Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 109.8" "Group enriched" "Detected in some" 6 "HEL: 22.0;HSkMC: 23.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favourable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favourable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavourable (9.76e-4)" "unprognostic (2.30e-2)" 109.8 4.0 6.7 16.2 4.2 5.7 54.5 23.3 5.4 40.1 13.1 2.4 10.2 6.5 28.8 23.0 32.6 27.1 26.9 47.1 9.1 3.4 5.7 1.3 27.8 36.8 19.2 0.6 22.3 8.1 3.9 2.0 5.8 14.0 29.1 7.1 5.3 12.8 9.8 38.3 19.8 11.5 36.6 9.4 25.0 13.0 21.6 6.4 3.0 16.5 29.9 15.5 42.3 24.2 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 22.0 0.0 0.0 4.1 0.0 0.0 23.9 0.0 0.0 3.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.7 4.2 23.3 5.3 9.1 3.4 19.2 0.6 14.0 6.4 ACKR2 "CCBP2, CCR10, CCR9, CMKBR9, D6" ENSG00000144648 "Atypical chemokine receptor 2" O00590 3 42804752-42887974 "G-protein coupled receptors, Predicted membrane proteins" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "placenta: 96.2;salivary gland: 74.8" "Cell line enhanced" "Detected in some" "BEWO: 31.4;HEL: 10.0;SK-BR-3: 16.8;U-937: 6.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "eosinophil: 7.3;NK-cell: 2.2" "Group enriched" "Detected in many" 5 "granulocytes: 7.3;NK-cells: 2.2" "Group enriched" "Detected in many" 9 "amygdala: 2.3;basal ganglia: 7.0;cerebral cortex: 5.0;hippocampal formation: 2.6" "Low region specificity" "Detected in all" "HPA013819, HPA073493" Enhanced Supported Nucleoplasm,Vesicles,Cytosol "Vesicles, Cytosol" Nucleoplasm "HPA013819: AB_1846126, HPA073493: " "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.90e-2)" "unprognostic (8.15e-2)" "unprognostic (7.51e-2)" "unprognostic (1.54e-2)" "unprognostic (1.21e-3)" "unprognostic (1.74e-1)" "unprognostic (2.99e-1)" "unprognostic (6.20e-2)" "unprognostic (8.47e-2)" "unprognostic (8.45e-2)" "unprognostic (1.13e-4)" "unprognostic (5.13e-3)" "unprognostic (3.22e-1)" "unprognostic (5.58e-3)" "unprognostic (6.09e-2)" 10.4 0.9 0.4 0.7 0.5 0.4 5.3 0.2 0.4 2.9 1.8 0.1 0.6 0.7 2.0 5.2 2.5 2.4 1.2 1.0 0.5 0.4 1.1 14.5 1.5 1.0 0.5 0.2 0.9 0.7 0.3 0.6 96.2 0.2 1.1 2.0 0.3 74.8 0.4 2.1 2.5 1.0 3.2 0.7 1.1 0.9 1.5 0.1 0.4 3.8 2.3 2.0 3.2 4.1 0.8 0.4 7.3 0.6 2.2 0.4 0.3 0.1 0.0 0.1 0.2 1.4 0.1 31.4 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.1 10.0 0.2 1.7 0.0 0.1 1.1 0.3 0.3 0.0 0.0 0.0 1.3 0.2 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 4.4 0.1 0.1 0.7 16.8 0.0 1.6 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.0 6.4 0.1 0.7 0.2 7.3 0.4 0.5 0.1 0.2 0.1 0.2 0.4 0.8 0.3 0.3 1.0 2.2 0.6 0.3 0.1 0.3 0.4 0.5 0.2 0.4 0.5 0.4 0.5 0.2 0.2 0.1 ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582358 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HeLa: 22.8;MCF7: 16.8;RT4: 66.7;SiHa: 20.4;U-2197: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 6.1;T-cells: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "HPA032003: , HPA049718: " "unprognostic (1.65e-2)" "prognostic unfavourable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavourable (1.76e-6)" "prognostic unfavourable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavourable (2.93e-4)" 56.1 2.9 5.4 6.9 5.6 1.7 28.5 2.2 6.4 10.7 15.2 8.9 9.1 5.7 9.9 20.4 23.6 14.6 15.3 30.2 8.4 3.0 3.8 29.6 10.9 7.2 3.8 6.5 19.3 25.7 2.2 10.7 59.6 8.4 14.2 12.8 25.2 8.9 8.9 36.4 16.0 15.7 32.6 7.2 70.9 12.6 9.4 5.5 0.2 34.3 22.3 8.6 59.2 17.8 1.0 0.2 0.1 0.5 6.1 6.1 0.6 0.0 0.0 1.3 0.0 2.3 0.0 9.8 0.5 0.3 0.4 1.0 0.1 0.0 0.0 1.1 0.0 14.3 0.0 5.1 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.6 13.1 0.0 0.0 2.3 0.2 0.0 0.0 16.8 0.0 0.0 2.3 0.1 0.0 1.6 0.1 0.0 66.7 0.0 0.0 20.4 0.1 0.0 0.0 0.0 0.0 0.1 5.3 70.1 0.0 0.2 0.0 0.0 0.2 1.4 0.1 0.0 0.1 0.0 4.1 0.3 6.1 0.6 2.1 5.0 0.2 1.0 1.8 2.3 0.1 6.1 0.5 0.0 3.1 0.6 5.4 5.6 2.2 6.4 8.4 3.0 3.8 6.5 8.4 5.5 ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597237-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.6;salivary gland: 29.0" "Cell line enriched" "Detected in some" 6 "BJ hTERT+: 86.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "basophil: 1.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.8" "Group enriched" "Detected in some" 7 "cerebellum: 5.3;pons and medulla: 1.6" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria "Vesicles, Mitochondria" "HPA054926: " "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-2)" "unprognostic (8.27e-2)" "unprognostic (5.17e-2)" "unprognostic (4.55e-3)" "unprognostic (8.93e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (4.20e-3)" "unprognostic (1.03e-3)" "unprognostic (2.69e-3)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" 13.9 1.9 0.3 2.9 0.4 0.5 10.9 0.4 0.4 3.7 8.7 0.2 4.5 16.2 5.6 7.1 5.7 2.6 9.8 7.1 0.6 0.6 6.6 2.0 10.0 2.7 0.6 0.2 2.1 3.0 0.0 8.2 0.7 0.6 5.2 1.2 1.3 29.0 2.0 3.1 10.7 35.6 5.0 0.4 1.5 10.5 3.4 0.1 0.8 1.8 12.8 1.5 8.2 4.5 0.2 0.0 1.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 6.2 3.4 0.0 14.2 86.6 0.8 2.4 0.0 0.1 0.9 0.0 8.8 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.4 0.4 0.6 0.6 0.6 0.2 0.6 0.1 ADCYAP1R1 "PAC1, PAC1R, PACAPR" ENSG00000078549 "ADCYAP receptor type I" P41586 7 31052461-31111479 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.2;fallopian tube: 25.1" "Group enriched" "Detected in some" 6 "AF22: 5.4;NTERA-2: 7.2;SCLC-21H: 6.1;SH-SY5Y: 10.9" "Cancer enriched" "Detected in some" 11 "glioma: 45.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030739, HPA049877" Enhanced Enhanced Vesicles Vesicles "HPA030739: , HPA049877: " "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.16e-2)" "prognostic favourable (5.78e-4)" "unprognostic (2.17e-1)" "unprognostic (8.36e-2)" "unprognostic (4.93e-2)" "unprognostic (5.75e-2)" "unprognostic (3.50e-2)" "unprognostic (3.88e-1)" "unprognostic (1.58e-1)" "unprognostic (6.67e-3)" "unprognostic (6.43e-4)" "unprognostic (1.09e-3)" "unprognostic (9.55e-2)" "unprognostic (3.85e-2)" "unprognostic (2.75e-4)" 5.4 10.6 23.6 2.7 24.2 0.9 2.9 13.7 71.2 12.8 2.7 13.4 0.0 1.6 5.4 2.3 3.3 25.1 2.0 2.8 22.1 21.6 1.0 1.1 1.6 1.0 19.0 20.2 1.9 2.2 2.9 4.4 1.0 18.7 2.1 2.0 0.0 2.6 3.7 1.9 1.8 2.0 3.9 6.5 1.3 1.6 2.2 13.3 0.0 2.3 0.9 1.6 1.4 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 6.1 10.9 0.0 0.0 0.0 0.0 0.0 0.3 0.9 1.3 0.2 0.1 0.0 0.0 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 23.6 24.2 13.7 17.3 22.1 21.6 19.0 20.2 18.7 13.3 ADGRA1 "GPR123, KIAA1828" ENSG00000197177 "Adhesion G protein-coupled receptor A1" Q86SQ6 10 133070929-133131675 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 7.8;brain: 26.6" "Cell line enriched" "Detected in single" 18 "RH-30: 11.9" "Cancer enriched" "Detected in single" 13 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042773 Approved "HPA042773: AB_10794764" "unprognostic (8.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (1.09e-2)" "unprognostic (7.51e-3)" "unprognostic (2.48e-2)" "unprognostic (3.33e-1)" "unprognostic (1.66e-1)" 0.8 7.8 9.9 0.7 9.3 0.7 0.7 3.5 26.6 0.7 0.7 3.2 0.0 0.7 0.7 0.7 0.7 4.3 0.7 0.7 11.6 14.6 1.0 1.1 0.9 0.7 7.5 6.6 0.7 0.8 0.7 1.9 0.7 5.3 0.7 0.7 0.3 4.1 0.7 0.7 0.7 0.7 0.7 4.6 1.0 0.8 1.0 1.4 0.0 0.7 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 9.3 3.5 19.0 11.6 14.6 7.5 6.6 5.3 1.4 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 36.2;ASC TERT1: 24.3;BJ: 16.1;BJ hTERT+: 27.2;fHDF/TERT166: 27.8;HHSteC: 17.1;HSkMC: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "classical monocyte: 1.4" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain 140000 "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavourable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 14.6 2.5 3.0 13.8 3.2 0.7 15.4 4.9 5.7 38.0 11.3 2.9 21.8 3.8 29.2 17.5 12.4 21.8 28.4 9.1 3.2 2.3 5.7 2.7 8.1 7.3 3.3 3.1 30.1 3.0 0.9 5.6 25.7 3.8 32.9 4.1 30.5 4.8 32.8 3.0 6.7 6.5 40.2 2.0 5.9 6.8 7.1 1.2 1.7 6.2 10.1 6.0 25.9 18.3 0.0 0.5 0.4 1.4 0.1 0.1 0.4 0.1 0.8 0.1 1.7 36.2 24.3 0.2 16.1 27.2 1.7 5.0 0.1 0.0 0.0 2.7 27.8 0.3 1.3 0.0 0.6 0.6 0.7 0.0 0.7 0.0 17.1 0.0 0.0 16.9 0.1 1.3 0.2 8.0 0.0 0.2 0.4 0.4 0.0 3.0 1.3 0.2 2.5 1.6 0.1 0.0 0.0 0.1 7.6 0.4 0.1 2.2 0.0 6.4 7.5 2.9 4.0 4.2 1.2 2.4 0.1 0.0 0.3 8.4 3.1 0.0 1.4 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.4 3.0 3.2 4.9 5.7 3.2 2.3 3.3 3.1 3.8 1.2 ADGRA3 "FLJ38547, GPR125, PGR21" ENSG00000152990 "Adhesion G protein-coupled receptor A3" Q8IWK6 4 22345071-22516054 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 51.8" "Cell line enhanced" "Detected in many" "RH-30: 32.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 5 "NK-cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008904 Uncertain "Intracellular and membrane" 160000 "HPA008904: AB_1849258" "unprognostic (3.70e-1)" "unprognostic (9.01e-2)" "unprognostic (5.32e-3)" "unprognostic (8.27e-3)" "unprognostic (4.58e-2)" "unprognostic (1.55e-1)" "unprognostic (8.15e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (3.91e-2)" "unprognostic (8.77e-2)" "unprognostic (1.88e-1)" "unprognostic (1.78e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-3)" 5.3 6.9 15.5 3.0 14.7 1.2 7.6 5.7 11.6 8.2 11.8 12.8 5.9 5.0 10.9 7.1 3.8 15.6 5.4 7.4 17.8 8.6 7.5 51.8 3.5 2.4 13.1 8.5 6.6 14.6 9.7 5.5 6.4 14.2 8.9 12.3 6.7 5.7 10.6 11.8 3.1 4.8 10.0 12.8 1.8 6.4 4.5 11.8 3.2 17.9 4.1 1.8 4.6 3.6 0.0 0.3 0.0 0.0 2.9 0.6 0.0 8.2 6.2 16.0 13.3 13.0 5.9 14.4 10.1 11.1 6.8 3.7 7.0 16.5 1.3 5.2 4.8 9.2 10.0 14.4 9.8 0.0 7.1 0.7 4.8 15.5 4.3 7.1 0.0 5.5 18.0 4.4 7.7 10.2 7.4 0.2 11.3 3.6 6.3 0.2 17.6 6.3 29.7 32.8 2.0 8.2 8.5 12.0 13.8 4.2 0.3 7.1 4.4 6.2 0.2 10.3 7.4 4.6 9.4 1.2 0.0 0.0 5.6 5.1 7.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.9 0.0 0.3 0.0 0.0 15.5 14.7 5.7 11.6 17.8 8.6 13.1 8.5 14.2 11.8 ADGRB2 BAI2 ENSG00000121753 "Adhesion G protein-coupled receptor B2" O60241 1 31727117-31764893 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 52.0" "Cell line enhanced" "Detected in many" "HeLa: 20.5;SH-SY5Y: 15.0;T-47d: 17.3;U-2 OS: 16.9" "Cancer enhanced" "Detected in many" "glioma: 20.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052612, HPA054617" Enhanced Centrosome 49000 Centrosome "HPA052612: , HPA054617: " "prognostic favourable (6.46e-4)" "unprognostic (1.74e-1)" "unprognostic (7.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.90e-1)" "unprognostic (2.40e-1)" "unprognostic (8.17e-4)" "prognostic unfavourable (4.02e-5)" "unprognostic (2.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-3)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (1.75e-3)" "unprognostic (7.98e-2)" 2.2 5.4 15.9 1.3 26.8 1.1 1.4 7.9 52.0 2.4 1.4 7.3 0.0 5.2 2.4 1.2 1.6 2.2 2.1 2.8 18.9 8.0 1.4 0.9 1.3 1.3 7.4 16.5 1.8 1.4 1.3 2.7 3.8 8.4 2.4 1.1 1.3 1.4 3.1 1.1 1.5 5.0 2.4 2.9 1.8 1.8 3.2 6.3 1.5 3.2 0.0 1.1 2.0 0.5 0.4 0.0 0.0 0.0 0.0 0.9 0.3 0.5 4.4 4.1 11.9 1.2 0.7 2.0 2.8 4.5 2.7 4.9 0.2 1.3 0.0 2.8 1.2 0.4 1.8 0.2 0.4 3.1 1.8 0.0 20.5 0.0 0.1 0.0 1.5 0.7 0.3 3.8 0.0 0.4 0.4 0.1 3.0 0.4 7.8 0.1 5.1 1.3 11.9 0.4 0.4 0.0 5.6 3.1 15.0 6.4 0.4 0.5 17.3 0.0 0.1 2.1 16.9 0.3 0.7 0.0 0.0 0.4 6.6 0.0 5.0 0.0 0.0 0.0 0.9 0.0 0.6 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 15.9 26.8 7.9 37.6 18.9 8.0 7.4 16.5 8.4 6.3 ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 66.1" "Cell line enhanced" "Detected in some" "BJ: 5.0;fHDF/TERT166: 5.7;HeLa: 10.3;HHSteC: 6.6;HMC-1: 14.2;U-2 OS: 7.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 4.1;intermediate monocyte: 4.9;myeloid DC: 2.4;non-classical monocyte: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;monocytes: 4.9" "Region enhanced" "Detected in some" "basal ganglia: 5.3" "Low region specificity" "Detected in all" HPA042395 Uncertain Approved Nucleoplasm,Cytosol 600000 "Nucleoplasm, Cytosol" "HPA042395: AB_10796906" "unprognostic (3.21e-1)" "unprognostic (1.49e-4)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-3)" "unprognostic (1.28e-1)" "prognostic unfavourable (9.27e-4)" "unprognostic (2.55e-3)" "unprognostic (1.63e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-5)" "unprognostic (1.31e-3)" "unprognostic (4.58e-1)" "unprognostic (2.15e-2)" "unprognostic (1.77e-3)" 12.7 2.1 2.0 3.2 3.1 0.5 8.9 1.1 3.9 11.2 5.5 2.2 3.9 2.2 13.3 14.0 6.8 8.8 45.6 34.8 1.9 1.5 1.6 5.2 18.6 0.6 4.2 2.2 12.5 11.8 0.3 3.5 26.6 2.4 13.3 2.4 13.0 1.6 2.3 11.6 3.8 6.4 66.1 6.4 1.9 10.2 3.8 2.6 0.0 6.3 7.1 2.1 29.5 30.8 0.2 2.4 0.0 4.9 0.5 0.0 1.2 0.0 0.7 0.0 2.5 0.0 0.0 0.1 5.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.3 0.0 6.6 0.0 14.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.1 0.2 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.5 7.0 1.9 0.1 0.1 1.8 0.9 0.1 0.0 0.0 0.0 4.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.5 3.6 0.0 0.0 1.2 2.0 3.1 1.1 3.9 1.9 1.5 4.2 2.2 2.4 2.6 ADGRE1 "EMR1, TM7LN3" ENSG00000174837 "Adhesion G protein-coupled receptor E1" Q14246 19 6887566-6940459 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "blood: 64.1;lymphoid tissue: 50.0" "Cell line enhanced" "Detected in some" "A549: 5.8;BJ hTERT+: 7.8;HDLM-2: 19.0;HMC-1: 13.6;Karpas-707: 16.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 64.1" "Group enriched" "Detected in many" 17 "granulocytes: 64.1;monocytes: 20.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA052809 Uncertain 9100 "HPA052809: " "unprognostic (2.06e-2)" "unprognostic (3.45e-1)" "unprognostic (1.32e-1)" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (6.93e-5)" "unprognostic (6.77e-2)" "unprognostic (1.18e-1)" "unprognostic (5.75e-2)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-7)" "unprognostic (6.69e-2)" "unprognostic (3.33e-4)" "unprognostic (1.11e-2)" "unprognostic (1.35e-1)" 1.8 0.5 0.7 7.2 2.4 5.9 0.5 0.3 1.7 0.5 0.6 0.3 0.0 2.8 0.4 0.9 0.4 0.6 0.7 1.3 1.5 0.7 0.7 4.1 4.6 6.6 1.7 0.0 0.3 0.4 0.0 1.0 1.8 0.9 0.5 0.5 0.5 0.5 0.0 0.4 0.3 2.8 1.7 1.9 50.0 0.7 1.2 1.0 6.9 0.5 0.0 1.7 2.8 0.4 0.0 2.4 64.1 20.2 0.1 2.0 1.9 2.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 0.1 0.0 0.0 0.0 0.4 13.6 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.1 0.5 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.2 0.3 0.1 0.8 3.0 0.1 3.9 3.6 0.0 27.2 4.3 64.1 0.0 12.0 0.0 0.0 1.5 0.2 2.4 0.0 2.0 0.1 1.6 0.1 20.2 0.1 0.4 1.9 0.7 2.4 0.3 1.7 1.5 0.7 1.7 0.0 0.9 1.0 ADGRE2 "CD312, EMR2" ENSG00000127507 "Adhesion G protein-coupled receptor E2" Q9UHX3 19 14732393-14778541 "CD markers, Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 28.7;lymphoid tissue: 38.9" "Cell line enhanced" "Detected in some" "HEL: 10.1;HMC-1: 16.3;NB-4: 9.8;RPMI-8226: 7.2;U-937: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 19.6;eosinophil: 24.2;intermediate monocyte: 15.7;neutrophil: 19.1;non-classical monocyte: 28.7" "Group enriched" "Detected in many" 8 "granulocytes: 24.2;monocytes: 28.7" HPA055200 Uncertain Vesicles,Cytosol Vesicles Cytosol "HPA055200: " "unprognostic (2.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (9.10e-2)" "unprognostic (3.58e-2)" "unprognostic (2.77e-2)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.32e-1)" "unprognostic (2.70e-2)" "prognostic unfavourable (4.35e-6)" "unprognostic (1.46e-1)" "unprognostic (2.45e-3)" "unprognostic (2.50e-1)" "unprognostic (1.01e-1)" 6.3 3.1 1.7 22.9 1.9 7.2 4.4 1.0 1.3 14.9 8.1 2.5 0.9 2.4 12.0 1.0 1.9 2.3 3.3 7.3 2.0 1.8 3.4 4.3 15.6 37.4 2.2 0.0 5.3 3.5 0.7 1.6 10.9 2.4 3.8 2.5 3.2 2.4 3.9 3.5 3.0 3.0 2.0 3.1 38.9 2.0 2.2 1.4 2.8 3.4 5.2 2.8 7.5 2.1 0.1 3.1 24.2 28.7 1.2 0.0 1.8 0.2 1.0 0.1 0.2 0.1 0.3 1.1 0.8 1.1 0.0 0.0 0.2 0.2 0.2 0.1 0.6 1.7 0.3 0.1 0.0 0.2 0.2 10.1 3.2 0.2 0.5 3.7 16.3 0.8 1.4 3.6 0.6 0.1 2.3 0.4 1.2 0.5 1.3 9.8 0.4 0.2 0.1 1.4 7.2 0.0 0.3 0.1 0.2 2.1 1.7 0.4 0.3 4.7 0.3 0.3 0.2 0.2 0.1 0.2 0.1 0.2 1.0 12.9 0.5 19.6 4.4 24.2 0.0 15.7 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 19.1 1.2 28.7 0.6 0.0 1.8 1.7 1.9 1.0 1.3 2.0 1.8 2.2 0.0 2.4 1.4 ADGRE3 EMR3 ENSG00000131355 "Adhesion G protein-coupled receptor E3" Q9BY15 19 14619117-14690027 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "blood: 70.7;lung: 26.3" "Cell line enriched" "Detected in single" 38 "HMC-1: 31.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 36.3;eosinophil: 69.6;neutrophil: 70.7" "Lineage enriched" "Detected in many" 9 "granulocytes: 70.7" "Not detected" "Not detected" HPA015638 Uncertain "Secreted to blood" "HPA015638: AB_1848039" "unprognostic (2.11e-4)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (5.69e-2)" "unprognostic (5.63e-2)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (8.07e-2)" "unprognostic (9.61e-2)" "unprognostic (9.11e-4)" "unprognostic (4.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.13e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" 1.7 0.2 0.3 8.5 0.8 4.0 0.3 0.2 0.7 0.2 0.4 0.3 0.1 2.1 0.2 0.7 0.4 0.6 1.2 0.6 0.3 0.3 0.4 1.1 26.3 5.9 0.4 0.1 0.5 0.3 0.0 0.3 1.7 0.7 0.6 0.5 0.7 6.2 0.1 0.9 0.2 3.2 0.7 0.6 8.1 0.4 0.8 0.3 0.8 0.5 0.9 3.4 2.6 0.4 0.0 0.7 70.7 8.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.3 3.2 69.6 0.0 7.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 70.7 0.0 8.0 0.0 0.0 0.9 0.3 0.8 0.2 0.7 0.3 0.3 0.4 0.1 0.7 0.3 ADGRE5 "CD97, TM7LN1" ENSG00000123146 "Adhesion G protein-coupled receptor E5" P48960 19 14380501-14408725 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 95.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA013707 Enhanced Approved Cytosol "Secreted to blood" 10000000 930000 Cytosol "HPA013707: AB_1846345" "unprognostic (3.16e-1)" "unprognostic (1.80e-1)" "unprognostic (5.10e-2)" "unprognostic (2.30e-1)" "unprognostic (2.85e-2)" "unprognostic (7.24e-2)" "prognostic unfavourable (3.73e-5)" "unprognostic (7.51e-2)" "unprognostic (6.06e-3)" "unprognostic (3.14e-2)" "unprognostic (1.08e-3)" "unprognostic (2.37e-1)" "prognostic unfavourable (1.87e-6)" "unprognostic (2.08e-2)" "unprognostic (4.14e-2)" "unprognostic (2.44e-2)" "unprognostic (6.41e-2)" 17.7 8.9 2.5 23.0 4.0 55.3 14.3 1.1 5.2 21.7 15.9 12.9 0.5 12.9 56.9 18.5 11.6 19.1 27.1 16.4 3.0 2.4 10.7 15.5 30.3 41.1 6.3 3.2 10.7 16.2 2.4 3.3 18.2 5.9 11.3 9.0 6.9 17.0 3.6 12.5 6.0 22.2 36.2 4.2 56.9 15.0 6.9 4.9 24.3 8.6 3.7 22.5 34.7 12.4 3.9 13.3 95.3 43.2 22.8 25.8 23.3 30.6 21.8 0.2 20.9 9.3 15.2 3.3 21.2 34.3 15.3 16.8 6.2 31.1 3.5 21.5 27.3 7.3 5.6 10.3 6.9 19.1 6.4 6.9 32.2 2.7 11.4 14.8 32.1 6.6 0.3 15.5 5.3 1.5 9.0 27.5 16.6 6.9 0.9 19.8 0.6 27.1 2.0 9.2 16.0 5.1 2.7 0.2 0.7 12.1 17.4 15.1 4.5 13.7 3.7 5.2 8.6 21.6 34.9 0.0 0.1 0.2 18.6 26.5 19.4 42.0 18.6 95.3 25.8 36.7 17.3 3.9 13.1 17.8 13.3 2.6 9.4 12.8 82.7 22.8 43.2 6.4 9.0 23.3 2.5 4.0 1.1 5.2 3.0 2.4 6.3 3.2 5.9 4.9 ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997703-47042363 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 27.4" "Cell line enhanced" "Detected in some" "A-431: 10.4;CAPAN-2: 39.1;HaCaT: 8.7;PC-3: 12.7;RPTEC TERT1: 17.9;RT4: 44.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038438 Approved "Secreted - unknown location" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favourable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 6.5 6.1 0.0 3.7 0.1 1.3 4.2 15.7 0.8 10.0 0.0 0.0 0.0 27.4 0.1 5.4 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.6 0.0 7.5 0.2 0.0 3.2 1.9 0.1 0.1 5.5 2.1 0.1 0.1 1.5 1.3 0.0 0.0 11.3 5.6 12.3 16.2 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.1 0.0 0.7 0.0 8.7 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 17.9 44.8 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ADGRF2 "GPR111, hGPCR35, PGR20" ENSG00000164393 "Adhesion G protein-coupled receptor F2" Q8IZF7 6 47656436-47697797 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 6.0;lymphoid tissue: 5.0;skeletal muscle: 4.7;skin 1: 6.0;tongue: 7.7" "Cell line enhanced" "Detected in some" "HBEC3-KT: 1.4;U-87 MG: 3.3" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA035507 Uncertain "HPA035507: AB_10601809" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (3.74e-2)" "unprognostic (5.95e-1)" "unprognostic (1.59e-1)" "unprognostic (1.53e-1)" "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" "unprognostic (2.51e-4)" "unprognostic (3.05e-2)" "unprognostic (3.86e-2)" "unprognostic (1.20e-1)" "unprognostic (2.24e-1)" "unprognostic (7.99e-2)" 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.4 1.2 0.3 0.1 0.0 0.0 0.0 0.2 0.0 6.0 4.2 0.0 0.5 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.8 0.6 0.3 0.2 0.0 0.0 0.4 0.0 4.7 6.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 7.7 5.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1.2 0.0 0.0 0.0 0.0 0.3 0.0 ADGRF3 "GPR113, hGPCR37, PGR23" ENSG00000173567 "Adhesion G protein-coupled receptor F3" Q8IZF5 2 26308173-26346817 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "vagina: 7.6" "Cell line enhanced" "Detected in some" "MOLT-4: 3.9;U-937: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA044500 Uncertain "HPA044500: AB_10794290" "unprognostic (9.58e-3)" "unprognostic (2.13e-2)" "unprognostic (4.07e-1)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (6.68e-4)" "unprognostic (8.98e-3)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" "unprognostic (9.66e-4)" "unprognostic (2.29e-1)" "unprognostic (8.09e-2)" "unprognostic (3.53e-2)" "unprognostic (2.58e-1)" "unprognostic (4.08e-2)" "unprognostic (8.70e-5)" 0.4 0.5 0.4 1.1 0.9 1.4 0.5 2.1 1.2 1.0 1.2 0.1 0.1 2.0 0.8 0.1 0.8 0.5 0.5 1.3 3.3 0.3 3.4 0.7 2.6 1.8 0.3 0.1 0.8 3.2 0.0 0.8 0.7 1.5 0.6 0.4 0.1 2.7 2.6 0.4 0.8 0.7 0.1 1.5 1.4 0.8 2.8 0.7 2.0 0.9 0.1 0.5 0.7 7.6 1.3 0.0 2.0 0.8 0.5 1.5 0.0 0.5 0.2 0.4 1.4 0.1 0.3 2.1 0.2 0.2 0.0 0.3 0.7 0.0 2.4 1.6 0.2 0.9 0.0 0.0 0.0 0.5 0.5 1.0 1.6 0.2 0.0 0.8 1.0 0.3 0.0 0.1 0.0 0.6 0.1 1.0 0.1 0.1 3.9 1.1 2.7 0.0 2.3 2.2 1.0 0.2 3.1 1.9 0.9 0.0 1.0 0.0 0.1 0.2 0.4 0.1 0.5 0.9 0.3 1.8 1.4 2.7 0.1 3.5 0.4 0.0 0.0 2.0 1.1 0.8 0.8 1.3 0.5 0.6 0.0 0.3 0.7 1.5 0.1 0.5 0.3 0.0 1.5 0.0 0.4 0.9 2.1 1.2 3.3 0.3 0.3 0.1 1.5 0.7 ADGRF4 "FLJ38076, GPR115, PGR18" ENSG00000153294 "Adhesion G protein-coupled receptor F4" Q8IZF3 6 47685864-47722021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.8;placenta: 23.9;skin 1: 30.7;tongue: 17.8" "Cell line enhanced" "Detected in some" "A-431: 5.7;HaCaT: 8.7;HBEC3-KT: 13.9;hTCEpi: 21.6;RT4: 5.4;U-87 MG: 18.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007131, HPA007158" Enhanced Uncertain Mitochondria Mitochondria "HPA007131: AB_2667756, HPA007158: AB_1849254" "unprognostic (1.40e-2)" "unprognostic (7.06e-3)" "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (3.79e-2)" "unprognostic (3.77e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-1)" "unprognostic (3.47e-1)" "prognostic unfavourable (5.52e-4)" "unprognostic (2.86e-1)" "unprognostic (1.66e-8)" "unprognostic (1.62e-3)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" 0.0 0.5 0.0 0.1 0.1 0.0 1.9 0.3 0.0 7.0 1.0 0.1 0.0 0.0 1.0 0.0 15.8 0.9 0.5 0.3 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 23.9 0.2 1.9 1.2 0.0 1.8 0.0 0.4 30.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 17.8 14.0 2.3 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.8 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 8.7 0.0 13.9 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 21.6 0.2 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 41.6;RPTEC TERT1: 39.1;SK-BR-3: 53.9;SK-MEL-30: 55.6;TIME: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 48.1" "Lineage enriched" "Detected in many" 6 "T-cells: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" 22000 "HPA046065: " "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavourable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favourable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" 18.9 5.6 39.3 5.1 32.3 6.5 19.7 9.1 70.9 15.2 14.2 28.2 14.6 10.3 10.0 34.5 16.8 20.3 26.7 8.7 33.4 15.9 82.1 1.9 15.4 2.2 24.2 22.8 3.1 25.2 13.5 6.7 38.1 27.2 13.0 13.4 6.3 34.3 24.7 5.7 32.6 7.7 7.8 32.0 4.9 18.1 22.1 28.9 12.1 81.4 8.7 7.2 17.8 14.2 0.1 0.1 1.0 0.2 8.7 48.1 8.4 7.7 8.5 2.5 0.1 0.0 0.0 24.9 1.4 0.8 2.5 0.5 6.4 41.6 0.0 20.8 1.3 28.5 0.0 19.3 1.0 0.3 0.0 0.8 10.4 7.3 0.0 0.0 0.4 0.5 27.9 4.5 1.9 20.6 0.0 0.3 0.5 9.6 20.5 0.1 0.3 8.3 0.7 0.2 5.7 39.1 24.6 7.2 0.2 0.4 53.9 55.6 23.9 0.1 44.6 4.7 7.7 0.3 17.3 0.0 0.3 0.1 38.6 0.1 11.3 0.6 0.2 0.0 48.1 0.1 0.5 0.1 3.3 18.3 0.0 0.0 1.7 14.1 1.0 8.7 0.1 0.1 0.0 8.4 39.3 32.3 9.1 35.0 33.4 15.9 24.2 22.8 27.2 28.9 ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989309-19122637 "Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 202.4" "Cell line enhanced" "Detected in some" "A549: 6.1;BEWO: 7.7;HeLa: 6.4;NTERA-2: 6.7;SH-SY5Y: 7.0;U-2197: 15.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" 7900000 "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" 4.4 0.3 0.4 0.9 0.2 0.2 2.8 0.1 0.2 0.8 1.0 0.1 6.6 0.2 0.5 202.4 0.9 6.9 1.4 1.8 0.6 0.6 0.7 0.9 1.7 3.1 0.2 0.2 0.9 0.9 24.8 1.9 0.6 0.3 3.2 0.2 1.6 9.6 0.8 0.6 0.3 1.4 0.6 0.2 1.2 3.5 4.7 0.2 2.7 1.8 0.6 1.9 1.1 1.5 0.1 0.2 0.9 0.6 0.0 0.2 0.0 0.2 6.1 0.0 0.0 0.1 0.9 7.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 6.4 0.2 0.9 0.0 0.0 0.1 0.1 0.0 1.2 0.0 0.0 0.2 0.0 1.0 0.0 2.3 6.7 2.0 0.0 0.1 4.4 0.0 1.2 2.3 7.0 1.5 0.1 0.0 0.1 0.1 0.1 0.2 0.4 15.3 2.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.9 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.0 0.7 0.0 0.6 0.1 0.0 0.0 0.4 0.2 0.1 0.2 0.6 0.6 0.2 0.2 0.3 0.2 ADGRG3 "GPR97, Pb99, PGR26" ENSG00000182885 "Adhesion G protein-coupled receptor G3" Q86Y34 16 57668187-57689378 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 42.8;bone marrow: 62.7;lymphoid tissue: 26.4" "Group enriched" "Detected in some" 6 "NB-4: 8.5;SK-MEL-30: 4.7;U-937: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "eosinophil: 33.3;neutrophil: 42.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 42.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040469 Uncertain "HPA040469: AB_10794032" "unprognostic (4.41e-3)" "unprognostic (3.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" "unprognostic (8.84e-2)" "unprognostic (1.64e-2)" "unprognostic (1.50e-4)" "unprognostic (5.25e-3)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.67e-3)" "unprognostic (4.75e-2)" "unprognostic (3.77e-1)" "unprognostic (1.00e-1)" "unprognostic (2.90e-1)" 4.6 0.4 0.3 7.2 0.9 62.7 1.6 0.2 0.5 1.1 4.1 0.0 0.0 1.4 1.4 2.0 2.9 3.4 1.6 7.7 0.2 0.3 0.7 2.7 11.0 26.4 2.0 0.0 1.7 0.6 0.2 0.3 1.7 0.6 1.6 0.9 1.2 0.4 0.3 2.3 0.7 3.9 1.5 0.3 25.4 1.2 1.7 0.3 1.1 6.5 1.2 0.8 3.4 7.2 0.0 0.0 42.8 0.0 8.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 15.6 0.0 33.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.8 8.8 0.0 0.0 0.0 0.1 0.3 0.9 0.2 0.5 0.2 0.3 2.0 0.0 0.6 0.3 ADGRG4 "GPR112, PGR17, RP1-299I16" ENSG00000156920 "Adhesion G protein-coupled receptor G4" Q8IZF6 X 136300963-136416888 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 21 "intestine: 23.6" "Cell line enhanced" "Detected in single" "TIME: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035324 Uncertain "HPA035324: AB_10671512" "unprognostic (3.40e-3)" "unprognostic (7.68e-5)" "unprognostic (7.61e-2)" 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 12.9 0.0 0.0 7.1 0.7 1.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.0 23.6 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADGRG5 "GPR114, PGR27" ENSG00000159618 "Adhesion G protein-coupled receptor G5" Q8IZF4 16 57542421-57591681 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood: 37.7;lymphoid tissue: 25.6" "Cell line enriched" "Detected in some" 6 "HMC-1: 28.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 37.7" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in single" "thalamus: 0.4" "Low region specificity" "Detected in single" HPA007133 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" "Nuclear membrane, Vesicles" Nucleoplasm "HPA007133: AB_1849253" "unprognostic (6.11e-3)" "prognostic favourable (4.25e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (6.14e-2)" "unprognostic (1.14e-2)" "unprognostic (6.43e-2)" "unprognostic (1.42e-2)" "unprognostic (8.09e-4)" "unprognostic (3.80e-3)" "unprognostic (3.02e-3)" "unprognostic (1.91e-1)" "unprognostic (4.37e-3)" "unprognostic (7.69e-3)" "unprognostic (4.52e-1)" "unprognostic (1.62e-3)" "unprognostic (6.32e-3)" 0.7 0.6 2.4 20.2 2.7 1.4 0.8 0.6 2.1 0.6 2.1 2.5 0.0 4.3 0.5 0.2 1.7 0.8 0.8 0.5 1.6 1.1 0.5 0.6 2.9 12.1 2.6 0.9 0.5 0.4 0.2 0.8 0.0 2.9 1.2 1.7 0.5 4.6 0.8 0.4 0.7 7.5 0.3 3.5 12.8 0.5 1.2 3.5 3.4 1.1 0.2 25.6 2.8 0.9 4.0 21.9 37.7 0.0 8.8 11.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 2.4 2.6 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 37.7 11.1 0.0 5.6 4.0 1.6 6.4 0.7 2.8 0.4 4.0 0.1 8.8 0.0 21.9 0.0 2.3 2.4 2.7 0.6 2.1 1.6 1.1 2.6 0.9 2.9 3.5 ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "liver: 51.9;placenta: 104.9" "Cell line enhanced" "Detected in many" "A549: 25.2;Hep G2: 23.5;hTERT-HME1: 23.9;HUVEC TERT2: 46.1;MCF7: 43.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 13 "myeloid DC: 3.5" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017346 Approved 70000000 "HPA017346: AB_1849260" "unprognostic (1.04e-2)" "unprognostic (2.72e-2)" "unprognostic (7.37e-2)" "unprognostic (3.00e-2)" "unprognostic (8.64e-4)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" "prognostic unfavourable (8.78e-4)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "prognostic unfavourable (2.78e-5)" "unprognostic (4.46e-1)" "unprognostic (6.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.97e-2)" "unprognostic (4.59e-2)" 5.6 1.4 1.1 4.1 1.0 0.0 6.1 0.5 1.1 4.1 14.0 1.0 2.7 8.9 2.2 2.8 9.1 2.6 8.8 4.4 1.4 1.1 5.3 51.9 12.0 2.6 1.9 0.8 1.4 3.1 0.3 0.7 104.9 1.3 7.2 3.3 3.3 6.3 3.6 1.5 7.8 17.5 5.0 2.3 6.1 6.6 1.5 0.9 2.2 2.1 3.9 4.7 11.3 9.2 0.0 3.5 0.0 0.2 0.0 0.1 0.0 4.7 25.2 0.5 2.6 0.1 0.0 0.0 6.5 1.2 5.0 3.1 20.1 14.6 0.0 5.9 3.7 11.8 0.7 6.3 8.3 0.0 1.9 1.0 4.3 23.5 4.9 4.0 0.0 0.0 10.2 0.1 23.9 46.1 0.1 0.0 2.0 43.2 0.0 0.0 0.2 5.7 0.0 2.2 4.9 2.6 10.7 0.0 0.0 1.9 8.9 4.1 4.8 0.0 1.5 0.0 2.2 2.2 3.2 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 1.0 0.5 1.1 1.4 1.1 1.9 0.8 1.3 0.9 ADGRL1 "CIRL1, KIAA0821, LEC2, LPHN1" ENSG00000072071 "Adhesion G protein-coupled receptor L1" O94910 19 14147743-14206187 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.9" "Cell line enhanced" "Detected in many" "AN3-CA: 31.2;HMC-1: 22.6;SCLC-21H: 24.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 4.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037974 Uncertain 63000 "HPA037974: AB_10675623" "unprognostic (5.52e-2)" "unprognostic (3.89e-1)" "unprognostic (1.04e-1)" "unprognostic (5.52e-3)" "unprognostic (6.29e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" "unprognostic (5.39e-2)" "unprognostic (2.73e-1)" "unprognostic (5.68e-2)" "prognostic favourable (1.14e-4)" "unprognostic (2.09e-1)" "prognostic favourable (4.45e-4)" "unprognostic (7.65e-3)" "unprognostic (1.32e-1)" "unprognostic (3.06e-2)" "unprognostic (2.18e-1)" 10.5 4.6 12.1 3.5 18.0 1.8 3.9 27.0 30.9 7.7 6.4 12.7 4.3 6.1 9.0 4.1 6.5 10.8 4.1 5.5 12.7 9.3 3.4 0.5 5.4 2.6 8.7 9.0 4.0 5.8 12.8 9.1 3.7 11.8 5.4 3.7 9.4 9.8 8.1 1.6 9.1 5.4 8.1 8.1 4.4 5.0 5.5 6.9 2.8 9.2 2.0 1.8 4.6 3.4 0.4 1.7 1.3 1.3 4.6 1.3 0.6 9.8 3.8 8.8 31.2 2.3 0.7 3.1 0.7 1.0 1.0 0.6 3.3 3.4 0.8 10.5 1.1 0.6 10.5 2.9 0.3 1.4 8.9 1.8 1.6 0.5 5.3 0.5 22.6 1.9 2.7 0.3 0.5 0.8 8.6 0.9 0.1 16.6 0.8 0.9 13.0 7.5 4.8 1.1 11.0 1.7 3.1 24.2 6.1 1.8 12.5 4.3 12.3 4.6 1.2 8.2 12.6 2.2 2.8 2.5 2.0 13.5 2.4 11.5 3.0 0.0 1.3 0.5 1.3 1.1 0.9 0.4 0.7 0.4 0.5 0.2 1.0 0.6 1.3 4.6 1.1 1.7 0.7 0.6 12.1 18.0 27.0 27.6 12.7 9.3 8.7 9.0 11.8 6.9 ADGRL2 "KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306160-81992436 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 62.8;hTEC/SVTERT24-B: 31.2;NTERA-2: 26.3;SH-SY5Y: 42.1;U-2197: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane,Cell Junctions" 280000 "Plasma membrane, Cell Junctions" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavourable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavourable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavourable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" 8.9 10.5 21.1 3.6 20.9 0.0 8.8 1.5 45.8 7.5 7.0 1.4 1.2 2.7 6.1 8.6 12.0 12.0 11.5 17.6 12.2 6.6 10.9 18.7 32.7 3.5 3.5 22.8 18.8 4.9 20.3 11.8 24.4 6.2 15.6 5.4 9.4 19.1 10.1 2.0 6.3 6.1 6.0 3.2 10.0 7.6 2.0 3.3 0.6 22.4 15.0 5.0 6.5 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 2.3 62.8 0.0 7.8 8.9 0.8 1.5 3.5 0.6 0.7 0.0 0.0 0.0 17.2 8.0 2.5 5.0 6.6 0.5 0.1 10.2 0.0 1.8 4.4 2.9 0.0 0.1 7.6 0.4 31.2 3.1 10.3 0.0 0.0 0.8 0.0 0.0 0.0 26.3 1.8 0.0 8.6 0.0 14.3 0.9 3.1 42.1 0.0 1.7 0.0 0.1 18.5 6.7 6.4 7.3 28.7 2.2 0.0 0.0 0.0 3.6 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 20.9 1.5 45.8 12.2 6.6 3.5 22.8 6.2 3.3 ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61201258-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.5;parathyroid gland: 23.1" "Group enriched" "Detected in some" 4 "AF22: 29.6;EFO-21: 7.7" "Cancer enriched" "Detected in some" 8 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" 4.9 7.6 19.7 1.6 19.0 0.4 2.7 11.3 30.5 7.3 4.8 5.0 0.4 3.3 4.9 2.6 1.6 3.3 2.3 3.2 13.1 12.3 2.4 0.9 3.4 0.8 11.8 11.9 1.8 0.7 23.1 0.9 4.9 9.8 2.0 5.0 0.4 0.8 5.6 0.8 2.6 4.4 3.9 8.5 0.8 3.9 4.8 6.1 0.0 0.9 0.6 0.6 2.2 2.9 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.7 0.0 0.0 4.1 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.3 0.0 0.0 0.7 0.0 2.8 0.1 0.1 0.0 3.2 0.1 0.0 4.5 0.2 0.0 0.0 0.0 0.0 2.2 0.0 0.1 3.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 19.7 19.0 11.3 23.3 13.1 12.3 11.8 11.9 9.8 6.1 ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79006718 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 98.9" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 63.2;TIME: 77.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported 1800000 "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavourable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" 98.9 4.7 3.6 5.6 5.7 0.0 43.8 3.2 6.1 14.6 7.8 1.5 6.6 2.8 12.9 7.1 12.4 6.8 12.3 12.3 4.3 3.7 11.3 8.8 16.2 8.5 5.4 1.4 9.3 3.0 5.7 7.8 12.8 6.2 12.2 3.6 5.9 4.8 5.7 16.1 5.3 4.8 16.0 4.7 34.8 4.9 6.8 4.3 1.1 13.9 8.0 3.9 16.0 25.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 1.6 5.2 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 3.8 0.0 10.9 0.0 63.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.1 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 5.7 3.2 6.1 4.3 3.7 5.4 1.4 6.2 4.3 ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 95.3;pituitary gland: 35.4" "Cell line enhanced" "Detected in many" "AF22: 12.4;HAP1: 18.4;K-562: 7.4;NTERA-2: 9.6;SCLC-21H: 9.0;U-266/70: 10.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067503 Approved Approved "Lipid droplets" "Lipid droplets" "HPA067503: " "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" 0.5 95.3 21.9 0.6 19.8 0.8 2.2 13.9 14.7 0.7 1.0 3.1 1.2 0.7 0.6 0.9 1.0 0.6 6.3 0.6 26.5 1.5 10.6 19.4 5.5 0.5 1.1 7.0 0.6 1.3 1.1 35.4 2.4 4.9 1.1 1.0 4.9 0.7 2.4 0.6 1.5 0.7 0.6 0.4 0.7 1.0 1.1 5.3 0.0 4.2 0.0 0.7 5.4 0.4 4.1 2.2 8.4 1.7 1.7 3.4 0.4 0.4 1.6 12.4 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 1.3 0.1 0.2 0.3 0.0 0.1 18.4 0.1 0.0 0.7 3.4 3.1 1.5 1.1 0.0 0.2 0.1 0.0 3.8 0.0 0.1 0.0 7.4 2.0 0.0 1.5 0.1 0.1 9.6 3.3 0.0 0.3 1.6 0.0 0.4 9.0 2.2 2.7 1.8 0.1 4.7 0.0 0.6 0.3 1.5 0.4 0.8 10.8 3.0 0.4 0.6 0.1 0.0 4.9 1.7 4.8 2.0 1.3 3.2 2.5 2.2 2.6 0.9 4.1 3.4 1.8 8.4 1.7 1.0 2.2 2.7 0.4 21.9 19.8 13.9 14.7 26.5 1.5 1.1 7.0 4.9 5.3 ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.7" "Cell line enhanced" "Detected in some" "CACO-2: 19.3;MCF7: 11.6;RH-30: 31.9;RPTEC TERT1: 15.5;SK-BR-3: 17.3;U-138 MG: 10.4" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" "Plasma membrane" "HPA044383: " "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" 4.5 1.0 19.7 2.6 21.7 0.8 6.1 9.7 38.7 1.1 1.6 27.4 0.0 2.0 2.0 1.6 1.6 2.0 1.8 13.8 19.8 12.1 4.2 1.0 2.8 1.4 22.8 13.4 0.8 15.5 15.5 0.9 8.9 25.0 1.2 1.6 1.8 8.9 1.3 2.0 1.9 1.8 1.3 20.7 7.4 1.6 16.3 15.9 0.0 3.2 0.0 1.4 3.4 0.3 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 1.4 0.3 0.1 0.1 0.8 0.1 0.9 1.4 0.3 0.2 19.3 0.3 0.0 4.4 3.5 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 3.0 11.6 0.0 0.0 5.0 0.0 0.0 31.9 1.0 15.5 0.0 0.3 0.3 2.1 17.3 0.2 1.0 0.4 0.0 10.4 5.3 0.0 5.6 0.0 0.0 0.0 5.2 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 19.7 21.7 9.7 25.7 19.8 12.1 22.8 13.4 25.0 15.9 ADORA2A "ADORA2, RDC8" ENSG00000128271 "Adenosine A2a receptor" P29274 22 24417879-24442360 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "blood: 22.8;bone marrow: 28.1;brain: 43.9;lymphoid tissue: 59.0" "Cell line enhanced" "Detected in many" "Daudi: 15.0;Karpas-707: 20.7;RPMI-8226: 14.6;SK-BR-3: 29.7;U-266/70: 20.8;U-266/84: 27.1;U-698: 21.2" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "basal ganglia: 43.9" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in some" 10 "basal ganglia: 357.5" "Region enriched" "Detected in single" 95 "basal ganglia: 166.0" "CAB001943, HPA065566, HPA075997" Enhanced Supported "CAB001943: , HPA065566: , HPA075997: " "unprognostic (7.30e-2)" "unprognostic (2.42e-2)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (1.88e-3)" "unprognostic (9.85e-2)" "unprognostic (3.63e-1)" "unprognostic (2.88e-2)" "unprognostic (4.57e-3)" "unprognostic (2.15e-3)" "unprognostic (1.87e-3)" "unprognostic (6.81e-4)" "unprognostic (1.50e-1)" "unprognostic (9.78e-3)" "unprognostic (1.30e-1)" "unprognostic (7.10e-3)" 1.0 2.4 1.9 10.4 43.9 28.1 1.5 3.4 3.8 0.8 2.0 1.7 0.3 5.4 1.4 1.4 1.0 0.9 2.4 3.5 2.4 1.8 3.5 4.3 5.1 14.8 2.6 1.6 1.2 0.8 0.0 2.1 1.4 2.3 1.6 0.8 3.3 2.7 1.5 1.2 0.9 2.6 0.7 1.3 7.5 2.8 2.0 5.7 59.0 1.3 0.9 8.6 3.8 1.3 17.7 1.1 13.7 9.0 2.2 22.8 11.2 0.2 0.3 0.4 0.1 0.2 0.1 0.4 0.2 9.3 0.5 0.9 1.7 0.1 15.0 1.0 0.2 0.3 0.9 0.0 0.0 1.8 2.6 0.2 0.0 2.1 0.1 0.3 7.5 0.1 0.0 2.8 0.0 3.3 0.1 20.7 0.0 0.2 5.2 1.6 0.6 0.0 0.1 0.7 14.6 0.0 0.1 1.5 8.7 0.4 29.7 0.1 0.3 1.4 0.2 0.9 1.4 0.2 0.1 20.8 27.1 21.2 4.7 5.1 0.1 3.0 0.8 4.8 8.6 2.6 20.1 9.6 16.1 16.9 1.1 17.7 22.8 18.3 13.7 2.2 9.0 1.1 21.4 11.2 1.9 43.9 3.4 3.8 2.4 1.8 2.6 1.6 2.3 5.7 ADORA2B ENSG00000170425 "Adenosine A2b receptor" P29275 17 15944917-15975746 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 56.7;hTERT-HME1: 21.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.8;myeloid DC: 8.4" "Group enriched" "Detected in many" 86 "dendritic cells: 8.4;granulocytes: 12.8;monocytes: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073747 Uncertain Cytosol Cytosol "HPA073747: " "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (4.68e-1)" "unprognostic (7.88e-3)" "unprognostic (2.64e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "unprognostic (1.38e-1)" "unprognostic (1.66e-9)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.84e-1)" 1.5 1.5 7.6 4.5 9.1 1.6 1.8 7.3 8.7 2.9 15.3 2.4 0.0 0.8 1.7 1.5 11.1 2.2 3.8 1.2 6.6 3.0 0.6 0.7 4.1 1.0 1.9 5.4 0.6 2.8 0.4 1.9 9.0 5.2 1.7 12.8 10.5 1.9 0.7 0.7 10.4 1.6 2.8 3.9 0.7 2.6 0.7 2.6 0.1 0.6 4.4 4.5 6.8 5.6 0.0 8.4 12.8 4.5 0.0 0.0 1.5 11.2 6.2 0.2 0.2 2.0 3.9 0.2 2.1 9.7 6.3 7.9 2.9 11.8 1.5 2.7 1.9 17.7 2.7 16.2 8.5 3.2 6.2 10.9 2.0 4.3 7.9 0.0 56.7 2.3 6.9 9.0 21.2 3.2 0.5 0.0 6.2 2.9 0.7 2.2 0.6 8.8 0.0 0.1 0.0 6.5 3.0 0.3 0.4 4.8 1.2 2.9 0.0 1.7 2.6 2.3 6.0 6.3 10.1 0.9 0.0 0.0 9.0 0.0 3.1 12.8 4.0 2.6 0.0 4.5 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.4 0.0 2.3 0.1 0.0 1.5 7.6 9.1 7.3 8.7 6.6 3.0 1.9 5.4 5.2 2.6 ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867273 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 45.1" "Group enriched" "Detected in some" 5 "ASC diff: 1.3;HAP1: 1.8;NTERA-2: 2.4;U-2 OS: 1.5" "Cancer enhanced" "Detected in some" "liver cancer: 0.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029678, HPA029679" Approved Supported "HPA029678: AB_10602108, HPA029679: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" 14.5 0.7 7.1 1.1 3.9 0.3 3.4 6.2 4.9 0.9 1.5 5.9 4.9 1.0 1.8 2.0 0.9 0.6 0.5 10.1 11.6 2.0 0.8 45.1 3.9 1.4 4.7 4.7 1.0 0.5 0.3 0.6 0.3 3.8 10.2 0.7 0.6 4.6 11.2 0.6 0.9 1.3 2.4 1.9 7.0 1.2 0.5 4.2 0.0 0.6 0.1 0.6 0.6 0.7 0.3 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.3 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 7.1 3.9 6.2 4.9 11.6 2.0 4.7 4.7 3.8 4.2 ADRA1B ENSG00000170214 "Adrenoceptor alpha 1B" P35368 5 159865080-159972544 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.6;liver: 20.3;lymphoid tissue: 17.4" "Cell line enhanced" "Detected in some" "EFO-21: 13.0;HaCaT: 6.6;TIME: 11.0;U-2 OS: 9.2;U-251 MG: 7.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074416 Supported "Plasma membrane" "Plasma membrane" "HPA074416: " "unprognostic (4.93e-3)" "unprognostic (2.94e-2)" "unprognostic (1.79e-1)" "prognostic unfavourable (6.00e-5)" "prognostic unfavourable (6.98e-4)" "unprognostic (4.08e-3)" "unprognostic (1.67e-3)" "unprognostic (1.68e-1)" "unprognostic (6.12e-2)" "prognostic favourable (2.67e-4)" "unprognostic (2.28e-1)" "unprognostic (1.37e-1)" "prognostic unfavourable (1.40e-6)" "unprognostic (5.24e-4)" "unprognostic (2.54e-1)" "prognostic favourable (3.19e-5)" "unprognostic (1.59e-2)" 5.3 2.9 5.3 0.9 9.0 0.4 2.3 1.3 21.6 0.9 1.2 0.7 0.8 1.2 1.5 3.6 1.1 3.6 1.3 3.3 6.2 5.8 7.4 20.3 4.7 2.3 1.2 13.9 6.2 0.8 1.0 0.8 1.1 5.2 1.6 1.1 0.9 1.0 1.9 1.6 1.3 1.7 1.2 0.9 17.4 0.9 0.8 0.5 0.0 2.0 0.0 1.1 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.7 0.3 0.0 2.4 0.9 0.1 0.5 0.2 0.6 0.3 0.0 4.2 0.0 13.0 3.8 6.6 0.0 0.5 0.3 0.0 0.3 0.0 1.6 0.0 5.0 0.0 0.0 2.8 0.0 0.0 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.6 0.0 0.7 0.0 4.5 0.0 0.4 0.0 0.0 0.3 0.4 0.1 0.0 11.0 0.1 9.2 0.0 7.0 0.0 0.0 0.0 3.3 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 9.0 1.3 21.6 6.2 5.8 1.2 13.9 5.2 0.5 ADRA1D "ADRA1, ADRA1A, ADRA1R" ENSG00000171873 "Adrenoceptor alpha 1D" P25100 20 4220631-4249074 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.7" "Cell line enhanced" "Detected in some" "A549: 2.7;BJ: 11.7;CAPAN-2: 5.3;fHDF/TERT166: 6.9" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 4 "cerebral cortex: 7.4;hippocampal formation: 17.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cerebral cortex: 23.5;hippocampal formation: 31.8;olfactory region: 11.0" "Low region specificity" "Detected in many" HPA038789 Uncertain "HPA038789: AB_10673475" "unprognostic (5.37e-2)" "unprognostic (4.65e-1)" "unprognostic (8.73e-2)" "unprognostic (7.75e-11)" "unprognostic (7.83e-3)" "unprognostic (1.54e-2)" "unprognostic (7.62e-2)" "unprognostic (7.82e-4)" "unprognostic (4.41e-3)" "unprognostic (8.37e-2)" "unprognostic (6.09e-2)" "unprognostic (7.24e-3)" "unprognostic (7.71e-7)" "unprognostic (5.21e-3)" "unprognostic (2.76e-1)" "unprognostic (6.01e-3)" "unprognostic (3.32e-5)" 2.5 1.1 1.9 0.5 2.8 0.3 1.0 0.1 7.4 9.1 2.4 1.4 1.1 0.6 4.7 1.8 0.9 3.5 1.2 0.4 17.7 1.7 0.5 0.4 2.9 1.5 0.5 1.1 1.0 1.2 0.4 0.0 0.7 2.9 8.8 1.0 0.0 0.8 6.0 1.2 0.4 0.8 1.6 0.5 3.6 2.5 1.5 0.0 0.0 0.9 0.0 0.4 3.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 11.7 2.1 0.8 0.2 0.5 5.3 0.0 0.0 6.9 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.4 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.8 0.1 7.4 17.7 1.7 0.5 1.1 2.9 0.0 ADRA2B "ADRA2L1, ADRA2RL1, ADRARL1" ENSG00000274286 "Adrenoceptor alpha 2B" P18089 2 96112875-96116245 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 5.2;EFO-21: 3.3;HAP1: 1.8;NTERA-2: 1.8;SCLC-21H: 1.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066029 Approved "HPA066029: " "unprognostic (6.16e-2)" "unprognostic (1.31e-2)" "unprognostic (1.76e-2)" "unprognostic (4.93e-4)" "unprognostic (1.84e-2)" "unprognostic (5.24e-2)" "unprognostic (6.80e-5)" "unprognostic (4.85e-2)" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (8.34e-2)" "unprognostic (2.54e-1)" "unprognostic (2.21e-1)" "unprognostic (4.43e-2)" "unprognostic (3.39e-1)" "unprognostic (1.36e-1)" "unprognostic (6.55e-2)" 4.9 2.2 0.3 0.4 2.2 1.2 8.1 0.1 0.7 4.5 4.0 1.9 0.2 0.5 1.3 7.5 4.3 0.8 3.2 6.1 0.5 2.9 7.5 0.3 0.2 4.4 0.0 5.0 2.3 1.0 0.0 1.3 3.3 3.3 0.4 0.9 1.8 2.9 8.0 0.3 1.2 2.1 0.6 4.8 0.7 2.6 1.9 0.0 2.1 1.8 0.0 3.8 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.3 0.0 0.3 1.8 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.1 1.8 0.3 0.0 0.0 0.4 0.0 0.3 1.4 0.0 0.0 1.2 0.0 0.3 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADRA2C "ADRA2L2, ADRA2RL2, ADRARL2" ENSG00000184160 "Adrenoceptor alpha 2C" P18825 4 3766348-3768526 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "cervix, uterine: 35.1" "Cell line enhanced" "Detected in some" "Hep G2: 11.0;MCF7: 18.2;NTERA-2: 6.4;SCLC-21H: 7.0;SH-SY5Y: 8.5;T-47d: 6.