Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" AADAC "CES5A1, DAC" ENSG00000114771 "Arylacetamide deacetylase" P22760 3 151814037-151828488 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 66.2;intestine: 81.7;liver: 123.1" "Cell line enhanced" "Detected in some" "A549: 11.7;ASC diff: 4.4;EFO-21: 6.3;HBEC3-KT: 5.6" "Cancer enriched" "Detected in many" 22 "liver cancer: 153.4" "Region enriched" "Detected in single" 7 "basal ganglia: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA002911 Approved "HPA002911: AB_1078074" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.11e-2)" "unprognostic (4.41e-2)" "unprognostic (9.23e-2)" "unprognostic (7.82e-2)" "unprognostic (2.15e-1)" "unprognostic (9.89e-2)" "prognostic favourable (5.58e-6)" "prognostic unfavourable (5.02e-4)" "prognostic unfavourable (2.19e-4)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" 3.9 66.2 0.1 0.1 1.6 0.0 2.1 0.1 0.1 0.1 26.1 0.5 0.4 29.6 0.1 0.3 0.3 0.2 4.3 0.2 0.1 0.0 0.1 123.1 1.7 0.1 0.1 0.1 0.1 22.7 0.0 0.1 1.7 0.2 0.3 0.0 0.1 0.3 0.1 0.2 1.7 81.7 0.1 0.1 0.1 7.3 0.3 0.1 0.1 0.2 4.8 1.3 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 4.4 0.2 0.3 0.0 0.0 0.1 0.0 1.1 0.1 0.2 6.3 0.0 0.4 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.7 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.2 0.3 0.2 0.4 2.1 0.0 2.2 0.2 1.9 0.3 0.1 0.0 0.0 0.0 2.5 0.0 2.4 1.3 0.0 0.4 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503633-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 57.8;intestine: 49.6" "Cell line enhanced" "Detected in some" "CACO-2: 29.4;HEK 293: 9.0;HEL: 16.3;Hep G2: 8.1;RPTEC TERT1: 11.3;SH-SY5Y: 36.0" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "MAIT T-cell: 19.2" "Group enriched" "Detected in many" 8 "NK-cells: 11.4;T-cells: 19.2" "CAB001716, HPA002199" Enhanced Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Nucleoplasm, Focal adhesion sites, Cytosol" "CAB001716: , HPA002199: AB_1844428" "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favourable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favourable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" 2.6 57.8 9.4 3.2 11.5 1.2 3.4 5.1 10.5 5.5 22.7 3.8 2.0 14.4 9.4 3.5 2.0 3.2 9.0 1.8 9.2 6.6 19.1 15.6 3.8 2.2 9.4 5.7 2.2 1.5 1.7 1.3 3.1 11.1 2.7 10.7 7.6 1.5 2.1 1.1 1.3 49.6 5.7 9.0 2.4 1.7 1.3 8.6 0.1 2.4 1.4 2.2 2.6 5.9 1.9 0.0 0.1 0.0 11.4 19.2 1.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 29.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 9.0 16.3 1.9 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 11.3 0.0 0.4 36.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.4 3.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 7.8 0.0 19.2 0.4 2.0 4.7 0.0 1.9 1.2 4.8 0.1 11.4 0.0 0.0 0.0 1.5 9.4 11.5 5.1 10.5 9.2 6.6 9.4 5.7 11.1 8.6 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401697-87480435 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease mutation, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 93.2" "Group enriched" "Detected in some" 5 "SH-SY5Y: 11.7;WM-115: 22.3" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 6 "memory B-cell: 4.9;naive B-cell: 11.4" "Lineage enriched" "Detected in many" 8 "B-cells: 11.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: , HPA053288: " "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.5 4.1 0.2 4.3 0.2 0.2 0.3 0.1 1.1 0.2 0.6 0.4 0.0 0.0 0.1 0.2 0.6 0.1 0.3 4.0 0.3 0.2 0.4 93.2 0.1 4.1 0.3 0.2 0.3 0.1 0.0 0.5 0.0 0.3 0.3 0.4 0.8 0.4 0.1 2.9 0.6 1.2 1.6 0.5 5.2 0.2 0.5 0.4 0.1 0.4 4.2 3.2 0.6 0.5 11.4 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.3 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 11.7 0.0 0.5 2.2 0.2 0.5 0.0 0.2 1.6 0.1 0.0 0.0 0.0 2.7 0.2 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.1 4.9 0.0 0.1 1.4 11.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.2 0.1 1.1 0.3 0.2 0.3 0.2 0.3 0.4 ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10" Q9NUJ1 3 111979010-111993363 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria "Intracellular and membrane" 85000 Mitochondria "HPA036991: , HPA036992: AB_10672345, HPA066081: " "unprognostic (1.65e-1)" "prognostic favourable (7.57e-4)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (1.14e-1)" "unprognostic (8.50e-2)" "unprognostic (1.69e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-2)" "prognostic favourable (4.72e-9)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (4.18e-3)" "unprognostic (2.76e-2)" 8.5 18.3 17.5 8.1 27.5 7.6 12.4 23.2 23.2 9.9 11.3 13.7 8.6 9.4 9.4 42.4 7.0 12.5 8.4 19.8 18.6 19.6 39.1 26.6 9.7 14.0 17.0 21.6 16.8 12.1 8.8 26.1 8.8 19.1 17.1 12.3 12.6 19.8 12.0 10.4 8.2 8.6 8.9 14.8 12.4 11.6 12.6 15.1 16.6 25.3 6.7 12.6 8.7 7.9 18.3 19.7 17.7 14.8 7.8 12.7 10.8 18.6 16.2 17.9 5.8 10.3 13.9 9.7 19.7 10.4 16.2 15.7 16.6 10.8 16.9 11.1 8.2 10.4 7.9 11.0 22.4 5.7 10.0 13.9 8.0 14.4 8.2 27.9 15.0 8.5 8.2 8.3 21.1 17.4 6.3 7.2 17.8 6.2 26.2 13.0 11.6 25.7 23.8 11.4 7.8 16.9 8.1 12.1 8.8 15.8 11.5 18.4 12.9 10.2 9.7 9.7 12.5 7.0 10.3 11.6 4.1 28.8 9.8 15.3 10.3 17.7 11.8 17.5 7.4 14.8 12.7 18.3 9.3 8.4 19.7 15.9 12.0 10.5 1.8 7.8 11.6 12.5 8.8 10.8 17.5 27.5 23.2 23.2 18.6 19.6 17.0 21.6 19.1 15.1 ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12" Q8N2K0 20 25294743-25390983 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease mutation, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 71.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain "HPA026866: AB_1844446" "prognostic unfavourable (3.81e-5)" "prognostic favourable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavourable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" 11.3 13.4 27.4 10.0 32.1 9.8 10.4 22.3 39.8 11.1 15.6 30.8 14.1 20.7 9.1 58.9 20.4 11.3 14.0 12.2 41.5 25.9 18.9 13.1 14.0 10.3 31.5 21.0 13.8 65.6 16.0 14.4 25.6 26.9 15.6 15.2 11.5 13.8 17.4 4.0 16.2 21.1 9.9 43.3 7.8 22.1 7.6 19.0 10.2 36.8 7.9 16.0 15.7 10.9 3.9 14.6 12.6 14.2 11.1 11.5 6.0 14.8 34.1 8.8 11.0 18.1 10.8 21.7 21.4 17.9 16.8 19.4 19.9 22.8 4.7 12.1 16.8 24.2 11.1 12.7 14.4 4.8 8.9 7.5 9.3 27.6 14.4 7.2 16.1 13.4 8.3 20.7 9.8 7.7 5.5 71.3 15.9 30.7 11.0 7.7 6.7 21.6 8.4 22.6 44.5 11.3 30.9 11.3 9.4 18.0 44.5 31.7 15.1 12.4 9.6 21.3 14.4 12.9 12.3 8.4 7.7 7.5 14.8 8.6 13.7 9.8 14.2 12.6 8.0 12.2 6.4 3.1 8.8 11.5 14.6 3.9 7.5 7.4 1.8 11.1 13.1 13.1 7.9 6.0 27.4 32.1 22.3 39.8 41.5 25.9 31.5 21.0 26.9 19.0 ABHD17A "C19orf27, FAM108A1, MGC5244" ENSG00000129968 "Abhydrolase domain containing 17A" Q96GS6 19 1876810-1885547 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043270, HPA047226" Uncertain Approved Vesicles Vesicles "HPA043270: AB_2678401, HPA047226: AB_2679991" "unprognostic (3.77e-2)" "unprognostic (1.85e-1)" "unprognostic (3.57e-2)" "prognostic favourable (1.73e-4)" "unprognostic (3.70e-2)" "prognostic favourable (6.46e-4)" "unprognostic (1.69e-2)" "unprognostic (1.92e-2)" "unprognostic (5.09e-1)" "unprognostic (1.44e-1)" "prognostic favourable (1.76e-5)" "unprognostic (1.29e-2)" "unprognostic (1.85e-3)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (3.17e-1)" "unprognostic (1.60e-2)" 28.1 11.9 26.6 8.9 23.9 10.0 6.8 16.4 29.4 9.0 14.1 15.3 10.3 16.5 8.8 7.0 9.9 7.1 11.7 12.9 30.9 14.4 11.9 8.2 13.0 9.1 19.0 16.7 9.4 16.6 3.8 7.7 13.4 13.2 13.9 2.1 8.4 21.0 11.2 47.4 20.7 15.8 5.2 25.5 25.7 23.3 12.1 7.9 10.9 11.4 9.6 7.1 6.3 7.3 4.5 1.5 5.9 1.5 4.7 8.5 1.0 16.6 5.7 1.7 6.5 3.0 3.8 13.1 11.2 3.4 3.1 3.0 2.7 2.9 8.2 4.6 2.4 10.4 1.1 4.3 0.1 18.8 24.8 6.0 2.2 7.4 4.4 6.0 20.6 4.0 3.5 1.7 1.2 6.5 10.3 9.2 2.2 9.4 10.8 11.9 12.7 13.0 12.7 5.8 12.2 2.2 3.4 7.8 17.8 5.9 6.3 10.7 6.6 11.0 12.3 3.7 8.7 15.0 10.9 37.1 22.2 6.8 8.4 8.1 6.1 2.5 1.5 5.9 8.5 0.9 6.2 4.5 3.9 5.5 1.5 2.4 4.1 4.4 1.7 4.7 1.0 1.5 3.5 1.0 26.6 23.9 16.4 29.4 30.9 14.4 19.0 16.7 13.2 7.9 ABHD17B "C9orf77, CGI-67, FAM108B1" ENSG00000107362 "Abhydrolase domain containing 17B" Q5VST6 9 71862452-71910931 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 46.2" "Cell line enhanced" "Detected in many" "REH: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047862 Uncertain "HPA047862: AB_10959595" "unprognostic (7.47e-2)" "unprognostic (4.41e-2)" "unprognostic (4.03e-3)" "unprognostic (5.59e-2)" "unprognostic (5.57e-2)" "unprognostic (8.53e-3)" "unprognostic (9.44e-2)" "unprognostic (6.84e-2)" "unprognostic (5.46e-2)" "unprognostic (3.44e-2)" "unprognostic (3.49e-2)" "unprognostic (1.74e-1)" "prognostic favourable (2.59e-4)" "unprognostic (4.33e-2)" "unprognostic (2.12e-1)" "unprognostic (3.06e-3)" "unprognostic (1.34e-2)" 7.7 6.6 16.5 6.9 25.0 18.0 8.2 14.4 21.6 9.0 12.0 43.3 2.3 18.1 9.5 4.6 13.5 9.6 9.1 5.8 23.6 13.8 13.4 13.6 7.5 10.8 44.0 13.6 7.6 6.4 12.7 5.8 7.8 24.3 11.0 11.2 9.0 9.4 5.1 13.6 11.2 14.9 9.4 30.4 8.9 8.9 11.1 38.2 46.2 8.8 3.6 10.7 11.8 8.8 7.2 5.7 8.1 3.8 6.6 4.9 1.7 6.4 6.2 14.2 8.2 7.4 4.6 12.5 7.1 7.8 6.2 5.3 1.8 4.0 15.6 6.6 4.8 12.8 13.8 4.7 7.2 8.1 8.2 9.1 10.5 6.0 5.2 10.7 14.9 5.7 6.6 5.5 5.0 8.0 7.4 7.1 5.2 2.9 27.8 8.6 21.5 8.8 37.3 10.9 0.1 7.1 13.0 9.5 11.0 7.5 8.1 6.1 2.6 7.8 6.4 6.0 7.8 11.1 5.7 7.0 8.2 12.3 4.7 7.7 3.0 8.1 3.8 4.1 3.1 1.4 3.0 4.2 3.8 4.3 4.8 7.2 3.2 4.5 2.9 6.6 1.3 5.7 4.9 1.7 16.5 25.0 14.4 20.8 23.6 13.8 44.0 13.6 24.3 38.2 ABHD17C FAM108C1 ENSG00000136379 "Abhydrolase domain containing 17C" Q6PCB6 15 80679684-80755621 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 34.6;SK-MEL-30: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048890 Uncertain "HPA048890: " "unprognostic (3.60e-1)" "unprognostic (5.07e-2)" "unprognostic (1.58e-1)" "unprognostic (2.19e-2)" "unprognostic (7.51e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (2.59e-2)" "unprognostic (5.08e-3)" "unprognostic (2.87e-1)" "unprognostic (1.23e-3)" "unprognostic (5.75e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" "unprognostic (1.89e-3)" 2.1 3.8 14.6 16.8 16.0 3.7 8.0 6.6 13.0 13.8 42.0 5.4 4.6 15.5 4.5 1.8 31.7 7.7 12.2 3.1 10.7 8.5 10.4 5.4 27.2 11.6 8.2 8.2 2.0 8.3 5.1 6.0 19.7 5.7 12.6 38.1 3.9 16.2 6.0 1.6 12.6 25.9 6.8 6.2 5.7 23.5 3.6 5.6 2.7 7.8 13.9 23.2 13.8 13.0 1.2 1.1 0.0 0.5 0.0 2.8 0.3 8.7 8.3 5.4 6.8 2.0 4.1 9.3 8.4 31.8 7.2 7.0 6.9 19.6 2.9 3.4 8.9 18.0 15.1 7.7 6.5 20.5 8.5 0.0 6.4 7.3 3.5 2.6 4.2 8.8 9.4 5.2 2.5 7.7 0.0 3.7 4.1 24.3 0.2 0.2 8.0 3.1 5.7 4.6 8.1 5.8 34.6 4.8 2.0 6.7 11.6 38.3 5.7 4.5 2.6 4.4 3.6 4.8 7.4 0.3 0.1 2.8 2.9 24.0 4.9 0.0 0.1 0.0 2.7 0.3 2.0 1.2 2.1 2.8 0.4 0.1 0.3 0.6 0.0 0.0 0.5 1.1 0.1 0.3 14.6 16.0 6.6 13.0 10.7 8.5 8.2 8.2 5.7 5.6 ABHD2 LABH2 ENSG00000140526 "Abhydrolase domain containing 2" P08910 15 89087459-89202360 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HEL: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 29.0;neutrophil: 22.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005999 Approved Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA005999: AB_1078080" "unprognostic (6.60e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.00e-2)" "unprognostic (2.16e-1)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (1.67e-1)" "unprognostic (3.34e-1)" "unprognostic (3.67e-3)" "unprognostic (3.41e-3)" "unprognostic (1.80e-1)" "prognostic favourable (2.18e-7)" "unprognostic (4.17e-1)" "unprognostic (3.07e-2)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" 13.2 24.8 14.8 9.5 19.3 15.6 11.7 25.2 23.4 10.7 16.1 12.0 6.5 23.4 18.2 34.7 9.0 12.1 32.2 24.5 12.2 11.3 11.8 76.4 22.2 11.2 11.1 14.8 13.1 28.3 11.2 18.1 5.6 19.8 22.9 9.6 22.6 11.8 10.0 19.3 7.5 18.5 11.4 8.3 14.2 35.8 42.9 7.6 7.7 8.6 8.1 12.1 13.5 10.4 1.1 3.0 29.0 7.0 4.7 3.5 2.5 8.0 15.5 3.8 4.1 7.5 10.2 2.1 5.4 16.2 5.2 4.9 3.9 14.0 2.3 6.3 6.7 10.7 8.4 6.6 7.3 12.0 3.8 83.5 3.6 2.9 3.9 5.7 19.7 5.2 4.7 18.5 11.9 6.3 7.4 7.2 14.2 3.3 3.5 1.4 1.7 4.6 5.1 8.0 17.4 6.9 12.6 6.6 9.9 10.3 4.9 8.6 5.4 4.5 9.6 18.3 6.2 6.6 13.6 5.9 11.7 2.7 14.9 5.3 14.2 3.1 5.6 29.0 1.6 4.8 0.9 1.1 1.5 1.5 3.0 1.1 1.4 1.5 22.7 4.7 7.0 2.4 3.5 2.5 14.8 19.3 25.2 23.4 12.2 11.3 11.1 14.8 19.8 7.6 ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3" Q8WU67 18 21650897-21704805 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 54.1;RPMI-8226: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA010729: AB_1844449" "unprognostic (1.46e-1)" "unprognostic (4.61e-2)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (8.46e-2)" "unprognostic (3.14e-3)" "unprognostic (3.54e-3)" "unprognostic (1.52e-1)" "prognostic unfavourable (8.52e-4)" "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.58e-2)" 9.2 5.4 12.0 14.2 10.7 8.6 20.7 19.5 11.1 6.4 34.2 4.8 5.1 23.8 6.0 5.4 12.7 7.8 13.5 7.1 8.8 8.5 8.7 21.7 12.8 21.3 11.5 5.0 9.4 8.8 10.7 11.8 10.8 16.6 6.9 37.1 14.7 10.3 4.1 10.1 3.8 45.3 5.5 12.3 17.9 19.0 4.4 10.8 20.9 12.9 6.7 13.7 9.2 25.5 7.1 6.1 33.0 23.3 7.1 17.6 9.1 7.4 5.4 5.3 3.4 3.4 2.2 0.0 4.9 2.0 3.5 4.8 5.6 7.7 21.4 9.0 1.6 24.8 8.6 4.0 4.9 13.4 6.0 2.3 9.1 9.6 5.2 10.1 7.8 2.0 4.8 5.2 2.4 2.3 5.9 12.8 3.1 3.0 9.7 11.3 2.6 12.8 54.1 4.0 60.2 9.7 7.2 4.5 2.0 11.2 10.0 2.8 3.1 17.9 1.8 3.4 4.9 6.0 7.5 14.4 9.3 22.1 4.4 13.3 7.8 29.1 10.2 11.4 11.1 17.9 8.5 7.1 10.0 10.6 6.1 5.1 8.2 10.3 33.0 7.1 23.3 4.2 17.6 9.1 12.0 10.7 19.5 11.1 8.8 8.5 11.5 5.0 16.6 10.8 ABHD6 ENSG00000163686 "Abhydrolase domain containing 6" Q9BV23 3 58237506-58295693 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 43.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017283, HPA073225" Uncertain Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA017283: AB_1844452, HPA073225: " "unprognostic (4.20e-2)" "unprognostic (7.92e-2)" "prognostic favourable (1.13e-4)" "unprognostic (2.35e-2)" "unprognostic (1.16e-2)" "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (1.15e-2)" "unprognostic (9.54e-2)" "unprognostic (1.11e-3)" "unprognostic (1.34e-2)" "unprognostic (1.94e-1)" "prognostic favourable (1.11e-11)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (2.72e-1)" "unprognostic (6.31e-2)" 8.3 10.0 11.6 4.6 14.0 1.0 5.8 17.7 22.5 3.7 8.1 30.0 10.3 26.3 4.7 10.8 4.8 6.9 4.4 4.1 19.0 9.2 24.3 43.4 6.3 5.2 18.6 12.2 4.1 2.4 4.8 15.2 4.8 19.0 4.4 8.1 10.5 3.0 12.9 3.1 17.2 33.5 6.8 24.0 22.8 9.0 3.1 14.3 2.0 6.6 2.1 5.4 4.6 4.1 3.9 7.0 2.1 9.3 0.7 2.6 1.1 2.1 8.0 1.2 5.3 15.1 2.7 14.0 5.6 5.1 5.9 8.1 4.2 2.9 4.0 0.5 3.1 6.3 5.4 2.5 5.3 6.9 2.7 3.4 5.4 5.8 5.1 1.0 18.4 2.6 11.6 5.4 2.7 3.3 4.1 9.4 4.8 1.6 7.0 0.4 3.9 17.7 2.6 2.4 9.1 9.1 2.9 7.0 2.8 6.2 3.4 11.6 2.3 2.8 3.5 4.3 4.7 10.6 6.6 2.8 8.0 0.2 11.0 10.3 5.8 0.0 2.8 2.1 2.1 9.3 2.0 3.9 1.2 2.6 4.6 3.0 1.2 1.5 0.0 0.7 6.2 7.0 1.4 1.1 11.6 14.0 17.7 22.5 19.0 9.2 18.6 12.2 19.0 14.3 AC008397.2 ENSG00000285188 "CAMP-specific 3',5'-cyclic phosphodiesterase 4C " Q08493 19 18207961-18255419 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 22.4;intestine: 15.6;pancreas: 14.2" "Cell line enhanced" "Detected in some" "BEWO: 3.6;U-2197: 1.6;U-87 MG: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA048975 Uncertain "HPA048975: " 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.2 1.9 15.6 0.0 0.0 1.3 1.1 3.6 4.0 1.0 22.4 0.6 0.0 0.6 0.0 2.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.8 0.0 0.0 1.7 0.0 2.1 1.1 3.7 0.0 8.0 0.6 0.0 0.4 7.1 0.2 0.0 0.0 0.4 0.8 4.1 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 3.6 0.1 0.0 0.0 0.2 0.0 0.3 0.3 0.3 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.9 0.0 0.0 0.2 0.4 0.0 0.8 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 1.6 0.0 0.3 0.2 0.1 4.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 205.6" "Group enriched" "Detected in some" 4 "ASC TERT1: 35.9;HUVEC TERT2: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "memory B-cell: 3.7" "Group enriched" "Detected in many" 23 "B-cells: 3.7;monocytes: 2.0;T-cells: 1.9" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" 121920000 92000000 Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: " "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 6.8 2.0 0.5 2.4 4.2 0.0 2.9 0.5 1.1 5.3 83.2 0.7 37.7 46.4 4.5 5.1 1.7 1.5 4.4 4.7 0.6 0.7 2.6 1.4 16.3 2.2 0.4 0.7 1.4 3.0 3.6 3.6 3.6 0.8 3.4 1.4 1.7 2.5 20.1 3.6 1.3 205.6 2.4 0.6 1.4 1.9 32.6 1.3 0.5 6.9 3.1 2.2 1.7 1.6 3.7 0.1 0.0 2.0 0.0 1.9 0.4 0.0 0.0 0.0 0.0 1.5 35.9 0.4 1.3 2.6 0.0 0.0 0.5 3.1 0.7 1.0 6.1 0.0 1.7 0.0 0.0 0.0 0.7 3.4 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 18.3 3.0 0.0 0.0 0.6 0.0 0.7 0.2 0.3 0.1 0.2 0.5 0.0 0.0 4.5 3.2 0.0 0.0 0.0 1.6 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.4 0.6 0.9 3.7 1.9 1.4 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.4 0.5 4.2 0.5 1.1 0.6 0.7 0.4 0.7 0.8 1.3 ACE2 ENSG00000130234 "Angiotensin I converting enzyme 2" Q9BYF1 X 15561033-15602148 "Enzymes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 122.0" "Cell line enhanced" "Detected in some" "BEWO: 2.4;HaCaT: 4.1;Hep G2: 2.4;NB-4: 2.2;RPMI-8226: 2.0;RT4: 2.4;SH-SY5Y: 2.8" "Cancer enhanced" "Detected in many" "renal cancer: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174" Enhanced "Secreted to blood" 85000 "CAB026174: , HPA000288: AB_1078160" "unprognostic (1.40e-1)" "unprognostic (7.26e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (2.51e-1)" "unprognostic (5.26e-2)" "prognostic favourable (4.21e-4)" "unprognostic (2.34e-2)" "unprognostic (6.74e-3)" "unprognostic (2.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "prognostic favourable (2.12e-5)" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (7.10e-2)" 4.5 0.4 0.2 0.8 0.2 0.0 2.3 0.2 0.2 0.4 49.1 0.2 2.3 46.0 0.4 2.7 1.2 0.6 16.4 10.5 0.2 0.1 23.2 1.2 0.8 0.6 0.2 0.2 1.3 1.6 0.0 0.2 1.0 0.2 0.5 1.3 0.2 1.1 1.2 0.7 0.2 122.0 0.3 0.2 0.2 0.5 17.9 0.2 0.2 4.5 0.5 0.2 0.4 0.9 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.4 0.0 0.7 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.6 0.0 4.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.2 0.0 0.0 2.0 0.4 2.4 0.6 2.8 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 ACER1 ASAH3 ENSG00000167769 "Alkaline ceramidase 1" Q8TDN7 19 6306142-6333629 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "esophagus: 14.3;skin 1: 38.2;tongue: 17.3" "Group enriched" "Detected in some" 7 "MCF7: 2.2;T-47d: 7.9" "Group enriched" "Detected in some" 7 "head and neck cancer: 1.0;melanoma: 2.2;prostate cancer: 0.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "unprognostic (1.13e-2)" "unprognostic (2.87e-4)" "unprognostic (5.04e-2)" "unprognostic (6.18e-2)" "unprognostic (8.16e-4)" "unprognostic (7.27e-4)" "unprognostic (2.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.99e-1)" "unprognostic (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.30e-5)" "unprognostic (2.11e-1)" "unprognostic (4.44e-2)" "unprognostic (4.22e-1)" "unprognostic (2.24e-1)" 0.1 0.0 0.1 0.1 0.1 0.0 2.2 0.1 0.1 3.8 0.1 0.1 0.1 0.0 0.4 0.1 14.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 1.1 0.0 0.1 1.4 0.1 0.2 38.2 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 17.3 3.5 0.1 2.2 0.6 0.4 0.4 0.2 1.0 3.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 7.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.1 0.2 0.0 3.6 0.1 3.5 1.6 0.0 0.6 2.3 2.3 0.4 1.0 0.2 0.4 2.0 0.7 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 ACER2 "ALKCDase2, ASAH3L, FLJ41587" ENSG00000177076 "Alkaline ceramidase 2" Q5QJU3 9 19409059-19452020 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 41.0;urinary bladder: 31.3;vagina: 40.6" "Group enriched" "Detected in many" 7 "BEWO: 16.4;RT4: 40.2" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "intermediate monocyte: 3.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.94e-1)" "unprognostic (2.29e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (2.03e-1)" "unprognostic (3.90e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (7.42e-2)" "unprognostic (8.46e-3)" 17.4 1.7 3.1 0.7 5.9 0.4 20.7 2.3 6.8 1.4 3.5 0.9 5.3 3.0 1.3 3.0 1.8 2.8 1.3 3.2 3.0 1.9 1.6 2.6 1.5 0.6 4.4 0.3 1.3 4.7 2.7 1.6 20.0 4.5 9.4 3.1 1.4 1.8 6.8 2.1 4.0 1.7 2.1 2.9 1.2 41.0 1.3 4.7 0.4 1.8 1.0 0.8 31.3 40.6 1.0 1.2 0.0 3.1 0.0 1.0 0.5 0.6 1.2 2.0 1.1 3.5 0.2 16.4 1.0 0.7 0.4 0.5 0.3 1.0 0.7 0.4 0.1 2.4 0.5 3.2 0.9 1.3 0.6 1.1 0.9 1.5 0.7 0.2 1.0 1.1 3.0 1.2 1.4 3.4 1.7 2.0 1.1 0.9 1.9 0.9 1.5 0.5 1.6 0.6 0.4 0.3 40.2 3.8 0.9 0.2 1.0 0.2 1.4 1.4 1.7 0.3 0.8 0.3 0.5 0.7 0.9 0.8 0.3 0.8 0.7 0.0 0.1 0.0 0.8 3.1 0.2 1.0 0.3 0.3 0.3 0.4 1.0 0.2 0.0 0.0 0.0 1.2 0.3 0.5 3.1 5.9 2.3 6.8 3.0 1.9 4.4 0.3 4.5 4.7 ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 43.8;skeletal muscle: 98.2" "Cell line enhanced" "Detected in some" "BEWO: 8.0;CACO-2: 12.6;K-562: 14.8;Karpas-707: 24.7;U-2 OS: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" 650000 "Golgi apparatus" Vesicles "HPA027098: " "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavourable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavourable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" 1.4 4.8 5.8 3.5 16.1 10.3 1.4 22.8 11.8 1.4 4.2 2.7 1.4 5.7 1.9 2.6 2.8 1.8 3.1 4.5 5.5 43.8 1.4 1.8 1.8 5.9 22.2 4.8 1.7 1.6 7.0 3.2 2.0 37.9 3.3 3.4 4.6 6.5 3.3 98.2 1.4 7.9 1.9 8.7 2.3 2.1 1.9 2.6 3.5 1.6 15.9 3.2 2.1 1.2 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.3 0.2 0.5 0.0 8.0 0.3 0.0 0.1 0.2 12.6 0.3 0.0 0.4 0.0 0.4 2.1 0.1 0.0 4.3 0.5 0.2 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.0 14.8 24.7 0.1 3.5 0.0 0.1 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 1.4 0.0 1.0 0.0 0.0 0.0 0.1 0.7 5.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 16.1 22.8 11.8 5.5 43.8 22.2 4.8 37.9 2.6 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537114-73543794 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 27.6" "Cell line enhanced" "Detected in many" "Hep G2: 17.9;T-47d: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA043705 Approved Approved Mitochondria Mitochondria "HPA043705: " "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favourable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 8.5 7.2 5.1 3.7 3.9 1.0 13.7 2.0 7.7 3.0 5.8 4.1 0.9 5.3 6.8 8.8 2.7 3.4 1.8 11.3 4.3 3.6 16.4 27.6 9.0 0.9 3.2 6.0 4.5 1.4 2.9 0.9 4.1 5.6 5.5 3.4 2.4 2.7 6.1 10.7 3.8 12.9 13.0 1.9 1.0 3.4 2.7 2.4 0.9 1.8 5.0 1.9 5.6 1.7 3.8 5.7 1.0 1.7 4.2 6.3 3.1 4.1 5.0 1.9 0.1 9.8 6.0 0.1 1.3 5.3 4.4 8.1 1.9 2.0 0.0 0.0 3.5 2.5 0.0 0.9 2.1 2.3 1.6 2.6 1.2 17.9 9.4 0.1 2.9 7.8 0.4 3.5 0.0 2.0 0.0 0.0 3.4 1.6 0.3 0.5 1.8 1.9 5.1 3.9 0.1 4.3 4.6 2.2 3.8 4.1 12.2 6.7 24.7 6.1 2.2 2.5 3.2 2.2 0.0 0.0 0.0 1.3 3.6 0.0 3.9 0.1 1.3 1.0 6.0 1.7 4.9 3.8 5.5 4.7 5.7 2.6 4.8 5.3 0.2 4.2 1.5 3.2 6.3 3.1 5.1 3.9 2.0 7.7 4.3 3.6 3.2 6.0 5.6 2.4 ACOT12 "Cach, STARD15, THEAL" ENSG00000172497 "Acyl-CoA thioesterase 12" Q8WYK0 5 81330005-81394179 "Enzymes, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 49.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.0;CACO-2: 2.4;Karpas-707: 1.8;SK-MEL-30: 4.1" "Cancer enriched" "Detected in single" 76 "liver cancer: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037723, HPA037724" Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA037723: AB_10672606, HPA037724: " "unprognostic (6.06e-2)" "unprognostic (1.39e-1)" "prognostic favourable (5.30e-4)" "unprognostic (7.68e-2)" "unprognostic (8.22e-2)" "unprognostic (5.68e-3)" "unprognostic (2.46e-1)" "unprognostic (6.86e-2)" "unprognostic (1.46e-2)" "unprognostic (3.07e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.2 49.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.4 0.1 0.0 0.1 2.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 60.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA043705, HPA060170" Enhanced Approved Mitochondria Mitochondria "HPA043705: , HPA060170: " "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favourable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 41.4 16.5 5.9 6.4 5.3 2.7 13.4 3.3 8.7 7.8 11.9 4.6 4.0 12.8 13.9 10.6 9.4 8.3 8.8 35.1 4.5 4.0 25.0 60.5 6.2 4.4 4.3 5.4 6.2 8.1 6.4 2.7 7.9 4.3 8.5 6.2 6.9 7.3 6.8 50.7 3.9 12.0 16.3 3.2 4.3 7.4 5.7 3.7 5.3 7.4 11.6 3.9 11.3 4.6 9.7 13.8 1.8 4.4 9.0 19.0 8.1 11.1 10.9 2.3 9.6 10.2 4.0 0.4 6.0 13.8 9.7 12.9 7.7 7.4 0.0 4.3 3.2 6.1 0.0 0.6 5.1 14.0 13.8 6.7 4.4 26.5 6.6 0.0 19.1 9.0 0.0 3.6 0.0 4.2 0.0 0.0 8.3 4.6 1.0 7.6 3.3 16.5 15.9 9.7 0.1 3.5 4.7 10.0 12.1 14.6 11.4 11.9 27.3 5.4 7.5 8.6 21.4 5.5 5.6 0.0 0.0 4.0 7.1 0.0 8.0 1.5 3.7 1.8 14.6 4.4 10.7 9.7 13.7 11.1 13.8 7.9 12.4 13.5 0.1 9.0 3.9 8.5 19.0 8.1 5.9 5.3 3.3 8.7 4.5 4.0 4.3 5.4 4.3 3.7 ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591706-73596496 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.1;SK-BR-3: 11.4;T-47d: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000779 Enhanced "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavourable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favourable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" 6.3 2.2 2.9 1.4 3.6 0.6 4.4 1.6 5.7 3.6 2.6 1.0 1.5 3.9 1.0 2.4 2.0 0.9 3.3 2.9 2.1 2.0 13.0 15.6 3.9 1.1 1.6 2.8 0.9 2.2 1.1 0.7 4.9 2.7 1.4 3.1 1.8 3.1 3.4 0.7 0.9 7.4 2.5 0.8 1.4 1.9 2.8 0.9 0.3 1.2 0.8 1.2 1.1 1.3 1.7 0.6 5.0 0.4 4.6 10.6 3.2 4.2 1.2 0.1 0.0 0.5 0.2 0.0 0.2 0.0 0.3 0.4 0.1 7.1 0.0 0.2 0.3 0.4 0.0 0.0 0.0 2.2 0.0 0.0 1.5 0.0 0.8 0.0 4.0 0.3 0.5 0.1 0.0 0.1 0.0 0.0 0.2 5.5 0.1 0.7 0.3 1.1 0.0 0.0 0.0 0.1 2.0 0.6 0.1 2.7 11.4 0.8 28.5 4.3 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 1.0 10.6 0.4 5.5 1.6 5.2 6.0 0.2 1.7 3.2 6.5 0.3 4.6 0.2 0.6 4.8 3.2 2.9 3.6 1.6 5.7 2.1 2.0 1.6 2.8 2.7 0.9 ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6394391 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "NK-cell: 20.5;plasmacytoid DC: 19.4" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025735, HPA025762" Enhanced Supported Nucleoplasm,Cytosol 29000 Cytosol Nucleoplasm "HPA025735: AB_1844523, HPA025762: AB_1844524" "unprognostic (3.94e-2)" "unprognostic (1.74e-1)" "unprognostic (7.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.10e-2)" "unprognostic (5.06e-2)" "prognostic unfavourable (2.31e-5)" "prognostic unfavourable (1.29e-4)" "unprognostic (2.35e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavourable (2.55e-6)" "unprognostic (2.68e-2)" "unprognostic (1.45e-1)" "unprognostic (9.06e-2)" "unprognostic (3.72e-2)" 4.7 13.3 25.8 10.8 29.8 7.7 3.9 23.9 50.0 4.4 18.3 11.3 0.5 33.2 5.1 3.8 14.3 4.4 5.3 6.3 27.8 43.9 29.4 9.1 8.6 12.3 36.0 20.7 5.3 4.0 1.9 18.5 7.4 49.9 5.6 13.5 6.6 4.1 4.9 1.5 9.4 33.2 14.3 14.2 8.9 6.2 13.1 6.9 9.0 2.3 6.5 11.6 9.1 6.6 1.0 19.4 0.4 0.6 20.5 4.4 2.8 23.4 20.4 20.2 21.7 4.6 7.7 7.6 20.2 10.5 30.0 18.0 70.5 7.6 28.7 14.9 16.4 23.2 32.5 54.0 11.3 25.2 28.4 15.1 16.2 24.9 19.0 17.6 12.6 6.8 10.3 24.8 29.4 16.8 12.3 6.2 15.8 27.3 36.8 18.7 10.1 47.4 44.1 23.2 19.4 16.8 9.0 11.0 31.3 18.2 28.0 64.4 9.9 8.3 27.2 27.3 16.0 27.1 31.9 5.2 21.4 40.4 17.3 30.9 16.6 0.0 0.1 0.1 4.1 0.6 1.0 1.0 3.4 3.6 2.9 0.4 1.2 2.3 0.4 20.5 0.5 19.4 4.4 2.8 25.8 29.8 23.9 50.0 27.8 43.9 36.0 20.7 49.9 6.9 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857406 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favourable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 7.0 22.6 23.5 10.9 24.3 16.5 8.7 14.4 32.6 6.8 17.1 13.5 9.9 23.3 6.5 13.1 15.8 12.2 10.1 27.0 22.8 19.3 15.3 19.0 9.7 12.1 22.1 19.0 8.3 17.4 5.9 11.4 8.1 19.5 9.6 14.3 10.4 14.4 7.3 21.7 16.7 22.2 7.3 14.6 9.1 16.7 12.8 11.1 17.1 12.4 8.6 12.2 10.9 7.2 20.5 27.0 31.0 26.2 11.2 22.5 18.8 7.6 9.2 3.1 6.3 8.9 5.4 5.5 5.2 4.2 7.3 6.8 13.4 10.7 9.6 23.6 7.1 15.0 6.0 13.0 2.5 7.1 10.6 9.6 12.4 12.8 8.0 9.1 9.0 6.3 9.9 7.0 5.0 4.5 8.5 11.9 5.1 21.5 13.0 11.9 5.6 24.5 6.3 5.8 17.1 7.7 8.7 10.9 5.1 11.5 29.4 17.8 16.1 22.5 5.1 18.1 4.0 9.3 8.6 10.1 15.0 6.0 22.4 9.6 9.6 20.0 26.2 31.0 18.8 25.0 17.1 20.5 18.1 17.0 27.0 19.3 16.1 17.3 18.7 11.2 23.4 17.0 22.5 18.8 23.5 24.3 14.4 32.6 22.8 19.3 22.1 19.0 19.5 11.1 ACP1 "HAAP, LMW-PTP, LMWPTP" ENSG00000143727 "Acid phosphatase 1" P24666 2 264140-278283 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016754 Approved Approved Nucleoplasm,Cytosol 3700000 Nucleoplasm Cytosol "HPA016754: AB_1844505" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (6.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.43e-1)" "prognostic unfavourable (6.67e-6)" "unprognostic (2.45e-1)" "prognostic unfavourable (3.04e-4)" "unprognostic (9.72e-3)" "unprognostic (4.89e-2)" "unprognostic (2.71e-2)" "unprognostic (7.10e-2)" "unprognostic (2.88e-2)" "unprognostic (3.39e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" 22.3 59.7 38.0 20.8 40.3 38.0 33.0 27.9 43.7 23.1 29.7 27.4 24.4 31.1 25.2 36.2 24.8 29.5 26.9 27.4 34.6 33.7 42.1 54.8 24.7 29.4 31.5 34.6 33.7 53.0 28.4 43.9 39.7 39.7 27.0 32.8 28.5 46.0 23.8 35.4 21.6 34.5 24.2 28.6 28.1 34.2 38.3 21.2 33.0 32.5 32.8 29.8 22.7 20.3 33.9 20.3 17.3 23.0 35.3 41.0 33.1 17.6 26.4 41.1 22.6 18.7 18.7 33.5 21.5 22.9 21.5 19.1 36.1 17.8 11.1 16.8 20.1 17.4 39.9 23.3 19.4 27.0 40.7 32.5 23.9 79.1 25.9 36.9 18.7 19.0 21.3 20.1 24.9 24.4 32.8 21.7 25.4 24.0 39.7 35.7 49.7 29.8 26.3 41.8 25.4 33.6 25.3 44.9 44.5 13.4 31.7 43.0 18.8 19.8 20.1 23.7 15.8 19.5 32.4 29.5 58.6 34.7 28.1 32.0 27.9 17.3 19.8 17.1 30.1 22.7 39.7 33.9 34.3 34.4 17.7 31.1 41.0 39.7 3.5 35.3 23.0 20.3 35.6 33.1 38.0 40.3 27.9 43.7 34.6 33.7 31.5 34.6 39.7 21.2 ACP2 LAP ENSG00000134575 "Acid phosphatase 2, lysosomal" P11117 11 47239302-47248906 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 30.3" "Lineage enriched" "Detected in all" 5 "monocytes: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" 8100 "unprognostic (5.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.86e-2)" "prognostic favourable (1.04e-4)" "unprognostic (7.90e-3)" "unprognostic (2.93e-1)" "unprognostic (6.16e-3)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (3.28e-3)" "unprognostic (2.64e-3)" "unprognostic (5.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (8.68e-3)" "unprognostic (1.57e-1)" 15.7 23.6 13.1 13.9 13.6 3.6 13.0 12.5 19.5 11.3 15.4 11.7 15.4 26.9 10.5 20.0 8.9 9.3 12.4 18.1 14.4 18.2 18.7 65.4 13.3 40.7 11.8 12.7 8.1 36.2 13.6 13.8 31.3 12.2 15.3 11.7 16.4 32.3 18.5 10.1 7.0 24.4 10.8 11.0 18.9 14.2 14.6 7.1 10.0 12.4 9.6 9.7 14.3 8.0 1.0 6.6 4.6 30.3 3.8 5.6 4.2 6.7 14.0 13.6 12.0 12.2 6.1 10.5 11.1 19.9 20.4 21.3 9.6 11.1 1.8 9.2 14.2 10.0 7.1 10.3 9.9 34.6 12.2 4.5 20.6 10.1 17.0 6.7 11.7 14.9 6.5 10.6 6.2 14.7 8.2 14.6 13.3 10.9 5.5 6.0 9.4 8.5 4.3 18.4 14.7 15.2 15.7 7.2 11.2 15.4 34.3 7.9 20.9 5.9 8.7 10.4 8.7 13.5 15.8 12.2 15.7 1.5 15.3 3.4 15.8 4.6 7.2 3.0 5.6 30.3 4.4 1.0 3.5 5.0 6.6 0.7 3.1 2.7 1.2 3.8 19.5 0.2 3.6 4.2 13.1 13.6 12.5 19.5 14.4 18.2 11.8 12.7 12.2 7.1 ACP4 ACPT ENSG00000142513 "Acid phosphatase 4" Q9BZG2 19 50790415-50795224 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Hydrolase "Amelogenesis imperfecta, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 4.2;testis: 4.0" "Cell line enhanced" "Detected in some" "HEK 293: 4.3;Karpas-707: 2.8;U-266/84: 5.3" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (9.41e-2)" "unprognostic (1.86e-1)" "unprognostic (4.00e-3)" "unprognostic (3.70e-3)" "unprognostic (7.62e-2)" "unprognostic (3.18e-2)" "unprognostic (3.89e-3)" "unprognostic (5.46e-2)" "unprognostic (2.47e-1)" "unprognostic (5.59e-2)" "unprognostic (3.96e-1)" "unprognostic (1.45e-1)" "unprognostic (2.37e-3)" "unprognostic (2.36e-1)" "unprognostic (4.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.5 0.3 0.8 0.0 0.5 0.2 0.9 1.6 0.0 0.0 1.0 0.5 0.0 0.0 0.0 2.1 0.2 0.8 0.1 0.0 0.5 0.0 0.0 0.0 1.5 4.3 0.1 1.3 0.6 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.0 0.8 0.6 1.3 0.5 1.5 0.9 0.4 0.6 0.0 1.5 0.4 0.6 0.3 0.3 0.7 0.1 1.0 0.0 0.7 0.6 0.8 0.3 0.7 5.3 0.6 0.7 0.9 0.3 0.0 0.1 0.0 0.2 0.5 0.8 0.8 0.6 0.5 0.0 0.9 0.8 0.5 0.0 0.3 0.2 0.3 0.1 0.0 ACP5 "HPAP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574660-11579008 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 117.9;lung: 151.9" "Cell line enhanced" "Detected in some" "BEWO: 14.3;RPMI-8226: 13.6;SK-MEL-30: 40.4;U-138 MG: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "memory B-cell: 51.4" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002584, HPA057655, HPA059463" Enhanced Approved Cytosol "Intracellular and membrane" 3700000 Cytosol "CAB002584: AB_564039, HPA057655: , HPA059463: " "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" 117.9 2.8 0.9 21.1 1.1 1.4 7.7 0.7 1.0 11.9 10.2 1.2 2.1 7.7 7.7 6.5 12.1 3.5 9.1 6.8 0.9 0.4 28.0 16.3 151.9 30.8 1.0 1.0 13.2 8.7 0.2 1.6 9.2 1.2 6.4 8.7 19.1 8.6 2.8 3.0 10.4 15.6 3.3 1.9 20.7 15.0 3.5 0.7 9.2 2.2 8.2 18.4 11.4 10.1 51.4 13.9 16.8 9.4 2.6 16.0 8.1 3.2 0.4 0.0 0.0 0.2 0.0 14.3 0.4 9.6 0.0 0.0 0.0 0.1 0.4 0.6 2.8 0.1 0.0 1.4 0.0 3.6 0.3 0.1 0.0 1.7 0.5 0.0 0.2 0.0 1.1 0.1 0.0 0.0 10.0 0.0 0.0 0.7 0.3 0.5 0.3 0.2 0.1 0.7 13.6 0.0 0.1 0.2 0.3 0.0 0.0 40.4 0.0 0.1 0.3 38.0 0.4 0.7 0.1 0.2 1.8 0.2 7.8 0.0 1.2 0.0 9.4 16.8 4.1 9.1 2.1 51.4 6.4 4.7 1.7 23.5 8.3 4.7 2.6 2.6 8.7 13.9 16.0 8.1 0.9 1.1 0.7 1.0 0.9 0.4 1.0 1.0 1.2 0.7 ACP6 "ACPL1, LPAP" ENSG00000162836 "Acid phosphatase 6, lysophosphatidic" Q9NPH0 1 147629652-147670496 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 26.6;RPTEC TERT1: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028560 Uncertain "Intracellular and membrane" 64000 "HPA028560: AB_10602427" "unprognostic (3.17e-2)" "unprognostic (3.01e-2)" "unprognostic (3.50e-1)" "unprognostic (1.87e-2)" "unprognostic (3.85e-1)" "unprognostic (8.50e-3)" "unprognostic (3.36e-3)" "unprognostic (1.00e-1)" "unprognostic (6.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (3.94e-1)" "unprognostic (8.07e-2)" "unprognostic (1.26e-1)" "prognostic favourable (6.44e-4)" 6.0 14.5 8.8 6.6 10.7 4.7 19.3 10.5 9.1 12.6 10.5 7.6 13.1 7.7 10.0 17.6 8.1 13.9 13.6 8.5 13.0 6.0 17.0 13.3 7.6 3.8 10.2 8.0 11.6 18.5 18.1 22.5 4.4 11.6 13.6 10.2 12.7 12.3 19.2 7.6 9.2 8.9 9.7 11.2 6.6 12.8 8.2 12.7 10.8 20.7 5.8 9.7 16.8 6.9 2.9 4.8 11.5 2.2 0.3 12.4 2.6 7.9 3.2 2.8 4.9 1.8 1.7 7.9 1.8 5.7 5.8 6.9 3.9 12.3 2.3 6.9 3.9 13.7 3.7 12.2 6.1 3.1 6.2 8.2 4.7 7.2 5.3 1.5 0.3 2.6 9.1 3.0 6.1 5.8 3.8 1.3 6.5 5.9 6.0 3.8 6.6 24.4 4.4 2.4 26.6 47.0 15.7 2.3 2.8 6.7 4.8 13.5 7.9 2.2 4.1 1.8 3.5 0.3 5.7 5.2 7.7 1.0 3.4 0.1 9.9 0.0 2.2 11.5 4.3 0.7 7.5 2.5 7.2 5.8 4.8 2.9 8.0 6.9 3.3 0.3 0.3 3.0 12.4 2.6 8.8 10.7 10.5 9.1 13.0 6.0 10.2 8.0 11.6 12.7 ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 15.2;lymphoid tissue: 6.1;skin 1: 14.1;tongue: 5.5" "Cell line enriched" "Detected in some" 5 "U-87 MG: 31.2" "Group enriched" "Detected in some" 5 "cervical cancer: 0.8;head and neck cancer: 2.6;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" "HPA042613: AB_10963214" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-3)" "unprognostic (1.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (4.94e-3)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" "unprognostic (1.51e-5)" "unprognostic (4.36e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-2)" "unprognostic (2.42e-1)" 0.3 0.3 1.6 0.3 5.5 0.3 1.0 15.2 5.4 0.9 0.3 4.2 0.3 0.4 0.4 1.4 1.1 0.3 0.9 0.3 2.5 1.2 0.3 0.3 0.4 0.3 6.5 0.7 0.3 0.3 0.3 0.0 0.3 5.2 1.2 0.3 0.0 0.6 0.3 0.3 14.1 0.3 0.3 4.1 0.3 0.6 0.4 5.3 0.0 0.3 5.5 6.1 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.5 0.3 3.5 0.0 0.0 0.0 0.2 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.4 0.2 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.2 0.8 0.0 0.0 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.5 15.2 5.4 2.5 1.2 6.5 0.7 5.2 5.3 ACPP "ACP-3, ACP3, PAP" ENSG00000014257 "Acid phosphatase, prostate" P15309 3 132317367-132368298 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "prostate: 345.2" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.2;NB-4: 7.7;RPMI-8226: 32.3;U-698: 9.4;U-87 MG: 9.0" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "eosinophil: 43.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" 9200 "CAB000071: , HPA004335: AB_1079684, HPA063916: " "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" 0.4 0.6 0.4 0.7 1.6 1.4 0.8 0.3 0.7 3.9 0.4 0.2 0.0 0.4 0.3 2.5 14.7 0.6 0.2 0.9 0.3 0.3 6.2 0.3 2.0 2.7 0.6 0.8 0.4 0.8 0.5 0.3 5.3 0.7 345.2 0.7 0.8 9.1 0.2 0.3 2.5 0.4 0.4 2.2 1.0 0.5 1.0 0.6 0.2 1.3 6.6 6.8 0.5 1.5 0.2 11.2 43.1 9.7 0.9 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.6 7.0 0.1 10.2 0.0 0.0 0.2 0.2 5.7 0.4 0.0 2.9 0.0 0.0 0.0 0.0 0.3 1.1 0.2 0.1 0.1 4.1 0.1 0.6 0.8 0.0 0.0 0.0 0.1 1.6 0.1 0.1 0.0 7.7 0.4 1.2 0.0 0.0 32.3 3.1 3.8 0.0 2.5 0.0 1.2 0.3 0.2 3.7 0.0 0.0 0.1 1.5 0.0 0.4 0.2 9.4 9.0 7.3 0.1 0.0 9.7 43.1 0.0 8.6 0.0 0.2 0.0 0.0 11.2 0.0 0.0 0.0 8.5 0.9 7.7 0.8 0.0 2.9 0.4 1.6 0.3 0.7 0.3 0.3 0.6 0.8 0.7 0.6 ACR ENSG00000100312 Acrosin P10323 22 50738196-50745334 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "testis: 106.3" "Cell line enhanced" "Detected in some" "Hep G2: 1.7;HUVEC TERT2: 1.1;NTERA-2: 1.7;TIME: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA048687 Enhanced "Secreted in male reproductive system" "HPA048687: " "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "unprognostic (6.27e-3)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (3.30e-3)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (1.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" 0.9 0.0 0.2 0.2 0.3 0.0 0.6 0.2 0.3 0.2 0.2 0.2 0.2 0.1 0.3 0.7 0.2 0.4 0.2 0.2 0.2 0.0 0.2 0.3 0.6 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.4 0.2 0.2 0.2 0.2 0.2 0.2 1.2 0.0 106.3 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.6 0.2 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 1.4 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.3 0.2 0.0 0.2 0.2 0.2 0.2 ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983278-51989202 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "intestine: 53.3;kidney: 91.6;liver: 77.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "CAB003695, HPA036174, HPA036175" Enhanced 28000000 "CAB003695: AB_425286, HPA036174: , HPA036175: " "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-3)" "unprognostic (3.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.08e-2)" "unprognostic (2.36e-2)" "unprognostic (2.70e-2)" "prognostic favourable (2.93e-4)" "unprognostic (3.57e-1)" "unprognostic (3.75e-1)" "unprognostic (7.88e-2)" "prognostic favourable (6.77e-4)" 4.4 8.5 2.5 3.9 3.0 1.5 4.4 1.5 3.3 3.2 24.9 4.1 9.8 34.5 1.9 7.9 3.8 3.0 8.4 4.1 2.3 1.8 91.6 77.8 3.5 6.3 2.8 2.9 2.1 9.0 6.2 1.9 4.3 2.9 3.7 6.2 6.6 9.4 9.2 7.6 2.6 53.3 2.1 3.5 3.4 4.9 1.5 1.7 0.6 5.9 6.7 4.1 3.3 2.5 5.0 12.1 3.8 10.0 12.1 6.4 4.5 3.9 8.0 3.9 10.9 9.0 12.2 12.9 4.2 7.9 9.3 5.1 12.5 20.9 2.5 3.6 7.3 4.9 4.0 25.7 3.7 7.0 5.1 9.0 4.6 38.5 16.7 6.0 5.8 14.0 21.3 8.2 22.2 3.5 13.5 8.0 9.1 11.2 0.0 11.0 5.7 13.6 3.1 3.3 22.6 24.4 15.1 5.5 5.0 5.3 17.6 9.3 14.2 7.9 1.7 6.7 6.4 8.3 5.0 21.0 4.9 3.8 7.9 12.6 8.1 3.8 10.0 0.2 6.4 9.0 3.6 5.0 2.0 2.8 12.1 4.0 3.3 4.0 0.0 12.1 3.4 1.9 2.7 4.5 2.5 3.0 1.5 3.3 2.3 1.8 2.8 2.9 2.9 1.7 ACY3 "ACY-3, HCBP1, MGC9740" ENSG00000132744 "Aminoacylase 3" Q96HD9 11 67642555-67650659 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 72.2;kidney: 28.9" "Cell line enhanced" "Detected in some" "CACO-2: 6.0;CAPAN-2: 9.4;Daudi: 34.2;RPMI-8226: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 21.1" "Group enriched" "Detected in many" 6 "dendritic cells: 5.9;monocytes: 21.1" "Low region specificity" "Detected in all" "HPA039219, HPA048187" Enhanced "HPA039219: AB_10671872, HPA048187: AB_2680306" "unprognostic (8.37e-3)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "prognostic favourable (4.80e-4)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (1.38e-2)" "unprognostic (1.43e-1)" "unprognostic (7.37e-4)" "unprognostic (2.44e-3)" "unprognostic (1.15e-1)" "unprognostic (3.21e-1)" "unprognostic (2.63e-3)" "unprognostic (1.07e-1)" "unprognostic (8.24e-2)" "unprognostic (2.68e-2)" "unprognostic (1.48e-3)" 0.1 0.1 3.4 1.8 5.5 0.6 0.5 0.8 7.8 5.5 13.0 15.3 0.2 38.2 0.3 2.1 0.7 0.4 6.1 0.1 3.1 2.9 28.9 18.3 0.2 3.1 4.6 5.1 0.1 11.2 0.0 0.3 0.1 7.1 0.4 2.2 0.3 1.2 0.2 0.1 0.1 72.2 0.1 5.2 0.9 5.9 0.1 2.8 0.7 0.2 0.0 4.2 0.2 0.2 1.1 5.9 0.0 21.1 2.3 0.9 1.2 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 9.4 34.2 0.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 3.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 1.5 0.0 0.0 1.1 0.0 5.9 0.0 0.0 0.0 0.1 0.2 0.8 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.8 0.3 0.0 0.5 0.0 0.1 4.9 0.5 1.0 0.2 0.1 2.6 1.1 0.9 0.6 0.0 2.3 21.1 5.9 0.0 1.2 3.4 5.5 0.8 7.8 3.1 2.9 4.6 5.1 7.1 2.8 ACYP1 ENSG00000119640 "Acylphosphatase 1" P07311 14 75053221-75069483 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034944 Approved Approved Nucleoplasm,Cytosol 92000 Cytosol Nucleoplasm "HPA034944: AB_10669898" "prognostic favourable (1.17e-4)" "unprognostic (3.83e-3)" "unprognostic (1.92e-1)" "unprognostic (5.90e-2)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "prognostic unfavourable (6.14e-7)" "unprognostic (5.48e-2)" "unprognostic (4.40e-1)" "unprognostic (1.64e-2)" "unprognostic (1.37e-3)" "unprognostic (3.56e-2)" "unprognostic (4.74e-2)" "unprognostic (6.69e-3)" "unprognostic (9.39e-2)" "unprognostic (1.07e-1)" "unprognostic (5.32e-3)" 8.7 27.4 23.0 13.9 20.4 12.7 16.2 24.0 25.2 10.6 14.9 14.8 14.3 11.3 10.2 26.9 11.6 21.4 7.1 10.8 19.9 30.2 12.2 5.2 10.9 17.6 28.7 19.3 9.1 7.0 8.9 38.2 10.4 24.4 10.0 19.8 9.4 9.7 12.9 22.3 24.4 11.3 11.4 27.5 10.9 14.0 16.7 22.9 8.3 20.2 10.3 19.0 7.5 12.0 10.6 7.6 12.3 6.6 10.0 17.8 5.1 24.6 13.6 19.6 12.0 8.0 9.3 10.9 14.2 5.5 14.4 20.6 13.7 27.8 27.3 8.7 5.9 22.3 12.9 6.3 23.7 39.6 15.9 17.7 35.8 9.7 4.7 11.1 18.5 5.1 9.1 20.0 10.3 19.0 13.9 33.0 19.0 16.9 24.9 20.8 6.0 13.7 20.0 25.9 12.7 20.4 13.1 36.0 14.6 9.7 6.6 22.0 14.7 11.0 8.9 9.9 18.4 19.9 15.2 7.9 15.9 28.6 15.1 13.1 10.6 3.9 2.2 12.3 8.6 4.3 9.7 10.0 14.5 9.9 3.8 10.6 12.2 11.3 0.9 10.0 6.6 7.6 17.8 5.1 23.0 20.4 24.0 25.2 19.9 30.2 28.7 19.3 24.4 22.9 ACYP2 ENSG00000170634 "Acylphosphatase 2" P14621 2 53970838-54305300 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 116.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035301 Uncertain Approved Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA035301: AB_10670291" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (6.90e-3)" "unprognostic (6.21e-2)" "unprognostic (2.03e-3)" "unprognostic (3.17e-1)" "unprognostic (5.22e-2)" "unprognostic (7.83e-3)" "unprognostic (3.64e-3)" "unprognostic (1.16e-1)" "unprognostic (6.66e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" "unprognostic (2.24e-2)" 12.9 24.0 31.0 4.6 33.9 5.6 10.1 15.5 29.3 6.7 6.2 19.4 4.4 6.2 6.7 10.5 6.6 7.1 7.3 39.6 29.1 28.4 8.8 18.7 7.2 7.5 35.7 18.2 5.7 10.3 9.1 9.7 5.9 28.1 10.4 4.8 6.3 11.5 8.4 116.4 6.6 5.6 6.9 35.7 7.8 7.5 6.5 22.7 3.5 8.2 22.9 6.4 8.2 4.1 20.9 23.7 24.1 10.2 12.6 15.9 8.9 7.6 4.3 4.5 3.7 16.6 13.1 4.1 9.2 6.9 5.7 5.0 1.0 5.6 14.9 24.4 9.1 6.6 2.4 7.7 5.3 12.9 10.2 11.5 4.6 11.4 6.8 9.6 5.6 9.5 14.5 4.1 6.8 2.6 4.7 8.0 12.1 4.9 5.9 11.9 5.2 5.3 4.7 4.3 8.4 13.5 7.0 13.2 8.7 11.1 7.0 4.1 2.6 8.8 9.2 8.1 7.8 3.5 8.5 16.9 9.3 8.3 11.7 16.4 8.9 24.1 10.2 19.8 13.4 9.0 11.9 20.9 13.4 12.7 14.7 19.7 15.9 13.4 8.5 12.6 8.8 23.7 11.6 8.9 31.0 33.9 15.5 29.3 29.1 28.4 35.7 18.2 28.1 22.7 ADA ENSG00000196839 "Adenosine deaminase" P00813 20 44619522-44652233 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease mutation, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 64.0;intestine: 142.2;lymphoid tissue: 99.0" "Cell line enriched" "Detected in many" 8 "MOLT-4: 197.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 64.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001399, CAB004307, HPA023884" Enhanced Supported "Plasma membrane,Cytosol" 650000 "Plasma membrane" Cytosol "CAB004307: AB_626634, HPA001399: AB_1078099, HPA023884: AB_1844573" "unprognostic (4.30e-2)" "unprognostic (6.89e-2)" "unprognostic (3.96e-2)" "prognostic unfavourable (1.23e-7)" "unprognostic (9.33e-2)" "unprognostic (9.07e-3)" "prognostic unfavourable (6.77e-5)" "prognostic unfavourable (2.20e-4)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-1)" "prognostic unfavourable (2.94e-14)" "unprognostic (2.29e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" 8.1 3.2 2.5 5.4 6.5 5.3 5.1 0.9 5.0 2.8 7.4 5.0 1.8 142.2 1.7 3.4 4.6 2.4 3.0 9.2 2.7 0.8 1.3 2.1 2.8 8.9 3.6 2.3 1.2 2.4 0.8 0.3 1.8 3.9 1.8 1.5 0.7 2.6 1.3 2.0 2.8 5.0 2.1 1.3 9.5 19.7 1.6 6.1 99.0 2.8 2.1 7.6 3.6 2.6 1.3 41.6 0.5 64.0 16.9 10.3 9.6 1.4 3.9 2.0 1.3 3.9 5.4 3.3 1.4 0.8 1.4 1.0 1.8 1.5 4.0 1.7 1.8 0.2 1.4 5.8 0.8 0.3 1.8 0.8 0.7 1.4 1.6 0.6 2.1 26.1 2.5 0.5 0.9 5.4 2.0 3.3 0.6 3.4 197.1 2.9 0.5 1.4 10.6 2.8 9.8 0.2 0.0 0.0 0.9 2.1 0.4 2.5 0.4 1.9 1.7 1.0 2.0 2.2 0.2 4.3 2.7 8.3 0.3 3.3 0.9 0.0 1.8 0.2 8.7 30.7 5.7 1.3 7.3 10.3 6.8 1.0 5.7 8.1 0.5 16.9 64.0 41.6 5.3 9.6 2.5 6.5 0.9 5.0 2.7 0.8 3.6 2.3 3.9 6.1 ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17221989 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 63.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.0;EFO-21: 11.5;HUVEC TERT2: 12.4;Karpas-707: 22.1;MOLT-4: 20.5;U-266/70: 12.6;U-937: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" 50000000 "HPA007888: AB_1078495" "unprognostic (1.03e-3)" "unprognostic (2.00e-3)" "unprognostic (6.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (4.48e-2)" "unprognostic (3.09e-3)" "unprognostic (3.80e-2)" "prognostic favourable (9.26e-4)" "prognostic favourable (8.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (4.86e-3)" "unprognostic (1.96e-2)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" 24.7 6.6 6.9 15.3 7.5 8.7 6.3 9.7 9.2 7.8 9.8 17.3 3.9 7.0 9.6 7.0 6.9 18.2 12.4 15.9 6.4 8.8 15.2 8.5 28.6 24.3 9.2 5.8 8.9 6.7 0.6 13.7 8.4 14.5 7.4 12.3 15.3 6.9 6.3 2.5 2.5 12.6 7.9 18.2 45.0 7.2 9.7 5.3 63.0 7.5 2.9 22.6 18.0 4.1 6.1 29.8 2.6 46.4 9.5 7.9 28.3 0.0 0.0 3.4 0.0 0.0 0.6 0.1 1.2 0.1 0.0 0.0 0.0 13.0 2.9 11.5 3.6 0.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.2 0.1 6.2 0.0 0.1 0.0 12.4 0.1 22.1 0.5 0.0 20.5 1.5 10.2 0.0 0.4 0.0 3.2 0.0 3.9 5.8 0.1 0.0 0.1 0.0 0.0 5.8 1.4 0.0 0.1 0.1 0.0 12.6 1.1 0.7 0.1 20.7 0.1 2.6 44.1 2.4 7.9 46.4 6.3 6.1 6.4 7.9 29.8 5.0 7.6 7.8 2.1 9.5 35.2 14.7 3.6 28.3 6.9 7.5 9.7 9.2 6.4 8.8 9.2 5.8 14.5 5.3 ADAM10 "CD156c, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588807-58749978 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" 8200000 "Plasma membrane" "Nucleoplasm, Vesicles" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavourable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 25.9 11.1 15.5 17.1 17.7 15.6 20.0 25.2 17.6 18.6 20.1 15.7 12.7 13.9 19.9 11.8 17.1 13.8 18.0 18.8 17.6 13.7 20.8 14.8 25.0 26.1 23.1 12.4 13.9 13.1 10.9 11.6 36.1 14.5 23.6 16.7 14.6 12.4 19.1 8.9 15.4 15.6 12.8 30.4 40.4 18.4 8.5 18.9 38.5 27.3 9.2 14.9 30.0 19.1 6.2 12.7 26.9 23.7 9.8 12.2 12.8 11.8 26.9 7.3 8.0 9.4 13.6 18.5 10.2 30.4 7.5 10.5 12.4 15.7 5.5 31.6 9.1 24.3 4.4 10.8 10.0 8.2 5.6 9.4 9.8 11.5 10.5 6.6 27.2 11.9 8.0 5.2 7.7 14.6 5.9 15.0 13.2 4.4 21.9 7.6 10.0 3.8 9.1 24.0 14.1 17.5 32.1 8.0 5.2 11.1 12.9 17.6 7.7 13.3 10.3 9.9 11.0 76.0 9.8 8.4 18.1 6.0 13.8 12.9 17.3 12.9 18.8 10.4 8.1 21.5 12.2 5.3 8.0 7.1 12.7 6.2 8.4 7.0 26.9 9.8 23.7 5.8 10.3 12.8 15.5 17.7 25.2 16.9 17.6 13.7 23.1 12.4 14.5 18.9 ADAM17 "CD156B, cSVP, TACE" ENSG00000151694 "ADAM metallopeptidase domain 17" P78536 2 9488486-9555792 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010738, CAB025906, HPA051575" Approved Supported Cytosol "Intracellular and membrane" 27000 Cytosol "CAB025906: , HPA010738: AB_1078100, HPA051575: " "unprognostic (2.28e-1)" "unprognostic (1.29e-3)" "unprognostic (1.28e-1)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (5.15e-2)" "unprognostic (2.12e-3)" "unprognostic (1.55e-1)" "unprognostic (4.09e-2)" "unprognostic (3.69e-1)" "unprognostic (3.53e-3)" "unprognostic (3.13e-1)" "unprognostic (3.82e-3)" "unprognostic (8.63e-2)" "unprognostic (2.61e-1)" "unprognostic (4.48e-2)" "prognostic unfavourable (4.23e-5)" 18.6 11.0 13.6 15.4 13.8 21.9 14.7 20.4 15.5 14.0 11.7 13.8 8.3 8.7 14.2 15.8 18.7 10.7 17.4 13.4 11.2 12.4 12.4 7.8 24.7 15.0 11.6 11.7 18.1 9.6 10.9 11.9 29.0 11.2 8.2 9.4 10.6 12.5 9.8 12.3 16.7 11.1 13.9 14.3 21.4 8.9 17.4 12.3 14.7 12.5 13.9 20.3 12.3 14.4 7.0 7.7 16.0 10.2 6.0 7.9 6.0 7.7 12.7 13.4 13.9 26.5 19.8 24.2 8.1 13.8 9.4 13.9 11.2 18.7 22.1 11.8 10.2 14.2 9.9 17.2 12.9 8.8 9.9 11.3 9.6 9.9 37.5 11.0 12.7 22.1 17.4 15.0 29.1 23.5 15.3 8.5 10.0 7.3 8.3 11.1 11.1 5.2 9.6 13.2 10.5 12.5 12.9 7.9 19.8 9.1 11.1 19.3 5.7 14.2 18.8 16.7 8.7 11.7 15.4 11.1 10.0 19.2 13.8 7.1 19.8 16.0 9.8 7.6 6.1 10.2 7.9 7.0 5.0 5.1 7.7 5.1 4.5 4.6 11.8 6.0 9.5 4.3 5.7 6.0 13.6 13.8 20.4 13.1 11.2 12.4 11.6 11.7 11.2 12.3 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 53.7" "Cell line enhanced" "Detected in many" "SH-SY5Y: 6.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4 "basophil: 2.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" 1301000000 38000000 Vesicles "HPA042014: , HPA042844: , HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 1.4 1.0 3.1 1.4 3.7 0.5 1.4 6.6 4.2 1.4 1.4 1.4 1.4 4.1 1.6 4.0 1.4 2.1 1.5 1.7 3.4 2.2 1.8 53.7 4.8 1.4 2.1 1.4 2.3 1.8 2.2 4.2 1.7 1.6 1.6 1.1 1.6 2.5 2.0 2.6 2.9 4.4 1.4 2.0 1.4 5.5 3.8 1.4 1.4 1.7 1.4 1.4 1.7 1.4 0.3 0.0 2.3 0.0 0.0 0.5 0.1 0.0 1.4 3.4 4.7 2.7 2.5 1.2 1.1 0.9 0.5 0.7 0.5 3.7 0.4 1.5 0.8 0.6 0.3 0.6 0.1 2.0 3.1 0.4 1.4 0.7 2.0 0.1 1.1 6.6 1.7 0.5 1.3 0.3 0.1 1.4 0.5 5.6 0.1 1.5 3.6 2.0 0.4 0.4 1.6 1.5 1.4 2.2 6.9 2.4 1.3 1.8 5.9 0.6 0.8 2.5 1.4 1.6 0.0 2.5 0.6 0.5 2.1 0.4 2.8 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.1 3.7 6.6 4.2 3.4 2.2 2.1 1.4 1.6 1.4 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110851-179345430 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 13.7;ASC TERT1: 13.7;BJ: 12.1;fHDF/TERT166: 14.2;HHSteC: 44.5;HSkMC: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavourable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 24.2 4.3 0.9 5.8 0.7 0.7 29.1 0.9 2.3 16.3 10.1 0.4 3.9 2.7 12.0 9.5 6.0 7.2 9.5 10.1 0.7 1.2 4.2 7.4 13.1 25.9 1.0 1.3 6.3 2.7 1.0 8.7 15.1 2.4 6.0 2.6 3.8 2.5 3.8 3.8 4.6 4.6 13.8 0.7 16.5 4.2 4.3 0.5 0.8 3.2 5.9 1.2 8.8 14.7 1.4 1.3 2.1 0.3 0.8 0.6 0.1 0.0 0.0 0.0 0.3 13.7 13.7 0.0 12.1 2.0 4.6 4.9 0.0 0.0 0.0 0.1 14.2 0.0 0.7 0.0 2.0 0.0 0.6 0.0 0.0 0.9 44.5 0.0 0.0 35.5 0.0 1.2 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.5 0.0 0.0 0.1 0.0 3.9 0.0 7.7 1.2 10.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 1.5 0.3 0.4 0.6 0.2 0.3 0.6 0.5 0.4 1.3 1.4 0.5 0.5 2.1 0.8 0.1 0.8 0.5 0.1 0.9 0.7 0.9 2.3 0.7 1.2 1.0 1.3 2.4 0.5 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184308-161199056 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 58.0" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 10.7;HUVEC TERT2: 12.9;SH-SY5Y: 7.2;TIME: 10.8;U-251 MG: 9.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basal ganglia: 20.7;cerebral cortex: 10.0;midbrain: 28.6;pons and medulla: 20.5;thalamus: 15.7" "Cell type enriched" "Detected in some" 8 "plasmacytoid DC: 8.0" "Lineage enriched" "Detected in many" 8 "dendritic cells: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" "Nuclear speckles" "CAB025876: , HPA051296: , HPA068374: " "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavourable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavourable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 58.0 9.7 2.6 18.1 20.7 1.8 14.6 1.5 10.7 7.8 6.3 33.4 0.0 1.9 5.8 2.0 7.7 14.2 16.4 19.5 3.4 2.3 3.1 11.0 15.7 2.7 28.6 3.5 35.7 10.6 4.7 4.9 4.4 20.5 5.8 3.4 0.0 1.7 1.7 7.7 1.7 3.0 12.0 15.5 1.9 8.1 1.7 15.7 0.0 7.5 1.2 1.4 8.7 4.0 0.5 8.0 1.0 0.2 0.4 0.6 0.2 0.0 0.0 0.2 0.1 6.0 3.8 0.5 4.8 0.2 0.4 2.8 0.1 0.1 0.2 4.1 1.5 0.1 0.0 0.0 1.7 0.1 0.3 0.1 0.4 1.2 0.6 0.0 0.1 4.2 0.0 10.7 0.1 12.9 0.1 0.3 0.3 0.1 0.0 0.2 4.8 0.0 0.1 4.7 0.1 0.0 0.1 0.1 7.2 0.0 0.1 0.1 0.2 0.5 10.8 6.8 0.1 0.3 9.6 0.2 0.1 0.1 2.1 0.1 0.1 0.7 0.2 0.2 0.6 0.1 0.3 0.3 0.3 0.3 0.1 0.5 0.4 0.4 1.0 0.4 0.1 8.0 0.3 0.2 2.6 20.7 1.5 10.0 3.4 2.3 28.6 3.5 20.5 15.7 ADAR "ADAR1, G1P1, IFI4" ENSG00000160710 "Adenosine deaminase, RNA specific" P55265 1 154582062-154627999 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing, RNA-mediated gene silencing" "DNA-binding, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003890, HPA051519, CAB056157" Enhanced Enhanced Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "CAB056157: , HPA003890: AB_1078103, HPA051519: AB_2681520" "unprognostic (3.46e-1)" "unprognostic (8.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.83e-2)" "unprognostic (2.38e-1)" "unprognostic (9.37e-2)" "unprognostic (2.07e-2)" "unprognostic (6.97e-2)" "unprognostic (2.03e-1)" "unprognostic (2.90e-1)" "unprognostic (4.13e-2)" "unprognostic (7.16e-2)" "prognostic unfavourable (7.30e-5)" "unprognostic (3.44e-1)" "unprognostic (1.49e-1)" "unprognostic (9.00e-2)" "unprognostic (3.94e-2)" 36.1 33.1 30.3 36.6 44.4 43.1 29.7 41.4 50.8 30.7 28.2 33.3 19.9 31.4 38.0 26.5 27.7 32.9 28.9 24.0 25.7 38.1 31.5 36.0 34.7 41.3 27.3 32.6 39.2 29.5 46.2 38.4 33.9 39.8 28.8 31.1 32.2 36.7 30.2 14.0 27.0 40.6 36.3 24.4 47.7 29.1 21.9 26.9 57.6 32.8 16.7 41.9 29.7 27.6 7.8 6.1 25.1 8.6 6.4 9.7 5.6 26.1 30.3 26.0 32.0 26.3 27.3 31.0 18.0 36.3 60.5 52.6 26.1 25.8 47.2 29.2 28.8 25.5 33.2 34.3 30.8 45.8 16.7 24.6 21.5 14.8 28.7 34.7 27.3 26.5 25.1 31.0 31.8 31.0 23.2 36.3 21.1 32.0 41.9 17.9 43.0 22.9 40.1 21.4 37.9 20.8 29.2 25.9 30.9 31.2 50.4 37.0 33.9 42.7 28.2 21.8 21.4 17.9 20.9 43.1 47.1 50.7 21.1 22.9 24.5 6.9 6.6 12.0 9.4 8.3 8.8 7.8 9.4 9.7 6.1 6.2 8.8 8.6 25.1 6.4 8.6 5.5 7.1 5.6 30.3 44.4 41.4 50.8 25.7 38.1 27.3 32.6 39.8 26.9 ADARB1 "ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1" ENSG00000197381 "Adenosine deaminase, RNA specific B1" P78563 21 45073853-45226560 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 59.9" "Cell line enhanced" "Detected in many" "HeLa: 27.3;HHSteC: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029645 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA029645: AB_10602106" "unprognostic (2.69e-1)" "unprognostic (7.65e-2)" "prognostic unfavourable (8.16e-5)" "unprognostic (1.82e-2)" "unprognostic (1.07e-2)" "unprognostic (9.07e-2)" "unprognostic (3.29e-2)" "unprognostic (6.97e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-2)" "unprognostic (1.28e-1)" "unprognostic (3.44e-1)" "prognostic unfavourable (3.56e-4)" "unprognostic (4.57e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-2)" "unprognostic (2.38e-2)" 12.2 5.3 7.1 10.4 8.4 4.5 8.9 33.1 11.6 11.7 17.2 2.5 5.6 2.9 13.4 6.6 14.0 8.8 11.1 6.7 7.3 8.1 4.6 4.0 19.9 11.8 7.4 8.1 5.3 4.7 19.0 3.7 12.0 13.6 14.7 5.0 11.0 4.6 8.7 11.8 10.8 5.9 59.9 3.5 10.5 11.7 3.8 4.0 3.9 3.8 4.5 8.4 34.6 20.3 6.1 2.1 4.8 0.6 0.5 2.6 0.5 3.1 0.4 2.4 2.9 3.0 2.1 3.3 2.1 3.5 6.7 4.3 4.9 0.5 1.0 5.7 10.3 0.3 3.6 8.7 7.5 0.7 3.2 6.8 27.3 3.2 31.7 4.6 3.3 11.3 3.8 2.4 7.1 7.1 1.5 0.4 19.6 2.3 3.0 4.4 4.0 4.7 0.9 2.3 3.1 1.5 1.0 14.4 3.8 16.7 0.7 5.3 1.6 3.7 7.4 2.2 2.7 9.0 7.8 3.1 1.4 0.8 2.0 10.9 11.9 1.3 0.2 4.8 1.1 0.6 1.8 2.4 2.6 1.6 0.0 6.1 1.8 1.4 0.2 0.5 0.3 2.1 1.6 0.5 7.1 8.4 33.1 11.6 7.3 8.1 7.4 8.1 13.6 4.0 ADAT1 ENSG00000065457 "Adenosine deaminase, tRNA specific 1" Q9BUB4 16 75596981-75623300 "Enzymes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040713, HPA040903" Approved Supported Nucleoplasm Nucleoplasm "HPA040713: AB_10795371, HPA040903: AB_10794071" "unprognostic (7.71e-3)" "unprognostic (5.35e-2)" "unprognostic (7.62e-2)" "unprognostic (9.00e-2)" "unprognostic (9.99e-2)" "unprognostic (4.69e-2)" "unprognostic (4.54e-2)" "unprognostic (6.65e-3)" "unprognostic (3.38e-1)" "unprognostic (1.14e-2)" "unprognostic (9.75e-2)" "unprognostic (2.97e-1)" "unprognostic (4.60e-3)" "unprognostic (7.21e-2)" "unprognostic (4.92e-1)" "unprognostic (5.58e-3)" "unprognostic (8.27e-2)" 14.8 17.1 12.5 12.6 18.2 13.0 15.1 11.0 23.3 13.5 12.4 21.4 11.8 10.1 15.1 24.4 12.0 12.6 15.8 10.4 17.2 15.1 17.2 17.8 12.8 21.2 16.7 20.5 11.1 15.3 33.5 16.7 14.0 22.3 15.3 15.1 11.8 12.2 14.2 9.0 21.2 13.6 12.6 16.0 21.3 11.7 51.8 16.8 19.4 20.6 9.2 16.7 17.1 11.3 12.5 8.6 15.0 13.0 12.1 20.5 8.3 13.9 23.0 13.8 14.3 20.8 17.1 12.9 15.5 17.8 21.2 16.9 18.9 21.4 16.6 16.5 14.0 16.0 12.7 19.9 21.0 10.9 7.5 7.3 15.9 13.3 15.4 14.2 16.5 18.9 15.7 31.4 25.7 17.7 12.3 7.5 18.6 52.4 16.4 13.4 11.3 9.8 19.5 11.9 20.6 20.6 21.5 19.6 20.2 35.1 11.0 9.6 22.8 9.4 12.9 34.0 14.0 13.6 14.9 15.9 22.3 46.3 14.7 15.1 28.1 9.6 7.2 15.0 14.7 8.4 20.5 12.5 13.8 20.0 8.0 11.8 8.5 12.0 9.5 12.1 13.0 8.6 14.0 8.3 12.5 18.2 11.0 23.3 17.2 15.1 16.7 20.5 22.3 16.8 ADAT2 "DEADC1, dJ20N2.1, TAD2" ENSG00000189007 "Adenosine deaminase, tRNA specific 2" Q7Z6V5 6 143422832-143450673 "Enzymes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035479 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA035479: AB_10611672" "unprognostic (2.24e-1)" "unprognostic (3.07e-3)" "unprognostic (1.55e-1)" "unprognostic (8.20e-2)" "unprognostic (3.05e-2)" "unprognostic (8.58e-2)" "unprognostic (1.07e-3)" "unprognostic (3.31e-2)" "unprognostic (1.34e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-2)" "unprognostic (9.28e-5)" "unprognostic (4.88e-2)" "unprognostic (6.96e-2)" "unprognostic (7.29e-2)" "unprognostic (4.08e-2)" 7.3 9.5 6.6 15.1 9.4 17.1 8.6 7.7 8.8 6.6 9.5 4.9 4.7 9.9 8.3 5.3 12.0 7.9 7.6 4.2 5.2 3.8 7.5 13.2 11.3 17.6 4.9 8.0 7.5 13.3 7.1 9.6 4.0 7.3 8.6 13.3 6.0 10.1 6.2 13.3 17.1 10.0 6.5 6.7 13.1 10.8 4.1 5.3 8.6 10.8 10.1 13.5 6.6 8.7 2.8 3.2 0.4 1.4 1.9 6.6 2.3 2.9 2.5 3.1 10.5 2.6 8.4 4.7 4.1 1.9 2.9 4.0 6.6 7.5 10.4 4.5 2.8 8.5 5.8 5.8 5.7 5.5 12.9 14.7 10.4 13.5 3.3 20.6 7.4 2.8 8.7 5.6 9.0 6.2 16.0 9.0 4.4 4.2 8.0 11.7 3.9 4.7 9.8 9.1 8.5 4.4 3.3 6.9 4.7 3.5 9.4 2.8 4.0 7.6 4.8 4.2 3.6 8.7 8.0 9.3 6.6 7.9 4.0 17.4 4.9 0.0 0.9 0.0 3.2 1.4 4.7 2.8 3.0 2.9 3.2 2.0 3.4 5.1 0.4 1.9 0.2 3.0 6.6 2.3 6.6 9.4 7.7 8.8 5.2 3.8 4.9 8.0 7.3 5.3 ADPRH ARH1 ENSG00000144843 "ADP-ribosylarginine hydrolase" P54922 3 119579268-119589945 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 15.7;HEL: 11.3;HMC-1: 12.7;Karpas-707: 17.3;U-266/70: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001701, HPA036961" Approved Approved "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "CAB001701: , HPA036961: " "prognostic favourable (2.42e-4)" "unprognostic (2.29e-1)" "unprognostic (4.77e-1)" "unprognostic (2.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.65e-1)" "unprognostic (3.06e-2)" "unprognostic (2.63e-1)" "unprognostic (4.24e-2)" "unprognostic (3.31e-3)" "unprognostic (1.88e-1)" "unprognostic (1.71e-1)" "unprognostic (6.04e-2)" "unprognostic (2.60e-3)" "unprognostic (8.87e-2)" "unprognostic (2.03e-1)" "unprognostic (4.35e-2)" 14.3 8.5 2.3 10.9 4.6 2.5 14.8 1.2 2.4 7.1 6.2 4.7 14.6 1.9 7.9 6.2 5.0 5.4 6.6 8.4 2.3 2.4 5.1 5.5 17.4 18.9 3.7 2.7 3.6 11.9 8.1 2.8 23.0 4.0 6.3 3.9 6.8 6.5 14.5 19.7 3.1 6.4 8.8 4.7 13.6 5.1 4.1 3.6 5.3 7.4 5.8 12.0 7.1 6.9 8.2 8.0 13.3 13.0 3.4 9.6 4.9 1.5 2.0 0.4 0.0 1.7 1.9 0.0 1.4 0.3 1.2 1.6 0.6 1.3 0.4 0.6 2.1 0.1 1.4 0.0 1.1 15.7 0.1 11.3 0.2 0.0 2.7 0.0 12.7 2.8 0.0 0.6 0.0 4.9 1.0 17.3 7.4 0.5 0.0 2.7 4.7 3.9 0.0 5.6 0.7 0.7 0.6 0.3 0.0 0.0 0.1 4.2 3.0 7.0 4.0 0.0 0.8 3.1 0.3 16.9 3.7 0.0 2.1 0.0 3.1 7.8 13.0 13.3 0.6 12.0 0.6 8.2 1.4 1.3 8.0 4.9 0.2 0.6 0.4 3.4 9.2 7.0 9.6 4.9 2.3 4.6 1.2 2.4 2.3 2.4 3.7 2.7 4.0 3.6 ADPRHL2 "ARH3, FLJ20446" ENSG00000116863 "ADP-ribosylhydrolase like 2" Q9NX46 1 36088875-36093932 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026641, HPA026739, HPA027104, HPA027141" Approved Enhanced Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA026641: , HPA026739: , HPA027104: AB_10601330, HPA027141: AB_1844619" "unprognostic (3.22e-3)" "unprognostic (5.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.61e-2)" "unprognostic (5.98e-2)" "unprognostic (2.09e-1)" "prognostic unfavourable (2.10e-7)" "unprognostic (3.71e-2)" "unprognostic (2.63e-1)" "unprognostic (5.34e-2)" "unprognostic (3.17e-2)" "unprognostic (7.80e-2)" "prognostic unfavourable (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (9.31e-2)" "unprognostic (3.65e-2)" "unprognostic (4.74e-2)" 15.5 27.6 17.4 15.2 17.4 16.9 20.0 16.5 22.7 15.9 17.3 30.3 17.7 15.6 14.3 17.8 26.3 28.4 13.5 15.1 19.1 18.9 19.8 16.5 20.7 19.1 25.8 18.5 19.7 27.6 15.1 14.0 20.9 19.7 16.6 12.9 12.2 21.9 20.2 26.4 24.4 17.7 22.2 23.5 18.0 14.1 25.1 20.0 21.2 21.2 22.3 19.7 16.1 15.9 27.7 38.9 34.1 38.8 23.5 29.3 29.2 25.2 10.7 12.8 18.0 11.8 8.6 18.3 18.8 15.9 30.5 30.1 12.7 23.0 18.1 18.5 18.8 15.8 16.1 28.9 18.3 12.9 20.2 16.4 13.0 16.9 22.3 18.6 9.8 10.1 22.1 27.6 12.1 19.3 14.1 15.0 14.2 12.2 18.8 28.3 27.5 22.2 15.4 13.5 18.2 27.3 20.8 15.7 24.9 13.8 14.5 30.7 14.9 16.2 13.2 17.7 18.2 24.4 24.9 19.5 18.7 16.0 25.5 18.6 10.8 18.2 32.4 34.1 25.5 38.7 24.0 23.6 27.9 29.3 38.9 27.7 28.3 24.0 31.4 23.5 38.8 24.6 22.8 29.2 17.4 17.4 16.5 22.7 19.1 18.9 25.8 18.5 19.7 20.0 ADPRM "C17orf48, MDS006" ENSG00000170222 "ADP-ribose/CDP-alcohol diphosphatase, manganese dependent" Q3LIE5 17 10697594-10711233 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023265, HPA023820" Approved "HPA023265: AB_1845590, HPA023820: AB_1845591" "unprognostic (7.58e-3)" "prognostic favourable (1.69e-4)" "unprognostic (1.42e-1)" "prognostic favourable (2.38e-5)" "unprognostic (2.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.43e-1)" "unprognostic (6.26e-3)" "unprognostic (2.97e-1)" "unprognostic (6.53e-3)" "unprognostic (2.65e-2)" "unprognostic (1.83e-1)" "unprognostic (4.77e-2)" "unprognostic (5.97e-2)" 11.1 8.2 6.4 9.3 13.1 12.9 13.0 9.8 12.2 10.3 8.1 10.1 16.1 6.6 11.3 9.1 7.8 9.0 7.9 6.4 9.6 6.1 7.8 15.2 6.9 23.2 8.1 5.6 14.2 12.4 4.2 11.9 4.9 9.3 16.7 7.5 8.3 8.8 13.4 14.8 9.2 9.9 6.5 7.3 10.5 12.2 9.5 8.2 18.8 14.6 10.4 11.1 8.8 9.0 10.5 4.2 6.1 3.5 4.0 18.7 5.9 4.1 2.2 4.5 5.3 10.4 13.4 2.2 7.8 8.7 5.7 8.6 1.3 1.9 8.0 4.2 8.2 3.4 1.9 5.6 6.8 5.1 5.3 5.8 3.6 4.4 18.6 3.0 5.4 15.4 10.3 6.0 9.0 10.0 3.9 1.5 8.2 1.1 3.8 5.3 3.7 2.1 3.4 5.2 2.4 10.0 3.0 1.0 6.3 4.1 1.6 9.7 3.8 5.9 10.2 4.0 2.4 4.4 5.2 2.0 1.4 2.3 7.8 4.4 6.7 3.4 3.5 6.1 3.2 3.0 5.4 8.2 8.8 5.8 4.2 10.5 18.7 12.0 2.5 4.0 3.1 2.4 7.7 5.9 6.4 13.1 9.8 12.2 9.6 6.1 8.1 5.6 9.3 8.2 AFMID "DKFZp686F03259, KF" ENSG00000183077 Arylformamidase Q63HM1 17 78187317-78207701 "Enzymes, Predicted intracellular proteins" "Tryptophan catabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 78.7" "Cell line enhanced" "Detected in all" "Hep G2: 61.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 14.5" "Group enriched" "Detected in all" 5 "B-cells: 5.1;dendritic cells: 6.7;monocytes: 14.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023861, HPA026536" Uncertain Approved Mitochondria Mitochondria "HPA023861: AB_1844636, HPA026536: AB_1844637" "unprognostic (3.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.53e-1)" "unprognostic (2.65e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.78e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-3)" "unprognostic (1.53e-2)" "unprognostic (5.78e-2)" "unprognostic (9.59e-3)" "unprognostic (9.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (7.79e-2)" 5.9 3.5 12.1 5.4 17.1 4.6 33.0 27.1 18.3 6.1 7.5 44.8 11.7 8.5 7.5 7.0 7.7 11.3 11.4 9.4 17.3 12.0 39.4 78.7 10.6 5.2 29.7 13.3 15.9 27.7 6.9 4.1 12.4 18.1 10.7 9.2 5.8 24.7 11.8 7.9 15.5 7.1 6.6 27.0 6.2 10.2 6.2 23.9 3.9 6.5 5.6 6.2 6.7 7.4 5.1 6.7 1.7 14.5 1.6 1.1 1.5 6.9 9.9 8.7 7.9 9.8 11.5 4.7 10.0 5.7 7.0 8.5 10.5 5.8 21.8 6.6 7.6 6.0 14.7 8.7 9.9 13.8 11.7 17.5 11.6 61.2 8.6 14.4 9.0 15.4 9.3 8.2 10.7 13.1 17.7 7.6 5.4 6.9 11.0 22.0 7.1 17.0 12.6 8.9 26.0 9.5 6.4 19.3 14.4 8.6 25.9 8.1 7.8 14.0 6.4 10.8 7.1 6.8 7.0 11.7 7.7 22.3 8.9 7.1 2.7 1.1 6.1 0.7 0.7 14.5 1.1 5.1 1.0 1.1 6.7 2.0 0.6 0.6 1.7 1.6 9.3 4.4 0.9 1.5 12.1 17.1 27.1 18.3 17.3 12.0 29.7 13.3 18.1 23.9 AGA ASRG ENSG00000038002 Aspartylglucosaminidase P20933 4 177430770-177442503 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 31.5;Karpas-707: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031415, HPA031417" Enhanced "Intracellular and membrane" 28000000 "HPA031415: AB_10603578, HPA031417: AB_10670967" "unprognostic (8.76e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-3)" "unprognostic (2.11e-3)" "unprognostic (2.70e-2)" "prognostic unfavourable (8.61e-4)" "prognostic unfavourable (1.99e-4)" "unprognostic (3.79e-1)" "unprognostic (6.44e-2)" "unprognostic (4.