0.2 0.5 0.2 0.4 0.7 0.4 15.3 0.2 0.1 0.1 0.1 1.2 0.1 94.1 0.3 0.2 0.2 0.1 0.4 0.2 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.5 0.1 0.2 0.1 0.2 0.1 0.1 10.0 0.3 0.2 1.2 0.1 0.2 0.1 0.2 0.1 0.5 0.1 0.3 0.2 64.5 97.2 0.5 24.0 0.1 1.7 0.2 0.0 0.2 1.4 1.2 0.0 0.2 0.5 1.8 0.3 0.6 5.4 0.0 0.2 0.2 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.1 0.1 0.0 0.9 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 1.6 0.0 0.9 1.3 0.0 0.8 0.2 0.1 0.1 0.3 0.6 2.6 0.0 21.8 0.5 12.8 1.5 0.0 0.3 0.0 0.0 0.0 4.5 3.1 0.4 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.4 0.0 1.7 0.0 0.3 0.7 0.2 0.2 0.0 0.0 0.0 1.2 0.1 0.5 0.7 0.1 0.1 0.4 0.1 0.1 0.1 0.1 PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750466-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "pancreas: 984.9" "Cell line enriched" "Detected in some" 8 "PC-3: 121.9" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 82 "basophil: 39.0" "Lineage enriched" "Detected in single" 82 "granulocytes: 39.0" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" 490000000 Vesicles "Endoplasmic reticulum" "HPA062452: , HPA063471: " "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavourable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" 0.3 0.3 1.6 1.7 1.5 0.2 0.2 2.8 4.2 0.9 8.2 0.0 0.0 2.8 0.2 0.2 2.9 0.2 4.8 0.4 1.2 0.7 0.3 0.4 0.2 0.2 0.3 1.6 0.7 984.9 0.2 0.1 0.2 2.3 0.2 2.3 0.0 0.6 0.2 0.2 2.0 23.9 0.3 0.2 0.2 0.8 0.3 0.0 0.0 0.2 6.6 3.5 0.2 1.3 0.0 0.1 39.0 0.4 0.1 0.3 0.1 1.7 2.0 0.1 0.0 0.0 0.9 0.0 4.8 1.1 0.5 0.2 4.7 0.4 0.0 0.0 2.1 2.1 0.0 4.4 1.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.5 15.9 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 121.9 0.0 0.0 0.0 0.0 0.2 0.0 12.3 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 39.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 1.6 1.5 2.8 4.2 1.2 0.7 0.3 1.6 2.3 0.0 PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512538-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 17.1;ovary: 16.3" "Group enriched" "Detected in some" 4 "CACO-2: 42.1;RPTEC TERT1: 12.4" "Cancer enhanced" "Detected in some" "testis cancer: 4.7" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 9 "MAIT T-cell: 17.1" "Lineage enriched" "Detected in single" 172 "T-cells: 17.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 4.2;cerebellum: 7.0;cerebral cortex: 7.5;hippocampal formation: 6.8;olfactory region: 5.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" 2.0 3.8 7.7 1.3 11.3 0.0 0.6 0.2 9.3 4.8 0.4 2.5 0.3 0.5 2.2 2.1 0.6 2.2 6.2 5.6 4.8 1.1 4.9 0.7 2.0 3.0 1.1 5.4 16.3 0.6 0.9 1.5 5.2 2.7 2.7 0.6 11.1 0.4 0.7 0.4 0.5 0.4 2.2 1.4 1.1 0.6 4.6 1.3 0.0 0.7 0.4 0.2 2.0 0.9 0.0 0.0 0.0 0.0 0.0 17.1 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.1 5.1 0.5 1.0 42.1 0.0 0.0 0.0 0.2 0.0 6.3 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 4.1 0.0 0.0 0.0 12.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 17.1 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.7 11.3 0.2 7.1 4.8 1.1 1.1 5.4 2.7 1.3 PRSS36 FLJ90661 ENSG00000178226 "Serine protease 36" Q5K4E3 16 31138925-31150094 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 2.2;HeLa: 6.3;HMC-1: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "eosinophil: 4.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036079 Uncertain "Secreted - unknown location" "HPA036079: AB_10602290" "unprognostic (3.74e-2)" "prognostic favourable (2.97e-7)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (4.26e-3)" "unprognostic (1.31e-5)" "unprognostic (4.18e-2)" "unprognostic (5.05e-2)" "unprognostic (2.65e-2)" "unprognostic (8.03e-2)" "unprognostic (2.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (9.86e-2)" "unprognostic (1.23e-1)" "unprognostic (3.13e-1)" 3.0 2.0 0.4 1.0 1.2 1.1 6.2 0.4 1.8 1.6 1.8 0.4 0.4 3.2 0.4 1.8 1.2 0.5 0.4 2.1 0.4 0.5 0.5 0.7 2.3 0.4 0.4 0.4 1.7 0.4 0.4 6.5 2.5 0.4 1.0 0.9 0.4 3.5 0.4 1.3 3.4 2.1 1.2 0.4 0.4 1.0 0.7 0.4 0.4 0.6 0.4 1.0 2.0 0.4 0.0 2.1 4.3 0.8 0.2 0.4 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.2 0.3 0.3 0.2 0.1 0.4 1.4 0.0 0.8 0.3 1.3 0.1 0.2 0.0 0.2 0.6 2.2 6.3 1.1 0.1 0.3 2.8 0.2 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.5 0.0 0.3 0.4 0.1 0.5 0.1 0.0 0.0 0.2 0.3 0.0 0.6 0.7 0.0 0.1 1.2 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 4.3 0.2 0.1 0.1 0.0 0.0 0.0 2.1 0.0 0.1 0.4 2.6 0.2 0.0 0.6 0.1 0.1 0.4 1.2 0.4 1.8 0.4 0.5 0.4 0.4 0.4 0.4 PRSS37 ENSG00000165076 "Serine protease 37" A4D1T9 7 141836286-141841487 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 127 "testis: 39.1" "Cell line enhanced" "Detected in some" "HL-60: 2.3;U-937: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA020541 Enhanced "Secreted in male reproductive system" "HPA020541: AB_1853004" "unprognostic (4.70e-2)" "unprognostic (5.56e-2)" "unprognostic (2.69e-1)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (1.30e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-2)" "unprognostic (8.30e-7)" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (2.72e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 39.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.2 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS38 MPN2 ENSG00000185888 "Serine protease 38" A1L453 1 227815693-227846470 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "blood: 2.2;testis: 8.4" "Cell line enriched" "Detected in single" 20 "U-266/84: 5.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "gdT-cell: 1.4;NK-cell: 2.2" "Group enriched" "Detected in many" 18 "NK-cells: 2.2;T-cells: 1.4" "Not detected" "Not detected" "HPA028003, HPA055809" Enhanced "Secreted in male reproductive system" "HPA028003: AB_1853572, HPA055809: AB_2682931" "unprognostic (9.54e-3)" "unprognostic (3.61e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 PRSS42 TESSP2 ENSG00000178055 "Serine protease 42" Q7Z5A4 3 46829542-46834095 "Enzymes, Predicted secreted proteins" "Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "heart muscle: 12.9;skeletal muscle: 19.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.3;Daudi: 3.9;Karpas-707: 2.4;NTERA-2: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046925 Uncertain "Secreted - unknown location" "HPA046925: AB_10961401" "unprognostic (6.53e-2)" "unprognostic (2.72e-2)" "unprognostic (3.57e-3)" "unprognostic (9.14e-2)" "unprognostic (3.26e-1)" "unprognostic (2.37e-2)" "unprognostic (1.85e-1)" "unprognostic (6.54e-2)" "unprognostic (4.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (1.09e-2)" "unprognostic (1.38e-1)" "unprognostic (1.62e-1)" "unprognostic (7.98e-2)" 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.2 0.0 0.2 3.4 0.0 0.2 0.0 12.9 0.0 0.0 1.3 0.5 0.2 0.0 0.0 0.2 0.2 1.6 0.0 0.1 0.4 0.0 0.3 0.2 19.2 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.8 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.8 0.2 1.6 0.0 0.0 0.0 0.7 0.2 2.3 3.9 0.4 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.0 0.4 3.6 0.0 1.2 0.0 0.0 0.1 0.0 0.6 0.5 0.5 0.0 0.3 0.0 0.5 0.0 1.0 0.7 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS45 TESSP5 ENSG00000188086 "Serine protease 45" Q7RTY3 3 46742092-46744755 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 7.6;skeletal muscle: 6.7" "Cell line enhanced" "Detected in some" "Daudi: 1.2;HBF TERT88: 1.0;HHSteC: 2.6" "Low cancer specificity" "Detected in single" "Cell type enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" HPA060284 Uncertain "HPA060284: " "unprognostic (4.55e-3)" "unprognostic (3.49e-2)" "unprognostic (1.07e-2)" "unprognostic (2.50e-1)" "unprognostic (6.07e-2)" "unprognostic (1.28e-2)" "unprognostic (1.06e-1)" "unprognostic (6.20e-2)" "unprognostic (1.54e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-4)" "unprognostic (2.33e-2)" "unprognostic (6.60e-3)" "unprognostic (1.27e-2)" "unprognostic (1.57e-2)" "unprognostic (2.15e-1)" "unprognostic (5.97e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.5 0.2 0.1 0.2 7.6 0.1 0.8 0.0 0.2 0.0 0.0 0.9 0.7 0.2 0.1 0.0 0.3 1.3 2.0 0.5 0.1 0.5 0.0 0.5 0.3 6.7 0.3 0.0 0.0 0.0 0.0 0.2 1.6 3.2 0.0 0.4 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS48 ESSPL ENSG00000189099 "Serine protease 48" Q7RTY5 4 151277171-151291453 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 1.0;skin 1: 1.9;testis: 4.1" "Cell line enhanced" "Detected in some" "HHSteC: 1.4;LHCN-M2: 1.3;PC-3: 1.5;RT4: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053801 Uncertain "Secreted in male reproductive system" "HPA053801: " "unprognostic (9.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (3.76e-2)" "unprognostic (4.10e-2)" 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.6 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 PRSS50 "CT20, TSP50" ENSG00000206549 "Serine protease 50" Q9UI38 3 46712115-46812574 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.3" "Cell line enhanced" "Detected in some" "BEWO: 1.0;NTERA-2: 2.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA040768 Supported "HPA040768: " "unprognostic (1.19e-2)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.32e-1)" "unprognostic (7.45e-2)" "unprognostic (9.24e-2)" "unprognostic (1.37e-1)" "unprognostic (6.77e-2)" "unprognostic (2.23e-1)" "unprognostic (8.91e-4)" "unprognostic (1.08e-1)" "unprognostic (1.46e-3)" "unprognostic (2.68e-2)" "unprognostic (1.79e-2)" "unprognostic (9.36e-2)" "unprognostic (3.66e-3)" 0.1 0.7 0.0 0.0 0.0 0.0 0.6 0.4 0.3 1.3 0.2 0.1 0.7 6.2 0.1 0.5 0.0 0.9 0.0 0.6 1.8 0.7 0.2 0.0 0.0 0.7 1.7 4.7 8.2 0.0 1.6 0.0 1.7 1.7 7.7 0.0 0.0 0.2 0.0 0.0 0.2 22.3 7.9 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS50 "CT20, TSP50" ENSG00000283706 "Serine protease 50" Q9UI38 3 46712115-46717907 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 33.4" "Cell line enhanced" "Detected in some" "EFO-21: 2.0;HMC-1: 5.3;NTERA-2: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA040768 Supported "Intracellular and membrane" "HPA040768: " 0.1 0.8 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 2.9 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.3 0.9 1.7 1.1 0.1 0.1 0.2 0.0 0.1 1.6 1.8 0.1 0.0 0.1 0.1 0.1 0.1 0.0 33.4 0.1 0.4 1.6 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.5 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PRSS53 POL3S ENSG00000151006 "Serine protease 53" Q2L4Q9 16 31083425-31089628 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "liver: 10.9" "Cell line enhanced" "Detected in some" "SCLC-21H: 9.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034955, HPA034956" Uncertain "Secreted - unknown location" "HPA034955: , HPA034956: AB_10696365" "unprognostic (3.13e-1)" "unprognostic (4.15e-1)" "unprognostic (3.88e-3)" "unprognostic (1.62e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.63e-2)" "unprognostic (1.04e-2)" "unprognostic (2.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.63e-4)" "unprognostic (2.53e-12)" "unprognostic (1.02e-1)" "unprognostic (2.01e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" 0.3 0.0 0.0 0.5 0.3 0.0 0.1 2.9 0.4 0.2 0.3 1.4 1.0 0.0 0.1 0.3 0.6 0.2 0.1 0.3 0.6 10.9 0.5 0.9 0.1 0.3 2.2 0.0 0.8 0.2 1.2 0.0 0.0 0.8 0.0 3.9 0.5 0.4 0.2 1.0 1.3 0.0 0.3 0.0 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.4 0.8 0.3 0.0 0.3 0.0 0.0 0.0 1.0 0.5 1.1 1.0 0.0 0.2 0.0 0.3 0.7 0.0 1.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.5 0.0 0.0 0.0 0.1 0.3 0.1 1.3 0.3 1.6 0.8 1.9 1.6 0.0 0.0 0.0 0.0 9.8 0.8 0.9 0.0 1.0 0.7 0.1 0.7 1.0 0.7 2.5 0.2 1.4 0.1 0.3 2.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 PRSS54 "CT67, FLJ25339, KLKBL4" ENSG00000103023 "Serine protease 54" Q6PEW0 16 58279997-58295047 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 95 "testis: 35.1" "Cell line enhanced" "Detected in single" "BEWO: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041549 Enhanced "Secreted in male reproductive system" "HPA041549: AB_10795640" "unprognostic (1.13e-1)" "unprognostic (3.24e-2)" "unprognostic (3.09e-2)" "unprognostic (3.08e-1)" "unprognostic (4.88e-2)" "unprognostic (1.23e-1)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PRSS8 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135762 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 123.2;salivary gland: 143.7" "Cell line enhanced" "Detected in some" "BEWO: 57.3;CACO-2: 37.6;CAPAN-2: 25.8;hTCEpi: 37.0;SK-BR-3: 43.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 4 "pons and medulla: 3.4" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA030436 Uncertain "Secreted - unknown location" 3500000 "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favourable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" 0.3 0.2 0.3 11.5 0.3 0.0 7.6 0.7 0.4 8.0 72.6 0.6 12.8 31.6 3.4 46.7 37.2 2.8 45.3 0.3 0.4 0.3 48.0 20.3 30.0 0.3 0.3 0.3 1.3 46.3 2.7 2.6 93.1 3.4 11.4 14.7 1.1 143.7 7.4 0.3 29.7 123.2 0.5 0.3 0.3 37.0 1.8 0.3 11.3 33.4 18.4 26.7 2.6 13.4 0.2 0.0 1.0 0.3 0.0 0.2 0.0 14.2 0.0 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 37.6 25.8 0.0 0.3 0.0 17.0 0.0 16.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 37.0 0.0 0.5 0.0 0.4 0.0 0.0 15.3 0.1 0.3 4.7 0.0 0.1 0.0 0.2 1.7 3.0 0.2 0.1 0.0 43.5 0.0 9.9 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.7 0.4 0.4 0.3 0.3 0.3 3.4 0.3 PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840960-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "bone marrow: 167.3" "Cell line enriched" "Detected in some" 5 "THP-1: 148.0" "Cancer enhanced" "Detected in single" "stomach cancer: 1.0" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced "Secreted to blood" 120000 "CAB017558: AB_2172317, HPA005938: AB_1855764" "unprognostic (2.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.83e-3)" "unprognostic (4.20e-1)" "unprognostic (3.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.98e-3)" "unprognostic (3.67e-2)" "unprognostic (8.62e-6)" "unprognostic (5.31e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" 0.3 0.2 0.9 0.2 1.0 167.3 0.2 0.0 2.3 0.2 0.2 0.7 0.0 0.2 0.2 0.2 0.2 0.2 0.2 31.0 0.3 0.6 0.2 1.7 8.1 3.5 0.1 0.1 0.4 0.2 0.2 0.8 4.2 0.8 0.2 0.2 0.3 0.3 0.2 0.5 0.3 0.2 0.2 0.0 25.5 0.2 0.2 0.1 35.0 0.9 0.0 0.2 0.2 0.0 0.0 0.0 1.9 0.1 0.0 0.2 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 6.8 0.9 1.0 0.0 2.3 0.3 0.6 0.1 0.1 0.8 0.1 PRUNE1 "DRES-17, H-PRUNE, HTCD37, PRUNE" ENSG00000143363 "Prune exopolyphosphatase 1" Q86TP1 1 151008420-151035713 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 61.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028411 Uncertain Supported Cytosol 210000 Cytosol "HPA028411: AB_10603229" "unprognostic (6.24e-2)" "unprognostic (2.24e-1)" "unprognostic (4.17e-2)" "prognostic unfavourable (3.86e-4)" "unprognostic (6.91e-2)" "unprognostic (2.02e-1)" "unprognostic (2.12e-3)" "unprognostic (7.05e-2)" "unprognostic (4.08e-2)" "unprognostic (5.92e-2)" "unprognostic (1.73e-1)" "unprognostic (2.65e-1)" "prognostic unfavourable (3.48e-4)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-1)" 9.3 9.7 9.3 8.8 11.6 3.7 16.0 15.7 16.4 15.0 12.5 10.9 16.2 11.7 17.9 15.7 11.5 15.6 12.8 31.3 10.5 10.3 18.0 12.8 10.1 11.8 11.9 9.2 17.1 16.2 16.5 16.2 7.2 8.8 12.2 14.0 12.7 13.3 18.2 24.4 10.5 11.8 14.7 7.9 11.0 10.5 16.3 8.6 15.0 41.6 8.5 12.9 13.8 13.6 12.1 9.5 14.7 8.9 14.3 19.0 18.3 3.8 4.1 7.4 7.1 9.2 2.5 4.1 1.8 4.0 6.9 6.0 5.1 4.6 7.9 8.0 2.4 5.6 7.2 4.8 5.5 8.6 8.2 9.3 4.3 7.2 5.1 6.1 4.7 3.1 9.2 3.6 3.6 3.2 7.3 6.7 3.2 9.3 9.3 5.0 6.9 5.4 8.5 4.7 7.6 4.9 5.3 10.7 8.7 6.2 8.6 5.7 11.9 9.3 2.2 2.4 2.9 2.7 2.9 16.4 13.8 61.0 2.4 4.7 6.1 12.5 6.4 13.4 14.0 6.0 16.9 12.1 15.5 15.7 9.5 11.6 19.0 15.0 14.7 14.3 8.9 5.1 14.5 18.3 9.3 11.6 15.7 16.4 10.5 10.3 11.9 9.2 8.8 8.6 PSAT1 PSA ENSG00000135069 "Phosphoserine aminotransferase 1" Q9Y617 9 78297143-78330093 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" "Aminotransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 56.0;liver: 112.2" "Cell line enhanced" "Detected in many" "hTCEpi: 148.4;SK-MEL-30: 90.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 13.3" "Lineage enriched" "Detected in many" 4 "T-cells: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014882, CAB040567, HPA042924" Enhanced Enhanced Cytosol 1700000 Cytosol "CAB014882: , CAB040567: , HPA042924: " "unprognostic (8.26e-3)" "unprognostic (4.69e-2)" "unprognostic (1.46e-1)" "prognostic unfavourable (5.62e-5)" "unprognostic (4.05e-3)" "unprognostic (1.41e-1)" "unprognostic (2.21e-3)" "unprognostic (1.86e-1)" "unprognostic (9.85e-2)" "unprognostic (2.25e-2)" "unprognostic (4.53e-2)" "unprognostic (1.07e-1)" "prognostic unfavourable (6.00e-7)" "unprognostic (3.87e-3)" "unprognostic (1.21e-1)" "unprognostic (8.07e-3)" "unprognostic (1.71e-1)" 3.1 25.0 44.6 3.8 33.4 1.7 3.0 8.5 50.5 2.4 3.3 44.8 0.9 3.2 2.7 28.4 9.3 16.0 1.6 1.4 33.9 22.3 56.0 112.2 1.6 4.5 42.2 24.6 3.7 54.6 4.8 2.1 2.2 21.9 5.3 3.3 8.1 26.2 2.8 1.1 24.7 2.8 2.3 29.8 2.4 7.0 5.1 35.0 2.2 13.7 4.9 5.9 4.2 2.6 3.0 0.2 0.2 0.1 0.0 13.3 3.1 26.8 18.1 15.2 27.0 4.5 5.3 36.0 22.8 16.3 11.6 21.8 4.6 5.2 17.4 10.1 51.3 26.7 26.0 25.2 17.4 17.0 9.2 5.9 8.3 35.5 41.8 33.2 10.7 16.9 148.4 15.4 41.3 10.6 6.4 45.0 9.6 10.0 11.3 5.3 34.9 19.8 5.6 9.9 20.5 15.8 6.2 6.9 16.1 6.3 11.0 90.8 5.2 41.9 2.4 2.9 9.5 10.8 18.5 30.6 28.2 0.1 34.3 26.3 13.9 0.0 0.0 0.0 4.9 0.0 5.7 3.0 4.8 6.5 0.2 1.0 7.9 7.3 0.2 0.0 0.1 0.0 13.3 3.1 44.6 33.4 8.5 24.9 33.9 22.3 42.2 24.6 21.9 35.0 PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006844, HPA030760, HPA067496" Approved Approved "Nucleoplasm,Golgi apparatus,Cell Junctions" "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: AB_10696211, HPA067496: " "unprognostic (1.67e-1)" "unprognostic (4.79e-2)" "unprognostic (7.39e-2)" "unprognostic (8.68e-3)" "unprognostic (3.84e-1)" "unprognostic (5.48e-3)" "prognostic unfavourable (1.99e-5)" "unprognostic (1.65e-1)" "unprognostic (8.99e-2)" "unprognostic (8.45e-2)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "prognostic favourable (1.52e-8)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (7.12e-3)" "unprognostic (1.85e-1)" 16.3 15.3 21.0 13.4 34.9 19.2 15.7 15.5 24.7 16.5 26.2 66.1 9.5 26.6 14.2 15.4 19.0 12.6 17.1 9.9 28.6 18.2 19.7 16.9 16.9 10.8 42.1 20.7 13.5 15.0 21.8 9.2 22.7 31.8 13.6 25.6 15.0 16.8 13.4 13.0 24.7 27.9 14.6 61.9 14.6 16.3 16.8 39.7 15.4 19.7 8.7 15.9 17.2 13.5 9.0 24.4 38.1 34.0 11.7 10.5 17.1 14.2 21.9 20.5 8.1 28.7 20.5 18.7 21.0 24.1 21.5 27.2 27.2 35.7 9.3 13.9 19.9 38.0 17.2 15.9 23.6 21.2 10.7 10.6 14.9 13.2 26.5 10.7 20.8 21.0 28.9 17.8 22.0 17.2 11.8 19.0 20.1 28.3 8.1 13.9 8.9 16.3 10.3 17.4 11.8 30.0 30.3 11.4 15.2 22.9 21.5 18.7 26.6 23.9 18.2 21.9 18.1 17.9 9.9 12.4 18.2 9.4 18.4 13.0 13.3 29.2 27.1 27.1 7.2 30.8 7.0 7.2 7.0 5.9 24.4 9.0 6.6 6.4 38.1 11.7 34.0 12.8 10.5 17.1 21.0 34.9 15.5 24.7 28.6 18.2 42.1 20.7 31.8 39.7 PSEN2 "AD3L, AD4, PS2, STM2" ENSG00000143801 "Presenilin 2" P49810 1 226870184-226896105 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cardiomyopathy, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013634, HPA038005" Supported Nucleoplasm Nucleoplasm "CAB013634: , HPA038005: " "unprognostic (3.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.94e-1)" "unprognostic (3.86e-2)" "unprognostic (6.54e-2)" "unprognostic (1.64e-3)" "unprognostic (4.72e-2)" "unprognostic (1.31e-1)" "unprognostic (9.98e-2)" "unprognostic (2.73e-2)" "unprognostic (8.25e-3)" "unprognostic (8.53e-3)" "unprognostic (8.45e-2)" "unprognostic (1.17e-1)" "unprognostic (8.36e-2)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" 8.9 13.2 9.5 5.9 7.9 1.2 8.1 16.6 10.7 9.2 9.2 5.9 7.3 9.4 16.4 9.0 9.4 8.7 12.0 9.7 6.5 10.8 7.8 7.7 9.0 11.6 8.1 9.3 13.1 31.6 14.0 15.2 7.6 14.8 12.8 6.9 15.9 9.6 13.4 22.1 6.8 12.2 17.0 4.9 10.6 7.1 21.8 5.3 1.4 6.0 7.2 7.0 9.0 7.2 5.1 7.7 19.4 18.7 12.3 3.4 3.1 8.9 13.4 4.0 12.4 5.5 1.8 6.7 7.6 14.9 9.5 7.3 10.5 11.5 0.1 10.3 9.7 4.6 7.1 7.2 3.9 9.6 12.9 6.1 9.5 6.8 9.2 4.7 10.0 5.3 8.1 11.4 6.2 4.4 10.4 4.1 5.5 7.5 0.1 5.4 12.3 11.1 0.1 14.7 14.4 8.4 7.6 7.0 11.7 6.1 16.9 30.2 14.5 6.0 4.8 6.8 5.7 6.2 9.5 16.4 24.1 0.4 12.0 1.5 8.9 19.4 5.7 12.1 3.2 6.5 3.4 5.1 1.1 2.9 7.7 2.6 0.6 1.7 1.2 12.3 18.7 0.6 1.4 3.1 9.5 7.9 16.6 10.7 6.5 10.8 8.1 9.3 14.8 5.3 PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893272-67929678 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053927 Approved Approved Nucleoplasm Nucleoplasm "HPA053927: AB_2682312" "unprognostic (2.57e-2)" "unprognostic (8.91e-3)" "unprognostic (1.88e-1)" "unprognostic (5.79e-2)" "unprognostic (3.26e-1)" "unprognostic (3.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-2)" "unprognostic (9.85e-3)" "unprognostic (8.32e-2)" "prognostic favourable (4.28e-10)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (4.15e-2)" "unprognostic (3.90e-3)" 14.3 18.3 13.6 14.0 16.6 4.8 15.1 13.3 13.3 11.0 14.7 17.7 24.0 14.0 19.2 14.6 17.7 20.2 19.3 17.8 12.2 8.4 18.8 15.1 13.1 10.4 16.2 12.7 21.2 35.3 33.2 13.0 9.8 16.1 14.3 11.4 16.2 19.0 14.8 19.9 14.0 15.2 16.3 11.3 12.8 19.1 31.7 15.0 12.5 14.9 12.9 8.6 14.8 18.7 4.0 5.2 4.5 5.8 5.2 5.6 3.5 7.3 13.1 14.9 16.5 23.3 11.8 9.7 8.8 13.5 9.4 8.4 9.9 10.6 6.9 13.5 14.9 11.2 8.6 9.1 3.2 2.7 9.6 7.9 9.7 12.5 16.0 7.5 4.8 21.7 15.8 11.1 11.8 13.7 12.0 3.0 9.7 16.4 10.2 4.8 14.3 8.2 15.7 5.7 14.3 11.1 9.2 13.0 15.5 27.4 7.5 9.0 13.8 13.7 12.0 10.6 3.8 8.8 4.4 9.1 4.8 14.9 12.8 5.1 11.6 0.0 4.3 4.5 5.6 5.8 3.8 4.0 3.9 5.3 5.2 3.5 3.4 4.3 2.7 5.2 3.6 3.8 2.3 3.5 13.6 16.6 13.3 13.3 12.2 8.4 16.2 12.7 16.1 15.0 PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86048373-86088621 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "kidney: 1.9;placenta: 1.2;testis: 2.0" "Cell line enriched" "Detected in single" 18 "HEL: 13.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015095, HPA056839" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: AB_1855815, HPA056839: " "unprognostic (1.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PSMA1 "HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30" ENSG00000129084 "Proteasome subunit alpha 1" P25786 11 14504874-14643635 "Enzymes, Predicted intracellular proteins" Immunity "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB033765, HPA037646, HPA043891" Supported Enhanced Nucleoplasm 27000000 Nucleoplasm "CAB033765: AB_2253026, HPA037646: AB_10670386, HPA043891: AB_2678718" "unprognostic (1.72e-2)" "unprognostic (4.97e-2)" "unprognostic (7.33e-2)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (6.66e-3)" "prognostic unfavourable (3.79e-5)" "unprognostic (3.28e-3)" "unprognostic (7.44e-2)" "unprognostic (3.43e-3)" "unprognostic (8.27e-3)" "unprognostic (8.77e-2)" "prognostic unfavourable (4.03e-11)" "unprognostic (1.93e-1)" "unprognostic (1.69e-1)" "unprognostic (4.66e-2)" "unprognostic (1.23e-2)" 46.6 46.3 33.7 36.0 40.2 45.7 39.0 28.3 42.7 33.4 35.5 23.1 37.4 37.3 42.1 43.1 43.7 33.0 32.2 55.4 31.7 34.1 47.8 61.0 38.8 42.3 32.0 32.4 34.0 35.6 28.2 39.4 55.2 36.9 35.6 42.4 32.9 34.9 37.1 86.6 35.3 42.7 39.0 26.7 45.8 37.3 31.6 25.9 53.0 45.5 62.8 42.2 41.5 31.7 24.2 55.4 20.9 42.3 30.5 35.7 45.2 66.1 46.8 39.2 46.9 39.1 39.4 32.7 39.1 51.5 59.7 49.1 40.5 83.6 57.9 43.4 41.3 49.9 44.7 48.5 56.6 56.2 66.4 36.1 31.1 47.8 51.4 59.8 47.2 38.2 28.9 32.4 67.8 58.4 67.6 48.8 53.0 43.9 54.4 45.0 32.7 69.8 36.9 58.1 35.9 51.9 46.9 32.4 20.4 41.7 46.8 34.9 27.9 36.6 46.1 39.1 36.8 68.4 47.8 21.4 57.2 51.8 57.8 47.7 49.9 20.9 42.3 11.0 24.3 31.1 32.3 24.2 28.3 27.2 55.4 20.6 25.7 25.0 9.4 30.5 29.4 31.3 35.7 45.2 33.7 40.2 28.3 42.7 31.7 34.1 32.0 32.4 36.9 25.9 PSMA2 "HC3, MU, PMSA2" ENSG00000106588 "Proteasome subunit alpha 2" P25787 7 42916857-42932223 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA008188 Uncertain 80000000 "HPA008188: AB_1855819" "unprognostic (9.40e-3)" "unprognostic (2.08e-2)" "unprognostic (8.21e-2)" "unprognostic (2.23e-2)" "unprognostic (4.13e-2)" "unprognostic (1.90e-1)" "prognostic unfavourable (1.29e-4)" "unprognostic (2.01e-2)" "unprognostic (9.25e-2)" "prognostic favourable (6.73e-5)" "unprognostic (1.77e-1)" "unprognostic (3.42e-1)" "unprognostic (1.62e-3)" "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (6.38e-2)" "unprognostic (4.24e-2)" 24.7 32.2 25.3 24.6 29.5 29.7 29.4 19.6 22.0 19.2 25.6 13.4 26.0 29.8 22.6 26.2 31.1 19.4 20.5 35.8 22.3 16.6 33.3 90.9 23.2 27.4 27.2 17.6 20.8 28.8 12.0 18.8 33.7 29.2 24.5 26.0 10.1 21.7 19.6 57.2 22.4 33.1 22.0 21.4 26.6 27.8 18.6 23.5 42.2 29.9 44.6 29.9 22.8 20.2 46.2 54.1 81.7 47.4 36.7 56.7 75.0 31.9 34.3 40.3 48.6 21.5 24.2 30.1 28.2 33.1 45.7 49.0 51.0 52.6 59.4 50.5 25.0 44.7 41.5 39.2 52.7 42.9 33.0 30.2 46.5 53.8 23.0 51.3 32.8 22.2 28.6 35.2 21.0 42.9 60.9 36.5 36.5 37.4 45.7 100.9 79.7 42.6 44.7 39.2 58.3 43.9 44.1 32.8 33.3 30.7 70.6 30.9 51.4 60.1 30.6 27.1 49.4 29.0 55.6 47.6 72.1 97.2 46.1 65.2 76.5 59.0 45.7 81.7 35.2 45.2 40.4 46.2 43.4 40.5 48.5 40.7 39.0 41.3 23.3 36.7 47.4 54.1 56.7 75.0 25.3 29.5 19.6 22.0 22.3 16.6 27.2 17.6 29.2 23.5 PSMA3 HC8 ENSG00000100567 "Proteasome subunit alpha 3" P25788 14 58244831-58272012 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000905 Approved 13000000 "HPA000905: AB_1079702" "unprognostic (3.60e-1)" "unprognostic (4.81e-3)" "unprognostic (1.17e-1)" "unprognostic (2.19e-2)" "unprognostic (4.91e-1)" "unprognostic (5.79e-2)" "unprognostic (1.97e-3)" "unprognostic (1.27e-1)" "unprognostic (7.92e-2)" "unprognostic (7.36e-3)" "unprognostic (1.65e-2)" "unprognostic (7.57e-2)" "unprognostic (1.83e-3)" "unprognostic (2.33e-2)" "unprognostic (6.47e-2)" "prognostic favourable (2.91e-4)" "unprognostic (2.16e-1)" 26.6 41.5 21.3 27.7 25.0 24.3 28.7 16.2 25.1 23.3 26.5 17.5 34.3 27.7 25.4 46.3 33.5 23.4 21.1 55.8 24.2 22.6 51.2 59.6 28.0 31.9 23.2 20.3 23.5 25.1 20.0 30.8 50.6 28.3 24.7 28.9 17.5 25.0 27.7 68.6 18.1 34.4 27.0 22.4 33.9 26.9 15.9 15.8 32.5 37.6 50.6 31.2 32.0 20.5 36.1 50.7 31.2 40.3 38.0 45.9 36.1 66.5 41.5 41.3 33.9 32.5 30.5 53.2 35.2 39.5 49.4 49.7 61.3 55.4 56.1 65.5 31.8 45.9 47.0 37.6 58.1 49.2 28.8 38.4 31.4 69.1 61.7 61.8 33.0 26.0 27.2 34.3 32.7 58.0 36.3 33.2 39.6 75.8 53.9 59.8 28.0 63.0 45.8 53.6 41.5 71.2 65.9 39.0 19.5 31.3 49.8 34.3 51.9 46.4 37.1 28.9 56.4 32.5 47.0 13.4 25.0 57.9 41.6 48.6 34.8 31.2 34.3 20.6 32.4 40.3 40.6 36.1 39.7 38.1 37.9 25.6 32.4 37.2 20.1 38.0 33.7 50.7 45.9 36.1 21.3 25.0 16.2 25.1 24.2 22.6 23.2 20.3 28.3 15.8 PSMA4 "HC9, HsT17706" ENSG00000041357 "Proteasome subunit alpha 4" P25789 15 78540405-78552419 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004973, HPA055466, HPA060613" Supported Supported Nucleoplasm,Vesicles,Cytosol 12000000 "Nucleoplasm, Cytosol" Vesicles "CAB004973: AB_425627, HPA055466: , HPA060613: " "unprognostic (1.80e-1)" "unprognostic (7.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (4.71e-2)" "unprognostic (5.35e-2)" "unprognostic (6.26e-3)" "unprognostic (1.09e-1)" "unprognostic (3.28e-2)" "unprognostic (2.08e-3)" "unprognostic (2.75e-3)" "unprognostic (1.26e-1)" "prognostic unfavourable (6.74e-10)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (3.78e-3)" "unprognostic (6.32e-3)" 41.2 38.8 24.9 36.7 25.8 33.4 33.0 25.3 37.5 32.4 38.0 17.9 23.7 39.4 35.3 32.5 49.9 27.1 24.4 37.7 29.8 27.6 55.7 76.3 37.4 45.1 25.5 26.9 31.2 24.4 20.2 25.9 55.4 33.8 35.3 41.3 19.1 26.0 25.0 60.3 26.3 49.1 36.6 28.1 45.5 31.5 36.5 21.4 61.6 42.6 75.0 44.8 41.3 28.3 29.4 61.9 31.4 75.6 37.7 40.0 61.4 40.1 58.2 50.4 44.4 31.8 30.1 39.5 37.8 30.4 46.6 50.0 60.5 58.7 87.7 55.9 34.8 55.0 101.6 41.0 45.1 35.9 70.8 73.6 43.6 48.7 51.6 74.8 45.5 24.3 25.7 39.2 39.1 50.2 78.9 34.4 38.0 57.8 50.4 70.2 47.4 34.2 43.9 66.7 29.4 47.2 70.4 44.5 32.5 60.6 44.3 46.1 40.9 61.6 39.9 34.8 46.5 38.3 64.3 31.5 74.2 82.7 32.6 112.5 38.3 18.8 47.4 31.4 27.8 75.6 28.5 29.4 29.2 29.0 61.9 22.9 23.3 28.3 21.7 37.7 69.7 35.3 40.0 61.4 24.9 25.8 25.3 37.5 29.8 27.6 25.5 26.9 33.8 21.4 PSMA5 ZETA ENSG00000143106 "Proteasome subunit alpha 5" P28066 1 109399031-109426427 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028392, HPA028398, HPA028441" Approved Supported Cytosol 22000000 Cytosol "HPA028392: AB_10600115, HPA028398: AB_10602310, HPA028441: AB_10602003" "unprognostic (3.82e-2)" "unprognostic (3.09e-3)" "prognostic favourable (1.45e-5)" "unprognostic (1.57e-1)" "unprognostic (2.71e-1)" "unprognostic (1.52e-2)" "prognostic unfavourable (2.28e-4)" "unprognostic (5.95e-2)" "unprognostic (1.71e-2)" "unprognostic (1.13e-3)" "unprognostic (4.20e-3)" "unprognostic (3.05e-1)" "unprognostic (1.07e-3)" "unprognostic (3.99e-2)" "unprognostic (2.34e-1)" "unprognostic (8.81e-3)" "unprognostic (1.05e-1)" 12.1 23.7 13.2 17.3 15.0 7.7 16.2 8.2 40.5 13.3 16.1 9.8 16.7 15.1 15.8 23.0 21.5 17.6 16.7 20.8 13.8 13.5 27.5 41.9 17.1 24.2 13.4 14.9 13.6 21.4 12.6 11.5 20.9 12.8 12.3 14.9 10.2 16.8 14.2 31.6 15.8 21.8 14.4 12.9 18.5 15.2 16.3 10.3 31.5 27.9 23.4 19.8 14.0 11.7 2.1 1.2 7.3 2.2 2.8 7.1 1.6 1.2 1.0 1.6 1.2 3.8 4.1 1.4 0.9 9.1 6.0 3.5 1.2 1.1 5.2 1.2 4.0 1.6 2.3 3.1 3.7 1.1 1.5 2.2 0.9 1.5 2.9 2.9 1.2 1.9 3.0 1.8 3.0 2.2 1.8 1.4 2.5 1.5 30.5 1.2 1.4 1.5 0.8 3.1 0.8 4.8 1.6 1.4 1.1 1.6 5.4 1.9 1.2 2.6 1.4 1.0 0.7 2.1 1.2 0.8 1.8 6.6 6.6 6.6 1.0 7.3 1.0 0.7 4.0 2.2 4.8 1.8 5.8 4.9 1.2 2.1 7.1 6.5 0.3 2.8 2.0 0.8 5.3 1.6 13.2 15.0 8.2 17.5 13.8 13.5 13.4 14.9 12.8 10.3 PSMA6 "IOTA, MGC22756, MGC2333, MGC23846, p27K, PROS27" ENSG00000100902 "Proteasome subunit alpha 6" P60900 14 35278633-35317493 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003049 Approved Supported Nucleoplasm 19000000 Nucleoplasm "HPA003049: AB_1079703" "unprognostic (9.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.90e-2)" "unprognostic (8.07e-2)" "unprognostic (3.42e-2)" "unprognostic (4.11e-3)" "unprognostic (7.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "prognostic favourable (3.27e-4)" "unprognostic (1.29e-3)" "unprognostic (2.63e-1)" "unprognostic (1.52e-2)" "unprognostic (2.05e-1)" "unprognostic (5.45e-2)" "unprognostic (3.49e-1)" "unprognostic (5.08e-2)" 33.8 42.7 26.7 31.4 38.8 37.1 38.7 24.2 35.0 28.0 35.8 19.4 24.5 32.2 31.0 30.2 37.9 24.7 20.3 54.2 30.5 27.6 47.3 49.0 37.3 36.4 30.1 36.8 31.1 36.7 14.2 35.8 61.2 31.8 22.5 38.6 18.1 27.3 25.5 94.6 31.8 39.5 27.3 25.2 35.7 28.9 67.5 26.5 86.2 26.0 37.2 38.1 28.8 24.5 37.9 68.5 41.4 65.1 49.9 54.8 104.8 58.9 43.6 32.7 33.2 27.0 28.8 65.4 30.9 37.8 46.8 42.6 40.6 42.8 39.5 59.5 30.0 42.3 38.1 35.3 56.1 39.7 20.8 31.0 31.8 121.4 30.6 64.5 29.0 21.9 29.4 32.7 41.7 39.6 33.1 27.7 37.8 62.6 98.6 55.1 31.2 49.7 147.1 33.2 31.6 40.0 75.8 34.8 29.4 34.5 50.8 32.5 60.8 42.7 32.9 30.2 29.8 30.7 34.2 29.5 64.6 72.2 24.5 40.9 34.0 32.8 65.1 41.4 46.3 59.4 46.2 37.9 44.8 47.1 66.8 29.9 35.9 43.0 23.5 49.9 56.6 68.5 54.8 104.8 26.7 38.8 24.2 35.0 30.5 27.6 30.1 36.8 31.8 26.5 PSMA7 "C6, HSPC, RC6-1, XAPC7" ENSG00000101182 "Proteasome subunit alpha 7" O14818 20 62136735-62143440 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046007, CAB046008, HPA047266" Approved 26000000 "CAB046007: AB_11128404, CAB046008: AB_2171861, HPA047266: " "unprognostic (1.49e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-1)" "unprognostic (6.57e-3)" "prognostic unfavourable (2.54e-5)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (5.06e-3)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (7.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.21e-2)" "unprognostic (6.31e-2)" "unprognostic (1.98e-2)" 45.1 40.2 26.5 35.0 28.0 56.1 53.1 23.8 30.7 23.2 34.2 21.1 25.4 32.1 33.3 26.6 36.6 26.4 27.3 64.7 26.3 25.7 36.0 63.6 32.8 36.0 28.4 27.0 28.0 48.0 17.1 21.5 27.9 25.0 27.7 27.6 20.7 25.7 27.7 130.5 26.2 33.1 36.9 24.7 34.8 29.7 16.1 22.6 37.2 33.0 53.4 36.8 36.1 44.0 92.3 112.0 124.4 111.2 64.3 114.6 153.5 56.2 69.9 43.1 44.8 39.8 30.6 39.8 44.2 36.2 108.9 46.0 183.0 53.0 46.8 103.1 44.3 67.6 40.2 78.4 54.3 29.3 31.0 104.9 70.5 92.3 49.4 44.6 61.6 32.7 64.1 56.2 50.0 53.9 46.0 44.8 47.2 57.7 71.5 71.3 36.2 101.1 49.9 81.3 50.7 41.6 53.1 58.1 35.7 66.5 82.6 71.1 49.6 67.6 43.8 96.9 79.9 50.9 65.7 32.1 49.3 55.1 67.6 34.3 56.3 98.4 111.2 124.4 93.3 109.7 79.2 92.3 93.7 92.0 102.8 83.7 74.7 77.5 94.4 64.3 109.7 112.0 114.6 153.5 26.5 28.0 23.8 30.7 26.3 25.7 28.4 27.0 25.0 22.6 PSMB1 "HC5, PMSB1" ENSG00000008018 "Proteasome subunit beta 1" P20618 6 170535117-170553341 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029635, HPA029637, CAB033911" Enhanced Supported Nucleoplasm 14000000 Nucleoplasm "CAB033911: AB_2268890, HPA029635: AB_10599738, HPA029637: AB_10601793" "unprognostic (2.78e-2)" "unprognostic (3.10e-2)" "unprognostic (6.73e-2)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (5.41e-3)" "unprognostic (2.36e-2)" "unprognostic (3.32e-2)" "unprognostic (8.39e-2)" "unprognostic (4.28e-2)" "unprognostic (3.07e-1)" "unprognostic (1.09e-1)" "prognostic unfavourable (3.76e-6)" "unprognostic (3.63e-1)" "unprognostic (7.50e-2)" "unprognostic (1.45e-3)" "unprognostic (9.62e-2)" 60.8 59.3 38.5 40.4 53.7 53.2 55.0 31.4 46.4 40.5 48.6 37.9 49.9 45.1 56.8 90.6 51.7 49.8 43.1 71.9 40.9 40.1 56.4 93.2 46.9 66.7 40.8 41.1 43.7 67.3 35.4 48.4 80.6 48.4 40.6 52.7 43.8 43.6 50.0 109.3 56.1 46.0 59.7 44.9 51.4 46.9 47.1 38.1 47.1 47.9 75.2 60.4 50.1 42.0 71.0 98.1 51.9 81.9 71.6 79.3 104.1 42.5 40.0 57.1 73.6 51.1 40.2 60.8 40.8 60.0 68.0 69.6 87.5 36.8 62.3 53.2 54.5 43.1 63.3 64.8 71.0 63.4 71.2 53.2 40.6 109.7 60.0 62.4 47.5 45.8 39.9 65.6 42.6 58.0 105.0 53.5 62.0 114.6 46.7 87.1 52.1 55.1 45.2 45.3 79.0 70.5 25.6 57.1 46.6 39.2 60.9 31.2 41.7 90.4 44.1 27.7 44.5 67.3 75.3 45.8 60.6 77.4 64.7 70.7 59.4 40.1 81.9 51.9 53.2 75.8 62.1 71.0 62.2 57.7 98.1 53.4 59.2 57.2 47.5 71.6 67.6 55.8 79.3 104.1 38.5 53.7 31.4 46.4 40.9 40.1 40.8 41.1 48.4 38.1 PSMB10 "beta2i, LMP10, MECL1, MGC1665" ENSG00000205220 "Proteasome subunit beta 10" P40306 16 67934502-67937087 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 117.3" "Cell line enhanced" "Detected in many" "REH: 36.0;U-266/70: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA030224, HPA030225, CAB034384" Enhanced Supported Vesicles,Cytosol 1400000 Cytosol Vesicles "CAB034384: AB_2171876, HPA030224: , HPA030225: AB_10603231" "unprognostic (1.18e-2)" "unprognostic (1.90e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-3)" "unprognostic (2.00e-1)" "unprognostic (1.85e-2)" "unprognostic (7.22e-2)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-1)" "unprognostic (8.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.32e-2)" "unprognostic (2.97e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-2)" "prognostic favourable (5.44e-4)" 11.5 13.0 9.1 24.9 11.8 23.9 11.4 4.0 7.8 8.0 21.6 5.6 8.5 42.4 9.3 9.5 10.6 12.4 16.6 12.0 6.9 4.9 16.9 17.2 19.5 38.3 9.5 5.6 8.7 61.5 0.9 6.9 11.2 8.5 13.5 6.3 5.8 27.9 11.6 6.9 7.0 35.6 7.7 6.5 49.7 23.8 2.5 7.8 39.2 13.1 10.4 20.5 13.2 8.4 50.8 75.2 100.0 98.1 69.1 68.8 117.3 5.9 5.3 0.4 0.8 0.4 3.5 21.0 2.0 8.5 6.9 9.8 2.7 29.1 21.6 3.7 2.7 8.7 0.1 1.9 0.5 9.6 0.5 7.7 1.8 3.0 12.0 14.3 23.6 5.3 1.2 3.0 0.0 4.0 0.7 8.3 1.9 7.4 28.1 14.7 0.3 2.0 36.0 2.2 29.5 4.7 10.4 0.3 0.4 6.7 11.8 2.6 2.4 31.0 6.7 4.4 1.2 1.9 2.3 40.3 7.2 14.4 10.9 18.7 9.5 57.1 89.4 67.1 68.8 98.1 50.2 50.8 54.0 57.3 74.6 49.1 45.3 50.1 100.0 69.1 71.4 75.2 60.8 117.3 9.1 11.8 4.0 7.8 6.9 4.9 9.5 5.6 8.5 7.8 PSMB11 beta5t ENSG00000222028 "Proteasome subunit beta 11" A5LHX3 14 23042167-23044276 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 32.7" "Cell line enriched" "Detected in single" 4 "PC-3: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 21 "T-cells: 2.1" "Region enriched" "Detected in single" 7 "olfactory region: 2.3" "Not detected" "Not detected" "HPA028967, HPA056970" Enhanced "HPA028967: AB_2732444, HPA056970: AB_2683293" "unprognostic (7.96e-2)" "unprognostic (2.77e-1)" 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 32.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 PSMB2 HC7-I ENSG00000126067 "Proteasome subunit beta 2" P49721 1 35599544-35641844 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026322, HPA026324" Approved Enhanced Nucleoplasm 15000000 Nucleoplasm "HPA026322: AB_1855821, HPA026324: AB_1855822" "unprognostic (3.54e-2)" "unprognostic (8.53e-2)" "unprognostic (1.63e-3)" "unprognostic (6.93e-2)" "unprognostic (6.41e-2)" "unprognostic (1.37e-1)" "prognostic unfavourable (3.49e-7)" "unprognostic (2.81e-2)" "unprognostic (5.23e-2)" "unprognostic (3.34e-3)" "unprognostic (7.87e-2)" "unprognostic (4.45e-1)" "prognostic unfavourable (2.80e-6)" "unprognostic (1.65e-1)" "unprognostic (2.83e-1)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" 26.5 30.5 29.4 28.0 35.1 37.2 25.3 20.1 50.9 23.2 26.1 35.9 15.4 27.5 27.8 25.0 30.4 26.5 20.7 23.8 30.6 33.4 27.9 63.8 24.6 30.4 30.6 24.8 22.7 24.6 22.0 21.8 37.5 32.6 23.1 27.8 22.8 23.0 24.9 54.7 28.2 27.0 28.7 32.5 29.3 22.8 23.5 21.5 42.8 22.7 29.1 34.0 23.9 22.4 24.6 30.2 19.4 35.3 25.1 28.1 25.4 40.6 25.5 27.8 19.0 14.8 17.8 35.2 19.3 22.7 39.8 32.5 30.2 48.9 40.6 45.3 22.7 25.3 35.8 32.0 33.5 33.1 33.2 36.8 27.9 29.5 26.7 38.6 21.7 19.4 20.3 47.5 23.1 31.2 43.9 23.2 25.6 18.7 50.2 28.9 37.2 27.1 31.1 28.4 28.6 27.6 22.0 24.7 18.2 22.1 20.9 29.8 15.4 17.6 21.5 19.9 23.5 18.8 45.5 20.0 32.2 41.1 29.5 40.7 34.5 17.4 27.0 19.4 23.1 33.0 23.4 24.6 23.1 24.2 29.7 19.3 16.7 20.9 9.7 25.1 35.3 30.2 28.1 25.4 29.4 35.1 20.1 50.9 30.6 33.4 30.6 24.8 32.6 21.5 PSMB3 "HC10-II, MGC4147" ENSG00000277791 "Proteasome subunit beta 3" P49720 17 38752736-38764231 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 99.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042775, HPA048147" Approved 28000000 "HPA042775: , HPA048147: " "unprognostic (1.86e-1)" "unprognostic (4.84e-3)" "unprognostic (1.44e-1)" "unprognostic (4.80e-2)" "unprognostic (6.68e-2)" "unprognostic (1.14e-3)" "unprognostic (5.46e-2)" "unprognostic (2.46e-2)" "unprognostic (2.02e-1)" "unprognostic (1.75e-2)" "unprognostic (3.65e-1)" "unprognostic (1.13e-1)" "prognostic unfavourable (1.71e-6)" "unprognostic (4.44e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-3)" "unprognostic (6.03e-2)" 13.3 9.6 5.2 9.9 8.6 13.3 10.3 3.0 13.9 8.5 11.8 7.5 6.4 9.2 5.6 15.3 14.7 10.3 9.8 15.6 4.4 21.6 36.8 11.6 13.0 8.4 7.1 9.6 11.3 7.3 5.7 17.2 8.5 10.8 12.0 9.1 8.5 10.0 22.2 10.0 14.1 11.0 4.7 17.5 7.2 8.5 7.0 23.3 16.7 12.2 15.6 10.2 5.6 32.7 55.0 99.0 56.5 29.1 43.1 63.7 27.7 52.2 21.7 33.5 24.1 19.0 27.7 18.3 31.1 64.4 56.8 62.4 36.1 31.9 33.0 27.3 47.9 35.8 35.4 39.9 41.7 62.8 20.5 30.3 64.7 12.0 32.8 31.6 19.8 21.9 48.4 16.4 34.7 33.0 36.3 31.0 36.3 51.0 51.1 29.3 39.0 28.9 43.9 50.0 37.5 28.4 26.8 17.7 23.5 17.8 22.7 41.0 38.2 18.3 16.9 31.2 35.9 46.7 23.7 40.3 41.3 33.5 32.5 29.6 41.1 56.5 47.4 30.3 49.7 27.9 32.7 28.5 27.6 55.0 28.1 23.0 24.8 99.0 29.1 39.9 53.2 43.1 63.7 PSMB4 "HN3, PROS26" ENSG00000159377 "Proteasome subunit beta 4" P28070 1 151399534-151401944 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006700 Approved 15000000 "HPA006700: AB_1079704" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (2.69e-1)" "unprognostic (2.52e-1)" "unprognostic (1.63e-1)" "unprognostic (5.74e-2)" "prognostic unfavourable (7.45e-4)" "unprognostic (2.27e-1)" "unprognostic (1.69e-1)" "unprognostic (4.37e-3)" "unprognostic (3.73e-1)" "unprognostic (3.77e-1)" "prognostic unfavourable (2.90e-10)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (3.82e-2)" "unprognostic (5.85e-2)" 45.7 64.5 47.4 40.4 49.5 40.2 56.3 39.6 84.0 44.4 44.3 28.5 58.8 41.2 53.5 65.3 55.7 51.2 37.8 66.6 47.0 50.7 57.3 71.9 43.6 81.1 49.2 61.0 52.4 87.0 40.0 45.4 50.9 48.4 42.6 47.5 37.8 46.7 56.1 68.7 45.7 39.7 66.4 55.1 46.6 43.4 31.8 36.3 51.1 46.8 63.3 62.2 58.6 37.7 68.5 106.5 58.6 81.4 72.5 89.0 78.3 51.2 53.8 45.8 54.9 51.9 49.5 63.0 30.2 66.1 88.3 62.0 71.9 69.3 46.7 91.8 50.6 51.5 46.4 56.9 50.5 65.1 47.0 32.3 40.3 53.8 56.1 44.9 44.4 54.0 54.4 83.0 34.1 61.6 52.1 91.4 62.2 137.3 53.9 52.9 117.2 69.7 51.7 33.5 82.4 72.2 41.9 50.9 60.5 35.2 76.9 101.2 69.5 71.2 39.0 38.8 41.3 41.2 66.4 91.1 104.3 90.0 57.3 40.0 81.6 54.6 81.4 49.5 63.9 75.2 75.9 68.5 74.9 72.5 96.4 60.8 65.8 68.0 58.6 72.5 56.9 106.5 89.0 78.3 47.4 49.5 39.6 84.0 47.0 50.7 49.2 61.0 48.4 36.3 PSMB5 "MB1, X" ENSG00000100804 "Proteasome subunit beta 5" P28074 14 23016543-23035230 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049518, HPA061796" Approved Supported Nucleoplasm,Centrosome 8200000 "Nucleoplasm, Centrosome" "HPA049518: , HPA061796: " "unprognostic (3.03e-1)" "unprognostic (1.99e-2)" "unprognostic (8.35e-2)" "unprognostic (6.13e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (2.85e-4)" "prognostic unfavourable (2.90e-5)" "unprognostic (2.55e-2)" "unprognostic (9.95e-2)" "prognostic favourable (1.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.19e-1)" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (1.95e-1)" "unprognostic (4.95e-2)" "prognostic unfavourable (4.73e-4)" 28.1 38.8 33.6 19.3 35.5 9.6 29.0 19.4 42.9 24.7 28.3 26.8 25.4 21.0 24.2 49.2 31.6 31.6 22.0 37.7 32.9 33.3 35.3 45.4 20.6 18.3 37.5 35.4 22.2 36.6 35.4 26.6 32.5 33.9 27.2 32.2 21.1 28.4 28.7 101.2 22.3 17.2 34.9 32.5 16.7 25.1 27.6 27.3 15.7 29.0 47.3 22.7 20.6 25.2 32.3 53.4 24.6 39.9 19.4 46.8 39.5 22.1 47.1 33.7 31.9 45.4 39.2 33.3 31.6 37.6 55.8 47.4 39.6 35.2 27.5 29.5 42.9 30.2 53.8 39.4 53.9 16.8 37.2 17.4 34.4 139.6 35.9 21.1 21.0 43.7 37.0 41.3 34.5 57.6 26.2 15.6 45.6 65.1 12.0 29.0 37.4 76.4 16.2 25.4 18.3 43.3 32.1 43.0 33.5 22.2 45.2 30.3 21.8 27.5 30.9 27.3 27.8 25.2 31.0 13.5 26.8 20.6 21.3 17.1 33.8 24.6 39.9 17.3 29.3 39.0 34.2 32.3 35.1 28.1 42.6 30.1 46.8 35.6 15.5 19.4 27.9 53.4 28.7 39.5 33.6 35.5 19.4 42.9 32.9 33.3 37.5 35.4 33.9 27.3 PSMB6 "DELTA, Y" ENSG00000142507 "Proteasome subunit beta 6" P28072 17 4796144-4798503 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023312, HPA063656" Supported Supported Nucleoplasm,Cytosol 2800000 Nucleoplasm Cytosol "HPA023312: AB_1855828, HPA063656: " "unprognostic (2.71e-1)" "unprognostic (1.86e-2)" "unprognostic (2.75e-1)" "unprognostic (3.32e-3)" "unprognostic (8.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-2)" "unprognostic (7.47e-2)" "prognostic unfavourable (5.93e-4)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (5.27e-2)" "unprognostic (5.66e-2)" 28.6 35.0 33.7 23.2 36.4 31.7 34.0 24.2 41.5 29.6 31.7 26.7 26.8 22.6 33.4 47.1 41.9 30.3 24.2 72.0 30.4 30.5 41.4 67.1 25.7 35.3 33.4 34.0 25.3 41.8 40.8 26.6 49.6 35.9 26.4 36.1 23.5 30.6 36.6 97.4 33.6 23.2 40.5 29.7 29.0 31.2 27.0 28.0 35.8 34.6 53.8 39.6 27.9 26.0 93.9 96.3 51.1 95.3 60.4 81.2 107.9 46.0 80.6 43.5 37.1 37.1 33.4 50.2 24.4 51.1 74.7 58.6 59.9 37.6 35.8 48.5 58.4 46.7 66.1 68.4 72.9 46.6 69.7 21.2 53.0 69.6 42.8 21.9 33.9 31.5 52.5 65.2 62.1 72.5 32.4 54.5 57.2 54.8 38.7 36.6 36.9 56.0 43.4 30.9 47.4 56.0 31.1 25.5 31.3 35.0 27.4 25.1 33.4 24.6 34.5 36.9 27.9 49.5 59.0 22.8 30.3 21.8 52.8 40.1 44.3 51.1 95.3 50.5 57.1 87.5 57.8 93.9 62.3 62.6 96.3 79.8 53.7 56.1 32.9 60.4 78.0 89.7 81.2 107.9 33.7 36.4 24.2 41.5 30.4 30.5 33.4 34.0 35.9 28.0 PSMB7 ENSG00000136930 "Proteasome subunit beta 7" Q99436 9 124353466-124415444 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052408, HPA054902" Supported Supported Nucleoplasm,Cytosol 2700000 Nucleoplasm Cytosol "HPA052408: , HPA054902: " "unprognostic (7.75e-2)" "unprognostic (1.83e-2)" "unprognostic (1.27e-1)" "unprognostic (3.64e-3)" "unprognostic (2.83e-1)" "unprognostic (1.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.24e-3)" "unprognostic (9.03e-2)" "unprognostic (3.60e-1)" "unprognostic (2.99e-1)" "unprognostic (1.78e-1)" "unprognostic (1.26e-2)" "unprognostic (1.67e-1)" "unprognostic (3.45e-1)" "unprognostic (1.93e-3)" "unprognostic (3.98e-2)" 36.9 56.9 51.0 32.8 55.1 53.4 41.9 33.7 52.7 26.6 33.3 34.0 27.9 32.5 33.6 52.1 41.9 32.6 29.2 59.6 44.5 41.3 53.7 87.1 27.0 33.6 43.6 46.9 32.7 67.1 38.5 24.1 53.2 47.3 28.8 37.1 31.1 48.2 26.9 76.7 48.7 32.2 31.4 39.9 28.6 33.1 50.3 36.5 48.2 32.7 67.7 39.5 32.3 30.8 53.4 67.9 45.2 62.7 53.6 66.2 69.0 51.9 63.5 43.5 52.5 30.7 36.7 62.7 50.6 69.8 73.4 50.7 83.4 50.8 59.3 40.9 47.3 74.4 54.1 53.6 67.4 57.0 46.7 37.1 101.0 69.2 69.5 73.6 37.1 43.9 47.3 76.4 76.6 61.5 75.7 42.2 56.6 90.4 52.8 49.5 64.3 90.9 46.8 64.9 69.3 51.9 34.0 51.3 41.8 48.1 61.7 74.9 71.1 32.4 48.7 47.5 38.3 60.6 75.7 45.8 128.3 59.8 79.4 45.4 66.7 40.4 61.7 45.2 41.8 62.7 45.0 53.4 48.1 46.1 67.9 47.5 46.3 44.9 27.3 53.6 58.4 57.8 66.2 69.0 51.0 55.1 33.7 52.7 44.5 41.3 43.6 46.9 47.3 36.5 PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome subunit beta 8" P28062 6 32840717-32844703 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" 3300000 Vesicles "Cytokinetic bridge" "HPA046995: AB_2679896, HPA050327: AB_2681088" "prognostic favourable (5.08e-4)" "unprognostic (4.22e-2)" "unprognostic (2.39e-2)" "prognostic favourable (7.16e-4)" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (7.78e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-3)" "unprognostic (7.11e-3)" 17.0 21.9 7.9 34.8 11.7 14.0 14.9 3.6 7.5 10.0 20.8 5.1 8.8 20.1 12.5 15.3 16.6 13.2 23.8 10.6 6.6 5.7 20.9 30.0 29.0 46.3 9.9 5.1 11.3 12.7 3.6 8.2 9.7 8.8 13.5 24.4 9.2 14.6 11.2 5.1 14.7 37.3 11.5 9.0 42.8 19.4 3.9 9.0 32.2 18.7 18.7 29.0 13.9 12.5 28.9 27.4 37.6 33.2 23.3 29.9 52.2 6.3 2.0 0.1 0.0 2.7 7.0 4.4 1.5 10.1 12.4 17.9 0.0 11.2 24.8 4.8 4.1 4.5 1.4 6.0 3.4 10.2 0.0 10.9 1.3 0.4 14.8 0.2 4.1 7.9 2.8 6.9 2.3 8.4 0.3 5.2 3.1 0.0 5.7 6.0 0.0 1.6 15.5 0.8 12.2 10.1 1.8 0.1 0.1 2.2 5.3 3.3 2.4 20.3 2.5 3.7 1.9 3.5 0.2 8.8 8.3 5.5 1.3 14.3 4.6 19.4 29.0 37.4 25.5 33.2 22.1 28.9 21.7 26.4 27.4 26.3 15.1 21.6 37.6 23.3 28.6 23.3 29.9 52.2 7.9 11.7 3.6 7.5 6.6 5.7 9.9 5.1 8.8 9.0 PSMB9 "beta1i, LMP2, PSMB6i, RING12" ENSG00000240065 "Proteasome subunit beta 9" P28065 6 32844136-32859585 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 69.1;lymphoid tissue: 54.9" "Cell line enhanced" "Detected in many" "Daudi: 29.1;REH: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB015180, HPA042818, HPA053280" Enhanced Supported Cytosol 420000 Cytosol "CAB015180: AB_2172368, HPA042818: , HPA053280: " "unprognostic (1.09e-2)" "unprognostic (1.68e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-3)" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (5.68e-2)" "unprognostic (6.67e-2)" "unprognostic (1.56e-2)" "unprognostic (6.50e-3)" "unprognostic (1.87e-3)" "unprognostic (1.84e-1)" "prognostic unfavourable (1.33e-4)" "unprognostic (2.65e-1)" "unprognostic (1.09e-1)" "unprognostic (4.96e-3)" "unprognostic (5.99e-2)" 13.3 9.7 5.0 30.0 7.9 10.7 11.6 1.6 5.3 7.6 16.5 6.0 3.4 15.7 8.8 7.1 10.8 7.4 10.8 8.9 5.1 4.7 12.2 12.2 17.7 32.7 7.3 3.7 9.2 5.4 1.2 4.5 5.5 6.3 12.5 5.8 7.7 9.0 3.5 6.2 7.6 36.1 5.7 9.8 54.9 11.2 3.0 6.7 35.4 14.4 9.3 35.2 15.9 8.8 31.8 17.2 69.1 30.5 23.4 31.1 45.7 0.0 1.4 0.0 0.1 1.1 2.9 2.0 0.2 3.2 4.2 9.7 0.0 9.1 29.1 0.4 2.6 5.9 0.4 6.2 0.5 16.4 0.0 17.7 0.5 1.1 15.7 3.1 1.3 1.3 0.2 2.6 0.4 1.5 0.7 5.4 1.4 0.4 13.4 4.1 0.0 0.9 21.5 0.0 6.9 2.8 0.5 0.0 0.0 2.7 1.7 1.9 2.3 6.5 1.5 4.5 0.4 8.5 2.5 10.1 15.3 9.3 4.6 11.8 3.8 21.9 22.4 39.3 28.7 30.5 23.8 31.8 23.3 27.5 17.2 23.4 17.5 22.9 69.1 23.4 29.4 12.7 31.1 45.7 5.0 7.9 1.6 5.3 5.1 4.7 7.3 3.7 6.3 6.7 PSMD14 "pad1, POH1, Rpn11" ENSG00000115233 "Proteasome 26S subunit, non-ATPase 14" O00487 2 161308038-161411717 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002114, HPA003828" Approved Supported Nucleoplasm 9400 Nucleoplasm "HPA002114: AB_1855850, HPA003828: " "unprognostic (3.50e-3)" "unprognostic (1.48e-1)" "unprognostic (9.61e-2)" "unprognostic (6.63e-2)" "unprognostic (2.57e-1)" "unprognostic (7.61e-3)" "prognostic unfavourable (2.66e-8)" "unprognostic (3.11e-2)" "unprognostic (4.04e-2)" "unprognostic (3.90e-3)" "unprognostic (9.84e-3)" "unprognostic (3.02e-1)" "prognostic unfavourable (3.10e-6)" "unprognostic (2.86e-2)" "unprognostic (4.70e-2)" "unprognostic (3.54e-1)" "unprognostic (1.66e-1)" 18.2 26.3 24.8 19.9 25.0 16.8 19.8 21.0 36.9 14.7 17.9 13.5 11.0 15.0 15.6 16.3 23.7 14.4 12.2 22.3 24.8 26.1 23.5 33.7 16.2 24.9 26.2 16.1 11.8 15.0 18.6 24.3 21.5 27.9 16.8 21.9 13.0 15.1 16.7 60.8 16.7 14.3 20.6 26.0 20.2 13.6 19.0 15.3 22.1 18.2 21.6 25.6 15.2 13.1 22.9 27.2 13.1 24.6 23.6 29.6 24.7 35.2 30.7 34.6 30.3 25.2 21.5 42.3 37.2 35.8 53.2 43.4 45.1 30.1 41.9 56.7 27.0 27.2 37.6 39.3 53.3 43.6 28.3 41.8 24.9 50.6 31.0 40.5 24.9 16.4 29.8 60.1 56.2 39.5 45.3 30.2 44.2 33.7 29.8 30.6 48.0 46.6 25.8 33.6 40.9 46.8 30.3 30.1 22.1 25.2 28.5 34.3 19.4 26.1 31.2 35.7 33.6 24.2 40.5 18.1 48.8 39.4 38.3 27.0 39.2 13.1 17.9 8.8 25.3 24.6 26.5 22.9 27.4 27.0 27.2 19.1 22.2 26.5 1.9 23.6 19.1 26.7 29.6 24.7 24.8 25.0 21.0 36.9 24.8 26.1 26.2 16.1 27.9 15.3 PSMD7 "MOV34, P40, Rpn8, S12" ENSG00000103035 "Proteasome 26S subunit, non-ATPase 7" P51665 16 74296775-74306288 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019379, HPA049824, HPA056069" Enhanced Enhanced Nucleoplasm 340000 Nucleoplasm "CAB019379: , HPA049824: AB_2680899, HPA056069: AB_2683025" "unprognostic (4.75e-3)" "unprognostic (1.30e-1)" "unprognostic (2.84e-2)" "unprognostic (6.95e-2)" "unprognostic (7.62e-2)" "prognostic unfavourable (6.64e-5)" "prognostic unfavourable (7.71e-6)" "unprognostic (1.97e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (9.34e-3)" "unprognostic (1.34e-2)" "unprognostic (2.52e-2)" "unprognostic (5.06e-3)" "unprognostic (7.04e-2)" "unprognostic (2.12e-1)" "unprognostic (1.86e-2)" 26.5 30.3 23.6 20.8 32.8 45.7 21.7 21.7 34.4 17.7 26.6 22.4 17.0 19.8 24.3 26.1 31.5 16.9 17.6 59.0 22.0 21.7 25.0 47.8 20.3 23.5 24.9 22.9 17.1 18.8 23.2 17.4 44.1 36.1 30.3 28.3 16.7 22.8 27.1 88.8 30.6 22.3 26.4 25.1 27.1 21.8 20.3 22.4 30.7 18.2 34.4 28.4 34.6 22.3 50.3 71.0 64.7 60.8 44.6 56.5 58.1 27.0 45.0 33.4 17.1 24.2 25.0 42.1 38.0 32.1 46.8 43.4 59.5 37.6 37.0 42.2 30.7 35.0 26.6 34.4 41.8 21.9 29.3 28.6 34.9 45.4 31.9 46.3 48.7 23.0 34.7 42.2 42.3 41.0 42.3 16.4 29.7 66.9 26.5 43.8 36.2 22.6 38.4 21.6 49.1 24.8 40.8 21.3 24.1 36.9 13.9 21.8 29.4 31.8 37.1 28.1 23.6 30.6 28.3 35.2 45.2 107.8 38.3 33.8 29.0 45.6 58.4 64.7 49.8 60.8 48.5 50.3 49.7 52.0 71.0 36.1 48.7 49.9 34.8 44.6 60.2 59.6 56.5 58.1 23.6 32.8 21.7 34.4 22.0 21.7 24.9 22.9 36.1 22.4 PSPH PSP ENSG00000146733 "Phosphoserine phosphatase" P78330 7 56011051-56051604 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020376, HPA029515" Approved Approved Cytosol Cytosol "HPA020376: AB_1855867, HPA029515: AB_10601492" "prognostic unfavourable (2.30e-4)" "unprognostic (7.80e-2)" "unprognostic (1.55e-1)" "unprognostic (2.03e-1)" "unprognostic (1.07e-1)" "unprognostic (7.66e-3)" "prognostic unfavourable (2.75e-5)" "unprognostic (1.74e-1)" "unprognostic (2.13e-1)" "unprognostic (4.45e-2)" "prognostic favourable (3.77e-4)" "unprognostic (3.78e-2)" "unprognostic (5.74e-2)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.90e-3)" "unprognostic (9.05e-3)" 7.5 13.4 14.1 5.9 16.6 5.1 11.0 10.1 14.6 5.4 8.0 13.2 11.4 6.9 7.0 9.0 11.0 26.3 10.6 12.8 13.2 12.5 14.7 9.8 5.4 7.4 14.8 10.0 13.9 15.9 7.8 17.1 6.4 11.1 10.6 6.9 6.9 6.8 11.5 6.8 6.4 6.2 8.5 15.2 5.7 8.5 9.1 13.3 10.2 12.2 6.9 8.5 7.1 16.0 7.8 11.9 6.8 8.5 5.3 6.2 5.8 46.3 14.2 8.7 32.5 7.3 9.8 6.0 11.7 6.9 6.6 11.7 12.7 8.1 22.9 7.9 10.8 9.7 19.2 9.9 6.8 17.4 10.8 6.4 3.8 21.4 15.7 6.4 9.8 12.3 18.8 10.4 12.0 6.4 15.3 14.8 9.8 6.2 9.8 15.3 13.9 19.9 12.8 5.2 13.1 6.2 2.4 15.9 18.4 8.5 5.2 23.4 15.7 13.5 5.4 5.7 9.0 17.6 10.7 10.2 17.8 26.0 8.2 14.1 17.9 2.2 7.7 6.8 4.2 5.3 3.0 7.2 4.0 5.1 11.9 7.8 6.2 5.5 3.6 5.3 8.5 11.3 5.1 5.8 14.1 16.6 10.1 14.6 13.2 12.5 14.8 10.0 11.1 13.3 PSTK "C10orf89, MGC35392" ENSG00000179988 "Phosphoseryl-tRNA kinase" Q8IV42 10 122954381-122997513 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037780, HPA037781" Approved Approved "Nucleoli,Nuclear bodies,Actin filaments" "Actin filaments" "Nucleoli, Nuclear bodies" "HPA037780: , HPA037781: AB_10670530" "unprognostic (8.95e-3)" "unprognostic (5.51e-3)" "unprognostic (1.37e-1)" "unprognostic (7.39e-4)" "unprognostic (5.21e-2)" "unprognostic (4.08e-3)" "unprognostic (1.60e-2)" "unprognostic (5.92e-4)" "unprognostic (3.55e-2)" "unprognostic (1.16e-1)" "unprognostic (6.22e-3)" "unprognostic (7.10e-3)" "unprognostic (2.39e-1)" "unprognostic (4.50e-2)" "unprognostic (4.92e-2)" "unprognostic (3.02e-2)" "unprognostic (5.55e-4)" 2.8 5.6 7.0 2.5 8.8 12.5 8.8 4.3 10.4 5.8 4.3 10.5 4.7 4.6 5.4 11.4 3.7 5.6 3.5 4.7 7.5 7.3 5.5 10.6 2.8 4.0 8.8 8.7 3.8 5.4 4.2 7.2 3.7 9.3 5.6 4.3 3.8 4.3 3.6 6.8 3.8 3.8 5.4 8.7 2.9 3.0 11.1 8.6 2.9 6.8 1.4 3.6 4.8 3.2 6.5 7.4 6.3 5.5 6.6 10.0 6.0 5.4 3.8 2.0 1.0 2.5 4.7 2.6 2.0 5.2 4.6 5.5 5.6 4.8 5.5 5.0 3.7 2.9 1.0 4.6 5.3 2.9 10.2 3.7 0.9 4.4 6.0 7.6 4.6 5.2 8.0 4.1 7.9 3.2 5.1 8.5 6.7 8.1 2.6 4.7 4.7 5.5 5.5 3.6 5.0 6.9 3.3 2.2 2.4 4.6 5.2 7.6 2.4 0.6 3.8 3.6 3.4 1.4 5.2 3.1 1.7 7.5 3.3 5.2 1.4 0.0 5.5 6.3 8.9 3.3 10.0 6.5 6.9 8.4 7.4 5.8 9.2 9.4 0.6 6.6 3.9 7.0 4.2 6.0 7.0 8.8 4.3 10.4 7.5 7.3 8.8 8.7 9.3 8.6 PTDSS1 "KIAA0024, PSS1, PSSA" ENSG00000156471 "Phosphatidylserine synthase 1" P48651 8 96261715-96336995 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016852 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" "Endoplasmic reticulum" Nucleoplasm "HPA016852: AB_1855878" "unprognostic (1.44e-1)" "unprognostic (1.71e-1)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (7.48e-2)" "unprognostic (5.68e-3)" "prognostic unfavourable (1.08e-5)" "prognostic unfavourable (9.83e-4)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.19e-1)" "unprognostic (2.29e-3)" "unprognostic (4.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.08e-2)" "unprognostic (3.55e-2)" 8.2 7.9 8.0 8.1 14.7 10.2 10.4 10.2 15.0 9.7 8.3 5.1 22.5 10.6 8.4 7.8 9.6 7.0 7.9 20.1 8.6 9.9 9.5 12.8 7.8 21.8 7.1 8.0 9.6 12.1 23.2 4.9 10.8 9.6 5.7 7.4 5.2 8.8 29.8 10.1 10.4 8.3 9.0 6.0 11.8 8.1 5.1 3.6 20.7 11.0 7.7 11.8 9.3 6.8 3.6 6.1 9.4 3.7 5.0 4.6 7.8 10.4 8.1 1.4 3.9 2.9 6.1 2.4 7.6 10.5 7.3 5.1 3.0 3.0 17.2 7.0 7.1 4.3 9.9 7.6 11.4 8.8 7.1 16.9 15.6 1.6 3.0 12.4 5.9 5.1 7.3 10.2 7.2 4.7 8.4 8.9 6.6 3.0 9.6 1.9 2.2 7.6 7.7 7.3 13.0 4.1 8.9 6.1 2.5 2.8 2.5 1.1 5.9 4.2 8.3 6.6 4.1 4.5 8.7 1.8 9.2 8.4 4.1 13.1 5.3 9.4 3.7 2.1 2.8 2.5 4.0 2.6 4.6 3.4 6.1 3.6 4.0 2.9 1.3 5.0 2.4 1.8 2.6 7.8 8.0 14.7 10.2 15.0 8.6 9.9 7.1 8.0 9.6 3.6 PTDSS2 PSS2 ENSG00000174915 "Phosphatidylserine synthase 2" Q9BVG9 11 448268-491399 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 35.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038928, HPA038929" Approved "HPA038928: AB_10672832, HPA038929: " "unprognostic (3.41e-1)" "unprognostic (2.52e-1)" "unprognostic (2.07e-1)" "unprognostic (5.75e-3)" "unprognostic (3.19e-2)" "unprognostic (1.44e-1)" "prognostic unfavourable (5.12e-9)" "unprognostic (6.18e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-2)" "unprognostic (1.41e-3)" "unprognostic (6.41e-2)" "unprognostic (1.11e-2)" "unprognostic (3.39e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" 14.6 15.5 14.8 8.0 15.3 6.2 14.9 20.0 19.9 12.2 10.1 19.3 13.6 5.2 11.9 12.0 9.3 14.2 10.8 15.9 15.4 13.1 19.8 11.2 10.4 7.8 15.6 12.0 17.6 17.6 35.2 10.4 14.9 13.7 11.9 7.1 13.5 12.2 14.6 18.6 8.3 7.2 13.1 17.3 9.1 11.7 32.0 15.1 10.6 16.5 8.3 6.6 12.7 10.2 0.1 1.2 0.0 1.3 0.8 1.8 0.0 8.3 7.7 6.9 10.3 6.2 10.1 9.0 7.3 8.6 9.1 8.3 2.0 5.7 4.5 6.2 8.9 13.7 8.4 11.3 4.5 7.5 35.4 5.6 5.5 4.3 11.9 7.5 4.9 11.5 8.6 3.2 5.7 7.1 16.3 1.4 7.0 0.8 7.2 6.9 10.2 18.8 7.7 7.9 2.1 6.5 1.4 10.8 5.9 10.1 6.5 7.8 2.3 4.2 9.0 4.4 2.9 2.2 4.6 5.8 2.4 1.9 7.6 3.5 3.1 0.0 0.5 0.0 1.1 1.3 0.3 0.0 0.1 0.2 0.5 0.1 0.7 1.8 0.0 0.8 0.2 1.2 0.3 0.0 14.8 15.3 20.0 19.0 15.4 13.1 15.6 12.0 13.7 15.1 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863113-87971930 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 29.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Secreted - unknown location" Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: " "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavourable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 42.4 24.1 17.7 20.9 17.7 13.5 32.8 39.9 19.7 43.1 26.7 9.9 19.0 15.1 29.8 22.8 26.8 30.3 21.0 19.1 16.0 17.4 19.6 32.4 27.2 30.4 15.7 19.5 29.1 21.3 16.4 23.6 36.4 14.2 35.3 17.7 21.6 16.8 20.8 16.8 20.4 25.4 26.0 11.7 40.9 17.8 18.7 12.5 49.7 25.2 13.3 18.6 29.6 30.9 4.3 5.1 29.6 11.0 4.3 4.7 2.0 10.4 4.9 5.7 5.1 13.1 9.0 5.1 5.6 12.5 6.6 9.3 5.0 12.9 12.3 3.8 9.2 6.3 7.5 6.4 10.5 6.2 2.1 4.1 12.8 6.1 14.0 13.8 7.1 6.1 17.9 8.3 10.8 9.3 3.1 33.6 6.0 8.0 7.7 25.1 2.1 0.0 12.0 3.0 9.1 10.3 6.0 2.0 9.2 7.5 3.5 9.4 9.9 20.0 8.1 21.9 5.1 8.5 4.5 11.1 14.3 14.1 6.8 13.1 1.3 8.3 7.9 12.2 3.6 11.0 3.9 4.3 4.0 3.5 5.1 3.7 4.7 4.5 29.6 4.3 7.2 4.2 3.5 2.0 17.7 17.7 39.9 19.7 16.0 17.4 15.7 19.5 14.2 12.5 PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 286.6;retina: 331.2" "Group enriched" "Detected in some" 6 "HHSteC: 103.8;HSkMC: 50.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 27 "plasmacytoid DC: 140.9" "Lineage enriched" "Detected in many" 27 "dendritic cells: 140.9" "HPA004938, CAB009916" Approved "Secreted to blood" 4300000000 "CAB009916: AB_2174617, HPA004938: AB_1855745" "unprognostic (2.79e-2)" "unprognostic (3.96e-3)" "unprognostic (9.70e-2)" "unprognostic (5.71e-3)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (1.19e-7)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-2)" 34.1 27.9 138.1 37.5 159.8 2.5 11.3 61.5 154.6 260.4 10.5 192.5 23.0 6.4 22.5 130.0 26.0 72.4 65.8 286.6 121.0 85.2 22.3 6.0 39.7 114.8 170.8 130.6 7.0 20.0 1.8 20.6 38.5 118.8 78.5 4.2 331.2 18.8 149.8 17.0 19.7 11.2 18.6 188.0 50.1 13.5 218.5 103.2 3.3 3.4 4.3 51.1 49.5 75.8 0.0 140.9 0.2 0.1 0.3 5.2 1.0 0.0 0.0 0.0 0.0 1.0 3.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 4.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 103.8 0.0 0.2 50.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.1 13.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 5.2 0.1 0.3 0.0 0.4 0.6 0.1 0.0 0.1 1.1 0.2 0.3 0.0 140.9 0.1 1.0 138.1 159.8 61.5 154.6 121.0 85.2 170.8 130.6 118.8 103.2 PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753047 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "ductus deferens: 59.8;placenta: 51.7;seminal vesicle: 182.9" "Cell line enhanced" "Detected in many" "ASC diff: 31.0;BEWO: 32.9;HaCaT: 43.0;SK-BR-3: 31.6;U-2197: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "basophil: 16.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 16.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045064 Enhanced Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA045064: AB_10795889" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "prognostic unfavourable (2.32e-4)" "unprognostic (2.54e-2)" "unprognostic (1.94e-3)" "unprognostic (1.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.24e-3)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "prognostic unfavourable (7.97e-5)" "unprognostic (2.22e-1)" "unprognostic (4.66e-2)" "unprognostic (9.78e-3)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.20e-2)" 17.0 0.6 1.1 6.2 1.7 3.0 16.7 1.1 1.8 11.9 4.2 0.8 59.8 1.2 2.0 9.1 8.7 2.7 4.1 4.2 2.1 3.5 3.9 0.4 3.5 3.1 1.3 0.7 2.7 0.6 6.3 0.7 51.7 2.1 11.2 2.0 2.9 16.3 182.9 2.5 19.8 3.7 4.8 1.4 1.3 3.4 9.9 0.6 2.3 1.7 6.6 14.1 14.5 15.0 0.0 0.1 16.8 3.2 0.0 0.0 0.1 0.2 19.3 0.0 9.2 31.0 10.7 32.9 1.4 12.7 0.2 0.3 0.9 14.1 0.0 0.5 3.5 43.0 0.1 1.4 0.1 0.0 0.1 0.0 13.7 0.0 0.7 0.0 0.0 6.3 10.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 1.7 0.0 0.0 0.0 1.0 20.6 0.1 0.7 17.2 31.6 0.1 16.5 0.0 0.1 0.0 0.0 81.7 0.0 0.0 0.0 0.0 16.2 0.0 0.1 16.8 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 3.2 0.0 0.0 0.1 1.1 1.7 1.1 1.8 2.1 3.5 1.3 0.7 2.1 0.6 PTGES2 "C9orf15, FLJ14038" ENSG00000148334 "Prostaglandin E synthase 2" Q9H7Z7 9 128120693-128128462 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020631, HPA020733" Approved Approved Mitochondria Mitochondria "HPA020631: AB_1855887, HPA020733: " "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (1.68e-2)" "unprognostic (5.13e-3)" "unprognostic (2.56e-1)" "unprognostic (1.57e-1)" "unprognostic (7.10e-2)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "prognostic favourable (5.83e-7)" "unprognostic (2.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" 9.3 17.0 16.5 9.2 17.8 4.4 7.4 15.3 24.1 7.1 14.8 9.9 7.6 17.7 8.1 9.0 12.6 8.4 10.0 36.4 17.4 14.0 13.2 13.0 5.8 10.2 14.2 11.6 9.2 18.3 11.7 14.3 10.7 10.5 8.0 7.0 13.2 16.2 12.0 73.5 9.3 13.2 5.9 7.0 9.5 14.3 5.8 9.8 9.3 10.5 16.2 13.3 8.5 7.3 5.2 8.2 1.2 6.3 3.7 6.5 2.9 12.6 35.4 3.9 14.7 3.6 3.7 12.1 9.7 5.4 12.3 6.6 26.4 19.8 11.2 15.5 3.9 32.9 5.7 12.0 1.7 8.0 15.4 5.7 26.8 24.6 11.0 11.6 11.5 5.0 8.7 9.9 6.8 8.4 12.6 7.0 4.0 39.1 13.8 22.1 12.6 28.7 10.5 7.9 28.5 8.4 9.5 19.8 11.8 14.0 22.4 9.4 20.0 6.2 11.0 12.6 15.7 17.0 17.6 16.1 7.8 10.9 9.6 9.0 11.7 1.2 6.0 1.0 5.6 6.3 6.5 5.2 3.7 5.9 6.7 4.5 4.3 5.1 1.1 3.7 2.8 8.2 4.2 2.9 16.5 17.8 15.3 24.1 17.4 14.0 14.2 11.6 10.5 9.8 PTGES3 "cPGES, p23, TEBP" ENSG00000110958 "Prostaglandin E synthase 3" Q15185 12 56663341-56688408 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 358.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034319, HPA038672, HPA038673" Enhanced Approved Nucleoplasm,Cytosol 580000 Cytosol Nucleoplasm "CAB034319: AB_2175206, HPA038672: AB_10697395, HPA038673: AB_10670786" "prognostic unfavourable (2.15e-5)" "unprognostic (2.60e-1)" "unprognostic (8.67e-3)" "unprognostic (7.07e-2)" "unprognostic (2.24e-1)" "unprognostic (2.96e-3)" "prognostic unfavourable (4.44e-6)" "unprognostic (4.33e-3)" "unprognostic (3.64e-2)" "prognostic favourable (4.36e-4)" "unprognostic (2.73e-2)" "unprognostic (2.31e-2)" "unprognostic (3.05e-3)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" "unprognostic (2.07e-1)" 44.7 41.4 56.0 41.2 55.7 39.6 175.0 44.2 51.7 49.0 51.9 38.1 49.5 46.4 57.7 52.0 52.6 69.8 36.0 46.0 54.6 57.2 52.1 67.1 46.4 62.0 67.0 41.4 82.3 55.1 43.2 49.2 50.3 57.0 60.7 55.3 24.0 36.6 49.4 64.2 37.0 46.7 64.7 72.5 42.7 36.6 39.7 65.1 53.5 72.5 36.7 55.1 72.7 358.9 40.6 36.9 27.3 74.8 29.2 42.5 60.5 79.9 69.8 56.6 33.7 41.7 37.9 86.3 52.4 40.1 67.5 50.5 59.1 84.4 88.7 79.7 44.7 51.6 106.1 68.5 85.6 65.1 70.6 69.2 44.1 68.2 30.6 82.2 50.3 27.4 50.1 51.0 61.9 69.4 111.0 85.0 65.9 49.9 81.6 78.1 96.7 81.5 71.4 53.4 119.0 59.4 62.6 73.4 42.9 53.5 77.2 45.4 88.9 69.1 41.6 40.6 47.2 48.7 72.4 35.8 98.6 71.3 44.2 67.9 73.0 27.3 37.5 23.2 32.0 59.0 42.0 40.6 42.5 38.1 36.9 28.5 42.3 36.4 14.8 29.2 74.8 31.3 42.5 60.5 56.0 55.7 44.2 51.7 54.6 57.2 67.0 41.4 57.0 65.1 PTGIS "CYP8A1, PGIS" ENSG00000124212 "Prostaglandin I2 synthase" Q16647 20 49503874-49568146 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 88.2" "Group enriched" "Detected in some" 4 "ASC diff: 17.4;ASC TERT1: 17.5;U-2197: 53.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009517, HPA014193, HPA052244" Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB009517: AB_2173209, HPA014193: AB_1855746, HPA052244: " "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (5.09e-3)" "unprognostic (1.38e-2)" "unprognostic (1.80e-2)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (2.45e-2)" "unprognostic (5.22e-2)" "prognostic unfavourable (4.74e-8)" "unprognostic (2.29e-2)" "unprognostic (7.61e-2)" "unprognostic (4.89e-3)" "prognostic unfavourable (9.99e-5)" 18.2 2.5 0.6 8.0 1.3 0.1 28.3 0.2 1.6 23.3 14.6 0.5 6.5 1.7 36.5 21.7 13.2 32.0 36.3 23.8 0.3 0.5 3.0 3.8 7.5 1.6 0.5 0.9 51.2 1.3 0.2 0.5 1.0 1.0 27.2 3.7 3.2 3.7 4.6 7.0 3.2 4.4 88.2 1.4 0.3 8.7 16.2 0.3 0.0 6.7 5.6 1.7 64.2 36.1 1.0 0.8 2.7 0.6 0.8 0.5 0.1 0.0 0.0 0.7 0.0 17.4 17.5 0.2 0.3 2.1 0.0 0.0 0.0 0.0 0.0 6.9 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 53.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.6 0.4 0.4 0.4 0.3 0.4 0.3 0.3 0.1 1.0 0.4 0.5 2.7 0.8 0.3 0.8 0.2 0.1 0.6 1.3 0.2 1.6 0.3 0.5 0.5 0.9 1.0 0.3 PTGR1 "LTB4DH, ZADH3" ENSG00000106853 "Prostaglandin reductase 1" Q14914 9 111549722-111599855 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 117.6;liver: 113.8" "Cell line enhanced" "Detected in many" "Hep G2: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "plasmacytoid DC: 8.9" "Lineage enriched" "Detected in single" 9 "dendritic cells: 8.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036724 Enhanced 940000 "HPA036724: AB_10670239" "unprognostic (1.54e-1)" "unprognostic (2.23e-1)" "unprognostic (1.10e-2)" "unprognostic (3.02e-3)" "unprognostic (8.46e-2)" "unprognostic (1.02e-3)" "unprognostic (1.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (3.48e-1)" "prognostic favourable (5.53e-4)" "unprognostic (2.25e-1)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (5.22e-2)" 9.9 23.7 6.7 3.4 8.1 0.4 8.0 9.7 10.0 8.0 116.3 2.2 3.0 45.2 8.0 7.8 27.4 14.3 15.2 7.7 7.0 4.2 47.3 113.8 5.2 2.6 3.3 6.6 5.9 4.3 6.2 9.0 3.2 6.4 12.3 6.7 6.8 11.4 6.4 3.3 6.7 117.6 8.7 2.5 2.2 21.2 3.3 3.4 1.1 9.0 36.4 12.5 21.9 23.6 0.3 8.9 0.2 0.9 0.0 0.2 0.5 10.1 43.1 12.6 0.1 46.2 46.7 9.8 16.5 25.1 15.8 16.5 11.7 13.8 0.0 4.7 15.7 12.5 10.2 17.4 19.6 0.0 3.0 2.5 26.8 56.7 10.6 1.4 5.3 33.2 26.3 21.6 11.1 39.8 1.7 0.0 30.5 3.1 0.0 0.3 5.2 10.6 0.0 3.6 0.2 18.4 33.2 14.2 0.6 20.3 6.1 6.0 19.0 6.9 32.1 3.1 6.5 35.2 2.9 0.0 0.0 0.0 15.0 0.0 3.9 0.0 0.9 0.0 0.0 0.1 0.2 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.0 0.0 8.9 0.0 0.5 6.7 8.1 9.7 10.0 7.0 4.2 3.3 6.6 6.4 3.4 PTGR2 "FLJ39091, ZADH1" ENSG00000140043 "Prostaglandin reductase 2" Q8N8N7 14 73851844-73886827 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 28.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA001125 Approved Approved Vesicles 1000000 Vesicles "HPA001125: " "unprognostic (3.82e-2)" "unprognostic (2.79e-2)" "unprognostic (6.05e-2)" "unprognostic (3.26e-1)" "unprognostic (2.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (8.10e-3)" "unprognostic (6.99e-3)" "unprognostic (5.96e-1)" "prognostic favourable (4.55e-12)" "unprognostic (4.42e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (7.24e-2)" 7.4 14.4 16.0 3.4 17.2 1.6 10.9 8.0 13.3 6.2 8.3 15.3 11.9 13.7 5.8 20.3 6.2 13.9 6.4 29.0 15.0 12.2 22.1 20.9 6.6 3.7 15.2 12.6 9.1 6.4 13.8 12.8 3.2 20.4 10.9 6.9 10.1 7.7 8.9 32.4 8.1 9.9 4.9 16.0 4.1 7.0 11.5 17.2 2.0 14.6 9.1 3.4 5.5 7.0 2.2 3.2 8.4 2.4 2.3 4.0 2.3 5.7 7.9 6.5 3.2 5.3 11.5 5.1 2.0 2.8 2.5 3.8 4.5 14.2 0.6 4.7 2.0 5.9 5.8 4.3 4.6 4.4 2.7 4.0 3.7 1.9 2.6 1.5 1.5 5.3 10.3 3.7 3.1 1.2 5.3 1.2 5.5 8.3 4.0 3.9 7.2 7.9 4.9 2.5 1.0 13.4 5.7 8.7 7.6 5.2 5.5 6.4 28.4 2.5 1.8 3.7 6.9 2.6 4.3 7.0 3.0 1.8 5.7 3.6 4.9 8.4 2.4 1.8 1.6 0.9 1.2 2.1 2.3 1.2 2.6 2.2 4.0 3.2 2.0 2.3 2.2 3.2 2.1 2.3 16.0 17.2 8.0 13.3 15.0 12.2 15.2 12.6 20.4 17.2 PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 211.4;urinary bladder: 163.9" "Cell line enhanced" "Detected in some" "ASC diff: 28.1;ASC TERT1: 22.3;BJ: 27.3;BJ hTERT+: 37.3;HEL: 17.1;HMC-1: 72.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 53.4" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 13.0;granulocytes: 14.4;monocytes: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002834, CAB020315" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" 25000000 "Golgi apparatus" Vesicles "CAB020315: , HPA002834: AB_1079711" "unprognostic (4.20e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (5.88e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-3)" "unprognostic (3.32e-1)" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "prognostic unfavourable (8.68e-4)" "unprognostic (4.03e-2)" "unprognostic (1.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavourable (9.35e-4)" 4.5 1.1 1.8 9.1 3.1 2.6 2.5 0.5 2.7 2.6 35.3 4.6 3.0 3.9 2.5 1.6 25.7 16.7 9.4 4.9 1.9 1.6 3.9 1.8 4.0 1.4 3.5 0.7 3.6 1.0 0.7 2.4 0.8 2.5 60.9 9.3 1.5 1.9 2.3 0.7 55.9 6.5 211.4 4.9 3.6 7.8 1.0 3.1 0.4 1.5 5.3 4.2 163.9 19.5 2.5 13.0 14.4 8.5 1.9 0.1 13.7 0.0 0.1 0.1 0.0 28.1 22.3 0.0 27.3 37.3 0.2 0.2 0.0 0.0 0.9 1.3 4.6 1.7 0.0 2.5 0.2 0.0 0.0 17.1 0.1 0.0 8.1 1.1 72.7 11.4 0.2 1.4 0.0 10.1 0.0 0.0 0.5 0.0 0.0 1.5 0.3 0.1 0.0 0.3 2.0 3.5 0.0 0.1 0.1 0.1 2.3 0.0 0.0 1.9 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 7.4 0.0 12.0 7.6 14.4 0.0 8.5 0.0 1.7 0.0 0.0 13.0 2.5 0.0 0.0 3.5 1.9 6.1 0.9 0.1 13.7 1.8 3.1 0.5 2.7 1.9 1.6 3.5 0.7 2.5 3.1 PTGS2 COX2 ENSG00000073756 "Prostaglandin-endoperoxide synthase 2" P35354 1 186671791-186680427 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "ductus deferens: 324.6;seminal vesicle: 377.9" "Cell line enriched" "Detected in some" 4 "BJ hTERT+: 93.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 16 "neutrophil: 12.8" "Lineage enriched" "Detected in single" 16 "granulocytes: 12.8" "Region enhanced" "Detected in many" "hippocampal formation: 16.5" "Low region specificity" "Detected in many" "CAB000113, HPA001335" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "CAB000113: , HPA001335: AB_1079712" "unprognostic (1.36e-3)" "unprognostic (9.97e-3)" "unprognostic (3.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (9.50e-2)" "unprognostic (9.03e-3)" "unprognostic (2.81e-1)" "unprognostic (3.24e-2)" "unprognostic (3.07e-2)" "prognostic unfavourable (9.79e-4)" "unprognostic (8.04e-3)" "unprognostic (4.38e-2)" "unprognostic (8.89e-2)" "unprognostic (3.74e-2)" 5.7 2.1 1.2 3.7 1.1 32.6 1.5 0.8 1.9 21.1 11.4 1.1 324.6 0.4 2.3 1.8 1.7 4.0 9.5 9.1 1.1 1.0 3.3 2.7 22.1 2.3 1.3 0.8 1.6 0.4 3.1 2.2 2.5 1.9 9.2 2.7 3.9 0.9 377.9 1.0 1.1 2.4 7.7 4.7 0.9 11.4 1.0 0.9 0.6 1.5 3.4 1.3 17.3 1.9 0.0 0.5 12.8 0.8 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.5 0.5 0.0 21.3 93.1 0.1 0.8 3.3 3.9 0.0 0.0 0.1 2.8 0.0 1.7 0.3 0.0 0.0 0.1 0.5 0.0 3.1 0.0 0.1 0.2 0.6 2.6 6.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 0.0 0.2 0.0 0.2 0.0 0.1 0.3 4.5 0.1 3.1 0.1 0.0 0.0 0.0 6.5 0.1 0.5 0.0 0.4 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 12.8 0.0 0.4 0.0 0.0 0.0 1.2 1.1 0.8 1.9 1.1 1.0 1.3 0.8 1.9 0.9 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" 32000 "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavourable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavourable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 22.6 20.4 36.0 14.4 42.3 3.1 19.3 20.5 40.8 24.9 17.9 55.7 23.5 14.5 20.2 29.9 14.6 18.7 18.4 20.0 43.5 23.9 22.3 17.0 21.5 13.0 41.4 31.4 19.4 18.2 33.1 13.0 42.1 30.0 19.2 20.7 11.0 21.9 25.5 17.9 13.5 16.3 21.9 38.0 12.2 17.5 21.2 46.1 2.8 22.5 10.2 14.0 22.2 17.8 8.6 7.2 1.8 3.9 5.2 5.7 4.1 14.6 23.4 32.5 11.7 13.7 14.7 21.0 14.5 20.2 13.6 13.4 10.2 12.2 8.9 33.0 18.6 17.4 19.1 33.3 20.6 0.1 8.9 19.7 12.9 14.0 18.7 0.0 9.4 10.0 16.4 17.0 24.0 40.1 19.8 0.2 18.2 25.5 0.2 0.2 12.6 26.2 13.1 17.8 0.4 28.7 33.5 12.9 16.1 22.7 7.3 14.7 17.2 0.3 24.2 13.4 25.3 15.8 16.3 0.0 0.1 0.9 17.4 0.1 18.1 1.8 3.9 0.0 0.3 1.6 0.0 6.8 0.8 0.1 5.3 8.6 5.7 2.0 1.7 5.2 0.9 7.2 0.2 4.1 36.0 42.3 20.5 40.8 43.5 23.9 41.4 31.4 30.0 46.1 PTK2B "CADTK, CAKB, FAK2, PTK, PYK2, RAFTK" ENSG00000120899 "Protein tyrosine kinase 2 beta" Q14289 8 27311482-27459391 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 46.7;brain: 65.2" "Cell line enhanced" "Detected in many" "Daudi: 37.0;REH: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 202.9;basal ganglia: 236.9;cerebral cortex: 189.7;hippocampal formation: 443.3;olfactory region: 185.5" "Low region specificity" "Detected in many" "CAB003850, HPA026091, HPA026276" Approved Supported "Plasma membrane,Cytosol" 84000 "Plasma membrane, Cytosol" "CAB003850: AB_562205, HPA026091: AB_10599739, HPA026276: AB_10601234" "unprognostic (2.36e-2)" "prognostic favourable (3.32e-4)" "unprognostic (1.06e-1)" "unprognostic (7.36e-3)" "unprognostic (3.72e-2)" "unprognostic (3.11e-2)" "unprognostic (2.70e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-2)" "unprognostic (3.32e-1)" "unprognostic (2.40e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "prognostic favourable (5.11e-4)" "unprognostic (3.33e-3)" 7.2 4.7 20.4 24.3 30.0 46.7 4.9 65.2 48.3 5.4 14.5 7.8 5.0 16.6 4.3 4.7 7.9 6.8 6.4 4.7 30.5 7.0 6.8 5.0 11.5 35.6 4.3 25.4 2.4 5.4 5.2 5.3 4.1 3.9 10.1 11.9 8.3 12.6 6.7 2.2 15.1 18.4 5.5 4.8 32.0 10.8 4.3 3.7 37.8 5.6 2.9 35.4 13.0 6.0 26.9 18.7 24.0 25.8 14.7 19.0 21.5 10.9 3.0 0.8 0.9 23.5 1.7 6.4 0.8 0.5 0.6 0.8 2.9 6.3 37.0 1.2 1.7 10.1 0.3 9.2 0.3 2.5 0.2 7.6 2.9 0.5 4.8 8.2 13.8 12.7 13.8 0.8 5.3 0.3 8.9 25.7 0.6 1.1 14.0 16.5 0.6 0.8 41.0 0.2 25.3 2.6 8.6 5.8 1.0 3.9 2.7 1.4 3.3 21.2 5.2 0.4 0.8 0.7 0.3 20.7 8.9 20.0 1.6 17.8 0.7 22.3 23.7 18.0 19.0 22.4 12.5 25.5 9.6 13.3 18.7 26.9 12.1 14.2 24.0 14.7 25.8 6.2 9.5 21.5 20.4 30.0 65.2 48.3 30.5 7.0 4.3 25.4 3.9 3.7 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537370 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.0;intestine: 24.2;skin 1: 24.2" "Cell line enhanced" "Detected in some" "A-431: 11.3;CAPAN-2: 21.8;HaCaT: 17.7;hTCEpi: 24.0;RT4: 13.8;T-47d: 13.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavourable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavourable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.7 0.0 0.4 5.3 0.4 0.0 1.7 0.4 0.4 7.6 18.1 0.5 0.8 13.6 0.6 0.5 44.0 0.0 11.7 0.4 0.4 0.0 0.8 1.7 1.1 0.4 0.4 0.4 0.4 1.4 0.0 0.4 0.6 0.4 2.2 7.4 0.4 7.6 0.4 0.4 24.2 24.2 0.9 0.4 0.4 12.5 0.4 0.4 0.4 0.4 18.9 17.2 6.5 15.0 1.3 4.5 1.2 2.4 0.3 1.9 0.9 11.3 1.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 21.8 0.0 3.9 0.0 17.7 0.0 0.0 0.0 2.8 0.2 0.0 4.5 0.0 0.0 0.0 3.6 0.0 24.0 0.0 0.1 0.0 0.1 1.3 0.1 6.3 0.0 0.1 0.1 8.2 0.0 0.6 0.2 0.0 13.8 0.2 1.2 1.3 4.3 0.0 13.3 0.8 0.1 0.2 0.2 0.4 0.1 0.2 0.1 0.0 0.2 0.2 0.6 1.2 2.4 0.4 0.5 1.7 1.9 1.2 0.4 0.1 4.5 1.3 0.4 0.6 1.2 0.3 1.3 0.3 0.5 0.9 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 PTK7 CCK4 ENSG00000112655 "Protein tyrosine kinase 7 (inactive)" Q13308 6 43076268-43161719 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 9 "plasmacytoid DC: 13.8" "Lineage enriched" "Detected in many" 9 "dendritic cells: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003222 Approved "Secreted to blood" 10000000 "HPA003222: AB_1079713" "unprognostic (1.80e-1)" "unprognostic (7.49e-3)" "unprognostic (6.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.65e-1)" "unprognostic (1.15e-2)" "unprognostic (5.85e-3)" "unprognostic (9.81e-3)" "unprognostic (1.47e-3)" "unprognostic (7.15e-2)" "unprognostic (5.11e-3)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.73e-1)" "unprognostic (3.61e-1)" "unprognostic (9.12e-2)" "unprognostic (5.70e-3)" 5.4 1.8 1.4 3.5 3.4 0.8 12.2 3.5 4.9 30.9 4.8 3.4 8.9 2.1 37.7 36.9 11.7 14.3 14.5 3.5 2.2 3.9 10.1 0.8 18.7 4.3 1.3 2.7 42.6 16.3 9.0 9.0 20.9 4.2 18.2 3.3 13.9 15.0 10.9 0.4 13.6 3.4 16.4 3.2 12.4 4.6 14.9 1.4 28.7 19.3 8.1 6.2 9.5 17.6 0.0 13.8 0.3 0.0 0.7 1.5 0.8 2.1 0.6 21.1 35.1 22.7 23.3 30.0 22.6 36.5 19.8 25.4 19.0 7.6 0.0 17.9 26.3 24.5 9.4 21.5 12.6 0.1 11.7 2.0 4.3 25.5 34.5 0.0 0.1 33.3 19.5 26.1 8.3 2.5 1.3 0.0 9.0 1.6 7.6 3.0 9.8 1.7 7.7 30.0 0.0 15.3 10.5 12.1 23.0 3.6 0.3 11.7 12.9 4.6 1.6 21.2 13.4 0.1 12.2 0.1 0.2 0.7 4.9 0.0 3.5 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.1 1.5 0.2 0.7 0.0 13.8 0.0 0.8 1.4 3.4 3.5 4.9 2.2 3.9 1.3 2.7 4.2 1.4 PTP4A1 "PRL-1, PRL1, PTPCAAX1" ENSG00000112245 "Protein tyrosine phosphatase type IVA, member 1" Q93096 6 63521748-63583587 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 135.1;skeletal muscle: 111.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003281 Approved "HPA003281: AB_1855903" "unprognostic (8.63e-2)" "prognostic unfavourable (5.53e-4)" "unprognostic (9.05e-2)" "unprognostic (7.96e-2)" "unprognostic (2.79e-2)" "unprognostic (2.71e-2)" "unprognostic (6.12e-2)" "unprognostic (1.96e-1)" "unprognostic (5.28e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.23e-2)" "unprognostic (1.07e-2)" "unprognostic (6.64e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (1.11e-2)" 13.9 42.3 11.3 10.5 14.0 54.3 10.8 7.1 17.0 17.5 30.2 18.9 8.0 17.9 13.1 13.5 16.1 12.3 16.7 10.0 12.0 14.8 14.2 135.1 25.0 9.0 16.1 13.8 24.1 87.4 5.0 12.8 19.8 16.3 17.7 31.2 13.6 20.1 10.0 111.2 17.2 18.3 35.7 24.2 7.1 15.5 19.8 13.3 6.4 11.4 19.9 9.3 31.0 12.6 14.6 18.2 46.9 20.6 15.8 20.1 14.4 18.9 23.6 29.7 28.7 20.3 18.9 59.5 33.4 22.3 12.2 17.0 19.8 11.2 16.2 14.5 19.7 9.4 20.2 42.0 19.6 17.4 13.6 10.1 65.9 89.9 40.2 31.0 16.5 22.9 81.5 26.3 70.5 18.8 23.1 31.5 33.8 25.7 14.8 13.9 12.3 12.8 19.9 12.3 12.8 27.2 22.5 11.2 20.6 73.0 16.0 32.9 15.4 27.6 18.7 30.7 33.7 24.2 32.9 26.3 22.5 29.9 16.4 16.6 36.0 34.6 19.8 15.2 13.7 20.6 20.1 14.6 15.0 14.6 18.2 12.4 14.8 14.2 46.9 15.8 14.2 9.1 18.1 14.4 11.3 14.0 7.1 17.0 12.0 14.8 16.1 13.8 16.3 13.3 PTP4A2 "HU-PP-1, OV-1, PRL-2, PRL2, ptp-IV1a, PTP4A, PTPCAAX2" ENSG00000184007 "Protein tyrosine phosphatase type IVA, member 2" Q12974 1 31906421-31944856 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003281, CAB011204" Uncertain 440000 "CAB011204: AB_532271, HPA003281: AB_1855903" "unprognostic (2.67e-2)" "unprognostic (6.36e-2)" "unprognostic (3.15e-3)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (6.20e-2)" "prognostic unfavourable (2.62e-5)" "unprognostic (6.90e-2)" "unprognostic (4.63e-2)" "unprognostic (5.12e-2)" "unprognostic (1.99e-2)" "unprognostic (1.03e-1)" "prognostic unfavourable (5.10e-11)" "unprognostic (1.16e-2)" "unprognostic (3.81e-1)" "unprognostic (2.89e-1)" "prognostic favourable (2.72e-5)" 51.6 22.4 41.1 39.6 57.3 74.6 48.8 12.0 34.6 26.3 37.1 68.9 24.9 31.9 23.4 20.8 25.3 23.9 31.6 64.8 50.6 31.4 26.7 36.3 34.6 44.0 56.3 29.5 34.6 28.5 17.1 19.2 25.8 40.9 28.6 36.9 21.1 28.0 27.5 82.8 16.5 29.1 32.7 58.5 40.9 31.3 44.6 48.7 110.5 48.0 20.0 47.2 49.0 40.3 14.7 14.8 50.0 44.6 18.2 29.0 18.2 41.5 24.2 23.8 44.3 47.7 51.1 16.2 40.8 57.0 33.5 34.9 21.2 60.3 73.9 32.2 55.4 16.9 24.2 23.7 62.3 66.4 13.8 51.3 43.0 22.1 51.2 41.6 52.0 46.9 19.8 47.3 46.7 34.0 65.9 30.3 43.0 20.2 133.2 20.4 31.8 35.4 23.2 39.9 30.7 22.4 76.9 23.3 16.8 43.5 28.4 46.2 80.9 23.1 35.1 39.5 33.4 58.9 45.0 31.6 49.2 37.7 38.3 34.2 38.3 50.0 17.2 27.4 25.4 32.6 20.3 14.7 22.6 29.0 14.8 11.3 14.5 24.9 18.0 18.2 44.6 10.7 17.8 18.2 41.1 57.3 12.0 34.6 50.6 31.4 56.3 29.5 40.9 48.7 PTP4A3 "PRL-3, PRL-R, PRL3" ENSG00000184489 "Protein tyrosine phosphatase type IVA, member 3" O75365 8 141391993-141432454 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 166.4" "Cell line enhanced" "Detected in some" "HDLM-2: 68.7;Karpas-707: 20.9;RPMI-8226: 21.5;U-266/84: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 30.3;non-classical monocyte: 27.8" "Group enriched" "Detected in many" 7 "granulocytes: 30.3;monocytes: 27.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003281 Uncertain "HPA003281: AB_1855903" "unprognostic (1.09e-1)" "unprognostic (3.70e-1)" "unprognostic (2.55e-2)" "unprognostic (1.10e-3)" "unprognostic (2.08e-1)" "unprognostic (6.18e-2)" "unprognostic (3.61e-2)" "unprognostic (2.27e-2)" "unprognostic (1.08e-1)" "unprognostic (2.50e-1)" "unprognostic (5.73e-3)" "unprognostic (2.33e-2)" "prognostic unfavourable (1.81e-5)" "unprognostic (2.25e-1)" "unprognostic (1.12e-2)" "unprognostic (2.28e-2)" "unprognostic (1.77e-1)" 5.9 2.4 2.8 3.9 6.5 1.7 4.1 3.9 10.9 5.5 6.2 2.6 2.5 3.4 7.6 5.4 5.5 6.1 3.0 48.0 2.7 3.0 5.1 1.7 5.5 7.9 2.8 5.0 4.8 13.6 2.4 22.0 4.1 4.6 7.2 2.0 15.7 8.2 3.8 166.4 3.4 3.3 7.6 1.5 5.6 9.9 3.5 0.6 1.7 3.3 15.9 5.1 5.5 3.3 2.8 4.3 30.3 27.8 0.8 3.5 2.5 0.1 0.4 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 2.0 0.0 6.4 0.1 0.0 0.1 0.0 0.0 68.7 0.5 4.9 0.0 1.0 0.5 0.0 0.2 0.0 0.2 0.0 0.0 0.1 2.7 20.9 0.0 5.2 0.5 0.1 1.3 0.3 11.8 0.0 21.5 0.0 0.1 8.8 2.1 0.4 0.0 1.8 1.0 0.3 0.1 0.0 1.2 0.0 0.0 6.5 22.8 0.2 0.0 2.0 0.2 0.4 1.6 6.6 1.6 14.8 1.1 2.8 3.5 1.6 1.2 0.8 3.4 1.9 30.3 0.8 27.8 4.3 2.5 2.5 2.8 6.5 3.9 10.9 2.7 3.0 2.8 5.0 4.6 0.6 PTPA "PPP2R4, PR53" ENSG00000119383 "Protein phosphatase 2 phosphatase activator" Q15257 9 129110950-129148946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005695, CAB022068, CAB035999" Approved Enhanced Nucleoplasm,Cytosol 4800000 Nucleoplasm Cytosol "CAB022068: , CAB035999: , HPA005695: AB_1855658" "unprognostic (4.97e-2)" "unprognostic (1.70e-2)" "unprognostic (1.13e-2)" "prognostic favourable (6.50e-5)" "unprognostic (1.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.65e-2)" "unprognostic (6.44e-3)" "unprognostic (2.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.92e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" 16.5 35.1 41.6 19.8 41.2 18.1 23.9 32.0 74.2 27.5 27.4 27.2 30.1 18.3 26.7 26.0 31.8 30.1 28.7 42.1 38.0 32.4 32.6 41.0 22.1 19.8 30.8 35.5 23.2 22.4 55.0 22.5 21.4 37.0 33.4 21.7 20.8 36.0 41.5 110.7 27.2 18.8 35.3 21.9 24.4 23.8 62.4 17.6 23.7 27.2 37.0 21.3 22.1 23.9 12.6 19.2 7.8 15.5 17.7 18.4 14.9 24.8 44.1 27.2 50.4 18.4 22.6 27.2 26.0 29.5 35.8 25.0 23.6 30.7 25.9 19.7 44.1 40.5 28.4 32.1 30.8 46.0 15.5 16.0 46.7 22.4 54.8 27.6 34.8 27.0 31.7 26.1 24.9 36.4 23.7 28.8 30.0 64.5 25.1 17.1 42.7 43.9 25.1 25.1 47.6 37.5 31.2 29.5 20.9 52.7 54.4 32.5 57.7 12.0 26.7 29.7 26.9 30.6 36.7 26.3 67.3 23.4 36.6 18.0 40.9 5.8 15.5 7.8 18.4 15.5 17.6 9.6 14.0 16.4 19.2 12.6 13.1 13.1 5.4 17.7 14.4 13.8 14.0 14.9 41.6 41.2 32.0 74.2 38.0 32.4 30.8 35.5 37.0 17.6 PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase, mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040348, HPA043932" Approved Supported Mitochondria Mitochondria "HPA040348: , HPA043932: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavourable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 24.0 24.5 22.3 13.1 23.2 19.8 23.3 16.5 25.2 15.7 14.8 18.5 17.5 14.6 14.7 21.4 14.3 16.9 17.9 17.1 18.5 21.9 20.1 21.8 25.1 16.7 23.1 16.2 15.7 39.3 18.3 18.7 21.8 14.4 15.8 11.5 20.1 26.4 19.5 23.4 11.2 13.1 12.7 17.6 14.7 16.9 44.6 10.3 10.8 19.9 15.7 15.0 11.0 11.5 20.4 40.8 22.1 24.4 15.4 17.5 16.8 22.0 12.5 1.5 10.0 11.6 8.9 4.3 13.0 12.3 13.0 12.4 20.7 11.8 15.9 14.4 9.7 18.9 10.3 13.5 13.9 19.4 31.0 7.3 25.6 26.0 17.0 14.2 9.7 8.8 15.3 6.1 18.7 9.2 18.6 12.2 9.5 41.6 12.1 18.3 9.3 23.2 22.2 8.4 13.5 15.6 14.1 9.3 11.4 19.7 7.2 11.7 33.5 15.3 9.9 9.7 14.8 15.6 19.5 18.6 12.4 10.8 7.6 12.3 5.8 6.0 24.4 22.1 16.0 20.9 15.4 20.4 15.2 17.3 27.7 18.0 15.2 14.4 1.9 15.4 19.4 40.8 17.5 16.8 22.3 23.2 16.5 25.2 18.5 21.9 23.1 16.2 14.4 10.3 PTPN1 PTP1B ENSG00000196396 "Protein tyrosine phosphatase, non-receptor type 1" P18031 20 50510321-50585241 "Enzymes, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009329, HPA012542, CAB015217" Approved Enhanced "Endoplasmic reticulum" 11000 "Endoplasmic reticulum" "CAB009329: AB_2174944, CAB015217: , HPA012542: AB_1855915" "unprognostic (1.67e-1)" "unprognostic (7.78e-2)" "unprognostic (1.48e-1)" "unprognostic (1.05e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (2.98e-3)" "unprognostic (3.95e-2)" "unprognostic (2.40e-2)" "unprognostic (6.47e-3)" "unprognostic (5.87e-2)" "unprognostic (1.67e-1)" "unprognostic (1.66e-2)" "unprognostic (6.70e-2)" "unprognostic (2.99e-2)" "unprognostic (1.49e-1)" "unprognostic (2.58e-2)" 22.1 22.2 12.1 31.9 16.0 35.3 17.9 12.9 16.6 18.2 17.8 18.8 14.2 10.5 20.0 16.6 23.2 17.1 18.0 20.5 15.8 9.0 43.8 16.7 42.7 36.1 14.1 14.1 21.8 12.2 31.2 18.8 28.3 18.7 20.0 14.8 21.0 16.3 15.0 41.0 18.6 21.9 16.9 15.8 45.3 17.5 23.5 13.3 26.9 15.7 13.9 42.8 20.0 18.4 15.9 9.4 18.8 16.4 3.9 10.7 6.4 20.7 10.5 12.7 8.7 8.3 11.5 18.0 14.0 13.3 41.1 15.0 30.8 43.8 10.3 24.9 12.9 18.5 10.1 40.1 26.2 15.3 9.0 14.6 10.2 16.2 16.6 15.1 20.0 13.4 28.2 18.5 22.8 23.6 25.3 9.5 22.3 11.5 16.2 12.0 6.7 14.4 14.4 14.8 9.8 23.7 15.6 10.2 11.7 20.1 25.5 22.6 16.5 16.2 35.0 35.9 14.4 16.1 17.3 10.4 8.4 12.6 22.5 10.3 13.2 12.0 5.6 18.8 10.7 9.5 7.9 15.9 9.0 8.2 5.5 13.7 7.7 8.3 12.2 3.9 16.4 9.4 7.1 6.4 12.1 16.0 12.9 16.6 15.8 9.0 14.1 14.1 18.7 13.3 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase, non-receptor type 11" Q06124 12 112418351-112509913 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" 160000 Nucleoli "Nucleoplasm, Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 25.4 16.8 38.6 14.4 39.0 17.7 30.8 17.5 39.5 18.3 14.7 26.9 9.9 11.9 19.1 13.3 17.6 11.1 13.1 30.1 38.0 32.2 18.0 23.1 15.1 14.5 45.3 22.5 13.1 14.0 29.3 12.9 16.6 26.2 16.2 13.9 9.4 12.0 20.0 34.0 14.1 11.1 28.0 45.7 10.9 12.8 7.6 32.1 10.9 21.2 8.2 13.7 17.4 15.4 17.3 17.1 22.0 11.8 11.3 15.4 6.3 34.8 33.3 24.3 23.0 35.4 34.6 28.8 42.4 46.3 33.4 25.2 33.1 13.5 36.9 22.1 39.2 20.9 31.2 37.6 55.7 28.0 25.7 53.7 31.0 18.1 35.4 43.0 34.3 28.0 37.9 35.9 51.1 27.6 40.7 13.0 32.2 25.2 30.2 20.9 29.4 21.8 31.1 35.9 21.2 30.8 39.2 16.9 20.8 40.8 31.3 26.0 36.0 29.9 33.6 39.4 35.3 23.4 37.1 25.2 41.5 36.9 32.7 30.2 36.8 22.0 11.0 15.0 14.8 9.5 14.1 15.5 13.4 12.1 12.6 17.3 15.4 11.8 10.3 11.3 11.8 17.1 9.8 6.3 38.6 39.0 17.5 39.5 38.0 32.2 45.3 22.5 26.2 32.1 PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase, non-receptor type 12" Q05209 7 77537275-77640071 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" 1100000 "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavourable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavourable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavourable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavourable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" 29.6 15.1 14.3 20.5 19.6 29.7 25.1 15.7 22.7 20.0 28.9 8.1 13.8 8.8 20.7 9.6 22.0 18.1 19.8 45.6 17.3 12.6 16.9 14.8 34.7 17.4 15.3 13.4 19.0 10.7 12.4 19.8 36.0 18.6 14.1 13.8 9.9 12.8 17.1 17.6 17.6 14.6 23.0 24.0 25.0 14.4 13.9 17.7 9.7 16.7 11.9 12.9 23.2 61.2 2.5 3.9 9.9 4.9 12.8 3.8 2.8 17.5 10.8 25.7 13.1 18.1 18.9 13.8 18.4 23.4 14.5 20.7 5.3 27.6 2.1 5.9 21.5 12.6 8.6 18.4 29.3 5.1 4.8 11.0 10.9 21.7 17.7 6.2 7.4 15.4 20.6 31.5 40.8 30.6 13.2 3.1 46.2 12.0 0.8 17.4 20.7 12.4 3.7 20.6 1.1 24.9 9.5 3.2 17.1 22.6 20.7 17.9 10.0 23.0 22.2 31.4 19.0 11.4 34.6 3.2 1.7 5.4 18.5 16.3 54.4 3.7 4.2 6.6 3.6 2.9 1.4 2.5 1.2 2.7 3.9 1.1 0.6 3.8 9.9 12.8 4.9 0.3 1.5 2.8 14.3 19.6 15.7 22.7 17.3 12.6 15.3 13.4 18.6 17.7 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase, non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 3.0;MAIT T-cell: 2.3;memory CD4 T-cell: 2.2;non-classical monocyte: 4.9" "Group enriched" "Detected in many" 7 "monocytes: 4.9;T-cells: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 10.3 5.9 10.8 2.7 16.9 0.7 9.9 5.7 11.6 15.9 4.1 13.0 7.6 1.2 10.8 21.2 18.7 11.4 6.5 5.3 10.4 5.7 22.1 1.6 18.0 4.3 16.9 7.9 24.1 4.3 26.6 38.3 3.0 14.2 12.0 2.4 39.0 5.9 9.4 1.0 43.0 2.3 8.7 10.3 3.5 3.6 12.2 17.6 1.9 16.9 12.4 11.8 15.7 17.6 0.0 0.5 0.1 4.9 0.1 2.3 0.1 5.0 2.5 44.4 4.3 18.8 16.4 0.0 9.3 19.1 3.5 4.5 0.0 2.5 0.0 2.0 10.3 16.7 7.7 14.1 6.9 0.1 5.7 4.2 5.5 0.0 2.3 7.4 0.0 10.5 4.5 2.6 8.6 0.0 0.0 7.2 0.0 2.2 0.6 2.7 10.1 1.9 1.5 0.0 0.0 13.5 21.2 2.6 3.7 2.8 6.2 5.1 3.6 0.2 0.0 3.4 2.7 0.0 1.2 7.6 0.0 0.0 3.6 0.0 1.5 0.0 0.2 0.0 0.2 3.0 2.3 0.0 2.2 0.3 0.5 0.0 0.0 0.0 0.1 0.1 4.9 0.0 0.1 0.1 10.8 16.9 5.7 11.6 10.4 5.7 16.9 7.9 14.2 17.6 PTPN14 PEZ ENSG00000152104 "Protein tyrosine phosphatase, non-receptor type 14" Q15678 1 214348696-214552449 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011469, HPA053864, CAB069441" Uncertain Supported Nucleoplasm Nucleoplasm "CAB011469: AB_299202, CAB069441: , HPA053864: " "unprognostic (1.54e-1)" "unprognostic (8.19e-2)" "unprognostic (5.42e-5)" "unprognostic (1.42e-1)" "unprognostic (2.91e-1)" "unprognostic (5.97e-2)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (2.84e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (2.29e-4)" "unprognostic (7.43e-2)" "unprognostic (8.34e-3)" "prognostic unfavourable (5.16e-4)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "unprognostic (4.81e-3)" 13.6 10.0 3.0 6.5 2.4 0.2 15.0 0.8 3.7 13.6 8.5 2.6 11.0 1.0 15.4 8.0 8.6 9.2 9.7 7.0 3.5 1.9 11.2 2.0 12.2 6.6 2.4 1.3 11.8 5.0 6.3 4.0 13.2 4.9 10.6 2.9 7.2 9.2 23.4 21.6 18.8 3.5 9.4 4.3 5.3 5.7 8.3 2.4 1.4 8.1 6.9 3.7 12.4 17.7 1.0 0.5 1.9 0.4 1.0 0.6 0.1 8.7 3.9 3.2 4.6 5.6 9.5 9.4 9.9 9.3 7.6 6.4 7.9 4.6 0.0 11.1 23.1 7.8 4.3 11.1 13.1 0.1 3.3 0.8 11.1 1.4 10.1 0.1 0.4 7.1 11.6 13.2 21.3 14.7 0.0 0.1 18.4 0.9 0.1 0.1 7.0 4.2 0.1 16.0 0.0 13.7 4.4 0.0 0.7 12.3 8.1 5.0 8.0 0.3 26.2 17.9 7.0 6.4 14.1 0.5 0.0 0.0 9.6 0.1 14.9 1.3 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.4 0.1 1.0 0.5 0.6 1.9 1.0 0.4 0.5 0.6 0.1 3.0 2.4 0.8 3.7 3.5 1.9 2.4 1.3 4.9 2.4 PTPN18 BDP1 ENSG00000072135 "Protein tyrosine phosphatase, non-receptor type 18" Q99952 2 130356007-130375409 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012174, HPA053367" Uncertain Approved "Intermediate filaments" 550000 "Intermediate filaments" "CAB012174: AB_2173224, HPA053367: " "unprognostic (3.11e-3)" "unprognostic (2.89e-3)" "unprognostic (1.67e-3)" "unprognostic (1.73e-3)" "unprognostic (5.81e-3)" "unprognostic (3.08e-3)" "unprognostic (2.49e-2)" "unprognostic (1.28e-2)" "unprognostic (4.65e-1)" "unprognostic (2.10e-2)" "unprognostic (7.33e-2)" "unprognostic (5.65e-2)" "unprognostic (4.52e-2)" "unprognostic (1.00e-2)" "unprognostic (3.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.85e-3)" 12.8 7.1 11.0 16.7 13.5 18.9 22.3 26.8 13.7 15.3 22.8 6.6 25.7 16.6 9.3 11.0 11.3 13.3 21.3 7.5 9.8 8.5 13.9 19.2 16.9 29.2 8.4 9.5 7.8 28.9 6.4 11.0 9.4 6.9 17.8 19.3 7.9 18.5 24.0 11.0 6.9 28.8 10.5 9.1 37.7 16.0 3.3 9.1 1.6 13.0 7.1 35.5 11.0 10.7 7.6 7.4 6.2 17.1 2.8 6.6 10.2 5.8 3.9 1.5 7.9 9.8 6.8 16.3 3.0 2.7 3.9 4.3 7.8 8.9 21.8 3.0 7.2 6.7 6.9 6.7 3.8 9.9 3.8 7.9 4.7 9.1 5.1 7.7 21.4 8.0 5.5 4.2 5.9 7.3 7.3 16.6 7.4 11.3 1.4 13.3 1.6 4.2 13.3 4.5 29.5 7.7 3.6 10.1 2.6 5.3 18.9 8.6 6.5 11.3 6.8 5.5 6.3 3.0 2.7 2.6 0.7 20.9 8.5 7.0 6.0 6.2 7.8 6.1 6.6 10.8 4.1 7.6 4.4 6.3 6.7 4.5 2.7 5.4 4.9 2.8 17.1 7.4 5.6 10.2 11.0 13.5 26.8 13.7 9.8 8.5 8.4 9.5 6.9 9.1 PTPN2 "PTPT, TC-PTP, TCELLPTP, TCPTP" ENSG00000175354 "Protein tyrosine phosphatase, non-receptor type 2" P17706 18 12785478-12929643 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015004, HPA046176" Enhanced Supported Nucleoplasm Nucleoplasm "HPA015004: AB_2669131, HPA046176: AB_2679569" "unprognostic (5.83e-3)" "unprognostic (8.50e-2)" "unprognostic (5.85e-2)" "unprognostic (7.21e-3)" "unprognostic (8.94e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-1)" "unprognostic (2.37e-3)" "prognostic favourable (1.37e-4)" "unprognostic (1.06e-2)" "unprognostic (1.75e-2)" "prognostic unfavourable (1.20e-8)" "unprognostic (3.19e-1)" "unprognostic (6.84e-3)" "unprognostic (2.17e-1)" "unprognostic (4.61e-3)" 16.7 12.5 12.6 27.0 14.3 33.7 19.9 32.6 19.2 14.7 15.0 7.8 17.8 12.9 12.2 14.9 17.0 13.7 15.7 12.8 13.1 6.8 13.6 20.5 21.6 30.3 15.3 10.3 22.1 28.2 10.4 27.2 13.3 13.8 14.4 17.1 7.9 26.3 16.0 13.1 16.0 15.3 11.8 24.7 24.2 13.1 9.4 15.9 61.3 14.7 11.7 28.9 16.5 15.8 29.1 32.8 19.9 28.0 31.7 29.2 19.6 13.0 7.9 9.3 3.1 10.6 19.2 9.0 8.7 19.4 18.7 16.8 17.2 18.9 20.5 14.7 9.0 7.8 15.1 23.9 24.7 7.9 9.1 14.5 6.9 17.9 14.7 33.9 13.8 16.1 22.7 17.0 33.8 9.5 14.0 27.9 15.0 14.9 33.8 28.0 11.1 9.3 11.4 14.6 23.2 15.7 20.9 16.7 8.7 17.7 10.4 15.1 8.7 19.5 7.2 23.8 23.0 17.7 18.8 8.9 8.9 29.6 11.2 18.7 9.9 11.5 28.0 19.9 21.0 24.6 28.2 29.1 24.8 23.1 32.8 20.3 18.3 20.0 10.2 31.7 22.8 28.0 29.2 19.6 12.6 14.3 32.6 19.2 13.1 6.8 15.3 10.3 13.8 15.9 PTPN20 "bA142I17.1, bA42B19.1, CT126, DKFZP566K0524, PTPN20A, PTPN20B" ENSG00000204179 "Protein tyrosine phosphatase, non-receptor type 20" Q4JDL3 10 46911396-47002488 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.2" "Cell line enriched" "Detected in some" 5 "HDLM-2: 32.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA043337, HPA046896, HPA048310, HPA069148" Enhanced Supported "Centriolar satellite" "Centriolar satellite" "HPA043337: , HPA046896: , HPA048310: , HPA069148: " "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.04e-2)" "unprognostic (2.82e-3)" "unprognostic (6.78e-2)" "unprognostic (1.85e-1)" "unprognostic (8.44e-2)" "unprognostic (1.92e-1)" "unprognostic (1.53e-1)" "unprognostic (2.22e-2)" "unprognostic (2.83e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-2)" "unprognostic (1.75e-1)" "unprognostic (8.34e-2)" 1.2 9.7 1.0 1.9 3.1 0.0 3.4 3.4 5.4 0.8 1.3 1.0 5.0 1.1 1.4 0.4 3.4 1.0 0.5 8.8 1.4 3.4 4.3 0.6 0.6 0.2 2.4 0.8 1.6 3.9 0.0 2.3 0.3 11.7 1.1 1.5 1.2 7.8 3.2 11.0 5.6 1.0 0.6 1.2 1.0 1.0 13.2 0.0 0.2 1.9 1.7 0.5 1.0 1.0 2.8 2.2 0.0 0.0 2.3 3.1 0.7 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 1.9 2.4 0.0 0.0 0.0 32.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.5 0.8 5.9 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 4.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 2.8 1.7 0.4 1.1 0.6 2.2 3.1 0.0 2.3 0.0 2.2 1.3 0.7 1.0 3.1 3.4 5.4 1.4 3.4 2.4 0.8 11.7 0.0 PTPN21 "PTPD1, PTPRL10" ENSG00000070778 "Protein tyrosine phosphatase, non-receptor type 21" Q16825 14 88465778-88554733 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB011468, HPA073999" Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" "Plasma membrane, Cytosol" "Nucleoplasm, Golgi apparatus, Centriolar satellite" "CAB011468: AB_442979, HPA073999: " "unprognostic (2.18e-1)" "unprognostic (4.21e-2)" "unprognostic (7.60e-2)" "unprognostic (3.09e-2)" "unprognostic (4.60e-2)" "unprognostic (5.71e-2)" "unprognostic (6.55e-2)" "unprognostic (5.19e-3)" "unprognostic (6.62e-2)" "unprognostic (1.02e-2)" "unprognostic (8.71e-3)" "unprognostic (3.04e-3)" "prognostic favourable (3.16e-9)" "unprognostic (6.52e-2)" "unprognostic (2.69e-1)" "unprognostic (2.56e-1)" "unprognostic (7.67e-2)" 10.5 4.7 5.3 8.6 7.3 0.0 13.2 4.4 5.8 10.7 8.7 10.7 7.4 4.9 10.6 10.7 8.9 8.3 12.7 17.4 7.4 4.2 8.1 6.0 15.3 1.6 6.6 4.2 15.8 7.8 10.6 3.9 15.6 6.4 11.9 6.5 12.6 6.5 10.5 8.8 24.2 10.5 15.7 7.3 3.7 7.4 15.2 6.5 0.8 16.0 8.4 3.1 12.0 26.1 0.8 0.0 0.0 0.1 0.0 0.1 0.0 3.5 2.9 7.6 2.9 8.1 7.0 7.8 9.6 7.4 5.7 7.9 5.1 6.5 0.0 2.3 12.2 3.4 1.1 3.4 8.4 0.2 1.7 0.0 3.1 2.1 9.0 0.0 0.1 4.7 6.7 4.8 5.7 4.6 1.1 0.1 14.6 2.9 0.0 0.1 2.2 5.6 0.0 22.7 0.0 4.9 2.6 0.5 8.8 5.5 13.8 3.2 6.8 1.4 9.0 10.6 8.4 4.3 6.5 0.3 1.1 0.0 3.9 0.1 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.3 4.4 5.8 7.4 4.2 6.6 4.2 6.4 6.5 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase, non-receptor type 22" Q9Y2R2 1 113813811-113871759 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease mutation, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.6;lymphoid tissue: 46.0" "Cell line enhanced" "Detected in some" "Daudi: 32.9;HL-60: 13.0;U-266/70: 14.2;U-698: 17.6;U-937: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in single" 10 "cerebellum: 5.9" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 4.2 1.4 0.5 17.1 0.8 23.6 1.9 1.0 0.5 2.4 3.3 0.3 1.0 4.1 2.0 2.2 2.0 1.7 3.2 2.5 0.6 0.7 3.4 1.8 9.0 14.9 0.7 0.4 1.5 2.4 0.0 0.9 0.9 1.0 1.7 2.8 1.3 2.7 3.0 0.6 1.0 9.9 0.9 2.1 19.0 3.1 1.1 0.4 46.0 1.5 2.4 12.8 4.8 1.7 7.2 6.2 17.2 3.5 7.5 14.9 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.0 0.3 0.0 0.2 32.9 0.0 0.1 0.0 0.0 0.0 0.2 3.1 0.0 4.6 0.0 0.0 0.1 13.0 10.3 2.9 0.0 1.4 0.1 5.1 0.0 7.5 5.0 0.1 9.2 7.4 0.0 0.0 0.5 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 2.3 7.8 0.1 0.1 0.2 14.2 3.0 17.6 5.4 13.4 0.0 10.2 3.5 17.2 12.8 0.9 14.9 7.2 6.5 10.1 6.2 4.7 3.9 9.4 1.7 7.5 0.4 3.7 10.0 4.6 0.5 0.8 1.0 0.5 0.6 0.7 0.7 0.4 1.0 0.4 PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase, non-receptor type 23" Q9H3S7 3 47381011-47413441 "Enzymes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies" "Nuclear bodies" Nucleoplasm "HPA016845: AB_1855926" "unprognostic (1.17e-3)" "unprognostic (8.68e-2)" "unprognostic (2.56e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (1.07e-3)" "unprognostic (2.07e-2)" "unprognostic (9.55e-2)" "unprognostic (7.12e-2)" "unprognostic (5.67e-2)" "unprognostic (4.34e-2)" "prognostic favourable (1.82e-4)" "unprognostic (3.05e-2)" "unprognostic (4.40e-1)" "unprognostic (9.53e-2)" "unprognostic (4.68e-2)" 15.9 18.5 23.1 17.4 22.3 19.2 21.6 22.8 25.0 18.1 12.5 21.4 14.6 20.7 20.0 15.1 17.2 17.2 12.8 13.2 17.9 11.7 16.4 13.0 16.8 17.8 24.6 23.7 23.4 19.4 53.4 29.9 17.1 20.5 16.9 10.4 15.2 20.8 19.0 25.7 25.9 16.0 16.0 20.3 19.2 17.9 17.8 22.7 9.7 24.8 9.7 11.1 17.7 18.1 1.4 1.1 3.7 1.2 0.9 1.5 0.8 13.1 18.7 10.4 13.5 13.6 10.5 10.0 11.9 11.9 11.2 9.5 15.8 13.0 9.4 11.0 13.5 11.8 9.0 13.0 5.4 8.6 9.6 12.8 13.7 14.6 15.0 7.5 17.5 14.0 13.3 14.5 14.9 13.7 9.6 12.9 11.9 18.3 7.1 6.3 11.1 13.1 4.4 5.1 11.2 8.4 25.3 5.6 13.1 10.5 22.5 8.7 12.8 7.3 13.8 17.2 14.5 23.8 16.9 18.4 12.1 5.4 18.6 7.1 12.1 3.7 1.2 0.0 0.8 0.5 0.6 1.4 0.6 1.3 0.4 0.7 0.6 0.8 1.4 0.9 0.5 1.1 1.5 0.8 23.1 22.3 22.8 25.0 17.9 11.7 24.6 23.7 20.5 22.7 PTPN3 PTPH1 ENSG00000070159 "Protein tyrosine phosphatase, non-receptor type 3" P26045 9 109375466-109498313 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 38.1" "Cell line enhanced" "Detected in many" "HaCaT: 15.4;RPTEC TERT1: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038343, HPA046728" Approved "HPA038343: AB_10671741, HPA046728: " "prognostic unfavourable (6.71e-4)" "unprognostic (3.48e-1)" "unprognostic (3.64e-2)" "prognostic favourable (1.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (3.71e-2)" "unprognostic (5.38e-2)" "unprognostic (6.37e-2)" "unprognostic (3.57e-2)" "prognostic favourable (1.22e-15)" "unprognostic (1.64e-2)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (8.21e-2)" 2.7 1.9 3.4 4.8 5.0 0.0 4.8 2.1 11.1 4.4 9.4 2.0 10.7 7.6 3.2 13.4 10.3 6.4 6.3 12.1 3.1 2.8 28.8 21.1 4.9 0.5 1.2 3.9 1.5 17.0 10.6 4.9 14.5 4.5 4.7 6.5 3.8 13.1 13.6 38.1 18.8 18.8 0.8 0.9 0.9 5.9 2.1 0.0 1.1 9.4 7.2 9.5 4.1 5.5 0.6 0.3 2.8 0.6 0.3 0.3 0.1 6.4 8.0 0.3 2.1 0.0 0.0 12.7 1.4 0.0 1.7 1.9 4.2 10.5 0.0 1.5 0.1 15.4 2.2 9.0 1.8 3.5 4.9 0.0 3.8 4.3 0.0 0.0 0.1 0.1 9.7 2.2 4.7 0.0 0.0 0.1 0.1 8.1 11.0 1.9 1.0 6.0 0.0 2.6 0.1 20.7 12.4 5.2 1.1 3.5 13.1 0.0 7.5 1.0 0.0 0.6 5.1 0.8 0.0 6.3 10.3 0.0 6.8 0.0 4.6 0.4 0.6 0.8 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.6 0.3 0.3 2.8 0.3 0.6 0.3 0.1 0.1 3.4 5.0 2.1 11.1 3.1 2.8 1.2 3.9 4.5 0.0 PTPN4 PTPMEG ENSG00000088179 "Protein tyrosine phosphatase, non-receptor type 4" P29074 2 119759631-119983818 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 16 "NK-cells: 12.2;T-cells: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019351 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "HPA019351: AB_1855928" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-2)" "unprognostic (9.00e-2)" "unprognostic (9.57e-2)" "unprognostic (2.34e-1)" "prognostic favourable (5.16e-4)" "unprognostic (3.31e-2)" "unprognostic (3.34e-3)" "unprognostic (3.13e-1)" "unprognostic (1.10e-1)" "unprognostic (3.34e-2)" "unprognostic (1.74e-1)" "unprognostic (1.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.81e-1)" 6.8 6.9 10.0 5.9 12.2 7.3 7.2 37.4 16.9 9.6 5.5 7.2 5.2 8.1 7.2 6.6 6.9 8.9 6.3 8.9 10.2 8.4 12.0 6.6 8.0 7.9 7.3 13.1 8.9 6.3 11.6 16.3 4.1 8.3 6.2 4.0 7.1 7.9 6.6 11.2 5.8 5.5 4.7 7.3 9.2 8.9 7.7 6.5 18.9 22.5 6.8 6.5 5.3 5.8 0.5 0.3 0.9 0.4 12.2 19.3 4.7 7.3 4.3 5.7 7.6 5.1 5.3 9.7 3.3 9.4 1.9 5.2 6.4 11.4 5.3 8.0 3.7 6.5 4.4 5.2 5.1 12.3 3.7 3.6 4.1 6.1 3.4 3.7 2.7 4.8 9.8 8.8 4.0 8.3 6.2 5.4 5.0 5.6 5.1 4.3 7.5 7.1 3.5 9.8 7.4 6.9 10.0 7.4 9.2 4.6 5.9 3.8 2.8 2.4 10.4 0.2 6.5 2.2 4.0 9.3 13.0 6.7 4.9 0.2 3.1 0.2 0.2 0.9 19.3 0.3 15.6 0.5 9.6 15.1 0.3 0.5 3.2 11.0 0.7 12.2 0.4 0.3 5.6 4.7 10.0 12.2 37.4 16.9 10.2 8.4 7.3 13.1 8.3 6.5 PTPN5 "PTPSTEP, STEP, STEP61" ENSG00000110786 "Protein tyrosine phosphatase, non-receptor type 5" P54829 11 18727928-18792721 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "brain: 70.0" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HMC-1: 3.6;NTERA-2: 5.7" "Group enriched" "Detected in some" 6 "glioma: 1.6;testis cancer: 2.0" "Region enhanced" "Detected in many" "basal ganglia: 70.0" "Cell type enriched" "Detected in single" 9 "basophil: 1.5" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031014, HPA072091" Supported Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA031014: AB_10669550, HPA072091: " "unprognostic (1.23e-1)" "unprognostic (2.91e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-2)" "unprognostic (3.27e-2)" "unprognostic (2.13e-2)" "unprognostic (5.83e-3)" "unprognostic (3.59e-1)" "unprognostic (4.91e-2)" "unprognostic (2.59e-1)" "unprognostic (2.00e-1)" "unprognostic (3.58e-1)" "unprognostic (8.44e-4)" "unprognostic (4.21e-3)" "unprognostic (3.90e-2)" "unprognostic (9.39e-2)" "unprognostic (8.49e-2)" 2.5 1.6 16.3 1.1 70.0 1.1 1.2 0.9 47.5 1.5 1.1 0.4 0.0 1.1 1.2 1.0 1.3 1.7 1.4 4.3 9.1 8.6 1.1 0.9 2.7 1.1 3.5 16.0 2.5 1.2 1.5 0.5 0.9 6.1 1.6 1.4 0.0 1.3 1.7 1.8 1.0 1.4 1.4 2.1 1.3 1.3 3.4 9.3 0.0 1.2 0.0 1.0 1.5 0.3 0.1 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 5.7 0.3 0.0 0.1 0.1 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 70.0 0.9 25.1 9.1 8.6 3.5 16.0 6.1 9.3 PTPN6 "HCP, HCPH, PTP-1C, SHP-1, SHP1" ENSG00000111679 "Protein tyrosine phosphatase, non-receptor type 6" P29350 12 6946468-6961316 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 107.1;lymphoid tissue: 69.0" "Cell line enhanced" "Detected in many" "HEL: 28.1;HL-60: 24.9;HMC-1: 110.1;THP-1: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001466, CAB004572, CAB072845" Enhanced Supported Nucleoplasm,Nucleoli 7400000 Nucleoplasm Nucleoli "CAB004572: AB_628251, CAB072845: , HPA001466: AB_1855930" "unprognostic (4.28e-3)" "prognostic favourable (1.87e-4)" "prognostic unfavourable (5.42e-4)" "prognostic favourable (6.65e-4)" "unprognostic (6.54e-2)" "unprognostic (7.92e-2)" "unprognostic (2.36e-1)" "unprognostic (1.44e-2)" "unprognostic (6.93e-3)" "unprognostic (3.57e-1)" "unprognostic (1.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.60e-3)" "unprognostic (1.98e-3)" "unprognostic (2.60e-2)" "unprognostic (5.91e-2)" "prognostic favourable (2.64e-8)" 6.6 8.8 2.4 42.9 4.4 27.7 4.6 1.2 2.7 2.8 7.0 5.1 4.7 7.5 3.7 8.8 7.0 5.0 9.8 2.9 3.1 2.3 7.0 6.8 25.4 58.1 5.2 1.8 2.3 6.7 2.7 5.6 7.7 3.9 5.6 5.2 3.6 10.6 7.0 1.3 6.1 21.0 2.6 4.9 69.0 6.6 1.5 3.3 31.4 6.3 4.1 50.7 8.5 4.2 63.9 38.0 107.1 103.2 22.2 28.2 63.2 2.8 5.5 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 2.9 6.4 2.0 1.5 0.0 3.3 0.0 3.8 0.0 1.2 1.1 28.1 0.6 2.4 0.0 24.9 110.1 0.0 2.8 0.0 1.2 0.0 0.0 0.2 0.0 6.0 9.0 14.6 1.5 0.9 8.2 0.0 14.2 3.0 5.4 0.5 0.0 0.9 4.5 0.0 1.4 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 10.9 0.1 54.4 35.9 107.1 28.2 71.3 18.2 62.3 13.7 21.0 38.0 63.9 15.8 19.9 66.7 22.2 103.2 10.0 14.4 63.2 2.4 4.4 1.2 2.7 3.1 2.3 5.2 1.8 3.9 3.3 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase, non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.5;lymphoid tissue: 63.7" "Cell line enhanced" "Detected in some" "HEL: 16.4;HL-60: 35.6;HMC-1: 48.1;NB-4: 15.5;THP-1: 16.4;U-937: 25.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basal ganglia: 9.4;thalamus: 2.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 17.0;NK-cells: 9.9;T-cells: 10.6" "Region enriched" "Detected in single" 10 "basal ganglia: 5.5" "Region enriched" "Detected in all" 4 "basal ganglia: 10.9" "CAB009530, HPA019118" Approved "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favourable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favourable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavourable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 2.6 3.1 0.5 27.1 9.4 24.5 0.6 0.4 0.5 0.6 2.3 0.6 0.0 3.0 0.7 0.6 1.7 0.8 2.9 0.5 0.6 0.8 1.1 0.9 3.2 16.5 1.2 0.2 0.6 0.6 0.0 0.7 0.4 0.8 1.3 1.9 0.7 5.3 0.3 0.4 0.6 3.7 0.9 1.6 15.4 1.4 12.7 2.9 63.7 0.9 0.6 24.8 2.9 0.8 2.6 2.6 17.0 1.1 9.9 10.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 16.4 0.0 0.0 0.0 35.6 48.1 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.0 0.0 4.8 15.5 0.0 0.0 0.7 0.0 12.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16.4 0.0 0.0 0.1 0.0 0.0 7.2 1.8 10.3 0.0 25.7 0.0 11.5 1.1 17.0 10.6 1.1 9.5 1.9 7.1 10.5 2.0 2.6 5.3 6.4 7.1 9.9 0.4 2.6 9.0 2.8 0.5 9.4 0.4 0.5 0.6 0.8 1.2 0.2 0.8 2.9 PTPN9 MEG2 ENSG00000169410 "Protein tyrosine phosphatase, non-receptor type 9" P43378 15 75463251-75579289 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041922 Approved Approved Vesicles Vesicles "HPA041922: AB_10795269" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (7.38e-2)" "unprognostic (5.95e-2)" "unprognostic (3.93e-1)" "unprognostic (3.14e-1)" "unprognostic (9.25e-3)" "unprognostic (6.35e-2)" "prognostic favourable (2.49e-6)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.39e-1)" 16.8 12.8 15.0 11.8 17.7 9.2 15.7 11.1 20.0 17.4 22.4 10.5 12.0 17.0 18.9 16.4 10.9 16.4 13.5 12.2 13.1 14.6 17.9 14.0 16.0 12.6 11.6 12.4 16.0 12.3 16.6 12.5 18.9 13.2 16.9 19.5 18.4 14.6 21.9 6.8 11.8 30.6 17.6 15.6 15.6 13.4 8.7 7.5 16.3 34.4 8.0 13.9 14.7 15.3 3.3 5.9 4.6 5.7 6.7 7.2 2.9 9.1 11.0 17.2 11.5 12.9 14.2 5.7 13.7 21.4 17.4 15.9 6.6 13.9 14.8 11.1 23.4 13.8 37.0 15.8 17.6 18.3 9.4 8.3 7.9 7.0 19.4 12.5 12.8 18.4 16.6 13.9 21.8 14.5 5.5 5.4 19.6 6.0 8.9 11.8 15.8 5.6 17.5 8.5 4.1 21.9 14.8 6.8 14.1 19.5 10.9 21.0 5.6 21.7 16.7 16.7 5.4 10.9 14.6 8.0 8.3 13.8 9.7 19.1 16.4 4.6 4.3 4.2 7.2 5.7 5.7 3.3 5.0 6.1 5.9 2.3 2.1 3.9 0.7 6.7 5.4 3.9 3.1 2.9 15.0 17.7 11.1 20.0 13.1 14.6 11.6 12.4 13.2 7.5 PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase, receptor type A" P18433 20 2864184-3039076 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles 21000 Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: " "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.43e-3)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (3.24e-1)" "unprognostic (7.33e-2)" "unprognostic (1.16e-1)" "prognostic favourable (3.29e-6)" "unprognostic (1.25e-1)" "unprognostic (4.02e-1)" "unprognostic (1.60e-2)" "unprognostic (4.19e-1)" 21.9 18.5 55.6 14.3 48.6 16.4 23.3 44.5 56.0 29.7 19.7 37.5 9.4 14.7 26.3 18.7 22.7 26.5 21.3 14.0 45.9 41.1 22.1 13.5 21.6 16.9 38.0 46.7 28.6 14.9 41.5 23.4 29.0 52.5 23.5 20.0 18.5 16.7 21.8 8.2 21.0 15.3 25.7 52.6 17.9 16.3 27.4 30.4 20.6 32.4 8.5 20.4 22.9 19.2 7.7 5.7 7.9 6.7 6.2 11.0 3.7 20.5 12.6 36.3 11.1 40.2 73.4 7.7 15.5 30.3 19.2 23.5 15.0 28.6 13.5 12.2 20.7 22.1 14.6 22.1 21.7 20.8 9.4 19.2 5.3 19.0 14.4 19.2 9.1 32.8 22.9 15.8 16.7 26.5 19.2 17.3 19.0 8.4 22.2 21.8 14.0 10.1 17.0 17.6 16.8 16.4 16.0 20.1 19.3 15.0 25.5 23.0 15.9 16.5 18.9 17.1 8.5 19.1 13.6 12.7 17.6 17.8 7.9 18.2 16.0 7.9 4.8 7.5 11.0 4.8 9.0 7.7 7.4 7.9 3.7 5.1 7.4 9.0 6.0 6.2 6.7 5.7 8.1 3.7 55.6 48.6 44.5 56.0 45.9 41.1 38.0 46.7 52.5 30.4 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase, receptor type B" P23467 12 70515866-70637440 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "EFO-21: 11.1;HUVEC TERT2: 27.5;TIME: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 7 "memory B-cell: 3.5" "Lineage enriched" "Detected in single" 7 "B-cells: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" 6700000 "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: " "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favourable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favourable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 23.5 7.0 4.5 5.5 7.0 0.1 22.9 3.6 6.1 11.3 8.0 4.3 7.1 5.3 17.1 8.5 5.8 8.2 11.4 17.6 6.2 5.1 18.7 12.0 39.9 3.3 6.9 4.6 5.5 4.4 4.9 5.7 23.3 7.8 6.1 8.2 16.0 3.6 7.1 11.8 4.7 7.4 13.3 7.3 22.9 5.2 3.7 4.3 0.7 14.0 12.2 2.6 6.5 14.7 3.5 0.1 0.2 0.0 0.4 0.3 0.2 1.9 0.1 0.8 0.1 0.0 0.0 0.4 0.4 1.9 1.0 2.4 0.0 1.5 0.7 11.1 0.3 6.8 0.1 0.3 3.5 0.5 0.3 0.1 0.7 0.4 0.1 0.3 0.0 0.0 0.3 2.7 0.0 27.5 1.5 0.4 0.6 0.0 0.0 0.0 1.0 0.4 0.0 0.7 0.3 5.1 0.7 0.0 0.4 0.7 0.0 1.6 0.0 0.6 40.2 0.4 0.4 0.1 2.3 0.5 0.3 0.3 0.2 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 3.5 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.2 4.5 7.0 3.6 6.1 6.2 5.1 6.9 4.6 7.8 4.3 PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase, receptor type D" P23468 9 8314246-10612723 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1;parathyroid gland: 37.5" "Cell line enhanced" "Detected in some" "AF22: 23.0;HAP1: 5.0;HSkMC: 7.8;NTERA-2: 5.6;RH-30: 8.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" 2500000 Vesicles Nucleoplasm "HPA054829: " "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favourable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" 2.6 1.7 19.7 1.5 19.2 1.1 1.1 27.9 32.1 5.6 5.4 21.7 0.2 4.0 3.6 1.8 1.5 3.6 2.6 3.0 18.0 13.5 11.4 4.2 3.4 0.9 17.9 22.3 12.7 1.7 37.5 4.4 9.4 15.1 3.3 5.3 1.9 1.1 2.0 1.0 1.2 4.6 2.8 29.7 1.4 1.7 2.5 18.5 0.0 3.2 0.0 1.0 2.7 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 23.0 0.0 0.3 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 2.6 4.7 0.6 0.0 0.0 0.0 0.2 7.8 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 2.7 0.0 5.6 1.4 2.8 8.5 0.0 2.1 0.0 3.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.7 19.2 27.9 32.1 18.0 13.5 17.9 22.3 15.1 18.5 PTPRE PTPE ENSG00000132334 "Protein tyrosine phosphatase, receptor type E" P23469 10 127907061-128085855 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 91.0" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 19.9;NB-4: 15.0;TIME: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 91.0;plasmacytoid DC: 65.7" "Group enriched" "Detected in all" 11 "dendritic cells: 65.7;granulocytes: 91.0;monocytes: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015870, HPA021872" Supported Approved "Intermediate filaments" "Intermediate filaments" "HPA015870: AB_1855759, HPA021872: AB_1855760" "unprognostic (5.23e-2)" "unprognostic (1.37e-1)" "unprognostic (1.99e-1)" "unprognostic (7.11e-2)" "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (6.50e-2)" "unprognostic (4.49e-2)" "unprognostic (2.11e-1)" "unprognostic (2.56e-2)" "unprognostic (8.71e-3)" "unprognostic (2.00e-1)" "prognostic unfavourable (4.08e-5)" "unprognostic (1.52e-1)" "unprognostic (6.71e-3)" "unprognostic (2.49e-2)" "unprognostic (5.59e-2)" 16.8 18.5 12.5 24.0 12.5 39.5 11.0 7.4 15.3 4.8 9.2 14.5 1.6 9.6 5.1 8.1 8.8 6.2 10.7 12.3 15.0 12.2 4.4 4.8 22.5 20.0 12.5 6.5 4.3 3.1 3.4 6.5 8.0 9.8 4.5 9.8 4.8 7.0 3.1 1.9 4.9 12.7 7.7 14.3 26.4 7.7 4.3 10.9 11.4 6.6 6.1 12.2 10.0 5.0 1.2 65.7 91.0 25.5 4.0 5.4 4.9 2.0 0.4 0.2 0.0 1.2 0.2 3.6 0.0 0.0 0.8 1.7 0.8 12.0 1.5 1.3 1.0 1.1 1.0 5.8 0.3 1.8 0.9 0.1 0.7 0.0 2.0 7.4 5.6 0.4 3.3 2.9 5.9 19.9 0.0 0.9 1.2 1.8 2.2 15.0 0.1 0.7 8.8 1.2 2.9 3.3 8.6 0.0 1.2 3.4 0.6 0.1 0.3 9.4 37.5 0.8 0.8 3.7 4.1 0.4 0.6 2.1 5.5 5.8 0.0 17.4 25.5 19.3 5.4 9.0 3.2 0.9 2.4 3.6 13.3 1.2 1.7 2.9 91.0 4.0 6.8 65.7 3.5 4.9 12.5 12.5 7.4 12.7 15.0 12.2 12.5 6.5 9.8 10.9 PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase, receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 53.7;SK-BR-3: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" 95000000 "Golgi apparatus" "HPA012710: AB_1855933" "unprognostic (8.20e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (9.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.11e-1)" "prognostic unfavourable (3.47e-4)" "unprognostic (4.59e-1)" "unprognostic (1.51e-1)" "unprognostic (4.97e-2)" "unprognostic (4.68e-2)" "unprognostic (7.07e-2)" "unprognostic (1.99e-2)" "prognostic favourable (7.03e-4)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.58e-1)" 37.1 5.5 22.4 10.4 18.1 0.9 30.7 6.8 19.5 14.2 34.3 16.8 34.4 30.7 12.3 33.4 41.4 32.2 20.0 6.3 17.2 15.0 12.0 45.6 15.7 5.8 17.2 18.5 10.4 25.3 17.5 10.3 38.1 16.1 30.9 23.1 5.9 41.9 23.6 2.9 46.8 35.5 16.8 11.2 2.0 21.8 4.3 15.8 4.6 12.5 11.7 14.9 21.4 21.3 0.9 0.0 0.2 0.0 0.0 0.0 0.7 30.4 14.6 9.6 11.3 2.2 0.1 53.7 17.5 7.0 14.5 12.4 15.5 41.5 0.0 4.9 7.6 23.9 11.1 38.5 17.6 0.3 13.9 0.1 10.0 14.1 6.8 0.2 0.2 2.2 22.2 20.8 34.6 21.5 4.7 1.4 5.3 17.6 0.2 0.2 14.5 4.0 10.6 17.0 0.7 5.6 46.1 14.3 5.3 17.4 61.4 2.3 17.7 3.2 16.9 0.3 23.2 1.4 23.3 0.6 0.5 0.0 1.4 0.7 45.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 22.4 18.1 6.8 19.5 17.2 15.0 17.2 18.5 16.1 15.8 PTPRG "PTPG, RPTPG" ENSG00000144724 "Protein tyrosine phosphatase, receptor type G" P23470 3 61561569-62297613 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 35.5;HSkMC: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000546, HPA064237" Uncertain Approved "Plasma membrane" 520000000 "Plasma membrane" "HPA000546: , HPA064237: " "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (3.26e-1)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-1)" "prognostic favourable (3.10e-6)" "unprognostic (9.91e-2)" "unprognostic (3.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" 22.2 18.0 12.9 10.1 10.7 1.2 26.1 8.1 16.4 17.2 13.9 5.2 12.0 5.6 15.8 19.0 6.4 13.1 15.7 12.4 24.5 9.9 20.2 8.2 38.9 10.2 8.3 10.5 16.6 6.0 58.6 11.9 13.1 15.1 11.3 8.9 23.3 7.9 17.2 19.2 6.6 8.4 17.4 12.7 9.2 8.7 11.4 5.0 0.1 21.7 7.0 3.2 10.0 14.6 1.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.1 11.4 0.0 35.5 18.1 5.5 7.0 11.6 7.5 10.2 5.3 0.2 0.2 4.1 8.3 0.1 5.5 5.5 12.0 0.6 3.1 0.5 0.0 6.1 11.9 2.9 0.0 26.3 2.2 10.7 13.0 8.1 0.0 7.0 6.8 3.0 0.0 0.0 7.0 0.0 4.6 3.5 0.2 7.8 3.3 0.8 1.8 1.7 0.0 2.7 0.0 0.1 18.5 10.6 10.1 16.9 5.9 2.2 2.6 0.0 8.1 1.3 12.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 12.9 10.7 8.1 16.4 24.5 9.9 8.3 10.5 15.1 5.0 PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase, receptor type H" Q9HD43 19 55181248-55209506 "Enzymes, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "gallbladder: 29.6;intestine: 84.3;lymphoid tissue: 21.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 8.0;HHSteC: 10.4;K-562: 12.1;PC-3: 8.2;SK-MEL-30: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in single" "non-classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042300 Approved Mitochondria Mitochondria "HPA042300: AB_10796900" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" 0.5 8.9 0.5 5.2 0.7 0.0 0.5 0.5 1.0 0.7 39.9 0.6 0.5 30.1 0.5 0.5 0.6 0.0 29.6 0.5 1.3 1.6 0.6 7.8 0.6 0.5 3.0 0.5 0.6 2.8 0.0 3.0 0.6 0.5 1.0 9.6 0.6 0.5 0.5 0.5 0.0 84.3 0.7 6.9 21.2 10.2 0.5 0.5 0.5 0.5 1.0 0.8 1.1 2.4 0.0 0.7 0.0 1.5 0.0 0.0 0.0 5.6 3.5 0.0 1.4 1.1 3.1 0.1 0.1 3.0 0.6 1.2 1.5 8.0 0.0 0.3 0.5 0.0 0.0 0.0 0.7 0.0 0.1 0.4 0.1 4.0 10.4 0.0 4.1 0.8 2.5 2.0 3.1 0.1 12.1 0.5 0.0 0.0 0.0 0.2 0.0 8.2 0.0 0.0 0.4 0.0 0.0 0.3 0.8 0.0 3.6 18.2 0.0 1.6 0.0 0.8 1.2 0.4 0.0 0.0 3.0 0.0 0.9 0.1 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.5 0.7 0.5 0.5 1.3 1.6 3.0 0.5 0.5 0.5 PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase, receptor type J" Q12913 11 47980558-48170841 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 25.3;RPTEC TERT1: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in all" 4 "granulocytes: 12.2;monocytes: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved "Intracellular and membrane" 840000000 "HPA006026: AB_1078446" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "unprognostic (9.64e-3)" "unprognostic (3.79e-3)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "prognostic favourable (1.13e-5)" "unprognostic (1.09e-2)" "unprognostic (7.98e-2)" "unprognostic (9.18e-2)" "unprognostic (2.00e-1)" 5.6 3.7 10.4 17.7 13.9 22.6 5.6 4.9 9.5 6.1 9.0 8.8 12.3 8.4 3.9 7.6 2.9 5.0 6.7 5.2 9.5 9.2 13.3 12.2 12.2 22.6 10.8 9.4 3.0 9.1 21.1 14.5 20.3 8.3 7.8 8.1 12.9 12.9 9.0 4.6 4.3 13.4 5.5 6.7 33.0 13.8 3.1 9.9 6.7 18.8 0.9 9.7 6.0 3.9 1.0 1.8 12.2 5.3 1.2 2.1 0.9 3.5 13.4 5.9 3.2 0.9 2.1 2.0 3.6 2.6 6.3 4.7 0.8 19.8 3.3 25.3 9.1 2.7 9.2 0.9 7.7 21.7 2.5 0.9 16.6 1.2 5.8 1.2 20.6 1.5 0.3 1.7 0.4 3.8 1.2 2.1 2.2 7.6 0.0 7.4 4.6 2.1 0.7 0.7 1.7 24.6 5.2 4.0 1.2 10.0 5.7 9.0 6.3 9.1 12.4 5.0 5.2 10.0 10.9 0.5 0.7 5.5 5.7 3.8 18.1 0.9 1.5 3.4 2.1 2.5 1.4 1.0 1.2 1.5 1.0 0.7 1.0 1.3 12.2 1.2 5.3 1.8 1.1 0.9 10.4 13.9 4.9 9.4 9.5 9.2 10.8 9.4 8.3 9.9 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase, receptor type K" Q15262 6 127968779-128520674 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.3;naive B-cell: 4.8;naive CD8 T-cell: 1.6" "Group enriched" "Detected in many" 7 "B-cells: 4.8;T-cells: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" 13000000 "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: , HPA054822: " "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favourable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 12.0 5.2 18.6 10.7 20.3 1.2 20.9 4.7 24.4 12.2 21.9 25.6 11.2 25.7 12.1 10.3 9.1 13.2 29.6 11.4 17.2 12.6 13.3 23.6 17.4 5.7 20.5 19.3 15.6 25.7 11.4 12.2 17.4 14.9 16.3 23.4 3.9 18.3 17.5 9.1 13.5 27.4 14.6 17.1 6.4 24.6 2.7 23.7 15.3 10.1 6.5 7.6 18.4 15.1 4.8 0.0 0.0 0.0 0.4 1.6 0.2 4.4 4.8 2.9 0.2 6.1 8.2 2.9 12.1 23.5 5.0 4.6 8.0 3.7 0.0 3.7 11.1 12.7 3.0 9.6 7.1 13.4 4.9 0.1 7.4 11.1 7.5 0.0 0.4 6.0 8.9 10.5 14.4 13.7 0.0 0.2 12.3 9.0 6.8 0.0 3.0 6.2 24.5 6.2 0.8 12.4 9.2 15.3 0.0 12.5 14.0 0.7 3.8 0.3 23.1 7.9 5.5 15.3 10.9 0.1 1.6 0.0 10.1 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 4.8 0.4 1.6 0.0 0.4 0.0 0.0 0.1 0.2 18.6 20.3 4.7 24.4 17.2 12.6 20.5 19.3 14.9 23.7 PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase, receptor type M" P28827 18 7566782-8406861 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 34.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "memory CD8 T-cell: 7.2" "Group enriched" "Detected in many" 50 "dendritic cells: 2.7;T-cells: 7.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" 76000000 "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: " "unprognostic (2.59e-1)" "prognostic unfavourable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favourable (1.07e-4)" 31.4 14.1 9.5 6.3 22.2 0.6 23.6 10.4 17.2 11.0 13.6 6.2 28.1 4.7 15.4 10.9 8.1 13.6 18.1 33.5 10.5 15.0 16.9 6.5 22.0 7.8 8.5 12.0 15.7 7.6 16.3 21.9 18.3 23.2 10.6 6.6 18.3 7.4 21.8 26.0 7.3 8.7 14.1 9.3 12.1 11.0 12.2 9.1 2.9 31.1 7.3 6.3 18.6 25.3 0.0 2.7 0.0 0.0 0.0 7.2 1.4 1.5 11.3 5.4 0.0 34.8 24.1 13.1 13.8 12.2 9.3 13.8 10.3 2.4 0.0 13.6 16.6 0.1 0.0 4.8 12.9 0.1 2.5 0.0 7.5 5.0 9.9 0.0 0.1 27.4 10.2 5.1 14.7 9.3 0.0 4.7 7.4 0.2 4.5 0.1 0.9 2.5 0.1 4.7 20.9 22.8 19.4 0.4 3.0 0.4 0.0 11.6 0.0 0.0 9.6 19.2 12.1 9.1 2.4 0.4 0.1 0.0 16.4 0.0 3.5 0.0 0.0 0.0 4.5 0.0 1.8 0.0 6.0 7.2 0.1 0.0 1.7 3.1 0.0 0.0 0.0 2.7 1.0 1.4 9.5 22.2 10.4 17.2 10.5 15.0 8.5 12.0 23.2 9.1 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase, receptor type N2" Q92932 7 157539056-158587788 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6;pancreas: 51.3" "Cell line enhanced" "Detected in some" "AF22: 15.3;HDLM-2: 21.5;NB-4: 22.1;SCLC-21H: 12.2;SH-SY5Y: 12.4;THP-1: 10.8;U-87 MG: 15.1" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 14.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavourable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favourable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 2.1 10.5 20.1 1.7 33.9 1.0 1.1 6.2 40.6 1.7 4.6 2.9 0.0 5.1 2.0 2.9 1.5 6.9 4.7 1.9 18.2 21.3 2.0 1.2 3.1 2.1 11.3 22.3 5.8 51.3 0.5 20.0 1.5 10.3 10.2 3.7 1.5 3.4 2.6 0.8 0.7 4.2 1.6 5.3 7.7 24.2 2.2 5.2 0.0 5.6 0.3 1.7 2.8 0.6 3.4 1.3 14.8 1.1 1.5 3.5 1.1 0.0 0.2 15.3 1.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.6 0.2 0.0 0.4 0.0 0.0 21.5 0.2 0.0 0.0 2.5 0.6 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 6.3 22.1 3.0 0.7 0.0 0.7 0.1 0.0 0.0 12.2 12.4 0.0 0.0 0.0 0.0 10.8 3.2 5.0 1.9 0.0 0.3 0.1 0.0 0.0 15.1 9.0 3.6 8.7 1.1 1.6 0.9 0.1 0.3 2.3 1.5 1.1 1.3 3.4 1.4 0.9 14.8 1.5 0.0 0.2 3.5 1.1 20.1 33.9 6.2 40.6 18.2 21.3 11.3 22.3 10.3 5.2 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase, receptor type O" Q16827 12 15322397-15597399 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;intestine: 28.5;kidney: 21.6" "Cell line enhanced" "Detected in some" "NTERA-2: 9.3;SCLC-21H: 5.7;SH-SY5Y: 11.2;THP-1: 4.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.2;intermediate monocyte: 10.5;memory B-cell: 8.3;myeloid DC: 7.4;naive B-cell: 7.0;naive CD4 T-cell: 2.9;non-classical monocyte: 10.5;plasmacytoid DC: 9.5" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory region: 215.3" "Low region specificity" "Detected in many" HPA034525 Enhanced "Intracellular and membrane" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 3.3 1.2 16.2 3.1 26.1 0.6 1.1 1.0 15.3 1.7 10.4 1.5 0.0 2.0 4.5 2.1 0.8 1.2 1.6 0.7 11.3 10.6 21.6 1.6 6.7 3.2 4.8 8.8 0.7 0.6 0.6 3.8 4.4 4.0 0.7 28.5 1.1 0.8 1.1 0.5 0.7 1.9 7.1 2.6 3.6 1.0 0.9 3.5 0.0 0.5 0.0 3.5 1.7 0.5 8.3 9.5 0.0 10.5 0.1 2.9 2.7 0.0 0.1 0.5 0.4 0.6 0.1 0.2 0.0 0.0 0.9 2.2 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.3 0.1 0.2 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.7 9.3 0.1 0.0 0.0 0.1 0.2 0.3 5.7 11.2 1.3 0.0 0.1 0.1 4.6 0.0 0.1 0.4 0.0 0.4 1.4 0.1 0.4 0.1 0.3 1.7 0.0 5.2 0.0 0.0 10.5 0.0 8.3 1.7 0.4 7.4 7.0 2.9 1.3 0.0 0.1 10.5 9.5 1.3 2.7 16.2 26.1 1.0 15.3 11.3 10.6 4.8 8.8 4.0 3.5 PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase, receptor type R" Q15256 12 70638073-70920843 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 56.1" "Group enriched" "Detected in some" 5 "HDLM-2: 14.0;RT4: 26.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 56.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "cerebellum: 100.5" "Low region specificity" "Detected in all" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: AB_298890, HPA011851: AB_1855939, HPA071067: " "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.63e-3)" "unprognostic (3.48e-5)" "unprognostic (5.44e-3)" "unprognostic (1.77e-3)" "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (1.37e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (2.72e-1)" "prognostic favourable (1.40e-5)" 0.4 3.8 18.8 1.6 11.3 0.3 0.4 56.1 20.9 0.5 11.2 0.1 0.0 5.1 8.4 0.3 0.4 0.5 1.9 0.4 8.6 4.9 0.4 0.4 0.4 0.4 1.3 13.2 0.4 0.6 0.3 0.9 0.7 3.3 0.5 7.8 0.8 0.4 2.1 0.4 0.4 11.3 4.9 3.1 0.4 4.4 0.4 1.4 0.0 0.4 0.0 0.3 4.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.5 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 26.7 0.1 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 18.8 11.3 56.1 20.9 8.6 4.9 1.3 13.2 3.3 1.4 PTPRS ENSG00000105426 "Protein tyrosine phosphatase, receptor type S" Q13332 19 5158495-5340803 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 40.7;HaCaT: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 82 "plasmacytoid DC: 13.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" 92000000 "Plasma membrane, Cytosol" "HPA054747: " "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favourable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavourable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 59.1 17.3 14.4 9.4 14.8 3.1 32.0 27.6 53.3 28.7 11.4 29.6 14.4 4.6 21.4 15.4 13.3 24.0 22.2 18.6 15.9 15.1 10.7 6.9 13.9 8.6 20.5 12.1 29.2 38.4 10.5 16.6 4.3 12.0 23.1 3.6 28.9 21.5 20.1 11.9 23.8 6.5 17.5 13.8 8.3 12.7 10.8 18.7 4.4 21.1 7.2 7.5 19.1 22.7 0.0 13.4 0.0 0.0 0.0 0.1 0.0 3.6 20.9 18.9 40.7 8.7 7.1 2.5 6.3 7.5 7.7 6.3 0.2 2.0 0.0 15.0 10.6 41.3 5.0 0.0 3.4 0.4 8.0 0.0 8.6 13.0 4.0 0.0 4.7 7.5 1.8 1.6 0.3 0.2 5.8 0.0 3.1 15.4 1.6 3.9 10.6 8.9 0.0 4.2 0.0 1.5 7.3 14.5 19.9 6.0 1.1 11.5 7.3 1.5 0.8 6.9 11.9 15.7 7.6 2.1 0.0 12.0 3.5 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 14.4 14.8 27.6 17.6 15.9 15.1 20.5 12.1 12.0 18.7 PTPRT "KIAA0283, RPTPrho" ENSG00000196090 "Protein tyrosine phosphatase, receptor type T" O14522 20 42072752-43189970 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 23.5;fallopian tube: 17.0" "Cell line enhanced" "Detected in some" "BEWO: 4.5;RPMI-8226: 1.2;SCLC-21H: 2.9;U-266/70: 1.0" "Cancer enhanced" "Detected in many" "breast cancer: 5.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017336, CAB069423" Approved "CAB069423: AB_1622602, HPA017336: AB_1855943" "unprognostic (7.17e-3)" "unprognostic (1.02e-1)" "unprognostic (5.61e-3)" "unprognostic (1.08e-2)" "unprognostic (5.95e-2)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (1.31e-2)" "unprognostic (6.93e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-6)" "unprognostic (3.16e-1)" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.17e-1)" 0.6 0.8 5.0 0.6 11.1 0.5 4.6 1.6 23.5 1.6 0.7 0.9 0.0 1.2 0.5 1.8 0.5 17.0 0.7 0.8 4.7 6.5 0.6 0.9 2.1 1.0 2.2 12.6 0.5 0.9 0.5 4.1 4.6 5.1 0.8 0.6 0.5 2.0 4.6 0.5 0.8 1.0 0.5 1.4 0.7 1.8 2.8 0.9 4.9 0.5 0.0 1.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 11.1 1.6 22.6 4.7 6.5 2.2 12.6 5.1 0.9 PTPRU "FMI, hPTP-J, PCP-2, PTP, PTPRO" ENSG00000060656 "Protein tyrosine phosphatase, receptor type U" Q92729 1 29236516-29326813 "Enzymes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 39.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB011476, HPA039832" Approved "CAB011476: AB_442989, HPA039832: AB_10793923" "unprognostic (7.81e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-3)" "unprognostic (6.13e-2)" "prognostic unfavourable (7.92e-4)" "prognostic unfavourable (8.32e-4)" "unprognostic (3.17e-1)" "unprognostic (1.83e-2)" "unprognostic (1.13e-1)" "unprognostic (4.55e-3)" "unprognostic (3.39e-3)" "unprognostic (6.83e-2)" "unprognostic (1.19e-2)" "unprognostic (6.82e-2)" "unprognostic (4.92e-2)" "unprognostic (3.34e-1)" "unprognostic (2.05e-1)" 6.0 3.2 3.1 1.7 5.8 0.6 16.0 6.7 12.7 24.8 3.7 2.6 6.1 1.3 9.5 4.7 3.9 14.5 7.0 8.9 4.5 5.1 3.9 7.0 11.4 1.2 5.2 5.3 12.2 12.0 12.1 8.1 14.3 21.4 11.0 2.3 18.7 11.3 17.9 14.7 7.3 1.7 6.5 6.6 2.4 4.5 4.4 0.9 0.3 4.9 2.1 2.0 12.2 17.6 0.4 0.0 0.0 0.5 0.0 0.2 0.0 3.1 4.3 0.2 0.6 12.1 0.4 39.7 3.4 3.0 0.1 0.2 3.7 14.1 0.5 6.7 0.6 17.1 15.7 11.0 0.0 0.2 7.9 0.6 4.8 15.7 5.1 0.0 0.7 5.6 5.9 0.0 1.0 0.1 0.1 0.5 3.1 5.2 0.2 0.1 6.5 2.0 0.0 4.6 0.2 4.8 15.8 13.4 17.4 3.4 10.8 2.3 6.4 0.7 2.8 0.6 3.9 1.0 0.4 0.3 0.4 0.0 7.8 0.7 0.8 0.0 0.2 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 3.1 5.8 6.7 12.7 4.5 5.1 5.2 5.3 21.4 0.9 PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase, receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 118.1" "Group enriched" "Detected in some" 9 "AF22: 92.1;NTERA-2: 25.6;WM-115: 40.3" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" 950000 Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavourable (9.36e-4)" 2.0 2.5 33.1 2.3 44.1 1.5 4.0 15.4 118.1 2.4 2.2 19.3 0.0 1.9 1.6 2.0 7.0 1.7 1.9 2.0 39.6 15.9 1.6 1.6 2.1 1.5 18.6 17.8 2.0 3.3 1.5 1.6 1.6 67.6 2.1 2.3 0.8 2.4 2.0 1.5 19.3 1.9 2.4 76.6 2.1 9.8 1.7 23.6 0.0 1.5 1.8 3.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 1.1 0.0 0.1 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 44.1 15.4 39.6 39.6 15.9 18.6 17.8 67.6 23.6 PTRH1 "C9orf115, PTH1" ENSG00000187024 "Peptidyl-tRNA hydrolase 1 homolog" Q86Y79 9 127690348-127724873 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021223 Uncertain "HPA021223: AB_1845798" "unprognostic (6.58e-2)" "unprognostic (7.01e-3)" "unprognostic (3.46e-3)" "unprognostic (2.53e-2)" "unprognostic (7.05e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (3.90e-2)" "unprognostic (1.74e-1)" "unprognostic (6.58e-3)" "unprognostic (8.67e-2)" "unprognostic (4.08e-2)" "unprognostic (5.98e-3)" "unprognostic (5.74e-4)" "unprognostic (1.38e-2)" "unprognostic (1.91e-1)" "unprognostic (1.72e-2)" 14.9 15.0 12.5 8.3 11.9 7.1 9.1 3.9 13.7 9.4 7.8 10.7 12.9 7.7 7.8 16.1 7.8 9.9 12.6 13.1 10.7 9.4 14.5 19.3 7.5 14.7 11.6 8.5 6.2 24.7 8.8 11.0 7.2 8.9 9.9 4.0 8.3 9.3 9.9 13.0 15.1 5.8 6.4 6.2 9.4 12.4 16.1 6.2 7.1 18.8 9.1 5.7 9.4 5.6 8.7 11.4 5.6 14.4 10.5 29.4 12.8 15.7 7.1 1.6 4.3 2.3 3.0 12.4 10.5 2.9 4.0 2.2 3.6 6.0 6.0 14.2 4.3 17.5 1.3 7.6 1.2 8.6 2.4 2.6 8.8 7.1 6.8 3.9 7.1 2.5 8.0 4.9 5.1 8.0 6.7 4.8 4.6 14.5 7.0 5.8 2.2 32.0 6.0 3.5 13.5 7.3 3.5 7.0 6.5 11.3 13.6 7.9 12.2 2.5 9.5 5.9 8.1 20.8 6.5 14.3 7.6 3.9 7.9 3.0 7.0 2.5 13.2 5.6 29.3 14.4 29.3 8.7 15.1 29.4 11.4 7.2 11.1 25.5 1.7 10.5 7.5 10.4 14.2 12.8 12.5 11.9 3.9 13.7 10.7 9.4 11.6 8.5 8.9 6.2 PTRH2 "BIT1, CFAP37, CGI-147, PTH2" ENSG00000141378 "Peptidyl-tRNA hydrolase 2" Q9Y3E5 17 59674636-59707626 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Apoptosis Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012897 Supported Supported Mitochondria Mitochondria "HPA012897: AB_1855949" "unprognostic (2.26e-1)" "unprognostic (2.80e-2)" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.38e-2)" "prognostic unfavourable (1.50e-4)" "unprognostic (6.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.59e-3)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.01e-8)" "unprognostic (5.43e-3)" "unprognostic (6.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.49e-2)" 15.9 22.9 17.1 12.4 17.1 9.9 20.7 12.5 22.1 15.6 17.2 11.8 16.3 11.6 14.3 36.7 16.4 13.8 13.1 12.6 19.3 17.8 14.8 34.7 12.1 12.5 16.7 15.2 14.2 19.9 10.3 18.3 13.6 21.0 15.9 20.7 8.1 13.7 18.7 23.3 11.4 11.0 16.8 17.1 15.5 14.3 15.7 18.1 9.0 11.8 13.5 16.9 13.0 10.5 15.6 21.6 12.6 29.3 13.1 15.5 13.0 19.8 37.9 12.2 11.1 23.2 20.0 13.1 19.1 16.9 16.4 24.0 24.4 15.6 14.4 29.0 16.0 19.8 26.2 24.6 23.9 27.7 35.7 25.7 19.7 44.8 35.8 22.7 14.6 22.5 32.1 25.4 29.6 27.2 28.6 16.1 24.3 47.9 19.4 18.5 10.5 30.0 10.6 20.5 21.0 27.3 28.6 15.8 20.5 9.9 10.8 23.4 25.2 16.2 17.9 21.4 21.7 12.8 20.7 20.9 23.2 21.4 14.1 14.2 16.3 1.9 25.8 1.1 9.2 24.4 12.4 15.6 10.8 10.4 18.5 13.1 15.5 11.1 12.6 13.1 29.3 21.6 12.3 13.0 17.1 17.1 12.5 22.1 19.3 17.8 16.7 15.2 21.0 18.1 PTRHD1 "C2orf79, LOC391356" ENSG00000184924 "Peptidyl-tRNA hydrolase domain containing 1" Q6GMV3 2 24789734-24793382 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019951 Approved Approved Nucleoplasm 55000 Nucleoplasm "HPA019951: AB_1853109" "unprognostic (1.28e-2)" "unprognostic (5.79e-2)" "unprognostic (6.34e-2)" "unprognostic (1.34e-2)" "unprognostic (2.61e-2)" "unprognostic (3.99e-1)" "unprognostic (8.84e-3)" "unprognostic (1.26e-1)" "unprognostic (3.69e-1)" "unprognostic (8.31e-3)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "prognostic unfavourable (2.31e-4)" "unprognostic (2.93e-1)" "unprognostic (1.55e-1)" "unprognostic (1.51e-1)" "unprognostic (5.76e-2)" 8.2 20.0 19.4 10.8 16.2 20.4 13.3 4.6 13.0 6.7 13.6 8.5 7.8 16.1 5.6 11.9 12.7 8.2 10.2 15.8 15.6 14.4 11.3 16.0 9.2 17.6 16.9 8.8 8.5 28.1 2.7 8.4 12.2 10.4 11.0 9.4 7.6 25.9 7.5 30.1 10.3 15.0 5.6 15.5 10.4 11.7 25.2 6.9 17.5 15.6 19.9 12.9 8.3 8.4 29.1 44.1 8.2 27.9 14.5 23.7 26.1 8.0 19.4 6.3 2.7 3.6 8.0 10.9 5.9 5.7 7.8 5.0 19.1 7.7 6.8 2.5 6.3 5.4 5.2 5.5 2.6 9.2 35.0 12.3 9.4 20.8 7.4 10.0 11.5 7.6 4.5 3.6 4.0 7.2 12.2 5.4 5.7 17.7 8.2 18.7 13.2 11.7 6.7 19.2 11.2 9.0 15.2 9.8 15.2 6.5 8.8 7.6 8.5 7.6 11.8 6.6 10.3 3.1 5.0 4.3 13.1 7.3 6.2 6.3 4.5 8.2 27.9 5.9 16.6 19.0 8.5 29.1 16.4 14.5 42.9 22.1 15.3 17.8 3.2 14.5 13.7 44.1 23.7 26.1 19.4 16.2 4.6 13.0 15.6 14.4 16.9 8.8 10.4 6.9 PTS PTPS ENSG00000150787 "6-pyruvoyltetrahydropterin synthase" Q03393 11 112226365-112269955 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Disease mutation, Phenylketonuria" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001481 Uncertain Approved Cytosol Cytosol "HPA001481: AB_1079716" "unprognostic (2.08e-2)" "unprognostic (1.91e-1)" "unprognostic (9.66e-3)" "unprognostic (8.38e-3)" "unprognostic (4.58e-1)" "unprognostic (3.28e-3)" "unprognostic (2.38e-2)" "unprognostic (1.81e-2)" "unprognostic (2.05e-2)" "unprognostic (8.74e-2)" "unprognostic (2.59e-1)" "unprognostic (7.07e-2)" "unprognostic (3.81e-2)" "unprognostic (1.20e-2)" "unprognostic (2.97e-1)" "unprognostic (1.52e-3)" "unprognostic (1.65e-1)" 6.7 37.1 13.9 6.3 16.6 12.2 13.9 8.9 16.5 10.4 12.7 10.2 6.1 10.7 9.3 20.3 17.9 8.2 14.7 11.6 11.8 28.9 21.9 40.7 5.6 10.4 23.5 14.3 6.7 11.9 12.1 21.5 12.1 18.8 14.9 14.4 9.9 10.9 11.4 11.7 11.5 10.9 12.4 16.8 5.1 18.8 6.7 9.8 3.6 16.3 13.2 7.7 9.3 16.1 6.3 6.8 1.9 5.5 3.4 5.9 2.9 10.7 11.3 12.4 5.3 8.9 10.6 16.4 32.0 14.6 17.6 18.7 25.5 10.8 11.4 24.5 18.8 15.6 17.5 20.6 19.0 9.3 14.7 2.9 17.5 20.9 28.1 7.0 1.6 18.4 29.2 16.8 19.9 13.1 11.0 6.2 11.0 11.8 5.4 9.2 9.2 22.4 3.6 2.4 16.4 37.8 15.4 14.0 14.1 18.0 17.6 10.0 13.2 6.3 16.6 17.3 18.9 20.6 25.2 4.3 8.6 27.4 12.0 7.5 18.0 0.9 2.1 1.9 3.8 2.3 3.8 5.5 5.0 4.7 3.6 6.3 3.5 4.5 1.0 3.4 5.5 6.8 5.9 2.9 13.9 16.6 8.9 16.5 11.8 28.9 23.5 14.3 18.8 9.8 PUDP "DXF68S1E, FAM16AX, GS1, HDHD1, HDHD1A" ENSG00000130021 "Pseudouridine 5'-phosphatase" Q08623 X 7048920-7148190 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" HPA072672 Approved 14000 "HPA072672: " "unprognostic (1.84e-1)" "unprognostic (4.93e-2)" "unprognostic (5.15e-3)" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (5.63e-3)" "unprognostic (1.00e-3)" "unprognostic (3.22e-2)" "unprognostic (4.86e-2)" "unprognostic (4.85e-2)" "prognostic unfavourable (7.27e-4)" "unprognostic (2.24e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-1)" "unprognostic (2.92e-2)" "prognostic favourable (4.80e-4)" "unprognostic (3.42e-2)" 10.8 9.3 10.2 10.3 12.5 2.6 7.5 7.8 10.5 9.1 15.0 9.7 9.1 15.2 8.6 6.3 9.9 17.0 7.1 17.1 8.1 10.6 19.8 10.1 10.3 13.1 12.5 7.1 9.6 8.9 7.3 11.2 42.4 10.0 7.4 10.5 8.3 9.8 6.9 31.8 5.0 15.1 9.8 10.6 11.2 15.8 7.7 11.4 13.3 10.4 8.9 13.1 10.2 8.9 7.0 11.1 2.1 14.9 5.1 9.6 7.5 19.9 18.8 29.8 12.4 15.2 15.0 5.1 7.1 6.9 7.9 8.1 26.7 12.3 9.2 14.8 7.1 6.1 13.5 16.0 12.3 8.2 26.0 9.7 7.1 14.6 7.2 8.5 11.0 7.8 6.2 21.5 10.0 23.6 18.6 8.4 12.5 9.3 9.5 12.6 15.7 9.3 7.1 11.5 24.9 11.4 7.5 7.1 7.5 5.7 10.6 10.6 11.8 8.0 9.1 4.9 3.0 20.4 6.0 26.8 0.1 15.0 7.0 4.9 9.5 2.1 14.4 1.6 6.4 14.9 6.4 7.0 6.8 6.0 11.1 5.2 5.2 5.8 1.5 5.1 14.0 3.6 9.6 7.5 10.2 12.5 7.8 10.5 8.1 10.6 12.5 7.1 10.0 11.4 PUS1 ENSG00000177192 "Pseudouridylate synthase 1" Q9Y606 12 131929200-131945896 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Isomerase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051636, HPA057593" Approved Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA051636: , HPA057593: " "unprognostic (2.72e-1)" "unprognostic (9.13e-2)" "unprognostic (1.81e-1)" "unprognostic (2.69e-2)" "unprognostic (8.12e-3)" "unprognostic (8.07e-2)" "unprognostic (4.57e-3)" "unprognostic (7.34e-2)" "unprognostic (1.01e-1)" "unprognostic (3.34e-1)" "unprognostic (2.06e-1)" "unprognostic (5.30e-2)" "prognostic unfavourable (3.49e-8)" "unprognostic (1.80e-3)" "unprognostic (8.06e-2)" "unprognostic (8.59e-2)" "unprognostic (1.56e-2)" 12.7 15.8 18.8 19.5 23.3 26.2 11.2 8.8 16.9 8.7 11.9 9.4 11.0 12.4 13.6 18.7 16.5 12.9 25.1 8.6 15.6 8.3 10.7 22.8 11.0 21.4 11.7 15.8 10.1 19.8 7.2 9.5 8.3 11.7 11.7 10.5 7.6 11.4 15.7 13.5 15.4 13.9 9.7 6.2 17.4 13.6 11.9 16.4 11.6 10.3 11.6 15.8 10.8 12.8 5.9 4.6 1.9 2.0 9.1 4.0 1.3 15.2 20.0 4.7 8.4 4.6 7.9 29.2 11.8 5.0 9.0 5.8 22.1 10.0 18.3 13.7 6.4 19.4 15.6 11.2 5.9 8.1 31.6 18.4 9.7 19.3 12.4 31.4 16.9 7.9 9.1 10.3 8.8 8.8 22.8 5.6 5.2 26.6 20.6 28.2 25.1 30.5 19.7 6.8 18.9 7.3 21.3 13.3 7.4 9.9 13.6 10.9 14.9 34.0 7.7 7.2 15.4 15.3 17.1 15.5 11.6 21.7 7.4 25.2 9.9 1.2 2.0 0.4 3.2 1.4 2.2 5.9 2.7 3.3 1.6 5.5 4.0 2.1 1.9 9.1 1.3 4.6 2.4 1.3 18.8 23.3 8.8 16.9 15.6 8.3 11.7 15.8 11.7 16.4 PUS10 "CCDC139, FLJ32312" ENSG00000162927 "Pseudouridylate synthase 10" Q3MIT2 2 60940222-61018259 "Enzymes, Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044736, HPA049582" Approved Approved "Nucleoplasm,Nuclear bodies,Mitochondria" "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA044736: AB_2679066, HPA049582: " "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (3.49e-2)" "unprognostic (2.44e-4)" "unprognostic (1.77e-1)" "unprognostic (1.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.72e-2)" "unprognostic (2.90e-2)" "unprognostic (8.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.45e-1)" "unprognostic (1.16e-4)" "unprognostic (1.07e-1)" "unprognostic (6.60e-2)" "unprognostic (9.45e-2)" "unprognostic (1.15e-3)" 7.0 8.7 7.4 5.0 7.3 3.9 7.3 6.8 7.9 4.8 10.0 5.1 3.0 9.2 7.7 9.1 5.0 5.4 6.4 4.6 6.5 6.9 8.5 17.6 6.3 6.5 8.5 4.6 6.8 7.2 6.3 10.3 4.2 5.9 6.6 6.0 6.7 6.2 3.9 6.7 4.3 19.8 3.6 7.1 5.9 4.2 7.8 8.0 9.1 10.4 4.1 8.3 4.4 4.4 5.2 4.9 9.8 6.9 4.8 4.3 1.8 2.7 1.6 4.4 7.6 3.9 4.3 5.2 5.6 5.2 5.5 5.2 4.2 3.9 8.7 5.8 3.1 3.0 5.1 4.5 6.7 8.8 2.5 7.9 2.1 13.3 7.1 8.7 5.0 5.2 5.4 3.9 9.4 6.9 8.0 6.1 3.8 2.5 6.9 7.0 4.0 3.0 6.7 5.9 4.4 3.2 5.2 2.6 3.6 4.5 8.0 9.0 3.1 5.5 5.3 5.4 4.2 3.5 4.0 7.3 3.2 18.4 4.6 5.1 6.0 9.8 1.9 2.0 3.9 2.2 4.3 5.2 2.5 2.6 1.6 3.2 3.0 3.4 4.1 4.8 6.9 4.9 1.5 1.8 7.4 7.3 6.8 7.9 6.5 6.9 8.5 4.6 5.9 8.0 PUS3 FKSG32 ENSG00000110060 "Pseudouridylate synthase 3" Q9BZE2 11 125893485-125903221 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Isomerase "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038040, HPA063802" Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA038040: AB_10697092, HPA063802: " "unprognostic (5.89e-2)" "unprognostic (7.24e-2)" "unprognostic (1.29e-1)" "unprognostic (4.37e-3)" "unprognostic (4.59e-2)" "prognostic unfavourable (8.10e-4)" "unprognostic (7.67e-2)" "unprognostic (1.77e-1)" "unprognostic (8.92e-3)" "unprognostic (4.47e-3)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-3)" "unprognostic (9.95e-2)" "unprognostic (1.32e-1)" "unprognostic (1.13e-1)" "unprognostic (2.44e-1)" 8.6 8.8 5.9 7.4 7.7 2.3 8.7 9.0 8.4 7.4 9.2 3.6 4.6 9.9 8.4 8.6 8.1 6.4 5.9 7.6 8.0 6.4 9.6 36.6 6.1 11.0 8.7 7.2 7.7 17.9 8.2 21.1 7.6 7.7 10.4 7.4 5.4 10.6 5.1 15.2 8.2 11.5 13.9 9.7 8.9 9.3 5.3 7.3 9.6 12.4 10.6 9.2 11.1 7.3 13.0 8.8 9.9 12.3 13.0 16.5 7.1 3.5 4.3 13.3 14.9 13.7 17.5 6.4 11.9 10.0 6.8 7.6 14.1 13.4 18.1 19.6 5.2 12.4 21.6 11.0 6.9 15.4 10.4 18.6 5.5 10.1 14.5 11.7 5.5 13.8 13.3 8.1 17.4 12.5 18.9 9.5 7.3 2.1 13.0 12.5 11.5 8.5 2.6 12.2 10.2 11.2 5.6 15.5 13.8 8.1 11.4 6.5 24.3 7.6 8.4 14.4 5.9 6.8 9.8 7.1 10.6 19.1 3.9 18.8 9.8 9.9 9.7 7.8 13.0 9.4 15.2 13.0 12.8 12.5 8.8 12.2 16.5 15.6 3.7 13.0 12.3 7.8 12.9 7.1 5.9 7.7 9.0 8.4 8.0 6.4 8.7 7.2 7.7 7.3 PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 60.8" "Cell line enhanced" "Detected in many" "EFO-21: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 2.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA012375 Approved "Secreted to extracellular matrix" 4000000 "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavourable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavourable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavourable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" 36.4 3.2 2.6 13.1 2.0 0.5 60.8 0.3 3.7 15.5 17.7 2.7 5.1 4.3 20.4 8.9 7.4 9.7 12.9 16.2 2.0 2.6 5.8 6.9 14.3 8.5 1.8 1.4 19.2 2.1 1.5 6.5 18.3 3.6 15.2 5.0 7.6 7.3 6.8 8.4 3.7 8.4 41.0 2.6 13.7 7.8 5.8 1.2 4.3 5.9 4.8 3.4 26.3 20.1 0.5 2.0 0.0 0.0 0.0 1.1 0.1 6.7 2.4 12.7 0.0 36.0 33.1 9.7 40.2 32.0 17.6 19.3 0.0 0.1 0.0 57.8 39.7 1.4 0.0 24.7 22.5 0.1 0.4 0.0 25.2 0.0 35.8 0.1 0.0 36.4 7.3 19.9 15.0 43.3 0.0 0.0 25.0 4.0 1.1 1.3 10.3 9.2 2.2 44.5 0.1 20.7 0.0 0.0 23.5 0.0 13.0 0.0 4.7 0.1 42.0 29.2 14.4 1.1 31.0 0.0 33.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.5 0.0 0.0 0.0 0.0 1.1 0.5 0.0 0.0 0.0 2.0 0.0 0.1 2.6 2.0 0.3 2.7 2.0 2.6 1.8 1.4 3.6 1.2 PXDNL "FLJ25471, PMR1" ENSG00000147485 "Peroxidasin like" A1KZ92 8 51319578-51809445 "Enzymes, Predicted intracellular proteins" "Hydrogen peroxide" "Endonuclease, Hydrolase, Nuclease, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "heart muscle: 59.1" "Group enriched" "Detected in some" 7 "AF22: 10.8;Daudi: 8.1;SH-SY5Y: 8.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" HPA007919 Approved Nucleoplasm,Cytosol "Intracellular and membrane" "Nucleoplasm, Cytosol" "HPA007919: AB_1855966" "prognostic unfavourable (3.27e-5)" "unprognostic (4.59e-4)" "unprognostic (5.57e-3)" "unprognostic (2.83e-3)" "unprognostic (2.71e-1)" "unprognostic (5.14e-2)" "unprognostic (1.18e-1)" "unprognostic (7.18e-3)" "unprognostic (1.85e-1)" "unprognostic (1.15e-1)" "unprognostic (7.07e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-4)" "unprognostic (2.28e-2)" "unprognostic (3.35e-2)" "unprognostic (2.42e-2)" "unprognostic (2.97e-4)" 1.1 0.1 0.3 0.1 0.2 0.0 0.2 0.1 0.9 0.1 0.1 0.0 0.2 0.0 0.3 7.9 0.4 0.1 0.7 59.1 0.2 0.3 1.0 0.1 0.2 0.3 0.3 0.3 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.0 1.8 1.1 0.3 0.9 0.2 0.2 0.1 0.2 0.3 0.1 5.2 0.0 0.1 0.2 2.5 0.3 0.2 0.1 1.5 0.3 0.3 0.0 0.0 0.1 0.0 0.6 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.3 0.1 0.0 0.3 0.2 0.1 0.9 0.2 0.3 0.3 0.3 0.3 0.0 PXK "FLJ20335, Slob" ENSG00000168297 "PX domain containing serine/threonine kinase like" Q7Z7A4 3 58332880-58426126 "Enzymes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 81.1" "Cell line enhanced" "Detected in many" "U-937: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024068 Approved Supported "Plasma membrane,Centriolar satellite,Cytosol" "Plasma membrane, Cytosol" "Centriolar satellite" "HPA024068: AB_1855967" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.61e-1)" "unprognostic (2.40e-1)" "unprognostic (6.62e-3)" "unprognostic (5.03e-3)" "prognostic favourable (5.68e-4)" "unprognostic (3.90e-1)" "unprognostic (8.09e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" 9.3 9.4 20.7 17.0 51.4 33.6 7.6 22.6 31.4 28.9 8.9 81.1 2.4 6.3 14.2 5.3 6.6 8.0 9.6 7.5 33.7 19.9 10.4 5.7 8.2 23.8 68.6 23.4 11.1 8.5 13.7 6.1 17.5 43.9 6.0 6.4 4.4 8.8 7.7 7.6 7.5 7.7 11.8 55.9 13.5 8.3 6.7 56.6 3.7 40.3 2.5 26.1 9.8 13.1 31.3 18.8 31.8 22.5 8.7 11.2 13.4 4.2 2.5 1.9 3.5 26.6 23.6 5.6 6.9 14.6 6.6 9.3 1.2 0.9 22.6 1.6 11.6 1.3 6.0 4.3 7.0 5.6 3.8 3.9 3.0 1.7 31.0 33.5 6.9 20.2 10.5 8.3 14.4 5.8 4.7 7.4 11.8 1.6 7.3 34.6 2.3 6.3 12.6 3.3 4.0 4.2 2.4 1.7 1.2 4.7 3.3 5.4 11.4 34.7 5.9 8.3 3.4 15.7 7.2 5.8 5.7 22.5 12.0 47.6 3.4 14.6 20.1 29.4 11.2 16.2 9.9 29.0 8.1 9.4 18.8 31.3 7.1 8.4 31.8 8.7 22.5 13.5 8.7 13.4 20.7 51.4 22.6 31.4 33.7 19.9 68.6 23.4 43.9 56.6 PYCR1 P5C ENSG00000183010 "Pyrroline-5-carboxylate reductase 1" P32322 17 81932384-81942412 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis, Stress response" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "pancreas: 56.1;salivary gland: 53.3;stomach 1: 16.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "memory B-cell: 7.7" "Group enriched" "Detected in many" 7 "B-cells: 7.7;dendritic cells: 3.3;T-cells: 3.