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "basal ganglia: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 41.4" HPA057688 Uncertain "HPA057688: " "unprognostic (1.44e-2)" "unprognostic (2.21e-3)" "unprognostic (1.23e-1)" "unprognostic (2.02e-2)" "unprognostic (4.70e-2)" "unprognostic (1.11e-1)" "unprognostic (7.12e-2)" "unprognostic (6.69e-2)" "unprognostic (1.88e-1)" "unprognostic (3.71e-1)" "unprognostic (3.24e-2)" "unprognostic (9.08e-3)" "unprognostic (1.01e-2)" "unprognostic (6.00e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (6.48e-2)" 6.5 2.4 2.1 1.0 9.8 0.4 9.2 0.5 2.6 35.1 1.5 0.6 12.8 1.0 20.3 18.0 2.1 6.4 5.5 3.0 1.2 1.0 9.2 1.3 2.0 1.2 0.7 1.6 7.6 4.1 0.5 4.2 27.6 1.1 7.3 0.6 3.6 0.8 24.6 2.6 2.1 0.9 3.0 0.7 7.5 0.7 6.2 2.0 0.2 0.8 1.9 0.5 2.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.1 0.5 0.0 0.2 0.4 0.0 0.0 0.0 2.0 1.2 0.0 2.1 0.3 0.0 0.2 0.0 0.0 0.0 5.6 0.0 0.0 11.0 0.6 0.0 0.8 0.9 0.4 0.0 0.0 0.0 0.4 0.0 2.7 18.2 0.0 0.0 6.4 0.0 0.0 5.9 0.0 0.0 0.3 7.0 8.5 2.5 0.0 0.1 6.0 0.1 0.0 0.0 4.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 9.8 0.5 1.4 1.2 1.0 0.7 1.6 1.1 2.0 ADRB1 ADRB1R ENSG00000043591 "Adrenoceptor beta 1" P08588 10 114044056-114046908 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 48.0;placenta: 41.7" "Cell line enhanced" "Detected in some" "HDLM-2: 10.0;THP-1: 6.8;TIME: 8.7;U-937: 5.1" "Cancer enriched" "Detected in many" 10 "prostate cancer: 12.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "myeloid DC: 1.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 10.0;basal ganglia: 7.3;cerebral cortex: 17.1;hippocampal formation: 11.3;thalamus: 6.9" "Low region specificity" "Detected in many" HPA067972 Enhanced "HPA067972: " "unprognostic (1.45e-3)" "unprognostic (1.18e-3)" "unprognostic (1.44e-1)" "unprognostic (4.92e-2)" "unprognostic (3.22e-1)" "unprognostic (8.88e-2)" "unprognostic (9.28e-2)" "unprognostic (3.52e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-2)" "unprognostic (2.77e-4)" "unprognostic (1.33e-1)" "unprognostic (7.80e-3)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.59e-2)" "unprognostic (1.44e-1)" 4.3 1.0 6.9 1.1 14.0 1.3 5.9 1.0 10.7 0.8 3.1 0.8 0.0 1.8 0.9 0.9 1.9 0.8 0.9 48.0 5.6 2.4 1.7 2.5 18.3 0.9 3.5 4.4 0.8 2.4 0.9 1.2 41.7 2.6 6.5 1.6 4.5 10.7 0.8 3.1 0.9 2.3 0.9 1.3 1.7 1.4 1.0 2.5 0.0 1.0 0.0 1.1 1.1 0.4 1.4 1.9 0.1 1.3 0.0 0.5 0.1 2.0 1.2 0.2 1.3 0.0 0.0 0.3 0.1 0.1 0.2 0.2 0.5 1.6 0.3 0.4 0.0 0.4 0.1 0.1 0.3 10.0 0.6 0.4 0.2 0.2 0.0 0.4 0.7 0.0 1.1 0.0 2.0 0.2 0.1 0.1 0.2 1.2 1.6 1.4 0.4 3.9 0.3 0.4 0.1 0.0 1.7 0.2 0.3 0.0 0.8 0.1 0.3 6.8 8.7 0.3 0.1 0.2 0.2 0.0 0.1 0.5 0.0 5.1 0.2 0.0 1.3 0.0 0.5 0.9 0.0 0.6 0.1 0.3 1.9 1.4 0.0 0.4 0.1 0.0 0.1 0.2 0.0 0.1 6.9 14.0 1.0 10.7 5.6 2.4 3.5 4.4 2.6 2.5 ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSG00000169252 "Adrenoceptor beta 2" P07550 5 148825245-148828687 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 34.6" "Cell line enhanced" "Detected in many" "hTCEpi: 24.0;hTERT-HME1: 25.0;PC-3: 10.3" "Low cancer specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003431, HPA075322" Uncertain Uncertain Cytosol Cytosol "HPA003431: AB_1845333, HPA075322: " "unprognostic (2.28e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (9.35e-3)" "unprognostic (5.54e-2)" "unprognostic (2.34e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-2)" "unprognostic (2.23e-1)" "prognostic favourable (3.15e-9)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" 11.7 0.2 0.7 0.9 0.4 4.6 13.8 0.0 0.3 6.1 0.9 0.3 0.9 0.2 6.4 1.4 1.1 2.8 0.7 0.3 0.2 6.0 8.5 1.1 0.9 0.0 0.0 0.5 0.0 4.0 3.8 0.7 3.3 0.1 4.4 15.9 1.3 1.2 1.0 3.7 2.9 0.0 0.5 2.0 2.3 5.4 4.8 6.1 14.0 10.8 7.3 34.6 9.6 7.5 0.0 0.0 0.0 0.3 0.0 0.0 1.4 4.3 2.0 2.2 0.0 3.2 0.0 2.1 0.4 6.7 0.0 9.1 2.3 0.0 0.2 0.0 1.6 0.0 0.2 0.0 3.8 0.0 24.0 0.6 25.0 0.9 0.0 2.8 5.2 0.0 0.0 4.1 0.1 10.3 2.2 1.4 4.2 1.0 1.9 0.0 0.0 1.8 0.1 0.6 0.0 2.3 4.0 0.0 1.7 2.4 1.1 0.7 0.0 0.1 0.0 4.9 0.8 3.5 4.7 14.0 34.6 7.8 25.7 4.8 8.2 20.9 5.3 3.0 1.4 12.9 7.6 7.3 10.8 6.1 0.4 9.6 ADRB3 ENSG00000188778 "Adrenoceptor beta 3" P13945 8 37962991-37966965 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 23.9;ovary: 15.7;smooth muscle: 10.8" "Cell line enhanced" "Detected in some" "HeLa: 2.3;Karpas-707: 1.0;U-2 OS: 1.3" "Not detected" "Not detected" "Region enhanced" "Detected in single" "amygdala: 1.3" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA061969 Uncertain "HPA061969: " "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (6.64e-3)" "unprognostic (5.41e-1)" "unprognostic (1.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-2)" "unprognostic (2.29e-8)" "unprognostic (1.10e-3)" "unprognostic (2.81e-2)" "unprognostic (5.37e-2)" "unprognostic (6.06e-3)" 0.4 0.1 1.3 1.9 0.3 0.3 0.3 0.0 0.8 1.6 2.3 0.0 0.0 0.4 0.9 1.9 1.7 5.3 23.9 0.1 0.2 0.1 0.1 0.0 0.2 1.2 0.0 0.0 15.7 0.0 0.0 0.0 4.7 0.0 4.1 0.4 0.0 0.0 0.1 0.0 0.1 0.9 10.8 0.0 0.0 3.0 0.2 0.0 0.0 0.0 0.0 0.1 9.9 1.5 0.9 0.2 1.2 0.4 0.8 0.5 0.0 0.2 0.2 0.1 0.1 0.2 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.3 0.0 0.3 0.0 0.1 0.1 0.0 0.0 2.3 0.4 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.1 0.4 0.3 0.4 1.3 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.0 1.0 0.3 0.3 0.1 0.1 0.4 0.7 0.2 0.1 0.0 0.9 0.2 0.2 1.2 0.8 0.4 0.2 0.5 0.0 1.3 0.3 0.0 0.8 0.2 0.1 0.0 0.0 0.0 0.0 AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 29.6;placenta: 44.9" "Cell line enhanced" "Detected in some" "ASC diff: 62.9;ASC TERT1: 8.8;BJ hTERT+ SV40 Large T+: 12.0;HBF TERT88: 18.9;HSkMC: 11.4" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003596 Enhanced Uncertain Vesicles Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" 18.8 11.6 0.0 0.1 0.0 0.0 10.8 0.0 0.0 0.8 5.5 0.0 0.6 0.5 0.5 2.2 1.6 3.1 0.0 0.1 5.7 29.6 2.6 0.0 0.9 0.8 0.6 0.6 0.8 44.9 1.3 1.0 1.0 1.0 2.9 4.4 0.7 1.1 0.0 2.3 1.7 0.2 4.1 0.0 4.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 62.9 8.8 0.0 0.0 1.3 12.0 6.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 1.1 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APLNR "AGTRL1, APJ, APJR, FLJ90771" ENSG00000134817 "Apelin receptor" P35414 11 57233577-57237314 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 63.8;lymphoid tissue: 44.1;placenta: 40.4" "Group enriched" "Detected in some" 19 "AF22: 10.1;HEL: 8.7;K-562: 2.6;NTERA-2: 3.0" "Cancer enhanced" "Detected in all" "glioma: 50.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" CAB025842 Approved "CAB025842: " "unprognostic (5.06e-2)" "unprognostic (3.56e-1)" "unprognostic (2.70e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-1)" "unprognostic (6.68e-3)" "unprognostic (1.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (4.72e-1)" "unprognostic (1.77e-3)" "unprognostic (3.27e-2)" "unprognostic (8.13e-2)" "unprognostic (1.13e-1)" "unprognostic (7.13e-3)" 8.4 2.1 26.1 3.8 14.2 0.0 3.3 3.8 21.0 1.2 2.3 30.8 0.0 1.8 1.6 0.0 1.8 1.2 5.7 7.2 24.8 9.3 2.5 8.0 3.5 4.0 17.3 10.2 1.2 1.4 1.9 1.5 40.4 32.8 1.2 2.8 0.2 1.7 0.8 5.8 3.0 1.7 4.7 63.8 44.1 1.5 1.2 18.2 0.1 3.1 0.6 1.8 3.8 1.5 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 26.1 14.2 3.8 16.3 24.8 9.3 17.3 10.2 32.8 18.2 AVPR1B AVPR3 ENSG00000198049 "Arginine vasopressin receptor 1B" P47901 1 206109692-206117699 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 23 "pituitary gland: 52.8" "Cell line enhanced" "Detected in single" "PC-3: 3.5" "Cancer enhanced" "Detected in some" "renal cancer: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075404 Enhanced "HPA075404: " "unprognostic (4.87e-2)" "unprognostic (1.44e-1)" "unprognostic (4.82e-1)" "unprognostic (2.82e-1)" "unprognostic (2.87e-1)" "unprognostic (1.08e-2)" "unprognostic (3.33e-1)" "unprognostic (2.96e-2)" "unprognostic (6.23e-2)" "unprognostic (7.65e-2)" "unprognostic (1.86e-1)" "unprognostic (6.66e-3)" 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.6 0.5 0.1 1.3 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 52.8 0.1 0.1 0.2 0.8 0.0 0.0 0.4 0.0 0.0 1.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.9 3.5 0.0 0.0 0.2 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96255824-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.1;lymphoid tissue: 17.1" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.6;HHSteC: 11.9;hTEC/SVTERT24-B: 11.1;U-2197: 12.3;U-87 MG: 40.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Cell type enriched" "Detected in single" 19 "T-reg: 1.8" "Lineage enriched" "Detected in single" 19 "T-cells: 1.8" "Low region specificity" "Detected in single" HPA002935 Approved "HPA002935: AB_1078274" "unprognostic (6.15e-2)" "unprognostic (2.78e-2)" "unprognostic (9.40e-2)" "unprognostic (3.06e-3)" "unprognostic (6.76e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-2)" "unprognostic (2.34e-3)" "unprognostic (2.23e-2)" "unprognostic (2.96e-2)" "unprognostic (4.80e-3)" "unprognostic (2.36e-1)" "unprognostic (9.96e-6)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-3)" "unprognostic (4.66e-2)" 7.3 0.0 0.2 17.1 0.2 0.0 0.8 2.1 0.6 5.4 3.7 0.2 0.2 1.8 0.7 2.8 10.4 4.8 16.1 2.3 0.2 0.0 2.4 0.6 3.7 0.2 0.2 0.2 4.5 7.9 0.0 0.2 3.0 0.4 2.2 2.8 0.7 1.5 1.1 0.4 2.4 3.7 5.7 0.2 0.6 3.3 2.3 0.2 0.2 0.8 4.6 2.0 13.7 5.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.6 0.0 0.4 1.1 3.9 0.0 1.0 11.6 1.2 0.2 0.0 0.2 0.0 0.0 6.7 1.1 0.0 0.1 1.9 0.1 0.0 0.0 1.1 0.0 11.9 0.0 0.0 0.4 0.9 11.1 0.2 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.1 0.0 0.4 0.0 3.2 1.1 0.0 0.0 0.0 0.0 4.4 0.2 12.3 0.6 2.1 4.0 0.0 40.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.2 2.1 0.6 0.2 0.0 0.2 0.2 0.4 0.2 BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 22.3;BJ hTERT+: 41.1;U-87 MG: 17.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 13.5;pons and medulla: 5.7" "Cell type enhanced" "Detected in single" "memory CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003551, HPA050841" Approved Supported "Plasma membrane" "Plasma membrane" "HPA003551: , HPA050841: " "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" 9.0 1.2 1.5 3.7 1.0 0.0 4.7 13.5 1.1 12.2 9.0 1.3 4.4 5.6 8.5 12.7 14.9 5.1 21.1 4.3 0.8 0.7 12.1 0.7 2.2 0.4 0.9 0.3 4.7 6.8 0.9 1.1 2.9 5.7 6.9 9.2 0.9 3.1 11.3 2.7 4.0 10.3 11.3 1.3 0.4 4.2 3.2 0.0 0.6 3.6 13.9 4.4 16.7 13.5 0.0 0.9 0.0 0.0 0.0 1.2 0.0 0.7 2.6 0.0 4.8 7.3 22.3 0.0 2.4 41.1 1.4 1.6 0.1 4.5 0.0 0.1 3.7 6.4 0.0 1.0 1.2 0.5 0.0 0.0 0.5 0.0 3.5 0.0 0.0 6.8 3.3 4.1 2.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.4 0.0 1.5 0.5 0.7 6.8 0.0 0.4 0.0 0.0 0.1 0.1 1.4 0.0 0.1 0.0 0.0 17.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.5 1.0 13.5 1.1 0.8 0.7 0.9 0.3 5.7 0.0 C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8058302-8066471 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 101.1" "Cell line enriched" "Detected in some" 9 "HMC-1: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 101.1;eosinophil: 56.9;intermediate monocyte: 34.5;non-classical monocyte: 47.0" "Group enriched" "Detected in many" 18 "granulocytes: 101.1;monocytes: 47.0" "Low region specificity" "Detected in many" CAB009405 Enhanced "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" 34.1 10.0 11.7 35.1 15.5 17.4 10.7 1.9 7.6 7.2 5.8 15.5 0.7 4.9 4.8 6.7 3.8 7.3 15.0 7.3 9.7 7.2 9.2 10.0 21.1 29.7 16.7 3.5 4.9 5.5 2.9 3.5 19.8 13.3 4.8 6.4 5.2 7.8 4.0 3.6 2.7 9.1 13.9 23.4 25.2 4.9 5.8 16.2 1.9 3.2 1.5 4.8 12.9 3.7 0.0 4.0 101.1 47.0 0.5 3.8 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.2 1.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.5 7.6 65.8 0.3 0.0 0.1 0.2 0.2 1.5 3.8 0.2 0.0 0.3 2.7 0.0 0.0 0.0 1.4 7.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.3 0.2 0.2 0.0 0.1 0.1 0.0 0.2 4.2 2.9 0.1 101.1 13.6 56.9 2.9 34.5 3.8 0.0 1.5 2.0 4.0 0.0 0.3 1.2 1.8 0.5 47.0 0.3 1.5 7.8 11.7 15.5 1.9 7.6 9.7 7.2 16.7 3.5 13.3 16.2 C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 75.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 5.8;HMC-1: 7.4;U-87 MG: 8.8;U-937: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 75.8" "Group enriched" "Detected in many" 42 "granulocytes: 75.8;monocytes: 20.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Supported Vesicles Vesicles "CAB002720: , HPA014520: AB_1846337, HPA048012: " "unprognostic (5.95e-2)" "prognostic favourable (4.71e-4)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-2)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "prognostic unfavourable (9.55e-4)" "unprognostic (2.02e-1)" "unprognostic (9.56e-2)" "prognostic unfavourable (1.16e-4)" "unprognostic (1.96e-3)" "prognostic unfavourable (7.99e-4)" "unprognostic (1.82e-2)" "unprognostic (6.54e-2)" 33.7 8.0 1.9 34.9 7.0 46.2 8.7 0.7 3.0 5.6 6.0 3.7 1.6 1.0 4.1 4.9 3.5 14.3 16.5 11.7 7.6 3.2 5.3 9.1 38.1 26.9 3.8 1.2 7.6 3.6 1.3 27.9 12.8 10.9 4.2 1.9 7.8 2.9 1.1 7.0 1.1 3.0 11.4 11.2 48.8 4.2 6.3 1.3 2.3 2.5 1.7 3.4 12.2 2.7 0.1 1.1 75.8 20.5 0.1 0.1 2.6 1.4 5.3 0.3 0.5 1.0 0.4 1.1 1.0 0.6 0.3 0.1 0.2 5.8 0.4 1.1 1.2 2.0 0.7 0.8 0.2 1.0 0.7 0.2 4.9 0.8 0.6 2.6 7.4 0.8 3.0 0.6 0.9 0.0 0.3 2.6 0.2 1.5 0.3 3.4 1.8 0.8 0.3 0.1 0.4 1.8 1.2 0.0 0.1 0.5 0.5 0.8 0.4 3.0 0.0 0.1 3.1 0.4 0.3 0.4 0.4 0.3 8.8 8.9 0.3 7.0 8.9 6.9 0.1 15.1 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 75.8 0.1 20.5 0.2 0.0 2.6 1.9 7.0 0.7 3.0 7.6 3.2 3.8 1.2 10.9 1.3 C5AR2 "C5L2, GPR77" ENSG00000134830 "Complement component 5a receptor 2" Q9P296 19 47332147-47347327 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 21.1;lymphoid tissue: 17.3" "Group enriched" "Detected in some" 5 "MCF7: 16.7;T-47d: 20.7" "Cancer enhanced" "Detected in many" "breast cancer: 3.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 9.4;eosinophil: 7.0;neutrophil: 21.1" "Lineage enriched" "Detected in many" 8 "granulocytes: 21.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA016629 Uncertain "HPA016629: AB_1849312" "unprognostic (5.00e-2)" "unprognostic (2.31e-2)" "unprognostic (4.33e-2)" "unprognostic (2.00e-6)" "unprognostic (2.88e-1)" "unprognostic (1.13e-2)" "unprognostic (1.02e-2)" "unprognostic (2.13e-1)" "unprognostic (2.25e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (6.05e-2)" "unprognostic (3.73e-5)" "unprognostic (1.16e-2)" "unprognostic (7.42e-2)" "unprognostic (1.34e-1)" "unprognostic (6.88e-3)" 7.2 1.7 1.1 7.4 1.6 9.2 4.7 0.3 3.5 2.0 1.9 1.7 0.0 0.9 1.5 4.1 3.3 2.8 2.9 3.2 3.6 1.0 2.4 3.1 7.5 6.8 1.3 2.2 2.0 1.4 0.4 1.4 3.9 2.9 0.8 0.9 1.9 1.9 0.6 0.8 2.2 2.0 1.8 4.5 17.3 1.6 3.8 0.3 0.0 1.4 4.4 13.6 5.6 2.0 0.3 0.4 21.1 2.7 0.2 0.4 0.4 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.1 3.9 0.1 0.0 0.7 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 16.7 0.0 1.9 0.2 0.0 0.2 0.2 2.2 0.1 0.3 0.2 0.1 0.0 0.1 0.0 20.7 0.2 0.1 0.7 0.2 0.4 0.1 0.3 0.2 0.7 0.7 1.2 0.1 9.4 1.7 7.0 0.2 1.5 0.2 0.2 0.1 0.1 0.4 0.3 0.1 0.1 21.1 0.2 2.7 0.2 0.4 0.4 1.1 1.6 0.3 3.5 3.6 1.0 1.3 2.2 2.9 0.3 CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187343129-187448460 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 91.0" "Cell line enriched" "Detected in some" 4 "HUVEC TERT2: 61.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 3.3;myeloid DC: 11.2;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 6 "dendritic cells: 11.2;monocytes: 3.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" "Plasma membrane" "HPA008070: AB_1845912, HPA046515: " "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" 42.4 5.2 4.9 6.4 3.8 0.2 19.6 7.3 9.4 21.2 12.6 2.6 4.0 3.1 17.9 6.8 16.3 6.5 13.4 15.1 4.5 3.8 16.5 12.5 91.0 16.9 4.7 3.5 15.2 3.7 8.2 5.3 6.4 7.5 10.7 5.3 7.5 8.4 4.4 5.0 4.2 5.6 14.5 18.1 9.1 5.0 7.9 2.8 2.3 16.9 11.8 4.7 10.6 14.0 0.2 11.2 0.1 3.3 1.2 1.1 1.1 0.0 0.0 3.1 0.0 2.3 0.5 0.0 0.2 0.4 0.0 0.3 0.0 0.3 0.0 0.8 0.2 0.0 0.0 0.2 0.0 0.4 0.2 0.5 0.0 0.0 1.7 0.0 0.0 1.6 0.1 0.1 0.7 61.0 0.0 0.8 0.4 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.1 14.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.8 0.2 0.0 0.0 0.1 2.2 0.0 0.2 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.6 0.0 0.2 0.0 0.0 11.2 0.0 1.1 0.2 0.1 1.2 1.2 3.3 0.0 1.1 4.9 3.8 7.3 3.7 4.5 3.8 4.7 3.5 7.5 2.8 CASR "FHH, GPRC2A, HHC, HHC1, NSHPT" ENSG00000036828 "Calcium sensing receptor" P41180 3 122183683-122291629 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "parathyroid gland: 155.3" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 4.0" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 5.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA039686, HPA050335" Enhanced "HPA039686: AB_10673536, HPA050335: AB_2681092" "unprognostic (1.97e-2)" "unprognostic (7.40e-2)" "unprognostic (8.20e-4)" "unprognostic (3.15e-1)" "unprognostic (8.55e-4)" "unprognostic (1.58e-1)" "unprognostic (7.32e-2)" "unprognostic (7.67e-2)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (1.91e-5)" "unprognostic (2.72e-1)" "unprognostic (2.26e-1)" "unprognostic (1.24e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.4 0.0 0.1 0.0 0.0 0.0 0.0 21.0 0.0 0.1 0.2 18.1 0.5 0.0 0.0 0.1 0.0 0.6 12.1 155.3 0.6 0.0 0.2 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.6 0.3 0.2 0.2 0.5 0.3 0.0 0.1 1.6 0.0 0.1 0.7 0.0 1.4 0.5 1.1 0.3 0.8 1.1 0.2 0.6 1.3 0.7 1.1 0.3 0.3 0.7 0.7 0.0 0.0 0.1 0.6 0.8 1.1 0.9 0.4 0.5 0.2 0.2 0.3 0.8 0.1 1.4 1.1 1.1 0.0 0.7 0.8 0.4 0.4 0.4 0.2 0.2 0.6 2.0 0.3 0.7 0.5 0.9 1.4 0.6 0.6 0.5 0.6 4.0 1.5 0.6 0.8 0.9 0.5 0.3 0.9 0.3 1.3 1.0 1.8 1.0 0.3 1.6 1.1 0.5 0.7 0.6 1.0 1.0 0.3 0.1 0.9 0.2 0.9 0.7 0.9 0.9 0.1 1.4 0.7 0.6 1.1 0.8 0.2 0.5 1.1 0.2 0.0 0.0 0.0 0.6 0.1 0.2 0.1 0.0 0.2 0.0 CCR10 GPR2 ENSG00000184451 "C-C motif chemokine receptor 10" P46092 17 42678889-42683917 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 31.1" "Cell line enhanced" "Detected in some" "Karpas-707: 8.6;RPMI-8226: 6.2;U-266/70: 17.7;U-266/84: 8.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 31.1" "Group enriched" "Detected in many" 9 "dendritic cells: 10.9;T-cells: 31.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB011684, HPA048007, HPA069188" Uncertain Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB011684: AB_731502, HPA048007: , HPA069188: " "unprognostic (3.25e-2)" "unprognostic (2.71e-2)" "unprognostic (5.70e-2)" "unprognostic (2.41e-2)" "unprognostic (5.25e-2)" "unprognostic (2.23e-3)" "unprognostic (5.18e-4)" "unprognostic (1.15e-1)" "unprognostic (9.55e-2)" "unprognostic (1.56e-1)" "unprognostic (1.21e-3)" "unprognostic (1.01e-2)" "unprognostic (2.32e-11)" "unprognostic (2.84e-2)" "unprognostic (1.53e-1)" "unprognostic (1.88e-2)" "unprognostic (1.87e-1)" 10.0 5.4 5.7 4.8 5.3 0.7 3.0 7.3 7.3 3.9 9.7 0.9 1.5 5.1 5.8 1.4 1.5 4.5 1.5 2.5 3.5 5.0 1.6 0.5 2.2 12.5 1.9 5.0 5.2 2.6 0.4 14.0 2.3 4.1 2.1 1.0 1.1 4.0 2.0 9.1 1.1 8.7 1.8 4.4 4.3 5.0 2.2 1.2 0.5 1.5 0.3 3.6 1.0 2.0 2.3 10.9 0.1 0.3 0.0 31.1 0.7 0.5 0.8 1.1 4.9 0.3 0.8 1.1 2.4 0.5 0.2 0.4 0.7 0.3 0.1 0.3 0.3 0.9 0.0 0.1 0.1 2.3 1.2 0.0 3.1 0.4 0.7 0.0 0.3 0.8 0.0 0.4 0.0 0.1 2.6 8.6 0.0 0.3 0.1 2.3 0.6 1.2 0.6 0.2 6.2 1.1 0.0 0.8 1.1 0.7 0.0 0.2 0.8 0.9 2.4 2.9 0.6 0.9 0.3 17.7 8.0 2.5 1.4 0.7 0.9 0.0 0.3 0.1 0.2 0.0 0.1 2.3 5.2 2.6 0.2 2.1 0.6 0.8 0.0 0.0 0.1 10.9 31.1 0.7 5.7 5.3 7.3 7.3 3.5 5.0 1.9 5.0 4.1 1.2 CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353734-46360928 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood: 96.3;lymphoid tissue: 36.1" "Cell line enhanced" "Detected in some" "Karpas-707: 47.4;THP-1: 22.5;U-266/70: 109.2;U-266/84: 43.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "basophil: 96.3" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" CAB003793 Approved "CAB003793: AB_344889" "unprognostic (1.09e-2)" "unprognostic (6.28e-4)" "unprognostic (3.49e-2)" "unprognostic (6.35e-4)" "unprognostic (1.89e-2)" "unprognostic (4.16e-4)" "unprognostic (8.06e-2)" "prognostic favourable (5.87e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (4.88e-2)" "unprognostic (4.19e-1)" 2.5 1.3 0.6 20.7 0.8 0.9 1.9 0.5 0.8 4.3 5.8 0.5 1.5 5.6 2.6 2.4 6.1 2.2 2.5 1.8 0.6 0.6 3.7 1.8 8.6 30.1 1.6 0.1 1.7 1.7 0.0 0.8 2.1 1.8 3.7 4.0 2.6 10.2 3.5 0.8 1.3 7.3 5.6 1.5 36.1 3.7 1.5 0.5 3.6 2.0 3.5 5.9 5.8 1.7 1.6 29.0 96.3 28.4 2.5 19.3 13.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 109.2 43.5 0.0 0.0 0.8 0.0 96.3 28.4 0.4 2.5 2.6 19.3 1.6 5.2 4.2 29.0 0.3 0.1 0.1 0.7 2.5 0.0 23.0 2.3 13.5 0.6 0.8 0.5 0.8 0.6 0.6 1.6 0.1 1.8 0.5 CCR3 "CC-CKR-3, CD193, CKR3, CMKBR3" ENSG00000183625 "C-C motif chemokine receptor 3" P51677 3 46163604-46266706 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "blood: 175.9" "Cell line enriched" "Detected in some" 9 "RPMI-8226: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 22 "basophil: 175.9;eosinophil: 152.0" "Lineage enriched" "Detected in many" 92 "granulocytes: 175.9" "Not detected" "Not detected" "Not detected" "Not detected" CAB003795 Uncertain "CAB003795: AB_562259" "unprognostic (1.56e-2)" "unprognostic (6.65e-3)" "unprognostic (1.01e-1)" "unprognostic (3.98e-2)" "unprognostic (1.41e-1)" "unprognostic (3.25e-3)" "unprognostic (3.11e-7)" "unprognostic (4.36e-2)" "unprognostic (3.35e-2)" "unprognostic (3.43e-2)" "unprognostic (4.81e-2)" "unprognostic (3.94e-2)" "unprognostic (3.17e-6)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (2.41e-1)" "unprognostic (9.81e-2)" 0.6 0.2 0.3 2.9 1.1 0.4 0.3 0.2 0.8 0.3 1.3 0.2 0.2 2.9 0.8 0.2 0.4 0.5 1.3 0.3 0.2 0.2 0.5 1.2 5.8 0.6 0.3 0.2 0.2 0.3 0.0 0.3 7.0 0.7 1.0 1.4 0.9 2.4 0.2 3.2 3.6 5.1 1.6 0.5 2.7 2.2 0.4 0.2 0.6 1.8 2.8 0.6 4.0 0.3 0.0 0.2 175.9 0.0 0.0 1.9 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 2.2 0.0 0.7 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.1 0.3 0.1 0.0 0.2 0.0 24.9 0.0 2.0 0.1 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.1 2.7 2.1 0.0 0.0 0.5 0.0 175.9 0.0 152.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.2 1.9 0.3 0.3 1.1 0.2 0.8 0.2 0.2 0.3 0.2 0.7 0.2 CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951574-32956349 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 28.9;lymphoid tissue: 57.1" "Cell line enriched" "Detected in some" 17 "HDLM-2: 65.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "T-reg: 28.9" "Lineage enriched" "Detected in single" 48 "T-cells: 28.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031613 Approved Supported "Plasma membrane" "Plasma membrane" "HPA031613: AB_10601096" "unprognostic (4.63e-3)" "unprognostic (8.70e-3)" "unprognostic (2.82e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (4.59e-7)" "unprognostic (3.02e-1)" "unprognostic (5.05e-3)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (5.53e-4)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" 1.5 0.6 0.3 12.6 0.4 1.5 1.1 0.3 0.3 1.1 1.1 0.1 0.7 0.4 1.0 0.6 1.6 0.8 3.8 0.8 0.3 0.3 1.8 0.9 6.0 24.1 0.3 0.0 0.5 0.5 0.5 0.5 0.1 0.1 1.5 1.2 0.8 4.3 0.2 1.8 2.2 5.0 0.4 0.4 10.2 1.3 2.7 0.0 57.1 1.3 2.8 29.7 8.6 1.1 0.2 0.2 0.5 0.1 0.1 28.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 65.5 0.0 3.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.2 0.1 0.2 0.1 6.0 1.8 0.0 0.2 0.1 0.1 0.5 0.1 0.1 0.2 28.9 0.8 0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.0 0.1 0.0 CCR6 "BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22" ENSG00000112486 "C-C motif chemokine receptor 6" P51684 6 167111807-167139696 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 30.7;intestine: 9.9;lymphoid tissue: 33.7" "Cell line enriched" "Detected in some" 5 "Hep G2: 14.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "MAIT T-cell: 30.7;memory B-cell: 23.8;memory CD4 T-cell: 11.9;naive B-cell: 28.2;T-reg: 20.9" "Group enriched" "Detected in many" 5 "B-cells: 28.2;T-cells: 30.7" "Region enriched" "Detected in single" 8 "basal ganglia: 0.9" "Not detected" "Not detected" "CAB006820, HPA014488" Approved "CAB006820: , HPA014488: AB_1846639" "unprognostic (1.12e-2)" "unprognostic (2.92e-2)" "unprognostic (2.07e-3)" "unprognostic (2.08e-1)" "unprognostic (8.43e-2)" "unprognostic (2.05e-4)" "unprognostic (2.39e-1)" "unprognostic (4.98e-3)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (4.19e-2)" "unprognostic (4.26e-2)" "unprognostic (2.68e-4)" "unprognostic (3.74e-2)" "unprognostic (7.96e-2)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" 0.5 0.3 1.0 24.4 1.5 1.3 1.1 0.3 1.1 0.6 3.0 0.1 0.0 1.4 0.3 0.8 2.1 0.5 3.1 0.3 0.9 0.9 1.0 0.5 3.3 27.3 0.6 0.0 0.3 0.3 0.0 0.4 0.5 0.2 0.5 1.2 0.3 5.0 0.8 0.3 1.1 9.9 0.0 0.4 23.4 2.2 2.7 0.1 3.7 0.6 2.1 33.7 4.8 0.4 28.2 5.4 0.2 0.0 0.4 30.7 2.5 0.1 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.5 0.2 1.3 0.3 0.0 0.0 0.3 0.2 0.1 2.6 0.7 0.1 0.3 14.1 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.2 0.1 0.0 0.2 0.2 0.2 0.4 0.0 0.8 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.1 0.3 0.5 0.3 0.4 0.0 0.2 0.6 0.0 0.0 0.1 1.6 0.0 30.7 23.8 11.9 4.7 5.4 28.2 0.1 0.0 0.2 0.4 0.0 0.6 20.9 2.5 1.0 1.5 0.3 1.1 0.9 0.9 0.6 0.0 0.2 0.1 CCR7 "BLR2, CD197, CDw197, CMKBR7, EBI1" ENSG00000126353 "C-C motif chemokine receptor 7" P32248 17 40553769-40565472 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "blood: 252.3;lymphoid tissue: 110.6" "Cell line enriched" "Detected in some" 79 "HDLM-2: 171.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 252.3" "Lineage enriched" "Detected in many" 4 "T-cells: 252.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003796, HPA031383, HPA074467" Enhanced Approved Mitochondria Mitochondria "CAB003796: AB_562261, HPA031383: , HPA074467: " "prognostic favourable (3.84e-4)" "prognostic favourable (8.03e-6)" "unprognostic (2.26e-3)" "unprognostic (1.32e-3)" "unprognostic (2.35e-3)" "prognostic favourable (7.61e-7)" "unprognostic (2.71e-4)" "unprognostic (2.58e-2)" "unprognostic (4.48e-2)" "unprognostic (4.68e-4)" "unprognostic (1.10e-2)" "unprognostic (3.11e-1)" "unprognostic (1.08e-3)" "unprognostic (3.12e-1)" "prognostic unfavourable (7.72e-4)" "unprognostic (1.02e-1)" "unprognostic (7.95e-2)" 2.8 0.4 0.2 26.0 0.2 5.2 1.7 0.2 0.3 2.2 1.2 0.3 0.8 0.3 1.2 0.5 1.4 2.3 2.0 1.9 0.2 0.2 1.5 1.7 3.4 110.6 0.3 0.2 1.5 0.3 0.0 1.0 1.0 0.4 1.3 2.1 0.7 8.4 0.2 0.2 1.1 16.2 0.2 0.4 20.3 1.8 1.2 0.3 57.1 2.0 1.2 53.8 4.2 1.3 58.8 2.9 2.3 0.3 44.1 252.3 109.3 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 171.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.9 0.1 1.1 0.2 0.0 0.0 1.1 0.3 0.2 3.1 0.1 3.6 37.2 53.3 15.3 0.2 58.8 252.3 133.9 2.3 44.1 0.2 2.9 30.3 109.3 0.2 0.2 0.2 0.3 0.2 0.2 0.3 0.2 0.4 0.3 CCR8 "CDw198, CKR-L1, CMKBR8, CMKBRL2, CY6, GPR-CY6, TER1" ENSG00000179934 "C-C motif chemokine receptor 8" P51685 3 39329706-39333511 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood: 19.8;lymphoid tissue: 19.3;urinary bladder: 5.3" "Cell line enriched" "Detected in some" 22 "HDLM-2: 48.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "T-reg: 19.8" "Lineage enriched" "Detected in single" 30 "T-cells: 19.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042383 Enhanced "HPA042383: " "unprognostic (2.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.38e-2)" "unprognostic (7.63e-4)" "unprognostic (3.31e-1)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (3.37e-2)" "unprognostic (7.40e-2)" "unprognostic (2.99e-1)" "unprognostic (4.65e-8)" "unprognostic (7.96e-2)" "unprognostic (2.24e-2)" "unprognostic (2.56e-1)" "unprognostic (4.14e-1)" 0.3 0.2 0.2 3.1 0.2 0.0 0.3 0.2 0.2 0.3 0.5 0.1 0.1 0.0 0.3 0.1 0.8 0.1 2.1 0.2 0.2 0.2 0.5 0.3 1.4 2.8 0.1 0.1 0.2 0.3 0.0 0.2 0.1 0.1 0.4 1.3 0.1 0.5 0.1 0.2 1.0 1.2 0.1 0.4 1.7 0.8 0.3 0.1 19.3 0.4 1.2 3.5 5.3 0.3 0.0 0.0 0.0 0.0 0.6 19.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 1.8 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 19.8 0.6 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.1 0.1 CCR9 "CDw199, GPR-9-6, GPR28" ENSG00000173585 "C-C motif chemokine receptor 9" P51686 3 45886504-45903177 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 130.2" "Cell line enriched" "Detected in single" 324 "MOLT-4: 48.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 17.5;naive B-cell: 9.2;T-reg: 5.7" "Group enriched" "Detected in many" 42 "B-cells: 17.5;T-cells: 5.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" CAB006839 Uncertain "CAB006839: " "unprognostic (3.08e-3)" "unprognostic (3.37e-1)" "unprognostic (5.56e-2)" "unprognostic (1.78e-1)" "unprognostic (8.65e-3)" "unprognostic (7.88e-3)" "unprognostic (4.54e-1)" "unprognostic (2.94e-2)" "unprognostic (3.00e-1)" "unprognostic (1.77e-1)" "unprognostic (8.06e-2)" "unprognostic (1.16e-1)" "unprognostic (2.59e-2)" "unprognostic (1.88e-1)" "unprognostic (4.34e-1)" "unprognostic (2.27e-1)" "unprognostic (7.20e-3)" 0.1 0.1 0.1 1.8 0.1 0.7 0.1 0.1 0.3 0.1 2.2 0.1 0.1 7.0 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.2 0.2 0.8 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.3 0.1 0.1 0.2 0.2 0.1 10.7 0.1 0.2 2.2 0.3 0.1 0.1 130.2 0.1 0.1 0.7 0.1 0.1 17.5 0.2 0.0 0.0 0.0 5.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 17.5 2.2 1.8 0.2 9.2 0.3 0.1 0.0 0.0 0.0 0.2 5.7 1.8 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407163-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.4" "Cell line enhanced" "Detected in some" "HEL: 16.3;PC-3: 12.6;RT4: 6.5;TIME: 12.3;U-266/84: 6.7;U-87 MG: 6.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043238 Approved "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favourable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favourable (9.67e-5)" 31.4 1.4 1.3 9.2 1.5 6.0 9.0 0.6 1.2 1.8 9.5 0.9 2.8 9.5 3.5 1.4 1.8 1.3 4.5 2.3 1.5 1.3 2.0 3.4 13.7 4.3 1.9 0.9 2.3 4.8 0.3 1.3 3.9 1.8 2.4 8.8 1.7 1.4 0.7 2.6 1.1 16.9 1.9 2.9 11.2 4.5 2.3 1.2 9.4 1.9 1.3 3.0 3.6 3.5 2.5 7.7 5.6 16.7 5.4 3.9 3.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 3.7 0.0 16.3 0.0 0.0 0.0 1.0 0.2 0.0 0.0 4.2 0.2 5.9 2.2 0.1 4.2 0.0 1.3 2.1 0.0 12.6 0.3 0.2 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 2.7 12.3 0.5 0.2 0.6 0.2 0.0 6.7 0.2 6.4 5.0 0.0 5.6 12.1 3.2 2.4 16.7 2.9 1.4 1.4 3.9 7.7 2.5 0.9 2.2 2.0 5.4 7.8 2.4 3.7 3.6 1.3 1.5 0.6 1.2 1.5 1.3 1.9 0.9 1.8 1.2 CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537170 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 23.8;HaCaT: 15.0;T-47d: 17.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 4 "memory B-cell: 3.0;naive B-cell: 3.0" "Lineage enriched" "Detected in single" 4 "B-cells: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Supported "Plasma membrane" "Plasma membrane" "HPA052976: , HPA060521: " "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" 3.4 0.5 0.6 5.0 1.4 0.3 4.1 0.4 0.3 8.7 1.3 0.9 3.6 0.3 5.7 7.5 14.2 11.1 5.3 4.6 0.7 0.7 16.2 0.8 19.3 4.2 0.4 0.0 6.0 2.6 7.5 3.8 3.4 2.2 7.2 0.4 3.8 22.6 3.0 0.3 13.9 2.3 3.1 0.4 1.8 3.6 2.8 0.0 1.8 5.7 12.7 12.8 3.1 5.0 3.0 0.2 0.0 0.0 0.7 0.1 0.0 8.5 23.8 4.5 3.9 0.0 0.0 2.1 0.7 1.5 1.4 0.3 5.7 6.7 0.0 11.8 0.1 15.0 3.7 11.4 0.5 0.0 4.6 0.0 9.5 0.2 0.2 1.5 0.6 0.0 10.6 0.0 9.5 0.0 0.0 0.0 0.0 10.8 0.0 1.7 1.7 3.8 0.0 0.0 2.8 6.3 5.3 0.2 0.3 7.4 6.0 1.2 17.0 5.0 0.3 0.0 0.1 0.0 0.1 4.5 0.2 2.4 5.9 0.0 5.1 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.6 1.4 0.4 0.3 0.7 0.7 0.4 0.0 2.2 0.0 CELSR2 "ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3" ENSG00000143126 "Cadherin EGF LAG seven-pass G-type receptor 2" Q9HCU4 1 109250019-109275750 "G-protein coupled receptors, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.7;skin 1: 27.8" "Cell line enhanced" "Detected in many" "AF22: 24.7;HaCaT: 24.4;MCF7: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013952 Uncertain Approved Cytosol Cytosol "HPA013952: AB_1846518" "unprognostic (4.46e-3)" "unprognostic (1.07e-2)" "unprognostic (3.00e-2)" "unprognostic (4.71e-2)" "unprognostic (2.19e-1)" "unprognostic (5.30e-2)" "unprognostic (3.51e-2)" "unprognostic (2.98e-1)" "unprognostic (1.33e-1)" "unprognostic (1.59e-2)" "unprognostic (1.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.94e-2)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-2)" "unprognostic (5.16e-2)" 1.5 2.3 12.6 1.1 16.0 0.9 5.4 9.2 31.7 6.9 1.8 13.7 3.4 1.4 3.1 4.3 10.9 18.8 1.8 5.3 17.1 8.1 5.6 1.2 1.8 1.3 10.0 15.4 1.2 4.8 7.8 2.3 1.6 8.3 3.5 1.4 5.4 6.4 10.4 9.3 27.8 1.5 2.4 14.1 1.0 2.0 11.0 8.6 0.5 10.9 2.7 3.2 2.3 6.1 0.0 0.1 0.0 0.0 0.0 0.6 0.1 6.8 6.4 24.7 4.5 0.0 0.0 6.7 0.8 0.6 1.5 0.4 1.0 0.2 1.2 5.6 0.5 24.4 6.4 3.9 0.8 0.1 2.6 0.5 5.9 1.4 0.5 0.3 3.2 0.1 9.6 0.6 0.4 0.3 4.0 0.3 0.0 28.1 0.7 0.3 8.0 1.2 6.2 2.2 0.3 5.4 2.3 10.0 4.7 3.8 8.3 5.3 7.8 1.5 0.0 0.0 4.5 0.4 6.1 1.6 0.4 0.3 1.3 0.5 2.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.6 16.0 9.2 31.7 17.1 8.1 10.0 15.4 8.3 8.6 CELSR3 "ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2" ENSG00000008300 "Cadherin EGF LAG seven-pass G-type receptor 3" Q9NYQ7 3 48636469-48662915 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7;pituitary gland: 11.2" "Cell line enhanced" "Detected in many" "HDLM-2: 12.9;SH-SY5Y: 14.7;SiHa: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 4 "T-cells: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062866 Approved "HPA062866: " "unprognostic (7.80e-2)" "unprognostic (3.80e-2)" "unprognostic (4.89e-1)" "unprognostic (9.12e-4)" "unprognostic (1.51e-1)" "unprognostic (1.59e-6)" "unprognostic (3.61e-6)" "unprognostic (1.86e-1)" "unprognostic (1.46e-3)" "unprognostic (5.07e-2)" "unprognostic (2.13e-3)" "unprognostic (2.87e-3)" "unprognostic (3.26e-3)" "unprognostic (9.53e-2)" "unprognostic (1.42e-1)" "unprognostic (3.86e-2)" "unprognostic (1.73e-1)" 0.7 4.0 10.9 1.2 8.3 1.7 0.8 19.7 11.1 0.6 1.3 0.0 0.0 1.2 0.8 1.2 0.6 0.7 0.7 0.5 7.1 1.4 0.6 0.6 0.8 1.4 2.0 10.4 0.9 2.6 1.4 11.2 1.0 3.6 0.7 1.2 1.4 0.6 0.8 0.5 1.2 1.3 0.8 3.3 1.0 2.1 5.4 1.4 0.0 0.9 0.0 1.0 0.7 0.7 0.3 0.1 0.0 0.1 0.2 1.5 0.4 3.8 2.9 4.8 2.8 0.6 0.9 1.2 0.2 0.5 0.6 0.9 5.4 2.9 0.8 0.7 0.2 0.4 1.5 0.2 0.3 12.9 0.8 1.3 11.1 1.9 0.9 1.2 2.1 0.4 3.8 0.3 6.9 0.0 0.5 3.9 0.9 4.1 0.1 0.0 2.7 1.3 0.3 0.7 4.0 0.0 2.6 10.8 14.7 12.9 0.3 0.5 6.4 2.5 0.0 4.8 4.6 6.2 2.3 0.3 7.0 3.4 3.4 0.9 7.4 0.0 0.1 0.0 1.0 0.0 0.2 0.3 0.2 0.2 0.1 0.0 0.3 1.5 0.0 0.2 0.0 0.0 1.1 0.4 10.9 8.3 19.7 11.1 7.1 1.4 2.0 10.4 3.6 1.4 CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 34.7;prostate: 28.2;salivary gland: 25.3" "Cell line enhanced" "Detected in some" "MCF7: 8.0;SK-BR-3: 4.0;T-47d: 2.6;WM-115: 1.4" "Cancer enriched" "Detected in some" 16 "prostate cancer: 27.9" "Group enriched" "Detected in many" 10 "amygdala: 13.2;basal ganglia: 22.0;cerebral cortex: 34.7;hippocampal formation: 14.2;olfactory region: 14.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "amygdala: 74.1;basal ganglia: 65.6;cerebral cortex: 83.5;hippocampal formation: 100.4;olfactory region: 36.8" "HPA014101, CAB022366" Enhanced Supported Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB022366: , HPA014101: AB_1854210" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-1)" "unprognostic (8.57e-4)" "unprognostic (4.88e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" 0.5 3.7 13.2 0.8 22.0 0.5 3.2 0.2 34.7 0.6 1.3 0.5 0.0 1.0 0.7 0.6 0.8 0.8 0.7 0.6 14.2 1.7 0.7 0.6 2.9 0.6 1.4 14.0 0.5 1.2 1.0 0.1 0.8 0.1 28.2 1.3 1.3 25.3 0.6 0.6 2.6 1.3 0.6 0.3 0.6 1.9 0.6 1.8 0.0 0.8 0.0 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.0 0.7 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 22.0 0.2 34.7 14.2 1.7 1.4 14.0 0.1 1.8 CHRM2 ENSG00000181072 "Cholinergic receptor muscarinic 2" P08172 7 136868669-137020255 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 25.5;heart muscle: 35.0;smooth muscle: 32.8" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 43.7" "Cancer enhanced" "Detected in single" "stomach cancer: 0.8" "Region enhanced" "Detected in many" "pons and medulla: 15.7" "Cell type enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022338, HPA029795" Approved "CAB022338: , HPA029795: AB_10601357" "unprognostic (3.51e-2)" "unprognostic (3.73e-4)" "unprognostic (5.77e-2)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.00e-1)" "unprognostic (2.69e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-1)" "unprognostic (1.35e-3)" 0.8 0.9 3.6 7.2 1.9 0.3 0.8 0.8 6.0 0.9 8.9 0.0 0.0 0.9 0.8 0.3 0.8 0.8 25.5 35.0 0.9 0.9 0.8 1.2 1.0 0.2 0.9 2.2 0.8 0.8 0.2 0.9 1.7 15.7 5.4 3.9 0.0 0.8 0.2 0.8 0.8 3.7 32.8 5.0 0.8 2.7 2.3 1.5 0.0 0.8 0.0 0.2 14.0 1.8 0.0 0.2 1.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 9.0 0.1 0.0 0.0 0.0 0.0 0.0 43.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.7 0.2 0.0 0.0 3.6 1.9 0.8 6.0 0.9 0.9 0.9 2.2 15.7 1.5 CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 39.8" "Cell line enhanced" "Detected in some" "RPMI-8226: 9.9;SH-SY5Y: 31.8;U-266/70: 13.2;U-266/84: 9.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 8.7" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.3" "Group enriched" "Detected in many" 18 "monocytes: 1.2;T-cells: 2.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024106, HPA048036" Approved Supported "Plasma membrane" "Plasma membrane" "HPA024106: AB_1854211, HPA048036: " "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "unprognostic (1.05e-1)" "unprognostic (4.11e-3)" "unprognostic (3.48e-3)" "unprognostic (5.81e-2)" "unprognostic (2.30e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (6.44e-2)" "unprognostic (5.34e-4)" "unprognostic (3.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" 0.8 0.0 2.1 1.4 1.8 0.0 0.8 0.8 8.7 0.8 5.9 0.8 0.8 0.8 1.4 0.8 6.6 0.3 0.8 0.8 2.5 1.8 0.8 0.8 1.5 0.8 0.8 1.1 4.3 8.7 0.2 0.8 0.8 0.8 3.8 2.2 39.8 13.7 2.5 0.8 0.7 1.2 3.3 0.8 1.0 4.8 1.7 0.8 1.3 1.3 0.8 1.6 7.1 0.8 0.0 0.0 0.0 1.2 0.0 2.3 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 3.4 0.3 2.3 1.6 0.0 2.2 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 5.5 0.5 0.8 0.0 0.0 2.8 5.0 0.0 0.7 9.9 0.4 0.5 0.0 31.8 0.0 0.1 0.1 1.1 0.0 0.0 1.3 0.5 0.1 0.3 13.2 9.4 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 1.2 0.7 0.0 0.5 0.4 0.0 0.0 2.3 0.7 0.0 0.0 0.7 0.0 0.5 0.2 2.1 1.8 0.8 8.7 2.5 1.8 0.8 1.1 0.8 0.8 CHRM4 ENSG00000180720 "Cholinergic receptor muscarinic 4" P08173 11 46385098-46386608 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.7;intestine: 8.0;lymphoid tissue: 17.2" "Cell line enhanced" "Detected in some" "RH-30: 4.9;SCLC-21H: 14.2;U-2 OS: 4.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "amygdala: 26.8;basal ganglia: 65.9;cerebral cortex: 30.5;hippocampal formation: 26.4;olfactory region: 36.4" "Group enriched" "Detected in many" 7 "amygdala: 5.5;basal ganglia: 15.3;cerebral cortex: 8.6;hippocampal formation: 7.6;olfactory region: 20.1" "CAB022444, HPA072083" Enhanced Uncertain "Nucleoplasm,Golgi apparatus" "Golgi apparatus" Nucleoplasm "CAB022444: , HPA072083: " "unprognostic (7.11e-2)" "unprognostic (3.79e-1)" "unprognostic (5.31e-2)" "unprognostic (7.38e-2)" "unprognostic (8.63e-3)" "unprognostic (1.38e-1)" "unprognostic (6.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (2.96e-3)" "unprognostic (4.08e-3)" "unprognostic (5.02e-2)" "unprognostic (3.83e-2)" "unprognostic (3.64e-1)" "unprognostic (1.71e-1)" "unprognostic (3.56e-1)" "unprognostic (5.08e-2)" 0.0 0.5 1.1 0.2 11.7 1.6 0.0 0.0 6.0 0.0 0.6 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 1.2 8.0 0.1 0.0 17.2 0.8 4.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.7 0.3 0.1 0.2 0.0 3.0 0.0 0.1 0.2 0.1 1.4 0.2 0.3 0.3 0.0 0.1 1.8 0.1 0.0 2.1 0.3 0.5 0.2 0.0 0.2 0.5 0.6 0.0 0.0 0.1 0.1 0.1 0.6 0.2 0.0 1.0 0.2 0.2 0.6 0.2 0.0 4.9 0.0 0.0 0.1 14.2 0.3 0.4 0.1 0.1 0.1 2.4 0.0 0.4 4.1 0.0 0.1 0.7 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 CHRM5 ENSG00000184984 "Cholinergic receptor muscarinic 5" P08912 15 33968720-34067457 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "brain: 22.8" "Group enriched" "Detected in some" 5 "BEWO: 5.4;HMC-1: 18.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "neutrophil: 4.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.8" "Region enhanced" "Detected in many" "hypothalamus: 15.4" "Low region specificity" "Detected in many" HPA013172 Uncertain "HPA013172: AB_1854212" "unprognostic (8.19e-2)" "unprognostic (2.13e-1)" "unprognostic (7.67e-2)" "unprognostic (4.32e-1)" "unprognostic (3.05e-3)" "unprognostic (2.77e-1)" "unprognostic (2.49e-2)" "unprognostic (2.79e-1)" "unprognostic (3.02e-1)" "unprognostic (1.27e-2)" "unprognostic (4.61e-4)" "unprognostic (7.95e-2)" "unprognostic (1.33e-6)" "unprognostic (1.42e-1)" "unprognostic (4.53e-2)" "unprognostic (1.38e-1)" "unprognostic (9.07e-2)" 0.3 0.5 1.2 0.9 15.7 1.3 2.1 0.8 6.9 0.3 0.4 5.1 0.0 1.1 0.5 0.8 0.5 0.3 0.6 0.3 6.8 4.4 0.6 0.9 0.4 1.0 5.8 4.5 0.5 1.0 0.1 0.5 4.8 17.8 0.6 0.3 0.0 0.5 0.1 0.7 1.8 1.8 0.2 22.8 0.7 0.6 5.2 0.0 0.0 2.3 0.0 0.3 0.4 0.3 0.3 0.9 4.8 0.3 0.2 0.3 0.0 0.1 0.2 0.8 0.3 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.5 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.2 0.7 0.3 0.2 0.0 0.5 18.8 0.4 0.0 0.2 0.1 0.0 0.6 1.2 0.1 0.2 0.2 2.2 0.2 0.3 0.1 0.3 0.2 0.0 0.4 0.3 0.3 0.3 0.7 0.2 0.2 1.1 0.2 0.2 0.2 0.2 0.1 0.9 0.3 0.4 0.1 0.2 0.3 1.5 0.3 0.2 0.3 0.1 0.3 0.2 0.2 0.2 0.1 0.3 0.1 0.2 4.8 0.2 0.1 0.9 0.2 0.0 1.2 15.7 0.8 6.9 6.8 4.4 5.8 4.5 17.8 0.0 CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339341 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.6" "Cell line enhanced" "Detected in some" "ASC diff: 7.8;ASC TERT1: 32.8;BJ hTERT+: 23.3;LHCN-M2: 7.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "intermediate monocyte: 11.9;plasmacytoid DC: 15.2" "Group enriched" "Detected in many" 31 "dendritic cells: 15.2;monocytes: 11.9;T-cells: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain "HPA047865: " "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (8.83e-3)" "unprognostic (7.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" 11.3 6.3 2.5 8.5 3.5 0.3 5.1 0.9 3.6 6.7 5.2 5.1 1.7 3.1 9.6 12.0 4.1 5.4 6.4 9.3 2.9 2.3 4.3 7.1 10.5 17.2 5.6 1.5 3.9 3.2 1.6 4.1 18.9 4.0 5.3 6.5 10.7 5.6 3.7 2.9 4.6 5.4 12.1 5.1 42.6 3.4 4.6 4.8 3.2 9.9 5.9 5.8 6.9 3.2 0.0 15.2 0.2 11.9 0.3 6.3 3.1 0.0 0.0 0.1 0.0 7.8 32.8 0.1 0.0 23.3 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.4 0.0 0.0 7.1 0.0 0.0 0.6 0.0 0.0 0.0 1.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 3.2 0.0 6.3 11.9 0.0 0.0 1.0 4.2 0.8 0.0 0.4 3.4 0.2 0.3 2.0 15.2 0.3 3.1 2.5 3.5 0.9 2.6 2.9 2.3 5.6 1.5 4.0 4.8 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.5" "Group enriched" "Detected in some" 7 "ASC diff: 39.4;HSkMC: 26.0" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 2.9;naive B-cell: 2.1" "Lineage enriched" "Detected in single" 6 "B-cells: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported "Plasma membrane,Actin filaments" "Plasma membrane" "Actin filaments" "HPA042256: , HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 19.4 6.4 18.0 5.2 15.8 1.5 14.9 13.8 30.5 3.9 5.5 0.8 0.8 2.3 3.1 4.7 3.7 5.5 3.6 1.4 17.6 7.7 0.9 0.7 6.4 6.5 2.3 14.7 4.1 1.8 1.3 18.3 5.2 4.2 1.5 5.1 0.0 4.3 4.0 1.7 2.4 4.2 5.8 3.2 2.3 2.3 2.7 2.8 0.0 2.6 0.0 9.9 2.7 3.1 2.9 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 39.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.8 1.3 0.0 2.6 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.0 3.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.7 3.