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.09e-1)" "unprognostic (7.49e-2)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (7.42e-2)" "unprognostic (1.47e-2)" 12.8 15.1 11.2 11.2 11.9 10.9 18.5 4.4 13.7 13.5 12.1 24.2 8.0 8.0 9.8 26.4 18.8 7.1 15.1 8.4 13.0 9.4 20.5 26.5 12.4 12.3 14.0 11.0 10.2 14.7 19.2 9.0 9.3 15.0 10.1 11.1 24.0 27.1 10.8 6.7 16.9 14.4 8.1 22.3 14.9 13.0 13.3 10.0 13.4 14.0 14.3 18.3 9.0 10.2 10.0 11.1 16.3 23.8 8.9 16.3 10.3 2.0 4.6 5.3 7.6 6.3 5.6 3.6 15.5 31.5 8.0 10.2 2.4 10.3 10.3 2.9 11.9 2.5 4.5 5.1 16.3 6.6 2.9 4.3 5.1 6.7 4.1 7.5 3.0 4.0 8.9 5.9 2.7 7.6 3.8 44.6 3.3 5.7 6.0 4.7 2.0 4.8 1.9 2.2 1.5 8.5 5.2 2.9 6.7 4.6 4.0 12.3 9.1 15.4 2.3 5.6 5.0 2.6 5.9 8.6 6.6 5.5 9.0 8.5 6.2 15.0 10.7 16.3 11.7 18.9 13.4 10.0 12.8 14.0 10.5 8.1 11.4 16.3 2.4 8.9 23.8 11.1 12.0 10.3 11.2 11.9 4.4 13.7 13.0 9.4 14.0 11.0 15.0 10.0 AGL ENSG00000162688 "Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase" P35573 1 99850084-99924023 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycogen biosynthesis" "Glycosidase, Glycosyltransferase, Hydrolase, Multifunctional enzyme, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 23.1;skeletal muscle: 85.6;tongue: 34.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028498, HPA054340" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" 16000 Nucleoplasm "Nuclear bodies, Cytosol" "HPA028498: AB_10600975, HPA054340: " "unprognostic (2.90e-1)" "unprognostic (5.34e-2)" "unprognostic (3.99e-3)" "unprognostic (2.18e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "unprognostic (1.12e-1)" "unprognostic (1.92e-2)" "unprognostic (9.37e-3)" "unprognostic (1.11e-1)" "unprognostic (8.10e-3)" "unprognostic (7.61e-2)" "prognostic favourable (1.73e-10)" "unprognostic (6.38e-2)" "unprognostic (2.89e-1)" "unprognostic (1.15e-1)" "unprognostic (7.13e-2)" 5.0 4.5 2.5 4.7 3.6 2.0 4.2 5.4 6.1 3.4 4.5 2.1 5.4 3.3 4.8 4.2 9.1 4.1 2.6 8.2 2.2 2.3 5.8 23.1 4.2 5.3 2.4 4.2 3.8 3.6 8.7 4.7 4.8 2.9 5.5 4.2 3.9 5.1 8.7 85.6 3.7 4.0 5.4 2.8 4.8 4.4 2.9 1.2 7.1 4.3 34.4 3.4 6.7 3.6 3.0 2.3 3.5 1.6 6.1 4.3 2.1 11.8 3.5 4.2 6.9 7.0 6.6 14.2 3.8 5.6 3.3 5.9 13.3 4.0 15.6 7.3 6.4 6.7 24.6 7.4 6.3 8.3 7.8 9.1 12.2 7.4 4.6 8.0 5.5 8.1 4.8 4.6 3.9 5.2 14.9 1.1 3.4 3.7 9.4 2.5 6.7 4.6 0.0 1.4 0.8 10.1 16.1 10.5 7.3 10.9 10.5 5.8 7.5 5.4 5.3 4.0 5.8 5.4 3.7 4.5 3.5 18.1 7.1 2.1 2.1 0.1 1.3 3.5 4.3 1.6 4.1 3.0 3.2 2.9 2.3 2.9 3.2 3.2 1.5 6.1 0.9 2.1 3.3 2.1 2.5 3.6 5.4 6.1 2.2 2.3 2.4 4.2 2.9 1.2 AGMAT FLJ23384 ENSG00000116771 Agmatinase Q9BSE5 1 15572353-15585110 "Enzymes, Predicted intracellular proteins" "Putrescine biosynthesis, Spermidine biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3;kidney: 54.7;liver: 66.1" "Cell line enhanced" "Detected in many" "CACO-2: 18.6;Hep G2: 45.0;RPMI-8226: 11.2" "Group enriched" "Detected in all" 5 "colorectal cancer: 18.5;liver cancer: 25.3;renal cancer: 11.2;stomach cancer: 11.1" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 4.6;T-cells: 10.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA026443, HPA028321" Enhanced 250000 "HPA026443: AB_1844644, HPA028321: AB_10600779" "unprognostic (2.27e-2)" "unprognostic (3.45e-1)" "unprognostic (1.79e-3)" "unprognostic (3.60e-2)" "unprognostic (8.72e-2)" "unprognostic (6.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-2)" "unprognostic (2.06e-2)" "unprognostic (2.37e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-1)" "prognostic favourable (5.13e-4)" "unprognostic (4.43e-3)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (2.45e-2)" 0.7 0.8 0.7 2.8 0.5 0.1 0.4 0.2 1.0 0.2 14.9 0.3 0.0 7.1 0.3 1.2 0.5 0.2 3.6 0.3 0.6 0.8 54.7 66.1 0.2 1.3 0.7 0.3 0.2 1.1 1.3 0.4 0.2 0.6 0.3 2.8 0.1 9.6 0.0 12.3 0.2 21.3 0.1 0.3 1.0 0.5 0.5 0.1 1.0 0.3 1.7 1.5 0.4 0.2 4.6 0.4 1.4 0.3 0.4 10.5 2.8 3.9 3.2 0.2 0.1 0.0 0.4 0.1 0.7 0.7 0.4 0.2 18.6 2.6 0.0 0.1 0.5 0.0 0.0 0.0 0.5 3.8 0.0 2.4 2.6 45.0 0.5 1.9 0.0 0.5 0.2 1.3 0.0 0.4 0.0 5.3 1.0 4.2 0.0 1.8 4.2 1.8 0.0 0.0 11.2 0.1 1.0 0.7 0.5 5.4 0.2 0.6 0.7 3.8 0.4 0.1 0.1 1.0 0.0 0.1 3.0 2.5 0.2 0.0 0.0 0.9 0.3 0.2 2.4 0.3 3.1 4.6 5.7 3.0 0.2 3.2 10.5 5.9 1.4 0.4 0.2 0.4 7.1 2.8 0.7 0.5 0.2 1.0 0.6 0.8 0.7 0.3 0.6 0.1 AGO2 "CASC7, EIF2C2, hAGO2, LINC00980, Q10" ENSG00000123908 "Argonaute 2, RISC catalytic component" Q9UKV8 8 140520156-140635619 "Enzymes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Endonuclease, Hydrolase, Nuclease, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019309, HPA058075" Approved Supported "Nucleoplasm,Cell Junctions" 35000000 "Nucleoplasm, Cell Junctions" "CAB019309: , HPA058075: " "unprognostic (2.75e-2)" "unprognostic (1.79e-3)" "unprognostic (1.27e-1)" "prognostic unfavourable (1.21e-4)" "unprognostic (2.46e-1)" "unprognostic (2.15e-1)" "unprognostic (1.49e-3)" "unprognostic (8.86e-2)" "unprognostic (2.21e-1)" "unprognostic (8.50e-2)" "unprognostic (3.47e-2)" "unprognostic (2.73e-1)" "prognostic unfavourable (1.82e-5)" "unprognostic (1.32e-1)" "unprognostic (2.77e-1)" "unprognostic (1.32e-1)" "unprognostic (3.02e-1)" 11.2 6.6 7.7 9.9 13.1 16.2 25.0 9.9 11.4 7.5 9.2 12.1 12.8 5.3 10.2 10.4 10.6 8.6 8.8 12.4 8.8 5.3 6.9 7.4 13.2 12.5 13.4 5.0 11.8 8.4 13.2 8.8 9.9 10.7 7.5 6.9 5.6 8.1 12.6 37.1 14.1 7.5 15.0 11.7 6.9 10.0 5.9 12.7 11.1 8.6 8.2 8.9 10.4 18.4 2.5 2.1 6.4 2.6 2.4 3.0 1.5 12.6 10.5 10.8 12.3 7.1 8.4 9.1 8.0 5.8 3.6 4.5 11.6 3.8 14.6 10.1 7.7 8.6 18.2 8.6 8.0 8.2 9.5 17.1 18.0 7.4 6.4 7.0 5.8 5.7 7.8 10.0 10.4 8.3 17.8 9.2 11.7 19.2 12.1 5.6 8.0 18.3 12.5 9.1 6.6 4.6 13.2 12.7 9.2 12.5 4.3 8.9 11.0 10.3 11.6 6.3 17.5 9.8 12.8 8.2 2.6 10.3 4.6 12.8 9.2 1.8 2.6 0.7 2.7 2.3 3.0 1.3 2.6 2.3 2.1 2.5 2.7 2.7 6.4 2.4 2.3 1.5 2.1 1.5 7.7 13.1 9.9 11.4 8.8 5.3 13.4 5.0 10.7 12.7 AHCY SAHH ENSG00000101444 Adenosylhomocysteinase P23526 20 34280268-34311802 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA041225, HPA044675" Approved Supported Cytosol 3900000 Cytosol "HPA041225: AB_2677371, HPA044675: AB_2679041" "unprognostic (3.35e-1)" "unprognostic (2.17e-1)" "unprognostic (2.41e-2)" "unprognostic (1.32e-2)" "unprognostic (7.74e-2)" "unprognostic (3.15e-2)" "unprognostic (7.34e-3)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (2.61e-1)" "unprognostic (4.21e-2)" "unprognostic (1.24e-1)" "unprognostic (5.27e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.88e-1)" "unprognostic (2.93e-3)" 15.3 18.6 11.7 15.4 15.0 17.0 24.3 6.3 16.4 25.1 30.0 14.7 18.4 24.6 20.2 23.9 43.4 26.6 22.4 26.0 12.0 12.8 52.2 99.8 19.1 18.1 16.0 10.6 39.1 72.0 15.7 15.0 44.5 13.2 26.9 20.2 14.4 32.4 18.3 48.2 14.8 20.4 18.8 15.7 17.9 22.2 33.3 13.4 25.0 52.8 31.0 29.2 18.2 20.5 9.1 24.1 2.3 26.0 4.6 7.4 11.4 36.8 48.4 20.5 36.2 24.0 25.8 23.6 15.2 21.8 33.9 27.0 130.7 31.9 57.5 27.1 19.4 42.4 48.3 85.2 21.8 7.6 29.3 69.4 24.1 84.1 25.8 32.3 22.8 53.4 38.8 21.0 33.9 23.1 33.7 14.6 17.9 39.1 42.2 30.6 26.3 47.2 31.7 52.2 40.4 30.3 26.3 35.6 23.7 30.3 36.0 50.4 54.1 30.1 14.6 29.5 31.4 14.8 28.6 21.8 31.9 34.6 21.7 20.0 15.7 2.3 13.7 0.4 4.1 26.0 6.7 9.1 6.0 5.3 21.1 7.8 6.6 7.4 1.1 4.6 16.5 24.1 6.7 11.4 11.7 15.0 6.3 16.4 12.0 12.8 16.0 10.6 13.2 13.4 AHCYL2 KIAA0828 ENSG00000158467 "Adenosylhomocysteinase like 2" Q96HN2 7 129225023-129430211 "Enzymes, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 72.4" "Cell line enriched" "Detected in all" 8 "HDLM-2: 71.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053128 Uncertain Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA053128: AB_2682050" "unprognostic (1.57e-1)" "unprognostic (2.91e-1)" "unprognostic (8.52e-3)" "unprognostic (1.71e-3)" "unprognostic (7.44e-3)" "prognostic favourable (4.17e-4)" "unprognostic (8.85e-2)" "unprognostic (1.43e-1)" "unprognostic (3.35e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-1)" "unprognostic (6.79e-3)" "prognostic favourable (1.08e-7)" "unprognostic (4.70e-3)" "unprognostic (2.46e-1)" "unprognostic (7.21e-2)" "unprognostic (2.62e-1)" 4.3 6.6 12.8 5.9 20.3 1.5 4.3 7.2 16.9 7.1 61.8 13.3 5.1 23.1 6.1 3.3 5.7 4.4 22.7 3.4 16.5 9.6 11.9 3.4 26.1 4.2 10.7 14.9 5.7 5.8 9.1 12.8 5.1 19.8 5.0 72.4 24.3 15.0 3.3 20.7 9.8 15.0 5.3 11.4 2.9 16.5 8.1 9.6 4.6 24.1 4.0 4.0 5.4 4.7 0.9 1.3 2.0 2.5 3.3 5.0 0.5 2.6 4.2 8.1 4.8 2.2 3.2 1.7 2.1 2.9 2.4 2.1 2.4 1.8 1.6 2.2 2.3 1.8 4.0 3.3 2.7 71.8 5.0 3.8 4.6 1.9 1.3 2.8 4.9 3.0 4.3 1.9 2.9 4.7 1.7 9.1 3.1 2.5 4.1 3.6 4.0 3.0 2.7 2.2 4.3 4.8 3.5 3.7 2.3 4.8 2.0 2.8 1.9 2.0 2.7 2.0 1.2 5.4 2.2 3.8 4.3 2.2 5.3 3.0 3.1 0.1 1.2 2.0 0.9 2.5 1.2 0.9 1.5 0.7 1.3 0.5 1.3 0.5 0.4 3.3 1.2 0.4 5.0 0.5 12.8 20.3 7.2 16.9 16.5 9.6 10.7 14.9 19.8 9.6 AICDA "AID, ARP2, CDA2, HIGM2" ENSG00000111732 "Activation induced cytidine deaminase" Q9GZX7 12 8602166-8612871 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 6.6;lymphoid tissue: 22.3" "Group enriched" "Detected in some" 6 "Daudi: 48.4;U-698: 40.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 6.6" "Group enriched" "Detected in many" 6 "B-cells: 6.6;granulocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "unprognostic (2.71e-2)" "unprognostic (1.39e-2)" "unprognostic (7.76e-2)" "unprognostic (1.68e-1)" "unprognostic (8.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.05e-2)" "unprognostic (9.69e-2)" "unprognostic (1.96e-2)" "unprognostic (4.04e-6)" "unprognostic (8.82e-2)" "unprognostic (1.28e-1)" "unprognostic (4.21e-1)" "unprognostic (4.65e-1)" 1.3 0.1 0.1 22.3 0.1 0.4 0.4 0.1 0.1 0.2 0.3 0.1 0.1 0.0 0.9 0.1 0.1 0.2 0.3 0.4 0.1 0.0 0.2 0.1 0.5 15.5 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.1 1.8 0.1 1.1 0.5 3.9 0.1 0.1 1.7 0.2 0.2 0.1 0.6 0.3 0.1 12.2 0.1 0.7 6.6 0.7 1.6 0.7 0.5 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 48.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.6 7.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 40.4 0.0 0.1 0.0 1.0 0.7 0.4 0.4 0.3 0.2 4.3 0.4 0.2 0.4 6.6 0.4 0.4 1.6 0.5 0.4 0.7 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 ALG13 "CDG1S, CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W" ENSG00000101901 "ALG13, UDP-N-acetylglucosaminyltransferase subunit" Q9NP73 X 111665811-111760649 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Glycosyltransferase, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002853 Approved "HPA002853: AB_1078131" "unprognostic (4.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (6.97e-2)" "unprognostic (6.14e-2)" "unprognostic (2.74e-1)" "unprognostic (6.55e-3)" "unprognostic (2.26e-2)" "unprognostic (3.39e-3)" "unprognostic (1.73e-2)" "unprognostic (4.62e-3)" "prognostic unfavourable (1.10e-6)" "unprognostic (1.19e-1)" "unprognostic (1.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.45e-2)" 20.6 23.0 18.4 23.2 23.2 19.3 24.8 20.9 25.5 21.1 23.3 21.6 22.0 18.0 26.3 28.5 18.3 22.5 22.2 16.8 16.6 16.2 23.5 31.1 19.7 28.4 22.4 16.1 24.2 18.8 13.0 41.7 18.7 19.5 26.7 26.5 16.3 19.5 25.6 11.2 25.2 25.7 23.5 21.6 31.4 20.1 19.0 20.3 23.6 24.5 14.6 25.8 18.3 20.9 10.2 14.4 21.7 12.5 3.4 11.1 7.1 11.5 13.1 11.8 7.5 7.7 11.0 6.7 9.5 9.8 12.2 15.1 13.2 12.2 10.1 18.2 13.1 6.7 14.0 6.6 12.9 7.2 9.4 5.5 14.9 14.9 11.4 10.1 22.3 13.1 12.5 9.8 21.2 13.2 12.3 29.1 12.1 29.5 8.5 9.1 10.8 18.1 6.6 7.5 14.0 19.5 18.0 7.1 10.5 13.5 8.2 8.2 7.3 9.7 8.9 10.6 5.3 13.6 18.1 14.0 23.2 16.2 11.3 13.4 8.0 21.7 12.4 12.2 7.8 12.5 7.6 8.4 8.9 7.6 14.4 10.2 11.1 9.1 2.5 3.4 9.4 7.5 10.7 7.1 18.4 23.2 20.9 25.5 16.6 16.2 22.4 16.1 19.5 20.3 ALPI ENSG00000163295 "Alkaline phosphatase, intestinal" P09923 2 232456123-232460032 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 406 "intestine: 133.2" "Cell line enriched" "Detected in some" 12 "CACO-2: 12.4" "Cancer enhanced" "Detected in many" "liver cancer: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" "Plasma membrane" "HPA038764: , HPA038765: , HPA051699: " "unprognostic (1.01e-1)" "unprognostic (7.71e-2)" "unprognostic (4.14e-2)" "unprognostic (1.47e-1)" "unprognostic (9.57e-4)" "unprognostic (8.07e-2)" "unprognostic (1.71e-1)" "unprognostic (9.99e-2)" 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 63.0 0.0 0.0 57.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.0 0.1 0.1 133.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 ALPL "HOPS, TNSALP" ENSG00000162551 "Alkaline phosphatase, liver/bone/kidney" P05186 1 21509372-21578412 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 73.3;liver: 52.7;lung: 45.1" "Cell line enhanced" "Detected in some" "HSkMC: 52.2;hTEC/SVTERT24-B: 40.8;LHCN-M2: 29.7;SCLC-21H: 26.0" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 91 "neutrophil: 73.3" "Lineage enriched" "Detected in single" 127 "granulocytes: 73.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" 7300000 Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavourable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavourable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" 15.9 22.7 4.5 17.6 6.0 2.6 10.6 2.2 7.8 2.2 2.1 4.1 0.7 1.9 3.7 1.1 2.0 5.7 2.8 10.9 5.7 4.2 29.7 52.7 45.1 28.1 5.3 4.8 1.2 4.3 2.4 4.1 2.2 7.7 2.6 1.3 18.3 3.1 6.6 0.9 1.8 2.7 2.5 3.8 19.6 1.8 2.9 2.7 0.5 3.7 1.7 3.9 7.1 8.4 0.5 0.0 73.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 1.9 3.3 0.1 0.7 0.2 0.4 0.2 0.0 0.6 2.2 0.0 0.0 8.9 0.0 0.1 0.0 0.6 0.0 1.1 1.0 0.5 0.0 0.2 52.2 0.0 40.8 0.1 0.0 0.0 0.0 29.7 0.0 0.0 0.0 11.9 0.0 0.0 1.1 0.0 0.0 0.0 26.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 73.3 0.0 0.0 0.0 0.0 0.0 4.5 6.0 2.2 7.8 5.7 4.2 5.3 4.8 7.7 2.7 ALPP ENSG00000163283 "Alkaline phosphatase, placental" P05187 2 232378534-232382889 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "placenta: 240.2" "Group enriched" "Detected in some" 6 "HaCaT: 86.1;SiHa: 23.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "CAB026327, HPA038764, HPA038765, HPA051699" Enhanced Approved "Plasma membrane" "Intracellular and membrane" "Plasma membrane" "CAB026327: , HPA038764: , HPA038765: , HPA051699: " "unprognostic (4.86e-2)" "unprognostic (5.19e-3)" "unprognostic (6.67e-3)" "unprognostic (2.60e-1)" "unprognostic (2.44e-3)" "unprognostic (1.26e-2)" "prognostic unfavourable (4.33e-4)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 14.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 240.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.5 1.6 0.5 1.1 0.5 0.3 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 9.7 0.0 0.0 0.0 86.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 23.7 8.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.7 0.5 0.2 0.5 0.3 0.3 0.3 0.1 1.0 0.4 0.4 1.6 1.1 0.5 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALPPL2 ENSG00000163286 "Alkaline phosphatase, placental like 2" P10696 2 232406843-232410714 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.2;lung: 9.4" "Group enriched" "Detected in some" 4 "CAPAN-2: 24.5;HaCaT: 18.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 49.1;testis cancer: 64.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020698, HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" "Plasma membrane" "CAB020698: , HPA038764: , HPA038765: , HPA051699: " "unprognostic (1.39e-1)" "unprognostic (6.63e-3)" "unprognostic (1.27e-2)" "unprognostic (2.89e-1)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.69e-3)" "unprognostic (1.65e-1)" "unprognostic (2.67e-1)" "unprognostic (6.72e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.0 0.0 0.0 0.2 1.5 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.6 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.5 24.5 0.0 0.0 0.0 18.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943293-95968716 "Enzymes, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 99.0" "Cell line enhanced" "Detected in many" "A-431: 19.1;HMC-1: 21.1;Karpas-707: 26.1;SiHa: 17.5;SK-BR-3: 19.6;U-266/70: 21.1;U-266/84: 24.7" "Cancer enriched" "Detected in many" 14 "liver cancer: 23.4" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" 410000 Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: AB_10672967, HPA040149: " "unprognostic (4.81e-2)" "unprognostic (2.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (1.80e-2)" "unprognostic (2.88e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (3.35e-3)" "unprognostic (1.17e-1)" "unprognostic (4.63e-3)" "unprognostic (3.98e-2)" "unprognostic (1.70e-1)" "unprognostic (4.08e-3)" "unprognostic (2.61e-1)" 1.1 5.7 0.5 2.4 0.8 2.0 0.9 0.5 1.3 0.7 0.7 0.6 0.4 1.9 0.9 0.5 0.8 0.5 0.7 1.1 0.6 0.5 4.4 99.0 1.3 1.4 0.5 0.4 0.7 1.1 0.0 1.2 0.6 1.0 0.7 0.0 0.8 1.3 0.7 11.3 2.2 1.9 0.6 0.6 2.9 1.9 6.2 0.5 0.7 0.6 0.7 0.7 0.8 0.9 1.5 1.2 3.7 3.8 5.7 1.6 1.4 19.1 4.2 0.3 2.8 0.1 0.0 4.3 0.6 0.2 0.3 0.6 1.9 2.5 1.7 1.9 0.0 3.6 0.1 0.0 0.1 6.6 0.7 1.8 2.9 3.7 0.0 2.5 21.1 0.0 0.1 0.3 0.0 0.1 1.3 26.1 0.0 2.9 1.6 4.7 2.0 1.0 3.5 0.1 2.1 0.0 1.8 2.2 3.1 17.5 19.6 2.2 2.0 3.6 0.0 2.7 9.5 3.4 2.4 21.1 24.7 2.6 1.9 5.1 3.1 0.3 1.6 3.7 1.2 1.4 1.1 1.5 0.6 1.6 1.2 1.0 1.0 1.1 1.2 5.7 3.8 0.6 0.3 1.4 0.5 0.8 0.5 0.6 0.6 0.5 0.5 0.4 1.0 0.5 AMDHD2 CGI-14 ENSG00000162066 "Amidohydrolase domain containing 2" Q9Y303 16 2520357-2531422 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA041184, HPA041321" Enhanced Approved Nucleoli,Cytosol 69000 "Nucleoli, Cytosol" "HPA041184: AB_10803998, HPA041321: AB_10795588" "unprognostic (1.20e-1)" "prognostic favourable (5.19e-4)" "unprognostic (7.86e-3)" "unprognostic (2.39e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.48e-2)" "unprognostic (2.14e-1)" "unprognostic (3.28e-1)" "unprognostic (1.66e-1)" "unprognostic (1.88e-2)" "unprognostic (8.68e-2)" "unprognostic (1.30e-1)" "unprognostic (8.37e-2)" "unprognostic (4.71e-2)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" 12.8 16.9 8.6 11.4 10.1 12.7 10.9 7.3 16.0 9.4 8.8 11.1 11.3 19.5 10.4 11.9 8.4 9.0 14.6 11.8 7.1 4.8 15.3 10.5 20.0 15.8 9.8 11.3 8.1 10.1 6.5 7.5 10.7 8.9 8.6 2.4 10.9 16.1 9.6 10.2 15.0 19.1 7.2 8.3 22.2 11.5 25.7 7.9 7.3 9.9 11.0 8.9 9.3 8.0 9.8 17.1 16.6 15.8 4.9 8.1 4.8 6.4 8.8 1.9 4.0 2.1 1.7 14.3 5.9 2.5 4.7 5.9 6.3 11.6 3.0 4.2 1.1 5.9 1.1 1.6 0.1 3.8 5.3 4.3 7.9 8.2 8.0 3.1 14.1 4.0 1.7 3.4 0.5 2.9 9.8 7.2 1.9 15.6 5.0 8.6 4.1 6.8 19.7 3.0 11.0 1.3 3.6 7.3 7.2 3.8 9.2 15.5 9.5 0.8 4.0 5.3 8.1 10.5 3.0 15.2 9.7 5.9 5.9 5.9 6.6 9.9 6.1 16.5 7.4 15.8 5.5 9.8 5.9 5.3 2.3 7.4 5.0 4.2 16.6 4.9 15.2 17.1 8.1 4.8 8.6 10.1 7.3 16.0 7.1 4.8 9.8 11.3 8.9 7.9 AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 212.4" "Cell line enriched" "Detected in single" 32 "U-266/70: 13.9" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 31 "memory B-cell: 3.0" "Lineage enriched" "Detected in single" 31 "B-cells: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA026478, HPA028080" Enhanced "Intracellular and membrane" "HPA026478: AB_10599969, HPA028080: AB_10600776" "unprognostic (1.98e-3)" "unprognostic (1.43e-3)" "unprognostic (8.75e-3)" "unprognostic (8.03e-2)" "unprognostic (1.95e-2)" "unprognostic (5.61e-3)" "unprognostic (8.21e-2)" "unprognostic (4.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.36e-5)" "unprognostic (1.68e-1)" "unprognostic (3.70e-1)" "unprognostic (3.36e-1)" "unprognostic (4.02e-1)" 2.9 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.2 3.3 0.0 0.0 3.5 0.1 3.3 1.4 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.6 1.2 0.0 2.1 1.5 212.4 0.1 1.4 0.0 0.1 0.5 0.7 0.1 0.0 0.0 0.2 25.3 2.8 0.2 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 AMPD2 SPG63 ENSG00000116337 "Adenosine monophosphate deaminase 2" Q01433 1 109616104-109632051 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 64.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.8;granulocytes: 29.7;monocytes: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027137, HPA045760, HPA050590" Approved Enhanced Cytosol 380000 Cytosol "HPA027137: , HPA045760: , HPA050590: " "unprognostic (2.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.50e-1)" "unprognostic (1.43e-3)" "unprognostic (9.01e-2)" "unprognostic (5.25e-2)" "unprognostic (3.91e-3)" "unprognostic (1.71e-1)" "unprognostic (4.02e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-3)" "unprognostic (1.50e-1)" "prognostic unfavourable (3.78e-10)" "unprognostic (9.16e-2)" "unprognostic (2.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" 8.1 22.7 20.2 21.7 41.3 64.4 4.9 16.3 26.8 9.5 10.1 9.5 6.3 17.1 9.0 6.0 5.9 11.8 13.2 5.2 21.7 19.4 7.8 13.0 8.2 10.7 14.2 14.2 16.3 9.4 13.0 37.1 10.8 18.3 9.7 5.7 15.7 9.1 12.2 2.1 10.0 11.6 9.1 8.5 15.9 8.3 5.3 12.2 10.3 6.4 3.0 7.5 8.2 8.1 2.8 8.8 29.7 24.5 3.0 4.3 5.4 10.9 12.8 18.8 15.8 16.4 16.4 7.1 15.6 32.0 16.0 15.8 9.7 4.7 5.4 12.0 29.3 8.6 9.8 14.5 9.9 8.8 13.3 28.6 16.8 10.8 15.4 12.1 30.8 18.3 7.7 21.2 16.5 13.8 8.8 14.8 11.4 17.0 17.9 29.0 12.1 13.6 12.8 7.2 8.4 14.7 6.7 14.6 15.3 10.7 13.0 12.7 7.3 11.3 13.2 19.8 23.0 24.2 16.1 29.6 14.3 7.8 29.5 18.9 20.6 0.5 9.2 11.2 3.4 19.6 4.3 2.8 3.3 3.4 8.8 1.7 3.8 2.8 29.7 3.0 24.5 1.4 2.6 5.4 20.2 41.3 16.3 26.8 21.7 19.4 14.2 14.2 18.3 12.2 AMPD3 ENSG00000133805 "Adenosine monophosphate deaminase 3" Q01432 11 10308313-10507579 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.2;skeletal muscle: 61.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.3;CAPAN-2: 19.0;HMC-1: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038662, HPA047408" Uncertain Enhanced "Nuclear membrane" "Nuclear membrane" "HPA038662: , HPA047408: " "unprognostic (2.24e-1)" "unprognostic (3.88e-3)" "unprognostic (1.44e-2)" "prognostic favourable (2.37e-4)" "unprognostic (1.89e-2)" "unprognostic (1.71e-3)" "unprognostic (2.91e-3)" "unprognostic (1.25e-1)" "unprognostic (7.83e-2)" "unprognostic (2.26e-1)" "unprognostic (1.84e-2)" "unprognostic (4.68e-1)" "unprognostic (3.06e-2)" "unprognostic (7.07e-2)" "unprognostic (4.42e-2)" "unprognostic (2.98e-1)" "unprognostic (2.12e-2)" 2.9 13.7 5.3 13.8 14.0 39.2 2.3 2.3 7.8 3.3 3.4 19.6 0.7 4.7 3.1 4.2 5.2 8.0 4.6 2.1 7.4 7.1 4.2 1.5 4.5 12.7 15.2 5.7 2.3 2.5 24.9 14.5 3.7 11.2 5.5 4.9 4.3 4.7 2.8 61.0 10.8 5.0 3.1 12.8 8.3 4.6 1.4 12.6 14.8 2.7 7.6 14.2 6.1 5.1 7.6 3.9 17.0 6.0 3.3 5.3 2.3 7.4 1.1 0.3 0.1 4.0 2.9 0.4 6.8 24.3 1.7 1.7 3.7 19.0 2.7 0.6 3.1 4.7 0.1 6.4 5.0 6.7 0.2 6.7 0.9 0.5 1.3 9.1 20.2 10.6 10.0 3.3 4.3 0.7 10.1 2.9 5.5 0.2 5.3 11.9 0.9 6.7 2.0 8.8 9.8 0.3 6.3 2.8 1.5 1.5 0.2 0.4 0.2 3.1 1.8 7.7 0.1 5.3 0.2 2.7 1.5 2.9 8.9 9.1 0.2 6.6 6.0 17.0 2.3 3.8 5.3 7.6 3.3 2.5 3.9 5.8 3.7 2.5 8.3 3.3 1.6 2.5 1.9 2.3 5.3 14.0 2.3 7.8 7.4 7.1 15.2 5.7 11.2 12.6 AMY1A AMY1 ENSG00000237763 "Amylase, alpha 1A (salivary)" P04745 1 103655290-103664554 "Enzymes, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 100 "salivary gland: 654.0" "Cell line enhanced" "Detected in some" "NTERA-2: 1.3;SH-SY5Y: 2.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "CAB004310, HPA045394, HPA045399, HPA046980" Enhanced "Secreted to digestive system" 68000000 "CAB004310: AB_626668, HPA045394: , HPA045399: , HPA046980: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 654.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.3 0.3 0.6 0.0 1.1 0.7 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.1 0.6 0.0 0.1 1.1 0.1 0.3 0.1 0.0 0.7 0.2 0.0 0.5 0.0 0.1 0.7 AMY1B AMY1 ENSG00000174876 "Amylase, alpha 1B (salivary)" P04745 1 103687415-103696680 "Enzymes, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "salivary gland: 302.4" "Cell line enhanced" "Detected in some" "NTERA-2: 1.2;SH-SY5Y: 2.1;U-266/70: 1.8" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" 68000000 "HPA045394: , HPA045399: , HPA046980: " "unprognostic (7.34e-2)" "unprognostic (2.59e-1)" "unprognostic (6.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.96e-1)" 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 6.5 0.2 0.2 0.2 0.0 0.2 0.2 0.2 4.0 0.2 0.2 0.2 0.0 0.2 0.2 0.7 0.2 0.2 0.2 0.2 23.0 0.0 0.2 0.2 0.2 0.2 0.0 0.2 302.4 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.2 1.1 0.2 0.2 0.2 0.2 0.1 0.3 0.3 0.6 0.0 1.1 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.4 1.2 0.0 0.7 0.1 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.6 0.0 0.1 1.1 0.1 0.3 0.1 0.0 0.7 0.2 0.0 0.5 0.0 0.1 0.7 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 AMY1C AMY1 ENSG00000187733 "Amylase, alpha 1C (salivary)" P04745 1 103750406-103758690 "Enzymes, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 34.3;salivary gland: 62.5" "Cell line enriched" "Detected in single" 4 "THP-1: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" 68000000 "HPA045394: , HPA045399: , HPA046980: " 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 62.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 9.6 4.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 AMY2A AMY2 ENSG00000243480 "Amylase, alpha 2A (pancreatic)" P04746 1 103616811-103625780 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "pancreas: 1849.4" "Cell line enhanced" "Detected in some" "THP-1: 1.0;U-2 OS: 1.2" "Cancer enriched" "Detected in single" 2010 "pancreatic cancer: 200.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045394, HPA045399, CAB045960, HPA046980" Enhanced "Secreted to digestive system" 77000000 "CAB045960: AB_2226891, HPA045394: , HPA045399: , HPA046980: " "unprognostic (3.27e-1)" "unprognostic (1.78e-3)" "unprognostic (3.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.13e-2)" 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.9 1849.4 0.0 0.2 0.2 0.2 0.2 0.0 0.2 59.9 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.3 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 AMY2B AMY2 ENSG00000240038 "Amylase, alpha 2B (pancreatic)" P19961 1 103553815-103579534 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pancreas: 939.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 11.3;EFO-21: 11.6" "Cancer enriched" "Detected in many" 15 "pancreatic cancer: 25.1" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "classical monocyte: 8.5" "Low lineage specificity" "Detected in many" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" 75000000 "HPA045394: , HPA045399: , HPA046980: " "unprognostic (8.69e-4)" "unprognostic (3.71e-3)" "unprognostic (6.41e-2)" "unprognostic (9.75e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-4)" "unprognostic (1.21e-2)" "unprognostic (1.63e-2)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (7.41e-3)" "unprognostic (1.55e-2)" "unprognostic (5.74e-2)" "unprognostic (4.22e-1)" "unprognostic (3.12e-4)" 1.7 0.5 0.8 0.8 1.5 0.4 1.0 2.6 0.8 0.9 0.9 0.8 0.8 0.5 0.8 1.0 0.8 1.5 0.9 1.1 0.8 0.5 1.5 1.1 1.0 1.1 1.0 0.9 1.2 939.9 0.8 1.1 0.8 0.8 0.9 0.4 0.9 145.7 1.0 1.7 1.3 0.9 0.8 0.8 1.0 0.4 0.8 0.8 0.8 2.4 1.1 0.8 0.8 0.8 1.8 2.6 1.9 8.5 0.1 1.1 1.9 0.0 0.6 1.2 0.0 6.3 11.3 1.2 0.9 0.9 0.7 1.7 0.0 0.2 1.1 11.6 0.3 1.3 0.1 1.4 1.6 1.4 1.7 2.0 4.3 0.8 0.9 2.6 2.8 7.7 7.5 0.8 1.3 0.2 0.0 3.4 0.9 0.0 2.0 0.5 0.1 1.6 0.6 0.0 5.0 6.5 2.1 3.1 0.5 2.6 1.2 0.8 0.1 1.5 0.9 0.4 1.0 0.5 0.7 3.9 0.1 0.3 2.1 1.9 0.2 0.0 8.5 1.7 0.8 3.9 0.6 1.7 0.3 0.4 2.6 1.8 1.1 0.4 1.9 0.1 3.6 0.8 0.3 1.9 0.8 1.5 2.6 0.8 0.8 0.5 1.0 0.9 0.8 0.8 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784889-89815401 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 195.3;kidney: 78.7;pancreas: 93.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 77.0;BJ: 76.7;BJ hTERT+: 109.7;HMC-1: 69.8;HSkMC: 67.4;HUVEC TERT2: 85.8;TIME: 85.8;U-2197: 93.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in many" 5 "neutrophil: 59.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 59.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" 1500000000 "Plasma membrane" "CAB002417: AB_563491, HPA004625: " "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 21.3 1.1 0.6 2.9 0.8 9.5 17.0 1.0 1.3 8.2 21.2 0.8 0.5 195.3 1.4 8.4 3.6 1.4 27.7 3.7 0.4 0.3 78.7 37.7 9.7 9.3 0.9 0.9 1.8 93.9 0.0 0.7 14.7 1.3 8.6 4.7 4.0 6.6 1.8 1.6 4.9 155.8 4.3 1.2 7.2 0.8 4.7 0.2 5.6 1.5 4.2 3.8 4.7 3.0 0.0 6.9 59.4 12.8 0.0 0.0 5.5 0.0 4.9 0.0 0.0 60.1 77.0 0.5 76.7 109.7 9.4 8.3 0.5 0.0 0.0 0.9 65.8 0.0 0.5 0.0 3.7 0.0 0.0 14.5 0.4 11.4 35.4 1.0 69.8 67.4 0.1 29.7 0.0 85.8 0.4 0.1 3.6 0.0 0.0 34.1 0.2 5.2 0.0 0.0 0.8 42.9 0.0 0.1 0.7 0.0 0.1 0.0 0.0 6.7 85.8 41.4 0.0 93.5 0.0 0.0 0.0 0.0 0.1 0.0 2.2 5.7 12.8 10.4 0.0 7.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 59.4 0.0 12.0 0.1 0.0 5.5 0.6 0.8 1.0 1.3 0.4 0.3 0.9 0.9 1.3 0.2 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512949-36724549 "Enzymes, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 54.6;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 5 "NB-4: 20.9;THP-1: 16.0;U-937: 7.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 54.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021666, HPA026716" Approved "Secreted to blood" "HPA021666: , HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 8.4 3.4 5.2 17.2 4.9 19.3 2.8 1.9 3.6 3.1 5.3 7.4 0.2 4.9 3.9 7.2 2.5 3.1 8.4 3.4 4.8 3.8 3.1 6.8 9.4 23.2 6.9 2.0 2.1 2.3 0.6 2.4 5.7 5.8 3.8 7.3 3.8 4.5 1.4 1.5 1.6 7.6 4.7 12.6 57.4 3.3 1.4 6.8 14.0 2.9 0.4 10.9 7.2 2.8 0.3 34.8 18.7 54.6 19.2 8.8 31.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.9 0.0 0.3 0.1 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 20.9 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 7.0 0.0 0.3 54.6 17.6 8.8 47.9 1.8 0.3 0.4 6.1 34.8 0.0 1.0 7.8 18.7 19.2 20.2 0.5 0.1 31.0 5.2 4.9 1.9 3.6 4.8 3.8 6.9 2.0 5.8 6.8 APEH "D3F15S2, D3S48E, DNF15S2" ENSG00000164062 "Acylaminoacyl-peptide hydrolase" P13798 3 49674002-49683963 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029700, HPA029701, HPA029702, HPA029703" Enhanced Enhanced Cytosol 1600000 Cytosol "HPA029700: AB_10599278, HPA029701: AB_10600333, HPA029702: AB_10602411, HPA029703: AB_10601348" "unprognostic (4.93e-2)" "unprognostic (5.42e-2)" "unprognostic (6.04e-3)" "unprognostic (2.71e-1)" "unprognostic (9.32e-2)" "unprognostic (8.20e-2)" "unprognostic (3.65e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (8.03e-2)" "unprognostic (3.21e-1)" "unprognostic (4.30e-2)" "prognostic favourable (3.32e-10)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.34e-2)" "unprognostic (7.67e-2)" 12.3 31.4 14.3 16.9 18.4 17.3 13.5 14.2 28.2 13.4 23.5 14.4 25.3 24.2 14.1 19.0 23.8 17.2 19.1 23.1 14.2 14.2 33.6 36.9 15.0 23.9 13.9 20.0 13.9 22.7 33.5 26.6 18.6 16.3 16.1 26.6 19.5 19.8 19.8 55.1 16.9 21.7 14.1 9.8 19.2 21.9 22.3 11.7 22.6 26.6 26.6 20.7 19.9 13.7 20.5 26.2 30.4 27.9 21.8 29.5 28.1 25.4 20.8 22.8 29.6 19.9 13.4 30.2 16.6 21.4 23.4 25.1 33.4 27.6 32.6 18.7 18.9 23.6 25.4 38.5 17.8 15.5 10.5 35.1 34.7 27.3 19.8 37.6 54.7 15.2 29.2 13.4 27.8 21.1 21.7 16.2 23.2 23.5 26.5 19.1 13.5 19.0 10.1 19.6 42.3 46.3 60.4 10.9 18.9 18.8 45.7 20.7 30.1 20.1 9.6 14.5 25.4 22.6 22.4 18.6 13.2 19.4 25.0 26.6 20.8 30.2 25.5 30.4 28.5 27.9 22.5 20.5 23.5 26.7 26.2 17.4 24.9 24.2 8.0 21.8 26.7 21.0 29.5 28.1 14.3 18.4 14.2 28.2 14.2 14.2 13.9 20.0 16.3 11.7 APOBEC1 "APOBEC-1, BEDP, CDAR1, HEPR" ENSG00000111701 "Apolipoprotein B mRNA editing enzyme catalytic subunit 1" P41238 12 7649400-7665903 "Enzymes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "intestine: 56.1" "Cell line enriched" "Detected in single" 20 "CAPAN-2: 7.7" "Group enriched" "Detected in some" 9 "colorectal cancer: 6.2;pancreatic cancer: 6.1;stomach cancer: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "unprognostic (2.35e-1)" "unprognostic (3.80e-4)" "unprognostic (7.96e-3)" "unprognostic (1.79e-1)" "unprognostic (4.38e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 23.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 56.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APOBEC2 "ARCD1, ARP1" ENSG00000124701 "Apolipoprotein B mRNA editing enzyme catalytic subunit 2" Q9Y235 6 41053304-41064511 "Enzymes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "heart muscle: 58.4;skeletal muscle: 163.0;tongue: 53.9" "Cell line enhanced" "Detected in some" "BEWO: 2.2;CACO-2: 8.9;HSkMC: 3.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 4.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014252, HPA017957" Enhanced "HPA014252: AB_1844932, HPA017957: AB_1844933" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-1)" "unprognostic (2.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (7.22e-2)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-1)" "unprognostic (2.01e-2)" "unprognostic (7.02e-2)" "unprognostic (3.69e-1)" "unprognostic (1.31e-3)" "unprognostic (2.19e-2)" 1.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 6.1 2.8 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.0 1.6 0.0 0.1 3.2 0.0 163.0 0.2 0.2 0.4 0.0 0.0 2.2 0.5 0.0 1.3 0.5 53.9 4.2 0.1 0.0 5.5 5.5 3.6 2.4 1.5 4.8 0.4 0.1 0.0 0.5 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 8.9 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.1 0.0 0.6 0.0 1.0 0.1 3.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.2 1.0 0.1 0.1 0.5 0.5 0.1 0.1 0.0 1.2 0.3 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.4 0.1 1.7 0.3 0.8 0.2 0.5 0.0 1.3 2.0 3.6 4.4 1.3 3.5 4.3 4.0 4.8 1.1 5.5 4.2 4.6 1.6 1.5 2.4 5.5 3.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APTX "AOA, AOA1, AXA1, EAOH, EOAHA, FLJ20157" ENSG00000137074 Aprataxin Q7Z2E3 9 32972606-33025168 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064930 Supported Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA064930: " "unprognostic (9.18e-2)" "unprognostic (2.65e-2)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (4.04e-1)" "unprognostic (8.16e-2)" "unprognostic (2.26e-2)" "unprognostic (1.00e-1)" "unprognostic (1.32e-2)" "unprognostic (2.78e-3)" "unprognostic (3.48e-3)" "unprognostic (3.49e-2)" "prognostic favourable (6.01e-5)" "unprognostic (7.87e-2)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (6.50e-2)" 12.9 20.3 17.5 11.2 18.4 19.9 16.5 15.1 21.7 12.0 15.2 19.3 9.3 11.7 14.7 12.9 19.1 14.7 8.0 11.9 13.3 13.9 17.9 23.4 12.6 11.8 16.4 16.5 11.8 14.3 15.8 14.3 12.1 20.2 12.1 18.1 14.6 12.5 11.9 14.1 20.6 13.8 14.6 15.7 11.7 12.5 18.2 14.5 8.8 10.5 12.6 16.1 13.4 12.1 17.1 18.4 16.1 20.8 26.4 19.4 15.0 21.2 16.1 12.3 10.6 12.5 11.0 16.2 14.2 14.8 17.4 19.2 21.4 7.5 16.6 8.6 11.9 11.3 20.0 19.1 21.6 22.4 8.2 9.8 23.1 21.8 14.6 15.8 9.4 14.7 23.4 19.9 25.9 16.6 14.8 16.5 16.2 9.1 14.2 23.2 18.7 17.3 12.8 8.5 11.8 14.3 12.9 8.5 7.2 13.0 11.7 9.5 13.3 6.5 10.2 9.7 12.9 16.7 14.6 7.2 11.8 16.6 14.4 12.9 7.7 9.1 17.7 14.9 13.4 16.3 17.6 17.0 15.2 15.5 18.4 17.1 18.0 14.6 16.1 26.4 20.8 17.9 19.4 15.0 17.5 18.4 15.1 21.7 13.3 13.9 16.4 16.5 20.2 14.5 AQR "fSAP164, IBP160, KIAA0560" ENSG00000021776 "Aquarius intron-binding spliceosomal factor" O60306 15 34851782-34969839 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040624, HPA055647" Enhanced Nucleoplasm Nucleoplasm "HPA040624: , HPA055647: " "unprognostic (1.73e-1)" "unprognostic (3.71e-2)" "unprognostic (2.97e-1)" "unprognostic (1.32e-2)" "unprognostic (1.03e-1)" "unprognostic (9.04e-2)" "unprognostic (4.25e-2)" "unprognostic (1.90e-1)" "unprognostic (5.95e-2)" "unprognostic (2.65e-1)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "prognostic favourable (4.83e-4)" "unprognostic (2.97e-1)" "unprognostic (2.47e-1)" "unprognostic (3.84e-1)" "unprognostic (3.13e-2)" 15.5 15.8 8.0 14.0 12.4 9.7 16.1 11.2 14.3 16.6 11.2 11.8 8.7 9.2 18.5 11.8 18.3 12.3 8.7 9.9 8.4 7.5 14.4 11.2 10.7 12.6 8.7 6.9 15.5 13.6 16.8 13.2 15.3 13.2 12.0 11.8 12.4 15.1 11.3 8.7 14.2 13.0 14.3 8.3 16.8 12.9 15.8 9.2 27.9 14.8 8.5 16.5 15.7 14.9 5.9 5.5 7.1 5.1 4.5 6.5 2.9 5.0 13.0 8.7 9.1 11.8 11.0 4.5 6.2 7.9 8.2 7.4 5.9 3.1 4.1 4.0 10.4 8.0 14.5 8.8 9.2 5.8 5.9 13.2 11.5 5.4 6.7 10.7 6.2 8.5 5.9 6.5 6.9 7.0 9.3 4.1 8.1 3.4 6.1 7.1 8.6 5.4 8.4 14.9 4.1 8.3 8.9 9.5 7.4 10.1 9.6 2.2 6.8 8.3 9.1 6.2 3.4 4.2 5.4 5.0 6.1 8.3 7.7 9.3 6.2 7.1 4.7 2.7 6.5 5.1 5.7 4.0 5.7 6.2 3.8 5.9 5.8 6.4 2.3 4.5 3.0 5.5 4.6 2.9 8.0 12.4 11.2 13.4 8.4 7.5 8.7 6.9 13.2 9.2 ARG1 ENSG00000118520 "Arginase 1" P05089 6 131573144-131584332 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 284.1" "Cell line enhanced" "Detected in some" "Hep G2: 1.6;HL-60: 3.9;RH-30: 1.6;SiHa: 1.8;U-698: 2.2" "Cancer enriched" "Detected in some" 45 "liver cancer: 167.7" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "neutrophil: 24.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 24.4" "Region enhanced" "Detected in single" "cerebellum: 2.7" "Low region specificity" "Detected in single" "HPA003595, CAB009434, HPA024006, CAB056159" Enhanced 15000000 "CAB009434: AB_2058955, CAB056159: , HPA003595: AB_1078190, HPA024006: AB_1844987" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-1)" "unprognostic (9.95e-2)" "unprognostic (7.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (7.55e-3)" "unprognostic (8.35e-2)" "unprognostic (1.25e-2)" "unprognostic (2.90e-2)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (1.79e-2)" 1.0 0.0 0.1 0.1 0.1 34.3 0.6 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.3 0.1 3.0 0.2 0.0 0.1 284.1 5.1 0.8 0.2 0.1 0.4 0.2 0.0 0.1 1.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 14.6 0.1 0.1 0.1 3.5 0.0 0.3 0.1 0.5 0.3 1.7 0.3 0.3 0.7 0.1 0.1 24.4 0.4 0.0 4.7 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.1 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.2 1.6 0.0 3.9 1.3 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.5 0.1 0.3 0.1 0.0 0.0 1.6 0.4 0.0 0.3 0.2 0.1 1.8 0.4 0.2 0.1 0.5 0.0 0.0 0.2 0.3 0.1 1.0 0.1 2.2 0.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.1 24.4 0.0 0.4 0.1 4.7 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.1 ARG2 ENSG00000081181 "Arginase 2" P78540 14 67619798-67651720 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 53.7;thyroid gland: 75.4" "Cell line enhanced" "Detected in many" "HAP1: 25.0" "Cancer enhanced" "Detected in all" "prostate cancer: 49.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000663, CAB009435" Enhanced Supported Mitochondria Mitochondria "CAB009435: AB_2059089, HPA000663: AB_1078192" "unprognostic (8.74e-3)" "unprognostic (3.06e-2)" "unprognostic (1.35e-2)" "unprognostic (2.29e-1)" "unprognostic (2.30e-1)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-3)" "unprognostic (4.62e-3)" "unprognostic (5.37e-2)" "unprognostic (4.66e-3)" "unprognostic (1.72e-1)" "unprognostic (9.39e-2)" "unprognostic (4.26e-1)" "unprognostic (2.31e-1)" "unprognostic (4.34e-1)" "unprognostic (1.26e-1)" 1.5 3.9 2.4 1.7 6.4 0.6 2.7 8.3 5.3 9.3 5.4 0.5 2.0 2.1 3.7 2.3 7.3 0.8 4.9 2.1 3.3 5.5 41.4 2.0 1.7 0.6 3.2 1.7 8.8 2.6 32.1 22.5 4.4 4.6 53.7 1.1 3.4 26.6 3.8 17.2 0.8 10.4 2.2 3.9 0.7 1.4 1.9 2.1 0.1 75.4 13.6 2.2 5.3 4.1 2.5 1.7 2.0 1.4 0.3 2.9 3.4 3.5 0.5 6.2 4.0 0.9 0.0 8.4 2.8 7.5 9.1 15.4 15.3 1.8 6.0 0.7 1.8 0.8 25.0 11.3 11.0 0.2 6.2 2.7 1.1 17.5 2.7 0.6 16.4 0.4 14.8 4.4 21.6 15.3 7.9 0.0 0.6 1.7 0.9 0.6 11.8 0.2 0.2 0.8 6.9 7.4 6.0 13.8 5.2 1.7 1.7 2.6 6.4 0.2 3.1 2.7 6.9 0.2 2.0 0.5 0.9 2.0 5.5 3.1 4.6 0.3 1.4 2.0 1.1 0.5 0.5 0.7 0.3 0.9 1.7 2.5 0.6 0.6 1.7 0.3 1.2 0.1 2.9 3.4 2.4 6.4 8.3 5.3 3.3 5.5 3.2 1.7 4.6 2.1 ARSA ENSG00000100299 "Arylsulfatase A" P15289 22 50622754-50628173 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005554, CAB025183" Enhanced Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" 4500000 "Golgi apparatus" Cytosol "CAB025183: , HPA005554: AB_1078220" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (4.07e-2)" "prognostic favourable (2.96e-5)" "unprognostic (4.66e-2)" "unprognostic (4.40e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-2)" "unprognostic (2.16e-1)" "unprognostic (4.47e-2)" "unprognostic (2.76e-1)" "unprognostic (9.90e-2)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (7.73e-3)" 19.0 15.2 14.0 15.2 15.7 16.6 15.2 11.9 17.9 12.0 20.3 21.4 26.4 30.2 13.3 21.4 15.6 18.5 23.3 18.8 13.4 8.8 17.5 24.1 15.7 16.8 19.1 10.3 9.3 45.4 13.1 20.4 18.5 17.3 15.8 8.8 14.0 36.8 21.9 6.3 11.1 23.4 8.7 13.2 25.6 23.6 27.2 17.9 10.6 18.7 7.5 16.5 14.8 13.3 5.6 15.7 30.1 19.8 3.9 8.9 7.7 4.0 5.7 2.8 5.3 20.5 11.2 6.9 6.6 8.0 2.9 4.9 1.6 6.3 2.7 4.0 10.7 6.3 0.6 6.0 0.4 1.2 4.3 1.6 6.4 5.7 14.2 2.4 16.8 13.3 11.8 4.7 3.0 6.4 1.7 38.4 5.8 4.6 2.1 2.7 0.8 5.6 1.9 0.2 12.6 4.8 6.3 1.3 4.2 9.3 8.3 4.7 3.7 3.0 11.3 2.0 7.8 7.4 1.9 9.1 0.8 2.1 5.9 2.1 6.7 4.3 13.7 17.1 8.9 16.0 7.9 5.6 6.5 7.3 11.2 5.6 3.9 5.3 30.1 3.9 19.8 15.7 8.5 7.7 14.0 15.7 11.9 17.9 13.4 8.8 19.1 10.3 17.3 17.9 ARSB ENSG00000113273 "Arylsulfatase B" P15848 5 78777209-78986087 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 17.2" "Group enriched" "Detected in many" 7 "dendritic cells: 5.5;granulocytes: 17.2;monocytes: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037770, HPA037771" Approved Approved "Golgi apparatus" "Intracellular and membrane" "Golgi apparatus" "HPA037770: AB_10671719, HPA037771: AB_10671720" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.97e-2)" "unprognostic (1.09e-2)" "unprognostic (7.34e-2)" "unprognostic (2.65e-1)" "unprognostic (8.69e-3)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (7.20e-2)" "unprognostic (1.74e-1)" "unprognostic (3.59e-2)" "unprognostic (2.48e-2)" "unprognostic (9.57e-3)" "unprognostic (9.88e-2)" "unprognostic (6.54e-3)" "prognostic unfavourable (3.42e-4)" 15.2 8.4 7.7 9.9 8.9 9.4 11.4 6.2 10.4 7.8 8.7 10.8 2.6 4.0 14.1 6.7 8.6 6.7 12.0 13.0 7.7 5.8 23.2 9.3 10.8 17.2 7.1 6.1 6.1 9.6 10.7 6.1 14.7 7.1 7.5 10.5 12.1 5.2 9.3 5.3 3.4 6.0 18.0 8.3 10.9 7.9 4.1 5.6 7.2 6.4 4.0 6.2 10.3 5.6 1.2 5.5 17.2 5.7 0.1 0.6 1.6 2.3 5.5 9.0 2.9 22.0 8.7 8.3 13.0 11.5 9.7 11.9 4.8 4.2 2.7 14.1 12.7 1.9 3.4 3.7 9.6 23.2 2.6 4.4 5.9 18.6 5.0 4.9 5.2 10.1 1.2 10.2 3.4 11.3 0.9 6.4 9.8 4.5 2.3 9.2 2.7 2.9 3.4 5.3 2.9 6.1 3.0 3.2 7.3 9.7 3.1 5.7 3.4 12.7 7.5 8.7 5.0 3.9 11.6 5.5 9.9 3.6 10.5 10.5 19.7 10.5 5.7 17.2 0.6 4.6 0.4 1.2 0.3 0.3 5.5 1.1 0.2 0.4 3.3 0.1 3.7 4.0 0.5 1.6 7.7 8.9 6.2 10.4 7.7 5.8 7.1 6.1 7.1 5.6 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease mutation, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 71.3;SK-MEL-30: 101.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 27.0;classical monocyte: 53.6;eosinophil: 36.5;intermediate monocyte: 77.9;myeloid DC: 20.8;neutrophil: 73.8;non-classical monocyte: 80.5" "Group enriched" "Detected in all" 6 "dendritic cells: 20.8;granulocytes: 73.8;monocytes: 80.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" 410000 "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favourable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 41.9 16.8 18.5 11.2 20.7 20.7 44.2 17.6 19.1 23.9 18.5 15.4 31.5 11.9 17.6 30.6 19.8 16.2 22.3 120.4 17.5 19.2 45.0 13.2 57.2 40.2 27.0 16.7 13.0 16.5 18.0 28.2 36.5 29.8 19.5 19.7 33.3 20.4 39.4 18.2 16.4 16.4 19.5 40.9 25.9 12.9 8.2 15.9 4.5 73.4 15.1 12.3 31.4 16.0 9.8 20.8 73.8 80.5 6.7 6.0 38.7 8.2 11.5 4.5 11.2 71.3 8.4 7.0 8.4 12.0 4.2 7.4 6.1 11.5 5.1 10.8 9.3 10.9 2.8 4.4 5.1 3.9 6.6 22.8 8.7 16.4 19.5 4.6 25.6 18.1 15.3 6.0 4.1 1.1 4.0 10.9 11.9 8.3 2.5 8.3 5.3 7.1 3.3 4.6 6.9 19.7 47.2 7.4 9.9 7.8 25.9 101.4 8.4 5.3 7.3 5.4 7.8 9.9 4.0 13.4 30.3 3.7 16.0 10.5 4.3 27.0 53.6 36.5 6.0 77.9 5.4 9.8 4.5 4.5 20.8 7.7 5.3 4.8 73.8 6.7 80.5 3.9 4.9 38.7 18.5 20.7 17.6 19.1 17.5 19.2 27.0 16.7 29.8 15.9 ASAH2 ENSG00000188611 "N-acylsphingosine amidohydrolase 2" Q9NR71 10 50182778-50248610 "Enzymes, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "intestine: 43.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" HPA061171 Supported Approved "Focal adhesion sites" "Intracellular and membrane" 1200000 "Focal adhesion sites" "HPA061171: " "unprognostic (3.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.66e-1)" "unprognostic (3.84e-2)" "unprognostic (3.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (4.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.86e-2)" "unprognostic (5.64e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" 0.3 1.1 0.6 0.2 0.9 0.0 0.5 0.5 1.3 1.7 0.5 43.9 0.7 0.3 0.7 0.5 0.2 0.9 0.5 1.4 0.6 1.6 0.4 0.2 1.2 1.4 1.5 0.3 1.0 0.4 0.5 0.3 0.9 0.2 0.8 0.7 33.4 0.7 0.6 0.2 2.5 1.1 0.6 0.1 1.0 0.5 0.9 0.9 0.0 0.0 0.0 2.2 0.1 1.8 1.4 1.6 2.2 2.9 1.1 2.0 2.0 1.3 3.8 3.5 1.0 4.6 0.0 2.2 2.7 1.7 2.1 0.7 4.7 2.3 3.8 1.3 3.8 2.9 1.8 0.4 0.2 0.4 2.6 6.5 7.4 0.8 2.5 1.2 2.5 1.5 1.4 0.1 4.8 4.1 0.0 6.4 1.6 2.1 0.3 2.7 7.3 2.5 1.8 3.3 1.5 1.0 2.0 1.9 4.3 4.7 6.0 1.9 0.2 0.0 5.5 0.0 1.7 0.0 0.0 0.0 0.7 0.0 2.2 0.9 0.4 1.7 0.0 0.1 1.4 2.1 0.0 0.0 0.0 0.9 0.6 0.1 ASCC3 "ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH" ENSG00000112249 "Activating signal cointegrator 1 complex subunit 3" Q8N3C0 6 100508194-100881372 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031608, HPA031609, HPA031610" Enhanced Supported "Golgi apparatus,Cytosol" Cytosol "Golgi apparatus" "HPA031608: AB_10599970, HPA031609: AB_10600777, HPA031610: AB_10611526" "unprognostic (6.79e-2)" "unprognostic (1.46e-2)" "unprognostic (2.96e-3)" "unprognostic (1.12e-1)" "unprognostic (9.70e-3)" "unprognostic (4.56e-2)" "unprognostic (1.50e-1)" "unprognostic (5.14e-2)" "unprognostic (4.02e-1)" "unprognostic (3.34e-1)" "unprognostic (5.08e-3)" "unprognostic (1.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.90e-1)" "unprognostic (1.56e-1)" "unprognostic (1.01e-1)" "unprognostic (1.55e-2)" 15.9 15.4 10.9 15.5 14.5 13.6 13.4 16.1 11.7 16.7 13.2 7.7 10.1 11.4 16.4 12.9 18.4 11.3 11.1 14.9 9.7 8.4 10.4 28.3 12.6 13.1 13.1 7.6 13.8 15.1 25.0 38.6 26.1 10.4 16.4 17.1 6.4 15.4 14.0 13.6 15.3 16.1 12.2 15.5 17.7 11.5 11.7 12.4 25.0 10.6 11.6 15.2 16.0 17.9 8.5 9.4 5.9 6.4 6.0 7.8 1.8 7.0 8.8 13.3 8.2 14.9 19.0 20.7 31.0 20.0 10.7 12.4 18.0 5.7 21.7 6.1 20.8 15.9 11.4 27.5 17.4 13.7 9.8 16.4 16.5 11.7 13.7 17.4 12.7 17.2 14.1 15.6 19.9 19.6 19.4 9.9 29.5 6.8 8.6 5.3 7.0 6.7 10.5 10.1 8.0 10.6 20.0 8.7 6.6 12.9 11.7 5.3 6.5 9.9 26.9 12.0 9.1 10.3 13.0 4.3 3.9 19.4 8.6 13.2 12.5 5.9 3.9 2.4 6.7 6.4 7.8 5.8 5.6 6.0 4.1 8.5 6.5 6.2 0.3 6.0 5.2 9.4 4.3 1.8 10.9 14.5 16.1 11.7 9.7 8.4 13.1 7.6 10.4 12.4 ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503419 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.3;kidney: 33.2" "Cell line enhanced" "Detected in some" "ASC diff: 8.1;ASC TERT1: 6.3;CACO-2: 5.4;HSkMC: 11.4" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Uncertain Cytosol Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" 10.9 4.1 14.5 1.8 37.6 1.7 3.3 3.0 19.4 6.2 3.6 35.2 3.1 9.7 4.1 5.5 4.5 5.0 3.3 2.2 21.9 11.0 33.2 12.6 3.2 1.3 50.2 11.3 2.9 1.0 0.9 0.9 3.1 18.9 4.0 4.6 2.6 1.9 4.8 9.3 4.6 13.3 2.9 22.4 4.6 3.9 5.6 51.3 0.0 1.8 1.1 0.8 4.5 3.5 1.7 1.2 3.6 0.7 1.6 1.3 0.2 0.4 0.2 0.9 0.7 8.1 6.3 0.5 0.4 0.3 0.3 0.3 5.4 0.3 1.1 0.3 1.0 0.5 0.5 0.3 0.4 2.8 0.3 0.5 0.9 0.4 0.9 0.7 0.8 11.4 0.6 0.7 0.2 0.1 0.6 1.9 0.4 0.4 0.3 0.9 0.8 0.5 0.4 0.5 0.9 0.4 1.6 0.7 0.5 1.6 0.6 1.2 0.6 0.3 0.6 1.0 0.7 0.7 0.4 1.2 0.6 0.7 0.4 0.6 0.8 3.4 0.7 0.8 1.2 0.6 1.0 1.1 1.0 0.9 0.5 1.7 1.2 1.3 3.6 1.6 0.7 1.2 0.5 0.2 14.5 37.6 3.0 19.4 21.9 11.0 50.2 11.3 18.9 51.3 ASPG C14orf76 ENSG00000166183 Asparaginase Q86U10 14 104085679-104115581 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 29.7;liver: 88.7" "Cell line enhanced" "Detected in some" "EFO-21: 2.6;HDLM-2: 3.0;HeLa: 2.4;HMC-1: 3.1;RPTEC TERT1: 1.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA069761 Enhanced "HPA069761: " "unprognostic (1.45e-2)" "unprognostic (7.43e-3)" "unprognostic (2.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-2)" "unprognostic (1.74e-2)" "unprognostic (1.72e-2)" "unprognostic (3.47e-2)" "unprognostic (1.98e-1)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "unprognostic (1.10e-1)" "unprognostic (8.75e-2)" "unprognostic (7.98e-2)" "unprognostic (3.85e-1)" "unprognostic (1.52e-2)" "unprognostic (2.32e-2)" 0.7 0.5 0.4 0.4 0.5 0.0 2.1 0.4 0.5 1.5 2.3 0.5 0.4 0.5 1.6 1.0 10.2 2.0 0.8 29.7 0.4 0.0 9.8 88.7 1.3 0.9 0.4 0.4 4.9 0.4 0.7 0.4 0.8 0.7 0.4 0.8 1.2 0.8 0.4 0.4 5.2 0.8 1.1 0.4 0.4 1.6 0.9 0.4 0.4 1.3 0.6 1.7 0.5 2.8 0.2 0.0 1.0 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.2 1.8 0.8 2.6 0.0 0.2 0.0 0.0 0.0 3.0 0.0 0.0 2.4 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.7 0.0 0.7 0.6 1.8 1.9 1.4 1.2 0.0 0.1 0.8 0.2 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.5 0.4 0.0 0.4 0.4 0.7 0.4 ASRGL1 "ALP, ALP1, FLJ22316" ENSG00000162174 "Asparaginase like 1" Q7L266 11 62337448-62393412 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 52.4;cervix, uterine: 68.7;testis: 57.6" "Cell line enhanced" "Detected in many" "EFO-21: 30.0;HAP1: 28.9;RPTEC TERT1: 25.6;SCLC-21H: 39.5" "Cancer enhanced" "Detected in all" "endometrial cancer: 53.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 51.4;eosinophil: 52.4" "Group enriched" "Detected in many" 4 "granulocytes: 52.4;monocytes: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029725, HPA055572, CAB070192" Enhanced Approved Nucleoplasm,Microtubules Microtubules Nucleoplasm "CAB070192: , HPA029725: AB_10602328, HPA055572: AB_2682854" "unprognostic (1.14e-1)" "unprognostic (8.38e-3)" "prognostic favourable (6.14e-4)" "prognostic favourable (1.56e-5)" "unprognostic (5.35e-2)" "unprognostic (8.19e-2)" "prognostic unfavourable (9.46e-4)" "unprognostic (8.67e-2)" "unprognostic (1.85e-1)" "unprognostic (3.54e-2)" "unprognostic (2.71e-1)" "unprognostic (4.44e-1)" "prognostic favourable (4.32e-7)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (5.43e-3)" "unprognostic (1.40e-1)" 3.6 2.6 27.8 3.8 37.0 7.1 4.6 12.3 22.3 68.7 7.9 9.9 2.0 4.1 15.3 7.9 1.4 36.8 9.5 1.7 19.5 19.0 23.8 2.4 6.6 3.3 30.8 11.8 1.6 5.1 1.5 5.7 2.3 16.4 8.6 9.9 4.9 6.4 4.8 2.3 1.2 3.1 3.0 9.6 2.4 5.6 57.6 11.3 2.8 3.7 0.0 3.0 2.9 1.0 0.5 8.2 52.4 14.2 2.5 0.7 4.9 0.8 6.6 7.3 9.4 0.0 0.0 5.8 0.8 0.2 1.3 1.2 10.8 2.9 0.6 30.0 0.1 0.6 28.9 0.3 1.5 1.1 11.9 0.4 9.0 7.8 0.2 8.0 10.8 0.3 0.1 0.6 0.1 13.6 8.0 7.5 0.3 12.6 21.5 5.3 9.9 5.2 8.7 4.4 4.0 25.6 2.0 39.5 5.6 5.6 9.8 4.8 5.2 4.1 0.7 0.1 5.5 0.4 3.2 11.5 10.9 1.0 0.3 4.1 3.3 51.4 14.2 52.4 0.6 10.3 0.4 0.5 0.2 0.7 8.2 0.4 0.5 0.7 3.3 2.5 7.2 1.4 0.1 4.9 27.8 37.0 12.3 22.3 19.5 19.0 30.8 11.8 16.4 11.3 ATAD1 FLJ14600 ENSG00000138138 "ATPase family, AAA domain containing 1" Q8NBU5 10 87751512-87841343 "Enzymes, Predicted membrane proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037569 Uncertain Approved Nucleoli,Mitochondria Nucleoli Mitochondria "HPA037569: AB_10672496" "unprognostic (9.92e-2)" "unprognostic (2.90e-1)" "unprognostic (4.05e-2)" "unprognostic (2.68e-1)" "unprognostic (3.24e-2)" "unprognostic (6.60e-3)" "unprognostic (3.38e-1)" "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (8.45e-2)" "unprognostic (1.35e-3)" "unprognostic (1.67e-2)" "prognostic favourable (3.98e-6)" "unprognostic (2.35e-1)" "unprognostic (3.29e-1)" "unprognostic (3.45e-2)" "unprognostic (4.22e-2)" 16.2 21.3 20.4 15.1 26.2 8.0 19.4 22.4 29.8 19.2 15.9 14.4 16.0 13.5 19.6 17.0 17.3 14.8 13.3 39.9 20.4 22.2 20.6 22.1 14.1 14.2 20.4 17.1 19.1 12.6 25.6 24.9 30.2 31.2 24.3 18.4 19.8 15.8 20.4 32.1 14.4 14.1 18.4 18.2 12.5 14.0 19.8 14.7 18.0 20.1 18.5 15.7 18.9 15.2 9.0 7.3 6.7 7.6 9.8 13.5 7.4 9.8 9.3 11.9 11.3 14.4 12.7 9.0 10.0 16.6 10.3 11.6 8.4 28.6 9.5 7.7 8.3 16.4 9.9 8.5 12.1 8.5 13.4 7.8 13.0 10.3 17.1 21.2 5.4 12.6 23.8 10.9 27.1 6.8 7.6 12.4 11.4 6.0 13.6 14.4 8.8 6.5 9.3 7.6 10.4 15.8 7.6 7.6 16.6 8.8 6.3 20.1 16.5 10.0 8.4 9.4 8.4 6.3 13.0 16.7 15.3 12.2 10.4 14.8 7.2 6.7 3.8 5.7 9.2 5.9 13.5 9.0 10.3 11.4 7.3 7.6 11.8 11.6 2.2 9.8 7.6 5.5 9.3 7.4 20.4 26.2 22.4 29.8 20.4 22.2 20.4 17.1 31.2 14.7 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family, AAA domain containing 2" Q6PL18 8 123319850-123416350 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 53.8" "Cell line enhanced" "Detected in many" "SK-BR-3: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB056158: , HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavourable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavourable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 4.1 4.9 4.6 12.6 9.2 22.8 7.2 5.6 6.9 14.0 8.6 1.5 13.4 5.3 4.7 5.0 10.7 4.7 3.5 13.7 4.2 6.3 2.2 10.1 9.8 13.7 4.0 4.3 9.9 3.9 3.5 18.7 5.2 4.0 11.4 7.5 2.4 6.8 15.4 13.8 7.2 6.6 5.5 4.1 8.8 6.9 20.2 3.4 53.8 4.8 6.3 12.7 9.9 5.9 4.3 2.3 7.2 2.8 4.0 7.4 1.8 25.0 9.8 13.9 4.7 2.5 3.2 6.1 19.7 6.8 17.0 19.0 7.4 10.9 16.4 6.0 6.2 12.0 18.6 6.3 27.3 22.8 9.9 29.5 10.5 15.0 1.0 10.8 14.6 1.0 0.9 16.1 5.4 5.2 13.8 16.8 12.6 26.0 30.9 8.1 2.5 9.8 16.2 16.6 8.9 6.0 11.5 17.9 7.8 28.5 74.4 5.0 15.1 10.2 3.2 12.9 17.8 10.2 23.6 5.4 9.6 15.2 8.4 18.1 10.1 7.2 1.5 5.4 2.9 1.3 4.0 4.3 4.2 4.8 2.3 2.8 2.8 3.0 0.4 4.0 2.8 0.3 7.4 1.8 4.6 9.2 5.6 6.9 4.2 6.3 4.0 4.3 4.0 3.4 ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311817-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Enhanced "Plasma membrane,Cytosol" 3400000 "Plasma membrane, Cytosol" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavourable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavourable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" 19.4 27.4 21.1 23.0 28.4 16.9 24.8 12.1 32.3 20.6 26.7 29.1 18.1 23.4 27.9 15.6 19.1 21.9 19.1 18.2 20.3 21.1 23.1 35.6 17.3 36.1 29.7 19.9 23.4 32.9 25.1 21.1 31.1 24.4 21.9 35.9 19.5 14.4 29.4 35.5 17.0 20.6 26.7 21.7 29.0 20.4 15.0 28.0 46.3 16.1 13.5 35.3 27.6 18.0 21.7 13.4 2.9 8.9 19.6 22.8 10.0 20.2 30.7 17.1 29.1 23.0 23.3 8.6 20.7 18.0 23.7 27.2 59.1 31.8 29.5 25.7 21.6 21.3 37.6 31.2 34.0 21.9 36.4 35.9 26.3 53.0 29.8 44.9 18.4 19.7 24.0 31.6 38.2 15.8 46.3 24.6 32.5 29.9 39.1 21.8 65.9 17.2 36.4 24.7 26.4 25.1 32.7 26.9 18.6 16.6 20.5 23.4 33.6 16.0 13.9 20.1 20.8 25.9 13.0 31.1 40.6 61.2 17.5 25.1 29.0 2.9 6.0 0.1 13.2 8.9 22.8 21.7 18.6 20.0 13.4 13.2 18.9 17.5 0.7 19.6 7.4 11.7 17.7 10.0 21.1 28.4 12.1 32.3 20.3 21.1 29.7 19.9 24.4 28.0 ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677273-25865172 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 12.8;fHDF/TERT166: 18.7;HMC-1: 12.5;RPTEC TERT1: 10.0;SK-MEL-30: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 12 "dendritic cells: 3.0;NK-cells: 4.7;T-cells: 4.0" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain "HPA041496: , HPA042509: " "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavourable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" 7.4 14.1 5.3 5.4 9.8 4.7 5.7 3.4 11.0 5.3 3.3 6.2 1.4 1.5 1.9 2.1 3.7 3.1 7.1 2.9 8.0 5.8 6.0 1.0 12.2 14.8 9.3 9.0 1.6 1.9 1.9 2.5 3.6 11.3 3.6 2.3 4.0 14.4 1.5 0.7 3.3 3.6 5.3 6.4 3.5 4.0 6.0 6.2 1.5 3.0 1.6 3.3 4.2 3.3 0.0 3.0 0.0 0.3 4.7 4.0 1.7 0.0 3.3 0.6 0.0 2.7 2.5 0.0 12.8 6.2 3.9 6.9 0.0 0.0 0.0 0.7 18.7 0.0 6.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.6 0.0 0.5 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.9 0.7 2.3 2.3 0.8 10.0 0.0 0.0 0.0 0.0 0.0 16.9 5.1 0.5 0.0 5.2 0.2 7.5 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.3 0.0 1.9 0.2 1.9 0.0 2.2 2.1 0.4 0.0 4.0 3.7 0.0 4.7 0.1 3.0 0.7 1.7 5.3 9.8 3.4 11.0 8.0 5.8 9.3 9.0 11.3 6.2 ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.8;intestine: 35.4" "Cell line enriched" "Detected in single" 23 "WM-115: 17.4" "Group enriched" "Detected in many" 7 "colorectal cancer: 19.0;pancreatic cancer: 4.2;stomach cancer: 8.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034574 Uncertain "HPA034574: AB_10669992" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.47e-4)" "unprognostic (3.99e-2)" "unprognostic (6.10e-3)" "unprognostic (4.69e-2)" "unprognostic (4.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-2)" "unprognostic (3.42e-2)" "unprognostic (5.12e-2)" "unprognostic (2.38e-3)" "unprognostic (5.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-1)" "unprognostic (2.14e-1)" 0.5 0.4 4.3 4.1 9.4 0.4 0.7 5.1 10.0 1.7 33.8 27.8 1.5 18.9 0.4 11.4 8.2 0.7 12.8 0.5 5.5 2.8 0.5 0.4 0.5 0.4 13.8 6.8 0.4 4.2 0.4 0.4 0.4 13.1 0.5 35.4 0.0 2.8 1.0 0.4 8.4 21.1 1.6 20.2 0.4 4.1 0.7 14.0 0.0 0.5 0.0 2.5 1.8 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 9.4 5.1 10.0 5.5 2.8 13.8 6.8 13.1 14.0 ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485288-47593486 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 55.7" "Cell line enhanced" "Detected in many" "HAP1: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "basophil: 31.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 31.5" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA050808: " "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.93e-2)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-2)" "unprognostic (8.05e-2)" "unprognostic (3.48e-2)" "unprognostic (3.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "prognostic favourable (5.00e-8)" "unprognostic (3.97e-2)" "unprognostic (4.47e-3)" "unprognostic (1.11e-2)" "unprognostic (3.37e-2)" 8.1 9.7 7.6 6.8 8.0 1.4 6.9 3.9 7.5 10.2 7.4 5.2 10.4 4.5 12.9 10.1 15.2 6.7 8.6 7.4 7.3 4.0 14.5 5.8 9.4 6.7 7.0 4.8 10.0 6.2 16.9 18.6 55.7 8.1 8.1 4.5 7.7 7.5 11.5 2.8 14.8 6.0 11.4 8.9 12.7 7.6 3.9 7.3 3.6 10.7 5.4 9.2 9.9 13.1 3.6 1.8 31.5 2.9 1.0 0.9 0.6 1.5 1.0 2.4 1.6 6.8 7.4 0.4 10.5 12.7 5.0 9.1 5.4 9.0 4.7 3.9 16.9 2.7 24.5 8.8 7.8 1.8 1.9 3.7 1.7 0.3 6.0 1.1 2.3 6.3 6.7 9.8 6.6 8.5 0.0 2.5 13.7 0.5 2.5 0.7 0.8 1.3 2.8 5.3 0.0 9.1 1.8 1.6 2.9 4.9 1.2 3.1 2.2 1.2 12.8 12.5 2.5 1.1 4.5 1.1 0.8 0.0 6.1 6.9 4.0 31.5 1.4 0.1 0.6 2.3 0.9 1.3 0.2 0.3 1.8 3.6 0.0 0.4 0.7 1.0 2.9 1.1 0.3 0.6 7.6 8.0 3.9 7.5 7.3 4.0 7.0 4.8 8.1 7.3 ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690329-112887168 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Enhanced Vesicles Vesicles "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favourable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" 11.1 11.5 7.2 8.3 16.4 15.7 7.9 5.0 12.5 13.6 5.8 24.4 8.7 9.5 13.7 9.2 8.5 10.8 14.6 19.6 7.2 5.4 12.9 12.3 36.9 7.5 17.7 6.9 8.6 13.2 36.1 17.8 11.2 12.8 5.0 3.6 10.0 12.0 9.0 11.2 11.4 8.7 9.1 12.5 10.2 6.1 9.7 16.2 2.1 16.4 6.4 6.0 5.7 11.3 4.2 1.1 6.4 3.1 0.0 1.0 0.6 13.8 7.1 9.0 10.6 4.6 6.2 16.1 6.6 3.9 5.7 4.6 22.3 16.1 7.0 8.1 5.6 11.8 8.1 5.5 5.5 7.0 7.6 8.1 5.9 11.6 7.3 15.2 13.3 4.2 4.2 6.8 4.2 14.8 5.6 1.2 3.9 5.2 6.9 9.6 3.9 5.1 6.0 3.6 4.0 30.9 3.2 14.5 4.0 6.4 8.4 5.5 3.2 20.3 9.7 0.0 12.3 7.3 5.0 3.8 7.5 2.9 2.5 14.3 6.2 0.0 2.3 3.1 1.0 3.1 0.6 1.3 0.6 0.5 1.1 4.2 0.7 0.4 6.4 0.0 2.7 1.1 0.1 0.6 7.2 16.4 5.0 12.5 7.2 5.4 17.7 6.9 12.8 16.2 ATP11B "ATPIF, ATPIR, KIAA0956" ENSG00000058063 "ATPase phospholipid transporting 11B (putative)" Q9Y2G3 3 182793500-182921635 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036237, HPA036238" Uncertain Approved "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "HPA036237: AB_10673123, HPA036238: AB_10670792" "unprognostic (4.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "prognostic unfavourable (3.44e-4)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (6.73e-2)" "unprognostic (2.03e-3)" "unprognostic (7.28e-2)" "unprognostic (1.18e-1)" "prognostic unfavourable (1.09e-4)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (3.22e-1)" "unprognostic (8.66e-2)" "unprognostic (1.35e-1)" 16.8 7.9 7.7 19.7 9.8 35.4 17.0 18.4 9.4 20.5 21.6 8.9 14.3 13.6 15.0 11.7 37.3 11.8 12.7 21.1 6.9 5.9 13.7 14.3 19.4 20.3 10.3 5.7 15.2 14.6 21.0 26.0 8.0 8.3 16.8 16.9 9.8 19.7 13.8 13.1 21.8 22.8 16.5 11.3 23.4 27.6 22.8 8.9 49.0 10.8 20.4 21.9 22.7 25.5 3.6 4.2 7.5 1.8 3.0 3.4 1.3 22.2 3.2 7.0 9.8 15.0 16.4 6.5 10.3 14.2 8.0 9.4 7.9 11.6 10.3 17.7 14.8 13.5 8.4 10.6 14.0 22.9 6.7 24.9 4.3 1.7 8.8 19.6 16.0 11.1 12.0 9.0 13.1 12.6 8.8 32.3 12.9 7.5 16.3 6.3 5.0 6.3 6.8 20.6 12.4 9.7 18.8 4.2 7.6 28.7 3.7 12.5 4.0 14.6 12.3 12.2 13.3 10.5 17.9 44.1 39.4 19.4 8.4 8.4 7.1 7.5 1.7 7.2 3.1 1.8 3.0 3.6 2.7 3.1 1.9 2.4 2.3 3.4 6.8 3.0 1.7 4.2 2.0 1.3 7.7 9.8 18.4 9.4 6.9 5.9 10.3 5.7 8.3 8.9 ATP11C "ATPIG, ATPIQ" ENSG00000101974 "ATPase phospholipid transporting 11C" Q8NB49 X 139726346-139945276 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030830 Approved "HPA030830: AB_10601336" "unprognostic (8.94e-2)" "unprognostic (1.00e-2)" "unprognostic (3.06e-2)" "unprognostic (3.42e-3)" "unprognostic (3.08e-1)" "unprognostic (3.46e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (3.65e-2)" "unprognostic (9.75e-2)" "unprognostic (2.73e-1)" "unprognostic (5.18e-2)" 12.8 7.0 4.8 7.6 10.6 4.6 9.6 8.0 5.8 13.1 8.8 5.3 30.2 4.8 12.0 9.5 7.3 9.1 7.4 5.2 6.7 4.5 10.8 41.4 6.7 11.2 9.6 3.2 13.1 4.6 6.8 4.2 4.6 9.5 11.5 6.4 10.7 5.8 21.4 6.6 5.6 7.8 11.3 6.3 14.4 7.1 7.9 9.7 14.9 6.1 4.0 7.4 12.7 12.2 2.8 2.1 5.1 1.7 3.5 2.5 0.5 9.4 4.0 8.3 13.5 12.4 16.9 10.6 11.3 15.2 9.2 12.8 3.5 7.7 13.6 25.6 16.0 7.9 20.0 5.1 14.5 12.4 11.7 6.8 8.9 6.9 13.8 11.9 4.4 11.1 3.4 9.9 8.5 15.8 7.7 10.4 12.1 5.1 10.9 8.1 14.1 7.7 10.9 9.0 11.3 7.7 15.7 6.5 10.8 4.4 0.5 5.9 3.4 6.6 17.7 12.6 4.1 15.2 15.4 3.0 2.9 10.7 5.7 14.9 6.2 5.1 1.5 0.4 1.2 1.0 2.5 2.8 1.4 1.1 1.2 2.7 1.4 2.2 2.8 3.5 1.7 2.1 1.0 0.5 4.8 10.6 8.0 5.8 6.7 4.5 9.6 3.2 9.5 9.7 ATP12A "#945, 2, ATP1AL1, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680411-24712493 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 12.3;lymphoid tissue: 38.4" "Cell line enhanced" "Detected in some" "HEK 293: 1.2;HEL: 3.2;NTERA-2: 1.0;U-266/84: 2.8;U-937: 1.6" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Cell type enriched" "Detected in single" 5 "T-reg: 1.7" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039526 Approved "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" 0.1 0.1 0.1 0.0 0.1 0.0 0.8 0.2 1.3 0.4 0.1 0.0 0.0 0.0 0.2 0.2 12.3 0.1 0.0 0.1 0.3 0.2 8.8 0.1 6.1 0.0 0.1 0.0 0.1 1.0 0.0 0.2 5.8 0.4 0.3 2.2 0.0 0.4 0.0 0.1 9.8 0.1 0.0 0.1 0.1 0.1 1.0 0.0 1.2 0.2 2.9 38.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.3 0.0 0.5 1.2 3.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 2.8 0.1 0.0 1.6 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.1 0.2 1.3 0.3 0.2 0.1 0.0 0.4 0.0 ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Mental retardation, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 195.4;parathyroid gland: 194.4" "Cell line enhanced" "Detected in all" "SK-MEL-30: 248.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced 380000 "CAB018702: AB_626713, CAB069993: AB_2060979" "unprognostic (6.18e-2)" "unprognostic (2.18e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-1)" "prognostic unfavourable (1.42e-4)" "unprognostic (1.80e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (1.65e-1)" "prognostic favourable (8.98e-8)" "unprognostic (4.75e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-2)" "prognostic unfavourable (4.01e-4)" 17.4 25.6 22.4 16.2 40.3 10.5 26.9 74.2 67.4 17.8 121.9 14.2 56.1 92.3 13.1 38.3 34.9 17.7 65.8 41.1 26.1 18.7 162.7 34.6 35.1 9.6 19.2 27.6 17.4 78.6 194.4 25.0 19.2 34.1 22.1 65.7 24.1 84.4 53.7 19.0 40.5 195.4 17.7 20.7 13.7 25.0 17.0 13.9 9.1 101.2 13.7 16.2 14.2 23.1 10.3 22.0 6.4 29.7 10.4 30.2 17.2 32.9 12.2 12.7 6.3 25.5 24.7 65.2 19.8 39.4 24.4 34.7 48.7 23.7 26.1 28.0 23.4 43.1 25.0 41.7 35.5 9.6 27.7 15.2 23.0 41.1 19.5 38.1 21.4 27.5 69.9 28.4 37.5 29.9 25.0 25.3 21.6 65.6 15.4 13.8 29.8 24.5 14.9 29.6 23.1 88.1 34.0 12.5 11.0 30.7 58.4 248.8 15.3 22.1 26.3 13.9 19.5 35.9 40.0 12.2 9.5 20.1 42.7 22.0 81.6 6.4 13.3 6.1 23.2 20.9 24.8 10.3 26.4 24.9 22.0 5.3 30.2 22.0 1.6 10.4 29.7 11.1 20.3 17.2 22.4 40.3 74.2 67.4 26.1 18.7 19.2 27.6 34.1 13.9 ATP1A2 "FHM2, MHP2" ENSG00000018625 "ATPase Na+/K+ transporting subunit alpha 2" P50993 1 160115759-160143591 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 109.8;skeletal muscle: 305.8" "Cell line enhanced" "Detected in some" "AF22: 32.2;HHSteC: 9.4;RH-30: 10.5;U-87 MG: 6.5" "Cancer enriched" "Detected in many" 18 "glioma: 91.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022230 Enhanced "CAB022230: " "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (3.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.83e-1)" "unprognostic (7.98e-2)" "unprognostic (2.16e-2)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.85e-2)" "unprognostic (8.63e-4)" "unprognostic (1.70e-2)" "unprognostic (9.40e-3)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (7.16e-2)" "unprognostic (5.32e-3)" 12.6 3.9 61.4 2.8 80.1 2.3 6.5 30.4 109.8 4.7 6.6 27.4 2.4 3.7 4.2 7.4 15.3 6.0 5.3 35.4 42.2 27.0 3.3 2.5 3.8 2.4 45.6 37.9 9.9 2.6 2.4 4.6 3.6 58.0 13.8 5.6 12.5 3.1 14.2 305.8 2.8 4.4 5.4 51.5 2.7 2.8 3.9 28.3 0.0 2.6 17.7 2.5 5.5 1.3 0.6 1.4 1.7 0.4 0.6 0.5 0.3 0.0 0.0 32.2 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 2.8 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 1.3 0.4 0.3 0.3 0.3 0.2 0.4 0.3 0.2 0.7 0.6 0.3 0.5 1.7 0.6 0.2 1.4 0.2 0.3 61.4 80.1 30.4 52.0 42.2 27.0 45.6 37.9 58.0 28.3 ATP1A3 DYT12 ENSG00000105409 "ATPase Na+/K+ transporting subunit alpha 3" P13637 19 41966582-41997497 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Deafness, Disease mutation, Dystonia, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 146.4;heart muscle: 78.3" "Cell line enhanced" "Detected in many" "Daudi: 20.4;Karpas-707: 13.0;REH: 12.8;SCLC-21H: 48.3;SH-SY5Y: 20.8" "Group enriched" "Detected in many" 6 "glioma: 21.6;testis cancer: 4.