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA047660 Approved "HPA047660: AB_2680115" "unprognostic (1.12e-2)" "unprognostic (2.13e-2)" "unprognostic (7.04e-2)" "unprognostic (7.27e-2)" "unprognostic (9.86e-2)" "unprognostic (1.60e-1)" "prognostic unfavourable (2.33e-4)" "unprognostic (2.80e-1)" "unprognostic (9.36e-3)" "unprognostic (6.65e-2)" "unprognostic (3.02e-3)" "unprognostic (7.12e-2)" "prognostic unfavourable (7.33e-12)" "unprognostic (7.98e-2)" "unprognostic (1.56e-1)" "unprognostic (1.12e-2)" "unprognostic (5.92e-2)" 2.1 1.3 4.3 5.0 5.0 4.0 6.9 2.1 4.3 10.4 9.1 2.3 10.1 5.6 4.2 2.2 6.4 3.5 5.7 3.5 3.5 3.6 2.4 3.1 4.9 2.3 6.0 2.0 7.6 56.1 0.0 7.6 8.3 6.4 10.4 5.6 1.5 53.3 4.7 3.4 1.8 4.8 4.6 2.9 2.4 16.6 8.7 4.0 1.7 3.3 4.5 6.4 4.9 4.0 7.7 3.3 0.0 0.4 0.6 3.0 2.2 19.1 20.5 11.7 43.3 7.0 13.3 22.4 32.2 15.9 10.4 14.0 23.4 21.6 29.4 7.2 34.4 8.4 27.5 12.2 6.2 7.6 3.4 17.3 10.6 63.2 41.5 11.5 13.4 11.3 24.5 12.7 33.6 17.6 55.7 27.4 6.5 67.9 12.1 9.2 9.8 31.9 0.1 19.7 37.1 9.3 7.0 45.0 31.7 6.7 38.0 41.0 39.1 21.3 12.9 10.1 38.9 17.0 11.9 34.6 24.0 27.3 10.8 0.1 33.2 0.0 0.3 0.0 0.5 0.4 0.7 7.7 1.3 0.4 2.3 3.5 3.0 2.3 0.0 0.6 0.0 3.3 0.5 2.2 4.3 5.0 2.1 3.6 3.5 3.6 6.0 2.0 6.4 4.0 PYCR2 P5CR2 ENSG00000143811 "Pyrroline-5-carboxylate reductase 2" Q96C36 1 225919877-225924340 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA056873 Approved Approved Mitochondria Mitochondria "HPA056873: " "unprognostic (1.11e-1)" "unprognostic (8.08e-2)" "prognostic unfavourable (5.02e-5)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (4.20e-3)" "unprognostic (1.56e-2)" "unprognostic (6.89e-2)" "unprognostic (1.12e-1)" "unprognostic (9.07e-3)" "unprognostic (1.56e-1)" "prognostic unfavourable (1.42e-6)" "unprognostic (9.69e-2)" "unprognostic (2.61e-1)" "unprognostic (6.44e-2)" "unprognostic (1.16e-3)" 21.4 37.2 25.7 24.0 28.2 29.5 17.2 14.3 38.2 21.8 17.4 40.0 25.8 16.1 25.3 20.0 17.7 33.2 24.6 38.0 27.9 28.3 23.4 35.0 22.0 30.3 34.0 30.8 34.5 29.0 26.6 29.8 22.2 29.5 22.4 13.7 21.5 26.3 32.1 36.0 15.3 16.7 22.3 38.4 25.9 20.1 17.6 24.7 35.0 19.2 20.0 23.5 24.6 16.2 19.3 25.9 16.4 12.7 28.3 36.1 18.1 16.7 13.8 8.5 14.2 9.6 10.0 17.9 17.7 11.1 12.1 10.8 18.1 14.0 29.5 38.1 13.0 19.4 12.1 13.9 6.9 35.4 25.4 28.1 14.4 18.1 14.9 24.7 46.3 9.6 17.6 13.6 15.8 11.5 40.6 19.8 12.2 13.8 31.0 28.1 47.3 19.3 27.9 19.0 61.1 15.6 13.4 10.7 13.8 14.8 11.8 37.0 15.1 47.3 9.6 9.5 11.4 20.1 24.3 31.7 34.7 29.2 15.0 18.9 26.2 15.1 8.7 16.4 21.1 12.7 22.2 15.9 20.6 19.5 13.6 19.3 36.1 29.2 6.0 28.3 10.8 25.9 18.6 18.1 25.7 28.2 14.3 38.2 27.9 28.3 34.0 30.8 29.5 24.7 PYCR3 "FLJ13852, PYCRL" ENSG00000104524 "Pyrroline-5-carboxylate reductase 3" Q53H96 8 143603913-143609773 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063416, HPA069706" Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA063416: , HPA069706: " "unprognostic (2.12e-2)" "unprognostic (3.16e-2)" "unprognostic (2.74e-1)" "unprognostic (2.44e-1)" "unprognostic (1.06e-2)" "unprognostic (2.30e-1)" "unprognostic (7.68e-3)" "unprognostic (1.79e-1)" "unprognostic (1.96e-1)" "unprognostic (2.26e-2)" "unprognostic (5.85e-2)" "unprognostic (5.44e-2)" "unprognostic (1.82e-2)" "unprognostic (3.64e-2)" "unprognostic (2.96e-1)" "unprognostic (3.54e-2)" "unprognostic (2.54e-1)" 6.1 8.1 11.5 6.7 9.7 4.8 5.6 5.3 13.4 6.9 5.4 6.1 10.8 4.4 4.7 5.2 6.1 10.1 6.3 4.4 12.2 8.5 7.7 20.5 5.9 6.7 7.6 12.1 6.7 10.6 4.3 9.1 3.5 9.7 7.5 4.0 4.5 13.7 9.1 4.8 4.7 4.9 4.0 4.4 5.9 7.0 8.6 4.5 3.8 9.5 6.3 6.1 3.6 3.1 11.1 5.4 0.4 1.4 3.2 3.2 2.1 5.8 11.0 2.0 4.2 1.9 1.2 4.1 5.2 2.2 4.2 2.4 4.8 5.8 7.7 7.0 3.7 4.9 1.9 6.1 0.8 5.2 6.7 3.8 4.2 3.2 1.9 1.7 1.1 2.1 1.6 4.8 2.7 2.4 5.9 2.4 2.0 18.0 7.3 1.3 1.8 17.7 5.1 1.9 11.5 3.9 3.8 7.1 2.4 8.4 10.8 1.9 13.3 2.2 2.1 3.8 7.9 5.9 4.9 4.2 1.0 4.8 4.4 2.4 3.5 0.3 1.4 0.2 3.2 1.1 3.1 5.8 2.1 2.6 2.1 11.1 3.0 3.0 0.4 3.2 1.0 5.4 1.8 2.1 11.5 9.7 5.3 13.4 12.2 8.5 7.6 12.1 9.7 4.5 PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248069-25298014 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 101.9" "Cell line enhanced" "Detected in all" "PC-3: 70.3;SK-MEL-30: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031067 Approved Approved Cytosol 16000000 Cytosol "HPA031067: " "unprognostic (6.13e-2)" "unprognostic (5.98e-2)" "unprognostic (1.21e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "prognostic unfavourable (4.37e-4)" "prognostic unfavourable (1.10e-4)" "unprognostic (1.23e-3)" "unprognostic (8.39e-3)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.22e-2)" "unprognostic (3.41e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.43e-4)" 19.0 11.3 24.2 12.1 22.9 6.1 28.4 38.3 34.8 14.3 47.0 21.5 19.0 12.5 15.9 13.8 49.6 14.1 21.1 72.5 21.1 21.3 13.5 4.4 14.8 8.1 22.9 24.7 11.9 9.7 8.0 18.2 6.2 28.0 42.2 33.8 11.0 58.4 52.0 5.0 23.9 13.1 101.9 17.8 8.2 24.1 14.5 17.4 9.5 21.1 8.4 10.3 56.7 14.8 4.5 11.2 5.2 16.8 8.1 10.6 16.0 5.2 37.6 6.8 6.6 17.4 32.8 5.0 10.6 13.9 8.9 7.5 8.4 6.5 6.2 12.5 14.1 21.1 7.6 28.2 4.9 3.5 4.7 5.0 3.1 14.4 20.6 7.3 7.0 19.0 26.5 22.7 33.6 11.4 2.7 15.8 12.5 14.5 7.3 5.7 6.1 70.3 5.6 12.3 8.2 48.9 9.6 10.2 6.3 7.2 12.8 88.2 8.9 4.7 25.0 10.6 6.4 11.3 21.5 6.1 9.5 2.4 11.9 5.8 57.6 2.6 10.2 5.2 8.5 15.5 8.3 4.5 6.8 7.5 11.2 4.2 8.8 10.6 2.5 8.1 16.8 5.5 7.5 16.0 24.2 22.9 38.3 34.8 21.1 21.3 22.9 24.7 28.0 17.4 PYGL ENSG00000100504 "Glycogen phosphorylase L" P06737 14 50857891-50944736 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 56.1;HMC-1: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 36.0;neutrophil: 41.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000962, HPA004119" Enhanced Supported "Plasma membrane,Cytosol" 17000000 "Plasma membrane, Cytosol" "HPA000962: AB_1079722, HPA004119: AB_1079723" "unprognostic (2.70e-2)" "unprognostic (8.64e-3)" "unprognostic (1.46e-2)" "unprognostic (8.55e-2)" "unprognostic (9.41e-2)" "prognostic unfavourable (5.97e-4)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (3.34e-1)" "unprognostic (1.94e-2)" "prognostic unfavourable (2.63e-4)" "unprognostic (4.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.95e-2)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-3)" 47.6 9.9 4.9 9.7 6.8 40.0 28.1 1.3 3.9 17.2 10.1 3.0 23.7 1.7 10.9 7.3 24.8 7.8 5.5 15.0 3.9 3.4 6.8 58.8 19.6 25.6 6.5 1.6 15.4 4.1 12.5 3.7 23.3 5.3 11.4 10.3 17.8 11.8 55.2 7.1 15.3 3.5 11.2 8.7 38.8 4.5 6.8 5.4 2.4 7.1 9.1 7.3 18.4 24.3 0.0 7.3 41.4 13.8 0.1 0.0 5.5 28.3 8.0 2.1 13.2 9.8 11.8 23.0 5.7 4.8 15.7 24.0 21.1 3.6 0.0 11.1 33.8 56.1 21.4 28.8 27.3 0.1 9.0 5.4 12.8 16.4 17.6 20.6 62.0 25.1 11.8 21.3 9.0 13.9 2.2 0.1 11.1 28.3 0.0 28.4 7.9 29.7 0.5 7.3 1.1 21.8 19.0 0.9 0.9 25.8 9.0 0.3 4.2 40.4 0.6 6.1 10.2 11.4 18.3 0.2 0.0 0.0 5.6 21.3 3.2 11.3 13.8 36.0 0.0 6.3 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 41.4 0.1 3.9 0.3 0.0 5.5 4.9 6.8 1.3 3.9 3.9 3.4 6.5 1.6 5.3 5.4 PYGM ENSG00000068976 "Glycogen phosphorylase, muscle associated" P11217 11 64746389-64760297 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 37 "skeletal muscle: 572.6;tongue: 172.6" "Cell line enhanced" "Detected in some" "HSkMC: 8.2;NB-4: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 9.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056003 Enhanced 12000000 "HPA056003: " "unprognostic (3.33e-1)" "unprognostic (6.03e-3)" "unprognostic (3.87e-4)" "unprognostic (1.95e-3)" "unprognostic (8.71e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (2.92e-1)" "unprognostic (3.88e-1)" "unprognostic (3.08e-2)" "unprognostic (1.12e-1)" "unprognostic (2.64e-1)" "unprognostic (6.33e-6)" "unprognostic (3.37e-3)" "unprognostic (1.81e-1)" "unprognostic (1.62e-2)" "unprognostic (5.68e-2)" 6.4 0.8 2.2 0.7 3.0 0.7 0.8 1.1 3.1 0.9 2.1 1.8 0.7 0.7 1.1 4.6 7.1 1.5 0.9 5.5 2.9 1.0 0.7 0.6 0.7 0.7 1.5 1.1 0.7 0.7 0.6 0.3 0.7 6.6 2.5 0.9 1.6 7.9 2.8 572.6 0.6 0.8 2.5 4.1 0.7 0.8 0.9 1.8 0.0 1.2 172.6 6.4 1.5 0.6 1.9 0.3 9.9 0.0 1.6 0.3 0.2 0.2 0.1 1.7 0.2 1.2 1.7 0.3 0.2 0.1 0.3 0.0 0.7 0.7 1.3 0.5 0.0 0.3 0.5 0.1 0.1 1.4 0.3 0.8 0.3 0.0 0.7 0.8 0.3 8.2 0.6 0.6 0.2 0.0 1.5 1.5 0.0 2.1 1.4 4.7 1.7 0.2 0.9 1.5 0.3 0.0 0.2 0.5 0.1 0.6 0.7 0.9 0.7 0.9 0.6 0.0 0.9 0.3 0.1 2.3 2.8 1.0 0.0 0.2 0.0 9.9 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.2 0.0 1.9 0.0 0.1 0.2 1.6 0.0 0.3 0.3 0.2 2.2 3.0 1.1 3.1 2.9 1.0 1.5 1.1 6.6 1.8 QARS ENSG00000172053 "Glutaminyl-tRNA synthetase" P47897 3 49095932-49105135 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Epilepsy, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036986, HPA036987" Enhanced Enhanced Cytosol 21000 Cytosol "HPA036986: AB_10672344, HPA036987: AB_2675418" "prognostic favourable (1.43e-4)" "unprognostic (1.96e-1)" "unprognostic (7.31e-2)" "unprognostic (1.10e-2)" "unprognostic (5.13e-3)" "unprognostic (6.62e-3)" "unprognostic (6.53e-3)" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (2.51e-1)" "unprognostic (4.33e-1)" "unprognostic (9.14e-2)" "prognostic favourable (5.60e-6)" "unprognostic (2.73e-3)" "unprognostic (1.65e-1)" "unprognostic (2.74e-2)" "unprognostic (3.11e-1)" 20.9 16.3 9.7 19.3 10.2 18.4 22.7 15.8 13.2 17.6 27.3 13.1 27.7 17.2 12.3 19.8 35.1 16.4 20.0 22.0 9.8 9.6 27.1 26.0 15.0 33.9 12.4 7.2 21.6 33.8 20.3 13.7 25.7 9.6 16.2 29.9 15.2 31.7 28.7 33.3 26.7 31.8 16.7 11.2 21.1 16.9 30.1 11.3 36.8 16.5 34.8 33.3 19.4 18.5 20.4 40.0 8.9 32.3 21.8 24.0 19.6 18.6 19.0 31.6 45.3 40.8 44.4 32.6 20.7 47.4 41.2 40.5 23.9 24.2 57.6 13.3 34.3 23.7 44.9 34.1 29.6 16.4 35.9 45.4 30.4 41.8 21.5 36.9 28.0 46.7 29.9 31.7 27.0 44.9 20.2 25.6 30.1 10.0 26.6 33.1 27.2 29.6 17.5 26.6 42.5 27.6 27.8 11.6 32.4 18.4 46.7 28.6 38.7 43.1 25.9 18.8 26.6 30.9 23.1 22.1 37.6 32.3 19.2 33.3 11.9 8.9 23.1 8.7 13.5 32.3 18.1 20.4 16.8 14.9 40.0 15.2 15.5 15.4 2.6 21.8 26.1 16.9 24.0 19.6 9.7 10.2 15.8 13.2 9.8 9.6 12.4 7.2 9.6 11.3 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512234 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease mutation, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 114.1;liver: 64.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria 1800000 Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favourable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 22.5 25.9 67.8 3.4 111.9 4.4 7.4 16.0 54.1 5.7 7.5 56.3 2.6 9.1 5.5 12.5 5.2 6.4 6.3 15.0 80.7 58.2 36.1 64.8 8.0 3.7 114.1 36.7 6.7 10.3 13.7 6.2 4.1 82.5 10.3 5.9 2.6 12.4 7.5 34.2 4.6 8.1 6.4 93.6 4.8 9.1 4.1 94.7 0.7 7.7 2.8 4.4 4.5 2.6 7.5 42.5 1.0 21.9 9.9 15.0 12.3 11.3 22.3 8.8 12.3 21.4 10.9 15.6 16.3 6.9 15.2 13.4 17.8 15.1 4.2 10.5 9.0 6.5 12.5 18.4 9.5 12.9 2.5 11.5 11.6 42.1 12.9 15.0 1.0 13.5 11.7 9.6 13.1 7.6 12.4 9.7 16.3 5.9 22.3 24.1 15.0 15.1 9.3 6.8 16.9 15.7 6.3 16.7 21.4 10.8 1.8 46.3 4.9 5.8 13.2 8.8 15.8 8.7 12.9 15.1 23.5 29.6 17.6 13.3 14.6 0.0 14.4 1.0 12.3 21.9 11.1 7.5 13.3 12.8 18.0 6.2 15.0 12.9 0.4 9.9 16.3 42.5 6.9 12.3 67.8 111.9 16.0 54.1 80.7 58.2 114.1 36.7 82.5 94.7 QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37344574-37373322 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 77.6;blood: 137.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.5;SCLC-21H: 23.8;SK-MEL-30: 80.0;U-266/84: 62.5" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "neutrophil: 137.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 137.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" 3.2 77.6 4.3 5.4 5.8 17.0 6.4 1.2 11.6 9.2 11.3 2.2 1.5 2.2 6.2 43.7 2.4 1.9 5.5 2.9 6.7 17.9 12.4 1.3 6.1 7.4 3.9 5.0 1.4 5.5 9.6 31.6 7.8 5.9 3.5 4.2 21.2 14.7 2.8 4.0 14.2 2.3 3.4 3.0 8.5 3.4 2.6 0.5 2.3 1.8 4.4 4.8 7.0 2.9 0.2 10.7 137.6 29.7 0.0 0.0 12.1 0.1 7.9 0.0 0.0 1.0 2.6 0.0 1.0 17.5 1.3 2.1 0.5 1.4 0.0 0.6 5.9 0.0 0.5 0.0 2.1 0.1 15.3 3.5 0.0 1.5 0.1 0.5 0.0 1.5 0.0 9.7 0.0 5.2 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.0 0.0 0.1 8.6 2.1 23.8 0.0 1.3 0.0 80.0 0.1 0.5 3.7 0.0 0.0 0.0 0.1 3.0 62.5 0.0 5.3 0.0 0.0 0.6 29.7 0.2 0.0 3.4 0.0 0.2 0.0 0.0 10.7 0.1 0.0 0.0 137.6 0.0 0.3 0.2 0.0 12.1 4.3 5.8 1.2 11.6 6.7 17.9 3.9 5.0 5.9 0.5 QPCTL FLJ20084 ENSG00000011478 "Glutaminyl-peptide cyclotransferase like" Q9NXS2 19 45692483-45703989 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040797 Approved Supported "Golgi apparatus" "Golgi apparatus" "HPA040797: AB_10794148" "unprognostic (6.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.09e-1)" "unprognostic (7.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.26e-1)" "unprognostic (8.41e-3)" "unprognostic (2.30e-2)" "unprognostic (9.46e-2)" "unprognostic (1.69e-1)" "unprognostic (3.14e-2)" "unprognostic (6.05e-2)" "prognostic unfavourable (2.15e-8)" "unprognostic (1.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.02e-2)" "unprognostic (5.71e-2)" 6.3 10.2 8.2 9.6 10.2 13.3 7.8 10.3 13.5 9.6 11.6 6.3 9.6 11.2 7.6 10.2 11.4 8.6 15.9 5.0 8.9 10.8 7.9 18.2 11.8 10.7 7.3 8.0 11.2 10.7 9.5 10.8 9.6 10.8 10.8 9.5 7.7 13.5 10.8 3.2 12.4 7.9 6.1 6.4 12.9 9.5 5.9 5.0 9.7 17.1 7.5 13.2 11.9 6.4 3.1 3.6 5.1 2.1 4.1 4.3 1.2 10.1 6.9 5.5 22.6 5.5 2.6 4.2 6.6 9.5 9.4 15.5 7.3 7.6 12.4 7.2 7.2 6.4 6.8 7.3 5.8 3.5 8.7 4.6 8.9 14.5 9.3 4.6 8.0 4.8 8.9 7.8 11.4 8.3 6.1 21.8 5.8 8.0 4.3 5.5 3.9 3.9 5.1 4.0 9.9 10.7 4.8 5.2 3.2 6.7 5.5 11.2 4.2 7.2 5.3 4.8 8.0 5.0 6.3 20.4 12.1 11.7 16.6 10.6 3.8 3.1 2.0 0.9 4.3 2.1 3.0 3.1 2.1 1.4 2.4 2.8 2.1 2.8 5.1 4.1 1.3 3.6 1.4 1.2 8.2 10.2 10.3 13.5 8.9 10.8 7.3 8.0 10.8 5.0 QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29679008-29698699 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.2" "Cell line enhanced" "Detected in many" "EFO-21: 96.7;Hep G2: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 7.7" "Group enriched" "Detected in many" 4 "dendritic cells: 4.6;monocytes: 7.7" HPA011887 Approved "Intracellular and membrane" 230000 "HPA011887: AB_2668555" "prognostic unfavourable (5.10e-5)" "unprognostic (2.00e-1)" "unprognostic (9.48e-2)" "unprognostic (2.88e-1)" "prognostic unfavourable (9.31e-4)" "unprognostic (1.44e-2)" "unprognostic (8.75e-2)" "unprognostic (1.22e-1)" "unprognostic (8.16e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (6.81e-2)" "unprognostic (3.37e-2)" "unprognostic (1.33e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-2)" 3.2 36.4 6.1 3.0 5.2 1.1 2.4 1.6 5.8 17.9 10.8 4.4 43.3 20.0 12.7 44.3 1.3 14.9 4.9 11.3 4.9 7.5 40.1 61.2 4.7 2.9 7.9 7.5 15.3 22.9 6.1 2.6 24.3 10.0 4.4 5.2 12.6 15.0 19.4 1.5 1.6 24.1 4.7 6.4 5.3 2.7 3.1 2.6 3.7 2.2 0.3 2.1 5.9 5.1 0.1 4.6 1.2 7.7 0.5 1.4 2.2 0.1 0.2 9.2 10.1 1.5 3.8 22.6 0.9 0.9 1.5 1.8 23.1 16.5 0.4 96.7 1.8 0.1 3.1 0.1 0.8 0.1 2.1 4.7 0.3 40.3 8.8 0.6 1.9 12.0 0.2 0.8 0.0 0.0 11.8 0.5 0.0 22.5 3.0 16.4 28.1 0.0 13.0 2.8 9.1 8.4 0.7 7.4 15.1 0.0 26.3 19.3 19.6 21.1 0.1 0.4 3.8 0.1 0.0 0.3 0.7 3.0 0.7 1.7 1.5 0.0 3.7 0.4 1.3 4.7 1.4 0.1 0.9 1.0 4.6 0.1 0.1 0.7 1.2 0.5 7.7 2.6 0.8 2.2 6.1 5.2 1.6 5.8 4.9 7.5 7.9 7.5 10.0 2.6 QRSL1 "DKFZP564C1278, FLJ10989, FLJ12189, FLJ13447, GatA" ENSG00000130348 "Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1" Q9H0R6 6 106629578-106668417 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "memory B-cell: 32.6;naive B-cell: 26.1" "Lineage enriched" "Detected in all" 7 "B-cells: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029585, HPA029587" Approved Approved Vesicles,Centrosome Vesicles Centrosome "HPA029585: AB_10599823, HPA029587: AB_10602311" "unprognostic (1.86e-3)" "unprognostic (5.58e-2)" "unprognostic (6.19e-3)" "unprognostic (3.45e-1)" "unprognostic (2.11e-3)" "unprognostic (1.31e-2)" "prognostic unfavourable (7.97e-5)" "unprognostic (8.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (4.03e-2)" "unprognostic (1.66e-1)" "prognostic favourable (3.83e-4)" "unprognostic (2.06e-1)" "unprognostic (2.09e-1)" "unprognostic (2.04e-1)" "unprognostic (3.46e-1)" 9.8 10.8 12.4 17.0 14.7 8.5 15.6 10.1 15.6 7.6 11.7 10.1 11.9 11.3 9.5 10.8 10.3 8.5 8.3 13.9 10.4 9.1 15.5 12.5 7.7 21.0 15.8 8.3 10.2 10.8 10.9 11.9 8.7 9.9 8.3 13.7 7.5 10.6 12.5 35.7 8.8 14.8 8.8 11.9 16.7 11.0 10.6 13.7 13.8 13.7 14.6 21.3 8.9 8.6 32.6 4.0 1.6 4.5 2.6 3.1 2.2 6.1 6.4 8.8 12.7 5.7 7.2 12.4 7.0 7.2 9.4 9.4 7.4 5.1 20.5 6.4 7.8 10.9 13.1 8.5 11.9 9.7 10.0 10.0 6.8 7.6 9.0 22.5 9.0 7.0 13.3 10.0 14.8 6.6 18.0 6.7 7.7 6.9 7.2 11.0 9.2 7.5 19.7 11.3 5.2 10.2 7.1 7.7 7.9 5.6 13.1 10.3 8.6 17.5 6.5 6.7 5.5 7.1 10.8 3.9 5.5 12.0 9.1 15.3 9.9 1.6 2.4 0.4 2.6 3.6 2.5 32.6 2.9 2.2 4.0 26.1 2.7 2.6 0.7 2.6 4.5 3.2 3.1 2.2 12.4 14.7 10.1 15.6 10.4 9.1 15.8 8.3 9.9 13.7 QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154834-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 172.2" "Cell line enhanced" "Detected in many" "HHSteC: 194.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042127, HPA056243" Uncertain Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" 3200000000 "Golgi apparatus" Vesicles "HPA042127: , HPA056243: " "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavourable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" 15.9 18.7 8.0 14.5 9.5 30.1 12.6 7.3 13.6 23.5 25.3 13.8 24.9 19.8 17.8 44.9 36.8 18.9 91.9 54.4 10.1 9.0 15.4 23.1 42.3 19.5 8.5 9.1 46.5 59.8 6.2 13.5 172.2 13.4 28.0 24.5 12.1 20.6 19.4 18.4 12.3 19.0 33.9 15.5 13.4 52.8 50.3 9.1 6.7 7.8 18.2 18.3 35.8 26.1 2.9 19.2 20.4 25.5 8.0 7.1 11.4 41.5 5.9 1.4 17.7 18.1 37.5 70.5 44.2 44.7 37.8 26.7 0.6 13.4 0.6 27.5 35.3 9.0 1.7 11.9 18.5 2.4 2.7 1.3 3.5 1.8 194.6 4.5 12.8 20.0 5.4 40.3 48.4 55.6 1.8 6.5 24.9 7.2 0.9 8.4 4.8 17.0 1.8 3.2 1.0 6.2 11.9 5.1 5.2 12.9 17.6 8.5 3.2 21.5 65.4 47.4 18.6 31.7 37.3 4.8 7.8 1.1 18.0 14.6 14.2 5.8 25.5 9.5 7.1 14.7 5.3 2.9 4.8 5.0 19.2 1.8 4.4 4.3 20.4 8.0 13.1 3.9 5.5 11.4 8.0 9.5 7.3 13.6 10.1 9.0 8.5 9.1 13.4 9.1 QSOX2 "DKFZp762A2013, QSCN6L1, SOXN" ENSG00000165661 "Quiescin sulfhydryl oxidase 2" Q6ZRP7 9 136206333-136245841 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 3.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012716, HPA017280" Uncertain Enhanced "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" 5700000 "Golgi apparatus" Nucleoplasm "HPA012716: AB_2173315, HPA017280: " "unprognostic (7.29e-2)" "unprognostic (7.35e-3)" "unprognostic (6.23e-2)" "unprognostic (5.28e-2)" "unprognostic (1.49e-1)" "unprognostic (4.46e-3)" "unprognostic (1.10e-3)" "unprognostic (4.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.06e-3)" "unprognostic (5.96e-2)" "unprognostic (2.56e-2)" "prognostic unfavourable (9.64e-6)" "unprognostic (1.23e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.10e-2)" 7.2 8.0 8.4 15.9 14.1 16.0 7.3 30.3 10.6 5.8 5.8 9.4 8.9 6.0 8.1 13.2 5.6 8.1 5.5 7.0 7.6 7.1 7.0 9.2 6.5 19.1 11.0 6.7 9.4 21.7 12.1 29.2 5.8 9.6 6.1 6.7 7.9 6.5 4.9 5.1 12.4 10.3 8.1 7.1 14.6 7.6 11.7 10.1 8.3 12.1 6.0 16.7 5.4 6.4 3.4 0.8 1.6 0.3 0.4 0.8 0.2 7.2 17.7 14.7 19.5 8.3 10.1 18.6 9.3 10.4 18.1 16.7 13.2 15.8 11.2 15.3 12.4 23.6 17.4 13.4 14.7 16.5 8.7 6.0 29.3 14.5 11.8 17.8 9.2 8.0 13.6 17.9 21.8 13.2 14.4 30.3 9.6 12.3 6.6 11.9 17.4 11.3 12.2 19.1 18.3 6.2 6.6 15.8 11.9 14.6 11.6 7.8 8.3 10.4 7.5 22.0 16.0 18.0 21.1 10.7 14.3 24.7 14.7 9.4 20.5 1.6 0.3 0.7 0.5 0.0 0.8 1.9 0.6 0.2 0.1 3.4 0.2 0.4 0.1 0.4 0.0 0.8 0.3 0.2 8.4 14.1 30.3 10.6 7.6 7.1 11.0 6.7 9.6 10.1 QTRT1 TGT ENSG00000213339 "Queuine tRNA-ribosyltransferase catalytic subunit 1" Q9BXR0 19 10701430-10713437 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042695, HPA048651, HPA049440" Approved Approved Mitochondria Mitochondria "HPA042695: , HPA048651: , HPA049440: AB_2680767" "unprognostic (6.19e-2)" "prognostic favourable (7.63e-5)" "unprognostic (2.90e-2)" "unprognostic (3.05e-1)" "unprognostic (4.90e-2)" "prognostic favourable (4.90e-4)" "unprognostic (2.52e-1)" "unprognostic (8.76e-3)" "unprognostic (3.88e-1)" "unprognostic (4.81e-3)" "prognostic favourable (2.13e-4)" "unprognostic (1.14e-2)" "prognostic unfavourable (1.13e-6)" "unprognostic (2.04e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" 14.0 18.4 20.6 13.4 29.1 14.2 11.5 18.0 21.3 11.3 14.5 13.3 19.4 12.8 15.3 11.6 14.6 15.8 13.5 19.5 19.7 13.1 11.8 18.9 8.4 13.5 22.9 19.3 22.1 33.9 5.8 12.0 9.8 19.9 13.7 6.6 10.5 26.6 12.7 20.5 12.6 14.2 13.3 12.7 11.5 12.5 5.0 22.2 5.3 19.0 11.9 10.3 12.0 10.3 19.6 19.1 0.9 14.4 18.5 18.8 10.4 17.1 13.9 6.6 19.3 6.9 8.4 8.6 8.8 7.9 10.3 10.2 11.0 6.6 19.4 21.7 5.0 11.6 6.0 10.6 3.4 11.4 8.3 12.8 5.6 23.3 12.1 18.9 11.3 12.4 9.1 6.7 9.8 10.5 14.0 22.4 5.1 26.9 16.3 23.7 17.4 21.5 17.2 8.8 30.0 8.4 11.0 21.5 9.3 13.5 14.8 11.5 9.4 8.0 8.1 15.9 8.8 25.4 20.5 24.7 19.0 9.5 8.6 23.1 19.2 0.9 8.3 0.2 15.1 14.4 18.8 19.6 16.3 13.1 16.4 19.0 17.5 13.9 0.6 18.5 7.3 19.1 17.7 10.4 20.6 29.1 18.0 21.3 19.7 13.1 22.9 19.3 19.9 22.2 RABGGTA PTAR3 ENSG00000100949 "Rab geranylgeranyltransferase alpha subunit" Q92696 14 24265538-24271739 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043488 Approved Enhanced Nucleoplasm Nucleoplasm "HPA043488: AB_10794887" "unprognostic (2.00e-1)" "unprognostic (8.37e-2)" "unprognostic (2.61e-3)" "unprognostic (1.13e-1)" "unprognostic (8.34e-2)" "unprognostic (1.39e-1)" "unprognostic (2.78e-1)" "unprognostic (5.78e-2)" "unprognostic (3.89e-2)" "unprognostic (7.11e-2)" "unprognostic (3.12e-2)" "unprognostic (1.12e-1)" "prognostic favourable (5.44e-4)" "unprognostic (1.77e-1)" "unprognostic (1.84e-1)" "prognostic favourable (1.51e-4)" "unprognostic (2.01e-1)" 6.9 9.9 8.6 7.1 9.4 8.7 7.5 9.4 16.2 8.2 9.8 8.4 13.6 7.2 6.4 11.6 37.2 12.3 8.1 10.9 6.9 8.0 12.5 15.0 10.6 10.7 7.7 8.5 8.0 16.4 15.7 10.2 14.1 10.6 8.0 8.0 7.2 12.8 9.2 11.1 13.3 12.1 6.9 6.1 11.5 9.4 11.3 7.0 7.3 9.4 20.3 18.2 8.4 11.4 6.5 12.7 6.7 16.8 6.9 6.3 6.3 3.5 5.9 2.3 3.2 3.7 6.8 12.5 5.3 5.1 8.6 7.5 6.0 5.2 5.4 3.9 6.5 6.9 2.8 12.2 3.5 6.8 7.2 3.1 5.0 20.6 7.0 6.6 11.9 7.3 14.0 4.2 5.7 7.1 2.7 4.2 6.6 15.3 3.5 4.9 1.4 8.6 3.1 2.1 3.8 7.8 6.8 6.1 3.6 4.0 8.3 4.3 4.1 4.7 5.2 4.1 3.0 1.8 2.8 5.7 4.3 3.4 2.8 4.2 6.3 3.1 10.0 6.7 5.9 16.8 5.1 6.5 5.7 5.1 12.7 4.2 5.0 4.4 2.6 6.9 12.4 4.0 6.3 6.3 8.6 9.4 9.4 16.2 6.9 8.0 7.7 8.5 10.6 7.0 RABGGTB ENSG00000137955 "Rab geranylgeranyltransferase beta subunit" P53611 1 75786197-75795079 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026585, HPA027167, HPA030793" Approved Supported Approved Vesicles Vesicles "HPA026585: AB_1856026, HPA027167: AB_1856027, HPA030793: " "unprognostic (4.83e-2)" "unprognostic (3.04e-1)" "unprognostic (2.09e-2)" "unprognostic (2.45e-2)" "unprognostic (9.02e-2)" "unprognostic (3.52e-2)" "prognostic unfavourable (9.80e-5)" "unprognostic (9.62e-3)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (6.95e-2)" "prognostic unfavourable (1.12e-5)" "unprognostic (6.05e-2)" "unprognostic (1.56e-1)" "unprognostic (6.77e-2)" "unprognostic (3.89e-1)" 19.4 31.8 20.2 25.3 20.1 8.7 23.5 25.8 24.2 19.4 18.8 16.8 14.8 18.6 20.9 14.1 15.7 15.6 12.0 27.2 19.1 20.4 40.7 35.8 17.4 13.1 26.3 14.8 18.5 33.2 12.3 26.4 17.3 20.5 15.6 16.2 13.7 25.0 15.8 33.5 9.5 14.5 13.1 29.4 19.0 14.3 11.9 18.0 21.3 17.3 21.6 34.4 12.4 13.3 10.6 12.8 7.6 11.5 6.3 10.7 4.4 17.0 9.7 17.7 6.9 22.3 25.7 10.3 23.3 17.4 22.4 17.9 22.1 4.2 14.4 23.9 12.9 10.6 43.3 18.8 31.6 14.8 11.6 12.4 16.4 37.2 27.6 16.6 7.6 17.1 42.6 20.0 23.1 18.2 20.7 15.0 25.1 7.4 14.0 19.8 14.1 16.7 11.5 26.2 6.6 17.1 9.4 9.6 9.3 5.3 30.1 54.2 5.9 17.0 17.6 14.2 16.1 33.2 44.6 10.1 29.5 10.3 16.4 13.5 6.2 7.6 7.7 4.5 8.8 11.5 10.3 10.6 8.9 8.1 12.8 7.1 10.5 10.7 1.3 6.3 8.0 12.0 8.0 4.4 20.2 20.1 25.8 24.2 19.1 20.4 26.3 14.8 20.5 18.0 RAD1 "HRAD1, REC1" ENSG00000113456 "RAD1 checkpoint DNA exonuclease" O60671 5 34905264-34918989 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006692 Approved Supported Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA006692: " "prognostic unfavourable (6.30e-4)" "unprognostic (1.85e-2)" "unprognostic (9.40e-2)" "unprognostic (1.98e-3)" "unprognostic (2.00e-1)" "unprognostic (2.38e-2)" "prognostic unfavourable (1.06e-5)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.61e-3)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.11e-1)" "unprognostic (3.12e-3)" 3.1 6.5 3.4 3.2 4.9 4.8 4.4 5.2 4.7 5.4 3.2 2.9 4.6 3.8 3.7 3.5 3.3 6.6 3.5 4.4 3.7 3.5 5.6 6.1 2.9 4.0 3.3 3.0 3.4 6.0 5.3 3.1 4.3 3.7 7.4 4.5 3.6 3.3 2.6 3.1 3.7 5.8 5.2 4.7 3.8 4.7 9.4 7.6 7.2 3.1 4.8 9.3 2.6 5.8 6.8 7.2 14.0 5.1 5.9 10.4 9.2 9.0 9.7 8.0 6.4 8.0 15.2 3.3 8.2 5.4 7.9 5.6 10.9 6.8 6.8 8.1 20.7 4.3 8.7 11.1 7.5 5.3 4.8 10.5 7.0 4.6 14.4 9.0 8.2 7.2 11.3 7.9 9.4 10.3 10.4 15.2 5.3 4.7 6.2 7.5 7.9 19.0 13.0 8.5 8.0 9.3 4.2 12.7 9.6 6.5 9.6 5.0 9.1 13.4 6.6 16.8 8.8 7.2 3.0 6.8 5.9 3.1 7.7 8.7 6.5 8.0 2.9 9.4 9.3 8.0 2.3 4.8 2.9 7.6 5.3 2.6 RAD18 RNF73 ENSG00000070950 "RAD18, E3 ubiquitin protein ligase" Q9NS91 3 8775402-8963773 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006716, HPA006724, HPA008752" Supported Approved Enhanced "Nucleoplasm,Nuclear bodies" "Nuclear bodies" Nucleoplasm "HPA006716: , HPA006724: , HPA008752: AB_2668129" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-3)" "unprognostic (2.73e-2)" "unprognostic (6.15e-2)" "prognostic unfavourable (1.12e-4)" "unprognostic (2.01e-1)" "unprognostic (9.76e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "prognostic unfavourable (3.73e-4)" "prognostic unfavourable (3.65e-5)" "unprognostic (1.97e-2)" "unprognostic (1.51e-1)" "unprognostic (7.92e-2)" "unprognostic (1.89e-2)" 6.2 5.7 7.4 5.6 12.7 7.9 9.5 16.4 11.4 5.5 6.6 3.9 5.4 17.7 6.5 3.7 7.6 4.9 5.6 4.4 4.7 3.3 4.3 5.7 5.9 7.6 8.4 6.9 7.1 4.2 3.4 6.9 6.9 5.7 7.4 9.0 3.5 7.5 3.5 3.7 8.5 10.5 6.0 7.8 8.5 5.1 9.5 9.8 16.6 6.7 4.7 7.5 6.1 6.8 3.7 6.3 8.7 3.0 4.3 5.5 1.5 9.7 9.3 7.8 4.6 1.9 4.2 9.5 15.5 5.3 15.0 10.3 8.4 6.3 12.1 3.0 8.8 3.4 8.2 8.0 15.3 7.4 10.3 10.3 9.3 5.0 1.2 13.5 8.9 1.5 2.9 14.8 10.1 4.8 10.9 12.0 13.0 11.3 13.7 9.6 10.8 17.1 10.9 8.6 9.5 4.3 7.5 3.2 7.4 6.9 6.6 5.0 6.9 6.0 4.0 12.4 6.8 10.6 13.2 6.1 9.3 26.3 9.2 15.0 9.1 7.4 2.7 8.7 3.0 3.0 5.5 3.7 4.0 5.2 3.4 3.7 4.3 3.2 1.2 4.3 1.8 6.3 5.0 1.5 7.4 12.7 16.4 11.4 4.7 3.3 8.4 6.9 5.7 9.8 RAD54L2 "ARIP4, KIAA0809, SRISNF2L" ENSG00000164080 "RAD54 like 2" Q9Y4B4 3 51541144-51668667 "Enzymes, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035004, HPA039992, HPA077351" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA035004: AB_10671930, HPA039992: , HPA077351: " "unprognostic (1.46e-2)" "unprognostic (3.67e-2)" "unprognostic (2.61e-1)" "unprognostic (5.01e-2)" "unprognostic (1.15e-1)" "unprognostic (4.38e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-2)" "unprognostic (9.24e-2)" "unprognostic (2.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.51e-1)" "prognostic favourable (1.71e-5)" "unprognostic (3.72e-2)" "unprognostic (3.19e-1)" "unprognostic (3.30e-2)" "unprognostic (6.63e-2)" 4.4 4.1 3.3 3.5 4.3 5.2 4.1 7.8 4.3 3.6 4.4 2.2 5.3 4.6 3.6 3.9 2.5 3.1 3.4 3.5 3.4 8.8 4.2 3.8 3.4 5.6 5.0 5.3 3.9 4.9 3.8 3.5 3.7 4.2 7.3 4.6 4.1 4.3 4.1 4.7 4.4 4.7 4.2 5.2 3.8 3.5 6.9 5.2 6.5 7.1 6.3 8.3 4.0 5.6 4.4 11.4 11.2 6.4 4.6 6.0 4.8 6.8 6.6 6.3 7.8 3.3 14.8 1.4 8.4 4.4 17.9 6.0 8.2 7.8 4.0 12.7 9.5 5.1 5.8 14.1 7.6 5.2 4.8 10.1 9.8 7.3 8.3 8.1 5.2 4.3 12.6 6.4 9.0 4.8 5.8 8.8 2.0 3.3 7.3 4.7 8.9 7.6 7.3 4.9 4.8 8.5 9.5 7.0 8.0 7.1 9.3 8.7 8.8 15.0 7.5 8.0 8.8 6.5 4.8 4.7 8.1 6.0 8.3 4.3 7.1 6.6 5.2 6.9 4.7 5.4 2.2 6.3 7.1 5.2 6.3 4.0 RAD9A RAD9 ENSG00000172613 "RAD9 checkpoint clamp component A" Q99638 11 67317871-67398410 "Enzymes, Predicted intracellular proteins" "DNA damage" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006725, HPA048155" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA006725: AB_1856041, HPA048155: " "unprognostic (7.64e-2)" "prognostic favourable (6.95e-4)" "unprognostic (8.83e-3)" "unprognostic (1.13e-1)" "unprognostic (2.68e-1)" "unprognostic (2.12e-3)" "unprognostic (9.64e-3)" "unprognostic (1.05e-2)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (9.19e-2)" "unprognostic (2.50e-2)" "prognostic unfavourable (2.82e-5)" "unprognostic (6.16e-2)" "unprognostic (3.72e-3)" "unprognostic (2.19e-1)" "prognostic favourable (7.52e-6)" 5.4 5.2 7.0 10.6 8.4 10.8 6.1 7.7 6.3 6.7 11.8 8.5 5.1 14.2 7.1 4.1 8.2 12.1 6.3 6.1 3.8 3.5 6.9 9.4 9.5 9.0 7.8 2.5 6.8 20.1 3.7 7.2 10.2 5.5 8.6 3.3 4.9 12.8 8.1 7.8 12.8 17.5 5.5 4.1 10.7 11.3 7.2 6.0 18.2 11.7 7.2 16.8 6.2 7.1 6.7 5.1 8.9 3.9 4.7 9.0 3.2 6.7 11.0 5.8 8.3 1.7 0.8 7.8 4.3 2.9 5.0 4.3 13.1 12.9 8.1 8.1 0.9 11.4 3.4 3.3 0.7 7.7 9.5 10.9 5.9 6.5 2.4 7.1 14.4 2.1 3.4 4.3 1.8 3.3 8.8 9.0 1.0 20.9 13.8 13.8 8.8 8.3 11.5 7.9 9.2 1.3 5.4 6.7 7.2 6.0 16.5 13.6 11.6 6.8 2.5 7.2 9.4 14.6 5.1 9.6 8.9 7.1 4.8 7.0 5.9 8.0 3.2 8.9 9.0 3.6 6.4 6.7 7.2 7.3 2.1 5.3 4.9 5.7 4.7 4.7 3.9 5.1 3.9 3.2 7.0 8.4 7.7 6.3 3.8 3.5 7.8 2.5 5.5 6.0 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664226 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 53.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002640, CAB019291" Approved Approved "Nuclear speckles" "Nuclear speckles" "CAB019291: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 19.5 15.6 15.1 14.7 17.1 32.2 17.5 35.2 18.9 19.9 20.3 21.1 19.6 18.4 24.9 15.7 24.6 18.6 20.2 39.3 15.3 11.0 21.7 36.2 19.7 15.7 16.0 13.4 24.9 31.3 30.7 16.9 24.8 14.3 18.8 19.2 25.0 18.3 18.4 79.7 23.9 29.6 23.7 13.8 22.1 23.7 16.7 17.8 27.7 26.9 27.9 26.1 20.5 20.4 6.6 9.3 53.9 9.9 8.5 8.6 7.7 15.1 17.4 26.6 20.5 23.1 18.7 53.5 23.1 39.2 30.6 34.8 13.6 12.5 15.9 11.1 35.8 9.7 28.0 20.5 31.9 27.7 21.9 21.4 21.0 12.6 23.4 20.8 20.3 17.2 20.7 31.5 25.6 21.9 15.5 41.8 29.5 25.9 26.7 15.3 27.0 23.7 21.6 23.4 20.0 18.3 22.9 8.3 17.5 18.9 18.3 12.3 30.4 27.5 15.7 21.1 20.1 17.6 25.7 32.6 51.8 34.2 18.2 24.3 22.4 11.3 9.7 18.4 7.4 9.9 7.5 6.6 7.3 7.2 9.3 6.3 7.5 7.6 53.9 8.5 9.6 4.2 8.6 7.7 15.1 17.1 35.2 18.9 15.3 11.0 16.0 13.4 14.3 17.8 RAG1 "MGC43321, RNF74" ENSG00000166349 "Recombination activating 1" P15918 11 36510709-36593156 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA recombination, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Multifunctional enzyme, Nuclease, Transferase" "Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 62 "lymphoid tissue: 462.4" "Group enriched" "Detected in some" 110 "MOLT-4: 65.8;REH: 62.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043939 Supported Nucleoplasm Nucleoplasm "HPA043939: " "unprognostic (7.35e-2)" "unprognostic (1.57e-3)" "unprognostic (8.75e-2)" "unprognostic (3.44e-1)" "unprognostic (2.14e-1)" "unprognostic (1.46e-2)" "unprognostic (2.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.43e-1)" "unprognostic (1.54e-2)" "unprognostic (5.98e-3)" "unprognostic (1.28e-1)" "unprognostic (1.16e-9)" "unprognostic (2.16e-2)" "unprognostic (1.04e-1)" "unprognostic (2.53e-4)" "unprognostic (1.53e-1)" 0.7 2.3 0.5 0.5 0.5 7.4 0.7 0.5 0.5 0.5 0.6 0.5 0.5 1.2 0.5 1.3 0.5 0.6 0.5 0.6 0.5 0.2 2.4 1.2 0.8 0.5 0.5 0.5 0.6 1.1 1.9 0.5 0.8 0.5 0.5 0.4 0.5 1.5 0.5 0.5 0.2 1.5 0.5 0.5 4.4 0.8 0.9 0.5 462.4 4.5 0.5 0.8 0.7 0.5 0.2 0.3 0.0 0.0 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 65.8 0.0 0.5 0.0 62.9 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.8 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.5 0.5 0.5 0.5 0.5 0.2 0.5 0.5 0.5 0.5 RARS DALRD1 ENSG00000113643 "Arginyl-tRNA synthetase" P54136 5 168486445-168519299 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003979, HPA004130" Approved Enhanced Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA003979: AB_1856083, HPA004130: AB_1856084" "unprognostic (1.06e-2)" "unprognostic (1.92e-2)" "unprognostic (2.74e-3)" "unprognostic (2.82e-2)" "unprognostic (2.50e-1)" "prognostic unfavourable (7.59e-5)" "prognostic unfavourable (1.10e-8)" "unprognostic (3.26e-3)" "unprognostic (5.16e-1)" "unprognostic (4.22e-2)" "unprognostic (2.92e-2)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" "unprognostic (6.43e-2)" "unprognostic (2.35e-1)" "unprognostic (2.39e-1)" "unprognostic (1.33e-2)" 21.8 26.3 16.0 18.3 15.3 6.2 22.6 17.1 18.4 21.2 29.4 9.1 20.4 33.3 22.9 21.4 34.7 19.5 14.4 21.7 19.8 12.3 29.8 33.5 18.7 18.6 13.9 15.2 21.3 33.0 19.9 34.5 30.3 15.8 18.9 27.4 15.5 34.0 15.4 27.8 27.9 48.7 21.5 14.5 22.1 24.4 17.2 11.8 20.5 21.5 32.3 23.7 22.4 22.6 11.1 21.8 5.2 17.7 16.8 16.3 11.7 27.1 32.2 23.9 26.4 33.1 37.9 41.1 40.0 34.4 41.7 48.8 54.7 29.6 28.9 32.8 38.0 26.4 31.2 53.8 54.4 30.0 21.5 19.4 29.4 34.3 28.7 45.7 20.7 29.1 28.8 45.4 21.8 33.3 28.9 14.7 44.6 25.1 19.0 18.3 39.2 22.0 8.4 34.8 27.4 37.1 31.0 22.8 28.0 30.6 35.4 41.2 32.1 19.2 33.0 30.2 27.8 23.3 46.6 14.6 26.8 29.6 32.9 32.7 28.7 3.4 14.4 5.2 12.5 17.7 14.3 11.1 12.6 13.3 21.8 6.6 15.6 16.3 4.0 16.8 16.4 10.3 12.8 11.7 16.0 15.3 17.1 18.4 19.8 12.3 13.9 15.2 15.8 11.8 RARS2 "DALRD2, dJ382I10.6, MGC14993, MGC23778, PRO1992, RARSL" ENSG00000146282 "Arginyl-tRNA synthetase 2, mitochondrial" Q5T160 6 87514378-87590003 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039987, HPA042645" Uncertain "HPA039987: , HPA042645: " "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-2)" "unprognostic (6.98e-2)" "unprognostic (9.27e-2)" "unprognostic (5.41e-2)" "unprognostic (6.61e-2)" "unprognostic (4.30e-2)" "unprognostic (1.88e-1)" "unprognostic (1.08e-3)" "unprognostic (8.28e-2)" "unprognostic (2.20e-1)" "unprognostic (7.56e-3)" "unprognostic (1.62e-1)" "unprognostic (1.89e-2)" "unprognostic (5.73e-2)" "unprognostic (7.16e-3)" 27.0 44.1 13.3 21.1 15.9 16.0 22.9 24.0 17.3 25.1 21.4 18.6 25.2 17.5 35.5 25.5 20.4 21.1 19.2 21.5 14.4 12.8 23.7 32.1 20.5 24.4 17.3 14.2 22.2 30.1 20.5 36.9 28.3 17.2 20.7 23.1 24.0 23.5 27.7 23.0 20.4 30.5 24.7 16.8 21.1 20.5 23.9 13.6 28.0 21.2 20.5 27.3 24.3 20.2 16.7 18.9 22.8 20.2 18.1 28.8 16.2 10.0 9.9 23.9 25.9 24.3 26.6 17.0 24.0 28.7 16.6 21.1 19.1 11.2 12.7 14.3 24.6 14.0 20.1 13.8 23.6 9.3 19.0 13.0 12.6 30.3 30.6 15.4 11.3 26.5 13.4 14.0 17.8 21.9 30.2 12.6 24.5 18.4 5.0 16.4 15.5 10.7 10.1 24.1 11.1 20.4 21.0 21.6 29.2 12.6 6.3 16.8 11.7 23.6 14.8 11.1 8.9 12.1 19.8 13.3 22.4 10.6 17.3 16.3 19.1 15.9 19.1 22.8 18.1 19.3 21.3 16.7 23.4 17.0 16.7 16.2 23.0 19.1 11.6 18.1 20.2 18.9 28.8 16.2 13.3 15.9 24.0 17.3 14.4 12.8 17.3 14.2 17.2 13.6 RBBP6 "P2P-R, PACT, SNAMA" ENSG00000122257 "RB binding protein 6, ubiquitin ligase" Q7Z6E9 16 24537693-24572863 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA replication, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032866, HPA041725, HPA043544" Approved Enhanced "Nuclear speckles" "Nuclear speckles" "CAB032866: AB_2177791, HPA041725: , HPA043544: " "unprognostic (1.04e-1)" "unprognostic (5.08e-2)" "unprognostic (3.35e-1)" "unprognostic (3.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.15e-2)" "unprognostic (1.08e-2)" "unprognostic (6.60e-2)" "unprognostic (2.70e-3)" "unprognostic (1.29e-2)" "unprognostic (1.77e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (2.83e-2)" 15.1 17.6 17.2 14.0 16.4 81.4 17.9 33.0 15.7 17.8 18.8 16.3 19.8 10.2 23.2 18.7 15.3 21.2 17.6 14.7 15.0 13.2 13.1 15.8 15.7 18.1 18.7 12.2 27.2 14.4 20.7 23.1 73.9 15.4 18.2 14.4 18.4 13.7 14.7 19.2 19.2 16.4 18.4 19.2 18.6 16.4 25.1 18.7 24.3 18.6 11.8 15.5 17.9 17.9 3.8 6.9 8.5 3.7 6.5 4.2 1.0 17.6 9.2 21.8 22.6 16.7 17.4 23.6 14.3 13.2 13.1 14.2 10.2 14.3 24.5 10.8 12.1 17.0 23.3 12.5 21.7 13.4 18.1 21.1 26.5 29.0 13.0 28.0 12.6 15.1 17.4 17.0 20.1 18.7 26.5 22.4 15.1 18.1 22.6 25.3 25.0 8.8 31.1 22.1 21.6 12.6 15.8 17.5 15.3 20.1 18.1 25.3 14.1 24.9 16.2 16.3 12.0 14.0 15.3 20.0 19.8 30.9 13.1 18.6 13.4 8.5 2.3 3.7 4.0 3.7 4.2 3.8 4.1 2.8 1.6 3.8 3.5 4.0 5.0 6.5 2.1 6.9 3.1 1.0 17.2 16.4 33.0 15.7 15.0 13.2 18.7 12.2 15.4 18.7 RBKS "DKFZp686G13268, RBSK" ENSG00000171174 Ribokinase Q9H477 2 27781364-27891098 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 10.2;RPTEC TERT1: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019725, HPA028285" Enhanced Approved Cytosol Cytosol "HPA019725: AB_1856105, HPA028285: AB_10601480" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" "unprognostic (2.51e-2)" "unprognostic (5.54e-3)" "unprognostic (4.15e-3)" "unprognostic (2.44e-1)" "unprognostic (1.43e-2)" "unprognostic (4.77e-2)" "unprognostic (2.45e-1)" "unprognostic (5.35e-2)" "unprognostic (1.46e-1)" "unprognostic (3.98e-1)" "unprognostic (1.20e-1)" "unprognostic (1.19e-1)" "unprognostic (1.72e-1)" "unprognostic (1.74e-1)" "unprognostic (9.27e-2)" 14.4 22.2 2.5 2.4 5.2 4.1 2.2 2.1 4.1 2.6 3.0 1.7 4.9 12.4 4.7 4.7 3.1 7.4 10.7 3.5 3.7 4.3 15.1 22.6 10.4 0.8 3.0 2.4 24.2 2.4 3.5 10.3 6.2 12.3 6.9 2.4 2.2 1.4 16.8 7.6 1.0 11.8 3.8 4.7 1.7 1.6 4.8 1.4 0.3 4.5 2.8 1.1 4.8 12.0 5.8 5.1 5.6 3.8 4.9 6.5 3.4 3.0 2.0 0.3 0.4 0.4 0.7 2.0 0.8 0.6 0.4 0.6 4.7 1.5 1.0 10.2 1.7 1.2 0.2 1.0 0.8 0.4 0.2 0.1 0.5 4.0 1.5 0.8 0.2 1.0 1.7 2.6 3.6 0.6 0.1 1.3 2.0 4.0 0.6 2.2 0.0 1.7 0.9 0.2 0.7 21.6 0.2 0.8 1.2 2.9 3.9 1.7 1.7 4.5 0.1 0.7 0.5 1.8 1.2 6.6 7.7 2.0 1.9 3.0 0.1 5.6 3.8 1.9 3.0 1.6 6.1 5.8 4.0 6.5 5.1 4.6 4.2 3.6 5.6 4.9 0.8 0.8 5.8 3.4 2.5 5.2 2.1 4.1 3.7 4.3 3.0 2.4 12.3 1.4 RBP3 "D10S64, D10S65, D10S66, RP66" ENSG00000265203 "Retinol binding protein 3" P10745 10 47348371-47357875 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Transport "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "retina: 135.2" "Group enriched" "Detected in some" 8 "HaCaT: 2.6;HDLM-2: 2.4;SH-SY5Y: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041301, HPA044239" Enhanced "Secreted in other tissues" "HPA041301: , HPA044239: " "unprognostic (3.48e-2)" "unprognostic (4.78e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.58e-2)" "unprognostic (5.09e-2)" "unprognostic (5.14e-3)" "unprognostic (7.44e-2)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 135.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RBX1 "BA554C12.1, RNF75, ROC1" ENSG00000100387 "Ring-box 1" P62877 22 40951347-40973309 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003038 Supported Nucleoplasm Nucleoplasm "HPA003038: AB_1079827" "unprognostic (2.34e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (1.60e-3)" "unprognostic (2.30e-1)" "unprognostic (2.92e-2)" "unprognostic (1.82e-3)" "unprognostic (1.74e-1)" "unprognostic (6.61e-2)" "prognostic favourable (6.63e-4)" "unprognostic (5.01e-3)" "unprognostic (2.19e-1)" "unprognostic (4.99e-3)" "unprognostic (2.22e-2)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" "unprognostic (3.05e-2)" 24.1 27.9 41.6 22.2 35.3 37.6 32.9 28.0 35.7 23.0 22.7 27.4 15.8 18.4 19.4 43.7 27.6 21.2 16.6 39.2 38.3 37.4 34.2 28.3 23.6 28.1 40.4 22.3 18.5 15.6 12.3 19.5 54.1 32.4 20.3 23.9 22.1 21.3 20.8 46.5 21.8 23.0 23.2 45.2 26.4 21.4 16.4 24.8 31.7 31.1 37.4 34.4 19.5 19.4 33.4 60.7 32.2 41.5 23.9 38.5 62.6 33.1 19.0 35.9 17.8 25.5 30.5 20.2 26.7 24.6 40.3 35.7 30.7 16.0 29.1 18.1 26.2 19.0 34.0 30.6 42.7 33.8 54.2 18.0 27.8 37.4 21.9 43.9 23.4 25.2 24.8 29.1 21.1 34.1 21.2 29.6 35.5 40.6 26.4 50.7 19.7 20.0 34.7 24.9 36.6 46.0 21.5 16.9 11.0 23.5 23.6 23.9 20.3 30.3 22.6 24.6 25.4 20.6 25.4 25.2 23.1 43.1 30.8 22.4 27.3 32.2 37.2 29.9 24.7 37.0 23.1 33.4 30.9 26.0 37.6 29.4 27.0 29.2 12.6 23.9 41.5 60.7 38.5 62.6 41.6 35.3 28.0 35.7 38.3 37.4 40.4 22.3 32.4 24.8 RC3H2 "FLJ20301, FLJ20713, MNAB, RNF164" ENSG00000056586 "Ring finger and CCCH-type domains 2" Q9HBD1 9 122844556-122905341 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "Repressor, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042863, HPA062144" Approved Enhanced Vesicles Vesicles "HPA042863: , HPA062144: " "unprognostic (6.05e-2)" "unprognostic (7.87e-2)" "unprognostic (7.24e-2)" "unprognostic (1.66e-1)" "unprognostic (4.08e-3)" "unprognostic (2.37e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "prognostic favourable (5.50e-4)" "unprognostic (1.36e-1)" "unprognostic (1.68e-1)" "unprognostic (2.16e-1)" "unprognostic (1.26e-1)" 16.4 10.7 25.4 14.1 28.8 30.6 14.1 18.7 27.6 17.1 13.0 10.5 14.4 11.0 14.6 9.7 16.5 12.2 12.6 15.7 18.1 11.2 15.0 14.8 16.2 19.2 12.3 25.3 14.7 9.7 19.0 16.2 16.3 12.6 11.5 13.1 9.4 13.2 13.9 16.1 13.8 13.0 16.3 14.4 15.2 12.8 12.8 13.2 18.9 15.0 11.5 18.8 14.1 13.7 8.6 9.6 12.4 10.4 4.9 8.9 3.7 9.8 14.3 19.1 10.3 10.2 12.1 10.6 12.6 13.8 14.9 13.0 17.3 10.4 16.5 10.3 16.8 23.1 20.4 14.8 16.4 7.6 8.1 9.4 25.8 11.4 13.4 11.1 15.1 11.6 14.4 14.5 20.6 20.4 13.2 12.1 18.8 13.2 10.9 7.8 9.5 13.3 11.0 31.6 10.6 14.5 7.8 22.5 15.6 22.3 13.8 11.4 16.6 9.4 20.2 11.5 9.6 15.6 22.4 8.5 13.8 18.0 13.1 9.9 12.9 12.4 6.6 8.5 8.9 10.4 7.3 6.5 7.3 8.9 5.8 8.6 7.0 6.8 11.8 4.9 9.3 9.6 7.1 3.7 25.4 28.8 18.7 27.6 18.1 11.2 12.3 25.3 12.6 13.2 RCE1 "FACE-2, FACE2, hRCE1, RCE1A, RCE1B" ENSG00000173653 "Ras converting CAAX endopeptidase 1" Q9Y256 11 66842835-66846546 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074124 Approved "HPA074124: " "unprognostic (1.11e-1)" "unprognostic (7.23e-2)" "unprognostic (1.15e-1)" "unprognostic (8.16e-3)" "unprognostic (3.11e-1)" "unprognostic (6.40e-3)" "unprognostic (1.98e-3)" "unprognostic (7.69e-3)" "unprognostic (1.39e-1)" "unprognostic (9.14e-3)" "unprognostic (2.35e-3)" "unprognostic (5.31e-3)" "unprognostic (1.06e-1)" "unprognostic (4.48e-3)" "unprognostic (2.17e-2)" "unprognostic (1.04e-1)" "unprognostic (4.28e-2)" 12.3 9.0 7.6 11.9 9.4 19.5 15.9 27.5 9.4 10.8 13.0 9.2 9.3 11.3 10.9 11.8 15.9 9.6 9.7 5.9 6.6 9.4 13.7 7.4 9.7 17.6 8.9 5.1 13.2 23.9 10.2 12.6 20.8 5.6 13.7 9.5 11.2 14.9 13.9 5.6 22.1 13.0 6.7 5.0 12.0 10.2 17.1 5.4 14.8 14.3 10.5 13.6 9.9 9.9 11.4 22.0 12.2 17.9 10.0 17.1 12.4 10.6 12.0 7.4 6.9 4.6 4.0 16.1 5.7 5.6 8.9 8.1 22.5 23.2 8.1 10.8 5.4 19.3 8.6 8.6 5.2 9.7 9.5 7.2 8.5 8.6 16.4 9.1 10.9 6.5 16.5 10.1 9.0 7.3 9.9 12.8 4.5 20.6 13.2 18.2 21.5 12.3 10.6 5.2 15.8 9.8 5.8 9.1 8.2 8.0 11.2 35.1 13.0 7.9 4.3 12.3 9.2 13.2 8.7 6.9 6.9 8.9 8.3 9.7 8.8 12.2 15.6 10.7 13.7 17.9 12.5 11.4 11.5 17.1 14.4 9.0 9.4 14.3 5.1 10.0 15.3 22.0 4.8 12.4 7.6 9.4 27.5 9.4 6.6 9.4 8.9 5.1 5.6 5.4 RCHY1 "ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363" ENSG00000163743 "Ring finger and CHY zinc finger domain containing 1" Q96PM5 4 75479037-75514764 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030338, HPA030339" Approved Supported Nucleoplasm,Vesicles,Cytosol Cytosol "Nucleoplasm, Vesicles" "HPA030338: , HPA030339: AB_10603232" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "prognostic favourable (9.09e-4)" "unprognostic (1.90e-1)" "unprognostic (3.45e-3)" "unprognostic (1.19e-2)" "unprognostic (7.87e-3)" "unprognostic (5.82e-2)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.60e-2)" "prognostic favourable (3.62e-5)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "prognostic favourable (7.89e-5)" 8.8 12.1 15.7 9.9 20.1 15.6 17.8 20.7 16.8 10.2 12.7 9.8 8.7 9.0 11.0 7.5 8.4 12.9 7.2 17.6 14.1 16.2 17.1 12.5 10.4 12.2 15.9 15.7 16.2 10.6 14.9 13.0 10.5 17.1 12.0 14.2 7.7 12.3 11.3 29.7 5.9 9.2 12.4 16.7 12.2 10.3 13.4 15.4 14.9 20.3 8.0 12.7 9.7 12.1 4.4 7.4 18.9 8.8 4.6 7.4 4.3 6.0 3.1 9.4 8.7 9.9 8.7 5.4 4.1 9.6 8.5 10.0 8.6 7.5 10.1 7.8 5.9 3.6 23.8 7.2 13.0 8.2 7.8 13.1 5.9 11.0 8.5 17.6 7.2 8.0 9.1 9.7 9.2 17.1 12.0 10.3 19.8 9.8 16.1 7.1 15.6 5.5 8.7 22.1 8.5 13.2 10.4 14.5 8.0 6.7 15.8 17.4 8.9 8.0 6.7 5.6 5.6 5.0 6.8 10.9 7.8 14.3 6.8 12.5 8.8 18.9 8.8 8.5 4.3 5.2 7.4 4.4 5.3 5.0 7.4 2.2 3.9 5.5 3.7 4.6 4.7 3.8 5.2 4.3 15.7 20.1 20.7 16.8 14.1 16.2 15.9 15.7 17.1 15.4 RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294612-73325281 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 134.3" "Cell line enhanced" "Detected in many" "ASC diff: 46.6;BJ: 33.4;CACO-2: 29.8;HDLM-2: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 4.4" "Group enriched" "Detected in many" 5 "granulocytes: 4.4;T-cells: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" "Lipid droplets" "HPA049199: " "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.80e-2)" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.18e-3)" "unprognostic (8.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.23e-2)" 18.3 3.2 2.7 9.5 3.3 0.7 11.8 1.7 2.8 8.2 18.7 2.9 10.0 13.6 5.9 5.8 9.4 4.4 21.9 9.6 2.3 2.4 19.6 37.5 8.7 4.8 4.1 1.7 4.9 14.8 3.7 17.9 20.9 8.7 12.4 6.4 134.3 22.6 5.7 3.4 4.4 34.1 14.0 6.9 5.6 15.3 8.0 2.1 2.0 3.5 7.3 6.5 12.8 6.5 0.6 0.7 4.4 0.6 0.2 2.3 0.5 4.1 12.1 1.3 5.6 46.6 3.4 12.4 33.4 5.4 1.3 2.2 29.8 12.0 2.9 4.4 18.6 11.1 6.1 4.8 2.7 33.5 15.3 5.2 12.0 9.1 1.8 2.4 5.7 2.0 6.2 5.2 4.9 4.9 5.9 4.3 2.2 1.8 2.5 1.0 1.6 5.9 2.2 1.4 1.7 9.0 6.0 0.8 1.0 2.8 20.8 1.7 4.1 1.3 7.4 2.0 3.4 9.1 2.5 2.8 2.9 2.4 1.6 2.2 4.6 4.4 0.6 1.1 1.2 0.3 0.7 0.6 1.3 1.4 0.7 0.1 2.3 1.2 0.8 0.2 0.5 0.2 0.7 0.5 2.7 3.3 1.7 1.8 2.3 2.4 4.1 1.7 8.7 2.1 RDH11 "ARSDR1, MDT1, SDR7C1" ENSG00000072042 "Retinol dehydrogenase 11 (all-trans/9-cis/11-cis)" Q8TC12 14 67676801-67695814 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cataract, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 204.2" "Low cell line specificity" "Detected in all" "Cancer enriched" "Detected in all" 13 "prostate cancer: 286.6" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046011 Enhanced "Intracellular and membrane" 9100000 "CAB046011: AB_11129613" "unprognostic (1.38e-1)" "unprognostic (6.86e-3)" "unprognostic (1.77e-1)" "prognostic favourable (2.62e-4)" "unprognostic (6.06e-2)" "prognostic unfavourable (2.89e-5)" "unprognostic (9.29e-2)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.58e-2)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "prognostic favourable (1.30e-7)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (4.74e-2)" 8.8 24.9 18.3 8.9 19.0 5.1 10.8 15.7 25.3 13.0 10.8 24.3 16.1 12.3 13.0 31.4 13.6 9.3 15.6 7.2 18.5 19.9 40.7 51.6 12.6 7.2 21.8 16.6 11.4 15.3 28.7 13.1 8.3 31.1 204.2 12.0 40.4 16.2 13.5 3.6 11.2 10.2 15.8 32.5 10.8 11.6 10.3 15.8 12.5 24.2 8.1 9.5 14.8 11.4 11.5 17.0 62.4 19.7 14.4 20.8 28.2 46.9 21.4 19.0 21.6 30.5 27.7 15.9 17.9 35.4 22.5 40.9 17.8 57.2 8.1 13.9 16.8 37.7 27.4 39.5 30.7 16.4 11.1 16.9 11.4 17.6 29.3 6.2 12.4 25.8 26.2 29.2 24.9 25.6 13.2 27.0 20.4 24.9 18.2 9.7 10.7 24.6 13.8 23.6 11.7 51.4 24.2 19.8 16.6 18.8 23.9 24.9 26.7 9.9 19.7 24.2 27.7 10.4 12.8 12.8 10.1 10.6 31.5 17.3 19.6 62.4 19.7 28.2 18.7 16.1 20.4 11.3 20.5 18.5 14.5 11.5 20.8 20.1 3.3 14.4 16.9 17.0 17.6 28.2 18.3 19.0 15.7 25.3 18.5 19.9 21.8 16.6 31.1 15.8 RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 39.4;retina: 127.9" "Cell line enhanced" "Detected in some" "ASC diff: 19.5;ASC TERT1: 16.8;hTEC/SVTERT24-B: 10.2;LHCN-M2: 10.1;U-87 MG: 18.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Approved Vesicles "Intracellular and membrane" Vesicles "HPA063345: " "unprognostic (1.04e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.05e-1)" "unprognostic (1.26e-3)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (3.46e-2)" "unprognostic (2.12e-3)" "unprognostic (3.27e-2)" 39.4 0.7 0.6 2.8 0.8 0.2 14.9 0.5 0.8 1.0 7.6 1.0 1.5 8.6 1.9 4.5 2.4 2.2 4.8 3.9 1.0 0.5 3.7 27.2 0.7 1.6 0.8 0.8 1.4 1.5 0.0 0.6 0.4 1.5 1.8 1.9 127.9 3.2 1.0 3.1 1.0 9.4 8.8 1.1 0.9 2.7 0.9 1.0 0.3 1.1 2.6 0.7 2.0 2.5 0.4 2.3 2.1 0.9 1.5 2.6 0.4 0.4 0.9 0.5 0.3 19.5 16.8 0.4 2.5 2.8 0.5 1.0 0.3 5.2 0.6 0.4 1.4 0.2 0.2 0.0 0.4 0.6 0.8 0.1 1.1 1.3 0.5 0.0 0.2 7.2 0.6 10.2 0.0 0.2 0.1 0.9 10.1 0.4 0.2 0.1 0.2 1.5 0.3 0.3 0.3 0.1 0.5 0.2 0.7 0.1 0.3 2.3 0.4 0.4 0.3 1.0 1.0 0.7 0.6 0.8 0.3 0.1 18.1 0.2 0.2 0.3 0.6 2.1 0.4 0.9 0.2 0.4 1.2 2.6 1.2 0.3 1.0 0.4 0.9 1.5 0.9 2.3 0.2 0.4 0.6 0.8 0.5 0.8 1.0 0.5 0.8 0.8 1.5 1.0 RECQL "RecQ1, RecQL1" ENSG00000004700 "RecQ like helicase" P46063 12 21468911-21501669 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009743, HPA030960, HPA064259" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB009743: AB_655306, HPA030960: AB_10794912, HPA064259: " "unprognostic (9.70e-3)" "unprognostic (2.55e-2)" "unprognostic (1.86e-2)" "unprognostic (6.25e-3)" "unprognostic (2.47e-1)" "unprognostic (1.39e-1)" "unprognostic (8.97e-3)" "unprognostic (1.89e-3)" "unprognostic (8.74e-2)" "prognostic unfavourable (3.15e-4)" "unprognostic (3.77e-3)" "unprognostic (3.78e-2)" "unprognostic (2.85e-1)" "unprognostic (1.27e-1)" "unprognostic (1.09e-1)" "unprognostic (2.99e-1)" "unprognostic (3.69e-2)" 32.7 15.8 10.0 22.0 12.7 10.8 18.2 10.9 11.2 18.0 16.3 9.4 11.0 7.5 19.8 14.4 18.7 14.6 14.1 17.9 11.2 7.2 19.6 18.0 19.5 25.7 15.3 7.6 16.0 11.9 8.0 14.8 17.1 12.0 14.0 12.7 6.7 13.1 12.4 15.0 12.4 15.5 20.5 19.5 34.0 12.9 10.8 13.0 27.4 17.4 14.3 25.0 22.6 13.0 19.3 15.2 11.3 20.7 23.1 28.0 13.8 17.5 17.8 13.5 10.0 27.4 34.5 15.7 34.0 28.7 21.9 25.6 19.5 14.7 21.1 13.1 23.1 12.9 14.4 16.9 31.3 35.3 9.6 25.7 19.8 8.2 10.6 17.8 19.5 19.2 8.7 31.1 22.9 24.6 9.0 10.3 28.8 8.5 19.5 20.8 22.5 12.1 16.1 54.9 16.3 8.4 12.1 3.6 10.8 25.3 6.8 17.8 17.3 11.4 33.1 30.9 20.1 27.0 31.5 4.2 12.4 46.3 26.1 10.5 22.7 9.3 11.8 11.3 21.9 20.7 21.3 19.3 20.5 21.0 15.2 16.0 13.6 18.8 5.5 23.1 18.8 11.6 28.0 13.8 10.0 12.7 10.9 11.2 11.2 7.2 15.3 7.6 12.0 13.0 RECQL5 "FLJ90603, RecQ5" ENSG00000108469 "RecQ like helicase 5" O94762 17 75626845-75667189 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, DNA replication" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029971 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA029971: AB_10611389" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "prognostic unfavourable (1.73e-6)" "unprognostic (8.39e-2)" "unprognostic (2.34e-2)" "unprognostic (3.57e-3)" "unprognostic (5.83e-2)" "unprognostic (3.15e-1)" "unprognostic (5.84e-2)" "prognostic favourable (4.34e-4)" "unprognostic (4.07e-2)" "unprognostic (7.01e-2)" "unprognostic (6.37e-2)" "unprognostic (1.42e-1)" "unprognostic (4.78e-1)" "unprognostic (1.81e-2)" 7.4 12.9 12.6 11.7 16.0 10.0 9.8 11.4 17.7 9.4 10.6 24.4 17.4 22.9 10.5 13.2 20.4 11.8 12.4 6.7 12.9 8.6 14.9 15.8 8.4 16.8 14.5 11.0 14.3 10.8 17.6 21.9 32.3 14.3 12.2 9.8 13.2 15.6 14.0 6.8 21.1 23.2 9.6 13.2 16.6 23.8 21.0 17.0 12.1 21.4 6.2 16.0 12.1 12.8 5.2 16.4 6.0 3.9 3.8 4.2 3.2 11.0 20.5 8.3 11.7 11.6 7.8 19.1 8.2 6.9 10.7 9.5 9.0 11.8 13.1 8.9 7.2 10.5 8.6 9.8 10.2 7.0 16.1 23.9 24.8 13.0 11.6 7.7 11.9 11.0 12.1 10.6 12.8 13.9 12.0 11.7 7.9 9.8 15.8 10.5 5.4 15.9 12.8 19.4 13.2 9.0 13.2 10.0 9.7 8.9 16.1 11.0 28.9 6.2 7.0 13.8 15.9 7.5 8.4 16.7 9.5 12.6 11.3 7.7 9.9 6.0 3.1 4.4 4.2 3.9 2.7 3.6 2.7 3.1 3.8 5.2 4.1 2.9 2.1 3.8 1.9 16.4 2.2 3.2 12.6 16.0 11.4 17.7 12.9 8.6 14.5 11.0 14.3 17.0 REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 63.6" "Cell line enhanced" "Detected in some" "A-431: 2.3;BJ: 4.8;HMC-1: 6.3;RT4: 1.8;SK-BR-3: 4.5" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Region enriched" "Detected in single" 12 "basal ganglia: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005131, CAB025903" Approved "Secreted to blood" 692000 "CAB025903: , HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavourable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" 0.4 0.3 0.0 0.0 1.2 0.0 0.5 0.0 0.0 3.1 0.2 0.0 0.8 0.1 4.4 13.5 0.1 0.3 0.0 0.6 0.0 0.0 63.6 0.4 0.3 0.0 0.0 0.0 11.6 0.0 0.0 0.4 14.4 0.0 0.3 0.1 0.4 0.3 0.5 0.0 0.0 0.1 1.0 0.0 0.0 0.0 2.0 0.0 0.0 1.1 0.0 0.2 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 4.8 0.9 0.0 0.0 0.1 0.6 0.0 0.3 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 6.3 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.8 0.2 0.1 0.0 4.5 0.2 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RENBP "RBP, RNBP" ENSG00000102032 "Renin binding protein" P51606 X 153935263-153944691 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 32.7;lymphoid tissue: 36.5" "Cell line enhanced" "Detected in some" "EFO-21: 12.9;HMC-1: 43.9;SK-MEL-30: 29.0;U-266/84: 25.2" "Cancer enhanced" "Detected in all" "melanoma: 57.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA000428, HPA000522" Enhanced 42000 "HPA000428: AB_1079799, HPA000522: AB_1079798" "unprognostic (3.08e-1)" "prognostic favourable (3.95e-4)" "unprognostic (1.12e-2)" "unprognostic (3.29e-1)" "unprognostic (8.83e-3)" "unprognostic (1.85e-1)" "unprognostic (5.22e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (1.15e-1)" "unprognostic (6.47e-3)" "unprognostic (1.99e-1)" "prognostic favourable (3.08e-5)" "unprognostic (2.39e-2)" "unprognostic (6.57e-2)" "unprognostic (4.25e-2)" "unprognostic (8.51e-2)" 12.7 11.1 7.8 11.2 16.8 8.6 8.4 2.3 11.5 4.2 6.2 11.3 1.1 7.4 2.1 6.0 3.0 2.5 5.7 8.7 9.4 9.1 32.7 4.6 12.8 12.1 16.9 7.4 1.2 1.6 1.8 3.4 8.1 11.6 3.6 3.0 9.6 3.4 2.0 1.4 5.2 7.5 4.5 12.7 36.5 4.4 1.4 13.5 3.0 2.9 1.1 4.4 5.7 2.9 1.1 0.6 5.3 3.1 0.3 0.9 0.7 0.0 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.9 0.0 0.0 2.5 0.0 0.0 0.0 0.5 9.8 0.0 0.8 7.6 0.0 43.9 0.3 0.0 0.0 0.0 0.0 2.8 3.4 0.0 0.2 2.0 0.1 0.1 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 29.0 0.0 3.4 0.4 0.0 0.3 0.0 0.0 4.4 25.2 1.7 0.9 4.6 3.4 2.9 2.0 5.3 0.3 1.4 0.3 1.1 0.1 0.1 0.2 0.6 0.9 0.4 4.5 0.3 3.1 0.6 0.0 0.7 7.8 16.8 2.3 11.5 9.4 9.1 16.9 7.4 11.6 13.5 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077027-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 63.9" "Cell line enhanced" "Detected in some" "MCF7: 17.6;NB-4: 11.6;SH-SY5Y: 89.7;THP-1: 26.8" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "non-classical monocyte: 6.7" "Group enriched" "Detected in many" 13 "dendritic cells: 2.1;monocytes: 6.7" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "midbrain: 95.5" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" 260000 "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavourable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 15.2 1.1 1.8 1.3 0.7 1.2 4.1 9.0 1.9 3.1 0.9 1.1 1.5 0.9 0.6 1.2 0.7 1.0 1.2 1.5 5.8 1.0 11.7 0.7 0.8 17.5 1.2 0.8 1.3 63.9 6.3 0.8 16.8 2.2 1.5 2.8 13.6 2.0 4.5 1.1 2.6 1.1 2.8 0.6 2.1 2.0 0.0 0.1 0.8 5.1 0.6 1.9 1.4 0.2 2.1 0.0 6.7 0.0 0.3 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 11.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 89.7 0.0 0.0 0.0 1.2 26.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 6.7 2.1 0.3 0.4 1.1 1.3 4.1 9.0 1.5 5.8 17.5 1.2 16.8 0.0 RETSAT FLJ20296 ENSG00000042445 "Retinol saturase" Q6NUM9 2 85342088-85354620 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 86.1" "Cell line enhanced" "Detected in many" "ASC diff: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007961, HPA046513" Uncertain Uncertain Nucleoli Nucleoli "HPA007961: AB_1079802, HPA046513: " "unprognostic (6.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (5.84e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "prognostic favourable (4.23e-4)" "unprognostic (1.89e-1)" "unprognostic (2.16e-1)" "unprognostic (3.59e-2)" "unprognostic (1.77e-2)" "unprognostic (1.59e-1)" "prognostic favourable (1.95e-10)" "unprognostic (2.73e-2)" "unprognostic (5.34e-1)" "unprognostic (8.24e-3)" "unprognostic (9.90e-2)" 65.7 24.8 7.7 9.8 9.1 0.9 35.6 5.6 9.3 7.4 46.5 12.4 12.7 49.0 6.8 12.3 16.7 5.0 17.7 7.3 7.4 5.7 20.6 51.9 7.2 5.1 10.2 7.7 5.5 11.5 13.1 3.5 5.7 8.9 10.1 22.6 10.0 12.5 7.6 24.3 14.3 86.1 7.0 12.7 4.0 18.2 9.2 10.1 3.5 27.2 13.9 9.3 9.9 9.0 3.8 5.6 5.3 10.0 6.5 9.2 4.1 15.9 9.3 5.4 12.5 64.5 12.1 7.0 11.7 14.5 7.1 10.0 6.4 11.2 5.6 9.7 9.3 13.4 7.2 20.4 7.0 6.9 5.0 2.7 7.6 15.7 15.5 5.3 6.2 15.8 28.0 9.1 12.2 11.8 2.9 13.5 13.2 3.4 3.8 2.8 1.7 11.4 2.5 10.7 7.3 12.6 9.4 2.6 4.4 9.8 18.8 31.8 8.8 0.9 9.2 8.0 4.4 7.5 6.1 7.3 6.8 2.2 9.9 6.4 5.5 0.0 5.1 2.4 7.0 5.5 9.2 3.8 5.6 8.8 5.6 2.5 3.8 4.0 5.3 6.5 10.0 4.0 5.8 4.1 7.7 9.1 5.6 9.3 7.4 5.7 10.2 7.7 8.9 10.1 REV3L "POLZ, REV3" ENSG00000009413 "REV3 like, DNA directed polymerase zeta catalytic subunit" O60673 6 111299028-111483715 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 39.4;ASC TERT1: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064853, HPA069382" Uncertain Approved Nucleoplasm Nucleoplasm "HPA064853: , HPA069382: " "unprognostic (5.54e-2)" "unprognostic (2.06e-1)" "unprognostic (5.09e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" "unprognostic (8.59e-3)" "unprognostic (4.42e-2)" "unprognostic (1.56e-2)" "unprognostic (8.09e-2)" "unprognostic (1.17e-1)" "unprognostic (6.87e-3)" "unprognostic (1.27e-1)" "unprognostic (4.34e-2)" "unprognostic (2.80e-1)" "unprognostic (1.67e-1)" "unprognostic (1.67e-1)" "unprognostic (1.03e-3)" 21.0 7.1 7.8 8.8 7.3 7.3 15.1 26.0 7.6 31.7 11.0 5.8 14.1 5.4 34.5 18.5 7.6 12.2 7.4 7.1 6.5 6.1 6.5 6.4 10.8 6.3 5.4 5.8 11.3 8.1 7.8 15.1 10.2 6.8 11.4 7.4 8.3 6.9 16.3 17.1 8.2 7.0 18.0 6.9 7.1 8.6 10.3 6.7 10.2 9.2 7.2 5.5 18.3 16.2 5.1 2.8 6.0 2.9 1.7 4.6 1.0 4.6 2.9 5.7 8.6 39.4 30.0 6.2 6.6 10.8 3.6 5.9 5.2 2.8 10.2 4.8 9.5 4.8 8.4 3.7 6.2 5.9 4.6 6.8 7.5 7.0 5.5 7.0 4.1 19.1 3.3 6.7 10.5 6.6 8.6 6.5 7.0 4.3 8.3 1.5 2.0 4.9 5.4 6.3 3.3 2.7 5.8 7.5 6.0 8.2 3.0 7.0 3.8 7.6 7.6 5.4 5.1 25.5 7.5 6.8 8.0 9.1 5.3 5.5 7.1 1.9 1.7 3.3 3.3 1.3 4.6 2.8 2.5 3.0 1.7 5.1 1.6 2.8 6.0 1.7 2.9 2.8 1.9 1.0 7.8 7.3 26.0 7.2 6.5 6.1 5.4 5.8 6.8 6.7 RFFL "CARP-2, CARP2, fring, rififylin, RNF189, RNF34L" ENSG00000092871 "Ring finger and FYVE like domain containing E3 ubiquitin protein ligase" Q8WZ73 17 35005990-35089319 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 56.8" "Cell line enhanced" "Detected in all" "HDLM-2: 40.5;Karpas-707: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB008096, HPA017910, HPA019492" Approved Approved Vesicles Vesicles "CAB008096: AB_2178607, HPA017910: AB_1856189, HPA019492: AB_1856190" "unprognostic (2.59e-1)" "unprognostic (2.87e-1)" "prognostic favourable (4.92e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.79e-1)" "unprognostic (5.73e-3)" "unprognostic (4.34e-3)" "unprognostic (2.31e-1)" "unprognostic (9.26e-3)" "unprognostic (2.39e-1)" "unprognostic (2.63e-1)" "prognostic unfavourable (2.43e-5)" "unprognostic (1.44e-1)" "unprognostic (1.97e-1)" "unprognostic (8.68e-2)" "unprognostic (1.36e-1)" 5.8 6.1 11.1 9.9 22.9 22.1 6.7 4.4 15.7 6.7 14.6 56.8 5.9 14.8 6.9 5.3 21.6 5.4 11.5 5.8 14.4 10.5 15.4 25.0 6.8 8.9 32.1 7.3 5.2 10.1 8.3 4.9 6.5 30.7 10.7 12.6 4.5 9.6 7.0 12.2 5.2 11.9 7.3 32.1 9.9 13.4 15.7 27.5 13.1 23.0 5.4 15.0 10.2 9.2 4.2 5.2 26.8 7.6 6.7 14.5 7.1 7.7 14.8 3.9 5.5 6.5 9.2 2.1 5.1 8.4 5.3 6.4 5.0 15.5 2.3 6.5 6.5 11.0 6.1 9.9 7.4 40.5 4.2 12.1 3.9 12.3 5.5 7.8 7.3 6.2 5.9 7.9 14.1 5.2 5.7 37.8 4.7 2.5 1.7 7.0 4.6 8.8 5.4 6.3 13.7 7.8 15.6 4.3 5.4 3.2 3.4 3.2 5.2 8.6 10.1 3.1 5.5 3.0 8.3 14.1 11.8 3.6 12.1 5.5 2.8 11.3 7.6 16.3 8.8 4.6 10.6 4.2 9.9 8.3 5.2 4.1 8.5 7.5 26.8 6.7 4.1 0.6 14.5 7.1 11.1 22.9 4.4 15.7 14.4 10.5 32.1 7.3 30.7 27.5 RFK "FLJ11149, RIFK" ENSG00000135002 "Riboflavin kinase" Q969G6 9 76385517-76394517 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023259, CAB033887, HPA057163" Approved Approved "Golgi apparatus" "Golgi apparatus" "CAB033887: AB_2178617, HPA023259: , HPA057163: " "unprognostic (1.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-3)" "unprognostic (8.61e-3)" "unprognostic (3.11e-1)" "unprognostic (1.39e-1)" "unprognostic (2.88e-1)" "unprognostic (1.02e-1)" "unprognostic (4.61e-2)" "unprognostic (1.22e-3)" "unprognostic (3.22e-2)" "unprognostic (1.83e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" 8.1 15.4 24.8 9.8 31.0 15.2 8.7 15.3 27.7 8.9 22.1 5.7 6.2 23.9 9.5 14.3 9.4 10.0 14.5 11.4 33.0 33.5 19.4 23.6 8.8 7.4 22.8 13.2 10.8 11.9 10.3 16.5 26.0 28.3 9.6 16.8 13.3 9.1 7.6 10.3 3.8 39.3 8.5 10.2 8.2 20.3 12.2 8.0 8.1 14.4 5.7 11.6 9.2 7.3 4.9 9.6 3.8 16.3 6.8 6.7 7.8 9.8 10.5 6.5 8.3 9.7 9.6 19.5 11.5 8.4 8.2 6.5 3.7 6.1 16.0 13.6 8.1 10.6 8.7 7.4 16.5 4.8 8.5 5.1 14.7 11.9 17.5 16.7 12.1 6.4 13.5 9.8 10.8 26.5 13.4 13.3 16.4 9.2 21.5 6.1 8.4 11.2 12.0 8.5 4.1 37.7 4.9 16.5 6.1 12.2 17.2 10.0 4.3 9.2 16.6 8.7 15.8 18.8 16.0 14.5 14.4 5.5 14.4 15.0 11.9 3.8 8.1 2.8 4.4 16.0 6.7 4.9 6.5 5.2 9.6 4.0 6.3 6.0 1.2 6.8 16.3 3.6 6.1 7.8 24.8 31.0 15.3 27.7 33.0 33.5 22.8 13.2 28.3 8.0 RFNG ENSG00000169733 "RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q9Y644 17 82047902-82051831 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011564, HPA031673" Uncertain Supported Nucleoplasm 450000 Nucleoplasm "HPA011564: AB_1079803, HPA031673: " "unprognostic (4.17e-3)" "unprognostic (7.60e-3)" "unprognostic (2.87e-3)" "unprognostic (2.49e-1)" "unprognostic (2.05e-1)" "unprognostic (2.65e-2)" "unprognostic (1.62e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "prognostic favourable (4.81e-4)" "unprognostic (1.20e-1)" "unprognostic (6.96e-3)" "unprognostic (1.77e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (4.14e-2)" 19.5 13.0 13.8 9.3 13.3 11.7 43.8 14.3 13.8 11.4 11.8 9.0 22.7 14.9 13.5 20.9 13.4 16.3 17.0 12.2 11.6 8.7 12.5 34.5 16.7 10.1 11.2 8.0 19.7 26.6 4.1 10.7 8.2 9.9 11.8 4.8 10.6 27.3 20.4 32.6 13.3 12.7 12.9 8.5 8.9 13.2 12.8 10.6 5.7 12.6 10.5 7.6 12.4 12.8 3.4 3.4 4.3 5.0 0.4 6.3 1.5 9.3 9.3 2.7 9.4 7.0 6.2 12.1 8.7 5.1 4.2 3.3 5.7 6.7 2.2 6.3 13.8 5.2 1.9 7.5 0.8 2.8 9.8 3.2 2.2 23.1 34.7 1.2 6.9 11.2 5.1 7.2 12.3 7.8 4.0 8.2 3.3 11.5 6.9 3.3 2.7 9.8 4.8 3.3 4.9 4.7 5.7 4.8 12.2 3.3 5.7 25.7 15.7 6.7 2.9 6.6 9.0 6.3 4.7 11.0 2.1 2.3 8.3 2.0 5.7 2.3 5.0 4.3 4.1 1.4 1.5 2.5 2.8 4.3 3.4 3.4 2.8 1.9 2.0 0.4 1.5 2.7 6.3 1.5 13.8 13.3 14.3 13.8 11.6 8.7 11.2 8.0 9.9 10.6 RFWD3 "FANCW, FLJ10520, RNF201" ENSG00000168411 "Ring finger and WD repeat domain 3" Q6PCD5 16 74621394-74666881 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048258, HPA075649" Approved Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA048258: , HPA075649: " "unprognostic (4.79e-2)" "unprognostic (6.45e-3)" "unprognostic (6.35e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-3)" "unprognostic (5.04e-2)" "unprognostic (3.64e-2)" "unprognostic (1.01e-1)" "unprognostic (4.03e-3)" "unprognostic (2.53e-3)" "unprognostic (1.73e-3)" "unprognostic (2.84e-1)" "unprognostic (4.31e-1)" "unprognostic (5.74e-2)" "unprognostic (3.29e-1)" 7.3 5.2 4.2 12.2 6.1 33.9 7.8 7.8 5.6 7.4 6.7 8.4 8.4 5.5 9.7 10.0 12.8 6.3 5.5 5.4 3.9 3.7 6.5 5.6 6.5 12.0 6.1 4.8 7.7 9.6 8.5 7.5 11.5 5.3 6.5 8.1 7.2 8.0 8.4 4.5 11.6 7.8 5.6 4.8 9.7 6.2 35.1 7.2 40.5 7.0 7.5 18.0 7.2 8.6 9.3 7.1 13.8 10.9 9.1 11.7 6.5 13.9 17.9 13.5 9.8 2.8 3.9 15.3 12.6 9.7 20.2 17.6 23.3 14.7 19.5 10.3 9.8 16.8 22.1 13.1 24.8 6.1 13.2 17.2 14.6 13.1 2.5 17.3 18.0 2.8 4.2 25.4 15.7 8.5 26.0 8.8 15.1 22.2 25.2 15.9 26.6 8.7 39.3 9.2 17.2 7.2 14.8 10.1 10.7 20.3 7.2 9.0 13.2 14.8 8.3 14.8 14.2 8.3 15.8 11.9 22.1 58.4 10.6 13.4 17.9 13.8 6.8 9.9 9.3 6.3 10.2 7.8 7.7 8.6 7.1 9.3 11.7 8.1 7.7 9.1 10.9 5.5 10.9 6.5 4.2 6.1 7.8 5.6 3.9 3.7 6.1 4.8 5.3 7.2 RGN "RC, SMP30" ENSG00000130988 Regucalcin Q15493 X 47078355-47093314 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 51.0;liver: 118.8" "Cell line enhanced" "Detected in some" "CACO-2: 16.1;fHDF/TERT166: 5.1;Hep G2: 24.1" "Cancer enriched" "Detected in many" 6 "liver cancer: 47.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029102, HPA029103" Enhanced Approved Nucleoplasm 47000 Nucleoplasm "HPA029102: AB_10599846, HPA029103: AB_10602097" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (5.56e-3)" "unprognostic (8.22e-3)" "unprognostic (1.32e-2)" "prognostic favourable (7.55e-4)" "unprognostic (2.60e-3)" "unprognostic (2.23e-2)" "unprognostic (8.38e-2)" "unprognostic (3.37e-2)" "unprognostic (1.14e-2)" "prognostic favourable (5.10e-10)" "unprognostic (1.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.82e-2)" "unprognostic (5.22e-2)" 2.6 51.0 6.7 0.6 6.5 0.4 1.5 8.4 6.2 2.8 1.9 6.2 2.5 4.5 2.3 6.1 1.5 1.7 2.0 4.5 6.1 4.2 17.6 118.8 4.9 0.7 5.9 4.5 7.5 12.7 6.2 2.5 4.2 5.0 4.8 1.1 8.4 7.5 6.3 3.8 0.6 4.6 4.9 4.4 1.1 2.9 1.5 5.2 0.0 6.5 1.6 0.6 2.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.3 0.6 0.0 0.0 16.1 0.0 0.0 0.8 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.1 0.8 0.1 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.7 6.5 8.4 6.2 6.1 4.2 5.9 4.5 5.0 5.2 RHBDD1 DKFZp547E052 ENSG00000144468 "Rhomboid domain containing 1" Q8TEB9 2 226835581-226999215 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013972, HPA057125" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA013972: AB_2178629, HPA057125: " "unprognostic (1.42e-1)" "unprognostic (5.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.23e-2)" "unprognostic (2.57e-1)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-1)" "unprognostic (9.40e-2)" "unprognostic (4.74e-3)" "unprognostic (4.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (9.77e-2)" "unprognostic (3.04e-2)" 12.7 14.8 10.8 16.7 16.0 11.0 13.6 8.3 13.0 13.8 14.3 21.2 9.4 11.0 20.6 16.3 13.6 15.4 12.4 14.5 11.4 9.0 13.6 16.9 12.6 17.7 17.6 11.0 18.8 20.4 18.6 17.1 10.5 13.0 15.7 12.4 13.1 14.3 15.5 13.9 13.0 17.5 15.6 16.5 17.3 13.2 25.6 14.7 56.6 17.3 8.8 18.9 18.7 15.4 19.9 16.6 9.8 15.5 8.8 12.5 8.5 5.1 4.4 4.7 7.2 14.3 14.2 0.0 12.2 9.8 6.0 6.9 3.8 8.9 4.8 10.2 12.3 6.0 0.0 12.7 11.6 12.3 4.9 7.0 2.9 3.4 15.4 7.5 4.1 13.3 18.6 11.5 25.1 4.6 18.9 12.6 6.3 9.8 12.7 3.8 0.0 4.7 5.5 0.0 7.0 4.9 6.2 4.6 3.5 6.7 2.4 9.0 6.8 8.6 6.1 2.8 6.2 10.5 3.5 14.1 6.6 34.7 8.9 9.1 8.0 8.1 11.1 9.8 6.1 15.5 9.7 17.3 9.6 7.5 13.7 19.9 10.8 8.9 2.5 8.8 10.3 16.6 12.5 8.5 10.8 16.0 8.3 13.0 11.4 9.0 17.6 11.0 13.0 14.7 RHBDD2 "NPD007, RHBDL7" ENSG00000005486 "Rhomboid domain containing 2" Q6NTF9 7 75842602-75888926 "Enzymes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045074, HPA051960" Uncertain Enhanced "Golgi apparatus" "Golgi apparatus" "HPA045074: AB_10965705, HPA051960: AB_2681673" "unprognostic (2.75e-1)" "unprognostic (3.89e-2)" "prognostic unfavourable (3.31e-5)" "unprognostic (9.79e-2)" "prognostic unfavourable (1.81e-4)" "unprognostic (2.05e-2)" "unprognostic (1.18e-2)" "unprognostic (2.37e-3)" "unprognostic (1.55e-1)" "unprognostic (2.75e-1)" "unprognostic (5.11e-2)" "unprognostic (1.87e-2)" "prognostic favourable (8.68e-6)" "unprognostic (3.73e-1)" "unprognostic (6.53e-2)" "unprognostic (1.89e-1)" "unprognostic (1.03e-1)" 12.3 50.9 44.3 9.2 64.6 12.1 12.1 14.4 68.3 17.9 11.9 18.5 43.8 18.2 8.5 31.8 14.2 22.6 12.5 14.1 48.5 69.1 18.5 21.7 22.1 8.9 33.6 29.9 12.3 23.6 81.3 56.5 10.6 37.1 15.8 9.1 23.0 22.8 57.3 6.0 14.4 12.5 7.0 16.2 9.5 15.3 15.5 10.7 9.5 34.3 4.2 7.6 10.0 9.6 11.1 13.5 76.4 14.0 13.2 27.4 12.2 7.4 24.6 11.1 22.4 6.5 4.2 4.6 4.5 17.8 10.3 8.7 13.3 20.6 2.8 4.0 8.5 12.2 7.3 5.3 3.2 8.5 14.4 2.5 15.5 12.7 17.9 4.2 23.2 9.2 13.1 11.6 5.2 6.6 5.7 18.3 8.7 49.6 8.0 23.7 10.8 14.1 5.9 7.7 21.4 16.9 13.4 14.7 29.3 16.8 35.7 17.1 23.3 8.0 6.2 16.2 13.5 10.6 9.3 15.2 5.3 4.4 16.1 6.7 19.7 76.4 14.0 17.6 18.9 13.9 16.6 11.1 21.3 16.7 13.5 10.8 18.0 15.3 24.0 13.2 7.9 11.1 27.4 12.2 44.3 64.6 14.4 68.3 48.5 69.1 33.6 29.9 37.1 10.7 RHBDF1 "C16orf8, Dist1, EGFR-RS, FLJ2235, iRhom1" ENSG00000007384 "Rhomboid 5 homolog 1" Q96CC6 16 58059-76355 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "intermediate monocyte: 1.7" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077399 Uncertain Vesicles Vesicles "HPA077399: " "unprognostic (2.62e-1)" "unprognostic (2.86e-2)" "unprognostic (4.76e-2)" "unprognostic (4.04e-2)" "unprognostic (1.51e-2)" "unprognostic (3.69e-2)" "unprognostic (5.60e-3)" "unprognostic (4.54e-3)" "unprognostic (4.51e-2)" "unprognostic (1.02e-1)" "unprognostic (7.81e-3)" "unprognostic (2.09e-1)" "prognostic unfavourable (2.49e-5)" "unprognostic (4.81e-2)" "unprognostic (1.87e-1)" "unprognostic (8.36e-2)" "unprognostic (4.22e-2)" 12.7 3.7 6.2 11.5 9.3 0.3 17.7 3.5 6.2 21.8 10.8 6.1 6.7 5.6 13.0 10.4 17.5 10.6 17.2 15.9 7.0 2.8 8.2 3.8 17.8 4.1 6.9 4.9 18.8 9.6 9.8 4.3 26.5 7.3 19.6 5.5 15.9 20.1 13.5 13.4 22.4 7.5 14.6 5.8 6.1 9.2 7.1 3.1 1.2 11.2 15.7 10.1 16.0 19.4 0.0 0.5 0.0 1.7 0.0 0.4 0.0 4.2 6.9 4.0 9.2 15.7 19.5 13.2 11.8 22.2 8.3 8.0 9.4 15.0 0.2 4.9 12.5 13.6 1.9 7.9 1.4 0.1 2.1 0.1 6.9 2.6 17.6 0.1 7.6 16.2 8.3 21.5 3.6 12.6 1.6 0.2 13.1 23.9 0.0 1.3 3.6 5.9 0.1 4.7 0.3 9.3 4.4 0.1 0.9 3.4 13.1 7.3 20.1 1.5 13.2 13.2 9.3 10.2 3.2 0.1 0.2 0.1 9.2 0.2 20.7 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 6.2 9.3 3.5 6.2 7.0 2.8 6.9 4.9 7.3 3.1 RHBDF2 "FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG" ENSG00000129667 "Rhomboid 5 homolog 2" Q6PJF5 17 76470891-76501790 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Disease mutation, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 34.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA018080 Uncertain "HPA018080: AB_2178634" "unprognostic (1.19e-1)" "unprognostic (8.71e-2)" "unprognostic (1.59e-2)" "unprognostic (5.11e-3)" "unprognostic (4.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (9.79e-3)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "prognostic unfavourable (3.96e-11)" "unprognostic (5.24e-2)" "unprognostic (2.14e-2)" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" 18.7 7.6 11.6 29.1 17.5 25.9 11.2 3.2 11.5 6.7 6.8 16.4 1.8 6.3 5.4 5.0 16.7 7.5 11.0 6.0 12.8 7.1 9.5 5.2 17.1 24.5 18.2 3.8 6.3 18.9 4.7 4.4 9.9 15.3 6.6 4.6 7.0 9.4 4.7 8.9 19.4 18.2 6.0 23.4 31.6 8.5 4.0 15.3 3.5 8.9 8.1 26.8 10.7 10.0 12.5 9.3 10.7 12.2 4.5 8.2 6.5 16.4 18.8 0.6 5.3 0.1 0.4 13.8 4.3 12.9 3.8 4.6 5.5 22.1 17.7 14.3 4.9 13.9 3.1 19.3 3.0 3.1 5.8 1.2 1.3 9.0 12.9 0.7 2.7 2.5 10.1 8.5 9.8 9.5 2.2 8.6 2.2 13.4 1.9 2.0 3.2 11.0 4.6 0.1 34.8 8.4 6.0 4.2 6.1 4.2 14.3 18.6 11.8 5.0 14.3 0.3 7.1 0.3 4.8 21.3 10.0 14.9 11.7 5.4 12.8 3.9 11.6 3.7 8.2 12.2 5.7 12.5 2.3 5.8 5.9 7.7 1.4 3.4 10.7 4.5 10.4 9.3 1.2 6.5 11.6 17.5 3.2 11.5 12.8 7.1 18.2 3.8 15.3 15.3 RHBDL1 "RHBDL, RRP" ENSG00000103269 "Rhomboid like 1" O75783 16 675666-678268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.3" "Cell line enhanced" "Detected in many" "HeLa: 9.1;MCF7: 9.6;U-266/70: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 3.4" "Group enriched" "Detected in many" 20 "B-cells: 2.2;NK-cells: 1.3;T-cells: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030359, HPA030360, HPA046593" Uncertain Approved Nucleoplasm Nucleoplasm "HPA030359: , HPA030360: , HPA046593: " "prognostic favourable (8.12e-4)" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.45e-1)" "unprognostic (2.07e-1)" "unprognostic (1.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.78e-1)" "unprognostic (6.60e-3)" "unprognostic (2.74e-2)" "unprognostic (3.97e-2)" "unprognostic (5.63e-3)" "unprognostic (5.89e-2)" "unprognostic (1.27e-1)" "unprognostic (8.30e-3)" "unprognostic (1.49e-2)" 1.7 6.3 10.0 1.1 8.3 2.3 0.7 21.3 14.5 1.3 2.2 1.3 2.2 5.8 1.3 1.7 1.1 1.0 1.2 2.4 8.4 9.9 3.9 1.2 0.8 1.1 5.5 7.2 0.9 6.2 2.2 4.4 1.1 4.6 1.5 1.1 1.5 6.1 2.6 0.8 3.1 5.9 0.7 2.2 0.6 4.5 2.2 1.9 0.7 0.6 0.6 0.5 0.8 0.5 2.2 0.1 0.0 0.0 1.3 3.4 0.7 1.7 2.3 1.3 2.0 1.0 2.6 6.7 0.8 1.2 0.4 0.1 4.7 1.3 0.7 1.6 0.5 1.2 0.1 0.4 0.0 1.7 8.5 1.0 9.1 1.9 0.9 1.7 1.3 1.8 3.2 0.3 0.0 0.1 1.3 1.3 0.1 9.6 0.4 4.6 1.2 0.7 8.1 1.2 1.7 0.1 1.6 1.6 2.2 1.0 0.5 2.2 3.5 4.8 0.5 2.8 2.6 0.9 0.6 11.7 1.6 2.3 1.0 3.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 0.3 0.0 0.5 0.5 0.2 0.0 1.3 0.0 0.1 1.2 0.7 10.0 8.3 21.3 14.5 8.4 9.9 5.5 7.2 4.6 1.9 RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941799 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 26.0;HaCaT: 13.5;RT4: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA043807 Approved "HPA043807: AB_10961118" "unprognostic (3.34e-2)" "unprognostic (2.96e-1)" "unprognostic (4.57e-2)" "unprognostic (2.56e-1)" "unprognostic (7.26e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (5.81e-2)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" "unprognostic (4.07e-3)" "unprognostic (1.23e-1)" "unprognostic (7.47e-9)" "unprognostic (1.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.12e-2)" "unprognostic (4.20e-2)" 1.4 0.0 2.9 6.7 2.7 0.0 1.5 0.4 4.0 5.5 14.9 1.7 0.4 0.7 1.9 0.7 18.9 0.7 6.9 4.9 4.2 2.1 0.5 0.4 2.1 1.5 4.9 0.7 1.2 2.4 0.0 0.4 1.0 1.6 3.1 14.7 0.8 8.2 0.4 0.4 13.4 0.9 0.9 7.9 0.6 12.3 8.4 0.4 1.3 0.4 12.2 16.4 6.9 8.2 1.7 2.1 5.3 1.7 0.9 0.9 0.7 8.0 3.2 0.2 0.1 0.1 1.0 0.9 0.4 0.1 0.6 0.0 0.5 26.0 0.2 1.9 3.7 13.5 0.0 4.8 0.3 0.1 0.1 0.1 2.0 1.7 0.5 0.0 0.3 0.6 0.6 3.9 0.0 0.8 0.0 0.2 0.5 0.0 0.0 0.1 0.2 0.7 0.1 0.1 0.0 0.0 26.1 0.2 0.1 2.8 6.6 0.2 3.4 0.2 0.5 2.9 0.3 0.2 0.2 0.2 0.3 0.3 2.5 0.4 0.1 3.6 1.7 1.1 0.8 1.1 0.4 1.7 0.6 0.5 1.9 1.1 0.7 0.7 5.3 0.9 0.7 2.1 0.9 0.7 2.9 2.7 0.4 1.5 4.2 2.1 4.9 0.7 1.6 0.4 RHBDL3 "RHBDL4, VRHO" ENSG00000141314 "Rhomboid like 3" P58872 17 32266176-32324661 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7" "Cell line enhanced" "Detected in some" "A549: 5.9;AF22: 5.9;AN3-CA: 4.7;HDLM-2: 8.1;NTERA-2: 8.8;U-2 OS: 6.2" "Cancer enhanced" "Detected in some" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059607 Uncertain "HPA059607: " "unprognostic (7.70e-2)" "unprognostic (3.71e-2)" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.91e-1)" "unprognostic (2.83e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "unprognostic (2.18e-3)" "unprognostic (2.11e-1)" "unprognostic (1.23e-1)" "unprognostic (8.87e-2)" 1.0 8.2 6.8 1.2 7.4 0.7 1.1 11.3 23.7 1.4 1.2 2.9 3.3 0.9 2.0 1.9 1.3 4.4 0.9 9.7 10.1 6.6 0.8 0.6 0.7 0.7 9.1 4.6 3.4 1.1 0.6 1.9 1.0 6.7 2.1 1.4 3.9 1.0 5.6 0.6 0.9 0.9 1.8 3.6 0.6 0.9 2.5 4.0 0.0 0.6 0.0 0.8 1.9 1.1 0.8 0.0 0.0 0.0 0.0 0.3 0.3 0.0 5.9 5.9 4.7 0.9 0.0 0.1 0.3 0.6 1.9 2.0 0.1 0.0 0.0 0.4 0.7 0.1 1.6 0.0 0.5 8.1 2.3 1.0 4.0 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.5 0.1 0.2 0.0 8.8 0.0 1.0 0.0 0.0 0.0 3.2 0.1 1.6 0.8 0.1 0.1 0.4 0.1 0.0 0.0 6.2 0.3 3.0 0.0 0.0 0.0 0.3 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 6.8 7.4 11.3 15.6 10.1 6.6 9.1 4.6 6.7 4.0 RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117241 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "kidney: 81.4;liver: 248.6" "Low cell line specificity" "Detected in all" "Cancer enhanced" "Detected in all" "liver cancer: 162.2" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced 5700000 "HPA022856: AB_1858253, HPA023489: AB_1858252" "unprognostic (1.67e-2)" "unprognostic (3.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "prognostic favourable (9.61e-6)" "unprognostic (6.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-2)" "unprognostic (1.51e-2)" 8.3 9.4 16.8 2.5 18.8 1.6 4.2 5.6 11.6 2.6 4.7 4.5 2.7 5.8 2.1 4.8 2.8 2.2 4.3 5.2 11.7 12.5 81.4 248.6 2.2 2.1 19.1 9.5 4.6 5.2 3.5 1.8 2.4 11.8 4.0 4.8 2.3 3.2 2.7 6.8 2.3 4.2 2.5 7.9 1.8 4.6 3.3 9.5 0.6 3.2 3.5 2.6 3.2 1.8 12.1 10.0 5.0 8.3 8.4 12.8 7.1 17.1 14.9 12.1 14.7 27.3 21.3 13.2 15.9 11.2 10.6 12.8 20.2 11.5 24.4 20.4 11.6 12.2 26.4 22.5 21.5 8.5 11.4 17.7 10.1 21.6 12.5 6.5 2.8 18.4 7.8 14.9 16.4 13.7 31.5 5.3 14.2 22.3 13.8 17.8 19.0 27.3 16.0 8.8 7.0 25.6 12.4 13.1 6.5 10.1 7.0 11.0 17.9 8.6 8.3 8.3 5.2 13.9 6.3 12.7 17.4 12.0 14.4 13.8 5.3 0.1 8.3 5.0 6.5 7.0 8.3 12.1 9.4 9.5 10.0 9.5 12.2 12.8 1.5 8.4 7.0 7.6 12.3 7.1 16.8 18.8 5.6 11.6 11.7 12.5 19.1 9.5 11.8 9.5 RIMKLA "FAM80A, MGC47816, NAAGS-II, RP11-157D18.1" ENSG00000177181 "Ribosomal modification protein rimK like family member A" Q8IXN7 1 42380795-42422578 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell line enhanced" "Detected in some" "AN3-CA: 7.8;Karpas-707: 9.0;SCLC-21H: 11.8;U-266/70: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027826 Uncertain Uncertain "Nucleoli fibrillar center" "Nucleoli fibrillar center" "HPA027826: AB_10603992" "unprognostic (4.04e-2)" "unprognostic (1.61e-1)" "unprognostic (3.68e-3)" "unprognostic (9.84e-2)" "unprognostic (2.49e-2)" "unprognostic (1.06e-1)" "unprognostic (2.63e-3)" "prognostic favourable (1.43e-4)" "unprognostic (8.89e-2)" "unprognostic (3.76e-1)" "unprognostic (9.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.22e-3)" "unprognostic (3.99e-2)" "unprognostic (7.07e-2)" "unprognostic (1.63e-2)" "unprognostic (3.44e-1)" 0.9 1.2 6.2 1.5 10.4 0.8 1.3 7.8 18.4 1.0 7.9 1.7 0.0 1.4 1.0 0.8 1.0 0.9 1.8 8.5 7.5 5.9 2.5 0.7 5.4 0.8 7.9 8.5 0.7 2.5 6.6 2.0 1.3 20.1 2.2 9.0 3.3 1.1 1.2 1.4 1.1 1.3 2.4 3.6 1.1 2.1 2.3 1.2 0.0 2.2 0.0 0.8 1.1 0.4 0.3 1.6 1.3 0.2 0.4 2.0 0.1 0.0 0.8 0.1 7.8 0.1 0.0 1.4 0.0 0.0 0.2 0.5 0.4 0.2 0.0 1.6 0.0 0.0 4.6 0.0 0.4 4.1 3.0 0.3 0.1 1.3 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.3 2.1 0.0 3.9 5.5 0.0 0.3 0.4 0.6 2.0 11.8 5.0 0.4 0.3 0.1 0.4 2.0 0.0 0.0 0.4 0.0 0.7 8.2 4.6 5.4 0.1 0.0 0.0 1.1 0.2 1.3 0.2 0.2 2.0 0.2 0.1 1.0 0.0 0.3 0.1 0.2 1.0 0.4 0.1 1.6 0.1 0.1 6.2 10.4 7.8 18.4 7.5 5.9 7.9 8.5 20.1 1.2 RIMKLB "FAM80B, KIAA1238, NAAGS, NAAGS-I" ENSG00000166532 "Ribosomal modification protein rimK like family member B" Q9ULI2 12 8681600-8783095 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 53.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059552 Approved "Nucleoplasm,Centriolar satellite" "Nucleoplasm, Centriolar satellite" "HPA059552: " "unprognostic (5.29e-3)" "unprognostic (2.26e-2)" "unprognostic (1.89e-5)" "unprognostic (2.40e-2)" "unprognostic (2.30e-1)" "unprognostic (3.35e-2)" "unprognostic (6.56e-2)" "unprognostic (8.52e-2)" "unprognostic (8.67e-3)" "unprognostic (1.76e-1)" "unprognostic (3.25e-1)" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (2.16e-2)" "unprognostic (3.02e-1)" "unprognostic (3.74e-1)" "unprognostic (3.99e-1)" 22.5 10.7 15.9 10.7 19.2 15.8 20.1 23.3 21.2 18.1 17.6 16.4 11.2 5.1 35.9 18.2 10.4 25.4 12.5 10.7 17.6 12.8 9.2 3.2 13.9 7.6 10.2 19.0 22.7 7.3 36.2 10.1 21.2 19.9 11.7 6.5 18.0 9.0 13.5 9.5 8.8 8.7 25.5 14.0 11.5 7.7 27.8 12.1 13.6 15.6 4.8 6.4 11.8 18.4 4.0 1.3 5.3 2.9 2.8 3.9 2.5 1.2 7.2 16.6 17.7 2.3 2.0 23.8 6.9 3.4 5.9 4.0 0.6 7.6 10.5 6.6 4.5 2.7 8.4 9.3 6.5 0.1 5.1 4.8 20.3 0.0 2.6 1.4 4.9 4.4 4.2 5.5 9.7 7.6 6.6 0.0 3.6 4.3 9.6 0.6 19.6 0.4 15.1 22.7 0.0 9.0 3.7 0.5 10.9 7.6 9.9 6.8 2.1 4.8 14.3 6.2 20.7 3.2 2.2 0.1 0.0 53.0 5.4 0.9 4.3 5.3 2.9 1.2 2.4 1.1 3.0 2.2 2.4 3.5 1.2 4.0 3.9 1.5 0.7 2.8 1.4 1.3 0.1 2.5 15.9 19.2 23.3 19.5 17.6 12.8 10.2 19.0 19.9 12.1 RING1 RNF1 ENSG00000204227 "Ring finger protein 1" Q06587 6 33208495-33212722 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008701 Supported Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA008701: AB_1079814" "unprognostic (2.12e-3)" "unprognostic (7.98e-2)" "unprognostic (3.77e-2)" "unprognostic (1.37e-1)" "unprognostic (3.91e-2)" "unprognostic (3.21e-1)" "unprognostic (1.53e-1)" "unprognostic (4.75e-2)" "unprognostic (7.76e-2)" "unprognostic (1.26e-2)" "unprognostic (3.70e-2)" "unprognostic (1.62e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (1.55e-1)" "unprognostic (2.13e-1)" "unprognostic (9.88e-2)" 26.7 22.6 17.8 15.9 21.3 12.0 14.6 27.6 24.2 22.2 17.6 22.0 21.0 18.2 31.9 17.3 14.5 18.8 21.4 14.4 17.3 18.2 19.3 21.6 16.8 14.5 24.0 15.4 25.0 18.3 24.0 34.0 14.9 17.0 21.8 7.6 20.0 19.0 20.5 18.0 21.7 19.5 22.9 18.5 23.2 24.1 16.9 20.8 25.5 29.3 13.1 14.3 13.9 17.1 1.2 2.2 0.8 1.5 0.2 2.2 0.2 4.2 3.5 4.2 4.0 4.2 1.4 9.7 11.1 6.8 4.5 4.6 3.8 3.1 6.9 4.6 4.4 7.6 3.6 3.3 3.2 8.5 2.9 8.3 5.8 7.1 9.6 4.7 6.8 0.0 3.4 4.0 7.5 1.6 11.9 5.3 4.7 0.0 0.3 3.7 1.9 4.6 4.5 6.9 7.6 5.0 3.7 8.3 5.2 4.0 4.3 11.5 4.9 8.3 2.3 5.0 3.8 0.0 9.1 6.0 6.2 6.6 3.7 4.3 3.1 0.0 1.5 0.8 2.2 0.4 0.4 1.1 0.7 1.0 0.7 1.2 1.7 0.9 0.3 0.2 0.5 2.2 0.4 0.2 17.8 21.3 27.6 24.2 17.3 18.2 24.0 15.4 17.0 20.8 RIOK1 "AD034, bA288G3.1, FLJ30006, RRP10" ENSG00000124784 "RIO kinase 1" Q9BRS2 6 7389496-7418037 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017866, HPA051446" Enhanced Approved "Nucleoli,Nuclear speckles,Cytosol" "Nucleoli, Nuclear speckles" Cytosol "HPA017866: , HPA051446: " "unprognostic (2.33e-2)" "unprognostic (1.24e-1)" "unprognostic (2.38e-1)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "prognostic unfavourable (3.41e-5)" "unprognostic (2.23e-1)" "prognostic unfavourable (4.43e-4)" "unprognostic (3.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "prognostic unfavourable (5.85e-5)" "unprognostic (2.33e-1)" "unprognostic (2.09e-1)" "unprognostic (6.12e-3)" "unprognostic (2.59e-2)" 13.8 10.6 7.7 13.2 13.0 17.5 13.1 12.2 13.5 12.7 11.6 7.3 4.0 7.3 15.4 6.0 15.6 12.3 8.5 11.8 8.0 8.1 8.7 11.7 10.1 14.2 11.6 9.4 13.8 15.3 7.7 17.8 13.9 13.3 10.7 9.6 7.2 10.2 10.3 18.8 12.5 9.9 15.5 9.4 14.4 10.3 21.3 9.2 19.2 10.1 14.7 16.8 10.9 12.6 15.4 14.9 7.7 11.1 18.6 15.0 8.2 7.5 4.4 7.1 16.7 11.1 9.1 10.9 9.5 6.4 8.9 7.4 12.8 3.9 19.7 16.9 7.7 7.7 17.9 7.6 11.4 13.0 19.3 10.5 7.1 13.7 9.4 30.2 13.8 6.7 10.6 9.6 19.8 7.8 26.8 4.6 8.3 9.9 20.5 14.3 15.3 10.4 15.8 9.3 21.4 5.0 7.4 23.7 11.7 8.0 4.8 13.8 7.3 10.0 7.8 9.8 7.4 6.4 14.3 6.4 12.1 29.3 3.0 15.6 14.9 7.7 8.5 5.9 11.5 11.1 13.8 15.2 11.9 12.1 14.9 15.4 13.7 15.0 1.7 18.6 9.7 12.4 11.3 8.2 7.7 13.0 12.2 13.5 8.0 8.1 11.6 9.4 13.3 9.2 RIOK2 FLJ11159 ENSG00000058729 "RIO kinase 2" Q9BVS4 5 97160867-97183260 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA005681 Uncertain Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA005681: AB_1856286" "unprognostic (6.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-2)" "unprognostic (8.04e-2)" "unprognostic (1.38e-1)" "unprognostic (4.51e-2)" "unprognostic (2.71e-3)" "unprognostic (3.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.11e-1)" "unprognostic (8.76e-2)" "unprognostic (6.63e-2)" "unprognostic (1.26e-3)" "unprognostic (3.60e-1)" "unprognostic (9.98e-2)" "unprognostic (1.43e-2)" "unprognostic (1.39e-2)" 22.2 20.1 14.8 17.1 17.5 24.4 19.7 26.3 18.6 19.1 17.0 8.9 14.0 17.3 17.5 17.1 17.0 15.0 10.7 19.6 15.7 13.4 21.0 23.6 13.3 17.6 20.0 11.1 20.7 21.5 15.1 37.5 15.8 19.7 19.5 17.3 10.3 18.7 16.6 24.9 13.3 20.2 16.3 20.7 22.5 16.4 14.8 18.6 25.8 21.7 20.7 17.4 20.7 21.0 15.2 17.8 9.4 18.7 17.8 24.1 13.5 8.8 10.4 9.7 18.8 12.8 14.0 15.5 22.3 13.8 15.8 21.0 14.2 15.6 19.6 25.4 10.0 10.5 16.5 13.0 21.7 13.8 9.1 9.8 20.1 19.8 11.5 18.6 13.8 9.2 10.2 19.3 19.6 12.8 14.8 12.7 18.1 14.8 21.7 22.2 11.5 11.2 24.5 18.9 28.8 12.4 8.1 12.1 9.0 13.5 14.0 15.3 14.7 17.7 13.7 20.3 14.1 16.1 24.2 12.5 16.2 44.0 12.1 19.1 18.4 7.0 16.0 9.4 16.3 18.7 22.3 15.2 20.7 17.8 17.8 11.0 22.5 24.1 3.2 17.8 13.4 17.8 18.5 13.5 14.8 17.5 26.3 18.6 15.7 13.4 20.0 11.1 19.7 18.6 RIOK3 SUDD ENSG00000101782 "RIO kinase 3" O14730 18 23452823-23486603 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001620, HPA024184" Approved Approved "Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" "Plasma membrane, Cytosol" "Golgi apparatus, Centriolar satellite" "HPA001620: AB_1079815, HPA024184: AB_1856289" "unprognostic (7.99e-2)" "unprognostic (1.71e-2)" "unprognostic (2.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.48e-2)" "unprognostic (8.98e-3)" "unprognostic (1.01e-1)" "unprognostic (5.10e-2)" "unprognostic (4.20e-1)" "prognostic unfavourable (4.10e-4)" "prognostic unfavourable (5.80e-4)" "unprognostic (3.90e-2)" "unprognostic (1.46e-1)" "unprognostic (5.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.71e-2)" 10.1 8.7 6.9 11.7 7.7 52.4 10.9 8.9 10.1 14.7 21.4 8.5 5.9 15.6 8.8 9.3 41.0 7.8 10.7 11.5 6.1 5.5 10.5 19.9 10.1 10.7 9.1 6.2 7.6 10.7 7.5 11.6 21.4 11.6 6.8 14.7 6.0 14.9 7.0 40.0 13.3 36.5 15.2 10.5 8.9 12.9 22.7 7.6 11.1 7.3 16.0 16.5 13.7 21.5 11.7 11.0 21.7 21.5 8.3 11.2 10.0 14.7 5.8 6.0 7.8 11.0 12.3 10.9 14.8 10.9 10.5 10.1 6.6 15.9 10.2 19.4 16.4 19.3 10.2 16.8 16.2 10.1 4.2 9.5 10.8 8.3 27.5 26.7 8.3 14.7 32.0 18.6 25.8 14.5 13.7 12.9 15.7 7.8 9.2 4.4 5.6 11.6 10.4 12.6 12.4 12.0 19.3 14.0 10.1 18.9 8.6 10.8 7.6 14.5 22.9 17.3 4.3 7.6 9.6 23.2 19.6 15.2 10.2 12.4 12.9 21.7 13.5 8.0 9.1 19.6 6.9 8.2 7.6 7.9 11.0 11.7 6.1 6.9 9.3 8.3 21.5 5.1 11.2 10.0 6.9 7.7 8.9 10.1 6.1 5.5 9.1 6.2 11.6 7.6 RIOX1 "C14orf169, FLJ21802, JMJD9, MAPJD, NO66" ENSG00000170468 "Ribosomal oxygenase 1" Q9H6W3 14 73490964-73493392 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003730 Supported Nucleoli Nucleoli "HPA003730: " "unprognostic (4.70e-3)" "unprognostic (1.94e-2)" "unprognostic (2.45e-1)" "unprognostic (2.32e-1)" "unprognostic (1.84e-3)" "unprognostic (1.73e-1)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (6.51e-2)" "unprognostic (5.36e-2)" "unprognostic (1.35e-3)" "unprognostic (4.55e-2)" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (1.67e-1)" "unprognostic (7.97e-3)" "unprognostic (8.62e-2)" 3.9 2.4 4.3 5.2 5.6 8.0 4.0 7.6 8.0 5.3 4.1 6.7 3.6 4.1 4.5 5.7 3.9 4.7 3.3 5.3 3.4 4.1 5.1 4.1 8.4 5.8 4.9 4.5 6.1 5.2 3.2 2.8 4.6 4.0 4.1 4.7 5.0 5.0 2.8 4.0 3.4 4.8 2.1 5.0 3.9 10.5 5.2 17.3 4.5 3.6 7.5 3.7 4.4 3.5 5.2 5.1 3.8 4.9 7.4 1.3 10.3 9.4 6.1 9.4 7.9 4.5 11.7 7.1 5.2 7.3 6.6 8.1 5.3 17.7 5.2 6.1 12.3 11.6 7.0 6.1 11.2 12.8 11.1 5.6 5.3 4.4 0.0 14.9 4.8 6.5 7.0 3.2 6.6 8.0 6.6 6.5 16.3 19.3 12.6 6.7 15.9 15.4 9.5 5.3 7.2 7.8 12.7 9.2 11.8 21.2 7.5 21.1 11.1 9.4 0.0 12.2 6.3 0.0 9.1 9.7 6.2 3.2 9.2 7.2 0.2 2.2 5.1 6.4 3.8 7.4 3.5 6.5 5.1 3.0 2.7 6.0 4.4 0.9 4.9 2.3 5.2 2.8 1.3 RIPK1 RIP ENSG00000137275 "Receptor interacting serine/threonine kinase 1" Q13546 6 3063991-3115187 "Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010302, HPA015257" Supported Enhanced "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB010302: AB_2178118, HPA015257: AB_1856294" "unprognostic (1.24e-1)" "unprognostic (6.83e-2)" "unprognostic (1.87e-1)" "unprognostic (7.75e-2)" "unprognostic (6.08e-2)" "unprognostic (1.01e-2)" "unprognostic (1.26e-2)" "unprognostic (1.96e-1)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (5.00e-2)" "unprognostic (3.29e-1)" "unprognostic (9.65e-3)" "unprognostic (3.44e-1)" "unprognostic (9.01e-2)" "unprognostic (1.38e-2)" "prognostic favourable (6.71e-4)" 24.5 12.0 6.9 15.7 12.4 10.5 28.0 11.9 11.0 16.4 18.9 9.6 22.9 14.5 16.8 17.7 17.1 13.5 17.9 12.3 7.5 6.8 18.5 36.7 16.7 19.8 11.8 6.6 13.2 19.9 14.4 17.9 24.4 10.2 17.8 16.6 10.9 21.1 18.7 11.4 18.9 24.8 21.3 6.9 19.4 15.8 9.0 9.4 18.6 18.5 15.2 19.2 15.0 20.4 4.1 3.2 6.6 3.9 6.6 7.6 2.1 9.5 6.9 10.4 10.7 22.2 14.2 5.7 15.1 20.5 16.0 18.4 9.3 6.6 9.0 14.6 21.6 11.0 12.9 12.4 17.5 18.6 7.0 11.5 4.5 6.7 12.5 10.0 14.8 19.2 11.1 14.8 10.7 13.8 13.0 5.2 15.4 12.4 6.9 10.9 6.5 8.6 8.4 7.7 10.1 14.3 19.2 9.0 8.8 9.9 6.3 16.7 11.4 7.1 16.7 17.5 9.4 6.6 11.1 8.0 10.3 9.6 7.3 5.5 19.4 1.1 3.0 6.4 6.1 3.7 4.9 2.0 4.9 7.6 3.2 4.1 4.1 5.4 6.6 6.6 3.9 2.9 5.7 2.1 6.9 12.4 11.9 11.0 7.5 6.8 11.8 6.6 10.2 9.4 RIPK2 "CARD3, CARDIAK, RICK, RIP2" ENSG00000104312 "Receptor interacting serine/threonine kinase 2" O43353 8 89757747-89791063 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015273, HPA016499" Approved Enhanced Cytosol Cytosol "HPA015273: AB_1856299, HPA016499: AB_1856300" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (1.67e-1)" "unprognostic (6.20e-2)" "unprognostic (1.43e-3)" "prognostic unfavourable (6.33e-5)" "unprognostic (2.06e-1)" "unprognostic (7.80e-2)" "prognostic unfavourable (5.00e-6)" "unprognostic (6.39e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.84e-2)" "unprognostic (5.08e-2)" "unprognostic (1.05e-2)" "prognostic favourable (8.05e-4)" 12.0 5.5 9.3 11.2 7.9 13.6 10.0 3.0 9.3 9.7 7.9 10.6 5.2 3.5 10.9 7.8 8.3 7.0 17.3 11.6 9.2 8.6 7.7 10.4 18.7 10.9 11.8 5.8 8.9 13.2 14.7 7.3 20.8 9.1 10.7 5.6 4.6 10.2 5.8 3.1 10.4 6.9 10.4 16.5 14.2 8.3 5.6 11.5 5.1 8.5 4.9 11.8 15.0 7.6 7.5 6.9 19.4 11.2 3.8 5.5 4.3 10.1 3.5 1.8 2.6 4.4 6.1 3.3 11.3 19.3 6.0 7.8 3.1 5.3 7.9 17.6 6.3 2.4 4.8 3.7 11.1 5.6 4.9 6.6 1.7 3.1 12.4 2.4 3.2 4.9 3.0 8.5 27.7 6.3 3.2 2.6 5.5 2.1 0.0 5.0 1.0 8.4 1.7 2.5 3.8 14.0 4.6 0.3 2.0 2.7 7.1 5.3 6.8 3.0 5.6 3.7 3.5 6.2 5.2 5.2 2.3 4.7 9.0 0.2 2.4 8.8 5.7 19.4 3.6 10.6 4.1 7.5 5.5 4.7 6.9 4.3 5.2 5.5 4.5 3.8 11.2 2.3 1.2 4.3 9.3 7.9 3.0 7.4 9.2 8.6 11.8 5.8 9.1 11.5 RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767106 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 16.3;HaCaT: 24.0;hTCEpi: 16.2;PC-3: 13.4;RPTEC TERT1: 14.5;RT4: 15.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 9 "naive CD4 T-cell: 1.5;neutrophil: 2.2" "Group enriched" "Detected in many" 17 "granulocytes: 2.2;T-cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA030942 Enhanced "HPA030942: " "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavourable (6.22e-5)" "prognostic unfavourable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favourable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" 1.0 0.2 0.2 0.8 0.2 0.1 3.3 0.2 0.2 6.7 9.4 0.3 12.0 6.8 1.7 6.5 42.1 4.2 17.1 1.1 0.4 0.2 10.8 17.3 5.4 0.4 0.2 0.1 1.8 14.4 4.7 6.8 2.8 1.1 10.6 1.3 4.8 10.2 14.8 0.2 11.7 11.6 2.0 0.3 0.2 11.2 2.7 0.0 8.1 13.6 12.3 26.6 5.2 11.0 0.0 0.0 2.2 0.1 0.0 1.5 0.2 7.0 4.5 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 0.1 11.7 16.3 0.0 6.9 1.4 24.0 0.3 9.7 0.0 0.0 4.8 0.0 3.3 4.3 0.0 0.0 0.0 0.0 16.2 0.1 2.2 0.0 0.0 0.0 0.0 5.1 0.9 0.0 0.4 13.4 0.0 0.0 1.1 14.5 15.5 2.3 0.1 7.8 8.0 7.3 4.9 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 2.1 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.1 2.2 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.4 0.2 0.2 0.1 1.1 0.0 RLIM "MGC15161, NY-REN-43, RNF12" ENSG00000131263 "Ring finger protein, LIM domain interacting" Q9NVW2 X 74585217-74614617 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018895 Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA018895: AB_1856323" "unprognostic (1.17e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-1)" "unprognostic (1.31e-3)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (8.98e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (4.91e-2)" "unprognostic (2.25e-1)" "unprognostic (3.82e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (6.04e-4)" "unprognostic (1.20e-1)" 11.8 14.3 17.5 10.6 25.6 37.4 12.4 12.6 20.5 12.2 7.4 8.3 5.6 6.4 10.6 8.0 10.2 9.5 10.7 10.5 17.1 16.6 11.6 9.7 13.8 9.2 12.4 13.7 12.4 9.7 19.5 18.5 10.5 28.6 11.9 7.6 5.2 8.9 8.7 11.2 10.2 7.1 10.1 13.9 9.8 8.4 6.9 12.4 9.7 13.0 6.2 10.1 10.5 9.3 3.5 4.8 16.3 7.4 5.2 4.6 3.0 13.5 13.8 13.4 11.2 13.5 14.3 13.2 13.1 15.2 11.7 14.5 10.7 14.2 7.3 15.3 16.4 11.8 26.9 15.7 18.0 6.6 14.2 12.8 24.3 6.5 12.0 19.3 22.9 13.8 9.9 16.7 28.7 13.6 11.1 13.3 15.4 10.3 14.3 10.9 20.6 13.3 13.7 28.4 12.3 10.9 16.2 9.9 11.5 24.5 11.9 15.2 6.7 15.2 18.0 14.2 13.8 14.5 11.4 7.1 13.6 11.7 15.5 19.6 13.8 16.3 5.9 5.6 3.2 7.4 3.3 3.0 4.1 4.0 4.8 3.5 4.5 4.1 11.4 5.2 5.4 2.6 4.6 3.0 17.5 25.6 12.6 20.5 17.1 16.6 12.4 13.7 28.6 12.4 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20803278 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "pancreas: 809.6" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 73.2;RT4: 28.7;TIME: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 8.0;myeloid DC: 16.1" "Group enriched" "Detected in many" 9 "dendritic cells: 16.1;monocytes: 8.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" 1500000000 Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 79.2 48.4 28.7 12.0 38.5 1.6 59.7 4.0 32.2 21.3 33.7 57.8 63.6 16.8 13.6 49.1 19.3 24.3 37.5 70.3 41.2 21.6 33.8 8.6 94.3 23.5 39.0 16.0 19.2 809.6 6.7 4.1 79.0 25.1 23.0 39.8 106.4 15.9 35.6 31.7 10.8 20.6 26.6 52.3 34.5 87.9 86.5 27.1 7.8 11.2 14.3 7.2 29.0 10.9 0.0 16.1 1.3 8.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 73.2 7.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.3 0.0 28.7 0.3 0.3 0.0 0.2 0.0 0.0 0.0 38.0 0.0 0.6 0.4 0.0 0.1 0.0 0.0 1.0 0.0 1.0 1.3 8.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.1 0.0 0.0 3.7 0.0 2.0 28.7 38.5 4.0 32.2 41.2 21.6 39.0 16.0 25.1 27.1 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955452-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "blood: 137.2;bone marrow: 236.7" "Group enriched" "Detected in some" 318 "HL-60: 53.6;NB-4: 53.6;THP-1: 143.6;U-937: 130.2" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 37.8;eosinophil: 137.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 137.2" HPA044983 Enhanced "Secreted to blood" 300000000 "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavourable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 2.7 3.2 4.8 2.0 9.3 236.7 0.5 0.9 3.7 0.9 0.6 1.4 0.1 0.5 0.7 0.5 0.5 3.2 0.9 3.7 3.9 1.8 1.2 1.3 6.6 7.2 4.7 0.1 0.5 2.5 0.5 0.6 0.8 4.9 0.5 0.6 0.1 0.7 0.5 0.9 0.9 0.6 2.1 10.5 19.4 0.9 0.6 3.7 0.1 0.5 0.1 0.6 1.4 0.3 0.0 20.0 137.2 11.5 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 53.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 143.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 130.2 0.0 37.8 11.5 137.2 0.0 2.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 1.0 0.0 0.2 0.2 0.0 3.3 4.8 9.3 0.9 3.7 3.9 1.8 4.7 0.1 4.9 3.7 RNASEH1 ENSG00000171865 "Ribonuclease H1" O60930 2 3544793-3558616 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease mutation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA043037 Uncertain "Intracellular and membrane" "HPA043037: " "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "unprognostic (8.81e-3)" "unprognostic (4.32e-3)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "prognostic unfavourable (7.83e-6)" "unprognostic (9.43e-2)" "unprognostic (8.46e-3)" "unprognostic (6.38e-2)" "unprognostic (2.29e-3)" "unprognostic (2.67e-1)" "unprognostic (4.06e-2)" "unprognostic (2.34e-2)" "unprognostic (2.11e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-3)" 16.6 12.8 10.1 14.5 15.4 14.7 16.1 11.0 13.1 9.7 12.1 11.4 10.8 11.8 13.3 14.0 14.1 10.0 11.0 18.5 13.1 10.3 10.9 17.0 11.2 18.3 12.9 11.4 10.1 15.1 10.5 10.8 11.5 12.3 11.2 12.6 9.5 11.2 16.0 35.3 11.3 11.3 17.7 11.9 12.4 11.8 13.8 12.5 10.9 10.1 10.3 14.5 12.8 11.8 16.6 15.9 7.4 12.8 17.2 14.6 10.8 8.9 21.0 7.3 12.3 7.6 7.9 16.2 14.8 12.8 12.6 10.2 16.0 10.9 17.3 16.0 13.2 9.9 12.1 12.0 10.1 12.9 7.9 14.9 12.5 26.8 14.5 19.5 14.1 7.0 10.1 13.6 16.1 11.1 20.4 17.4 12.9 17.8 11.5 10.9 14.1 15.7 14.1 11.9 18.1 7.6 15.9 12.2 16.0 12.5 8.8 12.4 7.4 7.5 11.4 16.7 11.5 13.3 20.5 25.7 34.7 28.9 15.6 14.7 21.8 2.8 11.5 7.4 14.5 12.8 14.6 16.6 12.7 13.6 14.2 13.8 12.9 12.5 3.2 17.2 11.1 15.9 11.2 10.8 10.1 15.4 11.0 13.1 13.1 10.3 12.9 11.4 12.3 12.5 RNASEH2A "AGS4, RNASEHI, RNHIA, RNHL" ENSG00000104889 "Ribonuclease H2 subunit A" O75792 19 12806556-12815201 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 44.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042692 Enhanced Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA042692: AB_10793981" "unprognostic (6.74e-2)" "prognostic favourable (1.18e-4)" "prognostic favourable (6.18e-4)" "unprognostic (2.24e-1)" "unprognostic (2.62e-1)" "unprognostic (5.13e-2)" "prognostic unfavourable (8.72e-5)" "unprognostic (8.48e-2)" "unprognostic (9.33e-2)" "prognostic favourable (1.22e-4)" "unprognostic (3.80e-3)" "unprognostic (8.71e-2)" "prognostic unfavourable (6.29e-6)" "unprognostic (3.40e-3)" "unprognostic (4.35e-2)" "unprognostic (5.35e-2)" "unprognostic (8.60e-2)" 6.5 5.5 6.4 11.4 10.6 21.9 6.6 11.0 7.5 6.8 6.6 9.2 1.6 8.6 6.8 4.4 14.1 6.0 5.7 5.1 6.7 4.8 8.7 5.9 5.5 9.2 10.6 5.8 7.3 7.0 6.2 4.1 11.8 6.1 5.3 5.7 5.5 8.8 4.3 7.1 13.4 7.1 4.4 7.8 12.0 7.4 14.1 8.4 44.8 8.6 13.4 17.4 6.0 8.0 11.3 7.8 7.1 6.8 12.9 8.6 5.0 14.8 11.2 6.8 6.8 1.0 1.9 8.4 6.9 2.9 10.4 12.1 8.8 5.7 15.9 10.5 1.6 8.9 5.5 6.8 5.7 8.6 15.0 7.6 11.9 6.8 0.7 7.0 7.1 1.0 1.7 8.8 3.2 4.0 10.5 4.7 4.9 25.5 12.8 6.9 6.7 19.6 13.8 9.8 11.4 2.6 5.9 14.1 8.2 7.5 2.7 3.1 7.4 4.3 3.8 12.4 6.2 17.6 11.4 11.5 12.7 12.6 7.3 11.2 10.0 7.1 6.8 6.4 8.6 6.6 7.0 9.8 7.0 6.1 4.2 11.3 6.6 6.5 6.8 12.9 5.9 7.8 5.5 5.0 6.4 10.6 11.0 7.5 6.7 4.8 10.6 5.8 6.1 8.4 RNASEL "PRCA1, RNS4" ENSG00000135828 "Ribonuclease L" Q05823 1 182573634-182589256 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002633, CAB010906" Approved Supported Cytosol Cytosol "CAB010906: AB_477444, HPA002633: AB_1856314" "unprognostic (3.46e-2)" "unprognostic (9.10e-2)" "unprognostic (7.74e-2)" "unprognostic (1.13e-1)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (6.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" "unprognostic (5.43e-2)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.81e-1)" 8.1 10.8 7.4 9.5 10.9 3.7 8.3 5.7 7.7 12.5 9.3 6.7 8.5 8.0 12.4 11.9 10.0 8.8 8.0 5.8 7.0 5.3 9.9 3.9 8.4 10.1 7.7 3.3 14.0 5.3 13.5 18.0 8.5 10.1 10.5 10.8 13.3 10.5 10.3 4.1 6.3 12.2 9.6 7.4 10.5 8.8 3.5 6.7 13.3 13.3 2.8 11.0 13.9 11.0 5.0 7.2 26.9 13.5 5.0 9.2 4.9 2.3 3.3 1.4 0.5 7.6 13.3 2.6 4.5 5.6 4.6 4.3 1.9 5.1 5.1 7.9 5.1 4.3 3.3 4.6 1.8 4.0 2.8 5.9 1.2 0.2 3.9 11.0 11.7 9.4 10.6 2.4 0.7 2.0 2.1 3.9 4.0 3.3 3.2 4.6 1.1 0.9 4.8 1.1 2.6 4.9 3.1 0.7 0.2 4.0 4.9 3.8 5.0 12.3 2.5 2.4 1.9 2.5 2.4 3.5 1.2 0.6 3.8 6.8 3.5 16.8 7.2 24.6 4.9 7.6 6.4 5.0 5.8 5.2 6.0 3.8 9.2 6.7 26.9 5.0 13.5 7.2 4.6 4.9 7.4 10.9 5.7 7.7 7.0 5.3 7.7 3.3 10.1 6.7 RNF103 "hkf-1, KF1, ZFP103" ENSG00000239305 "Ring finger protein 103" O00237 2 86603393-86623866 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 9.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057922 Approved "HPA057922: " "unprognostic (4.41e-1)" "unprognostic (1.56e-1)" "unprognostic (6.04e-2)" "unprognostic (3.26e-1)" "unprognostic (3.20e-2)" "unprognostic (1.79e-1)" "unprognostic (7.42e-2)" "unprognostic (8.37e-2)" "unprognostic (4.06e-1)" "unprognostic (1.13e-2)" "unprognostic (6.21e-2)" "unprognostic (1.44e-1)" "unprognostic (3.54e-3)" "unprognostic (1.50e-1)" "unprognostic (1.77e-1)" "unprognostic (3.67e-2)" "prognostic favourable (6.77e-5)" 13.2 13.5 18.0 9.8 20.6 9.8 18.5 38.3 24.6 15.8 28.1 16.9 9.6 15.6 18.8 39.7 11.7 12.7 23.3 29.5 16.7 15.9 13.1 43.8 8.6 8.5 17.8 10.6 13.2 20.2 23.8 12.2 16.2 14.7 20.5 14.2 14.5 13.8 16.1 17.7 10.4 27.2 17.9 21.8 8.1 18.7 13.7 16.5 11.9 9.0 8.8 8.3 13.4 11.5 1.4 1.6 9.9 0.9 3.0 3.4 0.9 5.6 7.7 3.9 6.0 18.0 11.7 6.4 8.1 12.5 4.2 5.7 4.4 9.7 9.4 9.9 12.2 6.9 5.2 6.4 6.4 7.8 7.1 5.3 3.5 9.8 17.1 1.7 8.0 16.9 13.5 6.2 7.8 12.6 1.9 5.7 11.5 6.9 4.0 4.7 1.8 5.5 2.5 16.9 5.5 15.4 8.9 6.2 6.4 9.6 21.5 8.0 8.2 4.4 14.2 8.2 3.9 8.2 4.8 19.9 6.6 6.3 6.5 3.0 3.9 6.5 0.7 9.9 1.1 0.9 1.5 1.4 1.6 2.4 1.6 1.4 1.9 1.3 1.5 3.0 0.6 1.0 3.4 0.9 18.0 20.6 38.3 24.6 16.7 15.9 17.8 10.6 14.7 16.5 RNF111 "ARK, Arkadia, DKFZP761D081, FLJ38008" ENSG00000157450 "Ring finger protein 111" Q6ZNA4 15 58865175-59097419 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038576, HPA038577" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA038576: AB_10964492, HPA038577: AB_10960052" "unprognostic (7.30e-2)" "unprognostic (2.60e-2)" "unprognostic (2.39e-1)" "unprognostic (3.37e-1)" "unprognostic (7.94e-2)" "unprognostic (2.09e-1)" "unprognostic (2.19e-1)" "unprognostic (3.21e-1)" "unprognostic (5.10e-2)" "unprognostic (6.12e-3)" "unprognostic (3.10e-2)" "unprognostic (1.42e-1)" "unprognostic (2.05e-3)" "unprognostic (2.05e-1)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (9.74e-2)" 12.8 11.2 15.3 15.6 19.3 21.2 12.7 24.1 21.9 15.1 9.8 18.8 10.9 11.4 16.4 9.8 16.2 12.6 13.0 11.0 13.0 13.0 12.9 14.8 13.3 13.9 15.7 15.5 16.8 14.8 20.8 19.2 16.7 17.8 12.7 10.3 12.9 14.9 12.5 15.0 14.1 10.9 11.7 14.2 14.3 12.0 15.7 16.9 14.9 16.4 6.5 17.8 15.8 14.8 7.9 5.2 26.7 9.9 3.3 6.1 2.0 9.7 22.7 14.5 12.4 12.6 14.2 12.4 12.8 15.0 12.8 16.5 9.9 6.5 12.0 14.5 17.8 19.2 3.9 9.5 16.0 12.4 8.1 14.9 9.2 7.6 13.7 8.6 16.8 11.1 10.4 13.8 15.3 14.2 13.7 12.1 15.7 4.7 11.4 5.6 11.9 8.8 11.5 20.7 9.8 9.8 17.5 11.9 17.4 11.5 11.4 11.1 8.9 10.7 16.3 20.5 17.2 10.7 12.2 8.7 11.9 14.3 12.5 14.0 15.4 6.4 9.9 9.3 4.8 7.0 4.8 7.4 4.9 4.3 5.2 7.9 5.5 4.2 26.7 3.3 7.6 4.9 6.1 2.0 15.3 19.3 24.1 21.9 13.0 13.0 15.7 15.5 17.8 16.9 RNF112 "BFP, ZNF179" ENSG00000128482 "Ring finger protein 112" Q9ULX5 17 19411125-19417276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 47.5" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.1;fHDF/TERT166: 4.7;SCLC-21H: 4.7;SH-SY5Y: 8.2;U-87 MG: 26.9" "Cancer enriched" "Detected in some" 8 "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015970 Supported Approved "Nuclear speckles" "Nuclear speckles" "HPA015970: AB_1859103" "unprognostic (1.16e-1)" "unprognostic (3.74e-1)" "unprognostic (8.43e-5)" "unprognostic (3.65e-2)" "unprognostic (2.96e-2)" "unprognostic (6.02e-2)" "unprognostic (1.27e-1)" "unprognostic (2.88e-1)" "unprognostic (4.26e-1)" "unprognostic (5.02e-2)" "unprognostic (3.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.31e-9)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (4.24e-1)" 2.5 8.1 11.3 2.3 15.9 0.6 1.8 47.5 29.1 1.2 3.6 1.4 0.0 2.9 2.0 6.9 1.1 1.5 4.4 2.3 12.4 8.2 1.2 0.7 1.7 1.4 3.9 14.1 1.3 0.8 0.5 1.9 1.1 3.1 10.2 4.4 1.6 1.3 3.5 2.1 1.9 3.6 3.5 2.9 1.7 2.1 2.0 3.7 0.0 0.9 0.0 0.8 2.8 1.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 4.1 0.1 0.2 0.9 0.0 0.0 0.2 0.0 0.0 0.0 4.7 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 3.3 0.0 0.0 1.7 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.1 0.1 0.1 0.0 0.0 4.7 8.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 26.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 15.9 47.5 15.9 12.4 8.2 3.9 14.1 3.1 3.7 RNF114 "PSORS12, ZNF313" ENSG00000124226 "Ring finger protein 114" Q9Y508 20 49936336-49953892 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 108.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021184 Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA021184: AB_1859185" "unprognostic (8.38e-2)" "unprognostic (3.56e-2)" "unprognostic (5.62e-2)" "prognostic unfavourable (8.10e-6)" "unprognostic (1.56e-1)" "unprognostic (2.96e-1)" "prognostic unfavourable (3.11e-4)" "unprognostic (2.50e-2)" "unprognostic (1.03e-2)" "unprognostic (2.12e-1)" "unprognostic (3.99e-1)" "unprognostic (2.70e-2)" "unprognostic (2.54e-3)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "prognostic favourable (3.01e-4)" "unprognostic (1.36e-2)" 23.2 21.3 24.4 18.3 25.7 31.2 20.6 26.7 23.1 24.0 29.7 32.6 21.1 29.5 20.3 23.4 20.2 23.6 20.1 21.9 23.0 25.3 30.3 31.6 24.4 24.0 28.3 19.4 28.4 36.8 16.1 21.6 40.6 23.7 24.5 21.3 27.1 27.8 24.1 43.8 15.2 33.9 17.6 29.3 36.3 24.2 101.9 24.1 28.3 37.9 20.0 24.1 22.6 25.0 28.5 32.5 43.4 44.6 23.7 29.4 34.9 15.6 15.4 7.9 8.3 16.3 11.3 23.3 14.0 15.9 29.0 12.3 45.7 12.9 7.6 28.0 7.4 12.6 11.8 14.1 10.0 13.7 8.6 9.6 10.3 32.1 14.3 17.4 11.6 9.8 13.0 11.1 7.6 6.9 18.0 8.9 8.5 52.6 14.6 18.1 8.2 22.1 16.0 8.3 13.7 15.3 12.8 12.1 8.7 17.1 108.1 21.6 28.8 16.2 9.1 26.3 12.2 13.8 16.1 18.3 19.1 14.4 14.9 11.4 14.5 38.5 42.5 35.7 22.0 39.2 24.6 28.2 24.6 22.4 32.5 28.5 29.4 23.7 43.4 23.7 44.6 26.7 28.8 34.9 24.4 25.7 26.7 23.1 23.0 25.3 28.3 19.4 23.7 24.1 RNF115 "CL469780, ZNF364" ENSG00000265491 "Ring finger protein 115" Q9Y4L5 1 145738868-145824077 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019130 Approved Approved Nucleoli,Mitochondria "Nucleoli, Mitochondria" "HPA019130: AB_1859220" "unprognostic (3.44e-2)" "unprognostic (2.47e-3)" "unprognostic (2.24e-1)" "unprognostic (1.09e-1)" "unprognostic (5.48e-2)" "unprognostic (1.90e-1)" "prognostic unfavourable (2.95e-4)" "unprognostic (2.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.35e-1)" "unprognostic (2.64e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-2)" "unprognostic (3.23e-1)" "unprognostic (4.77e-2)" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" 7.2 5.2 6.8 4.8 6.8 6.4 7.7 16.2 7.0 6.3 3.4 4.6 5.7 3.5 8.9 5.0 5.8 4.3 4.8 23.5 5.8 5.6 5.1 3.9 5.6 4.7 6.2 4.7 4.5 5.8 5.9 3.5 5.2 6.5 3.8 7.3 3.6 5.6 27.6 3.8 3.1 10.9 4.5 4.2 3.8 3.4 4.5 6.0 5.0 5.4 4.5 4.1 6.3 2.7 2.4 9.0 2.2 3.2 3.2 1.4 11.1 4.6 5.7 4.2 10.4 13.7 4.6 8.4 15.7 6.2 7.6 5.0 4.1 7.8 9.6 12.0 7.8 6.3 5.8 6.8 7.8 4.1 6.2 5.9 4.6 6.6 9.7 14.5 7.9 5.1 6.3 7.6 8.0 6.1 12.8 11.3 8.4 7.1 6.2 7.2 9.8 6.8 5.7 6.5 12.2 3.8 5.7 7.9 6.8 8.5 6.2 9.3 9.3 9.8 9.1 7.1 5.4 8.9 10.8 10.2 8.3 4.6 6.6 5.7 9.0 2.2 3.2 3.2 1.5 2.7 2.7 2.2 3.2 1.8 2.4 2.3 3.1 1.7 3.2 1.6 2.4 2.0 1.4 RNF123 "FLJ12565, KPC1" ENSG00000164068 "Ring finger protein 123" Q5XPI4 3 49689499-49721529 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065983, HPA071879" Approved Approved Cytosol Cytosol "HPA065983: , HPA071879: " "unprognostic (2.68e-1)" "unprognostic (3.34e-1)" "unprognostic (2.67e-1)" "unprognostic (1.04e-1)" "unprognostic (2.21e-1)" "unprognostic (9.51e-2)" "unprognostic (2.04e-1)" "unprognostic (3.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (5.03e-3)" "prognostic favourable (1.33e-8)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (7.22e-2)" "unprognostic (3.83e-1)" 5.3 8.0 7.7 8.0 10.4 17.5 5.0 13.8 13.6 5.2 6.8 6.2 7.8 12.7 6.4 8.0 7.5 6.4 7.0 12.9 8.5 6.8 8.4 21.8 5.7 6.1 7.3 6.6 5.1 7.7 8.9 8.4 7.3 6.6 7.3 4.8 7.6 6.9 6.7 81.2 7.7 12.5 6.2 6.7 7.6 6.9 8.8 7.8 8.3 6.2 12.0 9.1 6.6 4.8 11.3 12.7 11.8 10.9 7.7 11.4 5.3 6.7 9.5 11.4 11.7 17.3 10.7 12.3 8.8 11.7 11.2 12.5 10.1 11.7 16.4 8.0 12.5 8.5 8.6 13.3 7.9 10.9 11.7 13.4 18.8 22.2 17.3 12.9 14.5 13.5 13.1 10.5 12.3 11.6 14.0 14.3 9.5 10.1 13.6 21.0 6.2 15.4 6.4 6.9 17.0 15.4 11.4 7.8 15.6 12.1 10.8 13.4 11.1 23.3 11.9 9.9 12.1 8.9 10.8 19.4 19.0 6.6 14.0 16.4 14.8 11.8 10.9 7.9 11.4 9.5 6.8 9.8 7.2 6.8 8.6 11.3 8.7 8.2 6.3 7.7 9.7 12.7 5.5 5.3 7.7 10.4 13.8 13.6 8.5 6.8 7.3 6.6 6.6 7.8 RNF125 FLJ20456 ENSG00000101695 "Ring finger protein 125" Q96EQ8 18 32018372-32073213 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "HMC-1: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041514 Uncertain Supported "Nucleoli,Golgi apparatus" "Golgi apparatus" Nucleoli "HPA041514: AB_10795596" "unprognostic (2.13e-2)" "unprognostic (2.05e-2)" "unprognostic (2.88e-1)" "unprognostic (3.93e-1)" "unprognostic (5.03e-1)" "unprognostic (4.50e-2)" "unprognostic (2.30e-3)" "unprognostic (6.15e-2)" "unprognostic (4.21e-2)" "unprognostic (3.24e-1)" "unprognostic (1.68e-1)" "unprognostic (4.35e-2)" "prognostic unfavourable (4.06e-4)" "unprognostic (2.99e-1)" "unprognostic (4.12e-1)" "unprognostic (1.82e-1)" "unprognostic (7.07e-3)" 21.9 2.3 4.1 9.1 5.7 18.2 20.4 1.2 6.6 5.0 8.9 12.2 3.3 12.3 7.2 5.5 3.9 4.3 6.0 5.4 6.1 4.1 2.1 14.1 10.3 13.5 7.7 3.1 2.4 4.2 2.5 1.3 4.4 7.0 3.1 7.8 1.6 5.0 1.9 4.4 6.0 26.0 4.1 12.0 7.4 4.2 3.3 8.3 14.8 3.2 2.9 7.2 4.5 6.2 2.1 3.4 9.0 3.8 11.7 12.5 5.1 0.7 0.1 0.1 0.2 0.3 0.5 0.6 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 0.0 0.5 0.9 0.7 0.1 3.9 1.6 0.2 0.2 0.2 0.1 5.1 31.8 1.0 1.5 0.0 1.7 0.3 0.1 1.1 0.0 1.1 1.3 4.8 2.6 0.9 5.4 0.3 0.1 0.3 0.3 0.5 0.2 0.1 0.1 7.8 0.8 2.5 0.1 0.1 0.5 0.1 0.0 3.7 0.1 0.1 0.4 6.8 4.2 9.0 3.8 3.3 12.5 2.0 8.2 2.0 10.1 10.5 3.4 2.1 8.2 10.6 1.5 11.7 1.9 3.4 10.0 5.1 4.1 5.7 1.2 6.6 6.1 4.1 7.7 3.1 7.0 8.3 RNF126 FLJ20552 ENSG00000070423 "Ring finger protein 126" Q9BV68 19 647526-663277 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043050 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA043050: AB_10794768" "unprognostic (2.24e-1)" "unprognostic (1.64e-1)" "unprognostic (1.97e-1)" "unprognostic (2.48e-3)" "unprognostic (1.90e-1)" "unprognostic (2.32e-1)" "unprognostic (1.09e-3)" "unprognostic (3.57e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (9.96e-3)" "unprognostic (7.04e-3)" "unprognostic (3.39e-2)" "unprognostic (2.05e-1)" "unprognostic (4.67e-2)" 14.2 14.2 13.4 17.0 13.7 18.7 14.5 12.2 24.7 9.8 16.0 14.8 7.4 24.3 10.4 9.2 19.8 9.5 13.1 14.2 13.1 10.2 11.6 27.9 10.4 19.9 11.4 11.6 12.1 22.4 5.9 10.0 14.1 12.3 10.0 6.3 10.1 13.2 9.3 50.3 21.9 20.3 9.9 10.0 18.6 21.0 33.6 9.3 16.1 8.6 19.5 18.6 13.1 11.2 15.9 13.6 7.5 13.8 17.1 17.3 9.2 25.9 8.6 7.3 10.4 1.7 2.4 12.5 13.7 5.2 7.9 7.5 17.4 9.1 21.5 8.9 5.7 17.5 4.4 10.2 2.2 14.2 31.8 10.9 9.0 14.4 6.6 21.7 16.1 4.1 8.1 6.5 5.1 7.2 21.9 21.7 4.1 20.9 22.1 10.2 19.5 17.0 16.1 6.3 33.9 6.0 14.5 17.5 13.6 10.3 13.6 14.0 8.7 17.1 9.4 14.4 10.4 21.1 23.3 38.4 19.0 25.2 18.3 12.7 14.8 0.6 9.8 7.5 17.3 11.5 14.2 15.9 15.7 16.7 12.4 15.6 12.2 11.4 2.2 17.1 13.8 13.6 16.8 9.2 13.4 13.7 12.2 24.7 13.1 10.2 11.4 11.6 12.3 9.3 RNF128 "FLJ23516, GRAIL" ENSG00000133135 "Ring finger protein 128, E3 ubiquitin protein ligase" Q8TEB7 X 106693794-106796993 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 54.6;liver: 48.4;thyroid gland: 38.4" "Cell line enhanced" "Detected in some" "BEWO: 17.9;CAPAN-2: 14.8;Hep G2: 12.6;RPTEC TERT1: 13.0;RT4: 37.2;WM-115: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019675 Uncertain "HPA019675: " "unprognostic (1.78e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-3)" "unprognostic (1.92e-4)" "unprognostic (2.14e-3)" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (1.55e-2)" "unprognostic (1.75e-2)" "prognostic unfavourable (1.07e-7)" "unprognostic (1.11e-2)" "unprognostic (7.61e-2)" "unprognostic (6.30e-2)" "unprognostic (5.30e-3)" 1.4 20.6 2.4 2.2 7.2 0.0 3.0 0.7 4.2 0.5 24.4 0.9 0.4 24.2 0.2 2.2 4.0 0.3 27.2 0.6 2.8 5.1 24.4 48.4 6.7 0.0 2.4 2.1 0.7 14.5 0.0 11.0 10.5 4.0 3.4 7.8 0.0 25.4 0.8 3.0 3.6 54.6 0.9 1.1 0.2 17.9 0.3 1.0 1.1 38.4 2.3 2.7 10.2 3.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 4.5 0.0 0.0 0.0 1.5 0.8 17.9 0.0 0.1 0.0 0.0 7.8 14.8 0.0 0.0 0.2 5.6 0.0 0.0 0.0 0.0 8.7 0.0 0.1 12.6 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 13.0 37.2 0.0 0.0 0.0 0.9 0.9 0.9 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 7.2 0.7 4.2 2.8 5.1 2.4 2.1 4.0 1.0 RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812708-149962139 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 72.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Vesicles" Cytosol "HPA064784: " "unprognostic (1.27e-1)" "unprognostic (2.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (8.49e-2)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (6.94e-3)" "unprognostic (1.13e-1)" "prognostic favourable (2.00e-8)" "unprognostic (2.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.79e-1)" 24.0 21.3 30.6 19.0 39.4 9.8 28.5 19.9 30.4 19.0 17.7 39.9 16.2 14.3 16.8 33.7 16.8 15.9 20.4 16.4 40.5 29.7 35.8 39.2 31.7 19.6 60.9 26.8 18.1 19.6 23.5 14.9 32.4 40.7 25.5 20.3 19.5 36.1 20.9 18.0 18.4 16.3 20.4 102.2 25.5 17.0 12.5 51.2 13.3 32.1 18.8 15.9 21.4 16.5 8.8 15.7 72.4 31.5 7.8 8.5 14.6 19.4 12.1 8.2 9.3 32.3 19.8 13.7 10.8 27.8 10.4 15.5 10.6 28.0 8.1 15.8 13.2 18.5 11.0 13.8 14.7 9.9 8.0 9.7 5.6 10.3 21.5 10.4 13.9 20.9 26.3 8.8 23.9 11.5 3.0 16.5 9.3 10.9 7.5 6.9 5.5 9.5 5.4 8.8 34.3 20.2 9.1 4.3 12.5 8.9 13.4 34.7 25.5 11.1 12.0 14.2 5.7 15.0 6.9 28.0 18.4 16.7 11.9 9.8 7.6 12.9 20.3 16.6 6.8 25.2 8.5 8.8 7.6 7.6 15.7 8.3 7.3 7.5 72.4 7.8 31.5 11.2 8.3 14.6 30.6 39.4 19.9 29.2 40.5 29.7 60.9 26.8 40.7 51.2 RNF130 "G1RZFP, GOLIATH, GP" ENSG00000113269 "Ring finger protein 130" Q86XS8 5 179911651-180072118 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 17.0;classical monocyte: 38.1;eosinophil: 24.6;intermediate monocyte: 27.5;myeloid DC: 31.1;neutrophil: 68.1;non-classical monocyte: 23.8;plasmacytoid DC: 22.9" "Group enriched" "Detected in all" 11 "dendritic cells: 31.1;granulocytes: 68.1;monocytes: 38.1" "Low region specificity" "Detected in all" HPA014499 Approved "HPA014499: AB_1856328" "unprognostic (2.01e-1)" "prognostic favourable (6.32e-4)" "unprognostic (2.43e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-3)" "unprognostic (2.93e-2)" "unprognostic (1.78e-1)" "unprognostic (4.00e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (8.41e-2)" "unprognostic (4.17e-2)" "unprognostic (4.32e-1)" "unprognostic (1.38e-2)" 36.3 16.3 23.5 16.3 32.5 29.5 24.0 19.0 25.3 26.0 16.7 56.0 19.0 10.6 18.5 12.0 10.6 19.5 21.9 17.0 27.8 21.1 20.7 64.4 25.5 19.1 50.2 20.3 21.7 28.6 11.0 16.7 19.8 30.3 16.3 16.1 15.8 30.6 28.3 17.3 7.9 12.1 22.2 58.2 20.4 20.5 7.3 38.8 2.5 14.3 6.3 10.3 20.7 13.3 1.2 31.1 68.1 38.1 4.0 2.0 20.3 7.9 5.8 28.6 20.9 27.9 15.2 5.4 6.2 7.8 6.8 7.4 1.8 6.8 0.0 19.2 10.8 0.8 19.9 12.6 7.5 0.1 17.7 15.6 3.2 4.0 7.1 3.8 41.0 14.3 6.7 0.5 3.9 11.1 3.2 0.1 6.8 12.0 7.1 12.1 7.8 8.9 16.0 6.6 0.0 8.6 1.4 17.4 7.8 11.6 6.3 24.0 9.1 9.0 8.6 11.6 4.6 8.1 6.6 0.0 6.1 1.6 1.4 30.1 9.0 17.0 38.1 24.6 2.0 27.5 1.9 1.2 0.9 1.0 31.1 1.2 1.0 1.2 68.1 4.0 23.8 22.9 0.1 20.3 23.5 32.5 19.0 25.3 27.8 21.1 50.2 20.3 30.3 38.8 RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30968785-30999911 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles Vesicles "HPA021576: AB_1856331, HPA052404: " "unprognostic (1.13e-1)" "unprognostic (1.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-2)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "prognostic unfavourable (7.51e-5)" "unprognostic (6.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (4.47e-1)" 18.2 11.6 6.5 15.9 7.1 7.1 28.8 6.4 6.1 16.3 22.2 7.2 16.5 9.7 15.7 16.8 18.4 11.8 14.4 7.4 7.1 4.8 19.5 6.0 19.0 28.0 6.8 2.5 15.1 11.7 15.0 5.9 19.2 6.3 18.1 13.2 13.6 13.3 14.8 7.5 21.4 16.7 13.9 6.1 22.7 10.0 8.8 4.8 6.0 25.0 12.7 18.8 13.0 19.1 11.8 18.4 21.7 25.1 5.4 5.3 9.7 5.8 12.2 0.7 12.1 16.7 13.3 10.3 4.7 7.0 4.6 4.0 0.0 4.4 4.7 6.9 8.9 7.5 6.0 5.7 3.6 4.5 2.6 2.2 3.6 0.0 11.7 5.9 5.1 13.2 30.2 4.8 15.6 7.2 0.0 16.2 7.3 7.8 0.0 6.0 4.9 6.6 12.4 0.0 17.3 6.3 8.4 4.5 0.2 6.7 2.8 6.7 18.5 9.2 6.3 0.0 1.6 7.4 5.3 0.2 0.5 3.4 8.1 10.2 6.2 9.1 24.0 12.1 5.3 21.8 2.9 11.8 2.8 2.7 18.4 11.2 1.5 2.7 21.7 5.4 25.1 6.6 3.8 9.7 6.5 7.1 6.4 6.1 7.1 4.8 6.8 2.5 6.3 4.8 RNF138 "NARF, STRIN" ENSG00000134758 "Ring finger protein 138" Q8WVD3 18 32091855-32131561 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 43.8;bone marrow: 40.4;lymphoid tissue: 28.3;testis: 73.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041101 Approved Mitochondria Mitochondria "HPA041101: AB_10805837" "unprognostic (2.37e-2)" "unprognostic (4.63e-3)" "unprognostic (2.03e-3)" "unprognostic (1.01e-1)" "unprognostic (2.34e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (6.90e-2)" "unprognostic (1.27e-2)" "unprognostic (6.15e-2)" "unprognostic (9.52e-3)" "unprognostic (2.77e-1)" "unprognostic (9.58e-2)" "unprognostic (1.90e-1)" 8.2 5.0 6.5 11.0 7.4 40.4 7.7 9.9 7.1 6.5 11.0 9.0 5.8 8.0 7.5 6.3 7.4 9.7 7.1 5.0 6.8 6.4 5.9 10.1 7.6 17.9 10.6 6.3 9.0 7.8 5.6 8.7 7.2 6.7 6.5 10.0 4.5 6.9 4.9 5.1 5.6 11.2 5.6 9.1 14.3 6.6 73.4 8.1 28.3 7.0 5.7 9.9 6.1 6.8 14.4 24.3 25.7 24.9 16.4 43.8 24.2 8.9 5.3 22.0 10.9 2.8 6.0 12.5 9.2 5.2 11.5 13.4 6.2 6.3 21.6 11.5 6.0 9.4 11.5 10.4 15.7 12.0 19.2 17.0 6.9 7.6 11.3 46.8 15.1 5.8 10.4 12.7 18.1 11.7 23.4 8.9 7.4 8.5 31.6 21.0 24.6 7.4 32.7 13.8 12.4 10.5 6.7 25.0 12.5 12.3 7.1 9.5 4.6 19.8 9.0 13.9 10.2 3.4 10.2 14.8 19.5 37.5 7.6 26.2 13.6 8.0 24.9 24.0 10.5 18.6 13.4 14.0 22.9 14.8 24.3 14.4 43.8 27.9 25.7 16.4 15.3 10.5 16.7 24.2 6.5 7.4 9.9 7.1 6.8 6.4 10.6 6.3 6.7 8.1 RNF139 "HRCA1, RCA1, TRC8" ENSG00000170881 "Ring finger protein 139" Q8WU17 8 124474738-124487914 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001202 Approved "HPA001202: AB_1079824" "unprognostic (3.28e-3)" "unprognostic (2.92e-2)" "unprognostic (5.16e-2)" "unprognostic (5.43e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (2.71e-2)" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-1)" "prognostic unfavourable (3.54e-4)" "unprognostic (9.85e-2)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" "unprognostic (7.75e-2)" "unprognostic (1.45e-1)" 15.1 17.3 10.4 9.5 12.2 54.5 13.4 12.0 17.1 14.2 10.9 14.0 9.4 6.2 15.3 10.0 12.2 14.2 11.0 11.4 10.4 10.8 11.4 17.7 11.3 14.2 12.4 11.5 17.1 10.3 7.6 10.6 18.4 9.9 12.8 10.4 10.2 10.3 10.5 15.2 12.6 11.3 14.2 12.2 11.8 11.2 60.3 13.3 16.8 11.2 9.6 10.4 14.8 10.7 9.2 9.4 11.8 11.7 8.6 13.9 8.0 13.2 8.9 10.7 10.5 23.6 18.8 8.8 11.9 22.6 10.0 12.9 5.7 11.1 13.7 14.0 15.4 9.8 9.1 14.5 15.0 18.9 11.4 20.3 5.8 11.7 18.0 9.6 11.8 16.0 21.2 10.6 28.7 13.3 14.3 21.0 11.8 35.8 16.2 6.9 7.5 12.6 6.5 7.9 13.7 18.8 17.0 4.5 11.7 15.5 38.9 16.8 18.7 10.4 10.5 6.7 15.5 11.3 13.2 17.1 18.1 12.4 10.5 16.3 6.7 3.3 7.4 11.8 11.6 4.7 13.9 9.2 10.8 13.2 9.4 8.5 10.8 11.3 10.8 8.6 11.7 5.1 13.2 8.0 10.4 12.2 12.0 17.1 10.4 10.8 12.4 11.5 9.9 13.3 RNF14 "ARA54, HFB30, TRIAD2" ENSG00000013561 "Ring finger protein 14" Q9UBS8 5 141958328-141990291 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008716 Approved Supported Cytosol Cytosol "HPA008716: AB_1856337" "unprognostic (7.45e-3)" "unprognostic (1.38e-1)" "unprognostic (8.56e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-2)" "unprognostic (7.24e-3)" "unprognostic (2.35e-1)" "unprognostic (4.05e-2)" "unprognostic (5.22e-2)" "unprognostic (7.42e-2)" "unprognostic (7.92e-2)" "unprognostic (1.46e-1)" "prognostic favourable (1.71e-4)" "unprognostic (6.89e-3)" "unprognostic (2.82e-1)" "prognostic unfavourable (2.21e-4)" "unprognostic (1.06e-2)" 21.2 29.5 23.7 11.2 33.9 7.8 22.0 22.5 40.2 18.4 18.7 26.2 16.0 15.3 21.0 21.5 15.6 14.3 15.4 32.9 23.6 24.7 31.3 31.3 13.8 13.3 28.9 17.3 15.9 17.1 26.3 28.8 23.6 47.7 21.6 19.8 20.9 18.1 20.1 27.7 11.9 20.9 20.5 26.3 13.8 15.7 33.7 15.0 16.2 26.3 13.3 14.9 16.7 14.0 12.3 17.1 32.6 18.8 16.8 17.0 12.2 12.5 21.0 14.8 29.0 26.6 27.9 9.9 25.8 14.4 18.2 20.2 17.4 14.7 22.2 30.3 26.5 6.9 18.8 25.4 16.3 16.7 16.2 14.1 11.0 7.9 29.3 15.5 12.6 20.9 22.4 24.1 30.4 22.5 17.1 31.1 37.2 15.0 15.0 4.9 6.2 24.0 9.9 16.4 24.1 25.0 21.8 16.3 13.3 22.6 41.5 43.9 28.9 12.1 23.2 24.2 7.8 11.4 24.4 19.6 22.8 20.4 20.7 19.0 29.8 32.6 13.4 13.0 17.0 15.8 16.5 12.3 15.0 16.9 16.2 10.6 11.5 16.7 3.3 16.8 18.8 17.1 16.7 12.2 23.7 33.9 22.5 40.2 23.6 24.7 28.9 17.3 47.7 15.0 RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917392-7068286 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.5" "Cell line enhanced" "Detected in many" "HMC-1: 50.4;SH-SY5Y: 15.3;SK-MEL-30: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 8.7" "Group enriched" "Detected in many" 7 "granulocytes: 8.7;T-cells: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049939 Approved Approved Vesicles Vesicles "HPA049939: " "unprognostic (1.78e-1)" "unprognostic (2.53e-3)" "unprognostic (8.37e-2)" "prognostic unfavourable (6.00e-4)" "unprognostic (6.57e-2)" "prognostic favourable (6.96e-4)" "unprognostic (7.04e-6)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "unprognostic (5.64e-1)" "unprognostic (9.11e-2)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "prognostic unfavourable (7.32e-5)" "unprognostic (1.30e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-3)" 12.9 28.8 13.3 4.2 21.2 12.1 11.1 45.5 20.7 17.3 5.2 28.7 9.0 3.0 26.0 8.3 4.7 8.4 7.5 8.0 15.6 11.6 7.5 1.8 5.7 7.9 26.5 12.2 20.0 29.7 21.5 12.5 6.2 13.2 8.7 5.7 5.9 4.0 7.4 8.7 5.7 4.1 12.2 21.8 21.1 2.8 5.0 27.1 3.4 3.2 1.2 5.8 5.8 6.5 0.1 0.2 8.7 0.1 0.8 4.1 0.6 0.3 2.2 11.7 2.4 2.6 5.5 9.0 0.0 0.0 0.4 1.1 0.0 0.2 1.1 1.3 0.1 0.2 3.8 0.0 0.0 0.6 1.0 14.9 0.1 4.4 0.1 0.2 50.4 8.7 0.0 0.8 0.0 0.0 6.4 0.2 0.0 1.8 7.6 0.6 4.3 5.3 5.9 8.5 0.9 0.3 3.9 3.9 15.3 0.2 1.5 15.1 0.6 0.9 0.0 1.5 4.0 4.1 1.7 4.1 1.3 0.0 5.8 3.3 5.5 1.5 0.1 8.7 2.1 0.0 3.0 0.1 2.1 1.5 0.2 0.1 4.1 2.8 0.4 0.8 0.0 0.0 0.8 0.6 13.3 21.2 45.5 20.3 15.6 11.6 26.5 12.2 13.2 27.1 RNF144B "bA528A10.3, IBRDC2, P53RFP" ENSG00000137393 "Ring finger protein 144B" Q7Z419 6 18387350-18468874 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 54.7;hTCEpi: 17.4;HUVEC TERT2: 16.1;TIME: 16.1;U-698: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 28.8" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;granulocytes: 15.6;monocytes: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046013, HPA054127, HPA072469" Uncertain Approved Nucleoli,Mitochondria Nucleoli Mitochondria "CAB046013: AB_11126028, HPA054127: , HPA072469: " "unprognostic (2.24e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (4.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.48e-3)" "unprognostic (5.89e-2)" "unprognostic (1.18e-2)" "unprognostic (6.55e-2)" "unprognostic (2.87e-3)" "unprognostic (2.44e-2)" "unprognostic (2.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" 16.3 2.0 4.6 11.1 6.8 15.7 21.1 5.1 7.5 8.0 4.2 2.8 4.6 1.5 6.8 7.5 9.4 9.0 6.8 8.7 5.3 4.3 13.8 11.4 39.0 11.1 8.3 2.3 4.2 3.7 3.0 2.3 11.1 8.8 12.8 2.3 8.3 16.9 6.2 36.8 19.2 3.7 4.9 9.2 37.1 4.3 3.3 6.9 5.8 32.9 11.4 12.2 7.3 6.6 2.0 7.9 15.6 28.8 0.2 0.7 2.6 1.3 0.2 0.1 0.0 0.0 0.6 2.9 1.5 1.6 3.2 3.5 0.0 0.1 54.7 15.0 0.6 4.7 0.0 4.6 4.6 0.2 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.8 17.4 1.2 3.9 16.1 0.0 0.0 0.8 0.5 0.4 0.0 0.4 0.3 0.2 0.5 3.3 9.8 3.0 0.5 0.0 0.3 7.0 5.2 8.2 0.1 16.1 2.5 0.5 0.2 0.3 0.0 0.0 46.0 0.3 0.1 0.2 0.1 9.1 5.1 0.2 16.4 0.7 2.0 0.3 0.3 5.6 1.6 0.7 0.4 15.6 0.2 28.8 7.9 0.2 2.6 4.6 6.8 5.1 7.5 5.3 4.3 8.3 2.3 8.8 6.9 RNF145 FLJ31951 ENSG00000145860 "Ring finger protein 145" Q96MT1 5 159157409-159210053 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036562 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "HPA036562: AB_10696657" "unprognostic (1.57e-1)" "unprognostic (9.02e-3)" "unprognostic (4.11e-2)" "unprognostic (3.88e-2)" "unprognostic (3.24e-2)" "unprognostic (2.93e-2)" "prognostic unfavourable (1.64e-6)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.54e-1)" "unprognostic (3.53e-1)" "unprognostic (1.67e-1)" "unprognostic (8.92e-3)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" 13.3 20.1 23.9 15.6 23.0 7.1 24.1 30.2 27.3 11.3 11.7 5.7 5.3 4.7 12.6 13.6 26.7 11.4 20.8 16.8 22.0 8.4 8.2 6.1 30.7 36.3 17.5 9.7 14.1 6.0 26.9 29.0 21.9 18.5 11.8 12.6 10.2 17.8 14.8 5.5 14.9 11.0 13.8 12.4 12.7 11.2 7.9 18.0 12.4 14.3 8.0 19.6 19.3 15.7 8.9 2.7 14.4 2.6 2.1 6.2 1.3 20.1 20.0 30.7 36.8 32.5 14.5 6.0 16.2 28.3 15.0 24.4 6.9 16.8 6.9 29.1 14.2 26.5 24.2 21.3 26.5 28.5 8.6 14.6 22.7 5.7 13.9 9.6 14.0 8.9 38.5 13.9 20.5 14.7 14.5 26.8 14.0 0.5 10.9 3.0 13.2 10.2 14.6 13.4 13.8 20.0 7.0 11.2 20.7 16.3 17.5 26.6 12.3 8.8 15.6 16.8 15.5 13.4 28.6 5.9 8.3 6.5 19.6 12.0 36.0 2.8 2.6 14.4 3.2 2.5 3.7 8.9 4.7 3.8 1.9 4.4 6.2 4.3 9.7 2.1 2.2 2.7 5.7 1.3 23.9 23.0 30.2 27.3 22.0 8.4 17.5 9.7 18.5 18.0 RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266610-127288567 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: AB_10600772, HPA027209: AB_10602312" "unprognostic (8.22e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (1.37e-1)" "unprognostic (5.47e-3)" "unprognostic (1.87e-1)" "unprognostic (6.74e-2)" "prognostic favourable (5.26e-5)" "unprognostic (2.65e-2)" "prognostic favourable (7.32e-4)" "unprognostic (4.04e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "unprognostic (2.15e-2)" 27.3 20.9 28.5 16.6 29.1 5.1 23.9 63.7 34.5 22.7 18.6 29.2 10.5 11.8 32.0 35.2 14.2 17.9 21.3 25.2 26.3 21.7 20.9 16.8 21.0 17.3 30.0 27.7 28.5 12.6 26.5 27.4 27.8 31.3 18.6 17.6 17.5 16.7 20.3 55.9 16.0 15.2 26.1 28.7 24.6 15.5 16.3 27.7 9.2 26.7 15.5 17.6 19.2 18.7 11.7 14.2 22.8 22.8 11.5 10.3 9.1 5.5 7.0 26.7 23.5 24.7 24.8 9.7 18.9 30.2 10.1 14.5 9.1 8.4 10.0 13.4 15.4 7.1 7.9 8.8 14.8 11.5 6.9 12.7 8.4 12.7 24.5 7.5 9.0 21.6 18.7 11.4 22.8 17.7 13.6 9.8 22.2 10.6 7.3 13.6 9.7 7.3 9.4 6.9 5.0 14.4 6.1 16.0 16.1 7.3 10.4 11.6 7.1 26.0 20.8 17.8 5.9 18.4 13.3 14.2 8.8 6.6 13.6 13.2 16.8 16.8 18.9 16.1 9.3 20.0 9.7 11.1 8.0 10.3 14.2 11.7 7.3 10.2 22.8 11.5 22.8 7.1 8.6 9.1 28.5 29.1 63.7 34.5 26.3 21.7 30.0 27.7 31.3 27.7 RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 123.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "neutrophil: 123.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 123.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "HPA011424: AB_1079825" "unprognostic (2.56e-2)" "unprognostic (4.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (3.17e-2)" "unprognostic (5.17e-3)" "unprognostic (4.16e-2)" "unprognostic (4.77e-3)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (5.69e-3)" "unprognostic (1.51e-1)" "prognostic unfavourable (2.04e-8)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.70e-1)" "prognostic favourable (2.91e-4)" 20.3 13.4 7.9 29.0 10.9 32.9 13.5 7.9 10.8 12.5 16.6 10.8 11.4 12.3 11.3 12.8 28.9 14.3 14.5 12.1 9.5 9.4 15.1 19.6 24.5 47.4 13.7 6.2 14.3 21.1 14.3 10.6 19.4 11.2 11.1 12.0 12.8 15.8 8.1 8.8 20.2 16.8 9.6 13.9 65.0 13.8 15.2 9.7 17.0 12.7 13.1 24.4 14.9 17.2 2.1 9.3 123.7 21.3 2.3 9.0 9.9 9.6 5.7 4.3 5.5 16.3 16.4 25.5 12.0 15.8 16.2 18.3 14.4 25.6 2.8 14.5 11.8 19.7 6.1 12.2 15.1 8.4 8.4 6.0 5.1 24.3 21.8 6.4 9.7 15.0 20.1 19.2 12.7 29.5 5.2 9.0 16.2 8.2 8.6 6.5 3.0 10.4 5.6 7.2 11.1 19.1 23.7 5.7 4.2 7.2 17.9 17.3 4.8 8.7 19.5 8.2 4.7 12.2 2.6 18.3 10.7 0.1 2.6 9.0 6.0 5.8 13.0 14.8 8.2 20.4 7.4 2.1 7.3 8.1 4.8 1.5 5.1 5.3 123.7 2.3 21.3 9.3 9.0 9.9 7.9 10.9 7.9 10.8 9.5 9.4 13.7 6.2 11.2 9.7 RNF157 KIAA1917 ENSG00000141576 "Ring finger protein 157" Q96PX1 17 76142453-76240373 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;skeletal muscle: 52.2;testis: 24.7" "Cell line enhanced" "Detected in many" "HDLM-2: 41.3;U-266/70: 21.9;U-266/84: 17.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.5;T-cells: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021854, HPA021991, HPA023922" Uncertain Approved "Golgi apparatus,Vesicles" "Golgi apparatus" Vesicles "HPA021854: AB_10600307, HPA021991: AB_10601112, HPA023922: AB_10602202" "unprognostic (4.21e-1)" "unprognostic (4.62e-2)" "unprognostic (1.55e-2)" "unprognostic (2.63e-3)" "unprognostic (4.93e-2)" "unprognostic (5.06e-2)" "unprognostic (2.07e-3)" "unprognostic (4.21e-1)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (1.04e-3)" "unprognostic (4.02e-1)" "unprognostic (8.26e-2)" "unprognostic (8.69e-3)" "unprognostic (2.28e-1)" "unprognostic (2.75e-2)" "unprognostic (1.38e-1)" 10.5 3.5 21.0 3.4 19.4 2.3 2.5 10.7 36.5 1.5 7.6 8.0 0.4 8.2 1.9 3.6 1.5 2.4 1.8 3.6 26.4 15.5 5.1 1.4 1.4 4.5 19.7 12.0 1.4 3.6 8.8 2.7 2.1 25.3 1.8 6.6 6.8 1.9 2.0 52.2 1.5 7.3 2.2 11.3 3.0 2.4 24.7 5.9 0.0 3.8 1.5 2.8 1.5 0.5 0.7 0.4 2.5 0.3 1.1 8.5 1.4 0.1 3.4 12.4 4.5 4.0 2.0 5.7 0.1 3.9 0.8 0.4 1.4 1.3 0.0 1.8 0.3 0.1 10.9 0.0 0.7 41.3 3.7 0.0 1.2 1.9 0.6 0.5 4.7 1.1 0.0 1.5 0.0 0.1 6.4 0.1 1.5 3.3 1.8 0.3 2.0 8.8 0.0 0.1 0.0 1.5 1.3 2.2 10.2 2.2 0.0 4.9 0.3 2.1 0.0 0.8 1.0 6.1 3.9 21.9 17.6 0.0 0.3 0.0 6.3 2.5 0.3 0.4 2.3 0.2 4.9 0.3 5.1 4.0 0.2 0.7 8.5 5.5 1.7 1.1 0.3 0.4 2.1 1.4 21.0 19.4 10.7 36.5 26.4 15.5 19.7 12.0 25.3 5.9 RNF165 "ARKL2, RNF111L2" ENSG00000141622 "Ring finger protein 165" Q6ZSG1 18 46326809-46463140 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.6" "Cell line enhanced" "Detected in some" "AF22: 12.5;HaCaT: 6.8;HeLa: 6.7;RPMI-8226: 6.5;SCLC-21H: 12.9;SH-SY5Y: 14.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "MAIT T-cell: 1.1;NK-cell: 3.9;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;NK-cells: 3.9;T-cells: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041615, HPA047798" Uncertain Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA041615: , HPA047798: " "unprognostic (6.46e-3)" "unprognostic (7.25e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-5)" "unprognostic (3.43e-1)" "unprognostic (4.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.04e-3)" "unprognostic (1.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.07e-1)" "unprognostic (1.87e-5)" "unprognostic (3.53e-3)" "unprognostic (1.90e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" 1.9 1.7 9.9 1.0 9.5 0.9 2.1 28.6 13.8 1.0 0.8 1.7 1.7 0.4 1.0 8.4 2.7 3.0 1.0 2.5 6.1 4.4 2.3 8.3 1.0 0.9 2.2 7.2 0.5 1.0 13.1 4.8 0.8 2.0 3.6 0.6 2.7 1.4 3.9 3.6 3.5 1.0 0.7 1.7 5.3 0.7 1.3 1.0 1.7 8.8 1.2 1.3 1.2 1.0 0.0 1.5 0.5 0.0 3.9 1.1 0.0 1.5 0.1 12.5 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 6.8 0.5 1.0 0.0 0.0 1.0 0.1 6.7 0.0 0.0 2.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.3 1.0 1.7 1.2 2.4 0.5 6.5 0.8 2.1 12.9 14.7 2.3 0.0 0.0 0.3 0.5 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 4.0 0.4 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.9 0.0 1.5 0.0 0.0 9.9 9.5 28.6 13.8 6.1 4.4 2.2 7.2 2.0 1.0 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved "HPA049810: " "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favourable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favourable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 30.5 45.9 45.8 32.1 47.0 40.7 38.3 37.9 67.9 44.3 43.5 54.6 49.2 42.7 43.1 55.8 51.6 44.0 47.4 40.1 43.1 39.9 44.1 84.1 35.6 38.7 43.7 43.6 42.6 52.4 52.8 40.7 49.0 41.2 43.6 46.7 38.5 49.1 51.7 56.5 51.6 51.1 42.4 46.4 47.1 42.7 42.0 33.1 53.9 55.1 47.3 47.6 48.1 40.7 25.6 18.2 54.4 26.7 27.6 53.0 37.9 23.7 34.5 15.0 18.4 37.0 18.5 22.4 14.7 20.5 31.1 24.6 24.0 10.9 17.6 28.6 24.2 36.5 26.1 28.5 23.2 16.9 41.9 30.0 43.5 23.6 28.0 14.1 63.2 21.7 45.1 32.3 30.8 20.0 11.7 60.0 24.8 17.0 22.3 17.6 17.9 22.2 15.3 14.9 21.8 35.8 19.9 11.8 14.7 13.5 23.2 19.5 22.2 14.4 12.2 18.6 12.3 16.6 27.9 19.9 20.2 5.8 25.6 20.3 19.4 22.4 21.4 54.4 53.0 22.6 41.1 25.6 40.6 52.7 18.2 24.0 28.5 42.3 52.1 27.6 26.7 18.0 37.7 37.9 45.8 47.0 37.9 67.9 43.1 39.9 43.7 43.6 41.2 33.1 RNF168 FLJ35794 ENSG00000163961 "Ring finger protein 168" Q8IYW5 3 196468783-196503768 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046109 Enhanced "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA046109: " "unprognostic (6.15e-3)" "prognostic favourable (8.21e-4)" "unprognostic (3.11e-1)" "unprognostic (1.11e-2)" "unprognostic (4.22e-1)" "unprognostic (5.04e-2)" "prognostic unfavourable (2.29e-4)" "unprognostic (6.81e-3)" "unprognostic (5.30e-2)" "unprognostic (1.63e-1)" "prognostic unfavourable (8.31e-4)" "unprognostic (4.83e-3)" "unprognostic (2.80e-3)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (1.95e-2)" "unprognostic (6.65e-2)" 20.8 9.3 8.9 10.7 11.1 31.6 18.7 21.1 13.0 13.6 11.2 10.7 12.3 11.1 13.9 8.5 14.3 10.1 10.9 12.0 10.2 10.2 7.5 18.8 14.3 12.0 13.8 11.0 14.6 9.2 12.0 8.1 9.9 15.3 10.1 10.8 9.1 11.0 13.6 20.8 20.1 10.1 12.9 10.5 11.7 10.7 18.4 13.4 17.6 9.6 13.9 15.2 14.7 17.1 6.2 5.8 21.8 10.0 7.7 11.6 5.7 12.3 4.9 8.9 11.6 8.3 6.1 12.7 7.6 4.8 5.1 8.1 9.6 6.1 13.1 17.6 6.3 12.6 12.4 9.0 7.9 6.2 6.1 24.9 12.5 11.9 4.3 7.6 6.2 6.0 3.5 8.0 7.1 7.4 7.4 13.8 5.1 20.9 25.1 4.5 10.5 6.5 11.3 10.3 10.6 4.3 17.1 7.4 7.5 8.6 10.6 6.5 16.0 6.8 7.3 8.9 7.0 9.4 10.0 11.8 11.1 19.9 8.7 9.2 7.0 21.8 6.6 7.5 11.6 7.1 10.4 5.7 9.8 8.3 5.8 6.2 8.7 9.1 7.3 7.7 10.0 5.5 6.2 5.7 8.9 11.1 21.1 13.0 10.2 10.2 13.8 11.0 15.3 13.4 RNF169 KIAA1991 ENSG00000166439 "Ring finger protein 169" Q8NCN4 11 74748868-74842413 "Enzymes, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038505, HPA046138, HPA058368" Uncertain Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" "Nucleoplasm, Nuclear bodies" Cytosol "HPA038505: , HPA046138: , HPA058368: " "unprognostic (1.71e-1)" "unprognostic (4.18e-2)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (3.86e-2)" "unprognostic (3.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (2.68e-1)" "unprognostic (6.47e-2)" "prognostic unfavourable (8.04e-4)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (3.23e-1)" "unprognostic (2.34e-1)" "unprognostic (9.55e-3)" "unprognostic (1.21e-1)" 12.3 7.0 12.0 11.6 14.0 23.1 12.0 22.6 15.6 13.1 11.2 12.2 6.3 7.4 14.2 8.2 20.6 10.7 10.8 9.2 12.6 5.9 8.9 9.3 16.9 11.3 15.4 9.1 14.6 10.7 17.5 10.4 8.6 13.9 10.5 10.0 8.4 12.4 8.8 15.0 14.1 10.3 14.2 10.1 12.6 10.3 7.2 14.9 12.6 11.5 7.4 12.5 13.1 15.8 0.6 0.8 5.0 1.9 1.2 1.6 0.6 8.1 6.3 7.6 7.5 5.0 6.6 3.1 6.4 6.1 7.2 6.3 10.5 6.2 14.6 6.6 7.7 7.9 10.3 7.7 9.5 7.3 6.6 10.1 11.6 4.1 5.7 5.3 8.5 6.1 6.1 8.2 18.7 11.6 8.9 11.8 7.2 6.9 9.1 9.6 3.0 4.1 8.6 18.2 8.0 4.6 8.6 3.4 6.2 8.7 6.6 13.9 8.2 6.9 7.7 12.0 10.1 7.5 5.7 8.6 4.5 17.4 2.4 5.9 6.9 2.8 1.9 1.5 1.6 1.1 1.2 0.3 1.5 0.9 0.8 0.6 1.1 0.9 5.0 1.2 1.0 0.8 1.2 0.6 12.0 14.0 22.6 15.6 12.6 5.9 15.4 9.1 13.9 14.9 RNF170 "ADSA, DKFZP564A022, SNAX1" ENSG00000120925 "Ring finger protein 170" Q96K19 8 42849637-42897290 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050931, HPA054621" Uncertain "HPA050931: , HPA054621: " "unprognostic (3.06e-2)" "unprognostic (4.20e-1)" "unprognostic (9.54e-2)" "unprognostic (6.37e-2)" "unprognostic (4.59e-2)" "unprognostic (2.84e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.59e-1)" "unprognostic (3.03e-2)" "unprognostic (1.61e-3)" "unprognostic (4.13e-3)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (2.13e-1)" 8.9 13.6 14.3 8.7 17.0 2.2 13.0 15.3 18.8 8.6 10.9 17.5 15.0 10.2 9.8 15.6 14.5 9.7 9.5 8.1 13.7 14.3 17.0 19.4 9.3 8.4 15.7 18.2 13.4 10.8 15.5 16.6 19.0 19.7 11.5 11.7 12.5 12.0 11.5 10.5 14.9 11.3 7.9 21.8 8.8 10.6 7.8 14.2 5.5 29.4 8.0 9.6 10.4 10.6 8.5 11.1 2.6 7.2 5.6 8.0 5.9 6.8 11.2 11.5 5.8 18.8 19.4 6.9 8.3 11.5 7.8 8.5 5.3 22.5 8.4 10.1 7.8 5.9 6.1 8.3 6.7 5.7 6.5 9.7 5.0 5.6 10.5 1.2 7.0 16.8 12.9 5.9 12.4 8.4 8.7 10.0 12.5 2.0 10.2 5.7 5.4 4.0 5.4 15.3 4.7 12.6 6.7 3.0 9.0 7.8 5.6 13.9 14.6 5.6 12.1 8.5 3.7 11.2 2.6 16.2 15.4 9.4 11.5 4.1 8.5 1.7 7.2 2.6 4.0 7.1 5.6 8.5 6.3 6.9 10.7 5.1 7.7 5.5 0.7 5.6 6.5 11.1 8.0 5.9 14.3 17.0 15.3 18.8 13.7 14.3 15.7 18.2 19.7 14.2 RNF180 ENSG00000164197 "Ring finger protein 180" Q86T96 5 64165844-64372869 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 54.0" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 24.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006897 Approved Approved Cytosol Cytosol "HPA006897: AB_1856348" "unprognostic (7.46e-2)" "unprognostic (3.90e-3)" "unprognostic (3.19e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (2.72e-1)" "unprognostic (5.57e-2)" "unprognostic (2.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (3.68e-2)" "prognostic favourable (6.81e-5)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.81e-2)" "unprognostic (9.81e-3)" 8.1 8.1 9.9 3.1 12.8 1.6 6.3 6.0 13.0 10.1 7.1 5.5 20.1 3.4 12.7 11.8 6.9 8.1 7.3 10.4 7.4 10.6 12.4 7.2 6.1 3.4 9.4 9.3 12.0 6.6 54.0 16.1 2.0 10.7 11.5 3.0 11.3 7.3 16.4 4.4 6.6 3.2 15.0 11.0 5.1 5.0 8.1 7.1 0.0 20.6 2.5 2.4 10.9 7.9 2.4 1.0 4.2 1.8 2.0 4.2 0.3 0.0 0.1 1.3 0.0 0.0 0.0 0.3 1.1 0.5 1.1 0.6 0.0 0.1 0.0 0.1 0.8 0.2 0.0 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.2 0.1 2.6 0.0 0.1 0.0 0.0 0.0 2.1 0.4 0.0 0.0 0.5 1.3 0.1 3.3 24.9 1.8 0.3 0.3 0.1 0.0 0.3 0.0 1.3 0.1 0.1 0.0 3.2 0.1 2.8 0.0 0.0 0.0 0.5 0.0 3.5 3.0 1.8 4.2 1.9 0.6 2.5 1.4 3.0 3.2 0.6 2.4 4.2 3.9 2.6 2.0 0.8 1.0 1.8 0.3 9.9 12.8 6.0 11.7 7.4 10.6 9.4 9.3 10.7 7.1 RNF181 HSPC238 ENSG00000168894 "Ring finger protein 181" Q9P0P0 2 85595725-85597613 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046112, HPA062121" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA046112: , HPA062121: " "unprognostic (3.79e-1)" "unprognostic (8.31e-2)" "unprognostic (5.08e-2)" "unprognostic (2.05e-1)" "unprognostic (3.24e-1)" "unprognostic (1.67e-2)" "unprognostic (3.12e-1)" "unprognostic (2.22e-2)" "unprognostic (3.22e-2)" "unprognostic (5.85e-2)" "unprognostic (1.11e-1)" "unprognostic (4.96e-2)" "prognostic unfavourable (1.06e-6)" "unprognostic (3.24e-1)" "unprognostic (2.04e-1)" "prognostic favourable (4.59e-5)" "unprognostic (1.49e-2)" 32.9 41.5 42.2 26.4 36.2 32.8 40.4 19.0 38.7 34.4 40.5 33.0 36.0 34.5 28.1 44.5 40.2 33.3 34.8 52.4 34.5 32.9 57.8 85.1 36.0 33.1 41.2 29.3 31.6 85.1 21.8 20.2 50.7 36.0 34.2 35.4 32.1 42.1 45.7 47.0 30.4 46.5 33.2 42.2 37.2 35.7 36.3 31.3 31.0 43.7 39.2 42.6 43.8 29.4 53.2 80.2 78.6 94.7 39.3 54.4 83.3 32.2 32.7 25.5 27.6 26.1 32.3 41.2 27.3 53.8 58.3 55.4 49.9 34.3 30.8 53.7 40.5 30.3 22.0 43.7 62.7 35.0 27.1 23.4 16.9 59.9 45.8 25.9 32.1 33.7 58.1 38.8 65.0 48.4 27.4 32.1 78.6 51.7 24.4 60.3 17.8 49.4 26.1 53.6 43.7 54.4 30.1 15.2 20.1 23.1 33.6 44.8 33.3 34.3 41.8 28.6 20.4 57.2 38.9 44.8 37.3 38.6 44.7 39.1 25.1 40.4 94.7 71.6 40.7 69.3 37.7 53.2 42.6 39.1 71.0 44.3 36.7 36.8 78.6 39.3 51.8 80.2 54.4 83.3 42.2 36.2 19.0 38.7 34.5 32.9 41.2 29.3 36.0 31.3 RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980302 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.9;brain: 17.6" "Cell line enhanced" "Detected in many" "HeLa: 36.3;RPTEC TERT1: 29.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" Nucleoplasm "HPA012309: AB_1856349" "unprognostic (1.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic unfavourable (4.66e-5)" "unprognostic (6.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (6.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (9.33e-5)" "unprognostic (6.66e-3)" "unprognostic (1.33e-3)" "unprognostic (1.26e-1)" 1.2 0.7 7.6 0.6 6.2 12.9 1.2 16.6 17.6 1.2 0.7 7.5 2.0 0.8 1.6 2.5 1.0 2.7 0.9 1.0 11.0 7.3 2.6 0.5 5.7 0.8 6.8 8.5 1.1 3.6 0.5 2.0 2.9 14.3 0.9 0.6 2.2 1.9 4.7 0.9 0.8 1.1 1.0 5.1 0.5 0.6 7.0 2.9 0.0 3.0 0.0 0.4 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.7 5.2 0.0 1.8 2.2 0.3 2.6 3.6 7.4 7.1 0.1 0.0 0.0 0.0 2.8 0.0 6.1 0.0 13.5 0.0 2.0 0.1 36.3 0.0 0.0 0.0 0.0 1.2 0.0 11.3 0.1 0.1 0.2 0.0 5.1 0.0 0.0 0.9 2.9 10.1 1.5 1.2 0.4 29.1 0.0 6.3 6.0 0.2 0.0 10.2 0.0 1.0 2.7 9.0 1.9 0.1 6.0 0.0 0.0 0.0 6.1 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 6.2 16.6 12.1 11.0 7.3 6.8 8.5 14.3 2.9 RNF183 MGC4734 ENSG00000165188 "Ring finger protein 183" Q96D59 9 113297093-113303376 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 19.0;kidney: 9.5" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 20.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA057675 Uncertain "HPA057675: " "unprognostic (1.23e-2)" "unprognostic (3.17e-1)" "unprognostic (1.11e-1)" "prognostic favourable (7.95e-6)" "unprognostic (2.56e-1)" "unprognostic (1.75e-2)" "unprognostic (1.54e-3)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.98e-1)" "prognostic favourable (3.51e-4)" "unprognostic (5.50e-2)" "unprognostic (8.84e-2)" "unprognostic (9.61e-2)" "unprognostic (2.53e-3)" 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 1.9 0.2 0.2 1.2 19.0 5.1 1.2 6.2 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.8 0.3 6.9 0.2 0.0 0.1 0.1 0.0 0.0 0.0 3.7 4.3 0.1 0.0 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNF187 "RACO-1, RACO1" ENSG00000168159 "Ring finger protein 187" Q5TA31 1 228487061-228495766 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 8.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030098 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA030098: AB_10602923" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "prognostic unfavourable (2.83e-4)" "unprognostic (4.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.93e-2)" "unprognostic (3.46e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (5.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.92e-3)" "unprognostic (1.59e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" 15.7 30.3 25.6 12.5 28.1 12.3 10.3 33.2 54.7 11.4 10.7 15.5 12.5 14.7 12.9 12.2 18.0 14.2 14.5 17.7 25.2 24.9 16.2 20.4 11.5 9.8 20.2 29.3 20.2 19.4 22.3 16.4 8.8 22.7 15.0 6.6 12.3 30.3 12.6 55.5 15.5 13.2 8.6 16.3 19.0 14.2 9.5 11.4 11.1 27.9 19.4 11.2 10.0 13.1 2.0 1.7 8.7 2.1 1.0 2.3 0.6 9.3 7.0 4.9 10.3 5.4 3.5 9.5 7.8 4.8 4.9 3.7 3.6 6.5 21.2 16.3 8.9 7.4 6.2 6.6 1.8 9.6 8.0 6.4 5.2 4.6 14.7 7.3 12.6 6.1 11.8 3.8 5.1 4.3 10.2 41.5 3.5 5.2 11.6 6.5 11.0 7.2 9.9 4.5 20.0 3.5 5.9 10.9 11.0 7.9 16.5 21.0 11.6 17.5 9.9 6.1 6.3 6.6 7.4 75.5 22.6 11.6 16.4 7.7 10.2 0.0 1.1 8.7 1.3 2.1 1.5 1.2 1.5 2.3 1.4 2.0 1.4 1.2 0.3 1.0 1.4 1.7 1.3 0.6 25.6 28.1 33.2 47.3 25.2 24.9 20.2 29.3 22.7 11.4 RNF19A "DKFZp566B1346, dorfin, RNF19" ENSG00000034677 "Ring finger protein 19A, RBR E3 ubiquitin protein ligase" Q9NV58 8 100257060-100336218 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011455, HPA023652" Approved "CAB011455: AB_2180446, HPA023652: AB_1847836" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.84e-1)" "unprognostic (7.09e-2)" "unprognostic (3.36e-1)" "unprognostic (2.12e-2)" "unprognostic (7.96e-2)" "unprognostic (8.92e-2)" "unprognostic (1.13e-1)" "unprognostic (5.97e-2)" "unprognostic (5.20e-2)" "unprognostic (2.99e-1)" "prognostic unfavourable (7.99e-5)" "unprognostic (8.44e-2)" "unprognostic (8.19e-2)" "unprognostic (2.02e-1)" "prognostic favourable (3.28e-5)" 28.2 13.8 30.2 21.8 20.8 34.9 26.7 16.3 29.5 40.6 22.8 26.4 11.4 17.0 29.4 19.0 17.6 24.7 30.8 20.1 28.7 16.1 23.0 33.9 28.4 35.2 19.7 25.2 24.8 20.3 14.5 15.7 18.6 23.6 20.7 19.2 11.5 19.8 14.2 23.0 26.6 38.5 32.7 30.1 22.7 21.5 35.4 27.7 25.1 17.0 14.7 29.5 33.9 23.7 13.5 11.4 17.6 10.5 4.8 14.4 4.5 8.4 5.4 4.8 5.5 9.1 7.9 6.2 7.6 7.3 7.2 6.6 2.9 5.6 5.0 14.0 7.8 6.0 3.7 5.6 9.9 21.1 3.1 8.4 25.2 4.2 7.6 1.6 5.4 7.8 8.6 5.8 10.9 11.1 4.6 58.8 7.1 4.2 7.6 2.7 1.7 5.1 3.1 3.3 9.8 19.8 13.3 3.8 8.2 7.9 4.8 7.3 4.2 6.5 11.0 8.4 6.7 6.2 4.6 28.6 18.3 3.4 5.5 5.6 5.0 17.6 7.5 6.5 14.4 5.6 9.0 13.5 11.8 10.8 4.6 12.7 6.1 8.8 16.6 4.8 10.5 11.4 12.0 4.5 30.2 20.8 16.3 29.5 28.7 16.1 19.7 25.2 23.6 27.7 RNF19B "FLJ90005, IBRDC3" ENSG00000116514 "Ring finger protein 19B" Q6ZMZ0 1 32936445-32964685 "Enzymes, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 54.7" "Cell line enhanced" "Detected in all" "Daudi: 38.4;Karpas-707: 46.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.1" "Lineage enriched" "Detected in many" 8 "granulocytes: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049587 Approved Approved Cytosol Cytosol "HPA049587: " "unprognostic (2.83e-2)" "unprognostic (1.77e-2)" "unprognostic (1.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "prognostic favourable (3.39e-4)" "prognostic unfavourable (5.41e-6)" "unprognostic (8.78e-2)" "unprognostic (5.02e-1)" "unprognostic (1.69e-1)" "unprognostic (9.85e-2)" "unprognostic (1.38e-1)" "prognostic favourable (4.39e-5)" "unprognostic (2.58e-2)" "unprognostic (4.93e-2)" "unprognostic (3.30e-1)" "unprognostic (1.23e-2)" 8.6 11.3 8.0 13.1 10.5 36.4 12.0 14.1 14.1 9.9 13.2 10.1 4.8 14.1 10.8 6.9 23.3 7.9 10.1 8.5 6.0 7.2 12.0 6.5 13.8 12.9 9.6 9.3 7.1 7.0 6.4 5.7 9.4 10.2 7.4 15.3 9.0 10.8 5.7 10.2 13.6 15.5 10.6 8.0 9.0 7.4 54.7 8.3 6.8 8.2 11.1 16.7 11.3 12.8 1.3 1.3 16.1 2.0 0.8 1.6 0.7 6.6 5.1 4.4 4.0 2.7 3.8 29.3 3.0 3.8 5.6 6.0 5.9 19.9 38.4 5.3 4.0 9.5 5.4 7.3 5.1 14.1 3.5 3.3 4.0 5.9 8.6 5.0 7.0 3.1 13.7 12.2 15.1 11.7 4.1 46.2 5.4 2.1 3.3 6.3 7.0 5.8 4.5 6.3 3.9 4.3 9.6 7.0 3.5 9.8 3.4 21.9 2.8 7.4 12.7 3.0 4.2 7.7 5.3 11.1 5.6 13.6 4.4 5.2 4.5 5.3 2.0 3.5 1.6 1.8 1.2 1.2 1.4 0.8 1.3 1.3 0.4 0.6 16.1 0.8 1.5 0.6 1.5 0.7 8.0 10.5 14.1 14.1 6.0 7.2 9.6 9.3 10.2 8.3 RNF2 "BAP-1, BAP1, DING, HIPI3, RING1B, RING2" ENSG00000121481 "Ring finger protein 2" Q99496 1 185045364-185102608 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026803 Uncertain Enhanced "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA026803: AB_10602086" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "unprognostic (1.35e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.08e-5)" "unprognostic (5.85e-2)" "unprognostic (3.56e-3)" "unprognostic (1.62e-2)" "unprognostic (2.01e-2)" "unprognostic (5.51e-2)" "prognostic unfavourable (1.94e-7)" "unprognostic (2.08e-1)" "unprognostic (5.51e-2)" "unprognostic (9.89e-3)" "unprognostic (2.52e-1)" 17.8 15.0 14.3 13.9 12.4 15.3 29.7 15.6 23.6 16.6 12.0 7.8 20.7 10.4 16.2 12.6 15.2 11.5 13.1 12.0 16.0 13.1 13.7 11.1 16.7 20.7 9.4 10.4 19.9 15.0 12.3 26.5 28.4 11.4 13.2 13.5 10.1 17.3 20.6 13.1 12.5 9.8 14.8 11.2 16.2 12.2 27.8 9.4 17.2 15.1 11.5 16.1 17.6 16.9 14.7 19.9 20.6 22.1 17.4 19.4 12.0 13.9 7.7 28.5 11.3 8.1 13.9 27.1 9.9 12.6 15.7 12.6 12.3 23.4 4.2 12.4 12.1 4.9 19.5 14.3 19.1 12.2 10.2 22.5 4.7 10.7 11.9 23.0 12.7 13.0 8.8 12.8 16.5 15.7 17.8 10.0 11.3 8.7 19.9 6.8 38.2 4.2 22.9 17.7 4.0 11.9 9.9 8.4 14.4 6.9 4.2 20.2 8.8 12.4 11.1 11.3 14.7 10.7 12.6 16.5 10.7 15.6 7.0 10.9 12.6 19.3 17.0 20.6 13.5 21.1 19.4 14.6 12.5 12.6 19.9 14.7 12.8 12.6 7.9 17.4 22.1 10.0 13.2 12.0 14.3 12.4 15.6 23.6 16.0 13.1 9.4 10.4 11.4 9.4 RNF20 "BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779" ENSG00000155827 "Ring finger protein 20" Q5VTR2 9 101533851-101563344 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012478, HPA051773" Supported Enhanced Nucleoplasm Nucleoplasm "CAB012478: , HPA051773: " "unprognostic (7.02e-2)" "unprognostic (2.21e-1)" "unprognostic (9.04e-2)" "unprognostic (2.03e-1)" "unprognostic (3.