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 18.0 15.8 13.8 21.4 17.6 7.7 2.3 14.7 4.2 2.8 CNR2 CB2 ENSG00000188822 "Cannabinoid receptor 2" P34972 1 23870526-23913362 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "blood: 19.2;lymphoid tissue: 31.1" "Cell line enhanced" "Detected in some" "Daudi: 4.9;HEL: 4.1;HMC-1: 18.9;U-698: 12.7" "Cancer enriched" "Detected in single" 6 "testis cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 19.2;eosinophil: 16.2;memory B-cell: 14.9;naive B-cell: 15.1;NK-cell: 8.7" "Group enriched" "Detected in many" 7 "B-cells: 15.1;granulocytes: 19.2;NK-cells: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB009719 Uncertain "CAB009719: AB_2082784" "unprognostic (9.45e-4)" "unprognostic (5.40e-3)" "unprognostic (8.50e-3)" "unprognostic (8.19e-3)" "unprognostic (3.55e-3)" "unprognostic (9.34e-6)" "unprognostic (5.58e-3)" "unprognostic (6.96e-3)" "unprognostic (1.74e-1)" "unprognostic (7.87e-2)" "unprognostic (1.53e-1)" "unprognostic (4.93e-2)" "unprognostic (1.04e-3)" "unprognostic (3.67e-1)" "unprognostic (1.80e-1)" "unprognostic (3.75e-2)" "unprognostic (4.91e-2)" 0.3 0.2 0.2 18.5 0.2 1.8 0.2 0.2 0.2 0.2 0.4 0.0 0.0 0.1 0.2 0.1 1.8 0.2 0.3 0.3 0.2 0.2 0.4 0.3 0.6 27.7 0.2 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.4 0.3 0.3 3.1 0.0 1.8 0.2 5.5 0.0 0.2 29.7 0.4 0.4 0.0 3.0 0.6 0.6 31.1 1.5 0.3 15.1 0.8 19.2 0.1 8.7 2.0 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.1 0.1 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 12.7 0.0 0.1 0.0 19.2 0.1 16.2 1.7 0.0 2.0 14.9 0.1 1.5 0.2 15.1 0.1 0.9 0.6 8.7 0.1 0.8 0.1 0.9 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 CRHR1 "CRF-R, CRF1, CRHR" ENSG00000120088 "Corticotropin releasing hormone receptor 1" P34998 17 45784280-45835828 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 23.2;pituitary gland: 16.5" "Group enriched" "Detected in some" 4 "RT4: 7.9;SH-SY5Y: 4.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" CAB025251 Enhanced "Intracellular and membrane" "CAB025251: " "unprognostic (4.59e-2)" "unprognostic (1.43e-2)" "unprognostic (2.59e-7)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (3.94e-2)" "unprognostic (2.48e-1)" "unprognostic (4.55e-4)" "unprognostic (1.65e-2)" "unprognostic (2.21e-1)" "unprognostic (3.33e-4)" "unprognostic (2.07e-5)" "unprognostic (3.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.59e-1)" 0.8 0.6 14.7 0.5 5.1 0.5 1.5 23.2 11.5 1.4 0.6 1.1 0.0 0.8 2.7 1.1 0.5 1.6 0.7 0.5 3.2 2.2 0.6 0.5 0.6 0.5 1.8 5.2 0.6 0.5 0.6 16.5 0.6 2.9 1.3 0.6 1.9 1.2 2.5 0.6 1.4 1.0 1.2 1.0 0.5 0.5 1.0 2.8 0.0 0.9 0.0 0.5 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 1.6 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 5.1 23.2 11.5 3.2 2.2 1.8 5.2 2.9 2.8 CX3CR1 "CCRL1, CMKBRL1, CMKDR1, GPR13, V28" ENSG00000168329 "C-X3-C motif chemokine receptor 1" P49238 3 39263494-39281735 "Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood: 69.2;brain: 51.6" "Cell line enriched" "Detected in some" 20 "RPMI-8226: 112.1" "Cancer enhanced" "Detected in many" "glioma: 21.1" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 69.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032478, HPA046587" Approved "CAB032478: AB_638830, HPA046587: " "unprognostic (2.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.65e-1)" "unprognostic (2.42e-2)" "unprognostic (6.52e-2)" "unprognostic (3.01e-3)" "unprognostic (2.64e-1)" "unprognostic (1.16e-2)" "unprognostic (3.98e-2)" "unprognostic (1.57e-3)" "unprognostic (1.13e-2)" "unprognostic (1.04e-1)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (8.59e-2)" "unprognostic (7.71e-3)" "unprognostic (1.12e-1)" 2.3 3.8 14.9 6.0 17.3 0.9 4.8 2.5 34.1 2.7 1.2 51.6 0.0 1.2 2.7 4.2 1.4 5.9 2.5 2.2 12.4 11.9 2.5 1.9 9.0 1.8 21.8 7.4 1.8 1.8 5.2 2.5 4.3 21.8 3.7 1.2 3.5 6.4 7.0 5.2 2.4 1.2 3.3 33.5 10.3 1.5 1.8 16.3 0.8 2.4 0.7 4.7 2.8 1.3 0.1 15.7 3.5 69.2 6.5 46.5 29.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 112.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.5 0.0 1.2 15.9 0.2 46.5 43.3 0.5 0.1 10.4 25.2 15.7 0.1 3.7 22.7 3.5 6.5 69.2 1.1 0.2 29.8 14.9 17.3 2.5 19.9 12.4 11.9 21.8 7.4 21.8 16.3 CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162845-218166995 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "blood: 144.6" "Cell line enriched" "Detected in single" 26 "HMC-1: 11.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in some" 16 "neutrophil: 144.6" "Lineage enriched" "Detected in many" 59 "granulocytes: 144.6" "Not detected" "Not detected" HPA031991 Uncertain "HPA031991: " "unprognostic (2.80e-1)" "unprognostic (2.91e-2)" "unprognostic (3.53e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.14e-2)" "unprognostic (3.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" 11.5 0.4 0.8 21.1 0.7 7.3 0.6 0.9 2.6 0.6 0.6 0.2 0.0 0.0 0.5 0.1 1.3 2.8 3.6 3.8 0.9 0.6 0.7 2.9 20.3 33.4 5.9 0.0 1.7 1.2 0.0 0.8 2.1 2.3 0.9 0.1 1.4 0.6 0.0 1.0 0.5 0.6 1.4 3.4 33.7 1.0 1.4 0.7 0.1 0.9 0.6 0.4 4.5 4.1 0.0 0.0 144.6 0.2 0.1 2.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.2 0.2 2.4 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.9 144.6 0.1 0.2 0.0 0.0 0.7 0.8 0.7 0.9 2.6 0.9 0.6 5.9 0.0 2.3 0.7 CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137253 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "blood: 216.1" "Group enriched" "Detected in some" 11 "BEWO: 12.1;HL-60: 6.7;HMC-1: 14.1;THP-1: 12.8;U-937: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 59 "neutrophil: 216.1" "Lineage enriched" "Detected in many" 109 "granulocytes: 216.1" "Low region specificity" "Detected in single" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" 9.3 0.9 1.3 25.6 1.5 4.0 0.6 1.2 1.3 5.2 0.6 0.5 2.5 0.0 0.8 1.1 18.1 3.3 5.2 4.3 1.5 0.6 0.7 4.6 16.7 40.5 6.6 0.0 1.2 1.7 0.0 0.7 4.5 1.7 1.9 0.3 1.8 3.3 2.6 0.6 3.0 0.7 1.4 4.1 30.6 1.0 1.1 0.7 0.6 0.6 4.8 10.1 5.4 6.4 0.0 1.6 216.1 1.9 0.4 1.9 1.0 0.0 0.0 0.1 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.7 14.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 1.0 0.2 0.0 0.3 0.0 1.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 12.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 12.6 0.0 3.6 1.9 3.2 1.9 0.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.7 216.1 0.4 0.2 1.6 0.0 1.0 1.3 1.5 1.2 1.3 1.5 0.6 6.6 0.0 1.7 0.7 CXCR3 "CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR" ENSG00000186810 "C-X-C motif chemokine receptor 3" P49682 X 71615916-71618517 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 61.7;lymphoid tissue: 24.5" "Cell line enriched" "Detected in some" 15 "RPMI-8226: 31.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 61.7" "Group enriched" "Detected in many" 4 "dendritic cells: 61.7;NK-cells: 38.1;T-cells: 26.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045942 Enhanced "HPA045942: " "unprognostic (4.84e-3)" "unprognostic (3.05e-3)" "unprognostic (1.61e-1)" "prognostic favourable (3.44e-6)" "unprognostic (3.93e-2)" "prognostic favourable (3.35e-4)" "unprognostic (1.01e-2)" "unprognostic (5.24e-2)" "prognostic favourable (2.90e-4)" "unprognostic (6.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "prognostic unfavourable (1.67e-6)" "unprognostic (4.67e-2)" "unprognostic (2.18e-1)" "unprognostic (2.91e-2)" "unprognostic (5.76e-2)" 0.9 0.9 0.4 9.0 0.4 6.0 0.6 0.3 0.3 1.9 2.4 0.4 0.5 5.4 3.3 1.4 1.3 1.1 2.6 2.4 0.3 0.4 1.9 0.8 4.5 19.0 0.4 0.1 1.6 0.8 0.0 0.6 0.7 0.5 2.9 0.8 1.5 3.9 1.0 0.4 0.5 9.1 0.3 0.7 13.9 2.6 0.6 0.0 14.0 1.9 1.7 24.5 1.7 1.8 9.8 61.7 0.4 0.0 38.1 26.6 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 17.3 0.0 8.9 9.8 19.6 26.6 1.6 1.8 1.2 11.1 0.4 38.1 0.0 61.7 17.8 6.3 0.4 0.4 0.3 0.3 0.3 0.4 0.4 0.1 0.5 0.0 CXCR5 "BLR1, CD185, MDR15" ENSG00000160683 "C-X-C motif chemokine receptor 5" P32302 11 118883766-118897799 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "B-cell activation" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 35.5;lymphoid tissue: 45.6" "Group enriched" "Detected in some" 10 "Daudi: 10.3;U-698: 36.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebellum: 4.0" "Group enriched" "Detected in some" 8 "memory B-cell: 24.2;naive B-cell: 35.5" "Lineage enriched" "Detected in many" 9 "B-cells: 35.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB026149, HPA042432" Enhanced "CAB026149: , HPA042432: " "unprognostic (8.51e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-1)" "unprognostic (4.02e-5)" "unprognostic (2.08e-2)" "unprognostic (3.23e-3)" "unprognostic (1.19e-2)" "unprognostic (3.66e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-5)" "unprognostic (4.21e-1)" "unprognostic (2.03e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" 0.4 0.8 0.6 31.8 0.6 7.3 0.1 4.0 0.9 0.1 3.6 0.2 0.1 0.1 0.2 0.1 2.6 0.0 0.5 0.9 0.7 0.5 0.8 1.0 0.9 31.5 0.3 0.1 0.3 0.5 0.0 0.9 0.1 0.2 2.9 0.3 0.3 3.6 0.1 1.3 0.9 8.6 0.1 0.3 45.6 1.3 0.1 0.1 1.9 0.7 1.3 41.8 3.9 0.9 35.5 0.0 0.0 0.0 0.0 3.9 1.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 10.3 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.4 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.1 0.5 0.0 0.2 0.4 0.0 0.0 0.2 0.0 36.2 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.3 24.2 3.9 1.0 0.0 35.5 0.4 0.3 0.0 0.0 0.0 0.0 0.5 1.9 0.6 0.6 4.0 0.9 0.7 0.5 0.3 0.1 0.2 0.1 CYSLTR1 "CysLT(1), CysLT1, CYSLT1R" ENSG00000173198 "Cysteinyl leukotriene receptor 1" Q9Y271 X 78271464-78327691 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 33.9;esophagus: 24.6" "Cell line enhanced" "Detected in some" "HL-60: 11.3;Karpas-707: 7.4;NB-4: 15.9;RPMI-8226: 24.1;THP-1: 14.9;U-937: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 33.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010546 Approved "HPA010546: AB_1078268" "unprognostic (9.48e-2)" "unprognostic (6.01e-5)" "unprognostic (4.72e-3)" "unprognostic (3.04e-1)" "unprognostic (6.30e-2)" "unprognostic (2.80e-3)" "unprognostic (2.52e-1)" "unprognostic (8.19e-2)" "unprognostic (1.19e-1)" "unprognostic (2.53e-2)" "unprognostic (4.55e-1)" "unprognostic (2.43e-1)" "unprognostic (4.41e-4)" "unprognostic (5.82e-2)" "unprognostic (3.56e-2)" "unprognostic (9.87e-2)" "unprognostic (8.94e-2)" 7.3 2.0 1.7 7.8 1.7 2.8 5.4 0.8 2.2 3.0 3.3 1.7 2.9 2.2 2.3 4.4 24.6 2.3 5.6 3.1 2.3 1.9 4.8 2.7 6.9 19.5 3.8 0.8 1.7 2.0 1.7 1.5 3.3 2.9 3.7 4.8 3.1 5.4 0.8 1.7 3.1 7.1 4.2 5.1 22.8 5.2 2.3 4.0 4.7 4.5 4.8 11.3 9.8 3.5 8.1 7.4 33.9 11.9 4.1 3.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 11.3 4.7 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 15.9 0.0 0.0 3.2 0.0 24.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 16.4 0.0 5.8 6.3 33.9 0.0 10.9 0.0 8.1 2.4 0.1 4.8 5.8 3.7 0.0 18.4 4.1 11.9 7.4 0.5 2.8 1.7 1.7 0.8 2.2 2.3 1.9 3.8 0.8 2.9 4.0 CYSLTR2 "CysLT(2), CYSLT2R" ENSG00000152207 "Cysteinyl leukotriene receptor 2" Q9NS75 13 48653711-48711226 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 37.2;ductus deferens: 25.1;placenta: 22.6;seminal vesicle: 22.4" "Cell line enriched" "Detected in single" 77 "HDLM-2: 43.7" "Group enriched" "Detected in many" 6 "melanoma: 1.8;renal cancer: 6.6;thyroid cancer: 7.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 12 "eosinophil: 37.2" "Lineage enriched" "Detected in many" 12 "granulocytes: 37.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA046528 Uncertain "HPA046528: " "unprognostic (9.83e-3)" "unprognostic (2.72e-3)" "unprognostic (1.05e-2)" "unprognostic (6.81e-2)" "unprognostic (2.94e-2)" "unprognostic (3.11e-2)" "unprognostic (1.11e-1)" "unprognostic (7.41e-3)" "unprognostic (8.33e-2)" "unprognostic (1.83e-1)" "unprognostic (5.44e-2)" "unprognostic (5.93e-2)" "unprognostic (1.88e-3)" "unprognostic (3.79e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-2)" "unprognostic (1.18e-2)" 2.0 11.4 3.4 3.9 4.2 0.7 1.0 1.6 8.0 0.9 1.0 1.1 25.1 2.1 1.3 1.7 0.7 3.4 1.6 11.5 4.1 3.4 1.8 1.0 1.5 4.4 3.3 1.5 5.4 0.5 0.7 2.3 22.6 3.7 3.4 1.1 2.9 0.7 22.4 0.5 1.3 2.5 0.7 2.3 6.9 1.1 1.0 2.9 1.0 1.1 0.5 1.5 1.0 1.2 0.0 0.9 37.2 3.2 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 1.0 37.2 0.2 3.2 0.0 0.0 0.4 0.0 0.9 0.0 0.5 0.1 0.1 0.4 2.0 0.0 0.3 0.4 3.4 4.2 1.6 8.0 4.1 3.4 3.3 1.5 3.7 2.9 DRD1 ENSG00000184845 "Dopamine receptor D1" P21728 5 175440039-175444208 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 34.5" "Cell line enriched" "Detected in some" 5 "RT4: 23.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "basal ganglia: 34.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 9 "basal ganglia: 147.4" "Region enriched" "Detected in many" 13 "basal ganglia: 95.6" HPA013393 Supported "HPA013393: AB_1847833" "unprognostic (2.74e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-3)" "unprognostic (1.28e-1)" "unprognostic (1.15e-6)" "unprognostic (6.69e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (8.60e-4)" "unprognostic (5.86e-2)" "unprognostic (5.43e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" 0.7 1.5 1.9 0.2 34.5 0.0 0.1 0.1 12.0 0.7 0.7 0.4 0.0 0.5 0.4 0.7 0.7 0.6 1.1 0.3 1.0 0.6 0.7 2.6 1.8 0.1 0.5 1.6 0.3 0.0 0.0 0.1 2.5 0.3 2.7 0.9 2.1 0.1 1.2 0.1 0.1 0.3 0.4 0.1 0.4 0.4 0.1 6.8 0.1 0.1 0.0 0.4 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 34.5 0.1 5.3 1.0 0.6 0.5 1.6 0.3 6.8 DRD2 ENSG00000149295 "Dopamine receptor D2" P14416 11 113409615-113475691 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adrenal gland: 17.3;brain: 52.0;pituitary gland: 51.6" "Cell line enriched" "Detected in some" 9 "SCLC-21H: 44.2" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "basal ganglia: 52.0" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 10 "basal ganglia: 183.8" "Group enriched" "Detected in many" 9 "basal ganglia: 126.7;midbrain: 41.7" "HPA015139, HPA015691" Supported Supported "HPA015139: , HPA015691: AB_1847834" "unprognostic (8.49e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-4)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (5.89e-2)" "unprognostic (4.40e-2)" "unprognostic (8.33e-4)" "unprognostic (1.10e-1)" "unprognostic (6.65e-3)" "unprognostic (2.29e-1)" "unprognostic (1.71e-1)" "unprognostic (4.82e-2)" "unprognostic (8.49e-3)" 0.6 17.3 0.9 0.5 52.0 0.2 2.1 0.2 3.3 1.3 0.6 1.5 0.0 0.3 2.3 0.4 0.9 2.1 0.6 0.5 0.3 4.1 0.3 0.2 0.6 0.2 9.9 0.2 0.3 0.4 0.3 51.6 0.2 2.4 1.5 0.9 3.9 5.1 1.7 1.7 0.3 0.5 3.2 0.2 0.2 0.5 1.6 9.5 0.0 0.2 0.0 0.3 0.3 0.3 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.5 0.0 0.0 4.7 0.0 0.0 0.0 44.2 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.9 52.0 0.2 3.3 0.3 4.1 9.9 0.2 2.4 9.5 DRD5 "DRD1B, DRD1L2" ENSG00000169676 "Dopamine receptor D5" P21918 4 9781680-9784009 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Dystonia, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 8.4;lymphoid tissue: 3.5;stomach 1: 10.9" "Cell line enhanced" "Detected in some" "REH: 3.6;THP-1: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA048930 Supported "HPA048930: " "unprognostic (2.03e-2)" "unprognostic (2.63e-1)" "unprognostic (9.73e-2)" "unprognostic (4.27e-2)" "unprognostic (4.44e-3)" "unprognostic (1.98e-2)" "unprognostic (1.32e-4)" "unprognostic (5.09e-4)" "unprognostic (6.51e-2)" "unprognostic (1.46e-1)" "unprognostic (7.36e-3)" 0.2 0.2 2.8 3.5 4.1 0.1 0.2 0.0 8.4 0.1 0.9 0.0 0.0 0.9 0.1 0.1 0.3 0.3 0.1 0.1 3.2 3.2 0.2 0.1 0.4 0.2 1.9 0.8 0.1 0.2 0.1 1.0 0.1 7.4 0.6 0.2 0.4 0.2 0.2 0.1 0.2 0.2 0.2 0.6 0.1 10.9 1.3 1.0 0.0 0.2 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 3.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 2.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.1 0.0 8.4 3.2 3.2 1.9 0.8 7.4 1.0 EDNRA ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 62.6;seminal vesicle: 52.3" "Cell line enhanced" "Detected in some" "ASC diff: 7.2;ASC TERT1: 14.2;HHSteC: 7.3;LHCN-M2: 16.8;SH-SY5Y: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Uncertain "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavourable (1.50e-7)" "prognostic unfavourable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" 7.6 2.6 1.3 1.4 1.8 0.0 7.2 0.6 2.4 62.6 2.6 1.0 21.7 1.5 37.3 14.2 4.7 13.3 7.3 15.1 1.3 1.3 3.1 1.4 12.7 2.0 1.8 1.0 23.5 0.9 1.9 2.2 5.9 2.7 21.5 1.5 10.3 4.1 52.3 4.8 3.2 1.8 19.4 1.6 11.5 4.4 9.1 1.4 2.9 5.0 6.0 2.6 14.7 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 4.1 0.0 7.2 14.2 0.0 2.1 2.8 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.3 0.5 0.2 0.0 1.5 0.0 2.4 0.0 7.3 0.0 0.0 5.5 0.4 0.4 0.0 0.0 0.0 1.1 16.8 0.2 0.0 0.1 1.2 0.8 0.0 0.7 0.1 1.1 0.8 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.6 0.0 0.0 1.1 0.3 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.8 0.6 2.4 1.3 1.3 1.8 1.0 2.7 1.4 EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease mutation, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 67.5" "Cell line enhanced" "Detected in some" "AF22: 24.6;ASC diff: 18.7;SK-MEL-30: 22.6;U-266/70: 14.8;WM-115: 47.1" "Group enriched" "Detected in all" 7 "glioma: 41.1;melanoma: 127.7;renal cancer: 28.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "classical monocyte: 2.0;intermediate monocyte: 2.1" "Lineage enriched" "Detected in single" 21 "monocytes: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "CAB017842: , HPA027546: " "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favourable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" 25.4 23.2 22.2 10.3 29.8 0.8 23.1 10.3 30.7 8.1 7.2 13.6 2.3 10.9 7.7 3.6 4.9 6.0 8.5 23.7 16.7 16.4 22.3 26.5 28.4 15.6 24.2 8.1 4.9 6.4 7.7 6.3 67.5 33.2 14.9 7.7 51.0 13.4 4.4 6.7 5.1 11.9 7.4 33.4 16.0 5.8 3.1 12.4 0.0 17.6 2.0 2.9 10.9 8.2 0.0 0.0 0.0 2.1 0.0 0.0 0.4 1.9 0.0 24.6 0.0 18.7 0.7 0.3 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 22.6 0.0 0.1 0.1 0.2 0.0 0.0 0.1 14.8 8.3 0.0 0.4 0.0 47.1 0.0 2.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22.2 29.8 10.3 11.9 16.7 16.4 24.2 8.1 33.2 12.4 F2R "CF2R, PAR-1, PAR1, TR" ENSG00000181104 "Coagulation factor II thrombin receptor" P25116 5 76716043-76735781 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 67.5" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 71.1;WM-115: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "gdT-cell: 17.6" "Lineage enriched" "Detected in many" 4 "T-cells: 17.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008973, CAB012962" Approved "CAB008973: , CAB012962: AB_2533198" "unprognostic (3.03e-1)" "unprognostic (7.76e-2)" "unprognostic (5.55e-2)" "unprognostic (7.76e-2)" "unprognostic (7.14e-2)" "unprognostic (3.46e-1)" "unprognostic (2.51e-1)" "unprognostic (3.75e-2)" "unprognostic (5.37e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.22e-1)" "prognostic unfavourable (2.21e-7)" "unprognostic (2.72e-3)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (6.74e-3)" 12.3 11.2 1.5 7.5 2.2 1.1 8.9 0.8 3.5 11.7 14.0 3.3 20.1 5.9 17.6 8.6 9.3 3.5 20.8 19.2 1.4 1.7 19.5 22.6 24.4 10.4 1.5 1.8 6.2 4.0 1.6 4.7 32.0 2.5 9.6 5.1 9.6 26.4 14.0 7.2 23.7 15.5 8.4 3.5 67.5 4.5 16.6 1.4 4.0 9.1 11.4 13.5 10.7 4.7 0.4 0.2 0.8 0.3 4.2 17.6 6.4 1.0 3.3 10.4 1.7 19.8 34.6 0.5 5.8 19.9 3.8 13.9 0.7 9.1 0.0 9.9 2.4 2.5 4.4 3.5 7.3 0.8 3.7 22.7 0.7 2.8 29.9 0.1 0.9 19.5 11.8 7.3 2.0 71.1 4.2 4.3 7.8 0.4 1.7 0.0 3.3 18.2 3.2 6.2 0.8 18.0 0.1 1.2 5.6 1.7 0.0 8.5 0.1 0.2 32.5 24.2 5.4 0.2 10.7 11.6 3.4 0.0 6.4 0.4 67.0 0.5 0.2 0.3 17.6 0.3 4.4 0.4 4.1 12.1 0.0 0.1 0.7 9.1 0.8 4.2 0.1 0.2 0.4 6.4 1.5 2.2 0.8 2.1 1.4 1.7 1.5 1.8 2.5 1.4 F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 64.1" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 23.6;PC-3: 34.4;RPTEC TERT1: 57.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "pons and medulla: 7.8" "Cell type enriched" "Detected in many" 4 "neutrophil: 24.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" "Plasma membrane" "CAB012989: AB_2533199, HPA014091: " "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favourable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavourable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavourable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favourable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" 0.6 1.1 1.0 7.2 1.4 0.1 2.9 0.4 0.8 2.4 34.0 1.1 25.3 17.4 1.0 2.2 6.4 2.9 13.6 3.6 1.1 0.9 28.9 7.4 2.8 3.7 0.8 0.4 1.2 16.6 1.3 3.2 2.8 7.8 6.0 21.4 1.1 7.1 23.7 0.3 24.8 64.1 0.7 1.5 3.5 16.8 0.8 0.5 0.6 9.6 5.8 3.1 5.3 3.9 0.3 2.7 24.9 5.7 0.3 2.3 2.0 8.6 14.3 1.2 0.0 0.4 1.1 9.2 0.4 4.7 0.2 0.7 12.3 22.4 0.0 19.3 1.0 14.9 7.5 6.6 0.4 0.0 7.0 0.2 0.3 8.7 3.1 0.0 0.0 1.6 19.0 2.2 14.2 23.6 0.1 0.0 0.0 4.7 1.0 0.0 1.5 34.4 0.0 0.0 0.2 57.0 16.1 0.6 0.1 3.4 3.4 0.0 1.4 0.0 15.6 0.0 9.0 0.0 0.0 1.3 0.2 0.0 5.1 0.0 0.4 4.6 5.7 1.0 0.3 1.9 1.2 0.3 2.3 1.2 2.7 0.1 2.2 1.3 24.9 0.3 0.3 0.3 0.6 2.0 1.0 1.4 0.4 0.8 1.1 0.9 0.8 0.4 7.8 0.5 F2RL3 PAR4 ENSG00000127533 "F2R like thrombin or trypsin receptor 3" Q96RI0 19 16888860-16892606 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 69.4;breast: 30.7;lung: 33.0" "Group enriched" "Detected in some" 7 "HEL: 24.3;HMC-1: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031401, HPA042340" Enhanced "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA031401: , HPA042340: " "unprognostic (6.17e-2)" "unprognostic (1.08e-1)" "unprognostic (2.64e-2)" "unprognostic (3.83e-1)" "unprognostic (3.27e-1)" "unprognostic (8.31e-3)" "unprognostic (2.97e-1)" "unprognostic (3.28e-2)" "unprognostic (6.52e-2)" "unprognostic (2.60e-1)" "unprognostic (6.30e-2)" "unprognostic (3.00e-3)" "prognostic favourable (6.25e-4)" "unprognostic (2.37e-2)" "unprognostic (1.43e-1)" "unprognostic (3.53e-1)" "unprognostic (2.11e-2)" 69.4 3.3 0.2 2.6 0.4 1.3 30.7 0.2 0.6 1.3 16.9 0.4 0.5 1.9 1.3 1.9 4.3 1.0 4.5 9.7 0.5 0.2 5.0 0.8 33.0 2.6 0.2 0.3 3.9 12.3 0.5 2.3 1.1 1.4 1.4 1.5 1.3 1.0 0.8 6.5 2.2 4.4 1.1 0.2 3.0 5.4 2.5 0.2 0.3 27.1 2.3 1.5 3.4 1.9 5.3 4.3 5.8 2.5 3.9 3.3 3.2 0.2 0.2 0.7 0.3 0.1 0.2 0.7 0.4 0.0 0.2 0.1 0.4 0.7 0.5 0.5 0.2 0.6 0.1 0.2 0.2 0.3 0.3 24.3 0.9 0.4 0.2 0.3 9.8 0.0 0.1 0.3 0.2 0.8 1.9 1.0 0.1 0.3 0.3 2.4 0.3 0.2 0.2 0.2 0.7 0.2 0.5 0.4 0.2 0.2 0.1 0.1 0.5 1.6 0.9 0.5 0.5 0.3 0.3 0.5 0.3 0.5 0.2 0.4 0.4 5.8 2.5 1.6 2.2 1.4 2.1 3.9 2.4 1.9 0.8 5.3 3.3 3.1 5.3 3.9 1.8 4.3 1.7 3.2 0.2 0.4 0.2 0.6 0.5 0.2 0.2 0.3 1.4 0.2 FFAR2 "FFA2R, GPR43" ENSG00000126262 "Free fatty acid receptor 2" O15552 19 35443907-35451767 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 60.2;lymphoid tissue: 22.9" "Cell line enhanced" "Detected in some" "HMC-1: 8.8;SK-BR-3: 2.5;THP-1: 2.8;U-937: 3.5" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Region enhanced" "Detected in many" "midbrain: 7.0" "Group enriched" "Detected in some" 27 "eosinophil: 18.9;neutrophil: 60.2" "Lineage enriched" "Detected in many" 42 "granulocytes: 60.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA023985 Approved "HPA023985: AB_1849302" "unprognostic (7.75e-3)" "unprognostic (5.65e-2)" "unprognostic (4.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (6.16e-2)" "unprognostic (2.04e-1)" "unprognostic (1.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.30e-2)" "unprognostic (4.60e-2)" "unprognostic (5.17e-4)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-2)" 4.3 0.3 1.1 16.5 0.8 16.7 9.2 0.3 1.8 0.4 1.6 0.2 0.0 3.0 0.5 0.9 1.5 1.3 1.2 1.4 0.9 0.3 0.5 1.6 8.9 15.2 7.0 0.5 0.8 0.4 0.3 0.3 1.9 1.3 1.1 0.5 0.8 0.7 0.0 0.3 0.8 4.1 1.0 1.2 22.9 1.0 0.9 0.3 0.8 0.6 1.2 0.7 2.3 4.6 0.0 0.2 60.2 1.4 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.3 0.1 8.8 0.2 0.3 0.1 0.0 0.0 0.2 0.4 0.0 1.8 0.0 1.3 0.1 0.1 0.1 0.0 0.0 0.0 0.2 1.7 0.1 0.0 2.5 0.1 0.3 2.8 0.0 0.2 0.1 0.1 0.2 0.2 0.1 0.1 0.0 3.5 0.0 0.6 0.4 18.9 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 60.2 0.0 1.4 0.0 0.0 0.1 1.1 0.8 0.3 1.8 0.9 0.3 7.0 0.5 1.3 0.3 FFAR3 "FFA3R, GPR41" ENSG00000185897 "Free fatty acid receptor 3" O14843 19 35358460-35360485 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.5;blood: 5.6;lymphoid tissue: 6.1" "Group enriched" "Detected in some" 5 "ASC diff: 1.1;HHSteC: 3.8;HSkMC: 3.3;U-937: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "eosinophil: 4.7;neutrophil: 5.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.6" HPA044681 Uncertain "HPA044681: " "unprognostic (1.15e-1)" "unprognostic (5.16e-3)" "unprognostic (1.45e-1)" "unprognostic (3.08e-2)" "unprognostic (1.03e-3)" "unprognostic (2.21e-2)" "unprognostic (4.46e-2)" "unprognostic (1.34e-1)" "unprognostic (1.92e-4)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-3)" "unprognostic (2.18e-2)" "unprognostic (3.41e-1)" "unprognostic (3.22e-2)" 6.5 0.0 0.1 6.1 0.3 1.7 3.8 0.0 0.2 0.0 2.1 0.7 0.0 0.0 0.0 0.5 1.1 0.2 0.4 0.2 0.0 0.5 0.6 0.4 0.5 0.3 1.0 0.4 0.5 0.9 0.2 0.1 0.0 0.0 0.0 0.0 0.9 3.7 1.5 2.4 1.3 0.0 0.9 0.0 0.7 0.0 0.0 0.1 5.6 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.4 0.0 0.1 4.7 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.3 0.0 0.0 0.2 FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 15.8;lung: 11.7;pituitary gland: 39.2" "Cell line enhanced" "Detected in some" "A549: 3.3;CACO-2: 2.7;HaCaT: 5.5;NB-4: 6.1" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042563 Uncertain "Plasma membrane" "Plasma membrane" "HPA042563: AB_10794762" "unprognostic (1.96e-1)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (4.98e-4)" "unprognostic (1.41e-3)" "unprognostic (1.20e-2)" "unprognostic (2.34e-2)" "unprognostic (7.87e-2)" "unprognostic (9.51e-2)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (5.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" 5.2 0.6 1.8 2.8 1.7 0.2 1.9 0.1 2.6 0.2 11.3 1.1 0.0 0.7 0.1 0.1 0.4 1.4 2.6 1.2 0.9 1.6 0.3 0.6 11.7 1.3 0.6 1.0 0.3 1.1 0.1 39.2 0.4 0.8 0.2 15.8 0.3 0.9 0.1 0.5 1.3 1.0 0.3 2.6 0.2 0.7 2.0 0.9 0.7 0.2 0.0 0.6 0.3 0.2 0.5 3.4 1.3 3.0 0.7 0.3 0.8 0.1 3.3 0.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 2.7 0.8 0.2 0.5 0.0 5.5 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 6.1 0.3 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.1 0.1 0.1 0.0 1.1 0.2 0.3 0.1 0.2 0.3 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.9 3.0 0.2 0.3 0.6 0.2 0.4 0.2 0.2 3.4 0.5 0.2 0.3 1.3 0.7 0.4 0.4 0.1 0.8 1.8 1.7 0.1 2.6 0.9 1.6 0.6 1.0 0.8 0.9 FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 213.3;lymphoid tissue: 64.4" "Cell line enriched" "Detected in some" 5 "U-87 MG: 34.2" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "neutrophil: 213.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 213.3" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: , HPA061744: " "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavourable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" 22.6 3.7 5.2 52.2 12.4 54.5 2.9 1.1 6.3 2.6 2.4 5.9 0.0 1.1 2.3 2.3 3.3 8.4 9.6 11.2 15.7 4.3 6.0 7.5 28.8 58.4 15.5 0.8 1.9 3.5 0.8 2.3 13.0 9.7 1.8 1.2 2.4 2.4 0.9 3.2 1.1 2.2 12.8 14.3 64.4 3.2 2.9 10.1 0.9 2.7 0.7 3.2 7.9 4.6 0.0 8.9 213.3 36.3 0.0 0.0 16.9 0.3 0.5 0.2 0.3 0.4 1.1 0.3 0.2 0.0 0.3 1.0 0.2 0.3 0.6 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.6 2.7 0.2 0.4 2.4 0.1 0.8 0.8 0.0 0.1 0.3 6.9 0.5 0.1 0.2 0.2 0.4 0.2 0.4 0.0 0.6 0.3 0.1 0.2 0.4 0.0 0.3 0.6 0.6 0.5 1.1 0.2 0.0 1.6 0.1 0.0 0.3 34.2 0.8 0.1 13.0 36.3 10.0 0.0 15.9 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 213.3 0.0 9.5 0.3 0.0 16.9 5.2 12.4 1.1 6.3 15.7 4.3 15.5 0.8 9.7 10.1 FPR2 "ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R" ENSG00000171049 "Formyl peptide receptor 2" P25090 19 51752026-51770526 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 128.2;lymphoid tissue: 32.2" "Cell line enriched" "Detected in some" 18 "U-937: 25.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 10 "neutrophil: 128.2" "Lineage enriched" "Detected in many" 10 "granulocytes: 128.2" HPA029154 Approved "HPA029154: AB_10602133" "unprognostic (3.11e-1)" "unprognostic (5.20e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (3.90e-4)" "unprognostic (3.41e-5)" "unprognostic (1.08e-2)" "unprognostic (4.69e-2)" "unprognostic (5.10e-2)" "unprognostic (1.90e-1)" 7.9 1.1 0.6 30.7 2.1 8.7 0.8 0.4 1.9 0.6 0.8 0.8 0.0 0.4 0.6 0.2 1.0 2.6 3.3 5.0 1.9 0.6 1.3 2.4 17.3 32.2 2.8 0.0 1.6 1.1 0.0 1.1 4.4 2.3 0.6 0.1 1.1 1.0 0.0 1.1 0.4 1.1 3.3 3.0 29.1 1.2 2.5 1.6 0.8 1.0 0.9 0.3 4.4 2.2 0.0 1.7 128.2 12.7 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.7 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.8 25.4 0.0 0.4 12.7 0.6 0.0 11.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 128.2 0.0 7.5 0.3 0.0 3.9 0.6 2.1 0.4 1.9 1.9 0.6 2.8 0.0 2.3 1.6 FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264364-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 61.2" "Cell line enhanced" "Detected in many" "AF22: 16.3;HSkMC: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 4.2;non-classical monocyte: 5.4" "Lineage enriched" "Detected in many" 4 "monocytes: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favourable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" 5.8 4.6 2.6 4.9 3.5 0.9 10.7 8.2 2.8 17.6 8.5 4.1 9.3 4.9 10.1 9.9 7.8 6.1 11.0 12.3 6.1 1.8 15.3 3.9 10.5 1.4 2.0 3.2 15.0 7.9 2.5 4.6 10.0 5.7 12.3 3.7 11.1 9.2 17.5 3.1 10.7 8.3 7.2 4.6 3.4 4.5 4.4 3.5 1.4 61.2 6.5 2.9 10.4 13.9 0.1 1.3 0.2 5.4 0.0 0.0 0.4 0.5 1.6 16.3 1.7 13.3 11.5 3.0 5.9 3.8 2.2 1.5 0.7 2.8 0.0 1.4 3.8 3.0 2.5 1.3 1.4 0.0 3.2 0.1 3.1 0.8 0.9 2.6 0.7 21.8 2.3 5.0 1.6 0.5 0.9 2.3 6.3 3.9 0.4 0.7 4.2 2.7 3.2 10.0 0.2 3.5 7.6 2.2 4.3 4.5 3.7 0.9 1.9 2.4 2.4 9.3 7.0 9.8 2.4 2.2 1.5 0.2 10.0 2.2 10.7 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 5.4 0.1 0.0 0.4 2.6 3.5 8.2 2.8 6.1 1.8 2.0 3.2 5.7 3.5 FZD10 CD350 ENSG00000111432 "Frizzled class receptor 10" Q9ULW2 12 130162459-130165740 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.9;lymphoid tissue: 18.6" "Group enriched" "Detected in some" 4 "AF22: 8.4;BEWO: 9.7;hTCEpi: 5.6;RPTEC TERT1: 2.9;RT4: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "thalamus: 7.6" "Low region specificity" "Detected in many" "HPA014484, HPA014485" Uncertain Approved Nucleoplasm Nucleoplasm "HPA014484: AB_1849132, HPA014485: AB_1849134" "unprognostic (2.41e-3)" "unprognostic (3.29e-1)" "unprognostic (4.74e-2)" "prognostic favourable (5.05e-7)" "unprognostic (2.81e-2)" "unprognostic (4.63e-2)" "unprognostic (8.62e-3)" "unprognostic (6.33e-2)" "unprognostic (5.41e-2)" "unprognostic (3.77e-2)" "unprognostic (2.70e-1)" "unprognostic (2.24e-3)" "unprognostic (2.66e-9)" "unprognostic (2.18e-1)" "unprognostic (3.07e-1)" "unprognostic (1.49e-2)" "unprognostic (1.07e-1)" 1.1 0.4 1.0 0.5 1.9 0.2 1.5 5.4 2.1 11.6 0.6 2.1 1.6 0.4 5.1 3.4 26.9 2.2 7.1 0.5 1.0 1.0 0.4 0.2 2.0 0.9 1.6 1.2 3.4 1.1 0.2 1.4 9.2 1.9 3.7 0.6 3.0 5.4 3.1 1.2 10.2 0.7 0.9 1.2 0.3 1.0 0.7 2.0 0.6 1.7 9.0 18.6 5.1 7.2 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 1.5 0.7 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 2.9 4.7 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.0 1.9 5.4 2.1 1.0 1.0 1.6 1.2 1.9 2.0 FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557459-44559570 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 25.7;BJ hTERT+ SV40 Large T+: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 3.5;myeloid DC: 5.6;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 5.6;monocytes: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057667 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" "Nucleoplasm, Nuclear bodies" "Cell Junctions" "HPA057667: " "unprognostic (6.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.04e-2)" "unprognostic (8.83e-3)" "unprognostic (2.04e-1)" "unprognostic (5.29e-3)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (9.45e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (1.86e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-2)" "unprognostic (6.35e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" 2.3 2.8 2.3 3.9 5.8 0.9 3.2 0.7 3.1 16.1 2.9 2.1 3.0 2.9 10.8 7.6 2.4 6.6 7.7 5.8 3.2 1.5 5.0 0.5 6.9 3.1 2.1 2.9 12.1 2.7 1.6 1.9 8.4 4.9 4.2 0.8 14.3 2.9 7.9 1.8 1.1 3.6 3.3 2.0 3.7 2.1 6.5 1.8 1.1 5.3 2.4 3.1 3.8 4.3 0.2 5.6 0.0 3.5 0.0 0.8 0.6 7.5 25.7 14.7 8.4 3.3 2.9 0.3 21.3 13.0 25.5 18.4 19.8 4.4 0.0 6.7 5.3 3.5 1.7 1.8 6.1 1.9 5.0 0.8 4.2 0.1 4.3 0.1 4.4 5.5 1.4 6.2 4.2 1.0 1.6 0.2 6.4 4.0 3.4 1.9 16.1 4.8 9.8 4.4 1.3 3.3 0.3 1.9 6.4 2.7 0.7 1.6 8.2 3.6 0.4 13.8 12.2 2.6 12.5 0.6 0.4 1.8 2.5 1.4 6.3 0.0 3.5 0.0 0.1 0.2 0.0 0.0 0.0 0.8 5.6 0.2 0.0 0.2 0.0 0.0 0.2 2.6 0.0 0.6 2.3 5.8 0.7 2.1 3.2 1.5 2.1 2.9 4.9 1.8 FZD3 ENSG00000104290 "Frizzled class receptor 3" Q9NPG1 8 28494205-28574268 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 30.4;Karpas-707: 15.6;SCLC-21H: 22.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 11.8" "Group enriched" "Detected in many" 5 "dendritic cells: 11.8;T-cells: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB024995 Approved "CAB024995: " "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "prognostic favourable (1.17e-4)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (2.57e-4)" "unprognostic (1.69e-2)" "unprognostic (4.26e-4)" "unprognostic (2.11e-1)" "prognostic favourable (3.71e-4)" "unprognostic (2.86e-2)" "unprognostic (1.68e-2)" "unprognostic (1.09e-2)" "unprognostic (1.38e-1)" "unprognostic (4.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.09e-3)" 2.2 6.4 13.3 3.4 21.1 3.2 5.4 14.4 20.9 5.3 4.4 5.2 8.7 3.2 7.5 15.6 4.4 7.8 3.2 3.0 9.1 7.8 5.7 1.9 2.6 4.3 4.4 14.4 15.0 7.1 8.2 12.5 3.1 9.6 9.6 3.1 4.3 7.0 12.4 2.7 3.3 2.5 5.8 5.4 1.8 5.1 9.9 4.3 1.3 7.4 0.3 3.3 5.2 3.7 1.6 11.8 0.9 0.3 1.1 3.1 0.9 8.0 1.7 30.4 5.7 0.0 0.4 4.7 0.3 0.6 1.6 0.7 1.7 1.7 4.0 1.5 0.2 2.9 4.6 4.8 1.2 5.0 3.6 2.5 0.6 1.0 0.0 1.4 4.5 0.3 2.5 0.1 1.3 0.3 1.8 15.6 0.1 2.0 0.1 3.1 7.6 2.5 1.8 4.5 3.6 2.3 2.4 22.3 6.1 1.6 4.2 4.7 4.1 2.2 0.0 0.0 8.2 1.1 2.1 2.8 3.2 3.6 2.4 0.0 1.5 0.9 0.3 0.0 2.2 0.2 2.8 1.6 1.6 3.1 1.2 0.9 2.2 2.3 0.2 1.1 0.0 11.8 0.0 0.9 13.3 21.1 14.4 20.9 9.1 7.8 4.4 14.4 9.6 4.3 FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955391 "CD markers, Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 75.7" "Cell line enhanced" "Detected in many" "ASC diff: 25.4;Hep G2: 31.8;HSkMC: 18.3;HUVEC TERT2: 36.0;TIME: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA042328, HPA074833" Approved Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA042328: AB_10962494, HPA074833: " "unprognostic (6.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.22e-1)" "prognostic favourable (8.60e-5)" "unprognostic (1.05e-2)" "unprognostic (9.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.97e-1)" 75.7 5.3 3.4 6.0 4.8 0.5 57.8 1.5 4.3 11.5 9.0 1.4 32.6 2.0 13.1 13.5 6.3 9.6 8.7 12.5 3.1 2.2 17.0 8.9 19.0 4.7 2.9 3.2 12.8 6.0 4.4 10.1 7.3 5.5 9.3 4.3 20.0 7.1 56.0 17.9 3.7 5.4 8.6 2.8 8.6 8.2 5.5 1.6 0.5 11.4 11.1 3.0 8.3 20.7 0.4 0.2 0.8 0.4 1.4 0.3 0.0 0.5 0.4 1.0 2.0 25.4 6.6 1.4 3.2 2.9 1.2 1.3 2.7 0.3 0.0 0.7 1.0 1.0 1.2 0.5 1.0 0.1 0.8 1.0 0.8 31.8 7.5 0.0 0.0 18.3 0.2 1.1 0.2 36.0 1.4 0.1 0.8 0.8 0.0 0.0 1.5 7.2 0.0 1.9 0.0 3.5 5.2 0.2 0.3 1.3 0.3 0.5 4.6 0.0 17.6 3.0 2.0 3.6 0.6 0.1 0.5 0.0 0.4 0.0 0.8 0.7 0.3 0.1 0.3 0.2 0.1 0.2 0.3 0.2 0.1 0.4 0.2 0.3 0.8 1.4 0.4 0.2 0.0 0.0 3.4 4.8 1.5 4.3 3.1 2.2 2.9 3.2 5.5 1.6 FZD5 "C2orf31, DKFZP434E2135, HFZ5" ENSG00000163251 "Frizzled class receptor 5" Q13467 2 207762586-207769563 "G-protein coupled receptors, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.2;liver: 36.5" "Cell line enhanced" "Detected in many" "BEWO: 47.3;CACO-2: 11.5;Hep G2: 15.9;NTERA-2: 13.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA052361 Approved "HPA052361: " "unprognostic (4.97e-2)" "unprognostic (6.94e-2)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" "unprognostic (1.53e-1)" "unprognostic (2.82e-1)" "unprognostic (4.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-3)" "unprognostic (1.29e-1)" "unprognostic (8.00e-2)" "unprognostic (7.72e-2)" "unprognostic (2.51e-1)" "unprognostic (9.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.15e-3)" 5.3 5.9 1.7 5.8 3.9 3.3 6.5 0.6 2.0 4.3 25.4 7.2 8.5 17.5 2.8 1.0 3.9 1.6 5.3 1.9 1.7 2.2 12.1 36.5 12.4 0.9 3.9 1.4 4.5 20.8 1.2 6.1 6.5 2.6 6.4 14.4 6.6 3.7 3.9 2.5 1.4 35.2 2.5 1.9 2.8 10.8 0.8 4.2 1.3 18.5 1.8 2.9 2.6 3.4 0.3 1.4 0.5 1.1 0.2 0.4 0.4 1.4 2.6 0.1 1.4 1.2 0.0 47.3 0.2 0.3 0.3 0.3 11.5 2.7 0.2 3.2 0.1 2.1 4.0 1.7 0.3 0.1 3.1 3.3 1.2 15.9 0.9 0.6 0.9 0.1 1.7 0.5 1.3 0.4 6.5 0.5 0.3 1.0 0.3 0.8 13.8 0.9 0.8 1.5 0.6 3.3 5.0 2.2 0.3 0.6 0.2 0.6 0.7 0.6 0.1 0.7 1.3 1.4 1.0 0.7 1.7 0.5 0.9 0.7 0.2 0.3 1.1 0.2 0.1 0.8 0.4 0.1 0.0 0.0 1.4 0.3 0.1 0.2 0.5 0.2 0.4 0.1 0.1 0.4 1.7 3.9 0.6 2.0 1.7 2.2 3.9 1.4 2.6 4.2 FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTCEpi: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 7.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Approved "Plasma membrane" "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavourable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" 13.1 9.2 3.4 5.2 3.8 0.5 13.3 4.3 5.9 12.1 10.7 3.5 8.6 4.0 12.0 16.4 17.9 17.8 12.3 9.6 3.7 3.8 17.4 5.8 17.1 4.7 4.2 2.9 11.6 14.4 21.3 27.2 14.1 10.0 12.4 4.9 11.6 15.3 8.8 4.3 16.9 7.7 12.7 4.2 6.1 8.0 7.2 1.5 10.9 21.2 18.7 14.7 15.9 11.3 1.7 1.0 0.2 0.0 7.9 2.2 0.5 19.4 4.0 9.4 0.0 2.2 7.0 5.8 10.4 11.4 9.3 6.1 2.1 15.0 0.0 17.8 9.2 28.9 5.3 21.5 16.5 4.4 6.4 10.3 4.5 2.6 31.1 0.0 0.0 7.9 41.5 9.8 30.4 19.0 1.0 8.5 9.9 8.0 9.1 0.8 2.2 6.9 0.7 4.5 0.0 18.8 12.3 3.3 2.6 14.5 7.6 18.8 0.0 3.5 1.5 2.2 10.9 8.3 10.6 2.2 1.1 4.2 6.1 0.0 13.4 0.0 0.0 0.2 0.6 0.0 0.0 0.9 2.1 0.9 1.0 1.7 2.2 1.0 0.0 7.9 0.0 0.2 0.6 0.5 3.4 3.8 4.3 5.9 3.7 3.8 4.2 2.9 10.0 1.5 FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202034587-202038445 "G-protein coupled receptors, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 25.2;CAPAN-2: 31.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 15 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles Vesicles "HPA059979: , HPA069165: , HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavourable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" 4.8 1.6 3.2 4.7 6.5 0.0 9.9 23.3 4.5 8.5 17.8 2.0 3.3 3.9 9.7 9.4 9.1 8.6 3.7 8.7 10.8 0.7 4.1 0.8 3.0 4.0 0.8 6.2 17.4 0.8 0.0 4.9 3.2 3.8 12.4 3.4 6.1 13.4 16.2 13.5 5.3 5.6 17.3 3.0 2.0 3.1 3.2 3.0 0.8 2.6 4.3 3.2 13.1 8.7 0.0 0.0 1.5 0.0 0.0 0.0 0.0 4.6 2.5 17.2 5.5 5.7 4.2 7.3 19.6 25.2 6.3 7.4 16.1 31.4 0.0 11.7 13.4 5.0 3.1 0.7 7.3 2.3 4.1 0.5 1.1 1.3 3.8 0.9 1.0 4.1 0.5 3.3 2.0 0.0 1.3 1.3 5.1 2.1 0.0 2.8 17.9 1.7 1.9 3.2 0.5 1.0 3.0 2.8 6.2 2.5 0.2 3.2 1.8 1.2 0.0 12.2 4.3 7.5 2.5 1.2 0.9 0.0 2.5 0.2 8.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 6.5 23.3 4.5 10.8 0.7 0.8 6.2 3.8 3.0 FZD8 ENSG00000177283 "Frizzled class receptor 8" Q9H461 10 35638249-35642278 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 27.3;U-138 MG: 10.3;U-251 MG: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA045025, HPA071142" Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA045025: AB_10795888, HPA071142: " "unprognostic (1.20e-1)" "unprognostic (4.42e-3)" "unprognostic (1.85e-2)" "unprognostic (1.97e-1)" "unprognostic (2.21e-2)" "unprognostic (2.94e-1)" "unprognostic (1.61e-1)" "unprognostic (1.08e-3)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "prognostic favourable (8.21e-4)" "unprognostic (4.92e-2)" "unprognostic (2.25e-1)" "unprognostic (4.85e-2)" "unprognostic (1.68e-1)" "unprognostic (7.34e-3)" "unprognostic (1.19e-1)" 8.9 2.6 7.4 2.7 5.1 0.7 4.9 0.5 8.5 5.2 10.4 4.9 0.6 1.8 3.4 2.2 2.1 7.9 3.9 12.5 12.0 1.7 13.1 5.0 9.5 4.3 2.7 3.8 4.9 9.5 6.0 4.0 1.8 7.1 3.4 4.6 14.2 4.5 3.5 5.8 4.6 2.6 3.6 1.4 21.3 10.4 4.1 5.5 3.3 14.7 2.4 3.0 2.8 5.4 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 2.9 0.5 0.0 1.2 0.0 1.8 3.2 0.1 0.1 0.1 0.3 0.5 0.0 0.5 1.4 1.0 0.3 1.0 0.0 0.0 8.4 0.0 0.3 0.1 0.6 0.0 0.2 1.0 4.1 6.7 2.6 2.3 0.1 0.0 0.9 1.2 0.0 0.0 2.7 27.3 2.6 1.7 0.0 5.2 0.2 8.2 0.2 0.6 0.1 0.0 0.0 0.4 5.4 10.3 1.6 5.0 8.8 0.0 0.0 0.0 5.9 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.4 5.1 0.5 8.5 12.0 1.7 2.7 3.8 7.1 5.5 GABBR1 "GPRC3A, hGB1a" ENSG00000204681 "Gamma-aminobutyric acid type B receptor subunit 1" Q9UBS5 6 29555629-29633976 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.8" "Cell line enhanced" "Detected in many" "AN3-CA: 8.0;HEL: 7.7;U-2 OS: 8.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 1.8;plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050483, HPA058459" Uncertain Approved Centrosome "Intracellular and membrane" Centrosome "HPA050483: , HPA058459: " "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (3.22e-3)" "unprognostic (2.93e-3)" "unprognostic (3.37e-1)" "unprognostic (2.65e-1)" "unprognostic (7.95e-4)" "unprognostic (5.44e-2)" "unprognostic (4.24e-2)" "unprognostic (1.14e-1)" "prognostic favourable (2.54e-5)" "unprognostic (1.23e-3)" "prognostic unfavourable (3.77e-10)" "unprognostic (3.82e-2)" "unprognostic (2.26e-1)" "unprognostic (3.87e-2)" "unprognostic (2.55e-2)" 14.0 7.4 33.6 7.0 47.2 8.2 4.2 29.1 53.8 6.9 5.6 17.3 3.0 2.3 18.1 1.9 2.9 7.9 4.1 4.6 24.8 21.4 2.9 2.0 6.9 6.6 15.6 33.7 7.8 5.1 1.8 5.8 5.0 22.3 12.8 3.2 4.4 13.0 13.3 8.5 18.3 6.1 5.5 14.9 24.2 6.1 4.3 15.4 0.0 3.9 0.1 5.2 4.0 5.9 1.8 1.7 0.0 0.5 0.0 0.4 0.3 2.9 0.0 1.9 8.0 0.9 2.1 2.1 2.0 0.8 1.8 0.5 2.3 0.1 1.4 2.0 0.0 2.4 0.9 0.0 0.0 7.2 3.4 7.7 3.4 0.0 1.2 0.3 4.0 0.0 0.0 1.6 0.0 1.0 6.6 0.0 0.3 1.9 0.7 0.1 0.6 1.1 3.5 0.7 0.1 0.3 0.0 0.5 1.3 0.5 0.0 3.3 1.5 1.1 4.5 3.2 8.3 0.3 3.7 7.0 0.7 0.0 1.8 3.5 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.3 1.8 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.3 33.6 47.2 29.1 53.8 24.8 21.4 15.6 33.7 22.3 15.4 GABBR2 "GABABR2, GPR51, GPRC3B, HG20" ENSG00000136928 "Gamma-aminobutyric acid type B receptor subunit 2" O75899 9 98288082-98709197 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 52.7" "Cell line enhanced" "Detected in some" "BJ: 10.9;fHDF/TERT166: 5.4;HUVEC TERT2: 22.5;U-138 MG: 8.8" "Group enriched" "Detected in many" 10 "glioma: 7.2;thyroid cancer: 11.6;urothelial cancer: 3.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013820, HPA031684, CAB079065" Enhanced Approved "CAB079065: , HPA013820: AB_1849364, HPA031684: " "unprognostic (2.00e-1)" "unprognostic (7.56e-2)" "unprognostic (3.75e-1)" "unprognostic (3.09e-5)" "unprognostic (2.52e-1)" "unprognostic (1.16e-1)" "unprognostic (2.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.66e-1)" "unprognostic (4.43e-2)" "unprognostic (1.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.76e-2)" "unprognostic (3.52e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-2)" "unprognostic (3.45e-2)" 0.9 4.4 13.6 1.0 14.6 0.8 0.9 19.7 52.7 0.8 0.9 2.1 0.0 0.8 1.1 1.1 0.9 0.8 0.9 0.9 14.6 11.1 0.9 0.9 1.0 0.9 7.6 17.6 0.8 0.8 0.9 0.3 0.9 10.3 0.9 0.8 0.6 0.9 0.9 3.2 0.9 0.8 1.0 2.2 0.9 1.0 1.3 0.2 0.0 2.3 0.0 1.1 1.5 0.1 0.7 0.7 1.7 1.1 1.7 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 1.0 10.9 2.2 2.3 4.2 0.0 0.1 0.0 0.7 5.4 0.0 0.1 0.2 0.8 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.8 0.2 22.5 0.2 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.6 3.1 0.0 0.0 2.8 0.0 0.0 0.1 1.0 8.8 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.7 0.4 0.8 0.6 0.7 1.0 0.7 0.7 0.7 0.4 0.6 0.8 0.9 1.2 1.7 1.1 0.7 1.0 0.4 13.6 14.6 19.7 35.0 14.6 11.1 7.6 17.6 10.3 0.2 GALR2 GALNR2 ENSG00000182687 "Galanin receptor 2" O43603 17 76074794-76077541 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 3.5;intestine: 13.1;lymphoid tissue: 9.8;smooth muscle: 6.4" "Cell line enhanced" "Detected in some" "HaCaT: 3.1;NTERA-2: 4.6;THP-1: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "neutrophil: 1.