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.2;memory CD8 T-cell: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "CAB033630, HPA045367, HPA056446" Enhanced Approved "CAB033630: AB_781528, HPA045367: , HPA056446: " "unprognostic (1.90e-1)" "unprognostic (8.65e-2)" "unprognostic (4.57e-2)" "unprognostic (8.20e-3)" "unprognostic (8.94e-2)" "unprognostic (2.52e-1)" "unprognostic (3.16e-2)" "unprognostic (7.66e-2)" "unprognostic (8.02e-2)" "prognostic unfavourable (3.44e-4)" "prognostic favourable (6.15e-5)" "unprognostic (4.02e-3)" "prognostic unfavourable (3.02e-6)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "unprognostic (3.45e-1)" "unprognostic (1.27e-1)" 1.9 12.8 34.0 2.5 30.8 2.1 1.8 42.8 146.4 1.8 2.4 4.8 0.0 2.4 1.8 1.8 2.0 1.8 1.9 78.3 48.3 54.6 1.8 1.8 1.9 2.3 39.9 42.6 1.8 2.3 1.8 3.0 1.8 94.4 1.8 2.3 17.3 2.2 1.8 1.8 2.0 2.7 2.2 18.5 2.1 2.0 18.6 6.9 0.0 1.8 0.0 2.1 1.9 0.1 0.3 0.1 0.0 0.0 0.1 2.2 0.3 0.0 0.8 0.2 8.5 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.3 1.6 20.4 0.9 0.1 0.2 6.0 0.0 0.2 3.8 1.1 1.7 0.0 0.1 0.0 0.0 6.7 0.0 0.0 0.0 0.1 0.0 0.0 13.0 0.1 0.3 3.7 0.0 1.1 5.2 12.8 7.0 0.6 0.0 0.2 48.3 20.8 0.1 1.5 0.0 1.2 0.9 0.0 1.1 1.1 0.0 0.3 1.3 0.9 4.6 1.9 7.1 0.1 0.0 0.0 0.0 2.2 0.0 0.2 0.3 0.6 1.7 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.1 0.7 0.3 34.0 30.8 42.8 66.6 48.3 54.6 39.9 42.6 94.4 6.9 ATP1A4 ATP1AL2 ENSG00000132681 "ATPase Na+/K+ transporting subunit alpha 4" Q13733 1 160151570-160186977 "Enzymes, Predicted membrane proteins" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 13.1;seminal vesicle: 19.0;testis: 35.8" "Group enriched" "Detected in some" 11 "BEWO: 10.5;HDLM-2: 26.2;RT4: 31.7" "Group enriched" "Detected in some" 8 "breast cancer: 0.8;urothelial cancer: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (1.33e-1)" "unprognostic (4.01e-3)" "unprognostic (2.20e-1)" "unprognostic (1.94e-1)" "unprognostic (2.09e-1)" "unprognostic (8.55e-2)" "unprognostic (1.22e-1)" "unprognostic (7.48e-3)" "unprognostic (2.45e-1)" "unprognostic (8.77e-3)" "unprognostic (1.98e-2)" "unprognostic (3.17e-2)" "unprognostic (2.43e-3)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (4.09e-2)" "prognostic favourable (2.20e-4)" 0.4 0.3 0.4 0.8 0.3 0.0 2.2 0.4 0.3 0.3 0.3 0.0 11.2 0.0 0.2 0.3 0.3 0.3 0.8 0.3 0.3 0.3 0.2 0.2 0.3 3.8 0.3 0.0 0.2 0.2 0.0 0.3 13.1 0.0 0.6 0.0 0.4 1.2 19.0 3.2 0.3 0.5 1.6 0.3 1.1 0.3 35.8 0.0 0.9 0.2 0.2 1.6 8.9 5.9 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.3 0.3 0.3 0.3 0.0 0.0 0.0 ATP2A1 "ATP2A, SERCA1" ENSG00000196296 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1" O14983 16 28878405-28904509 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "skeletal muscle: 456.3;tongue: 209.0" "Cell line enhanced" "Detected in many" "HEK 293: 19.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "NK-cell: 4.7" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in single" 8 "thalamus: 14.3" "Low region specificity" "Detected in all" "CAB002310, CAB032706" Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB002310: AB_564139, CAB032706: AB_2061286" "unprognostic (2.37e-1)" "unprognostic (6.81e-2)" "unprognostic (2.23e-5)" "unprognostic (5.35e-2)" "unprognostic (2.27e-1)" "unprognostic (2.04e-1)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.87e-1)" "unprognostic (5.22e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-4)" "unprognostic (1.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-2)" 7.6 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.1 1.1 5.2 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.6 0.1 12.6 7.0 0.3 456.3 0.2 0.2 0.1 0.1 0.1 0.1 0.9 0.0 0.0 4.2 209.0 6.5 0.2 0.1 1.6 3.1 0.7 0.2 4.7 1.5 0.6 4.8 5.2 9.6 5.7 0.4 1.6 8.9 2.3 1.3 0.4 0.4 2.9 4.4 7.6 2.7 0.4 5.1 2.4 0.1 0.7 3.8 19.8 2.7 11.8 9.0 0.2 1.1 2.5 4.1 1.1 0.6 0.5 0.2 5.1 6.5 0.3 9.7 10.9 6.1 9.6 7.4 16.8 6.8 5.7 0.0 0.6 6.1 4.9 3.3 4.5 3.4 3.4 2.7 2.0 3.0 6.3 5.6 2.8 9.5 5.7 7.4 5.9 15.0 2.9 0.0 0.1 0.7 1.0 0.0 1.3 1.6 1.1 1.0 0.0 0.8 1.4 1.3 0.0 4.7 0.2 3.1 1.5 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 ATP2A2 "ATP2B, DAR, SERCA2" ENSG00000174437 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2" P16615 12 110280756-110351093 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 188.3;skeletal muscle: 319.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062605 Enhanced 38000000 "HPA062605: " "unprognostic (4.81e-2)" "unprognostic (2.16e-2)" "unprognostic (1.87e-1)" "unprognostic (3.41e-3)" "unprognostic (2.50e-1)" "unprognostic (3.98e-3)" "unprognostic (1.91e-2)" "unprognostic (6.20e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (1.36e-3)" "unprognostic (2.26e-1)" "unprognostic (5.62e-2)" "unprognostic (9.93e-2)" 8.4 8.8 7.3 8.5 14.5 5.7 7.5 7.4 20.8 8.2 9.6 8.0 8.3 7.3 9.4 10.3 24.1 9.4 9.3 188.3 10.1 5.0 6.7 11.8 8.9 5.6 5.6 13.1 8.5 7.6 8.7 6.1 8.1 10.2 13.0 11.2 22.3 18.3 9.6 319.7 9.3 9.3 14.3 7.4 5.4 7.9 11.9 7.1 3.1 12.6 51.3 12.7 13.4 11.4 0.8 2.2 0.2 4.4 1.7 1.7 0.7 34.9 69.8 35.4 28.4 23.5 30.2 51.0 43.7 55.0 44.3 29.9 50.5 37.3 43.2 37.0 41.5 51.2 58.5 69.0 50.4 35.7 29.3 37.7 28.0 29.5 40.0 43.0 36.5 31.7 48.6 56.3 54.6 34.2 43.9 21.2 36.0 33.6 23.2 26.7 40.3 35.3 24.6 31.8 35.7 21.8 72.3 37.4 28.1 54.9 45.2 25.5 60.7 23.2 36.7 41.1 22.1 27.3 33.3 43.6 53.0 48.5 37.4 18.6 46.5 0.0 1.9 0.0 1.7 4.4 0.9 0.7 1.3 1.1 1.9 0.8 1.3 1.2 0.2 1.7 2.3 2.2 1.2 0.7 7.3 14.5 7.4 20.8 10.1 5.0 5.6 13.1 10.2 7.1 ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 82.4;salivary gland: 88.1" "Cell line enhanced" "Detected in many" "Daudi: 39.1;HMC-1: 57.9;Karpas-707: 25.3;MOLT-4: 51.8;SK-BR-3: 42.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "cerebellum: 10.9;midbrain: 4.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in some" 15 "cerebellum: 75.4" "Low region specificity" "Detected in many" "HPA007180, CAB010882" Approved 100000000 "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (4.14e-2)" "prognostic favourable (4.69e-5)" "unprognostic (1.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.02e-2)" "prognostic favourable (2.51e-4)" "unprognostic (8.83e-3)" "unprognostic (2.30e-1)" "unprognostic (8.29e-2)" "unprognostic (3.67e-3)" "unprognostic (3.95e-3)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (1.60e-1)" "unprognostic (3.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-3)" 2.1 4.9 0.9 36.9 1.6 24.3 2.7 10.9 1.7 2.3 15.4 1.8 48.8 8.1 3.4 2.8 4.5 2.2 16.0 2.6 0.9 0.7 3.4 1.6 7.8 25.6 4.1 1.4 2.1 20.2 0.0 0.8 1.7 1.4 7.4 9.0 8.7 88.1 47.3 0.9 9.4 26.1 3.0 1.0 36.4 25.5 1.6 1.2 82.4 4.2 6.0 47.5 5.4 2.6 8.3 10.8 21.1 1.0 2.5 7.8 3.9 0.0 1.6 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.3 39.1 2.4 0.1 0.1 0.6 0.0 0.0 4.8 0.4 20.4 1.2 0.0 0.3 22.2 57.9 0.0 0.0 0.1 0.0 0.0 4.1 25.3 0.0 24.3 51.8 23.9 0.2 0.3 5.7 0.0 9.0 0.0 0.7 2.5 0.7 0.3 42.1 0.0 2.6 5.5 0.1 0.0 0.4 0.1 0.0 9.4 2.8 13.8 0.5 15.9 0.0 9.1 1.0 21.1 7.8 0.6 6.1 6.9 4.8 7.2 1.0 8.3 3.6 4.4 9.0 2.5 0.3 10.8 4.2 3.9 0.9 1.6 10.9 1.7 0.9 0.7 4.1 1.4 1.4 1.2 ATP2B1 PMCA1 ENSG00000070961 "ATPase plasma membrane Ca2+ transporting 1" P20020 12 89588049-89709300 "Enzymes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 53.8" "Cell line enhanced" "Detected in many" "hTERT-HME1: 58.4;LHCN-M2: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005605, HPA011166, HPA012945" Enhanced Supported "Plasma membrane" "Plasma membrane" "CAB005605: AB_2061563, HPA011166: AB_1855484, HPA012945: AB_1855483" "unprognostic (6.78e-2)" "unprognostic (5.27e-2)" "unprognostic (1.57e-2)" "unprognostic (8.23e-2)" "unprognostic (1.72e-1)" "unprognostic (6.44e-2)" "prognostic unfavourable (7.74e-4)" "unprognostic (2.77e-2)" "unprognostic (2.46e-2)" "unprognostic (7.82e-2)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (4.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" 8.7 5.1 23.4 12.5 53.8 40.5 8.8 30.9 44.1 9.0 14.0 4.1 4.0 17.8 8.2 5.8 6.5 8.4 11.3 5.2 29.0 11.8 7.4 10.0 9.2 11.8 7.8 31.5 7.6 7.4 13.7 8.7 11.7 9.2 6.4 14.8 2.9 5.6 6.9 10.9 11.3 12.8 8.7 6.1 12.7 12.4 9.8 16.4 5.7 6.3 6.0 12.3 9.9 7.4 27.1 16.2 41.5 25.6 8.4 16.3 6.2 4.1 21.1 8.3 4.0 12.1 19.3 3.8 12.8 41.9 12.4 19.8 8.4 3.9 8.2 0.9 17.7 3.7 7.3 3.5 34.7 2.8 8.5 2.9 7.4 7.4 39.5 12.2 4.9 15.9 6.7 38.6 58.4 3.1 4.8 3.0 90.7 6.6 3.8 5.2 6.5 10.1 5.4 26.8 3.4 11.8 19.3 7.9 4.3 14.8 4.2 3.5 6.1 1.4 2.2 33.7 5.5 12.3 13.9 2.3 3.5 8.8 15.3 3.5 7.4 2.7 13.0 6.7 7.1 13.6 9.0 27.1 12.4 9.0 16.2 27.0 4.6 5.7 41.5 8.4 25.6 2.9 16.3 6.2 23.4 53.8 30.9 44.1 29.0 11.8 7.8 31.5 9.2 16.4 ATP2B2 PMCA2 ENSG00000157087 "ATPase plasma membrane Ca2+ transporting 2" Q01814 3 10324023-10708007 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 55.1;liver: 15.2;salivary gland: 28.6;skeletal muscle: 30.3" "Group enriched" "Detected in some" 4 "EFO-21: 5.3;RPMI-8226: 15.0;SCLC-21H: 5.7" "Cancer enhanced" "Detected in some" "liver cancer: 7.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005606 Enhanced "CAB005606: AB_2243199" "unprognostic (2.04e-1)" "unprognostic (1.26e-2)" "unprognostic (6.84e-2)" "unprognostic (1.59e-2)" "unprognostic (3.59e-1)" "unprognostic (3.62e-1)" "unprognostic (4.09e-2)" "unprognostic (4.65e-1)" "unprognostic (5.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.32e-4)" "unprognostic (2.70e-1)" "unprognostic (1.46e-3)" "unprognostic (1.08e-3)" "unprognostic (1.33e-2)" "unprognostic (8.34e-2)" "unprognostic (7.95e-3)" 1.0 1.5 7.6 1.0 23.0 0.9 1.0 39.9 55.1 3.0 1.0 2.4 0.0 1.0 3.2 1.1 1.1 4.3 1.0 1.0 10.0 6.2 1.1 15.2 1.0 1.0 7.9 14.7 1.0 1.1 0.9 1.7 0.9 15.5 1.0 1.0 0.7 28.6 0.9 30.3 1.3 1.0 2.3 2.5 1.0 1.0 1.5 4.2 0.0 0.9 0.0 1.0 0.9 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 15.0 0.0 0.0 5.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 7.6 23.0 39.9 55.1 10.0 6.2 7.9 14.7 15.5 4.2 ATP2B3 "CFAP39, CLA2, PMCA3, SCAX1" ENSG00000067842 "ATPase plasma membrane Ca2+ transporting 3" Q16720 X 153517676-153582939 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Calmodulin-binding "Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 18.6;brain: 23.2" "Cell line enhanced" "Detected in some" "SCLC-21H: 14.3;SH-SY5Y: 4.2;THP-1: 3.5;U-937: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001583 Enhanced "HPA001583: AB_1079641" "unprognostic (1.35e-1)" "unprognostic (3.07e-2)" "unprognostic (3.28e-1)" "unprognostic (6.82e-2)" "unprognostic (1.30e-1)" "unprognostic (4.32e-2)" "unprognostic (2.67e-1)" "unprognostic (6.34e-2)" "unprognostic (2.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.38e-3)" "unprognostic (3.44e-1)" "unprognostic (2.71e-12)" "unprognostic (1.44e-3)" "unprognostic (2.04e-1)" "unprognostic (2.42e-2)" 0.8 18.6 5.4 0.9 11.3 0.8 0.8 16.1 23.2 0.8 0.9 3.9 0.0 0.9 0.9 2.6 0.8 3.1 0.8 0.8 7.8 5.5 1.0 0.8 0.8 0.8 4.3 11.5 0.8 0.9 0.8 1.2 1.7 13.6 0.8 0.8 1.4 1.3 1.3 0.8 0.9 0.9 0.9 1.4 0.8 0.8 1.1 0.9 0.0 0.8 0.0 0.8 0.8 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.3 4.2 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 11.3 16.1 20.7 7.8 5.5 4.3 11.5 13.6 0.9 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626561-203744081 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 42.6;BJ hTERT+: 60.6;fHDF/TERT166: 45.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" 21000 "Plasma membrane" "CAB016118: AB_2061729, HPA040431: " "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavourable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 23.0 14.0 24.8 10.8 14.2 5.9 11.6 9.4 23.6 32.6 44.2 7.5 12.9 5.3 69.6 13.1 20.4 27.0 13.9 24.0 13.1 8.7 5.0 14.2 16.1 5.3 6.4 19.2 21.9 6.4 8.0 4.8 16.2 9.3 17.0 13.4 11.6 7.5 31.5 5.4 22.0 13.2 74.2 5.7 4.8 16.4 13.1 7.5 9.0 8.3 8.4 7.7 32.8 14.2 1.0 4.2 4.5 2.2 4.2 10.4 2.6 9.3 1.7 3.4 3.2 26.5 39.5 18.3 42.6 60.6 7.3 6.2 0.8 4.8 2.1 6.2 45.9 9.2 5.0 5.9 7.6 27.0 1.8 6.3 8.5 0.5 9.5 9.0 11.2 28.7 5.8 23.2 3.6 13.8 2.7 4.3 5.3 0.5 9.1 3.0 2.1 5.3 4.7 2.6 3.4 2.4 0.8 1.0 1.5 15.0 2.2 6.8 2.0 4.4 12.1 17.6 2.6 29.5 10.2 2.9 4.2 1.2 17.6 6.5 5.2 3.0 2.2 0.0 10.4 1.5 7.9 1.0 6.6 8.3 2.4 0.3 1.6 4.2 4.5 4.2 2.2 4.2 6.3 2.6 24.8 14.2 9.4 23.6 13.1 8.7 6.4 19.2 9.3 7.5 ATP2C1 "ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1" ENSG00000017260 "ATPase secretory pathway Ca2+ transporting 1" P98194 3 130850595-131016712 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010207, HPA035116, HPA069684" Supported Supported "Golgi apparatus" 28000 "Golgi apparatus" "CAB010207: AB_2061744, HPA035116: AB_10673106, HPA069684: " "unprognostic (1.52e-1)" "unprognostic (1.37e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "prognostic unfavourable (5.06e-6)" "unprognostic (7.66e-2)" "unprognostic (6.52e-2)" "unprognostic (2.45e-1)" "prognostic unfavourable (1.52e-4)" "unprognostic (8.44e-2)" "prognostic favourable (1.55e-4)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "unprognostic (3.06e-1)" 18.6 22.9 29.6 14.5 29.4 20.4 36.8 24.5 34.6 22.2 21.6 23.0 14.3 14.4 19.3 18.0 16.9 23.4 16.8 19.2 31.6 32.3 28.0 17.1 30.7 16.0 31.8 25.4 18.5 14.6 47.6 31.0 19.6 26.7 54.0 22.4 18.1 20.3 16.6 16.1 21.3 16.0 19.2 44.6 11.1 18.7 16.0 25.6 20.5 21.7 15.5 15.4 19.3 29.6 4.7 7.6 21.6 7.0 8.7 7.2 4.9 36.2 14.2 14.3 13.8 40.0 32.5 15.4 39.6 52.8 19.9 25.2 23.1 29.9 13.1 27.5 37.4 43.2 26.8 21.8 29.2 28.4 9.6 35.0 15.1 10.7 25.6 13.9 42.7 25.4 22.0 20.9 23.8 21.1 10.0 23.9 24.5 16.1 13.6 11.1 16.2 15.5 9.9 14.3 20.7 36.7 24.4 22.1 13.2 34.0 10.6 19.9 15.8 11.5 28.7 21.2 11.9 27.3 18.2 15.5 18.8 19.5 21.9 10.5 17.7 21.6 7.0 12.1 6.3 6.0 5.9 4.7 6.2 5.6 7.6 2.9 4.3 4.3 3.5 8.7 7.0 6.6 7.2 4.9 29.6 29.4 24.5 34.6 31.6 32.3 31.8 25.4 26.7 25.6 ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.0;salivary gland: 35.8" "Cell line enhanced" "Detected in some" "HaCaT: 6.3;MCF7: 16.3;RT4: 12.9;SK-BR-3: 22.7;T-47d: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 24 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 24 "granulocytes: 2.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" "Plasma membrane, Focal adhesion sites" "HPA052262: , HPA075812: " "unprognostic (2.28e-2)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "prognostic favourable (6.20e-6)" "unprognostic (2.04e-1)" "unprognostic (2.41e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.92e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.16e-1)" "unprognostic (8.37e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-4)" "unprognostic (1.39e-1)" 0.3 0.0 2.1 8.0 1.5 6.1 2.5 0.2 2.0 3.5 23.0 0.5 1.9 16.3 1.8 1.9 2.7 4.0 18.8 0.4 1.8 1.9 2.6 0.2 21.9 0.2 1.3 0.7 1.3 0.5 0.0 2.9 4.8 0.7 7.9 21.9 1.0 35.8 0.2 0.9 15.2 14.5 0.5 0.6 0.2 3.4 0.4 0.4 0.3 8.2 2.2 8.1 4.8 7.8 0.0 0.0 2.7 0.0 0.0 0.1 0.0 4.1 0.3 0.5 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.0 3.9 3.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 12.9 3.3 0.0 0.0 22.7 0.2 7.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 2.1 1.5 0.2 2.0 1.8 1.9 1.3 0.7 0.7 0.4 ATP4A ATP6A ENSG00000105675 "ATPase H+/K+ transporting alpha subunit" P20648 19 35550043-35563658 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "stomach 1: 120.1" "Cell line enhanced" "Detected in some" "THP-1: 1.1;U-138 MG: 1.5" "Cancer enriched" "Detected in single" 21 "stomach cancer: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA039154 Enhanced 790000 "HPA039154: AB_10672772" "unprognostic (3.54e-2)" "unprognostic (6.98e-3)" "unprognostic (2.77e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-1)" "unprognostic (9.68e-2)" "unprognostic (1.47e-3)" "unprognostic (3.90e-3)" "unprognostic (3.92e-2)" "unprognostic (4.86e-2)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" 0.1 0.2 0.1 0.1 0.6 0.0 0.1 0.1 0.6 0.1 0.1 3.4 0.1 0.0 0.1 0.1 4.9 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 2.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 2.1 0.1 0.1 120.1 0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.1 0.0 1.5 0.3 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.1 ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56646068 "Enzymes, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria 100000000 Mitochondria "CAB017527: AB_1121153, HPA001520: AB_1078243, HPA001528: AB_1078242" "prognostic unfavourable (7.17e-6)" "unprognostic (5.69e-2)" "unprognostic (1.08e-2)" "unprognostic (7.24e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.92e-2)" "unprognostic (8.19e-3)" "unprognostic (2.38e-2)" "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "prognostic favourable (1.43e-9)" "unprognostic (2.79e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.30e-2)" 41.3 66.2 32.4 34.1 53.4 39.3 33.1 55.4 92.6 26.1 73.0 34.4 36.1 68.1 27.9 28.5 58.6 28.5 36.9 225.0 33.2 34.9 95.2 85.7 28.3 39.2 40.5 35.5 25.1 42.7 85.2 30.1 31.3 69.6 29.0 78.5 42.8 64.7 38.1 236.2 42.3 74.6 35.5 24.9 33.5 51.0 31.4 18.3 47.5 38.4 123.6 45.8 36.6 32.8 41.2 91.7 40.2 90.1 36.3 46.6 105.6 65.7 80.0 63.6 98.1 57.4 61.4 112.4 66.9 62.5 115.7 65.9 129.9 73.4 117.0 72.5 82.4 88.2 134.0 81.1 104.8 54.8 92.8 128.3 74.7 79.6 71.1 143.5 90.9 75.2 81.9 90.4 116.8 95.0 115.5 134.9 97.0 61.0 106.3 84.4 107.0 154.1 102.4 71.2 149.1 126.0 117.2 72.8 64.7 102.2 146.4 113.7 137.4 108.5 64.4 45.6 50.8 66.5 72.2 65.1 80.9 121.0 68.6 96.0 69.8 40.2 64.6 34.6 40.2 80.6 44.9 41.2 38.0 42.7 91.7 31.7 31.1 36.7 17.8 36.3 90.1 46.3 46.6 105.6 32.4 53.4 55.4 92.6 33.2 34.9 40.5 35.5 69.6 18.3 ATP6V1A "ATP6A1, ATP6V1A1, VA68, Vma1, VPP2" ENSG00000114573 "ATPase H+ transporting V1 subunit A" P38606 3 113747019-113812056 "Disease related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.6" "Group enriched" "Detected in all" 6 "dendritic cells: 16.4;granulocytes: 33.6;monocytes: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006910, HPA035083, HPA035084" Approved Supported Nucleoplasm,Vesicles,Cytosol 2700000 "Nucleoplasm, Vesicles" Cytosol "CAB006910: , HPA035083: AB_2674453, HPA035084: AB_2674454" "unprognostic (1.32e-1)" "unprognostic (8.68e-2)" "unprognostic (5.87e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.00e-1)" "unprognostic (3.43e-2)" "unprognostic (2.90e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-2)" "unprognostic (5.19e-3)" "prognostic favourable (3.82e-12)" "unprognostic (8.82e-2)" "unprognostic (2.46e-3)" "unprognostic (2.43e-1)" "unprognostic (1.52e-2)" 12.8 19.8 24.1 10.4 33.2 7.4 12.7 34.8 52.8 14.0 11.1 10.3 5.6 9.3 7.5 8.2 13.2 10.0 10.8 4.7 26.2 38.2 47.9 18.2 12.3 11.4 25.4 25.0 6.2 10.5 39.3 13.5 12.3 52.0 11.2 11.8 14.7 18.0 8.4 4.5 12.6 7.9 8.2 13.6 13.7 10.9 8.9 8.3 9.6 21.0 5.7 13.6 10.2 8.2 3.8 16.4 33.6 15.4 3.8 3.4 6.0 25.0 11.4 14.4 12.5 30.3 13.6 15.3 13.6 20.8 14.3 19.8 21.5 20.2 20.5 32.3 19.8 16.3 32.4 17.9 18.8 9.3 8.9 18.2 17.7 16.5 25.1 13.3 21.3 18.3 12.4 18.5 12.9 23.2 20.8 15.6 21.2 16.4 9.7 6.0 18.0 14.3 8.4 10.4 23.3 39.1 23.9 27.9 10.3 23.8 16.2 17.8 24.6 10.8 21.3 13.3 10.0 9.1 8.1 16.3 17.5 19.0 26.2 16.9 14.8 9.2 15.4 5.2 2.8 11.7 2.6 3.8 2.6 2.7 16.4 2.9 2.5 2.9 33.6 3.8 9.5 4.6 3.4 6.0 24.1 33.2 34.8 52.8 26.2 38.2 25.4 25.0 52.0 8.3 ATP7A MNK ENSG00000165240 "ATPase copper transporting alpha" Q04656 X 77910656-78050395 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012887, HPA048107" Approved Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA012887: AB_1845205, HPA048107: " "unprognostic (3.14e-2)" "unprognostic (3.48e-1)" "unprognostic (4.90e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-3)" "unprognostic (2.59e-2)" "unprognostic (3.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.30e-2)" "unprognostic (1.14e-1)" "prognostic favourable (8.38e-4)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (3.69e-1)" "unprognostic (2.52e-1)" 9.8 7.4 2.6 8.6 4.6 6.4 8.5 2.3 2.9 8.2 7.7 5.9 9.6 4.8 9.5 7.6 10.0 5.7 4.5 5.1 2.9 2.8 9.0 3.3 9.3 9.3 4.1 1.7 7.3 6.3 13.2 15.9 5.0 4.3 8.2 4.4 5.2 12.3 10.3 6.1 15.9 8.5 7.8 6.3 10.8 7.0 2.7 6.0 15.6 6.0 7.1 11.7 11.8 7.0 2.3 1.4 10.7 2.4 1.7 3.0 1.2 2.5 6.7 4.5 4.6 4.3 4.5 0.8 3.9 5.4 2.3 4.8 0.9 3.0 3.7 5.8 3.8 3.1 5.8 3.1 4.4 5.5 4.0 1.9 6.5 0.7 5.4 3.3 3.5 4.8 1.3 5.0 1.5 6.1 15.3 14.4 4.3 2.2 3.5 1.1 1.3 1.4 2.9 7.5 12.6 3.9 7.2 1.4 17.1 9.6 2.4 4.9 1.8 1.1 7.7 3.1 3.1 4.3 1.5 4.7 8.3 4.3 5.1 2.0 4.7 8.3 2.0 5.5 2.4 1.9 1.2 2.0 1.7 1.7 1.3 2.3 2.1 3.0 10.7 1.7 2.4 1.4 0.6 1.2 2.6 4.6 2.3 2.9 2.9 2.8 4.1 1.7 4.3 6.0 ATP7B WND ENSG00000123191 "ATPase copper transporting beta" P35670 13 51930436-52012125 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 18.5;liver: 13.5" "Cell line enhanced" "Detected in many" "BEWO: 18.8;CACO-2: 10.8;HEL: 28.6;Hep G2: 9.9;RPTEC TERT1: 16.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA009137, HPA013187" Supported Supported "Golgi apparatus" "Golgi apparatus" "HPA009137: , HPA013187: AB_1845206" "unprognostic (1.13e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "prognostic unfavourable (5.01e-4)" "unprognostic (3.49e-1)" "unprognostic (5.51e-2)" "unprognostic (1.55e-2)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (5.77e-2)" "unprognostic (8.29e-2)" "unprognostic (1.17e-1)" "unprognostic (3.26e-3)" "unprognostic (4.66e-2)" "unprognostic (3.54e-1)" "unprognostic (6.21e-3)" "unprognostic (1.40e-1)" 3.4 0.7 1.8 2.4 2.9 1.8 1.6 7.0 2.8 1.4 6.8 1.1 1.1 10.5 1.6 1.9 1.1 1.9 18.5 1.8 2.1 2.1 2.1 13.5 1.2 1.1 1.6 1.1 2.0 1.7 7.7 1.2 7.1 3.5 1.9 2.6 1.4 3.0 1.1 1.1 0.7 9.6 1.5 1.1 1.6 4.5 7.1 1.6 1.1 1.1 1.1 1.1 2.1 1.1 0.0 0.0 1.0 0.3 0.0 0.5 0.1 0.4 1.6 2.9 2.6 0.6 0.5 18.8 0.8 0.2 0.9 0.6 10.8 0.1 0.0 0.3 1.4 0.2 2.0 2.4 0.6 0.2 4.0 28.6 0.3 9.9 0.9 0.3 6.7 1.2 2.8 0.1 1.1 2.0 7.6 0.0 0.8 0.5 0.1 0.7 0.9 0.9 1.0 0.8 0.0 16.7 1.8 2.2 1.2 1.0 1.6 1.1 4.5 0.2 1.1 0.1 1.0 1.6 0.3 0.3 0.4 0.1 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 1.8 2.9 7.0 2.8 2.1 2.1 1.6 1.1 3.5 1.6 ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657105 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 38.9" "Cell line enhanced" "Detected in many" "AN3-CA: 16.8;Daudi: 27.6;HEL: 9.7;REH: 9.5;SH-SY5Y: 9.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Supported Vesicles 20000 Vesicles "HPA052935: " "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favourable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" 5.3 8.6 14.2 8.0 29.6 18.5 4.8 7.2 32.0 3.1 11.3 27.3 8.4 4.2 3.4 11.6 2.9 3.5 2.8 8.0 13.7 8.8 4.0 2.1 10.6 12.5 18.0 17.4 15.1 10.0 38.9 6.9 2.6 15.3 7.9 10.7 3.9 4.4 15.2 16.9 3.2 8.1 3.1 23.1 7.8 10.5 2.8 24.9 8.9 34.9 1.9 10.3 4.5 4.0 4.4 3.8 0.9 3.3 3.2 7.3 0.9 0.0 0.1 0.2 16.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.2 27.6 7.8 0.1 1.4 4.0 0.0 0.0 4.4 2.7 9.7 0.9 0.4 0.0 2.3 0.2 0.3 0.0 0.0 0.0 0.1 0.0 3.1 0.0 1.2 3.5 0.8 1.2 0.3 9.5 0.0 3.1 6.0 0.3 3.0 9.2 0.2 5.8 0.0 1.9 0.0 0.2 0.0 1.3 0.3 0.0 1.1 0.0 5.6 0.4 3.3 0.1 0.0 1.0 0.9 6.0 0.4 3.2 2.6 1.9 6.5 0.9 4.4 2.9 7.3 0.9 3.2 3.3 3.8 1.4 0.9 14.2 29.6 7.2 22.1 13.7 8.8 18.0 17.4 15.3 24.9 ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25372071-26025851 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 34.9;pituitary gland: 37.0;testis: 10.4" "Cell line enriched" "Detected in some" 6 "HMC-1: 21.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.3;naive CD8 T-cell: 3.3" "Lineage enriched" "Detected in single" 12 "T-cells: 3.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Enhanced Supported "Nucleoplasm,Plasma membrane" "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: " "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" 1.1 4.9 11.2 1.4 11.4 0.8 2.2 34.9 30.2 1.1 1.3 1.3 0.0 1.4 2.1 4.8 0.9 0.9 1.0 1.0 9.4 11.8 1.3 0.8 2.3 1.9 6.7 10.4 1.2 1.9 0.9 37.0 1.2 19.8 1.1 1.3 3.1 1.0 1.0 1.3 0.9 1.5 1.0 3.5 1.3 1.8 10.4 1.4 0.0 1.0 0.0 1.2 1.2 0.3 0.0 0.0 0.2 0.0 0.2 3.3 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 1.0 0.0 0.6 1.4 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 21.9 0.2 0.0 0.0 0.0 0.5 0.0 0.0 1.7 0.3 3.7 0.0 2.0 0.7 0.0 2.7 1.0 0.2 0.1 3.3 0.0 0.2 0.3 0.1 0.0 0.4 0.2 0.1 1.1 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.8 0.6 0.0 0.0 2.3 3.3 0.2 0.2 0.0 0.0 0.7 0.6 11.2 11.4 34.9 18.4 9.4 11.8 6.7 10.4 19.8 1.4 ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803101 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" "Disease mutation, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 27.1;HBF TERT88: 24.3;RT4: 57.5" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA018673, HPA018674" Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" "Plasma membrane" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favourable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favourable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" 3.8 2.3 0.0 1.8 0.0 0.0 3.4 0.0 0.3 4.5 21.3 8.9 2.4 0.8 6.7 2.6 4.8 1.8 0.2 0.0 2.1 3.0 3.6 0.0 0.1 0.7 10.7 2.7 1.1 1.3 6.0 19.3 5.8 2.8 0.4 3.6 11.1 2.0 0.2 1.2 13.3 0.0 5.7 0.2 12.8 5.4 6.0 2.0 4.7 2.1 0.7 1.3 0.3 10.1 3.4 0.1 0.1 3.5 6.4 4.9 19.6 19.1 20.6 12.9 2.6 8.8 0.7 5.9 27.1 15.0 0.1 4.1 24.3 0.2 0.4 0.1 0.9 0.9 1.1 0.2 0.1 1.0 3.7 6.2 10.9 10.8 0.1 0.4 11.9 4.8 0.2 0.2 0.2 1.0 0.1 0.1 0.2 2.8 57.5 0.4 0.3 0.4 12.1 0.1 3.7 0.6 12.4 16.8 0.6 2.7 4.5 0.2 0.1 0.2 0.4 0.2 0.9 0.8 2.1 0.5 1.3 0.9 1.0 2.7 1.0 0.7 0.5 6.0 0.9 1.0 4.7 0.7 1.2 2.0 0.4 0.3 ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325553-154351307 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 3.1;T-cells: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046680 Approved "HPA046680: " "unprognostic (1.68e-1)" "unprognostic (3.68e-1)" "unprognostic (8.40e-2)" "unprognostic (5.16e-2)" "unprognostic (4.52e-1)" "unprognostic (8.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.69e-1)" "prognostic favourable (1.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.89e-3)" "unprognostic (7.77e-3)" "unprognostic (6.58e-2)" "unprognostic (3.19e-2)" "prognostic unfavourable (5.29e-5)" 13.6 7.0 5.5 15.0 7.1 3.4 11.9 26.8 8.9 29.1 11.2 7.4 11.5 8.6 28.9 15.2 14.4 21.5 18.4 11.7 7.0 6.8 6.6 2.6 12.2 16.1 6.2 5.8 27.5 5.3 5.1 13.9 10.9 6.1 15.3 6.8 12.5 5.4 16.4 4.3 6.1 11.8 29.4 5.1 14.7 11.4 12.7 5.1 18.9 11.2 8.1 13.6 20.5 24.9 0.6 0.7 3.1 0.0 0.9 6.5 1.0 0.7 5.0 6.4 6.6 41.0 27.8 0.1 15.4 25.7 8.9 10.7 0.1 0.2 0.6 8.2 37.1 3.1 7.6 1.8 6.2 16.9 6.2 6.4 6.2 5.8 12.5 0.0 5.0 17.9 0.4 13.6 13.0 13.7 12.7 15.5 7.6 6.6 12.0 0.7 15.2 6.4 13.4 4.4 22.9 1.7 0.1 5.7 7.9 4.0 0.8 9.6 4.7 4.8 12.0 13.6 6.8 17.0 4.6 21.5 26.3 3.8 4.7 0.7 8.2 3.1 0.0 3.0 2.2 0.0 1.5 0.6 3.5 3.7 0.0 0.4 2.9 2.5 0.1 0.9 0.0 0.7 6.5 1.0 5.5 7.1 26.8 8.9 7.0 6.8 6.2 5.8 6.1 5.1 ATP8B3 ATPIK ENSG00000130270 "ATPase phospholipid transporting 8B3" O60423 19 1782075-1812276 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 55.8" "Cell line enhanced" "Detected in many" "HMC-1: 10.5;Karpas-707: 18.4;U-266/70: 15.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "intermediate monocyte: 6.9" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (6.50e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (6.05e-5)" "unprognostic (6.66e-2)" "unprognostic (7.91e-2)" "unprognostic (1.86e-2)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (2.55e-3)" "unprognostic (1.28e-2)" "unprognostic (6.15e-3)" "prognostic unfavourable (4.80e-9)" "unprognostic (8.05e-2)" "unprognostic (3.20e-1)" "unprognostic (3.19e-2)" "unprognostic (1.19e-1)" 0.6 3.1 0.2 3.1 0.2 7.1 0.6 0.2 0.7 1.5 0.7 0.2 0.2 0.4 1.8 4.3 0.6 0.6 1.0 2.2 0.3 0.2 0.4 1.0 1.9 1.1 0.2 0.5 1.9 0.3 0.3 0.6 0.5 0.4 0.5 0.4 1.1 0.5 1.6 0.2 0.8 0.7 1.0 0.7 4.8 0.4 55.8 0.0 5.5 0.7 1.2 1.5 0.8 1.0 0.1 1.2 1.7 6.9 2.2 2.8 1.2 0.6 5.1 0.6 0.8 0.7 0.5 0.0 2.0 3.0 2.0 1.9 0.0 2.0 2.2 2.3 1.5 0.1 0.4 0.0 0.9 2.1 0.0 0.6 2.4 0.9 0.2 1.3 10.5 0.2 0.1 0.0 2.1 0.5 1.6 18.4 3.3 0.0 1.3 3.9 0.1 2.4 2.2 0.4 0.2 2.7 0.1 0.0 0.7 0.5 0.0 0.3 0.6 6.4 4.8 0.1 4.0 0.7 2.1 15.4 7.5 0.6 3.9 6.4 2.6 0.0 2.2 1.7 1.9 6.9 0.8 0.0 1.4 1.1 1.2 0.1 0.6 1.9 0.6 2.2 1.8 0.5 2.8 1.2 0.2 0.2 0.2 0.7 0.3 0.2 0.2 0.5 0.4 0.0 ATP8B4 "ATPIM, KIAA1939" ENSG00000104043 "ATPase phospholipid transporting 8B4 (putative)" Q8TF62 15 49858238-50182817 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.1;cervix, uterine: 26.0;endometrium 1: 18.2" "Cell line enhanced" "Detected in some" "HMC-1: 18.6;NB-4: 7.1;THP-1: 12.0;U-937: 37.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 6.9;NK-cell: 10.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040254 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA040254: AB_10673028" "unprognostic (6.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.39e-2)" "unprognostic (2.96e-3)" "unprognostic (3.25e-1)" "unprognostic (6.51e-3)" "unprognostic (1.03e-1)" "unprognostic (4.87e-3)" "unprognostic (1.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.20e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" 2.3 1.2 1.6 1.5 2.1 28.1 1.0 0.6 0.9 26.0 1.5 1.7 1.6 0.4 18.2 3.5 0.6 9.5 3.1 0.8 2.5 0.9 1.0 1.2 3.2 0.7 2.7 0.1 3.9 0.4 0.2 1.1 2.9 2.1 0.7 1.2 0.8 0.9 0.6 0.4 0.5 1.1 2.7 3.1 2.3 0.6 0.9 4.6 0.8 0.5 0.8 2.1 1.3 1.5 0.0 2.2 6.9 1.7 10.6 0.5 0.8 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.1 0.0 3.0 0.6 0.0 0.0 5.2 18.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 12.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.4 37.6 0.0 6.9 1.7 2.4 0.5 0.8 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.8 10.6 0.3 0.0 0.0 0.8 1.6 2.1 0.6 0.9 2.5 0.9 2.7 0.1 2.1 4.6 ATP9A "ATPIIA, KIAA0611" ENSG00000054793 "ATPase phospholipid transporting 9A (putative)" O75110 20 51596514-51768634 "Enzymes, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 64.7" "Cell line enhanced" "Detected in many" "EFO-21: 28.8;SK-BR-3: 27.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 6.3;NK-cell: 2.2" "Group enriched" "Detected in many" 5 "granulocytes: 6.3;NK-cells: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020699, HPA035630" Enhanced "CAB020699: , HPA035630: AB_10669526" "unprognostic (5.19e-2)" "unprognostic (5.28e-2)" "unprognostic (3.46e-1)" "unprognostic (1.05e-1)" "unprognostic (3.76e-1)" "unprognostic (1.37e-1)" "unprognostic (3.76e-2)" "unprognostic (4.79e-2)" "unprognostic (7.45e-2)" "unprognostic (1.58e-1)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "prognostic favourable (5.67e-5)" "unprognostic (5.82e-2)" "unprognostic (5.81e-1)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" 18.5 8.2 23.7 3.9 31.8 2.0 11.2 29.8 64.7 5.6 12.2 19.9 8.2 9.1 8.6 13.1 8.8 16.9 8.2 7.7 24.3 26.8 6.8 5.4 6.7 2.6 21.1 23.9 13.2 10.0 22.7 8.3 3.6 22.5 14.3 11.3 4.1 14.9 11.3 9.2 4.1 11.5 8.7 18.9 2.2 14.0 12.4 15.8 0.8 18.7 2.9 2.4 7.4 5.6 0.0 0.0 6.3 0.2 2.2 0.8 1.8 9.5 8.2 6.7 15.1 19.9 14.9 0.1 3.4 6.6 2.2 0.7 18.8 19.9 0.0 28.8 14.2 7.7 8.9 5.0 2.3 7.4 2.7 0.0 9.1 7.5 2.7 0.0 0.0 4.9 10.2 0.5 1.4 12.2 0.0 0.0 2.6 13.4 0.7 0.0 1.2 10.4 1.5 0.0 0.0 4.6 13.5 12.8 9.1 13.8 27.6 5.1 5.2 0.2 8.0 19.0 5.1 7.4 1.4 0.0 0.1 0.3 5.0 0.0 1.7 6.3 0.0 0.0 0.8 0.2 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.4 2.2 0.1 0.0 0.0 1.8 23.7 31.8 29.8 34.9 24.3 26.8 21.1 23.9 22.5 15.8 ATP9B ATPIIB ENSG00000166377 "ATPase phospholipid transporting 9B (putative)" O43861 18 79069285-79378287 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029364 Approved "HPA029364: AB_10602595" "unprognostic (2.84e-3)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (6.51e-3)" "unprognostic (7.32e-2)" "unprognostic (7.66e-4)" "unprognostic (2.45e-2)" "unprognostic (7.43e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (1.61e-1)" "unprognostic (2.93e-1)" "unprognostic (1.92e-3)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.05e-2)" "unprognostic (1.09e-2)" 14.5 11.0 11.7 16.8 11.6 30.1 11.7 16.8 15.2 14.3 10.7 17.5 15.2 7.1 21.8 17.6 11.3 11.9 14.5 10.7 11.4 8.2 13.1 16.7 13.9 13.2 10.8 9.7 18.2 14.3 25.8 15.5 10.9 11.3 12.8 11.4 12.3 14.2 17.3 18.8 13.3 9.1 14.8 17.1 9.7 11.5 22.1 12.4 19.3 14.6 9.6 16.4 14.6 13.3 9.8 8.4 14.2 16.3 8.6 12.2 6.9 15.4 8.1 11.3 12.5 5.9 9.9 8.8 8.3 5.6 5.0 4.2 8.7 11.0 8.6 13.9 6.0 7.0 9.3 4.6 8.1 13.2 3.9 10.1 9.3 6.1 7.8 18.4 10.9 7.9 5.9 8.1 5.0 6.9 9.7 21.8 7.0 13.5 12.0 7.2 16.1 10.1 11.5 9.4 11.5 7.1 13.4 8.4 8.8 9.3 9.8 5.7 11.5 11.0 12.1 10.5 17.1 4.7 5.5 10.9 17.8 19.4 6.1 12.2 10.8 14.2 12.0 9.1 8.4 10.1 9.8 9.0 9.6 8.1 8.4 9.8 12.2 9.5 13.0 8.6 16.3 8.0 7.4 6.9 11.7 11.6 16.8 15.2 11.4 8.2 10.8 9.7 11.3 12.4 ATRX "JMS, MRX52, RAD54, XH2, XNP" ENSG00000085224 "ATRX, chromatin remodeler" P46100 X 77504878-77786269 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001906, CAB009372, HPA064684, CAB068176" Supported Supported "Nuclear bodies" "Nuclear bodies" "CAB009372: AB_2061023, CAB068176: , HPA001906: AB_1078249, HPA064684: " "unprognostic (1.77e-2)" "unprognostic (1.55e-1)" "unprognostic (6.65e-2)" "unprognostic (4.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.15e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (5.80e-2)" "unprognostic (5.14e-3)" "unprognostic (1.50e-1)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-1)" 16.4 16.6 24.5 18.9 29.3 24.3 16.3 48.2 26.4 20.6 15.4 7.1 18.9 10.2 20.2 17.1 13.5 13.8 13.4 15.1 22.9 15.8 16.6 12.2 15.9 18.6 21.1 21.3 25.4 18.3 35.7 28.1 15.9 20.2 18.4 12.6 7.1 15.8 16.5 20.1 14.1 13.5 22.3 15.3 20.1 15.6 6.5 22.4 23.7 19.8 12.7 16.5 19.9 21.1 21.9 12.8 21.5 11.5 14.6 17.7 5.7 15.1 24.4 25.1 16.8 12.5 16.8 8.9 13.1 12.1 9.7 11.5 8.3 13.3 21.0 13.5 13.9 13.5 20.0 7.8 16.6 11.8 13.1 12.7 29.0 6.1 6.8 16.5 4.4 11.1 7.7 14.3 13.7 17.1 14.9 24.2 12.1 11.9 12.7 8.6 18.1 18.9 20.6 34.6 10.8 9.5 20.3 14.3 24.7 26.4 10.4 8.7 8.3 8.4 23.6 13.7 21.3 15.4 9.2 7.2 22.3 18.9 10.1 13.1 12.1 21.3 6.9 13.8 17.7 8.7 17.1 19.2 16.3 13.7 5.1 21.9 16.8 13.5 21.5 14.6 11.5 12.8 12.8 5.7 24.5 29.3 48.2 26.4 22.9 15.8 21.1 21.3 20.2 22.4 ATXN3 "ATX3, JOS, MJD, SCA3" ENSG00000066427 "Ataxin 3" P54252 14 92044496-92106625 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB021976, HPA024123, HPA069338" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB021976: , HPA024123: AB_1845133, HPA069338: " "unprognostic (1.06e-2)" "unprognostic (2.93e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-2)" "unprognostic (5.76e-2)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (9.85e-3)" "unprognostic (1.69e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-2)" "unprognostic (3.06e-2)" "unprognostic (2.03e-2)" "unprognostic (8.94e-3)" "unprognostic (4.22e-1)" "unprognostic (1.64e-1)" "unprognostic (1.11e-1)" 17.8 10.3 10.2 9.1 11.6 14.3 12.8 18.7 12.1 16.0 11.8 12.2 11.9 6.4 17.9 12.4 17.7 9.5 11.2 10.4 9.0 9.9 9.9 16.0 12.3 11.6 16.3 9.5 14.0 10.3 11.9 17.2 11.7 13.8 15.8 11.7 8.6 11.4 10.2 6.1 21.0 8.7 20.6 16.5 12.6 9.0 14.8 14.3 16.2 11.5 12.0 15.6 15.4 13.6 9.8 14.5 11.4 18.8 7.0 8.5 5.3 5.6 11.1 10.0 9.3 14.6 14.3 19.6 6.4 10.4 8.2 11.4 8.0 15.7 11.5 12.8 10.5 9.8 7.7 14.0 18.1 13.1 2.3 4.9 5.4 11.7 12.1 8.6 8.8 11.6 12.5 14.3 15.0 12.6 6.5 8.6 12.4 21.9 9.0 7.8 7.1 9.2 7.2 18.5 6.5 10.5 12.8 3.4 6.0 15.5 6.6 8.8 12.3 6.0 6.7 8.1 11.9 5.2 3.4 7.5 12.5 10.6 6.0 8.5 4.7 11.4 13.4 9.4 5.9 14.5 7.0 7.1 6.9 6.5 14.5 9.8 7.6 8.5 11.3 7.0 18.8 8.4 6.8 5.3 10.2 11.6 18.7 12.1 9.0 9.9 16.3 9.5 13.8 14.3 ATXN3L MJDL ENSG00000123594 "Ataxin 3 like" Q9H3M9 X 13318236-13320399 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024123, HPA027539" Uncertain "HPA024123: AB_1845133, HPA027539: AB_10602435" 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101360417-101383519 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 128.4" "Cell line enhanced" "Detected in some" "A549: 6.1;CACO-2: 3.4;Hep G2: 2.4" "Cancer enriched" "Detected in many" 42 "liver cancer: 181.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Uncertain Vesicles 470000 Vesicles "HPA021251: AB_1845247, HPA021330: " "unprognostic (2.53e-2)" "unprognostic (1.81e-1)" "unprognostic (9.97e-2)" "unprognostic (9.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.68e-2)" "prognostic favourable (4.97e-4)" "unprognostic (2.14e-2)" "unprognostic (6.19e-2)" "unprognostic (4.43e-4)" "unprognostic (3.65e-1)" "unprognostic (2.15e-1)" "prognostic unfavourable (4.24e-7)" "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.8 0.0 0.1 0.1 0.2 128.4 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.2 0.0 0.7 0.1 0.1 6.1 0.4 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.3 3.4 0.1 0.6 0.2 0.0 0.3 0.1 0.2 0.5 0.3 0.1 0.5 0.2 2.4 0.0 0.9 0.3 0.0 1.0 0.1 0.0 0.0 0.7 0.4 0.5 0.1 0.2 0.3 1.0 0.7 0.2 1.1 0.2 0.6 0.2 0.3 0.4 0.4 0.2 0.5 0.0 0.2 0.1 0.6 0.6 0.2 0.4 0.4 0.6 0.5 0.5 0.2 0.6 0.3 0.2 0.0 0.7 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 BACE1 BACE ENSG00000186318 "Beta-secretase 1" P56817 11 117285207-117316259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "brain: 53.0;pancreas: 161.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016358 Approved Supported "Plasma membrane" "Plasma membrane" "CAB016358: AB_626716" "unprognostic (7.96e-3)" "unprognostic (8.05e-2)" "unprognostic (3.55e-2)" "unprognostic (3.05e-3)" "unprognostic (8.94e-2)" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.60e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (8.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "prognostic unfavourable (6.76e-4)" 6.5 7.1 12.1 3.8 18.8 2.2 5.5 9.6 22.4 9.8 4.6 42.5 2.7 3.4 9.3 5.6 7.6 8.6 9.1 5.9 16.9 12.4 6.8 12.1 7.3 2.8 28.8 15.0 11.4 161.1 12.8 4.2 6.3 26.4 6.5 4.7 6.9 5.3 9.9 6.2 7.2 3.6 11.7 53.0 5.7 4.9 4.1 21.4 0.0 6.3 2.3 2.8 6.7 5.5 4.0 2.2 0.7 3.2 2.2 6.7 1.1 3.9 4.6 9.6 14.7 32.0 34.5 0.4 21.2 18.5 10.3 8.4 3.6 6.2 0.7 5.2 38.3 6.9 10.3 6.1 8.5 2.3 5.5 2.3 7.9 4.3 15.8 0.8 0.5 29.9 9.5 13.2 12.8 8.9 0.8 0.4 18.9 14.2 0.6 1.9 6.2 10.4 1.8 4.3 0.8 4.4 2.2 12.5 14.0 7.9 1.0 2.3 10.2 2.7 12.1 18.6 2.0 19.4 6.8 0.3 0.3 0.4 8.7 1.2 13.0 0.6 2.0 0.7 2.0 3.2 5.2 4.0 6.7 5.3 2.2 1.8 3.1 2.7 0.0 2.2 1.3 1.3 6.3 1.1 12.1 18.8 9.6 21.7 16.9 12.4 28.8 15.0 26.4 21.4 BACE2 "AEPLC, ALP56, CEAP1, DRAP" ENSG00000182240 "Beta-site APP-cleaving enzyme 2" Q9Y5Z0 21 41167801-41282518 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 16.9;SK-BR-3: 28.6;SK-MEL-30: 22.2;WM-115: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 4.8;eosinophil: 8.4" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.4" "Low region specificity" "Detected in all" HPA035416 Approved "Intracellular and membrane" "HPA035416: " "unprognostic (1.71e-2)" "prognostic unfavourable (1.11e-4)" "unprognostic (5.23e-2)" "unprognostic (8.12e-3)" "prognostic unfavourable (5.86e-4)" "unprognostic (1.52e-2)" "unprognostic (2.58e-2)" "unprognostic (2.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.49e-1)" "unprognostic (3.46e-2)" "unprognostic (8.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (5.83e-2)" 16.1 2.5 1.4 5.9 1.6 0.9 13.8 0.9 2.0 9.0 11.0 3.4 5.6 5.1 10.3 10.7 13.0 6.8 38.9 7.2 1.7 1.6 11.4 4.4 4.9 21.6 2.7 0.5 8.4 29.0 3.3 2.2 17.2 4.4 22.7 7.4 8.7 28.3 4.4 10.6 5.5 5.4 7.8 5.9 7.0 31.6 5.1 1.4 1.3 9.9 7.6 14.3 11.8 33.6 1.0 0.0 8.4 0.0 0.3 0.0 0.0 16.9 1.6 5.7 0.0 1.5 1.6 0.0 4.2 0.0 2.9 2.5 0.0 6.5 0.0 8.0 5.3 5.3 0.0 10.0 1.0 0.0 8.4 3.3 1.9 0.0 0.7 0.0 8.0 4.1 1.9 0.3 2.1 8.4 0.0 0.0 4.0 3.1 1.9 0.0 4.4 8.7 0.6 0.0 6.3 5.2 1.1 0.2 0.0 0.3 28.6 22.2 8.0 0.0 8.3 4.7 3.4 3.8 6.0 0.0 0.0 0.0 9.8 0.0 20.3 4.8 0.0 8.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 1.6 0.9 2.0 1.7 1.6 2.7 0.5 4.4 1.4 BAP1 "hucep-6, KIAA0272, UCHL2" ENSG00000163930 "BRCA1 associated protein 1" Q92560 3 52401013-52410350 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004322, HPA028814, HPA028815, HPA055560" Approved Enhanced Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: , HPA055560: " "unprognostic (1.52e-1)" "unprognostic (7.96e-2)" "unprognostic (1.96e-2)" "unprognostic (6.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-2)" "unprognostic (9.41e-3)" "unprognostic (8.53e-3)" "unprognostic (1.33e-1)" "unprognostic (3.15e-1)" "unprognostic (4.64e-3)" "unprognostic (3.30e-3)" "prognostic favourable (3.29e-7)" "unprognostic (6.37e-2)" "unprognostic (1.91e-1)" "unprognostic (5.54e-2)" "unprognostic (2.92e-1)" 13.8 17.6 35.6 14.7 33.3 37.3 13.5 21.8 50.4 12.5 17.0 16.3 11.5 12.4 14.7 14.6 21.2 12.1 15.7 16.4 41.5 15.5 16.6 19.0 14.9 15.2 19.4 27.6 16.9 16.3 30.0 11.1 14.8 19.6 14.4 14.9 15.6 17.9 14.6 24.8 40.5 13.9 14.5 10.0 16.1 13.3 37.3 14.7 18.6 15.3 12.9 16.0 14.1 11.7 5.5 8.4 11.3 5.0 3.0 8.5 3.9 15.3 17.5 21.2 18.0 20.5 13.2 23.9 15.2 19.7 24.7 19.2 21.1 14.4 22.0 7.6 21.2 12.5 22.3 24.5 15.8 21.8 21.1 27.3 37.0 21.8 19.1 25.6 24.3 19.7 32.9 27.3 14.7 19.7 23.3 19.5 18.6 13.3 30.3 35.1 23.9 21.3 13.1 17.2 21.7 15.2 24.9 8.1 26.1 18.7 5.4 22.2 15.3 35.4 21.1 22.4 20.6 26.8 28.2 29.6 38.9 31.5 24.4 27.0 26.4 3.4 5.0 7.4 8.5 3.9 4.0 5.0 6.8 6.9 3.3 5.5 4.9 6.4 11.3 3.0 3.1 8.4 6.0 3.9 35.6 33.3 21.8 50.4 41.5 15.5 19.4 27.6 19.6 14.7 BCHE "CHE1, CHE2, E1" ENSG00000114200 Butyrylcholinesterase P06276 3 165772904-165837472 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 145.4" "Cell line enriched" "Detected in some" 9 "Karpas-707: 128.6" "Group enriched" "Detected in many" 6 "glioma: 24.0;liver cancer: 13.7;melanoma: 18.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001560 Approved "Secreted to blood" 13000000000 "HPA001560: AB_1078271" "unprognostic (4.74e-2)" "unprognostic (2.00e-1)" "unprognostic (9.21e-4)" "unprognostic (8.19e-8)" "unprognostic (2.66e-2)" "prognostic unfavourable (1.06e-4)" "unprognostic (1.44e-1)" "unprognostic (5.04e-2)" "unprognostic (6.15e-2)" "unprognostic (9.59e-2)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" "unprognostic (3.18e-3)" "unprognostic (4.46e-5)" "unprognostic (2.17e-2)" "unprognostic (5.92e-2)" "unprognostic (4.26e-4)" 14.0 3.9 6.7 6.2 4.3 0.4 1.9 3.6 9.1 24.4 15.5 4.7 8.3 1.8 20.2 13.4 20.0 18.0 2.2 7.8 6.1 4.4 2.8 145.4 3.7 0.7 5.5 2.7 10.3 1.1 0.4 1.2 0.5 4.7 4.7 5.3 0.7 1.0 10.5 1.1 2.8 6.4 13.9 3.4 3.7 1.9 1.8 6.1 1.0 0.8 0.4 0.5 9.7 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 14.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.2 0.0 0.0 0.0 5.3 0.0 0.0 0.9 0.0 0.9 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 4.1 0.2 0.0 1.3 0.6 0.0 128.6 0.0 0.0 0.0 0.0 0.3 0.1 0.0 4.7 10.7 0.1 0.0 0.0 0.1 0.0 0.0 7.4 5.7 0.0 0.0 3.2 0.0 0.0 1.3 0.5 0.0 0.2 1.3 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 4.3 3.6 4.3 6.1 4.4 5.5 2.7 4.7 6.1 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "Bloom syndrome RecQ like helicase" P54132 15 90717327-90816165 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 36.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 1.8 0.4 3.1 11.4 1.5 5.5 0.6 4.7 2.6 0.7 1.9 0.9 0.5 1.4 1.2 1.1 2.9 0.4 1.3 1.0 2.3 2.4 0.9 0.5 2.0 7.7 2.8 0.2 0.9 0.4 0.0 1.2 3.6 0.5 0.7 2.5 0.7 7.8 0.0 1.7 0.6 2.8 0.5 1.9 6.7 1.4 4.9 0.5 36.7 0.6 3.1 9.3 1.4 0.7 7.4 1.2 4.3 1.6 4.6 5.0 1.6 5.4 7.8 8.7 5.1 0.0 0.4 5.5 4.1 1.2 4.7 5.1 6.8 3.8 14.1 2.6 1.1 9.1 13.4 3.7 6.1 8.5 9.9 14.7 8.4 2.2 0.0 14.1 7.3 0.0 0.0 4.7 2.4 3.3 12.7 4.4 4.9 3.4 10.6 7.8 9.3 1.7 10.8 16.4 5.4 1.1 9.8 6.5 6.1 3.3 4.4 2.6 3.1 11.6 1.8 3.4 6.3 3.5 8.7 3.2 13.1 14.7 1.9 10.0 5.8 2.5 1.0 4.3 3.1 1.2 4.8 7.4 2.8 3.8 1.2 4.3 2.0 2.2 0.8 4.6 1.6 1.2 5.0 1.6 3.1 1.5 4.7 1.7 2.3 2.4 2.8 0.2 0.5 0.5 BLMH BH ENSG00000108578 "Bleomycin hydrolase" Q13867 17 30248195-30292056 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 67.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039548, HPA064307" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" 59000000 "Nucleoplasm, Nuclear bodies, Cytosol" "HPA039548: AB_10805479, HPA064307: AB_2685241" "unprognostic (6.85e-2)" "unprognostic (2.79e-1)" "unprognostic (1.48e-1)" "unprognostic (2.46e-1)" "unprognostic (1.76e-1)" "unprognostic (2.54e-2)" "unprognostic (3.91e-3)" "unprognostic (2.07e-1)" "unprognostic (2.05e-3)" "unprognostic (6.69e-3)" "unprognostic (1.95e-3)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.22e-3)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-1)" 11.2 8.3 9.0 17.1 10.2 8.5 14.2 12.1 14.5 10.5 9.8 8.5 9.6 6.7 13.1 12.2 15.7 8.4 10.1 9.7 7.5 7.2 13.6 7.5 13.6 20.3 9.5 8.5 8.8 15.3 15.0 8.3 14.6 9.2 8.4 8.5 7.3 12.8 9.5 15.0 67.5 10.0 15.7 11.1 13.2 9.2 12.4 8.6 24.7 9.3 15.5 13.6 10.8 11.7 4.6 6.6 0.9 5.7 9.8 17.3 6.3 10.1 16.1 15.6 10.8 10.7 11.5 7.5 9.5 5.9 15.0 13.0 23.6 3.0 30.3 17.0 7.6 7.1 33.7 13.0 12.7 8.0 26.5 18.6 14.5 20.0 15.6 33.8 11.5 13.5 0.9 11.7 6.8 22.0 39.6 12.4 6.2 7.7 41.8 24.7 14.9 7.5 36.3 40.5 20.0 12.0 9.1 36.0 12.9 8.4 16.4 10.3 11.2 17.5 14.0 9.3 18.7 4.1 16.8 15.0 30.8 40.9 7.1 0.0 12.4 0.0 5.7 0.9 10.5 3.9 17.3 4.6 12.6 13.7 6.5 4.2 11.6 12.3 0.7 9.8 1.9 6.6 12.4 6.3 9.0 10.2 12.1 14.5 7.5 7.2 9.5 8.5 9.2 8.6 BMP1 PCOLC ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22164736-22212326 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "lung: 72.2;placenta: 106.2" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" 2100000 "HPA014572: AB_1845390" "unprognostic (1.24e-1)" "unprognostic (8.01e-2)" "unprognostic (3.75e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-2)" "unprognostic (6.76e-2)" "unprognostic (9.53e-2)" "unprognostic (2.64e-3)" "unprognostic (1.66e-1)" "unprognostic (9.75e-3)" "unprognostic (7.05e-3)" "unprognostic (3.14e-2)" "prognostic unfavourable (3.37e-9)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-3)" "unprognostic (3.34e-2)" 6.9 11.7 2.7 3.6 4.6 1.1 5.9 7.8 4.2 8.1 5.8 3.1 3.7 4.4 9.4 5.2 4.8 7.7 5.4 3.4 2.6 1.3 4.9 9.2 72.2 3.2 3.4 1.5 5.2 3.7 2.8 2.2 106.2 3.5 6.5 4.7 4.6 2.4 4.6 2.4 6.8 5.7 11.0 3.6 3.2 2.9 2.2 3.6 1.0 7.1 2.4 2.9 9.9 9.5 0.0 0.9 0.1 1.4 0.8 2.2 0.4 4.6 4.8 1.3 6.2 15.3 11.3 6.8 20.3 16.9 10.4 9.6 2.5 3.0 1.1 12.7 18.6 10.2 1.6 5.4 2.0 1.0 2.1 1.7 7.3 2.9 12.5 0.7 3.5 12.9 8.5 8.1 2.6 10.0 2.2 2.1 5.6 1.7 0.5 1.0 0.8 2.6 1.1 3.3 4.9 9.0 0.7 0.8 3.3 14.6 0.8 3.3 0.9 2.0 12.7 2.7 6.0 6.5 6.0 1.0 0.6 0.2 5.3 2.7 7.5 0.0 1.4 0.0 2.2 0.7 1.4 0.0 0.4 1.0 0.0 0.0 0.3 1.7 0.1 0.8 0.5 0.9 0.0 0.4 2.7 4.6 7.8 4.2 2.6 1.3 3.4 1.5 3.5 3.6 BPNT1 ENSG00000162813 "3'(2'), 5'-bisphosphate nucleotidase 1" O95861 1 220057482-220090462 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048461 Approved Approved "Nuclear speckles" 170000 "Nuclear speckles" "HPA048461: " "unprognostic (6.42e-2)" "unprognostic (4.69e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (5.19e-3)" "unprognostic (7.65e-2)" "unprognostic (2.07e-2)" "unprognostic (3.00e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (6.69e-2)" "unprognostic (2.87e-1)" "prognostic favourable (6.38e-4)" "unprognostic (1.82e-2)" "unprognostic (6.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" 11.1 24.1 12.7 22.2 17.2 2.9 13.4 13.7 16.5 12.9 27.9 15.9 14.4 30.5 10.6 8.0 14.9 11.5 16.1 11.6 11.3 10.8 31.0 17.0 11.5 21.5 14.0 10.6 13.5 8.6 14.1 20.2 12.7 11.9 9.6 22.5 11.8 22.2 12.2 7.6 10.6 49.0 12.3 17.6 12.0 12.9 10.4 13.3 15.6 13.8 12.6 28.8 13.5 10.4 18.9 10.9 11.6 8.5 12.1 13.8 7.6 11.7 9.7 7.3 5.8 13.0 10.4 10.9 15.8 7.7 13.6 12.6 12.7 23.8 59.4 20.8 10.2 8.5 14.7 13.2 11.0 21.3 17.1 10.7 12.5 15.6 7.6 28.4 10.1 9.8 6.3 20.1 7.5 10.6 18.5 5.9 13.0 6.6 16.3 7.8 6.2 11.9 11.7 21.0 16.8 16.9 16.1 13.5 11.1 19.9 24.0 13.0 18.8 9.8 17.7 8.5 6.6 11.8 19.5 10.4 25.2 28.1 7.6 10.6 19.2 11.6 7.8 5.0 11.0 8.5 8.7 18.9 11.3 11.0 9.0 14.1 13.8 10.2 1.1 12.1 7.8 10.9 11.5 7.6 12.7 17.2 13.7 16.5 11.3 10.8 14.0 10.6 11.9 13.3 BRIP1 "BACH1, FANCJ, OF" ENSG00000136492 "BRCA1 interacting protein C-terminal helicase 1" Q9BX63 17 61681266-61863521 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Cell line enhanced" "Detected in many" "MCF7: 41.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 2.2;granulocytes: 2.1;T-cells: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005474 Approved Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA005474: AB_2667333" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "prognostic favourable (3.45e-5)" "unprognostic (6.85e-4)" "unprognostic (3.09e-1)" "prognostic favourable (3.62e-4)" "unprognostic (2.60e-3)" "unprognostic (5.60e-2)" "unprognostic (5.66e-3)" "unprognostic (6.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.75e-2)" "unprognostic (3.41e-12)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (3.96e-2)" "unprognostic (3.62e-3)" 1.0 0.9 0.7 6.3 3.5 9.1 1.1 0.6 1.4 1.4 2.6 0.2 0.6 2.8 1.5 1.2 3.7 0.8 1.8 0.4 0.5 0.5 0.6 2.3 1.3 4.0 0.5 0.9 2.1 1.3 0.1 0.4 1.7 0.7 1.0 2.8 0.4 1.4 0.0 0.4 2.7 5.5 1.0 0.5 2.3 1.3 10.8 0.4 30.1 0.4 2.0 6.6 1.3 1.7 2.2 0.5 2.1 0.3 0.6 3.7 0.5 12.3 4.2 12.2 6.9 0.4 1.1 2.7 11.4 6.7 12.2 15.8 4.3 3.9 7.3 2.6 2.4 4.5 6.3 2.3 16.4 1.8 7.7 7.5 6.7 5.3 0.1 9.6 4.4 0.2 0.1 9.7 2.6 2.6 5.2 5.0 7.6 41.4 15.2 3.3 2.6 3.6 9.5 23.4 3.5 1.6 5.6 4.9 12.7 4.4 1.5 1.8 4.1 3.7 2.2 18.0 13.1 6.6 13.1 3.1 6.0 7.9 3.7 4.6 4.5 2.1 0.3 1.5 0.5 0.2 0.6 2.2 1.2 0.6 0.4 1.8 1.8 0.9 1.0 0.6 0.2 0.5 3.7 0.5 0.7 3.5 0.6 1.4 0.5 0.5 0.5 0.9 0.7 0.4 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15702950-15738313 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 59.5;bone marrow: 54.9;intestine: 61.3" "Cell line enhanced" "Detected in many" "THP-1: 36.3;TIME: 20.0;U-937: 23.7;WM-115: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 52.7;neutrophil: 59.5" "Group enriched" "Detected in many" 105 "dendritic cells: 16.6;granulocytes: 59.5;monocytes: 52.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" 170000000 "HPA050121: " "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 14.3 2.0 1.1 5.6 2.0 54.9 6.6 0.8 1.5 7.2 33.8 1.5 2.1 20.4 6.4 7.0 4.6 5.6 10.3 14.5 1.8 0.8 6.6 3.7 9.4 9.6 1.3 1.9 5.5 1.0 0.4 1.3 8.0 1.3 7.5 4.0 5.4 2.8 2.2 3.4 3.5 61.3 7.9 1.5 13.6 2.4 2.4 1.2 2.8 3.5 2.9 1.8 7.5 16.1 0.4 16.6 59.5 52.7 0.1 0.3 19.6 0.2 5.4 0.5 0.4 13.2 3.1 0.7 10.3 0.9 9.4 10.6 0.1 5.6 0.3 0.9 5.2 0.1 1.5 0.2 8.0 0.3 0.2 2.4 0.3 0.2 3.4 3.2 7.1 2.7 0.7 6.0 0.5 1.4 0.3 0.2 5.5 0.1 1.0 1.9 1.2 1.1 0.3 0.7 0.2 0.3 0.3 0.7 2.0 0.2 0.3 6.8 0.2 36.3 20.0 0.3 0.4 3.7 0.4 0.2 0.0 0.2 1.3 23.7 21.6 7.6 52.7 3.9 0.2 19.8 0.3 0.4 0.1 0.1 16.6 0.2 0.2 0.1 59.5 0.1 13.6 5.5 0.2 19.6 1.1 2.0 0.8 1.5 1.8 0.8 1.3 1.9 1.3 1.2 BTD ENSG00000169814 Biotinidase P43251 3 15601341-15647640 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052275 Uncertain "Secreted to blood" 2900000000 "HPA052275: " "unprognostic (6.04e-2)" "unprognostic (2.42e-1)" "unprognostic (9.37e-3)" "unprognostic (5.84e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-2)" "unprognostic (6.37e-3)" "unprognostic (4.26e-2)" "unprognostic (3.29e-2)" "unprognostic (1.23e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "prognostic favourable (2.60e-9)" "unprognostic (2.44e-2)" "unprognostic (4.90e-2)" "unprognostic (1.67e-3)" "unprognostic (3.73e-2)" 18.5 17.9 7.5 3.9 10.2 4.4 13.5 17.0 11.8 11.2 28.1 19.6 12.2 25.3 12.3 34.1 7.1 10.3 10.4 6.9 8.0 6.8 20.0 50.7 8.2 5.2 12.3 9.5 17.2 26.6 19.6 11.1 10.7 9.3 10.7 9.4 20.0 11.6 12.1 6.9 6.5 40.5 7.9 8.8 7.6 12.9 15.0 12.6 5.9 14.8 3.8 6.2 11.7 9.1 8.4 13.7 31.0 11.9 7.5 15.6 8.7 3.8 10.8 3.3 3.2 28.2 7.8 19.6 7.0 9.4 8.3 15.0 3.8 10.3 1.0 8.4 16.1 4.3 2.6 8.3 9.7 3.3 5.5 5.9 14.5 11.6 6.8 2.9 6.9 9.5 8.6 21.8 2.2 15.9 3.8 13.7 23.3 4.6 1.6 3.4 3.6 6.0 2.1 8.2 13.0 8.0 7.8 2.3 5.7 8.3 2.0 11.0 10.2 5.6 10.8 9.0 6.9 8.3 4.4 3.2 4.8 1.2 10.5 3.5 6.5 31.0 11.9 25.2 13.2 11.1 12.3 8.4 14.1 11.3 12.1 7.8 12.2 9.2 10.8 7.5 8.4 13.7 15.6 8.7 7.5 10.2 17.0 11.8 8.0 6.8 12.3 9.5 9.3 12.6 C1R ENSG00000159403 "Complement C1r" P00736 12 7080209-7092607 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 370.2" "Cell line enhanced" "Detected in many" "ASC diff: 177.7;ASC TERT1: 90.7;BJ hTERT+: 78.2;BJ hTERT+ SV40 Large T+ RasG12V: 48.2;HSkMC: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 2.0;gdT-cell: 1.6;MAIT T-cell: 2.0;memory CD4 T-cell: 1.4;memory CD8 T-cell: 3.4;naive CD4 T-cell: 2.8;naive CD8 T-cell: 2.9;neutrophil: 2.5;NK-cell: 3.2;T-reg: 1.4" "Group enriched" "Detected in many" 6 "granulocytes: 2.5;NK-cells: 3.2;T-cells: 3.4" "Low region specificity" "Detected in all" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol "Secreted to blood" 14000000000 "Nucleoplasm, Cytosol" "HPA001251: , HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavourable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 45.8 17.4 2.6 18.1 3.8 0.0 82.0 1.4 2.8 36.7 24.5 2.4 11.2 5.0 27.2 66.8 38.1 33.3 46.7 49.5 1.9 1.8 27.5 370.2 25.3 46.8 3.5 2.0 103.5 11.4 1.4 6.3 10.3 4.6 47.8 15.3 17.7 12.8 13.2 16.0 10.7 14.4 53.2 6.2 35.1 19.8 39.3 1.9 2.3 30.6 20.7 15.1 46.8 83.8 0.4 0.0 2.5 0.4 3.2 3.4 0.8 0.1 1.5 0.1 1.3 177.7 90.7 0.1 19.9 78.2 23.7 48.2 0.2 0.3 0.0 0.6 15.6 0.2 1.7 0.8 3.3 1.8 0.1 0.0 0.6 0.6 34.2 0.1 0.2 105.0 0.5 10.8 0.8 0.4 0.0 2.5 3.1 0.0 0.8 0.1 0.8 0.1 1.1 0.5 0.1 0.1 0.9 0.0 0.3 14.4 0.4 0.4 0.0 0.0 0.0 5.6 0.9 26.1 0.1 0.1 0.4 0.0 8.1 0.1 0.8 0.0 0.4 2.0 1.6 0.1 2.0 0.0 1.4 3.4 0.0 0.4 2.8 2.9 2.5 3.2 0.0 0.0 1.4 0.8 2.6 3.8 1.4 2.8 1.9 1.8 3.5 2.0 4.6 1.9 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 351.6" "Cell line enhanced" "Detected in some" "ASC diff: 97.0;ASC TERT1: 129.2;BJ hTERT+: 41.1;HSkMC: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 10 "neutrophil: 6.2" "Lineage enriched" "Detected in single" 17 "granulocytes: 6.2" "Low region specificity" "Detected in all" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" 93000000000 13000000000 Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favourable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavourable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 48.7 16.6 3.3 18.7 4.1 0.0 55.7 1.9 3.1 35.3 31.1 2.9 12.7 6.8 32.2 50.0 38.3 46.4 47.2 34.4 2.5 1.1 18.0 351.6 31.4 21.1 6.3 3.2 98.8 15.5 1.9 6.0 8.5 6.5 52.1 18.6 26.1 14.6 12.4 18.2 14.7 19.2 47.6 8.8 32.5 24.6 37.2 2.3 3.2 30.5 22.7 18.8 48.6 73.0 0.2 0.1 6.2 0.3 0.2 0.1 0.0 0.0 2.2 0.1 1.2 97.0 129.2 0.4 17.5 41.1 9.3 17.0 0.0 0.2 0.0 2.4 21.7 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.6 4.6 29.2 0.2 0.1 68.6 0.3 7.5 0.5 0.0 0.0 0.0 1.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.1 10.6 0.2 0.2 0.0 0.0 0.0 4.3 0.3 16.5 0.0 0.0 0.0 0.1 9.3 0.1 0.2 0.6 0.3 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.1 6.2 0.2 0.1 0.1 0.0 0.0 3.3 4.1 1.9 3.1 2.5 1.1 6.3 3.2 6.5 2.3 C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945672 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 132.7" "Group enriched" "Detected in some" 5 "Hep G2: 16.9;Karpas-707: 52.8" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "classical monocyte: 2.9;intermediate monocyte: 6.4;non-classical monocyte: 6.5" "Lineage enriched" "Detected in single" 8 "monocytes: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" CAB016775 Supported "Secreted to blood" 52000000000 "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavourable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" 9.2 3.2 0.9 4.8 1.5 0.8 5.0 1.2 1.3 2.0 5.3 1.8 1.6 2.5 2.0 4.8 1.9 3.3 3.2 5.4 0.8 0.8 13.1 132.7 19.4 13.1 1.2 0.3 2.7 2.1 0.8 2.8 7.6 1.7 1.8 4.3 2.9 2.4 1.5 0.7 1.6 6.6 3.5 1.8 12.1 1.9 2.0 1.0 1.8 1.2 0.8 3.4 2.7 1.5 0.2 0.5 0.8 6.5 0.1 0.3 1.2 0.1 0.0 0.0 0.2 0.0 0.0 0.7 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.6 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 16.9 0.3 0.0 0.2 0.9 0.1 0.2 0.0 0.0 0.1 52.8 0.0 0.0 0.1 0.2 0.1 0.0 0.0 1.3 0.6 0.0 0.0 0.1 0.1 1.0 0.1 0.0 0.1 2.3 0.1 0.1 0.2 0.2 0.0 0.2 6.6 1.0 0.2 0.3 0.0 0.1 2.9 0.0 0.1 6.4 0.1 0.1 0.1 0.1 0.5 0.2 0.3 0.2 0.8 0.1 6.5 0.0 0.1 1.2 0.9 1.5 1.2 1.2 0.8 0.8 1.2 0.3 1.7 1.0 CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217390-27243943 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA057266, HPA069341" Supported Supported Nucleoplasm 26000 Nucleoplasm "CAB007781: AB_562057, HPA057266: AB_2683387, HPA069341: AB_2686125" "unprognostic (1.69e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.71e-3)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavourable (1.72e-11)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "prognostic unfavourable (1.82e-4)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.93e-3)" 12.0 11.9 10.1 23.1 12.4 11.1 18.9 13.3 13.1 14.6 12.4 10.9 9.7 12.1 21.0 18.0 16.3 16.6 15.8 9.8 8.6 8.8 13.1 22.9 13.0 27.9 11.8 9.5 24.4 18.1 10.7 16.4 10.6 10.1 12.5 11.6 12.9 11.7 18.3 12.3 26.0 13.2 17.3 12.5 18.7 11.4 21.3 10.8 35.2 13.8 14.1 18.5 12.7 13.1 5.1 4.9 0.8 2.3 3.7 7.9 2.6 25.2 22.9 10.2 20.4 16.6 13.7 8.1 10.7 7.5 13.6 9.7 25.9 10.1 22.6 9.7 9.8 14.3 30.0 14.2 10.2 14.8 24.2 32.3 17.4 13.5 8.3 25.4 16.3 10.4 11.7 19.7 22.5 14.5 22.7 12.6 11.9 25.4 16.2 37.8 24.5 17.4 28.4 30.6 23.5 10.0 12.9 20.5 10.3 15.0 10.7 12.5 8.3 10.7 13.0 20.6 17.0 16.0 21.5 26.2 16.9 46.2 8.3 24.5 17.7 0.0 1.2 0.5 4.7 2.3 4.0 5.1 6.5 7.7 2.7 5.0 4.3 4.3 0.8 3.7 1.2 4.9 7.9 2.6 10.1 12.4 13.3 13.1 8.6 8.8 11.8 9.5 10.1 10.8 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991717-79009867 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced 2300000 "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavourable (1.41e-4)" "prognostic unfavourable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavourable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 13.8 15.3 9.6 13.1 10.2 8.1 13.0 12.2 10.8 17.7 43.8 12.3 25.4 25.5 12.0 14.3 27.5 10.0 19.5 10.8 9.0 6.9 10.3 17.7 11.1 11.5 12.5 7.7 10.4 14.7 13.1 11.8 33.0 12.0 36.7 41.5 7.9 30.3 41.4 9.0 8.9 27.2 8.0 12.4 18.1 25.8 19.0 10.3 14.1 12.4 8.9 14.4 10.3 13.7 4.1 3.8 17.5 4.4 3.1 6.2 4.4 26.4 29.0 8.1 11.7 7.7 9.2 10.4 16.3 14.3 17.6 14.9 13.7 25.0 6.4 9.6 11.4 13.4 6.9 12.9 17.6 10.6 12.6 8.3 8.8 11.4 6.6 7.9 13.1 9.5 8.3 16.2 8.8 30.3 10.4 10.9 11.7 14.3 12.0 4.7 5.5 30.9 6.7 13.3 7.2 7.7 13.3 11.7 11.7 8.7 57.8 12.3 71.4 9.5 15.1 26.3 23.8 11.8 20.4 12.9 10.7 6.2 16.8 6.1 16.4 6.1 3.8 8.1 6.2 4.4 6.1 4.1 4.6 5.2 3.8 2.9 4.5 4.4 17.5 3.1 2.9 2.7 3.8 4.4 9.6 10.2 12.2 10.8 9.0 6.9 12.5 7.7 12.0 10.3 CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 88.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol 28000000 Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavourable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favourable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" 22.0 15.6 9.6 23.8 11.6 18.2 18.8 17.7 20.1 25.8 33.3 8.4 23.0 25.4 19.3 30.2 86.9 28.1 39.1 21.4 8.8 11.2 27.8 21.3 19.4 19.5 10.8 9.7 21.4 24.9 13.3 14.1 38.1 16.8 27.3 17.0 15.8 39.7 24.3 24.2 38.9 49.9 16.5 7.7 21.3 20.7 8.3 6.7 32.1 37.5 50.2 53.7 33.7 35.2 16.7 22.8 34.5 24.8 15.7 19.6 28.5 47.4 25.3 7.2 16.1 13.2 16.7 22.0 14.1 22.5 16.6 12.7 16.1 42.7 11.9 23.6 26.8 70.2 9.4 59.6 5.3 12.6 7.5 28.3 14.6 15.7 13.1 6.6 39.8 18.4 32.1 14.1 6.9 28.5 16.8 9.6 13.6 30.5 13.1 21.0 20.9 22.9 13.0 7.4 7.2 22.6 88.3 13.0 9.6 14.9 57.7 13.6 24.8 13.1 24.7 13.0 8.9 27.6 6.3 5.9 4.3 14.1 22.6 8.1 14.0 34.3 24.8 34.5 19.6 23.7 15.7 15.6 15.5 17.7 22.8 16.7 9.1 12.5 15.8 15.7 14.0 17.9 16.6 28.5 9.6 11.6 17.7 20.1 8.8 11.2 10.8 9.7 16.8 6.7 CAPN2 "CANPL2, CANPml, mCANP" ENSG00000162909 "Calpain 2" P17655 1 223701593-223776018 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024470 Approved Approved Supported Cytosol 1500000 Cytosol "HPA024470: AB_1845925" "unprognostic (2.77e-2)" "unprognostic (1.27e-3)" "unprognostic (2.03e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (3.32e-2)" "unprognostic (1.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.85e-1)" "unprognostic (1.96e-1)" "prognostic unfavourable (2.50e-4)" "unprognostic (1.21e-1)" "prognostic favourable (2.19e-4)" "unprognostic (1.61e-1)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "prognostic unfavourable (6.21e-4)" 56.2 41.0 23.8 20.7 22.2 11.1 61.1 26.1 20.9 40.3 44.8 18.3 23.3 14.5 29.1 44.5 56.3 40.1 58.9 33.0 26.5 13.1 41.6 13.3 58.6 18.2 27.4 18.2 32.4 26.8 53.7 12.7 26.4 23.8 27.2 44.4 16.5 62.5 31.9 48.1 16.5 22.7 35.7 32.3 15.9 48.2 17.2 24.7 5.0 29.9 39.7 35.9 28.3 38.8 9.0 41.6 1.7 29.1 6.0 28.7 28.2 45.7 29.3 9.4 6.3 31.4 43.6 9.0 43.3 62.9 31.5 17.9 23.2 36.8 0.0 14.3 48.0 28.6 10.1 68.4 29.3 11.7 10.5 0.8 15.0 2.9 28.2 2.4 1.5 23.3 22.2 49.0 26.2 62.4 13.1 12.2 92.6 0.9 0.1 2.1 5.2 38.3 3.8 30.7 0.7 54.3 2.7 2.0 10.9 22.3 60.9 13.5 9.2 11.0 95.9 29.5 24.5 25.4 55.5 3.6 6.9 0.1 73.9 5.1 32.4 1.7 29.1 1.7 28.7 19.5 24.5 9.0 20.0 27.7 41.6 3.6 6.4 17.4 1.5 6.0 17.5 1.9 19.9 28.2 23.8 22.2 26.1 20.9 26.5 13.1 27.4 18.2 23.8 24.7 CAPN3 "CANP3, LGMD2, LGMD2A, nCL-1, p94" ENSG00000092529 "Calpain 3" P20807 15 42359500-42412318 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.6;skeletal muscle: 210.9" "Cell line enriched" "Detected in some" 23 "SK-MEL-30: 75.1" "Cancer enriched" "Detected in some" 10 "melanoma: 9.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040052 Enhanced "HPA040052: " "unprognostic (1.06e-2)" "unprognostic (1.31e-1)" "unprognostic (4.00e-2)" "unprognostic (8.71e-2)" "unprognostic (1.53e-1)" "unprognostic (1.72e-2)" "unprognostic (2.11e-4)" "unprognostic (3.12e-3)" "unprognostic (2.82e-1)" "unprognostic (2.47e-1)" "unprognostic (2.37e-3)" "unprognostic (3.26e-2)" "unprognostic (3.91e-4)" "unprognostic (5.56e-3)" "unprognostic (2.43e-1)" "unprognostic (8.93e-3)" "unprognostic (1.38e-1)" 5.7 1.8 13.0 2.3 32.1 16.7 3.8 3.1 22.9 2.1 2.4 65.6 0.0 2.2 3.1 47.0 4.2 2.5 3.0 3.6 19.9 11.5 22.1 6.3 6.7 3.4 50.7 19.5 3.1 1.4 3.4 1.7 2.0 39.0 3.0 3.2 5.0 3.1 3.1 210.9 19.7 2.3 2.8 52.6 3.3 2.1 4.1 47.3 0.0 1.6 27.6 3.0 2.7 2.3 1.5 1.7 0.9 2.6 1.3 3.2 1.4 0.1 0.2 0.2 0.3 3.2 3.1 0.3 1.2 0.7 0.1 0.2 0.3 0.2 0.0 0.4 0.6 1.8 0.1 1.3 0.1 0.3 0.3 0.2 0.4 1.0 0.1 0.5 0.6 2.1 1.9 0.2 0.5 0.0 0.0 0.9 0.1 0.0 0.0 0.5 0.1 0.2 0.5 0.0 0.7 0.8 0.5 0.0 0.0 0.0 0.1 75.1 0.0 1.7 0.3 0.0 0.1 1.6 0.2 0.4 0.7 0.0 0.2 0.9 0.7 0.0 2.6 0.0 2.8 0.6 2.8 0.4 0.3 1.0 1.7 1.5 0.2 3.2 0.9 1.3 0.2 1.6 1.3 1.4 13.0 32.1 3.1 22.9 19.9 11.5 50.7 19.5 39.0 47.3 CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665734 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 32.0;stomach 1: 85.8" "Cell line enriched" "Detected in some" 9 "RT4: 41.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 28.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD8 T-cell: 1.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: " "unprognostic (4.87e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" "unprognostic (7.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.26e-1)" "unprognostic (8.08e-2)" "unprognostic (2.72e-3)" "unprognostic (3.55e-1)" "unprognostic (4.12e-6)" "unprognostic (6.95e-2)" "unprognostic (5.59e-2)" "unprognostic (3.83e-2)" "unprognostic (5.44e-3)" 0.2 0.0 0.5 10.3 0.3 0.0 7.5 0.2 0.3 1.0 7.9 0.6 0.2 2.2 0.3 3.3 0.6 0.4 32.0 0.2 0.2 0.1 2.5 0.2 13.0 0.2 0.2 0.2 0.2 8.0 0.0 0.2 0.8 0.2 4.6 9.9 0.2 4.6 0.3 0.3 1.5 4.0 3.2 0.2 0.2 85.8 0.4 0.2 0.3 0.2 1.5 1.2 15.1 3.9 0.4 0.0 1.1 0.0 0.0 1.4 1.5 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 2.4 0.0 0.0 0.0 4.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.9 41.1 0.6 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.9 0.7 0.0 0.0 0.1 1.4 1.1 0.0 0.0 0.0 0.0 1.5 0.5 0.3 0.2 0.3 0.2 0.1 0.2 0.2 0.2 0.2 CASP1 "ICE, IL1BC" ENSG00000137752 "Caspase 1" P29466 11 105025443-105035250 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 64.2;lymphoid tissue: 40.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 37.8;HBEC3-KT: 17.9;HHSteC: 20.3;U-937: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Region enhanced" "Detected in many" "olfactory region: 22.8" "Low region specificity" "Detected in all" "CAB002685, HPA003056" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB002685: , HPA003056: AB_1846037" "unprognostic (1.21e-3)" "unprognostic (3.02e-1)" "unprognostic (9.47e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (6.67e-2)" "unprognostic (2.75e-2)" "unprognostic (1.35e-1)" "prognostic unfavourable (3.11e-4)" "unprognostic (9.03e-2)" "unprognostic (2.30e-2)" "unprognostic (3.18e-1)" "unprognostic (5.19e-2)" 7.4 3.9 6.6 15.1 17.0 8.2 6.9 3.5 7.0 4.1 12.8 2.2 2.9 34.0 3.0 4.2 10.6 4.3 7.3 4.9 9.3 3.0 6.4 5.8 20.5 16.2 16.7 2.6 4.4 3.4 0.2 3.7 8.7 13.3 6.1 13.9 3.7 7.0 3.2 1.6 9.9 37.2 5.2 17.4 40.7 5.6 1.5 11.0 4.1 3.7 5.6 9.0 9.7 13.2 7.3 39.6 40.5 64.2 11.1 34.3 31.2 0.4 0.1 0.0 1.8 2.0 4.2 0.3 1.9 37.8 4.8 13.2 0.0 0.2 6.1 0.7 2.1 2.7 0.0 17.9 1.1 4.0 0.0 0.3 0.2 0.4 20.3 7.1 0.0 7.2 12.7 3.9 10.4 2.0 0.0 0.0 1.1 0.0 0.2 9.9 0.0 0.1 5.9 0.1 4.8 0.1 2.9 0.1 0.1 5.6 0.3 8.3 0.4 16.4 2.4 4.4 0.2 0.4 0.5 0.0 1.7 0.0 2.7 44.7 0.9 12.3 42.8 23.2 25.4 64.2 34.3 7.3 18.1 22.0 39.6 6.0 9.9 16.4 40.5 11.1 64.0 1.4 22.2 31.2 6.6 17.0 3.5 7.0 9.3 3.0 16.7 2.6 13.3 11.0 CASP10 MCH4 ENSG00000003400 "Caspase 10" Q92851 2 201182881-201229406 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 42.4" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 17.