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (2.90e-1)" "unprognostic (2.01e-1)" "unprognostic (5.47e-2)" "unprognostic (7.27e-3)" "unprognostic (1.60e-1)" "prognostic favourable (1.64e-6)" "unprognostic (2.72e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-1)" "unprognostic (9.54e-3)" 16.4 17.1 24.6 17.0 24.9 12.1 17.7 24.4 26.3 18.6 16.4 27.7 15.9 10.1 18.3 18.7 20.4 19.1 13.2 24.1 22.3 22.1 20.5 14.4 14.9 15.5 25.2 20.7 21.1 19.5 31.5 23.1 15.1 30.0 21.6 16.1 16.8 16.2 17.7 32.0 16.3 12.5 23.6 28.8 17.0 13.9 28.2 25.8 21.2 22.0 15.3 18.6 21.1 19.0 13.0 12.5 21.0 23.5 13.8 18.6 10.4 9.5 24.4 14.1 15.4 17.4 13.8 12.0 16.8 13.5 16.8 14.8 14.8 10.2 21.2 9.0 12.9 24.4 16.3 14.2 17.3 22.2 7.5 11.4 22.3 14.8 12.8 19.5 13.7 13.5 15.3 14.8 19.3 9.8 10.8 12.6 18.2 12.5 15.1 5.2 31.1 12.4 14.6 48.8 10.5 6.9 9.2 15.1 19.0 23.7 12.7 13.8 11.4 9.2 13.9 15.6 15.7 11.1 14.0 13.6 42.0 11.7 13.8 7.4 18.9 21.0 12.7 19.1 18.6 17.5 14.0 13.0 15.4 13.9 12.5 11.2 16.2 14.9 13.9 13.8 23.5 7.9 11.9 10.4 24.6 24.9 24.4 26.3 22.3 22.1 25.2 20.7 30.0 25.8 RNF213 "C17orf27, KIAA1554, KIAA1618, MYMY2, NET57" ENSG00000173821 "Ring finger protein 213" Q63HN8 17 80260866-80398786 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Ubl conjugation pathway" "Hydrolase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003347, HPA026790" Approved Supported Cytosol Cytosol "HPA003347: AB_1079204, HPA026790: AB_10602296" "unprognostic (8.98e-2)" "unprognostic (1.60e-1)" "unprognostic (8.97e-3)" "prognostic unfavourable (4.65e-5)" "unprognostic (7.39e-2)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.85e-1)" "unprognostic (1.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-3)" "unprognostic (8.92e-2)" "unprognostic (1.13e-2)" "unprognostic (1.40e-1)" "unprognostic (4.56e-2)" 17.0 15.1 7.4 16.9 10.3 22.4 10.2 4.7 7.5 11.0 12.2 15.6 14.9 8.5 16.6 13.0 13.2 9.7 12.1 8.5 7.8 7.8 17.1 11.6 15.4 17.9 10.9 5.6 11.5 9.0 41.1 11.4 15.1 10.0 11.2 8.0 12.3 11.7 12.5 9.0 8.7 14.8 13.6 14.3 17.0 10.6 5.9 8.7 24.5 15.9 7.5 18.2 13.6 15.4 7.2 13.9 37.9 9.6 11.4 12.1 1.8 16.1 28.7 2.9 2.0 10.5 16.1 2.2 4.1 8.9 18.5 15.8 3.0 7.5 1.0 3.5 8.5 9.4 3.9 5.3 6.3 36.5 1.7 2.5 11.6 5.3 4.5 2.6 2.6 8.8 3.6 10.4 4.5 14.2 4.6 6.0 6.9 3.9 10.5 1.1 2.1 6.6 7.2 6.7 1.2 5.1 14.0 2.8 3.9 9.9 21.1 7.5 4.8 3.3 18.3 10.3 8.2 6.0 4.2 2.6 2.4 2.9 7.7 3.1 3.7 6.9 9.6 4.2 12.1 8.0 8.1 6.2 8.6 9.7 2.3 7.2 6.9 8.5 37.9 11.4 6.9 13.9 6.4 1.8 7.4 10.3 4.7 7.5 7.8 7.8 10.9 5.6 10.0 8.7 RNF216 "TRIAD3, UBCE7IP1, ZIN" ENSG00000011275 "Ring finger protein 216" Q9NWF9 7 5620047-5781739 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease mutation, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018955, HPA021123" Supported Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA018955: AB_1858500, HPA021123: AB_1858501" "unprognostic (3.31e-2)" "unprognostic (4.24e-2)" "unprognostic (1.28e-2)" "unprognostic (1.58e-2)" "unprognostic (1.81e-2)" "unprognostic (1.56e-1)" "prognostic unfavourable (2.26e-4)" "unprognostic (2.35e-1)" "unprognostic (2.40e-1)" "unprognostic (1.40e-2)" "prognostic favourable (6.24e-5)" "unprognostic (2.88e-2)" "unprognostic (9.01e-2)" "unprognostic (3.49e-1)" "unprognostic (1.73e-2)" "unprognostic (1.06e-2)" "unprognostic (3.69e-3)" 16.9 14.9 22.0 18.8 24.8 22.2 18.4 33.5 27.8 17.8 26.9 22.0 13.4 11.5 26.9 13.3 18.7 19.6 14.2 29.1 20.5 17.4 12.7 11.8 14.9 23.8 23.8 14.8 25.6 21.3 23.2 24.9 14.6 20.4 17.7 11.8 18.9 16.2 21.5 22.5 15.1 20.1 25.0 18.7 23.3 18.3 34.3 26.3 18.5 19.8 9.6 24.1 17.7 30.7 8.8 6.7 24.5 8.4 10.0 9.7 6.5 14.4 15.6 12.8 21.8 15.3 13.3 8.8 15.5 16.3 16.1 14.9 11.3 8.3 12.7 8.0 17.3 10.4 13.3 10.9 13.2 7.9 11.6 9.8 9.5 11.4 18.4 16.0 16.8 13.7 14.0 12.3 15.1 12.7 19.6 8.9 17.8 22.2 6.0 25.5 17.6 13.0 15.3 18.1 7.1 9.6 12.2 9.8 15.6 9.8 24.6 8.8 9.7 16.4 13.8 16.3 29.4 16.6 13.9 7.2 5.4 10.3 12.2 14.9 25.9 1.3 7.7 24.5 9.0 8.4 9.0 7.3 7.9 6.7 6.7 8.8 9.7 9.1 13.1 10.0 7.7 5.4 7.0 6.5 22.0 24.8 33.5 27.8 20.5 17.4 23.8 14.8 20.4 26.3 RNF217 "C6orf172, dJ84N20.1, IBRDC1, MGC26996" ENSG00000146373 "Ring finger protein 217" Q8TC41 6 124962545-125092633 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 63.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 1.9;myeloid DC: 1.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029598 Uncertain "HPA029598: AB_10602297" "unprognostic (2.96e-2)" "unprognostic (2.34e-3)" "unprognostic (8.07e-2)" "unprognostic (8.62e-2)" "unprognostic (1.94e-1)" "unprognostic (2.06e-2)" "unprognostic (1.06e-1)" "unprognostic (7.22e-3)" "unprognostic (4.94e-2)" "unprognostic (6.69e-2)" "unprognostic (2.47e-1)" "unprognostic (2.61e-1)" "prognostic unfavourable (4.60e-5)" "unprognostic (8.29e-4)" "unprognostic (2.16e-1)" "unprognostic (7.52e-2)" "prognostic unfavourable (1.92e-4)" 9.6 3.5 3.3 4.2 4.7 10.5 14.6 3.8 3.5 8.0 7.7 5.7 6.4 2.3 5.9 5.6 6.2 7.5 12.1 6.5 3.8 1.7 2.5 6.3 7.3 3.7 4.3 2.9 11.5 3.8 63.3 4.0 12.0 3.4 6.4 2.3 6.0 6.0 6.9 10.1 10.9 3.1 13.0 2.3 2.6 4.5 7.4 5.7 0.1 7.4 3.6 1.6 8.7 13.6 0.0 1.2 0.6 1.9 0.3 0.2 0.3 4.1 4.2 1.5 0.5 5.4 2.1 8.5 5.7 7.7 3.9 5.1 0.0 3.9 0.0 7.9 5.4 6.0 0.9 5.1 5.5 0.0 4.8 2.3 6.3 1.3 5.2 0.0 0.2 5.9 4.7 2.9 8.6 4.4 11.6 0.0 6.8 0.0 0.0 0.0 1.3 1.1 0.1 5.9 0.0 4.0 1.9 0.7 0.0 2.5 0.6 2.1 4.1 0.6 6.9 3.2 10.3 0.0 12.1 0.0 0.0 0.0 2.4 0.0 3.8 0.6 1.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.3 0.3 0.0 0.0 0.3 3.3 4.7 3.8 3.5 3.8 1.7 4.3 2.9 3.4 5.7 RNF220 "C1orf164, FLJ10597" ENSG00000187147 "Ring finger protein 220" Q5VTB9 1 44405194-44651724 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 57.4" "Cell line enhanced" "Detected in all" "U-937: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027577, HPA027578" Uncertain Approved Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA027577: , HPA027578: AB_10601482" "unprognostic (3.12e-2)" "unprognostic (1.24e-1)" "unprognostic (3.49e-2)" "unprognostic (2.56e-1)" "unprognostic (2.94e-2)" "unprognostic (6.96e-3)" "prognostic unfavourable (2.35e-6)" "unprognostic (1.55e-1)" "unprognostic (8.47e-2)" "unprognostic (2.13e-1)" "unprognostic (2.14e-3)" "unprognostic (2.96e-2)" "prognostic unfavourable (5.12e-4)" "unprognostic (1.51e-2)" "unprognostic (1.98e-1)" "unprognostic (1.37e-3)" "unprognostic (6.46e-2)" 9.8 7.4 20.9 9.6 38.5 12.7 6.7 12.6 40.1 5.4 9.2 40.7 2.7 10.7 8.0 8.8 6.0 9.3 4.5 9.2 33.4 20.9 7.4 5.1 7.4 7.6 49.8 19.8 9.5 8.1 7.0 5.7 8.7 25.8 7.7 5.9 4.2 9.3 7.1 28.4 8.7 8.8 8.0 57.4 7.9 7.6 7.0 49.6 5.0 7.3 4.6 8.0 7.9 5.6 3.6 6.6 2.8 2.3 1.9 4.3 1.4 5.9 2.8 12.3 4.2 4.8 4.4 9.3 7.1 6.5 5.5 8.1 4.9 5.9 11.6 6.3 5.6 3.9 13.8 5.8 7.5 14.4 12.2 16.0 8.9 8.3 7.8 11.3 8.2 4.8 13.3 6.1 9.8 3.1 11.7 5.8 3.4 4.1 11.1 8.6 13.4 6.5 9.4 7.3 8.3 3.5 3.7 5.6 6.9 6.0 4.2 8.6 3.1 20.0 4.8 5.8 6.2 5.4 13.1 13.2 12.7 8.4 4.8 36.5 3.5 2.4 2.3 2.8 3.2 1.8 2.4 2.4 1.0 4.3 3.4 3.6 1.9 1.7 1.5 1.9 1.3 6.6 3.2 1.4 20.9 38.5 12.6 30.8 33.4 20.9 49.8 19.8 25.8 49.6 RNF25 "AO7, FLJ13906" ENSG00000163481 "Ring finger protein 25" Q96BH1 2 218663864-218672411 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036420, HPA036421" Uncertain Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA036420: , HPA036421: AB_10669604" "unprognostic (3.22e-2)" "unprognostic (7.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (6.58e-4)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (3.46e-1)" "unprognostic (2.04e-3)" "unprognostic (8.82e-2)" "unprognostic (1.26e-3)" "unprognostic (2.50e-1)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.69e-2)" 13.4 12.7 13.9 11.1 16.1 6.2 13.7 13.4 27.6 17.3 13.3 17.1 9.8 4.3 16.6 16.2 12.2 16.8 11.8 17.2 13.1 16.5 13.7 15.6 11.9 12.1 12.1 11.6 17.8 13.0 19.3 14.8 17.7 15.4 14.7 9.0 15.3 13.6 17.9 16.9 15.7 10.3 16.0 10.0 12.9 11.8 18.4 9.1 15.3 16.8 12.7 16.8 14.0 11.8 13.3 8.2 23.3 11.2 14.8 15.0 13.9 5.9 7.6 6.9 8.0 10.5 6.4 7.4 6.7 17.0 23.2 21.7 12.6 4.0 3.9 5.4 14.2 5.4 7.9 13.2 10.1 4.3 10.9 5.4 5.6 11.9 12.9 4.7 5.9 14.2 12.4 21.1 14.2 12.7 9.0 6.2 14.9 16.9 5.3 5.8 10.9 8.7 7.5 4.3 5.8 14.2 6.3 7.0 7.9 5.2 5.8 10.0 6.9 8.8 7.3 13.2 6.3 5.1 9.6 5.3 4.2 6.6 11.1 5.9 8.0 23.3 10.6 14.9 13.9 10.3 12.6 11.9 13.7 13.6 8.2 13.3 15.0 11.7 8.9 14.8 11.2 7.4 11.5 13.9 13.9 16.1 13.4 27.6 13.1 16.5 12.1 11.6 15.4 9.1 RNF26 MGC2642 ENSG00000173456 "Ring finger protein 26" Q9BY78 11 119334527-119337313 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027620 Uncertain Approved Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "HPA027620: AB_1856356" "unprognostic (9.23e-3)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (3.40e-1)" "unprognostic (1.07e-2)" "prognostic unfavourable (3.19e-4)" "unprognostic (2.14e-2)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (7.24e-3)" "unprognostic (6.22e-2)" "prognostic favourable (3.45e-6)" "unprognostic (9.61e-2)" "unprognostic (3.50e-2)" "unprognostic (4.41e-2)" "prognostic unfavourable (7.73e-4)" 19.0 21.5 13.6 15.4 21.6 25.6 16.9 18.4 38.9 19.8 22.0 17.6 14.5 20.3 31.2 15.6 26.0 24.4 19.8 15.1 17.1 13.8 22.3 28.7 17.3 17.5 15.0 16.6 25.6 18.5 31.4 14.3 27.5 27.2 19.2 18.2 20.2 20.0 28.5 17.6 19.8 21.4 27.0 14.3 19.8 24.3 27.6 13.0 26.7 20.6 14.0 21.1 25.8 18.1 13.8 14.2 7.1 15.5 9.8 16.7 16.2 15.6 17.3 16.2 19.1 16.0 12.7 17.3 17.0 18.4 19.9 15.8 29.2 32.8 13.8 23.6 20.2 28.5 23.0 25.6 12.5 16.5 12.6 36.4 8.1 24.1 12.3 15.2 15.2 13.1 13.2 24.8 22.4 15.1 17.6 21.7 13.6 34.1 13.9 15.8 16.2 22.2 14.5 16.7 11.0 12.2 11.3 11.6 11.2 13.7 17.5 4.5 39.5 12.8 9.9 24.1 16.1 12.6 15.5 5.2 8.5 0.1 8.0 25.8 18.7 7.1 15.5 3.9 16.7 14.5 11.0 9.0 12.7 14.5 14.2 13.8 14.5 12.4 1.1 9.8 14.1 8.1 6.6 16.2 13.6 21.6 18.4 38.9 17.1 13.8 15.0 16.6 27.2 13.0 RNF31 "FLJ10111, FLJ23501, HOIP, Paul, ZIBRA" ENSG00000092098 "Ring finger protein 31" Q96EP0 14 24146683-24160661 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB009063, HPA048745" Approved Approved Cytosol Cytosol "CAB009063: AB_2127706, HPA048745: " "unprognostic (3.58e-2)" "unprognostic (5.22e-2)" "unprognostic (2.51e-2)" "unprognostic (9.05e-2)" "unprognostic (2.52e-1)" "unprognostic (6.24e-2)" "unprognostic (9.09e-3)" "unprognostic (1.55e-2)" "unprognostic (3.11e-3)" "unprognostic (1.96e-2)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (6.21e-3)" "unprognostic (1.15e-1)" "unprognostic (2.59e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-1)" 14.4 18.5 11.7 21.5 17.4 20.0 15.1 20.0 26.4 17.7 17.3 18.4 19.9 13.4 22.4 22.3 15.4 17.4 17.2 14.5 10.7 9.8 17.2 14.8 15.3 19.3 11.0 18.0 20.6 23.6 20.0 19.2 18.7 13.4 16.4 14.1 16.9 19.6 23.1 39.5 29.1 16.1 19.7 9.1 27.3 16.5 21.8 11.0 33.6 17.4 13.1 24.9 16.3 13.5 2.4 4.6 3.8 3.7 2.5 4.8 1.3 4.4 10.3 9.7 12.0 6.6 6.9 19.7 7.8 11.5 15.3 12.2 9.4 11.2 8.8 4.9 11.0 7.6 5.5 11.0 9.1 9.3 4.2 8.2 10.6 20.6 10.8 13.8 14.7 12.5 9.5 6.9 10.9 9.7 4.8 11.7 6.8 13.8 13.0 8.1 5.2 11.3 8.8 7.2 5.6 7.8 18.4 8.6 10.8 7.1 18.9 9.4 6.6 10.2 9.5 10.8 8.2 7.8 7.3 15.6 13.8 8.6 4.1 5.5 10.0 0.0 2.1 1.5 1.9 3.7 4.8 2.4 1.9 2.1 1.8 1.1 2.3 1.3 3.8 2.5 2.1 4.6 3.0 1.3 11.7 17.4 20.0 26.4 10.7 9.8 11.0 18.0 13.4 11.0 RNF34 "FLJ21786, RIF, RIFF" ENSG00000170633 "Ring finger protein 34" Q969K3 12 121400041-121430623 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074151 Supported "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA074151: " "unprognostic (3.54e-1)" "unprognostic (4.83e-2)" "unprognostic (1.90e-1)" "unprognostic (6.10e-2)" "unprognostic (9.92e-2)" "unprognostic (2.55e-2)" "prognostic unfavourable (6.72e-8)" "unprognostic (3.39e-1)" "unprognostic (9.99e-2)" "unprognostic (1.60e-2)" "unprognostic (5.87e-3)" "unprognostic (2.80e-2)" "prognostic unfavourable (4.63e-4)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (5.55e-3)" "prognostic favourable (3.02e-4)" 11.9 10.6 18.2 19.6 23.4 10.4 12.3 25.2 26.9 11.2 17.3 21.5 10.0 17.0 15.0 12.7 14.4 11.7 15.5 16.0 17.6 17.7 10.8 11.1 11.6 27.2 19.3 19.4 14.0 12.2 11.1 17.1 10.2 19.3 10.2 14.2 12.7 12.4 12.9 45.7 13.8 16.0 15.0 21.3 19.4 16.3 20.8 17.2 21.7 12.7 9.1 22.5 16.4 11.5 31.8 16.9 36.5 20.3 29.9 42.8 25.8 18.4 22.4 14.6 15.3 11.6 10.7 18.4 19.7 17.7 19.7 15.1 27.7 7.1 26.6 15.2 21.2 13.4 22.0 12.4 17.6 38.7 13.0 30.8 15.5 25.4 14.0 26.5 21.7 9.5 16.8 17.1 14.9 20.6 23.2 12.5 19.3 14.6 23.3 38.9 18.8 20.4 22.3 19.2 15.6 13.6 22.1 21.7 14.1 24.8 9.3 15.0 16.1 20.2 16.5 17.0 12.3 14.7 15.5 22.2 36.7 29.0 12.1 18.7 17.0 26.9 17.9 36.5 32.4 19.9 33.0 31.8 37.8 34.1 16.9 25.5 32.8 32.6 27.4 29.9 20.3 14.3 42.8 25.8 18.2 23.4 25.2 26.9 17.6 17.7 19.3 19.4 19.3 17.2 RNF38 ENSG00000137075 "Ring finger protein 38" Q9H0F5 9 36336396-36487548 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015853 Approved Supported Nucleoplasm Nucleoplasm "HPA015853: AB_1856365" "unprognostic (2.26e-1)" "unprognostic (2.49e-1)" "unprognostic (1.53e-1)" "unprognostic (8.16e-2)" "unprognostic (6.49e-2)" "unprognostic (3.65e-3)" "unprognostic (3.30e-3)" "unprognostic (1.64e-2)" "unprognostic (1.58e-1)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "prognostic favourable (2.90e-6)" "unprognostic (3.88e-2)" "unprognostic (5.94e-2)" "unprognostic (1.46e-1)" "unprognostic (5.39e-2)" 11.9 8.0 13.1 7.7 14.5 20.3 11.1 18.8 17.0 13.6 14.1 12.2 8.1 6.4 16.3 12.9 10.1 11.7 9.6 9.5 10.0 11.1 12.3 6.8 11.7 14.5 9.2 12.3 24.4 12.8 12.2 5.7 21.2 14.0 15.3 10.1 14.4 10.3 12.8 9.6 8.9 10.2 16.9 8.5 11.4 8.7 46.3 10.0 13.1 14.4 4.3 11.1 16.5 13.5 6.2 4.1 12.2 4.3 8.4 8.7 4.2 9.3 5.3 20.6 12.2 9.5 8.8 20.2 5.8 7.4 7.2 9.5 9.0 5.2 14.1 6.2 11.3 3.7 13.1 6.9 11.2 12.5 5.6 17.0 7.5 8.8 7.4 12.5 15.6 9.0 7.4 9.1 8.8 18.3 3.5 13.6 11.6 3.2 12.8 6.6 13.8 3.8 11.8 9.3 7.8 12.3 10.8 8.6 9.3 6.6 6.7 6.6 6.4 12.8 18.0 6.9 10.5 4.0 6.9 9.0 18.7 10.0 6.3 10.6 8.8 12.2 4.3 7.2 7.2 4.1 6.0 5.8 6.5 7.6 4.1 6.2 7.0 7.0 8.0 8.4 4.1 3.3 8.7 4.2 13.1 14.5 18.8 17.0 10.0 11.1 9.2 12.3 14.0 10.0 RNF4 "RES4-26, SLX5, SNURF" ENSG00000063978 "Ring finger protein 4" P78317 4 2462220-2625320 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022047, HPA049356" Approved Supported "Nucleoplasm,Nuclear bodies,Microtubule ends" "Nucleoplasm, Nuclear bodies" "Microtubule ends" "HPA022047: , HPA049356: " "unprognostic (8.38e-3)" "unprognostic (1.69e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (9.31e-3)" "unprognostic (9.03e-3)" "prognostic unfavourable (6.38e-4)" "unprognostic (1.34e-1)" "unprognostic (6.79e-2)" "unprognostic (2.58e-1)" "unprognostic (5.64e-2)" "unprognostic (1.93e-2)" "unprognostic (6.40e-2)" "unprognostic (4.70e-2)" "unprognostic (8.67e-2)" "unprognostic (1.54e-1)" 28.6 29.1 25.4 32.2 39.4 36.4 28.6 35.9 50.3 28.2 25.1 34.8 28.4 27.0 32.2 28.0 30.3 27.8 27.1 24.6 22.7 22.8 32.3 25.6 27.4 41.9 23.5 23.4 32.1 31.0 31.2 30.0 29.4 36.7 28.5 26.7 29.2 36.1 28.5 26.0 28.5 29.3 31.8 23.1 41.9 28.9 36.8 23.7 50.4 29.3 19.1 51.5 27.7 26.3 36.9 35.3 41.8 39.9 39.7 43.7 45.8 19.8 18.9 19.8 13.8 17.2 18.0 22.1 24.3 27.4 25.9 23.5 21.4 18.8 25.2 14.5 24.5 13.0 20.9 19.0 24.7 11.8 12.6 30.5 19.5 20.4 25.9 21.4 26.7 20.8 23.1 24.0 20.1 23.9 16.1 34.9 26.4 13.6 34.3 29.9 30.4 23.7 25.0 18.8 13.0 17.6 25.4 18.4 17.4 17.0 13.3 16.9 21.0 16.2 19.9 22.6 11.1 21.3 37.2 45.2 60.1 27.9 22.0 23.4 23.4 14.6 29.6 41.8 43.7 39.3 43.7 36.9 37.5 43.0 35.3 27.2 36.2 36.3 32.9 39.7 39.9 23.6 39.9 45.8 25.4 39.4 35.9 50.3 22.7 22.8 23.5 23.4 36.7 23.7 RNF40 "BRE1B, KIAA0661, RBP95, STARING" ENSG00000103549 "Ring finger protein 40" O75150 16 30761745-30776307 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041330, HPA054227" Approved Supported Nucleoplasm Nucleoplasm "HPA041330: AB_10793872, HPA054227: " "unprognostic (1.61e-1)" "unprognostic (1.74e-2)" "unprognostic (3.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.21e-1)" "unprognostic (4.01e-1)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.16e-2)" "unprognostic (1.91e-2)" "prognostic favourable (8.11e-8)" "unprognostic (9.96e-2)" "unprognostic (1.36e-1)" "unprognostic (6.55e-3)" "unprognostic (6.60e-3)" 21.0 25.2 26.4 21.3 26.5 40.8 20.9 36.8 28.2 25.8 21.0 22.0 18.0 20.1 28.4 17.0 25.6 24.4 21.3 22.8 22.2 17.1 20.0 21.2 20.2 21.9 20.9 18.9 30.5 24.4 44.0 21.6 25.3 19.6 21.4 15.1 20.0 27.3 21.1 20.0 25.5 20.3 18.3 18.6 20.0 19.6 43.1 22.8 23.5 26.8 15.4 20.6 22.5 21.4 7.6 12.0 15.0 14.9 9.9 13.3 12.9 20.3 31.9 19.4 18.4 14.8 15.5 21.2 20.8 16.1 24.1 18.8 25.7 19.0 16.2 30.6 17.8 22.1 35.3 18.5 18.9 23.2 41.4 15.8 35.0 26.7 19.8 27.4 18.6 14.4 15.5 30.2 17.1 20.2 34.8 15.5 14.6 34.0 26.1 25.7 20.2 19.3 51.9 21.4 31.2 10.6 18.1 32.4 23.8 16.3 20.9 15.0 32.0 31.2 21.8 27.1 13.8 19.1 23.7 23.1 28.5 32.2 22.5 24.4 27.6 6.2 11.5 14.7 12.9 13.4 13.3 7.6 7.2 9.9 12.0 6.5 5.4 8.3 15.0 9.9 14.9 6.2 6.2 12.9 26.4 26.5 36.8 28.2 22.2 17.1 20.9 18.9 19.6 22.8 RNF41 "NRDP1, SBBI03" ENSG00000181852 "Ring finger protein 41" Q9H4P4 12 56202175-56221933 "Enzymes, Predicted intracellular proteins" "Apoptosis, Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016812 Approved Approved "Nucleoplasm,Nuclear bodies,Midbody ring" "Nucleoplasm, Nuclear bodies" "Midbody ring" "HPA016812: AB_1856370" "unprognostic (1.14e-2)" "unprognostic (6.30e-2)" "unprognostic (4.04e-2)" "unprognostic (6.86e-2)" "unprognostic (9.59e-2)" "unprognostic (8.22e-2)" "prognostic unfavourable (6.49e-4)" "unprognostic (6.93e-2)" "unprognostic (4.18e-2)" "unprognostic (1.67e-1)" "unprognostic (5.80e-2)" "unprognostic (5.90e-2)" "prognostic favourable (2.52e-5)" "unprognostic (1.64e-1)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" 22.2 17.6 18.6 11.8 30.2 12.0 14.3 30.9 47.1 16.2 15.0 16.9 12.3 8.5 16.4 9.7 16.5 17.7 18.0 22.6 17.3 22.4 14.1 10.5 16.5 14.8 15.3 18.2 17.0 16.0 17.9 16.7 14.6 25.3 25.2 13.6 14.6 10.5 15.6 21.2 10.1 10.8 20.3 11.8 13.5 12.2 10.1 12.1 11.3 20.5 10.1 17.0 16.2 11.5 24.6 13.1 41.1 11.5 13.4 12.5 12.3 7.5 11.6 12.6 20.0 26.5 19.3 9.4 25.3 25.1 22.8 18.5 14.2 9.9 14.6 13.5 21.4 8.7 17.0 12.2 16.6 15.2 9.3 19.6 8.3 8.1 55.6 21.4 21.4 24.6 28.7 19.0 33.6 22.1 13.8 15.0 12.6 12.2 12.2 9.6 15.2 13.6 13.3 9.1 8.8 12.1 11.1 23.1 14.0 22.1 12.7 20.0 17.8 25.2 13.3 11.5 12.3 14.8 9.7 10.8 12.4 13.3 13.7 12.9 13.7 21.0 11.5 41.1 12.5 11.4 11.2 22.7 10.6 10.9 13.1 24.6 11.0 11.2 15.8 13.4 11.2 10.2 12.1 12.3 18.6 30.2 30.9 47.1 17.3 22.4 15.3 18.2 25.3 12.1 RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58352500-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 14.9;Hep G2: 29.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.7" "Region enriched" "Detected in many" 7 "cerebellum: 30.6" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008079 Uncertain "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favourable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" 0.4 9.4 2.2 6.2 3.5 1.9 4.5 30.6 4.3 3.4 26.4 0.9 21.3 18.5 1.7 9.1 10.0 3.9 8.1 3.3 1.9 1.3 8.0 7.0 6.1 2.7 0.8 1.1 1.6 13.2 3.0 13.3 8.7 4.1 8.0 16.3 3.8 13.7 19.0 0.5 8.9 29.0 0.9 0.8 0.9 4.9 3.1 0.7 3.0 1.8 5.7 6.6 4.0 4.4 0.9 1.1 1.7 1.8 5.6 3.6 1.2 0.7 10.4 1.9 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 14.9 5.0 4.2 5.3 0.0 2.9 0.4 4.0 0.0 8.8 7.3 3.4 0.5 29.2 0.0 4.2 3.0 0.0 8.2 0.0 1.3 0.0 0.3 3.6 0.0 0.1 2.2 3.9 0.3 0.7 6.9 0.0 2.2 3.7 5.6 1.2 0.3 0.9 0.4 0.3 1.3 1.2 0.0 0.1 1.2 0.0 0.0 3.8 1.7 3.3 0.4 0.4 2.4 1.7 0.2 1.6 3.1 0.8 3.2 0.9 2.5 3.6 0.4 0.9 2.3 3.0 0.8 5.6 1.8 1.1 1.2 1.2 2.2 3.5 30.6 4.3 1.9 1.3 0.8 1.1 4.1 0.7 RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178354-32180793 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: " "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favourable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" 9.8 20.6 19.3 9.0 20.6 10.3 14.0 13.6 16.8 11.3 25.7 17.4 14.7 18.1 12.3 14.6 15.9 16.9 13.9 19.2 16.9 12.0 32.7 38.1 14.7 11.6 16.3 14.2 19.0 19.3 7.2 5.8 23.4 12.3 13.1 19.1 12.2 25.3 15.3 24.5 13.4 36.7 13.7 19.7 10.2 14.2 9.6 9.6 10.8 18.0 14.2 12.5 13.2 9.9 6.7 26.9 7.2 6.4 7.5 7.0 6.5 5.2 6.8 4.6 17.8 5.1 3.5 3.6 2.1 2.7 4.6 5.3 9.1 4.4 6.8 7.7 5.1 4.3 8.6 4.8 4.9 4.2 11.7 5.4 7.7 18.7 6.0 0.0 11.1 3.5 6.5 7.8 5.9 9.3 13.9 7.4 6.7 7.4 6.6 15.6 0.0 2.9 4.5 5.3 9.5 13.1 3.3 4.8 10.0 4.1 4.5 4.6 9.3 19.1 4.2 5.2 5.0 0.0 8.1 4.0 6.1 8.0 3.6 12.1 3.0 5.1 4.6 7.2 7.0 6.4 6.1 6.7 5.7 6.2 6.6 6.0 6.4 6.3 2.4 7.5 4.5 26.9 5.7 6.5 19.3 20.6 13.6 16.8 16.9 12.0 16.3 14.2 12.3 9.6 RNF6 DKFZp686P0776 ENSG00000127870 "Ring finger protein 6" Q9Y252 13 26132115-26222493 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039343, HPA040048" Approved Supported "Nuclear membrane" "Nuclear membrane" "HPA039343: AB_2676456, HPA040048: AB_10672969" "unprognostic (3.22e-1)" "prognostic unfavourable (3.07e-4)" "unprognostic (1.45e-1)" "unprognostic (1.63e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-2)" "unprognostic (1.97e-1)" "unprognostic (4.07e-2)" "unprognostic (7.63e-2)" "unprognostic (6.13e-2)" "unprognostic (1.39e-1)" "unprognostic (4.21e-2)" "unprognostic (2.70e-2)" "unprognostic (8.35e-3)" "unprognostic (1.84e-1)" "unprognostic (7.70e-2)" "unprognostic (8.47e-2)" 16.4 19.8 22.3 15.9 27.5 25.1 24.2 26.6 28.9 13.1 16.4 8.1 20.3 15.5 13.0 13.0 20.9 13.4 12.5 17.9 20.4 17.3 16.9 17.5 14.5 18.4 15.8 22.6 10.9 14.2 17.9 26.3 23.3 16.8 15.2 17.2 8.1 16.1 13.5 24.8 15.5 21.0 14.3 16.7 16.6 15.1 28.7 14.5 23.6 16.1 14.4 20.7 14.1 19.5 13.5 12.5 24.6 15.0 13.3 13.2 9.2 12.6 11.1 4.2 6.2 14.7 11.6 9.5 21.7 17.8 14.1 10.0 13.9 16.3 22.7 10.9 20.6 17.0 11.8 17.6 23.5 21.7 7.4 24.7 9.4 11.9 23.1 25.8 26.1 10.9 34.4 15.8 33.9 14.1 9.5 0.0 21.8 11.3 14.4 15.1 3.4 7.8 11.5 16.4 8.9 17.4 16.7 7.7 4.7 11.6 21.3 20.6 8.1 25.4 18.4 12.2 7.4 16.3 15.5 5.8 5.4 13.6 11.1 14.8 15.9 24.6 10.1 23.7 11.9 13.1 12.8 13.5 13.0 13.2 12.5 9.4 13.2 11.2 7.1 13.3 15.0 6.5 13.1 9.2 22.3 27.5 26.6 28.9 20.4 17.3 15.8 22.6 16.8 14.5 RNF8 KIAA0646 ENSG00000112130 "Ring finger protein 8" O76064 6 37353972-37394738 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050731, HPA064925" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA050731: , HPA064925: " "unprognostic (1.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.39e-2)" "unprognostic (8.20e-2)" "unprognostic (5.17e-2)" "unprognostic (3.99e-2)" "prognostic unfavourable (3.33e-5)" "unprognostic (2.36e-2)" "prognostic unfavourable (1.91e-4)" "unprognostic (2.26e-3)" "unprognostic (3.38e-1)" "prognostic unfavourable (4.99e-5)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (3.41e-2)" "unprognostic (3.66e-3)" "unprognostic (1.09e-1)" 8.0 11.7 13.1 8.2 17.8 8.9 11.5 25.7 18.7 9.2 9.5 10.6 6.8 6.9 13.5 5.7 18.3 12.0 8.8 17.6 13.4 14.8 11.8 7.5 10.8 8.3 12.0 16.0 13.2 6.5 11.9 16.4 10.2 13.7 8.6 8.2 8.0 10.2 11.9 15.2 9.9 8.4 10.7 9.6 7.7 7.6 19.8 13.8 6.6 8.0 9.4 13.3 12.9 15.2 8.8 8.3 2.6 8.1 7.6 10.8 5.5 6.5 3.9 9.5 11.3 7.7 11.1 2.7 6.8 8.4 12.9 14.2 5.8 3.7 8.1 4.2 6.6 6.2 13.2 8.6 13.6 8.5 12.8 14.0 6.9 8.7 4.4 7.4 10.3 5.5 8.3 7.7 9.0 12.4 9.4 2.8 7.4 4.3 9.0 9.2 6.6 5.2 7.1 8.8 5.6 6.6 4.6 18.8 6.3 5.1 5.8 9.4 5.2 7.3 5.6 8.5 7.6 8.0 10.0 8.4 11.1 40.0 4.2 10.6 9.8 1.0 4.6 2.6 10.8 6.0 10.0 8.8 8.1 10.2 8.3 6.0 7.1 9.4 0.6 7.6 8.1 3.6 9.3 5.5 13.1 17.8 25.7 18.7 13.4 14.8 12.0 16.0 13.7 13.8 RNFT1 PTD016 ENSG00000189050 "Ring finger protein, transmembrane 1" Q5M7Z0 17 59952240-59964761 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 45.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013739 Approved Nucleoli Nucleoli "HPA013739: AB_1856382" "unprognostic (1.61e-1)" "unprognostic (2.83e-1)" "prognostic favourable (6.57e-4)" "unprognostic (3.04e-2)" "unprognostic (6.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-2)" "prognostic favourable (7.48e-4)" "unprognostic (5.42e-2)" "unprognostic (3.45e-1)" "unprognostic (8.26e-3)" "unprognostic (9.44e-3)" "unprognostic (1.19e-3)" "unprognostic (1.44e-2)" "unprognostic (2.05e-1)" "prognostic favourable (2.57e-4)" "unprognostic (2.60e-1)" 7.9 6.2 2.8 5.3 4.3 3.8 4.2 5.1 3.7 3.1 4.0 2.4 3.7 5.3 2.7 8.1 4.6 3.2 3.1 4.1 3.1 2.2 4.7 12.0 5.0 4.4 2.9 3.1 3.5 7.5 4.7 6.1 4.4 3.4 4.5 4.8 4.2 5.1 3.0 6.7 2.7 7.6 3.0 3.4 4.1 3.9 45.5 3.0 5.9 6.1 4.3 6.0 5.1 3.7 9.5 10.1 20.2 17.1 8.9 7.7 7.9 4.8 2.2 2.3 3.1 7.6 5.7 4.5 6.2 3.3 4.8 6.0 6.9 1.9 7.2 10.4 5.1 5.6 7.2 4.7 8.4 6.8 7.8 6.0 5.8 6.2 5.6 9.3 9.3 6.3 2.5 4.5 2.0 4.9 17.3 4.4 4.1 6.2 3.8 4.5 0.9 5.1 5.2 17.4 4.1 3.9 3.4 1.4 2.7 8.9 2.1 12.3 10.2 17.8 3.5 9.4 8.4 5.5 5.2 6.5 18.0 4.2 6.5 5.2 4.7 17.3 11.8 20.2 5.6 13.9 7.7 9.5 5.2 6.3 10.1 6.1 6.8 6.1 5.7 8.9 17.1 6.7 6.5 7.9 2.8 4.3 5.1 3.7 3.1 2.2 2.9 3.1 3.4 3.0 RNGTT "hCAP, HCE, HCE1" ENSG00000111880 "RNA guanylyltransferase and 5'-phosphatase" O60942 6 88610272-88963721 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA capping, mRNA processing" "Hydrolase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003750 Approved Approved Nucleoplasm Nucleoplasm "HPA003750: AB_1856383" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (2.82e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-2)" "unprognostic (1.10e-1)" "prognostic unfavourable (1.37e-4)" "unprognostic (4.48e-3)" "unprognostic (1.28e-1)" "unprognostic (4.05e-3)" "unprognostic (3.76e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-3)" "unprognostic (9.83e-2)" "unprognostic (6.55e-2)" "unprognostic (1.67e-1)" "unprognostic (8.08e-3)" 9.1 12.1 10.2 19.6 12.2 14.2 9.9 18.5 13.1 10.0 8.1 8.7 7.0 7.4 11.1 7.2 12.5 8.7 7.2 9.6 10.5 16.0 9.4 11.8 9.4 26.3 9.8 6.4 10.4 6.6 12.1 23.1 11.6 11.1 9.8 9.8 9.4 8.4 11.6 10.5 9.0 10.7 10.7 10.7 14.3 7.5 15.0 10.4 28.0 10.0 7.8 28.2 10.9 13.8 18.6 4.4 5.7 4.6 8.0 8.4 4.3 5.6 8.6 13.5 17.1 7.9 8.4 8.1 12.9 8.5 10.5 13.3 9.8 4.3 14.6 10.6 9.2 7.1 15.7 10.4 19.4 19.8 12.3 19.0 7.8 7.8 6.5 20.3 10.8 5.3 9.2 10.9 10.6 9.3 18.7 11.8 15.6 7.5 8.9 14.5 8.1 7.6 17.7 20.9 8.3 9.4 8.8 7.9 11.4 10.7 6.5 7.0 7.0 20.4 7.3 8.5 7.9 9.6 17.4 10.7 18.7 8.2 12.5 15.2 15.5 3.5 3.0 5.7 6.4 4.6 6.4 18.6 7.2 7.9 4.4 16.8 8.2 8.4 2.5 8.0 3.9 3.1 6.7 4.3 10.2 12.2 18.5 13.1 10.5 16.0 9.8 6.4 11.1 10.4 RNMT RG7MT1 ENSG00000101654 "RNA guanine-7 methyltransferase" O43148 18 13726660-13764558 "Enzymes, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039409 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" Nucleoplasm "Nucleoli fibrillar center" "HPA039409: AB_10795289" "unprognostic (3.02e-1)" "unprognostic (1.07e-2)" "unprognostic (3.48e-1)" "unprognostic (1.71e-3)" "unprognostic (3.57e-1)" "unprognostic (3.04e-1)" "unprognostic (6.17e-3)" "unprognostic (1.43e-1)" "unprognostic (3.76e-2)" "unprognostic (1.42e-3)" "unprognostic (9.45e-2)" "unprognostic (9.15e-2)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (2.77e-2)" "unprognostic (1.78e-1)" 18.9 10.1 13.3 12.7 20.4 40.1 16.6 19.7 27.3 14.0 11.5 10.3 12.1 9.1 15.4 13.1 12.6 12.2 9.9 21.2 14.9 18.2 12.9 12.0 12.4 14.6 14.5 21.8 19.6 13.3 16.6 21.2 16.1 28.5 14.7 11.6 10.8 12.8 12.2 29.1 14.3 11.3 15.1 16.1 12.3 11.4 17.1 12.6 12.2 19.2 15.8 15.8 26.5 11.4 20.1 20.8 21.6 13.1 9.4 15.7 4.1 11.4 6.8 13.2 9.9 9.8 12.5 9.2 9.4 11.7 9.8 13.3 8.0 5.5 12.8 11.6 9.6 4.6 15.5 13.5 16.6 7.1 8.3 9.6 7.0 7.5 10.8 25.0 8.2 9.5 14.7 10.3 29.1 7.5 14.4 12.9 11.1 7.1 15.9 9.0 10.1 5.3 10.4 13.9 17.4 9.0 9.0 10.2 15.3 10.6 7.8 18.1 6.8 10.5 7.7 19.7 27.7 16.0 10.0 26.0 28.3 26.6 14.5 9.6 9.8 21.6 13.1 8.5 12.5 10.3 10.1 16.2 11.9 10.3 8.1 20.1 15.7 12.2 7.1 9.4 11.4 20.8 12.8 4.1 13.3 20.4 19.7 27.3 14.9 18.2 14.5 21.8 28.5 12.6 RNPEP APB ENSG00000176393 "Arginyl aminopeptidase" Q9H4A4 1 201982372-202006147 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 12.1;granulocytes: 12.3;monocytes: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036074, HPA036075, HPA061487" Approved Supported "Nucleoplasm,Golgi apparatus" "Secreted - unknown location" 6600000 "Golgi apparatus" Nucleoplasm "HPA036074: AB_2674926, HPA036075: AB_10672999, HPA061487: " "unprognostic (8.57e-2)" "unprognostic (3.43e-2)" "unprognostic (2.81e-1)" "unprognostic (5.45e-2)" "unprognostic (2.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.95e-2)" "unprognostic (2.87e-2)" "unprognostic (1.93e-3)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (3.50e-3)" "unprognostic (1.91e-1)" "unprognostic (6.00e-2)" "unprognostic (1.97e-2)" "unprognostic (1.68e-1)" 18.5 22.0 6.4 14.9 8.2 9.5 16.7 9.2 11.0 17.8 34.2 13.5 21.2 31.1 17.4 18.7 33.2 19.2 21.8 11.5 6.1 4.6 22.5 18.3 21.5 14.1 7.0 5.4 18.0 19.5 11.6 10.4 26.3 9.0 18.4 26.8 16.4 25.1 13.6 10.0 18.3 66.6 12.8 8.1 22.7 15.7 21.2 6.0 13.9 28.4 19.1 24.7 17.6 17.5 2.3 12.1 12.3 17.0 1.6 3.1 2.2 19.0 20.7 12.3 18.5 20.2 19.0 31.1 14.7 28.5 18.4 20.8 14.8 24.4 4.1 18.9 25.8 34.6 15.7 28.7 12.9 11.3 20.3 10.4 9.9 13.9 17.2 26.4 36.8 17.3 29.7 16.4 18.9 33.1 23.6 6.2 18.6 17.4 3.6 11.2 17.4 10.3 13.9 17.4 29.4 38.3 17.3 14.3 12.1 36.3 45.4 14.6 34.5 15.1 23.6 8.7 11.7 8.4 17.8 13.8 11.1 3.7 8.6 22.5 17.3 10.8 9.2 12.3 1.9 15.7 2.6 1.6 2.0 2.2 12.1 2.3 1.8 2.1 6.7 1.6 17.0 4.5 3.1 2.2 6.4 8.2 9.2 11.0 6.1 4.6 7.0 5.4 9.0 6.0 RNPEPL1 ENSG00000142327 "Arginyl aminopeptidase like 1" Q9HAU8 2 240565804-240581372 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036772 Uncertain Approved Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA036772: AB_10670848" "unprognostic (3.92e-2)" "unprognostic (7.28e-2)" "unprognostic (1.20e-2)" "unprognostic (2.39e-1)" "unprognostic (5.24e-3)" "prognostic favourable (7.43e-4)" "prognostic unfavourable (5.06e-4)" "unprognostic (3.72e-3)" "unprognostic (9.10e-2)" "unprognostic (1.66e-3)" "unprognostic (3.10e-1)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (5.31e-2)" "unprognostic (9.86e-2)" 17.2 13.7 10.1 13.7 8.8 17.2 48.4 7.2 10.5 11.0 21.0 9.5 11.8 18.6 8.0 8.9 22.1 8.0 22.3 28.3 9.2 6.0 18.2 26.7 32.2 54.1 12.9 8.2 7.1 40.0 7.7 4.3 10.1 8.1 14.9 9.1 7.0 21.5 13.5 26.5 22.5 31.0 11.4 9.7 25.7 20.0 5.9 7.6 23.1 8.8 16.7 12.1 14.4 18.8 7.0 7.6 22.4 9.1 7.6 12.4 5.4 6.8 11.5 2.5 6.8 9.4 9.8 8.7 4.4 11.0 5.0 6.2 3.1 20.2 2.0 2.3 11.1 7.5 2.9 8.2 0.5 12.0 4.0 4.5 3.7 18.6 23.7 2.9 8.2 11.6 13.4 2.6 5.1 17.0 3.3 13.4 3.3 9.7 3.7 11.1 3.4 4.6 7.8 3.8 16.6 20.2 9.5 2.4 5.1 3.0 10.3 20.0 7.2 13.6 11.6 5.4 5.6 7.5 5.0 12.7 1.9 2.3 11.1 8.3 8.1 5.8 9.1 22.4 12.4 7.8 10.6 7.0 9.6 11.1 6.4 6.8 5.4 8.1 16.0 7.6 7.6 7.6 11.1 5.4 10.1 8.8 7.2 10.5 9.2 6.0 12.9 8.2 8.1 7.6 ROCK1 p160ROCK ENSG00000067900 "Rho associated coiled-coil containing protein kinase 1" Q13464 18 20946906-21111851 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004562, HPA007567, HPA045639" Approved 240000 "CAB004562: AB_628223, HPA007567: AB_1856393, HPA045639: " "unprognostic (7.86e-2)" "unprognostic (2.86e-2)" "unprognostic (1.22e-1)" "unprognostic (6.63e-2)" "unprognostic (9.90e-2)" "unprognostic (1.17e-1)" "unprognostic (6.74e-2)" "unprognostic (1.00e-1)" "unprognostic (1.63e-1)" "unprognostic (8.89e-3)" "prognostic unfavourable (9.93e-4)" "unprognostic (3.85e-2)" "unprognostic (8.93e-3)" "unprognostic (3.04e-2)" "unprognostic (5.47e-2)" "unprognostic (3.19e-1)" "unprognostic (1.28e-1)" 19.3 9.7 9.7 16.3 9.7 40.0 15.1 18.3 11.0 13.9 12.6 7.1 14.4 10.1 16.0 14.9 13.3 14.4 11.7 11.9 10.3 5.6 10.5 9.2 17.0 20.5 10.1 6.0 13.7 9.5 11.2 12.2 11.5 10.3 14.2 9.4 9.5 9.4 9.8 7.9 8.5 11.6 27.7 10.7 17.3 12.0 6.6 12.4 24.8 10.9 9.6 11.2 17.9 21.0 5.4 5.3 17.9 5.0 2.6 5.1 2.0 6.4 4.0 4.0 3.9 7.6 8.2 6.6 9.0 4.4 4.0 4.4 6.7 2.8 8.0 6.5 10.6 5.3 3.6 5.2 8.1 11.3 4.2 6.4 7.4 2.9 3.9 17.5 10.0 5.9 4.8 6.0 4.9 6.1 3.6 8.3 4.7 4.1 8.2 3.8 3.4 6.8 11.7 4.7 3.1 3.9 6.0 4.7 3.7 7.2 4.9 3.6 4.8 6.7 10.1 8.1 6.7 7.3 7.3 11.4 5.1 9.2 6.1 7.5 5.0 2.8 5.0 6.3 5.1 3.1 4.1 3.7 3.8 3.9 4.0 5.4 3.7 3.6 17.9 2.6 3.6 5.3 3.2 2.0 9.7 9.7 18.3 11.0 10.3 5.6 10.1 6.0 10.3 12.4 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179761-11348330 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol 3700000 Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavourable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 26.9 7.8 14.6 9.5 21.9 4.4 21.4 26.1 26.4 16.6 16.5 5.6 8.6 12.3 22.4 11.0 12.4 13.2 11.9 12.3 13.4 7.6 11.4 12.3 16.7 6.8 7.2 16.7 15.1 8.6 12.9 14.8 18.4 10.3 14.4 20.3 5.6 10.3 14.4 28.0 8.7 13.8 42.9 7.1 12.6 10.7 5.8 9.6 5.9 10.5 5.1 6.2 22.1 20.8 2.5 3.0 3.6 2.2 3.5 3.3 0.9 6.5 15.9 13.2 12.9 23.8 16.7 8.4 15.5 14.5 10.1 10.7 15.0 14.3 8.2 9.2 24.5 7.3 9.5 8.9 16.0 11.7 5.7 16.4 27.4 30.0 8.6 9.1 4.7 13.0 5.7 12.4 8.9 16.1 14.2 3.3 15.0 5.5 6.7 4.7 7.3 9.8 8.1 29.0 2.6 5.5 18.5 6.2 6.6 30.4 10.6 10.6 4.3 5.1 21.9 20.9 15.1 8.3 13.6 2.6 3.2 7.3 9.0 10.8 29.1 3.6 1.8 1.7 2.7 2.2 3.3 1.6 2.2 1.8 1.3 2.5 1.9 2.1 3.0 3.5 1.7 3.0 1.8 0.9 14.6 21.9 26.1 26.4 13.4 7.6 7.2 16.7 10.3 9.6 ROR1 NTRKR1 ENSG00000185483 "Receptor tyrosine kinase like orphan receptor 1" Q01973 1 63774022-64181498 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 31.2" "Cell line enhanced" "Detected in many" "ASC diff: 19.4;ASC TERT1: 24.3;CACO-2: 16.6;HHSteC: 18.5;HSkMC: 19.9;NTERA-2: 20.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "cerebellum: 13.0" "Group enriched" "Detected in some" 5 "NK-cell: 3.3;plasmacytoid DC: 1.1" "Group enriched" "Detected in many" 5 "dendritic cells: 1.1;NK-cells: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA057016 Approved Microtubules "Intracellular and membrane" 2800000 Microtubules "HPA057016: " "unprognostic (5.15e-2)" "unprognostic (1.19e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-2)" "unprognostic (6.24e-2)" "unprognostic (1.61e-1)" "unprognostic (7.11e-3)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "unprognostic (3.84e-1)" "unprognostic (3.20e-2)" "unprognostic (2.02e-2)" "unprognostic (3.64e-3)" "unprognostic (1.48e-2)" "unprognostic (1.52e-1)" "unprognostic (5.87e-2)" "unprognostic (5.15e-2)" 5.5 1.7 1.3 3.5 2.7 0.4 3.4 13.0 2.8 16.7 8.8 2.2 4.4 2.0 14.2 5.0 4.9 5.5 10.7 10.6 1.3 1.1 3.6 0.8 9.7 1.1 1.0 2.4 8.3 9.8 31.2 3.6 2.9 3.0 10.9 3.9 7.9 2.8 6.3 2.1 4.5 4.1 17.8 1.1 3.1 9.2 2.7 0.9 1.8 1.5 4.6 2.1 10.2 8.8 0.4 1.1 0.1 0.1 3.3 0.1 0.0 7.0 5.5 2.8 0.3 19.4 24.3 1.9 1.3 3.8 0.7 2.0 16.6 2.2 0.1 3.2 3.2 1.5 0.0 1.3 0.5 0.0 1.7 0.0 0.7 0.2 18.5 0.0 0.0 19.9 5.1 10.2 12.0 0.3 0.0 0.1 5.1 0.1 0.1 0.0 20.2 2.8 0.1 0.1 4.3 4.1 0.1 1.6 6.5 0.4 0.1 2.9 0.0 0.0 3.8 1.5 2.9 10.8 2.8 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.1 3.3 0.1 1.1 0.0 0.0 1.3 2.7 13.0 2.8 1.3 1.1 1.0 2.4 3.0 0.9 ROR2 "BDB, BDB1, NTRKR2" ENSG00000169071 "Receptor tyrosine kinase like orphan receptor 2" Q01974 9 91563091-91950162 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 12.0;HHSteC: 31.7;HSkMC: 26.4;U-266/70: 18.3;U-266/84: 12.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 6 "pons and medulla: 6.6" "Cell type enriched" "Detected in single" 6 "MAIT T-cell: 3.9" "Lineage enriched" "Detected in single" 6 "T-cells: 3.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "cerebellum: 13.5" HPA021868 Uncertain "HPA021868: AB_1856406" "unprognostic (9.38e-3)" "unprognostic (4.69e-1)" "unprognostic (2.26e-1)" "unprognostic (8.48e-3)" "unprognostic (1.23e-1)" "unprognostic (2.38e-1)" "unprognostic (2.06e-1)" "unprognostic (1.31e-1)" "unprognostic (8.03e-2)" "unprognostic (2.03e-1)" "unprognostic (5.76e-2)" "unprognostic (2.66e-1)" "prognostic unfavourable (9.86e-7)" "unprognostic (2.16e-3)" "unprognostic (9.13e-2)" "prognostic unfavourable (4.28e-8)" "unprognostic (1.25e-2)" 4.4 4.3 0.7 5.3 1.1 0.0 3.6 0.2 0.8 23.4 20.7 2.9 11.1 1.9 29.1 9.1 8.0 8.1 18.7 8.5 1.0 0.9 2.0 0.5 4.2 0.7 0.3 0.0 19.1 3.1 20.3 1.3 7.1 6.6 20.3 2.1 11.0 1.2 13.1 1.1 2.9 6.2 30.0 0.3 4.7 10.5 5.2 0.3 2.6 7.9 1.9 3.3 23.7 18.1 0.6 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.1 12.0 0.0 2.6 0.2 3.4 0.2 3.1 2.0 3.8 0.0 0.0 0.0 0.0 0.6 0.1 2.5 0.0 0.8 0.0 2.0 0.0 9.2 0.0 31.7 0.0 0.0 26.4 0.0 2.7 0.0 0.0 6.6 0.0 0.0 0.2 0.0 1.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.5 0.2 0.0 0.0 7.1 0.1 0.0 0.0 2.4 1.0 0.0 18.3 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.2 0.8 1.0 0.9 0.3 0.0 6.6 0.3 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117288300-117425855 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 38.6;lung: 20.2" "Group enriched" "Detected in some" 5 "HSkMC: 9.3;hTCEpi: 19.3;LHCN-M2: 13.4" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Group enriched" "Detected in some" 10 "cerebral cortex: 7.4;olfactory region: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles Vesicles "HPA049098: , HPA072424: " "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.3 0.2 0.2 0.0 0.4 0.0 0.2 0.2 7.4 0.2 0.4 0.0 7.9 0.0 0.2 38.6 0.2 0.2 0.0 0.2 0.2 0.2 0.4 0.2 20.2 0.0 0.2 2.5 0.2 0.2 0.0 0.3 0.7 0.0 0.2 0.3 0.0 0.2 2.3 0.2 0.7 0.3 0.0 0.2 0.2 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 9.3 19.3 0.2 1.7 0.0 0.0 0.0 13.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.8 0.0 2.3 1.5 0.1 1.8 0.0 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.2 7.4 0.2 0.2 0.2 2.5 0.0 0.0 RPAP2 "C1orf82, FLJ13150, Rtr1" ENSG00000122484 "RNA polymerase II associated protein 2" Q8IXW5 1 92298965-92402056 "Enzymes, Predicted membrane proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046443 Approved Supported Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA046443: " "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.71e-2)" "unprognostic (4.12e-2)" "unprognostic (4.96e-3)" "unprognostic (5.73e-2)" "unprognostic (1.23e-3)" "unprognostic (3.29e-2)" "unprognostic (8.01e-3)" "unprognostic (4.09e-2)" "unprognostic (2.59e-1)" "unprognostic (6.09e-2)" "unprognostic (7.02e-4)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.62e-3)" "unprognostic (4.10e-2)" 6.8 7.0 7.8 7.3 10.5 12.0 7.6 27.2 11.6 8.4 6.3 7.1 7.2 6.6 11.1 11.5 5.6 6.3 5.5 5.9 8.1 8.6 8.1 10.6 5.2 8.2 7.7 6.7 8.2 8.6 9.4 16.1 6.7 11.7 7.6 5.8 6.4 7.2 7.1 10.5 10.7 6.3 7.4 9.9 7.6 6.4 6.7 8.7 12.8 9.4 6.5 6.3 6.6 7.6 4.4 3.5 4.9 2.4 4.0 4.8 1.2 6.2 3.8 6.7 6.1 5.5 7.1 5.7 4.9 3.4 3.2 2.7 2.7 2.8 9.3 8.5 3.6 4.3 5.5 3.2 5.0 6.3 4.0 5.7 6.9 3.6 3.3 9.8 5.7 3.6 3.9 4.2 4.1 3.4 5.8 6.2 4.9 3.2 8.3 6.2 5.2 4.3 6.2 8.9 4.0 4.2 5.6 6.2 4.6 8.0 7.3 4.0 3.9 7.5 6.0 4.9 6.2 5.6 6.9 6.0 7.0 4.9 3.4 6.2 3.3 4.8 2.4 1.9 4.1 1.7 4.8 3.4 3.2 3.5 1.8 4.4 3.5 3.8 4.9 4.0 1.9 3.5 2.8 1.2 7.8 10.5 27.2 11.6 8.1 8.6 7.7 6.7 11.7 8.7 RPE ENSG00000197713 Ribulose-5-phosphate-3-epimerase Q96AT9 2 210002565-210022259 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: , HPA036499: AB_10670109" "unprognostic (5.07e-2)" "unprognostic (8.15e-2)" "unprognostic (3.06e-1)" "unprognostic (2.34e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-2)" "prognostic unfavourable (1.42e-6)" "unprognostic (1.59e-3)" "unprognostic (1.69e-2)" "unprognostic (1.28e-1)" "prognostic unfavourable (7.00e-6)" "unprognostic (2.33e-2)" "unprognostic (2.55e-2)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "unprognostic (5.84e-2)" 19.4 26.9 20.6 16.7 28.0 14.6 22.6 26.4 27.7 18.7 19.7 23.3 20.7 17.4 27.8 21.5 24.0 17.6 17.3 17.2 21.1 21.0 26.7 23.3 19.4 21.6 21.7 21.7 22.9 14.1 14.8 41.9 24.4 18.6 20.5 26.6 18.9 18.3 27.9 12.3 17.2 16.0 27.1 25.8 15.6 19.8 11.9 19.7 23.5 25.2 14.5 23.2 24.1 20.2 8.6 28.9 8.0 20.5 30.5 10.7 11.3 21.0 27.2 17.7 17.8 28.8 27.9 30.4 27.7 22.2 26.3 35.4 39.2 32.2 14.2 18.2 21.4 20.7 26.0 29.5 40.3 17.0 18.4 26.2 40.0 36.5 39.3 27.8 20.2 19.5 29.4 30.2 39.4 34.2 26.4 19.8 21.6 33.5 15.1 24.2 26.0 20.0 19.0 21.1 20.3 30.4 31.4 21.3 12.2 23.4 22.9 18.5 19.7 32.0 28.0 35.4 23.5 17.2 25.5 11.8 15.0 30.4 25.6 27.5 22.8 6.9 17.3 8.0 10.2 20.5 8.9 8.6 8.0 9.6 28.9 8.4 10.7 9.6 1.7 30.5 13.7 10.6 10.7 11.3 20.6 28.0 26.4 27.7 21.1 21.0 21.7 21.7 18.6 19.7 RPEL1 ENSG00000235376 "Ribulose-5-phosphate-3-epimerase like 1" Q2QD12 10 103245887-103248016 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 1.4;brain: 1.2;pituitary gland: 1.2" "Cell line enhanced" "Detected in some" "HeLa: 1.1;NB-4: 1.0" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: , HPA036499: AB_10670109" "unprognostic (7.52e-2)" "unprognostic (1.69e-1)" "unprognostic (4.78e-2)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (1.83e-1)" "unprognostic (6.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.91e-2)" "unprognostic (6.59e-2)" "unprognostic (4.34e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (1.62e-1)" "unprognostic (6.72e-2)" "unprognostic (5.06e-2)" 0.0 0.1 0.1 1.0 0.3 0.1 0.1 1.2 0.2 0.0 0.0 0.3 0.4 0.4 0.1 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.4 0.1 0.0 0.8 0.0 1.2 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.4 1.0 0.3 0.7 1.4 0.6 0.2 0.5 0.5 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.2 0.4 0.7 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.3 1.1 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 1.0 0.7 0.0 0.0 0.1 0.3 0.5 0.2 0.3 0.1 0.3 0.4 0.2 0.1 0.4 0.0 0.1 0.9 0.1 0.2 0.3 0.1 0.3 0.7 0.4 0.1 0.3 0.7 0.2 0.5 0.7 0.5 0.4 0.4 0.3 1.0 0.4 0.5 0.6 0.0 1.4 0.4 0.3 0.4 0.2 RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691644-88750935 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" 4100000 "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: AB_10793980, HPA057954: " "unprognostic (3.35e-2)" "unprognostic (1.35e-2)" "unprognostic (6.96e-2)" "unprognostic (9.24e-2)" "unprognostic (4.31e-1)" "unprognostic (8.24e-2)" "prognostic unfavourable (1.46e-5)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (8.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.79e-1)" "prognostic unfavourable (8.53e-6)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (8.79e-3)" 12.9 8.8 6.6 15.6 7.0 43.0 12.1 11.1 6.4 8.1 12.7 6.1 11.0 12.4 11.1 7.3 18.3 8.5 14.0 10.9 5.0 4.9 6.8 6.2 9.0 16.2 7.2 3.8 11.7 26.5 3.6 11.4 26.1 6.5 8.8 13.4 6.0 12.6 8.5 17.6 9.2 12.7 7.7 5.1 15.4 10.4 8.9 7.6 30.7 9.6 10.5 19.3 8.1 11.8 18.5 14.1 21.4 12.5 13.3 22.4 11.6 8.5 5.0 10.2 8.0 7.2 7.4 22.3 4.8 4.5 7.9 5.4 17.8 11.4 43.7 10.4 5.5 5.2 12.6 4.0 12.5 20.7 16.5 17.5 3.2 17.5 7.3 32.0 12.9 6.8 3.4 7.0 11.0 11.1 18.7 7.6 7.4 13.4 35.1 28.0 9.2 8.2 18.4 12.1 10.6 6.5 13.8 7.3 8.3 5.7 7.4 11.0 4.0 13.2 6.3 4.7 12.4 15.4 13.6 5.9 4.8 43.7 4.8 29.1 6.7 5.5 9.7 21.4 11.1 9.8 14.2 18.5 15.5 16.4 14.1 15.4 22.4 18.4 2.3 13.3 12.5 6.8 12.6 11.6 6.6 7.0 11.1 6.4 5.0 4.9 7.2 3.8 6.5 7.6 RPP14 P14 ENSG00000163684 "Ribonuclease P/MRP subunit p14" O95059 3 58306247-58324695 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 53.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036194 Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA036194: AB_10672082" "unprognostic (6.05e-2)" "unprognostic (2.02e-2)" "unprognostic (1.50e-3)" "unprognostic (1.36e-1)" "unprognostic (4.08e-3)" "unprognostic (2.51e-1)" "unprognostic (1.30e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (2.95e-3)" "unprognostic (3.76e-2)" "prognostic favourable (3.07e-10)" "unprognostic (5.19e-3)" "unprognostic (2.36e-1)" "prognostic unfavourable (2.96e-4)" "unprognostic (5.78e-2)" 7.1 8.5 8.3 5.7 12.9 5.3 7.1 15.8 10.7 6.6 8.6 5.9 6.6 10.2 8.2 7.8 8.5 7.4 6.2 11.8 7.2 6.8 11.2 15.0 5.6 7.6 6.5 9.9 8.4 11.9 10.8 9.4 6.0 7.2 7.4 8.2 9.0 8.5 7.0 53.5 7.4 9.1 11.7 5.5 7.7 7.7 9.1 5.9 6.3 8.1 18.5 8.5 7.2 7.0 4.6 6.6 4.7 9.8 9.8 6.4 3.5 10.1 8.0 9.4 7.4 7.8 8.4 10.3 8.6 9.2 12.3 13.9 12.2 6.7 12.1 2.0 11.5 6.2 14.0 12.7 12.0 8.4 7.4 11.5 9.6 6.6 7.7 19.8 9.6 9.2 12.3 14.6 14.0 9.7 9.9 8.7 11.9 5.5 13.4 7.0 12.3 15.3 5.5 7.4 11.7 9.0 14.5 5.9 10.4 8.0 9.6 11.5 9.2 9.6 8.8 9.3 10.4 9.8 16.2 13.0 22.2 17.5 10.7 13.9 6.6 3.0 5.7 4.7 4.2 4.9 5.6 4.1 5.5 5.8 6.6 4.6 6.4 6.2 2.6 9.8 9.8 6.2 3.0 3.5 8.3 12.9 15.8 10.7 7.2 6.8 6.5 9.9 7.2 5.9 RPP25 FLJ20374 ENSG00000178718 "Ribonuclease P and MRP subunit p25" Q9BUL9 15 74954416-74957464 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 18.6;SCLC-21H: 17.1;SK-MEL-30: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 16.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.7;monocytes: 6.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046900 Approved Supported "Nucleoplasm,Centriolar satellite" Nucleoplasm "Centriolar satellite" "HPA046900: AB_10962049" "unprognostic (9.36e-2)" "unprognostic (7.17e-3)" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "prognostic unfavourable (2.24e-5)" "unprognostic (7.18e-2)" "unprognostic (5.73e-3)" "unprognostic (5.50e-3)" "unprognostic (7.78e-2)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (4.71e-3)" "unprognostic (5.50e-3)" "unprognostic (5.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-1)" 3.9 7.3 3.0 1.9 4.6 0.0 2.2 3.2 14.0 3.4 6.7 3.7 1.2 6.0 1.7 1.3 3.3 1.8 3.7 2.5 2.5 6.8 2.6 1.9 5.1 2.7 8.0 5.1 12.0 4.9 9.0 2.8 6.1 10.6 2.1 4.1 3.2 2.4 1.3 1.9 2.1 4.6 2.0 7.9 6.2 5.6 1.9 1.8 3.1 4.9 2.6 2.5 4.1 2.4 2.3 16.7 0.3 6.4 0.3 2.7 1.4 8.9 6.8 1.7 0.0 0.6 0.4 2.9 1.7 2.0 0.5 0.4 9.2 8.2 0.0 7.8 1.7 2.7 5.3 0.3 0.1 3.3 0.2 0.0 7.9 0.2 18.6 0.0 5.3 2.4 0.2 3.4 0.0 7.9 6.0 0.0 1.7 3.4 1.4 2.3 8.2 2.7 0.0 0.0 6.0 1.6 0.1 17.1 12.8 12.8 11.3 25.5 2.2 7.1 1.8 0.0 0.7 1.6 0.0 0.1 0.0 0.0 0.9 13.9 10.0 0.0 3.3 0.0 1.5 6.4 0.9 2.3 1.1 1.3 3.3 1.9 2.7 2.1 0.3 0.3 4.8 16.7 0.4 1.4 3.0 4.6 3.2 14.0 2.5 6.8 8.0 5.1 10.6 1.8 RPP30 TSG15 ENSG00000148688 "Ribonuclease P/MRP subunit p30" P78346 10 90871716-90908553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037578 Approved Approved "Nucleoplasm,Nucleoli,Microtubule ends,Cytosol" "Nucleoplasm, Nucleoli" "Microtubule ends, Cytosol" "HPA037578: AB_10696939" "unprognostic (1.55e-1)" "unprognostic (1.77e-3)" "unprognostic (2.35e-1)" "unprognostic (4.08e-1)" "unprognostic (5.64e-2)" "unprognostic (3.05e-2)" "unprognostic (3.80e-3)" "unprognostic (1.27e-1)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (2.27e-2)" "unprognostic (2.65e-1)" "prognostic unfavourable (1.01e-6)" "unprognostic (1.98e-1)" "unprognostic (9.84e-3)" "unprognostic (3.43e-2)" "unprognostic (2.10e-2)" 24.2 19.0 20.9 16.8 20.3 27.2 22.3 26.0 24.0 18.9 19.0 16.2 16.3 11.5 25.2 18.6 23.8 19.2 16.0 26.6 19.8 16.8 20.6 18.4 17.1 23.2 18.5 20.4 23.9 17.7 37.7 23.6 23.6 19.3 18.8 19.3 18.7 19.2 16.5 35.9 23.5 16.4 20.6 19.2 21.3 19.2 32.0 21.6 31.2 18.1 24.0 26.3 21.7 18.9 19.4 22.2 16.2 19.5 14.2 20.3 16.2 28.0 18.7 19.6 23.6 12.8 13.8 6.9 20.1 18.1 33.7 35.4 31.6 22.6 16.6 15.4 12.8 19.7 26.1 17.8 34.7 26.6 18.0 11.1 12.0 24.9 12.1 22.5 14.1 11.3 11.6 25.3 28.8 19.1 22.1 15.2 22.2 17.3 26.1 30.7 12.1 21.3 14.6 16.7 17.4 12.7 13.3 10.6 10.7 11.7 8.5 23.6 23.0 14.3 10.8 16.8 16.8 9.5 41.4 10.3 26.3 35.6 21.1 12.2 12.9 4.3 19.5 16.2 17.1 18.7 18.6 19.4 19.6 18.7 22.2 16.7 17.0 18.5 2.2 14.2 15.3 20.7 20.3 16.2 20.9 20.3 26.0 24.0 19.8 16.8 18.5 20.4 19.3 21.6 RPP38 ENSG00000152464 "Ribonuclease P/MRP subunit p38" P78345 10 15097180-15139818 "Enzymes, Predicted intracellular proteins, Ribosomal proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045128, HPA050398" Approved Supported Nucleoli Nucleoli "HPA045128: , HPA050398: " "unprognostic (1.75e-1)" "unprognostic (3.91e-2)" "unprognostic (3.76e-2)" "unprognostic (1.51e-1)" "unprognostic (9.93e-2)" "unprognostic (1.17e-1)" "prognostic unfavourable (1.46e-4)" "unprognostic (1.41e-2)" "unprognostic (4.86e-1)" "unprognostic (1.57e-3)" "unprognostic (3.42e-1)" "unprognostic (7.21e-2)" "prognostic unfavourable (6.25e-4)" "unprognostic (6.13e-2)" "unprognostic (1.95e-1)" "unprognostic (5.11e-2)" "prognostic favourable (2.89e-6)" 13.1 12.2 12.4 10.7 13.6 9.7 18.3 22.4 12.4 13.6 16.7 12.0 15.8 14.4 15.7 16.1 15.2 18.2 10.3 10.0 11.6 10.2 17.4 21.6 12.5 16.3 15.0 10.0 14.4 16.8 11.3 16.0 17.4 12.7 18.4 15.7 11.7 17.1 14.9 20.9 14.8 17.9 14.3 11.5 16.7 13.5 38.6 12.7 18.8 19.8 13.9 18.5 13.4 13.6 31.0 25.7 23.4 24.5 18.6 31.4 20.2 20.9 15.9 8.7 11.2 11.8 12.2 15.4 10.2 7.7 16.0 16.5 16.0 22.1 17.6 11.0 9.5 19.7 17.5 17.7 14.8 13.4 15.9 18.1 9.7 14.0 25.4 10.2 15.3 14.5 24.5 13.1 11.6 12.8 20.9 12.6 12.2 17.3 18.2 11.2 10.1 7.8 15.0 8.8 21.9 20.5 8.3 8.3 10.5 14.1 24.5 28.2 21.9 16.5 11.0 7.4 12.9 15.6 13.4 17.5 18.7 24.0 14.5 12.5 7.0 8.5 24.5 23.4 25.6 23.7 25.1 28.8 26.2 31.4 25.3 31.0 30.6 27.8 8.3 18.6 18.6 25.7 22.0 20.2 12.4 13.6 22.4 12.4 11.6 10.2 15.0 10.0 12.7 12.7 RPP40 "bA428J1.3, RNASEP1" ENSG00000124787 "Ribonuclease P/MRP subunit p40" O75818 6 4994732-5004063 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035685, HPA035686" Uncertain Approved Nucleoplasm Nucleoplasm "HPA035685: , HPA035686: AB_10670153" "unprognostic (2.93e-2)" "unprognostic (3.22e-2)" "unprognostic (1.94e-1)" "prognostic unfavourable (6.10e-6)" "unprognostic (8.00e-2)" "unprognostic (4.78e-2)" "prognostic unfavourable (5.41e-4)" "unprognostic (1.20e-1)" "unprognostic (1.72e-2)" "unprognostic (6.44e-2)" "unprognostic (8.17e-2)" "unprognostic (9.57e-2)" "prognostic unfavourable (7.54e-8)" "unprognostic (1.54e-1)" "unprognostic (5.10e-1)" "unprognostic (4.08e-2)" "unprognostic (2.19e-1)" 6.9 16.8 10.8 7.2 10.7 6.7 11.1 3.5 11.9 6.0 5.5 4.2 6.3 4.6 6.1 6.6 11.9 5.5 4.7 5.5 10.0 8.8 5.6 10.8 3.9 10.1 9.9 5.8 6.2 7.8 5.2 8.6 5.6 9.1 5.3 5.3 1.5 4.0 6.7 7.7 9.8 3.6 7.5 5.3 6.8 4.3 10.5 8.0 6.1 5.6 13.0 8.3 9.1 6.9 7.8 12.3 0.0 11.1 7.9 8.4 5.0 6.4 10.7 3.4 9.6 6.3 8.1 10.8 6.3 3.2 12.1 9.7 14.5 4.9 13.9 28.1 6.6 6.8 7.0 9.8 11.1 5.2 14.0 8.7 7.0 19.7 7.4 11.2 5.0 6.3 8.4 12.1 12.1 11.9 13.7 2.8 8.8 18.2 5.6 19.3 5.6 17.5 12.1 6.4 25.4 6.2 7.0 12.2 3.5 5.9 5.7 6.3 10.4 9.3 5.6 16.1 10.8 10.8 14.4 5.0 20.9 10.9 3.0 18.8 8.2 0.0 6.9 0.0 3.4 11.1 5.0 7.8 5.9 4.1 12.3 6.5 8.1 7.2 0.0 7.9 3.5 5.9 8.4 5.0 10.8 10.7 3.5 11.9 10.0 8.8 9.9 5.8 9.1 8.0 RPS3 "FLJ26283, FLJ27450, MGC87870, S3" ENSG00000149273 "Ribosomal protein S3" P23396 11 75399486-75422280 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Lyase, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063339 Uncertain Supported "Endoplasmic reticulum,Cytosol" 430000 "Endoplasmic reticulum, Cytosol" "HPA063339: " "unprognostic (3.62e-2)" "unprognostic (6.94e-3)" "unprognostic (2.64e-1)" "unprognostic (1.44e-2)" "unprognostic (5.55e-2)" "unprognostic (1.08e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-1)" "unprognostic (2.69e-1)" "unprognostic (5.75e-2)" "unprognostic (3.27e-3)" "unprognostic (1.96e-1)" "prognostic unfavourable (6.92e-6)" "unprognostic (3.22e-1)" "unprognostic (2.94e-1)" "unprognostic (1.89e-2)" "unprognostic (2.19e-1)" 72.2 52.7 36.6 108.4 41.2 122.2 136.6 32.1 33.8 105.1 102.0 32.5 65.2 65.8 102.4 84.7 136.5 92.2 107.7 58.5 29.7 26.5 52.9 78.1 71.0 218.6 47.6 30.6 224.7 288.7 13.8 51.3 75.9 35.0 105.7 65.7 47.6 151.0 61.8 86.9 117.6 78.0 110.6 42.1 121.4 75.4 54.1 36.5 126.5 119.4 134.7 130.1 110.3 118.9 104.5 69.7 22.6 44.5 64.6 144.2 213.9 85.5 53.1 75.5 83.1 95.5 170.4 97.7 82.1 105.8 109.0 71.1 153.1 102.5 299.4 100.6 73.7 124.1 97.4 152.7 100.5 79.2 76.1 122.6 53.0 67.6 142.6 197.9 80.4 199.9 208.7 74.5 207.1 142.9 122.1 85.3 97.9 94.0 118.7 95.2 94.8 63.0 112.8 264.9 218.1 107.0 71.6 65.0 92.2 60.5 143.9 83.5 146.9 151.7 114.4 52.7 87.8 71.8 74.1 78.3 96.5 331.7 31.6 111.1 53.2 22.6 44.5 14.7 94.2 31.6 129.1 104.5 123.0 99.4 69.7 95.6 144.2 111.8 11.2 64.6 30.1 60.8 78.2 213.9 36.6 41.2 32.1 33.8 29.7 26.5 47.6 30.6 35.0 36.5 RPS6KA1 "HU-1, p90Rsk, RSK, RSK1" ENSG00000117676 "Ribosomal protein S6 kinase A1" Q15418 1 26529761-26575030 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 45.2" "Cell line enhanced" "Detected in many" "HMC-1: 29.6;U-937: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 60.4" "Low region specificity" "Detected in all" "CAB003852, HPA007981" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB003852: AB_289590, HPA007981: AB_1079850" "unprognostic (1.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.61e-3)" "prognostic favourable (7.20e-7)" "unprognostic (7.35e-2)" "unprognostic (3.69e-1)" "unprognostic (6.93e-3)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (7.51e-3)" "unprognostic (2.37e-2)" "unprognostic (9.64e-2)" "prognostic favourable (1.84e-4)" "prognostic favourable (4.58e-4)" "unprognostic (4.77e-2)" "unprognostic (7.61e-2)" "prognostic favourable (8.33e-4)" 11.0 8.2 6.3 24.2 9.7 15.8 5.0 14.4 6.3 4.9 23.2 11.1 4.4 24.5 2.1 3.6 8.9 6.0 8.0 3.4 5.3 5.1 13.6 5.4 26.1 32.7 10.3 3.5 2.1 10.1 10.0 7.4 3.3 8.6 8.6 15.8 3.6 19.0 5.5 1.1 9.0 45.2 2.8 7.9 27.0 9.7 2.7 9.0 15.9 13.9 4.9 17.3 6.2 4.5 5.0 22.0 40.1 18.0 7.9 8.3 17.1 9.7 3.4 2.8 3.7 0.1 0.0 3.7 0.8 1.5 4.2 4.0 4.0 8.1 18.3 4.5 0.5 11.5 6.3 22.7 3.0 15.1 4.1 20.1 8.5 7.0 1.3 23.7 29.6 0.7 8.3 3.8 6.9 1.8 3.4 6.7 0.2 5.4 0.8 23.3 7.2 11.0 12.6 3.6 8.0 12.0 2.7 4.1 1.6 6.9 6.6 3.2 4.2 20.3 1.2 0.2 5.3 0.7 3.3 4.1 4.9 10.0 2.5 31.8 4.0 9.6 18.0 40.1 8.3 16.4 6.9 4.9 6.1 7.3 22.0 5.0 3.9 5.5 34.5 7.9 17.3 8.6 6.0 17.1 6.3 9.7 14.4 6.3 5.3 5.1 10.3 3.5 8.6 9.0 RPS6KA2 "HU-2, RSK, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 53.2;ASC TERT1: 39.0;HHSteC: 39.5;HSkMC: 35.1;hTERT-HME1: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "eosinophil: 17.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: , HPA054237: " "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavourable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favourable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 15.4 6.5 26.8 5.3 35.5 6.9 12.7 12.1 21.5 13.5 7.1 20.3 11.5 4.3 18.3 5.2 14.0 11.9 12.5 40.9 25.0 18.3 9.9 3.3 24.6 10.6 22.4 18.4 20.9 30.2 32.6 18.0 12.1 22.7 10.6 7.4 11.1 9.0 10.5 14.4 7.5 7.2 15.8 37.2 16.5 10.4 5.1 25.7 0.8 24.8 3.5 4.9 15.5 10.2 0.4 3.9 17.5 1.6 3.3 0.6 0.2 2.1 0.0 4.3 6.2 53.2 39.0 0.0 4.6 8.9 2.5 3.6 0.0 1.3 0.2 1.5 16.1 1.9 2.2 9.9 2.3 0.9 0.5 0.0 9.4 0.1 39.5 0.1 1.7 35.1 7.1 13.7 42.4 13.9 0.0 0.0 10.4 0.4 0.2 0.4 1.1 2.5 0.7 2.2 6.2 2.7 2.3 2.4 16.8 1.6 4.3 5.8 0.1 3.3 5.1 9.1 0.9 25.1 1.3 1.2 1.8 0.6 6.0 0.2 8.6 0.1 0.5 17.5 0.5 0.7 0.2 0.3 0.5 0.2 0.7 0.4 0.6 0.3 0.4 3.3 1.6 3.9 0.4 0.2 26.8 35.5 12.1 21.5 25.0 18.3 22.4 18.4 22.7 25.7 RPS6KA3 "CLS, HU-3, MRX19, RSK, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Approved Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "CAB003853: AB_562343, CAB013520: AB_2533378, HPA003221: AB_1853553" "unprognostic (1.87e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (4.26e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (5.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" 19.7 12.5 9.9 23.0 12.5 8.2 16.5 15.2 12.1 11.4 23.2 4.4 22.1 13.7 12.4 10.1 13.6 12.7 15.7 21.3 9.7 8.8 14.1 25.8 21.6 34.0 9.9 10.0 12.7 14.0 36.6 9.8 11.0 10.2 14.5 18.8 7.7 14.3 11.3 45.2 11.7 23.7 16.1 11.7 25.8 11.8 4.8 9.7 29.4 13.5 15.0 18.2 20.3 19.0 4.2 8.6 12.5 6.9 8.3 11.3 2.7 12.6 22.2 8.4 4.3 8.2 14.5 2.5 11.0 16.8 8.2 11.3 25.1 16.4 8.3 3.8 11.5 9.0 9.6 9.3 15.3 7.0 7.6 9.8 14.0 67.5 8.4 19.0 10.2 9.2 7.5 12.9 16.3 29.8 6.4 23.9 8.6 6.0 12.3 5.8 6.0 13.4 6.6 17.8 9.6 7.1 10.6 3.9 3.8 14.8 4.5 16.0 0.0 5.7 16.6 9.0 6.3 28.5 6.2 19.1 11.6 9.3 17.0 9.5 21.2 12.5 4.7 9.5 6.3 6.9 11.3 2.9 7.3 6.9 7.0 4.2 5.0 6.0 7.5 8.3 6.9 8.6 3.5 2.7 9.9 12.5 15.2 12.1 9.7 8.8 9.9 10.0 10.2 9.7 RPS6KA4 "MSK2, RSK-B" ENSG00000162302 "Ribosomal protein S6 kinase A4" O75676 11 64359148-64372215 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 12.6" "Lineage enriched" "Detected in many" 4 "dendritic cells: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008649, HPA023225" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB008649: AB_1619460, HPA023225: AB_1854144" "unprognostic (2.30e-1)" "unprognostic (7.05e-2)" "unprognostic (2.03e-1)" "unprognostic (4.07e-2)" "unprognostic (2.40e-1)" "unprognostic (7.47e-2)" "prognostic unfavourable (8.17e-4)" "prognostic unfavourable (9.27e-4)" "unprognostic (2.45e-1)" "unprognostic (9.03e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-3)" "unprognostic (1.98e-2)" "unprognostic (3.93e-3)" "unprognostic (5.25e-2)" "unprognostic (1.09e-1)" "unprognostic (2.85e-1)" 14.9 9.1 13.3 15.7 17.1 13.2 7.6 37.6 22.7 7.7 12.4 13.1 5.8 14.0 11.0 6.9 18.5 8.1 10.5 7.8 10.9 10.1 8.7 9.6 10.9 15.0 16.7 9.9 6.5 9.2 5.7 4.7 16.6 9.8 8.3 8.4 10.0 10.9 8.9 16.3 17.3 15.4 9.8 11.5 22.2 18.3 3.3 13.5 7.6 6.7 16.7 16.4 9.7 8.8 0.5 12.6 1.4 3.0 0.3 1.0 2.1 27.7 15.5 2.2 5.7 5.0 4.7 32.1 14.7 7.8 11.6 5.8 15.4 14.6 2.8 17.3 8.5 25.7 2.7 12.0 5.7 8.7 5.2 6.5 13.3 7.8 5.0 6.6 12.2 4.7 11.3 9.8 8.1 7.0 2.6 4.0 5.9 25.4 5.9 10.3 2.5 32.9 11.7 9.3 9.3 8.0 12.9 3.3 2.6 15.3 9.4 12.9 11.0 8.2 13.9 15.8 19.9 28.6 13.2 4.8 3.7 2.9 10.5 7.6 8.0 1.1 3.0 1.4 0.9 2.4 1.0 0.5 0.7 0.7 2.7 0.4 0.4 0.4 0.2 0.3 1.4 12.6 0.6 2.1 13.3 17.1 37.6 22.7 10.9 10.1 16.7 9.9 9.8 13.5 RPS6KA5 "MSK1, RLPK" ENSG00000100784 "Ribosomal protein S6 kinase A5" O75582 14 90847862-91060636 "Enzymes, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.5;SK-BR-3: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001274, HPA001780, CAB025458" Approved Enhanced Nucleoplasm Nucleoplasm "CAB025458: , HPA001274: AB_1079417, HPA001780: " "unprognostic (3.05e-2)" "unprognostic (2.19e-3)" "unprognostic (4.27e-4)" "unprognostic (1.98e-3)" "unprognostic (4.79e-2)" "unprognostic (4.20e-4)" "unprognostic (3.70e-2)" "unprognostic (5.80e-4)" "unprognostic (6.70e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "unprognostic (1.38e-4)" "unprognostic (5.73e-3)" "unprognostic (1.07e-1)" "unprognostic (2.42e-1)" "unprognostic (1.75e-1)" 4.9 2.4 8.3 13.0 21.6 5.8 16.3 32.9 12.2 7.0 11.0 12.0 4.2 9.3 11.8 2.6 11.9 8.9 6.7 6.1 9.0 7.9 4.5 4.1 6.1 7.3 12.8 9.7 10.2 4.9 12.0 6.9 14.9 11.0 8.0 11.7 2.8 8.7 9.9 14.3 6.6 9.8 19.4 17.1 7.4 9.8 5.2 13.7 4.8 8.6 7.8 7.7 11.6 7.3 5.8 2.5 20.0 3.2 8.4 7.1 2.2 1.2 1.7 2.0 1.3 0.0 0.4 8.5 0.7 1.1 2.2 3.4 0.9 2.2 5.8 2.4 2.1 3.7 1.7 1.7 4.7 0.9 3.1 5.8 1.6 0.2 0.0 5.7 29.5 0.5 3.5 1.4 1.1 2.4 0.6 6.6 2.3 2.4 1.7 2.9 0.6 2.6 3.1 9.4 2.9 2.5 2.2 9.9 3.1 2.4 14.8 8.4 2.8 1.9 0.5 0.7 1.3 0.6 2.9 2.9 2.7 5.0 1.4 4.2 9.3 10.5 2.7 7.8 3.6 2.1 5.9 4.4 4.8 3.5 2.5 5.8 5.6 3.0 20.0 8.4 3.2 1.0 7.1 2.2 8.3 21.6 32.9 12.2 9.0 7.9 12.8 9.7 11.0 13.7 RPS6KA6 RSK4 ENSG00000072133 "Ribosomal protein S6 kinase A6" Q9UK32 X 84058346-84187907 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 20.7" "Cell line enhanced" "Detected in many" "NTERA-2: 10.8;PC-3: 11.7;RH-30: 14.4;SH-SY5Y: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002852, HPA003904" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria "Nucleoplasm, Mitochondria" Nucleoli "HPA002852: AB_1079854, HPA003904: AB_1079853" "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (3.44e-1)" "unprognostic (4.93e-4)" "unprognostic (1.71e-1)" "unprognostic (3.04e-3)" "unprognostic (2.09e-2)" "unprognostic (2.50e-1)" "unprognostic (2.86e-1)" "unprognostic (4.88e-2)" "unprognostic (3.38e-3)" "unprognostic (2.88e-1)" "unprognostic (2.12e-9)" "unprognostic (4.44e-3)" "unprognostic (1.30e-2)" "unprognostic (2.34e-2)" "unprognostic (8.49e-3)" 0.7 2.9 5.9 1.0 12.2 0.0 2.3 4.7 5.1 3.1 4.5 1.1 20.7 1.7 2.7 4.0 1.5 4.0 1.9 1.2 5.1 2.9 9.2 0.9 0.8 0.2 1.5 3.3 4.9 3.4 13.5 9.1 0.5 4.4 4.3 3.7 1.5 3.0 15.0 1.4 2.3 2.0 1.7 1.0 0.6 2.4 2.6 2.7 0.8 14.5 0.9 0.6 3.3 2.3 1.2 0.8 2.4 0.5 0.7 2.8 0.1 0.0 3.6 3.5 0.0 3.4 3.4 0.0 7.5 4.0 3.4 2.8 2.7 3.0 0.0 0.0 4.1 0.1 9.0 6.0 7.9 0.0 4.5 0.0 0.1 0.0 3.0 0.0 0.0 1.9 0.0 0.0 3.7 0.8 0.0 0.1 2.7 0.0 1.3 0.1 10.8 11.7 0.0 14.4 0.0 0.5 8.3 0.0 11.5 0.0 4.2 0.0 1.9 0.0 0.0 0.1 4.3 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 2.4 0.4 0.5 0.5 0.3 0.4 1.2 0.4 0.7 0.8 0.6 0.4 0.4 1.1 0.7 0.5 0.4 2.8 0.1 5.9 12.2 4.7 5.1 5.1 2.9 1.5 3.3 4.4 2.7 RPS6KB1 "p70(S6K)-alpha, PS6K, S6K1, STK14A" ENSG00000108443 "Ribosomal protein S6 kinase B1" P23443 17 59893046-59950564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "MCF7: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003838, CAB018346, HPA039442" Approved Supported Nucleoplasm Nucleoplasm "CAB003838: AB_562325, CAB018346: AB_632156, HPA039442: " "unprognostic (2.25e-1)" "unprognostic (4.52e-2)" "unprognostic (1.91e-3)" "unprognostic (1.35e-2)" "unprognostic (9.81e-2)" "unprognostic (1.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.70e-1)" "unprognostic (5.86e-2)" "unprognostic (1.66e-1)" "unprognostic (3.67e-1)" "unprognostic (1.76e-2)" "prognostic unfavourable (5.09e-7)" "unprognostic (3.45e-1)" "unprognostic (2.09e-1)" "unprognostic (3.98e-2)" "unprognostic (1.52e-3)" 18.4 18.3 16.6 23.2 19.5 20.5 18.4 25.7 24.2 18.1 18.2 13.1 18.4 13.1 19.6 16.5 25.4 14.5 14.9 14.2 15.7 12.6 13.5 20.0 14.8 17.3 20.3 17.5 21.6 22.3 24.5 18.9 20.3 17.6 16.7 15.0 10.1 17.3 21.5 50.3 15.8 14.1 19.3 19.8 17.6 17.5 10.7 20.0 17.8 16.8 18.4 22.0 18.5 20.8 8.9 12.8 25.9 11.1 9.4 13.5 8.3 10.6 10.4 8.9 8.4 6.1 9.0 6.7 9.9 9.2 8.7 9.7 8.5 5.3 12.9 12.3 8.2 5.5 11.7 8.9 14.0 7.1 13.1 8.8 6.8 9.7 9.1 13.6 8.9 9.1 6.8 10.1 7.5 11.3 11.7 8.3 6.4 74.4 16.1 5.8 6.0 8.0 9.5 15.0 12.1 7.2 7.9 6.5 7.8 8.3 4.8 5.2 9.5 7.5 9.7 8.5 14.1 6.9 13.1 15.0 12.7 14.5 6.4 8.4 6.7 25.9 10.1 9.0 11.4 10.2 13.5 8.9 10.5 13.0 12.8 8.6 12.3 12.9 10.0 9.4 11.1 8.0 9.5 8.3 16.6 19.5 25.7 24.2 15.7 12.6 20.3 17.5 17.6 20.0 RPS6KB2 "KLS, P70-BETA, p70S6Kb, STK14B" ENSG00000175634 "Ribosomal protein S6 kinase B2" Q9UBS0 11 67428460-67435408 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010010, CAB019404" Approved Supported Cytosol Cytosol "CAB019404: AB_331355, HPA010010: AB_1856469" "unprognostic (1.38e-1)" "unprognostic (2.36e-3)" "unprognostic (8.50e-2)" "unprognostic (2.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-1)" "unprognostic (9.01e-3)" "unprognostic (5.10e-2)" "unprognostic (1.22e-1)" "unprognostic (9.49e-3)" "unprognostic (7.66e-2)" "unprognostic (2.79e-2)" "prognostic unfavourable (2.03e-7)" "unprognostic (1.28e-2)" "unprognostic (1.55e-1)" "unprognostic (2.12e-1)" "unprognostic (2.66e-1)" 8.7 14.1 8.5 12.8 9.2 18.0 11.2 12.9 11.5 13.1 13.0 12.5 12.3 19.8 10.2 10.1 36.1 11.0 10.7 10.7 8.8 4.2 11.3 27.8 10.7 12.0 11.4 8.7 9.5 18.7 9.6 11.7 13.8 8.7 17.2 9.9 11.7 18.1 15.8 25.0 41.4 17.7 8.8 7.6 18.6 17.1 7.5 8.8 21.8 11.4 28.6 21.8 10.1 15.6 15.7 27.1 16.4 28.3 17.8 20.7 20.2 21.7 16.5 9.0 15.2 4.2 8.1 11.8 10.5 13.2 19.7 13.7 25.7 14.6 8.0 18.3 10.3 16.2 10.1 16.0 8.0 13.8 27.0 12.9 21.0 20.9 14.2 16.3 16.0 10.3 16.9 10.4 10.7 14.6 20.7 21.5 9.9 33.3 25.1 25.7 9.7 21.2 18.6 12.5 38.0 9.1 12.5 13.6 14.6 10.8 30.1 22.4 35.4 13.6 6.1 10.3 11.0 24.8 11.7 19.3 15.8 12.9 16.9 10.3 12.8 9.7 22.6 16.4 15.7 25.2 15.9 15.7 14.9 15.3 27.1 14.3 10.9 11.9 15.1 17.8 28.3 18.7 20.7 20.2 8.5 9.2 12.9 11.5 8.8 4.2 11.4 8.7 8.7 8.8 RPS6KC1 humS6PKh1 ENSG00000136643 "Ribosomal protein S6 kinase C1" Q96S38 1 213051233-213274773 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026531, HPA031565" Approved Enhanced Endosomes,Lysosomes "Endosomes, Lysosomes" "HPA026531: AB_10601497, HPA031565: " "unprognostic (3.90e-2)" "unprognostic (5.90e-2)" "unprognostic (3.22e-1)" "unprognostic (4.88e-2)" "unprognostic (2.42e-1)" "unprognostic (9.81e-2)" "unprognostic (1.32e-2)" "unprognostic (1.64e-1)" "unprognostic (4.10e-2)" "unprognostic (3.34e-1)" "unprognostic (4.18e-1)" "unprognostic (5.11e-2)" "prognostic unfavourable (2.70e-4)" "unprognostic (8.10e-2)" "unprognostic (5.48e-2)" "unprognostic (2.98e-2)" "unprognostic (4.44e-2)" 12.0 14.1 15.6 10.0 19.4 6.4 17.1 13.5 19.4 14.1 13.1 12.6 8.8 9.2 15.9 8.4 10.3 11.8 11.6 9.4 17.3 15.6 9.8 10.8 13.6 7.5 17.8 16.8 14.4 13.5 19.9 16.7 12.3 15.3 17.6 10.1 7.3 8.9 17.7 14.1 6.7 8.7 18.5 22.3 11.0 12.5 26.5 13.2 6.8 10.4 6.1 7.8 14.6 16.0 2.5 8.7 13.7 6.8 4.0 3.3 2.2 7.4 6.4 10.6 11.4 10.6 15.7 9.3 9.8 14.4 15.2 17.5 5.2 8.3 4.7 6.6 14.7 6.1 12.8 8.0 11.6 9.9 4.7 12.7 7.6 7.2 9.8 8.0 15.1 10.3 6.9 13.3 7.3 12.6 16.3 7.3 15.5 4.0 3.3 2.6 15.3 7.3 4.0 10.0 4.6 7.0 7.5 6.2 16.1 10.6 8.4 14.0 12.0 3.4 11.7 10.4 9.6 11.9 6.4 4.3 8.3 3.6 4.4 3.1 10.6 13.7 4.6 3.3 2.8 6.8 2.3 2.5 2.3 2.4 8.7 1.9 1.5 3.3 0.5 4.0 6.3 1.0 1.6 2.2 15.6 19.4 13.5 19.0 17.3 15.6 17.8 16.8 15.3 13.2 RPS6KL1 MGC11287 ENSG00000198208 "Ribosomal protein S6 kinase like 1" Q9Y6S9 14 74903954-74923396 "Enzymes, Predicted intracellular proteins" "Kinase, Ribonucleoprotein, Ribosomal protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.1" "Cell line enhanced" "Detected in many" "HMC-1: 12.8;SCLC-21H: 24.5;SK-BR-3: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.0;naive CD4 T-cell: 1.9;naive CD8 T-cell: 2.0;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 26 "B-cells: 2.0;dendritic cells: 5.4;T-cells: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027451, HPA027794" Approved Approved Nucleoplasm Nucleoplasm "HPA027451: AB_10599304, HPA027794: AB_10602098" "unprognostic (2.71e-2)" "unprognostic (9.33e-3)" "unprognostic (3.36e-1)" "unprognostic (1.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.44e-2)" "unprognostic (7.49e-4)" "unprognostic (2.06e-1)" "unprognostic (1.54e-1)" "unprognostic (4.09e-3)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "unprognostic (1.33e-2)" "unprognostic (1.14e-1)" "unprognostic (7.03e-2)" "unprognostic (7.52e-2)" 4.2 7.5 14.7 2.3 13.6 4.2 5.7 18.2 29.1 2.1 4.8 9.0 2.2 3.8 5.1 8.8 5.3 2.5 3.7 10.2 14.3 13.7 2.3 2.1 2.5 2.5 11.1 15.3 1.5 6.7 4.0 10.6 1.4 8.4 2.8 5.6 5.9 3.2 5.4 12.7 1.2 2.8 6.9 8.8 1.7 2.0 11.4 6.8 0.0 3.8 1.2 2.5 1.9 0.8 2.0 5.4 0.1 0.0 0.0 2.0 0.1 2.3 0.3 0.9 3.7 0.1 0.0 4.4 0.4 0.2 1.8 0.5 5.5 1.6 0.0 3.4 0.7 0.3 1.8 0.3 2.3 0.0 0.8 1.9 0.7 4.1 4.6 2.2 12.8 0.3 3.2 2.0 0.0 5.8 2.6 0.7 0.1 7.5 0.0 0.7 0.8 3.6 1.8 0.0 7.1 1.8 0.0 24.5 3.0 0.2 14.1 2.3 1.3 1.5 3.9 0.1 0.2 3.0 0.0 9.9 5.2 5.2 1.3 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.2 2.0 0.4 0.1 0.0 0.4 1.9 2.0 0.1 0.0 0.0 5.4 0.0 0.1 14.7 13.6 18.2 18.2 14.3 13.7 11.1 15.3 8.4 6.8 RRM1 ENSG00000167325 "Ribonucleotide reductase catalytic subunit M1" P23921 11 4094707-4138876 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Allosteric enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 78.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022093, HPA057265, HPA064297" Enhanced Enhanced Cytosol 13000 Cytosol "CAB022093: , HPA057265: , HPA064297: " "unprognostic (4.47e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-3)" "unprognostic (3.65e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-1)" "prognostic unfavourable (1.53e-4)" "unprognostic (1.31e-2)" "unprognostic (3.43e-2)" "unprognostic (6.90e-2)" "unprognostic (1.06e-3)" "unprognostic (4.21e-2)" "unprognostic (6.88e-3)" "unprognostic (9.20e-3)" "unprognostic (6.16e-2)" "unprognostic (8.41e-2)" "unprognostic (9.93e-3)" 13.9 25.3 8.0 15.2 12.2 18.5 14.4 18.0 12.6 15.7 15.9 11.1 11.5 11.9 13.0 9.8 25.4 10.7 8.7 11.9 7.9 9.0 9.2 13.1 11.0 20.2 9.0 10.3 13.6 10.7 24.2 11.2 22.7 18.4 14.0 18.9 12.0 15.4 10.7 28.3 26.8 12.5 17.5 10.7 12.4 13.8 10.5 9.1 78.6 9.8 28.0 27.1 17.5 18.5 5.6 4.3 3.3 8.3 5.7 24.3 6.0 45.4 24.7 40.5 23.5 6.2 12.4 15.7 41.9 20.8 47.7 49.2 22.2 34.6 49.2 10.2 20.9 36.6 37.5 30.1 56.5 24.2 39.8 25.0 37.1 17.3 2.5 42.8 18.4 5.8 8.1 26.1 18.8 22.8 32.6 23.3 39.7 20.6 50.3 9.3 25.6 25.1 40.8 31.7 17.6 13.1 12.9 34.7 19.0 36.9 22.3 6.7 22.0 15.0 13.0 44.9 23.5 44.4 30.7 15.2 21.1 53.8 24.9 28.7 27.8 3.3 2.5 2.6 7.7 6.5 13.3 5.6 14.2 10.7 4.3 3.5 11.3 9.2 0.0 5.7 8.3 2.7 24.3 6.0 8.0 12.2 18.0 12.6 7.9 9.0 9.0 10.3 18.4 9.1 RRM2 ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10131419 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 120.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.4" "Lineage enriched" "Detected in many" 6 "T-cells: 10.4" HPA056994 Enhanced Supported Cytosol Cytosol "HPA056994: " "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavourable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavourable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavourable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 4.7 2.2 0.4 32.6 0.4 29.0 4.2 0.4 0.9 3.5 9.3 0.4 0.4 5.2 2.1 1.7 21.6 0.7 5.0 3.3 0.4 0.5 2.0 3.9 5.7 16.4 0.6 0.1 0.9 2.9 0.0 0.7 5.4 0.3 1.0 10.6 0.1 2.9 0.0 0.5 2.8 11.3 3.2 0.8 19.8 5.4 8.0 0.0 120.9 0.8 22.3 33.1 3.8 5.2 1.4 0.3 0.6 0.2 1.8 10.4 2.6 29.1 17.7 25.0 17.1 2.2 4.1 24.8 47.7 23.6 34.1 37.1 29.5 14.0 26.8 6.6 14.9 14.3 40.5 24.6 41.8 60.0 15.6 51.6 17.0 26.0 0.1 38.2 24.8 1.4 0.5 41.7 3.5 27.5 21.6 79.5 42.4 22.0 42.2 20.5 20.2 20.7 31.8 54.6 18.4 16.7 22.2 24.8 20.4 39.2 27.9 4.8 15.0 6.9 9.6 26.1 38.0 19.5 66.8 51.6 40.5 54.7 18.5 32.4 37.5 0.3 0.1 0.1 3.7 0.0 0.0 1.4 2.6 2.9 0.2 0.4 0.2 1.2 0.6 1.8 0.2 0.3 10.4 2.6 0.4 0.4 0.4 0.9 0.4 0.5 0.6 0.1 0.3 0.0 RRM2B p53R2 ENSG00000048392 "Ribonucleotide reductase regulatory TP53 inducible subunit M2B" Q7LG56 8 102204502-102239118 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, DNA replication" Oxidoreductase "Disease mutation, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006854, HPA028812" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB006854: , HPA028812: AB_10602246" "unprognostic (7.76e-3)" "unprognostic (4.14e-2)" "unprognostic (9.41e-3)" "unprognostic (3.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.28e-1)" "unprognostic (5.51e-2)" "unprognostic (1.35e-2)" "unprognostic (1.66e-1)" "unprognostic (9.40e-2)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-2)" "unprognostic (4.32e-1)" "unprognostic (1.47e-1)" "unprognostic (2.52e-1)" "unprognostic (7.17e-2)" 11.8 18.6 11.7 11.5 11.4 4.3 9.3 8.5 13.5 9.5 10.1 9.8 9.5 10.2 8.2 10.8 8.0 9.7 8.2 11.3 17.5 12.8 17.5 15.1 15.8 12.6 14.9 10.6 9.7 9.5 34.7 24.8 11.6 23.1 11.2 11.1 7.7 9.7 10.9 34.6 7.4 7.6 8.2 26.1 10.6 7.1 6.6 9.4 6.3 37.1 8.1 13.1 10.7 7.0 7.4 6.2 18.3 8.4 3.0 3.3 2.8 5.6 10.1 12.0 7.1 17.0 16.4 9.6 13.2 16.0 7.1 8.3 3.6 4.6 36.4 12.5 14.6 2.1 5.8 13.4 10.1 5.9 6.3 9.1 4.3 7.6 13.8 2.8 19.5 20.8 25.3 7.8 11.9 19.8 6.7 5.6 22.7 5.6 4.8 5.3 6.7 7.5 3.1 4.9 7.3 16.5 6.5 3.0 6.0 6.9 3.7 7.9 9.9 6.3 15.1 11.0 21.4 7.6 3.6 5.9 5.4 33.1 16.2 4.3 11.6 10.0 5.1 5.3 2.2 4.5 3.3 5.6 2.0 2.8 6.2 7.4 2.3 2.5 18.3 3.0 8.4 1.8 1.4 2.8 11.7 11.4 8.5 13.5 17.5 12.8 14.9 10.6 23.1 9.4 RTCA "RPC, RTC1, RTCD1" ENSG00000137996 "RNA 3'-terminal phosphate cyclase" O00442 1 100266207-100292769 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027982, HPA027990, HPA028151, HPA028331" Uncertain Enhanced Nucleoplasm 8700 Nucleoplasm "HPA027982: AB_10601769, HPA027990: AB_2672452, HPA028151: AB_10602099, HPA028331: " "unprognostic (4.79e-2)" "unprognostic (1.17e-2)" "unprognostic (3.97e-2)" "unprognostic (3.82e-2)" "unprognostic (6.76e-2)" "unprognostic (4.12e-2)" "prognostic unfavourable (2.76e-5)" "unprognostic (9.55e-3)" "unprognostic (3.64e-2)" "unprognostic (1.12e-2)" "unprognostic (2.46e-1)" "unprognostic (8.09e-3)" "unprognostic (3.74e-3)" "unprognostic (2.10e-2)" "unprognostic (1.44e-1)" "unprognostic (3.59e-1)" "unprognostic (2.94e-2)" 20.9 25.0 19.4 17.8 24.9 25.5 20.0 22.6 31.7 14.7 22.9 20.3 19.9 31.7 14.2 26.0 27.0 13.4 19.9 25.5 20.0 21.0 31.7 23.0 16.1 21.8 21.5 20.7 13.3 27.7 21.1 17.2 21.2 33.1 20.9 22.2 14.1 18.5 17.4 35.4 14.6 37.8 15.4 20.5 24.2 21.8 12.2 12.4 25.0 18.3 20.2 20.8 18.7 17.5 9.6 8.0 8.2 19.6 11.0 20.1 7.7 21.5 11.2 11.0 14.8 14.0 22.8 30.2 25.6 12.5 16.7 14.4 18.2 10.9 22.1 19.5 16.2 11.0 13.5 12.1 20.2 22.1 11.3 14.6 12.8 22.9 21.6 26.5 23.1 18.5 19.1 21.9 29.2 20.7 25.0 33.7 25.2 7.1 13.6 20.6 16.9 21.7 9.8 19.8 9.7 20.5 17.7 8.9 11.1 16.5 24.0 35.0 5.2 34.0 18.0 15.8 11.1 24.7 30.7 19.6 19.6 17.7 33.3 23.0 9.4 8.2 9.1 7.5 10.8 11.3 13.8 9.6 10.0 12.8 8.0 7.1 9.3 10.5 4.4 11.0 19.6 7.6 20.1 7.7 19.4 24.9 22.6 31.7 20.0 21.0 21.5 20.7 33.1 12.4 RTCB "C22orf28, FAAP, HSPC117" ENSG00000100220 "RNA 2',3'-cyclic phosphate and 5'-OH ligase" Q9Y3I0 22 32387582-32412255 "Enzymes, Predicted intracellular proteins" "tRNA processing" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000535, HPA001103" Supported Supported Nucleoplasm,Vesicles,Cytosol 43000 Nucleoplasm "Vesicles, Cytosol" "HPA000535: , HPA001103: AB_1078351" "unprognostic (1.84e-1)" "unprognostic (6.48e-2)" "unprognostic (1.07e-2)" "unprognostic (2.71e-3)" "unprognostic (7.21e-3)" "unprognostic (1.43e-2)" "unprognostic (1.75e-3)" "unprognostic (1.49e-1)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (5.07e-2)" "prognostic favourable (4.25e-5)" "unprognostic (6.91e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" 26.4 30.1 20.1 20.4 29.7 15.1 29.2 22.9 34.5 25.7 35.6 35.2 32.7 51.6 29.7 25.8 30.8 26.9 22.9 26.4 19.6 24.6 42.4 55.1 23.1 22.7 29.1 26.2 29.0 29.4 38.4 29.9 33.7 36.7 27.0 42.3 27.1 29.9 28.6 40.9 46.6 61.7 31.8 24.4 29.3 29.7 30.8 25.5 32.0 32.7 30.1 46.6 26.5 24.2 44.6 51.5 29.0 47.7 37.0 40.5 44.0 31.7 28.6 35.9 26.9 31.4 23.5 28.6 27.9 33.7 44.7 42.5 37.1 13.0 7.9 18.7 32.5 21.7 41.0 40.5 57.9 39.8 41.2 22.5 24.3 33.7 21.6 52.5 20.6 23.0 26.9 44.1 43.0 40.1 26.6 22.5 32.5 26.5 22.3 18.2 20.5 26.2 34.7 38.8 40.6 30.7 27.7 37.1 20.5 30.2 19.6 35.4 21.5 20.5 30.1 24.7 36.4 21.4 26.7 15.7 12.5 28.5 25.5 23.8 32.1 29.0 43.5 27.4 31.7 47.7 35.5 44.6 33.3 33.0 51.5 43.6 39.9 34.6 4.3 37.0 35.5 28.9 40.5 44.0 20.1 29.7 22.9 34.5 19.6 24.6 29.1 26.2 36.7 25.5 RTEL1 "bK3184A7.3, C20orf41, DKFZP434C013, KIAA1088, NHL, RTEL" ENSG00000258366 "Regulator of telomere elongation helicase 1" Q9NZ71 20 63657810-63696253 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Disease mutation, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "HPA020622, HPA067329, HPA078328" Approved "Nuclear speckles,Nuclear bodies" "Nuclear speckles, Nuclear bodies" "HPA020622: , HPA067329: , HPA078328: " "unprognostic (3.63e-2)" "unprognostic (8.08e-3)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.27e-1)" "unprognostic (9.30e-3)" "unprognostic (2.59e-1)" "unprognostic (3.64e-2)" "unprognostic (3.30e-2)" "unprognostic (9.05e-2)" "unprognostic (4.09e-2)" "unprognostic (9.50e-2)" "unprognostic (8.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" "unprognostic (8.84e-2)" 8.4 14.3 9.4 11.5 12.4 14.2 7.9 25.6 11.8 9.1 11.1 11.2 10.9 9.8 15.4 7.4 7.0 9.5 9.3 6.2 8.0 6.9 7.1 7.2 8.9 7.8 7.5 12.1 10.6 17.8 7.2 18.2 9.8 8.2 10.2 4.8 10.2 12.9 10.2 10.2 8.2 10.1 8.8 4.4 11.6 10.4 17.6 8.9 9.1 11.9 4.9 9.5 9.3 9.0 1.7 3.6 0.0 3.3 0.4 3.0 2.4 5.2 7.2 5.2 10.0 1.1 1.2 9.6 10.9 2.9 17.0 4.5 14.4 4.5 7.1 5.7 3.3 9.9 3.5 7.1 4.1 3.5 7.3 8.7 12.5 13.7 3.8 8.5 16.0 1.5 4.0 4.2 5.2 5.8 10.8 6.7 3.8 5.6 13.2 11.0 5.1 15.2 10.6 4.9 7.3 2.7 6.5 10.3 6.2 6.1 17.8 1.3 4.7 9.6 7.7 19.3 6.3 6.6 8.3 6.2 2.6 4.4 4.7 6.0 6.7 0.0 2.7 0.0 3.0 3.3 1.6 0.9 1.7 2.0 3.6 1.7 2.9 1.1 0.0 0.4 2.6 3.2 1.4 2.4 9.4 12.4 25.6 11.8 8.0 6.9 7.5 12.1 8.2 8.9 RUVBL1 "ECP54, INO80H, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49a" ENSG00000175792 "RuvB like AAA ATPase 1" Q9Y265 3 128064778-128153914 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Growth regulation, Mitosis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019947, HPA019948" Enhanced Supported Nucleoplasm,Cytosol 47000 "Nucleoplasm, Cytosol" "HPA019947: AB_1856516, HPA019948: AB_1856514" "unprognostic (7.40e-2)" "unprognostic (2.17e-1)" "unprognostic (1.28e-1)" "unprognostic (4.73e-2)" "unprognostic (3.55e-1)" "unprognostic (2.66e-2)" "prognostic unfavourable (1.21e-8)" "unprognostic (2.43e-2)" "unprognostic (3.31e-2)" "unprognostic (1.39e-1)" "unprognostic (2.25e-2)" "unprognostic (7.39e-2)" "unprognostic (2.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (1.61e-1)" "unprognostic (9.27e-2)" 17.6 15.1 10.7 15.8 14.2 11.9 13.9 7.9 14.0 12.5 11.6 12.9 14.3 8.4 19.2 11.4 19.2 37.3 11.3 18.6 11.4 13.6 20.9 13.7 12.9 18.7 10.0 9.8 15.4 13.6 26.5 14.2 19.9 13.0 12.0 14.1 11.5 10.2 12.0 12.9 11.8 10.2 16.1 8.8 21.9 10.9 44.7 10.3 33.4 15.2 18.1 23.9 12.6 15.0 10.6 8.7 1.5 7.9 10.9 20.2 7.2 26.7 24.3 14.9 24.3 11.7 11.4 19.6 13.1 11.3 25.3 17.5 25.4 15.9 38.0 13.1 12.5 21.3 39.8 27.8 29.5 15.5 19.5 31.5 14.1 17.0 12.1 29.4 10.1 11.6 14.7 21.3 27.4 16.9 25.8 8.9 14.4 38.1 31.5 22.3 37.6 20.8 25.9 18.1 26.4 15.1 10.1 25.1 22.5 14.5 12.0 20.1 21.8 21.8 10.9 11.5 14.1 17.3 19.8 9.1 14.5 37.3 14.2 18.1 14.4 0.8 4.8 1.5 11.3 7.9 14.6 10.6 13.6 14.0 7.7 10.2 11.5 12.8 0.2 10.9 7.4 8.7 20.2 7.2 10.7 14.2 7.9 14.0 11.4 13.6 10.0 9.8 13.0 10.3 RUVBL2 "ECP51, INO80J, Reptin52, RVB2, TIH2, TIP48, TIP49b" ENSG00000183207 "RuvB like AAA ATPase 2" Q9Y230 19 48993448-49015995 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 59.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012432, HPA042880, HPA067966" Enhanced Supported Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Cytosol" Centrosome "CAB012432: , HPA042880: AB_2678210, HPA067966: AB_2685933" "unprognostic (1.71e-1)" "unprognostic (9.06e-3)" "unprognostic (3.51e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (2.47e-2)" "prognostic unfavourable (9.28e-4)" "unprognostic (7.06e-3)" "unprognostic (6.25e-2)" "unprognostic (3.28e-1)" "unprognostic (8.13e-2)" "unprognostic (7.58e-2)" "unprognostic (2.81e-2)" "unprognostic (2.21e-2)" "unprognostic (7.61e-3)" "unprognostic (1.61e-1)" "unprognostic (2.58e-1)" 6.9 5.3 6.7 7.5 7.1 13.4 4.8 8.2 10.4 4.8 9.9 7.6 6.3 11.2 8.3 5.5 16.1 5.5 7.2 9.1 6.9 6.0 7.6 10.3 5.5 8.2 7.7 8.1 6.5 8.7 1.6 6.4 5.5 6.7 6.0 3.2 6.5 10.0 6.6 27.8 7.7 10.0 3.7 7.1 6.9 10.7 59.0 5.8 14.6 8.8 9.4 8.1 6.4 12.9 12.6 16.4 5.6 14.3 11.0 12.5 15.2 28.8 29.7 3.5 20.0 1.5 2.7 9.4 15.6 6.8 17.9 11.8 15.4 12.5 27.1 12.1 3.1 15.3 2.1 10.2 2.1 16.4 12.2 17.7 8.9 7.8 5.0 34.7 12.4 3.1 2.0 4.0 2.1 6.6 30.6 11.5 1.6 5.9 30.6 4.1 10.7 4.4 25.4 16.0 17.4 3.2 11.1 14.2 20.5 15.7 13.1 5.6 11.6 13.3 9.7 11.4 16.7 7.5 38.6 23.4 26.7 28.0 8.4 17.0 16.3 5.6 14.3 4.2 11.1 11.1 11.2 10.9 11.1 9.1 16.4 12.6 12.2 8.0 1.0 11.0 10.8 12.5 12.5 15.2 6.7 7.1 8.2 10.4 6.9 6.0 7.7 8.1 6.7 5.8 SARDH "DMGDHL1, SDH" ENSG00000123453 "Sarcosine dehydrogenase" Q9UL12 9 133663560-133739955 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 25.3;liver: 52.8;pancreas: 39.4" "Cell line enhanced" "Detected in many" "AN3-CA: 10.9;Hep G2: 18.4;MOLT-4: 13.3;RH-30: 11.4;RPMI-8226: 23.0;SH-SY5Y: 9.2" "Cancer enriched" "Detected in many" 8 "liver cancer: 18.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 4.1;naive CD4 T-cell: 8.4;T-reg: 9.7" "Lineage enriched" "Detected in single" 15 "T-cells: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057267, HPA058086" Approved Approved Mitochondria 190000 Mitochondria "HPA057267: , HPA058086: " "unprognostic (3.64e-2)" "unprognostic (4.87e-2)" "unprognostic (2.31e-2)" "unprognostic (1.38e-1)" "prognostic unfavourable (4.62e-4)" "unprognostic (5.83e-2)" "unprognostic (1.42e-3)" "unprognostic (2.21e-1)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "unprognostic (7.74e-3)" "unprognostic (2.78e-1)" "unprognostic (3.48e-1)" "unprognostic (9.73e-2)" "unprognostic (1.30e-2)" 0.5 1.1 1.7 1.0 1.8 0.3 0.4 0.8 1.9 0.9 0.5 1.1 2.9 0.8 1.4 25.3 0.3 0.9 1.2 1.1 1.1 1.4 5.8 52.8 1.3 1.7 1.2 2.1 3.4 39.4 2.0 1.9 0.3 1.2 1.4 0.1 3.7 8.2 0.9 0.3 0.2 0.6 0.6 0.6 0.7 1.2 1.1 0.8 2.2 0.8 0.2 1.2 0.6 0.6 0.4 0.3 0.6 0.1 0.1 9.7 1.6 0.0 0.1 0.8 10.9 0.0 0.3 1.4 0.1 0.4 0.5 0.7 0.2 0.1 0.0 1.5 0.1 0.0 0.0 0.2 0.4 0.0 0.2 1.5 0.0 18.4 1.2 0.0 0.2 2.6 0.0 1.3 0.0 0.1 0.0 0.2 6.9 1.9 13.3 1.4 1.7 0.1 0.9 11.4 23.0 0.0 0.1 1.0 9.2 0.0 0.3 2.3 1.5 0.1 0.0 2.1 1.9 0.2 0.0 0.1 0.0 0.7 1.3 0.8 0.0 0.1 0.1 0.1 0.4 0.0 1.0 0.0 4.1 1.0 0.0 0.4 8.4 1.5 0.6 0.1 0.0 0.3 9.7 1.6 1.7 1.8 0.8 1.9 1.1 1.4 1.2 2.1 1.2 0.8 SARS SERS ENSG00000031698 "Seryl-tRNA synthetase" P49591 1 109213918-109238169 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "Aminoacyl-tRNA synthetase, DNA-binding, Ligase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016939, HPA064668" Uncertain Enhanced Cytosol 100000 Cytosol "HPA016939: AB_1856585, HPA064668: " "unprognostic (4.92e-2)" "unprognostic (2.61e-1)" "unprognostic (5.87e-2)" "unprognostic (6.78e-2)" "prognostic favourable (9.47e-4)" "prognostic unfavourable (5.75e-4)" "prognostic unfavourable (6.13e-5)" "unprognostic (3.02e-1)" "unprognostic (1.77e-1)" "unprognostic (2.68e-2)" "unprognostic (3.23e-1)" "unprognostic (2.06e-1)" "unprognostic (1.69e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-1)" "unprognostic (3.85e-2)" "unprognostic (3.45e-3)" 35.8 42.6 46.1 28.2 45.9 16.3 38.3 42.6 60.6 40.1 37.6 31.2 30.9 33.5 39.4 36.0 42.0 39.6 28.7 43.9 55.9 47.3 37.6 58.6 44.5 28.8 46.4 56.0 44.4 68.7 55.3 40.1 44.9 64.1 34.3 41.0 22.0 54.2 42.3 72.3 46.1 31.1 42.9 41.0 29.4 46.0 20.9 35.0 25.3 75.0 32.9 38.7 41.8 60.4 54.3 45.9 48.6 48.3 41.0 66.1 88.9 32.7 12.9 24.8 37.3 37.3 33.9 42.7 34.5 35.8 30.0 37.5 24.9 10.1 35.4 17.9 48.7 18.0 38.6 48.8 35.0 25.0 23.5 13.7 16.0 18.0 75.0 17.2 15.4 41.6 85.5 35.4 77.0 35.7 31.3 44.4 29.2 31.4 19.1 8.8 10.3 30.5 15.8 31.7 15.8 22.8 17.5 34.5 18.3 16.5 26.7 93.6 15.1 20.6 28.1 17.9 22.6 25.4 24.1 33.9 13.7 29.0 56.5 18.9 60.8 35.6 44.5 48.6 56.0 48.2 58.4 54.3 59.3 55.4 45.9 52.5 61.8 57.7 21.3 41.0 48.3 29.6 66.1 88.9 46.1 45.9 42.6 60.6 55.9 47.3 46.4 56.0 64.1 35.0 SARS2 "FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS" ENSG00000104835 "Seryl-tRNA synthetase 2, mitochondrial" Q9NP81 19 38915266-38930896 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "HPA052730, HPA056957" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria "Nucleoplasm, Mitochondria" Vesicles "HPA052730: , HPA056957: " "unprognostic (3.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (3.53e-3)" "unprognostic (1.08e-1)" "unprognostic (1.88e-3)" "unprognostic (4.38e-3)" "unprognostic (1.22e-1)" "unprognostic (2.57e-2)" "unprognostic (8.62e-3)" "unprognostic (8.36e-2)" "unprognostic (1.67e-1)" "unprognostic (5.62e-3)" "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.69e-2)" 5.8 16.5 9.9 7.2 12.8 11.1 7.4 10.7 20.4 8.0 9.2 11.3 11.4 12.3 9.0 9.4 12.9 11.5 8.2 12.3 8.3 8.6 13.4 20.6 6.3 11.0 10.9 7.8 9.5 14.4 11.2 11.4 10.7 15.0 11.0 8.5 11.8 13.6 9.9 15.5 15.6 9.9 8.1 7.2 11.3 11.1 8.8 11.5 11.4 13.8 9.5 12.6 11.0 8.3 6.3 12.7 0.4 7.2 6.5 8.0 4.3 5.6 17.3 6.9 4.1 2.9 6.0 9.6 4.0 5.4 9.4 7.5 14.1 7.1 6.4 5.8 5.6 5.4 7.3 11.4 2.4 5.5 9.3 12.8 7.5 12.1 6.9 11.0 12.8 9.0 6.2 6.2 4.2 6.6 11.0 6.4 4.8 12.2 8.2 10.0 7.0 3.5 11.9 6.2 7.0 10.0 13.9 11.9 7.6 5.3 14.4 3.6 7.4 7.4 4.2 5.9 6.7 4.6 3.9 4.6 2.7 5.1 3.7 7.7 4.9 0.0 4.1 0.4 8.0 7.2 6.4 6.3 5.9 8.0 12.7 5.7 4.3 4.9 0.3 6.5 6.4 5.0 6.6 4.3 9.9 12.8 10.7 20.4 8.3 8.6 10.9 7.8 15.0 11.5 SAT1 "SAT, SSAT" ENSG00000130066 "Spermidine/spermine N1-acetyltransferase 1" P21673 X 23783173-23786226 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 71.3;hTERT-HME1: 109.8;RPTEC TERT1: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 206.1" "Group enriched" "Detected in all" 9 "granulocytes: 206.1;monocytes: 136.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB047343, HPA055312, CAB069914" Supported "CAB047343: , CAB069914: AB_830224, HPA055312: " "unprognostic (4.19e-2)" "unprognostic (3.92e-2)" "unprognostic (6.41e-2)" "prognostic favourable (2.87e-4)" "unprognostic (8.58e-2)" "unprognostic (7.90e-3)" "unprognostic (8.52e-3)" "unprognostic (2.22e-2)" "unprognostic (2.81e-1)" "unprognostic (1.18e-1)" "unprognostic (8.38e-3)" "unprognostic (2.23e-1)" "unprognostic (7.58e-2)" "unprognostic (5.13e-2)" "unprognostic (1.61e-1)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 93.5 40.5 34.2 73.0 60.5 177.2 57.2 14.2 38.9 49.2 56.5 24.6 143.2 82.2 43.9 51.9 56.9 36.8 80.6 81.5 53.7 27.7 79.2 116.1 163.6 67.3 31.9 22.2 26.5 32.3 19.3 74.4 185.7 100.2 51.0 49.9 39.3 110.6 173.3 14.4 25.4 65.5 23.5 100.8 108.6 64.5 25.6 27.1 23.0 102.7 41.1 60.6 52.4 29.6 7.3 19.0 206.1 136.4 1.8 13.2 34.6 7.8 15.9 4.0 6.3 34.5 14.1 11.0 11.5 19.4 2.8 6.7 7.5 23.2 13.1 21.2 2.7 11.9 2.1 71.3 10.5 4.3 9.7 6.3 6.9 63.5 44.4 6.1 6.1 29.2 54.5 22.3 109.8 23.6 2.6 11.6 8.3 7.4 4.4 27.6 2.7 7.3 3.8 2.6 15.6 91.3 16.2 1.1 1.1 11.8 26.9 22.7 4.1 1.3 8.8 23.5 1.1 14.0 5.6 4.9 1.1 2.9 14.0 3.6 4.4 25.8 42.0 26.9 4.1 110.5 2.6 7.3 4.9 3.3 19.0 4.7 2.9 3.3 206.1 1.8 136.4 9.4 13.2 34.6 34.2 60.5 14.2 38.9 53.7 27.7 31.9 22.2 100.2 27.1 SAT2 SSAT2 ENSG00000141504 "Spermidine/spermine N1-acetyltransferase family member 2" Q96F10 17 7626234-7627876 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 73.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022136, HPA057096" Enhanced "HPA022136: AB_1856592, HPA057096: AB_2683334" "unprognostic (2.61e-2)" "unprognostic (1.27e-2)" "unprognostic (3.23e-2)" "prognostic favourable (8.76e-6)" "unprognostic (2.18e-2)" "unprognostic (2.32e-1)" "unprognostic (7.20e-2)" "prognostic favourable (6.71e-4)" "unprognostic (4.14e-2)" "unprognostic (2.75e-1)" "prognostic favourable (6.05e-5)" "unprognostic (1.83e-1)" "unprognostic (6.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (1.50e-1)" "unprognostic (3.12e-2)" 11.3 43.9 14.8 6.3 16.7 6.4 11.0 11.3 17.4 12.5 33.4 9.2 10.8 51.5 11.7 14.9 8.9 10.2 11.3 14.5 13.4 9.8 49.6 73.2 9.1 8.9 18.3 17.1 19.9 20.0 11.3 13.7 5.5 15.2 11.5 9.2 13.9 16.2 13.6 12.0 7.9 47.9 10.1 10.5 12.5 13.3 11.7 16.8 2.7 18.5 11.9 7.3 9.9 13.3 8.6 18.4 5.5 25.6 6.6 11.8 12.9 7.5 11.6 10.1 19.2 15.0 18.6 1.3 5.3 18.4 11.6 15.1 3.7 3.9 1.5 3.0 5.0 6.7 6.3 5.1 7.5 2.2 19.3 1.6 6.2 19.2 19.5 0.0 5.5 24.3 12.3 6.8 4.7 17.0 1.0 2.4 12.3 0.6 0.1 1.6 4.0 8.0 2.9 5.0 1.8 17.4 8.6 1.1 10.0 5.2 10.2 9.6 6.4 1.6 8.3 5.5 4.0 0.1 7.7 5.0 4.2 0.2 19.9 2.2 8.5 4.6 25.6 5.5 8.9 17.1 10.5 8.6 7.7 9.1 18.4 8.3 11.8 8.4 1.6 6.6 8.8 8.3 11.2 12.9 14.8 16.7 11.3 17.4 13.4 9.8 18.3 17.1 15.2 16.8 SBK2 SGK069 ENSG00000187550 "SH3 domain binding kinase family member 2" P0C263 19 55529733-55537089 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 27 "heart muscle: 45.7;tongue: 20.8" "Cell line enhanced" "Detected in some" "A549: 4.3;Hep G2: 3.1;MCF7: 4.4;NTERA-2: 8.7;RH-30: 8.1;U-2 OS: 4.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030631 Enhanced "HPA030631: AB_10602088" "unprognostic (1.33e-1)" "unprognostic (1.85e-3)" "unprognostic (4.57e-1)" "unprognostic (3.49e-1)" "unprognostic (5.43e-3)" "unprognostic (4.18e-3)" "unprognostic (2.08e-1)" "unprognostic (6.58e-2)" "unprognostic (1.05e-1)" 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.7 20.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.4 1.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.3 4.4 0.0 0.0 8.7 0.0 0.0 8.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SBK3 SgK110 ENSG00000231274 "SH3 domain binding kinase family member 3" P0C264 19 55540656-55545543 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "heart muscle: 24.2" "Cell line enhanced" "Detected in some" "A549: 9.2;CACO-2: 3.2;CAPAN-2: 5.4;NTERA-2: 2.5;RH-30: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA078322 Approved Mitochondria Mitochondria "HPA078322: " "unprognostic (2.15e-1)" "unprognostic (1.99e-3)" "unprognostic (2.71e-1)" "unprognostic (1.39e-3)" "unprognostic (7.52e-2)" "unprognostic (2.83e-1)" "unprognostic (5.47e-5)" "unprognostic (4.64e-3)" "unprognostic (7.24e-2)" "unprognostic (1.65e-1)" "unprognostic (3.38e-1)" "unprognostic (3.08e-3)" "unprognostic (1.21e-2)" "unprognostic (4.92e-2)" "unprognostic (2.41e-1)" "unprognostic (1.79e-1)" 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.1 24.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.8 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.3 3.2 5.4 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.8 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.0 0.0 0.0 2.5 0.6 0.2 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 1.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292453-121308694 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 143.5" "Cell line enhanced" "Detected in all" "AF22: 53.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: , HPA070248: " "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavourable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavourable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favourable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" 10.9 15.3 16.9 5.5 18.4 2.7 23.3 10.4 26.9 9.4 9.4 17.8 24.5 17.4 6.8 30.1 19.5 7.2 7.4 9.4 18.7 19.6 19.7 143.5 10.1 5.5 20.8 17.8 7.8 8.9 17.5 14.7 6.3 40.8 40.3 8.6 8.2 9.5 24.0 3.9 7.7 13.4 7.6 43.4 4.1 8.8 9.7 16.0 3.7 10.4 8.2 8.1 14.0 14.6 6.0 9.8 7.5 6.3 6.8 10.0 3.8 7.1 3.6 53.9 11.5 21.0 18.2 7.6 8.0 15.1 5.4 9.6 22.5 26.6 6.7 25.4 8.7 26.7 16.8 20.3 5.3 3.3 22.9 10.0 23.5 17.9 17.1 6.3 3.4 14.9 16.7 17.1 17.6 8.2 6.5 9.8 24.9 7.4 2.5 8.2 16.8 11.4 3.5 13.6 5.7 38.0 32.0 14.2 8.0 18.4 4.2 10.5 16.8 10.9 15.5 5.2 8.4 9.2 3.7 1.8 3.1 9.0 2.0 13.9 9.0 7.5 4.8 1.2 5.0 6.3 8.5 6.0 6.8 6.0 8.5 6.0 10.0 9.5 0.4 6.8 4.5 9.8 6.9 3.8 16.9 18.4 10.4 26.9 18.7 19.6 20.8 17.8 40.8 16.0 SCD "FADS5, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347124-100364834 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 245.0;brain: 130.0;breast: 94.0;heart muscle: 109.2;liver: 130.8" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;CAPAN-2: 138.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA012107: AB_1856610, HPA063921: " "unprognostic (2.10e-1)" "unprognostic (2.62e-3)" "unprognostic (7.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (6.53e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "prognostic unfavourable (7.56e-5)" "unprognostic (7.18e-2)" "unprognostic (3.27e-1)" "unprognostic (4.73e-2)" "prognostic unfavourable (7.79e-5)" 245.0 21.3 59.8 11.4 32.7 5.5 94.0 12.7 83.9 5.3 10.8 63.6 0.1 21.4 3.7 7.0 13.4 1.7 18.3 109.2 61.5 43.4 5.0 130.8 32.2 23.1 65.1 23.6 12.7 6.1 7.7 1.5 5.3 34.5 24.4 10.1 4.5 24.9 3.7 2.4 3.4 6.1 4.6 130.0 4.2 5.9 12.2 35.4 1.4 2.0 6.9 5.4 3.7 5.0 2.0 5.3 0.2 3.3 2.9 5.1 2.1 30.4 28.0 59.8 40.9 199.5 115.1 12.2 3.2 72.1 7.8 41.8 24.1 138.2 12.8 2.6 7.6 54.4 32.9 116.8 6.9 4.3 13.6 7.2 17.8 48.2 38.6 10.0 7.8 62.6 35.4 30.4 53.6 14.8 20.0 39.2 3.1 47.6 11.3 12.0 20.7 8.1 5.3 22.1 40.2 34.2 34.1 3.7 14.4 6.4 30.5 62.7 34.2 21.6 5.9 0.7 9.3 0.7 6.7 11.0 5.8 19.8 14.3 31.3 5.0 0.0 1.5 0.0 3.0 3.3 5.1 1.3 1.2 1.6 5.3 2.0 1.0 2.9 0.2 2.9 0.0 3.0 0.0 2.1 59.8 32.7 12.7 27.9 61.5 43.4 65.1 23.6 34.5 35.4 SCD5 "ACOD4, FADS4, FLJ21032, HSCD5, SCD4" ENSG00000145284 "Stearoyl-CoA desaturase 5" Q86SK9 4 82629539-82798857 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 69.1;brain: 137.3;epididymis: 44.5;ovary: 42.7" "Cell line enhanced" "Detected in many" "BJ: 27.1;RPTEC TERT1: 35.8" "Group enriched" "Detected in all" 6 "glioma: 152.4;thyroid cancer: 38.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042380 Uncertain "HPA042380: AB_10794797" "unprognostic (3.23e-2)" "unprognostic (3.84e-2)" "unprognostic (2.86e-1)" "unprognostic (6.98e-2)" "unprognostic (1.58e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (3.82e-2)" "unprognostic (6.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "prognostic favourable (2.32e-5)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.88e-3)" "unprognostic (2.92e-2)" 3.0 69.1 61.2 2.7 48.6 2.5 3.0 33.5 137.3 5.9 3.0 50.4 1.8 3.0 6.7 44.5 3.7 9.3 5.1 3.5 49.6 43.4 15.4 2.3 7.5 2.3 58.2 36.3 42.7 18.1 2.2 6.9 4.4 42.0 6.9 3.0 6.3 5.6 12.4 1.7 4.8 3.7 6.2 57.1 3.0 4.3 14.8 43.4 1.2 16.4 0.0 3.0 3.8 2.0 0.9 1.3 3.0 1.2 2.0 7.2 1.8 4.4 2.8 14.5 7.4 8.0 5.2 0.3 27.1 13.4 11.9 9.2 0.3 0.7 8.8 9.5 5.6 7.9 4.2 3.0 15.0 1.7 1.9 0.4 3.5 0.4 1.2 3.9 2.9 4.1 12.2 2.4 2.1 19.0 0.6 1.1 6.2 1.7 16.0 0.9 1.1 1.9 13.7 8.6 6.9 35.8 4.4 8.1 4.6 4.5 0.4 2.6 0.6 2.0 23.3 12.8 7.5 4.8 7.3 2.5 1.0 0.9 6.2 4.1 3.6 3.0 1.2 0.4 7.2 0.5 4.6 0.5 1.7 4.3 0.5 0.9 1.5 5.1 2.0 2.0 0.9 1.3 0.4 1.8 61.2 48.6 33.5 41.2 49.6 43.4 58.2 36.3 42.0 43.4 SCLY SCL ENSG00000132330 "Selenocysteine lyase" Q96I15 2 238060889-238099413 "Enzymes, Predicted intracellular proteins" "Lyase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055760 Uncertain Approved "Golgi apparatus" 110000 "Golgi apparatus" "HPA055760: " "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (8.65e-5)" "unprognostic (8.96e-2)" "unprognostic (9.85e-3)" "unprognostic (1.14e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-2)" "unprognostic (8.38e-2)" "unprognostic (3.98e-3)" "unprognostic (1.03e-2)" "unprognostic (1.02e-3)" "unprognostic (3.73e-1)" "unprognostic (4.37e-2)" "unprognostic (2.50e-3)" "unprognostic (1.98e-1)" 4.1 3.8 6.0 6.3 7.4 5.3 3.6 10.2 7.4 4.3 6.3 11.1 5.7 9.8 8.4 8.3 4.5 4.6 5.4 6.5 7.3 6.8 9.9 24.1 4.0 6.5 9.6 4.7 6.3 22.7 5.2 5.1 2.6 6.6 5.0 4.3 6.4 4.5 5.6 5.1 2.8 9.6 5.1 9.4 5.6 3.9 15.3 6.1 8.9 8.1 6.3 5.3 4.6 4.0 5.0 5.7 6.9 5.6 4.2 8.1 4.3 5.7 9.8 6.2 16.6 5.1 3.4 12.6 5.9 2.9 6.2 7.6 6.4 4.7 9.6 1.7 3.4 8.4 24.4 12.4 5.9 10.9 21.9 11.1 13.1 22.0 9.5 9.2 9.6 3.8 6.2 11.6 13.4 11.5 19.3 2.8 6.3 8.6 9.1 17.0 20.1 8.1 10.7 12.0 9.5 5.9 2.0 7.1 15.2 6.4 10.3 10.4 3.3 13.6 5.0 9.4 6.1 12.5 12.4 6.8 6.2 4.8 5.8 18.7 7.4 2.0 5.3 6.9 4.7 4.3 3.7 5.0 5.7 8.1 5.7 3.5 4.3 4.2 0.9 4.2 5.6 1.2 5.3 4.3 6.0 7.4 10.2 7.4 7.3 6.8 9.6 4.7 6.6 6.1 SCP2 ENSG00000116171 "Sterol carrier protein 2" P22307 1 52927229-53051703 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 168.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027101, HPA027135, HPA027317" Supported Supported Peroxisomes 370000 Peroxisomes "HPA027101: AB_1856634, HPA027135: AB_1856633, HPA027317: AB_10610422" "unprognostic (7.51e-2)" "unprognostic (5.23e-2)" "prognostic favourable (7.05e-5)" "unprognostic (9.68e-2)" "unprognostic (1.53e-2)" "unprognostic (5.53e-2)" "unprognostic (1.87e-3)" "unprognostic (1.22e-2)" "unprognostic (1.62e-2)" "unprognostic (1.59e-1)" "unprognostic (4.53e-2)" "unprognostic (6.16e-2)" "prognostic favourable (7.85e-8)" "unprognostic (1.49e-2)" "unprognostic (1.09e-1)" "unprognostic (8.64e-2)" "unprognostic (1.13e-2)" 29.1 26.2 21.8 19.9 21.2 14.0 30.3 12.0 19.7 24.4 51.9 15.9 28.1 49.2 19.0 28.8 32.2 18.1 32.1 29.3 20.0 20.0 54.2 168.3 21.8 14.0 25.6 17.8 22.8 24.6 16.7 24.1 17.1 21.9 25.5 40.5 18.9 21.8 23.3 22.0 18.8 80.1 20.6 27.1 20.9 33.9 16.7 19.4 23.0 28.2 28.6 17.6 22.3 20.5 36.4 57.1 67.8 50.7 40.8 49.2 61.2 25.9 14.3 19.3 35.3 63.3 54.1 20.9 31.0 46.6 20.4 29.6 12.8 28.2 24.7 33.6 45.4 18.3 13.2 29.0 31.2 36.0 19.2 26.6 20.5 26.3 42.2 38.3 44.9 43.9 39.6 24.2 12.1 57.7 23.6 12.9 41.2 15.0 42.5 33.3 21.1 28.1 22.4 33.9 33.8 56.5 44.2 16.0 19.2 27.1 55.0 25.9 28.1 43.8 44.6 27.8 14.4 48.4 24.7 21.6 27.4 28.9 36.0 38.1 25.7 55.4 48.7 67.8 49.2 50.7 39.9 36.4 39.2 48.6 57.1 29.8 33.2 47.1 7.5 40.8 46.8 37.1 47.1 61.2 21.8 21.2 12.0 19.7 20.0 20.0 25.6 17.8 21.9 19.4 SCPEP1 RISC ENSG00000121064 "Serine carboxypeptidase 1" Q9HB40 17 56978105-57006768 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 113.9" "Cell line enhanced" "Detected in all" "ASC diff: 79.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 60.8" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039102, HPA057200" Enhanced Approved "Golgi apparatus" "Secreted to blood" "Golgi apparatus" "HPA039102: AB_10673605, HPA057200: " "unprognostic (5.83e-3)" "unprognostic (7.43e-3)" "unprognostic (4.47e-2)" "unprognostic (2.96e-1)" "unprognostic (9.26e-2)" "unprognostic (1.43e-2)" "prognostic unfavourable (1.96e-5)" "unprognostic (1.00e-3)" "unprognostic (1.68e-1)" "unprognostic (1.70e-1)" "unprognostic (3.56e-3)" "unprognostic (1.40e-1)" "unprognostic (3.25e-1)" "unprognostic (7.28e-2)" "unprognostic (8.89e-2)" "unprognostic (8.33e-2)" "unprognostic (1.68e-1)" 29.5 54.1 14.7 12.6 10.2 17.8 25.8 8.8 14.8 21.5 17.6 12.8 50.1 8.8 17.5 24.1 25.9 14.6 20.7 25.0 10.2 11.8 24.8 8.7 25.6 24.5 12.2 14.3 19.9 9.4 113.9 13.6 7.6 14.2 24.6 9.5 13.4 31.5 37.6 6.4 17.8 15.9 23.2 13.9 22.3 20.8 7.7 10.8 2.4 62.7 14.1 25.3 24.7 20.8 14.1 23.4 60.8 44.8 4.6 3.0 20.3 9.5 5.8 9.1 8.5 79.3 17.8 5.1 4.6 23.2 8.1 16.2 2.7 6.1 12.9 27.1 10.9 9.3 4.3 20.8 8.6 17.4 7.5 3.8 5.9 1.6 18.1 7.9 39.5 21.5 8.9 10.5 8.1 13.5 1.1 46.4 11.6 4.1 3.6 19.8 4.1 8.5 5.0 11.2 8.3 1.8 29.6 2.8 7.1 11.7 8.8 6.9 4.0 20.3 7.2 24.7 6.6 14.5 5.2 52.4 38.3 7.1 17.3 5.6 6.7 0.3 44.8 60.8 3.0 27.1 1.9 12.9 2.1 1.9 23.4 14.1 2.9 2.9 7.3 4.6 25.3 4.5 2.5 20.3 14.7 10.2 8.8 14.8 10.2 11.8 12.2 14.3 14.2 10.8 SCRN1 KIAA0193 ENSG00000136193 "Secernin 1" Q12765 7 29920103-29990289 "Enzymes, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.8" "Cell line enhanced" "Detected in many" "WM-115: 71.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024517 Enhanced Approved Cytosol 110000 Cytosol "HPA024517: AB_2184811" "prognostic unfavourable (8.32e-4)" "prognostic unfavourable (8.46e-4)" "unprognostic (1.45e-1)" "prognostic unfavourable (4.00e-5)" "unprognostic (1.87e-2)" "unprognostic (2.43e-1)" "unprognostic (1.13e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "prognostic unfavourable (7.27e-4)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "prognostic favourable (1.15e-5)" "unprognostic (2.57e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "prognostic unfavourable (2.60e-4)" 6.8 14.8 32.0 6.3 31.5 3.6 7.6 62.8 55.4 12.4 8.1 23.2 4.5 3.4 13.3 8.8 10.0 13.9 8.5 9.8 26.6 30.7 12.8 1.5 8.3 6.7 42.7 26.6 17.5 18.5 42.9 12.1 8.0 26.3 15.0 5.6 7.8 8.4 20.2 1.0 5.7 5.0 17.7 42.9 5.2 7.1 11.4 23.3 8.2 7.1 1.5 10.6 9.4 5.8 10.4 7.8 6.9 16.7 4.8 8.1 2.2 22.3 16.2 26.4 10.6 18.8 28.9 0.1 20.9 28.1 22.7 24.6 18.6 17.8 2.7 18.6 26.8 10.1 30.0 8.9 33.3 0.1 6.3 9.3 10.9 12.0 24.0 0.0 0.1 24.0 12.8 20.6 11.1 20.9 0.1 7.3 32.0 12.6 3.2 0.0 24.0 17.4 0.0 28.2 0.2 15.9 11.0 9.7 22.9 21.6 14.1 24.1 18.9 1.4 23.0 29.5 25.5 0.3 26.4 2.4 36.2 0.2 13.9 0.1 71.2 2.2 2.3 6.9 0.6 10.2 8.1 10.4 0.1 0.8 7.7 5.0 0.6 1.0 0.4 4.8 16.7 7.8 0.0 2.2 32.0 31.5 62.8 43.1 26.6 30.7 42.7 26.6 26.3 23.3 SCRN2 ENSG00000141295 "Secernin 2" Q96FV2 17 47837692-47841333 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022934, HPA023434" Enhanced Supported "Nucleoplasm,Golgi apparatus" 350000 Nucleoplasm "Golgi apparatus" "HPA022934: AB_1856638, HPA023434: AB_1856639" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (2.86e-1)" "unprognostic (6.14e-2)" "unprognostic (2.46e-2)" "unprognostic (1.73e-1)" "prognostic favourable (3.86e-4)" "unprognostic (4.63e-2)" "unprognostic (3.25e-2)" "unprognostic (5.77e-2)" "unprognostic (1.28e-3)" "unprognostic (8.72e-2)" "unprognostic (3.43e-2)" "unprognostic (5.28e-3)" "unprognostic (1.64e-1)" "unprognostic (1.20e-1)" "prognostic favourable (5.83e-4)" 43.4 10.3 8.3 14.2 14.1 6.7 20.8 17.7 13.1 10.6 17.3 11.2 23.6 25.1 11.4 18.1 8.9 15.4 13.3 17.9 8.6 8.9 29.3 17.4 8.3 8.7 8.1 9.6 11.8 25.3 11.4 14.5 7.8 10.5 13.6 6.1 14.8 20.1 19.2 20.0 10.9 20.1 9.7 7.3 15.0 9.8 4.0 10.9 8.5 18.1 9.0 11.0 10.7 10.0 16.9 19.2 25.9 13.4 16.5 22.1 10.8 11.9 19.0 5.3 5.1 15.5 12.0 16.1 6.0 12.3 9.3 9.5 14.2 14.3 6.6 12.2 3.1 6.5 1.7 10.6 3.2 15.8 13.1 6.7 13.9 12.3 5.5 3.1 5.4 11.5 8.0 5.7 4.4 10.4 2.2 7.5 12.7 10.8 10.6 5.5 2.6 7.6 14.2 4.0 26.7 7.4 5.4 4.1 17.1 3.4 7.3 8.0 16.4 6.3 4.8 8.5 9.1 2.3 2.8 31.2 4.0 3.1 23.1 5.6 1.9 12.3 12.8 25.9 16.9 13.4 16.3 16.9 14.0 16.4 16.3 15.6 22.1 12.2 3.2 16.5 6.5 19.2 13.9 10.8 8.3 14.1 17.7 13.1 8.6 8.9 8.1 9.6 10.5 10.9 SCRN3 FLJ23142 ENSG00000144306 "Secernin 3" Q0VDG4 2 174395730-174429575 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034689, HPA034690" Approved Approved Vesicles,Cytosol 9300 "Vesicles, Cytosol" "HPA034689: , HPA034690: AB_10670574" "unprognostic (5.39e-3)" "unprognostic (4.58e-2)" "unprognostic (2.06e-2)" "unprognostic (3.58e-1)" "unprognostic (1.91e-1)" "unprognostic (1.89e-1)" "unprognostic (9.89e-2)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (5.85e-2)" "unprognostic (8.81e-2)" "unprognostic (1.30e-1)" "unprognostic (6.62e-3)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (5.57e-2)" "unprognostic (1.57e-1)" 12.4 15.9 19.2 7.6 18.4 3.7 11.4 13.2 27.0 8.4 10.4 16.7 12.5 15.4 10.3 10.1 14.2 9.1 9.4 21.2 20.2 20.0 17.4 18.0 10.1 10.5 23.5 21.1 11.7 12.1 26.6 20.6 10.9 25.9 13.4 11.3 8.7 10.6 12.3 30.3 11.5 11.5 11.8 27.9 9.3 10.2 8.4 20.2 10.4 17.3 6.2 9.5 11.2 9.1 9.9 6.9 18.5 4.6 5.5 7.5 2.2 9.0 5.6 14.5 13.4 11.3 12.8 8.2 14.0 10.8 10.9 13.0 5.5 6.7 1.7 9.2 13.9 9.1 11.2 12.1 14.0 19.7 10.1 16.9 12.2 4.3 17.0 12.9 8.9 14.3 15.1 20.0 14.7 12.5 11.1 6.6 14.7 10.1 10.6 12.5 7.1 23.8 5.3 15.2 9.9 12.1 9.3 9.4 26.5 9.6 9.6 17.6 12.8 12.5 9.1 12.6 6.6 14.8 11.7 17.5 18.1 0.2 13.8 6.4 12.7 4.8 4.6 1.9 4.6 2.7 3.3 7.0 4.7 4.3 4.3 9.9 7.5 5.9 18.5 5.5 3.6 6.9 4.8 2.2 19.2 18.4 13.2 27.0 20.2 20.0 23.5 21.1 25.9 20.2 SCYL1 "GKLP, HT019, MGC78454, NKTL, NTKL, P105, TAPK, TEIF, TRAP" ENSG00000142186 "SCY1 like pseudokinase 1" Q96KG9 11 65525077-65538704 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015015 Uncertain Supported Cytosol Cytosol "HPA015015: AB_1856643" "unprognostic (5.56e-2)" "unprognostic (1.16e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-1)" "unprognostic (1.23e-2)" "unprognostic (7.87e-2)" "unprognostic (1.23e-2)" "unprognostic (5.06e-2)" "unprognostic (1.14e-1)" "unprognostic (7.23e-2)" "unprognostic (4.41e-1)" "unprognostic (4.29e-1)" "unprognostic (7.86e-3)" "unprognostic (6.49e-3)" "unprognostic (4.27e-1)" "unprognostic (8.29e-2)" "unprognostic (2.29e-3)" 24.1 35.5 24.1 20.2 24.4 22.8 49.4 24.6 47.3 25.0 21.6 19.0 27.8 22.5 26.9 30.0 24.1 26.7 21.4 35.8 25.1 21.1 24.1 61.4 22.4 22.9 21.7 23.9 34.1 40.7 27.0 24.3 30.7 19.6 24.7 14.3 24.9 34.0 30.3 51.2 23.6 19.8 23.0 17.1 24.7 24.4 31.4 20.6 18.0 27.3 20.2 20.2 24.9 24.1 10.7 15.5 27.9 13.7 11.1 14.7 12.1 19.8 17.1 13.8 19.1 25.3 22.1 18.9 24.7 33.6 29.5 23.1 24.6 12.0 14.3 25.1 32.0 18.2 14.5 18.5 10.3 16.8 18.6 16.8 18.8 28.2 36.0 11.0 24.3 30.6 18.4 25.3 18.9 19.3 17.5 20.3 18.3 43.2 14.7 25.4 13.3 23.9 15.0 10.7 26.2 18.1 17.8 12.8 13.6 15.2 33.7 26.8 33.4 14.0 19.0 23.5 15.8 38.0 14.5 28.1 19.5 14.9 27.2 9.2 16.4 1.9 13.7 17.6 14.7 13.2 11.8 10.0 13.8 14.6 15.5 10.7 11.2 10.5 27.9 11.1 8.5 11.3 9.5 12.1 24.1 24.4 24.6 47.3 25.1 21.1 21.7 23.9 19.6 20.6 SCYL2 "CVAK104, KIAA1360" ENSG00000136021 "SCY1 like pseudokinase 2" Q6P3W7 12 100267140-100341724 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021050 Approved "HPA021050: AB_1846175" "unprognostic (7.01e-3)" "unprognostic (3.04e-2)" "unprognostic (4.34e-3)" "unprognostic (4.01e-2)" "unprognostic (3.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.27e-2)" "unprognostic (8.19e-2)" "unprognostic (5.32e-2)" "unprognostic (1.31e-1)" "unprognostic (1.34e-2)" "unprognostic (1.93e-2)" "unprognostic (4.44e-1)" "unprognostic (2.72e-1)" "unprognostic (3.46e-1)" "unprognostic (1.60e-1)" "unprognostic (2.18e-1)" 22.7 20.3 19.6 17.5 16.8 19.8 18.3 21.0 20.2 16.9 23.5 13.9 19.5 20.9 18.9 23.7 26.2 16.2 17.3 20.2 13.7 15.2 26.1 35.1 21.2 15.9 12.6 15.7 19.0 19.4 28.1 30.3 31.3 16.2 19.8 28.6 13.3 22.0 17.8 24.6 17.9 23.2 18.5 14.8 19.0 20.8 17.4 11.5 31.7 17.4 16.1 20.3 28.0 21.4 4.4 8.1 13.3 8.1 10.8 7.5 4.7 17.9 13.8 22.5 18.6 14.4 15.3 21.6 18.5 20.1 16.9 14.4 13.2 9.2 11.3 8.9 21.9 15.4 17.5 13.0 20.3 17.5 11.9 36.0 9.5 9.6 12.8 16.7 35.4 11.3 20.6 19.0 22.1 21.1 18.9 9.6 18.0 13.6 14.0 14.6 14.5 15.9 11.1 16.6 10.8 15.5 28.6 14.3 13.1 21.4 21.6 17.2 31.6 13.3 20.9 14.7 8.6 13.8 11.9 11.4 15.1 13.8 7.4 12.0 16.8 13.3 6.1 11.7 5.3 8.1 6.8 4.4 5.7 5.0 8.1 3.4 6.3 6.5 8.6 10.8 6.5 2.6 7.5 4.7 19.6 16.8 21.0 20.2 13.7 15.2 12.6 15.7 16.2 11.5 SCYL3 "PACE-1, PACE1" ENSG00000000457 "SCY1 like pseudokinase 3" Q8IZE3 1 169849631-169894267 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005624 Approved Uncertain "Nuclear bodies,Microtubules" Microtubules "Nuclear bodies" "HPA005624: AB_1854916" "unprognostic (2.35e-1)" "unprognostic (1.25e-1)" "unprognostic (7.53e-2)" "unprognostic (8.36e-2)" "unprognostic (7.13e-2)" "unprognostic (2.72e-3)" "unprognostic (1.31e-1)" "unprognostic (2.12e-2)" "unprognostic (2.85e-2)" "unprognostic (7.17e-2)" "unprognostic (8.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.20e-3)" "unprognostic (3.54e-1)" "unprognostic (1.75e-1)" "unprognostic (4.60e-2)" "prognostic favourable (8.85e-4)" 10.8 11.4 8.5 15.4 10.6 5.0 15.8 10.5 11.9 12.1 14.6 11.0 14.6 10.7 12.6 14.0 14.4 10.6 11.0 7.8 7.3 6.5 12.1 18.0 11.8 13.7 9.3 7.8 13.0 12.8 22.7 14.4 15.8 9.5 13.2 13.9 12.3 15.5 13.8 14.6 14.1 14.9 13.0 7.3 12.6 11.3 9.1 8.9 17.2 13.3 9.5 16.0 16.0 12.7 8.3 13.6 12.3 4.3 11.8 10.5 5.9 3.9 5.1 8.0 5.5 10.3 7.5 9.2 6.2 8.1 7.3 6.9 4.7 7.7 8.2 4.6 6.4 9.3 4.7 5.5 6.5 15.0 4.4 5.6 5.7 3.0 7.3 8.1 7.4 7.2 5.5 5.1 7.0 6.8 9.0 10.9 6.9 3.0 6.6 6.3 6.4 2.5 6.1 4.4 9.7 7.7 7.2 6.0 8.7 4.9 16.4 9.7 9.1 7.6 5.1 5.2 3.5 6.2 5.0 14.6 12.9 9.8 4.0 6.1 5.7 12.3 3.7 9.7 8.0 3.9 10.5 8.3 10.4 8.7 6.0 7.3 9.2 7.5 8.2 11.8 4.3 13.6 9.5 5.9 8.5 10.6 10.5 11.9 7.3 6.5 9.3 7.8 9.5 8.9 SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218241-256700 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease mutation, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 100.1;skeletal muscle: 114.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034929, HPA041981, HPA064582" Enhanced Supported Nucleoli,Mitochondria 780000 Mitochondria Nucleoli "CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293" "prognostic unfavourable (6.00e-4)" "unprognostic (1.93e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "prognostic favourable (9.53e-8)" "unprognostic (1.11e-2)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (1.79e-1)" 17.6 31.4 15.3 11.5 20.3 10.6 12.8 18.8 29.0 10.2 29.4 17.3 10.0 44.3 11.3 12.1 15.3 12.6 14.8 100.1 15.8 14.5 36.5 55.4 10.7 11.7 19.6 19.3 14.5 14.7 23.2 9.5 9.2 29.7 10.7 24.6 14.5 17.3 12.0 114.0 11.5 39.9 16.5 13.2 13.9 21.2 14.6 14.8 15.7 12.5 39.6 12.5 13.2 11.1 28.3 31.9 29.1 29.2 27.1 48.9 32.4 18.4 29.9 12.3 20.1 21.2 15.9 33.4 14.2 18.1 24.5 25.0 32.4 25.1 22.8 45.0 16.2 23.9 21.7 29.0 14.5 48.6 19.9 11.6 82.6 42.0 13.1 14.4 15.1 15.8 18.7 18.3 9.7 26.5 18.6 19.0 11.5 28.2 19.1 39.0 4.2 37.9 24.7 17.9 44.2 52.2 24.5 13.6 7.8 67.0 43.3 17.6 26.3 18.3 19.2 18.2 17.9 10.8 11.7 20.2 8.6 16.8 17.6 20.9 11.5 17.8 24.4 29.1 36.4 29.2 32.1 28.3 34.8 35.1 31.9 24.5 34.5 31.7 5.9 27.1 24.1 20.5 48.9 32.4 15.3 20.3 18.8 29.0 15.8 14.5 19.6 19.3 29.7 14.8 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054170 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: , CAB068234: , CAB068235: , HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favourable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 17.8 25.6 19.8 16.6 21.7 17.0 26.4 18.0 29.1 13.9 30.8 12.3 15.1 34.0 14.2 15.7 19.8 13.6 15.1 86.9 18.2 16.4 51.0 75.1 16.8 24.6 20.1 18.9 10.5 30.7 20.0 11.3 15.6 16.7 13.0 31.5 11.7 15.9 19.5 96.2 13.2 31.4 21.3 16.5 17.2 21.7 18.7 15.7 14.2 15.5 52.2 18.0 15.4 17.1 22.2 45.9 48.5 48.7 18.9 26.7 25.0 25.5 25.4 14.5 18.5 28.2 28.1 16.5 22.4 28.8 51.4 46.5 35.7 30.8 35.1 28.0 30.2 30.2 57.7 44.7 58.0 20.6 47.3 31.6 26.4 27.4 34.6 49.4 23.6 28.8 29.5 44.4 75.3 36.3 26.4 40.7 35.7 21.1 32.8 28.2 12.0 51.1 23.6 27.9 43.5 47.3 14.5 27.3 15.0 30.4 38.1 63.9 22.3 27.9 18.0 19.8 22.3 36.3 29.5 17.0 20.9 35.9 30.3 75.3 21.8 16.6 38.4 37.4 18.3 48.7 18.3 22.2 21.2 19.5 45.9 18.3 19.3 19.5 48.5 18.9 42.2 21.5 26.7 25.0 19.8 21.7 18.0 29.1 18.2 16.4 20.1 18.9 16.7 15.7 SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300010-56320776 "Enzymes, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.5;lung: 34.0;skin 1: 35.9;tongue: 25.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 19.9;HaCaT: 9.9;hTCEpi: 16.4;T-47d: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 36 "memory B-cell: 9.1;naive B-cell: 2.5" "Lineage enriched" "Detected in single" 56 "B-cells: 9.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA025224 Enhanced "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favourable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" 0.3 0.2 2.0 2.0 1.9 0.0 7.4 0.9 6.2 8.1 5.9 0.2 0.0 1.7 0.2 0.0 27.5 0.2 1.5 0.2 0.6 1.2 0.2 0.2 34.0 0.3 1.4 2.9 0.2 0.3 0.0 0.5 0.0 10.6 0.3 3.0 0.2 9.2 0.0 0.3 35.9 16.9 0.2 0.4 0.2 12.9 0.5 0.2 0.0 0.2 25.8 21.1 1.0 11.5 9.1 0.0 0.0 0.0 0.0 0.1 0.1 3.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 9.9 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.4 0.0 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 7.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 1.9 0.9 6.2 0.6 1.2 1.4 2.9 10.6 0.2 SDS SDH ENSG00000135094 "Serine dehydratase" P20132 12 113392445-113426301 "Enzymes, Plasma proteins, Predicted intracellular proteins" Gluconeogenesis Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "liver: 276.9" "Cell line enhanced" "Detected in some" "HMC-1: 5.4;SK-BR-3: 3.3" "Cancer enriched" "Detected in all" 31 "liver cancer: 165.3" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 10 "myeloid DC: 12.8" "Lineage enriched" "Detected in single" 15 "dendritic cells: 12.8" "Low region specificity" "Detected in single" HPA039230 Uncertain Approved Mitochondria,Cytosol Cytosol Mitochondria "HPA039230: AB_10674281" "unprognostic (1.31e-1)" "prognostic favourable (5.24e-4)" "unprognostic (6.37e-3)" "unprognostic (6.94e-2)" "unprognostic (9.19e-3)" "unprognostic (2.65e-2)" "unprognostic (2.35e-2)" "unprognostic (8.85e-2)" "unprognostic (1.79e-1)" "unprognostic (2.55e-1)" "unprognostic (4.89e-2)" "unprognostic (3.20e-1)" "unprognostic (4.08e-3)" "unprognostic (2.12e-1)" "unprognostic (2.07e-2)" "unprognostic (4.35e-1)" "unprognostic (2.99e-2)" 0.9 0.9 2.2 1.4 5.9 0.5 0.4 0.6 2.1 0.5 0.9 0.8 0.0 0.7 0.4 0.2 0.2 0.2 1.4 0.2 1.7 2.5 0.2 276.9 0.6 0.6 4.2 0.7 0.3 0.4 0.1 0.0 1.0 2.8 0.3 0.8 1.3 0.3 0.2 0.2 0.2 0.7 0.3 1.3 0.5 0.9 0.3 0.8 0.1 0.3 0.0 0.3 0.8 0.0 0.0 12.8 0.6 0.8 0.2 0.0 0.3 0.0 0.4 0.2 1.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.2 0.4 2.3 0.0 0.4 0.0 0.0 0.0 0.5 0.5 1.3 0.6 0.6 0.1 0.8 5.4 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 1.4 0.1 0.4 0.8 0.9 0.0 0.8 0.1 0.2 0.5 0.1 0.1 1.6 3.3 0.7 1.2 1.7 0.6 0.0 0.9 1.1 0.3 0.7 0.4 0.2 1.1 0.8 0.3 0.1 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.6 0.2 0.1 1.3 0.0 0.3 2.2 5.9 0.6 1.6 1.7 2.5 4.2 0.7 2.8 0.8 SDSL "cSDH, SDS-RS1" ENSG00000139410 "Serine dehydratase like" Q96GA7 12 113422237-113438276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 53.2" "Cell line enhanced" "Detected in many" "HMC-1: 22.2;MCF7: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 6.5;intermediate monocyte: 7.1;myeloid DC: 13.2;plasmacytoid DC: 12.8" "Group enriched" "Detected in many" 8 "dendritic cells: 13.2;monocytes: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005740 Approved Approved Cytosol Cytosol "HPA005740: AB_10601486" "unprognostic (1.34e-1)" "unprognostic (8.33e-2)" "unprognostic (3.62e-2)" "unprognostic (3.54e-2)" "unprognostic (2.24e-2)" "unprognostic (6.17e-3)" "unprognostic (1.57e-1)" "unprognostic (6.46e-2)" "unprognostic (8.22e-2)" "unprognostic (2.00e-2)" "prognostic favourable (8.58e-4)" "unprognostic (2.93e-1)" "prognostic favourable (3.09e-5)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (7.33e-2)" 3.1 15.3 4.2 3.8 5.1 1.4 2.8 1.5 7.1 2.6 7.1 5.5 6.2 10.0 2.5 9.7 1.3 4.6 5.2 7.2 3.6 6.1 15.5 53.2 2.8 2.8 9.5 4.2 4.6 15.3 5.0 7.6 3.1 7.8 4.2 5.0 4.6 4.9 4.5 2.1 0.7 7.8 2.9 8.8 3.0 5.2 7.0 2.6 1.5 20.3 1.3 1.6 4.0 1.5 1.1 13.2 0.3 7.1 1.3 0.2 1.7 3.5 14.0 1.9 5.8 0.4 0.8 1.4 2.0 0.5 2.2 1.8 5.9 3.8 0.1 10.5 3.3 3.6 0.9 4.7 0.7 8.4 3.5 9.0 3.4 2.5 11.8 1.1 22.2 1.9 6.7 5.4 8.0 3.2 6.9 2.7 2.6 38.0 0.0 4.5 2.0 6.0 0.0 2.9 6.7 5.7 4.4 0.6 0.2 8.6 9.8 8.3 12.0 10.2 2.9 2.7 5.2 11.9 1.8 0.6 0.5 0.1 11.4 3.7 3.3 0.1 6.5 0.0 0.0 7.1 0.0 1.1 0.0 0.0 13.2 0.1 0.0 0.0 0.3 1.3 0.9 12.8 0.2 1.7 4.2 5.1 1.5 7.1 3.6 6.1 9.5 4.2 7.8 2.6 SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716716 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" 7400000 "Nuclear membrane" "Golgi apparatus" "HPA047533: " "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favourable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavourable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favourable (2.95e-4)" "unprognostic (7.89e-2)" 65.5 43.6 18.7 23.3 17.3 36.4 42.6 11.2 15.5 44.4 38.5 23.0 38.8 20.7 41.8 57.9 40.3 27.3 33.2 30.8 18.7 18.4 56.5 68.2 44.7 41.1 24.7 12.6 55.7 70.9 21.2 41.7 46.0 18.4 44.4 28.0 28.5 43.5 36.2 51.9 23.3 33.3 39.7 31.5 38.4 29.5 28.2 19.7 33.2 74.6 39.3 32.1 49.8 37.8 29.1 44.3 32.6 48.4 34.3 45.9 46.3 23.6 51.1 37.7 58.3 47.8 59.7 29.0 37.8 44.1 31.1 37.2 54.7 58.7 11.8 24.9 46.5 51.6 52.3 31.7 33.8 28.9 38.6 34.3 58.2 51.3 41.5 25.8 38.9 41.1 39.9 21.4 34.8 43.9 34.1 31.6 41.9 55.5 10.5 56.1 40.1 22.0 13.2 48.8 38.3 69.8 66.3 18.5 41.6 31.4 35.2 85.1 34.4 60.0 29.9 31.5 23.7 26.9 46.0 31.1 58.9 16.6 34.2 45.5 24.6 20.7 43.8 24.1 28.4 47.3 28.5 29.1 35.4 30.4 43.8 26.6 30.2 30.9 32.6 34.3 48.4 44.3 45.9 46.3 18.7 17.3 11.2 15.5 18.7 18.4 24.7 12.6 18.4 19.7 SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139477-59158836 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 132.6" "Cell line enhanced" "Detected in many" "HDLM-2: 58.2;Karpas-707: 62.8;RPMI-8226: 127.1;U-266/70: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" "Nuclear membrane" "Golgi apparatus" "HPA026816: AB_10602089, HPA047533: " "unprognostic (1.47e-2)" "unprognostic (2.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.44e-2)" "unprognostic (3.13e-3)" "unprognostic (4.48e-3)" "unprognostic (2.95e-1)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.80e-2)" "unprognostic (1.72e-1)" "unprognostic (6.25e-2)" "unprognostic (3.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" 5.9 18.4 30.1 18.6 29.7 11.3 16.0 14.9 25.2 12.2 18.7 24.4 27.8 27.5 9.1 58.0 10.7 9.2 11.1 7.2 27.7 33.9 19.0 66.8 13.0 22.0 41.8 21.3 7.0 96.8 14.6 46.6 8.1 27.1 48.8 16.4 10.0 132.6 34.1 4.3 7.9 21.1 6.6 51.3 23.6 28.4 6.4 25.3 7.3 35.9 8.6 23.4 18.9 5.9 33.6 50.0 10.6 17.6 17.3 34.4 32.6 8.6 10.4 5.7 8.8 3.5 0.6 7.3 7.9 6.7 9.7 5.9 7.3 4.7 19.9 12.4 4.7 9.3 8.9 5.9 5.6 58.2 12.2 6.4 7.3 22.4 10.6 21.0 9.7 2.0 14.1 6.0 16.2 3.2 7.3 62.8 3.4 10.2 8.6 8.4 5.7 6.4 7.9 5.6 127.1 6.3 7.3 26.6 10.5 4.7 19.1 26.6 8.6 15.5 2.5 11.8 4.9 4.1 9.4 64.0 47.1 19.5 11.7 14.3 14.4 10.6 13.1 9.4 25.9 15.5 33.1 33.6 27.3 25.2 13.5 17.4 14.3 19.5 2.0 17.3 17.6 50.0 34.4 32.6 30.1 29.7 14.9 25.2 27.7 33.9 41.8 21.3 27.1 25.3 SELENBP1 "hSBP, hSP56, LPSB" ENSG00000143416 "Selenium binding protein 1" Q13228 1 151364302-151372733 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein transport, Transport" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 112.3" "Cell line enhanced" "Detected in many" "ASC diff: 38.1;HEL: 28.3;HSkMC: 19.6;SK-BR-3: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "myeloid DC: 4.8" "Lineage enriched" "Detected in many" 4 "dendritic cells: 4.8" "Low region specificity" "Detected in all" "HPA005741, CAB008366, HPA011731" Enhanced Supported Nucleoli 57000000 Nucleoli "CAB008366: AB_592677, HPA005741: AB_1856662, HPA011731: AB_1856663" "unprognostic (1.51e-1)" "unprognostic (7.01e-2)" "unprognostic (8.52e-3)" "unprognostic (6.25e-3)" "unprognostic (6.28e-2)" "prognostic favourable (6.63e-4)" "unprognostic (1.08e-2)" "unprognostic (1.21e-2)" "unprognostic (3.78e-3)" "unprognostic (2.86e-1)" "unprognostic (1.46e-1)" "unprognostic (2.60e-1)" "unprognostic (2.67e-2)" "unprognostic (6.98e-2)" "unprognostic (1.95e-1)" "unprognostic (1.86e-2)" "unprognostic (6.86e-3)" 27.9 5.1 17.2 28.9 16.4 17.6 18.4 6.5 11.9 15.1 105.1 10.4 15.8 17.2 13.5 23.1 11.0 32.4 28.8 11.7 18.5 5.1 20.8 56.3 64.9 5.6 10.9 14.9 13.2 7.2 1.4 4.1 5.6 11.3 19.1 112.3 27.9 14.5 15.4 15.9 6.4 29.1 22.9 6.5 13.0 29.1 4.1 13.0 0.0 52.9 18.3 6.0 15.8 8.1 0.0 4.8 0.0 1.1 0.0 0.0 5.5 0.0 4.2 7.9 0.4 38.1 15.2 2.0 1.5 0.7 0.8 1.6 4.3 1.3 0.0 7.3 2.6 0.0 0.0 0.1 0.6 0.0 3.6 28.3 14.2 6.8 8.0 0.0 0.0 19.6 0.2 1.3 0.0 4.8 2.8 0.0 2.0 3.1 0.0 0.0 6.3 8.0 0.0 0.4 0.1 1.7 0.0 0.1 0.1 0.0 68.0 0.0 11.7 0.4 0.4 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.5 17.2 16.4 6.5 11.9 18.5 5.1 10.9 14.9 11.3 13.0 SELENOI "EPT1, KIAA1724, SELI, SEPI" ENSG00000138018 "Selenoprotein I" Q9C0D9 2 26308547-26395891 "Enzymes, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064125 Approved "HPA064125: " "unprognostic (6.29e-2)" "unprognostic (7.46e-2)" "unprognostic (1.38e-3)" "unprognostic (3.05e-3)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "unprognostic (7.44e-3)" "unprognostic (5.00e-3)" "unprognostic (7.79e-2)" "unprognostic (2.55e-2)" "unprognostic (6.65e-2)" "unprognostic (9.40e-2)" "unprognostic (1.52e-2)" "unprognostic (2.95e-1)" "unprognostic (1.76e-1)" "unprognostic (9.87e-3)" "unprognostic (1.42e-2)" 5.5 8.8 10.3 7.0 20.6 13.3 10.8 21.4 22.5 7.1 10.7 14.1 5.0 15.3 5.8 7.6 15.7 5.0 5.6 6.1 14.7 11.3 10.6 28.6 6.7 6.9 9.7 9.4 5.9 11.3 27.2 11.7 8.5 14.9 8.5 11.5 9.2 9.5 6.2 10.1 22.5 22.1 5.2 15.6 6.3 9.1 5.8 11.0 8.0 9.4 9.4 9.1 7.1 9.9 5.4 3.0 0.6 2.5 2.1 5.0 1.0 19.2 11.9 9.9 9.9 6.2 5.0 15.1 9.4 4.3 4.8 4.9 25.1 12.4 22.5 11.6 4.4 15.9 15.2 8.3 7.0 6.2 7.2 14.2 8.6 14.7 5.9 18.8 4.7 3.9 7.5 10.5 10.5 4.3 16.0 7.8 6.3 8.4 11.2 9.4 12.7 8.2 10.2 23.3 11.4 9.3 14.9 21.7 9.2 8.0 17.0 7.5 8.1 5.6 7.0 8.2 10.6 10.7 14.5 10.7 26.5 30.8 8.4 11.7 7.3 0.1 1.7 0.0 2.2 2.5 2.3 5.4 2.3 2.9 1.7 2.6 3.0 5.0 0.6 2.1 2.1 3.0 4.1 1.0 10.3 20.6 21.4 22.4 14.7 11.3 9.7 9.4 14.9 11.0 SELENOT SELT ENSG00000198843 "Selenoprotein T" P62341 3 150602875-150630445 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039780 Approved "HPA039780: AB_10805594" "unprognostic (1.13e-1)" "unprognostic (4.03e-2)" "unprognostic (2.78e-1)" "unprognostic (1.92e-1)" "unprognostic (3.31e-1)" "unprognostic (1.34e-2)" "unprognostic (2.65e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "unprognostic (5.79e-3)" "unprognostic (6.30e-3)" "unprognostic (1.99e-1)" "unprognostic (3.08e-3)" "unprognostic (4.91e-2)" "unprognostic (4.08e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" 29.7 52.6 39.9 32.1 44.1 54.5 31.0 33.9 48.2 29.9 29.7 37.7 26.7 29.7 29.2 41.8 30.3 31.2 23.5 32.7 41.6 47.4 47.0 52.5 31.1 44.5 41.3 28.2 27.7 34.2 30.6 46.6 50.8 48.0 31.8 36.7 30.2 31.5 33.0 30.5 20.0 38.5 33.4 50.0 49.8 28.5 23.6 31.9 32.3 45.7 23.0 43.2 34.3 23.1 32.1 34.0 54.5 43.2 26.5 42.3 71.0 47.9 19.9 12.9 11.5 19.9 19.5 24.4 38.2 28.3 26.5 18.1 31.5 28.3 27.2 39.1 28.3 16.6 20.0 23.9 40.8 22.7 16.7 28.3 12.2 14.7 21.8 16.6 21.5 16.8 19.2 23.6 20.6 28.6 6.5 80.3 38.6 29.5 22.0 9.6 13.8 21.4 15.9 16.2 45.3 22.9 28.8 13.8 8.5 22.9 14.4 15.1 27.5 19.9 26.8 14.4 9.0 25.9 35.1 56.3 28.8 37.6 19.6 30.3 12.2 41.9 43.2 36.4 38.5 35.0 42.3 32.1 32.0 35.2 34.0 26.7 25.3 32.0 54.5 26.5 37.7 24.1 33.5 71.0 39.9 44.1 33.9 48.2 41.6 47.4 41.3 28.2 48.0 31.9 SENP1 ENSG00000079387 "SUMO1/sentrin specific peptidase 1" Q9P0U3 12 48042898-48106308 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 60.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011765, HPA046491" Supported "Nucleoplasm,Focal adhesion sites" Nucleoplasm "Focal adhesion sites" "HPA011765: AB_1079907, HPA046491: " "unprognostic (2.66e-2)" "unprognostic (6.51e-2)" "unprognostic (3.14e-1)" "unprognostic (5.69e-2)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "prognostic unfavourable (7.72e-5)" "unprognostic (6.48e-2)" "unprognostic (2.44e-3)" "unprognostic (8.20e-3)" "unprognostic (2.57e-1)" "unprognostic (2.23e-1)" "prognostic unfavourable (8.37e-4)" "unprognostic (7.61e-2)" "unprognostic (3.02e-1)" "unprognostic (1.01e-1)" "unprognostic (1.28e-1)" 5.7 3.3 3.0 9.0 4.0 8.4 5.2 5.3 3.2 5.5 4.9 3.8 3.5 3.4 6.2 4.3 5.7 5.2 3.8 3.6 2.7 3.3 3.8 3.9 4.3 7.3 3.0 2.3 6.2 4.4 6.1 11.4 8.1 3.0 4.4 4.7 5.1 20.0 4.7 6.8 6.6 4.5 5.8 4.3 6.4 4.5 60.2 3.6 15.0 5.2 4.8 8.3 5.7 6.3 5.3 3.8 7.1 2.6 3.8 5.5 2.3 7.0 9.1 11.3 8.5 3.4 5.0 8.4 7.6 8.5 13.1 10.6 11.1 11.4 19.2 6.6 6.9 6.9 14.0 6.7 13.3 17.4 6.3 16.8 8.8 5.3 5.6 15.6 11.4 4.1 5.5 11.7 10.5 6.8 14.7 9.1 6.8 5.6 19.5 5.0 10.3 6.9 18.4 12.0 9.4 3.6 8.6 11.9 8.2 11.0 6.7 4.5 10.6 7.5 6.2 11.1 9.9 6.5 8.0 9.5 15.3 18.7 6.8 36.3 5.0 2.0 1.8 7.1 4.3 2.6 5.5 2.4 4.2 3.9 3.3 5.3 3.6 4.1 3.8 3.8 2.0 3.8 5.0 2.3 3.0 4.0 5.3 3.2 2.7 3.3 3.0 2.3 3.0 3.6 SENP2 "AXAM2, DKFZp762A2316, KIAA1331, SMT3IP2" ENSG00000163904 "SUMO1/sentrin/SMT3 specific peptidase 2" Q9HC62 3 185582496-185633551 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029247, HPA029248" Approved Supported Cytosol Cytosol "HPA029247: AB_10599305, HPA029248: AB_10601855" "unprognostic (4.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.80e-2)" "prognostic unfavourable (7.98e-5)" "unprognostic (7.85e-2)" "unprognostic (2.90e-2)" "unprognostic (4.41e-3)" "unprognostic (1.45e-1)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (1.85e-1)" "unprognostic (8.41e-3)" "unprognostic (5.12e-2)" "unprognostic (6.92e-2)" "unprognostic (1.60e-1)" "unprognostic (1.92e-1)" "unprognostic (1.56e-1)" 10.3 10.1 16.0 7.6 19.8 13.8 11.6 18.8 20.2 8.7 8.8 13.8 7.8 9.2 9.5 15.4 9.3 9.7 7.0 10.9 15.2 15.1 11.3 14.2 9.5 8.6 14.6 12.0 16.0 9.1 15.6 16.7 13.4 13.9 9.7 9.6 9.1 11.0 10.3 24.6 13.9 8.5 9.2 12.9 9.2 9.4 34.9 17.1 11.0 11.2 7.3 8.9 8.5 9.3 4.2 4.4 7.8 3.2 5.1 3.8 1.9 15.2 3.1 7.6 8.6 13.7 9.3 9.9 7.2 8.1 9.0 9.6 11.6 4.9 8.2 13.5 6.4 8.1 15.8 5.8 13.3 6.1 7.5 5.6 6.4 6.9 7.3 8.2 3.7 5.7 8.7 5.1 6.2 6.2 6.6 11.8 7.7 7.6 6.9 9.1 28.1 5.3 8.2 10.4 13.7 4.9 5.1 7.9 8.8 5.9 13.2 11.0 18.1 11.0 3.9 6.0 6.5 10.9 11.2 13.6 16.2 15.2 9.8 8.8 8.1 7.2 3.0 5.4 3.7 2.8 3.8 3.0 3.1 3.0 2.2 4.2 3.7 3.6 7.8 5.1 3.2 4.4 2.7 1.9 16.0 19.8 18.8 20.2 15.2 15.1 14.6 12.0 13.9 17.1 SENP3 "DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3, Ulp1" ENSG00000161956 "SUMO1/sentrin/SMT3 specific peptidase 3" Q9H4L4 17 7561875-7571969 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA060290 Supported Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA060290: " "unprognostic (5.68e-2)" "unprognostic (2.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.01e-1)" "unprognostic (3.34e-1)" "unprognostic (3.48e-1)" "unprognostic (1.30e-3)" "unprognostic (2.82e-1)" "unprognostic (7.37e-2)" "unprognostic (3.72e-2)" "prognostic favourable (6.22e-5)" "unprognostic (2.71e-2)" "unprognostic (1.96e-1)" "unprognostic (1.42e-1)" "unprognostic (1.37e-1)" "unprognostic (8.21e-2)" "unprognostic (2.56e-2)" 16.3 16.0 22.3 20.9 23.4 16.6 18.0 29.2 38.4 15.9 22.5 18.4 16.8 16.2 18.6 22.7 18.6 19.9 17.0 26.1 21.0 19.2 17.5 15.1 18.7 18.8 20.0 23.3 19.6 17.8 29.5 17.3 23.6 17.2 16.0 20.5 17.3 18.6 21.9 22.0 20.8 17.6 23.1 15.3 18.9 17.2 28.8 16.4 18.9 19.0 14.2 23.4 16.8 32.8 0.8 0.7 1.1 0.7 1.1 1.7 0.3 26.2 31.8 18.9 29.2 21.4 15.7 19.7 19.3 19.8 33.6 31.6 19.0 11.5 31.4 19.1 25.3 25.3 40.6 30.1 28.3 22.1 37.1 16.3 27.0 19.4 29.0 15.0 20.8 20.1 30.8 38.3 37.6 26.9 20.8 8.8 25.9 17.6 36.3 11.4 23.4 19.4 33.3 17.7 18.1 22.4 15.4 18.9 24.4 19.3 18.7 20.5 15.7 9.8 14.1 19.3 16.8 18.3 41.3 13.0 13.5 19.9 19.5 15.9 28.5 0.1 0.7 0.2 0.4 0.4 0.1 0.4 0.2 1.3 0.1 0.8 1.7 0.5 1.1 1.1 0.1 0.7 0.3 0.3 22.3 23.4 29.2 38.4 21.0 19.2 20.0 23.3 17.2 16.4 SENP5 MGC27076 ENSG00000119231 "SUMO1/sentrin specific peptidase 5" Q96HI0 3 196867856-196934714 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006684 Supported "Nucleoli,Plasma membrane" Nucleoli "Plasma membrane" "HPA006684: " "unprognostic (4.07e-2)" "unprognostic (4.91e-3)" "unprognostic (7.63e-2)" "prognostic unfavourable (4.04e-4)" "unprognostic (4.13e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (4.15e-4)" "unprognostic (2.95e-1)" "unprognostic (2.20e-1)" "unprognostic (2.88e-1)" "unprognostic (2.89e-1)" "unprognostic (9.57e-3)" "prognostic unfavourable (2.14e-5)" "unprognostic (2.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.62e-2)" "unprognostic (6.71e-2)" 13.8 13.5 20.0 15.3 20.0 25.7 16.1 28.3 23.8 15.0 15.1 16.1 14.5 11.3 14.6 16.2 16.3 12.9 14.4 15.9 18.9 21.7 13.6 19.5 15.2 15.9 19.4 18.4 17.5 15.7 19.8 21.5 17.8 23.5 15.1 14.0 12.0 13.2 15.9 17.8 16.4 13.0 16.8 18.2 17.1 14.0 36.6 16.4 19.3 14.1 9.2 21.1 14.9 20.1 8.9 7.8 15.8 8.7 7.6 8.9 4.2 13.1 6.0 9.6 8.6 8.1 9.8 7.6 8.4 9.0 9.1 14.7 10.4 5.2 12.3 23.4 9.2 9.1 9.9 4.5 14.9 6.6 6.5 16.7 8.9 7.3 9.5 13.7 7.9 8.4 12.1 9.3 9.9 8.9 11.0 19.1 10.6 11.3 12.9 8.1 7.4 11.9 8.3 7.7 8.3 4.5 7.5 6.0 8.0 9.4 10.6 10.3 17.8 10.5 10.0 8.9 9.2 12.2 17.1 20.4 35.7 26.5 12.0 11.1 10.1 15.8 7.6 7.1 8.9 8.1 8.1 8.9 8.6 8.8 5.0 8.5 8.0 8.6 14.9 7.6 8.7 7.8 6.9 4.2 20.0 20.0 28.3 23.8 18.9 21.7 19.4 18.4 23.5 16.4 SENP6 "KIAA0797, SUSP1" ENSG00000112701 "SUMO1/sentrin specific peptidase 6" Q9GZR1 6 75601509-75718278 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024376 Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA024376: AB_1856678" "unprognostic (9.86e-2)" "unprognostic (1.20e-2)" "unprognostic (4.84e-2)" "unprognostic (1.87e-2)" "unprognostic (6.38e-3)" "unprognostic (7.33e-2)" "unprognostic (1.13e-2)" "unprognostic (2.97e-1)" "unprognostic (3.93e-2)" "unprognostic (5.32e-3)" "unprognostic (7.81e-2)" "unprognostic (9.24e-2)" "prognostic unfavourable (6.09e-4)" "unprognostic (1.78e-1)" "unprognostic (1.74e-1)" "prognostic unfavourable (2.83e-5)" "unprognostic (1.72e-1)" 25.9 20.0 24.3 21.8 24.5 27.1 25.9 35.0 24.3 32.5 27.7 23.5 24.9 16.8 37.7 21.2 21.0 27.4 21.5 20.0 22.8 19.8 24.1 22.5 22.5 21.1 29.6 20.3 38.7 21.8 40.1 44.2 26.8 27.0 27.7 21.8 23.0 20.4 25.7 27.8 22.0 24.1 43.0 27.2 24.7 21.3 26.1 28.6 28.5 34.8 15.8 23.9 27.1 34.0 9.9 10.9 19.4 13.1 9.8 11.2 5.5 10.7 11.3 25.7 18.4 20.0 26.7 19.1 19.4 21.7 16.4 20.6 15.5 10.4 18.3 18.4 22.4 13.8 24.1 12.9 25.5 26.8 20.8 27.7 13.6 14.4 27.8 24.0 20.4 20.6 21.6 15.4 34.4 27.1 33.4 20.3 20.1 13.1 9.5 13.0 15.6 9.6 18.0 13.6 26.6 17.6 16.1 22.5 23.2 16.6 14.7 16.8 13.2 23.0 22.6 14.7 16.1 7.5 20.0 23.3 23.1 14.6 7.4 23.0 15.5 5.2 7.4 19.4 7.7 7.9 11.2 9.3 7.8 10.2 8.7 9.9 11.2 9.9 14.7 9.8 13.1 10.9 6.5 5.5 24.3 24.5 35.0 24.3 22.8 19.8 29.6 20.3 27.0 28.6 SENP7 ENSG00000138468 "SUMO1/sentrin specific peptidase 7" Q9BQF6 3 101324205-101513241 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027259 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA027259: AB_1856679" "unprognostic (1.50e-1)" "unprognostic (6.12e-2)" "unprognostic (2.78e-2)" "unprognostic (7.31e-2)" "unprognostic (2.44e-2)" "prognostic favourable (4.23e-4)" "unprognostic (1.38e-3)" "unprognostic (9.25e-3)" "unprognostic (8.80e-2)" "unprognostic (2.24e-1)" "unprognostic (7.77e-3)" "unprognostic (1.94e-1)" "unprognostic (9.85e-2)" "unprognostic (8.08e-3)" "unprognostic (3.27e-1)" "unprognostic (9.03e-2)" "unprognostic (2.23e-2)" 17.0 9.0 11.0 19.1 14.5 19.5 16.5 35.5 19.5 21.7 13.1 11.8 8.2 6.4 24.3 15.2 11.9 18.6 12.8 10.0 13.2 9.1 10.5 7.7 11.5 19.0 12.9 10.8 27.9 15.9 22.4 24.4 17.0 18.7 15.1 10.0 9.2 10.2 11.1 11.1 18.6 13.8 16.0 17.3 14.1 13.6 7.9 16.8 32.1 16.0 9.4 15.4 17.2 14.0 6.8 3.2 24.5 4.1 6.2 7.6 3.8 6.9 4.7 23.4 12.9 4.5 6.9 4.3 4.1 3.0 6.8 8.4 3.1 6.5 5.4 6.3 3.9 7.1 7.3 3.7 13.7 10.0 2.1 9.8 3.7 4.2 3.7 5.6 9.6 5.2 6.8 3.4 7.8 9.7 8.0 13.9 6.4 4.6 10.3 6.6 4.8 5.1 11.6 6.2 4.9 8.1 4.1 9.1 7.0 3.8 3.8 5.1 6.3 7.6 7.9 9.5 5.8 3.1 4.0 9.9 5.9 12.7 3.3 7.5 7.7 24.5 4.1 3.8 4.2 3.6 5.2 4.2 5.6 4.2 3.2 6.8 7.6 5.1 12.6 6.2 3.8 2.8 4.5 3.8 11.0 14.5 35.5 19.5 13.2 9.1 12.9 10.8 18.7 16.8 SENP8 "DEN1, HsT17512, NEDP1, PRSC2" ENSG00000166192 "SUMO/sentrin peptidase family member, NEDD8 specific" Q96LD8 15 72114258-72143688 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036273 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA036273: AB_10669985" "unprognostic (1.83e-2)" "unprognostic (1.78e-1)" "unprognostic (9.85e-4)" "unprognostic (5.43e-2)" "unprognostic (1.49e-1)" "unprognostic (6.09e-3)" "unprognostic (3.06e-2)" "unprognostic (4.35e-2)" "unprognostic (1.06e-1)" "unprognostic (2.04e-1)" "unprognostic (3.11e-2)" "unprognostic (1.19e-1)" "unprognostic (8.46e-12)" "unprognostic (1.24e-1)" "unprognostic (1.12e-1)" "unprognostic (1.85e-2)" "unprognostic (1.54e-2)" 2.5 4.8 6.4 3.4 8.1 5.0 4.4 5.7 8.0 4.0 4.0 3.9 6.4 3.8 3.9 6.7 4.8 5.1 4.2 7.7 7.3 6.9 9.3 5.0 3.3 3.1 6.2 7.7 5.3 6.2 3.9 12.7 3.7 8.0 5.9 4.3 4.2 5.6 6.6 11.0 3.5 3.3 4.2 5.0 3.1 4.3 26.5 4.3 2.2 12.0 4.5 2.7 4.9 3.0 3.0 5.7 2.1 5.6 7.1 3.7 2.1 1.9 3.2 6.3 5.0 7.6 9.2 3.5 5.0 3.1 3.0 2.8 2.7 4.5 1.9 7.4 3.2 4.5 9.6 7.7 4.4 2.1 5.3 3.0 4.5 2.2 5.3 3.6 1.7 4.5 7.8 1.9 8.4 2.8 4.6 3.6 7.1 4.9 3.6 4.7 5.0 3.3 2.4 5.4 4.0 7.9 3.4 7.7 2.5 5.3 4.4 5.2 6.7 2.7 2.9 6.1 2.2 10.1 2.5 3.0 3.6 2.3 2.9 5.0 4.3 2.1 1.9 1.4 1.6 3.9 2.3 3.0 2.8 2.5 5.7 1.4 3.1 3.7 0.7 7.1 5.6 1.7 2.1 2.1 6.4 8.1 5.7 8.0 7.3 6.9 6.2 7.7 8.0 4.3 SEPHS1 "SPS, SPS1" ENSG00000086475 "Selenophosphate synthetase 1" P49903 10 13317424-13348298 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037645, HPA062118" Enhanced Uncertain Nucleoplasm Nucleoplasm "HPA037645: AB_10671631, HPA062118: " "unprognostic (8.18e-3)" "unprognostic (1.79e-1)" "unprognostic (1.06e-3)" "unprognostic (2.07e-1)" "unprognostic (3.50e-2)" "unprognostic (2.99e-2)" "prognostic unfavourable (2.16e-7)" "unprognostic (2.66e-2)" "unprognostic (1.43e-1)" "unprognostic (2.61e-2)" "prognostic favourable (3.12e-4)" "unprognostic (1.09e-1)" "unprognostic (1.38e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (5.11e-2)" 15.1 21.9 19.8 11.4 18.0 11.5 33.2 17.3 16.2 14.4 16.0 14.6 10.4 11.9 17.5 20.2 15.4 19.1 15.1 16.1 18.3 15.4 30.5 39.1 20.0 24.3 16.3 11.2 19.8 37.3 23.2 16.6 14.2 17.3 14.4 17.6 15.1 20.6 14.0 20.5 11.8 13.0 17.7 16.6 17.9 15.1 13.7 16.1 44.7 29.8 22.2 17.2 14.1 17.0 8.1 13.2 8.7 19.6 12.7 10.9 6.6 28.0 20.5 42.0 40.4 14.0 10.7 19.8 12.5 9.7 26.8 22.8 23.2 26.5 27.4 15.6 14.6 18.0 44.5 20.7 28.1 41.2 18.4 15.0 15.3 29.4 14.5 20.2 9.5 9.3 14.9 15.6 9.2 21.6 19.7 22.4 19.0 37.2 49.9 8.6 69.4 9.3 39.0 20.5 16.4 14.5 11.4 14.9 27.8 38.4 17.0 17.2 21.5 21.5 14.4 11.9 22.8 15.5 26.1 16.5 30.5 50.8 9.6 15.1 9.5 8.7 9.7 7.1 7.1 14.5 8.6 8.1 7.3 8.0 11.6 6.3 9.4 8.7 1.5 12.7 19.6 13.2 10.9 6.6 19.8 18.0 17.3 16.2 18.3 15.4 16.3 11.2 17.3 16.1 SEPHS2 "SPS2, SPS2b" ENSG00000179918 "Selenophosphate synthetase 2" Q99611 16 30443631-30446181 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 52.8;liver: 111.2" "Cell line enhanced" "Detected in all" "HMC-1: 94.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047931 Approved Approved Nucleoplasm Nucleoplasm "HPA047931: " "unprognostic (5.33e-2)" "unprognostic (2.02e-1)" "unprognostic (1.92e-2)" "unprognostic (9.85e-2)" "unprognostic (2.67e-2)" "unprognostic (6.29e-2)" "unprognostic (5.67e-2)" "unprognostic (7.69e-3)" "unprognostic (2.38e-1)" "unprognostic (9.86e-2)" "unprognostic (9.66e-3)" "unprognostic (1.49e-1)" "prognostic favourable (4.35e-8)" "unprognostic (2.24e-2)" "unprognostic (1.35e-1)" "unprognostic (3.25e-2)" "unprognostic (3.62e-2)" 9.0 9.0 4.9 6.9 6.4 4.0 6.7 6.3 8.4 5.3 25.6 5.2 5.5 26.6 7.6 6.1 6.0 6.1 12.6 5.3 5.2 5.1 32.8 111.2 5.8 7.6 5.5 3.8 5.2 10.0 7.3 6.4 7.5 7.7 6.6 13.1 6.2 10.6 4.7 11.1 5.5 52.8 4.9 4.4 10.5 12.1 3.0 4.6 14.1 11.9 6.4 9.5 8.1 4.4 14.6 15.3 20.5 13.7 23.2 18.9 8.9 14.5 13.2 4.7 16.2 14.4 9.2 12.3 10.1 12.5 9.9 12.3 8.1 11.1 20.9 15.6 10.6 8.1 8.6 9.2 10.1 13.3 26.6 20.9 7.1 38.2 18.2 11.6 94.5 11.7 19.7 9.3 17.4 9.1 16.8 13.6 8.8 21.5 17.4 23.9 11.6 9.9 17.0 8.2 16.0 12.2 13.1 9.9 8.5 8.6 25.3 32.7 22.2 38.7 7.6 10.4 7.4 10.0 6.0 11.8 18.8 10.9 9.0 21.6 11.5 6.1 12.9 20.5 11.2 11.2 17.1 12.4 15.9 16.1 15.3 14.6 18.9 12.9 12.9 23.2 13.7 10.9 15.1 8.9 4.9 6.4 6.3 8.4 5.2 5.1 5.5 3.8 7.7 4.6 SEPSECS "SLA, SLA/LP" ENSG00000109618 "Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase" Q9HD40 4 25120014-25160442 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "RNA-binding, Transferase, tRNA-binding" "Disease mutation, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 34.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070409 Approved Vesicles Vesicles "HPA070409: " "unprognostic (1.83e-1)" "unprognostic (4.09e-2)" "unprognostic (6.37e-3)" "unprognostic (5.86e-2)" "unprognostic (9.63e-2)" "unprognostic (4.61e-3)" "unprognostic (1.82e-3)" "unprognostic (6.33e-2)" "unprognostic (1.24e-1)" "unprognostic (3.34e-1)" "unprognostic (2.52e-1)" "unprognostic (3.56e-2)" "unprognostic (4.45e-3)" "unprognostic (4.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (2.13e-3)" 7.0 6.1 3.8 8.5 6.4 11.8 7.4 5.4 6.0 5.3 13.5 7.8 8.9 11.8 6.7 9.6 5.3 6.5 8.9 5.6 4.8 3.6 10.5 34.2 9.4 9.7 7.2 4.9 8.5 11.3 7.3 5.1 4.4 5.4 4.7 7.8 5.2 6.2 9.2 5.5 10.9 15.3 3.7 7.0 7.5 7.4 8.9 6.8 12.3 7.7 4.8 8.0 6.8 5.5 5.7 5.9 3.2 4.0 3.4 5.5 2.2 2.9 1.6 6.3 3.3 5.7 8.0 5.5 3.1 4.1 3.4 3.4 1.3 7.3 5.4 3.0 3.5 3.6 4.9 3.6 3.8 2.7 1.6 6.7 5.6 2.6 6.4 5.9 8.8 7.5 5.8 2.5 5.7 3.6 10.5 5.5 2.7 1.7 9.4 16.5 2.9 6.2 4.8 7.4 4.8 4.7 3.1 4.7 4.4 2.8 2.2 5.2 4.2 5.7 3.7 5.2 2.7 1.7 2.9 8.7 9.7 6.0 3.2 9.7 3.2 2.4 4.0 2.2 3.6 3.4 3.5 3.4 4.5 4.9 3.4 5.7 4.6 5.5 3.2 3.4 2.4 5.9 2.6 2.2 3.8 6.4 5.4 6.0 4.8 3.6 7.2 4.9 5.4 6.8 SESN1 "PA26, SEST1" ENSG00000080546 "Sestrin 1" Q9Y6P5 6 108986437-109094819 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 6 "B-cells: 21.0;NK-cells: 21.8;T-cells: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073659 Supported "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA073659: " "unprognostic (2.22e-1)" "unprognostic (5.97e-2)" "unprognostic (1.02e-1)" "unprognostic (3.52e-2)" "unprognostic (1.17e-1)" "prognostic favourable (6.47e-5)" "unprognostic (2.68e-1)" "unprognostic (6.91e-2)" "unprognostic (1.01e-1)" "unprognostic (8.33e-2)" "unprognostic (1.83e-3)" "prognostic favourable (2.07e-4)" "unprognostic (3.54e-2)" "unprognostic (1.65e-1)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (7.95e-2)" 23.5 14.2 14.5 11.0 23.7 22.7 39.3 21.2 18.9 13.2 16.9 10.2 17.3 10.3 17.1 14.4 11.9 15.2 10.0 32.4 13.0 11.3 8.8 14.1 17.5 54.1 12.2 14.6 33.0 16.1 18.1 25.6 26.8 13.0 15.2 12.8 9.5 10.0 17.2 69.2 19.7 18.6 17.9 13.7 19.3 14.9 20.8 13.6 9.6 18.2 15.4 16.4 16.1 15.3 21.0 2.1 3.9 3.0 21.8 30.6 7.8 1.5 2.5 11.6 5.4 14.8 18.9 36.4 6.1 7.0 2.1 4.1 4.7 1.6 12.7 5.1 4.5 1.8 3.1 12.2 2.6 1.1 15.5 5.6 3.2 17.7 9.1 2.2 5.8 20.4 19.5 3.8 6.2 10.9 4.1 9.2 10.4 3.0 4.8 7.0 4.7 1.6 3.9 3.3 5.8 4.5 7.6 2.8 5.8 3.3 2.1 2.4 2.0 14.6 6.7 1.6 3.2 1.5 1.9 9.3 5.3 5.2 3.6 5.6 3.5 3.9 1.0 1.2 14.2 2.3 30.6 4.4 13.3 11.1 1.0 21.0 16.6 8.8 3.9 21.8 3.0 2.1 5.6 7.8 14.5 23.7 21.2 18.9 13.0 11.3 12.2 14.6 13.0 13.6 SESN2 "DKFZp761M0212, HI95, SES2, SEST2" ENSG00000130766 "Sestrin 2" P58004 1 28259527-28282491 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 22.7;SK-MEL-30: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018191 Uncertain Approved Cytosol Cytosol "HPA018191: AB_1856750" "unprognostic (7.05e-2)" "unprognostic (4.95e-3)" "unprognostic (1.43e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (1.71e-1)" "prognostic unfavourable (4.78e-4)" "unprognostic (8.97e-2)" "unprognostic (2.50e-3)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.39e-2)" "unprognostic (1.71e-1)" "unprognostic (2.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-1)" 9.2 7.7 7.0 6.8 6.7 32.0 7.6 6.1 11.1 6.1 9.6 3.5 4.6 14.3 7.2 4.0 15.2 6.2 7.6 4.3 4.5 6.1 12.5 18.4 7.7 4.1 8.4 4.5 22.4 10.4 7.5 5.4 9.3 7.6 5.2 8.3 6.9 14.5 4.6 5.8 4.9 12.6 6.2 10.9 5.8 7.2 9.2 4.3 4.8 7.0 4.2 9.7 7.3 14.9 1.9 2.8 6.2 2.7 3.9 9.6 2.5 2.6 1.4 3.5 5.7 5.6 4.4 18.8 5.0 4.6 3.0 3.6 2.0 1.9 2.9 2.1 2.2 2.6 4.0 3.5 2.1 2.6 3.7 1.2 2.0 3.3 18.4 4.4 6.7 14.0 22.7 8.2 19.7 3.4 6.9 14.2 2.8 1.5 1.6 1.2 2.7 2.9 2.5 0.9 6.5 2.0 4.4 1.2 1.3 1.4 1.1 27.3 3.1 6.3 1.9 1.5 4.8 3.5 3.0 18.5 4.6 4.6 3.7 4.5 3.5 0.0 2.3 1.9 9.6 1.9 4.7 1.9 3.4 4.6 2.4 1.4 2.1 4.3 6.2 3.9 2.7 2.8 3.9 2.5 7.0 6.7 6.1 11.1 4.5 6.1 8.4 4.5 7.6 4.3 SETD1A "KIAA0339, KMT2F, Set1" ENSG00000099381 "SET domain containing 1A" O15047 16 30957294-30984664 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020646, HPA058376" Enhanced Supported "Nuclear speckles" "Nuclear speckles" "HPA020646: AB_1856752, HPA058376: AB_2683695" "unprognostic (8.62e-2)" "unprognostic (1.93e-2)" "unprognostic (3.96e-2)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.40e-2)" "prognostic unfavourable (8.47e-4)" "unprognostic (5.01e-2)" "unprognostic (1.54e-1)" "unprognostic (3.18e-1)" "unprognostic (5.77e-2)" "unprognostic (1.72e-1)" "unprognostic (1.55e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" "unprognostic (1.70e-2)" "unprognostic (1.94e-1)" 11.0 10.5 10.0 12.4 10.2 25.6 10.3 23.0 14.5 11.1 12.1 14.1 7.6 10.2 15.3 6.7 9.4 11.2 9.7 7.6 8.8 6.7 9.3 10.5 9.0 12.6 9.3 9.8 15.3 14.8 15.6 12.9 11.3 9.5 10.9 5.7 13.5 12.7 10.5 15.2 12.3 11.4 11.7 8.0 14.5 10.3 22.3 10.0 15.5 12.7 5.4 14.1 10.6 9.9 2.0 2.6 2.5 1.4 1.3 1.6 0.9 6.4 12.5 8.6 10.0 4.9 3.5 9.3 7.3 5.5 6.3 5.3 10.6 6.6 17.3 8.1 6.7 8.5 7.7 7.4 5.2 9.2 30.0 8.0 21.6 11.8 4.7 13.6 13.8 5.9 5.9 8.8 5.6 4.8 16.1 9.8 3.4 13.5 16.1 13.8 12.2 8.3 24.5 8.5 10.9 3.9 7.1 9.3 9.5 9.8 8.1 5.4 8.4 11.0 6.5 9.5 9.2 6.0 7.6 14.9 18.0 16.9 7.6 11.8 7.2 0.0 0.8 2.5 1.2 1.4 1.6 0.2 1.0 0.8 0.6 2.0 0.7 1.5 0.5 1.3 0.4 2.6 0.4 0.9 10.0 10.2 23.0 14.5 8.8 6.7 9.3 9.8 9.5 10.0 SETD1B "KIAA1076, KMT2G, Set1B" ENSG00000139718 "SET domain containing 1B" Q9UPS6 12 121804180-121832584 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021667, HPA059412" Approved Enhanced Nucleoplasm Nucleoplasm "HPA021667: AB_1856753, HPA059412: " "unprognostic (1.69e-1)" "unprognostic (2.38e-2)" "unprognostic (6.32e-2)" "unprognostic (3.51e-1)" "unprognostic (2.06e-1)" "unprognostic (2.75e-2)" "unprognostic (5.32e-2)" "unprognostic (1.35e-1)" "unprognostic (1.28e-2)" "unprognostic (5.65e-2)" "unprognostic (1.59e-2)" "unprognostic (1.75e-1)" "unprognostic (7.33e-2)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" 13.8 9.6 9.3 16.8 9.4 22.7 18.1 22.0 11.1 19.6 25.0 7.4 16.0 13.0 27.2 14.8 15.8 21.1 18.2 10.0 8.9 4.6 10.1 10.9 10.9 11.9 5.4 7.4 17.4 14.3 12.1 11.9 12.2 7.1 16.5 6.8 14.4 15.9 31.1 12.9 11.8 15.3 14.7 5.4 14.4 17.8 9.1 7.3 31.1 14.7 8.9 14.7 22.8 14.4 1.3 2.1 3.9 2.0 1.0 2.1 0.8 6.0 12.0 6.3 10.5 5.9 4.1 9.6 5.6 4.6 4.5 2.6 6.8 3.7 4.5 5.2 6.3 9.4 7.3 4.6 2.5 7.9 9.0 13.8 14.9 5.8 5.1 12.5 11.8 4.9 5.4 6.1 4.8 4.7 14.0 3.2 3.1 14.2 17.9 16.6 8.9 7.3 14.0 4.2 6.4 4.0 12.6 7.8 6.0 12.9 8.6 4.7 10.7 10.8 7.9 6.5 8.1 9.1 6.3 6.2 3.1 2.7 5.3 7.8 7.3 3.9 0.9 2.0 1.9 2.0 1.3 1.2 1.3 1.8 0.7 1.3 2.1 1.3 3.8 1.0 0.8 2.1 1.3 0.8 9.3 9.4 22.0 11.1 8.9 4.6 5.4 7.4 7.1 7.3 SETD2 "FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A" ENSG00000181555 "SET domain containing 2" Q9BYW2 3 47016429-47163967 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042451 Approved Approved "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "HPA042451: AB_10806239" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (6.08e-2)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.01e-2)" "prognostic unfavourable (8.19e-4)" "unprognostic (6.19e-2)" "unprognostic (2.45e-1)" "unprognostic (7.84e-2)" "prognostic favourable (7.99e-6)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (8.79e-2)" "unprognostic (5.43e-2)" 13.2 10.5 12.2 15.2 15.4 20.0 11.7 22.4 16.4 13.4 14.0 9.1 12.9 9.5 15.8 7.5 10.8 11.4 8.7 8.8 10.6 6.8 11.4 10.3 10.4 11.8 11.7 9.5 16.0 13.4 21.4 16.3 10.7 11.3 12.4 10.9 7.7 12.7 14.8 27.6 12.5 11.5 11.9 9.8 13.8 10.4 12.8 12.8 23.2 15.8 5.5 12.8 16.1 15.5 4.8 2.6 6.0 2.3 7.1 3.9 1.0 11.4 9.0 15.2 7.8 9.1 10.6 6.4 10.6 10.3 12.4 11.3 9.5 7.5 25.3 6.6 14.5 7.0 16.4 10.1 16.8 14.5 6.5 25.9 15.1 7.3 6.8 19.4 15.0 9.1 9.7 12.2 15.2 11.4 16.6 9.6 10.1 6.0 14.2 2.6 11.5 7.5 9.4 14.7 13.1 6.2 15.1 6.6 10.5 17.8 7.0 6.6 7.4 14.4 14.6 13.6 10.2 11.6 16.8 12.2 13.6 25.5 7.9 11.1 7.9 2.4 2.2 5.2 3.9 2.3 2.4 3.7 2.4 3.0 2.5 4.8 3.5 3.0 6.0 7.1 1.9 2.6 1.0 1.0 12.2 15.4 22.4 16.4 10.6 6.8 11.7 9.5 11.3 12.8 SETD3 "C14orf154, FLJ23027" ENSG00000183576 "SET domain containing 3" Q86TU7 14 99397746-99480889 "Enzymes, Predicted intracellular proteins" "Actin-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003591, HPA003639" Approved Approved Mitochondria Mitochondria "HPA003591: AB_1079930, HPA003639: AB_1079931" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (8.07e-2)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "prognostic unfavourable (6.46e-4)" "unprognostic (1.04e-2)" "unprognostic (3.24e-2)" "unprognostic (3.29e-1)" "unprognostic (2.73e-2)" "unprognostic (2.01e-1)" "unprognostic (4.42e-1)" "prognostic favourable (1.89e-15)" "unprognostic (6.81e-2)" "unprognostic (3.21e-1)" "unprognostic (2.20e-1)" "unprognostic (2.62e-3)" 17.1 12.5 24.7 13.3 26.8 9.2 16.6 14.6 23.8 14.3 22.7 18.7 26.9 16.2 14.2 39.6 16.9 21.7 13.4 34.1 24.1 17.9 43.4 21.0 16.7 11.9 23.7 13.9 11.7 16.9 17.4 14.5 19.4 18.4 16.9 17.6 16.2 24.9 20.2 68.7 14.1 16.5 26.0 25.3 13.7 15.4 39.1 15.3 11.5 25.6 20.3 10.9 24.0 21.4 9.2 18.6 19.9 17.4 16.0 18.2 11.3 13.7 15.9 12.0 11.4 14.0 15.8 42.7 17.5 13.4 18.4 18.8 15.3 23.5 13.6 14.4 19.7 18.0 14.6 19.7 29.4 13.3 7.8 12.3 10.3 13.9 17.5 18.5 18.6 11.0 25.9 16.3 23.9 22.8 9.7 20.5 20.2 25.9 19.2 20.1 7.1 18.1 11.7 24.6 11.1 26.3 17.1 21.5 10.0 15.7 16.4 13.4 22.2 16.1 20.1 8.3 11.5 55.8 13.3 14.7 16.6 14.6 15.6 18.4 12.6 6.4 15.0 19.9 15.5 17.4 18.2 9.2 13.4 14.5 18.6 7.6 11.2 13.9 9.4 16.0 14.8 11.7 9.7 11.3 24.7 26.8 14.6 23.8 24.1 17.9 23.7 13.9 18.4 15.3 SETD7 "KIAA1717, KMT7, SET7, SET7/9, Set9" ENSG00000145391 "SET domain containing lysine methyltransferase 7" Q8WTS6 4 139495941-139606699 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058111 Enhanced Enhanced Nucleoli Nucleoli "HPA058111: " "prognostic unfavourable (8.28e-4)" "unprognostic (7.07e-2)" "unprognostic (4.