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044513 Approved "HPA044513: AB_10962510" "unprognostic (1.26e-2)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (1.37e-2)" "unprognostic (2.62e-2)" "unprognostic (3.54e-1)" "unprognostic (3.49e-2)" "unprognostic (3.43e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-1)" "unprognostic (9.32e-5)" "unprognostic (2.31e-1)" "unprognostic (2.11e-3)" "unprognostic (1.24e-1)" "unprognostic (2.39e-1)" "unprognostic (4.04e-2)" "unprognostic (8.14e-2)" 0.3 0.1 0.0 9.8 0.1 3.5 0.0 0.0 0.3 0.3 13.1 0.0 0.0 0.6 0.0 0.0 1.1 0.1 0.5 0.1 1.4 0.8 0.0 0.2 0.0 0.1 0.2 0.0 0.2 0.3 0.0 0.1 0.4 0.6 0.2 0.1 0.0 0.1 0.0 0.0 0.3 9.0 6.4 1.4 0.2 0.4 0.3 0.0 0.0 0.0 1.1 1.2 1.0 0.2 0.0 1.1 1.4 0.9 0.5 0.4 0.7 0.2 1.9 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.3 0.0 2.1 0.4 0.6 0.3 0.0 3.1 0.0 0.1 0.0 0.3 2.5 0.0 1.5 2.8 0.3 0.6 0.5 0.0 0.0 0.3 0.0 0.1 0.1 0.5 0.1 1.1 0.2 0.3 4.6 2.9 0.1 0.6 0.8 0.0 0.2 0.2 0.1 1.7 0.7 0.3 0.6 6.8 0.2 0.2 0.6 0.2 0.4 0.7 0.4 2.6 0.0 0.1 0.0 0.0 0.9 0.0 0.4 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.4 0.5 0.4 1.1 0.0 0.7 0.0 0.1 0.0 0.3 1.4 0.8 0.2 0.0 0.6 0.0 GCGR GGR ENSG00000215644 "Glucagon receptor" P47871 17 81804132-81814013 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 68.8" "Cell line enhanced" "Detected in some" "HeLa: 3.8;MCF7: 6.0;SK-BR-3: 5.2;U-87 MG: 6.0" "Cancer enhanced" "Detected in many" "liver cancer: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 0.9" "Low region specificity" "Detected in all" HPA071228 Approved "Golgi apparatus" "Golgi apparatus" "HPA071228: " "unprognostic (3.28e-4)" "unprognostic (9.30e-2)" "unprognostic (2.20e-1)" "unprognostic (1.53e-4)" "unprognostic (1.11e-1)" "unprognostic (2.30e-3)" "unprognostic (4.38e-2)" "unprognostic (1.79e-3)" "unprognostic (2.18e-1)" "unprognostic (2.77e-1)" "unprognostic (3.09e-1)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (5.99e-3)" "unprognostic (1.71e-1)" "unprognostic (1.17e-3)" "unprognostic (8.36e-3)" 0.2 3.9 0.1 0.6 0.3 0.0 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.0 11.4 68.8 0.1 0.1 0.1 0.1 0.1 0.5 3.9 0.1 0.1 0.5 0.2 0.0 1.4 0.3 0.1 0.1 0.9 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.2 0.6 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.8 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 1.5 0.0 5.2 0.0 0.0 0.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.3 0.1 0.0 0.1 0.1 0.5 0.1 GIPR ENSG00000010310 "Gastric inhibitory polypeptide receptor" P48546 19 45668244-45683724 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.3;stomach 1: 26.1" "Cell line enhanced" "Detected in some" "HDLM-2: 7.9;HMC-1: 17.9;SCLC-21H: 11.9;U-266/70: 14.7" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 4.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB022710 Uncertain "CAB022710: " "unprognostic (2.40e-2)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (3.70e-4)" "unprognostic (1.82e-2)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.85e-3)" "unprognostic (2.78e-1)" "unprognostic (1.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-2)" "unprognostic (2.59e-2)" 8.0 0.4 2.3 4.5 8.4 2.4 6.6 1.8 10.5 2.9 4.5 9.4 0.1 4.3 0.7 1.5 1.8 10.0 1.8 12.3 3.7 2.6 1.7 0.5 4.8 3.6 21.3 1.4 1.0 8.5 9.0 2.0 0.4 6.3 5.3 5.8 2.6 5.8 0.6 0.4 3.3 3.6 0.5 4.6 4.1 26.1 0.4 16.2 0.2 1.8 0.8 4.4 3.0 3.3 2.3 1.2 2.5 0.8 4.1 2.3 0.7 0.7 0.4 1.2 0.7 0.5 0.0 0.2 0.9 0.7 0.1 0.7 0.4 3.4 1.5 0.5 0.6 1.8 0.3 0.1 0.1 7.9 0.3 1.4 0.8 0.3 0.1 0.4 17.9 0.0 0.3 0.2 0.2 0.1 3.6 1.9 0.0 0.2 0.1 1.1 0.1 0.9 0.5 0.3 3.5 0.4 0.9 11.9 1.1 0.1 0.8 0.1 1.7 2.5 0.3 0.0 0.5 0.3 0.3 14.7 0.2 0.3 0.5 1.4 0.3 2.5 0.7 2.0 2.3 0.8 0.8 0.9 0.9 1.6 0.9 2.3 1.1 1.8 2.2 4.1 0.5 1.2 1.8 0.7 2.3 8.4 1.8 10.5 3.7 2.6 21.3 1.4 6.3 16.2 GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892102 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "gallbladder: 32.7" "Cell line enriched" "Detected in some" 5 "HeLa: 41.8" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Group enriched" "Detected in some" 4 "basal ganglia: 2.9;cerebral cortex: 4.1;olfactory region: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cerebral cortex: 2.1;hippocampal formation: 2.6" "Low region specificity" "Detected in many" "CAB022690, HPA049244" Supported Supported "Plasma membrane" "Plasma membrane" "CAB022690: , HPA049244: " "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" 7.9 0.7 0.6 2.0 2.9 0.0 2.6 0.3 4.3 6.6 14.5 0.0 1.7 12.4 1.9 0.4 5.3 1.4 32.7 0.9 0.6 0.5 0.4 3.2 1.4 0.7 0.6 1.6 0.8 2.1 0.0 0.3 1.5 0.5 8.4 7.5 0.8 0.4 0.2 0.3 0.3 15.4 15.6 0.6 0.3 4.9 1.1 0.2 0.0 0.5 0.1 0.4 13.5 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 41.8 0.3 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.3 4.1 0.6 0.5 0.6 1.6 0.5 0.2 GNRHR "GRHR, LHRHR" ENSG00000109163 "Gonadotropin releasing hormone receptor" P30968 4 67739328-67754360 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, FDA approved drug targets, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "pituitary gland: 56.6" "Cell line enhanced" "Detected in some" "K-562: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" HPA013424 Enhanced "HPA013424: " "unprognostic (2.77e-1)" "unprognostic (1.58e-1)" "unprognostic (4.05e-1)" "unprognostic (1.78e-1)" "unprognostic (4.65e-1)" "unprognostic (8.75e-3)" "unprognostic (3.09e-2)" "unprognostic (1.34e-1)" "unprognostic (1.90e-1)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.63e-1)" "unprognostic (9.03e-2)" "unprognostic (3.23e-2)" "unprognostic (9.67e-2)" "unprognostic (1.22e-3)" "unprognostic (3.99e-2)" 0.1 3.9 0.1 0.4 0.2 0.2 0.1 0.3 1.7 0.3 0.1 0.1 0.1 0.7 0.1 0.1 1.6 0.0 0.2 0.2 0.2 0.2 0.1 0.1 0.1 1.1 0.1 0.1 0.2 0.3 0.0 56.6 0.1 0.5 0.2 0.0 0.1 0.3 0.1 0.2 0.9 0.1 0.1 0.1 0.2 0.3 0.3 0.1 0.2 1.0 0.1 0.4 0.1 0.5 1.3 0.2 0.0 0.0 0.4 0.3 0.0 0.2 1.5 1.5 1.6 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.5 1.7 1.2 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.5 0.2 0.3 0.7 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.7 0.6 0.4 0.9 0.0 0.6 1.2 0.6 0.0 0.0 0.8 2.0 0.0 0.3 0.0 0.3 0.2 1.0 0.1 0.2 0.6 0.2 1.1 0.3 0.6 1.4 0.8 0.9 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.1 0.0 0.0 1.3 0.1 0.3 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.2 0.3 0.3 0.2 0.2 0.1 0.1 0.5 0.1 GPBAR1 "BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5" ENSG00000179921 "G protein-coupled bile acid receptor 1" Q8TDU6 2 218259496-218263859 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 85.6;gallbladder: 73.8" "Cell line enhanced" "Detected in some" "ASC diff: 3.0;HHSteC: 5.0;U-937: 5.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "intermediate monocyte: 85.6;non-classical monocyte: 78.5" "Lineage enriched" "Detected in many" 5 "monocytes: 85.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA062890 Enhanced "HPA062890: " "unprognostic (8.47e-2)" "unprognostic (3.72e-3)" "unprognostic (1.88e-2)" "unprognostic (9.49e-2)" "unprognostic (1.44e-2)" "unprognostic (4.66e-2)" "unprognostic (2.54e-1)" "unprognostic (2.63e-1)" "unprognostic (8.76e-3)" "unprognostic (4.32e-2)" "unprognostic (4.64e-2)" "unprognostic (1.55e-1)" "unprognostic (7.40e-7)" "unprognostic (4.18e-2)" "unprognostic (4.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.29e-1)" 19.9 1.1 0.3 2.6 0.4 1.8 11.4 0.2 0.4 0.7 2.7 0.5 0.8 1.0 1.1 1.4 1.3 0.9 73.8 3.8 0.2 0.0 3.2 1.7 2.2 3.8 0.4 0.2 1.4 1.5 0.0 0.7 8.9 0.4 2.0 0.5 0.9 0.5 0.9 0.8 0.8 3.2 10.3 0.2 6.5 5.5 1.5 0.2 1.0 1.5 1.8 0.6 3.2 0.7 0.0 17.4 0.8 85.6 0.0 0.1 15.8 0.2 0.1 0.4 0.0 3.0 0.1 0.9 0.0 0.4 0.0 0.1 0.8 0.4 0.2 0.3 0.3 0.1 0.1 0.3 0.0 0.0 0.7 0.3 0.5 0.4 5.0 0.3 1.4 0.0 2.5 0.0 0.0 0.2 0.3 0.4 0.6 0.3 0.2 0.7 0.2 0.0 0.2 0.0 0.1 1.6 1.1 2.6 2.3 0.2 0.7 0.4 0.0 0.8 0.0 0.1 0.3 0.2 0.2 0.3 0.7 0.1 0.3 5.0 0.2 0.0 36.4 0.0 0.1 85.6 0.1 0.0 0.0 0.1 17.4 0.0 0.0 0.0 0.8 0.0 78.5 0.7 0.1 15.8 0.3 0.4 0.2 0.4 0.2 0.0 0.4 0.2 0.4 0.2 GPER1 "CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR" ENSG00000164850 "G protein-coupled estrogen receptor 1" Q99527 7 1082208-1093815 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 9.9;Daudi: 10.4;Hep G2: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.3;intermediate monocyte: 4.2;myeloid DC: 8.4" "Group enriched" "Detected in many" 18 "dendritic cells: 8.4;monocytes: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027052 Approved "HPA027052: AB_10612112" "unprognostic (4.74e-2)" "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "prognostic favourable (1.17e-4)" "unprognostic (2.17e-1)" "unprognostic (6.17e-2)" "unprognostic (3.45e-1)" "unprognostic (6.38e-2)" "unprognostic (2.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.58e-1)" "unprognostic (7.26e-2)" "unprognostic (7.78e-2)" 14.2 10.9 12.1 3.6 13.2 1.2 11.5 5.1 11.1 6.4 7.1 5.6 3.5 2.0 5.4 1.8 5.5 4.8 3.2 6.0 8.3 6.2 7.4 19.5 25.6 6.4 8.6 8.7 3.3 4.0 1.8 4.7 13.3 6.1 6.8 3.7 5.2 4.2 11.8 8.6 2.8 2.6 5.5 4.1 6.5 23.9 2.2 8.6 1.3 16.5 2.3 2.8 6.4 7.2 0.3 8.4 0.0 4.3 0.0 0.0 1.6 0.9 0.3 0.2 9.9 2.4 2.4 1.0 5.7 3.8 1.8 3.3 0.2 0.2 10.4 0.9 7.1 0.5 0.1 0.0 0.2 2.1 1.8 0.0 1.2 19.0 0.3 0.1 0.6 1.3 0.0 1.1 0.0 0.5 0.1 0.1 0.4 0.6 0.0 0.3 1.9 6.8 0.9 0.0 0.0 0.2 0.0 0.1 3.9 0.0 0.4 2.1 0.2 0.1 1.4 0.4 2.6 6.0 1.8 0.0 0.0 3.6 3.3 0.1 0.2 0.0 4.3 0.0 0.0 4.2 0.0 0.3 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.6 12.1 13.2 5.1 11.1 8.3 6.2 8.6 8.7 6.1 8.6 GPR1 ENSG00000183671 "G protein-coupled receptor 1" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 19.1" "Group enriched" "Detected in some" 4 "HHSteC: 52.5;hTCEpi: 23.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basal ganglia: 10.7;pons and medulla: 6.6" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" 2.3 5.0 0.5 0.6 10.7 0.1 1.7 0.4 1.2 4.1 0.6 4.8 1.6 0.2 1.3 0.7 6.6 1.1 2.7 3.8 1.6 0.5 0.7 0.0 0.5 3.1 0.2 0.3 3.2 0.1 0.0 0.4 19.1 6.6 0.7 0.6 1.1 1.5 0.4 1.5 6.7 0.5 2.3 0.3 0.2 0.2 1.6 1.0 0.0 0.7 2.2 1.2 3.1 7.7 0.5 0.1 1.4 0.2 0.5 0.2 0.6 0.8 0.1 0.7 0.0 0.1 2.9 0.2 5.4 9.3 3.3 2.8 0.0 0.0 0.0 0.3 2.7 0.1 0.2 0.0 1.1 0.0 0.1 0.0 1.8 0.0 52.5 0.0 0.0 2.1 23.7 4.8 7.7 0.0 0.0 0.0 6.7 0.0 0.0 0.0 2.6 0.5 0.0 0.0 0.0 0.0 0.0 0.1 2.3 1.1 0.0 0.0 0.0 0.0 0.1 4.1 1.8 4.7 0.4 0.0 0.0 0.0 1.4 0.0 0.1 1.3 0.2 0.3 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.5 0.2 0.2 1.4 0.5 0.1 0.1 0.2 0.6 0.5 10.7 0.4 1.2 1.6 0.5 0.2 0.3 6.6 1.0 GPR101 ENSG00000165370 "G protein-coupled receptor 101" Q96P66 X 137030148-137031674 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "brain: 11.1" "Cell line enriched" "Detected in single" 4 "HEK 293: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 44.7" "Low region specificity" "Detected in many" HPA001084 Uncertain "HPA001084: AB_1078920" 0.0 0.0 0.0 0.0 11.1 0.1 0.0 0.0 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR12 "GPCR21, PPP1R84" ENSG00000132975 "G protein-coupled receptor 12" P47775 13 26755200-26760785 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 29.4;salivary gland: 7.7" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 17.7" "Group enriched" "Detected in some" 7 "breast cancer: 0.5;glioma: 0.8;ovarian cancer: 0.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "basophil: 2.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA050972 Uncertain "HPA050972: " "unprognostic (2.37e-2)" "unprognostic (9.64e-3)" "unprognostic (3.75e-1)" "unprognostic (3.30e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-2)" "unprognostic (1.42e-1)" "unprognostic (7.35e-2)" "unprognostic (5.53e-2)" "unprognostic (3.83e-2)" "unprognostic (2.40e-1)" 1.1 0.7 4.9 0.5 29.4 0.9 4.6 17.7 14.6 1.4 0.7 1.6 0.0 0.7 0.6 0.5 0.8 2.5 0.7 0.7 5.6 2.6 0.6 0.5 0.7 0.6 2.2 4.8 0.6 0.5 0.5 0.7 1.6 1.1 0.6 0.7 1.9 7.7 0.6 0.9 4.4 0.9 0.9 0.7 0.8 0.7 0.8 6.6 0.0 0.6 0.0 0.6 0.6 0.0 0.3 0.2 2.4 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.5 0.1 0.1 0.2 0.0 0.1 4.9 29.4 17.7 8.4 5.6 2.6 2.2 4.8 1.1 6.6 GPR132 G2A ENSG00000183484 "G protein-coupled receptor 132" Q9UNW8 14 105049389-105065445 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 14.0;lymphoid tissue: 20.2" "Group enriched" "Detected in some" 6 "HDLM-2: 19.8;Karpas-707: 20.5;THP-1: 6.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA029694, HPA029695" Supported "HPA029694: AB_10600213, HPA029695: AB_10601984" "unprognostic (2.71e-3)" "prognostic favourable (3.21e-4)" "unprognostic (1.68e-2)" "unprognostic (1.07e-3)" "unprognostic (1.16e-1)" "prognostic favourable (6.44e-4)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (3.35e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (4.18e-1)" "prognostic unfavourable (1.71e-5)" "unprognostic (6.71e-2)" "unprognostic (4.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.72e-1)" 2.9 1.2 1.8 11.5 2.7 9.3 1.5 0.7 1.8 1.5 2.4 3.3 0.0 1.3 1.0 1.6 1.4 3.0 2.9 1.4 1.6 1.2 4.5 0.8 5.9 20.2 3.3 1.0 1.1 0.8 0.4 0.9 2.0 2.2 1.4 1.2 1.5 3.0 0.7 0.8 3.5 6.6 1.0 3.7 15.4 2.1 0.6 2.5 4.3 6.5 0.7 17.4 3.1 1.9 8.6 9.1 9.8 14.0 9.3 10.6 6.6 0.0 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.4 2.6 0.5 0.0 0.6 0.0 0.0 0.0 19.8 0.3 0.5 0.1 0.0 0.0 1.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.5 0.0 1.9 0.1 0.0 1.5 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 6.2 0.3 0.0 0.1 0.0 0.2 0.5 1.9 0.2 0.0 1.8 0.0 9.8 9.0 8.6 10.6 12.5 9.9 7.2 8.2 9.2 9.1 8.6 8.6 8.9 7.9 9.3 14.0 5.2 5.8 6.6 1.8 2.7 0.7 1.8 1.6 1.2 3.3 1.0 2.2 2.5 GPR135 "HUMNPIIY20, PAFR" ENSG00000181619 "G protein-coupled receptor 135" Q8IZ08 14 59429022-59465342 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045337 Uncertain "HPA045337: AB_10960528" "unprognostic (1.55e-1)" "unprognostic (3.00e-1)" "unprognostic (6.09e-3)" "unprognostic (1.14e-1)" "unprognostic (4.20e-2)" "unprognostic (8.47e-2)" "unprognostic (3.22e-1)" "unprognostic (3.91e-2)" "unprognostic (4.64e-2)" "unprognostic (1.09e-1)" "unprognostic (2.47e-2)" "unprognostic (1.55e-1)" "unprognostic (2.75e-5)" "unprognostic (1.33e-2)" "unprognostic (1.90e-1)" "unprognostic (2.71e-2)" "unprognostic (2.68e-3)" 2.1 3.7 2.0 1.2 3.4 0.4 1.2 3.2 2.7 2.9 1.8 2.1 2.3 0.5 3.8 3.4 1.6 6.7 2.7 3.0 2.0 3.3 1.5 0.9 1.3 1.1 1.2 3.7 4.4 4.7 6.8 12.3 1.3 4.7 4.3 1.2 1.7 0.7 6.2 1.0 0.7 1.1 2.7 0.9 1.0 1.4 34.1 1.8 0.4 3.6 0.2 0.7 2.7 2.4 0.1 0.4 0.0 0.4 0.3 1.6 0.1 1.1 1.2 2.1 2.5 1.8 2.6 1.7 2.2 1.3 1.5 1.6 0.5 2.3 1.0 1.7 2.7 1.3 1.0 0.9 2.0 2.1 0.8 0.7 5.7 0.8 1.5 1.3 1.0 1.5 1.6 2.2 1.0 1.0 1.2 1.7 2.2 0.7 0.4 3.1 1.5 4.6 1.5 1.6 1.1 1.5 1.0 2.7 3.3 5.1 0.9 0.2 1.1 0.5 3.7 3.8 3.0 1.1 2.5 0.4 0.0 0.9 1.3 1.5 1.7 0.0 0.3 0.0 0.2 0.0 0.3 0.0 0.7 0.0 0.4 0.1 0.2 0.4 0.0 0.3 0.4 0.0 1.6 0.1 2.0 3.4 3.2 2.6 2.0 3.3 1.2 3.7 4.7 1.8 GPR139 PGR3 ENSG00000180269 "G protein-coupled receptor 139" Q6DWJ6 16 20031485-20073917 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 2.8;endometrium 1: 2.1;smooth muscle: 1.0" "Cell line enriched" "Detected in single" 10 "NTERA-2: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046596 Uncertain "HPA046596: " "unprognostic (2.94e-1)" 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR142 PGR2 ENSG00000257008 "G protein-coupled receptor 142" Q7Z601 17 74367407-74372622 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.3;lymphoid tissue: 1.3" "Cell line enhanced" "Detected in single" "U-937: 1.1" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031392 Uncertain Uncertain "Plasma membrane,Cell Junctions,Cytosol" "Plasma membrane, Cytosol" "Cell Junctions" "HPA031392: AB_10601935" "unprognostic (6.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "unprognostic (6.54e-5)" "unprognostic (4.16e-2)" "unprognostic (4.85e-7)" "unprognostic (3.95e-2)" "unprognostic (7.72e-4)" "unprognostic (1.93e-1)" "unprognostic (1.68e-3)" 0.2 0.0 0.0 1.3 0.1 0.0 0.1 1.3 0.2 0.3 0.1 0.8 0.6 0.0 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR143 OA1 ENSG00000101850 "G protein-coupled receptor 143" P51810 X 9725346-9786297 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "retina: 51.5" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 57.3" "Cancer enriched" "Detected in all" 9 "melanoma: 84.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "basophil: 5.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 5.0" "Not detected" "Not detected" HPA003648 Enhanced "HPA003648: " "unprognostic (4.60e-2)" "prognostic favourable (8.73e-4)" "unprognostic (7.43e-3)" "unprognostic (5.41e-2)" "unprognostic (4.62e-3)" "unprognostic (2.00e-2)" "unprognostic (3.05e-1)" "unprognostic (2.64e-3)" "unprognostic (3.78e-1)" "unprognostic (5.89e-2)" "unprognostic (8.18e-2)" "unprognostic (8.40e-2)" "prognostic favourable (2.45e-5)" "unprognostic (2.75e-1)" "unprognostic (2.07e-1)" "unprognostic (8.76e-2)" "unprognostic (1.59e-2)" 0.8 1.3 4.2 0.0 7.6 0.0 2.1 1.5 4.5 2.0 1.6 3.0 3.6 0.6 3.9 7.0 2.8 3.7 1.1 0.4 3.4 3.7 6.6 2.0 1.2 0.4 5.7 3.1 4.5 2.1 3.0 2.0 7.9 6.3 3.4 1.8 51.5 4.1 6.3 0.2 11.5 0.5 1.2 4.3 0.2 0.9 1.0 2.2 1.0 4.2 1.0 1.8 1.8 1.1 0.5 0.1 5.0 0.3 0.1 0.3 0.0 0.6 0.1 1.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.9 0.0 1.3 0.0 0.6 0.0 0.0 2.5 0.0 0.0 0.0 4.3 0.0 0.0 4.1 0.0 0.0 0.0 0.0 8.3 1.1 0.3 0.0 0.1 0.0 57.3 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.3 0.2 0.3 0.1 0.1 0.4 0.1 0.1 0.1 0.5 0.1 0.2 0.8 0.1 0.1 0.0 0.0 0.0 4.2 7.6 1.5 4.5 3.4 3.7 5.7 3.1 6.3 2.2 GPR148 PGR6 ENSG00000173302 "G protein-coupled receptor 148" Q8TDV2 2 130729070-130730336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 2.6;pancreas: 1.1;pituitary gland: 2.2;stomach 1: 3.5" "Group enriched" "Detected in some" 11 "CACO-2: 2.5;SCLC-21H: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA060527 Uncertain "HPA060527: " "unprognostic (7.16e-4)" "unprognostic (3.38e-1)" 0.0 0.2 0.1 0.0 0.4 0.0 0.0 2.6 0.4 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR149 "IEDA, PGR10, R35" ENSG00000174948 "G protein-coupled receptor 149" Q86SP6 3 154337672-154429715 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "brain: 23.5;pituitary gland: 6.5;seminal vesicle: 8.7" "Cell line enhanced" "Detected in single" "SCLC-21H: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basal ganglia: 23.5;pons and medulla: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 15.0" "Low region specificity" "Detected in all" HPA018020 Uncertain "HPA018020: AB_1849334" 0.2 0.3 0.2 0.2 23.5 0.2 0.2 0.0 0.8 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.2 1.9 0.2 0.2 0.2 0.2 0.8 0.0 0.2 0.2 0.2 6.5 0.2 6.5 0.3 0.3 0.4 0.2 8.7 0.2 0.3 0.3 0.2 0.6 0.2 0.5 1.1 2.1 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 23.5 0.0 0.8 0.2 1.9 0.8 0.0 6.5 2.1 GPR15 ENSG00000154165 "G protein-coupled receptor 15" P49685 3 98531899-98533150 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 12.9;intestine: 27.1;lymphoid tissue: 26.3;urinary bladder: 9.4" "Group enriched" "Detected in some" 22 "HDLM-2: 10.9;U-266/70: 4.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 4.4;memory CD4 T-cell: 12.9;memory CD8 T-cell: 6.1;T-reg: 12.9" "Group enriched" "Detected in many" 30 "B-cells: 4.4;T-cells: 12.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA013775 Approved "HPA013775: AB_1849264" "unprognostic (8.03e-2)" "unprognostic (1.04e-2)" "unprognostic (3.72e-3)" "unprognostic (5.66e-2)" "unprognostic (9.48e-3)" "unprognostic (5.60e-5)" "unprognostic (5.17e-1)" "unprognostic (6.77e-3)" "unprognostic (3.96e-1)" "unprognostic (3.03e-2)" "unprognostic (2.82e-1)" "unprognostic (2.83e-1)" "unprognostic (4.04e-3)" "unprognostic (4.23e-3)" "unprognostic (1.89e-1)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" 0.9 0.1 0.1 13.4 0.1 0.0 2.5 0.1 0.2 1.1 15.3 0.1 0.1 1.8 0.1 0.1 2.6 0.2 2.1 0.2 0.1 0.1 0.3 0.4 1.9 24.9 0.1 0.4 0.4 0.1 0.0 0.2 0.1 0.3 1.4 27.1 0.3 4.6 0.7 0.1 0.4 11.8 1.5 0.2 4.3 1.1 0.2 0.1 3.6 0.7 2.0 26.3 9.4 2.4 4.4 0.2 0.2 0.0 0.0 12.9 2.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.8 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.4 4.4 12.9 6.1 0.0 0.7 0.6 1.0 0.2 0.0 0.0 0.2 12.9 2.8 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.3 0.1 GPR150 PGR11 ENSG00000178015 "G protein-coupled receptor 150" Q8NGU9 5 95620078-95622142 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 11.5;pancreas: 13.4" "Cell line enhanced" "Detected in some" "ASC diff: 3.8;SiHa: 3.1;TIME: 6.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "MAIT T-cell: 2.3;memory CD4 T-cell: 2.5;NK-cell: 2.1" "Group enriched" "Detected in many" 12 "NK-cells: 2.1;T-cells: 2.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA026635 Uncertain "HPA026635: AB_1849266" "unprognostic (3.03e-2)" "unprognostic (6.88e-3)" "unprognostic (1.01e-1)" "unprognostic (1.01e-2)" "unprognostic (5.95e-2)" "unprognostic (5.34e-4)" "unprognostic (1.98e-2)" "unprognostic (6.36e-2)" "unprognostic (3.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.94e-3)" "unprognostic (1.88e-2)" "unprognostic (1.76e-1)" "unprognostic (3.23e-2)" "unprognostic (4.42e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" 1.5 0.7 4.3 0.4 2.6 0.4 1.2 0.4 11.5 0.6 0.9 0.3 0.4 0.5 0.4 0.6 0.3 0.5 0.5 0.5 2.3 1.3 0.3 0.4 1.2 1.0 0.6 8.0 0.3 13.4 3.8 1.0 0.6 0.2 0.7 0.7 1.4 0.3 1.1 0.4 1.0 0.6 0.4 0.2 0.8 2.1 0.6 0.0 0.0 0.3 0.0 0.7 0.6 0.3 0.2 0.0 0.0 0.0 2.1 2.5 0.2 0.0 0.0 0.1 0.0 3.8 1.7 0.1 1.2 0.3 0.1 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.5 0.0 1.4 0.0 0.1 0.3 0.0 0.5 0.0 0.6 0.0 2.0 1.4 0.0 1.2 1.6 0.0 0.0 0.0 0.0 0.3 0.0 0.1 2.0 1.2 3.1 0.0 0.6 0.0 0.9 6.7 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.5 0.0 2.3 0.2 2.5 0.0 0.0 0.0 1.0 0.2 0.0 2.1 0.0 0.0 0.0 0.2 4.3 2.6 0.4 11.5 2.3 1.3 0.6 8.0 0.2 0.0 GPR151 "GALR4, PGR7" ENSG00000173250 "G protein-coupled receptor 151" Q8TDV0 5 146513103-146516190 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "blood: 1.5;brain: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.5" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in single" 19 "thalamus: 36.8" "Region enriched" "Detected in single" 7 "thalamus: 4.6" HPA065728 Supported "HPA065728: " "unprognostic (2.09e-1)" "unprognostic (2.30e-1)" "unprognostic (1.14e-1)" "unprognostic (1.32e-2)" 0.0 0.1 0.4 0.0 0.5 0.1 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.4 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 GPR152 PGR5 ENSG00000175514 "G protein-coupled receptor 152" Q8TDT2 11 67451301-67452729 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.7;lymphoid tissue: 1.6" "Cell line enhanced" "Detected in single" "RPMI-8226: 3.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035078 Uncertain "HPA035078: AB_10670286" "unprognostic (3.81e-2)" "unprognostic (1.69e-1)" "unprognostic (2.70e-1)" "unprognostic (1.22e-1)" "unprognostic (3.76e-3)" 0.1 0.0 0.0 0.6 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 1.7 0.0 0.1 1.6 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.1 1.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.6 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.1 0.1 0.5 0.0 1.0 0.0 0.3 0.0 0.0 0.0 GPR153 PGR1 ENSG00000158292 "G protein-coupled receptor 153" Q6NV75 1 6247346-6260975 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 13.9;PC-3: 35.5;RH-30: 16.8;SCLC-21H: 17.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 4 "granulocytes: 1.3;monocytes: 1.0;T-cells: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007159 Approved "HPA007159: AB_1849268" "unprognostic (1.02e-2)" "unprognostic (2.40e-2)" "unprognostic (4.95e-2)" "prognostic unfavourable (3.07e-4)" "unprognostic (5.74e-3)" "unprognostic (3.33e-1)" "unprognostic (1.20e-1)" "prognostic unfavourable (3.75e-4)" "unprognostic (8.54e-2)" "unprognostic (1.02e-2)" "unprognostic (1.31e-1)" "unprognostic (1.51e-2)" "unprognostic (1.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.93e-1)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" 11.0 2.9 11.9 3.8 5.2 0.5 16.1 1.3 10.6 16.1 19.9 3.7 4.6 5.4 8.3 15.9 7.0 7.1 5.8 7.7 5.8 5.1 2.7 6.3 12.6 2.3 2.0 2.7 14.8 2.1 5.9 10.2 9.2 4.2 6.8 7.1 7.2 2.6 4.9 1.4 8.7 18.3 6.6 1.2 8.8 3.0 2.9 2.5 1.8 1.6 5.5 3.5 6.1 9.6 0.0 0.3 1.3 1.0 0.3 1.7 0.1 3.0 0.5 7.5 9.0 13.9 5.5 0.6 2.0 1.9 0.8 0.9 1.3 1.2 0.0 3.1 2.1 3.9 0.4 8.8 0.3 2.0 1.8 0.0 1.2 0.2 2.7 0.3 1.2 3.4 2.3 0.6 0.4 0.6 0.4 0.0 2.6 3.3 1.0 2.3 0.6 35.5 3.7 16.8 0.2 0.3 1.7 17.1 6.1 1.3 5.2 4.2 2.0 1.6 1.7 1.8 1.7 0.2 0.9 0.1 0.1 0.6 0.8 4.1 0.7 1.3 0.0 0.9 1.4 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.3 1.0 0.3 0.0 0.1 11.9 5.2 1.3 10.6 5.8 5.1 2.0 2.7 4.2 2.5 GPR156 "GABABL, PGR28" ENSG00000175697 "G protein-coupled receptor 156" Q8NFN8 3 120164645-120285094 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 7.7" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 3.0;PC-3: 3.0;SiHa: 7.9;U-2 OS: 4.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028642, HPA028644" Uncertain Supported "Plasma membrane" "Plasma membrane" "HPA028642: AB_10599711, HPA028644: AB_10600441" "unprognostic (2.85e-3)" "unprognostic (1.02e-1)" "unprognostic (3.53e-3)" "unprognostic (2.02e-3)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.62e-4)" "unprognostic (2.03e-1)" "unprognostic (4.54e-4)" "unprognostic (5.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (4.03e-5)" "unprognostic (2.43e-2)" "unprognostic (3.43e-2)" "unprognostic (4.91e-3)" "unprognostic (6.71e-2)" 0.9 0.5 0.8 1.6 2.2 0.0 1.0 0.1 1.0 1.4 0.7 0.0 0.0 0.0 1.2 0.0 1.9 3.4 1.3 0.2 0.4 0.3 0.3 0.0 0.2 0.0 0.3 0.0 1.4 0.0 0.0 1.4 1.2 0.7 1.9 0.2 0.4 2.4 1.5 0.1 0.3 0.2 1.6 1.5 0.1 0.3 7.7 1.2 0.0 0.1 0.0 0.4 2.5 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.2 0.8 0.1 0.9 1.3 0.1 0.6 0.0 0.8 3.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 2.0 0.0 0.8 0.2 0.0 1.9 0.2 0.4 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.9 3.0 0.0 0.0 0.0 0.0 0.0 1.0 1.5 7.9 0.0 0.9 1.0 0.1 0.2 0.2 4.4 0.0 0.3 1.0 0.4 0.1 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 2.2 0.1 1.0 0.4 0.3 0.3 0.0 0.7 1.2 GPR157 FLJ12132 ENSG00000180758 "G protein-coupled receptor 157" Q5UAW9 1 9100305-9129170 "G-protein coupled receptors, Predicted membrane proteins" Differentiation "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 32.2" "Cell line enhanced" "Detected in many" "Karpas-707: 16.9;SK-BR-3: 33.2;U-266/70: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA028697 Uncertain Uncertain "Nucleoli,Plasma membrane,Cell Junctions" Nucleoli "Plasma membrane, Cell Junctions" "HPA028697: AB_10601810" "unprognostic (2.83e-3)" "unprognostic (1.13e-2)" "unprognostic (5.91e-2)" "unprognostic (5.42e-2)" "unprognostic (2.13e-4)" "unprognostic (7.11e-2)" "unprognostic (7.52e-3)" "unprognostic (3.60e-2)" "unprognostic (9.20e-2)" "unprognostic (1.26e-1)" "unprognostic (9.13e-3)" "unprognostic (1.42e-1)" "unprognostic (1.02e-2)" "unprognostic (1.70e-2)" "unprognostic (1.21e-1)" "unprognostic (4.30e-2)" "unprognostic (3.04e-3)" 3.5 3.1 0.3 3.7 0.6 0.5 3.5 0.5 0.4 6.2 2.8 0.9 3.9 2.2 2.1 2.1 23.4 2.1 6.9 10.7 0.8 0.4 2.9 6.9 5.5 3.1 0.3 0.1 4.5 4.3 9.8 1.2 19.0 1.4 2.9 1.2 5.2 14.7 7.1 32.2 14.2 3.3 4.0 0.4 2.4 2.2 2.1 0.8 3.6 4.8 25.2 16.2 4.4 8.3 2.4 1.1 4.6 1.5 1.2 2.6 0.7 4.6 2.6 0.8 2.1 0.7 0.7 4.3 1.4 0.9 1.2 1.6 2.1 1.8 0.6 1.8 1.5 9.9 2.4 0.9 1.8 12.8 3.9 0.0 7.7 3.1 2.6 0.0 1.0 0.7 2.0 2.1 1.3 0.9 0.7 16.9 0.5 3.4 1.9 0.9 0.9 3.3 0.3 0.7 2.2 0.8 3.1 1.2 3.2 5.7 33.2 2.8 4.7 0.5 7.0 4.2 1.1 10.9 0.6 16.3 2.6 0.0 3.1 6.6 1.7 1.9 1.5 0.4 2.6 1.2 2.0 1.5 1.9 2.3 0.8 2.4 1.9 2.2 4.6 1.2 0.6 1.1 0.8 0.7 0.3 0.6 0.5 0.4 0.8 0.4 0.3 0.1 1.4 0.8 GPR158 KIAA1136 ENSG00000151025 "G protein-coupled receptor 158" Q5T848 10 25175062-25602226 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.4;seminal vesicle: 11.2" "Group enriched" "Detected in some" 5 "HEL: 20.7;T-47d: 5.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013185 Uncertain Approved Cytosol Cytosol "HPA013185: AB_2113957" "unprognostic (4.43e-2)" "unprognostic (3.14e-2)" "unprognostic (7.42e-2)" "unprognostic (2.66e-5)" "unprognostic (5.67e-2)" "unprognostic (9.37e-2)" "unprognostic (4.73e-2)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (8.09e-3)" "unprognostic (1.72e-1)" "unprognostic (2.60e-6)" "unprognostic (8.36e-2)" "unprognostic (1.78e-1)" "unprognostic (1.21e-3)" "unprognostic (3.90e-1)" 0.9 2.4 3.6 1.0 16.2 0.8 0.8 28.4 25.2 0.8 1.1 1.6 6.1 0.9 0.8 1.0 0.8 0.8 0.8 0.8 1.9 2.8 0.8 0.9 0.9 0.8 2.4 4.8 0.8 0.9 1.5 8.9 1.5 14.9 1.2 1.1 1.4 0.8 11.2 0.8 0.8 1.2 0.8 4.0 0.9 1.1 1.9 2.9 0.0 1.0 0.0 0.8 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 20.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.0 0.0 0.1 0.5 0.0 0.3 0.2 0.0 0.0 1.2 0.0 0.5 1.1 1.9 5.7 0.0 0.0 0.0 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 16.2 28.4 11.6 1.9 2.8 2.4 4.8 14.9 2.9 GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037929-170085403 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "parathyroid gland: 71.0" "Cell line enhanced" "Detected in many" "RPMI-8226: 30.4;SK-BR-3: 24.2;THP-1: 47.8;U-266/70: 52.8;U-266/84: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA006970 Approved Supported "Plasma membrane" "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favourable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favourable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favourable (3.61e-4)" 7.0 1.4 3.1 21.7 2.5 23.6 8.2 0.9 1.8 2.6 31.2 1.5 7.9 18.0 1.9 21.5 2.6 1.8 16.2 3.0 1.9 1.7 27.4 2.1 23.2 25.6 2.7 0.4 1.6 14.7 71.0 3.5 2.9 1.8 10.7 18.1 11.8 14.2 4.7 2.0 1.8 43.2 0.9 4.7 17.9 18.0 2.9 2.4 6.6 3.8 1.0 10.7 9.1 6.9 11.2 2.9 10.1 1.1 0.3 3.0 1.2 15.6 0.3 0.0 0.1 0.0 0.1 3.9 0.1 0.1 0.1 0.5 2.8 2.0 7.2 3.3 0.1 0.1 2.1 0.1 0.2 11.0 4.3 4.7 0.2 5.8 0.0 9.2 6.4 0.0 0.2 0.5 0.5 0.3 1.5 18.8 0.1 10.0 0.6 1.9 2.5 0.6 1.3 0.3 30.4 8.2 21.6 1.5 0.4 0.1 24.2 1.1 14.2 47.8 0.4 0.0 0.1 1.8 1.1 52.8 30.3 12.7 0.2 10.0 0.7 1.5 1.1 8.1 0.5 0.4 0.9 6.8 0.9 0.4 2.2 11.2 3.0 1.1 10.1 0.3 0.1 2.9 0.3 1.2 3.1 2.5 0.9 1.8 1.9 1.7 2.7 0.4 1.8 2.4 GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079543-168137667 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 27.1;smooth muscle: 21.0" "Cell line enhanced" "Detected in many" "CACO-2: 23.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Approved Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA015576: AB_1849283, HPA072047: " "unprognostic (1.45e-1)" "unprognostic (3.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (6.84e-2)" "unprognostic (3.24e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.04e-2)" "unprognostic (5.45e-2)" "unprognostic (1.31e-2)" "unprognostic (5.57e-6)" "unprognostic (3.93e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" 2.4 0.9 2.1 3.6 1.7 0.0 1.9 1.2 4.0 7.3 4.9 3.1 8.5 0.8 27.1 8.2 7.4 7.7 5.6 2.4 2.8 1.5 1.1 0.4 2.8 0.4 3.0 1.2 7.6 11.0 4.9 1.3 1.3 3.0 8.2 2.3 3.4 2.3 9.4 0.8 1.5 2.1 21.0 3.0 1.2 2.2 3.0 0.8 1.4 1.2 1.7 0.7 2.8 6.8 0.3 1.2 1.5 0.5 0.2 0.3 0.2 6.1 3.8 15.3 9.8 3.7 6.6 0.0 5.9 6.4 5.0 5.4 23.8 1.0 0.0 3.3 8.8 18.2 3.7 5.8 2.9 2.3 4.7 2.2 3.0 0.1 1.5 0.6 1.5 2.3 3.7 4.3 7.0 10.1 2.0 0.1 7.6 0.5 0.7 0.1 6.3 6.0 1.8 6.6 0.0 2.6 1.6 3.1 13.5 6.4 0.2 17.6 3.4 0.7 13.5 10.5 5.4 14.0 6.6 0.0 0.0 0.0 2.8 0.0 2.6 1.5 0.3 0.2 0.1 0.3 0.1 0.1 0.1 0.0 1.2 0.3 0.1 0.3 1.3 0.2 0.5 0.3 0.0 0.2 2.1 1.7 1.2 4.0 2.8 1.5 3.0 1.2 3.0 0.8 GPR162 "A-2, GRCA" ENSG00000250510 "G protein-coupled receptor 162" Q16538 12 6821545-6829972 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.6" "Cell line enhanced" "Detected in many" "AF22: 13.3;AN3-CA: 15.8;NTERA-2: 14.9;SH-SY5Y: 10.2;U-2 OS: 12.6" "Cancer enriched" "Detected in many" 6 "glioma: 16.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.3;intermediate monocyte: 3.7;neutrophil: 14.7" "Group enriched" "Detected in many" 6 "granulocytes: 14.7;monocytes: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055135 Enhanced Approved "Centriolar satellite" "Intracellular and membrane" "Centriolar satellite" "HPA055135: " "unprognostic (4.76e-2)" "unprognostic (8.00e-2)" "unprognostic (8.24e-3)" "unprognostic (1.31e-2)" "unprognostic (1.31e-1)" "unprognostic (2.38e-1)" "unprognostic (4.78e-2)" "unprognostic (2.25e-2)" "unprognostic (5.83e-3)" "unprognostic (1.18e-1)" "prognostic favourable (4.29e-5)" "unprognostic (3.82e-3)" "prognostic unfavourable (1.37e-6)" "unprognostic (3.10e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.64e-2)" 2.7 6.7 19.6 4.2 13.2 1.5 2.4 41.3 47.6 2.1 3.4 4.7 0.8 3.1 3.8 2.8 1.9 16.9 5.7 4.2 25.9 18.4 1.4 3.7 6.0 1.7 9.9 17.7 2.0 1.7 5.3 8.4 4.3 10.2 2.1 3.0 3.6 1.3 2.1 1.6 1.7 4.2 5.7 5.3 2.8 2.0 1.2 3.6 0.1 1.1 0.0 1.1 2.4 0.5 0.0 1.8 14.7 6.3 0.0 0.0 1.7 0.0 3.0 13.3 15.8 1.5 1.0 0.0 1.0 3.5 3.0 1.8 0.3 0.0 0.0 0.1 1.9 0.1 2.1 0.0 1.5 0.0 0.9 1.5 0.1 0.0 2.3 0.3 0.0 2.4 0.0 4.6 0.2 8.1 0.7 0.1 1.1 0.0 0.4 1.1 14.9 0.1 0.0 1.7 2.7 1.0 0.0 1.1 10.2 0.0 0.0 0.4 0.1 3.9 5.4 2.1 12.6 1.1 1.8 0.0 0.9 0.0 2.2 2.7 0.2 0.0 6.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 14.7 0.0 1.3 1.6 0.0 1.7 19.6 13.2 41.3 32.4 25.9 18.4 9.9 17.7 10.2 3.6 GPR17 ENSG00000144230 "G protein-coupled receptor 17" Q13304 2 127645864-127652639 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 43.8" "Cell line enhanced" "Detected in some" "HeLa: 4.5;REH: 7.5;TIME: 7.4;U-2 OS: 3.1;U-2197: 3.5;U-251 MG: 4.4" "Cancer enriched" "Detected in some" 32 "glioma: 16.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 11 "naive B-cell: 4.0" "Lineage enriched" "Detected in single" 11 "B-cells: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029766 Enhanced Supported Approved Vesicles Vesicles "HPA029766: AB_10612114" "unprognostic (8.10e-2)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (5.19e-2)" "unprognostic (2.77e-5)" "unprognostic (8.40e-3)" "unprognostic (2.92e-1)" "unprognostic (3.25e-2)" "unprognostic (1.61e-3)" "unprognostic (6.60e-2)" "unprognostic (2.11e-3)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" 7.0 2.2 23.7 6.8 21.3 0.8 5.4 4.1 25.6 2.4 16.4 43.8 0.0 3.3 11.2 3.3 5.0 4.0 4.3 12.5 20.6 1.2 2.3 1.6 9.3 2.4 9.1 9.9 1.4 4.6 0.5 0.4 2.7 18.8 3.9 0.8 0.1 1.7 0.5 13.1 6.7 3.8 0.5 6.3 12.6 5.0 1.8 22.6 0.0 2.8 0.0 0.5 6.1 3.9 4.0 0.3 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.6 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.5 0.8 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.0 0.0 0.6 0.2 0.1 0.2 7.5 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.3 0.0 7.4 0.0 3.1 3.5 4.4 0.2 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 4.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 23.7 21.3 4.1 25.6 20.6 1.2 9.1 9.9 18.8 22.6 GPR171 H963 ENSG00000174946 "G protein-coupled receptor 171" O14626 3 151197832-151203201 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 45.2;intestine: 19.5;lymphoid tissue: 33.0" "Cell line enriched" "Detected in single" 26 "U-266/70: 24.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "MAIT T-cell: 45.2" "Lineage enriched" "Detected in many" 18 "T-cells: 45.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062429 Approved "HPA062429: " "unprognostic (6.82e-6)" "unprognostic (4.90e-3)" "unprognostic (7.10e-2)" "unprognostic (6.85e-4)" "unprognostic (2.80e-3)" "unprognostic (1.04e-3)" "unprognostic (4.19e-4)" "unprognostic (6.09e-2)" "unprognostic (4.93e-3)" "unprognostic (1.01e-3)" "unprognostic (8.84e-2)" "unprognostic (1.08e-1)" "unprognostic (4.72e-6)" "unprognostic (1.31e-1)" "unprognostic (4.17e-2)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" 4.1 0.9 0.4 15.1 0.4 0.4 1.6 0.3 0.3 4.0 6.8 0.3 0.6 3.5 1.4 1.6 2.7 3.9 4.6 1.3 0.4 0.4 4.3 2.7 10.7 33.0 0.7 0.5 1.9 1.0 0.0 0.7 0.8 1.5 2.2 3.8 1.7 2.4 1.2 1.0 1.1 19.5 1.1 2.7 20.7 4.0 1.0 0.5 19.9 2.2 1.8 8.5 7.0 2.4 0.1 0.8 1.0 0.1 2.5 45.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.0 11.6 0.0 45.2 0.0 16.2 21.5 0.8 0.1 9.9 8.4 0.3 2.5 0.1 0.7 8.0 3.4 0.4 0.4 0.3 0.3 0.4 0.4 0.7 0.5 1.5 0.5 GPR173 SREB3 ENSG00000184194 "G protein-coupled receptor 173" Q9NS66 X 53049091-53080615 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 23.2" "Cell line enhanced" "Detected in many" "HAP1: 10.3" "Cancer enhanced" "Detected in many" "glioma: 8.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 5.7" "Group enriched" "Detected in many" 4 "granulocytes: 5.7;NK-cells: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003905 Approved "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA003905: AB_1078922" "unprognostic (2.68e-1)" "unprognostic (2.33e-1)" "unprognostic (4.95e-3)" "prognostic unfavourable (2.88e-6)" "unprognostic (3.87e-2)" "unprognostic (8.58e-2)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (1.92e-1)" "unprognostic (1.70e-2)" "prognostic favourable (2.33e-5)" "unprognostic (1.03e-1)" "prognostic unfavourable (2.47e-4)" "unprognostic (1.08e-4)" "unprognostic (2.83e-1)" "unprognostic (3.92e-2)" "unprognostic (6.95e-2)" 2.5 5.2 8.2 3.0 9.4 2.2 3.1 15.4 23.2 4.2 2.8 11.6 0.8 1.8 6.4 5.0 2.4 7.7 3.3 4.2 7.9 10.0 2.4 1.1 2.8 2.1 7.3 11.2 15.0 1.3 1.3 14.6 4.5 9.7 3.2 2.6 6.4 2.0 5.4 4.6 3.9 2.1 4.5 6.5 4.0 2.1 2.4 9.6 0.7 3.1 0.1 1.5 3.3 2.8 0.9 0.7 5.7 0.4 1.8 0.7 0.0 0.0 0.0 8.2 0.5 4.7 2.8 0.0 1.3 3.0 2.2 2.6 0.8 0.1 0.2 2.0 2.8 0.7 10.3 0.0 1.9 0.6 1.0 0.5 8.4 0.3 6.8 0.5 0.1 6.6 0.0 3.3 4.7 3.5 0.0 5.7 3.2 4.2 0.0 0.0 6.3 3.6 0.1 2.5 0.3 0.5 0.4 5.9 8.3 0.0 0.4 0.0 1.1 0.1 6.5 3.6 5.2 2.3 1.1 0.2 0.3 0.7 2.5 0.0 2.0 5.7 0.2 0.3 0.7 0.1 0.5 0.3 0.2 0.1 0.1 0.9 0.5 0.4 1.2 1.8 0.4 0.7 0.0 0.0 8.2 9.4 15.4 15.1 7.9 10.0 7.3 11.2 9.7 9.6 GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144663-79175315 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 73.8" "Cell line enriched" "Detected in some" 7 "MOLT-4: 41.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA041025 Enhanced Uncertain Vesicles Vesicles "HPA041025: AB_10794260" "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" 2.2 0.5 0.4 20.3 0.4 2.6 1.3 0.3 0.4 2.4 5.1 0.0 0.5 2.1 1.6 0.9 2.6 0.9 1.9 1.0 0.4 0.4 1.9 1.7 8.2 16.6 0.5 0.0 1.0 0.7 0.0 1.1 0.3 0.2 1.7 2.0 1.6 3.8 0.1 0.5 0.7 9.1 0.2 1.0 21.0 2.2 0.5 0.0 73.8 2.5 1.6 28.1 5.1 1.8 4.0 1.8 6.0 9.1 6.5 8.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 41.8 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.1 0.0 0.0 0.0 6.0 0.0 4.7 5.7 3.4 1.7 4.0 7.5 8.6 0.1 3.9 6.1 6.8 0.4 6.5 9.1 1.8 7.6 2.7 0.4 0.4 0.3 0.4 0.4 0.4 0.5 0.0 0.2 0.0 GPR176 Gm1012 ENSG00000166073 "G protein-coupled receptor 176" Q14439 15 39799032-39920892 "G-protein coupled receptors, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 68.5;fHDF/TERT166: 46.2;U-138 MG: 30.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "eosinophil: 2.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039943, HPA039979" Approved "HPA039943: AB_10697711, HPA039979: " "unprognostic (4.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (1.04e-2)" "unprognostic (2.75e-2)" "unprognostic (1.38e-3)" "unprognostic (9.32e-2)" "unprognostic (3.23e-2)" "unprognostic (2.74e-2)" "unprognostic (2.33e-2)" "prognostic unfavourable (9.38e-7)" "prognostic unfavourable (6.84e-5)" "unprognostic (2.23e-1)" "unprognostic (1.95e-1)" "unprognostic (3.26e-2)" 9.8 9.6 9.7 5.9 18.4 0.5 8.9 22.6 16.0 8.0 2.9 2.5 1.3 2.8 5.6 3.1 2.9 3.8 10.5 5.4 8.4 12.7 4.7 2.8 5.4 8.0 7.2 7.4 2.5 2.3 3.3 4.1 3.6 11.3 10.9 3.5 3.2 2.5 5.7 3.1 3.0 2.5 6.9 3.0 5.6 2.5 9.9 2.0 1.2 5.1 3.1 8.0 9.5 4.5 0.0 0.5 2.8 0.0 0.0 0.0 0.0 12.4 0.6 0.8 0.1 9.0 16.4 0.0 26.5 68.5 16.3 25.3 0.9 2.0 0.1 2.4 46.2 0.3 2.0 2.1 24.5 0.4 3.1 1.9 2.0 0.0 10.1 0.0 0.1 12.4 0.2 14.6 12.1 6.1 0.3 0.2 22.4 0.5 0.0 0.0 0.8 2.5 0.7 8.2 0.1 0.4 0.1 3.3 13.0 6.8 0.0 1.0 2.5 0.1 7.7 30.1 8.7 1.8 9.7 0.3 1.0 0.0 6.2 0.0 11.7 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 9.7 18.4 22.6 14.3 8.4 12.7 7.2 7.4 11.3 2.0 GPR18 ENSG00000125245 "G protein-coupled receptor 18" Q14330 13 99254714-99261744 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 25.4;lymphoid tissue: 25.1;testis: 15.0" "Group enriched" "Detected in some" 4 "Daudi: 8.4;THP-1: 19.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 25.4;NK-cells: 19.6;T-cells: 17.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013873 Enhanced "HPA013873: AB_1849285" "unprognostic (3.87e-6)" "unprognostic (1.31e-3)" "unprognostic (3.22e-2)" "unprognostic (1.31e-6)" "unprognostic (2.89e-1)" "unprognostic (7.55e-4)" "unprognostic (4.27e-5)" "unprognostic (3.45e-3)" "unprognostic (2.31e-3)" "unprognostic (5.43e-2)" "unprognostic (9.70e-2)" "unprognostic (4.03e-1)" "unprognostic (3.20e-6)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (6.92e-3)" 0.7 0.3 0.3 13.2 0.3 6.0 0.4 0.3 0.2 0.5 1.2 0.0 0.0 0.4 0.4 0.4 0.8 0.3 0.7 0.6 0.3 0.3 0.6 0.9 1.9 25.1 0.3 0.0 0.4 0.4 0.0 0.5 0.5 0.4 1.0 0.5 0.2 2.8 0.0 0.3 0.5 5.3 0.0 0.5 24.0 0.8 15.0 0.0 14.4 0.7 0.3 20.6 4.0 0.7 25.4 4.8 0.9 2.0 19.6 17.6 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 1.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 19.8 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 3.3 0.0 0.1 0.7 0.2 10.0 2.0 16.9 25.4 9.0 13.8 4.7 21.4 17.6 15.6 0.9 19.6 1.9 4.8 2.3 5.0 0.3 0.3 0.3 0.2 0.3 0.3 0.3 0.0 0.4 0.0 GPR182 "ADMR, AM-R, G10D, hrhAMR" ENSG00000166856 "G protein-coupled receptor 182" O15218 12 56994446-56998441 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "liver: 9.5;lymphoid tissue: 29.1;testis: 12.9" "Cell line enhanced" "Detected in some" "A549: 2.2;RH-30: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027037 Enhanced "HPA027037: AB_1844622" "unprognostic (6.13e-2)" "unprognostic (6.23e-2)" "unprognostic (3.56e-2)" "unprognostic (5.88e-2)" "unprognostic (2.60e-2)" "unprognostic (3.30e-1)" "unprognostic (2.10e-4)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (4.94e-1)" "unprognostic (1.67e-2)" "unprognostic (8.13e-2)" "unprognostic (5.62e-3)" "unprognostic (9.31e-2)" "unprognostic (2.88e-2)" "unprognostic (1.42e-1)" "unprognostic (4.34e-3)" 0.4 3.2 0.0 0.8 0.0 0.0 0.6 0.1 0.3 0.7 0.4 0.0 0.6 0.0 1.2 0.7 1.3 0.7 0.1 0.3 0.0 0.0 1.3 9.5 1.9 7.5 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.6 0.1 0.1 0.3 0.3 0.7 0.0 29.1 0.2 12.9 0.0 0.2 1.4 0.3 0.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.2 0.5 1.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.0 1.3 1.0 0.7 0.0 0.0 0.3 6.2 0.0 0.0 0.6 0.1 0.5 0.0 0.2 0.0 0.4 0.0 0.0 0.1 0.4 0.3 0.0 0.4 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 GPR183 EBI2 ENSG00000169508 "G protein-coupled receptor 183" P32249 13 99294530-99307405 "G-protein coupled receptors, Predicted membrane proteins" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 101.7" "Group enriched" "Detected in some" 47 "HDLM-2: 52.5;HL-60: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028847, CAB033690" Uncertain Approved "Nuclear membrane,Vesicles" "Nuclear membrane, Vesicles" "CAB033690: AB_2114269, HPA028847: AB_10603672" "unprognostic (3.28e-3)" "prognostic favourable (9.77e-4)" "unprognostic (6.03e-2)" "unprognostic (4.61e-3)" "unprognostic (3.45e-1)" "unprognostic (7.11e-2)" "unprognostic (1.71e-1)" "unprognostic (6.29e-2)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (5.75e-2)" "unprognostic (2.33e-1)" "unprognostic (4.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.97e-3)" "unprognostic (9.31e-3)" "unprognostic (9.86e-3)" 27.0 5.5 3.1 33.8 5.0 40.8 7.6 1.1 2.9 5.9 11.2 7.5 4.5 3.2 3.8 9.2 9.3 6.4 17.3 11.7 4.8 6.1 5.4 7.2 26.5 53.7 7.5 2.6 4.4 2.1 2.1 4.8 11.1 9.3 7.4 9.2 4.8 6.6 2.0 4.1 5.3 19.2 9.0 31.3 46.5 6.0 3.7 7.4 13.2 6.5 8.3 38.9 34.9 5.2 46.8 30.6 101.7 1.2 55.0 60.2 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 52.5 0.0 0.4 0.1 0.0 0.0 35.9 0.1 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 101.7 1.2 46.1 5.7 0.4 34.0 46.8 60.2 30.9 9.3 19.1 38.1 5.2 1.2 55.0 0.4 30.6 47.3 27.8 3.1 5.0 1.1 2.9 4.8 6.1 7.5 2.6 9.3 7.4 GPR19 ENSG00000183150 "G protein-coupled receptor 19" Q15760 12 12660891-12696207 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 9.2;brain: 13.3;pituitary gland: 9.8;testis: 9.8" "Cell line enhanced" "Detected in many" "HDLM-2: 23.2;NTERA-2: 24.1;WM-115: 12.3" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 9.2" "Group enriched" "Detected in many" 16 "granulocytes: 4.2;T-cells: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013955 Uncertain "HPA013955: AB_1849287" "unprognostic (1.92e-1)" "unprognostic (3.38e-2)" "unprognostic (1.72e-1)" "unprognostic (8.62e-5)" "unprognostic (1.60e-1)" "unprognostic (3.21e-1)" "unprognostic (8.25e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" "unprognostic (6.90e-2)" "unprognostic (1.45e-1)" "unprognostic (1.70e-2)" "unprognostic (2.67e-12)" "unprognostic (5.19e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (1.60e-1)" 1.0 2.4 7.5 4.8 13.3 2.3 1.2 11.5 13.0 0.8 1.5 2.8 0.0 1.1 0.7 0.7 1.5 1.0 1.1 0.7 8.5 8.4 0.7 0.8 0.8 4.3 5.6 6.3 0.5 1.1 1.0 9.8 1.1 3.7 0.5 1.9 0.4 0.6 0.6 0.4 2.2 1.1 1.1 6.7 1.7 1.3 9.8 3.6 0.3 0.7 0.0 5.8 1.3 0.2 0.3 0.0 4.2 0.0 0.4 9.2 0.5 0.9 0.3 10.0 0.2 0.0 0.0 4.3 0.9 1.0 1.8 1.5 3.9 6.0 4.0 1.5 0.7 0.8 1.6 0.2 2.9 23.2 0.2 0.9 0.4 0.6 0.0 1.0 0.4 0.0 0.0 1.9 1.1 0.3 0.1 8.3 0.3 1.4 0.3 0.5 24.1 1.8 2.6 1.5 0.1 0.1 0.8 3.3 3.0 0.4 0.9 7.7 0.5 1.0 0.0 0.5 4.5 0.8 2.3 4.6 4.0 7.7 1.9 2.8 12.3 0.0 0.0 0.0 1.8 0.0 1.4 0.3 3.8 2.1 0.0 0.1 0.7 1.4 4.2 0.4 0.0 0.0 9.2 0.5 7.5 13.3 11.5 10.6 8.5 8.4 5.6 6.3 3.7 3.6 GPR20 ENSG00000204882 "G protein-coupled receptor 20" Q99678 8 141356500-141367267 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "EFO-21: 6.