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003780, HPA017059" Approved Approved "Golgi apparatus,Vesicles" "Golgi apparatus" Vesicles "CAB003780: AB_289592, HPA017059: AB_1846040" "unprognostic (4.01e-2)" "unprognostic (8.24e-2)" "unprognostic (4.80e-1)" "unprognostic (1.28e-3)" "unprognostic (4.74e-2)" "unprognostic (2.25e-1)" "prognostic unfavourable (8.54e-4)" "unprognostic (1.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.68e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" "prognostic unfavourable (6.05e-7)" "unprognostic (3.23e-2)" "unprognostic (2.19e-2)" "unprognostic (4.49e-2)" "unprognostic (1.38e-2)" 16.0 3.3 3.4 10.1 3.4 14.9 7.6 1.9 3.3 7.0 17.7 4.4 4.3 18.6 8.3 8.2 10.4 4.9 7.2 4.8 3.6 3.0 10.3 7.8 14.2 10.4 4.1 1.4 3.4 6.1 1.4 2.1 8.5 4.7 5.0 11.9 4.1 6.9 6.9 3.6 5.4 42.4 4.8 5.6 26.1 8.7 2.1 2.5 17.1 6.8 8.2 17.9 9.4 6.1 7.8 6.0 4.7 15.4 7.1 7.1 5.8 2.9 2.3 0.1 0.2 0.1 0.2 5.1 0.5 3.4 0.3 1.3 3.1 6.8 0.2 4.9 1.7 1.9 0.1 1.6 0.9 1.4 3.3 8.2 2.4 10.2 1.1 5.4 8.9 0.3 1.4 3.7 0.3 17.7 9.8 12.1 0.3 0.1 10.5 5.1 0.3 1.5 5.7 0.3 12.1 6.2 4.1 0.1 0.1 2.8 0.1 1.3 0.0 5.2 7.1 0.2 0.5 2.3 0.1 13.2 7.8 0.3 3.3 4.2 0.1 4.7 9.6 0.6 6.2 13.5 5.2 7.8 5.2 3.4 5.3 5.0 7.1 6.0 1.9 7.1 15.4 6.0 1.0 5.8 3.4 3.4 1.9 3.3 3.6 3.0 4.1 1.4 4.7 2.5 CASP2 "ICH1, MGC2181, NEDD2, PPP1R57" ENSG00000106144 "Caspase 2" P42575 7 143288215-143307696 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012175, HPA050678" Approved Approved Nucleoplasm Nucleoplasm "CAB012175: , HPA050678: " "unprognostic (6.96e-2)" "prognostic favourable (7.38e-4)" "unprognostic (2.74e-2)" "unprognostic (7.51e-2)" "unprognostic (4.24e-2)" "unprognostic (2.39e-2)" "prognostic unfavourable (2.34e-4)" "unprognostic (1.74e-2)" "unprognostic (1.34e-2)" "prognostic favourable (2.89e-4)" "unprognostic (1.91e-2)" "unprognostic (1.64e-1)" "prognostic unfavourable (5.01e-6)" "unprognostic (2.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-1)" "unprognostic (1.64e-1)" 10.5 6.5 6.6 10.7 6.7 26.8 10.2 9.6 10.9 9.6 8.5 9.0 8.2 8.2 10.8 7.8 14.1 8.4 5.7 6.1 5.7 4.1 7.3 5.8 9.8 15.8 6.9 6.1 8.7 8.1 12.1 6.6 11.3 7.3 7.6 10.2 10.1 11.6 5.8 4.3 14.2 14.0 7.4 6.3 18.6 7.5 8.6 6.9 45.7 8.9 8.0 23.0 7.4 10.2 18.5 11.8 33.2 17.7 13.4 21.4 7.6 10.7 10.1 11.4 20.2 6.4 7.6 6.1 11.1 5.0 10.2 11.2 10.1 12.3 20.5 10.5 7.0 10.6 11.4 8.7 13.6 17.9 8.8 12.1 16.0 6.9 3.4 23.6 15.2 5.2 7.2 12.3 4.4 8.7 10.1 13.1 10.8 10.6 41.0 24.9 14.3 10.3 30.2 5.9 12.5 6.0 9.2 12.5 14.1 22.0 9.6 7.0 10.5 9.0 9.7 9.0 6.3 16.2 11.0 10.9 10.7 23.8 10.2 28.1 16.4 33.2 10.8 9.3 14.9 11.9 14.6 15.8 20.6 15.4 9.8 18.5 15.4 17.8 12.3 13.4 17.7 11.8 21.4 7.6 6.6 6.7 9.6 10.9 5.7 4.1 6.9 6.1 7.3 6.9 CASP3 "apopain, CPP32, CPP32B, Yama" ENSG00000164305 "Caspase 3" P42574 4 184627696-184649509 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 76.7" "Cell line enhanced" "Detected in all" "Karpas-707: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 76.7;eosinophil: 62.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000091, HPA002643, CAB008381" Enhanced Supported Nucleoplasm,Mitochondria 310000 "Nucleoplasm, Mitochondria" "CAB000091: , CAB008381: AB_590737, HPA002643: AB_1846048" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "prognostic favourable (2.24e-4)" "unprognostic (2.29e-3)" "unprognostic (3.58e-2)" "unprognostic (9.57e-3)" "unprognostic (5.86e-2)" "unprognostic (3.56e-2)" "unprognostic (1.12e-2)" "unprognostic (1.70e-2)" "unprognostic (2.41e-1)" "prognostic unfavourable (2.30e-5)" "unprognostic (1.41e-2)" "unprognostic (5.74e-3)" "unprognostic (1.30e-1)" "unprognostic (4.05e-3)" 20.7 11.6 10.8 16.9 10.5 16.7 10.0 22.3 9.2 10.4 25.4 12.8 12.5 32.3 13.9 11.5 22.8 8.9 12.0 8.8 10.0 8.8 10.6 18.7 12.4 23.6 10.2 8.5 8.3 10.0 4.6 13.6 29.4 9.7 8.8 20.9 8.2 13.0 10.0 12.6 9.5 49.7 9.3 12.6 26.5 18.7 6.4 10.9 44.7 7.8 13.5 24.3 16.2 11.0 4.2 5.2 76.7 10.6 9.2 9.9 7.0 8.2 4.6 18.3 8.7 11.4 15.2 10.6 24.8 18.8 17.4 10.1 8.3 6.9 11.5 3.9 12.1 7.0 14.5 8.8 19.9 29.4 7.9 18.3 3.6 19.3 13.6 14.9 17.5 20.7 10.8 11.0 9.0 21.5 15.1 72.7 17.9 3.5 23.5 13.9 18.1 5.8 17.0 8.6 11.0 15.0 13.5 10.5 11.4 10.7 9.8 13.9 5.3 9.7 14.6 8.0 7.3 5.9 11.4 33.8 31.7 7.9 9.7 10.4 11.3 76.7 4.2 62.8 5.5 6.8 5.7 4.2 5.1 7.8 5.2 3.1 3.9 5.8 5.8 9.2 10.6 4.1 9.9 7.0 10.8 10.5 22.3 9.2 10.0 8.8 10.2 8.5 9.7 10.9 CASP4 "ICE(rel)II, ICH-2, TX" ENSG00000196954 "Caspase 4" P49662 11 104942866-104969436 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "blood: 82.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA027588, CAB037167" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Cytosol "Plasma membrane" "CAB037167: AB_258864, HPA027588: AB_10603781" "unprognostic (1.19e-2)" "unprognostic (3.73e-1)" "unprognostic (3.44e-1)" "unprognostic (1.99e-2)" "unprognostic (7.19e-3)" "unprognostic (2.63e-2)" "unprognostic (1.26e-2)" "unprognostic (1.56e-2)" "unprognostic (5.31e-2)" "unprognostic (2.71e-1)" "unprognostic (2.38e-3)" "unprognostic (8.39e-3)" "prognostic unfavourable (3.27e-11)" "unprognostic (6.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-2)" "unprognostic (4.08e-3)" 10.6 6.3 0.5 9.7 0.5 6.1 9.4 0.0 0.0 4.7 3.5 8.9 3.5 5.9 14.1 5.8 7.3 4.9 0.5 0.5 6.7 16.5 14.0 10.5 1.0 7.5 16.8 0.0 3.0 10.7 5.8 4.0 11.2 1.9 1.6 10.4 8.8 4.3 2.0 19.0 8.2 0.2 4.2 11.3 8.2 8.0 20.5 29.3 82.8 43.2 29.6 35.7 46.8 6.3 2.1 0.0 2.8 13.7 31.2 5.3 11.0 21.5 17.7 24.8 5.3 29.0 3.3 23.7 14.2 10.6 0.0 19.0 16.9 3.7 0.1 8.6 1.6 13.8 33.6 8.6 4.2 28.3 28.5 21.1 29.5 30.7 0.2 0.0 13.5 0.6 5.0 10.2 0.0 6.3 3.8 4.1 2.9 14.8 10.1 0.1 0.0 10.1 7.2 10.0 2.9 12.6 15.9 18.7 6.5 16.4 7.7 0.0 0.0 0.0 9.5 19.7 13.0 14.9 39.1 7.0 31.5 43.2 34.6 20.5 24.2 30.1 29.3 20.0 14.8 22.0 82.8 29.6 33.5 4.9 35.7 46.8 CASP5 ICE(rel)III ENSG00000137757 "Caspase 5" P51878 11 104994235-105023168 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood: 22.3;intestine: 31.0;lymphoid tissue: 12.3" "Cell line enriched" "Detected in some" 7 "HHSteC: 9.1" "Group enriched" "Detected in some" 7 "colorectal cancer: 3.9;stomach cancer: 1.3" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 13 "intermediate monocyte: 10.5;neutrophil: 7.8;non-classical monocyte: 22.3" "Group enriched" "Detected in many" 14 "granulocytes: 7.8;monocytes: 22.3" "unprognostic (4.30e-2)" "unprognostic (8.86e-2)" "unprognostic (1.07e-1)" "unprognostic (4.74e-2)" "unprognostic (1.66e-1)" "unprognostic (5.22e-2)" "unprognostic (9.90e-2)" "unprognostic (8.29e-3)" "unprognostic (1.47e-1)" "unprognostic (4.38e-3)" "unprognostic (7.39e-3)" "unprognostic (3.25e-1)" "unprognostic (1.82e-9)" "unprognostic (7.30e-2)" "unprognostic (2.67e-3)" "unprognostic (1.87e-1)" "unprognostic (1.50e-1)" 0.6 0.3 0.3 11.8 1.0 0.0 0.3 0.2 0.8 0.2 13.3 0.2 0.0 8.2 0.2 0.2 0.3 0.5 0.1 0.4 2.9 0.3 0.4 1.2 2.7 10.5 0.4 0.2 0.2 0.3 0.0 0.9 0.5 2.0 0.4 11.3 0.2 0.3 0.0 0.8 0.2 31.0 1.4 2.1 12.3 0.4 0.3 0.3 0.3 0.3 0.3 0.1 0.9 0.3 0.0 1.0 7.8 22.3 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.8 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 9.1 0.0 0.0 0.3 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 10.5 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.8 0.0 22.3 0.3 0.0 0.6 0.3 1.0 0.2 0.8 2.9 0.3 0.4 0.2 2.0 0.3 CASP6 MCH2 ENSG00000138794 "Caspase 6" P55212 4 109688622-109703583 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 42.8" "Cell line enhanced" "Detected in all" "Karpas-707: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003775, HPA011337, HPA024303" Enhanced Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB003775: AB_562064, HPA011337: AB_1846053, HPA024303: AB_1846052" "unprognostic (1.07e-1)" "unprognostic (1.91e-1)" "prognostic favourable (2.64e-5)" "unprognostic (1.45e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "unprognostic (3.03e-3)" "unprognostic (9.87e-2)" "unprognostic (2.73e-2)" "unprognostic (2.59e-3)" "unprognostic (1.15e-2)" "unprognostic (6.78e-2)" "unprognostic (2.44e-1)" "unprognostic (8.74e-3)" "unprognostic (2.18e-1)" "unprognostic (2.41e-1)" "prognostic favourable (9.93e-4)" 8.1 6.1 3.6 6.7 4.3 5.3 14.3 2.8 3.8 6.9 25.5 2.8 4.5 23.4 5.9 4.3 8.7 5.3 11.7 4.9 4.0 2.0 11.0 14.3 5.6 8.5 5.0 1.6 7.0 13.0 2.3 6.4 4.3 4.5 8.1 19.5 3.4 8.0 10.3 3.4 6.5 42.8 14.0 6.6 9.1 9.2 2.7 4.3 14.5 11.2 3.3 8.4 8.2 12.7 4.4 8.0 8.5 7.0 5.6 21.3 8.0 12.4 4.0 8.3 7.5 6.1 6.0 12.3 7.0 4.8 6.2 6.8 6.7 25.6 1.3 8.1 7.1 5.8 9.9 11.0 5.0 19.7 6.5 10.9 3.6 5.9 4.9 10.9 7.7 6.6 8.2 6.0 1.5 11.8 14.1 38.8 10.1 7.0 28.1 6.9 6.3 7.3 9.8 5.3 6.8 20.6 11.8 8.8 6.6 7.4 13.3 4.1 5.7 4.0 10.0 6.9 7.4 3.3 7.9 5.7 10.3 1.4 9.0 13.1 3.5 8.5 5.3 6.3 4.9 4.8 5.3 4.1 17.8 9.3 6.0 4.4 21.3 11.8 1.1 5.6 7.0 8.0 16.4 8.0 3.6 4.3 2.8 3.8 4.0 2.0 5.0 1.6 4.5 4.3 CASP7 "CMH-1, ICE-LAP3, MCH3" ENSG00000165806 "Caspase 7" P55210 10 113679162-113730907 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 64.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB025563 Approved "CAB025563: " "prognostic favourable (2.11e-4)" "unprognostic (3.18e-2)" "unprognostic (2.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-3)" "unprognostic (3.96e-1)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "prognostic unfavourable (5.90e-4)" "unprognostic (5.45e-3)" "unprognostic (2.62e-1)" "unprognostic (2.86e-1)" "unprognostic (4.33e-3)" 16.5 7.8 8.6 12.3 8.7 3.4 22.1 4.7 11.3 13.3 35.5 5.9 9.8 30.8 12.6 6.1 12.0 9.5 7.8 9.0 7.6 3.9 14.1 15.7 16.2 12.2 7.3 2.7 11.0 18.4 5.7 9.6 10.2 9.1 11.9 28.5 5.8 21.8 10.5 9.7 10.9 64.8 9.3 12.4 12.3 21.0 4.3 8.0 12.0 8.4 8.1 11.3 10.6 36.6 9.6 8.6 14.6 17.1 5.4 12.2 7.4 10.8 11.7 9.6 5.1 17.6 15.5 6.7 12.6 19.7 22.5 28.3 8.7 18.8 11.5 7.5 11.4 9.6 11.8 9.5 16.0 17.8 15.9 7.4 8.7 14.5 11.8 7.9 9.8 10.0 6.4 12.8 5.3 29.7 1.9 15.7 8.3 14.6 18.7 6.2 1.7 7.2 19.1 39.1 6.9 17.8 8.0 0.7 5.7 9.7 14.1 6.6 16.7 7.0 14.2 5.0 9.6 5.2 10.3 11.6 7.3 0.3 5.1 14.9 5.6 14.6 12.5 9.4 9.6 17.1 8.4 9.6 8.3 12.2 8.6 7.3 6.5 8.7 2.1 5.4 14.0 1.1 11.1 7.4 8.6 8.7 4.7 11.3 7.6 3.9 7.3 2.7 9.1 8.0 CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201287711 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 52.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001302, CAB002047, HPA005688, HPA006191" Approved Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: " "unprognostic (5.21e-3)" "unprognostic (2.10e-1)" "unprognostic (1.83e-2)" "unprognostic (9.69e-3)" "unprognostic (2.09e-1)" "unprognostic (5.60e-2)" "prognostic unfavourable (3.02e-4)" "unprognostic (2.10e-1)" "unprognostic (4.79e-2)" "prognostic favourable (1.25e-4)" "unprognostic (7.75e-2)" "unprognostic (5.11e-2)" "prognostic unfavourable (1.27e-6)" "unprognostic (7.67e-3)" "unprognostic (2.43e-1)" "unprognostic (2.53e-1)" "unprognostic (4.53e-3)" 14.1 10.6 2.0 31.6 2.6 27.1 10.2 1.4 1.8 7.9 18.5 3.9 7.0 9.6 9.6 12.0 11.7 9.1 12.1 4.4 2.1 2.3 16.4 14.8 17.1 28.3 3.9 1.1 8.2 7.6 1.8 5.9 12.3 3.2 9.8 8.7 4.4 9.6 8.4 2.7 7.4 34.7 5.1 5.0 37.7 7.4 3.8 2.7 43.7 6.7 10.7 43.4 9.6 7.3 13.8 13.7 52.5 17.0 22.2 26.4 12.0 14.3 12.2 3.6 9.9 10.0 14.6 5.5 6.3 6.2 7.5 12.4 16.4 25.0 1.6 13.9 4.9 7.3 7.8 7.5 14.8 9.3 7.1 14.0 9.9 15.6 8.1 10.8 15.2 12.7 18.5 14.2 11.1 7.1 12.5 31.2 6.8 5.9 14.1 11.5 5.8 10.9 10.6 7.4 25.5 14.1 16.0 1.0 0.5 8.2 13.6 8.1 3.6 8.5 8.8 8.1 8.4 4.2 4.9 28.3 12.6 9.7 12.2 14.6 7.6 20.7 13.0 24.9 25.0 17.0 23.1 13.8 20.5 26.4 13.7 7.8 13.3 16.9 52.5 22.2 15.6 6.1 24.0 12.0 2.0 2.6 1.4 1.8 2.1 2.3 3.9 1.1 3.2 2.7 CASP9 "APAF-3, ICE-LAP6, MCH6, PPP1R56" ENSG00000132906 "Caspase 9" P55211 1 15490832-15526534 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001473, CAB004348, HPA046488" Approved Approved Mitochondria Mitochondria "CAB004348: AB_673489, HPA001473: AB_1078401, HPA046488: " "prognostic favourable (5.91e-4)" "unprognostic (2.42e-1)" "unprognostic (8.94e-3)" "unprognostic (7.84e-2)" "unprognostic (1.93e-2)" "unprognostic (8.54e-3)" "unprognostic (1.90e-3)" "unprognostic (6.75e-2)" "unprognostic (2.58e-1)" "unprognostic (1.29e-1)" "unprognostic (9.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.39e-2)" "unprognostic (2.35e-1)" "unprognostic (3.21e-2)" "unprognostic (5.48e-2)" "prognostic favourable (1.67e-5)" 7.4 24.1 7.8 8.2 9.3 8.9 5.5 11.1 8.7 8.3 9.3 10.2 18.9 5.2 11.9 16.5 7.5 13.4 29.1 10.2 8.3 7.2 11.6 9.4 10.8 12.6 10.7 4.3 33.4 29.0 15.6 18.5 14.7 8.8 10.2 6.4 8.7 6.6 19.0 8.2 2.8 13.3 7.8 9.0 11.0 6.7 14.4 7.1 6.2 14.8 7.2 14.6 7.3 8.1 11.2 11.7 23.3 11.2 13.0 5.1 6.1 7.1 10.4 4.1 7.1 9.3 4.6 3.7 5.2 6.9 7.8 10.0 7.3 8.6 10.4 12.3 7.1 2.5 6.8 5.5 9.0 3.6 8.5 7.4 23.2 7.3 8.7 7.2 8.7 6.3 10.2 11.9 3.6 8.3 16.7 9.7 4.6 3.6 2.4 8.2 4.0 5.8 4.8 10.2 12.1 9.6 4.1 3.5 6.8 7.4 1.8 12.3 4.4 5.2 3.3 10.4 4.8 11.2 3.4 9.4 14.1 11.7 7.9 7.8 3.4 22.7 11.2 23.3 5.1 8.2 3.7 9.6 3.0 3.6 11.7 11.2 1.7 2.6 16.0 13.0 7.9 5.2 2.8 6.1 7.8 9.3 11.1 8.7 8.3 7.2 10.7 4.3 8.8 7.1 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853230 "Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 94.9;seminal vesicle: 104.1" "Cell line enhanced" "Detected in some" "Daudi: 49.8;Karpas-707: 13.9;MOLT-4: 12.6;REH: 10.0;U-266/70: 10.8;U-698: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cell: 15.3" "Group enriched" "Detected in all" 4 "B-cells: 9.0;dendritic cells: 5.1;NK-cells: 15.3" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favourable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 4.1 3.3 3.8 17.6 8.5 9.3 2.6 0.7 12.0 1.0 3.2 10.4 14.6 4.3 0.7 0.9 2.3 2.4 1.5 5.0 4.0 4.2 1.2 5.4 4.7 16.1 4.9 3.1 0.6 0.7 0.0 2.5 0.6 3.1 10.8 2.7 4.4 2.8 104.1 14.2 0.5 6.2 0.9 1.8 20.6 2.0 0.7 2.5 94.9 2.8 2.0 13.2 7.6 0.9 9.0 5.1 1.3 2.2 15.3 2.3 3.7 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 49.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 13.9 0.0 0.0 12.6 3.0 0.0 0.0 10.0 0.0 7.8 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 2.2 0.2 0.0 0.0 0.0 0.0 10.8 0.1 9.4 0.1 2.4 0.1 0.0 1.7 0.0 1.1 2.2 0.3 9.0 1.4 1.2 4.1 6.6 2.3 1.8 1.3 15.3 1.4 5.1 2.1 3.7 3.8 8.5 0.7 6.2 4.0 4.2 4.9 3.1 3.1 2.5 CDA CDD ENSG00000158825 "Cytidine deaminase" P32320 1 20588948-20618908 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 126.5;bone marrow: 68.0" "Cell line enhanced" "Detected in many" "A-431: 41.9;CAPAN-2: 28.0;HeLa: 39.7;PC-3: 20.0;SiHa: 49.8;U-937: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 126.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 126.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA064202 Enhanced Approved Nucleoplasm 3700000 Nucleoplasm "HPA064202: " "unprognostic (2.38e-1)" "prognostic unfavourable (5.05e-4)" "unprognostic (2.86e-1)" "unprognostic (2.56e-1)" "unprognostic (8.02e-2)" "unprognostic (3.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.68e-3)" "unprognostic (2.64e-1)" "unprognostic (4.01e-2)" "prognostic unfavourable (8.56e-5)" "unprognostic (2.94e-2)" "unprognostic (5.03e-2)" "unprognostic (8.47e-3)" "unprognostic (2.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.89e-3)" 4.0 1.4 1.5 4.0 1.5 68.0 2.2 1.1 2.4 19.0 8.6 1.7 2.0 2.6 6.7 3.5 38.3 2.9 1.8 5.9 1.7 1.6 12.5 42.1 8.4 9.1 2.0 1.3 2.9 0.8 1.2 0.7 30.8 3.5 4.2 10.2 4.5 6.9 1.5 3.2 7.0 24.7 4.3 1.9 11.8 1.2 2.9 0.9 0.9 3.0 23.3 10.5 3.1 16.5 0.0 1.3 126.5 21.7 0.0 0.1 7.1 41.9 4.1 0.0 0.0 0.0 1.2 0.0 3.2 0.8 0.8 3.3 0.2 28.0 0.0 1.6 6.7 14.7 0.8 11.0 2.2 0.0 0.8 0.0 39.7 5.3 0.3 0.0 0.0 1.8 1.8 7.9 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 20.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 49.8 0.0 0.0 0.0 1.2 0.7 0.0 1.7 3.8 0.2 0.0 0.0 0.0 0.5 17.6 0.0 16.3 21.7 43.3 0.0 11.4 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 126.5 0.0 9.3 0.2 0.0 7.1 1.5 1.5 1.1 2.4 1.7 1.6 2.0 1.3 3.5 0.9 CDC14A "cdc14, Cdc14A1, Cdc14A2, DFNB105" ENSG00000079335 "Cell division cycle 14A" Q9UNH5 1 100345001-100520278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Hearing" "Hydrolase, Protein phosphatase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.2" "Cell line enhanced" "Detected in many" "K-562: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023783 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" Nucleoplasm "Nuclear bodies, Cytosol" "HPA023783: AB_1846352" "unprognostic (3.72e-2)" "unprognostic (2.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-2)" "unprognostic (1.54e-3)" "unprognostic (1.38e-1)" "unprognostic (9.27e-4)" "unprognostic (4.88e-3)" "unprognostic (6.30e-2)" "unprognostic (3.97e-3)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-3)" "unprognostic (6.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.49e-2)" "unprognostic (6.66e-2)" 6.2 2.4 5.8 6.5 5.5 13.7 12.2 1.8 6.2 7.7 11.8 4.8 2.2 7.2 15.1 4.8 3.4 13.7 3.6 4.1 8.8 3.5 6.6 2.4 12.3 15.4 3.8 5.4 5.8 6.7 9.8 8.1 7.6 4.6 10.0 6.3 8.3 7.7 3.9 4.3 5.6 22.6 5.0 3.2 9.6 6.0 38.2 4.7 12.0 6.1 3.4 11.3 5.8 8.4 4.8 6.1 11.6 3.7 3.9 13.0 4.1 2.2 1.8 5.8 6.5 2.1 1.6 4.0 2.8 1.9 2.8 2.3 6.1 1.9 1.1 2.1 1.7 1.7 3.9 1.6 2.9 2.2 9.7 3.9 1.7 1.9 0.8 5.2 7.0 1.3 0.4 3.0 1.0 4.9 30.0 3.4 4.1 0.9 4.2 5.9 3.5 2.3 4.6 7.5 1.1 1.9 5.0 1.0 1.8 3.0 2.9 3.9 1.3 6.8 2.1 1.6 3.5 2.6 1.6 1.7 0.6 1.7 1.9 4.9 0.9 11.6 3.7 8.4 7.3 3.3 13.0 4.8 11.3 8.4 3.5 3.1 11.0 5.8 5.5 3.9 2.3 6.1 5.6 4.1 5.8 5.5 1.8 6.2 8.8 3.5 3.8 5.4 4.6 4.7 CDC14B "Cdc14B1, Cdc14B2, CDC14B3, hCDC14B" ENSG00000081377 "Cell division cycle 14B" O60729 9 96490241-96619830 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 15.1;ASC TERT1: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 9.9" "Lineage enhanced" "Detected in many" "granulocytes: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013312, HPA064747" Approved Supported Nucleoplasm Nucleoplasm "HPA013312: AB_1846354, HPA064747: " "unprognostic (5.69e-2)" "unprognostic (9.09e-2)" "unprognostic (3.50e-2)" "unprognostic (8.08e-3)" "unprognostic (4.24e-1)" "unprognostic (1.19e-2)" "unprognostic (1.11e-2)" "unprognostic (4.49e-2)" "unprognostic (1.63e-2)" "unprognostic (2.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.75e-1)" "prognostic favourable (2.97e-10)" "unprognostic (2.01e-2)" "unprognostic (2.61e-1)" "prognostic unfavourable (2.82e-4)" "unprognostic (7.40e-2)" 7.3 6.2 6.8 3.0 7.5 4.4 15.7 2.4 6.6 5.3 5.0 14.8 7.1 4.5 4.0 3.7 3.5 7.1 5.9 8.2 6.0 4.6 9.1 16.0 4.9 1.8 9.5 4.0 5.8 7.3 17.1 5.2 3.4 7.1 5.7 5.4 8.3 3.8 7.2 2.2 3.3 7.7 4.2 9.3 2.2 9.3 16.9 8.2 0.2 13.6 2.2 2.1 10.4 10.3 1.6 0.0 9.9 0.0 0.1 2.9 0.8 5.1 2.9 3.1 3.2 15.1 22.7 8.5 3.8 5.0 2.5 4.1 9.9 8.3 0.0 3.7 8.0 5.8 4.4 3.0 3.0 1.3 4.1 0.8 1.0 7.7 2.4 0.0 0.1 9.3 1.5 2.7 2.5 0.5 3.0 0.6 3.5 2.5 0.0 0.8 5.8 2.5 0.0 1.9 0.1 4.0 8.0 0.9 4.9 2.6 0.8 1.5 0.7 1.7 1.5 2.5 3.0 6.5 2.7 0.1 0.0 0.0 2.7 0.0 6.0 9.9 0.0 3.1 2.9 0.0 1.6 1.6 1.3 2.3 0.0 0.8 2.3 1.4 0.0 0.1 0.0 0.0 1.6 0.8 6.8 7.5 2.4 6.6 6.0 4.6 9.5 4.0 7.1 8.2 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188402 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 23.0;testis: 19.4" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 1.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005855 Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA005855: AB_1846364" "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.8 1.2 1.1 5.5 1.1 13.0 0.8 0.7 1.2 1.1 3.3 0.6 1.0 1.8 0.6 0.9 3.9 0.4 2.2 0.7 1.3 2.4 1.2 0.9 0.7 4.1 1.4 0.2 2.1 3.6 0.4 2.3 4.2 1.2 1.0 4.0 1.5 1.8 0.5 0.7 0.8 2.1 0.8 0.7 3.6 1.3 19.4 0.2 23.0 1.6 8.8 7.4 0.8 1.3 1.7 0.9 0.5 0.1 0.0 1.0 0.1 7.5 3.7 17.8 9.6 0.6 1.2 12.3 10.5 4.0 13.2 10.7 16.1 3.9 22.4 4.1 2.7 5.7 30.5 7.2 13.9 7.3 16.0 28.7 6.8 7.9 0.6 20.2 8.3 0.6 1.1 16.4 7.1 5.0 22.8 11.9 7.1 4.0 25.2 15.7 26.0 8.5 11.3 11.7 12.2 3.3 7.1 8.4 10.4 6.5 7.6 3.3 4.0 14.3 2.5 6.5 10.0 7.2 14.2 6.0 17.9 35.2 4.8 22.5 5.4 0.0 0.0 0.5 0.4 0.0 0.0 1.7 0.6 0.2 0.9 0.0 0.0 1.0 0.0 0.0 0.1 0.5 0.0 0.1 1.1 1.1 0.7 1.2 1.3 2.4 1.4 0.2 1.2 0.2 CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 4.5;NK-cells: 9.3;T-cells: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Supported "Vesicles,Mitotic spindle" Vesicles "Mitotic spindle" "HPA038892: , HPA038893: , HPA075215: " "unprognostic (4.69e-2)" "unprognostic (5.74e-2)" "unprognostic (2.93e-2)" "prognostic unfavourable (4.76e-4)" "unprognostic (1.13e-1)" "unprognostic (4.23e-1)" "prognostic unfavourable (1.19e-4)" "unprognostic (1.31e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "prognostic unfavourable (2.94e-13)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (3.94e-1)" "unprognostic (9.46e-2)" 12.1 8.7 15.1 27.7 23.3 26.0 28.8 49.6 21.1 13.0 14.7 12.8 4.6 14.9 17.0 10.3 11.7 13.0 18.6 7.5 15.7 12.5 13.3 11.0 33.0 42.8 21.9 12.5 17.3 5.7 7.5 21.0 30.3 13.8 11.0 12.0 7.7 7.4 10.2 6.2 19.8 16.8 14.8 14.7 24.5 14.1 6.3 22.3 33.3 18.7 20.8 31.6 15.3 16.3 4.5 1.3 1.5 1.8 9.3 15.5 5.9 29.8 64.5 8.6 14.3 10.6 10.4 4.3 14.8 22.2 24.8 18.5 11.2 43.3 20.8 6.4 15.1 43.7 11.7 24.6 11.7 8.0 12.6 11.2 20.7 13.5 42.3 8.7 5.8 10.2 19.8 23.0 27.2 13.7 7.2 55.1 14.6 24.0 27.1 12.7 6.4 27.6 14.2 24.4 14.9 16.9 2.8 6.2 13.5 35.1 33.5 17.2 11.3 4.5 11.3 13.3 16.1 24.1 19.6 13.4 21.2 8.4 6.8 8.6 12.8 1.5 1.4 0.0 13.6 1.8 12.7 3.5 13.6 13.7 1.3 4.5 11.4 13.2 0.1 9.3 0.9 0.7 15.5 5.9 15.1 23.3 49.6 21.1 15.7 12.5 21.9 12.5 13.8 22.3 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285265-138338355 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 23.3;testis: 22.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.1;T-reg: 2.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB003800, HPA066991" Approved Supported "Nuclear speckles" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: " "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favourable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavourable (3.03e-6)" "prognostic unfavourable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 1.1 0.6 0.3 6.7 0.4 5.2 1.1 0.4 0.6 0.6 3.3 0.1 0.7 3.0 0.3 0.6 2.5 0.2 0.4 0.7 0.4 0.4 0.4 0.6 0.7 2.6 0.4 0.3 0.3 0.3 0.0 0.4 1.9 0.3 0.4 4.0 0.0 1.2 0.7 0.2 1.1 3.7 0.5 0.3 1.7 1.2 22.3 0.2 23.3 0.3 1.8 5.0 0.6 0.9 1.0 0.1 0.7 0.0 2.1 2.7 0.5 13.5 5.6 19.0 14.6 0.4 1.9 4.8 8.1 8.8 18.6 25.7 13.6 26.3 6.3 6.9 4.9 7.3 15.6 12.5 18.0 5.2 10.7 4.8 7.7 10.1 0.1 3.2 4.9 0.4 0.5 11.0 9.0 11.9 7.0 12.4 11.3 7.4 8.8 8.1 4.9 6.2 5.8 17.3 7.3 3.2 4.1 9.6 5.9 18.3 5.6 8.7 9.3 6.7 3.6 10.3 8.7 7.1 13.0 7.6 6.2 6.2 4.1 6.9 7.8 0.0 0.0 0.1 0.6 0.0 0.0 1.0 0.5 0.3 0.0 0.2 0.0 0.0 0.7 2.1 0.0 0.1 2.7 0.5 0.3 0.4 0.4 0.6 0.4 0.4 0.4 0.3 0.3 0.2 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 80.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-reg: 16.1" "Group enriched" "Detected in all" 5 "NK-cells: 5.8;T-cells: 16.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: " "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavourable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavourable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavourable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 2.4 1.0 1.6 6.5 1.7 12.8 1.5 1.5 2.5 1.0 4.5 0.2 0.2 3.8 0.9 1.1 4.4 0.7 0.9 3.0 1.4 1.9 1.0 1.1 1.1 8.8 1.7 1.9 0.9 0.7 0.0 1.0 2.3 2.8 0.9 5.8 0.9 1.7 0.1 3.9 1.8 4.0 2.2 1.0 2.3 1.8 80.3 0.3 18.3 1.1 6.4 9.5 2.1 1.8 2.0 1.6 1.1 1.4 5.8 16.1 2.9 55.8 21.5 16.5 16.4 2.7 3.3 9.5 13.4 19.7 28.5 31.6 16.1 27.9 27.5 9.8 20.8 41.2 25.0 16.2 53.3 32.9 12.1 14.0 15.4 26.7 2.0 17.5 10.0 1.2 1.0 17.8 31.0 18.1 7.0 35.3 34.2 39.8 24.0 14.2 5.8 46.6 14.9 14.5 5.9 15.1 12.3 6.7 8.6 24.4 14.5 10.7 30.0 14.9 6.6 12.7 43.4 19.9 31.6 8.5 9.8 18.9 21.2 25.2 23.1 0.0 1.3 1.1 1.2 1.4 0.6 2.0 5.2 4.3 1.6 0.9 2.7 2.2 0.9 5.8 0.9 1.2 16.1 2.9 1.6 1.7 1.5 2.5 1.4 1.9 1.7 1.9 2.8 0.3 CELA1 ELA1 ENSG00000139610 "Chymotrypsin like elastase family member 1" Q9UNI1 12 51328443-51346679 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 6.3;blood: 12.6;pancreas: 11.8" "Cell line enriched" "Detected in some" 4 "BEWO: 10.7" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Cell type enhanced" "Detected in many" "basophil: 9.0;naive CD4 T-cell: 12.6" "Group enriched" "Detected in many" 7 "granulocytes: 9.0;T-cells: 12.6" "Low region specificity" "Detected in all" "Secreted - unknown location" "unprognostic (3.54e-2)" "unprognostic (1.64e-1)" "unprognostic (4.73e-2)" "unprognostic (2.73e-1)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (3.59e-2)" "unprognostic (3.83e-3)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" 0.0 6.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.0 11.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.9 9.0 1.6 0.2 12.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 9.0 1.6 0.1 1.1 0.8 0.4 0.3 2.7 0.8 0.9 0.0 12.6 5.9 0.2 0.2 0.9 0.0 0.3 1.3 CELA2A ELA2A ENSG00000142615 "Chymotrypsin like elastase family member 2A" P08217 1 15456728-15472091 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1559 "pancreas: 2376.3" "Cell line enhanced" "Detected in some" "HDLM-2: 1.1;HEL: 1.2;HL-60: 1.0;HMC-1: 4.9;K-562: 1.1;U-2 OS: 1.6" "Cancer enriched" "Detected in single" 3819 "pancreatic cancer: 463.9" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 15 "neutrophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Secreted to digestive system" "unprognostic (9.78e-2)" "unprognostic (3.33e-2)" "unprognostic (5.60e-2)" "unprognostic (5.27e-2)" "unprognostic (3.63e-3)" "unprognostic (2.35e-1)" "unprognostic (4.14e-1)" "unprognostic (1.96e-2)" "unprognostic (1.38e-1)" "unprognostic (2.48e-1)" "unprognostic (3.94e-9)" "unprognostic (4.10e-2)" "unprognostic (3.42e-1)" "unprognostic (3.55e-2)" 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.8 2376.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.7 1.2 0.0 0.0 0.0 1.0 4.9 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CELA2B "ELA2B, RP11-265F14.2" ENSG00000215704 "Chymotrypsin like elastase family member 2B" P08218 1 15465909-15491400 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 188 "pancreas: 697.9" "Cell line enriched" "Detected in some" 5 "U-138 MG: 9.1" "Cancer enriched" "Detected in single" 574 "pancreatic cancer: 69.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basophil: 3.7;neutrophil: 1.2" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.7" "Secreted to digestive system" "unprognostic (4.36e-3)" "unprognostic (5.45e-2)" "unprognostic (6.66e-2)" "unprognostic (5.31e-3)" "unprognostic (4.47e-3)" "unprognostic (1.37e-3)" "unprognostic (4.66e-2)" "unprognostic (6.32e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-1)" "unprognostic (2.94e-1)" "unprognostic (3.85e-2)" "unprognostic (1.22e-6)" "unprognostic (2.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.88e-1)" "unprognostic (7.80e-2)" 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 697.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.7 0.2 0.0 0.5 0.0 0.1 1.5 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.7 0.9 1.8 0.7 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.0 0.0 9.1 0.0 0.0 0.0 0.9 0.1 0.3 0.4 0.0 0.0 3.7 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 CELA3A "ELA3, ELA3A" ENSG00000142789 "Chymotrypsin like elastase family member 3A" P09093 1 22001656-22012539 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2051 "pancreas: 2541.2" "Cell line enriched" "Detected in single" 24 "MOLT-4: 21.1" "Cancer enriched" "Detected in some" 2497 "pancreatic cancer: 1481.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" Cytosol "HPA028086: , HPA045650: " "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" "unprognostic (1.79e-1)" "unprognostic (6.32e-2)" "unprognostic (2.67e-1)" 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.2 2541.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CELA3B "CBPP, ELA3B" ENSG00000219073 "Chymotrypsin like elastase family member 3B" P08861 1 21977021-21998642 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 196 "pancreas: 1614.4" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in single" 1218 "pancreatic cancer: 408.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" Cytosol "HPA028086: , HPA045650: " "unprognostic (2.89e-1)" "unprognostic (4.01e-3)" "unprognostic (6.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (6.40e-2)" 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 1614.4 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 5.9 5.3 8.2 3.0 2.3 3.2 0.9 0.6 4.9 1.7 1.3 2.5 1.5 2.2 1.1 1.8 1.7 1.7 5.3 2.7 5.4 2.6 1.4 1.6 1.0 0.5 0.0 2.4 4.1 2.4 4.9 3.9 1.3 1.9 3.2 2.3 2.4 1.4 0.0 2.4 2.5 5.5 0.4 2.5 2.1 1.5 1.3 3.5 3.6 0.9 4.2 0.0 3.6 3.1 1.7 3.4 0.8 0.3 2.5 2.8 3.6 2.9 1.6 2.3 1.0 4.8 4.7 2.4 1.8 4.7 0.6 5.1 2.5 1.8 3.1 3.0 2.0 3.7 2.2 2.8 1.4 5.9 3.2 3.0 8.2 2.3 1.7 5.3 2.9 0.9 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CEMIP "HYBID, IR2155535, KIAA1199, TMEM2L" ENSG00000103888 "Cell migration inducing hyaluronan binding protein" Q8WUJ3 15 80779343-80951776 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "endometrium 1: 33.9;lymphoid tissue: 116.9" "Group enriched" "Detected in some" 5 "BJ: 43.3;BJ hTERT+: 68.5;fHDF/TERT166: 54.4;HSkMC: 37.4;U-138 MG: 19.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted in other tissues" 560000 "unprognostic (1.14e-3)" "unprognostic (6.80e-2)" "unprognostic (5.95e-2)" "unprognostic (3.15e-3)" "unprognostic (3.49e-3)" "unprognostic (6.80e-2)" "unprognostic (5.47e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (1.53e-1)" "unprognostic (7.24e-2)" "unprognostic (1.36e-1)" "unprognostic (5.27e-10)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (1.34e-1)" "prognostic unfavourable (2.65e-4)" 6.7 2.1 1.7 11.6 5.0 1.7 1.0 6.8 8.9 2.4 6.9 6.4 2.6 1.2 33.9 7.8 7.1 7.0 2.8 6.4 2.2 2.8 1.1 1.0 16.6 116.9 14.1 9.4 5.3 1.4 0.7 9.1 2.9 15.6 2.5 2.4 15.4 5.9 3.2 4.3 6.2 1.6 0.9 13.6 2.0 1.3 3.3 1.1 0.0 4.4 0.7 5.0 6.5 3.1 0.9 1.5 0.6 0.5 0.2 1.3 0.2 0.1 1.6 0.3 0.2 0.1 0.6 0.2 43.3 68.5 1.1 0.9 0.5 0.2 0.2 0.1 54.4 1.0 0.0 0.1 0.2 0.1 0.4 0.1 0.2 3.5 0.4 0.1 0.2 37.4 0.0 8.5 0.0 0.0 0.2 0.1 1.0 0.9 0.1 0.1 0.2 1.9 0.2 0.0 0.1 0.0 0.7 2.7 0.1 0.7 0.1 3.6 0.2 0.0 0.2 19.8 0.2 1.4 0.7 0.1 0.1 0.2 2.1 0.3 1.3 0.0 0.3 0.0 0.4 0.4 0.1 0.6 0.0 0.2 0.0 0.9 0.0 0.7 0.6 0.2 0.5 1.5 1.3 0.2 1.7 5.0 6.8 8.9 2.2 2.8 14.1 9.4 15.6 1.1 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 355.0" "Group enriched" "Detected in some" 5 "Hep G2: 93.9;THP-1: 101.2" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 18 "classical monocyte: 32.6;myeloid DC: 32.9" "Group enriched" "Detected in many" 20 "dendritic cells: 32.9;monocytes: 32.6" "Not detected" "Not detected" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" 40000000 "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavourable (9.92e-4)" 27.1 1.7 0.3 0.5 0.4 2.1 24.7 0.4 0.6 3.1 8.9 0.5 1.5 2.4 7.3 2.1 4.5 6.7 57.7 8.1 0.3 0.0 0.7 355.0 19.8 2.3 0.3 0.6 3.9 1.3 0.0 0.8 1.1 0.6 11.2 1.0 3.8 3.9 4.0 1.6 1.4 3.5 10.2 0.7 4.4 7.0 1.0 0.3 0.4 1.7 2.3 1.5 8.2 16.1 0.2 32.9 0.2 32.6 0.1 1.6 12.1 0.0 0.6 0.0 0.0 14.1 0.0 0.4 0.0 0.0 0.0 0.0 6.5 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 93.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 101.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 20.3 0.0 0.0 32.6 0.1 1.3 1.8 0.5 0.2 0.2 1.6 32.9 0.2 0.2 0.4 0.2 0.1 0.4 1.7 0.1 12.1 0.3 0.4 0.4 0.6 0.3 0.0 0.3 0.6 0.6 0.3 CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "esophagus: 46.7;intestine: 146.9;liver: 78.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA018897 Enhanced Approved "Golgi apparatus,Cytosol" 7500000 "Golgi apparatus, Cytosol" "HPA018897: AB_1846558" "unprognostic (8.15e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-3)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (6.93e-2)" "unprognostic (7.99e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-2)" "prognostic favourable (1.50e-5)" "unprognostic (8.01e-2)" "unprognostic (1.53e-1)" "unprognostic (4.14e-2)" "unprognostic (1.38e-1)" 5.8 15.3 8.5 8.8 11.7 2.4 5.1 13.0 15.9 9.5 42.3 12.1 11.2 146.9 7.0 11.9 46.7 6.1 14.5 15.2 7.4 6.6 22.5 78.6 6.7 4.6 8.2 10.7 8.4 12.0 10.0 6.8 7.3 10.3 9.7 42.6 13.0 12.7 7.9 11.6 8.9 117.3 10.4 5.6 7.8 10.9 8.5 8.2 9.0 11.7 14.1 12.1 7.6 11.6 6.9 8.9 5.0 10.6 7.9 10.7 5.2 6.8 9.0 9.5 12.7 9.4 8.8 7.2 7.8 12.6 9.2 11.7 9.7 11.4 8.0 7.8 10.2 17.8 6.9 19.7 7.2 7.1 9.6 7.9 5.1 18.2 13.3 10.3 13.8 12.7 37.3 13.0 21.9 6.8 11.0 5.9 15.5 4.3 9.1 8.6 5.1 9.1 10.8 9.6 9.4 26.1 12.0 6.2 8.1 25.5 6.4 6.6 11.1 12.8 8.4 12.1 6.5 7.5 5.9 11.9 14.2 9.5 18.7 8.1 9.1 4.7 10.4 4.7 10.1 7.8 9.2 6.1 7.7 10.7 8.9 6.9 9.5 8.6 5.0 7.9 10.6 7.7 6.8 5.2 8.5 11.7 13.0 15.9 7.4 6.6 8.2 10.7 10.3 8.2 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961237-66975148 "Enzymes, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8;liver: 26.7" "Cell line enhanced" "Detected in many" "AN3-CA: 8.9;Daudi: 9.8;U-937: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" 1200000 "Nuclear membrane, Endoplasmic reticulum" "HPA041008: , HPA041307: " "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favourable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.5 0.1 0.8 13.3 1.3 0.2 1.0 1.6 1.3 0.6 40.7 0.7 1.4 16.8 0.4 0.7 2.2 1.5 3.0 0.7 1.5 1.0 6.8 26.7 0.9 0.2 0.8 1.1 0.5 7.8 0.0 1.1 0.4 2.2 0.4 17.9 1.1 5.9 0.6 12.9 0.5 41.8 0.5 0.9 0.2 4.6 0.9 0.6 0.5 0.4 2.4 0.5 0.4 0.3 0.7 0.6 2.7 0.6 0.3 0.9 0.2 0.5 3.5 0.4 8.9 0.3 0.2 1.4 0.3 0.2 0.4 0.6 0.5 4.4 9.8 3.0 0.0 0.7 1.4 0.7 0.2 1.6 6.5 4.9 1.4 2.9 0.1 1.1 0.7 0.4 1.1 1.0 0.2 0.0 3.1 2.1 0.4 1.4 1.6 1.7 1.5 0.6 1.5 0.8 1.5 0.1 0.5 0.5 1.0 0.3 6.7 0.2 5.9 7.5 0.4 0.5 2.8 0.8 0.2 1.1 4.0 1.4 0.3 8.3 0.3 0.6 0.6 2.7 0.3 0.3 0.5 0.5 0.6 0.4 0.6 0.7 0.9 0.6 2.0 0.3 0.4 0.3 0.9 0.2 0.8 1.3 1.6 1.3 1.5 1.0 0.8 1.1 2.2 0.6 CES5A "CAUXIN, CES4C1, CES5, CES7, FLJ31547" ENSG00000159398 "Carboxylesterase 5A" Q6NT32 16 55846154-55956031 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 43.4" "Cell line enriched" "Detected in single" 44 "U-266/70: 13.0" "Cancer enhanced" "Detected in single" "liver cancer: 0.6" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "unprognostic (2.07e-1)" "unprognostic (2.55e-1)" "unprognostic (6.34e-2)" "unprognostic (4.82e-2)" "unprognostic (3.78e-1)" "unprognostic (2.33e-1)" "unprognostic (3.12e-2)" "unprognostic (1.72e-7)" "unprognostic (1.55e-2)" "unprognostic (2.27e-1)" 0.1 0.1 0.7 0.1 0.6 0.0 0.1 0.1 0.8 0.1 0.1 0.1 3.6 0.0 0.1 43.4 0.1 0.0 1.4 0.1 0.8 0.5 0.1 6.6 0.1 0.1 1.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 1.2 0.3 0.1 1.2 0.1 0.1 1.8 0.1 0.0 1.7 0.1 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.1 0.8 0.8 0.5 1.4 0.1 0.1 0.1 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "liver: 461.5" "Cell line enhanced" "Detected in some" "ASC diff: 6.0;ASC TERT1: 5.8;CAPAN-2: 6.9;fHDF/TERT166: 11.3;HSkMC: 18.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" 878700000 180000000000 "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: , HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favourable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavourable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 9.3 1.0 0.3 4.1 0.4 0.3 2.4 0.2 0.4 1.3 9.0 0.4 0.9 3.2 0.5 3.7 2.2 4.0 8.9 3.3 0.2 0.0 16.1 461.5 2.5 2.1 0.7 0.1 2.8 5.8 0.4 1.0 4.0 1.0 4.0 1.6 2.6 3.1 0.3 0.5 0.5 4.7 2.6 0.6 0.8 4.1 1.4 0.3 0.3 1.8 0.5 1.7 1.6 0.4 0.1 1.6 0.0 0.8 0.0 0.2 0.0 0.0 1.8 0.1 0.1 6.0 5.8 0.0 0.0 0.3 1.5 0.6 0.0 6.9 0.1 5.1 11.3 0.0 0.0 1.9 1.4 0.4 0.3 0.4 0.3 0.5 0.0 0.7 0.1 18.7 0.1 0.9 0.6 0.2 0.2 0.7 0.1 0.1 0.1 0.4 0.3 0.1 0.2 0.4 0.2 1.6 0.0 0.0 0.0 0.5 1.2 0.2 0.0 0.2 0.0 0.2 0.5 0.3 0.3 0.5 1.9 0.5 3.1 0.5 0.5 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.3 0.4 0.2 0.3 0.2 0.0 0.7 0.1 1.0 0.3 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859643-863630 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "ASC diff: 39.8;THP-1: 56.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "basophil: 125.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 125.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" 731723333 8000000000 "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favourable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavourable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 161.3 4.6 0.0 16.4 0.0 5.6 96.7 0.0 1.7 44.2 35.2 0.2 42.2 10.9 8.9 89.8 54.1 15.6 59.0 102.0 0.0 0.0 1.9 2.3 34.0 6.2 0.0 0.0 13.7 6.0 1.7 0.1 20.2 0.1 102.0 4.3 3.4 22.7 15.1 40.5 35.8 16.5 97.3 0.1 3.7 19.7 33.6 0.0 0.8 52.6 55.6 9.0 83.7 130.3 0.6 5.6 125.0 25.8 0.1 1.0 10.4 0.7 1.9 0.0 0.3 39.8 6.2 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.5 0.2 0.0 0.0 1.1 2.8 0.0 1.7 0.6 0.6 0.3 1.0 6.3 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.9 0.0 8.9 0.1 2.8 0.2 0.0 0.9 0.0 0.1 0.3 0.3 0.8 0.2 0.0 1.1 56.5 0.0 0.0 0.9 0.4 0.1 1.7 0.7 0.0 0.0 3.3 0.0 125.0 18.2 58.8 0.7 20.1 1.0 0.6 0.5 0.9 5.6 0.2 0.7 0.8 43.2 0.1 25.8 0.5 0.3 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109802179 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "kidney: 90.7;liver: 198.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 28.9;Hep G2: 45.8;HSkMC: 19.0;RPTEC TERT1: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" 11000000000 "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavourable (6.06e-4)" 9.5 13.2 1.5 2.3 1.4 0.0 3.9 0.9 2.5 5.0 4.1 1.1 2.9 4.9 5.0 12.0 4.4 9.7 9.3 6.2 1.6 0.8 90.7 198.4 7.2 3.1 1.8 0.7 10.6 7.6 0.5 3.8 3.2 2.6 3.9 0.7 6.8 3.6 3.6 1.4 0.5 4.6 3.0 3.0 7.8 1.7 3.6 1.6 0.5 5.3 2.3 1.4 3.8 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.0 28.9 0.0 9.2 0.0 0.0 0.0 0.0 0.0 9.7 0.3 0.0 0.1 45.8 2.0 0.0 0.0 19.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 51.2 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.4 0.9 2.5 1.6 0.8 1.8 0.7 2.6 1.6 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "Cystic fibrosis transmembrane conductance regulator" P13569 7 117465784-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 103.0" "Group enriched" "Detected in some" 22 "CACO-2: 12.5;MOLT-4: 47.0;U-266/70: 25.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Region enriched" "Detected in many" 5 "olfactory region: 6.3" "CAB001951, HPA021939" Enhanced "CAB001951: , HPA021939: AB_1846578" "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavourable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.2 0.4 10.5 0.4 0.0 0.3 0.3 0.3 2.5 19.8 0.1 0.8 10.5 0.6 2.1 0.4 0.4 15.8 0.3 0.4 0.3 1.1 1.4 5.7 0.1 0.5 0.1 0.3 103.0 0.0 0.3 0.1 0.1 1.5 12.5 0.1 22.4 0.1 0.3 1.1 24.2 0.3 0.7 0.3 0.6 0.9 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.3 0.4 0.3 0.5 0.1 0.1 0.1 CHD1 ENSG00000153922 "Chromodomain helicase DNA binding protein 1" O14646 5 98853985-98928957 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease mutation, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022236 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoplasm, Nucleoli fibrillar center" "HPA022236: " "unprognostic (2.63e-1)" "unprognostic (2.31e-1)" "unprognostic (1.09e-2)" "unprognostic (4.11e-2)" "unprognostic (7.79e-2)" "unprognostic (7.15e-2)" "unprognostic (6.50e-2)" "unprognostic (1.00e-2)" "unprognostic (1.79e-1)" "unprognostic (2.88e-1)" "unprognostic (4.94e-2)" "unprognostic (3.15e-1)" "prognostic unfavourable (7.25e-6)" "unprognostic (2.69e-1)" "unprognostic (3.33e-1)" "unprognostic (1.52e-1)" "unprognostic (1.17e-1)" 13.0 7.4 5.5 15.8 7.5 41.7 10.2 14.9 5.5 9.4 9.3 4.7 7.9 6.6 11.3 7.5 7.6 10.8 10.6 6.8 4.9 3.1 7.3 10.1 12.1 8.8 8.8 3.2 18.1 8.3 9.3 12.0 11.1 6.4 7.7 7.4 5.6 8.1 11.5 13.2 8.2 12.3 8.3 7.2 17.2 8.6 12.0 7.4 70.1 8.1 5.5 9.3 10.4 11.3 10.1 7.1 16.7 8.2 8.1 8.4 2.2 11.4 10.5 24.8 16.8 8.4 8.7 21.7 11.9 7.8 9.7 12.6 13.1 8.9 9.7 11.6 6.9 9.6 19.4 13.1 20.3 15.2 14.6 17.2 12.6 9.9 9.3 16.5 13.4 7.5 5.4 16.8 17.0 11.7 20.7 15.0 9.7 9.2 32.8 7.2 16.7 12.8 27.9 17.4 14.6 8.5 11.0 11.6 9.9 15.3 8.0 19.3 7.7 11.4 13.1 20.8 11.2 13.0 21.0 10.5 11.0 20.7 11.4 16.6 12.5 11.4 8.2 10.7 6.5 7.5 8.2 10.1 6.1 6.1 7.1 9.4 8.4 6.6 16.7 8.1 7.1 5.2 6.3 2.2 5.5 7.5 14.9 5.5 4.9 3.1 8.8 3.2 6.4 7.4 CHD1L ALC1 ENSG00000131778 "Chromodomain helicase DNA binding protein 1 like" Q86WJ1 1 147242641-147295766 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027789, HPA028670" Enhanced Supported Nucleoplasm Nucleoplasm "HPA027789: AB_10601099, HPA028670: AB_10601257" "unprognostic (1.07e-1)" "unprognostic (3.93e-2)" "unprognostic (1.97e-1)" "unprognostic (3.49e-1)" "unprognostic (1.78e-1)" "unprognostic (2.58e-2)" "prognostic unfavourable (3.07e-4)" "unprognostic (1.86e-2)" "unprognostic (7.83e-2)" "unprognostic (1.39e-2)" "unprognostic (4.97e-2)" "unprognostic (8.21e-2)" "prognostic unfavourable (1.31e-9)" "unprognostic (5.51e-2)" "unprognostic (3.52e-1)" "unprognostic (2.74e-2)" "unprognostic (1.16e-1)" 11.2 12.2 16.1 14.1 16.5 26.9 18.2 23.0 20.0 9.8 16.1 29.5 6.4 18.4 16.0 12.2 10.4 13.4 12.5 9.2 17.3 13.6 11.8 26.1 13.7 16.1 27.3 12.6 9.5 18.5 12.6 17.9 11.8 18.2 13.2 20.0 11.6 9.5 11.9 12.0 15.9 20.9 18.4 24.7 21.3 12.9 27.8 22.2 18.5 8.9 9.4 16.9 8.5 11.9 15.3 19.0 7.6 8.3 8.2 9.1 9.0 19.2 16.7 19.2 12.2 13.5 13.2 15.9 17.3 14.7 16.3 15.4 16.1 13.4 25.1 8.1 17.3 18.4 16.2 18.9 14.4 24.9 22.7 24.1 13.4 41.1 14.3 31.0 15.5 12.2 9.3 16.0 18.4 17.8 27.5 11.7 19.7 21.4 23.5 16.7 25.2 22.1 26.4 17.8 19.8 15.3 13.8 11.6 19.6 15.7 19.7 15.1 10.7 45.2 16.1 11.0 16.7 9.9 27.0 10.1 14.0 20.8 22.4 13.7 16.6 7.6 8.1 3.7 9.0 6.8 9.1 12.5 7.9 7.8 19.0 15.3 8.0 8.9 0.8 8.2 8.3 15.8 5.5 9.0 16.1 16.5 23.0 20.0 17.3 13.6 27.3 12.6 18.2 22.2 CHD2 "DKFZp547I1315, DKFZp686E01200, DKFZp781D1727, FLJ38614" ENSG00000173575 "Chromodomain helicase DNA binding protein 2" O14647 15 92900189-93028005 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060744, HPA060960" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA060744: , HPA060960: " "unprognostic (1.65e-2)" "unprognostic (2.43e-1)" "unprognostic (2.14e-2)" "unprognostic (5.98e-2)" "unprognostic (2.12e-2)" "unprognostic (3.10e-2)" "unprognostic (2.67e-2)" "unprognostic (7.85e-2)" "unprognostic (7.51e-3)" "unprognostic (1.14e-1)" "unprognostic (2.84e-1)" "unprognostic (1.79e-2)" "unprognostic (4.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-1)" "unprognostic (1.70e-2)" 23.7 16.6 18.7 23.6 21.1 66.7 21.8 35.1 22.8 24.1 19.9 19.7 17.6 15.7 26.1 31.9 20.3 18.4 16.8 15.3 18.5 15.7 17.7 17.6 30.4 25.2 22.1 13.9 26.3 20.9 27.5 41.9 33.1 19.1 22.4 16.1 22.1 21.2 19.9 24.3 25.2 24.3 20.3 30.8 26.9 20.8 20.4 22.4 39.5 28.8 11.3 37.4 34.7 19.0 25.5 17.2 34.5 6.3 8.0 17.5 4.6 10.7 5.8 15.9 7.0 9.9 24.5 12.2 10.1 10.3 6.8 8.5 7.4 14.1 2.6 8.5 8.7 16.0 9.2 9.9 9.6 0.0 5.4 12.7 11.7 6.4 13.4 13.4 10.0 15.4 12.2 8.1 16.5 11.5 13.2 30.3 10.3 6.6 6.9 7.0 10.1 6.6 10.0 14.5 14.5 7.1 14.5 8.8 9.5 17.5 6.4 13.1 7.2 11.4 18.4 5.6 7.4 4.8 6.4 28.9 11.6 11.0 8.6 8.1 4.8 14.9 6.3 15.0 12.9 3.3 11.8 25.5 12.6 10.1 3.3 23.4 17.5 12.5 34.5 8.0 5.8 17.2 12.3 4.6 18.7 21.1 35.1 22.8 18.5 15.7 22.1 13.9 19.1 22.4 CHD3 "Mi-2a, Mi2-ALPHA, ZFH" ENSG00000170004 "Chromodomain helicase DNA binding protein 3" Q12873 17 7884806-7912760 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043368, HPA076524" Supported Approved "Nucleoplasm,Nucleoli,Centriolar satellite" "Nucleoplasm, Nucleoli, Centriolar satellite" "HPA043368: , HPA076524: " "unprognostic (1.77e-2)" "unprognostic (8.01e-2)" "prognostic unfavourable (2.43e-4)" "prognostic favourable (7.68e-5)" "unprognostic (1.53e-1)" "unprognostic (8.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.11e-1)" "unprognostic (2.83e-2)" "unprognostic (5.25e-3)" "prognostic favourable (8.36e-4)" "unprognostic (9.11e-2)" "unprognostic (8.31e-2)" "unprognostic (3.98e-2)" "unprognostic (1.50e-1)" "unprognostic (8.90e-3)" "unprognostic (2.20e-3)" 10.4 12.9 31.7 24.3 26.0 18.7 12.5 12.1 28.3 41.1 21.1 4.1 22.5 8.2 46.3 16.1 15.1 25.0 20.0 8.7 30.4 14.2 15.2 2.3 13.1 19.0 8.4 28.4 27.3 15.1 28.5 21.0 8.0 10.7 32.9 11.1 20.7 19.4 23.0 3.3 16.2 14.0 23.3 6.9 14.6 15.8 11.3 5.1 40.6 19.7 7.5 17.7 20.6 28.9 1.6 4.0 4.1 3.5 2.7 7.8 3.6 12.1 30.4 17.8 23.6 21.7 18.2 9.5 14.2 19.1 12.1 12.9 5.9 10.3 34.3 10.8 20.9 16.5 33.4 15.0 15.2 17.4 19.4 16.6 39.4 0.7 11.6 4.7 32.7 24.0 8.0 16.2 10.9 22.3 11.1 0.5 11.2 12.0 13.1 5.5 2.8 11.2 38.4 21.7 5.2 12.0 29.7 12.1 16.4 35.3 13.8 6.9 15.8 7.8 27.9 26.2 20.6 6.3 20.4 2.5 0.4 19.4 13.3 13.5 22.3 0.6 2.7 4.1 7.0 1.7 5.5 1.5 6.7 6.6 2.1 1.6 7.8 5.1 2.1 2.7 3.5 4.0 3.6 3.6 31.7 26.0 12.1 28.3 30.4 14.2 8.4 28.4 10.7 5.1 CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012008 Supported Enhanced Nucleoplasm Nucleoplasm "HPA012008: AB_1846633" "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.71e-2)" "unprognostic (6.40e-3)" "unprognostic (8.99e-2)" "unprognostic (3.36e-3)" "prognostic unfavourable (6.03e-6)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (9.84e-2)" "unprognostic (1.66e-1)" 23.5 34.9 21.9 50.0 33.5 27.2 25.9 29.4 25.1 28.1 29.5 29.3 38.5 18.6 37.2 35.4 29.1 28.0 40.3 52.8 23.5 19.2 29.5 25.0 25.5 30.9 33.6 19.4 34.6 27.4 58.4 25.3 29.5 27.2 21.5 26.0 26.5 24.8 46.2 33.7 31.1 24.4 36.6 30.3 29.4 27.2 29.7 28.9 75.7 38.4 33.7 38.4 34.7 24.3 12.6 16.8 12.8 9.1 13.5 16.7 5.8 20.5 18.7 46.5 17.4 19.1 21.5 27.3 22.8 22.2 25.2 23.2 31.2 16.0 44.2 9.1 25.7 18.4 43.6 25.1 34.0 33.0 22.4 61.7 29.1 19.5 16.6 48.4 29.6 20.7 12.5 24.3 17.1 29.3 48.5 22.1 23.9 25.7 45.9 15.8 44.5 17.7 39.4 28.6 24.1 15.9 24.3 22.0 28.3 29.3 32.6 22.6 14.9 27.6 27.2 25.7 54.8 18.8 26.6 35.8 21.3 56.4 17.0 29.6 18.8 9.0 7.7 9.2 12.2 9.1 12.0 10.5 10.3 11.1 7.9 12.6 13.0 12.3 12.8 13.5 8.1 16.8 16.7 5.8 21.9 33.5 29.4 25.1 23.5 19.2 33.6 19.4 27.2 28.9 CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101793-6180123 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.4;pituitary gland: 22.3;testis: 16.4" "Group enriched" "Detected in some" 4 "SCLC-21H: 16.6;U-2 OS: 7.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" 1.1 7.9 19.8 1.3 17.1 1.0 1.0 12.1 41.4 1.2 1.4 0.7 0.0 1.3 1.2 1.2 1.5 1.2 1.2 1.6 15.3 10.1 1.3 1.0 1.2 1.0 4.3 19.1 1.1 1.4 1.3 22.3 1.0 8.0 1.9 1.3 2.3 1.2 4.8 1.2 1.0 1.4 1.2 1.6 1.1 1.2 16.4 0.8 0.0 1.0 0.0 1.0 1.1 0.4 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.1 0.1 0.0 0.0 0.1 0.2 2.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.3 1.5 0.0 0.3 1.3 0.0 0.0 0.0 0.0 16.6 0.2 0.1 0.0 0.0 2.8 0.1 0.0 0.1 7.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 19.8 17.1 12.1 34.2 15.3 10.1 4.3 19.1 8.0 0.8 CHD6 "CHD5, dJ620E11.1, FLJ22369, KIAA1335, RIGB" ENSG00000124177 "Chromodomain helicase DNA binding protein 6" Q8TD26 20 41402101-41618494 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015543 Approved Nucleoplasm Nucleoplasm "HPA015543: " "unprognostic (5.13e-3)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.27e-1)" "unprognostic (6.66e-2)" "unprognostic (1.36e-1)" "unprognostic (4.72e-3)" "prognostic favourable (3.42e-4)" "unprognostic (1.17e-1)" "unprognostic (3.17e-1)" "unprognostic (4.75e-2)" "unprognostic (1.14e-1)" "unprognostic (2.12e-3)" "unprognostic (6.66e-2)" "unprognostic (3.41e-1)" "unprognostic (1.00e-1)" "unprognostic (1.14e-2)" 12.1 12.6 16.5 12.7 16.2 18.1 19.4 34.1 24.9 17.4 11.3 16.6 15.4 6.5 20.4 19.9 11.0 16.3 11.7 12.1 15.8 13.9 11.8 10.7 11.7 12.1 14.7 16.8 26.1 12.5 31.4 30.3 12.9 24.3 19.7 10.0 14.2 14.5 17.0 9.4 14.4 10.5 14.4 17.3 12.0 12.3 11.1 18.2 21.4 21.4 6.7 15.3 16.9 15.0 12.0 11.5 15.1 9.3 10.4 10.4 2.3 6.4 7.6 16.4 7.2 9.3 9.6 10.9 5.6 11.6 10.0 12.3 10.4 5.3 7.7 10.2 9.5 9.5 10.2 9.6 11.5 2.4 4.9 10.5 6.9 10.0 5.2 8.2 5.2 9.6 9.0 7.3 8.1 8.6 8.2 8.7 7.7 17.6 12.9 8.9 5.3 12.7 10.0 19.4 5.4 6.2 14.8 14.8 10.2 17.1 4.6 11.4 7.8 6.2 9.9 15.8 7.8 8.4 4.8 7.9 6.3 9.9 7.1 4.0 4.9 15.1 6.5 7.1 8.9 6.2 8.9 8.8 7.7 7.3 5.1 12.0 10.4 8.7 0.9 10.4 9.3 11.5 5.9 2.3 16.5 16.2 34.1 24.9 15.8 13.9 14.7 16.8 24.3 18.2 CHD7 "CRG, FLJ20357, FLJ20361, KIAA1416" ENSG00000171316 "Chromodomain helicase DNA binding protein 7" Q9P2D1 8 60678778-60868028 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.1" "Cell line enhanced" "Detected in many" "AF22: 25.8;SCLC-21H: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 15 "B-cells: 12.2;granulocytes: 12.6;T-cells: 5.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebellum: 110.3" HPA053075 Supported Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA053075: " "unprognostic (3.77e-2)" "unprognostic (3.28e-3)" "unprognostic (3.17e-2)" "prognostic unfavourable (5.34e-5)" "unprognostic (9.59e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-3)" "unprognostic (3.41e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (9.09e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-1)" "unprognostic (8.20e-2)" "unprognostic (2.17e-1)" 3.9 2.2 7.0 7.9 11.2 25.1 4.1 47.1 9.0 2.3 5.7 13.4 3.1 5.9 2.6 3.2 5.1 3.2 3.1 4.1 8.1 4.3 3.6 3.6 4.7 7.0 8.1 3.3 1.4 6.4 12.4 9.9 5.6 9.9 2.9 5.5 6.4 5.7 2.8 10.3 5.7 6.6 2.4 7.5 6.1 4.5 4.3 12.2 1.6 5.4 2.2 7.3 2.9 5.9 12.2 0.6 12.6 0.6 0.0 5.5 0.4 3.8 1.9 25.8 4.5 0.0 0.0 8.1 0.2 0.0 0.9 0.8 4.8 3.6 7.5 0.4 0.0 2.3 13.2 3.8 0.8 2.8 7.1 17.6 3.2 6.3 1.1 5.3 3.3 0.5 2.9 0.0 4.3 3.8 1.3 6.7 0.6 3.9 8.3 6.0 17.7 0.9 17.3 6.1 2.4 2.0 4.4 23.6 11.7 0.7 2.9 7.2 5.2 5.0 4.4 0.2 4.2 0.2 2.1 7.1 4.1 11.7 1.5 0.6 6.6 10.4 0.3 12.6 2.6 0.1 3.3 8.0 2.9 0.9 0.1 12.2 5.5 2.0 7.1 0.0 0.6 0.6 0.2 0.4 7.0 11.2 47.1 6.5 8.1 4.3 8.1 3.3 9.9 12.2 CHD8 "DUPLIN, HELSNF1, KIAA1564" ENSG00000100888 "Chromodomain helicase DNA binding protein 8" Q9HCK8 14 21385194-21456126 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052186, HPA076133" Enhanced "Nucleoplasm,Plasma membrane" Nucleoplasm "Plasma membrane" "HPA052186: , HPA076133: " "unprognostic (3.45e-1)" "unprognostic (9.71e-2)" "unprognostic (3.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "unprognostic (3.43e-1)" "prognostic unfavourable (4.94e-4)" "unprognostic (7.31e-2)" "unprognostic (9.22e-2)" "prognostic favourable (8.35e-4)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (2.54e-3)" "unprognostic (2.88e-1)" "unprognostic (9.24e-2)" "unprognostic (2.51e-1)" "unprognostic (8.07e-3)" 13.9 14.5 13.0 14.8 21.5 34.8 17.0 28.9 25.7 15.8 14.4 26.6 14.1 11.1 18.3 13.4 17.4 15.9 11.7 12.3 13.5 13.3 14.0 11.2 15.5 18.5 15.4 15.2 20.7 19.0 34.7 25.3 15.2 20.3 16.3 14.6 19.3 15.7 14.9 16.9 24.5 16.4 17.2 13.1 19.2 16.1 15.2 18.1 29.9 17.4 10.4 24.8 16.6 14.5 12.3 7.8 12.8 7.4 8.7 8.6 3.0 16.2 21.3 23.6 11.0 15.1 13.1 13.4 12.9 14.9 19.7 19.7 18.5 14.1 26.9 8.2 17.3 20.0 28.9 18.2 25.0 20.6 13.2 23.6 14.3 22.4 14.0 32.6 22.5 17.6 14.8 22.1 15.9 17.5 16.4 14.4 14.9 17.5 23.4 13.3 18.0 18.1 22.0 17.9 9.1 14.6 30.1 17.3 16.6 20.3 15.8 11.2 11.1 15.8 20.5 16.4 12.6 9.6 15.3 16.4 19.5 26.9 6.6 12.1 16.3 12.8 4.8 12.1 7.7 5.0 8.6 5.8 6.8 7.5 3.3 12.3 7.4 6.4 11.0 8.7 7.4 7.8 5.7 3.0 13.0 21.5 28.9 25.7 13.5 13.3 15.4 15.2 20.3 18.1 CHD9 "BC022889, FLJ12178, KIAA0308" ENSG00000177200 "Chromodomain helicase DNA binding protein 9" Q3L8U1 16 53055033-53329150 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 42.9" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042053, HPA049420" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA042053: , HPA049420: " "unprognostic (3.57e-2)" "unprognostic (3.73e-2)" "unprognostic (3.44e-3)" "unprognostic (2.42e-1)" "unprognostic (4.34e-2)" "unprognostic (4.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "unprognostic (7.75e-3)" "unprognostic (2.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.35e-2)" "prognostic favourable (1.84e-4)" "unprognostic (4.96e-2)" "unprognostic (1.74e-1)" "unprognostic (5.09e-2)" "unprognostic (2.87e-1)" 18.0 12.6 14.5 12.5 17.3 30.3 15.7 49.3 19.6 18.5 13.8 6.6 17.4 8.0 14.2 15.0 14.4 13.5 11.6 12.2 15.9 8.2 16.8 12.3 12.3 9.2 16.0 12.3 18.8 12.9 28.1 39.9 12.3 15.1 13.7 11.5 8.9 17.8 15.3 17.1 14.4 11.1 11.6 20.1 11.6 13.4 7.0 18.7 15.6 17.7 11.2 9.4 13.9 15.1 16.4 42.9 23.7 12.7 12.1 8.8 1.7 5.7 6.7 15.0 12.2 11.2 16.4 2.6 10.6 7.8 5.6 2.5 3.7 5.2 7.7 6.9 8.7 7.0 7.8 5.5 7.9 2.7 5.8 10.9 6.4 2.3 7.8 15.1 9.1 11.3 5.6 8.2 10.4 8.3 12.7 2.6 7.0 2.2 7.5 3.4 5.4 5.1 26.5 18.0 3.3 3.4 5.4 6.4 7.1 9.4 3.1 7.8 3.4 7.0 16.0 10.6 5.4 3.9 7.1 8.0 5.5 13.5 7.5 6.5 10.4 23.7 9.2 8.9 5.7 7.6 8.8 12.5 3.9 6.2 5.4 16.4 3.1 4.4 3.0 12.1 12.7 42.9 1.9 1.7 14.5 17.3 49.3 19.6 15.9 8.2 16.0 12.3 15.1 18.7 CHIA "AMCase, CHIT2, TSA1902" ENSG00000134216 "Chitinase, acidic" Q9BZP6 1 111290862-111320566 "Enzymes, Predicted intracellular proteins" "Apoptosis, Carbohydrate metabolism, Chitin degradation, Immunity, Inflammatory response, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 66.6" "Group enriched" "Detected in some" 4 "ASC diff: 5.9;HAP1: 3.1" "Cancer enhanced" "Detected in some" "lung cancer: 1.8;stomach cancer: 2.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.6" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" HPA059193 Approved "Intracellular and membrane" "HPA059193: " "unprognostic (8.00e-2)" "unprognostic (7.08e-2)" "unprognostic (2.02e-2)" "unprognostic (4.99e-2)" "unprognostic (7.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.7 0.5 0.8 0.3 0.1 0.1 0.1 0.0 0.5 1.0 13.2 0.2 0.1 0.1 0.1 0.1 0.6 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.1 0.1 66.6 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 1.6 0.7 0.0 0.1 0.6 0.6 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.7 0.2 0.2 0.0 1.6 0.6 0.0 0.0 0.6 0.0 0.7 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CHIT1 "CHI3, CHIT" ENSG00000133063 "Chitinase 1" Q13231 1 203212827-203273641 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 99.9;lymphoid tissue: 106.5" "Cell line enhanced" "Detected in some" "EFO-21: 2.7;LHCN-M2: 1.7;RH-30: 1.7;U-266/70: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 31.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 2.9;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 4 "granulocytes: 2.9;monocytes: 1.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA010575, HPA074844" Supported "Secreted to blood" 26410000 58000000 "HPA010575: AB_1078512, HPA074844: " "unprognostic (5.80e-3)" "prognostic favourable (2.02e-4)" "unprognostic (2.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.55e-2)" "unprognostic (6.36e-3)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-3)" "unprognostic (3.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" 99.9 0.2 0.2 0.4 0.3 26.7 5.5 0.1 0.3 5.9 0.6 0.5 0.1 0.0 2.5 0.2 0.3 0.1 0.2 0.6 0.2 0.1 0.1 0.4 22.1 106.5 0.4 0.1 1.4 1.1 0.0 0.2 0.4 0.5 0.6 0.5 0.3 0.3 0.1 0.1 0.3 0.7 0.2 9.4 4.3 0.1 0.1 0.1 2.3 0.9 0.2 0.5 0.1 0.3 0.5 0.2 2.9 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 2.7 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.7 0.2 0.0 0.0 0.1 0.2 0.0 1.7 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 2.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.9 0.0 1.1 0.2 0.0 1.3 0.2 0.3 0.1 0.3 0.2 0.1 0.4 0.1 0.5 0.1 CLPB "ANKCLB, FLJ13152, HSP78, SKD3" ENSG00000162129 "ClpB homolog, mitochondrial AAA ATPase chaperonin" Q9H078 11 72285495-72434680 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 87.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 18.3" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039005, HPA039006, HPA064571" Enhanced "HPA039005: AB_2676305, HPA039006: AB_10672767, HPA064571: " "unprognostic (9.36e-2)" "unprognostic (1.06e-2)" "unprognostic (2.51e-1)" "unprognostic (1.23e-1)" "unprognostic (2.99e-1)" "unprognostic (2.05e-2)" "unprognostic (8.22e-2)" "unprognostic (8.37e-2)" "unprognostic (2.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.01e-2)" "unprognostic (1.18e-1)" "prognostic favourable (8.36e-8)" "unprognostic (9.29e-2)" "unprognostic (1.25e-1)" "unprognostic (5.83e-2)" "unprognostic (3.28e-2)" 4.4 6.1 5.7 4.8 7.2 7.9 3.4 5.6 10.5 3.1 3.1 6.7 2.5 3.2 3.8 3.1 3.7 2.9 2.9 4.1 4.9 4.1 6.7 8.5 3.7 3.0 5.7 5.9 3.2 5.5 8.6 3.4 6.5 7.9 2.7 3.1 3.1 4.2 3.3 6.5 2.8 2.9 4.5 3.9 3.9 3.7 87.9 6.4 2.7 4.7 1.8 2.9 3.7 3.0 1.6 18.3 4.0 11.7 1.8 2.4 5.2 6.4 18.5 5.8 11.9 7.9 5.8 15.0 7.0 4.3 10.5 7.9 24.7 9.8 16.7 16.1 6.6 13.8 15.5 15.3 12.9 15.1 11.6 14.1 19.2 14.7 6.8 14.1 25.1 7.7 5.1 18.6 18.8 11.8 19.1 11.8 7.5 17.1 12.7 13.4 6.1 18.5 11.6 8.7 7.2 6.1 11.1 14.6 11.1 9.5 21.9 16.3 11.3 12.3 9.2 15.0 9.7 15.1 13.5 5.7 8.1 9.5 8.0 12.0 11.4 4.0 11.7 0.6 2.4 9.3 2.4 1.5 1.4 2.1 18.3 1.6 1.8 1.4 1.0 1.8 5.2 3.3 0.8 5.2 5.7 7.2 5.6 10.5 4.9 4.1 5.7 5.9 7.9 6.4 CLPP ENSG00000125656 "Caseinolytic mitochondrial matrix peptidase proteolytic subunit" Q16740 19 6361452-6368910 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010649 Supported Supported Mitochondria Mitochondria "HPA010649: AB_1078538" "unprognostic (2.28e-1)" "unprognostic (7.14e-2)" "unprognostic (2.82e-1)" "unprognostic (4.34e-2)" "unprognostic (2.17e-2)" "unprognostic (1.15e-2)" "unprognostic (6.17e-3)" "unprognostic (7.43e-2)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "prognostic favourable (6.50e-4)" "unprognostic (1.21e-1)" "unprognostic (5.65e-2)" "unprognostic (6.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.86e-3)" 22.1 27.3 18.4 22.5 18.8 20.1 19.9 16.6 20.9 16.1 23.2 17.9 22.2 25.4 16.9 15.1 26.6 15.3 19.2 28.9 17.4 16.7 28.5 64.7 15.5 35.5 19.0 15.2 23.7 32.7 11.6 18.5 18.4 13.6 19.1 14.1 18.6 26.3 23.4 73.1 17.8 26.0 14.8 16.7 21.2 21.3 21.1 11.4 54.8 27.0 25.1 25.3 20.7 23.2 29.7 37.5 14.9 20.0 27.6 46.3 32.9 31.6 21.1 15.4 28.1 9.7 13.5 16.0 18.8 13.8 26.8 24.0 16.9 11.6 31.9 29.3 15.0 19.8 15.2 23.7 10.1 33.1 47.9 23.5 18.6 25.0 26.3 21.2 31.1 17.1 17.4 18.6 20.8 26.0 23.2 43.2 17.5 37.0 36.3 22.2 22.2 49.4 25.6 18.6 48.3 19.9 17.7 25.5 24.4 11.9 29.1 27.6 15.0 30.4 18.1 17.7 16.4 41.6 35.4 55.6 46.4 30.7 24.3 29.9 28.1 5.5 20.0 10.5 28.0 17.7 33.2 28.3 39.9 34.5 24.1 29.7 35.2 34.1 14.9 27.6 12.1 37.5 46.3 32.9 18.4 18.8 16.6 20.9 17.4 16.7 19.0 15.2 13.6 11.4 CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 1.6;BEWO: 1.5;HL-60: 1.7;TIME: 1.5;U-937: 3.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "T-reg: 1.5" "Lineage enriched" "Detected in single" 4 "T-cells: 1.5" "Low region specificity" "Detected in single" "CAB000363, HPA052634" Enhanced "Secreted to blood" 3000000 "CAB000363: AB_2083616, HPA052634: " "unprognostic (1.37e-1)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (7.07e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.21e-1)" "unprognostic (8.91e-3)" "unprognostic (4.19e-3)" "unprognostic (1.29e-4)" "unprognostic (2.52e-3)" "unprognostic (7.78e-2)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" 12.3 0.2 0.2 2.9 0.2 0.0 15.9 0.2 0.2 7.3 6.2 0.2 1.2 0.1 2.9 6.0 8.3 1.0 10.0 10.3 0.2 0.2 2.0 0.8 1.1 1.6 0.2 0.2 0.6 0.9 0.5 0.5 0.7 0.3 6.0 6.9 3.0 5.9 1.3 1.2 13.0 5.3 6.2 0.2 0.5 2.4 2.7 0.2 1.0 0.4 7.9 3.9 4.1 2.0 0.3 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 1.7 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.9 1.1 1.1 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.8 0.0 0.8 1.5 0.0 0.3 0.3 0.3 0.9 1.0 0.3 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534440-74587212 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 60.3;liver: 41.4" "Cell line enriched" "Detected in single" 69 "U-266/84: 41.2" "Group enriched" "Detected in some" 10 "glioma: 4.4;liver cancer: 1.0;melanoma: 1.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA008933 Enhanced "Secreted in brain" 1900000000 "HPA008933: AB_1847033" "unprognostic (7.43e-3)" "unprognostic (6.00e-2)" "unprognostic (8.55e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (6.90e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" 1.1 1.2 14.9 1.2 28.2 1.3 1.1 4.5 60.3 1.1 1.1 54.9 0.0 5.7 1.1 2.1 1.1 1.1 1.3 1.1 28.9 15.1 1.9 41.4 1.1 1.2 44.1 12.9 1.1 1.2 1.1 0.1 1.1 50.0 1.2 1.1 0.5 1.1 1.3 2.2 1.1 1.9 1.1 51.1 1.1 1.2 1.4 28.8 0.0 1.3 0.0 1.1 1.1 0.0 0.7 0.7 1.9 0.5 1.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 41.2 0.0 0.0 0.0 0.0 1.3 0.5 0.4 0.4 0.2 0.2 0.3 0.3 0.2 0.1 0.7 0.4 0.4 1.9 1.0 0.2 0.7 0.2 0.2 14.9 28.2 4.5 22.5 28.9 15.1 44.1 12.9 50.0 28.8 CNDP2 "CN2, CPGL, FLJ10830, HsT2298, PEPA" ENSG00000133313 "Carnosine dipeptidase 2" Q96KP4 18 74495816-74523454 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 75.1;RPMI-8226: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026196, HPA036898, HPA036899" Enhanced Enhanced Nucleoplasm,Cytosol 2400000 "Nucleoplasm, Cytosol" "CAB026196: , HPA036898: AB_2675370, HPA036899: AB_2675371" "unprognostic (2.81e-2)" "unprognostic (9.96e-2)" "unprognostic (3.28e-1)" "unprognostic (1.19e-3)" "unprognostic (2.57e-2)" "unprognostic (5.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.49e-1)" "unprognostic (9.31e-2)" "unprognostic (1.56e-3)" "unprognostic (1.15e-1)" "prognostic favourable (3.50e-6)" "unprognostic (2.37e-3)" "unprognostic (4.65e-3)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" 19.0 11.5 31.0 19.1 36.0 6.1 16.9 10.4 33.0 39.4 37.6 45.2 27.0 51.3 12.5 35.3 20.4 38.9 25.9 11.6 31.1 26.4 89.0 66.4 22.1 23.0 36.1 24.1 11.4 27.6 15.7 13.7 28.8 27.2 34.7 22.2 14.1 16.9 32.7 7.5 11.8 71.1 10.4 39.4 39.2 27.2 6.5 32.5 10.9 43.9 11.6 21.4 28.4 12.0 29.6 49.0 12.5 44.4 31.4 23.9 30.3 10.0 13.6 9.9 9.3 12.1 7.2 41.6 10.6 10.0 14.5 14.5 7.9 10.8 12.7 13.5 11.5 15.3 15.0 20.1 10.4 19.0 5.9 12.6 6.9 12.5 17.6 24.7 19.7 10.8 15.5 12.5 22.7 12.7 13.3 75.1 9.6 11.3 13.1 11.8 14.9 8.1 14.3 11.4 96.6 57.1 42.2 10.7 5.6 8.3 59.0 14.1 24.7 10.2 13.2 15.6 13.3 3.4 7.1 14.1 57.6 17.0 10.5 18.1 13.0 7.8 30.0 12.5 21.8 44.4 23.8 28.9 17.6 20.3 49.0 29.6 19.1 20.7 4.4 31.4 43.1 43.0 23.9 30.3 31.0 36.0 10.4 33.0 31.1 26.4 36.1 24.1 27.2 32.5 CNOT6 "CCR4, Ccr4a, KIAA1194" ENSG00000113300 "CCR4-NOT transcription complex subunit 6" Q9ULM6 5 180494412-180578405 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Activator, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044568 Approved Approved Cytosol Cytosol "HPA044568: AB_10797257" "unprognostic (9.41e-3)" "unprognostic (1.40e-1)" "unprognostic (2.03e-3)" "unprognostic (2.55e-1)" "unprognostic (1.41e-1)" "unprognostic (2.59e-1)" "prognostic unfavourable (3.61e-7)" "unprognostic (1.31e-1)" "unprognostic (1.10e-2)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-1)" "unprognostic (4.03e-2)" "unprognostic (3.57e-2)" 10.2 10.1 19.2 15.4 20.2 14.4 13.3 43.9 18.7 12.0 16.4 11.7 9.7 16.2 13.1 12.4 19.6 13.3 12.7 13.0 15.9 11.1 14.1 8.6 13.0 14.3 12.3 14.0 14.8 10.3 13.4 12.7 17.6 12.9 13.9 16.2 14.3 13.4 10.9 8.3 14.4 20.6 13.4 12.3 17.0 13.7 17.6 14.9 25.1 12.6 10.0 18.4 16.9 24.5 2.2 2.5 3.4 5.8 2.1 4.5 1.7 10.8 13.1 27.0 21.5 4.5 5.2 27.9 8.0 5.4 10.6 12.7 16.0 16.0 11.5 12.2 5.2 11.5 22.5 26.6 12.5 33.7 11.3 12.5 17.7 10.2 6.7 14.6 9.2 4.3 12.9 7.8 16.7 12.9 13.3 11.1 9.8 22.4 18.5 8.8 7.9 6.3 17.1 13.6 8.2 11.7 21.6 19.8 16.7 13.5 18.1 11.5 22.6 14.8 14.0 11.4 13.1 8.2 14.1 7.3 13.0 12.2 10.8 20.1 9.3 1.5 2.6 3.4 3.8 4.1 4.0 2.0 3.3 2.3 2.4 2.2 4.5 4.4 2.2 2.1 5.8 2.5 2.3 1.7 19.2 20.2 43.9 18.7 15.9 11.1 12.3 14.0 12.9 14.9 CNOT6L "Ccr4b, DKFZp434K098" ENSG00000138767 "CCR4-NOT transcription complex subunit 6 like" Q96LI5 4 77713387-77819615 "Enzymes, Predicted intracellular proteins" "mRNA processing, RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 51.