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.92e-1)" "unprognostic (4.82e-2)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.71e-2)" "unprognostic (9.10e-2)" "unprognostic (6.44e-2)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (6.16e-3)" "unprognostic (1.17e-1)" "unprognostic (6.92e-2)" "unprognostic (6.56e-3)" 26.1 13.2 12.0 9.6 12.3 5.7 26.3 10.2 16.2 27.9 17.7 17.9 11.0 4.8 23.8 12.0 18.3 13.8 16.9 25.2 13.0 10.0 7.2 30.7 12.1 6.9 18.0 10.1 13.3 13.8 26.8 9.3 12.0 15.4 22.8 10.2 12.4 13.7 13.9 56.4 14.2 9.9 33.3 19.0 11.8 17.7 10.6 16.5 2.9 10.3 15.2 9.9 24.2 30.1 2.3 6.8 1.8 5.6 0.5 5.6 1.6 8.9 11.5 4.4 2.6 26.1 22.5 9.7 21.2 22.0 10.8 9.2 6.8 12.2 20.8 8.4 35.6 4.5 14.6 16.7 17.7 10.2 10.3 2.9 15.0 0.2 12.9 9.9 4.4 19.5 19.6 17.2 18.4 13.7 1.7 32.3 13.8 14.9 6.5 1.5 2.1 7.6 6.1 15.3 11.9 10.5 8.2 17.2 5.7 14.1 20.9 5.0 8.3 9.1 22.2 19.2 13.6 22.9 17.5 28.0 26.8 13.2 22.1 10.0 9.2 1.0 5.6 0.5 0.6 3.2 4.1 1.8 1.8 1.8 6.8 2.3 0.8 0.5 1.8 0.5 4.8 3.5 5.6 1.6 12.0 12.3 10.2 16.2 13.0 10.0 18.0 10.1 15.4 16.5 SETDB1 "ESET, KG1T, KIAA0067, KMT1E, TDRD21" ENSG00000143379 "SET domain bifurcated 1" Q15047 1 150926263-150964744 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "U-698: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018142, HPA058484" Uncertain Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA018142: AB_1856757, HPA058484: " "unprognostic (1.07e-1)" "unprognostic (4.08e-1)" "unprognostic (8.02e-2)" "unprognostic (2.24e-3)" "unprognostic (1.65e-2)" "unprognostic (9.57e-2)" "prognostic unfavourable (8.88e-4)" "unprognostic (6.03e-2)" "unprognostic (9.94e-3)" "unprognostic (7.13e-2)" "unprognostic (1.21e-1)" "unprognostic (6.65e-2)" "prognostic unfavourable (4.25e-4)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" 16.9 15.4 9.5 21.2 15.9 16.9 17.7 21.6 18.2 18.6 15.4 25.2 18.6 13.0 22.8 18.9 15.6 16.8 14.0 10.9 9.6 8.5 13.3 12.7 15.6 20.7 15.3 13.2 23.9 17.6 21.0 15.4 18.4 13.7 14.9 16.8 20.6 16.1 18.5 20.0 18.0 17.1 17.9 13.7 21.9 15.0 33.5 14.2 24.5 18.6 12.0 20.7 18.6 16.3 11.2 12.8 6.9 14.9 7.6 9.1 5.3 5.7 6.7 9.8 6.4 4.7 6.3 16.3 4.8 5.5 6.9 5.9 4.5 8.0 11.4 6.6 5.3 7.3 9.1 5.1 5.5 5.5 11.3 6.4 6.9 5.2 6.7 11.3 6.1 8.2 5.8 5.7 9.2 8.1 10.8 9.3 4.9 11.1 7.8 6.6 13.4 5.4 9.1 6.3 8.4 5.3 6.6 7.1 13.0 7.3 8.6 5.8 9.3 15.4 5.4 4.0 4.2 4.4 6.7 9.7 10.4 88.6 4.2 4.0 3.9 6.8 10.7 6.9 8.3 14.9 8.7 8.7 7.4 9.1 12.8 11.2 8.3 8.3 6.5 7.6 10.6 8.6 4.7 5.3 9.5 15.9 21.6 18.2 9.6 8.5 15.3 13.2 13.7 14.2 SETDB2 "C13orf4, CLLD8, CLLL8, KMT1F" ENSG00000136169 "SET domain bifurcated 2" Q96T68 13 49444374-49495003 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012190, HPA071677" Approved Approved Nucleoplasm Nucleoplasm "CAB012190: AB_2186195, HPA071677: " "unprognostic (1.77e-1)" "unprognostic (1.11e-2)" "unprognostic (1.58e-1)" "unprognostic (3.61e-2)" "unprognostic (4.20e-1)" "unprognostic (3.70e-3)" "unprognostic (3.74e-2)" "unprognostic (3.44e-3)" "unprognostic (7.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.09e-3)" "unprognostic (7.95e-2)" "prognostic favourable (1.92e-7)" "unprognostic (2.83e-2)" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.85e-1)" 10.2 14.5 9.8 20.5 10.8 9.5 14.1 14.4 12.3 13.0 12.4 8.3 13.6 7.8 13.1 11.6 9.8 9.9 9.7 12.7 8.2 6.9 12.4 11.0 16.3 19.0 7.2 11.1 21.0 15.0 10.8 15.8 7.8 9.5 13.6 11.9 13.5 11.7 10.9 5.5 9.6 11.4 11.3 8.4 19.0 10.7 18.1 8.7 17.3 14.6 3.7 16.6 11.9 10.3 8.4 7.4 4.7 5.4 7.8 10.2 4.5 2.0 1.3 4.2 4.3 6.0 6.7 2.1 5.8 7.3 5.2 4.9 8.5 4.9 25.1 1.1 3.7 4.2 4.4 3.9 5.1 5.7 3.9 8.7 3.8 5.1 8.4 13.3 5.0 5.2 7.2 4.0 13.1 4.4 3.8 3.5 4.7 1.7 5.0 9.9 2.2 3.4 9.8 5.3 5.3 4.8 1.9 2.1 2.5 2.5 3.6 12.4 3.0 11.5 2.6 5.0 1.8 6.6 2.3 4.3 5.8 13.3 1.5 10.8 2.3 4.1 4.1 4.7 6.9 5.4 5.8 8.4 7.1 7.1 7.4 8.1 10.2 7.6 1.4 7.8 4.3 5.2 9.4 4.5 9.8 10.8 14.4 12.3 8.2 6.9 7.2 11.1 9.5 8.7 SETMAR metnase ENSG00000170364 "SET domain and mariner transposase fusion gene" Q53H47 3 4303304-4317567 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Methyltransferase, Multifunctional enzyme, Nuclease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA057999 Supported Nucleoli Nucleoli "HPA057999: " "unprognostic (1.59e-1)" "unprognostic (1.22e-2)" "unprognostic (5.24e-3)" "unprognostic (4.89e-2)" "unprognostic (7.73e-2)" "unprognostic (4.73e-2)" "prognostic unfavourable (2.85e-4)" "unprognostic (1.58e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-1)" "unprognostic (1.19e-3)" "unprognostic (1.19e-1)" "prognostic favourable (6.61e-6)" "unprognostic (5.42e-1)" "unprognostic (3.06e-2)" "unprognostic (1.08e-1)" "unprognostic (1.26e-3)" 14.1 6.2 7.3 7.2 9.2 3.7 14.2 6.9 8.5 12.5 6.5 6.2 5.2 4.3 19.4 7.6 7.2 12.5 8.2 6.3 6.6 4.3 10.1 5.3 5.1 6.5 9.1 8.7 19.4 9.8 5.7 7.4 5.6 6.5 13.9 6.9 5.7 11.9 10.0 7.7 7.3 5.7 16.8 7.2 5.0 6.0 7.3 10.8 13.1 11.5 8.3 4.4 11.3 13.3 3.8 1.6 1.9 3.3 0.5 5.3 1.5 2.9 2.7 8.1 1.7 19.4 6.5 8.2 3.3 1.0 3.2 3.1 2.8 2.3 7.9 3.5 1.8 2.6 7.1 5.0 3.6 5.3 6.1 9.8 4.8 4.5 2.2 4.6 4.2 7.6 3.8 2.4 0.8 4.7 6.5 3.0 5.0 4.1 6.9 2.9 7.9 4.6 8.1 8.0 3.2 3.0 4.1 6.4 9.5 4.0 5.0 4.2 4.7 2.7 3.1 4.9 6.8 4.1 4.3 3.9 9.4 19.5 1.7 5.3 4.0 1.9 1.1 1.3 2.3 3.3 2.0 2.9 2.7 2.9 1.0 3.8 4.5 5.3 0.2 0.5 1.9 1.6 1.7 1.5 7.3 9.2 6.9 8.5 6.6 4.3 9.1 8.7 6.5 10.8 SGK1 SGK ENSG00000118515 "Serum/glucocorticoid regulated kinase 1" O00141 6 134169246-134318112 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 141.3" "Cell line enhanced" "Detected in many" "HHSteC: 50.1;RPTEC TERT1: 76.9;SK-MEL-30: 49.8;TIME: 59.8;U-266/84: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.7;eosinophil: 45.9;neutrophil: 26.2" "Group enriched" "Detected in many" 7 "granulocytes: 45.9;monocytes: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022085, CAB025148, HPA051251" Approved Enhanced "Nuclear speckles" "Nuclear speckles" "CAB022085: , CAB025148: , HPA051251: " "unprognostic (2.05e-2)" "prognostic favourable (5.26e-4)" "unprognostic (1.12e-1)" "unprognostic (5.09e-3)" "unprognostic (2.76e-1)" "unprognostic (4.20e-2)" "unprognostic (4.53e-2)" "unprognostic (5.62e-2)" "unprognostic (4.03e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (2.55e-1)" "unprognostic (5.82e-3)" "unprognostic (9.10e-2)" "unprognostic (3.81e-2)" "unprognostic (1.79e-1)" "unprognostic (6.59e-2)" 45.6 35.5 16.8 12.8 43.2 15.8 22.9 10.6 25.0 18.4 62.3 51.7 10.8 14.2 14.9 11.2 30.0 16.1 47.8 12.5 22.9 9.6 37.5 51.1 31.2 8.4 48.8 16.6 47.2 47.8 141.3 4.7 19.2 28.3 18.3 11.3 45.8 26.2 18.4 12.4 25.8 131.8 13.6 40.3 7.6 31.1 12.2 50.1 6.2 22.3 24.8 20.4 26.1 31.7 0.6 4.0 45.9 11.7 0.9 0.7 3.1 0.6 1.1 0.7 0.0 8.6 2.1 0.9 12.3 25.7 16.1 13.2 1.9 1.7 2.0 1.8 12.7 0.4 1.1 1.9 11.9 0.0 0.5 0.1 30.7 1.4 50.1 0.1 1.1 12.9 12.4 15.8 20.6 27.0 3.9 31.4 5.7 0.1 0.1 0.4 0.7 1.3 0.3 1.4 0.2 76.9 0.2 0.3 3.0 38.7 0.1 49.8 0.0 0.3 59.8 4.7 2.0 28.9 2.7 5.9 54.8 6.3 4.4 1.9 6.3 0.6 11.7 45.9 0.2 6.8 0.5 0.6 0.4 0.2 4.0 0.4 0.5 0.6 26.2 0.9 3.7 0.2 0.7 3.1 16.8 43.2 10.6 25.0 22.9 9.6 48.8 16.6 28.3 50.1 SGK2 ENSG00000101049 "SGK2, serine/threonine kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.1;kidney: 39.1;liver: 32.9" "Group enriched" "Detected in some" 5 "A549: 13.5;CAPAN-2: 10.6;EFO-21: 5.4;Hep G2: 13.7;RPTEC TERT1: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm Nucleoplasm "HPA008859: , HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favourable (5.65e-4)" 11.4 0.7 2.8 4.3 9.9 0.2 3.1 1.0 10.2 1.4 21.3 33.1 0.9 17.8 1.0 19.7 0.7 1.6 7.9 0.7 4.3 2.5 39.1 32.9 0.6 0.5 6.9 5.1 3.2 14.1 0.5 1.7 0.5 13.7 1.4 23.4 0.0 0.9 1.8 0.4 3.2 20.7 1.0 14.2 0.7 11.9 1.0 6.0 0.0 1.0 0.2 0.2 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.6 10.6 0.0 5.4 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 13.7 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 19.4 2.2 0.1 0.5 0.0 0.9 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 9.9 1.0 10.2 4.3 2.5 6.9 5.1 13.7 6.0 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66667596-66862022 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006699, HPA027146" Supported Supported Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favourable (5.52e-6)" "prognostic favourable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favourable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 6.5 5.9 13.9 8.7 20.9 7.7 23.9 9.8 14.8 12.0 10.0 24.0 8.7 8.6 8.0 10.3 7.6 7.8 7.8 5.4 16.1 10.2 14.9 13.6 9.9 8.5 28.8 9.3 9.8 15.6 29.2 14.8 5.9 14.6 7.8 10.7 17.2 7.0 7.7 6.1 12.4 10.8 6.0 32.8 8.2 7.2 8.9 21.9 8.3 17.3 4.3 6.8 6.1 8.0 5.8 13.8 21.4 15.7 6.9 13.3 8.0 11.4 2.9 0.5 1.8 3.5 6.8 6.5 7.3 6.9 4.0 4.2 5.2 7.7 8.6 1.8 8.0 3.7 6.0 4.3 5.0 4.8 10.2 7.8 2.1 5.1 3.5 7.0 9.3 3.3 3.8 1.9 6.7 6.4 1.5 4.2 7.6 1.8 5.5 4.3 1.6 4.0 9.7 4.3 5.8 5.4 2.6 2.5 1.9 3.3 4.9 11.0 23.1 14.0 7.6 3.8 3.4 3.3 2.7 5.2 9.9 9.9 4.4 11.8 3.9 21.4 15.7 6.2 8.1 9.3 13.3 3.7 8.4 8.5 13.8 5.8 9.0 6.9 2.5 6.9 4.4 7.7 5.3 8.0 13.9 20.9 9.8 14.8 16.1 10.2 28.8 9.3 14.6 21.9 SGMS2 "MGC26963, SMS2" ENSG00000164023 "Sphingomyelin synthase 2" Q8NHU3 4 107824563-107915047 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "pons and medulla: 17.0" "Group enriched" "Detected in some" 8 "classical monocyte: 5.7;eosinophil: 3.9;intermediate monocyte: 2.4;myeloid DC: 6.6;non-classical monocyte: 2.0" "Group enriched" "Detected in many" 32 "dendritic cells: 6.6;granulocytes: 3.9;monocytes: 5.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA015076 Supported "HPA015076: AB_1857298" "unprognostic (7.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.36e-2)" "unprognostic (1.87e-2)" "unprognostic (7.88e-3)" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (1.32e-1)" "unprognostic (4.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.82e-3)" "unprognostic (3.26e-1)" "prognostic favourable (1.37e-4)" "unprognostic (6.18e-2)" "unprognostic (5.63e-2)" "unprognostic (8.71e-2)" "unprognostic (5.22e-3)" 7.5 3.3 1.9 8.6 2.9 2.1 8.0 1.7 1.9 8.3 22.2 3.4 5.6 11.4 12.5 9.7 14.9 7.5 24.9 7.8 2.5 2.6 13.2 12.6 20.7 6.4 2.7 1.4 5.4 8.4 4.6 48.5 30.7 17.0 8.0 6.4 11.8 14.2 3.2 5.0 4.5 38.1 18.5 4.6 1.5 9.8 8.6 1.0 0.2 22.0 12.2 5.3 10.7 11.2 0.1 6.6 3.9 5.7 0.0 0.1 1.4 9.9 3.8 0.5 2.9 6.6 15.4 0.2 12.3 9.3 5.8 6.1 1.7 20.7 0.7 4.9 19.4 3.7 7.1 10.8 10.4 2.8 2.8 0.4 8.4 0.5 7.6 6.7 0.0 5.3 7.6 11.3 13.8 12.8 0.1 0.2 9.2 3.3 0.2 0.0 0.3 4.2 0.2 5.0 1.4 15.5 4.9 1.0 0.0 9.3 13.4 1.6 7.2 0.1 21.8 7.0 11.1 10.0 5.6 0.7 0.2 0.4 9.4 1.6 2.9 0.0 5.7 3.9 0.0 2.4 0.0 0.1 0.0 0.0 6.6 0.1 0.1 0.0 0.5 0.0 2.0 0.0 0.0 1.4 1.9 2.9 1.7 1.9 2.5 2.6 2.7 1.4 17.0 1.0 SGPL1 SPL ENSG00000166224 "Sphingosine-1-phosphate lyase 1" O95470 10 70815961-70881173 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021125, HPA023086" Enhanced Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA021125: AB_1856803, HPA023086: AB_1856804" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (7.60e-2)" "unprognostic (2.98e-2)" "unprognostic (2.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (2.12e-1)" "unprognostic (9.52e-2)" "unprognostic (3.42e-1)" "unprognostic (2.14e-1)" "unprognostic (9.21e-2)" "unprognostic (4.68e-3)" 9.6 11.2 12.0 20.2 11.4 4.9 24.4 10.8 10.6 16.2 17.1 16.0 21.9 13.3 15.5 16.8 26.7 13.5 13.4 8.3 11.3 9.8 18.2 27.1 10.4 20.1 11.9 9.5 10.0 34.6 15.4 10.2 11.3 10.4 16.1 15.6 7.6 15.0 19.5 7.6 28.6 32.5 12.1 15.7 22.9 10.3 15.3 11.0 14.7 17.6 12.8 18.0 21.4 26.8 5.6 9.7 8.9 24.8 10.9 11.5 6.6 10.5 14.1 13.6 15.5 3.7 4.9 9.0 6.2 6.7 6.8 8.9 15.3 23.4 9.5 7.4 6.3 17.8 11.7 12.5 9.7 15.2 6.2 0.9 7.2 18.2 14.2 4.1 8.6 9.2 21.2 9.1 24.0 4.2 2.8 8.3 9.6 11.7 5.0 2.8 6.1 7.8 6.5 10.4 3.5 10.8 44.8 9.3 11.3 12.4 19.1 11.3 9.9 3.0 8.1 6.1 16.2 4.7 11.9 3.4 4.7 4.4 6.1 7.7 4.3 0.6 11.5 7.9 11.5 20.3 10.4 4.7 7.5 9.4 9.7 5.6 5.7 9.0 8.9 10.9 24.8 5.4 6.8 6.6 12.0 11.4 10.8 10.4 11.3 9.8 11.9 9.5 10.4 11.0 SGSH "HSS, MPS3A, SFMD" ENSG00000181523 "N-sulfoglucosamine sulfohydrolase" P51688 17 80206716-80220923 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 27.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023436, HPA023451" Enhanced "Intracellular and membrane" "HPA023436: AB_1856806, HPA023451: AB_1856807" "unprognostic (4.33e-2)" "unprognostic (4.03e-2)" "unprognostic (1.06e-2)" "unprognostic (4.01e-2)" "unprognostic (4.26e-3)" "unprognostic (1.39e-3)" "prognostic unfavourable (7.71e-4)" "prognostic favourable (2.72e-4)" "unprognostic (6.08e-2)" "unprognostic (3.65e-1)" "prognostic favourable (3.10e-4)" "unprognostic (2.05e-1)" "prognostic unfavourable (2.66e-4)" "unprognostic (1.42e-2)" "prognostic unfavourable (5.37e-4)" "unprognostic (7.50e-2)" "unprognostic (3.68e-2)" 14.4 37.1 7.8 11.6 7.5 2.3 13.5 5.5 7.3 12.0 11.2 9.3 16.5 8.5 13.8 14.8 11.2 13.2 14.2 8.5 7.9 9.3 16.3 9.9 15.1 19.9 5.5 6.7 11.3 19.5 16.5 13.8 19.2 7.7 17.2 5.8 18.1 18.8 19.5 6.1 14.9 12.3 11.2 6.8 23.3 13.2 8.1 6.7 3.6 16.6 11.4 16.1 14.5 8.9 3.9 16.0 1.8 16.1 6.4 14.4 9.5 1.2 3.7 3.2 6.6 9.2 8.3 4.7 8.2 16.2 11.4 10.4 3.2 4.2 0.0 13.4 7.0 4.0 2.0 3.4 2.1 3.9 5.1 0.0 9.2 9.2 27.9 0.0 2.9 15.8 4.2 3.3 4.4 22.4 3.5 9.3 6.1 6.4 0.1 0.1 2.0 6.5 0.5 1.7 9.6 7.1 6.4 0.9 6.6 9.2 17.2 4.4 15.4 0.2 15.4 13.3 3.8 5.0 2.9 15.4 1.8 1.6 6.1 0.0 6.5 0.0 16.1 0.0 10.9 6.8 14.4 3.1 9.2 10.8 16.0 3.9 7.5 6.3 1.8 6.4 6.0 1.1 10.9 9.5 7.8 7.5 5.5 7.3 7.9 9.3 5.5 6.7 7.7 6.7 SH3RF1 "KIAA1494, POSH, RNF142, SH3MD2" ENSG00000154447 "SH3 domain containing ring finger 1" Q7Z6J0 4 169094256-169271105 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 5.9;myeloid DC: 3.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 13 "dendritic cells: 3.4;monocytes: 8.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074783 Approved Supported "Vesicles,Intermediate filaments" Vesicles "Intermediate filaments" "HPA074783: " "unprognostic (4.14e-1)" "unprognostic (4.67e-2)" "unprognostic (1.23e-1)" "unprognostic (7.83e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (8.44e-2)" "unprognostic (9.58e-2)" "unprognostic (4.77e-3)" "unprognostic (7.88e-2)" "prognostic favourable (5.51e-8)" "unprognostic (4.43e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-1)" 15.2 4.8 13.8 7.2 11.8 3.7 11.1 2.5 12.7 7.5 17.2 15.9 10.8 15.7 6.8 7.2 7.1 6.9 19.7 7.8 17.8 9.3 14.6 9.6 11.3 3.7 13.0 10.9 11.9 12.0 5.2 7.8 8.6 10.3 17.2 16.0 10.7 20.9 10.7 16.2 6.8 17.2 8.8 11.7 4.5 27.6 7.0 11.3 0.9 23.1 7.6 5.5 9.4 6.3 0.4 3.4 0.0 8.5 0.3 0.0 0.7 7.3 6.2 5.6 16.2 6.1 7.6 7.3 20.6 10.0 15.4 7.1 6.1 8.9 0.0 1.0 21.4 4.9 4.5 8.1 17.0 0.0 2.6 4.3 14.1 3.2 13.8 1.5 0.1 4.5 4.5 13.1 10.4 9.4 0.0 0.0 14.2 3.0 1.5 1.4 2.8 5.3 2.3 1.8 0.3 7.0 5.8 4.2 5.1 5.2 8.0 2.0 2.6 0.6 8.5 7.3 5.7 12.1 7.2 0.5 0.0 0.0 8.2 1.5 8.7 0.0 1.4 0.0 0.0 5.9 0.0 0.4 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.3 8.5 0.2 0.0 0.7 13.8 11.8 2.5 12.7 17.8 9.3 13.0 10.9 10.3 11.3 SH3RF2 "FLJ23654, Hepp1, POSHER, PPP1R39, RNF158" ENSG00000156463 "SH3 domain containing ring finger 2" Q8TEC5 5 145936579-146081791 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 40.8" "Cell line enhanced" "Detected in some" "A-431: 10.5;CACO-2: 35.8;HBEC3-KT: 11.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basal ganglia: 11.5;cerebral cortex: 2.9" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 4 "dendritic cells: 1.4;T-cells: 1.6" "Region enriched" "Detected in single" 14 "basal ganglia: 23.9" "Region enhanced" "Detected in many" "basal ganglia: 14.5" "HPA035903, HPA058119" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA035903: AB_10696515, HPA058119: " "unprognostic (8.90e-3)" "unprognostic (2.00e-3)" "unprognostic (5.11e-3)" "unprognostic (1.66e-2)" "unprognostic (1.45e-3)" "unprognostic (1.47e-2)" "unprognostic (9.96e-3)" "unprognostic (8.22e-2)" "unprognostic (3.92e-1)" "unprognostic (7.37e-3)" "unprognostic (2.44e-3)" "unprognostic (1.66e-1)" "unprognostic (2.98e-2)" "unprognostic (5.21e-2)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.13e-3)" 2.6 0.6 1.2 6.2 11.5 0.0 2.9 0.2 2.9 6.4 19.1 0.4 0.4 9.2 2.9 2.2 22.2 3.6 40.8 23.5 0.8 0.3 0.8 4.6 1.9 0.0 0.3 1.1 1.0 14.3 0.0 3.3 0.3 0.1 2.2 8.5 0.9 16.9 1.0 21.7 33.1 21.4 1.2 0.5 0.2 11.9 6.4 0.6 0.6 3.8 19.6 16.1 0.9 10.0 0.0 1.4 0.3 0.1 0.0 1.6 0.3 10.5 2.9 0.1 0.6 0.0 0.0 0.0 0.1 0.8 2.2 0.9 35.8 9.9 0.0 5.6 0.4 9.8 0.0 11.5 2.1 0.1 0.1 0.0 4.2 4.8 0.6 0.0 0.0 0.1 6.2 3.3 7.9 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.8 0.0 0.1 0.0 4.6 1.0 0.0 0.0 0.6 0.2 0.2 3.4 0.0 5.0 0.4 9.2 0.8 3.4 0.0 0.0 0.0 5.6 0.0 0.1 0.3 0.0 0.0 1.2 0.0 0.0 0.0 1.6 0.7 1.4 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.8 0.3 1.2 11.5 0.2 2.9 0.8 0.3 0.3 1.1 0.1 0.6 SHMT1 "CSHMT, MGC15229, MGC24556, SHMT" ENSG00000176974 "Serine hydroxymethyltransferase 1" P34896 17 18327860-18363563 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 57.8;liver: 108.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" HPA023314 Enhanced Supported Nucleoplasm,Cytosol 240000 "Nucleoplasm, Cytosol" "HPA023314: AB_1856830" "unprognostic (4.76e-2)" "unprognostic (1.98e-2)" "unprognostic (5.46e-2)" "unprognostic (3.76e-1)" "unprognostic (2.45e-1)" "unprognostic (8.44e-3)" "prognostic favourable (2.52e-4)" "unprognostic (7.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "prognostic favourable (8.54e-6)" "unprognostic (1.70e-2)" "unprognostic (2.66e-1)" "unprognostic (2.57e-3)" "unprognostic (4.04e-2)" 10.9 3.2 2.2 4.9 4.1 2.1 10.4 6.5 3.0 4.6 15.2 5.3 7.3 12.3 2.8 7.4 16.3 3.9 4.0 2.0 2.6 1.8 57.8 108.3 4.3 3.8 3.5 1.9 4.1 3.5 30.1 1.6 2.8 3.6 3.4 3.5 7.2 9.8 8.0 5.7 6.2 15.1 2.3 2.9 8.6 3.9 6.3 3.8 11.1 10.9 10.8 8.7 4.3 6.3 8.6 6.7 6.2 10.6 13.0 18.7 7.9 23.7 24.1 7.6 12.0 19.5 12.2 28.3 5.0 6.2 16.9 18.7 23.9 10.6 18.5 15.0 4.3 23.5 16.0 20.2 9.6 11.0 23.3 8.3 18.9 18.0 4.9 5.5 9.0 10.1 8.0 13.1 5.9 11.6 7.0 4.2 6.0 17.5 27.4 7.6 9.6 7.9 22.5 30.3 15.7 26.9 16.2 10.5 5.5 34.2 6.5 8.6 26.6 7.8 2.7 3.3 9.8 29.9 15.8 8.6 8.2 7.4 6.4 13.0 7.8 6.0 8.2 6.2 10.1 10.6 17.1 8.6 12.3 12.8 6.7 6.9 12.3 13.0 0.1 13.0 7.5 3.1 18.7 7.9 2.2 4.1 6.5 3.0 2.6 1.8 3.5 1.9 3.6 3.8 SHMT2 SHMT ENSG00000182199 "Serine hydroxymethyltransferase 2" P34897 12 57229327-57234935 "Enzymes, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 103.1" "Cell line enhanced" "Detected in all" "RH-30: 208.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020543, HPA020549" Enhanced Enhanced Microtubules,Mitochondria 160000 Mitochondria Microtubules "HPA020543: AB_1856833, HPA020549: AB_1856834" "prognostic unfavourable (8.37e-5)" "unprognostic (1.24e-1)" "unprognostic (1.90e-1)" "unprognostic (2.65e-2)" "unprognostic (1.65e-1)" "unprognostic (4.97e-2)" "unprognostic (1.58e-2)" "unprognostic (9.83e-2)" "unprognostic (1.11e-2)" "unprognostic (2.67e-2)" "unprognostic (4.00e-2)" "unprognostic (3.19e-2)" "prognostic unfavourable (4.84e-8)" "unprognostic (3.05e-1)" "unprognostic (2.30e-1)" "unprognostic (2.72e-1)" "unprognostic (4.74e-2)" 13.0 13.5 5.9 15.0 7.1 12.6 9.5 9.6 9.5 10.5 11.5 6.1 5.0 13.4 10.2 8.5 22.1 8.6 10.3 11.0 6.5 5.4 15.5 103.1 11.8 18.7 8.7 4.6 17.9 38.9 4.5 8.1 16.8 6.5 10.3 9.4 7.1 44.6 5.7 16.5 13.7 11.5 9.9 7.6 23.5 13.4 5.4 6.3 26.1 13.2 19.0 25.6 11.2 13.8 33.6 14.5 6.5 11.7 9.7 48.7 12.3 24.6 11.4 11.6 30.6 9.1 14.0 23.0 13.4 21.8 17.9 16.5 16.4 11.9 45.7 22.2 16.5 15.8 20.9 21.7 9.7 25.5 18.6 18.8 7.0 11.6 67.4 31.1 16.7 17.9 31.6 14.4 48.2 17.8 19.7 43.5 13.6 16.2 24.7 17.0 9.9 18.6 16.7 208.3 42.3 9.0 11.4 24.9 11.9 7.0 16.5 48.4 22.4 38.3 11.2 7.3 14.8 9.4 18.1 58.3 31.9 38.8 15.7 29.0 13.0 6.5 9.8 5.9 6.9 11.7 8.0 33.6 12.1 7.4 14.5 32.4 5.3 5.4 0.5 9.7 7.5 4.8 48.7 12.3 5.9 7.1 9.6 9.5 6.5 5.4 8.7 4.6 6.5 6.3 SHPK "CARKL, SHK" ENSG00000197417 Sedoheptulokinase Q9UHJ6 17 3608262-3636322 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA024361, HPA064939" Enhanced Approved "Nucleoplasm,Nuclear speckles" 150000 "Nucleoplasm, Nuclear speckles" "HPA024361: AB_1846030, HPA064939: " "unprognostic (1.75e-2)" "unprognostic (1.51e-2)" "unprognostic (3.53e-2)" "unprognostic (1.23e-2)" "unprognostic (3.57e-3)" "unprognostic (1.54e-2)" "unprognostic (1.95e-2)" "unprognostic (3.01e-2)" "unprognostic (1.56e-1)" "unprognostic (3.64e-2)" "unprognostic (1.08e-2)" "unprognostic (1.42e-1)" "unprognostic (3.82e-2)" "unprognostic (6.75e-2)" "unprognostic (1.55e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" 8.9 12.9 7.6 6.2 10.6 5.9 8.9 17.3 12.3 8.8 14.1 14.9 8.8 18.5 10.7 6.1 11.6 7.6 5.3 5.9 7.0 5.5 14.3 26.7 6.3 5.3 12.0 4.5 10.2 13.7 11.8 6.2 8.6 9.8 7.4 8.6 12.3 8.9 9.4 7.5 12.1 22.8 5.1 6.7 6.1 9.7 5.2 13.0 7.7 7.7 4.0 7.6 7.5 9.6 5.2 7.1 5.1 4.8 6.4 7.5 5.4 5.2 10.7 11.5 7.3 4.8 4.8 6.4 3.5 3.2 6.9 4.2 18.5 4.9 6.2 7.9 6.8 10.3 15.2 11.5 5.1 10.0 14.8 6.8 9.2 13.2 5.7 5.9 9.7 8.1 5.5 7.6 5.2 13.0 9.0 8.0 6.7 9.4 7.5 4.6 5.8 7.2 10.4 6.0 9.9 9.8 6.8 3.3 8.8 12.9 12.0 3.6 10.7 3.5 9.3 10.6 5.1 10.2 8.5 2.7 3.4 4.1 11.5 5.3 5.4 3.3 4.7 5.1 4.6 4.8 4.7 5.2 4.2 3.7 6.5 4.0 7.5 4.7 0.9 6.4 4.1 7.1 3.6 5.4 7.6 10.6 17.3 12.3 7.0 5.5 12.0 4.5 9.8 13.0 SHPRH "bA545I5.2, FLJ90837, KIAA2023" ENSG00000146414 "SNF2 histone linker PHD RING helicase" Q149N8 6 145864245-145964423 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Helicase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034854, HPA034950" Approved Approved Mitochondria Mitochondria "HPA034854: AB_10964488, HPA034950: " "unprognostic (3.10e-2)" "unprognostic (4.46e-2)" "unprognostic (5.61e-3)" "unprognostic (1.53e-2)" "unprognostic (7.40e-3)" "unprognostic (2.20e-2)" "unprognostic (2.63e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (5.03e-1)" "unprognostic (7.90e-2)" "unprognostic (6.01e-3)" "unprognostic (3.29e-2)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" "unprognostic (3.01e-1)" 10.9 7.3 8.3 11.0 10.0 5.5 10.4 38.0 11.5 10.6 8.0 4.5 10.8 6.0 14.1 9.2 8.5 9.8 6.7 7.2 7.2 4.2 8.4 6.5 7.1 9.0 7.6 5.9 18.8 8.7 11.4 19.7 6.6 8.5 8.3 7.4 7.3 10.2 13.7 11.4 13.9 8.2 11.0 10.3 8.8 8.5 10.7 8.7 8.4 12.5 7.2 8.0 10.7 11.5 6.7 4.8 4.4 2.4 3.4 4.3 1.2 2.9 2.3 11.4 6.7 5.3 5.7 5.5 3.5 2.9 4.4 5.7 5.2 2.1 10.4 4.4 2.7 5.1 7.0 5.0 5.8 4.7 8.0 10.5 5.2 4.4 4.0 22.0 6.5 3.9 5.8 4.1 6.0 4.7 14.6 5.9 3.7 2.6 14.1 8.2 7.7 4.0 10.2 17.8 3.5 6.0 2.9 9.4 6.6 6.3 5.8 3.9 3.1 10.6 5.2 2.8 5.3 5.5 4.1 4.8 6.8 12.4 2.9 9.5 4.3 1.6 2.3 4.4 4.3 2.4 3.7 3.9 3.6 2.9 2.7 6.7 4.1 3.3 0.1 3.4 2.4 4.8 3.3 1.2 8.3 10.0 38.0 11.5 7.2 4.2 7.6 5.9 8.5 8.7 SI ENSG00000090402 Sucrase-isomaltase P14410 3 164978898-165078495 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 123 "intestine: 181.4" "Cell line enhanced" "Detected in some" "BEWO: 2.8;CACO-2: 4.0;HeLa: 3.1;NB-4: 3.3;RPMI-8226: 4.8;SH-SY5Y: 2.9" "Cancer enhanced" "Detected in some" "stomach cancer: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011897 Enhanced "HPA011897: AB_1856840" "unprognostic (2.71e-2)" "unprognostic (1.62e-2)" "unprognostic (2.68e-1)" "unprognostic (2.05e-1)" "unprognostic (4.41e-2)" 0.1 0.1 0.1 1.4 0.1 0.0 0.1 0.1 0.1 0.1 93.3 0.0 0.0 94.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 5.4 0.0 0.1 0.0 0.1 0.1 181.4 0.0 0.1 0.1 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 32.6;ASC TERT1: 33.9;HSkMC: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" 1800000 "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favourable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favourable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 9.0 12.3 9.0 6.7 13.4 1.9 8.2 8.2 16.8 7.0 46.7 15.7 7.3 16.8 5.9 17.8 10.2 9.9 8.4 23.0 10.3 17.6 42.5 28.3 10.7 2.8 18.2 8.1 5.1 11.2 32.4 13.1 7.8 31.4 10.7 51.7 9.9 15.9 8.3 17.3 6.7 25.5 5.4 19.9 7.9 9.3 5.6 8.1 1.9 46.1 11.1 7.0 9.8 4.7 2.7 4.1 8.6 5.8 1.2 4.3 3.2 3.1 4.9 2.9 12.5 32.6 33.9 7.6 6.0 8.5 1.5 0.9 3.7 21.7 1.9 8.8 7.5 6.1 4.5 6.6 1.5 9.0 1.4 3.0 1.5 3.9 15.4 0.5 2.7 36.3 9.0 4.1 6.2 10.8 2.4 13.5 5.2 5.7 0.2 1.4 1.8 10.2 1.1 0.1 3.3 18.6 4.4 1.0 1.9 16.3 6.7 2.8 13.1 2.9 12.0 8.7 1.6 9.6 1.4 3.6 2.6 0.4 3.1 1.6 3.5 8.6 5.6 0.3 1.9 4.2 2.2 2.4 3.1 2.0 4.1 2.7 4.3 3.4 1.2 1.2 5.8 2.5 2.2 3.2 9.0 13.4 8.2 16.8 10.3 17.6 18.2 8.1 31.4 8.1 SIAH1 hSIAH1 ENSG00000196470 "Siah E3 ubiquitin protein ligase 1" Q8IUQ4 16 48356364-48448402 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 102.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018724 Enhanced Approved Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB018724: AB_2188865" "unprognostic (7.08e-2)" "unprognostic (1.16e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-3)" "unprognostic (1.25e-2)" "unprognostic (7.93e-3)" "unprognostic (1.12e-2)" "unprognostic (9.22e-3)" "unprognostic (3.26e-1)" "unprognostic (8.02e-2)" "unprognostic (7.84e-3)" "unprognostic (7.67e-3)" "unprognostic (4.38e-2)" "unprognostic (4.00e-1)" "unprognostic (9.55e-2)" "unprognostic (1.26e-2)" 20.6 11.4 11.9 11.0 13.5 19.2 25.5 15.5 16.6 14.6 13.1 15.0 6.5 12.8 16.8 13.4 12.7 12.9 12.9 11.4 12.6 11.6 12.1 17.5 13.9 10.0 12.8 11.6 16.7 11.4 13.1 9.1 102.6 14.1 14.2 12.2 32.1 13.2 12.1 17.0 16.6 16.0 18.6 12.7 11.3 12.5 17.9 13.0 17.5 14.5 9.3 11.5 15.9 14.8 12.6 8.3 21.9 5.2 5.3 6.1 3.5 8.4 7.6 16.6 14.9 14.3 12.5 17.0 7.9 10.8 11.8 5.8 5.8 11.1 11.0 8.8 10.0 9.9 11.4 11.6 14.6 4.4 9.2 5.9 6.0 15.1 20.0 5.8 9.1 15.0 20.9 6.9 16.1 9.9 9.5 10.5 9.6 5.8 15.6 11.9 20.2 11.8 18.2 25.0 11.6 11.0 10.7 18.9 16.8 23.6 11.8 20.3 7.5 13.4 10.5 12.7 11.4 6.8 8.4 13.7 5.7 20.2 9.4 7.2 11.4 6.9 5.2 21.9 2.7 2.2 3.0 12.6 3.0 4.2 8.3 12.1 6.1 4.5 2.9 5.3 1.3 7.9 1.6 3.5 11.9 13.5 15.5 16.6 12.6 11.6 12.8 11.6 14.1 13.0 SIAH2 ENSG00000181788 "Siah E3 ubiquitin protein ligase 2" O43255 3 150741127-150763477 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061293, CAB069930" Approved Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB069930: AB_1217916, HPA061293: " "prognostic favourable (1.17e-4)" "unprognostic (1.04e-3)" "unprognostic (3.83e-2)" "unprognostic (9.15e-2)" "unprognostic (1.69e-1)" "unprognostic (6.91e-2)" "unprognostic (1.86e-2)" "unprognostic (5.68e-3)" "unprognostic (6.26e-2)" "unprognostic (1.95e-2)" "prognostic unfavourable (8.21e-5)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-2)" "unprognostic (5.56e-1)" "unprognostic (1.66e-1)" "unprognostic (4.69e-2)" 9.6 48.0 7.6 11.8 10.3 22.7 23.5 10.9 17.2 30.0 10.5 8.4 20.3 7.9 23.5 13.9 28.8 14.9 11.0 10.7 7.2 7.3 8.4 35.5 11.8 19.1 9.9 7.5 19.0 14.6 6.4 8.1 31.4 7.9 18.8 9.2 8.3 11.2 21.7 8.3 19.3 9.5 17.4 9.4 16.9 12.0 8.7 8.6 23.6 11.4 10.6 25.1 22.7 25.6 3.0 3.1 10.0 2.7 1.6 3.6 1.1 16.6 4.1 3.2 6.4 11.1 8.4 13.1 6.9 8.0 8.4 10.3 8.4 7.5 9.3 10.2 7.2 10.3 8.7 6.2 7.9 7.8 6.2 18.2 5.0 27.9 15.9 10.0 5.4 7.6 14.5 5.0 11.5 6.5 4.5 36.7 5.3 20.0 18.3 5.1 10.5 8.2 13.5 7.0 33.3 5.3 5.8 12.5 5.9 5.2 4.9 12.3 32.9 15.1 4.5 5.8 5.2 12.6 9.3 43.7 16.6 13.0 5.5 14.5 2.9 9.5 2.7 10.0 2.1 1.5 3.2 2.5 3.6 3.2 2.4 3.0 1.9 1.9 5.9 1.6 1.5 3.1 2.0 1.1 7.6 10.3 10.9 17.2 7.2 7.3 9.9 7.5 7.9 8.6 SIK1 "msk, SNF1LK" ENSG00000142178 "Salt inducible kinase 1" P57059 21 43414483-43427189 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Cell cycle, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 34.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 16.7;HeLa: 27.8;hTCEpi: 21.5;LHCN-M2: 21.6;U-266/84: 15.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 2.0;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 10 "B-cells: 2.0;dendritic cells: 1.6" "CAB023801, HPA038211, HPA078064" Approved Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB023801: , HPA038211: , HPA078064: " "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (3.31e-3)" "unprognostic (3.00e-1)" "unprognostic (5.02e-2)" "unprognostic (7.97e-3)" "unprognostic (1.51e-1)" "unprognostic (7.30e-3)" "unprognostic (2.35e-3)" "unprognostic (4.97e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-1)" "unprognostic (3.89e-1)" "unprognostic (9.94e-3)" "unprognostic (3.88e-2)" "unprognostic (2.89e-1)" "unprognostic (1.82e-1)" 8.8 2.3 3.0 3.6 3.0 5.9 7.5 3.0 3.0 13.5 3.0 3.0 3.0 0.0 3.0 3.0 12.9 5.5 10.7 7.1 3.0 0.8 3.0 12.3 5.4 3.0 3.0 3.0 13.7 7.3 3.5 5.7 8.2 3.0 3.9 0.1 3.0 4.6 9.8 5.0 34.5 3.0 3.3 3.0 4.0 5.3 3.0 3.0 3.0 3.9 3.0 3.0 10.5 6.1 2.0 1.6 0.0 0.1 0.0 0.1 0.1 0.5 1.7 2.0 0.0 0.1 0.8 0.7 0.9 0.3 1.6 1.3 2.4 0.0 2.4 0.7 0.2 11.1 1.6 16.7 1.0 0.1 0.5 0.7 27.8 0.9 2.3 0.7 0.1 1.0 21.5 0.4 5.1 0.3 0.1 0.5 21.6 0.1 0.4 1.7 0.8 1.5 0.0 0.3 2.5 1.9 6.3 0.0 0.0 10.9 1.8 0.4 1.1 0.3 3.7 0.4 2.0 0.1 0.0 4.3 15.7 0.4 4.6 2.0 0.4 0.0 0.1 0.0 0.1 0.0 0.1 2.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 3.0 3.0 3.0 3.0 3.0 0.8 3.0 3.0 3.0 3.0 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602391-111730853 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016026 Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA016026: AB_1857321" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favourable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favourable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 32.8 10.7 10.1 6.6 17.2 4.0 22.5 10.6 17.3 10.0 9.9 15.1 5.2 7.7 9.5 7.0 7.9 9.7 12.7 14.5 10.5 10.3 14.6 24.4 13.6 5.4 9.7 9.9 16.4 37.8 22.0 28.6 7.5 11.9 8.4 8.3 14.9 15.4 8.6 35.1 8.7 7.7 8.7 9.6 5.8 19.6 4.2 13.0 4.4 11.1 7.9 5.8 8.6 10.0 2.2 2.7 2.8 3.6 2.2 3.5 2.1 5.8 3.9 6.8 7.3 34.0 10.1 4.0 5.1 7.3 3.9 4.5 13.1 6.2 4.6 7.1 5.9 8.3 5.3 3.8 5.1 3.4 2.2 5.0 3.4 6.4 7.4 4.8 3.3 9.8 5.7 5.7 7.4 4.6 4.6 6.7 6.1 2.7 5.0 4.4 2.3 3.9 6.7 7.3 5.5 8.7 5.3 3.2 7.5 7.5 3.1 3.0 7.5 3.9 6.4 8.6 5.2 5.5 7.0 1.9 1.5 9.7 2.8 6.8 5.8 1.1 3.3 2.8 3.5 3.6 1.9 2.0 2.5 2.5 2.7 2.2 1.4 2.0 1.4 2.2 2.9 1.5 2.4 2.1 10.1 17.2 10.6 16.4 10.5 10.3 9.7 9.9 11.9 13.0 SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236395 "Enzymes, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 168.1" "Cell line enhanced" "Detected in many" "A549: 18.9;HaCaT: 34.0;HeLa: 17.5;HL-60: 24.4;NB-4: 16.5;RT4: 17.3" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 27 "basophil: 27.3" "Lineage enriched" "Detected in many" 27 "granulocytes: 27.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 6 "hippocampal formation: 2.5" HPA026089 Enhanced "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favourable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favourable (6.40e-4)" 1.1 8.1 0.7 4.1 0.8 1.2 3.4 1.5 1.0 0.5 4.2 0.4 1.3 2.5 0.2 17.5 1.2 2.6 1.3 0.2 1.1 1.1 39.4 168.1 1.7 0.8 0.3 1.0 0.7 6.3 2.0 10.4 7.4 3.0 1.2 4.0 3.2 0.6 0.3 0.2 0.6 5.3 0.1 0.3 0.4 0.4 0.7 0.1 0.1 1.0 0.2 1.3 1.4 0.8 0.1 0.0 27.3 0.0 1.0 0.5 0.2 0.0 18.9 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.5 9.8 2.6 0.0 0.2 0.4 34.0 8.7 0.2 0.9 13.3 10.7 14.0 17.5 8.8 0.1 24.4 10.0 0.0 0.8 0.0 0.0 0.0 4.2 0.0 0.0 3.0 0.6 16.5 0.6 0.7 0.0 0.0 0.6 1.8 17.3 15.7 1.0 3.3 0.4 0.0 1.8 8.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 27.3 0.0 0.4 0.4 0.0 0.4 0.1 0.4 0.4 0.0 0.1 0.1 0.1 0.2 1.0 0.0 0.0 0.5 0.2 0.7 0.8 1.5 1.0 1.1 1.1 0.3 1.0 3.0 0.1 SLC27A5 "ACSB, ACSVL6, FACVL3, FATP5, FLJ22987, VLACSR, VLCS-H2, VLCSH2" ENSG00000083807 "Solute carrier family 27 member 5" Q9Y2P5 19 58479512-58512413 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Ligase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 157.6" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in all" 26 "liver cancer: 49.8" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA007292, CAB056160, CAB068239" Enhanced "CAB056160: , CAB068239: , HPA007292: AB_1857064" "unprognostic (5.97e-2)" "unprognostic (9.12e-2)" "unprognostic (9.95e-2)" "unprognostic (6.36e-3)" "unprognostic (2.52e-1)" "unprognostic (7.46e-2)" "prognostic favourable (1.57e-4)" "unprognostic (1.04e-1)" "unprognostic (1.85e-2)" "unprognostic (2.46e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.66e-4)" "unprognostic (2.27e-1)" "unprognostic (3.33e-2)" "unprognostic (7.80e-2)" "unprognostic (2.16e-1)" 1.3 2.0 5.4 1.4 5.3 1.1 2.0 1.9 3.9 1.7 1.0 1.7 1.2 1.0 1.1 1.1 1.4 2.6 1.1 1.3 3.7 3.8 1.9 157.6 0.9 1.4 4.3 2.5 1.4 2.6 1.1 1.3 0.8 3.4 1.4 0.8 1.3 2.7 2.1 1.4 1.1 0.9 1.5 2.7 1.1 1.1 2.3 3.0 1.4 1.8 0.6 1.4 1.1 1.6 13.3 10.8 2.2 3.0 9.6 18.7 8.9 15.9 21.8 3.9 4.1 3.7 3.9 2.4 0.9 2.1 3.0 4.2 1.7 3.4 20.7 2.6 1.1 3.3 4.4 14.0 1.3 9.6 14.7 13.9 22.7 18.1 5.6 7.3 4.9 4.5 2.4 0.4 8.4 1.5 12.8 0.0 3.6 13.0 17.9 15.4 2.3 12.8 9.1 0.1 28.2 10.0 7.6 5.3 7.3 0.0 21.6 4.7 6.4 6.3 1.2 0.0 2.8 0.0 1.8 13.6 15.3 8.4 4.5 13.6 0.8 0.0 2.4 2.2 8.7 3.0 18.7 13.3 11.2 11.4 6.5 8.9 13.9 14.3 0.3 9.6 2.1 10.8 13.3 8.9 5.4 5.3 1.9 3.9 3.7 3.8 4.3 2.5 3.4 3.0 SLK "KIAA0204, se20-9, STK2" ENSG00000065613 "STE20 like kinase" Q9H2G2 10 103967201-104029233 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015757 Approved Approved "Plasma membrane,Cytosol" 17000 "Plasma membrane, Cytosol" "HPA015757: AB_1857236" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (8.67e-2)" "unprognostic (6.85e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "prognostic unfavourable (2.77e-5)" "unprognostic (1.95e-1)" "prognostic favourable (3.95e-5)" "unprognostic (8.48e-2)" "unprognostic (3.95e-1)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" 15.2 11.2 13.7 11.0 36.7 14.6 16.1 16.7 13.1 16.6 19.0 9.9 10.9 9.1 17.0 12.1 40.2 12.1 13.6 17.2 10.6 7.1 14.9 12.2 17.1 10.1 11.2 13.4 17.2 12.5 22.6 13.1 17.4 12.8 19.3 13.6 11.4 19.8 12.7 19.3 16.6 15.5 29.8 13.0 12.1 15.7 10.2 12.8 12.0 15.8 21.6 12.5 24.9 23.6 1.4 2.2 6.5 1.4 1.3 3.6 0.7 21.2 12.4 14.9 10.6 16.1 22.5 6.3 13.3 17.7 9.9 9.3 7.9 22.9 11.3 8.3 13.7 23.2 7.8 16.8 14.5 9.0 10.8 11.5 10.2 6.6 12.1 13.7 10.0 11.5 22.1 13.4 39.2 17.8 14.3 7.8 13.0 7.4 9.6 7.6 3.7 8.0 9.4 18.3 5.8 13.0 24.5 3.5 6.1 11.5 11.2 11.0 5.8 9.9 26.9 7.3 7.6 13.4 15.5 9.5 11.6 7.2 10.8 18.4 4.7 1.2 1.4 3.3 3.6 1.2 3.6 1.1 2.2 2.2 1.2 1.4 1.5 2.5 6.5 1.3 1.0 2.2 1.4 0.7 13.7 36.7 16.7 13.1 10.6 7.1 11.2 13.4 12.8 12.8 SMARCAD1 "DKFZP762K2015, ETL1, KIAA1122" ENSG00000163104 "SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1" Q9H4L7 4 94207611-94291292 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016737 Approved Enhanced Nucleoplasm Nucleoplasm "HPA016737: AB_1857271" "unprognostic (5.01e-2)" "unprognostic (5.83e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (8.41e-3)" "unprognostic (9.08e-3)" "prognostic unfavourable (3.22e-5)" "unprognostic (2.45e-1)" "unprognostic (3.49e-3)" "unprognostic (3.55e-1)" "unprognostic (2.57e-2)" "unprognostic (7.72e-2)" "unprognostic (2.99e-2)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (3.20e-3)" 12.8 15.4 15.4 22.2 14.6 8.6 20.1 26.7 25.1 15.4 13.6 9.4 14.4 12.6 19.6 17.5 17.2 16.5 13.9 12.9 13.6 14.7 16.6 14.9 21.6 22.8 17.6 11.1 20.8 15.0 17.2 33.0 18.3 14.9 15.4 16.5 10.2 14.9 20.9 11.8 26.5 13.9 15.6 17.9 17.6 13.9 15.3 16.2 42.0 20.2 11.4 17.8 16.0 15.9 5.5 4.3 3.5 3.0 7.5 6.2 2.7 7.3 9.6 29.7 19.4 8.6 14.1 15.4 13.1 12.3 11.0 10.5 8.5 12.0 18.9 9.1 11.2 6.4 20.9 11.1 15.9 14.4 9.5 13.6 10.3 13.1 12.4 19.8 14.6 14.4 9.1 13.6 17.6 17.0 22.4 7.9 16.6 5.8 33.6 10.5 20.6 4.7 19.6 17.0 9.6 12.8 9.0 17.5 25.8 10.1 17.0 14.4 8.7 13.4 16.1 14.3 15.3 8.7 10.0 11.1 16.7 22.7 13.4 10.6 17.6 3.5 2.5 0.3 4.6 3.0 4.8 5.5 5.1 4.9 4.3 4.2 5.5 6.2 0.0 7.5 2.9 3.7 4.1 2.7 15.4 14.6 26.7 25.1 13.6 14.7 17.6 11.1 14.9 16.2 SMG1 "ATX, KIAA0421, LIP" ENSG00000157106 "SMG1, nonsense mediated mRNA decay associated PI3K related kinase" Q96Q15 16 18804853-18926454 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Nonsense-mediated mRNA decay" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006870, HPA031623, HPA073972" Approved Supported Nucleoplasm Nucleoplasm "HPA006870: AB_1079725, HPA031623: , HPA073972: " "unprognostic (6.34e-2)" "unprognostic (5.88e-2)" "unprognostic (5.98e-2)" "unprognostic (2.66e-1)" "unprognostic (2.44e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (8.32e-3)" "unprognostic (7.28e-2)" "unprognostic (1.05e-1)" "unprognostic (2.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" 4.7 3.0 2.1 4.5 3.5 11.7 6.2 13.2 3.0 4.4 4.5 3.1 5.4 5.1 5.5 4.0 3.0 4.5 2.3 2.2 4.6 5.4 4.1 6.2 2.3 6.3 4.5 7.2 3.9 3.1 4.2 5.0 4.7 3.3 21.1 14.4 5.0 3.9 3.4 4.5 4.3 4.0 6.0 5.8 5.2 4.9 7.1 4.6 19.1 5.6 2.3 6.1 1.0 23.2 15.6 14.7 10.4 16.9 17.9 10.9 10.9 10.7 11.9 13.3 13.7 8.6 32.1 15.7 15.1 13.3 16.9 9.5 19.0 20.6 10.6 14.6 13.7 17.5 13.7 19.6 11.6 10.5 16.1 24.5 29.6 16.6 22.4 17.9 13.1 12.4 13.5 11.8 15.7 9.0 15.7 19.8 11.0 10.2 18.3 13.4 10.2 16.9 11.5 11.9 9.2 12.5 21.0 17.9 12.0 11.0 16.1 9.2 11.9 21.2 11.9 15.3 10.6 19.1 2.5 3.4 6.1 2.8 2.9 3.7 4.0 4.3 2.5 7.1 5.4 4.7 7.6 2.3 5.6 4.6 3.7 1.0 SMOX "C20orf16, dJ779E11.1, FLJ20746, MGC1010, PAO, PAOh1, SMO" ENSG00000088826 "Spermine oxidase" Q9NWM0 20 4120980-4187747 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 34.7;Karpas-707: 59.3;RPTEC TERT1: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "myeloid DC: 2.1;neutrophil: 3.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047117, HPA060198" Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Nuclear membrane" "Nucleoplasm, Vesicles" "HPA047117: , HPA060198: " "unprognostic (1.24e-2)" "unprognostic (6.55e-2)" "unprognostic (7.24e-3)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" "unprognostic (2.32e-1)" "prognostic unfavourable (3.33e-6)" "prognostic unfavourable (1.36e-4)" "unprognostic (4.92e-2)" "unprognostic (3.37e-1)" "unprognostic (7.18e-2)" "unprognostic (7.58e-2)" "prognostic unfavourable (1.06e-4)" "unprognostic (4.08e-2)" "unprognostic (2.64e-3)" "unprognostic (1.26e-2)" "unprognostic (3.07e-1)" 3.5 3.1 26.0 4.1 22.7 24.2 3.4 10.1 29.0 9.6 6.7 23.5 17.6 9.5 10.2 6.9 6.1 4.7 14.0 2.9 28.8 16.2 3.8 4.4 2.1 4.0 25.1 16.5 9.2 28.9 8.7 6.0 5.7 20.7 8.1 1.4 6.5 10.6 10.2 2.5 7.8 7.1 3.9 25.9 2.9 7.4 3.9 24.1 0.3 3.9 3.4 2.6 5.3 5.2 0.1 2.1 3.5 0.9 0.2 0.2 15.3 3.1 34.7 2.4 1.8 1.7 2.5 4.4 4.5 8.7 3.3 2.2 14.2 8.7 0.0 1.5 4.1 6.3 2.0 2.1 1.4 0.0 1.0 6.1 1.1 14.4 10.7 1.1 2.5 9.6 3.9 6.9 2.9 5.8 1.3 59.3 1.9 0.9 2.3 3.4 3.0 4.7 2.0 3.0 8.2 27.3 2.4 0.4 2.1 8.4 0.9 15.6 0.1 1.5 6.9 3.8 3.6 0.6 3.5 2.7 0.4 0.0 3.2 1.5 2.9 0.0 0.9 0.1 0.0 0.4 0.0 0.1 0.2 0.2 2.1 0.0 0.0 0.0 3.5 0.2 0.1 1.0 0.0 15.3 26.0 22.7 10.1 17.6 28.8 16.2 25.1 16.5 20.7 24.1 SMPD2 "ISC1, nSMase" ENSG00000135587 "Sphingomyelin phosphodiesterase 2" O60906 6 109440763-109443919 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA018110, HPA018125" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" "Vesicles, Plasma membrane" "Cell Junctions" "HPA018110: AB_1857292, HPA018125: AB_1857293" "unprognostic (1.61e-1)" "unprognostic (8.01e-2)" "unprognostic (1.97e-1)" "unprognostic (8.79e-3)" "unprognostic (3.88e-2)" "unprognostic (2.38e-1)" "prognostic unfavourable (1.17e-4)" "unprognostic (7.08e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" "prognostic favourable (1.00e-3)" "unprognostic (3.60e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" "unprognostic (1.45e-2)" "prognostic favourable (1.70e-4)" 6.0 6.8 4.2 20.2 4.9 8.5 8.5 5.4 6.4 9.0 12.6 9.8 16.4 10.5 6.1 16.0 17.2 17.4 12.6 5.1 4.9 3.7 10.2 7.8 8.4 9.4 4.7 4.2 6.7 15.5 17.9 8.8 19.5 4.8 10.1 10.2 8.4 16.6 11.9 3.3 16.9 15.4 7.8 4.3 10.1 11.1 35.1 4.7 18.3 10.5 13.5 23.0 6.3 10.1 18.3 13.4 9.3 7.8 6.2 8.0 5.3 8.9 10.4 5.5 8.6 9.6 5.3 18.3 3.0 11.1 7.5 7.2 9.7 7.3 4.9 6.4 6.4 11.5 5.5 13.2 4.5 6.2 14.2 5.7 10.7 6.0 8.1 6.2 6.7 5.6 15.3 6.7 13.3 6.9 10.9 8.7 3.7 12.9 10.0 13.5 1.5 5.0 7.0 2.6 5.3 13.7 15.3 7.2 6.0 5.7 17.8 13.4 5.7 11.9 4.4 3.4 4.9 2.7 11.2 5.9 1.5 3.1 6.6 5.9 6.0 5.7 7.8 9.3 6.6 7.5 7.3 12.8 7.4 8.0 10.2 18.3 5.6 5.7 2.3 6.2 6.6 13.4 7.2 5.3 4.2 4.9 5.4 6.4 4.9 3.7 4.7 4.2 4.8 4.7 SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358325-68448688 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 44.5;intestine: 46.4;lymphoid tissue: 73.0" "Cell line enhanced" "Detected in some" "HMC-1: 9.4;MOLT-4: 13.4;RPMI-8226: 11.1;SCLC-21H: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 7 "plasmacytoid DC: 44.5" "Lineage enriched" "Detected in many" 7 "dendritic cells: 44.5" "Region enhanced" "Detected in many" "basal ganglia: 103.1" "Low region specificity" "Detected in all" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favourable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favourable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" 3.5 2.3 6.0 3.1 18.3 1.8 1.6 9.4 15.4 1.0 9.6 2.5 0.0 46.4 1.7 0.7 1.8 2.7 17.2 1.2 8.7 3.6 0.9 3.8 2.1 3.5 2.5 5.0 2.7 1.9 0.7 10.7 0.8 3.9 2.2 5.8 4.3 2.2 0.9 1.8 8.1 42.7 1.2 1.4 3.0 18.6 4.2 4.4 73.0 1.3 1.3 4.3 1.6 1.2 0.6 44.5 6.1 0.0 0.0 0.7 0.3 0.3 0.7 0.3 0.1 0.0 0.0 5.2 0.4 0.0 0.4 0.1 2.9 0.9 0.4 0.5 0.2 1.1 0.0 0.0 0.1 0.3 0.7 0.1 2.1 0.3 0.0 0.0 9.4 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.3 0.2 13.4 2.5 0.6 0.1 0.6 0.2 11.1 0.0 0.1 12.9 2.5 0.4 1.5 0.6 1.0 0.8 0.0 0.4 0.8 1.4 0.1 2.1 1.1 0.2 0.2 0.8 0.2 1.0 0.0 6.1 0.7 0.0 0.1 0.6 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 44.5 0.5 0.3 6.0 18.3 9.4 15.4 8.7 3.6 2.5 5.0 3.9 4.4 SMPD4 "FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3" ENSG00000136699 "Sphingomyelin phosphodiesterase 4" Q9NXE4 2 130151392-130182750 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046279, HPA049426" Approved Approved "Nuclear membrane,Cytosol" "Nuclear membrane" Cytosol "HPA046279: , HPA049426: " "unprognostic (5.02e-2)" "unprognostic (9.61e-3)" "unprognostic (6.31e-2)" "prognostic unfavourable (7.47e-5)" "unprognostic (1.69e-1)" "unprognostic (8.80e-2)" "prognostic unfavourable (8.37e-6)" "unprognostic (3.27e-2)" "unprognostic (1.72e-1)" "unprognostic (7.47e-2)" "unprognostic (1.49e-2)" "prognostic unfavourable (1.73e-4)" "prognostic unfavourable (8.16e-8)" "unprognostic (1.74e-1)" "unprognostic (2.28e-1)" "unprognostic (1.47e-3)" "unprognostic (2.09e-1)" 13.2 16.1 12.4 17.1 20.7 39.1 14.8 22.1 25.1 19.9 15.8 31.4 15.3 15.5 22.5 14.1 19.3 19.5 12.7 13.4 13.2 16.0 14.3 18.5 14.7 20.5 21.3 12.2 22.2 22.2 24.1 31.2 24.3 19.5 16.3 16.7 17.7 17.1 15.2 17.0 17.5 15.2 18.3 16.0 16.4 14.5 23.6 21.6 27.9 22.8 19.6 27.1 16.9 16.6 10.5 9.8 14.5 11.4 11.7 15.2 9.7 31.7 15.7 19.8 14.6 10.2 7.5 25.8 16.9 12.6 25.0 20.9 45.4 16.3 20.7 15.0 17.0 18.1 25.3 22.4 17.4 27.4 24.4 23.3 16.9 36.0 8.7 26.0 14.9 8.8 15.0 28.0 11.2 14.4 28.9 16.8 13.9 17.2 27.1 13.1 30.4 20.9 28.8 15.1 22.5 10.6 15.1 27.6 15.4 16.7 20.4 7.4 13.9 11.4 11.1 21.4 20.8 14.0 19.8 14.7 16.4 27.8 19.3 14.9 15.2 1.8 9.3 14.5 13.9 11.4 15.2 9.5 10.4 12.4 9.8 10.5 10.2 11.4 4.5 11.7 8.0 6.4 9.4 9.7 12.4 20.7 22.1 25.1 13.2 16.0 21.3 12.2 19.5 21.6 SMS "MRSR, SPMSY, SpS, SRS" ENSG00000102172 "Spermine synthase" P52788 X 21940573-21994835 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Polyamine biosynthesis" Transferase "FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029849, HPA029852" Approved Approved "Nuclear bodies,Cytosol" 26000 "Nuclear bodies" Cytosol "HPA029849: AB_10602072, HPA029852: AB_10611521" "unprognostic (2.51e-2)" "unprognostic (2.91e-1)" "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "prognostic unfavourable (7.49e-4)" "prognostic unfavourable (7.79e-8)" "unprognostic (1.02e-2)" "unprognostic (2.72e-1)" "unprognostic (3.18e-3)" "unprognostic (3.95e-3)" "unprognostic (2.45e-1)" "prognostic unfavourable (7.85e-5)" "unprognostic (2.70e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" "unprognostic (8.50e-2)" 21.7 48.1 29.7 18.7 25.0 18.6 28.4 36.6 35.4 20.8 23.1 8.1 26.0 23.5 20.8 31.3 19.2 13.3 20.9 26.3 22.3 25.0 55.1 19.5 17.6 18.5 25.6 28.5 42.4 16.7 13.6 19.2 63.6 24.2 61.3 24.4 15.7 20.7 20.6 18.0 9.7 25.1 36.8 17.4 18.9 18.8 18.4 11.0 19.6 27.6 11.7 20.8 28.2 16.5 13.2 19.4 37.0 25.7 11.7 20.3 12.3 90.6 23.2 39.6 15.0 10.5 17.8 12.3 24.9 14.9 38.3 36.7 28.8 29.7 32.9 8.6 25.4 19.9 38.7 45.4 75.8 15.2 18.1 17.0 28.0 20.4 19.3 32.9 15.0 11.7 13.9 39.3 73.9 36.6 36.2 4.6 52.1 19.3 24.3 33.0 67.1 34.5 24.3 27.2 25.0 51.0 12.9 18.9 15.3 19.9 25.6 65.5 23.1 13.7 32.3 27.8 28.0 57.6 40.4 3.5 7.0 19.6 54.2 14.7 38.5 2.9 21.4 37.0 7.6 22.1 9.4 13.2 12.0 13.2 19.4 8.3 7.9 9.3 21.1 11.7 25.7 4.0 20.3 12.3 29.7 25.0 36.6 35.4 22.3 25.0 25.6 28.5 24.2 11.0 SMURF1 KIAA1625 ENSG00000198742 "SMAD specific E3 ubiquitin protein ligase 1" Q9HCE7 7 99027438-99144100 "Enzymes, Predicted intracellular proteins" "Differentiation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019671, HPA055245" Approved Uncertain Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA019671: , HPA055245: " "unprognostic (2.21e-1)" "unprognostic (6.15e-2)" "unprognostic (8.88e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" "unprognostic (2.15e-2)" "unprognostic (3.92e-3)" "unprognostic (2.58e-1)" "unprognostic (1.46e-1)" "unprognostic (7.83e-2)" "unprognostic (1.68e-1)" "unprognostic (3.81e-1)" "unprognostic (4.62e-2)" 15.0 11.1 8.7 10.5 15.0 23.8 12.4 12.1 16.5 11.8 10.9 20.9 6.9 9.5 11.6 5.7 19.3 10.2 12.5 7.9 9.3 8.4 10.3 10.1 16.0 8.1 15.4 9.4 19.6 22.5 9.0 15.1 15.4 14.9 11.7 10.6 14.3 13.4 9.6 10.7 17.3 10.3 9.8 10.6 9.1 19.5 26.0 11.8 6.6 7.8 6.6 12.7 11.5 13.3 1.2 1.2 2.4 1.9 1.0 2.1 0.6 13.8 7.9 6.4 4.6 5.1 5.4 9.6 7.8 7.5 6.3 5.9 4.0 11.5 4.3 8.4 7.2 7.6 3.6 10.0 6.6 3.3 3.0 2.3 4.6 3.8 4.8 2.6 5.7 4.9 7.0 9.9 11.5 6.0 7.0 7.7 5.8 11.2 4.5 5.5 7.5 8.5 4.3 6.0 2.6 6.9 11.4 2.8 6.4 7.4 9.8 6.8 3.1 5.0 8.7 10.0 10.3 17.9 15.4 6.9 4.7 4.6 5.0 5.2 15.5 2.0 1.4 2.3 1.3 1.5 1.6 0.9 2.1 1.3 1.1 1.2 1.2 1.0 2.4 1.0 1.9 1.2 2.0 0.6 8.7 15.0 12.1 16.5 9.3 8.4 15.4 9.4 14.9 11.8 SMURF2 ENSG00000108854 "SMAD specific E3 ubiquitin protein ligase 2" Q9HAU4 17 64542295-64662068 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 54.0;HBF TERT88: 41.5;LHCN-M2: 41.5;TIME: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071508 Enhanced Supported "Nuclear speckles" "Nuclear speckles" "HPA071508: " "unprognostic (1.21e-1)" "unprognostic (2.07e-2)" "unprognostic (1.59e-2)" "unprognostic (3.24e-1)" "unprognostic (6.19e-2)" "unprognostic (7.33e-2)" "unprognostic (2.67e-2)" "unprognostic (1.50e-1)" "unprognostic (7.94e-2)" "unprognostic (1.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.54e-1)" "unprognostic (5.55e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" 12.3 9.2 10.5 9.0 15.0 11.5 10.2 16.7 10.0 9.2 9.1 11.5 8.1 9.3 7.9 6.9 7.6 7.8 10.5 8.2 12.6 4.6 9.4 5.7 19.0 8.6 9.5 4.8 8.5 9.0 8.2 10.7 15.3 10.1 10.6 8.2 9.6 9.9 7.6 7.5 11.0 13.7 8.9 6.6 9.9 9.8 21.6 10.6 8.9 11.4 4.1 9.6 9.4 11.7 3.0 3.0 4.8 2.2 7.3 3.5 1.7 15.6 4.3 3.7 2.8 2.6 10.0 1.8 54.0 24.6 21.1 18.4 2.4 12.0 2.1 3.4 9.2 3.5 3.5 9.3 41.5 1.1 2.3 2.2 2.6 2.9 2.3 2.9 1.4 2.7 3.6 29.3 11.2 24.3 3.2 2.1 41.5 3.4 6.7 1.3 2.2 5.7 1.5 9.0 1.3 5.8 2.8 3.5 3.1 3.3 1.7 2.5 2.8 2.3 47.8 24.0 13.0 9.2 35.8 2.4 2.8 3.8 5.9 1.7 7.2 2.8 2.2 4.8 3.3 2.0 2.8 2.0 2.4 3.5 3.0 3.0 2.3 2.6 4.4 7.3 1.0 2.6 1.1 1.7 10.5 15.0 16.7 10.0 12.6 4.6 9.5 4.8 10.1 10.6 SMYD1 "BOP, KMT3D, ZMYND22" ENSG00000115593 "SET and MYND domain containing 1" Q8NB12 2 88067780-88113387 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 45.9;skeletal muscle: 103.7;tongue: 36.4" "Cell line enriched" "Detected in some" 5 "HSkMC: 5.5" "Cancer enhanced" "Detected in some" "stomach cancer: 1.6" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA062282 Enhanced "HPA062282: " "unprognostic (1.93e-2)" "unprognostic (2.49e-1)" "unprognostic (4.09e-2)" "unprognostic (8.51e-3)" "unprognostic (2.74e-1)" "unprognostic (3.91e-1)" "unprognostic (8.81e-3)" "unprognostic (1.40e-1)" 2.7 0.0 0.1 0.1 0.3 0.0 1.2 0.0 1.4 0.0 4.6 0.0 0.0 0.4 0.0 3.4 2.5 0.0 0.2 45.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.4 0.0 1.5 0.0 103.7 0.0 4.4 6.3 0.1 0.0 2.6 0.1 0.0 0.0 0.2 36.4 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 1.4 0.1 0.0 0.1 0.1 0.0 0.0 SMYD2 "HSKM-B, KMT3C, ZMYND14" ENSG00000143499 "SET and MYND domain containing 2" Q9NRG4 1 214281102-214337131 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 75.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029023 Uncertain Approved "Intermediate filaments,Mitochondria,Cytosol" Cytosol "Intermediate filaments, Mitochondria" "HPA029023: AB_10601605" "unprognostic (8.53e-2)" "prognostic unfavourable (1.53e-5)" "unprognostic (5.98e-2)" "unprognostic (1.00e-2)" "unprognostic (8.55e-2)" "unprognostic (2.53e-2)" "unprognostic (2.24e-2)" "unprognostic (1.72e-2)" "unprognostic (1.90e-3)" "unprognostic (1.65e-1)" "unprognostic (9.44e-2)" "unprognostic (2.77e-1)" "prognostic favourable (8.68e-4)" "unprognostic (2.65e-1)" "unprognostic (4.92e-2)" "unprognostic (8.10e-2)" "unprognostic (6.37e-2)" 5.9 5.7 8.8 5.6 7.3 2.7 10.0 5.0 23.9 4.9 4.7 2.1 3.1 4.8 3.8 6.7 7.3 10.4 4.5 75.7 7.0 8.4 7.7 9.7 8.1 8.0 5.3 10.0 4.7 7.8 2.9 7.5 10.6 6.9 4.6 5.8 3.1 6.2 3.0 29.5 4.3 4.7 3.8 4.7 6.2 6.2 8.9 2.2 8.0 7.8 5.1 5.6 5.2 4.0 9.3 5.5 8.1 5.9 17.6 14.5 7.3 24.1 7.0 9.5 6.7 9.9 17.2 40.6 13.6 11.3 17.3 19.7 27.5 20.7 12.5 14.1 15.4 11.4 9.0 25.4 16.8 10.4 10.5 4.0 11.8 21.9 8.9 17.6 2.8 18.4 14.3 12.0 9.6 12.5 12.7 3.2 15.5 12.6 12.2 11.1 8.6 9.5 7.6 23.1 10.6 17.1 17.7 9.4 22.0 10.6 38.3 28.2 29.8 11.7 14.4 13.5 19.9 7.4 21.1 12.9 4.8 14.4 17.5 14.0 15.3 6.7 5.9 8.1 9.5 3.2 11.2 9.3 14.5 12.7 5.5 4.8 12.7 11.6 0.6 17.6 1.2 3.8 14.5 7.3 8.8 7.3 5.0 23.9 7.0 8.4 5.3 10.0 6.9 2.2 SMYD3 "KMT3E, ZMYND1, ZNFN3A1" ENSG00000185420 "SET and MYND domain containing 3" Q9H7B4 1 245749342-246507312 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 92.9;K-562: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012229, HPA045821, HPA054352" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB012229: , HPA045821: , HPA054352: " "unprognostic (7.00e-3)" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (6.18e-3)" "unprognostic (3.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.25e-3)" "unprognostic (1.72e-3)" "unprognostic (4.53e-2)" "unprognostic (1.57e-1)" "unprognostic (1.71e-1)" "unprognostic (2.10e-1)" "unprognostic (3.78e-5)" "unprognostic (9.03e-3)" "unprognostic (2.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.58e-1)" 6.0 12.0 9.9 9.7 16.2 7.6 10.6 25.9 14.7 8.9 6.5 6.4 3.7 4.5 8.7 21.8 6.1 10.0 7.7 5.8 10.3 12.0 8.9 5.5 9.2 6.3 12.0 10.2 8.0 7.2 6.7 11.9 4.6 15.3 6.8 8.3 9.5 5.3 5.9 9.5 6.7 5.2 7.6 6.8 5.3 6.1 10.5 8.1 7.5 18.8 3.6 9.3 8.3 6.6 11.3 5.9 8.3 3.4 19.4 12.9 8.7 4.6 2.8 4.1 3.5 4.7 6.4 4.1 6.5 4.9 7.7 17.3 3.7 5.4 7.6 5.3 6.0 3.0 3.7 7.3 25.9 4.0 3.8 4.4 4.2 4.4 8.8 4.4 92.9 17.3 1.7 10.2 6.6 5.2 35.1 2.6 7.5 1.6 8.5 8.6 3.7 4.5 7.9 5.0 10.9 5.6 6.8 9.8 4.7 3.1 0.4 5.9 3.8 7.6 4.0 3.7 2.6 2.6 7.7 13.3 3.6 3.9 7.1 6.1 4.3 8.1 3.4 8.3 10.5 3.0 10.8 11.3 11.1 12.8 5.9 11.1 12.3 12.9 2.4 19.4 3.3 3.8 11.8 8.7 9.9 16.2 25.9 14.7 10.3 12.0 12.0 10.2 15.3 8.1 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 50.8;TIME: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favourable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favourable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 31.5 8.8 9.8 13.1 14.4 41.0 22.6 34.5 21.1 17.6 14.4 7.9 5.9 12.8 20.9 10.5 16.2 11.5 16.4 13.9 11.0 11.0 16.8 20.3 24.7 19.8 11.4 10.6 15.1 18.0 18.4 16.2 26.2 22.5 12.1 9.9 14.7 10.7 9.4 12.5 24.5 17.0 18.7 9.8 25.4 11.2 13.9 7.2 48.4 24.8 13.5 14.4 15.8 19.3 3.2 3.0 20.9 5.5 8.1 10.7 6.5 3.2 2.0 3.7 3.5 11.1 4.0 3.5 3.5 5.9 3.8 3.8 2.7 4.7 5.1 2.8 4.4 2.1 4.3 7.5 4.0 5.9 3.5 5.9 3.7 3.1 5.8 6.6 6.6 4.4 5.2 4.3 7.4 50.8 2.6 6.0 3.5 1.7 6.6 5.8 4.1 9.1 4.6 2.7 5.4 9.9 5.6 2.6 5.5 3.0 3.3 4.2 2.2 8.4 29.5 3.4 3.4 3.9 4.1 9.7 6.9 4.4 2.4 7.9 4.8 4.8 2.8 5.4 7.6 5.5 10.7 2.8 6.7 7.6 3.0 3.2 10.1 10.1 20.9 8.1 5.0 0.9 7.1 6.5 9.8 14.4 34.5 21.1 11.0 11.0 11.4 10.6 22.5 7.2 SNRNP200 "ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD" ENSG00000144028 "Small nuclear ribonucleoprotein U5 subunit 200" O75643 2 96274336-96305515 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029321 Approved Supported Nucleoplasm 6600 Nucleoplasm "HPA029321: AB_10604096" "unprognostic (2.63e-2)" "unprognostic (1.45e-1)" "unprognostic (1.44e-1)" "prognostic unfavourable (3.89e-4)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (2.48e-3)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "unprognostic (6.46e-2)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (2.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" 26.6 25.2 18.4 28.4 21.9 32.0 26.1 37.2 25.8 24.4 23.6 23.7 20.6 18.4 34.7 22.6 23.4 26.5 22.0 22.0 19.7 12.3 19.0 25.8 22.7 25.1 16.6 18.9 39.3 22.7 49.4 25.2 33.7 18.9 21.3 22.0 25.5 28.3 23.0 39.7 25.3 27.6 28.3 15.8 25.2 23.4 34.3 19.5 57.3 25.3 21.3 31.2 33.7 24.0 8.5 7.7 15.3 7.5 9.1 12.6 6.0 23.1 26.3 35.3 26.5 16.5 14.6 33.2 16.0 19.6 29.3 28.1 47.8 17.0 40.3 25.4 20.4 18.4 64.8 21.8 30.4 21.8 34.2 51.6 41.9 25.9 10.7 39.5 22.7 15.1 13.6 33.3 28.4 23.8 45.1 27.2 16.9 20.2 37.0 11.8 46.0 25.5 43.7 34.3 25.3 11.4 34.2 39.2 37.4 26.0 22.3 16.6 21.2 24.7 20.6 24.5 29.7 24.8 23.0 25.3 29.8 50.3 16.5 26.4 26.1 15.3 5.6 7.5 10.1 7.0 12.2 7.8 7.8 12.6 7.3 8.5 7.6 9.3 6.2 9.1 7.5 7.7 8.5 6.0 18.4 21.9 37.2 25.8 19.7 12.3 16.6 18.9 18.9 19.5 SOAT1 "ACAT, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 87.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB009533: AB_633499, HPA047171: " "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.81e-3)" "unprognostic (7.81e-3)" "unprognostic (3.29e-1)" "unprognostic (9.00e-2)" "unprognostic (9.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.45e-3)" "unprognostic (7.02e-3)" "unprognostic (4.67e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-2)" "unprognostic (1.82e-1)" 23.9 87.4 4.1 8.3 5.7 7.0 9.6 2.9 4.0 6.8 7.2 5.6 7.8 5.5 8.2 6.0 3.4 8.3 9.8 5.7 5.5 4.1 12.1 8.8 18.6 13.0 6.2 2.3 10.8 15.5 8.1 14.6 11.6 4.9 13.1 6.9 9.6 51.1 8.9 4.1 5.8 7.0 7.5 10.5 13.6 8.1 6.8 4.9 4.0 6.2 2.9 7.2 9.4 8.7 6.6 24.3 19.8 26.8 18.5 16.0 14.8 20.2 9.5 7.8 11.6 30.5 16.7 42.0 9.8 17.3 21.7 25.5 9.7 23.2 11.5 15.5 17.8 7.5 24.9 5.8 23.5 13.1 5.1 5.3 8.0 10.1 12.5 9.1 2.1 13.2 3.8 25.4 21.8 9.3 11.4 5.9 33.8 4.3 9.6 2.9 3.8 3.1 12.1 10.1 6.7 19.2 12.7 2.4 6.1 15.1 6.4 5.6 6.7 6.3 8.8 25.9 12.4 28.3 21.5 8.4 30.6 9.8 10.3 4.9 48.0 19.6 26.8 0.7 14.0 17.0 13.5 6.6 13.1 13.1 24.3 5.5 12.7 12.6 19.8 18.5 11.1 4.4 16.0 14.8 4.1 5.7 2.9 4.0 5.5 4.1 6.2 2.3 4.9 4.9 SOD1 "ALS, ALS1, IPOA" ENSG00000142168 "Superoxide dismutase 1" P00441 21 31659622-31668931 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 282.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001401, CAB008670" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" 91000000 "Nucleoplasm, Plasma membrane, Cytosol" "CAB008670: AB_1623312, HPA001401: AB_1080132" "unprognostic (1.73e-1)" "unprognostic (1.18e-2)" "unprognostic (4.43e-1)" "unprognostic (6.19e-2)" "unprognostic (1.39e-1)" "unprognostic (9.59e-3)" "unprognostic (8.34e-2)" "unprognostic (2.30e-1)" "unprognostic (3.47e-1)" "unprognostic (5.28e-2)" "unprognostic (9.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-2)" "unprognostic (1.57e-1)" "unprognostic (3.26e-2)" 39.2 86.5 71.1 29.1 74.3 24.6 108.6 35.6 74.9 26.8 37.7 19.1 35.4 62.5 24.6 42.2 25.8 36.0 46.8 96.5 77.8 73.1 84.0 282.6 23.0 26.8 80.2 67.0 53.9 27.2 27.1 30.4 29.7 96.1 35.1 32.6 19.3 19.7 39.3 83.9 20.5 45.5 45.2 88.2 19.2 25.8 22.2 43.8 12.3 30.1 34.7 25.6 25.4 124.0 57.6 32.3 24.9 57.2 29.6 95.6 55.6 55.6 48.7 34.2 34.2 45.8 31.9 28.4 47.0 28.1 32.0 24.2 63.1 35.4 66.7 49.5 43.3 20.2 49.0 34.6 26.4 49.2 60.9 107.6 63.9 90.2 30.3 47.5 40.3 33.1 26.4 44.8 24.9 35.9 74.2 85.3 38.5 90.4 51.0 47.9 51.4 52.0 43.9 69.0 103.7 62.5 34.2 37.4 31.4 87.1 46.1 45.2 53.0 42.0 42.0 24.9 55.1 33.6 34.6 65.2 141.0 79.0 50.8 69.3 33.0 22.1 21.9 24.9 45.0 30.2 51.6 57.6 73.1 56.9 28.6 40.9 76.2 59.3 5.1 29.6 57.2 32.3 95.6 55.6 71.1 74.3 35.6 74.9 77.8 73.1 80.2 67.0 96.1 43.8 SOD3 EC-SOD ENSG00000109610 "Superoxide dismutase 3" P08294 4 24789912-24800842 "Enzymes, Plasma proteins, Predicted secreted proteins" "Antioxidant, Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 19.4;BJ: 10.8;PC-3: 15.6;RPTEC TERT1: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042110 Supported "Secreted to blood" 50375000 830000000 "HPA042110: " "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (8.80e-2)" "unprognostic (3.32e-2)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (4.98e-2)" "unprognostic (3.68e-1)" "unprognostic (2.39e-1)" "unprognostic (3.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-2)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.45e-2)" 90.0 9.9 3.7 13.8 5.0 0.8 31.9 1.6 8.3 46.4 24.7 14.7 8.0 10.4 34.4 21.1 52.1 39.5 55.1 61.9 6.4 1.9 40.4 3.9 40.1 6.7 3.4 6.2 36.1 41.0 1.6 4.6 30.4 24.3 40.0 8.1 45.0 13.7 15.5 16.1 19.9 13.7 53.6 5.4 8.4 25.4 25.9 2.1 4.4 68.0 25.2 17.7 61.1 52.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 5.1 0.5 10.8 4.7 0.6 0.4 0.1 0.0 0.0 3.4 2.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.9 0.0 4.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 2.3 15.6 0.0 0.0 0.1 65.8 0.2 0.0 0.0 0.0 0.3 0.0 9.8 0.0 0.0 2.5 0.3 0.4 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.0 1.6 8.3 6.4 1.9 3.4 6.2 24.3 2.1 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023104-45077185 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 66.3;liver: 98.4;thyroid gland: 116.3" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in all" "prostate cancer: 72.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "eosinophil: 36.4" "Lineage enriched" "Detected in many" 13 "granulocytes: 36.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol 430000 Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favourable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 1.4 10.2 3.0 1.5 3.2 1.0 7.1 3.1 3.8 66.3 5.5 6.2 39.2 2.6 2.6 3.2 6.7 3.5 3.9 3.4 3.0 3.0 20.9 98.4 1.6 2.2 4.2 2.3 1.6 7.3 1.2 1.8 0.5 5.0 48.5 3.8 2.3 7.6 46.7 1.4 8.0 8.7 2.0 5.0 2.4 5.6 2.5 3.9 3.1 116.3 3.8 3.5 4.2 4.4 1.6 2.4 36.4 2.7 0.4 1.0 1.3 15.8 13.9 3.5 11.4 3.1 5.4 3.7 4.4 3.0 10.0 8.5 11.5 8.6 2.0 9.9 5.4 23.8 18.2 16.6 8.0 34.3 11.3 15.9 18.2 25.5 2.3 27.5 26.6 6.9 12.6 5.7 9.2 9.3 17.7 5.6 9.4 6.3 16.6 14.9 13.6 14.8 0.0 23.0 7.7 7.3 15.4 25.0 13.1 8.9 14.1 6.7 20.3 11.3 8.3 8.0 7.0 17.8 10.5 1.0 6.9 2.0 12.9 24.4 20.7 5.0 2.7 36.4 0.6 2.5 1.0 1.2 0.6 0.8 2.4 1.6 0.5 0.6 1.4 0.4 2.5 1.3 0.6 1.3 3.0 3.2 3.1 3.8 3.0 3.0 4.2 2.3 5.0 3.9 SPACA5 "dJ54B20.3, LYC5, LYZL5, PNPK6288, SLLP2, UNQ6288" ENSG00000171489 "Sperm acrosome associated 5" Q96QH8 X 48004336-48009729 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 15.1" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;NB-4: 3.9;RPMI-8226: 1.1;T-47d: 1.1;U-266/70: 1.2;U-266/84: 2.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 1.9" "Low lineage specificity" "Detected in single" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" "HPA044747: , HPA047149: " 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.8 0.0 0.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.5 0.4 0.3 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.2 0.0 0.0 15.1 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.9 0.9 0.0 0.4 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.4 0.0 0.7 0.0 1.2 2.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 1.9 0.3 SPACA5B LYZL5B ENSG00000171478 "Sperm acrosome associated 5B" Q96QH8 X 48130657-48132613 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 18.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 19 "T-reg: 1.9" "Lineage enriched" "Detected in single" 19 "T-cells: 1.9" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" "HPA044747: , HPA047149: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 SPAM1 "HYAL5, PH-20, SPAG15" ENSG00000106304 "Sperm adhesion molecule 1" P38567 7 123925237-123971414 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 19.6" "Cell line enhanced" "Detected in some" "BEWO: 1.2;NTERA-2: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA017984 Enhanced "HPA017984: AB_1857413" "unprognostic (2.44e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPAST "ADPSP, FSP2, KIAA1083, SPG4" ENSG00000021574 Spastin Q9UBP0 2 32063547-32157637 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis" "Allosteric enzyme, Developmental protein, Isomerase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017311 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA017311: AB_1857415" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (5.33e-2)" "unprognostic (3.90e-2)" "unprognostic (3.75e-2)" "unprognostic (4.00e-2)" "prognostic unfavourable (1.62e-4)" "unprognostic (3.26e-2)" "unprognostic (2.35e-2)" "unprognostic (7.39e-2)" "unprognostic (5.98e-2)" "unprognostic (3.52e-1)" "prognostic unfavourable (4.15e-4)" "unprognostic (5.71e-2)" "unprognostic (3.04e-1)" "unprognostic (1.53e-2)" "unprognostic (1.13e-1)" 12.7 9.6 18.4 14.8 16.4 13.4 9.8 21.1 21.9 14.7 12.7 15.1 12.5 11.5 12.3 8.7 11.1 10.4 10.2 6.2 20.2 18.5 9.4 14.6 9.7 18.9 20.6 10.0 15.1 10.9 11.8 12.3 11.5 17.5 10.3 12.0 6.8 9.3 13.7 15.4 11.5 17.6 11.6 27.0 15.5 9.7 14.4 14.6 21.5 13.4 6.2 13.8 11.3 10.1 5.0 7.1 9.5 9.0 6.6 7.6 4.3 10.6 7.7 12.6 12.4 8.0 9.4 11.4 5.9 8.7 6.2 5.6 10.4 9.3 18.6 5.5 8.2 7.6 12.4 6.0 7.7 12.5 7.5 20.5 4.2 12.7 7.3 14.2 14.4 5.2 7.9 7.9 7.6 13.7 16.6 6.3 6.8 4.5 22.8 12.0 13.1 4.5 12.1 17.8 12.1 8.4 6.6 18.0 19.3 10.0 8.5 9.8 5.5 9.8 11.8 6.9 10.6 6.1 6.9 9.5 17.7 15.1 7.5 12.3 8.2 3.4 6.3 6.7 3.6 9.0 5.2 5.0 5.8 5.6 7.1 3.9 5.9 6.0 9.5 6.6 6.3 3.2 7.6 4.3 18.4 16.4 21.1 15.8 20.2 18.5 20.6 10.0 17.5 14.6 SPEG "APEG1, BPEG, KIAA1297, MGC12676, SPEGalpha, SPEGbeta" ENSG00000072195 "SPEG complex locus" Q15772 2 219434846-219498287 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 88.7" "Cell line enhanced" "Detected in many" "U-138 MG: 14.7;U-2 OS: 15.0;U-251 MG: 13.7;U-87 MG: 16.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 7.7 7.1 10.1 9.1 7.7 1.2 4.2 10.4 9.8 19.2 45.1 4.1 10.5 5.7 31.6 14.1 13.5 19.0 17.4 17.8 8.7 5.3 2.0 1.4 3.0 1.7 4.0 8.0 7.0 2.9 4.7 10.5 4.8 5.5 16.7 4.5 6.7 7.8 23.0 88.7 2.2 9.2 45.2 9.1 1.9 16.1 3.0 3.9 0.0 2.0 16.8 1.6 22.5 12.6 0.0 0.3 0.0 0.0 0.0 0.5 0.7 4.0 0.3 2.1 3.5 1.1 3.2 1.4 8.7 5.8 5.8 4.4 3.1 1.4 0.0 3.2 6.4 5.1 1.7 2.0 2.3 0.5 1.3 0.4 3.7 0.2 1.5 0.0 0.7 9.3 3.1 5.3 1.3 0.0 3.0 0.0 4.2 1.1 0.1 12.4 4.4 1.6 2.1 4.7 0.7 5.7 0.0 2.3 10.9 0.6 0.0 0.1 0.3 0.1 0.1 14.7 15.0 1.7 13.7 0.5 0.0 0.1 16.6 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.7 10.1 7.7 10.4 9.8 8.7 5.3 4.0 8.0 5.5 3.9 SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 33.7;U-251 MG: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 8.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 5 "olfactory region: 11.7" "HPA022829, HPA028761" Uncertain Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (1.04e-1)" "unprognostic (6.30e-2)" "unprognostic (1.09e-2)" "unprognostic (8.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (9.32e-3)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (8.99e-3)" "unprognostic (2.18e-1)" "prognostic unfavourable (5.14e-6)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-3)" 9.3 2.2 4.7 10.5 3.5 15.0 20.4 0.4 3.2 5.5 5.0 4.0 0.4 1.9 6.3 8.3 13.8 5.3 12.7 10.5 5.3 2.1 4.1 2.4 12.9 10.1 4.4 1.5 5.5 15.1 3.1 2.7 7.4 4.7 4.3 1.1 11.0 11.5 1.7 6.8 8.7 6.3 5.2 4.0 2.7 3.8 3.7 6.3 3.0 9.4 16.2 12.1 5.6 7.0 0.2 8.0 2.4 3.4 0.1 1.4 1.3 9.6 1.0 4.2 0.2 2.1 2.0 4.4 22.3 14.8 18.8 11.4 5.2 1.0 0.4 2.0 16.4 2.0 3.2 28.6 4.6 0.4 1.7 0.1 7.1 33.7 4.7 0.3 0.8 3.8 0.5 29.3 11.6 18.1 4.5 0.0 3.7 12.3 0.9 0.1 0.2 8.1 0.6 1.1 0.7 1.0 0.1 0.5 1.0 2.2 0.2 19.3 0.8 1.3 29.4 29.6 5.7 22.7 37.7 0.4 0.1 0.4 22.5 1.7 4.4 2.4 3.4 0.0 1.4 1.7 0.4 0.0 0.2 0.4 1.0 0.2 0.0 0.3 0.4 0.1 0.3 8.0 0.0 1.3 4.7 3.5 0.4 3.2 5.3 2.1 4.4 1.5 4.7 6.3 SPHK2 ENSG00000063176 "Sphingosine kinase 2" Q9NRA0 19 48619291-48630717 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 33.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065508 Supported Vesicles Vesicles "HPA065508: " "unprognostic (5.33e-2)" "unprognostic (4.11e-2)" "unprognostic (9.61e-2)" "prognostic unfavourable (5.19e-4)" "unprognostic (2.10e-1)" "unprognostic (7.19e-3)" "unprognostic (3.04e-1)" "unprognostic (4.45e-3)" "unprognostic (7.28e-2)" "unprognostic (2.80e-1)" "prognostic favourable (9.30e-4)" "unprognostic (1.25e-1)" "prognostic favourable (2.59e-5)" "unprognostic (1.18e-2)" "unprognostic (9.97e-2)" "unprognostic (4.21e-2)" "unprognostic (7.06e-2)" 9.3 8.9 12.6 9.9 13.0 5.2 5.1 13.6 22.0 7.2 12.9 13.4 4.9 33.2 7.4 4.2 4.9 7.3 7.8 4.7 22.5 14.8 19.3 15.2 6.1 8.7 26.3 14.9 9.1 7.2 15.0 9.5 4.1 22.3 8.7 6.2 7.2 7.5 8.0 6.1 4.3 22.2 4.9 14.1 8.4 11.3 17.2 13.7 4.0 9.1 3.1 5.3 6.2 12.4 10.4 7.4 12.5 9.4 7.2 7.0 4.2 4.0 11.7 4.4 8.0 4.8 2.0 8.3 4.4 3.7 5.2 6.2 20.0 5.4 7.6 3.0 2.8 3.0 4.1 3.6 0.7 8.6 9.6 8.4 5.1 7.0 7.6 5.4 9.3 3.7 1.9 3.6 2.5 2.8 5.5 6.8 2.5 4.2 12.6 33.3 5.8 5.7 11.7 3.5 4.9 2.4 2.7 15.9 12.6 4.2 6.7 4.2 3.6 3.6 4.5 7.4 4.1 5.8 8.8 13.1 15.1 8.4 4.3 6.2 6.7 12.5 8.3 3.6 6.0 9.4 5.9 6.5 4.8 5.8 7.4 10.4 6.6 7.0 3.3 7.2 7.4 6.6 4.6 4.2 12.6 13.0 13.6 22.0 22.5 14.8 26.3 14.9 22.3 13.7 SPPL2A "IMP3, PSL2" ENSG00000138600 "Signal peptide peptidase like 2A" Q8TCT8 15 50702266-50765808 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036062, HPA067304" Enhanced Supported Vesicles Vesicles "HPA036062: AB_10611670, HPA067304: " "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (5.82e-3)" "unprognostic (3.71e-1)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (6.36e-2)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (3.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-2)" "unprognostic (6.96e-2)" "unprognostic (3.66e-1)" 20.5 23.5 6.9 18.0 8.6 15.0 23.3 6.2 8.1 16.4 29.3 10.8 15.3 24.9 14.5 17.9 18.7 13.0 14.9 37.6 7.8 5.3 23.3 44.8 19.2 23.9 8.3 6.1 13.2 32.7 61.0 11.8 32.2 14.4 14.7 26.9 14.9 21.7 15.5 63.1 15.8 39.2 20.5 8.5 21.2 18.3 10.2 7.4 21.6 15.6 17.4 17.7 19.7 13.9 9.8 19.4 24.0 27.3 11.9 15.4 22.4 15.2 26.5 10.3 13.7 40.9 24.4 16.3 24.6 41.3 22.6 32.3 30.7 17.7 9.5 18.4 48.1 23.0 12.4 14.9 25.3 19.4 7.6 18.0 18.2 15.9 33.8 11.1 29.4 21.2 27.5 18.7 30.3 22.2 13.5 37.4 29.8 35.2 5.2 4.3 4.5 6.0 6.5 16.1 20.8 31.1 35.5 8.3 9.4 14.8 28.6 16.6 20.3 22.1 27.0 36.6 14.7 23.4 28.9 15.2 26.0 10.5 16.5 18.8 24.9 21.2 26.9 24.0 15.4 24.6 9.7 9.8 12.6 13.9 19.4 9.3 7.2 11.5 19.4 11.9 27.3 17.1 15.4 22.4 6.9 8.6 6.2 8.1 7.8 5.3 8.3 6.1 14.4 7.4 SPPL2B "IMP4, KIAA1532, PSL1" ENSG00000005206 "Signal peptide peptidase like 2B" Q8TCT7 19 2328615-2354806 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005592, HPA039292" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" "Nucleoplasm, Plasma membrane" Centrosome "CAB005592: AB_325074, HPA039292: " "unprognostic (4.16e-2)" "unprognostic (2.97e-2)" "unprognostic (2.48e-2)" "prognostic favourable (5.00e-5)" "unprognostic (2.34e-1)" "unprognostic (1.54e-3)" "unprognostic (1.74e-1)" "unprognostic (7.93e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "prognostic favourable (1.33e-4)" "unprognostic (3.29e-3)" "prognostic unfavourable (6.45e-4)" "unprognostic (2.26e-2)" "unprognostic (2.45e-1)" "unprognostic (3.02e-1)" "unprognostic (3.40e-2)" 5.4 4.6 5.0 11.7 5.4 11.7 4.0 6.9 6.9 3.4 9.0 7.9 9.6 19.3 4.7 10.0 3.2 5.2 9.8 3.3 5.6 4.2 3.9 3.5 10.3 7.1 4.7 3.4 13.8 6.3 11.0 6.8 7.1 4.7 3.9 6.0 10.5 8.7 7.5 8.7 16.2 5.0 7.0 8.1 13.8 20.1 6.4 9.3 3.0 3.7 5.7 2.3 2.0 14.4 17.4 9.3 7.7 6.2 8.2 5.9 8.3 13.3 5.7 10.2 4.7 4.8 14.7 10.9 3.2 4.0 4.3 9.3 9.5 8.0 10.3 5.1 11.2 1.9 3.7 1.2 9.3 8.3 5.3 20.9 12.5 8.9 9.3 6.9 7.0 4.3 3.8 2.7 5.6 8.5 20.4 2.4 9.2 10.0 11.8 10.7 5.5 16.8 3.0 21.9 4.3 21.0 10.2 9.7 10.9 6.7 8.4 11.1 15.6 12.4 7.3 5.3 18.5 8.5 26.9 9.6 8.3 9.2 10.9 12.7 9.3 7.7 7.0 6.6 7.5 4.8 9.0 6.0 6.5 9.4 14.4 7.8 8.2 3.4 6.2 5.1 17.4 5.9 5.9 SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904371 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "HPA004194: , HPA059958: " "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavourable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" 17.8 15.3 18.9 12.8 23.1 13.9 19.4 21.8 31.4 25.2 20.4 25.6 18.4 14.0 23.1 13.3 39.5 23.3 18.2 13.9 17.4 18.3 18.3 14.9 20.8 21.5 19.2 20.6 25.9 19.6 42.4 14.3 21.9 16.5 16.9 21.7 19.1 19.2 22.7 13.8 48.3 18.5 23.5 17.1 19.0 14.2 34.7 20.8 25.2 24.7 22.2 20.6 19.8 29.3 4.1 6.3 7.3 2.9 2.8 4.4 1.5 12.3 12.3 18.7 11.7 24.8 16.8 13.2 9.5 28.4 20.5 16.5 12.8 12.7 11.4 0.1 16.5 15.2 19.1 20.5 21.3 9.0 11.7 9.8 7.4 9.7 26.2 11.2 12.7 16.8 32.9 17.6 16.5 20.1 10.7 5.7 17.6 10.9 14.9 9.0 12.5 8.8 8.9 15.8 8.1 16.1 35.2 12.8 13.8 18.1 8.4 14.3 25.2 7.8 14.9 9.5 13.0 5.8 7.1 13.4 24.0 11.1 14.2 9.4 15.7 7.3 2.9 2.6 3.2 2.8 4.4 3.2 4.0 4.0 4.9 4.1 3.9 4.3 5.5 2.8 2.4 6.3 3.1 1.5 18.9 23.1 21.8 31.4 17.4 18.3 19.2 20.6 16.5 20.8 SPR SDR38C1 ENSG00000116096 "Sepiapterin reductase" P35270 2 72887360-72892158 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 61.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 9.3;intermediate monocyte: 2.6;myeloid DC: 9.9" "Group enriched" "Detected in many" 13 "dendritic cells: 9.9;monocytes: 9.3" "Low region specificity" "Detected in all" HPA039505 Uncertain Supported Nucleoplasm,Cytosol 52000 "Nucleoplasm, Cytosol" "HPA039505: AB_10795466" "unprognostic (4.09e-1)" "unprognostic (1.22e-1)" "unprognostic (7.72e-3)" "unprognostic (1.97e-1)" "unprognostic (2.46e-2)" "unprognostic (1.06e-2)" "unprognostic (1.36e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-1)" "unprognostic (9.79e-2)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (7.50e-3)" "unprognostic (2.87e-1)" "unprognostic (1.43e-3)" "unprognostic (1.95e-1)" 13.3 22.6 6.3 6.1 8.2 0.0 36.2 2.0 6.4 6.0 17.1 3.1 8.9 11.4 5.7 19.1 13.4 13.2 11.4 16.1 6.4 6.0 20.3 43.5 7.2 5.3 7.9 5.0 8.7 61.7 16.7 5.5 3.9 7.9 17.3 16.2 4.5 20.9 8.8 16.0 3.3 15.1 9.5 4.9 4.7 15.4 4.9 7.2 1.0 31.7 6.2 3.6 9.5 41.4 0.0 9.9 0.7 9.3 0.0 0.4 2.5 13.9 39.2 0.2 6.1 16.1 5.8 9.8 6.6 9.6 4.9 4.6 24.9 14.5 10.2 7.9 7.8 13.2 17.5 10.5 4.1 2.9 13.6 15.3 9.7 25.5 6.0 2.4 4.2 5.2 11.8 5.4 6.1 12.9 15.7 2.0 6.4 29.4 0.9 9.1 3.3 37.5 0.0 25.5 6.0 26.0 21.9 2.4 4.6 12.1 27.3 8.9 12.3 2.9 15.8 5.4 13.2 9.4 11.5 2.2 4.9 0.7 7.7 5.2 9.3 0.0 9.3 0.7 0.4 2.6 0.4 0.0 0.2 0.1 9.9 0.0 0.2 0.4 0.0 0.0 1.0 0.9 0.0 2.5 6.3 8.2 2.0 6.4 6.4 6.0 7.9 5.0 7.9 7.2 SPTLC1 "hLCB1, HSAN1, HSN1, LCB1, SPTI" ENSG00000090054 "Serine palmitoyltransferase long chain base subunit 1" O15269 9 92000087-92115384 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010860, CAB018747, HPA063907" Supported Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB018747: AB_2195864, HPA010860: AB_1080086, HPA063907: " "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.06e-1)" "unprognostic (3.55e-3)" "unprognostic (8.37e-2)" "prognostic favourable (1.36e-6)" "unprognostic (1.13e-1)" "unprognostic (2.41e-2)" "unprognostic (4.28e-1)" "unprognostic (1.49e-1)" 16.4 17.7 13.3 11.4 17.1 9.9 16.8 19.9 17.6 20.3 17.2 20.9 18.1 14.0 17.3 15.1 30.5 19.2 15.5 11.4 13.9 15.3 19.0 13.5 14.8 10.6 18.0 12.2 35.3 15.8 23.6 23.1 28.3 20.5 14.5 18.8 12.0 18.5 13.3 9.4 20.1 17.8 15.1 20.8 10.7 16.0 19.8 14.1 9.7 26.2 16.0 16.5 17.4 20.9 9.3 21.0 21.1 22.1 10.2 15.2 16.0 18.1 16.4 11.4 9.5 27.9 21.7 19.7 19.1 24.4 16.5 17.9 10.3 37.9 10.0 12.2 24.1 47.6 12.3 16.2 19.2 11.5 7.1 9.2 9.3 10.0 21.0 15.2 12.5 19.6 19.6 17.0 18.6 15.0 21.5 12.5 18.7 19.5 9.5 3.8 15.3 12.0 10.6 13.8 7.6 16.4 11.1 9.3 8.6 25.7 19.7 11.6 10.1 9.0 19.0 16.1 12.4 18.5 13.3 9.0 12.3 5.6 19.2 7.5 19.3 14.6 22.1 11.9 11.5 21.6 11.0 8.9 11.6 11.6 21.0 9.3 14.2 10.7 21.1 10.2 19.2 10.8 15.2 16.0 13.3 17.1 19.9 17.6 13.9 15.3 18.0 12.2 20.5 14.1 SPTLC2 "hLCB2a, KIAA0526, LCB2, LCB2A" ENSG00000100596 "Serine palmitoyltransferase long chain base subunit 2" O15270 14 77505997-77616773 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027552 Approved Mitochondria Mitochondria "HPA027552: AB_10601717" "unprognostic (3.16e-1)" "unprognostic (2.82e-2)" "unprognostic (1.24e-1)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" "prognostic unfavourable (3.62e-4)" "unprognostic (1.46e-2)" "unprognostic (3.09e-1)" "unprognostic (4.05e-1)" "unprognostic (1.98e-2)" "unprognostic (2.51e-1)" "prognostic favourable (6.69e-8)" "unprognostic (1.29e-2)" "unprognostic (2.35e-1)" "unprognostic (4.94e-2)" "unprognostic (1.32e-1)" 30.0 12.8 15.4 11.4 27.0 27.3 25.6 6.9 18.5 15.3 17.0 32.4 8.5 13.4 10.2 7.6 22.8 13.7 11.1 7.8 20.8 14.1 17.1 7.2 12.2 17.5 33.1 13.3 10.2 7.6 12.8 9.8 18.8 21.2 8.2 18.8 6.0 16.6 9.6 5.5 11.3 15.8 11.0 47.6 23.5 18.8 4.7 34.9 10.0 10.3 8.8 12.0 13.2 17.1 4.8 18.2 15.1 18.2 10.0 4.2 6.9 11.9 7.9 6.1 6.6 6.3 7.9 10.3 17.8 13.2 12.3 12.9 10.0 26.7 12.0 4.5 18.1 14.8 16.1 10.0 18.7 5.2 4.7 33.9 6.1 5.9 5.3 3.4 11.3 5.1 4.9 8.0 8.9 17.3 6.6 5.8 7.0 10.3 9.0 11.7 3.9 7.1 9.7 6.2 4.1 14.2 26.9 5.9 7.4 6.4 21.5 6.7 26.4 6.3 10.8 11.3 8.1 4.1 4.1 3.3 5.4 8.1 7.5 12.2 6.4 8.8 18.2 15.1 3.8 13.8 3.5 4.1 3.2 4.2 18.2 4.8 2.2 3.6 11.2 10.0 16.7 6.5 3.3 6.9 15.4 27.0 6.9 18.5 20.8 14.1 33.1 13.3 21.2 34.9 SPTLC3 "C20orf38, FLJ11112, hLCB2b, LCB2B, SPTLC2L" ENSG00000172296 "Serine palmitoyltransferase long chain base subunit 3" Q9NUV7 20 13008979-13169103 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "placenta: 154.0" "Cell line enhanced" "Detected in many" "Karpas-707: 16.0;RPTEC TERT1: 21.4;U-2197: 14.9;U-87 MG: 28.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "pons and medulla: 10.5" "Group enriched" "Detected in some" 5 "MAIT T-cell: 3.0;NK-cell: 4.1" "Group enriched" "Detected in many" 13 "NK-cells: 4.1;T-cells: 3.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA044247, HPA048079" Enhanced Approved Microtubules Microtubules "HPA044247: , HPA048079: " "unprognostic (6.81e-2)" "unprognostic (7.76e-2)" "unprognostic (4.46e-2)" "unprognostic (1.25e-3)" "unprognostic (5.43e-2)" "unprognostic (2.12e-1)" "unprognostic (5.70e-2)" "unprognostic (7.99e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "prognostic unfavourable (6.02e-4)" "unprognostic (5.08e-2)" "prognostic favourable (4.51e-7)" "unprognostic (2.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.18e-1)" 3.2 4.5 1.3 1.6 2.2 0.0 4.3 1.7 1.7 4.3 5.0 2.2 4.4 8.3 4.8 9.6 5.6 3.4 5.8 4.8 2.0 1.5 15.6 11.9 5.7 0.7 2.5 2.2 4.3 3.8 10.2 4.2 154.0 10.5 4.5 3.8 3.8 7.8 5.8 1.0 25.1 9.0 3.0 6.9 1.9 2.2 4.2 1.4 5.7 24.3 3.6 1.9 4.8 6.0 0.0 0.2 0.1 0.0 4.1 3.0 0.2 0.6 1.1 0.8 0.0 7.0 10.1 5.4 0.0 1.5 1.0 4.1 8.7 4.4 0.0 0.5 0.2 12.0 0.0 3.3 1.4 0.0 0.0 0.0 2.8 12.3 0.6 0.0 0.1 5.7 10.4 4.0 1.3 0.6 0.0 16.0 11.3 0.2 0.0 0.0 0.0 1.4 1.1 2.0 7.0 21.4 8.6 0.0 0.1 0.1 1.1 0.0 8.9 0.2 1.5 4.5 1.5 14.9 1.0 0.1 0.0 0.0 28.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 3.0 0.0 0.4 0.1 0.0 0.0 0.7 0.1 0.1 4.1 0.0 0.2 0.0 0.2 1.3 2.2 1.7 1.7 2.0 1.5 2.5 2.2 10.5 1.4 SQLE ENSG00000104549 "Squalene epoxidase" Q14534 8 124998497-125022283 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018038, HPA020762" Enhanced Uncertain Vesicles,Cytosol "Vesicles, Cytosol" "HPA018038: , HPA020762: " "unprognostic (1.37e-2)" "unprognostic (6.26e-3)" "unprognostic (5.12e-2)" "unprognostic (9.51e-3)" "unprognostic (4.63e-1)" "prognostic unfavourable (7.42e-4)" "unprognostic (4.76e-3)" "prognostic unfavourable (4.67e-4)" "unprognostic (3.45e-2)" "unprognostic (7.21e-2)" "prognostic unfavourable (2.73e-4)" "unprognostic (7.51e-2)" "prognostic unfavourable (5.70e-4)" "unprognostic (9.71e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-3)" "unprognostic (7.74e-3)" 4.6 15.7 11.1 9.9 13.9 10.4 12.1 8.9 19.9 15.1 11.5 28.8 4.4 15.8 8.9 5.1 40.3 10.0 6.3 4.2 15.4 14.5 7.8 38.1 16.0 8.6 10.8 9.7 17.5 6.3 16.5 9.5 24.7 28.5 13.8 10.1 9.3 10.4 4.7 1.3 23.8 8.7 6.6 36.0 5.6 11.5 29.3 18.7 9.8 5.7 24.2 15.0 5.3 21.6 15.1 12.4 1.2 9.7 9.5 9.0 6.1 25.5 9.9 59.4 17.0 18.5 31.4 6.0 6.7 20.7 9.2 16.9 13.4 37.3 17.6 9.7 8.3 19.5 24.7 37.2 10.7 14.5 52.3 50.2 6.7 34.2 27.2 5.9 14.8 21.4 39.8 27.4 22.6 10.0 28.6 34.3 7.4 42.1 20.3 7.4 24.6 6.8 8.9 10.9 23.9 64.7 29.4 18.6 9.4 13.8 44.4 13.8 11.8 15.4 9.8 3.8 13.4 4.5 6.0 6.2 12.6 24.1 6.4 17.9 6.5 1.2 5.1 0.5 9.0 8.5 4.4 13.6 5.4 8.3 12.4 15.1 7.5 7.8 0.1 9.5 9.7 8.8 5.6 6.1 11.1 13.9 8.9 16.4 15.4 14.5 10.8 9.7 28.5 18.7 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 35.5;HBEC3-KT: 33.0;PC-3: 32.1;RT4: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 5.3;non-classical monocyte: 4.4" "Group enriched" "Detected in many" 6 "dendritic cells: 3.0;monocytes: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Plasma membrane,Cell Junctions,Cytosol" 20000000 "Plasma membrane, Cell Junctions" Cytosol "CAB004023: AB_2106059, HPA030875: " "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavourable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavourable (1.63e-4)" "prognostic unfavourable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favourable (5.22e-5)" 6.9 17.5 12.8 11.1 12.0 5.4 9.9 6.4 16.0 16.0 16.4 3.5 15.1 29.5 20.3 9.7 16.2 14.2 42.1 5.8 11.3 6.6 13.4 2.9 10.4 7.0 3.3 9.9 15.8 19.1 6.6 11.3 6.3 5.1 19.9 13.1 13.1 7.5 22.5 3.4 7.7 28.1 27.2 3.6 12.2 29.8 27.3 4.8 4.0 6.6 10.5 10.4 26.4 20.0 0.3 3.0 0.1 5.3 0.6 0.1 1.6 7.6 35.5 8.1 7.3 3.1 4.9 17.0 7.1 6.1 8.6 5.5 13.3 6.9 0.2 4.4 12.8 14.0 4.9 33.0 3.4 0.0 4.4 1.9 1.2 20.7 7.4 0.1 3.0 5.3 11.2 5.6 7.5 7.8 0.2 0.0 1.4 5.2 1.8 0.2 3.8 32.1 8.3 2.1 0.2 3.6 34.0 7.6 27.5 8.0 11.3 8.8 10.1 2.8 11.5 10.4 7.0 3.8 6.3 0.1 0.2 0.1 7.3 0.0 7.7 0.0 2.6 0.0 0.0 5.3 0.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.1 0.6 4.4 3.0 0.1 1.6 12.8 12.0 6.4 16.0 11.3 6.6 3.3 9.9 5.1 4.8 SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633343-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved "HPA051402: " "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavourable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" 2.4 3.3 7.7 2.9 8.2 3.2 14.8 9.2 11.8 5.6 5.2 5.3 0.7 5.7 3.1 4.6 24.2 2.9 4.0 1.9 9.3 7.5 6.4 42.4 3.0 3.5 6.2 5.5 4.1 4.3 3.0 1.9 2.1 13.4 2.6 3.6 2.4 5.0 2.1 2.2 17.5 10.4 2.6 3.1 2.9 3.9 2.7 2.9 3.3 2.4 15.3 12.1 2.6 10.1 1.9 3.7 7.0 3.3 1.3 1.3 1.3 5.5 5.5 7.3 6.2 7.0 6.9 3.4 5.4 4.1 5.3 3.3 5.5 4.9 6.7 8.9 7.8 9.0 5.9 3.6 5.7 4.1 2.5 2.1 13.7 3.3 3.2 3.0 1.8 5.0 10.2 3.8 3.0 2.6 3.6 6.2 6.8 6.5 1.4 3.4 4.6 4.4 4.6 5.6 2.0 7.1 5.2 13.8 6.3 16.4 7.3 5.0 3.0 0.8 5.4 8.1 4.0 13.1 6.7 3.3 4.4 2.4 6.7 3.5 7.4 7.0 3.3 1.4 1.0 2.4 0.7 1.7 1.0 1.3 3.7 1.9 0.9 1.0 2.0 1.3 2.6 1.8 1.1 1.3 7.7 8.2 9.2 11.8 9.3 7.5 6.2 5.5 13.4 2.9 SRD5A3 "FLJ13352, SRD5A2L, SRD5A2L1" ENSG00000128039 "Steroid 5 alpha-reductase 3" Q9H8P0 4 55346109-55373096 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Cataract, Congenital disorder of glycosylation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027006 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA027006: AB_1857469" "unprognostic (1.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-2)" "prognostic favourable (9.39e-4)" "unprognostic (1.50e-2)" "unprognostic (4.81e-2)" "prognostic unfavourable (1.80e-6)" "unprognostic (9.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.81e-2)" "unprognostic (3.29e-3)" "unprognostic (1.18e-1)" "prognostic unfavourable (4.85e-10)" "unprognostic (4.16e-2)" "unprognostic (1.42e-1)" "unprognostic (1.43e-2)" "unprognostic (9.52e-2)" 13.8 12.2 11.5 5.9 13.4 6.6 17.8 7.3 18.3 22.9 11.3 20.3 3.5 6.9 13.8 9.6 24.4 5.9 22.6 10.5 13.2 10.7 12.3 15.0 12.4 10.1 15.5 12.0 3.5 26.8 14.0 7.0 8.8 13.6 8.9 10.9 6.8 16.3 6.6 5.8 15.6 8.3 6.2 22.1 6.9 13.8 4.0 15.3 10.0 7.6 9.9 12.1 12.1 12.1 5.9 28.4 10.3 25.2 3.6 9.2 10.3 4.9 3.3 6.0 5.7 20.0 12.8 3.0 5.4 6.3 2.3 3.7 3.3 10.4 11.8 6.1 8.5 3.9 4.2 5.0 2.8 3.4 7.5 6.4 3.7 8.8 5.3 11.9 3.6 11.7 9.3 3.9 3.6 9.2 10.9 26.5 12.9 6.5 17.4 5.2 7.5 4.4 5.6 1.8 6.6 7.6 5.4 9.2 5.1 5.8 43.6 3.9 5.3 10.5 4.5 14.6 2.6 1.0 4.1 14.1 7.7 4.3 18.5 16.4 14.2 10.3 16.5 4.9 7.9 25.1 9.2 5.9 6.0 7.4 14.1 5.2 5.3 7.1 0.8 3.6 25.2 28.4 5.8 10.3 11.5 13.4 7.3 18.3 13.2 10.7 15.5 12.0 13.6 15.3 SRM "SPS1, SRML1" ENSG00000116649 "Spermidine synthase" P19623 1 11054584-11060024 "Enzymes, Predicted intracellular proteins" "Polyamine biosynthesis, Spermidine biosynthesis" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 107.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015746 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA015746: AB_1857472" "unprognostic (4.97e-2)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (2.52e-2)" "unprognostic (1.75e-1)" "unprognostic (1.97e-1)" "prognostic unfavourable (2.25e-5)" "unprognostic (2.11e-2)" "unprognostic (2.44e-1)" "unprognostic (3.58e-2)" "unprognostic (3.01e-1)" "unprognostic (3.45e-1)" "prognostic unfavourable (3.80e-8)" "unprognostic (1.74e-2)" "unprognostic (8.98e-3)" "unprognostic (1.36e-1)" "unprognostic (2.98e-2)" 26.7 17.7 20.3 29.0 35.4 15.2 16.9 10.2 30.8 14.3 13.3 14.0 11.5 10.8 18.8 9.8 17.7 15.8 14.2 24.9 19.6 16.9 13.9 45.3 14.0 31.0 15.3 15.0 22.8 107.4 8.0 14.5 14.8 15.6 13.1 11.7 15.0 36.0 17.6 43.6 18.2 9.8 22.9 11.7 21.1 14.5 14.4 14.1 17.9 11.9 21.2 20.8 20.2 19.8 10.7 10.2 0.3 6.0 5.0 10.3 2.0 24.9 36.3 12.1 40.4 24.1 26.1 19.0 38.8 19.9 55.5 29.8 44.7 15.1 48.2 22.9 33.6 19.6 38.6 31.2 18.4 23.7 58.3 30.4 40.2 50.4 35.5 50.9 27.9 26.2 22.6 53.7 47.1 23.4 49.4 40.9 26.9 54.7 43.4 44.5 26.3 70.4 32.7 12.5 78.7 19.7 9.9 23.3 22.3 20.0 43.3 30.3 15.1 25.9 19.4 36.2 28.5 62.7 43.5 33.0 33.2 72.2 25.2 68.5 41.7 0.0 5.4 0.3 7.0 6.0 10.3 10.7 7.1 9.1 6.4 9.3 8.4 9.7 0.2 5.0 3.1 10.2 7.5 2.0 20.3 35.4 10.2 30.8 19.6 16.9 15.3 15.0 15.6 14.1 SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63540810-63547504 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 10.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.7;HaCaT: 2.6;MCF7: 4.9;RT4: 10.1;T-47d: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "naive B-cell: 1.1" "Lineage enriched" "Detected in single" 8 "B-cells: 1.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: AB_10609403, CAB044669: AB_10608235, HPA073987: " "unprognostic (2.26e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.62e-1)" "unprognostic (5.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.73e-3)" "unprognostic (2.58e-3)" "unprognostic (4.75e-2)" "unprognostic (4.97e-2)" "unprognostic (2.54e-3)" 0.3 0.0 0.3 0.5 0.3 0.0 1.1 1.1 0.3 0.3 1.8 0.3 0.3 0.4 0.3 10.2 0.4 0.0 0.3 0.3 0.3 0.0 0.9 0.3 0.3 0.3 0.3 0.3 0.3 2.7 0.0 0.3 0.3 0.3 2.2 0.0 0.3 2.5 0.3 0.3 1.7 0.8 0.3 0.3 2.5 4.2 0.9 0.3 0.3 0.3 0.3 0.8 1.5 0.3 1.1 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 5.7 0.2 2.3 0.0 2.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.2 0.0 0.8 0.0 0.2 0.0 0.0 10.1 0.8 1.0 0.3 2.1 0.4 2.6 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 1.1 0.3 0.3 0.0 0.3 0.3 0.3 0.3 SRPK1 SFRSK1 ENSG00000096063 "SRSF protein kinase 1" Q96SB4 6 35832966-35921342 "Enzymes, Predicted intracellular proteins" "Chromosome partition, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016431, HPA056486" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA016431: AB_1857478, HPA056486: AB_2683148" "unprognostic (4.65e-3)" "unprognostic (6.82e-3)" "unprognostic (2.54e-3)" "unprognostic (1.01e-3)" "unprognostic (7.74e-2)" "unprognostic (3.31e-2)" "prognostic unfavourable (7.90e-6)" "unprognostic (1.23e-2)" "unprognostic (2.54e-3)" "unprognostic (2.36e-2)" "prognostic unfavourable (6.53e-5)" "unprognostic (7.28e-2)" "unprognostic (2.21e-3)" "unprognostic (9.24e-2)" "unprognostic (4.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.55e-3)" 13.5 7.1 8.1 15.4 11.7 32.1 11.7 22.5 17.8 12.8 23.8 7.8 10.8 20.3 15.2 7.9 24.9 8.9 10.8 8.7 8.9 7.8 17.8 18.9 14.9 14.6 8.0 8.3 9.5 26.0 11.7 17.7 27.9 9.6 10.5 28.7 12.4 17.6 9.4 19.9 26.2 25.7 11.3 7.9 19.0 13.9 32.7 7.6 21.0 8.5 17.0 19.8 15.2 15.7 4.3 2.8 24.6 3.4 5.0 6.7 2.9 29.3 11.1 16.4 24.5 9.2 12.0 20.8 18.0 17.4 16.9 18.0 31.3 9.9 39.2 15.3 11.1 15.1 32.0 21.5 30.3 26.7 23.1 20.6 13.1 27.1 8.2 30.4 10.1 7.7 11.7 19.4 25.4 21.1 43.6 16.6 14.1 10.4 31.3 23.7 13.4 12.2 22.1 19.7 24.2 16.9 49.3 35.1 12.9 18.5 17.6 12.5 9.9 20.3 15.2 15.9 12.4 10.7 22.6 9.8 21.6 36.8 6.3 35.4 14.1 24.5 2.1 13.7 4.3 2.5 6.1 4.3 5.7 5.7 2.8 3.3 4.8 5.2 24.6 5.0 3.4 1.6 6.7 2.9 8.1 11.7 22.5 17.8 8.9 7.8 8.0 8.3 9.6 7.6 SRPK2 SFRSK2 ENSG00000135250 "SRSF protein kinase 2" P78362 7 105110704-105399308 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 69.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 58.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015522, HPA020876" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA015522: AB_1857479, HPA020876: AB_1857480" "unprognostic (9.75e-2)" "unprognostic (1.68e-2)" "unprognostic (1.12e-1)" "unprognostic (4.64e-2)" "unprognostic (3.54e-1)" "unprognostic (1.30e-1)" "unprognostic (5.14e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.19e-1)" "unprognostic (2.31e-1)" "unprognostic (5.38e-2)" "unprognostic (7.95e-2)" "unprognostic (4.72e-2)" "unprognostic (2.87e-2)" "unprognostic (3.44e-1)" 9.9 12.1 24.8 10.1 27.6 7.1 13.3 28.4 47.1 12.7 9.4 21.0 7.8 8.2 13.2 11.9 11.9 10.9 11.6 10.4 26.4 28.6 10.3 10.1 9.2 11.5 27.2 30.2 13.0 10.5 11.9 15.3 12.0 27.3 14.0 10.9 7.9 10.1 11.1 7.9 16.9 8.2 13.3 23.1 12.0 11.3 69.3 32.3 22.1 11.3 4.7 14.0 13.6 9.7 12.2 7.3 58.2 8.1 10.0 11.9 6.0 13.1 8.7 13.9 27.6 14.9 16.9 7.8 12.8 15.1 12.9 15.1 6.8 11.2 8.3 16.4 16.6 7.9 14.1 13.6 16.5 14.4 12.5 11.8 8.2 5.9 17.3 11.2 17.7 11.7 25.3 10.9 20.6 22.1 11.6 34.2 14.2 24.8 41.5 8.5 11.5 9.6 13.5 15.4 18.2 18.6 20.4 20.5 14.2 14.6 22.0 13.5 8.2 7.8 14.5 23.8 17.4 22.6 12.0 37.6 37.0 20.5 9.3 11.6 17.7 11.2 8.1 26.0 11.9 5.5 7.1 12.2 9.0 8.9 7.3 11.6 8.5 9.7 58.2 10.0 6.2 6.4 10.1 6.0 24.8 27.6 28.4 38.7 26.4 28.6 27.2 30.2 27.3 32.3 SRR "ILV1, ISO1" ENSG00000167720 "Serine racemase" Q9GZT4 17 2303383-2325260 "Enzymes, Predicted intracellular proteins" "Allosteric enzyme, Isomerase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007529, CAB015343" Approved Approved Vesicles Vesicles "CAB015343: AB_2195009, HPA007529: " "unprognostic (2.96e-1)" "unprognostic (7.86e-2)" "unprognostic (6.01e-2)" "prognostic favourable (6.20e-5)" "unprognostic (3.05e-1)" "unprognostic (1.57e-2)" "unprognostic (4.32e-2)" "unprognostic (9.97e-2)" "unprognostic (9.09e-2)" "unprognostic (4.85e-2)" "prognostic favourable (8.16e-4)" "unprognostic (5.17e-2)" "prognostic favourable (2.45e-6)" "unprognostic (6.14e-2)" "unprognostic (1.99e-1)" "unprognostic (1.89e-1)" "unprognostic (5.84e-2)" 11.6 12.6 17.1 7.7 14.7 13.9 16.7 12.2 24.9 8.4 10.4 13.9 11.4 7.9 10.9 11.3 12.9 10.0 9.6 12.6 15.2 13.0 10.3 9.0 10.9 7.0 12.6 15.6 9.8 14.8 11.0 9.7 6.5 12.4 9.6 8.8 10.6 11.9 9.3 16.9 13.4 7.5 15.0 13.2 7.3 9.2 13.8 9.0 13.4 13.8 6.1 6.0 12.1 7.3 9.7 15.5 5.2 12.6 13.9 13.5 8.7 7.2 13.2 24.0 8.9 13.1 13.8 11.7 15.4 9.6 10.2 10.6 12.2 9.2 13.6 2.0 15.9 15.3 6.6 5.6 13.0 15.8 12.9 7.0 9.8 4.6 13.2 2.0 3.9 11.7 5.8 22.8 11.0 14.9 7.2 10.1 22.7 4.3 13.9 2.7 5.0 10.0 23.1 27.2 6.3 11.8 3.3 4.7 12.1 13.4 1.6 7.0 10.5 4.9 11.7 11.0 7.8 12.4 9.1 8.9 12.0 2.5 19.6 6.6 14.9 2.4 8.2 5.2 9.5 8.7 9.9 9.7 12.3 10.1 15.5 8.9 10.4 13.5 1.0 13.9 12.6 10.4 8.9 8.7 17.1 14.7 12.2 24.9 15.2 13.0 12.6 15.6 12.4 9.0 SSH1 KIAA1298 ENSG00000084112 "Slingshot protein phosphatase 1" Q8WYL5 12 108778192-108857590 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019845 Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA019845: AB_1857497" "unprognostic (1.18e-3)" "unprognostic (3.00e-1)" "unprognostic (2.49e-1)" "unprognostic (2.70e-2)" "unprognostic (9.40e-2)" "unprognostic (7.45e-2)" "prognostic unfavourable (5.80e-5)" "unprognostic (3.28e-2)" "unprognostic (3.69e-2)" "unprognostic (1.72e-3)" "unprognostic (7.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.71e-2)" "unprognostic (1.41e-1)" "unprognostic (8.66e-2)" "unprognostic (9.55e-2)" "unprognostic (6.22e-2)" 7.3 7.8 8.5 7.4 8.1 10.6 9.3 20.3 8.8 7.4 8.5 6.8 13.1 4.4 9.8 7.9 7.6 8.2 8.3 10.1 8.0 6.9 5.8 7.4 10.1 8.7 7.7 5.2 7.9 8.0 9.7 6.8 7.8 8.4 6.5 6.5 15.0 5.9 8.0 21.4 7.1 6.5 10.4 8.1 8.6 7.1 5.2 6.6 2.0 7.0 7.9 6.6 10.0 13.3 1.8 2.0 5.7 4.0 2.1 2.9 1.2 5.1 6.8 4.5 3.5 8.5 7.2 4.0 6.6 14.1 6.0 5.4 3.4 2.5 2.4 4.7 15.5 5.1 2.7 11.1 4.9 4.9 2.6 5.7 3.1 2.1 4.5 2.9 15.1 9.9 3.8 5.5 12.2 5.5 1.3 2.0 15.8 2.9 3.3 4.2 3.1 5.4 2.4 5.3 3.2 2.4 9.2 3.3 4.5 5.8 1.5 12.7 2.1 2.6 4.3 10.9 4.6 6.5 3.7 3.9 3.5 3.0 5.7 2.4 34.2 4.2 2.4 4.8 2.9 4.0 2.7 1.6 1.5 2.5 1.6 1.8 1.4 1.6 5.7 2.1 3.2 2.0 1.7 1.2 8.5 8.1 20.3 8.8 8.0 6.9 7.7 5.2 8.4 6.6 SSH2 KIAA1725 ENSG00000141298 "Slingshot protein phosphatase 2" Q76I76 17 29625938-29930276 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 37.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017189, HPA057099" Uncertain "CAB017189: , HPA057099: " "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (3.00e-3)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-3)" "unprognostic (7.52e-2)" "unprognostic (1.48e-2)" "unprognostic (8.28e-2)" "unprognostic (7.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" 12.3 7.7 15.8 19.0 16.0 43.1 7.9 23.9 18.0 6.8 10.6 17.5 8.8 7.4 6.1 8.5 9.4 6.5 7.9 12.0 12.9 8.4 10.8 9.8 15.1 20.9 13.6 12.4 3.7 11.8 6.4 6.5 8.8 10.6 5.1 10.0 7.9 8.6 11.6 59.6 10.5 14.5 6.9 12.6 21.3 10.3 26.1 15.2 22.7 10.7 9.5 19.9 7.8 6.5 7.9 4.0 37.8 4.5 1.4 5.9 1.8 11.9 9.7 6.2 5.3 17.3 11.9 3.6 5.9 6.8 9.8 10.4 5.2 4.5 9.9 9.5 7.0 13.9 7.6 8.6 11.4 3.5 13.6 6.9 9.9 7.7 8.2 7.3 14.9 13.9 5.8 10.4 6.9 22.4 4.9 7.8 6.9 3.3 34.5 7.5 4.6 5.0 16.6 15.8 17.4 17.0 9.4 10.5 11.7 8.6 9.6 17.2 6.4 7.7 12.3 6.7 13.7 11.7 7.1 11.8 7.8 24.8 7.9 5.8 6.1 11.0 3.8 37.8 3.5 4.5 2.9 7.5 4.4 3.5 4.0 7.9 4.1 3.0 9.6 1.4 3.8 2.6 5.9 1.8 15.8 16.0 23.9 18.0 12.9 8.4 13.6 12.4 10.6 15.2 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303448-67312607 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 23.6;RT4: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 10.8;eosinophil: 10.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavourable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 8.6 5.5 5.6 6.8 9.7 8.1 13.5 17.8 9.4 14.6 15.9 15.4 19.5 12.4 10.1 10.6 27.0 15.2 20.5 7.7 6.0 6.1 10.3 7.5 9.0 3.5 13.6 5.4 17.1 12.0 11.3 7.4 20.0 8.5 19.8 9.2 11.9 19.1 30.5 5.2 18.2 13.6 13.1 9.3 6.9 13.9 4.2 9.7 0.8 12.8 14.0 13.2 33.3 18.6 0.3 1.6 10.8 2.3 1.5 2.2 1.0 6.1 6.7 0.1 0.2 4.7 4.9 7.3 4.0 5.4 2.1 2.0 7.2 16.3 0.3 12.5 3.7 23.6 2.2 17.0 1.1 1.3 2.5 1.5 10.8 2.9 3.3 0.3 6.0 4.3 15.8 3.1 3.2 2.4 0.0 0.6 2.5 20.8 0.2 3.0 1.5 5.4 7.6 0.2 1.1 6.9 35.7 1.4 2.2 9.4 14.0 4.4 19.6 5.2 3.8 1.7 3.7 4.7 1.1 0.6 0.3 0.2 4.8 2.7 1.6 10.8 1.4 10.5 2.2 2.3 1.7 0.3 2.1 1.8 1.6 0.2 0.8 0.9 4.5 1.5 1.1 1.1 1.8 1.0 5.6 9.7 17.8 9.4 6.0 6.1 13.6 5.4 8.5 9.7 SSU72 HSPC182 ENSG00000160075 "SSU72 homolog, RNA polymerase II CTD phosphatase" Q9NP77 1 1541673-1574869 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069290, HPA070604" Supported Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA069290: , HPA070604: " "unprognostic (3.33e-2)" "unprognostic (2.79e-2)" "unprognostic (6.37e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "unprognostic (9.84e-2)" "unprognostic (2.40e-3)" "unprognostic (2.43e-2)" "unprognostic (3.23e-1)" "unprognostic (3.23e-1)" "unprognostic (6.75e-2)" "unprognostic (1.36e-1)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "unprognostic (8.51e-2)" "unprognostic (3.77e-1)" "unprognostic (1.06e-1)" 44.1 32.5 48.0 33.6 51.5 29.3 73.9 42.3 51.5 37.2 40.1 25.4 39.3 41.3 32.6 51.8 45.7 46.2 35.3 44.4 40.7 42.5 38.0 50.9 37.5 49.0 39.4 39.0 38.0 61.8 33.9 39.9 35.8 36.9 33.9 35.9 34.1 54.2 35.8 107.1 36.9 40.8 35.4 35.0 41.7 38.5 28.0 28.4 37.0 50.9 45.3 36.3 30.8 42.2 35.5 30.1 62.0 28.8 20.7 46.5 28.1 40.6 26.0 18.8 29.0 32.5 31.3 19.3 35.3 27.6 30.9 32.2 24.4 47.2 41.4 19.4 27.8 31.8 30.3 29.1 30.2 34.4 35.9 25.9 22.9 38.6 36.7 32.8 22.7 27.9 24.6 33.1 31.6 28.9 44.8 32.0 24.4 36.2 37.5 52.7 32.9 39.6 29.9 30.4 57.8 33.8 12.5 34.8 23.9 23.9 61.5 104.3 32.0 28.6 21.9 29.8 18.9 33.5 30.3 39.1 46.9 51.6 31.2 52.3 14.4 37.1 28.3 53.6 25.9 28.8 31.9 35.5 34.4 30.7 30.1 33.1 42.2 34.1 62.0 20.7 25.4 19.0 46.5 28.1 48.0 51.5 42.3 51.5 40.7 42.5 39.4 39.0 36.9 28.4 ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "Suppression of tumorigenicity 14" Q9Y5Y6 11 130159562-130210376 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 94.1" "Cell line enhanced" "Detected in some" "CACO-2: 35.7;CAPAN-2: 72.1;HaCaT: 50.5;RPMI-8226: 47.3;SK-BR-3: 33.4;T-47d: 50.5;U-698: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 18.2" "Lineage enriched" "Detected in many" 5 "dendritic cells: 18.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047014 Approved Nucleoplasm,Vesicles 220000 "Nucleoplasm, Vesicles" "HPA047014: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favourable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" 10.1 1.8 0.7 21.9 1.8 0.5 5.5 0.8 1.4 8.9 48.6 0.5 23.8 33.8 2.8 16.9 38.9 9.7 32.4 1.1 0.5 0.5 30.5 3.2 9.5 7.5 1.8 0.6 3.6 34.3 8.4 9.5 12.7 1.5 12.1 15.4 0.7 25.1 15.8 0.7 17.8 94.1 1.2 1.8 4.0 16.7 2.1 1.5 5.2 24.0 20.1 28.4 8.3 14.9 3.8 18.2 2.3 2.7 0.0 0.1 0.8 26.2 0.0 0.0 0.1 0.0 0.0 14.3 0.0 0.0 0.0 0.0 35.7 72.1 26.0 2.7 0.0 50.5 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 20.3 0.0 0.1 0.2 0.1 0.0 0.0 47.3 4.7 21.5 2.9 0.0 0.2 33.4 0.0 50.5 5.1 0.0 0.0 0.4 0.1 0.1 0.0 0.0 34.4 0.0 8.0 0.0 0.0 2.7 2.3 0.0 1.5 0.1 3.8 0.0 0.0 4.5 2.3 0.0 0.0 0.3 0.0 0.2 18.2 0.0 0.8 0.7 1.8 0.8 1.4 0.5 0.5 1.8 0.6 1.5 1.5 ST3GAL1 "SIAT4A, SIATFL, ST3GalA.1, ST3O" ENSG00000008513 "ST3 beta-galactoside alpha-2,3-sialyltransferase 1" Q11201 8 133454848-133571940 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "PC-3: 47.8;RT4: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040466 Approved "Intracellular and membrane" 290000 "HPA040466: AB_10805712" "unprognostic (1.36e-2)" "unprognostic (1.11e-2)" "unprognostic (6.66e-2)" "unprognostic (1.83e-3)" "unprognostic (5.53e-3)" "unprognostic (4.43e-2)" "unprognostic (4.79e-2)" "unprognostic (2.66e-1)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (3.55e-3)" "unprognostic (1.10e-1)" "unprognostic (1.83e-3)" "unprognostic (1.67e-2)" "unprognostic (3.29e-2)" "unprognostic (8.64e-3)" "unprognostic (2.95e-2)" 14.4 14.4 5.1 11.8 3.6 10.2 7.8 3.7 6.5 9.8 5.4 4.1 18.1 1.8 8.5 11.8 9.0 9.0 17.0 35.4 4.2 3.4 23.1 44.5 11.9 12.4 4.7 2.5 10.3 8.2 4.4 7.6 49.8 6.4 7.1 2.9 11.2 18.2 15.1 20.9 4.0 6.5 12.3 3.9 17.3 9.4 5.0 1.4 6.3 40.2 7.9 16.8 14.0 14.3 22.7 7.0 21.3 9.8 21.9 19.9 9.5 4.7 2.5 1.0 2.9 10.3 5.4 5.3 5.4 13.1 2.1 1.6 4.4 5.3 1.1 3.7 10.0 1.4 3.4 4.0 1.9 13.3 0.6 9.9 7.6 8.8 7.9 2.0 7.9 6.3 2.0 7.6 4.2 9.2 0.1 15.4 1.5 5.0 2.8 2.7 0.7 47.8 3.3 1.3 8.1 0.9 36.8 0.2 0.8 2.4 8.2 2.5 1.5 2.7 8.9 6.5 10.3 5.6 2.3 19.0 13.6 1.2 14.8 6.9 6.6 20.5 4.7 21.3 14.4 4.5 13.3 12.8 14.6 16.4 2.9 22.7 19.9 18.5 8.6 21.9 9.8 7.0 8.9 9.5 5.1 3.6 3.7 6.5 4.2 3.4 4.7 2.5 6.4 1.4 ST3GAL2 "SIAT4B, ST3GalA.2, ST3GALII" ENSG00000157350 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" Q16842 16 70375978-70439237 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017270 Approved Approved Vesicles "Intracellular and membrane" Vesicles "HPA017270: AB_1857523" "unprognostic (2.76e-2)" "unprognostic (6.33e-2)" "unprognostic (3.41e-1)" "unprognostic (1.35e-1)" "unprognostic (4.99e-1)" "unprognostic (1.01e-1)" "prognostic unfavourable (2.79e-4)" "unprognostic (1.14e-2)" "unprognostic (2.21e-1)" "unprognostic (1.91e-2)" "prognostic favourable (2.33e-4)" "unprognostic (9.54e-2)" "prognostic unfavourable (3.34e-6)" "unprognostic (7.42e-2)" "unprognostic (8.83e-3)" "unprognostic (4.64e-2)" "unprognostic (5.20e-2)" 12.6 9.1 9.3 17.2 11.9 14.3 8.9 24.1 10.6 11.3 8.8 5.1 9.3 9.2 13.9 5.6 5.8 9.0 6.8 9.2 10.4 6.0 8.8 12.9 9.3 14.9 5.1 4.7 13.6 4.2 8.8 7.2 8.8 6.8 7.5 4.7 9.9 4.9 9.0 33.3 6.0 10.5 12.0 4.0 17.7 5.4 9.6 5.9 16.0 6.6 4.9 12.6 9.1 12.0 3.2 14.3 11.2 2.2 2.8 4.2 1.1 1.4 8.3 7.2 9.6 3.9 5.3 1.7 5.9 6.3 6.6 3.3 4.9 3.3 4.0 10.6 6.4 1.0 2.9 2.4 3.1 9.5 4.6 17.2 3.4 7.4 4.8 6.2 28.3 4.1 1.4 6.6 1.2 9.0 23.4 3.9 3.6 0.6 6.6 17.1 9.8 4.5 12.6 2.7 5.4 4.4 1.1 3.2 9.5 14.7 0.3 6.5 1.6 7.0 9.6 8.4 10.0 3.5 4.3 8.2 3.2 8.2 9.1 5.2 11.6 2.7 2.0 5.7 2.0 2.2 1.9 1.7 2.4 2.2 1.0 3.2 4.2 3.3 11.2 2.8 1.3 14.3 2.7 1.1 9.3 11.9 24.1 10.6 10.4 6.0 5.1 4.7 6.8 5.9 ST3GAL3 "MRT12, SIAT6" ENSG00000126091 "ST3 beta-galactoside alpha-2,3-sialyltransferase 3" Q11203 1 43705824-43931165 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 71.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051102 Uncertain "Intracellular and membrane" "HPA051102: AB_2681344" "unprognostic (8.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (3.20e-1)" "unprognostic (9.72e-2)" "unprognostic (7.01e-2)" "unprognostic (4.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.38e-3)" "unprognostic (7.00e-2)" "unprognostic (3.68e-3)" "unprognostic (1.67e-2)" "unprognostic (1.30e-1)" "unprognostic (4.35e-1)" "unprognostic (6.60e-2)" 11.6 9.0 13.0 8.9 16.5 9.9 12.8 15.5 20.4 9.0 10.3 9.0 8.0 3.2 10.8 10.7 8.7 8.3 7.2 16.9 12.8 13.9 6.7 9.1 7.2 7.6 12.0 10.4 13.3 7.5 6.9 10.9 6.7 11.6 8.8 5.1 9.0 8.0 13.9 71.5 7.4 3.8 15.9 7.7 6.0 5.9 14.5 10.3 3.2 8.1 17.8 4.8 8.1 7.0 7.1 7.0 5.8 4.2 4.7 7.6 6.1 2.4 1.9 14.4 6.8 11.3 14.3 1.8 9.4 19.6 8.8 8.5 1.7 4.0 4.6 4.9 12.1 2.4 1.3 6.2 10.6 5.3 3.2 8.7 6.1 4.6 9.5 3.9 4.4 7.6 4.7 6.4 14.1 6.9 5.1 8.5 16.3 1.6 4.0 7.5 5.7 5.0 6.8 1.9 3.1 7.1 1.6 5.8 8.6 3.7 1.4 8.2 2.2 19.0 6.6 5.3 2.5 8.6 9.5 6.8 3.9 4.3 7.8 9.5 9.8 2.9 4.2 2.5 6.8 2.5 6.1 4.5 4.4 5.1 3.0 7.1 7.6 5.7 5.8 4.7 3.7 7.0 5.2 6.1 13.0 16.5 15.5 20.4 12.8 13.9 12.0 10.4 11.6 10.3 ST3GAL4 "CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, STZ" ENSG00000110080 "ST3 beta-galactoside alpha-2,3-sialyltransferase 4" Q11206 11 126355640-126440344 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 74.2" "Cell line enhanced" "Detected in many" "SK-MEL-30: 44.7;WM-115: 101.5" "Cancer enhanced" "Detected in all" "melanoma: 57.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 31.3;neutrophil: 22.8;plasmacytoid DC: 29.6" "Group enriched" "Detected in many" 11 "dendritic cells: 29.6;granulocytes: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049827 Approved "Intracellular and membrane" "HPA049827: " "unprognostic (8.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.92e-2)" "unprognostic (6.93e-2)" "unprognostic (8.33e-2)" "unprognostic (3.80e-2)" "unprognostic (2.71e-3)" "unprognostic (1.90e-3)" "unprognostic (2.62e-1)" "unprognostic (1.80e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (2.79e-2)" "unprognostic (1.28e-1)" "unprognostic (8.36e-3)" "unprognostic (8.78e-3)" 7.8 38.0 6.2 6.5 12.2 7.8 12.9 4.0 13.6 8.3 27.0 26.4 5.1 2.0 6.0 42.1 25.5 6.0 11.4 26.5 8.6 6.2 16.7 11.5 12.4 9.0 18.7 9.0 39.3 5.1 0.8 5.6 74.2 13.8 12.1 31.5 35.7 14.4 8.0 1.9 5.6 3.8 11.0 23.0 17.0 4.8 18.8 12.4 2.2 6.1 4.3 10.1 21.1 13.2 0.1 29.6 31.3 2.6 1.2 1.7 1.8 4.8 4.0 3.2 2.7 9.4 7.8 7.9 5.6 10.9 5.1 3.5 2.3 8.4 1.4 4.3 8.9 7.6 6.6 3.7 4.0 5.2 1.9 12.4 10.1 2.7 6.1 14.8 25.4 6.2 5.9 7.7 12.2 6.8 7.7 3.7 6.3 20.0 4.7 15.2 2.0 26.5 4.8 9.8 0.6 1.1 14.0 6.0 3.8 6.2 37.7 44.7 13.1 9.8 2.5 12.3 2.8 8.7 10.6 0.3 0.8 0.7 5.6 22.8 101.5 31.3 1.6 0.2 1.7 2.6 1.6 0.1 0.6 1.1 6.6 0.0 0.1 0.8 22.8 1.2 1.2 29.6 0.0 1.8 6.2 12.2 4.0 13.6 8.6 6.2 18.7 9.0 13.8 12.4 ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 40.1" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;RT4: 21.7;SK-MEL-30: 17.9;U-266/84: 18.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles Vesicles "HPA034708: AB_10601594, HPA040425: , HPA068928: " "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavourable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favourable (4.99e-4)" "prognostic favourable (4.48e-4)" 8.0 40.1 15.3 7.2 18.5 4.1 4.2 9.9 34.9 3.3 3.8 18.8 0.0 2.7 8.0 2.9 2.9 4.9 11.8 2.1 14.8 12.0 2.4 7.0 18.0 11.5 14.0 13.4 7.2 2.9 1.5 7.4 24.1 18.1 4.8 5.0 18.7 4.8 2.2 9.5 5.0 3.4 6.2 18.0 11.1 4.1 9.0 13.4 5.5 36.7 0.4 6.9 30.9 7.8 2.5 1.1 1.3 6.1 1.4 1.8 0.5 0.1 12.5 1.1 25.6 10.6 5.7 3.8 2.7 8.4 2.7 2.4 0.2 9.1 0.3 0.0 4.6 0.4 1.6 2.9 3.3 0.1 1.5 0.2 0.5 0.4 8.5 0.1 3.7 3.2 0.4 1.0 0.4 6.4 0.3 14.2 8.6 0.8 0.8 1.4 0.1 0.0 1.6 8.1 5.0 1.4 21.7 1.8 1.8 0.1 0.0 17.9 0.1 0.5 2.1 0.0 1.3 0.0 0.2 14.3 18.9 0.2 2.0 2.6 12.9 0.9 1.8 0.1 1.4 6.1 1.8 2.5 0.8 0.9 1.1 1.5 0.7 0.8 1.3 1.4 5.1 0.4 0.3 0.5 15.3 18.5 9.9 21.9 14.8 12.0 14.0 13.4 18.1 13.4 ST6GAL1 SIAT1 ENSG00000073849 "ST6 beta-galactoside alpha-2,6-sialyltransferase 1" P15907 3 186930485-187078553 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.4" "Cell line enhanced" "Detected in many" "Daudi: 31.9;U-266/70: 101.7;U-266/84: 130.0;U-698: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015018, CAB016122" Supported "Secreted to blood" 15000000 580000 "CAB015018: AB_629203, CAB016122: AB_627178" "unprognostic (5.85e-3)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (2.64e-1)" "unprognostic (2.44e-2)" "unprognostic (1.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (3.99e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" "unprognostic (7.30e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-2)" 10.6 6.5 11.8 16.7 15.4 4.0 10.5 2.8 11.8 19.1 11.4 22.7 4.2 4.3 8.6 4.3 4.4 8.6 5.7 10.6 10.7 7.6 19.1 161.4 10.9 27.6 18.2 7.6 4.5 4.1 20.5 5.7 5.5 13.7 19.5 14.2 5.4 17.7 4.6 5.7 4.5 12.6 5.8 22.3 27.0 8.5 2.4 15.1 19.4 19.4 4.0 41.6 13.2 14.3 33.6 4.6 6.9 8.9 8.5 29.3 16.9 0.7 0.7 3.0 2.2 0.2 0.0 4.7 0.2 0.4 0.1 0.3 0.2 0.2 31.9 2.6 0.0 1.4 18.8 1.9 0.2 1.5 0.8 1.2 0.1 15.5 0.1 3.0 10.0 0.2 4.1 0.0 1.7 11.0 6.4 3.0 0.9 1.3 2.2 2.1 6.7 0.9 5.1 0.0 1.0 1.4 0.0 4.9 0.5 0.1 3.6 8.3 5.3 2.1 4.2 0.0 0.4 0.0 0.3 101.7 130.0 47.4 0.1 6.0 11.0 6.9 2.7 1.1 16.5 5.2 15.0 32.7 18.2 13.8 4.6 33.6 29.3 20.2 1.3 8.5 8.9 4.2 14.2 16.9 11.8 15.4 2.8 11.8 10.7 7.6 18.2 7.6 13.7 15.1 ST6GAL2 "KIAA1877, SIAT2, St6gal2, St6GalII" ENSG00000144057 "ST6 beta-galactoside alpha-2,6-sialyltransferase 2" Q96JF0 2 106801600-106887108 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;thyroid gland: 34.0" "Cell line enhanced" "Detected in some" "A549: 5.7;NTERA-2: 4.9;PC-3: 6.5;RPMI-8226: 10.2;SCLC-21H: 6.8;U-138 MG: 8.3;U-266/70: 10.9" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 16.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014459 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA014459: AB_1857528" "unprognostic (2.08e-1)" "unprognostic (5.80e-2)" "unprognostic (1.55e-1)" "unprognostic (4.63e-2)" "unprognostic (6.44e-3)" "unprognostic (1.62e-1)" "unprognostic (2.35e-2)" "unprognostic (1.10e-2)" "unprognostic (1.29e-4)" "unprognostic (4.56e-3)" "unprognostic (7.04e-2)" "unprognostic (1.84e-2)" "unprognostic (7.01e-4)" "unprognostic (4.70e-4)" "unprognostic (4.06e-2)" "unprognostic (2.83e-1)" "unprognostic (2.07e-2)" 1.2 0.7 14.1 0.7 5.6 1.5 1.3 2.3 16.7 2.1 1.5 4.1 1.7 0.7 3.7 1.9 2.7 1.2 12.7 1.9 5.4 4.0 1.1 3.4 1.2 0.9 3.8 7.1 0.9 0.5 0.5 0.3 2.3 4.2 1.6 3.3 0.0 1.6 1.6 0.7 1.3 0.7 2.8 1.9 0.6 0.9 7.9 1.5 0.0 34.0 1.6 0.8 1.5 1.4 0.7 0.6 1.8 0.5 1.0 0.7 0.5 0.0 5.7 3.2 0.1 0.0 0.0 0.1 0.3 0.0 1.3 0.4 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 4.9 6.5 0.0 0.0 10.2 0.2 0.0 6.8 4.4 0.0 0.1 0.0 0.0 0.1 0.0 8.3 0.1 0.2 0.0 10.9 0.2 0.1 0.0 0.0 0.0 1.4 0.5 0.4 0.6 0.3 0.5 0.4 0.4 0.5 0.2 0.7 0.5 0.7 1.8 1.0 0.3 0.6 0.5 0.5 14.1 5.6 2.3 14.8 5.4 4.0 3.8 7.1 4.2 1.5 ST6GALNAC1 "SIAT7A, ST6GalNAcI" ENSG00000070526 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1" Q9NSC7 17 76624761-76643838 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 69.4" "Cell line enhanced" "Detected in some" "EFO-21: 6.1;HaCaT: 6.8;HEL: 10.9;K-562: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 11.2;naive CD4 T-cell: 4.2" "Lineage enriched" "Detected in single" 25 "T-cells: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014767, HPA014975" Enhanced Approved "Nucleoplasm,Golgi apparatus" 1200000 "Golgi apparatus" Nucleoplasm "HPA014767: , HPA014975: AB_1857529" "unprognostic (4.59e-2)" "unprognostic (8.60e-3)" "unprognostic (5.32e-3)" "unprognostic (1.86e-3)" "unprognostic (6.31e-3)" "prognostic favourable (2.54e-5)" "unprognostic (1.39e-2)" "unprognostic (1.63e-2)" "unprognostic (2.45e-1)" "unprognostic (2.58e-2)" "unprognostic (8.64e-3)" "unprognostic (2.81e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (5.87e-3)" "unprognostic (5.58e-2)" 1.4 0.3 1.2 13.9 2.6 0.7 1.3 0.8 3.2 20.4 50.9 3.1 0.3 19.8 6.3 1.8 19.6 1.5 26.6 4.1 1.6 1.3 0.4 1.1 5.7 1.1 1.8 1.2 2.0 1.1 0.1 0.4 1.7 3.7 2.6 69.4 0.1 20.8 1.4 0.9 0.6 49.0 1.9 1.5 6.0 23.9 4.0 0.6 0.0 0.5 4.5 21.6 1.9 2.6 0.0 0.0 0.4 0.0 0.0 11.2 1.1 0.1 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 6.1 0.0 6.8 0.0 1.8 0.0 0.0 0.0 10.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 32.6 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 11.2 0.2 0.0 0.0 4.2 0.0 0.4 0.0 0.0 0.0 1.4 1.1 1.2 2.6 0.8 3.2 1.6 1.3 1.8 1.2 3.7 0.6 ST6GALNAC4 "SIAT3C, SIAT7D, ST6GALNACIV" ENSG00000136840 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4" Q9H4F1 9 127907886-127917038 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 58.8;pancreas: 61.0" "Cell line enhanced" "Detected in many" "HDLM-2: 34.9;RPMI-8226: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "plasmacytoid DC: 58.8" "Lineage enriched" "Detected in many" 9 "dendritic cells: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009042 Approved "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA009042: AB_1079963" "unprognostic (2.05e-3)" "unprognostic (2.32e-1)" "unprognostic (2.22e-1)" "unprognostic (1.53e-2)" "unprognostic (3.18e-1)" "unprognostic (2.32e-1)" "prognostic unfavourable (8.63e-7)" "unprognostic (1.62e-2)" "unprognostic (4.26e-1)" "prognostic unfavourable (5.12e-4)" "unprognostic (1.04e-1)" "unprognostic (3.04e-1)" "prognostic unfavourable (8.39e-4)" "unprognostic (1.30e-3)" "unprognostic (2.72e-1)" "unprognostic (2.64e-2)" "unprognostic (2.03e-2)" 8.0 7.8 5.6 7.9 5.6 26.2 12.1 9.8 8.5 9.2 9.3 4.8 28.9 11.7 8.7 9.6 6.9 8.7 12.2 18.4 5.2 3.4 9.4 5.0 13.5 9.7 4.2 4.7 14.9 61.0 2.4 9.4 4.3 4.8 6.1 5.4 4.8 9.3 30.0 12.6 4.0 9.7 6.1 3.9 18.2 7.2 4.3 4.7 4.7 6.3 5.9 12.5 8.9 8.3 6.7 58.8 0.8 3.2 4.3 3.4 2.4 3.1 5.4 1.4 6.9 9.7 7.4 1.0 5.5 6.1 5.6 3.3 3.0 5.8 20.1 8.4 6.8 7.7 2.8 5.8 0.9 34.9 2.4 6.4 17.2 11.4 11.9 0.5 6.7 9.1 6.2 5.0 4.5 14.9 4.6 13.5 2.7 1.4 1.2 0.7 1.6 13.3 6.0 3.6 49.4 5.7 0.1 11.8 2.6 8.0 17.3 1.0 3.5 4.1 10.6 4.6 5.3 14.3 8.6 21.9 11.3 6.3 9.2 2.8 0.6 0.8 2.1 0.0 2.9 1.9 3.3 6.7 1.8 3.4 2.8 4.9 2.3 3.1 0.2 4.3 3.2 58.8 3.3 2.4 5.6 5.6 9.8 8.5 5.2 3.4 4.2 4.7 4.8 4.7 ST8SIA1 "SIAT8, SIAT8A" ENSG00000111728 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1" Q92185 12 22063773-22437041 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell line enhanced" "Detected in some" "AF22: 9.0;ASC TERT1: 6.0;RPTEC TERT1: 4.6;SK-MEL-30: 8.3;WM-115: 8.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 5 "granulocytes: 1.2;T-cells: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026775 Approved "HPA026775: AB_1857534" "unprognostic (1.98e-1)" "unprognostic (5.76e-3)" "unprognostic (1.79e-1)" "unprognostic (9.58e-2)" "unprognostic (2.89e-1)" "unprognostic (6.44e-3)" "unprognostic (1.76e-2)" "unprognostic (1.07e-2)" "unprognostic (3.07e-1)" "unprognostic (1.99e-1)" "unprognostic (6.37e-3)" "unprognostic (2.80e-2)" "unprognostic (1.07e-8)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (5.28e-2)" "unprognostic (3.16e-2)" 1.7 7.6 7.0 5.3 6.2 2.3 5.9 20.2 13.0 3.5 5.4 2.3 2.3 0.4 4.5 1.4 3.0 2.3 2.4 4.4 7.6 8.5 1.1 0.6 3.8 8.6 7.6 6.5 2.6 1.2 7.2 0.6 0.4 9.4 6.6 3.5 1.5 3.2 4.4 1.0 4.3 2.1 6.3 10.9 2.7 2.1 1.0 4.8 0.2 1.4 0.5 9.2 6.7 3.1 0.3 0.2 1.2 0.2 0.3 3.0 0.6 0.0 0.5 9.0 0.0 1.4 6.0 0.9 0.0 0.0 0.1 0.4 0.3 0.1 1.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 0.0 1.1 0.1 0.1 0.0 0.3 0.1 0.5 0.9 0.1 0.9 0.2 0.0 0.6 0.2 0.0 1.2 0.3 2.3 0.0 0.0 0.2 0.2 4.6 0.0 0.1 0.2 0.0 0.1 8.3 0.7 0.1 0.0 0.7 0.9 0.1 1.4 0.7 0.5 0.7 1.4 0.1 8.9 1.2 0.2 0.2 0.4 0.1 0.9 0.1 2.9 2.3 0.1 0.3 0.4 1.0 0.9 0.3 0.2 0.2 3.0 0.6 7.0 6.2 20.2 13.0 7.6 8.5 7.6 6.5 9.4 4.8 STAMBP AMSH ENSG00000124356 "STAM binding protein" O95630 2 73828916-73873659 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "LHCN-M2: 158.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035800, HPA035801" Uncertain Enhanced "Nucleoplasm,Plasma membrane,Cytosol" 11000 Nucleoplasm "Plasma membrane, Cytosol" "HPA035800: AB_10670591, HPA035801: " "unprognostic (1.86e-2)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "prognostic unfavourable (4.70e-5)" "unprognostic (6.13e-2)" "unprognostic (2.08e-3)" "unprognostic (3.73e-2)" "unprognostic (1.71e-1)" "unprognostic (6.58e-2)" "unprognostic (2.96e-2)" "prognostic unfavourable (5.79e-4)" "unprognostic (1.01e-1)" "unprognostic (2.29e-1)" "unprognostic (7.72e-2)" "unprognostic (2.63e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" 12.9 12.8 22.1 13.9 23.0 10.5 17.8 20.1 21.8 18.1 18.4 35.0 13.6 17.8 23.1 15.4 22.7 16.5 14.7 19.0 23.3 21.2 19.6 16.9 13.4 15.3 33.0 14.3 16.3 15.1 20.9 17.8 20.6 26.3 20.2 20.7 14.6 18.3 15.7 30.1 14.4 25.2 19.0 54.7 13.8 15.6 13.3 22.3 18.4 20.1 15.9 19.0 16.8 16.4 17.6 16.9 27.8 17.8 16.7 20.7 12.3 5.3 6.2 4.9 4.5 4.6 5.5 5.6 3.3 4.5 6.0 5.8 10.3 5.1 4.4 5.2 2.7 4.2 5.2 11.5 6.9 7.8 5.9 6.0 4.3 8.0 6.4 4.9 7.2 4.4 8.3 7.1 10.3 3.5 6.5 6.8 158.8 6.5 7.6 4.4 7.8 3.3 5.3 12.9 6.3 6.5 6.0 9.0 6.6 4.0 4.9 6.9 4.6 2.9 3.1 5.4 6.5 3.3 5.8 6.5 6.2 3.4 6.7 5.3 6.3 22.6 16.2 27.8 14.4 17.8 15.4 17.6 16.7 14.0 16.9 16.2 17.5 13.2 24.1 16.7 15.7 16.4 20.7 12.3 22.1 23.0 20.1 21.2 23.3 21.2 33.0 14.3 26.3 22.3 STAMBPL1 "ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, FLJ31524, KIAA1373" ENSG00000138134 "STAM binding protein like 1" Q96FJ0 10 88879734-88975153 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 18.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040202 Uncertain Approved "Plasma membrane" "Plasma membrane" "HPA040202: AB_10805708" "unprognostic (2.73e-1)" "unprognostic (1.95e-1)" "unprognostic (7.56e-2)" "unprognostic (4.25e-2)" "unprognostic (6.46e-2)" "unprognostic (6.27e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-2)" "unprognostic (4.67e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (6.57e-2)" "prognostic unfavourable (1.08e-5)" "unprognostic (4.41e-2)" "unprognostic (4.06e-2)" "unprognostic (1.50e-1)" "unprognostic (4.40e-3)" 3.9 15.9 3.7 6.8 5.1 2.8 2.1 12.4 8.9 2.0 5.8 3.4 1.5 4.5 2.7 1.5 2.7 1.2 2.9 4.8 3.3 3.4 1.5 1.7 2.9 11.3 2.6 14.8 8.5 1.8 2.2 6.6 1.5 4.1 1.9 8.0 1.5 1.5 1.5 1.5 3.4 6.1 1.8 3.1 6.0 3.1 18.6 3.2 1.5 1.5 1.5 9.5 3.9 2.7 10.5 15.2 4.3 0.6 13.1 14.7 4.5 6.7 8.0 0.5 0.3 8.0 15.3 0.0 14.2 14.0 9.1 8.2 0.3 12.9 8.2 1.0 7.7 3.3 2.0 2.9 9.3 7.3 5.0 2.1 5.7 0.4 5.4 9.0 2.9 5.5 0.7 15.3 4.9 0.2 0.0 3.7 24.5 1.4 15.1 10.8 3.0 6.2 1.5 6.0 1.8 3.5 2.6 4.6 5.5 1.8 0.6 16.1 1.0 1.9 2.0 8.1 5.9 9.8 8.8 8.7 8.2 7.6 8.9 9.2 7.7 4.3 0.6 4.2 6.3 0.6 8.2 10.5 9.2 7.9 0.9 7.0 9.9 5.9 0.9 13.1 0.3 15.2 14.7 4.5 3.7 5.1 12.4 8.9 3.3 3.4 2.6 14.8 4.1 3.2 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042073-172188386 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Cell line enhanced" "Detected in all" "WM-115: 51.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 27.5" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" 24000 "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: " "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favourable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavourable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 15.0 4.7 2.6 25.8 4.4 38.3 13.5 27.5 3.0 3.6 5.0 4.8 3.4 4.7 4.4 4.4 3.6 4.2 11.0 9.0 2.4 2.5 5.3 4.5 15.4 40.9 5.4 1.9 3.5 4.1 2.5 3.7 16.2 4.5 4.3 4.0 5.6 7.8 2.5 3.1 9.0 12.2 5.7 4.6 33.0 6.2 13.1 3.5 20.6 4.6 3.1 23.7 9.5 11.3 5.0 10.3 22.3 30.8 7.4 18.0 15.6 7.7 7.2 4.5 6.7 5.2 6.5 11.5 10.1 8.4 7.3 6.8 3.7 10.2 9.3 5.4 12.4 9.0 2.0 12.3 4.8 12.2 3.3 11.2 3.0 2.1 7.5 11.3 13.3 6.4 2.6 9.9 8.3 6.3 1.0 13.1 5.1 12.4 8.1 25.5 1.8 5.7 13.4 3.5 6.2 3.0 9.8 3.0 3.7 5.8 8.1 27.6 2.9 24.0 8.7 8.2 4.1 5.7 5.4 11.1 16.3 5.9 10.8 17.5 51.5 7.1 10.8 10.0 18.0 21.4 13.3 5.0 9.4 12.8 10.3 4.4 5.6 9.6 22.3 7.4 30.8 3.2 12.2 15.6 2.6 4.4 27.5 3.0 2.4 2.5 5.4 1.9 4.5 3.5 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228435 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: " "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favourable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favourable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 13.4 13.7 13.5 11.8 12.4 19.3 16.7 17.8 16.0 12.2 16.1 8.3 19.8 18.1 10.8 8.7 15.1 10.0 11.8 15.3 12.6 9.8 10.7 22.1 9.4 12.5 9.7 10.4 11.0 16.8 10.7 11.6 12.2 9.9 12.2 5.3 11.9 16.0 12.2 49.2 16.8 18.0 7.7 7.6 16.9 15.5 59.8 7.5 11.8 12.4 14.5 19.0 11.4 9.8 2.7 1.9 11.7 6.3 1.9 1.8 0.5 21.1 10.2 7.8 14.7 7.4 6.7 16.5 10.3 10.8 9.7 10.4 8.3 14.8 13.9 11.5 10.8 13.7 7.6 15.9 3.0 25.9 18.7 14.2 0.6 10.5 15.9 14.2 23.8 12.2 11.6 7.5 11.1 9.7 26.5 19.1 5.5 15.8 13.7 14.4 14.9 12.6 21.7 8.3 15.5 8.8 15.5 18.1 13.0 0.0 7.7 11.1 12.1 23.4 13.1 10.1 11.4 19.7 16.4 37.6 15.8 10.4 10.0 19.0 10.3 2.0 4.2 4.5 0.6 6.0 0.4 2.7 1.0 1.8 1.9 1.0 1.0 0.9 11.7 1.9 6.3 1.0 0.7 0.5 13.5 12.4 17.8 16.0 12.6 9.8 9.7 10.4 9.9 7.5 STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Approved Cytosol Cytosol "HPA029450: AB_10603118" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (5.84e-2)" "prognostic favourable (6.09e-4)" "unprognostic (6.21e-2)" "unprognostic (5.55e-2)" "unprognostic (4.98e-3)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (4.39e-3)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" 10.2 19.0 15.7 12.8 20.3 13.3 14.6 8.8 21.0 11.5 16.2 15.2 20.5 17.2 11.4 22.1 16.0 18.3 15.5 13.0 14.5 11.9 19.5 30.1 11.4 24.6 14.2 13.2 13.2 24.5 16.5 15.1 14.0 13.3 14.3 13.7 12.8 19.0 16.3 9.9 12.2 14.2 11.5 12.3 15.9 16.8 18.9 12.7 27.2 19.8 12.8 17.0 12.9 10.3 7.9 7.8 5.8 7.6 14.5 11.2 9.7 7.3 9.6 8.4 7.2 21.2 20.7 9.7 9.5 13.1 8.1 8.1 11.2 16.4 4.2 13.3 15.7 7.6 9.8 15.7 4.3 10.4 11.4 9.6 8.7 9.6 19.2 9.1 11.2 22.0 25.3 11.1 29.4 9.8 11.9 11.6 13.8 13.5 9.9 19.8 7.9 5.9 9.3 9.5 12.4 16.8 8.5 6.8 8.7 3.4 13.5 19.3 14.1 19.2 7.5 11.0 7.8 8.9 9.0 14.3 6.1 10.1 12.2 9.6 9.6 2.0 7.6 5.8 6.0 4.2 6.8 7.8 7.5 11.2 7.8 7.9 7.8 10.0 5.2 14.5 3.6 6.7 8.4 9.7 15.7 20.3 8.8 21.0 14.5 11.9 14.2 13.2 13.3 12.7 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43626786 "Enzymes, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 43.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "HPA018138, HPA037979" Uncertain Approved "Nuclear speckles,Plasma membrane" "Nuclear speckles" "Plasma membrane" "HPA018138: , HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 7.1 10.1 6.1 43.3 8.2 20.2 8.4 7.9 7.2 4.8 9.3 3.7 2.0 6.1 5.3 4.2 10.1 4.7 8.6 17.7 5.7 5.6 6.7 8.1 15.2 36.6 6.6 2.6 7.3 14.3 1.5 6.3 37.2 5.7 6.2 5.3 3.6 8.6 3.4 10.7 4.8 12.3 5.8 5.3 27.8 11.0 9.0 2.8 30.1 7.3 6.8 37.7 10.3 8.1 10.8 1.4 11.5 0.9 12.7 11.4 2.9 4.5 5.7 5.2 3.5 6.5 8.6 2.1 16.5 17.8 9.0 9.2 4.9 3.3 7.3 26.0 13.7 9.4 3.9 21.9 12.6 18.0 4.4 6.5 4.3 6.1 4.8 11.2 4.4 7.0 25.8 11.9 10.9 16.8 7.6 25.2 10.3 2.1 18.2 5.2 8.0 18.7 6.3 3.3 14.5 15.7 3.4 2.8 6.3 7.4 3.4 4.8 4.0 5.7 16.8 19.6 7.5 11.6 18.4 15.3 7.6 10.6 19.9 9.9 31.2 0.7 0.4 11.5 5.8 0.2 5.8 10.8 6.1 9.7 0.3 10.1 11.4 10.2 6.4 12.7 0.9 1.4 3.2 2.9 6.1 8.2 7.9 5.9 5.7 5.6 6.6 2.6 5.7 2.8 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133566-196176503 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 62.0;bone marrow: 103.4;lymphoid tissue: 72.2" "Cell line enhanced" "Detected in many" "Daudi: 35.5;HMC-1: 36.0;Karpas-707: 33.4;U-698: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebellum: 71.1" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavourable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 21.0 4.1 3.2 42.8 3.8 103.4 10.1 3.2 3.3 8.2 18.8 1.1 3.8 8.5 3.4 3.9 8.9 6.3 8.6 5.7 3.3 2.2 7.2 2.9 26.2 53.7 2.3 1.8 3.1 5.0 0.7 3.8 6.5 1.7 6.8 5.7 3.5 16.7 6.1 3.4 10.9 31.8 5.3 2.7 59.3 6.0 4.6 1.4 72.2 7.5 7.0 56.2 11.3 6.0 16.9 13.6 62.0 27.0 10.3 28.4 19.0 3.1 2.2 3.3 1.2 14.7 5.6 3.7 7.6 11.4 8.3 8.7 6.6 1.1 35.5 7.0 4.3 2.2 1.4 3.2 10.2 6.2 3.8 3.3 2.8 0.6 4.4 13.4 36.0 7.1 3.2 10.3 5.4 3.4 2.6 33.4 20.6 1.7 17.4 30.4 1.9 5.1 2.9 20.3 10.7 4.9 7.5 1.2 1.3 1.9 1.9 1.6 1.3 7.0 4.1 8.1 4.0 5.8 4.2 13.7 22.2 38.7 6.1 4.6 3.6 35.9 19.7 40.2 12.0 20.7 15.3 13.3 21.5 14.5 13.6 16.9 28.4 23.1 62.0 10.3 27.0 9.7 18.5 19.0 3.2 3.8 3.2 3.3 3.3 2.2 2.3 1.8 1.7 1.4 STK19 "D6S60, G11, RP1" ENSG00000204344 "Serine/threonine kinase 19" P49842 6 31971091-31982821 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 4.8;REH: 4.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031510, HPA031511, HPA068559" Uncertain Supported "Nuclear speckles" "Nuclear speckles" "HPA031510: AB_10603119, HPA031511: AB_2673915, HPA068559: " "unprognostic (1.65e-1)" "unprognostic (2.30e-1)" "unprognostic (3.31e-1)" "unprognostic (1.86e-1)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavourable (1.18e-4)" "unprognostic (3.95e-2)" "unprognostic (2.76e-3)" "unprognostic (2.25e-2)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.40e-1)" "unprognostic (4.10e-1)" 6.4 8.2 3.8 4.3 6.5 2.9 4.0 9.9 6.3 5.7 6.6 5.5 4.2 2.2 6.0 5.5 5.3 3.5 5.3 3.6 5.0 3.5 3.9 6.6 4.1 2.5 4.3 7.5 5.7 12.4 4.7 4.6 6.3 4.0 6.2 2.7 5.6 2.9 6.7 6.1 6.8 2.6 5.9 3.7 7.0 6.3 7.9 4.2 2.6 4.7 4.1 3.8 4.4 4.2 2.1 2.7 0.4 3.8 0.9 1.1 0.5 0.0 0.3 0.0 1.1 2.9 1.7 0.0 2.3 0.3 0.5 1.1 0.0 1.9 1.5 0.6 1.2 2.0 0.0 0.6 0.9 4.8 0.9 3.6 0.9 0.2 1.4 3.7 0.0 1.5 0.1 0.8 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.6 0.0 4.4 2.4 1.1 0.0 0.0 1.0 0.9 0.3 0.6 0.2 1.7 0.0 0.0 0.0 1.1 1.1 0.0 0.1 2.3 0.1 1.9 0.6 0.1 0.0 3.8 0.1 0.6 1.4 0.7 2.1 0.9 0.1 2.7 1.0 1.1 0.5 0.4 0.9 1.4 1.5 0.1 0.5 3.8 6.5 9.9 6.3 5.0 3.5 4.3 7.5 4.0 4.2 STK24 "MST-3, MST3, MST3B, STE20, STK3" ENSG00000102572 "Serine/threonine kinase 24" Q9Y6E0 13 98445185-98577940 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026435, HPA026502" Enhanced Supported Nucleoli,Cytosol 2800000 "Nucleoli, Cytosol" "HPA026435: AB_1854151, HPA026502: AB_1854152" "unprognostic (3.49e-2)" "unprognostic (2.39e-2)" "unprognostic (1.78e-1)" "unprognostic (3.44e-2)" "unprognostic (2.86e-1)" "unprognostic (3.25e-2)" "unprognostic (9.67e-3)" "prognostic unfavourable (6.23e-6)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.81e-4)" "unprognostic (9.62e-2)" "prognostic favourable (6.91e-5)" "unprognostic (3.10e-2)" "unprognostic (4.49e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-2)" 28.6 14.2 15.0 29.7 16.9 19.1 34.8 12.2 21.0 36.3 37.4 12.1 23.0 31.9 24.6 26.5 68.4 20.4 41.3 30.0 14.7 12.8 30.5 14.2 23.9 31.2 10.6 10.1 20.0 20.6 12.4 13.9 38.4 14.7 28.3 28.8 36.8 30.8 21.6 18.8 60.6 67.9 34.8 9.2 31.7 30.2 22.1 7.6 38.2 28.2 41.6 48.5 39.2 45.4 8.1 11.2 11.4 13.4 1.5 13.7 6.7 36.0 11.2 20.0 18.5 30.8 18.4 28.4 16.9 23.8 23.7 23.2 32.9 49.0 25.7 8.6 21.1 32.7 18.5 37.2 22.7 64.0 9.5 27.4 14.4 18.8 43.5 27.6 19.5 11.9 59.5 18.6 54.8 20.3 9.9 17.8 15.5 15.7 20.6 11.4 17.9 8.5 26.1 12.3 13.9 22.8 32.6 11.7 16.8 10.7 17.2 22.8 20.8 26.9 27.4 15.1 11.0 12.3 19.4 17.4 9.1 9.6 23.5 16.7 24.8 5.8 13.4 6.1 6.1 10.6 7.2 6.6 11.4 8.7 11.2 8.1 7.8 6.1 11.4 1.5 12.7 7.5 13.7 6.7 15.0 16.9 12.2 21.0 14.7 12.8 10.6 10.1 14.7 7.6 STK25 "SOK1, YSK1" ENSG00000115694 "Serine/threonine kinase 25" O00506 2 241492674-241509730 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 164.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047147 Uncertain "HPA047147: AB_10966137" "unprognostic (1.75e-1)" "unprognostic (8.29e-2)" "prognostic unfavourable (6.03e-4)" "unprognostic (3.42e-2)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (3.91e-8)" "unprognostic (6.16e-2)" "unprognostic (7.15e-3)" "unprognostic (1.11e-1)" "unprognostic (2.58e-3)" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-1)" "unprognostic (3.19e-1)" "unprognostic (4.58e-1)" 17.8 13.6 22.3 14.2 26.0 16.3 12.9 22.3 35.3 16.4 17.1 17.0 13.0 14.6 17.7 15.9 19.3 15.4 16.7 19.0 19.4 20.0 17.3 13.5 13.4 13.5 16.3 20.4 17.5 19.2 18.9 17.1 15.6 16.4 15.1 12.9 13.5 14.2 17.6 164.2 15.3 14.2 17.3 12.6 15.8 16.1 16.8 14.4 15.2 20.0 24.6 12.6 14.6 16.6 15.0 13.6 13.7 16.4 21.5 19.9 10.6 18.3 11.7 23.4 29.0 28.8 20.1 36.0 30.7 20.7 23.4 26.8 13.0 16.2 7.0 8.7 40.9 15.7 32.9 33.4 28.5 26.2 34.5 19.6 24.8 33.6 26.1 11.9 15.1 28.9 24.0 22.6 18.2 52.8 30.2 6.2 42.8 19.3 17.6 18.5 32.6 16.8 29.7 29.8 10.4 20.6 15.6 39.3 18.0 14.9 11.3 19.2 9.0 21.1 61.5 17.7 21.7 20.3 21.7 12.9 2.9 11.9 17.1 9.8 20.0 13.7 14.8 11.5 16.9 13.4 15.5 14.5 15.5 17.5 13.6 15.0 12.0 11.6 5.5 21.5 16.4 10.7 19.9 10.6 22.3 26.0 22.3 35.3 19.4 20.0 16.3 20.4 16.4 14.4 STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023265-132075943 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: " "unprognostic (6.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-3)" "unprognostic (4.42e-1)" "unprognostic (1.03e-2)" "prognostic unfavourable (6.82e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-3)" "unprognostic (2.49e-1)" "prognostic unfavourable (6.87e-5)" "unprognostic (4.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" 5.4 1.4 1.1 13.5 5.1 25.9 3.3 3.8 1.1 18.0 6.4 0.3 34.8 3.7 42.3 29.6 11.7 6.0 5.2 1.9 1.2 2.3 3.5 3.2 6.7 12.8 1.2 0.3 4.7 4.0 10.2 5.8 50.7 1.2 11.5 4.8 2.2 6.3 22.4 1.2 5.1 6.1 19.1 1.5 8.5 4.7 5.2 0.8 44.7 2.3 6.8 10.2 18.0 6.6 8.4 6.2 26.4 11.6 22.0 13.3 10.2 9.0 3.1 0.3 0.0 1.5 1.4 20.7 0.3 1.1 0.1 0.1 8.3 8.2 12.3 5.6 2.0 10.3 23.0 14.4 0.0 10.6 18.8 17.7 7.8 7.8 1.4 37.0 1.4 2.0 8.6 0.0 9.8 4.0 7.8 11.6 3.4 7.9 38.0 34.4 18.4 1.2 27.5 11.4 15.8 9.3 14.5 7.7 8.5 5.4 4.9 0.2 6.3 9.8 0.1 3.7 4.0 11.2 13.2 8.9 14.0 13.7 3.4 40.3 1.8 26.4 5.1 16.6 13.3 6.7 13.0 8.4 9.1 11.3 6.2 7.3 11.8 12.2 10.0 22.0 11.6 2.3 4.0 10.2 1.1 5.1 3.8 1.1 1.2 2.3 1.2 0.3 1.2 0.8 STK3 "KRS1, MST2" ENSG00000104375 "Serine/threonine kinase 3" Q13188 8 98401403-98942827 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 37.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.3;granulocytes: 9.0;monocytes: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007120, CAB025316" Uncertain Approved "Intermediate filaments,Rods & Rings" "Intermediate filaments, Rods & Rings" "CAB025316: , HPA007120: AB_10601664" "unprognostic (7.88e-3)" "unprognostic (1.96e-1)" "unprognostic (6.57e-2)" "prognostic unfavourable (1.53e-4)" "unprognostic (2.95e-1)" "unprognostic (1.12e-3)" "unprognostic (9.68e-3)" "prognostic unfavourable (4.25e-4)" "unprognostic (6.71e-2)" "unprognostic (9.83e-2)" "prognostic unfavourable (9.21e-5)" "unprognostic (9.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (9.72e-2)" 16.5 16.6 6.5 8.1 12.4 2.5 20.5 2.6 10.6 17.2 13.1 10.5 14.2 4.6 22.2 13.1 9.0 16.0 12.6 10.0 7.4 4.1 14.7 12.0 16.2 10.8 12.8 3.6 22.8 10.7 15.1 18.9 53.1 9.9 15.0 6.0 8.2 10.8 16.4 11.6 10.0 10.8 23.5 12.9 8.2 9.5 10.1 11.4 3.4 10.6 7.9 5.9 16.4 24.3 1.9 8.3 9.0 8.7 1.8 1.8 2.9 37.6 7.1 7.5 9.9 24.4 12.2 7.5 13.1 11.8 12.3 10.7 5.2 16.0 0.0 11.4 13.0 15.3 5.2 11.3 19.9 9.0 6.7 10.1 3.5 3.5 8.3 3.3 8.8 8.1 19.5 6.3 17.2 5.2 4.2 5.5 8.9 4.7 8.4 4.0 2.2 2.8 7.4 6.5 3.2 14.0 4.7 1.9 4.4 8.3 9.6 8.1 7.9 5.5 3.9 8.3 5.3 12.5 7.2 4.4 6.5 2.7 7.4 4.2 13.1 2.1 8.6 4.5 1.3 8.7 1.4 1.9 0.8 1.8 8.3 1.3 1.1 0.7 9.0 1.8 5.4 3.4 0.1 2.9 6.5 12.4 2.6 10.6 7.4 4.1 12.8 3.6 9.9 11.4 STK31 "SgK396, TDRD8" ENSG00000196335 "Serine/threonine kinase 31" Q9BXU1 7 23710167-23832513 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 56.0" "Cell line enriched" "Detected in some" 8 "CACO-2: 19.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023194 Enhanced "HPA023194: AB_1857590" "unprognostic (4.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (1.50e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.42e-3)" "unprognostic (2.92e-1)" "unprognostic (1.29e-6)" "unprognostic (7.83e-2)" "unprognostic (9.21e-3)" "unprognostic (1.46e-1)" "unprognostic (3.65e-1)" 0.1 0.0 0.1 0.1 0.7 0.0 0.1 0.8 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 56.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 19.7 2.4 0.0 2.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.8 0.1 0.2 0.0 0.1 0.1 0.1 0.1 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387852 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 19.7;brain: 21.1;retina: 31.9" "Group enriched" "Detected in some" 5 "RT4: 9.6;SK-MEL-30: 33.8" "Cancer enhanced" "Detected in many" "melanoma: 11.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040236 Uncertain Approved Centrosome Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 2.1 19.7 4.8 1.3 7.1 0.4 2.3 21.1 7.7 1.2 1.8 6.2 0.6 1.2 1.6 5.6 1.0 1.3 4.3 1.6 4.9 12.6 6.3 0.6 2.1 0.5 12.1 2.2 5.1 4.2 0.4 8.5 0.7 20.7 2.1 1.1 31.9 1.2 1.8 0.6 2.9 1.1 1.4 12.4 0.8 1.4 2.1 6.9 0.0 15.7 0.5 0.5 4.1 2.1 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.1 3.7 9.6 0.9 0.4 0.0 0.1 33.8 0.0 0.0 0.1 0.0 0.6 0.4 0.3 1.1 0.2 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 4.8 7.1 21.1 2.3 4.9 12.6 12.1 2.2 20.7 6.9 STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051442-5500998 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.6;lymphoid tissue: 33.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 11.5;REH: 10.1;U-2197: 18.5;WM-115: 47.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive B-cell: 1.3;plasmacytoid DC: 3.5" "Group enriched" "Detected in many" 4 "B-cells: 1.3;dendritic cells: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA058536 Approved Vesicles,Microtubules Microtubules Vesicles "HPA058536: " "unprognostic (4.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (8.12e-3)" "unprognostic (9.96e-2)" "unprognostic (1.64e-4)" "unprognostic (1.27e-1)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (8.82e-2)" "prognostic favourable (1.63e-8)" "unprognostic (8.10e-3)" "unprognostic (5.04e-2)" "unprognostic (3.62e-2)" "unprognostic (1.67e-3)" 5.2 0.8 6.0 2.1 4.8 2.3 7.3 1.0 5.8 6.0 2.1 5.2 1.6 1.2 5.7 1.6 2.3 2.5 4.7 0.9 4.5 7.6 23.6 0.5 1.3 2.8 5.3 2.2 1.2 4.9 0.8 0.8 5.1 4.2 2.3 2.2 3.0 2.9 1.9 2.1 3.6 1.6 7.0 3.9 0.6 9.5 7.1 2.9 33.6 2.8 2.1 1.9 4.2 6.1 1.3 3.5 0.0 0.5 0.0 0.0 0.0 0.0 5.7 0.3 0.0 0.2 0.4 0.0 4.0 0.5 2.7 0.1 0.0 0.0 0.0 0.8 8.1 0.0 0.6 0.0 1.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 11.5 0.0 0.0 1.4 0.0 0.0 0.8 1.7 0.0 10.1 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 2.9 0.0 1.1 18.5 0.0 0.4 0.0 0.0 0.0 0.0 47.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 6.0 4.8 1.0 5.8 4.5 7.6 5.3 2.2 4.2 2.9 STK32C "MGC23665, PKE, YANK3" ENSG00000165752 "Serine/threonine kinase 32C" Q86UX6 10 132207492-132331847 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017894 Uncertain "HPA017894: AB_1857591" "unprognostic (2.11e-1)" "unprognostic (8.40e-2)" "unprognostic (4.80e-3)" "prognostic unfavourable (1.09e-4)" "unprognostic (1.65e-2)" "unprognostic (5.52e-2)" "prognostic unfavourable (1.68e-6)" "unprognostic (2.03e-1)" "unprognostic (7.79e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.31e-6)" "unprognostic (8.65e-2)" "unprognostic (3.20e-1)" "unprognostic (5.05e-2)" "unprognostic (1.36e-1)" 6.8 8.2 23.5 6.4 23.5 6.1 7.1 8.3 31.6 4.1 4.9 6.3 6.0 5.0 4.6 15.5 3.4 9.4 7.8 7.0 17.9 12.8 6.3 4.2 7.3 8.5 9.2 16.1 5.8 7.0 6.2 6.7 4.8 7.7 4.6 4.7 3.2 5.6 5.5 11.3 7.1 4.7 4.9 7.7 10.7 4.8 26.1 8.1 8.7 4.9 3.0 6.1 4.6 3.6 5.5 14.5 25.0 11.2 3.2 4.9 3.6 31.5 20.7 6.3 16.0 9.0 11.4 1.3 6.6 5.2 8.4 10.9 4.6 22.1 7.0 5.0 7.7 7.3 9.2 2.7 8.2 4.1 14.8 4.0 21.2 21.9 11.3 3.7 15.2 8.6 10.1 7.6 8.7 7.4 7.1 4.9 9.0 9.5 4.6 14.0 4.2 15.1 5.5 4.0 2.2 11.0 5.5 16.7 13.1 4.8 4.5 9.4 5.1 8.8 4.9 7.0 6.9 8.7 5.2 9.1 1.7 17.3 15.2 3.5 3.4 25.0 10.7 9.2 3.5 11.2 4.5 3.6 2.9 4.0 14.5 5.5 3.6 2.9 1.4 3.2 9.5 8.3 4.9 3.6 23.5 23.5 8.3 31.6 17.9 12.8 9.2 16.1 7.7 8.1 STK33 ENSG00000130413 "Serine/threonine kinase 33" Q9BYT3 11 8391868-8594289 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.4" "Cell line enhanced" "Detected in many" "Daudi: 14.1;HEK 293: 12.0;Karpas-707: 13.2;SCLC-21H: 14.8;U-251 MG: 14.9;U-266/84: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 7.1;naive B-cell: 4.4" "Lineage enriched" "Detected in many" 5 "B-cells: 7.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015742, HPA056855" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "HPA015742: AB_1857592, HPA056855: " "unprognostic (2.57e-2)" "unprognostic (2.80e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (3.57e-1)" "unprognostic (1.40e-1)" "unprognostic (7.28e-2)" "unprognostic (3.85e-4)" "unprognostic (1.23e-1)" "unprognostic (8.06e-2)" "unprognostic (1.33e-3)" "unprognostic (9.46e-2)" "prognostic favourable (4.89e-6)" "unprognostic (2.39e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.90e-2)" 0.9 6.1 4.7 1.6 7.5 1.1 0.6 6.1 4.4 5.4 5.3 6.8 7.7 2.6 9.6 15.3 2.3 30.7 4.5 11.4 6.6 6.1 7.7 0.4 5.3 2.3 4.9 2.7 10.3 4.6 20.4 29.9 0.3 17.7 5.3 1.3 14.8 1.6 8.9 2.6 0.3 2.5 7.0 6.7 1.2 4.4 34.4 4.6 4.5 14.6 1.5 1.8 3.7 1.4 7.1 0.7 0.0 0.0 0.2 1.4 0.3 0.0 2.0 9.8 0.0 0.0 0.0 0.0 1.7 1.9 4.2 3.9 1.2 0.0 14.1 7.4 0.3 0.0 4.3 1.3 3.7 0.0 12.0 0.0 2.6 3.3 1.6 7.8 0.0 0.4 0.0 0.1 0.0 0.3 0.0 13.2 0.1 0.0 0.3 0.0 7.0 0.0 5.3 1.3 8.9 3.8 0.0 14.8 3.9 0.0 0.0 0.1 0.0 0.8 0.0 0.0 6.7 0.1 14.9 3.1 12.5 0.2 4.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.1 0.0 1.4 0.0 4.4 0.0 1.1 0.0 0.2 0.0 0.7 0.2 0.3 4.7 7.5 6.1 4.4 6.6 6.1 4.9 2.7 17.7 4.6 STK35 "bA550O8.2, CLIK1" ENSG00000125834 "Serine/threonine kinase 35" Q8TDR2 20 2101611-2177038 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 27.8;testis: 37.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026452, HPA051673" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA026452: , HPA051673: " "unprognostic (2.25e-2)" "unprognostic (2.97e-1)" "unprognostic (2.87e-2)" "unprognostic (1.30e-2)" "unprognostic (3.25e-1)" "unprognostic (2.28e-1)" "prognostic unfavourable (9.46e-6)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (3.05e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-1)" "unprognostic (4.39e-2)" "unprognostic (1.74e-1)" "unprognostic (4.67e-1)" "unprognostic (1.40e-1)" "unprognostic (4.99e-2)" 5.3 6.0 10.3 3.6 14.3 4.3 5.1 6.1 13.7 3.7 4.3 3.1 2.5 4.2 4.5 3.5 8.0 5.1 4.3 5.2 5.9 4.8 4.4 5.7 4.2 3.3 4.4 7.6 3.9 5.9 5.3 6.5 3.5 4.0 3.8 5.2 27.8 6.1 4.0 3.5 6.3 4.6 4.9 4.5 4.1 4.1 37.6 4.4 1.7 5.4 6.1 4.5 4.1 3.7 1.8 2.0 3.2 1.4 0.8 2.7 1.2 14.8 12.6 9.9 16.9 4.5 6.2 12.0 6.1 7.5 8.2 8.5 16.6 11.6 10.2 5.0 7.6 22.5 11.6 14.0 9.4 4.0 5.5 9.7 4.4 17.9 5.8 8.7 4.5 5.4 12.3 13.0 11.3 7.7 9.4 8.5 5.3 6.6 10.9 12.4 18.3 8.6 9.5 8.8 6.4 7.4 14.9 16.3 7.9 10.8 19.5 9.7 9.6 8.7 6.5 14.0 9.6 7.0 9.6 7.5 9.6 7.1 7.5 9.5 6.1 0.0 1.2 0.7 1.9 1.0 2.5 1.7 2.7 1.3 2.0 1.8 2.6 2.2 3.2 0.8 1.4 1.7 1.3 1.2 10.3 14.3 6.1 13.7 5.9 4.8 4.4 7.6 4.0 4.4 STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672026-218702716 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol Cytosol "HPA027409: AB_10600223, HPA027453: AB_10601893, HPA030058: AB_10601225" "unprognostic (8.11e-2)" "unprognostic (3.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "prognostic unfavourable (5.20e-4)" "unprognostic (1.55e-1)" "unprognostic (5.83e-3)" "unprognostic (9.04e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.52e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.99e-3)" 4.8 10.0 7.5 4.7 11.4 2.0 6.4 7.9 11.1 9.1 7.4 7.0 11.9 4.1 14.4 13.3 5.0 13.9 9.8 3.3 6.3 3.5 10.1 4.4 6.9 3.9 2.3 6.6 13.6 9.7 12.3 23.2 3.9 7.6 9.5 6.3 9.3 7.3 8.3 3.3 4.6 5.8 7.8 5.5 4.9 7.9 63.2 4.2 3.5 11.4 3.7 5.0 9.3 7.1 1.8 1.6 3.2 1.9 2.2 1.6 1.7 2.7 6.4 14.0 11.9 15.2 11.9 8.5 7.6 6.1 9.7 9.2 8.3 4.6 3.7 10.6 7.9 5.6 9.5 7.9 8.6 1.6 7.9 3.6 19.1 11.4 7.4 5.0 6.1 12.8 5.9 9.5 6.8 7.2 8.3 4.7 8.0 6.4 3.0 6.3 8.4 4.1 5.6 6.0 3.7 11.9 14.0 11.4 9.7 5.9 9.6 3.9 9.8 4.1 6.9 13.5 5.0 5.1 5.2 6.0 4.6 1.9 8.4 2.4 5.6 0.0 1.9 3.2 1.5 1.2 0.9 1.8 1.1 1.3 1.6 0.6 1.1 1.6 0.2 2.2 1.4 1.3 1.0 1.7 7.5 11.4 7.9 11.1 6.3 3.5 2.3 6.6 7.6 4.2 STK38 NDR ENSG00000112079 "Serine/threonine kinase 38" Q15208 6 36493892-36547470 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004673, HPA038623, HPA051324" Uncertain Approved Cytosol Cytosol "CAB004673: AB_425892, HPA038623: AB_10967059, HPA051324: " "unprognostic (3.58e-3)" "unprognostic (1.80e-2)" "unprognostic (3.07e-2)" "unprognostic (6.76e-3)" "unprognostic (8.25e-2)" "unprognostic (1.47e-2)" "unprognostic (2.88e-3)" "unprognostic (2.08e-1)" "prognostic unfavourable (9.44e-5)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (1.98e-2)" "unprognostic (3.80e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.13e-3)" 19.1 8.4 12.4 39.8 10.0 19.4 32.8 18.8 12.7 16.0 26.3 7.8 14.9 17.0 18.8 16.4 28.1 14.6 18.3 15.3 12.1 7.0 15.0 17.3 21.7 45.9 11.9 6.4 12.3 9.5 7.8 11.0 15.4 9.0 17.0 27.1 11.3 24.8 18.7 14.9 21.8 29.1 28.1 13.1 25.1 16.4 24.4 11.0 34.3 10.6 13.4 28.5 22.4 19.8 10.6 13.1 33.2 30.5 25.8 27.6 22.4 17.6 13.0 13.8 14.8 27.9 21.3 12.0 19.7 16.0 20.5 20.7 10.0 12.1 23.7 15.3 29.3 18.9 11.4 8.2 24.3 9.7 9.8 17.0 16.9 9.0 13.8 6.4 9.4 14.0 21.6 15.9 10.2 12.8 13.8 13.9 29.2 10.6 10.3 16.7 5.7 11.6 40.2 16.7 6.3 19.4 22.2 16.1 7.6 24.0 11.1 13.8 11.8 16.9 12.3 16.7 14.8 13.3 12.7 11.7 20.7 16.7 3.8 25.0 16.0 33.2 19.8 15.0 27.6 22.6 21.5 10.6 22.9 24.1 13.1 8.1 20.5 22.3 27.1 25.8 30.5 6.6 21.4 22.4 12.4 10.0 18.8 12.7 12.1 7.0 11.9 6.4 9.0 11.0 STK38L "KIAA0965, NDR2" ENSG00000211455 "Serine/threonine kinase 38 like" Q9Y2H1 12 27243968-27325959 "Enzymes, Predicted intracellular proteins" "Actin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 19.3;granulocytes: 32.2;monocytes: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038623, HPA051324" Approved Approved Cytosol Cytosol "HPA038623: AB_10967059, HPA051324: " "unprognostic (2.14e-2)" "unprognostic (1.01e-1)" "unprognostic (9.94e-2)" "unprognostic (2.43e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (4.68e-2)" "unprognostic (5.56e-2)" "unprognostic (1.56e-1)" "prognostic unfavourable (5.82e-4)" "unprognostic (1.16e-1)" "unprognostic (3.41e-2)" "unprognostic (1.09e-1)" "unprognostic (1.95e-1)" "unprognostic (5.05e-2)" "unprognostic (1.05e-2)" 21.2 8.4 11.0 14.6 10.9 10.9 27.2 9.6 14.6 13.0 26.3 5.7 9.7 8.4 23.9 18.2 16.8 14.8 18.2 30.2 10.9 7.8 8.9 8.5 10.8 7.8 11.1 11.8 9.6 8.9 30.2 15.2 10.6 11.9 15.3 15.0 6.8 14.0 10.9 9.1 10.8 14.6 52.3 17.0 7.6 15.6 7.5 10.1 10.0 8.8 10.5 9.8 21.9 22.7 4.5 19.3 32.2 13.0 4.0 4.0 5.3 4.1 5.7 14.9 6.6 6.8 4.7 11.0 2.7 3.9 1.7 2.4 7.2 3.1 9.7 6.4 2.3 7.8 6.7 4.6 2.7 56.9 5.5 6.0 6.9 3.6 5.7 14.7 7.0 5.6 4.8 6.3 8.1 13.7 7.3 7.7 3.4 3.0 9.7 16.0 17.6 8.7 3.6 17.3 7.5 2.5 8.0 2.4 7.9 12.0 7.4 4.6 3.6 5.0 5.4 5.9 5.2 8.4 7.3 2.8 2.7 10.2 2.9 6.9 2.4 6.0 13.0 22.9 4.0 11.1 2.8 4.5 3.1 3.9 19.3 3.4 3.8 3.1 32.2 4.0 8.1 8.2 4.0 5.3 11.0 10.9 9.6 14.6 10.9 7.8 11.1 11.8 11.9 10.1 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168248141 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: , HPA062802: " "prognostic favourable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavourable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 6.2 2.1 8.4 4.6 11.0 1.3 3.5 9.3 14.1 4.3 9.1 8.3 1.7 10.5 2.3 4.7 14.1 1.9 5.9 7.6 9.8 7.4 2.9 0.8 2.4 7.3 12.3 9.7 3.2 9.9 5.0 8.2 1.2 14.2 9.9 11.7 7.1 22.8 3.8 2.2 3.4 6.1 4.3 19.0 2.5 11.2 35.5 5.5 7.2 2.2 1.8 8.0 5.6 5.3 0.7 1.0 0.0 0.7 1.9 3.4 0.5 6.6 4.0 15.2 4.8 9.4 13.8 1.5 16.7 12.3 11.2 10.4 0.0 21.6 18.3 4.6 10.8 17.3 9.7 12.2 14.1 5.8 6.0 7.6 4.4 13.5 17.4 10.2 0.8 9.5 17.3 13.3 13.9 7.6 0.1 0.0 23.4 3.8 17.7 3.6 10.5 8.5 25.4 6.0 1.5 8.4 16.5 22.5 9.5 5.8 0.8 6.8 3.0 7.5 7.1 13.6 4.2 9.6 10.9 0.0 0.0 14.7 10.3 9.1 9.1 0.0 0.7 0.0 2.5 0.4 1.3 0.7 1.9 3.4 1.0 0.7 0.4 2.0 0.0 1.9 0.3 0.3 3.3 0.5 8.4 11.0 9.3 14.1 9.8 7.4 12.3 9.7 14.2 5.5 STK4 "KRS2, MST1, YSK3" ENSG00000101109 "Serine/threonine kinase 4" Q13043 20 44966474-45079959 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004038, HPA015270" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB004038: AB_2144632, HPA015270: AB_1854150" "unprognostic (2.77e-1)" "unprognostic (1.10e-1)" "unprognostic (8.83e-2)" "unprognostic (8.49e-3)" "unprognostic (2.95e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (8.04e-4)" "unprognostic (1.70e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.96e-1)" "unprognostic (2.70e-2)" "prognostic unfavourable (1.84e-5)" "unprognostic (1.28e-1)" "unprognostic (5.70e-2)" "unprognostic (3.96e-1)" "unprognostic (1.18e-2)" 9.5 8.8 10.4 24.5 11.5 39.5 8.1 7.5 13.4 7.8 8.6 10.3 5.4 8.1 9.3 6.5 8.9 7.3 9.4 6.1 9.3 8.8 6.3 7.4 18.8 30.6 10.5 9.1 8.3 6.4 5.9 9.3 8.2 7.7 7.5 10.6 7.4 9.3 8.7 4.2 11.4 16.1 8.2 12.0 29.1 9.6 7.4 9.6 32.3 8.0 4.9 36.6 11.5 8.7 10.8 6.9 40.6 13.3 10.3 14.5 7.9 11.6 7.9 10.1 7.2 6.2 7.8 7.0 10.3 15.8 17.5 15.9 22.4 6.4 28.6 9.0 7.3 12.4 10.7 13.8 22.5 12.8 5.7 20.8 11.6 15.7 10.9 26.7 29.6 6.3 11.4 16.4 17.9 6.4 9.6 16.5 8.8 9.2 19.9 18.1 6.2 5.4 12.9 11.2 13.3 6.4 8.0 4.8 5.9 15.3 8.9 11.7 8.1 16.9 8.2 13.2 12.9 15.2 11.9 21.6 16.9 31.8 12.9 12.8 9.7 24.4 7.6 20.5 14.5 7.7 14.4 10.3 13.8 13.3 6.9 10.8 14.3 11.9 40.6 10.3 13.3 3.9 13.3 7.9 10.4 11.5 7.5 13.4 9.3 8.8 10.5 9.1 7.7 9.6 STK40 "MGC4796, SgK495" ENSG00000196182 "Serine/threonine kinase 40" Q8N2I9 1 36339624-36385896 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 19.2" "Group enriched" "Detected in all" 5 "granulocytes: 19.2;monocytes: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008026 Uncertain Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA008026: AB_1857603" "unprognostic (3.32e-1)" "unprognostic (3.00e-1)" "unprognostic (6.47e-2)" "unprognostic (4.55e-1)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (2.69e-3)" "unprognostic (6.09e-2)" "unprognostic (2.09e-1)" "unprognostic (5.96e-2)" "prognostic favourable (5.59e-4)" "unprognostic (1.19e-1)" "unprognostic (2.75e-2)" "unprognostic (7.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" 22.9 7.2 9.8 15.3 9.4 9.2 26.5 8.9 11.1 10.2 19.1 7.4 16.7 9.4 11.8 12.2 22.3 11.3 18.2 25.6 10.0 7.1 14.3 23.5 16.6 15.4 13.1 7.4 22.2 34.4 9.2 14.7 19.2 12.1 15.7 9.1 9.0 25.1 17.7 53.9 17.2 10.8 26.0 10.3 17.2 17.0 32.0 8.9 9.2 14.6 20.7 16.6 19.5 26.6 2.4 2.7 19.2 8.5 1.6 2.9 2.4 7.0 3.1 15.6 16.2 11.1 6.4 8.8 7.2 9.8 8.7 9.4 17.1 10.2 30.0 5.9 6.7 7.1 14.2 3.1 6.4 13.0 11.1 19.6 2.9 21.8 11.0 11.4 26.2 5.8 11.8 6.7 3.5 5.4 24.0 10.9 5.4 11.1 11.8 15.1 10.0 4.3 13.6 10.6 19.9 5.4 8.0 19.1 9.7 5.5 8.7 23.9 5.9 13.5 9.0 5.5 11.5 16.1 15.8 11.4 6.4 25.3 28.6 10.0 18.0 1.0 3.0 4.9 2.6 6.7 2.9 2.3 1.7 1.7 2.7 2.4 1.0 1.5 19.2 1.6 8.5 2.6 1.0 2.4 9.8 9.4 8.9 11.1 10.0 7.1 13.1 7.4 12.1 8.9 STKLD1 "C9orf96, MGC43306, SGK071" ENSG00000198870 "Serine/threonine kinase like domain containing 1" Q8NE28 9 133376367-133406096 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 16.2" "Low cell line specificity" "Detected in some" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA029902 Uncertain "HPA029902: AB_10603554" "unprognostic (6.65e-2)" "unprognostic (9.43e-3)" "unprognostic (7.54e-4)" "unprognostic (8.15e-2)" "unprognostic (9.51e-2)" "unprognostic (1.39e-2)" "unprognostic (1.99e-2)" "unprognostic (1.41e-3)" "unprognostic (6.05e-2)" "unprognostic (2.94e-4)" "unprognostic (1.92e-4)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "unprognostic (4.69e-2)" "unprognostic (3.65e-1)" "unprognostic (5.86e-2)" "unprognostic (4.52e-2)" 0.4 0.4 0.4 0.2 1.4 0.5 0.4 0.7 2.2 0.4 0.3 2.2 1.3 0.5 0.9 2.1 0.3 0.6 0.5 0.3 0.8 0.3 0.3 0.4 0.3 0.8 0.5 1.3 0.8 0.4 0.1 0.3 0.5 1.5 0.5 0.1 0.8 0.6 0.4 0.6 0.8 0.5 0.3 0.5 0.4 0.4 16.2 0.7 0.0 0.3 0.0 0.3 0.3 0.3 0.6 0.4 0.0 0.2 0.2 0.6 0.0 0.0 0.6 0.4 0.6 0.5 0.5 1.1 0.2 0.0 0.1 0.2 0.9 0.3 0.3 0.2 0.0 0.6 0.1 0.0 0.0 0.4 0.8 0.7 0.9 0.5 0.3 0.5 0.4 0.4 0.1 0.0 0.1 0.0 0.8 1.0 0.0 0.2 0.6 0.8 0.3 1.0 0.3 0.3 0.8 0.1 0.1 1.0 1.0 0.3 0.9 2.1 1.3 0.2 0.6 1.0 0.6 0.9 0.1 2.2 2.1 0.6 0.4 0.4 0.3 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.4 0.2 0.1 0.6 0.6 0.2 0.0 0.2 0.1 0.4 0.0 0.0 0.4 1.4 0.7 2.2 0.8 0.3 0.5 1.3 1.5 0.7 STRADA "LYK5, NY-BR-96, Stlk, STRAD" ENSG00000266173 "STE20-related kinase adaptor alpha" Q7RTN6 17 63682336-63741986 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031637 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA031637: AB_10601718" "unprognostic (1.59e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-3)" "unprognostic (5.52e-2)" "unprognostic (8.91e-2)" "unprognostic (7.56e-5)" "unprognostic (6.79e-4)" "unprognostic (3.68e-2)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "prognostic favourable (5.34e-5)" "unprognostic (7.29e-2)" "prognostic unfavourable (6.08e-7)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "prognostic favourable (6.43e-4)" 13.3 17.7 19.4 14.6 23.7 17.5 13.0 25.0 28.4 15.2 13.2 27.1 8.7 9.5 16.1 20.6 14.3 20.9 14.5 15.1 18.9 20.2 14.7 13.0 13.9 19.6 20.9 21.7 18.5 12.5 21.9 17.5 14.4 26.0 13.8 13.1 22.2 12.6 16.7 10.3 20.1 12.0 19.1 19.4 20.7 12.6 55.4 21.4 16.2 13.3 8.9 21.3 12.9 12.8 11.2 16.2 18.6 10.0 15.6 11.7 7.5 7.2 21.7 18.9 19.0 18.6 13.9 7.4 13.8 12.7 19.9 17.8 5.6 8.4 11.0 8.6 11.7 6.0 12.5 13.3 19.8 12.2 12.1 21.8 15.2 13.4 13.2 20.6 15.7 14.5 11.5 22.6 13.0 22.0 13.9 11.8 18.8 13.4 24.2 14.1 9.4 12.3 15.8 30.1 13.5 17.8 14.3 20.7 23.2 9.4 15.5 15.1 11.4 15.0 17.6 19.0 13.5 15.3 11.4 11.8 12.5 13.9 14.1 12.5 14.9 18.6 9.5 8.6 10.5 7.1 9.7 11.2 9.7 11.7 16.2 9.0 9.6 8.5 11.4 15.6 10.0 13.7 7.2 7.5 19.4 23.7 25.0 28.4 18.9 20.2 20.9 21.7 26.0 21.4 STRADB "ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK" ENSG00000082146 "STE20-related kinase adaptor beta" Q9C0K7 2 201387858-201480846 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 59.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026549, HPA028520" Approved Supported Aggresome,Cytosol Cytosol Aggresome "HPA026549: AB_1844779, HPA028520: AB_10604100" "unprognostic (6.34e-2)" "unprognostic (2.48e-1)" "unprognostic (2.63e-1)" "unprognostic (3.56e-3)" "unprognostic (4.04e-2)" "unprognostic (7.64e-2)" "unprognostic (1.35e-1)" "unprognostic (1.58e-1)" "unprognostic (2.63e-3)" "unprognostic (2.65e-2)" "unprognostic (6.21e-2)" "unprognostic (2.74e-2)" "prognostic unfavourable (1.35e-4)" "unprognostic (1.08e-1)" "unprognostic (7.83e-2)" "prognostic favourable (4.45e-4)" "unprognostic (4.93e-2)" 13.8 28.6 13.8 7.9 11.7 32.7 9.2 8.8 13.5 6.4 13.7 16.9 4.9 18.8 10.3 9.5 8.9 5.7 7.9 15.2 15.3 11.5 35.2 50.5 7.2 10.1 15.8 11.0 7.8 9.1 3.9 14.1 11.6 12.7 7.1 15.9 10.1 7.1 7.7 48.3 4.4 21.3 7.4 21.0 7.3 4.7 7.8 9.4 8.3 9.7 7.8 7.7 6.2 6.2 24.1 10.4 9.7 8.6 16.3 10.4 9.6 3.9 6.8 11.8 15.1 19.3 24.5 8.3 8.0 13.9 11.1 16.8 8.9 3.8 0.0 5.2 12.6 4.0 11.4 7.5 20.2 4.6 9.3 4.7 3.2 19.7 14.6 5.6 5.4 20.7 6.9 14.2 12.8 8.3 10.1 1.7 59.9 2.1 5.1 9.8 15.9 7.0 7.0 4.6 2.9 9.4 3.2 1.9 9.7 5.5 4.2 23.4 2.2 10.7 8.0 6.8 5.2 8.6 6.1 6.6 11.7 1.8 11.5 2.5 6.4 3.4 8.0 9.7 6.0 8.6 5.4 16.7 8.0 8.6 10.4 24.1 10.4 10.3 1.6 16.3 7.5 4.6 9.5 9.6 13.8 11.7 8.8 13.5 15.3 11.5 15.8 11.0 12.7 9.4 STS "ARSC, ARSC1" ENSG00000101846 "Steroid sulfatase" P08842 X 7219456-7354810 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Pregnancy, Steroid metabolism" Hydrolase "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "placenta: 258.8" "Cell line enhanced" "Detected in many" "ASC diff: 19.9;RPMI-8226: 25.4;U-266/70: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 4.7" "Low lineage specificity" "Detected in many" HPA002904 Enhanced "HPA002904: AB_1080116" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (2.75e-1)" "unprognostic (6.72e-2)" "unprognostic (1.94e-2)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (8.23e-2)" "unprognostic (4.67e-2)" "prognostic unfavourable (3.47e-4)" "unprognostic (4.05e-2)" "unprognostic (2.