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 12 "intermediate monocyte: 3.7;non-classical monocyte: 5.4" "Lineage enriched" "Detected in single" 14 "monocytes: 5.4" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.3" HPA071337 Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA071337: " "unprognostic (4.47e-2)" "unprognostic (2.64e-3)" "unprognostic (5.18e-2)" "unprognostic (2.00e-2)" "unprognostic (7.47e-2)" "unprognostic (2.28e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (3.54e-1)" "unprognostic (2.13e-2)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (7.41e-2)" "unprognostic (5.50e-2)" "unprognostic (6.23e-2)" "unprognostic (4.07e-1)" 2.8 0.5 0.7 2.7 1.4 0.1 2.5 0.2 2.0 10.6 9.1 1.0 4.3 2.2 6.7 1.9 3.4 3.9 6.1 2.1 0.8 0.4 1.1 0.4 3.5 0.3 1.4 0.9 3.7 0.5 0.5 0.5 3.2 2.1 2.2 1.0 1.1 0.5 3.0 2.1 1.0 10.5 4.5 0.5 0.8 4.3 1.6 0.7 0.0 1.4 1.5 0.5 1.7 3.4 0.0 0.3 0.3 5.4 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 6.9 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.5 0.5 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 5.4 0.0 0.0 0.1 0.7 1.4 0.2 2.0 0.8 0.4 1.4 0.9 2.1 0.7 GPR21 ENSG00000188394 "G protein-coupled receptor 21" Q99679 9 123034527-123035696 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 4.6" "Cell line enriched" "Detected in some" 8 "HBEC3-KT: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041651 Uncertain "HPA041651: AB_10794673" "unprognostic (9.22e-3)" "unprognostic (1.46e-1)" 3.6 0.0 1.1 1.7 2.2 0.2 1.1 0.1 4.6 2.1 0.4 0.0 2.7 1.0 1.9 0.9 0.8 0.5 0.7 0.4 0.3 0.0 0.5 1.9 0.3 1.4 0.0 0.2 0.0 1.5 0.1 0.6 0.1 0.7 0.4 0.6 0.3 1.7 0.4 0.9 0.5 0.0 1.0 0.9 1.3 2.0 0.9 0.0 0.1 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 8.2 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 GPR26 ENSG00000154478 "G protein-coupled receptor 26" Q8NDV2 10 123666355-123694607 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "brain: 8.6" "Cell line enriched" "Detected in single" 16 "SCLC-21H: 5.3" "Cancer enriched" "Detected in single" 13 "breast cancer: 0.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062736 Enhanced "HPA062736: " "unprognostic (4.15e-2)" "unprognostic (5.75e-2)" "unprognostic (3.42e-1)" "unprognostic (2.12e-1)" "unprognostic (9.09e-2)" "unprognostic (9.98e-2)" "unprognostic (2.12e-2)" "unprognostic (1.16e-2)" "unprognostic (1.12e-1)" 0.0 0.0 1.0 0.1 0.2 0.1 0.0 0.0 8.6 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.1 2.6 2.4 0.0 0.3 0.0 0.1 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 GPR27 SREB1 ENSG00000170837 "G protein-coupled receptor 27" Q9NS67 3 71754050-71756496 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 23.2;parathyroid gland: 29.6" "Cell line enhanced" "Detected in some" "EFO-21: 12.8;HL-60: 12.2;MCF7: 10.5;NTERA-2: 21.1;RPTEC TERT1: 10.1;SH-SY5Y: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "eosinophil: 3.7;neutrophil: 10.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029395 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA029395: AB_10602907" "prognostic favourable (5.63e-4)" "unprognostic (2.99e-1)" "unprognostic (3.23e-2)" "unprognostic (3.22e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-2)" "unprognostic (2.17e-2)" "unprognostic (1.18e-2)" "unprognostic (3.22e-1)" "prognostic favourable (1.21e-6)" "unprognostic (2.97e-3)" "unprognostic (4.97e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-2)" "unprognostic (2.71e-2)" "unprognostic (1.45e-2)" "unprognostic (6.79e-2)" 1.7 4.5 14.9 1.7 23.2 14.5 4.3 4.4 15.4 3.4 1.0 5.8 1.7 0.6 5.5 3.3 2.7 7.7 1.2 3.5 12.8 12.4 3.2 0.9 2.4 5.5 10.6 8.8 5.0 2.6 29.6 5.1 2.0 5.9 5.7 0.7 3.3 1.7 5.1 1.8 1.9 0.7 3.3 16.8 3.7 2.4 4.2 3.6 0.0 6.8 1.2 0.5 2.1 2.8 0.0 0.2 10.5 0.8 0.0 0.4 0.1 0.0 0.8 1.4 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 12.8 0.0 0.0 3.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 12.2 0.7 0.0 2.2 0.0 0.9 0.0 0.0 0.0 0.0 10.5 0.8 0.2 21.1 0.0 0.0 0.0 0.0 10.1 5.7 2.2 8.0 2.8 0.0 0.0 7.4 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.8 3.7 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.1 10.5 0.0 0.1 0.0 0.0 0.1 14.9 23.2 4.4 9.9 12.8 12.4 10.6 8.8 5.9 3.6 GPR3 ACCA ENSG00000181773 "G protein-coupled receptor 3" P46089 1 27392644-27395814 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.9" "Cell line enhanced" "Detected in many" "U-2197: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB006254 Uncertain "CAB006254: AB_425462" "unprognostic (4.42e-2)" "unprognostic (2.22e-1)" "unprognostic (4.05e-2)" "unprognostic (1.55e-2)" "unprognostic (1.38e-2)" "unprognostic (1.27e-1)" "unprognostic (7.30e-3)" "unprognostic (6.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.09e-1)" "unprognostic (5.94e-2)" "unprognostic (1.97e-1)" "unprognostic (1.46e-1)" "unprognostic (8.17e-2)" "unprognostic (2.07e-2)" "unprognostic (6.54e-2)" "unprognostic (1.03e-2)" 3.5 1.5 4.0 2.8 7.5 3.2 1.5 5.5 12.3 1.2 1.1 2.1 0.2 1.0 2.3 0.5 2.0 1.1 2.9 7.1 5.0 6.3 1.9 2.0 2.7 1.0 4.4 1.7 1.2 2.6 2.8 6.1 1.8 13.9 1.8 1.1 1.1 0.7 1.0 0.6 0.6 0.9 2.5 6.5 0.7 1.3 0.8 0.5 0.0 3.0 0.8 0.7 1.6 0.5 0.7 0.4 0.0 0.1 0.0 0.1 0.0 1.6 0.8 4.7 5.3 0.2 0.6 0.6 3.0 3.5 4.7 3.5 1.4 1.0 0.3 0.7 1.4 1.1 1.2 3.7 3.6 0.1 0.2 1.3 0.2 2.9 0.6 2.9 4.0 0.7 0.0 6.6 1.4 1.5 3.7 5.2 5.7 2.3 0.6 4.2 6.9 7.5 7.9 3.7 2.2 1.9 0.4 0.9 2.3 1.5 0.6 5.6 0.1 0.6 0.9 3.6 6.4 20.6 3.6 0.6 3.6 0.4 5.3 1.0 6.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.0 7.5 5.5 12.3 5.0 6.3 4.4 1.7 13.9 0.5 GPR31 "12-HETER, HETER1" ENSG00000120436 "G protein-coupled receptor 31" O00270 6 167156271-167158329 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 2.7;epididymis: 2.5;lymphoid tissue: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 28 "myeloid DC: 2.7" "Lineage enriched" "Detected in single" 28 "dendritic cells: 2.7" "Not detected" "Not detected" "HPA014014, HPA027108" Uncertain "HPA014014: AB_1849292, HPA027108: AB_10601474" "unprognostic (9.92e-2)" "unprognostic (1.52e-1)" "unprognostic (1.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.42e-3)" "unprognostic (2.20e-3)" "unprognostic (5.95e-3)" "unprognostic (4.03e-2)" "unprognostic (3.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (8.10e-4)" "unprognostic (2.45e-1)" "unprognostic (6.01e-2)" 0.0 0.0 0.1 0.9 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 2.5 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.1 4.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.9 0.0 0.2 2.1 0.3 1.1 0.1 1.4 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697277 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood: 60.8" "Cell line enhanced" "Detected in some" "HMC-1: 5.1;U-937: 1.4" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "basophil: 60.8;eosinophil: 25.3" "Lineage enriched" "Detected in many" 20 "granulocytes: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Uncertain Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" 25.1 12.4 15.1 9.7 16.6 0.4 15.0 2.1 11.7 10.5 9.1 13.5 1.0 4.4 4.9 6.6 5.8 5.5 12.2 5.9 16.0 9.5 11.7 5.3 11.4 26.8 22.4 7.5 5.4 4.4 2.8 3.3 29.3 15.4 5.7 9.3 4.9 7.1 6.4 2.1 2.4 11.4 11.5 34.0 22.3 5.1 5.0 21.4 1.9 3.4 1.5 11.1 12.5 3.7 0.3 0.4 60.8 2.8 3.0 0.1 0.5 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 1.0 0.4 0.0 0.2 0.0 0.1 5.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.8 0.3 0.5 0.1 1.1 0.0 0.3 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.1 0.8 0.1 0.0 0.0 0.1 0.6 1.4 0.0 60.8 2.2 25.3 0.0 2.8 0.0 0.3 0.1 0.0 0.4 0.1 0.0 0.0 0.2 3.0 1.5 0.0 0.1 0.5 15.1 16.6 2.1 11.7 16.0 9.5 22.4 7.5 15.4 21.4 GPR37 "EDNRBL, hET(B)R-LP, PAELR" ENSG00000170775 "G protein-coupled receptor 37" O15354 7 124745997-124765627 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 62.4" "Cell line enhanced" "Detected in many" "AF22: 9.4;fHDF/TERT166: 21.9;hTCEpi: 9.7;SK-BR-3: 8.5;TIME: 15.3" "Cancer enhanced" "Detected in many" "glioma: 19.2" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042903, HPA068009" Approved Approved "Nuclear membrane,Cytosol" 48000 "Nuclear membrane, Cytosol" "HPA042903: , HPA068009: " "unprognostic (2.47e-1)" "unprognostic (2.57e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-2)" "unprognostic (7.29e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavourable (6.00e-5)" "unprognostic (6.19e-2)" "prognostic favourable (7.26e-4)" "unprognostic (6.54e-2)" "unprognostic (2.58e-1)" "unprognostic (3.16e-2)" "unprognostic (6.12e-3)" "unprognostic (2.10e-1)" "unprognostic (1.88e-1)" "unprognostic (1.71e-4)" 1.6 1.0 14.5 1.1 19.6 0.9 1.7 2.3 52.6 1.5 1.4 62.4 0.0 1.0 2.1 1.4 7.8 2.1 1.4 0.9 23.9 11.3 1.2 8.8 1.3 1.1 33.5 12.3 1.0 3.0 0.8 0.3 10.0 23.3 1.8 1.5 3.5 1.6 1.8 1.1 4.1 1.3 3.0 49.4 4.3 1.2 15.5 26.5 0.0 0.9 0.0 0.9 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 9.4 0.0 0.0 0.0 2.7 0.5 2.5 2.4 0.6 0.4 0.8 0.0 0.0 21.9 0.2 2.7 0.0 0.5 0.4 1.2 0.1 5.9 0.0 2.8 0.0 0.4 0.0 9.7 0.0 0.1 4.5 0.0 4.3 0.0 0.5 0.0 0.0 1.4 4.5 0.0 0.0 0.0 0.0 0.1 2.2 3.3 0.0 8.5 3.2 2.2 0.0 15.3 2.0 0.7 0.0 0.0 1.3 0.0 0.0 1.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 19.6 2.3 19.6 23.9 11.3 33.5 12.3 23.3 26.5 GPR37L1 ETBR-LP-2 ENSG00000170075 "G protein-coupled receptor 37 like 1" O60883 1 202122858-202133592 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "brain: 44.0" "Group enriched" "Detected in some" 4 "HaCaT: 2.8;MCF7: 3.2;T-47d: 8.7" "Cancer enriched" "Detected in some" 57 "glioma: 36.2" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064454 Enhanced "HPA064454: " "unprognostic (2.12e-2)" "unprognostic (1.83e-1)" "unprognostic (2.96e-1)" "unprognostic (1.61e-3)" "unprognostic (4.52e-1)" "unprognostic (8.20e-2)" "unprognostic (2.26e-4)" "unprognostic (5.83e-2)" "unprognostic (3.46e-3)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (4.86e-3)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (1.18e-3)" "unprognostic (3.49e-1)" 1.6 2.0 20.5 1.6 25.2 1.9 1.6 13.2 44.0 2.0 2.4 33.4 0.0 1.9 1.8 1.8 1.7 1.8 1.7 1.6 22.3 12.6 1.5 1.6 1.6 1.5 17.7 22.1 1.7 1.5 1.5 0.4 1.6 23.8 1.7 1.9 0.9 1.9 2.3 1.7 1.8 2.1 1.7 11.1 1.6 1.6 1.9 15.7 0.0 1.8 0.0 1.5 1.6 0.2 0.9 0.9 1.8 0.9 0.6 1.4 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.2 0.6 0.0 0.1 0.0 2.8 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.1 1.2 0.0 8.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 1.0 0.8 0.7 0.5 0.9 0.7 0.6 0.3 0.2 0.6 0.9 0.7 0.5 1.8 0.6 0.4 0.9 1.4 0.2 20.5 25.2 13.2 39.3 22.3 12.6 17.7 22.1 23.8 15.7 GPR39 ENSG00000183840 "G protein-coupled receptor 39" O43194 2 132416574-132646559 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 22.0" "Cell line enhanced" "Detected in many" "A-431: 17.2;CAPAN-2: 14.7;hTEC/SVTERT24-B: 17.7;RT4: 15.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 6 "plasmacytoid DC: 4.3" "Lineage enriched" "Detected in single" 44 "dendritic cells: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA022111 Approved "HPA022111: AB_1849298" "unprognostic (4.06e-2)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (1.50e-2)" "unprognostic (5.19e-2)" "unprognostic (1.85e-1)" "unprognostic (8.54e-3)" "unprognostic (3.81e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "prognostic unfavourable (7.50e-4)" "unprognostic (2.28e-1)" "unprognostic (1.64e-1)" "unprognostic (3.72e-1)" "unprognostic (4.69e-2)" "unprognostic (1.25e-1)" "unprognostic (6.58e-3)" 0.5 0.1 0.6 4.9 1.1 0.0 2.2 0.4 0.3 4.8 14.4 0.1 3.5 4.7 3.2 1.8 1.5 3.4 10.0 0.7 0.5 0.5 8.7 8.6 9.3 0.0 0.6 0.0 1.4 22.0 14.1 0.4 1.3 0.6 3.0 6.0 1.6 1.3 8.7 0.1 1.0 14.4 0.8 0.3 0.1 6.5 0.8 0.0 0.6 4.1 0.0 1.0 6.5 1.9 0.0 4.3 0.0 0.0 0.0 0.0 0.0 17.2 8.2 0.1 0.0 0.3 2.3 0.0 1.2 6.2 3.3 1.9 9.4 14.7 0.0 3.3 1.0 8.2 0.0 7.1 3.2 0.0 0.0 0.0 0.9 0.3 0.3 0.0 0.0 0.6 5.4 17.7 1.7 0.0 0.0 0.0 2.3 1.4 0.0 0.0 0.1 5.3 0.0 0.2 0.0 11.3 15.5 0.0 0.1 1.0 5.8 0.0 3.3 0.0 3.0 7.1 5.3 1.5 5.2 0.0 0.0 0.0 8.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.6 1.1 0.4 0.3 0.5 0.5 0.6 0.0 0.6 0.0 GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602208 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "vagina: 32.0" "Group enriched" "Detected in some" 12 "HUVEC TERT2: 14.6;TIME: 24.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014278 Uncertain "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavourable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavourable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" 22.6 5.4 6.7 8.4 14.8 1.9 19.7 6.1 12.0 3.3 3.3 3.0 0.3 3.0 5.4 2.7 2.9 4.0 8.6 23.1 8.1 4.5 7.5 4.9 18.6 4.1 8.4 1.3 3.8 6.6 4.5 4.4 10.3 18.6 4.1 2.5 4.5 2.1 3.2 7.7 2.2 3.1 6.8 13.0 4.5 4.4 1.8 8.9 0.0 12.7 2.4 2.2 5.4 32.0 1.1 0.7 1.4 0.3 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 0.9 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.7 0.0 0.0 0.2 0.2 14.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.3 0.5 0.3 0.4 0.5 0.4 0.4 0.1 1.1 0.4 0.8 1.4 0.7 0.2 0.7 0.3 0.0 6.7 14.8 6.1 12.0 8.1 4.5 8.4 1.3 18.6 8.9 GPR42 "FFAR3L, GPR41L, GPR42P" ENSG00000126251 "G protein-coupled receptor 42 (gene/pseudogene)" O15529 19 35370929-35372962 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.3;blood: 2.1;intestine: 2.1" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "eosinophil: 1.9;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" HPA044681 Uncertain "HPA044681: " "unprognostic (1.73e-3)" "unprognostic (1.31e-4)" 2.3 0.0 0.0 1.5 0.1 0.1 1.2 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.1 1.3 0.1 0.4 0.1 0.3 0.0 0.0 0.0 0.0 2.1 0.2 0.4 0.8 1.3 0.0 0.5 0.0 0.3 0.0 0.0 0.1 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.9 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.0 GPR45 "PSP24, PSP24A" ENSG00000135973 "G protein-coupled receptor 45" Q9Y5Y3 2 105241743-105243049 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "brain: 5.7" "Group enriched" "Detected in some" 11 "BEWO: 3.1;U-2 OS: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055940 Uncertain "HPA055940: " "unprognostic (3.80e-3)" "unprognostic (5.92e-2)" "unprognostic (2.19e-3)" "unprognostic (4.71e-1)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (6.87e-2)" "unprognostic (2.21e-1)" "unprognostic (1.13e-1)" "unprognostic (3.96e-1)" "unprognostic (1.61e-3)" "unprognostic (1.11e-2)" "unprognostic (3.13e-4)" "unprognostic (2.25e-1)" "unprognostic (2.76e-1)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" 0.1 0.1 1.4 0.1 2.3 0.0 0.1 0.0 5.7 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.1 1.4 3.1 0.1 0.0 0.0 0.3 1.2 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.1 0.2 0.4 0.4 0.0 0.4 0.2 0.2 1.2 0.3 0.0 0.1 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 9.6 0.0 0.1 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR50 "H9, Mel1c" ENSG00000102195 "G protein-coupled receptor 50" Q13585 X 151176653-151181465 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "pituitary gland: 64.9" "Cell line enriched" "Detected in some" 8 "HEK 293: 10.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "hypothalamus: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "hypothalamus: 16.8" "Region enriched" "Detected in single" 9 "hypothalamus: 6.4" "HPA049862, HPA054678" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA049862: , HPA054678: " "unprognostic (8.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.15e-1)" 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.3 1.4 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 64.9 3.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.6 0.0 GPR61 BALGR ENSG00000156097 "G protein-coupled receptor 61" Q9BZJ8 1 109539872-109548406 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.6;pituitary gland: 6.3;retina: 6.3" "Cell line enhanced" "Detected in some" "Karpas-707: 1.1;U-266/70: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 1.1;naive CD8 T-cell: 1.0" "Group enriched" "Detected in many" 11 "granulocytes: 1.1;T-cells: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007326, HPA026088" Approved "HPA007326: AB_1849308, HPA026088: AB_10602323" "unprognostic (1.70e-1)" "unprognostic (1.61e-1)" "unprognostic (1.91e-1)" "unprognostic (2.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.70e-2)" "unprognostic (7.51e-2)" "unprognostic (3.63e-3)" "unprognostic (2.94e-2)" "unprognostic (4.50e-2)" "unprognostic (1.46e-4)" "unprognostic (3.27e-1)" "unprognostic (4.08e-4)" "unprognostic (1.33e-1)" "unprognostic (1.07e-1)" "unprognostic (6.72e-2)" "unprognostic (3.85e-2)" 0.5 4.0 4.9 0.7 8.2 0.7 0.5 6.4 10.6 0.5 0.6 0.2 0.0 0.8 0.8 0.6 0.7 0.5 0.7 0.9 5.4 3.9 0.6 0.6 0.5 0.8 1.7 8.3 0.6 0.5 0.5 6.3 0.6 4.9 0.6 0.5 6.3 0.7 0.5 2.3 0.8 1.0 0.5 1.2 0.6 0.6 1.7 1.2 0.0 3.6 0.0 0.5 0.7 0.3 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.4 0.5 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.4 0.2 0.3 0.2 0.2 0.3 0.3 0.0 0.0 0.1 0.6 0.1 0.2 0.0 0.1 0.1 0.0 0.2 0.2 0.4 0.5 0.0 2.4 0.4 0.2 0.0 0.3 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.1 0.0 4.9 8.2 6.4 10.6 5.4 3.9 1.7 8.3 4.9 1.2 GPR63 "PSP24(beta), PSP24B" ENSG00000112218 "G protein-coupled receptor 63" Q9BZJ6 6 96794126-96837463 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 7.8;HHSteC: 12.7;Karpas-707: 19.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039103 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039103: AB_10672841" "unprognostic (8.22e-2)" "unprognostic (2.77e-1)" "unprognostic (1.71e-2)" "unprognostic (1.02e-2)" "unprognostic (1.83e-1)" "unprognostic (1.33e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (3.39e-1)" "unprognostic (2.53e-2)" "unprognostic (7.29e-3)" "unprognostic (3.00e-1)" "unprognostic (2.03e-3)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-2)" 1.8 3.4 3.8 3.1 11.0 0.8 1.6 7.5 10.7 3.3 3.9 1.6 1.0 5.1 1.9 1.5 2.0 2.8 2.7 1.9 3.2 2.2 1.4 0.5 1.4 0.9 2.2 6.4 4.0 5.0 3.9 4.3 2.5 10.1 3.3 6.2 2.5 1.7 2.2 1.0 1.7 3.6 3.6 1.4 1.3 4.1 8.0 5.2 2.5 2.3 0.0 0.9 2.2 4.8 0.8 0.9 2.6 0.6 1.4 1.1 0.1 0.0 0.1 1.5 0.3 2.1 0.8 0.4 0.9 0.0 0.0 0.2 0.2 1.1 0.0 0.0 0.1 1.1 4.9 2.2 0.0 7.8 3.7 4.6 0.4 0.0 12.7 2.9 0.5 2.4 0.4 0.0 3.4 0.0 3.3 19.0 0.4 0.4 2.2 0.0 4.9 0.7 0.0 1.7 3.8 0.3 0.2 2.2 1.4 0.3 3.0 0.5 1.2 0.6 0.0 1.3 1.9 0.2 1.7 1.5 0.8 0.1 0.8 1.8 1.0 0.8 0.6 0.2 0.6 0.2 0.3 0.7 1.1 0.6 0.1 0.8 1.0 0.9 2.6 1.4 0.2 0.9 0.3 0.1 3.8 11.0 7.5 10.7 3.2 2.2 2.2 6.4 10.1 5.2 GPR65 "hTDAG8, TDAG8" ENSG00000140030 "G protein-coupled receptor 65" Q8IYL9 14 88005124-88014811 "G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 30.4;lymphoid tissue: 40.8" "Cell line enhanced" "Detected in some" "Daudi: 6.1;HEL: 6.6;HL-60: 7.9;HMC-1: 10.2;RH-30: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA072624, HPA077397" Enhanced Approved Nucleoli,Vesicles,Cytosol Vesicles "Nucleoli, Cytosol" "HPA072624: , HPA077397: " "unprognostic (8.56e-2)" "unprognostic (8.65e-3)" "unprognostic (1.98e-3)" "unprognostic (3.59e-3)" "unprognostic (3.10e-1)" "unprognostic (3.55e-3)" "unprognostic (1.15e-1)" "unprognostic (3.01e-2)" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "prognostic unfavourable (4.99e-4)" "unprognostic (3.79e-1)" "unprognostic (4.46e-3)" "unprognostic (9.03e-2)" "unprognostic (3.80e-1)" 9.8 3.1 1.8 12.1 6.4 15.2 2.3 0.7 3.0 1.9 2.4 0.9 0.9 2.3 2.2 2.2 2.3 2.2 4.1 2.3 6.0 2.1 4.0 6.9 10.6 13.1 8.2 0.0 1.7 1.8 0.8 6.2 3.6 6.3 2.9 2.3 1.2 2.6 0.9 0.9 1.2 7.7 3.3 15.7 40.8 2.5 1.5 6.2 12.5 1.8 2.3 8.9 4.8 2.3 4.3 5.9 19.1 13.7 21.3 30.4 9.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.6 0.0 0.0 0.3 7.9 10.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 1.1 0.0 0.0 0.2 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 14.6 9.1 19.1 16.5 12.8 30.4 4.3 8.4 12.6 5.9 4.0 4.4 9.7 6.9 21.3 13.7 2.7 4.0 9.4 1.8 6.4 0.7 3.0 6.0 2.1 8.2 0.0 6.3 6.2 GPR78 ENSG00000155269 "G protein-coupled receptor 78" Q96P69 4 8558725-8619761 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "placenta: 53.3" "Cell line enriched" "Detected in single" 202 "BEWO: 21.2" "Cancer enhanced" "Detected in single" "urothelial cancer: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA013209 Uncertain "HPA013209: AB_10601657" "unprognostic (6.41e-2)" "unprognostic (1.77e-2)" "unprognostic (1.17e-2)" "unprognostic (2.51e-1)" "unprognostic (1.81e-2)" "unprognostic (3.70e-2)" "unprognostic (3.82e-4)" "unprognostic (6.46e-3)" "unprognostic (1.20e-1)" "unprognostic (3.80e-2)" "unprognostic (2.29e-1)" "unprognostic (4.88e-15)" "unprognostic (5.55e-3)" "unprognostic (3.93e-2)" "unprognostic (9.90e-3)" "unprognostic (8.15e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 GPR82 ENSG00000171657 "G protein-coupled receptor 82" Q96P67 X 41724155-41730135 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood: 23.2;lymphoid tissue: 12.0" "Cell line enriched" "Detected in single" 16 "HMC-1: 9.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "eosinophil: 23.2;NK-cell: 6.6" "Group enriched" "Detected in many" 9 "granulocytes: 23.2;NK-cells: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035914 Approved "HPA035914: AB_10670671" "unprognostic (5.62e-3)" "unprognostic (1.81e-2)" "unprognostic (4.65e-2)" "unprognostic (3.88e-3)" "unprognostic (1.15e-2)" "unprognostic (3.28e-2)" "unprognostic (4.62e-4)" "unprognostic (1.41e-3)" "unprognostic (2.12e-2)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (7.45e-2)" "unprognostic (2.37e-2)" "unprognostic (2.26e-1)" "unprognostic (8.00e-3)" "unprognostic (1.18e-1)" 1.2 2.2 1.6 3.9 5.9 0.2 1.1 0.6 1.5 0.9 2.7 0.3 0.0 3.0 0.8 1.1 1.1 1.1 1.1 0.7 2.5 1.1 4.7 5.0 10.0 9.0 2.5 0.1 0.7 1.5 0.1 1.1 0.3 3.2 1.1 2.1 0.8 0.8 0.7 0.4 0.7 5.2 0.6 7.3 3.6 1.6 0.4 2.3 1.6 0.8 0.6 12.0 2.4 0.9 0.1 0.2 23.2 1.6 6.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.2 23.2 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 6.6 1.4 0.0 0.0 0.1 1.6 5.9 0.6 1.5 2.5 1.1 2.5 0.1 3.2 2.3 GPR84 EX33 ENSG00000139572 "G protein-coupled receptor 84" Q9NQS5 12 54362445-54364487 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2" "Group enriched" "Detected in some" 5 "HL-60: 9.1;NB-4: 28.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 23 "basophil: 6.0;classical monocyte: 8.7;myeloid DC: 12.9;neutrophil: 5.3" "Group enriched" "Detected in many" 53 "dendritic cells: 12.9;granulocytes: 6.0;monocytes: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA027603 Enhanced "HPA027603: AB_10612115" "unprognostic (5.40e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (3.92e-2)" "unprognostic (2.36e-2)" "unprognostic (4.54e-2)" "unprognostic (6.16e-3)" "unprognostic (7.43e-2)" "unprognostic (9.29e-2)" "unprognostic (1.37e-1)" "unprognostic (2.34e-2)" "unprognostic (2.92e-1)" "unprognostic (1.36e-9)" "unprognostic (1.27e-1)" "unprognostic (4.42e-2)" "unprognostic (1.40e-1)" "unprognostic (9.44e-2)" 7.2 2.3 2.7 11.2 6.8 27.2 0.7 0.4 3.3 1.0 0.9 5.0 0.0 0.8 0.6 0.9 1.1 1.7 1.8 3.2 1.6 2.1 2.4 0.8 5.3 2.7 4.4 0.0 2.7 1.0 0.7 2.3 6.7 5.0 1.2 1.3 0.7 1.2 0.7 1.1 1.4 0.8 2.8 6.7 8.0 1.2 2.1 7.5 0.9 2.1 0.0 2.8 3.0 2.1 0.0 12.9 6.0 8.7 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.1 1.6 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.7 0.0 6.0 8.7 0.0 0.0 0.3 0.0 0.0 0.0 0.1 12.9 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 1.8 2.7 6.8 0.4 3.3 1.6 2.1 4.4 0.0 5.0 7.5 GPR87 GPR95 ENSG00000138271 "G protein-coupled receptor 87" Q9BY21 3 151294086-151316952 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 24.8;skin 1: 19.7;tongue: 21.9" "Cell line enhanced" "Detected in some" "A-431: 30.8;HaCaT: 24.6;HBEC3-KT: 32.8;hTCEpi: 43.8;hTERT-HME1: 18.4;RT4: 12.9" "Group enriched" "Detected in many" 6 "cervical cancer: 44.1;head and neck cancer: 40.1;lung cancer: 22.0;urothelial cancer: 23.3" "Region enriched" "Detected in single" 12 "pons and medulla: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066313 Approved "Nucleoplasm,Lipid droplets,Mitochondria" "Lipid droplets, Mitochondria" Nucleoplasm "HPA066313: " "unprognostic (5.81e-2)" "unprognostic (2.12e-1)" "unprognostic (4.07e-3)" "unprognostic (8.60e-2)" "unprognostic (1.28e-2)" "unprognostic (4.61e-3)" "unprognostic (3.28e-2)" "unprognostic (1.27e-1)" "prognostic unfavourable (4.62e-6)" "unprognostic (8.64e-2)" "unprognostic (1.50e-3)" "unprognostic (3.66e-4)" "unprognostic (8.73e-2)" "unprognostic (3.80e-2)" "unprognostic (2.17e-1)" 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.4 6.5 0.0 0.0 2.8 0.0 0.4 2.1 24.8 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.6 11.1 5.1 4.5 0.0 0.0 9.5 4.0 0.0 19.7 0.0 0.4 0.0 0.0 0.2 0.7 0.0 2.0 0.0 21.9 13.5 6.2 13.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.2 0.0 0.0 11.3 0.0 0.0 0.0 24.6 0.0 32.8 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 43.8 0.0 18.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.7 0.0 0.0 0.0 1.1 12.9 0.0 0.0 5.4 0.1 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 5.1 0.0 GPR88 ENSG00000181656 "G protein-coupled receptor 88" Q9GZN0 1 100538137-100542018 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Mental retardation" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 62.7" "Group enriched" "Detected in some" 8 "HSkMC: 4.8;SCLC-21H: 5.9" "Cancer enriched" "Detected in some" 9 "liver cancer: 12.0" "Group enriched" "Detected in many" 7 "basal ganglia: 62.7;thalamus: 32.8" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 11 "basal ganglia: 643.5" "Region enriched" "Detected in some" 35 "basal ganglia: 223.4" HPA007488 Approved "HPA007488: " "unprognostic (1.65e-1)" "unprognostic (1.50e-1)" "unprognostic (8.30e-2)" "unprognostic (8.37e-3)" "unprognostic (5.41e-1)" "unprognostic (5.63e-2)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (1.03e-2)" "unprognostic (7.76e-2)" "unprognostic (8.23e-3)" "unprognostic (2.45e-1)" "unprognostic (3.93e-4)" "unprognostic (1.85e-2)" "unprognostic (5.56e-2)" "unprognostic (4.41e-1)" "unprognostic (1.35e-2)" 0.7 0.6 1.2 0.5 62.7 0.2 10.9 0.0 6.8 0.1 0.3 0.8 0.0 0.6 0.2 0.2 0.2 0.1 0.2 0.4 0.9 0.8 0.3 13.1 0.2 0.3 0.7 1.1 3.8 0.1 4.6 0.5 0.2 7.0 0.6 0.5 0.3 0.7 0.1 0.3 0.1 0.5 0.3 0.5 13.7 0.4 0.2 32.8 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 62.7 0.0 6.8 0.9 0.8 0.7 1.1 7.0 32.8 GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12890782-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 155.0" "Cell line enhanced" "Detected in many" "A-431: 41.8;CAPAN-2: 161.0;HaCaT: 42.2;SiHa: 59.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "pons and medulla: 3.1" "Cell type enhanced" "Detected in some" "basophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA007928, HPA046526" Enhanced Enhanced "Vesicles,Plasma membrane" "Vesicles, Plasma membrane" "HPA007928: AB_1849318, HPA046526: " "unprognostic (4.79e-2)" "unprognostic (8.35e-2)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (4.65e-3)" "unprognostic (1.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.89e-2)" "unprognostic (3.48e-1)" "unprognostic (8.69e-3)" "prognostic unfavourable (4.63e-6)" "unprognostic (3.81e-1)" "prognostic unfavourable (9.02e-5)" "unprognostic (9.30e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-2)" "unprognostic (2.49e-1)" 9.8 1.4 0.2 6.0 0.6 0.4 5.4 0.1 0.3 12.1 19.8 0.5 2.0 6.2 4.3 1.9 9.1 3.0 15.5 7.1 0.1 0.2 5.1 0.6 155.0 0.1 0.5 0.1 18.5 1.1 0.0 0.9 20.1 3.1 10.4 16.9 4.8 9.6 1.5 1.1 2.0 36.9 14.2 1.1 0.1 11.4 4.8 0.3 0.1 54.2 14.9 11.5 32.1 14.0 0.6 0.6 3.1 0.3 0.5 0.4 0.0 41.8 33.5 0.0 0.1 0.4 0.2 2.1 12.6 4.8 8.2 6.3 5.8 161.0 0.0 1.0 10.0 42.2 0.1 6.1 12.6 0.0 0.5 0.0 13.8 0.2 3.0 0.0 0.0 0.2 8.2 3.4 0.8 5.0 0.0 0.0 0.3 29.3 0.0 0.0 0.1 5.2 0.0 0.9 0.0 16.3 8.3 0.0 0.0 59.2 4.5 1.9 1.3 0.1 0.5 0.3 10.7 19.2 0.5 0.0 0.0 0.0 4.3 0.0 0.2 3.1 0.3 0.4 0.3 0.2 0.3 0.3 0.2 0.3 0.1 0.6 0.4 0.4 1.3 0.5 0.2 0.6 0.3 0.0 0.2 0.6 0.1 0.3 0.1 0.2 0.5 0.1 3.1 0.3 GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 108.0" "Cell line enhanced" "Detected in many" "EFO-21: 38.4;HHSteC: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "naive CD4 T-cell: 6.5" "Lineage enriched" "Detected in many" 4 "T-cells: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavourable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favourable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" 12.6 4.4 45.2 3.2 55.9 1.0 7.3 22.8 108.0 5.4 2.9 95.1 4.9 4.0 7.1 9.3 5.5 12.7 9.2 22.3 47.8 28.7 12.1 2.7 3.9 4.6 63.1 34.9 13.7 12.7 9.5 3.8 9.3 38.6 6.3 2.3 3.8 20.8 11.5 35.1 2.5 3.3 5.1 61.6 2.2 22.7 19.6 63.1 0.0 7.2 2.6 2.7 6.2 3.0 0.0 0.0 0.0 1.5 0.0 6.5 1.3 0.4 12.3 12.3 2.2 12.7 0.8 2.2 0.1 3.1 1.2 0.8 11.3 0.4 0.0 38.4 0.4 0.6 9.0 0.0 0.7 0.0 3.3 0.0 0.0 0.0 26.2 0.0 0.0 1.1 0.0 2.1 0.0 6.0 2.5 0.2 2.8 0.6 0.0 0.0 13.4 5.8 3.5 0.0 0.0 0.4 5.7 9.5 0.8 1.4 0.8 11.0 0.0 0.2 1.1 0.0 1.4 6.0 0.3 0.1 0.0 0.0 0.6 0.1 0.7 0.0 0.1 0.0 0.0 1.5 0.0 0.0 1.6 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.3 0.0 0.0 1.3 45.2 55.9 22.8 40.5 47.8 28.7 63.1 34.9 38.6 63.1 GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 76.2" "Cell line enhanced" "Detected in many" "Hep G2: 23.9;HMC-1: 42.1;RPTEC TERT1: 56.7;RT4: 26.2;T-47d: 31.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 31.1" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 10.2" "Group enriched" "Detected in many" 9 "dendritic cells: 10.2;monocytes: 4.7" "Region enriched" "Detected in many" 9 "cerebellum: 47.7" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favourable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" 4.3 4.1 5.2 2.2 5.3 0.0 7.7 31.1 5.7 19.7 15.4 4.4 17.0 10.0 5.8 9.9 5.3 12.5 17.6 7.7 5.3 2.6 43.8 46.1 11.5 2.8 4.8 4.9 12.3 76.2 12.0 3.4 4.5 6.1 15.1 6.2 18.0 16.8 11.7 25.4 9.2 15.2 3.9 4.6 5.1 44.7 4.4 4.1 1.9 42.2 10.2 3.5 12.6 8.0 0.7 10.2 0.1 4.7 0.0 0.1 0.3 4.6 16.6 1.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.2 21.4 0.0 13.2 0.1 14.7 2.2 0.3 0.0 0.0 2.7 0.0 1.2 23.9 4.9 0.0 42.1 0.4 7.6 0.0 0.0 0.0 1.2 0.3 0.0 5.2 0.1 4.5 2.7 19.4 0.0 0.0 1.0 56.7 26.2 8.0 0.7 0.8 1.8 0.0 31.9 1.2 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 2.0 0.6 0.1 0.0 1.7 0.1 0.0 3.4 0.0 0.7 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 4.7 10.2 0.0 0.3 5.2 5.3 31.1 5.7 5.3 2.6 4.8 4.9 6.1 4.1 GPRC5D ENSG00000111291 "G protein-coupled receptor class C group 5 member D" Q9NZD1 12 12940775-12952147 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 18.4;skin 1: 33.9" "Group enriched" "Detected in some" 10 "Karpas-707: 36.6;RPMI-8226: 35.5;U-266/84: 10.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "pons and medulla: 2.1" "Cell type enriched" "Detected in some" 4 "memory B-cell: 18.4" "Lineage enriched" "Detected in many" 17 "B-cells: 18.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA071909 Approved "HPA071909: " "unprognostic (4.27e-2)" "unprognostic (8.58e-2)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (4.34e-2)" "prognostic favourable (5.09e-4)" "unprognostic (3.00e-5)" "unprognostic (4.06e-2)" "unprognostic (3.06e-2)" "unprognostic (5.53e-2)" "unprognostic (7.01e-2)" "unprognostic (2.27e-2)" "unprognostic (8.33e-3)" "unprognostic (9.54e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-2)" "unprognostic (6.63e-2)" 1.0 0.5 0.4 3.1 0.4 0.3 4.2 0.4 0.4 0.8 3.8 0.4 0.4 2.4 1.0 0.4 3.7 0.3 1.5 0.7 0.4 0.2 0.8 0.7 4.4 5.9 0.4 0.4 0.4 2.9 0.0 1.0 0.9 2.1 0.9 3.4 0.7 8.6 0.4 0.4 33.9 3.8 0.4 0.4 5.1 3.3 3.7 0.4 0.4 1.3 5.2 4.1 1.3 0.7 18.4 0.1 1.0 0.0 0.0 0.2 1.9 0.5 0.6 0.0 0.6 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.5 1.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.7 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 36.6 0.1 1.2 0.0 0.0 0.3 0.0 0.0 0.0 35.5 0.0 1.4 1.1 0.2 0.8 0.6 0.0 0.0 0.0 1.0 0.0 1.7 0.0 0.0 1.9 10.0 0.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 18.4 0.1 0.0 0.1 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.4 0.4 0.4 0.4 0.4 0.2 0.4 0.4 2.1 0.4 GRM1 "GPRC1A, mGlu1, MGLUR1, PPP1R85" ENSG00000152822 "Glutamate metabotropic receptor 1" Q13255 6 146027646-146437598 "Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 39.9" "Cell line enhanced" "Detected in some" "AF22: 1.6;HeLa: 1.4;Karpas-707: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 39.9" "Cell type enriched" "Detected in single" 4 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015701 Approved Supported Approved Vesicles Vesicles "HPA015701: AB_1853917" "unprognostic (1.04e-2)" "unprognostic (7.33e-2)" "unprognostic (3.73e-3)" "unprognostic (9.77e-3)" "unprognostic (6.75e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-2)" "unprognostic (4.31e-2)" "unprognostic (2.93e-2)" "unprognostic (9.48e-3)" "unprognostic (7.92e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (8.33e-3)" "unprognostic (9.76e-2)" 0.5 0.5 6.6 0.4 6.0 0.4 0.5 39.9 13.0 0.5 0.5 0.9 0.0 0.4 0.5 0.7 0.5 0.7 0.5 7.7 6.0 2.7 2.7 0.5 0.6 0.5 2.6 4.1 0.5 0.5 0.4 0.2 0.5 3.6 0.5 0.4 2.6 0.5 0.8 0.4 0.5 0.5 0.5 1.0 0.6 0.5 1.3 0.9 0.0 0.8 0.0 0.4 0.5 0.1 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.1 1.6 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.4 1.4 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 1.5 0.1 0.0 0.0 0.4 0.2 0.8 0.0 0.0 0.0 0.1 0.0 1.1 0.6 0.1 0.1 0.5 0.0 0.5 0.1 0.1 0.1 0.7 0.2 0.2 0.1 0.1 0.5 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 6.6 6.0 39.9 10.5 6.0 2.7 2.6 4.1 3.6 0.9 GRM2 "GPRC1B, mGlu2, MGLUR2" ENSG00000164082 "Glutamate metabotropic receptor 2" Q14416 3 51707070-51718613 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 13.2" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 11.7" "Cancer enhanced" "Detected in single" "testis cancer: 1.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027868, HPA065166" Approved Supported "HPA027868: , HPA065166: " "unprognostic (1.01e-1)" "unprognostic (8.61e-4)" "unprognostic (7.66e-2)" "unprognostic (7.29e-3)" "unprognostic (1.98e-1)" "unprognostic (3.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.27e-1)" "unprognostic (1.39e-2)" "unprognostic (2.05e-1)" "unprognostic (4.45e-1)" "unprognostic (1.74e-1)" "unprognostic (1.37e-2)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (2.93e-2)" "unprognostic (1.19e-2)" 0.8 0.6 4.6 0.8 6.3 1.6 0.7 3.8 13.2 0.6 0.6 0.4 0.0 0.6 0.8 0.4 0.5 0.5 0.4 0.9 3.0 3.1 0.5 0.5 0.6 0.7 1.2 7.0 0.5 0.4 0.4 0.4 0.6 8.3 0.7 0.5 0.6 0.8 0.6 1.8 1.3 0.5 0.6 0.5 1.1 0.5 1.3 0.2 0.0 0.5 0.0 0.5 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 6.3 3.8 13.2 3.0 3.1 1.2 7.0 8.3 0.2 GRM4 "GPRC1D, mGlu4, MGLUR4" ENSG00000124493 "Glutamate metabotropic receptor 4" Q14833 6 34018645-34155622 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "brain: 101.6" "Group enriched" "Detected in some" 8 "BEWO: 6.4;SCLC-21H: 25.4" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Region enriched" "Detected in many" 21 "cerebellum: 101.6" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in all" "cerebellum: 83.5" "Region enriched" "Detected in many" 4 "cerebellum: 252.6" CAB022096 Enhanced "CAB022096: " "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.03e-1)" "unprognostic (7.00e-2)" "unprognostic (4.03e-2)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (3.56e-1)" "unprognostic (9.45e-2)" "unprognostic (2.08e-2)" "unprognostic (6.21e-3)" "unprognostic (2.44e-1)" "unprognostic (2.15e-11)" "unprognostic (5.32e-2)" "unprognostic (9.16e-2)" "unprognostic (6.57e-2)" "unprognostic (3.07e-1)" 0.2 0.1 0.4 0.3 4.9 0.2 0.2 101.6 7.2 0.6 0.1 0.3 0.1 0.5 0.5 0.1 0.1 0.3 0.1 0.1 0.5 0.9 0.2 0.3 0.3 0.2 0.3 0.4 0.2 3.5 0.1 0.0 0.3 4.3 0.3 0.2 0.1 0.1 0.2 0.3 0.6 0.8 0.7 1.1 0.1 0.2 1.6 0.5 0.0 0.3 0.0 0.7 0.4 0.0 0.2 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 25.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 4.9 101.6 1.0 0.5 0.9 0.3 0.4 4.3 0.5 GRM6 "CSNB1B, GPRC1F, mGlu6, MGLUR6" ENSG00000113262 "Glutamate metabotropic receptor 6" O15303 5 178978327-178996206 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Receptor, Transducer" "Congenital stationary night blindness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 22.0" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA014511 Enhanced "HPA014511: " "unprognostic (1.85e-1)" "unprognostic (1.54e-1)" "unprognostic (8.41e-2)" "unprognostic (1.27e-1)" "unprognostic (4.16e-1)" "unprognostic (2.25e-3)" "unprognostic (7.72e-2)" "unprognostic (2.32e-2)" "unprognostic (2.12e-3)" "unprognostic (6.27e-2)" "unprognostic (3.34e-4)" "unprognostic (2.58e-1)" "unprognostic (3.36e-4)" "unprognostic (1.23e-1)" "unprognostic (6.45e-2)" "unprognostic (7.59e-3)" "unprognostic (1.97e-1)" 0.3 0.5 0.6 0.4 0.6 1.6 0.3 1.9 1.6 0.4 0.4 0.3 0.3 0.3 0.6 0.5 0.3 0.5 0.7 0.4 0.5 1.2 0.4 0.4 0.4 0.5 0.8 0.3 0.7 0.9 0.1 2.9 0.3 1.2 1.1 0.1 22.0 0.6 0.3 1.3 1.8 0.3 0.3 0.3 0.5 0.3 2.2 0.3 0.3 0.9 0.3 0.3 0.3 0.3 0.9 1.1 2.4 0.4 0.6 0.6 0.1 0.5 0.3 0.7 1.3 0.3 0.1 0.7 0.2 0.0 0.1 0.0 0.5 0.9 0.8 0.6 0.0 0.7 0.0 0.1 0.0 0.2 0.7 0.5 0.7 1.0 0.2 0.8 0.9 0.1 0.3 0.1 0.5 0.0 0.9 1.7 0.0 1.0 0.2 0.7 0.6 0.6 0.6 0.3 0.8 0.1 0.6 0.9 1.2 0.5 0.7 0.5 0.9 1.1 0.9 0.5 0.5 0.4 0.5 0.7 0.6 0.4 0.4 0.7 0.3 1.9 0.4 0.5 0.6 0.3 0.4 0.4 0.4 0.3 0.2 0.9 0.4 0.4 2.4 0.6 0.2 1.1 0.2 0.1 0.6 0.6 1.9 0.5 0.5 1.2 0.8 0.3 1.2 0.3 GRM7 "GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87" ENSG00000196277 "Glutamate metabotropic receptor 7" Q14831 3 6770001-7741533 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.8;parathyroid gland: 11.3" "Cell line enriched" "Detected in single" 11 "SH-SY5Y: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015964 Uncertain Cytosol Cytosol "HPA015964: " "unprognostic (2.04e-2)" "unprognostic (7.03e-3)" "unprognostic (1.43e-1)" "unprognostic (9.37e-2)" "unprognostic (8.48e-3)" "unprognostic (2.58e-1)" "unprognostic (7.30e-2)" "unprognostic (3.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.46e-2)" "unprognostic (2.54e-1)" "unprognostic (6.84e-6)" "unprognostic (1.45e-1)" "unprognostic (2.82e-2)" "unprognostic (5.43e-2)" "unprognostic (2.59e-2)" 0.9 5.3 8.1 0.6 10.5 0.6 0.9 1.6 15.8 2.9 0.8 2.1 0.0 0.9 3.1 0.5 0.6 1.0 0.7 0.6 11.1 9.3 0.5 0.7 0.8 0.5 2.3 10.1 0.8 0.7 11.3 0.6 0.9 4.3 1.2 0.8 0.8 2.1 1.4 0.5 0.6 0.6 5.9 2.8 0.8 0.6 2.8 4.1 0.0 0.7 0.0 0.7 1.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 10.5 1.6 15.8 11.1 9.3 2.3 10.1 4.3 4.1 GRM8 "GLUR8, GPRC1H, mGlu8, MGLUR8" ENSG00000179603 "Glutamate metabotropic receptor 8" O00222 7 126438598-127253294 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.5;liver: 8.0" "Cell line enhanced" "Detected in some" "HAP1: 5.4;HEK 293: 2.8;NTERA-2: 7.1;RH-30: 4.2;SCLC-21H: 6.4;SH-SY5Y: 3.4" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051481 Uncertain "HPA051481: " "unprognostic (4.57e-3)" "unprognostic (5.10e-4)" "unprognostic (1.21e-1)" "unprognostic (2.09e-2)" "unprognostic (1.83e-1)" "unprognostic (5.54e-2)" "unprognostic (2.06e-4)" "unprognostic (1.79e-1)" "unprognostic (8.90e-2)" "unprognostic (1.31e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-1)" "unprognostic (3.12e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (1.32e-2)" "unprognostic (1.12e-2)" 0.2 1.5 2.0 2.0 4.6 0.1 0.2 1.1 6.4 0.3 4.5 4.0 0.0 0.3 0.3 0.3 0.2 0.5 3.5 5.5 2.6 4.0 1.9 8.0 0.7 0.2 2.9 2.6 2.3 1.4 0.2 0.7 0.2 14.5 0.4 5.0 3.5 0.2 0.2 0.1 0.3 0.2 0.5 1.2 0.2 0.8 3.8 1.5 0.0 2.4 0.0 0.3 1.4 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.2 0.0 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.1 0.1 0.0 4.2 0.1 0.2 0.0 6.4 3.4 0.1 0.0 0.0 0.0 0.0 0.0 0.7 2.3 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.6 1.1 5.4 2.6 4.0 2.9 2.6 14.5 1.5 GRPR "BB2, BB2R" ENSG00000126010 "Gastrin releasing peptide receptor" P30550 X 16123556-16153021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 24.5" "Group enriched" "Detected in some" 10 "PC-3: 17.6;T-47d: 22.0;U-138 MG: 30.1" "Cancer enhanced" "Detected in some" "breast cancer: 6.6" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA069604 Supported "Plasma membrane" "Plasma membrane" "HPA069604: " "unprognostic (3.32e-2)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (2.87e-1)" "unprognostic (9.17e-2)" "unprognostic (5.06e-2)" "unprognostic (2.82e-1)" "unprognostic (1.01e-1)" "unprognostic (3.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (5.59e-2)" "unprognostic (2.15e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-1)" "unprognostic (2.86e-2)" 0.5 0.4 3.4 4.7 2.3 0.2 3.5 0.3 3.5 3.7 1.4 0.0 2.5 0.2 1.0 2.8 7.5 0.3 0.2 0.5 3.5 0.4 0.3 0.3 0.4 0.2 0.3 1.9 0.3 24.5 0.4 0.3 0.2 1.1 0.7 0.6 2.0 0.4 0.4 0.4 0.3 0.5 1.2 0.4 0.3 2.1 0.4 0.0 0.0 0.4 0.0 0.2 0.4 0.4 0.6 0.2 0.4 1.9 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.5 0.0 2.3 0.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.2 17.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 22.0 0.0 0.1 30.1 0.3 0.0 0.9 0.1 0.1 0.1 0.0 0.0 0.4 0.0 1.1 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.4 0.0 1.6 0.1 0.0 0.4 3.4 2.3 0.3 3.5 3.5 0.4 0.3 1.9 1.1 0.0 HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703343 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 50.9" "Cell line enriched" "Detected in some" 6 "HaCaT: 50.7" "Group enriched" "Detected in many" 8 "cervical cancer: 12.6;head and neck cancer: 16.1;lung cancer: 6.4;urothelial cancer: 9.2" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in some" 6 "neutrophil: 50.9" "Lineage enriched" "Detected in many" 8 "granulocytes: 50.9" HPA028660 Approved Supported "Cell Junctions" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.33e-1)" "unprognostic (3.33e-3)" "unprognostic (7.26e-2)" "unprognostic (2.17e-1)" "unprognostic (1.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.33e-2)" "unprognostic (4.83e-4)" "unprognostic (5.76e-2)" "unprognostic (5.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" 16.1 0.2 0.4 6.4 0.5 13.2 8.3 0.2 0.7 5.8 3.6 0.3 6.2 0.4 0.8 1.6 26.0 0.4 1.1 1.2 0.8 0.2 1.9 1.8 11.3 0.7 3.3 0.2 1.2 0.2 4.4 0.9 8.2 1.0 8.6 0.0 0.3 9.7 10.7 0.7 17.8 0.7 0.4 0.9 16.5 0.8 2.8 1.1 1.1 0.4 13.5 21.5 3.5 8.3 0.0 0.5 50.9 6.6 0.0 0.0 0.3 1.8 0.1 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 50.7 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 9.0 0.6 0.6 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 50.9 0.0 6.6 0.0 0.0 0.3 0.4 0.5 0.2 0.7 0.8 0.2 3.3 0.2 1.0 1.1 HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716892 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 47.7" "Group enriched" "Detected in some" 5 "HaCaT: 7.1;RT4: 27.3" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "midbrain: 3.5" "Group enriched" "Detected in some" 6 "basophil: 12.1;neutrophil: 47.7;non-classical monocyte: 21.3" "Group enriched" "Detected in many" 49 "granulocytes: 47.7;monocytes: 21.3" HPA028660 Approved Approved "Cell Junctions" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" 4.8 0.2 0.6 7.9 0.3 20.8 4.0 0.4 0.5 2.3 0.9 0.2 2.2 0.1 0.4 0.4 18.2 0.5 0.5 1.0 0.3 0.3 0.9 2.5 10.2 3.5 3.5 0.0 1.6 0.2 6.6 1.1 3.0 0.7 4.2 0.0 0.3 2.9 4.3 0.6 13.9 0.3 0.4 1.2 21.6 0.5 1.6 0.4 0.3 0.5 12.0 14.9 5.7 7.2 0.0 0.7 47.7 21.3 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 7.1 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 27.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 12.1 0.5 0.2 0.0 4.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 47.7 0.0 21.3 0.0 0.0 0.6 0.6 0.3 0.4 0.5 0.3 0.3 3.5 0.0 0.7 0.4 HCRTR1 OX1R ENSG00000121764 "Hypocretin receptor 1" O43613 1 31617686-31632518 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.0" "Cell line enhanced" "Detected in some" "HeLa: 1.7;HUVEC TERT2: 2.9;TIME: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014018 Approved "HPA014018: AB_1854810" "unprognostic (2.96e-2)" "unprognostic (2.34e-2)" "unprognostic (7.86e-3)" "unprognostic (3.72e-3)" "unprognostic (2.42e-1)" "unprognostic (3.45e-3)" "unprognostic (2.54e-5)" "unprognostic (3.58e-2)" "unprognostic (4.17e-2)" "unprognostic (1.19e-1)" "unprognostic (2.28e-1)" "unprognostic (2.93e-1)" "unprognostic (3.77e-3)" "unprognostic (2.16e-2)" "unprognostic (1.