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042688 Uncertain Supported Cytosol Cytosol "HPA042688: AB_10794384" "unprognostic (3.91e-1)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.10e-2)" "unprognostic (2.56e-1)" "unprognostic (3.72e-2)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (5.06e-2)" "unprognostic (6.86e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic favourable (1.69e-4)" "unprognostic (4.51e-2)" "unprognostic (7.95e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-3)" 13.6 7.8 8.6 21.5 8.2 15.3 11.0 11.1 9.2 7.8 7.3 7.0 4.6 7.5 11.4 6.3 10.2 7.1 8.3 7.5 6.0 5.7 7.7 10.8 12.7 19.2 7.6 7.3 8.8 10.8 14.6 10.0 12.3 6.7 8.4 8.9 10.3 9.9 7.4 9.1 12.2 11.5 8.4 6.9 23.4 7.9 7.3 5.6 51.3 9.1 6.2 21.1 10.7 10.3 7.5 6.1 20.2 9.3 7.4 10.0 4.4 8.6 5.6 7.1 4.7 8.4 7.3 7.0 6.9 9.1 6.2 8.4 2.2 9.7 15.0 8.8 9.6 5.6 9.1 9.6 8.3 15.0 5.1 14.0 7.8 6.3 5.3 13.9 12.3 4.7 12.4 6.9 12.8 19.6 11.7 20.1 7.1 5.9 25.7 7.0 3.2 1.8 6.3 20.0 10.7 7.1 9.8 8.7 4.2 11.9 10.9 4.8 3.5 7.2 21.3 6.0 6.6 11.3 3.8 25.8 11.0 18.7 6.5 6.1 4.4 20.2 4.7 10.2 10.0 7.0 10.0 5.3 7.5 7.8 4.5 7.5 7.3 8.5 6.7 7.4 9.3 6.1 6.0 4.4 8.6 8.2 11.1 9.2 6.0 5.7 7.6 7.3 6.7 5.6 CNOT7 CAF1 ENSG00000198791 "CCR4-NOT transcription complex subunit 7" Q9UIV1 8 17224964-17246878 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069543 Supported "Nuclear bodies" "Nuclear bodies" "HPA069543: " "unprognostic (1.55e-1)" "unprognostic (4.49e-2)" "prognostic favourable (4.99e-4)" "unprognostic (4.61e-2)" "unprognostic (8.45e-2)" "unprognostic (3.10e-2)" "unprognostic (1.44e-3)" "unprognostic (4.54e-2)" "unprognostic (6.83e-2)" "unprognostic (4.09e-3)" "unprognostic (2.51e-1)" "unprognostic (1.74e-1)" "unprognostic (3.49e-2)" "unprognostic (1.72e-1)" "unprognostic (4.51e-1)" "unprognostic (2.24e-1)" "unprognostic (2.52e-1)" 18.3 25.8 28.7 23.8 37.0 24.2 23.3 34.6 31.8 17.5 22.8 15.9 19.8 20.8 22.2 26.1 24.5 20.6 19.8 21.4 22.3 29.3 28.2 36.8 17.9 32.0 22.3 22.5 25.9 28.0 40.4 29.7 25.0 23.1 19.3 24.6 18.2 32.3 22.4 43.2 18.5 22.7 20.6 19.8 27.6 19.0 26.9 22.4 60.6 33.6 19.6 34.3 25.5 19.4 57.8 49.9 46.6 50.7 45.2 67.0 52.2 20.6 25.6 38.6 28.6 16.3 17.2 26.7 26.7 22.8 31.0 27.6 29.9 16.6 28.6 29.4 23.3 16.6 40.6 33.6 45.3 11.8 19.5 37.6 19.8 32.2 21.0 25.2 23.3 16.4 28.0 26.4 28.3 36.9 31.4 31.9 31.2 16.2 61.9 23.6 42.5 19.6 33.8 28.7 21.5 27.0 45.6 48.7 32.6 18.8 16.8 30.4 20.1 21.5 24.6 23.2 32.9 25.8 29.9 16.6 52.8 50.1 21.7 24.1 22.8 46.3 43.3 46.6 38.1 50.7 45.3 57.8 52.9 45.2 49.9 57.1 67.0 52.7 37.9 45.2 43.5 44.9 57.5 52.2 28.7 37.0 34.6 31.8 22.3 29.3 22.3 22.5 23.1 22.4 CNOT8 "CAF1, CALIF, hCAF1, POP2" ENSG00000155508 "CCR4-NOT transcription complex subunit 8" Q9UFF9 5 154857553-154876793 "Enzymes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051398 Approved "HPA051398: " "unprognostic (2.51e-1)" "unprognostic (4.26e-1)" "unprognostic (1.69e-2)" "unprognostic (1.48e-1)" "unprognostic (1.68e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (5.33e-4)" "unprognostic (1.19e-1)" "unprognostic (3.62e-2)" "unprognostic (2.35e-2)" "unprognostic (1.79e-2)" "unprognostic (2.80e-1)" "unprognostic (3.32e-3)" "unprognostic (2.19e-1)" "unprognostic (1.84e-1)" "unprognostic (3.66e-2)" "prognostic favourable (6.41e-4)" 40.5 28.0 23.6 20.9 23.8 60.1 30.3 20.3 29.2 26.0 23.5 21.3 19.5 19.0 21.1 22.5 18.2 18.2 17.5 17.2 23.2 16.1 17.1 16.6 33.5 30.5 33.0 18.3 20.0 16.2 20.1 17.8 23.9 24.4 17.4 27.5 16.5 24.1 17.5 14.3 28.0 23.7 23.2 25.9 30.7 19.1 24.4 26.2 41.5 36.0 11.3 29.5 24.6 22.8 20.5 33.4 65.4 31.9 20.9 31.5 36.6 12.0 13.9 24.2 26.6 23.2 21.2 18.4 18.6 20.7 20.5 31.9 17.8 27.0 21.2 23.5 15.9 13.3 16.7 23.1 23.4 10.5 17.3 17.7 21.6 15.7 14.7 40.7 33.0 14.4 20.3 18.3 15.9 25.2 15.6 16.0 21.4 14.4 35.9 42.6 13.1 8.2 30.2 20.5 22.0 16.2 16.7 19.0 28.4 24.9 20.1 23.1 18.8 33.5 19.5 21.8 13.7 11.9 12.2 15.5 19.9 32.6 15.3 32.5 13.5 55.0 31.9 65.4 19.3 22.6 21.4 20.5 24.0 23.1 33.4 20.4 31.5 22.7 32.2 20.9 17.7 18.0 26.0 36.6 23.6 23.8 20.3 29.2 23.2 16.1 33.0 18.3 24.4 26.2 CNP ENSG00000173786 "2',3'-cyclic nucleotide 3' phosphodiesterase" P09543 17 41966741-41977731 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 211.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 49.1" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002672, HPA023266, HPA023278, HPA023280, HPA023338" Enhanced Supported Enhanced Nucleoplasm,Cytosol 730000 Nucleoplasm Cytosol "CAB002672: , HPA023266: AB_1847058, HPA023278: AB_1847060, HPA023280: AB_1847061, HPA023338: AB_1847062" "unprognostic (2.17e-1)" "unprognostic (4.48e-2)" "unprognostic (3.85e-3)" "unprognostic (1.41e-1)" "unprognostic (3.09e-1)" "unprognostic (9.71e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.87e-1)" "unprognostic (2.99e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.10e-3)" 9.1 8.9 51.4 9.5 72.8 6.7 8.1 13.4 125.3 10.3 7.5 211.7 2.3 7.1 8.0 12.7 15.0 9.3 10.8 7.6 78.4 40.7 14.7 9.6 6.7 10.5 86.7 49.0 11.2 9.2 5.8 4.4 7.8 66.7 11.7 6.4 3.6 15.1 13.2 7.6 11.1 6.4 10.1 160.2 7.1 7.4 4.6 63.5 2.1 7.2 2.2 11.2 9.8 5.7 9.9 49.1 7.3 13.1 7.3 7.5 9.1 13.7 23.5 22.3 27.5 19.1 18.0 9.6 17.2 26.5 44.8 50.6 18.4 12.6 14.6 13.9 22.4 23.7 15.0 11.4 15.6 14.5 19.0 14.2 16.2 31.9 20.6 13.8 12.9 29.7 8.2 24.5 6.0 20.4 10.0 12.0 15.6 8.7 35.4 12.5 5.2 16.8 22.1 32.8 14.2 11.9 14.1 13.1 17.7 21.8 32.9 38.3 14.7 20.7 20.4 17.5 19.2 23.7 20.3 13.5 15.3 11.7 17.3 10.7 68.2 4.9 12.1 7.3 7.5 13.1 5.9 9.9 6.5 6.0 11.1 7.0 5.9 6.9 2.6 7.3 10.3 49.1 7.2 9.1 51.4 72.8 13.4 93.8 78.4 40.7 86.7 49.0 66.7 63.5 CPA1 CPA ENSG00000091704 "Carboxypeptidase A1" P15085 7 130380339-130388114 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3231 "pancreas: 3541.6" "Cell line enriched" "Detected in some" 5 "AN3-CA: 15.8" "Cancer enriched" "Detected in some" 639 "pancreatic cancer: 1377.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021836, CAB025197, HPA052215" Enhanced "Secreted to digestive system" 17000000 "CAB025197: , HPA021836: AB_1846005, HPA052215: " "unprognostic (8.41e-2)" "unprognostic (9.24e-4)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (3.97e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-6)" "unprognostic (4.99e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (4.37e-2)" 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.0 3541.6 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.0 0.3 0.0 1.9 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266827-130289798 "Enzymes, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 529 "pancreas: 1357.9" "Cell line enhanced" "Detected in some" "AN3-CA: 4.4;CACO-2: 7.3;RH-30: 6.1;SCLC-21H: 3.3" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" 1500000 "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.4 1357.9 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 0.1 2.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 4.4 0.0 0.1 0.0 0.0 0.0 0.7 0.0 7.3 0.0 0.0 1.0 0.0 0.0 1.4 0.0 0.1 1.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.4 0.0 6.1 0.1 0.1 0.6 3.3 0.0 0.2 0.0 2.0 0.0 0.2 0.0 0.0 1.1 0.8 0.6 0.0 0.7 0.2 0.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865256-148897196 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 111.7" "Cell line enriched" "Detected in some" 43 "HEL: 79.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1118 "basophil: 111.7" "Lineage enriched" "Detected in single" 1118 "granulocytes: 111.7" "Low region specificity" "Detected in single" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" 12.4 0.6 0.4 12.0 0.4 5.6 6.2 0.4 0.5 25.4 14.1 0.8 4.4 7.1 14.1 21.2 16.5 3.7 50.9 4.5 0.4 0.2 5.8 2.8 37.3 15.2 0.4 0.4 2.0 7.2 0.7 0.8 1.3 0.5 37.3 16.4 8.5 8.8 5.8 1.4 12.7 20.2 24.3 0.4 1.0 13.7 7.1 0.4 3.6 1.4 9.9 7.1 14.0 8.9 0.0 0.0 111.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 79.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 111.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.4 0.5 0.4 0.2 0.4 0.4 0.5 0.4 CPB1 ENSG00000153002 "Carboxypeptidase B1" P15086 3 148791102-148860187 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 590 "pancreas: 3628.4" "Cell line enhanced" "Detected in some" "ASC diff: 2.7;EFO-21: 2.9;HDLM-2: 3.0;U-2 OS: 5.1;U-251 MG: 1.5;U-266/84: 2.4" "Group enriched" "Detected in some" 312 "breast cancer: 293.8;pancreatic cancer: 641.4" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "CAB026158, HPA038069, HPA046340" Enhanced "Secreted to digestive system" 6600000 "CAB026158: , HPA038069: , HPA046340: " "unprognostic (6.90e-2)" "unprognostic (3.79e-2)" "unprognostic (3.34e-2)" "unprognostic (2.64e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (6.26e-4)" "unprognostic (1.90e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (7.59e-2)" "unprognostic (4.51e-2)" "unprognostic (5.50e-8)" "unprognostic (3.08e-1)" "unprognostic (1.60e-1)" "unprognostic (4.93e-2)" 0.2 1.7 0.1 0.1 0.2 0.0 0.7 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.2 3628.4 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.7 0.2 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 1.8 1.1 6.1 1.0 3.1 3.5 0.9 0.0 0.0 0.0 0.0 2.7 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 2.9 0.0 0.0 0.0 0.0 0.1 3.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 5.1 0.0 1.5 0.0 2.4 0.6 0.0 0.0 0.0 6.1 0.7 1.1 3.0 0.9 2.2 0.9 1.3 2.6 0.3 1.8 0.9 3.5 4.5 3.1 1.0 1.1 0.6 0.9 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 CPB2 "CPU, PCPB, TAFI" ENSG00000080618 "Carboxypeptidase B2" Q96IY4 13 46053195-46105033 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 82 "liver: 246.8" "Cell line enriched" "Detected in single" 76 "Hep G2: 61.1" "Cancer enriched" "Detected in some" 112 "liver cancer: 268.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA004146 Approved "Secreted to blood" 14000000000 "HPA004146: AB_1078397" "unprognostic (3.44e-2)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (1.89e-2)" "unprognostic (7.69e-2)" "unprognostic (1.17e-2)" "prognostic favourable (2.06e-4)" "unprognostic (1.89e-1)" "unprognostic (2.74e-1)" "unprognostic (2.48e-1)" "unprognostic (3.17e-2)" "unprognostic (4.83e-2)" "unprognostic (3.20e-3)" "unprognostic (1.34e-1)" "unprognostic (7.10e-2)" "unprognostic (3.34e-2)" "unprognostic (9.61e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 246.8 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.5 0.5 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 61.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.4 0.2 0.5 0.4 0.5 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 CPD GP180 ENSG00000108582 "Carboxypeptidase D" O75976 17 30378905-30469989 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HSkMC: 57.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 19.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052796, HPA055465" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear speckles" 930000 "Nucleoplasm, Nuclear speckles" "Nuclear membrane" "HPA052796: , HPA055465: " "unprognostic (1.05e-1)" "unprognostic (1.31e-1)" "unprognostic (3.05e-2)" "unprognostic (3.62e-2)" "unprognostic (6.13e-2)" "unprognostic (1.65e-1)" "unprognostic (7.97e-3)" "unprognostic (4.45e-2)" "unprognostic (2.07e-2)" "unprognostic (2.96e-1)" "unprognostic (1.62e-1)" "unprognostic (3.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.74e-2)" "unprognostic (7.25e-2)" "unprognostic (3.36e-1)" "unprognostic (1.08e-1)" 16.4 8.0 9.8 12.3 12.4 18.1 17.9 9.1 13.3 28.6 16.2 18.5 10.1 12.9 12.6 10.1 10.0 15.2 33.6 10.5 12.8 10.4 13.4 26.8 20.0 14.2 22.1 11.4 7.8 14.7 21.2 14.9 22.3 13.9 11.4 13.3 7.5 59.7 7.9 10.0 7.8 22.0 15.1 25.9 7.9 24.6 25.0 13.5 5.8 37.2 7.7 10.0 11.5 11.6 0.4 3.4 19.3 5.5 2.1 3.8 2.5 12.1 18.5 16.1 16.5 16.8 32.0 5.8 16.8 24.6 11.7 14.4 21.7 7.9 1.5 21.4 19.2 8.7 10.4 21.2 19.7 5.7 14.9 3.4 11.4 13.4 20.4 22.6 9.1 57.0 9.5 14.9 14.5 23.6 6.7 18.0 9.3 2.3 7.2 6.2 4.5 4.2 7.0 18.7 4.7 21.8 13.9 4.0 10.2 20.0 17.3 8.7 16.4 15.7 28.1 11.7 7.7 18.1 16.0 7.2 15.1 5.1 14.9 14.8 9.8 2.8 5.5 6.4 3.4 2.8 3.8 0.2 1.7 2.8 3.4 0.4 1.4 1.7 19.3 2.1 2.3 0.4 1.1 2.5 9.8 12.4 9.1 13.3 12.8 10.4 22.1 11.4 13.9 13.5 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498320 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 203.7" "Cell line enhanced" "Detected in many" "Hep G2: 49.9;SCLC-21H: 70.2;SiHa: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.5" "Lineage enriched" "Detected in single" 16 "T-cells: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" 470000 Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: " "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavourable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavourable (2.12e-4)" 27.7 33.8 123.1 4.4 135.5 0.9 21.5 82.9 203.7 10.7 9.6 31.6 5.3 5.0 13.3 94.3 16.4 15.7 14.0 19.6 116.9 56.3 12.0 6.3 11.0 7.6 56.9 70.7 23.4 35.5 33.9 40.0 2.2 53.0 66.5 8.8 13.2 12.0 20.1 11.0 5.5 6.2 18.5 40.5 2.8 19.2 30.4 53.3 0.9 40.7 4.3 7.7 6.3 9.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.3 9.0 1.7 7.2 0.8 0.4 0.0 3.6 1.3 2.9 0.0 0.0 0.0 2.6 0.0 0.2 3.4 0.7 0.8 0.0 13.2 0.0 3.7 49.9 0.5 0.0 0.0 17.6 3.7 0.0 0.0 0.0 0.0 0.3 1.8 2.5 0.0 0.4 5.7 2.0 0.0 0.0 0.1 0.1 0.5 70.2 23.2 103.0 12.9 0.0 7.7 0.3 0.0 2.8 7.2 0.2 0.2 3.9 0.0 0.3 2.6 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 123.1 135.5 82.9 82.2 116.9 56.3 56.9 70.7 53.0 53.3 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 56.1" "Cell line enhanced" "Detected in many" "ASC diff: 28.8;ASC TERT1: 20.5;HSkMC: 37.0;SiHa: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 15.5;myeloid DC: 11.9" "Group enriched" "Detected in many" 5 "dendritic cells: 11.9;monocytes: 15.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles 5000000 Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favourable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 56.1 6.6 3.8 5.4 7.0 1.1 37.2 1.2 4.9 6.5 12.9 13.2 0.9 1.6 10.7 6.1 4.1 6.4 6.5 2.9 5.3 3.0 22.1 11.6 24.1 13.0 10.9 4.3 7.5 7.8 3.2 1.0 27.9 5.5 6.2 10.8 2.7 3.2 1.7 8.2 13.0 3.7 2.5 6.7 11.4 5.9 5.8 9.3 1.1 5.1 3.5 4.5 4.4 4.4 2.8 11.9 1.3 15.5 0.3 1.3 4.7 0.0 1.5 0.0 0.0 28.8 20.5 0.3 3.8 0.4 0.6 0.9 1.2 1.6 0.2 3.8 0.5 0.0 0.5 1.0 1.6 0.0 1.0 0.0 6.2 0.1 0.1 0.4 0.7 37.0 0.2 0.4 0.8 0.0 0.0 0.0 2.9 0.6 0.0 0.2 0.6 2.0 1.1 0.2 0.0 2.9 2.2 0.1 0.0 27.1 4.2 3.2 0.4 10.1 0.1 0.5 3.1 0.2 0.0 0.1 0.1 4.9 1.7 5.1 2.3 0.3 15.5 0.1 0.1 10.2 0.0 1.4 1.2 0.0 11.9 2.8 0.7 0.1 1.3 0.3 4.7 0.8 1.3 4.7 3.8 7.0 1.2 4.9 5.3 3.0 10.9 4.3 5.5 9.3 CPN1 ENSG00000120054 "Carboxypeptidase N subunit 1" P15169 10 100042193-100081877 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 127 "liver: 76.8" "Cell line enriched" "Detected in some" 17 "SK-MEL-30: 55.2" "Group enriched" "Detected in some" 12 "liver cancer: 26.6;melanoma: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" 22000000000 "unprognostic (2.97e-2)" "unprognostic (2.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (6.75e-2)" "unprognostic (2.93e-2)" "unprognostic (5.26e-2)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CPPED1 "CSTP1, FLJ11151" ENSG00000103381 "Calcineurin like phosphoesterase domain containing 1" Q9BRF8 16 12659799-12804017 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 93.6" "Cell line enhanced" "Detected in many" "Hep G2: 44.4;HMC-1: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 93.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040938, HPA041970" Uncertain Supported "Plasma membrane,Cytosol" 380000 Cytosol "Plasma membrane" "HPA040938: AB_10673443, HPA041970: " "prognostic unfavourable (9.72e-4)" "unprognostic (1.70e-1)" "unprognostic (2.04e-3)" "unprognostic (1.05e-2)" "unprognostic (1.13e-3)" "unprognostic (3.86e-2)" "unprognostic (1.35e-1)" "unprognostic (8.67e-2)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (6.26e-2)" "unprognostic (3.64e-1)" "prognostic favourable (1.62e-9)" "unprognostic (5.05e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-3)" "unprognostic (2.40e-2)" 10.9 11.5 8.3 14.3 14.3 9.5 8.5 2.7 11.8 9.2 13.8 20.8 7.4 16.3 8.2 6.2 23.1 7.2 8.9 10.7 11.2 9.5 26.2 31.4 10.4 21.2 20.7 7.7 6.4 4.1 4.3 6.5 36.6 17.6 9.1 11.9 10.2 15.1 7.3 6.4 6.8 20.5 10.0 22.1 27.4 8.1 18.2 13.1 5.8 11.1 8.4 16.9 9.8 9.6 1.5 23.1 93.6 43.7 1.9 1.8 14.6 1.5 9.3 1.0 2.4 3.9 8.4 0.1 17.0 4.6 9.2 7.5 4.5 4.8 2.2 17.7 12.4 0.1 0.0 4.2 9.5 5.2 2.6 19.3 1.4 44.4 2.4 0.0 42.0 8.4 0.9 0.8 6.6 13.7 6.7 1.4 22.4 1.9 1.7 8.9 2.8 1.3 3.6 6.0 4.8 13.8 2.9 4.9 3.2 0.0 15.5 6.1 3.3 4.2 20.4 13.2 2.7 0.0 0.0 0.0 0.3 3.5 2.9 9.8 2.8 6.1 30.6 19.3 1.3 43.7 1.1 1.5 1.1 1.4 23.1 1.0 0.3 0.8 93.6 1.9 40.6 5.6 1.8 14.6 8.3 14.3 2.7 11.8 11.2 9.5 20.7 7.7 17.6 13.1 CTDNEP1 "DULLARD, HSA011916, NET56" ENSG00000175826 "CTD nuclear envelope phosphatase 1" O95476 17 7243591-7252491 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 140.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037439, HPA066466" Uncertain Approved "Lipid droplets" "Lipid droplets" "HPA037439: AB_10601264, HPA066466: " "unprognostic (7.11e-2)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "prognostic favourable (6.45e-4)" "unprognostic (3.12e-1)" "unprognostic (2.13e-1)" "unprognostic (4.61e-2)" "unprognostic (1.50e-2)" "unprognostic (2.98e-1)" "unprognostic (9.90e-2)" "prognostic favourable (1.81e-4)" "unprognostic (3.37e-1)" "unprognostic (2.77e-3)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (9.97e-2)" "unprognostic (2.02e-2)" 27.1 23.1 21.4 22.4 21.0 24.2 38.8 21.8 26.6 25.3 24.8 26.6 16.7 20.8 31.2 22.8 26.6 27.3 18.8 29.0 21.5 12.9 23.8 20.6 26.5 39.4 24.7 17.1 31.1 27.9 30.7 26.1 30.4 20.5 25.2 27.9 20.4 23.0 23.8 140.1 35.5 30.9 26.7 25.6 38.3 24.3 26.6 24.3 43.8 26.0 31.5 34.1 22.4 26.7 13.0 17.3 18.3 11.8 7.2 11.2 3.8 38.1 57.2 32.2 34.5 50.4 62.1 24.4 28.6 48.0 46.2 39.8 27.3 26.7 35.4 30.5 51.1 32.0 42.2 44.1 51.6 52.5 35.8 24.7 38.4 46.9 46.8 28.1 46.8 50.0 53.7 52.8 56.4 49.1 22.0 26.3 43.3 24.1 31.3 30.1 22.4 24.3 38.1 28.7 28.2 36.7 20.1 12.4 35.5 22.8 22.9 30.5 21.5 23.2 27.9 33.7 29.0 26.9 53.7 22.7 19.8 18.2 43.4 38.8 34.8 6.3 11.8 18.3 10.5 11.7 8.5 13.0 10.1 11.0 8.4 12.4 7.8 11.2 15.6 7.2 7.7 17.3 9.6 3.8 21.4 21.0 21.8 26.6 21.5 12.9 24.7 17.1 20.5 24.3 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679801-79756623 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 6.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: " "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favourable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favourable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 10.6 8.2 6.2 12.8 9.5 21.8 9.5 7.5 12.2 7.9 12.0 14.4 5.3 13.4 11.9 9.3 11.4 9.8 10.0 6.6 6.8 5.7 8.9 13.4 10.2 14.4 12.3 5.1 7.7 13.4 4.6 7.9 10.6 9.1 9.1 6.2 8.4 10.6 8.3 12.1 20.9 13.8 8.2 6.8 15.3 12.2 27.2 10.6 26.2 9.4 8.8 14.8 11.4 8.9 0.7 1.5 6.4 1.0 2.4 2.0 0.5 8.0 9.0 5.0 7.2 4.0 3.4 16.7 5.4 4.0 5.0 4.9 5.9 5.1 10.3 2.5 3.5 9.9 4.3 5.7 2.1 9.5 7.7 5.3 4.5 8.0 5.9 23.4 13.2 5.6 5.4 5.3 2.5 6.0 6.5 5.3 1.9 7.2 15.7 18.4 7.9 12.1 12.2 6.6 12.4 3.7 8.4 7.8 8.1 6.4 6.4 8.6 5.2 13.8 8.1 8.6 12.5 3.4 5.8 4.4 16.5 10.2 7.3 11.8 6.0 0.0 1.0 6.4 1.3 0.9 1.1 0.7 1.0 2.0 1.5 0.4 1.3 0.7 2.7 2.4 0.9 0.2 0.3 0.5 6.2 9.5 7.5 12.2 6.8 5.7 12.3 5.1 9.1 10.6 CTDSP1 "NLIIF, SCP1" ENSG00000144579 "CTD small phosphatase 1" Q9GZU7 2 218398256-218405941 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062654 Supported Nucleoplasm Nucleoplasm "HPA062654: " "unprognostic (1.97e-2)" "unprognostic (4.02e-2)" "unprognostic (1.67e-3)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (3.90e-2)" "unprognostic (8.69e-2)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (3.70e-1)" "unprognostic (1.79e-1)" "unprognostic (2.58e-1)" "unprognostic (6.67e-2)" "unprognostic (2.62e-1)" "unprognostic (7.01e-2)" "unprognostic (1.57e-1)" 32.9 22.5 15.9 21.9 13.9 19.9 41.1 12.2 16.4 34.8 30.7 27.6 31.8 24.2 34.5 30.7 31.3 30.9 43.4 25.9 15.5 8.6 34.1 47.5 30.2 33.2 15.0 13.1 44.9 50.8 28.8 12.6 71.3 15.9 41.5 19.8 35.4 34.3 31.5 23.2 30.5 41.3 33.7 12.4 39.1 34.2 15.1 16.1 33.2 41.0 27.2 29.9 32.5 28.4 3.4 6.6 29.3 12.4 6.7 11.0 7.5 10.1 13.1 7.8 25.5 21.1 19.7 29.3 13.7 19.8 13.3 11.5 17.1 25.5 6.2 11.9 24.2 20.9 11.5 16.5 6.8 22.0 9.0 23.5 16.1 22.9 25.4 14.4 32.9 22.4 20.2 10.1 11.4 19.5 19.0 22.1 14.0 28.5 12.6 42.1 5.4 13.5 17.5 10.9 13.3 16.9 12.6 5.2 12.9 12.0 26.1 12.9 14.4 34.7 17.0 21.2 12.9 16.1 6.0 14.2 9.2 14.5 18.8 13.7 11.7 20.3 12.4 29.3 11.0 10.2 7.1 3.4 6.7 7.0 6.6 3.2 4.3 5.7 24.5 6.7 10.4 2.3 5.6 7.5 15.9 13.9 12.2 16.4 15.5 8.6 15.0 13.1 15.9 16.1 CTDSP2 "OS4, PSR2, SCP2" ENSG00000175215 "CTD small phosphatase 2" O14595 12 57819927-57846739 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "RH-30: 165.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052607 Uncertain Approved Nucleoplasm,Mitochondria Nucleoplasm Mitochondria "HPA052607: " "unprognostic (7.09e-2)" "unprognostic (2.45e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (4.39e-1)" "unprognostic (5.57e-2)" "unprognostic (1.05e-3)" "unprognostic (2.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" "unprognostic (1.12e-1)" "unprognostic (4.15e-1)" "unprognostic (7.38e-3)" "unprognostic (5.50e-2)" "unprognostic (6.50e-2)" "unprognostic (2.18e-1)" "unprognostic (3.11e-1)" 44.5 43.6 28.2 31.6 34.8 17.6 39.6 57.1 33.4 49.0 48.4 36.7 47.7 24.4 50.4 32.9 38.0 41.9 37.7 34.6 31.2 16.5 32.8 32.6 51.3 31.3 37.1 19.9 52.5 53.9 33.7 25.4 42.9 31.0 40.5 38.6 29.3 45.8 60.9 48.8 39.9 36.1 44.1 25.7 38.1 43.1 21.0 40.9 62.9 40.1 32.8 33.9 46.1 63.0 7.3 9.3 18.7 9.7 8.2 11.5 7.1 10.8 4.7 22.6 14.4 20.4 35.2 7.5 11.7 22.3 11.7 10.4 6.0 17.7 13.3 13.5 25.0 8.7 9.4 11.4 12.3 4.5 4.0 18.4 7.2 4.8 19.0 8.3 10.7 33.6 12.2 10.6 9.0 18.2 9.6 23.6 5.8 5.0 8.9 5.0 11.5 6.0 11.9 165.7 17.4 9.1 15.8 4.2 9.4 16.4 9.4 14.1 17.1 14.6 14.6 10.4 11.4 11.7 4.1 7.0 7.5 16.0 11.7 7.7 8.0 11.5 9.7 14.7 6.9 9.0 8.2 7.3 9.9 8.0 9.3 6.5 11.5 8.7 18.7 8.2 7.7 7.7 6.4 7.1 28.2 34.8 57.1 33.4 31.2 16.5 37.1 19.9 31.0 40.9 CTDSPL "C3orf8, HYA22, PSR1, RBSP3, SCP3" ENSG00000144677 "CTD small phosphatase like" O15194 3 37861960-37984469 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048325 Approved Approved Nucleoplasm,Vesicles 10000 Vesicles Nucleoplasm "HPA048325: " "unprognostic (7.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (6.48e-3)" "unprognostic (1.73e-1)" "unprognostic (3.35e-2)" "unprognostic (1.66e-3)" "unprognostic (4.30e-2)" "unprognostic (1.96e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-3)" "unprognostic (1.20e-1)" "prognostic favourable (6.22e-14)" "unprognostic (3.48e-2)" "unprognostic (6.84e-2)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" 12.8 6.3 11.1 7.8 12.4 5.6 22.0 30.2 14.1 15.5 19.9 8.0 25.7 9.3 14.5 18.3 16.8 12.2 37.2 18.9 13.1 5.9 26.7 13.3 19.0 4.9 7.8 9.9 13.7 10.2 8.3 9.4 20.6 6.9 17.5 20.3 15.6 45.5 22.4 12.5 34.8 11.2 21.3 8.1 11.3 19.7 8.1 8.3 2.9 10.0 13.9 6.9 19.6 21.7 0.0 0.2 1.1 0.5 0.0 0.5 5.6 15.5 6.8 2.8 8.8 11.0 15.9 20.9 10.7 13.5 7.4 8.8 9.8 12.8 0.0 6.6 13.2 13.0 6.9 20.3 6.0 0.0 5.4 9.5 7.2 22.1 10.1 0.0 2.3 8.2 49.9 7.8 9.4 10.4 3.0 0.0 12.3 4.9 3.9 0.0 11.5 1.0 4.3 5.4 0.1 23.8 10.4 2.3 7.4 5.9 10.6 11.9 10.2 2.6 8.2 5.4 7.5 10.0 6.7 0.2 0.0 0.0 6.0 5.3 9.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 1.1 0.0 0.0 0.0 0.0 5.6 11.1 12.4 30.2 14.1 13.1 5.9 7.8 9.9 6.9 8.3 CTRB1 CTRB ENSG00000168925 "Chymotrypsinogen B1" P17538 16 75219000-75226338 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2272 "pancreas: 1908.8" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 4.9;U-2 OS: 2.4;U-251 MG: 1.6" "Cancer enriched" "Detected in some" 1905 "pancreatic cancer: 962.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" "unprognostic (1.76e-1)" "unprognostic (2.62e-1)" "unprognostic (3.55e-1)" "unprognostic (1.57e-1)" "unprognostic (5.22e-2)" "unprognostic (4.43e-3)" "unprognostic (2.96e-1)" "unprognostic (1.17e-2)" 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.8 1908.8 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.2 1.6 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CTRB2 ENSG00000168928 "Chymotrypsinogen B2" Q6GPI1 16 75204096-75207185 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5240 "pancreas: 3761.5" "Cell line enhanced" "Detected in some" "EFO-21: 5.0;HDLM-2: 1.9;U-2 OS: 9.0;U-251 MG: 1.9;U-266/84: 2.6;U-698: 2.4" "Cancer enriched" "Detected in single" 1696 "pancreatic cancer: 540.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" "unprognostic (9.41e-4)" "unprognostic (2.20e-1)" "unprognostic (1.28e-2)" "unprognostic (2.10e-1)" "unprognostic (2.92e-2)" "unprognostic (2.77e-1)" "unprognostic (5.95e-2)" "unprognostic (9.56e-2)" "unprognostic (3.54e-3)" "unprognostic (7.06e-2)" "unprognostic (2.17e-1)" "unprognostic (7.57e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 3761.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.0 0.0 1.9 0.1 2.6 2.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 CTRC "CLCR, ELA4" ENSG00000162438 "Chymotrypsin C" Q99895 1 15438439-15449242 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 417 "pancreas: 1443.7" "Cell line enhanced" "Detected in some" "A-431: 3.6" "Cancer enriched" "Detected in some" 168 "pancreatic cancer: 236.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.4" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA046920 Enhanced "Secreted to digestive system" "HPA046920: " "unprognostic (2.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (8.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (2.94e-2)" "unprognostic (7.60e-2)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-11)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "unprognostic (5.99e-3)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 1443.7 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.4 3.4 0.7 1.5 0.6 0.1 3.6 0.6 0.5 0.7 0.2 0.0 0.2 0.3 0.4 0.0 0.0 0.0 1.7 0.5 1.1 0.0 0.5 0.0 0.1 0.2 1.1 0.5 0.4 0.3 0.1 0.9 0.2 1.7 0.2 0.0 0.0 0.0 0.0 0.1 1.7 0.2 0.5 1.0 1.6 0.4 0.0 0.5 0.1 0.3 0.0 0.1 0.4 1.0 0.4 0.2 0.2 0.3 0.1 0.9 0.4 1.4 0.9 0.2 0.8 1.6 0.3 0.8 0.8 0.3 3.4 0.4 0.4 0.4 0.2 0.2 0.3 0.3 0.6 0.1 1.1 0.3 0.4 1.7 1.5 0.7 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898820 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 125.7" "Cell line enhanced" "Detected in all" "ASC diff: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068" Enhanced Enhanced Vesicles "Intracellular and membrane" 18000000 Vesicles "CAB024930: , HPA031068: AB_10601205" "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavourable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" 29.0 125.7 12.0 22.8 19.5 22.1 35.3 11.4 30.0 14.1 50.6 17.4 16.2 29.4 18.2 19.3 20.7 12.7 28.0 32.6 11.5 11.6 88.2 43.8 28.4 38.9 12.3 16.1 23.9 19.2 28.3 16.5 47.7 15.7 18.2 50.5 30.1 20.5 15.1 19.3 28.2 40.6 19.6 11.9 38.8 19.7 14.3 11.2 8.0 18.1 24.9 22.4 23.3 18.7 7.0 16.6 81.1 46.1 12.0 31.2 50.0 14.4 14.9 2.8 12.7 116.2 60.2 6.4 20.8 55.4 22.8 29.7 27.9 38.9 3.1 24.1 38.9 23.1 7.5 14.0 14.3 6.0 7.0 8.2 10.4 48.6 25.9 13.0 33.9 47.8 16.9 14.7 3.3 24.8 8.1 47.8 24.7 29.7 3.3 12.0 2.8 35.4 5.2 14.5 17.2 18.2 12.7 5.6 5.3 34.6 60.6 58.0 14.8 18.7 22.8 45.8 10.7 25.9 16.3 23.6 29.7 2.2 82.5 17.3 18.8 60.6 46.1 81.1 7.5 26.6 31.2 7.0 12.9 13.2 16.6 3.6 4.7 6.9 24.7 12.0 17.7 6.6 23.9 50.0 12.0 19.5 11.4 30.0 11.5 11.6 12.3 16.1 15.7 11.2 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869448 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 297.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 237.0;fHDF/TERT166: 137.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 53.1;classical monocyte: 127.4;intermediate monocyte: 97.0;myeloid DC: 68.0;non-classical monocyte: 54.7;plasmacytoid DC: 95.4" "Group enriched" "Detected in all" 5 "dendritic cells: 95.4;granulocytes: 53.1;monocytes: 127.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" 130000000 Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favourable (5.76e-4)" "prognostic unfavourable (9.02e-4)" 227.9 42.1 19.6 67.2 24.4 14.7 67.6 14.9 31.4 76.7 49.1 30.1 22.7 29.9 53.2 44.8 54.2 52.4 43.6 120.7 18.3 23.7 95.6 167.8 94.3 175.1 29.1 16.5 44.2 31.6 13.8 21.6 68.7 24.8 42.6 27.9 33.8 63.7 33.6 41.3 22.8 51.2 51.1 35.9 116.4 26.7 21.5 20.4 18.1 297.0 25.9 38.4 56.8 62.2 7.9 95.4 53.1 127.4 5.3 17.1 108.5 6.4 29.1 3.7 16.0 65.8 74.1 11.6 121.4 237.0 42.5 50.4 13.9 37.9 0.1 17.6 137.7 35.4 5.1 33.5 26.9 3.1 5.0 9.4 3.4 34.1 67.0 2.1 7.0 81.1 45.7 38.4 34.4 83.1 7.8 21.5 35.3 5.1 0.8 3.4 3.1 9.8 3.3 3.8 16.4 12.9 10.1 1.6 9.5 14.0 7.6 63.3 12.3 6.3 115.1 72.3 24.5 23.1 22.6 21.4 15.5 0.5 82.9 8.1 33.8 53.1 127.4 16.3 5.2 97.0 7.2 7.9 17.1 5.8 68.0 6.1 9.6 4.1 18.5 5.3 54.7 95.4 13.4 108.5 19.6 24.4 14.9 28.0 18.3 23.7 29.1 16.5 24.8 20.4 CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88293592-88337787 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 218.6" "Cell line enhanced" "Detected in all" "BJ hTERT+: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" 19000000 Vesicles "CAB025364: , HPA066610: , HPA068434: " "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavourable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favourable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" 40.7 20.5 6.7 44.5 10.6 12.0 35.3 1.5 5.6 14.0 25.3 7.1 6.2 20.4 16.1 24.0 21.8 16.7 36.6 53.3 6.8 6.5 62.7 18.1 110.1 218.6 12.5 3.6 11.0 24.8 3.8 17.3 43.4 9.4 13.8 33.1 27.0 35.1 5.8 10.0 11.7 28.5 14.2 14.6 86.6 13.5 10.8 9.2 19.5 17.7 25.3 30.0 30.2 16.9 8.5 75.9 52.5 92.6 34.7 42.4 31.2 11.2 11.5 4.5 9.4 12.2 33.0 30.2 77.1 112.0 44.0 31.8 31.2 51.8 17.5 41.0 41.8 18.2 7.0 32.6 35.2 30.8 12.7 22.8 31.9 35.1 16.2 28.9 15.4 45.9 23.1 33.9 69.6 43.2 20.7 21.1 5.3 2.1 13.0 40.0 23.6 35.7 17.0 4.7 31.0 56.6 18.9 1.2 9.5 13.0 17.2 10.1 3.8 19.8 21.0 3.0 27.3 20.9 48.9 9.0 12.8 17.7 8.0 61.1 16.7 12.5 32.5 52.5 42.4 69.3 36.5 8.5 19.5 37.8 35.1 4.6 9.9 23.8 37.2 34.7 92.6 75.9 28.4 31.2 6.7 10.6 1.5 5.6 6.8 6.5 12.5 3.6 9.4 9.2 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 215.7;SK-BR-3: 206.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB000109, HPA003001" Supported "Secreted to blood" 540000000 "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavourable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favourable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 151.9 148.7 21.4 32.8 27.0 83.7 67.7 18.6 47.4 56.3 59.3 41.4 41.9 61.6 25.9 48.2 46.2 34.2 90.0 86.0 25.3 27.6 150.5 163.5 102.6 81.1 49.6 25.7 41.2 62.3 21.3 24.9 56.1 42.8 33.9 33.7 234.4 64.1 42.3 76.2 50.8 90.9 23.3 36.7 87.6 47.0 29.8 29.7 21.1 36.3 42.9 41.4 64.6 43.5 4.9 22.7 51.1 83.8 28.4 26.1 58.7 15.6 42.4 4.9 20.4 62.1 21.2 7.9 11.6 36.2 15.6 18.5 10.5 215.7 3.8 30.1 29.9 84.4 7.1 13.0 4.3 16.1 15.4 5.8 8.0 13.2 65.5 13.3 61.6 34.2 57.0 8.4 15.5 11.4 6.9 23.2 27.6 57.7 3.4 7.5 11.6 17.0 4.9 6.0 14.1 55.0 49.0 6.8 6.7 13.8 206.2 39.1 80.7 18.4 14.3 47.5 7.3 6.5 18.6 32.0 40.1 2.4 69.2 36.1 39.8 29.0 83.8 25.2 26.1 47.6 15.1 4.9 12.2 18.3 22.7 3.2 14.3 18.3 51.1 28.4 38.5 19.2 13.5 58.7 21.4 27.0 18.6 47.4 25.3 27.6 49.6 25.7 42.8 29.7 CTSE ENSG00000196188 "Cathepsin E" P14091 1 206009264-206023909 "Enzymes, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 57.9;intestine: 47.3;stomach 1: 153.0" "Group enriched" "Detected in some" 7 "BEWO: 14.8;RT4: 28.1" "Group enriched" "Detected in many" 8 "lung cancer: 68.8;pancreatic cancer: 297.4;stomach cancer: 200.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012940, CAB032687" Enhanced "Intracellular and membrane" "CAB032687: AB_637901, HPA012940: " "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-2)" "unprognostic (2.72e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-3)" "unprognostic (1.45e-1)" "unprognostic (3.29e-2)" "unprognostic (2.87e-2)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "unprognostic (6.37e-3)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (2.61e-2)" "prognostic favourable (5.26e-5)" 0.2 0.1 0.1 3.7 0.1 3.0 0.1 0.1 0.1 0.1 47.3 0.3 0.8 29.3 0.1 0.7 0.6 0.5 57.9 0.3 0.1 0.1 0.2 0.2 24.9 0.0 0.1 0.0 0.1 2.2 0.0 0.5 0.0 0.1 1.3 3.2 0.0 0.1 0.0 0.1 0.1 29.7 0.0 0.1 0.2 153.0 0.1 0.0 0.3 4.2 0.0 1.1 1.8 0.4 0.2 0.7 0.0 0.4 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.5 0.6 0.0 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.7 2.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.9 0.5 0.0 0.2 0.0 0.5 0.6 28.1 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563463-66568841 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HSkMC: 28.2;SK-MEL-30: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cells: 7.5;T-cells: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431, HPA055610" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" 3600000 Cytosol "Vesicles, Plasma membrane" "CAB002141: AB_563471, HPA031431: , HPA055610: " "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-3)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.76e-2)" "unprognostic (3.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.69e-2)" "unprognostic (9.12e-2)" "prognostic favourable (8.92e-7)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (2.42e-1)" 28.1 29.4 24.7 8.0 29.0 1.8 31.1 38.4 47.1 37.3 23.8 32.6 25.2 5.8 38.1 29.8 12.9 34.3 37.3 34.5 25.3 20.5 29.8 45.4 17.3 8.5 28.0 26.0 68.2 23.1 42.6 15.9 20.2 25.4 32.3 8.1 35.0 35.5 37.8 35.8 19.7 9.4 34.6 22.4 10.4 17.8 37.1 30.1 0.8 18.6 14.2 6.3 22.2 21.5 2.1 1.1 0.5 0.7 7.5 9.7 2.4 0.1 9.2 5.0 12.9 21.3 8.6 3.6 6.5 16.5 6.8 4.8 0.0 8.2 0.0 11.0 14.2 0.9 8.5 2.8 3.6 2.2 0.0 0.3 3.8 0.0 11.9 0.1 5.0 28.2 9.6 1.5 1.1 4.3 2.8 1.5 8.5 1.9 0.1 1.1 0.6 3.4 0.0 1.9 1.6 6.1 0.2 6.0 6.4 17.4 2.0 52.3 13.2 0.8 2.8 2.7 2.7 3.2 0.6 8.8 0.1 0.0 6.5 0.1 4.1 0.0 0.7 0.4 6.5 0.7 7.0 2.0 5.6 7.3 0.8 2.1 9.7 5.5 0.5 7.5 0.3 1.1 1.7 2.4 24.7 29.0 38.4 47.1 25.3 20.5 28.0 26.0 25.4 30.1 CTSG CG ENSG00000100448 "Cathepsin G" P08311 14 24573522-24576260 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "bone marrow: 450.3" "Cell line enriched" "Detected in some" 7 "THP-1: 437.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.5;memory CD8 T-cell: 3.5;myeloid DC: 5.1;naive CD8 T-cell: 1.8;neutrophil: 7.1;NK-cell: 5.2;plasmacytoid DC: 5.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "CAB000110, HPA047737" Enhanced "Intracellular and membrane" 67000 "CAB000110: , HPA047737: " "unprognostic (1.67e-1)" "unprognostic (2.57e-2)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "prognostic favourable (1.57e-4)" "unprognostic (4.05e-2)" "unprognostic (4.13e-2)" "unprognostic (3.06e-1)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" "unprognostic (1.63e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "prognostic unfavourable (8.91e-4)" 15.1 0.5 0.0 6.0 0.0 450.3 6.0 0.0 0.6 10.0 5.1 0.0 2.8 1.1 6.2 19.7 6.4 0.8 16.7 23.4 0.0 0.0 2.1 2.0 9.2 3.7 0.0 0.0 1.5 3.4 0.8 0.5 3.0 0.0 8.2 3.2 2.6 6.3 6.9 1.1 19.5 8.9 14.9 0.0 10.7 3.2 2.8 0.0 15.6 0.5 12.0 5.1 2.9 3.3 0.0 5.7 7.1 6.5 5.2 3.5 12.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 437.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 64.9 0.0 0.0 6.5 0.0 1.1 1.0 0.0 0.0 1.0 3.5 5.1 0.0 0.0 1.8 7.1 5.2 0.0 5.7 0.0 12.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 82.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.5;HaCaT: 31.0;RT4: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 42.8" "Group enriched" "Detected in all" 5 "B-cells: 20.6;dendritic cells: 41.2;monocytes: 42.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" 10000000 "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favourable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 16.7 10.6 9.5 24.2 7.0 5.4 23.9 4.5 9.8 25.1 11.4 17.7 14.7 10.6 10.3 17.1 7.8 13.1 29.2 16.5 14.8 6.7 66.7 18.7 82.6 65.4 12.1 11.6 14.6 25.8 12.3 6.5 7.7 9.4 18.6 6.6 6.7 15.4 15.9 7.0 13.5 16.6 9.8 10.8 20.3 15.6 6.7 15.7 6.6 8.5 4.8 34.8 39.6 13.5 20.6 41.2 1.4 42.8 1.3 7.6 27.3 16.0 1.1 0.4 4.7 1.1 0.0 5.2 1.6 0.6 2.8 1.5 7.0 42.5 5.6 1.7 0.1 31.0 2.0 7.7 2.3 23.6 0.1 0.1 0.2 16.2 1.6 0.0 1.0 0.8 2.2 0.0 0.0 0.2 11.4 0.0 3.8 1.7 3.6 9.8 1.2 0.3 0.0 0.3 0.9 9.8 118.0 0.5 1.1 6.9 3.9 9.6 1.5 5.3 2.2 0.0 1.0 0.0 0.7 0.1 12.2 3.1 0.0 10.3 1.7 0.0 42.8 0.4 1.4 28.3 7.6 20.6 4.1 2.1 41.2 12.0 0.4 0.7 1.4 1.3 17.0 4.2 3.1 27.3 9.5 7.0 4.5 9.8 14.8 6.7 12.1 11.6 9.4 15.7 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150796208-150808323 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 104.1" "Group enriched" "Detected in some" 8 "ASC diff: 200.2;ASC TERT1: 73.3;BJ hTERT+: 161.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 6.7" "Lineage enriched" "Detected in many" 6 "monocytes: 6.7" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" Vesicles "HPA050346: " "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavourable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 104.1 2.4 1.2 6.5 1.6 1.3 79.3 2.4 2.3 70.6 23.6 2.2 10.1 2.7 72.5 25.9 26.5 12.5 53.4 14.7 1.1 1.1 3.4 1.8 8.7 10.4 1.1 1.7 25.4 2.9 0.3 3.0 30.6 2.6 24.2 11.5 56.0 10.9 6.8 19.9 44.0 11.0 26.9 2.0 5.6 8.6 24.1 0.9 1.1 7.1 13.2 10.7 38.0 48.2 0.1 1.0 1.0 6.7 0.5 1.2 1.8 0.1 0.1 0.3 0.3 200.2 73.3 0.2 5.7 161.8 0.4 0.8 0.0 0.1 0.1 0.2 11.1 0.2 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.0 1.0 0.1 0.4 14.6 0.5 4.5 0.1 0.6 0.0 0.5 0.4 0.3 0.0 0.7 1.1 0.1 0.0 0.1 0.0 0.4 0.1 0.1 0.6 0.3 0.0 3.0 0.2 0.2 0.4 0.2 0.1 0.2 0.2 0.6 0.5 1.1 17.0 0.0 0.9 0.0 6.7 1.0 0.7 3.4 0.2 0.0 0.6 0.2 0.4 0.1 0.3 0.5 0.6 0.5 2.0 1.0 1.2 1.8 1.2 1.6 2.4 2.3 1.1 1.1 1.1 1.7 2.6 0.9 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87725519-87731393 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 237.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 198.5;HSkMC: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "intermediate monocyte: 31.0;non-classical monocyte: 44.3" "Lineage enriched" "Detected in many" 10 "monocytes: 44.3" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" 17000000 "Golgi apparatus" Vesicles "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavourable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavourable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favourable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 60.3 21.5 10.4 27.2 24.6 18.4 23.3 6.9 12.3 14.8 23.2 14.1 13.7 9.0 24.1 22.3 11.4 25.7 20.7 37.7 10.7 11.4 65.4 98.0 53.1 80.5 18.9 7.7 25.0 14.3 18.8 18.0 237.0 18.4 19.4 13.0 23.2 22.0 23.5 29.3 9.1 12.0 36.6 16.1 108.1 17.5 14.1 15.7 6.8 19.2 9.4 10.1 41.3 26.5 0.0 1.7 0.1 44.3 0.0 4.3 2.4 6.3 36.8 2.5 4.3 46.3 198.5 15.4 20.5 59.7 17.6 22.1 3.5 5.9 0.0 9.6 26.5 5.4 3.3 6.6 14.5 0.1 3.2 1.1 10.4 8.6 30.0 0.0 4.4 91.8 11.2 28.8 11.2 13.8 11.9 0.0 25.3 10.6 0.0 0.7 4.9 7.0 1.5 1.5 0.0 12.3 3.3 3.7 4.5 4.3 9.6 23.5 1.1 7.3 21.7 15.8 8.6 57.5 8.6 1.6 5.9 0.0 57.8 0.0 5.2 0.1 3.5 0.1 0.0 31.0 0.0 0.0 1.8 0.0 1.7 0.0 4.3 0.3 0.1 0.0 44.3 0.1 0.3 2.4 10.4 24.6 6.9 11.7 10.7 11.4 18.9 7.7 18.4 15.7 CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155924118-155953917 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 12.3;HSkMC: 14.6;Karpas-707: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" 24000 "HPA002041: AB_1078408" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (9.10e-3)" "unprognostic (2.55e-1)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (4.87e-3)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" 13.7 16.4 11.9 12.6 12.0 1.8 14.9 3.7 12.4 16.0 18.5 11.6 10.2 13.3 19.3 27.3 10.8 15.6 16.9 19.7 9.7 8.6 21.2 41.6 26.4 19.4 10.2 6.7 16.3 10.7 13.6 9.4 18.7 9.7 16.1 9.8 24.0 13.8 16.8 5.9 6.2 27.5 14.4 11.4 19.3 10.8 9.0 7.7 5.5 17.1 10.2 10.3 12.4 12.5 7.0 8.9 5.3 14.8 12.0 10.9 8.9 0.3 0.2 1.5 1.6 5.6 12.3 0.0 3.5 7.1 1.3 1.8 0.0 4.6 0.0 0.7 2.3 0.0 0.0 0.3 0.9 5.2 0.1 0.4 0.0 0.0 5.9 0.7 0.1 14.6 1.3 0.8 0.6 1.2 0.0 27.5 4.1 0.3 0.3 0.1 0.3 0.2 1.6 0.3 1.7 5.3 2.3 0.2 1.7 0.8 2.9 1.0 1.5 1.0 2.0 4.3 0.2 0.4 1.1 3.1 0.0 0.0 7.8 0.0 5.8 5.3 12.0 0.8 7.9 14.8 10.9 5.8 6.1 7.3 8.9 7.0 6.7 6.8 0.5 12.0 10.7 8.3 6.8 8.9 11.9 12.0 3.7 12.4 9.7 8.6 10.2 6.7 9.7 7.7 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730196-150765957 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 171.4;lymphoid tissue: 111.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 21.1;HMC-1: 50.3;U-698: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 171.4;intermediate monocyte: 151.2;myeloid DC: 43.5;neutrophil: 94.5;non-classical monocyte: 138.5" "Group enriched" "Detected in all" 9 "dendritic cells: 43.5;granulocytes: 94.5;monocytes: 171.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" 19000000 Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 41.6 9.3 6.8 32.3 10.3 30.3 9.7 1.9 6.2 4.7 32.9 6.6 5.6 19.6 3.7 12.9 8.8 10.7 15.9 17.3 6.4 5.1 9.6 21.5 55.8 99.5 12.6 2.3 7.6 6.4 0.4 3.4 14.4 9.3 7.5 33.4 6.5 12.9 3.3 3.5 3.8 38.0 6.8 17.1 111.4 13.8 3.8 9.5 12.9 7.6 4.6 22.8 21.5 5.3 11.1 43.5 94.5 171.4 3.3 5.6 145.4 1.0 3.2 0.0 0.0 0.4 0.3 0.3 0.0 3.2 0.2 0.6 0.0 21.1 14.5 1.6 0.1 0.4 0.0 0.1 0.0 8.1 0.0 6.4 0.1 0.0 0.0 8.7 50.3 0.6 0.0 1.8 0.1 1.2 0.6 12.7 0.4 0.0 0.0 6.2 0.0 0.0 3.6 1.2 17.8 3.9 3.1 0.0 0.1 0.2 0.9 0.3 0.0 17.8 1.7 1.3 0.2 0.0 0.2 8.8 0.8 106.9 7.4 9.4 0.8 1.2 171.4 16.5 3.2 151.2 3.9 11.1 3.9 3.8 43.5 10.2 3.9 3.6 94.5 3.3 138.5 9.4 5.6 145.4 6.8 10.3 1.9 6.2 6.4 5.1 12.6 2.3 9.3 9.5 CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029679-97039643 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 154.7" "Cell line enriched" "Detected in many" 8 "BEWO: 113.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "NK-cell: 4.2;plasmacytoid DC: 15.7" "Group enriched" "Detected in many" 42 "dendritic cells: 15.7;NK-cells: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" 260000 "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favourable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavourable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavourable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavourable (2.39e-4)" 0.7 0.0 0.4 0.6 0.7 0.0 3.5 0.4 1.0 23.0 1.4 2.0 0.4 0.5 1.5 1.5 9.8 0.6 0.5 0.2 0.8 0.6 9.7 0.4 0.6 0.2 1.5 0.7 0.4 1.1 1.1 0.9 8.7 1.6 0.5 1.6 4.3 5.0 0.6 0.5 25.0 0.6 0.2 3.0 0.2 1.1 32.4 1.0 154.7 0.7 6.3 2.7 0.2 9.9 0.2 15.7 0.2 0.0 4.2 0.0 0.1 7.3 2.2 2.5 6.5 0.1 0.0 113.4 0.0 0.0 1.6 1.3 14.9 7.3 0.1 0.6 0.1 14.0 12.1 8.9 2.3 0.0 1.6 0.3 0.7 2.3 0.0 0.0 1.0 0.0 3.0 0.4 0.3 0.5 0.2 0.0 2.9 2.7 0.2 0.1 15.0 2.1 0.0 5.4 0.1 2.2 0.9 0.6 1.1 7.4 2.6 2.6 4.6 0.8 0.0 0.4 7.4 0.1 0.8 1.5 4.0 0.1 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.2 4.2 0.0 15.7 0.0 0.1 0.4 0.7 0.4 1.0 0.8 0.6 1.5 0.7 1.6 1.0 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58995185-59007247 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.2;intermediate monocyte: 2.7;memory B-cell: 1.0;myeloid DC: 3.9;naive B-cell: 1.9;neutrophil: 3.5;non-classical monocyte: 2.9;plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" 85000000 Vesicles "CAB025114: , HPA049876: , HPA053504: " "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavourable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 70.7 27.9 12.4 40.8 20.4 20.7 51.2 14.6 13.5 25.4 52.8 16.0 19.9 40.8 20.6 25.5 20.1 20.7 22.3 50.1 9.8 13.3 34.9 83.7 54.3 61.2 18.8 10.5 29.7 29.0 30.6 27.6 38.6 19.2 28.8 37.8 31.5 40.3 17.7 20.7 12.9 63.6 26.4 22.1 56.5 19.2 13.8 14.9 18.4 42.4 17.5 35.8 29.8 21.5 1.9 3.9 3.5 3.2 0.3 0.6 0.8 27.2 21.2 0.0 0.0 25.0 28.8 15.0 44.9 49.7 34.4 30.8 41.0 45.9 15.0 29.7 118.0 21.8 13.5 42.5 23.6 47.9 1.8 13.7 34.4 0.0 26.2 1.6 47.7 24.5 25.7 15.0 18.0 54.4 9.9 7.6 23.0 0.0 0.1 14.8 1.7 21.2 0.3 0.1 18.0 25.1 6.4 0.4 0.3 34.9 40.4 0.1 18.7 23.2 59.8 0.0 23.2 30.2 0.2 36.2 22.0 2.8 0.4 33.1 0.0 0.0 3.2 0.3 0.6 2.7 0.0 1.0 0.4 0.1 3.9 1.9 0.4 0.1 3.5 0.3 2.9 2.2 0.2 0.8 12.4 20.4 14.6 13.5 9.8 13.3 18.8 10.5 19.2 14.9 CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095" Approved Supported "Nucleoplasm,Centriolar satellite" "Centriolar satellite" Nucleoplasm "CAB011713: AB_731794, HPA050095: " "unprognostic (9.83e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "unprognostic (2.83e-2)" "unprognostic (3.84e-1)" "unprognostic (5.06e-2)" "unprognostic (3.87e-2)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (6.83e-2)" "unprognostic (8.42e-2)" 9.3 16.2 13.9 22.9 26.4 51.1 9.1 14.2 20.9 9.2 10.3 18.8 12.8 10.2 16.1 8.1 15.3 8.5 13.3 12.7 15.7 17.0 9.4 13.2 15.6 30.7 16.3 14.3 11.5 12.2 20.3 27.8 9.8 20.0 11.0 12.7 13.3 12.6 10.9 31.7 12.4 14.2 12.5 16.3 23.4 12.4 22.6 13.7 16.9 16.2 8.0 29.3 14.1 12.6 9.2 10.2 31.4 9.8 13.6 19.1 10.2 9.1 2.9 3.3 3.7 5.3 7.7 3.0 13.6 19.9 14.2 8.4 2.4 4.3 10.6 4.9 13.2 3.6 3.9 8.2 21.1 46.4 6.0 5.3 5.1 1.9 10.6 5.2 24.9 8.4 6.7 17.1 17.9 5.7 2.2 9.2 19.8 1.3 5.1 7.6 3.5 4.8 4.6 6.8 10.1 4.6 3.2 4.3 3.3 11.5 3.9 3.3 3.9 6.6 6.4 24.3 5.5 8.5 5.5 24.3 23.1 11.8 17.8 5.9 5.1 31.4 8.6 20.8 10.7 9.8 12.9 9.2 15.8 14.4 10.2 6.2 14.7 11.4 19.4 13.6 9.5 6.2 19.1 10.2 13.9 26.4 14.2 20.9 15.7 17.0 16.3 14.3 20.0 13.7 DCP2 NUDT20 ENSG00000172795 "Decapping mRNA 2" Q8IU60 5 112976702-113020970 "Enzymes, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 52.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011677, HPA057676" Approved Approved "Nucleoplasm,Cell Junctions,Cytoplasmic bodies" "Nucleoplasm, Cytoplasmic bodies" "Cell Junctions" "CAB011677: AB_731858, HPA057676: " "unprognostic (2.76e-1)" "unprognostic (3.27e-1)" "unprognostic (2.79e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-1)" "unprognostic (3.86e-3)" "prognostic unfavourable (4.84e-4)" "unprognostic (1.87e-1)" "unprognostic (3.64e-2)" "unprognostic (6.26e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-2)" "prognostic unfavourable (2.66e-5)" "unprognostic (8.39e-2)" "unprognostic (2.84e-1)" "unprognostic (3.25e-2)" "unprognostic (5.75e-2)" 8.0 7.5 8.1 16.3 9.5 22.9 15.0 16.8 10.9 9.1 6.6 6.4 6.6 6.3 10.5 6.8 7.4 8.0 6.5 6.1 8.1 8.9 8.1 8.1 13.2 19.8 6.9 6.1 12.8 6.2 7.0 12.2 40.2 8.3 8.1 7.3 6.5 9.6 8.6 8.3 9.8 8.7 7.3 7.4 19.9 6.7 6.8 6.5 52.9 7.0 4.1 20.0 8.7 9.1 5.1 6.5 16.3 8.3 3.9 5.9 3.2 3.6 3.1 14.1 11.3 2.8 3.1 22.8 3.3 2.7 4.2 6.1 14.6 7.8 19.1 5.3 1.9 4.5 16.2 4.5 5.1 5.1 7.1 17.9 2.7 5.8 3.2 10.9 9.3 2.9 3.1 5.1 5.1 7.1 13.2 7.5 3.8 4.6 16.0 11.6 12.2 1.9 15.7 13.4 7.1 6.5 9.3 3.3 7.0 4.6 5.2 6.7 15.4 14.6 4.6 4.7 8.4 2.4 5.0 5.1 11.2 14.6 2.7 15.3 3.6 12.2 7.2 5.5 4.0 7.1 5.5 5.1 4.9 4.2 6.5 3.6 4.6 4.7 16.3 3.9 8.3 3.5 5.9 3.2 8.1 9.5 16.8 10.9 8.1 8.9 6.9 6.1 8.3 6.5 DCPS "HINT-5, HSL1, HSPC015" ENSG00000110063 "Decapping enzyme, scavenger" Q96C86 11 126303752-126345749 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" Hydrolase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039632, HPA058597" Supported Supported Nucleoplasm,Cytosol 1400000 Nucleoplasm Cytosol "HPA039632: AB_10794200, HPA058597: " "unprognostic (1.45e-1)" "unprognostic (5.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.55e-2)" "unprognostic (5.22e-2)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (5.57e-2)" "unprognostic (1.91e-2)" "unprognostic (4.83e-2)" "unprognostic (5.00e-2)" "unprognostic (5.25e-2)" "unprognostic (2.24e-2)" "unprognostic (8.04e-2)" "unprognostic (7.67e-2)" "unprognostic (3.40e-2)" 11.1 13.1 6.8 14.4 8.2 13.5 9.2 8.5 14.5 12.1 10.6 6.8 8.0 7.8 12.4 9.6 14.4 9.9 13.9 10.9 5.5 6.1 13.3 39.6 9.9 18.5 6.3 5.8 11.8 17.2 7.0 9.5 14.1 6.8 12.7 11.7 13.3 17.4 9.4 21.8 11.3 9.7 11.3 7.1 21.9 9.6 13.4 6.5 22.0 12.7 18.5 22.1 15.1 9.8 13.2 39.5 3.2 14.3 7.8 14.6 7.1 10.5 6.6 8.3 13.7 6.4 8.6 6.9 5.6 8.3 8.6 8.7 12.5 21.7 14.4 21.2 8.9 12.4 11.7 17.6 5.7 27.2 6.3 21.1 7.6 10.8 14.0 22.6 19.1 8.7 11.1 10.9 14.9 11.5 8.5 24.7 9.4 15.2 14.4 25.9 5.8 22.7 10.0 12.1 27.4 8.3 11.8 10.7 8.2 17.0 13.9 10.3 23.6 14.2 7.3 13.5 6.3 6.4 10.5 9.9 9.2 14.9 3.9 39.2 33.8 1.7 9.2 3.2 8.8 14.3 8.2 13.2 8.5 9.0 15.4 9.0 6.0 6.8 0.5 7.8 12.6 39.5 14.6 7.1 6.8 8.2 8.5 14.5 5.5 6.1 6.3 5.8 6.8 6.5 DCTD ENSG00000129187 "DCMP deaminase" P32321 4 182890060-182917936 "Enzymes, Predicted intracellular proteins" "Nucleotide biosynthesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035894 Approved Approved Nucleoplasm,Cytosol 13000 "Nucleoplasm, Cytosol" "HPA035894: AB_10673488" "unprognostic (1.26e-1)" "unprognostic (9.80e-3)" "unprognostic (3.15e-2)" "unprognostic (3.78e-3)" "unprognostic (3.13e-3)" "unprognostic (2.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.59e-3)" "unprognostic (2.62e-2)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.20e-1)" "prognostic favourable (1.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.59e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-1)" 24.8 46.2 24.7 19.9 23.8 12.9 27.3 11.6 28.3 27.1 20.4 17.3 22.6 16.4 26.0 20.1 30.9 25.9 40.9 25.8 22.5 22.2 25.7 47.6 25.8 29.4 21.1 20.3 35.9 51.7 28.3 25.3 18.9 21.3 23.7 21.5 30.0 26.4 22.8 24.8 19.4 19.1 27.4 25.6 24.9 27.2 11.8 16.7 15.0 52.9 21.3 26.0 24.5 25.1 31.9 24.8 23.7 25.7 30.8 36.8 22.7 22.4 20.7 21.2 19.5 32.0 43.7 27.7 43.3 38.7 31.1 19.3 21.0 43.7 7.8 10.7 42.2 11.2 15.4 27.0 28.6 37.8 11.7 36.1 12.0 25.0 34.3 35.1 22.6 36.3 28.9 27.3 28.5 26.6 35.8 78.2 41.3 16.3 22.7 21.5 16.8 18.1 24.8 15.1 15.1 25.0 27.0 20.9 13.0 20.5 17.7 20.2 13.6 18.4 30.9 25.9 19.9 12.5 33.0 30.1 16.2 10.0 28.6 23.0 30.4 23.7 22.0 19.7 29.2 25.7 36.8 31.9 25.6 29.7 24.8 21.7 25.5 26.7 1.6 30.8 24.9 19.1 21.9 22.7 24.7 23.8 11.6 28.3 22.5 22.2 21.1 20.3 21.3 16.7 DCTPP1 "CDA03, MGC5627, RS21C6, XTP3TPA" ENSG00000179958 "DCTP pyrophosphatase 1" Q9H773 16 30423619-30430075 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002832 Uncertain Approved Nucleoplasm,Cytosol 270000 "Nucleoplasm, Cytosol" "HPA002832: AB_1080615" "prognostic unfavourable (1.64e-5)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (4.09e-2)" "prognostic unfavourable (6.28e-4)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (4.35e-2)" "unprognostic (2.43e-2)" "unprognostic (3.65e-2)" "prognostic favourable (9.71e-9)" "unprognostic (1.10e-3)" "unprognostic (8.78e-3)" "unprognostic (1.10e-2)" "unprognostic (2.53e-1)" 15.3 15.8 14.8 25.0 13.2 12.5 20.7 15.5 19.2 12.1 37.4 10.3 11.3 20.7 14.1 14.4 19.7 18.9 28.1 23.3 12.1 12.6 27.0 25.3 11.2 27.6 13.3 16.6 16.6 25.2 16.4 7.7 16.3 11.4 15.4 40.3 10.6 20.5 21.1 28.3 16.1 22.9 13.9 11.3 22.5 16.4 9.9 7.8 21.3 22.6 26.0 25.0 13.2 13.0 47.3 30.9 19.0 24.5 23.1 26.2 25.3 26.3 32.4 14.8 19.0 4.2 5.7 13.7 12.7 7.6 19.2 19.6 24.3 22.5 35.7 26.7 7.9 20.7 30.6 24.9 24.0 18.8 48.3 20.8 14.9 31.6 5.4 37.1 32.4 6.5 14.2 21.4 12.3 19.7 26.1 12.6 13.6 46.0 44.1 41.6 19.5 26.2 62.6 16.4 46.5 22.2 17.2 31.5 17.8 8.4 30.2 11.9 26.1 16.0 9.9 14.9 13.3 19.1 22.8 8.3 24.7 45.5 9.8 30.8 17.3 19.0 12.4 11.7 18.8 22.1 26.2 47.3 24.2 21.3 28.7 40.2 21.8 21.0 1.5 23.1 24.5 30.9 24.1 25.3 14.8 13.2 15.5 19.2 12.1 12.6 13.3 16.6 11.4 7.8 DDAH1 DDAH ENSG00000153904 "Dimethylarginine dimethylaminohydrolase 1" O94760 1 85318481-85578363 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 61.6" "Cell line enhanced" "Detected in many" "SH-SY5Y: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006308 Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" 140000 "Plasma membrane, Cytosol" Nucleoli "HPA006308: AB_1847532" "unprognostic (1.44e-2)" "unprognostic (2.43e-1)" "prognostic favourable (5.99e-4)" "unprognostic (6.82e-2)" "unprognostic (1.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.02e-2)" "unprognostic (3.62e-2)" "unprognostic (1.56e-1)" "prognostic favourable (5.21e-6)" "unprognostic (5.37e-2)" "unprognostic (9.06e-2)" "unprognostic (5.81e-2)" "unprognostic (1.56e-2)" 4.3 14.3 43.9 5.8 44.9 0.7 6.6 14.4 37.2 7.7 22.1 20.7 4.3 21.1 6.0 33.8 4.9 18.4 12.2 6.4 29.5 24.1 61.6 39.9 11.8 1.1 24.9 37.0 3.4 13.8 13.0 7.2 3.1 13.8 13.1 21.4 4.1 8.5 6.2 13.8 2.8 19.9 7.4 8.1 4.1 15.6 9.3 11.0 0.0 14.1 1.0 1.2 6.0 3.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 18.7 2.3 6.6 1.2 11.1 9.4 0.8 22.1 13.4 7.9 8.4 26.6 5.0 0.0 9.2 25.0 5.4 23.9 4.6 10.1 0.0 9.2 0.0 6.3 9.2 4.0 17.0 1.0 7.8 0.4 6.6 4.2 12.5 0.0 1.9 20.2 1.5 0.9 0.0 7.9 6.9 0.0 15.5 0.2 33.7 14.0 18.7 36.3 2.9 16.8 2.7 9.1 1.3 24.4 6.9 5.6 1.7 15.4 0.0 0.0 0.0 0.3 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 43.9 44.9 14.4 37.2 29.5 24.1 24.9 37.0 13.8 11.0 DDAH2 G6A ENSG00000213722 "Dimethylarginine dimethylaminohydrolase 2" O95865 6 31727038-31730617 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 10.6;ASC TERT1: 13.2;EFO-21: 16.9;fHDF/TERT166: 10.5;SK-MEL-30: 10.6;U-2 OS: 12.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012509 Uncertain Supported "Centriolar satellite,Cytosol" 1800000 Cytosol "Centriolar satellite" "HPA012509: AB_1847533" "unprognostic (2.29e-2)" "unprognostic (1.38e-1)" "unprognostic (4.49e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.62e-1)" "unprognostic (8.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (9.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.24e-2)" "unprognostic (2.72e-2)" 24.3 7.8 12.5 11.1 10.3 5.5 22.7 3.1 7.8 32.1 17.0 7.9 12.9 2.6 34.6 22.0 18.4 18.1 26.7 20.7 11.8 10.8 16.9 12.9 37.4 16.5 10.6 6.6 22.5 4.3 3.0 6.2 13.7 13.1 19.8 5.4 13.0 18.1 13.2 6.8 15.1 22.3 27.1 18.9 21.4 11.4 7.3 9.9 14.1 35.4 17.1 8.9 16.3 23.4 2.9 5.5 8.0 2.7 2.3 0.5 0.3 0.4 6.6 0.2 1.4 10.6 13.2 0.7 0.6 0.3 0.4 0.1 4.3 0.7 0.2 16.9 10.5 0.8 0.0 6.2 0.0 0.1 8.9 0.5 0.5 0.1 0.3 0.9 0.0 8.5 0.1 0.8 0.1 0.1 0.2 2.2 0.0 3.6 0.5 2.5 0.1 0.2 0.3 0.5 0.0 7.5 0.7 0.4 0.9 0.3 0.0 10.6 0.7 0.9 1.1 0.8 12.6 0.2 0.1 2.7 9.2 2.5 7.3 1.5 0.2 8.0 0.8 7.7 0.5 2.6 0.3 2.9 0.2 0.3 1.5 2.5 0.1 0.1 1.3 2.3 2.7 5.5 0.4 0.3 12.5 10.3 3.1 7.8 11.8 10.8 10.6 6.6 13.1 9.9 DDX1 DBP-RB ENSG00000079785 "DEAD-box helicase 1" Q92499 2 15591178-15631111 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, mRNA processing, Transcription, Transcription regulation, tRNA processing" "Activator, DNA-binding, Exonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012280, HPA034502, HPA034503" Enhanced Enhanced Nucleoplasm,Cytosol 46000 Nucleoplasm Cytosol "CAB012280: , HPA034502: AB_10794321, HPA034503: AB_10795025" "unprognostic (9.94e-2)" "unprognostic (2.95e-2)" "unprognostic (3.07e-2)" "unprognostic (8.36e-3)" "unprognostic (9.28e-3)" "unprognostic (1.56e-2)" "prognostic unfavourable (9.09e-9)" "unprognostic (2.55e-1)" "unprognostic (2.05e-1)" "unprognostic (4.81e-3)" "unprognostic (3.89e-2)" "unprognostic (2.03e-1)" "prognostic favourable (9.69e-4)" "unprognostic (3.80e-1)" "unprognostic (1.34e-1)" "unprognostic (4.94e-2)" "unprognostic (1.20e-3)" 23.8 28.2 29.3 17.6 35.0 17.1 30.1 35.3 37.2 25.1 24.5 15.0 20.5 21.0 24.3 25.6 27.7 21.0 15.8 47.6 34.7 25.3 35.8 35.2 17.8 16.0 24.5 36.9 23.6 27.6 42.1 41.2 28.1 35.1 22.2 28.1 14.8 23.9 24.5 67.5 24.5 25.9 31.0 21.0 17.1 24.1 19.2 23.0 23.0 29.6 24.8 21.5 26.1 19.8 18.7 22.8 19.2 25.1 23.0 26.6 19.9 19.1 29.4 41.8 31.2 36.3 31.9 48.2 40.3 33.8 39.7 33.4 46.9 19.8 49.7 19.6 46.4 29.2 57.1 38.6 42.0 21.1 37.1 54.5 39.3 59.1 27.3 44.5 25.7 24.7 26.7 33.0 31.8 35.7 55.5 16.4 39.1 26.8 24.3 33.6 53.8 24.8 29.4 63.3 36.0 45.4 38.6 33.7 42.2 27.5 29.0 36.6 20.2 18.9 28.8 33.3 34.5 20.9 45.4 21.5 37.3 67.1 30.0 35.7 31.0 19.2 20.0 11.5 20.2 25.1 21.3 18.7 23.4 23.4 22.8 18.0 26.6 23.6 3.1 23.0 23.2 19.5 21.6 19.9 29.3 35.0 35.3 37.2 34.7 25.3 24.5 36.9 35.1 23.0 DDX10 "Dbp4, HRH-J8" ENSG00000178105 "DEAD-box helicase 10" Q13206 11 108665025-108940930 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004691 Approved Approved Nucleoli Nucleoli "HPA004691: AB_1078629" "unprognostic (9.49e-2)" "unprognostic (9.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (7.97e-2)" "unprognostic (1.48e-2)" "prognostic unfavourable (2.52e-5)" "unprognostic (2.86e-2)" "unprognostic (1.23e-2)" "unprognostic (1.06e-1)" "prognostic unfavourable (5.75e-4)" "unprognostic (1.00e-1)" "prognostic favourable (2.14e-5)" "unprognostic (5.20e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-1)" "unprognostic (2.43e-3)" 14.0 11.9 17.3 15.0 20.3 10.4 15.5 20.5 18.3 14.3 12.2 8.1 11.7 8.8 18.4 12.8 12.6 16.8 8.8 12.1 13.5 11.5 19.6 12.5 10.6 13.1 12.2 16.3 18.6 18.0 16.7 22.2 12.9 13.1 12.4 13.3 7.9 10.6 14.7 13.6 14.8 9.1 16.8 13.3 15.0 11.3 25.1 12.6 13.8 13.4 8.8 14.2 14.3 18.8 11.6 8.4 1.4 6.7 9.4 11.3 4.3 7.2 7.1 6.8 9.5 6.7 5.5 7.1 7.8 4.2 9.5 9.4 20.3 10.7 24.7 14.8 6.0 8.2 19.4 9.5 13.7 9.4 8.7 16.8 4.2 7.6 12.0 17.1 8.0 4.9 7.5 10.8 13.5 8.6 23.5 2.7 9.3 4.7 14.3 14.4 8.8 10.9 12.2 11.1 23.1 5.8 6.3 12.6 6.7 11.0 9.7 4.1 11.7 6.0 9.1 10.0 10.2 9.5 10.6 4.2 7.3 57.2 3.4 20.6 10.1 1.4 5.0 1.0 8.6 6.7 11.3 10.4 7.5 10.1 8.4 11.6 8.1 7.8 0.7 9.4 6.4 8.2 6.3 4.3 17.3 20.3 20.5 18.3 13.5 11.5 12.2 16.3 13.1 12.6 DDX11 "CHL1, CHLR1, KRG2, WABS" ENSG00000013573 "DEAD/H-box helicase 11" Q96FC9 12 31073845-31104791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA065197 Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Centrosome" Nucleoplasm "Nucleoli fibrillar center, Centrosome" "HPA065197: " "unprognostic (6.10e-2)" "unprognostic (1.48e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.79e-3)" "prognostic unfavourable (2.40e-4)" "unprognostic (4.87e-2)" "unprognostic (3.89e-3)" "unprognostic (3.53e-1)" "unprognostic (5.66e-2)" "unprognostic (1.25e-1)" "prognostic unfavourable (5.23e-8)" "unprognostic (1.89e-2)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (8.03e-3)" 6.3 5.3 6.4 8.0 8.7 21.0 5.9 18.1 10.5 7.6 6.1 6.0 8.8 7.1 11.0 3.7 7.6 7.5 5.1 4.0 7.0 2.7 6.5 7.0 4.9 14.9 8.4 4.6 9.6 19.0 7.7 9.3 5.6 7.1 8.0 8.6 5.0 11.3 7.1 8.8 14.2 12.1 8.0 6.7 10.9 8.0 8.2 9.4 33.2 7.2 6.4 11.1 5.8 7.8 5.8 4.9 1.3 7.3 4.3 5.5 1.9 12.4 12.2 14.1 12.6 2.2 4.7 20.8 7.7 3.9 9.1 9.7 14.4 21.2 16.3 10.8 4.1 12.3 11.1 10.6 7.3 14.9 22.8 19.4 20.2 8.9 0.8 13.6 12.6 4.5 4.7 11.5 9.0 4.4 9.5 36.5 6.5 10.3 23.3 20.4 29.7 6.5 18.8 22.1 22.7 4.8 14.2 10.2 7.5 7.9 12.2 3.9 10.3 8.7 3.6 7.9 15.6 15.3 14.0 14.8 11.4 39.0 9.4 10.9 7.2 0.0 2.3 1.3 4.2 2.5 3.3 5.2 4.0 3.1 3.1 5.8 4.1 5.5 1.1 4.3 7.3 4.9 3.4 1.9 6.4 8.7 18.1 10.5 7.0 2.7 8.4 4.6 7.1 9.4 DDX17 P72 ENSG00000100201 "DEAD-box helicase 17" Q92841 22 38483440-38507660 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, mRNA processing, mRNA splicing, RNA-mediated gene silencing, rRNA processing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024908, HPA063142" Supported Supported "Nuclear speckles" "Intracellular and membrane" 90000 "Nuclear speckles" "CAB024908: , HPA063142: " "unprognostic (1.46e-2)" "unprognostic (5.99e-3)" "unprognostic (4.24e-3)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-2)" "unprognostic (1.36e-2)" "prognostic favourable (6.06e-4)" "unprognostic (1.17e-1)" "unprognostic (5.51e-1)" "unprognostic (2.52e-2)" "unprognostic (2.73e-2)" "unprognostic (1.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" 49.7 43.1 46.3 49.2 54.5 19.8 50.8 69.7 52.0 47.7 53.3 56.5 54.4 33.1 58.5 82.9 37.5 52.2 46.1 39.9 47.0 31.2 34.3 41.9 41.5 52.6 64.0 37.7 67.8 41.5 68.5 83.7 49.4 46.0 46.2 36.8 51.4 43.9 51.8 89.2 60.3 38.7 52.7 47.1 54.1 39.7 24.6 63.1 69.3 59.8 29.2 47.7 54.5 52.9 10.3 12.4 23.7 9.5 4.0 9.9 6.1 29.6 28.8 58.8 35.3 39.0 44.9 30.7 25.3 25.3 37.0 36.0 27.5 24.8 57.6 17.5 33.1 32.8 64.3 35.9 41.4 56.7 36.7 35.8 48.2 32.9 41.8 45.7 42.6 31.3 47.1 24.1 41.7 42.2 36.9 65.2 29.3 19.3 32.1 38.9 37.8 14.0 58.3 32.8 35.3 35.1 39.7 34.0 20.0 39.7 31.4 41.9 27.1 35.3 34.2 31.6 19.7 20.1 19.0 50.4 34.8 49.6 40.8 29.6 38.8 8.5 9.5 11.0 9.9 7.3 9.4 9.0 8.0 7.1 6.8 10.3 5.8 7.5 23.7 4.0 6.8 12.4 7.9 6.1 46.3 54.5 69.7 52.0 47.0 31.2 64.0 37.7 46.0 63.1 DDX18 "Has1, MrDb" ENSG00000088205 "DEAD-box helicase 18" Q9NVP1 2 117814650-117832379 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035400, HPA041056" Approved Supported Nucleoli Nucleoli "HPA035400: AB_10672091, HPA041056: " "unprognostic (1.44e-1)" "unprognostic (2.22e-2)" "unprognostic (5.63e-2)" "prognostic unfavourable (2.64e-4)" "unprognostic (2.06e-1)" "unprognostic (1.77e-3)" "prognostic unfavourable (3.07e-4)" "unprognostic (8.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (1.42e-2)" "unprognostic (4.94e-2)" "unprognostic (8.51e-2)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (7.28e-2)" "unprognostic (5.65e-2)" 35.3 21.3 20.5 28.7 26.0 17.4 31.2 27.1 25.6 31.2 27.9 16.7 21.6 20.9 32.0 22.9 27.8 28.5 21.3 22.9 19.6 19.1 32.0 40.3 24.1 35.0 25.5 22.9 36.3 29.5 21.0 25.9 25.0 25.0 25.0 30.3 11.5 24.2 26.6 37.0 24.9 26.3 28.3 30.8 46.5 26.2 22.9 31.1 40.7 31.3 23.9 37.6 37.6 23.7 22.2 20.5 9.4 18.5 17.2 23.6 16.3 21.5 9.8 14.7 13.2 8.7 7.9 24.2 12.8 10.1 17.7 15.7 24.1 14.3 31.8 21.0 10.6 16.8 28.5 16.6 26.2 16.2 19.9 30.4 9.2 24.2 12.2 40.5 15.9 8.2 15.3 22.5 22.8 10.6 33.1 13.8 13.5 13.4 22.1 21.2 36.8 14.8 19.3 22.9 27.9 11.7 12.8 14.1 24.0 14.9 16.4 16.6 10.4 22.4 8.1 15.9 23.4 11.1 23.0 15.9 19.8 88.2 11.7 19.2 7.1 6.2 13.8 9.4 16.2 17.3 20.6 22.2 19.3 18.5 12.5 19.1 23.6 20.7 3.6 17.2 18.5 20.5 15.0 16.3 20.5 26.0 27.1 25.6 19.6 19.1 25.5 22.9 25.0 31.1 DDX19A "DDX19L, FLJ11126" ENSG00000168872 "DEAD-box helicase 19A" Q9NUU7 16 70346829-70373383 "Enzymes, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045252, HPA066668" Approved Uncertain Nucleoplasm Nucleoplasm "HPA045252: AB_10961128, HPA066668: " "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (9.07e-2)" "unprognostic (3.95e-2)" "unprognostic (2.18e-2)" "prognostic unfavourable (2.38e-4)" "prognostic unfavourable (8.05e-5)" "unprognostic (1.45e-1)" "unprognostic (1.59e-1)" "unprognostic (1.67e-1)" "unprognostic (1.30e-1)" "unprognostic (5.87e-2)" "unprognostic (1.24e-1)" "unprognostic (2.01e-2)" "unprognostic (1.49e-1)" "unprognostic (3.01e-2)" "unprognostic (6.68e-3)" 18.4 20.6 14.5 15.5 19.7 9.8 18.1 16.6 19.6 16.9 19.2 19.2 17.8 9.3 22.0 14.2 19.2 17.1 16.1 22.1 18.6 13.5 16.6 24.8 14.4 18.0 17.1 15.5 21.6 22.5 31.7 17.4 21.8 15.1 15.4 14.4 14.2 14.4 21.1 51.5 15.8 13.5 25.9 15.4 14.1 17.2 9.7 13.7 17.1 19.7 14.4 18.4 19.5 15.5 8.1 14.2 7.9 11.4 8.2 10.3 8.8 12.9 14.7 15.5 15.7 23.3 15.9 14.8 16.5 17.1 26.3 20.4 22.0 9.7 21.8 15.7 17.5 14.9 27.8 16.5 21.8 7.3 15.1 11.4 12.0 27.0 21.1 19.8 9.5 19.5 11.9 23.9 18.8 16.7 27.4 5.7 15.7 18.6 22.0 16.4 25.0 9.0 27.3 10.4 29.8 15.8 8.0 12.8 17.2 42.4 9.3 12.4 17.0 12.6 11.3 18.3 14.5 11.5 15.7 16.1 24.1 47.9 12.3 18.1 17.9 7.9 11.4 5.8 10.2 10.7 9.4 7.7 8.9 10.0 14.2 8.1 9.9 10.3 0.7 8.2 9.6 7.3 7.5 8.8 14.5 19.7 16.6 19.6 18.6 13.5 17.1 15.5 15.1 13.7 DDX19B "DBP5, DDX19" ENSG00000157349 "DEAD-box helicase 19B" Q9UMR2 16 70289663-70335283 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037229, CAB037284, HPA046380, HPA066668" Approved Uncertain Nucleoplasm Nucleoplasm "CAB037229: AB_1840791, CAB037284: AB_1840792, HPA046380: , HPA066668: " "unprognostic (2.91e-2)" "unprognostic (5.37e-2)" "unprognostic (6.48e-2)" "unprognostic (3.55e-2)" "unprognostic (3.98e-2)" "unprognostic (4.05e-2)" "unprognostic (2.93e-2)" "unprognostic (1.98e-2)" "unprognostic (1.40e-1)" "unprognostic (1.05e-1)" "unprognostic (6.33e-2)" "unprognostic (4.07e-1)" "unprognostic (7.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.50e-1)" "unprognostic (1.04e-1)" "unprognostic (6.32e-2)" 22.2 18.6 8.8 16.6 12.7 19.4 20.1 30.4 16.3 13.1 16.7 14.6 13.8 14.4 15.0 13.9 16.0 13.2 15.2 15.0 8.3 8.3 15.9 33.9 16.6 15.3 10.5 10.7 14.6 21.6 20.3 17.9 12.0 13.2 13.8 18.2 19.3 16.8 15.2 24.8 26.9 16.6 15.7 10.1 17.8 18.5 64.3 12.3 17.4 18.0 16.9 20.8 16.2 13.9 21.1 21.1 27.0 28.6 22.1 35.4 22.5 2.0 12.3 17.5 15.9 9.7 12.9 15.2 9.9 14.1 21.8 22.8 26.1 15.1 16.1 9.4 12.4 12.1 0.1 5.7 22.6 6.6 11.1 9.5 8.0 21.4 20.8 20.3 9.2 15.9 11.2 16.5 12.6 16.7 9.6 7.0 13.3 14.1 0.0 29.3 10.9 5.1 28.1 9.5 23.2 13.0 11.4 11.5 15.1 23.4 5.3 12.6 11.9 18.1 10.1 10.3 9.2 8.5 9.1 15.0 7.8 37.3 3.4 16.6 13.2 27.0 22.1 19.0 23.2 28.6 22.3 21.1 20.9 25.3 21.1 19.0 19.0 18.0 4.1 22.1 17.7 6.5 35.4 22.5 8.8 12.7 30.4 16.3 8.3 8.3 10.5 10.7 13.2 12.3 DDX20 "DP103, GEMIN3" ENSG00000064703 "DEAD-box helicase 20" Q9UHI6 1 111755245-111768016 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 81.