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" 10.3 2.2 3.0 2.2 3.9 0.0 4.1 2.3 9.0 3.4 3.5 2.3 2.2 0.8 2.4 2.2 2.2 2.6 4.1 3.6 3.9 4.0 2.5 4.7 5.0 2.2 3.8 2.4 2.4 2.2 1.6 2.2 258.8 2.4 2.9 3.0 2.3 2.2 3.3 4.0 2.3 2.4 3.8 2.4 2.2 6.7 2.2 2.3 2.2 2.4 2.2 2.2 4.9 2.7 0.9 1.9 1.9 4.7 1.0 0.7 1.0 4.0 1.2 2.7 0.9 19.9 10.3 14.7 8.3 3.0 2.2 2.1 7.2 3.8 7.6 1.6 6.0 1.0 1.6 1.3 2.2 0.6 3.2 0.4 4.6 2.0 1.1 1.1 4.3 3.4 0.2 1.4 0.8 3.4 0.4 7.9 5.9 0.9 0.6 1.0 1.0 1.8 1.0 1.6 25.4 5.6 5.9 2.0 1.7 1.6 3.0 0.9 1.2 0.4 5.9 8.9 0.5 11.4 1.3 42.2 0.0 17.7 2.1 0.9 2.3 0.0 3.2 0.6 0.5 4.7 0.2 0.6 0.2 0.3 1.9 0.9 0.1 0.5 1.9 1.0 2.5 0.3 0.7 1.0 3.0 3.9 2.3 9.0 3.9 4.0 3.8 2.4 2.4 2.3 STT3A "ITM1, MGC9042, STT3-A, TMC" ENSG00000134910 "STT3A, catalytic subunit of the oligosaccharyltransferase complex" P46977 11 125591712-125625215 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 202.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030735 Approved Uncertain Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Cytosol" Vesicles "HPA030735: AB_10603342" "unprognostic (8.25e-3)" "unprognostic (5.45e-2)" "unprognostic (3.02e-2)" "prognostic favourable (1.32e-4)" "unprognostic (5.10e-2)" "unprognostic (1.72e-2)" "prognostic unfavourable (3.57e-4)" "unprognostic (8.40e-2)" "unprognostic (4.80e-2)" "unprognostic (1.16e-2)" "unprognostic (8.96e-3)" "unprognostic (1.31e-1)" "prognostic unfavourable (4.96e-4)" "unprognostic (2.60e-2)" "unprognostic (6.38e-2)" "unprognostic (1.28e-1)" "unprognostic (1.82e-2)" 20.6 20.5 8.3 13.1 11.7 8.3 16.9 10.7 13.9 27.8 19.3 17.7 39.6 12.0 30.5 41.4 19.6 20.8 15.1 19.5 8.3 9.1 26.2 67.1 18.7 14.9 9.3 7.7 30.1 59.0 202.3 27.5 35.9 11.6 22.2 17.4 20.8 50.7 41.4 9.5 12.9 19.8 17.1 12.3 21.8 17.7 17.1 6.7 19.2 38.6 13.6 20.8 19.5 18.0 15.0 53.2 27.0 15.5 17.2 27.5 13.4 20.7 18.9 24.2 33.2 45.6 35.4 26.0 38.0 45.4 31.0 38.8 57.5 56.2 27.1 46.2 55.9 38.4 33.5 33.3 41.2 21.1 17.8 63.8 13.1 39.7 50.5 38.1 29.9 27.3 24.2 42.8 83.7 34.5 26.8 40.6 39.0 15.3 15.3 12.2 15.5 20.6 18.2 20.6 40.7 33.8 32.3 15.1 13.0 26.9 44.0 13.5 51.5 27.5 30.8 44.6 16.1 18.8 29.8 12.8 14.9 20.9 17.2 38.6 35.4 27.0 15.5 11.6 19.7 14.8 27.5 15.0 19.1 18.2 21.6 11.6 13.8 16.0 5.4 17.2 13.0 53.2 14.1 13.4 8.3 11.7 10.7 13.9 8.3 9.1 9.3 7.7 11.6 6.7 STT3B "FLJ90106, SIMP, STT3-B" ENSG00000163527 "STT3B, catalytic subunit of the oligosaccharyltransferase complex" Q8TCJ2 3 31532638-31637622 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036448, HPA036646" Approved Supported "Endoplasmic reticulum" 9300 "Endoplasmic reticulum" "HPA036448: , HPA036646: AB_10673472" "unprognostic (2.17e-2)" "unprognostic (2.23e-1)" "prognostic favourable (7.91e-5)" "unprognostic (1.60e-1)" "unprognostic (3.11e-1)" "unprognostic (2.74e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-1)" "unprognostic (1.04e-1)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (3.68e-2)" "unprognostic (3.86e-2)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (6.71e-3)" "unprognostic (1.02e-1)" 23.0 30.3 16.0 27.5 16.7 21.7 27.4 15.4 19.4 28.4 25.0 16.9 37.0 18.6 28.4 37.9 28.8 22.4 29.0 27.5 15.1 15.6 28.2 64.1 30.1 36.9 16.5 15.5 62.3 39.4 36.2 20.3 85.9 16.5 26.3 25.1 22.3 25.2 26.3 31.2 19.2 29.2 23.2 19.7 29.4 22.9 36.7 13.6 60.2 44.3 23.4 30.3 27.5 27.7 3.6 7.7 8.4 5.3 8.4 8.5 3.0 16.3 27.5 25.3 26.5 31.9 32.3 55.4 30.7 27.0 23.0 26.7 25.0 35.6 28.5 15.1 27.8 13.9 23.4 26.6 30.2 80.2 15.4 24.4 28.0 26.6 24.6 52.5 29.1 24.7 28.6 32.7 41.4 23.2 13.1 45.7 31.3 9.2 51.4 32.5 20.4 15.5 53.8 13.7 41.3 26.8 23.7 10.8 13.2 30.4 45.2 17.8 20.4 28.1 45.1 31.1 19.9 30.7 27.0 28.8 34.5 23.9 28.2 36.2 25.5 2.3 4.6 8.4 4.7 5.3 7.5 3.4 8.5 6.5 4.0 3.6 8.2 6.5 1.7 8.4 3.7 7.7 4.1 3.0 16.0 16.7 15.4 19.4 15.1 15.6 16.5 15.5 16.5 13.6 STUB1 "CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1" ENSG00000103266 "STIP1 homology and U-box containing protein 1" Q9UNE7 16 680224-682870 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037202, CAB037209, HPA041222, HPA043531" Enhanced Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB037202: AB_1840759, CAB037209: AB_1840757, HPA041222: AB_2677368, HPA043531: AB_2678533" "unprognostic (5.70e-2)" "unprognostic (2.53e-1)" "unprognostic (1.90e-1)" "unprognostic (3.89e-1)" "unprognostic (9.00e-2)" "unprognostic (3.06e-1)" "unprognostic (4.09e-3)" "unprognostic (2.21e-1)" "unprognostic (2.23e-1)" "unprognostic (8.31e-2)" "unprognostic (5.78e-2)" "unprognostic (6.77e-2)" "prognostic favourable (6.49e-9)" "unprognostic (9.67e-2)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.30e-1)" 29.4 43.7 52.2 20.1 43.2 19.3 40.5 39.1 53.3 25.1 24.8 18.1 27.6 24.1 19.7 34.9 35.2 31.1 25.5 45.2 43.2 38.6 24.0 25.9 23.6 28.1 42.0 42.5 29.4 43.4 39.8 27.2 12.1 35.0 23.4 17.7 18.6 37.7 29.7 92.5 33.7 20.9 24.5 34.5 19.7 22.8 13.8 25.4 13.1 29.1 30.2 19.4 22.3 35.9 18.0 21.0 19.4 14.5 10.3 16.9 6.9 17.8 24.2 16.4 27.7 37.5 34.4 9.4 24.4 28.7 29.0 25.8 30.1 22.8 18.1 17.3 40.8 15.3 20.2 36.7 12.1 19.9 66.8 11.2 35.0 25.1 54.1 18.9 22.4 40.8 39.4 33.9 21.5 29.3 18.1 30.3 44.8 70.7 20.5 18.6 18.3 26.5 31.7 10.7 44.5 38.7 17.9 28.6 23.2 19.5 43.0 30.6 27.4 36.3 23.2 26.6 23.3 22.0 29.3 30.0 31.0 29.2 21.0 17.2 30.0 11.9 14.5 19.4 16.9 11.9 15.4 18.0 14.6 14.7 11.7 17.3 13.6 12.9 14.0 10.3 12.4 21.0 12.2 6.9 52.2 43.2 39.1 53.3 43.2 38.6 42.0 42.5 35.0 25.4 STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618939-10674318 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.8;stomach 1: 16.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.2;HDLM-2: 10.8;HMC-1: 11.9;HUVEC TERT2: 16.4;TIME: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA040468: , HPA048569: " "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" 0.6 0.3 2.6 2.3 10.6 1.0 3.8 0.1 13.4 2.2 14.4 0.7 0.5 2.1 0.5 1.1 8.9 1.9 6.2 0.1 1.8 1.6 0.5 0.3 1.2 2.4 1.8 4.2 0.4 0.3 0.0 8.4 3.4 2.1 10.6 15.8 0.0 7.8 2.6 0.2 2.6 10.3 0.6 0.6 1.0 16.0 0.3 0.7 0.0 0.4 0.6 2.8 4.3 3.6 0.0 0.0 0.4 0.0 12.5 1.9 0.2 2.9 0.1 0.0 0.4 0.0 0.0 0.9 4.8 0.5 2.2 2.1 1.6 18.2 0.2 3.1 1.2 0.8 0.9 5.0 4.8 10.8 0.3 0.7 1.3 0.1 0.0 1.4 11.9 0.2 0.2 3.4 0.2 16.4 0.2 0.2 5.2 1.7 0.1 0.8 2.7 1.3 0.0 1.4 0.2 1.6 9.4 0.6 0.0 2.7 2.9 0.0 2.3 0.3 15.2 0.6 2.5 0.3 0.6 0.0 0.6 0.1 2.1 0.1 3.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.3 0.4 12.5 0.0 0.0 0.0 0.2 2.6 10.6 0.1 13.4 1.8 1.6 1.8 4.2 2.1 0.7 SUCLA2 ENSG00000136143 "Succinate-CoA ligase ADP-forming beta subunit" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria 6600 Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favourable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavourable (1.22e-4)" 21.6 18.5 19.2 8.6 22.1 5.2 17.5 29.7 32.4 15.3 15.7 11.7 15.6 24.5 12.7 12.1 14.6 11.3 9.4 42.1 20.0 21.6 34.0 12.9 7.9 11.4 22.6 19.1 14.4 10.8 19.8 14.9 12.2 28.7 16.2 16.5 8.9 13.9 14.8 89.0 10.0 22.7 14.7 18.3 9.7 12.3 8.0 15.4 15.6 16.9 25.6 10.2 11.0 12.6 17.1 29.5 12.4 25.0 23.4 25.2 17.2 17.2 20.0 25.4 15.2 29.1 22.0 15.3 26.4 29.6 27.5 18.7 35.5 19.6 24.2 20.2 25.8 24.0 33.5 25.1 34.9 23.1 28.7 27.2 19.0 23.0 20.3 27.5 15.9 20.7 29.6 18.7 22.1 20.2 18.3 8.8 27.3 11.9 28.3 31.5 26.3 25.6 24.1 23.2 18.7 39.7 16.7 14.1 16.8 22.0 20.4 15.5 18.1 24.4 15.4 15.3 9.9 21.7 18.3 9.1 14.2 28.2 9.5 20.1 22.4 5.7 24.5 12.4 17.6 25.0 21.2 17.1 19.7 21.6 29.5 16.3 25.2 24.9 4.5 23.4 20.0 24.3 21.6 17.2 19.2 22.1 29.7 32.4 20.0 21.6 22.6 19.1 28.7 15.4 SUCLG1 ENSG00000163541 "Succinate-CoA ligase alpha subunit" P53597 2 84423523-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 125.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Supported "Plasma membrane,Mitochondria" "Intracellular and membrane" 330000 Mitochondria "Plasma membrane" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavourable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favourable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 26.1 23.3 18.0 15.0 18.9 10.6 23.8 18.9 19.5 14.1 50.1 17.7 23.2 53.9 13.9 19.6 25.0 13.5 14.0 57.7 17.4 17.3 125.6 44.1 12.8 13.3 19.2 17.0 12.7 33.9 36.2 16.3 13.8 17.3 17.1 39.4 16.9 39.3 24.9 57.6 15.6 71.6 26.5 17.1 12.1 21.9 13.3 16.0 16.9 28.8 42.8 15.2 24.3 16.3 26.6 43.5 31.6 40.3 35.2 39.1 46.8 23.5 25.9 20.5 25.0 38.6 26.0 35.5 26.9 23.0 34.6 25.3 59.3 19.5 32.4 18.6 32.1 34.4 42.1 31.6 41.2 31.3 38.3 28.1 22.4 33.7 32.6 28.6 23.0 30.9 26.0 29.1 39.8 30.8 28.5 26.7 31.5 36.0 40.6 26.2 10.7 46.4 25.8 47.5 35.5 46.4 28.6 24.9 13.9 21.4 44.5 42.7 27.1 22.6 24.8 27.2 26.3 33.3 32.9 23.5 33.3 28.0 31.7 39.7 23.9 31.6 34.4 28.7 31.4 40.3 34.6 26.6 29.2 35.1 43.5 20.2 32.4 34.2 18.5 35.2 40.0 23.7 39.1 46.8 18.0 18.9 18.9 19.5 17.4 17.3 19.2 17.0 17.3 16.0 SUCLG2 ENSG00000172340 "Succinate-CoA ligase GDP-forming beta subunit" Q96I99 3 67360460-67654614 "Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 90.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046705, HPA051998" Enhanced Supported "Plasma membrane,Mitochondria" 290000 "Plasma membrane, Mitochondria" "HPA046705: AB_2679762, HPA051998: AB_2681687" "unprognostic (1.69e-1)" "unprognostic (2.31e-1)" "prognostic favourable (1.08e-4)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (5.32e-2)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (3.88e-1)" "unprognostic (3.26e-2)" "unprognostic (4.61e-3)" "unprognostic (5.59e-2)" "prognostic favourable (2.79e-10)" "unprognostic (3.08e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" 17.0 19.3 8.8 26.5 10.0 3.4 12.4 2.4 7.2 15.3 38.9 9.5 16.4 31.4 11.5 18.3 18.6 9.9 27.9 23.6 6.6 6.2 38.3 90.9 14.6 21.1 9.8 6.5 16.5 20.9 5.9 8.5 8.5 7.6 14.0 34.5 9.6 21.0 17.3 57.0 9.3 42.4 23.5 8.6 24.7 25.4 6.5 8.1 9.6 16.4 27.0 16.7 19.9 13.2 19.2 10.2 5.8 18.2 27.1 31.1 18.9 13.8 12.1 12.0 14.6 20.2 35.1 14.7 16.6 24.4 19.6 21.9 13.4 31.0 17.7 5.4 23.4 7.1 9.3 23.0 25.5 7.5 6.4 16.1 11.0 20.8 26.1 21.1 11.3 26.2 20.0 15.3 35.3 20.8 12.2 16.3 42.6 9.7 7.9 6.7 11.2 7.5 5.5 18.6 26.5 33.2 21.6 2.3 8.2 26.4 30.6 22.0 23.5 13.6 18.1 19.5 12.8 21.4 19.7 11.1 16.2 12.5 28.6 16.5 22.9 5.8 15.3 5.2 13.8 18.2 16.7 19.2 20.0 17.4 10.2 16.7 31.1 23.7 0.7 27.1 14.8 4.0 18.5 18.9 8.8 10.0 2.4 7.2 6.6 6.2 9.8 6.5 7.6 8.1 SUGCT "C7orf10, DERP13, FLJ11808, ORF19" ENSG00000175600 "Succinyl-CoA:glutarate-CoA transferase" Q9HAC7 7 40134977-40860763 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.1;liver: 27.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 27.5;LHCN-M2: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 4.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026698, HPA026704, HPA026705" Enhanced "HPA026698: AB_10600191, HPA026704: AB_10600230, HPA026705: AB_10601003" "unprognostic (4.66e-3)" "unprognostic (3.45e-2)" "unprognostic (2.06e-2)" "unprognostic (3.32e-3)" "unprognostic (5.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.14e-3)" "unprognostic (1.75e-2)" "unprognostic (2.61e-1)" "unprognostic (1.80e-1)" "unprognostic (5.27e-3)" "unprognostic (7.65e-2)" "prognostic favourable (3.93e-7)" "unprognostic (2.62e-2)" "unprognostic (3.38e-1)" "unprognostic (3.41e-3)" "prognostic unfavourable (2.53e-4)" 2.7 13.5 3.2 5.1 4.6 0.7 4.0 1.1 3.1 4.4 5.0 1.1 0.7 1.4 9.6 2.9 3.2 2.7 4.5 6.9 4.3 2.4 42.1 27.6 1.2 3.9 2.8 2.4 5.7 3.8 3.8 3.5 1.2 4.8 3.4 2.9 5.4 2.4 4.3 11.3 1.6 5.6 13.9 5.0 1.3 1.8 4.1 4.1 0.0 2.4 6.3 1.5 2.9 3.5 1.4 0.2 1.1 0.2 0.0 4.6 0.7 0.5 0.0 3.0 2.3 3.3 7.6 1.2 1.5 2.9 2.2 2.5 1.2 0.6 2.0 0.7 2.2 0.1 1.0 27.5 3.4 0.0 1.3 1.7 0.2 4.4 4.1 0.2 0.2 9.6 6.2 2.3 1.4 0.6 2.3 0.3 16.5 0.0 0.1 0.3 5.2 2.3 1.9 0.3 0.0 4.7 0.0 0.2 1.7 2.5 1.1 3.5 0.1 0.4 2.3 9.4 2.7 0.1 0.6 0.2 0.0 0.1 1.8 0.8 2.1 0.0 0.1 0.3 0.7 0.0 1.2 1.4 2.0 1.0 0.1 1.2 4.6 2.7 1.1 0.0 0.2 0.2 0.0 0.7 3.2 4.6 1.1 3.1 4.3 2.4 2.8 2.4 4.8 4.1 SULT1A1 "P-PST, STP, STP1" ENSG00000196502 "Sulfotransferase family 1A member 1" P50225 16 28605196-28623625 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 98.1" "Group enriched" "Detected in many" 4 "EFO-21: 41.4;Hep G2: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 50.6;intermediate monocyte: 39.2;myeloid DC: 22.9;neutrophil: 47.7;non-classical monocyte: 22.3" "Group enriched" "Detected in many" 26 "dendritic cells: 22.9;granulocytes: 47.7;monocytes: 50.6" "HPA049500, HPA051051" Supported 3700000 "HPA049500: , HPA051051: " "unprognostic (2.57e-2)" "unprognostic (2.80e-2)" "unprognostic (8.40e-2)" "unprognostic (1.30e-1)" "unprognostic (5.60e-3)" "unprognostic (7.63e-2)" "unprognostic (4.17e-2)" "prognostic favourable (7.02e-4)" "unprognostic (1.30e-1)" "unprognostic (2.40e-1)" "unprognostic (6.71e-2)" "unprognostic (2.07e-1)" "unprognostic (3.70e-3)" "unprognostic (1.49e-1)" "unprognostic (4.10e-2)" "unprognostic (7.39e-2)" "unprognostic (1.89e-2)" 10.2 36.1 12.0 7.2 15.4 9.3 5.7 15.8 19.8 4.6 21.4 4.5 15.5 54.2 3.7 14.4 3.1 6.6 5.4 9.7 14.7 10.4 11.0 98.1 26.7 8.4 9.2 14.9 3.5 9.6 6.7 10.0 5.6 10.3 3.7 17.5 12.2 11.5 22.5 4.9 1.4 41.1 5.2 6.3 23.2 7.2 5.1 4.6 4.0 13.4 2.6 3.7 6.3 2.2 0.3 22.9 47.7 50.6 0.9 1.5 19.3 1.5 0.6 0.8 2.7 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.3 10.3 0.2 41.4 0.0 0.6 0.8 2.8 0.0 0.3 7.3 2.8 3.1 82.0 4.9 0.0 3.2 0.2 0.2 0.0 0.0 0.7 1.1 1.3 0.8 9.7 0.2 2.2 0.7 0.0 3.0 0.3 5.4 0.7 0.8 2.5 0.2 0.7 13.4 0.3 8.0 7.9 5.4 0.2 2.0 0.2 0.1 3.2 1.9 0.4 0.7 15.1 0.0 4.9 50.6 0.9 0.6 39.2 0.7 0.3 0.6 0.5 22.9 0.1 0.9 0.6 47.7 0.9 22.3 1.7 1.5 19.3 12.0 15.4 15.8 19.8 14.7 10.4 9.2 14.9 10.3 4.6 SULT1A2 "HAST4, STP2" ENSG00000197165 "Sulfotransferase family 1A member 2" P50226 16 28591943-28597109 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.5;liver: 26.2;seminal vesicle: 24.2" "Cell line enhanced" "Detected in many" "BEWO: 6.7;EFO-21: 8.6;Hep G2: 31.9" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 7 "classical monocyte: 10.2;intermediate monocyte: 7.0;myeloid DC: 3.5;neutrophil: 12.6;non-classical monocyte: 3.6" "Group enriched" "Detected in many" 16 "dendritic cells: 3.5;granulocytes: 12.6;monocytes: 10.2" "HPA049500, HPA051051" Supported "HPA049500: , HPA051051: " "unprognostic (4.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.53e-1)" "unprognostic (6.13e-2)" "unprognostic (5.35e-2)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "unprognostic (1.05e-1)" "unprognostic (2.49e-4)" "unprognostic (5.83e-2)" "unprognostic (2.81e-1)" "unprognostic (1.02e-1)" "unprognostic (2.74e-1)" "unprognostic (2.98e-1)" "unprognostic (1.44e-1)" "unprognostic (8.52e-3)" 1.0 1.9 0.6 2.5 1.0 0.5 1.2 1.6 0.7 0.3 9.8 0.6 5.9 25.7 0.5 1.1 0.9 0.6 1.6 2.1 0.8 0.5 2.3 26.2 11.9 0.3 0.6 0.6 0.9 1.4 1.0 1.2 2.7 0.7 0.3 6.8 4.6 0.9 24.2 0.2 0.2 37.5 0.2 0.6 2.7 0.7 0.3 0.2 0.5 4.5 0.5 0.2 1.9 1.1 0.2 3.5 12.6 10.2 0.4 0.5 3.9 1.3 0.6 0.6 0.5 0.1 0.3 6.7 0.7 0.0 0.1 0.0 1.3 2.9 0.2 8.6 0.2 1.1 0.3 0.4 0.2 0.4 0.3 1.2 1.6 31.9 0.5 1.0 1.3 0.2 0.5 0.5 0.1 0.2 0.7 1.4 0.1 1.5 0.2 2.0 1.0 0.3 1.2 0.2 0.6 0.1 1.3 0.4 0.9 0.2 4.5 0.0 3.1 0.6 0.4 1.6 1.0 1.3 0.5 2.4 1.3 0.3 0.4 0.5 0.5 1.1 10.2 0.1 0.3 7.0 0.5 0.1 0.2 0.2 3.5 0.2 0.3 0.3 12.6 0.4 3.6 0.8 0.4 3.9 0.6 1.0 1.6 0.7 0.8 0.5 0.6 0.6 0.7 0.2 SULT1A3 "STM, TL-PST" ENSG00000261052 "Sulfotransferase family 1A member 3" P0DMM9 16 30199228-30204310 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 27.8;intestine: 31.0" "Cell line enhanced" "Detected in all" "CAPAN-2: 39.2;Hep G2: 53.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "classical monocyte: 27.8;intermediate monocyte: 24.0;myeloid DC: 16.2;non-classical monocyte: 11.1" "Group enriched" "Detected in many" 11 "dendritic cells: 16.2;monocytes: 27.8" "HPA049500, HPA051051" Supported 3200000 "HPA049500: , HPA051051: " "unprognostic (2.61e-1)" "unprognostic (1.72e-3)" "unprognostic (1.98e-3)" "unprognostic (4.98e-2)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (7.27e-2)" "unprognostic (2.09e-2)" "unprognostic (2.99e-2)" "unprognostic (2.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.18e-8)" "unprognostic (2.34e-2)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (9.48e-5)" 1.4 3.8 5.6 4.3 4.9 7.5 2.5 14.0 6.3 2.1 6.7 31.0 2.5 4.5 4.0 3.7 2.0 1.7 5.6 5.2 6.6 10.1 3.8 3.2 4.3 2.9 4.3 8.1 8.0 3.0 5.8 6.1 5.3 5.2 1.5 5.6 17.9 4.0 3.4 5.7 2.7 2.1 6.4 5.8 3.6 2.4 1.5 16.2 1.4 27.8 0.4 2.0 11.2 4.8 10.1 10.0 7.0 9.2 5.3 13.5 5.4 4.5 5.4 6.1 4.3 39.2 4.9 28.4 5.1 12.7 10.4 4.2 5.3 4.5 7.5 3.9 13.8 53.7 3.8 3.3 9.2 7.4 6.8 5.9 2.1 6.2 1.2 31.0 3.7 14.9 2.6 20.5 5.9 5.9 10.9 4.0 9.0 7.0 4.4 4.0 5.2 1.4 15.9 2.3 6.0 7.3 2.3 10.6 5.2 7.8 3.1 9.2 8.6 3.0 3.8 5.7 6.3 1.4 27.8 0.1 2.0 24.0 0.3 1.5 0.3 0.6 16.2 0.3 0.3 0.3 0.4 0.4 11.1 0.2 0.3 11.2 SULT1A4 ENSG00000213648 "Sulfotransferase family 1A member 4" P0DMN0 16 29459889-29464976 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 16.7;intestine: 38.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 30.9;EFO-21: 25.6;HEL: 20.9;Hep G2: 67.7;Karpas-707: 40.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "classical monocyte: 11.3;intermediate monocyte: 16.7;myeloid DC: 11.3;non-classical monocyte: 5.0" "Group enriched" "Detected in many" 16 "dendritic cells: 11.3;monocytes: 16.7" "HPA049500, HPA051051" Supported "HPA049500: , HPA051051: " "unprognostic (4.14e-2)" "unprognostic (1.04e-1)" 2.7 0.7 3.3 2.0 1.6 0.9 2.0 4.3 2.6 3.0 8.1 38.8 1.2 0.0 0.3 1.7 1.6 1.7 2.8 1.6 2.8 1.7 3.4 2.9 1.5 0.9 0.6 0.0 1.8 2.4 2.2 7.6 1.8 0.0 0.7 5.2 25.9 2.7 1.1 3.3 3.2 1.1 3.4 2.1 0.1 1.0 0.6 11.3 0.8 16.7 0.2 0.6 2.4 4.0 4.0 1.2 0.1 0.1 1.4 1.7 0.4 0.7 0.1 0.1 2.3 30.9 0.2 25.6 0.2 4.4 1.7 0.4 0.1 1.5 2.3 20.9 2.7 67.7 0.6 0.7 2.9 0.0 0.0 2.0 0.0 4.8 4.2 40.4 0.1 2.0 0.4 3.1 0.9 0.7 1.7 0.6 1.1 2.9 2.8 0.9 2.2 0.0 6.2 0.0 1.3 0.0 8.4 0.8 0.4 1.2 0.7 1.7 13.7 0.4 1.9 3.7 0.2 0.2 11.3 0.0 0.6 16.7 0.1 0.6 0.3 0.1 11.3 0.5 0.3 0.1 0.8 0.2 5.0 0.2 0.3 2.4 SULT1E1 "EST, STE" ENSG00000109193 "Sulfotransferase family 1E member 1" P49888 4 69841212-69860152 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.8;liver: 26.2;vagina: 15.8" "Group enriched" "Detected in some" 19 "HHSteC: 37.1;HSkMC: 16.8;hTCEpi: 14.0;HUVEC TERT2: 10.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 8 "pons and medulla: 3.3" "Cell type enhanced" "Detected in single" "neutrophil: 1.7" "Low lineage specificity" "Detected in single" "HPA028213, HPA028728, CAB047344" Enhanced Uncertain "Nuclear membrane,Cytosol" "Nuclear membrane, Cytosol" "CAB047344: , HPA028213: AB_10599848, HPA028728: AB_10601894" "unprognostic (5.60e-2)" "prognostic favourable (4.06e-4)" "unprognostic (2.48e-1)" "unprognostic (1.07e-3)" "unprognostic (2.42e-1)" "unprognostic (1.95e-1)" "unprognostic (1.70e-1)" "unprognostic (1.72e-1)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (3.22e-3)" "unprognostic (8.62e-2)" "unprognostic (6.48e-5)" "unprognostic (2.48e-1)" "unprognostic (4.11e-2)" "unprognostic (5.55e-2)" 0.1 9.8 0.1 0.1 0.3 0.1 1.1 0.1 0.4 13.1 8.9 0.5 0.1 19.8 0.4 3.7 0.4 0.1 1.2 0.1 0.1 0.0 1.5 26.2 2.0 0.1 0.3 0.3 0.2 0.1 0.0 0.4 0.1 3.3 1.0 0.1 0.3 4.7 0.3 0.1 10.9 37.8 0.5 0.3 0.1 1.3 0.4 0.1 0.6 0.2 0.1 1.0 0.4 15.8 0.6 0.2 1.7 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 37.1 0.0 0.0 16.8 14.0 0.0 0.4 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.1 0.6 0.2 0.1 1.7 0.3 0.3 0.2 0.0 0.0 0.1 0.3 0.1 0.4 0.1 0.0 0.3 0.3 3.3 0.1 SULT2A1 "DHEA-ST, STD" ENSG00000105398 "Sulfotransferase family 2A member 1" Q06520 19 47870466-47886397 "Enzymes, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 211.7" "Group enriched" "Detected in some" 34 "Hep G2: 26.0;RT4: 17.7" "Cancer enriched" "Detected in some" 52 "liver cancer: 244.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "basophil: 5.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB018755, HPA041487, HPA063633" Enhanced Supported Cytosol 210000 Cytosol "CAB018755: AB_650242, HPA041487: AB_2677507, HPA063633: AB_2685066" "unprognostic (2.14e-1)" "unprognostic (6.79e-3)" "unprognostic (6.82e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-2)" 0.1 46.9 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 11.4 1.1 1.1 8.2 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.1 211.7 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.1 0.1 0.2 0.6 0.0 0.1 0.1 3.9 0.1 0.0 42.7 0.1 0.1 0.1 2.8 0.7 0.1 0.1 0.2 0.1 0.1 0.6 0.2 1.3 1.0 5.3 0.8 2.3 1.3 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 26.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.3 0.2 0.0 17.7 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 5.3 0.8 0.7 0.9 0.4 0.6 0.7 1.0 0.6 0.3 1.3 1.3 1.0 3.1 2.3 0.4 1.0 0.6 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 SULT2B1 HSST2 ENSG00000088002 "Sulfotransferase family 2B member 1" O00204 19 48552075-48599425 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 91.8;lymphoid tissue: 78.6;tongue: 79.6" "Cell line enhanced" "Detected in some" "A549: 7.1;CAPAN-2: 34.1;MCF7: 20.9;T-47d: 17.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB033013, HPA041724, HPA043539" Approved Supported Vesicles,Cytosol "Vesicles, Cytosol" "CAB033013: AB_661450, HPA041724: AB_2677638, HPA043539: AB_2678540" "unprognostic (6.55e-2)" "unprognostic (1.47e-1)" "unprognostic (5.28e-3)" "unprognostic (8.74e-2)" "unprognostic (5.00e-2)" "unprognostic (5.97e-2)" "unprognostic (4.43e-2)" "unprognostic (3.29e-3)" "unprognostic (1.62e-1)" "unprognostic (1.11e-2)" "unprognostic (2.54e-2)" "unprognostic (4.42e-2)" "unprognostic (5.01e-6)" "unprognostic (7.96e-3)" "unprognostic (1.32e-1)" "unprognostic (8.04e-2)" "unprognostic (2.77e-2)" 0.1 0.1 0.1 0.3 0.1 0.0 4.0 0.1 0.2 28.7 0.8 0.0 9.2 2.9 2.2 5.2 91.8 0.3 2.3 0.0 0.1 0.1 2.5 0.1 6.5 0.0 0.2 0.0 0.1 0.2 0.8 0.1 11.4 0.0 6.9 0.0 0.0 12.4 6.9 0.2 45.7 13.4 0.0 0.1 0.0 0.7 0.2 0.0 0.5 1.1 79.6 78.6 0.6 32.0 0.7 1.5 2.5 1.0 1.1 3.1 0.9 5.6 7.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 34.1 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.2 0.0 0.2 0.2 0.0 0.0 3.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 20.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 2.9 0.1 17.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.5 0.8 0.4 2.1 0.9 3.1 0.4 1.8 1.4 0.7 0.7 0.6 1.2 1.4 1.1 1.0 1.5 1.1 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 SUOX ENSG00000139531 "Sulfite oxidase" P51687 12 55997180-56006641 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038208, HPA038209" Approved 26000 "HPA038208: AB_2675892, HPA038209: AB_10672738" "unprognostic (1.72e-1)" "unprognostic (7.40e-2)" "unprognostic (2.04e-1)" "unprognostic (1.25e-2)" "unprognostic (1.86e-1)" "unprognostic (9.72e-3)" "unprognostic (1.71e-3)" "unprognostic (2.86e-3)" "unprognostic (3.27e-2)" "unprognostic (9.74e-2)" "prognostic favourable (6.28e-4)" "unprognostic (6.95e-2)" "prognostic favourable (4.77e-7)" "unprognostic (1.65e-1)" "unprognostic (1.89e-1)" "unprognostic (2.85e-2)" "prognostic favourable (8.32e-5)" 12.2 25.4 11.9 6.4 13.3 7.5 11.9 9.7 21.3 12.4 11.8 18.8 15.4 12.8 14.5 22.2 14.1 16.0 13.6 18.9 10.5 9.8 26.8 43.4 10.5 7.0 14.2 15.8 16.1 13.5 45.6 11.9 7.6 15.2 17.5 11.7 17.5 17.4 25.0 25.9 7.0 10.4 12.9 11.6 9.6 13.4 5.5 14.4 3.2 15.1 13.4 11.4 16.5 9.6 1.6 10.0 17.6 11.8 9.2 4.6 7.1 4.6 13.8 8.8 14.2 14.9 6.5 20.2 5.5 6.1 7.9 5.5 13.4 10.2 0.5 9.6 6.6 6.2 6.9 6.9 4.4 20.8 4.6 7.1 8.3 16.1 5.8 0.1 13.4 10.2 2.9 6.6 4.8 18.5 12.7 9.7 8.2 11.4 0.2 4.7 4.0 10.0 6.3 3.6 9.9 8.7 9.2 4.5 5.8 9.8 21.2 7.9 34.5 8.7 9.5 4.1 5.2 5.0 3.7 11.2 9.6 0.6 7.0 4.3 6.0 5.9 8.1 17.6 0.1 11.8 0.0 1.6 0.7 0.0 10.0 0.2 0.5 0.2 3.2 9.2 9.4 0.2 4.6 7.1 11.9 13.3 9.7 21.3 10.5 9.8 14.2 15.8 15.2 14.4 SUPT16H "CDC68, FACT, FACTP140, FLJ10857, FLJ14010, SPT16/CDC68" ENSG00000092201 "SPT16 homolog, facilitates chromatin remodeling subunit" Q9Y5B9 14 21351472-21384266 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022551, HPA049787" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" Nucleoplasm "Nucleoli fibrillar center" "CAB022551: , HPA049787: " "unprognostic (1.65e-1)" "unprognostic (2.22e-1)" "unprognostic (3.52e-2)" "unprognostic (7.12e-2)" "unprognostic (7.32e-2)" "unprognostic (1.22e-2)" "unprognostic (1.38e-3)" "unprognostic (1.86e-1)" "unprognostic (7.65e-2)" "unprognostic (4.91e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (6.48e-3)" "unprognostic (1.02e-1)" "unprognostic (7.58e-3)" "unprognostic (9.05e-2)" "unprognostic (5.87e-3)" 21.6 18.3 16.3 21.6 26.2 21.5 21.3 39.1 27.9 22.8 21.3 14.4 20.7 13.5 31.5 18.5 20.9 23.7 14.5 15.9 17.9 16.2 17.7 14.1 17.1 28.0 18.8 22.8 29.0 15.7 40.3 24.0 18.9 28.6 18.8 21.5 11.3 19.3 20.5 21.4 22.1 19.9 27.4 18.9 22.6 19.1 24.9 19.0 32.7 20.3 17.0 29.5 24.6 20.7 23.3 17.1 21.1 20.4 23.2 26.8 16.7 29.9 28.3 39.3 28.8 17.8 17.8 28.0 27.1 21.7 33.2 31.3 27.4 27.1 63.7 10.4 19.7 32.1 49.7 24.5 50.3 20.2 21.2 38.6 25.9 38.4 18.2 54.5 28.8 15.6 15.1 27.6 31.3 22.4 31.7 27.4 27.4 19.4 50.9 16.6 43.8 28.1 55.1 44.9 34.4 13.3 33.2 39.4 33.6 43.9 26.4 16.5 14.6 25.9 18.9 29.1 24.3 18.0 29.3 27.4 45.7 64.2 10.7 32.2 22.0 21.1 13.1 19.6 22.8 17.3 26.8 23.3 21.8 25.3 17.1 21.3 25.0 25.1 11.0 23.2 20.4 16.1 20.3 16.7 16.3 26.2 39.1 27.9 17.9 16.2 18.8 22.8 28.6 19.0 SUPV3L1 SUV3 ENSG00000156502 "Suv3 like RNA helicase" Q8IYB8 10 69180232-69209099 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038380, HPA038405" Supported Supported Mitochondria Mitochondria "HPA038380: AB_2675983, HPA038405: AB_10675797" "unprognostic (4.70e-2)" "unprognostic (1.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-2)" "unprognostic (3.74e-2)" "unprognostic (3.32e-2)" "unprognostic (1.44e-2)" "unprognostic (1.78e-1)" "unprognostic (1.57e-1)" "unprognostic (9.47e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (5.48e-3)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (5.27e-2)" "unprognostic (1.33e-1)" 12.8 17.0 11.1 12.6 17.3 26.1 17.7 21.9 19.9 10.8 14.4 12.6 7.8 11.2 13.5 12.4 13.2 11.9 12.6 19.2 12.0 11.3 16.4 22.2 9.6 15.2 9.9 13.1 15.8 18.2 15.4 14.7 10.9 16.1 11.4 16.7 12.4 11.8 13.9 31.1 15.6 12.5 13.9 9.9 15.5 13.0 26.6 9.9 12.7 14.1 13.4 14.8 12.4 11.6 10.1 7.3 5.6 7.7 7.4 13.7 6.2 11.3 7.9 7.1 21.8 8.0 6.8 9.4 7.0 10.9 14.3 13.5 20.3 9.6 20.4 5.8 7.1 13.0 17.1 11.0 13.8 8.5 13.4 8.9 6.2 10.7 20.3 21.1 6.8 8.6 13.9 13.1 30.2 8.2 23.2 10.6 7.8 7.3 12.8 13.1 8.5 43.4 11.8 10.1 8.9 6.5 5.5 10.2 7.7 9.7 20.4 18.5 6.3 9.3 5.1 5.7 10.3 8.6 13.6 8.4 9.8 19.0 9.4 22.4 3.6 5.6 5.2 4.3 12.3 7.7 13.7 10.1 8.9 10.5 7.3 8.3 9.9 10.6 0.9 7.4 5.2 4.0 8.7 6.2 11.1 17.3 21.9 19.9 12.0 11.3 9.9 13.1 16.1 9.9 SUV39H2 "FLJ23414, KMT1B" ENSG00000152455 "Suppressor of variegation 3-9 homolog 2" Q9H5I1 10 14878820-14904315 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045901, HPA057554" Enhanced Approved Mitochondria Mitochondria "HPA045901: AB_10960702, HPA057554: " "prognostic unfavourable (5.55e-4)" "unprognostic (1.45e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-3)" "unprognostic (6.80e-2)" "unprognostic (1.23e-3)" "prognostic unfavourable (2.01e-6)" "unprognostic (1.06e-1)" "unprognostic (9.15e-2)" "unprognostic (3.59e-3)" "unprognostic (2.42e-1)" "unprognostic (4.13e-3)" "prognostic unfavourable (5.71e-5)" "unprognostic (2.71e-2)" "unprognostic (1.40e-1)" "unprognostic (5.55e-2)" "unprognostic (1.39e-1)" 3.0 2.9 4.7 3.4 7.4 4.9 5.2 20.0 8.6 3.1 3.8 1.6 2.1 3.2 3.8 2.3 4.0 3.0 3.2 2.4 5.4 2.8 3.5 3.8 2.7 3.6 3.3 4.4 4.2 2.4 2.4 6.3 5.1 3.3 3.9 4.7 1.6 2.4 3.6 2.4 3.3 2.9 3.7 3.0 3.4 2.7 41.8 4.4 10.3 2.8 4.9 4.0 3.3 2.8 0.8 3.1 0.5 1.8 5.6 4.0 0.8 13.7 13.1 21.9 12.5 4.1 4.9 8.6 7.5 4.6 13.9 19.8 19.5 7.9 11.0 6.8 4.4 9.7 16.2 9.0 17.2 11.2 10.8 16.6 9.2 12.0 2.4 7.4 8.0 2.4 3.2 14.1 4.4 9.6 21.4 7.4 10.3 13.4 14.8 2.1 13.5 3.5 18.3 14.5 8.9 5.9 6.5 7.3 8.1 11.6 7.2 6.3 12.8 6.4 5.6 10.1 16.2 12.2 11.8 4.3 16.1 25.3 6.2 8.1 6.4 0.5 0.4 0.3 2.8 1.8 4.0 0.8 2.4 3.5 2.2 0.6 3.8 3.6 0.3 5.6 0.5 3.1 3.7 0.8 4.7 7.4 20.0 8.6 5.4 2.8 3.3 4.4 3.3 4.4 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 38.5" "Cell line enhanced" "Detected in many" "Daudi: 38.7;HEL: 22.3;HL-60: 30.8;HMC-1: 20.5;REH: 25.8;THP-1: 23.7;U-698: 18.3;U-937: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 21.4;eosinophil: 23.3;intermediate monocyte: 19.0;memory B-cell: 23.1;myeloid DC: 24.9;naive B-cell: 17.5;neutrophil: 32.8;NK-cell: 8.7;non-classical monocyte: 16.4;plasmacytoid DC: 18.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" 1000000 "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.2 3.3 6.0 38.1 9.6 18.2 6.7 1.1 4.5 3.7 10.3 6.7 1.5 12.3 2.3 6.7 16.2 6.9 6.6 5.5 7.2 3.2 8.6 2.5 13.7 36.4 9.1 2.5 2.1 8.9 25.9 3.1 5.0 6.1 4.1 8.3 2.8 8.9 1.8 1.4 8.3 22.2 3.5 11.3 38.5 7.4 5.5 7.9 30.5 18.1 7.8 32.2 8.6 7.5 23.1 24.9 32.8 21.4 8.7 0.1 10.2 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 38.7 1.1 0.0 6.0 0.8 3.2 0.0 0.0 5.3 22.3 0.0 0.0 0.0 30.8 20.5 0.0 4.4 0.0 0.4 0.0 0.6 3.1 0.0 4.7 0.0 13.5 0.2 0.0 25.8 0.0 10.6 0.8 5.8 2.0 1.8 0.0 2.7 0.0 2.5 23.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.3 0.0 21.7 0.0 1.4 21.4 23.3 0.1 19.0 0.1 23.1 0.0 0.0 24.9 17.5 0.0 0.0 32.8 8.7 16.4 18.5 0.0 10.2 6.0 9.6 1.1 4.5 7.2 3.2 9.1 2.5 6.1 7.9 SYNJ1 "INPP5G, PARK20" ENSG00000159082 "Synaptojanin 1" O43426 21 32628759-32728048 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, RNA-binding" "Disease mutation, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011916 Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Cytosol" Centrosome "HPA011916: AB_1857692" "unprognostic (6.84e-2)" "unprognostic (8.64e-2)" "unprognostic (5.76e-2)" "unprognostic (6.44e-2)" "unprognostic (1.27e-1)" "prognostic favourable (4.43e-4)" "unprognostic (1.45e-1)" "unprognostic (3.73e-3)" "unprognostic (1.63e-1)" "unprognostic (6.22e-3)" "unprognostic (1.84e-2)" "prognostic unfavourable (2.58e-4)" "unprognostic (1.28e-1)" "unprognostic (6.36e-2)" "unprognostic (5.97e-2)" "unprognostic (1.79e-1)" "unprognostic (2.92e-1)" 5.5 6.8 13.6 5.0 25.9 20.6 4.2 19.5 39.0 4.8 4.8 6.5 0.8 3.9 4.6 5.3 3.9 4.0 5.2 5.2 18.3 18.2 7.4 5.5 6.5 5.7 16.6 18.4 4.6 4.5 10.6 10.9 9.3 33.5 3.6 5.5 7.0 3.8 4.0 4.4 5.0 4.6 5.0 7.3 6.0 4.2 9.0 5.7 3.2 6.8 1.5 4.8 4.7 3.3 0.4 3.1 11.5 6.0 0.5 3.0 1.1 5.5 2.8 5.1 5.6 8.9 7.2 10.3 11.5 6.6 7.0 5.9 6.3 2.6 2.0 3.9 6.9 5.2 9.1 6.7 8.4 6.5 8.7 13.8 9.0 3.5 4.8 5.7 12.3 4.0 5.0 12.2 6.2 10.9 10.3 11.9 9.0 5.6 5.3 4.7 3.6 6.3 5.8 11.1 7.2 7.4 4.0 5.8 4.5 14.1 9.0 5.5 7.8 7.4 12.1 10.9 5.4 8.7 6.3 6.2 7.2 4.3 8.2 10.8 8.6 3.7 3.4 7.9 1.6 6.0 2.7 0.2 2.4 2.6 3.1 0.4 2.9 2.8 11.5 0.5 5.3 1.6 3.0 1.1 13.6 25.9 19.5 28.7 18.3 18.2 16.6 18.4 33.5 5.7 SYNJ2 INPP5H ENSG00000078269 "Synaptojanin 2" O15056 6 157981887-158099176 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 62.0" "Cell line enhanced" "Detected in many" "TIME: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031575 Approved Approved Microtubules,Cytosol Microtubules Cytosol "HPA031575: AB_10604101" "prognostic unfavourable (2.63e-4)" "unprognostic (1.94e-2)" "unprognostic (7.61e-2)" "unprognostic (1.25e-2)" "unprognostic (1.48e-2)" "unprognostic (7.68e-2)" "unprognostic (1.24e-1)" "unprognostic (7.06e-2)" "unprognostic (2.91e-1)" "unprognostic (7.29e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "prognostic unfavourable (4.02e-6)" "unprognostic (1.66e-2)" "unprognostic (3.75e-2)" "unprognostic (1.75e-1)" "unprognostic (9.45e-2)" 2.8 3.9 12.2 4.9 25.1 15.3 6.7 3.0 18.7 3.9 8.7 50.5 3.7 5.8 5.2 9.4 6.0 4.6 8.0 8.5 17.8 10.9 3.2 4.0 2.8 4.4 46.8 8.8 2.9 6.6 1.1 2.9 2.6 33.0 5.3 8.9 1.4 13.5 5.1 4.3 3.1 5.6 6.6 62.0 3.3 7.0 6.5 24.4 3.0 4.4 1.4 5.3 5.9 3.0 3.2 1.1 9.3 1.3 2.4 3.8 0.8 5.9 20.9 1.7 2.7 1.3 4.3 9.3 11.0 22.4 13.2 15.6 10.7 5.1 0.2 7.5 21.2 5.7 3.7 6.9 15.4 8.3 3.4 11.6 10.9 11.3 2.5 4.0 12.6 2.2 3.7 20.1 4.7 22.9 8.8 2.6 6.0 2.8 5.0 4.5 2.0 11.7 2.2 7.2 5.3 4.4 6.9 13.3 0.7 8.5 5.4 2.1 4.2 2.5 40.5 10.0 10.3 23.1 13.3 1.1 2.8 0.3 18.8 6.4 6.9 4.5 1.3 1.1 1.9 0.6 3.8 1.9 2.6 1.7 1.1 3.2 2.2 1.7 9.3 2.4 0.8 1.1 2.1 0.8 12.2 25.1 3.0 18.7 17.8 10.9 46.8 8.8 33.0 24.4 SYVN1 "DER3, HRD1" ENSG00000162298 "Synoviolin 1" Q86TM6 11 65121780-65134533 "Enzymes, Predicted membrane proteins" "Stress response, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005480, HPA024300, CAB037030" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" Nucleoplasm "Endoplasmic reticulum, Plasma membrane" "CAB037030: AB_1840939, HPA005480: AB_1079084, HPA024300: AB_1851073" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.17e-2)" "unprognostic (2.85e-2)" "prognostic favourable (6.88e-4)" "unprognostic (7.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (1.56e-2)" "unprognostic (4.89e-1)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" 13.8 20.8 11.0 33.0 15.3 13.8 14.9 13.3 19.3 15.1 14.2 21.0 20.2 13.2 16.0 21.1 14.4 16.1 15.3 12.9 11.3 10.0 16.4 78.0 14.2 28.9 18.2 8.7 17.1 68.1 24.4 21.0 20.9 14.4 15.0 15.4 13.3 48.9 22.6 16.7 14.4 19.6 13.6 12.8 27.1 18.3 14.4 14.9 10.3 23.5 8.0 42.2 13.3 12.6 17.5 13.0 11.6 5.4 2.2 5.5 3.8 8.5 10.9 6.6 8.9 16.8 9.6 6.5 8.8 9.1 11.3 8.0 5.9 14.9 48.0 12.1 11.3 13.2 7.1 8.9 9.4 7.4 5.4 7.5 12.7 13.2 20.4 11.3 13.7 12.2 16.2 9.9 22.5 7.3 9.4 24.6 6.6 12.6 4.9 8.2 7.1 7.6 8.4 5.5 19.3 7.1 8.4 4.3 8.8 8.2 20.3 14.2 15.1 7.4 6.9 7.9 5.2 14.0 5.9 49.2 34.0 55.5 10.6 5.8 8.8 11.6 5.4 9.3 5.5 3.3 5.0 15.4 3.9 5.1 3.1 17.5 2.9 3.0 5.2 2.2 3.2 13.0 3.6 3.8 11.0 15.3 13.3 19.3 11.3 10.0 18.2 8.7 14.4 14.9 TAF1 "BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250" ENSG00000147133 "TATA-box binding protein associated factor 1" P21675 X 71366239-71532374 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dystonia, Mental retardation, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA001075, CAB016283" Supported Enhanced Nucleoplasm Nucleoplasm "CAB016283: AB_671202, HPA001075: AB_1080179" "unprognostic (2.95e-2)" "unprognostic (1.77e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-2)" "unprognostic (1.88e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "prognostic favourable (6.54e-4)" "unprognostic (2.68e-2)" "unprognostic (3.43e-2)" "unprognostic (2.03e-1)" "unprognostic (5.59e-2)" "prognostic unfavourable (6.03e-4)" "unprognostic (1.14e-2)" "unprognostic (1.41e-1)" "unprognostic (1.82e-2)" "unprognostic (2.56e-2)" 20.1 16.2 15.0 17.1 19.8 16.3 17.7 20.7 18.0 20.7 15.5 23.8 17.1 10.0 25.4 17.1 14.4 19.1 16.1 12.9 15.4 12.0 11.9 12.9 13.8 17.8 18.5 16.5 23.9 17.5 25.5 19.3 15.4 17.3 16.9 15.4 20.8 14.5 16.1 19.6 16.8 17.1 18.3 17.2 21.3 15.8 12.2 21.3 19.4 20.1 12.0 18.7 18.4 15.8 5.0 4.7 5.2 4.8 4.2 4.9 1.8 11.2 9.8 11.2 7.5 9.0 15.6 7.0 8.4 7.8 8.9 7.4 7.3 6.8 10.5 7.2 9.4 10.7 15.6 6.7 11.4 6.9 13.7 12.5 12.9 7.2 6.5 23.7 12.1 9.1 6.8 9.5 18.0 9.2 17.0 25.5 9.0 7.9 13.1 10.5 12.9 12.9 12.1 22.8 12.8 6.0 14.6 5.9 9.2 23.4 8.2 10.4 6.0 12.6 11.6 10.5 8.8 8.4 5.8 10.9 10.1 13.6 5.8 19.1 7.8 4.4 4.1 1.1 4.4 2.8 3.8 3.0 4.6 4.5 4.7 5.0 4.4 4.9 5.2 4.2 4.8 3.5 3.1 1.8 15.0 19.8 20.7 18.0 15.4 12.0 18.5 16.5 17.3 21.3 TALDO1 ENSG00000177156 "Transaldolase 1" P37837 11 747329-765024 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pentose shunt" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 204.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 148.6;neutrophil: 204.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048089 Approved Nucleoplasm,Cytosol 39000000 Nucleoplasm Cytosol "HPA048089: AB_2680260" "unprognostic (5.29e-2)" "unprognostic (1.78e-2)" "unprognostic (3.47e-1)" "unprognostic (9.65e-3)" "unprognostic (2.97e-2)" "unprognostic (4.15e-2)" "prognostic unfavourable (2.29e-4)" "unprognostic (9.78e-2)" "unprognostic (4.27e-2)" "unprognostic (1.74e-1)" "unprognostic (7.97e-3)" "unprognostic (2.94e-1)" "unprognostic (1.59e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (2.37e-1)" "unprognostic (1.16e-3)" 39.0 24.2 26.6 34.8 31.3 117.4 44.2 20.6 38.3 27.7 28.5 51.2 18.8 34.2 20.4 20.7 90.0 23.2 33.2 37.5 29.2 23.6 45.8 48.4 37.9 60.0 46.5 26.6 23.4 31.9 14.6 15.8 34.3 30.7 28.3 23.7 15.5 38.3 19.5 31.2 38.4 29.4 40.4 47.5 45.6 35.8 14.8 33.0 34.1 42.2 82.4 43.1 51.4 37.5 8.5 36.1 204.6 60.8 5.9 10.4 45.3 41.9 53.1 15.4 29.1 31.9 18.6 45.4 31.9 41.1 31.6 26.1 22.6 91.6 23.4 43.4 41.8 45.4 24.3 34.4 16.5 30.6 49.3 40.5 20.6 78.8 34.1 64.7 60.5 15.2 27.8 21.2 17.2 43.4 52.5 39.2 29.3 40.1 37.6 76.8 24.2 43.1 31.4 18.1 83.9 57.4 24.5 38.0 13.3 29.7 61.5 30.9 29.2 49.3 57.6 14.5 13.6 11.4 29.9 16.6 16.1 27.8 32.1 56.6 58.4 64.7 60.8 148.6 5.6 23.2 6.1 8.5 7.5 6.8 36.1 6.8 6.1 5.7 204.6 5.9 23.2 14.8 10.4 45.3 26.6 31.3 20.6 38.3 29.2 23.6 46.5 26.6 30.7 33.0 TAMM41 "C3orf31, DKFZp434E0519, MGC16471" ENSG00000144559 "TAM41 mitochondrial translocator assembly and maintenance homolog" Q96BW9 3 11790442-11846919 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036834, HPA044861" Uncertain Approved Cytosol Cytosol "HPA036834: AB_10672270, HPA044861: " "unprognostic (2.40e-2)" "unprognostic (4.41e-2)" "prognostic favourable (1.23e-4)" "unprognostic (4.45e-2)" "unprognostic (1.44e-2)" "unprognostic (5.60e-2)" "unprognostic (2.03e-5)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (7.33e-3)" "unprognostic (3.78e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-1)" "unprognostic (7.34e-2)" "unprognostic (3.59e-3)" 13.9 12.9 21.8 15.9 27.5 9.1 15.7 25.6 19.8 12.5 12.2 14.2 12.5 11.5 17.7 23.7 15.2 12.4 10.0 13.8 13.9 11.5 12.4 12.0 18.7 25.0 11.3 15.3 21.7 12.9 12.5 15.4 9.9 11.4 10.7 12.0 11.2 11.7 14.2 15.2 17.3 10.4 15.0 13.7 12.3 10.1 14.1 14.8 12.7 10.8 8.4 17.4 13.8 13.8 8.7 8.9 7.7 7.1 7.1 11.3 5.0 4.1 7.9 9.6 6.6 10.4 13.2 17.8 6.5 4.6 9.9 9.9 9.4 6.9 16.0 9.5 6.7 5.2 16.0 9.7 12.9 5.9 15.2 9.5 7.6 10.9 12.2 17.4 5.1 7.5 14.4 9.3 10.5 15.3 13.9 4.9 12.6 12.1 9.8 13.0 7.7 16.8 9.8 5.5 14.1 15.1 10.3 4.4 3.8 5.6 7.3 10.7 9.5 7.9 4.0 5.2 5.9 15.5 9.2 3.8 9.4 8.3 6.3 14.9 4.7 2.2 5.3 7.7 7.2 3.6 9.2 8.7 11.3 7.0 8.9 8.0 10.4 10.6 0.2 7.1 7.1 6.6 8.7 5.0 21.8 27.5 25.6 19.8 13.9 11.5 11.3 15.3 11.4 14.8 TAOK1 "FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1" ENSG00000160551 "TAO kinase 1" Q7L7X3 17 29390464-29551904 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007669 Approved Approved Vesicles 13000 Vesicles "HPA007669: AB_1080201" "unprognostic (1.46e-1)" "unprognostic (7.15e-3)" "unprognostic (2.70e-2)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (4.85e-2)" "unprognostic (1.28e-2)" "unprognostic (4.31e-2)" "unprognostic (1.15e-1)" "unprognostic (6.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.85e-2)" "unprognostic (5.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" 17.2 11.5 19.1 11.9 25.0 12.7 13.3 20.1 24.4 15.8 11.9 22.2 7.9 7.1 14.9 10.8 12.7 11.0 11.6 15.3 18.7 15.5 13.6 10.6 13.2 11.1 30.0 17.6 13.5 9.3 31.7 13.7 14.3 21.8 12.0 10.7 10.9 11.1 13.3 15.0 13.8 9.8 17.7 21.0 13.0 10.8 14.3 23.5 11.7 17.7 6.0 11.2 14.5 17.1 2.4 4.8 5.5 2.1 1.4 3.0 0.9 13.6 24.3 19.2 8.2 14.3 18.1 8.1 12.9 13.8 11.9 12.5 13.1 4.8 8.5 12.7 21.0 10.7 17.5 8.9 21.4 17.6 12.9 13.5 14.1 7.0 10.4 14.9 12.5 11.9 11.5 17.5 18.0 16.2 13.8 7.7 15.5 9.1 11.7 5.5 8.1 6.2 10.9 27.1 5.9 11.2 19.7 10.6 13.0 22.2 20.8 13.4 15.0 13.8 23.5 18.2 14.8 15.9 18.0 7.1 15.3 9.8 13.3 9.4 16.4 1.7 1.9 1.5 2.0 2.1 1.6 1.6 2.0 2.4 1.7 2.4 3.0 2.2 5.5 1.4 1.9 4.8 1.2 0.9 19.1 25.0 20.1 22.7 18.7 15.5 30.0 17.6 21.8 23.5 TAOK2 "KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973641-29992261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010650 Approved Supported Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Cytosol" Nucleoli "HPA010650: AB_1080204" "unprognostic (7.30e-2)" "unprognostic (1.78e-1)" "prognostic unfavourable (2.51e-4)" "prognostic favourable (3.87e-5)" "unprognostic (8.46e-2)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-1)" "prognostic favourable (4.78e-4)" "unprognostic (3.85e-3)" "prognostic favourable (3.66e-4)" "unprognostic (7.42e-3)" "unprognostic (3.17e-1)" "unprognostic (7.47e-2)" "unprognostic (1.37e-1)" 27.8 24.1 26.2 15.1 26.7 12.3 17.7 29.2 30.6 13.5 13.6 21.5 11.8 18.5 16.8 13.0 12.4 14.1 15.1 17.6 25.0 18.2 13.9 10.4 23.0 14.4 22.1 22.7 15.8 16.3 26.2 18.7 22.5 20.7 13.6 9.6 15.0 17.1 15.9 22.8 20.0 19.3 14.8 14.9 26.3 16.0 21.2 20.2 14.0 15.9 9.8 11.5 12.8 18.0 2.6 3.3 4.8 2.8 2.0 3.2 2.0 11.2 21.5 11.8 18.5 13.8 9.3 18.1 20.6 11.0 14.0 13.1 17.2 15.0 12.2 17.5 14.8 17.5 10.7 10.4 7.5 18.9 22.7 13.1 21.7 17.2 10.1 12.8 25.2 10.9 9.0 14.8 6.0 23.3 11.7 12.4 13.3 20.7 14.9 18.3 11.4 14.5 27.7 17.1 11.3 8.8 10.6 13.9 11.1 11.8 15.8 6.1 19.8 14.6 32.5 24.1 11.2 17.1 11.9 18.1 11.6 11.5 14.8 14.8 17.5 1.3 2.8 1.5 2.9 2.7 3.1 2.0 2.9 2.6 1.8 2.6 1.6 1.4 4.8 2.0 1.4 3.3 3.2 2.0 26.2 26.7 29.2 30.6 25.0 18.2 22.1 22.7 20.7 20.2 TAOK3 "DPK, JIK, MAP3K18" ENSG00000135090 "TAO kinase 3" Q9H2K8 12 118149801-118372945 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017160 Approved Uncertain Mitochondria Mitochondria "HPA017160: AB_1851994" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-2)" "unprognostic (5.18e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-1)" "unprognostic (5.86e-2)" "unprognostic (1.00e-1)" "unprognostic (7.38e-2)" "unprognostic (2.76e-2)" "unprognostic (8.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.08e-2)" "unprognostic (4.14e-3)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" 14.6 16.2 31.9 24.1 31.0 30.8 14.6 44.3 33.5 11.6 21.2 17.2 10.3 23.1 15.2 11.4 16.0 9.8 16.9 15.1 27.8 31.7 14.0 15.3 19.4 26.3 25.7 20.8 17.5 10.9 20.2 23.6 11.9 20.7 25.6 21.3 12.0 13.6 14.6 18.5 17.0 31.6 15.3 23.7 24.2 20.9 8.9 28.6 28.3 18.1 9.9 26.9 18.5 18.3 20.9 22.4 38.2 37.8 36.4 27.8 17.1 8.2 5.7 4.3 3.7 10.5 12.8 4.9 8.6 9.8 5.0 6.6 2.9 12.8 25.2 2.8 11.5 7.4 3.7 7.7 7.9 9.1 3.2 29.7 2.9 3.7 12.3 30.4 41.9 8.7 9.3 15.9 23.3 16.1 17.2 3.0 9.2 5.8 16.0 20.0 1.6 3.0 9.4 5.8 2.6 4.7 14.3 0.8 4.2 8.0 3.6 11.0 7.4 22.8 24.9 8.7 1.5 8.1 7.4 2.9 2.8 19.9 12.3 21.0 11.6 38.2 17.0 37.6 27.8 23.3 26.2 20.9 21.2 24.1 22.4 19.3 18.8 24.5 37.7 36.4 37.8 20.9 19.3 17.1 31.9 31.0 44.3 33.5 27.8 31.7 25.7 20.8 20.7 28.6 TARS ENSG00000113407 "Threonyl-tRNA synthetase" P26639 5 33440696-33469539 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037425 Approved Supported "Actin filaments,Cytosol" 170000 Cytosol "Actin filaments" "HPA037425: AB_10672279" "prognostic unfavourable (6.14e-5)" "unprognostic (5.13e-2)" "unprognostic (9.04e-2)" "prognostic unfavourable (5.17e-4)" "unprognostic (9.10e-2)" "unprognostic (1.07e-3)" "prognostic unfavourable (9.88e-7)" "unprognostic (1.43e-1)" "unprognostic (1.61e-1)" "unprognostic (2.65e-3)" "unprognostic (5.97e-3)" "unprognostic (1.56e-2)" "prognostic unfavourable (9.63e-4)" "unprognostic (1.37e-1)" "unprognostic (5.15e-2)" "unprognostic (1.18e-1)" "unprognostic (7.25e-2)" 17.4 25.6 10.2 16.0 13.1 19.2 17.7 14.4 17.2 12.7 22.1 12.3 18.7 11.6 18.3 19.7 31.0 12.2 11.9 19.1 10.3 10.9 19.2 57.0 17.2 12.7 17.5 7.8 21.3 27.6 21.3 27.0 18.5 16.8 13.9 24.7 10.8 42.1 15.8 25.1 11.7 21.7 21.2 19.5 18.3 21.2 9.6 15.4 17.6 22.8 27.3 21.2 21.8 21.9 13.1 16.0 14.2 12.6 24.0 15.0 9.7 29.4 24.7 20.7 29.2 13.7 25.9 30.1 33.1 28.1 25.1 28.4 30.1 18.4 11.7 12.1 27.3 21.0 44.1 32.7 51.7 17.3 16.0 17.0 63.3 17.2 42.6 27.3 18.2 24.7 52.7 34.5 44.7 26.8 33.3 31.6 32.0 16.3 21.3 9.4 22.0 18.3 18.1 36.7 17.2 28.5 23.6 12.1 13.8 30.7 22.5 21.9 11.8 24.4 14.1 19.7 29.4 15.5 23.2 18.6 36.6 18.3 22.0 36.1 21.3 14.2 11.6 10.5 15.0 12.6 14.1 13.1 12.7 15.0 16.0 11.5 11.6 14.7 1.5 24.0 10.1 8.8 12.1 9.7 10.2 13.1 14.4 17.2 10.3 10.9 17.5 7.8 16.8 15.4 TARS2 "FLJ12528, TARSL1" ENSG00000143374 "Threonyl-tRNA synthetase 2, mitochondrial" Q9BW92 1 150487364-150507609 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028626 Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" "Nucleoplasm, Cytosol" "Intermediate filaments" "HPA028626: AB_10601719" "unprognostic (2.48e-1)" "unprognostic (7.75e-2)" "unprognostic (6.68e-2)" "unprognostic (3.75e-3)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "unprognostic (4.93e-2)" "unprognostic (2.14e-1)" "unprognostic (9.35e-2)" "unprognostic (4.26e-2)" "unprognostic (2.25e-1)" "unprognostic (3.76e-2)" "unprognostic (9.23e-2)" "unprognostic (9.29e-3)" "unprognostic (4.19e-2)" "unprognostic (1.14e-2)" "unprognostic (5.55e-2)" 10.7 21.1 16.5 10.5 17.8 9.2 11.3 17.5 21.4 10.2 10.9 14.8 12.9 9.4 10.5 14.7 15.7 13.0 11.8 20.9 18.1 12.3 15.6 26.8 9.1 14.0 15.0 19.7 13.3 11.5 20.4 12.2 9.4 16.5 9.8 12.5 13.3 11.3 10.9 36.0 13.3 10.5 10.9 13.8 15.1 12.4 10.7 16.6 10.6 12.3 12.2 15.7 12.5 10.8 21.5 17.4 20.4 18.6 21.5 20.9 12.2 17.0 14.3 9.7 14.5 10.9 10.0 18.4 8.3 9.1 16.5 16.7 11.6 16.0 24.8 18.4 6.2 17.8 23.4 19.3 12.7 14.9 20.3 11.7 13.5 11.7 10.8 16.1 18.0 8.8 16.2 12.5 17.1 10.6 20.3 17.4 11.5 20.7 13.6 13.2 11.9 21.3 14.1 12.3 30.6 11.2 8.1 13.7 16.0 12.6 27.9 19.6 22.5 25.3 6.2 9.7 10.3 7.9 14.0 16.8 19.8 18.7 14.4 18.8 9.3 15.1 11.0 20.4 15.7 18.3 15.6 21.5 15.4 15.5 17.4 18.6 15.1 15.8 1.7 21.5 18.6 11.7 20.9 12.2 16.5 17.8 17.5 21.4 18.1 12.3 15.0 19.7 16.5 16.6 TARSL2 FLJ25005 ENSG00000185418 "Threonyl-tRNA synthetase like 2" A2RTX5 15 101653598-101724604 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 47.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 9.7;NK-cells: 9.0;T-cells: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066697 Approved Approved Cytosol Cytosol "HPA066697: " "unprognostic (9.33e-3)" "unprognostic (2.13e-2)" "unprognostic (1.88e-1)" "unprognostic (2.54e-1)" "unprognostic (8.44e-2)" "unprognostic (1.92e-1)" "unprognostic (8.45e-2)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (7.77e-2)" "unprognostic (2.26e-3)" "unprognostic (9.76e-3)" "unprognostic (4.00e-2)" "unprognostic (2.23e-1)" "unprognostic (7.52e-2)" "unprognostic (6.48e-3)" "unprognostic (2.79e-2)" 7.4 6.9 15.1 6.4 20.2 4.8 7.5 15.8 16.2 7.2 7.1 20.2 5.5 6.2 6.5 6.0 6.3 6.5 5.9 21.0 16.9 13.8 8.3 5.9 6.2 6.5 20.0 11.2 11.0 9.8 12.9 10.5 3.7 15.7 9.2 6.2 4.0 7.1 9.7 47.7 4.9 6.5 6.9 19.9 6.2 8.5 5.4 18.9 3.9 9.6 8.0 7.1 7.0 7.8 9.7 2.0 1.6 1.7 9.0 6.1 1.0 2.1 4.1 7.0 3.8 7.5 5.9 3.5 7.5 5.0 5.9 3.7 5.9 2.0 2.8 3.0 9.1 6.3 12.3 4.3 5.4 3.3 19.7 6.9 2.6 4.7 3.5 3.1 1.4 4.1 4.0 2.7 3.4 4.2 6.8 6.1 5.8 3.6 1.7 6.1 8.5 2.9 3.5 10.6 7.3 4.9 2.2 11.2 6.9 10.1 3.9 4.1 2.5 6.4 5.6 2.8 6.7 5.7 2.4 8.6 9.6 3.5 7.3 5.7 5.2 0.9 1.1 1.6 3.4 1.7 3.4 4.8 6.1 5.2 0.8 9.7 5.9 3.2 0.3 9.0 0.7 2.0 1.0 1.0 15.1 20.2 15.8 16.2 16.9 13.8 20.0 11.2 15.7 18.9 TBCK "HSPC302, MGC16169" ENSG00000145348 "TBC1 domain containing kinase" Q8TEA7 4 106041599-106321495 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 24.8;BJ hTERT+ SV40 Large T+ RasG12V: 43.6;HBF TERT88: 29.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039951, HPA051611" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "HPA039951: AB_10795300, HPA051611: " "unprognostic (1.65e-1)" "unprognostic (2.60e-2)" "unprognostic (8.47e-2)" "unprognostic (1.12e-1)" "unprognostic (8.06e-2)" "unprognostic (1.13e-3)" "unprognostic (1.55e-1)" "unprognostic (3.81e-1)" "unprognostic (8.68e-2)" "unprognostic (1.85e-1)" "unprognostic (3.67e-2)" "unprognostic (1.80e-1)" "prognostic favourable (3.20e-4)" "unprognostic (8.17e-3)" "unprognostic (1.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.29e-1)" 12.8 19.0 14.2 7.6 15.2 3.4 10.0 16.3 15.2 13.5 8.3 10.0 11.0 4.4 10.9 14.9 10.6 13.0 13.2 9.3 12.1 11.1 17.8 10.5 9.6 6.9 15.0 8.5 17.5 8.2 12.6 24.2 13.7 12.1 11.9 9.1 9.0 9.1 14.6 4.2 8.5 7.2 13.3 10.3 8.5 8.1 12.0 13.8 18.5 13.9 4.6 8.9 14.5 10.7 10.7 6.3 11.9 6.8 5.9 8.4 4.2 0.9 2.5 5.1 1.9 19.2 12.0 0.9 3.8 6.2 24.8 43.6 4.4 3.8 1.7 5.8 13.0 2.2 3.4 4.7 29.8 2.3 1.0 5.3 2.0 4.6 5.0 2.2 3.1 11.2 3.9 2.3 3.9 6.4 4.1 2.1 7.5 3.3 2.8 2.0 1.2 1.7 2.1 3.2 3.5 6.5 4.4 2.7 2.2 3.4 2.4 3.3 3.3 4.8 3.7 4.4 2.2 1.0 1.9 1.0 2.8 3.7 6.0 3.2 2.3 11.9 6.4 6.3 6.2 6.8 7.2 6.2 6.8 8.4 6.3 10.7 7.4 6.7 0.5 5.9 4.6 6.1 6.7 4.2 14.2 15.2 16.3 15.2 12.1 11.1 15.0 8.5 12.1 13.8 TBK1 NAK ENSG00000183735 "TANK binding kinase 1" Q9UHD2 12 64451880-64502108 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease mutation, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045797, HPA060211" Uncertain Enhanced Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA045797: , HPA060211: " "unprognostic (4.73e-2)" "unprognostic (8.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.90e-1)" "unprognostic (1.94e-1)" "unprognostic (1.28e-1)" "prognostic unfavourable (3.30e-4)" "unprognostic (1.26e-1)" "prognostic unfavourable (3.48e-4)" "unprognostic (1.69e-1)" "unprognostic (2.54e-2)" "unprognostic (1.24e-2)" "prognostic unfavourable (4.20e-6)" "unprognostic (4.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.26e-2)" "unprognostic (9.56e-3)" 19.1 23.3 13.7 16.8 17.1 32.3 19.1 17.8 20.5 14.9 18.3 10.0 14.1 18.0 17.0 15.1 15.3 13.8 15.6 11.7 14.7 15.6 15.4 20.8 17.8 18.3 20.2 13.6 15.6 11.1 13.1 27.2 40.6 21.1 16.3 12.9 10.1 15.0 18.3 24.8 12.1 21.4 17.2 18.8 24.6 14.5 27.9 16.9 3.4 13.3 12.6 16.7 18.4 19.6 9.7 8.2 22.5 11.9 16.3 11.8 5.9 13.4 15.5 8.8 12.9 15.8 16.0 19.5 14.8 21.5 13.9 13.3 8.7 8.2 18.9 12.9 16.0 12.7 11.4 12.4 16.5 17.3 10.8 20.2 11.2 12.0 17.4 20.6 25.3 12.0 11.4 13.9 13.4 18.5 15.5 27.5 17.9 16.5 0.6 16.2 17.7 9.1 9.6 9.8 18.2 15.2 24.5 7.4 10.7 19.5 20.0 14.3 20.5 15.0 17.1 12.6 12.2 10.1 14.4 17.4 30.3 18.4 15.9 11.4 16.2 22.5 7.3 16.6 11.0 11.9 11.8 9.7 8.0 11.0 8.2 7.6 2.8 7.1 15.1 16.3 10.6 1.9 9.5 5.9 13.7 17.1 17.8 20.5 14.7 15.6 20.2 13.6 21.1 16.9 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 67.1;lymphoid tissue: 51.7" "Cell line enhanced" "Detected in some" "NB-4: 34.7;PC-3: 11.1;RPTEC TERT1: 9.9;U-937: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "basophil: 38.1;classical monocyte: 44.5;eosinophil: 45.2;intermediate monocyte: 67.1;myeloid DC: 18.7;neutrophil: 38.8;non-classical monocyte: 56.4" "Group enriched" "Detected in all" 20 "dendritic cells: 18.7;granulocytes: 45.2;monocytes: 67.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031257, HPA031258, HPA031259" Enhanced 32000000 "HPA031257: , HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavourable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.5 7.7 6.6 17.6 8.9 13.8 5.4 1.5 5.6 3.7 6.3 13.9 0.8 6.5 3.2 4.1 3.4 5.0 13.9 3.7 7.6 5.7 6.1 8.1 20.3 43.9 12.6 2.0 2.5 3.1 1.4 3.5 9.0 9.0 5.2 8.6 4.4 8.2 2.6 1.6 1.9 9.3 7.9 19.3 51.7 7.1 2.0 12.7 7.5 2.4 2.2 6.1 9.3 2.5 1.3 18.7 45.2 67.1 1.5 2.2 25.1 0.1 3.0 0.1 0.0 0.6 1.9 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 4.5 0.3 8.2 0.0 0.0 0.8 2.7 7.3 1.0 0.0 0.0 0.4 1.0 0.2 1.0 0.3 0.0 1.0 34.7 0.1 11.1 1.3 0.0 0.5 9.9 0.0 0.1 0.5 0.1 0.0 0.3 0.0 6.6 0.9 0.2 0.1 0.6 0.5 2.3 0.4 0.1 0.2 28.2 0.8 38.1 44.5 45.2 1.1 67.1 1.7 1.3 2.2 0.6 18.7 0.5 0.3 0.2 38.8 1.5 56.4 3.3 2.0 25.1 6.6 8.9 1.5 5.6 7.6 5.7 12.6 2.0 9.0 12.7 TDG ENSG00000139372 "Thymine DNA glycosylase" Q13569 12 103965804-103988874 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052263 Supported Supported Nucleoplasm Nucleoplasm "HPA052263: " "unprognostic (3.15e-1)" "unprognostic (1.36e-1)" "unprognostic (9.89e-3)" "unprognostic (6.93e-2)" "unprognostic (3.66e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (6.27e-5)" "unprognostic (1.56e-2)" "prognostic unfavourable (6.90e-5)" "unprognostic (5.37e-2)" "unprognostic (1.82e-1)" "unprognostic (8.48e-2)" "prognostic unfavourable (1.90e-10)" "unprognostic (3.68e-1)" "unprognostic (2.90e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" 12.3 16.6 7.0 17.9 11.1 15.9 12.8 10.7 13.4 17.7 14.7 10.0 11.3 11.0 15.8 17.8 23.8 12.4 12.8 12.0 7.7 6.9 13.4 17.4 13.7 19.7 8.7 7.9 14.4 13.2 11.0 21.0 27.9 10.8 13.0 16.8 10.9 13.2 11.3 11.1 16.3 18.7 17.8 8.8 19.8 13.1 5.8 8.1 33.4 12.4 15.3 19.6 13.3 14.7 18.9 41.4 18.8 24.3 14.2 13.6 7.2 13.2 6.7 21.2 12.3 5.3 4.7 21.4 10.0 4.1 14.0 7.9 11.4 6.0 31.2 6.1 8.3 8.8 25.3 11.8 11.1 12.7 20.5 24.5 10.1 5.1 4.9 30.4 18.6 5.5 15.7 10.4 8.4 13.7 27.3 5.2 6.8 13.8 33.9 17.1 25.7 10.8 35.0 10.9 11.1 15.4 19.6 28.0 19.4 12.2 14.3 8.9 22.9 16.4 8.3 4.4 7.2 4.6 11.8 11.4 15.1 26.8 4.8 16.4 8.4 18.5 24.3 18.8 13.6 16.3 10.3 17.7 13.0 11.2 14.9 18.9 13.5 12.1 16.0 14.2 15.9 41.4 12.6 7.2 7.0 11.1 10.7 13.4 7.7 6.9 8.7 7.9 10.8 8.1 TDO2 "TDO, TPH2" ENSG00000151790 "Tryptophan 2,3-dioxygenase" P48775 4 155854738-155920406 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "liver: 187.9" "Cell line enhanced" "Detected in some" "EFO-21: 8.4;HDLM-2: 16.4;U-87 MG: 9.6" "Cancer enriched" "Detected in many" 18 "liver cancer: 35.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "cerebellum: 7.0;hippocampal formation: 5.9" "Not detected" "Not detected" HPA039611 Uncertain Uncertain "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA039611: " "unprognostic (1.10e-1)" "unprognostic (3.00e-3)" "unprognostic (3.84e-2)" "unprognostic (1.95e-1)" "unprognostic (7.06e-2)" "unprognostic (3.50e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (4.68e-8)" "unprognostic (7.99e-2)" "unprognostic (9.29e-3)" "unprognostic (1.28e-1)" "unprognostic (1.95e-2)" 0.2 0.5 0.2 2.5 0.5 0.0 0.1 0.1 2.0 0.1 0.2 0.0 0.1 0.6 0.1 0.2 0.2 0.1 0.3 0.1 1.5 0.2 0.2 187.9 0.8 2.9 0.2 0.7 0.1 0.1 0.0 5.8 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.1 1.1 0.4 0.2 1.5 0.3 0.1 0.0 0.0 0.1 0.0 0.4 1.2 0.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 8.4 0.0 0.0 0.1 0.0 0.0 16.4 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.8 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.3 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.1 0.3 0.4 0.0 2.6 0.0 0.0 9.6 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 2.0 1.5 0.2 0.2 0.7 0.1 0.0 TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269864 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 10.4;HMC-1: 16.4;U-266/70: 16.3;U-266/84: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 13.3;eosinophil: 11.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" "Plasma membrane" "HPA005733: AB_1857878, HPA024657: " "unprognostic (7.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (4.07e-3)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "prognostic favourable (7.12e-4)" "unprognostic (7.46e-3)" "unprognostic (7.83e-2)" "unprognostic (1.01e-4)" "unprognostic (4.24e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-2)" "unprognostic (4.96e-3)" 3.9 4.5 0.8 7.2 1.1 9.8 5.1 0.6 2.0 3.4 4.8 0.5 8.4 2.8 3.0 21.6 9.5 3.6 2.1 3.3 0.9 0.9 4.0 5.7 6.4 7.0 1.5 0.3 2.9 2.9 2.6 6.4 2.0 3.2 2.0 2.5 3.0 6.8 4.7 2.1 8.1 6.5 3.0 1.2 6.7 2.2 5.5 0.6 4.4 4.4 5.8 11.1 3.2 6.5 0.9 1.3 13.3 0.6 2.9 0.4 0.3 2.3 0.6 0.0 0.0 0.0 0.0 0.1 0.4 1.8 1.0 2.2 0.0 1.7 1.5 1.6 0.0 0.5 0.9 0.0 1.5 0.1 0.7 10.4 0.7 0.1 0.0 1.7 16.4 0.0 0.2 1.4 0.0 0.0 5.7 0.4 3.2 0.7 1.0 3.7 0.3 0.7 2.4 2.2 0.0 2.8 0.7 0.0 0.2 0.5 0.2 0.4 0.6 3.3 0.0 0.0 0.0 2.2 0.0 16.3 11.6 2.1 0.0 2.3 0.1 13.3 0.5 11.0 0.1 0.6 0.3 0.9 0.1 0.4 1.3 0.6 0.4 0.4 0.4 2.9 0.1 0.1 0.0 0.3 0.8 1.1 0.6 2.0 0.9 0.9 1.5 0.3 3.2 0.6 TECR "GPSN2, MRT14, SC2, TER" ENSG00000099797 "Trans-2,3-enoyl-CoA reductase" Q9NZ01 19 14517085-14565980 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029780, HPA056488" Supported Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA029780: AB_10603348, HPA056488: AB_2683149" "unprognostic (9.73e-2)" "unprognostic (3.69e-3)" "unprognostic (1.55e-1)" "unprognostic (8.08e-3)" "unprognostic (1.20e-1)" "unprognostic (3.96e-2)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (9.16e-2)" "unprognostic (1.29e-1)" "unprognostic (5.05e-2)" "unprognostic (3.65e-3)" "unprognostic (2.53e-3)" "unprognostic (2.34e-1)" "unprognostic (2.07e-2)" "prognostic unfavourable (2.60e-4)" 32.8 43.2 45.0 15.0 43.7 23.0 26.2 51.7 70.8 34.9 26.1 64.5 40.1 37.8 16.5 38.2 89.6 32.4 19.0 22.3 42.9 38.3 29.0 45.9 20.7 17.8 45.6 34.7 25.0 37.0 95.0 20.9 68.5 50.4 23.9 21.7 34.5 69.8 42.0 121.4 89.5 34.8 13.8 53.3 20.0 24.5 59.6 40.2 29.8 33.5 40.7 49.5 18.3 43.8 21.7 30.2 10.7 22.8 34.3 60.6 32.7 38.8 29.0 27.7 31.2 40.5 18.5 29.3 11.3 32.2 36.6 45.6 38.5 45.0 20.9 23.9 23.8 60.6 29.2 46.2 14.8 34.2 25.1 35.5 43.5 42.4 24.4 25.1 27.1 27.4 37.0 32.2 17.7 17.2 22.7 72.1 18.7 48.9 29.5 43.8 29.0 31.4 27.5 18.1 92.4 49.7 21.0 34.6 21.2 19.0 51.2 24.3 27.5 49.8 10.0 29.4 12.7 25.5 38.2 22.1 21.1 21.5 30.2 37.9 29.3 9.2 16.0 10.7 32.0 22.8 34.7 21.7 42.0 36.6 27.3 21.0 49.2 38.8 7.2 34.3 17.1 30.2 60.6 32.7 45.0 43.7 51.7 70.8 42.9 38.3 45.6 34.7 50.4 40.2 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230175 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 35.8;NTERA-2: 17.8;TIME: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 2.2" "Lineage enhanced" "Detected in single" "granulocytes: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" 7750000 8300000 "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: " "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favourable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favourable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 28.6 7.8 8.1 4.6 5.9 0.4 17.9 3.4 5.4 10.8 4.7 4.6 3.4 3.2 14.5 5.3 6.7 5.9 9.1 13.0 7.1 6.1 25.4 8.7 27.8 2.9 6.9 3.4 6.1 4.5 3.5 4.0 36.3 6.9 5.4 4.7 12.4 3.4 5.5 7.8 3.0 5.3 10.6 5.3 23.4 4.0 3.7 3.5 0.3 9.7 8.4 2.4 6.4 12.4 0.0 0.1 2.2 0.6 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.2 2.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.0 0.0 0.6 0.0 0.0 0.7 0.0 0.8 0.3 35.8 0.0 0.0 0.3 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 38.8 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 8.1 5.9 3.4 5.4 7.1 6.1 6.9 3.4 6.9 3.5 TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295069 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease mutation, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 3.4;lymphoid tissue: 12.0;testis: 5.0" "Cell line enhanced" "Detected in some" "ASC TERT1: 61.2;fHDF/TERT166: 58.1;HBEC3-KT: 118.1;hTEC/SVTERT24-B: 74.6;LHCN-M2: 33.7;TIME: 96.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: , HPA065897: " "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" 0.0 0.0 0.0 7.1 0.9 3.4 0.0 0.0 0.2 0.1 1.1 0.0 0.0 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 2.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 1.0 0.4 5.0 0.0 12.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 30.6 61.2 0.5 0.0 23.3 4.2 7.9 0.1 0.1 0.7 0.0 58.1 0.0 0.2 118.1 5.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.2 0.0 3.0 74.6 0.8 0.2 0.6 0.1 33.7 0.0 0.2 1.6 0.4 0.2 0.8 0.0 0.8 3.4 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 96.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 TESK2 ENSG00000070759 "Testis-specific kinase 2" Q96S53 1 45343883-45491166 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 13.0;RT4: 12.7;SK-MEL-30: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA027257: AB_10602477, HPA063869: " "unprognostic (2.95e-1)" "prognostic favourable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" 5.5 3.3 6.1 5.9 17.4 12.6 9.6 7.8 12.6 7.7 8.4 25.7 4.0 11.9 4.7 5.7 9.1 4.1 3.9 5.8 9.6 5.1 3.5 9.7 5.5 6.0 19.2 4.7 14.4 4.6 6.7 4.1 8.3 13.2 22.1 10.1 7.6 11.2 5.7 10.1 17.1 14.8 4.4 18.7 6.3 5.6 11.7 14.8 4.2 5.1 3.2 7.2 8.2 9.7 7.5 2.0 15.9 5.9 1.1 3.7 2.6 1.6 0.0 0.8 0.0 3.2 1.7 13.0 0.6 4.3 1.9 3.2 3.6 1.5 5.2 0.6 1.5 2.0 3.4 2.7 1.5 3.7 4.3 3.5 1.8 2.7 1.7 1.2 9.8 1.8 2.9 2.1 3.0 1.5 0.6 10.9 1.2 0.6 3.0 2.4 3.4 1.5 4.4 0.1 1.4 1.7 12.7 0.3 1.4 3.3 6.4 12.1 9.9 1.5 0.0 0.2 2.0 1.6 1.1 7.1 4.2 1.0 1.0 0.0 0.8 9.4 3.8 10.6 2.4 2.8 1.7 7.5 2.2 1.6 2.0 5.7 3.7 2.1 15.9 1.1 5.9 1.1 1.5 2.6 6.1 17.4 7.8 12.6 9.6 5.1 19.2 4.7 13.2 14.8 TET1 "bA119F7.1, CXXC6, KIAA1676, LCX" ENSG00000138336 "Tet methylcytosine dioxygenase 1" Q8NFU7 10 68560656-68694482 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 15.1;HAP1: 17.2;K-562: 9.6;NTERA-2: 10.1" "Cancer enriched" "Detected in some" 15 "testis cancer: 10.4" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019032, HPA057273" Supported "Nucleoplasm,Nuclear membrane" Nucleoplasm "Nuclear membrane" "HPA019032: AB_1847363, HPA057273: " "unprognostic (1.60e-1)" "unprognostic (8.30e-2)" "unprognostic (9.85e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (8.15e-2)" "unprognostic (3.60e-3)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (7.90e-3)" "unprognostic (1.83e-1)" "unprognostic (1.71e-1)" "unprognostic (1.18e-3)" "unprognostic (2.88e-4)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (9.52e-3)" 4.4 1.6 3.3 4.3 2.6 1.6 3.1 4.4 4.3 5.1 2.4 5.8 3.2 1.2 6.0 3.4 2.4 2.9 3.5 2.4 3.5 2.3 1.8 1.5 1.6 1.7 2.5 2.6 6.1 1.6 7.4 2.2 5.8 2.9 3.2 2.0 8.1 15.9 4.8 4.0 2.2 1.8 6.5 3.6 1.7 2.2 1.4 5.9 1.2 3.2 3.2 1.8 5.1 5.4 1.3 1.1 1.0 0.0 0.9 2.3 0.2 0.6 0.7 6.8 7.7 0.7 0.6 15.1 0.3 0.8 0.6 1.1 4.6 0.2 0.0 0.2 0.7 0.0 17.2 0.0 0.7 0.2 2.7 1.8 0.0 4.0 1.0 1.5 0.9 0.9 0.1 0.4 0.0 0.1 9.6 1.2 0.6 0.5 2.7 1.2 10.1 0.9 2.6 2.2 0.2 0.3 0.7 1.9 3.0 0.3 0.4 1.4 0.9 1.2 0.2 0.6 1.4 0.0 0.5 0.5 0.5 2.7 0.1 0.0 0.1 0.0 0.0 1.0 1.5 0.0 2.0 1.3 0.8 1.3 0.2 0.5 1.4 1.1 0.0 0.9 0.0 1.1 2.3 0.2 3.3 2.6 4.4 2.6 3.5 2.3 2.5 2.6 2.9 5.9 TET2 "FLJ20032, KIAA1546" ENSG00000168769 "Tet methylcytosine dioxygenase 2" Q6N021 4 105145875-105279816 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 29.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043135 Supported Approved Nucleoplasm Nucleoplasm "HPA043135: AB_10794177" "unprognostic (6.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.69e-2)" "unprognostic (9.42e-2)" "unprognostic (4.15e-2)" "unprognostic (5.88e-2)" "unprognostic (6.12e-2)" "unprognostic (1.19e-3)" "unprognostic (1.15e-2)" "unprognostic (1.57e-2)" "unprognostic (5.77e-2)" "unprognostic (7.29e-2)" "unprognostic (2.70e-3)" "unprognostic (6.10e-2)" "unprognostic (1.89e-1)" "unprognostic (9.15e-2)" "unprognostic (7.84e-2)" 9.9 6.1 8.7 11.9 11.4 26.3 8.0 4.1 10.0 9.6 7.4 10.1 5.8 8.2 10.1 7.4 16.2 9.2 6.6 6.8 9.0 4.2 6.7 5.5 9.9 9.8 13.7 5.7 8.5 7.0 7.4 29.0 12.4 9.1 6.5 8.0 4.7 13.5 8.2 9.8 16.0 10.2 7.8 15.5 12.9 6.8 3.2 14.6 9.3 7.2 6.9 8.7 9.8 12.3 2.8 5.1 29.0 7.0 2.6 2.1 1.4 4.7 3.1 10.4 10.6 1.9 4.3 4.3 3.4 4.6 4.9 4.8 3.1 6.4 0.5 3.9 4.3 4.6 10.1 6.0 5.6 6.2 2.7 6.6 5.9 1.1 5.3 15.1 11.1 3.6 8.1 4.7 6.1 6.5 7.1 12.5 4.2 3.6 2.5 4.1 2.3 1.9 7.8 5.2 0.9 4.5 10.0 7.4 6.1 3.8 9.8 0.6 4.4 10.9 8.4 7.5 6.8 2.1 5.8 8.4 6.0 6.3 4.6 3.7 7.3 10.8 7.0 7.2 2.1 5.5 0.8 2.6 1.2 1.2 5.1 2.8 1.0 1.6 29.0 2.6 6.4 4.5 1.5 1.4 8.7 11.4 4.1 10.0 9.0 4.2 13.7 5.7 9.1 14.6 TET3 "hCG_40738, MGC22014" ENSG00000187605 "Tet methylcytosine dioxygenase 3" O43151 2 73986404-74108176 "Enzymes, Predicted intracellular proteins" "Chromatin regulator, Developmental protein, Dioxygenase, DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050845 Uncertain Approved Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "HPA050845: " "unprognostic (1.07e-2)" "unprognostic (1.21e-2)" "unprognostic (3.08e-1)" "unprognostic (1.12e-2)" "unprognostic (4.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.72e-3)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (9.83e-2)" "unprognostic (7.74e-2)" "unprognostic (2.03e-1)" "prognostic unfavourable (3.58e-5)" "unprognostic (2.05e-1)" "unprognostic (5.30e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-1)" 2.9 2.3 7.2 6.1 10.8 20.9 3.9 26.0 17.1 3.2 5.1 20.6 0.5 6.7 2.9 1.9 10.2 3.0 3.3 1.6 7.1 3.3 2.6 5.1 5.6 4.3 12.0 9.5 2.9 3.6 3.5 4.2 5.7 12.4 3.6 5.5 5.9 5.9 1.8 1.8 18.9 7.2 2.7 5.3 5.5 5.3 2.1 11.7 0.6 3.4 1.7 5.1 4.0 5.0 1.1 1.4 2.5 2.2 0.4 0.9 0.9 6.1 5.4 10.4 6.3 0.9 1.0 19.1 1.3 1.7 2.5 1.9 11.6 5.8 10.3 2.5 1.7 6.6 9.2 3.6 2.6 4.4 3.6 13.2 4.5 3.9 3.8 13.8 8.2 1.5 9.7 3.0 7.2 3.7 9.0 3.4 1.4 10.2 6.8 9.0 5.8 1.9 10.3 6.5 3.6 2.7 11.5 13.0 11.1 2.8 7.4 3.5 4.7 11.2 4.7 2.6 11.2 1.2 4.6 3.0 1.3 9.0 1.7 9.7 3.4 0.5 2.0 1.0 0.4 2.2 0.9 1.1 0.5 0.5 1.4 0.9 0.7 0.6 2.5 0.4 0.7 1.4 0.0 0.9 7.2 10.8 26.0 17.1 7.1 3.3 12.0 9.5 12.4 11.7 TEX14 CT113 ENSG00000121101 "Testis expressed 14, intercellular bridge forming factor" Q8IWB6 17 58556678-58692055 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "testis: 52.7" "Cell line enhanced" "Detected in some" "HDLM-2: 8.9;Karpas-707: 11.6;MCF7: 4.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030620, HPA077020" Enhanced Approved "Vesicles,Plasma membrane,Cell Junctions,Cytosol" "Plasma membrane, Cytosol" "Vesicles, Cell Junctions" "HPA030620: AB_10601598, HPA077020: " "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-1)" "unprognostic (9.49e-2)" "unprognostic (2.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.61e-3)" "unprognostic (2.67e-2)" "unprognostic (8.10e-2)" "unprognostic (1.76e-9)" "unprognostic (1.77e-1)" "unprognostic (2.54e-1)" "unprognostic (5.00e-3)" "unprognostic (5.88e-2)" 0.1 0.1 0.2 0.1 0.3 1.5 0.1 0.9 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.2 0.1 0.1 0.3 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.1 0.4 0.2 0.0 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.5 0.2 0.0 52.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.8 0.2 0.1 0.0 0.2 2.5 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.7 0.2 0.0 0.0 0.3 0.0 0.2 8.9 1.3 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.0 0.0 0.1 11.6 0.0 4.7 0.4 0.1 0.6 0.1 0.5 0.4 1.7 0.0 0.1 1.4 0.2 0.0 0.0 0.6 0.4 0.1 0.0 0.1 0.3 0.0 0.0 2.0 0.5 1.1 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.8 0.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.9 0.2 0.3 0.2 0.2 0.1 0.4 0.1 TFR2 "HFE3, TFRC2" ENSG00000106327 "Transferrin receptor 2" Q9UP52 7 100620416-100642779 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Receptor "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 112.6" "Group enriched" "Detected in some" 11 "HEL: 27.8;HMC-1: 38.6;K-562: 25.7" "Cancer enriched" "Detected in many" 70 "liver cancer: 136.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 46 "basophil: 5.5;eosinophil: 3.9" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011937, CAB016255" Enhanced "CAB016255: AB_628395, HPA011937: AB_1858243" "unprognostic (4.18e-2)" "unprognostic (1.97e-2)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (1.26e-2)" "unprognostic (4.13e-2)" "prognostic favourable (2.48e-4)" "unprognostic (2.29e-2)" "unprognostic (4.49e-2)" "unprognostic (9.26e-2)" "unprognostic (1.93e-1)" "unprognostic (2.90e-1)" "unprognostic (1.18e-9)" "unprognostic (6.51e-2)" "unprognostic (1.68e-1)" "unprognostic (3.28e-1)" "unprognostic (8.18e-2)" 0.1 0.0 0.1 0.1 0.1 5.3 0.1 0.8 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.0 0.1 112.6 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 2.8 0.0 0.6 38.6 0.0 0.0 0.0 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.1 0.1 0.0 0.1 0.1 0.1 0.1 TFRC "CD71, p90, TFR1" ENSG00000072274 "Transferrin receptor" P02786 3 196027183-196082189 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 110.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000153, HPA028598" Enhanced Supported Endosomes,Lysosomes "Secreted to blood" 1310000000 14000000 "Endosomes, Lysosomes" "CAB000153: AB_2533029, HPA028598: AB_10601599" "unprognostic (2.95e-2)" "prognostic unfavourable (3.67e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" "unprognostic (6.75e-2)" "unprognostic (7.88e-3)" "prognostic unfavourable (1.15e-4)" "unprognostic (6.92e-2)" "unprognostic (3.30e-3)" "unprognostic (4.35e-2)" "unprognostic (1.34e-2)" "unprognostic (1.14e-2)" "unprognostic (3.63e-3)" "unprognostic (3.65e-2)" "unprognostic (1.19e-2)" "prognostic unfavourable (2.96e-4)" "unprognostic (2.62e-2)" 24.3 11.9 11.9 20.6 11.3 73.8 7.6 9.6 17.8 11.8 25.0 9.5 3.8 11.9 12.1 7.5 18.5 11.7 11.4 18.7 9.5 8.3 15.3 13.6 28.1 8.1 7.4 9.5 50.0 7.8 18.0 6.9 110.0 26.5 7.2 19.4 8.5 8.3 5.0 25.6 9.9 37.4 10.9 13.2 7.9 10.0 8.3 6.1 14.3 7.0 10.5 12.9 11.2 8.0 5.7 7.5 2.2 12.4 1.8 6.5 2.1 21.9 20.0 9.2 18.6 20.4 11.8 57.5 31.4 23.9 22.1 36.7 48.7 20.2 22.5 59.6 11.6 33.9 31.5 10.4 27.1 107.6 10.7 85.3 17.0 22.6 16.1 69.9 17.3 13.3 10.3 19.0 17.2 7.3 35.5 21.6 17.2 20.3 22.9 14.8 28.0 41.0 12.2 13.7 27.0 19.8 55.6 21.0 8.7 30.3 79.7 7.1 77.4 14.6 9.4 26.3 21.4 23.0 47.0 6.1 47.5 35.2 30.8 19.0 15.9 0.0 1.6 2.2 2.5 7.9 1.7 5.7 2.7 1.7 3.7 3.2 2.5 1.9 0.3 1.8 12.4 7.5 6.5 2.1 11.9 11.3 9.6 17.8 9.5 8.3 7.4 9.5 26.5 6.1 TGDS "SDR2E1, TDPGD" ENSG00000088451 "TDP-glucose 4,6-dehydratase" O95455 13 94574051-94596257 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039927, HPA040857" Approved Approved Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "HPA039927: AB_10795238, HPA040857: AB_10794867" "unprognostic (4.07e-2)" "unprognostic (3.56e-1)" "unprognostic (2.66e-2)" "unprognostic (2.76e-1)" "unprognostic (1.27e-1)" "unprognostic (2.25e-2)" "unprognostic (1.60e-1)" "unprognostic (2.87e-1)" "unprognostic (9.99e-2)" "unprognostic (1.96e-1)" "unprognostic (9.17e-2)" "prognostic unfavourable (2.48e-4)" "unprognostic (5.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-2)" "unprognostic (1.09e-1)" 11.1 12.2 7.9 11.4 11.8 5.8 13.4 8.0 7.8 11.9 9.0 9.0 13.4 11.1 13.7 13.2 10.3 10.5 8.7 7.7 7.0 7.0 11.8 31.9 7.8 12.5 11.8 6.8 13.9 14.1 6.2 24.3 10.8 10.1 10.5 10.6 15.4 12.5 12.7 7.6 7.9 11.1 10.3 12.6 11.9 9.8 7.2 12.6 27.1 15.8 8.9 12.5 10.9 9.2 9.9 8.0 10.5 7.0 10.4 17.4 6.7 7.2 3.0 5.1 4.6 7.6 6.1 6.4 6.6 6.4 6.3 6.1 8.4 7.1 11.2 6.7 4.6 4.6 9.0 5.2 6.5 8.9 3.6 9.0 3.6 7.8 9.6 30.8 6.2 7.1 4.2 3.5 10.1 5.8 8.8 3.9 5.6 4.4 8.4 15.9 6.7 3.9 7.2 5.2 6.6 7.9 3.2 7.3 4.0 5.0 10.5 18.6 4.7 16.7 5.3 2.5 6.6 3.9 5.5 8.9 4.8 41.2 6.9 11.4 6.8 10.5 5.3 9.6 9.6 6.2 14.5 9.9 11.3 10.5 8.0 7.3 17.4 12.4 1.5 10.4 7.0 7.1 12.5 6.7 7.9 11.8 8.0 7.8 7.0 7.0 11.8 6.8 10.1 12.6 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: " "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 11.1 6.9 10.3 11.5 14.6 20.0 15.4 12.6 11.3 14.4 20.0 11.0 5.5 7.4 18.8 8.0 13.2 10.9 14.9 9.7 7.8 7.5 16.0 9.8 19.2 18.9 15.8 4.3 13.3 8.8 6.5 13.5 50.9 14.1 12.3 9.2 10.4 10.2 12.2 8.4 6.6 11.0 28.6 17.9 13.9 25.5 11.4 12.4 10.8 7.7 8.1 11.5 13.0 10.2 1.6 2.0 13.1 2.4 4.0 8.3 1.9 3.3 5.0 30.8 9.5 7.2 5.3 4.6 11.5 12.6 10.7 12.1 5.1 2.4 7.5 3.6 9.0 8.0 10.4 8.9 14.6 19.5 3.2 11.2 5.6 4.5 11.9 6.9 27.3 11.0 9.6 16.8 7.9 1.9 15.5 3.2 14.7 5.2 1.0 7.8 6.5 3.0 2.8 67.2 3.2 2.6 0.8 8.3 9.7 8.9 39.9 11.9 7.4 9.4 3.5 8.0 6.9 34.3 7.0 3.2 3.2 5.1 16.8 11.9 6.9 13.1 2.4 9.1 8.3 1.6 7.2 1.6 3.6 6.1 2.0 1.3 3.5 6.7 4.9 4.0 1.9 1.4 2.2 1.9 10.3 14.6 12.6 11.3 7.8 7.5 15.8 4.3 14.1 12.4 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606502-30694142 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 53.4;ASC TERT1: 80.5;HSkMC: 69.5;LHCN-M2: 65.8;TIME: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" 560000 "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 91.8 24.6 6.7 24.6 10.3 7.3 88.3 3.6 7.3 36.5 42.6 9.8 18.6 13.2 42.6 23.3 36.2 28.4 42.6 73.5 6.9 5.2 32.6 21.9 52.6 75.7 12.6 3.7 22.2 26.0 17.4 10.3 24.2 9.9 35.2 17.5 27.9 22.5 19.5 34.9 17.0 31.3 37.2 12.0 68.7 26.8 15.4 8.2 19.3 40.9 16.8 26.9 48.0 82.0 5.3 6.8 20.0 6.6 1.4 19.7 3.9 2.4 14.4 0.9 0.0 53.4 80.5 2.4 12.5 17.6 4.3 4.3 3.2 13.3 0.3 45.3 16.8 5.0 0.6 18.3 7.2 1.0 1.3 1.4 1.6 16.2 22.8 2.2 11.8 69.5 16.3 18.6 18.0 46.7 0.2 0.0 65.8 0.2 2.3 1.6 0.4 5.8 2.0 5.8 0.3 23.2 5.8 0.0 0.9 3.7 1.0 3.5 0.0 2.4 60.3 21.2 5.2 9.6 4.7 0.4 0.0 2.0 12.7 2.5 8.5 6.9 2.9 20.0 3.5 3.0 3.2 4.0 5.4 4.2 2.6 5.3 19.7 9.1 12.6 1.4 6.6 6.8 1.2 3.9 6.7 10.3 3.6 7.3 6.9 5.2 12.6 3.7 9.9 8.2 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 106.0;lymphoid tissue: 70.0;tongue: 86.8" "Cell line enhanced" "Detected in many" "BEWO: 12.8;HaCaT: 17.6;HeLa: 11.5;MCF7: 12.6;SK-BR-3: 15.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 78.3" "Region enriched" "Detected in single" 11 "cerebellum: 3.0" "Cell type enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171" Enhanced 430000 "CAB015159: AB_2202870, HPA040171: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 2.9 0.2 0.2 0.4 0.2 0.2 0.7 3.0 0.3 10.1 1.0 0.2 0.2 0.3 0.5 2.0 106.0 1.3 0.2 0.6 0.2 0.0 0.6 0.3 0.9 0.4 0.2 0.2 0.7 1.3 0.2 0.2 0.9 0.2 0.5 0.3 0.4 12.8 1.4 0.7 9.3 0.3 0.2 0.2 0.4 0.2 0.4 0.2 0.5 0.4 86.8 70.0 0.4 17.2 0.4 0.5 0.0 0.5 0.0 1.1 0.2 0.8 1.5 0.8 0.7 0.0 0.6 12.8 0.3 0.2 0.7 1.2 0.9 1.3 0.7 1.7 0.9 17.6 2.1 1.4 0.5 1.4 2.4 1.0 11.5 4.0 0.6 0.6 1.1 1.1 7.0 0.4 1.5 0.5 0.7 0.7 0.5 12.6 0.5 1.3 0.2 1.6 0.8 0.1 0.8 0.5 1.5 0.9 1.1 0.2 15.7 0.0 1.1 0.8 0.6 0.8 3.7 1.5 0.6 1.1 1.2 0.2 0.3 1.5 0.9 0.0 0.5 0.0 0.5 0.0 0.0 0.0 1.1 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.2 0.2 3.0 0.2 0.2 0.0 0.2 0.2 0.2 0.2 TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127387-38166578 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 187.6;placenta: 212.7" "Group enriched" "Detected in many" 4 "CAPAN-2: 160.1;EFO-21: 53.8;HUVEC TERT2: 72.7;TIME: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "intermediate monocyte: 2.5;memory B-cell: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 23 "B-cells: 1.9;dendritic cells: 2.4;monocytes: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" 1700000 Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavourable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavourable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" 33.3 9.5 6.0 18.3 8.1 1.0 7.7 4.3 7.5 94.3 12.6 4.0 4.7 8.4 54.6 21.7 15.8 58.7 62.8 77.1 7.5 3.4 25.3 187.6 61.2 16.4 6.9 3.0 18.7 5.0 5.2 25.6 212.7 8.5 33.6 6.3 57.4 1.9 17.1 19.3 0.7 12.8 43.9 5.7 20.4 13.6 7.4 6.4 0.8 17.0 3.4 3.1 38.2 21.6 1.9 2.4 0.0 2.5 0.0 0.0 0.2 6.5 4.9 0.0 0.1 5.1 0.5 2.5 9.9 4.8 0.0 0.1 8.0 160.1 0.0 53.8 0.1 0.1 0.0 23.2 0.3 0.0 0.0 1.0 0.2 3.5 20.9 0.0 0.0 0.5 0.0 4.2 0.0 72.7 2.1 0.0 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 7.2 0.0 0.0 0.1 23.2 0.0 0.8 0.2 0.0 94.8 0.1 6.0 0.7 4.7 0.0 0.0 0.0 6.5 0.0 1.9 0.0 0.2 0.0 0.0 2.5 0.0 1.9 0.0 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.0 8.1 4.3 7.5 7.5 3.4 6.9 3.0 8.5 6.4 TGM3 TGE ENSG00000125780 "Transglutaminase 3" Q08188 20 2296001-2341078 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 195.0;lymphoid tissue: 152.6;tongue: 206.5" "Cell line enriched" "Detected in some" 6 "EFO-21: 11.6" "Cancer enriched" "Detected in many" 9 "head and neck cancer: 81.6" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 205 "neutrophil: 20.4" "Lineage enriched" "Detected in single" 205 "granulocytes: 20.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA004728 Enhanced 14000000 "HPA004728: AB_1080360" "unprognostic (7.14e-2)" "unprognostic (8.93e-2)" "unprognostic (2.18e-2)" "unprognostic (3.23e-3)" "unprognostic (4.27e-2)" "unprognostic (4.20e-2)" "unprognostic (8.62e-2)" "unprognostic (4.21e-2)" "unprognostic (1.50e-1)" "unprognostic (8.00e-2)" "unprognostic (4.88e-3)" "unprognostic (1.35e-1)" "unprognostic (7.78e-8)" "unprognostic (1.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (9.67e-2)" 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.1 0.1 195.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 24.5 0.0 0.1 7.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 206.5 152.6 0.0 2.8 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TGM4 TGP ENSG00000163810 "Transglutaminase 4" P49221 3 44874608-44914990 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "prostate: 107.8" "Cell line enhanced" "Detected in some" "BEWO: 9.5;hTERT-HME1: 2.6;NB-4: 5.1;RPMI-8226: 3.6;SH-SY5Y: 2.8" "Cancer enriched" "Detected in single" 312 "prostate cancer: 75.4" "Region enriched" "Detected in single" 254 "cerebral cortex: 25.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA032072, CAB033571" Enhanced "CAB033571: AB_2287329, HPA032072: AB_10603350" "unprognostic (4.40e-2)" "unprognostic (4.68e-2)" "unprognostic (1.92e-1)" "unprognostic (2.17e-3)" "unprognostic (2.84e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (2.41e-2)" "unprognostic (1.65e-1)" "unprognostic (8.56e-3)" "unprognostic (5.08e-2)" "unprognostic (1.44e-8)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (3.68e-1)" "unprognostic (6.41e-2)" 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 25.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.6 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.1 2.6 0.3 0.0 0.0 0.1 0.0 0.0 5.1 0.0 0.2 0.0 0.0 3.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 1.4 0.5 0.0 0.7 0.7 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.0 TGM6 "dJ734P14.3, SCA35, TGM3L, TGY" ENSG00000166948 "Transglutaminase 6" O95932 20 2380908-2432753 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "lymphoid tissue: 5.7;skin 1: 3.3;tongue: 4.2" "Cell line enriched" "Detected in single" 12 "SCLC-21H: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 34 "cerebellum: 1.8" HPA059196 Uncertain "HPA059196: " "unprognostic (1.18e-1)" "unprognostic (2.84e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.2 5.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TH DYT5b ENSG00000180176 "Tyrosine hydroxylase" P07101 11 2163929-2171877 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Catecholamine biosynthesis, Neurotransmitter biosynthesis" "Monooxygenase, Oxidoreductase" "Disease mutation, Dystonia, FDA approved drug targets, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 31 "adrenal gland: 83.5;brain: 41.4" "Group enriched" "Detected in some" 32 "PC-3: 35.1;SK-BR-3: 12.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 4.0" "Group enriched" "Detected in many" 6 "hypothalamus: 15.5;midbrain: 41.4;pons and medulla: 41.2" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory region: 220.1" "Region enriched" "Detected in many" 19 "midbrain: 692.0" "CAB002522, HPA013768, HPA014010, HPA061003, CAB072340" Enhanced Supported Approved Cytosol Cytosol "CAB002522: AB_564047, CAB072340: , HPA013768: , HPA014010: , HPA061003: " "unprognostic (1.31e-1)" "unprognostic (1.30e-1)" "unprognostic (9.08e-2)" "unprognostic (1.75e-4)" "unprognostic (8.82e-3)" "unprognostic (5.88e-2)" "unprognostic (1.93e-1)" "unprognostic (1.74e-3)" "unprognostic (3.83e-2)" "unprognostic (4.39e-4)" "unprognostic (4.97e-1)" "unprognostic (3.61e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-1)" "unprognostic (2.43e-1)" "unprognostic (2.70e-2)" "unprognostic (2.18e-2)" 1.3 83.5 0.0 0.3 5.4 0.2 0.2 0.0 0.7 1.8 0.2 6.2 0.0 0.2 0.3 0.3 0.2 0.3 0.4 0.2 0.3 15.5 0.2 0.2 0.2 0.2 41.4 0.0 0.3 0.3 0.2 0.2 0.9 41.2 0.6 0.2 0.3 0.2 2.0 0.2 0.5 0.4 0.2 0.0 0.3 0.2 0.3 1.5 0.0 0.2 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 35.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.7 0.3 15.5 41.4 0.0 41.2 1.5 THEM4 CTMP ENSG00000159445 "Thioesterase superfamily member 4" Q5T1C6 1 151873584-151909808 "Enzymes, Predicted intracellular proteins" "Apoptosis, Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028161 Approved "HPA028161: AB_10603454" "unprognostic (2.88e-2)" "unprognostic (1.93e-1)" "unprognostic (1.50e-1)" "unprognostic (1.04e-2)" "unprognostic (1.29e-1)" "unprognostic (7.89e-2)" "prognostic unfavourable (1.38e-4)" "unprognostic (3.15e-3)" "unprognostic (2.23e-2)" "unprognostic (1.07e-1)" "prognostic favourable (2.51e-4)" "unprognostic (1.17e-1)" "unprognostic (4.19e-2)" "unprognostic (3.02e-2)" "unprognostic (9.25e-2)" "unprognostic (1.91e-1)" "unprognostic (5.93e-3)" 8.3 15.3 8.4 9.8 11.7 4.9 12.2 19.8 13.2 6.6 8.0 11.3 22.4 8.5 10.3 18.0 6.1 8.5 7.2 9.8 8.7 11.9 19.9 13.4 8.9 15.7 10.8 6.4 9.2 15.9 10.9 21.0 6.3 11.1 8.0 11.6 14.9 9.2 23.1 18.3 6.7 8.1 7.9 10.0 9.2 9.6 10.2 11.8 3.1 11.3 6.4 13.6 11.3 8.3 3.0 5.0 1.8 1.6 6.2 18.6 2.8 3.7 4.3 1.0 3.4 3.7 2.9 3.3 3.1 3.7 4.2 3.5 4.7 3.2 10.0 4.9 4.5 3.9 2.9 9.8 4.2 10.4 2.0 13.6 5.9 5.4 3.5 15.6 4.4 5.8 4.4 4.5 4.5 7.1 17.0 7.7 6.1 6.3 0.0 4.2 17.8 7.5 0.0 0.7 2.6 5.0 3.7 4.6 8.2 2.1 4.0 30.0 10.2 6.5 6.2 0.4 3.7 2.8 1.3 12.5 16.1 6.4 6.4 8.6 20.0 1.5 0.6 1.8 6.1 1.6 9.1 3.0 12.7 6.0 2.0 1.5 12.3 8.7 0.4 6.2 0.5 5.0 18.6 2.8 8.4 11.7 19.8 13.2 8.7 11.9 10.8 6.4 11.1 11.8 THG1L "FLJ11601, FLJ20546, hTHG1, ICF45, IHG-1" ENSG00000113272 "TRNA-histidine guanylyltransferase 1 like" Q9NWX6 5 157731197-157741448 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035877, HPA035878" Approved "HPA035877: AB_10669979, HPA035878: AB_10672993" "unprognostic (4.30e-3)" "unprognostic (2.64e-1)" "unprognostic (3.99e-3)" "unprognostic (2.86e-2)" "unprognostic (1.74e-1)" "unprognostic (4.37e-2)" "unprognostic (5.74e-3)" "unprognostic (4.08e-2)" "unprognostic (1.72e-1)" "unprognostic (7.16e-2)" "unprognostic (1.34e-1)" "unprognostic (4.05e-1)" "prognostic unfavourable (3.93e-6)" "unprognostic (1.48e-1)" "unprognostic (1.47e-1)" "unprognostic (3.09e-1)" "unprognostic (1.69e-1)" 7.9 9.7 4.1 7.9 4.1 7.6 8.0 5.2 6.6 12.7 12.0 6.7 9.6 8.2 15.2 9.4 13.5 9.9 11.6 6.2 4.3 4.9 7.3 10.6 7.5 7.7 4.8 3.6 13.5 12.5 5.4 10.0 7.4 4.7 15.8 11.9 6.8 6.9 9.8 7.6 8.1 9.7 15.8 4.7 12.3 10.5 7.9 4.4 11.2 21.9 9.3 9.8 17.5 8.9 7.7 7.8 5.9 10.2 7.1 8.5 4.5 6.3 11.1 5.5 10.2 5.1 15.1 4.2 5.0 9.4 10.3 13.9 15.3 6.5 15.9 4.3 4.4 6.8 6.7 9.6 11.6 6.5 9.2 5.7 7.6 6.5 5.8 11.9 6.0 13.7 11.6 9.0 12.5 3.7 9.9 5.1 6.1 8.8 1.4 8.0 5.2 11.1 2.3 10.4 9.0 6.4 8.1 6.9 9.7 4.0 6.1 8.1 10.3 6.9 4.2 8.3 5.5 6.8 13.3 4.5 5.0 10.3 3.6 11.5 5.2 5.9 9.6 0.1 4.2 9.8 5.0 7.7 5.8 4.5 7.8 6.7 8.5 7.1 0.9 7.1 10.2 5.9 5.3 4.5 4.1 4.1 5.2 6.6 4.3 4.9 4.8 3.6 4.7 4.4 THOP1 ENSG00000172009 "Thimet oligopeptidase 1" P52888 19 2785460-2815807 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025497, HPA035262" Uncertain Supported Cytosol 1400000 Cytosol "CAB025497: , HPA035262: " "unprognostic (1.52e-2)" "unprognostic (1.73e-3)" "unprognostic (7.94e-2)" "prognostic favourable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" "unprognostic (1.19e-1)" "unprognostic (4.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-3)" "unprognostic (3.00e-2)" "unprognostic (1.39e-1)" "prognostic favourable (5.90e-4)" "unprognostic (1.27e-1)" "unprognostic (2.64e-1)" "unprognostic (5.37e-2)" 8.2 9.4 19.1 12.3 19.8 18.4 6.2 21.7 26.1 5.2 11.8 14.1 5.8 24.6 7.5 8.4 11.0 8.4 6.7 11.6 18.5 15.4 7.1 30.4 6.2 11.9 14.1 15.2 11.1 7.8 7.0 12.7 22.3 13.1 18.1 8.2 11.9 13.7 6.8 29.1 11.9 20.0 7.1 10.7 9.8 7.8 27.3 10.9 17.0 7.5 11.5 11.3 5.8 6.8 7.5 9.8 8.0 7.5 3.9 9.5 3.2 29.2 21.8 8.5 18.2 4.4 4.3 30.4 18.3 6.8 18.2 14.8 25.6 9.4 26.4 9.0 7.1 23.8 12.6 15.0 7.7 0.1 26.5 9.3 24.0 30.2 4.7 18.0 14.6 4.8 5.4 15.1 6.8 10.3 21.7 12.9 7.7 22.7 20.0 33.8 25.1 30.1 16.7 11.3 25.0 7.6 17.0 23.1 18.5 16.0 14.4 8.9 14.0 17.5 11.7 14.0 12.1 29.8 30.9 22.7 19.0 17.8 15.6 30.3 16.6 8.0 3.5 1.6 5.5 3.9 4.5 5.6 4.0 7.4 4.9 7.5 5.1 4.3 1.7 3.9 7.5 9.8 9.5 3.2 19.1 19.8 21.7 26.1 18.5 15.4 14.1 15.2 13.1 10.9 THTPA THTPASE ENSG00000259431 "Thiamine triphosphatase" Q9BU02 14 23555988-23560271 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028876 Approved Uncertain Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA028876: AB_10600731" "unprognostic (3.50e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (7.11e-2)" "unprognostic (2.25e-1)" "unprognostic (2.12e-1)" "unprognostic (4.13e-1)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.50e-1)" "prognostic favourable (1.70e-9)" "unprognostic (3.47e-2)" "unprognostic (2.32e-1)" "unprognostic (3.62e-2)" "unprognostic (5.40e-2)" 14.9 19.5 27.7 12.2 23.3 7.6 12.9 16.4 24.3 12.3 14.0 20.7 15.9 15.7 13.3 18.4 10.1 17.7 16.8 16.3 23.3 17.4 16.3 12.1 10.7 10.7 21.9 13.3 15.4 12.7 25.0 12.4 7.6 16.1 18.8 12.3 17.1 18.0 23.5 21.9 7.4 11.7 13.7 19.5 11.3 11.6 18.8 14.3 14.1 15.9 12.3 11.2 9.9 7.9 14.3 17.0 11.1 14.4 6.9 11.6 8.7 2.7 17.2 8.5 9.1 19.4 11.0 4.7 8.0 7.1 8.0 7.9 3.5 11.4 5.2 7.1 9.6 8.5 8.9 10.0 5.9 11.0 9.6 7.1 12.1 9.4 9.8 6.5 6.4 14.8 7.4 12.1 9.0 9.5 5.3 11.5 11.5 8.2 10.2 2.7 3.0 14.6 7.0 5.7 9.5 14.0 5.5 16.3 7.8 7.9 16.3 4.7 10.9 3.2 7.5 5.2 5.6 10.8 4.7 13.6 8.2 2.9 5.5 2.9 8.0 11.1 14.4 7.3 9.6 10.6 9.5 9.6 6.9 7.5 13.2 14.3 11.6 9.9 1.5 6.9 13.4 17.0 5.4 8.7 27.7 23.3 16.4 24.3 23.3 17.4 21.9 13.3 16.1 14.3 TIGAR C12orf5 ENSG00000078237 "TP53 induced glycolysis regulatory phosphatase" Q9NQ88 12 4307763-4354593 "Enzymes, Predicted intracellular proteins" "Apoptosis, Autophagy" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034010, HPA040354, HPA044111" Approved Supported Cytosol Cytosol "CAB034010: AB_1128227, HPA040354: , HPA044111: " "unprognostic (1.76e-1)" "unprognostic (6.33e-2)" "unprognostic (4.08e-1)" "unprognostic (2.60e-1)" "unprognostic (1.32e-1)" "unprognostic (2.35e-1)" "prognostic unfavourable (3.18e-4)" "unprognostic (5.41e-2)" "unprognostic (2.11e-1)" "unprognostic (9.37e-2)" "unprognostic (1.85e-1)" "unprognostic (5.21e-2)" "unprognostic (2.03e-2)" "unprognostic (2.02e-3)" "unprognostic (2.44e-1)" "unprognostic (3.31e-1)" "unprognostic (1.05e-1)" 14.3 14.3 8.3 12.3 10.8 10.5 7.1 3.7 17.8 6.3 10.4 10.1 6.4 6.7 7.5 7.3 10.3 5.7 8.5 9.8 9.5 7.9 7.7 11.0 10.4 12.3 13.5 7.9 6.0 5.2 9.0 14.4 14.6 12.2 7.5 13.5 8.4 8.2 9.5 13.6 6.2 8.7 12.5 12.3 14.9 8.5 8.4 8.3 8.9 6.0 6.6 12.6 13.9 8.9 3.7 14.0 4.7 15.5 3.2 5.7 3.6 5.7 9.2 7.5 8.6 7.0 6.9 39.3 9.9 8.4 7.6 10.3 11.1 5.9 6.3 1.4 6.8 7.2 7.9 16.9 9.5 8.3 5.8 0.2 6.1 9.1 15.0 3.5 1.3 12.3 20.4 8.8 16.0 15.3 0.7 4.8 15.2 8.4 3.1 1.8 16.0 2.8 4.5 12.1 2.3 7.4 11.6 0.3 4.5 9.3 4.7 12.2 1.5 3.1 13.2 10.2 13.2 8.0 5.5 4.1 4.0 10.9 7.2 2.4 8.1 0.5 8.2 0.7 3.6 14.4 3.4 3.7 2.8 3.9 14.0 2.9 1.9 3.2 4.7 3.2 15.5 5.5 5.7 3.6 8.3 10.8 3.7 17.8 9.5 7.9 13.5 7.9 12.2 8.3 TINAG ENSG00000137251 "Tubulointerstitial nephritis antigen" Q9UJW2 6 54307859-54390152 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "intestine: 27.2;kidney: 53.0" "Cell line enriched" "Detected in some" 34 "RPTEC TERT1: 45.1" "Cancer enhanced" "Detected in some" "renal cancer: 15.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035427, HPA073753" Approved "Secreted to extracellular matrix" 26000 "HPA035427: AB_10601822, HPA073753: " "unprognostic (7.62e-3)" "unprognostic (1.12e-2)" "prognostic unfavourable (2.05e-5)" "unprognostic (7.27e-2)" "unprognostic (5.99e-3)" "prognostic favourable (8.75e-5)" "unprognostic (7.10e-2)" 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.2 0.0 9.5 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.1 53.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.2 0.0 0.0 0.0 0.2 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.4 0.0 TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 128.4" "Cell line enhanced" "Detected in many" "BEWO: 57.5;CAPAN-2: 31.4;EFO-21: 72.5;HaCaT: 31.5;HBEC3-KT: 37.1;HUVEC TERT2: 30.7;TIME: 65.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 4.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA048695 Approved "Secreted to extracellular matrix" 170000 "HPA048695: " "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favourable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favourable (9.64e-4)" "unprognostic (3.43e-2)" 43.0 8.4 2.2 11.6 3.4 0.8 60.0 0.8 4.4 30.2 22.0 2.9 14.2 12.0 25.7 23.4 23.7 17.0 36.1 52.6 3.4 2.3 53.3 14.7 24.4 12.8 3.9 3.3 15.5 7.4 3.2 5.6 128.4 5.0 19.4 7.9 12.0 24.2 20.0 19.6 7.6 15.9 22.5 2.7 34.3 16.3 10.3 2.1 0.8 30.7 11.0 6.4 39.8 20.0 1.1 0.6 4.8 0.5 1.5 0.8 0.0 16.4 0.0 0.0 0.1 0.1 0.0 57.5 2.6 0.3 0.1 0.0 7.7 31.4 0.0 72.5 2.3 31.5 0.0 37.1 0.0 0.1 0.0 0.0 1.3 1.9 0.8 0.0 0.1 0.0 6.7 0.0 1.3 30.7 0.4 0.0 0.0 0.0 0.1 0.1 0.1 1.0 0.0 0.0 0.0 10.0 12.7 0.0 0.1 6.6 22.2 0.7 1.3 0.0 65.6 0.0 16.6 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.5 4.8 0.5 0.5 0.8 0.3 0.5 0.4 0.6 0.5 0.1 1.1 0.8 0.8 2.7 1.5 0.5 0.6 0.5 0.0 2.2 3.4 0.8 4.4 3.4 2.3 3.9 3.3 5.0 2.1 TIPARP "DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1" ENSG00000163659 "TCDD inducible poly(ADP-ribose) polymerase" Q7Z3E1 3 156673235-156706770 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "basophil: 24.1" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036796 Approved Microtubules Microtubules "HPA036796: AB_10672268" "prognostic favourable (2.00e-5)" "unprognostic (3.50e-1)" "unprognostic (7.62e-2)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (4.56e-2)" "unprognostic (9.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.43e-1)" "unprognostic (4.27e-3)" "unprognostic (2.01e-1)" "unprognostic (4.69e-2)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (4.90e-3)" 31.6 29.8 10.9 11.1 24.7 31.8 19.9 7.1 16.3 16.2 12.7 14.2 18.8 6.8 18.3 20.7 27.2 27.8 18.8 26.5 16.0 9.4 14.2 21.3 20.2 15.2 16.2 6.2 37.0 14.5 73.8 11.4 6.1 30.9 13.6 7.5 10.0 8.2 36.0 17.4 26.2 22.1 21.6 37.4 8.4 11.3 23.1 12.5 8.4 10.8 19.1 13.8 18.7 16.7 3.7 3.3 24.1 5.4 7.0 6.0 2.2 12.5 8.8 3.0 2.5 11.1 8.1 2.4 20.9 17.0 10.7 14.9 5.0 26.1 3.7 6.8 23.7 13.0 7.5 50.2 15.9 7.9 5.6 6.3 9.2 3.4 4.7 2.1 11.6 6.6 31.5 10.8 26.2 9.7 4.9 15.1 37.0 2.4 1.8 2.8 3.4 7.4 3.0 6.8 12.8 11.2 5.9 9.2 2.3 16.4 5.1 3.5 7.9 3.7 20.9 4.6 1.5 8.6 7.5 16.9 3.0 3.3 7.9 3.3 15.5 24.1 3.5 4.7 4.2 2.2 6.0 1.9 4.2 5.6 2.3 3.7 2.6 3.5 10.7 7.0 5.4 3.3 4.7 2.2 10.9 24.7 7.1 16.3 16.0 9.4 16.2 6.2 30.9 12.5 TK1 ENSG00000167900 "Thymidine kinase 1" P04183 17 78174075-78187233 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.8;lymphoid tissue: 41.8;tongue: 33.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-reg: 21.2" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB004683 Enhanced "CAB004683: AB_437067" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.14e-3)" "unprognostic (3.22e-1)" "unprognostic (1.94e-1)" "prognostic unfavourable (6.87e-4)" "prognostic unfavourable (3.03e-5)" "unprognostic (4.05e-2)" "unprognostic (3.18e-3)" "unprognostic (6.64e-3)" "unprognostic (2.76e-2)" "prognostic unfavourable (6.50e-11)" "unprognostic (5.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (4.94e-2)" 5.3 2.0 2.1 21.4 4.5 32.8 4.8 1.1 1.9 3.7 11.4 2.2 1.9 8.5 2.4 4.8 18.9 2.2 7.0 4.3 1.6 0.7 7.9 6.2 9.3 15.7 3.1 1.6 2.1 3.6 0.1 1.3 8.6 2.1 2.3 7.9 0.5 4.6 2.0 2.0 6.2 8.5 4.4 1.7 9.0 9.4 3.6 1.6 41.8 1.3 33.0 20.5 3.1 5.8 4.0 2.1 1.1 1.2 6.2 21.2 3.5 65.1 54.2 10.8 13.6 1.0 4.3 7.1 32.4 17.0 48.2 66.9 47.8 27.5 21.2 11.4 19.4 29.7 9.8 28.9 25.0 7.3 36.2 37.4 19.4 31.3 0.3 15.8 24.2 2.1 0.9 25.1 3.4 19.6 23.0 47.0 18.5 48.7 7.9 8.9 5.6 37.8 21.4 43.8 47.3 12.8 21.2 4.9 14.3 24.8 68.2 9.1 46.0 21.3 9.0 47.4 46.6 33.8 41.6 19.8 10.3 27.3 23.3 10.7 21.3 0.0 0.7 0.0 1.1 1.2 0.5 4.0 5.3 2.7 2.1 1.2 0.3 1.4 1.1 6.2 1.0 0.7 21.2 3.5 2.1 4.5 1.1 1.9 1.6 0.7 3.1 1.6 2.1 1.6 TK2 SCA31 ENSG00000166548 "Thymidine kinase 2, mitochondrial" O00142 16 66508003-66552544 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Disease mutation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041162 Uncertain "HPA041162: AB_10961178" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.27e-3)" "unprognostic (3.94e-1)" "unprognostic (2.93e-1)" "unprognostic (1.10e-1)" "unprognostic (4.83e-2)" "unprognostic (3.35e-2)" "unprognostic (3.45e-1)" "unprognostic (3.59e-2)" "unprognostic (2.85e-1)" "prognostic favourable (2.18e-6)" "unprognostic (3.05e-2)" "unprognostic (1.74e-1)" "unprognostic (2.71e-1)" "unprognostic (7.05e-2)" 34.0 25.4 18.5 9.0 18.9 6.2 25.5 13.1 22.4 19.8 10.9 17.2 18.5 9.5 15.2 29.0 11.0 17.4 18.3 15.2 19.2 15.5 20.9 27.8 16.5 11.5 18.2 18.5 23.7 21.6 50.2 18.0 12.9 27.9 14.9 11.5 13.7 18.1 18.8 20.8 10.0 10.5 17.0 28.2 17.4 12.0 29.4 15.5 6.5 23.4 9.0 8.7 15.5 18.6 1.4 12.6 10.3 15.6 4.4 4.3 3.3 4.7 9.4 5.1 5.3 28.1 23.1 0.3 8.2 10.0 6.6 7.7 2.8 10.5 0.1 9.1 25.6 4.1 2.5 6.8 4.3 3.1 2.3 0.8 6.0 5.2 20.0 1.3 3.6 17.2 6.5 7.6 10.5 9.8 2.8 11.1 15.5 1.6 2.5 6.2 2.5 5.6 2.8 9.2 10.9 20.3 4.0 1.9 3.3 24.8 2.5 10.7 3.8 6.8 10.4 12.8 6.6 10.3 3.0 12.5 5.2 5.6 15.4 2.5 7.5 4.7 15.6 10.3 4.3 13.3 3.3 0.9 2.9 3.0 12.6 1.4 1.4 2.3 8.2 4.4 9.8 5.2 2.8 3.3 18.5 18.9 13.1 22.4 19.2 15.5 18.2 18.5 27.9 15.5 TKFC "DAK, DKFZP586B1621, NET45" ENSG00000149476 "Triokinase and FMN cyclase" Q3LXA3 11 61333210-61353295 "Enzymes, Predicted intracellular proteins" "Kinase, Lyase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 90.2;liver: 42.8" "Cell line enhanced" "Detected in all" "Hep G2: 39.8;RPMI-8226: 42.0;T-47d: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039486, HPA048186" Enhanced Approved Nucleoplasm,Cytosol 4800000 "Nucleoplasm, Cytosol" "HPA039486: AB_10795402, HPA048186: AB_2680305" "unprognostic (4.00e-1)" "unprognostic (3.13e-1)" "unprognostic (7.42e-2)" "prognostic favourable (1.32e-5)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (3.02e-2)" "unprognostic (2.81e-3)" "unprognostic (1.49e-1)" "unprognostic (2.47e-1)" "unprognostic (1.51e-1)" "unprognostic (2.15e-1)" "prognostic favourable (8.38e-5)" "unprognostic (2.07e-2)" "unprognostic (8.96e-2)" "unprognostic (3.30e-1)" "unprognostic (4.02e-1)" 3.1 34.7 3.6 6.1 5.3 5.3 4.6 3.7 7.3 3.4 43.4 7.6 8.0 69.5 4.6 7.8 6.2 5.9 8.8 2.8 3.1 2.6 17.4 42.8 3.5 5.2 3.3 5.3 4.5 9.8 3.0 5.5 3.9 4.4 5.0 2.3 7.3 7.2 7.1 4.6 6.1 90.2 2.6 3.1 5.4 5.7 17.1 3.4 5.5 6.4 6.3 6.7 5.4 3.9 9.7 18.4 5.4 11.4 5.3 10.9 7.8 6.0 15.3 2.7 9.3 3.4 3.7 7.6 3.5 3.8 3.3 2.1 6.9 14.6 7.5 12.4 2.5 8.5 5.0 6.6 1.1 12.9 6.7 4.6 8.1 39.8 5.8 3.9 7.8 5.8 4.5 3.1 11.0 3.3 8.1 14.5 2.4 27.4 3.4 3.6 7.4 10.5 6.1 4.2 42.0 5.3 10.7 10.4 9.3 6.5 11.4 5.9 42.0 2.8 3.9 6.6 6.9 5.2 2.1 26.9 22.2 6.7 6.8 3.6 6.0 2.3 11.4 5.4 6.7 6.8 8.6 9.7 7.8 6.5 18.4 9.7 5.6 5.9 0.9 5.3 5.3 9.0 10.9 7.8 3.6 5.3 3.7 7.3 3.1 2.6 3.3 5.3 4.4 3.4 TKT ENSG00000163931 Transketolase P29401 3 53224707-53256052 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 216.3" "Cell line enhanced" "Detected in all" "A549: 161.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 63.0;eosinophil: 41.5;intermediate monocyte: 31.0;myeloid DC: 32.5;neutrophil: 60.1;non-classical monocyte: 35.5" "Group enriched" "Detected in all" 8 "dendritic cells: 32.5;granulocytes: 60.1;monocytes: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029480, HPA029481" Enhanced Enhanced Nucleoplasm 190000000 Nucleoplasm "HPA029480: AB_10599307, HPA029481: AB_10601895" "unprognostic (5.05e-2)" "unprognostic (3.34e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "prognostic unfavourable (7.21e-6)" "unprognostic (6.78e-2)" "unprognostic (1.70e-1)" "unprognostic (4.73e-2)" "unprognostic (3.06e-3)" "unprognostic (1.36e-2)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.07e-1)" "unprognostic (3.29e-1)" "unprognostic (9.90e-3)" 53.6 37.0 21.2 24.1 26.0 216.3 70.1 18.1 24.3 19.0 24.3 21.1 9.9 31.8 16.9 9.5 60.4 21.8 36.5 15.3 19.4 23.0 51.9 27.4 50.1 45.6 33.4 16.0 35.2 69.9 22.5 16.9 29.8 28.7 25.2 19.6 17.5 21.0 21.6 5.2 16.8 22.5 34.5 28.2 45.6 24.5 10.8 23.3 44.8 67.7 37.9 25.1 58.2 57.3 6.8 32.5 60.1 63.0 4.7 5.7 37.6 31.8 161.2 23.1 25.6 51.5 63.0 47.1 21.6 37.5 37.4 35.8 44.5 82.0 40.1 10.4 31.5 46.2 40.0 81.3 11.1 13.3 22.2 26.7 112.8 66.8 63.0 32.6 18.1 45.5 46.8 44.8 23.1 47.1 19.0 17.5 15.2 38.9 34.0 36.5 78.3 38.9 20.6 10.5 74.5 58.5 54.2 15.0 11.1 40.2 64.4 38.8 20.0 45.2 35.2 11.6 17.9 34.1 41.2 10.1 18.9 24.0 25.3 33.0 21.5 7.0 63.0 41.5 3.0 31.0 3.8 6.8 4.4 3.4 32.5 3.5 4.6 3.4 60.1 4.7 35.5 5.5 5.7 37.6 21.2 26.0 18.1 24.3 19.4 23.0 33.4 16.0 28.7 23.3 TKTL1 "TKR, TKT2" ENSG00000007350 "Transketolase like 1" P51854 X 154295671-154330350 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "blood: 28.6;testis: 103.6" "Cell line enriched" "Detected in single" 157 "THP-1: 100.4" "Cancer enriched" "Detected in many" 8 "testis cancer: 44.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "eosinophil: 28.6;gdT-cell: 12.0" "Group enriched" "Detected in many" 6 "granulocytes: 28.6;T-cells: 12.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA000505, CAB032191" Enhanced Supported Cytosol Cytosol "CAB032191: , HPA000505: AB_1858022" "unprognostic (2.69e-1)" "unprognostic (1.92e-1)" "unprognostic (1.98e-1)" "unprognostic (5.80e-3)" "unprognostic (2.43e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-2)" "unprognostic (1.00e-1)" "unprognostic (2.10e-2)" "unprognostic (1.61e-1)" "unprognostic (1.98e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.34e-2)" "unprognostic (3.90e-2)" "unprognostic (5.04e-2)" "unprognostic (2.38e-1)" 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 103.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 28.6 0.1 3.3 12.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 100.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.8 0.0 28.6 12.0 0.1 1.8 0.0 1.4 1.1 0.0 0.0 3.1 2.7 0.4 3.3 0.1 0.1 1.5 2.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 TLK1 "KIAA0137, PKU-BETA" ENSG00000198586 "Tousled like kinase 1" Q9UKI8 2 170990823-171231314 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016043 Approved Supported Nucleoplasm Nucleoplasm "HPA016043: AB_1858027" "unprognostic (2.13e-2)" "unprognostic (3.87e-1)" "unprognostic (7.36e-2)" "unprognostic (6.00e-3)" "unprognostic (2.00e-1)" "unprognostic (6.78e-2)" "unprognostic (2.47e-2)" "unprognostic (7.60e-2)" "unprognostic (1.61e-1)" "unprognostic (5.26e-2)" "unprognostic (2.57e-1)" "unprognostic (1.11e-1)" "unprognostic (6.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.55e-1)" "unprognostic (2.63e-1)" "unprognostic (1.53e-1)" 13.8 20.1 22.0 32.9 21.0 14.4 26.2 18.3 23.2 19.6 20.2 8.4 22.3 13.7 16.1 16.1 14.1 14.4 16.2 12.7 20.6 19.3 19.5 21.4 22.1 33.7 21.7 20.8 21.5 19.8 37.8 21.0 36.0 18.3 18.0 18.2 10.8 16.4 30.3 18.6 15.4 18.9 20.5 18.7 26.0 19.9 24.2 12.2 28.0 25.7 11.1 21.7 21.9 19.1 10.5 5.3 11.3 5.5 9.5 12.3 6.6 8.5 8.3 12.1 9.4 8.6 8.7 13.4 11.8 17.3 12.0 10.1 11.5 13.9 17.7 9.7 17.8 7.3 15.3 13.2 13.2 21.0 7.7 20.5 10.4 14.9 9.3 25.9 10.4 9.4 13.5 23.8 15.7 13.1 21.0 15.1 7.2 10.6 21.7 8.3 11.1 4.7 16.4 14.7 18.2 9.9 16.5 13.8 10.7 12.9 9.2 8.8 7.5 9.1 17.8 10.7 13.1 7.0 9.2 12.7 21.3 32.1 13.3 10.7 10.8 11.3 3.9 6.5 6.6 3.0 9.1 10.5 10.7 7.2 3.5 10.5 12.3 8.1 5.0 9.5 5.5 5.3 10.0 6.6 22.0 21.0 18.3 23.2 20.6 19.3 21.7 20.8 18.3 12.2 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873258-166103895 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6" "Group enriched" "Detected in some" 4 "HeLa: 8.5;Karpas-707: 13.3;PC-3: 4.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "cerebellum: 40.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 10 "cerebellum: 132.6" HPA060767 Approved Vesicles "Secreted to extracellular matrix" Vesicles "HPA060767: " "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 10.1 1.3 1.2 2.6 2.8 0.0 7.9 40.6 2.9 5.0 5.4 0.2 4.2 1.4 3.0 2.7 2.5 2.4 5.4 2.4 2.2 1.7 3.3 0.5 3.1 3.0 1.1 0.6 1.6 4.6 1.1 2.2 13.8 8.5 3.1 2.2 3.3 1.9 1.9 1.6 2.7 4.4 3.3 0.9 0.4 1.7 1.5 0.1 0.0 3.2 1.4 1.6 3.6 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.0 0.5 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.1 0.0 8.5 0.0 0.0 0.0 0.0 0.5 1.5 0.0 1.8 1.4 0.0 13.3 0.0 0.0 0.0 0.2 1.2 4.8 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.8 40.6 2.9 2.2 1.7 1.1 0.6 8.5 0.1 TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 78.1" "Cell line enhanced" "Detected in many" "MCF7: 21.6;RPTEC TERT1: 24.9;T-47d: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 22.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" "Endoplasmic reticulum" Vesicles "HPA030691: AB_10602480, HPA072704: " "unprognostic (1.62e-1)" "unprognostic (5.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (6.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "unprognostic (1.69e-1)" "prognostic favourable (8.49e-8)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.44e-2)" 27.7 78.1 6.9 2.2 12.5 2.0 10.0 5.6 21.7 4.7 3.1 22.4 5.1 4.8 1.5 11.0 11.5 6.4 8.5 28.2 7.4 6.6 8.3 38.6 5.1 1.7 10.3 9.6 13.5 22.6 11.8 6.2 2.2 13.2 19.8 2.3 5.4 28.5 3.3 3.3 17.9 2.8 1.3 7.3 1.9 8.8 5.3 8.8 1.9 7.4 13.6 10.4 2.6 6.1 7.4 22.6 1.8 1.0 7.3 7.6 3.0 2.6 3.5 8.3 12.0 3.3 0.2 5.3 0.6 1.3 1.0 1.1 8.6 12.2 5.3 9.4 0.4 4.3 3.7 5.8 0.7 5.0 1.8 3.3 1.0 17.3 6.8 1.3 3.6 1.5 1.8 4.8 0.6 0.9 1.9 4.1 0.3 21.6 2.2 5.7 4.5 4.0 7.1 0.4 12.4 24.9 3.8 9.5 10.6 0.4 9.1 2.1 48.4 3.5 0.6 0.1 1.2 1.2 0.8 9.4 5.9 3.0 0.8 2.0 0.3 0.5 1.0 1.8 5.5 0.8 4.3 7.1 3.5 4.5 0.9 7.4 7.6 5.5 0.7 7.3 0.5 22.6 3.1 3.0 6.9 12.5 5.6 21.7 7.4 6.6 10.3 9.6 13.2 8.8 TMEM2 ENSG00000135048 "Transmembrane protein 2" Q9UHN6 9 71683366-71816690 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 67.6" "Cell line enhanced" "Detected in many" "AF22: 37.7;BEWO: 35.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044889 Approved Supported "Vesicles,Plasma membrane" 130000 "Plasma membrane" Vesicles "HPA044889: AB_10962641" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (6.15e-3)" "unprognostic (1.21e-2)" "unprognostic (2.93e-2)" "unprognostic (3.53e-1)" "unprognostic (3.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" "prognostic unfavourable (1.31e-4)" "unprognostic (1.13e-2)" "unprognostic (2.33e-1)" "unprognostic (7.59e-2)" "unprognostic (1.16e-1)" 23.3 3.9 6.0 10.5 4.4 12.4 13.6 8.9 6.0 3.0 18.6 1.9 10.1 12.2 4.5 5.2 4.4 4.9 19.2 9.5 8.6 3.6 9.3 24.9 35.7 14.0 4.0 4.1 3.1 9.2 24.0 9.5 67.6 4.3 5.5 13.1 7.9 9.5 10.2 5.5 6.4 20.0 5.5 5.1 15.6 14.5 3.7 2.4 6.4 8.0 4.6 8.8 11.4 6.8 6.3 0.9 5.5 2.1 0.5 4.1 1.4 5.9 28.8 37.7 1.7 3.9 7.1 35.0 20.3 13.0 14.1 10.4 8.1 8.2 0.1 6.1 5.2 9.0 12.2 2.8 19.2 0.7 3.7 10.3 6.1 21.4 6.1 0.0 2.8 7.3 3.1 10.9 2.4 18.5 1.4 3.0 7.6 5.0 1.2 0.1 7.8 2.8 0.9 11.2 0.8 8.9 19.4 1.9 0.2 5.3 3.7 5.4 2.6 0.4 8.1 9.6 10.8 5.3 10.1 0.6 8.7 0.3 1.8 0.9 12.1 0.2 2.1 5.5 2.7 1.9 0.8 0.7 2.9 2.6 0.9 6.3 4.1 2.0 4.5 0.5 1.8 0.2 3.9 1.4 6.0 4.4 8.9 6.0 8.6 3.6 4.0 4.1 4.3 2.4 TMEM86B MGC30208 ENSG00000180089 "Transmembrane protein 86B" Q8N661 19 55226639-55229264 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 15.1" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "liver cancer: 10.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057689 Uncertain Uncertain Midbody,Centrosome Centrosome Midbody "HPA057689: " "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.76e-5)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (6.55e-2)" "prognostic favourable (3.13e-4)" "unprognostic (1.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.10e-1)" "prognostic favourable (9.97e-6)" "unprognostic (1.96e-2)" "unprognostic (6.63e-8)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (3.70e-1)" "unprognostic (3.19e-3)" 2.5 2.4 2.8 3.1 4.0 7.8 1.4 4.7 4.2 1.4 7.5 1.4 1.4 5.6 1.5 1.4 1.4 1.8 7.7 2.9 2.2 1.6 2.0 15.1 2.7 5.2 1.4 1.4 1.4 1.4 1.7 2.8 5.2 1.7 1.5 0.4 1.4 1.4 1.4 2.2 3.0 7.7 1.4 1.4 4.3 3.6 2.8 1.4 1.4 2.3 1.4 3.0 1.4 1.4 0.7 1.0 0.6 0.7 0.0 1.6 0.4 4.1 3.9 2.4 3.9 0.4 0.6 3.6 1.4 0.7 1.3 1.8 6.3 2.2 4.7 1.2 1.1 1.7 0.9 1.0 0.6 0.9 11.1 8.8 2.5 5.9 1.2 3.9 3.7 0.8 1.7 2.1 1.3 0.5 6.0 3.5 0.8 2.4 6.4 10.0 0.9 2.4 5.9 2.8 12.5 1.1 5.1 2.1 3.9 1.8 0.8 4.9 2.2 8.3 2.8 5.7 3.2 2.5 3.8 2.9 3.4 10.2 4.7 11.1 2.1 0.0 0.7 0.6 1.6 0.1 0.6 0.0 0.5 0.1 0.1 0.7 0.6 1.4 0.1 0.0 0.1 1.0 0.0 0.4 2.8 4.0 4.7 4.2 2.2 1.6 1.4 1.4 1.7 1.4 TMEM8A "M83, PGAP6, TMEM6, TMEM8" ENSG00000129925 "Transmembrane protein 8A" Q9HCN3 16 370773-387113 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 24.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051281, HPA064673" Approved Supported "Nucleoplasm,Cytokinetic bridge" Nucleoplasm "Cytokinetic bridge" "HPA051281: , HPA064673: " "unprognostic (5.84e-2)" "unprognostic (6.13e-2)" "unprognostic (3.85e-2)" "unprognostic (3.21e-2)" "unprognostic (5.77e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-3)" "unprognostic (1.56e-2)" "unprognostic (8.89e-2)" "unprognostic (7.73e-2)" "unprognostic (3.43e-1)" "unprognostic (1.38e-2)" "prognostic favourable (1.29e-5)" "unprognostic (4.20e-3)" "unprognostic (3.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.48e-1)" 8.4 9.3 6.9 9.5 7.8 15.2 13.5 7.7 7.9 6.8 16.6 7.3 24.1 17.7 7.3 29.6 11.8 6.5 15.2 10.0 5.6 4.3 28.7 33.5 13.0 10.7 7.1 3.2 8.3 44.2 11.5 10.7 45.5 6.7 11.4 6.0 8.8 22.5 8.8 12.8 3.7 25.0 5.0 4.7 13.2 17.5 26.3 6.0 12.6 12.3 5.2 14.6 9.3 8.8 2.0 2.9 24.3 5.5 0.9 7.6 3.3 4.4 11.7 6.7 12.3 9.2 8.3 13.4 12.7 13.3 6.5 9.3 45.8 20.8 4.7 17.3 12.2 6.3 3.0 14.0 1.8 13.4 11.2 7.8 7.9 26.1 21.3 5.9 14.8 9.6 4.2 10.0 2.9 15.0 12.5 7.3 8.1 27.4 8.2 11.5 10.6 4.6 17.9 7.7 10.8 10.5 11.4 8.0 9.2 7.1 7.2 37.4 12.9 11.8 21.8 18.5 20.0 12.8 6.7 14.7 7.3 9.3 9.4 6.3 11.7 4.6 5.0 6.3 7.4 5.5 5.9 1.8 5.8 5.8 2.5 2.0 7.6 5.5 24.3 0.9 3.8 2.9 4.3 3.3 6.9 7.8 7.7 7.9 5.6 4.3 7.1 3.2 6.7 6.0 TMLHE "BBOX2, FLJ10727, TMLH, XAP130" ENSG00000185973 "Trimethyllysine hydroxylase, epsilon" Q9NVH6 X 155490115-155669944 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Autism, Autism spectrum disorder, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034589, HPA040331" Approved Supported Mitochondria Mitochondria "HPA034589: AB_10670571, HPA040331: " "unprognostic (1.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.04e-1)" "unprognostic (5.41e-2)" "unprognostic (6.66e-3)" "unprognostic (1.10e-3)" "unprognostic (6.50e-2)" "unprognostic (1.00e-1)" "unprognostic (3.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.20e-3)" "unprognostic (6.97e-2)" "prognostic favourable (3.68e-6)" "unprognostic (1.69e-1)" "unprognostic (5.74e-2)" "unprognostic (2.73e-1)" "unprognostic (7.75e-2)" 10.1 15.0 8.5 6.7 10.5 6.7 10.4 17.1 13.5 11.3 10.5 10.0 9.1 10.7 10.9 10.1 9.5 9.5 7.4 22.3 10.3 7.5 15.8 16.9 6.9 14.6 12.5 7.4 12.4 10.7 18.4 17.5 7.6 11.5 7.7 11.6 10.6 16.2 9.6 28.1 7.8 10.0 13.8 13.7 9.2 9.8 3.1 11.2 12.2 10.5 5.3 8.7 10.2 9.1 9.1 10.3 14.7 15.7 4.3 5.6 4.5 15.2 7.5 6.2 18.1 7.7 11.9 0.0 6.2 9.1 7.8 20.4 5.3 8.6 0.0 25.0 10.8 8.3 13.2 6.0 8.9 6.2 9.1 6.8 12.2 6.2 10.8 6.4 4.9 12.6 12.7 8.7 13.2 12.3 9.5 5.6 12.9 5.7 7.7 7.2 1.9 0.1 7.7 9.9 5.8 9.4 5.2 5.9 8.9 5.8 0.3 6.7 6.7 7.3 10.3 6.6 6.3 13.0 7.6 7.0 7.5 5.9 8.0 10.0 6.0 1.9 10.1 11.3 3.9 11.4 2.9 6.2 4.3 3.3 10.3 9.1 5.6 4.9 14.7 4.3 15.7 4.7 4.2 4.5 8.5 10.5 17.1 13.5 10.3 7.5 12.5 7.4 11.5 11.2 TMPRSS11D ENSG00000153802 "Transmembrane serine protease 11D" O60235 4 67820876-67884032 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix, uterine: 18.1;esophagus: 41.2;lymphoid tissue: 20.3;tongue: 67.6;vagina: 23.1" "Cell line enhanced" "Detected in single" "RH-30: 1.2" "Group enriched" "Detected in many" 5 "cervical cancer: 36.0;head and neck cancer: 30.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052834 Uncertain "Intracellular and membrane" "HPA052834: " "unprognostic (1.19e-1)" "unprognostic (6.83e-2)" "unprognostic (8.82e-2)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (4.79e-1)" "unprognostic (4.38e-3)" "unprognostic (1.96e-1)" "unprognostic (6.91e-2)" "unprognostic (4.48e-2)" "unprognostic (2.19e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.0 0.6 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 67.6 20.3 0.4 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMPRSS11E "DESC1, TMPRSS11E2" ENSG00000087128 "Transmembrane serine protease 11E" Q9UL52 4 68447449-68497604 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.8;lymphoid tissue: 39.1;tongue: 40.5;vagina: 36.6" "Group enriched" "Detected in some" 6 "HaCaT: 5.8;HBEC3-KT: 2.2" "Group enriched" "Detected in many" 6 "cervical cancer: 22.0;head and neck cancer: 25.3;lung cancer: 11.5;urothelial cancer: 7.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "memory B-cell: 1.8" "Lineage enhanced" "Detected in single" "B-cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA051062 Enhanced "Intracellular and membrane" "HPA051062: " "unprognostic (2.53e-1)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" "unprognostic (9.14e-2)" "unprognostic (5.03e-2)" "prognostic unfavourable (6.73e-4)" "unprognostic (2.22e-1)" "unprognostic (9.70e-3)" "unprognostic (2.16e-1)" "unprognostic (3.74e-2)" "unprognostic (4.03e-2)" "unprognostic (8.39e-2)" "unprognostic (1.27e-1)" "unprognostic (3.08e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 28.9 0.0 0.0 1.2 0.0 1.1 10.5 103.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 1.4 0.0 0.0 13.6 0.5 0.0 1.6 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 40.5 39.1 2.6 36.6 1.8 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 5.8 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMPRSS11F FLJ16046 ENSG00000198092 "Transmembrane serine protease 11F" Q6ZWK6 4 68053198-68129880 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 18.3;lymphoid tissue: 11.4;skin 1: 10.9;tongue: 13.1" "Group enriched" "Detected in some" 8 "HEL: 2.4;K-562: 5.4;Karpas-707: 1.6;U-266/70: 1.6" "Group enriched" "Detected in some" 7 "cervical cancer: 1.6;head and neck cancer: 2.1;lung cancer: 0.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026911 Uncertain "HPA026911: AB_2205589" "unprognostic (9.46e-2)" "unprognostic (5.30e-1)" "unprognostic (7.16e-2)" "unprognostic (8.79e-3)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.2 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.1 0.0 0.0 1.4 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 13.1 11.4 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMPRSS15 "ENTK, MGC133046, PRSS7" ENSG00000154646 "Transmembrane serine protease 15" P98073 21 18269116-18485879 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 67 "intestine: 154.6" "Group enriched" "Detected in some" 20 "U-138 MG: 19.8;U-87 MG: 55.3" "Group enriched" "Detected in some" 12 "liver cancer: 0.7;pancreatic cancer: 1.5;stomach cancer: 1.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 2.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "olfactory region: 9.3" "HPA015611, HPA034857, HPA072934" Enhanced Approved "Nucleoli,Plasma membrane" "Plasma membrane" Nucleoli "HPA015611: AB_1855791, HPA034857: , HPA072934: " "unprognostic (9.26e-2)" "unprognostic (4.14e-1)" "unprognostic (3.52e-1)" "unprognostic (8.33e-2)" "unprognostic (1.19e-1)" "unprognostic (7.20e-2)" "unprognostic (4.70e-2)" "unprognostic (6.35e-2)" "unprognostic (5.92e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 80.5 0.0 0.0 154.6 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 42.4 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.5 0.1 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.1 0.0 0.3 0.0 0.0 55.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464551-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 75.6;pancreas: 64.5;prostate: 68.2" "Cell line enhanced" "Detected in some" "CACO-2: 14.6;MCF7: 6.3;RT4: 35.2;SK-BR-3: 7.2;T-47d: 5.4" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034493, HPA035787" Enhanced Supported "Nucleoplasm,Cell Junctions" "Intracellular and membrane" "Cell Junctions" Nucleoplasm "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favourable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favourable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.2 0.1 0.2 15.5 0.4 0.0 6.1 0.2 0.5 1.3 38.7 0.4 24.4 17.5 0.5 0.9 10.7 2.2 17.3 0.2 0.3 0.1 19.4 18.4 20.7 0.2 0.2 0.2 0.7 64.5 0.0 1.3 1.0 0.4 68.2 18.5 0.3 52.3 35.7 0.2 2.1 75.6 0.9 0.2 0.3 36.7 0.8 0.3 0.5 19.9 3.9 10.2 5.9 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 14.6 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.1 0.5 1.3 0.0 0.0 0.0 1.4 0.6 35.2 0.0 0.4 0.0 7.2 0.1 5.4 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.4 0.2 0.5 0.3 0.1 0.2 0.2 0.4 0.3 TMPRSS4 "MT-SP2, TMPRSS3" ENSG00000137648 "Transmembrane serine protease 4" Q9NRS4 11 118077012-118121890 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.9;gallbladder: 45.4;lymphoid tissue: 41.0;urinary bladder: 43.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 44.9;HaCaT: 19.2;RPTEC TERT1: 31.5;RT4: 39.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "basophil: 4.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006238 Uncertain Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006238: AB_1080316" "unprognostic (1.48e-1)" "unprognostic (3.27e-2)" "unprognostic (1.19e-2)" "unprognostic (1.23e-1)" "unprognostic (5.23e-2)" "unprognostic (5.50e-2)" "unprognostic (8.17e-3)" "unprognostic (1.95e-2)" "unprognostic (2.41e-1)" "unprognostic (9.62e-2)" "prognostic unfavourable (3.14e-4)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-2)" "unprognostic (9.96e-3)" 0.3 0.3 0.2 14.2 0.3 0.0 0.3 0.3 0.2 11.4 23.5 0.1 0.0 16.1 3.1 2.8 60.9 0.6 45.4 0.3 0.3 0.3 17.7 0.3 3.2 0.0 0.2 0.0 0.3 0.4 0.0 0.3 0.8 0.1 9.9 26.2 0.2 4.0 0.0 0.3 2.4 27.4 4.2 0.2 0.3 13.7 0.7 0.0 0.6 0.3 13.7 41.0 43.9 22.3 0.5 0.1 4.5 0.7 0.2 0.1 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 44.9 0.0 1.7 0.0 19.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.4 0.1 1.3 0.0 0.0 0.0 0.0 0.0 31.5 39.3 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.3 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.5 0.1 0.1 0.9 0.2 0.7 0.1 0.1 0.0 0.2 0.3 0.3 0.2 0.3 0.3 0.2 0.0 0.1 0.0 TMPRSS5 "MGC141886, MGC148044" ENSG00000166682 "Transmembrane serine protease 5" Q9H3S3 11 113687546-113706373 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 24.0;salivary gland: 15.0;skeletal muscle: 6.0" "Cell line enhanced" "Detected in some" "AF22: 4.4;CAPAN-2: 7.1;WM-115: 5.8" "Cancer enhanced" "Detected in some" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010992 Approved Nucleoplasm Nucleoplasm "HPA010992: AB_1858152" "unprognostic (1.53e-2)" "unprognostic (3.81e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (2.99e-3)" "unprognostic (3.08e-1)" "unprognostic (5.19e-3)" "unprognostic (8.49e-2)" "unprognostic (8.13e-2)" "unprognostic (3.38e-2)" "unprognostic (1.96e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (4.04e-3)" 2.1 1.7 10.8 1.0 24.0 3.2 2.2 2.1 14.8 1.2 1.0 21.6 0.0 1.0 1.2 0.9 1.8 1.1 2.2 1.2 11.5 5.7 0.9 0.9 0.9 1.1 11.6 12.7 1.4 1.2 0.6 1.5 1.2 16.5 1.2 1.3 0.9 15.0 1.4 6.0 2.7 0.7 1.2 16.9 1.1 2.4 2.3 8.8 0.0 1.1 0.4 1.3 0.9 0.4 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.8 4.4 2.5 0.5 0.4 0.6 1.2 0.5 0.6 0.9 2.5 7.1 0.3 3.2 0.5 0.8 0.4 0.4 0.3 0.5 1.3 1.0 0.6 0.0 0.3 1.0 0.8 0.6 0.6 0.6 1.2 0.8 0.8 0.5 0.9 0.0 0.8 1.2 0.5 0.2 0.9 0.5 0.0 0.7 0.4 0.6 1.0 0.5 0.1 3.5 0.5 0.6 0.5 0.9 1.7 0.6 0.7 0.5 0.2 0.1 0.4 0.9 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 24.0 2.1 12.3 11.5 5.7 11.6 12.7 16.5 8.8 TMPRSS7 ENSG00000176040 "Transmembrane serine protease 7" Q7RTY8 3 112034843-112081269 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 2.2;testis: 5.2" "Cell line enhanced" "Detected in some" "HaCaT: 1.4;hTCEpi: 2.7;RT4: 1.3;U-266/70: 1.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA040630 Uncertain "HPA040630: AB_10796124" "unprognostic (4.02e-2)" "unprognostic (9.87e-2)" "unprognostic (9.05e-2)" "unprognostic (2.16e-2)" "unprognostic (2.24e-1)" "unprognostic (4.64e-3)" "unprognostic (6.63e-2)" "unprognostic (2.16e-1)" "unprognostic (2.29e-2)" "unprognostic (4.64e-1)" "unprognostic (1.68e-1)" "unprognostic (1.94e-1)" "unprognostic (7.23e-2)" "unprognostic (2.96e-1)" "unprognostic (2.06e-2)" 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.2 0.0 0.1 0.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.0 0.2 0.1 0.1 0.0 0.5 0.8 0.0 0.0 0.0 1.0 5.2 0.3 0.0 0.2 0.0 0.8 0.5 2.2 0.3 0.5 0.7 0.1 0.3 0.0 0.7 0.2 0.4 0.1 0.9 0.6 0.7 0.2 0.5 0.6 0.2 0.0 0.0 0.0 1.4 0.0 0.9 0.6 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.8 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.1 0.4 0.0 0.8 0.0 0.5 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 2.2 0.3 0.7 0.2 0.2 0.1 0.6 0.3 0.2 0.0 0.8 0.7 0.2 1.7 0.5 0.2 0.5 0.2 0.1 TMPRSS9 ENSG00000178297 "Transmembrane serine protease 9" Q7Z410 19 2389771-2426239 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 6.3;lymphoid tissue: 4.6;testis: 5.9" "Cell line enhanced" "Detected in some" "Karpas-707: 6.1;SK-BR-3: 3.1;U-266/70: 5.4" "Low cancer specificity" "Detected in some" "Cell type enhanced" "Detected in single" "eosinophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Region enhanced" "Detected in single" "basal ganglia: 0.5" "Low region specificity" "Detected in all" HPA051483 Uncertain "HPA051483: " "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (5.62e-3)" "unprognostic (1.86e-1)" "unprognostic (1.54e-2)" "unprognostic (1.87e-3)" "unprognostic (3.30e-1)" "unprognostic (6.44e-2)" "unprognostic (7.29e-2)" "unprognostic (2.07e-1)" "unprognostic (6.30e-2)" "unprognostic (9.20e-3)" "unprognostic (2.28e-3)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (3.07e-3)" "unprognostic (6.73e-2)" 0.1 1.1 0.9 0.4 0.2 2.0 1.3 0.0 0.2 0.0 0.4 0.3 0.4 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 6.3 0.0 0.1 0.0 0.2 1.2 0.0 0.2 0.1 0.1 0.0 0.5 0.0 1.5 1.8 0.4 0.0 0.0 4.6 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.9 2.4 0.0 0.0 0.0 0.1 1.7 0.3 0.2 0.6 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.6 0.5 0.4 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.8 0.2 2.1 2.3 0.0 2.3 0.3 0.0 0.0 0.0 0.0 0.0 1.0 6.1 0.0 1.2 0.1 0.4 0.5 0.8 1.1 0.0 0.8 0.0 0.3 0.1 0.2 0.2 3.1 0.1 0.4 1.6 0.4 1.1 0.8 1.1 0.7 5.4 1.3 1.5 0.2 0.9 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715298 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavourable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" 22.8 16.8 14.7 22.8 31.3 12.2 20.5 28.0 34.2 16.4 15.4 14.0 16.0 17.8 22.1 21.7 16.9 18.3 16.8 20.2 17.1 18.2 19.2 19.9 23.3 25.6 14.2 18.7 16.0 16.3 20.4 19.3 19.6 26.8 18.7 16.9 18.2 14.6 16.3 14.1 16.5 21.1 21.1 16.7 26.3 15.2 11.1 11.1 29.6 19.2 13.4 22.1 19.9 14.8 4.9 9.6 3.4 6.9 7.6 8.7 4.1 3.3 5.4 10.6 8.2 21.9 23.4 7.8 26.9 28.7 19.6 21.9 2.5 10.0 9.7 5.3 39.1 12.9 6.9 13.5 30.2 9.2 6.2 8.9 8.6 4.5 23.2 18.8 14.7 18.6 8.7 21.2 19.2 24.8 5.7 13.5 23.2 2.1 10.1 6.0 4.4 8.9 9.4 20.9 11.8 16.6 7.4 10.2 7.9 13.1 8.5 9.9 5.5 16.1 23.7 35.1 9.6 7.8 19.6 9.1 9.1 9.1 21.2 15.6 25.6 2.6 4.3 3.4 6.1 6.9 8.7 4.9 6.3 5.6 6.9 3.6 7.1 6.9 1.1 7.6 4.7 9.6 6.4 4.1 14.7 31.3 28.0 34.2 17.1 18.2 14.2 18.7 26.8 11.1 TNFAIP3 "A20, OTUD7C" ENSG00000118503 "TNF alpha induced protein 3" P21580 6 137867188-137883312 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Inflammatory response, Ubl conjugation pathway" "DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 112.4" "Cell line enhanced" "Detected in many" "Karpas-707: 48.4;REH: 42.0;U-266/84: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002116, HPA067479" Approved Supported Vesicles Vesicles "HPA002116: AB_1858162, HPA067479: " "unprognostic (5.50e-3)" "unprognostic (9.98e-3)" "unprognostic (3.06e-2)" "unprognostic (1.01e-2)" "unprognostic (4.01e-2)" "unprognostic (9.47e-2)" "unprognostic (5.01e-3)" "unprognostic (4.40e-2)" "unprognostic (2.92e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "prognostic unfavourable (6.05e-4)" "unprognostic (6.06e-2)" "unprognostic (3.55e-3)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" 27.4 6.0 1.5 58.6 1.8 112.4 17.2 0.4 1.5 7.7 15.7 3.2 2.6 5.1 9.7 7.3 12.7 12.1 17.0 11.7 2.1 1.3 6.8 8.1 45.1 38.8 2.1 2.6 37.5 7.2 2.1 3.7 14.5 4.6 13.8 6.3 7.2 8.2 3.5 10.7 20.5 17.2 8.2 3.8 25.9 8.0 9.3 2.1 38.6 5.7 9.2 31.4 23.3 9.5 7.1 18.6 10.0 9.7 7.5 20.5 9.0 8.9 1.5 0.5 0.8 3.0 5.1 2.1 5.1 20.0 1.4 1.8 9.9 3.0 2.0 13.2 5.9 6.8 0.3 14.8 2.6 14.6 0.5 2.0 5.2 5.8 3.3 2.7 3.7 4.7 2.1 16.9 16.1 0.8 4.1 48.4 2.4 0.5 14.7 11.5 0.3 0.4 42.0 10.4 1.4 4.4 4.3 0.2 0.0 1.0 1.5 4.4 1.0 3.4 4.0 14.5 1.7 12.9 2.9 15.6 36.1 4.1 5.3 3.5 1.8 5.6 9.7 5.5 14.8 7.1 20.5 6.2 15.1 13.3 10.3 7.1 10.0 7.4 10.0 7.5 3.7 18.6 14.7 9.0 1.5 1.8 0.4 1.5 2.1 1.3 2.1 2.6 4.6 2.1 TNIK KIAA0551 ENSG00000154310 "TRAF2 and NCK interacting kinase" Q9UKE5 3 171061339-171460408 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.9" "Cell line enhanced" "Detected in many" "AF22: 19.6;HEL: 26.6;HMC-1: 30.3;HUVEC TERT2: 19.5;WM-115: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 23 "basophil: 4.4;eosinophil: 10.5;gdT-cell: 4.2;MAIT T-cell: 5.2;memory CD4 T-cell: 5.0;memory CD8 T-cell: 3.7;naive CD4 T-cell: 6.7;naive CD8 T-cell: 3.8;NK-cell: 2.7;T-reg: 5.3" "Group enriched" "Detected in many" 29 "granulocytes: 10.5;NK-cells: 2.7;T-cells: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012128, HPA012297" Approved Supported Nucleoplasm,Cytosol 9100 Nucleoplasm Cytosol "HPA012128: AB_1858226, HPA012297: AB_1858225" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (1.32e-1)" "unprognostic (5.90e-2)" "unprognostic (5.25e-2)" "unprognostic (9.23e-2)" "unprognostic (4.91e-2)" "unprognostic (2.41e-3)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (5.91e-2)" "unprognostic (1.96e-2)" "unprognostic (3.34e-3)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (2.13e-2)" "unprognostic (3.97e-2)" 2.2 5.4 29.0 7.4 30.9 4.9 3.6 21.1 26.1 1.9 10.9 12.2 4.1 25.8 4.3 2.1 5.6 4.3 7.1 11.2 30.9 14.8 5.6 4.6 11.3 7.9 11.4 18.3 2.6 5.2 0.7 9.0 3.1 13.6 5.6 9.5 3.5 2.9 7.3 23.2 1.6 25.6 6.0 14.5 5.8 9.2 10.7 21.1 3.7 7.1 2.2 6.9 6.4 2.6 0.2 0.0 10.5 0.1 2.7 6.7 1.1 0.3 0.5 19.6 2.0 0.3 0.0 4.6 4.1 1.1 3.2 2.2 17.5 7.3 0.0 1.4 3.7 6.0 2.8 1.1 3.5 0.1 4.3 26.6 1.5 0.0 9.4 5.2 30.3 2.8 2.9 1.9 0.4 19.5 9.6 0.0 0.5 0.4 1.6 6.7 8.0 7.6 0.0 5.0 7.0 6.3 0.0 0.9 1.0 2.5 0.2 4.3 8.8 1.3 0.2 0.0 3.4 8.9 3.0 0.0 0.0 0.0 0.9 5.9 22.7 4.4 0.1 10.5 4.2 0.0 5.2 0.0 5.0 3.7 0.0 0.2 6.7 3.8 0.1 2.7 0.1 0.0 5.3 1.1 29.0 30.9 21.1 22.2 30.9 14.8 11.4 18.3 13.6 21.1 TNK1 ENSG00000174292 "Tyrosine kinase non receptor 1" Q13470 17 7380534-7389774 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 6.4;HaCaT: 10.4;HBEC3-KT: 6.9;hTCEpi: 7.8;T-47d: 8.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 6.4;cerebellum: 11.4;cerebral cortex: 4.0;pons and medulla: 4.3" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "B-cells: 1.6;T-cells: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012065, HPA056452" Uncertain Approved "Cell Junctions" "Cell Junctions" "HPA012065: AB_1858165, HPA056452: " "unprognostic (4.90e-2)" "unprognostic (1.93e-1)" "unprognostic (2.95e-1)" "prognostic favourable (4.28e-4)" "unprognostic (2.84e-1)" "unprognostic (1.60e-1)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.20e-1)" "unprognostic (2.52e-2)" "unprognostic (2.43e-1)" "unprognostic (3.10e-1)" "prognostic favourable (6.40e-4)" "unprognostic (1.77e-3)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" "prognostic favourable (1.52e-4)" 3.4 0.6 1.1 2.2 6.4 0.4 7.9 11.4 4.0 5.4 11.7 0.4 7.7 7.1 5.1 5.3 7.2 3.5 6.3 2.0 1.0 0.4 4.6 6.9 3.2 2.7 1.5 0.8 4.4 6.8 5.4 2.7 2.5 4.3 8.9 4.5 7.7 10.5 4.8 1.8 8.3 11.3 5.1 0.7 2.4 9.6 2.2 0.6 0.6 11.6 5.7 5.2 4.5 4.4 1.6 0.1 0.4 0.0 0.0 3.8 0.6 6.4 1.0 0.2 0.4 0.0 0.0 4.3 0.2 0.0 0.4 0.4 3.3 3.0 0.0 2.6 0.3 10.4 0.0 6.9 0.1 0.7 1.5 0.0 3.7 1.8 0.4 0.0 0.2 0.1 7.8 0.0 1.2 0.0 0.8 0.0 0.0 4.9 0.6 0.0 0.9 0.9 0.2 0.2 0.7 4.8 3.0 0.2 0.5 3.5 5.2 1.0 8.6 0.1 1.7 0.2 0.8 0.2 0.0 0.5 1.0 0.1 0.1 0.4 0.5 0.0 0.0 0.0 1.0 0.0 1.9 1.6 1.8 1.2 0.1 1.5 3.3 3.8 0.4 0.0 0.0 0.0 0.8 0.6 1.1 6.4 11.4 4.0 1.0 0.4 1.5 0.8 4.3 0.6 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041954 Approved Approved Cytosol Cytosol "HPA041954: AB_10794164" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavourable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavourable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favourable (1.00e-4)" 9.2 7.6 36.3 16.2 27.6 38.9 8.5 20.7 43.7 6.0 6.3 17.6 3.8 6.6 8.0 6.6 13.0 10.7 6.5 10.6 28.4 21.8 4.1 7.2 9.3 18.1 21.6 31.8 8.6 7.8 5.1 19.3 8.4 20.0 10.8 3.9 5.3 16.8 8.2 30.5 37.1 6.9 7.6 10.3 17.0 12.1 7.7 21.8 3.4 4.6 9.8 12.8 7.7 12.3 6.1 3.1 6.3 3.2 0.9 1.9 1.2 31.3 3.0 5.1 5.4 7.1 4.5 30.5 6.0 5.8 3.6 3.3 4.8 24.3 9.1 21.2 8.2 11.2 4.4 7.5 1.1 21.4 5.6 8.2 10.2 3.5 3.2 4.2 4.1 3.3 11.9 5.0 6.0 4.6 3.3 12.7 3.4 23.1 1.8 15.4 4.8 11.3 5.3 6.1 9.2 3.2 15.2 6.2 6.3 3.9 15.9 7.8 26.0 5.3 7.5 8.4 4.9 4.4 16.8 27.6 3.0 5.6 7.5 13.8 6.2 2.0 2.4 0.9 1.9 3.2 1.1 2.7 1.8 1.0 1.1 6.1 1.4 1.3 6.3 0.9 2.8 3.1 0.2 1.2 36.3 27.6 20.7 33.3 28.4 21.8 21.6 31.8 20.0 21.8 TNKS "PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1" ENSG00000173273 Tankyrase O95271 8 9555914-9782346 "Enzymes, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport, Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025690 Approved Approved "Nucleoplasm,Nuclear membrane" Nucleoplasm "Nuclear membrane" "HPA025690: AB_10602249" "unprognostic (2.07e-1)" "unprognostic (1.72e-2)" "unprognostic (5.45e-3)" "unprognostic (8.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.27e-2)" "unprognostic (4.75e-2)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (8.01e-2)" "unprognostic (6.21e-2)" "unprognostic (9.10e-2)" "unprognostic (4.14e-2)" "unprognostic (1.12e-1)" "unprognostic (5.43e-1)" "unprognostic (7.76e-2)" "unprognostic (5.36e-2)" 9.1 13.4 17.8 8.7 19.6 14.6 14.0 26.5 22.3 18.1 8.9 17.0 12.5 8.5 14.9 25.3 7.7 11.9 8.9 9.5 18.6 17.9 9.0 9.1 10.3 12.9 28.7 17.2 19.2 10.2 23.9 20.0 11.0 20.1 11.5 10.0 10.9 9.4 11.7 22.1 15.6 9.8 11.0 21.0 8.7 10.1 26.3 21.8 15.6 13.7 4.4 11.7 10.8 13.6 6.8 3.6 7.4 2.8 2.9 4.8 1.2 6.0 8.0 20.5 12.3 12.9 17.4 7.6 9.3 10.6 7.6 8.6 4.7 4.8 12.9 3.9 9.1 6.4 11.6 8.7 11.0 3.3 6.0 9.1 7.3 10.7 11.7 4.7 5.6 12.3 10.6 7.9 15.6 10.2 8.5 13.9 14.0 3.9 11.7 7.1 13.3 4.7 9.5 12.6 3.7 9.1 12.3 20.8 15.3 7.3 7.0 13.2 4.7 7.0 13.7 12.5 7.7 8.5 6.9 4.8 7.8 9.2 13.5 6.6 12.0 4.8 2.3 1.8 4.4 2.2 2.4 4.2 3.5 4.2 2.8 6.8 4.2 4.8 7.4 2.9 2.8 3.6 1.7 1.2 17.8 19.6 26.5 22.3 18.6 17.9 28.7 17.2 20.1 21.8 TNKS2 "PARP-5b, PARP-5c, PARP5B, PARP5C, pART6, TANK2, TNKL" ENSG00000107854 "Tankyrase 2" Q9H2K2 10 91798312-91865276 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036606 Approved Microtubules Microtubules "HPA036606: AB_10673470" "unprognostic (1.12e-1)" "unprognostic (2.66e-1)" "unprognostic (4.16e-1)" "unprognostic (1.61e-2)" "unprognostic (3.07e-2)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "unprognostic (2.93e-1)" "unprognostic (2.59e-2)" "unprognostic (1.50e-1)" "unprognostic (2.26e-2)" "unprognostic (1.00e-1)" "unprognostic (2.35e-1)" "unprognostic (1.69e-1)" "unprognostic (7.97e-2)" "unprognostic (2.53e-1)" 17.6 16.3 16.7 23.0 18.6 26.9 18.4 27.9 20.0 18.8 13.9 18.3 18.3 11.9 18.9 18.8 24.7 16.7 17.2 12.2 16.6 14.9 14.6 16.8 17.0 22.9 20.3 14.9 26.0 19.3 20.8 26.7 47.5 16.1 16.7 14.3 16.1 21.4 16.0 39.7 23.9 16.5 18.9 18.0 22.8 15.8 9.5 17.9 42.9 24.5 21.0 23.8 18.6 18.9 3.6 5.2 3.8 2.5 3.3 3.5 1.4 14.3 12.3 25.3 21.4 17.9 16.4 28.3 15.5 28.4 19.0 23.4 10.9 11.8 13.6 7.5 20.2 15.6 15.8 12.0 26.9 13.7 15.3 11.2 11.8 12.1 17.5 21.6 16.8 16.6 15.9 19.2 34.3 17.8 8.3 15.1 19.7 7.7 18.6 14.8 12.7 8.3 17.5 15.8 10.3 13.0 15.6 6.6 11.9 15.6 6.9 19.3 16.7 15.1 19.1 10.3 8.7 13.5 14.7 19.1 15.6 17.7 13.5 16.3 9.1 1.0 2.5 3.8 3.5 2.3 3.0 3.5 3.3 3.2 3.4 3.6 2.8 2.4 2.5 3.3 2.2 5.2 1.7 1.4 16.7 18.6 27.9 20.0 16.6 14.9 20.3 14.9 16.1 17.9 TOP1 ENSG00000198900 "DNA topoisomerase I" P11387 20 41028818-41124487 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009058, HPA019039" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "CAB009058: AB_2303554, HPA019039: AB_1858187" "unprognostic (1.46e-1)" "unprognostic (8.65e-2)" "unprognostic (1.33e-2)" "unprognostic (1.92e-3)" "unprognostic (5.05e-2)" "unprognostic (1.49e-3)" "prognostic unfavourable (6.42e-4)" "unprognostic (5.86e-2)" "unprognostic (1.51e-1)" "unprognostic (4.60e-2)" "unprognostic (3.74e-3)" "unprognostic (6.51e-2)" "unprognostic (8.65e-2)" "unprognostic (4.70e-2)" "unprognostic (5.14e-1)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" 26.6 31.0 24.6 46.3 25.3 55.3 37.4 39.6 31.1 21.3 30.0 11.1 26.7 29.7 22.9 22.5 36.0 20.5 29.2 21.0 23.0 18.3 31.8 32.7 37.9 38.6 21.9 20.9 25.5 22.5 22.2 39.9 43.9 25.2 23.3 27.2 13.6 25.3 34.3 26.2 24.6 48.4 23.1 27.4 36.9 26.7 14.2 24.2 54.2 31.5 25.1 40.6 25.2 41.7 9.0 17.2 18.4 11.1 5.8 8.2 4.6 21.5 15.1 28.3 23.1 11.5 13.7 28.0 19.5 17.2 22.7 20.7 39.6 27.2 61.5 20.9 10.1 21.0 33.9 31.2 33.3 13.3 17.3 78.4 12.1 28.1 29.9 33.8 27.0 15.5 16.7 22.1 36.4 23.7 34.0 21.4 25.6 47.9 47.7 21.4 22.8 28.1 40.8 26.6 32.7 24.2 20.1 23.5 16.3 30.6 19.0 19.8 21.1 30.3 23.2 18.4 15.6 17.0 20.9 13.6 15.2 71.7 24.7 19.0 17.4 9.1 9.2 14.3 6.5 9.2 8.2 9.0 7.2 6.8 8.6 8.7 7.7 6.9 18.4 5.8 11.1 17.2 7.9 4.6 24.6 25.3 39.6 31.1 23.0 18.3 21.9 20.9 25.2 24.2 TOP1MT ENSG00000184428 "DNA topoisomerase I mitochondrial" Q969P6 8 143304384-143359979 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001915, HPA021542" Approved Supported Mitochondria Mitochondria "HPA001915: AB_1080331, HPA021542: AB_1858186" "unprognostic (5.02e-3)" "unprognostic (3.79e-2)" "unprognostic (6.57e-2)" "unprognostic (6.92e-3)" "unprognostic (2.32e-2)" "unprognostic (1.04e-2)" "unprognostic (3.05e-3)" "unprognostic (1.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.42e-2)" "prognostic unfavourable (1.52e-7)" "unprognostic (3.66e-2)" "unprognostic (3.62e-2)" "unprognostic (8.55e-3)" "unprognostic (5.66e-3)" 11.7 13.5 8.1 13.7 9.8 33.0 22.1 2.2 10.3 14.7 10.7 4.5 3.9 6.0 10.0 7.4 14.9 11.3 11.0 5.9 8.8 5.6 9.6 22.5 8.5 11.4 6.9 8.1 27.0 15.9 5.9 8.6 5.9 7.3 14.7 8.0 5.9 11.0 10.8 5.7 15.4 8.3 8.8 6.8 11.4 9.3 18.1 6.4 25.1 19.2 9.6 11.4 14.0 30.9 16.7 18.8 11.7 5.5 0.2 14.3 4.7 7.5 11.6 4.9 18.2 7.0 7.8 8.7 3.5 4.5 6.4 6.6 14.5 10.9 22.2 13.2 4.9 8.1 10.4 6.5 5.5 8.7 15.9 19.5 6.5 14.6 7.9 13.0 21.2 7.9 6.9 5.3 7.8 7.6 23.3 8.7 5.6 31.5 57.7 25.9 8.5 19.9 7.3 6.4 33.2 4.7 12.2 8.7 10.6 10.0 9.0 18.1 5.9 21.7 5.0 4.4 18.1 5.0 9.0 4.7 4.9 11.3 7.5 19.5 5.3 11.7 5.5 0.2 3.5 3.2 3.6 16.7 6.4 4.8 18.8 8.0 14.3 10.4 0.4 0.2 0.6 16.4 1.7 4.7 8.1 9.8 2.2 10.3 8.8 5.6 6.9 8.1 7.3 6.4 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388516-40417950 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 146.3;testis: 36.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 5.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavourable (5.92e-6)" "prognostic unfavourable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavourable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.7 2.0 0.4 20.0 0.5 14.6 4.1 0.4 0.5 3.0 6.9 0.5 0.5 7.0 2.0 3.4 18.2 0.7 2.4 2.3 0.6 0.5 1.4 1.9 5.5 15.4 0.6 0.4 1.2 1.1 0.0 0.4 10.7 0.6 1.2 8.0 0.6 3.2 0.3 0.6 5.9 9.2 2.6 1.8 7.3 4.5 36.8 0.3 146.3 0.9 11.8 16.7 3.2 5.7 1.3 0.3 0.3 0.3 3.2 5.7 1.1 33.7 44.9 57.2 26.1 2.8 5.8 12.7 46.4 25.0 42.7 37.9 21.0 25.9 54.5 23.6 15.7 53.8 43.9 18.5 57.4 29.1 29.3 36.0 28.7 35.1 0.2 50.4 38.3 1.2 1.5 30.0 30.6 22.4 38.9 37.4 46.1 11.7 58.4 33.9 23.7 17.9 49.6 88.8 22.6 10.3 21.6 33.8 24.3 37.4 46.7 14.7 39.2 23.2 14.7 28.2 39.7 32.5 44.5 21.5 24.3 47.6 15.9 34.8 46.9 0.3 0.0 0.0 0.6 0.0 0.0 1.3 0.9 0.9 0.3 0.4 0.2 0.1 0.3 3.2 0.3 0.0 5.7 1.1 0.4 0.5 0.4 0.5 0.6 0.5 0.6 0.4 0.6 0.3 TOP2B ENSG00000077097 "DNA topoisomerase II beta" Q02880 3 25597905-25664907 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Autism spectrum disorder, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 104.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004601, HPA024120, HPA050441" Supported Enhanced Nucleoplasm Nucleoplasm "CAB004601: AB_628384, HPA024120: AB_1858191, HPA050441: AB_2681127" "unprognostic (2.90e-2)" "unprognostic (5.17e-2)" "unprognostic (7.21e-3)" "unprognostic (2.42e-1)" "unprognostic (1.60e-1)" "unprognostic (1.43e-2)" "prognostic unfavourable (1.86e-7)" "unprognostic (7.86e-2)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (7.14e-2)" "unprognostic (1.08e-1)" "prognostic favourable (2.43e-4)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (1.49e-1)" "unprognostic (7.93e-2)" 19.3 18.8 23.4 23.1 29.7 26.5 21.1 48.4 33.5 24.1 22.4 21.1 18.9 17.1 29.6 25.6 21.1 20.6 20.7 22.7 22.0 19.9 20.3 18.4 17.7 28.2 21.0 28.5 26.8 17.2 43.0 21.6 22.3 26.4 24.7 20.8 17.6 21.3 22.3 31.3 20.9 19.3 24.4 23.4 24.6 20.1 11.3 22.7 60.2 28.3 20.7 27.3 34.8 21.5 5.5 5.6 5.3 4.6 7.8 7.2 2.2 10.5 10.9 24.1 29.5 8.0 10.2 9.6 10.2 13.1 9.5 10.4 5.5 8.4 32.6 7.1 14.7 9.0 20.0 11.3 16.0 15.6 10.7 49.5 13.6 9.3 5.6 38.7 26.5 7.3 5.7 10.6 9.3 15.4 16.6 16.1 12.2 11.7 25.0 9.6 18.3 8.3 104.7 13.6 15.1 8.5 37.2 12.2 21.1 15.2 10.9 9.3 11.3 34.6 14.7 13.2 10.3 10.5 10.9 24.9 14.1 34.7 8.7 29.0 8.8 4.2 2.9 5.3 6.3 3.3 6.9 4.3 6.1 6.4 4.3 5.5 7.2 6.4 2.0 7.8 4.6 5.6 4.4 2.2 23.4 29.7 48.4 33.5 22.0 19.9 21.0 28.5 26.4 22.7 TOP3A "TOP3, ZGRF7" ENSG00000177302 "DNA topoisomerase III alpha" Q13472 17 18271428-18315007 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, Disease mutation, Dwarfism, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002449 Approved "CAB002449: AB_564037" "unprognostic (5.49e-2)" "unprognostic (9.04e-2)" "unprognostic (8.99e-2)" "unprognostic (7.24e-3)" "unprognostic (4.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.33e-3)" "unprognostic (6.54e-2)" "unprognostic (2.34e-1)" "unprognostic (2.74e-1)" "prognostic favourable (1.39e-4)" "prognostic unfavourable (4.59e-4)" "unprognostic (5.58e-2)" "unprognostic (8.80e-2)" "unprognostic (3.53e-2)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" 12.5 11.6 10.9 12.5 14.0 23.8 12.0 21.4 17.9 11.0 11.2 13.8 9.1 10.3 13.3 10.4 12.1 11.8 9.5 8.4 9.3 10.5 9.3 15.6 10.8 15.5 9.4 9.0 11.4 16.1 15.0 15.1 10.7 11.1 11.0 13.1 12.8 11.6 9.0 13.0 19.1 10.8 14.1 9.0 16.6 10.5 17.9 11.8 25.9 10.3 7.4 16.2 11.6 10.7 2.1 2.7 10.4 5.9 4.1 4.0 3.3 8.1 13.7 11.2 13.6 5.7 5.8 10.2 8.6 6.2 15.2 15.0 24.9 3.6 14.1 5.6 7.8 11.5 16.8 7.3 16.1 10.4 13.5 12.9 14.2 8.5 5.7 6.4 11.5 3.7 4.7 16.1 9.4 7.0 11.1 5.8 8.8 8.4 14.3 8.1 8.7 7.6 16.3 26.7 13.3 4.5 8.4 8.0 15.0 13.2 8.3 8.5 16.6 6.8 6.7 10.9 8.7 20.7 14.8 6.4 11.5 9.9 6.8 8.9 10.4 1.4 5.9 6.5 4.0 5.8 2.6 1.7 3.0 3.1 2.6 2.1 2.6 2.7 10.4 4.1 2.9 2.7 2.2 3.3 10.9 14.0 21.4 17.9 9.3 10.5 9.4 9.0 11.1 11.8 TOP3B ENSG00000100038 "DNA topoisomerase III beta" O95985 22 21957025-21982816 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 48.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072114 Approved Nucleoplasm Nucleoplasm "HPA072114: " "unprognostic (1.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (3.37e-1)" "unprognostic (5.04e-2)" "unprognostic (2.27e-1)" "unprognostic (3.93e-1)" "unprognostic (2.15e-2)" "unprognostic (2.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-2)" "unprognostic (1.96e-2)" "unprognostic (1.69e-2)" "unprognostic (1.21e-1)" "unprognostic (3.53e-2)" "unprognostic (1.11e-4)" 10.4 11.7 12.1 16.1 17.4 20.8 10.9 17.2 17.1 12.5 11.0 16.9 14.9 15.4 16.1 11.0 14.2 11.0 11.2 10.1 12.7 5.5 13.4 15.3 12.7 17.0 18.7 6.5 20.2 12.1 13.5 21.0 12.1 16.2 15.6 14.9 14.1 13.3 13.3 13.4 17.5 16.1 14.5 17.4 23.6 11.8 11.1 16.9 13.1 14.2 5.7 18.9 10.5 14.3 9.0 8.8 2.7 6.8 6.1 9.3 5.2 9.5 9.1 18.7 7.4 6.9 5.8 11.7 6.4 7.9 14.7 13.1 9.9 4.1 13.1 4.8 6.6 17.5 8.4 11.2 11.9 6.7 20.2 10.3 11.8 10.2 9.4 14.0 6.8 2.8 17.3 12.1 5.9 12.2 48.2 7.2 6.9 9.7 8.8 10.9 7.7 8.8 13.8 12.4 2.0 7.3 12.8 12.2 8.9 7.8 6.9 5.9 5.4 9.0 8.9 6.1 12.7 5.7 7.7 10.6 8.6 12.4 4.7 8.6 6.2 2.5 6.7 2.7 9.3 6.8 6.5 7.5 5.8 6.5 7.4 9.0 5.9 5.7 2.3 6.1 3.8 8.8 6.7 5.2 12.1 17.4 17.2 17.1 12.7 5.5 18.7 6.5 16.2 16.9 TOPORS "LUN, RP31, TP53BPL" ENSG00000197579 "TOP1 binding arginine/serine rich protein" Q9NS56 9 32540544-32552553 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 33.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060640, HPA065661" Supported Supported Nucleoplasm Nucleoplasm "HPA060640: , HPA065661: " "unprognostic (1.75e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.37e-2)" "unprognostic (9.94e-2)" "prognostic favourable (7.07e-4)" "unprognostic (2.70e-1)" "unprognostic (3.61e-1)" "prognostic favourable (6.64e-6)" "unprognostic (1.22e-1)" "unprognostic (5.95e-2)" "unprognostic (3.13e-1)" "unprognostic (2.92e-1)" 16.0 12.5 12.7 8.5 16.0 22.9 13.7 18.6 15.1 14.0 12.2 9.6 9.5 8.8 12.9 11.4 13.1 10.5 11.7 9.3 15.9 9.6 14.6 17.4 10.6 10.0 20.1 5.2 17.5 13.2 19.6 19.5 17.9 14.8 13.1 10.3 9.2 11.0 10.8 10.9 10.2 16.8 12.3 17.8 12.4 10.7 18.9 15.0 15.5 15.6 9.8 10.5 16.3 16.0 5.2 4.9 33.4 5.9 7.1 7.4 3.4 8.0 7.5 10.3 9.0 12.6 11.4 6.5 10.3 9.7 8.6 10.0 4.6 4.1 13.1 5.9 10.2 5.4 12.1 11.7 12.1 10.9 6.6 44.2 13.0 5.8 7.8 12.5 12.2 9.2 13.1 12.4 8.8 10.4 7.6 6.8 13.9 4.3 11.2 23.1 13.7 7.6 11.6 9.2 5.9 11.4 8.5 5.1 8.2 10.3 5.6 6.7 5.7 7.2 10.9 9.4 9.6 4.9 7.6 4.8 7.7 14.2 8.7 7.2 4.2 14.6 4.9 10.0 5.0 4.6 5.4 4.6 5.4 5.8 4.9 5.2 7.4 7.2 33.4 7.1 5.9 4.0 6.3 3.4 12.7 16.0 18.6 15.1 15.9 9.6 20.1 5.2 14.8 15.0 TP53RK "BUD32, C20orf64, dJ101A2.2, Nori-2p, prpk" ENSG00000172315 "TP53 regulating kinase" Q96S44 20 46684365-46689779 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004688, HPA015837" Approved "CAB004688: AB_426116, HPA015837: AB_1855776" "unprognostic (9.45e-2)" "unprognostic (3.73e-1)" "unprognostic (9.76e-2)" "prognostic unfavourable (6.70e-5)" "unprognostic (4.41e-2)" "unprognostic (2.63e-1)" "prognostic unfavourable (6.27e-5)" "unprognostic (9.16e-3)" "unprognostic (6.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.36e-1)" "unprognostic (5.72e-2)" "unprognostic (1.25e-2)" "unprognostic (3.37e-2)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (1.74e-2)" 11.2 14.5 12.7 12.6 15.3 9.6 16.8 8.1 20.3 14.1 11.7 13.7 5.3 8.8 14.8 8.9 16.9 12.2 12.6 9.9 12.1 11.3 12.7 13.6 10.6 18.2 13.1 12.8 15.3 10.1 11.8 15.7 14.9 12.1 15.5 11.4 12.6 13.8 12.2 12.4 16.8 11.2 12.7 10.6 13.2 13.3 26.4 11.8 21.9 16.6 13.1 21.1 14.3 12.7 14.7 19.1 21.7 12.4 16.2 18.5 12.2 3.9 2.7 5.8 5.1 6.1 5.1 5.2 5.5 5.2 7.4 5.4 7.7 2.5 9.5 8.4 4.6 6.2 7.4 6.4 6.4 2.3 3.7 9.6 2.7 6.9 8.1 6.2 69.0 6.7 7.8 5.1 5.0 4.8 6.4 4.2 6.2 5.8 9.3 10.3 4.7 9.2 5.4 5.2 5.6 4.9 4.3 6.9 3.6 6.7 13.6 27.0 4.9 6.8 4.9 8.6 5.0 5.6 6.1 4.6 5.7 7.6 5.0 4.7 4.0 21.7 12.4 20.6 13.7 11.5 15.8 14.7 14.8 15.6 12.6 14.2 16.4 14.0 2.0 16.2 10.2 19.1 18.5 12.2 12.7 15.3 8.1 20.3 12.1 11.3 13.1 12.8 12.1 11.8 TPH1 "TPH, TPRH" ENSG00000129167 "Tryptophan hydroxylase 1" P17752 11 18017564-18042426 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Serotonin biosynthesis" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 4.2;intestine: 16.2;pituitary gland: 5.4;stomach 1: 13.3" "Cell line enhanced" "Detected in many" "HL-60: 4.5" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 6 "cerebral cortex: 4.2" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB010767, HPA022483" Approved Uncertain Cytosol Cytosol "CAB010767: AB_261587, HPA022483: AB_1858378" "unprognostic (2.14e-4)" "unprognostic (9.97e-2)" "unprognostic (6.92e-2)" "unprognostic (6.78e-2)" "unprognostic (1.55e-1)" "unprognostic (6.26e-5)" "unprognostic (1.73e-1)" "unprognostic (5.33e-2)" "unprognostic (1.60e-1)" "unprognostic (2.12e-2)" "unprognostic (1.19e-4)" "unprognostic (6.72e-2)" "unprognostic (5.40e-8)" "unprognostic (3.76e-2)" "unprognostic (7.42e-2)" "unprognostic (3.10e-1)" "unprognostic (2.46e-5)" 0.7 0.0 0.7 0.7 0.7 0.6 0.9 0.7 4.2 0.7 7.1 0.7 0.7 8.2 0.7 0.7 0.7 1.5 0.7 0.7 0.7 0.3 0.7 0.7 0.7 0.7 0.7 0.7 1.0 0.7 0.0 5.4 0.7 0.7 1.3 16.2 0.7 0.7 0.7 0.7 1.0 9.1 0.7 0.7 1.0 13.3 0.9 0.7 0.7 0.7 0.7 0.7 0.7 0.7 1.4 0.8 1.5 0.5 0.9 1.6 0.2 0.4 0.1 1.7 1.5 0.1 0.0 0.6 0.6 0.5 0.2 1.1 1.8 0.3 1.4 0.3 0.0 0.6 0.4 1.5 0.7 1.3 3.1 2.2 0.8 3.5 0.0 4.5 1.2 0.0 1.8 0.2 0.6 0.7 0.9 0.8 0.1 0.5 1.0 0.7 0.5 0.3 1.7 0.3 0.0 0.0 1.0 1.3 0.9 0.2 0.4 0.9 0.3 2.9 0.2 0.4 1.3 0.5 1.7 0.2 0.3 1.1 0.2 1.0 1.4 1.5 0.4 0.4 1.6 0.2 0.8 0.5 0.5 0.4 0.1 1.4 0.6 0.6 1.5 0.9 0.5 0.8 0.6 0.2 0.7 0.7 0.7 4.2 0.7 0.3 0.7 0.7 0.7 0.7 TPH2 "FLJ37295, NTPH" ENSG00000139287 "Tryptophan hydroxylase 2" Q8IWU9 12 71938846-72186618 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Serotonin biosynthesis" "Monooxygenase, Oxidoreductase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 46.2" "Group enriched" "Detected in some" 9 "EFO-21: 2.8;NTERA-2: 3.1;SCLC-21H: 1.5" "Not detected" "Not detected" "Region enriched" "Detected in many" 15 "pons and medulla: 46.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "midbrain: 127.6;pons and medulla: 36.3" "Group enriched" "Detected in some" 10 "midbrain: 95.6;pons and medulla: 91.5" CAB078198 Enhanced "CAB078198: " "unprognostic (1.19e-1)" "unprognostic (6.01e-1)" "unprognostic (3.46e-2)" "unprognostic (2.31e-1)" "unprognostic (5.91e-2)" "unprognostic (2.02e-1)" "unprognostic (5.01e-2)" "unprognostic (7.32e-2)" "unprognostic (1.34e-1)" 0.1 0.2 0.4 0.3 0.5 0.1 0.1 0.3 4.4 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.2 3.0 1.5 0.1 0.3 0.1 0.1 0.9 0.0 0.1 1.7 0.1 3.2 0.1 46.2 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.2 0.3 0.1 0.1 1.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.3 1.4 3.0 1.5 0.9 0.0 46.2 0.0 TPI1 ENSG00000111669 "Triosephosphate isomerase 1" P60174 12 6867119-6870948 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Glycolysis" "Isomerase, Lyase" "Cancer-related genes, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 234.8;skeletal muscle: 211.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050924, HPA053568" Uncertain Approved Nucleoplasm,Vesicles 270000000 Nucleoplasm Vesicles "HPA050924: AB_2681276, HPA053568: AB_2682193" "unprognostic (2.85e-1)" "unprognostic (5.58e-3)" "unprognostic (1.65e-1)" "unprognostic (1.62e-2)" "unprognostic (6.94e-2)" "unprognostic (2.31e-2)" "prognostic unfavourable (1.04e-5)" "unprognostic (4.14e-3)" "unprognostic (7.49e-2)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "prognostic unfavourable (6.54e-4)" "unprognostic (7.04e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" 20.2 41.2 41.2 24.3 46.9 27.4 83.4 93.2 196.1 27.1 39.1 12.8 18.6 40.1 17.2 22.6 51.0 22.1 33.3 94.9 36.7 33.1 43.1 40.8 48.8 140.2 34.0 34.6 19.9 87.0 32.1 16.8 27.1 70.7 19.0 43.5 21.1 26.0 28.7 211.0 25.8 37.8 29.4 20.8 20.1 21.6 15.7 19.4 14.2 20.2 38.4 38.0 23.0 28.0 55.4 170.3 145.5 148.2 81.2 67.1 234.8 119.2 106.9 56.6 87.6 55.5 58.6 100.1 86.3 95.3 163.1 197.9 110.3 65.6 70.0 17.4 85.1 59.4 134.6 144.2 181.0 92.3 100.3 90.7 78.3 72.7 41.4 103.2 74.5 63.6 60.2 125.8 108.4 99.1 46.9 26.9 125.2 87.8 54.2 87.2 139.7 68.1 31.9 93.2 71.8 102.1 85.1 40.3 67.1 75.3 78.4 41.8 17.9 77.6 61.2 87.5 75.0 56.6 126.5 52.6 21.6 104.6 175.6 64.2 62.7 87.7 146.1 145.5 56.1 148.2 57.0 55.4 56.5 54.5 170.3 44.3 39.9 49.3 61.1 81.2 127.8 30.7 67.1 234.8 41.2 46.9 93.2 196.1 36.7 33.1 34.0 34.6 70.7 19.4 TPK1 "HTPK1, PP20" ENSG00000196511 "Thiamin pyrophosphokinase 1" Q9H3S4 7 144451941-144836395 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "AN3-CA: 26.6;CACO-2: 6.3;EFO-21: 8.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021545, HPA021849" Approved Approved Vesicles 78000 Vesicles "HPA021545: AB_1858209, HPA021849: AB_1858210" "unprognostic (4.05e-2)" "unprognostic (3.28e-2)" "unprognostic (2.38e-2)" "unprognostic (3.32e-2)" "unprognostic (2.42e-1)" "unprognostic (1.63e-1)" "unprognostic (7.62e-2)" "unprognostic (6.08e-2)" "unprognostic (2.37e-1)" "unprognostic (1.68e-1)" "unprognostic (3.76e-2)" "unprognostic (6.06e-2)" "unprognostic (1.45e-3)" "unprognostic (3.