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" 3.3 4.3 0.9 0.3 1.4 1.6 2.7 0.7 4.5 0.1 0.3 0.0 0.0 0.2 0.6 0.3 0.7 0.5 0.8 1.8 0.8 4.6 0.5 0.1 0.2 0.6 1.1 0.0 0.5 0.3 0.0 1.7 2.3 8.0 0.5 0.2 0.7 0.5 0.0 2.4 1.1 0.5 0.0 0.5 0.6 0.4 0.4 0.0 0.0 2.9 0.8 0.2 0.6 0.1 1.1 0.2 0.0 0.2 0.2 0.5 0.1 0.4 0.0 0.3 0.1 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.6 0.6 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.7 0.0 0.0 1.0 0.4 0.0 0.0 0.5 0.0 2.9 0.4 0.2 0.0 0.5 0.1 0.1 0.1 0.0 1.1 0.1 0.0 0.0 0.7 0.1 0.4 0.3 0.2 0.0 0.2 0.0 1.6 0.1 0.2 0.3 0.4 0.5 0.1 0.2 0.0 0.6 1.0 0.0 0.2 0.0 0.5 0.2 0.0 0.1 0.2 0.0 0.1 1.1 0.1 0.1 0.0 0.2 0.1 0.2 0.0 0.1 0.9 1.4 0.7 4.5 0.8 4.6 1.1 0.0 8.0 0.0 HCRTR2 OX2R ENSG00000137252 "Hypocretin receptor 2" O43614 6 55106460-55282620 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 17.4" "Cell line enriched" "Detected in single" 6 "AF22: 4.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "pons and medulla: 17.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054516 Enhanced "HPA054516: " "unprognostic (4.86e-1)" "unprognostic (2.69e-2)" "unprognostic (1.86e-2)" "unprognostic (2.32e-1)" "unprognostic (7.45e-2)" "unprognostic (7.39e-2)" 0.1 0.2 1.7 0.0 1.3 0.0 0.1 0.6 2.2 0.1 0.1 0.3 0.0 0.0 0.1 0.5 0.0 0.1 0.1 1.1 0.9 4.2 3.7 0.1 0.4 0.1 2.6 1.7 1.7 0.0 0.0 0.3 2.2 17.4 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 1.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.7 1.3 0.6 2.2 0.9 4.2 2.6 1.7 17.4 0.0 HRH1 ENSG00000196639 "Histamine receptor H1" P35367 3 11137093-11263557 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 17.4;hTEC/SVTERT24-B: 17.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "T-reg: 3.5" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;T-cells: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029740 Uncertain Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA029740: AB_10601578" "unprognostic (4.60e-3)" "unprognostic (3.41e-2)" "unprognostic (6.37e-3)" "unprognostic (9.55e-2)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (9.60e-3)" "unprognostic (4.00e-3)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "prognostic unfavourable (1.27e-5)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-1)" 9.1 4.4 7.3 4.6 4.4 0.2 9.6 0.5 10.6 8.0 13.5 1.3 2.4 3.8 6.2 7.2 5.7 10.6 9.9 7.0 5.1 4.0 3.3 1.1 8.2 1.8 2.2 2.1 8.7 2.1 1.7 1.2 5.5 3.2 7.2 7.2 2.0 3.4 6.1 3.0 8.0 10.5 9.2 8.6 1.4 3.3 2.4 2.0 0.1 2.5 7.2 3.1 11.2 16.2 0.1 0.3 1.2 0.2 0.1 3.5 0.1 1.5 3.4 0.0 0.0 1.6 17.4 2.4 2.6 8.7 7.8 5.3 0.6 12.5 0.0 7.8 6.0 9.8 0.0 3.5 10.6 5.5 0.0 0.8 5.6 0.0 5.2 2.4 1.4 6.0 2.2 17.5 6.2 10.8 0.0 0.0 3.4 0.0 0.0 1.1 0.0 3.2 0.2 0.9 0.3 13.9 2.0 0.1 0.0 3.7 2.7 0.0 0.0 1.9 16.1 8.8 5.5 8.9 13.0 0.0 0.9 0.0 13.4 2.2 7.5 0.4 0.2 0.0 0.1 0.2 0.0 0.0 1.3 0.5 0.3 0.1 0.1 0.1 1.2 0.1 0.0 0.1 3.5 0.1 7.3 4.4 0.5 8.4 5.1 4.0 2.2 2.1 3.2 2.0 HRH2 ENSG00000113749 "Histamine receptor H2" P25021 5 175658030-175710756 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood: 45.7;bone marrow: 30.1" "Group enriched" "Detected in some" 4 "RPMI-8226: 35.4;SK-MEL-30: 10.6;THP-1: 9.8;U-937: 11.8" "Cancer enhanced" "Detected in many" "renal cancer: 4.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 45.7" "Group enriched" "Detected in many" 5 "granulocytes: 45.7;monocytes: 13.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA013770 Approved "HPA013770: AB_1851086" "unprognostic (8.56e-3)" "unprognostic (1.62e-1)" "unprognostic (6.66e-2)" "unprognostic (5.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (9.93e-2)" "unprognostic (5.76e-2)" "unprognostic (1.52e-1)" "unprognostic (2.35e-1)" "unprognostic (3.71e-3)" "unprognostic (2.01e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-3)" "unprognostic (1.77e-2)" 7.9 1.5 5.9 11.1 11.6 30.1 2.8 1.0 12.1 3.9 2.8 0.9 0.5 5.9 2.3 1.3 1.6 2.7 2.6 18.6 3.4 1.7 2.4 1.2 5.4 12.3 2.3 4.9 1.6 1.6 0.3 1.3 9.5 2.4 3.0 1.3 0.6 1.7 4.8 1.2 2.1 7.2 3.5 4.4 9.9 10.3 1.2 5.6 9.9 1.8 0.2 3.0 2.8 2.0 0.0 6.4 45.7 13.1 0.6 2.3 3.7 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 2.7 1.6 0.0 3.8 0.0 35.4 0.0 0.2 0.2 0.0 0.0 0.0 10.6 0.0 9.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.8 2.4 28.9 12.9 13.6 0.0 12.0 0.1 0.0 1.1 0.2 6.4 0.0 2.3 1.4 45.7 0.6 13.1 5.0 0.8 3.7 5.9 11.6 1.0 12.1 3.4 1.7 2.3 4.9 2.4 5.6 HRH4 "AXOR35, GPCR105, GPRv53, H4R, HH4R" ENSG00000134489 "Histamine receptor H4" Q9H3N8 18 24460629-24479957 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "blood: 48.5" "Cell line enhanced" "Detected in some" "HEL: 2.9;HL-60: 4.9;HMC-1: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 96 "basophil: 48.5;eosinophil: 16.7" "Lineage enriched" "Detected in single" 142 "granulocytes: 48.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035009 Uncertain "HPA035009: AB_10671507" "unprognostic (1.88e-1)" "unprognostic (2.62e-1)" "unprognostic (4.68e-2)" "unprognostic (9.83e-6)" "unprognostic (1.31e-2)" "unprognostic (3.61e-2)" "unprognostic (1.22e-1)" "unprognostic (8.96e-2)" "unprognostic (2.20e-1)" "unprognostic (3.30e-1)" "unprognostic (7.25e-2)" "unprognostic (2.91e-1)" "unprognostic (6.65e-7)" "unprognostic (1.89e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-4)" "unprognostic (7.70e-2)" 1.7 0.6 0.4 1.5 0.4 2.8 0.6 0.3 0.3 0.4 0.6 0.3 0.3 2.1 1.4 1.9 1.3 0.3 0.8 0.5 0.4 0.4 0.4 1.7 1.9 0.7 0.4 0.3 0.8 0.4 0.0 2.5 0.3 0.8 1.0 0.4 1.0 1.1 0.3 0.8 2.3 1.9 2.8 2.6 1.4 0.9 1.4 0.3 0.3 0.5 0.3 5.1 1.9 0.6 0.0 0.0 48.5 0.0 0.0 0.3 0.1 0.4 0.3 0.2 0.9 0.1 0.0 0.5 0.2 0.0 0.0 0.1 0.8 0.6 0.1 0.5 0.2 0.8 0.2 0.3 0.2 0.2 0.2 2.9 0.9 0.6 0.2 4.9 2.9 0.2 1.0 0.1 0.0 0.3 0.2 0.5 0.1 0.4 0.4 0.8 0.3 0.3 0.3 0.3 0.3 0.5 0.6 0.4 0.2 0.2 0.1 0.2 0.3 1.1 0.3 1.2 0.2 0.8 0.1 0.5 0.2 0.2 0.9 0.8 0.5 48.5 0.0 16.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.3 HTR1A "5-HT1A, ADRB2RL1, ADRBRL1" ENSG00000178394 "5-hydroxytryptamine receptor 1A" P08908 5 63960356-63962507 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 21.5;ovary: 10.4" "Group enriched" "Detected in some" 32 "NTERA-2: 5.3;SCLC-21H: 4.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "amygdala: 14.7;cerebral cortex: 10.7;hippocampal formation: 21.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA018073 Uncertain "HPA018073: AB_1856704" "unprognostic (1.81e-1)" 0.2 0.4 14.7 0.2 1.0 0.2 0.2 0.1 10.7 0.2 0.2 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.5 21.5 2.4 0.2 0.2 0.3 0.2 0.7 2.7 10.4 0.2 0.2 0.1 0.2 0.9 0.3 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.5 0.2 0.2 0.6 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 1.0 0.1 10.7 21.5 2.4 0.7 2.7 0.9 0.0 HTR1B "5-HT1B, 5-HT1DB, HTR1D2, S12" ENSG00000135312 "5-hydroxytryptamine receptor 1B" P28222 6 77461753-77463773 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;placenta: 14.2;stomach 1: 10.2" "Group enriched" "Detected in some" 15 "HUVEC TERT2: 40.8;TIME: 18.0" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 11.8" "Cell type enriched" "Detected in single" 17 "basophil: 1.6" "Lineage enriched" "Detected in single" 17 "granulocytes: 1.6" "Region enriched" "Detected in many" 4 "basal ganglia: 34.5" HPA028808 Enhanced Supported "Plasma membrane" "Plasma membrane" "HPA028808: " "unprognostic (3.86e-2)" "unprognostic (3.56e-1)" "unprognostic (7.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.11e-1)" "unprognostic (8.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-3)" "unprognostic (3.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" 2.2 1.5 1.3 1.1 11.8 0.3 2.4 0.4 3.7 2.9 0.6 0.1 0.0 0.6 1.1 1.0 1.4 0.8 2.8 0.4 1.0 2.1 0.9 0.3 1.1 0.3 1.2 0.9 1.1 0.5 0.3 0.5 14.2 3.0 1.6 0.4 0.3 1.3 1.2 0.9 0.5 0.4 4.1 0.6 0.4 10.2 1.5 0.6 0.0 0.5 0.0 0.3 2.6 1.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.4 1.0 40.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 11.8 0.4 3.7 1.0 2.1 1.2 0.9 3.0 0.6 HTR1E 5-HT1E ENSG00000168830 "5-hydroxytryptamine receptor 1E" P28566 6 86937306-87016683 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.4;ovary: 13.3" "Group enriched" "Detected in some" 22 "PC-3: 2.9;SH-SY5Y: 11.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA004931 Approved "HPA004931: AB_1856706" "unprognostic (2.25e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.25e-1)" 0.5 0.6 8.9 0.6 13.3 0.5 0.5 5.4 16.4 1.6 0.5 0.0 0.0 0.5 5.1 1.1 0.6 0.5 0.8 0.5 4.1 2.8 0.5 0.5 0.5 0.5 1.8 11.4 13.3 0.8 0.5 0.3 0.5 2.2 1.1 0.5 0.0 0.5 1.2 0.5 0.5 0.5 2.9 0.6 0.5 3.6 1.4 1.5 0.0 2.7 0.0 0.5 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 13.3 5.4 16.4 4.1 2.8 1.8 11.4 2.2 1.5 HTR1F "5-HT1F, HTR1EL" ENSG00000179097 "5-hydroxytryptamine receptor 1F" P30939 3 87990696-87993835 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "placenta: 5.7" "Group enriched" "Detected in some" 6 "A549: 1.2;K-562: 4.4;LHCN-M2: 4.3" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 16 "basophil: 3.2" "Lineage enriched" "Detected in single" 16 "granulocytes: 3.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005555 Uncertain "HPA005555: AB_1856708" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" "unprognostic (2.58e-1)" "unprognostic (9.03e-2)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (4.78e-1)" "unprognostic (1.58e-1)" "unprognostic (2.77e-2)" "unprognostic (2.24e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (2.67e-6)" "unprognostic (1.25e-4)" "unprognostic (1.55e-2)" "unprognostic (3.33e-2)" "unprognostic (3.31e-2)" 2.8 0.5 0.7 0.0 0.6 1.5 1.6 0.0 1.8 1.4 0.0 0.0 1.2 0.3 0.1 0.4 0.1 0.3 0.6 0.4 0.6 0.0 0.9 0.1 0.8 0.4 0.7 0.3 1.4 5.7 0.4 0.0 0.1 1.0 0.6 0.4 0.0 1.3 0.3 1.7 0.0 0.3 1.5 0.5 0.6 0.7 0.1 0.2 3.2 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 HTR2A "5-HT2A, HTR2" ENSG00000102468 "5-hydroxytryptamine receptor 2A" P28223 13 46831550-46897076 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "Behavior, Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 30.4" "Cell line enhanced" "Detected in some" "ASC diff: 3.7;ASC TERT1: 9.1;BEWO: 2.8;HEL: 2.8;U-138 MG: 4.6;U-2 OS: 2.9;U-87 MG: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "neutrophil: 1.2;plasmacytoid DC: 1.2" "Group enriched" "Detected in many" 8 "dendritic cells: 1.2;granulocytes: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014011 Enhanced "HPA014011: AB_1856709" "unprognostic (8.01e-2)" "unprognostic (2.71e-2)" "unprognostic (9.49e-2)" "unprognostic (7.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.99e-1)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (5.27e-2)" "unprognostic (3.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.90e-1)" "unprognostic (9.94e-5)" "unprognostic (4.78e-3)" "unprognostic (2.54e-1)" "unprognostic (2.91e-2)" "unprognostic (8.28e-2)" 1.9 1.0 9.5 1.7 13.5 0.6 1.3 0.6 30.4 1.6 1.2 1.2 0.0 1.1 1.6 0.6 1.4 1.1 2.9 1.5 3.8 5.1 0.7 0.6 1.0 0.6 3.3 13.3 1.0 0.6 0.6 0.5 0.6 1.8 0.9 1.6 2.0 0.6 1.5 0.9 0.7 1.1 4.4 1.2 0.6 1.0 1.5 0.7 0.0 0.7 0.0 0.8 1.9 1.5 0.1 1.2 1.2 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 3.7 9.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 1.0 0.1 4.6 2.9 0.0 0.2 0.1 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 1.2 0.0 1.5 9.5 13.5 0.6 26.4 3.8 5.1 3.3 13.3 1.8 0.7 HTR2B "5-HT(2B), 5-HT2B" ENSG00000135914 "5-hydroxytryptamine receptor 2B" P41595 2 231108230-231125118 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 26.0" "Group enriched" "Detected in some" 4 "HHSteC: 6.8;HSkMC: 13.0;SK-MEL-30: 23.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "basophil: 3.8;T-reg: 2.9" "Group enriched" "Detected in many" 29 "granulocytes: 3.8;T-cells: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012867, HPA063658" Enhanced Supported Nucleoplasm Nucleoplasm "HPA012867: AB_1856710, HPA063658: " "unprognostic (1.86e-1)" "unprognostic (3.55e-2)" "unprognostic (1.20e-3)" "unprognostic (1.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.53e-2)" "unprognostic (1.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.15e-4)" "unprognostic (3.59e-1)" "unprognostic (2.17e-2)" "unprognostic (1.42e-3)" "unprognostic (7.44e-4)" "unprognostic (1.81e-1)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" 2.3 17.9 0.2 5.8 0.3 0.7 4.1 0.3 0.6 17.8 7.3 0.2 1.7 1.0 14.9 9.5 5.7 1.9 0.8 4.6 0.3 0.3 5.6 2.5 1.8 0.5 0.3 0.4 4.3 0.3 0.3 0.4 26.0 0.9 2.6 1.5 1.8 0.5 1.0 0.2 0.2 6.3 12.8 0.3 0.4 5.2 3.3 0.3 2.4 6.8 1.0 0.4 4.9 0.8 0.0 0.1 3.8 0.0 0.0 2.9 0.0 0.1 0.2 0.0 0.1 0.4 3.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.8 0.1 0.2 13.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 23.8 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.8 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 2.9 0.0 0.2 0.3 0.3 0.6 0.3 0.3 0.3 0.4 0.9 0.3 HTR4 5-HT4 ENSG00000164270 "5-hydroxytryptamine receptor 4" Q13639 5 148451032-148677235 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 18.1;heart muscle: 7.2;intestine: 14.6;pituitary gland: 5.9" "Cell line enriched" "Detected in single" 5 "Karpas-707: 2.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 18.1" "Cell type enriched" "Detected in single" 8 "T-reg: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040591 Enhanced "HPA040591: " "unprognostic (1.12e-1)" "unprognostic (4.60e-2)" "unprognostic (7.74e-2)" "unprognostic (2.37e-1)" "unprognostic (5.02e-2)" "unprognostic (3.77e-2)" "unprognostic (4.68e-2)" "unprognostic (1.10e-2)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (3.40e-2)" "unprognostic (2.25e-1)" "unprognostic (4.49e-2)" "unprognostic (8.83e-5)" 0.4 1.4 1.9 1.1 18.1 0.1 0.2 0.1 3.2 0.6 4.3 0.0 0.0 8.0 0.3 0.1 0.3 0.4 1.5 7.2 5.2 0.6 0.1 0.2 0.3 0.2 0.5 1.3 0.2 0.1 0.1 5.9 0.1 0.1 0.1 4.9 0.0 0.2 0.2 0.2 0.2 14.6 1.1 0.3 0.2 0.2 0.2 2.4 0.0 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 1.9 18.1 0.1 3.2 5.2 0.6 0.5 1.3 0.1 2.4 HTR5A 5-HT5A ENSG00000157219 "5-hydroxytryptamine receptor 5A" P47898 7 155070324-155085749 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 15.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB017467 Approved "CAB017467: AB_2122566" "unprognostic (1.62e-2)" "unprognostic (1.15e-1)" 0.4 0.4 2.6 0.4 3.9 0.4 0.4 15.4 15.0 0.4 0.4 0.0 0.0 0.4 0.4 0.4 0.4 0.4 0.4 0.4 2.6 5.9 0.4 0.4 0.4 0.4 2.3 2.5 0.4 0.4 0.4 0.1 0.4 2.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 0.4 0.4 0.8 0.4 0.4 1.4 0.3 3.3 0.4 0.0 0.4 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 3.9 15.4 9.8 2.6 5.9 2.3 2.5 2.4 0.3 HTR6 "5-HT6, 5-HT6R" ENSG00000158748 "5-hydroxytryptamine receptor 6" P50406 1 19665287-19679562 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 24.6" "Cell line enhanced" "Detected in some" "MCF7: 1.2;NTERA-2: 2.4;SH-SY5Y: 6.5" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Group enriched" "Detected in many" 5 "basal ganglia: 24.6;cerebral cortex: 6.6" "Cell type enhanced" "Detected in some" "MAIT T-cell: 1.4;naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 9.5" HPA068165 Uncertain "HPA068165: " "unprognostic (2.34e-2)" "unprognostic (1.84e-1)" "unprognostic (7.19e-3)" "unprognostic (3.84e-5)" "unprognostic (1.38e-4)" "unprognostic (2.69e-2)" "unprognostic (1.36e-1)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (5.33e-3)" "unprognostic (8.63e-2)" "unprognostic (5.47e-4)" "unprognostic (1.28e-1)" "unprognostic (2.49e-1)" "unprognostic (6.13e-3)" "unprognostic (2.02e-1)" 0.4 0.5 1.2 1.4 24.6 0.4 0.4 0.2 6.6 0.6 0.4 0.0 0.0 0.6 0.6 0.5 0.5 0.6 0.5 0.4 1.4 1.0 0.3 0.3 0.3 1.4 0.5 2.2 0.3 0.3 0.3 0.4 0.3 0.4 0.4 0.3 0.0 0.5 0.3 0.3 0.8 0.5 0.5 0.2 0.4 0.5 0.8 3.2 0.0 0.3 0.0 2.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 1.4 0.0 1.0 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.2 24.6 0.2 6.6 1.4 1.0 0.5 2.2 0.4 3.2 HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90857698 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 30.8;testis: 14.3" "Cell line enhanced" "Detected in some" "HBEC3-KT: 8.1;hTCEpi: 7.3;hTERT-HME1: 24.5;LHCN-M2: 9.8;U-87 MG: 7.5;WM-115: 9.3" "Group enriched" "Detected in some" 5 "cervical cancer: 0.9;head and neck cancer: 3.3;lung cancer: 0.9;urothelial cancer: 1.3" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 12 "myeloid DC: 4.6" "Lineage enriched" "Detected in single" 12 "dendritic cells: 4.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB022708, HPA073617" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB022708: , HPA073617: " "unprognostic (1.17e-1)" "unprognostic (1.24e-2)" "unprognostic (4.72e-2)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (1.71e-2)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (1.15e-1)" "unprognostic (4.58e-3)" "unprognostic (3.32e-1)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" 1.0 0.5 2.4 1.1 2.5 0.5 0.7 0.3 4.3 0.6 0.8 1.7 1.2 0.8 0.4 0.3 1.0 0.4 1.3 0.6 9.9 5.1 0.3 0.6 0.5 0.7 1.7 1.8 0.4 1.4 30.8 0.2 0.5 3.1 1.0 1.2 0.4 0.6 0.3 1.7 0.9 2.2 3.6 1.5 1.3 1.5 14.3 1.0 0.0 0.3 0.1 0.6 3.5 2.1 0.0 4.6 0.0 0.3 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.5 0.2 0.5 0.7 0.0 0.9 0.0 0.0 0.1 3.3 0.9 8.1 2.0 0.0 0.1 0.0 0.0 0.0 3.8 0.0 0.4 5.8 7.3 2.4 24.5 0.0 0.0 0.0 9.8 0.0 0.0 0.1 0.9 1.2 0.7 0.1 0.0 0.0 0.9 0.3 0.0 0.3 0.0 3.8 0.0 0.2 0.2 4.5 0.0 0.0 6.8 0.0 0.0 0.0 7.5 0.0 9.3 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.1 4.6 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.1 0.1 2.4 2.5 0.3 4.3 9.9 5.1 1.7 1.8 3.1 1.0 KISS1R "AXOR12, GPR54, HOT7T175" ENSG00000116014 "KISS1 receptor" Q969F8 19 917287-921015 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8;lymphoid tissue: 12.4" "Cell line enhanced" "Detected in some" "K-562: 10.5;RPMI-8226: 25.7;SCLC-21H: 5.4;SH-SY5Y: 14.4" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.0;neutrophil: 1.8" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007156, HPA071913" Approved Supported "Vesicles,Plasma membrane" "Plasma membrane" Vesicles "HPA007156: , HPA071913: " "unprognostic (1.54e-1)" "unprognostic (3.01e-2)" "unprognostic (9.42e-2)" "unprognostic (2.15e-1)" "unprognostic (8.46e-3)" "unprognostic (9.23e-2)" "unprognostic (1.65e-2)" "unprognostic (3.23e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (7.17e-2)" "prognostic unfavourable (3.33e-6)" "unprognostic (1.87e-1)" "unprognostic (8.09e-3)" "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" 0.2 0.2 2.1 2.1 4.1 0.2 0.3 0.1 4.7 0.1 0.3 0.1 0.1 0.4 0.2 0.1 0.1 0.2 0.1 0.1 1.0 6.8 1.4 0.1 0.3 12.4 1.1 0.1 0.4 3.6 0.1 2.0 1.0 0.8 0.2 0.2 0.3 0.3 0.1 0.1 0.1 0.7 0.5 1.0 2.4 0.4 0.1 0.1 0.1 0.1 0.1 0.6 0.5 0.1 0.6 0.0 1.8 0.0 0.0 2.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.2 2.8 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.2 0.1 0.0 0.4 0.3 0.7 0.0 25.7 0.0 0.0 5.4 14.4 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.7 0.0 0.0 0.1 2.0 0.6 1.8 0.0 0.0 0.0 0.1 0.0 2.1 4.1 0.1 1.5 1.0 6.8 1.1 0.1 0.8 0.1 LGR4 GPR48 ENSG00000205213 "Leucine rich repeat containing G protein-coupled receptor 4" Q9BXB1 11 27365961-27472775 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, Immunity, Innate immunity, Spermatogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 29.7;RPTEC TERT1: 36.4;U-2197: 29.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 1.4;intermediate monocyte: 1.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030267, HPA054350" Uncertain Approved "Centriolar satellite" "Centriolar satellite" "HPA030267: AB_10610004, HPA054350: " "unprognostic (5.27e-3)" "unprognostic (5.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.59e-1)" "unprognostic (4.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "unprognostic (2.00e-2)" "unprognostic (4.63e-2)" "unprognostic (5.84e-3)" "unprognostic (2.10e-1)" "prognostic favourable (2.00e-7)" "unprognostic (5.01e-1)" "unprognostic (3.59e-1)" "unprognostic (3.54e-2)" "unprognostic (1.76e-1)" 7.6 10.4 9.4 4.0 11.2 0.9 8.2 15.6 7.6 6.0 18.7 7.8 8.5 11.4 6.5 7.3 9.5 5.7 9.5 14.7 7.1 3.7 30.6 30.5 2.3 0.5 9.1 6.9 12.5 37.0 5.0 5.6 24.9 12.1 8.3 19.3 15.7 8.7 13.3 7.5 11.7 17.5 6.8 8.2 6.5 15.8 7.5 6.8 2.1 7.9 7.2 3.3 7.0 8.4 0.5 0.2 1.4 1.3 0.1 0.5 0.0 9.7 17.9 17.9 2.0 1.6 1.1 20.3 5.6 5.2 5.0 4.3 2.6 0.2 0.0 3.7 7.4 16.4 29.7 11.0 8.6 0.0 13.3 5.3 10.4 12.5 0.5 0.5 0.0 1.5 7.0 3.4 7.6 2.5 1.5 0.0 2.0 3.1 0.0 0.9 17.2 7.3 0.0 12.2 1.1 36.4 4.2 0.2 2.1 2.7 16.4 1.6 5.4 8.2 8.0 3.7 3.1 29.8 5.1 6.8 5.1 0.0 6.3 0.0 2.3 1.4 0.3 0.0 0.2 1.3 0.2 0.3 0.0 0.5 0.2 0.5 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 9.4 11.2 15.6 7.6 7.1 3.7 9.1 6.9 12.1 6.8 LGR5 "FEX, GPR49, GPR67, HG38" ENSG00000139292 "Leucine rich repeat containing G protein-coupled receptor 5" O75473 12 71439770-71586310 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3;fallopian tube: 19.9;placenta: 21.6;skeletal muscle: 26.6" "Group enriched" "Detected in some" 5 "Hep G2: 15.8;SH-SY5Y: 46.7" "Group enriched" "Detected in many" 7 "colorectal cancer: 16.8;endometrial cancer: 26.8;ovarian cancer: 9.8;stomach cancer: 6.1" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "memory B-cell: 1.1" "Lineage enriched" "Detected in single" 10 "B-cells: 1.1" "Region enriched" "Detected in some" 8 "olfactory region: 41.8" "Low region specificity" "Detected in many" HPA012530 Approved "HPA012530: AB_1849329" "unprognostic (5.19e-2)" "unprognostic (3.79e-1)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-3)" "unprognostic (1.52e-1)" "prognostic favourable (5.09e-4)" "unprognostic (1.46e-1)" "unprognostic (2.60e-1)" "unprognostic (3.71e-1)" "unprognostic (8.10e-2)" "unprognostic (2.01e-5)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (2.28e-2)" "unprognostic (6.25e-3)" 2.3 2.2 3.5 0.8 18.1 0.4 2.1 0.9 9.5 2.2 4.2 24.5 0.0 6.1 4.9 1.7 0.6 19.9 0.8 0.8 5.0 3.4 0.9 1.4 1.4 0.4 32.3 5.1 1.5 0.6 1.0 2.0 21.6 10.8 1.8 4.6 0.9 3.1 9.0 26.6 4.0 6.5 0.7 15.0 0.6 2.9 0.7 25.7 0.0 0.9 0.9 2.1 0.7 1.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 5.2 0.0 0.4 15.8 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 1.0 0.0 0.0 0.0 6.3 0.1 46.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 18.1 0.9 9.5 5.0 3.4 32.3 5.1 10.8 25.7 LGR6 FLJ14471 ENSG00000133067 "Leucine rich repeat containing G protein-coupled receptor 6" Q9HBX8 1 202193901-202319781 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 49.6" "Cell line enhanced" "Detected in some" "A549: 16.3;CAPAN-2: 14.5;HaCaT: 7.8;HeLa: 3.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "gdT-cell: 14.3;memory CD8 T-cell: 8.3;naive CD8 T-cell: 4.7" "Lineage enriched" "Detected in single" 41 "T-cells: 14.3" "Region enriched" "Detected in some" 9 "olfactory region: 30.0" HPA008556 Approved Approved "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA008556: " "unprognostic (4.72e-3)" "unprognostic (5.29e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-2)" "prognostic unfavourable (4.35e-4)" "unprognostic (1.08e-1)" "unprognostic (5.13e-2)" "unprognostic (9.23e-2)" "unprognostic (1.12e-1)" "unprognostic (2.54e-2)" "unprognostic (4.01e-2)" "unprognostic (7.89e-2)" "unprognostic (1.00e-2)" "unprognostic (1.17e-3)" "unprognostic (2.08e-1)" "unprognostic (1.70e-1)" "unprognostic (7.83e-2)" 1.1 0.1 0.9 0.8 3.2 1.8 7.9 6.0 2.4 2.6 2.2 1.5 0.5 0.2 1.6 7.3 4.4 13.8 49.6 12.3 0.7 3.3 0.9 1.4 6.9 1.1 6.8 0.2 2.2 0.5 0.1 15.9 0.9 9.3 6.7 1.1 0.8 8.5 2.5 0.3 3.2 1.6 2.6 1.6 5.3 0.7 4.9 3.9 0.2 4.1 2.6 3.4 3.2 2.9 0.0 0.0 0.0 0.0 0.3 14.3 2.5 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 1.6 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.9 0.0 1.7 8.3 0.0 0.0 0.7 4.7 0.0 0.3 0.0 0.0 0.4 2.5 0.9 3.2 6.0 2.4 0.7 3.3 6.8 0.2 9.3 3.9 LHCGR "HHG, LCGR, LGR2, LHR, ULG5" ENSG00000138039 "Luteinizing hormone/choriogonadotropin receptor" P22888 2 48686775-48755730 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.3;testis: 18.8" "Group enriched" "Detected in some" 5 "AF22: 2.8;HSkMC: 1.0;NTERA-2: 1.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" CAB009814 Uncertain "CAB009814: AB_2135467" "unprognostic (8.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.97e-2)" "unprognostic (2.24e-2)" "unprognostic (5.22e-2)" 3.6 2.9 0.3 1.4 6.1 0.0 1.6 0.3 0.4 0.2 0.5 0.2 0.0 0.2 0.4 0.3 2.1 0.2 1.8 0.6 0.7 0.4 0.9 0.1 0.4 0.1 2.6 0.0 5.0 0.1 0.0 2.7 0.1 1.4 0.4 0.2 0.3 1.0 0.1 0.2 0.6 0.3 1.0 10.3 0.1 0.6 18.8 0.0 0.4 2.2 0.1 0.1 0.4 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 6.1 0.3 0.4 0.7 0.4 2.6 0.0 1.4 0.0 LPAR1 "edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.4" "Cell line enhanced" "Detected in many" "ASC diff: 96.2;ASC TERT1: 56.2;BJ hTERT+: 68.0;HSkMC: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 7.5;eosinophil: 15.6" "Group enriched" "Detected in many" 6 "granulocytes: 15.6;monocytes: 7.5" "Low region specificity" "Detected in all" HPA050667 Approved "Nuclear speckles,Plasma membrane" "Nuclear speckles" "Plasma membrane" "HPA050667: " "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 16.3 9.5 55.8 12.0 56.2 0.3 14.8 4.7 30.9 43.7 12.3 71.4 3.4 9.4 12.1 12.3 10.6 10.1 9.8 8.5 55.6 30.6 5.7 1.9 7.3 10.5 59.4 17.0 8.9 4.6 1.1 2.3 25.7 29.1 9.4 12.8 3.5 5.6 17.2 3.3 6.9 10.2 14.0 69.8 9.5 6.5 4.8 49.4 0.1 6.2 3.2 11.3 15.4 17.8 0.0 1.9 15.6 7.5 1.8 0.0 1.6 1.8 3.5 4.9 0.0 96.2 56.2 0.0 24.0 68.0 16.8 7.6 0.4 0.2 0.0 0.0 24.8 7.2 0.0 18.7 13.9 0.0 0.6 0.0 0.2 0.0 26.0 0.0 0.0 40.8 1.1 8.3 15.8 0.3 0.0 0.0 12.9 0.0 0.0 0.0 0.9 19.4 0.0 3.6 0.0 3.8 3.2 0.1 1.1 0.4 0.0 0.0 1.6 0.0 0.0 8.0 0.2 5.7 0.0 0.2 0.0 0.0 1.2 0.0 8.7 0.9 7.5 15.6 0.0 2.6 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.6 1.8 1.1 0.1 0.0 1.6 55.8 56.2 4.7 29.5 55.6 30.6 59.4 17.0 29.1 49.4 LPAR2 "EDG-4, EDG4, LPA2" ENSG00000064547 "Lysophosphatidic acid receptor 2" Q9HBW0 19 19623668-19628930 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 43.7" "Cell line enhanced" "Detected in many" "HMC-1: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA019616 Approved "HPA019616: AB_1847988" "unprognostic (1.60e-2)" "unprognostic (1.83e-3)" "unprognostic (6.39e-2)" "unprognostic (1.19e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-3)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (2.32e-1)" "unprognostic (1.05e-3)" "unprognostic (8.07e-2)" "unprognostic (6.03e-2)" "prognostic unfavourable (1.61e-7)" "prognostic favourable (1.43e-4)" "unprognostic (2.40e-1)" "unprognostic (5.87e-2)" "unprognostic (2.29e-2)" 3.4 1.2 2.2 12.6 1.9 26.1 4.6 1.3 2.4 6.5 7.9 1.4 13.8 5.1 2.4 3.9 10.5 4.4 17.9 1.9 2.2 4.0 7.0 2.4 11.0 17.7 2.4 1.1 6.1 27.3 7.4 4.0 4.2 2.7 8.2 4.3 7.4 12.3 12.3 1.6 7.2 16.4 1.1 2.8 31.4 19.2 43.7 1.1 18.5 23.2 10.0 21.1 4.9 4.1 3.8 1.1 6.7 1.0 1.7 15.9 4.1 12.7 1.4 15.2 3.4 3.9 1.9 13.1 0.8 1.2 0.6 1.1 9.1 12.3 8.3 8.5 1.2 13.5 2.3 4.6 0.6 3.5 3.9 1.9 2.6 0.6 0.5 3.0 31.8 2.1 11.5 0.6 0.9 0.3 1.8 3.2 0.5 20.8 1.8 5.1 15.1 5.9 8.1 1.2 3.7 9.4 18.8 5.4 10.1 3.4 2.8 1.9 7.1 19.4 3.8 2.9 2.5 5.3 1.2 1.5 4.2 2.8 0.6 22.2 1.4 0.1 0.6 2.2 6.1 0.7 11.2 3.8 14.0 8.0 0.4 2.0 12.8 9.2 6.7 1.7 1.0 1.1 15.9 4.1 2.2 1.9 1.3 2.4 2.2 4.0 2.4 1.1 2.7 1.1 LPAR3 "Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3" ENSG00000171517 "Lysophosphatidic acid receptor 3" Q9UBY5 1 84811602-84893213 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 32.0" "Cell line enhanced" "Detected in some" "HAP1: 13.0;HBEC3-KT: 16.0;hTCEpi: 17.2;NTERA-2: 14.5;PC-3: 16.2;SK-MEL-30: 15.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 24.7" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in some" "olfactory region: 3.5" "Low region specificity" "Detected in many" HPA013421 Supported "Plasma membrane" "Plasma membrane" "HPA013421: AB_1847990" "unprognostic (2.85e-2)" "unprognostic (1.67e-1)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (2.72e-2)" "unprognostic (6.46e-3)" "unprognostic (1.15e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "prognostic favourable (4.31e-5)" "unprognostic (1.11e-2)" "unprognostic (7.52e-2)" "unprognostic (1.13e-4)" "unprognostic (4.11e-2)" "unprognostic (1.19e-1)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" 0.0 1.2 2.4 0.5 1.9 0.3 0.7 0.2 3.5 8.8 0.4 2.2 2.9 0.1 2.4 11.8 7.2 32.0 0.5 12.4 3.7 0.9 0.0 0.1 4.2 0.1 0.1 2.6 5.1 8.6 0.3 0.4 1.1 6.8 11.5 0.5 0.7 5.0 4.7 0.3 4.0 0.5 0.5 0.3 0.1 0.2 14.7 0.2 0.7 0.2 3.3 4.3 4.8 6.9 0.6 0.4 1.1 0.1 1.8 0.5 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.4 0.2 1.2 1.1 0.8 0.0 0.0 0.0 0.2 0.0 0.2 13.0 16.0 1.0 0.1 2.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 17.2 4.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 16.2 0.0 0.0 0.0 0.0 3.7 0.9 0.7 0.0 0.3 15.3 0.0 1.2 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.1 0.2 0.3 0.0 0.2 0.4 0.5 0.5 0.3 0.6 0.4 0.3 1.1 1.8 0.1 0.4 0.1 0.1 2.4 1.9 0.2 3.5 3.7 0.9 0.1 2.6 6.8 0.2 LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78757094 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.8;ovary: 10.0" "Cell line enhanced" "Detected in some" "AF22: 10.1;NTERA-2: 16.4;RH-30: 6.9;U-937: 3.9" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 12 "basophil: 7.4" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: , HPA054951: , HPA055571: " "unprognostic (1.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.58e-1)" "unprognostic (5.81e-4)" "unprognostic (3.12e-2)" "unprognostic (4.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.57e-1)" "unprognostic (6.75e-2)" "unprognostic (6.73e-2)" "unprognostic (8.91e-2)" "unprognostic (4.86e-4)" "unprognostic (2.99e-5)" "unprognostic (9.27e-3)" "unprognostic (1.00e-1)" "unprognostic (3.58e-2)" "unprognostic (6.03e-3)" 1.5 0.2 6.0 1.0 2.1 0.6 2.0 4.9 3.7 1.8 0.9 7.4 0.7 0.2 2.9 0.8 1.8 1.1 2.1 1.9 15.8 1.4 0.3 0.3 0.3 0.2 2.4 4.0 10.0 0.7 0.1 0.7 0.2 3.6 0.6 1.2 0.5 1.0 1.6 0.2 1.6 0.9 1.3 3.8 0.4 1.5 0.8 5.6 0.0 0.6 0.8 1.2 1.4 0.9 0.0 0.5 7.4 0.0 0.0 0.0 0.1 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.6 1.1 1.4 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 2.3 0.0 0.4 1.8 16.4 0.2 0.8 6.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.2 0.0 0.6 1.4 0.0 0.7 0.7 3.9 1.6 7.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 6.0 2.1 4.9 3.5 15.8 1.4 2.4 4.0 3.6 5.6 LPAR5 "GPR92, GPR93, KPG_010, LPA5" ENSG00000184574 "Lysophosphatidic acid receptor 5" Q9H1C0 12 6618835-6636447 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood: 28.4;brain: 20.3;esophagus: 21.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.5;HEL: 13.7;HMC-1: 19.9;K-562: 10.2;U-698: 9.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 28.4;T-cells: 23.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA013170 Approved "HPA013170: AB_1849314" "unprognostic (1.94e-1)" "unprognostic (6.43e-2)" "unprognostic (1.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (1.37e-1)" "unprognostic (5.95e-2)" "unprognostic (3.45e-1)" "unprognostic (1.41e-2)" "unprognostic (3.62e-3)" "unprognostic (2.07e-1)" "unprognostic (6.27e-2)" "unprognostic (7.99e-3)" "unprognostic (5.43e-1)" "prognostic favourable (6.56e-5)" "unprognostic (7.43e-2)" 2.1 3.2 11.2 5.6 12.4 1.1 1.6 1.3 8.9 5.8 10.2 20.3 0.5 11.2 0.7 3.2 21.1 2.0 1.9 3.6 10.9 4.0 1.3 1.5 2.1 9.2 9.3 4.0 0.9 0.8 0.9 1.4 7.2 9.2 1.7 9.7 1.7 6.3 1.6 0.3 6.8 9.3 1.3 11.7 10.6 8.3 1.7 13.6 2.2 2.0 1.1 13.5 3.4 9.0 28.4 5.5 2.5 1.8 1.3 23.9 6.5 4.0 0.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 7.5 3.2 1.0 0.0 5.2 0.0 2.2 0.0 0.0 0.0 13.7 0.4 0.3 0.0 0.0 19.9 0.0 2.5 0.1 1.1 0.0 10.2 0.0 0.0 0.3 0.4 4.3 0.0 0.7 3.5 0.0 0.0 0.0 2.4 0.1 0.1 2.0 0.0 0.0 0.0 1.6 0.1 0.0 3.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 2.5 0.1 0.0 23.9 1.0 18.0 28.4 4.0 14.1 5.5 27.8 4.0 8.9 0.2 1.3 1.8 0.3 5.4 6.5 11.2 12.4 1.3 8.9 10.9 4.0 9.3 4.0 9.2 13.6 LPAR6 "P2RY5, P2Y5" ENSG00000139679 "Lysophosphatidic acid receptor 6" P43657 13 48389567-48444704 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 54.2" "Cell line enhanced" "Detected in many" "AF22: 13.2;HUVEC TERT2: 21.5;MOLT-4: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028934 Approved "HPA028934: " "unprognostic (1.19e-1)" "unprognostic (4.10e-1)" "unprognostic (8.82e-2)" "unprognostic (9.30e-3)" "unprognostic (2.31e-1)" "unprognostic (5.57e-2)" "unprognostic (7.40e-2)" "prognostic favourable (6.22e-4)" "unprognostic (1.07e-2)" "unprognostic (8.00e-2)" "unprognostic (2.63e-1)" "unprognostic (2.46e-1)" "prognostic unfavourable (3.60e-4)" "unprognostic (6.54e-2)" "unprognostic (3.81e-2)" "unprognostic (2.09e-2)" "unprognostic (1.94e-2)" 10.9 6.0 7.6 5.3 10.0 0.3 11.0 5.4 10.6 8.7 4.5 11.1 2.9 2.7 6.5 9.7 25.6 4.9 8.0 5.6 8.4 4.1 7.6 4.7 9.6 9.4 7.9 10.9 3.7 2.9 2.0 4.8 18.7 14.1 17.7 6.3 5.9 18.3 7.8 3.4 7.5 5.5 6.0 17.4 9.4 4.4 54.2 12.6 2.9 7.3 2.9 9.1 9.6 21.3 0.3 7.3 1.6 31.0 1.8 23.0 16.3 0.0 1.2 13.2 0.0 4.4 5.5 0.1 2.7 7.7 0.5 1.5 0.0 3.9 0.0 0.0 2.9 7.7 0.4 4.3 0.2 0.0 2.6 0.1 0.1 9.5 2.9 0.0 0.1 7.2 7.7 0.4 4.3 21.5 0.0 0.2 2.6 0.0 11.7 3.7 5.2 3.5 10.0 0.0 0.1 3.6 7.9 0.0 0.0 0.0 0.0 2.6 1.3 0.1 5.5 1.5 0.0 0.1 0.7 0.0 0.0 0.0 0.4 0.6 4.7 0.3 20.8 0.0 7.6 31.0 4.1 0.3 21.5 9.0 7.3 0.1 15.5 4.8 1.6 1.8 26.6 0.3 23.0 16.3 7.6 10.0 5.4 10.6 8.4 4.1 7.9 10.9 14.1 12.6 LTB4R "BLTR, CMKRL1, GPR16, LTB4R1, P2RY7, P2Y7" ENSG00000213903 "Leukotriene B4 receptor" Q15722 14 24311450-24318036 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 36.8;skin 1: 47.0" "Cell line enhanced" "Detected in many" "HaCaT: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "classical monocyte: 13.8;eosinophil: 13.9;neutrophil: 36.8" "Group enriched" "Detected in many" 6 "granulocytes: 36.8;monocytes: 13.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA003873 Approved "HPA003873: AB_1078288" "unprognostic (4.07e-2)" "unprognostic (7.67e-2)" "unprognostic (3.67e-3)" "unprognostic (2.40e-3)" "unprognostic (4.90e-2)" "unprognostic (9.00e-3)" "unprognostic (1.15e-2)" "unprognostic (8.63e-2)" "unprognostic (3.68e-1)" "unprognostic (2.06e-1)" "prognostic favourable (1.85e-4)" "unprognostic (7.25e-2)" "prognostic unfavourable (3.44e-15)" "unprognostic (2.88e-1)" "unprognostic (2.97e-1)" "unprognostic (6.59e-2)" "unprognostic (7.45e-2)" 7.8 2.7 0.4 3.5 1.7 9.8 2.9 1.7 2.2 8.4 2.8 0.9 0.4 3.0 2.4 4.0 27.0 2.5 2.6 6.5 1.0 0.2 3.1 10.8 9.2 27.7 1.4 0.4 3.6 3.5 0.6 2.5 2.3 1.2 3.9 1.3 2.9 5.9 2.0 2.6 47.0 2.6 1.3 2.1 23.9 1.6 1.7 1.0 2.4 2.3 14.3 7.2 2.5 11.6 0.1 4.0 36.8 13.8 0.7 1.2 4.3 2.1 4.8 1.7 1.4 1.1 1.1 7.2 0.9 0.7 1.1 1.3 3.6 2.6 3.5 1.6 0.9 17.4 1.5 2.8 1.5 9.3 5.4 3.8 5.8 2.3 0.6 5.0 4.9 0.6 4.9 2.2 2.6 2.0 2.9 14.7 0.4 4.7 2.0 8.6 1.3 3.7 7.6 1.5 6.0 0.6 3.4 3.8 1.4 5.1 2.4 2.3 4.0 5.1 1.1 3.6 3.6 3.6 1.2 8.3 1.9 5.7 0.7 13.3 2.3 4.9 13.8 13.9 1.2 1.7 0.9 0.0 0.9 1.0 4.0 0.1 0.4 0.3 36.8 0.7 0.3 0.4 0.2 4.3 0.4 1.7 1.7 2.2 1.0 0.2 1.4 0.4 1.2 1.0 LTB4R2 "BLT2, BLTR2, JULF2, NOP9" ENSG00000213906 "Leukotriene B4 receptor 2" Q9NPC1 14 24305734-24312053 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 38.9;lymphoid tissue: 26.8;skin 1: 21.4;tongue: 43.6" "Cell line enhanced" "Detected in many" "HaCaT: 15.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB022689, HPA029680, HPA072921" Uncertain Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "CAB022689: , HPA029680: AB_10603013, HPA072921: " "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (9.53e-2)" "unprognostic (8.82e-2)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-1)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (1.48e-3)" "unprognostic (7.18e-2)" "unprognostic (7.05e-11)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" "unprognostic (1.19e-1)" 1.5 1.2 0.4 1.8 0.5 4.8 1.1 0.4 0.6 7.9 0.4 0.6 0.8 2.4 1.0 4.7 38.9 0.8 0.7 0.4 0.5 0.1 6.1 0.5 1.1 1.8 0.4 0.7 0.7 0.5 0.3 0.7 0.8 0.5 1.8 0.3 0.5 4.7 1.1 0.9 21.4 1.8 0.4 0.4 3.5 1.0 1.4 0.4 3.1 0.9 43.6 26.8 0.6 9.0 0.3 2.2 1.4 2.0 0.9 2.7 1.1 2.4 4.3 1.8 1.8 0.4 0.6 7.6 0.9 0.4 1.3 0.9 3.4 1.5 3.2 1.6 0.6 15.7 1.3 2.7 0.9 3.9 4.8 2.2 3.5 1.6 0.5 3.6 4.1 0.5 3.6 1.9 2.3 0.6 2.7 3.5 0.6 4.8 1.9 3.8 1.0 5.4 7.8 1.7 1.8 0.4 3.1 3.4 1.6 1.6 2.0 1.3 3.7 2.7 1.6 2.6 3.2 4.0 1.3 7.9 2.2 5.2 0.5 6.0 2.0 0.0 2.0 1.4 2.7 1.6 1.6 0.1 2.2 2.0 2.2 0.3 1.7 0.9 1.3 0.9 0.8 0.6 0.4 1.1 0.4 0.5 0.4 0.6 0.5 0.1 0.4 0.7 0.5 0.4 MAS1L "dJ994E9.2, MAS-L, MRG" ENSG00000204687 "MAS1 proto-oncogene like, G protein-coupled receptor" P35410 6 29486697-29487956 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "cervix, uterine: 7.5;epididymis: 4.0" "Cell line enriched" "Detected in single" 39 "HEL: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA017983 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane, Cytosol" Nucleoplasm "HPA017983: AB_1849332" "unprognostic (3.66e-2)" "unprognostic (2.51e-1)" "unprognostic (2.30e-2)" "unprognostic (5.22e-2)" "unprognostic (1.65e-1)" 2.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 7.5 1.3 0.4 1.2 4.0 2.1 0.2 1.2 0.4 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.8 1.1 1.5 0.3 0.2 1.7 1.5 1.1 0.0 0.0 0.5 0.3 0.0 0.5 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MC2R ACTHR ENSG00000185231 "Melanocortin 2 receptor" Q01718 18 13882044-13915707 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 31.7;pituitary gland: 14.3" "Cell line enhanced" "Detected in some" "HeLa: 1.8;MCF7: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA079148 Enhanced "HPA079148: " "unprognostic (2.09e-1)" "unprognostic (3.63e-2)" "unprognostic (1.85e-2)" 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 14.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.1 0.1 1.3 0.3 0.1 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.3 1.1 0.2 0.0 0.1 0.3 0.1 0.2 0.0 0.0 0.4 0.3 0.1 0.9 0.1 0.0 0.5 0.0 1.8 0.2 0.0 0.2 0.0 0.0 0.9 0.0 0.6 0.0 0.1 0.4 0.0 3.7 0.0 0.0 0.6 0.1 0.2 0.5 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.2 0.3 0.5 0.0 0.2 0.2 0.0 0.1 0.4 0.0 1.3 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.5 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 MC3R MC3 ENSG00000124089 "Melanocortin 3 receptor" P41968 20 56248732-56249815 "G-protein coupled receptors, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 6.4" "Cell line enriched" "Detected in single" 24 "hTERT-HME1: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basal ganglia: 4.8;hypothalamus: 3.3;thalamus: 2.6" HPA074739 Uncertain "HPA074739: " 0.0 0.4 0.1 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MC4R ENSG00000166603 "Melanocortin 4 receptor" P32245 18 60371110-60372775 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.8;fallopian tube: 10.3" "Cell line enriched" "Detected in single" 69 "fHDF/TERT166: 45.9" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA016719 Uncertain "HPA016719: AB_1853617" "unprognostic (2.29e-1)" "unprognostic (5.31e-3)" "unprognostic (5.78e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.33e-1)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.49e-2)" "unprognostic (2.30e-1)" "unprognostic (2.59e-1)" 0.4 1.1 4.0 0.3 9.8 0.2 0.9 0.7 6.4 0.5 0.5 0.3 0.0 0.6 0.4 1.3 0.4 10.3 0.4 0.4 3.0 7.8 0.4 0.2 0.3 0.4 1.1 7.6 0.6 0.2 0.2 0.3 0.2 3.3 0.4 0.5 0.1 2.5 0.5 0.2 0.3 0.4 0.2 0.8 0.8 0.6 0.6 5.1 0.0 0.2 0.0 1.4 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 9.8 0.7 6.4 3.0 7.8 1.1 7.6 3.3 5.1 MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.9;esophagus: 2.7" "Cell line enhanced" "Detected in some" "HDLM-2: 2.1;SiHa: 1.7;U-138 MG: 6.1;U-2 OS: 1.4;U-2197: 1.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA042365 Approved "HPA042365: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 7.9 2.7 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.1 1.6 0.0 0.2 0.0 0.4 0.1 1.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 6.1 1.4 1.1 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 MRGPRD mrgD ENSG00000172938 "MAS related GPR family member D" Q8TDS7 11 68980021-68980986 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 2.5" "Cell line enhanced" "Detected in single" "U-2197: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031346 Uncertain "HPA031346: AB_10602710" "unprognostic (1.92e-1)" "unprognostic (7.14e-2)" "unprognostic (1.72e-1)" 0.4 0.4 0.0 0.3 0.0 0.5 0.1 2.0 0.0 0.9 2.5 0.0 1.8 0.0 0.9 0.9 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 2.2 0.0 0.1 0.8 1.1 0.0 0.0 0.5 0.3 0.0 0.0 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MRGPRE "GPR167, mrgE" ENSG00000184350 "MAS related GPR family member E" Q86SM8 11 3227698-3232386 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 9 "brain: 34.9" "Group enriched" "Detected in some" 6 "NB-4: 2.6;RPMI-8226: 4.9;SCLC-21H: 8.0" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.9" "Region enriched" "Detected in many" 14 "pons and medulla: 34.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046556 Uncertain "HPA046556: AB_10961404" "unprognostic (1.18e-1)" "unprognostic (7.52e-4)" "unprognostic (1.04e-1)" "unprognostic (9.09e-2)" "unprognostic (6.65e-2)" "unprognostic (1.77e-2)" "unprognostic (1.27e-1)" "unprognostic (1.83e-1)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" 0.1 0.8 0.1 0.1 0.3 2.1 0.8 1.5 2.0 3.5 0.8 0.0 0.0 0.0 2.0 0.7 0.6 1.7 0.5 1.1 0.6 2.3 0.1 0.0 0.3 0.0 2.5 0.0 0.1 0.3 0.0 0.5 1.8 34.9 1.1 0.0 3.9 1.6 1.3 0.1 0.3 0.3 0.5 1.5 1.9 0.1 0.2 0.1 0.0 0.9 0.2 0.0 0.6 1.6 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.9 0.0 0.0 8.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.1 0.3 1.5 2.0 0.6 2.3 2.5 0.0 34.9 0.1 MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013409 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 26.2;ASC TERT1: 11.7;BJ: 14.7;BJ hTERT+: 37.3;BJ hTERT+ SV40 Large T+: 14.0;U-2197: 17.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "cerebellum: 16.6" "Low region specificity" "Detected in all" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" 10.8 1.7 0.8 7.6 1.2 0.0 26.6 7.8 1.5 61.9 39.5 1.2 13.9 4.8 49.2 22.3 28.2 28.0 30.6 6.2 0.7 0.4 4.2 2.1 4.8 5.6 1.1 1.3 25.6 0.9 0.4 1.1 5.9 1.8 29.6 4.8 5.8 2.9 25.5 3.1 4.0 10.1 41.1 1.0 8.2 14.2 13.1 0.6 0.1 3.8 6.4 2.7 42.2 19.6 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 26.2 11.7 0.5 14.7 37.3 14.0 9.3 0.0 0.6 0.0 0.3 11.3 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.0 0.0 3.3 0.0 0.0 8.6 0.0 8.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 17.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 7.8 1.5 0.7 0.4 1.1 1.3 1.8 0.6 MRGPRG "GPR169, mrgG" ENSG00000182170 "MAS related GPR family member G" Q86SM5 11 3217944-3218813 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 8 "testis: 4.4" "Group enriched" "Detected in some" 4 "NB-4: 1.1;REH: 2.5;SCLC-21H: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058909 Uncertain "HPA058909: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MRGPRX2 MRGX2 ENSG00000183695 "MAS related GPR family member X2" Q96LB1 11 19054455-19060681 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 9.2" "Cell line enriched" "Detected in single" 4 "U-266/84: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "gdT-cell: 2.0" "Lineage enriched" "Detected in single" 21 "T-cells: 2.0" HPA055220 Approved "HPA055220: " "unprognostic (1.56e-2)" "unprognostic (1.79e-1)" 5.2 0.0 0.0 0.1 0.0 0.0 4.1 0.0 0.0 2.8 0.5 0.0 0.0 0.0 2.0 1.0 0.7 0.1 2.9 0.1 0.0 0.0 0.0 0.0 2.3 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.7 1.1 0.0 1.3 0.0 0.3 4.3 0.5 9.2 0.0 0.3 0.4 0.8 0.0 0.0 0.0 1.6 0.4 2.8 2.2 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MTNR1B ENSG00000134640 "Melatonin receptor 1B" P49286 11 92969720-92985066 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;lymphoid tissue: 1.9;placenta: 4.5;testis: 2.0" "Group enriched" "Detected in some" 8 "AF22: 1.1;U-138 MG: 1.4;WM-115: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "midbrain: 0.8;pons and medulla: 1.2" HPA074024 Supported "HPA074024: " "unprognostic (3.61e-1)" "unprognostic (1.43e-1)" 0.1 0.0 0.3 0.0 3.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.0 0.0 1.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NMBR "BB1, BB1R" ENSG00000135577 "Neuromedin B receptor" P28336 6 142058330-142088799 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.5;fallopian tube: 3.3;testis: 5.1" "Cell line enhanced" "Detected in some" "AN3-CA: 2.9;RPTEC TERT1: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026665 Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA026665: AB_1854527" "unprognostic (6.24e-2)" "unprognostic (3.05e-1)" "unprognostic (2.77e-2)" "unprognostic (7.88e-2)" "unprognostic (3.54e-2)" "unprognostic (8.21e-2)" "unprognostic (3.63e-2)" "unprognostic (1.54e-1)" "unprognostic (3.95e-1)" "unprognostic (7.94e-3)" "unprognostic (3.44e-1)" "unprognostic (2.11e-1)" "unprognostic (8.45e-2)" 0.1 0.0 0.6 0.0 2.5 0.0 0.4 0.0 0.8 0.5 0.0 0.0 0.2 0.3 0.6 3.3 0.0 0.0 0.5 1.6 0.2 0.0 0.2 0.0 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.2 0.8 0.1 0.2 5.