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005516, CAB015427" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Intracellular and membrane" "Nucleoplasm, Nuclear bodies" Cytosol "CAB015427: AB_629518, HPA005516: AB_1849612" "unprognostic (3.71e-2)" "unprognostic (5.25e-2)" "prognostic favourable (9.85e-5)" "unprognostic (8.73e-2)" "unprognostic (2.51e-2)" "unprognostic (7.09e-2)" "prognostic unfavourable (6.35e-6)" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (7.46e-3)" "unprognostic (4.21e-1)" "unprognostic (5.22e-2)" "unprognostic (1.05e-3)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (4.23e-1)" "unprognostic (1.30e-2)" 3.1 2.8 2.9 2.7 4.3 5.9 9.8 5.8 5.1 2.7 2.6 1.8 2.6 2.0 4.0 2.9 2.6 3.7 1.7 2.0 4.3 1.6 2.7 2.4 4.1 3.8 2.4 1.9 3.9 2.9 4.0 3.9 2.7 3.4 2.9 2.6 1.2 2.6 2.7 5.1 2.5 3.5 2.9 5.6 4.5 2.8 81.7 3.3 5.1 3.2 1.7 4.1 2.9 5.0 11.9 7.4 12.7 7.4 10.5 14.1 7.8 11.4 4.7 12.2 11.0 8.8 7.0 11.4 11.2 8.7 16.1 15.7 7.0 4.0 26.8 8.8 7.6 9.2 14.4 11.3 18.0 12.2 13.0 13.0 9.2 7.2 8.8 12.8 9.6 7.0 9.9 13.7 13.9 11.1 12.4 9.8 12.2 10.8 15.7 13.0 15.3 9.6 15.4 20.1 6.7 10.5 9.0 12.7 11.5 10.8 13.5 18.0 8.4 13.6 9.8 9.8 14.5 17.5 13.0 4.9 6.9 20.5 10.2 13.2 22.1 12.7 7.0 6.9 10.0 7.3 13.3 11.9 11.7 11.8 7.4 10.1 14.1 12.3 5.0 10.5 7.4 5.2 11.7 7.8 2.9 4.3 5.8 5.1 4.3 1.6 2.4 1.9 3.4 3.3 DDX21 "GURDB, RH-II/GU" ENSG00000165732 "DExD-box helicase 21" Q9NR30 10 68956128-68985073 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing, Transcription" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036592, HPA036593" Enhanced Enhanced Nucleoplasm,Nucleoli 14000 Nucleoli Nucleoplasm "HPA036592: AB_10673625, HPA036593: AB_2675208" "unprognostic (3.04e-1)" "unprognostic (6.81e-3)" "unprognostic (1.13e-2)" "unprognostic (1.21e-2)" "unprognostic (1.75e-2)" "unprognostic (6.71e-3)" "unprognostic (1.34e-2)" "unprognostic (1.99e-2)" "unprognostic (1.29e-1)" "unprognostic (1.92e-1)" "prognostic unfavourable (3.12e-4)" "unprognostic (1.64e-1)" "unprognostic (1.39e-2)" "unprognostic (9.33e-2)" "unprognostic (5.41e-2)" "unprognostic (1.24e-2)" "unprognostic (5.74e-3)" 37.5 16.0 10.0 26.6 13.3 46.8 24.4 8.0 11.8 18.5 20.1 7.2 16.2 13.3 18.7 13.7 28.3 20.1 17.6 19.1 11.4 8.0 25.1 48.0 25.9 24.4 14.9 7.2 30.2 27.9 15.6 20.7 22.8 18.3 14.0 17.6 5.9 18.0 17.8 61.2 22.5 18.5 19.0 20.4 43.5 19.0 12.9 13.3 27.1 18.1 24.1 25.8 33.2 22.4 12.6 11.5 17.1 17.3 7.7 15.0 6.2 32.8 19.5 11.4 35.2 10.3 13.6 24.1 22.6 18.3 29.2 24.9 63.1 22.5 49.6 13.9 18.7 29.3 43.9 28.2 39.2 15.4 30.9 34.7 13.9 26.2 22.1 82.5 33.0 14.0 36.7 34.9 58.4 21.2 66.0 24.8 20.5 15.0 32.3 18.0 31.2 41.7 28.9 18.7 24.3 19.4 17.7 23.6 25.3 20.3 45.1 26.3 25.5 17.3 21.8 17.2 24.3 23.0 39.6 28.6 37.8 73.2 14.3 62.6 11.6 5.0 9.7 17.1 8.4 15.0 15.0 12.6 10.9 11.0 11.5 10.4 10.3 11.3 4.5 7.7 17.3 10.8 7.9 6.2 10.0 13.3 8.0 11.8 11.4 8.0 14.9 7.2 18.3 13.3 DDX23 "prp28, PRPF28, SNRNP100, U5-100K" ENSG00000174243 "DEAD-box helicase 23" Q9BUQ8 12 48829764-48852842 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038680, HPA039037" Approved Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA038680: AB_10795401, HPA039037: " "unprognostic (1.32e-3)" "unprognostic (8.90e-2)" "unprognostic (8.92e-2)" "unprognostic (7.12e-2)" "unprognostic (5.34e-2)" "unprognostic (1.47e-1)" "prognostic unfavourable (3.03e-5)" "unprognostic (3.54e-2)" "unprognostic (5.68e-2)" "unprognostic (2.19e-2)" "unprognostic (1.69e-1)" "unprognostic (8.34e-2)" "unprognostic (5.94e-2)" "unprognostic (9.78e-2)" "unprognostic (6.88e-2)" "unprognostic (2.59e-2)" "unprognostic (1.44e-1)" 26.1 26.5 29.5 35.6 34.2 19.4 27.2 32.8 35.6 26.7 32.8 23.3 27.5 27.9 31.0 22.3 31.0 31.1 25.2 25.1 29.8 20.3 25.2 37.7 27.7 35.2 26.5 25.3 36.2 30.4 32.2 28.1 34.4 25.0 29.9 32.6 24.7 31.1 27.0 44.4 30.6 32.3 29.4 24.1 40.0 30.6 24.9 32.0 46.8 28.2 29.8 38.9 28.9 47.9 12.0 11.5 19.6 13.3 11.2 19.8 10.6 21.6 49.4 23.5 24.9 23.5 16.3 25.0 26.8 20.6 30.5 19.4 48.1 28.9 27.3 29.5 22.2 19.6 50.9 24.4 26.1 42.8 27.0 36.2 42.1 21.7 12.7 36.5 33.0 15.7 22.0 32.3 19.4 24.9 47.9 24.5 22.1 30.0 34.6 34.7 34.9 23.5 37.0 27.8 21.7 18.0 30.5 29.0 16.9 26.9 30.8 11.2 30.1 33.6 22.3 23.1 16.9 11.3 21.2 18.5 25.8 33.0 19.6 25.8 12.6 17.1 11.1 19.6 19.5 13.3 19.8 12.0 14.5 17.6 10.8 11.4 14.0 16.9 11.9 11.2 8.9 11.5 13.1 10.6 29.5 34.2 32.8 35.6 29.8 20.3 26.5 25.3 25.0 32.0 DDX24 ENSG00000089737 "DEAD-box helicase 24" Q9GZR7 14 94048291-94081245 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 103.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002554 Uncertain Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA002554: AB_1078631" "unprognostic (7.48e-2)" "unprognostic (3.02e-2)" "unprognostic (8.95e-2)" "unprognostic (2.12e-1)" "unprognostic (2.31e-1)" "unprognostic (4.06e-3)" "unprognostic (8.81e-2)" "unprognostic (2.66e-3)" "unprognostic (2.77e-1)" "unprognostic (2.28e-2)" "unprognostic (1.60e-3)" "unprognostic (4.13e-2)" "prognostic favourable (3.06e-9)" "prognostic unfavourable (2.89e-4)" "unprognostic (6.15e-2)" "unprognostic (1.23e-1)" "unprognostic (5.66e-2)" 18.0 45.5 19.7 13.7 41.3 53.3 18.5 31.4 40.8 17.4 20.9 21.9 14.3 13.6 23.2 103.0 20.1 18.9 21.3 28.6 25.0 31.3 36.3 30.1 16.4 27.4 22.0 29.0 21.4 12.5 8.3 32.0 11.2 38.7 16.0 14.6 17.4 15.9 17.7 28.5 23.4 12.6 17.9 21.8 18.1 15.0 38.5 17.4 14.3 25.3 11.8 25.8 21.7 14.9 4.1 3.1 10.6 3.3 6.2 5.3 5.0 3.8 1.0 7.1 4.6 4.3 5.6 1.7 10.7 8.9 13.9 12.5 1.3 2.4 17.7 4.0 2.3 2.5 7.3 0.6 15.2 7.7 0.4 9.4 2.0 5.7 3.5 13.5 4.2 0.9 4.0 2.5 2.4 2.3 4.9 5.2 5.9 10.6 4.0 11.5 4.7 0.1 5.4 16.5 2.0 10.1 1.4 5.6 5.2 10.5 2.6 4.9 4.1 4.8 6.8 4.0 2.6 5.1 3.2 2.1 13.6 19.0 5.7 7.4 3.1 10.6 3.3 2.5 5.0 2.6 1.4 2.9 2.9 3.0 2.0 4.1 5.3 5.3 2.6 6.2 2.5 3.1 3.3 5.0 19.7 41.3 31.4 40.8 25.0 31.3 22.0 29.0 38.7 17.4 DDX25 GRTH ENSG00000109832 "DEAD-box helicase 25" Q9UHL0 11 125903348-125943702 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Translation regulation, Transport" "Developmental protein, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 17.3;testis: 64.2" "Group enriched" "Detected in some" 4 "NTERA-2: 13.6;SCLC-21H: 11.0" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020137 Enhanced "HPA020137: AB_1847552" "unprognostic (5.78e-3)" "unprognostic (9.75e-3)" "unprognostic (7.93e-2)" "unprognostic (5.09e-3)" "unprognostic (1.11e-2)" "unprognostic (1.78e-2)" "unprognostic (1.54e-1)" "unprognostic (2.91e-3)" "unprognostic (6.24e-5)" "unprognostic (2.57e-1)" "unprognostic (2.44e-3)" "unprognostic (3.89e-1)" "unprognostic (3.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.69e-1)" 0.7 2.8 8.7 0.8 13.2 0.9 0.8 7.9 17.3 0.8 0.8 2.0 0.0 1.0 0.9 0.9 0.8 0.9 0.8 0.7 8.4 7.1 2.7 0.8 0.8 0.8 4.8 8.9 1.2 1.8 2.6 7.1 0.9 5.9 0.9 0.8 2.3 0.8 1.0 0.8 1.6 0.8 0.7 3.4 0.9 1.0 64.2 3.0 0.0 4.3 0.0 0.8 0.7 0.2 0.6 0.5 3.3 0.3 1.3 0.5 0.1 0.0 0.0 2.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.9 0.0 0.2 1.5 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.6 2.0 0.1 13.6 0.0 0.5 0.0 0.0 0.0 0.1 11.0 2.5 0.2 0.0 1.9 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.8 2.1 0.3 0.6 0.3 0.2 0.2 0.4 0.5 0.2 0.1 0.6 0.4 0.3 3.3 1.3 0.2 0.5 0.1 0.1 8.7 13.2 7.9 12.5 8.4 7.1 4.8 8.9 5.9 3.0 DDX27 "dJ686N3.1, DRS1" ENSG00000124228 "DEAD-box helicase 27" Q96GQ7 20 49219295-49244077 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047087 Uncertain Approved Nucleoli Nucleoli "HPA047087: AB_10964059" "unprognostic (4.47e-2)" "unprognostic (2.41e-2)" "unprognostic (3.13e-1)" "prognostic unfavourable (1.44e-5)" "unprognostic (2.82e-1)" "unprognostic (7.12e-2)" "prognostic unfavourable (6.70e-7)" "unprognostic (2.28e-1)" "unprognostic (9.53e-2)" "unprognostic (2.74e-1)" "unprognostic (7.18e-2)" "unprognostic (5.84e-3)" "prognostic unfavourable (1.73e-4)" "unprognostic (1.26e-1)" "unprognostic (4.32e-1)" "unprognostic (1.99e-2)" "unprognostic (1.27e-1)" 22.0 22.5 21.9 33.0 23.2 40.9 23.6 34.8 26.3 24.3 26.4 16.3 20.4 23.2 26.2 19.1 26.5 23.9 27.1 19.2 22.6 17.3 25.9 21.0 20.1 32.3 19.9 18.8 37.4 27.3 25.9 25.6 23.9 21.2 22.0 22.1 14.4 22.9 24.3 32.9 27.8 33.6 20.0 20.7 34.1 22.9 25.0 24.0 30.6 23.5 19.4 35.3 24.0 27.2 30.4 28.0 22.2 24.2 18.2 26.7 18.6 20.1 19.1 9.8 7.5 11.0 10.1 28.0 13.4 11.0 42.3 19.6 62.3 22.6 24.0 25.0 10.9 28.6 21.8 21.5 31.5 8.4 12.8 18.2 16.1 30.2 16.1 23.0 21.3 10.7 25.2 24.6 19.0 7.0 24.7 13.3 13.7 13.5 24.2 30.4 18.6 24.9 20.9 24.5 22.0 15.3 15.6 12.8 15.2 37.4 54.0 22.5 28.5 26.7 8.7 27.2 24.0 22.7 27.8 15.2 16.3 31.4 17.4 18.3 17.5 11.1 19.8 22.2 21.7 21.2 22.8 29.4 20.6 19.7 23.3 30.4 26.7 20.3 8.1 18.2 24.2 28.0 26.3 18.6 21.9 23.2 34.8 26.3 22.6 17.3 19.9 18.8 21.2 24.0 DDX28 "FLJ11282, MDDX28" ENSG00000182810 "DEAD-box helicase 28" Q9NUL7 16 68021274-68023442 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041911, HPA053585" Approved Supported Nucleoli,Mitochondria,Cytosol "Mitochondria, Cytosol" Nucleoli "HPA041911: AB_10794161, HPA053585: " "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (6.10e-3)" "unprognostic (8.03e-2)" "unprognostic (1.58e-1)" "unprognostic (8.69e-2)" "unprognostic (8.46e-2)" "unprognostic (9.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.63e-2)" "unprognostic (8.14e-3)" "unprognostic (8.53e-2)" "prognostic favourable (2.07e-10)" "unprognostic (1.58e-2)" "unprognostic (6.21e-2)" "unprognostic (2.23e-1)" "unprognostic (2.47e-1)" 9.8 12.7 6.2 6.7 8.3 19.7 7.1 6.0 12.9 8.3 7.2 6.4 6.8 5.2 7.5 7.3 9.7 7.1 7.0 9.2 5.2 5.9 8.9 12.4 5.8 18.4 6.4 5.1 8.6 13.3 6.8 4.6 17.1 6.6 6.1 6.0 7.8 6.3 5.2 16.2 9.9 7.9 5.3 3.0 11.1 7.0 11.5 2.7 14.6 10.2 7.3 10.6 8.0 4.8 17.8 18.0 22.9 19.1 17.0 22.9 16.6 6.1 9.1 4.5 5.4 6.3 3.5 10.5 4.2 6.2 10.6 7.6 8.8 9.8 23.0 6.5 5.2 11.1 6.4 10.2 6.3 3.1 10.5 8.3 4.8 9.1 8.5 13.0 9.0 6.8 11.1 8.7 8.0 5.9 14.8 3.6 4.7 13.7 13.6 18.3 11.0 6.8 13.4 4.2 24.6 7.4 7.1 9.4 6.3 17.1 4.9 9.3 9.4 14.3 4.2 4.7 4.0 6.7 6.9 8.1 9.8 22.1 5.8 10.1 6.3 17.7 19.1 22.9 15.7 18.8 17.3 12.6 14.6 16.9 18.0 17.8 22.9 16.9 6.3 17.0 18.5 9.0 13.8 16.6 6.2 8.3 6.0 12.9 5.2 5.9 6.4 5.1 6.6 2.7 DDX31 "FLJ13633, FLJ14578, FLJ23349, PPP1R25" ENSG00000125485 "DEAD-box helicase 31" Q9H8H2 9 132592997-132670401 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020891 Supported "Nucleoli,Golgi apparatus,Vesicles" Nucleoli "Golgi apparatus, Vesicles" "HPA020891: " "unprognostic (5.71e-2)" "unprognostic (1.76e-2)" "unprognostic (2.56e-1)" "unprognostic (7.91e-2)" "unprognostic (5.79e-2)" "unprognostic (9.94e-2)" "prognostic unfavourable (1.68e-7)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.66e-1)" "unprognostic (3.90e-2)" "unprognostic (9.57e-3)" "unprognostic (4.57e-3)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" 6.8 6.9 8.2 15.3 11.2 6.0 12.3 18.4 8.5 7.5 6.6 9.4 12.6 5.0 8.9 8.8 9.8 8.8 7.5 5.4 6.3 6.3 8.4 9.2 12.0 15.1 9.1 5.7 16.9 17.3 10.0 8.8 5.8 9.8 9.2 8.0 7.4 12.7 12.6 12.9 14.0 7.2 12.7 12.9 8.7 6.8 15.2 8.3 6.8 22.7 10.8 13.8 7.2 12.6 5.0 4.5 1.9 2.7 3.1 6.9 3.0 7.1 13.2 6.5 8.9 7.9 7.2 12.7 7.6 7.5 12.1 9.2 14.7 14.7 17.8 7.0 7.1 20.0 20.3 8.9 9.7 10.9 7.5 9.6 11.8 7.7 9.6 17.1 7.9 6.3 12.2 12.3 17.4 7.9 17.7 7.0 10.0 15.3 11.9 9.3 16.0 13.6 12.6 11.5 20.5 11.0 6.8 11.7 8.3 14.0 12.4 10.6 26.0 5.0 6.6 20.5 9.3 11.6 11.8 3.4 10.7 13.9 7.4 10.9 15.4 0.0 1.9 1.9 5.7 2.7 4.7 4.2 5.5 4.4 4.5 5.0 6.9 5.1 0.3 3.1 1.9 2.8 3.6 3.0 8.2 11.2 18.4 8.5 6.3 6.3 9.1 5.7 9.8 8.3 DDX39A "BAT1L, DDX39, DDXL, URH49" ENSG00000123136 "DExD-box helicase 39A" O00148 19 14408819-14419383 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 60.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055334 Approved Approved "Nuclear speckles" "Nuclear speckles" "HPA055334: " "unprognostic (1.31e-1)" "prognostic favourable (6.86e-4)" "unprognostic (2.41e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (5.20e-2)" "unprognostic (2.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.87e-1)" "unprognostic (8.81e-2)" "unprognostic (1.64e-1)" "unprognostic (3.09e-2)" "prognostic unfavourable (1.50e-10)" "unprognostic (1.55e-3)" "unprognostic (8.57e-2)" "unprognostic (3.92e-1)" "unprognostic (7.38e-3)" 10.9 8.5 7.2 20.6 11.4 41.4 10.5 9.1 7.9 8.2 10.9 11.0 4.4 13.0 9.4 7.2 15.9 7.0 8.1 7.8 6.6 6.1 9.7 12.1 10.3 31.2 12.6 5.0 7.4 8.8 3.0 7.4 10.5 10.0 7.3 8.9 5.2 7.9 4.4 7.9 10.6 12.8 6.8 9.4 23.4 10.4 60.7 10.3 39.9 8.4 16.3 26.1 10.3 8.8 36.7 36.6 7.7 28.5 21.5 39.7 33.6 32.6 26.8 13.8 26.6 5.7 4.1 13.5 14.5 8.1 30.3 18.7 27.2 17.7 63.2 15.5 12.0 20.2 33.9 23.6 12.4 22.0 17.7 67.8 31.3 19.5 10.0 36.8 30.3 5.7 5.3 19.7 8.0 15.8 41.6 27.8 16.8 39.5 63.1 54.7 26.3 41.1 43.8 24.4 36.9 10.8 26.9 32.1 17.7 10.8 22.6 16.3 24.9 36.0 14.8 26.8 16.7 44.1 32.5 28.9 50.7 65.0 30.1 40.3 26.8 6.8 25.9 7.7 35.6 28.5 30.5 36.7 28.4 28.2 36.6 33.2 24.9 26.7 7.7 21.5 23.4 22.6 39.7 33.6 7.2 11.4 9.1 7.9 6.6 6.1 12.6 5.0 10.0 10.3 DDX39B "BAT1, D6S81E, UAP56" ENSG00000198563 "DExD-box helicase 39B" Q13838 6 31530219-31542448 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Transport" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034012, HPA055334, HPA058450" Enhanced Enhanced "Nuclear speckles" 120000 "Nuclear speckles" "CAB034012: AB_2243237, HPA055334: , HPA058450: " "unprognostic (2.78e-2)" "unprognostic (1.30e-2)" "unprognostic (6.86e-3)" "unprognostic (3.44e-2)" "unprognostic (3.22e-2)" "unprognostic (5.13e-3)" "unprognostic (2.89e-2)" "unprognostic (1.19e-2)" "unprognostic (4.89e-3)" "unprognostic (1.25e-1)" "unprognostic (2.81e-2)" "unprognostic (3.53e-3)" "prognostic unfavourable (1.11e-6)" "unprognostic (2.85e-1)" "unprognostic (1.72e-1)" "unprognostic (1.90e-2)" "prognostic favourable (1.43e-5)" 27.1 31.0 16.1 33.3 20.6 11.3 29.1 37.3 22.7 34.9 35.4 31.8 25.6 8.2 53.4 75.4 40.2 43.5 23.8 28.3 16.3 12.8 25.3 28.6 29.1 26.5 19.2 15.6 49.8 36.8 17.6 50.6 25.9 19.7 35.3 19.3 35.3 26.4 34.4 39.0 24.7 33.2 25.8 30.8 39.9 27.7 21.3 17.8 45.5 31.2 30.5 37.1 32.9 27.7 5.1 8.5 3.8 6.2 3.4 7.4 5.5 3.0 16.1 13.3 6.5 13.5 11.6 7.7 3.4 3.9 10.0 9.0 4.0 4.0 3.1 11.7 16.7 5.6 15.1 25.6 9.4 2.7 40.3 5.5 4.7 9.6 4.5 7.4 6.0 17.9 15.4 10.1 31.7 6.3 23.8 2.5 8.3 2.1 6.5 27.0 5.6 2.8 5.5 5.9 3.6 20.2 3.9 6.1 17.0 6.8 3.1 3.9 2.3 6.4 3.5 1.3 4.8 1.2 8.9 10.2 12.6 25.0 0.8 10.4 5.3 3.5 6.1 3.8 5.4 6.2 6.7 4.5 6.8 6.5 8.5 5.1 7.4 6.8 3.4 3.4 5.6 6.5 7.3 5.5 16.1 20.6 37.3 22.7 16.3 12.8 19.2 15.6 19.7 17.8 DDX3X "DBX, DDX14, DDX3, HLP2" ENSG00000215301 "DEAD-box helicase 3, X-linked" O00571 X 41333284-41364472 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059585" Supported Supported Approved Nucleoplasm,Cytosol 110000 Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: " "unprognostic (2.42e-2)" "unprognostic (1.11e-1)" "unprognostic (8.01e-3)" "unprognostic (1.66e-1)" "unprognostic (8.12e-2)" "unprognostic (6.43e-2)" "unprognostic (1.17e-3)" "unprognostic (1.88e-1)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.25e-2)" "unprognostic (2.05e-1)" "unprognostic (1.51e-1)" "unprognostic (2.95e-1)" "unprognostic (4.77e-1)" "unprognostic (9.44e-2)" "unprognostic (2.93e-2)" 80.9 49.3 26.1 40.0 34.5 49.3 46.5 31.1 36.2 52.4 43.3 35.1 21.3 29.5 56.4 25.9 53.5 56.3 42.6 47.6 30.8 24.5 55.6 77.9 45.3 40.4 41.4 29.0 60.1 30.9 68.7 60.2 79.9 37.9 30.0 29.2 30.8 37.4 26.5 63.4 42.2 54.0 57.2 53.9 46.1 43.0 27.0 39.0 49.2 45.6 44.0 42.6 55.8 50.2 13.1 20.5 32.0 21.6 17.3 21.5 17.9 45.4 50.5 47.2 25.9 55.6 47.2 28.8 33.1 46.6 34.0 27.4 51.9 30.6 0.5 23.7 37.1 30.7 57.7 46.6 56.7 26.9 45.0 28.9 50.3 31.2 28.9 54.1 52.0 34.1 33.1 57.3 55.4 53.3 53.0 28.6 31.6 34.4 34.1 16.9 45.4 20.4 40.0 50.3 37.0 32.0 61.2 32.3 48.9 75.0 38.5 39.7 34.6 36.8 48.1 35.1 37.6 37.5 39.3 33.4 39.6 44.9 35.4 32.8 33.2 22.5 20.2 17.5 14.8 21.1 21.5 13.1 14.5 16.3 20.5 9.0 16.3 15.1 32.0 17.3 21.6 6.9 14.3 17.9 26.1 34.5 31.1 36.2 30.8 24.5 41.4 29.0 37.9 39.0 DDX3Y DBY ENSG00000067048 "DEAD-box helicase 3, Y-linked" O15523 Y 12904108-12920478 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 40.6;HEL: 41.4;U-266/84: 34.4;U-698: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059583" Enhanced Supported Supported Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059583: " "unprognostic (3.89e-2)" "unprognostic (1.70e-1)" "prognostic favourable (4.70e-5)" "unprognostic (6.50e-2)" "unprognostic (4.74e-2)" "unprognostic (2.22e-2)" "unprognostic (4.17e-2)" "unprognostic (3.37e-2)" "unprognostic (9.61e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-1)" "unprognostic (2.66e-2)" "unprognostic (7.87e-2)" 12.0 10.5 4.9 29.5 14.1 46.1 8.7 17.0 16.3 0.4 24.4 12.6 31.5 7.6 0.4 29.7 12.2 0.4 14.2 10.8 5.6 7.1 8.9 26.5 20.0 17.7 5.7 0.0 0.4 14.5 0.4 12.2 14.0 20.2 26.7 15.8 15.1 20.4 32.6 17.7 8.4 16.0 40.7 6.2 34.3 8.9 41.9 0.0 26.9 10.8 21.4 19.3 14.4 0.0 6.1 8.8 6.5 7.1 6.5 8.4 3.8 0.1 7.5 0.0 0.0 0.0 0.0 5.5 18.6 13.3 9.8 12.1 0.0 0.0 40.6 0.0 18.3 0.0 0.0 0.0 17.3 10.2 0.0 41.4 0.0 12.2 9.7 0.0 0.0 10.3 11.6 0.0 0.0 0.0 0.0 0.0 11.6 0.0 16.0 0.0 7.4 0.0 0.0 4.9 7.4 10.5 11.2 12.2 0.0 0.0 0.0 13.6 0.0 9.7 13.3 15.3 0.0 0.0 12.2 21.9 34.4 30.2 1.8 0.0 0.0 1.6 6.2 5.7 8.4 7.1 7.7 6.1 6.4 7.1 8.8 5.9 7.8 6.5 6.5 6.5 4.6 2.5 5.7 3.8 4.9 14.1 17.0 16.3 5.6 7.1 5.7 0.0 20.2 0.0 DDX4 VASA ENSG00000152670 "DEAD-box helicase 4" Q9NQI0 5 55738017-55817157 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 171 "testis: 60.4" "Cell line enhanced" "Detected in some" "BEWO: 5.9;HEK 293: 1.6;NB-4: 1.0;PC-3: 3.3" "Cancer enriched" "Detected in single" 37 "testis cancer: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026170, HPA037763, HPA037764" Enhanced "CAB026170: , HPA037763: , HPA037764: " "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (1.54e-1)" "unprognostic (2.58e-1)" "unprognostic (3.80e-2)" "unprognostic (3.03e-1)" "unprognostic (5.35e-2)" "unprognostic (3.91e-1)" "unprognostic (3.77e-2)" "unprognostic (3.28e-1)" "unprognostic (5.73e-2)" "unprognostic (5.43e-7)" "unprognostic (4.84e-2)" "unprognostic (1.12e-1)" "unprognostic (5.60e-2)" "unprognostic (1.55e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 60.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 3.3 0.0 0.1 0.0 0.7 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 DDX41 "ABS, MGC8828" ENSG00000183258 "DEAD-box helicase 41" Q9UJV9 5 177511577-177517469 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017911, HPA048803" Supported Supported Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA017911: AB_1847558, HPA048803: " "unprognostic (2.52e-1)" "unprognostic (1.51e-1)" "unprognostic (7.57e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-1)" "unprognostic (2.61e-2)" "unprognostic (4.21e-3)" "unprognostic (2.60e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (4.47e-2)" "prognostic unfavourable (2.21e-6)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (1.75e-1)" 17.9 22.7 27.0 25.1 30.7 17.2 16.5 22.8 39.2 19.1 21.2 16.9 18.5 25.5 19.5 16.5 23.0 22.1 17.1 15.3 29.3 20.1 23.7 29.3 16.8 19.9 22.1 24.8 21.2 18.0 22.2 15.1 22.1 27.4 16.3 15.4 19.0 19.0 17.5 36.6 21.7 26.8 16.7 14.8 21.9 19.7 16.8 15.4 24.9 22.9 18.2 23.5 19.6 18.4 15.9 22.5 16.4 22.8 18.6 20.6 18.0 21.0 24.1 13.2 15.5 13.6 16.1 44.5 18.9 11.5 13.9 10.3 39.2 19.7 23.6 28.8 17.8 17.3 17.2 43.3 9.5 56.4 21.6 30.0 24.5 23.2 18.0 31.0 31.9 15.8 15.3 13.2 17.8 17.7 26.0 16.9 16.4 45.4 25.8 15.2 23.2 19.5 28.1 16.0 27.8 15.5 24.5 15.7 17.2 20.1 26.8 22.6 18.7 45.3 18.9 25.5 15.1 16.2 29.4 20.3 23.8 40.3 27.9 34.2 16.7 10.6 22.8 16.4 16.1 21.5 20.6 15.9 16.0 15.3 22.5 14.1 14.8 15.5 7.7 18.6 21.4 10.2 15.6 18.0 27.0 30.7 22.8 39.2 29.3 20.1 22.1 24.8 27.4 15.4 DDX42 "RHELP, RNAHP, SF3b125, SF3B8" ENSG00000198231 "DEAD-box helicase 42" Q86XP3 17 63773603-63819317 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023447, HPA023571, HPA025941" Approved Enhanced "Nuclear speckles" "Nuclear speckles" "HPA023447: AB_1847560, HPA023571: AB_1847561, HPA025941: AB_1847562" "unprognostic (3.46e-1)" "unprognostic (7.11e-2)" "unprognostic (8.44e-2)" "unprognostic (1.29e-1)" "unprognostic (2.49e-2)" "unprognostic (3.17e-2)" "prognostic unfavourable (2.84e-4)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (1.90e-1)" "unprognostic (2.54e-2)" "unprognostic (1.34e-2)" "prognostic unfavourable (9.26e-4)" "unprognostic (3.02e-1)" "unprognostic (2.42e-1)" "unprognostic (7.35e-2)" "unprognostic (1.55e-2)" 32.4 28.2 27.1 26.3 39.4 24.2 32.5 34.1 40.7 39.1 31.2 33.7 20.9 23.0 39.2 30.7 26.1 34.4 35.1 25.6 25.6 26.7 23.0 25.7 26.4 27.5 29.6 35.8 43.5 41.8 36.8 26.2 30.7 34.1 39.0 28.0 28.8 34.0 35.6 44.7 29.2 26.7 37.7 27.3 26.9 30.5 28.6 21.5 33.2 26.1 21.8 33.7 42.6 25.4 7.6 5.0 8.4 4.4 6.7 6.6 2.8 30.8 32.5 29.3 30.0 29.7 24.1 31.6 30.5 27.4 27.9 27.4 30.5 20.5 43.2 11.9 34.0 24.8 33.0 27.0 37.0 12.7 21.7 32.5 31.5 37.0 29.3 37.6 22.3 30.6 25.8 25.2 30.7 27.6 36.1 18.3 28.3 25.2 35.9 21.0 27.9 17.4 31.4 50.3 22.1 25.5 36.5 18.5 35.0 23.0 41.5 25.9 28.4 31.1 29.3 41.3 25.2 16.7 35.7 20.6 16.4 39.8 21.2 20.9 21.6 2.6 3.9 8.4 6.2 3.2 6.6 4.1 5.2 6.1 5.0 7.6 6.6 6.4 2.9 6.7 4.4 3.0 3.1 2.8 27.1 39.4 34.1 40.7 25.6 26.7 29.6 35.8 34.1 21.5 DDX43 "CT13, DKFZp434H2114, HAGE" ENSG00000080007 "DEAD-box helicase 43" Q9NXZ2 6 73394748-73417569 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 35.2" "Cell line enhanced" "Detected in some" "BEWO: 8.8;CAPAN-2: 14.8;HHSteC: 4.1;U-2 OS: 9.5" "Cancer enriched" "Detected in many" 15 "testis cancer: 13.0" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031381 Enhanced "HPA031381: AB_10601885" "unprognostic (4.03e-3)" "unprognostic (8.20e-2)" "unprognostic (2.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.19e-1)" "unprognostic (3.59e-4)" "unprognostic (1.64e-2)" "unprognostic (3.11e-2)" "unprognostic (1.20e-1)" "unprognostic (2.15e-1)" "unprognostic (3.12e-1)" "unprognostic (3.08e-1)" "unprognostic (1.19e-3)" "unprognostic (1.02e-1)" "unprognostic (2.68e-1)" "unprognostic (1.58e-1)" "unprognostic (8.78e-2)" 1.3 0.7 0.6 1.0 0.7 0.7 1.9 0.4 0.8 0.8 2.6 1.2 2.1 1.4 1.0 0.4 1.1 0.7 6.1 1.2 0.7 0.6 0.8 1.0 1.6 0.9 1.0 0.0 2.9 1.9 0.1 0.7 5.7 3.3 1.8 0.7 1.5 4.3 2.2 0.4 1.4 1.7 3.0 1.9 1.2 2.4 35.2 0.7 0.4 1.8 1.3 1.9 1.7 0.7 2.3 0.8 2.9 0.9 1.6 3.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.5 0.0 0.0 0.0 0.1 14.8 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 2.9 3.3 0.9 2.6 2.3 2.5 2.8 0.8 2.3 1.3 0.4 0.6 1.6 0.8 0.2 1.4 0.7 0.6 0.7 0.4 0.8 0.7 0.6 1.0 0.0 3.3 0.7 DDX46 "FLJ25329, KIAA0801, Prp5, PRPF5" ENSG00000145833 "DEAD-box helicase 46" Q7L014 5 134758771-134855133 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036554, HPA057501" Supported Enhanced "Nuclear speckles" "Nuclear speckles" "HPA036554: AB_10673621, HPA057501: AB_2683449" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "prognostic favourable (9.01e-6)" "unprognostic (7.00e-2)" "unprognostic (3.37e-2)" "unprognostic (1.71e-2)" "unprognostic (2.04e-3)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (5.05e-2)" "unprognostic (9.21e-2)" "unprognostic (6.02e-2)" "unprognostic (9.70e-3)" "unprognostic (4.36e-2)" "unprognostic (4.35e-2)" "unprognostic (1.64e-2)" "unprognostic (4.50e-2)" 22.2 21.8 18.8 29.4 23.8 22.7 22.7 39.0 24.8 25.1 21.4 17.5 18.6 19.0 26.8 19.8 23.7 21.0 15.8 18.3 17.7 13.0 22.9 22.7 21.6 26.6 22.9 15.1 25.8 24.2 27.2 37.5 22.1 21.7 19.0 24.2 12.8 23.9 23.3 46.6 26.3 23.0 24.6 27.8 30.0 22.2 17.8 25.9 40.4 22.1 21.0 29.1 23.1 28.9 27.0 23.5 34.6 19.9 19.4 20.4 9.7 25.7 23.6 16.8 21.9 6.6 7.4 23.3 17.2 13.4 18.3 20.6 35.7 18.8 32.5 14.9 11.5 16.0 24.7 16.4 21.6 21.8 22.5 39.1 25.8 14.4 5.7 35.4 21.1 6.6 9.0 19.2 10.9 14.4 33.2 14.0 13.5 12.3 30.4 13.8 23.2 10.7 26.6 44.0 16.4 10.0 22.3 20.0 19.1 24.1 11.5 12.5 17.9 20.3 17.9 19.4 13.5 14.8 34.1 11.0 29.9 43.1 13.4 33.8 12.2 25.7 19.9 27.6 20.0 17.5 18.0 22.0 19.6 19.8 15.2 27.0 20.4 20.3 34.6 19.4 15.7 23.5 17.1 9.7 18.8 23.8 39.0 24.8 17.7 13.0 22.9 15.1 21.7 25.9 DDX47 "DKFZp564O176, FLJ30012, HQ0256, RRP3" ENSG00000213782 "DEAD-box helicase 47" Q9H0S4 12 12813316-12829981 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014855 Approved Supported Nucleoli Nucleoli "HPA014855: AB_1847567" "unprognostic (3.14e-2)" "unprognostic (1.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.75e-2)" "unprognostic (2.38e-1)" "unprognostic (4.91e-2)" "unprognostic (5.84e-4)" "unprognostic (1.96e-1)" "unprognostic (1.11e-2)" "unprognostic (1.13e-3)" "unprognostic (2.79e-1)" "unprognostic (3.49e-3)" "unprognostic (6.55e-9)" "unprognostic (1.68e-1)" "unprognostic (1.27e-1)" "unprognostic (3.24e-1)" "unprognostic (8.20e-6)" 29.3 24.1 19.9 21.6 25.6 31.0 29.1 27.4 26.9 26.7 26.2 28.2 21.4 16.0 33.7 21.0 28.9 27.5 17.9 22.6 20.0 19.4 29.6 38.1 23.2 26.1 28.2 19.9 33.7 31.0 25.8 23.8 27.6 25.1 29.2 24.2 25.5 27.1 27.7 40.6 28.1 20.4 34.1 21.4 25.6 28.0 26.8 29.8 29.7 39.4 27.9 33.7 35.7 26.7 22.0 25.0 3.5 19.1 16.6 26.0 14.0 39.6 17.2 16.9 13.7 16.6 16.4 28.8 17.1 19.6 36.5 34.2 25.9 25.6 20.4 6.7 23.1 25.9 24.2 19.7 41.1 28.8 17.3 18.7 12.8 14.7 14.1 21.2 12.0 15.8 18.7 21.6 17.9 28.0 18.0 4.6 19.9 14.2 17.2 14.7 74.0 10.5 19.1 32.8 12.3 22.2 28.6 7.4 18.8 20.7 13.3 17.0 5.4 16.1 12.5 14.7 35.8 9.4 25.6 6.5 11.8 37.0 15.7 11.1 16.9 3.3 14.4 3.5 21.8 19.1 26.0 22.0 19.4 20.1 25.0 21.2 25.8 24.2 1.7 16.6 18.2 14.7 18.7 14.0 19.9 25.6 27.4 26.9 20.0 19.4 28.2 19.9 25.1 29.8 DDX49 "Dbp8, FLJ10432" ENSG00000105671 "DEAD-box helicase 49" Q9Y6V7 19 18919675-18928633 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041870, HPA048093" Enhanced Approved Nucleoli,Mitochondria Mitochondria Nucleoli "HPA041870: , HPA048093: " "unprognostic (3.51e-1)" "prognostic favourable (2.01e-6)" "unprognostic (2.28e-2)" "unprognostic (1.28e-1)" "unprognostic (8.56e-2)" "unprognostic (1.60e-2)" "prognostic unfavourable (7.05e-4)" "unprognostic (4.12e-2)" "unprognostic (2.41e-3)" "unprognostic (8.67e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "prognostic unfavourable (7.44e-5)" "unprognostic (3.93e-2)" "unprognostic (2.99e-2)" "unprognostic (4.97e-2)" "unprognostic (3.24e-1)" 14.8 16.8 17.6 17.3 16.9 28.3 18.0 17.0 30.7 15.3 15.8 19.0 14.8 19.5 15.6 13.2 23.4 16.5 12.2 18.2 19.2 12.9 15.5 25.6 13.0 19.3 15.7 14.8 15.7 26.8 13.0 11.1 23.3 16.2 15.5 10.3 13.5 24.3 15.8 27.2 23.6 18.7 12.7 16.8 16.7 15.7 19.7 16.3 23.4 18.8 16.6 18.7 16.4 15.6 8.2 25.0 13.5 19.5 14.1 14.0 9.7 15.8 16.5 6.7 21.0 9.8 7.9 25.2 10.1 6.9 17.9 14.5 18.8 16.1 20.8 30.9 10.0 13.7 14.9 13.9 5.1 6.3 39.6 10.2 17.9 16.3 23.3 26.2 14.2 15.8 13.4 14.2 15.1 8.1 19.2 14.9 6.3 35.5 18.9 12.2 21.8 40.3 21.0 11.2 22.5 9.6 10.0 23.6 24.3 13.3 13.2 16.1 13.6 12.6 10.4 8.7 9.9 31.5 16.5 19.6 23.4 19.0 11.1 30.2 13.6 10.5 17.7 13.5 12.8 19.5 10.6 8.1 9.7 9.6 25.0 8.2 9.7 10.2 7.9 14.1 12.6 11.2 14.0 9.7 17.6 16.9 17.0 30.7 19.2 12.9 15.7 14.8 16.2 16.3 DDX5 "G17P1, HLR1, p68" ENSG00000108654 "DEAD-box helicase 5" P17844 17 64499616-64508199 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005868, HPA020043" Supported Enhanced Nucleoplasm 150000 Nucleoplasm "CAB005868: AB_446484, HPA020043: AB_1847572" "unprognostic (6.64e-2)" "unprognostic (6.98e-2)" "prognostic favourable (2.12e-4)" "unprognostic (8.94e-2)" "unprognostic (5.08e-2)" "unprognostic (9.85e-2)" "unprognostic (5.80e-2)" "unprognostic (1.61e-2)" "unprognostic (3.17e-2)" "unprognostic (4.71e-2)" "unprognostic (3.03e-3)" "unprognostic (1.44e-1)" "unprognostic (4.00e-1)" "unprognostic (2.08e-1)" "unprognostic (2.37e-1)" "unprognostic (2.17e-1)" "unprognostic (9.28e-3)" 91.6 61.4 46.9 80.0 68.0 108.3 94.7 61.6 58.9 81.6 81.1 53.3 104.2 27.4 106.7 94.5 64.5 96.9 101.4 53.9 48.5 30.6 53.1 68.0 84.8 70.9 62.8 44.1 74.0 49.3 88.9 110.5 56.6 73.1 59.5 55.4 50.9 62.2 103.6 77.6 59.7 54.7 113.1 71.0 67.6 69.0 39.7 57.8 82.1 81.1 77.7 69.3 91.0 63.9 46.9 59.6 66.4 66.2 40.3 60.8 109.8 54.0 20.4 61.8 39.1 57.2 53.9 39.3 53.6 69.2 65.7 65.9 22.1 33.1 79.3 30.7 70.4 32.2 66.5 61.7 74.4 28.1 47.7 51.6 15.5 16.9 41.9 65.6 55.0 60.7 53.3 60.1 46.9 70.2 40.8 67.8 50.6 32.2 137.1 19.1 36.0 63.0 85.9 65.2 55.8 40.3 25.9 43.4 72.9 52.0 50.5 65.3 47.3 36.9 49.3 40.0 44.7 43.1 55.5 37.9 74.6 140.0 42.4 32.3 47.1 66.4 62.5 66.4 53.7 56.9 60.8 46.9 42.9 51.7 59.6 46.8 44.5 43.1 37.8 40.3 66.2 37.0 50.2 109.8 46.9 68.0 61.6 58.9 48.5 30.6 62.8 44.1 73.1 57.8 DDX50 "GU2, GUB, MGC3199, RH-II/GuB" ENSG00000107625 "DExD-box helicase 50" Q9BQ39 10 68901278-68946847 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037388, HPA037389, HPA058196" Approved Enhanced Nucleoli Nucleoli "HPA037388: AB_10671752, HPA037389: , HPA058196: " "unprognostic (2.05e-1)" "unprognostic (3.36e-1)" "unprognostic (9.90e-2)" "unprognostic (9.75e-2)" "unprognostic (1.29e-1)" "unprognostic (1.23e-1)" "unprognostic (1.47e-3)" "unprognostic (2.62e-1)" "unprognostic (1.97e-1)" "unprognostic (8.78e-2)" "unprognostic (4.57e-2)" "unprognostic (1.44e-1)" "unprognostic (4.22e-3)" "unprognostic (1.22e-2)" "unprognostic (2.38e-2)" "unprognostic (4.91e-2)" "unprognostic (1.02e-1)" 25.0 17.8 16.7 25.5 19.2 14.7 24.8 20.8 17.0 26.5 25.3 13.1 24.0 12.9 30.0 22.6 24.0 23.0 17.5 20.3 15.7 15.0 18.6 16.1 16.4 24.5 17.6 15.0 35.3 24.1 24.9 35.2 23.0 16.1 30.0 18.1 12.6 19.5 25.0 26.6 18.3 17.4 31.9 18.3 22.0 19.9 25.6 17.3 33.0 26.1 21.5 25.7 35.4 27.2 14.2 10.3 10.7 12.2 13.8 20.2 10.9 19.3 12.5 22.2 27.5 18.9 24.7 14.2 20.7 22.8 18.7 17.7 28.0 16.9 25.2 12.5 18.2 17.4 21.5 15.2 23.4 22.1 16.3 13.5 12.4 12.2 19.1 28.1 16.9 19.0 15.9 17.8 49.8 15.0 24.1 15.4 23.0 15.5 26.8 27.0 12.9 28.1 23.3 25.3 4.5 14.7 11.6 15.5 21.4 15.2 17.8 22.8 20.7 18.3 13.0 14.6 17.1 16.5 28.1 20.9 18.8 21.4 15.7 29.4 8.5 5.5 7.8 10.7 15.0 12.2 18.3 13.6 18.5 15.4 10.3 14.2 20.2 17.7 2.7 13.8 9.6 10.2 16.1 10.9 16.7 19.2 20.8 17.0 15.7 15.0 17.6 15.0 16.1 17.3 DDX51 ENSG00000185163 "DEAD-box helicase 51" Q8N8A6 12 132136594-132144335 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039503 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol "Nucleoplasm, Nucleoli" Cytosol "HPA039503: AB_10796328" "unprognostic (2.84e-3)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" "unprognostic (2.84e-1)" "unprognostic (8.66e-2)" "unprognostic (4.00e-2)" "prognostic unfavourable (4.73e-4)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (4.88e-1)" "unprognostic (3.05e-3)" "unprognostic (5.31e-2)" "unprognostic (3.97e-2)" "unprognostic (2.48e-1)" "unprognostic (4.69e-2)" "unprognostic (3.28e-1)" "unprognostic (1.65e-3)" 10.5 8.5 12.7 12.7 17.1 17.2 10.3 23.5 18.9 8.8 8.4 11.8 10.6 7.8 11.5 12.2 8.5 12.4 10.0 8.1 11.6 9.9 9.5 7.2 8.9 11.1 10.5 16.9 19.6 14.8 10.1 9.8 7.2 11.8 9.3 7.3 8.9 10.7 12.4 13.8 18.0 8.2 10.4 10.5 10.6 9.3 6.7 12.0 9.5 9.9 7.1 10.4 9.3 8.6 2.5 2.3 2.6 2.1 1.6 2.0 1.0 6.2 10.1 4.2 5.3 4.0 3.9 8.0 4.8 2.9 7.1 3.0 6.2 3.1 10.9 4.2 2.9 6.6 10.4 7.7 3.5 2.6 10.1 12.9 5.4 2.0 4.8 9.0 7.5 3.4 5.7 4.0 3.6 3.8 9.5 3.6 2.1 6.1 10.9 18.4 7.4 17.3 13.0 5.7 12.1 4.8 4.9 10.3 5.4 5.2 7.5 5.3 6.6 8.3 6.6 2.7 8.2 6.6 11.0 10.1 5.9 12.7 5.6 6.8 6.3 1.1 2.1 1.2 2.0 1.0 0.7 1.5 1.3 0.9 0.6 2.5 1.2 1.6 2.6 1.6 1.0 2.3 0.6 1.0 12.7 17.1 23.5 18.9 11.6 9.9 10.5 16.9 11.8 12.0 DDX52 ROK1 ENSG00000278053 "DExD-box helicase 52" Q9Y2R4 17 37609739-37643464 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056173 Uncertain Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA056173: " "unprognostic (1.05e-2)" "unprognostic (1.85e-1)" "prognostic favourable (9.41e-4)" "unprognostic (4.26e-2)" "unprognostic (9.96e-3)" "unprognostic (6.77e-2)" "prognostic unfavourable (2.44e-6)" "unprognostic (5.10e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (6.95e-2)" "unprognostic (5.58e-1)" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" 6.4 4.5 4.3 5.3 5.5 9.1 4.6 8.1 6.5 6.9 6.1 4.8 5.0 5.9 7.8 10.7 6.7 3.5 5.0 3.0 4.5 9.4 7.1 4.2 5.1 5.4 3.1 6.3 4.4 6.2 8.8 5.8 6.5 6.1 6.0 4.0 4.1 4.8 6.7 6.0 10.6 4.8 6.2 5.7 4.8 4.8 4.9 8.7 5.7 5.8 6.1 6.0 6.9 4.0 5.7 3.5 4.2 3.5 4.7 1.5 4.7 9.8 1.0 9.7 5.5 4.9 4.2 6.5 5.8 8.5 8.3 5.0 1.8 2.7 4.5 4.3 4.4 10.8 7.1 11.4 6.5 12.2 6.0 6.2 4.0 5.4 7.7 3.2 5.1 7.2 5.5 6.9 9.8 0.8 1.8 5.0 1.5 11.7 4.0 5.5 0.4 7.5 8.5 5.0 9.7 5.4 7.2 5.8 7.7 1.8 4.7 3.4 6.0 6.5 7.0 4.3 3.5 7.3 2.3 3.8 5.4 5.7 4.9 5.5 3.4 3.2 3.5 4.2 4.2 3.3 3.6 4.0 3.5 2.3 4.0 3.4 4.7 2.8 3.5 2.4 5.7 3.1 1.5 DDX53 "CAGE, CT26" ENSG00000184735 "DEAD-box helicase 53" Q86TM3 X 22999961-23003589 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 11.5" "Cell line enhanced" "Detected in some" "K-562: 6.2;RPMI-8226: 3.2;U-2197: 2.1;U-266/84: 14.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003186 Supported Nucleoplasm,Nucleoli,Cytosol Nucleoplasm "Nucleoli, Cytosol" "HPA003186: AB_1078637" "unprognostic (5.76e-1)" "unprognostic (1.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.4 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DDX54 "APR-5, DP97, MGC2835" ENSG00000123064 "DEAD-box helicase 54" Q8TDD1 12 113157174-113185479 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028244, HPA070786" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA028244: AB_10603885, HPA070786: " "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (8.54e-2)" "unprognostic (8.57e-2)" "unprognostic (6.39e-2)" "prognostic unfavourable (1.39e-4)" "unprognostic (2.23e-2)" "unprognostic (1.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.83e-2)" "unprognostic (1.15e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.22e-1)" "unprognostic (1.24e-1)" 17.2 17.6 9.2 20.7 12.8 25.4 17.2 9.9 13.6 17.9 16.4 12.4 18.1 20.3 18.0 19.4 19.5 17.2 17.9 20.1 8.8 7.9 22.3 28.6 14.0 19.9 8.1 9.4 22.4 27.0 18.3 7.4 22.6 10.0 16.6 9.0 13.4 17.4 13.9 45.4 18.7 19.4 14.8 8.1 22.2 16.1 11.4 8.6 26.6 23.1 21.6 22.2 16.7 17.5 12.1 13.3 8.0 15.2 11.9 13.0 10.0 26.4 27.7 10.3 19.0 6.9 8.3 26.7 14.4 13.4 19.7 10.8 28.5 12.9 34.3 16.9 12.0 19.7 18.3 18.7 7.5 19.7 22.5 20.6 14.9 19.4 12.2 34.3 24.4 13.7 14.8 19.0 11.8 16.1 29.8 12.3 10.1 24.5 29.5 49.0 24.1 19.7 21.9 15.3 35.0 10.7 27.7 13.4 12.2 20.4 31.3 13.0 26.8 26.9 11.9 16.7 18.7 19.8 30.0 18.0 20.5 38.6 14.7 19.2 17.5 8.0 10.0 2.3 12.4 15.2 13.0 11.6 11.4 12.2 13.3 12.1 11.8 12.5 0.6 11.9 9.8 10.0 9.4 10.0 9.2 12.8 9.9 13.6 8.8 7.9 8.1 9.4 10.0 8.6 DDX55 KIAA1595 ENSG00000111364 "DEAD-box helicase 55" Q8NHQ9 12 123602077-123620941 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039962, HPA044101" Approved Enhanced Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA039962: , HPA044101: " "unprognostic (1.14e-1)" "unprognostic (2.30e-2)" "unprognostic (2.29e-1)" "unprognostic (3.71e-3)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "prognostic unfavourable (2.11e-9)" "unprognostic (1.60e-1)" "unprognostic (4.49e-2)" "unprognostic (7.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.67e-3)" "prognostic unfavourable (8.97e-12)" "unprognostic (9.15e-3)" "unprognostic (2.94e-1)" "unprognostic (3.47e-2)" "unprognostic (1.23e-3)" 15.0 13.5 12.3 16.4 14.0 27.7 16.3 21.4 13.9 13.0 13.2 15.7 16.2 12.0 14.7 13.2 14.2 15.0 11.8 8.8 11.4 10.9 10.2 17.8 11.2 19.9 15.6 10.3 17.5 25.9 13.8 20.3 12.3 14.4 14.4 14.5 11.9 15.2 12.6 12.6 21.4 12.9 11.9 10.5 18.8 11.6 11.2 14.8 16.9 12.2 12.5 16.5 11.9 23.1 13.4 12.8 7.3 10.0 12.2 15.7 8.5 10.0 14.2 10.9 11.0 9.4 7.5 16.5 12.4 4.6 11.1 7.7 16.1 7.3 14.8 10.0 5.4 12.3 16.6 9.2 13.0 11.1 15.1 20.0 15.7 11.9 7.1 24.6 15.8 6.2 9.8 13.1 15.3 7.9 20.4 7.9 7.8 10.3 24.1 33.5 16.9 14.2 18.2 11.7 9.7 7.8 17.4 13.0 10.8 10.1 13.1 16.9 23.4 16.0 8.1 9.6 12.6 15.6 15.3 14.6 18.0 26.9 9.1 17.7 16.3 2.8 9.2 7.3 12.0 10.0 12.7 13.4 11.6 12.5 7.5 11.3 15.7 14.7 5.6 12.2 5.9 12.8 9.1 8.5 12.3 14.0 21.4 13.9 11.4 10.9 15.6 10.3 14.4 14.8 DDX56 NOH61 ENSG00000136271 "DEAD-box helicase 56" Q9NY93 7 44565417-44575051 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019749, CAB037320" Uncertain Supported Nucleoli Nucleoli "CAB037320: , HPA019749: AB_1847579" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (5.00e-2)" "unprognostic (1.93e-1)" "unprognostic (6.08e-3)" "unprognostic (2.12e-3)" "prognostic unfavourable (1.38e-5)" "unprognostic (5.17e-2)" "unprognostic (2.76e-1)" "unprognostic (7.07e-2)" "unprognostic (1.00e-2)" "unprognostic (6.01e-3)" "prognostic unfavourable (8.41e-7)" "unprognostic (2.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.50e-1)" "unprognostic (4.90e-2)" 12.8 12.0 10.3 12.4 11.9 12.4 9.2 13.6 18.9 11.9 10.0 12.2 8.6 11.9 12.8 10.3 13.1 12.6 12.5 9.3 10.6 9.9 17.7 29.2 8.9 13.2 10.4 9.3 15.0 22.5 13.1 11.9 12.3 12.2 14.1 9.0 11.0 16.9 11.5 16.9 16.3 11.4 8.4 8.8 12.1 10.6 14.6 10.9 14.5 13.8 16.7 15.1 9.2 10.3 12.8 16.0 6.9 16.5 15.7 12.3 12.7 7.6 20.4 1.5 4.4 2.0 2.0 6.8 7.2 3.7 8.2 7.3 13.2 7.5 13.5 9.4 2.7 13.1 3.3 7.2 1.5 5.0 20.7 8.8 12.9 10.0 3.5 9.3 4.9 2.9 5.2 7.3 4.6 4.2 18.2 3.8 5.3 10.0 4.6 8.6 11.1 19.2 3.8 7.2 5.3 4.7 8.1 5.2 8.4 9.6 14.9 5.5 10.8 9.6 8.8 6.8 9.8 4.6 18.2 12.4 18.9 19.3 7.5 11.4 9.5 6.9 11.8 4.3 9.9 15.3 12.3 11.5 10.7 11.1 16.0 12.8 12.3 10.3 0.4 15.7 16.5 7.7 10.1 12.7 10.3 11.9 13.6 18.9 10.6 9.9 10.4 9.3 12.2 10.9 DDX58 "DKFZp434J1111, FLJ13599, RIG-I" ENSG00000107201 "DExD/H-box helicase 58" O95786 9 32455705-32526324 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "BJ hTERT+ SV40 Large T+: 44.8;BJ hTERT+ SV40 Large T+ RasG12V: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012643, HPA047193" Uncertain Approved "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "CAB012643: , HPA047193: " "unprognostic (1.10e-1)" "unprognostic (4.65e-2)" "unprognostic (6.56e-2)" "prognostic unfavourable (5.46e-4)" "unprognostic (2.45e-1)" "unprognostic (2.37e-1)" "unprognostic (8.15e-2)" "unprognostic (4.57e-2)" "unprognostic (2.82e-1)" "unprognostic (6.48e-3)" "unprognostic (1.00e-2)" "unprognostic (3.35e-1)" "prognostic unfavourable (4.66e-4)" "unprognostic (2.22e-2)" "unprognostic (3.68e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" 27.7 8.2 5.7 14.5 7.9 5.6 11.3 4.2 5.7 9.9 9.5 5.2 9.1 7.2 12.7 11.7 10.8 7.6 10.3 7.1 6.0 5.1 14.7 8.5 13.7 14.3 6.3 4.5 9.2 7.7 6.6 10.2 14.8 7.5 12.1 8.1 5.5 12.4 5.8 8.3 10.7 16.1 10.8 7.7 13.8 8.0 4.5 6.4 35.4 13.0 7.4 9.7 9.9 9.4 4.9 2.0 24.8 5.7 6.1 6.5 3.0 2.9 1.1 1.6 0.9 3.8 4.0 2.5 1.8 8.8 44.8 46.8 1.2 2.6 0.8 3.2 1.6 2.4 1.7 1.9 6.3 7.2 0.6 2.8 2.5 2.0 3.1 1.8 2.2 2.8 0.7 5.2 1.5 8.1 0.6 0.6 5.9 0.4 2.5 4.6 1.3 1.2 2.4 1.2 0.3 6.8 1.6 1.2 0.7 2.6 1.1 4.9 1.9 1.5 9.3 1.3 1.3 1.1 0.9 0.1 0.5 0.5 2.0 0.8 0.9 8.5 3.8 10.3 6.2 5.7 5.5 4.8 5.6 5.6 2.0 4.9 5.1 5.6 24.8 6.1 3.9 0.1 6.5 3.0 5.7 7.9 4.2 5.7 6.0 5.1 6.3 4.5 7.5 6.4 DDX59 "DKFZP564B1023, ZNHIT5" ENSG00000118197 "DEAD-box helicase 59" Q5T1V6 1 200623896-200669969 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Ciliopathy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047166 Approved Approved "Nucleoplasm,Actin filaments" "Nucleoplasm, Actin filaments" "HPA047166: AB_2679966" "unprognostic (1.99e-1)" "unprognostic (1.60e-1)" "unprognostic (3.44e-2)" "unprognostic (4.87e-2)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" "unprognostic (4.83e-2)" "unprognostic (3.40e-3)" "unprognostic (2.43e-3)" "unprognostic (4.16e-1)" "unprognostic (2.16e-1)" "prognostic unfavourable (9.02e-4)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (6.66e-2)" "unprognostic (5.98e-2)" 14.0 14.4 12.1 16.4 14.8 23.7 22.7 16.7 11.2 14.5 11.6 10.8 12.6 8.1 15.8 17.6 12.0 13.8 11.4 18.0 12.0 9.9 13.6 15.1 11.8 15.1 15.1 6.7 17.1 21.6 13.9 10.7 46.5 12.8 14.1 12.5 15.0 19.4 12.9 28.6 21.5 12.4 14.0 17.2 20.9 10.4 9.9 14.5 18.5 15.1 10.1 13.2 12.8 12.7 12.2 9.5 23.1 16.2 12.4 15.6 7.9 9.2 10.8 12.5 10.5 5.7 9.8 28.0 10.5 9.4 11.2 9.1 3.4 11.0 9.5 5.3 8.3 8.9 7.0 10.7 8.0 29.9 7.2 7.2 13.8 10.0 11.4 10.4 13.4 10.6 16.2 8.5 23.2 8.6 9.1 14.1 10.9 10.7 6.2 15.6 13.2 8.8 5.3 8.7 18.2 12.0 10.9 7.6 19.8 16.6 17.3 18.4 14.9 14.6 7.7 9.5 5.4 9.3 10.8 10.8 14.0 12.6 9.1 6.6 16.2 23.1 10.3 19.0 13.0 8.9 10.6 12.2 10.9 11.7 8.5 11.5 11.3 10.3 18.2 12.4 16.2 9.5 15.6 7.9 12.1 14.8 16.7 11.2 12.0 9.9 15.1 6.7 12.8 14.5 DDX6 "HLR2, RCK" ENSG00000110367 "DEAD-box helicase 6" P26196 11 118747766-118791149 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004668, HPA024201, HPA026644" Approved Supported "Cytosol,Cytoplasmic bodies" "Cytoplasmic bodies" Cytosol "CAB004668: AB_436960, HPA024201: AB_10603562, HPA026644: AB_1847582" "unprognostic (1.26e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-1)" "unprognostic (3.40e-2)" "unprognostic (4.12e-2)" "unprognostic (5.82e-2)" "prognostic unfavourable (6.56e-4)" "unprognostic (3.43e-1)" "unprognostic (1.48e-2)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (7.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.91e-3)" "unprognostic (1.88e-1)" "unprognostic (9.58e-2)" "unprognostic (4.55e-2)" 29.8 23.0 25.0 24.1 41.0 43.3 25.1 41.9 39.2 26.9 23.2 29.4 14.5 17.1 30.1 22.9 31.8 23.4 17.5 26.8 25.5 25.1 22.8 24.6 23.4 32.2 21.9 27.1 38.2 27.9 30.9 43.2 26.1 29.6 24.9 20.8 25.4 26.8 22.9 43.8 23.9 24.1 27.8 30.4 30.6 21.2 19.9 24.0 46.0 27.9 19.4 42.8 33.0 25.7 12.2 6.5 17.8 10.3 7.2 12.6 5.7 11.7 16.0 25.8 25.4 22.6 23.3 16.9 15.9 20.9 14.8 14.1 23.3 18.1 26.9 16.7 26.0 18.8 30.1 23.2 23.9 20.2 6.0 51.8 10.3 18.9 15.0 37.1 20.0 24.6 17.1 21.9 35.7 23.6 23.8 39.1 20.9 32.0 27.0 17.2 18.3 11.8 29.8 20.8 21.5 17.3 30.4 17.1 23.6 30.0 24.1 9.5 28.2 14.6 26.9 24.6 13.5 14.0 16.0 12.2 15.8 32.1 9.8 17.9 21.0 10.5 4.1 11.6 10.1 5.7 12.6 11.4 9.9 10.4 4.7 12.2 12.4 10.8 17.8 7.2 10.3 6.5 8.9 5.7 25.0 41.0 41.9 39.2 25.5 25.1 21.9 27.1 29.6 24.0 DDX60 FLJ20035 ENSG00000137628 "DExD/H-box helicase 60" Q8IY21 4 168216293-168318807 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 22.5;BJ hTERT+ SV40 Large T+ RasG12V: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA046952 Approved Supported "Intermediate filaments,Cytosol" Cytosol "Intermediate filaments" "HPA046952: AB_10963572" "unprognostic (4.05e-2)" "unprognostic (2.87e-1)" "unprognostic (7.22e-3)" "unprognostic (7.71e-2)" "unprognostic (2.30e-1)" "unprognostic (2.65e-2)" "unprognostic (1.50e-2)" "unprognostic (3.15e-2)" "unprognostic (3.06e-1)" "unprognostic (8.69e-3)" "prognostic unfavourable (3.35e-4)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (2.48e-1)" "unprognostic (3.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.44e-1)" 18.0 8.3 4.1 18.5 5.0 4.4 9.0 1.3 3.8 11.4 14.8 4.3 5.1 8.8 10.8 15.2 10.7 8.1 11.5 8.5 3.7 3.5 10.0 8.8 21.6 18.7 4.2 3.2 20.3 5.5 8.8 6.7 25.5 5.6 11.6 14.3 9.0 15.6 6.2 5.6 7.9 16.7 11.2 6.1 18.9 29.2 5.7 3.9 23.2 14.5 6.0 9.3 8.2 7.2 4.1 2.5 3.2 6.3 7.6 10.0 3.5 5.5 1.2 2.8 1.1 2.1 7.7 3.1 1.8 13.5 22.5 21.8 0.0 12.2 0.0 1.1 3.0 4.6 0.3 4.5 6.5 4.3 0.5 8.7 4.8 0.0 10.1 3.2 2.2 6.9 1.9 5.7 1.3 8.4 0.0 1.6 2.8 0.3 4.9 2.4 0.5 1.6 3.3 1.4 0.1 6.6 3.4 0.6 0.6 3.5 0.9 13.6 0.9 4.1 5.6 1.4 1.4 0.5 1.4 1.0 0.2 0.0 4.3 3.8 3.9 3.2 2.8 2.6 8.5 5.1 10.0 4.1 6.7 8.0 2.5 3.3 6.8 8.5 2.8 7.6 6.3 0.2 5.5 3.5 4.1 5.0 1.3 3.8 3.7 3.5 4.2 3.2 5.6 3.9 DDX60L FLJ31033 ENSG00000181381 "DExD/H-box 60 like" Q5H9U9 4 168356735-168537786 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 22.5" "Group enriched" "Detected in all" 4 "granulocytes: 22.5;monocytes: 7.8" "HPA043211, HPA055501" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA043211: AB_10794390, HPA055501: " "unprognostic (8.86e-2)" "unprognostic (2.77e-1)" "unprognostic (1.16e-1)" "unprognostic (2.45e-1)" "unprognostic (2.38e-1)" "unprognostic (3.20e-2)" "unprognostic (1.05e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (4.19e-2)" "prognostic unfavourable (3.04e-5)" "unprognostic (1.70e-1)" "prognostic unfavourable (2.94e-4)" "unprognostic (1.13e-1)" "unprognostic (8.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.69e-1)" 12.7 5.0 2.8 13.1 3.1 33.0 9.9 1.4 3.2 7.2 8.4 3.2 2.7 6.0 9.2 7.9 3.8 6.9 6.7 6.0 2.4 2.4 4.5 6.0 25.8 17.7 3.8 1.4 7.3 5.1 4.4 5.2 32.6 3.4 5.0 6.5 6.8 7.0 5.7 3.3 4.3 14.0 5.3 4.2 11.9 9.5 2.7 3.1 25.3 5.8 3.5 8.1 4.9 6.8 1.6 2.4 22.5 7.8 1.7 3.7 1.6 6.0 3.6 1.4 0.6 3.7 10.7 7.0 6.1 13.0 23.1 16.1 0.0 14.4 0.1 0.3 6.2 2.4 0.6 3.7 6.7 3.5 0.5 13.4 4.0 0.3 4.5 5.5 3.4 3.0 1.1 8.3 0.7 16.2 0.2 0.1 14.8 0.1 4.9 3.5 0.3 3.0 2.7 3.1 0.0 2.2 3.6 0.2 1.9 10.9 1.3 6.1 1.0 7.7 17.3 1.2 8.2 2.9 2.1 5.9 0.9 0.0 4.1 16.3 1.7 1.6 4.0 3.5 2.7 6.3 3.7 0.9 2.7 2.7 2.4 1.6 2.2 2.3 22.5 1.7 7.8 0.0 3.6 1.6 2.8 3.1 1.4 3.2 2.4 2.4 3.8 1.4 3.4 3.1 DESI2 "C1orf121, CGI-146, FAM152A, FLJ21998, PNAS-4, PPPDE1" ENSG00000121644 "Desumoylating isopeptidase 2" Q9BSY9 1 244652935-244709033 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049950 Approved Vesicles Vesicles "HPA049950: " "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (5.40e-2)" "unprognostic (1.95e-2)" "unprognostic (7.62e-2)" "unprognostic (1.38e-3)" "unprognostic (1.51e-1)" "unprognostic (4.47e-3)" "unprognostic (1.45e-1)" "prognostic unfavourable (4.25e-5)" "unprognostic (4.52e-2)" "unprognostic (8.27e-2)" "unprognostic (2.27e-2)" "unprognostic (9.49e-2)" 16.4 13.3 6.4 16.1 12.9 10.5 19.9 17.4 6.5 18.5 19.4 7.6 14.6 10.9 27.7 12.8 14.7 12.4 12.7 27.6 6.5 5.8 9.6 13.5 28.4 11.5 7.7 3.2 16.3 10.0 14.8 11.8 20.4 6.9 14.9 13.1 17.8 12.1 14.8 16.2 11.6 17.5 23.2 6.6 14.3 14.9 49.2 7.4 16.8 25.8 14.5 14.7 16.8 14.4 8.0 4.8 9.1 4.0 3.9 5.6 1.2 24.2 9.1 17.9 15.4 20.5 21.5 22.5 14.1 24.7 14.1 13.0 16.1 11.6 43.3 19.4 17.6 10.7 21.8 16.0 19.5 14.8 16.0 11.0 6.8 12.0 18.0 18.8 13.3 14.9 21.8 18.8 23.7 19.8 16.5 24.1 21.1 4.2 17.1 10.1 40.5 22.1 12.3 27.1 16.4 10.8 10.2 15.9 21.3 20.0 10.0 17.6 10.4 14.3 21.4 16.1 16.8 21.7 24.5 24.5 31.5 25.5 13.0 20.3 29.3 4.6 3.0 9.1 4.0 3.9 4.2 8.0 4.2 5.6 4.8 4.7 5.5 5.4 2.5 3.9 4.0 4.2 5.2 1.2 6.4 12.9 17.4 6.5 6.5 5.8 7.7 3.2 6.9 7.4 DHX15 "DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p" ENSG00000109606 "DEAH-box helicase 15" O43143 4 24517441-24584550 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047047 Approved Enhanced "Nuclear speckles" 30000 "Nuclear speckles" "HPA047047: " "unprognostic (4.46e-3)" "unprognostic (2.47e-2)" "prognostic favourable (5.74e-4)" "unprognostic (3.35e-1)" "unprognostic (5.30e-2)" "unprognostic (5.74e-2)" "unprognostic (2.06e-3)" "unprognostic (5.53e-3)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (8.68e-3)" "unprognostic (7.77e-3)" "unprognostic (2.51e-3)" "unprognostic (2.19e-1)" "unprognostic (1.59e-1)" "unprognostic (5.41e-3)" 34.3 29.6 23.2 32.1 27.5 42.5 33.0 38.0 27.6 31.1 31.9 29.5 24.1 22.8 37.5 23.4 40.8 30.6 22.9 32.6 22.8 18.8 30.0 29.5 31.2 34.7 29.4 17.7 36.5 35.9 42.5 32.8 39.2 27.4 28.2 37.7 22.4 34.1 24.9 36.5 36.0 30.7 30.7 22.8 32.4 32.4 21.0 27.9 58.3 33.5 31.6 43.0 35.4 35.7 20.3 26.7 31.4 24.1 24.5 28.8 17.7 29.6 29.1 48.3 23.9 23.7 23.2 28.8 34.6 30.5 36.6 36.4 29.5 36.0 54.5 21.4 28.3 24.9 62.0 41.6 57.0 20.0 29.4 47.3 31.9 23.8 14.0 48.7 32.7 19.4 25.1 35.6 24.1 30.5 44.3 22.1 41.4 22.4 63.8 32.6 52.5 26.5 42.1 56.7 25.5 43.6 42.7 41.5 26.0 26.8 25.9 24.3 28.3 25.3 27.8 31.0 20.4 23.4 40.3 16.7 28.1 65.2 20.8 39.8 36.9 31.4 20.2 18.8 21.1 20.6 28.8 19.9 23.6 24.5 26.7 20.3 24.9 23.7 9.7 24.5 24.1 17.8 25.8 17.7 23.2 27.5 38.0 27.6 22.8 18.8 29.4 17.7 27.4 27.9 DHX16 "DBP2, DDX16, Prp2, PRPF2" ENSG00000204560 "DEAH-box helicase 16" O60231 6 30653119-30673037 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051455 Supported Supported Nucleoplasm Nucleoplasm "HPA051455: " "unprognostic (7.04e-2)" "unprognostic (1.37e-1)" "unprognostic (7.29e-2)" "unprognostic (7.46e-2)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (4.36e-3)" "unprognostic (1.13e-1)" "unprognostic (2.66e-2)" "unprognostic (3.11e-1)" "unprognostic (8.58e-2)" "unprognostic (1.24e-2)" "unprognostic (9.77e-3)" "unprognostic (4.42e-2)" "unprognostic (1.51e-1)" "unprognostic (2.64e-1)" "unprognostic (8.73e-3)" 12.8 15.8 12.7 16.8 14.0 12.1 14.4 16.8 14.9 13.3 16.2 12.3 15.8 19.3 16.3 13.3 14.9 14.4 14.6 12.4 11.4 7.1 18.0 19.2 13.9 18.2 13.6 8.6 15.6 19.1 24.3 16.6 11.3 13.5 16.4 13.6 14.4 18.0 18.2 23.2 18.4 19.8 16.4 11.0 22.6 14.9 36.8 14.9 18.8 21.6 12.1 16.5 13.2 15.3 4.5 5.9 8.7 7.6 7.1 5.8 4.4 9.6 4.0 5.9 9.2 6.8 4.6 7.1 8.0 6.4 11.6 9.0 9.1 4.0 7.3 7.5 7.1 9.3 9.7 7.2 9.3 10.3 8.0 7.2 7.4 5.1 5.9 18.2 9.7 4.2 7.1 9.4 8.1 3.5 12.0 7.2 5.7 8.0 5.2 9.2 5.6 5.6 8.7 6.3 7.9 6.1 7.6 7.1 5.7 8.9 9.4 6.5 7.2 5.5 3.8 7.5 5.1 7.2 11.7 8.6 13.3 7.2 3.6 10.0 9.5 6.0 6.0 8.7 5.8 7.5 5.3 4.4 5.3 4.8 5.9 4.5 4.4 5.0 5.8 7.1 7.6 4.8 5.1 4.4 12.7 14.0 16.8 14.9 11.4 7.1 13.6 8.6 13.5 14.9 DHX29 DDX29 ENSG00000067248 "DExH-box helicase 29" Q7Z478 5 55256245-55307722 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Helicase, Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038317, HPA038318" Approved Approved Cytosol "Intracellular and membrane" Cytosol "HPA038317: AB_10673169, HPA038318: AB_10672589" "unprognostic (3.43e-2)" "unprognostic (5.09e-1)" "unprognostic (2.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (2.37e-3)" "unprognostic (1.72e-1)" "unprognostic (6.66e-2)" "unprognostic (1.76e-2)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.57e-3)" "unprognostic (4.01e-1)" "unprognostic (3.85e-1)" "unprognostic (4.78e-3)" "unprognostic (9.40e-2)" 14.6 16.2 15.1 12.2 16.6 9.8 16.3 22.0 16.9 17.3 18.4 9.2 20.2 11.3 17.4 12.8 18.5 13.6 11.7 22.1 12.8 9.6 22.4 20.6 15.2 11.8 13.7 11.9 13.8 15.3 30.3 30.7 17.7 16.3 18.9 13.3 7.8 15.2 24.3 31.8 15.9 14.7 18.5 13.1 14.3 14.8 10.2 16.6 15.6 20.9 12.0 11.9 19.9 14.4 18.5 25.9 32.4 19.6 16.0 18.8 6.3 22.2 15.7 13.1 17.3 21.6 18.2 16.1 23.8 18.8 17.5 18.2 12.8 14.6 13.0 21.7 26.7 16.5 20.6 23.1 25.2 5.3 11.6 12.0 14.6 8.9 12.4 8.0 12.8 15.9 14.3 18.7 11.3 23.0 14.6 10.0 20.9 15.4 14.0 8.0 11.1 17.6 6.8 20.6 21.5 15.2 15.4 12.2 8.3 23.6 13.0 11.8 18.4 14.8 20.1 16.1 13.6 14.4 17.3 9.6 14.4 17.7 19.8 13.9 18.1 32.4 16.3 15.9 13.5 16.4 15.1 18.5 16.9 15.0 12.1 17.6 18.8 15.8 15.2 16.0 19.6 25.9 13.9 6.3 15.1 16.6 22.0 16.9 12.8 9.6 13.7 11.9 16.3 16.6 DHX30 "DDX30, FLJ11214, KIAA0890" ENSG00000132153 "DExH-box helicase 30" Q7L2E3 3 47802909-47850195 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034806 Supported Supported Mitochondria,Cytosol Mitochondria Cytosol "HPA034806: AB_10601364" "unprognostic (2.00e-1)" "unprognostic (8.37e-2)" "unprognostic (3.27e-1)" "unprognostic (2.14e-2)" "unprognostic (3.04e-1)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "prognostic favourable (1.37e-6)" "unprognostic (4.12e-2)" "unprognostic (1.43e-1)" "unprognostic (2.81e-1)" "unprognostic (2.22e-1)" 18.4 18.7 22.1 18.5 31.1 23.6 18.3 31.2 43.5 22.3 17.8 26.9 15.5 17.3 23.3 14.8 21.0 24.8 17.9 21.3 19.1 19.8 18.6 19.3 16.7 22.0 20.4 28.0 27.1 21.2 37.3 24.8 20.6 23.6 20.4 13.0 22.0 20.4 23.6 27.1 26.2 16.1 18.8 15.3 21.2 18.7 54.4 18.4 23.8 20.1 15.2 16.9 18.6 17.6 9.9 13.0 9.8 10.5 8.2 16.1 11.6 8.1 20.7 20.5 21.1 9.5 7.9 14.0 15.4 13.2 26.6 19.2 23.8 17.4 26.5 12.1 15.0 12.5 30.3 21.5 9.5 18.0 36.3 23.1 30.5 23.2 16.5 21.5 24.0 13.8 13.7 28.1 19.8 17.3 32.5 17.1 12.4 22.0 27.3 23.6 22.8 35.4 18.2 11.0 23.5 13.3 20.7 16.9 22.5 15.0 21.4 11.1 15.0 22.6 12.0 16.1 20.9 18.1 28.2 20.7 25.8 24.1 16.7 18.8 19.9 9.8 10.1 7.2 15.0 10.3 13.0 9.9 12.7 16.1 13.0 9.3 12.1 13.0 1.5 8.2 10.5 7.8 14.3 11.6 22.1 31.1 31.2 43.5 19.1 19.8 20.4 28.0 23.6 18.4 DHX32 "DDX32, DHLP1, FLJ10694, FLJ10889" ENSG00000089876 "DEAH-box helicase 32 (putative)" Q7L7V1 10 125836337-125896436 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048872 Approved "HPA048872: " "unprognostic (1.05e-1)" "unprognostic (3.02e-1)" "unprognostic (3.97e-2)" "unprognostic (6.40e-2)" "unprognostic (2.40e-1)" "unprognostic (3.57e-1)" "unprognostic (1.55e-2)" "unprognostic (9.88e-2)" "unprognostic (2.85e-1)" "unprognostic (6.89e-3)" "prognostic unfavourable (9.49e-5)" "prognostic unfavourable (6.34e-4)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (8.62e-2)" "unprognostic (1.98e-1)" "unprognostic (2.49e-1)" 15.4 16.3 7.8 10.2 9.7 4.0 18.0 7.3 11.5 10.5 20.1 12.1 11.2 11.4 10.6 14.0 20.6 8.6 13.1 27.3 7.6 7.5 12.1 14.5 10.1 16.8 10.3 7.0 18.1 23.5 11.7 9.5 19.3 8.9 13.1 24.5 12.8 17.9 8.4 16.0 18.5 16.1 9.1 9.8 12.2 21.7 20.6 9.5 8.0 13.6 10.7 10.0 13.0 12.6 6.8 2.3 3.2 3.5 4.5 5.3 0.9 27.1 15.0 10.1 20.8 13.6 12.5 18.2 12.1 28.0 11.0 12.4 3.5 27.0 0.1 9.1 14.0 19.9 4.6 20.3 9.2 13.7 9.0 3.3 7.7 5.3 15.0 6.5 11.2 12.3 21.3 10.8 24.4 16.0 9.3 0.1 10.6 12.2 0.1 10.4 7.7 10.4 0.1 16.5 5.9 16.0 12.7 1.4 7.4 11.2 20.1 16.5 7.4 5.8 14.3 8.6 5.3 10.9 10.6 10.8 10.4 0.2 15.6 0.1 4.4 0.3 3.0 3.2 2.7 3.5 2.2 6.8 1.3 1.1 2.3 3.2 5.3 2.1 0.1 4.5 1.7 1.3 0.4 0.9 7.8 9.7 7.3 11.5 7.6 7.5 10.3 7.0 8.9 9.5 DHX33 "DDX33, DKFZp762F2011, FLJ21972" ENSG00000005100 "DEAH-box helicase 33" Q9H6R0 17 5440912-5469060 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073875 Supported Supported Nucleoli Nucleoli "HPA073875: " "unprognostic (4.96e-2)" "unprognostic (1.35e-1)" "unprognostic (3.41e-2)" "unprognostic (2.51e-2)" "unprognostic (9.24e-2)" "unprognostic (1.90e-1)" "unprognostic (1.49e-2)" "unprognostic (6.15e-2)" "unprognostic (3.11e-2)" "unprognostic (3.80e-1)" "unprognostic (2.10e-1)" "prognostic unfavourable (6.10e-4)" "unprognostic (1.03e-1)" "unprognostic (4.66e-1)" "unprognostic (3.55e-1)" "unprognostic (4.69e-2)" "unprognostic (3.37e-2)" 10.0 10.4 11.6 11.0 14.6 7.0 12.9 15.8 22.0 9.0 8.7 14.1 8.6 8.6 12.4 7.9 11.2 11.2 9.2 7.7 9.7 7.0 8.2 13.4 8.0 10.1 11.0 13.2 11.1 12.1 16.5 7.3 11.5 10.3 10.0 10.7 11.3 10.4 10.8 13.9 12.5 8.7 11.1 8.0 11.1 9.6 10.1 11.7 8.4 9.5 9.4 10.3 9.6 9.5 3.7 3.4 2.6 3.5 3.0 2.5 0.7 10.3 15.3 9.8 17.5 4.1 8.4 12.2 10.2 6.4 15.8 12.8 9.6 4.5 25.3 7.2 8.4 12.3 19.9 16.0 20.2 8.1 19.1 10.0 12.5 16.2 8.2 13.4 9.1 7.0 9.8 16.8 23.1 11.7 13.3 12.6 8.6 7.3 13.5 7.3 21.7 7.8 18.2 14.4 13.7 7.2 8.0 8.6 12.4 10.7 9.2 15.8 7.2 7.0 10.8 10.9 11.5 8.6 21.6 4.7 5.0 13.0 7.8 16.0 15.6 0.6 3.5 1.8 2.2 1.4 2.1 2.5 2.5 1.4 1.4 3.7 2.5 2.4 2.6 3.0 1.3 3.4 1.8 0.7 11.6 14.6 15.8 22.0 9.7 7.0 11.0 13.2 10.3 11.7 DHX34 "DDX34, KIAA0134" ENSG00000134815 "DExH-box helicase 34" Q14147 19 47349281-47382704 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "neutrophil: 13.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 13.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042159, HPA043558" Uncertain Uncertain "Nucleoplasm,Intermediate filaments" "Nucleoplasm, Intermediate filaments" "HPA042159: AB_10963066, HPA043558: AB_10961262" "unprognostic (1.26e-1)" "unprognostic (5.17e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (1.08e-1)" "unprognostic (3.06e-3)" "prognostic unfavourable (8.63e-6)" "unprognostic (9.14e-2)" "unprognostic (4.74e-2)" "unprognostic (5.11e-2)" "unprognostic (4.76e-3)" "unprognostic (2.02e-2)" "prognostic unfavourable (3.16e-6)" "unprognostic (7.38e-2)" "unprognostic (1.59e-1)" "unprognostic (2.72e-1)" "unprognostic (7.21e-3)" 6.8 6.9 12.6 11.0 11.5 20.3 6.6 18.7 13.3 8.2 5.9 9.1 8.9 7.7 10.4 5.3 8.3 9.0 5.7 6.0 11.2 6.4 7.2 10.9 8.9 7.9 12.3 8.4 13.3 12.9 7.8 14.2 7.8 11.4 8.9 4.6 8.5 9.9 8.3 7.8 11.8 7.0 6.6 10.5 13.5 6.7 21.8 12.5 5.6 9.6 4.6 9.6 7.3 11.2 1.5 1.9 13.5 2.2 0.8 1.8 1.1 7.1 18.8 4.6 9.1 4.1 2.8 8.8 5.7 1.9 5.9 5.3 12.0 7.0 11.0 5.8 3.2 10.5 6.4 7.5 3.0 9.1 17.4 11.5 10.2 9.1 4.5 8.9 4.9 3.5 6.1 10.0 5.6 3.9 19.1 4.8 3.9 8.4 8.8 22.2 9.6 11.3 9.7 3.7 6.6 3.2 9.7 8.3 5.1 7.0 7.0 4.6 6.3 5.7 4.4 6.9 9.0 4.3 10.0 7.3 10.0 10.3 5.6 6.5 8.1 1.0 2.0 0.8 1.3 2.2 1.2 1.2 1.0 1.8 1.9 1.5 1.6 0.7 13.5 0.8 1.7 1.5 0.6 1.1 12.6 11.5 18.7 13.3 11.2 6.4 12.3 8.4 11.4 12.5 DHX35 "C20orf15, DDX35, FLJ22759, KAIA0875" ENSG00000101452 "DEAH-box helicase 35" Q9H5Z1 20 38962299-39039723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054451, HPA062700" Uncertain Approved "Nucleoplasm,Nuclear bodies,Centrosome" "Nuclear bodies" "Nucleoplasm, Centrosome" "HPA054451: , HPA062700: " "unprognostic (8.31e-2)" "unprognostic (2.34e-2)" "unprognostic (5.51e-2)" "prognostic unfavourable (4.25e-5)" "unprognostic (1.29e-2)" "unprognostic (8.38e-2)" "prognostic unfavourable (5.63e-6)" "unprognostic (9.83e-2)" "unprognostic (2.21e-1)" "unprognostic (6.22e-2)" "unprognostic (4.47e-2)" "unprognostic (5.67e-2)" "unprognostic (8.57e-2)" "unprognostic (1.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (3.31e-1)" 10.4 7.3 9.7 6.9 14.6 13.9 9.8 9.7 14.3 12.2 23.2 14.8 10.7 9.9 19.7 13.9 13.9 12.5 9.2 16.9 9.0 5.8 10.4 7.5 8.7 12.6 8.2 6.7 13.9 6.5 12.1 13.5 8.4 10.9 13.3 14.3 12.4 10.4 12.6 12.5 11.1 12.4 14.7 9.9 8.4 13.4 12.5 9.4 12.1 8.5 7.6 11.2 15.9 11.8 4.6 6.7 2.0 4.9 5.8 8.2 4.4 7.3 4.4 11.9 4.9 4.6 6.0 8.4 4.4 7.8 10.1 7.8 21.0 7.2 8.4 7.8 8.4 11.7 8.2 12.9 10.1 2.1 4.0 11.2 10.0 11.9 5.5 13.0 5.9 7.0 8.3 8.9 8.4 4.5 11.3 4.8 5.4 6.0 21.3 10.0 6.8 9.9 10.4 17.4 6.8 3.7 8.4 10.5 8.2 12.1 7.3 11.1 9.9 10.8 4.4 14.6 8.0 5.7 9.1 4.8 6.4 8.8 8.6 5.9 7.6 0.0 4.9 2.0 5.3 4.5 5.2 4.6 4.5 5.6 6.7 4.3 8.2 4.3 1.0 5.8 3.8 2.4 2.8 4.4 9.7 14.6 9.7 14.3 9.0 5.8 8.2 6.7 10.9 9.4 DHX36 "DDX36, KIAA1488, MLEL1" ENSG00000174953 "DEAH-box helicase 36" Q9H2U1 3 154272546-154324497 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Differentiation, Immunity, Innate immunity, Transcription, Transcription regulation, Translation regulation, Transport" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035399 Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA035399: AB_10670115" "unprognostic (8.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.86e-1)" "unprognostic (3.50e-3)" "unprognostic (2.67e-2)" "unprognostic (3.22e-1)" "unprognostic (8.80e-3)" "unprognostic (1.03e-1)" "unprognostic (7.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.94e-2)" "unprognostic (3.90e-2)" "unprognostic (2.72e-1)" "unprognostic (5.09e-2)" "unprognostic (5.27e-1)" "unprognostic (4.96e-2)" "unprognostic (1.37e-1)" 16.3 14.0 11.5 14.1 27.5 12.6 15.7 19.0 21.3 17.9 14.7 10.3 12.4 10.7 20.4 10.6 14.5 14.3 13.7 23.9 13.4 12.7 16.7 17.1 14.6 17.0 12.2 15.0 20.0 13.7 34.0 36.2 16.4 20.1 15.7 12.2 9.3 15.5 20.5 53.4 14.7 14.3 15.1 13.7 18.9 13.4 28.3 11.3 24.3 20.4 13.4 17.1 20.7 15.6 6.3 5.9 3.1 5.7 4.8 6.9 1.1 26.7 18.3 24.9 14.3 11.7 16.5 12.4 17.5 17.6 20.0 23.9 18.6 21.5 26.0 28.4 15.3 17.3 23.4 14.8 31.5 24.9 15.5 18.8 15.7 10.5 19.9 26.1 16.5 18.6 12.6 21.4 26.3 17.1 17.7 15.0 18.4 13.0 21.6 5.7 33.0 17.6 22.5 20.9 37.4 14.3 19.0 23.3 24.8 18.2 19.4 25.4 19.9 13.3 19.3 21.0 13.2 19.6 34.9 28.1 18.1 37.5 17.0 13.7 22.2 1.9 2.7 3.1 6.9 2.8 4.4 4.7 6.1 4.7 2.3 6.3 5.8 6.0 1.1 4.8 5.7 5.9 5.4 1.1 11.5 27.5 19.0 21.3 13.4 12.7 12.2 15.0 20.1 11.3 DHX37 "DDX37, Dhr1, KIAA1517, MGC2695, MGC4322" ENSG00000150990 "DEAH-box helicase 37" Q8IY37 12 124946825-124989122 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047607 Approved Approved "Nuclear membrane" "Nuclear membrane" "HPA047607: " "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.32e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "prognostic unfavourable (9.54e-10)" "unprognostic (2.38e-2)" "unprognostic (5.14e-2)" "unprognostic (2.90e-2)" "unprognostic (2.07e-1)" "unprognostic (3.16e-2)" "unprognostic (8.28e-3)" "unprognostic (1.40e-2)" "unprognostic (2.27e-1)" "unprognostic (2.85e-2)" "unprognostic (2.73e-1)" 9.5 9.2 8.6 12.7 12.1 29.6 9.3 5.7 12.1 8.9 7.9 11.8 6.0 10.2 11.6 6.5 11.2 9.8 10.7 12.4 7.3 5.4 7.4 10.7 8.2 13.3 11.6 7.4 12.7 14.4 4.7 5.7 6.7 10.5 8.7 5.7 5.6 9.1 7.3 22.7 15.8 9.5 7.7 7.5 12.2 9.1 6.8 11.1 7.8 8.9 9.7 11.5 9.7 13.6 4.3 1.6 0.2 2.5 1.4 2.5 1.4 7.4 21.3 3.7 11.6 3.8 4.3 9.6 2.6 3.8 8.5 6.9 26.7 5.1 18.1 9.9 3.1 10.3 9.8 5.7 3.1 15.7 18.2 8.9 12.0 10.6 5.3 11.7 16.1 3.9 6.5 14.7 2.4 4.9 18.7 5.1 5.0 10.9 16.5 12.3 13.7 12.9 12.2 3.7 8.9 3.7 16.8 6.6 3.3 7.0 7.5 5.6 8.4 10.4 5.8 9.9 7.4 14.1 17.1 11.6 14.5 17.9 6.5 6.9 12.4 0.0 0.6 0.0 1.5 2.0 2.2 4.3 1.8 2.5 1.6 0.2 0.9 0.8 0.2 1.4 2.5 1.2 0.9 1.4 8.6 12.1 5.7 12.1 7.3 5.4 11.6 7.4 10.5 11.1 DHX38 "DDX38, hPrp16, KIAA0224, PRP16, PRPF16" ENSG00000140829 "DEAH-box helicase 38" Q92620 16 72093562-72112912 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041347, HPA041604" Uncertain Supported Nucleoplasm Nucleoplasm "HPA041347: AB_10796571, HPA041604: " "unprognostic (2.38e-1)" "unprognostic (1.89e-1)" "unprognostic (1.24e-2)" "unprognostic (3.25e-2)" "unprognostic (1.07e-1)" "unprognostic (1.01e-1)" "unprognostic (6.32e-3)" "unprognostic (8.50e-3)" "unprognostic (6.97e-2)" "unprognostic (1.45e-1)" "unprognostic (7.92e-2)" "unprognostic (1.28e-3)" "unprognostic (4.20e-3)" "unprognostic (2.68e-1)" "unprognostic (9.46e-2)" "unprognostic (2.40e-1)" "unprognostic (2.40e-2)" 21.8 16.5 21.1 22.2 25.0 35.1 20.5 36.0 29.4 18.6 19.5 23.5 19.4 20.1 24.1 13.5 21.1 19.9 18.1 19.2 24.1 13.7 17.3 20.8 20.6 26.1 24.1 20.7 29.0 17.3 36.6 18.7 19.3 20.9 18.3 17.2 17.9 20.4 16.4 33.0 27.2 23.0 23.5 22.5 27.3 19.4 17.5 27.8 24.6 20.8 23.2 23.1 20.5 21.4 10.4 8.1 8.3 10.6 11.8 14.9 6.3 14.4 21.5 15.7 8.7 13.7 10.6 20.6 13.1 12.8 19.6 15.1 26.1 14.5 19.3 11.8 19.7 19.1 18.1 18.0 15.2 9.6 19.5 14.8 18.3 35.5 12.7 17.4 26.9 14.7 16.6 26.4 19.1 16.9 21.9 9.2 12.0 44.6 16.6 19.7 19.7 12.4 21.5 10.8 19.1 9.4 13.8 14.1 15.5 16.8 8.0 9.3 14.6 14.5 19.1 18.9 16.8 13.7 14.3 22.7 17.9 37.1 17.8 12.1 14.7 7.4 7.9 8.3 14.9 10.6 13.7 10.4 9.3 10.7 8.1 8.2 10.4 10.8 8.2 11.8 6.6 7.4 10.9 6.3 21.1 25.0 36.0 29.4 24.1 13.7 24.1 20.7 20.9 27.8 DHX40 "ARG147, DDX40, FLJ22060, PAD" ENSG00000108406 "DEAH-box helicase 40" Q8IX18 17 59565525-59608345 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044350 Uncertain Supported Nucleoplasm Nucleoplasm "HPA044350: AB_10960560" "unprognostic (1.58e-2)" "unprognostic (3.10e-1)" "prognostic favourable (4.05e-5)" "unprognostic (4.09e-2)" "unprognostic (5.23e-2)" "unprognostic (2.84e-1)" "unprognostic (4.57e-3)" "unprognostic (7.53e-3)" "unprognostic (2.86e-2)" "unprognostic (1.80e-1)" "unprognostic (7.23e-2)" "unprognostic (3.08e-1)" "unprognostic (9.48e-3)" "unprognostic (2.22e-1)" "unprognostic (1.25e-2)" "unprognostic (1.11e-1)" "unprognostic (3.10e-1)" 22.4 24.2 16.2 14.0 18.1 19.5 24.8 21.7 18.4 21.4 16.5 17.5 23.7 12.8 27.0 25.0 19.3 24.8 16.5 19.8 17.1 19.5 29.5 13.1 16.7 16.8 17.9 14.7 29.7 21.0 51.3 45.8 21.9 19.0 21.6 15.4 13.7 19.3 27.8 20.4 21.3 12.3 18.9 19.9 15.6 17.2 28.4 16.8 26.1 28.2 16.0 15.5 26.0 19.7 5.4 6.9 18.8 6.6 4.2 10.6 6.1 11.5 21.3 27.1 17.6 16.6 17.2 14.9 10.5 20.1 16.1 18.2 8.3 11.6 15.2 29.5 15.0 8.6 19.3 14.8 25.0 12.0 28.2 13.9 16.0 9.2 13.0 16.7 6.5 13.1 13.7 13.6 13.2 17.1 11.6 14.1 10.9 21.0 20.5 10.3 10.3 15.6 19.7 19.0 16.6 16.1 9.3 19.3 47.5 18.9 7.5 19.2 24.4 9.8 13.9 19.4 24.2 6.9 10.2 17.4 19.1 9.8 22.8 11.7 13.2 8.5 6.6 10.5 8.1 6.5 10.6 5.1 5.9 5.8 6.9 5.4 5.9 6.9 18.8 4.2 4.4 3.5 6.0 6.1 16.2 18.1 21.7 18.4 17.1 19.5 17.9 14.7 19.0 16.8 DHX57 DDX57 ENSG00000163214 "DExH-box helicase 57" Q6P158 2 38797729-38875934 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036160 Uncertain Approved "Nucleoli,Intermediate filaments,Microtubules,Cytosol" "Intermediate filaments, Microtubules" "Nucleoli, Cytosol" "HPA036160: AB_10670711" "unprognostic (6.78e-2)" "unprognostic (3.08e-1)" "unprognostic (3.49e-2)" "unprognostic (2.03e-3)" "unprognostic (3.25e-2)" "unprognostic (3.43e-1)" "prognostic unfavourable (3.32e-6)" "unprognostic (1.75e-2)" "unprognostic (2.74e-1)" "unprognostic (1.45e-1)" "unprognostic (7.35e-2)" "unprognostic (1.82e-2)" "unprognostic (2.55e-2)" "unprognostic (1.47e-1)" "unprognostic (3.88e-2)" "unprognostic (7.03e-3)" "unprognostic (1.77e-1)" 9.6 11.2 9.7 8.5 16.7 7.0 10.4 11.9 16.4 14.1 9.4 9.9 9.8 4.2 13.9 17.1 8.4 11.2 9.5 9.3 9.6 11.0 11.2 7.2 7.9 9.2 8.9 9.5 13.2 9.5 18.9 17.9 11.2 13.1 10.5 9.2 11.6 7.8 14.2 11.5 11.1 6.9 11.8 7.7 9.9 7.9 27.7 8.3 13.9 11.8 8.1 11.1 10.5 8.3 7.1 5.2 1.7 10.1 3.3 6.0 4.2 16.9 13.6 15.2 11.4 10.0 12.4 12.5 11.8 11.6 11.2 11.0 10.9 5.2 4.9 11.9 12.0 8.8 17.2 13.0 18.4 20.4 12.7 9.6 9.1 14.8 9.1 10.1 5.6 11.8 7.9 14.5 9.1 14.9 12.3 7.0 12.1 12.3 10.1 9.3 19.0 8.1 5.0 20.2 9.7 10.3 6.5 12.6 18.5 11.8 12.2 13.8 8.5 5.6 11.4 11.1 12.9 8.5 12.6 7.4 8.2 2.1 8.7 7.1 7.4 1.7 10.1 1.7 4.5 6.9 6.0 5.7 4.0 3.5 5.2 7.1 4.8 3.0 0.5 3.3 8.0 1.7 3.3 4.2 9.7 16.7 11.9 16.4 9.6 11.0 8.9 9.5 13.1 8.3 DHX58 "D11LGP2, LGP2" ENSG00000108771 "DExH-box helicase 58" Q96C10 17 42101404-42112733 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 24.4;BJ hTERT+ SV40 Large T+ RasG12V: 28.5;SK-MEL-30: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018670, HPA019570" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" Nucleoplasm "HPA018670: AB_1847665, HPA019570: AB_1847666" "prognostic favourable (3.45e-4)" "unprognostic (1.03e-2)" "unprognostic (3.56e-3)" "unprognostic (1.54e-2)" "unprognostic (2.45e-2)" "unprognostic (4.82e-2)" "unprognostic (2.05e-3)" "unprognostic (5.