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (9.22e-3)" 12.2 7.4 5.1 9.6 4.7 3.6 7.6 4.0 7.2 4.3 8.4 4.2 2.4 18.2 5.1 5.0 3.3 3.9 5.4 6.4 5.6 6.6 6.0 6.2 8.8 23.3 4.9 3.1 4.4 3.3 3.6 4.6 7.0 4.4 3.7 8.5 8.9 7.1 4.1 3.0 2.9 13.9 5.1 6.0 15.1 4.0 5.9 2.0 5.1 4.9 4.1 14.2 5.5 3.3 5.4 9.6 3.4 7.4 4.0 5.5 3.8 0.2 0.2 0.2 26.6 0.2 0.2 2.2 0.1 0.1 0.0 0.0 6.3 1.0 0.4 8.1 0.4 0.0 0.5 0.3 0.2 1.6 0.4 0.1 0.1 0.1 0.7 2.0 0.6 0.5 0.5 0.3 0.4 5.1 0.5 1.2 0.1 0.8 0.5 3.0 0.6 2.2 0.2 0.6 0.9 4.1 2.3 0.2 0.0 0.4 0.0 0.4 0.3 3.8 6.1 0.3 0.6 0.5 0.3 0.6 1.4 0.6 0.9 5.1 0.2 0.3 7.3 0.2 3.9 5.3 4.0 5.0 4.4 3.5 9.6 5.4 5.2 4.2 3.4 4.0 7.4 2.3 5.5 3.8 5.1 4.7 4.0 7.2 5.6 6.6 4.9 3.1 4.4 2.0 TPMT ENSG00000137364 "Thiopurine S-methyltransferase" P51580 6 18128311-18155074 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 48.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019851 Enhanced "HPA019851: AB_1858213" "unprognostic (6.24e-2)" "unprognostic (3.16e-2)" "unprognostic (5.46e-3)" "prognostic unfavourable (8.45e-5)" "unprognostic (4.98e-2)" "unprognostic (2.25e-1)" "unprognostic (8.16e-2)" "unprognostic (4.36e-3)" "unprognostic (9.62e-2)" "prognostic favourable (1.41e-4)" "unprognostic (4.49e-2)" "unprognostic (3.40e-2)" "prognostic favourable (1.10e-4)" "unprognostic (7.56e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" 5.3 13.2 11.5 6.6 10.2 4.9 5.6 13.1 14.3 4.6 18.2 4.1 6.2 18.4 6.5 10.1 8.9 4.1 7.6 6.5 9.0 8.0 40.2 36.2 6.5 6.2 9.3 7.5 3.8 9.4 12.9 11.6 3.3 8.5 6.2 19.4 6.9 12.9 7.2 7.0 5.7 29.4 6.2 7.2 9.4 6.6 4.1 7.5 5.4 48.2 6.3 5.3 6.4 5.6 1.6 16.9 3.7 23.8 5.4 8.3 8.3 11.7 3.6 4.0 9.8 6.6 12.9 9.8 13.7 15.2 11.7 18.3 8.3 2.9 1.5 10.2 18.0 5.9 5.6 9.8 19.6 7.7 8.1 9.7 6.1 12.1 7.2 4.4 8.8 7.4 10.6 13.0 8.3 16.2 19.1 2.8 8.5 5.4 4.5 6.1 6.6 10.3 5.7 9.8 6.6 13.6 12.1 6.5 5.0 8.9 15.9 17.5 11.5 4.5 6.9 26.9 5.2 14.0 19.3 4.1 18.2 3.8 9.6 6.1 26.9 3.4 12.0 3.7 6.5 23.8 8.3 1.5 5.3 6.2 16.9 1.6 4.8 6.5 1.2 5.4 19.6 3.7 8.2 8.3 11.5 10.2 13.1 14.3 9.0 8.0 9.3 7.5 8.5 7.5 TPO TPX ENSG00000115705 "Thyroid peroxidase" P07202 2 1374223-1543711 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "thyroid gland: 411.3" "Group enriched" "Detected in some" 5 "Karpas-707: 14.0;RPMI-8226: 5.9" "Cancer enriched" "Detected in some" 364 "thyroid cancer: 188.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "memory CD4 T-cell: 5.1;T-reg: 3.0" "Lineage enriched" "Detected in single" 21 "T-cells: 5.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA007987, CAB009587" Enhanced "Intracellular and membrane" "CAB009587: , HPA007987: AB_1080270" "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" "unprognostic (2.88e-1)" "unprognostic (1.77e-2)" "unprognostic (3.56e-2)" "unprognostic (9.11e-2)" "unprognostic (2.24e-2)" "unprognostic (1.85e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-4)" "unprognostic (2.61e-2)" "unprognostic (3.29e-1)" "unprognostic (5.44e-4)" "unprognostic (1.21e-1)" "unprognostic (3.73e-2)" "unprognostic (4.98e-3)" "unprognostic (7.10e-3)" 1.1 0.0 0.1 0.1 0.1 0.0 0.9 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.4 1.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.2 0.1 0.5 0.0 0.2 0.1 0.1 7.1 0.2 0.1 0.1 0.1 411.3 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.0 5.1 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 1.4 0.0 0.0 0.1 0.2 0.0 0.0 5.9 0.0 0.0 0.0 0.1 0.0 2.0 0.0 1.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.3 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.0 3.0 0.9 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 TPP1 "CLN2, SCAR7" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612763-6619485 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease mutation, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" 13000000 "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavourable (4.31e-4)" "prognostic unfavourable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavourable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" 37.4 64.6 32.2 28.8 36.2 43.0 23.1 15.1 33.3 24.0 26.8 41.7 13.2 28.0 32.0 22.3 20.3 18.0 26.9 25.6 24.5 25.1 36.0 45.1 35.9 42.3 31.0 29.3 22.0 14.8 35.1 30.0 56.4 25.4 19.4 28.2 43.4 18.4 29.1 15.4 15.5 31.4 42.4 32.8 69.0 19.8 17.9 24.7 21.7 24.0 9.1 26.9 25.6 29.4 9.4 43.5 12.8 38.9 7.0 15.3 26.2 4.9 10.1 5.1 9.6 59.4 32.9 3.9 9.8 46.5 7.6 13.3 4.2 21.3 7.2 6.5 24.7 14.9 10.0 13.7 11.6 7.1 5.7 5.8 5.2 11.2 44.9 8.3 35.3 49.3 22.4 8.9 19.8 32.5 11.0 21.6 22.2 6.1 2.6 10.3 3.6 12.2 6.5 4.3 14.0 13.5 7.8 0.6 3.9 10.5 7.8 18.3 5.2 15.9 37.1 22.0 6.3 19.8 3.5 18.3 17.9 2.5 28.0 19.6 11.5 12.8 37.7 8.9 10.7 38.9 8.7 9.4 8.5 11.0 43.5 8.5 5.8 7.6 6.9 7.0 26.4 24.2 15.3 26.2 32.2 36.2 15.1 33.3 24.5 25.1 31.0 29.3 25.4 24.7 TPP2 TPPII ENSG00000134900 "Tripeptidyl peptidase 2" P29144 13 102597003-102679958 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021069, HPA049630" Approved Supported "Nuclear bodies,Cytosol" 410000 "Nuclear bodies, Cytosol" "HPA021069: AB_1858344, HPA049630: " "unprognostic (4.75e-2)" "unprognostic (4.78e-2)" "unprognostic (9.97e-2)" "unprognostic (1.08e-1)" "unprognostic (2.01e-2)" "unprognostic (4.43e-2)" "unprognostic (2.45e-2)" "unprognostic (8.33e-3)" "unprognostic (5.02e-2)" "unprognostic (1.51e-1)" "unprognostic (3.12e-1)" "unprognostic (2.75e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.95e-2)" "unprognostic (3.43e-3)" 19.9 12.4 10.8 21.4 14.5 24.7 18.1 23.1 18.4 16.8 14.7 12.2 50.3 13.1 20.0 21.8 14.4 16.7 13.5 17.0 11.7 9.7 12.9 22.8 18.4 32.8 11.7 13.8 21.6 16.3 15.7 15.7 19.2 15.3 13.9 21.0 12.9 15.6 34.5 35.7 14.1 17.4 19.2 13.4 20.7 15.4 34.5 14.0 23.8 21.9 16.0 19.7 17.0 16.0 6.0 5.8 9.2 6.9 10.9 12.1 4.7 15.9 6.4 18.5 15.7 12.5 17.3 13.2 16.3 11.9 10.5 13.2 13.5 21.5 17.5 5.6 13.1 15.7 14.3 11.5 19.0 12.2 12.7 33.3 16.8 10.8 10.6 37.6 20.3 13.4 5.2 11.8 15.8 15.0 19.8 19.6 14.8 5.0 17.3 28.2 15.0 8.9 19.2 14.0 15.8 13.6 13.2 17.2 14.1 10.2 17.1 7.3 9.8 42.2 12.0 10.0 7.3 6.4 13.5 19.3 23.3 15.3 16.7 27.2 12.9 9.2 6.0 4.0 9.1 6.9 10.7 6.0 10.3 10.1 5.8 5.5 12.1 11.5 1.3 10.9 5.7 4.6 10.9 4.7 10.8 14.5 23.1 18.4 11.7 9.7 11.7 13.8 15.3 14.0 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240696-1242554 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 173 "HMC-1: 294.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 308 "basophil: 30.8" "Lineage enriched" "Detected in single" 308 "granulocytes: 30.8" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" "CAB016369: AB_628406, CAB022175: , HPA049153: , HPA049554: " "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favourable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 22.4 0.2 1.6 5.8 1.6 0.0 10.6 1.6 1.6 13.9 17.1 1.6 1.6 17.7 18.7 10.4 15.2 6.1 33.1 4.7 1.6 0.0 4.4 2.8 29.2 16.8 1.6 1.6 2.9 4.5 0.0 1.6 1.9 1.6 24.1 10.0 5.1 14.6 6.3 3.6 29.9 31.0 15.0 1.6 1.6 24.5 5.1 1.6 3.1 3.7 3.8 6.9 21.6 16.0 0.0 0.0 30.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 294.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.6 1.6 1.6 1.6 1.6 0.0 1.6 1.6 1.6 1.6 TPSB2 ENSG00000197253 "Tryptase beta 2 (gene/pseudogene)" P20231 16 1227272-1230184 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.2" "Cell line enriched" "Detected in some" 8 "HMC-1: 81.3" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 84 "basophil: 8.4" "Lineage enriched" "Detected in single" 84 "granulocytes: 8.4" "HPA049153, HPA049554" Supported "Secreted to blood" 7500000 "HPA049153: , HPA049554: " "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 1.8 0.0 0.9 1.9 0.9 0.0 4.1 0.9 0.9 8.8 5.3 0.9 0.9 4.9 2.9 0.9 7.7 0.1 16.2 0.9 0.9 0.9 0.9 12.3 2.4 0.9 0.9 0.9 1.3 0.0 0.9 0.9 0.9 2.7 2.3 0.9 6.2 1.2 0.9 3.4 9.7 4.4 0.9 0.9 13.6 0.9 0.9 0.9 0.9 0.9 0.9 4.2 0.9 0.0 0.0 8.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.1 81.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TPSD1 ENSG00000095917 "Tryptase delta 1" Q9BZJ3 16 1256059-1258998 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 48 "HEL: 18.3;HMC-1: 27.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 65 "basophil: 6.4" "Lineage enriched" "Detected in single" 65 "granulocytes: 6.4" "CAB002215, CAB032871, HPA040182, HPA049554" Supported Uncertain "Nuclear speckles" "Intracellular and membrane" "Nuclear speckles" "CAB002215: AB_563870, CAB032871: AB_2206475, HPA040182: , HPA049554: " "unprognostic (5.99e-2)" "unprognostic (3.00e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (8.97e-3)" "unprognostic (1.15e-4)" "unprognostic (1.70e-1)" "unprognostic (5.45e-2)" "unprognostic (9.00e-2)" "unprognostic (2.88e-1)" "unprognostic (4.30e-1)" "unprognostic (2.94e-2)" "unprognostic (2.50e-3)" "unprognostic (3.74e-2)" "unprognostic (4.14e-1)" "unprognostic (3.89e-1)" "unprognostic (7.46e-3)" 6.6 0.1 0.6 3.8 0.6 0.8 3.7 0.6 0.8 3.2 5.6 0.6 0.6 2.7 7.5 3.3 7.6 2.3 13.0 2.0 0.6 0.0 1.3 2.3 17.0 13.7 0.6 0.6 0.6 0.9 0.1 0.6 0.9 0.6 4.3 0.4 3.1 3.6 0.7 1.6 7.8 9.3 4.7 0.6 0.6 15.7 3.5 0.6 1.6 1.1 2.8 2.6 8.9 6.6 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.1 27.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.8 0.6 0.0 0.6 0.6 0.6 0.6 TPSG1 "PRSS31, TMT" ENSG00000116176 "Tryptase gamma 1" Q9NRR2 16 1221651-1225257 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 16.0" "Group enriched" "Detected in some" 9 "HMC-1: 22.3;MCF7: 7.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060458 Enhanced "HPA060458: " "unprognostic (1.86e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-3)" "unprognostic (1.27e-1)" "unprognostic (5.58e-2)" "unprognostic (1.18e-2)" "unprognostic (3.45e-2)" "unprognostic (4.60e-2)" "unprognostic (9.97e-2)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (6.39e-2)" "prognostic unfavourable (1.76e-8)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (8.65e-4)" "unprognostic (5.70e-2)" 1.3 0.6 0.4 4.5 0.4 0.0 3.1 0.4 0.4 0.6 14.4 0.4 0.4 14.0 1.2 0.4 0.7 0.5 1.0 0.4 0.4 0.0 0.4 0.4 0.6 0.4 0.4 0.4 2.0 0.4 0.0 3.2 0.4 0.4 1.1 8.8 0.4 0.4 0.4 0.4 1.1 16.0 1.2 0.4 0.4 1.0 1.3 0.4 0.4 0.4 1.1 0.4 1.4 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205199-66420543 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 21.3;neutrophil: 17.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: " "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavourable (8.16e-6)" "prognostic unfavourable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavourable (3.73e-5)" 15.4 12.8 16.7 9.8 28.2 5.6 11.2 12.2 19.2 34.0 7.7 8.8 3.4 3.4 20.2 13.8 10.8 10.9 34.2 6.6 26.1 22.2 13.4 38.9 9.0 5.9 15.3 12.2 11.5 7.1 8.1 19.6 23.2 28.1 15.5 7.9 9.7 5.4 15.8 2.9 6.2 5.9 35.7 27.5 9.0 10.0 19.6 11.4 0.3 10.7 3.2 5.2 27.2 19.9 6.3 0.1 21.3 1.1 3.9 2.0 0.8 4.2 2.6 6.7 8.6 20.6 16.5 2.1 8.2 18.9 10.1 14.3 8.2 2.5 0.5 6.6 16.7 3.3 6.3 9.3 13.4 1.2 3.6 0.9 6.4 6.3 24.4 0.6 0.7 23.3 7.3 19.3 8.5 12.2 0.4 3.8 15.4 2.3 0.0 1.1 6.1 3.5 2.9 5.4 4.3 10.4 4.6 3.9 16.7 10.3 0.8 22.0 3.3 1.7 23.2 12.9 8.2 9.2 14.8 3.5 4.8 1.7 11.4 2.5 18.2 21.3 1.1 10.7 0.4 0.0 0.3 2.4 0.2 0.3 0.1 6.3 1.1 2.0 17.3 3.9 0.0 0.0 0.0 0.8 16.7 28.2 12.2 19.2 26.1 22.2 15.3 12.2 28.1 11.4 TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521983-26596717 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 71.0;pancreas: 192.5" "Cell line enhanced" "Detected in all" "HMC-1: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" 33000 "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favourable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavourable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" 5.8 8.4 4.7 3.7 3.6 5.2 9.0 2.1 6.9 4.6 2.9 3.0 7.4 3.5 4.7 31.8 4.5 4.1 3.2 5.2 5.2 3.2 5.7 20.0 10.7 4.8 3.7 3.6 2.4 192.5 1.1 2.9 11.0 3.2 3.8 2.3 4.0 2.8 7.9 8.6 4.0 3.1 3.2 2.8 8.9 3.0 4.8 3.1 3.0 12.2 2.2 5.2 4.5 6.7 4.3 20.0 71.0 15.1 57.2 46.4 35.2 4.2 3.1 4.1 2.0 8.8 6.7 5.7 9.6 17.3 7.8 7.2 2.1 2.2 7.2 2.5 17.2 6.7 3.0 6.6 4.5 2.9 5.8 17.4 1.9 4.4 3.6 2.0 56.0 7.2 10.6 7.9 2.7 14.4 17.4 22.7 5.9 4.8 8.0 13.6 5.3 3.1 7.5 5.5 20.1 2.3 4.8 3.1 2.1 4.4 3.9 5.3 1.8 8.4 11.4 9.7 21.9 7.9 9.2 7.4 10.2 6.9 7.3 7.8 8.7 71.0 13.4 18.6 46.4 14.5 13.0 4.1 10.9 34.5 8.4 4.3 5.4 31.4 28.4 57.2 15.1 20.0 12.2 35.2 4.7 3.6 2.1 6.9 5.2 3.2 3.7 3.6 3.2 3.1 TPTE "CT44, PTEN2" ENSG00000274391 "Transmembrane phosphatase with tensin homology" P56180 21 10521553-10606140 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 69 "testis: 78.6" "Cell line enhanced" "Detected in some" "BEWO: 7.5;K-562: 8.7;Karpas-707: 7.1;MCF7: 5.2;PC-3: 5.3;RPMI-8226: 9.6;U-2 OS: 4.7;U-266/70: 8.6" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049690, HPA068342" Enhanced Approved "Endoplasmic reticulum,Cytosol" Cytosol "Endoplasmic reticulum" "HPA049690: , HPA068342: " "unprognostic (3.63e-2)" 0.1 0.0 0.0 0.7 0.2 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.8 0.4 0.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.4 0.0 0.9 0.0 78.6 0.0 0.4 0.1 0.4 0.8 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 7.1 0.0 5.2 0.0 0.0 1.2 5.3 0.0 0.0 9.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 4.7 2.4 0.0 8.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 TPTE2 TPIP ENSG00000132958 "Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2" Q6XPS3 13 19422877-19536762 "Enzymes, Plasma proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 12.3" "Group enriched" "Detected in some" 4 "HDLM-2: 9.9;Karpas-707: 2.9" "Cancer enriched" "Detected in single" 6 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA068342 Approved "Endoplasmic reticulum,Cytosol" Cytosol "Endoplasmic reticulum" "HPA068342: " "unprognostic (2.50e-1)" "unprognostic (2.10e-1)" "unprognostic (1.76e-1)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (5.33e-3)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (5.40e-2)" "unprognostic (3.67e-2)" "unprognostic (2.81e-1)" "unprognostic (1.05e-12)" "unprognostic (1.04e-1)" "unprognostic (1.47e-1)" "unprognostic (2.44e-1)" "unprognostic (5.00e-3)" 0.0 0.1 0.4 0.2 1.0 0.0 0.1 0.7 0.8 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.2 12.3 0.0 0.6 0.0 0.0 0.5 0.4 0.0 0.1 0.5 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 9.9 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 2.9 0.0 0.3 0.3 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.1 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 TRAF2 "RNF117, TRAP3" ENSG00000127191 "TNF receptor associated factor 2" Q12933 9 136881912-136926607 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004603, HPA009972, HPA010634" Uncertain Enhanced Cytosol Cytosol "CAB004603: AB_628389, HPA009972: AB_1080350, HPA010634: AB_1080347" "unprognostic (7.77e-2)" "unprognostic (4.54e-3)" "prognostic unfavourable (9.32e-4)" "unprognostic (1.15e-1)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "prognostic unfavourable (3.06e-4)" "unprognostic (4.91e-2)" "unprognostic (7.23e-2)" "unprognostic (4.28e-2)" "unprognostic (7.39e-2)" "unprognostic (2.82e-2)" "prognostic unfavourable (2.09e-4)" "unprognostic (1.80e-3)" "unprognostic (5.52e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-2)" 7.3 6.6 8.7 20.3 10.4 15.9 8.6 16.0 10.0 7.3 8.7 7.4 7.3 11.1 12.3 6.9 12.3 9.0 8.3 8.3 7.5 6.5 8.5 12.3 11.5 19.7 11.2 8.3 6.8 13.9 5.9 8.8 12.1 8.1 10.2 6.2 7.5 13.0 10.1 6.4 13.0 10.4 10.6 8.2 13.8 10.7 13.7 6.4 16.4 14.7 5.2 15.9 8.4 37.5 12.6 11.5 6.7 8.3 10.1 17.4 6.2 10.6 32.9 8.9 7.9 2.5 4.0 17.4 8.8 4.9 12.9 8.8 20.3 19.3 13.3 11.5 5.5 28.1 12.2 14.4 5.3 20.2 9.9 10.0 29.7 12.6 3.7 9.8 10.4 3.0 4.4 10.5 6.0 6.0 16.8 15.2 5.7 15.5 15.9 14.1 14.5 14.8 15.1 13.7 18.1 7.9 8.4 14.6 6.8 11.0 25.8 10.0 18.5 11.6 6.8 16.9 10.9 11.0 14.7 6.3 10.3 13.2 6.0 8.1 12.4 1.3 3.7 6.7 10.4 4.2 14.6 12.6 11.1 13.0 4.9 10.0 9.1 10.9 3.3 10.1 8.3 11.5 17.4 6.2 8.7 10.4 16.0 10.0 7.5 6.5 11.2 8.3 8.1 6.4 TRAF3 "CAP-1, CD40bp, CRAF1, LAP1, RNF118" ENSG00000131323 "TNF receptor associated factor 3" Q13114 14 102777476-102911500 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Immunity, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002933 Uncertain "HPA002933: AB_1080352" "unprognostic (4.06e-2)" "unprognostic (1.75e-2)" "unprognostic (2.08e-2)" "unprognostic (4.49e-3)" "unprognostic (5.25e-2)" "unprognostic (4.17e-2)" "prognostic unfavourable (1.02e-5)" "unprognostic (1.31e-1)" "unprognostic (7.24e-2)" "unprognostic (1.16e-1)" "prognostic favourable (2.42e-5)" "unprognostic (1.29e-1)" "unprognostic (2.29e-2)" "unprognostic (1.28e-1)" "unprognostic (1.71e-1)" "unprognostic (3.13e-2)" "unprognostic (2.12e-1)" 7.6 5.3 13.6 23.3 9.1 18.8 7.7 12.5 16.0 4.2 8.9 8.8 5.8 8.4 7.5 3.9 7.5 8.9 7.1 7.3 16.6 12.7 6.7 7.0 8.1 26.0 11.5 8.0 4.8 5.1 10.0 10.3 6.8 8.5 6.1 8.0 7.9 5.7 8.0 5.5 7.9 11.8 7.8 9.8 14.2 7.1 12.2 6.6 10.5 7.5 4.1 25.4 11.1 9.3 12.0 6.7 4.3 5.7 2.4 5.1 4.9 11.9 13.6 7.6 4.7 4.4 6.3 11.5 9.4 10.3 10.1 8.5 6.6 17.8 9.5 11.7 10.0 7.3 10.8 10.3 10.4 23.7 7.0 8.9 6.0 4.9 7.2 10.1 26.7 6.3 7.8 7.0 10.1 7.3 9.1 28.4 6.4 12.1 21.6 5.9 4.0 10.3 11.9 10.5 4.8 9.0 14.7 20.2 7.2 10.2 7.1 6.6 6.8 11.5 15.5 9.6 7.4 24.9 13.3 20.6 23.5 17.4 10.4 5.2 11.3 2.6 5.7 1.7 3.7 4.6 3.0 12.0 5.1 3.3 4.1 11.5 3.7 2.6 4.3 2.4 2.8 6.7 4.4 4.9 13.6 9.1 12.5 16.0 16.6 12.7 11.5 8.0 8.5 6.6 TRAF6 RNF85 ENSG00000175104 "TNF receptor associated factor 6" Q9Y4K3 11 36487027-36510272 "Enzymes, Predicted intracellular proteins" "DNA damage, Immunity, Osteogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004605, HPA019805, HPA020599" Approved Supported Nucleoli,Mitochondria Mitochondria Nucleoli "CAB004605: AB_628391, HPA019805: AB_1858231, HPA020599: AB_1858232" "unprognostic (2.48e-2)" "unprognostic (1.38e-1)" "unprognostic (2.83e-1)" "unprognostic (8.73e-2)" "unprognostic (1.71e-1)" "unprognostic (1.55e-1)" "unprognostic (2.43e-1)" "unprognostic (2.10e-1)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" "unprognostic (1.16e-2)" "unprognostic (9.22e-2)" "prognostic favourable (1.36e-4)" "unprognostic (2.82e-2)" "unprognostic (1.20e-1)" "unprognostic (3.92e-2)" "unprognostic (1.07e-1)" 13.0 11.0 12.9 8.5 17.0 31.8 11.9 18.1 15.0 10.6 10.7 13.6 8.2 9.5 12.9 9.8 12.4 11.5 9.4 13.9 9.8 7.1 11.2 12.3 15.2 9.2 14.8 10.6 14.6 11.3 11.0 11.9 10.3 12.7 9.6 10.5 10.5 11.0 9.3 13.9 12.7 12.5 12.1 10.1 13.0 10.3 15.0 12.8 18.5 15.6 6.7 10.8 11.3 13.0 10.6 7.7 27.7 11.4 9.6 13.1 8.5 5.1 6.5 12.6 7.1 11.9 8.7 5.5 7.8 8.4 7.2 9.5 5.7 3.5 6.8 4.8 8.2 9.7 10.0 7.9 12.0 11.1 11.7 6.5 5.1 5.1 7.7 7.2 8.0 8.1 11.1 3.9 11.8 10.1 9.7 7.4 9.0 6.3 11.5 3.9 6.8 6.0 7.6 17.1 3.8 8.7 10.7 2.1 11.1 7.8 7.6 5.5 8.7 7.0 8.0 10.3 9.1 9.4 9.4 8.7 7.3 7.3 5.8 5.2 7.7 27.7 8.0 20.9 11.9 11.4 11.7 10.6 10.3 11.6 7.7 8.1 10.0 13.1 11.1 9.6 8.2 4.5 8.0 8.5 12.9 17.0 18.1 15.0 9.8 7.1 14.8 10.6 12.7 12.8 TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041229 Approved Supported "Vesicles,Plasma membrane" Vesicles "Plasma membrane" "HPA041229: AB_10794194" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (2.77e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (9.23e-2)" "unprognostic (6.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.43e-1)" "unprognostic (8.48e-2)" 16.0 18.2 18.3 22.3 20.6 28.5 39.1 28.7 25.6 22.1 29.4 9.1 21.1 37.3 20.4 18.3 32.9 21.9 36.9 21.0 18.3 14.8 21.3 47.3 18.3 40.9 13.4 14.7 19.3 41.6 17.7 20.3 19.5 12.8 16.2 16.9 13.0 24.4 23.1 25.5 32.2 37.8 28.8 14.1 21.4 25.1 13.2 10.6 26.1 20.3 30.9 21.9 21.9 28.9 6.7 12.3 7.7 13.9 3.0 7.1 5.2 20.8 26.7 15.3 27.3 15.8 30.0 18.0 16.1 20.3 19.0 17.1 32.4 27.0 13.4 19.1 20.5 24.5 14.3 28.6 7.2 21.1 18.3 19.1 35.6 24.8 21.0 20.3 27.7 29.6 23.9 18.3 24.0 36.7 20.3 18.1 18.0 47.7 20.8 23.6 30.0 13.1 38.9 25.4 26.8 15.3 11.2 30.8 25.6 13.5 25.9 17.6 29.4 25.0 27.6 23.1 32.5 21.5 17.5 26.2 19.4 17.7 13.2 13.2 17.9 3.7 10.0 7.7 5.4 13.9 5.0 6.7 5.3 5.7 12.3 4.9 3.8 4.5 6.9 3.0 9.4 6.0 7.1 5.2 18.3 20.6 28.7 25.6 18.3 14.8 13.4 14.7 12.8 10.6 TRAIP "RNF206, TRIP" ENSG00000183763 "TRAF interacting protein" Q9BWF2 3 49828599-49856574 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036261, HPA036262" Enhanced Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA036261: AB_10673348, HPA036262: AB_2675029" "unprognostic (5.30e-3)" "unprognostic (9.41e-2)" "unprognostic (1.48e-1)" "unprognostic (6.50e-3)" "unprognostic (1.88e-1)" "unprognostic (7.68e-3)" "prognostic unfavourable (8.77e-5)" "unprognostic (4.61e-2)" "unprognostic (1.52e-2)" "unprognostic (8.61e-2)" "unprognostic (1.24e-2)" "unprognostic (7.97e-2)" "unprognostic (9.01e-5)" "unprognostic (5.84e-2)" "unprognostic (4.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" 4.8 1.6 3.4 6.0 10.7 9.5 3.0 7.4 3.0 3.5 3.7 2.0 3.2 2.3 3.8 2.4 4.5 3.0 2.9 1.5 2.7 2.7 1.6 1.2 1.3 8.1 2.0 2.8 3.4 1.6 1.6 2.0 2.5 3.0 2.9 4.8 2.7 3.1 1.7 2.8 6.7 3.4 3.4 5.1 3.7 1.9 25.0 3.4 11.5 2.2 3.1 6.8 1.9 3.0 5.1 1.6 0.6 3.0 2.7 4.9 1.6 6.4 7.9 11.3 11.3 1.0 1.6 9.3 7.8 3.7 16.5 15.8 9.5 7.4 15.9 5.5 4.5 8.5 11.8 8.9 12.4 9.1 7.8 11.9 9.6 8.5 0.4 9.7 10.0 1.1 1.3 13.2 7.0 4.3 8.6 11.5 7.3 9.3 16.1 12.4 9.0 13.0 8.9 7.6 9.2 3.0 9.0 5.5 9.4 8.6 7.3 5.5 6.6 13.9 3.3 10.6 12.6 14.5 15.2 8.5 20.2 17.0 5.3 13.2 9.4 0.0 1.5 0.6 2.3 0.8 2.0 5.1 1.3 4.9 1.3 3.8 1.7 2.6 0.3 2.7 3.0 1.6 0.8 1.6 3.4 10.7 7.4 3.0 2.7 2.7 2.0 2.8 3.0 3.4 TRDMT1 "DNMT2, RNMT1" ENSG00000107614 "TRNA aspartic acid methyltransferase 1" O14717 10 17142254-17202054 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009468, HPA036945, HPA036946" Approved Approved Nucleoplasm,Nucleoli,Centrosome Nucleoli "Nucleoplasm, Centrosome" "CAB009468: AB_2208432, HPA036945: , HPA036946: " "unprognostic (4.55e-1)" "unprognostic (3.22e-2)" "unprognostic (4.49e-6)" "unprognostic (7.07e-2)" "unprognostic (3.87e-3)" "unprognostic (1.33e-1)" "unprognostic (3.27e-4)" "unprognostic (3.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "unprognostic (2.65e-2)" "unprognostic (3.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.60e-1)" "unprognostic (1.40e-1)" "unprognostic (2.64e-2)" 6.1 4.4 4.4 8.5 7.7 4.0 6.3 14.0 6.2 5.3 3.8 4.2 4.7 4.1 7.5 14.4 3.9 6.8 5.1 5.0 4.9 4.5 6.7 2.7 5.3 5.3 4.3 2.9 9.6 5.0 12.8 12.6 5.1 6.2 5.0 3.6 8.0 5.6 3.8 4.3 4.4 5.0 5.4 5.1 5.9 4.2 4.2 6.1 19.9 11.5 3.3 5.7 4.0 5.2 6.1 10.5 5.2 4.4 3.5 8.0 3.6 5.1 2.5 10.0 2.6 3.8 2.2 0.0 4.4 3.2 4.7 5.5 4.2 4.3 3.5 0.6 5.0 2.6 6.7 4.2 5.4 7.4 4.3 5.2 3.8 2.5 3.4 3.4 3.9 3.0 2.6 3.2 2.3 6.1 6.5 3.9 7.7 1.6 17.0 0.8 6.3 2.9 3.7 7.8 2.2 2.5 2.8 2.7 3.4 0.0 1.9 3.4 4.8 3.1 3.6 3.4 7.2 6.3 5.1 5.0 4.7 8.9 4.3 4.8 3.4 5.2 4.4 2.4 3.9 2.5 7.2 5.4 6.6 4.9 5.5 6.1 8.0 5.8 2.8 3.5 1.4 10.5 2.2 3.6 4.4 7.7 14.0 6.2 4.9 4.5 4.3 2.9 6.2 6.1 TREH "MGC129621, TRE, TREA" ENSG00000118094 Trehalase O43280 11 118657316-118679690 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 51.8" "Cell line enhanced" "Detected in some" "BEWO: 5.3;Hep G2: 2.1;RPMI-8226: 1.9;SiHa: 1.8;U-2 OS: 2.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039913, HPA042045" Enhanced "Intracellular and membrane" 12000000 "HPA039913: AB_10674988, HPA042045: AB_2677817" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (1.01e-2)" "unprognostic (5.22e-4)" "unprognostic (2.52e-1)" "unprognostic (9.83e-2)" "prognostic favourable (3.76e-4)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (1.63e-2)" "prognostic favourable (2.33e-6)" "unprognostic (2.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.1 24.1 0.0 0.0 28.9 0.1 3.3 0.6 0.1 3.7 0.1 0.1 0.1 6.1 2.6 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.2 0.4 0.0 0.2 0.0 0.1 0.1 51.8 0.0 0.1 0.1 0.6 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.3 5.3 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 1.9 0.0 0.0 0.2 0.9 1.8 0.2 1.4 0.7 0.0 0.8 0.1 2.5 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.0 TREX1 "AGS1, DRN3" ENSG00000213689 "Three prime repair exonuclease 1" Q9NSU2 3 48465811-48467645 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Exonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease mutation, Neurodegeneration, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 31.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035437, HPA046721" Supported Supported Cytosol Cytosol "HPA035437: AB_10672092, HPA046721: " 14.2 14.3 16.7 14.6 10.6 20.7 17.2 13.0 16.9 13.4 11.0 12.8 17.5 10.3 8.1 14.9 16.6 14.5 12.3 9.8 14.4 14.2 11.6 12.7 12.5 26.2 14.6 17.4 7.3 13.0 6.8 31.2 11.6 11.2 15.4 9.3 10.8 32.2 19.3 10.8 22.9 10.9 8.2 12.6 25.5 12.4 4.6 10.1 18.5 7.4 18.3 21.7 13.3 10.6 24.9 35.5 23.3 41.8 8.6 13.1 20.1 8.0 7.4 6.2 4.4 7.7 7.9 0.0 2.6 13.1 22.0 31.0 0.1 9.6 9.5 5.4 11.1 9.4 0.4 11.8 3.1 8.0 0.7 5.5 26.6 0.4 9.7 5.0 3.9 6.9 1.1 11.1 4.4 9.3 0.0 14.6 9.3 0.1 7.0 3.6 0.0 4.6 5.8 1.6 18.6 5.8 1.6 0.0 3.7 9.6 13.0 6.3 0.4 8.4 9.8 4.1 3.9 8.7 6.1 11.8 6.8 4.0 9.1 10.7 3.3 2.1 41.8 3.0 9.8 32.5 5.6 24.6 13.1 9.4 35.5 24.9 12.4 10.3 23.3 8.6 24.3 28.0 11.6 20.1 16.7 10.6 13.0 16.9 14.4 14.2 14.6 17.4 11.2 10.1 TREX2 ENSG00000183479 "Three prime repair exonuclease 2" Q9BQ50 X 153444720-153470587 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 39.6" "Cell line enhanced" "Detected in many" "HEK 293: 7.4;U-698: 10.1;U-937: 9.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.9;eosinophil: 5.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 5.7" "Not detected" "Not detected" HPA054060 Uncertain "HPA054060: " "unprognostic (2.32e-2)" "unprognostic (2.05e-3)" "unprognostic (1.13e-3)" "unprognostic (7.18e-4)" "unprognostic (6.05e-2)" "unprognostic (1.81e-2)" "unprognostic (8.40e-2)" "unprognostic (2.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (1.52e-1)" "unprognostic (9.34e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-2)" 3.2 1.5 2.1 3.4 3.0 1.9 2.1 1.1 3.6 4.3 2.6 1.9 15.5 1.4 2.5 2.2 4.5 2.6 2.2 3.5 1.6 1.2 2.8 4.6 2.4 3.1 2.4 2.4 2.1 2.2 1.5 1.7 2.6 2.7 2.5 1.4 1.4 4.5 7.4 2.0 39.6 2.3 1.9 1.2 4.3 1.7 2.1 1.9 5.8 3.3 6.2 4.7 2.2 5.2 0.4 0.3 5.7 0.1 0.2 0.4 0.2 2.8 3.5 0.3 1.3 0.5 0.7 0.3 0.9 0.8 0.7 2.0 1.0 0.7 0.3 1.8 0.8 3.1 1.2 2.0 0.0 3.1 7.4 0.3 0.7 0.4 0.3 0.8 1.9 0.8 1.8 0.8 0.7 0.3 0.4 3.5 0.2 3.3 2.0 2.2 1.1 2.4 4.8 1.0 2.2 0.3 1.0 0.8 0.4 0.3 0.3 1.0 0.5 0.9 0.0 1.3 2.3 2.8 1.0 3.9 2.7 10.1 0.3 9.4 1.5 3.9 0.0 5.7 0.3 0.0 0.2 0.4 0.1 0.3 0.3 0.3 0.4 0.1 0.0 0.2 0.1 0.0 0.1 0.2 2.1 3.0 1.1 3.6 1.6 1.2 2.4 2.4 2.7 1.9 TRIB1 "C8FW, GIG2, TRB1" ENSG00000173334 "Tribbles pseudokinase 1" Q96RU8 8 125430321-125438405 "Enzymes, Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.2;thyroid gland: 90.7" "Cell line enhanced" "Detected in many" "HEL: 54.0;U-266/70: 33.1;U-266/84: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 10.8;neutrophil: 5.8;non-classical monocyte: 3.7;T-reg: 3.1" "Group enriched" "Detected in many" 11 "granulocytes: 10.8;monocytes: 3.7;T-cells: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063982 Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA063982: " "unprognostic (1.90e-3)" "unprognostic (1.45e-1)" "unprognostic (8.80e-3)" "unprognostic (1.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.57e-2)" "unprognostic (4.12e-2)" "unprognostic (1.62e-2)" "unprognostic (6.81e-3)" "unprognostic (9.36e-2)" "unprognostic (2.97e-3)" "unprognostic (1.94e-1)" "unprognostic (1.04e-2)" "unprognostic (5.55e-2)" "unprognostic (2.08e-2)" 26.7 6.5 5.9 17.6 6.5 84.2 13.3 4.3 6.1 10.4 12.4 4.4 6.6 4.9 6.2 6.7 10.9 10.9 21.0 11.1 4.3 4.0 16.6 63.5 28.9 14.6 4.2 3.9 6.4 23.6 20.9 7.2 15.5 4.5 12.1 13.3 15.0 14.5 9.1 22.3 10.4 16.9 11.3 3.1 15.9 18.5 5.6 3.1 9.2 90.7 17.6 12.1 12.4 9.0 0.2 0.5 10.8 3.7 0.0 3.1 0.1 4.0 4.6 0.6 1.3 1.3 2.6 7.3 2.6 3.7 1.9 0.6 6.2 5.4 7.4 2.5 1.9 3.1 2.0 2.6 1.7 3.2 9.7 54.0 2.0 12.0 3.4 27.0 4.9 2.5 3.9 8.1 18.4 5.7 4.7 23.5 0.2 4.3 2.5 4.2 4.5 9.0 5.1 0.9 8.0 15.9 15.5 3.9 1.4 6.5 7.1 25.7 1.8 1.3 2.9 2.1 2.8 2.1 3.3 33.1 33.0 10.3 3.8 0.1 5.0 0.0 0.9 10.8 0.0 1.2 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 5.8 0.0 3.7 0.3 3.1 0.1 5.9 6.5 4.3 6.1 4.3 4.0 4.2 3.9 4.5 3.1 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 40.2;HEL: 39.4;K-562: 53.6;SK-MEL-30: 39.1;WM-115: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 24.8" "Group enriched" "Detected in many" 9 "B-cells: 7.1;NK-cells: 9.5;T-cells: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 19.6 30.9 13.2 17.7 13.3 7.0 23.2 23.2 23.0 10.8 12.3 10.5 6.7 8.7 23.0 22.6 8.1 11.6 14.5 18.2 15.0 10.8 24.8 10.6 18.9 33.0 13.4 16.2 52.3 14.4 6.6 11.3 23.0 15.5 16.3 6.9 35.7 9.9 13.6 6.9 8.2 11.9 17.6 10.4 38.9 19.5 13.9 10.1 37.3 12.1 6.2 33.4 21.9 23.2 7.1 0.6 1.5 0.1 9.5 24.8 4.5 0.0 0.0 30.6 40.2 11.0 10.2 0.0 1.7 1.6 1.0 1.7 0.1 3.3 3.4 1.2 3.6 0.5 2.2 3.4 0.9 3.8 6.3 39.4 0.1 0.5 13.7 2.2 15.1 9.4 3.5 4.4 1.2 4.8 53.6 0.0 1.7 0.3 5.0 9.4 14.5 3.9 0.0 10.2 1.4 7.0 5.0 26.4 12.6 0.2 1.6 39.1 0.0 0.2 3.0 14.6 7.3 0.1 3.8 0.0 0.0 4.9 7.8 7.7 53.8 0.8 0.1 1.5 7.3 0.0 8.8 5.3 14.4 7.7 0.6 7.1 8.5 5.2 0.3 9.5 0.1 0.0 24.8 4.5 13.2 13.3 23.2 23.0 15.0 10.8 13.4 16.2 15.5 10.1 TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 39.0;salivary gland: 47.5" "Cell line enhanced" "Detected in many" "HHSteC: 87.0;hTCEpi: 53.9;hTERT-HME1: 62.7;SK-MEL-30: 79.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm Nucleoplasm "HPA015272: AB_1858269, HPA055442: " "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.25e-3)" "unprognostic (1.92e-1)" "prognostic unfavourable (1.70e-4)" "prognostic unfavourable (6.75e-5)" "unprognostic (1.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "prognostic unfavourable (2.07e-13)" "unprognostic (7.62e-2)" "unprognostic (2.79e-2)" "unprognostic (2.31e-1)" "unprognostic (4.05e-3)" 4.8 8.7 1.6 2.8 1.5 9.7 6.0 3.8 4.2 2.5 1.8 1.2 3.6 1.0 2.1 3.1 9.8 1.1 2.7 3.0 1.4 2.0 3.3 39.0 8.2 7.3 1.0 2.4 4.4 13.8 2.0 10.5 6.2 1.6 3.9 1.6 3.7 47.5 5.3 1.5 6.5 2.5 1.3 0.7 7.9 4.4 2.7 0.6 6.7 27.2 4.1 7.0 2.7 5.3 15.5 4.7 3.3 4.4 6.6 11.4 5.1 10.9 5.5 0.7 1.6 1.9 2.5 4.7 3.2 8.7 3.1 6.5 11.5 5.4 4.7 3.2 2.9 8.8 3.0 14.6 2.9 1.7 2.1 3.6 1.2 18.7 87.0 9.2 1.8 10.1 53.9 5.8 62.7 6.0 12.6 21.3 0.3 10.1 0.5 11.2 1.6 18.1 2.1 0.9 10.1 3.6 4.4 2.0 3.2 0.7 26.5 79.1 7.7 24.5 3.4 1.7 2.9 0.0 5.0 7.4 9.5 8.4 1.4 8.1 6.0 2.5 4.4 1.0 10.0 3.4 7.1 15.5 9.3 11.4 4.7 10.2 10.7 7.6 3.3 6.6 1.7 2.1 6.4 5.1 1.6 1.5 3.8 4.2 1.4 2.0 1.0 2.4 1.6 0.6 TRIM11 "BIA1, RNF92" ENSG00000154370 "Tripartite motif containing 11" Q96F44 1 228393673-228406840 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028541, HPA043879" Approved Enhanced Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA028541: AB_10600833, HPA043879: " "unprognostic (1.73e-1)" "unprognostic (9.73e-3)" "unprognostic (5.48e-3)" "unprognostic (7.73e-2)" "unprognostic (3.27e-1)" "unprognostic (2.33e-1)" "prognostic unfavourable (7.42e-5)" "unprognostic (1.08e-1)" "unprognostic (9.74e-2)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "prognostic unfavourable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.89e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" 8.8 9.2 8.9 13.8 16.5 33.2 23.8 45.2 11.5 8.7 11.2 6.4 15.1 10.1 8.7 10.6 13.3 9.4 13.9 6.9 9.2 8.5 7.7 7.1 27.5 18.6 9.0 8.0 9.0 11.9 8.5 7.2 9.4 7.1 10.5 9.7 6.0 14.4 18.2 5.0 12.5 11.8 8.6 6.0 16.5 12.6 9.5 7.8 20.0 9.0 9.7 13.1 9.5 24.3 6.4 6.9 10.0 11.4 9.4 11.8 5.4 13.8 13.2 7.1 9.7 5.3 4.4 33.5 9.1 6.1 10.6 8.5 16.0 12.1 10.4 10.2 6.1 22.6 8.5 8.7 4.5 11.6 20.5 8.6 12.2 8.6 14.5 10.9 13.2 5.9 14.0 10.9 5.5 5.2 19.7 13.5 5.4 9.0 13.1 17.2 18.1 11.7 12.9 6.4 12.6 6.9 17.0 11.8 21.7 7.6 21.6 12.0 15.2 18.2 5.8 6.7 9.5 15.7 18.8 13.9 9.2 9.2 8.4 8.7 10.6 6.1 6.9 8.3 9.6 8.2 10.2 5.8 10.7 11.8 6.9 6.4 6.3 8.4 10.0 9.4 11.4 5.5 9.8 5.4 8.9 16.5 45.2 11.5 9.2 8.5 9.0 8.0 7.1 7.8 TRIM13 "DLEU5, Leu5, RFP2, RNF77" ENSG00000204977 "Tripartite motif containing 13" O60858 13 49995888-50020481 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000367 Enhanced "HPA000367: AB_1856196" "unprognostic (1.14e-1)" "unprognostic (8.22e-2)" "unprognostic (6.14e-2)" "unprognostic (2.23e-3)" "unprognostic (4.75e-3)" "unprognostic (5.01e-2)" "unprognostic (4.60e-2)" "unprognostic (2.83e-2)" "unprognostic (2.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.44e-1)" "unprognostic (5.07e-1)" "unprognostic (7.28e-3)" "unprognostic (4.66e-2)" "unprognostic (9.01e-2)" "unprognostic (2.37e-2)" "unprognostic (1.55e-2)" 13.2 9.8 9.9 11.9 11.4 37.5 19.6 18.5 13.5 13.1 11.7 12.3 15.2 8.6 13.9 10.7 18.8 12.2 8.7 12.4 10.1 9.2 16.6 9.9 14.7 12.4 12.2 8.0 13.8 14.0 10.8 14.4 10.0 11.5 14.5 14.0 9.6 16.2 15.6 16.3 18.2 13.0 10.4 10.8 15.3 10.6 49.0 12.1 25.1 17.3 13.9 15.5 13.0 12.9 28.4 20.6 21.6 13.0 15.4 17.2 8.4 5.1 6.0 20.9 16.1 11.8 18.5 9.5 8.5 12.3 6.9 4.8 8.3 11.8 19.1 2.6 9.2 8.1 9.2 11.2 8.5 7.3 8.1 18.9 4.6 9.2 13.2 18.1 11.1 13.5 16.5 6.3 10.5 15.2 10.0 6.1 13.5 4.6 15.0 28.4 18.9 4.5 18.3 0.9 5.7 14.6 8.5 8.4 13.8 7.7 8.0 11.8 9.0 23.0 14.1 7.1 6.6 5.8 4.7 4.4 3.6 14.0 3.2 8.3 9.6 12.1 10.8 16.1 12.2 9.3 15.3 28.2 16.5 15.9 13.5 28.4 14.6 13.6 21.6 15.4 13.0 20.6 17.2 8.4 9.9 11.4 18.5 13.5 10.1 9.2 12.2 8.0 11.5 12.1 TRIM17 "RBCC, RNF16, terf" ENSG00000162931 "Tripartite motif containing 17" Q9Y577 1 228407940-228416861 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8;testis: 18.3" "Cell line enhanced" "Detected in some" "BEWO: 7.6;HEL: 3.5;NTERA-2: 3.2;SH-SY5Y: 4.0;T-47d: 9.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054908 Uncertain Approved Vesicles Vesicles "HPA054908: " "prognostic favourable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (3.06e-2)" "unprognostic (5.45e-2)" "unprognostic (1.25e-1)" "unprognostic (7.74e-3)" "unprognostic (7.42e-3)" "unprognostic (2.02e-1)" "unprognostic (1.17e-2)" "unprognostic (8.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.04e-1)" "unprognostic (5.96e-4)" "unprognostic (3.88e-1)" "unprognostic (4.88e-2)" "unprognostic (6.33e-2)" "unprognostic (3.64e-1)" 1.3 0.8 14.4 1.5 19.1 1.1 1.9 25.8 11.8 1.5 0.9 0.6 1.7 1.4 3.6 1.7 1.3 3.9 1.7 1.5 8.9 3.4 1.2 0.6 1.7 2.0 0.7 9.2 2.2 1.1 0.8 1.0 1.3 2.7 2.0 0.8 1.9 5.9 3.8 0.8 3.5 1.6 1.1 0.9 5.3 1.4 18.3 4.7 0.0 2.9 0.1 1.2 2.5 1.3 1.7 0.6 0.7 0.3 0.0 1.0 0.1 0.3 0.6 0.4 0.4 0.0 0.0 7.6 0.5 0.0 0.0 0.1 1.7 0.9 0.1 1.9 0.0 1.7 0.0 0.0 0.1 0.3 0.7 3.5 1.0 0.2 1.6 0.1 0.3 0.2 0.2 0.1 0.0 0.0 0.2 0.5 0.1 0.1 0.3 0.0 3.2 0.2 0.1 0.1 0.0 0.0 0.8 0.5 4.0 0.0 0.4 0.0 9.4 0.2 0.0 0.3 1.7 0.3 0.1 0.1 0.0 0.2 0.2 0.1 0.3 0.0 0.3 0.7 0.9 0.1 1.0 0.6 0.2 1.0 0.0 1.7 1.0 0.8 0.2 0.0 0.2 0.6 0.0 0.1 14.4 19.1 25.8 11.8 8.9 3.4 0.7 9.2 2.7 4.7 TRIM2 "CMT2R, KIAA0517, RNF86" ENSG00000109654 "Tripartite motif containing 2" Q9C040 4 153152342-153339320 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.0" "Cell line enhanced" "Detected in many" "AF22: 28.1;NTERA-2: 23.1;RPTEC TERT1: 26.3;SK-MEL-30: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "memory CD4 T-cell: 5.4" "Group enriched" "Detected in many" 4 "B-cells: 1.9;T-cells: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035853, HPA035854" Enhanced Approved Centrosome Centrosome "HPA035853: AB_10669533, HPA035854: AB_10669659" "unprognostic (8.94e-2)" "unprognostic (7.89e-2)" "unprognostic (6.21e-3)" "unprognostic (7.51e-3)" "unprognostic (2.07e-2)" "unprognostic (2.32e-1)" "unprognostic (1.16e-2)" "unprognostic (2.30e-3)" "unprognostic (5.30e-2)" "unprognostic (6.77e-2)" "unprognostic (1.93e-2)" "unprognostic (1.42e-2)" "prognostic favourable (6.58e-14)" "unprognostic (5.89e-2)" "unprognostic (1.17e-2)" "unprognostic (4.19e-2)" "unprognostic (4.13e-2)" 4.2 9.9 28.4 4.4 35.7 0.6 12.2 28.9 56.9 19.6 17.8 67.0 5.9 13.5 9.7 15.1 8.5 12.9 10.3 6.2 38.9 25.3 22.1 6.4 5.9 2.3 39.4 34.6 10.9 8.2 1.0 10.9 2.5 45.3 11.5 19.2 4.6 30.1 11.8 1.8 3.8 14.4 6.6 44.2 8.8 23.5 1.9 44.7 0.0 38.9 0.6 4.3 7.6 5.5 1.9 0.8 0.3 0.6 0.3 5.4 0.7 4.7 0.2 28.1 12.3 10.6 12.2 0.4 6.3 8.6 1.8 2.6 2.7 0.3 0.2 4.0 10.9 4.3 13.1 2.4 1.8 0.1 4.9 0.2 2.9 0.6 12.4 0.2 0.1 7.9 1.4 3.6 2.3 1.6 0.2 0.1 2.2 0.4 1.3 0.0 23.1 5.6 0.8 5.1 0.0 26.3 6.2 9.1 17.9 3.0 11.4 25.2 1.2 0.2 2.4 7.9 2.3 6.1 3.0 0.1 0.0 0.1 11.8 0.1 9.7 0.3 0.6 0.1 0.1 0.0 0.0 1.6 5.4 0.1 0.8 1.9 1.6 1.0 0.2 0.3 0.0 0.1 2.6 0.7 28.4 35.7 28.9 41.1 38.9 25.3 39.4 34.6 45.3 44.7 TRIM21 "RNF81, Ro/SSA, RO52, SSA1" ENSG00000132109 "Tripartite motif containing 21" P19474 11 4384897-4393696 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "DNA-binding, Ribonucleoprotein, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 72.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004566, HPA005673" Approved Approved Nucleoplasm Nucleoplasm "CAB004566: AB_628286, HPA005673: AB_1080090" "prognostic favourable (4.83e-5)" "unprognostic (4.55e-2)" "unprognostic (3.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.50e-1)" "unprognostic (1.43e-1)" "prognostic unfavourable (1.87e-4)" "unprognostic (1.20e-1)" "unprognostic (5.04e-2)" "unprognostic (1.27e-1)" "unprognostic (2.49e-2)" "unprognostic (3.31e-1)" "unprognostic (1.82e-2)" "unprognostic (6.27e-2)" "unprognostic (4.69e-2)" "prognostic favourable (2.26e-6)" "unprognostic (9.12e-3)" 18.2 12.1 4.9 13.7 6.5 15.0 9.8 2.5 6.4 15.0 11.7 6.4 6.0 12.5 11.6 10.3 14.6 10.4 10.8 8.5 5.0 5.3 12.9 14.9 14.6 21.4 6.8 4.0 17.4 10.7 4.3 9.9 19.9 8.6 18.0 12.0 8.5 11.9 8.6 4.5 6.9 21.8 12.0 4.7 28.3 13.5 6.0 4.7 21.5 19.1 6.8 17.0 11.6 13.5 10.9 22.0 72.4 27.5 14.5 19.5 28.6 5.9 7.0 3.5 3.3 7.3 11.0 4.9 7.6 14.4 30.2 33.5 3.2 17.2 9.1 3.5 11.2 8.5 6.2 11.6 9.4 15.2 6.9 14.0 4.0 2.8 16.2 16.5 13.9 10.7 7.0 6.1 4.2 18.4 4.4 10.0 10.0 5.2 8.6 12.1 3.0 3.6 6.1 4.6 5.0 11.9 5.5 0.0 1.5 6.2 7.0 8.4 2.4 11.3 16.5 7.4 5.8 3.8 2.8 5.3 4.1 5.8 6.6 13.1 5.2 18.8 26.9 60.1 19.3 27.5 16.8 10.5 16.6 17.1 22.0 10.9 14.9 15.7 72.4 14.5 24.4 7.4 19.5 28.6 4.9 6.5 2.5 6.4 5.0 5.3 6.8 4.0 8.6 4.7 TRIM22 "GPSTAF50, RNF94, STAF50" ENSG00000132274 "Tripartite motif containing 22" Q8IYM9 11 5689689-5737089 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.3;BJ hTERT+ SV40 Large T+ RasG12V: 47.9;HSkMC: 42.0;TIME: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA003307, HPA003575" Approved Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA003307: AB_1080381, HPA003575: AB_1080378" "unprognostic (1.47e-2)" "unprognostic (5.27e-3)" "unprognostic (4.00e-2)" "unprognostic (4.21e-3)" "unprognostic (2.21e-1)" "unprognostic (1.21e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (1.86e-3)" "unprognostic (2.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.98e-2)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" "unprognostic (1.15e-1)" "unprognostic (9.16e-2)" 34.3 6.9 8.8 32.8 13.3 22.2 17.3 3.2 10.3 14.4 12.2 10.6 15.1 6.5 20.0 18.9 17.6 17.2 20.2 12.4 10.3 6.6 13.9 19.3 29.8 62.2 15.5 6.5 21.9 5.6 2.1 8.1 9.4 13.3 20.4 13.7 15.0 17.2 14.6 7.1 7.8 28.7 13.5 22.9 65.4 11.2 6.3 12.0 35.6 15.5 13.4 40.6 19.8 13.5 49.0 55.2 33.0 50.3 18.0 58.1 47.3 0.8 0.2 3.4 0.6 18.5 37.3 1.0 10.9 19.1 20.8 47.9 0.3 2.2 23.0 3.3 15.4 2.3 7.6 11.4 2.0 0.5 0.0 1.3 1.2 0.4 24.3 3.5 2.2 42.0 10.8 4.1 1.9 25.6 0.5 1.2 22.6 0.4 12.0 3.6 9.8 1.2 14.9 0.8 0.5 10.9 3.5 0.4 0.8 1.0 1.0 0.4 1.2 3.9 33.4 12.9 7.0 0.6 0.6 1.3 1.1 2.5 16.2 6.4 1.7 27.4 35.7 23.8 35.8 43.5 47.0 46.5 39.0 37.8 42.8 49.0 35.2 33.7 33.0 18.0 50.3 55.2 58.1 47.3 8.8 13.3 3.2 10.3 10.3 6.6 15.5 6.5 13.3 12.0 TRIM23 "ARD1, ARFD1, RNF46" ENSG00000113595 "Tripartite motif containing 23" P36406 5 65589680-65625975 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039605 Approved "HPA039605: AB_10673146" "unprognostic (4.06e-1)" "unprognostic (1.07e-1)" "unprognostic (5.11e-2)" "unprognostic (3.63e-1)" "unprognostic (7.96e-2)" "unprognostic (1.59e-1)" "unprognostic (1.02e-1)" "unprognostic (5.00e-3)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (3.19e-1)" "unprognostic (3.19e-2)" "unprognostic (1.06e-2)" "unprognostic (2.62e-1)" "unprognostic (6.55e-3)" "unprognostic (2.70e-1)" 8.6 12.7 15.0 6.6 17.9 7.6 9.4 25.8 34.3 11.5 7.8 9.5 7.3 4.5 10.6 7.0 9.0 8.6 6.3 12.3 16.3 15.2 10.2 11.8 6.6 7.7 14.4 18.8 16.2 6.5 11.1 11.6 7.9 22.1 12.9 5.3 4.1 5.7 9.4 14.8 6.6 5.2 9.3 14.2 8.2 5.6 10.9 14.0 7.5 12.4 4.4 7.6 7.5 7.6 6.0 3.8 14.5 4.5 5.6 9.9 4.5 6.3 8.7 9.3 14.0 14.5 14.6 7.0 12.1 11.6 10.4 12.8 8.0 6.1 4.9 14.6 8.5 5.1 9.1 7.1 16.1 5.1 9.6 3.9 11.9 5.0 13.5 2.4 5.5 11.4 6.0 11.6 10.5 5.0 4.5 7.0 12.2 5.9 5.0 2.7 5.1 3.6 4.7 16.9 7.0 5.4 6.5 5.5 7.7 11.6 3.5 9.6 7.6 3.3 8.5 8.1 8.7 10.1 8.9 8.7 8.0 6.0 9.5 4.7 8.1 14.5 4.0 9.5 5.6 3.0 6.9 4.7 6.1 4.9 3.6 6.0 9.9 7.5 10.1 5.6 4.5 3.8 6.9 4.5 15.0 17.9 25.8 31.1 16.3 15.2 14.4 18.8 22.1 14.0 TRIM24 "hTIF1, RNF82, TIF1, Tif1a" ENSG00000122779 "Tripartite motif containing 24" O15164 7 138460334-138589993 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 42.7;HMC-1: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043495, HPA061717" Approved Enhanced Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA043495: AB_10962915, HPA061717: AB_2684592" "unprognostic (2.40e-1)" "unprognostic (9.52e-3)" "unprognostic (2.23e-1)" "unprognostic (3.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "prognostic unfavourable (9.94e-4)" "prognostic favourable (6.57e-4)" "unprognostic (4.01e-2)" "unprognostic (8.93e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (1.62e-1)" "unprognostic (2.25e-2)" "unprognostic (5.54e-2)" "unprognostic (6.34e-2)" 10.3 31.4 10.4 11.2 10.6 8.8 8.8 8.5 10.7 9.4 9.2 14.6 5.7 9.4 9.0 8.5 11.3 7.0 10.3 9.7 8.4 8.5 9.6 21.5 10.7 8.5 10.5 8.0 29.9 11.6 20.7 7.3 13.5 8.4 13.6 9.1 7.5 10.1 7.1 16.0 9.8 14.1 9.4 8.0 8.5 10.8 24.1 11.3 34.8 8.8 9.2 8.9 11.3 11.2 1.3 1.9 3.7 2.5 2.2 2.7 0.8 4.1 5.1 42.7 12.3 2.9 2.6 3.3 3.9 4.1 3.0 3.0 8.1 3.9 8.0 3.9 3.7 2.2 20.7 3.2 4.5 6.1 5.1 17.7 3.8 24.9 3.9 13.7 57.8 2.3 3.4 2.5 4.1 7.2 20.0 4.9 3.6 8.1 23.4 12.5 16.3 4.6 18.6 5.0 6.8 6.8 12.5 8.9 20.2 7.3 6.5 2.1 4.5 9.1 3.0 3.5 2.9 6.2 5.3 4.6 4.9 13.7 5.9 9.1 5.2 1.1 2.3 3.6 2.2 2.5 0.4 0.9 1.9 1.2 1.9 1.3 1.8 2.0 3.7 2.2 1.1 1.4 2.7 0.8 10.4 10.6 8.5 9.7 8.4 8.5 10.5 8.0 8.4 11.3 TRIM25 "EFP, RNF147, ZNF147" ENSG00000121060 "Tripartite motif containing 25" Q14258 17 56887909-56914038 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Ligase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "neutrophil: 20.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 20.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005909 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" 35000 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA005909: AB_1078722" "unprognostic (8.73e-3)" "unprognostic (1.57e-2)" "unprognostic (2.06e-2)" "unprognostic (6.06e-2)" "unprognostic (2.69e-1)" "unprognostic (3.78e-2)" "prognostic unfavourable (9.37e-4)" "unprognostic (1.53e-1)" "unprognostic (4.23e-1)" "unprognostic (1.15e-1)" "prognostic favourable (3.36e-4)" "unprognostic (3.23e-1)" "unprognostic (3.11e-2)" "prognostic favourable (9.35e-4)" "unprognostic (5.21e-2)" "unprognostic (5.13e-2)" "unprognostic (7.39e-2)" 20.0 19.7 7.5 23.6 8.9 32.6 19.3 11.6 7.8 15.3 22.5 5.0 8.0 15.3 13.4 12.6 17.7 15.3 18.4 8.3 5.8 6.3 10.1 27.0 20.8 15.9 6.7 5.5 13.3 15.3 13.6 11.5 55.0 7.4 12.2 14.3 12.5 14.5 11.5 11.7 23.1 20.7 10.1 5.2 35.8 14.1 12.8 6.5 26.2 11.8 15.1 18.5 10.6 35.9 1.7 2.4 20.0 2.3 0.8 1.5 0.7 28.8 14.3 3.5 11.9 26.7 22.6 0.0 11.4 23.1 27.3 23.6 13.9 15.9 28.2 23.7 10.9 17.2 17.2 15.3 15.3 24.0 13.6 18.2 11.1 15.4 23.0 21.7 13.1 10.1 25.8 14.2 30.3 18.1 4.4 17.3 13.8 19.3 24.2 15.7 2.2 27.8 17.4 11.9 17.7 15.9 22.8 6.9 6.4 9.0 14.5 26.5 19.6 17.7 12.0 12.8 9.2 19.6 11.8 9.8 18.7 4.7 12.4 15.0 5.0 3.0 2.3 0.9 0.9 1.9 1.1 1.7 0.8 0.8 2.4 1.4 0.6 0.8 20.0 0.8 1.4 1.7 1.5 0.7 7.5 8.9 11.6 7.8 5.8 6.3 6.7 5.5 7.4 6.5 TRIM26 "RNF95, ZNF173" ENSG00000234127 "Tripartite motif containing 26" Q12899 6 30184455-30213427 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044975, HPA050456" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA044975: , HPA050456: " "unprognostic (1.93e-1)" "unprognostic (5.41e-2)" "unprognostic (8.53e-2)" "unprognostic (1.96e-3)" "unprognostic (1.52e-1)" "unprognostic (5.50e-2)" "unprognostic (2.02e-1)" "unprognostic (1.40e-2)" "unprognostic (2.85e-1)" "unprognostic (3.08e-2)" "unprognostic (1.97e-1)" "unprognostic (7.00e-3)" "unprognostic (1.37e-2)" "unprognostic (1.63e-3)" "unprognostic (5.21e-2)" "unprognostic (8.82e-2)" "prognostic favourable (3.25e-5)" 11.9 12.6 10.6 20.0 12.2 13.8 13.2 17.6 14.9 10.7 16.1 15.9 14.5 18.5 12.9 18.4 21.5 21.1 18.6 8.4 10.8 11.3 19.5 19.2 12.2 21.3 13.1 8.1 10.9 15.3 16.3 11.5 10.8 12.3 13.4 9.8 17.7 18.4 20.6 9.9 21.5 21.9 14.2 13.1 17.6 15.2 10.9 14.0 13.7 15.8 10.7 21.7 14.7 24.6 3.6 3.8 1.7 4.2 2.1 4.1 3.6 10.2 2.2 0.0 14.5 4.8 2.8 4.7 2.8 3.3 7.2 7.2 0.0 0.4 22.9 8.2 7.1 11.7 0.0 10.0 2.3 0.0 6.7 3.5 1.6 8.3 4.5 4.5 2.9 3.0 3.5 7.3 4.6 4.5 1.6 0.0 0.0 0.0 7.5 11.1 0.0 3.9 9.9 6.9 3.3 6.0 9.6 0.4 6.2 10.5 4.6 2.9 3.6 1.5 7.5 5.6 3.9 0.0 0.1 9.2 16.4 12.1 0.0 13.0 8.9 1.7 3.1 0.5 3.9 4.2 3.2 3.2 2.9 3.8 3.8 3.6 1.8 2.7 1.7 2.1 2.6 1.9 4.1 3.6 10.6 12.2 17.6 14.9 10.8 11.3 13.1 8.1 12.3 14.0 TRIM27 "RFP, RNF76" ENSG00000204713 "Tripartite motif containing 27" P14373 6 28903002-28923989 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048684, HPA053408" Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA048684: , HPA053408: " "unprognostic (1.57e-1)" "unprognostic (1.48e-2)" "unprognostic (2.36e-1)" "unprognostic (1.14e-2)" "unprognostic (1.70e-2)" "unprognostic (2.56e-1)" "unprognostic (2.00e-3)" "unprognostic (1.17e-2)" "unprognostic (1.01e-2)" "unprognostic (1.12e-3)" "unprognostic (4.76e-3)" "unprognostic (1.16e-2)" "prognostic unfavourable (3.50e-6)" "unprognostic (1.27e-1)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "prognostic favourable (2.71e-4)" 11.5 10.6 8.8 25.5 9.7 7.9 9.3 10.1 12.2 11.2 10.2 8.7 20.2 23.8 12.1 13.2 7.8 12.1 11.4 8.1 8.2 9.6 10.1 22.5 10.4 17.4 12.6 8.3 14.7 31.0 7.4 13.9 13.7 10.6 13.7 4.6 7.7 17.0 25.2 12.2 9.7 19.4 9.2 8.4 18.6 18.5 9.2 9.2 16.7 12.5 7.9 12.1 9.9 11.8 12.5 12.5 13.8 13.9 11.2 15.9 13.8 3.3 2.3 0.9 6.0 0.8 1.7 0.6 4.6 1.1 1.4 1.7 1.7 1.4 7.7 7.9 1.3 7.4 1.1 2.7 0.1 3.0 12.9 10.8 0.5 2.3 1.3 4.5 1.7 1.3 1.6 1.2 0.5 1.2 10.5 3.3 0.4 1.3 6.3 2.4 0.0 7.3 9.0 6.9 14.2 1.1 1.1 3.2 12.9 5.5 3.4 7.3 3.3 3.5 3.9 3.4 7.1 6.2 2.7 12.0 14.4 12.0 1.8 11.5 5.2 12.6 13.8 8.8 12.7 13.9 15.9 12.5 12.6 14.4 12.5 10.5 11.8 12.1 13.8 11.2 12.1 9.8 10.4 13.8 8.8 9.7 10.1 12.2 8.2 9.6 12.6 8.3 10.6 9.2 TRIM28 "KAP1, PPP1R157, RNF96, TF1B, TIF1B" ENSG00000130726 "Tripartite motif containing 28" Q13263 19 58544091-58550722 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 217.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010066, HPA064033" Supported Enhanced Nucleoplasm "Intracellular and membrane" 140000 Nucleoplasm "CAB010066: AB_2209905, HPA064033: " "unprognostic (2.76e-1)" "unprognostic (1.40e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (2.99e-1)" "prognostic unfavourable (1.85e-6)" "unprognostic (1.20e-2)" "unprognostic (2.10e-2)" "unprognostic (2.66e-1)" "unprognostic (4.92e-3)" "unprognostic (9.28e-2)" "unprognostic (2.47e-2)" "unprognostic (4.67e-2)" "unprognostic (7.34e-2)" "unprognostic (4.22e-1)" "unprognostic (3.28e-2)" 24.2 26.4 17.9 40.1 20.6 52.2 30.6 34.5 26.3 46.7 36.5 26.2 26.2 26.8 43.3 30.0 34.1 34.5 38.5 28.4 18.5 16.4 27.3 42.3 29.5 38.1 29.2 22.7 69.3 47.0 30.7 25.7 45.6 22.8 37.6 18.5 21.5 31.8 32.4 56.5 41.2 27.5 38.4 17.9 34.9 32.9 48.1 23.1 119.9 50.6 33.5 33.5 34.0 46.4 13.7 14.6 5.0 7.6 16.0 16.9 6.3 35.8 77.2 41.5 30.6 18.1 13.9 46.3 23.6 21.4 23.0 17.6 53.8 30.2 39.5 15.6 20.3 24.6 46.9 33.9 15.1 20.2 217.0 67.9 35.0 42.7 19.3 43.0 43.7 18.8 18.9 29.4 23.1 21.5 33.0 22.3 21.2 53.1 60.1 53.1 29.1 49.8 57.1 25.1 42.4 20.6 59.6 41.6 32.6 24.6 32.0 13.1 22.0 41.9 19.8 54.2 21.5 11.8 42.2 28.7 46.8 44.1 24.5 32.2 34.3 1.3 7.1 5.0 8.9 7.6 11.6 11.5 12.8 12.3 9.0 13.7 16.9 15.1 3.8 16.0 4.9 14.6 8.2 6.3 17.9 20.6 34.5 26.3 18.5 16.4 29.2 22.7 22.8 23.1 TRIM31 "C6orf13, HCG1, HCGI, RNF" ENSG00000204616 "Tripartite motif containing 31" Q9BZY9 6 30102897-30113106 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.3;lymphoid tissue: 7.4;urinary bladder: 12.2" "Cell line enriched" "Detected in single" 490 "RT4: 79.5" "Group enriched" "Detected in many" 5 "cervical cancer: 6.7;colorectal cancer: 25.8;pancreatic cancer: 11.4;stomach cancer: 19.8;urothelial cancer: 12.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046400 Uncertain "HPA046400: " "unprognostic (1.37e-1)" "unprognostic (7.78e-3)" "unprognostic (1.83e-1)" "unprognostic (7.05e-3)" "unprognostic (1.75e-1)" "unprognostic (9.37e-2)" "unprognostic (6.13e-2)" "unprognostic (1.32e-1)" "unprognostic (2.05e-1)" "unprognostic (1.11e-2)" "unprognostic (1.97e-2)" "unprognostic (1.92e-1)" "unprognostic (1.43e-3)" "unprognostic (5.84e-3)" "unprognostic (6.20e-2)" "unprognostic (1.60e-1)" "unprognostic (2.50e-3)" 0.1 0.0 0.1 7.4 0.1 0.0 0.1 0.1 0.1 0.2 16.3 0.1 0.1 1.2 0.1 0.1 0.1 0.1 3.3 0.1 0.1 0.0 0.1 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 2.1 0.4 0.1 0.1 0.1 0.1 0.1 13.7 0.7 0.1 0.1 4.8 2.0 0.1 0.1 0.1 0.1 0.1 12.2 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 TRIM32 "BBS11, HT2A, LGMD2H, TATIP" ENSG00000119401 "Tripartite motif containing 32" Q13049 9 116687302-116701300 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Bardet-Biedl syndrome, Ciliopathy, Disease mutation, Limb-girdle muscular dystrophy, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050060 Approved Approved "Intermediate filaments" "Intermediate filaments" "HPA050060: " "unprognostic (2.47e-2)" "unprognostic (7.06e-3)" "unprognostic (5.50e-2)" "unprognostic (3.63e-1)" "unprognostic (5.08e-2)" "prognostic unfavourable (4.53e-4)" "prognostic unfavourable (4.72e-4)" "unprognostic (2.41e-3)" "unprognostic (2.92e-1)" "unprognostic (5.01e-2)" "unprognostic (1.79e-2)" "unprognostic (5.63e-2)" "unprognostic (6.03e-2)" "unprognostic (7.06e-2)" "unprognostic (2.73e-1)" "unprognostic (6.64e-3)" "unprognostic (9.77e-2)" 9.5 9.1 6.6 5.8 11.5 0.8 8.0 23.2 17.1 12.8 7.9 7.2 6.2 6.7 17.0 8.0 8.8 15.9 8.2 8.9 5.7 7.3 6.2 5.0 6.3 8.4 5.7 9.8 12.6 12.5 12.2 7.7 7.0 9.1 10.3 7.4 10.4 10.9 9.2 23.9 6.6 8.9 12.9 5.3 6.9 6.8 6.5 2.2 9.4 8.4 6.2 8.3 11.1 8.8 6.1 3.5 0.2 2.6 5.6 16.0 4.7 6.4 14.9 8.8 9.7 17.9 12.9 6.7 12.1 13.3 13.8 11.6 9.9 7.1 6.7 5.4 18.5 13.9 10.7 13.6 12.6 5.9 5.2 3.6 9.6 6.0 9.3 2.4 11.9 11.0 12.3 13.0 7.7 8.9 5.0 5.7 16.1 8.3 6.4 0.0 8.0 9.0 7.6 23.7 4.4 5.6 15.2 8.8 4.5 9.5 6.6 6.9 18.4 2.4 11.0 12.8 10.3 9.4 9.1 9.4 2.5 10.5 10.7 1.6 12.5 0.0 1.3 0.0 9.3 2.6 7.2 6.1 8.2 7.4 1.8 4.4 8.3 8.4 0.2 5.6 2.1 3.5 16.0 4.7 6.6 11.5 23.2 17.1 5.7 7.3 5.7 9.8 9.1 2.2 TRIM33 "FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA" ENSG00000197323 "Tripartite motif containing 33" Q9UPN9 1 114392777-114511160 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004345 Supported Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA004345: AB_1858287" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "prognostic favourable (6.20e-4)" "unprognostic (1.09e-2)" "unprognostic (8.42e-3)" "prognostic favourable (8.93e-4)" "unprognostic (1.34e-2)" "unprognostic (1.83e-1)" "unprognostic (6.75e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-2)" "unprognostic (4.84e-2)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" 15.2 12.8 16.9 18.4 19.9 27.1 17.1 38.3 21.8 16.9 14.3 11.0 21.9 10.9 19.8 38.3 16.4 15.0 15.6 10.8 18.1 12.5 17.3 15.0 14.3 15.2 12.1 18.0 19.8 15.7 21.8 22.4 27.2 15.2 16.5 13.0 10.7 16.4 19.1 14.3 19.5 14.8 20.2 12.9 14.9 14.1 29.0 16.3 20.5 17.9 9.8 16.6 17.9 28.7 3.4 4.0 12.2 2.8 4.7 4.4 1.0 12.9 7.0 13.2 9.9 5.6 5.9 22.5 6.6 7.0 9.2 9.8 7.9 5.5 13.8 6.8 7.7 7.5 12.0 7.7 12.7 10.4 7.1 13.3 9.2 9.1 6.2 16.8 11.1 5.6 5.7 10.9 11.2 7.7 16.6 9.8 8.8 48.5 16.9 7.1 17.8 7.1 14.6 20.2 4.5 6.6 20.4 9.2 9.7 12.5 15.1 11.9 6.9 9.2 8.6 6.4 10.5 14.8 9.2 6.9 6.4 14.5 9.1 9.8 18.2 12.2 1.6 7.4 3.5 1.8 3.1 3.4 3.7 3.7 2.0 2.2 2.9 4.4 4.8 4.7 2.8 4.0 2.0 1.0 16.9 19.9 38.3 21.8 18.1 12.5 12.1 18.0 15.2 16.3 TRIM36 "HAPRIN, RBCC728, RNF98" ENSG00000152503 "Tripartite motif containing 36" Q9NQ86 5 115124762-115180546 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 88.8" "Cell line enhanced" "Detected in many" "RH-30: 17.8;SCLC-21H: 19.9;SH-SY5Y: 14.5" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "myeloid DC: 7.5;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 43 "dendritic cells: 7.5;granulocytes: 4.2;monocytes: 7.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061321 Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA061321: " "unprognostic (6.36e-2)" "unprognostic (2.99e-1)" "unprognostic (4.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (2.31e-2)" "unprognostic (5.33e-6)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (1.84e-1)" "unprognostic (1.90e-1)" "unprognostic (2.82e-13)" "unprognostic (4.95e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-1)" "unprognostic (6.80e-3)" 1.0 1.4 6.8 1.4 7.6 0.8 3.2 0.6 11.7 1.4 4.8 7.7 0.0 8.2 1.1 1.0 0.8 1.9 1.0 0.7 10.1 7.2 0.9 0.9 1.6 0.8 7.1 8.6 3.5 1.5 0.7 8.2 1.3 18.3 5.7 4.8 5.1 1.0 1.0 0.7 1.0 7.9 1.1 8.7 0.9 2.0 88.8 4.7 0.0 0.8 0.0 0.9 0.8 1.0 0.1 7.5 4.2 7.7 0.0 0.0 0.8 2.4 0.7 1.2 6.2 0.1 0.1 1.5 0.5 2.1 1.1 1.3 0.9 1.2 0.0 1.0 0.1 0.6 5.8 1.1 0.8 0.4 1.9 4.3 2.5 1.2 0.2 4.2 3.6 0.1 1.1 0.5 1.5 0.0 0.1 5.9 1.7 3.3 1.1 3.8 4.9 2.8 0.9 17.8 1.4 0.6 0.0 19.9 14.5 3.8 0.4 2.3 4.2 5.3 0.5 1.7 1.3 1.3 1.9 0.9 0.5 0.0 1.9 2.4 0.8 0.0 1.7 4.2 0.0 1.6 0.0 0.0 0.0 0.0 7.5 0.1 0.0 0.0 0.3 0.0 7.7 1.6 0.0 0.8 6.8 7.6 0.6 11.7 10.1 7.2 7.1 8.6 18.3 4.7 TRIM37 "KIAA0898, MUL, POB1, TEF3" ENSG00000108395 "Tripartite motif containing 37" O94972 17 58982638-59106921 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Repressor, Transferase" "Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 46.1" "Cell line enriched" "Detected in all" 4 "MCF7: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "basophil: 20.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021911 Uncertain "HPA021911: AB_10964487" "unprognostic (4.07e-2)" "unprognostic (1.71e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" "unprognostic (2.11e-1)" "unprognostic (1.06e-1)" "prognostic unfavourable (4.99e-6)" "unprognostic (7.83e-2)" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-3)" "unprognostic (4.79e-2)" "unprognostic (2.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.46e-1)" "unprognostic (4.27e-2)" "unprognostic (3.04e-2)" 6.7 10.3 17.4 7.1 24.4 5.1 7.1 33.4 33.9 7.2 5.9 7.9 4.9 5.2 7.4 9.2 7.1 8.2 7.5 9.1 19.0 19.5 6.5 6.5 7.4 6.8 17.7 18.1 5.5 6.5 6.1 8.9 7.7 32.4 8.1 6.2 5.8 4.4 8.1 7.9 6.1 4.6 8.9 8.7 6.4 5.3 46.1 7.4 6.8 11.1 2.1 6.7 6.8 4.4 3.8 3.4 20.0 3.1 2.9 6.5 2.5 6.8 10.0 6.9 9.1 6.8 6.2 11.1 7.5 11.7 8.2 13.5 6.1 4.7 6.4 11.5 7.8 5.9 10.0 5.6 13.1 12.7 9.7 9.9 9.5 8.4 12.0 5.1 5.3 5.0 5.4 10.2 13.3 10.5 7.7 9.5 8.1 75.3 10.3 3.0 10.1 6.7 4.6 18.2 4.5 7.8 8.8 16.8 9.9 7.8 3.3 7.3 9.7 2.4 8.1 12.9 15.4 11.7 8.5 9.6 14.1 5.7 8.8 5.5 6.0 20.0 3.1 3.6 6.3 2.4 5.9 3.2 4.1 4.1 3.4 3.8 3.7 4.7 4.5 2.9 2.3 2.6 6.5 2.5 17.4 24.4 33.4 33.9 19.0 19.5 17.7 18.1 32.4 7.4 TRIM38 "RNF15, RORET" ENSG00000112343 "Tripartite motif containing 38" O00635 6 25962802-25991226 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031685 Approved Approved "Plasma membrane,Cell Junctions,Centrosome" Centrosome "Plasma membrane, Cell Junctions" "HPA031685: AB_10603218" "unprognostic (6.62e-2)" "unprognostic (1.65e-3)" "unprognostic (3.34e-1)" "unprognostic (2.72e-2)" "unprognostic (1.25e-1)" "unprognostic (6.51e-2)" "unprognostic (7.79e-2)" "unprognostic (3.27e-2)" "unprognostic (2.78e-2)" "prognostic favourable (8.95e-5)" "unprognostic (2.81e-2)" "unprognostic (6.28e-2)" "unprognostic (2.73e-1)" "unprognostic (3.36e-1)" "unprognostic (4.49e-2)" "prognostic favourable (8.20e-5)" "prognostic favourable (4.94e-9)" 13.3 8.4 2.5 15.7 2.3 12.0 7.9 1.1 3.4 17.2 12.1 3.1 20.5 6.7 26.2 22.3 15.7 8.9 9.2 5.8 2.8 2.3 26.1 8.8 14.0 14.4 3.7 1.8 11.5 4.3 1.0 4.3 10.3 3.5 15.5 7.8 9.2 9.8 16.5 9.0 5.3 14.6 13.1 4.5 17.6 6.6 5.3 2.9 16.6 13.7 9.5 20.1 18.0 15.4 16.5 10.1 12.1 12.9 6.7 7.9 6.3 3.5 2.0 0.3 4.3 10.3 13.9 3.6 4.5 8.9 8.7 14.5 1.5 3.8 7.9 7.4 5.5 5.6 2.7 4.4 5.2 7.9 1.8 3.5 3.3 1.4 13.7 4.2 7.4 13.8 3.2 5.4 1.9 7.5 2.3 4.4 10.3 1.7 4.0 4.8 1.4 2.7 6.2 4.3 8.2 10.4 7.0 0.1 0.1 3.4 7.1 12.0 1.0 5.5 7.7 1.6 2.7 2.7 3.0 5.1 3.7 8.9 4.2 5.2 9.6 10.1 10.6 4.7 7.6 12.9 7.4 14.3 6.5 6.8 10.1 16.5 6.2 6.7 12.1 6.7 11.4 9.5 7.9 6.3 2.5 2.3 1.1 3.4 2.8 2.3 3.7 1.8 3.5 2.9 TRIM39 RNF23 ENSG00000204599 "Tripartite motif containing 39" Q9HCM9 6 30326479-30343729 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA051120, HPA059496" Uncertain Supported Cytosol Cytosol "HPA051120: , HPA059496: " "unprognostic (2.90e-1)" "unprognostic (1.61e-2)" "unprognostic (2.79e-2)" "unprognostic (2.86e-2)" "unprognostic (6.38e-2)" "unprognostic (4.55e-2)" "unprognostic (1.46e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-1)" "unprognostic (9.44e-2)" "prognostic favourable (2.50e-4)" "unprognostic (1.30e-2)" "unprognostic (4.69e-2)" "unprognostic (6.35e-3)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (2.39e-3)" 8.6 7.6 5.2 14.3 6.4 11.8 7.4 8.6 7.6 10.2 11.2 7.3 9.7 7.1 10.0 15.2 11.9 8.5 13.6 6.1 5.4 5.5 7.6 9.6 11.1 6.7 7.7 6.3 10.3 9.1 8.9 11.4 11.6 7.1 7.9 7.1 11.4 8.2 15.5 9.9 6.5 10.9 8.8 6.0 13.1 8.0 14.1 7.2 7.8 8.9 8.3 10.1 9.1 12.3 3.4 1.6 8.4 2.5 4.4 5.2 2.1 4.4 0.2 3.8 6.8 1.8 1.8 3.9 2.0 2.5 3.0 2.7 5.3 0.6 5.6 4.1 3.8 1.4 4.4 3.1 3.1 4.4 4.8 4.5 0.7 1.9 3.9 6.6 5.0 2.1 2.6 3.8 4.2 1.9 6.6 4.5 3.9 4.0 1.4 1.4 5.1 3.2 3.1 0.8 4.2 3.3 4.3 8.3 4.1 1.6 3.3 3.9 4.4 1.7 1.7 3.3 2.7 4.0 6.8 8.2 10.0 5.8 2.0 2.4 5.1 1.4 1.7 6.8 5.2 2.5 4.6 3.4 3.7 3.8 1.6 3.3 4.4 4.1 8.4 4.4 2.4 1.2 2.9 2.1 5.2 6.4 8.6 7.6 5.4 5.5 7.7 6.3 7.1 7.2 TRIM4 RNF87 ENSG00000146833 "Tripartite motif containing 4" Q9C037 7 99876958-99919600 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019356, HPA029461" Approved Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA019356: AB_1856376, HPA029461: AB_10600834" "unprognostic (1.88e-1)" "unprognostic (2.97e-2)" "unprognostic (3.37e-1)" "unprognostic (3.46e-2)" "unprognostic (1.80e-2)" "unprognostic (7.06e-2)" "unprognostic (1.22e-1)" "unprognostic (5.42e-2)" "unprognostic (3.85e-2)" "unprognostic (2.67e-3)" "unprognostic (2.48e-2)" "unprognostic (1.60e-1)" "prognostic favourable (7.36e-6)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (7.46e-2)" "unprognostic (5.65e-2)" 19.1 22.6 13.5 22.1 15.9 6.7 22.1 20.1 15.5 19.5 17.3 12.4 22.5 13.9 21.9 18.8 16.4 19.0 19.8 11.1 13.3 9.3 16.6 17.9 21.1 22.4 15.3 8.8 35.0 23.2 18.9 27.4 16.1 12.2 21.9 15.7 18.4 19.4 33.8 9.4 20.7 18.3 18.1 11.9 18.2 17.4 16.2 14.5 18.4 20.5 11.9 18.8 20.0 28.9 18.6 17.0 20.0 19.2 13.9 30.3 17.4 9.5 11.5 6.9 5.7 18.1 17.0 3.1 16.1 19.7 13.5 15.7 6.1 9.5 14.0 0.1 13.7 11.4 9.1 9.9 13.8 14.2 0.7 11.4 6.1 9.6 25.6 16.4 16.3 18.1 21.2 10.5 26.6 11.8 16.6 21.6 11.2 11.9 12.1 14.8 5.2 9.9 6.9 9.8 15.9 14.9 12.4 8.1 5.7 12.3 18.9 19.2 8.7 9.5 14.3 15.0 13.4 28.6 15.5 18.2 19.9 11.3 9.8 18.5 19.8 20.0 19.2 15.3 20.6 19.2 23.8 18.6 21.6 23.5 17.0 18.6 30.3 22.2 8.2 13.9 16.6 12.7 21.5 17.4 13.5 15.9 20.1 15.5 13.3 9.3 15.3 8.8 12.2 14.5 TRIM41 "MGC1127, RINCK" ENSG00000146063 "Tripartite motif containing 41" Q8WV44 5 181222499-181235809 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 43.7" "Cell line enhanced" "Detected in all" "HDLM-2: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024204 Approved Supported "Nucleoli,Nuclear bodies" "Nucleoli, Nuclear bodies" "HPA024204: AB_1858299" "unprognostic (1.13e-1)" "unprognostic (7.05e-2)" "unprognostic (1.23e-2)" "unprognostic (7.93e-2)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (9.56e-2)" "unprognostic (7.24e-2)" "unprognostic (8.66e-2)" "unprognostic (6.87e-2)" "unprognostic (2.21e-3)" "unprognostic (2.07e-1)" "unprognostic (5.17e-3)" "unprognostic (2.45e-3)" "unprognostic (1.34e-1)" "prognostic unfavourable (4.22e-4)" "unprognostic (2.68e-2)" 10.0 8.3 25.5 9.4 24.3 9.3 5.4 7.3 17.0 6.9 6.5 19.8 8.8 11.2 6.1 8.3 7.3 8.4 7.0 9.8 26.9 20.4 10.7 7.6 6.9 6.0 37.3 12.5 5.9 12.3 18.8 7.6 7.3 17.0 7.0 4.0 7.8 8.3 8.4 30.0 9.0 9.0 5.3 43.7 7.5 9.5 19.1 18.3 10.6 11.3 7.2 7.2 5.8 5.2 2.2 2.4 3.9 2.3 1.9 4.3 1.4 4.6 12.1 4.5 7.5 5.4 5.4 10.6 6.8 3.7 5.0 4.7 10.2 7.0 7.8 11.1 4.6 8.8 4.7 16.3 2.7 38.5 14.9 8.9 11.9 5.8 5.2 6.5 6.1 4.7 8.4 6.2 2.2 2.8 11.1 9.7 2.8 16.6 9.8 7.3 4.2 5.8 9.3 6.9 10.2 2.9 7.4 7.0 6.6 6.3 7.4 9.5 14.8 7.4 5.9 6.9 4.7 4.1 5.1 21.4 13.5 11.1 7.2 7.7 5.8 0.9 1.4 2.2 2.4 1.1 3.6 1.9 2.5 4.3 1.6 2.2 2.6 3.1 3.9 1.9 2.3 2.4 3.2 1.4 25.5 24.3 7.3 17.0 26.9 20.4 37.3 12.5 17.0 18.3 TRIM5 "RNF88, TRIM5alpha" ENSG00000132256 "Tripartite motif containing 5" Q9C035 11 5663557-5938619 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Autophagy, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013497, HPA023420, HPA023422" Approved Supported Cytosol Cytosol "CAB013497: , HPA023420: AB_1856378, HPA023422: AB_1856379" "unprognostic (2.60e-1)" "unprognostic (9.62e-2)" "unprognostic (2.04e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (4.74e-3)" "unprognostic (5.48e-3)" "unprognostic (5.82e-2)" "unprognostic (1.49e-1)" "unprognostic (6.76e-3)" "unprognostic (8.54e-3)" "unprognostic (1.64e-1)" "unprognostic (2.20e-2)" "unprognostic (1.90e-1)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (6.12e-2)" 12.5 15.0 3.7 11.6 6.7 3.0 10.7 2.4 5.1 14.2 8.5 4.8 20.1 8.4 16.1 19.9 12.0 11.9 9.9 7.8 5.6 2.9 15.1 16.2 15.2 9.2 6.5 2.9 15.3 24.8 6.1 9.2 12.2 8.8 11.8 8.3 11.8 22.0 12.4 3.0 6.5 13.2 12.0 9.0 19.8 9.5 7.7 6.5 24.9 20.5 7.9 13.3 14.8 12.3 3.9 11.7 13.8 9.8 5.9 5.4 4.6 4.6 7.2 12.3 8.6 13.7 12.6 3.6 9.9 18.6 20.3 27.5 7.3 9.3 3.0 7.8 9.7 7.6 10.0 14.5 9.2 6.4 2.7 9.0 5.0 5.8 12.2 6.6 9.7 9.5 13.0 6.7 17.8 31.3 9.4 6.1 17.0 2.1 5.4 3.0 5.6 5.1 8.4 2.6 0.8 14.1 8.9 0.3 0.7 7.0 10.1 4.4 5.2 3.8 23.6 9.6 12.7 1.8 2.4 5.5 3.8 1.2 8.9 4.4 9.8 10.2 9.8 12.9 5.4 9.8 5.3 3.9 4.1 4.3 11.7 3.9 3.4 4.9 13.8 5.9 9.2 9.7 3.3 4.6 3.7 6.7 2.4 5.1 5.6 2.9 6.5 2.9 8.8 6.5 TRIM50 "FLJ32804, TRIM50A" ENSG00000146755 "Tripartite motif containing 50" Q86XT4 7 73312539-73328082 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "pancreas: 17.2;stomach 1: 22.8" "Cell line enriched" "Detected in single" 33 "Hep G2: 12.0" "Group enriched" "Detected in some" 8 "liver cancer: 2.9;renal cancer: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019862, HPA047843" Uncertain Approved Cytosol Cytosol "HPA019862: AB_1858305, HPA047843: " "unprognostic (1.93e-1)" "unprognostic (3.93e-1)" "unprognostic (1.07e-2)" "unprognostic (5.96e-2)" "unprognostic (3.87e-1)" "unprognostic (2.66e-2)" "unprognostic (1.49e-1)" "unprognostic (3.04e-3)" "unprognostic (2.63e-2)" "unprognostic (2.00e-1)" "unprognostic (2.13e-1)" "unprognostic (1.33e-1)" "prognostic favourable (9.36e-7)" "unprognostic (3.91e-2)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (2.25e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 17.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 1.0 0.0 0.0 0.1 22.8 4.4 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 12.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIM56 RNF109 ENSG00000169871 "Tripartite motif containing 56" Q9BRZ2 7 101085439-101097967 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024358 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA024358: AB_1858308" "unprognostic (6.47e-2)" "unprognostic (1.34e-1)" "unprognostic (1.99e-2)" "unprognostic (1.62e-1)" "unprognostic (9.44e-3)" "unprognostic (8.30e-2)" "prognostic unfavourable (3.87e-4)" "unprognostic (2.63e-1)" "unprognostic (4.11e-1)" "unprognostic (3.90e-1)" "unprognostic (1.91e-1)" "unprognostic (1.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.47e-3)" "unprognostic (8.13e-2)" "unprognostic (1.49e-1)" "prognostic favourable (2.13e-4)" 14.3 12.0 6.2 15.7 9.3 4.7 24.5 3.2 11.1 14.9 15.0 6.8 22.3 9.7 14.3 13.1 12.9 12.8 13.7 8.7 7.5 5.2 10.8 10.4 23.7 11.7 15.8 5.2 17.3 10.8 10.7 15.2 14.0 8.8 12.5 8.3 7.5 12.2 22.1 8.7 13.2 12.8 15.2 8.5 17.2 10.3 5.6 12.0 9.7 14.0 9.1 12.0 13.6 22.0 3.3 2.1 7.4 2.4 7.7 3.6 1.0 9.9 12.5 5.4 6.9 12.5 13.0 6.5 8.3 7.4 13.5 12.6 5.9 14.5 11.8 9.0 6.9 11.5 2.2 7.6 9.1 11.8 3.5 7.4 15.7 4.4 11.2 13.1 16.9 8.2 11.1 8.8 14.4 7.1 12.9 15.0 9.3 13.6 11.0 14.6 5.4 10.4 10.2 8.8 7.7 7.1 10.4 0.3 0.2 9.2 25.8 7.0 5.9 8.6 13.4 19.0 16.9 14.2 8.9 7.4 7.4 9.3 9.4 10.7 14.8 2.5 2.4 2.1 3.6 1.5 2.6 2.0 2.7 2.3 0.8 3.3 2.6 3.4 7.4 7.7 2.1 2.1 1.1 1.0 6.2 9.3 3.2 11.1 7.5 5.2 15.8 5.2 8.8 12.0 TRIM58 BIA2 ENSG00000162722 "Tripartite motif containing 58" Q8NG06 1 247857199-247878205 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;placenta: 22.4;thyroid gland: 15.2" "Cell line enhanced" "Detected in some" "HAP1: 7.9;HEL: 21.0;K-562: 11.6;PC-3: 20.2;U-2 OS: 16.5;WM-115: 21.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023637 Uncertain 310000 "HPA023637: AB_1858309" "unprognostic (3.85e-1)" "unprognostic (5.24e-3)" "unprognostic (7.00e-2)" "unprognostic (6.52e-4)" "unprognostic (1.46e-1)" "unprognostic (3.47e-2)" "unprognostic (1.10e-1)" "unprognostic (4.14e-5)" "unprognostic (3.59e-1)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (5.00e-2)" "unprognostic (3.31e-1)" "unprognostic (1.08e-2)" "unprognostic (3.34e-1)" "unprognostic (1.00e-2)" "unprognostic (2.57e-2)" 0.7 0.8 1.3 1.0 4.4 24.8 0.7 0.3 3.7 0.6 1.3 0.2 0.0 0.3 0.5 0.4 0.5 1.4 0.5 0.8 1.5 3.2 0.5 0.6 3.4 0.4 2.4 1.2 1.1 0.4 0.3 0.7 22.4 6.9 1.7 1.0 1.1 0.5 0.4 0.5 1.2 0.6 0.8 1.3 5.8 0.7 4.9 0.1 0.0 15.2 0.0 0.4 1.9 0.7 3.1 0.6 3.7 0.7 1.7 0.3 1.9 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 7.9 0.0 0.0 0.0 0.8 21.0 0.0 0.0 0.0 2.8 1.6 0.0 0.0 0.0 0.0 0.0 11.6 0.1 0.0 0.0 0.0 0.1 1.3 20.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.1 0.0 0.0 16.5 0.0 0.0 3.5 0.0 0.0 0.0 5.9 21.3 2.8 0.7 1.8 0.3 0.5 0.2 3.1 0.2 0.2 0.6 1.0 0.3 0.2 3.7 1.7 0.6 0.6 0.2 1.9 1.3 4.4 0.3 3.7 1.5 3.2 2.4 1.2 6.9 0.1 TRIM6 RNF89 ENSG00000121236 "Tripartite motif containing 6" Q9C030 11 5596109-5612958 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 42.7" "Cell line enhanced" "Detected in many" "BEWO: 13.6;NTERA-2: 16.2;TIME: 13.6;U-2 OS: 15.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "neutrophil: 3.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA060514 Uncertain "HPA060514: " "unprognostic (9.00e-2)" "unprognostic (2.10e-3)" "unprognostic (9.16e-3)" "unprognostic (1.82e-1)" "unprognostic (3.25e-3)" "unprognostic (3.25e-3)" "unprognostic (2.35e-2)" "unprognostic (3.26e-3)" "unprognostic (8.59e-2)" "unprognostic (3.40e-2)" "unprognostic (8.61e-2)" "unprognostic (3.90e-1)" "unprognostic (5.68e-2)" "unprognostic (4.65e-4)" "unprognostic (4.77e-1)" "unprognostic (3.33e-2)" "unprognostic (4.36e-1)" 3.7 5.8 0.6 1.5 1.3 1.3 3.0 0.2 1.4 4.2 2.6 1.4 3.2 0.1 4.2 4.3 6.0 3.1 1.8 2.6 0.8 0.7 42.7 1.1 2.2 0.2 0.7 0.6 3.9 1.8 1.9 1.9 10.9 2.1 3.9 1.2 6.6 14.7 3.9 1.3 1.1 2.2 4.7 1.4 2.8 1.6 15.5 1.0 1.6 3.8 1.1 3.2 4.9 3.7 0.3 2.2 3.9 0.7 1.0 0.3 0.4 0.5 11.7 0.8 0.0 1.4 2.2 13.6 3.1 2.3 3.1 3.1 0.3 2.5 0.0 1.8 3.1 2.1 5.3 4.8 4.5 0.3 3.6 1.4 1.2 0.0 0.5 4.6 6.4 3.8 4.6 4.4 3.1 2.7 5.5 0.2 1.3 0.2 0.0 0.6 16.2 4.1 5.4 0.0 0.1 0.7 4.7 0.0 0.1 0.0 6.1 0.6 2.3 0.8 13.6 3.0 15.9 0.0 3.3 0.1 0.1 0.0 2.7 0.0 2.5 0.7 0.7 1.4 0.3 0.0 0.1 0.3 0.1 0.0 2.2 0.2 0.1 0.1 3.9 1.0 0.0 0.9 0.1 0.4 0.6 1.3 0.2 1.4 0.8 0.7 0.7 0.6 2.1 1.0 TRIM62 "DEAR1, FLJ10759" ENSG00000116525 "Tripartite motif containing 62" Q9BVG3 1 33145402-33182059 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050061 Approved "Vesicles,Focal adhesion sites" "Vesicles, Focal adhesion sites" "HPA050061: " "unprognostic (1.57e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (2.62e-2)" "unprognostic (1.14e-2)" "unprognostic (5.80e-2)" "unprognostic (5.10e-5)" "unprognostic (2.05e-2)" "unprognostic (1.14e-1)" "unprognostic (4.32e-2)" "unprognostic (3.55e-3)" "unprognostic (3.66e-1)" "prognostic unfavourable (7.08e-5)" "unprognostic (2.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (2.05e-3)" 4.8 11.8 10.1 6.4 19.2 9.3 6.2 19.0 13.9 5.6 4.9 31.8 1.6 5.6 4.9 6.9 6.9 5.1 4.9 5.3 12.3 10.5 5.3 2.7 5.6 9.6 28.1 9.1 6.7 4.8 7.5 9.2 19.6 15.4 8.7 5.4 5.0 10.8 7.5 6.7 20.5 5.8 6.9 12.8 8.3 6.5 4.0 23.7 8.7 6.3 5.1 10.4 9.8 7.3 3.0 1.8 6.0 3.5 1.7 8.5 2.1 2.9 2.3 20.7 3.4 5.2 2.3 6.3 2.9 8.7 5.4 4.8 2.4 3.0 4.7 3.2 2.6 6.0 4.1 3.8 5.2 4.5 3.2 5.4 2.5 1.9 5.0 1.7 13.5 4.5 3.5 7.2 1.8 5.4 0.8 3.1 5.5 7.8 5.3 1.7 4.9 2.9 6.7 10.9 2.2 3.5 7.7 5.0 3.1 3.2 12.3 13.8 3.4 1.2 5.2 2.3 3.2 6.6 2.2 5.8 2.5 2.3 4.3 3.2 2.8 2.2 2.0 6.0 2.7 3.5 4.6 2.2 4.1 3.7 1.8 3.0 2.8 2.7 4.4 1.7 2.2 0.8 8.5 2.1 10.1 19.2 19.0 13.9 12.3 10.5 28.1 9.1 15.4 23.7 TRIM68 "FLJ10369, RNF137, SS-56" ENSG00000167333 "Tripartite motif containing 68" Q6AZZ1 11 4598672-4608259 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023455 Uncertain Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA023455: AB_1858319" "unprognostic (4.77e-2)" "unprognostic (5.15e-2)" "unprognostic (1.18e-1)" "unprognostic (4.10e-2)" "unprognostic (4.13e-2)" "unprognostic (8.63e-2)" "unprognostic (2.01e-2)" "unprognostic (1.28e-1)" "unprognostic (2.01e-1)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "unprognostic (7.78e-2)" "prognostic favourable (4.14e-6)" "unprognostic (4.23e-2)" "unprognostic (2.98e-1)" "unprognostic (1.61e-1)" "unprognostic (1.37e-1)" 7.7 11.3 11.1 8.0 11.1 3.1 10.6 15.2 12.8 16.3 10.9 12.6 18.2 10.3 10.6 12.2 8.0 12.6 10.3 9.4 9.6 7.9 14.9 12.7 11.7 7.6 13.1 10.5 17.3 9.9 12.6 10.5 9.8 10.0 16.8 10.1 9.9 12.0 17.5 8.7 7.6 9.8 9.8 11.9 10.7 12.4 13.2 9.5 10.0 17.8 6.7 8.9 11.7 8.4 9.1 5.9 8.9 5.2 5.5 12.8 7.6 8.3 9.3 3.9 6.3 6.3 10.3 0.0 9.2 6.7 8.3 7.6 1.2 8.6 5.7 5.6 4.6 9.8 3.8 6.4 7.2 14.1 7.4 6.9 2.4 0.0 7.3 11.1 9.8 7.9 9.4 4.9 7.4 10.5 6.4 3.0 7.4 2.0 9.1 3.0 4.5 7.7 7.3 5.5 0.2 5.4 3.7 2.0 3.7 0.0 9.3 5.8 4.0 5.6 8.4 11.2 7.7 11.2 4.0 11.7 12.6 8.3 7.7 4.9 10.5 6.4 2.7 8.9 9.0 5.1 10.1 9.1 9.9 10.0 5.9 7.9 12.8 10.1 0.3 5.5 5.2 4.0 8.7 7.6 11.1 11.1 15.2 12.8 9.6 7.9 13.1 10.5 10.0 9.5 TRIM69 "RNF36, Trif, TRIMLESS" ENSG00000185880 "Tripartite motif containing 69" Q86WT6 15 44728988-44767829 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 68.6" "Cell line enhanced" "Detected in some" "Karpas-707: 4.0;U-266/70: 13.5;U-266/84: 3.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "T-reg: 8.2" "Lineage enriched" "Detected in many" 7 "T-cells: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA028894 Enhanced "HPA028894: AB_10603136" "unprognostic (4.82e-3)" "unprognostic (1.23e-2)" "unprognostic (4.10e-1)" "unprognostic (2.01e-1)" "unprognostic (1.75e-2)" "unprognostic (4.20e-1)" "unprognostic (9.27e-2)" "unprognostic (4.95e-2)" "unprognostic (6.49e-2)" "unprognostic (3.53e-3)" "unprognostic (1.38e-1)" "unprognostic (3.72e-2)" "prognostic favourable (2.26e-5)" "unprognostic (4.79e-2)" "unprognostic (1.82e-1)" "unprognostic (1.91e-2)" "unprognostic (1.49e-2)" 4.6 3.9 9.0 4.0 10.8 3.0 3.9 7.2 9.1 3.5 4.4 5.1 1.7 3.6 3.4 3.7 4.7 3.4 4.1 11.0 7.9 7.9 4.7 3.8 3.8 4.9 7.5 5.4 3.8 2.8 3.4 4.9 3.1 5.3 5.9 4.2 3.7 3.7 3.2 14.0 4.1 4.0 5.3 5.7 6.7 3.9 68.6 4.7 3.9 5.3 5.2 5.5 4.1 8.1 1.2 0.0 0.1 0.3 0.0 8.2 0.3 0.2 0.0 0.4 0.7 0.5 1.2 0.0 0.1 0.5 0.8 2.4 0.0 0.3 0.2 0.2 0.0 0.0 0.3 0.0 0.6 2.6 0.0 0.3 0.1 0.0 0.9 0.0 0.2 1.4 0.9 0.2 0.2 0.2 0.0 4.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.3 13.5 3.3 2.0 0.4 0.4 0.1 0.0 0.0 0.0 0.6 0.2 1.2 1.2 1.9 1.8 0.0 0.0 0.3 1.2 0.1 0.0 0.3 0.0 8.2 0.3 9.0 10.8 7.2 9.1 7.9 7.9 7.5 5.4 5.3 4.7 TRIM7 "GNIP, RNF90" ENSG00000146054 "Tripartite motif containing 7" Q9C029 5 181193924-181205293 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 81.8;tongue: 34.0" "Cell line enhanced" "Detected in many" "HaCaT: 11.2;HDLM-2: 23.8;PC-3: 13.2;TIME: 10.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 16 "cerebellum: 21.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "monocytes: 4.9;T-cells: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039213 Approved Approved Nucleoplasm,Vesicles,Cytosol Vesicles "Nucleoplasm, Cytosol" "HPA039213: AB_10795173" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (5.20e-2)" "unprognostic (1.10e-2)" "unprognostic (6.85e-2)" "unprognostic (1.80e-2)" "unprognostic (3.89e-4)" "unprognostic (3.45e-2)" "unprognostic (3.72e-1)" "unprognostic (1.64e-1)" "unprognostic (3.48e-2)" "unprognostic (1.97e-1)" "unprognostic (7.16e-3)" "unprognostic (1.26e-1)" "unprognostic (3.90e-2)" "unprognostic (6.17e-2)" "unprognostic (1.15e-2)" 1.3 0.9 0.1 0.9 0.5 0.5 3.4 21.7 1.3 2.5 0.8 0.3 1.1 0.5 1.0 6.4 13.0 0.6 1.7 2.2 0.1 0.8 2.2 0.5 0.9 0.6 0.2 0.2 0.6 4.2 1.6 1.9 0.5 0.5 2.0 0.6 0.6 5.9 1.1 81.8 9.5 0.6 0.9 0.3 0.8 1.4 0.9 0.2 0.1 3.3 34.0 13.5 1.6 2.9 0.7 0.8 0.1 4.9 0.5 2.2 1.1 6.1 2.9 0.0 0.3 0.5 0.5 0.1 1.4 0.0 0.5 1.2 0.2 8.0 0.4 4.3 1.7 11.2 3.2 9.2 0.1 23.8 1.3 0.5 7.8 0.1 1.6 0.0 1.3 0.1 7.1 0.2 4.6 2.6 0.3 1.3 0.2 0.8 0.3 0.2 0.0 13.2 0.3 4.2 0.9 3.3 0.0 0.3 0.7 2.9 0.1 4.0 0.7 0.2 10.8 0.1 2.4 0.4 4.2 1.9 0.2 0.7 0.3 0.4 1.0 0.0 4.9 0.1 1.4 1.9 2.2 0.4 1.2 1.4 0.8 0.7 2.2 1.8 0.1 0.5 1.4 0.6 2.2 1.1 0.1 0.5 21.7 1.3 0.1 0.8 0.2 0.2 0.5 0.2 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32818018-32897826 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 6.5;testis: 11.1" "Cell line enhanced" "Detected in some" "AF22: 12.4;BEWO: 37.5;CACO-2: 8.8;Hep G2: 24.2;NTERA-2: 33.2" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: , HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.1 0.0 0.7 0.1 1.9 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 2.7 0.7 2.2 0.0 6.5 0.0 0.2 0.0 0.1 0.0 0.0 0.5 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.1 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.5 0.3 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 37.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.6 0.0 24.2 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.2 2.6 33.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 1.9 0.0 0.5 2.7 0.7 0.2 0.0 1.9 0.0 TRIM8 "GERP, RNF27" ENSG00000171206 "Tripartite motif containing 8" Q9BZR9 10 102642310-102660680 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023560, HPA023561" Approved Supported Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "HPA023560: AB_10600414, HPA023561: AB_10601861" "unprognostic (4.32e-2)" "unprognostic (6.90e-2)" "unprognostic (3.02e-3)" "unprognostic (1.45e-1)" "unprognostic (1.78e-1)" "unprognostic (5.03e-1)" "unprognostic (3.82e-2)" "unprognostic (1.03e-1)" "unprognostic (2.15e-3)" "unprognostic (4.62e-2)" "unprognostic (5.41e-2)" "unprognostic (1.52e-1)" "unprognostic (9.55e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (8.34e-2)" "unprognostic (1.36e-2)" 31.7 18.4 26.1 23.9 25.2 17.0 18.0 26.1 31.6 31.8 19.5 22.9 15.4 15.8 18.0 14.3 17.8 21.6 19.8 25.0 23.2 18.0 27.2 21.9 23.0 25.4 20.1 20.0 19.3 35.9 24.7 14.7 17.5 16.3 17.4 8.1 19.4 28.5 18.5 34.8 14.6 23.7 13.6 15.7 22.5 21.2 11.7 21.9 48.3 26.6 14.5 30.3 21.4 15.9 9.0 11.9 17.8 5.3 5.5 7.2 3.9 27.6 6.5 6.4 10.5 7.1 14.4 6.0 9.9 20.2 10.8 8.7 11.7 33.4 8.9 26.7 22.0 10.2 4.3 13.3 8.9 9.0 8.4 22.5 5.4 26.7 18.1 5.0 9.0 16.5 7.4 23.7 14.0 14.3 4.2 13.4 8.4 18.0 9.5 16.9 3.5 13.2 4.8 14.4 4.4 12.8 19.5 3.9 7.6 5.5 6.8 13.1 19.2 10.0 26.6 14.5 6.5 8.1 22.2 12.3 8.0 5.2 22.1 12.6 3.6 10.7 4.8 2.6 6.8 4.4 6.7 9.0 7.2 5.3 4.1 7.0 6.4 5.5 17.8 5.5 5.3 11.9 6.9 3.9 26.1 25.2 26.1 31.6 23.2 18.0 20.1 20.0 16.3 21.9 TRIML2 "FLJ25801, SPRYD6" ENSG00000179046 "Tripartite motif family like 2" Q8N7C3 4 188091273-188109603 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "placenta: 9.8;testis: 6.2" "Cell line enhanced" "Detected in some" "A549: 21.1;BEWO: 11.7;hTCEpi: 13.7;NTERA-2: 21.7" "Cancer enriched" "Detected in some" 33 "testis cancer: 24.4" "Region enhanced" "Detected in single" "basal ganglia: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043838 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA043838: AB_10963835" "unprognostic (3.32e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (9.82e-2)" "unprognostic (1.21e-5)" "unprognostic (3.06e-2)" "unprognostic (1.65e-3)" "unprognostic (2.65e-1)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (1.20e-1)" "unprognostic (1.28e-3)" 0.1 0.1 0.2 0.1 1.4 0.0 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 9.8 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 6.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 21.1 0.0 0.0 0.0 0.1 11.7 0.1 0.9 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 4.0 0.1 0.0 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 4.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.1 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143702-14532128 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: " "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavourable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavourable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 29.7 13.7 27.6 15.8 18.9 5.8 30.3 32.6 29.7 13.7 18.5 11.3 9.2 8.3 23.1 19.3 10.4 12.2 25.2 15.1 18.9 15.0 11.7 12.6 15.8 10.9 11.0 17.7 28.9 11.5 17.2 19.6 13.7 12.3 16.3 16.5 23.3 10.5 14.0 19.8 16.0 15.6 22.7 11.6 24.2 13.7 11.3 11.5 7.4 10.0 11.9 12.3 15.6 16.9 3.8 2.7 0.3 1.9 4.3 0.6 0.4 12.2 4.4 10.6 5.0 22.7 29.8 12.1 11.3 13.5 9.1 10.5 2.8 4.8 2.8 8.5 15.4 3.7 1.7 5.3 18.9 7.8 2.5 1.5 11.8 3.5 11.8 3.7 4.2 13.9 5.6 32.2 10.3 8.0 0.3 1.9 22.0 2.3 0.0 2.6 2.6 4.0 2.8 6.4 9.4 8.9 5.5 4.8 19.5 9.6 2.5 5.0 1.5 0.5 18.6 17.6 11.2 12.7 13.3 0.0 0.6 3.6 62.5 2.4 4.1 0.3 1.5 0.0 0.1 1.9 0.3 2.0 0.0 0.0 1.4 3.8 0.0 0.0 0.0 4.3 1.4 2.7 0.6 0.4 27.6 18.9 32.6 29.7 18.9 15.0 11.0 17.7 12.3 11.5 TRIP12 KIAA0045 ENSG00000153827 "Thyroid hormone receptor interactor 12" Q14669 2 229763838-229923239 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Autism spectrum disorder, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036835, HPA045893" Enhanced Approved "Nuclear speckles" "Nuclear speckles" "HPA036835: , HPA045893: " "unprognostic (1.22e-1)" "unprognostic (4.87e-2)" "unprognostic (2.61e-1)" "unprognostic (3.33e-2)" "unprognostic (6.81e-2)" "unprognostic (1.88e-1)" "prognostic unfavourable (3.60e-4)" "unprognostic (3.37e-3)" "unprognostic (3.49e-3)" "unprognostic (4.87e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (6.83e-2)" "unprognostic (8.80e-2)" "unprognostic (2.01e-2)" 29.6 28.1 23.6 25.4 26.9 26.9 23.1 20.5 26.2 24.0 23.1 26.2 24.3 14.3 25.3 26.3 30.6 19.9 20.7 35.9 19.0 19.3 26.2 24.9 26.2 26.5 23.1 20.5 24.3 18.8 32.4 33.1 27.2 24.8 25.8 21.3 22.3 25.5 22.0 62.7 23.6 22.0 26.2 23.3 32.5 23.4 77.1 24.0 42.2 28.0 21.5 31.5 26.5 27.4 7.0 9.1 25.8 12.0 9.1 12.7 6.1 23.8 26.9 24.7 20.7 23.6 28.7 23.0 36.8 25.0 26.7 29.8 21.5 19.2 9.3 27.0 32.8 18.7 36.0 26.2 39.2 38.2 13.1 64.8 22.6 19.0 20.4 48.7 42.4 24.8 20.2 44.4 28.5 34.8 47.8 10.0 30.5 18.1 27.2 16.8 19.3 12.3 24.8 48.8 8.2 19.8 41.0 25.1 17.9 0.5 12.4 25.3 12.5 29.8 48.3 34.6 24.6 22.5 28.4 17.4 19.9 30.5 26.4 19.2 29.0 18.8 9.9 15.7 9.5 11.3 9.7 7.0 8.8 9.2 9.1 6.8 7.3 7.0 25.8 9.1 12.0 9.0 12.7 6.1 23.6 26.9 20.5 26.2 19.0 19.3 23.1 20.5 24.8 24.0 TRIT1 "FLJ20061, IPT" ENSG00000043514 "TRNA isopentenyltransferase 1" Q9H3H1 1 39841022-39883511 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024174 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA024174: AB_1858346" "unprognostic (4.61e-2)" "unprognostic (1.77e-1)" "unprognostic (8.38e-3)" "prognostic unfavourable (8.80e-4)" "unprognostic (4.00e-2)" "unprognostic (8.55e-2)" "prognostic unfavourable (5.34e-6)" "unprognostic (2.90e-1)" "unprognostic (2.21e-3)" "unprognostic (3.18e-2)" "unprognostic (3.54e-1)" "unprognostic (6.68e-3)" "prognostic unfavourable (7.08e-8)" "unprognostic (6.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (6.90e-2)" 9.5 10.3 12.9 10.4 19.1 8.0 19.8 25.8 18.4 15.1 13.4 15.9 22.7 11.4 19.3 21.3 19.8 18.4 9.1 15.9 12.5 12.0 14.6 13.2 11.9 14.8 13.9 10.4 16.7 27.7 14.1 26.7 17.6 14.4 21.4 15.8 13.5 15.1 23.9 10.1 22.9 11.7 18.0 9.8 14.0 12.9 17.3 17.9 15.4 19.2 9.4 14.7 17.2 17.5 3.9 13.4 0.9 6.6 2.4 5.2 2.8 14.5 6.7 14.6 14.9 7.3 11.0 22.0 9.7 13.0 15.6 17.6 12.9 19.2 8.4 12.8 8.2 14.8 21.0 16.7 21.9 10.3 10.6 18.0 15.6 8.0 16.9 17.5 9.9 9.3 15.1 19.5 19.3 12.5 24.4 10.2 9.7 7.1 13.3 18.8 19.6 6.1 14.2 18.3 19.3 14.8 18.7 16.6 11.1 13.9 9.5 10.6 10.5 30.0 8.9 10.4 12.8 18.0 16.0 13.8 10.8 17.1 13.2 17.9 9.0 0.0 6.6 0.9 2.7 4.9 5.2 3.9 2.6 2.9 13.4 3.2 3.4 3.5 0.1 2.4 5.8 11.6 2.7 2.8 12.9 19.1 25.8 18.4 12.5 12.0 13.9 10.4 14.4 17.9 TRMT1 "FLJ20244, TRM1" ENSG00000104907 "TRNA methyltransferase 1" Q9NXH9 19 13104902-13117567 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041130, HPA041380" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA041130: AB_10803995, HPA041380: AB_10793873" "unprognostic (2.10e-2)" "unprognostic (2.40e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-2)" "unprognostic (5.54e-2)" "unprognostic (1.08e-3)" "unprognostic (2.19e-2)" "unprognostic (1.59e-1)" "unprognostic (7.62e-2)" "unprognostic (1.91e-2)" "unprognostic (8.74e-3)" "prognostic unfavourable (9.87e-7)" "unprognostic (1.19e-3)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-2)" 15.5 15.0 19.1 19.8 23.5 23.1 16.6 19.5 22.6 15.0 16.3 17.3 15.5 14.9 19.2 19.0 17.6 19.6 19.4 13.2 15.7 13.4 14.4 17.3 13.5 26.8 22.1 14.7 29.1 23.8 16.3 14.4 14.4 21.9 18.1 14.5 10.9 14.9 15.6 21.4 22.1 16.1 16.5 12.4 25.0 16.3 16.8 20.1 12.2 15.6 12.1 19.6 17.3 18.8 11.2 14.9 3.1 15.7 4.3 10.2 8.5 15.3 10.4 11.3 19.1 11.5 14.7 16.2 17.3 8.7 19.1 16.6 11.1 12.7 19.3 22.7 9.3 14.3 18.8 15.2 8.9 12.6 26.3 15.3 26.7 18.6 20.8 30.7 18.1 20.8 20.5 19.9 18.7 14.0 33.2 6.2 11.8 17.0 12.4 33.2 26.7 24.4 21.0 14.5 26.6 11.9 15.7 26.8 12.2 10.8 22.5 18.0 8.7 17.2 15.6 27.6 10.7 16.6 30.3 10.7 20.7 17.8 12.9 32.5 14.3 1.2 15.7 0.5 8.1 11.9 7.7 10.4 8.6 7.7 14.9 11.2 10.2 7.7 3.1 4.3 7.5 8.8 5.6 8.5 19.1 23.5 19.5 22.6 15.7 13.4 22.1 14.7 21.9 20.1 TRMT10A "MGC27034, RG9MTD2, TRM10" ENSG00000145331 "TRNA methyltransferase 10A" Q8TBZ6 4 99546709-99564032 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Diabetes mellitus, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047601, HPA058241" Uncertain Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" "Nucleoli, Actin filaments" "Nucleoplasm, Cytosol" "HPA047601: , HPA058241: " "unprognostic (5.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-1)" "unprognostic (1.96e-3)" "unprognostic (2.10e-1)" "unprognostic (5.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.59e-2)" "unprognostic (3.65e-2)" "unprognostic (1.57e-1)" "unprognostic (3.51e-1)" "unprognostic (7.49e-3)" "unprognostic (3.32e-2)" "unprognostic (2.78e-2)" "prognostic unfavourable (2.14e-4)" "unprognostic (1.68e-2)" 7.0 8.9 6.5 7.5 8.9 3.3 13.1 6.1 8.7 4.6 6.0 9.3 7.5 7.3 5.5 7.2 9.2 10.1 6.1 5.0 7.9 6.7 9.1 16.8 4.9 7.4 9.2 6.1 6.6 12.4 6.7 12.2 10.0 9.7 7.4 6.9 2.5 7.3 4.7 9.3 6.5 10.4 5.1 10.5 7.0 7.6 16.7 10.1 10.7 10.8 5.1 8.0 7.2 10.8 8.8 10.0 9.2 7.6 5.8 7.1 4.0 6.6 4.7 9.2 4.7 5.5 7.7 6.7 8.1 3.1 5.7 4.3 3.9 8.3 9.2 3.1 4.8 3.9 10.7 5.1 8.8 11.7 4.7 6.3 4.1 6.4 5.2 16.0 6.8 4.9 13.2 5.7 12.5 5.8 14.6 8.3 4.8 7.7 13.5 3.3 5.5 4.6 7.8 8.8 5.9 7.7 5.5 5.8 5.0 4.4 24.6 8.1 8.0 6.9 4.2 5.8 6.0 4.7 9.2 5.8 9.7 8.4 4.4 9.4 4.1 4.0 7.6 3.7 3.8 7.1 3.1 6.3 6.5 6.4 10.0 8.8 6.7 6.2 9.2 5.8 6.2 5.6 7.1 4.0 6.5 8.9 6.1 8.7 7.9 6.7 9.2 6.1 9.7 10.1 TRMT10B "bA3J10.9, FLJ31455, RG9MTD3" ENSG00000165275 "TRNA methyltransferase 10B" Q6PF06 9 37753803-37778972 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021800 Uncertain Approved "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA021800: AB_1856214" "unprognostic (1.00e-2)" "unprognostic (1.78e-1)" "unprognostic (3.35e-2)" "unprognostic (3.89e-2)" "unprognostic (2.42e-2)" "unprognostic (7.68e-2)" "unprognostic (7.78e-2)" "prognostic favourable (3.91e-4)" "unprognostic (5.49e-3)" "unprognostic (1.71e-2)" "prognostic favourable (5.34e-4)" "unprognostic (1.40e-1)" "unprognostic (6.62e-2)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (9.58e-2)" "unprognostic (2.33e-3)" 7.4 10.3 9.9 10.9 10.3 10.1 9.8 13.7 12.3 10.6 11.8 12.7 12.8 8.3 17.3 9.5 10.4 9.6 10.6 7.0 9.9 9.2 8.2 8.0 8.6 13.1 16.4 9.8 15.4 10.5 9.0 13.8 7.4 10.0 14.8 7.1 12.1 10.3 12.1 7.8 20.4 9.7 11.8 12.7 12.1 10.8 5.0 10.4 10.0 12.4 5.6 13.6 14.8 10.1 9.2 4.6 6.6 5.3 4.6 7.6 2.7 5.4 6.4 8.3 7.3 5.1 4.1 3.9 5.4 3.8 5.4 4.7 3.9 4.8 10.0 4.0 4.0 6.3 3.9 6.4 5.0 4.3 6.9 8.8 15.7 4.0 9.3 8.9 6.3 4.7 6.7 4.7 9.2 5.5 7.0 4.4 4.1 3.8 9.2 7.1 7.4 7.9 9.3 2.9 5.2 5.2 5.0 11.3 10.8 4.3 5.4 4.7 5.9 6.6 5.5 4.3 6.1 6.8 4.6 5.0 6.9 8.0 2.5 7.2 8.6 6.6 5.3 2.8 6.7 4.6 7.6 6.6 6.0 6.3 2.5 9.2 7.3 6.7 5.4 4.6 3.2 4.6 3.9 2.7 9.9 10.3 13.7 12.3 9.9 9.2 16.4 9.8 10.0 10.4 TRMT10C "FLJ20432, MRPP1, RG9MTD1" ENSG00000174173 "TRNA methyltransferase 10C, mitochondrial RNase P subunit" Q7L0Y3 3 101561862-101566446 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036671 Approved Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA036671: AB_10602085" "unprognostic (7.42e-2)" "unprognostic (2.68e-1)" "unprognostic (9.08e-3)" "unprognostic (4.47e-3)" "unprognostic (5.01e-2)" "unprognostic (5.55e-2)" "prognostic unfavourable (6.56e-5)" "unprognostic (1.67e-2)" "unprognostic (8.48e-2)" "unprognostic (5.42e-2)" "unprognostic (4.70e-2)" "unprognostic (3.28e-2)" "prognostic favourable (3.32e-5)" "unprognostic (2.77e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" 18.0 21.2 13.1 13.6 14.1 14.4 19.7 16.4 19.1 16.1 15.3 5.5 12.9 11.6 14.6 13.1 20.9 15.0 10.7 20.4 13.0 13.4 26.6 34.6 10.0 19.3 12.5 16.7 18.8 12.1 9.9 19.9 18.2 18.5 16.2 14.2 5.5 14.5 13.0 35.2 15.2 16.5 15.3 14.3 19.6 15.6 14.7 10.6 23.0 16.6 30.5 18.5 15.6 11.3 21.6 15.4 27.4 14.8 12.2 23.1 11.8 20.8 10.2 13.6 13.7 12.5 10.7 12.7 12.4 12.2 16.3 18.2 15.5 14.1 43.4 16.3 7.7 21.1 26.2 19.0 22.4 15.5 12.9 29.1 8.1 11.2 9.6 25.5 12.4 12.5 19.8 14.2 13.3 15.8 24.6 9.7 17.5 14.3 20.4 18.7 25.2 22.1 15.2 11.1 19.4 20.8 17.7 33.9 19.4 9.7 20.7 27.4 27.3 28.2 10.4 8.9 16.8 5.9 13.1 11.3 20.6 41.6 15.0 18.4 13.3 27.4 11.2 7.3 13.6 14.4 18.8 21.6 16.8 15.8 13.5 20.4 23.1 21.1 4.9 12.2 14.8 15.4 15.0 11.8 13.1 14.1 16.4 19.1 13.0 13.4 12.5 16.7 18.5 10.6 TRMT12 "FLJ20772, Trm12, TYW2" ENSG00000183665 "TRNA methyltransferase 12 homolog" Q53H54 8 124450820-124462150 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023939 Approved Approved Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA023939: AB_1848793" "unprognostic (2.54e-2)" "unprognostic (2.20e-1)" "unprognostic (7.81e-2)" "unprognostic (1.02e-2)" "unprognostic (8.75e-2)" "prognostic unfavourable (2.99e-5)" "prognostic unfavourable (5.10e-4)" "unprognostic (6.89e-2)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" "unprognostic (6.56e-2)" "unprognostic (4.72e-3)" "unprognostic (3.39e-2)" "unprognostic (2.40e-1)" "prognostic unfavourable (9.25e-4)" "unprognostic (1.04e-2)" 10.8 11.6 16.7 8.4 20.9 4.1 15.0 13.8 18.3 11.8 9.5 8.0 6.8 7.5 11.9 10.7 9.6 13.2 8.6 9.9 19.4 9.9 12.9 9.8 9.8 11.8 13.6 14.3 8.8 10.1 14.7 17.7 8.9 14.7 12.0 11.2 7.8 12.0 11.0 18.0 9.9 9.6 14.3 12.9 11.0 10.6 11.7 13.4 9.1 14.9 12.0 10.7 10.2 8.5 5.8 5.0 6.3 6.1 5.1 7.6 4.4 7.4 6.5 5.4 4.2 10.3 5.3 1.3 4.7 5.5 7.0 6.0 3.9 5.2 7.6 6.5 4.8 5.2 7.7 7.7 8.3 7.5 5.8 7.3 6.2 1.3 8.1 0.0 5.9 6.5 10.4 6.8 8.7 5.8 10.2 5.3 4.3 37.1 8.5 3.1 0.0 6.0 2.7 3.6 5.0 6.4 8.1 9.2 7.3 6.9 26.1 9.7 7.4 3.1 4.6 4.8 12.7 3.6 5.3 5.5 7.7 2.9 4.4 2.6 3.9 0.5 6.1 6.3 4.5 4.9 5.6 4.0 6.1 4.6 5.0 5.8 7.6 7.4 2.4 5.1 5.5 1.5 3.7 4.4 16.7 20.9 13.8 18.3 19.4 9.9 13.6 14.3 14.7 13.4 TRMT13 "CCDC76, FLJ10287, FLJ11219" ENSG00000122435 "TRNA methyltransferase 13 homolog" Q9NUP7 1 100133150-100150497 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028494 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane" "Nuclear bodies, Cytosol" "HPA028494: AB_10601254" "unprognostic (1.12e-1)" "unprognostic (3.33e-1)" "unprognostic (5.76e-2)" "unprognostic (2.37e-1)" "unprognostic (9.17e-3)" "unprognostic (4.97e-2)" "prognostic unfavourable (5.81e-5)" "unprognostic (1.16e-3)" "unprognostic (3.28e-2)" "unprognostic (8.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" "prognostic unfavourable (6.89e-6)" "unprognostic (3.12e-2)" "unprognostic (7.71e-2)" "unprognostic (1.99e-2)" "unprognostic (1.70e-3)" 13.0 12.2 13.9 21.7 24.1 5.9 18.3 26.5 22.5 17.4 13.1 18.2 24.2 13.6 17.4 15.4 13.7 13.9 9.6 12.0 14.4 9.0 12.1 13.0 9.6 20.9 23.1 12.8 21.4 18.1 23.8 26.8 13.2 15.6 14.9 14.4 10.8 14.3 17.4 16.9 17.9 14.2 14.3 19.4 16.5 12.6 11.1 25.8 17.8 16.5 12.0 17.6 13.9 15.8 15.1 9.6 2.2 4.5 5.4 13.6 3.9 10.6 6.2 10.5 7.3 5.7 11.2 11.5 11.3 4.5 8.6 7.2 7.4 4.4 17.6 14.1 9.0 9.7 19.3 8.7 15.0 17.7 15.3 10.5 13.8 7.1 10.3 18.1 9.9 7.8 10.0 16.3 21.5 7.8 22.0 11.4 8.6 4.0 14.8 9.6 14.6 12.6 15.9 15.9 9.6 7.1 8.5 6.9 11.5 10.4 10.0 13.3 5.9 16.1 8.1 11.5 7.7 9.6 15.0 14.6 11.8 20.9 13.0 14.6 4.4 0.1 4.5 2.2 8.5 4.4 10.4 14.8 9.0 8.3 5.2 15.1 13.6 11.1 1.9 5.4 3.5 9.6 6.2 3.9 13.9 24.1 26.5 22.5 14.4 9.0 23.1 12.8 15.6 25.8 TRMT2B "CXorf34, FLJ12687" ENSG00000188917 "TRNA methyltransferase 2 homolog B" Q96GJ1 X 101009346-101052116 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003745, HPA035120, HPA040814" Uncertain Approved "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA003745: , HPA035120: AB_10601702, HPA040814: " "prognostic unfavourable (1.58e-5)" "unprognostic (6.72e-3)" "unprognostic (3.28e-1)" "unprognostic (1.54e-2)" "unprognostic (4.44e-1)" "unprognostic (8.74e-2)" "unprognostic (3.52e-2)" "unprognostic (8.16e-3)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (8.80e-2)" "unprognostic (2.78e-2)" "prognostic favourable (2.30e-7)" "unprognostic (4.58e-2)" "unprognostic (4.82e-1)" "unprognostic (5.03e-2)" "unprognostic (1.60e-2)" 7.6 10.4 6.9 8.9 10.3 9.1 8.5 7.0 14.2 9.6 11.4 6.9 10.7 8.1 8.1 8.6 12.9 7.4 7.3 13.0 10.7 6.6 12.3 9.5 9.4 12.6 9.5 6.6 11.3 10.4 18.5 17.6 5.9 10.7 10.1 12.6 13.4 15.3 10.4 17.6 9.5 13.5 7.9 8.4 16.6 11.4 4.0 7.9 18.2 12.8 5.3 17.7 9.9 9.5 16.5 8.1 14.8 8.2 14.4 19.2 11.5 15.6 13.6 2.8 6.4 6.4 3.4 8.6 8.1 11.0 9.2 13.7 14.6 12.5 13.9 16.3 7.5 9.8 12.5 11.3 11.5 12.0 7.9 8.8 11.2 6.9 5.7 15.6 14.4 4.3 6.7 13.2 6.1 17.6 9.0 13.3 8.4 15.8 19.4 8.3 3.8 10.1 15.9 13.4 13.3 6.7 9.3 4.1 5.4 13.9 10.1 8.1 6.6 7.5 10.3 11.6 7.0 10.8 7.2 8.5 12.7 13.0 9.0 18.0 8.9 9.6 8.2 14.8 13.8 6.5 14.6 14.9 16.1 13.3 7.4 16.5 19.2 16.1 4.8 14.4 7.0 8.1 13.0 11.5 6.9 10.3 7.0 14.2 10.7 6.6 9.5 6.6 10.7 7.9 TRMT44 "C4orf23, FLJ35725, METTL19, TRM44" ENSG00000155275 "TRNA methyltransferase 44 homolog" Q8IYL2 4 8436140-8493531 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045461 Uncertain Approved Nucleoplasm Nucleoplasm "HPA045461: AB_10961276" "unprognostic (1.50e-1)" "unprognostic (1.65e-3)" "unprognostic (3.47e-1)" "unprognostic (1.01e-2)" "unprognostic (2.06e-1)" "unprognostic (1.34e-2)" "unprognostic (1.75e-1)" "unprognostic (1.78e-2)" "unprognostic (3.46e-1)" "unprognostic (8.13e-2)" "unprognostic (3.44e-3)" "unprognostic (2.69e-3)" "unprognostic (1.49e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (6.76e-2)" "unprognostic (8.34e-3)" 11.5 7.6 13.3 7.3 17.5 13.1 15.4 20.3 16.2 10.1 9.2 14.1 10.1 7.1 16.3 10.7 13.6 12.3 8.6 9.8 12.1 6.3 7.1 8.9 8.8 9.8 12.2 14.7 17.1 9.7 11.3 10.9 10.2 8.7 10.8 7.2 9.4 12.4 8.7 11.5 17.2 7.6 9.7 6.7 8.1 11.3 15.8 13.8 7.8 9.9 9.0 10.7 10.8 11.4 2.1 2.1 0.4 2.1 0.8 3.0 0.5 5.5 5.8 7.3 8.6 7.8 7.6 15.9 6.6 4.7 8.8 7.9 7.1 7.9 7.6 3.2 2.6 4.3 10.6 6.5 7.7 3.8 5.2 7.1 9.1 5.6 6.7 12.2 5.9 4.6 8.9 6.7 7.3 9.3 10.8 8.2 5.5 3.6 10.1 8.9 8.3 8.8 7.5 7.8 4.8 7.5 6.7 8.0 5.5 4.3 3.9 5.8 3.5 4.7 5.5 5.4 3.0 5.0 10.1 9.6 6.0 7.0 5.9 11.4 5.2 0.4 1.2 0.1 2.3 1.2 1.6 0.8 2.1 2.5 2.1 2.1 3.0 0.9 0.2 0.8 2.1 1.7 0.2 0.5 13.3 17.5 20.3 16.2 12.1 6.3 12.2 14.7 8.7 13.8 TRMT5 "KIAA1393, TRM5" ENSG00000126814 "TRNA methyltransferase 5" Q32P41 14 60971451-60981358 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000943 Supported Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA000943: AB_1080388" "unprognostic (1.58e-2)" "unprognostic (3.62e-2)" "unprognostic (6.63e-3)" "unprognostic (1.11e-2)" "unprognostic (7.70e-3)" "unprognostic (2.26e-2)" "unprognostic (7.82e-3)" "unprognostic (4.50e-2)" "unprognostic (3.95e-1)" "unprognostic (1.78e-1)" "unprognostic (1.47e-1)" "unprognostic (2.84e-2)" "unprognostic (1.60e-3)" "unprognostic (1.82e-1)" "unprognostic (1.97e-2)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" 15.8 10.1 7.9 13.8 12.1 5.4 12.9 9.3 11.8 10.9 8.6 5.7 11.9 7.5 12.0 10.9 11.1 10.0 6.7 6.8 7.7 7.1 12.5 13.9 6.6 7.3 6.7 8.3 17.1 11.1 15.9 13.1 10.8 9.0 10.6 8.1 4.8 11.5 9.9 14.8 9.7 7.4 9.2 6.3 8.6 8.1 24.9 5.9 12.4 10.4 12.1 7.2 13.3 9.0 7.2 7.4 0.9 7.5 2.0 6.0 3.7 28.3 7.3 10.7 14.9 9.4 14.2 11.7 10.7 8.2 11.5 9.1 5.3 17.0 14.6 11.9 7.7 13.1 13.4 15.4 15.1 14.4 6.8 10.7 4.9 5.9 15.4 18.9 6.0 11.2 15.0 10.4 15.4 10.0 13.9 5.2 16.8 10.7 9.7 9.5 9.8 12.0 3.1 24.8 12.3 9.7 9.6 13.1 13.0 11.9 11.9 9.4 19.9 11.4 9.4 13.3 16.1 9.4 10.1 3.2 6.0 6.9 9.3 4.1 12.4 0.1 4.6 0.9 3.5 7.5 5.0 7.2 5.2 5.2 4.2 4.9 5.6 5.1 0.4 2.0 7.5 7.4 6.0 3.7 7.9 12.1 9.3 11.8 7.7 7.1 6.7 8.3 9.0 5.9 TRMT61B FLJ20628 ENSG00000171103 "TRNA methyltransferase 61B" Q9BVS5 2 28849821-28870301 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026747, HPA026751" Enhanced Uncertain Cytosol Cytosol "HPA026747: AB_1848782, HPA026751: AB_1848784" "unprognostic (1.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.63e-3)" "unprognostic (2.05e-2)" "unprognostic (3.32e-2)" "unprognostic (4.14e-2)" "prognostic unfavourable (3.61e-4)" "unprognostic (2.36e-2)" "unprognostic (2.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.52e-2)" "unprognostic (2.52e-2)" "prognostic favourable (9.61e-5)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (5.38e-2)" "unprognostic (2.34e-1)" 11.6 19.5 20.4 12.8 22.5 10.9 18.5 33.7 21.0 13.8 11.7 17.4 10.9 19.2 15.6 20.4 12.6 11.8 10.1 16.3 17.2 18.4 19.8 16.9 9.0 13.8 17.0 15.6 13.7 10.0 21.1 25.4 12.2 17.8 15.2 13.2 14.2 12.6 11.8 17.9 11.9 18.6 14.4 14.7 13.2 12.4 14.6 18.7 12.6 12.8 10.4 14.5 14.8 10.8 11.9 6.8 2.7 7.0 13.9 12.4 6.3 17.8 10.8 10.9 19.3 15.0 12.9 13.2 10.6 13.2 13.6 12.8 12.3 9.7 19.0 9.8 9.3 14.0 15.2 12.9 14.1 14.2 10.3 5.8 8.9 16.1 17.0 12.2 6.6 13.1 14.5 10.8 14.8 13.0 11.7 7.3 11.2 7.1 10.7 18.5 20.3 17.3 8.0 17.7 16.3 11.9 11.6 18.6 19.7 11.5 18.2 17.5 9.3 4.3 10.1 9.1 15.3 8.9 13.3 9.1 14.9 29.4 12.1 18.4 12.2 0.0 6.6 2.7 9.8 7.0 12.1 11.9 11.1 10.5 6.4 11.6 12.4 8.9 0.9 13.9 5.7 6.8 11.6 6.3 20.4 22.5 33.7 21.0 17.2 18.4 17.0 15.6 17.8 18.7 TRMU "FLJ10140, MTO2, TRMT" ENSG00000100416 "TRNA 5-methylaminomethyl-2-thiouridylate methyltransferase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000824, HPA035273, HPA043300" Uncertain Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA000824: , HPA035273: AB_10602901, HPA043300: " "unprognostic (2.96e-1)" "unprognostic (1.09e-2)" "unprognostic (8.07e-2)" "unprognostic (4.27e-2)" "unprognostic (2.64e-1)" "unprognostic (3.52e-3)" "prognostic unfavourable (3.04e-5)" "unprognostic (4.72e-2)" "unprognostic (7.14e-2)" "unprognostic (7.89e-2)" "prognostic favourable (6.86e-4)" "unprognostic (4.74e-3)" "prognostic unfavourable (5.63e-6)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (7.44e-3)" 8.5 16.1 11.5 9.9 16.0 6.4 7.5 17.8 16.0 9.7 8.7 11.5 10.2 10.9 12.1 18.0 10.9 6.2 7.3 16.8 11.3 11.9 20.5 18.8 7.1 10.2 15.7 11.8 8.0 22.7 20.0 13.6 9.7 11.2 8.7 10.2 9.0 12.5 15.5 17.8 9.8 7.6 9.4 11.4 8.7 9.2 8.3 13.9 6.5 9.6 8.3 9.8 7.1 9.1 6.2 7.6 3.9 9.6 7.5 11.3 6.3 10.8 9.9 4.3 9.6 8.0 5.7 10.7 11.3 8.0 16.1 12.5 14.0 2.7 7.1 8.0 10.1 9.7 18.1 10.1 13.8 4.6 24.4 8.4 15.2 16.5 6.9 16.1 5.8 5.4 11.4 16.6 5.3 10.3 11.7 1.7 9.7 11.4 6.2 13.2 16.1 17.5 7.4 9.2 13.1 8.0 7.5 10.2 12.3 10.0 11.8 18.9 6.7 6.7 7.5 7.2 12.8 10.1 12.6 4.2 4.5 7.6 10.1 11.7 14.4 0.0 6.8 3.9 11.1 9.4 9.4 5.7 9.4 10.0 7.6 6.2 8.6 8.0 1.4 7.5 9.6 6.0 11.3 6.3 11.5 16.0 17.8 16.0 11.3 11.9 15.7 11.8 11.2 13.9 TRNT1 "CCA1, CGI-47, MtCCA" ENSG00000072756 "TRNA nucleotidyl transferase 1" Q96Q11 3 3126916-3150879 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036938 Uncertain Supported Mitochondria Mitochondria "HPA036938: AB_10670566" "unprognostic (6.39e-3)" "unprognostic (1.58e-1)" "unprognostic (2.38e-3)" "unprognostic (4.69e-2)" "unprognostic (4.92e-2)" "unprognostic (2.41e-1)" "unprognostic (1.39e-2)" "unprognostic (2.68e-1)" "unprognostic (6.22e-2)" "unprognostic (5.65e-2)" "unprognostic (4.62e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-2)" "unprognostic (6.50e-2)" "unprognostic (1.09e-1)" "unprognostic (3.78e-1)" "unprognostic (1.02e-1)" 15.2 16.9 17.5 17.8 20.7 8.7 18.2 14.5 22.7 12.9 13.2 13.2 17.4 11.1 18.4 14.7 15.9 12.2 15.6 13.9 17.1 16.0 21.1 16.1 13.7 19.0 17.5 15.6 14.6 13.9 14.3 31.0 19.0 21.3 23.9 16.4 10.1 13.2 13.1 14.8 15.3 12.5 15.3 19.3 20.5 15.5 13.5 15.1 22.1 20.9 10.6 19.8 17.8 13.0 15.1 10.5 29.0 12.0 15.1 16.6 7.4 11.9 17.3 13.4 7.6 16.0 13.7 14.3 13.7 11.4 13.7 14.2 16.0 14.7 21.8 9.1 13.2 8.6 17.7 12.4 17.5 16.2 8.5 20.3 18.4 16.0 21.4 21.4 16.5 12.8 17.5 14.1 4.8 13.5 15.7 9.2 23.6 22.3 13.8 19.4 10.6 12.6 13.2 18.1 21.2 18.3 17.8 7.7 11.0 19.8 14.4 11.4 13.3 12.2 11.0 15.5 13.5 16.0 17.5 9.4 18.8 27.5 11.6 19.3 17.2 29.0 8.8 22.5 12.1 11.8 11.9 15.1 15.0 12.7 10.5 9.5 16.6 14.3 11.7 15.1 12.0 9.6 11.1 7.4 17.5 20.7 14.5 22.7 17.1 16.0 17.5 15.6 21.3 15.1 TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686815 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 91.8" "Cell line enhanced" "Detected in all" "U-2197: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" "Plasma membrane" "Vesicles, Cytosol" "HPA035522: , HPA052173: " "unprognostic (3.14e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.60e-2)" "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (2.91e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (7.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.97e-1)" 13.3 10.8 6.6 14.7 9.0 12.8 12.1 19.5 9.3 11.8 11.7 8.1 9.7 9.9 16.5 10.7 9.4 11.0 8.2 19.1 5.5 4.9 16.0 20.0 10.8 10.6 12.4 5.2 16.6 11.6 91.8 14.6 14.3 10.2 9.7 10.3 28.6 11.5 13.5 10.8 11.7 12.8 12.8 9.8 11.1 10.3 6.9 10.0 14.5 12.6 6.9 12.6 12.9 12.3 7.0 4.7 4.4 3.4 5.7 7.6 2.0 8.3 8.3 7.0 7.7 20.2 15.2 8.5 10.6 14.7 6.7 8.9 11.4 4.6 18.2 5.2 12.2 14.1 9.3 7.8 9.7 10.1 5.6 14.5 12.8 6.0 18.4 15.0 11.3 14.1 9.2 7.6 14.4 5.4 16.4 14.0 12.2 13.1 9.6 7.3 5.3 5.1 10.6 9.7 8.9 9.4 19.8 5.8 7.4 7.3 11.6 14.2 7.3 16.3 8.2 10.7 5.1 49.9 12.1 9.5 21.0 17.5 11.7 30.7 9.9 3.8 3.4 3.9 6.6 3.2 7.6 5.6 4.8 4.4 3.7 7.0 4.4 5.2 4.4 5.7 3.2 4.7 4.8 2.0 6.6 9.0 19.5 9.3 5.5 4.9 12.4 5.2 10.2 10.0 TRPT1 MGC11134 ENSG00000149743 "TRNA phosphotransferase 1" Q86TN4 11 64223799-64226254 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038705, HPA038706" Uncertain Approved Mitochondria Mitochondria "HPA038705: , HPA038706: AB_10671863" "unprognostic (2.50e-2)" "unprognostic (1.72e-1)" "unprognostic (1.33e-1)" "unprognostic (3.59e-2)" "unprognostic (7.20e-2)" "unprognostic (1.53e-1)" "unprognostic (5.84e-2)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-3)" "unprognostic (1.12e-1)" "unprognostic (7.71e-2)" "unprognostic (7.38e-2)" "unprognostic (2.49e-1)" "unprognostic (3.28e-1)" "unprognostic (1.99e-1)" "unprognostic (4.58e-3)" 8.1 12.2 10.8 11.1 12.6 4.4 9.1 6.4 12.1 8.8 15.1 10.9 37.4 12.5 7.8 15.3 13.3 10.4 13.5 34.4 10.9 10.3 16.9 13.7 7.0 8.3 13.6 8.5 8.7 23.3 9.1 11.6 8.5 10.8 11.3 10.8 9.9 22.3 33.5 58.8 10.8 13.1 7.0 10.1 10.3 12.2 18.9 10.3 17.2 13.3 23.9 13.2 11.9 7.7 22.9 31.7 14.5 16.2 12.4 13.2 6.5 10.7 10.7 11.9 19.1 14.8 10.8 14.7 7.2 14.1 12.9 10.9 7.0 16.4 10.9 29.3 11.9 15.1 5.2 15.7 4.5 10.5 6.4 5.5 10.8 12.1 21.4 6.9 9.8 8.1 9.2 14.3 12.7 9.0 9.6 12.1 10.7 25.5 12.8 14.8 7.6 11.9 16.9 8.9 30.7 33.1 12.9 10.5 15.3 5.8 14.3 21.1 16.6 11.2 10.5 8.9 6.8 17.2 7.1 24.4 6.0 6.9 21.3 3.6 14.2 6.0 9.4 14.5 10.9 16.2 8.4 20.8 10.5 11.2 13.0 22.9 11.9 13.2 8.3 12.4 13.9 31.7 13.2 6.5 10.8 12.6 6.4 12.1 10.9 10.3 13.6 8.5 10.8 10.3 TSEN2 "MGC2776, SEN2, SEN2L" ENSG00000154743 "TRNA splicing endonuclease subunit 2" Q8NCE0 3 12484432-12539623 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027120, HPA027125, HPA027268" Approved Supported Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA027120: AB_10600197, HPA027125: AB_10601896, HPA027268: AB_10601347" "unprognostic (5.58e-2)" "unprognostic (4.49e-1)" "unprognostic (1.49e-1)" "unprognostic (3.71e-2)" "unprognostic (9.59e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (1.13e-5)" "unprognostic (1.42e-1)" "unprognostic (5.66e-2)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "unprognostic (6.15e-2)" "unprognostic (1.41e-2)" "unprognostic (6.99e-2)" "unprognostic (4.90e-2)" "unprognostic (6.06e-2)" "prognostic favourable (3.49e-4)" 8.8 10.6 9.7 8.8 19.1 6.7 10.9 16.5 14.0 10.4 9.8 12.7 8.4 5.8 14.0 9.9 7.9 12.8 10.3 14.3 10.5 12.3 9.8 7.3 7.3 10.9 11.5 7.6 18.0 11.9 14.3 15.3 4.9 10.2 10.5 10.9 13.5 7.2 13.1 16.7 15.3 6.1 12.3 12.3 6.1 8.5 11.3 9.1 9.9 12.5 9.6 8.1 8.6 8.3 8.5 7.1 2.6 4.2 5.0 13.7 5.6 8.0 14.0 7.5 9.9 12.8 13.6 17.4 7.6 6.7 8.1 5.9 7.9 8.6 9.7 5.3 6.2 7.5 12.5 13.0 9.3 7.6 15.6 10.6 18.8 8.1 9.9 16.6 4.1 11.7 15.1 14.8 18.2 6.5 15.6 5.3 9.4 15.1 12.6 7.6 10.6 16.9 9.6 5.2 19.3 12.2 8.2 4.9 8.6 7.0 6.3 5.9 11.4 11.6 5.8 5.2 5.1 7.1 11.7 5.0 12.7 12.0 7.0 16.7 6.5 2.4 4.2 0.3 6.4 4.2 10.9 8.5 9.8 7.4 5.9 8.3 13.7 11.7 2.6 5.0 3.6 7.1 3.5 5.6 9.7 19.1 16.5 14.0 10.5 12.3 11.5 7.6 10.2 9.1 TSEN34 "LENG5, SEN34, SEN34L" ENSG00000170892 "TRNA splicing endonuclease subunit 34" Q9BSV6 19 54189938-54194536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Disease mutation, Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 24.8" "Group enriched" "Detected in many" 6 "granulocytes: 24.8;monocytes: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041111, HPA048208" Approved Supported Nucleoplasm Nucleoplasm "HPA041111: AB_10794263, HPA048208: " "unprognostic (3.24e-2)" "unprognostic (2.95e-2)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (3.48e-2)" "unprognostic (4.82e-2)" "prognostic unfavourable (1.44e-7)" "unprognostic (2.38e-1)" "unprognostic (7.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.04e-3)" "unprognostic (8.98e-2)" "unprognostic (4.55e-3)" "unprognostic (2.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.81e-1)" "unprognostic (1.12e-1)" 12.3 28.0 10.4 10.8 10.2 8.2 15.4 4.0 12.8 19.8 19.5 9.4 19.2 3.0 17.3 23.4 20.2 25.3 18.1 20.0 8.8 9.8 15.4 20.0 13.4 18.2 8.7 8.9 31.8 27.3 19.2 14.3 22.0 8.7 23.2 12.3 15.7 17.8 29.5 15.7 14.7 9.8 18.6 7.8 18.0 13.0 27.3 7.7 12.9 28.5 19.6 14.9 19.8 15.5 1.4 2.6 24.8 8.1 0.8 2.4 1.5 28.9 4.2 11.8 16.8 7.0 14.3 12.8 3.6 7.3 8.8 8.2 2.1 4.2 2.2 1.0 5.6 20.4 16.0 21.3 6.4 7.5 24.4 2.6 0.8 2.3 6.7 0.7 3.6 22.9 9.8 6.0 7.1 17.9 5.8 1.3 18.6 3.5 1.5 0.0 2.7 3.1 7.3 8.0 1.0 25.2 2.5 0.6 6.8 0.8 21.6 8.0 17.1 2.1 1.2 0.0 12.2 12.6 22.2 8.2 7.9 2.0 21.1 1.3 13.4 4.1 8.1 17.8 0.9 3.3 1.8 1.0 1.3 2.4 2.3 1.4 2.3 0.9 24.8 0.8 5.2 2.6 0.7 1.5 10.4 10.2 4.0 12.8 8.8 9.8 8.7 8.9 8.7 7.7 TSSK1B "FKSG81, SPOGA4, STK22D, TSSK1" ENSG00000212122 "Testis specific serine kinase 1B" Q9BXA7 5 113432554-113435031 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "testis: 59.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.3;EFO-21: 2.1;RT4: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA027827 Enhanced "HPA027827: AB_10603138" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.6 0.1 0.2 0.0 1.0 0.0 0.0 0.0 0.2 0.0 1.3 0.2 2.1 0.0 0.4 0.2 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.5 0.1 0.0 0.1 0.3 0.0 0.4 0.0 0.5 0.2 0.2 0.3 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSSK3 "SPOGA3, STK22C" ENSG00000162526 "Testis specific serine kinase 3" Q96PN8 1 32351521-32364312 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 68.1" "Cell line enhanced" "Detected in many" "HeLa: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA037516 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA037516: " "unprognostic (5.71e-2)" "unprognostic (1.42e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-1)" "unprognostic (7.69e-2)" "unprognostic (2.02e-4)" "unprognostic (2.06e-1)" "unprognostic (1.98e-3)" "unprognostic (2.05e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (9.20e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.68e-3)" 1.1 2.0 0.8 1.7 0.8 8.2 1.1 3.9 0.8 1.3 0.9 0.8 1.4 2.5 1.8 2.9 0.8 1.3 1.0 0.9 0.8 0.0 0.9 1.3 1.4 2.4 0.8 0.8 2.0 1.2 0.0 0.8 0.8 1.0 1.0 0.0 0.8 1.4 0.8 1.7 3.4 2.9 0.8 0.8 3.4 1.2 68.1 0.8 0.8 1.3 0.8 0.8 0.9 1.1 0.6 0.1 0.1 0.7 0.3 2.3 0.1 2.3 2.3 6.0 3.6 0.0 1.2 5.4 0.7 1.1 0.0 0.0 0.5 1.2 1.2 0.9 0.0 3.7 0.0 0.0 0.0 3.5 7.2 2.7 9.8 3.7 4.4 1.1 3.4 0.1 0.9 0.0 1.3 0.0 3.1 5.8 0.0 0.6 1.4 1.5 1.5 1.2 1.9 1.7 4.4 0.0 1.9 1.8 3.8 0.8 2.8 4.1 1.9 2.7 2.9 2.1 3.4 3.0 2.4 8.5 2.8 1.8 3.7 3.9 0.5 0.0 0.1 0.0 1.1 0.7 0.0 0.0 0.2 0.0 0.1 0.6 2.3 0.9 0.1 0.3 0.5 0.0 0.0 0.1 0.8 0.8 3.9 0.8 0.8 0.0 0.8 0.8 1.0 0.8 TSSK4 "C14orf20, STK22E" ENSG00000139908 "Testis specific serine kinase 4" Q6SA08 14 24205697-24208362 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 46.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060660, HPA077103" Approved Approved "Cell Junctions" "Cell Junctions" "HPA060660: , HPA077103: " "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.52e-1)" "unprognostic (5.69e-2)" "unprognostic (2.36e-1)" "unprognostic (3.38e-5)" "unprognostic (1.06e-1)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (3.39e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-3)" "unprognostic (3.42e-1)" "unprognostic (4.30e-2)" "unprognostic (6.28e-2)" "unprognostic (8.98e-2)" "unprognostic (7.26e-2)" 0.6 0.9 0.6 1.7 0.6 3.1 0.6 1.5 1.8 0.6 0.6 0.6 0.6 1.5 0.8 0.9 1.4 0.8 1.7 0.6 0.6 0.4 0.6 0.6 0.8 2.8 0.6 0.6 0.8 0.9 0.0 0.6 0.6 0.6 0.6 0.0 0.6 1.4 0.6 1.0 4.7 1.6 0.6 0.6 1.5 0.6 46.1 0.6 0.6 1.4 0.6 0.6 1.0 0.6 2.1 1.7 2.0 1.0 1.8 2.0 0.7 1.0 4.0 3.9 1.5 0.1 0.0 4.3 1.6 0.1 0.0 0.0 2.1 3.7 3.1 0.9 0.1 3.8 0.0 0.1 0.0 1.6 3.0 3.4 4.8 3.0 0.0 1.5 3.7 0.0 0.0 0.0 0.6 0.1 1.3 2.0 0.0 3.8 3.6 1.6 0.7 3.2 2.9 1.5 2.6 0.0 5.2 2.2 2.0 2.7 2.5 0.8 1.6 1.7 1.4 2.9 1.8 3.7 1.3 4.2 4.8 4.7 1.0 2.8 0.9 0.0 1.0 2.0 2.0 1.0 0.7 2.0 1.6 1.6 0.6 2.1 1.6 1.7 2.0 1.8 0.9 1.7 0.7 0.7 0.6 0.6 1.5 0.6 0.6 0.4 0.6 0.6 0.6 0.6 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 102.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 16.0" "Group enriched" "Detected in all" 6 "dendritic cells: 16.0;granulocytes: 14.3;monocytes: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria 2800000 Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favourable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favourable (1.04e-4)" 8.5 29.7 6.0 13.5 7.6 5.7 6.1 5.0 10.5 9.5 38.4 12.9 10.9 37.4 5.9 4.0 16.6 6.8 38.4 14.1 5.1 4.9 19.7 102.1 6.2 3.2 8.2 7.0 7.2 23.9 1.8 2.3 5.0 5.9 8.1 21.6 6.2 13.6 6.9 8.3 5.4 39.5 3.8 4.7 3.5 22.8 3.3 6.7 1.8 8.5 12.8 10.5 7.2 9.2 1.6 16.0 14.3 11.5 2.2 1.2 5.2 15.1 33.7 4.3 14.4 10.4 4.1 8.0 8.4 7.2 4.9 7.4 9.8 10.0 4.0 7.1 6.6 13.1 3.1 8.4 1.1 11.7 18.9 4.2 6.4 19.0 26.1 5.8 10.0 8.0 9.6 3.6 3.1 12.0 5.0 7.0 2.3 34.7 0.2 18.8 7.3 14.8 13.6 4.6 7.0 13.8 14.2 2.5 6.5 8.9 16.0 11.4 16.5 14.8 9.0 5.6 10.5 9.3 2.6 5.3 5.3 1.2 2.0 16.9 3.3 5.3 11.5 4.9 0.6 3.0 1.1 1.6 0.5 0.4 16.0 0.8 0.3 0.2 14.3 2.2 0.8 1.1 1.2 5.2 6.0 7.6 5.0 10.5 5.1 4.9 8.2 7.0 5.9 6.7 TSTA3 "FX, P35B, SDR4E1" ENSG00000104522 "Tissue specific transplantation antigen P35B" Q13630 8 143612618-143618048 "Enzymes, Predicted intracellular proteins" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023361 Approved Approved Nucleoplasm,Cytosol 600000 Cytosol Nucleoplasm "HPA023361: AB_1858420" "unprognostic (1.37e-2)" "unprognostic (5.35e-2)" "unprognostic (8.62e-3)" "unprognostic (3.55e-2)" "unprognostic (2.90e-1)" "unprognostic (5.82e-2)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (8.62e-2)" "prognostic favourable (2.41e-4)" "unprognostic (6.62e-3)" "unprognostic (6.89e-2)" "prognostic unfavourable (1.59e-4)" "unprognostic (4.23e-2)" "unprognostic (2.78e-2)" "unprognostic (1.87e-2)" "unprognostic (3.27e-2)" 9.4 12.0 7.0 9.5 10.1 16.3 10.2 6.1 13.8 8.6 18.7 8.4 16.6 24.8 8.4 9.9 28.0 7.7 23.7 15.7 8.1 7.8 11.7 40.0 8.9 16.5 6.8 8.1 9.7 60.1 6.4 14.2 21.9 12.2 13.9 14.9 9.5 35.4 14.2 16.8 28.4 20.2 6.9 4.7 11.3 35.5 24.6 5.6 14.7 13.0 17.8 24.8 9.8 10.4 18.7 25.6 17.7 21.0 28.1 26.9 20.5 17.5 12.8 6.5 19.3 5.4 5.2 12.0 14.6 14.3 10.4 7.8 15.7 18.8 7.7 14.3 10.3 12.6 9.7 19.8 4.7 19.9 14.1 11.4 22.7 18.1 11.1 7.6 13.0 6.5 10.2 7.0 25.0 16.8 12.6 11.2 7.8 53.3 9.9 11.5 8.8 17.6 11.3 4.9 23.7 20.9 17.6 13.3 10.4 10.0 19.7 14.6 25.0 11.1 14.1 6.9 27.4 8.2 14.0 8.4 6.0 5.6 10.6 17.4 10.3 10.5 15.9 17.7 21.0 21.0 21.2 16.1 22.7 22.6 18.0 18.7 16.9 18.7 16.3 28.1 16.3 25.6 26.9 20.5 7.0 10.1 6.1 13.8 8.1 7.8 6.8 8.1 12.2 5.6 TTBK1 KIAA1855 ENSG00000146216 "Tau tubulin kinase 1" Q5TCY1 6 43243680-43288259 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9" "Group enriched" "Detected in some" 9 "SCLC-21H: 20.8;SH-SY5Y: 7.9" "Cancer enhanced" "Detected in some" "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031735, HPA031736" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA031735: , HPA031736: AB_10670294" "unprognostic (1.68e-1)" "unprognostic (7.88e-3)" "unprognostic (7.01e-2)" "unprognostic (1.62e-3)" "unprognostic (2.18e-1)" "unprognostic (2.24e-4)" "unprognostic (2.46e-3)" "unprognostic (3.01e-2)" "unprognostic (3.09e-1)" "unprognostic (1.85e-1)" "unprognostic (3.01e-2)" "unprognostic (2.12e-4)" "unprognostic (7.42e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (2.64e-3)" "unprognostic (3.04e-4)" 1.1 3.9 12.4 1.3 12.9 0.9 1.0 14.9 28.9 1.0 1.4 8.2 0.0 4.6 1.0 1.0 1.0 1.1 1.4 1.3 10.3 7.5 1.7 3.5 1.1 1.2 7.1 12.5 1.0 1.4 1.6 7.7 1.0 9.0 1.3 1.3 0.7 1.0 1.2 1.0 1.0 6.8 1.1 6.2 1.2 1.3 2.3 8.3 0.0 1.0 0.0 1.3 1.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 20.8 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 12.4 12.9 14.9 21.7 10.3 7.5 7.1 12.5 9.0 8.3 TTBK2 "KIAA0847, SCA11" ENSG00000128881 "Tau tubulin kinase 2" Q6IQ55 15 42738734-42920809 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018113, HPA049866" Approved Uncertain "Intermediate filaments" "Intermediate filaments" "HPA018113: AB_1858421, HPA049866: " "unprognostic (2.15e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-1)" "unprognostic (6.30e-2)" "unprognostic (7.73e-2)" "unprognostic (4.26e-1)" "unprognostic (6.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (2.78e-2)" "unprognostic (8.62e-2)" "unprognostic (3.46e-2)" "unprognostic (7.29e-2)" "unprognostic (3.63e-2)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" 6.7 7.3 8.7 5.1 14.0 8.0 6.0 17.8 22.0 7.0 7.2 10.9 3.8 3.3 8.5 6.2 4.2 7.8 6.2 10.7 9.4 11.5 6.1 4.3 6.1 5.5 11.1 14.8 11.5 3.3 9.0 13.9 8.8 24.7 8.2 5.6 7.6 4.8 6.5 11.6 6.3 4.6 8.4 10.9 7.1 4.9 41.8 10.8 3.6 6.7 1.9 5.4 6.8 8.7 2.5 1.4 1.3 3.0 2.1 3.1 0.7 6.1 3.4 9.2 4.9 6.3 6.6 1.9 5.1 7.2 4.4 6.6 4.6 1.4 4.0 6.4 4.8 4.1 8.1 6.0 6.7 12.9 5.7 4.9 7.6 1.9 4.9 7.0 8.6 5.2 6.2 3.9 20.8 5.5 7.4 6.5 4.1 0.8 4.7 5.0 2.6 3.8 7.9 8.7 1.9 5.5 3.8 6.9 7.8 12.4 0.9 2.6 3.2 8.7 6.7 5.7 5.7 7.0 7.0 7.5 10.0 5.9 4.2 5.5 3.6 0.4 3.0 1.2 1.7 1.4 3.1 1.5 1.6 1.3 0.8 2.5 2.1 1.5 1.3 2.1 1.5 1.4 0.5 0.7 8.7 14.0 17.8 22.0 9.4 11.5 11.1 14.8 24.7 10.8 TTC3 "DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII" ENSG00000182670 "Tetratricopeptide repeat domain 3" P53804 21 37073226-37203112 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016810, HPA023964, HPA036304" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Nucleoli" Cytosol "HPA016810: AB_1858434, HPA023964: AB_1858435, HPA036304: " "unprognostic (3.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (8.52e-2)" "unprognostic (9.29e-2)" "unprognostic (8.71e-2)" "unprognostic (1.61e-1)" "unprognostic (2.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (6.74e-2)" 22.9 22.1 34.0 18.7 36.5 12.0 23.4 39.2 40.0 34.9 20.6 15.9 26.7 13.0 21.6 33.3 15.3 19.5 19.0 21.5 29.1 16.5 21.4 17.0 15.4 14.3 17.7 27.5 34.5 25.8 27.4 50.4 15.2 34.7 28.9 19.9 16.1 24.5 25.4 21.6 16.1 16.8 21.6 21.7 13.6 21.3 19.5 19.9 19.7 35.4 11.1 15.1 23.3 18.9 10.6 12.8 4.8 5.7 9.1 18.6 3.8 21.4 7.6 35.7 6.7 34.5 50.2 12.4 23.6 29.4 10.7 14.5 10.1 10.8 18.5 8.2 39.5 7.0 10.7 14.5 15.1 19.6 7.7 37.4 11.5 13.1 12.6 20.8 12.1 25.9 9.0 10.8 9.7 15.8 22.5 21.8 20.0 16.6 20.2 5.4 10.1 13.0 27.1 17.1 9.7 12.4 16.6 27.3 20.8 29.3 16.8 15.2 19.0 8.2 20.5 15.3 6.1 18.7 8.8 21.9 15.7 18.5 25.2 20.9 11.5 2.9 4.4 4.8 9.1 4.8 13.6 9.5 10.6 12.3 7.9 10.6 18.6 11.3 0.7 9.1 5.7 12.8 7.2 3.8 34.0 36.5 39.2 40.0 29.1 16.5 17.7 27.5 34.7 19.9 TTK "CT96, MPH1, MPS1, MPS1L1" ENSG00000112742 "TTK protein kinase" P33981 6 80003887-80042527 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.3;testis: 31.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 4.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010166, CAB013229" Enhanced Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "CAB010166: AB_632567, CAB013229: AB_2533230" "unprognostic (4.27e-2)" "unprognostic (8.71e-2)" "unprognostic (1.04e-2)" "prognostic unfavourable (1.44e-5)" "unprognostic (7.97e-2)" "unprognostic (4.78e-2)" "prognostic unfavourable (3.84e-10)" "unprognostic (1.56e-3)" "unprognostic (7.95e-2)" "unprognostic (2.02e-3)" "prognostic unfavourable (2.54e-4)" "unprognostic (1.54e-1)" "unprognostic (0.00e+0)" "unprognostic (3.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" 1.1 1.4 0.3 3.2 0.4 13.9 1.0 0.3 0.4 1.0 2.7 0.2 0.2 2.2 0.5 1.0 6.5 0.3 0.4 1.5 0.4 0.3 0.9 0.6 1.2 4.6 0.4 0.2 0.4 0.5 0.0 0.3 3.0 0.6 0.6 3.6 0.3 1.2 0.6 0.3 2.0 2.8 0.7 0.8 2.1 1.8 31.7 0.2 58.3 0.5 2.6 5.4 0.8 1.8 1.7 0.0 1.1 0.0 1.1 4.0 0.8 13.3 8.0 24.0 19.7 1.1 3.5 13.6 15.5 9.6 22.7 27.8 10.9 10.2 19.8 12.1 6.6 17.4 21.2 9.5 31.7 18.0 17.1 18.3 10.7 8.9 0.0 21.5 12.0 0.4 1.0 15.9 10.2 12.8 20.0 20.5 19.3 9.9 12.3 15.6 14.2 9.7 11.0 43.9 8.2 5.7 8.6 16.6 9.7 9.1 9.9 5.6 9.3 16.4 5.3 10.2 10.2 6.6 24.8 4.6 15.5 11.0 3.6 20.1 8.7 0.0 0.0 1.1 0.6 0.0 0.6 0.9 1.0 1.6 0.0 1.7 0.3 0.5 0.3 1.1 0.0 0.0 4.0 0.8 0.3 0.4 0.3 0.4 0.4 0.3 0.4 0.2 0.6 0.2 TTL MGC46235 ENSG00000114999 "Tubulin tyrosine ligase" Q8NG68 2 112482154-112541739 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066819 Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA066819: " "unprognostic (1.05e-2)" "unprognostic (3.90e-3)" "unprognostic (2.25e-1)" "unprognostic (3.95e-3)" "unprognostic (9.75e-2)" "unprognostic (1.81e-2)" "prognostic unfavourable (5.65e-4)" "unprognostic (2.95e-1)" "unprognostic (3.65e-1)" "unprognostic (2.10e-1)" "unprognostic (5.48e-2)" "unprognostic (7.19e-2)" "unprognostic (6.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" 4.4 4.0 9.9 4.2 11.9 7.1 11.3 5.0 12.5 3.3 4.1 9.2 2.5 3.1 4.6 4.2 5.2 3.2 4.9 10.3 9.4 6.5 3.9 3.3 5.9 4.4 8.1 5.3 3.2 3.8 4.1 2.4 5.3 5.9 3.2 3.9 2.6 3.0 3.7 13.1 6.0 3.2 5.8 5.4 4.0 3.2 3.0 6.5 5.1 4.2 5.2 3.8 4.8 2.9 1.8 1.2 2.7 1.3 1.0 1.3 0.5 3.7 2.8 3.6 8.1 4.4 6.2 1.4 6.4 5.3 6.8 5.9 3.5 1.3 3.5 3.6 5.5 2.6 6.3 3.3 8.3 2.4 3.6 2.9 4.0 4.4 1.9 4.1 1.5 2.8 2.3 9.9 5.3 5.8 4.8 2.8 5.3 1.9 3.5 2.3 3.1 5.8 3.8 4.1 1.9 2.1 2.9 7.7 5.4 5.0 1.7 8.9 1.7 2.4 5.7 8.1 5.9 6.3 4.7 1.5 3.1 2.9 9.0 3.1 3.4 2.7 1.3 1.0 1.3 0.8 1.1 0.8 1.0 1.0 0.4 1.8 0.9 1.1 2.4 1.0 1.1 1.2 0.8 0.5 9.9 11.9 5.0 12.5 9.4 6.5 8.1 5.3 5.9 6.5 TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 136.5;skeletal muscle: 713.8;tongue: 227.0" "Cell line enhanced" "Detected in many" "RH-30: 4.8" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced 25000000 "CAB022682: , HPA007042: AB_1080292, HPA030048: " "unprognostic (1.00e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (7.11e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-1)" "unprognostic (2.65e-1)" "unprognostic (3.49e-4)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" 23.7 0.3 0.2 0.3 0.3 0.9 0.3 0.2 0.4 0.2 0.2 0.0 0.0 0.2 0.2 21.3 8.3 0.2 0.3 136.5 0.2 0.2 0.2 0.2 0.4 0.4 0.2 0.0 0.3 0.4 0.2 0.3 0.3 0.0 0.7 0.2 0.0 11.6 0.2 713.8 0.3 0.2 0.2 0.3 0.3 0.2 0.4 0.0 0.0 5.6 227.0 15.8 0.3 0.2 7.0 0.3 1.9 0.3 5.0 7.3 0.1 0.7 0.3 1.9 1.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 1.8 0.3 2.4 0.6 0.0 1.7 0.0 0.0 0.0 2.3 2.0 3.7 2.6 1.0 0.0 0.3 0.8 2.4 0.0 0.0 0.0 1.4 2.1 1.2 0.4 0.4 1.6 2.5 0.4 1.8 1.3 4.8 1.3 0.0 0.6 1.0 1.7 0.4 1.3 0.0 0.7 2.4 1.6 0.0 0.0 0.9 0.4 3.5 0.4 3.5 0.1 1.1 0.9 1.9 0.3 0.7 0.5 0.2 0.2 6.9 1.2 0.9 0.2 7.0 2.7 3.5 1.3 5.0 0.2 0.3 7.3 0.1 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 TUT1 "FLJ21850, FLJ22267, FLJ22347, PAPD2, RBM21, TUTase" ENSG00000149016 "Terminal uridylyl transferase 1, U6 snRNA-specific" Q9H6E5 11 62575045-62592177 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA069055, HPA071838" Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA069055: , HPA071838: " "unprognostic (3.81e-2)" "unprognostic (3.54e-2)" "prognostic unfavourable (9.51e-4)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.59e-2)" "unprognostic (1.83e-1)" "unprognostic (2.59e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (2.71e-1)" "unprognostic (7.20e-3)" "unprognostic (1.03e-2)" "unprognostic (4.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.97e-3)" 10.9 12.1 10.7 9.9 13.6 7.8 12.9 13.5 13.3 10.5 8.7 15.9 13.0 12.9 11.5 10.8 10.0 16.9 13.7 10.7 13.6 8.3 12.2 22.7 9.6 18.1 15.5 9.5 14.5 26.2 15.5 16.2 12.3 13.0 13.9 6.2 11.9 16.4 11.9 20.5 13.9 11.7 10.2 11.4 14.6 12.5 18.6 13.2 17.1 14.0 8.8 13.6 11.5 9.8 13.1 9.4 6.6 7.3 9.8 16.0 7.2 7.2 9.1 6.3 8.8 7.7 4.4 8.2 7.8 4.8 6.6 5.8 8.2 14.2 11.6 18.1 3.8 13.7 11.6 9.1 3.4 8.9 6.1 11.9 9.3 7.7 8.6 8.4 5.4 6.2 9.8 8.3 12.6 6.3 17.8 12.0 5.6 15.9 11.9 17.9 7.2 11.2 13.4 10.1 28.1 6.1 4.2 10.5 14.7 6.0 11.3 9.7 15.8 8.2 5.7 7.5 6.8 8.7 5.9 20.9 18.3 14.2 8.8 6.7 6.2 5.9 5.9 6.6 10.5 7.3 14.6 9.8 9.9 8.4 7.8 13.1 16.0 12.5 3.6 9.8 5.3 9.4 8.9 7.2 10.7 13.6 13.5 13.3 13.6 8.3 15.5 9.5 13.0 13.2 TWNK "C10orf2, FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL" ENSG00000107815 "Twinkle mtDNA helicase" Q96RR1 10 100987367-100994401 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "Helicase, Hydrolase" "Deafness, Disease mutation, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002532 Uncertain "HPA002532: AB_1078311" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "unprognostic (1.16e-1)" "unprognostic (2.19e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (7.82e-3)" "unprognostic (7.99e-2)" "unprognostic (1.22e-1)" "unprognostic (7.95e-2)" "unprognostic (7.52e-2)" "unprognostic (1.96e-2)" "unprognostic (9.46e-2)" "unprognostic (9.82e-3)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" 8.5 12.1 8.4 11.1 9.9 4.2 12.6 8.7 10.4 6.1 7.3 6.0 2.6 5.4 9.1 9.0 10.1 11.4 6.6 8.4 8.7 5.1 8.4 10.8 4.4 9.6 10.6 7.4 9.8 14.7 9.5 11.1 6.4 9.4 7.7 8.3 3.9 6.8 5.9 32.5 9.6 6.8 7.4 12.2 10.4 7.0 15.0 10.9 12.6 8.9 9.8 13.1 6.6 14.1 5.4 2.4 1.1 1.5 4.7 7.8 2.5 6.4 13.6 5.4 17.2 5.0 3.4 6.5 4.7 6.4 7.7 7.6 22.4 5.7 23.3 9.3 2.9 10.8 22.7 11.8 9.7 10.8 13.4 17.6 8.0 17.2 8.4 22.5 7.3 6.7 13.6 11.2 35.2 4.7 18.9 6.5 5.3 8.8 15.3 8.2 15.6 11.4 14.9 12.0 14.2 5.0 6.6 8.8 17.0 5.1 7.0 17.0 9.1 7.7 5.3 3.8 7.8 4.7 13.9 12.2 12.6 19.9 4.6 20.7 4.2 1.1 1.1 0.1 2.6 0.9 7.8 5.4 3.8 5.0 2.1 4.0 4.1 4.5 0.0 4.7 1.5 2.4 1.0 2.5 8.4 9.9 8.7 10.4 8.7 5.1 10.6 7.4 9.4 10.9 TXK "BTKL, PSCTK5, PTK4, RLK, TKL" ENSG00000074966 "TXK tyrosine kinase" P42681 4 48066393-48134256 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 43.5;lymphoid tissue: 49.1;placenta: 28.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.7;HMC-1: 11.0;U-266/70: 5.4;U-266/84: 6.7;WM-115: 24.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "NK-cell: 43.5" "Group enriched" "Detected in many" 26 "NK-cells: 43.5;T-cells: 17.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062482 Approved Vesicles Vesicles "HPA062482: " "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (9.24e-3)" "unprognostic (1.09e-2)" "unprognostic (2.58e-4)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (1.50e-1)" "unprognostic (6.39e-3)" "unprognostic (8.13e-2)" "unprognostic (4.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (2.59e-1)" "unprognostic (2.04e-2)" 1.8 1.5 0.3 15.3 0.4 3.9 1.5 0.2 0.6 0.8 2.1 0.3 0.2 1.3 1.3 11.6 2.4 2.6 1.7 0.7 0.2 0.4 2.1 2.8 4.0 49.1 0.5 0.5 0.5 1.0 0.4 1.3 28.4 0.6 0.9 1.0 1.0 6.1 0.2 0.5 1.7 7.9 0.4 0.4 17.8 1.0 1.7 0.2 14.0 1.9 0.2 19.3 2.4 1.4 0.0 0.1 1.1 0.0 43.5 17.5 10.6 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 4.7 0.0 1.4 0.0 0.2 0.0 0.0 0.4 0.2 0.1 2.3 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.6 0.0 0.0 2.0 0.0 0.8 0.3 0.0 0.0 1.3 1.2 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.4 0.0 0.0 0.3 0.1 5.4 6.7 0.4 0.0 0.4 24.8 1.1 0.0 0.3 13.2 0.0 17.4 0.0 6.8 6.4 0.0 0.0 17.5 11.9 0.8 43.5 0.0 0.1 5.1 10.6 0.3 0.4 0.2 0.6 0.2 0.4 0.5 0.5 0.6 0.2 TXNRD1 "GRIM-12, Trxr1, TXNR" ENSG00000198431 "Thioredoxin reductase 1" Q16881 12 104215779-104350305 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 143.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001395, CAB004607, CAB015834, HPA043871" Approved Supported Nucleoplasm 5900000 Nucleoplasm "CAB004607: AB_628405, CAB015834: , HPA001395: AB_1858377, HPA043871: " "unprognostic (2.52e-2)" "unprognostic (1.16e-1)" "unprognostic (5.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (1.94e-2)" "prognostic unfavourable (1.12e-5)" "unprognostic (5.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavourable (1.20e-5)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.18e-2)" "unprognostic (8.80e-2)" 19.1 79.2 14.1 15.6 16.9 22.6 18.5 11.1 13.7 13.0 21.8 9.7 19.7 23.5 23.5 14.7 16.7 19.0 23.2 32.4 11.0 11.7 25.3 19.6 29.3 18.1 12.0 10.9 16.4 7.9 10.5 16.2 30.8 16.4 25.3 19.1 18.1 10.6 26.5 30.0 5.7 17.0 99.6 10.9 14.9 24.2 14.8 8.9 15.6 16.5 16.9 13.2 73.2 72.0 8.1 14.2 37.6 16.2 8.3 10.2 8.7 22.0 102.6 11.9 11.2 57.5 32.2 41.6 41.0 26.0 18.5 19.2 10.8 32.9 16.5 19.1 143.4 7.7 23.5 15.7 22.0 8.0 10.2 13.9 80.6 45.6 92.3 21.7 15.2 18.3 16.2 40.9 13.1 63.4 19.1 7.8 27.7 10.6 22.2 9.9 11.5 105.8 22.0 8.3 14.3 21.5 12.1 18.6 11.2 33.1 52.4 32.7 12.4 12.8 84.7 9.1 18.9 20.3 33.5 8.6 16.8 24.8 19.1 12.0 53.9 33.0 10.6 24.7 9.1 14.0 10.2 8.1 8.4 9.0 14.2 5.2 7.6 6.6 37.6 8.3 16.2 9.2 7.1 8.7 14.1 16.9 11.1 11.2 11.0 11.7 12.0 10.9 16.4 8.9 TXNRD2 "TR, TR3, TRXR2" ENSG00000184470 "Thioredoxin reductase 2" Q9NNW7 22 19875517-19941992 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2 OS: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002007, HPA003323" Supported Supported Mitochondria,Cytosol 410000 Mitochondria Cytosol "CAB002007: , HPA003323: AB_1080396" "unprognostic (3.17e-2)" "unprognostic (8.72e-2)" "unprognostic (4.30e-1)" "unprognostic (9.71e-3)" "unprognostic (7.25e-2)" "unprognostic (6.35e-2)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (2.83e-1)" "unprognostic (4.94e-3)" "unprognostic (2.49e-1)" "prognostic favourable (1.10e-7)" "unprognostic (2.47e-1)" "unprognostic (5.99e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" 9.8 30.2 8.5 8.3 10.1 11.6 7.4 19.0 15.0 8.3 10.3 9.0 7.6 9.2 11.9 12.3 8.8 8.4 13.0 22.6 8.3 7.5 13.9 40.9 10.8 8.4 7.8 9.7 11.9 13.0 9.9 9.9 14.0 7.1 17.9 4.5 10.0 15.2 8.8 16.5 6.0 10.2 5.4 5.6 11.2 14.6 10.5 6.8 4.9 12.6 9.2 10.5 7.5 7.9 4.8 9.1 5.8 12.1 4.8 4.9 4.9 6.3 13.2 1.2 5.1 2.4 3.4 3.0 6.1 7.2 11.1 8.2 12.2 6.6 3.5 14.9 6.4 11.3 6.1 8.4 4.2 6.7 15.1 5.9 10.5 7.2 4.6 6.6 2.9 3.3 6.4 5.7 4.8 31.4 32.8 6.0 8.6 15.4 2.2 9.9 6.1 9.4 3.4 29.3 3.2 6.7 6.9 6.5 5.7 10.5 13.8 7.0 11.2 9.0 17.4 8.1 48.8 6.7 12.8 6.0 4.4 2.2 7.8 5.1 10.2 3.2 12.1 5.8 4.3 9.2 3.3 4.8 3.8 3.9 9.1 3.6 4.9 4.0 1.3 4.8 8.7 3.4 2.4 4.9 8.5 10.1 19.0 15.0 8.3 7.5 7.8 9.7 7.1 6.8 TXNRD3 "TGR, TR2, TRXR3" ENSG00000197763 "Thioredoxin reductase 3" Q86VQ6 3 126607052-126655155 "Enzymes, Predicted intracellular proteins" "Differentiation, Electron transport, Spermatogenesis, Transport" "Developmental protein, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 4.0" "Lineage enriched" "Detected in single" 4 "T-cells: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020802, HPA036109" Uncertain Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB020802: , HPA036109: " "unprognostic (1.41e-1)" "unprognostic (1.55e-2)" "unprognostic (3.92e-1)" "prognostic unfavourable (3.35e-4)" "unprognostic (3.90e-1)" "unprognostic (2.96e-1)" "unprognostic (3.01e-1)" "unprognostic (3.39e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "prognostic unfavourable (2.86e-4)" "unprognostic (3.14e-1)" "prognostic favourable (2.72e-4)" "unprognostic (5.94e-2)" "unprognostic (1.74e-1)" "unprognostic (1.03e-2)" "unprognostic (2.51e-1)" 5.4 5.9 4.9 2.4 4.7 0.9 7.2 5.5 5.7 7.3 4.2 4.6 5.5 1.6 8.3 7.1 6.4 4.7 5.2 4.9 4.0 2.9 6.7 10.0 7.0 5.2 4.6 3.5 8.8 7.1 12.3 8.5 3.3 7.0 5.2 3.6 6.4 5.7 5.1 7.3 4.8 2.6 8.1 5.1 3.3 4.9 27.8 5.8 5.0 7.4 3.6 2.1 6.6 5.3 0.3 0.7 0.5 0.9 0.9 4.0 0.3 13.7 3.5 4.5 7.1 8.4 12.7 2.3 6.1 5.5 5.0 7.1 6.3 7.8 0.0 7.8 8.4 5.5 5.6 6.3 6.3 0.0 4.1 1.6 3.3 4.8 7.2 5.5 0.5 11.6 5.5 1.7 11.6 3.6 3.3 0.0 8.0 9.9 1.1 3.0 6.4 2.7 0.4 3.9 2.2 5.3 6.9 7.8 4.8 17.4 5.1 8.8 7.0 2.1 6.0 6.1 1.5 8.3 2.8 3.6 1.5 0.0 3.3 1.9 5.2 0.0 0.9 0.5 0.5 0.8 0.1 0.0 0.2 0.6 0.7 0.3 4.0 1.3 0.0 0.9 0.2 0.0 0.0 0.3 4.9 4.7 5.5 5.7 4.0 2.9 4.6 3.5 7.0 5.8 TYK2 JTK1 ENSG00000105397 "Tyrosine kinase 2" P29597 19 10350529-10380676 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005157 Uncertain Approved Cytosol Cytosol "HPA005157: AB_1858480" "unprognostic (1.60e-2)" "unprognostic (6.12e-3)" "unprognostic (3.67e-2)" "prognostic favourable (9.62e-4)" "unprognostic (7.61e-2)" "prognostic favourable (1.05e-5)" "unprognostic (1.20e-2)" "unprognostic (6.16e-3)" "unprognostic (4.93e-2)" "unprognostic (1.90e-2)" "prognostic favourable (1.02e-4)" "unprognostic (1.24e-2)" "prognostic unfavourable (4.43e-4)" "unprognostic (2.10e-3)" "unprognostic (1.78e-1)" "unprognostic (4.19e-1)" "prognostic favourable (4.16e-4)" 16.8 19.0 22.9 36.0 22.6 49.4 17.5 24.4 23.9 17.8 19.4 26.7 13.9 20.0 19.3 20.2 15.0 16.8 21.8 17.0 18.3 14.0 24.0 34.4 27.5 31.5 24.7 17.4 20.0 21.3 19.0 24.8 13.9 19.1 21.1 18.6 21.6 24.4 15.4 15.6 24.4 23.8 16.7 17.9 47.9 18.5 6.4 22.8 33.9 20.9 13.5 34.7 16.7 15.1 5.8 15.8 22.9 13.4 5.3 9.1 7.3 8.5 12.5 7.5 11.7 10.0 14.1 7.2 11.7 12.0 14.9 16.4 9.6 5.7 13.0 13.8 13.1 8.6 9.0 13.8 7.9 22.9 14.0 24.0 24.9 23.5 15.6 10.1 27.7 13.6 9.8 16.9 10.0 14.4 10.1 36.4 13.1 26.9 14.8 62.3 2.4 21.9 14.8 6.4 13.3 12.1 27.6 7.0 8.7 11.5 12.1 8.4 6.7 17.2 12.2 20.1 7.2 23.1 13.7 30.0 23.3 11.9 10.0 21.1 11.2 6.6 13.4 17.0 9.1 10.2 5.9 5.6 5.5 8.1 15.8 5.8 3.8 5.1 22.9 5.3 9.7 9.0 6.8 7.3 22.9 22.6 24.4 23.9 18.3 14.0 24.7 17.4 19.1 22.8 TYMP "ECGF1, MNGIE" ENSG00000025708 "Thymidine phosphorylase" P19971 22 50525752-50530056 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Glycosyltransferase, Growth factor, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 15.9;HHSteC: 39.3;Karpas-707: 38.0;U-266/70: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "classical monocyte: 23.0;eosinophil: 18.2;intermediate monocyte: 22.4;myeloid DC: 12.2;neutrophil: 6.7;non-classical monocyte: 15.9" "Group enriched" "Detected in many" 18 "dendritic cells: 12.2;granulocytes: 18.2;monocytes: 23.0" "Low region specificity" "Detected in some" "HPA000530, HPA001072, CAB002518" Enhanced Approved "Nuclear bodies,Golgi apparatus" 16000000 "Nuclear bodies" "Golgi apparatus" "CAB002518: AB_563953, HPA000530: , HPA001072: AB_1080274" "unprognostic (7.02e-3)" "unprognostic (1.00e-1)" "unprognostic (3.61e-1)" "prognostic favourable (4.34e-5)" "unprognostic (7.60e-2)" "unprognostic (1.16e-2)" "unprognostic (2.40e-1)" "unprognostic (7.17e-2)" "unprognostic (4.64e-2)" "unprognostic (1.33e-1)" "unprognostic (3.31e-2)" "unprognostic (2.17e-1)" "prognostic unfavourable (3.50e-8)" "unprognostic (1.32e-1)" "unprognostic (4.02e-2)" "unprognostic (1.52e-2)" "unprognostic (4.60e-2)" 25.2 7.9 2.8 41.6 8.4 12.1 19.0 1.5 4.4 10.7 10.7 3.8 2.3 10.4 4.4 15.7 22.0 13.7 9.6 15.0 7.0 2.6 18.6 38.1 28.8 57.8 6.5 0.4 7.5 5.8 1.7 3.9 11.5 9.1 7.9 4.9 5.4 16.5 3.8 10.0 8.8 13.9 7.3 15.2 43.9 12.4 3.0 5.0 13.3 12.5 25.5 28.8 12.4 9.4 0.9 12.2 18.2 23.0 0.8 0.9 2.6 6.5 0.7 0.0 0.1 0.9 1.2 0.6 1.1 0.1 2.4 5.3 0.0 15.9 0.5 0.8 2.7 5.8 0.2 0.2 0.0 2.8 1.4 0.3 1.1 0.4 39.3 0.1 7.6 2.4 2.4 3.2 0.0 0.0 0.2 38.0 0.2 0.1 0.0 1.0 0.0 2.1 0.2 0.0 7.6 0.0 0.0 0.0 1.4 6.1 8.3 0.5 0.6 4.8 1.5 0.0 0.6 0.1 0.2 18.2 3.7 0.4 0.2 0.1 0.2 2.5 23.0 18.2 0.3 22.4 0.2 0.8 0.3 0.2 12.2 0.9 0.2 0.1 6.7 0.8 15.9 1.1 0.9 2.6 2.8 8.4 1.5 4.4 7.0 2.6 6.5 0.4 9.1 5.0 TYMS "HsT422, TMS, TS, Tsase" ENSG00000176890 "Thymidylate synthetase" P04818 18 657604-673578 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 75.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 13.8" "Group enriched" "Detected in many" 6 "NK-cells: 6.8;T-cells: 13.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "cerebellum: 6.7;olfactory region: 8.8" CAB002784 Enhanced "CAB002784: " "unprognostic (7.58e-2)" "unprognostic (2.06e-3)" "unprognostic (9.31e-2)" "unprognostic (2.34e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" "prognostic unfavourable (5.10e-6)" "unprognostic (1.62e-3)" "unprognostic (1.68e-2)" "unprognostic (9.82e-2)" "unprognostic (1.07e-3)" "unprognostic (3.28e-2)" "unprognostic (1.23e-2)" "unprognostic (6.34e-2)" "unprognostic (1.66e-1)" "unprognostic (5.65e-3)" "unprognostic (2.47e-1)" 3.0 2.6 4.6 15.5 5.8 34.9 2.8 1.2 6.3 3.4 10.1 10.2 1.5 4.8 2.5 3.6 12.3 2.4 4.6 2.0 5.8 2.9 4.8 5.1 4.2 15.4 3.4 4.5 2.0 3.1 1.1 1.3 14.3 3.4 3.0 12.9 1.1 3.4 0.8 0.7 3.6 6.9 5.5 4.6 8.9 4.2 21.5 5.3 75.5 1.7 10.9 19.3 4.8 4.3 1.2 1.8 1.0 0.1 6.8 13.8 2.5 13.7 21.2 44.3 21.4 4.9 8.2 22.5 32.5 19.4 35.1 42.1 17.9 11.0 21.4 12.7 17.5 6.2 30.9 12.2 30.4 20.1 34.3 36.3 19.9 30.7 1.1 74.5 39.8 7.3 2.9 22.1 6.9 29.3 29.1 34.4 44.1 15.8 89.7 41.3 15.9 15.9 59.4 39.9 25.8 13.2 12.2 15.1 24.5 27.4 12.7 8.2 8.7 34.0 11.6 40.6 80.2 37.1 63.3 42.7 52.5 48.9 10.7 32.3 46.4 0.0 0.0 1.0 1.1 0.1 0.0 1.2 2.9 2.2 1.8 0.0 0.0 0.7 0.6 6.8 0.1 0.3 13.8 2.5 4.6 5.8 1.2 6.3 5.8 2.9 3.4 4.5 3.4 5.3 TYR "OCA1, OCA1A, OCAIA" ENSG00000077498 Tyrosinase P14679 11 89177452-89295759 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase, Tumor antigen" "Albinism, Deafness, Disease mutation, FDA approved drug targets, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 70 "retina: 82.0;skin 1: 25.2" "Cell line enriched" "Detected in single" 844 "SK-MEL-30: 84.3" "Cancer enriched" "Detected in single" 1755 "melanoma: 351.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000079, HPA043241, HPA050889, HPA064583" Enhanced Enhanced Vesicles Vesicles "CAB000079: AB_564045, HPA043241: , HPA050889: , HPA064583: " "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-3)" "unprognostic (9.75e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 82.0 0.7 0.0 0.0 25.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 84.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583586 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.2;ovary: 48.2" "Cell line enhanced" "Detected in many" "BEWO: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 5.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved 6400000 "HPA071245: " "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" 18.3 4.1 18.7 2.1 16.6 1.5 7.7 27.3 39.2 2.3 1.8 25.6 1.2 2.3 5.0 4.2 12.7 11.7 3.1 2.5 15.1 7.8 6.4 1.6 3.2 1.9 19.6 18.2 48.2 9.5 1.3 0.8 5.9 14.0 3.3 1.7 1.7 2.4 6.7 1.4 13.0 2.9 4.8 23.1 5.4 3.6 17.9 16.6 0.0 1.8 2.2 4.1 2.9 2.8 1.2 1.0 5.0 0.9 1.0 0.8 0.2 4.7 3.1 9.9 10.8 9.3 6.4 33.5 6.9 4.4 6.9 6.4 17.6 1.6 0.1 8.9 5.6 11.2 11.1 1.7 3.2 2.7 7.4 1.4 10.0 8.3 6.6 2.4 0.2 2.0 3.5 5.2 1.8 5.1 8.7 2.0 3.7 4.5 1.1 0.4 22.9 3.2 14.7 9.0 1.7 0.6 9.2 11.9 3.4 6.5 10.3 7.7 8.5 2.8 3.9 13.7 6.0 10.1 10.4 0.8 1.6 1.4 8.3 15.8 8.2 2.6 0.9 0.8 0.6 0.5 0.6 0.7 0.6 0.8 0.3 1.2 0.7 0.7 5.0 1.0 0.5 1.0 0.5 0.2 18.7 16.6 27.3 32.7 15.1 7.8 19.6 18.2 14.0 16.6 TYSND1 "MGC34695, NET41" ENSG00000156521 "Trypsin domain containing 1" Q2T9J0 10 70137981-70146676 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 40.7" "Cell line enhanced" "Detected in many" "HaCaT: 17.7;PC-3: 27.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030304 Approved Uncertain Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Centrosome" Cytosol "HPA030304: AB_10670560" "unprognostic (4.75e-3)" "unprognostic (4.30e-2)" "unprognostic (2.44e-2)" "unprognostic (7.69e-2)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.02e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (1.59e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-1)" "unprognostic (9.26e-3)" "unprognostic (1.91e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" 15.2 8.2 4.7 7.0 6.8 3.0 8.0 6.7 7.3 6.0 6.7 5.9 6.9 10.1 5.3 8.4 13.9 5.4 5.2 3.5 3.7 2.8 7.4 7.4 3.5 7.2 3.7 3.6 5.6 9.0 3.3 4.5 4.7 3.5 6.9 2.7 6.9 8.0 5.7 5.3 12.5 8.5 4.8 4.7 9.0 8.2 40.7 3.4 6.2 8.5 6.6 10.1 6.5 7.6 6.1 1.4 1.2 1.6 2.9 6.3 2.3 9.4 6.7 0.5 4.0 0.7 0.6 2.4 1.2 0.8 1.4 1.3 4.3 6.0 8.4 4.0 0.3 17.7 0.7 2.6 0.3 5.3 6.0 0.5 1.9 2.1 1.6 0.7 0.0 1.2 5.1 1.2 2.1 1.0 0.0 2.6 0.6 4.2 3.2 3.5 2.2 27.2 5.6 1.6 3.7 0.6 1.6 4.9 2.5 4.1 9.3 3.6 6.0 0.7 1.7 1.6 1.1 3.0 5.3 9.6 5.8 4.1 1.9 3.6 1.2 0.0 1.3 1.2 6.3 1.6 4.1 5.1 3.7 4.9 1.4 6.1 5.3 4.4 0.4 2.9 1.1 1.0 4.0 2.3 4.7 6.8 6.7 7.3 3.7 2.8 3.7 3.6 3.5 3.4 TYW1 "FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W" ENSG00000198874 "TRNA-yW synthesizing protein 1 homolog" Q9NV66 7 66995173-67239519 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA013568, HPA014118, HPA015535, HPA043136, HPA047029, HPA047052, HPA052097" Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA013568: , HPA014118: , HPA015535: AB_1856487, HPA043136: , HPA047029: , HPA047052: , HPA052097: " "unprognostic (1.53e-1)" "unprognostic (5.49e-3)" "unprognostic (1.62e-1)" "unprognostic (3.05e-2)" "unprognostic (1.84e-2)" "unprognostic (2.20e-1)" "unprognostic (1.83e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "prognostic unfavourable (1.73e-4)" "unprognostic (4.86e-2)" "unprognostic (1.30e-1)" "unprognostic (1.85e-2)" "unprognostic (4.70e-2)" "unprognostic (1.60e-1)" "unprognostic (1.36e-2)" "unprognostic (1.79e-2)" 15.4 19.1 10.2 12.3 15.4 11.9 15.1 14.9 15.3 18.8 12.9 21.2 18.2 14.1 22.7 15.3 12.0 15.5 10.8 12.9 10.8 9.8 15.2 17.7 11.1 15.5 14.1 10.8 19.4 23.9 22.9 28.0 13.2 14.5 14.9 16.5 17.8 15.3 14.7 26.2 14.4 12.8 14.0 13.9 15.1 12.6 13.7 13.4 19.7 19.0 13.6 23.3 15.3 15.2 9.6 8.3 3.6 9.1 11.2 11.8 5.3 10.5 13.5 8.3 17.1 12.4 8.6 9.6 11.3 8.6 9.0 8.4 15.4 13.8 18.4 17.4 10.4 12.5 17.1 13.9 13.0 14.4 13.1 7.9 11.2 10.4 12.3 18.3 10.6 8.8 14.1 12.1 18.7 8.1 20.9 11.1 10.2 10.4 11.5 15.3 14.5 12.1 13.1 11.6 23.1 12.2 10.7 12.7 12.6 13.6 26.4 11.3 18.0 13.0 9.5 10.3 7.4 8.2 15.4 11.2 15.8 22.2 8.4 17.2 14.2 2.0 7.0 3.6 8.6 7.8 11.7 8.5 9.4 9.8 8.3 9.6 11.5 11.8 2.0 11.2 9.1 6.6 6.8 5.3 10.2 15.4 14.9 15.3 10.8 9.8 14.1 10.8 14.5 13.4 TYW3 "C1orf171, FLJ40918" ENSG00000162623 "TRNA-yW synthesizing protein 3 homolog" Q6IPR3 1 74733152-74766678 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029641 Approved Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA029641: AB_2272535" "unprognostic (6.89e-3)" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" "unprognostic (7.24e-2)" "prognostic unfavourable (1.49e-7)" "unprognostic (3.79e-1)" "unprognostic (2.23e-1)" "unprognostic (2.96e-1)" "unprognostic (4.08e-2)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (2.05e-1)" "unprognostic (8.90e-2)" "unprognostic (2.98e-3)" 16.5 19.7 13.7 13.5 17.7 11.9 18.3 15.0 19.9 20.4 17.7 7.5 13.7 9.5 21.0 15.2 20.6 16.4 10.0 21.1 11.1 12.9 20.4 17.0 11.3 14.3 16.2 17.2 30.0 14.4 22.2 34.3 13.5 17.0 20.7 12.3 8.6 13.8 15.7 12.3 10.5 10.9 24.7 15.6 16.0 14.8 12.3 18.1 12.3 23.5 14.3 16.9 23.5 33.3 9.7 9.0 6.0 8.0 13.6 13.9 5.2 8.4 7.1 12.4 8.8 14.1 15.4 18.8 14.6 13.4 14.0 12.3 15.1 7.2 22.3 13.4 12.6 6.9 14.1 16.9 17.6 13.8 12.2 17.5 21.8 29.2 9.2 34.9 11.3 11.7 17.1 17.8 17.3 12.4 30.3 17.1 17.9 7.2 17.0 11.7 32.8 16.7 16.1 25.8 10.0 12.0 11.1 9.6 8.2 6.9 19.1 22.4 10.4 12.8 8.0 6.2 17.0 16.8 17.5 9.9 17.9 15.6 13.9 12.7 17.8 6.0 6.0 1.6 10.3 8.0 9.9 9.7 9.1 9.3 9.0 8.8 13.2 13.9 0.5 13.6 5.9 8.7 8.4 5.2 13.7 17.7 15.0 19.9 11.1 12.9 16.2 17.2 17.0 18.1 TYW5 "C2orf60, FLJ37953" ENSG00000162971 "TRNA-yW synthesizing protein 5" A2RUC4 2 199929975-199955736 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028294, HPA045803" Uncertain Approved "Nuclear bodies" "Nuclear bodies" "HPA028294: , HPA045803: AB_10964878" "unprognostic (3.44e-3)" "unprognostic (3.74e-1)" "unprognostic (2.11e-1)" "unprognostic (3.03e-2)" "unprognostic (9.22e-3)" "unprognostic (4.95e-2)" "unprognostic (1.47e-3)" "unprognostic (9.72e-2)" "unprognostic (6.55e-3)" "unprognostic (6.30e-3)" "unprognostic (9.54e-2)" "unprognostic (6.98e-3)" "unprognostic (2.87e-3)" "unprognostic (8.67e-2)" "unprognostic (4.46e-1)" "unprognostic (2.08e-1)" "unprognostic (5.42e-3)" 4.5 7.5 5.7 7.4 9.3 6.7 4.4 7.8 8.4 4.2 5.1 4.0 5.2 5.8 4.4 6.4 6.1 5.8 3.8 5.5 7.3 5.0 5.5 8.8 3.5 5.4 7.0 3.5 5.5 6.3 6.2 7.5 5.2 5.7 4.6 4.5 4.5 4.4 4.6 4.2 6.7 6.1 4.5 7.4 5.5 4.8 4.2 6.8 4.2 5.4 2.9 5.3 5.9 4.2 2.4 1.4 2.2 2.4 0.1 3.4 0.7 2.5 4.0 3.0 1.8 2.2 1.4 6.0 5.3 2.3 3.9 3.3 4.1 3.0 1.4 3.8 2.5 2.7 7.5 2.4 4.9 4.8 3.0 3.3 5.8 4.9 5.8 4.8 3.0 3.0 5.0 2.7 4.1 3.5 4.5 3.2 2.3 3.0 3.5 4.3 4.8 7.6 2.2 3.6 2.0 4.7 3.5 3.1 1.5 3.0 5.3 6.2 3.0 4.3 3.6 2.9 2.8 3.0 3.8 2.6 4.7 2.5 2.7 3.9 3.7 2.1 1.7 2.2 1.4 1.3 1.6 2.4 1.9 2.6 1.4 1.4 2.0 3.4 1.3 0.1 2.4 0.4 2.1 0.7 5.7 9.3 7.8 8.4 7.3 5.0 7.0 3.5 5.7 6.8 UAP1 "AgX, AGX1, SPAG2" ENSG00000117143 "UDP-N-acetylglucosamine pyrophosphorylase 1" Q16222 1 162561506-162599842 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 105.7;U-251 MG: 68.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014659 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" 19000 "Nucleoplasm, Plasma membrane, Cytosol" "HPA014659: AB_1857409" "unprognostic (2.32e-2)" "unprognostic (2.45e-1)" "unprognostic (2.07e-2)" "unprognostic (1.28e-2)" "unprognostic (2.71e-2)" "unprognostic (1.46e-2)" "unprognostic (1.37e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (4.96e-2)" "prognostic unfavourable (5.12e-5)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "unprognostic (3.51e-1)" "unprognostic (3.45e-2)" 38.4 18.5 7.0 17.4 9.8 17.2 24.8 9.0 13.4 16.1 26.9 5.7 45.7 17.2 10.9 19.4 23.6 15.7 18.3 22.5 7.7 7.8 11.0 67.1 16.0 7.4 6.6 8.9 20.4 31.4 5.1 16.0 21.5 9.1 13.9 26.9 7.8 43.9 62.5 19.4 12.4 33.4 28.8 7.1 8.1 23.0 37.7 3.7 5.6 12.4 13.5 15.3 24.4 16.7 8.3 5.6 8.1 1.6 6.2 16.1 4.8 29.9 2.1 6.0 4.8 29.2 23.4 4.1 44.1 16.2 34.0 27.8 5.7 14.1 1.1 9.9 33.8 5.2 6.7 12.8 56.1 4.7 10.1 5.3 6.9 11.1 13.7 9.0 3.6 10.8 6.1 37.3 105.7 20.8 29.9 12.4 45.4 5.5 5.2 5.8 4.4 9.8 4.7 11.7 14.6 5.3 3.5 6.4 6.7 19.2 12.0 10.2 5.9 10.3 35.3 17.2 15.8 43.2 68.8 20.8 7.3 9.9 9.8 4.2 10.8 1.0 1.6 8.1 13.0 1.6 16.1 8.3 7.9 13.3 3.4 6.5 7.6 9.5 1.6 6.2 0.8 5.6 3.9 4.8 7.0 9.8 9.0 13.4 7.7 7.8 6.6 8.9 9.1 3.7 UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Enhanced Nucleoplasm 16000000 Nucleoplasm "CAB019435: AB_2211440, CAB073410: , HPA000289: AB_1080443, HPA001506: AB_2756305" "unprognostic (7.18e-3)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" "unprognostic (2.40e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" "prognostic unfavourable (6.10e-5)" "unprognostic (7.22e-2)" "unprognostic (2.42e-3)" "unprognostic (3.43e-2)" "unprognostic (8.50e-3)" "unprognostic (2.17e-3)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (5.38e-2)" "prognostic favourable (1.78e-4)" "unprognostic (1.21e-2)" 45.6 63.0 56.0 47.2 50.6 42.0 38.3 58.1 75.7 48.0 39.3 55.9 44.9 36.3 52.9 34.1 59.4 56.0 39.9 48.7 49.5 39.9 51.1 60.0 42.0 48.2 47.7 62.3 57.6 34.9 78.8 55.5 39.1 47.6 40.2 35.5 41.0 47.5 45.7 77.7 56.1 37.9 59.4 35.5 53.4 38.7 36.0 48.6 52.7 65.0 43.9 54.0 39.2 52.7 28.9 30.6 32.6 36.0 25.6 29.0 24.1 45.8 47.6 54.5 82.8 37.3 34.0 24.1 30.5 32.5 43.9 35.8 37.8 35.0 34.2 20.3 61.0 44.3 68.3 64.9 32.3 28.3 69.4 21.4 52.8 30.3 26.3 36.0 46.2 31.9 34.0 63.8 49.8 57.5 23.2 30.8 43.5 58.1 33.9 31.9 58.0 74.4 39.5 38.0 58.2 35.1 49.4 35.3 26.5 90.9 44.2 20.2 61.5 22.5 42.0 33.0 38.3 47.5 28.4 21.1 21.9 48.8 33.9 25.8 39.4 17.4 27.0 27.4 29.0 36.0 25.4 28.9 24.0 25.9 30.6 22.0 19.1 23.4 32.6 25.6 32.8 20.8 28.2 24.1 56.0 50.6 58.1 75.7 49.5 39.9 47.7 62.3 47.6 48.6 UBA6 "FLJ10808, UBE1L2" ENSG00000033178 "Ubiquitin like modifier activating enzyme 6" A0AVT1 4 67612652-67701179 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037001 Approved Enhanced Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA037001: AB_10672787" "unprognostic (2.52e-1)" "unprognostic (4.89e-2)" "unprognostic (3.97e-3)" "unprognostic (2.81e-1)" "unprognostic (3.67e-2)" "unprognostic (4.92e-2)" "unprognostic (3.55e-3)" "unprognostic (6.06e-3)" "unprognostic (1.09e-1)" "unprognostic (1.10e-2)" "unprognostic (3.38e-2)" "unprognostic (5.30e-2)" "prognostic unfavourable (7.01e-5)" "unprognostic (2.35e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.05e-3)" 16.8 12.6 14.1 14.1 16.6 22.7 13.0 18.0 16.0 17.0 10.5 14.6 7.0 12.2 16.7 10.0 20.5 9.9 12.4 9.5 12.0 12.0 10.2 16.4 14.5 17.3 18.7 11.2 14.3 10.9 17.4 44.8 18.5 17.7 12.7 13.2 7.5 13.7 10.4 10.1 12.6 15.3 13.4 20.7 16.9 13.9 14.6 18.6 27.1 12.3 13.3 19.9 15.7 19.5 5.6 5.1 9.3 4.0 9.7 5.8 1.9 14.8 8.3 13.8 10.8 6.8 8.1 9.3 30.8 12.1 14.1 16.5 8.7 20.1 18.8 11.0 12.6 8.8 14.2 15.3 21.3 21.6 4.0 12.0 14.7 8.1 5.8 21.1 9.2 5.7 4.9 18.2 11.1 12.4 28.6 11.2 16.6 5.6 21.9 4.8 8.1 10.1 13.0 28.3 6.9 11.5 16.9 6.7 8.5 17.4 12.4 5.8 8.2 5.7 17.9 13.1 14.7 10.6 13.4 8.1 6.3 19.0 23.3 5.9 12.5 9.3 3.0 4.6 4.4 3.9 4.8 5.6 5.1 5.8 3.7 5.2 3.9 4.5 2.2 9.7 4.0 5.1 4.2 1.9 14.1 16.6 18.0 16.0 12.0 12.0 18.7 11.2 17.7 18.6 UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655675-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.5;lymphoid tissue: 27.7" "Cell line enhanced" "Detected in many" "HEL: 41.7;HMC-1: 31.7;hTEC/SVTERT24-B: 25.9;REH: 24.