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.9 0.9 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.5 0.0 0.4 0.0 0.2 1.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NMUR1 "FM-3, GPC-R, GPR66, NMU1R" ENSG00000171596 "Neuromedin U receptor 1" Q9HB89 2 231523160-231530495 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in some" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 6 "gdT-cell: 15.2;MAIT T-cell: 3.9;memory CD8 T-cell: 7.3;naive CD8 T-cell: 4.6;NK-cell: 8.1" "Group enriched" "Detected in many" 18 "NK-cells: 8.1;T-cells: 15.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA027895 Uncertain "HPA027895: AB_10602713" "unprognostic (1.11e-2)" "unprognostic (1.14e-2)" "unprognostic (6.74e-3)" "unprognostic (9.44e-3)" "unprognostic (2.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (3.13e-2)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" "unprognostic (1.22e-2)" "unprognostic (2.07e-1)" "unprognostic (4.08e-4)" "unprognostic (3.76e-3)" "unprognostic (2.26e-1)" "unprognostic (2.61e-1)" "unprognostic (5.25e-2)" 13.6 2.2 0.6 1.2 0.9 3.5 3.2 2.1 0.8 2.5 3.5 0.4 4.4 4.4 1.8 3.8 3.3 3.0 4.6 12.6 0.3 0.3 2.1 2.0 6.4 0.5 0.3 0.1 2.8 7.7 0.2 0.6 4.8 0.6 4.0 1.2 8.4 4.6 3.6 0.3 0.8 7.3 8.4 0.6 7.3 1.7 3.0 0.7 0.2 1.8 0.6 0.8 4.4 1.4 0.0 0.3 0.6 0.1 8.1 15.2 3.6 0.3 1.1 1.4 1.5 0.1 0.4 1.2 0.5 0.0 0.0 0.1 0.4 0.5 0.8 0.4 0.4 0.7 2.5 0.5 0.1 0.5 0.9 0.8 1.1 0.4 0.1 0.8 1.3 0.7 0.3 0.4 0.0 0.6 2.4 1.4 0.1 0.7 0.6 1.1 0.7 0.3 0.4 0.7 0.6 0.1 0.9 0.6 0.7 1.0 0.6 0.3 1.3 1.6 1.6 1.7 1.2 0.8 0.4 2.0 0.1 0.6 0.5 0.8 0.5 0.4 0.1 0.0 15.2 0.0 3.9 0.0 1.2 7.3 0.0 0.0 0.1 4.6 0.6 8.1 0.1 0.3 0.5 3.6 0.6 0.9 2.1 0.8 0.3 0.3 0.3 0.1 0.6 0.7 NMUR2 NMU2R ENSG00000132911 "Neuromedin U receptor 2" Q9GZQ4 5 152391532-152433368 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.9;stomach 1: 5.0;testis: 8.0" "Cell line enriched" "Detected in some" 8 "EFO-21: 14.5" "Group enriched" "Detected in some" 5 "colorectal cancer: 0.5;endometrial cancer: 0.6;pancreatic cancer: 1.8;stomach cancer: 2.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in all" "HPA027800, HPA045836" Enhanced Supported "Plasma membrane" "Plasma membrane" "HPA027800: , HPA045836: AB_10968856" "unprognostic (1.82e-1)" "unprognostic (3.83e-1)" "unprognostic (2.66e-1)" "unprognostic (9.29e-2)" "unprognostic (5.87e-2)" "unprognostic (6.44e-3)" "unprognostic (3.13e-1)" "unprognostic (6.47e-2)" "unprognostic (5.63e-2)" "unprognostic (8.20e-3)" "unprognostic (8.90e-5)" "unprognostic (1.48e-2)" "unprognostic (9.24e-2)" "unprognostic (9.56e-2)" "unprognostic (2.29e-1)" 0.1 0.5 0.6 0.7 1.0 0.0 0.1 0.2 1.2 0.4 0.2 0.7 1.1 0.6 0.9 0.2 0.4 0.1 0.6 1.4 0.9 2.8 2.0 0.1 2.9 0.1 4.3 0.4 0.1 0.0 0.0 0.7 0.5 1.6 0.2 0.4 0.0 0.0 0.2 0.8 0.0 0.3 0.2 8.9 0.0 5.0 8.0 1.4 0.9 2.5 0.0 0.3 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.7 14.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 1.8 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.2 1.2 0.9 2.8 4.3 0.4 1.6 1.4 NPFFR1 "GPR147, NPFF1R1, OT7T022" ENSG00000148734 "Neuropeptide FF receptor 1" Q9GZQ6 10 70247329-70283676 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "brain: 34.9" "Cell line enhanced" "Detected in some" "U-2 OS: 4.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.2" "Group enriched" "Detected in all" 5 "basal ganglia: 10.2;cerebellum: 34.9" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basal ganglia: 16.1;hypothalamus: 7.3" "Low region specificity" "Detected in many" HPA037521 Uncertain "HPA037521: " "unprognostic (1.73e-3)" "unprognostic (7.29e-4)" "unprognostic (2.12e-1)" "unprognostic (3.50e-2)" "unprognostic (2.07e-1)" "unprognostic (8.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.48e-1)" "unprognostic (4.14e-2)" "unprognostic (3.51e-1)" "unprognostic (9.62e-2)" "unprognostic (6.78e-2)" "unprognostic (5.84e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" 0.6 0.5 1.9 1.8 10.2 1.3 0.9 34.9 2.6 0.9 0.6 2.6 0.0 0.8 1.0 1.2 0.4 1.6 0.6 0.4 2.7 4.1 0.5 0.5 1.3 2.5 2.2 4.1 0.8 0.3 0.9 0.4 0.4 4.7 0.6 0.8 5.4 0.4 1.1 1.0 1.0 0.8 0.4 4.0 1.0 1.4 4.7 2.0 0.0 0.6 0.0 1.4 0.6 0.7 1.0 1.2 2.4 2.2 1.3 0.6 2.6 1.1 0.7 0.9 0.7 0.8 1.2 0.7 0.3 0.4 0.3 0.3 1.3 2.3 0.8 0.7 1.0 1.0 2.2 1.2 0.7 0.7 0.8 1.0 1.0 1.0 0.8 0.8 1.3 0.7 1.0 0.5 0.8 0.9 0.9 0.9 0.5 0.9 0.7 0.9 0.7 0.3 0.9 0.8 0.5 0.8 0.8 0.8 0.8 0.8 1.1 0.4 0.5 0.6 1.0 0.9 4.7 0.8 1.0 0.7 0.8 0.5 0.6 0.9 0.7 2.4 2.2 0.4 0.5 0.7 0.5 0.5 0.5 0.4 1.2 1.0 0.6 0.6 1.9 1.3 0.4 0.9 0.4 2.6 1.9 10.2 34.9 2.6 2.7 4.1 2.2 4.1 4.7 2.0 NPFFR2 "GPR74, NPFF2, NPGPR" ENSG00000056291 "Neuropeptide FF receptor 2" Q9Y5X5 4 72031804-72148067 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.4;seminal vesicle: 10.1" "Group enriched" "Detected in some" 10 "NTERA-2: 8.8;RPTEC TERT1: 11.4;SH-SY5Y: 13.5;U-2 OS: 13.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.3" "Low lineage specificity" "Detected in single" "Region enriched" "Detected in single" 4 "olfactory region: 5.3" "Low region specificity" "Detected in many" HPA026825 Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" "Plasma membrane" "Actin filaments" "HPA026825: AB_10603123" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (6.07e-2)" "unprognostic (4.68e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.51e-1)" "unprognostic (2.40e-5)" "unprognostic (5.75e-2)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-1)" 0.9 0.2 5.5 0.7 2.6 0.2 1.4 0.2 3.5 0.5 0.5 0.0 0.0 0.5 0.1 2.8 0.3 0.8 0.4 0.4 0.9 2.9 0.6 0.2 0.2 0.6 0.5 4.0 0.3 1.2 0.1 1.0 4.6 1.5 3.2 0.9 1.4 0.3 10.1 0.3 0.7 0.5 0.2 0.6 0.5 0.4 1.6 0.0 15.4 1.2 0.0 0.6 2.5 0.7 0.6 0.3 2.3 0.3 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 11.4 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.2 0.4 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.6 0.2 0.2 1.1 0.8 0.3 0.3 0.2 0.1 5.5 2.6 0.2 3.5 0.9 2.9 0.5 4.0 1.5 0.0 NPY1R NPYR ENSG00000164128 "Neuropeptide Y receptor Y1" P25929 4 163323961-163344832 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.2" "Cell line enriched" "Detected in some" 18 "HEL: 50.2" "Cancer enriched" "Detected in many" 13 "breast cancer: 65.2" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029903 Approved Nucleoplasm,Mitochondria,Cytosol "Mitochondria, Cytosol" Nucleoplasm "HPA029903: AB_10601276" "prognostic favourable (7.68e-5)" "unprognostic (9.14e-3)" "unprognostic (1.55e-1)" "unprognostic (5.09e-2)" "unprognostic (2.60e-1)" "unprognostic (9.29e-2)" "unprognostic (5.28e-3)" "unprognostic (2.26e-1)" "unprognostic (4.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.89e-2)" "unprognostic (5.92e-2)" "unprognostic (7.39e-2)" "unprognostic (1.92e-3)" "unprognostic (5.48e-2)" "unprognostic (1.74e-1)" "unprognostic (2.21e-1)" 18.0 15.9 5.2 1.5 17.1 0.2 17.5 0.9 11.4 6.2 3.1 0.7 3.9 0.7 5.0 5.4 2.3 4.3 2.4 2.6 7.1 4.2 16.6 8.3 1.2 7.2 1.5 5.8 1.8 14.5 1.1 3.9 2.7 3.5 1.9 2.4 2.0 11.0 4.5 1.5 5.0 0.9 3.1 3.7 55.2 1.2 2.7 6.0 0.0 4.4 1.4 0.6 3.4 3.3 0.5 0.3 1.2 0.4 0.3 1.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 50.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.6 0.0 1.9 0.7 0.4 1.2 0.5 0.1 0.6 0.4 0.7 0.9 0.0 0.5 0.7 1.2 1.1 0.3 0.2 0.3 0.3 0.0 5.2 17.1 0.9 11.4 7.1 4.2 1.5 5.8 3.5 6.0 NPY4R "PP1, PPYR1, Y4" ENSG00000204174 "Neuropeptide Y receptor Y4" P50391 10 46461099-46465881 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 9.4;skin 1: 4.3" "Cell line enriched" "Detected in some" 5 "A549: 24.9" "Cancer enhanced" "Detected in single" "prostate cancer: 0.8" "Group enriched" "Detected in some" 5 "cerebellum: 1.6;cerebral cortex: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA027863 Approved "HPA027863: AB_10602819" "unprognostic (2.26e-6)" "unprognostic (2.94e-1)" "unprognostic (8.17e-2)" "unprognostic (1.20e-1)" "unprognostic (1.30e-1)" "unprognostic (1.77e-3)" "unprognostic (1.98e-1)" "unprognostic (2.64e-3)" "unprognostic (6.58e-2)" "unprognostic (9.79e-2)" 0.2 0.0 0.2 0.7 0.2 0.0 0.2 1.6 1.2 0.3 7.4 0.2 0.2 2.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.8 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 1.9 9.4 0.2 0.2 0.2 0.2 4.3 2.6 1.4 0.2 0.2 2.4 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 24.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.0 0.7 0.0 5.1 0.0 0.4 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.6 1.2 0.2 0.2 0.2 0.2 0.2 0.2 NTSR1 NTR ENSG00000101188 "Neurotensin receptor 1" P30989 20 62708837-62762771 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.0;intestine: 15.1" "Cell line enriched" "Detected in some" 5 "PC-3: 35.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA050299 Supported "Plasma membrane" "Plasma membrane" "HPA050299: " "unprognostic (4.14e-2)" "unprognostic (2.02e-2)" "unprognostic (2.75e-2)" "unprognostic (8.87e-4)" "unprognostic (9.27e-3)" "unprognostic (1.45e-1)" "unprognostic (4.17e-2)" "unprognostic (2.80e-3)" "unprognostic (7.16e-2)" "unprognostic (3.10e-3)" "unprognostic (3.55e-2)" "unprognostic (2.53e-1)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" 0.3 0.1 3.7 2.5 3.6 3.8 0.1 0.1 7.0 0.1 15.1 0.0 0.0 0.4 0.2 0.1 0.1 0.1 1.4 0.1 2.0 1.1 0.6 0.2 0.3 0.3 3.3 1.0 0.4 0.1 0.2 0.3 0.2 1.4 0.2 0.5 1.2 0.3 0.1 0.2 0.2 1.5 0.8 0.8 0.6 0.5 0.5 0.0 0.0 0.1 0.3 0.1 0.3 0.1 0.0 0.3 0.0 0.3 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.2 6.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 1.6 0.1 1.5 0.2 35.0 1.0 0.0 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.3 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.7 3.6 0.1 7.0 2.0 1.1 3.3 1.0 1.4 0.0 OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772491-128775790 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 11.4;retina: 23.9" "Cell line enhanced" "Detected in many" "U-87 MG: 36.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytokinetic bridge,Cytosol" Nucleoplasm "Nuclear bodies, Cytokinetic bridge, Cytosol" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavourable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavourable (2.26e-8)" "prognostic unfavourable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavourable (9.33e-4)" 0.9 1.8 0.7 3.7 0.9 1.7 0.7 1.0 2.3 0.7 2.2 0.7 0.7 0.5 2.6 0.7 2.4 0.8 4.2 11.4 0.7 0.8 0.7 0.7 0.9 1.0 0.7 1.3 0.7 0.7 0.0 0.7 0.7 0.7 1.4 0.0 23.9 1.1 0.7 1.9 0.9 0.9 0.7 0.7 1.1 1.4 1.1 0.7 0.7 2.3 0.7 0.7 4.3 0.7 0.5 1.2 0.6 1.4 0.0 1.4 0.3 1.6 2.2 5.1 1.7 0.0 0.0 1.5 9.6 0.0 0.0 0.0 5.0 2.0 2.5 1.4 0.0 1.4 0.0 0.0 0.0 0.3 3.6 1.5 3.0 2.5 0.0 1.9 1.5 0.0 0.0 0.0 0.0 0.0 2.2 0.6 1.0 0.7 2.0 3.5 4.6 2.9 1.0 5.3 2.9 0.0 0.6 0.7 6.8 2.3 5.2 4.3 0.5 1.9 4.0 9.8 1.0 7.6 8.6 2.0 2.1 1.5 36.9 4.5 9.1 0.0 0.3 0.6 1.4 1.4 0.9 0.2 0.8 1.0 1.2 0.5 0.3 0.9 0.0 0.0 1.0 0.7 0.4 0.3 0.7 0.9 1.0 0.9 0.7 0.8 0.7 1.3 0.7 0.7 OPN3 "ECPN, encephalopsin, ERO, NMO-1, PPP1R116" ENSG00000054277 "Opsin 3" Q9H1Y3 1 241590102-241677376 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 12.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 12.1" "Low region specificity" "Detected in all" "CAB013682, HPA064443" Uncertain Approved Nucleoplasm Nucleoplasm "CAB013682: , HPA064443: " "unprognostic (2.41e-2)" "prognostic unfavourable (3.17e-5)" "unprognostic (1.75e-2)" "unprognostic (1.93e-1)" "prognostic unfavourable (1.70e-4)" "unprognostic (7.12e-2)" "unprognostic (5.10e-3)" "unprognostic (1.24e-2)" "unprognostic (2.39e-1)" "unprognostic (4.96e-1)" "unprognostic (2.66e-2)" "unprognostic (3.44e-1)" "unprognostic (9.13e-2)" "unprognostic (9.15e-3)" "unprognostic (2.61e-2)" "unprognostic (7.12e-2)" "unprognostic (9.44e-3)" 5.3 4.2 5.1 4.5 8.8 1.7 6.4 1.9 22.1 4.4 9.0 2.4 1.0 2.6 6.2 6.7 7.9 6.7 4.6 3.5 5.2 4.9 6.2 18.1 11.8 8.4 5.0 11.1 6.8 4.2 1.8 6.9 26.4 3.4 2.3 8.0 1.4 4.1 2.3 2.6 4.1 4.4 2.9 3.2 7.8 5.6 4.7 1.7 12.5 9.3 1.7 7.1 6.2 5.1 2.5 12.1 0.9 1.4 0.5 0.5 0.6 2.1 7.0 5.1 0.4 18.8 35.9 3.9 3.7 2.8 2.7 2.7 0.5 5.9 0.3 0.2 4.5 12.3 1.6 2.6 2.7 7.7 0.4 0.0 1.6 4.3 9.6 1.7 4.0 18.1 7.4 1.6 4.1 5.4 3.5 1.0 4.3 1.1 0.6 2.2 13.9 3.8 2.9 0.3 6.7 18.4 3.1 1.4 5.2 2.4 7.5 2.0 0.4 6.8 6.5 0.6 0.5 1.0 3.9 2.5 3.9 0.3 2.0 5.7 7.9 0.0 1.1 0.9 0.1 1.4 0.1 2.2 0.2 0.2 2.7 2.5 0.3 0.5 0.3 0.5 1.2 12.1 0.2 0.6 5.1 8.8 1.9 22.1 5.2 4.9 5.0 11.1 3.4 1.7 OPN4 "melanopsin, MOP" ENSG00000122375 "Opsin 4" Q9UHM6 10 86654557-86666848 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Biological rhythms, Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.2;skeletal muscle: 14.6" "Cell line enhanced" "Detected in single" "PC-3: 1.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 21.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039147 Approved "HPA039147: AB_10673304" "unprognostic (3.67e-3)" "unprognostic (1.40e-2)" "unprognostic (3.02e-2)" "unprognostic (1.62e-1)" "unprognostic (7.03e-3)" "unprognostic (2.89e-2)" "unprognostic (3.26e-1)" "unprognostic (9.54e-2)" "unprognostic (5.68e-2)" "unprognostic (8.88e-3)" "unprognostic (1.93e-6)" "unprognostic (4.10e-2)" "unprognostic (5.58e-2)" "unprognostic (6.76e-2)" 3.5 0.3 5.4 0.4 21.2 0.2 1.1 0.0 5.1 0.6 0.9 0.0 0.0 0.5 0.4 0.4 0.6 0.4 0.5 3.1 3.0 0.1 0.3 0.2 0.3 0.2 0.2 3.3 0.3 0.4 3.6 0.6 0.5 0.0 0.2 0.7 1.2 1.6 0.2 14.6 1.2 1.1 0.5 0.0 0.3 0.5 0.5 2.0 0.0 1.4 2.7 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 21.2 0.0 3.5 3.0 0.1 0.2 3.3 0.0 2.0 OPN5 "dJ402H5.1, neuropsin, TMEM13" ENSG00000124818 "Opsin 5" Q6U736 6 47781982-47832780 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 7.3" "Cell line enhanced" "Detected in some" "Karpas-707: 1.0;SK-BR-3: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA026084 Supported "HPA026084: " "unprognostic (1.95e-1)" "unprognostic (6.18e-2)" "unprognostic (4.84e-1)" "unprognostic (1.07e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPRD1 ENSG00000116329 "Opioid receptor delta 1" P41143 1 28812142-28871267 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7" "Group enriched" "Detected in some" 12 "RH-30: 14.5;SCLC-21H: 5.7;SH-SY5Y: 5.8;WM-115: 19.3" "Cancer enhanced" "Detected in single" "melanoma: 1.0" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070831 Approved "HPA070831: " "unprognostic (1.44e-1)" "unprognostic (4.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.89e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-3)" "unprognostic (6.28e-3)" "unprognostic (5.92e-2)" "unprognostic (1.82e-2)" "unprognostic (5.95e-3)" "unprognostic (4.28e-3)" "unprognostic (2.98e-1)" "unprognostic (1.52e-7)" "unprognostic (1.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (2.18e-3)" 0.4 2.4 5.5 0.6 3.9 1.9 0.4 0.4 8.7 0.4 0.6 0.0 0.0 0.5 0.4 0.4 0.4 0.4 0.6 0.4 3.0 1.3 0.4 0.4 0.5 0.7 0.6 5.9 0.5 1.3 0.2 0.5 0.5 4.7 0.4 0.5 0.1 1.0 0.2 3.2 1.0 0.6 0.4 0.4 0.7 0.8 0.8 0.2 0.0 0.6 0.0 0.2 0.4 0.4 1.2 1.1 3.1 0.5 1.1 0.7 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.2 0.9 0.0 0.0 14.5 0.1 0.0 0.0 5.7 5.8 0.0 0.1 0.9 0.1 0.1 0.0 0.1 0.3 0.2 0.0 0.2 0.0 0.2 0.1 0.3 19.3 3.1 0.5 0.6 0.6 0.3 0.4 0.6 0.6 0.5 0.1 1.2 0.6 0.7 2.5 1.1 0.3 1.1 0.3 0.1 5.5 3.9 0.4 8.7 3.0 1.3 0.6 5.9 4.7 0.2 OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225716-53251697 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.0;prostate: 6.7" "Cell line enriched" "Detected in some" 5 "U-937: 21.6" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: " "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (8.70e-3)" "unprognostic (3.73e-2)" "unprognostic (6.74e-2)" "unprognostic (2.22e-3)" "unprognostic (8.09e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-4)" "unprognostic (1.61e-1)" 0.7 0.7 15.9 0.3 18.0 0.4 0.3 2.2 8.8 0.4 0.4 0.3 0.0 0.4 0.4 0.6 0.5 0.7 0.4 0.8 4.5 6.2 0.3 0.5 0.8 0.4 1.7 5.8 0.4 0.3 0.4 0.8 2.8 3.1 6.7 0.4 0.0 0.3 0.4 3.8 0.4 0.5 0.5 0.5 0.6 0.3 2.8 1.6 0.2 0.9 0.0 0.3 0.3 0.1 0.2 0.8 1.2 0.2 0.1 0.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 21.6 0.1 1.2 0.2 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.1 0.1 0.8 0.0 0.0 15.9 18.0 2.2 8.8 4.5 6.2 1.7 5.8 3.1 1.6 OPRM1 MOR1 ENSG00000112038 "Opioid receptor mu 1" P35372 6 154010496-154246867 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 37.9" "Cell line enriched" "Detected in single" 24 "SH-SY5Y: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 37.9" "Cell type enhanced" "Detected in single" "neutrophil: 2.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014509, HPA067435" Enhanced Supported "HPA014509: AB_1854801, HPA067435: " "unprognostic (7.34e-2)" "unprognostic (6.91e-2)" 0.5 3.4 7.0 0.6 17.5 1.8 0.9 37.9 7.6 0.5 0.6 0.8 0.0 0.6 0.7 1.4 3.7 0.5 1.0 0.5 2.6 2.3 0.5 0.5 0.5 0.9 0.6 9.3 0.8 0.7 0.4 0.6 0.5 5.2 0.7 0.4 0.0 0.6 0.2 0.9 1.8 0.5 0.3 1.9 0.6 1.0 8.0 0.5 0.0 1.0 0.0 0.3 0.5 0.5 0.5 0.2 2.1 0.1 0.1 0.7 0.0 0.1 0.0 0.2 0.4 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.2 0.4 0.4 0.1 0.0 0.3 0.3 0.2 0.1 0.2 0.1 0.1 0.4 0.1 0.0 0.3 0.5 0.1 0.5 0.0 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.1 0.3 12.8 0.0 0.0 0.3 0.3 0.1 0.3 0.4 0.1 0.3 0.1 0.4 0.2 0.1 0.3 0.1 0.0 0.2 0.1 0.6 0.6 0.0 0.7 0.2 0.3 0.5 0.1 0.5 0.4 0.1 2.1 0.1 0.0 0.2 0.3 0.0 7.0 17.5 37.9 7.6 2.6 2.3 0.6 9.3 5.2 0.5 OXER1 "GPCR, GPR170, TG1019" ENSG00000162881 "Oxoeicosanoid receptor 1" Q8TDS5 2 42762481-42764261 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 42.9;liver: 26.9" "Cell line enhanced" "Detected in some" "CACO-2: 8.8;Hep G2: 9.8;HMC-1: 8.4;REH: 4.2;THP-1: 3.8" "Cancer enhanced" "Detected in all" "liver cancer: 12.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 17.4;eosinophil: 42.9" "Lineage enriched" "Detected in single" 76 "granulocytes: 42.9" HPA051433 Uncertain "HPA051433: " "unprognostic (6.77e-2)" "unprognostic (4.20e-2)" "unprognostic (3.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.09e-3)" "unprognostic (4.45e-3)" "unprognostic (7.80e-2)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-3)" "unprognostic (5.39e-2)" "unprognostic (1.82e-3)" "unprognostic (5.83e-2)" "unprognostic (1.66e-1)" "unprognostic (4.89e-2)" "unprognostic (5.46e-2)" 8.2 0.7 0.7 1.2 0.7 2.0 0.9 0.7 1.5 1.9 2.1 0.7 0.7 4.9 1.7 2.9 1.1 1.4 1.1 2.0 1.5 0.3 4.1 26.9 9.1 4.1 0.7 0.7 5.4 3.8 0.4 2.0 2.7 1.3 3.4 1.6 3.3 3.4 1.7 2.1 2.9 8.3 0.7 0.7 6.4 1.6 1.1 2.7 3.8 1.6 2.2 1.6 2.5 4.8 0.0 0.4 42.9 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 8.8 0.0 0.2 0.1 0.0 0.0 1.4 0.0 0.2 0.0 0.5 2.9 0.0 9.8 0.1 0.2 8.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 1.9 0.0 4.2 1.4 0.1 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 17.4 0.5 42.9 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.2 0.7 0.7 0.7 1.5 1.5 0.3 0.7 0.7 1.3 2.7 OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "kidney: 7.0" "Cell line enhanced" "Detected in some" "RT4: 7.6;SK-BR-3: 3.5;T-47d: 1.7;U-2 OS: 4.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 5 "myeloid DC: 2.9;plasmacytoid DC: 5.2" "Lineage enriched" "Detected in single" 6 "dendritic cells: 5.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" "Plasma membrane" "HPA067673: " "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" 2.1 0.0 0.7 1.7 0.2 0.0 6.7 0.0 2.0 1.6 3.0 0.1 0.6 4.0 3.2 2.5 0.0 0.0 0.8 0.8 7.0 0.0 0.5 0.0 0.7 0.0 0.6 0.0 0.3 1.2 0.5 2.4 4.9 0.3 0.1 4.3 0.5 0.5 1.6 0.3 0.1 0.0 0.8 0.9 1.8 0.9 0.0 5.2 0.1 0.5 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.6 0.0 0.2 0.0 3.5 0.0 1.7 0.0 0.0 0.0 4.0 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.5 0.1 0.0 0.1 0.8 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.1 0.0 0.0 5.2 0.0 0.1 P2RY1 "P2Y1, SARCC" ENSG00000169860 "Purinergic receptor P2Y1" P47900 3 152834693-152841439 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.1;placenta: 24.7" "Cell line enriched" "Detected in some" 5 "HEL: 29.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 29.1" "Group enriched" "Detected in some" 5 "basophil: 7.0;non-classical monocyte: 4.1" "Group enriched" "Detected in many" 6 "granulocytes: 7.0;monocytes: 4.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA015577 Enhanced "HPA015577: AB_1854882" "unprognostic (3.30e-1)" "unprognostic (4.52e-2)" "unprognostic (2.68e-2)" "unprognostic (4.76e-2)" "unprognostic (9.70e-2)" "unprognostic (1.40e-3)" "unprognostic (3.32e-2)" "unprognostic (2.53e-1)" "unprognostic (5.14e-1)" "unprognostic (2.58e-1)" "unprognostic (4.68e-2)" "unprognostic (2.70e-1)" "prognostic unfavourable (2.04e-7)" "unprognostic (1.36e-1)" "unprognostic (8.98e-2)" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" 2.9 1.7 4.7 5.9 29.1 4.8 2.0 3.1 6.3 6.7 8.7 4.9 0.6 3.3 8.5 0.8 19.4 2.3 2.2 2.9 8.4 2.3 1.1 1.6 10.4 2.1 1.8 6.1 9.6 3.6 0.5 2.3 24.7 2.4 8.0 6.9 2.6 5.6 2.6 7.1 8.8 6.1 4.8 3.8 2.4 1.7 1.3 3.3 3.0 1.5 9.9 3.5 3.0 9.5 0.0 0.9 7.0 4.1 0.0 0.0 0.2 0.0 0.5 4.7 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.4 5.8 0.0 0.0 0.5 0.0 1.0 2.6 0.8 0.2 0.0 2.3 29.6 0.0 0.0 0.0 3.4 2.7 0.4 5.8 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.5 0.1 4.3 3.6 0.0 0.1 0.8 0.0 2.0 0.7 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.5 1.2 0.0 2.5 0.0 0.0 0.0 3.0 0.0 3.4 7.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 4.1 0.9 0.0 0.2 4.7 29.1 3.1 6.3 8.4 2.3 1.8 6.1 2.4 3.3 P2RY10 P2Y10 ENSG00000078589 "P2Y receptor family member 10" O00398 X 78945332-78961954 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 51.6;lymphoid tissue: 47.0" "Cell line enriched" "Detected in some" 5 "Karpas-707: 52.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "basophil: 51.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036757, HPA065766" Enhanced "HPA036757: AB_10696786, HPA065766: " "unprognostic (3.02e-3)" "unprognostic (1.47e-3)" "unprognostic (1.50e-6)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.13e-4)" "unprognostic (3.33e-2)" "unprognostic (8.30e-2)" "unprognostic (1.13e-2)" "unprognostic (4.13e-3)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" "prognostic unfavourable (3.63e-4)" "unprognostic (2.23e-1)" "unprognostic (6.54e-2)" "unprognostic (3.85e-2)" "unprognostic (3.99e-2)" 1.9 0.5 0.4 19.1 0.5 5.7 1.0 0.4 0.4 1.4 3.8 0.0 0.1 1.7 1.0 0.5 2.6 0.8 2.2 0.8 0.5 0.5 1.4 1.0 6.2 47.0 0.5 0.0 1.1 0.5 0.0 0.6 0.1 0.1 0.9 2.5 0.8 3.9 0.3 0.5 0.8 11.0 0.4 0.7 31.2 2.3 0.5 0.0 23.3 1.5 1.8 30.0 9.9 1.3 19.3 0.9 51.6 2.3 4.0 9.7 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.6 0.0 0.1 0.0 51.6 0.0 36.8 3.2 0.2 2.9 17.8 7.3 6.4 0.9 19.3 6.8 5.0 6.8 4.0 2.3 0.7 9.7 3.2 0.4 0.5 0.4 0.4 0.5 0.5 0.5 0.0 0.1 0.0 P2RY11 P2Y11 ENSG00000244165 "Purinergic receptor P2Y11" Q96G91 19 10111538-10115372 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 20.1;NB-4: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 6.8;MAIT T-cell: 16.4;memory CD8 T-cell: 6.9;naive CD8 T-cell: 5.4;NK-cell: 10.7" "Group enriched" "Detected in all" 6 "NK-cells: 10.7;T-cells: 16.4" HPA014232 Approved "HPA014232: AB_1854883" "unprognostic (1.13e-1)" "unprognostic (3.12e-2)" "unprognostic (2.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.82e-1)" "unprognostic (2.79e-2)" "unprognostic (2.34e-1)" "unprognostic (5.56e-2)" "unprognostic (2.23e-1)" "unprognostic (1.93e-1)" "unprognostic (2.04e-3)" "unprognostic (2.22e-2)" "unprognostic (4.32e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (1.58e-1)" "prognostic favourable (1.77e-4)" 9.0 3.6 4.8 21.7 6.7 8.5 4.9 5.5 6.5 3.1 9.4 6.0 3.4 7.8 3.2 3.2 4.4 5.3 3.5 3.8 5.1 4.6 2.9 4.9 13.6 11.1 3.2 2.3 4.3 6.3 1.5 4.2 3.4 4.0 5.0 1.8 5.0 7.6 2.5 6.6 9.0 9.2 2.8 4.9 13.4 5.1 4.9 2.5 7.5 5.2 2.6 22.8 2.9 3.1 1.5 1.2 2.1 2.1 10.7 16.4 4.3 3.6 3.4 1.2 3.9 1.6 1.3 6.6 1.5 0.6 0.7 1.2 4.0 1.8 6.3 2.2 0.3 5.2 1.0 3.0 0.1 3.1 20.1 5.6 5.0 2.4 2.2 2.9 9.5 2.2 2.4 1.1 1.7 0.4 2.7 8.3 0.7 5.2 4.4 21.0 7.5 4.2 6.7 2.3 3.6 1.2 4.6 4.7 7.7 0.9 2.6 8.2 2.1 8.3 1.3 4.3 2.0 7.6 2.8 17.0 12.2 2.3 3.0 12.5 3.8 2.1 1.9 0.3 6.8 2.1 16.4 1.5 1.5 6.9 1.2 1.0 1.2 5.4 0.4 10.7 1.4 0.7 1.8 4.3 4.8 6.7 5.5 5.2 5.1 4.6 3.2 2.3 4.0 2.5 P2RY12 "HORK3, P2Y12, SP1999" ENSG00000169313 "Purinergic receptor P2Y12" Q9H244 3 151337380-151384812 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.0" "Cell line enhanced" "Detected in some" "HSkMC: 1.7;Karpas-707: 1.1;REH: 1.9" "Cancer enriched" "Detected in many" 14 "glioma: 17.3" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 12.4" "Group enriched" "Detected in many" 13 "dendritic cells: 5.0;monocytes: 12.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013796, HPA014518" Enhanced "HPA013796: AB_1854884, HPA014518: " "unprognostic (2.39e-2)" "unprognostic (1.60e-3)" "unprognostic (5.93e-2)" "unprognostic (1.77e-1)" "unprognostic (2.41e-2)" "unprognostic (2.52e-2)" "unprognostic (8.09e-2)" "unprognostic (1.72e-3)" "unprognostic (6.46e-2)" "unprognostic (8.64e-4)" "unprognostic (4.84e-2)" "unprognostic (5.96e-2)" "unprognostic (2.03e-1)" "unprognostic (8.92e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-2)" "unprognostic (4.04e-1)" 7.4 4.3 15.3 2.2 14.2 0.8 4.3 2.3 46.0 2.0 2.0 13.4 0.0 1.6 1.1 1.1 1.7 3.2 2.7 1.8 14.3 11.6 1.1 2.7 2.9 9.2 21.1 10.0 2.2 0.9 2.0 0.9 2.7 16.8 1.4 1.8 0.2 3.1 2.9 0.6 0.8 3.1 2.1 24.9 5.3 1.5 0.6 18.8 0.0 0.9 0.0 8.6 1.9 0.9 0.6 5.0 0.3 12.4 0.0 0.0 2.0 0.0 0.0 0.2 0.2 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.3 0.3 0.0 2.9 0.0 0.0 12.4 0.0 0.6 0.0 0.0 5.0 0.6 0.0 0.0 0.3 0.0 3.3 0.5 0.0 2.0 15.3 14.2 2.3 14.6 14.3 11.6 21.1 10.0 16.8 18.8 P2RY13 "FKSG77, GPR86, GPR94, P2Y13" ENSG00000181631 "Purinergic receptor P2Y13" Q9BPV8 3 151326312-151329548 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 88.4;lymphoid tissue: 44.1" "Cell line enhanced" "Detected in some" "HEK 293: 1.1;U-937: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 88.4" "Group enriched" "Detected in many" 6 "granulocytes: 88.4;monocytes: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049047 Enhanced "HPA049047: " "unprognostic (1.09e-3)" "unprognostic (7.51e-4)" "unprognostic (1.68e-2)" "unprognostic (2.37e-3)" "unprognostic (3.95e-2)" "unprognostic (8.66e-3)" "unprognostic (7.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.84e-3)" "unprognostic (1.83e-1)" "unprognostic (4.97e-2)" "unprognostic (1.17e-1)" "unprognostic (4.05e-1)" "unprognostic (4.46e-1)" "unprognostic (5.95e-2)" "unprognostic (2.21e-3)" "unprognostic (3.78e-1)" 4.0 2.6 5.1 13.4 6.1 15.1 2.7 1.7 8.2 1.7 2.8 13.8 0.1 3.0 1.5 2.2 2.1 2.1 2.5 1.7 4.9 4.7 1.8 5.1 5.0 35.1 7.1 3.4 1.3 2.1 1.0 1.7 3.2 8.1 2.1 4.2 2.0 1.9 2.1 1.3 1.6 7.4 3.5 8.2 44.1 1.8 1.2 5.1 2.0 1.5 1.1 5.5 3.8 1.5 0.2 10.1 88.4 26.1 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 0.2 0.2 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.2 0.8 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 1.1 0.1 0.1 23.6 20.3 0.0 23.5 0.0 0.2 0.0 0.0 10.1 0.0 0.0 0.0 88.4 0.0 26.1 0.1 0.0 10.2 5.1 6.1 1.7 8.2 4.9 4.7 7.1 3.4 8.1 5.1 P2RY14 "GPR105, KIAA0001" ENSG00000174944 "Purinergic receptor P2Y14" Q15391 3 151212117-151278467 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood: 54.9" "Cell line enriched" "Detected in single" 73 "HMC-1: 39.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "eosinophil: 54.9;plasmacytoid DC: 24.4" "Group enriched" "Detected in many" 8 "dendritic cells: 24.4;granulocytes: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022646 Uncertain "CAB022646: " "unprognostic (9.78e-2)" "unprognostic (7.47e-4)" "unprognostic (3.89e-2)" "unprognostic (4.52e-4)" "unprognostic (1.69e-2)" "unprognostic (2.57e-5)" "unprognostic (2.68e-2)" "unprognostic (1.55e-2)" "unprognostic (2.65e-1)" "unprognostic (1.64e-3)" "unprognostic (6.30e-2)" "unprognostic (2.45e-1)" "prognostic unfavourable (1.72e-5)" "unprognostic (3.79e-2)" "unprognostic (6.89e-2)" "unprognostic (1.58e-1)" "unprognostic (2.58e-2)" 14.3 0.9 3.9 9.0 6.9 0.5 6.1 1.9 3.8 5.2 17.6 1.3 1.3 5.7 7.2 9.4 17.6 1.2 4.4 4.4 4.3 3.0 2.1 0.7 8.5 7.1 5.0 2.8 1.8 0.9 2.2 4.7 25.9 3.7 10.4 8.3 11.2 2.1 1.1 4.2 2.8 16.3 15.8 2.3 4.4 17.2 2.1 4.2 4.7 3.6 8.9 5.3 21.4 1.7 4.9 24.4 54.9 0.1 2.8 5.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.1 54.9 0.2 0.0 5.0 0.8 0.1 0.5 3.3 4.9 0.0 0.0 2.2 2.8 0.0 24.4 0.2 0.5 3.9 6.9 1.9 3.8 4.3 3.0 5.0 2.8 3.7 4.2 P2RY2 P2U ENSG00000175591 "Purinergic receptor P2Y2" P41231 11 73218298-73236352 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 28.1;skeletal muscle: 29.5" "Cell line enhanced" "Detected in many" "HaCaT: 16.1;HL-60: 15.2;MCF7: 12.1;NB-4: 12.4;PC-3: 12.6;SK-BR-3: 14.0;THP-1: 35.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "eosinophil: 28.1" "Group enriched" "Detected in many" 12 "granulocytes: 28.1;monocytes: 10.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB022642 Uncertain Uncertain Cytosol Cytosol "CAB022642: " "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (6.50e-4)" "unprognostic (2.04e-2)" "unprognostic (4.66e-3)" "unprognostic (8.93e-2)" "unprognostic (2.87e-1)" "unprognostic (4.17e-2)" "prognostic unfavourable (2.19e-5)" "unprognostic (9.69e-2)" "unprognostic (4.92e-4)" "unprognostic (1.34e-1)" "unprognostic (2.82e-1)" "unprognostic (1.05e-1)" "unprognostic (8.57e-3)" 0.4 2.3 0.9 1.4 1.2 10.8 1.3 0.3 1.1 5.5 3.1 1.1 0.3 2.2 1.3 2.3 20.0 1.2 2.8 11.7 0.6 0.3 0.9 2.6 2.9 1.5 1.2 0.6 1.7 1.7 6.1 1.1 10.3 1.0 1.7 2.4 3.3 4.0 1.6 29.5 3.4 10.8 0.4 0.4 6.6 0.6 0.7 0.6 0.6 20.2 20.6 12.8 2.1 10.9 0.0 1.6 28.1 10.4 0.0 0.0 1.2 3.5 3.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 8.2 2.8 0.0 5.5 0.2 16.1 0.4 7.5 0.0 0.0 0.3 1.2 0.2 1.5 0.0 15.2 0.0 0.0 3.5 1.2 0.2 0.7 0.6 0.0 0.0 12.1 0.0 12.4 0.2 12.6 0.0 0.0 0.5 1.2 8.6 0.0 0.0 0.2 14.0 0.0 6.5 35.6 5.2 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 2.7 0.0 0.2 3.4 28.1 0.0 10.4 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 6.2 0.0 0.0 1.2 0.9 1.2 0.3 1.1 0.6 0.3 1.2 0.6 1.0 0.6 P2RY4 "NRU, P2P, P2Y4, UNR" ENSG00000186912 "Pyrimidinergic receptor P2Y4" P51582 X 70258170-70259764 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 14.2" "Cell line enhanced" "Detected in some" "Hep G2: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB022644 Uncertain "CAB022644: " "unprognostic (4.59e-2)" "unprognostic (4.23e-1)" "unprognostic (7.10e-2)" "unprognostic (1.69e-1)" "unprognostic (9.53e-4)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (6.77e-2)" "unprognostic (2.43e-1)" "unprognostic (2.09e-1)" "unprognostic (8.89e-3)" "unprognostic (2.90e-2)" "unprognostic (3.72e-2)" "unprognostic (3.61e-2)" "unprognostic (1.50e-2)" "unprognostic (3.89e-1)" 0.3 0.1 0.2 0.2 0.2 0.1 0.4 0.2 0.2 2.1 2.9 0.2 0.2 0.7 0.2 0.6 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.3 1.6 0.2 0.6 0.2 0.2 2.1 14.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.4 0.2 0.4 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.8 0.3 0.5 0.0 0.2 0.4 0.1 0.3 0.1 0.6 0.0 0.0 0.3 0.0 0.2 0.3 0.0 0.5 1.8 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 1.0 0.3 0.8 0.2 0.6 0.1 0.3 0.7 0.3 0.0 0.0 0.4 0.1 0.7 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.8 1.1 0.1 1.2 0.3 0.6 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 P2RY6 P2Y6 ENSG00000171631 "Pyrimidinergic receptor P2Y6" Q15077 11 73264505-73298617 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood: 36.4;lymphoid tissue: 31.1;placenta: 38.0" "Cell line enhanced" "Detected in some" "AN3-CA: 32.9;EFO-21: 10.4;MCF7: 15.3;SK-BR-3: 26.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 10.9;plasmacytoid DC: 36.4" "Lineage enriched" "Detected in many" 20 "dendritic cells: 36.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB022740, HPA074751" Enhanced "CAB022740: , HPA074751: " "unprognostic (2.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.04e-2)" "unprognostic (5.54e-3)" "unprognostic (4.18e-3)" "unprognostic (1.94e-2)" "unprognostic (3.93e-3)" "unprognostic (4.00e-3)" "unprognostic (1.86e-4)" "unprognostic (3.08e-1)" "unprognostic (1.25e-2)" "unprognostic (2.18e-1)" "prognostic unfavourable (2.50e-7)" "unprognostic (1.48e-2)" "unprognostic (1.38e-3)" "unprognostic (7.67e-2)" "unprognostic (1.05e-1)" 2.5 1.8 2.7 8.3 3.5 0.8 1.5 0.5 3.2 2.5 2.1 3.1 0.0 3.0 1.2 2.6 2.9 1.6 2.4 2.7 1.8 1.0 6.2 3.7 3.0 4.8 2.3 1.7 2.1 1.7 0.5 2.7 38.0 2.8 2.1 2.2 5.9 2.0 0.9 2.9 0.9 4.9 3.4 3.8 31.1 1.9 0.8 3.5 3.3 5.0 1.8 3.1 4.1 1.6 0.0 36.4 0.1 1.8 1.5 0.1 1.0 0.7 7.8 0.0 32.9 0.0 0.0 6.8 0.1 0.0 0.1 0.1 7.1 0.1 0.0 10.4 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 3.7 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.1 15.3 0.1 1.3 0.1 0.0 0.0 0.0 0.9 5.4 0.0 0.1 0.5 1.4 26.6 0.0 6.3 1.4 0.1 1.3 0.1 1.0 0.1 0.3 0.0 0.0 1.3 2.1 0.0 0.0 1.1 0.0 0.0 1.8 0.1 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.1 1.5 0.6 36.4 0.0 1.0 2.7 3.5 0.5 3.2 1.8 1.0 2.3 1.7 2.8 3.5 P2RY8 P2Y8 ENSG00000182162 "P2Y receptor family member 8" Q86VZ1 X 1462572-1537107 "Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 26.7;lymphoid tissue: 19.0" "Cell line enhanced" "Detected in some" "Daudi: 33.2;RPMI-8226: 20.4;THP-1: 20.4;U-266/70: 27.9;U-698: 54.3;U-937: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" HPA003631 Enhanced "HPA003631: AB_1079543" "unprognostic (4.32e-2)" "unprognostic (3.22e-5)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "prognostic favourable (7.80e-5)" "prognostic favourable (1.73e-4)" "unprognostic (5.27e-3)" "unprognostic (5.76e-3)" "unprognostic (5.52e-3)" "prognostic favourable (6.54e-4)" "unprognostic (4.29e-2)" "unprognostic (8.45e-3)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.80e-1)" 2.9 4.8 0.5 8.9 2.2 13.9 8.2 0.9 1.8 4.7 1.6 0.5 0.5 1.3 7.1 0.5 0.8 0.8 1.6 11.8 0.9 0.2 13.5 0.8 2.1 19.0 3.6 1.7 5.8 1.1 1.0 6.9 3.4 2.7 1.6 1.3 0.5 1.6 0.5 1.1 0.4 7.8 0.5 3.9 16.6 2.0 0.5 2.0 0.5 8.1 0.5 16.7 2.7 2.8 18.5 5.8 17.8 7.3 15.6 26.7 18.3 0.1 0.1 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 33.2 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.3 0.3 1.6 0.0 14.5 3.5 0.0 0.0 0.0 0.0 0.0 0.3 14.0 0.0 0.0 16.4 16.4 0.2 0.3 14.8 0.1 20.4 0.0 0.2 0.0 0.2 0.1 0.3 0.1 0.1 20.4 0.0 0.3 0.3 0.1 0.0 27.9 5.2 54.3 0.0 16.9 0.0 17.8 7.3 12.4 26.7 5.5 24.6 15.4 20.2 25.1 5.8 18.5 16.1 16.5 4.7 15.6 2.2 1.5 15.9 18.3 0.5 2.2 0.9 1.8 0.9 0.2 3.6 1.7 2.7 2.0 PRLHR "GPR10, PrRPR" ENSG00000119973 "Prolactin releasing hormone receptor" P49683 10 118589989-118595699 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 11.3;brain: 10.6;cervix, uterine: 8.3;pituitary gland: 11.8;smooth muscle: 8.1" "Cell line enriched" "Detected in single" 9 "SH-SY5Y: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA039361 Enhanced "HPA039361: AB_10673527" "unprognostic (1.83e-1)" "unprognostic (2.62e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" 0.2 11.3 1.4 0.2 3.0 0.2 0.1 3.2 5.1 8.3 0.2 0.8 0.0 0.3 5.4 0.2 0.2 0.4 0.2 0.1 0.6 4.0 0.1 0.2 0.2 0.1 3.4 0.9 0.1 0.5 0.1 11.8 0.1 10.6 0.3 0.2 0.1 0.2 1.4 0.2 0.2 0.2 8.1 0.5 0.2 0.5 0.2 1.0 0.0 0.2 0.0 0.1 0.1 5.4 0.5 0.4 1.3 0.3 0.7 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.5 0.3 0.2 0.2 0.1 0.2 0.2 0.1 0.2 0.0 0.5 0.3 0.2 1.3 0.7 0.3 0.4 0.0 0.0 1.4 3.0 3.2 1.9 0.6 4.0 3.4 0.9 10.6 1.0 PROKR1 "GPR73, GPR73a, PKR1, ZAQ" ENSG00000169618 "Prokineticin receptor 1" Q8TCW9 2 68643589-68658247 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.3;epididymis: 8.9" "Cell line enhanced" "Detected in some" "HMC-1: 2.2;NTERA-2: 6.5;SCLC-21H: 1.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "intermediate monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA029396 Uncertain "HPA029396: AB_10610285" "unprognostic (5.46e-2)" "unprognostic (1.60e-2)" "unprognostic (8.75e-2)" "unprognostic (4.99e-4)" "unprognostic (1.18e-1)" "unprognostic (2.55e-3)" "unprognostic (1.07e-1)" "unprognostic (2.91e-2)" "unprognostic (1.85e-1)" "unprognostic (4.52e-2)" "unprognostic (1.89e-1)" "unprognostic (9.72e-2)" "unprognostic (8.96e-7)" "unprognostic (4.07e-2)" "unprognostic (2.53e-1)" "unprognostic (4.19e-1)" "unprognostic (7.22e-2)" 3.3 2.6 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 PROKR2 "dJ680N4.3, GPR73b, GPR73L1, GPRg2, KAL3, PKR2" ENSG00000101292 "Prokineticin receptor 2" Q8NFJ6 20 5302040-5314369 "Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.7;brain: 5.9" "Cell line enhanced" "Detected in some" "HaCaT: 1.6;NTERA-2: 3.2;SCLC-21H: 1.1;SH-SY5Y: 6.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory CD8 T-cell: 1.6;neutrophil: 1.1" "Group enriched" "Detected in many" 8 "granulocytes: 1.1;T-cells: 1.6" "Region enhanced" "Detected in many" "olfactory region: 20.9" "Low region specificity" "Detected in all" HPA047281 Uncertain "HPA047281: AB_10960057" "unprognostic (1.36e-1)" "unprognostic (1.69e-1)" 0.0 0.0 0.4 0.0 0.5 3.7 0.1 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.5 0.4 0.0 0.0 0.0 1.8 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 1.4 0.1 0.0 0.1 0.0 0.3 0.3 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 1.1 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.2 1.1 0.1 0.0 0.0 0.0 0.0 PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "blood: 98.3" "Group enriched" "Detected in some" 4 "HBEC3-KT: 14.3;HMC-1: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "classical monocyte: 28.2;eosinophil: 98.3;neutrophil: 85.7" "Group enriched" "Detected in many" 5 "granulocytes: 98.3;monocytes: 28.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA027543 Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA027543: AB_10610287" "unprognostic (2.22e-2)" "unprognostic (2.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.23e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.38e-2)" 5.6 2.3 2.4 16.2 1.9 20.3 2.4 0.6 2.0 6.9 3.4 1.6 3.5 1.8 2.8 1.4 16.8 2.8 7.5 3.5 2.1 2.3 6.4 1.8 9.2 6.1 4.1 1.0 1.5 2.7 0.9 0.7 3.5 1.8 2.6 3.4 0.6 3.4 2.6 1.1 2.8 5.0 3.8 5.1 15.4 2.3 2.2 1.1 2.3 1.4 22.2 21.7 5.9 3.6 1.5 13.2 98.3 28.2 0.0 0.1 10.1 7.5 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 2.1 0.5 0.0 0.0 5.2 0.2 14.3 0.3 0.1 0.2 2.8 0.0 0.3 0.0 0.7 52.4 0.0 2.3 0.1 0.1 0.0 0.2 0.2 0.0 0.5 0.0 7.1 0.2 0.1 0.1 0.0 0.0 3.5 0.8 0.1 0.0 0.0 7.1 0.0 0.1 2.0 0.0 0.1 0.3 0.0 0.0 0.5 0.4 2.1 0.0 0.9 0.2 5.9 28.2 98.3 0.0 8.9 0.1 1.5 0.0 0.0 13.2 0.7 0.0 0.0 85.7 0.0 3.5 0.1 0.1 10.1 2.4 1.9 0.6 2.0 2.1 2.3 4.1 1.0 1.8 1.1 PTGDR "DP, DP1, PTGDR1" ENSG00000168229 "Prostaglandin D2 receptor" Q13258 14 52267713-52276724 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 30.1" "Group enriched" "Detected in some" 4 "ASC diff: 1.4;HSkMC: 1.5;REH: 2.4;U-138 MG: 1.8" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "pons and medulla: 13.9" "Group enriched" "Detected in many" 5 "gdT-cell: 25.4;MAIT T-cell: 12.7;memory CD8 T-cell: 15.2;naive CD8 T-cell: 8.9;NK-cell: 30.1" "Group enriched" "Detected in many" 30 "NK-cells: 30.1;T-cells: 25.4" "Low region specificity" "Detected in many" HPA049668 Enhanced "HPA049668: " "unprognostic (9.32e-3)" "unprognostic (3.31e-2)" "unprognostic (1.00e-2)" "unprognostic (2.04e-3)" "unprognostic (4.80e-2)" "unprognostic (2.70e-2)" "unprognostic (3.11e-3)" "unprognostic (5.00e-2)" "unprognostic (9.38e-3)" "unprognostic (4.94e-2)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (5.60e-8)" "unprognostic (1.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.02e-2)" "unprognostic (5.89e-2)" 3.9 0.9 0.7 9.6 2.5 1.8 9.3 1.4 1.4 5.5 10.0 0.7 0.9 1.1 4.1 2.2 2.1 2.5 4.9 2.3 0.8 0.8 1.5 1.8 3.4 8.9 1.0 3.5 2.3 0.8 0.8 4.5 0.4 13.9 2.1 12.8 11.2 2.6 3.5 0.9 1.3 2.4 2.0 3.6 10.9 2.0 0.9 0.8 1.8 2.5 0.1 3.1 3.3 3.2 0.0 0.0 0.9 0.1 30.1 25.4 4.1 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 25.4 0.0 12.7 0.0 3.5 15.2 0.0 0.0 0.6 8.9 0.9 30.1 0.1 0.0 0.0 4.1 0.7 2.5 1.4 1.4 0.8 0.8 1.0 3.5 13.9 0.8 PTGDR2 "CD294, CRTH2, DP2, GPR44" ENSG00000183134 "Prostaglandin D2 receptor 2" Q9Y5Y4 11 60850940-60855971 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 51.8;lymphoid tissue: 28.1" "Cell line enhanced" "Detected in some" "HEL: 10.3;Hep G2: 5.0;HMC-1: 6.5;K-562: 4.2;NB-4: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 35.1;eosinophil: 51.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 51.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014259 Uncertain "HPA014259: AB_1849304" "unprognostic (9.77e-2)" "unprognostic (1.35e-3)" "unprognostic (5.45e-3)" "unprognostic (1.69e-1)" "unprognostic (1.90e-1)" "unprognostic (1.85e-3)" "unprognostic (1.70e-1)" "unprognostic (2.30e-4)" "unprognostic (2.61e-1)" "unprognostic (7.92e-2)" "unprognostic (8.68e-3)" "unprognostic (1.52e-1)" "unprognostic (1.32e-2)" "unprognostic (1.52e-1)" "unprognostic (3.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.99e-2)" 1.2 0.3 3.9 2.3 8.0 0.4 2.8 2.3 8.2 1.7 10.7 4.0 0.3 7.5 0.9 0.6 1.4 1.5 1.6 5.1 4.3 2.8 0.5 0.7 1.4 1.9 4.9 5.9 0.5 1.1 5.9 0.6 1.9 5.7 0.9 7.4 0.6 0.5 0.5 11.3 1.0 10.8 0.9 2.2 1.1 13.3 0.5 0.8 28.1 0.4 5.6 0.6 1.1 0.4 0.0 1.2 51.8 7.8 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.4 1.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 10.3 0.0 5.0 1.2 0.0 6.5 2.2 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.1 3.3 14.8 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.1 0.0 51.8 0.0 2.5 0.0 0.0 0.3 0.2 1.2 0.0 0.0 0.0 0.1 0.0 7.8 0.2 0.3 0.4 3.9 8.0 2.3 8.2 4.3 2.8 4.9 5.9 5.7 0.8 PTGER3 EP3 ENSG00000050628 "Prostaglandin E receptor 3" P43115 1 70852353-71047808 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 71.2;endometrium 1: 65.2" "Cell line enhanced" "Detected in some" "ASC diff: 14.9;HAP1: 10.5;HDLM-2: 15.9;HEL: 7.7;T-47d: 36.6" "Group enriched" "Detected in some" 7 "breast cancer: 4.1;renal cancer: 9.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 49 "basophil: 22.4" "Lineage enriched" "Detected in single" 49 "granulocytes: 22.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010689 Uncertain "HPA010689: AB_1855883" "unprognostic (1.53e-3)" "unprognostic (3.48e-1)" "unprognostic (1.11e-1)" "unprognostic (3.86e-3)" "unprognostic (1.47e-1)" "unprognostic (3.37e-2)" "unprognostic (4.80e-2)" "unprognostic (2.01e-2)" "unprognostic (1.24e-1)" "unprognostic (4.64e-3)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "prognostic unfavourable (3.50e-4)" "unprognostic (8.83e-3)" "unprognostic (1.86e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-4)" 32.5 3.0 3.9 6.8 0.7 0.0 71.2 0.2 1.7 7.8 6.3 0.1 3.0 0.5 65.2 16.6 1.7 4.8 11.3 2.6 0.6 2.0 41.5 0.3 0.6 2.2 0.4 1.4 2.4 10.7 0.0 0.4 0.5 1.6 3.3 1.0 0.1 15.5 3.7 0.5 6.2 1.8 31.9 0.5 0.3 9.1 4.0 0.0 0.0 0.7 3.2 0.7 4.4 5.7 0.0 0.4 22.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 14.9 0.3 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.7 0.0 10.5 0.0 0.0 15.9 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.5 0.0 0.1 0.0 36.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 0.0 22.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.7 0.2 1.7 0.6 2.0 0.4 1.4 1.6 0.0 PTGER4 EP4 ENSG00000171522 "Prostaglandin E receptor 4" P35408 5 40679498-40693735 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 57.2" "Cell line enhanced" "Detected in many" "HDLM-2: 18.8;HUVEC TERT2: 13.3;LHCN-M2: 13.0;RT4: 18.9;THP-1: 12.6;TIME: 23.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011226, HPA012756" Approved "HPA011226: AB_1855885, HPA012756: AB_1855884" "unprognostic (1.79e-2)" "unprognostic (6.53e-3)" "unprognostic (9.43e-3)" "unprognostic (6.77e-3)" "unprognostic (1.44e-1)" "unprognostic (7.16e-2)" "unprognostic (7.28e-3)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "unprognostic (3.61e-2)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (1.44e-1)" "prognostic favourable (2.48e-4)" 10.3 5.1 1.4 12.8 1.2 34.7 6.9 0.4 0.8 8.5 24.8 1.7 1.1 9.4 4.8 2.8 6.0 6.1 14.5 9.0 1.1 1.3 8.4 3.7 16.5 16.6 2.2 0.1 4.3 57.2 0.3 1.6 2.3 2.1 7.0 7.9 4.1 3.6 1.0 7.4 4.0 28.7 6.6 4.5 18.2 8.9 2.1 1.2 23.3 3.3 5.7 9.5 11.6 6.2 1.3 5.4 9.3 15.6 2.5 11.4 4.1 1.6 0.3 0.0 0.0 8.1 9.7 0.0 0.1 0.6 0.5 0.3 0.0 0.5 0.2 0.1 0.0 1.2 0.1 3.0 0.8 18.8 0.3 0.0 0.6 0.0 7.3 6.9 1.4 1.0 0.5 4.8 1.9 13.3 0.0 4.5 13.0 0.0 6.9 3.2 0.0 2.8 4.7 1.3 0.6 1.8 18.9 0.0 0.0 0.3 0.6 0.0 2.9 12.6 23.9 2.5 0.0 0.0 0.6 0.0 0.1 0.9 1.1 5.2 0.6 3.5 4.5 9.3 11.4 12.8 6.6 1.3 6.9 7.1 5.4 1.3 4.2 6.1 8.7 2.5 15.6 0.8 5.5 4.1 1.4 1.2 0.4 0.8 1.1 1.3 2.2 0.1 2.1 1.2 PTH1R "PTHR, PTHR1" ENSG00000160801 "Parathyroid hormone 1 receptor" Q03431 3 46877746-46903799 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 90.4" "Cell line enriched" "Detected in some" 7 "RPTEC TERT1: 50.5" "Cancer enhanced" "Detected in many" "renal cancer: 18.