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.15e-1)" "unprognostic (6.02e-2)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (8.65e-2)" "unprognostic (8.01e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" 12.7 16.3 6.7 15.3 7.8 11.1 9.8 2.8 8.4 7.9 9.8 9.6 15.0 8.2 9.6 16.2 8.7 12.0 12.6 5.3 6.5 5.3 11.0 20.9 21.7 14.4 5.9 9.0 12.9 7.4 4.3 9.6 7.0 8.2 10.6 5.0 13.4 18.0 17.1 6.9 7.8 10.5 9.2 7.9 17.1 9.1 10.7 5.1 17.2 7.5 5.6 12.9 10.9 7.6 6.4 7.6 8.6 12.0 7.6 7.1 5.9 1.2 0.0 0.0 0.7 6.2 5.3 0.2 1.7 11.8 24.4 28.5 0.1 7.6 0.1 1.8 2.8 1.0 0.1 1.9 0.9 4.7 0.1 2.0 1.1 0.4 6.9 1.8 4.6 8.6 3.2 2.1 2.1 2.9 0.0 6.7 1.3 0.0 10.9 2.2 0.2 0.0 3.9 0.0 0.5 2.7 4.4 0.2 0.0 0.7 3.1 13.9 4.2 1.9 1.2 1.2 0.0 0.4 0.6 2.3 1.9 0.1 2.4 1.7 1.3 3.1 9.9 8.6 4.5 12.0 6.5 6.4 6.4 4.0 7.6 4.9 7.1 5.3 4.0 7.6 10.5 2.5 5.5 5.9 6.7 7.8 2.8 8.4 6.5 5.3 5.9 9.0 8.2 5.1 DHX8 "DDX8, Dhr2, HRH1, PRP22, PRPF22" ENSG00000067596 "DEAH-box helicase 8" Q14562 17 43483865-43544463 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049285 Approved Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Nucleoplasm "Nuclear bodies" "HPA049285: " "unprognostic (2.99e-1)" "unprognostic (4.42e-2)" "unprognostic (5.64e-2)" "unprognostic (9.02e-2)" "unprognostic (1.25e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-3)" "unprognostic (9.43e-2)" "unprognostic (2.58e-1)" "unprognostic (3.40e-2)" "unprognostic (2.26e-2)" "unprognostic (2.47e-1)" "unprognostic (1.50e-1)" "unprognostic (4.04e-1)" "unprognostic (5.08e-3)" "unprognostic (2.60e-1)" "unprognostic (6.28e-2)" 21.9 18.6 17.5 17.0 22.9 47.8 22.3 21.6 29.8 20.3 21.0 25.3 17.2 17.1 26.1 28.4 26.6 17.9 16.7 18.5 18.1 18.7 18.5 20.1 19.8 21.0 20.8 19.7 19.5 17.4 35.4 23.0 21.7 22.7 22.1 24.6 20.1 21.7 21.7 25.2 32.9 22.0 24.6 19.2 27.3 19.5 34.6 20.6 40.8 20.5 17.8 28.9 19.4 22.6 11.5 16.3 23.3 20.4 9.5 14.9 9.8 12.3 35.1 19.1 23.7 19.0 19.5 10.6 13.0 27.5 28.8 27.7 16.0 12.6 17.1 12.1 25.5 16.8 28.6 22.9 33.8 17.9 22.6 14.5 26.8 24.7 16.3 25.1 22.0 9.7 19.4 23.6 26.0 25.4 16.1 16.9 22.2 13.4 31.8 22.4 15.5 13.4 19.4 36.4 17.6 19.5 25.9 16.5 24.9 14.6 8.4 11.7 19.5 24.8 17.3 22.4 12.2 16.1 19.4 12.7 15.1 19.4 18.6 15.7 17.9 23.3 15.2 17.2 13.7 20.4 13.6 11.5 11.4 14.9 16.3 10.6 11.2 10.9 19.2 9.5 19.6 8.4 11.7 9.8 17.5 22.9 21.6 29.8 18.1 18.7 20.8 19.7 22.7 20.6 DHX9 "DDX9, LKP, RHA" ENSG00000135829 "DExH-box helicase 9" Q08211 1 182839369-182887751 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, DNA replication, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, mRNA processing, mRNA splicing, mRNA transport, RNA-mediated gene silencing, Transcription, Transcription regulation, Transcription termination, Translation regulation, Transport" "Activator, DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011819, HPA028050" Supported Supported Nucleoplasm 97000 Nucleoplasm "CAB011819: AB_777725, HPA028050: AB_10603564" "unprognostic (8.14e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-2)" "unprognostic (4.80e-2)" "unprognostic (1.58e-1)" "unprognostic (7.40e-2)" "prognostic unfavourable (3.17e-4)" "unprognostic (9.98e-2)" "prognostic unfavourable (6.04e-4)" "unprognostic (2.76e-1)" "unprognostic (2.88e-2)" "unprognostic (5.53e-2)" "unprognostic (7.51e-2)" "unprognostic (1.43e-1)" "unprognostic (1.70e-1)" "unprognostic (3.17e-1)" "unprognostic (1.99e-1)" 30.2 25.9 25.7 28.5 28.6 68.9 32.9 42.5 33.1 31.9 24.5 23.3 25.2 19.8 38.2 24.2 27.7 30.6 19.7 22.9 24.4 22.6 36.2 31.4 27.8 32.0 34.2 23.1 37.5 24.9 51.8 35.8 28.5 28.0 25.7 30.1 21.1 28.2 29.4 27.6 26.6 27.0 31.6 25.3 32.8 26.5 29.4 37.4 68.3 30.1 31.6 41.2 32.4 31.9 16.8 22.9 12.0 17.4 14.7 21.9 15.0 35.1 34.5 49.5 27.2 25.9 20.1 48.9 31.2 28.6 45.4 30.8 38.5 27.2 56.5 30.5 28.0 30.5 75.1 33.8 50.8 22.9 37.3 37.6 28.2 26.0 14.6 54.4 25.8 17.9 17.0 44.5 12.1 35.4 59.0 20.3 36.3 30.9 55.0 13.4 62.7 21.3 50.2 46.2 32.3 29.3 40.9 35.7 41.0 44.2 28.0 18.2 32.7 30.8 27.6 28.2 31.5 28.6 42.2 21.3 34.8 67.1 17.7 29.9 38.2 5.6 16.0 12.0 19.2 17.4 21.9 16.8 16.8 17.6 22.9 14.6 18.4 19.9 6.5 14.7 14.3 11.1 15.4 15.0 25.7 28.6 42.5 33.1 24.4 22.6 34.2 23.1 28.0 37.4 DICER1 "Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1" ENSG00000100697 "Dicer 1, ribonuclease III" Q9UPY3 14 95086228-95158010 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing" "Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000694, CAB068185" Approved Supported Cytosol Cytosol "CAB068185: , HPA000694: AB_1078661" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" "unprognostic (6.75e-2)" "unprognostic (9.62e-2)" "unprognostic (1.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.21e-1)" "unprognostic (8.52e-3)" "unprognostic (5.73e-2)" "unprognostic (9.22e-2)" "unprognostic (4.22e-2)" "unprognostic (9.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.04e-3)" "unprognostic (3.74e-2)" 23.2 12.5 18.4 22.4 33.3 20.5 23.2 28.5 29.9 19.0 18.1 31.4 22.4 13.0 20.8 20.6 23.4 18.5 16.2 15.3 22.0 14.1 19.5 23.6 22.4 20.3 29.7 19.6 23.8 19.8 26.9 30.9 29.9 23.2 20.3 19.7 14.5 19.5 18.9 28.0 20.7 17.3 19.0 26.8 20.7 17.1 20.6 32.0 17.0 23.8 14.7 20.3 20.7 24.1 2.5 1.8 10.7 7.2 1.2 3.3 1.0 12.8 13.4 25.1 9.3 6.5 9.8 19.9 10.6 6.4 6.8 8.2 17.0 9.9 14.5 11.5 9.8 15.2 19.9 10.0 14.2 22.5 8.9 21.9 7.4 12.2 6.6 13.4 13.5 9.1 8.3 9.1 13.9 10.1 9.2 12.9 11.4 18.0 15.0 8.9 7.1 6.6 12.0 20.5 8.0 9.0 20.5 20.8 11.8 10.7 11.0 12.0 12.4 9.9 10.0 5.2 10.3 10.1 11.9 14.8 21.1 20.6 5.4 10.9 9.3 3.1 3.0 1.2 1.6 3.1 3.3 1.9 1.5 1.2 1.8 2.5 1.5 1.3 10.7 1.2 7.2 1.6 1.6 1.0 18.4 33.3 28.5 29.9 22.0 14.1 29.7 19.6 23.2 32.0 DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease mutation, Dwarfism, Mental retardation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 49.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "NK-cell: 5.5" "Lineage enriched" "Detected in single" 6 "NK-cells: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037487, HPA057526" Approved Supported Mitochondria Mitochondria "HPA037487: AB_10672493, HPA057526: " "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" 1.6 1.2 2.0 13.7 2.4 7.0 3.0 6.2 3.8 1.6 4.5 1.1 0.8 3.5 3.0 1.8 3.2 1.0 2.4 2.0 2.5 2.2 3.4 6.2 3.3 8.4 2.9 5.0 1.9 2.4 1.1 2.3 4.0 1.7 3.0 5.0 0.9 2.3 0.8 2.3 2.9 5.2 1.9 3.0 5.2 2.6 7.0 1.4 49.1 1.5 5.1 10.8 2.3 2.0 0.4 0.1 0.9 0.1 5.5 0.6 0.1 13.7 7.1 16.3 11.5 1.8 1.3 11.5 6.8 5.7 9.8 12.1 17.0 9.0 14.1 2.6 2.1 8.5 9.3 3.6 11.8 8.7 7.0 8.6 4.4 6.5 0.5 14.7 9.3 1.0 1.4 7.0 2.0 4.4 12.5 12.8 5.6 4.8 22.7 10.7 11.5 13.4 17.8 11.3 4.5 4.2 6.4 7.4 8.9 9.4 11.9 2.2 9.2 6.3 1.8 3.8 11.7 4.8 12.9 6.5 7.3 21.1 3.2 14.1 4.9 0.0 0.0 0.9 0.2 0.0 0.2 0.4 0.2 0.6 0.1 0.4 0.3 0.3 0.1 5.5 0.1 0.0 0.4 0.1 2.0 2.4 6.2 3.8 2.5 2.2 2.9 5.0 1.7 1.4 DNAJC6 "KIAA0473, PARK19" ENSG00000116675 "DnaJ heat shock protein family (Hsp40) member C6" O75061 1 65248219-65415869 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chaperone, Hydrolase, Protein phosphatase" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 91.4" "Cell line enhanced" "Detected in many" "HDLM-2: 20.9;HEL: 55.8;K-562: 21.7" "Cancer enhanced" "Detected in many" "glioma: 5.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "gdT-cell: 1.5" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031182, HPA054917" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" Cytosol "Nucleoplasm, Plasma membrane" "HPA031182: AB_10611957, HPA054917: " "unprognostic (6.99e-2)" "unprognostic (2.00e-3)" "unprognostic (3.19e-1)" "unprognostic (7.94e-7)" "unprognostic (1.59e-1)" "unprognostic (7.61e-3)" "unprognostic (1.87e-4)" "unprognostic (2.98e-1)" "unprognostic (1.89e-1)" "unprognostic (4.14e-1)" "unprognostic (4.22e-3)" "unprognostic (1.53e-1)" "prognostic favourable (2.81e-4)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-1)" "unprognostic (8.67e-3)" 2.1 12.1 18.6 2.2 28.5 5.0 2.0 24.2 91.4 2.2 2.8 26.9 0.0 2.3 1.9 1.8 1.7 2.4 2.3 9.0 25.0 26.7 8.5 1.6 2.7 1.6 28.8 23.8 1.9 3.4 2.1 7.5 8.0 40.5 2.5 3.0 2.2 1.7 2.1 1.6 2.1 2.3 2.2 28.7 3.2 2.9 3.2 21.1 0.0 3.0 0.0 1.7 1.8 0.6 0.5 0.5 0.0 0.0 0.6 1.5 0.3 3.5 0.9 0.0 1.6 0.7 0.2 8.3 7.0 11.4 11.5 11.3 0.9 0.1 3.3 0.6 2.9 0.8 5.0 1.1 9.1 20.9 2.4 55.8 1.9 0.2 0.0 1.8 1.4 1.0 0.8 1.1 4.9 0.2 21.7 0.4 2.3 0.6 0.7 0.0 2.3 0.7 0.0 1.7 0.1 8.7 0.0 13.9 9.6 4.1 5.5 1.9 2.6 0.1 2.1 1.7 1.2 0.2 2.0 2.1 1.3 1.0 4.7 1.4 2.8 0.0 0.0 0.0 1.5 0.0 0.1 0.5 0.5 0.9 0.0 0.0 0.4 0.6 0.0 0.6 0.0 0.5 0.0 0.3 18.6 28.5 24.2 37.4 25.0 26.7 28.8 23.8 40.5 21.1 DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 26.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted in other tissues" 160000 Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favourable (1.14e-4)" 1.5 1.4 1.5 2.6 1.6 1.7 1.5 3.8 2.5 2.2 12.2 1.8 1.5 14.9 1.5 2.2 3.4 1.2 2.5 1.5 1.5 1.2 11.4 1.5 1.5 4.4 1.5 1.5 2.0 13.7 1.6 12.2 1.9 3.1 5.1 2.1 1.5 3.3 1.5 1.5 3.9 26.7 1.5 1.5 2.3 6.0 2.7 1.5 1.5 1.6 2.6 3.8 1.9 2.3 4.5 2.2 9.2 2.0 1.9 3.4 1.0 2.4 5.7 10.0 5.2 2.9 2.5 4.8 4.0 0.7 3.2 4.7 6.8 6.0 10.5 3.2 0.6 4.2 3.6 1.1 3.5 4.6 5.5 3.7 8.5 4.5 1.5 2.6 8.5 2.0 4.2 4.3 1.0 2.1 9.2 4.7 2.7 10.2 5.2 11.3 6.1 3.1 12.4 4.6 5.1 2.7 2.1 7.1 6.6 2.9 9.1 1.6 9.0 6.5 2.9 6.0 4.5 3.8 2.2 4.2 6.0 18.2 1.7 4.8 5.8 4.3 2.0 5.3 3.0 1.3 1.9 2.5 2.3 2.4 1.0 4.5 2.7 3.4 9.2 1.9 1.2 2.2 2.4 1.0 1.5 1.6 3.8 2.5 1.5 1.2 1.5 1.5 3.1 1.5 DNASE2 "DNL, DNL2" ENSG00000105612 "Deoxyribonuclease 2, lysosomal" O00115 19 12875211-12881468 "Enzymes, Predicted intracellular proteins" Apoptosis "Developmental protein, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066185 Enhanced "Intracellular and membrane" 720000 "HPA066185: " "unprognostic (9.62e-2)" "unprognostic (2.19e-3)" "unprognostic (8.97e-2)" "unprognostic (7.45e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (5.42e-2)" "unprognostic (4.85e-2)" "unprognostic (1.40e-1)" "unprognostic (5.12e-2)" "unprognostic (4.37e-2)" "unprognostic (2.58e-2)" "unprognostic (4.69e-2)" "unprognostic (3.57e-1)" "unprognostic (1.98e-1)" 18.7 22.1 13.1 17.0 13.4 4.8 16.9 6.0 12.9 21.2 22.8 15.9 15.8 14.6 19.6 27.9 22.7 17.0 20.6 18.0 11.5 9.4 17.1 40.7 37.4 34.5 14.9 7.7 20.0 33.3 21.2 18.9 28.1 11.6 18.4 13.5 22.6 24.9 18.0 16.6 20.5 15.9 14.6 13.1 24.1 20.9 9.4 11.0 20.0 36.4 13.6 26.9 20.5 14.8 11.8 10.3 20.1 37.8 21.9 26.6 19.6 16.3 8.3 0.7 22.4 24.7 12.9 14.7 8.4 23.3 8.6 21.9 0.7 11.7 7.8 24.4 15.1 19.2 8.7 8.8 4.8 21.6 9.7 3.5 9.9 4.2 19.9 7.0 32.5 12.6 20.9 6.8 10.6 12.9 3.1 32.4 5.7 21.3 6.8 3.8 1.4 14.9 4.4 3.9 17.2 9.4 6.9 4.8 7.3 12.7 18.4 31.2 27.2 6.5 7.7 17.9 5.7 17.8 7.7 35.5 36.3 9.7 29.8 6.5 9.1 20.1 25.5 3.6 22.3 33.8 18.4 11.6 19.6 23.6 5.0 11.8 17.6 19.2 14.8 21.9 37.8 10.3 26.6 19.6 13.1 13.4 6.0 12.9 11.5 9.4 14.9 7.7 11.6 11.0 DNASE2B DLAD ENSG00000137976 "Deoxyribonuclease 2 beta" Q8WZ79 1 84398532-84415018 "Enzymes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "salivary gland: 98.7" "Cell line enhanced" "Detected in some" "AN3-CA: 1.5;HL-60: 1.0;HUVEC TERT2: 2.1;SK-MEL-30: 2.5;U-266/70: 1.2" "Cancer enhanced" "Detected in some" "prostate cancer: 9.3" "Region enhanced" "Detected in single" "basal ganglia: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" "unprognostic (2.24e-1)" "unprognostic (3.57e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (4.70e-2)" "unprognostic (3.70e-1)" "unprognostic (2.86e-1)" "unprognostic (1.62e-2)" "unprognostic (9.87e-2)" "unprognostic (7.90e-2)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (3.82e-5)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" "unprognostic (6.79e-2)" "unprognostic (3.08e-3)" 16.2 0.1 0.2 0.1 2.2 0.1 0.3 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.6 0.1 0.2 13.0 1.2 0.3 0.0 0.3 0.4 0.0 0.4 0.1 0.2 2.9 0.3 0.0 98.7 0.1 1.8 0.0 0.1 0.1 1.7 0.5 0.6 0.3 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.5 0.0 0.0 0.0 0.0 0.2 0.4 0.0 1.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.2 0.0 0.3 0.3 0.6 0.3 0.0 0.2 0.0 DNM1 DNM ENSG00000106976 "Dynamin 1" Q05193 9 128191655-128255248 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 133.5" "Cell line enhanced" "Detected in many" "A549: 48.8;U-87 MG: 18.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005920, HPA049910, HPA061801" Enhanced Supported Nucleoplasm 440000 Nucleoplasm "CAB005920: , HPA049910: , HPA061801: " "unprognostic (3.25e-2)" "unprognostic (5.49e-2)" "unprognostic (1.34e-3)" "unprognostic (3.95e-2)" "unprognostic (4.57e-2)" "unprognostic (1.16e-1)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (5.53e-2)" "unprognostic (6.53e-2)" "unprognostic (6.62e-3)" "unprognostic (6.30e-1)" "unprognostic (9.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (3.07e-3)" "unprognostic (1.10e-3)" 5.9 6.1 31.5 3.3 36.9 2.3 4.6 57.7 133.5 11.7 3.0 2.5 0.0 2.4 4.6 2.7 3.3 6.3 9.0 2.7 33.4 24.0 2.9 1.8 2.5 2.5 18.3 33.0 1.6 4.7 3.2 5.5 2.7 33.0 2.9 2.9 4.3 2.6 3.1 2.3 4.6 3.3 4.4 5.1 1.6 2.6 4.0 1.8 0.0 1.9 0.4 2.3 3.6 3.7 0.3 0.4 0.5 0.3 0.0 0.3 0.7 3.2 48.8 4.4 1.0 1.4 14.9 0.2 3.0 7.3 6.2 2.6 0.6 1.0 0.0 4.2 6.3 5.8 0.7 0.3 3.4 0.0 4.7 3.1 7.0 0.2 1.0 0.4 2.2 3.9 0.1 4.8 0.0 0.0 1.1 0.2 0.0 1.3 0.2 1.0 4.7 8.9 5.8 0.1 1.5 0.9 0.0 6.3 10.6 10.4 0.3 0.4 0.1 4.2 0.2 0.2 14.1 14.2 6.2 0.4 0.1 0.3 18.6 0.1 1.0 0.0 0.3 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.4 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.7 31.5 36.9 57.7 71.8 33.4 24.0 18.3 33.0 33.0 1.8 DNM1L "DRP1, DVLP, DYMPLE, HDYNIV, VPS1" ENSG00000087470 "Dynamin 1 like" O00429 12 32679200-32745650 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Endocytosis, Necrosis" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009952, HPA039324" Supported Enhanced Vesicles,Cytosol 10000000 Cytosol Vesicles "CAB009952: AB_2093533, HPA039324: " "unprognostic (2.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (5.09e-1)" "unprognostic (4.06e-2)" "prognostic unfavourable (6.27e-6)" "unprognostic (8.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.04e-2)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (7.48e-2)" "unprognostic (1.57e-2)" 15.4 16.2 24.9 14.8 34.4 22.3 14.3 40.5 37.8 13.0 14.5 12.4 14.9 12.3 16.5 16.5 19.8 13.3 11.9 25.4 26.1 28.1 19.4 12.8 11.2 13.8 23.4 23.2 14.1 9.8 28.7 18.8 16.0 27.9 19.3 16.0 12.1 11.1 21.1 25.6 11.8 11.0 21.7 21.7 11.6 12.2 23.1 14.9 13.4 15.2 17.4 15.8 16.9 12.2 5.9 17.0 5.0 14.6 7.2 7.9 7.1 22.1 22.1 23.2 23.8 18.8 19.3 44.9 24.9 19.2 23.5 21.8 31.0 17.0 29.8 17.5 22.5 19.9 24.4 28.6 28.3 15.7 19.9 33.9 21.3 17.0 15.5 24.0 17.9 17.4 14.5 24.9 25.7 28.4 24.5 12.9 26.9 8.6 9.6 20.2 48.9 10.8 16.2 43.7 20.3 19.8 30.5 20.3 20.8 26.5 18.2 19.4 20.9 16.4 25.6 20.1 20.2 47.1 23.1 9.1 24.6 31.1 19.5 16.1 15.2 5.0 9.7 3.1 5.6 14.6 6.8 5.9 6.0 5.9 17.0 5.2 7.3 7.9 1.7 7.2 13.6 5.4 6.1 7.1 24.9 34.4 40.5 37.8 26.1 28.1 23.4 23.2 27.9 14.9 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" 500000 "Golgi apparatus, Cytosol" "HPA054246: " "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favourable (8.91e-4)" "prognostic unfavourable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 23.8 32.6 18.5 29.3 31.2 53.4 20.4 25.7 29.7 20.1 51.4 57.5 46.0 32.1 20.4 16.8 29.9 19.7 27.0 35.0 20.8 18.0 38.5 25.1 39.2 28.2 48.3 18.0 17.9 32.2 19.5 20.0 32.3 32.2 24.0 42.5 24.5 24.7 37.7 46.6 40.6 50.8 18.6 43.1 37.6 48.2 23.3 36.4 39.1 23.5 21.1 41.5 35.7 31.5 3.4 11.1 8.6 9.8 10.1 5.8 4.6 34.9 28.9 21.2 16.9 21.9 21.5 27.2 23.4 22.2 34.7 29.5 28.8 23.1 25.4 42.2 25.2 30.7 28.9 25.4 29.1 31.1 23.0 48.7 25.8 32.2 27.0 26.7 46.3 22.0 19.6 26.5 25.0 33.7 39.1 43.7 21.3 42.3 37.2 25.5 24.1 35.0 37.8 23.0 28.6 22.8 52.7 30.6 20.0 26.7 22.9 16.7 18.4 31.8 30.5 38.1 12.9 53.5 30.9 36.2 36.9 23.4 28.5 40.9 18.8 3.0 4.5 8.6 5.6 8.2 5.1 3.4 4.2 5.8 5.3 3.1 2.4 4.1 8.5 10.1 9.8 11.1 4.8 4.6 18.5 31.2 25.7 29.7 20.8 18.0 48.3 18.0 32.2 36.4 DNM3 KIAA0820 ENSG00000197959 "Dynamin 3" Q9UQ16 1 171841498-172418466 "Enzymes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.3" "Cell line enhanced" "Detected in many" "HEL: 17.9;HMC-1: 8.3;RH-30: 8.1;RPTEC TERT1: 15.5;U-251 MG: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 4.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064121 Approved "Golgi apparatus" "Golgi apparatus" "HPA064121: " "unprognostic (8.21e-2)" "unprognostic (6.80e-3)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (8.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.52e-3)" "unprognostic (6.46e-2)" "unprognostic (5.52e-2)" "unprognostic (2.96e-2)" "unprognostic (2.45e-2)" "unprognostic (3.37e-1)" "unprognostic (6.10e-4)" "unprognostic (1.60e-3)" "unprognostic (1.35e-1)" "unprognostic (2.22e-1)" "unprognostic (2.70e-3)" 5.0 19.3 14.1 2.3 28.3 2.6 3.4 41.4 39.7 6.8 2.7 26.8 0.0 1.9 5.9 3.1 3.0 6.0 5.1 3.0 14.3 16.3 5.8 1.4 7.5 2.5 19.6 17.7 4.6 2.6 3.5 10.3 1.6 47.3 3.6 2.7 2.9 3.7 3.6 2.5 4.0 2.4 5.7 16.4 3.6 5.3 5.4 22.1 0.0 3.4 0.0 2.2 4.3 3.6 0.7 0.7 1.1 0.4 1.0 4.0 3.8 0.6 2.0 1.6 0.3 1.2 0.8 0.0 0.4 1.0 0.8 1.0 0.0 2.9 0.0 6.2 0.9 0.2 1.2 2.3 0.7 0.8 2.3 17.9 3.0 0.0 0.1 0.3 8.3 0.6 0.4 0.9 0.5 0.4 0.0 0.2 0.3 0.0 1.1 0.1 4.7 1.4 1.1 8.1 0.0 15.5 0.1 3.2 0.6 2.1 0.6 0.2 0.0 0.7 0.2 2.3 3.1 1.9 11.1 3.1 0.5 0.1 2.2 0.9 0.8 0.0 0.4 0.0 0.7 0.0 0.9 0.7 1.0 0.5 0.7 0.0 1.2 1.5 1.1 1.0 0.3 0.0 4.0 3.8 14.1 28.3 41.4 31.6 14.3 16.3 19.6 17.7 47.3 22.1 DNPEP "ASPEP, DAP" ENSG00000123992 "Aspartyl aminopeptidase" Q9ULA0 2 219373527-219400022 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036398, HPA044860" Enhanced Supported Cytosol 6200000 Cytosol "HPA036398: AB_10970915, HPA044860: AB_10961275" "unprognostic (3.71e-1)" "unprognostic (6.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.75e-1)" "unprognostic (2.54e-3)" "unprognostic (3.34e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" "unprognostic (1.61e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-1)" "unprognostic (5.63e-3)" "unprognostic (3.49e-1)" "unprognostic (2.50e-1)" "unprognostic (1.85e-3)" 20.1 12.3 8.8 15.5 10.4 7.2 20.0 7.2 9.3 16.5 30.4 8.6 13.8 27.9 15.1 13.3 16.9 15.3 16.6 22.9 10.4 6.8 21.2 33.5 15.5 11.7 10.5 7.2 19.4 19.0 9.7 11.0 28.5 9.4 21.0 15.8 15.9 18.7 14.7 36.6 14.6 50.3 12.9 6.8 17.5 15.2 33.7 9.3 11.3 15.0 20.0 17.4 20.7 13.1 11.6 16.1 5.8 15.0 15.7 15.7 10.9 16.0 8.8 5.4 16.1 14.4 11.9 43.0 8.0 16.2 20.9 22.1 24.3 21.2 9.8 17.3 16.6 15.8 6.5 18.3 7.6 19.2 4.6 15.9 9.0 26.4 38.2 13.1 11.4 19.3 19.5 21.5 18.0 14.3 17.9 15.8 10.7 34.9 20.0 14.6 8.9 5.5 26.0 12.4 12.9 11.6 25.0 6.8 9.2 9.3 30.8 11.3 9.0 14.5 7.9 20.1 16.6 10.5 11.5 17.7 10.3 7.0 28.6 12.6 8.5 5.8 13.2 5.4 13.6 15.0 15.4 10.2 11.0 15.0 16.1 11.6 12.0 15.7 1.0 15.7 12.2 5.8 12.6 10.9 8.8 10.4 7.2 9.3 10.4 6.8 10.5 7.2 9.4 9.3 DOLPP1 LSFR2 ENSG00000167130 "Dolichyldiphosphatase 1" Q86YN1 9 129081100-129090438 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019179 Approved Approved "Vesicles,Intermediate filaments" Vesicles "Intermediate filaments" "HPA019179: AB_1847827" "unprognostic (1.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.89e-1)" "unprognostic (6.12e-3)" "unprognostic (3.11e-1)" "unprognostic (2.63e-2)" "unprognostic (3.18e-1)" "unprognostic (3.10e-2)" "unprognostic (6.96e-2)" "unprognostic (7.12e-2)" "unprognostic (1.65e-1)" "unprognostic (4.37e-3)" "unprognostic (7.59e-3)" "unprognostic (2.38e-2)" "unprognostic (1.35e-1)" "unprognostic (4.69e-2)" "unprognostic (5.34e-2)" 6.4 12.8 10.0 6.8 10.6 7.7 6.8 11.7 19.3 8.3 17.1 17.7 8.6 28.6 6.0 7.4 18.8 6.6 9.2 4.1 10.1 10.7 9.4 21.8 6.7 6.6 13.2 10.6 7.7 10.5 10.4 6.9 11.6 12.5 10.0 14.2 6.1 10.3 5.8 5.2 10.3 27.7 6.3 15.2 8.5 11.8 12.2 11.0 9.4 6.3 8.5 9.1 7.8 8.0 8.8 12.5 9.8 8.3 7.9 21.7 7.2 4.3 16.6 16.3 14.9 5.5 4.7 18.9 10.7 6.2 20.3 11.3 21.3 14.4 8.3 9.4 6.6 31.3 16.7 8.9 8.6 9.8 10.3 11.0 11.2 16.3 9.7 11.3 13.7 5.0 12.5 13.3 10.6 9.0 18.1 8.4 5.7 21.8 13.0 11.8 14.0 13.5 15.3 13.2 15.0 7.4 7.0 18.6 12.2 13.4 12.3 4.5 22.5 7.5 7.4 17.5 8.4 16.4 14.4 10.5 20.0 12.7 7.7 2.3 11.5 4.4 6.8 9.8 8.9 8.1 21.7 8.8 10.9 10.8 8.5 6.0 11.1 10.5 1.4 7.9 8.3 12.5 10.1 7.2 10.0 10.6 11.7 19.3 10.1 10.7 13.2 10.6 12.5 11.0 DPEP1 ENSG00000015413 "Dipeptidase 1" P16444 16 89613308-89638456 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "intestine: 161.7;kidney: 52.2;pancreas: 100.5" "Cell line enhanced" "Detected in some" "CACO-2: 5.1;Hep G2: 19.9;HHSteC: 9.0;U-937: 28.3" "Cancer enriched" "Detected in many" 8 "colorectal cancer: 107.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009426, HPA012783" Enhanced Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" 270000 "Nucleoplasm, Cell Junctions" "HPA009426: AB_1847842, HPA012783: AB_1847843" "unprognostic (3.31e-2)" "unprognostic (3.86e-1)" "unprognostic (1.37e-1)" "unprognostic (1.95e-2)" "unprognostic (1.91e-2)" "unprognostic (4.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (3.45e-2)" "unprognostic (5.18e-1)" "unprognostic (8.68e-2)" "unprognostic (1.27e-1)" "prognostic favourable (6.84e-4)" "unprognostic (6.12e-3)" "unprognostic (1.92e-1)" "unprognostic (5.23e-2)" "unprognostic (3.93e-2)" 0.1 0.4 0.1 0.9 0.1 0.0 0.1 0.1 0.1 1.5 53.6 0.1 0.4 16.1 0.2 3.4 0.3 0.1 0.9 0.1 0.1 0.1 52.2 0.1 0.3 0.9 0.1 0.1 0.2 100.5 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.3 0.4 0.1 0.4 161.7 0.1 0.1 0.9 0.2 9.8 0.1 0.2 0.1 0.1 0.5 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.0 1.1 0.1 2.8 0.0 0.0 0.0 0.0 5.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 19.9 9.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 DPEP2 ENSG00000167261 "Dipeptidase 2" Q9H4A9 16 67987394-68000586 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 105.1" "Cell line enhanced" "Detected in some" "HEL: 4.3;HMC-1: 19.5;NB-4: 4.2;U-937: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 43.5;eosinophil: 105.1;neutrophil: 47.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 105.1" "Low region specificity" "Detected in many" HPA035644 Approved 260000000 "HPA035644: AB_10670164" "unprognostic (8.81e-2)" "unprognostic (7.84e-5)" "unprognostic (1.35e-1)" "unprognostic (1.42e-2)" "unprognostic (1.92e-1)" "unprognostic (6.66e-3)" "unprognostic (1.03e-1)" "unprognostic (5.47e-2)" "unprognostic (3.69e-2)" "unprognostic (1.68e-1)" "unprognostic (6.01e-2)" "unprognostic (1.46e-1)" "unprognostic (3.91e-2)" "unprognostic (5.75e-2)" "prognostic unfavourable (8.47e-4)" "unprognostic (7.78e-3)" "unprognostic (3.91e-2)" 7.8 0.9 1.3 7.1 2.4 13.0 3.5 0.7 2.5 1.5 2.6 2.4 1.1 1.7 4.1 4.1 1.8 2.0 6.8 2.4 1.6 1.3 2.0 2.0 11.4 10.4 2.1 2.0 0.7 0.9 0.1 0.9 19.4 2.7 2.4 2.4 5.1 2.8 0.4 1.6 1.2 10.1 2.3 3.3 26.4 1.6 2.5 1.6 3.5 2.5 3.8 11.1 6.3 1.5 5.0 4.3 105.1 15.3 5.6 4.9 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.3 0.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 4.3 0.0 0.1 0.0 0.1 19.5 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 4.2 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.0 1.1 0.5 0.3 0.0 6.5 0.0 43.5 10.7 105.1 2.3 13.0 2.7 4.1 4.0 1.9 4.3 5.0 4.9 2.5 47.3 5.6 15.3 0.6 4.0 5.7 1.3 2.4 0.7 2.5 1.6 1.3 2.1 2.0 2.7 1.6 DPEP3 ENSG00000141096 "Dipeptidase 3" Q9H4B8 16 67975663-67980829 "Enzymes, Predicted intracellular proteins" Meiosis "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 56.7" "Cell line enriched" "Detected in single" 11 "U-266/70: 4.8" "Group enriched" "Detected in many" 10 "melanoma: 3.7;ovarian cancer: 16.9;testis cancer: 5.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 9.2;NK-cell: 2.3" "Group enriched" "Detected in many" 7 "granulocytes: 9.2;NK-cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031870, HPA058607" Enhanced "Intracellular and membrane" 16000000 "HPA031870: AB_2674079, HPA058607: AB_2683775" "unprognostic (9.93e-2)" "unprognostic (2.81e-3)" "unprognostic (1.86e-1)" "unprognostic (9.52e-2)" "unprognostic (3.61e-2)" "unprognostic (1.37e-2)" "unprognostic (1.55e-1)" "unprognostic (6.52e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.49e-3)" "unprognostic (9.97e-2)" "unprognostic (1.56e-1)" "unprognostic (3.15e-3)" "unprognostic (1.13e-1)" "unprognostic (3.98e-2)" "unprognostic (1.51e-1)" 0.2 0.0 0.1 0.4 0.4 1.0 0.6 0.1 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.6 0.0 0.3 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.0 0.2 0.3 0.1 0.1 0.0 0.5 0.0 0.4 1.4 0.2 56.7 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.8 0.1 9.2 0.5 2.3 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.2 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.5 0.3 0.4 0.0 0.0 0.1 0.8 0.8 0.3 9.2 2.3 0.1 0.0 0.0 0.3 0.1 0.4 0.1 0.3 0.3 0.1 0.1 0.0 0.9 0.1 DPH7 "C9orf112, FLJ90634, RRT2, WDR85" ENSG00000148399 "Diphthamide biosynthesis 7" Q9BTV6 9 137554904-137578935 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022911 Uncertain Approved "Nuclear bodies" "Nuclear bodies" "HPA022911: AB_1858823" "unprognostic (1.43e-1)" "unprognostic (4.81e-2)" "unprognostic (3.41e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-1)" "unprognostic (6.60e-3)" "unprognostic (1.48e-2)" "unprognostic (1.78e-1)" "unprognostic (2.14e-2)" "unprognostic (9.48e-2)" "prognostic favourable (6.52e-4)" "unprognostic (2.10e-2)" "prognostic unfavourable (1.52e-5)" "unprognostic (2.30e-3)" "unprognostic (3.06e-2)" "unprognostic (2.15e-1)" "prognostic favourable (3.23e-4)" 8.2 12.7 12.1 14.0 16.4 8.2 10.7 15.9 17.8 13.3 12.7 21.5 14.3 5.9 14.2 17.8 9.4 18.2 10.3 12.6 14.0 7.6 11.1 11.0 10.4 13.0 19.1 11.5 17.3 20.8 14.1 14.9 10.5 12.8 15.6 11.9 10.8 16.1 15.4 9.6 13.5 12.2 14.6 9.0 16.0 11.8 10.1 18.6 11.2 13.8 5.8 13.9 10.9 11.7 10.8 14.2 15.6 9.2 9.3 13.5 8.8 7.4 7.8 12.7 11.4 9.2 7.0 14.7 7.4 7.2 12.5 10.7 15.5 7.5 14.6 13.4 7.8 17.9 14.8 12.6 10.0 11.8 17.2 6.2 10.5 5.6 10.4 13.8 13.2 7.2 11.3 8.3 15.9 16.6 12.3 7.8 8.7 21.1 10.4 15.1 14.7 16.6 18.7 6.7 11.9 10.4 7.0 14.5 13.2 11.4 9.7 8.3 14.0 13.7 7.9 9.9 8.0 11.4 14.2 6.4 12.5 16.3 5.1 9.5 9.3 15.6 8.9 9.7 10.9 9.2 11.6 10.8 13.5 12.7 10.4 9.5 11.5 11.7 2.3 9.3 6.4 14.2 9.3 8.8 12.1 16.4 15.9 17.8 14.0 7.6 19.1 11.5 12.8 18.6 DPP3 ENSG00000254986 "Dipeptidyl peptidase 3" Q9NY33 11 66480013-66509657 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035780, HPA035781" Approved Supported Cytosol 2600000 Cytosol "HPA035780: AB_2674778, HPA035781: AB_10669529" "unprognostic (5.74e-2)" "unprognostic (1.16e-3)" "unprognostic (2.62e-3)" "unprognostic (4.77e-2)" "unprognostic (1.99e-1)" "unprognostic (5.44e-3)" "unprognostic (1.67e-3)" "unprognostic (1.25e-3)" "unprognostic (1.73e-2)" "unprognostic (9.87e-2)" "unprognostic (1.02e-2)" "unprognostic (3.87e-1)" "unprognostic (5.85e-2)" "prognostic favourable (1.34e-4)" "unprognostic (1.81e-2)" "unprognostic (3.43e-1)" "unprognostic (5.66e-2)" 10.4 13.0 5.2 16.8 12.1 10.9 16.9 13.7 11.5 7.3 18.5 9.1 10.3 15.3 10.5 6.8 15.6 7.1 15.7 8.4 9.3 5.9 18.4 31.1 9.8 20.0 9.5 10.6 5.1 11.6 11.2 6.9 10.9 7.4 10.3 16.9 5.7 17.6 8.5 15.8 9.4 15.5 10.0 10.6 12.5 11.8 15.5 6.7 16.1 10.5 10.8 14.0 11.4 8.6 7.5 19.7 12.2 24.4 18.2 17.9 9.9 28.5 24.8 11.5 12.8 9.6 10.4 17.9 16.2 21.8 21.9 14.6 31.2 24.0 16.6 55.2 18.3 25.7 18.3 19.8 14.1 31.5 8.3 21.6 11.6 18.3 14.8 26.1 36.1 14.7 19.4 16.4 8.2 16.7 15.1 9.9 19.9 32.4 30.4 26.6 19.6 15.2 21.5 11.6 27.2 18.8 24.6 21.8 18.7 13.8 16.1 21.6 25.0 15.3 17.4 13.1 14.3 14.4 15.8 8.3 15.1 18.9 17.4 12.5 16.1 9.6 11.3 12.2 13.7 24.4 8.4 7.5 10.3 11.4 19.7 7.2 6.3 9.2 2.0 18.2 16.0 13.7 17.9 9.9 5.2 12.1 13.7 11.5 9.3 5.9 9.5 10.6 7.4 6.7 DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992241-162074542 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 133.1;parathyroid gland: 75.5" "Cell line enhanced" "Detected in some" "ASC diff: 41.8;ASC TERT1: 42.4;BJ hTERT+: 38.9;RPTEC TERT1: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "MAIT T-cell: 26.7" "Lineage enriched" "Detected in many" 10 "T-cells: 26.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB045970 Enhanced "Secreted in other tissues" 170000000 "CAB045970: AB_11140529" "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavourable (1.98e-4)" "prognostic favourable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favourable (4.99e-4)" "unprognostic (1.21e-2)" 9.5 2.9 0.3 3.2 0.5 0.0 5.0 0.3 1.4 2.2 50.0 0.2 36.9 19.1 2.2 3.5 1.2 1.2 5.2 2.1 0.4 0.3 29.1 12.2 5.4 2.1 0.4 0.2 2.7 1.8 75.5 0.3 24.0 0.2 21.1 2.8 0.6 46.9 38.8 2.4 4.4 133.1 0.9 0.8 5.0 1.2 0.6 0.1 6.2 1.0 1.4 1.1 1.0 2.6 0.1 2.1 0.3 0.0 2.6 26.7 2.5 0.0 0.0 0.1 0.0 41.8 42.4 0.1 7.7 38.9 2.1 7.6 7.8 0.2 0.0 2.9 13.4 0.2 0.1 0.0 1.3 2.4 0.1 0.0 0.0 11.7 17.1 0.0 0.0 4.8 0.0 13.1 0.1 1.2 0.0 0.0 0.7 0.0 0.7 0.1 0.4 16.0 0.0 0.0 0.1 56.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.9 4.5 0.2 0.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 3.2 0.0 26.7 0.1 8.3 5.2 0.6 0.0 8.3 3.3 0.3 2.6 0.0 2.1 0.9 2.5 0.3 0.5 0.3 1.4 0.4 0.3 0.4 0.2 0.2 0.1 DPP7 "DPP2, DPPII" ENSG00000176978 "Dipeptidyl peptidase 7" Q9UHL4 9 137110542-137115177 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 56.7;THP-1: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021282, CAB025541, HPA059381" Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" 1300000 "Golgi apparatus, Vesicles" "CAB025541: , HPA021282: AB_1847673, HPA059381: " "unprognostic (1.15e-1)" "unprognostic (5.54e-2)" "prognostic unfavourable (6.07e-6)" "unprognostic (6.78e-3)" "unprognostic (1.25e-1)" "unprognostic (8.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.10e-2)" "unprognostic (2.28e-2)" "unprognostic (5.71e-3)" "prognostic favourable (8.31e-5)" "unprognostic (7.99e-2)" "unprognostic (1.46e-2)" "unprognostic (2.56e-2)" "unprognostic (1.72e-1)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" 28.1 45.2 23.7 23.4 35.3 31.8 20.8 23.5 27.5 21.5 22.0 24.9 40.7 23.2 17.5 35.8 19.1 27.0 30.2 44.7 24.6 29.2 21.0 29.9 25.6 34.8 29.7 25.9 14.3 55.4 23.3 42.5 21.9 24.2 28.8 6.9 32.8 73.1 41.6 25.3 26.9 17.8 22.8 21.7 29.1 24.4 30.9 26.8 18.9 41.2 17.5 24.7 21.3 16.6 20.0 60.8 12.2 43.1 19.2 36.8 38.2 6.8 10.9 0.9 0.9 13.5 10.8 1.4 10.4 17.0 6.9 4.5 10.3 5.7 13.6 11.4 6.8 14.9 8.0 2.0 0.3 13.3 0.5 6.2 15.0 0.3 30.2 16.8 34.9 13.3 8.3 3.0 6.2 9.0 13.6 10.6 4.6 19.0 8.4 16.0 3.7 10.7 12.4 0.1 56.7 11.0 7.7 17.4 12.1 12.0 31.6 29.4 11.3 54.5 10.9 17.7 6.0 11.2 7.2 13.0 7.4 3.6 21.2 10.2 7.9 6.8 43.1 12.2 34.4 37.6 35.5 19.7 31.1 29.6 41.7 20.0 28.1 25.1 2.6 19.2 22.6 60.8 36.8 38.2 23.7 35.3 23.5 27.5 24.6 29.2 29.7 25.9 24.2 26.8 DPP8 "DP8, DPRP1, FLJ14920, FLJ20283, MGC26191, MSTP141" ENSG00000074603 "Dipeptidyl peptidase 8" Q6V1X1 15 65442463-65517704 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008706 Approved Supported Cytosol Cytosol "HPA008706: AB_1078665" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.60e-2)" "unprognostic (2.98e-1)" "unprognostic (2.46e-1)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (4.09e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-2)" "unprognostic (1.01e-1)" "unprognostic (7.58e-2)" "unprognostic (8.56e-2)" "unprognostic (2.59e-1)" 15.6 16.1 16.4 14.9 18.8 16.2 13.9 22.9 24.9 15.5 14.5 15.0 12.7 18.0 15.9 13.9 13.1 11.1 12.4 18.8 15.1 14.6 16.0 9.9 13.3 16.0 15.4 11.8 16.2 11.7 22.2 14.5 15.9 21.7 13.5 15.8 13.9 15.6 20.8 30.5 14.2 16.5 16.2 17.5 17.2 13.2 29.9 15.8 22.5 17.4 12.5 16.0 16.2 13.2 10.7 8.1 20.0 10.8 6.1 10.3 5.3 9.4 15.3 10.1 10.1 11.4 16.4 8.6 15.3 18.1 13.7 13.2 6.6 8.2 16.7 12.1 19.1 17.7 19.5 11.0 16.8 14.1 12.1 16.1 11.8 6.3 11.9 20.7 15.9 12.2 10.5 11.1 10.5 15.0 10.9 15.6 16.8 7.6 11.0 7.6 6.9 7.9 14.7 18.7 16.2 11.3 20.6 7.2 12.7 9.9 10.1 15.4 9.3 12.4 18.9 18.4 12.9 8.7 16.3 20.2 26.4 17.0 13.9 20.9 13.2 20.0 9.1 11.1 9.9 9.2 10.3 9.2 8.6 9.5 8.1 10.7 8.6 9.2 18.3 6.1 10.8 7.5 8.9 5.3 16.4 18.8 22.9 24.4 15.1 14.6 15.4 11.8 21.7 15.8 DPP9 ENSG00000142002 "Dipeptidyl peptidase 9" Q86TI2 19 4675224-4724673 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036059 Approved Supported Cytosol Cytosol "HPA036059: AB_10671240" "prognostic favourable (4.96e-4)" "unprognostic (4.16e-2)" "unprognostic (2.03e-1)" "prognostic favourable (6.21e-5)" "unprognostic (5.67e-2)" "unprognostic (8.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (8.85e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-1)" "unprognostic (3.39e-2)" "prognostic unfavourable (3.38e-8)" "prognostic favourable (7.72e-5)" "unprognostic (1.55e-1)" "unprognostic (4.22e-1)" "unprognostic (1.80e-1)" 18.1 11.9 11.7 24.3 14.0 25.8 13.7 13.0 12.5 12.6 16.3 14.2 15.8 18.3 15.3 10.5 17.4 11.6 13.5 19.7 11.0 7.2 13.5 38.6 19.3 20.7 14.7 7.1 13.5 15.5 9.5 9.8 15.2 11.7 14.0 13.1 14.2 13.1 12.9 46.4 21.5 18.9 14.2 9.3 21.0 14.7 7.1 13.9 24.3 14.6 16.3 17.0 16.0 21.7 10.3 9.0 10.0 10.5 13.4 13.8 8.0 23.5 18.8 5.5 8.7 8.5 11.9 10.1 13.8 18.4 23.3 15.2 16.9 18.3 11.2 10.5 17.8 16.1 11.3 63.6 14.3 14.3 10.9 8.1 10.3 14.4 13.0 14.2 17.8 9.1 14.8 36.4 21.6 21.0 11.2 24.9 20.1 6.4 16.5 9.2 11.4 28.0 10.3 11.9 13.0 12.1 16.2 7.9 7.1 11.9 21.6 9.1 5.9 11.9 16.9 20.9 9.1 32.3 27.5 17.4 18.1 11.2 20.4 16.5 17.5 10.0 8.8 9.4 13.8 10.5 10.5 10.3 6.4 11.2 9.0 6.8 6.3 9.9 4.7 13.4 7.8 4.3 11.3 8.0 11.7 14.0 13.0 12.5 11.0 7.2 14.7 7.1 11.7 13.9 DPYS DHPase ENSG00000147647 Dihydropyrimidinase Q14117 8 104330324-104467053 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "kidney: 42.2;liver: 103.6" "Cell line enhanced" "Detected in some" "HDLM-2: 2.7;HSkMC: 2.4;U-266/84: 2.0" "Group enriched" "Detected in some" 21 "liver cancer: 57.6;renal cancer: 11.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "intermediate monocyte: 1.2" "Lineage enriched" "Detected in single" 13 "monocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA024785 Enhanced 89000 "HPA024785: AB_1847856" "unprognostic (1.54e-3)" "unprognostic (2.33e-1)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-1)" "unprognostic (2.38e-3)" "unprognostic (4.16e-4)" "unprognostic (1.56e-1)" "unprognostic (3.53e-2)" "unprognostic (3.85e-3)" "unprognostic (2.43e-1)" "unprognostic (4.81e-2)" "unprognostic (9.56e-3)" "unprognostic (2.72e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-1)" 2.5 0.6 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.2 2.1 0.1 0.0 0.0 0.0 1.6 0.1 0.2 1.3 0.0 0.0 0.1 42.2 103.6 0.2 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.1 0.1 0.9 0.0 0.2 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.7 0.0 0.0 1.2 0.0 0.0 2.7 0.0 0.1 0.0 0.2 0.0 1.3 1.1 2.4 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 1.4 0.0 0.7 0.1 0.6 1.3 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.0 1.5 0.0 0.7 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 DQX1 FLJ23757 ENSG00000144045 "DEAQ-box RNA dependent ATPase 1" Q8TE96 2 74518131-74526336 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 41.0" "Group enriched" "Detected in some" 4 "HBEC3-KT: 6.4;Hep G2: 18.0;hTCEpi: 6.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039158 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA039158: AB_10960125" "unprognostic (2.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (9.95e-2)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-1)" "unprognostic (4.54e-2)" "unprognostic (1.68e-1)" "unprognostic (7.67e-2)" "unprognostic (2.21e-2)" "unprognostic (0.00e+0)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-3)" 0.1 0.0 0.1 2.1 0.2 0.0 0.1 0.1 0.1 0.8 13.3 0.2 0.1 14.7 0.1 0.1 3.7 0.2 3.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 1.0 0.1 0.2 5.1 0.1 0.6 0.1 0.1 1.5 41.0 0.3 0.1 0.2 2.9 0.1 0.1 0.2 0.1 0.7 1.5 1.1 1.4 0.7 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.5 0.1 0.3 0.0 0.0 0.7 0.1 6.4 0.1 0.0 0.3 0.4 0.1 18.0 0.0 0.2 0.3 0.0 6.6 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.0 1.2 0.0 0.1 0.0 2.5 0.0 0.6 0.0 0.0 0.8 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 DROSHA "Etohi2, HSA242976, RN3, RNASE3L, RNASEN" ENSG00000113360 "Drosha ribonuclease III" Q9NRR4 5 31400497-31532196 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, RNA-mediated gene silencing" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (8.37e-3)" "unprognostic (1.81e-1)" "unprognostic (9.56e-2)" "prognostic unfavourable (6.79e-4)" "unprognostic (5.40e-2)" "unprognostic (6.03e-2)" "prognostic unfavourable (1.39e-4)" "unprognostic (3.11e-1)" "unprognostic (4.08e-2)" "unprognostic (9.08e-2)" "unprognostic (1.86e-1)" "unprognostic (5.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (6.94e-2)" "unprognostic (2.32e-2)" 15.7 16.8 18.4 17.7 32.1 12.2 16.1 33.7 33.7 17.4 16.3 19.1 12.2 15.9 22.3 25.8 16.0 18.2 14.1 15.2 16.6 15.1 15.3 11.7 13.9 17.8 13.6 16.4 26.7 17.8 23.9 38.9 17.0 18.9 17.2 19.2 23.7 17.5 19.2 23.6 16.0 17.5 16.9 19.4 16.8 16.0 12.8 16.4 25.6 21.9 13.4 19.8 18.2 16.2 4.7 6.4 3.3 4.8 4.8 6.4 3.1 12.1 15.4 17.0 23.2 9.1 11.1 24.6 16.1 7.9 15.1 11.3 16.2 15.9 13.7 18.6 11.8 10.7 20.9 12.2 16.8 12.8 14.8 16.8 50.5 11.7 8.2 18.8 50.3 8.8 8.6 16.8 8.1 12.8 21.4 6.5 13.2 12.1 18.1 14.1 16.1 12.3 16.5 32.6 9.9 8.5 13.9 8.9 11.8 41.0 16.8 9.9 15.5 10.8 11.1 14.5 16.9 13.1 15.3 11.8 19.4 15.1 10.1 21.2 13.9 1.8 2.4 3.3 5.2 2.6 5.5 4.2 5.4 6.0 5.2 4.7 6.4 4.4 0.8 4.8 4.8 6.4 5.1 3.1 18.4 32.1 33.7 33.7 16.6 15.1 13.6 16.4 18.9 16.4 DTD1 "bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, MGC119131, MGC41905, pqn-68" ENSG00000125821 "D-tyrosyl-tRNA deacylase 1" Q8TEA8 20 18587893-18766644 "Enzymes, Predicted intracellular proteins" "DNA replication" "DNA-binding, Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA040981 Uncertain Uncertain Nucleoli,Cytosol 180000 "Nucleoli, Cytosol" "HPA040981: AB_10673268" "unprognostic (3.32e-1)" "unprognostic (1.05e-1)" "unprognostic (1.82e-1)" "unprognostic (5.94e-2)" "unprognostic (1.83e-1)" "unprognostic (2.90e-1)" "unprognostic (1.27e-3)" "unprognostic (9.67e-2)" "unprognostic (1.72e-1)" "unprognostic (1.81e-1)" "unprognostic (6.84e-2)" "unprognostic (1.32e-1)" "unprognostic (9.09e-3)" "unprognostic (2.42e-1)" "unprognostic (8.44e-2)" "unprognostic (2.59e-2)" "unprognostic (8.53e-2)" 14.9 17.7 25.2 13.6 26.5 13.6 19.7 22.4 35.4 13.5 13.7 22.2 10.5 10.6 14.4 17.2 18.8 14.5 11.1 16.7 24.7 29.5 20.1 9.4 13.7 15.5 25.2 30.4 19.1 19.7 20.3 23.7 12.7 27.3 13.6 16.0 17.1 17.6 12.4 22.5 17.6 9.8 15.0 30.9 12.7 16.3 20.6 14.4 4.8 29.5 24.9 17.4 13.4 12.6 20.9 27.5 29.9 20.6 16.4 22.5 12.6 18.5 20.9 20.6 20.2 8.8 16.4 11.5 16.4 15.2 13.1 14.4 13.6 14.5 0.0 11.2 15.3 10.5 16.4 34.8 13.8 9.0 11.8 20.7 4.8 22.7 27.9 16.0 11.2 13.0 28.0 14.7 54.4 22.2 12.9 24.1 19.0 27.2 3.4 29.2 19.1 46.0 0.0 30.7 15.6 19.9 10.0 28.2 21.3 8.8 24.4 42.4 13.9 10.0 21.8 17.3 9.4 22.1 22.2 19.4 19.2 10.3 11.9 18.8 14.3 29.9 14.5 10.4 22.2 20.6 22.2 20.9 21.7 22.5 27.5 17.8 16.0 16.7 17.1 16.4 20.5 6.4 16.1 12.6 25.2 26.5 22.4 35.4 24.7 29.5 25.2 30.4 27.3 14.4 DTD2 "C14orf126, MGC9912" ENSG00000129480 "D-tyrosyl-tRNA deacylase 2 (putative)" Q96FN9 14 31446036-31457510 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA001117 Approved Approved Vesicles Vesicles "HPA001117: " "unprognostic (2.56e-3)" "unprognostic (9.38e-2)" "unprognostic (1.27e-3)" "unprognostic (3.24e-2)" "unprognostic (8.45e-2)" "prognostic unfavourable (9.33e-4)" "unprognostic (3.04e-2)" "unprognostic (1.64e-1)" "unprognostic (8.74e-3)" "unprognostic (2.91e-1)" "unprognostic (5.28e-2)" "unprognostic (6.96e-2)" "unprognostic (1.24e-1)" "unprognostic (2.32e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "prognostic unfavourable (5.74e-6)" 11.9 11.0 12.4 6.8 16.0 2.9 13.1 9.1 19.6 6.7 6.8 15.2 3.8 5.6 8.0 7.7 9.9 7.5 6.9 6.0 13.2 11.0 8.6 11.6 10.0 8.0 13.6 8.9 8.6 9.9 8.3 9.6 6.2 13.3 8.8 8.2 7.1 10.3 6.1 2.3 8.2 5.3 8.3 10.9 6.7 5.7 14.6 9.9 12.3 9.4 2.8 7.8 7.5 6.5 6.4 6.6 3.5 4.8 6.9 9.1 4.8 8.4 7.1 6.2 8.1 11.6 9.8 4.3 7.8 7.6 6.2 5.5 3.8 8.1 16.1 5.3 8.8 8.2 9.9 8.7 10.6 8.7 4.4 4.6 5.2 21.5 12.5 9.2 5.7 11.0 10.0 5.4 12.4 9.0 8.9 7.7 8.2 10.2 13.3 8.3 8.4 7.4 9.1 4.6 8.4 11.5 7.4 9.4 6.2 12.7 16.6 8.9 15.2 4.9 6.5 6.8 6.0 5.4 6.7 9.6 17.8 15.7 3.0 8.5 10.9 3.5 4.8 1.7 4.0 4.1 5.6 4.9 5.9 4.3 6.6 6.4 9.1 6.0 3.0 6.9 2.0 4.0 2.9 4.8 12.4 16.0 9.1 19.6 13.2 11.0 13.6 8.9 13.3 9.9 DUPD1 DUSP27 ENSG00000188716 "Dual specificity phosphatase and pro isomerase domain containing 1" Q68J44 10 75037836-75058514 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "skeletal muscle: 38.9" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042964 Uncertain "HPA042964: AB_10795764" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (2.34e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 DUSP1 "CL100, HVH1, MKP-1, PTPN10" ENSG00000120129 "Dual specificity phosphatase 1" P28562 5 172768090-172771195 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 43.1;hTCEpi: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 326.0" "Lineage enriched" "Detected in all" 10 "granulocytes: 326.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069577 Approved Nucleoli,Cytosol Nucleoli Cytosol "HPA069577: " "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (9.73e-2)" "unprognostic (8.17e-2)" "unprognostic (4.64e-1)" "unprognostic (1.58e-3)" "unprognostic (4.18e-2)" "unprognostic (6.94e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (2.76e-2)" "prognostic unfavourable (3.11e-5)" "unprognostic (2.69e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-3)" 158.4 78.0 12.4 68.5 14.0 89.7 91.8 17.4 14.9 81.4 37.1 32.4 48.5 9.4 55.4 71.6 82.7 94.8 138.8 49.2 12.5 11.4 29.8 115.4 135.0 43.5 30.6 9.7 69.4 34.4 26.6 40.8 93.7 29.3 67.1 34.2 61.0 38.1 192.8 54.8 116.1 27.6 65.0 29.5 36.1 53.6 45.9 18.7 10.8 90.4 104.1 46.9 69.0 109.7 2.4 11.5 326.0 31.8 4.5 9.8 14.0 2.1 5.4 1.7 2.3 37.5 22.0 2.9 34.9 10.2 23.5 9.5 5.9 2.5 0.7 10.2 24.5 0.9 1.6 8.6 11.0 19.1 4.6 0.4 11.9 2.5 43.1 0.2 0.8 21.0 75.3 10.6 17.3 7.3 1.7 13.7 15.1 2.5 1.1 1.0 1.5 1.6 40.5 3.2 6.3 16.7 1.1 7.4 3.1 9.4 16.1 1.2 1.3 0.4 19.2 16.7 8.3 16.2 2.6 2.8 1.6 0.6 14.8 0.3 0.6 33.3 24.6 69.8 3.9 25.0 9.8 2.4 3.5 4.0 11.5 2.1 1.7 1.9 326.0 4.5 31.8 0.6 2.8 14.0 12.4 14.0 17.4 14.9 12.5 11.4 30.6 9.7 29.3 18.7 DUSP10 "MKP-5, MKP5" ENSG00000143507 "Dual specificity phosphatase 10" Q9Y6W6 1 221701424-221742176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 35.4" "Cell line enhanced" "Detected in many" "HaCaT: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 15.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016758 Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" Nucleoplasm "Golgi apparatus, Cytosol" "HPA016758: AB_1847880" "unprognostic (1.55e-1)" "unprognostic (2.73e-1)" "unprognostic (1.44e-1)" "unprognostic (6.65e-2)" "unprognostic (3.83e-2)" "unprognostic (2.85e-3)" "prognostic favourable (5.42e-4)" "unprognostic (2.89e-1)" "unprognostic (3.89e-2)" "unprognostic (9.68e-2)" "unprognostic (2.38e-2)" "unprognostic (1.05e-1)" "prognostic unfavourable (3.69e-4)" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (8.88e-3)" "unprognostic (1.97e-2)" 7.4 4.7 6.0 7.1 11.2 23.2 8.2 5.9 11.1 5.7 10.8 21.1 0.3 2.1 4.9 2.7 7.0 8.5 7.6 3.8 7.2 4.0 2.8 35.4 8.0 9.0 14.0 5.6 2.8 18.3 1.8 2.5 4.5 8.4 3.6 4.9 8.5 9.5 1.7 21.0 8.0 6.2 9.7 10.1 6.4 4.5 3.9 14.1 5.6 5.3 10.6 8.6 8.5 4.1 0.8 5.4 4.6 4.2 15.1 12.7 1.6 6.0 2.6 0.2 0.1 18.8 9.7 0.2 4.0 10.6 6.7 5.2 0.1 1.6 4.7 1.4 10.4 41.5 0.9 3.9 5.8 12.0 0.5 8.1 1.1 0.7 4.4 3.6 5.5 13.5 2.9 7.2 7.3 0.2 0.8 1.6 6.4 0.1 0.7 2.7 0.6 0.2 0.4 11.5 0.3 2.3 3.7 15.5 1.2 0.5 0.5 17.2 0.9 2.1 1.4 3.4 0.9 5.1 4.9 2.8 2.0 2.5 5.3 1.6 3.6 4.6 4.2 0.2 3.6 3.7 3.3 0.7 2.5 2.5 5.4 0.8 0.8 1.5 0.3 15.1 1.4 0.2 12.7 1.6 6.0 11.2 5.9 11.1 7.2 4.0 14.0 5.6 8.4 14.1 DUSP12 "DUSP1, YVH1" ENSG00000081721 "Dual specificity phosphatase 12" Q9UNI6 1 161749758-161757238 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008840 Uncertain Supported Nucleoplasm Nucleoplasm "HPA008840: AB_1847884" "unprognostic (3.51e-2)" "unprognostic (2.62e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (2.11e-1)" "unprognostic (4.04e-2)" "prognostic unfavourable (1.99e-5)" "unprognostic (1.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.25e-3)" "unprognostic (9.52e-2)" "unprognostic (2.42e-3)" "prognostic unfavourable (1.55e-7)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-1)" 15.6 12.1 15.0 16.0 17.2 37.8 21.2 27.2 20.3 14.0 14.2 13.9 16.6 11.7 19.5 14.0 12.7 15.6 12.1 11.9 12.6 12.7 14.0 11.4 14.1 18.5 18.6 13.1 18.4 16.7 10.7 18.7 16.4 14.7 13.6 16.0 15.2 13.8 15.1 8.6 12.6 14.4 16.5 12.0 17.4 13.8 8.2 19.4 11.1 15.9 9.4 18.4 14.4 14.1 16.0 17.8 18.7 15.4 23.1 19.4 10.6 18.0 17.0 18.6 12.5 9.9 10.8 17.6 14.4 18.8 22.2 17.2 24.1 15.8 10.9 15.0 17.5 13.0 14.4 17.7 21.7 14.2 12.8 9.8 15.5 15.6 21.1 20.8 9.8 14.6 19.4 19.3 34.8 15.4 17.3 12.0 15.9 16.8 12.1 23.6 29.7 24.7 17.9 18.2 17.9 12.5 22.2 11.9 25.3 12.2 20.5 23.8 17.8 24.0 10.7 19.2 17.9 14.9 30.6 20.3 16.8 26.1 11.9 21.1 18.9 18.7 13.9 10.2 16.1 15.4 19.4 15.5 18.1 15.3 17.8 16.0 17.5 19.1 5.5 23.1 9.2 8.2 15.3 10.6 15.0 17.2 27.2 20.3 12.6 12.7 18.6 13.1 14.7 19.4 DUSP13 "BEDP, DUSP13A, DUSP13B, FLJ32450, TMDP" ENSG00000079393 "Dual specificity phosphatase 13" "Q6B8I1, Q9UII6" 10 75094432-75109221 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 75.2;testis: 18.6;tongue: 26.0" "Cell line enhanced" "Detected in some" "BEWO: 4.9;EFO-21: 5.7;Hep G2: 11.9;K-562: 4.6;LHCN-M2: 10.6;RH-30: 9.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 39 "neutrophil: 3.9" "Lineage enriched" "Detected in single" 39 "granulocytes: 3.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "unprognostic (1.79e-1)" "unprognostic (2.39e-2)" "unprognostic (2.39e-1)" "unprognostic (7.07e-2)" "unprognostic (1.66e-3)" "unprognostic (2.47e-3)" "unprognostic (8.63e-2)" "unprognostic (1.97e-1)" "unprognostic (2.63e-2)" "unprognostic (1.27e-1)" "unprognostic (3.92e-1)" "unprognostic (2.22e-7)" "unprognostic (1.93e-2)" "unprognostic (1.54e-1)" "unprognostic (4.81e-1)" "unprognostic (2.09e-2)" 0.8 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.3 1.2 0.0 0.0 5.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.3 0.0 75.2 0.1 0.0 0.0 0.0 0.1 0.0 18.6 0.0 0.0 1.0 26.0 1.9 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 1.1 0.1 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 11.9 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 4.6 0.0 10.6 0.6 0.0 0.0 0.7 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 DUSP14 "MKP-L, MKP6" ENSG00000276023 "Dual specificity phosphatase 14" O95147 17 37489831-37513501 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 10.7;BJ hTERT+ SV40 Large T+ RasG12V: 12.5;HBF TERT88: 17.9;WM-115: 10.3" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019911 Approved Approved Nucleoplasm,Cytosol 44000 "Nucleoplasm, Cytosol" "HPA019911: AB_1847888" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.60e-1)" "unprognostic (3.22e-2)" "unprognostic (3.43e-3)" "unprognostic (2.02e-3)" "unprognostic (2.18e-1)" "unprognostic (2.59e-1)" "unprognostic (7.02e-3)" "unprognostic (3.81e-1)" "prognostic unfavourable (6.97e-9)" "unprognostic (7.93e-2)" "unprognostic (1.97e-1)" "unprognostic (1.73e-1)" "unprognostic (1.41e-3)" 4.7 3.7 3.3 2.1 6.6 1.1 3.9 1.8 8.0 3.3 1.0 1.5 0.1 0.7 2.7 1.2 7.2 11.7 5.1 2.6 2.3 2.1 6.5 2.4 1.0 1.9 2.5 3.0 2.9 1.7 3.3 11.6 2.6 1.4 1.4 1.6 2.8 1.1 1.7 8.4 0.9 3.5 2.7 1.7 1.0 3.5 0.8 2.3 8.3 6.1 4.3 1.9 1.0 0.5 0.0 3.2 0.0 0.4 0.4 0.5 1.7 0.1 0.4 0.8 0.0 0.5 1.5 8.0 6.1 10.7 12.5 0.9 1.8 0.1 0.7 5.8 1.3 0.1 4.7 17.9 0.1 0.5 0.0 1.0 2.0 0.8 0.4 1.2 4.7 2.9 3.8 2.0 0.2 0.4 0.0 7.9 0.3 0.8 0.2 0.2 0.0 0.7 0.5 0.2 2.6 0.7 1.3 0.1 0.4 0.7 1.1 0.6 1.0 0.7 8.6 2.0 0.1 4.0 0.0 0.2 0.1 0.0 0.0 10.3 0.0 0.0 0.9 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.2 0.3 0.2 3.2 0.4 0.0 0.0 0.0 0.5 DUSP15 "bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY" ENSG00000149599 "Dual specificity phosphatase 15" Q9H1R2 20 31847637-31870747 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 75.1" "Cell line enhanced" "Detected in some" "CACO-2: 5.3;REH: 17.4;SH-SY5Y: 5.0;SK-MEL-30: 4.3;U-2 OS: 4.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 14 "naive B-cell: 1.6" "Lineage enriched" "Detected in single" 14 "B-cells: 1.6" "Low region specificity" "Detected in all" HPA076649 Enhanced Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA076649: " "unprognostic (3.84e-2)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (9.01e-3)" "unprognostic (3.88e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (1.48e-5)" "unprognostic (7.31e-2)" "prognostic favourable (5.40e-7)" "unprognostic (2.79e-2)" "unprognostic (1.93e-1)" "unprognostic (3.11e-3)" "unprognostic (2.55e-1)" 1.1 2.1 2.8 0.6 4.0 0.5 1.3 1.2 3.7 1.6 0.8 4.2 6.9 0.9 1.4 10.4 0.6 0.7 1.1 2.7 2.8 3.1 15.4 0.6 0.8 1.0 4.9 2.3 2.1 1.8 10.6 2.7 1.1 5.9 1.9 0.5 5.3 2.1 9.3 2.4 0.7 1.0 2.3 5.2 1.0 1.1 75.1 1.4 0.0 3.5 0.1 0.6 0.7 0.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 1.6 0.0 0.3 0.0 0.0 0.0 0.9 0.0 5.3 0.1 1.0 2.2 0.3 0.0 0.4 0.0 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.7 0.7 0.0 17.4 2.0 0.1 0.0 0.0 2.4 5.0 2.8 0.0 4.3 1.3 1.0 0.0 0.0 4.2 0.0 0.0 1.8 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.0 1.2 3.7 2.8 3.1 4.9 2.3 5.9 1.4 DUSP16 "KIAA1700, MKP-7, MKP7" ENSG00000111266 "Dual specificity phosphatase 16" Q9BY84 12 12474210-12562383 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 24.2;RT4: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 6.9" "Lineage enriched" "Detected in many" 5 "T-cells: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020326 Approved Supported Nucleoplasm Nucleoplasm "HPA020326: AB_1847890" "unprognostic (8.05e-2)" "unprognostic (9.47e-2)" "unprognostic (1.49e-3)" "unprognostic (4.14e-2)" "unprognostic (9.86e-2)" "prognostic favourable (1.01e-4)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (2.82e-1)" "unprognostic (2.34e-3)" "unprognostic (6.35e-3)" "unprognostic (2.42e-1)" "unprognostic (1.46e-1)" "unprognostic (5.76e-2)" 6.4 32.8 6.3 14.8 7.5 3.4 12.5 16.4 7.1 8.8 13.1 6.7 9.5 13.6 11.0 9.1 9.5 6.8 12.3 5.8 6.7 5.4 6.6 34.2 17.0 13.2 8.0 3.6 8.5 13.9 11.6 31.4 21.3 7.7 13.9 11.7 9.2 17.4 9.5 8.3 7.9 20.1 5.7 9.1 12.2 9.9 8.6 9.2 40.7 10.8 6.8 16.7 10.9 13.4 0.1 0.2 1.4 0.1 0.1 6.9 0.5 2.7 4.1 5.2 2.7 1.8 2.4 8.7 1.7 3.7 4.1 6.0 12.2 5.3 0.2 0.9 1.8 1.8 9.2 1.5 5.9 8.9 4.6 0.4 4.4 13.6 3.9 0.8 1.9 1.9 4.6 3.3 10.9 3.2 2.4 7.5 0.3 6.0 1.0 0.6 24.2 1.3 1.2 1.7 5.0 2.6 22.0 7.9 7.6 6.6 8.9 4.4 3.4 1.5 2.8 1.9 5.5 1.2 1.9 5.3 6.1 0.9 2.5 1.8 2.6 0.0 0.0 0.0 1.1 0.1 4.6 0.1 3.2 1.5 0.2 0.1 1.1 0.7 1.4 0.1 0.0 0.0 6.9 0.5 6.3 7.5 16.4 7.1 6.7 5.4 8.0 3.6 7.7 9.2 DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667890 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Nucleoplasm "CAB034070: AB_2094867, HPA051349: " "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (3.49e-3)" "unprognostic (4.88e-3)" "unprognostic (1.88e-1)" "unprognostic (9.12e-2)" "unprognostic (3.77e-4)" "unprognostic (1.83e-1)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (9.62e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-3)" "unprognostic (6.55e-2)" "unprognostic (1.97e-1)" "unprognostic (4.56e-2)" "unprognostic (1.02e-1)" 5.2 3.9 10.1 7.1 9.7 4.9 5.3 4.1 8.3 5.6 10.1 11.4 4.6 7.8 6.1 8.4 7.5 18.5 8.0 3.8 8.7 7.8 5.5 2.3 9.9 7.2 8.4 3.9 4.4 6.6 5.2 19.5 3.6 9.5 4.6 11.5 4.7 6.1 4.3 2.0 7.9 11.0 6.4 9.0 6.9 8.3 30.8 10.2 8.0 5.8 3.4 7.6 6.0 6.1 6.4 11.2 21.7 13.9 4.3 8.1 4.7 5.2 5.7 2.6 6.4 6.4 12.9 2.5 5.0 5.7 5.1 5.5 3.1 5.6 3.5 3.5 6.2 3.9 1.6 4.0 5.7 9.8 6.3 1.7 2.0 2.0 2.8 7.3 5.8 3.6 5.7 8.5 3.1 15.5 1.8 3.2 5.5 4.5 4.0 1.8 1.0 3.5 2.9 1.7 1.3 6.1 3.7 6.6 3.8 5.2 2.1 3.7 4.6 2.1 11.2 10.5 5.7 2.7 2.9 2.3 2.6 1.7 11.8 1.3 5.2 18.3 10.4 19.4 5.9 12.5 4.6 6.4 6.8 5.4 11.2 6.2 4.6 5.5 21.7 4.3 13.9 6.4 8.1 4.7 10.1 9.7 4.1 8.3 8.7 7.8 8.4 3.9 9.5 10.2 DUSP19 "DUSP17, SKRP1" ENSG00000162999 "Dual specificity phosphatase 19" Q8WTR2 2 183078559-183100005 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021501 Approved Approved Nucleoplasm Nucleoplasm "HPA021501: AB_1847892" "unprognostic (1.24e-1)" "unprognostic (2.13e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (5.18e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (8.30e-2)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (6.53e-2)" "unprognostic (5.80e-3)" "unprognostic (6.97e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-2)" "unprognostic (2.75e-2)" 2.8 4.6 9.2 2.0 16.3 1.0 3.0 2.9 9.6 3.4 4.7 2.2 3.8 3.5 6.8 9.2 4.2 8.4 3.5 7.4 17.4 3.4 4.7 3.0 3.4 2.3 3.3 6.8 4.4 4.3 7.7 10.6 2.7 3.7 4.2 3.0 3.0 2.8 5.4 3.8 3.4 3.0 8.6 2.9 4.0 9.1 10.4 4.7 6.2 4.6 1.1 1.9 4.0 2.7 4.1 1.5 2.0 0.8 2.2 3.2 1.3 0.1 2.4 2.8 1.4 3.9 2.2 0.0 1.1 1.8 4.5 1.6 2.2 2.9 1.0 5.9 1.2 0.3 5.7 0.8 3.5 5.7 3.1 10.5 1.8 1.6 1.7 2.6 6.5 1.7 0.5 2.3 1.1 2.6 3.1 1.6 2.7 1.0 4.9 2.5 2.4 2.0 4.9 4.5 0.3 1.0 1.1 3.6 1.5 3.9 1.6 2.8 0.8 1.0 2.0 2.4 2.1 1.6 0.9 2.0 2.4 0.1 3.1 0.4 3.7 2.0 0.5 1.9 2.3 0.8 2.3 4.1 2.1 3.1 0.6 2.2 2.7 2.7 1.3 2.2 0.4 1.5 3.2 1.3 9.2 16.3 2.9 9.6 17.4 3.4 3.3 6.8 3.7 4.7 DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143166-96145440 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 151.1" "Cell line enhanced" "Detected in many" "Daudi: 15.3;HeLa: 13.9;Karpas-707: 17.4;NB-4: 14.4;RT4: 17.3;SCLC-21H: 15.5;U-698: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "gdT-cell: 46.1" "Group enriched" "Detected in all" 10 "NK-cells: 29.6;T-cells: 46.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071920 Supported "Nucleoplasm,Nuclear membrane" "Nuclear membrane" Nucleoplasm "HPA071920: " "unprognostic (2.69e-3)" "unprognostic (6.70e-3)" "unprognostic (1.15e-1)" "unprognostic (5.46e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (3.66e-2)" "unprognostic (3.10e-1)" "unprognostic (6.30e-2)" "prognostic unfavourable (4.97e-5)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (1.31e-3)" 6.4 3.1 2.0 13.1 4.3 51.3 2.9 1.3 4.3 4.8 3.9 1.9 7.9 0.8 4.3 18.3 4.1 3.0 8.8 7.4 3.0 1.4 5.5 3.4 15.9 19.0 1.8 0.8 3.0 1.7 0.4 14.6 0.6 2.0 10.7 1.1 2.8 2.0 151.1 1.8 9.8 4.7 3.7 1.6 16.4 2.1 3.3 0.7 43.4 2.4 2.6 12.2 24.6 14.1 3.9 2.3 1.4 2.2 29.6 46.1 7.5 1.5 0.0 0.1 0.1 0.2 0.3 2.2 1.9 0.0 2.8 2.7 4.4 0.3 15.3 5.5 2.1 1.1 3.8 0.0 0.5 0.2 0.0 0.3 13.9 0.0 1.0 6.3 1.3 0.5 1.0 0.4 0.0 0.0 0.0 17.4 0.1 2.6 12.4 14.4 3.4 5.4 0.0 0.2 12.1 0.1 17.3 15.5 0.8 0.7 0.2 2.8 1.0 7.2 0.0 0.0 4.1 0.0 0.8 1.2 1.8 21.0 0.0 6.9 0.1 0.5 0.9 0.2 46.1 2.2 22.6 3.9 11.4 41.4 2.3 2.6 7.8 23.9 1.4 29.6 1.8 0.6 3.4 7.5 2.0 4.3 1.3 4.3 3.0 1.4 1.8 0.8 2.0 0.7 DUSP21 ENSG00000189037 "Dual specificity phosphatase 21" Q9H596 X 44844004-44844888 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "testis: 15.9" "Group enriched" "Detected in some" 5 "CACO-2: 1.7;K-562: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (5.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DUSP22 "JKAP, JSP1, MKPX, VHX" ENSG00000112679 "Dual specificity phosphatase 22" Q9NRW4 6 291630-351355 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 70.3;U-266/70: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031394 Approved Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA031394: AB_10604114" "unprognostic (7.34e-3)" "unprognostic (7.94e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (3.46e-1)" "unprognostic (1.70e-2)" "unprognostic (9.08e-3)" "unprognostic (2.48e-1)" "unprognostic (9.06e-2)" "unprognostic (5.56e-3)" "unprognostic (3.10e-2)" "unprognostic (3.04e-1)" "unprognostic (1.77e-1)" "unprognostic (3.97e-2)" "unprognostic (3.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.09e-1)" 24.8 13.1 22.0 24.6 31.3 19.4 28.7 12.1 27.5 18.1 29.0 29.8 18.8 21.2 20.6 25.2 29.8 15.0 20.4 31.0 22.6 17.4 16.0 20.3 24.6 27.4 33.5 16.1 13.9 27.9 10.8 14.8 25.9 25.5 16.1 15.9 16.9 20.9 15.5 32.0 30.6 21.8 23.4 29.2 30.0 21.4 41.3 30.0 9.2 19.9 19.0 27.9 22.8 27.4 21.6 18.0 16.3 17.5 2.9 8.2 9.8 3.5 2.2 4.7 7.0 5.4 6.1 6.2 2.6 2.1 2.3 2.8 2.3 4.0 7.5 6.4 2.7 2.5 5.9 4.9 1.7 17.9 6.8 5.1 1.7 6.4 2.8 1.8 6.7 4.5 14.8 1.7 3.1 6.7 4.7 25.2 1.9 2.1 2.6 6.5 2.8 5.1 5.3 3.2 70.3 4.4 1.5 8.1 3.2 2.2 0.9 7.7 4.7 2.3 9.1 2.1 2.8 2.1 1.6 35.8 25.2 10.4 0.8 5.0 4.7 16.3 17.5 6.9 5.0 14.0 3.5 21.6 3.9 5.1 18.0 17.5 3.6 5.1 12.0 2.9 12.6 15.4 8.2 9.8 22.0 31.3 12.1 27.5 22.6 17.4 33.5 16.1 25.5 30.0 DUSP23 "DUSP25, FLJ20442" ENSG00000158716 "Dual specificity phosphatase 23" Q9BVJ7 1 159780932-159782543 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 88.0" "Cell line enhanced" "Detected in many" "HSkMC: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028211, HPA045792" Approved Supported Nucleoplasm Nucleoplasm "HPA028211: , HPA045792: AB_10961133" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-2)" "unprognostic (4.36e-2)" "unprognostic (3.22e-1)" "prognostic unfavourable (3.06e-4)" "unprognostic (3.16e-1)" "unprognostic (4.62e-1)" "unprognostic (3.33e-3)" "unprognostic (4.72e-2)" "unprognostic (3.75e-2)" "prognostic unfavourable (2.59e-5)" "unprognostic (8.58e-2)" "unprognostic (2.84e-2)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" 25.0 28.0 7.6 9.3 10.5 11.2 27.3 4.4 9.0 15.5 15.9 5.9 6.6 17.2 12.2 15.0 21.2 10.9 12.6 14.9 7.8 5.2 88.0 80.8 12.1 15.4 8.5 4.6 12.3 21.5 12.5 4.3 7.4 9.6 18.0 9.1 9.5 37.8 10.9 32.8 15.8 16.1 7.7 9.6 8.7 11.0 9.7 7.3 5.7 27.0 17.4 11.4 10.5 19.1 13.6 59.7 49.9 43.2 21.3 24.0 24.0 12.2 13.2 0.1 0.0 12.9 11.0 0.1 5.0 4.1 5.9 4.6 5.3 14.0 0.0 29.9 5.4 0.5 3.4 4.5 3.2 3.0 1.5 16.8 4.7 0.0 19.2 10.1 12.9 46.6 12.2 3.8 13.8 22.4 7.6 6.1 8.2 22.1 1.0 0.4 22.7 18.8 0.0 0.0 5.7 7.1 2.1 5.7 12.7 9.0 19.9 23.2 12.8 15.9 16.4 4.9 0.2 0.6 0.0 4.3 10.3 0.1 8.3 8.2 3.7 20.0 43.2 49.9 24.0 33.4 13.3 13.6 18.1 22.5 59.7 9.8 11.0 16.4 43.2 21.3 22.1 13.6 15.7 24.0 7.6 10.5 4.4 9.0 7.8 5.2 8.5 4.6 9.6 7.3 DUSP26 "DUSP24, MGC1136" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591332-33600106 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 147.1" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 45.1" "Cancer enhanced" "Detected in some" "glioma: 6.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 16 "B-cells: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm Nucleoplasm "HPA018221: AB_2669813" "unprognostic (2.77e-4)" "unprognostic (2.70e-2)" "unprognostic (2.70e-3)" "unprognostic (5.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-2)" "unprognostic (2.81e-1)" "unprognostic (1.39e-1)" "unprognostic (4.10e-3)" "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.15e-2)" "unprognostic (5.80e-2)" 1.3 9.3 11.5 1.4 13.1 1.1 1.2 18.2 14.8 1.1 1.7 4.2 0.0 2.4 1.5 3.4 3.0 2.3 1.5 20.1 9.1 15.9 1.6 1.0 1.7 1.1 10.6 8.8 15.1 2.2 1.0 14.0 1.0 7.6 2.6 1.5 4.4 1.5 1.3 147.1 1.0 1.9 2.0 10.0 1.2 2.6 1.6 3.8 0.0 1.1 27.0 1.3 1.4 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 45.1 10.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 13.1 18.2 14.8 9.1 15.9 10.6 8.8 7.6 3.8 DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240564014 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" "Nuclear speckles" Cytosol "CAB069448: , HPA047456: AB_10961145" "unprognostic (1.88e-2)" "unprognostic (9.29e-2)" "unprognostic (4.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (7.56e-3)" "unprognostic (4.13e-3)" "unprognostic (3.71e-2)" "prognostic favourable (1.84e-4)" "unprognostic (9.85e-2)" "unprognostic (1.80e-3)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-3)" 1.8 2.8 2.7 3.0 3.4 7.9 3.5 6.3 3.7 3.1 2.6 3.3 6.5 2.9 2.6 5.0 3.5 3.1 4.4 16.3 2.8 2.7 3.2 3.4 2.5 6.1 3.5 2.4 2.6 10.2 2.6 5.0 3.2 2.8 4.3 2.8 2.7 3.7 2.4 21.2 4.9 4.2 4.3 2.2 5.9 4.2 8.2 2.3 2.6 4.4 13.4 4.2 2.8 4.5 3.8 3.3 10.7 2.1 2.7 3.3 2.0 1.7 1.6 2.2 2.5 1.4 0.7 2.3 1.9 1.1 1.5 1.1 0.9 4.4 2.7 1.0 1.2 4.9 1.7 0.6 1.6 3.3 6.2 3.8 3.3 2.4 1.0 2.5 6.6 1.6 1.7 1.0 1.3 0.7 2.7 3.2 1.3 1.8 3.1 4.0 1.4 1.4 3.8 4.7 3.6 1.1 2.9 4.8 2.7 1.8 1.9 2.1 2.3 4.3 1.7 3.5 2.8 2.2 1.7 12.9 3.7 4.3 2.1 1.9 2.7 10.7 2.1 0.7 2.7 1.4 3.0 2.1 2.8 2.8 1.2 3.8 3.3 3.0 3.6 2.7 1.5 3.3 2.2 2.0 2.7 3.4 6.3 3.6 2.8 2.7 3.5 2.4 2.8 2.3 DUSP3 VHR ENSG00000108861 "Dual specificity phosphatase 3" P51452 17 43766121-43778988 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 19.5;granulocytes: 5.2;monocytes: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063616 Supported Nucleoplasm,Cytosol 1300000 Nucleoplasm Cytosol "HPA063616: " "unprognostic (1.52e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (1.04e-3)" "prognostic unfavourable (3.00e-4)" "unprognostic (4.83e-2)" "unprognostic (8.98e-2)" "unprognostic (5.13e-1)" "unprognostic (6.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.40e-3)" "prognostic favourable (5.49e-5)" "unprognostic (2.67e-3)" "unprognostic (5.45e-2)" "unprognostic (1.94e-1)" "unprognostic (1.37e-2)" 17.1 17.8 23.1 10.2 20.8 4.6 22.0 14.3 28.6 12.8 28.4 11.1 16.7 13.4 17.5 18.7 23.6 10.6 19.3 64.0 21.5 18.1 27.1 39.9 17.2 9.0 17.6 19.1 9.1 19.2 27.5 11.4 15.0 17.1 22.6 13.1 14.3 11.1 36.6 106.9 8.9 15.2 31.1 12.7 14.5 19.6 8.0 10.8 1.2 13.9 22.8 6.5 20.7 24.1 1.7 19.5 5.2 17.0 0.9 1.7 5.8 10.9 19.8 7.6 8.1 22.3 12.0 6.5 8.3 19.9 19.4 23.5 19.0 7.4 1.7 13.2 15.5 9.5 11.8 10.2 20.5 3.7 9.0 5.5 9.1 15.5 27.3 0.6 5.7 11.1 18.4 14.9 13.1 13.5 4.9 1.9 22.6 7.8 2.8 2.8 3.5 14.5 3.6 23.0 4.1 26.9 11.5 4.3 7.7 9.7 6.5 24.4 29.1 15.4 14.0 22.0 14.9 31.2 13.7 10.2 13.4 0.4 26.1 7.7 7.3 5.2 17.0 3.5 1.0 8.9 1.7 1.7 1.5 1.2 19.5 1.6 1.2 1.1 4.1 0.9 10.8 8.2 0.9 5.8 23.1 20.8 14.3 28.6 21.5 18.1 17.6 19.1 17.1 10.8 DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350668 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 46.7;pancreas: 78.6;seminal vesicle: 63.5" "Cell line enhanced" "Detected in many" "A549: 30.0;SK-MEL-30: 46.2;WM-115: 37.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 8 "T-reg: 9.6" "Lineage enriched" "Detected in single" 18 "T-cells: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061967 Supported Nucleoplasm Nucleoplasm "HPA061967: " "unprognostic (1.92e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "unprognostic (6.54e-2)" "unprognostic (2.18e-2)" "unprognostic (7.66e-3)" "unprognostic (7.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.83e-2)" "unprognostic (9.73e-3)" "unprognostic (9.60e-3)" "unprognostic (3.15e-2)" "prognostic unfavourable (4.19e-4)" "unprognostic (6.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-2)" "unprognostic (6.07e-2)" 10.9 3.4 1.2 3.6 1.1 3.4 17.1 4.8 2.7 4.6 1.7 1.0 46.7 0.8 3.2 0.7 1.6 1.3 13.1 1.5 4.6 0.8 0.7 0.4 3.7 1.8 0.8 0.8 1.2 78.6 0.1 3.7 17.7 0.7 4.3 0.9 17.1 8.9 63.5 2.7 3.5 1.3 1.5 1.1 0.6 20.6 1.7 0.2 3.9 1.2 2.0 4.7 7.4 3.0 0.0 0.5 0.0 0.0 0.2 9.6 0.1 11.1 30.0 17.8 0.8 2.3 0.0 1.5 2.3 12.8 7.0 3.1 0.3 5.7 0.0 6.3 1.0 3.6 0.2 7.7 4.2 0.3 0.6 0.0 1.0 0.2 0.0 0.1 14.6 1.4 5.1 2.2 13.1 5.7 0.1 1.3 14.0 12.6 0.0 2.1 3.1 18.4 0.3 0.6 2.3 16.1 5.9 0.1 9.9 3.2 15.2 46.2 3.2 0.3 16.0 5.2 0.0 0.0 1.6 3.6 0.4 0.0 15.6 2.6 37.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 9.6 0.1 1.2 1.1 4.8 2.7 4.6 0.8 0.8 0.8 0.7 0.2 DUSP5 HVH3 ENSG00000138166 "Dual specificity phosphatase 5" Q16690 10 110497838-110511544 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 85.9;Karpas-707: 33.3;U-266/70: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 3.4;non-classical monocyte: 8.8;plasmacytoid DC: 13.3" "Group enriched" "Detected in many" 19 "dendritic cells: 13.3;monocytes: 8.8;T-cells: 3.4" "Region enhanced" "Detected in many" "cerebellum: 68.0" "Region enriched" "Detected in many" 5 "cerebellum: 41.9" "unprognostic (1.25e-1)" "unprognostic (3.57e-1)" "unprognostic (5.19e-2)" "unprognostic (1.03e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" "unprognostic (6.35e-2)" "prognostic unfavourable (8.30e-6)" "unprognostic (1.70e-2)" "unprognostic (4.60e-2)" "unprognostic (2.91e-2)" "unprognostic (1.20e-2)" "unprognostic (4.20e-3)" "unprognostic (3.79e-1)" "unprognostic (3.78e-3)" "unprognostic (2.32e-1)" "unprognostic (9.09e-2)" 13.7 11.0 2.8 12.4 5.1 14.5 11.2 19.8 5.2 15.1 12.5 3.3 7.7 5.4 9.1 8.8 55.5 5.6 24.2 11.3 5.2 3.3 9.1 13.1 12.1 9.3 2.9 2.8 6.5 3.9 5.5 8.0 45.1 5.6 15.6 12.4 21.0 9.4 10.0 1.8 6.5 17.6 10.3 7.1 11.4 10.2 13.1 2.1 4.8 7.8 21.9 47.8 31.6 14.3 0.2 13.3 0.4 8.8 0.0 3.4 0.5 4.3 2.9 0.6 1.5 2.3 9.9 2.2 10.3 23.5 5.6 6.7 1.8 5.9 0.5 1.9 2.5 1.4 0.5 5.4 9.1 12.4 0.3 2.4 0.5 1.1 8.9 0.6 3.1 3.8 7.4 17.8 85.9 3.5 0.4 33.3 16.7 1.1 0.1 1.8 1.9 4.5 0.0 1.3 7.6 19.1 8.5 0.3 0.8 0.6 1.6 3.4 0.9 0.7 5.3 1.9 1.3 4.5 4.9 47.5 8.4 1.2 7.3 3.3 1.3 0.4 0.2 0.0 3.4 2.0 1.2 0.2 1.8 1.0 0.9 0.0 0.0 1.1 0.1 0.0 8.8 13.3 0.0 0.5 2.8 5.1 19.8 5.2 5.2 3.3 2.9 2.8 5.6 2.1 DUSP6 "MKP-3, PYST1" ENSG00000139318 "Dual specificity phosphatase 6" Q16828 12 89347232-89353271 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 125.0" "Cell line enhanced" "Detected in many" "AN3-CA: 80.6;NB-4: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 125.0" "Group enriched" "Detected in many" 11 "granulocytes: 125.0;monocytes: 79.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017566, HPA053188, HPA064692" Approved Supported Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "CAB017566: AB_647991, HPA053188: , HPA064692: " "unprognostic (7.35e-2)" "unprognostic (1.50e-2)" "unprognostic (5.77e-2)" "prognostic favourable (7.21e-4)" "unprognostic (2.35e-3)" "unprognostic (2.10e-3)" "unprognostic (3.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.63e-2)" "unprognostic (1.67e-2)" "unprognostic (3.15e-3)" "unprognostic (2.09e-1)" "unprognostic (5.91e-3)" "unprognostic (1.