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebellum: 32.5;pons and medulla: 21.2" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038605, HPA038607" Approved Approved "Plasma membrane" 2200000 "Plasma membrane" "HPA038605: AB_10669648, HPA038607: " "unprognostic (4.94e-2)" "unprognostic (6.03e-3)" "unprognostic (1.34e-1)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.09e-2)" "unprognostic (4.67e-3)" "unprognostic (1.21e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (6.20e-2)" "unprognostic (9.02e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (2.72e-3)" "unprognostic (1.53e-1)" 4.3 1.3 2.8 5.5 4.0 7.2 1.5 32.5 4.9 4.0 1.5 0.7 0.0 1.7 1.3 0.3 1.8 1.1 2.4 1.3 3.4 3.5 1.5 1.7 5.5 10.9 5.1 1.9 0.8 1.2 0.6 0.9 16.8 21.2 1.3 1.8 0.9 1.3 0.9 1.8 4.1 2.4 2.3 2.1 27.7 1.7 2.1 0.2 23.9 2.9 1.7 3.8 3.4 1.3 1.0 1.7 9.8 11.0 6.5 4.9 1.8 4.4 10.9 2.0 2.6 0.8 1.6 10.3 15.8 8.8 6.4 5.0 4.3 2.4 1.8 1.2 8.4 2.2 0.0 5.6 10.3 0.0 0.3 41.7 0.3 3.6 2.4 5.0 31.7 1.4 0.3 25.9 9.6 4.3 0.0 0.0 6.2 0.1 6.1 3.2 0.8 2.6 24.9 1.2 0.2 10.2 3.8 4.5 0.1 4.2 0.3 3.5 0.0 1.3 11.2 8.4 4.5 4.9 6.5 0.3 0.0 5.3 4.4 7.1 15.2 0.0 1.3 9.8 2.0 6.5 2.2 0.3 2.6 1.8 1.7 1.0 3.0 1.6 2.8 6.5 11.0 0.2 4.9 1.8 2.8 4.0 32.5 4.9 3.4 3.5 5.1 1.9 21.2 0.2 UBE2A "HHR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574467-119591083 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: , HPA051765: , HPA065898: " "unprognostic (2.27e-3)" "prognostic favourable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavourable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavourable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 24.8 20.6 26.7 23.1 24.6 16.8 32.5 20.2 24.2 23.7 32.8 23.9 20.2 21.7 23.8 26.7 37.2 20.3 21.2 42.2 23.6 22.1 32.2 26.6 22.8 26.3 26.8 19.7 18.7 17.2 24.3 18.2 112.4 24.7 20.4 30.2 20.0 21.0 22.6 46.8 23.6 29.2 27.9 29.1 25.1 20.4 17.0 19.5 36.3 23.2 32.8 31.5 26.7 24.0 21.0 29.0 34.1 36.3 12.8 21.2 17.4 32.5 27.5 17.3 14.6 30.3 37.4 16.2 33.8 30.2 40.3 38.3 14.2 22.4 25.8 34.4 37.2 23.5 24.7 17.9 38.9 35.8 14.6 11.4 22.0 12.7 27.8 28.5 19.6 25.5 25.6 38.6 16.8 27.9 14.0 23.1 45.6 34.5 43.9 26.9 28.8 31.1 22.4 18.4 24.0 32.5 21.4 13.3 13.7 45.0 20.7 24.6 18.0 24.9 27.2 25.9 11.6 51.1 38.1 22.4 36.4 25.3 27.5 36.1 20.2 16.5 22.7 34.1 18.1 35.4 14.3 21.0 15.7 15.8 29.0 18.8 10.0 14.3 30.1 12.8 36.3 23.0 21.2 17.4 26.7 24.6 20.2 24.2 23.6 22.1 26.8 19.7 24.7 19.5 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371179-134391992 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 83.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 83.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: , HPA051765: , HPA065898: " "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 17.7 27.7 20.4 17.0 16.6 25.9 22.8 16.2 28.3 13.8 18.0 7.9 11.6 14.4 19.4 17.0 25.6 13.6 18.3 59.2 20.3 16.4 17.8 19.8 21.8 18.7 13.8 18.7 16.7 26.4 7.8 16.2 27.8 17.6 15.4 15.1 10.2 16.1 18.5 106.5 15.9 16.2 21.6 15.1 16.6 14.1 21.7 12.7 13.2 18.2 34.0 16.3 19.2 22.8 9.6 8.8 83.3 14.1 9.6 14.6 10.5 36.2 9.6 20.0 19.0 17.5 18.9 32.3 27.3 14.4 17.6 21.0 28.9 24.4 19.8 33.0 17.4 14.5 15.1 20.2 19.2 31.4 16.3 10.9 26.5 31.0 20.5 12.9 22.4 16.2 27.5 15.9 13.5 15.0 19.9 36.0 15.8 21.2 20.4 34.1 8.6 9.1 20.6 22.0 27.6 15.7 28.1 27.0 21.1 21.4 10.1 47.4 21.8 35.6 29.7 20.5 14.3 27.5 29.8 30.1 41.2 27.9 23.1 24.4 20.3 34.7 11.5 31.2 9.4 12.5 8.6 9.6 12.0 9.5 7.9 9.6 14.6 12.3 83.3 9.6 14.1 8.8 14.1 10.5 20.4 16.6 16.2 28.3 20.3 16.4 13.8 18.7 17.6 12.7 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 130.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: , HPA054975: " "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavourable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavourable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 3.1 2.3 0.4 24.0 0.9 25.1 4.3 0.4 0.7 3.8 9.5 0.4 0.8 7.8 2.0 2.6 25.6 0.6 3.2 2.8 0.5 0.4 2.1 2.1 4.6 15.6 0.6 0.5 1.2 1.3 0.0 0.6 12.6 0.9 1.3 11.7 0.7 3.7 0.6 1.0 8.3 10.0 3.5 1.2 11.6 7.0 15.3 0.5 130.8 0.8 17.6 26.3 2.8 7.8 1.2 0.9 2.7 0.6 2.4 10.0 4.2 39.2 28.8 52.0 24.9 1.4 3.2 29.9 31.2 15.8 51.4 36.9 94.6 45.4 41.6 30.6 14.8 38.8 0.2 33.4 52.5 17.7 27.4 12.8 22.1 24.8 0.4 18.3 32.2 1.0 3.6 34.8 34.1 25.0 0.2 35.4 42.3 64.6 30.2 5.2 31.2 69.0 32.1 47.1 0.2 17.3 13.6 30.0 25.0 49.1 36.0 19.7 36.3 27.0 9.1 46.1 40.3 31.3 60.3 11.2 0.3 46.4 28.0 13.1 43.7 0.0 0.1 0.0 0.2 0.0 0.0 1.2 1.2 2.3 0.9 0.2 0.2 0.1 2.7 2.4 0.6 0.5 10.0 4.2 0.4 0.9 0.4 0.7 0.5 0.4 0.6 0.5 0.9 0.5 UBE2D1 "E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A" ENSG00000072401 "Ubiquitin conjugating enzyme E2 D1" P51668 10 58334975-58370753 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 74.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 41.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (4.23e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-2)" "prognostic unfavourable (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.17e-1)" "prognostic unfavourable (8.04e-6)" "unprognostic (9.71e-3)" "unprognostic (4.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.66e-2)" 8.2 10.6 8.1 10.0 7.9 17.1 7.5 7.7 9.0 6.3 7.3 5.5 4.8 4.7 8.5 5.5 8.2 5.5 6.4 25.6 7.6 7.2 5.5 5.4 7.0 13.7 8.1 6.7 5.9 4.8 5.3 7.4 6.8 7.4 6.5 7.9 3.5 6.4 5.0 74.9 4.6 5.8 8.8 8.4 11.0 5.6 3.2 8.4 5.5 6.0 25.1 7.1 9.5 10.0 3.7 7.2 41.0 13.7 2.8 3.5 7.1 10.6 5.8 10.8 13.9 22.2 17.9 7.0 7.0 12.0 8.1 11.9 11.7 9.2 0.0 11.1 10.5 9.7 20.9 10.2 11.4 11.0 12.3 2.8 2.1 6.7 14.6 8.4 6.8 20.7 11.5 8.4 15.7 16.1 5.5 4.5 10.9 3.3 9.0 9.4 13.2 9.1 7.6 9.8 5.9 12.1 6.2 8.2 11.0 13.8 23.3 11.2 8.5 5.7 12.9 3.1 10.9 10.6 7.7 11.5 8.9 9.4 9.8 17.5 3.5 2.8 13.7 6.2 2.4 9.5 2.8 3.3 2.9 3.0 7.2 3.7 3.0 2.3 41.0 2.8 7.9 3.0 3.5 7.1 8.1 7.9 7.7 9.0 7.6 7.2 8.1 6.7 7.4 8.4 UBE2D2 "UBC4, UbcH5B" ENSG00000131508 "Ubiquitin conjugating enzyme E2 D2" P62837 5 139526431-139628433 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.14e-1)" "unprognostic (2.75e-3)" "prognostic favourable (5.09e-5)" "prognostic favourable (5.90e-4)" "unprognostic (2.33e-1)" "unprognostic (8.19e-3)" "prognostic unfavourable (9.63e-7)" "unprognostic (7.41e-3)" "unprognostic (2.17e-1)" "unprognostic (1.21e-1)" "unprognostic (9.33e-2)" "unprognostic (1.41e-3)" "prognostic unfavourable (2.09e-5)" "unprognostic (8.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.20e-1)" "unprognostic (1.07e-1)" 35.6 25.0 41.2 31.5 39.9 44.2 35.9 31.9 49.6 43.9 50.4 35.5 31.5 22.2 35.5 52.2 44.8 47.6 27.1 34.8 39.5 40.5 37.2 39.5 34.8 55.6 40.5 36.1 35.3 41.7 23.8 35.3 33.6 35.9 30.8 46.4 30.7 30.5 37.9 80.6 33.2 37.4 39.3 41.9 41.3 29.1 68.0 29.3 71.0 34.4 31.2 64.5 42.2 36.1 34.3 39.3 40.8 23.0 22.5 41.7 19.5 36.5 24.4 42.8 29.9 28.9 37.1 27.4 38.7 36.2 45.6 53.4 62.8 34.8 52.3 51.0 39.9 23.2 42.0 65.2 61.1 33.7 24.5 29.6 27.0 36.0 56.6 28.9 26.4 29.1 33.7 45.2 67.7 48.6 25.6 44.8 42.2 36.7 44.6 41.2 23.5 26.6 34.0 44.5 37.8 47.9 43.3 39.0 25.8 33.8 43.5 61.4 27.2 25.7 31.8 34.8 19.4 28.9 47.2 32.2 52.3 73.3 24.9 47.7 27.7 14.8 20.9 40.8 22.6 18.8 24.7 34.1 32.7 31.7 23.4 34.3 41.7 35.2 34.5 22.5 23.0 39.3 40.0 19.5 41.2 39.9 31.9 49.6 39.5 40.5 40.5 36.1 35.9 29.3 UBE2D3 UbcH5C ENSG00000109332 "Ubiquitin conjugating enzyme E2 D3" P61077 4 102794383-102868896 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (7.43e-2)" "unprognostic (3.19e-1)" "unprognostic (1.27e-2)" "unprognostic (5.78e-2)" "unprognostic (6.44e-2)" "unprognostic (4.96e-2)" "unprognostic (1.17e-1)" "unprognostic (8.44e-3)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.75e-2)" "unprognostic (3.31e-2)" "prognostic favourable (4.51e-4)" "unprognostic (5.08e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (1.34e-2)" 67.2 70.6 39.1 52.7 44.6 132.7 70.4 36.9 50.9 45.5 51.8 37.5 38.4 49.3 46.3 39.1 63.2 45.7 47.5 72.5 37.3 39.5 63.0 91.9 67.5 68.1 43.4 36.9 60.6 53.4 42.8 49.1 66.5 45.2 49.6 48.5 38.4 46.7 43.3 91.1 53.2 58.9 48.4 44.4 68.2 49.5 40.0 42.2 88.8 66.3 55.4 61.4 74.6 81.4 24.7 31.2 118.0 36.2 29.7 33.2 50.9 52.5 30.1 50.3 40.6 53.7 77.6 43.3 53.6 71.4 47.8 45.2 45.2 75.1 56.4 35.1 54.3 30.2 53.6 71.9 65.9 52.3 27.0 51.3 31.0 36.8 56.4 72.1 44.2 58.9 45.6 52.7 73.9 62.0 64.4 57.6 63.6 42.5 105.7 41.1 36.4 30.2 55.8 49.4 40.7 48.2 50.3 50.8 42.8 32.9 84.5 60.4 35.1 42.7 56.9 50.1 42.9 32.8 48.6 51.1 65.8 86.2 53.4 40.2 53.7 71.1 35.9 54.6 25.1 36.1 33.2 24.7 31.8 29.6 31.2 20.1 32.6 29.7 118.0 29.7 36.2 21.5 32.6 50.9 39.1 44.6 36.9 50.9 37.3 39.5 43.4 36.9 45.2 42.2 UBE2D4 HBUCE1 ENSG00000078967 "Ubiquitin conjugating enzyme E2 D4 (putative)" Q9Y2X8 7 43926438-43956136 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 48.6" "Cell line enhanced" "Detected in all" "SH-SY5Y: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (9.95e-3)" "unprognostic (6.76e-2)" "unprognostic (6.87e-2)" "unprognostic (8.94e-2)" "unprognostic (8.24e-2)" "unprognostic (5.24e-2)" "unprognostic (2.42e-1)" "unprognostic (3.58e-3)" "unprognostic (4.74e-2)" "unprognostic (5.04e-2)" "prognostic favourable (4.86e-4)" "prognostic favourable (5.77e-4)" "prognostic favourable (6.51e-4)" "unprognostic (1.11e-1)" "unprognostic (8.74e-3)" "unprognostic (1.89e-1)" "unprognostic (1.34e-1)" 10.1 13.1 14.7 5.0 13.3 4.5 9.1 13.8 17.4 8.8 7.6 11.4 7.9 5.3 7.5 11.2 8.0 9.0 7.2 23.8 14.2 10.0 12.7 15.3 8.4 5.3 12.1 9.4 7.9 17.4 8.7 6.9 5.9 11.9 8.7 6.2 8.1 10.6 9.1 48.6 9.4 5.3 10.3 12.8 7.3 6.5 5.1 6.1 2.7 9.6 16.1 5.7 7.7 6.5 10.7 11.8 12.9 20.5 7.7 14.0 6.7 3.7 3.2 1.9 8.9 9.2 3.7 1.5 1.9 4.6 2.4 3.1 1.7 4.5 3.7 5.2 4.9 4.3 2.5 2.0 3.6 8.1 4.1 3.9 4.9 4.3 3.4 8.5 8.0 2.9 4.3 2.7 4.1 2.9 4.3 7.6 3.2 2.4 5.0 4.9 4.3 4.1 3.1 2.7 5.6 5.0 4.6 7.3 24.7 3.9 7.9 2.9 3.9 2.6 2.5 1.6 4.9 3.3 5.4 11.0 8.2 1.8 4.7 11.2 8.7 6.3 11.7 12.9 9.3 18.4 9.5 10.3 11.6 10.5 11.8 10.7 14.0 11.5 1.1 7.7 20.5 10.2 9.4 6.7 14.7 13.3 13.8 17.4 14.2 10.0 12.1 9.4 11.9 6.1 UBE2E1 UbcH6 ENSG00000170142 "Ubiquitin conjugating enzyme E2 E1" P51965 3 23805903-23891316 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030445, CAB073413" Approved Approved Nucleoplasm Nucleoplasm "CAB073413: , HPA030445: AB_10669599" "unprognostic (7.50e-2)" "unprognostic (2.78e-2)" "unprognostic (7.91e-3)" "unprognostic (7.13e-2)" "unprognostic (6.74e-3)" "unprognostic (1.74e-1)" "prognostic unfavourable (9.97e-7)" "unprognostic (3.69e-2)" "unprognostic (3.53e-2)" "unprognostic (1.34e-2)" "unprognostic (5.36e-3)" "unprognostic (2.70e-2)" "unprognostic (2.40e-2)" "unprognostic (1.94e-1)" "unprognostic (2.94e-1)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" 32.0 28.1 50.8 34.7 44.4 56.1 52.6 38.7 43.4 41.9 40.6 32.4 27.5 23.9 35.3 35.6 57.9 29.5 29.9 58.5 47.3 43.2 33.6 34.0 34.9 44.9 52.0 36.9 36.5 32.0 41.6 22.5 44.5 38.1 38.5 37.8 23.2 30.3 36.4 52.2 33.3 25.8 44.1 55.6 36.3 29.9 24.3 43.3 33.8 41.4 38.0 47.3 52.2 46.3 6.7 7.6 6.8 9.1 7.0 7.2 4.1 33.3 21.0 33.2 16.5 20.3 29.6 29.0 25.3 39.3 28.4 38.1 15.8 37.0 29.5 21.4 24.3 10.8 39.1 31.2 37.3 35.7 43.7 40.8 15.8 19.3 29.2 40.2 21.8 27.9 29.5 36.2 48.7 45.1 28.5 33.0 22.7 17.2 28.2 43.7 48.7 53.9 31.4 14.5 85.0 44.2 23.8 9.6 34.5 22.6 21.0 36.4 23.6 53.2 29.3 20.9 25.9 15.4 18.7 27.5 16.3 58.5 22.5 38.6 16.1 2.4 8.4 6.8 4.5 9.1 6.5 6.5 5.4 3.8 7.3 6.7 7.2 4.3 3.3 7.0 5.8 7.6 3.9 4.1 50.8 44.4 38.7 43.4 47.3 43.2 52.0 36.9 38.1 43.3 UBE2E2 "FLJ25157, UbcH8" ENSG00000182247 "Ubiquitin conjugating enzyme E2 E2" Q96LR5 3 23203020-23591793 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 15.2;intermediate monocyte: 17.8;memory B-cell: 12.3;myeloid DC: 20.9;naive B-cell: 14.8;non-classical monocyte: 18.3;plasmacytoid DC: 27.1" "Group enriched" "Detected in many" 6 "B-cells: 14.8;dendritic cells: 27.1;monocytes: 18.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA028872, HPA030445, CAB073417" Approved Approved Nucleoplasm Nucleoplasm "CAB073417: , HPA003303: AB_1858521, HPA028872: AB_10966277, HPA030445: AB_10669599" "unprognostic (2.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-2)" "unprognostic (3.68e-3)" "unprognostic (3.74e-2)" "unprognostic (1.70e-1)" "unprognostic (9.19e-3)" "unprognostic (3.11e-3)" "unprognostic (1.32e-1)" "unprognostic (1.20e-1)" "unprognostic (4.20e-1)" "unprognostic (4.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.44e-2)" "unprognostic (2.68e-2)" "unprognostic (3.11e-2)" "unprognostic (6.11e-3)" 22.7 11.4 19.2 12.0 23.3 7.6 15.9 18.8 32.7 22.4 14.5 20.8 7.5 5.9 17.7 31.9 19.7 12.0 18.5 23.4 21.3 21.8 19.1 15.8 16.7 17.7 14.1 19.7 19.0 9.8 15.5 14.4 9.0 20.9 18.2 6.4 8.4 11.2 17.0 32.0 14.8 7.2 22.4 17.6 15.9 11.1 17.8 13.3 14.8 16.8 11.1 14.5 17.0 16.2 14.8 27.1 0.4 18.3 0.8 3.6 5.2 16.7 6.0 16.0 0.3 14.2 15.9 14.5 10.6 18.1 10.0 14.1 1.7 13.8 14.6 7.3 9.3 1.6 11.6 16.5 12.9 0.1 11.6 0.0 7.2 2.0 10.2 0.0 11.7 12.5 17.4 14.3 24.2 9.6 0.8 15.6 9.0 2.6 7.6 3.3 11.3 8.8 16.0 6.2 16.7 9.7 0.4 4.1 8.5 11.7 6.9 0.2 14.7 9.7 8.3 9.9 14.0 6.6 12.0 15.0 4.9 21.5 9.3 6.6 2.7 0.0 15.2 0.0 0.2 17.8 0.3 12.3 0.5 0.2 20.9 14.8 3.6 1.3 0.4 0.8 18.3 27.1 0.2 5.2 19.2 23.3 18.8 32.7 21.3 21.8 14.1 19.7 20.9 13.3 UBE2E3 UbcH9 ENSG00000170035 "Ubiquitin conjugating enzyme E2 E3" Q969T4 2 180967248-181076585 "Enzymes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA030445" Approved "HPA003303: AB_1858521, HPA030445: AB_10669599" "unprognostic (8.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-2)" "unprognostic (2.23e-1)" "prognostic unfavourable (8.08e-5)" "prognostic unfavourable (9.11e-4)" "unprognostic (1.00e-3)" "unprognostic (4.99e-2)" "unprognostic (8.46e-2)" "prognostic unfavourable (1.78e-5)" "unprognostic (8.75e-2)" "unprognostic (3.86e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (4.40e-1)" 29.1 23.9 35.6 21.1 33.0 20.1 49.7 37.4 62.9 30.4 25.2 18.6 19.8 23.0 26.6 29.2 23.1 29.7 35.9 37.8 43.9 32.5 36.0 29.6 28.5 37.6 31.5 31.9 27.7 29.9 42.9 21.6 23.9 30.5 20.9 27.8 24.6 26.3 22.7 76.8 28.1 26.2 24.1 41.3 20.4 28.3 28.1 21.5 30.9 37.4 27.8 23.0 31.8 23.0 7.7 29.7 25.6 16.9 8.5 12.0 9.6 17.2 7.9 113.1 3.9 33.6 43.4 18.0 23.2 29.4 19.6 24.5 8.5 21.1 8.5 20.4 31.6 7.4 68.2 23.8 35.3 20.8 20.6 29.5 10.7 23.6 16.2 13.6 14.1 17.1 22.2 17.1 16.6 25.8 15.0 16.0 48.1 9.5 24.8 12.8 21.6 37.4 24.3 11.5 20.3 33.3 15.3 19.7 22.0 10.1 10.7 9.5 5.8 20.2 23.7 38.2 25.2 22.3 27.0 14.0 8.9 24.0 37.7 5.4 21.1 13.0 14.0 25.6 9.3 12.3 11.1 7.7 7.3 12.0 9.2 4.9 7.8 8.5 13.2 8.5 16.9 29.7 2.8 9.6 35.6 33.0 37.4 62.9 43.9 32.5 31.5 31.9 30.5 21.5 UBE2F NCE2 ENSG00000184182 "Ubiquitin conjugating enzyme E2 F (putative)" Q969M7 2 237966827-238042782 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037444 Approved Approved Cytosol Cytosol "HPA037444: AB_10672491" "unprognostic (1.73e-1)" "unprognostic (1.65e-1)" "unprognostic (3.80e-2)" "unprognostic (6.92e-3)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "prognostic unfavourable (2.72e-4)" "unprognostic (3.43e-3)" "unprognostic (6.64e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" "unprognostic (2.04e-1)" "prognostic unfavourable (1.59e-7)" "unprognostic (2.04e-2)" "unprognostic (6.39e-2)" "unprognostic (3.60e-2)" "unprognostic (2.51e-1)" 14.5 18.4 21.3 13.6 17.6 19.9 17.2 12.2 19.8 16.7 15.8 17.7 12.3 13.6 14.7 32.2 25.0 11.0 16.3 34.6 20.2 21.6 14.6 24.1 12.9 26.4 23.4 10.1 10.4 62.8 16.3 13.2 22.2 24.2 14.9 19.6 11.4 15.3 18.2 32.1 10.3 17.9 20.2 20.2 14.6 15.1 13.9 16.8 15.8 32.9 17.4 17.7 18.7 16.4 10.9 23.1 35.6 30.0 39.9 29.1 24.6 13.7 7.9 18.1 18.5 23.6 28.8 25.6 13.0 18.6 14.7 15.1 8.6 8.8 7.1 4.7 29.0 11.7 20.5 28.2 22.9 10.8 8.0 9.8 10.0 27.9 29.7 4.1 23.1 16.5 46.6 19.3 29.5 25.9 29.8 4.6 26.5 20.6 11.1 18.0 19.9 12.0 13.5 12.0 12.7 22.1 5.8 12.1 18.1 15.2 11.5 23.9 10.4 17.1 16.1 16.2 14.2 18.3 13.9 5.7 4.4 13.9 19.2 12.5 11.9 35.6 21.0 25.2 29.1 27.6 11.5 10.9 19.9 17.6 18.6 10.1 18.6 18.8 15.6 39.9 30.0 23.1 20.5 24.6 21.3 17.6 12.2 19.8 20.2 21.6 23.4 10.1 24.2 16.8 UBE2G1 "UBC7, UBE2G" ENSG00000132388 "Ubiquitin conjugating enzyme E2 G1" P62253 17 4269259-4366628 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 95.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045681, HPA050551" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA045681: , HPA050551: " "unprognostic (1.57e-3)" "unprognostic (1.94e-1)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (5.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.80e-1)" "unprognostic (1.67e-2)" "unprognostic (9.99e-2)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (3.97e-2)" "unprognostic (6.50e-2)" 10.8 11.1 12.6 17.8 13.5 14.3 11.2 11.6 15.3 13.0 19.4 17.8 8.9 11.9 13.3 8.5 27.4 9.2 9.7 26.9 13.5 11.2 14.6 17.7 8.9 18.7 15.2 9.7 9.1 17.1 12.0 6.0 11.4 14.5 14.0 13.3 8.8 11.9 12.0 95.6 14.1 16.6 14.6 19.4 15.0 11.9 11.8 13.6 21.3 12.5 20.7 23.3 17.7 16.5 23.7 13.1 24.4 11.5 20.5 20.6 13.1 21.2 23.0 21.5 15.7 17.6 18.7 30.7 20.7 16.7 19.8 17.4 15.8 10.9 33.3 21.8 20.3 23.0 26.7 19.2 31.9 17.5 21.8 12.4 12.2 18.0 17.3 18.0 23.6 15.9 28.8 18.7 27.3 26.4 21.8 36.1 16.2 9.5 22.9 16.6 23.7 12.0 29.8 11.4 30.4 23.0 14.0 9.3 17.4 19.5 17.0 16.1 16.7 11.8 19.8 19.9 15.2 23.2 23.1 14.0 16.4 47.1 15.3 16.9 15.2 8.1 10.3 24.4 15.4 10.8 20.6 23.7 20.1 20.1 13.1 15.5 20.2 20.5 18.6 20.5 11.5 9.6 18.3 13.1 12.6 13.5 11.6 15.3 13.5 11.2 15.2 9.7 14.5 13.6 UBE2G2 UBC7 ENSG00000184787 "Ubiquitin conjugating enzyme E2 G2" P60604 21 44768580-44802019 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003332 Approved "HPA003332: AB_1858525" "unprognostic (7.58e-2)" "unprognostic (5.41e-2)" "unprognostic (1.58e-2)" "unprognostic (4.45e-2)" "unprognostic (6.30e-2)" "unprognostic (4.67e-2)" "unprognostic (5.99e-2)" "unprognostic (3.79e-3)" "unprognostic (6.93e-3)" "unprognostic (7.02e-2)" "unprognostic (1.40e-2)" "unprognostic (6.98e-3)" "prognostic unfavourable (7.02e-5)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (2.75e-2)" "unprognostic (3.55e-2)" 30.9 20.7 18.9 22.8 20.9 25.8 21.1 21.0 21.6 18.9 22.7 20.5 19.8 14.9 22.2 18.4 19.3 20.5 18.0 37.1 18.3 17.1 26.2 27.3 19.7 19.7 19.0 17.0 18.1 30.2 22.1 26.0 17.0 18.9 18.3 16.5 18.6 15.4 28.3 50.8 15.6 16.9 28.5 17.8 23.8 20.2 14.0 18.8 18.4 20.6 18.7 21.6 20.9 18.9 11.9 17.5 5.9 13.0 14.0 17.3 12.1 15.6 3.2 10.8 13.9 14.8 6.5 9.9 11.1 8.6 9.7 10.6 12.4 2.1 20.3 10.6 11.0 6.3 15.8 13.4 8.8 19.0 16.3 33.0 2.3 10.0 11.7 24.3 5.7 10.4 15.9 13.0 12.7 15.2 30.6 14.2 13.3 7.0 26.9 2.9 28.1 14.0 22.1 10.0 18.1 12.7 8.4 12.6 22.4 15.6 5.1 16.0 4.9 21.2 10.8 9.4 6.7 8.7 17.9 22.3 43.8 20.1 9.4 28.8 11.0 2.3 11.6 5.9 16.0 11.8 17.3 11.8 14.7 16.2 12.5 11.9 15.7 16.6 3.6 14.0 13.0 17.5 14.6 12.1 18.9 20.9 21.0 19.3 18.3 17.1 19.0 17.0 18.9 18.8 UBE2H "GID3, UBC8, UBCH" ENSG00000186591 "Ubiquitin conjugating enzyme E2 H" P62256 7 129830732-129952949 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003302 Approved Supported Mitochondria Mitochondria "HPA003302: AB_1858526" "unprognostic (1.15e-1)" "unprognostic (5.85e-2)" "unprognostic (5.67e-3)" "unprognostic (2.76e-1)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (6.19e-2)" "prognostic unfavourable (2.33e-5)" "unprognostic (1.13e-1)" "unprognostic (3.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-1)" "unprognostic (1.23e-1)" 29.0 49.9 31.1 16.6 31.0 22.5 24.5 36.1 30.2 31.1 27.3 33.2 26.6 15.2 35.5 25.3 32.1 29.4 26.6 61.0 26.4 25.4 27.6 28.1 26.3 17.5 28.1 23.4 27.6 52.3 41.8 29.5 37.9 33.3 24.1 16.8 22.9 28.5 28.8 46.3 21.3 16.5 31.5 26.2 19.1 22.7 24.7 29.5 24.7 37.7 23.6 29.5 25.5 34.3 6.1 3.7 7.8 2.2 1.3 6.5 1.9 22.7 12.3 14.6 14.8 36.4 31.3 25.3 21.1 27.2 12.9 14.4 6.6 24.4 9.4 26.4 20.7 17.3 12.5 22.4 16.9 11.6 6.6 3.2 18.1 7.9 28.6 6.5 10.4 42.0 29.8 17.4 28.0 25.1 7.7 27.4 19.9 8.1 8.6 7.1 23.0 14.7 6.7 7.5 20.1 27.0 29.9 5.6 16.9 19.3 43.2 11.3 4.5 6.4 25.5 14.1 7.1 19.8 20.9 25.0 18.0 15.6 28.0 7.8 13.7 3.5 2.2 5.1 4.7 1.7 6.4 3.8 4.7 4.2 2.0 6.1 6.0 6.4 7.8 1.3 2.1 3.7 6.5 1.9 31.1 31.0 36.1 30.2 26.4 25.4 28.1 23.4 33.3 29.5 UBE2J1 "CGI-76, HSPC153, NCUBE1, UBC6" ENSG00000198833 "Ubiquitin conjugating enzyme E2 J1" Q9Y385 6 89326625-89352848 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 62.5;Karpas-707: 54.0;U-266/70: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003509, CAB073419" Enhanced "CAB073419: , HPA003509: AB_1858531" "unprognostic (1.82e-1)" "unprognostic (3.20e-2)" "unprognostic (1.55e-3)" "prognostic favourable (2.87e-4)" "unprognostic (3.41e-1)" "unprognostic (7.93e-3)" "prognostic unfavourable (6.90e-5)" "unprognostic (1.19e-1)" "unprognostic (9.36e-2)" "prognostic favourable (7.43e-4)" "unprognostic (1.74e-1)" "unprognostic (9.33e-2)" "prognostic unfavourable (1.11e-4)" "unprognostic (5.11e-2)" "unprognostic (2.83e-1)" "unprognostic (3.87e-2)" "unprognostic (9.38e-2)" 18.7 17.3 14.6 47.1 15.4 52.7 28.2 19.1 13.6 18.8 25.9 11.3 24.4 28.0 19.5 18.4 19.2 18.0 19.9 17.1 14.4 14.7 18.7 33.5 20.4 52.0 17.0 9.5 17.2 46.1 11.5 13.6 27.5 13.0 22.9 26.3 10.7 42.1 33.2 12.5 11.3 36.3 17.9 18.9 45.8 24.4 17.7 14.4 42.5 17.6 16.4 47.7 21.7 21.4 20.7 23.7 15.9 17.8 6.4 6.4 6.1 8.1 2.8 7.9 10.1 8.3 10.8 0.0 13.0 11.5 8.1 8.9 4.6 5.1 62.5 7.3 13.4 3.3 5.1 7.5 13.2 8.7 8.0 11.3 3.7 7.6 22.1 14.2 7.4 8.2 7.6 6.7 11.6 18.0 9.1 54.0 9.4 5.0 5.9 10.9 2.7 4.1 23.3 10.2 29.9 10.1 5.7 4.0 8.1 5.5 12.2 12.0 4.8 31.6 12.0 4.5 4.3 8.0 9.9 60.7 30.1 17.1 8.9 10.3 7.4 10.3 6.6 12.3 3.4 11.1 4.0 20.7 4.6 4.2 6.5 13.4 4.3 3.9 15.9 6.4 17.8 23.7 6.4 6.1 14.6 15.4 19.1 13.6 14.4 14.7 17.0 9.5 13.0 14.4 UBE2K "HIP2, HYPG, UBC1" ENSG00000078140 "Ubiquitin conjugating enzyme E2 K" P61086 4 39698044-39782792 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028869, CAB033212, CAB033515" Supported Supported "Intermediate filaments,Actin filaments,Cytosol" 150000 Cytosol "Intermediate filaments, Actin filaments" "CAB033212: AB_2272506, CAB033515: AB_2304024, HPA028869: AB_10602487" "unprognostic (1.14e-2)" "unprognostic (6.02e-2)" "unprognostic (2.42e-3)" "unprognostic (3.06e-1)" "unprognostic (6.81e-2)" "unprognostic (2.05e-1)" "unprognostic (5.05e-3)" "unprognostic (1.44e-2)" "unprognostic (2.71e-3)" "unprognostic (1.01e-1)" "prognostic unfavourable (8.60e-4)" "unprognostic (1.08e-1)" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (4.10e-3)" 27.2 21.8 27.0 21.2 27.6 17.3 21.6 38.6 40.7 17.0 33.2 11.8 14.1 29.1 19.9 18.5 29.9 14.9 18.5 28.1 27.7 26.8 26.6 44.5 17.1 17.9 24.1 26.4 16.9 15.8 18.9 26.9 29.8 25.2 19.7 24.0 13.4 18.4 17.3 31.8 22.0 24.6 18.8 19.2 16.9 29.3 16.0 15.9 21.3 23.6 19.7 18.8 22.8 20.4 17.6 23.7 20.6 19.9 10.9 14.1 8.9 23.8 24.5 13.2 12.5 8.3 7.8 22.5 32.9 7.0 8.8 9.3 37.0 24.6 29.8 29.0 9.2 10.1 25.4 14.3 14.2 20.0 18.2 38.6 24.8 32.0 10.4 41.4 21.9 7.3 16.2 12.4 13.4 11.5 39.2 10.7 9.1 23.1 28.9 23.0 17.6 18.7 17.1 39.7 11.2 12.3 33.3 27.4 12.1 24.6 9.3 14.7 12.0 13.9 31.5 13.8 29.3 16.4 30.2 15.2 44.3 32.8 7.2 26.6 16.1 13.9 16.6 20.6 13.5 14.3 12.7 17.6 14.1 12.6 16.6 12.5 10.7 12.0 13.3 10.9 19.9 23.7 13.7 8.9 27.0 27.6 38.6 37.7 27.7 26.8 24.1 26.4 25.2 15.9 UBE2L3 UBCH7 ENSG00000185651 "Ubiquitin conjugating enzyme E2 L3" P68036 22 21549447-21624034 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA045609, HPA062415" Approved Approved Nucleoplasm,Cytosol 8800000 "Nucleoplasm, Cytosol" "HPA045609: AB_10961322, HPA062415: " "unprognostic (4.90e-2)" "unprognostic (3.05e-1)" "unprognostic (1.92e-2)" "unprognostic (1.07e-2)" "unprognostic (2.74e-2)" "unprognostic (9.99e-3)" "prognostic unfavourable (1.29e-4)" "unprognostic (3.28e-2)" "unprognostic (3.65e-2)" "prognostic favourable (3.82e-6)" "unprognostic (3.53e-2)" "unprognostic (4.55e-2)" "unprognostic (3.18e-2)" "unprognostic (4.66e-2)" "unprognostic (5.09e-2)" "unprognostic (2.77e-1)" "unprognostic (3.15e-3)" 27.8 34.9 34.8 23.5 29.6 31.3 24.9 25.5 36.9 25.9 27.7 38.4 22.8 26.4 25.6 29.2 38.0 26.9 23.0 33.0 30.7 30.8 27.4 36.0 23.5 32.5 34.3 33.1 24.3 23.9 24.3 21.7 30.1 36.9 27.5 31.7 29.3 30.6 26.7 43.5 23.9 34.4 33.1 36.2 28.5 25.1 35.7 22.6 25.3 25.0 32.4 33.9 28.4 22.2 34.7 49.9 46.1 45.8 34.6 46.9 54.9 24.4 14.1 20.7 16.1 22.6 20.2 11.9 20.6 23.6 26.6 25.3 16.0 11.8 23.1 10.4 27.3 21.0 27.5 22.4 26.5 23.0 29.7 26.7 13.8 19.1 15.1 38.1 19.3 17.8 19.6 19.2 14.0 29.8 107.9 12.4 28.6 18.0 19.8 27.6 15.2 14.9 16.2 31.1 6.3 24.9 19.7 18.6 13.8 16.4 20.7 18.9 12.9 21.1 21.3 18.8 24.2 15.9 21.0 12.1 19.5 21.1 25.5 17.7 17.8 30.8 40.4 46.1 41.4 45.8 38.8 34.7 39.6 44.2 49.9 31.2 34.5 41.6 34.2 34.6 37.6 48.4 46.9 54.9 34.8 29.6 25.5 36.9 30.7 30.8 34.3 33.1 36.9 22.6 UBE2L5 UBE2L5P ENSG00000236444 "Ubiquitin conjugating enzyme E2 L5" 13 30422488-30428616 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "testis: 31.5" "Low cell line specificity" "Detected in some" "Low cancer specificity" "Detected in single" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA045609, HPA062415" Approved Uncertain Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA045609: AB_10961322, HPA062415: " "unprognostic (2.09e-1)" "unprognostic (1.18e-2)" "unprognostic (8.01e-3)" "unprognostic (6.41e-4)" "unprognostic (1.78e-1)" "unprognostic (7.13e-2)" "unprognostic (2.20e-1)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (6.49e-3)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (3.50e-2)" "unprognostic (9.37e-2)" "unprognostic (2.60e-1)" "unprognostic (2.44e-2)" "unprognostic (8.75e-2)" 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.3 0.3 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.7 0.3 0.2 0.2 0.1 0.2 0.5 0.3 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 31.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 1.9 2.7 3.6 1.9 2.0 2.8 0.6 0.3 1.2 1.6 0.6 0.6 0.6 1.1 0.6 0.4 0.2 0.0 3.0 1.4 0.5 1.3 0.6 0.8 0.4 1.1 2.4 0.6 0.4 0.8 0.2 0.2 0.7 1.5 0.2 0.3 0.6 0.2 0.9 0.7 1.3 0.3 0.0 1.6 2.5 1.3 0.2 0.4 0.6 0.4 0.9 1.5 1.2 0.3 0.4 0.1 1.8 0.6 2.4 0.0 0.7 0.5 0.7 1.1 1.5 0.3 1.6 1.0 0.9 0.4 1.8 1.1 1.9 1.4 3.6 1.2 3.2 1.5 1.6 1.5 1.7 1.4 2.0 2.7 1.9 1.6 1.9 2.0 2.8 UBE2L6 UBCH8 ENSG00000156587 "Ubiquitin conjugating enzyme E2 L6" O14933 11 57551656-57568284 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003328, CAB073407" Enhanced Approved Cytosol 34000 Cytosol "CAB073407: , HPA003328: AB_1858539" "prognostic favourable (6.75e-4)" "unprognostic (2.10e-2)" "unprognostic (1.09e-2)" "unprognostic (2.93e-2)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (3.13e-2)" "unprognostic (4.74e-2)" "unprognostic (1.36e-2)" "unprognostic (1.37e-3)" "prognostic unfavourable (4.88e-4)" "unprognostic (3.07e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" "unprognostic (4.17e-2)" "unprognostic (1.88e-2)" "unprognostic (6.42e-2)" 31.1 31.0 32.0 34.1 28.6 30.4 40.4 18.2 25.6 23.3 19.1 17.0 17.1 19.0 21.9 30.0 19.9 28.6 27.4 18.4 23.5 27.4 28.3 55.1 50.5 45.0 28.9 20.4 27.1 21.8 17.9 18.5 21.7 25.8 26.0 18.8 18.7 42.8 22.2 10.1 15.9 23.5 28.3 23.6 47.9 21.4 7.7 23.6 44.0 33.6 15.1 34.4 33.0 49.0 49.2 53.6 113.6 83.4 61.2 66.4 112.6 8.7 4.4 14.9 4.7 31.6 39.4 1.6 5.1 30.4 45.1 58.7 1.6 22.8 28.0 18.0 15.5 7.0 6.4 16.8 9.6 25.5 0.2 27.6 0.0 6.2 58.6 6.3 9.1 42.1 3.9 21.1 5.8 14.2 1.2 19.4 8.1 11.1 42.5 15.2 3.9 5.6 37.6 9.1 19.2 12.1 9.8 0.3 7.8 10.2 0.8 22.3 11.2 3.2 5.2 9.4 3.3 7.1 1.6 26.5 26.7 0.5 26.3 16.0 2.0 56.7 71.6 62.5 51.2 83.4 56.4 49.2 53.4 53.4 53.6 39.7 46.5 48.8 113.6 61.2 68.3 34.0 66.4 112.6 32.0 28.6 18.2 25.6 23.5 27.4 28.9 20.4 25.8 23.6 UBE2N "MGC8489, UBC13, UbcH-ben" ENSG00000177889 "Ubiquitin conjugating enzyme E2 N" P61088 12 93405673-93442262 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA044976 Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" 4600000 Nucleoplasm "Nucleoli fibrillar center" "HPA044976: " "unprognostic (1.74e-2)" "unprognostic (5.53e-1)" "unprognostic (1.26e-2)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (8.09e-2)" "prognostic unfavourable (2.41e-4)" "unprognostic (8.49e-3)" "unprognostic (2.72e-1)" "unprognostic (4.28e-3)" "unprognostic (1.07e-1)" "unprognostic (9.28e-2)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.48e-1)" "unprognostic (1.30e-3)" 24.7 25.0 29.0 28.7 39.1 29.0 21.2 29.2 44.3 18.4 26.6 15.6 15.1 20.7 23.2 20.0 30.4 19.7 17.0 27.7 31.0 33.7 25.4 22.3 19.3 36.1 27.6 34.5 17.4 17.6 13.9 18.2 24.2 34.9 23.4 22.6 13.7 18.0 18.5 35.7 19.1 20.4 21.3 24.6 21.5 19.3 83.7 17.4 32.2 15.5 16.8 35.1 22.7 18.8 53.8 35.5 29.9 39.2 29.5 57.3 51.9 35.8 26.0 43.9 28.1 17.0 16.9 30.6 50.2 26.8 40.3 33.8 46.2 15.6 73.0 11.4 29.3 28.6 48.4 36.8 38.4 60.7 25.1 49.1 14.3 40.7 21.7 58.6 32.8 17.7 15.2 24.0 30.0 31.0 54.5 11.4 41.8 29.5 57.8 54.5 57.1 36.4 45.0 35.6 35.7 33.5 54.3 42.9 39.1 26.5 31.2 24.5 40.8 36.1 32.0 27.3 22.8 24.6 36.1 19.7 53.3 62.0 10.7 31.3 33.3 29.9 27.1 28.9 31.7 35.4 36.9 53.8 40.2 39.2 35.5 38.6 36.0 34.4 8.2 29.5 39.2 26.7 57.3 51.9 29.0 39.1 29.2 44.3 31.0 33.7 27.6 34.5 34.9 17.4 UBE2O E2-230K ENSG00000175931 "Ubiquitin conjugating enzyme E2 O" Q9C0C9 17 76389451-76453206 "Enzymes, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023605 Uncertain Supported "Nucleoplasm,Nuclear bodies" 1600000 Nucleoplasm "Nuclear bodies" "HPA023605: " "unprognostic (8.75e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (8.68e-2)" "unprognostic (1.17e-1)" "unprognostic (3.22e-2)" "prognostic unfavourable (6.84e-8)" "unprognostic (3.54e-1)" "unprognostic (2.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-3)" "unprognostic (1.18e-2)" "prognostic unfavourable (4.34e-9)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" 8.5 8.5 13.8 10.2 22.6 19.2 7.3 25.2 38.1 9.4 7.2 12.2 7.4 9.9 9.9 8.2 11.7 10.8 7.1 15.4 12.7 15.2 6.5 7.6 6.6 12.8 11.7 14.6 13.9 14.4 16.4 14.3 9.8 30.6 9.4 6.0 10.5 13.4 10.4 23.0 15.2 8.2 8.0 8.0 10.8 10.8 18.1 12.2 10.9 15.8 6.9 9.2 8.6 9.1 4.9 4.1 2.7 1.7 1.5 4.0 1.9 12.9 14.9 15.2 18.7 9.6 6.1 13.2 6.1 6.6 9.9 9.7 12.9 6.6 18.4 4.3 7.5 13.1 17.7 10.5 7.1 5.2 21.8 18.6 9.7 21.6 7.9 11.2 11.3 6.2 8.6 9.5 8.2 13.4 15.5 16.4 5.0 10.7 22.2 13.0 14.1 20.0 22.0 19.6 20.2 4.4 11.1 22.6 20.3 8.9 23.2 12.2 13.3 8.1 7.9 11.7 11.0 9.9 10.0 13.6 4.4 15.5 12.8 9.4 7.6 0.0 1.7 2.7 4.0 0.8 2.2 2.6 2.6 2.0 1.0 4.9 2.1 3.0 0.4 1.5 1.0 4.1 2.3 1.9 13.8 22.6 25.2 38.1 12.7 15.2 11.7 14.6 30.6 12.2 UBE2Q1 "NICE-5, PRO3094, UBE2Q" ENSG00000160714 "Ubiquitin conjugating enzyme E2 Q1" Q7Z7E8 1 154548577-154559028 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063368 Approved Approved Nucleoplasm,Centrosome Nucleoplasm Centrosome "HPA063368: " "unprognostic (3.88e-1)" "unprognostic (2.13e-1)" "unprognostic (4.44e-3)" "unprognostic (3.64e-3)" "unprognostic (5.32e-3)" "unprognostic (6.10e-3)" "prognostic unfavourable (8.74e-4)" "unprognostic (2.92e-1)" "unprognostic (2.07e-1)" "unprognostic (9.92e-3)" "unprognostic (3.79e-2)" "unprognostic (1.46e-1)" "prognostic unfavourable (4.84e-7)" "unprognostic (2.20e-1)" "unprognostic (4.46e-1)" "prognostic favourable (1.86e-5)" "unprognostic (1.04e-2)" 17.3 18.7 26.5 16.2 29.4 24.2 19.4 26.4 29.0 20.0 21.2 18.7 8.2 16.2 18.3 25.4 20.9 21.8 18.2 17.6 24.5 25.8 25.7 27.4 23.0 26.3 22.8 21.0 21.7 27.2 21.4 29.3 24.5 27.2 21.4 25.7 18.5 19.0 19.8 19.1 21.6 21.4 21.9 19.1 26.0 20.5 30.0 22.0 25.1 21.0 14.0 29.9 19.3 18.5 3.2 5.1 8.1 3.1 4.7 6.2 1.6 18.0 15.7 22.2 16.9 22.8 23.6 19.2 17.9 27.4 23.2 18.8 17.6 19.4 22.3 25.9 25.0 15.8 26.1 20.8 20.0 22.4 16.5 17.7 14.0 17.0 28.8 28.7 28.5 22.7 27.6 18.7 21.7 29.7 14.8 27.7 29.5 28.0 17.5 21.1 30.3 26.7 20.2 15.5 23.4 25.4 19.3 22.6 31.6 18.2 34.3 29.4 20.9 43.8 20.6 15.0 16.8 17.7 19.1 33.8 25.0 29.5 16.8 20.3 22.7 8.1 2.8 5.6 4.8 3.1 4.3 3.0 4.5 5.9 2.5 3.2 5.0 5.7 4.4 4.7 2.6 5.1 6.2 1.6 26.5 29.4 26.4 29.0 24.5 25.8 22.8 21.0 27.2 22.0 UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448623-6494909 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 28.1;heart muscle: 11.3;retina: 8.2;seminal vesicle: 8.6;skeletal muscle: 21.3" "Cell line enhanced" "Detected in some" "Karpas-707: 17.8;PC-3: 14.9;SCLC-21H: 13.9;U-266/70: 33.3;U-266/84: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "eosinophil: 1.2" "Lineage enhanced" "Detected in single" "granulocytes: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favourable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" 0.6 2.3 8.6 0.8 4.2 0.3 0.9 20.7 28.1 1.0 1.8 1.0 0.5 0.7 1.4 1.8 1.0 0.5 0.8 11.3 12.6 8.2 2.6 1.1 0.4 0.7 5.2 4.6 3.6 0.8 0.3 1.3 0.3 8.7 3.1 0.8 8.2 1.0 8.6 21.3 2.4 1.0 1.3 1.4 0.4 2.2 0.9 0.0 0.0 1.9 2.0 0.5 0.5 0.9 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.8 0.0 3.0 0.0 0.0 0.2 14.9 0.1 0.0 6.6 0.0 0.0 13.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 33.3 29.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 4.2 20.7 19.4 12.6 8.2 5.2 4.6 8.7 0.0 UBE2R2 "CDC34B, FLJ20419, MGC10481, UBC3B" ENSG00000107341 "Ubiquitin conjugating enzyme E2 R2" Q712K3 9 33817567-33920404 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 21.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061000 Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA061000: " "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (7.08e-2)" "unprognostic (1.53e-1)" "unprognostic (6.55e-2)" "unprognostic (5.15e-2)" "prognostic unfavourable (4.37e-4)" "unprognostic (1.82e-3)" "unprognostic (4.61e-3)" "unprognostic (3.05e-3)" "unprognostic (2.22e-2)" "unprognostic (4.19e-1)" "unprognostic (2.01e-2)" "unprognostic (4.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (1.43e-1)" 26.1 19.7 29.4 19.7 26.8 13.9 39.3 23.7 32.3 25.6 24.1 27.9 16.3 28.0 26.1 18.4 25.3 22.3 21.8 29.2 25.5 20.3 22.1 34.5 23.0 27.1 30.5 23.2 29.8 44.5 15.7 13.9 24.6 21.6 21.0 21.4 19.3 18.7 20.8 56.1 28.1 25.7 28.5 24.2 21.6 20.8 34.5 29.6 36.7 19.5 22.5 25.7 35.8 30.5 3.3 4.2 21.9 11.6 5.0 2.1 2.4 16.3 18.0 34.6 15.0 19.1 31.2 10.6 14.6 20.3 17.1 17.1 14.4 12.3 14.0 6.0 20.3 7.3 18.1 16.6 18.8 23.0 9.6 12.0 19.8 18.3 27.2 14.3 13.1 26.4 24.7 14.0 26.5 28.7 11.3 15.1 16.9 9.5 26.9 37.6 19.7 14.9 25.0 10.5 7.2 18.1 12.4 16.2 19.5 17.0 15.2 10.9 13.4 17.4 21.4 16.5 15.0 11.4 13.5 9.6 9.0 19.5 15.8 8.3 35.5 12.4 7.5 4.1 2.0 7.5 1.3 3.1 1.9 1.6 4.2 3.3 1.9 1.7 21.9 5.0 11.6 2.6 2.1 2.4 29.4 26.8 23.7 32.3 25.5 20.3 30.5 23.2 21.6 29.6 UBE2S E2-EPF ENSG00000108106 "Ubiquitin conjugating enzyme E2 S" Q16763 19 55399745-55407777 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.0;lymphoid tissue: 60.2;testis: 69.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015228, HPA057150" Approved Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB015228: , HPA057150: " "unprognostic (2.79e-1)" "unprognostic (2.42e-1)" "unprognostic (2.57e-1)" "prognostic unfavourable (2.05e-4)" "unprognostic (9.54e-2)" "unprognostic (1.41e-1)" "prognostic unfavourable (8.00e-6)" "unprognostic (1.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.31e-1)" "unprognostic (8.08e-2)" "unprognostic (4.52e-2)" "prognostic unfavourable (8.16e-8)" "unprognostic (1.05e-1)" "unprognostic (9.51e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" 10.2 9.2 18.0 19.5 15.9 68.0 4.7 11.4 21.6 6.1 12.0 9.1 4.5 8.4 7.1 7.2 17.1 6.0 9.7 18.0 18.7 18.1 5.9 5.6 6.3 22.9 13.7 14.4 6.4 6.0 3.7 12.9 9.8 12.9 7.0 7.1 6.2 4.9 5.3 7.3 6.2 7.3 10.7 15.3 11.0 10.6 69.4 8.2 60.2 5.9 14.3 21.1 10.0 7.1 4.5 3.1 6.0 1.9 0.6 2.6 0.3 59.4 32.2 28.3 22.6 1.8 2.6 5.0 48.4 14.7 29.9 27.3 21.8 21.3 57.9 20.1 12.1 17.5 28.4 12.6 13.3 45.3 94.2 34.6 18.5 7.0 5.4 41.3 33.7 2.8 3.5 22.0 21.3 11.7 34.3 40.6 18.7 15.7 56.0 21.5 71.1 54.7 49.3 21.8 20.8 8.0 12.7 72.0 39.0 61.7 15.3 27.4 10.9 22.5 17.9 18.1 51.3 15.3 115.2 32.7 78.5 67.9 18.9 29.3 65.3 1.1 1.9 2.9 1.8 1.5 1.2 4.5 2.6 2.6 1.5 1.6 2.5 1.5 6.0 0.6 0.9 3.1 1.0 0.3 18.0 15.9 11.4 21.6 18.7 18.1 13.7 14.4 12.9 8.2 UBE2T "FANCT, HSPC150" ENSG00000077152 "Ubiquitin conjugating enzyme E2 T" Q9NPD8 1 202331657-202341980 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002831 Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA002831: AB_1080445" "unprognostic (2.38e-3)" "unprognostic (6.37e-2)" "unprognostic (5.27e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-1)" "unprognostic (6.13e-3)" "prognostic unfavourable (4.79e-6)" "unprognostic (1.71e-2)" "unprognostic (2.32e-2)" "prognostic favourable (6.90e-6)" "unprognostic (6.28e-3)" "unprognostic (2.85e-2)" "prognostic unfavourable (2.22e-16)" "unprognostic (5.37e-3)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" 1.9 4.2 9.6 8.5 12.2 20.8 3.9 4.4 13.5 3.5 11.2 0.7 17.2 7.5 4.3 4.1 10.3 2.9 3.0 8.8 8.8 11.2 4.5 2.8 3.1 15.2 8.7 8.2 1.3 0.9 2.4 3.1 8.7 8.2 2.2 13.9 1.9 2.8 7.0 13.1 4.5 6.9 8.1 3.4 6.7 4.0 16.0 1.8 46.8 2.6 12.8 15.3 6.3 4.5 9.0 3.6 1.7 8.6 1.1 11.1 2.9 30.3 29.0 43.2 20.4 4.0 7.4 24.7 33.2 18.6 38.0 26.8 20.6 37.3 35.4 13.2 12.1 24.8 39.9 19.5 34.3 32.1 22.8 21.6 15.8 23.5 1.8 25.9 26.4 2.6 4.7 29.9 12.4 22.0 27.3 29.3 29.7 28.3 46.3 33.0 16.7 14.8 35.9 46.0 30.8 14.5 14.6 34.0 34.7 23.2 28.6 11.1 30.1 16.4 10.8 17.1 27.4 29.9 39.4 14.9 29.0 45.1 17.0 27.0 35.5 0.0 0.8 1.7 3.7 2.4 2.8 9.0 5.0 3.9 1.7 6.3 7.3 8.0 0.0 1.1 8.6 3.6 11.1 2.9 9.6 12.2 4.4 13.5 8.8 11.2 8.7 8.2 8.2 1.8 UBE2W "FLJ11011, UBC-16" ENSG00000104343 "Ubiquitin conjugating enzyme E2 W" Q96B02 8 73780097-73878910 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045161, HPA073181" Uncertain Approved Nucleoli Nucleoli "HPA045161: AB_10960706, HPA073181: " "unprognostic (5.36e-2)" "unprognostic (1.87e-1)" "unprognostic (7.52e-2)" "unprognostic (1.32e-3)" "unprognostic (3.17e-1)" "unprognostic (9.74e-2)" "unprognostic (3.09e-2)" "unprognostic (6.93e-3)" "unprognostic (1.83e-1)" "unprognostic (3.47e-1)" "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" "unprognostic (5.01e-2)" "unprognostic (4.38e-2)" "unprognostic (9.31e-2)" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" 15.2 14.2 13.5 13.3 21.8 17.5 13.4 18.9 24.4 12.0 9.8 11.3 11.0 7.9 13.4 10.5 16.6 9.4 15.2 14.8 19.0 12.3 21.9 23.4 13.6 11.6 11.6 13.0 11.8 12.7 18.4 20.9 13.6 18.4 12.0 11.5 9.5 12.2 10.6 16.4 10.6 8.5 12.8 12.6 13.6 10.0 16.4 12.3 14.7 17.1 4.8 12.9 16.8 12.8 5.0 8.1 23.0 9.4 4.7 4.3 4.8 8.5 5.6 6.9 7.5 12.1 12.4 6.0 9.4 10.4 9.1 9.5 4.6 9.6 4.0 7.8 9.8 8.7 10.2 9.6 15.2 6.4 6.2 8.1 5.8 7.1 8.2 4.4 11.5 9.7 10.8 10.6 19.0 11.0 4.0 8.6 13.8 6.8 9.6 4.8 5.3 11.1 2.9 7.1 3.4 16.9 9.4 5.1 5.6 7.5 24.5 11.3 11.5 7.9 9.8 11.0 8.4 8.3 6.9 7.3 7.5 2.9 9.6 7.1 9.4 12.9 9.4 11.5 3.5 8.8 4.3 5.0 3.6 2.6 6.3 4.3 3.2 3.8 23.0 4.7 9.4 8.1 4.0 4.8 13.5 21.8 18.9 24.4 19.0 12.3 11.6 13.0 18.4 12.3 UBE2Z "FLJ13855, USE1" ENSG00000159202 "Ubiquitin conjugating enzyme E2 Z" Q9H832 17 48908369-48929056 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007922 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA007922: AB_1858551" "unprognostic (6.85e-2)" "unprognostic (5.72e-3)" "prognostic favourable (4.62e-4)" "unprognostic (9.11e-2)" "unprognostic (3.71e-3)" "unprognostic (1.76e-1)" "prognostic unfavourable (5.57e-4)" "unprognostic (2.32e-2)" "unprognostic (5.26e-2)" "unprognostic (8.66e-2)" "unprognostic (9.17e-3)" "unprognostic (3.48e-2)" "prognostic unfavourable (1.05e-4)" "unprognostic (2.63e-2)" "unprognostic (2.11e-2)" "unprognostic (1.91e-2)" "unprognostic (1.52e-1)" 27.1 40.6 29.2 27.7 37.0 22.2 28.8 34.4 50.2 33.7 28.9 59.9 45.1 26.6 36.2 49.5 37.2 36.0 28.0 28.7 30.5 29.2 32.1 25.6 29.2 30.9 46.6 28.0 32.5 29.5 36.6 28.0 35.0 39.7 32.9 32.5 28.4 33.3 43.2 24.1 35.9 30.5 39.1 32.7 36.6 29.4 22.4 43.4 29.4 39.8 22.2 44.2 28.8 32.2 12.8 10.1 11.0 14.5 7.4 13.1 8.6 24.8 30.9 11.6 11.0 29.5 28.7 15.9 27.3 33.5 32.7 31.6 38.5 21.6 20.3 39.2 33.4 16.2 14.5 25.5 41.8 67.1 15.8 18.3 20.4 23.9 34.2 13.0 19.8 24.4 28.3 26.6 34.6 23.9 13.4 26.5 35.1 39.8 14.0 12.9 10.8 27.0 11.3 29.6 11.5 25.6 24.5 12.0 18.2 18.5 10.0 18.6 27.6 10.3 28.1 49.0 23.7 16.0 22.2 20.2 19.2 12.0 24.0 9.5 21.2 6.5 11.0 8.1 13.1 14.5 10.7 9.4 11.4 13.0 8.0 12.8 11.1 12.0 11.0 7.4 13.0 10.1 11.5 8.6 29.2 37.0 34.4 50.2 30.5 29.2 46.6 28.0 39.7 43.4 UBE3A "ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A" ENSG00000114062 "Ubiquitin protein ligase E3A" Q05086 15 25333728-25439056 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009723, HPA039410, HPA040380" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB009723: AB_639982, HPA039410: AB_10671997, HPA040380: AB_2676952" "unprognostic (7.95e-2)" "unprognostic (2.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.99e-1)" "unprognostic (1.13e-1)" "unprognostic (3.55e-2)" "unprognostic (1.44e-1)" "unprognostic (3.05e-1)" "unprognostic (5.07e-2)" "unprognostic (1.69e-1)" "unprognostic (3.40e-2)" "unprognostic (4.83e-2)" "unprognostic (6.31e-2)" "unprognostic (3.08e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (8.17e-2)" 19.3 19.4 20.3 23.1 25.0 17.8 20.2 30.0 25.1 21.7 19.9 14.3 19.8 14.1 21.0 22.1 19.8 18.5 17.2 24.0 22.2 20.8 20.2 24.6 19.7 23.1 19.1 19.5 23.0 17.2 26.1 24.6 20.1 20.9 20.6 17.9 13.3 19.3 21.5 70.2 18.4 18.8 21.2 19.9 18.8 16.9 26.4 16.4 36.4 25.0 26.6 19.5 19.9 26.6 15.6 11.9 11.6 14.8 21.1 16.0 5.7 19.3 10.9 27.6 16.4 16.1 19.2 13.6 29.8 18.7 21.1 19.2 25.3 9.7 34.7 22.6 22.2 17.9 34.9 21.0 25.8 17.9 11.7 28.8 18.4 14.9 24.2 34.7 21.3 22.6 19.8 19.9 25.5 16.5 29.0 24.8 33.1 10.5 28.7 10.1 17.9 15.9 29.5 41.2 15.3 19.1 30.4 28.3 21.4 24.1 26.2 34.2 21.4 19.6 21.2 37.0 30.6 17.7 21.7 28.4 33.5 46.8 21.2 18.9 19.2 8.6 8.7 11.6 13.3 7.6 15.2 12.0 14.0 15.9 11.9 15.6 16.0 14.2 2.0 21.1 14.8 11.1 10.1 5.7 20.3 25.0 30.0 25.1 22.2 20.8 19.1 19.5 20.9 16.4 UBE3B ENSG00000151148 "Ubiquitin protein ligase E3B" Q7Z3V4 12 109477402-109536705 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041012 Approved Approved "Nuclear speckles,Mitochondria" "Nuclear speckles" Mitochondria "HPA041012: AB_10964435" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.12e-2)" "unprognostic (7.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (4.92e-2)" "unprognostic (7.19e-2)" "unprognostic (2.93e-1)" "unprognostic (4.46e-3)" "unprognostic (9.39e-2)" "unprognostic (1.23e-1)" "prognostic favourable (2.49e-5)" "unprognostic (3.35e-1)" "unprognostic (3.35e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" 14.5 19.3 17.2 12.9 21.2 9.2 15.3 19.7 27.8 14.4 17.3 23.3 14.0 14.6 17.4 16.2 20.1 19.3 13.9 28.6 14.6 11.6 19.8 16.4 15.5 13.1 18.6 13.9 18.4 20.3 25.5 15.1 16.8 15.8 17.5 21.2 20.7 15.7 17.4 34.0 21.6 16.3 18.6 15.2 17.0 17.3 24.5 18.3 18.2 21.1 17.6 15.9 19.5 19.6 15.9 14.5 22.4 16.7 14.3 18.2 11.4 10.4 16.6 13.0 9.4 22.2 17.9 11.4 13.8 15.9 16.8 11.3 17.3 10.8 6.5 10.3 22.6 13.5 13.2 17.7 16.3 14.3 9.3 12.5 10.8 15.6 14.3 10.1 10.5 20.3 16.6 16.3 19.6 18.1 13.6 6.2 19.1 16.4 6.9 14.8 13.3 20.0 11.5 12.3 12.8 14.4 18.9 12.1 22.4 16.1 22.0 10.8 22.4 10.8 16.5 20.9 6.0 10.6 9.8 13.9 11.5 11.5 20.8 8.5 17.3 22.4 15.3 14.3 15.9 16.7 15.7 15.9 15.3 11.2 14.5 12.9 12.9 17.1 19.5 14.3 13.6 13.5 18.2 11.4 17.2 21.2 19.7 27.8 14.6 11.6 18.6 13.9 15.8 18.3 UBE3C "KIAA0010, KIAA10" ENSG00000009335 "Ubiquitin protein ligase E3C" Q15386 7 157138913-157269372 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039915 Approved Approved "Nucleoplasm,Plasma membrane,Mitochondria" Mitochondria "Nucleoplasm, Plasma membrane" "HPA039915: AB_10795264" "unprognostic (2.83e-2)" "unprognostic (9.27e-3)" "unprognostic (2.41e-1)" "unprognostic (2.29e-1)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.02e-2)" "unprognostic (2.34e-2)" "unprognostic (1.58e-1)" "unprognostic (3.01e-3)" "unprognostic (8.64e-2)" "prognostic favourable (9.18e-6)" "unprognostic (9.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-2)" 24.7 21.0 14.0 17.9 23.1 12.4 19.8 25.5 29.9 21.3 23.4 17.2 15.3 17.4 28.8 16.8 26.8 18.8 24.8 31.8 14.4 13.8 21.2 30.5 16.7 16.7 14.5 15.1 20.7 22.1 29.6 20.3 21.3 22.3 19.0 21.0 20.2 31.7 21.5 51.2 21.2 23.9 25.7 16.1 20.5 21.8 35.9 11.1 20.3 15.6 24.5 24.4 23.1 19.1 2.5 4.0 2.1 4.6 3.7 6.6 2.9 22.5 17.9 11.5 23.0 20.7 21.8 12.8 25.0 21.6 21.1 21.4 16.1 18.9 12.2 22.3 27.5 14.4 17.9 23.1 25.2 22.2 16.4 12.4 12.6 11.6 20.7 18.6 18.3 19.3 21.3 23.4 19.5 24.6 18.1 13.7 29.8 19.7 18.2 11.8 18.3 21.7 10.5 13.0 25.1 21.9 24.9 18.5 19.1 24.6 21.2 18.3 10.9 13.1 22.0 26.7 5.7 65.4 31.0 13.7 13.8 12.3 30.6 27.8 30.5 0.5 3.5 2.1 4.8 4.6 6.6 2.5 5.2 5.2 4.0 2.5 4.9 5.9 1.3 3.7 4.5 3.6 5.2 2.9 14.0 23.1 25.5 29.9 14.4 13.8 14.5 15.1 22.3 11.1 UBE3D "C6orf157, DKFZp434A1520, H10BH, UBE2CBP, YJR141W" ENSG00000118420 "Ubiquitin protein ligase E3D" Q7Z6J8 6 82892398-83065841 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027231 Uncertain Approved "Rods & Rings" "Rods & Rings" "HPA027231: AB_2256689" "unprognostic (1.91e-1)" "unprognostic (3.60e-2)" "unprognostic (5.05e-2)" "unprognostic (6.17e-3)" "unprognostic (2.91e-3)" "unprognostic (5.03e-2)" "unprognostic (2.39e-5)" "unprognostic (6.93e-2)" "unprognostic (2.08e-1)" "unprognostic (2.70e-2)" "unprognostic (3.48e-3)" "unprognostic (1.14e-1)" "unprognostic (1.47e-1)" "unprognostic (4.26e-1)" "unprognostic (1.78e-1)" "unprognostic (1.58e-2)" "unprognostic (3.18e-1)" 4.6 9.0 6.3 6.2 9.5 3.0 8.7 13.1 10.6 6.7 5.5 6.0 4.9 7.5 6.9 5.0 6.7 14.0 5.1 5.4 6.1 9.1 7.9 4.9 4.1 7.6 7.4 7.2 8.0 10.1 8.9 11.0 4.2 5.9 4.1 6.8 6.4 6.5 5.6 8.8 4.1 4.2 8.7 5.8 8.2 6.3 3.7 7.7 4.5 10.0 5.2 7.8 8.6 6.0 6.6 3.1 0.3 2.7 1.3 8.2 3.2 2.7 3.8 3.7 3.4 3.1 5.0 3.0 3.0 3.6 3.8 6.5 5.4 1.5 12.5 4.6 1.8 2.9 7.3 3.6 6.0 5.3 16.5 7.2 2.1 5.9 4.2 6.2 3.6 3.9 5.1 4.1 5.0 4.9 10.3 5.7 3.2 3.1 3.8 7.8 4.7 6.1 5.7 8.5 5.0 7.1 3.7 6.7 4.2 1.7 4.3 2.6 2.7 4.5 1.5 1.6 4.4 3.5 7.2 6.3 12.7 4.2 2.8 11.4 3.4 0.0 1.0 0.3 4.7 2.7 6.1 6.6 5.2 3.7 3.1 4.4 5.6 8.2 0.0 1.3 1.2 2.3 5.2 3.2 6.3 9.5 13.1 10.6 6.1 9.1 7.4 7.2 5.9 7.7 UBE4A "E4, KIAA0126, UBOX2, UFD2" ENSG00000110344 "Ubiquitination factor E4A" Q14139 11 118359585-118399211 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055035, HPA064010" Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA055035: , HPA064010: " "unprognostic (1.32e-2)" "unprognostic (8.15e-2)" "unprognostic (5.23e-3)" "unprognostic (3.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.97e-1)" "unprognostic (7.67e-3)" "unprognostic (3.31e-1)" "unprognostic (1.30e-1)" "unprognostic (4.67e-2)" "unprognostic (6.01e-2)" "unprognostic (5.83e-2)" "unprognostic (7.73e-3)" "unprognostic (4.74e-2)" "unprognostic (5.94e-2)" "unprognostic (2.72e-1)" "unprognostic (8.86e-2)" 19.3 18.5 17.7 20.5 30.1 16.6 19.7 49.4 36.6 19.0 18.5 33.0 16.1 20.3 23.2 21.2 21.2 19.8 17.0 20.3 17.7 18.8 20.3 29.5 18.4 22.2 25.7 25.7 24.2 26.7 31.1 24.2 18.6 35.5 21.5 23.1 21.2 20.3 17.2 32.5 25.6 23.7 19.9 25.5 24.0 25.5 21.8 27.5 22.1 22.1 15.1 22.6 21.6 20.4 5.7 11.0 14.6 13.2 7.1 9.0 5.2 9.1 8.9 11.4 11.4 19.8 18.4 11.4 13.6 14.2 10.1 12.4 24.5 22.6 19.3 26.3 17.0 20.3 16.1 12.8 16.8 10.8 7.5 31.6 8.0 12.6 17.1 17.8 24.3 18.5 9.3 20.6 20.3 16.8 17.9 18.2 14.5 17.3 15.2 17.8 10.6 11.4 9.7 16.6 19.7 11.1 21.4 10.4 10.8 19.6 17.0 6.0 22.7 8.2 17.2 15.0 9.9 12.8 11.2 5.4 6.5 18.4 8.3 20.7 15.3 14.6 10.9 10.5 9.0 12.0 6.9 5.7 6.9 6.4 11.0 4.3 7.4 6.6 11.0 7.1 13.2 6.5 7.7 5.2 17.7 30.1 49.4 36.6 17.7 18.8 25.7 25.7 35.5 27.5 UBE4B "E4, KIAA0684, UBOX3, UFD2" ENSG00000130939 "Ubiquitination factor E4B" O95155 1 10032832-10181239 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019219 Approved "HPA019219: AB_1858554" "unprognostic (5.32e-2)" "unprognostic (1.56e-1)" "unprognostic (3.74e-2)" "unprognostic (5.46e-2)" "unprognostic (7.19e-2)" "unprognostic (4.39e-2)" "prognostic unfavourable (3.69e-5)" "unprognostic (2.53e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-1)" "unprognostic (4.26e-1)" "unprognostic (3.10e-1)" "unprognostic (1.86e-3)" "unprognostic (2.99e-1)" "unprognostic (3.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-3)" 11.8 18.6 16.4 11.5 20.2 16.5 12.7 27.1 24.2 17.5 19.3 26.5 12.6 15.1 16.7 12.8 20.4 14.1 11.3 22.5 18.9 17.3 13.0 13.9 10.5 11.3 18.5 15.0 22.8 20.4 24.3 15.3 18.3 23.6 14.5 12.8 18.2 12.0 12.7 43.5 24.3 14.5 16.6 16.3 13.0 15.1 8.6 21.4 15.7 19.7 11.2 13.6 16.8 12.0 6.0 6.7 9.4 7.9 2.9 9.8 5.3 21.6 13.9 17.1 18.8 22.7 30.0 13.5 14.3 18.1 14.0 14.4 15.0 25.4 18.7 17.4 25.4 16.0 21.4 16.5 16.7 19.1 12.0 20.1 24.3 17.6 17.2 21.0 14.3 24.7 15.0 18.9 16.1 20.6 34.5 24.9 13.0 11.3 13.5 10.3 22.8 11.5 13.3 17.0 20.1 14.2 9.9 20.9 16.1 22.5 16.1 29.7 12.3 15.5 17.8 12.6 19.4 15.5 11.6 11.4 15.4 21.6 18.5 24.4 15.9 4.2 7.9 3.6 5.3 6.0 8.8 6.0 8.8 8.5 6.7 5.6 8.0 6.5 9.4 2.9 4.4 3.2 9.8 5.3 16.4 20.2 27.1 24.2 18.9 17.3 18.5 15.0 23.6 21.4 UBLCP1 "CPUB1, MGC10067" ENSG00000164332 "Ubiquitin like domain containing CTD phosphatase 1" Q8WVY7 5 159263081-159286040 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039615 Approved Supported Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA039615: AB_10674425" "unprognostic (1.25e-1)" "unprognostic (3.10e-1)" "unprognostic (6.04e-3)" "unprognostic (3.45e-2)" "unprognostic (7.08e-2)" "unprognostic (6.82e-2)" "prognostic unfavourable (4.46e-5)" "unprognostic (4.01e-1)" "unprognostic (2.14e-2)" "unprognostic (1.98e-1)" "unprognostic (1.91e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (2.51e-2)" 17.1 16.0 16.7 18.4 19.7 16.7 16.3 20.2 33.0 18.5 12.5 12.2 11.4 9.8 22.5 13.1 22.2 14.7 14.5 13.1 20.9 19.1 17.5 14.4 17.8 24.1 19.7 22.7 16.8 12.6 18.0 23.9 19.6 36.7 14.7 14.7 10.9 15.4 17.6 15.3 14.2 13.8 19.5 20.4 22.2 13.3 24.2 15.4 26.8 14.4 16.1 30.1 18.8 16.8 11.9 10.8 21.9 13.9 25.5 19.2 8.2 14.5 10.6 22.0 23.8 22.9 21.2 13.0 15.9 24.2 16.3 21.8 8.6 10.1 13.0 17.6 19.8 11.1 13.6 30.5 28.5 25.9 13.3 10.0 9.3 7.8 28.9 22.6 15.8 18.7 28.7 14.8 29.6 15.5 13.7 17.6 22.7 4.7 12.2 6.9 15.2 6.4 15.5 21.5 15.2 16.1 11.2 11.7 15.5 16.0 10.7 37.4 11.3 15.1 16.5 16.8 14.1 8.7 20.0 14.1 14.2 19.8 17.8 15.6 24.9 21.9 6.5 16.1 16.6 13.5 18.6 11.9 15.8 17.3 8.5 10.9 18.5 19.2 19.4 25.5 13.9 10.8 16.9 8.2 16.7 19.7 20.2 33.0 20.9 19.1 19.7 22.7 36.7 15.4 UBOX5 "KIAA0860, RNF37, Ubce7ip5, UIP5" ENSG00000185019 "U-box domain containing 5" O94941 20 3107573-3160196 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028871 Approved Approved Nucleoplasm Nucleoplasm "HPA028871: AB_10603140" "unprognostic (4.11e-2)" "unprognostic (2.01e-2)" "unprognostic (1.77e-1)" "unprognostic (1.04e-1)" "unprognostic (2.18e-1)" "prognostic favourable (4.52e-5)" "unprognostic (2.58e-2)" "unprognostic (1.02e-1)" "unprognostic (3.11e-2)" "unprognostic (1.61e-1)" "prognostic favourable (1.80e-5)" "unprognostic (4.02e-2)" "unprognostic (9.71e-3)" "unprognostic (3.33e-1)" "unprognostic (5.58e-2)" "unprognostic (1.07e-2)" "unprognostic (1.61e-2)" 10.1 9.9 9.6 10.0 13.0 17.7 15.4 14.9 16.3 11.6 12.7 12.3 9.0 8.6 14.1 8.8 11.2 13.9 8.8 10.8 10.0 9.1 13.7 12.2 10.1 19.6 10.0 10.2 15.2 17.8 12.8 11.6 11.1 11.9 11.8 8.8 9.5 13.2 13.6 34.1 16.3 10.7 12.2 7.9 10.4 10.8 15.1 9.3 14.9 10.4 11.1 11.5 12.8 9.7 8.7 7.0 11.4 7.0 7.5 8.4 5.5 6.2 6.4 5.1 3.3 6.7 3.7 2.7 5.3 4.8 6.4 6.4 6.0 5.4 4.7 2.0 4.4 8.7 3.4 7.9 3.9 1.4 2.9 8.2 1.9 5.5 5.4 3.4 3.3 4.8 5.9 5.2 6.5 4.1 6.7 4.7 3.7 4.2 7.0 5.2 4.0 3.9 4.7 6.4 3.4 4.0 6.4 6.3 6.0 3.3 19.6 4.1 8.4 2.6 4.6 4.3 2.8 4.7 4.3 6.2 9.1 4.2 2.4 3.6 3.1 11.1 7.0 11.4 7.1 7.0 7.3 8.7 8.0 5.8 7.0 6.8 8.4 8.1 11.4 7.5 5.9 5.6 7.6 5.5 9.6 13.0 14.9 16.3 10.0 9.1 10.0 10.2 11.9 9.3 UBR1 ENSG00000159459 "Ubiquitin protein ligase E3 component n-recognin 1" Q8IWV7 15 42942897-43106113 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038838 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA038838: AB_10673120" "unprognostic (1.07e-2)" "unprognostic (5.02e-2)" "unprognostic (9.77e-2)" "unprognostic (1.55e-2)" "unprognostic (1.89e-2)" "unprognostic (1.29e-1)" "unprognostic (2.67e-1)" "unprognostic (1.49e-1)" "unprognostic (4.79e-1)" "unprognostic (2.97e-2)" "unprognostic (1.93e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-3)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" 16.7 13.2 13.7 18.3 16.7 28.4 18.8 21.8 18.1 18.2 16.2 14.8 10.5 11.3 21.0 12.9 10.8 15.9 14.2 19.7 10.0 15.4 14.4 10.6 16.6 14.9 11.8 10.5 16.3 16.4 26.3 25.6 16.2 18.9 15.3 12.9 12.5 11.8 16.8 23.6 11.0 14.4 18.2 12.1 14.7 13.8 13.7 14.7 23.2 18.8 9.7 14.3 17.3 19.7 4.6 5.0 5.5 4.2 6.2 7.2 1.8 4.9 7.2 8.3 6.7 13.2 10.2 7.9 12.1 13.4 10.7 13.9 9.1 3.9 5.8 7.2 12.4 8.6 11.9 10.6 12.8 11.9 5.8 22.9 14.4 4.4 9.2 16.1 11.0 11.0 6.0 13.1 10.7 12.0 13.0 8.8 13.3 2.8 8.7 4.8 4.7 7.4 11.4 11.4 5.0 10.8 11.7 8.4 7.5 15.9 8.4 5.6 8.1 8.4 16.5 13.2 8.2 11.7 12.2 10.4 17.6 16.7 9.0 10.2 11.9 4.4 3.0 5.2 5.7 4.2 6.5 4.1 5.9 6.9 2.9 4.6 5.9 7.2 5.5 6.2 3.4 5.0 4.1 1.8 13.7 16.7 21.8 18.1 10.0 15.4 11.8 10.5 18.9 14.7 UBR2 "bA49A4.1, C6orf133, dJ392M17.3, KIAA0349" ENSG00000024048 "Ubiquitin protein ligase E3 component n-recognin 2" Q8IWV8 6 42564062-42693504 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 25.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 25.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027869, HPA027880" Approved Approved "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA027869: AB_10600416, HPA027880: AB_10601217" "unprognostic (3.26e-1)" "unprognostic (1.29e-1)" "unprognostic (8.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.08e-2)" "unprognostic (4.23e-2)" "unprognostic (1.32e-1)" "unprognostic (7.24e-2)" "unprognostic (5.05e-2)" "prognostic favourable (1.65e-4)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (1.30e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-1)" "unprognostic (5.78e-2)" "unprognostic (7.77e-3)" 19.8 18.8 14.4 21.8 16.7 22.1 18.6 26.6 20.4 17.2 19.3 17.8 17.8 20.1 29.5 16.8 16.2 15.6 16.2 16.8 13.8 13.2 17.8 24.0 19.3 18.0 16.7 12.9 20.8 24.6 28.0 26.3 16.3 17.2 16.5 20.1 15.8 18.3 15.6 33.5 18.0 24.6 19.9 15.9 21.3 18.2 9.2 17.2 26.1 20.1 14.9 17.7 18.9 29.8 3.6 3.5 25.2 5.7 3.9 4.4 1.9 15.7 8.0 9.3 14.6 19.2 18.5 12.6 12.2 13.2 10.8 11.3 11.5 6.5 10.9 9.7 13.1 16.0 13.4 10.4 13.8 14.6 9.4 17.2 11.9 14.9 15.6 16.6 11.9 13.0 11.4 10.7 11.8 12.2 20.1 13.8 10.4 12.8 13.0 14.7 8.5 7.8 11.6 13.9 16.2 12.4 13.8 11.1 8.8 12.3 11.9 11.9 11.6 16.1 17.6 9.9 7.7 12.0 8.8 12.8 11.3 16.8 5.2 12.5 6.0 10.4 4.6 9.2 4.4 4.8 3.7 3.4 2.9 3.4 3.5 3.6 3.0 3.3 25.2 3.9 5.7 2.6 3.3 1.9 14.4 16.7 26.6 20.4 13.8 13.2 16.7 12.9 17.2 17.2 UBR3 "DKFZp434P117, FLJ37422, KIAA2024, ZNF650" ENSG00000144357 "Ubiquitin protein ligase E3 component n-recognin 3 (putative)" Q6ZT12 2 169827458-170084131 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035390 Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA035390: AB_10670699" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.19e-2)" "unprognostic (5.56e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.18e-1)" 11.9 15.5 10.9 6.1 18.3 5.4 9.6 15.5 18.9 9.9 10.0 9.8 9.1 6.7 11.5 7.1 10.7 8.1 7.8 23.1 10.3 7.2 12.9 16.9 9.2 5.6 11.9 14.0 8.9 9.8 20.9 14.9 7.2 14.7 11.2 7.3 8.0 11.1 9.2 76.3 11.5 8.4 9.6 10.2 6.9 9.2 7.9 11.4 6.3 14.9 10.9 6.0 12.8 8.7 2.0 2.8 1.9 2.1 2.4 4.3 1.2 8.8 7.5 8.0 10.6 16.0 12.7 6.8 16.0 9.3 9.3 7.5 11.5 5.6 10.0 13.9 12.4 11.7 9.5 8.1 11.6 10.4 8.2 36.6 8.0 12.2 8.0 12.1 11.9 7.6 7.6 12.1 8.1 9.1 19.0 10.9 15.7 8.3 7.8 5.9 6.3 6.3 7.5 13.2 10.6 6.7 12.5 15.8 8.6 11.2 10.4 6.5 6.8 6.8 11.5 14.0 5.7 10.9 10.0 8.9 6.9 9.2 11.5 7.1 7.7 0.0 2.1 1.7 3.2 1.8 4.2 2.0 1.9 2.7 2.8 1.2 3.3 4.3 1.9 2.4 1.6 2.4 3.1 1.2 10.9 18.3 15.5 18.6 10.3 7.2 11.9 14.0 14.7 11.4 UBR4 "KIAA0462, KIAA1307, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074506-19210276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" 24.4 25.4 22.4 29.0 25.4 58.3 23.7 28.5 32.5 22.4 28.5 26.3 31.5 18.2 34.0 32.5 22.7 20.3 27.3 20.5 23.3 15.9 25.5 29.7 31.2 20.3 21.0 20.9 35.5 21.0 40.9 31.4 28.4 25.0 30.7 20.5 30.6 24.7 27.1 55.9 69.0 25.5 39.3 20.2 26.5 30.2 41.1 21.6 37.7 26.1 17.3 25.9 43.4 29.0 4.6 9.1 18.3 18.5 2.7 3.4 4.6 22.9 23.2 21.0 15.5 39.3 20.3 18.2 17.9 18.9 19.5 17.8 37.0 19.8 13.9 16.8 23.6 15.7 16.4 17.8 18.3 11.5 14.5 31.7 22.4 24.1 27.7 19.4 21.1 18.1 22.9 39.7 38.3 21.3 21.6 12.9 18.5 16.4 9.1 23.7 17.0 13.1 12.8 16.4 11.6 17.6 13.5 14.9 14.8 21.2 12.2 15.2 8.4 15.3 33.0 22.9 14.3 27.1 20.0 15.3 9.2 16.1 15.7 30.0 19.4 18.3 18.5 2.9 3.4 3.8 2.9 4.6 3.0 1.9 9.1 2.9 2.7 2.5 9.8 2.7 1.3 4.3 2.1 4.6 22.4 25.4 28.5 32.5 23.3 15.9 21.0 20.9 25.0 21.6 UBR5 "DD5, EDD, EDD1, HYD, KIAA0896" ENSG00000104517 "Ubiquitin protein ligase E3 component n-recognin 5" O95071 8 102253012-102412841 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053688 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA053688: " "unprognostic (3.79e-3)" "unprognostic (7.44e-3)" "unprognostic (1.25e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-2)" "unprognostic (1.41e-1)" "prognostic unfavourable (1.26e-4)" "unprognostic (2.50e-1)" "unprognostic (1.75e-2)" "unprognostic (7.54e-3)" "unprognostic (8.29e-3)" "unprognostic (3.84e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.69e-2)" "unprognostic (2.45e-1)" 27.0 16.7 27.1 29.5 31.7 30.3 29.2 40.8 32.8 24.9 25.0 19.1 21.1 14.4 26.8 24.0 23.8 22.0 17.6 22.7 25.5 15.3 17.9 17.0 24.2 29.6 21.9 20.6 29.7 22.2 32.4 25.5 25.0 23.6 20.2 17.1 19.7 22.9 21.8 39.9 29.7 22.4 29.3 17.5 21.9 21.1 39.7 28.3 37.9 20.3 15.9 27.0 27.5 28.6 5.0 4.0 6.3 5.5 2.4 7.1 2.1 23.2 10.4 20.2 10.3 19.9 20.3 18.6 17.6 15.6 13.8 12.1 10.4 15.7 46.4 15.2 16.5 14.2 17.2 15.3 19.4 20.0 8.4 38.7 14.2 18.7 17.7 12.0 21.4 23.2 15.3 14.2 24.8 16.5 18.6 26.4 13.5 21.0 30.5 14.4 15.2 11.8 17.8 11.9 22.0 12.6 22.9 14.9 12.4 12.3 12.0 12.2 19.2 12.8 16.5 14.7 17.2 13.2 12.2 14.1 13.6 47.7 14.6 18.8 11.9 3.1 3.4 5.0 5.6 3.4 5.6 5.0 6.0 5.9 4.0 3.9 4.8 7.1 6.3 2.4 5.5 3.6 7.1 2.1 27.1 31.7 40.8 32.8 25.5 15.3 21.9 20.6 23.6 28.3 UBR7 C14orf130 ENSG00000012963 "Ubiquitin protein ligase E3 component n-recognin 7 (putative)" Q8N806 14 93207056-93229215 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000861 Approved Approved Nucleoplasm Nucleoplasm "HPA000861: AB_1078321" "unprognostic (9.60e-2)" "unprognostic (5.12e-3)" "unprognostic (1.11e-1)" "unprognostic (9.20e-2)" "unprognostic (3.30e-1)" "unprognostic (2.12e-1)" "prognostic unfavourable (8.12e-5)" "unprognostic (1.14e-1)" "unprognostic (9.83e-2)" "unprognostic (1.04e-2)" "unprognostic (4.30e-2)" "unprognostic (5.94e-2)" "prognostic favourable (9.76e-5)" "unprognostic (3.61e-2)" "unprognostic (2.91e-1)" "unprognostic (2.86e-1)" "unprognostic (1.78e-1)" 14.1 12.3 16.4 12.5 22.9 17.0 17.5 20.0 25.8 17.1 15.7 17.7 11.3 11.1 14.9 13.4 14.8 13.7 11.9 19.0 14.2 12.8 15.3 13.2 11.9 18.0 14.0 17.1 17.0 20.4 28.2 11.5 11.4 13.3 13.9 17.1 13.6 13.7 14.9 19.9 15.2 12.7 14.1 16.9 13.8 14.1 21.1 14.3 31.9 15.4 12.9 23.3 13.4 13.3 18.1 10.7 15.8 9.5 11.5 16.5 8.2 6.4 8.7 13.3 11.1 6.3 6.7 4.7 13.7 9.7 15.2 11.6 6.3 7.4 15.4 11.5 6.9 7.8 14.3 7.7 15.7 11.9 7.7 11.1 9.3 6.0 2.9 16.2 12.5 4.0 5.4 8.4 5.3 8.5 10.3 15.5 14.5 18.9 26.3 8.9 6.1 15.7 20.3 23.9 8.4 5.1 10.6 16.8 12.0 9.8 8.2 4.0 14.9 11.2 6.5 11.2 6.1 9.6 14.1 17.9 27.4 15.8 9.8 12.6 9.5 15.8 7.3 11.8 12.7 9.1 13.3 18.1 11.4 11.7 7.8 14.8 10.0 10.6 11.5 11.5 9.5 10.7 16.5 8.2 16.4 22.9 20.0 25.8 14.2 12.8 14.0 17.1 13.3 14.3 UCHL1 "PARK5, PGP9.5, Uch-L1" ENSG00000154277 "Ubiquitin C-terminal hydrolase L1" P09936 4 41256413-41268455 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 225.8" "Cell line enhanced" "Detected in many" "EFO-21: 97.1;SCLC-21H: 96.9;U-251 MG: 88.7;U-266/84: 85.5;U-87 MG: 94.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 3.6" "Lineage enriched" "Detected in single" 37 "B-cells: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002580, HPA005993, CAB079024" Enhanced Supported Supported Nucleoplasm,Cytosol 440000 Cytosol Nucleoplasm "CAB002580: AB_563981, CAB079024: , HPA005993: AB_1858560" "unprognostic (1.54e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-1)" "prognostic unfavourable (4.08e-5)" "unprognostic (2.34e-1)" "unprognostic (1.98e-1)" "unprognostic (6.28e-3)" "unprognostic (1.09e-2)" "unprognostic (4.31e-2)" "unprognostic (8.77e-3)" "unprognostic (3.56e-3)" "unprognostic (3.70e-2)" "unprognostic (1.82e-3)" "unprognostic (1.24e-2)" "unprognostic (7.12e-3)" "unprognostic (2.10e-2)" "prognostic unfavourable (1.93e-4)" 8.2 40.2 52.4 8.9 65.1 2.0 3.1 17.5 225.8 4.5 6.3 11.5 0.0 5.5 6.0 1.8 2.7 5.7 6.5 5.4 53.4 97.4 14.0 2.0 2.7 6.5 62.0 57.1 15.4 6.3 1.8 30.5 2.7 100.6 5.3 4.7 6.0 3.0 4.4 7.5 2.7 8.6 5.2 38.6 2.3 2.8 8.0 8.3 0.0 3.9 0.0 4.5 5.6 2.8 3.6 0.0 0.0 0.0 0.0 0.0 0.6 0.2 55.0 11.4 0.0 1.5 1.9 0.0 57.6 29.7 20.4 20.6 11.1 0.0 0.0 97.1 29.3 0.1 21.0 0.0 8.3 0.1 8.6 0.0 0.3 0.0 44.0 0.0 0.0 10.6 0.2 16.3 0.0 0.1 0.0 0.2 10.8 0.0 0.0 0.9 32.9 62.2 0.0 24.4 0.0 30.8 0.0 96.9 60.9 0.3 0.2 0.1 0.0 0.4 0.3 1.3 0.4 0.0 88.7 45.5 85.5 0.2 94.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 52.4 65.1 17.5 92.6 53.4 97.4 62.0 57.1 100.6 8.3 UCHL3 ENSG00000118939 "Ubiquitin C-terminal hydrolase L3" P15374 13 75549480-75606020 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019678, CAB037139, CAB037208" Approved Supported Nucleoplasm,Cytosol 490000 "Nucleoplasm, Cytosol" "CAB037139: AB_1841234, CAB037208: AB_1841235, HPA019678: AB_1858583" "unprognostic (4.16e-1)" "unprognostic (3.84e-2)" "unprognostic (8.83e-3)" "unprognostic (1.14e-1)" "unprognostic (5.15e-2)" "unprognostic (6.46e-3)" "prognostic unfavourable (6.41e-4)" "unprognostic (1.19e-1)" "unprognostic (5.59e-2)" "unprognostic (9.71e-2)" "unprognostic (1.24e-1)" "unprognostic (7.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.97e-1)" "unprognostic (2.76e-2)" "unprognostic (8.84e-2)" "unprognostic (3.26e-2)" 13.7 39.1 23.6 11.9 37.6 17.4 21.4 17.5 18.7 10.6 21.2 11.4 12.8 12.8 9.0 40.5 37.7 8.1 12.4 15.5 20.6 12.6 20.7 36.8 10.3 12.2 18.2 13.5 7.7 20.8 9.5 28.9 26.3 14.7 12.4 25.0 6.1 24.0 14.9 31.7 28.8 15.0 16.9 13.3 15.3 14.5 24.6 18.6 18.9 28.1 29.8 20.2 16.0 16.2 17.4 46.0 15.8 43.5 20.5 23.4 17.3 53.2 8.9 7.8 5.4 14.6 17.4 22.5 20.2 20.0 26.3 29.5 49.3 25.9 27.6 14.6 21.2 29.4 18.2 49.0 40.0 14.7 15.9 17.4 14.8 31.5 21.1 41.5 13.1 15.5 34.1 20.5 33.1 25.6 19.0 7.9 39.5 19.2 16.8 27.2 11.6 26.9 13.5 12.6 18.1 30.9 21.7 23.5 6.9 11.5 22.4 9.3 12.9 11.8 19.8 11.5 13.7 12.2 26.9 11.1 12.3 32.1 23.2 45.0 8.2 15.6 24.1 15.8 10.9 43.5 14.2 17.4 19.9 15.5 33.6 16.0 19.8 18.3 5.4 20.5 36.2 46.0 23.4 17.3 23.6 37.6 17.5 18.7 20.6 12.6 18.2 13.5 14.7 18.6 UCHL5 "CGI-70, INO80R, UCH37" ENSG00000116750 "Ubiquitin C-terminal hydrolase L5" Q9Y5K5 1 193012250-193060080 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005908, HPA075383" Approved Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA005908: AB_1858585, HPA075383: " "unprognostic (3.66e-2)" "unprognostic (3.84e-3)" "unprognostic (5.17e-2)" "unprognostic (5.98e-2)" "unprognostic (1.20e-2)" "unprognostic (1.20e-1)" "unprognostic (3.50e-2)" "unprognostic (7.41e-2)" "unprognostic (1.96e-2)" "unprognostic (1.04e-3)" "unprognostic (3.44e-3)" "unprognostic (6.92e-2)" "unprognostic (6.41e-3)" "unprognostic (1.51e-1)" "unprognostic (7.15e-2)" "prognostic unfavourable (7.10e-5)" "unprognostic (4.33e-2)" 15.7 18.3 20.1 16.1 26.2 16.0 18.2 30.1 34.8 10.9 17.7 11.5 12.6 19.0 12.5 14.7 26.1 10.7 11.9 22.0 21.6 20.6 21.6 28.3 12.4 19.9 21.3 29.4 13.4 24.8 15.6 16.2 17.8 33.3 17.8 18.8 10.3 19.3 12.9 29.1 16.7 18.0 13.9 20.1 17.3 14.0 9.9 17.5 20.0 15.1 19.1 23.0 14.8 14.8 22.5 20.8 23.8 21.1 35.6 30.9 20.9 33.2 18.5 16.0 16.4 9.3 9.5 19.1 19.6 10.0 18.8 16.3 17.4 22.6 26.1 18.9 10.8 20.7 21.3 25.3 24.9 26.9 15.3 30.9 23.9 23.1 15.0 48.5 17.4 8.7 11.3 26.9 23.9 18.5 67.7 21.3 15.9 26.8 35.7 18.0 14.8 11.7 20.7 18.0 50.7 17.5 19.5 16.3 20.1 17.6 25.5 27.2 20.7 24.5 12.0 17.6 5.4 17.8 31.1 16.6 25.6 29.4 10.5 30.3 29.9 23.8 16.5 19.0 28.3 19.5 30.9 22.5 25.9 26.9 19.4 18.0 28.2 30.5 10.0 35.6 21.1 20.8 24.8 20.9 20.1 26.2 30.1 34.8 21.6 20.6 21.3 29.4 33.3 17.5 UCK1 "FLJ12255, URK1" ENSG00000130717 "Uridine-cytidine kinase 1" Q9HA47 9 131523801-131531268 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050969 Approved Approved Nucleoplasm Nucleoplasm "HPA050969: " "unprognostic (2.20e-1)" "prognostic favourable (3.19e-4)" "unprognostic (1.16e-2)" "unprognostic (1.74e-3)" "unprognostic (7.29e-2)" "unprognostic (1.43e-1)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.54e-1)" "prognostic favourable (2.21e-7)" "unprognostic (5.11e-2)" "unprognostic (3.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.07e-1)" 13.2 15.9 21.7 13.7 22.5 13.7 15.6 29.9 23.2 15.0 15.6 17.3 20.8 11.4 12.2 19.3 14.5 17.6 16.5 21.0 19.6 18.4 18.3 26.7 12.7 12.9 20.4 19.1 21.3 24.0 17.6 14.4 16.4 14.8 14.9 9.2 17.6 24.1 18.3 30.0 12.0 12.2 14.8 19.9 12.1 13.4 15.7 15.6 12.5 18.5 10.8 11.5 13.6 9.4 7.9 6.6 9.4 7.8 6.8 13.5 6.1 6.9 15.4 17.9 22.9 12.7 9.1 15.2 11.3 16.8 19.6 15.0 15.3 6.4 7.6 6.8 13.5 13.6 16.6 14.5 8.5 13.9 15.5 7.1 23.2 9.6 18.2 11.6 10.5 10.2 13.6 15.8 11.5 12.0 8.9 5.8 14.4 27.7 15.8 5.9 21.2 15.4 15.2 27.7 12.7 12.6 6.6 24.2 15.2 16.3 12.5 17.6 24.4 6.9 8.8 21.8 11.1 13.5 11.0 12.0 15.3 9.6 10.8 8.1 15.1 2.3 6.2 9.4 8.5 7.8 11.3 7.9 10.1 7.6 5.7 7.9 13.5 6.8 4.1 6.8 2.7 6.6 12.3 6.1 21.7 22.5 29.9 23.2 19.6 18.4 20.4 19.1 14.8 15.6 UCK2 UMPK ENSG00000143179 "Uridine-cytidine kinase 2" Q9BZX2 1 165827531-165911618 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 65.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057128 Approved Nucleoplasm Nucleoplasm "HPA057128: " "unprognostic (5.37e-2)" "unprognostic (1.75e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-2)" "unprognostic (4.54e-2)" "unprognostic (6.83e-3)" "prognostic unfavourable (9.22e-8)" "prognostic unfavourable (4.98e-4)" "prognostic unfavourable (6.70e-4)" "unprognostic (3.04e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-2)" "prognostic unfavourable (5.12e-13)" "unprognostic (2.49e-3)" "unprognostic (1.14e-1)" "unprognostic (2.01e-3)" "unprognostic (1.83e-1)" 12.5 7.1 6.5 11.1 8.6 11.6 17.5 16.9 9.6 9.3 18.4 8.9 11.0 15.3 10.1 15.3 20.5 8.8 9.0 9.6 6.4 6.6 6.6 14.6 11.1 10.3 10.5 6.6 7.5 17.6 7.9 9.4 65.8 11.2 8.1 19.9 5.0 16.1 9.9 20.9 15.0 24.8 10.0 8.2 7.7 13.2 7.2 7.9 13.1 6.4 12.4 12.3 9.0 11.1 3.4 14.7 0.8 5.6 3.4 3.9 2.0 25.2 26.3 14.2 12.7 7.3 12.2 23.1 27.9 20.6 29.8 34.0 25.0 27.8 12.5 19.9 17.3 20.8 26.6 32.8 26.7 22.9 22.5 14.5 22.6 25.6 18.2 28.3 11.1 11.5 16.9 56.2 35.1 19.6 38.3 18.0 26.7 18.3 25.1 18.2 38.9 25.5 11.5 15.6 42.5 13.8 16.5 21.4 25.3 19.9 39.4 19.3 24.3 27.0 20.4 16.7 23.3 18.9 29.5 24.2 36.0 46.3 14.4 18.8 12.7 0.8 5.6 0.1 1.8 3.7 3.9 3.4 1.7 2.4 14.7 3.4 0.0 1.4 0.2 3.4 3.2 14.0 2.2 2.0 6.5 8.6 16.9 9.6 6.4 6.6 10.5 6.6 11.2 7.9 UCKL1 "FLJ20517, URKL1" ENSG00000198276 "Uridine-cytidine kinase 1 like 1" Q9NWZ5 20 63939829-63956415 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004722, HPA004769" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA004722: AB_1080455, HPA004769: AB_1080453" "unprognostic (1.03e-1)" "unprognostic (2.77e-2)" "unprognostic (2.64e-1)" "unprognostic (8.34e-2)" "unprognostic (7.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.45e-1)" "unprognostic (1.29e-1)" "prognostic favourable (4.42e-4)" "unprognostic (5.87e-2)" "unprognostic (3.18e-2)" "unprognostic (9.11e-2)" "unprognostic (2.81e-1)" "unprognostic (3.01e-1)" "unprognostic (5.26e-3)" 17.4 18.1 16.5 16.0 18.3 21.1 19.8 50.4 20.7 18.5 21.9 21.6 17.3 32.0 18.0 17.7 19.7 17.9 12.0 21.0 17.1 9.4 21.3 20.6 15.6 18.3 20.3 11.5 31.7 22.6 14.1 22.1 17.5 15.7 19.4 9.1 31.0 28.9 24.4 52.3 27.9 29.8 18.1 11.8 26.7 20.1 11.5 19.7 16.7 24.1 33.1 20.1 16.2 21.2 22.2 8.9 6.3 14.0 5.3 14.8 7.9 11.3 12.1 10.4 13.9 7.7 6.6 16.8 9.1 6.3 19.0 9.5 28.9 8.9 11.5 15.5 5.9 18.7 8.1 12.6 3.8 4.8 13.6 8.7 24.2 42.2 8.5 14.8 16.7 9.2 11.3 7.6 6.3 8.7 12.3 12.3 5.9 14.6 17.4 25.9 7.7 28.4 17.8 7.8 19.8 7.8 16.5 24.8 14.5 13.2 13.0 14.0 13.6 13.5 9.6 20.2 7.6 13.1 11.8 12.9 6.9 5.3 10.3 10.7 7.6 4.2 7.7 6.3 13.2 12.9 14.8 22.2 12.8 11.2 8.9 12.7 7.5 9.0 1.2 5.3 14.0 5.1 13.5 7.9 16.5 18.3 50.4 20.7 17.1 9.4 20.3 11.5 15.7 19.7 UFSP1 UFSP ENSG00000176125 "UFM1 specific peptidase 1 (inactive)" Q6NVU6 7 100888723-100889718 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA027099 Uncertain "HPA027099: AB_2214069" "unprognostic (8.56e-2)" "unprognostic (2.62e-2)" "unprognostic (2.23e-1)" "unprognostic (1.94e-1)" "unprognostic (7.21e-3)" "unprognostic (1.18e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (2.11e-1)" "unprognostic (3.55e-3)" "unprognostic (5.71e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-1)" "unprognostic (2.48e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-2)" 7.4 6.3 2.8 3.9 5.4 2.6 4.0 3.1 4.1 3.1 4.5 6.1 2.8 4.3 5.6 6.1 4.1 4.6 2.5 3.6 4.8 4.6 5.3 6.5 2.8 5.9 8.9 4.1 5.8 8.6 3.4 6.8 5.7 3.9 4.8 2.8 3.0 6.4 5.0 10.6 3.4 5.8 4.0 3.5 4.3 5.1 2.0 7.8 6.5 4.2 2.8 5.0 4.8 4.7 5.9 7.2 2.4 3.9 4.4 6.4 3.1 3.6 4.7 1.1 4.8 4.8 2.8 3.0 2.8 0.9 1.2 0.8 1.9 2.6 0.8 2.2 2.2 7.0 1.4 1.7 0.7 3.2 10.5 3.0 3.8 2.2 4.7 1.3 1.5 3.2 2.1 1.5 6.0 0.3 4.5 2.3 1.8 9.0 3.0 7.4 3.6 6.5 1.5 1.4 6.9 2.1 1.5 3.4 5.5 5.5 7.2 3.0 1.7 1.1 1.2 3.2 3.2 3.4 2.2 2.3 2.7 0.2 1.1 2.3 3.6 0.0 3.9 2.4 5.4 3.4 6.1 1.8 4.7 2.9 4.8 5.9 5.3 6.4 0.8 4.4 3.3 7.2 2.0 3.1 2.8 5.4 3.1 4.1 4.8 4.6 8.9 4.1 3.9 7.8 UFSP2 "C4orf20, FLJ11200" ENSG00000109775 "UFM1 specific peptidase 2" Q9NUQ7 4 185399540-185425985 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039985, HPA043298" Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA039985: AB_10794206, HPA043298: AB_10795037" "unprognostic (8.87e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-1)" "unprognostic (1.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (3.63e-2)" "unprognostic (3.19e-2)" "unprognostic (3.69e-1)" "unprognostic (1.50e-1)" "unprognostic (2.04e-2)" "unprognostic (2.56e-1)" "prognostic favourable (1.07e-8)" "unprognostic (1.92e-1)" "unprognostic (8.12e-2)" "unprognostic (9.36e-3)" "unprognostic (6.70e-3)" 15.8 20.3 12.5 10.3 14.9 4.1 18.7 11.3 20.3 17.3 17.4 16.3 17.0 11.0 19.4 17.4 20.1 17.3 13.5 24.2 11.4 11.7 28.1 19.2 13.2 11.6 14.6 11.3 30.5 20.1 18.3 22.8 12.3 17.0 18.4 12.6 13.7 14.4 20.3 40.8 16.6 13.6 16.9 20.2 14.2 17.3 23.7 14.6 15.8 23.5 19.2 12.2 20.8 13.3 15.6 13.0 5.5 7.9 13.9 17.9 8.2 12.0 7.4 20.8 15.0 18.8 19.6 11.5 12.5 12.7 15.0 14.2 12.4 15.5 12.2 5.8 15.1 9.6 16.1 20.3 15.6 13.0 9.4 6.4 7.2 11.2 20.8 9.7 8.0 11.5 15.9 13.1 13.6 24.0 16.3 24.6 19.4 7.3 13.0 7.3 5.4 10.7 12.9 8.2 14.6 14.4 7.0 12.4 11.6 7.8 12.7 15.2 9.8 6.9 13.9 6.3 11.1 4.3 9.7 22.4 8.6 5.8 20.3 6.1 15.9 5.5 7.9 5.4 16.3 6.8 17.1 15.6 16.5 17.6 9.8 11.0 17.8 17.9 0.4 13.9 6.6 13.0 14.0 8.2 12.5 14.9 11.3 20.3 11.4 11.7 14.6 11.3 17.0 14.6 UGCG GCS ENSG00000148154 "UDP-glucose ceramide glucosyltransferase" Q16739 9 111896766-111935369 "Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "LHCN-M2: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 19 "plasmacytoid DC: 39.7" "Lineage enriched" "Detected in many" 19 "dendritic cells: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024124 Approved "HPA024124: AB_1858595" "unprognostic (1.22e-2)" "prognostic favourable (6.62e-4)" "unprognostic (5.39e-2)" "prognostic favourable (4.44e-5)" "unprognostic (1.53e-2)" "unprognostic (9.70e-2)" "unprognostic (3.20e-2)" "unprognostic (2.04e-1)" "unprognostic (3.40e-1)" "unprognostic (1.31e-1)" "unprognostic (1.95e-2)" "unprognostic (3.22e-1)" "unprognostic (9.84e-3)" "unprognostic (2.24e-2)" "unprognostic (4.92e-2)" "unprognostic (1.99e-1)" "unprognostic (3.77e-2)" 33.7 37.7 5.9 21.4 7.8 55.2 20.5 9.5 11.2 14.6 19.6 5.0 3.3 13.3 10.6 8.6 34.0 11.1 24.5 17.5 8.6 9.0 23.8 18.4 28.1 35.4 7.1 5.8 15.9 11.4 3.5 11.9 15.3 6.8 12.4 10.5 11.9 10.8 5.4 14.0 21.7 25.5 12.4 12.9 33.1 26.1 11.7 6.2 17.9 8.5 16.9 27.7 34.2 25.9 2.0 39.7 0.4 0.3 0.5 1.2 0.5 24.1 2.6 4.2 2.8 9.2 11.1 2.2 15.1 16.0 17.8 24.1 5.1 18.6 5.7 12.0 10.0 12.4 4.9 6.5 19.1 2.3 2.8 2.3 3.9 2.5 6.6 2.5 3.7 11.0 5.1 16.9 24.4 5.4 12.6 11.1 52.4 4.1 2.7 2.8 4.8 2.7 3.2 30.2 1.8 40.9 9.2 2.0 3.2 6.7 5.7 16.6 30.5 2.6 25.5 8.2 4.2 22.9 10.8 2.1 7.6 2.6 10.1 1.6 11.1 0.0 0.1 0.0 0.4 0.2 0.7 1.6 0.8 0.6 0.6 2.0 0.7 0.7 0.4 0.5 0.3 39.7 1.2 0.5 5.9 7.8 9.5 11.2 8.6 9.0 7.1 5.8 6.8 6.2 UGDH ENSG00000109814 "UDP-glucose 6-dehydrogenase" O60701 4 39498755-39528311 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 125.8" "Cell line enhanced" "Detected in all" "A549: 84.2;Hep G2: 97.5;U-2197: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034444, HPA036656, HPA036657" Enhanced Supported Nucleoplasm 42000 Nucleoplasm "CAB034444: AB_2019602, HPA036656: AB_10671706, HPA036657: AB_10672360" "unprognostic (1.22e-2)" "unprognostic (1.62e-1)" "unprognostic (2.73e-2)" "unprognostic (3.96e-2)" "unprognostic (5.54e-2)" "unprognostic (1.63e-1)" "unprognostic (8.78e-3)" "unprognostic (6.07e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-1)" "unprognostic (9.81e-3)" "unprognostic (6.86e-2)" "prognostic unfavourable (5.51e-10)" "unprognostic (2.48e-1)" "unprognostic (2.04e-1)" "unprognostic (1.66e-1)" "unprognostic (4.97e-2)" 25.9 11.3 4.4 24.7 3.2 0.2 12.7 4.0 3.1 13.0 29.3 3.8 10.2 13.7 11.5 9.7 22.9 9.9 12.9 10.1 3.6 3.5 28.2 125.8 13.5 4.7 4.0 2.2 20.6 24.9 5.1 4.7 26.8 5.3 13.2 23.3 7.5 8.2 7.3 7.5 5.5 24.2 17.7 3.7 3.3 14.1 5.0 3.8 1.7 16.7 12.7 7.1 30.2 24.1 12.0 12.3 17.1 12.0 21.8 22.4 10.2 4.8 84.2 9.3 12.1 30.4 33.8 7.8 16.0 19.1 15.9 14.6 11.8 18.2 3.1 10.1 22.2 5.0 9.6 4.5 16.7 3.9 1.7 3.4 10.9 97.5 12.0 4.2 3.5 11.3 2.5 27.1 8.5 10.1 4.5 2.6 10.9 14.3 4.1 4.6 7.5 6.2 7.1 14.4 3.1 8.7 19.3 4.7 6.9 9.9 5.8 6.7 3.2 3.5 11.8 16.3 7.6 60.6 7.6 5.9 4.3 3.1 13.7 3.6 8.5 17.1 12.0 10.9 14.3 10.6 22.4 10.9 11.4 14.8 10.7 12.0 9.8 12.0 2.3 21.8 6.1 12.3 7.3 10.2 4.4 3.2 4.0 3.0 3.6 3.5 4.0 2.2 5.3 3.8 UGP2 "UGP1, UGPP1" ENSG00000169764 "UDP-glucose pyrophosphorylase 2" Q16851 2 63840940-63891562 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 185.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 93.6;T-reg: 29.9" "Group enriched" "Detected in all" 5 "granulocytes: 93.6;T-cells: 29.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034696, HPA034697, HPA064836" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria 12000000 "Centrosome, Mitochondria" Nucleoplasm "HPA034696: AB_10670171, HPA034697: AB_2674287, HPA064836: AB_2685365" "unprognostic (1.00e-2)" "unprognostic (6.93e-2)" "unprognostic (5.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-2)" "unprognostic (1.91e-1)" "prognostic favourable (2.50e-5)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-2)" "unprognostic (8.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (3.93e-2)" "unprognostic (3.81e-1)" "unprognostic (8.44e-2)" 58.2 14.7 23.3 13.6 22.5 7.8 25.2 12.4 30.4 13.3 38.2 6.7 7.4 12.3 15.5 12.5 19.8 12.7 12.2 46.3 18.8 13.2 33.0 185.5 12.7 15.2 17.3 18.3 12.0 13.4 17.1 22.9 31.0 19.3 11.0 33.1 5.7 18.5 12.9 104.1 11.0 17.2 16.8 8.6 9.9 13.0 8.1 10.5 31.0 17.4 75.5 12.7 19.7 19.5 6.4 5.9 93.6 7.8 12.7 29.9 11.0 27.3 14.4 13.8 9.3 47.2 61.2 58.0 35.4 29.0 19.1 22.8 36.9 23.3 28.7 10.7 38.0 12.0 16.7 22.2 31.0 19.2 7.1 18.2 10.2 25.2 22.5 16.0 16.1 40.1 40.7 17.9 18.5 26.5 9.1 11.7 79.6 10.8 21.7 15.1 33.1 10.1 17.8 27.4 16.6 33.8 16.0 7.3 6.0 28.3 36.4 13.4 10.4 11.4 36.1 20.0 31.6 29.7 18.6 20.9 9.4 36.4 24.0 25.1 61.0 93.6 7.0 9.7 9.9 7.8 10.3 6.4 11.4 10.3 5.9 6.2 12.6 11.2 9.0 12.7 7.6 5.5 29.9 11.0 23.3 22.5 12.4 30.4 18.8 13.2 17.3 18.3 19.3 10.5 UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 111.7;liver: 50.1;urinary bladder: 32.7" "Cell line enhanced" "Detected in some" "CACO-2: 13.4;EFO-21: 20.8;HaCaT: 74.4;RT4: 37.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009819, HPA054065" Enhanced "CAB009819: AB_2241481, HPA054065: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavourable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.8 0.5 0.2 0.5 2.0 0.3 0.9 13.0 0.0 1.1 0.1 0.1 0.0 111.7 50.1 1.9 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.3 0.1 3.3 0.4 0.1 1.3 1.2 0.1 3.8 1.2 2.3 0.1 0.1 8.1 0.2 0.1 0.5 0.2 5.6 8.7 32.7 2.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.4 0.0 20.8 0.0 74.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 37.6 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" Q9Y4X1 4 69588417-69653249 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 10.6;liver: 14.5;pituitary gland: 21.2" "Cell line enhanced" "Detected in some" "ASC diff: 3.1;HUVEC TERT2: 1.9;U-266/70: 3.5" "Cancer enhanced" "Detected in some" "liver cancer: 0.7" "Region enriched" "Detected in single" 17 "pons and medulla: 1.7" "Cell type enhanced" "Detected in some" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "HPA017261, HPA045108" Uncertain "HPA017261: AB_10963582, HPA045108: " "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 14.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.7 0.0 0.0 1.5 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.5 2.0 0.5 0.9 0.4 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.2 1.7 0.5 0.4 0.2 0.2 0.1 0.1 0.4 0.2 0.1 0.3 0.2 0.1 2.0 0.9 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 UGT2A2 ENSG00000271271 "UDP glucuronosyltransferase family 2 member A2" Q9Y4X1 4 69589309-69639642 "Enzymes, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "cervix, uterine: 1.6;kidney: 2.6;liver: 5.4;pituitary gland: 3.8;skin 1: 1.8" "Cell line enhanced" "Detected in single" "U-266/70: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain "HPA045108: " 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.4 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951791 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 150.5;kidney: 43.2" "Cell line enriched" "Detected in some" 9 "Hep G2: 20.5" "Cancer enriched" "Detected in many" 5 "renal cancer: 46.9" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 10 "eosinophil: 5.3" "Lineage enriched" "Detected in single" 53 "granulocytes: 5.3" HPA045108 Supported "HPA045108: " "prognostic favourable (3.31e-4)" "unprognostic (3.97e-3)" "unprognostic (8.87e-3)" "prognostic favourable (6.07e-7)" "unprognostic (2.10e-2)" 0.1 0.1 0.1 4.3 0.1 0.0 0.7 0.1 0.1 0.1 63.8 0.1 0.1 31.9 0.1 1.7 0.1 0.1 14.6 0.3 0.1 0.1 43.2 9.6 0.1 0.1 0.1 0.1 0.1 12.0 0.0 0.1 0.1 0.1 0.1 8.6 0.1 0.1 0.1 0.1 0.1 150.5 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 UGT2B10 ENSG00000109181 "UDP glucuronosyltransferase family 2 member B10" P36537 4 68815993-68831196 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 277 "liver: 120.4" "Cell line enriched" "Detected in single" 39 "Hep G2: 15.8" "Cancer enriched" "Detected in single" 296 "liver cancer: 93.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain "HPA045108: " "unprognostic (3.50e-3)" "unprognostic (1.92e-3)" "unprognostic (4.17e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 120.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B11 ENSG00000213759 "UDP glucuronosyltransferase family 2 member B11" O75310 4 69199951-69214731 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "breast: 77.4" "Cell line enhanced" "Detected in some" "Hep G2: 1.5;HL-60: 3.0;NB-4: 2.4;RPTEC TERT1: 3.6;U-2197: 1.4" "Group enriched" "Detected in some" 17 "breast cancer: 17.4;liver cancer: 13.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "basophil: 6.8;eosinophil: 5.6" "Lineage enriched" "Detected in single" 68 "granulocytes: 6.8" HPA045108 Uncertain "HPA045108: " "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.49e-1)" "unprognostic (6.53e-2)" "unprognostic (2.26e-2)" "unprognostic (1.65e-1)" "unprognostic (7.84e-3)" "unprognostic (5.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.51e-3)" 0.1 0.0 0.1 0.1 0.1 0.0 77.4 0.1 0.1 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.0 3.3 0.1 0.1 0.0 1.2 7.3 0.1 0.1 0.1 0.1 0.1 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 7.0 0.1 0.1 1.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.9 0.1 0.1 0.1 0.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 3.6 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.6 0.0 0.0 6.8 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UGT2B15 UGT2B8 ENSG00000196620 "UDP glucuronosyltransferase family 2 member B15" P54855 4 68646630-68670628 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "gallbladder: 22.4;intestine: 50.7;liver: 65.4" "Cell line enhanced" "Detected in some" "A549: 3.2;HL-60: 2.1;RH-30: 1.2;RPMI-8226: 1.1" "Cancer enriched" "Detected in many" 10 "liver cancer: 120.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 2.7" "Lineage enhanced" "Detected in single" "B-cells: 2.7" HPA045108 Approved "HPA045108: " "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (2.22e-2)" "unprognostic (3.86e-1)" "unprognostic (1.94e-1)" "prognostic favourable (9.82e-4)" "unprognostic (6.73e-2)" "unprognostic (3.49e-2)" "unprognostic (7.84e-2)" "unprognostic (5.81e-3)" "unprognostic (2.39e-2)" "unprognostic (5.38e-2)" "prognostic favourable (4.50e-4)" 0.1 0.0 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.1 48.0 0.1 0.1 5.4 0.1 0.1 0.2 0.0 22.4 0.1 0.1 0.0 0.1 65.4 0.1 0.1 0.1 0.1 0.1 5.3 0.0 0.1 0.1 0.1 0.2 1.6 0.1 0.1 0.1 0.1 0.0 50.7 0.1 0.1 0.1 5.7 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 2.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 1.1 0.0 0.2 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.2 0.4 0.1 0.5 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UGT2B17 ENSG00000197888 "UDP glucuronosyltransferase family 2 member B17" O75795 4 68537184-68568527 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 68.1;liver: 21.6" "Group enriched" "Detected in some" 7 "BEWO: 3.1;NB-4: 3.5;RPMI-8226: 5.1;SH-SY5Y: 2.3;U-2197: 2.1" "Group enriched" "Detected in many" 7 "colorectal cancer: 16.3;liver cancer: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 38 "memory B-cell: 3.3;naive B-cell: 11.9" "Lineage enriched" "Detected in single" 59 "B-cells: 11.9" HPA045108 Supported "HPA045108: " "unprognostic (1.66e-1)" "unprognostic (2.97e-2)" "unprognostic (2.96e-2)" "unprognostic (2.41e-1)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.36e-1)" "unprognostic (8.44e-3)" "unprognostic (9.67e-2)" "unprognostic (4.80e-3)" "unprognostic (8.52e-2)" "unprognostic (2.45e-1)" "unprognostic (6.44e-2)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" 0.4 0.1 0.4 4.7 0.4 0.0 0.4 0.4 0.4 0.4 55.6 0.4 0.4 54.1 0.4 0.4 0.4 0.1 0.4 0.4 0.4 0.1 0.4 21.6 0.4 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 20.7 0.4 0.4 0.4 0.4 0.1 68.1 1.1 0.4 0.4 0.1 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 11.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.4 0.4 0.4 0.1 0.4 0.4 0.4 0.4 UGT2B28 ENSG00000135226 "UDP glucuronosyltransferase family 2 member B28" Q9BY64 4 69280499-69295050 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "breast: 71.7;salivary gland: 25.6" "Group enriched" "Detected in some" 10 "Daudi: 6.9;NB-4: 6.3" "Cancer enriched" "Detected in single" 8 "breast cancer: 1.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "basophil: 2.5;eosinophil: 4.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 4.0" HPA045108 Uncertain "Intracellular and membrane" "HPA045108: " "unprognostic (1.81e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-3)" "unprognostic (1.51e-2)" "unprognostic (4.37e-5)" "unprognostic (9.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 71.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 25.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 0.2 4.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 105 "liver: 175.1" "Cell line enriched" "Detected in some" 9 "RH-30: 10.1" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" "CAB033260: AB_2241496, HPA045108: " "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.1 175.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 125.4;liver: 156.0" "Group enriched" "Detected in some" 5 "EFO-21: 20.5;RPTEC TERT1: 81.6" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain "HPA045108: " "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favourable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favourable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favourable (5.38e-4)" 0.1 0.1 0.1 0.2 0.1 0.0 0.4 0.1 0.1 3.1 7.9 0.1 2.5 6.4 0.6 4.7 0.1 4.7 1.5 0.1 0.1 0.1 125.4 156.0 0.2 0.1 0.1 0.1 0.6 14.7 0.0 0.1 0.2 0.1 0.3 0.4 0.2 1.0 2.7 0.3 0.2 27.7 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 81.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 UGT3A1 FLJ34658 ENSG00000145626 "UDP glycosyltransferase family 3 member A1" Q6NUS8 5 35951010-36001028 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "kidney: 44.0;liver: 47.7" "Cell line enriched" "Detected in single" 42 "RH-30: 24.7" "Group enriched" "Detected in some" 15 "liver cancer: 6.7;renal cancer: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047697, HPA056290" Uncertain Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA047697: , HPA056290: " "unprognostic (2.41e-3)" "unprognostic (4.47e-1)" "unprognostic (4.04e-1)" "unprognostic (4.62e-1)" "unprognostic (1.42e-2)" "unprognostic (6.05e-2)" "unprognostic (9.14e-2)" "unprognostic (1.76e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 5.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 44.0 47.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.1 0.0 3.2 0.1 6.1 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.4 0.2 0.2 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035017-36071358 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 37.0;skin 1: 14.4;testis: 13.2" "Cell line enhanced" "Detected in some" "HDLM-2: 5.2;MOLT-4: 9.3;REH: 21.8;T-47d: 5.7;THP-1: 12.9" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Region enhanced" "Detected in single" "pons and medulla: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: " "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" 0.1 1.1 0.1 0.0 0.2 6.4 1.6 0.1 0.6 0.1 0.1 0.5 0.4 0.0 0.1 0.8 0.1 0.1 0.2 0.2 0.1 0.6 5.6 0.8 0.1 0.0 0.5 0.0 0.2 0.0 0.0 1.7 0.2 2.0 0.6 0.0 2.9 0.1 0.0 0.1 14.4 0.1 0.0 0.3 1.4 0.1 13.2 0.0 37.0 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.4 5.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 4.0 0.0 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.6 0.1 0.6 0.5 0.0 2.0 0.0 UGT8 CGT ENSG00000174607 "UDP glycosyltransferase 8" Q16880 4 114598455-114678224 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 96.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.3;RH-30: 12.1;RPTEC TERT1: 25.0;SCLC-21H: 14.2;U-87 MG: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 7.3;naive B-cell: 10.6" "Lineage enriched" "Detected in single" 12 "B-cells: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014405, HPA065785" Enhanced Approved Mitochondria Mitochondria "HPA014405: AB_1858606, HPA065785: " "unprognostic (7.38e-3)" "unprognostic (2.07e-1)" "unprognostic (1.25e-2)" "unprognostic (2.38e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "unprognostic (7.78e-2)" "unprognostic (1.56e-3)" "unprognostic (4.49e-2)" "unprognostic (2.76e-1)" "prognostic favourable (8.55e-5)" "unprognostic (2.80e-1)" "unprognostic (1.78e-2)" "unprognostic (7.53e-2)" "unprognostic (1.49e-1)" 0.9 0.8 13.2 2.8 30.0 1.0 3.1 2.7 44.8 4.9 15.5 66.6 0.0 18.4 2.7 0.6 1.2 3.0 7.1 0.9 24.2 12.4 20.1 0.8 1.0 3.2 53.9 15.9 0.8 4.8 0.3 0.9 0.5 38.3 0.9 17.3 0.0 4.5 0.8 0.8 1.8 16.1 1.5 96.6 1.3 10.0 3.3 42.6 0.0 8.5 0.0 3.4 0.8 1.0 10.6 0.0 0.9 0.0 0.0 0.6 0.3 0.3 0.1 2.0 0.3 0.1 0.0 0.3 0.1 0.0 0.0 1.5 6.8 25.3 7.6 0.6 0.1 10.7 0.0 0.0 0.0 0.1 5.3 0.1 11.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 6.4 1.5 0.0 0.1 0.1 0.8 3.0 3.8 0.7 12.1 0.2 25.0 0.3 14.2 2.1 0.1 2.2 0.3 0.4 2.4 0.5 0.5 8.6 0.3 7.9 2.5 0.4 0.2 12.5 0.4 7.8 0.2 0.0 0.9 0.0 0.0 0.6 7.3 0.1 0.0 0.0 10.6 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.3 13.2 30.0 2.7 24.4 24.2 12.4 53.9 15.9 38.3 42.6 UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529629 "Enzymes, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071190 Approved "Nucleoplasm,Golgi apparatus,Midbody" "Nucleoplasm, Golgi apparatus" Midbody "HPA071190: " "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-2)" "unprognostic (8.16e-2)" "unprognostic (9.63e-2)" "unprognostic (1.82e-1)" "unprognostic (7.81e-3)" "unprognostic (9.10e-2)" "unprognostic (3.11e-1)" "unprognostic (3.44e-2)" "unprognostic (9.08e-2)" "unprognostic (8.77e-2)" "unprognostic (4.66e-2)" 21.6 22.0 23.5 18.9 26.2 30.1 23.5 10.8 30.5 14.3 16.3 17.2 30.8 16.3 11.5 12.9 16.0 12.9 12.1 11.4 27.0 31.8 27.9 32.4 16.9 24.3 30.6 20.3 12.1 11.8 25.0 12.5 16.5 33.4 14.7 17.4 14.1 15.9 22.9 30.6 11.5 21.8 9.6 20.5 21.3 16.8 10.4 14.1 23.0 17.1 11.7 24.1 16.1 12.8 5.7 4.3 4.5 9.2 5.9 8.5 4.0 20.8 9.8 5.1 12.5 14.7 11.6 11.6 27.7 15.1 22.7 16.3 6.3 13.1 17.1 24.2 20.6 12.1 9.8 15.2 36.6 23.4 7.1 16.9 12.2 5.7 11.3 24.6 19.8 11.9 16.2 22.3 21.4 13.0 14.7 23.8 38.9 8.8 13.0 6.5 6.8 13.3 8.4 22.9 14.2 15.1 21.6 9.3 8.6 24.4 22.7 17.8 19.6 27.6 20.2 26.0 14.7 17.9 38.5 24.7 34.2 20.2 21.6 12.1 23.4 4.5 3.3 3.7 8.2 8.6 8.5 5.4 6.2 6.8 3.6 5.7 6.3 7.1 2.0 5.9 9.2 4.3 4.9 4.0 23.5 26.2 10.8 30.5 27.0 31.8 30.6 20.3 33.4 14.1 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 75.6" "Cell line enhanced" "Detected in many" "MOLT-4: 62.6;REH: 142.1" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 8.2" "Group enriched" "Detected in many" 4 "dendritic cells: 8.2;T-cells: 4.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavourable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavourable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavourable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 0.7 0.0 0.7 8.2 3.7 16.5 0.7 0.3 4.2 0.3 1.5 1.6 0.0 2.1 0.3 0.2 2.0 0.0 1.0 0.9 1.2 0.1 0.1 0.3 10.0 4.3 0.7 0.3 0.6 0.0 0.0 1.0 1.4 0.0 1.4 0.0 0.0 0.0 0.3 1.9 2.2 0.8 0.7 2.2 1.9 3.1 4.0 75.6 0.0 4.0 6.6 1.1 0.0 0.4 8.2 1.5 0.4 0.9 4.2 0.9 15.6 11.3 17.2 12.2 0.5 2.0 2.7 12.7 6.1 13.3 12.9 13.5 7.9 8.9 3.1 5.6 7.8 11.8 6.9 9.4 14.4 13.4 7.7 10.6 14.4 0.2 18.9 11.7 0.9 0.5 7.2 1.8 3.9 11.0 10.3 7.9 12.2 62.6 11.6 7.7 12.3 142.1 38.3 6.5 3.6 11.5 12.7 10.1 10.0 5.5 1.7 9.9 18.1 4.9 14.1 11.5 18.2 15.3 4.4 4.5 26.2 8.1 18.4 17.9 0.6 0.4 0.2 1.1 0.1 0.1 0.3 1.5 1.9 2.2 0.4 0.4 1.5 1.5 0.9 0.3 8.2 4.2 0.9 UHRF2 "MGC33463, NIRF, RNF107, TDRD23, URF2" ENSG00000147854 "Ubiquitin like with PHD and ring finger domains 2" Q96PU4 9 6413151-6507054 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026633, HPA026697" Enhanced Nucleoplasm Nucleoplasm "HPA026633: AB_1858610, HPA026697: AB_1858611" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (8.40e-2)" "unprognostic (4.35e-3)" "unprognostic (4.12e-2)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "unprognostic (5.69e-3)" "unprognostic (2.14e-2)" "unprognostic (6.21e-2)" "unprognostic (8.77e-2)" "unprognostic (7.42e-2)" "unprognostic (1.50e-1)" 14.1 12.9 10.6 25.4 12.2 49.1 19.0 24.8 11.8 18.6 15.6 12.7 17.6 7.9 17.5 15.1 13.3 12.0 11.9 11.3 10.2 10.6 10.1 9.8 13.5 19.3 12.3 10.5 18.9 14.5 12.7 12.7 14.6 11.4 19.3 12.0 10.7 13.0 16.4 15.7 11.0 12.0 17.1 12.2 14.1 11.6 10.6 14.8 40.3 15.2 10.2 19.8 18.7 18.2 5.1 2.5 7.5 1.4 1.2 3.6 1.2 6.6 7.5 10.9 4.6 9.0 12.9 8.0 15.3 9.4 9.6 16.9 4.8 4.8 10.2 3.3 7.6 4.3 10.0 8.9 14.8 18.3 4.7 17.7 14.7 7.6 7.4 8.2 6.0 5.8 5.8 7.5 18.4 37.5 1.7 9.9 22.7 2.3 13.8 32.1 4.2 5.6 15.8 5.0 3.6 7.2 4.6 9.9 3.8 6.6 4.4 9.6 5.5 16.6 31.7 10.3 3.8 4.3 12.8 2.6 7.9 11.9 5.0 7.2 4.1 7.5 1.1 4.3 2.3 0.9 1.7 3.5 3.6 1.8 0.7 5.1 2.3 3.0 1.3 1.2 1.4 2.5 3.5 1.2 10.6 12.2 24.8 11.8 10.2 10.6 12.3 10.5 11.4 14.8 ULK1 "ATG1, ATG1A" ENSG00000177169 "Unc-51 like autophagy activating kinase 1" O75385 12 131894651-131923167 "Enzymes, Plasma proteins, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 6.9;plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063990 Approved Cytosol Cytosol "HPA063990: " "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (2.52e-3)" "unprognostic (2.21e-3)" "unprognostic (8.01e-3)" "unprognostic (5.48e-2)" "unprognostic (2.74e-2)" "unprognostic (5.04e-3)" "unprognostic (3.94e-3)" "unprognostic (2.03e-2)" "unprognostic (9.09e-3)" "unprognostic (8.19e-2)" "unprognostic (6.25e-2)" "unprognostic (2.38e-1)" "unprognostic (2.75e-1)" "unprognostic (1.82e-2)" "unprognostic (3.16e-1)" 10.9 18.6 14.6 9.2 49.6 33.2 8.9 24.0 24.4 14.4 11.8 6.9 13.3 11.7 16.5 10.7 9.8 10.6 16.2 17.4 11.5 8.3 9.0 15.8 9.0 8.3 7.9 12.0 18.2 59.6 13.8 23.8 17.2 11.6 13.4 4.0 13.9 18.1 13.4 33.4 24.3 11.5 10.2 5.4 16.5 11.4 11.4 11.4 13.8 10.7 9.6 6.5 12.1 10.9 0.6 6.4 6.9 1.7 0.2 0.8 0.6 5.1 16.6 7.7 9.6 3.5 2.8 10.5 8.2 5.9 3.5 2.8 3.6 5.3 1.4 8.6 5.7 5.1 1.7 3.2 1.0 5.5 10.0 3.4 13.6 4.8 6.5 2.5 7.6 5.2 9.0 3.9 1.6 4.3 4.5 4.1 2.3 11.7 15.3 14.5 8.5 15.9 11.6 2.8 6.8 2.0 6.4 19.6 10.8 8.7 9.0 4.5 13.7 16.8 8.2 8.4 5.0 14.6 3.7 18.3 6.6 1.8 14.2 4.3 9.6 0.2 1.7 2.3 0.8 0.7 0.2 0.1 0.7 0.7 0.3 0.6 0.5 0.5 6.9 0.2 0.7 6.4 0.5 0.6 14.6 49.6 24.0 24.4 11.5 8.3 7.9 12.0 11.6 11.4 ULK2 "ATG1B, KIAA0623, Unc51.2" ENSG00000083290 "Unc-51 like autophagy activating kinase 2" Q8IYT8 17 19770829-19867936 "Enzymes, Predicted intracellular proteins" "Autophagy, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 6.9;non-classical monocyte: 5.8" "Lineage enriched" "Detected in many" 4 "monocytes: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037021 Approved "CAB037021: AB_1841237" "unprognostic (1.47e-1)" "unprognostic (1.88e-1)" "unprognostic (2.56e-1)" "unprognostic (1.03e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-1)" "unprognostic (6.53e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.11e-3)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-1)" "unprognostic (1.38e-2)" 10.3 7.1 15.5 4.4 19.1 2.8 7.6 15.5 21.8 9.3 7.2 28.3 6.7 3.1 9.5 8.4 6.8 11.5 7.7 8.3 15.0 10.9 7.0 3.7 8.8 4.6 15.8 12.0 12.4 7.5 14.2 4.2 8.5 15.9 9.0 4.8 8.5 5.3 11.0 13.5 7.8 3.6 9.9 28.3 7.1 5.5 33.0 14.6 2.0 7.0 1.4 3.8 7.7 6.3 0.1 1.4 0.5 6.9 0.4 1.6 0.6 8.6 8.9 12.8 1.8 7.5 14.2 0.0 7.2 8.9 7.5 7.1 0.1 1.8 0.0 3.8 9.2 4.1 0.0 1.4 7.1 7.1 9.3 0.2 3.8 0.0 9.8 0.0 4.4 9.2 11.2 3.8 3.2 5.2 0.0 0.0 6.3 2.4 0.0 0.4 1.9 2.3 0.5 0.0 0.0 5.4 3.8 3.2 13.3 11.3 1.4 4.0 8.8 3.3 8.3 0.0 1.1 2.8 4.3 0.0 0.0 0.0 1.1 0.0 2.6 0.0 1.5 0.3 0.6 6.9 0.2 0.1 1.0 1.0 1.4 0.1 1.6 1.0 0.5 0.4 5.8 0.1 0.2 0.6 15.5 19.1 15.5 21.8 15.0 10.9 15.8 12.0 15.9 14.6 ULK3 "DKFZP434C131, FLJ90566" ENSG00000140474 "Unc-51 like kinase 3" Q6PHR2 15 74836116-74843346 "Enzymes, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040474 Approved "HPA040474: " "unprognostic (3.67e-2)" "unprognostic (8.90e-3)" "unprognostic (2.65e-3)" "unprognostic (1.59e-2)" "unprognostic (1.70e-1)" "unprognostic (2.07e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (1.47e-2)" "unprognostic (4.18e-2)" "prognostic favourable (7.47e-4)" "unprognostic (1.97e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-2)" "unprognostic (1.63e-1)" "unprognostic (1.16e-1)" "unprognostic (4.97e-3)" 7.0 11.7 11.8 8.4 15.4 2.9 7.4 21.3 20.4 7.9 13.8 9.0 9.0 7.9 5.3 9.5 33.9 6.7 9.6 14.1 11.8 8.9 13.4 9.3 6.4 7.9 11.2 15.3 4.9 14.7 12.1 12.3 5.7 21.1 8.2 14.4 10.4 10.4 7.4 19.1 24.6 20.3 7.2 5.8 9.9 11.1 6.0 7.6 4.2 6.1 10.9 13.7 8.6 10.6 3.8 4.2 3.8 7.8 5.8 12.6 4.9 3.8 10.5 5.5 9.5 6.3 4.1 3.6 3.1 4.5 6.4 7.0 4.1 8.8 8.3 5.9 3.4 3.9 15.4 4.3 2.7 16.0 15.2 24.9 13.5 5.0 9.2 5.9 15.9 5.5 8.5 5.6 5.3 9.7 6.9 9.1 5.2 5.8 4.3 6.1 6.2 5.4 12.8 6.7 15.9 4.1 4.9 10.3 13.0 6.0 5.7 19.0 8.3 14.9 5.4 8.6 5.5 8.4 6.6 12.6 11.4 6.1 4.8 17.4 7.4 3.8 3.6 1.4 12.6 7.8 10.1 3.8 7.4 10.3 4.0 3.5 8.1 5.5 0.9 5.8 6.2 4.2 9.7 4.9 11.8 15.4 21.3 20.4 11.8 8.9 11.2 15.3 21.1 7.6 ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962430 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" 4.3 4.8 5.1 4.7 8.3 10.3 4.2 4.3 5.4 11.9 2.8 5.9 6.0 2.1 10.7 10.9 2.8 12.3 3.1 13.1 5.2 3.0 5.4 3.4 5.5 4.2 3.1 4.2 4.5 3.6 13.5 19.7 9.0 5.8 4.4 2.8 6.7 4.2 4.5 1.4 3.5 3.3 5.1 5.7 4.4 3.4 27.5 3.4 6.3 7.1 1.7 8.4 4.0 6.0 6.4 5.1 10.7 6.3 2.6 10.3 5.2 7.2 1.7 2.6 3.0 1.1 1.7 4.5 2.5 2.6 3.0 2.6 0.9 2.1 8.4 1.4 5.7 3.7 3.2 1.9 2.8 1.1 0.9 1.6 5.3 2.8 3.9 5.5 1.7 1.6 2.2 14.7 3.0 2.1 1.8 7.0 2.2 5.8 6.9 4.4 3.2 3.0 1.5 8.4 3.7 6.4 7.0 1.3 9.7 2.5 1.2 2.0 2.9 1.8 6.1 1.9 2.2 13.0 2.0 4.2 7.9 3.5 10.8 5.8 2.3 5.7 5.8 5.8 8.0 6.3 6.5 5.6 8.6 7.2 5.1 6.4 6.5 9.2 10.7 2.6 3.2 4.6 10.3 5.2 5.1 8.3 4.3 5.4 5.2 3.0 3.1 4.2 5.8 3.4 UMPS ENSG00000114491 "Uridine monophosphate synthetase" P11172 3 124730366-124749273 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Decarboxylase, Glycosyltransferase, Lyase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036178, HPA036179" Uncertain Supported Cytosol Cytosol "HPA036178: AB_10673002, HPA036179: AB_10673615" "unprognostic (6.41e-2)" "unprognostic (6.70e-2)" "unprognostic (1.79e-2)" "unprognostic (1.13e-3)" "unprognostic (2.70e-1)" "unprognostic (1.72e-1)" "unprognostic (1.15e-3)" "unprognostic (5.51e-2)" "unprognostic (4.85e-3)" "unprognostic (1.43e-1)" "unprognostic (5.36e-2)" "prognostic unfavourable (9.20e-4)" "unprognostic (2.18e-2)" "unprognostic (1.58e-2)" "unprognostic (1.91e-1)" "unprognostic (4.61e-2)" "unprognostic (1.31e-1)" 8.4 12.2 4.9 6.8 6.8 4.8 8.0 9.3 7.6 5.9 9.1 8.5 5.2 8.4 6.8 6.7 13.2 8.2 6.6 3.6 4.0 3.9 9.6 20.7 5.2 10.1 7.3 3.6 8.9 19.0 9.5 9.3 11.6 4.7 6.4 7.1 6.4 8.9 4.0 10.9 9.5 8.5 5.5 5.9 9.8 8.3 6.8 6.2 10.6 7.4 12.0 9.3 7.8 6.4 16.6 13.1 4.6 9.8 10.2 13.0 7.9 1.4 4.3 5.0 2.0 3.0 3.4 5.2 7.4 2.3 3.1 2.6 3.7 2.0 3.8 8.2 2.9 8.3 7.0 2.4 5.0 4.3 4.0 7.7 2.8 2.6 2.6 8.0 5.9 3.8 2.3 1.9 3.9 1.4 3.5 1.8 2.3 3.3 9.9 1.5 10.9 2.8 6.5 5.9 3.1 2.5 2.4 4.0 2.6 11.1 4.0 4.1 4.0 3.0 14.2 2.5 5.0 6.8 2.9 7.4 10.1 10.3 2.8 3.3 2.5 4.5 9.0 4.6 12.5 9.8 12.1 13.7 8.9 11.3 13.1 16.6 13.0 10.4 0.6 10.2 8.0 9.7 10.3 7.9 4.9 6.8 9.3 5.7 4.0 3.9 7.3 3.6 4.7 6.2 UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097574-109110992 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB011605 Uncertain Approved Cytosol Cytosol "CAB011605: AB_778737" "unprognostic (4.38e-2)" "unprognostic (3.82e-3)" "unprognostic (1.03e-2)" "unprognostic (1.33e-2)" "unprognostic (4.64e-1)" "unprognostic (4.10e-2)" "prognostic unfavourable (6.40e-4)" "unprognostic (5.68e-3)" "prognostic unfavourable (3.06e-4)" "unprognostic (4.66e-2)" "unprognostic (8.78e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.57e-2)" "unprognostic (4.50e-1)" "unprognostic (1.40e-2)" "unprognostic (6.89e-2)" 16.3 44.1 17.0 19.4 17.0 10.0 22.8 10.5 14.4 13.5 20.3 10.2 21.4 12.6 11.8 10.8 22.5 11.8 11.0 15.4 13.5 13.1 20.4 23.3 7.1 12.1 19.6 12.2 12.3 12.7 17.3 8.9 18.6 12.0 12.9 22.1 10.7 16.6 19.7 29.1 22.5 13.5 11.0 19.7 13.2 12.3 35.6 9.8 35.1 25.1 19.8 19.0 11.5 14.4 9.8 3.9 5.8 3.0 8.7 19.5 7.9 20.0 20.6 19.8 18.0 33.1 9.5 19.0 11.9 8.1 18.8 14.4 16.3 13.8 26.3 17.9 10.6 12.7 21.9 12.3 18.3 22.3 40.7 25.7 11.9 27.6 4.9 38.2 15.9 8.5 11.3 9.0 5.0 13.5 20.8 8.8 12.6 25.0 35.1 45.1 35.3 31.8 32.3 29.9 22.4 11.7 25.3 28.3 15.7 21.3 18.4 10.3 34.2 17.9 6.9 16.3 14.6 10.7 16.4 17.2 37.0 50.0 12.4 25.7 19.8 5.8 1.5 2.7 13.4 3.0 19.5 9.8 15.9 15.5 3.9 9.2 10.3 11.5 0.0 8.7 3.0 2.8 14.0 7.9 17.0 17.0 10.5 14.4 13.5 13.1 19.6 12.2 12.0 9.8 UPB1 BUP1 ENSG00000100024 "Beta-ureidopropionase 1" Q9UBR1 22 24494107-24528390 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 85.7" "Group enriched" "Detected in some" 5 "CACO-2: 10.9;NB-4: 4.5;THP-1: 6.0;U-937: 6.8" "Cancer enriched" "Detected in some" 8 "liver cancer: 25.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "basophil: 11.4;neutrophil: 3.0" "Lineage enriched" "Detected in single" 43 "granulocytes: 11.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA000728 Enhanced 790000 "HPA000728: AB_1080471" "unprognostic (7.27e-2)" "unprognostic (4.57e-3)" "unprognostic (2.27e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (1.09e-4)" "prognostic favourable (2.30e-7)" "unprognostic (8.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.93e-1)" "unprognostic (4.89e-6)" "unprognostic (3.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (1.99e-1)" "unprognostic (4.63e-3)" 0.1 0.0 0.1 0.1 0.2 1.0 0.1 0.1 0.1 0.1 1.1 0.1 0.1 0.6 0.1 0.5 0.1 0.0 0.1 0.5 0.1 0.0 13.5 85.7 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.2 0.2 1.5 0.1 0.1 0.2 0.0 0.8 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 11.4 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 10.9 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 1.2 0.0 0.3 1.1 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.4 0.3 0.1 0.0 0.2 1.1 1.3 0.3 0.0 0.0 6.0 0.5 0.1 0.1 0.0 0.0 1.1 0.0 1.3 1.3 6.8 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 3.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108733 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "hTERT-HME1: 102.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA054040: , HPA055394: AB_2682805" "unprognostic (1.16e-1)" "prognostic unfavourable (1.02e-4)" "unprognostic (5.96e-2)" "unprognostic (1.01e-1)" "unprognostic (3.21e-3)" "unprognostic (6.36e-2)" "unprognostic (1.78e-3)" "prognostic unfavourable (1.97e-4)" "unprognostic (3.81e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (1.52e-3)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" 16.7 8.4 2.8 12.6 4.2 17.6 7.1 5.7 3.8 10.3 8.0 1.7 2.1 7.5 2.8 4.2 37.7 3.3 8.5 7.0 2.3 3.3 12.4 9.1 18.3 17.4 5.8 1.4 2.9 5.8 2.4 5.0 28.9 5.5 3.0 7.6 2.9 7.5 2.1 5.1 2.0 9.7 5.2 3.9 13.9 2.5 1.8 4.8 1.2 6.2 34.0 19.4 7.9 19.6 0.6 8.2 15.7 22.0 5.7 19.7 16.0 6.5 7.8 0.8 1.6 2.6 1.2 8.0 3.2 4.4 4.1 5.1 3.2 3.1 0.0 1.1 2.6 4.5 1.5 13.0 2.6 1.3 1.4 0.2 1.8 1.3 2.4 0.2 0.5 1.6 6.3 1.8 102.5 2.6 0.4 3.8 2.1 0.7 0.0 1.1 3.1 6.8 0.0 1.7 1.7 9.4 3.3 0.7 0.7 3.3 0.9 23.7 0.8 0.2 3.7 9.6 8.2 2.6 8.1 7.4 9.9 1.1 9.7 0.9 23.2 15.7 22.0 15.1 19.7 16.7 12.5 0.2 12.6 13.5 8.2 0.6 13.0 12.0 9.1 5.7 15.9 0.7 11.2 16.0 2.8 4.2 5.7 3.8 2.3 3.3 5.8 1.4 5.5 4.8 UPP2 "UDRPASE2, UP2, UPASE2" ENSG00000007001 "Uridine phosphorylase 2" O95045 2 157876702-158136154 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 40.1;liver: 22.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.0;REH: 1.5" "Cancer enriched" "Detected in some" 6 "liver cancer: 3.6" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035225, HPA035226" Approved Nucleoplasm,Vesicles,Mitochondria Nucleoplasm "Vesicles, Mitochondria" "HPA035225: AB_10604002, HPA035226: AB_10696503" "unprognostic (1.87e-1)" "unprognostic (2.33e-1)" "unprognostic (4.22e-3)" "unprognostic (1.36e-3)" "unprognostic (2.29e-1)" "unprognostic (1.55e-1)" "unprognostic (3.53e-2)" "unprognostic (5.51e-2)" "unprognostic (5.11e-2)" "unprognostic (1.23e-2)" "unprognostic (4.65e-3)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (4.89e-2)" "unprognostic (2.78e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" 1.2 0.4 1.8 0.3 4.1 0.3 1.6 6.9 2.0 0.4 0.3 1.5 0.7 0.3 1.2 2.4 1.0 0.4 2.5 0.8 2.9 1.2 40.1 22.1 0.3 0.4 1.2 0.9 0.6 0.4 0.3 3.9 0.4 1.3 2.3 0.3 1.1 1.7 0.7 0.3 0.6 0.4 0.3 2.3 0.3 0.3 0.4 1.0 0.0 0.5 0.0 0.7 0.4 0.2 0.8 0.0 1.0 0.1 0.0 0.2 0.0 0.3 0.2 0.6 0.6 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.2 0.2 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.1 1.2 1.3 1.5 0.3 0.0 0.3 0.6 0.7 0.4 0.5 0.5 0.0 0.8 0.2 0.0 0.2 0.3 0.0 0.0 1.3 0.1 0.4 0.4 1.3 0.4 1.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.8 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.0 1.8 4.1 6.9 2.0 2.9 1.2 1.2 0.9 1.3 1.0 UQCRC1 "D3S3191, QCR1, UQCR1" ENSG00000010256 "Ubiquinol-cytochrome c reductase core protein 1" P31930 3 48599002-48610976 "Enzymes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 172.7" "Cell line enhanced" "Detected in all" "PC-3: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002815, HPA003525, CAB033782" Enhanced Supported Mitochondria,Cytosol 1300000 Mitochondria Cytosol "CAB033782: AB_2213631, HPA002815: AB_1080486, HPA003525: AB_1080484" "unprognostic (1.29e-1)" "unprognostic (3.15e-3)" "unprognostic (6.91e-3)" "unprognostic (1.06e-1)" "unprognostic (1.66e-1)" "unprognostic (9.91e-2)" "unprognostic (8.53e-2)" "unprognostic (1.99e-1)" "unprognostic (3.11e-2)" "unprognostic (9.14e-2)" "unprognostic (3.37e-1)" "unprognostic (7.20e-2)" "prognostic favourable (2.35e-10)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "unprognostic (1.02e-1)" "unprognostic (6.72e-2)" 18.1 13.7 11.1 9.8 12.5 9.4 11.8 12.5 20.5 11.0 33.7 6.9 10.4 20.0 9.1 9.7 15.8 12.4 10.8 66.7 10.8 11.2 23.0 30.5 7.7 9.3 13.3 13.5 6.3 14.4 20.4 7.8 11.5 13.3 12.5 12.3 7.8 19.5 21.9 172.7 14.0 20.9 12.0 8.7 8.4 23.0 18.4 7.4 9.4 9.1 39.9 9.8 10.3 9.1 23.3 52.7 28.1 57.8 15.1 22.0 74.3 10.0 16.2 5.9 3.6 8.7 8.0 26.7 18.5 15.0 15.4 14.0 25.2 3.0 25.9 11.7 8.3 9.7 7.4 21.5 2.8 15.4 35.5 26.6 14.1 27.4 17.3 16.7 11.5 11.0 24.4 10.5 17.2 15.2 14.3 1.7 9.3 17.4 12.0 19.1 14.8 64.6 8.2 15.7 21.2 15.9 11.0 6.3 11.2 25.1 3.0 14.8 6.4 2.6 15.3 4.3 16.3 13.4 19.1 15.8 13.9 15.0 9.4 19.3 13.7 17.6 57.8 28.1 18.9 56.9 17.9 23.3 18.9 19.0 52.7 18.6 17.1 16.4 14.1 15.1 48.5 21.0 22.0 74.3 11.1 12.5 12.5 20.5 10.8 11.2 13.3 13.5 13.3 7.4 UQCRC2 "QCR2, UQCR2" ENSG00000140740 "Ubiquinol-cytochrome c reductase core protein 2" P22695 16 21952660-21983660 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007998, HPA019146" Enhanced Enhanced Mitochondria 4000000 Mitochondria "HPA007998: AB_1858648, HPA019146: AB_1858649" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.49e-3)" "unprognostic (3.35e-1)" "unprognostic (1.26e-2)" "unprognostic (6.91e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (2.43e-2)" "prognostic favourable (6.58e-9)" "unprognostic (2.33e-1)" "unprognostic (9.78e-3)" "unprognostic (4.67e-3)" "unprognostic (7.36e-2)" 22.7 26.8 20.6 17.1 32.7 20.5 21.3 29.2 33.7 17.7 38.4 17.4 19.5 45.0 20.8 18.6 28.7 20.0 19.1 94.9 19.8 19.3 35.1 35.8 15.9 23.6 20.9 28.5 21.9 20.8 36.6 20.2 17.8 29.6 17.7 40.5 18.5 22.1 20.2 103.9 22.2 42.0 30.4 16.5 16.5 29.3 10.3 19.2 25.2 21.4 70.0 22.9 27.9 20.0 20.0 30.6 14.3 29.3 18.7 25.7 27.4 18.9 20.9 12.9 8.6 14.4 20.2 18.3 18.4 15.0 16.9 17.2 33.7 18.8 37.7 16.6 15.8 34.7 20.9 18.5 19.5 17.2 19.4 21.3 18.4 47.6 15.3 27.1 54.0 23.6 23.2 13.2 18.2 22.1 23.0 19.7 18.3 25.2 28.1 17.6 14.1 16.1 32.9 29.9 41.2 25.3 22.4 17.8 13.0 26.1 33.0 19.8 37.8 28.8 19.5 12.0 11.3 11.7 16.4 14.3 10.3 33.4 19.6 28.8 13.7 14.3 24.7 12.8 16.9 29.3 21.9 20.0 20.5 18.6 30.6 15.8 22.8 20.8 9.1 18.7 27.6 13.2 25.7 27.4 20.6 32.7 29.2 33.7 19.8 19.3 20.9 28.5 29.6 19.2 UQCRFS1 "RIP1, RIS1, RISP, UQCR5" ENSG00000169021 "Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1" P47985 19 29205321-29213541 "Enzymes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 112.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA041863, HPA050339" Enhanced Approved Mitochondria Mitochondria "HPA041863: AB_10794638, HPA050339: AB_2681095" "unprognostic (4.00e-2)" "unprognostic (2.23e-3)" "prognostic favourable (3.29e-4)" "unprognostic (7.91e-3)" "unprognostic (3.93e-2)" "unprognostic (8.68e-2)" "unprognostic (1.84e-1)" "unprognostic (7.53e-2)" "unprognostic (3.53e-2)" "prognostic unfavourable (3.84e-4)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "prognostic favourable (3.92e-9)" "unprognostic (6.11e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (1.92e-2)" 15.2 27.1 20.1 10.8 18.3 25.4 28.2 18.3 33.4 11.9 27.3 9.1 9.8 24.3 10.5 14.3 16.9 11.9 14.2 95.3 19.4 14.8 34.9 33.8 12.0 21.2 18.3 13.1 9.1 26.4 15.9 10.6 10.8 17.6 11.8 30.3 11.5 17.0 13.9 112.3 12.9 27.0 19.6 11.5 11.3 18.8 16.6 6.5 17.7 12.9 55.0 14.5 13.7 10.0 18.5 35.6 14.9 29.9 15.0 22.1 45.1 23.0 38.9 14.5 13.0 23.8 18.2 16.1 18.0 18.9 25.0 27.7 23.5 14.3 21.0 19.0 20.3 24.5 31.6 21.4 30.2 14.2 31.7 29.7 15.4 21.4 20.2 28.2 26.1 21.8 23.2 17.0 26.0 19.9 21.0 13.2 26.7 21.3 19.7 21.1 15.1 15.1 18.0 19.3 15.9 31.0 27.8 17.6 8.6 16.4 32.6 20.6 15.1 23.5 12.5 16.9 25.8 11.6 18.6 6.3 11.9 19.3 14.9 24.6 12.0 14.9 29.9 14.0 17.9 29.3 17.8 18.5 19.2 18.3 35.6 15.7 20.4 19.4 9.1 15.0 24.3 19.7 22.1 45.1 20.1 18.3 18.3 33.4 19.4 14.8 18.3 13.1 17.6 6.5 URAD PRHOXNB ENSG00000183463 "Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase" A6NGE7 13 27977714-27988654 "Enzymes, Predicted intracellular proteins" "Purine metabolism" "Decarboxylase, Lyase" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "breast: 8.8;intestine: 16.7" "Group enriched" "Detected in some" 13 "BEWO: 6.7;CACO-2: 6.1" "Cancer enriched" "Detected in some" 15 "colorectal cancer: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA038972 Uncertain "HPA038972: AB_10671869" "unprognostic (2.00e-1)" "unprognostic (1.05e-1)" "unprognostic (5.21e-2)" 2.8 0.0 0.1 1.5 0.1 0.0 8.8 0.6 0.1 0.1 16.7 0.1 0.1 8.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.9 0.1 0.1 0.1 0.1 0.0 16.0 0.2 0.1 0.1 0.0 0.2 0.1 0.6 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.1 UROC1 "FLJ31300, HMFN0320" ENSG00000159650 "Urocanate hydratase 1" Q96N76 3 126481281-126517773 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "liver: 50.7" "Cell line enriched" "Detected in some" 8 "NB-4: 9.3" "Cancer enriched" "Detected in single" 100 "liver cancer: 12.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enhanced" "Detected in single" "granulocytes: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069863 Enhanced 510000 "HPA069863: " "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (7.43e-2)" "unprognostic (6.43e-2)" "unprognostic (1.43e-1)" "unprognostic (2.23e-3)" "unprognostic (2.95e-1)" "unprognostic (2.57e-2)" "unprognostic (7.71e-2)" "unprognostic (9.97e-2)" "unprognostic (3.04e-1)" "unprognostic (3.65e-5)" "unprognostic (3.97e-2)" "unprognostic (2.66e-1)" "unprognostic (5.52e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 50.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UROD ENSG00000126088 "Uroporphyrinogen decarboxylase" P06132 1 45012147-45015575 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" "Decarboxylase, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 79.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027468, HPA028668, HPA030350" Uncertain Supported Nucleoplasm,Cytosol 5200000 "Nucleoplasm, Cytosol" "HPA027468: AB_1858654, HPA028668: AB_10603458, HPA030350: " "unprognostic (5.90e-2)" "unprognostic (2.94e-2)" "unprognostic (2.49e-1)" "unprognostic (9.61e-2)" "unprognostic (7.94e-2)" "unprognostic (1.96e-1)" "prognostic unfavourable (2.48e-4)" "unprognostic (2.31e-2)" "unprognostic (4.76e-2)" "unprognostic (6.75e-2)" "unprognostic (7.72e-3)" "unprognostic (3.92e-1)" "unprognostic (1.24e-1)" "unprognostic (4.68e-2)" "unprognostic (1.41e-1)" "unprognostic (8.73e-2)" "unprognostic (8.12e-2)" 20.7 50.2 23.1 12.2 26.2 67.5 20.7 14.2 28.6 17.7 24.2 16.5 25.9 11.2 27.8 22.6 17.8 20.8 17.4 34.0 21.1 20.3 29.6 58.1 14.3 14.8 21.6 22.9 27.4 18.4 35.9 17.6 25.8 16.2 19.2 12.3 24.3 45.6 19.2 28.8 12.1 13.2 22.9 18.9 16.6 15.0 16.3 11.5 17.2 26.3 23.6 16.0 15.0 13.0 25.7 48.6 20.6 36.3 26.0 27.4 35.6 12.5 8.2 13.2 17.3 22.8 21.5 6.4 15.3 39.6 32.3 24.9 11.8 6.6 8.9 16.2 23.2 6.5 25.1 29.9 22.5 7.9 26.4 46.0 19.0 39.1 26.6 14.0 8.6 22.3 19.0 30.8 25.0 41.4 79.8 9.8 30.8 10.5 9.5 12.1 20.5 29.1 14.4 19.6 12.9 28.1 10.6 14.1 11.1 16.8 12.6 25.9 9.9 14.7 26.8 18.4 14.4 6.3 24.7 10.2 10.9 7.5 28.8 21.3 9.2 17.6 36.3 20.6 19.7 25.8 20.0 25.7 23.8 19.2 48.6 23.7 22.3 20.3 6.6 26.0 15.5 32.4 27.4 35.6 23.1 26.2 14.2 28.6 21.1 20.3 21.6 22.9 16.2 11.5 UROS ENSG00000188690 "Uroporphyrinogen III synthase" P10746 10 125784980-125823248 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044038 Approved Approved Nucleoplasm,Cytosol 15000 Nucleoplasm Cytosol "HPA044038: AB_10966692" "unprognostic (8.86e-2)" "unprognostic (7.64e-2)" "unprognostic (2.77e-1)" "unprognostic (7.19e-2)" "unprognostic (1.90e-1)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (5.82e-2)" "unprognostic (1.27e-1)" "unprognostic (4.35e-3)" "unprognostic (4.23e-3)" "unprognostic (2.00e-2)" "prognostic unfavourable (6.27e-4)" "unprognostic (1.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (3.93e-1)" 13.8 16.1 48.6 9.0 46.6 33.2 13.9 12.8 35.3 8.9 11.4 15.7 12.8 13.2 9.3 41.2 10.5 11.3 11.5 31.4 36.9 20.4 22.6 25.5 10.0 16.8 22.7 23.4 14.5 14.1 14.4 12.0 7.9 20.0 12.9 12.4 14.0 18.1 14.0 45.6 9.8 12.0 13.0 12.5 11.7 12.5 13.8 13.8 10.8 16.4 14.4 12.7 9.4 6.3 17.3 27.1 2.4 15.6 24.7 21.3 17.8 17.4 18.9 13.8 30.7 18.5 18.8 18.6 22.6 39.1 15.9 15.9 8.2 21.3 24.4 10.6 28.0 10.0 8.0 16.1 15.0 30.1 15.2 51.8 10.7 13.5 26.1 21.8 12.2 23.5 9.2 11.1 29.8 14.5 8.9 23.2 26.5 20.8 19.1 24.6 15.0 19.8 13.5 15.3 14.5 20.8 10.9 10.8 18.6 22.6 17.4 30.7 15.6 20.8 14.4 21.1 7.9 16.2 19.1 21.4 15.5 16.6 29.4 8.9 10.0 2.4 15.6 2.2 16.1 15.4 18.5 15.7 16.0 20.4 27.1 17.3 21.3 16.3 1.2 24.7 14.6 12.9 14.2 17.8 48.6 46.6 12.8 35.3 36.9 20.4 22.7 23.4 20.0 13.8 USP1 ENSG00000162607 "Ubiquitin specific peptidase 1" O94782 1 62436297-62451804 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028387, HPA028440" Approved Supported Nucleoplasm Nucleoplasm "HPA028387: , HPA028440: AB_10603000" "unprognostic (1.22e-1)" "unprognostic (5.36e-2)" "unprognostic (1.78e-3)" "unprognostic (4.05e-3)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "prognostic unfavourable (5.81e-5)" "unprognostic (6.72e-2)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.33e-3)" "unprognostic (3.99e-2)" "unprognostic (2.76e-2)" "unprognostic (9.61e-3)" "unprognostic (5.70e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" 11.6 9.0 11.3 17.2 10.7 29.3 15.9 20.6 14.2 19.2 13.3 7.8 8.0 10.8 15.1 12.0 15.6 13.8 8.9 9.0 11.5 9.6 11.8 9.3 11.7 19.2 14.2 9.6 26.7 12.7 14.8 18.4 13.6 10.9 14.8 13.9 7.6 12.7 13.5 11.7 12.3 13.3 15.8 15.5 18.1 11.6 31.6 11.8 70.6 15.0 13.3 20.1 16.5 16.5 14.7 11.8 23.4 12.4 15.5 16.3 9.2 22.0 6.5 27.4 14.8 6.2 7.4 15.2 21.2 14.5 26.4 29.0 11.0 10.8 39.9 15.4 11.9 12.8 22.5 14.6 37.0 19.9 16.2 32.7 22.6 11.5 6.7 35.0 16.5 3.9 9.6 23.9 18.0 12.4 23.7 34.9 18.6 9.8 35.9 13.5 24.1 13.5 34.1 46.5 24.7 9.9 16.5 28.4 15.9 24.0 19.6 23.2 11.2 21.4 8.6 20.4 22.2 29.8 29.7 13.9 19.3 45.8 13.8 28.0 18.2 17.4 9.5 23.4 12.6 9.6 16.3 14.7 15.0 12.7 11.4 10.7 14.3 11.9 16.9 15.5 12.4 11.8 13.6 9.2 11.3 10.7 20.6 14.2 11.5 9.6 14.2 9.6 10.9 11.8 USP10 "KIAA0190, UBPO" ENSG00000103194 "Ubiquitin specific peptidase 10" Q14694 16 84699978-84779922 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 105.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "neutrophil: 105.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 105.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006731, HPA006749" Enhanced Enhanced Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA006731: AB_1080495, HPA006749: AB_1080492" "unprognostic (4.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.36e-2)" "unprognostic (4.85e-2)" "unprognostic (6.93e-2)" "unprognostic (1.77e-3)" "unprognostic (1.03e-3)" "unprognostic (2.91e-3)" "unprognostic (1.75e-1)" "unprognostic (3.84e-2)" "unprognostic (2.56e-2)" "unprognostic (1.82e-3)" "prognostic favourable (1.00e-4)" "unprognostic (5.91e-2)" "unprognostic (4.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.38e-1)" 13.9 18.8 16.0 24.2 19.0 13.4 14.4 24.4 20.4 15.9 18.1 15.6 8.4 16.1 20.2 10.4 19.7 18.2 12.0 16.4 19.3 15.1 16.4 20.7 13.7 18.8 19.7 17.4 18.5 17.1 35.8 15.0 23.5 16.2 15.0 15.6 17.9 15.3 17.8 47.0 17.0 17.5 20.2 16.3 16.0 15.0 15.5 16.2 20.4 17.6 15.7 20.9 19.7 15.8 7.2 10.4 105.5 8.6 7.7 17.3 10.0 13.6 18.9 18.4 22.8 6.8 11.6 24.9 13.5 14.3 22.9 12.6 26.6 11.9 23.7 15.7 14.1 15.7 25.5 21.5 30.5 9.6 13.4 13.6 8.9 17.6 9.0 20.2 8.3 7.3 16.6 23.9 27.7 17.5 37.1 5.2 15.8 28.6 20.9 9.8 22.1 12.8 27.2 10.1 11.2 14.4 11.1 17.2 10.1 32.3 10.5 9.1 24.1 12.9 12.8 15.9 12.7 8.0 12.8 8.7 12.1 60.1 10.3 13.0 16.3 2.5 8.6 1.6 5.7 7.0 6.8 7.2 17.3 6.3 10.4 6.7 9.9 6.0 105.5 7.7 6.3 3.5 6.1 10.0 16.0 19.0 24.4 20.4 19.3 15.1 19.7 17.4 16.2 16.2 USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232690-47248328 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 74.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA003103: AB_10671088, HPA037536: AB_10672904" "unprognostic (1.60e-1)" "unprognostic (2.77e-3)" "unprognostic (5.84e-2)" "prognostic unfavourable (2.95e-4)" "unprognostic (3.08e-2)" "unprognostic (2.02e-1)" "unprognostic (6.11e-3)" "unprognostic (9.21e-2)" "unprognostic (3.18e-2)" "unprognostic (3.52e-1)" "unprognostic (3.29e-3)" "unprognostic (3.74e-2)" "prognostic favourable (4.13e-5)" "unprognostic (3.14e-2)" "unprognostic (9.23e-2)" "unprognostic (9.51e-2)" "unprognostic (7.11e-2)" 11.5 17.3 32.9 11.5 55.0 4.9 9.4 35.7 74.0 17.5 9.1 19.9 5.8 6.0 22.6 12.7 9.7 26.6 12.8 20.6 27.0 44.0 13.6 6.7 12.5 13.8 23.1 47.4 38.2 13.8 28.4 32.3 12.6 27.8 15.7 7.6 17.9 9.3 21.3 13.7 7.8 7.3 19.1 17.0 13.5 9.1 19.2 14.6 19.0 27.2 4.3 14.3 11.0 9.8 21.0 20.6 22.8 8.7 19.8 31.7 16.4 14.3 22.6 38.9 26.5 14.7 9.9 10.8 11.0 17.3 21.9 24.5 21.5 11.8 9.5 8.7 19.8 17.1 31.5 7.7 19.5 14.7 23.9 11.1 17.9 19.1 17.1 12.4 23.2 14.2 3.2 23.1 9.9 8.7 8.3 1.3 17.0 21.8 24.1 13.3 28.9 20.2 27.2 38.1 7.9 10.7 19.8 22.0 37.8 20.1 4.1 11.9 8.5 7.2 9.1 18.5 19.5 26.0 12.5 17.7 11.1 16.6 11.4 15.5 16.4 22.8 3.5 7.4 22.6 7.4 19.9 20.1 10.2 22.1 4.6 21.0 15.4 31.7 2.2 19.8 8.7 20.6 12.7 16.4 32.9 55.0 35.7 74.0 27.0 44.0 23.1 47.4 27.8 14.6 USP12 USP12L1 ENSG00000152484 "Ubiquitin specific peptidase 12" O75317 13 27066142-27171896 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, HPA059492" Uncertain Approved Nucleoplasm Nucleoplasm "HPA007288: AB_1080531, HPA059492: " "unprognostic (6.72e-3)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (5.85e-2)" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "unprognostic (8.38e-2)" "unprognostic (8.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.91e-1)" "unprognostic (6.77e-2)" "unprognostic (1.73e-1)" 15.7 10.4 18.3 23.3 17.8 46.0 15.6 16.6 18.3 12.1 30.6 16.1 8.8 13.0 15.3 11.6 23.5 9.5 14.5 11.3 19.3 15.9 18.3 27.9 19.9 19.6 20.5 7.5 12.0 13.4 10.7 16.2 14.8 12.4 17.5 19.1 10.1 8.9 9.5 9.8 17.3 33.0 43.8 18.5 16.5 14.7 11.0 13.1 8.4 12.0 6.6 18.5 42.8 24.2 4.6 3.0 5.3 2.1 2.3 3.6 1.2 12.0 7.6 14.6 7.5 9.8 12.5 5.2 17.0 12.0 9.5 7.1 13.7 19.0 17.2 8.6 13.4 7.5 9.5 9.9 20.3 27.7 8.2 26.6 9.9 9.6 12.3 15.3 18.7 7.8 14.5 10.7 12.3 21.8 8.8 8.4 19.6 7.0 9.4 20.5 10.4 13.5 10.8 18.6 4.0 18.7 8.6 16.1 9.7 14.6 12.3 13.8 5.8 15.0 25.7 9.9 9.6 21.2 15.4 6.4 7.1 12.3 16.7 9.2 11.0 0.0 1.2 5.3 1.5 1.3 2.5 3.2 2.4 2.0 1.6 4.6 1.6 1.7 1.2 2.3 2.1 3.0 3.6 1.2 18.3 17.8 16.6 15.5 19.3 15.9 20.5 7.5 12.4 13.1 USP13 IsoT-3 ENSG00000058056 "Ubiquitin specific peptidase 13" Q92995 3 179652755-179789401 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 34.8;skeletal muscle: 90.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "MAIT T-cell: 15.4" "Lineage enriched" "Detected in many" 8 "T-cells: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004827 Enhanced Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA004827: AB_1080497" "unprognostic (1.00e-2)" "unprognostic (2.09e-1)" "unprognostic (5.82e-2)" "unprognostic (7.14e-2)" "unprognostic (9.94e-2)" "unprognostic (3.96e-2)" "prognostic unfavourable (2.40e-5)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (7.79e-2)" "unprognostic (1.69e-3)" "unprognostic (2.22e-2)" "prognostic unfavourable (3.46e-6)" "unprognostic (4.93e-2)" "unprognostic (9.79e-2)" "unprognostic (3.38e-2)" "prognostic unfavourable (3.06e-4)" 6.4 7.5 2.0 2.3 2.8 0.8 3.5 2.9 4.1 2.7 2.1 4.6 1.5 0.7 3.2 3.8 2.6 2.5 2.5 34.8 2.0 2.3 2.3 3.4 6.0 2.5 2.1 2.1 7.2 3.0 3.3 9.8 1.9 3.0 3.0 1.8 3.1 3.3 2.1 90.3 1.8 1.7 3.7 2.5 1.6 1.6 5.6 1.3 1.7 5.5 17.1 3.2 2.6 1.9 2.0 1.9 0.0 0.4 0.0 15.4 0.7 12.3 5.3 10.1 7.7 4.6 6.4 4.9 7.3 8.4 10.8 9.1 7.8 4.4 15.3 8.2 8.8 0.9 11.3 4.4 12.9 36.2 4.8 4.0 8.0 7.3 3.3 11.2 0.0 6.8 1.6 8.4 10.7 8.6 1.9 19.8 8.9 8.1 6.8 2.0 7.8 4.8 11.7 10.0 12.5 7.3 3.5 5.7 7.4 7.0 9.4 4.2 16.2 8.1 9.3 13.0 10.4 11.1 28.1 9.6 8.0 31.4 6.0 7.6 12.1 0.0 0.2 0.0 1.3 0.4 15.4 2.0 1.3 2.9 1.5 0.6 1.0 1.0 0.0 0.0 0.4 1.9 0.6 0.7 2.0 2.8 2.9 4.1 2.0 2.3 2.1 2.1 3.0 1.3 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported Cytosol 1400000 Cytosol "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavourable (7.81e-5)" "prognostic unfavourable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favourable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 24.8 24.2 25.9 20.7 32.1 19.4 21.7 21.7 28.4 16.5 17.1 17.9 19.1 13.4 19.4 24.3 25.3 14.7 14.4 23.3 22.1 27.6 23.2 24.4 15.8 21.9 22.6 28.8 16.2 16.2 22.3 18.0 25.1 29.2 29.9 19.4 14.5 16.7 20.5 53.3 15.7 12.9 23.9 22.1 15.4 15.6 17.2 16.5 19.5 20.1 25.4 28.6 17.8 17.8 13.1 15.2 7.7 15.2 23.0 21.2 11.0 26.8 22.1 18.8 19.1 18.7 18.7 33.7 35.3 19.4 36.0 33.6 28.7 14.4 39.9 27.0 28.9 15.1 37.1 27.0 41.1 11.3 18.3 22.5 14.8 22.5 18.7 55.2 21.6 14.9 20.9 36.7 21.1 27.6 31.0 29.7 35.4 21.8 30.8 15.1 18.4 26.0 25.7 24.7 29.1 26.6 23.3 22.0 18.5 36.6 17.7 15.0 17.3 14.9 31.2 42.3 32.0 38.8 50.0 19.6 35.6 39.7 24.4 23.0 26.3 5.0 10.7 7.7 17.8 15.2 21.2 13.1 17.7 18.4 15.2 10.1 17.5 16.9 0.8 23.0 11.4 11.1 16.7 11.0 25.9 32.1 21.7 27.1 22.1 27.6 22.6 28.8 29.2 16.5 USP15 "KIAA0529, UNPH4" ENSG00000135655 "Ubiquitin specific peptidase 15" Q9Y4E8 12 62260338-62417431 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 68.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006237, HPA006428, HPA071014" Approved Enhanced Cytosol 280000 Cytosol "HPA006237: AB_1080502, HPA006428: , HPA071014: " "unprognostic (8.18e-2)" "unprognostic (3.22e-1)" "unprognostic (9.63e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.75e-1)" "prognostic unfavourable (8.04e-4)" "unprognostic (6.59e-2)" "unprognostic (7.70e-3)" "unprognostic (2.19e-1)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "prognostic unfavourable (1.58e-5)" "unprognostic (9.28e-2)" "unprognostic (5.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" 23.1 16.8 11.5 22.5 11.9 88.9 17.8 21.1 15.7 14.5 14.5 5.2 11.9 11.4 12.7 12.4 16.1 14.1 11.2 15.2 9.6 6.2 13.8 20.4 23.8 26.2 11.6 9.4 22.5 15.8 18.9 22.5 31.0 14.9 12.4 13.8 7.6 16.2 10.7 28.5 23.0 19.7 16.3 16.2 35.6 14.3 20.0 11.0 33.1 14.1 15.4 18.9 18.4 17.9 5.7 6.0 68.5 14.2 3.3 12.1 4.8 9.3 8.8 8.8 7.6 13.9 16.3 15.7 15.2 13.5 13.5 12.1 8.8 9.4 10.0 8.7 13.0 10.2 11.7 13.2 15.8 11.0 7.2 13.7 7.5 6.7 13.5 21.7 33.4 11.8 13.8 15.9 14.2 15.9 44.4 19.4 12.4 10.4 12.9 11.0 12.9 13.0 8.3 9.3 16.1 12.5 10.8 11.1 5.3 17.6 11.2 8.6 14.7 13.0 19.0 10.5 10.5 16.3 9.4 9.2 10.2 11.4 12.0 17.7 11.8 27.2 14.2 13.8 3.4 7.3 3.5 5.7 4.6 3.2 4.9 4.7 5.9 3.5 68.5 3.3 5.8 6.0 12.1 4.8 11.5 11.9 21.1 15.7 9.6 6.2 11.6 9.4 14.9 11.0 USP16 Ubp-M ENSG00000156256 "Ubiquitin specific peptidase 16" Q9Y5T5 21 29024629-29054488 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021140 Supported Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA021140: AB_1858668" "unprognostic (6.06e-2)" "unprognostic (3.14e-1)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (5.92e-2)" "unprognostic (5.79e-3)" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (5.78e-2)" "unprognostic (7.40e-2)" "unprognostic (8.73e-2)" "unprognostic (8.65e-2)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (1.55e-1)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" 25.4 21.7 24.4 27.4 24.2 20.4 22.8 32.4 23.1 24.2 24.3 13.5 23.6 20.4 22.6 28.2 27.1 19.4 17.0 23.8 23.8 22.6 28.4 34.0 16.8 20.7 25.8 19.5 27.3 23.6 31.6 41.6 45.9 25.3 26.0 22.3 13.3 20.6 28.8 35.8 16.1 33.2 26.2 28.6 29.1 20.8 20.1 25.3 37.6 28.4 25.6 25.5 30.8 17.1 30.9 23.5 21.2 20.5 19.9 26.2 10.1 21.8 8.7 13.9 12.5 9.9 16.3 13.1 21.3 14.2 14.8 14.1 10.9 14.2 22.3 6.5 20.4 10.0 17.2 15.5 19.4 21.3 18.3 29.7 10.6 12.1 14.7 29.1 16.5 13.9 16.4 19.3 17.8 14.2 24.4 39.4 17.1 10.0 17.9 10.6 14.8 11.3 12.0 34.3 25.5 12.2 15.8 15.1 16.1 13.8 22.1 18.7 15.2 20.0 14.2 17.3 21.6 15.9 21.9 33.7 46.2 23.4 18.1 21.2 17.2 21.2 16.2 20.9 25.4 16.1 19.8 26.4 23.9 22.8 14.9 30.9 26.2 24.8 15.5 19.9 20.5 23.5 24.5 10.1 24.4 24.2 32.4 23.1 23.8 22.6 25.8 19.5 25.3 25.3 USP17L1 USP17L1P ENSG00000230549 "Ubiquitin specific peptidase 17-like family member 1" Q7RTZ2 8 7332387-7333979 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in single" "brain: 2.1" "Cell line enhanced" "Detected in single" "AN3-CA: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L10 ENSG00000231396 "Ubiquitin specific peptidase 17-like family member 10" C9JJH3 4 9210657-9212608 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L11 ENSG00000233136 "Ubiquitin specific peptidase 17-like family member 11" C9JVI0 4 9215405-9217356 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "blood: 1.0;fallopian tube: 1.2;thyroid gland: 1.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.5;NTERA-2: 1.6" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 11 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 11 "dendritic cells: 1.0" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 USP17L12 ENSG00000227551 "Ubiquitin specific peptidase 17-like family member 12" C9JPN9 4 9220152-9221744 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L13 ENSG00000232399 "Ubiquitin specific peptidase 17-like family member 13" C9JLJ4 4 9224896-9226847 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L15 ENSG00000223569 "Ubiquitin specific peptidase 17-like family member 15" C9J2P7 4 9234385-9236334 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "brain: 1.0;epididymis: 1.0" "Cell line enhanced" "Detected in single" "U-87 MG: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.2 1.0 0.0 0.3 0.0 0.1 0.3 0.4 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L17 ENSG00000249104 "Ubiquitin specific peptidase 17-like family member 17" D6RBQ6 4 9243879-9245830 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in single" "thyroid gland: 1.0" "Cell line enhanced" "Detected in some" "HDLM-2: 1.2;NTERA-2: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L18 ENSG00000250844 "Ubiquitin specific peptidase 17-like family member 18" D6R9N7 4 9248630-9250581 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L19 ENSG00000248920 "Ubiquitin specific peptidase 17-like family member 19" D6RCP7 4 9253378-9255329 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L2 DUB3 ENSG00000223443 "Ubiquitin specific peptidase 17-like family member 2" Q6R6M4 8 12137168-12139077 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell line enhanced" "Detected in single" "HEK 293: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " "unprognostic (2.01e-1)" 0.1 0.4 0.1 0.1 0.5 0.0 0.2 0.8 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 1.0 1.1 0.0 0.3 0.1 0.1 0.4 0.0 0.1 0.1 0.1 0.1 0.6 0.1 0.1 0.1 0.2 0.0 0.5 0.1 0.1 0.2 0.1 0.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.1 0.1 0.0 0.1 0.1 0.1 0.1 USP17L20 ENSG00000250745 "Ubiquitin specific peptidase 17-like family member 20" D6RJB6 4 9258124-9260075 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTERT-HME1: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L21 ENSG00000249811 "Ubiquitin specific peptidase 17-like family member 21" D6R901 4 9262872-9264823 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L22 ENSG00000248933 "Ubiquitin specific peptidase 17-like family member 22" D6RA61 4 9267619-9269570 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 USP17L24 ENSG00000232264 "Ubiquitin specific peptidase 17-like family member 24" Q0WX57 4 9325165-9327116 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L25 ENSG00000230430 "Ubiquitin specific peptidase 17-like family member 25" Q0WX57 4 9329911-9331862 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L26 ENSG00000229579 "Ubiquitin specific peptidase 17-like family member 26" Q0WX57 4 9334658-9336609 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L27 ENSG00000235780 "Ubiquitin specific peptidase 17-like family member 27" Q0WX57 4 9344148-9345740 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L28 ENSG00000231051 "Ubiquitin specific peptidase 17-like family member 28" Q0WX57 4 9348893-9350485 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L29 ENSG00000231637 "Ubiquitin specific peptidase 17-like family member 29" Q0WX57 4 9353638-9355230 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L3 "USP17B, USP17F" ENSG00000225327 "Ubiquitin specific peptidase 17-like family member 3" A6NCW0 8 7976393-7977985 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L30 ENSG00000228856 "Ubiquitin specific peptidase 17-like family member 30" Q0WX57 4 9363129-9364721 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L4 ENSG00000236125 "Ubiquitin specific peptidase 17-like family member 4" A6NCW7 8 7337115-7338707 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L5 ENSG00000227140 "Ubiquitin specific peptidase 17-like family member 5" A8MUK1 4 9339403-9340995 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L7 ENSG00000226430 "Ubiquitin specific peptidase 17-like family member 7" P0C7H9 8 12132417-12134438 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEK 293: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " "unprognostic (5.31e-2)" 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.5 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 USP17L8 ENSG00000237038 "Ubiquitin specific peptidase 17-like family member 8" P0C7I0 8 7971661-7973253 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 USP18 ENSG00000184979 "Ubiquitin specific peptidase 18" Q9UMW8 22 18149899-18177397 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 48.0;BJ hTERT+ SV40 Large T+ RasG12V: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA044768 Uncertain Approved Cytosol Cytosol "HPA044768: AB_10963697" "unprognostic (2.06e-1)" "unprognostic (3.55e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (5.42e-2)" "unprognostic (3.29e-2)" "unprognostic (5.11e-3)" "unprognostic (1.81e-1)" "unprognostic (1.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (4.29e-3)" "unprognostic (2.58e-1)" "unprognostic (2.77e-2)" "unprognostic (2.28e-2)" "unprognostic (8.38e-2)" 20.4 6.4 4.8 13.0 4.8 6.3 15.4 1.9 5.5 5.3 6.3 5.6 3.2 5.2 6.1 9.5 6.0 6.5 7.1 5.4 4.4 4.6 8.8 20.9 14.0 15.9 4.3 4.8 4.9 4.2 3.8 7.8 7.6 4.7 4.8 3.9 5.7 11.7 2.3 9.7 4.2 15.5 4.5 4.1 10.6 6.4 10.6 4.0 22.4 10.6 2.9 7.7 4.3 6.9 4.1 2.9 6.6 8.8 11.0 11.0 4.8 3.7 3.7 1.1 4.8 4.9 3.6 4.9 1.9 4.5 48.0 52.3 0.6 5.2 0.0 2.9 1.0 1.3 5.6 1.6 1.6 16.4 7.8 7.2 0.5 6.8 0.5 1.7 6.9 1.6 0.6 3.4 0.0 10.6 0.3 0.4 0.4 6.3 8.3 4.2 3.4 2.9 3.3 7.5 0.0 0.9 3.1 4.0 3.2 2.3 3.9 17.8 2.6 1.7 17.4 0.3 0.9 1.1 1.9 0.9 11.2 0.0 4.3 4.3 2.7 2.7 3.2 6.6 7.8 8.8 10.0 4.1 6.7 10.1 1.6 2.7 7.9 8.8 0.5 11.0 6.6 2.9 11.0 4.8 4.8 4.8 1.9 4.0 4.4 4.6 4.3 4.8 4.7 4.0 USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381726 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 79.9" "Cell line enriched" "Detected in many" 4 "U-266/70: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "naive CD4 T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA006777: AB_1080507, HPA007222: AB_1080505" "unprognostic (6.83e-2)" "unprognostic (2.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-3)" "unprognostic (8.02e-3)" "unprognostic (7.33e-2)" "prognostic favourable (3.09e-11)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (2.66e-2)" 3.1 4.8 6.9 1.4 12.2 1.5 1.6 12.6 16.1 2.5 5.9 10.0 0.0 7.9 2.6 6.4 5.9 7.0 2.2 26.8 5.7 3.1 29.7 10.6 2.2 0.7 5.7 6.2 2.9 10.1 18.4 7.6 1.3 6.7 2.3 3.9 19.1 3.2 2.4 79.9 4.6 11.7 4.2 3.8 0.8 2.7 36.1 8.8 0.0 2.2 25.2 1.0 1.9 2.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 3.4 0.3 0.5 1.9 0.1 0.1 0.7 0.4 0.2 0.0 0.3 3.6 0.5 5.9 1.1 0.6 0.6 4.7 1.7 0.1 4.2 0.6 1.7 2.5 7.3 1.6 0.0 1.6 0.6 0.3 0.4 1.2 0.3 8.2 0.5 1.0 2.4 0.0 0.4 0.9 0.7 0.0 1.3 0.8 2.7 0.2 7.2 2.2 2.0 1.6 0.4 5.3 3.6 0.0 0.0 0.9 0.5 0.5 34.4 7.6 0.1 0.0 1.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.0 1.3 0.7 0.0 0.0 0.0 0.0 0.3 0.3 6.9 12.2 12.6 16.1 5.7 3.1 5.7 6.2 6.7 8.8 USP20 KIAA1003 ENSG00000136878 "Ubiquitin specific peptidase 20" Q9Y2K6 9 129834698-129881838 "Enzymes, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 30.4;MOLT-4: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006287, HPA007008" Uncertain Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "HPA006287: AB_1080510, HPA007008: " "unprognostic (2.64e-2)" "prognostic favourable (8.01e-4)" "prognostic unfavourable (2.48e-4)" "prognostic favourable (4.01e-4)" "unprognostic (4.69e-1)" "unprognostic (1.89e-2)" "unprognostic (2.25e-1)" "unprognostic (2.55e-3)" "unprognostic (1.24e-1)" "unprognostic (7.89e-2)" "prognostic favourable (1.54e-7)" "unprognostic (2.09e-1)" "prognostic favourable (5.65e-5)" "unprognostic (1.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-2)" "unprognostic (1.24e-2)" 7.8 13.2 10.5 15.2 14.6 24.4 8.5 23.0 19.6 13.2 12.1 12.7 10.2 9.7 13.3 6.2 9.3 11.6 12.5 8.8 10.5 13.7 8.0 7.3 9.1 19.6 9.6 16.1 16.8 12.9 11.5 19.0 8.0 11.9 14.9 6.1 10.8 13.7 17.2 10.2 14.0 11.8 20.0 8.8 14.6 10.2 14.0 8.8 51.5 19.3 4.2 15.3 15.6 10.0 3.8 2.4 4.8 1.7 9.0 10.7 5.4 3.0 2.9 5.2 7.0 6.8 5.8 7.4 4.9 4.1 3.7 2.6 2.4 3.3 4.1 4.2 4.7 7.6 3.1 3.5 1.5 22.2 4.1 7.6 8.0 1.6 4.8 7.1 5.7 5.1 5.1 4.9 3.7 4.0 30.4 5.1 2.2 8.0 27.8 16.9 4.1 7.0 4.7 5.8 7.0 2.9 3.3 1.1 5.8 5.7 7.2 4.6 7.5 10.0 5.9 4.1 1.9 5.5 3.2 5.1 7.4 2.9 8.2 9.4 3.8 1.0 1.7 4.8 8.6 1.4 9.3 3.7 8.8 8.3 2.4 3.8 10.4 8.9 2.8 9.0 1.3 2.1 10.7 5.4 10.5 14.6 23.0 19.6 10.5 13.7 9.6 16.1 11.9 8.8 USP21 "USP16, USP23" ENSG00000143258 "Ubiquitin specific peptidase 21" Q9UK80 1 161159450-161165723 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028397 Uncertain Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" Cytosol "Nucleoplasm, Plasma membrane" "HPA028397: AB_10603227" "unprognostic (9.17e-2)" "unprognostic (1.44e-1)" "unprognostic (3.95e-2)" "prognostic unfavourable (7.05e-4)" "unprognostic (1.22e-2)" "unprognostic (1.26e-2)" "prognostic unfavourable (1.68e-4)" "unprognostic (5.35e-2)" "unprognostic (6.73e-2)" "unprognostic (2.76e-2)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "prognostic unfavourable (9.50e-6)" "unprognostic (2.45e-1)" "unprognostic (3.28e-1)" "unprognostic (2.13e-2)" "prognostic favourable (3.35e-5)" 11.8 16.4 22.1 12.8 21.2 15.3 19.1 23.6 24.8 18.1 16.1 25.5 14.0 15.5 19.7 14.6 18.3 33.3 14.1 13.7 20.9 12.1 15.4 10.6 14.0 16.7 26.4 14.1 28.3 19.0 24.4 17.2 15.2 20.5 18.1 13.1 17.1 19.0 25.3 19.4 23.5 15.4 15.1 17.0 18.7 16.0 17.0 22.9 16.0 24.5 9.6 15.6 17.9 19.2 14.1 12.0 18.3 11.1 13.4 17.2 10.7 7.4 12.8 16.9 16.3 13.5 11.3 10.4 5.5 9.0 15.2 11.9 11.8 14.7 9.7 9.5 6.8 12.9 10.9 10.7 8.4 18.5 18.3 11.6 18.5 9.2 9.7 10.3 8.7 9.5 14.4 10.4 15.0 10.7 17.1 13.6 9.6 13.7 18.2 16.2 15.8 16.3 17.3 5.6 16.3 8.9 8.9 15.4 19.8 10.3 10.8 8.3 23.8 16.6 6.2 10.9 9.7 7.6 9.4 27.5 21.3 14.4 10.0 8.9 9.8 13.0 11.1 18.3 14.9 7.1 17.2 12.8 13.8 15.4 12.0 14.1 16.0 14.6 9.6 13.4 7.7 12.0 13.3 10.7 22.1 21.2 23.6 24.8 20.9 12.1 26.4 14.1 20.5 22.9 USP22 "KIAA1063, USP3L" ENSG00000124422 "Ubiquitin specific peptidase 22" Q9UPT9 17 20999593-21043760 "Enzymes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044980 Supported Approved "Nuclear speckles" "Nuclear speckles" "HPA044980: AB_10794503" "unprognostic (7.24e-2)" "unprognostic (5.38e-2)" "unprognostic (7.67e-2)" "unprognostic (6.19e-2)" "unprognostic (4.72e-1)" "unprognostic (1.11e-2)" "prognostic unfavourable (9.66e-4)" "unprognostic (2.17e-2)" "unprognostic (7.81e-2)" "unprognostic (6.37e-2)" "unprognostic (1.07e-3)" "unprognostic (5.68e-2)" "prognostic favourable (1.53e-7)" "unprognostic (8.95e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (1.79e-2)" 22.5 33.0 40.7 21.5 49.5 25.9 24.6 66.1 66.4 26.8 23.6 31.9 25.1 18.9 36.7 29.3 21.9 33.9 23.0 44.1 38.7 47.6 27.7 22.9 26.1 25.1 31.0 40.7 45.6 24.5 47.4 32.2 22.4 35.1 27.5 20.5 28.7 20.0 29.5 47.6 22.1 21.1 31.2 24.8 23.7 22.7 20.2 23.7 41.2 32.8 24.8 27.3 25.1 23.2 13.7 12.1 13.4 13.3 8.9 15.5 6.9 21.6 39.4 38.3 32.9 22.4 23.3 18.3 25.0 19.3 22.6 19.2 45.4 9.8 29.8 24.1 38.4 23.4 37.1 29.8 33.8 14.2 25.7 24.7 26.2 22.0 26.5 27.1 21.6 25.6 17.9 25.5 26.9 28.1 28.0 10.8 31.9 22.3 37.9 12.9 19.7 13.0 42.0 60.6 20.3 20.8 31.9 18.5 38.1 32.3 13.4 26.3 22.5 16.1 35.6 23.1 30.7 23.6 33.8 11.7 15.6 99.0 23.5 14.5 35.6 6.8 13.3 12.6 11.0 9.8 11.1 10.9 11.7 10.9 12.1 13.7 15.5 14.6 13.4 8.9 12.2 10.2 7.8 6.9 40.7 49.5 66.1 66.4 38.7 47.6 31.0 40.7 35.1 23.7 USP24 KIAA1057 ENSG00000162402 "Ubiquitin specific peptidase 24" Q9UPU5 1 55066359-55215113 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 46.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026723, HPA028428, HPA067124" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA026723: AB_10599851, HPA028428: AB_10600991, HPA067124: " "unprognostic (2.28e-1)" "unprognostic (9.81e-3)" "unprognostic (4.70e-3)" "unprognostic (4.86e-3)" "unprognostic (9.31e-3)" "unprognostic (4.84e-3)" "prognostic unfavourable (1.34e-7)" "unprognostic (2.04e-1)" "unprognostic (6.93e-2)" "unprognostic (2.98e-1)" "unprognostic (5.08e-2)" "unprognostic (1.86e-1)" "unprognostic (8.12e-2)" "unprognostic (1.79e-1)" "unprognostic (6.42e-2)" "unprognostic (4.12e-2)" "unprognostic (1.64e-1)" 12.3 7.6 7.5 12.1 8.8 30.1 10.6 20.1 8.5 7.8 10.2 6.8 10.6 5.0 10.1 7.0 7.7 6.9 7.0 14.7 7.9 6.4 10.4 9.3 7.6 12.7 8.0 5.6 10.9 7.3 15.5 16.9 5.8 6.9 7.6 8.5 5.1 9.7 10.7 46.0 8.9 8.7 7.3 6.2 10.9 7.8 4.9 8.7 16.4 7.4 11.5 12.7 9.7 13.7 6.0 10.5 5.9 2.2 3.8 4.5 1.1 17.8 9.8 12.3 6.7 16.1 14.1 14.2 7.9 10.0 11.4 11.9 14.0 6.3 14.3 8.8 14.6 14.5 16.3 13.3 17.9 15.0 9.9 28.7 21.5 16.3 9.6 19.7 22.3 12.3 11.9 17.3 19.7 10.3 26.4 6.0 15.2 4.2 11.9 10.5 18.1 11.9 12.3 15.7 6.2 19.8 12.1 10.9 7.6 13.5 9.7 11.8 6.7 9.8 13.9 10.4 10.1 12.5 12.6 7.6 5.7 18.8 9.9 16.5 9.3 5.9 2.0 2.5 4.5 1.8 2.8 4.8 3.5 3.5 1.8 6.0 3.2 4.2 2.3 3.8 2.2 10.5 1.9 1.1 7.5 8.8 20.1 8.5 7.9 6.4 8.0 5.6 6.9 8.7 USP25 USP21 ENSG00000155313 "Ubiquitin specific peptidase 25" Q9UHP3 21 15730025-15880069 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018297, HPA024142" Approved Supported Cytosol Cytosol "HPA018297: AB_1858672, HPA024142: AB_1858673" "unprognostic (6.35e-2)" "unprognostic (1.50e-1)" "unprognostic (6.90e-2)" "unprognostic (6.29e-2)" "unprognostic (1.39e-1)" "unprognostic (2.88e-2)" "unprognostic (3.91e-2)" "unprognostic (1.65e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (2.33e-2)" "unprognostic (1.40e-1)" "unprognostic (8.24e-3)" "unprognostic (2.34e-3)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.32e-2)" 14.9 8.5 11.0 14.2 15.5 12.4 28.7 11.3 11.1 17.5 11.8 6.6 17.8 6.5 20.7 14.5 12.6 10.6 10.1 17.8 9.9 5.8 12.9 10.4 22.1 14.8 7.6 7.1 14.5 8.2 8.1 8.4 17.7 7.7 12.9 8.6 7.8 11.4 13.6 56.3 8.3 12.3 19.2 7.3 11.6 9.0 26.1 7.5 16.5 10.5 14.6 9.6 13.8 18.1 3.1 2.8 5.8 2.9 2.3 7.2 1.6 13.0 9.9 9.4 1.4 17.3 25.9 11.0 9.4 9.4 7.0 8.9 8.6 7.5 14.1 13.9 14.8 7.0 7.2 12.4 9.7 14.0 8.2 11.5 10.5 6.6 28.8 15.2 5.3 16.8 15.2 11.3 32.7 24.5 14.8 26.6 12.6 5.4 17.3 2.9 11.5 8.8 13.2 8.7 10.7 19.0 3.5 2.0 5.6 13.4 11.4 8.7 6.1 8.9 23.3 10.9 7.1 11.4 5.2 7.8 4.7 11.2 7.1 6.8 8.0 0.0 2.9 3.6 4.0 2.8 4.4 3.1 3.4 7.2 2.5 2.2 3.2 4.8 5.8 2.3 2.5 2.8 4.4 1.6 11.0 15.5 11.3 11.1 9.9 5.8 7.6 7.1 7.7 7.5 USP27X USP27 ENSG00000273820 "Ubiquitin specific peptidase 27, X-linked" A6NNY8 X 49879948-49882565 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077264 Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA077264: " "unprognostic (4.12e-2)" "unprognostic (9.58e-3)" "unprognostic (2.29e-1)" "unprognostic (4.66e-2)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "prognostic unfavourable (6.14e-4)" "unprognostic (3.10e-3)" "unprognostic (3.91e-2)" "unprognostic (1.31e-2)" "prognostic favourable (9.31e-4)" "unprognostic (5.37e-2)" "unprognostic (7.45e-3)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.58e-1)" 1.8 3.3 1.8 5.9 2.9 0.3 7.7 1.7 7.4 3.9 5.9 4.8 2.2 1.1 12.7 4.1 3.1 4.7 3.8 3.9 2.2 3.5 3.5 6.1 1.9 1.3 3.2 8.8 3.2 4.1 0.8 15.5 2.8 4.1 1.7 4.1 5.2 3.9 7.5 2.6 4.7 3.9 1.3 2.0 1.9 3.8 1.9 2.8 3.2 3.6 2.2 3.7 3.1 1.7 1.0 0.7 0.7 0.3 1.3 0.4 2.1 5.6 6.5 7.5 6.2 5.0 5.4 2.4 4.1 2.8 2.3 10.0 2.5 1.4 2.3 6.4 3.6 9.3 6.2 4.1 2.9 4.3 2.3 1.6 9.2 4.2 0.7 5.1 7.0 4.2 4.0 4.0 3.9 4.6 2.4 4.5 5.3 3.5 2.0 7.0 3.9 3.7 5.6 0.5 4.6 2.1 1.7 4.9 4.8 4.5 5.8 5.2 1.7 2.9 3.3 6.4 5.7 0.9 2.2 0.5 1.0 3.8 2.0 3.6 0.7 0.4 0.1 0.6 0.4 0.8 0.6 0.5 0.3 1.0 1.7 0.8 0.6 0.7 0.3 0.7 0.4 1.3 0.4 USP28 KIAA1515 ENSG00000048028 "Ubiquitin specific peptidase 28" Q96RU2 11 113797874-113875570 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 40.1;skeletal muscle: 50.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006778, HPA006779" Enhanced Supported "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA006778: AB_1080520, HPA006779: AB_1080517" "unprognostic (2.54e-1)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" "unprognostic (3.72e-2)" "unprognostic (5.51e-2)" "unprognostic (2.30e-1)" "unprognostic (9.73e-3)" "unprognostic (3.00e-1)" "unprognostic (2.04e-3)" "unprognostic (1.82e-3)" "unprognostic (3.17e-2)" "unprognostic (1.19e-1)" "unprognostic (5.11e-2)" "unprognostic (2.06e-2)" "unprognostic (9.03e-2)" "unprognostic (1.35e-3)" "unprognostic (5.03e-2)" 3.9 3.4 4.8 8.6 5.7 2.4 5.7 26.4 8.6 11.6 5.1 4.9 14.0 4.7 6.0 6.0 5.7 5.0 4.0 40.1 5.0 4.8 5.1 5.6 5.1 7.2 6.8 4.5 7.5 4.1 10.6 9.7 3.9 4.8 8.9 6.0 5.7 5.7 12.2 50.2 3.5 5.1 11.6 6.4 6.9 4.4 5.5 3.8 3.6 5.1 10.1 7.7 7.1 4.6 10.3 4.1 2.1 3.7 17.9 16.2 6.0 10.3 11.6 15.7 20.7 12.8 12.7 11.1 7.6 10.5 10.3 17.7 17.1 14.9 13.7 17.4 10.3 20.3 22.1 14.3 14.4 15.3 10.0 7.3 8.1 9.2 7.9 9.4 7.3 7.6 10.9 11.9 14.2 18.6 12.6 8.9 10.8 5.2 7.1 15.3 18.8 8.4 17.6 21.8 16.6 11.4 10.2 6.9 7.4 18.1 6.2 5.9 15.1 3.3 9.8 11.5 17.2 10.4 7.8 6.1 8.7 11.6 1.1 18.3 7.4 0.1 3.2 2.1 16.2 2.4 8.4 10.3 4.1 11.4 4.1 8.4 2.7 9.4 0.9 17.9 3.7 1.2 5.6 6.0 4.8 5.7 26.4 8.6 5.0 4.8 6.8 4.5 4.8 3.8 USP29 ENSG00000131864 "Ubiquitin specific peptidase 29" Q9HBJ7 19 57119138-57131926 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "blood: 4.1;bone marrow: 2.7;pancreas: 2.1;skin 1: 2.3;testis: 8.4" "Cell line enhanced" "Detected in some" "BEWO: 3.3;HEK 293: 3.2" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA076515 Enhanced "HPA076515: " "unprognostic (1.32e-1)" 0.1 0.1 0.2 0.0 0.2 2.7 0.1 0.1 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.3 0.2 0.1 0.1 0.1 0.3 0.1 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.7 0.0 0.2 2.3 0.1 0.0 0.1 0.1 0.4 8.4 0.4 0.0 0.7 0.1 1.1 1.9 4.1 1.1 1.2 0.8 0.6 0.1 0.7 0.8 0.3 0.0 0.0 3.3 0.0 0.0 0.1 0.1 1.7 0.0 0.9 0.0 0.0 2.0 0.0 0.0 0.0 1.0 3.2 0.8 0.0 0.0 1.1 0.0 1.9 0.9 1.0 1.4 0.0 0.0 0.3 0.9 0.0 0.7 0.0 1.2 0.0 1.0 0.9 0.0 1.0 0.0 2.1 2.0 0.7 0.6 0.4 0.2 0.8 1.3 1.5 1.2 0.5 0.0 0.0 1.6 0.5 1.5 0.5 0.8 0.0 3.1 1.1 1.1 0.8 0.7 0.6 0.5 0.7 0.3 0.3 1.1 0.7 0.7 4.1 1.2 0.4 1.9 0.5 0.6 USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 33.4" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053275, HPA060513, HPA077975" Supported Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA053275: , HPA060513: , HPA077975: " "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (7.88e-2)" "unprognostic (3.33e-2)" "unprognostic (2.16e-2)" "unprognostic (6.03e-2)" "unprognostic (6.