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007978 Approved "HPA007978: AB_1854967" "unprognostic (1.26e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-5)" "unprognostic (7.46e-2)" "unprognostic (3.46e-1)" "unprognostic (5.02e-2)" "unprognostic (3.84e-3)" "unprognostic (5.47e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (7.51e-2)" "unprognostic (8.44e-2)" "prognostic favourable (6.79e-6)" "unprognostic (4.22e-3)" "unprognostic (1.50e-1)" "unprognostic (1.35e-4)" "unprognostic (6.62e-3)" 8.5 17.9 4.2 1.4 5.9 0.8 5.0 3.7 5.0 6.2 2.3 5.2 1.1 1.5 4.5 2.5 2.3 3.8 2.8 4.3 5.5 3.9 90.4 13.4 4.1 6.9 6.0 5.0 5.4 1.6 1.0 0.9 10.1 4.7 3.2 1.2 3.4 1.5 3.0 4.0 2.6 1.8 4.6 4.1 9.6 1.5 2.2 5.7 0.0 1.2 0.6 1.0 2.8 5.5 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.8 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 2.3 0.0 50.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.2 5.9 3.7 5.0 5.5 3.9 6.0 5.0 4.7 5.7 PTH2R PTHR2 ENSG00000144407 "Parathyroid hormone 2 receptor" P49190 2 208359714-208854503 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.6;brain: 8.9;salivary gland: 8.2" "Cell line enhanced" "Detected in some" "EFO-21: 11.4;HEL: 16.2;HL-60: 4.0;SH-SY5Y: 6.7" "Cancer enhanced" "Detected in many" "renal cancer: 6.5" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010655 Approved "HPA010655: " "unprognostic (4.76e-3)" "unprognostic (1.39e-3)" "unprognostic (1.64e-1)" "unprognostic (5.78e-2)" "unprognostic (3.77e-1)" "unprognostic (8.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (3.45e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-1)" "unprognostic (1.09e-3)" "unprognostic (2.54e-3)" "unprognostic (6.87e-2)" "unprognostic (1.30e-2)" "unprognostic (1.37e-2)" 2.5 0.9 6.0 0.6 3.5 8.6 2.1 0.2 8.6 0.2 0.2 0.0 0.0 0.0 1.6 4.9 0.2 0.2 0.2 0.2 8.9 4.3 0.5 1.4 0.3 0.3 0.5 4.3 0.1 1.4 0.0 1.0 2.7 0.1 1.2 0.1 0.0 8.2 1.4 0.1 0.3 0.2 1.2 0.4 0.4 0.1 1.7 0.0 0.0 0.2 0.1 0.2 0.2 0.2 1.4 0.6 0.9 1.3 0.0 0.8 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.7 1.3 0.8 1.4 0.0 0.0 0.0 1.0 0.4 0.0 0.9 0.0 0.9 0.6 0.0 0.4 6.0 3.5 0.2 8.6 8.9 4.3 0.5 4.3 0.1 0.0 QRFPR GPR103 ENSG00000186867 "Pyroglutamylated RFamide peptide receptor" Q96P65 4 121329312-121381059 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 6.9;heart muscle: 4.6" "Cell line enhanced" "Detected in some" "HL-60: 5.2;hTERT-HME1: 7.1;RPTEC TERT1: 4.5;SCLC-21H: 2.9;U-2 OS: 7.7;WM-115: 4.3" "Cancer enriched" "Detected in some" 6 "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014300, HPA050236" Approved "HPA014300: AB_1849251, HPA050236: " "unprognostic (1.24e-2)" "unprognostic (2.30e-1)" "unprognostic (1.93e-2)" "unprognostic (3.21e-1)" "unprognostic (2.77e-1)" "unprognostic (3.21e-4)" "unprognostic (2.71e-1)" "unprognostic (5.77e-3)" "unprognostic (5.37e-2)" "unprognostic (6.33e-2)" "unprognostic (2.12e-1)" "prognostic favourable (3.09e-4)" "unprognostic (3.09e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" 1.6 1.2 0.7 0.3 1.9 0.0 0.5 0.1 2.0 0.3 0.2 0.3 0.0 0.0 0.2 1.1 0.8 0.1 1.1 4.6 1.3 6.9 3.2 0.2 0.1 0.0 0.8 0.8 0.4 0.0 1.0 0.8 0.2 4.9 0.6 0.1 3.3 0.0 2.3 0.1 0.0 0.4 0.2 2.6 0.0 1.3 0.7 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.2 0.0 0.1 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 4.5 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.7 0.0 0.0 0.1 1.8 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.9 0.1 2.0 1.3 6.9 0.8 0.8 4.9 0.0 RHO "CSNBAD1, OPN2, RP4" ENSG00000163914 Rhodopsin P08100 3 129528640-129535169 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Congenital stationary night blindness, Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 151 "retina: 415.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cerebellum: 1.6;cerebral cortex: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013440, CAB022486, CAB034887, CAB034888" Enhanced "CAB022486: , CAB034887: AB_785511, CAB034888: AB_785512, HPA013440: " "unprognostic (4.32e-2)" "unprognostic (1.21e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (2.87e-1)" "unprognostic (1.94e-1)" "unprognostic (9.19e-11)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (2.91e-1)" 0.2 0.0 0.0 0.0 0.3 0.0 0.1 1.6 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.5 0.0 0.0 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.2 0.0 0.0 0.1 415.0 0.3 0.2 0.0 1.8 0.0 0.3 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 2.7 0.2 0.2 0.0 0.0 0.0 0.0 RXFP1 "LGR7, RXFPR1" ENSG00000171509 "Relaxin/insulin like family peptide receptor 1" Q9HBX9 4 158315311-158653372 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7;placenta: 12.2" "Group enriched" "Detected in some" 4 "EFO-21: 23.6;HEL: 7.8;RPTEC TERT1: 10.9" "Cancer enriched" "Detected in single" 9 "endometrial cancer: 3.9" "Group enriched" "Detected in many" 6 "basal ganglia: 10.4;cerebral cortex: 18.5;olfactory region: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA027067 Approved "HPA027067: AB_10602127" "unprognostic (3.07e-3)" "unprognostic (3.02e-3)" "unprognostic (1.05e-1)" "unprognostic (2.53e-3)" "unprognostic (2.97e-2)" "unprognostic (4.15e-3)" "unprognostic (6.13e-2)" "unprognostic (6.18e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-6)" "unprognostic (8.21e-2)" "unprognostic (1.34e-1)" "unprognostic (8.33e-4)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.31e-1)" "unprognostic (6.22e-3)" 0.5 6.5 2.1 0.5 10.4 0.2 0.4 0.4 19.7 4.0 0.5 0.0 1.1 0.3 9.0 1.6 0.5 1.3 1.2 0.4 2.0 1.7 2.9 2.1 5.1 0.7 0.8 12.4 0.8 0.6 0.2 0.6 12.2 0.0 1.0 0.3 0.6 0.4 4.2 0.4 0.4 0.9 1.3 0.4 0.6 0.6 0.6 0.0 0.0 2.4 0.0 0.6 0.5 2.2 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.1 10.4 0.4 18.5 2.0 1.7 0.8 12.4 0.0 0.0 RXFP3 "GPCR135, RLN3R1, RXFPR3, SALPR" ENSG00000182631 "Relaxin/insulin like family peptide receptor 3" Q9NSD7 5 33936386-33938237 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 3.1;brain: 1.1;pancreas: 1.7;pituitary gland: 1.1" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA027833 Uncertain "HPA027833: AB_1849247" "unprognostic (1.93e-2)" "unprognostic (3.66e-1)" "unprognostic (2.89e-1)" "unprognostic (2.86e-1)" "unprognostic (9.68e-2)" "unprognostic (1.72e-1)" "unprognostic (8.67e-3)" 0.0 3.1 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 1.7 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236888-101241518 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 88.9" "Cell line enhanced" "Detected in many" "BJ: 19.0;HUVEC TERT2: 53.7;TIME: 29.9;U-251 MG: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles Vesicles "CAB010104: AB_2238920, HPA075568: " "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavourable (8.78e-4)" 72.3 8.4 24.7 16.6 26.2 9.7 46.3 21.6 21.8 13.3 10.5 9.5 2.5 5.7 12.1 5.0 14.7 11.5 17.6 43.5 22.9 15.4 8.9 20.5 35.7 24.5 23.2 14.0 7.9 11.0 13.4 4.7 29.6 21.2 8.9 7.0 9.3 7.5 5.6 21.7 8.2 9.8 19.0 11.0 35.2 8.0 5.8 13.9 4.4 17.0 8.7 15.7 15.2 18.5 27.4 0.2 88.9 0.2 33.4 49.8 30.8 3.5 0.0 3.8 0.0 0.4 9.1 0.0 19.0 3.4 11.5 4.1 0.0 0.1 0.0 4.7 6.6 0.0 0.5 0.2 7.7 1.3 0.3 1.3 0.1 0.0 1.8 0.0 0.8 12.2 0.0 0.0 0.9 53.7 0.0 3.9 3.6 0.0 4.5 0.0 1.0 1.2 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 29.9 1.9 0.7 0.4 36.8 0.3 0.0 0.2 0.1 0.0 0.1 88.9 0.1 4.9 49.8 0.1 40.2 25.1 45.3 44.1 0.2 27.4 35.7 36.2 1.4 33.4 0.2 0.2 26.8 30.8 24.7 26.2 21.6 16.8 22.9 15.4 23.2 14.0 21.2 13.9 S1PR2 "AGR16, DFNB68, EDG5, Gpcr13, H218" ENSG00000267534 "Sphingosine-1-phosphate receptor 2" O95136 19 10221433-10231331 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 14.3;Daudi: 25.2;U-266/70: 18.9;U-698: 27.3;WM-115: 18.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 23.7" "Group enriched" "Detected in many" 7 "granulocytes: 23.7;T-cells: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014255, HPA014307" Approved Uncertain "Nuclear speckles,Golgi apparatus" "Golgi apparatus" "Nuclear speckles" "HPA014255: , HPA014307: AB_1847989" "unprognostic (5.38e-3)" "unprognostic (1.83e-3)" "unprognostic (1.20e-1)" "unprognostic (1.26e-2)" "unprognostic (3.31e-2)" "unprognostic (1.05e-3)" "unprognostic (8.50e-2)" "unprognostic (8.71e-2)" "unprognostic (2.84e-1)" "unprognostic (1.70e-1)" "unprognostic (7.40e-3)" "unprognostic (1.47e-2)" "prognostic unfavourable (4.36e-10)" "unprognostic (4.91e-2)" "unprognostic (4.56e-2)" "unprognostic (3.11e-1)" "unprognostic (8.09e-2)" 17.1 2.3 1.4 13.7 1.3 0.9 7.2 0.9 1.5 13.3 4.1 1.7 3.9 1.8 8.3 9.2 6.4 7.9 6.5 6.1 1.3 1.5 2.4 9.5 11.2 10.6 1.3 0.0 12.9 2.6 3.9 2.2 31.3 1.7 9.8 2.5 3.2 9.4 5.7 3.4 4.0 3.9 8.7 1.7 2.2 4.2 21.8 1.0 2.0 3.3 6.3 15.6 8.0 12.0 0.3 1.6 23.7 1.9 2.1 7.4 1.2 1.4 0.2 1.6 3.3 9.2 11.2 14.3 2.1 4.3 0.9 2.0 0.9 0.8 25.2 2.5 3.9 0.8 0.6 1.0 0.6 2.5 1.3 0.6 0.6 0.6 3.0 0.7 0.5 6.1 0.5 1.8 0.6 0.1 0.6 5.5 0.6 1.1 0.3 1.2 1.7 0.8 1.7 0.7 0.9 0.8 1.2 1.2 2.3 1.2 0.7 1.7 0.6 0.6 0.2 3.5 1.1 7.8 0.6 18.9 8.9 27.3 1.3 1.3 18.7 23.7 1.9 0.4 4.9 1.5 5.9 0.2 6.2 4.6 1.6 0.3 2.6 2.6 0.5 2.1 0.6 0.2 7.4 1.2 1.4 1.3 0.9 1.3 1.3 1.5 1.3 0.0 1.7 1.0 S1PR4 EDG6 ENSG00000125910 "Sphingosine-1-phosphate receptor 4" O95977 19 3172346-3180332 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 44.2;bone marrow: 14.9;lymphoid tissue: 35.9" "Cell line enhanced" "Detected in some" "HDLM-2: 10.8;HL-60: 14.4;NB-4: 14.2;REH: 40.1;U-937: 13.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA060601, HPA067232" Supported Mitochondria Mitochondria "HPA060601: , HPA067232: " "prognostic favourable (3.13e-4)" "prognostic favourable (1.33e-4)" "unprognostic (2.58e-2)" "prognostic favourable (2.22e-4)" "unprognostic (2.98e-2)" "prognostic favourable (1.45e-6)" "unprognostic (1.27e-2)" "unprognostic (8.73e-2)" "unprognostic (1.21e-3)" "unprognostic (6.64e-3)" "unprognostic (3.59e-1)" "unprognostic (2.20e-1)" "prognostic unfavourable (2.87e-4)" "unprognostic (2.97e-1)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (6.15e-3)" 2.0 0.5 0.7 8.3 0.3 14.9 1.3 0.6 0.7 0.5 0.9 0.4 0.2 0.8 0.7 0.7 1.2 1.4 0.7 2.1 0.3 0.2 1.2 1.4 6.4 35.9 0.3 0.4 0.7 0.3 0.0 0.2 1.7 0.6 0.7 0.0 1.0 1.3 0.2 1.1 0.4 7.1 0.2 0.5 34.2 3.9 0.3 0.3 10.2 1.5 0.2 10.7 1.9 0.6 14.1 7.3 44.2 15.3 5.4 23.1 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.9 0.1 0.0 0.1 0.0 0.0 0.0 10.8 0.0 4.6 0.1 0.0 0.0 14.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 40.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 13.7 0.0 16.4 10.4 27.4 11.8 11.6 10.5 11.3 14.7 11.4 7.3 14.1 12.4 11.9 44.2 5.4 15.3 6.6 23.1 7.2 0.7 0.3 0.6 0.7 0.3 0.2 0.3 0.4 0.6 0.3 S1PR5 "Edg-8, EDG8" ENSG00000180739 "Sphingosine-1-phosphate receptor 5" Q9H228 19 10512742-10517931 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 62.0;brain: 37.8;skin 1: 25.4" "Cell line enhanced" "Detected in some" "HaCaT: 21.5;HBEC3-KT: 8.3;RT4: 14.0;T-47d: 8.9;U-2 OS: 8.0" "Group enriched" "Detected in many" 5 "cervical cancer: 11.7;head and neck cancer: 8.0;lung cancer: 3.7;urothelial cancer: 6.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 62.0;MAIT T-cell: 38.0;memory CD8 T-cell: 29.2;naive CD8 T-cell: 23.2" "Lineage enriched" "Detected in many" 8 "T-cells: 62.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029683 Enhanced "HPA029683: AB_10603237" "unprognostic (9.07e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (5.55e-4)" "unprognostic (4.21e-1)" "unprognostic (4.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.55e-1)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (6.71e-7)" "unprognostic (2.46e-2)" "unprognostic (2.90e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-1)" 1.4 1.0 10.0 1.6 17.4 21.0 1.1 1.9 15.1 2.7 1.0 37.8 0.0 0.9 1.1 6.9 6.5 1.0 1.0 0.9 15.7 8.0 1.1 2.7 3.0 1.7 28.8 9.3 0.7 0.8 0.6 0.2 2.8 13.9 2.0 0.8 0.7 1.3 1.4 1.4 25.4 1.0 0.9 26.2 11.6 0.9 0.9 21.0 0.0 0.8 0.2 3.3 3.1 5.0 0.1 0.1 0.8 0.1 8.1 62.0 10.2 1.4 2.2 0.4 0.0 0.0 0.1 0.1 0.5 0.3 0.6 0.4 0.2 0.1 0.0 5.9 0.2 21.5 1.4 8.3 1.6 0.0 1.4 0.2 1.7 0.0 0.0 0.0 0.1 0.0 3.9 2.3 0.4 0.0 0.1 0.0 0.0 2.7 0.8 0.0 3.4 0.4 0.0 1.6 0.0 0.0 14.0 0.0 0.0 3.5 0.0 0.4 8.9 2.5 0.0 1.1 8.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.2 62.0 0.0 38.0 0.1 7.8 29.2 0.1 0.1 2.4 23.2 0.8 8.1 0.1 0.1 0.1 10.2 10.0 17.4 1.9 15.1 15.7 8.0 28.8 9.3 13.9 21.0 SCTR ENSG00000080293 "Secretin receptor" P47872 2 119439843-119525301 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 13.5;pancreas: 35.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.3" "Cell type enhanced" "Detected in some" "basophil: 3.8" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 12 "midbrain: 1.2;pons and medulla: 1.3;thalamus: 1.5" HPA007269 Uncertain "HPA007269: AB_1856640" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (4.99e-2)" "unprognostic (5.82e-2)" "unprognostic (1.71e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (9.08e-2)" "unprognostic (7.35e-2)" "unprognostic (2.38e-2)" "unprognostic (6.11e-3)" "unprognostic (1.65e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-1)" "unprognostic (4.38e-2)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.2 4.1 0.0 0.0 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.9 0.2 0.2 0.0 0.0 0.0 0.5 0.1 3.8 0.3 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.8 0.0 0.5 0.1 0.0 0.0 0.0 0.6 0.0 0.0 8.0 0.7 0.5 0.1 0.0 0.8 0.0 0.1 0.0 1.4 0.3 0.5 0.0 0.3 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.3 0.6 0.0 0.9 0.3 0.1 0.0 0.0 0.1 3.8 0.3 0.9 0.3 0.2 0.4 0.3 0.3 0.0 0.0 0.5 0.3 0.2 1.2 0.3 0.3 0.1 0.4 0.0 SMO "FZD11, SMOH" ENSG00000128602 "Smoothened, frizzled class receptor" Q99835 7 129188872-129213545 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 20.0;AN3-CA: 37.1;NTERA-2: 28.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011446 Approved "CAB011446: " "unprognostic (2.48e-2)" "unprognostic (2.69e-2)" "unprognostic (7.09e-2)" "unprognostic (1.10e-1)" "unprognostic (8.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.38e-3)" "unprognostic (1.59e-1)" "unprognostic (1.17e-2)" "unprognostic (8.74e-3)" "unprognostic (1.62e-1)" "unprognostic (5.15e-3)" "unprognostic (2.09e-1)" "unprognostic (2.25e-1)" "unprognostic (2.61e-2)" 4.0 4.1 4.2 3.8 4.8 0.5 7.4 5.3 4.6 18.2 5.8 5.1 9.2 2.5 20.9 18.7 10.3 11.4 10.0 5.2 8.4 3.7 10.6 13.7 2.4 2.0 4.3 4.5 23.0 7.1 14.4 13.5 2.6 9.0 18.4 2.2 17.2 9.4 12.8 3.5 16.6 3.5 9.8 7.0 2.0 4.2 7.9 3.4 5.3 9.2 6.8 4.6 6.3 17.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 7.8 20.0 37.1 0.5 0.1 6.3 2.2 2.9 4.4 2.6 6.0 0.1 0.0 6.1 4.4 12.2 12.0 0.6 1.7 0.0 9.8 3.9 0.0 9.6 2.5 0.1 0.0 7.3 4.9 1.4 0.0 2.5 0.6 0.0 1.3 0.0 10.2 0.0 28.4 2.2 14.8 8.5 0.0 2.3 0.0 0.6 13.4 0.0 0.0 5.2 4.9 2.5 0.0 0.3 6.4 7.7 4.2 0.4 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.8 5.3 4.6 8.4 3.7 4.3 4.5 9.0 3.4 SSTR1 ENSG00000139874 "Somatostatin receptor 1" P30872 14 38207999-38213067 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.0;intestine: 14.3;stomach 1: 22.8" "Cell line enhanced" "Detected in some" "BJ: 46.8;BJ hTERT+: 13.0;BJ hTERT+ SV40 Large T+: 8.6;fHDF/TERT166: 27.6;HeLa: 10.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003207, HPA031506" Approved Supported "Plasma membrane" "Plasma membrane" "HPA003207: , HPA031506: " "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-1)" "unprognostic (2.50e-3)" "unprognostic (4.34e-2)" "unprognostic (9.90e-2)" "unprognostic (3.66e-3)" "unprognostic (1.91e-1)" "unprognostic (6.16e-3)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (9.19e-2)" "prognostic favourable (4.28e-4)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" "unprognostic (3.28e-2)" 0.7 0.4 6.8 0.6 6.9 0.0 0.6 0.5 15.0 0.9 3.7 0.6 0.1 14.3 1.0 0.6 0.4 0.7 0.5 0.8 4.3 10.4 2.2 6.7 5.5 0.1 6.8 4.0 0.6 3.8 0.1 1.4 2.8 2.8 1.2 2.5 0.2 0.2 0.5 0.7 0.4 8.2 0.6 1.3 0.7 22.8 0.1 0.7 0.1 0.3 0.1 0.1 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 46.8 13.0 8.6 0.7 0.4 0.0 0.0 0.0 27.6 0.1 0.0 0.0 6.3 0.0 0.0 0.0 10.6 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 1.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 6.9 0.5 15.0 4.3 10.4 6.8 4.0 2.8 0.7 SSTR2 ENSG00000180616 "Somatostatin receptor 2" P30874 17 73165012-73176633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.6" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 16.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007264 Uncertain Supported Cytosol Cytosol "HPA007264: AB_1080053" "unprognostic (2.13e-3)" "unprognostic (2.61e-3)" "unprognostic (7.43e-2)" "unprognostic (9.37e-3)" "unprognostic (6.25e-2)" "unprognostic (1.52e-1)" "unprognostic (2.29e-3)" "unprognostic (7.46e-2)" "unprognostic (2.96e-1)" "unprognostic (6.55e-2)" "prognostic favourable (6.63e-4)" "unprognostic (1.07e-1)" "prognostic unfavourable (9.04e-7)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (3.71e-3)" "unprognostic (2.95e-2)" 4.5 7.4 6.1 2.3 15.8 2.5 4.2 23.1 26.6 1.4 2.2 0.5 0.6 3.3 1.9 4.1 1.5 2.3 1.8 2.2 9.3 5.3 13.6 3.3 1.4 2.7 2.6 13.1 1.5 2.0 1.4 5.7 1.0 4.9 2.8 2.7 1.1 1.8 3.6 1.7 1.9 2.5 2.2 3.3 8.3 7.2 1.4 1.9 0.3 2.3 0.0 2.9 2.0 1.9 1.4 1.0 4.7 0.9 0.9 1.0 0.3 0.3 0.5 0.6 1.1 0.2 0.2 0.7 0.2 0.3 0.5 0.5 0.5 0.5 0.7 0.3 0.1 0.5 0.1 0.1 0.2 0.6 0.9 0.6 1.0 0.5 0.1 0.4 2.2 0.2 0.1 0.2 0.0 0.0 0.7 1.2 0.2 0.6 0.4 1.3 1.5 0.6 0.7 0.8 0.4 0.4 0.6 16.8 1.4 0.3 0.3 0.2 2.1 0.3 0.3 0.4 2.2 0.6 0.3 0.8 0.4 1.6 0.3 1.7 0.4 3.8 0.9 1.2 1.0 0.7 0.8 0.8 0.8 0.8 0.3 1.4 0.8 0.9 4.7 0.9 0.8 1.0 0.5 0.3 6.1 15.8 23.1 22.1 9.3 5.3 2.6 13.1 4.9 1.9 SSTR3 ENSG00000278195 "Somatostatin receptor 3" P32745 22 37204238-37212322 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.1;lymphoid tissue: 29.6;testis: 11.3" "Group enriched" "Detected in some" 11 "RPMI-8226: 21.8;SCLC-21H: 8.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.9" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 3.9;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 10 "T-cells: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022647 Approved "CAB022647: " "unprognostic (1.63e-2)" "unprognostic (5.58e-3)" "unprognostic (1.32e-2)" "unprognostic (3.18e-2)" "unprognostic (7.03e-2)" "unprognostic (6.26e-5)" "unprognostic (1.11e-1)" "unprognostic (1.72e-2)" "unprognostic (1.90e-2)" "unprognostic (8.95e-2)" "unprognostic (3.88e-3)" "unprognostic (2.93e-1)" "unprognostic (1.51e-7)" "unprognostic (1.55e-1)" "unprognostic (1.24e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-2)" 0.1 0.8 2.8 1.9 1.9 0.9 0.1 2.7 11.1 0.0 0.5 0.2 0.0 2.6 1.9 0.2 0.1 0.1 0.1 0.0 5.6 0.1 0.0 0.1 3.5 0.0 7.9 5.8 3.9 0.0 6.4 0.0 7.9 0.2 0.6 0.0 0.6 0.1 0.0 0.0 1.0 2.2 4.3 1.2 0.5 11.3 0.1 29.6 0.0 0.0 2.0 0.3 0.0 0.3 0.1 0.1 0.0 0.0 3.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 8.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.3 3.9 3.0 0.1 0.0 0.0 0.1 0.3 0.8 SSTR4 ENSG00000132671 "Somatostatin receptor 4" P31391 20 23035386-23036812 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "brain: 3.8" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA064252 Uncertain "HPA064252: " 0.0 0.0 1.7 0.0 1.1 0.0 0.0 3.0 3.8 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSTR5 ENSG00000162009 "Somatostatin receptor 5" P35346 16 1078781-1080142 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 8.2;lymphoid tissue: 5.2;pituitary gland: 9.0" "Group enriched" "Detected in some" 15 "Hep G2: 9.2;PC-3: 34.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 4.2;hypothalamus: 2.7" "Low region specificity" "Detected in many" HPA066503 Supported "Plasma membrane" "Plasma membrane" "HPA066503: " "unprognostic (2.16e-2)" "unprognostic (7.31e-2)" "unprognostic (3.69e-2)" "unprognostic (2.39e-2)" "unprognostic (2.14e-1)" "unprognostic (9.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.72e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (4.09e-2)" 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.4 0.4 0.0 0.7 0.6 0.9 0.5 0.0 8.2 2.9 0.0 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.0 0.0 0.0 1.1 0.0 0.0 1.1 0.9 0.1 0.1 0.8 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 5.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 1.3 0.3 0.0 1.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 SUCNR1 GPR91 ENSG00000198829 "Succinate receptor 1" Q9BXA5 3 151873643-151884619 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 63.1;lymphoid tissue: 23.3" "Group enriched" "Detected in some" 5 "HEL: 27.4;NB-4: 15.8;U-937: 27.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "eosinophil: 2.0;intermediate monocyte: 1.0;non-classical monocyte: 1.7;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 20 "dendritic cells: 2.2;granulocytes: 2.0;monocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB022745 Uncertain "CAB022745: " "unprognostic (1.54e-1)" "unprognostic (2.65e-2)" "unprognostic (3.45e-2)" "unprognostic (6.94e-2)" "unprognostic (1.58e-1)" "unprognostic (6.01e-2)" "unprognostic (3.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.04e-1)" "unprognostic (8.92e-2)" "unprognostic (2.59e-1)" "unprognostic (1.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.14e-2)" "unprognostic (7.49e-2)" "unprognostic (1.58e-1)" 13.7 1.6 0.6 0.7 0.9 4.7 1.6 0.2 1.2 0.3 0.5 0.7 0.0 0.7 0.4 0.6 0.5 0.3 0.2 2.8 0.4 0.4 63.1 3.6 2.2 3.3 0.6 0.1 0.7 0.4 4.2 0.3 0.2 0.8 0.5 0.5 0.1 1.3 0.0 0.3 0.7 0.5 0.3 0.5 23.3 6.7 0.4 0.0 1.3 14.6 0.8 0.3 0.7 0.3 0.0 2.2 2.0 1.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 4.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.1 2.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 1.7 2.2 0.0 0.2 0.6 0.9 0.2 1.2 0.4 0.4 0.6 0.1 0.8 0.0 TAAR1 "TA1, TAR1, TRAR1" ENSG00000146399 "Trace amine associated receptor 1" Q96RJ0 6 132644984-132646003 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "stomach 1: 13.6" "Cell line enhanced" "Detected in some" "EFO-21: 1.7;HBF TERT88: 1.1" "Cancer enhanced" "Detected in single" "cervical cancer: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055614 Approved "HPA055614: " "unprognostic (2.19e-2)" "unprognostic (1.87e-1)" "unprognostic (1.47e-1)" "unprognostic (2.68e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 2.3 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 13.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAAR5 PNR ENSG00000135569 "Trace amine associated receptor 5" O14804 6 132588673-132589686 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051703 Uncertain "HPA051703: " 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199700 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9" "Cell line enhanced" "Detected in some" "BJ: 1.3;EFO-21: 3.1;fHDF/TERT166: 2.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 40 "basophil: 4.4" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced "HPA074573: " "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" 23.9 1.0 2.0 1.8 8.5 0.3 8.2 0.3 4.8 15.2 1.9 0.1 1.5 0.8 17.7 3.6 4.8 6.9 2.5 0.9 1.5 2.5 1.5 0.4 2.1 2.9 0.9 1.0 4.2 0.7 1.3 1.1 1.6 2.3 6.1 1.4 0.3 2.6 2.5 2.6 8.7 1.4 6.5 0.9 0.4 1.2 2.0 1.5 0.2 1.1 4.3 3.4 4.8 14.3 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 1.1 0.0 0.5 3.1 2.7 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.3 0.6 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 1.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.5 0.1 0.0 0.0 1.2 0.1 0.1 4.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 8.5 0.3 3.6 1.5 2.5 0.9 1.0 2.3 1.5 TACR2 "NK2R, NKNAR, SKR, TAC2R" ENSG00000075073 "Tachykinin receptor 2" P21452 10 69403903-69416867 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.3;smooth muscle: 35.5" "Cell line enhanced" "Detected in some" "SK-MEL-30: 8.5;U-87 MG: 4.9" "Cancer enhanced" "Detected in many" "stomach cancer: 6.7" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "intermediate monocyte: 4.2" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076573 Approved "Plasma membrane" "Plasma membrane" "HPA076573: " "unprognostic (2.83e-1)" "unprognostic (1.58e-3)" "unprognostic (2.48e-2)" "unprognostic (1.67e-1)" "unprognostic (4.22e-1)" "unprognostic (2.30e-1)" "unprognostic (1.30e-2)" "unprognostic (1.96e-2)" "unprognostic (3.72e-1)" "unprognostic (6.14e-2)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (9.88e-4)" "unprognostic (5.59e-3)" "unprognostic (4.31e-3)" "unprognostic (1.25e-3)" "unprognostic (1.32e-1)" 1.6 0.1 0.5 3.1 0.5 0.1 1.2 0.5 1.1 11.1 56.3 0.2 0.4 4.1 12.3 0.9 19.6 7.2 1.2 1.9 0.5 0.3 0.2 0.5 0.8 0.5 0.2 0.4 2.0 0.8 0.0 0.1 0.1 0.4 14.9 8.2 0.2 0.4 0.9 1.1 0.4 14.2 35.5 0.8 0.5 16.5 0.9 0.5 0.1 0.4 0.8 0.4 19.4 3.1 1.2 2.0 0.5 4.2 0.1 0.8 0.3 1.9 1.2 0.4 0.6 3.0 0.2 0.2 0.5 0.3 0.5 0.7 0.7 0.3 0.2 0.5 0.5 0.7 0.1 0.1 0.0 0.4 0.5 1.6 0.6 1.9 0.3 0.0 3.0 0.5 0.7 0.0 0.0 0.2 0.4 2.5 0.0 0.8 0.1 0.5 0.4 1.9 0.1 0.0 0.0 0.0 1.0 0.8 0.6 1.3 2.6 8.5 1.1 0.2 0.8 3.0 0.4 1.2 1.0 1.2 1.3 0.2 4.9 0.3 1.7 0.5 1.5 0.1 0.3 4.2 0.4 1.2 0.8 0.3 2.0 0.6 0.4 0.2 0.2 0.1 1.7 0.3 0.1 0.3 0.5 0.5 0.5 1.1 0.5 0.3 0.2 0.4 0.4 0.5 TACR3 NK3R ENSG00000169836 "Tachykinin receptor 3" P29371 4 103586031-103719816 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.4;urinary bladder: 5.5" "Cell line enriched" "Detected in single" 13 "BEWO: 12.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 14.4;hypothalamus: 4.1;pons and medulla: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA009418 Uncertain "HPA009418: AB_1857727" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (2.29e-1)" "unprognostic (3.50e-1)" "unprognostic (3.21e-1)" "unprognostic (5.52e-1)" "unprognostic (3.80e-1)" "unprognostic (3.42e-2)" "unprognostic (1.72e-2)" 0.1 0.1 14.4 0.1 1.4 0.1 0.4 0.0 2.6 0.1 0.4 0.0 0.0 0.1 0.2 0.4 0.2 0.3 0.3 0.1 1.1 4.1 2.0 0.1 0.9 0.1 1.4 1.0 0.1 0.1 0.1 0.1 0.6 6.3 0.2 0.5 3.2 0.1 0.1 0.7 0.3 0.1 0.1 2.5 0.1 0.5 0.6 0.0 0.0 0.5 0.9 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 1.4 0.0 1.5 1.1 4.1 1.4 1.0 6.3 0.0 TAS1R1 "GPR70, T1R1, TR1" ENSG00000173662 "Taste 1 receptor member 1" Q7RTX1 1 6555181-6579757 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "salivary gland: 10.9;testis: 8.7" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 2.7;HDLM-2: 4.6;Hep G2: 4.5;LHCN-M2: 3.6;U-698: 2.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 15 "neutrophil: 1.4" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA034579, HPA034580" Approved "HPA034579: , HPA034580: AB_10671504" "unprognostic (2.03e-2)" "unprognostic (9.29e-3)" "unprognostic (5.60e-4)" "unprognostic (1.12e-1)" "unprognostic (1.11e-1)" "unprognostic (4.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.53e-4)" "unprognostic (3.89e-2)" "unprognostic (3.15e-1)" "unprognostic (3.26e-2)" "unprognostic (3.17e-1)" "unprognostic (5.45e-3)" "unprognostic (1.67e-1)" "unprognostic (8.26e-2)" "unprognostic (8.28e-2)" "unprognostic (6.22e-2)" 0.4 0.8 0.7 0.1 0.8 1.5 0.4 0.6 1.2 0.7 0.9 0.1 0.1 0.4 0.1 0.1 0.4 0.4 1.0 0.1 1.2 0.2 0.1 0.1 0.6 0.2 0.2 0.1 0.9 0.1 0.0 0.5 0.3 0.5 0.1 0.0 0.7 10.9 2.1 0.6 1.4 0.5 0.1 0.1 1.3 0.5 8.7 0.1 0.1 0.1 2.2 0.5 0.4 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.5 0.1 0.3 0.1 2.7 0.0 0.3 0.0 0.0 4.6 0.0 0.0 0.1 4.5 0.1 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.7 0.8 0.6 1.2 1.2 0.2 0.2 0.1 0.5 0.1 TAS1R3 T1R3 ENSG00000169962 "Taste 1 receptor member 3" Q7RTX0 1 1331314-1335306 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 35.2;salivary gland: 17.9" "Cell line enhanced" "Detected in some" "Karpas-707: 5.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "cerebellum: 1.9" "Cell type enriched" "Detected in single" 37 "memory B-cell: 5.2" "Lineage enriched" "Detected in single" 37 "B-cells: 5.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA053439 Uncertain "HPA053439: " "unprognostic (1.35e-2)" "unprognostic (1.45e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-3)" "unprognostic (4.32e-2)" "unprognostic (2.05e-1)" "unprognostic (6.95e-2)" "unprognostic (4.22e-1)" "unprognostic (8.44e-3)" "unprognostic (7.59e-3)" "unprognostic (8.37e-2)" "unprognostic (1.18e-1)" "unprognostic (2.35e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-1)" 0.4 0.4 0.4 1.5 0.4 0.5 0.4 1.9 0.4 0.6 1.4 0.4 1.0 2.0 0.5 35.2 1.9 0.6 0.7 1.4 0.4 0.1 0.5 1.6 0.9 1.6 0.4 0.4 0.4 0.4 0.1 2.6 1.9 0.4 0.4 0.1 0.4 17.9 0.4 1.4 0.2 3.2 0.4 0.4 6.4 0.9 1.6 0.4 0.4 0.8 1.5 2.5 1.0 0.9 5.2 0.1 0.0 0.0 0.0 0.1 0.2 1.4 1.3 0.3 0.5 0.0 0.0 0.7 0.7 0.2 0.2 0.1 0.9 2.9 1.7 0.3 0.0 0.6 0.0 0.0 0.0 3.6 1.0 0.2 2.5 0.9 0.3 0.0 0.5 0.1 0.2 0.1 0.0 0.0 0.4 5.9 0.0 0.8 0.3 0.6 0.8 3.4 0.9 0.7 0.8 0.0 0.2 2.2 0.4 0.4 2.3 1.9 2.0 0.4 0.3 0.5 0.2 1.8 0.8 3.7 3.4 0.8 0.2 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.4 1.9 0.4 0.4 0.1 0.4 0.4 0.4 0.4 TAS2R1 "T2R1, TRB7" ENSG00000169777 "Taste 2 receptor member 1" Q9NYW7 5 9628997-9712378 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 13.0" "Group enriched" "Detected in some" 5 "BJ hTERT+: 3.5;U-266/84: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051879 Uncertain "HPA051879: " "unprognostic (2.19e-1)" 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAS2R38 "PTC, T2R61" ENSG00000257138 "Taste 2 receptor member 38" P59533 7 141972631-141973773 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "intestine: 2.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.3;NB-4: 1.1;SK-BR-3: 1.1;U-266/70: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA043862, HPA054366" Uncertain "HPA043862: , HPA054366: " "unprognostic (5.18e-3)" "unprognostic (6.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.58e-1)" "unprognostic (1.25e-1)" "unprognostic (8.36e-2)" "unprognostic (5.86e-2)" "unprognostic (8.05e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.9 0.1 0.0 0.0 0.0 2.2 0.2 0.0 0.2 0.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.5 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAS2R39 ENSG00000236398 "Taste 2 receptor member 39" P59534 7 143183419-143184435 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA053456, HPA060680" Uncertain "HPA053456: , HPA060680: " 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAS2R41 T2R59 ENSG00000221855 "Taste 2 receptor member 41" P59536 7 143477873-143478796 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057063 Uncertain "HPA057063: " 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAS2R42 "hT2R55, T2R24, T2R55, TAS2R55" ENSG00000186136 "Taste 2 receptor member 42" Q7RTR8 12 11185993-11186937 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA036149 Uncertain Approved "Nucleoplasm,Actin filaments,Focal adhesion sites" "Nucleoplasm, Actin filaments" "Focal adhesion sites" "HPA036149: AB_10672080" "unprognostic (2.45e-2)" "unprognostic (4.17e-2)" 0.0 0.7 0.2 0.2 0.4 0.0 0.0 1.0 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.6 0.0 0.7 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.4 0.2 0.4 0.1 0.0 0.0 0.0 0.7 0.4 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.7 0.1 0.6 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 TAS2R5 T2R5 ENSG00000127366 "Taste 2 receptor member 5" Q9NYW4 7 141790217-141791367 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 8.8" "Cell line enhanced" "Detected in many" "hTCEpi: 10.4" "Low cancer specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA053742 Approved "Nucleoplasm,Nucleoli,Cytoplasmic bodies" "Nucleoplasm, Nucleoli" "Cytoplasmic bodies" "HPA053742: " "unprognostic (5.48e-3)" "unprognostic (3.90e-3)" "unprognostic (6.07e-2)" "unprognostic (8.00e-3)" "unprognostic (7.56e-2)" "unprognostic (4.87e-2)" "unprognostic (1.90e-1)" "unprognostic (1.71e-1)" "unprognostic (2.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.13e-5)" "unprognostic (1.13e-2)" "unprognostic (8.29e-7)" "unprognostic (1.29e-1)" "unprognostic (3.28e-1)" "unprognostic (6.92e-2)" "unprognostic (1.39e-2)" 1.0 1.0 0.4 1.4 1.1 0.2 3.2 4.9 0.7 2.5 0.9 0.8 2.8 6.1 1.1 3.0 0.8 0.8 0.6 0.7 1.0 0.5 1.1 1.2 0.4 4.6 1.5 0.1 2.9 1.0 1.7 1.2 1.6 1.0 2.6 8.8 1.7 1.2 1.2 1.9 0.7 1.4 1.7 1.2 1.3 2.4 1.0 0.6 0.5 0.2 0.4 1.4 0.1 0.5 0.2 1.4 0.6 0.9 2.7 1.7 0.6 0.6 0.5 0.9 2.0 0.4 1.1 0.9 0.2 0.3 1.5 0.8 0.3 0.6 1.7 0.3 1.2 2.7 0.9 1.7 1.3 2.3 10.4 1.2 2.8 1.0 2.6 0.3 0.1 1.7 0.6 3.9 1.3 0.3 0.2 0.1 2.8 0.4 0.7 2.0 1.2 0.3 0.4 0.2 0.1 0.4 0.3 0.9 0.6 0.6 1.2 1.9 0.4 1.4 0.8 0.8 0.5 0.5 0.2 0.0 1.0 0.0 0.0 0.9 0.3 0.4 0.0 1.0 0.9 1.4 0.0 0.4 0.0 0.6 1.3 0.1 TAS2R60 T2R60 ENSG00000185899 "Taste 2 receptor member 60" P59551 7 143443453-143444409 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 1.3;liver: 1.4;pancreas: 1.3" "Cell line enhanced" "Detected in some" "NTERA-2: 2.3;U-937: 1.4" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA030416 Uncertain "HPA030416: AB_10603344" "unprognostic (1.78e-2)" "unprognostic (7.98e-2)" 0.1 0.0 0.0 0.4 0.0 0.9 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.2 0.0 0.0 1.3 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.5 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 1.0 0.9 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 1.3 0.5 1.0 0.0 0.9 0.0 0.0 0.3 TBXA2R ENSG00000006638 "Thromboxane A2 receptor" P21731 19 3594506-3606840 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 11.7;U-2197: 8.4;U-937: 7.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "naive B-cell: 12.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA077366 Supported "Nuclear speckles,Plasma membrane" "Plasma membrane" "Nuclear speckles" "HPA077366: " "unprognostic (1.59e-1)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (1.74e-1)" "unprognostic (8.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.52e-2)" "unprognostic (2.17e-3)" "unprognostic (8.41e-2)" "unprognostic (6.25e-2)" "prognostic favourable (7.17e-4)" "unprognostic (3.89e-2)" "prognostic unfavourable (1.45e-4)" "unprognostic (4.32e-2)" "unprognostic (9.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.02e-1)" 8.7 11.8 1.4 3.9 1.6 2.1 3.9 0.5 1.6 13.5 3.8 1.7 3.9 2.6 7.4 4.8 8.0 4.7 6.0 6.8 2.4 1.5 10.1 18.4 6.7 7.3 1.4 1.9 8.3 2.2 2.5 1.7 10.6 2.7 3.6 1.4 5.0 1.7 4.2 3.1 1.8 4.4 6.5 2.1 14.9 3.7 3.4 1.9 2.2 3.9 3.2 1.8 6.8 9.6 12.6 0.3 3.2 0.4 3.1 9.6 3.9 0.1 0.2 0.2 4.1 0.9 2.2 0.7 2.9 0.7 2.3 1.8 0.1 0.3 0.1 4.3 1.2 0.1 0.8 0.0 0.8 0.2 1.0 2.8 11.7 0.3 1.2 0.0 5.2 1.1 0.0 3.0 0.0 0.9 4.4 0.4 0.4 0.2 0.2 1.5 0.1 2.5 0.1 0.0 0.2 0.0 0.1 0.2 1.7 0.2 0.4 0.1 1.8 5.0 2.5 4.7 1.0 8.4 2.8 0.2 0.3 0.2 3.9 7.2 1.1 2.9 0.4 0.2 2.6 0.2 0.3 1.8 0.8 2.3 0.0 12.6 4.6 9.6 3.2 3.1 0.2 0.3 0.2 3.9 1.4 1.6 0.5 1.6 2.4 1.5 1.4 1.9 2.7 1.9 TRHR ENSG00000174417 "Thyrotropin releasing hormone receptor" P34981 8 109086621-109119584 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 1.0;pituitary gland: 3.3;thyroid gland: 1.6" "Cell line enhanced" "Detected in some" "PC-3: 1.6;SH-SY5Y: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055162 Approved "HPA055162: " "unprognostic (1.92e-2)" "unprognostic (8.58e-2)" "unprognostic (1.17e-1)" 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 1.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.2 0.3 0.5 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSHR LGR3 ENSG00000165409 "Thyroid stimulating hormone receptor" P16473 14 80954989-81146302 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Congenital hypothyroidism, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "thyroid gland: 158.0" "Group enriched" "Detected in some" 17 "MOLT-4: 18.1;SCLC-21H: 18.7;U-266/70: 9.2;U-266/84: 4.7" "Cancer enriched" "Detected in some" 116 "thyroid cancer: 100.4" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "T-reg: 9.9" "Lineage enriched" "Detected in many" 5 "T-cells: 9.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB000473 Approved "Intracellular and membrane" "CAB000473: AB_2303782" "unprognostic (3.36e-3)" "unprognostic (1.31e-3)" "unprognostic (1.02e-2)" "unprognostic (4.17e-6)" "unprognostic (3.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.83e-1)" "unprognostic (2.66e-2)" "unprognostic (3.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" "unprognostic (7.11e-3)" "unprognostic (5.08e-7)" "unprognostic (1.32e-1)" "unprognostic (7.40e-2)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" 0.1 0.2 0.1 0.2 0.4 0.3 0.2 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.3 0.3 0.5 0.1 0.0 0.8 0.2 0.0 0.1 0.3 0.1 0.0 0.2 0.2 0.1 0.1 0.1 27.3 158.0 0.2 0.4 0.1 0.1 1.8 0.8 1.3 0.3 0.1 9.9 0.1 0.3 0.2 0.6 0.4 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.3 0.4 0.6 0.2 0.1 0.2 0.7 0.0 0.1 0.2 0.1 0.3 0.6 0.3 0.0 0.2 0.3 0.3 0.1 0.1 0.2 0.1 0.3 0.6 0.1 0.4 18.1 0.4 0.4 0.2 0.6 0.2 0.7 0.0 0.4 18.7 0.3 0.1 0.2 0.2 0.3 0.0 0.2 0.5 0.4 0.5 0.2 9.2 4.7 0.4 0.2 0.2 0.3 0.6 0.2 0.2 0.2 0.1 0.2 1.0 0.8 0.5 0.1 1.8 0.3 0.2 1.3 0.1 0.3 0.8 9.9 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 VIPR1 "HVR1, RDC1, VPAC1, VPAC1R" ENSG00000114812 "Vasoactive intestinal peptide receptor 1" P32241 3 42489299-42537573 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 83.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 27.2;RT4: 19.4;SK-BR-3: 11.1;WM-115: 35.3" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.2;intermediate monocyte: 2.6;MAIT T-cell: 1.9;memory CD4 T-cell: 4.8;memory CD8 T-cell: 1.9;myeloid DC: 3.9;naive CD4 T-cell: 5.5;naive CD8 T-cell: 1.7;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 32 "dendritic cells: 3.9;monocytes: 3.2;T-cells: 5.5" "Group enriched" "Detected in many" 5 "amygdala: 6.5;basal ganglia: 4.1;cerebral cortex: 9.2;hippocampal formation: 8.5" "Low region specificity" "Detected in all" HPA026777 Approved "HPA026777: AB_10604003" "unprognostic (9.02e-2)" "unprognostic (9.34e-3)" "unprognostic (3.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.28e-1)" "unprognostic (1.47e-2)" "unprognostic (8.89e-4)" "unprognostic (4.00e-3)" "unprognostic (1.03e-1)" "unprognostic (2.95e-2)" "unprognostic (1.28e-2)" "unprognostic (2.72e-1)" "unprognostic (1.82e-3)" "unprognostic (7.70e-2)" "unprognostic (1.69e-1)" "unprognostic (1.03e-2)" "unprognostic (1.05e-2)" 8.1 1.8 5.6 6.4 11.8 1.3 7.4 10.2 13.8 2.0 17.7 0.6 27.8 22.0 0.9 4.6 2.7 1.0 10.6 3.1 2.9 1.2 1.4 15.4 83.1 5.1 1.3 8.4 0.5 1.4 2.9 1.2 1.9 1.9 13.0 18.1 2.2 9.7 29.0 0.8 12.2 25.9 1.3 0.9 2.7 3.7 0.9 1.3 0.0 7.2 3.2 3.1 6.0 2.4 0.1 3.9 0.1 3.2 0.0 5.5 1.3 0.0 1.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.9 27.2 0.1 1.3 0.0 1.1 0.0 0.7 0.0 0.0 2.1 1.6 0.8 0.0 0.1 0.0 0.2 0.0 1.7 0.1 0.5 0.3 0.0 0.0 0.0 2.2 0.0 0.1 1.7 0.1 0.2 0.0 1.2 0.0 19.4 0.6 0.0 0.0 11.1 0.0 6.8 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.3 0.0 3.2 0.0 0.4 2.6 1.9 0.1 4.8 1.9 3.9 0.0 5.5 1.7 0.1 0.0 2.3 0.0 0.7 1.3 5.6 11.8 10.2 13.8 2.9 1.2 1.3 8.4 1.9 1.3 VIPR2 "VPAC2, VPAC2R" ENSG00000106018 "Vasoactive intestinal peptide receptor 2" P41587 7 159028175-159144957 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HeLa: 4.1;HMC-1: 6.3;MOLT-4: 8.6;U-266/70: 29.1" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 16 "plasmacytoid DC: 13.1" "Lineage enriched" "Detected in single" 16 "dendritic cells: 13.1" "Region enhanced" "Detected in some" "olfactory region: 33.2" "Low region specificity" "Detected in all" HPA062707 Approved Approved "Focal adhesion sites" "Focal adhesion sites" "HPA062707: " "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (4.26e-2)" "unprognostic (2.04e-2)" "unprognostic (6.31e-2)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (8.58e-2)" "unprognostic (2.32e-2)" "unprognostic (1.02e-1)" "unprognostic (9.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (8.89e-2)" 9.6 1.2 2.1 2.9 1.3 0.6 2.1 0.9 10.2 18.0 10.6 1.5 14.1 2.1 11.5 14.3 3.1 3.3 4.7 13.3 2.6 1.8 1.0 0.6 0.6 3.0 1.9 2.3 10.8 15.7 0.3 2.6 6.4 2.1 8.4 1.5 4.9 1.1 24.0 7.3 0.6 3.9 7.1 2.4 1.1 8.3 2.4 1.1 16.9 0.4 0.7 0.8 5.7 9.9 0.0 13.1 0.1 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 8.6 0.0 0.7 0.0 2.2 0.1 0.5 0.0 0.0 2.0 1.6 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 29.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.1 0.0 0.0 13.1 0.0 0.1 2.1 1.3 0.9 10.2 2.6 1.8 1.9 2.3 2.1 1.1 VN1R1 "V1RL1, VNR19I1, ZVNH1, ZVNR1" ENSG00000178201 "Vomeronasal 1 receptor 1" Q9GZP7 19 57454790-57457142 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 9.2" "Cell line enhanced" "Detected in some" "HEK 293: 6.1;U-266/70: 5.5;U-266/84: 6.5" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in some" "naive B-cell: 2.3" "Low lineage specificity" "Detected in single" HPA062209 Uncertain Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA062209: " "unprognostic (7.11e-2)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (1.51e-2)" "unprognostic (5.28e-2)" "unprognostic (1.01e-1)" "unprognostic (2.84e-2)" "unprognostic (1.65e-3)" "unprognostic (1.21e-2)" "unprognostic (5.41e-2)" "unprognostic (5.68e-2)" "unprognostic (2.73e-1)" "unprognostic (1.25e-2)" "unprognostic (4.59e-5)" 0.1 1.4 2.0 0.3 2.9 0.3 1.5 9.2 3.5 0.2 0.7 0.0 0.5 5.3 0.9 0.8 0.6 1.9 1.9 2.0 0.8 0.9 0.9 0.7 1.5 1.6 0.4 3.6 3.5 1.1 2.0 0.4 0.8 1.3 3.6 4.0 0.5 0.5 1.5 1.1 0.9 1.4 2.7 0.4 0.5 0.3 2.3 0.3 0.5 0.3 0.6 0.4 0.1 0.5 0.1 1.8 1.9 0.1 0.5 0.9 0.4 0.7 0.4 1.8 0.0 0.2 0.2 0.9 0.2 0.0 0.4 0.2 0.7 0.0 6.1 0.9 0.0 0.6 0.3 0.4 1.2 0.7 0.6 0.1 0.4 0.2 0.3 0.9 0.9 0.3 0.4 2.0 0.5 0.6 0.4 1.2 0.9 0.6 1.0 3.3 1.4 0.0 0.5 0.1 0.9 0.6 0.1 1.5 0.2 0.4 0.6 5.5 6.5 0.5 0.5 0.1 1.1 0.5 0.3 0.3 0.4 0.0 0.2 1.3 0.3 0.3 0.2 2.3 0.4 0.3 0.5 0.6 0.2 0.3 0.0 0.1 VN1R2 V1RL2 ENSG00000196131 "Vomeronasal 1 receptor 2" Q8NFZ6 19 53258292-53261837 "G-protein coupled receptors, Predicted membrane proteins" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 5.0;testis: 3.2" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA044551 Uncertain "HPA044551: " "unprognostic (9.54e-2)" "unprognostic (3.17e-1)" "unprognostic (1.06e-1)" 0.2 0.2 0.4 0.8 0.4 0.5 0.3 0.6 0.8 0.2 0.3 0.2 0.5 1.6 0.3 0.2 0.0 5.0 0.4 0.4 0.3 0.3 0.2 1.7 0.3 0.6 0.2 0.3 0.2 0.0 0.3 0.0 0.4 0.0 0.4 0.9 0.6 0.0 0.3 0.3 0.2 3.2 0.5 0.0 0.3 0.3 0.8 0.5 1.3 0.5 0.6 1.1 0.2 0.8 0.8 0.8 1.3 0.0 0.0 0.3 1.0 0.0 0.0 0.3 0.0 2.2 1.9 0.5 0.5 0.6 0.0 0.0 0.0 0.8 0.7 1.2 2.6 1.5 0.0 0.2 1.7 0.6 0.4 0.1 0.0 0.0 0.8 0.6 0.4 0.9 0.4 1.1 0.5 0.7 1.1 2.1 0.0 0.5 2.2 1.3 1.2 0.2 0.8 0.3 1.3 0.1 1.6 1.0 0.8 1.3 0.4 1.7 0.6 0.8 1.2 0.5 0.8 0.4 0.5 0.5 1.1 0.3 0.4 0.2 0.4 0.2 0.2 0.8 0.3 1.0 1.3 0.6 0.4 0.5 0.1 0.2 VN1R4 V1RL4 ENSG00000228567 "Vomeronasal 1 receptor 4" Q7Z5H5 19 53266676-53267723 "G-protein coupled receptors, Predicted membrane proteins" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 2.5" "Cell line enhanced" "Detected in single" "U-2 OS: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027018 Uncertain "HPA027018: AB_10603142" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 XCR1 "CCXCR1, GPR5" ENSG00000173578 "X-C motif chemokine receptor 1" P46094 3 46017024-46027742 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.5" "Cell line enhanced" "Detected in some" "Karpas-707: 5.5;RT4: 4.3;U-266/84: 4.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "myeloid DC: 7.2" "Lineage enriched" "Detected in single" 7 "dendritic cells: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013169 Uncertain "HPA013169: AB_1846211" "unprognostic (3.49e-3)" "unprognostic (4.23e-3)" "unprognostic (1.15e-2)" "unprognostic (5.91e-3)" "unprognostic (7.91e-2)" "unprognostic (8.53e-6)" "unprognostic (3.89e-6)" "unprognostic (9.27e-3)" "unprognostic (4.41e-3)" "unprognostic (3.40e-3)" "unprognostic (2.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.87e-1)" "unprognostic (5.98e-2)" "unprognostic (1.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.80e-1)" 0.7 0.5 0.4 4.0 0.5 2.5 0.7 0.4 0.5 1.1 2.5 0.1 0.1 1.1 0.6 4.9 2.5 0.7 3.3 0.9 0.4 0.4 0.8 0.7 1.8 9.8 0.4 0.1 0.9 0.6 0.0 0.5 9.4 0.2 0.5 0.8 1.7 2.1 0.2 0.6 7.6 3.3 1.1 0.5 6.8 0.8 0.7 0.1 27.5 0.8 6.3 5.1 1.0 1.2 0.1 7.2 0.9 0.3 0.3 0.7 0.6 0.1 1.9 0.8 0.0 0.0 0.0 1.6 0.7 1.8 0.0 0.0 1.6 0.0 1.5 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 1.3 3.1 0.0 0.9 0.0 1.0 1.0 5.5 0.0 1.8 0.9 0.0 0.0 0.0 1.0 0.0 0.6 0.7 4.3 0.4 0.0 0.0 0.5 0.1 0.5 0.1 0.0 0.9 2.2 0.4 0.2 2.6 4.5 1.4 3.1 0.0 0.4 0.9 0.1 0.3 0.7 0.1 0.1 0.0 0.1 0.6 7.2 0.1 0.1 0.4 0.7 0.3 0.3 0.2 0.1 0.6 0.4 0.5 0.4 0.5 0.4 0.4 0.4 0.1 0.2 0.1