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.62e-2)" "unprognostic (2.36e-1)" "unprognostic (3.54e-2)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.61e-2)" "unprognostic (2.78e-1)" "unprognostic (6.21e-2)" "prognostic favourable (1.38e-4)" 16.0 9.0 5.9 20.4 6.5 38.6 21.3 33.4 6.6 12.7 19.1 6.0 16.8 16.2 18.1 13.3 13.6 10.4 14.2 7.6 6.6 4.4 12.9 10.8 17.5 28.2 8.1 3.9 19.5 27.1 7.1 8.2 10.2 7.9 12.4 11.5 8.2 18.5 14.8 12.4 15.9 19.0 16.1 8.0 23.6 14.7 10.3 7.8 22.7 12.5 11.4 22.5 21.3 17.9 11.4 20.6 52.6 28.1 7.2 12.9 13.4 9.2 30.1 15.6 9.7 7.7 12.6 13.7 7.9 9.9 7.7 9.4 11.8 17.3 9.3 12.6 7.8 11.7 14.5 12.3 7.5 15.3 7.8 10.6 10.7 12.7 6.5 6.2 12.8 9.0 16.2 9.3 16.2 16.6 14.0 11.9 4.9 14.3 13.0 10.2 19.7 13.0 19.1 9.4 16.5 9.2 31.6 13.7 10.6 4.9 16.1 9.7 9.7 12.2 15.8 8.9 18.5 5.2 10.5 10.8 19.9 20.8 8.5 17.4 7.3 28.8 28.1 3.5 8.4 22.6 9.3 10.3 11.9 8.6 20.6 11.4 12.9 9.3 52.6 7.2 18.7 4.1 9.1 13.4 5.9 6.5 33.4 6.6 6.6 4.4 8.1 3.9 7.9 7.8 USP30 "FLJ40511, MGC10702" ENSG00000135093 "Ubiquitin specific peptidase 30" Q70CQ3 12 109023089-109088026 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016952 Approved "HPA016952: AB_1858680" "unprognostic (2.34e-1)" "unprognostic (1.57e-2)" "unprognostic (7.04e-2)" "unprognostic (9.91e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (1.91e-1)" "unprognostic (3.60e-3)" "unprognostic (1.98e-1)" "unprognostic (4.96e-2)" "unprognostic (5.07e-2)" "unprognostic (1.07e-1)" "prognostic favourable (5.23e-6)" "unprognostic (2.49e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-3)" 11.7 18.9 12.7 9.0 17.6 12.2 10.4 11.9 21.0 10.3 13.2 29.2 13.6 14.9 12.4 8.5 9.2 11.1 8.4 9.0 10.3 10.6 12.4 21.7 8.9 10.4 16.6 7.8 17.5 12.4 14.7 13.0 6.7 16.0 9.4 11.3 16.4 10.1 12.4 16.4 13.6 14.1 8.6 14.3 9.8 8.5 21.3 16.3 8.7 11.1 5.3 7.1 10.8 8.1 14.2 12.2 12.7 11.0 18.3 17.4 6.0 4.7 3.6 9.7 8.3 6.8 7.8 5.4 5.3 6.9 6.2 5.5 4.3 3.6 11.9 4.5 5.2 5.3 8.4 5.5 7.1 13.8 10.6 3.8 3.3 6.1 7.3 7.6 4.3 9.4 6.7 5.5 5.4 7.1 5.7 5.8 5.2 5.5 11.9 4.3 3.0 10.2 12.9 6.9 7.2 5.0 5.7 8.8 7.9 7.2 5.4 5.6 13.4 5.9 5.1 5.7 3.1 5.5 3.5 14.6 12.1 17.9 6.1 4.6 6.3 9.5 7.1 12.7 15.4 11.0 17.4 14.2 12.9 14.3 4.6 14.2 13.7 12.6 4.2 18.3 8.8 12.2 11.2 6.0 12.7 17.6 11.9 21.0 10.3 10.6 16.6 7.8 16.0 16.3 USP31 KIAA1203 ENSG00000103404 "Ubiquitin specific peptidase 31" Q70CQ4 16 23061406-23149270 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006937 Uncertain Approved Cytosol Cytosol "HPA006937: AB_1080523" "unprognostic (6.45e-2)" "unprognostic (2.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.52e-1)" "unprognostic (6.15e-2)" "unprognostic (2.01e-1)" "prognostic unfavourable (4.41e-5)" "unprognostic (5.59e-2)" "unprognostic (3.75e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-3)" 6.3 5.3 11.2 4.0 16.6 7.1 8.7 12.7 16.5 10.9 4.9 19.7 2.6 3.7 15.3 7.7 9.3 6.5 4.1 11.0 9.0 6.3 6.2 7.7 7.3 3.6 24.6 8.1 3.7 6.3 20.6 10.4 7.4 17.4 9.6 4.9 2.8 6.0 8.5 10.9 15.9 3.4 14.2 14.8 2.8 3.5 20.7 19.3 1.7 4.2 2.4 4.9 13.4 9.5 0.5 0.8 0.6 1.3 0.1 2.1 0.2 9.4 10.0 2.9 4.0 5.3 4.1 2.7 3.3 3.0 4.3 5.1 6.3 5.8 3.2 3.5 4.1 12.5 7.1 12.9 7.1 2.3 2.9 1.3 5.8 13.2 6.6 3.3 3.6 3.5 11.2 7.9 18.3 7.6 3.8 9.9 5.8 6.5 1.6 2.7 5.7 3.1 7.9 8.1 6.3 6.4 14.2 7.7 5.0 5.1 10.2 2.9 4.1 7.3 4.4 8.7 6.4 4.4 8.9 3.3 5.4 3.4 6.2 4.4 3.4 0.1 0.7 0.6 0.8 0.3 2.1 0.1 0.7 1.5 0.8 0.5 0.8 0.8 0.1 0.1 1.3 0.2 1.3 0.2 11.2 16.6 12.7 16.5 9.0 6.3 24.6 8.1 17.4 19.3 USP32 "NY-REN-60, USP10" ENSG00000170832 "Ubiquitin specific peptidase 32" Q8NFA0 17 60179094-60422470 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 58.4" "Cell line enhanced" "Detected in all" "MCF7: 60.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 28.4" "Group enriched" "Detected in many" 10 "dendritic cells: 28.4;granulocytes: 13.5" HPA044365 Approved Approved "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA044365: " "unprognostic (4.10e-2)" "unprognostic (3.38e-2)" "unprognostic (3.57e-2)" "prognostic unfavourable (1.50e-4)" "unprognostic (2.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.90e-3)" "unprognostic (2.33e-2)" "unprognostic (2.24e-1)" "unprognostic (3.93e-1)" "unprognostic (6.49e-2)" "unprognostic (2.78e-1)" "unprognostic (2.82e-1)" "unprognostic (1.97e-1)" "unprognostic (7.23e-2)" "unprognostic (8.35e-2)" "unprognostic (4.16e-2)" 9.5 13.9 17.3 10.8 19.5 20.6 10.9 14.6 20.3 8.0 8.5 18.9 7.9 7.2 8.2 5.4 13.1 7.4 9.1 11.1 14.7 12.2 15.5 19.7 12.5 8.6 18.8 14.3 7.4 8.5 17.3 11.4 9.8 19.2 8.7 8.9 11.6 8.2 9.0 23.0 12.2 7.2 9.8 16.5 12.1 8.1 58.4 18.1 7.3 15.6 7.9 8.5 8.8 8.5 1.4 28.4 13.5 2.1 0.6 1.1 0.9 10.9 12.5 6.6 10.6 16.8 15.8 6.3 9.0 13.5 11.7 15.1 6.5 7.1 6.8 7.5 16.5 5.8 11.3 12.4 20.7 5.1 5.0 13.5 9.9 7.1 16.8 10.7 12.4 14.8 9.1 15.8 14.6 12.8 13.7 5.6 14.5 60.4 10.8 7.6 7.8 6.0 5.2 17.6 4.1 12.3 8.0 4.7 7.0 7.4 2.2 11.5 9.2 14.9 10.8 17.9 18.7 11.2 8.3 5.8 11.0 6.3 8.9 8.4 11.6 4.3 2.1 7.2 1.0 1.8 0.7 1.4 0.7 0.8 4.1 1.1 0.5 1.0 13.5 0.6 2.0 28.4 1.1 0.9 17.3 19.5 14.6 20.3 14.7 12.2 18.8 14.3 19.2 18.1 USP33 "KIAA1097, VDU1" ENSG00000077254 "Ubiquitin specific peptidase 33" Q8TEY7 1 77695987-77759852 "Enzymes, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005719 Uncertain Supported "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA005719: AB_10601708" "unprognostic (2.31e-3)" "unprognostic (2.73e-2)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (9.19e-3)" "unprognostic (1.88e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-1)" "unprognostic (2.67e-1)" "unprognostic (3.59e-1)" "unprognostic (5.36e-3)" "unprognostic (4.89e-2)" "unprognostic (5.76e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-2)" 30.8 27.1 28.1 18.8 32.1 24.6 28.6 55.3 37.5 21.6 20.4 20.6 18.5 20.2 23.3 23.0 17.8 19.2 21.7 17.0 30.7 30.6 26.0 20.3 21.0 20.7 26.0 25.4 25.3 17.0 28.8 23.4 34.6 38.7 24.6 21.0 21.4 19.5 19.8 16.3 19.4 23.8 19.8 21.4 22.3 19.5 19.9 21.6 27.8 25.1 12.9 20.3 21.0 20.0 15.7 12.2 33.2 18.4 12.3 17.8 10.6 16.3 7.5 25.9 17.9 37.3 32.6 22.3 17.9 17.1 21.9 24.6 9.9 14.1 12.2 17.0 17.4 12.9 18.8 12.3 26.8 11.2 14.7 43.1 18.3 8.6 23.2 14.7 10.9 24.0 9.7 21.1 15.5 19.4 16.8 10.7 16.4 6.3 13.2 14.7 25.0 14.8 12.8 27.3 8.6 20.6 16.8 21.8 16.8 12.5 16.7 25.0 9.3 16.0 16.2 20.2 14.4 20.3 16.9 8.7 11.1 11.9 15.3 17.4 10.2 33.2 15.4 20.0 15.1 15.0 15.3 13.4 14.7 15.2 11.5 15.7 17.8 15.6 20.9 12.3 18.4 12.2 13.2 10.6 28.1 32.1 55.3 37.5 30.7 30.6 26.0 25.4 38.7 21.6 USP34 "KIAA0570, KIAA0729" ENSG00000115464 "Ubiquitin specific peptidase 34" Q70CQ2 2 61187463-61470769 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025815, HPA070764" Uncertain Approved Nucleoplasm Nucleoplasm "HPA025815: AB_1858681, HPA070764: " "unprognostic (4.04e-2)" "unprognostic (8.21e-3)" "unprognostic (5.08e-2)" "unprognostic (3.14e-2)" "unprognostic (4.13e-2)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (8.91e-2)" "unprognostic (4.62e-2)" "unprognostic (9.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (6.34e-2)" "unprognostic (7.01e-2)" 17.2 19.6 31.8 37.2 25.6 24.8 28.3 77.1 35.5 22.5 22.7 14.4 31.1 11.4 22.2 44.5 18.6 17.5 20.0 16.9 30.5 24.0 20.5 21.5 29.7 34.2 22.0 21.2 24.7 17.2 33.5 40.3 13.4 22.0 22.7 21.5 21.2 16.9 45.2 27.0 31.6 21.0 22.7 20.8 24.8 19.3 26.4 25.3 21.7 23.2 13.9 33.5 19.1 16.7 6.0 5.8 3.4 4.6 5.2 7.5 2.3 16.6 11.9 15.5 16.0 29.5 19.8 13.0 10.3 14.5 9.2 8.8 16.7 6.4 39.5 10.9 22.1 9.1 12.2 13.5 17.2 14.1 9.6 23.9 11.6 26.8 24.8 17.7 15.2 21.6 17.5 16.7 25.1 19.3 16.3 12.8 20.4 15.6 11.6 25.8 10.5 9.4 12.5 18.9 10.5 27.1 20.4 12.8 13.7 16.2 12.0 17.7 6.3 12.9 17.2 14.6 19.4 8.6 13.4 14.9 7.3 41.5 13.7 16.5 12.5 3.4 2.0 2.8 7.5 2.2 6.7 5.1 5.1 5.5 1.8 6.0 5.8 7.5 3.4 5.2 4.6 5.8 4.5 2.3 31.8 25.6 77.1 35.5 30.5 24.0 22.0 21.2 22.0 25.3 USP35 KIAA1372 ENSG00000118369 "Ubiquitin specific peptidase 35" Q9P2H5 11 78188812-78214711 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 32.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "eosinophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055213, HPA058592" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA055213: , HPA058592: " "unprognostic (6.69e-2)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (6.87e-3)" "unprognostic (3.38e-2)" "unprognostic (1.08e-2)" "unprognostic (2.00e-1)" "unprognostic (1.46e-1)" "unprognostic (3.57e-2)" "unprognostic (3.84e-3)" "unprognostic (1.03e-2)" "unprognostic (3.11e-2)" "unprognostic (1.29e-3)" "unprognostic (2.93e-1)" "unprognostic (1.31e-1)" "unprognostic (4.38e-2)" "unprognostic (1.49e-2)" 4.9 17.1 5.1 5.4 9.3 3.8 5.2 10.4 15.0 6.4 5.8 8.0 6.3 5.5 6.8 5.4 5.6 5.4 5.6 8.7 6.1 6.7 5.0 13.8 5.6 4.8 6.7 8.8 6.6 6.4 32.4 12.0 7.1 15.0 5.0 3.4 7.7 4.0 5.6 5.6 3.2 5.3 7.8 4.5 4.6 3.9 5.3 4.0 1.9 7.7 2.9 4.1 5.2 6.6 0.0 0.1 3.4 0.6 0.1 0.3 0.2 2.1 3.3 5.7 6.0 9.8 9.0 3.9 4.9 5.8 5.8 4.1 8.3 4.6 1.7 5.1 9.2 5.7 3.8 7.6 3.4 12.2 2.0 2.8 8.6 4.8 7.6 1.8 8.3 7.6 5.1 12.1 3.5 7.1 3.9 4.2 4.5 1.9 4.6 7.2 1.7 5.3 2.8 5.3 2.1 4.6 3.9 2.8 5.4 3.8 5.0 1.8 4.2 1.5 8.6 10.7 6.1 12.6 2.6 5.7 1.9 2.6 3.2 1.9 6.2 0.0 0.2 3.4 0.1 0.6 0.0 0.0 0.2 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.1 0.1 0.1 0.2 5.1 9.3 10.4 15.0 6.1 6.7 6.7 8.8 15.0 4.0 USP36 "FLJ12851, KIAA1453" ENSG00000055483 "Ubiquitin specific peptidase 36" Q9P275 17 78787381-78841441 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012082, HPA012395, HPA052860" Uncertain Supported Enhanced "Nucleoli,Nuclear speckles" Nucleoli "Nuclear speckles" "HPA012082: AB_1858682, HPA012395: , HPA052860: " "unprognostic (1.94e-2)" "unprognostic (2.80e-2)" "unprognostic (1.07e-1)" "prognostic unfavourable (5.18e-5)" "unprognostic (9.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.50e-3)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" 26.3 23.4 12.9 21.3 16.0 36.5 28.1 28.3 17.4 17.2 16.4 25.4 19.2 12.3 25.1 22.2 14.6 18.0 21.9 17.4 10.4 11.2 15.9 16.4 20.0 17.2 17.5 16.0 41.3 33.6 19.6 30.0 23.4 14.6 21.0 15.1 20.4 21.8 45.5 19.5 29.3 15.1 25.2 14.5 18.2 17.3 20.8 13.7 12.8 19.3 11.2 22.2 24.6 18.1 6.7 12.4 8.9 5.3 5.6 8.8 2.5 15.7 19.1 5.6 10.4 12.1 13.5 10.8 13.0 13.2 12.5 8.4 18.5 8.0 20.2 6.6 11.5 11.6 13.2 9.6 22.4 4.8 20.0 18.4 27.8 19.2 12.4 20.1 10.1 11.7 16.0 17.8 39.9 10.8 14.6 21.3 10.3 12.1 18.3 20.4 8.7 15.3 14.1 12.3 13.5 7.9 16.6 16.6 10.1 9.3 43.5 23.6 11.2 12.8 9.2 29.5 13.7 17.1 22.9 15.8 6.2 24.8 11.6 15.8 9.2 8.9 3.9 3.1 7.6 5.3 8.8 6.4 7.2 6.4 2.3 6.7 8.0 7.7 5.7 5.6 3.3 12.4 4.8 2.5 12.9 16.0 28.3 17.4 10.4 11.2 17.5 16.0 14.6 13.7 USP37 KIAA1594 ENSG00000135913 "Ubiquitin specific peptidase 37" Q86T82 2 218450251-218568361 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045160 Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA045160: AB_10795620" "unprognostic (7.00e-2)" "unprognostic (2.29e-1)" "unprognostic (8.83e-2)" "unprognostic (9.19e-4)" "unprognostic (1.83e-1)" "prognostic favourable (2.85e-4)" "unprognostic (2.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.66e-3)" "unprognostic (1.17e-1)" "unprognostic (3.78e-3)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.87e-1)" "unprognostic (6.69e-2)" "unprognostic (6.41e-3)" 10.4 8.4 9.2 9.7 10.5 19.2 9.0 16.2 10.0 8.3 6.6 10.4 8.0 5.8 9.6 15.8 8.2 7.8 7.0 6.9 7.4 5.5 6.1 7.4 8.1 10.5 8.7 7.8 15.3 6.9 10.7 17.1 8.5 8.7 7.3 7.0 7.4 9.7 9.6 11.1 9.9 7.2 8.1 10.2 7.0 6.6 22.2 10.5 13.4 9.8 5.4 9.4 10.5 9.1 7.4 6.1 7.4 4.8 5.9 9.0 2.5 7.3 5.4 11.4 8.8 3.0 3.7 9.7 5.6 4.1 9.9 11.1 10.2 5.9 6.7 6.2 4.4 7.1 12.5 6.3 10.9 9.2 6.6 18.2 10.9 6.7 3.4 11.8 9.1 2.0 3.8 10.3 7.5 4.2 13.1 13.0 6.2 5.5 15.2 8.1 9.8 4.7 12.3 17.1 6.2 3.4 8.8 12.5 6.8 9.0 4.5 5.7 5.2 8.4 5.3 11.1 9.8 6.2 7.4 8.9 7.8 13.8 6.0 8.8 7.5 6.5 4.2 7.4 7.0 4.8 7.3 5.4 5.8 5.9 4.4 7.4 9.0 5.7 3.5 5.9 4.4 6.1 7.3 2.5 9.2 10.5 16.2 10.0 7.4 5.5 8.7 7.8 8.7 10.5 USP38 "HP43.8KD, KIAA1891" ENSG00000170185 "Ubiquitin specific peptidase 38" Q8NB14 4 143184917-143223830 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 45.3" "Cell line enhanced" "Detected in all" "U-266/84: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036990, HPA047948" Uncertain Approved Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA036990: , HPA047948: AB_2680220" "unprognostic (5.01e-2)" "unprognostic (2.45e-1)" "unprognostic (2.04e-3)" "unprognostic (2.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.61e-2)" "unprognostic (1.67e-1)" "unprognostic (7.49e-2)" "unprognostic (3.66e-2)" "unprognostic (3.97e-2)" "unprognostic (8.03e-2)" "unprognostic (7.72e-3)" "prognostic favourable (1.20e-4)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" 7.7 7.8 6.6 6.6 6.5 19.1 8.3 7.4 7.8 7.9 12.1 8.6 8.8 8.8 8.3 7.1 8.6 7.1 7.6 12.5 6.6 5.3 9.3 15.2 12.7 11.1 10.3 5.1 6.3 8.8 10.0 6.2 11.4 5.9 6.6 6.6 7.1 7.2 7.0 45.3 8.9 13.2 6.5 10.8 10.6 7.4 7.5 8.2 22.6 8.6 10.2 8.4 7.8 8.8 6.3 8.1 12.5 5.7 12.3 9.9 5.0 4.7 4.5 4.0 6.8 5.2 5.2 2.9 7.6 7.4 7.0 6.0 12.9 7.0 5.9 5.4 6.4 3.8 9.3 7.5 5.8 14.4 6.0 5.4 5.3 2.7 7.2 10.9 5.4 6.3 6.9 7.2 5.8 7.0 11.7 18.5 4.7 7.5 14.2 2.0 3.6 8.7 9.4 5.9 5.6 4.5 5.5 8.1 7.3 5.9 10.3 6.6 6.3 4.1 8.3 6.5 5.3 5.6 7.9 20.7 35.1 10.7 6.6 8.4 5.4 12.5 5.4 11.7 7.5 5.7 9.6 6.3 6.6 6.5 8.1 5.7 6.7 5.7 5.4 12.3 5.7 3.5 9.9 5.0 6.6 6.5 7.4 7.7 6.6 5.3 10.3 5.1 5.9 8.2 USP39 "CGI-21, SAD1, SNRNP65" ENSG00000168883 "Ubiquitin specific peptidase 39" Q53GS9 2 85602856-85649282 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034823, HPA077350" Supported Supported Supported Nucleoplasm Nucleoplasm "HPA034823: AB_10602488, HPA077350: " "unprognostic (1.10e-2)" "unprognostic (3.31e-3)" "unprognostic (1.83e-1)" "prognostic unfavourable (5.52e-4)" "unprognostic (8.46e-3)" "unprognostic (3.67e-2)" "prognostic unfavourable (2.84e-6)" "unprognostic (1.10e-2)" "unprognostic (1.69e-1)" "unprognostic (1.89e-1)" "unprognostic (5.17e-3)" "unprognostic (3.14e-2)" "prognostic unfavourable (4.05e-7)" "unprognostic (3.95e-3)" "unprognostic (2.25e-1)" "unprognostic (2.52e-2)" "unprognostic (2.52e-1)" 19.0 15.1 14.5 23.5 16.8 30.4 18.3 14.9 20.8 20.2 24.1 18.7 11.8 14.7 22.1 24.1 20.7 16.8 20.6 25.5 13.7 13.7 17.8 20.8 18.5 20.8 15.2 14.5 19.2 15.0 17.7 13.7 28.0 15.8 21.6 20.5 18.0 17.2 20.0 44.2 20.2 17.8 19.0 15.0 21.0 18.1 17.2 13.0 56.5 24.7 23.9 27.0 23.0 26.0 25.3 28.8 29.8 29.7 26.4 37.3 28.2 21.7 22.2 22.7 24.9 16.5 13.0 25.5 18.4 17.4 27.4 24.5 35.4 15.8 25.8 17.4 17.3 15.7 43.4 19.8 34.9 25.9 27.6 32.0 13.3 31.2 16.3 38.8 21.9 9.1 15.9 21.1 19.0 21.8 39.2 15.2 20.1 25.3 38.2 29.2 30.0 20.6 35.3 48.7 19.5 14.7 17.0 20.9 17.0 11.5 18.9 15.8 12.7 19.0 13.9 17.0 21.2 20.2 30.4 13.5 24.9 27.6 14.5 41.0 20.3 28.0 25.5 29.8 30.3 29.7 35.2 24.3 31.8 31.2 28.8 25.3 31.4 28.5 16.4 26.4 26.9 22.5 37.3 28.2 14.5 16.8 14.9 20.8 13.7 13.7 15.2 14.5 15.8 13.0 USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277831-49340712 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018499 Approved Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA018499: AB_1858689" "unprognostic (2.34e-3)" "unprognostic (1.52e-1)" "unprognostic (2.22e-3)" "unprognostic (6.12e-2)" "unprognostic (3.51e-1)" "unprognostic (4.33e-2)" "unprognostic (9.42e-2)" "prognostic favourable (4.46e-5)" "unprognostic (3.54e-1)" "unprognostic (9.07e-3)" "unprognostic (2.78e-2)" "unprognostic (1.70e-3)" "prognostic favourable (4.29e-5)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 22.1 18.4 21.4 22.4 29.3 41.4 23.1 30.3 32.5 20.7 20.1 26.8 16.9 16.1 23.6 20.9 23.5 19.3 17.5 22.8 22.2 18.0 20.2 18.5 25.7 25.5 20.2 17.5 23.6 17.1 23.6 19.7 22.1 24.3 20.9 21.9 23.6 19.1 21.3 25.7 27.6 19.4 25.9 20.4 30.6 17.7 25.0 19.7 36.8 21.2 14.1 42.4 22.1 22.0 17.0 24.1 59.4 27.3 21.5 18.6 22.2 6.2 7.2 10.1 13.4 18.7 20.1 6.8 17.2 15.3 22.3 20.1 7.7 15.9 12.2 6.8 25.0 8.5 13.4 24.4 20.8 18.8 4.0 27.0 14.4 8.5 27.4 14.2 15.6 20.6 10.7 24.4 20.1 25.7 9.4 19.4 20.6 10.7 16.8 24.2 8.5 12.7 6.9 6.3 10.6 17.5 13.1 8.4 11.2 12.5 8.8 6.3 6.1 22.9 22.8 15.0 8.2 18.7 10.0 15.5 7.5 17.8 13.5 22.6 17.2 18.0 27.3 30.0 16.9 22.1 18.6 17.0 17.6 16.9 24.1 14.1 17.1 15.0 59.4 21.5 24.4 9.6 18.6 22.2 21.4 29.3 30.3 32.5 22.2 18.0 20.2 17.5 24.3 19.7 USP40 FLJ10785 ENSG00000085982 "Ubiquitin specific peptidase 40" Q9NVE5 2 233475520-233566782 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005821 Uncertain Approved Vesicles Vesicles "HPA005821: AB_1080526" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" "unprognostic (3.70e-1)" "unprognostic (2.15e-1)" "unprognostic (5.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (4.09e-2)" "unprognostic (1.90e-2)" "unprognostic (2.53e-2)" 12.5 20.5 11.0 8.2 17.7 3.5 16.1 8.2 13.5 12.4 12.1 26.1 22.5 11.6 16.2 28.1 13.9 13.4 13.2 10.8 11.3 8.5 16.9 15.7 13.9 7.6 22.1 10.1 19.6 17.2 22.8 24.3 16.3 16.5 16.1 11.2 16.4 13.9 19.7 13.6 21.7 15.2 17.1 20.1 11.4 16.3 23.3 18.9 9.8 21.2 9.4 12.0 18.0 11.8 1.9 5.0 0.4 2.8 1.4 2.2 1.4 9.6 11.3 10.4 7.0 15.3 14.3 9.1 9.6 7.4 8.9 9.7 8.0 11.6 0.2 2.8 15.4 17.3 7.9 17.0 12.8 0.0 5.1 7.7 9.3 13.6 13.3 3.2 5.2 13.6 12.3 13.1 18.5 10.2 12.3 1.9 12.5 7.8 3.4 4.7 4.6 9.2 0.0 21.5 4.5 10.6 15.7 5.7 6.2 7.6 7.9 9.8 9.0 7.2 10.1 12.5 7.8 5.2 11.5 3.5 2.6 0.4 16.1 5.8 10.7 0.0 2.7 0.0 1.3 2.8 0.6 1.3 1.5 1.3 4.0 1.9 1.9 2.2 0.4 1.4 2.3 5.0 2.0 1.4 11.0 17.7 8.2 13.5 11.3 8.5 22.1 10.1 16.5 18.9 USP42 FLJ12697 ENSG00000106346 "Ubiquitin specific peptidase 42" Q9H9J4 7 6104884-6161564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064800 Approved Nucleoplasm Nucleoplasm "HPA064800: " "unprognostic (1.48e-2)" "unprognostic (1.47e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-1)" "unprognostic (1.19e-2)" "unprognostic (3.32e-1)" "unprognostic (1.05e-1)" "unprognostic (2.82e-1)" "unprognostic (6.21e-3)" "unprognostic (2.47e-2)" "unprognostic (3.17e-3)" "unprognostic (3.14e-2)" "unprognostic (3.06e-2)" "unprognostic (2.19e-2)" "unprognostic (2.66e-1)" 6.7 5.6 5.7 5.7 9.5 19.8 7.2 14.1 10.6 8.5 7.4 10.4 5.5 8.1 14.1 7.0 6.9 8.1 6.5 5.4 5.8 6.0 7.4 7.1 7.3 6.5 6.7 4.9 10.6 11.7 10.5 10.9 8.2 6.2 7.4 6.5 8.9 6.6 6.3 7.4 9.2 9.2 8.7 9.9 7.8 6.7 25.2 8.1 14.3 7.7 6.2 8.3 7.6 6.9 1.9 2.2 3.3 2.4 1.9 4.3 0.8 8.3 6.2 11.3 11.0 6.5 5.0 7.7 4.5 5.8 5.4 5.3 4.4 4.4 9.9 3.0 5.6 7.8 9.4 5.0 5.8 2.4 7.3 4.6 5.3 4.5 5.5 10.6 5.3 5.8 5.9 5.7 7.4 6.5 17.6 6.7 3.5 7.4 6.4 12.0 12.7 4.8 12.2 8.8 6.8 5.0 4.4 8.6 15.3 5.8 12.0 3.6 5.5 5.5 5.5 4.8 17.8 6.0 5.4 6.0 5.0 8.6 4.0 6.5 9.4 2.3 1.1 3.3 2.1 2.4 3.0 1.9 2.6 1.3 1.1 1.1 1.7 4.3 1.4 1.9 1.2 2.2 1.8 0.8 5.7 9.5 14.1 10.6 5.8 6.0 6.7 4.9 6.2 8.1 USP43 FLJ30626 ENSG00000154914 "Ubiquitin specific peptidase 43" Q70EL4 17 9644698-9729691 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.6" "Cell line enhanced" "Detected in many" "BEWO: 12.3;SK-BR-3: 8.5;T-47d: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA023389, HPA027762" Uncertain "HPA023389: AB_1858691, HPA027762: AB_10603001" "unprognostic (1.39e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-3)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (2.04e-1)" "unprognostic (6.40e-3)" "unprognostic (2.26e-1)" "unprognostic (3.05e-3)" "unprognostic (2.41e-2)" "unprognostic (7.49e-2)" "unprognostic (5.95e-2)" "prognostic favourable (5.39e-4)" "unprognostic (3.24e-1)" "unprognostic (2.06e-1)" "unprognostic (3.28e-1)" 0.2 0.2 4.2 1.2 3.4 0.9 3.0 0.7 6.0 4.9 10.0 0.6 15.7 6.2 2.9 1.7 6.7 6.3 5.1 0.2 4.1 3.8 3.7 8.7 3.4 0.2 1.7 3.1 1.0 7.7 1.7 3.7 61.6 0.7 10.8 5.0 0.3 11.3 12.4 0.2 2.4 12.5 0.3 1.0 0.2 2.6 2.9 0.2 0.4 1.7 4.2 2.7 1.3 2.1 0.0 0.5 0.0 0.0 1.1 0.1 0.1 5.6 1.4 0.0 0.6 0.0 0.0 12.3 0.1 0.2 0.6 1.7 2.8 4.6 0.0 1.9 0.2 6.9 0.6 5.4 0.6 3.6 1.9 0.3 2.9 1.0 0.1 0.5 0.0 0.0 7.1 0.3 3.0 0.0 0.0 0.0 0.0 2.6 0.9 4.6 0.7 0.3 3.7 0.0 0.8 4.3 3.1 0.7 0.0 2.4 8.5 1.0 10.2 1.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 4.2 3.4 0.7 6.0 4.1 3.8 1.7 3.1 0.7 0.2 USP44 FLJ14528 ENSG00000136014 "Ubiquitin specific peptidase 44" Q9H0E7 12 95516560-95551490 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 26.8" "Cell line enriched" "Detected in some" 5 "NTERA-2: 54.8" "Cancer enhanced" "Detected in some" "testis cancer: 3.0" "Region enriched" "Detected in many" 5 "cerebellum: 10.9" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 8.6" "Group enriched" "Detected in many" 39 "B-cells: 5.6;T-cells: 8.6" "Low region specificity" "Detected in all" HPA026543 Approved "Nucleoli fibrillar center,Microtubules" "Nucleoli fibrillar center, Microtubules" "HPA026543: AB_1858692" "unprognostic (2.12e-2)" "unprognostic (1.14e-1)" "unprognostic (4.68e-2)" "unprognostic (1.01e-3)" "unprognostic (1.83e-4)" "unprognostic (7.18e-4)" "unprognostic (5.55e-2)" "unprognostic (1.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.73e-2)" "unprognostic (6.88e-2)" "unprognostic (2.97e-2)" "unprognostic (8.12e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-1)" "unprognostic (7.41e-2)" "unprognostic (7.07e-2)" 1.3 1.0 0.7 1.2 1.3 0.5 1.4 10.9 2.1 1.7 1.7 1.7 1.4 0.5 3.0 1.0 0.9 1.6 1.1 1.0 0.7 0.6 1.9 0.2 4.7 1.9 1.3 1.2 1.6 3.6 4.8 4.0 0.3 1.8 1.7 0.6 2.3 1.8 2.6 0.4 0.6 1.3 1.2 0.6 1.9 1.0 26.8 1.2 0.8 1.7 0.0 1.6 1.1 2.3 5.6 0.1 0.1 0.0 0.1 8.6 1.3 0.0 0.1 4.5 0.0 0.0 0.0 0.1 0.4 1.3 0.5 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.7 0.0 2.2 10.1 0.0 0.0 2.4 4.1 0.2 0.0 0.0 0.3 0.0 0.2 1.6 0.0 0.0 0.0 5.2 0.0 54.8 0.0 0.0 0.0 0.0 0.9 0.3 3.5 2.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.3 0.1 0.0 0.0 0.0 1.5 0.0 3.4 5.6 2.3 2.0 0.0 4.4 8.6 5.5 0.1 0.1 0.0 0.1 0.3 1.3 0.7 1.3 10.9 2.1 0.7 0.6 1.3 1.2 1.8 1.2 USP45 MGC14793 ENSG00000123552 "Ubiquitin specific peptidase 45" Q70EL2 6 99432379-99521728 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029602, HPA029604" Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA029602: AB_10600418, HPA029604: AB_10602283" "unprognostic (7.81e-3)" "unprognostic (3.10e-3)" "unprognostic (1.63e-2)" "unprognostic (6.62e-2)" "unprognostic (1.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.15e-2)" "unprognostic (1.01e-1)" "unprognostic (2.77e-2)" "unprognostic (8.65e-2)" "unprognostic (2.95e-3)" "unprognostic (1.10e-1)" "unprognostic (3.43e-3)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" "unprognostic (1.43e-1)" "unprognostic (6.91e-2)" 9.8 9.1 8.5 10.2 12.2 7.2 9.0 28.4 11.6 9.0 9.7 8.6 8.9 13.7 15.7 9.6 10.0 8.1 11.9 11.5 7.7 8.5 12.2 9.0 7.1 12.7 9.8 8.0 10.7 9.6 10.2 21.7 9.6 15.0 9.9 13.1 7.9 9.8 8.4 14.6 11.8 12.4 10.8 10.6 9.9 8.9 5.7 9.4 7.1 10.7 10.4 9.5 8.8 15.0 8.6 5.1 3.7 2.5 2.6 6.2 1.4 4.1 3.0 5.9 8.3 10.9 10.4 6.2 7.2 8.1 7.6 10.8 6.1 4.6 11.1 5.4 7.3 5.6 9.0 7.2 10.5 8.7 8.6 10.8 5.9 4.8 8.4 10.0 6.2 11.1 5.7 6.8 11.6 11.2 26.0 11.0 7.1 3.9 3.2 9.5 9.5 6.4 4.7 4.4 6.2 10.5 4.9 8.3 6.8 5.1 6.8 5.3 3.6 4.9 11.2 4.2 5.3 6.1 11.0 4.7 4.3 20.3 7.2 9.5 7.4 3.7 2.0 0.6 4.9 1.3 6.2 7.4 4.2 5.6 3.5 8.6 3.0 2.9 0.5 2.6 2.5 5.1 3.5 1.4 8.5 12.2 28.4 11.6 7.7 8.5 9.8 8.0 15.0 9.4 USP46 FLJ12552 ENSG00000109189 "Ubiquitin specific peptidase 46" P62068 4 52590972-52659335 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Behavior, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, CAB076369, CAB076370" Uncertain Approved Nucleoli Nucleoli "CAB076369: , CAB076370: , HPA007288: AB_1080531" "unprognostic (1.15e-2)" "unprognostic (1.64e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (1.31e-1)" "unprognostic (1.41e-1)" "unprognostic (1.53e-3)" "unprognostic (1.59e-1)" "unprognostic (2.45e-2)" "unprognostic (1.80e-2)" "unprognostic (2.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (3.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.28e-1)" 4.7 9.5 26.0 3.5 20.9 2.8 7.0 23.7 29.4 8.9 4.2 12.8 5.2 4.8 7.2 6.2 12.4 7.8 5.8 28.9 21.9 19.0 10.8 3.1 4.4 3.7 19.1 13.9 12.3 5.6 12.2 5.3 10.6 12.7 7.7 4.6 5.3 8.0 7.8 13.7 8.0 4.5 5.5 18.9 3.5 6.3 12.2 15.0 1.0 10.0 4.3 5.8 7.3 5.7 1.4 4.4 2.0 1.4 1.2 3.9 1.0 5.3 3.8 12.3 9.1 13.5 16.9 13.6 8.8 7.1 6.5 5.5 7.6 4.2 3.5 10.4 8.7 3.1 21.4 10.2 12.0 3.1 7.5 5.5 3.6 8.5 13.5 7.3 6.5 14.4 9.6 6.7 6.3 9.6 5.4 5.0 13.8 4.9 3.1 3.8 9.1 4.6 7.9 9.0 0.7 14.0 9.9 7.4 8.9 4.3 14.7 8.5 5.4 5.5 8.9 6.4 14.0 7.5 13.2 5.2 2.4 2.8 9.9 4.4 7.9 2.0 1.4 0.3 2.3 1.2 1.7 1.4 3.9 2.0 2.8 1.2 0.9 0.8 0.3 1.2 0.9 4.4 1.2 1.0 26.0 20.9 23.7 24.3 21.9 19.0 19.1 13.9 12.7 15.0 USP47 ENSG00000170242 "Ubiquitin specific peptidase 47" Q96K76 11 11841423-11959323 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029286, HPA029289" Supported "HPA029286: AB_10599852, HPA029289: AB_10601675" "unprognostic (2.02e-1)" "unprognostic (2.72e-1)" "unprognostic (3.05e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (2.65e-2)" "unprognostic (2.27e-2)" "unprognostic (7.39e-2)" "unprognostic (1.54e-2)" "unprognostic (7.05e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-1)" "unprognostic (1.51e-1)" "unprognostic (9.96e-3)" "unprognostic (1.90e-1)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" 16.6 17.0 17.9 18.5 20.9 20.3 16.9 25.7 19.0 16.4 18.1 16.2 21.3 11.6 18.0 15.0 18.7 13.7 13.5 25.5 18.1 13.4 14.6 25.1 16.6 13.4 21.9 12.9 16.9 19.6 38.8 31.8 23.7 19.3 18.0 14.2 10.2 15.1 19.2 58.1 18.4 15.1 21.3 19.5 13.3 18.1 16.8 23.9 27.9 16.8 12.4 15.2 21.3 19.4 9.7 10.1 14.0 13.2 22.8 19.3 9.7 21.0 12.8 23.1 10.9 16.7 18.4 10.6 24.2 18.3 16.0 18.1 12.6 18.8 23.8 11.5 22.5 14.4 17.8 12.1 24.7 23.2 15.0 14.3 23.8 8.9 14.8 18.5 20.1 17.1 16.7 10.5 23.3 17.8 28.5 20.6 19.5 8.3 16.7 8.2 6.2 10.4 17.2 24.3 7.4 17.2 24.4 8.0 16.4 21.6 15.1 13.4 12.1 13.6 19.6 22.7 13.8 19.3 14.7 6.5 14.9 22.6 15.6 11.4 16.2 13.3 7.7 14.0 15.2 9.5 19.3 9.7 13.8 14.7 10.1 8.6 17.9 15.3 3.6 22.8 13.2 6.1 9.9 9.7 17.9 20.9 25.7 19.0 18.1 13.4 21.9 12.9 19.3 23.9 USP48 "FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31" ENSG00000090686 "Ubiquitin specific peptidase 48" Q86UV5 1 21678298-21783606 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030045, HPA030046" Approved Supported Nucleoplasm,Mitochondria,Cytosol Nucleoplasm "Mitochondria, Cytosol" "HPA030045: AB_10670833, HPA030046: AB_10603325" "unprognostic (1.35e-1)" "unprognostic (3.72e-1)" "unprognostic (5.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.23e-1)" "unprognostic (7.00e-3)" "prognostic unfavourable (6.09e-8)" "unprognostic (1.04e-2)" "unprognostic (3.01e-3)" "unprognostic (9.30e-2)" "unprognostic (7.54e-2)" "unprognostic (4.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-1)" "unprognostic (5.70e-2)" "unprognostic (2.80e-2)" 20.1 38.8 18.6 28.9 30.9 30.9 22.1 48.2 27.5 19.9 18.4 25.6 15.4 17.6 21.3 17.6 19.0 17.4 20.5 17.8 16.9 15.8 15.5 18.3 18.3 26.2 26.6 22.5 27.0 19.8 24.6 35.4 23.1 26.8 21.6 22.0 22.1 24.5 16.3 17.0 23.9 22.2 22.2 19.7 29.1 26.2 15.8 23.6 25.8 23.9 14.0 29.0 19.8 21.0 13.7 10.5 33.7 9.6 5.6 11.2 5.6 14.6 7.0 16.5 11.9 14.3 17.7 16.3 18.5 12.6 12.4 16.5 6.4 15.0 16.5 12.5 16.7 13.6 20.3 14.9 18.9 16.0 13.9 35.3 26.1 11.6 12.8 17.7 18.9 14.3 12.9 12.6 14.1 36.6 27.7 46.8 15.2 7.3 14.6 23.0 10.4 12.6 20.6 16.6 19.3 14.3 12.4 20.1 12.5 17.4 16.0 41.8 8.2 21.4 25.9 13.4 11.1 16.4 10.7 37.5 26.6 16.4 12.9 22.0 19.7 33.7 9.6 16.7 6.4 4.6 7.6 13.7 9.5 9.5 10.5 12.8 11.2 7.0 8.9 5.6 5.0 7.7 10.1 5.6 18.6 30.9 48.2 27.5 16.9 15.8 26.6 22.5 26.8 23.6 USP49 MGC20741 ENSG00000164663 "Ubiquitin specific peptidase 49" Q70CQ1 6 41789896-41895361 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 23.4;U-698: 33.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030254, HPA030255" Uncertain "HPA030254: AB_10600198, HPA030255: AB_10601218" "unprognostic (1.71e-1)" "unprognostic (4.86e-3)" "unprognostic (1.93e-1)" "unprognostic (2.57e-4)" "unprognostic (4.46e-2)" "unprognostic (2.84e-4)" "unprognostic (7.17e-3)" "unprognostic (5.06e-2)" "unprognostic (1.19e-2)" "unprognostic (3.22e-1)" "unprognostic (5.59e-3)" "unprognostic (8.28e-2)" "unprognostic (1.26e-5)" "unprognostic (5.39e-2)" "unprognostic (4.58e-2)" "unprognostic (4.37e-3)" "unprognostic (3.24e-3)" 2.4 2.4 7.6 3.5 6.0 7.3 2.7 12.7 9.3 2.3 1.9 2.0 4.3 2.2 4.0 2.3 1.8 2.2 2.1 3.5 7.6 4.2 1.6 1.7 2.4 3.7 3.0 5.8 4.0 3.2 2.6 4.8 1.8 4.2 2.4 2.1 3.7 2.7 2.4 3.8 4.1 2.2 3.2 3.2 3.5 2.2 7.4 3.2 7.3 7.7 0.6 3.4 2.8 2.0 1.2 0.7 8.5 1.8 0.8 0.9 0.4 3.0 0.9 12.3 6.0 1.5 1.6 5.1 1.1 1.1 1.8 2.2 3.9 0.7 12.4 1.3 1.5 1.3 7.6 1.1 2.7 3.0 5.6 4.4 4.6 1.3 1.0 3.4 2.7 1.6 0.9 2.6 1.7 1.1 9.2 3.4 1.4 1.7 13.1 5.2 3.4 1.1 23.4 6.0 2.7 0.7 2.1 8.3 3.4 1.6 0.6 0.6 1.8 3.1 3.1 4.3 4.2 1.4 1.5 6.4 5.6 33.3 0.5 3.5 0.8 8.5 1.3 1.4 0.8 1.5 0.4 1.2 0.4 0.8 0.5 0.9 0.9 0.7 2.4 0.8 1.8 0.7 0.4 0.4 7.6 6.0 12.7 9.3 7.6 4.2 3.0 5.8 4.2 3.2 USP5 IsoT ENSG00000111667 "Ubiquitin specific peptidase 5" P45974 12 6852128-6866632 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006756 Uncertain Approved Nucleoplasm,Cytosol 820000 "Nucleoplasm, Cytosol" "HPA006756: AB_1080534" "unprognostic (2.19e-1)" "unprognostic (5.83e-2)" "unprognostic (2.48e-1)" "unprognostic (2.57e-1)" "unprognostic (7.60e-2)" "unprognostic (2.21e-2)" "unprognostic (4.02e-2)" "unprognostic (3.93e-2)" "unprognostic (2.57e-1)" "unprognostic (4.71e-2)" "unprognostic (8.90e-3)" "unprognostic (4.69e-2)" "unprognostic (1.17e-2)" "unprognostic (2.65e-2)" "unprognostic (3.56e-1)" "unprognostic (3.23e-1)" "unprognostic (2.02e-3)" 18.6 28.7 23.1 17.8 32.6 13.6 12.9 24.6 50.9 15.9 21.5 26.8 13.8 17.6 22.3 12.8 27.7 19.1 14.7 22.4 23.9 28.6 14.9 24.8 14.4 18.6 23.6 33.2 14.4 13.2 29.7 19.6 21.7 36.8 19.5 16.1 11.6 14.1 22.7 41.2 33.5 18.1 25.3 23.6 14.1 15.9 30.9 18.7 22.8 19.2 20.4 19.9 21.3 16.0 10.8 18.6 5.3 16.6 10.8 17.1 16.6 25.3 39.7 26.7 30.2 18.2 16.8 34.1 27.6 21.2 33.0 24.1 37.5 25.2 30.7 14.5 28.6 22.4 29.3 27.4 21.2 57.5 24.8 28.1 31.9 20.3 14.2 25.4 29.6 16.9 15.9 28.5 19.8 28.2 24.1 12.3 27.2 27.8 38.1 12.6 52.0 16.8 30.0 34.8 21.2 18.8 24.7 14.7 29.7 18.8 28.7 12.0 11.5 20.8 27.3 28.0 33.9 21.3 34.3 14.9 34.2 46.7 31.2 16.2 27.2 2.3 12.3 5.3 17.1 16.6 16.1 10.8 15.2 14.4 18.6 10.0 14.6 14.8 0.9 10.8 14.7 13.6 12.9 16.6 23.1 32.6 24.6 50.9 23.9 28.6 23.6 33.2 36.8 18.7 USP50 ENSG00000170236 "Ubiquitin specific peptidase 50" Q70EL3 15 50500562-50546708 "Enzymes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "testis: 20.2" "Cell line enhanced" "Detected in some" "HaCaT: 1.2;HEL: 1.1;RH-30: 1.0;SK-BR-3: 1.7;SK-MEL-30: 2.9;U-698: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in single" 9 "hippocampal formation: 0.4" "Low region specificity" "Detected in single" HPA039470 Uncertain "HPA039470: AB_10672964" "unprognostic (7.05e-3)" "unprognostic (2.38e-1)" "unprognostic (2.01e-2)" "unprognostic (4.04e-3)" "unprognostic (3.37e-1)" "unprognostic (2.53e-2)" "unprognostic (3.95e-2)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (1.85e-1)" "unprognostic (3.81e-2)" "unprognostic (4.65e-2)" "unprognostic (2.47e-1)" "unprognostic (7.49e-4)" "unprognostic (3.03e-1)" 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.2 1.7 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.6 1.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP51 ENSG00000247746 "Ubiquitin specific peptidase 51" Q70EK9 X 55484616-55489202 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 34.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in some" "eosinophil: 2.4;naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA001942 Uncertain Approved "Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoli fibrillar center" "HPA001942: AB_1080536" "unprognostic (1.19e-2)" "unprognostic (4.65e-2)" "unprognostic (3.67e-2)" "unprognostic (1.02e-3)" "unprognostic (8.08e-2)" "unprognostic (3.26e-1)" "unprognostic (3.17e-3)" "unprognostic (2.07e-3)" "unprognostic (5.69e-2)" "prognostic favourable (5.70e-4)" "unprognostic (1.01e-3)" "unprognostic (1.27e-1)" "prognostic favourable (2.63e-5)" "unprognostic (2.81e-3)" "unprognostic (5.92e-2)" "unprognostic (5.85e-2)" "unprognostic (1.63e-1)" 0.6 2.7 2.0 0.3 2.9 0.1 0.9 2.3 1.8 1.4 0.6 0.0 1.8 34.1 0.2 3.4 0.3 1.0 1.8 3.7 2.2 0.5 0.7 0.4 1.6 4.1 0.8 3.6 1.8 1.3 1.3 0.3 0.3 1.5 0.0 0.5 0.5 1.1 1.4 0.9 0.3 1.3 3.2 0.5 0.7 0.5 0.9 0.0 2.4 0.0 0.6 2.4 0.1 0.0 0.9 5.7 1.7 2.9 1.5 0.0 0.9 0.5 1.1 1.3 1.8 0.8 0.0 6.9 1.2 0.3 1.5 0.6 1.8 1.8 0.1 1.5 0.3 0.0 1.2 3.5 0.3 5.9 0.1 0.6 0.0 0.4 4.4 4.4 0.9 3.8 3.4 1.8 7.2 0.3 4.9 1.1 2.2 1.4 0.2 0.0 1.1 1.6 0.2 5.4 1.4 1.8 0.3 2.3 3.1 0.6 0.2 7.0 2.7 1.4 1.5 2.0 1.5 0.0 0.0 2.4 0.3 0.0 0.0 0.6 0.6 0.0 0.0 0.9 2.4 0.2 0.0 0.6 0.0 0.0 0.0 0.1 USP53 KIAA1350 ENSG00000145390 "Ubiquitin specific peptidase 53" Q70EK8 4 119212587-119295517 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 82.1;SK-MEL-30: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035844, HPA035845" Uncertain Approved "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA035844: AB_10669532, HPA035845: " "unprognostic (9.33e-2)" "unprognostic (1.49e-2)" "prognostic favourable (3.15e-6)" "unprognostic (4.37e-3)" "unprognostic (4.82e-2)" "unprognostic (5.03e-2)" "unprognostic (1.55e-1)" "unprognostic (9.54e-2)" "unprognostic (1.77e-1)" "unprognostic (9.81e-3)" "unprognostic (1.28e-1)" "prognostic unfavourable (7.54e-6)" "prognostic favourable (3.58e-8)" "unprognostic (9.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" "unprognostic (3.70e-2)" 26.7 11.9 4.6 11.2 7.9 0.7 20.7 10.9 6.2 16.5 15.0 2.9 27.4 4.5 11.6 16.1 17.9 24.7 8.2 18.6 6.4 5.3 20.2 6.6 26.1 8.7 8.8 4.0 11.4 19.3 6.2 33.9 10.4 13.4 10.7 13.1 17.2 17.7 25.8 33.7 11.3 11.2 9.0 15.5 14.1 13.6 10.2 4.9 4.8 10.7 15.6 8.0 20.5 27.0 1.9 0.8 3.1 0.0 2.2 5.1 0.9 2.7 1.6 0.6 0.0 15.7 15.8 3.4 17.6 82.1 1.6 2.1 1.8 2.6 11.3 0.6 5.2 1.3 1.3 1.3 4.1 1.4 1.1 0.7 1.2 0.6 12.3 0.9 0.1 5.2 3.8 5.5 8.0 7.4 1.7 0.4 2.1 0.6 0.6 1.2 1.7 0.9 0.2 2.9 2.2 4.1 1.7 0.9 0.7 0.9 6.9 25.4 1.7 0.6 8.0 0.5 1.8 6.6 1.5 0.8 1.2 1.9 8.0 0.4 2.0 3.1 0.0 0.2 1.3 0.0 1.4 1.7 2.6 2.0 0.4 1.9 5.1 2.7 0.6 2.2 0.0 0.8 2.2 0.9 4.6 7.9 10.9 6.2 6.4 5.3 8.8 4.0 13.4 4.9 USP54 "bA137L10.3, bA137L10.4, C10orf29, FLJ37318" ENSG00000166348 "Ubiquitin specific peptidase 54" Q70EL1 10 73497538-73625953 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.5" "Cell line enhanced" "Detected in many" "PC-3: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047663 Approved Approved Mitochondria Mitochondria "HPA047663: " "unprognostic (2.46e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-2)" "unprognostic (1.89e-2)" "unprognostic (2.48e-2)" "unprognostic (4.89e-3)" "unprognostic (6.63e-4)" "prognostic favourable (7.00e-4)" "unprognostic (6.24e-2)" "unprognostic (4.35e-2)" "unprognostic (8.91e-3)" "unprognostic (3.49e-1)" "unprognostic (1.95e-3)" "unprognostic (8.18e-2)" "unprognostic (6.88e-2)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" 2.9 1.7 12.3 2.5 33.8 0.5 7.7 7.9 21.3 7.9 7.8 43.8 1.8 2.5 4.2 4.5 10.2 7.7 3.1 4.0 14.1 6.8 2.7 1.6 9.0 0.6 49.5 14.2 4.0 6.3 7.1 3.4 1.2 28.6 5.8 11.1 3.4 8.8 3.6 12.0 6.1 2.9 4.0 25.4 1.5 11.3 4.7 42.8 0.4 24.3 1.2 3.6 5.6 4.0 2.4 2.2 1.3 2.4 1.5 3.2 2.3 6.6 6.8 10.6 10.0 2.9 3.4 3.3 3.5 7.0 5.9 6.9 5.7 10.9 5.0 4.2 3.7 9.2 6.8 2.5 7.9 2.4 6.3 3.1 5.0 3.8 2.3 3.4 1.2 2.6 2.4 6.8 6.9 2.7 4.9 0.7 4.1 3.3 3.3 2.2 4.9 24.9 5.0 9.4 1.9 4.2 6.5 3.5 3.3 6.8 8.3 8.0 10.8 3.2 3.7 2.3 6.9 4.5 4.4 1.8 3.3 3.5 5.6 3.2 2.1 0.8 2.3 1.3 1.6 1.9 3.1 2.4 2.7 2.5 1.9 1.0 3.2 1.9 0.1 1.5 2.4 2.2 3.0 2.3 12.3 33.8 7.9 21.3 14.1 6.8 49.5 14.2 28.6 42.8 USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116438-5175034 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "skeletal muscle: 18.2;testis: 29.0" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046969 Uncertain Vesicles Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" 0.3 0.3 0.3 0.3 0.6 0.2 0.4 0.5 0.5 0.3 0.5 0.3 1.2 0.0 0.6 0.6 0.3 0.5 0.4 0.3 0.3 0.1 0.3 0.3 0.3 0.3 0.3 0.3 2.6 0.3 0.0 0.4 0.4 0.3 0.4 0.1 0.3 0.3 0.3 18.2 0.6 0.7 0.9 0.3 0.3 0.0 29.0 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.9 1.2 1.9 1.0 0.2 0.4 0.1 2.2 1.0 2.2 1.7 0.4 0.2 2.3 1.9 0.1 0.6 0.4 0.8 1.1 2.2 1.7 1.3 1.0 0.7 0.8 0.5 1.6 1.3 1.7 1.3 0.9 1.2 0.5 2.9 1.1 0.5 0.1 0.2 0.3 0.5 0.3 0.5 2.5 1.9 0.7 1.6 0.1 1.4 2.0 0.2 0.5 0.7 0.9 2.2 1.0 0.1 3.3 2.2 2.2 1.2 1.0 3.3 2.1 1.4 2.0 1.7 1.5 0.0 0.1 2.7 0.1 0.4 0.9 0.4 0.3 0.2 0.6 0.3 0.3 0.3 0.9 0.3 0.4 1.9 0.2 1.0 1.2 0.1 0.1 0.3 0.6 0.5 0.3 0.3 0.1 0.3 0.3 0.3 0.3 USP7 HAUSP ENSG00000187555 "Ubiquitin specific peptidase 7" Q93009 16 8892094-8964514 "Enzymes, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" "Developmental protein, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008108, HPA015641" Approved "CAB008108: AB_2233500, HPA015641: AB_1858700" "unprognostic (6.73e-2)" "unprognostic (1.59e-1)" "unprognostic (3.36e-3)" "unprognostic (1.94e-2)" "unprognostic (9.64e-2)" "unprognostic (8.09e-2)" "unprognostic (4.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.81e-1)" "unprognostic (2.49e-1)" "unprognostic (2.35e-1)" "unprognostic (9.93e-2)" "prognostic favourable (8.56e-5)" "unprognostic (1.35e-1)" "unprognostic (1.07e-1)" "unprognostic (7.31e-2)" "unprognostic (2.69e-1)" 17.8 16.8 23.9 25.8 22.9 37.6 21.3 28.7 24.5 21.2 26.3 16.2 18.4 17.7 23.5 16.4 24.4 20.3 18.7 23.7 22.8 20.8 16.5 21.3 21.0 30.5 19.6 22.6 22.5 24.0 44.4 19.7 19.3 16.2 18.5 27.4 16.0 18.4 20.3 42.2 25.2 21.5 22.7 15.3 22.9 22.6 43.3 16.5 68.8 19.5 22.3 35.1 23.9 31.7 7.5 9.8 5.5 7.8 3.9 8.7 1.8 12.7 23.7 21.0 15.7 11.9 15.3 14.5 17.6 15.1 16.5 14.0 21.2 15.6 30.7 11.2 20.3 15.9 32.1 21.0 27.6 20.1 12.8 25.5 16.0 43.8 17.3 28.0 16.5 13.2 13.3 17.9 21.2 23.3 24.6 34.1 16.7 24.3 41.1 5.4 14.7 13.8 36.6 23.6 28.0 11.5 25.0 19.8 12.2 19.7 18.5 9.7 18.5 12.6 19.9 17.8 18.2 27.3 13.1 16.5 40.4 47.0 16.6 16.4 14.3 5.5 3.3 3.8 7.1 3.2 8.7 5.9 6.6 8.2 3.3 7.5 8.0 6.8 5.2 3.9 7.8 9.8 7.0 1.8 23.9 22.9 28.7 24.5 22.8 20.8 19.6 22.6 16.2 16.5 USP8 "HumORF8, KIAA0055, SPG59, UBPY" ENSG00000138592 "Ubiquitin specific peptidase 8" P40818 15 50424380-50514419 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050215 Approved Supported "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA050215: " "unprognostic (5.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "unprognostic (9.58e-2)" "unprognostic (2.35e-2)" "unprognostic (2.91e-1)" "unprognostic (1.42e-1)" "unprognostic (3.96e-1)" "unprognostic (1.68e-2)" "unprognostic (5.08e-2)" "unprognostic (2.94e-1)" "unprognostic (3.99e-2)" "prognostic favourable (1.29e-5)" "unprognostic (4.89e-2)" "unprognostic (1.13e-1)" "unprognostic (3.79e-1)" "unprognostic (1.58e-1)" 19.4 21.9 21.0 20.6 20.6 21.6 18.1 27.3 21.6 21.4 23.9 13.8 19.5 20.2 22.1 17.4 22.3 17.4 15.5 17.4 19.7 18.2 28.2 26.4 17.0 25.4 21.8 15.2 21.9 16.7 42.6 43.2 29.1 29.7 16.7 18.9 10.7 19.9 17.9 24.3 17.8 32.1 19.2 29.3 30.3 17.7 27.5 26.1 28.9 24.1 12.7 20.9 22.3 18.4 16.7 10.6 38.1 15.1 9.5 11.9 6.9 11.0 15.9 8.9 15.7 16.3 18.3 12.4 15.9 18.9 15.5 18.4 10.6 7.3 11.7 12.3 18.2 21.5 12.2 11.9 18.4 10.2 8.1 21.6 14.8 10.9 16.8 14.4 14.6 14.2 14.3 13.7 23.3 15.0 12.3 14.2 14.5 22.7 9.2 5.7 10.2 7.3 8.4 16.6 17.5 14.7 26.1 11.4 10.4 16.8 25.1 20.8 13.7 17.7 17.0 16.1 9.1 49.6 21.0 11.1 23.1 12.9 12.9 29.2 15.5 38.1 13.3 22.4 11.1 12.4 10.7 16.5 11.4 11.1 10.6 16.7 11.9 10.7 22.7 9.5 15.1 9.9 8.5 6.9 21.0 20.6 27.3 21.6 19.7 18.2 21.8 15.2 29.7 26.1 USP9X "DFFRX, FAF, MRX99" ENSG00000124486 "Ubiquitin specific peptidase 9, X-linked" Q93008 X 41085635-41236579 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Chromosome partition, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011618, HPA047417, CAB070164" Approved Uncertain Vesicles Vesicles "CAB011618: AB_470860, CAB070164: AB_10011071, HPA047417: " "unprognostic (5.42e-3)" "unprognostic (6.42e-2)" "unprognostic (3.19e-3)" "unprognostic (2.94e-2)" "unprognostic (5.99e-2)" "unprognostic (4.76e-1)" "unprognostic (1.82e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.07e-2)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" 18.0 21.8 17.7 14.0 15.9 15.5 16.8 16.6 16.7 18.4 20.6 11.4 25.4 13.2 19.6 19.0 17.3 17.0 17.1 20.9 14.2 14.2 18.5 34.2 16.7 23.1 15.2 15.4 15.7 16.5 45.8 17.0 41.1 12.9 13.4 14.4 13.9 14.2 25.2 42.8 14.8 22.0 17.3 14.0 16.7 16.9 16.9 14.0 21.1 20.3 17.6 16.5 20.3 19.9 6.4 5.5 13.0 5.0 4.9 7.8 3.1 19.0 22.6 20.1 20.5 16.9 17.7 4.6 11.0 14.8 12.5 14.6 10.4 8.9 12.8 6.2 25.0 12.9 34.5 20.0 21.1 16.1 24.8 14.9 21.9 9.3 14.3 12.9 10.9 15.3 9.0 30.0 28.5 19.3 18.0 10.5 19.3 14.0 9.2 5.1 21.2 12.5 10.1 27.5 8.3 11.9 15.8 11.4 10.7 46.2 12.8 12.6 12.4 7.2 20.6 19.2 14.8 18.1 11.8 9.6 11.2 16.4 13.7 5.8 9.5 3.3 4.7 6.0 5.6 4.2 7.8 6.4 6.6 6.2 5.5 4.7 6.7 6.0 13.0 4.9 5.0 4.2 5.6 3.1 17.7 15.9 16.6 16.7 14.2 14.2 15.2 15.4 12.9 14.0 USP9Y DFFRY ENSG00000114374 "Ubiquitin specific peptidase 9, Y-linked" O00507 Y 12701231-12860839 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 16.0;RT4: 8.6" "Cancer enhanced" "Detected in many" "prostate cancer: 5.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.4;dendritic cells: 2.0;T-cells: 2.7" "Not detected" "Not detected" HPA057687 Uncertain Vesicles Vesicles "HPA057687: " "unprognostic (2.63e-1)" "unprognostic (8.97e-2)" "unprognostic (1.10e-5)" "unprognostic (8.46e-3)" "unprognostic (4.93e-2)" "unprognostic (2.53e-2)" "unprognostic (2.77e-1)" "unprognostic (3.17e-2)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-4)" "unprognostic (2.28e-1)" "unprognostic (1.19e-2)" "unprognostic (1.42e-1)" 1.2 2.2 1.4 0.9 3.1 1.7 1.1 9.6 4.0 0.0 1.6 1.4 0.0 8.6 4.4 0.0 3.8 2.4 1.8 3.4 2.9 2.2 2.2 1.4 2.1 0.0 2.7 0.0 4.8 1.7 9.3 4.8 2.3 7.6 2.8 2.0 1.8 0.0 1.5 2.2 1.5 2.9 2.8 4.5 3.2 0.0 2.4 2.0 0.1 0.2 0.5 2.7 0.2 0.0 2.2 0.0 0.0 0.0 0.0 2.4 7.1 7.1 3.6 3.9 0.0 0.0 4.0 0.0 5.9 0.0 0.0 0.0 3.2 2.2 0.0 2.5 0.0 7.0 4.0 0.0 0.0 5.9 5.2 0.0 0.0 0.0 0.0 0.0 6.4 0.0 4.0 0.0 1.5 0.0 0.0 2.0 0.8 16.0 8.6 2.8 0.0 0.0 0.0 2.1 0.0 0.0 5.5 4.4 0.0 0.0 3.2 0.0 3.7 7.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.2 2.7 1.2 2.2 1.5 0.3 2.4 2.2 1.3 0.1 0.5 0.0 2.0 1.6 0.2 USPL1 "bA121O19.1, C13orf22, D13S106E" ENSG00000132952 "Ubiquitin specific peptidase like 1" Q5W0Q7 13 30617693-30660770 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039342, HPA040172" Uncertain "HPA039342: AB_10795105, HPA040172: AB_10796447" "unprognostic (5.74e-2)" "unprognostic (6.26e-2)" "unprognostic (8.16e-2)" "unprognostic (4.29e-2)" "unprognostic (4.96e-2)" "unprognostic (3.65e-1)" "unprognostic (1.00e-2)" "unprognostic (1.65e-1)" "unprognostic (1.20e-1)" "unprognostic (6.79e-2)" "unprognostic (2.21e-2)" "unprognostic (1.27e-2)" "unprognostic (3.18e-1)" "unprognostic (2.68e-1)" "unprognostic (1.49e-1)" "unprognostic (3.78e-1)" "unprognostic (5.32e-3)" 12.6 10.0 13.0 16.2 14.9 29.7 13.2 22.1 14.6 11.5 10.3 9.6 8.7 8.8 14.2 10.5 10.1 11.4 9.0 7.5 12.9 7.8 9.4 15.3 12.2 16.7 20.8 10.4 16.2 13.1 6.6 15.2 11.7 13.7 13.4 9.9 7.4 9.8 10.1 10.0 13.6 14.3 9.9 18.0 19.7 10.4 23.1 18.9 12.5 12.3 5.8 16.1 14.1 42.6 11.3 6.9 7.5 7.7 8.4 10.6 5.9 4.2 6.3 14.8 8.8 7.5 9.4 6.2 9.9 7.9 9.8 7.8 8.6 11.4 9.5 5.0 8.4 8.8 15.5 5.8 14.5 8.0 6.4 11.8 9.5 7.5 6.8 11.3 9.6 6.8 10.6 7.1 9.9 14.2 11.9 6.3 10.7 3.6 15.6 22.9 12.5 4.2 14.9 11.0 8.7 7.9 2.8 12.7 11.8 5.4 6.2 8.7 7.0 14.2 8.9 6.8 6.7 8.9 7.3 6.6 5.6 13.9 3.9 7.9 13.2 6.1 7.7 7.5 7.7 5.8 10.6 11.0 7.5 7.8 6.9 11.3 10.2 9.2 3.8 8.4 4.6 5.2 7.8 5.9 13.0 14.9 22.1 14.6 12.9 7.8 20.8 10.4 13.7 18.9 UXS1 "FLJ23591, SDR6E1, UGD" ENSG00000115652 "UDP-glucuronate decarboxylase 1" Q8NBZ7 2 106093303-106194339 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 82.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008825 Uncertain "Intracellular and membrane" 10000 "HPA008825: AB_1858708" "unprognostic (4.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.63e-2)" "unprognostic (3.92e-2)" "prognostic unfavourable (5.45e-4)" "prognostic unfavourable (1.38e-4)" "unprognostic (3.20e-3)" "unprognostic (2.07e-1)" "prognostic favourable (7.94e-4)" "unprognostic (3.95e-2)" "unprognostic (1.40e-2)" "unprognostic (8.46e-2)" "unprognostic (3.96e-2)" "unprognostic (6.18e-2)" "unprognostic (1.86e-2)" "unprognostic (5.32e-2)" 12.3 11.7 15.2 17.3 19.9 20.7 20.1 23.0 20.5 14.1 13.3 11.9 27.6 9.5 16.1 22.3 15.6 19.2 16.2 20.0 17.0 18.2 40.2 16.1 28.8 20.7 15.1 11.6 16.3 17.0 18.6 13.4 37.9 19.6 16.2 15.6 14.7 11.6 17.6 18.0 11.5 9.9 13.8 22.9 19.7 17.9 19.4 10.6 15.0 26.2 14.1 19.1 21.6 15.3 11.6 7.5 11.2 9.8 11.9 34.1 15.1 16.2 12.4 13.0 9.8 23.3 17.4 28.2 18.0 17.0 12.8 16.0 24.2 27.9 3.0 22.5 18.7 8.2 5.7 14.8 14.0 15.7 9.9 9.0 5.5 27.1 9.2 7.3 10.0 11.2 16.3 13.0 8.8 13.4 5.2 7.2 26.4 11.6 8.1 15.6 15.3 16.6 15.1 9.8 8.4 82.7 15.4 4.3 4.8 12.9 11.7 10.7 4.4 23.3 12.0 14.4 15.1 11.6 11.1 8.9 12.2 4.1 14.3 16.4 26.4 3.9 9.8 11.2 8.8 8.0 9.5 4.9 19.6 14.3 7.5 11.6 25.4 17.6 2.0 11.9 5.3 5.4 34.1 15.1 15.2 19.9 23.0 20.5 17.0 18.2 15.1 11.6 19.6 10.6 VARS VARS2 ENSG00000204394 "Valyl-tRNA synthetase" P26640 6 31777518-31795953 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 24.8;U-266/84: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046710 Approved Enhanced Cytosol 23000 Cytosol "HPA046710: " "unprognostic (1.86e-2)" "prognostic unfavourable (7.25e-4)" "unprognostic (2.19e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-2)" "unprognostic (3.43e-2)" "prognostic unfavourable (1.86e-4)" "prognostic unfavourable (6.90e-4)" "unprognostic (3.20e-1)" "unprognostic (2.76e-1)" "unprognostic (4.72e-1)" "unprognostic (1.28e-1)" "unprognostic (1.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.69e-1)" "unprognostic (3.85e-2)" "unprognostic (2.59e-1)" 11.7 11.4 8.9 12.0 9.5 9.1 18.3 7.6 14.0 8.1 11.3 7.3 5.0 12.8 13.5 6.7 14.2 10.2 8.1 9.5 6.4 6.8 9.5 22.7 11.5 24.2 8.3 9.7 9.6 19.2 15.6 15.0 8.5 8.6 7.7 9.4 6.1 9.1 5.9 30.6 14.3 10.3 13.2 8.7 14.4 15.2 40.6 7.5 10.9 8.2 13.2 11.8 9.7 8.5 1.6 1.5 0.6 1.2 2.4 1.0 0.9 2.2 2.0 3.1 6.3 3.5 2.8 8.5 8.6 2.6 6.5 3.9 2.6 1.4 7.6 10.7 5.4 2.4 10.0 6.6 3.9 5.5 14.2 3.7 5.1 6.0 4.6 15.0 12.4 4.2 2.4 2.6 6.0 3.2 10.4 10.3 4.2 3.4 6.8 0.7 6.0 4.2 8.8 1.6 24.8 5.0 2.8 3.9 1.4 0.7 8.5 3.7 5.2 6.0 1.1 4.5 4.2 6.0 14.2 14.8 25.4 6.2 3.3 3.0 5.0 0.0 0.6 0.6 1.0 1.2 1.0 1.6 0.6 0.4 1.1 1.1 0.8 0.8 0.0 2.4 1.0 1.5 0.6 0.9 8.9 9.5 7.6 14.0 6.4 6.8 8.3 9.7 8.6 7.5 VARS2 "DKFZP434L1435, G7a, KIAA1885, VARS2L, VARSL" ENSG00000137411 "Valyl-tRNA synthetase 2, mitochondrial" Q5ST30 6 30908242-30926459 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 14.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062449, HPA070267" Approved Approved Mitochondria Mitochondria "HPA062449: , HPA070267: " "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "unprognostic (1.96e-3)" "unprognostic (2.50e-1)" "unprognostic (5.80e-2)" "unprognostic (3.05e-2)" "unprognostic (2.43e-2)" "unprognostic (1.66e-2)" "unprognostic (3.14e-1)" "unprognostic (8.98e-2)" "unprognostic (4.23e-2)" "unprognostic (2.60e-2)" "unprognostic (2.15e-3)" "unprognostic (1.04e-2)" "unprognostic (7.23e-2)" "unprognostic (1.19e-2)" "unprognostic (2.43e-2)" 7.2 7.8 6.3 12.5 8.6 6.9 6.8 21.4 11.4 4.2 6.5 8.9 6.2 6.2 8.8 6.2 20.6 6.3 7.4 4.9 7.4 6.4 12.0 13.5 7.3 12.9 5.6 9.3 8.8 12.5 8.5 9.7 5.1 7.9 6.0 8.1 4.6 8.2 10.5 9.4 11.0 7.4 4.4 6.3 7.8 8.6 8.3 3.4 13.4 8.2 4.6 10.0 4.8 6.1 1.8 1.3 0.1 0.9 0.2 1.8 0.5 8.5 6.9 3.7 14.8 3.1 2.3 0.1 1.2 0.8 1.2 1.1 6.0 4.9 6.5 5.1 0.9 0.0 10.3 0.0 1.9 3.3 8.9 7.8 5.8 0.6 2.7 1.6 0.0 1.8 2.6 3.7 0.8 0.9 0.0 7.4 3.0 0.0 2.5 0.0 0.9 0.9 6.1 0.0 6.3 4.9 0.0 4.5 0.1 0.0 3.3 3.7 10.1 4.1 1.6 9.2 0.6 0.5 0.1 6.8 10.5 13.4 0.0 0.3 6.1 0.0 0.2 0.0 1.1 0.9 1.8 1.8 1.0 1.6 1.0 0.7 0.6 0.3 0.1 0.2 0.6 1.3 1.2 0.5 6.3 8.6 21.4 11.4 7.4 6.4 5.6 9.3 7.9 3.4 VCP "CDC48, IBMPFD, p97, TERA" ENSG00000165280 "Valosin containing protein" P55072 9 35056064-35073249 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, DNA damage, DNA repair, Transport, Ubl conjugation pathway" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005593, HPA012728, HPA012814" Supported Enhanced Nucleoplasm,Cytosol 110000000 "Nucleoplasm, Cytosol" "CAB005593: AB_2214638, HPA012728: AB_1858730, HPA012814: AB_1858729" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.15e-2)" "prognostic favourable (7.30e-4)" "unprognostic (5.78e-2)" "unprognostic (1.87e-1)" "unprognostic (2.52e-3)" "unprognostic (1.13e-2)" "unprognostic (3.82e-2)" "unprognostic (1.81e-2)" "unprognostic (2.19e-2)" "unprognostic (3.24e-1)" "prognostic favourable (9.63e-7)" "unprognostic (1.83e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-1)" "unprognostic (9.11e-2)" 33.7 43.6 19.6 30.3 21.8 30.8 31.4 19.4 31.0 32.2 25.7 22.7 32.9 22.2 30.5 34.0 40.0 24.7 33.8 69.6 20.0 23.4 30.1 63.4 27.6 42.7 23.1 21.1 25.0 34.9 44.5 29.0 46.3 26.3 33.4 26.5 21.2 30.7 34.1 80.4 29.2 26.3 29.2 23.0 37.8 28.9 25.6 18.2 43.3 32.1 42.2 35.7 31.5 26.5 25.9 29.4 43.4 30.6 23.0 32.1 34.4 36.0 41.2 28.4 15.3 34.3 24.2 21.7 33.6 38.1 50.3 37.2 27.5 14.9 28.6 29.5 41.7 17.4 42.3 40.1 43.6 30.7 24.5 19.9 38.9 37.6 26.6 22.3 26.6 27.6 27.0 43.5 19.5 54.3 20.6 20.8 40.1 25.4 21.8 53.7 37.0 39.4 19.4 22.1 17.7 39.3 25.8 15.5 19.5 20.3 23.0 10.2 18.5 15.9 44.4 20.2 26.1 17.9 29.4 10.6 22.4 24.5 33.1 16.1 25.8 43.4 24.5 31.9 24.7 27.2 23.8 25.9 23.6 24.8 29.4 21.1 17.7 18.5 28.4 23.0 30.6 18.9 32.1 34.4 19.6 21.8 19.4 31.0 20.0 23.4 23.1 21.1 26.3 18.2 VCPIP1 "DUBA3, FLJ23132, KIAA1850, VCIP135" ENSG00000175073 "Valosin containing protein interacting protein 1" Q96JH7 8 66628487-66667217 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023932 Uncertain Approved "Plasma membrane,Centrosome" "Plasma membrane" Centrosome "HPA023932: " "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (4.01e-2)" "unprognostic (5.56e-2)" "unprognostic (5.23e-2)" "unprognostic (7.21e-2)" "unprognostic (2.80e-1)" "unprognostic (3.96e-1)" "unprognostic (5.23e-3)" "unprognostic (7.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-2)" "unprognostic (8.58e-3)" 9.5 8.7 15.7 12.6 14.5 30.9 8.9 14.4 15.1 7.5 8.4 7.0 3.8 7.0 7.8 8.7 8.1 6.9 7.0 6.7 10.2 9.2 8.3 12.3 10.5 13.6 10.3 13.7 7.8 9.0 14.0 5.9 8.0 12.3 7.0 7.8 6.0 9.0 7.1 14.8 7.3 10.0 6.3 9.6 14.7 8.0 10.8 11.7 11.6 8.0 2.8 13.3 7.9 7.0 2.6 3.4 11.3 8.8 2.8 4.3 1.7 8.8 8.0 4.2 5.5 12.7 9.0 4.0 7.1 7.2 5.5 6.3 4.7 8.4 11.9 2.1 9.5 7.9 6.7 5.9 7.9 8.9 4.8 13.3 7.9 5.9 7.7 4.4 14.3 9.7 8.8 5.9 10.8 5.9 8.9 11.6 8.0 4.3 9.5 7.6 7.9 5.6 6.1 6.5 6.0 7.9 7.0 2.4 4.7 5.5 8.4 6.1 8.6 7.3 11.8 7.2 5.4 6.3 4.7 10.3 5.0 12.8 7.2 6.4 5.4 9.2 3.2 6.7 4.3 5.2 3.6 2.0 2.7 3.1 3.4 2.6 2.2 2.9 11.3 2.8 8.8 1.3 3.3 1.7 15.7 14.5 14.4 15.1 10.2 9.2 10.3 13.7 12.3 11.7 VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 173.3" "Cell line enhanced" "Detected in all" "ASC diff: 98.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" 21.3 23.0 9.3 11.5 11.0 12.9 28.1 9.4 14.5 24.3 19.3 17.1 16.5 12.6 24.0 27.4 18.5 17.8 22.6 20.1 9.8 10.2 29.9 173.3 16.4 17.5 13.7 9.1 25.5 55.5 14.0 25.0 22.5 13.3 22.3 12.6 20.8 34.8 21.4 11.4 15.9 26.8 27.7 12.5 15.4 17.5 18.2 10.6 15.8 25.6 13.8 14.6 28.4 18.7 32.3 49.9 59.6 40.6 24.7 43.7 33.6 10.4 26.9 8.9 25.3 98.2 58.5 9.9 38.9 33.8 19.1 32.6 11.2 12.1 8.2 21.0 48.6 9.7 12.2 15.2 21.8 11.6 29.7 7.5 37.3 53.6 15.5 14.5 11.3 33.8 8.2 26.4 22.7 20.7 9.8 19.6 37.4 37.9 10.6 29.8 16.0 25.9 19.3 23.5 40.9 18.9 9.2 18.1 21.9 17.0 12.4 18.8 20.4 17.7 18.0 25.7 9.2 23.6 14.6 11.9 11.0 7.2 66.9 25.1 13.2 21.5 40.6 59.6 40.3 28.1 39.7 29.9 40.5 40.7 39.6 32.3 36.4 35.4 34.2 24.7 28.3 49.9 43.7 33.6 9.3 11.0 9.4 14.5 9.8 10.2 13.7 9.1 13.3 10.6 VKORC1L1 ENSG00000196715 "Vitamin K epoxide reductase complex subunit 1 like 1" Q8N0U8 7 65873267-65959563 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA053954 Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA053954: " "unprognostic (3.01e-1)" "unprognostic (1.76e-3)" "unprognostic (4.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-3)" "unprognostic (7.15e-3)" "unprognostic (1.30e-3)" "unprognostic (8.84e-3)" "unprognostic (5.12e-2)" "unprognostic (5.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.07e-1)" "unprognostic (1.59e-2)" "unprognostic (1.17e-1)" "unprognostic (7.03e-3)" "unprognostic (4.30e-1)" "unprognostic (5.06e-2)" 38.2 9.2 10.5 8.3 16.7 3.0 23.7 9.0 19.7 10.4 11.1 14.2 9.2 8.6 10.1 8.8 10.0 8.8 8.0 9.3 10.3 11.4 8.2 17.8 14.3 6.2 12.0 12.1 14.4 11.7 28.5 8.0 9.7 14.1 9.9 10.0 8.0 9.0 10.5 14.9 11.4 9.7 9.3 13.2 5.7 9.9 9.4 7.6 9.1 11.1 4.5 6.6 9.7 9.3 2.8 7.5 5.6 4.2 6.5 3.4 1.8 22.1 14.4 11.6 14.5 37.0 14.7 21.1 24.2 15.7 14.5 14.7 13.8 22.0 19.4 19.6 17.3 15.3 16.5 9.8 24.2 12.1 16.3 13.2 13.1 11.8 18.1 18.3 10.2 11.8 12.6 14.7 20.5 14.3 27.7 14.9 17.2 8.7 14.9 21.3 27.8 10.8 16.5 16.9 24.1 13.9 9.0 14.0 19.9 18.7 33.9 10.6 17.1 14.2 16.2 23.5 16.1 14.7 24.5 13.4 21.9 22.3 14.4 20.8 20.4 3.8 2.7 5.6 2.9 2.5 2.4 2.8 3.4 3.2 2.8 2.5 2.3 2.3 3.1 6.5 4.2 7.5 3.1 1.8 10.5 16.7 9.0 19.7 10.3 11.4 12.0 12.1 14.1 7.6 VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132681590-132714049 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 131.9;liver: 112.2" "Cell line enhanced" "Detected in some" "A-431: 4.0;CAPAN-2: 4.2;EFO-21: 14.8;HBEC3-KT: 3.9;LHCN-M2: 4.2" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "classical monocyte: 13.4" "Group enriched" "Detected in many" 71 "dendritic cells: 4.9;granulocytes: 8.0;monocytes: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA064145 Uncertain "Intracellular and membrane" 1100000000 "HPA064145: " "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavourable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" 1.8 0.4 0.3 0.6 0.3 2.4 0.7 0.2 0.3 0.4 128.6 0.1 0.0 40.6 2.5 0.2 0.6 1.7 27.0 1.1 0.3 0.3 6.5 112.2 7.9 2.4 0.4 0.1 0.4 0.9 0.0 0.3 1.0 0.5 0.4 0.3 0.2 1.5 0.1 0.4 0.5 131.9 0.0 0.5 5.6 0.8 0.5 0.1 0.2 0.4 0.0 0.4 0.4 0.9 0.1 4.9 8.0 13.4 0.0 0.0 3.6 4.0 0.0 0.5 0.1 0.1 1.3 0.9 0.3 0.3 0.0 0.0 0.1 4.2 0.2 14.8 0.0 0.1 0.0 3.9 1.0 0.1 0.0 0.2 0.2 2.3 2.3 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 4.2 0.2 0.0 0.6 0.1 0.2 0.1 0.2 1.7 0.9 0.3 0.2 0.6 0.1 0.0 0.0 0.0 0.0 2.6 1.0 0.1 0.4 0.2 0.4 0.0 0.1 0.4 0.1 0.6 2.3 13.4 0.0 0.0 7.4 0.0 0.0 0.0 0.0 4.9 0.1 0.0 0.0 8.0 0.0 10.2 0.2 0.0 3.6 0.3 0.3 0.2 0.3 0.3 0.3 0.4 0.1 0.5 0.1 VPS4A "FLJ22197, SKD1, SKD1A, SKD2, VPS4, VPS4-1" ENSG00000132612 "Vacuolar protein sorting 4 homolog A" Q9UN37 16 69311356-69326939 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB018751, CAB034411, HPA060092" Approved Supported Midbody Midbody "CAB018751: AB_2215497, CAB034411: AB_2304400, HPA060092: " "unprognostic (2.60e-2)" "unprognostic (2.32e-2)" "unprognostic (1.26e-1)" "unprognostic (9.26e-2)" "unprognostic (4.03e-1)" "unprognostic (1.20e-1)" "unprognostic (2.55e-2)" "unprognostic (2.70e-2)" "unprognostic (4.63e-2)" "unprognostic (8.61e-2)" "unprognostic (3.91e-3)" "unprognostic (2.19e-1)" "prognostic favourable (1.76e-4)" "unprognostic (5.44e-2)" "unprognostic (1.46e-1)" "unprognostic (2.61e-1)" "unprognostic (6.79e-2)" 20.2 19.6 24.8 14.4 26.5 13.0 24.2 28.7 35.6 12.9 17.8 19.3 14.5 22.0 16.6 14.5 26.3 16.0 16.1 34.3 24.4 22.8 23.2 13.7 15.8 17.5 25.4 29.3 21.0 31.4 29.7 9.6 16.6 33.6 17.5 13.2 15.6 30.4 15.5 81.6 24.3 20.5 18.4 34.3 15.0 18.9 15.5 17.4 8.9 27.5 21.1 13.0 15.6 21.2 11.1 11.6 15.7 13.1 9.3 18.1 14.4 10.9 18.8 13.1 17.1 11.8 10.5 11.4 15.0 13.6 19.9 13.4 17.7 10.3 18.6 14.9 14.8 16.5 12.9 15.1 12.0 7.8 16.7 11.7 11.3 14.3 18.3 14.5 10.9 12.1 19.8 17.2 15.8 14.7 19.3 5.6 14.6 24.5 18.8 11.0 14.7 13.3 25.5 10.5 21.8 10.0 9.0 21.7 13.9 31.9 10.0 11.4 17.4 11.0 17.5 18.4 11.6 16.7 11.6 20.3 16.0 33.8 16.9 9.9 20.2 10.0 11.6 15.7 14.6 10.2 13.3 11.1 12.3 18.1 11.6 10.1 14.3 13.0 9.5 9.3 13.1 6.8 13.8 14.4 24.8 26.5 28.7 35.6 24.4 22.8 25.4 29.3 33.6 17.4 VPS4B "SKD1, SKD1B, VPS4-2" ENSG00000119541 "Vacuolar protein sorting 4 homolog B" O75351 18 63389190-63422483 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040393, CAB046445, HPA057649" Approved Approved "Vesicles,Intermediate filaments" 34000 Vesicles "Intermediate filaments" "CAB046445: AB_10603252, HPA040393: , HPA057649: " "unprognostic (8.54e-2)" "unprognostic (1.06e-1)" "unprognostic (1.85e-3)" "unprognostic (5.59e-2)" "unprognostic (1.71e-1)" "unprognostic (9.47e-2)" "unprognostic (1.75e-1)" "unprognostic (1.79e-1)" "unprognostic (4.54e-2)" "unprognostic (9.10e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "prognostic favourable (1.23e-4)" "unprognostic (4.59e-1)" "unprognostic (1.40e-1)" "unprognostic (4.08e-1)" "unprognostic (1.21e-1)" 16.8 13.0 14.3 14.3 17.2 28.0 17.2 15.4 19.1 19.8 24.0 21.8 15.5 20.0 16.7 12.1 55.0 13.1 15.1 9.9 13.7 16.0 15.6 20.5 14.3 21.6 17.0 14.7 11.9 14.0 17.5 17.4 27.4 23.4 14.3 22.2 9.3 21.8 15.0 9.9 22.1 28.7 15.2 20.2 17.3 18.7 9.0 14.6 27.8 17.0 17.6 31.8 18.6 24.7 20.7 13.6 56.4 20.6 19.1 18.9 15.4 18.4 6.8 7.6 8.3 11.8 16.7 13.2 16.2 15.3 12.4 13.6 5.0 13.2 17.8 10.6 11.8 40.1 9.1 17.7 16.5 12.9 7.3 8.9 9.6 7.7 16.9 30.6 19.5 15.1 27.6 10.9 19.5 11.5 4.4 16.7 17.6 6.4 19.1 9.6 7.9 10.7 16.0 16.2 17.1 15.6 21.7 13.0 11.5 12.2 12.0 18.1 11.5 16.7 17.6 19.2 9.4 7.2 10.6 56.1 26.9 22.9 11.0 14.5 14.2 39.4 16.8 36.0 16.5 16.6 15.4 18.9 17.4 17.0 13.6 20.7 15.8 16.6 56.4 19.1 20.6 13.6 18.9 15.4 14.3 17.2 15.4 19.1 13.7 16.0 17.0 14.7 23.4 14.6 VRK1 ENSG00000100749 "Vaccinia related kinase 1" Q99986 14 96797304-96931722 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavourable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" 6.0 4.4 7.1 9.8 17.1 39.0 8.7 8.6 10.2 6.1 7.8 4.4 4.1 5.2 5.9 5.7 9.4 6.9 3.3 6.0 7.4 6.5 6.2 4.3 4.5 18.3 6.9 6.1 5.9 3.7 3.8 5.1 7.1 6.7 5.3 9.1 4.1 4.8 4.1 4.3 6.4 6.9 5.4 6.1 15.7 6.7 33.3 6.9 33.0 4.9 6.1 18.4 5.9 5.7 20.8 13.5 20.1 9.5 28.5 22.3 12.5 15.7 9.1 22.5 10.0 2.7 5.0 14.0 11.9 9.3 19.1 19.0 10.8 15.6 40.1 8.1 7.0 17.5 21.0 15.5 26.3 22.8 11.3 25.0 6.0 11.1 2.9 48.0 15.7 2.7 2.8 14.4 10.6 13.2 21.2 25.4 16.4 18.0 38.1 20.7 14.4 17.3 35.7 39.4 13.6 8.7 16.2 15.9 9.0 10.5 10.8 8.0 12.3 19.0 7.1 8.7 7.8 15.0 11.9 13.3 15.7 38.8 13.6 21.0 10.3 20.1 7.6 14.5 15.1 9.3 18.4 20.3 17.6 18.5 9.9 20.8 19.1 19.3 4.5 28.5 9.5 13.5 22.3 12.5 7.1 17.1 8.6 10.2 7.4 6.5 6.9 6.1 6.7 6.9 VRK2 ENSG00000028116 "Vaccinia related kinase 2" Q86Y07 2 57907651-58159920 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046459, HPA047503" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB046459: AB_1858773, HPA047503: " "unprognostic (1.87e-1)" "unprognostic (5.84e-2)" "unprognostic (4.65e-2)" "unprognostic (1.33e-3)" "unprognostic (1.27e-1)" "unprognostic (1.60e-2)" "prognostic unfavourable (6.32e-6)" "unprognostic (3.90e-2)" "unprognostic (4.76e-2)" "unprognostic (2.96e-2)" "prognostic unfavourable (4.65e-4)" "unprognostic (1.36e-1)" "prognostic unfavourable (4.66e-5)" "unprognostic (3.48e-1)" "unprognostic (1.62e-1)" "unprognostic (2.99e-1)" "unprognostic (3.56e-1)" 18.7 17.7 10.9 21.9 28.3 14.9 16.1 2.4 15.1 15.6 13.5 27.3 16.3 9.9 18.4 16.7 26.8 13.2 10.9 21.6 14.4 8.9 12.4 15.2 15.6 19.5 29.2 13.5 14.2 20.0 16.1 18.7 16.1 18.7 15.7 15.6 9.3 20.5 17.6 21.5 12.8 12.9 20.1 19.0 20.1 13.5 12.5 31.2 13.6 17.4 16.7 23.0 18.1 19.4 19.7 17.0 21.6 21.3 11.3 12.2 9.2 14.1 9.5 1.1 6.3 7.1 13.1 19.6 13.1 13.2 9.1 9.3 19.3 15.1 17.3 17.3 11.5 10.8 13.7 14.3 13.7 31.1 9.2 19.5 7.6 13.8 11.3 16.5 11.6 7.2 17.1 14.6 21.0 26.1 19.1 11.1 15.1 8.1 0.1 12.7 12.0 4.8 18.9 4.8 11.8 15.1 11.7 3.8 0.1 20.8 12.4 10.5 8.7 10.2 14.5 0.2 30.2 8.1 0.2 16.4 12.9 9.3 7.3 20.5 15.0 13.7 16.8 21.6 10.1 21.3 12.2 19.7 9.8 11.8 16.6 19.0 7.4 9.5 6.0 11.3 20.6 17.0 11.5 9.2 10.9 28.3 2.4 15.1 14.4 8.9 29.2 13.5 18.7 31.2 VRK3 ENSG00000105053 "Vaccinia related kinase 3" Q8IV63 19 49976467-50025946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 77.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056489 Approved Supported Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA056489: " "unprognostic (2.09e-1)" "unprognostic (3.14e-2)" "unprognostic (1.26e-1)" "unprognostic (4.94e-3)" "unprognostic (1.23e-1)" "unprognostic (2.22e-3)" "unprognostic (9.78e-2)" "unprognostic (3.47e-1)" "unprognostic (8.79e-2)" "unprognostic (2.48e-1)" "unprognostic (1.31e-2)" "unprognostic (1.43e-1)" "prognostic favourable (1.83e-4)" "unprognostic (9.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.06e-1)" "prognostic favourable (5.66e-4)" 9.7 11.9 9.2 9.4 12.7 10.7 8.3 12.0 14.1 8.9 13.4 11.9 9.3 13.4 15.7 10.8 8.4 18.0 12.2 7.4 9.3 11.1 16.7 16.2 8.5 13.4 10.4 9.9 11.2 11.5 7.1 11.8 10.7 9.8 9.4 11.7 14.2 14.3 8.5 11.8 7.7 17.3 7.5 11.0 12.8 10.9 77.2 9.1 24.7 14.1 6.0 12.9 9.9 8.0 24.5 19.7 47.3 20.9 33.5 30.1 18.1 16.3 16.9 12.4 13.4 16.5 15.3 12.9 11.8 14.1 17.5 19.3 9.0 18.3 19.7 8.4 11.4 12.2 11.5 10.0 14.2 17.2 23.7 15.3 10.2 15.6 12.4 19.1 27.0 13.7 15.1 10.1 10.7 14.4 18.6 29.4 12.6 6.9 25.8 12.9 6.7 14.6 20.8 13.1 25.1 15.0 17.3 14.0 6.8 11.5 14.2 12.8 13.1 20.4 10.9 18.0 10.5 7.2 9.1 19.1 24.3 10.3 14.4 11.8 12.3 37.0 17.8 32.4 23.8 18.8 19.1 24.5 21.7 22.7 19.7 21.9 22.1 20.4 47.3 33.5 20.9 18.8 30.1 18.1 9.2 12.7 12.0 14.1 9.3 11.1 10.4 9.9 9.8 9.1 WARS "IFI53, IFP53" ENSG00000140105 "Tryptophanyl-tRNA synthetase" P23381 14 100333788-100376805 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 142.8;thyroid gland: 157.0" "Cell line enhanced" "Detected in all" "HHSteC: 116.6;SK-MEL-30: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "intermediate monocyte: 131.2;non-classical monocyte: 142.8" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol 53000000 Cytosol "HPA005573: , HPA018944: " "unprognostic (5.36e-2)" "unprognostic (5.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.25e-2)" "prognostic unfavourable (7.88e-4)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "prognostic favourable (1.94e-4)" "unprognostic (4.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.37e-1)" "unprognostic (9.45e-2)" "unprognostic (1.62e-1)" "unprognostic (5.92e-3)" 42.5 23.3 14.5 53.9 20.1 17.0 20.6 10.7 25.4 11.1 19.1 13.3 7.1 12.7 16.5 20.5 17.8 14.5 13.7 32.0 17.8 18.7 24.6 17.9 68.5 35.3 16.9 14.8 12.1 15.6 9.4 23.5 89.6 28.2 16.4 21.0 23.5 15.7 11.7 22.3 9.3 19.8 21.0 15.7 51.6 19.8 23.7 9.4 20.9 157.0 19.2 22.7 24.0 13.8 5.6 27.7 51.8 142.8 3.3 3.4 46.4 10.9 10.4 6.8 39.9 9.9 14.1 11.0 14.1 27.3 30.5 38.4 6.8 9.8 11.9 13.2 33.7 18.6 19.9 16.1 19.6 18.8 5.7 7.6 7.9 8.3 116.6 21.8 12.6 16.0 23.2 17.7 36.8 27.2 24.0 31.5 13.0 20.9 7.5 10.2 6.9 18.9 6.2 10.8 7.6 14.8 9.6 18.4 10.7 8.4 7.3 140.8 18.8 27.6 18.0 3.3 7.3 33.3 7.4 61.5 31.2 22.1 36.7 16.9 29.7 6.1 39.5 51.8 3.4 131.2 3.1 5.6 2.8 3.1 27.7 4.1 2.0 2.4 14.1 3.3 142.8 4.2 3.3 46.4 14.5 20.1 10.7 25.4 17.8 18.7 16.9 14.8 28.2 9.4 WARS2 TrpRS ENSG00000116874 "Tryptophanyl tRNA synthetase 2, mitochondrial" Q9UGM6 1 119031216-119140671 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069692 Enhanced Supported "Plasma membrane,Mitochondria" Mitochondria "Plasma membrane" "HPA069692: " "unprognostic (1.00e-1)" "unprognostic (2.25e-1)" "unprognostic (2.03e-1)" "unprognostic (5.64e-2)" "unprognostic (3.42e-1)" "unprognostic (7.05e-2)" "unprognostic (7.73e-3)" "unprognostic (3.72e-1)" "unprognostic (2.14e-2)" "unprognostic (1.17e-2)" "unprognostic (3.96e-2)" "unprognostic (6.76e-3)" "prognostic favourable (1.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.83e-1)" "unprognostic (9.88e-3)" "unprognostic (4.71e-2)" 17.3 16.7 6.8 11.7 8.3 2.8 14.6 7.5 8.7 12.9 11.2 7.7 7.6 12.3 13.5 10.4 13.4 14.9 8.8 12.1 6.2 6.1 15.3 14.9 9.2 12.4 6.4 6.1 14.7 17.8 15.1 12.3 14.9 8.3 14.1 12.7 11.3 10.5 10.4 12.2 10.0 13.1 9.0 5.4 9.9 11.2 6.9 6.1 11.6 12.8 13.2 14.2 14.3 10.4 7.2 9.0 0.5 6.9 5.3 7.4 4.9 10.2 4.5 6.0 6.3 7.7 17.4 6.5 5.8 8.2 6.1 7.3 11.2 4.7 15.1 9.4 9.2 6.9 10.8 9.8 9.3 8.1 14.1 7.1 12.0 10.7 15.7 11.5 4.1 13.3 7.6 8.8 16.1 9.0 11.1 11.0 11.2 11.9 6.8 6.7 8.1 9.2 5.0 20.0 7.6 16.5 14.3 8.9 5.4 9.0 12.6 13.0 5.6 9.0 6.9 6.6 8.0 12.4 10.9 5.3 3.6 6.7 8.1 9.7 12.2 0.0 6.9 0.5 5.1 4.9 7.4 6.6 5.4 6.7 9.0 7.2 6.5 6.2 0.3 5.3 3.0 4.5 6.0 4.9 6.8 8.3 7.5 8.7 6.2 6.1 6.4 6.1 8.3 6.1 WDYHV1 "C8orf32, FLJ10204" ENSG00000156795 "WDYHV motif containing 1" Q96HA8 8 123416725-123467230 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024823, HPA053680" Approved Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA024823: AB_1845773, HPA053680: " "unprognostic (9.97e-2)" "unprognostic (4.82e-2)" "unprognostic (3.48e-1)" "prognostic unfavourable (4.93e-5)" "unprognostic (1.69e-1)" "unprognostic (5.00e-2)" "prognostic unfavourable (3.47e-4)" "unprognostic (1.93e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.81e-2)" "unprognostic (1.26e-1)" "unprognostic (5.39e-2)" "unprognostic (7.46e-2)" "unprognostic (2.37e-1)" 10.5 15.5 13.2 7.9 13.6 6.3 17.2 14.3 16.8 14.5 9.9 13.9 10.7 5.8 11.2 12.0 10.2 9.8 8.8 24.8 12.8 19.8 13.6 9.1 8.6 11.4 17.0 10.8 20.4 21.3 9.0 12.8 8.2 16.2 13.5 9.5 9.7 8.3 12.5 19.2 9.8 5.4 13.0 17.0 7.9 10.0 17.5 15.6 5.3 14.4 9.1 11.3 10.1 9.1 5.9 7.2 8.7 7.5 13.1 9.2 5.5 9.1 10.8 12.7 6.7 5.5 12.6 5.7 7.6 6.7 7.2 9.2 6.4 6.1 7.3 6.9 5.3 5.3 8.1 8.8 9.7 17.2 7.1 7.9 5.2 8.7 7.8 3.0 3.4 8.5 5.4 9.6 11.8 7.2 5.9 10.1 10.6 28.6 8.8 6.2 5.1 7.4 5.1 8.0 5.8 9.7 8.1 6.5 14.1 7.8 39.8 12.1 6.6 3.3 3.9 9.6 15.1 7.1 9.2 7.6 15.4 9.0 7.8 4.6 6.0 8.7 6.3 2.5 7.8 7.5 8.4 5.2 8.4 7.3 7.2 5.9 6.5 7.4 1.8 13.1 4.0 4.6 9.2 5.5 13.2 13.6 14.3 16.8 12.8 19.8 17.0 10.8 16.2 15.6 WEE1 WEE1A ENSG00000166483 "WEE1 G2 checkpoint kinase" P30291 11 9573681-9593457 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004619, HPA068845" Approved Approved Nucleoli Nucleoli "CAB004619: AB_628447, HPA068845: " "unprognostic (6.04e-2)" "unprognostic (1.90e-3)" "unprognostic (1.09e-2)" "unprognostic (9.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-2)" "unprognostic (3.79e-3)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (1.79e-2)" "unprognostic (3.21e-3)" "unprognostic (3.73e-1)" "prognostic unfavourable (5.19e-4)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (2.08e-1)" "unprognostic (3.80e-1)" 6.9 3.5 2.0 26.1 2.1 6.6 27.4 5.3 1.6 12.8 18.0 2.5 15.4 3.7 21.9 14.3 22.1 12.4 20.2 23.0 2.0 2.2 6.8 19.3 10.2 10.9 1.8 1.2 11.1 4.4 4.9 6.1 42.7 4.7 17.0 4.7 5.9 12.8 17.8 12.0 33.3 10.4 22.9 2.4 8.0 12.5 28.3 2.0 35.9 12.0 26.8 26.4 19.8 14.7 8.5 0.1 6.4 0.0 2.1 7.8 0.6 14.2 5.5 21.2 11.7 18.6 9.3 42.0 17.6 13.6 9.9 9.8 10.1 17.5 33.4 6.6 7.7 17.3 14.5 6.8 12.7 11.9 11.9 13.1 8.9 6.7 2.0 19.8 13.1 3.1 7.4 4.6 16.4 6.1 21.3 23.3 17.2 3.4 20.2 10.7 31.9 6.3 19.5 16.6 7.2 7.8 30.1 7.9 10.5 11.9 14.1 8.6 8.9 9.5 7.0 17.8 12.5 7.2 14.1 5.5 16.3 44.2 7.6 10.9 12.5 0.0 0.0 6.4 2.0 0.0 0.2 8.5 2.0 3.3 0.1 3.6 0.1 1.6 0.1 2.1 0.0 0.1 7.8 0.6 2.0 2.1 5.3 1.6 2.0 2.2 1.8 1.2 4.7 2.0 WEE2 FLJ16107 ENSG00000214102 "WEE1 homolog 2" P0C1S8 7 141708353-141731271 "Enzymes, Predicted intracellular proteins" Meiosis "Kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "CACO-2: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA027418, HPA054280" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA027418: AB_10603144, HPA054280: " "unprognostic (6.35e-2)" "unprognostic (1.47e-1)" "unprognostic (1.89e-1)" "unprognostic (3.18e-1)" "unprognostic (2.33e-1)" "unprognostic (4.00e-2)" "unprognostic (2.90e-1)" "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (3.02e-2)" "unprognostic (2.61e-1)" "unprognostic (1.76e-2)" "unprognostic (1.73e-1)" "unprognostic (3.25e-2)" "unprognostic (2.66e-1)" "unprognostic (6.07e-2)" "unprognostic (2.88e-3)" 0.6 0.1 0.5 0.3 1.0 0.0 0.4 0.8 0.6 0.6 0.1 0.0 0.7 0.0 1.3 0.7 1.6 1.3 0.5 0.6 1.3 0.1 0.3 1.6 0.6 1.2 1.1 0.0 1.0 0.0 0.3 0.0 0.9 0.0 0.7 2.8 0.4 0.0 0.8 0.4 0.8 1.3 2.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 1.3 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.0 0.4 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 1.0 0.3 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.5 1.6 1.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.2 0.1 1.7 1.1 0.5 0.0 0.3 0.7 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.4 0.6 0.0 0.1 0.1 0.6 0.0 0.5 0.0 0.0 0.2 0.0 WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752593-911452 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein kinase inhibitor, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol Cytosol "HPA046541: , HPA059157: " "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (4.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (7.68e-2)" "unprognostic (1.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (9.67e-4)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (4.38e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" 30.0 12.4 49.3 19.1 47.5 28.9 45.4 22.5 36.7 21.2 12.6 42.6 10.6 8.5 15.9 19.4 45.5 16.9 16.5 38.5 53.7 36.4 45.6 18.0 33.0 34.3 62.3 27.1 18.5 11.3 29.1 12.7 20.3 41.4 17.1 14.3 12.0 15.4 20.3 43.4 31.3 10.3 22.3 82.8 16.9 15.7 23.8 38.8 23.9 16.7 17.4 24.5 18.9 26.5 3.7 2.6 10.9 7.1 2.1 5.2 1.9 14.2 27.0 35.7 3.3 25.8 24.8 13.6 14.2 17.1 15.4 14.4 15.2 16.3 20.1 5.0 30.5 10.8 24.1 16.4 21.7 34.8 14.4 44.9 35.9 13.1 18.9 24.2 19.6 19.2 25.0 25.5 45.8 20.8 20.4 48.6 23.3 13.1 43.5 4.1 29.1 6.5 20.8 39.6 5.4 22.2 30.9 10.4 12.2 33.2 21.5 9.6 23.7 24.9 23.0 19.1 22.2 26.8 20.9 7.4 12.3 30.5 18.2 12.8 15.5 0.9 2.7 2.6 3.8 4.0 5.2 3.0 4.3 3.6 2.6 3.7 2.3 4.1 10.9 2.1 7.1 1.7 4.9 1.9 49.3 47.5 22.5 36.7 53.7 36.4 62.3 27.1 41.4 38.8 WNK2 "KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43" ENSG00000165238 "WNK lysine deficient protein kinase 2" Q9Y3S1 9 93184916-93320572 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.9;pancreas: 18.3;salivary gland: 19.5;skeletal muscle: 23.7" "Cell line enhanced" "Detected in many" "Daudi: 11.2;Hep G2: 18.4;SCLC-21H: 23.4" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 5 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015555, HPA016519, CAB017813" Enhanced Approved Cytosol Cytosol "CAB017813: , HPA015555: AB_2669218, HPA016519: AB_2669380" "unprognostic (5.02e-2)" "unprognostic (1.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" "unprognostic (1.79e-3)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.31e-3)" "unprognostic (2.23e-1)" "unprognostic (4.48e-3)" "unprognostic (6.51e-2)" "unprognostic (1.44e-1)" "unprognostic (4.38e-4)" "unprognostic (1.62e-1)" 0.0 0.7 3.9 0.9 3.8 0.0 1.2 9.5 7.2 0.7 7.5 7.4 1.3 1.5 2.1 6.6 0.1 21.9 4.0 4.2 0.0 0.0 0.0 0.0 2.6 0.0 18.3 0.8 7.5 0.9 4.9 4.8 19.5 5.5 23.7 3.0 6.2 1.6 1.1 0.5 3.0 1.5 0.0 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 0.3 0.0 4.4 4.0 2.8 8.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 1.6 0.1 11.2 1.5 0.0 0.2 6.4 0.0 0.0 0.0 7.4 0.0 3.5 18.4 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 5.8 0.1 0.1 7.1 0.2 0.0 0.0 9.1 0.0 0.6 23.4 9.2 1.4 6.3 0.6 0.8 1.3 0.1 0.0 3.1 0.1 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.0 WNK3 PRKWNK3 ENSG00000196632 "WNK lysine deficient protein kinase 3" Q9BYP7 X 54192823-54358642 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 31.6;testis: 26.7" "Cell line enhanced" "Detected in some" "AF22: 5.8;AN3-CA: 4.4;HAP1: 6.7;NTERA-2: 11.9;SiHa: 5.8;U-2 OS: 5.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 1.9" "Group enriched" "Detected in many" 10 "B-cells: 1.1;T-cells: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077678 Approved Approved Vesicles Vesicles "HPA077678: " "unprognostic (1.86e-1)" "unprognostic (1.68e-3)" "unprognostic (2.44e-1)" "unprognostic (7.87e-5)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (1.85e-2)" "unprognostic (3.32e-2)" "unprognostic (3.38e-1)" "unprognostic (3.03e-2)" "unprognostic (5.78e-4)" "unprognostic (2.22e-1)" "unprognostic (2.64e-2)" "unprognostic (5.61e-2)" "unprognostic (9.99e-2)" "unprognostic (7.63e-2)" "unprognostic (8.74e-2)" 0.9 5.0 3.9 0.9 4.3 0.8 1.7 3.0 3.6 1.5 0.7 1.7 13.9 1.0 1.3 31.6 1.1 1.8 1.1 1.5 3.9 3.4 2.8 8.7 0.9 1.0 2.3 3.0 5.7 0.9 2.2 14.0 1.2 3.9 2.2 0.7 1.3 1.2 4.8 0.7 0.9 0.7 1.5 3.3 1.0 1.2 26.7 3.5 0.0 1.7 0.0 0.8 1.3 1.9 1.1 0.0 0.1 0.0 0.1 1.9 0.1 0.0 0.0 5.8 4.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.7 0.1 0.2 0.0 1.2 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.9 0.0 2.8 0.8 0.0 1.1 0.2 1.9 1.8 5.8 0.0 0.7 0.5 0.0 0.3 0.0 5.2 0.0 1.2 0.0 4.0 0.0 1.6 0.0 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 1.1 1.9 0.4 0.1 0.1 0.0 0.0 0.0 0.1 3.9 4.3 3.0 3.6 3.9 3.4 2.3 3.0 3.9 3.5 WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780678-42796936 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.1;ovary: 14.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 19.4;K-562: 21.7;TIME: 21.0;WM-115: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in single" "memory CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" 1.1 0.0 0.8 5.8 0.2 0.0 2.6 0.6 0.3 0.7 12.9 0.4 0.4 2.1 0.2 2.8 8.7 0.5 1.0 0.2 2.6 0.0 28.1 0.2 0.4 0.1 0.1 0.3 14.6 1.0 0.0 2.4 0.0 1.7 11.1 11.7 12.2 1.4 1.2 0.0 0.5 3.3 0.4 0.8 0.1 2.6 0.4 0.2 0.0 0.0 0.2 2.0 0.3 0.4 0.4 0.0 0.0 0.3 0.0 1.0 0.0 1.2 0.6 0.2 0.0 0.2 0.1 2.9 7.2 2.8 2.7 0.8 0.4 0.5 0.2 4.3 19.4 0.0 0.1 0.2 4.7 0.4 0.9 0.0 0.0 2.8 4.6 0.0 0.4 2.5 0.4 3.9 1.2 0.2 21.7 0.7 0.0 0.6 0.0 0.5 0.2 4.9 0.3 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.9 1.4 1.5 21.0 0.2 1.9 0.2 0.1 3.5 3.0 0.6 0.0 1.2 14.1 0.0 0.3 0.0 0.0 0.0 0.7 0.4 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.6 0.3 2.6 0.0 0.1 0.3 1.7 0.2 WRN "RECQ3, RECQL2" ENSG00000165392 "Werner syndrome RecQ like helicase" Q14191 8 31033801-31173769 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028661 Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA028661: AB_10602255" "unprognostic (8.73e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-3)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-2)" "unprognostic (6.63e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-2)" "unprognostic (2.66e-1)" 10.1 9.2 5.6 8.5 6.6 15.6 11.1 10.7 7.3 14.2 8.0 7.7 7.7 5.5 24.4 8.8 7.6 9.7 6.9 7.0 5.9 4.0 5.1 7.7 7.2 6.7 8.2 5.3 12.0 9.9 7.8 28.1 8.5 7.0 8.6 7.8 8.3 10.8 7.8 7.7 10.2 7.0 12.1 14.9 8.9 8.3 10.4 7.3 11.8 7.9 6.3 9.3 10.8 8.7 3.9 2.7 1.3 1.9 2.9 6.2 1.6 6.4 6.3 13.1 8.3 7.8 12.5 8.3 7.3 7.1 8.9 9.3 4.0 3.9 15.1 6.7 7.3 3.3 8.1 5.2 13.4 4.2 6.9 15.4 6.0 3.3 9.8 9.1 5.7 9.1 5.8 8.5 10.2 8.6 24.3 9.6 8.2 4.1 18.9 4.4 11.2 4.6 10.9 9.9 6.0 3.7 7.0 2.8 7.5 8.8 5.0 6.9 3.5 4.5 13.7 9.7 6.0 5.0 6.1 2.5 2.7 19.0 7.2 7.2 6.6 1.2 1.9 1.3 3.3 1.9 6.2 3.9 3.8 3.3 2.7 3.5 2.5 3.2 0.5 2.9 0.8 2.0 2.8 1.6 5.6 6.6 10.7 7.3 5.9 4.0 8.2 5.3 7.0 7.3 WRNIP1 "bA420G6.2, FLJ22526, WHIP" ENSG00000124535 "Werner helicase interacting protein 1" Q96S55 6 2765414-2786952 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031752, HPA031753" Enhanced Approved Nucleoplasm Nucleoplasm "HPA031752: AB_10603004, HPA031753: AB_2674028" "unprognostic (5.52e-2)" "unprognostic (5.95e-2)" "unprognostic (6.83e-3)" "unprognostic (8.35e-3)" "unprognostic (7.66e-2)" "unprognostic (7.10e-2)" "unprognostic (5.63e-3)" "unprognostic (3.40e-2)" "unprognostic (1.39e-2)" "unprognostic (1.73e-2)" "unprognostic (1.81e-1)" "unprognostic (6.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.37e-1)" "unprognostic (2.61e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" 15.4 23.1 29.9 19.8 32.1 31.2 22.4 42.5 33.5 22.2 21.9 23.3 25.7 17.7 19.8 29.7 32.8 28.0 24.7 28.8 30.9 30.1 23.3 25.8 21.2 23.4 27.4 26.2 23.2 37.4 39.2 31.2 32.3 21.3 22.5 22.6 23.9 34.6 22.0 29.0 27.8 19.6 18.5 20.2 20.7 19.3 24.6 24.2 34.1 31.6 36.0 25.3 18.8 29.2 3.4 4.2 9.1 2.8 3.7 6.5 2.3 31.0 15.6 15.9 26.1 16.9 14.6 21.2 14.3 20.1 26.3 26.3 24.6 14.5 27.9 38.9 18.4 24.2 26.0 28.7 25.8 27.8 28.6 29.1 17.7 38.4 19.3 18.3 20.2 14.8 23.5 24.1 26.3 33.2 22.2 10.1 19.1 30.3 27.0 33.2 13.6 19.4 21.6 23.3 28.2 27.9 19.2 48.1 13.7 16.8 17.2 33.2 22.1 20.6 18.0 19.8 14.9 17.1 34.4 13.0 22.7 21.6 7.7 19.9 26.7 9.1 2.6 3.4 6.5 2.8 2.1 3.4 4.7 4.8 2.1 2.4 5.5 5.2 1.1 3.7 1.4 4.2 6.5 2.3 29.9 32.1 42.5 33.5 30.9 30.1 27.4 26.2 21.3 24.2 WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342738-86478420 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: AB_10602587" "unprognostic (3.89e-1)" "unprognostic (6.63e-2)" "unprognostic (3.81e-2)" "unprognostic (7.91e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.24e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "prognostic favourable (5.45e-5)" "unprognostic (2.35e-1)" "unprognostic (4.63e-1)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" 15.4 9.1 9.7 15.6 14.1 5.2 20.9 8.5 9.5 11.5 16.9 7.5 21.1 8.7 11.9 19.3 11.7 7.2 22.0 40.7 8.7 8.5 16.9 37.2 10.2 15.9 10.0 7.8 10.1 11.3 40.7 7.3 15.6 12.7 17.8 11.3 8.9 11.8 9.4 58.0 13.8 13.0 18.4 9.9 19.1 11.4 10.4 9.5 11.1 11.2 18.0 12.5 14.5 12.3 3.7 2.6 6.5 2.8 2.9 10.4 2.3 22.9 10.8 7.5 5.3 9.4 9.3 6.9 8.4 8.9 6.7 8.0 7.6 14.1 9.9 5.7 14.3 19.7 10.5 13.4 11.6 12.2 8.4 11.3 9.6 17.8 6.9 4.5 5.9 8.4 17.2 7.3 13.6 29.4 5.9 11.6 11.3 11.4 10.8 3.4 4.5 12.2 7.1 9.0 8.7 15.0 17.6 2.2 5.2 8.3 42.1 8.9 12.5 4.2 33.8 10.0 11.9 10.6 4.3 13.8 8.4 10.1 12.4 0.8 7.6 6.5 2.8 4.8 7.2 2.4 6.0 3.7 8.7 7.1 1.9 3.6 10.4 6.3 1.7 2.9 2.8 2.6 8.0 2.3 9.7 14.1 8.5 9.5 8.7 8.5 10.0 7.8 12.7 9.5 XDH "XO, XOR" ENSG00000158125 "Xanthine dehydrogenase" P47989 2 31334321-31414715 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 78.6;liver: 32.5" "Cell line enhanced" "Detected in some" "BJ: 6.1;HBEC3-KT: 15.0;hTERT-HME1: 23.9;U-251 MG: 6.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062641, HPA069323" Supported Uncertain Nucleoplasm,Nucleoli "Intracellular and membrane" Nucleoplasm Nucleoli "HPA062641: , HPA069323: " "unprognostic (8.58e-2)" "unprognostic (4.07e-2)" "unprognostic (1.34e-2)" "unprognostic (1.79e-1)" "unprognostic (2.08e-2)" "unprognostic (7.06e-2)" "unprognostic (4.38e-3)" "unprognostic (7.48e-3)" "unprognostic (3.55e-1)" "unprognostic (3.60e-2)" "unprognostic (3.95e-3)" "unprognostic (3.51e-2)" "unprognostic (1.24e-6)" "unprognostic (2.25e-1)" "unprognostic (5.25e-2)" "unprognostic (2.54e-1)" "prognostic favourable (8.73e-6)" 0.2 0.2 0.2 2.4 0.2 0.0 17.8 0.2 0.2 2.6 17.9 0.1 0.0 20.1 0.3 6.3 9.3 0.2 1.8 0.2 0.1 0.2 0.4 32.5 0.2 0.0 0.2 0.0 0.2 0.4 0.0 1.5 3.7 0.1 1.2 4.2 0.1 20.9 0.0 0.7 1.0 78.6 0.1 0.2 0.2 1.3 0.2 0.0 0.2 0.3 2.4 6.1 1.8 1.1 0.7 0.3 1.0 0.6 0.7 0.5 0.0 1.5 0.3 0.0 0.0 0.0 0.1 0.1 6.1 3.5 0.7 1.1 0.2 1.7 0.0 1.2 0.2 3.2 0.0 15.0 0.8 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.3 0.9 23.9 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.3 0.1 0.0 1.1 3.3 4.4 3.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.9 1.9 0.1 6.5 1.9 0.1 0.0 0.2 0.0 0.0 0.5 0.6 0.2 0.2 0.2 0.4 0.1 0.3 0.3 0.0 0.7 0.2 0.5 1.0 0.7 0.2 0.3 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.0 0.1 0.0 XIAP "API3, BIRC4, hILP" ENSG00000101966 "X-linked inhibitor of apoptosis" P98170 X 123859724-123913979 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway, Wnt signaling pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB009203, HPA042428" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009203: AB_2257167, HPA042428: " "prognostic unfavourable (9.21e-4)" "unprognostic (8.43e-2)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.40e-1)" "unprognostic (9.41e-2)" "unprognostic (1.95e-2)" "unprognostic (8.51e-2)" "unprognostic (9.17e-2)" "unprognostic (3.90e-2)" "unprognostic (7.50e-2)" "unprognostic (4.41e-2)" "unprognostic (3.15e-3)" "unprognostic (8.21e-3)" "unprognostic (2.26e-1)" "unprognostic (4.99e-2)" "unprognostic (4.65e-2)" 17.4 14.4 20.0 18.1 20.2 12.0 15.9 21.3 18.9 17.2 19.4 14.5 22.9 16.1 17.4 17.0 18.9 12.6 14.7 15.7 18.9 22.1 19.8 19.4 16.5 15.5 18.8 14.6 13.9 19.7 36.6 26.1 18.2 15.9 15.6 16.8 16.9 14.6 22.9 21.5 14.2 23.4 17.0 19.0 15.8 16.2 7.0 12.3 13.9 24.3 11.4 14.0 15.4 20.5 5.7 4.3 11.1 3.9 3.3 5.5 1.9 11.5 9.9 7.8 6.7 9.2 11.9 10.2 12.6 9.4 6.9 5.9 4.4 13.6 10.8 18.7 10.7 4.3 11.5 7.9 12.7 11.2 6.3 7.3 8.3 6.7 11.7 13.2 15.2 8.2 12.3 11.4 14.7 9.5 11.5 12.5 13.3 12.0 7.3 6.4 6.4 7.8 7.9 9.1 11.4 10.4 16.8 5.3 7.7 17.2 10.0 10.1 6.1 6.5 11.7 0.3 4.7 20.6 14.0 10.5 10.5 12.0 14.2 9.4 8.7 11.1 2.6 3.5 5.0 2.3 4.7 4.6 3.8 5.5 1.4 5.7 4.4 3.0 8.2 3.3 3.9 4.3 2.5 1.9 20.0 20.2 21.3 18.9 18.9 22.1 18.8 14.6 15.9 12.3 XPNPEP1 "XPNPEP, XPNPEPL, XPNPEPL1" ENSG00000108039 "X-prolyl aminopeptidase 1" Q9NQW7 10 109864766-109923553 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025196, HPA030419, HPA030420, HPA030422" Supported Enhanced Cytosol 760000 Cytosol "CAB025196: , HPA030419: AB_10598917, HPA030420: AB_10611523, HPA030422: AB_10601783" "unprognostic (3.17e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (2.46e-1)" "unprognostic (2.01e-3)" "prognostic unfavourable (2.12e-5)" "unprognostic (8.03e-2)" "unprognostic (2.10e-2)" "unprognostic (1.88e-1)" "unprognostic (4.89e-2)" "unprognostic (7.61e-2)" "unprognostic (2.43e-2)" "unprognostic (1.34e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (5.18e-2)" 16.6 14.7 13.4 16.1 18.9 12.8 13.6 14.8 22.2 15.7 20.6 19.5 14.1 33.2 17.5 16.1 17.8 15.8 20.3 17.8 13.7 11.4 18.3 21.0 14.8 14.9 13.8 14.0 17.8 46.0 14.9 15.9 19.0 17.2 16.0 26.9 15.6 19.6 11.3 18.5 20.4 38.6 18.6 11.9 18.0 16.8 15.1 12.0 9.9 15.7 15.2 24.2 14.1 13.8 5.5 24.0 10.0 21.0 14.7 10.6 13.4 25.3 11.2 17.9 24.4 29.2 27.5 13.7 14.2 28.9 21.3 23.1 21.7 21.9 36.3 12.3 21.8 13.5 14.2 17.5 20.9 10.7 13.6 24.2 7.3 9.0 20.4 18.8 20.2 27.0 10.9 23.4 20.8 34.9 7.8 11.6 27.0 8.6 13.4 11.7 7.0 12.1 15.1 36.1 6.5 27.0 8.0 5.4 20.8 12.3 7.8 23.6 9.5 17.6 17.9 8.7 11.4 13.7 12.4 19.8 9.6 31.0 20.5 26.4 6.8 10.0 13.7 5.6 10.6 21.0 7.3 5.5 7.0 9.5 24.0 4.8 5.0 6.6 1.1 14.7 17.5 18.8 7.5 13.4 13.4 18.9 14.8 22.2 13.7 11.4 13.8 14.0 17.2 12.0 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738974-129769538 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "intestine: 145.6;kidney: 49.7" "Cell line enhanced" "Detected in some" "ASC diff: 6.2;ASC TERT1: 32.6;HSkMC: 16.5" "Group enriched" "Detected in many" 6 "colorectal cancer: 5.3;liver cancer: 18.3;stomach cancer: 3.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 7.3;intermediate monocyte: 2.1;MAIT T-cell: 2.2;memory CD4 T-cell: 2.4;memory CD8 T-cell: 4.8;naive CD8 T-cell: 3.6;non-classical monocyte: 4.4;T-reg: 2.2" "Group enriched" "Detected in many" 7 "monocytes: 4.4;T-cells: 7.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" 8900000 "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 4.7 0.5 0.0 1.1 0.1 0.0 3.2 0.0 0.1 1.7 57.4 0.1 0.8 37.0 1.2 1.7 4.2 3.4 1.3 2.6 0.0 0.0 49.7 8.0 1.0 1.2 0.0 0.0 3.5 0.9 0.0 0.0 0.6 0.1 3.6 2.0 0.7 0.7 0.3 1.6 2.1 145.6 2.5 0.1 0.2 1.7 1.2 0.0 0.1 0.9 1.4 0.3 4.0 10.7 0.4 0.8 0.2 4.4 0.0 7.3 1.3 0.0 0.0 0.4 0.0 6.2 32.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.8 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 7.3 2.1 2.2 0.0 2.4 4.8 0.3 0.4 0.7 3.6 0.2 0.0 4.4 0.8 2.2 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 XPNPEP3 "APP3, ICP55, NPHPL1" ENSG00000196236 "X-prolyl aminopeptidase 3" Q9NQH7 22 40857077-40932815 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000527 Approved "HPA000527: AB_1079266" "prognostic unfavourable (8.19e-4)" "unprognostic (6.77e-2)" "unprognostic (3.22e-3)" "unprognostic (5.03e-3)" "unprognostic (6.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (2.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (6.69e-2)" "unprognostic (8.00e-3)" "unprognostic (2.49e-1)" "prognostic unfavourable (6.10e-4)" "unprognostic (1.24e-1)" 8.2 13.6 7.5 5.8 9.2 4.7 9.7 5.2 7.8 7.3 6.1 10.8 11.6 32.3 10.7 12.3 7.2 9.4 10.5 11.2 7.6 7.1 9.8 19.0 6.6 10.6 7.9 6.1 10.7 10.5 8.0 15.0 6.1 10.7 7.3 6.2 9.3 8.5 13.6 12.0 11.5 20.9 7.1 9.3 7.7 6.8 18.9 8.2 11.5 9.1 7.3 8.8 12.6 8.2 5.9 6.0 6.4 10.0 1.2 4.4 4.0 3.2 4.7 3.2 7.0 9.0 6.0 2.2 4.1 3.1 2.3 2.3 3.9 2.1 6.5 2.3 7.9 7.6 6.0 3.2 3.4 3.9 12.4 4.2 9.3 7.3 4.1 7.3 0.7 5.2 5.0 7.2 4.3 4.0 3.5 5.9 4.8 5.0 3.5 3.9 1.9 9.6 4.9 4.3 3.7 6.4 4.4 2.8 2.5 4.0 6.1 3.8 7.1 3.3 4.0 4.7 4.1 4.3 2.4 5.5 4.2 7.9 7.2 9.6 3.2 4.0 4.4 4.4 3.4 3.9 1.8 5.9 2.1 2.2 3.1 3.7 4.4 3.3 6.4 1.2 10.0 6.0 3.0 4.0 7.5 9.2 5.2 7.8 7.6 7.1 7.9 6.1 10.7 8.2 XYLB "FLJ10343, FLJ12539" ENSG00000093217 Xylulokinase O75191 3 38346760-38421348 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Xylose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 34.0" "Cell line enhanced" "Detected in many" "Hep G2: 21.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 6.4;monocytes: 3.6;T-cells: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037863, HPA038415" Uncertain Approved "Nuclear speckles" "Nuclear speckles" "HPA037863: AB_10672729, HPA038415: AB_10672592" "unprognostic (2.48e-1)" "unprognostic (9.72e-2)" "unprognostic (3.42e-2)" "unprognostic (6.25e-2)" "unprognostic (7.52e-2)" "unprognostic (5.19e-2)" "unprognostic (5.82e-2)" "unprognostic (1.26e-3)" "unprognostic (6.55e-2)" "unprognostic (2.22e-1)" "unprognostic (6.91e-3)" "unprognostic (4.63e-2)" "prognostic favourable (8.57e-4)" "unprognostic (3.26e-1)" "unprognostic (2.06e-1)" "unprognostic (5.78e-2)" "unprognostic (3.37e-2)" 2.3 3.2 2.7 1.9 3.4 2.5 3.0 10.3 4.7 2.7 5.9 2.3 1.6 5.8 3.7 3.6 3.1 1.9 2.5 1.5 1.8 1.8 11.3 34.0 1.8 1.3 1.9 3.3 2.8 6.1 1.2 3.1 1.4 4.1 2.1 5.1 3.0 7.1 1.8 1.3 1.9 9.8 3.6 2.0 1.6 3.7 2.1 1.6 2.3 1.5 1.8 1.3 2.7 2.9 0.4 6.4 1.1 3.6 0.9 3.9 1.1 3.0 5.7 2.1 4.6 2.9 3.2 5.1 4.3 1.6 3.9 3.8 7.7 3.2 2.7 1.1 5.4 2.1 6.2 2.5 4.2 3.8 4.8 5.3 4.4 21.0 1.8 7.5 5.7 2.1 4.3 5.2 2.1 3.5 14.3 5.2 3.7 1.6 6.4 1.0 3.0 6.9 3.2 4.2 3.8 0.4 4.7 2.6 2.4 2.5 11.5 9.3 5.5 4.3 1.3 7.3 5.7 11.1 1.8 2.8 4.5 7.3 3.9 6.3 5.3 0.5 2.2 0.7 1.5 3.6 1.0 0.3 1.2 0.8 6.4 0.4 1.5 1.5 1.1 0.9 2.9 1.3 3.9 1.1 2.7 3.4 10.3 4.7 1.8 1.8 1.9 3.3 4.1 1.6 XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470881 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.6" "Cell line enhanced" "Detected in many" "ASC diff: 18.8;U-2197: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" 30000 "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" 5.7 5.9 6.3 21.6 3.1 5.9 7.0 3.8 6.7 8.0 7.4 1.4 0.9 3.9 7.4 3.0 4.9 3.2 4.4 3.8 6.3 4.2 1.9 0.9 2.9 7.5 4.3 2.2 5.5 2.6 0.2 1.8 5.4 2.6 4.4 4.9 3.4 2.6 4.3 1.3 4.1 4.7 5.1 3.9 6.3 3.2 3.0 2.1 4.6 2.7 6.7 6.6 4.7 4.2 1.2 0.8 1.2 3.6 0.9 0.7 0.5 0.0 0.1 2.6 0.0 18.8 11.7 3.2 8.4 4.3 0.9 0.4 0.1 0.2 2.0 0.0 10.1 0.2 0.0 1.7 1.5 4.0 0.2 2.5 0.0 0.0 0.2 3.6 3.4 4.3 0.2 5.4 0.8 0.0 0.3 7.9 0.9 0.3 0.0 3.9 2.8 0.0 1.2 0.0 0.4 0.0 3.8 0.7 5.1 0.6 2.6 0.5 0.6 2.3 0.0 8.8 1.0 19.3 0.0 8.8 0.5 3.8 9.8 4.1 7.4 0.6 0.6 1.2 0.6 2.5 0.7 1.2 0.5 0.3 0.8 1.2 0.5 0.4 0.3 0.9 3.6 0.2 0.7 0.5 6.3 3.1 3.8 5.3 6.3 4.2 4.3 2.2 2.6 2.1 XYLT2 "PXYLT2, XT-II" ENSG00000015532 "Xylosyltransferase 2" Q9H1B5 17 50346092-50363138 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 53.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016456 Approved "Nuclear bodies,Cytosol" "Secreted to blood" 990000 "Nuclear bodies" Cytosol "HPA016456: AB_1858907" "unprognostic (1.52e-1)" "unprognostic (2.84e-1)" "unprognostic (1.65e-1)" "unprognostic (8.07e-2)" "unprognostic (1.90e-3)" "unprognostic (1.90e-1)" "unprognostic (7.29e-3)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (2.30e-1)" "unprognostic (1.54e-2)" "unprognostic (2.81e-1)" "unprognostic (7.63e-2)" "unprognostic (5.15e-2)" "unprognostic (7.38e-2)" "unprognostic (1.52e-2)" "unprognostic (2.68e-2)" 6.9 8.5 5.8 11.3 10.6 4.1 7.4 10.3 10.9 10.7 9.2 5.4 15.8 10.0 9.6 12.2 8.5 10.4 14.9 9.4 5.3 4.8 9.2 6.1 6.1 10.2 4.7 8.8 11.8 13.5 9.1 5.8 9.0 5.4 12.1 3.9 13.1 12.7 11.7 7.9 15.6 6.9 17.0 3.8 8.4 53.4 5.8 3.7 10.2 9.5 6.7 10.4 11.7 9.0 5.3 4.9 6.6 4.0 7.8 7.8 4.3 9.7 12.5 3.4 2.8 4.8 4.7 8.9 9.1 8.4 8.2 9.3 13.2 7.4 5.1 23.2 8.2 7.5 1.1 12.8 1.7 25.2 8.9 11.4 3.8 5.7 6.6 3.6 6.2 6.4 7.9 6.6 3.1 7.0 2.0 4.3 5.4 12.7 6.6 4.9 3.1 8.8 3.3 10.0 4.2 4.6 5.1 1.8 4.3 6.1 5.8 9.6 27.6 3.5 8.2 18.8 9.6 10.2 8.1 23.4 10.7 1.7 19.8 5.8 5.1 6.6 4.0 3.2 5.9 2.8 6.3 2.9 5.9 7.8 4.9 5.3 6.0 5.3 4.7 7.8 2.5 3.4 5.2 4.3 5.8 10.6 10.3 10.9 5.3 4.8 4.7 8.8 5.4 3.7 YARS "tyrRS, YRS, YTS" ENSG00000134684 "Tyrosyl-tRNA synthetase" P54577 1 32775237-32818153 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017936, HPA018950, HPA018954" Enhanced Enhanced Cytosol 230000 Cytosol "HPA017936: AB_1858916, HPA018950: AB_1858919, HPA018954: AB_1858915" "unprognostic (4.05e-2)" "unprognostic (2.52e-1)" "unprognostic (4.21e-1)" "unprognostic (4.78e-2)" "unprognostic (9.54e-2)" "unprognostic (3.38e-3)" "prognostic unfavourable (6.97e-11)" "unprognostic (5.05e-2)" "unprognostic (6.29e-2)" "unprognostic (1.93e-1)" "unprognostic (1.81e-3)" "unprognostic (4.96e-2)" "prognostic unfavourable (1.02e-11)" "unprognostic (3.57e-3)" "unprognostic (1.02e-1)" "unprognostic (4.94e-2)" "prognostic unfavourable (6.57e-4)" 16.6 36.3 22.8 22.8 40.6 17.4 13.9 26.6 43.1 14.6 17.5 16.3 22.4 17.1 14.2 15.5 24.1 14.4 11.2 15.5 24.9 28.3 14.1 29.6 21.3 23.2 24.9 27.4 21.2 54.8 19.3 13.9 17.5 26.7 12.7 21.9 11.2 23.5 25.7 27.3 16.5 14.9 22.7 22.7 14.6 25.9 20.9 26.0 15.2 30.0 16.8 29.6 17.0 28.0 9.9 17.8 20.9 13.4 36.5 24.3 17.1 28.3 14.8 15.7 37.7 19.5 22.5 16.7 29.4 24.3 24.1 30.8 17.6 19.6 51.7 11.7 30.5 16.7 47.7 34.6 38.2 21.7 18.9 47.3 22.5 16.6 64.2 37.3 28.7 22.2 43.0 38.1 97.1 24.4 52.2 54.8 20.7 14.7 41.8 20.5 28.5 20.6 36.7 15.0 43.5 17.3 14.2 30.3 18.6 16.0 18.8 54.1 18.8 40.7 19.8 14.7 26.2 29.8 24.2 44.3 47.1 48.3 36.7 52.1 40.3 20.9 12.7 6.6 24.3 13.4 23.9 9.9 14.5 22.3 17.8 8.1 10.8 16.5 3.0 36.5 12.4 10.2 15.6 17.1 22.8 40.6 26.6 43.1 24.9 28.3 24.9 27.4 26.7 26.0 YARS2 "CGI-04, FLJ13995, mt-TyrRS" ENSG00000139131 "Tyrosyl-tRNA synthetase 2" Q9Y2Z4 12 32727490-32755902 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038721, HPA057610, HPA074097" Uncertain Supported "Nuclear bodies,Mitochondria" Mitochondria "Nuclear bodies" "HPA038721: AB_10674837, HPA057610: , HPA074097: " "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (2.30e-3)" "unprognostic (1.02e-2)" "unprognostic (2.12e-1)" "unprognostic (5.99e-3)" "prognostic unfavourable (3.19e-5)" "unprognostic (1.41e-2)" "unprognostic (4.98e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-2)" "unprognostic (8.39e-2)" "unprognostic (7.45e-2)" "unprognostic (1.99e-1)" "unprognostic (4.71e-1)" "unprognostic (4.07e-1)" "unprognostic (2.09e-1)" 12.6 15.8 11.0 12.6 15.3 13.9 13.8 11.6 14.9 13.1 11.8 11.5 18.4 9.8 13.3 12.9 17.5 11.3 9.1 12.1 11.9 9.7 12.4 16.3 9.2 15.5 10.8 11.7 13.3 21.0 11.0 16.6 15.9 13.5 12.9 13.7 11.3 17.4 10.0 15.9 12.0 10.8 11.1 12.6 13.3 12.3 12.5 12.6 17.5 12.3 16.0 16.4 13.3 11.8 11.8 9.5 9.4 9.9 12.9 12.7 5.2 9.5 11.5 6.7 8.0 7.4 8.7 21.3 7.3 7.5 9.1 8.9 28.8 12.3 17.3 12.0 7.4 12.4 13.4 19.3 10.3 7.5 20.9 11.4 8.7 16.0 10.7 12.1 6.7 8.1 12.4 8.5 15.6 14.3 16.1 8.0 9.6 7.8 9.0 14.7 37.1 14.2 10.2 14.4 10.2 11.5 13.7 10.4 5.0 11.2 9.8 7.2 18.3 11.0 9.6 8.6 9.2 14.0 12.3 4.8 5.1 18.0 8.0 9.1 7.1 9.4 7.0 4.1 10.1 8.9 10.6 8.8 10.7 10.4 9.5 11.8 11.2 12.7 1.4 12.9 9.9 9.3 9.3 5.2 11.0 15.3 11.6 14.9 11.9 9.7 10.8 11.7 13.5 12.6 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 14.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" 4300000 "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavourable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 26.2 13.1 17.0 9.4 15.6 2.6 47.2 6.7 12.8 15.8 23.8 8.9 13.7 18.2 13.1 17.4 22.0 10.7 14.9 17.9 14.8 12.4 22.6 43.2 23.6 13.7 15.8 6.6 13.2 21.4 16.7 10.7 31.3 16.8 12.2 17.3 6.5 23.7 21.0 10.6 12.3 24.8 18.8 16.8 34.5 15.5 13.6 12.0 8.1 16.8 15.6 7.1 21.9 17.5 0.1 0.1 14.7 0.0 1.0 2.5 0.6 14.2 7.1 22.4 17.5 13.5 16.7 26.4 9.5 19.4 11.2 15.4 16.8 10.5 0.0 10.1 16.1 8.3 20.9 16.8 22.0 0.0 7.1 4.2 7.0 11.7 11.0 3.2 7.6 12.7 18.1 16.9 18.9 37.8 18.4 6.3 15.9 9.8 1.9 4.2 14.2 9.1 2.4 17.6 1.2 16.3 16.9 4.6 5.3 19.6 14.9 12.4 10.3 6.8 32.5 27.7 30.7 20.8 25.5 5.5 2.7 0.8 10.5 4.7 16.4 14.7 0.0 0.9 2.5 0.0 1.6 0.1 0.5 1.4 0.0 0.0 1.2 1.9 0.0 1.0 0.0 0.1 0.1 0.6 17.0 15.6 6.7 12.8 14.8 12.4 15.8 6.6 16.8 12.0 YME1L1 ENSG00000136758 "YME1 like 1 ATPase" Q96TA2 10 27110112-27155266 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066953 Approved Supported "Nuclear bodies,Mitochondria" Mitochondria "Nuclear bodies" "HPA066953: " "unprognostic (2.28e-3)" "unprognostic (3.00e-2)" "unprognostic (1.34e-1)" "unprognostic (7.19e-2)" "unprognostic (8.12e-2)" "unprognostic (2.47e-1)" "prognostic unfavourable (8.25e-6)" "unprognostic (7.08e-2)" "unprognostic (2.91e-1)" "unprognostic (9.24e-2)" "unprognostic (9.43e-3)" "unprognostic (1.64e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (5.53e-2)" "unprognostic (1.44e-2)" "unprognostic (7.09e-2)" 27.8 37.3 22.7 25.0 26.2 41.4 39.2 27.8 27.5 27.6 24.3 15.7 29.8 22.3 29.9 35.9 34.5 25.3 24.4 34.1 23.4 21.5 26.8 45.4 26.9 38.7 19.3 25.5 32.5 33.8 27.8 28.6 33.4 22.0 25.9 26.3 23.3 28.1 31.3 79.0 26.8 25.3 34.6 20.2 26.5 24.7 24.7 20.9 41.7 30.9 32.0 28.9 36.4 28.9 55.6 79.2 73.9 53.0 45.5 56.0 45.9 40.0 30.1 36.1 17.8 35.4 38.1 29.5 39.6 23.2 40.7 46.7 40.7 49.4 42.8 26.4 43.7 38.8 43.3 35.0 45.0 38.8 26.0 40.6 26.9 28.5 38.9 27.7 33.4 31.2 41.4 35.5 36.0 42.5 47.1 43.6 44.9 27.1 51.2 16.0 28.6 14.1 44.3 57.9 39.5 33.2 19.1 27.8 35.6 39.6 30.8 39.7 29.5 34.8 41.6 24.7 34.5 41.4 35.5 21.9 32.1 54.7 35.1 51.5 18.8 53.0 53.0 55.2 55.3 44.8 56.0 51.4 53.8 51.2 42.6 55.6 49.7 51.9 73.9 45.5 47.3 79.2 52.6 45.9 22.7 26.2 27.8 27.5 23.4 21.5 19.3 25.5 22.0 20.9 YOD1 "DKFZp451J1719, DUBA8, OTUD2" ENSG00000180667 "YOD1 deubiquitinase" Q5VVQ6 1 207043849-207052980 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Unfolded protein response" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.7" "Cell line enhanced" "Detected in many" "HEL: 39.4;K-562: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028400, HPA028439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" 40000 "Nucleoplasm, Plasma membrane, Cytosol" "HPA028400: AB_10599854, HPA028439: AB_10600994" "unprognostic (3.69e-2)" "unprognostic (8.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (2.03e-2)" "unprognostic (3.28e-2)" "unprognostic (9.87e-3)" "unprognostic (9.38e-2)" "unprognostic (2.31e-3)" "unprognostic (8.96e-2)" "unprognostic (1.47e-3)" "unprognostic (1.03e-2)" "unprognostic (6.07e-2)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (1.79e-2)" "unprognostic (3.62e-1)" 4.5 4.6 4.0 4.0 5.3 44.7 6.6 4.8 7.5 6.1 3.9 7.6 2.6 4.1 4.0 3.1 24.5 3.7 3.5 5.0 4.0 2.2 4.5 5.2 9.4 4.2 7.1 4.4 3.5 3.6 2.5 5.1 6.3 5.1 3.4 4.0 3.4 9.7 3.0 6.5 14.9 4.8 2.7 8.5 5.2 8.4 5.6 6.9 14.3 5.8 10.0 8.2 5.8 12.3 0.5 1.3 3.9 1.5 1.2 1.8 0.9 5.3 2.8 4.5 2.7 1.6 2.1 8.8 3.5 2.7 2.7 2.7 5.4 5.5 2.8 1.4 2.1 5.9 0.0 4.3 3.0 2.2 4.8 39.4 11.6 2.5 1.5 5.1 13.9 1.5 3.4 2.2 8.4 2.3 27.4 0.0 2.3 0.0 4.5 2.8 4.3 6.4 2.3 0.2 2.0 2.7 6.0 2.3 5.2 5.8 6.7 7.6 2.4 3.6 1.1 2.3 6.1 1.9 4.6 4.5 0.2 4.2 2.7 0.0 1.5 3.9 1.2 2.0 1.1 1.5 1.5 0.4 1.7 0.9 1.3 0.5 1.4 1.8 2.9 1.2 1.0 0.7 0.8 0.9 4.0 5.3 4.8 7.5 4.0 2.2 7.1 4.4 5.1 6.9 YTHDC2 "DKFZp564A186, FLJ10053, FLJ2194" ENSG00000047188 "YTH domain containing 2" Q9H6S0 5 113513683-113595285 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037364, HPA072678" Approved Approved "Nucleoplasm,Nuclear bodies,Cytoplasmic bodies" Nucleoplasm "Nuclear bodies, Cytoplasmic bodies" "HPA037364: AB_10672788, HPA072678: " "unprognostic (2.09e-1)" "unprognostic (2.10e-1)" "prognostic favourable (1.82e-5)" "unprognostic (4.33e-3)" "unprognostic (1.45e-1)" "unprognostic (6.48e-3)" "unprognostic (1.96e-1)" "unprognostic (7.82e-3)" "unprognostic (3.55e-2)" "unprognostic (8.56e-3)" "unprognostic (4.61e-2)" "unprognostic (2.03e-1)" "unprognostic (4.15e-2)" "unprognostic (3.05e-1)" "unprognostic (9.96e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" 15.2 16.3 12.4 18.5 16.8 12.8 15.3 25.2 26.1 16.5 12.7 11.7 9.0 13.6 17.7 14.6 16.1 14.2 12.2 13.0 10.4 10.5 14.3 18.3 12.4 18.7 12.8 10.2 19.9 14.7 35.5 26.2 10.3 18.6 12.8 15.3 14.9 15.5 13.3 18.5 16.5 16.5 13.2 13.7 19.3 13.4 20.5 13.3 19.7 16.2 15.4 18.4 14.7 14.8 9.5 5.5 4.2 4.9 5.7 5.7 1.7 11.1 10.0 13.1 22.0 7.3 9.7 14.3 8.6 9.6 11.1 17.3 7.0 6.3 20.3 6.2 7.2 10.9 15.7 19.3 14.5 8.7 14.2 11.0 18.0 9.4 10.8 8.8 9.8 7.9 7.5 6.9 12.8 15.3 10.8 9.4 9.7 3.7 12.1 6.3 6.0 6.6 5.1 11.3 15.7 9.2 14.8 10.5 8.8 11.6 8.5 8.8 11.9 7.9 13.3 17.0 5.9 8.7 11.7 9.6 12.0 12.7 9.8 10.1 7.2 0.0 4.3 4.2 4.5 2.8 5.3 9.5 5.3 4.8 3.6 8.1 5.7 4.7 1.8 5.7 4.9 5.5 3.7 1.7 12.4 16.8 25.2 26.1 10.4 10.5 12.8 10.2 18.6 13.3 ZADH2 MGC45594 ENSG00000180011 "Zinc binding alcohol dehydrogenase domain containing 2" Q8N4Q0 18 75195108-75209348 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021468, HPA053646" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" Nucleoplasm "Golgi apparatus, Vesicles" "HPA021468: AB_1858932, HPA053646: " "unprognostic (3.22e-2)" "unprognostic (1.03e-2)" "unprognostic (7.14e-2)" "unprognostic (1.13e-1)" "unprognostic (4.79e-1)" "unprognostic (5.11e-3)" "unprognostic (1.15e-1)" "unprognostic (1.49e-1)" "unprognostic (3.62e-3)" "unprognostic (1.42e-1)" "unprognostic (3.05e-2)" "unprognostic (1.48e-1)" "prognostic favourable (1.02e-6)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "prognostic unfavourable (1.94e-4)" "unprognostic (2.23e-1)" 14.1 12.1 15.6 12.5 22.5 12.7 28.1 19.1 24.1 15.5 18.9 10.8 13.6 13.7 12.8 19.0 18.1 13.5 15.7 24.4 17.4 11.3 18.0 23.4 13.3 12.7 12.9 18.4 19.6 19.5 22.4 20.5 26.2 19.3 13.8 21.4 13.5 16.3 14.1 34.5 15.8 24.0 16.9 12.1 15.0 15.5 7.1 11.2 11.2 20.7 15.5 14.5 17.4 15.5 2.7 3.3 12.1 5.2 2.5 4.8 2.3 9.3 6.2 6.6 13.5 10.3 13.4 7.3 16.9 19.7 6.7 8.4 3.8 13.3 6.5 2.7 16.7 12.7 8.2 14.3 4.7 40.6 12.0 14.7 13.7 7.3 7.4 24.7 15.0 14.8 14.3 5.3 12.3 13.7 7.9 24.1 12.7 10.9 6.2 12.2 1.7 14.2 13.3 10.6 21.5 13.0 15.8 12.3 10.1 9.4 9.7 10.7 9.7 12.3 12.1 13.1 10.1 4.1 5.3 3.9 17.1 4.5 8.7 21.5 10.6 1.9 5.0 12.1 4.8 4.2 3.8 2.7 4.1 4.5 3.3 2.5 2.3 3.5 2.7 2.5 5.2 2.5 4.4 2.3 15.6 22.5 19.1 24.1 17.4 11.3 12.9 18.4 19.3 11.2 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713560-97739862 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood: 37.4;lymphoid tissue: 107.1" "Cell line enriched" "Detected in some" 13 "MOLT-4: 61.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 41 "gdT-cell: 37.4;MAIT T-cell: 25.4;memory CD4 T-cell: 19.6;memory CD8 T-cell: 29.2;naive CD4 T-cell: 14.3;naive CD8 T-cell: 21.9;NK-cell: 26.4;T-reg: 19.9" "Group enriched" "Detected in many" 53 "NK-cells: 26.4;T-cells: 37.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002625, HPA003134" Enhanced "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favourable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favourable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favourable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavourable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 2.2 0.5 0.3 18.1 0.6 11.2 1.5 0.7 0.6 1.2 3.7 0.7 0.3 2.9 1.2 1.1 1.7 1.5 2.8 0.9 0.4 0.8 2.2 2.3 5.8 28.1 0.8 0.6 0.9 1.3 0.0 0.7 0.9 0.6 2.1 0.6 1.0 5.5 1.0 0.7 1.0 12.3 0.7 0.7 24.8 3.2 1.4 0.6 107.1 2.5 1.1 20.8 3.0 1.7 0.4 0.2 0.5 0.2 26.4 37.4 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 61.5 0.1 0.0 0.0 2.4 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.1 37.4 0.1 25.4 0.0 19.6 29.2 0.0 0.4 14.3 21.9 0.5 26.4 0.2 0.2 19.9 14.3 0.3 0.6 0.7 0.6 0.4 0.8 0.8 0.6 0.6 0.6 ZCCHC11 "KIAA0191, PAPD3, TUT4" ENSG00000134744 "Zinc finger CCHC-type containing 11" Q5TAX3 1 52408282-52553487 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027412, HPA027973" Supported Supported Nucleoli,Cytosol Cytosol Nucleoli "HPA027412: AB_1852281, HPA027973: AB_10603242" "unprognostic (2.74e-2)" "unprognostic (1.67e-2)" "unprognostic (1.19e-2)" "unprognostic (3.48e-2)" "unprognostic (1.36e-2)" "unprognostic (1.85e-3)" "prognostic unfavourable (9.00e-4)" "unprognostic (2.64e-1)" "unprognostic (5.05e-2)" "unprognostic (3.84e-1)" "unprognostic (6.57e-3)" "unprognostic (3.11e-2)" "unprognostic (5.35e-3)" "unprognostic (2.26e-1)" "unprognostic (1.67e-1)" "unprognostic (7.08e-2)" "unprognostic (2.33e-1)" 13.8 19.1 18.4 25.6 19.0 20.5 18.7 50.9 21.3 22.4 13.3 11.8 16.1 7.7 22.1 22.0 11.5 16.8 14.0 13.5 17.8 16.5 14.2 17.7 13.3 27.4 15.4 14.6 28.3 17.6 34.4 56.0 18.8 16.3 16.1 10.5 12.1 12.6 20.6 44.6 28.1 17.1 20.3 26.6 20.9 12.3 24.9 21.1 31.9 23.9 14.6 25.1 18.3 17.0 23.2 26.0 26.7 4.3 10.3 15.0 2.2 10.4 9.9 24.4 16.5 9.6 12.3 16.9 9.3 13.6 13.6 15.7 10.2 5.5 22.3 11.0 12.9 8.7 18.3 9.8 17.3 18.2 16.7 23.5 12.8 21.2 15.9 25.4 13.4 14.5 21.9 14.5 18.0 9.4 19.1 11.2 11.3 0.1 25.3 18.2 17.7 12.6 22.5 24.8 17.4 14.6 8.6 13.1 13.0 14.3 6.1 13.9 8.5 13.4 7.9 10.6 14.3 9.7 11.3 24.5 32.1 32.1 7.0 13.9 7.6 26.7 4.3 13.8 11.8 1.7 8.8 19.1 12.4 9.5 2.1 23.2 15.0 9.9 16.2 10.3 1.4 26.0 9.3 2.2 18.4 19.0 50.9 21.3 17.8 16.5 15.4 14.6 16.3 21.1 ZCCHC6 "FLJ13409, KIAA1711, PAPD6, TUT7" ENSG00000083223 "Zinc finger CCHC-type containing 6" Q5VYS8 9 86287733-86354454 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 42.1" "Group enriched" "Detected in all" 5 "granulocytes: 42.1;monocytes: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020615, HPA020620" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA020615: AB_1858983, HPA020620: AB_1858984" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.64e-1)" "unprognostic (1.26e-2)" "unprognostic (3.66e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-2)" "unprognostic (2.49e-2)" "unprognostic (4.43e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (3.07e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (1.40e-1)" 11.2 9.3 7.7 22.6 11.2 17.0 17.3 9.7 13.7 10.8 13.5 5.6 12.8 9.4 8.6 8.1 23.1 8.3 10.3 10.1 9.4 5.2 7.4 33.1 16.3 19.5 9.8 5.1 9.0 12.9 9.2 18.6 33.3 9.0 19.3 10.8 4.5 14.0 13.6 12.5 30.9 15.6 9.7 13.6 22.2 11.7 10.3 10.7 23.3 8.7 15.2 16.9 13.7 14.3 4.4 4.3 42.1 15.7 4.5 5.7 2.9 9.8 10.7 6.4 9.2 16.3 24.8 7.8 13.5 13.2 6.0 7.0 4.8 8.8 14.1 12.3 8.9 17.5 7.5 7.6 8.9 16.5 4.0 10.1 11.3 9.0 13.9 11.5 14.8 16.4 16.0 9.5 11.3 10.0 9.5 15.3 16.6 10.6 9.6 7.0 5.2 7.2 4.9 11.1 6.5 10.6 19.4 4.6 3.7 8.2 10.9 4.7 4.1 5.2 15.4 5.7 6.9 10.1 9.2 17.7 13.7 10.5 13.6 6.9 7.5 11.5 7.1 7.1 5.7 9.1 4.9 4.4 3.2 4.1 4.3 4.4 3.7 4.0 42.1 4.5 15.7 2.0 3.0 2.9 7.7 11.2 9.7 13.7 9.4 5.2 9.8 5.1 9.0 10.7 ZDHHC1 "C16orf1, HSU90653, ZNF377" ENSG00000159714 "Zinc finger DHHC-type containing 1" Q8WTX9 16 67394419-67416833 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 13.4;ASC TERT1: 14.9;U-138 MG: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 2.6;intermediate monocyte: 3.6;myeloid DC: 2.4;non-classical monocyte: 3.5" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042531, HPA048659" Uncertain Approved Cytosol Cytosol "HPA042531: , HPA048659: " "unprognostic (8.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.05e-3)" "prognostic favourable (1.25e-6)" "unprognostic (1.68e-2)" "unprognostic (9.33e-2)" "unprognostic (6.03e-2)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" "prognostic favourable (5.99e-4)" "unprognostic (2.17e-1)" "prognostic favourable (1.55e-6)" "unprognostic (2.10e-1)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (5.63e-3)" 9.6 6.3 4.3 3.9 6.6 0.5 10.2 5.3 10.5 16.9 7.4 5.5 7.9 3.8 13.5 16.4 6.3 22.6 14.0 6.2 4.5 3.7 11.2 3.8 7.8 4.9 5.3 3.5 17.1 16.2 11.5 14.0 15.1 6.5 11.6 3.2 11.2 14.7 12.1 8.0 10.8 3.9 9.3 3.3 10.1 6.2 25.7 2.6 0.6 31.3 9.3 4.9 6.9 9.7 0.0 2.4 0.3 3.6 0.0 0.0 0.8 5.0 6.1 1.5 8.1 13.4 14.9 0.0 2.8 11.0 2.9 3.4 0.0 3.2 0.0 1.3 5.1 3.3 0.5 0.5 0.6 1.5 4.6 0.4 0.1 0.4 6.8 0.3 4.3 7.1 6.3 3.1 0.8 3.7 0.0 0.0 2.0 0.5 0.0 0.0 3.0 0.1 0.0 0.1 0.0 4.1 3.1 2.1 7.4 0.5 0.2 6.6 2.1 1.2 4.9 12.9 2.1 6.2 3.4 1.5 0.3 0.0 7.9 0.1 5.3 0.0 2.6 0.0 0.0 3.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.8 4.3 6.6 5.3 10.5 4.5 3.7 5.3 3.5 6.5 2.6 ZDHHC11 "FLJ13153, ZNF399" ENSG00000188818 "Zinc finger DHHC-type containing 11" Q9H8X9 5 795606-850986 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.2" "Cell line enhanced" "Detected in many" "T-47d: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA057886, HPA069008" Uncertain Approved "Lipid droplets" "Lipid droplets" "HPA057886: , HPA069008: " "unprognostic (2.67e-1)" "unprognostic (9.76e-3)" "unprognostic (4.47e-5)" "unprognostic (5.43e-2)" "unprognostic (7.46e-2)" "unprognostic (4.68e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (1.01e-2)" "unprognostic (2.32e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (5.23e-5)" "unprognostic (4.80e-2)" "unprognostic (3.98e-1)" "unprognostic (1.86e-2)" "unprognostic (3.51e-2)" 1.8 1.4 3.4 1.0 4.2 0.7 2.7 11.0 3.8 1.6 1.5 6.3 1.0 9.5 1.7 2.9 3.2 10.3 1.2 6.4 4.2 3.8 2.0 2.6 7.5 1.0 15.2 1.9 1.5 1.9 1.8 7.8 1.2 10.9 2.7 1.2 1.0 1.4 3.4 2.1 2.7 1.7 1.0 5.0 2.4 5.9 6.3 6.1 1.0 1.1 2.3 1.8 1.0 1.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.3 7.4 4.1 0.8 1.3 0.3 5.5 0.3 0.1 0.2 0.1 1.0 0.3 3.0 0.8 0.1 6.9 2.2 0.0 0.1 9.0 4.8 0.3 2.6 3.7 0.3 4.3 0.3 0.4 0.3 0.9 1.0 0.0 0.7 1.7 0.2 3.3 0.4 2.6 7.3 2.9 4.5 2.8 4.1 0.2 1.5 4.1 0.7 0.2 0.1 3.1 11.5 0.7 0.4 0.2 6.9 3.9 0.1 5.5 7.7 0.9 0.3 8.9 0.2 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 4.2 11.0 3.8 4.2 3.8 15.2 1.9 10.9 6.1 ZDHHC11B ENSG00000206077 "Zinc finger DHHC-type containing 11B" P0C7U3 5 710360-766952 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell line enhanced" "Detected in some" "HAP1: 5.0;RPMI-8226: 4.4;SCLC-21H: 6.5;THP-1: 7.0" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in single" "T-reg: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "HPA057886, HPA069008" Uncertain Approved "Lipid droplets" "Lipid droplets" "HPA057886: , HPA069008: " "unprognostic (2.81e-1)" "unprognostic (8.38e-3)" "unprognostic (3.79e-2)" "unprognostic (5.11e-3)" "unprognostic (7.18e-2)" "unprognostic (4.02e-3)" "unprognostic (1.19e-1)" "prognostic favourable (3.98e-4)" "unprognostic (4.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.45e-4)" "unprognostic (6.94e-2)" "unprognostic (1.43e-2)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (2.31e-1)" 0.3 1.8 2.9 0.0 3.7 0.0 0.6 11.7 5.3 0.0 1.1 3.8 0.5 0.4 2.8 3.4 0.5 3.8 3.9 2.9 0.4 0.6 5.3 0.0 2.8 0.8 2.4 1.5 3.7 0.1 0.6 1.9 1.0 0.4 3.3 4.8 5.9 0.0 2.5 3.3 3.8 0.8 0.7 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 1.9 0.8 2.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.2 1.0 0.3 0.0 2.4 5.0 0.2 0.0 3.0 2.3 0.0 1.9 0.9 0.0 1.5 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.2 0.0 0.0 4.4 0.1 1.5 6.5 1.9 0.1 0.0 0.6 0.1 7.0 0.1 0.0 2.5 0.0 0.0 2.4 0.8 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type containing 12" Q96GR4 9 128720869-128724127 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 77.4" "Cell line enhanced" "Detected in many" "MCF7: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" Nucleoplasm "Intermediate filaments" "HPA059339: " "unprognostic (2.05e-1)" "unprognostic (5.81e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-3)" "unprognostic (5.34e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-1)" "unprognostic (6.42e-2)" "unprognostic (9.97e-2)" "unprognostic (9.41e-2)" "unprognostic (1.09e-2)" "unprognostic (8.82e-3)" "unprognostic (2.18e-1)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" 7.3 10.9 3.9 15.3 4.5 21.8 11.2 2.5 6.5 7.5 21.2 6.8 19.3 16.2 5.9 8.3 27.2 6.9 21.5 9.2 3.5 3.1 20.6 23.6 14.2 28.0 3.8 3.8 5.0 40.5 4.3 5.0 24.7 4.8 11.1 8.4 7.7 26.3 13.3 7.5 16.8 33.0 5.4 5.8 14.9 18.7 9.2 2.7 23.6 10.3 16.4 24.4 10.1 11.7 22.2 50.6 77.4 28.7 17.4 26.1 18.8 14.1 38.8 1.6 8.4 5.1 3.5 16.4 9.2 8.2 10.0 6.7 31.8 16.4 9.9 8.6 6.8 37.5 3.5 18.1 1.0 18.2 9.3 5.2 29.5 13.9 10.3 8.7 24.1 5.6 12.6 8.2 3.1 7.4 5.2 25.2 1.9 54.5 11.9 17.4 7.2 32.1 5.4 5.8 28.4 7.6 13.3 11.6 8.4 12.4 17.2 4.8 26.5 9.3 7.4 0.0 10.5 7.1 12.2 16.3 28.8 4.4 16.8 10.0 11.0 39.2 26.5 77.4 23.5 24.7 20.3 20.3 21.8 22.5 21.0 22.2 22.7 20.6 56.8 17.4 28.7 50.6 26.1 18.8 3.9 4.5 2.5 6.5 3.5 3.1 3.8 3.8 4.8 2.7 ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type containing 13" Q8IUH4 11 19117099-19176422 "Enzymes, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Enhanced Vesicles Vesicles "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" 4.7 5.2 6.3 9.3 8.0 6.8 7.3 13.2 9.7 8.8 13.2 5.8 7.1 8.7 6.4 5.6 36.4 10.5 6.9 7.7 6.2 7.1 10.8 2.3 4.7 6.9 5.4 5.2 5.8 14.0 10.9 20.1 9.4 9.4 7.1 14.7 6.4 11.2 5.9 2.1 14.9 12.3 4.9 4.7 6.3 14.4 11.2 4.8 15.0 7.7 18.2 27.5 15.3 14.5 6.3 4.3 23.4 5.8 4.3 7.5 3.5 15.8 7.5 7.2 6.1 2.6 3.0 6.9 7.6 7.0 8.5 9.9 4.5 3.8 8.1 5.3 6.3 24.2 10.3 5.0 9.4 10.0 9.0 4.2 4.8 3.6 6.0 5.7 7.3 3.4 5.9 3.6 5.0 53.8 4.0 4.1 8.8 5.1 7.3 4.7 6.0 7.0 8.2 10.0 1.9 8.8 10.5 12.6 9.2 9.1 11.1 4.1 5.2 6.7 15.4 7.6 5.4 11.6 6.1 3.5 10.7 7.5 9.1 5.9 13.2 7.4 3.5 23.4 6.8 5.8 6.1 6.3 5.3 7.5 4.3 4.2 5.1 6.5 4.4 4.3 4.6 4.2 6.8 3.5 6.3 8.0 13.2 9.7 6.2 7.1 5.4 5.2 9.4 4.8 ZDHHC14 "FLJ20984, NEW1CP" ENSG00000175048 "Zinc finger DHHC-type containing 14" Q8IZN3 6 157381133-157678146 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 4.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063754 Approved Approved Nucleoli,Mitochondria Nucleoli Mitochondria "HPA063754: " "unprognostic (1.66e-2)" "unprognostic (1.27e-2)" "unprognostic (1.58e-2)" "unprognostic (3.98e-2)" "unprognostic (1.59e-1)" "unprognostic (6.78e-3)" "unprognostic (1.84e-1)" "unprognostic (6.02e-2)" "unprognostic (2.87e-2)" "unprognostic (1.63e-1)" "prognostic favourable (6.93e-4)" "unprognostic (3.94e-2)" "unprognostic (5.01e-3)" "unprognostic (1.89e-1)" "unprognostic (7.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.63e-1)" 6.4 3.9 9.0 4.4 10.8 4.8 3.6 15.6 16.2 7.4 5.3 22.1 2.9 6.2 22.6 2.6 4.2 4.8 5.3 11.1 10.6 8.8 6.9 8.7 6.4 4.8 15.8 7.1 3.3 5.7 12.7 3.7 5.1 15.3 7.9 4.0 9.1 4.6 3.8 4.7 3.3 8.6 13.7 22.0 6.4 8.1 6.3 11.8 0.7 3.8 1.5 5.7 5.3 5.0 1.5 4.2 0.0 0.1 0.4 0.9 0.4 1.7 1.8 0.5 2.5 1.4 1.0 5.8 2.7 2.5 1.9 1.7 2.2 1.2 4.2 0.9 2.1 0.8 1.4 1.4 1.7 32.7 2.1 8.2 0.6 1.0 1.9 1.1 1.8 0.7 1.5 2.0 0.8 2.9 6.6 3.1 1.1 1.1 0.7 2.7 1.0 2.1 0.1 0.3 2.5 3.9 0.7 4.2 1.2 3.1 2.0 2.3 0.3 1.3 4.0 2.9 2.1 5.6 3.4 0.7 0.8 0.6 1.0 2.9 3.1 0.0 0.1 0.0 0.5 0.0 0.9 1.5 0.4 0.4 0.0 0.8 0.0 0.3 0.0 0.4 0.0 4.2 0.0 0.4 9.0 10.8 15.6 16.2 10.6 8.8 15.8 7.1 15.3 11.8 ZDHHC15 "DHHC15, FLJ31812, MRX91" ENSG00000102383 "Zinc finger DHHC-type containing 15" Q96MV8 X 75368427-75523502 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 5.6;K-562: 3.5;LHCN-M2: 3.9;MOLT-4: 4.1;NTERA-2: 3.7;RH-30: 5.7;RPTEC TERT1: 3.1;SH-SY5Y: 4.7" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003618 Uncertain Approved "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "HPA003618: AB_2217686" "unprognostic (8.28e-2)" "unprognostic (1.73e-1)" "unprognostic (8.05e-2)" "unprognostic (1.62e-5)" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (4.00e-4)" "unprognostic (1.96e-2)" "unprognostic (3.19e-1)" "unprognostic (8.70e-2)" "unprognostic (3.77e-3)" "unprognostic (1.40e-1)" "unprognostic (4.78e-13)" "unprognostic (2.60e-3)" "unprognostic (1.17e-2)" "unprognostic (1.09e-1)" "unprognostic (9.67e-4)" 3.0 5.4 4.9 1.5 6.8 1.1 5.3 6.2 9.9 5.8 3.4 3.9 2.4 1.3 6.5 3.7 3.2 4.5 3.3 5.4 5.9 8.7 5.3 1.2 4.1 1.6 4.8 5.3 8.5 4.7 5.0 8.7 0.7 7.0 4.0 2.3 5.4 12.7 6.9 1.6 2.8 1.8 5.2 6.4 2.9 2.1 2.6 3.1 2.0 6.6 2.1 1.5 2.6 3.1 0.3 0.4 0.7 0.2 0.5 1.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 3.9 0.0 4.1 0.1 3.7 0.0 0.0 5.7 0.0 3.1 0.0 1.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.5 1.0 0.0 0.7 2.8 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.1 0.0 0.1 0.3 0.6 0.0 0.0 0.2 1.6 1.1 0.7 0.5 0.1 0.4 0.0 0.3 4.9 6.8 6.2 9.6 5.9 8.7 4.8 5.3 7.0 3.1 ZDHHC16 APH2 ENSG00000171307 "Zinc finger DHHC-type containing 16" Q969W1 10 97446131-97457370 "Enzymes, Predicted membrane proteins" "Apoptosis, DNA damage" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039893, HPA040214" Uncertain Supported "Nucleoplasm,Nuclear membrane,Cytosol" Nucleoplasm "Nuclear membrane, Cytosol" "HPA039893: AB_10794757, HPA040214: AB_2676886" "unprognostic (4.44e-2)" "unprognostic (3.14e-2)" "unprognostic (3.34e-1)" "unprognostic (1.20e-2)" "unprognostic (8.75e-2)" "unprognostic (8.35e-3)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (5.49e-2)" "unprognostic (1.57e-1)" "unprognostic (2.31e-1)" "unprognostic (6.34e-2)" "unprognostic (1.93e-3)" "unprognostic (1.34e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-1)" 12.0 13.7 15.9 10.8 17.3 6.4 17.9 17.6 24.6 17.1 17.9 15.6 18.1 15.1 15.5 21.2 17.6 11.5 14.4 18.1 13.2 11.0 23.3 37.4 20.8 11.1 10.9 13.0 15.1 22.5 21.8 15.4 30.7 10.5 16.0 18.9 18.1 28.5 14.1 20.7 14.0 15.7 17.6 8.5 13.2 19.4 16.4 10.8 14.7 19.6 15.4 16.1 15.1 20.0 9.3 14.2 9.4 10.4 13.0 12.0 5.8 21.4 25.2 16.8 20.7 26.9 18.5 17.6 23.6 31.5 27.3 26.1 19.6 19.2 18.9 27.3 34.5 25.3 21.1 33.4 24.4 18.7 24.5 12.0 17.7 18.6 21.6 14.3 17.7 20.6 22.1 31.9 23.0 28.0 9.6 14.4 34.5 20.5 21.6 19.6 13.7 21.9 14.8 17.1 17.4 23.1 9.9 8.2 11.7 14.4 14.9 12.8 19.7 14.0 17.1 17.2 16.0 11.1 27.6 13.8 22.3 11.6 19.9 22.2 9.0 0.3 9.8 9.4 7.0 10.4 8.0 8.2 12.0 11.1 14.2 9.3 9.9 9.8 0.5 13.0 10.4 10.9 9.4 5.8 15.9 17.3 17.6 24.6 13.2 11.0 10.9 13.0 10.5 10.8 ZDHHC17 "HIP14, HYPH, KIAA0946" ENSG00000186908 "Zinc finger DHHC-type containing 17" Q8IUH5 12 76763588-76853696 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 16.3" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016807, HPA058674" Approved Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA016807: AB_1858999, HPA058674: " "unprognostic (1.06e-1)" "unprognostic (2.26e-2)" "unprognostic (2.63e-2)" "unprognostic (3.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-3)" "unprognostic (3.09e-1)" "unprognostic (8.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.56e-3)" "unprognostic (5.42e-2)" "prognostic unfavourable (7.11e-5)" "unprognostic (1.77e-2)" "unprognostic (2.69e-1)" "unprognostic (2.98e-1)" "unprognostic (1.71e-2)" 7.9 7.8 10.0 5.8 14.0 11.3 8.8 18.1 18.1 8.0 5.9 9.2 3.8 3.6 12.0 6.8 6.4 7.0 5.5 6.4 8.7 6.5 9.1 13.1 5.4 7.1 11.3 10.7 11.5 5.2 9.5 10.3 8.7 13.2 7.9 5.4 5.9 5.7 7.3 5.4 5.9 6.4 8.0 10.0 7.1 6.1 6.4 11.6 7.5 6.2 4.1 5.7 5.6 6.3 3.8 16.3 5.8 2.2 1.7 3.6 1.4 5.7 7.1 22.2 11.3 13.4 14.2 10.9 11.7 9.7 7.8 6.9 5.6 4.2 8.0 7.1 11.3 5.5 8.8 7.3 12.2 6.7 9.3 11.6 8.7 8.5 9.0 11.6 10.4 13.3 7.7 7.3 11.0 8.9 12.5 3.7 10.1 5.4 8.3 15.6 16.4 8.1 11.3 7.9 8.7 9.0 8.9 8.7 15.1 12.9 4.7 7.5 10.5 11.7 12.3 10.7 8.1 6.5 6.6 6.0 5.8 8.7 4.0 5.5 11.0 5.7 2.1 5.2 3.6 2.2 2.9 2.6 2.9 2.7 2.6 3.8 3.1 2.6 5.8 1.7 2.1 16.3 1.2 1.4 10.0 14.0 18.1 13.8 8.7 6.5 11.3 10.7 13.2 11.6 ZDHHC18 DKFZp667O2416 ENSG00000204160 "Zinc finger DHHC-type containing 18" Q9NUE0 1 26826710-26857602 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 86.2" "Cell line enhanced" "Detected in all" "HDLM-2: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 20 "granulocytes: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040234 Approved Approved Microtubules Microtubules "HPA040234: AB_10805709" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "prognostic unfavourable (5.15e-4)" "unprognostic (1.01e-1)" "prognostic unfavourable (7.42e-7)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" "unprognostic (2.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.91e-1)" "prognostic unfavourable (1.36e-10)" "unprognostic (3.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 20.5 8.2 13.3 22.7 18.9 86.2 39.0 21.4 18.4 10.2 13.0 11.9 7.5 11.7 12.4 6.4 19.3 9.9 13.5 9.8 13.5 20.0 7.8 14.5 16.2 23.5 16.3 12.8 9.6 10.8 7.1 10.5 20.3 15.2 10.7 13.9 11.2 14.1 9.8 8.7 16.3 12.2 16.6 10.4 27.1 10.8 7.0 9.5 11.7 14.6 10.1 23.3 16.5 24.7 0.2 0.4 27.0 0.6 0.5 1.3 0.2 18.1 8.1 13.2 9.1 11.0 7.7 13.0 10.9 13.0 19.3 14.4 7.4 11.7 8.4 7.0 14.5 12.8 14.0 6.5 16.6 53.1 11.9 8.1 5.9 10.3 9.5 7.2 7.1 6.6 8.9 17.7 11.8 10.7 8.4 17.5 7.6 8.8 13.6 5.8 12.6 7.8 11.3 11.4 8.9 8.1 4.6 6.1 7.4 7.3 5.6 8.0 5.0 7.1 9.1 13.3 10.3 21.8 12.5 20.9 14.9 7.2 7.6 13.1 9.0 0.0 0.2 5.1 0.9 0.6 0.7 0.2 0.6 0.6 0.4 0.1 0.4 0.4 27.0 0.5 0.4 0.2 1.3 0.2 13.3 18.9 21.4 18.4 13.5 20.0 16.3 12.8 15.2 9.5 ZDHHC2 "DHHC2, ZNF372" ENSG00000104219 "Zinc finger DHHC-type containing 2" Q9UIJ5 8 17156029-17224799 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023331 Uncertain "HPA023331: " "unprognostic (8.92e-2)" "unprognostic (4.23e-1)" "unprognostic (1.80e-2)" "unprognostic (2.53e-1)" "unprognostic (6.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "prognostic favourable (3.24e-4)" "unprognostic (5.00e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-2)" "unprognostic (5.10e-2)" 10.1 22.5 14.8 9.4 14.5 24.4 14.8 22.8 12.2 12.9 13.4 17.5 17.4 9.3 7.0 10.5 5.3 12.8 6.4 10.1 13.0 14.0 24.2 7.5 12.7 10.3 13.6 10.9 13.0 27.0 19.2 20.2 6.1 14.7 12.0 10.3 21.2 15.9 13.7 15.9 3.4 9.1 8.8 25.9 11.2 14.1 14.2 14.5 13.8 32.3 10.4 10.2 17.3 8.7 5.3 4.6 4.9 2.7 4.4 7.0 1.5 1.0 5.4 10.5 2.2 9.2 16.5 6.1 18.0 21.9 10.2 12.2 1.7 15.0 10.9 7.1 15.6 0.7 14.1 8.9 19.0 7.1 7.1 9.8 7.8 2.1 9.2 10.3 1.2 6.9 1.4 12.8 11.7 16.8 1.1 29.3 12.3 0.2 7.6 6.2 6.6 8.3 7.6 10.5 4.0 18.6 11.5 5.6 3.7 7.7 0.0 1.7 0.4 4.7 13.9 5.2 16.0 11.5 17.9 5.8 21.9 12.8 14.4 9.5 2.3 2.6 2.6 4.9 4.1 2.7 7.0 5.3 5.1 4.9 2.2 4.6 4.7 5.0 1.8 4.4 1.6 4.6 2.6 1.5 14.8 14.5 22.8 12.2 13.0 14.0 13.6 10.9 14.7 14.5 ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type containing 20" Q5W0Z9 13 21372573-21459370 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Approved "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "HPA014483: AB_1859000, HPA014702: AB_1859001" "unprognostic (1.31e-1)" "unprognostic (2.16e-3)" "unprognostic (7.31e-3)" "unprognostic (8.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "prognostic unfavourable (6.55e-4)" "unprognostic (1.10e-1)" "prognostic unfavourable (1.01e-4)" "unprognostic (3.76e-2)" "unprognostic (7.65e-2)" "unprognostic (6.15e-2)" "unprognostic (1.13e-2)" 7.5 7.0 8.3 9.4 33.6 14.9 11.3 6.4 15.3 10.3 10.9 21.0 7.6 10.8 9.3 5.6 18.4 7.1 10.0 5.4 12.7 11.8 3.8 7.6 10.6 12.3 47.4 4.9 6.5 6.1 4.0 5.3 10.8 26.1 9.2 9.6 3.1 10.4 9.9 5.5 12.2 15.4 8.9 45.0 8.6 23.1 22.0 35.8 10.4 10.0 5.1 10.9 16.2 9.6 4.6 7.8 8.8 15.2 10.1 10.2 11.1 13.5 7.8 11.4 7.2 10.6 11.2 27.9 14.8 14.9 9.9 8.9 14.2 41.5 14.4 8.0 18.1 22.0 13.1 11.4 18.8 15.7 8.3 25.3 4.9 7.8 6.0 17.1 11.0 10.2 8.0 9.8 6.9 15.3 7.0 6.1 14.7 11.4 23.9 6.5 9.3 7.7 19.2 20.5 5.0 11.8 25.2 10.9 5.0 19.5 12.2 8.0 11.2 8.7 26.6 10.5 10.0 17.6 11.0 6.3 7.7 15.0 7.5 9.9 29.5 8.8 15.2 3.4 10.2 14.2 9.4 4.6 8.8 8.7 7.8 3.7 8.3 8.5 2.7 10.1 12.0 3.9 9.3 11.1 8.3 33.6 6.4 15.3 12.7 11.8 47.4 4.9 26.1 35.8 ZDHHC21 "DHHC21, DNZ1, HSPC097" ENSG00000175893 "Zinc finger DHHC-type containing 21" Q8IVQ6 9 14611071-14693471 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 22.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065254 Approved Approved "Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" "HPA065254: " "unprognostic (2.95e-2)" "unprognostic (1.45e-1)" "unprognostic (2.06e-2)" "unprognostic (2.01e-1)" "unprognostic (4.19e-2)" "unprognostic (2.58e-2)" "unprognostic (2.81e-2)" "unprognostic (1.13e-2)" "unprognostic (2.18e-2)" "unprognostic (8.37e-2)" "unprognostic (9.79e-3)" "unprognostic (3.97e-2)" "prognostic favourable (1.29e-4)" "unprognostic (1.21e-1)" "unprognostic (1.14e-1)" "unprognostic (8.87e-2)" "prognostic favourable (9.28e-6)" 6.5 10.8 15.9 7.9 16.8 4.2 11.6 29.0 22.6 7.8 8.5 9.3 3.8 12.2 9.8 11.7 14.4 7.5 6.7 9.0 13.8 10.4 9.4 4.8 9.2 11.1 9.4 16.5 10.0 8.4 11.5 22.2 7.8 14.8 10.0 9.9 6.6 8.3 7.4 7.7 15.7 12.6 7.7 9.9 9.5 7.9 7.3 9.7 4.7 11.3 9.9 10.7 7.7 11.3 5.2 1.4 0.5 0.8 2.8 1.7 0.6 5.3 2.7 5.4 3.5 0.9 1.0 4.2 6.8 2.1 2.4 2.8 1.3 2.5 5.3 1.7 4.8 3.5 3.7 2.2 3.5 10.6 2.9 22.5 6.0 2.6 2.9 3.9 7.5 1.8 5.2 2.8 1.8 14.2 1.8 0.6 4.3 2.9 0.9 3.8 3.8 5.2 0.0 2.6 2.6 7.6 5.9 3.3 8.9 3.1 3.9 2.1 4.9 6.5 10.1 1.8 2.7 1.7 6.2 2.2 4.1 0.0 3.7 0.2 1.8 0.5 0.4 0.1 1.2 0.8 1.3 5.2 1.2 1.1 0.2 3.5 0.8 1.2 0.0 2.8 0.6 1.4 1.7 0.6 15.9 16.8 29.0 22.6 13.8 10.4 9.4 16.5 14.8 9.7 ZDHHC22 C14orf59 ENSG00000177108 "Zinc finger DHHC-type containing 22" Q8N966 14 77131270-77142734 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 52.3" "Group enriched" "Detected in some" 4 "AF22: 5.2;NTERA-2: 5.5;RH-30: 9.2;SCLC-21H: 10.2" "Cancer enriched" "Detected in single" 40 "glioma: 7.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049471, HPA072213" Enhanced "Plasma membrane" "Plasma membrane" "HPA049471: , HPA072213: " "unprognostic (1.02e-1)" "unprognostic (3.42e-1)" "unprognostic (1.22e-4)" "unprognostic (1.66e-1)" "unprognostic (8.86e-2)" "unprognostic (2.68e-1)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "unprognostic (6.94e-4)" "unprognostic (3.05e-1)" "unprognostic (6.30e-2)" "unprognostic (1.16e-1)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" "unprognostic (4.79e-1)" 1.1 1.5 11.2 1.1 12.6 1.1 1.1 8.4 52.3 1.1 1.2 6.7 0.0 1.1 1.1 1.4 1.3 1.2 1.1 1.2 14.5 18.4 1.1 1.1 1.1 1.1 10.7 19.5 1.1 1.1 1.1 3.1 1.1 9.2 1.1 1.3 0.5 1.1 1.1 1.3 1.1 1.1 1.2 3.6 1.1 1.3 1.4 5.1 0.0 1.3 0.0 1.1 1.4 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 5.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 5.5 0.7 0.0 9.2 0.0 0.0 0.0 10.2 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 11.2 12.6 8.4 29.5 14.5 18.4 10.7 19.5 9.2 5.1 ZDHHC23 MGC42530 ENSG00000184307 "Zinc finger DHHC-type containing 23" Q8IYP9 3 113947901-113965401 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 25.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 2.7;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016808 Uncertain Approved Nucleoplasm Nucleoplasm "HPA016808: AB_1859002" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (4.48e-3)" "prognostic unfavourable (2.85e-4)" "unprognostic (1.49e-1)" "unprognostic (3.98e-3)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (3.19e-1)" "unprognostic (6.63e-2)" "unprognostic (1.86e-1)" "unprognostic (2.78e-2)" "prognostic favourable (1.48e-7)" "unprognostic (2.58e-2)" "unprognostic (1.83e-1)" "prognostic unfavourable (5.90e-4)" "unprognostic (3.29e-3)" 1.0 0.8 6.3 2.1 5.9 0.4 1.9 2.7 10.4 1.4 7.7 0.9 2.2 6.0 1.5 1.6 1.7 2.1 1.8 1.3 8.9 1.9 4.7 3.2 2.4 2.7 0.9 4.7 1.1 4.4 8.2 3.5 0.4 1.4 1.8 9.9 1.2 4.9 1.4 1.2 2.9 5.4 0.7 0.9 1.9 5.0 25.8 0.6 0.8 5.5 0.9 2.8 1.7 1.5 2.7 1.1 0.5 0.0 0.0 0.5 0.1 13.3 3.4 0.4 7.9 1.2 0.2 11.6 5.3 1.6 1.0 1.6 5.5 9.0 6.1 4.7 3.0 8.8 10.1 1.4 1.7 3.6 4.6 5.7 4.9 3.4 0.4 6.3 5.3 0.2 1.7 0.2 0.7 0.9 0.0 3.6 0.1 7.7 5.2 0.4 2.4 3.8 0.9 4.6 5.1 5.6 6.6 13.9 3.5 4.1 13.7 2.6 8.2 2.1 0.2 3.8 7.7 0.8 2.3 4.1 5.3 9.9 3.3 4.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.5 0.1 0.0 1.7 0.1 0.0 0.5 0.0 0.0 1.1 0.1 0.1 6.3 5.9 2.7 10.4 8.9 1.9 0.9 4.7 1.4 0.6 ZDHHC24 ENSG00000174165 "Zinc finger DHHC-type containing 24" Q6UX98 11 66520637-66546238 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016619 Approved Approved Vesicles,Cytosol "Vesicles, Cytosol" "HPA016619: AB_2288672" "unprognostic (2.77e-1)" "unprognostic (2.51e-1)" "unprognostic (2.52e-1)" "unprognostic (1.55e-3)" "prognostic unfavourable (3.28e-4)" "unprognostic (8.76e-2)" "unprognostic (7.74e-3)" "unprognostic (7.11e-2)" "unprognostic (6.20e-2)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (1.48e-1)" "unprognostic (8.10e-2)" "unprognostic (6.99e-3)" "unprognostic (3.10e-1)" "unprognostic (4.88e-1)" "unprognostic (1.35e-1)" 11.7 17.4 10.5 10.3 12.8 14.1 12.3 5.7 15.5 7.7 8.3 13.8 10.8 9.1 9.4 17.0 12.2 9.0 11.3 9.9 10.7 11.8 17.3 13.4 11.1 20.4 12.8 10.3 6.5 19.4 22.6 9.6 13.7 9.3 11.4 7.7 10.0 12.4 13.1 7.9 13.2 9.4 7.1 10.0 16.0 12.4 9.9 10.5 11.7 17.7 7.9 13.4 10.0 7.8 5.8 17.2 2.4 5.5 6.6 7.2 4.6 4.8 7.8 2.6 6.7 6.4 5.3 6.5 4.1 3.5 3.3 2.3 6.8 7.9 1.4 11.2 3.5 12.0 1.9 3.6 2.3 7.0 4.9 3.0 3.8 4.2 6.0 3.0 7.5 6.3 6.5 2.7 3.9 5.5 4.3 4.4 4.1 10.6 5.8 8.5 5.1 6.7 7.5 5.4 9.1 4.0 3.9 3.6 5.7 6.6 6.9 11.3 9.5 2.5 8.5 7.6 2.4 8.8 3.0 6.5 2.0 2.0 6.6 1.4 8.2 2.4 5.5 1.0 6.2 4.8 5.7 5.4 5.0 7.2 6.3 5.8 3.0 5.4 2.4 6.6 4.4 17.2 5.1 4.6 10.5 12.8 5.7 15.5 10.7 11.8 12.8 10.3 9.3 10.5 ZDHHC3 "DHHC3, GODZ, ZNF373" ENSG00000163812 "Zinc finger DHHC-type containing 3" Q9NYG2 3 44915257-44976185 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012465, HPA016616" Approved Approved "Golgi apparatus" "Golgi apparatus" "CAB012465: , HPA016616: AB_1859004" "unprognostic (2.80e-1)" "unprognostic (6.07e-2)" "prognostic favourable (3.43e-4)" "unprognostic (3.10e-2)" "unprognostic (2.47e-2)" "unprognostic (3.38e-1)" "prognostic unfavourable (1.37e-4)" "unprognostic (4.20e-2)" "unprognostic (1.04e-1)" "unprognostic (6.37e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "prognostic favourable (1.81e-8)" "unprognostic (2.64e-1)" "unprognostic (1.49e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-2)" 23.1 25.8 11.7 17.5 14.0 29.5 39.8 12.5 20.8 17.2 27.9 13.7 17.8 18.4 19.2 17.9 29.1 13.0 22.7 34.6 11.2 9.1 21.7 19.0 20.2 16.1 12.1 7.7 16.5 15.0 16.9 8.8 19.5 19.4 16.1 28.9 14.7 17.4 22.5 20.0 43.0 33.2 15.4 13.6 15.4 20.9 48.0 10.1 14.1 20.4 22.1 20.6 21.4 20.7 5.4 11.4 17.1 10.0 6.0 7.1 5.2 11.9 9.6 8.7 12.1 37.3 18.9 9.7 10.6 13.3 13.6 12.2 11.6 15.8 10.9 5.7 18.7 15.4 13.4 18.7 14.4 10.8 5.7 9.6 13.3 8.5 8.5 25.0 7.9 16.2 23.1 12.9 12.8 14.2 14.1 9.7 12.4 7.7 7.5 18.2 11.6 19.2 5.6 7.3 8.2 13.4 37.6 2.7 10.5 12.7 13.2 5.8 9.9 17.3 15.1 11.8 10.8 13.7 13.8 6.7 12.4 10.8 10.7 38.3 8.7 17.1 10.0 13.8 6.5 5.5 6.1 4.7 4.7 7.1 11.4 5.4 4.9 6.3 11.4 6.0 7.2 6.7 6.9 5.2 11.7 14.0 12.5 20.8 11.2 9.1 12.1 7.7 19.4 10.1 ZDHHC4 "FLJ10479, ZNF374" ENSG00000136247 "Zinc finger DHHC-type containing 4" Q9NPG8 7 6577434-6589374 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032124, HPA064358" Approved Approved "Nuclear bodies" "Nuclear bodies" "HPA032124: AB_10610699, HPA064358: " "unprognostic (1.07e-1)" "prognostic unfavourable (9.35e-4)" "unprognostic (6.82e-2)" "unprognostic (8.36e-2)" "unprognostic (3.66e-1)" "prognostic unfavourable (3.95e-6)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (4.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "prognostic favourable (1.18e-7)" "unprognostic (8.75e-2)" "unprognostic (9.41e-2)" "unprognostic (1.42e-1)" "prognostic unfavourable (8.94e-4)" 17.7 24.3 20.7 13.5 22.0 11.4 23.6 8.2 29.9 20.7 24.9 22.5 18.2 14.0 21.6 26.9 16.1 25.5 18.8 21.9 17.3 19.7 25.7 34.5 17.0 19.7 19.8 17.7 22.7 46.5 27.2 18.7 14.1 20.4 20.0 16.3 28.0 29.8 22.4 34.9 9.5 16.3 22.7 17.1 13.6 23.5 27.0 12.3 18.1 30.5 17.4 16.5 23.3 13.7 17.6 50.6 20.9 14.9 11.9 15.4 12.6 21.8 13.9 5.2 31.0 28.5 21.5 23.8 12.3 3.1 15.2 18.8 17.3 31.4 13.0 19.6 22.8 20.1 18.2 12.2 15.8 7.7 10.6 14.4 16.6 18.5 25.4 17.1 15.8 22.5 18.1 11.8 0.0 13.5 29.4 19.4 20.9 22.9 9.2 16.7 27.2 12.2 12.6 26.5 19.3 12.0 17.3 12.6 32.1 16.4 6.0 21.5 20.7 22.5 9.0 17.9 26.0 17.1 17.9 28.7 22.9 30.0 10.7 21.4 25.0 20.9 11.7 18.0 11.5 14.9 12.5 17.6 11.6 12.7 13.2 16.1 15.4 14.7 1.3 11.9 10.8 50.6 10.3 12.6 20.7 22.0 8.2 29.9 17.3 19.7 19.8 17.7 20.4 12.3 ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type containing 5" Q9C0B5 11 57667747-57701187 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA014670: AB_2257442" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-3)" "unprognostic (1.74e-3)" "unprognostic (4.36e-2)" "unprognostic (9.78e-2)" "prognostic unfavourable (6.74e-5)" "unprognostic (1.76e-1)" "unprognostic (4.72e-3)" "unprognostic (2.16e-1)" "unprognostic (6.80e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-3)" 19.6 18.2 6.9 14.2 16.1 13.0 17.3 12.4 19.2 20.0 18.7 14.1 20.9 14.6 19.8 15.9 45.8 16.0 19.1 18.2 8.2 8.1 27.8 24.8 18.7 18.0 8.5 8.2 16.2 21.3 31.4 13.9 31.4 12.8 15.5 18.2 19.1 29.3 18.4 31.3 33.2 25.9 15.2 8.7 21.5 16.3 35.7 7.8 26.4 25.5 23.9 39.1 23.3 26.0 9.4 13.4 15.5 11.3 6.9 13.1 9.0 27.9 31.1 12.2 12.4 27.0 20.8 23.0 26.3 31.6 22.1 16.5 18.8 34.5 18.9 34.2 31.1 39.6 19.0 31.2 19.7 23.2 8.6 16.0 14.3 16.7 30.3 30.0 27.2 29.3 28.2 32.6 33.1 24.8 21.1 23.9 27.8 16.8 16.9 8.4 14.8 18.7 16.8 24.7 23.3 25.2 41.6 8.9 11.4 24.5 27.7 25.7 29.7 17.2 29.1 28.6 14.9 30.0 18.3 17.4 21.5 16.3 21.3 15.5 24.8 15.5 8.1 9.8 11.1 10.1 13.1 9.0 10.9 9.4 8.0 9.4 11.0 11.1 10.2 6.9 11.3 13.4 9.8 9.0 6.9 16.1 12.4 19.2 8.2 8.1 8.5 8.2 12.8 7.8 ZDHHC6 "FLJ21952, ZNF376" ENSG00000023041 "Zinc finger DHHC-type containing 6" Q9H6R6 10 112424428-112446917 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014357 Approved "HPA014357: AB_2304658" "unprognostic (1.21e-1)" "unprognostic (1.00e-1)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.80e-1)" "unprognostic (2.07e-1)" "unprognostic (3.29e-2)" "unprognostic (6.24e-2)" "unprognostic (5.21e-1)" "unprognostic (3.54e-2)" "unprognostic (1.56e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-2)" "unprognostic (9.30e-2)" "unprognostic (8.87e-2)" "unprognostic (7.64e-2)" "unprognostic (1.22e-2)" 17.6 17.7 14.4 21.6 17.2 13.9 17.7 17.5 19.1 16.6 21.3 15.4 25.6 32.2 21.6 25.7 21.1 16.5 17.1 15.1 15.4 13.2 41.7 21.3 17.6 20.3 20.1 15.2 24.5 19.0 15.6 17.6 19.3 19.8 18.6 22.6 18.2 21.4 23.5 13.8 14.8 43.8 16.7 15.5 22.3 18.8 10.7 15.0 20.2 20.5 12.9 21.6 16.7 17.9 16.8 16.4 20.2 17.2 15.5 23.0 15.0 20.3 15.9 16.6 20.6 16.2 12.3 11.8 20.0 19.1 15.8 19.0 15.1 36.5 11.3 9.2 12.1 24.4 13.8 12.8 18.5 26.5 16.9 11.7 18.3 18.7 10.5 26.6 20.6 9.3 8.6 17.3 20.5 19.8 12.6 19.0 17.1 17.1 14.8 29.9 9.7 13.1 12.4 21.1 10.5 18.7 11.3 6.2 8.7 10.3 16.5 18.8 9.2 19.6 14.1 18.3 11.5 12.2 18.8 10.7 12.3 15.0 16.2 47.2 11.8 9.3 17.2 20.2 15.5 15.8 20.1 16.8 17.9 19.5 16.4 13.3 15.2 17.1 11.4 15.5 12.4 13.6 23.0 15.0 14.4 17.2 17.5 19.1 15.4 13.2 20.1 15.2 19.8 15.0 ZDHHC7 "DHHC7, FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370" ENSG00000153786 "Zinc finger DHHC-type containing 7" Q9NXF8 16 84974181-85011535 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019215, HPA059642" Uncertain Supported "Nucleoplasm,Golgi apparatus" "Golgi apparatus" Nucleoplasm "HPA019215: , HPA059642: " "unprognostic (9.77e-2)" "unprognostic (2.12e-1)" "unprognostic (6.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (8.76e-2)" "prognostic unfavourable (4.20e-4)" "unprognostic (1.41e-2)" "unprognostic (5.78e-2)" "unprognostic (2.21e-2)" "unprognostic (7.79e-3)" "unprognostic (8.04e-2)" "prognostic favourable (1.12e-5)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.45e-1)" "unprognostic (5.42e-2)" 23.4 20.9 17.7 25.4 14.7 40.3 45.8 17.8 20.0 23.7 26.8 15.5 15.6 19.7 27.7 18.6 20.4 19.2 29.1 24.9 13.0 11.6 23.4 21.3 31.3 36.3 15.5 14.5 21.8 30.0 31.1 15.2 25.1 14.8 24.1 24.3 18.1 18.7 18.4 36.5 23.1 25.5 31.1 14.9 27.1 32.3 18.6 13.9 16.1 19.9 25.8 18.8 27.7 28.9 2.0 6.9 8.5 10.6 1.5 3.0 3.5 20.0 17.7 9.4 11.2 41.6 31.4 12.9 18.6 36.1 29.3 14.6 18.6 23.6 9.2 10.9 30.0 21.2 12.0 24.5 37.0 5.3 9.6 7.2 7.5 21.1 17.4 12.5 7.0 25.9 28.2 23.9 13.8 15.0 21.4 3.2 18.5 24.0 8.5 12.0 14.5 12.9 10.6 8.6 5.0 28.8 26.5 8.0 10.1 24.0 13.5 11.6 25.5 7.6 21.9 17.7 13.5 16.7 10.8 11.1 15.3 20.9 16.8 9.4 14.0 6.7 10.6 8.5 2.5 8.8 3.0 1.6 2.4 2.0 6.9 2.0 1.8 2.6 7.1 1.5 7.2 4.7 0.6 3.5 17.7 14.7 17.8 20.0 13.0 11.6 15.5 14.5 14.8 13.9 ZDHHC8 "KIAA1292, ZNF378" ENSG00000099904 "Zinc finger DHHC-type containing 8" Q9ULC8 22 20129456-20148007 "Enzymes, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003422 Uncertain Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA003422: AB_1080640" "unprognostic (1.00e-2)" "prognostic unfavourable (9.68e-4)" "unprognostic (3.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-1)" "unprognostic (8.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-3)" "unprognostic (9.34e-3)" "unprognostic (3.20e-1)" "prognostic unfavourable (4.04e-4)" "unprognostic (1.11e-1)" "unprognostic (1.02e-1)" "unprognostic (9.88e-2)" "unprognostic (9.57e-2)" 20.7 19.2 25.7 16.9 23.0 9.2 23.4 24.4 35.3 14.3 9.9 14.0 17.3 11.6 16.0 10.9 13.9 13.6 14.4 16.0 18.7 10.6 15.2 16.5 14.6 15.4 17.7 17.6 18.0 23.9 17.4 21.0 16.4 19.0 13.4 7.0 17.5 20.4 16.6 20.5 22.2 11.2 13.0 10.4 19.8 15.9 8.4 18.6 8.9 18.5 7.9 11.1 12.9 14.5 2.0 4.1 4.0 1.5 1.3 2.5 0.5 11.3 7.3 11.6 15.3 17.1 10.2 10.5 21.5 14.7 14.6 13.1 3.8 5.9 0.0 8.9 17.8 15.6 6.1 16.4 7.2 16.4 23.3 5.5 19.1 8.7 14.1 0.0 7.7 17.8 11.1 11.2 9.5 16.3 38.0 9.0 12.9 5.6 6.7 14.9 5.9 11.6 14.4 10.2 4.1 6.3 13.9 18.7 9.5 8.7 4.2 10.2 0.3 7.8 18.6 33.2 24.3 18.6 9.5 13.0 4.2 4.3 9.7 7.2 9.7 4.0 1.2 0.3 2.5 1.5 1.3 0.8 0.7 1.2 0.4 2.0 1.3 1.8 0.0 1.3 0.8 4.1 2.0 0.5 25.7 23.0 24.4 35.3 18.7 10.6 17.7 17.6 19.0 18.6 ZDHHC9 "CGI-89, CXorf11, ZDHHC10, ZNF379, ZNF380" ENSG00000188706 "Zinc finger DHHC-type containing 9" Q9Y397 X 129803288-129843909 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031814 Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" "Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA031814: AB_10610700" "prognostic unfavourable (9.77e-5)" "prognostic unfavourable (4.64e-5)" "unprognostic (2.83e-2)" "unprognostic (7.53e-3)" "unprognostic (2.68e-1)" "prognostic unfavourable (2.45e-4)" "unprognostic (4.01e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-1)" "unprognostic (3.49e-2)" "unprognostic (9.70e-3)" "unprognostic (4.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.17e-2)" "unprognostic (4.11e-2)" 18.2 7.3 16.7 6.7 24.7 3.2 14.2 7.8 33.9 14.1 14.7 78.3 5.1 21.1 8.4 8.4 9.8 7.9 10.4 7.4 24.1 15.2 25.4 27.0 15.6 3.0 24.9 13.9 8.0 17.4 19.6 7.1 11.5 28.4 13.4 17.3 3.8 13.2 8.3 7.4 19.7 22.2 10.4 32.7 2.4 12.8 2.8 25.3 1.2 9.6 5.7 4.3 10.8 9.4 4.6 7.8 2.6 6.8 3.4 7.6 3.3 15.2 8.0 11.5 23.2 39.9 31.4 9.4 15.1 17.3 7.2 9.1 12.6 19.9 0.5 25.8 16.0 10.3 13.0 15.1 10.5 0.8 8.1 3.0 8.4 16.6 15.8 2.0 5.5 34.1 24.7 11.8 17.6 13.6 3.3 6.1 11.7 13.3 2.9 3.8 6.2 13.9 2.7 7.4 9.0 10.5 8.5 9.1 7.7 4.3 22.3 7.0 9.5 3.4 11.1 7.4 2.5 17.3 12.1 5.7 4.1 1.8 13.3 8.4 3.7 0.0 3.3 2.6 4.8 2.9 6.1 4.6 5.8 4.7 3.7 2.7 7.6 4.3 0.0 3.4 6.8 7.8 2.5 3.3 16.7 24.7 7.8 33.9 24.1 15.2 24.9 13.9 28.4 25.3 ZFP91 "PZF, ZNF757" ENSG00000186660 "ZFP91 zinc finger protein" Q96JP5 11 58579111-58621042 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA024037, CAB025417" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB025417: , HPA024037: AB_1859051" "unprognostic (6.10e-2)" "unprognostic (5.01e-2)" "unprognostic (3.33e-3)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (2.33e-2)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (2.36e-2)" "prognostic unfavourable (3.74e-6)" "unprognostic (3.16e-1)" "unprognostic (1.75e-3)" "unprognostic (3.12e-2)" "unprognostic (2.61e-1)" "unprognostic (2.23e-1)" "unprognostic (2.00e-3)" 17.1 14.7 20.1 13.6 25.6 32.0 14.9 24.4 21.7 15.3 18.1 23.2 15.8 16.2 16.3 11.8 16.3 13.6 13.8 26.5 20.3 15.4 16.3 19.4 15.0 14.4 20.8 18.1 14.9 14.3 26.7 17.0 14.2 19.7 13.1 21.9 11.2 14.5 15.5 33.8 17.5 19.6 16.9 21.6 15.0 13.9 71.0 19.4 15.7 16.8 14.6 15.9 17.8 21.4 4.6 7.0 5.4 5.0 3.7 5.4 2.8 24.5 14.1 16.6 16.8 15.9 19.3 9.1 20.3 38.2 23.6 20.2 7.7 26.0 29.4 20.1 25.6 21.9 16.8 21.6 31.1 15.6 9.4 19.4 14.4 8.3 18.1 24.4 32.0 16.8 21.2 33.1 38.8 23.3 19.2 27.9 30.3 8.2 21.1 13.5 8.7 13.8 16.4 28.0 19.5 17.3 23.7 17.8 14.2 25.9 23.9 33.1 26.6 18.4 26.1 29.8 20.6 44.8 22.5 16.2 11.9 24.5 26.3 13.8 30.3 3.9 5.0 3.5 5.4 4.5 3.0 4.5 3.3 3.3 4.9 4.6 3.6 4.6 5.4 3.7 4.2 7.0 2.6 2.8 20.1 25.6 24.4 21.7 20.3 15.4 20.8 18.1 19.7 19.4 ZMPSTE24 "FACE-1, HGPS, PRO1, STE24, Ste24p" ENSG00000084073 "Zinc metallopeptidase STE24" O75844 1 40258107-40294184 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006988 Approved Approved "Golgi apparatus,Cytosol" 13000 Cytosol "Golgi apparatus" "HPA006988: AB_1080659" "unprognostic (6.32e-2)" "unprognostic (1.63e-2)" "unprognostic (3.75e-3)" "unprognostic (4.63e-2)" "unprognostic (4.16e-3)" "unprognostic (1.37e-1)" "prognostic unfavourable (5.73e-6)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.84e-3)" "unprognostic (4.78e-2)" "unprognostic (7.96e-2)" "unprognostic (5.06e-2)" "unprognostic (3.65e-2)" "unprognostic (2.65e-1)" "prognostic unfavourable (6.34e-4)" "unprognostic (2.71e-2)" 21.6 24.2 17.6 15.4 19.6 6.5 18.6 10.7 21.3 20.9 20.6 14.9 27.0 17.9 29.7 19.7 21.4 19.9 20.7 20.8 17.1 16.9 34.2 48.7 16.2 23.1 21.9 17.0 16.0 20.4 39.8 17.0 23.0 23.5 21.7 23.3 15.6 18.9 19.0 19.1 14.7 20.9 25.2 19.2 17.7 19.0 10.7 17.9 20.9 20.6 14.7 18.4 19.1 16.7 15.1 25.8 15.1 23.9 24.2 22.5 20.3 20.7 13.9 10.8 8.1 28.7 23.0 21.0 21.8 18.2 24.6 22.5 15.1 36.0 17.9 15.1 26.6 21.6 22.0 20.0 28.4 16.8 14.1 17.3 14.8 13.8 16.4 27.8 21.7 16.6 20.6 21.0 9.1 17.3 18.3 18.0 23.3 9.7 16.8 8.3 20.7 14.5 14.6 19.2 22.2 21.8 20.1 11.3 13.3 20.1 44.9 27.0 16.5 76.8 17.1 22.3 16.3 20.7 26.4 11.1 29.6 15.6 24.4 19.5 23.6 15.1 20.0 13.6 17.9 23.9 21.5 15.1 19.1 18.9 25.8 11.6 17.0 22.5 11.8 24.2 22.7 16.9 22.3 20.3 17.6 19.6 10.7 21.3 17.1 16.9 21.9 17.0 23.5 17.9 ZNRF1 "DKFZp434E229, FLJ14846, nin283" ENSG00000186187 "Zinc and ring finger 1" Q8ND25 16 74999030-75110994 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 80.1" "Cell line enhanced" "Detected in many" "HMC-1: 53.8;MOLT-4: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 4.5;T-reg: 5.2" "Group enriched" "Detected in many" 4 "granulocytes: 4.5;monocytes: 1.4;T-cells: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027470 Approved "HPA027470: AB_10603108" "unprognostic (2.78e-2)" "prognostic favourable (9.90e-4)" "unprognostic (4.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.34e-2)" "unprognostic (1.18e-2)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-2)" "unprognostic (5.38e-2)" "unprognostic (3.69e-1)" "unprognostic (2.28e-1)" "unprognostic (1.46e-1)" "unprognostic (4.89e-2)" "unprognostic (2.87e-1)" "unprognostic (2.10e-2)" "unprognostic (1.44e-2)" 10.0 9.5 13.4 8.1 13.7 5.2 16.6 6.3 16.5 13.2 12.5 8.1 6.7 8.3 10.7 9.1 28.2 10.0 11.3 9.1 11.6 14.6 5.6 12.8 12.8 8.7 9.1 9.4 10.1 6.1 12.2 6.2 9.7 7.8 9.1 10.8 7.2 7.5 7.5 58.6 14.5 11.2 10.1 8.8 2.8 11.8 21.6 4.9 80.1 21.4 16.9 13.3 14.0 15.5 0.2 0.8 4.5 1.4 0.0 5.2 0.3 3.1 4.6 8.0 8.2 8.6 6.7 27.7 3.8 5.4 5.3 5.2 7.4 9.9 0.8 3.0 8.3 7.6 3.9 5.3 4.2 7.7 2.2 16.5 1.5 13.6 6.8 7.9 53.8 6.0 4.4 5.5 4.5 8.6 7.9 2.6 4.1 30.2 38.5 29.1 11.1 5.0 17.1 3.0 5.0 7.5 9.0 10.7 11.5 6.1 8.1 2.2 21.5 7.5 5.8 3.7 6.4 6.5 2.3 15.4 15.6 9.1 4.8 8.8 3.7 4.5 1.4 0.9 0.2 1.1 1.3 0.2 1.5 0.2 0.8 0.0 0.0 0.2 1.2 0.0 1.1 0.0 5.2 0.3 13.4 13.7 6.3 16.5 11.6 14.6 9.1 9.4 7.8 4.9 ZNRF2 RNF202 ENSG00000180233 "Zinc and ring finger 2" Q8NHG8 7 30284307-30367692 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 5.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072244 Approved "HPA072244: " "unprognostic (9.44e-2)" "unprognostic (2.38e-2)" "unprognostic (8.64e-2)" "prognostic unfavourable (7.68e-4)" "unprognostic (4.46e-2)" "unprognostic (1.24e-1)" "unprognostic (3.06e-1)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (5.93e-2)" "prognostic favourable (2.29e-4)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "prognostic favourable (8.71e-4)" "unprognostic (8.67e-2)" 7.8 8.0 10.0 9.3 10.6 9.7 16.2 12.8 10.0 5.8 16.1 10.5 7.6 11.3 7.7 9.7 14.2 5.2 8.7 8.4 9.6 6.1 19.3 24.0 7.9 12.0 10.0 7.4 5.8 14.0 8.0 9.9 9.6 11.0 7.0 14.3 5.8 10.5 13.7 17.5 11.5 12.7 8.3 10.5 9.2 12.4 20.6 9.1 7.9 13.3 9.8 10.9 9.4 11.8 1.3 5.8 1.4 1.1 0.7 2.4 0.5 6.6 2.4 2.0 1.7 2.3 1.6 10.5 2.5 2.6 2.8 3.9 1.2 11.2 7.0 6.7 2.0 6.5 6.6 4.3 3.1 6.8 6.0 4.3 5.2 3.2 1.2 3.3 8.3 2.5 7.4 1.9 4.8 2.3 5.3 14.0 3.0 2.5 6.8 8.9 4.6 3.0 5.9 4.3 11.9 8.6 14.4 6.9 6.5 5.1 21.7 4.3 5.8 13.6 2.6 2.8 4.8 2.6 5.3 24.0 20.5 9.1 3.0 7.3 4.0 0.5 0.9 1.1 1.0 0.9 1.5 1.3 1.2 1.4 0.8 0.8 0.7 1.1 1.4 0.7 1.1 5.8 2.4 0.5 10.0 10.6 12.8 10.0 9.6 6.1 10.0 7.4 11.0 9.1 ZNRF3 "BK747E2.3, FLJ22057, KIAA1133, RNF203" ENSG00000183579 "Zinc and ring finger 3" Q9ULT6 22 28883592-29057487 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 28.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036702, HPA036703" Uncertain Uncertain "Golgi apparatus" "Golgi apparatus" "HPA036702: , HPA036703: AB_10672227" "unprognostic (1.07e-1)" "unprognostic (2.13e-3)" "unprognostic (7.48e-3)" "unprognostic (5.72e-2)" "unprognostic (6.81e-2)" "unprognostic (1.36e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-2)" "unprognostic (5.18e-2)" "unprognostic (3.94e-1)" "unprognostic (9.55e-5)" "unprognostic (6.49e-2)" "unprognostic (1.02e-1)" "unprognostic (3.70e-2)" "unprognostic (2.55e-2)" 4.6 11.8 16.8 2.5 14.7 1.0 4.5 12.2 18.1 7.8 5.7 7.7 21.8 5.1 8.3 22.2 5.9 8.1 3.8 4.3 22.0 5.0 13.6 7.5 8.7 1.2 6.1 17.7 10.0 5.4 16.3 4.2 8.0 8.1 12.0 5.9 4.9 12.1 13.4 5.6 7.6 4.7 7.8 8.9 2.2 6.4 6.7 10.5 0.0 6.9 1.9 1.5 5.7 4.9 0.2 0.4 1.5 1.0 2.0 0.5 0.1 3.6 8.7 8.1 2.3 1.5 1.8 15.5 2.2 1.1 1.8 1.7 13.1 2.0 0.0 3.5 1.1 6.2 5.6 3.5 2.2 4.8 5.7 1.4 1.5 28.6 1.3 4.3 1.5 1.8 3.3 2.8 2.8 1.5 3.1 2.1 2.5 3.5 0.1 2.2 3.0 3.5 4.3 5.3 3.3 7.5 5.4 13.5 5.0 4.0 3.9 2.3 2.6 1.9 1.4 6.8 5.8 5.3 3.6 2.8 3.8 5.1 2.9 2.4 3.5 1.0 0.2 1.3 0.2 1.0 0.4 0.1 0.2 0.1 0.4 0.2 0.1 0.5 1.5 2.0 0.2 0.3 0.1 0.1 16.8 14.7 12.2 18.1 22.0 5.0 6.1 17.7 8.1 10.5 ZRANB1 TRABID ENSG00000019995 "Zinc finger RANBP2-type containing 1" Q9UGI0 10 124942123-124988189 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029239, HPA029240, HPA029241" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA029239: AB_10599419, HPA029240: AB_10601450, HPA029241: AB_10602205" "unprognostic (2.06e-1)" "unprognostic (5.16e-2)" "unprognostic (6.96e-2)" "unprognostic (1.67e-1)" "unprognostic (1.40e-1)" "unprognostic (9.53e-3)" "unprognostic (4.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (4.20e-1)" "unprognostic (1.46e-1)" "unprognostic (1.22e-2)" "unprognostic (1.60e-1)" "unprognostic (2.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.47e-2)" 5.1 9.3 4.9 1.9 4.7 7.9 5.3 11.9 6.0 6.3 5.2 1.4 5.9 5.2 4.1 4.4 3.6 7.3 4.6 4.0 4.2 10.4 4.2 2.5 4.4 8.6 3.1 7.1 3.9 3.9 4.6 3.3 3.4 5.8 18.0 5.2 3.0 6.3 3.8 2.8 3.6 7.7 3.8 3.9 4.2 4.8 3.4 1.4 4.6 1.1 3.8 4.4 0.8 7.7 4.4 9.5 6.9 14.8 12.5 4.0 7.6 20.8 14.5 16.9 6.6 6.1 8.1 5.7 9.6 5.6 12.0 5.6 19.6 8.6 5.9 4.6 5.1 7.1 31.6 6.9 3.5 13.8 16.5 10.6 22.8 9.1 0.6 6.7 7.8 6.1 8.1 6.0 3.4 4.8 7.0 6.7 3.6 6.4 5.6 4.8 8.1 6.4 5.0 8.4 5.5 5.9 6.7 6.2 6.4 5.1 9.4 7.2 6.2 9.4 7.0 4.9 3.0 2.1 1.1 3.0 2.2 0.4 1.9 2.4 2.6 2.2 0.9 3.4 4.4 3.3 4.6 3.8 0.5 1.4 2.2 0.8