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-2)" "unprognostic (2.84e-1)" 37.7 7.5 7.2 15.9 11.7 41.3 24.1 3.4 14.7 11.6 12.4 6.2 5.8 6.1 9.8 8.7 12.0 15.4 25.1 16.2 10.5 6.5 17.1 38.4 28.2 13.3 6.9 7.4 7.5 12.2 15.0 13.7 19.7 7.9 17.4 15.3 44.4 64.3 6.3 12.0 8.5 14.6 11.3 7.1 28.4 10.3 4.8 6.4 6.1 21.0 13.3 17.8 15.2 6.9 1.2 9.2 125.0 79.7 1.2 0.9 32.4 1.1 1.1 24.0 80.6 20.8 17.7 0.0 8.7 11.1 1.7 1.3 7.0 1.2 0.0 2.0 3.7 9.3 0.1 21.6 2.5 0.1 0.1 3.6 0.2 11.2 14.7 15.5 39.5 3.4 7.6 15.3 14.3 40.1 0.0 3.8 5.5 0.5 0.5 57.8 14.6 19.7 39.3 3.0 1.5 24.8 23.3 0.4 17.1 0.2 0.1 45.9 1.2 8.6 10.7 5.9 0.1 1.1 4.1 0.6 3.1 0.0 24.5 10.9 37.4 125.0 49.5 22.4 0.9 79.7 0.4 0.2 0.2 0.3 9.2 1.2 0.1 0.3 22.5 1.2 74.4 1.2 0.6 32.4 7.2 11.7 3.4 14.7 10.5 6.5 6.9 7.4 7.9 6.4 DUSP7 "MKP-X, PYST2" ENSG00000164086 "Dual specificity phosphatase 7" Q16829 3 52048919-52056550 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 40.7;hTERT-HME1: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073007 Approved "HPA073007: " "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (6.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (8.67e-3)" "unprognostic (7.38e-3)" "unprognostic (7.74e-3)" "prognostic unfavourable (8.84e-6)" "unprognostic (4.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-2)" "unprognostic (9.46e-2)" 5.5 5.9 7.8 4.3 8.5 1.6 3.7 6.5 19.2 8.6 2.9 15.3 3.4 2.4 5.6 2.4 22.0 4.4 5.3 8.3 7.3 4.8 3.6 2.5 7.0 5.6 9.9 10.0 4.7 4.3 3.9 3.8 8.9 4.9 4.0 2.3 4.6 5.2 5.3 11.4 24.1 3.5 4.2 4.8 10.7 3.7 5.4 9.2 3.2 3.4 15.0 8.6 5.8 14.7 1.0 7.5 1.7 10.7 2.3 8.2 1.7 7.4 1.6 1.9 4.3 6.2 5.4 2.3 7.6 14.5 7.6 5.5 2.0 3.8 2.0 2.1 11.2 8.9 7.2 27.5 5.2 1.7 2.9 9.9 3.8 3.6 5.0 8.8 6.0 5.6 40.7 9.8 34.6 7.2 5.6 6.0 6.0 2.0 6.5 12.4 4.7 13.7 5.5 1.6 5.5 3.1 3.2 2.4 7.0 3.4 3.1 5.3 1.1 21.2 9.4 14.6 9.4 15.3 23.1 2.9 2.7 3.4 8.1 14.9 4.6 0.9 3.9 1.7 6.0 10.7 8.2 1.0 7.2 4.3 5.0 0.6 5.3 4.8 1.4 2.3 10.0 7.5 4.6 1.7 7.8 8.5 6.5 19.2 7.3 4.8 9.9 10.0 4.9 9.2 DUSP8 "C11orf81, FLJ42958, HB5, HVH-5" ENSG00000184545 "Dual specificity phosphatase 8" Q13202 11 1554044-1571920 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2" "Cell line enhanced" "Detected in some" "MCF7: 6.1;SH-SY5Y: 5.4;U-251 MG: 2.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020071 Approved Approved Cytosol Cytosol "HPA020071: AB_1847903" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (4.00e-2)" "unprognostic (1.35e-1)" "unprognostic (7.58e-3)" "unprognostic (6.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (4.04e-3)" "unprognostic (1.82e-1)" "prognostic favourable (2.75e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (8.65e-2)" "unprognostic (6.30e-2)" 6.3 2.2 18.8 3.2 18.8 7.5 3.5 20.0 30.2 1.9 4.3 4.2 1.4 1.7 5.9 4.8 3.5 4.0 5.4 5.7 16.6 9.3 2.6 3.7 3.6 3.5 5.5 11.2 2.2 12.7 1.7 10.8 2.8 5.1 3.0 4.1 2.7 5.1 2.7 6.1 3.2 6.3 9.3 3.6 6.3 4.3 2.4 5.1 0.0 2.6 2.2 2.3 2.7 1.6 0.1 0.1 0.0 0.0 0.0 0.7 0.0 1.8 0.8 1.0 0.1 0.0 0.1 2.2 0.1 1.1 0.4 1.2 0.0 0.0 0.1 0.0 0.3 1.2 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.2 0.4 0.1 0.0 1.8 0.0 6.1 0.0 0.4 0.0 1.9 0.1 0.1 0.7 0.0 0.2 0.0 5.4 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 1.0 2.3 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 18.8 18.8 20.0 30.2 16.6 9.3 5.5 11.2 5.1 5.1 DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "kidney: 23.0;placenta: 63.1" "Cell line enriched" "Detected in some" 9 "Hep G2: 88.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 7 "amygdala: 4.4;basal ganglia: 2.7;cerebral cortex: 3.5;hippocampal formation: 3.7;hypothalamus: 3.6" HPA003336 Enhanced Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavourable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" 0.2 0.1 3.2 0.2 4.4 0.1 0.3 0.2 2.0 0.2 0.1 0.7 0.0 0.2 0.1 0.3 0.3 0.2 0.1 0.2 2.5 0.6 23.0 0.7 0.2 0.2 1.1 0.6 1.9 0.5 0.1 0.0 63.1 0.9 0.2 0.1 0.0 0.8 1.5 0.1 0.2 0.2 0.1 0.5 0.2 0.2 1.1 0.8 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 8.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.5 0.5 0.0 3.9 0.0 1.8 9.8 0.2 0.0 0.2 1.8 0.0 0.7 88.7 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.5 0.0 0.1 0.2 3.6 0.0 0.0 0.0 0.0 2.2 0.1 0.3 0.5 0.7 0.3 0.1 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 4.4 0.2 2.0 2.5 0.6 1.1 0.6 0.9 0.8 DUT dUTPase ENSG00000128951 "Deoxyuridine triphosphatase" P33316 15 48331011-48343373 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054422, HPA060360" Enhanced Supported Nucleoplasm Nucleoplasm "HPA054422: , HPA060360: " "unprognostic (1.82e-1)" "unprognostic (3.49e-2)" "unprognostic (7.89e-2)" "unprognostic (5.27e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (4.42e-3)" "unprognostic (1.87e-2)" "unprognostic (4.25e-1)" "unprognostic (3.54e-2)" "unprognostic (3.68e-2)" "unprognostic (4.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-2)" "unprognostic (1.71e-2)" 26.9 32.9 23.2 51.1 31.8 69.0 31.9 31.7 27.6 26.8 26.3 24.4 27.2 14.5 29.8 31.8 33.7 26.9 28.2 35.5 23.2 26.5 25.4 19.8 25.7 44.7 25.3 23.6 33.4 22.2 23.7 30.7 26.0 22.5 30.3 24.3 28.1 27.5 26.1 25.6 27.3 22.6 25.6 23.9 30.1 25.8 31.9 20.7 120.3 40.5 37.7 43.2 23.5 28.4 34.5 32.3 17.0 24.5 22.2 40.2 24.3 25.6 8.1 19.7 18.7 13.8 14.8 11.7 27.2 17.4 25.2 31.3 9.3 17.7 71.6 14.7 14.9 35.3 20.6 18.6 24.7 50.4 21.3 58.4 21.3 12.6 7.7 61.2 27.8 9.0 12.7 17.0 9.0 16.7 31.6 40.7 18.5 10.4 54.7 72.1 12.4 15.6 44.6 43.2 75.2 16.5 17.4 28.6 29.1 20.2 16.4 23.3 23.1 48.9 13.8 26.4 25.5 31.4 35.7 32.9 68.3 70.5 20.0 105.1 28.9 11.3 19.5 17.0 21.7 19.3 28.1 34.5 38.9 34.2 28.2 31.6 40.2 26.5 11.1 22.2 24.5 32.3 34.4 24.3 23.2 31.8 31.7 27.6 23.2 26.5 25.3 23.6 22.5 20.7 ECE1 ECE ENSG00000117298 "Endothelin converting enzyme 1" P42892 1 21217247-21345504 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 114.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 101.6;TIME: 90.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 21.5" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001490, HPA013616" Enhanced 2100000 "HPA001490: AB_1078718, HPA013616: AB_1847963" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (1.49e-2)" "unprognostic (1.46e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (9.10e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-2)" 44.0 49.9 10.3 18.7 14.5 17.3 33.7 3.6 15.6 29.5 27.5 19.2 11.2 12.4 24.0 10.5 15.6 19.1 23.0 30.9 12.4 8.0 14.9 41.8 30.1 14.4 13.9 13.4 34.2 42.1 114.4 21.6 27.0 14.6 27.9 14.6 26.5 14.7 11.4 15.2 14.8 23.2 24.1 13.2 23.5 18.9 19.1 14.7 9.5 23.2 10.7 19.1 34.2 37.0 4.6 2.0 21.5 7.5 1.0 6.1 4.2 13.6 9.2 11.8 5.9 17.1 18.2 6.8 20.3 35.5 11.1 10.2 6.6 42.0 4.9 51.2 20.5 5.8 4.8 9.7 9.7 12.4 4.0 7.1 14.2 5.3 22.8 1.0 1.8 9.5 11.4 17.1 8.5 101.6 1.4 2.6 9.4 2.8 2.0 1.6 3.6 7.2 2.5 6.8 7.1 17.3 2.5 4.0 9.8 20.2 11.9 8.8 8.5 2.9 90.1 25.0 12.2 11.0 11.7 4.1 6.9 5.7 52.0 2.4 30.2 0.1 5.8 2.2 2.2 7.5 3.3 4.6 4.6 3.5 0.5 3.1 3.1 1.9 21.5 1.0 5.2 2.0 6.1 4.2 10.3 14.5 3.6 15.6 12.4 8.0 13.9 13.4 14.6 14.7 EDEM3 C1orf22 ENSG00000116406 "ER degradation enhancing alpha-mannosidase like protein 3" Q9BZQ6 1 184690231-184754913 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025754, HPA025755, HPA027297" Approved Approved "Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "HPA025754: AB_1845638, HPA025755: AB_1845639, HPA027297: " "unprognostic (1.74e-1)" "unprognostic (1.64e-2)" "unprognostic (3.08e-2)" "unprognostic (2.67e-2)" "unprognostic (2.30e-1)" "unprognostic (3.10e-2)" "unprognostic (7.52e-3)" "unprognostic (1.82e-1)" "unprognostic (7.06e-2)" "unprognostic (1.66e-1)" "unprognostic (1.66e-1)" "unprognostic (3.53e-2)" "prognostic unfavourable (1.63e-6)" "unprognostic (4.72e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-2)" "unprognostic (2.01e-1)" 12.5 12.6 10.8 11.3 13.8 6.4 11.1 15.2 11.8 13.2 17.6 7.5 10.8 16.0 11.7 7.7 10.9 10.2 10.4 10.4 9.1 8.2 9.6 27.8 13.3 8.9 13.5 8.4 8.8 27.3 18.4 26.4 17.9 10.6 12.3 21.3 7.6 18.3 14.3 20.8 7.1 14.4 10.6 13.3 9.5 31.3 6.2 11.5 15.8 11.5 6.3 10.6 11.6 16.1 2.7 5.9 7.4 6.8 4.0 6.3 3.4 6.5 4.9 6.8 6.0 24.9 25.7 11.1 13.3 9.2 5.1 5.3 2.6 18.9 4.6 14.5 10.0 8.9 6.5 6.9 7.5 4.4 5.3 6.0 5.2 3.7 9.6 15.6 8.8 14.6 8.5 12.3 11.0 13.6 15.7 21.3 9.6 5.4 12.5 8.2 9.5 4.6 5.5 5.2 15.5 7.3 4.6 7.7 10.9 6.5 11.3 9.2 10.6 24.6 15.9 7.3 3.3 15.4 11.1 32.7 12.6 6.0 9.7 17.9 15.9 7.4 6.8 4.1 2.9 6.7 5.1 2.7 4.5 3.5 5.9 2.0 6.3 3.3 6.9 4.0 6.3 3.0 3.0 3.4 10.8 13.8 15.2 11.8 9.1 8.2 13.5 8.4 10.6 11.5 EIF3F "eIF3-epsilon, eIF3-p47, eIF3f, EIF3S5" ENSG00000175390 "Eukaryotic translation initiation factor 3 subunit F" O00303 11 7970251-8001862 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis, Ubl conjugation pathway" "Hydrolase, Initiation factor, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049250 Approved 18000 "HPA049250: " "unprognostic (1.11e-2)" "unprognostic (1.42e-1)" "unprognostic (8.46e-2)" "unprognostic (1.15e-2)" "unprognostic (8.50e-2)" "unprognostic (2.26e-1)" "prognostic unfavourable (6.86e-4)" "unprognostic (1.16e-1)" "unprognostic (1.97e-1)" "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.04e-1)" "unprognostic (1.57e-1)" "unprognostic (5.66e-2)" "unprognostic (2.61e-1)" "unprognostic (8.36e-2)" "unprognostic (8.78e-2)" 38.2 28.5 19.8 40.4 22.0 36.6 50.8 16.4 22.7 44.4 41.4 23.2 35.0 25.4 40.6 35.7 45.8 41.1 42.6 38.6 17.0 14.7 29.7 32.2 33.9 82.2 19.9 20.4 74.6 67.4 23.0 23.5 28.9 17.8 45.0 31.2 26.2 49.2 29.7 71.4 56.8 31.7 54.2 20.1 37.1 40.9 42.5 20.0 88.5 50.8 47.7 51.6 48.0 55.5 60.4 48.1 14.7 35.6 34.7 65.7 70.3 29.8 19.2 31.0 23.0 39.8 74.2 28.8 23.9 35.1 26.2 26.2 20.0 41.5 52.8 12.6 29.3 21.7 20.9 45.2 33.2 15.5 39.2 22.9 23.0 29.7 68.2 29.3 23.0 59.3 44.1 14.8 49.0 32.5 18.6 22.4 32.8 20.1 34.2 39.3 28.1 28.7 43.4 17.7 20.4 26.3 30.9 20.6 42.9 13.5 23.5 25.3 19.7 22.3 24.6 18.4 27.9 12.3 17.6 20.7 27.2 26.1 19.4 14.4 24.6 14.0 35.2 14.7 31.9 35.6 44.7 60.4 54.6 39.8 48.1 53.7 65.7 48.3 5.4 34.7 32.9 34.6 60.5 70.3 19.8 22.0 16.4 22.7 17.0 14.7 19.9 20.4 17.8 20.0 EIF4A1 "DDX2A, EIF-4A, EIF4A" ENSG00000161960 "Eukaryotic translation initiation factor 4A1" P60842 17 7572706-7579005 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011689, HPA068286" Uncertain Approved Cytosol 2300000 Cytosol "CAB011689: AB_732122, HPA068286: " "unprognostic (1.49e-2)" "unprognostic (2.41e-1)" "unprognostic (8.00e-2)" "unprognostic (2.17e-1)" "unprognostic (2.49e-1)" "unprognostic (2.12e-3)" "unprognostic (7.25e-2)" "unprognostic (2.89e-2)" "unprognostic (2.72e-2)" "unprognostic (2.11e-2)" "unprognostic (2.65e-2)" "unprognostic (5.19e-3)" "prognostic unfavourable (1.76e-8)" "unprognostic (1.91e-1)" "unprognostic (5.96e-2)" "unprognostic (1.16e-1)" "unprognostic (1.13e-2)" 56.5 49.0 19.3 41.4 19.8 51.4 80.2 13.6 26.6 40.4 45.6 28.5 26.4 28.7 45.9 30.2 76.4 43.4 39.2 33.5 18.5 17.1 34.2 58.0 46.3 135.7 27.7 12.9 55.2 77.0 19.8 28.8 45.2 21.8 36.2 44.0 33.0 65.8 30.7 36.5 48.4 30.9 46.5 33.4 46.8 42.2 31.6 21.8 91.5 34.7 73.8 67.7 42.5 40.8 35.1 143.6 29.1 115.7 47.1 60.3 170.1 84.2 115.6 77.5 70.2 69.7 81.7 72.4 81.4 92.6 150.9 116.7 116.6 38.2 115.4 62.7 85.3 75.7 164.4 125.3 162.7 37.3 121.9 65.0 75.2 129.6 106.9 66.4 65.8 108.2 64.8 126.8 129.7 113.2 66.3 23.9 108.6 88.6 68.9 57.0 66.4 80.1 65.1 58.5 55.4 105.5 77.5 41.0 79.6 73.3 49.4 102.0 54.8 51.1 80.9 79.8 55.7 51.0 163.6 23.5 32.8 75.6 85.8 81.8 87.4 19.6 115.7 29.1 37.0 102.6 60.3 35.1 40.0 39.5 143.6 28.9 39.4 39.6 12.1 47.1 75.7 54.8 49.2 170.1 19.3 19.8 13.6 26.6 18.5 17.1 27.7 12.9 21.8 21.8 EIF4A2 "BM-010, DDX2B, EIF4A, EIF4F" ENSG00000156976 "Eukaryotic translation initiation factor 4A2" Q14240 3 186783205-186789900 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB011690, HPA068286" Uncertain Approved Cytosol 1000000 Cytosol "CAB011690: AB_732123, HPA068286: " "unprognostic (1.49e-1)" "unprognostic (9.62e-2)" "unprognostic (3.78e-2)" "unprognostic (9.50e-3)" "unprognostic (2.82e-2)" "unprognostic (1.10e-2)" "unprognostic (4.46e-2)" "unprognostic (6.27e-2)" "unprognostic (4.32e-3)" "unprognostic (1.00e-1)" "unprognostic (6.39e-2)" "unprognostic (3.99e-2)" "unprognostic (6.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.03e-1)" "unprognostic (4.67e-2)" "unprognostic (2.62e-2)" 34.6 66.1 61.2 27.7 79.9 1.9 53.5 121.1 111.5 65.1 52.1 26.5 30.1 30.3 73.1 45.5 44.5 73.9 45.1 83.7 58.4 71.9 63.9 43.5 33.7 36.1 48.9 61.7 142.0 59.0 30.9 84.1 47.3 69.6 57.9 40.1 31.8 43.7 62.8 126.7 19.8 35.6 57.1 41.9 32.5 39.0 32.9 39.5 23.9 67.8 36.4 35.4 61.1 51.7 55.1 19.3 39.4 24.8 33.0 63.4 51.3 10.5 5.3 22.3 3.6 85.9 81.0 6.8 19.0 17.2 20.2 26.6 19.6 3.8 23.6 106.5 27.3 17.8 32.7 8.0 35.6 22.0 17.2 38.0 7.1 26.3 33.7 8.0 26.7 54.2 38.5 5.8 48.6 35.8 12.8 39.8 65.6 1.8 12.7 3.9 22.1 25.5 16.3 15.8 14.3 40.0 12.9 43.9 8.8 30.9 21.3 40.4 33.2 29.3 26.1 16.0 8.0 15.4 11.6 31.7 44.8 10.8 11.0 8.4 7.5 39.4 16.0 18.5 28.5 18.2 45.3 55.1 41.9 34.8 19.3 46.1 63.4 50.2 11.0 33.0 24.8 17.4 38.6 51.3 61.2 79.9 121.1 111.5 58.4 71.9 48.9 61.7 69.6 39.5 EIF4A3 "DDX48, EIF4AIII, Fal1, KIAA0111" ENSG00000141543 "Eukaryotic translation initiation factor 4A3" P38919 17 80135214-80147183 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, rRNA processing, Translation regulation, Transport" "Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021878 Supported Supported Nucleoplasm 73000 Nucleoplasm "HPA021878: AB_1848090" "unprognostic (7.24e-2)" "unprognostic (7.33e-3)" "prognostic favourable (3.57e-5)" "unprognostic (1.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.52e-2)" "prognostic unfavourable (1.68e-5)" "prognostic unfavourable (1.87e-4)" "unprognostic (3.71e-1)" "unprognostic (5.06e-2)" "unprognostic (4.64e-2)" "unprognostic (2.64e-2)" "unprognostic (9.78e-3)" "unprognostic (5.81e-2)" "unprognostic (9.20e-2)" "unprognostic (1.38e-2)" "unprognostic (2.91e-3)" 27.3 37.0 19.6 23.6 21.5 71.7 22.0 20.3 19.8 24.2 23.8 16.9 19.2 16.2 24.9 18.0 41.5 29.4 17.1 24.2 17.8 12.3 24.5 20.3 21.6 25.4 16.8 19.7 37.5 16.8 17.1 21.9 38.3 13.1 24.7 20.9 14.7 22.1 31.2 19.8 31.2 18.6 18.5 13.7 25.5 20.4 35.1 19.3 30.7 26.9 26.4 30.6 28.9 25.8 38.7 80.4 33.1 41.9 30.2 38.9 48.3 47.5 42.7 28.2 20.9 21.7 13.3 24.7 25.3 18.0 35.9 28.9 45.5 22.3 43.6 17.0 22.1 31.8 38.7 27.0 40.0 16.1 40.5 27.3 33.8 49.0 21.4 49.1 28.6 20.3 13.9 30.0 24.4 29.3 36.3 28.3 21.2 36.4 44.3 25.0 30.3 39.6 36.7 57.2 34.4 17.5 40.8 39.4 21.5 34.8 68.1 29.2 44.5 33.1 20.1 22.3 28.6 32.8 39.8 24.8 21.4 80.5 18.0 31.1 22.8 25.7 41.1 33.1 26.7 41.9 34.5 38.7 34.5 30.8 50.3 31.6 32.0 30.7 24.4 30.2 32.9 80.4 38.9 48.3 19.6 21.5 20.3 19.8 17.8 12.3 16.8 19.7 13.1 19.3 EIF5B "DKFZp434I036, FLJ10524, IF2, KIAA0741" ENSG00000158417 "Eukaryotic translation initiation factor 5B" O60841 2 99337353-99401326 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034648, HPA040095" Approved Approved "Plasma membrane,Cytosol" 11000 Cytosol "Plasma membrane" "HPA034648: AB_10601902, HPA040095: " "unprognostic (1.23e-1)" "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (5.03e-2)" "unprognostic (4.65e-2)" "unprognostic (5.88e-3)" "prognostic unfavourable (7.15e-10)" "unprognostic (6.80e-2)" "unprognostic (9.84e-3)" "prognostic favourable (8.99e-4)" "unprognostic (1.68e-2)" "unprognostic (2.36e-1)" "prognostic unfavourable (1.42e-6)" "unprognostic (6.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.43e-1)" "unprognostic (7.93e-3)" 24.5 16.0 25.2 22.4 32.6 11.5 22.6 27.7 26.0 23.7 25.1 10.5 19.9 14.8 19.4 28.7 30.8 14.5 15.0 61.7 26.0 22.3 28.8 32.1 17.9 19.2 26.9 23.0 22.3 24.6 26.8 27.5 26.4 28.5 26.0 20.3 7.1 22.3 29.1 105.8 25.3 19.3 31.5 37.6 27.0 20.7 22.6 33.8 17.8 18.2 29.2 22.8 40.1 31.9 15.9 20.2 11.6 12.1 14.1 14.9 4.5 33.7 16.9 19.3 25.1 23.4 27.8 32.0 29.8 18.8 19.9 19.8 38.9 24.2 38.7 25.9 22.2 19.4 33.7 28.9 35.2 23.4 20.2 46.5 17.3 51.1 18.6 45.5 28.8 18.7 20.4 27.6 28.3 28.9 51.3 19.4 28.5 27.4 28.8 42.2 30.1 24.9 25.2 28.7 31.6 40.7 28.4 16.4 15.5 16.2 37.4 24.0 15.2 30.1 31.7 30.9 30.3 16.1 26.5 14.4 20.4 31.6 22.5 50.5 22.7 11.6 8.8 9.8 12.7 9.5 14.9 15.3 13.4 12.5 6.4 15.9 13.2 14.0 2.3 14.1 12.1 20.2 9.0 4.5 25.2 32.6 27.7 26.0 26.0 22.3 26.9 23.0 28.5 33.8 ELAC1 D29 ENSG00000141642 "ElaC ribonuclease Z 1" Q9H777 18 50967991-50988121 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040867, HPA066483" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA040867: AB_10697716, HPA066483: " "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "unprognostic (6.95e-3)" "unprognostic (1.75e-2)" "unprognostic (8.61e-2)" "unprognostic (5.96e-2)" "unprognostic (3.25e-1)" "unprognostic (3.03e-3)" "unprognostic (5.87e-2)" "unprognostic (2.82e-3)" "unprognostic (3.67e-3)" "unprognostic (6.36e-2)" "prognostic favourable (8.43e-8)" "unprognostic (3.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (3.87e-2)" 8.7 15.0 7.7 7.7 9.7 3.3 9.4 7.1 11.9 8.0 9.1 12.8 12.1 7.6 11.3 20.1 7.5 10.0 9.6 7.2 7.3 8.3 12.4 15.2 7.6 11.2 7.6 7.2 8.8 19.5 17.1 15.7 12.3 8.7 9.9 10.8 13.7 20.1 12.2 6.8 7.7 11.7 8.3 7.1 10.8 10.1 16.7 3.9 10.1 15.6 7.0 9.9 8.7 6.6 14.2 12.4 7.8 9.1 16.1 15.7 8.1 6.9 4.8 12.7 10.8 14.3 6.1 5.4 7.6 10.1 7.2 5.1 1.8 6.6 5.4 5.3 7.0 7.0 3.9 8.0 4.9 11.7 1.0 6.6 1.8 1.2 8.4 16.7 4.8 7.6 6.4 3.8 8.9 7.4 6.7 13.5 12.6 3.1 5.7 5.0 6.3 2.1 6.6 4.5 10.0 8.3 3.0 7.5 8.6 6.3 1.1 12.1 5.9 12.8 6.5 9.4 4.9 2.7 5.1 12.7 10.6 7.2 8.7 5.6 11.8 4.1 7.8 7.8 13.2 9.1 14.6 14.2 12.7 12.9 12.4 13.6 12.4 15.7 0.9 16.1 8.7 10.4 10.0 8.1 7.7 9.7 7.1 11.9 7.3 8.3 7.6 7.2 8.7 3.9 ELAC2 "FLJ10530, HPC2" ENSG00000006744 "ElaC ribonuclease Z 2" Q9BQ52 17 12992391-13018187 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Disease mutation, Primary mitochondrial disease, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019535 Approved Enhanced Nucleoplasm Nucleoplasm "HPA019535: AB_1848106" "unprognostic (4.24e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "prognostic favourable (3.24e-6)" "unprognostic (8.64e-2)" "unprognostic (1.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.47e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-1)" "unprognostic (5.31e-3)" "unprognostic (3.09e-1)" "unprognostic (5.31e-3)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (8.09e-2)" "unprognostic (3.70e-2)" 20.3 35.9 15.2 17.2 23.5 13.8 18.6 16.9 30.0 17.5 21.2 24.6 17.9 15.8 22.1 13.1 25.9 19.5 19.6 28.1 14.2 14.3 23.5 34.8 14.2 19.4 18.2 19.5 20.3 24.5 27.5 14.0 21.2 20.5 20.7 25.1 19.4 19.1 26.2 49.2 20.7 18.7 26.6 15.6 25.5 22.8 29.5 17.1 28.1 20.7 20.1 25.9 23.0 16.3 19.9 23.5 9.4 20.4 24.0 25.1 20.9 20.2 32.2 22.4 24.9 17.9 17.5 13.6 22.2 17.9 36.3 24.4 25.9 10.8 36.7 24.2 21.1 27.4 40.5 25.7 36.3 19.0 40.8 21.4 25.2 17.0 13.3 18.3 29.7 15.6 21.9 28.2 26.3 25.4 29.3 11.2 27.5 18.0 32.3 18.3 18.5 21.6 22.7 38.2 23.0 20.5 18.2 11.5 16.8 28.2 18.4 11.4 18.3 8.0 24.7 44.9 14.9 17.7 32.6 7.0 13.0 14.8 17.8 19.6 16.3 9.4 14.7 9.3 21.4 20.1 23.0 19.9 20.7 21.3 23.5 17.4 21.5 19.2 2.2 24.0 20.4 13.3 25.1 20.9 15.2 23.5 16.9 30.0 14.2 14.3 18.2 19.5 20.5 17.1 ELANE "ELA2, HLE, HNE, NE" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 244.3" "Cell line enriched" "Detected in some" 65 "THP-1: 193.2" "Group enriched" "Detected in some" 7 "pancreatic cancer: 3.5;stomach cancer: 3.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 3.2;neutrophil: 6.9" "Group enriched" "Detected in many" 9 "granulocytes: 6.9;monocytes: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB015409, HPA066836" Enhanced "Secreted to blood" 59000 "CAB015409: AB_831596, HPA066836: " "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.43e-2)" "unprognostic (3.92e-1)" "unprognostic (6.38e-3)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (3.48e-2)" "unprognostic (1.19e-10)" "unprognostic (6.27e-3)" "unprognostic (4.00e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-3)" 1.5 0.3 0.1 0.3 0.1 244.3 1.6 0.2 0.6 0.3 0.6 0.7 0.0 0.3 0.3 0.7 0.5 0.6 0.8 31.2 0.0 0.0 0.3 1.5 17.8 1.6 0.0 0.0 0.3 1.8 0.3 0.4 4.7 0.5 1.4 0.3 1.0 0.7 0.3 1.1 2.1 0.5 0.5 0.0 22.5 0.5 0.3 0.0 23.0 2.3 0.9 0.3 1.0 0.2 0.0 0.0 6.9 3.2 0.0 0.5 11.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 193.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.2 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 11.2 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.5 0.0 ENGASE FLJ21865 ENSG00000167280 Endo-beta-N-acetylglucosaminidase Q8NFI3 17 79074939-79088599 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 51.4" "Cell line enhanced" "Detected in many" "SK-BR-3: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021551 Approved Approved Centrosome,Cytosol "Centrosome, Cytosol" "HPA021551: AB_1848156" "unprognostic (7.49e-2)" "unprognostic (1.42e-1)" "unprognostic (5.65e-2)" "unprognostic (6.16e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-3)" "unprognostic (9.62e-2)" "unprognostic (4.09e-2)" "unprognostic (9.07e-2)" "unprognostic (7.00e-3)" "prognostic favourable (2.60e-4)" "unprognostic (4.79e-2)" "prognostic unfavourable (8.97e-6)" "unprognostic (8.38e-3)" "unprognostic (6.03e-1)" "unprognostic (2.06e-2)" "prognostic favourable (8.73e-5)" 10.0 10.1 9.5 20.7 18.4 8.9 11.4 7.0 13.9 10.9 15.1 12.4 8.8 20.3 11.4 6.8 6.5 10.6 8.6 10.3 9.3 5.8 9.2 10.2 10.1 10.7 16.8 8.5 16.3 9.3 11.3 9.8 8.1 13.6 12.3 12.5 10.7 12.1 9.6 35.4 11.9 17.3 7.3 11.9 24.9 11.4 3.9 14.0 8.1 13.6 7.0 9.1 17.5 51.4 0.2 0.7 0.0 1.1 0.0 2.1 0.6 4.5 9.6 3.4 6.2 3.6 1.5 6.5 3.4 1.7 2.8 2.0 5.1 4.9 0.0 4.2 3.5 6.7 5.4 3.7 1.6 2.7 7.2 4.0 9.8 3.0 2.7 4.6 7.7 4.0 5.2 2.4 2.7 2.9 5.8 2.8 1.8 3.8 0.4 4.4 1.5 8.7 8.5 11.6 2.9 1.5 12.7 2.8 5.7 5.5 25.5 2.5 9.0 4.4 3.8 5.5 4.1 4.8 3.4 6.8 1.2 1.9 2.3 8.5 4.0 0.0 0.7 0.0 0.0 1.1 0.9 0.0 0.1 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.5 0.6 2.1 0.6 9.5 18.4 7.0 13.9 9.3 5.8 16.8 8.5 13.6 14.0 ENOPH1 "E1, MASA, mtnC" ENSG00000145293 "Enolase-phosphatase 1" Q9UHY7 4 82430562-82461091 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004985, HPA044607" Enhanced Approved "Nucleoplasm,Nuclear bodies" 140000 Nucleoplasm "Nuclear bodies" "CAB004985: AB_426046, HPA044607: AB_2679019" "unprognostic (6.64e-3)" "unprognostic (3.05e-1)" "unprognostic (6.77e-3)" "unprognostic (1.05e-3)" "unprognostic (1.46e-1)" "unprognostic (1.68e-3)" "prognostic unfavourable (1.74e-5)" "unprognostic (9.99e-3)" "unprognostic (1.18e-1)" "unprognostic (2.17e-1)" "unprognostic (1.59e-1)" "unprognostic (2.05e-1)" "unprognostic (9.30e-3)" "unprognostic (3.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.52e-3)" "unprognostic (3.52e-2)" 10.2 15.4 43.4 12.1 37.1 14.3 16.3 22.9 38.8 13.8 12.7 34.7 5.1 12.2 10.5 23.3 13.5 10.4 9.0 11.1 44.2 34.9 20.8 13.3 11.1 16.0 47.5 26.4 12.9 14.6 17.8 11.7 17.7 31.0 17.2 15.3 8.9 11.4 11.9 9.8 13.1 11.0 11.1 66.2 12.8 13.2 6.1 29.4 14.2 18.0 8.2 18.6 10.7 9.5 13.0 14.1 4.3 10.4 14.4 20.2 12.2 18.8 12.5 22.4 13.9 13.7 13.5 24.6 22.0 14.7 20.1 18.0 22.7 21.1 37.5 23.1 16.6 10.2 29.6 27.8 36.4 22.6 13.8 22.7 12.2 30.2 22.3 37.6 19.7 13.0 29.6 21.0 24.9 20.3 29.3 20.7 26.2 24.3 41.4 22.4 20.6 10.1 29.6 34.4 20.4 32.8 18.7 31.8 19.4 12.5 37.8 27.9 17.1 18.2 14.9 25.0 18.5 24.7 28.9 23.8 20.4 46.8 16.1 23.4 33.5 3.4 8.7 4.3 14.4 10.4 18.0 13.0 17.3 16.5 12.7 11.0 20.2 16.2 0.7 14.4 8.8 14.1 18.4 12.2 43.4 37.1 22.9 38.4 44.2 34.9 47.5 26.4 31.0 29.4 ENPEP "CD249, gp160" ENSG00000138792 "Glutamyl aminopeptidase" Q07075 4 110365733-110565285 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 165.1;kidney: 63.8" "Cell line enhanced" "Detected in some" "BEWO: 4.5;HEK 293: 12.1;MOLT-4: 2.9" "Cancer enriched" "Detected in many" 8 "renal cancer: 41.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005128 Enhanced 37000000 "HPA005128: AB_1844795" "unprognostic (2.73e-3)" "unprognostic (2.84e-3)" "unprognostic (5.16e-3)" "unprognostic (3.48e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" "unprognostic (3.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.47e-2)" "unprognostic (4.49e-3)" "unprognostic (3.43e-3)" "unprognostic (1.52e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-3)" 5.8 1.0 0.4 0.4 0.6 0.0 2.8 0.3 1.0 1.1 54.4 0.4 0.7 11.1 5.3 2.4 0.8 1.4 1.1 2.3 0.5 0.3 63.8 14.5 2.7 0.5 0.4 0.3 1.0 1.0 33.3 0.8 4.4 0.5 1.4 0.0 0.8 0.6 0.5 2.3 0.4 165.1 3.1 0.5 4.7 0.7 0.4 0.4 1.4 2.4 2.0 0.4 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.1 0.0 0.1 0.3 4.5 0.6 0.0 0.2 0.4 0.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 2.9 0.5 0.5 0.0 0.2 0.0 0.5 0.0 0.5 0.1 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 2.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.3 1.0 0.5 0.3 0.4 0.3 0.5 0.4 ENPP1 "M6S1, NPPS, PC-1, PCA1, PDNP1" ENSG00000197594 "Ectonucleotide pyrophosphatase/phosphodiesterase 1" P22413 6 131808016-131895155 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" Biomineralization Hydrolase "Diabetes mellitus, Disease mutation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 22.6;LHCN-M2: 13.5;U-138 MG: 18.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "NK-cell: 4.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB032904, HPA062066" Enhanced "Secreted - unknown location" 2500000 "CAB032904: AB_2099635, HPA062066: " "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.60e-2)" "unprognostic (7.22e-3)" "unprognostic (8.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.00e-1)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (3.28e-3)" 17.2 2.1 0.5 1.9 0.5 0.0 30.5 0.6 0.4 8.5 2.8 1.6 8.3 1.1 25.7 7.1 1.5 6.4 2.6 1.9 0.5 0.7 10.9 19.4 2.0 0.7 1.1 0.0 7.3 17.5 22.2 27.0 28.9 0.8 3.3 1.2 13.4 5.4 6.5 2.1 1.7 2.6 6.8 2.0 1.2 1.7 4.6 0.3 2.0 13.2 6.9 1.4 3.2 7.7 0.6 2.2 1.4 0.3 4.6 1.7 0.1 0.0 0.8 0.8 0.0 22.6 3.5 0.0 5.8 6.0 2.3 6.3 2.5 0.7 0.0 0.5 3.7 0.0 0.8 0.1 9.7 0.2 1.1 0.0 0.7 7.5 0.7 0.0 2.7 5.8 0.2 6.2 0.2 2.7 0.0 1.2 13.5 1.6 0.0 0.0 5.1 0.8 0.0 6.6 0.1 0.1 0.3 2.2 0.0 0.1 0.8 2.6 2.5 0.0 1.8 18.1 0.6 1.2 5.7 2.2 0.0 0.0 8.3 0.0 2.2 1.4 0.2 0.3 0.3 0.2 1.7 0.3 0.3 0.3 2.2 0.6 0.3 0.3 1.0 4.6 0.3 0.3 0.2 0.1 0.5 0.5 0.6 0.4 0.5 0.7 1.1 0.0 0.8 0.3 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 103.7;placenta: 79.0" "Cell line enhanced" "Detected in some" "AF22: 24.7;ASC diff: 33.8;ASC TERT1: 72.2;BJ hTERT+: 41.5;fHDF/TERT166: 26.8;HSkMC: 33.1" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 26.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Intracellular and membrane" 1100000000 "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: " "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favourable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 29.9 15.4 24.0 18.2 42.0 0.7 26.2 4.4 33.3 19.6 8.1 103.7 1.7 20.8 44.8 6.4 2.9 18.7 12.7 3.6 39.8 21.5 24.9 8.9 13.5 31.0 71.5 20.9 5.3 5.2 0.9 4.1 79.0 59.7 8.5 10.6 67.6 3.4 9.2 3.0 5.4 12.1 28.9 102.4 17.3 8.3 9.7 63.9 3.6 3.7 0.8 26.1 13.4 5.7 0.2 3.8 26.8 0.1 0.2 1.8 0.3 0.0 0.0 24.7 0.0 33.8 72.2 0.0 22.7 41.5 9.8 9.4 0.0 0.0 0.0 0.3 26.8 0.0 0.5 0.0 6.9 1.8 0.7 0.0 0.0 0.6 15.1 0.0 0.1 33.1 0.2 20.0 1.0 0.1 0.0 4.0 0.5 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.4 23.9 0.1 0.2 0.0 0.0 16.8 0.1 0.5 26.8 0.1 5.2 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.0 1.8 0.6 0.3 0.2 0.0 3.8 0.0 0.3 24.0 42.0 4.4 33.3 39.8 21.5 71.5 20.9 59.7 63.9 ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 29.0;intestine: 45.4;seminal vesicle: 70.7" "Group enriched" "Detected in some" 18 "HEL: 5.0;Hep G2: 16.6;HMC-1: 7.4" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 74 "basophil: 18.2" "Lineage enriched" "Detected in single" 74 "granulocytes: 18.2" "Low region specificity" "Detected in some" HPA043772 Enhanced "Secreted - unknown location" 480000 "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavourable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" 0.8 7.9 0.5 2.0 0.5 0.0 4.0 2.1 0.4 19.0 18.5 0.2 29.0 9.3 6.2 7.2 0.5 2.3 1.8 0.2 0.4 0.7 11.9 2.7 1.7 0.2 0.5 0.2 0.9 0.2 0.0 0.5 0.4 0.2 3.7 4.8 0.6 14.9 70.7 0.2 0.8 45.4 1.9 0.4 0.5 0.7 1.0 0.2 4.1 0.5 1.2 0.5 0.9 1.2 0.0 0.0 18.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 5.0 0.0 16.6 0.0 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.5 2.1 0.4 0.4 0.7 0.5 0.2 0.2 0.2 ENPP4 "AP3Aase, KIAA0879, NPP4" ENSG00000001561 "Ectonucleotide pyrophosphatase/phosphodiesterase 4" Q9Y6X5 6 46129993-46146699 "Enzymes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 12.0;SCLC-21H: 12.3;U-266/70: 14.9;U-266/84: 17.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016594 Approved "HPA016594: AB_1848171" "unprognostic (9.87e-2)" "unprognostic (1.74e-1)" "unprognostic (2.75e-2)" "unprognostic (2.01e-1)" "unprognostic (2.92e-1)" "unprognostic (1.90e-1)" "unprognostic (8.13e-2)" "unprognostic (5.51e-3)" "unprognostic (1.98e-1)" "unprognostic (1.26e-1)" "unprognostic (8.51e-2)" "unprognostic (4.36e-1)" "prognostic favourable (6.95e-7)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.62e-2)" "unprognostic (2.56e-1)" 12.7 12.5 14.8 6.2 21.9 30.2 14.3 10.1 20.6 9.8 10.5 19.3 31.9 9.5 3.8 10.9 4.8 9.9 7.3 12.9 19.8 15.7 16.8 9.0 17.9 6.9 30.8 15.6 3.4 10.4 22.2 14.1 3.2 23.9 15.0 11.6 7.1 17.5 30.8 20.9 3.6 8.7 8.6 43.2 11.5 12.3 7.1 22.2 4.8 11.3 7.3 5.6 8.0 5.9 3.1 1.8 0.9 2.7 4.6 11.0 3.1 0.0 0.7 0.5 1.0 0.0 0.0 0.0 1.1 1.1 2.7 0.2 1.2 9.0 10.0 8.7 1.4 0.1 2.7 0.4 0.5 12.0 7.5 5.5 0.0 0.0 0.4 6.8 10.2 1.4 0.0 0.0 0.0 0.9 0.0 0.0 1.0 1.1 5.0 0.6 1.8 0.3 3.8 1.8 3.7 5.7 1.1 12.3 0.0 0.0 1.9 0.0 5.1 2.8 0.0 0.0 4.7 0.2 7.4 14.9 17.0 3.4 7.1 0.0 0.9 0.0 0.4 0.9 11.0 1.3 6.4 3.1 4.1 7.9 1.7 1.5 4.0 7.0 0.3 4.6 2.7 1.8 1.4 3.1 14.8 21.9 10.1 20.6 19.8 15.7 30.8 15.6 23.9 22.2 ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.2;kidney: 30.8" "Group enriched" "Detected in some" 7 "HDLM-2: 1.8;Karpas-707: 6.3;SH-SY5Y: 7.1;U-266/70: 5.8;U-266/84: 3.1" "Cancer enriched" "Detected in some" 5 "glioma: 3.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042740 Approved Approved "Golgi apparatus" "Intracellular and membrane" 68000 "Golgi apparatus" "HPA042740: AB_10793984" "unprognostic (4.81e-4)" "unprognostic (1.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.56e-1)" "unprognostic (6.69e-3)" "unprognostic (3.07e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.60e-3)" "unprognostic (3.04e-2)" "unprognostic (1.72e-1)" "unprognostic (2.98e-2)" "unprognostic (2.82e-1)" "unprognostic (3.93e-3)" "unprognostic (2.01e-1)" 0.5 0.6 2.0 1.1 8.0 1.1 1.0 1.7 6.7 0.5 1.3 35.2 0.4 2.0 0.5 6.9 1.3 0.5 0.8 0.5 5.4 3.5 30.8 0.4 0.6 1.1 26.1 3.3 13.7 0.3 0.3 4.1 0.4 19.5 2.7 1.3 7.7 0.9 6.9 0.4 0.5 2.5 0.4 28.2 1.2 1.5 2.7 14.0 0.0 0.5 0.0 3.1 0.9 0.7 0.9 0.8 2.2 0.9 1.5 0.6 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.7 0.3 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.4 0.0 0.2 7.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 5.8 3.1 0.1 0.1 0.1 0.0 2.2 0.9 0.6 0.5 0.5 0.6 0.7 0.4 0.3 0.1 0.9 0.4 0.5 1.7 1.5 0.3 0.8 0.5 0.1 2.0 8.0 1.7 6.7 5.4 3.5 26.1 3.3 19.5 14.0 ENPP7 "alk-SMase, NPP7" ENSG00000182156 "Ectonucleotide pyrophosphatase/phosphodiesterase 7" Q6UWV6 17 79730919-79742222 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 71.1" "Group enriched" "Detected in some" 5 "Hep G2: 2.8;Karpas-707: 5.1;U-266/70: 6.9" "Cancer enriched" "Detected in some" 6 "liver cancer: 6.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "memory B-cell: 1.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024603 Approved "Intracellular and membrane" 440000 "HPA024603: AB_1848174" "unprognostic (4.00e-2)" "unprognostic (1.16e-2)" "unprognostic (6.49e-2)" "unprognostic (4.83e-2)" "unprognostic (1.55e-1)" "unprognostic (2.65e-2)" "unprognostic (1.24e-1)" "unprognostic (1.01e-1)" "unprognostic (8.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (5.21e-2)" "unprognostic (1.25e-1)" "unprognostic (1.80e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.9 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.7 1.3 0.1 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ENTPD1 "ATPDase, CD39, NTPDase-1, SPG64" ENSG00000138185 "Ectonucleoside triphosphate diphosphohydrolase 1" P49961 10 95711779-95869695 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Hydrolase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 59.4" "Group enriched" "Detected in some" 7 "HDLM-2: 56.0;Karpas-707: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 37.4" "Low lineage specificity" "Detected in many" "CAB002494, HPA014067" Enhanced Uncertain Microtubules Microtubules "CAB002494: AB_563557, HPA014067: AB_1848178" "unprognostic (1.14e-1)" "unprognostic (1.01e-2)" "unprognostic (3.11e-1)" "unprognostic (5.67e-2)" "unprognostic (9.68e-3)" "unprognostic (3.45e-3)" "unprognostic (6.31e-2)" "unprognostic (5.26e-3)" "unprognostic (2.73e-1)" "unprognostic (1.28e-2)" "unprognostic (6.40e-2)" "unprognostic (1.41e-1)" "prognostic unfavourable (5.33e-5)" "unprognostic (9.79e-2)" "unprognostic (2.30e-1)" "prognostic favourable (7.89e-4)" "unprognostic (5.09e-2)" 10.4 7.5 7.4 16.2 8.4 15.6 8.8 7.6 6.9 18.9 12.7 13.1 8.7 5.8 59.4 12.8 13.2 15.6 22.2 6.8 7.4 7.4 6.2 3.9 14.8 14.5 8.5 4.9 10.3 2.8 3.0 4.3 24.0 9.9 14.7 9.1 10.8 6.7 12.7 3.3 5.5 12.2 37.2 17.9 25.3 7.5 5.4 7.2 3.5 13.4 12.5 21.1 25.2 12.4 6.0 11.8 37.4 15.2 0.5 5.1 4.6 0.1 0.3 0.9 0.8 0.0 0.0 0.5 0.5 0.4 0.0 0.0 0.5 0.1 1.0 0.6 0.0 0.2 0.0 0.0 0.0 56.0 0.7 0.6 0.4 0.7 0.0 1.5 0.2 0.0 0.0 0.2 0.0 7.4 0.6 46.0 0.0 0.6 0.4 1.5 0.6 0.2 2.3 0.3 0.7 0.5 0.2 0.7 1.0 0.3 1.1 0.7 0.5 1.6 0.8 0.4 0.2 0.6 0.6 6.6 0.9 0.0 0.6 3.1 0.2 0.1 15.2 37.4 0.1 10.7 0.3 6.0 0.6 0.3 11.8 4.6 0.1 0.1 26.7 0.5 2.4 0.7 5.1 4.6 7.4 8.4 7.6 6.9 7.4 7.4 8.5 4.9 9.9 7.2 ENTPD3 "CD39L3, HB6, NTPDase-3" ENSG00000168032 "Ectonucleoside triphosphate diphosphohydrolase 3" O75355 3 40387156-40428619 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 26.2;pancreas: 37.3" "Cell line enhanced" "Detected in some" "HBEC3-KT: 12.4;hTCEpi: 8.4;RT4: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "plasmacytoid DC: 7.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (1.00e-1)" "unprognostic (1.54e-2)" "unprognostic (2.75e-2)" "unprognostic (9.84e-3)" "unprognostic (2.27e-2)" "unprognostic (2.04e-1)" "unprognostic (1.80e-1)" "unprognostic (1.18e-2)" "unprognostic (8.40e-2)" "unprognostic (9.88e-3)" "unprognostic (4.72e-2)" "unprognostic (2.08e-1)" "unprognostic (3.25e-1)" "unprognostic (6.53e-2)" "unprognostic (5.99e-2)" "unprognostic (1.68e-1)" "unprognostic (1.23e-1)" 4.6 2.2 5.7 1.7 25.9 0.5 2.1 5.4 15.8 26.2 3.3 0.6 1.9 1.7 4.0 4.4 7.5 1.3 3.6 1.4 4.9 6.3 3.6 0.5 4.8 0.9 4.0 6.3 2.6 37.3 1.7 4.2 2.9 14.5 5.3 3.6 2.8 21.2 5.1 1.7 3.2 1.6 2.5 1.7 5.1 8.8 1.3 4.8 0.0 7.0 5.6 4.8 13.7 2.9 0.5 7.4 1.4 0.3 0.9 0.8 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 3.7 0.0 12.4 0.3 0.7 0.4 0.7 0.5 0.2 0.0 0.0 0.0 0.1 8.4 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.1 0.1 1.1 0.1 0.0 0.3 1.5 17.9 1.9 0.4 0.8 1.4 0.3 0.6 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.3 0.0 1.0 0.1 0.1 1.4 0.2 0.0 0.2 0.3 0.8 0.3 0.2 0.3 0.0 0.5 0.6 0.6 0.0 0.9 0.2 7.4 0.6 0.1 5.7 25.9 5.4 15.8 4.9 6.3 4.0 6.3 14.5 4.8 ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA017655 Supported Supported Vesicles 28000 Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" 16.3 11.5 15.0 21.9 19.8 25.7 15.3 20.3 27.4 15.2 18.5 14.7 15.7 17.0 18.8 17.9 13.3 12.7 14.4 21.0 14.5 12.8 13.0 14.4 19.9 26.0 16.2 12.2 14.7 26.5 30.4 25.2 19.3 20.6 17.6 20.2 18.0 19.5 13.7 14.9 12.2 26.1 16.1 14.5 26.9 19.1 18.7 15.8 17.0 15.8 9.3 30.7 16.7 16.7 9.7 8.0 15.9 9.5 4.4 10.7 6.8 9.9 13.7 17.2 11.9 15.1 19.2 17.6 15.9 15.2 10.8 16.9 19.6 13.2 16.8 11.5 16.0 12.1 7.8 14.4 20.8 4.0 5.4 8.9 8.5 6.8 12.3 4.7 17.7 11.7 17.5 14.4 15.4 15.4 6.1 15.5 18.2 4.5 6.8 5.7 10.0 5.0 6.8 17.2 5.1 13.8 11.8 13.7 13.1 6.0 8.7 11.7 6.4 6.7 19.1 19.7 19.4 22.0 11.7 12.4 5.2 22.0 26.3 5.6 19.7 14.9 6.0 13.7 8.5 9.5 10.0 9.7 8.3 9.1 8.0 6.7 10.7 8.3 15.9 4.4 6.9 7.3 6.5 6.8 15.0 19.8 20.3 27.4 14.5 12.8 16.2 12.2 20.6 15.8 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5" O75356 14 73958010-74019399 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 52.0;kidney: 43.1;liver: 71.4" "Cell line enhanced" "Detected in all" "RT4: 33.8" "Cancer enhanced" "Detected in all" "prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 15.0;eosinophil: 8.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced Approved Cytosol "Secreted to blood" 5000000 Cytosol "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favourable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 3.0 3.6 2.8 9.4 3.8 1.7 3.5 3.0 4.0 2.4 25.8 5.8 3.1 19.3 3.0 2.7 4.5 2.4 6.6 2.6 2.8 2.3 43.1 71.4 2.3 1.3 3.5 2.3 3.3 5.9 1.8 2.7 2.2 5.5 10.2 29.6 3.2 4.7 1.5 3.8 2.7 52.0 3.9 5.5 3.2 11.8 4.5 2.5 2.1 2.7 3.0 3.3 9.5 3.0 1.6 1.6 15.0 2.1 0.6 2.5 1.2 5.3 4.3 4.9 9.1 9.8 9.3 5.7 5.6 4.6 3.7 4.3 3.3 6.4 6.0 2.8 7.6 6.3 4.9 8.1 4.2 5.1 2.3 4.5 3.2 17.8 9.5 2.7 5.3 7.6 8.2 5.3 11.0 7.5 5.0 9.3 5.5 7.6 3.0 3.3 1.5 9.4 3.5 4.7 2.9 6.6 33.8 3.5 3.7 9.5 7.5 5.4 10.9 2.4 6.2 7.6 7.9 4.5 4.1 6.0 9.4 4.9 4.8 5.0 6.8 15.0 1.2 8.3 2.5 2.1 1.3 1.3 1.3 1.7 1.6 1.6 2.1 2.1 0.2 0.6 1.3 0.8 1.4 1.2 2.8 3.8 3.0 4.0 2.8 2.3 3.5 2.3 5.5 2.5 ENTPD6 "CD39L2, dJ738P15.3, IL6ST2, NTPDase-6" ENSG00000197586 "Ectonucleoside triphosphate diphosphohydrolase 6 (putative)" O75354 20 25195693-25226729 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015491, HPA069555" Approved Supported "Golgi apparatus" "Secreted to blood" 18000 "Golgi apparatus" "HPA015491: , HPA069555: " "unprognostic (3.24e-1)" "unprognostic (1.27e-2)" "unprognostic (5.91e-2)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (4.44e-1)" "unprognostic (2.10e-3)" "unprognostic (7.41e-3)" "unprognostic (2.74e-3)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (8.14e-3)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (4.86e-2)" "unprognostic (4.48e-2)" 12.7 19.7 21.8 11.3 46.5 6.7 12.8 33.1 49.1 9.8 31.3 12.1 12.8 31.6 9.4 10.1 9.0 12.5 18.3 27.5 24.9 25.0 13.4 12.9 11.0 7.4 15.1 29.2 16.1 25.6 11.7 20.5 13.2 15.4 25.5 24.5 9.0 36.8 9.7 15.1 6.8 32.2 9.9 8.2 8.3 24.7 16.1 10.5 9.4 10.4 6.1 8.3 10.2 7.1 7.2 17.1 3.0 16.0 8.8 17.9 12.9 20.4 32.4 8.9 17.0 11.2 14.1 19.1 16.8 12.2 14.6 13.5 17.3 15.8 12.4 25.4 16.2 26.8 10.8 25.6 9.7 7.6 9.7 10.1 4.9 39.1 16.8 13.4 15.5 13.2 14.3 18.4 14.0 11.7 13.1 21.7 10.8 19.6 12.5 8.3 5.6 25.4 7.1 27.8 28.4 18.3 12.8 14.2 7.4 4.6 28.5 75.7 20.8 11.3 12.7 17.1 17.8 14.0 19.8 13.6 11.0 5.4 12.2 8.9 32.0 0.0 16.0 3.0 12.7 10.7 17.9 6.1 11.4 10.4 17.1 7.2 12.2 10.6 0.7 8.8 4.8 12.0 10.6 12.9 21.8 46.5 33.1 49.1 24.9 25.0 15.1 29.2 15.4 10.5 ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 48.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.0;RPMI-8226: 8.7;T-47d: 4.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Nucleoplasm, Cytosol" Vesicles "HPA021509: AB_1848185" "unprognostic (3.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.70e-2)" "unprognostic (3.87e-2)" "unprognostic (8.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-2)" "unprognostic (1.08e-5)" "prognostic favourable (7.17e-4)" "unprognostic (2.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" 0.4 0.0 0.4 2.6 0.4 0.0 0.4 0.4 0.4 0.4 19.2 0.4 0.4 18.5 0.4 0.4 0.4 0.3 2.2 0.4 0.5 0.0 2.1 9.8 0.8 0.4 0.4 0.4 0.4 1.8 0.0 4.2 0.5 0.4 0.4 7.5 0.8 4.1 0.4 0.4 0.0 48.1 0.4 0.4 0.4 6.1 0.4 0.4 0.6 0.4 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.0 9.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 1.5 0.2 0.0 0.6 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 1.6 0.0 0.2 0.1 0.4 0.0 0.0 8.7 1.4 0.0 0.3 0.9 0.2 0.0 0.1 4.7 0.2 0.1 0.0 2.4 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.5 0.0 0.4 0.4 0.4 0.4 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810092-225845563 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.4;liver: 265.0" "Cell line enhanced" "Detected in many" "ASC diff: 153.8;SiHa: 73.1" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 6.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced 83000 "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favourable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favourable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 39.5 156.4 16.8 5.7 20.1 3.4 31.3 8.3 25.1 31.3 12.6 28.7 15.3 16.6 21.8 15.7 24.9 26.2 17.8 11.5 16.3 11.2 36.8 265.0 24.1 6.9 17.1 14.5 45.6 85.0 39.5 14.0 5.4 23.6 25.9 8.4 27.3 26.3 21.3 16.4 8.8 9.6 18.6 10.7 8.3 12.1 22.7 12.6 3.6 24.9 15.6 14.9 20.9 32.3 0.5 2.2 0.5 6.6 1.4 1.3 2.3 4.4 42.3 1.6 15.6 153.8 16.0 3.4 5.1 6.4 3.7 5.2 8.7 45.0 0.1 19.3 19.2 4.9 4.6 2.4 1.5 0.9 8.0 3.1 17.9 48.8 16.7 1.9 1.8 15.0 5.6 10.5 1.0 2.7 2.2 3.9 6.6 5.1 1.9 3.6 9.1 11.9 4.1 2.0 12.8 11.1 27.9 14.6 1.9 73.1 26.2 6.7 19.4 5.7 8.1 6.3 5.1 8.5 8.1 1.3 6.7 0.5 9.5 2.1 8.3 0.0 6.6 0.2 0.5 1.9 0.9 0.3 0.9 0.5 1.5 0.5 1.3 1.0 0.5 1.4 0.8 2.2 0.7 2.3 16.8 20.1 8.3 25.1 16.3 11.2 17.1 14.5 23.6 12.6 EPHX2 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490779-27545564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 83.9;liver: 87.6" "Cell line enhanced" "Detected in many" "K-562: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 39.2" "Lineage enriched" "Detected in many" 24 "T-cells: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Approved Enhanced Cytosol 720000 Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favourable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favourable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 4.8 25.1 4.8 14.3 6.0 0.4 8.3 5.6 3.3 7.6 56.2 6.1 21.8 29.8 10.3 15.1 15.2 11.3 9.4 7.8 4.1 4.8 44.2 87.6 4.6 5.0 5.8 3.2 11.4 25.3 11.6 14.6 2.9 10.5 17.9 15.6 13.3 18.0 22.7 8.5 11.5 83.9 13.1 4.5 3.5 6.7 5.4 3.9 45.7 7.5 13.2 11.7 7.0 7.4 1.6 0.0 0.0 0.0 1.4 39.2 7.6 8.4 5.7 3.6 4.7 0.2 0.0 2.7 0.7 0.5 0.4 0.1 4.5 5.8 0.0 3.4 2.1 6.1 0.6 1.4 0.3 0.0 2.7 12.5 0.6 13.7 2.0 0.0 2.6 5.1 6.2 0.0 0.7 0.3 28.2 0.1 0.0 2.6 8.1 0.3 5.8 9.9 0.0 0.0 0.2 5.1 1.2 3.0 9.4 6.9 8.2 8.2 12.5 2.3 0.1 0.0 2.3 1.0 0.1 7.3 5.4 0.1 0.2 0.0 0.1 0.0 0.0 0.0 2.9 0.0 4.0 1.6 12.5 4.5 0.0 0.9 39.2 18.0 0.0 1.4 0.0 0.0 9.4 7.6 4.8 6.0 5.6 3.3 4.1 4.8 5.8 3.2 10.5 3.9 EPHX3 "ABHD9, FLJ22408" ENSG00000105131 "Epoxide hydrolase 3" Q9H6B9 19 15226919-15233435 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.8;lymphoid tissue: 29.6;skin 1: 33.1;tongue: 39.6" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;NTERA-2: 5.9;SCLC-21H: 2.6" "Cancer enhanced" "Detected in many" "cervical cancer: 30.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "intermediate monocyte: 4.2;non-classical monocyte: 4.9" "Group enriched" "Detected in many" 18 "dendritic cells: 2.8;monocytes: 4.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012842 Uncertain Approved Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA012842: AB_10601648" "unprognostic (1.39e-1)" "unprognostic (1.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "prognostic favourable (2.27e-5)" "unprognostic (8.83e-3)" "unprognostic (1.50e-1)" "unprognostic (3.90e-1)" "unprognostic (4.36e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-1)" "unprognostic (3.68e-2)" "unprognostic (1.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.01e-2)" 0.2 0.1 0.1 0.2 0.3 0.1 1.0 0.1 0.3 12.5 0.2 0.2 0.4 0.1 0.9 0.3 34.8 1.1 1.7 0.1 0.5 0.1 1.6 0.2 1.6 0.0 0.2 0.0 0.6 0.0 2.2 2.4 0.2 0.4 1.5 0.1 0.6 3.4 0.6 0.2 33.1 0.2 0.2 0.2 1.2 0.5 2.7 0.2 2.4 0.2 39.6 29.6 2.8 13.6 0.0 2.8 0.2 4.9 0.0 0.0 0.5 0.2 0.6 1.0 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.7 0.8 0.5 6.3 0.2 0.3 0.2 0.1 0.0 0.2 0.1 0.3 0.1 0.0 0.5 0.0 0.5 0.0 0.3 0.6 0.0 0.0 0.3 0.4 0.0 1.0 0.1 0.8 5.9 0.8 0.0 0.0 0.1 0.2 1.3 2.6 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.4 0.8 0.1 0.3 0.1 0.6 0.8 0.1 0.2 0.2 0.0 1.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 4.9 2.8 0.0 0.5 0.1 0.3 0.1 0.3 0.5 0.1 0.2 0.0 0.4 0.2 EPM2A "LD, LDE" ENSG00000112425 "EPM2A, laforin glucan phosphatase" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation, Epilepsy, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.9" "Cell line enhanced" "Detected in many" "Daudi: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 5.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Enhanced Nucleoplasm Nucleoplasm "HPA053643: , HPA055468: " "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-3)" "unprognostic (2.92e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.52e-4)" "unprognostic (2.28e-1)" "prognostic favourable (4.08e-7)" "unprognostic (4.12e-4)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" 5.4 6.0 8.8 1.9 9.0 2.2 3.6 4.0 8.9 3.9 11.1 8.6 2.5 3.4 4.8 4.8 8.9 4.3 3.9 19.4 9.6 8.7 8.0 5.7 3.5 3.4 11.9 5.5 5.9 2.9 5.5 3.3 2.0 9.6 6.2 3.4 5.6 3.1 9.2 60.9 2.4 3.3 13.9 13.6 2.5 4.6 3.3 7.1 3.7 4.2 15.7 2.9 10.4 6.0 1.4 1.0 0.3 1.4 5.4 2.4 1.0 1.1 1.7 3.2 6.2 8.0 2.5 1.4 2.9 3.4 2.7 3.4 1.5 1.6 19.9 2.5 3.5 1.7 1.2 1.2 2.5 7.7 1.6 3.2 2.3 2.5 4.9 11.0 2.0 2.0 6.6 1.6 0.5 1.9 1.4 5.1 3.4 2.6 7.3 2.4 3.3 1.7 4.2 2.9 5.8 2.4 1.6 6.0 5.9 5.2 3.1 6.8 1.8 6.4 4.2 2.8 1.3 2.6 2.3 3.7 3.7 8.0 2.4 2.7 4.3 0.0 0.1 0.1 0.4 1.4 1.1 1.3 1.1 0.9 1.0 1.4 1.2 2.4 0.3 5.4 0.3 0.9 0.2 1.0 8.8 9.0 4.0 8.9 9.6 8.7 11.9 5.5 9.6 7.1 ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "CAB005375: AB_2100152, HPA038057: , HPA069266: " "unprognostic (1.10e-1)" "unprognostic (5.48e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-3)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (1.06e-1)" "prognostic favourable (3.26e-4)" "unprognostic (3.36e-2)" "unprognostic (2.44e-3)" "unprognostic (1.94e-1)" "unprognostic (5.47e-1)" "unprognostic (8.99e-2)" "unprognostic (3.45e-2)" 7.4 15.6 11.4 10.6 17.7 6.7 7.1 9.5 23.8 9.4 8.1 11.7 7.8 7.9 11.7 6.0 6.7 10.0 10.1 7.9 9.4 9.1 8.7 13.2 6.5 9.9 8.2 10.5 9.5 13.1 12.9 10.9 7.2 14.0 8.2 6.4 12.5 9.5 11.8 15.9 10.7 7.1 11.2 5.3 9.7 8.3 17.2 7.8 10.8 10.2 5.1 8.3 9.3 6.6 7.8 17.2 5.0 13.9 11.3 9.8 8.7 12.3 6.0 12.6 17.7 7.5 8.9 6.7 17.6 12.1 22.8 17.5 14.0 8.5 4.4 10.1 17.1 6.4 8.8 14.8 8.7 10.6 14.5 7.5 11.5 14.7 15.9 11.9 13.3 10.2 2.3 26.0 14.8 13.2 18.2 5.0 15.7 6.0 7.0 7.9 5.8 10.6 13.5 8.9 3.7 6.5 10.9 7.4 8.0 15.6 11.1 6.2 10.5 15.8 17.1 21.8 11.9 9.2 39.1 11.6 6.7 6.4 6.4 7.3 9.6 0.0 13.3 5.0 7.7 13.9 9.8 7.8 7.4 7.4 17.2 5.8 7.1 7.4 0.4 11.3 10.9 8.3 7.4 8.7 11.4 17.7 9.5 23.8 9.4 9.1 8.2 10.5 14.0 7.8 ERCC3 "BTF2, GTF2H, RAD25, TFIIH, XPB" ENSG00000163161 "ERCC excision repair 3, TFIIH core complex helicase subunit" P19447 2 127257290-127294176 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037153, HPA046077" Approved Enhanced Nucleoplasm Nucleoplasm "CAB037153: AB_796181, HPA046077: " "unprognostic (2.31e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-3)" "unprognostic (1.05e-1)" "unprognostic (8.85e-2)" "prognostic unfavourable (1.62e-7)" "unprognostic (2.74e-1)" "unprognostic (9.13e-3)" "unprognostic (9.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.46e-2)" "prognostic unfavourable (4.30e-6)" "unprognostic (3.71e-1)" "unprognostic (8.50e-2)" "unprognostic (5.73e-2)" "unprognostic (3.92e-2)" 17.4 20.0 26.1 23.8 28.9 20.5 21.0 35.9 32.0 22.1 19.4 19.7 17.1 11.5 21.6 15.7 19.1 23.6 20.4 20.4 23.2 18.8 17.5 17.4 19.4 23.1 19.7 25.8 23.3 22.4 32.0 26.4 16.3 21.5 20.1 17.1 18.3 18.0 21.8 30.1 19.7 17.3 26.1 16.0 24.5 17.4 39.5 20.1 24.1 19.3 15.8 25.9 22.4 20.8 11.8 13.9 7.2 9.7 18.8 16.2 11.7 21.8 15.1 18.6 19.7 20.8 14.2 23.1 20.1 26.2 32.6 31.6 22.9 16.0 16.6 16.7 18.3 19.6 28.4 21.2 28.4 25.9 25.4 20.8 18.4 24.2 15.4 18.1 22.7 14.7 19.9 37.7 16.1 20.9 20.2 10.9 20.5 21.6 25.7 19.5 27.1 23.5 21.2 21.4 13.7 18.2 20.4 22.6 24.4 17.2 26.2 26.3 14.1 20.8 16.6 19.6 22.5 17.8 23.9 19.5 38.1 26.0 17.3 8.7 20.9 6.6 9.5 7.2 16.0 9.7 16.2 11.5 11.8 13.5 13.9 11.8 15.8 10.9 3.1 18.8 7.9 11.3 16.1 11.7 26.1 28.9 35.9 32.0 23.2 18.8 19.7 25.8 21.5 20.1 ERCC6L "FLJ20105, PICH, RAD26L" ENSG00000186871 "ERCC excision repair 6 like, spindle assembly checkpoint helicase" Q2NKX8 X 72204657-72239047 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "NK-cell: 5.3" "Lineage enriched" "Detected in many" 5 "NK-cells: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050492 Approved Supported Nucleoplasm,Centrosome,Cytosol Centrosome "Nucleoplasm, Cytosol" "HPA050492: " "prognostic unfavourable (1.80e-4)" "unprognostic (2.93e-1)" "unprognostic (1.95e-2)" "unprognostic (5.76e-3)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (9.23e-6)" "unprognostic (8.63e-3)" "unprognostic (1.57e-2)" "unprognostic (1.99e-2)" "unprognostic (3.68e-5)" "unprognostic (4.61e-2)" "unprognostic (0.00e+0)" "unprognostic (2.97e-3)" "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (6.41e-2)" 0.4 0.5 0.2 3.1 0.2 6.0 3.0 0.9 0.8 1.5 2.2 0.2 0.2 1.5 0.9 0.8 4.6 0.6 1.0 0.2 0.2 0.3 0.5 0.5 0.8 4.7 0.7 0.2 1.2 0.5 0.0 0.6 0.9 0.9 0.7 2.5 0.2 1.1 0.2 2.6 1.3 2.1 0.5 1.3 4.0 1.5 2.0 0.2 13.1 0.5 2.8 5.6 0.7 1.6 0.5 0.3 0.5 0.2 5.3 1.1 0.4 10.9 9.6 8.9 5.6 0.6 1.1 4.9 11.8 5.4 10.4 10.9 7.8 6.9 17.8 4.5 4.2 9.1 16.6 8.8 18.5 10.1 12.1 6.1 3.3 4.6 0.0 11.9 8.6 0.1 0.5 14.4 2.7 5.7 8.0 4.4 10.5 8.6 11.3 7.0 16.1 14.9 9.5 15.9 3.1 2.6 6.8 7.3 5.2 8.7 5.9 2.2 4.5 2.6 3.5 7.0 11.3 13.2 7.7 3.4 5.3 15.3 4.9 8.3 7.0 0.0 0.2 0.5 0.1 0.1 0.6 0.2 0.5 0.1 0.1 0.5 0.4 1.1 0.3 5.3 0.2 0.3 1.1 0.4 0.2 0.2 0.9 0.8 0.2 0.3 0.7 0.2 0.9 0.2 ESD ENSG00000139684 "Esterase D" P10768 13 46771256-46797232 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039700 Approved Approved "Golgi apparatus,Cytosol" 16000000 "Golgi apparatus" Cytosol "HPA039700: AB_10697553" "unprognostic (3.05e-1)" "prognostic unfavourable (5.01e-4)" "unprognostic (7.66e-2)" "unprognostic (1.75e-1)" "unprognostic (1.63e-1)" "prognostic unfavourable (2.16e-4)" "unprognostic (1.73e-2)" "unprognostic (3.31e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (2.91e-2)" "unprognostic (2.71e-2)" "unprognostic (2.18e-1)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" 58.5 30.9 32.0 28.6 29.8 24.2 44.5 23.7 32.0 54.4 37.3 29.0 34.2 31.8 53.2 50.4 54.1 40.6 30.3 45.6 30.7 29.3 58.8 82.2 28.2 31.4 31.7 32.1 61.3 24.9 27.5 47.5 26.4 28.6 55.2 41.7 32.5 31.5 45.2 47.4 29.7 38.4 50.8 37.4 31.1 32.1 32.4 26.7 65.5 78.9 50.9 31.7 62.5 36.9 30.1 48.7 15.1 37.1 29.8 35.7 26.4 21.8 12.7 38.6 26.5 45.3 74.8 10.3 31.5 45.7 43.9 34.2 21.5 26.8 24.9 9.5 37.7 22.4 42.4 37.2 56.2 28.4 44.0 32.1 12.8 33.1 37.1 62.8 13.8 51.1 34.6 28.3 38.1 41.1 31.4 6.7 72.6 21.4 55.6 41.7 10.0 24.2 44.3 22.7 16.8 62.3 8.9 19.1 21.7 14.0 11.9 25.2 22.9 36.0 27.4 16.2 19.1 31.0 29.0 4.6 9.7 21.5 35.0 36.0 21.6 7.7 37.1 15.1 15.0 31.5 24.6 30.1 30.0 23.0 40.8 25.3 35.7 27.9 4.3 29.8 28.0 48.7 24.9 26.4 32.0 29.8 23.7 32.0 30.7 29.3 31.7 32.1 28.6 26.7 ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293643 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 17.9;lymphoid tissue: 30.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 5 "T-reg: 1.8" "Lineage enriched" "Detected in single" 5 "T-cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavourable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavourable (2.01e-5)" "prognostic unfavourable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favourable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" 0.7 0.4 0.2 7.1 0.4 7.2 0.3 0.2 0.5 3.9 2.3 0.4 0.8 4.2 0.6 0.7 17.9 0.2 0.5 1.0 1.1 0.1 1.0 0.9 0.7 4.1 0.2 0.2 0.3 0.2 0.0 0.2 3.0 0.6 0.4 1.5 0.6 2.6 0.2 0.2 2.7 4.4 0.5 0.2 3.0 0.8 10.9 0.3 30.3 0.3 2.5 7.8 0.7 6.2 0.0 0.0 0.4 0.1 0.0 1.8 0.0 12.4 12.7 13.7 11.2 0.3 1.2 8.4 8.2 4.2 14.1 9.0 6.9 11.0 22.5 4.6 3.3 10.4 15.8 4.8 7.4 7.0 16.0 15.1 11.5 5.3 0.0 9.4 12.5 0.4 0.3 8.2 4.0 7.2 20.2 20.4 4.2 13.0 14.8 8.1 11.0 6.9 13.9 14.6 9.3 2.0 5.2 9.8 7.6 6.9 10.2 5.3 16.8 6.3 3.3 7.1 13.8 6.0 11.2 15.1 14.0 15.2 4.1 8.9 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 1.8 0.0 0.2 0.4 0.2 0.5 1.1 0.1 0.2 0.2 0.6 0.3 EXD2 "C14orf114, EXDL2, FLJ10738" ENSG00000081177 "Exonuclease 3'-5' domain containing 2" Q9NVH0 14 69191511-69244020 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002906, HPA005848" Uncertain Approved "Intermediate filaments,Mitochondria" Mitochondria "Intermediate filaments" "HPA002906: AB_1078767, HPA005848: AB_1078768" "unprognostic (3.36e-2)" "unprognostic (1.61e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (2.85e-1)" "prognostic unfavourable (8.47e-4)" "unprognostic (9.91e-2)" "unprognostic (8.03e-2)" "unprognostic (2.46e-1)" "unprognostic (4.64e-2)" "unprognostic (8.97e-2)" "prognostic favourable (2.08e-9)" "unprognostic (1.16e-1)" "unprognostic (3.06e-2)" "unprognostic (8.75e-2)" "unprognostic (2.14e-2)" 8.1 7.7 14.3 5.0 19.0 2.3 10.6 20.4 20.1 15.8 8.8 21.7 10.2 7.2 14.4 13.6 10.7 14.5 8.6 8.9 13.8 12.0 11.5 6.0 9.0 4.0 13.7 13.3 12.4 24.9 21.9 13.2 8.0 13.9 11.4 10.0 9.6 17.0 12.1 10.3 7.0 6.8 11.0 20.7 5.8 8.7 20.0 12.6 5.0 12.4 5.2 5.9 10.5 7.9 4.1 7.4 10.9 3.4 3.6 6.0 3.1 18.8 8.9 6.9 10.1 4.2 5.1 8.7 9.4 8.0 8.8 11.7 7.5 13.3 0.0 7.0 9.8 10.7 7.6 9.5 10.0 4.7 9.1 5.5 3.3 4.4 16.6 4.0 5.3 10.3 15.8 9.0 5.9 12.4 3.4 7.3 8.3 9.5 2.3 6.1 7.4 8.9 0.0 6.6 6.6 13.0 7.0 13.4 12.0 7.0 14.8 6.9 19.7 3.5 9.8 8.2 5.8 6.6 4.8 5.6 7.4 0.0 0.0 4.4 6.1 10.9 3.4 2.9 3.3 1.9 6.0 4.1 3.5 3.3 7.4 2.4 4.2 6.0 0.4 3.6 1.7 5.8 2.4 3.1 14.3 19.0 20.4 20.1 13.8 12.0 13.7 13.3 13.9 12.6 EYA1 BOR ENSG00000104313 "EYA transcriptional coactivator and phosphatase 1" Q99502 8 71197433-71592025 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Deafness, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 45.5;pituitary gland: 30.8" "Cell line enhanced" "Detected in some" "AN3-CA: 16.4;RH-30: 12.7;SH-SY5Y: 31.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "NK-cell: 9.8" "Lineage enriched" "Detected in many" 4 "NK-cells: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028917 Supported "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA028917: " "unprognostic (3.74e-2)" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.72e-3)" "unprognostic (5.95e-2)" "unprognostic (9.17e-2)" "unprognostic (2.91e-4)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (1.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.13e-1)" "unprognostic (4.22e-12)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (3.81e-4)" "unprognostic (1.25e-2)" 1.0 1.1 2.8 0.6 16.8 0.5 0.6 0.2 6.8 4.0 0.6 1.9 0.0 0.7 0.6 2.2 1.0 2.5 0.8 4.6 2.8 2.2 0.6 0.5 1.0 0.6 2.9 2.8 0.8 0.6 45.5 30.8 0.6 4.2 12.4 0.7 15.3 1.2 4.6 3.2 0.6 0.7 3.9 0.4 0.7 0.9 1.3 5.1 4.4 0.9 2.9 0.6 3.5 5.7 0.8 1.9 1.8 2.3 9.8 2.3 0.2 0.1 0.0 3.7 16.4 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.9 0.0 0.0 2.7 0.0 1.2 0.0 0.0 0.3 0.0 3.6 0.0 0.0 0.1 0.0 0.0 1.2 0.6 0.0 0.0 0.0 1.2 0.9 0.0 12.7 5.4 0.0 0.0 1.3 31.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 1.2 1.8 0.3 0.6 0.9 0.9 1.9 0.8 0.7 1.9 0.7 0.8 1.3 1.4 1.6 9.8 2.3 1.9 2.3 0.2 2.8 16.8 0.2 2.8 2.8 2.2 2.9 2.8 4.2 5.1 EYA2 EAB1 ENSG00000064655 "EYA transcriptional coactivator and phosphatase 2" O00167 20 46894624-47188844 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 47.4" "Cell line enhanced" "Detected in some" "HBEC3-KT: 13.4;SCLC-21H: 20.4;U-266/70: 38.0;U-266/84: 46.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 69.3" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 16 "memory B-cell: 2.4" "Lineage enriched" "Detected in single" 16 "B-cells: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027024, HPA059291" Uncertain Supported Cytosol Cytosol "HPA027024: AB_1848334, HPA059291: " "unprognostic (1.08e-1)" "unprognostic (5.71e-3)" "unprognostic (4.03e-1)" "prognostic favourable (4.30e-5)" "unprognostic (3.32e-2)" "unprognostic (1.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.65e-1)" "unprognostic (7.06e-2)" "unprognostic (2.15e-1)" "unprognostic (2.78e-1)" "unprognostic (4.17e-3)" "unprognostic (1.56e-1)" 10.5 2.0 6.5 2.6 7.4 0.8 13.4 2.4 6.5 47.4 6.4 3.8 21.0 1.0 15.7 10.7 25.9 28.2 2.2 4.3 7.0 4.1 5.2 1.8 2.3 1.3 6.3 4.9 5.2 2.4 11.5 4.7 5.9 9.1 18.5 3.2 15.4 28.6 27.3 2.1 4.2 1.1 2.3 7.2 1.1 8.2 4.9 5.1 14.3 21.4 3.6 14.0 5.5 17.3 2.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.1 13.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.7 1.3 0.0 0.0 0.0 0.0 0.1 0.4 2.4 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 20.4 0.0 0.0 9.1 0.0 1.8 0.0 0.0 0.0 1.6 0.1 3.0 38.0 46.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 7.4 2.4 6.5 7.0 4.1 6.3 4.9 9.1 5.1 EYA3 DKFZp686C132 ENSG00000158161 "EYA transcriptional coactivator and phosphatase 3" Q99504 1 27970344-28088696 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052432, HPA062889" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA052432: , HPA062889: " "unprognostic (3.57e-1)" "unprognostic (2.61e-1)" "unprognostic (2.85e-1)" "unprognostic (8.74e-2)" "unprognostic (1.39e-1)" "prognostic favourable (5.11e-4)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (4.81e-2)" "unprognostic (1.00e-1)" "unprognostic (9.13e-2)" "unprognostic (8.98e-2)" "prognostic favourable (3.15e-6)" "unprognostic (5.17e-2)" "unprognostic (2.79e-1)" "unprognostic (7.60e-2)" "unprognostic (6.11e-2)" 12.8 10.0 14.9 24.0 12.9 8.6 13.3 21.9 13.8 14.7 10.2 14.4 12.8 10.7 14.4 12.4 19.4 11.8 8.1 11.7 10.6 11.8 21.6 11.3 12.5 15.6 11.1 8.8 12.4 12.9 20.9 29.2 13.8 12.9 11.8 11.7 16.4 11.8 13.1 14.5 16.3 12.2 10.5 10.1 14.2 10.0 20.6 13.7 17.4 17.3 12.2 25.0 10.7 13.8 8.6 12.4 10.5 11.2 10.4 12.1 2.6 10.4 4.4 8.9 6.6 10.4 8.1 5.0 7.6 7.3 9.0 8.9 4.3 6.4 16.5 8.5 5.2 10.2 16.4 6.3 10.7 8.7 9.2 18.8 8.9 7.6 6.2 18.1 17.3 4.9 5.7 9.9 6.7 11.5 17.2 6.5 8.0 4.5 11.5 12.1 18.7 5.8 8.8 16.4 10.5 10.6 5.8 10.3 5.7 8.2 5.2 7.3 4.2 4.8 11.0 10.8 5.8 9.9 6.3 9.6 9.6 15.3 7.8 17.6 4.7 7.5 11.2 10.5 12.1 10.4 10.8 8.6 9.5 8.7 12.4 7.6 8.3 9.4 9.7 10.4 8.3 7.7 8.2 2.6 14.9 12.9 21.9 13.8 10.6 11.8 11.1 8.8 12.9 13.7 EYA4 "CMD1J, DFNA10" ENSG00000112319 "EYA transcriptional coactivator and phosphatase 4" O95677 6 133240598-133532120 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Cardiomyopathy, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 65.6" "Cell line enhanced" "Detected in many" "A549: 12.6;HeLa: 35.3;RH-30: 12.0;U-87 MG: 12.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004805, HPA038771, HPA038772" Enhanced Approved Nucleoplasm Nucleoplasm "HPA004805: AB_10669750, HPA038771: AB_10671865, HPA038772: AB_10673119" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.27e-1)" "unprognostic (2.04e-9)" "unprognostic (1.64e-1)" "unprognostic (3.08e-2)" "unprognostic (3.44e-2)" "unprognostic (7.21e-2)" "unprognostic (9.07e-2)" "unprognostic (2.04e-2)" "unprognostic (2.80e-1)" "unprognostic (2.29e-1)" "unprognostic (8.27e-4)" "unprognostic (1.82e-3)" "unprognostic (6.67e-2)" "unprognostic (9.55e-2)" "unprognostic (2.51e-2)" 1.6 3.0 1.2 0.2 1.3 0.1 2.4 0.4 1.2 9.7 0.6 2.5 11.1 0.4 2.6 1.9 0.7 8.3 0.7 6.2 1.5 1.2 6.1 0.4 2.0 0.2 2.1 0.8 1.6 0.4 0.2 7.2 0.2 3.5 6.6 0.4 2.7 0.8 13.9 65.6 0.4 0.5 1.9 3.5 0.6 0.7 7.4 1.4 1.8 2.5 5.5 0.7 2.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 1.2 0.0 0.0 0.0 0.0 0.0 10.1 0.2 1.5 0.0 0.0 0.0 10.0 0.0 0.0 7.6 3.2 0.0 0.0 9.9 1.3 35.3 0.0 0.3 0.0 3.4 2.6 0.0 7.3 2.2 0.0 0.0 5.4 4.0 0.0 0.0 0.0 0.0 0.7 0.1 12.0 0.0 0.0 1.9 1.8 2.0 0.1 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 9.0 3.6 1.6 0.0 12.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.4 1.2 1.5 1.2 2.1 0.8 3.5 1.4 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122814-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 116.7" "Cell line enhanced" "Detected in some" "BJ: 8.3;CACO-2: 7.1;fHDF/TERT166: 7.4;Hep G2: 32.8;HHSteC: 6.8;SH-SY5Y: 16.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" 16000000000 "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favourable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavourable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 8.1 3.7 0.3 2.9 0.7 0.0 5.4 0.4 0.8 20.3 5.9 0.6 7.6 4.5 12.6 21.4 4.5 9.9 10.0 18.4 0.5 0.5 2.3 116.7 4.9 1.6 0.5 0.7 18.2 3.0 0.0 1.7 3.6 1.0 18.1 0.7 6.9 2.0 6.1 2.6 7.8 7.6 11.7 0.6 1.3 3.2 9.5 0.6 0.6 3.1 5.6 1.8 7.8 10.3 0.0 0.0 0.0 0.0 0.9 1.0 0.3 0.0 0.0 1.4 0.2 4.8 4.9 0.0 8.3 6.6 0.5 0.2 7.1 0.0 0.0 0.3 7.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 32.8 6.8 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.6 16.2 0.0 0.3 0.0 0.3 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.9 0.0 0.0 0.0 0.3 0.3 0.7 0.4 0.8 0.5 0.5 0.5 0.7 1.0 0.6 F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186265945-186288806 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 88.9" "Cell line enriched" "Detected in some" 11 "Hep G2: 13.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039808 Approved Vesicles "Secreted to blood" 4400000000 Vesicles "HPA039808: " "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favourable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 2.7 0.1 0.1 5.5 0.2 0.3 0.1 0.1 4.8 0.1 0.1 0.1 10.2 88.9 2.8 0.1 0.1 0.1 0.1 19.0 0.0 0.2 0.1 0.3 0.1 0.0 0.4 0.1 0.1 0.1 0.1 6.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.2 F12 ENSG00000131187 "Coagulation factor XII" P00748 5 177402140-177409576 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "liver: 180.1" "Cell line enhanced" "Detected in some" "HDLM-2: 8.6;MCF7: 10.9;PC-3: 8.1;SH-SY5Y: 5.5;U-937: 5.6" "Cancer enriched" "Detected in many" 21 "liver cancer: 171.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 2.5;eosinophil: 6.9" "Group enriched" "Detected in many" 5 "granulocytes: 6.9;monocytes: 2.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA003825 Approved "Secreted to blood" 1040000 6600000000 "HPA003825: AB_1078790" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (2.93e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "prognostic favourable (4.63e-5)" "unprognostic (6.97e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (4.41e-1)" "unprognostic (6.54e-2)" "prognostic unfavourable (7.09e-4)" "unprognostic (4.11e-2)" "unprognostic (3.69e-1)" "unprognostic (3.40e-6)" "unprognostic (6.48e-2)" 0.1 0.0 0.1 0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.2 180.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.5 1.0 6.9 2.5 0.7 0.3 1.0 0.8 2.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.3 1.3 0.0 0.4 0.0 1.4 0.7 0.4 0.0 8.6 1.8 1.3 0.3 0.9 0.2 0.7 3.0 0.2 1.3 0.1 0.4 0.2 0.4 3.2 0.0 10.9 0.1 2.6 0.0 8.1 0.6 0.2 1.8 1.1 0.0 2.5 5.5 0.3 1.0 0.7 0.4 0.0 0.0 0.2 1.1 0.0 0.3 0.5 0.0 0.1 0.1 5.6 0.6 0.0 2.5 6.9 0.3 0.1 0.2 0.5 0.3 0.2 0.1 0.2 0.0 0.1 0.9 0.7 0.9 1.0 0.0 1.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719180-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 593 "liver: 324.8" "Cell line enriched" "Detected in some" 21 "Hep G2: 76.5" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB016780, CAB018650, HPA051476, HPA054698" Enhanced "Secreted to blood" 107500000000 43000000000 "CAB016780: , CAB018650: AB_2246689, HPA051476: , HPA054698: " "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavourable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 324.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 76.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "liver: 68.0" "Group enriched" "Detected in some" 9 "CACO-2: 16.2;Hep G2: 10.1" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "gdT-cell: 1.7;MAIT T-cell: 1.2;memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 17 "T-cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" 3600000 1500000000 Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 68.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.4 0.1 0.1 0.1 0.1 0.1 0.1 F9 FIX ENSG00000101981 "Coagulation factor IX" P00740 X 139530758-139563458 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets, Hemophilia, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2334 "liver: 233.6" "Cell line enhanced" "Detected in some" "HL-60: 1.7;RH-30: 1.9;SiHa: 1.5;U-698: 1.1" "Cancer enriched" "Detected in single" 1354 "liver cancer: 67.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" 11000000000 "prognostic favourable (6.69e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 233.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 0.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394265-46413848 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 22.0;RT4: 23.7;SK-BR-3: 12.3" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 19.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol Cytosol "HPA007425: AB_1078820" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "prognostic favourable (1.51e-4)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "prognostic favourable (4.25e-5)" "prognostic favourable (3.63e-5)" "unprognostic (2.66e-1)" "unprognostic (9.97e-2)" "unprognostic (5.00e-3)" 6.1 7.7 11.2 2.5 22.0 7.9 7.9 20.4 21.9 6.9 15.0 40.7 10.1 18.0 3.1 8.2 4.9 10.6 4.6 2.9 14.7 11.7 12.0 18.3 6.7 2.1 19.1 19.3 2.7 18.2 15.1 10.6 3.5 17.6 33.3 12.8 7.4 12.8 8.6 7.1 10.1 17.8 2.3 23.6 2.0 14.3 30.9 18.8 5.6 24.9 3.5 3.5 5.7 4.2 0.1 6.0 19.1 4.7 0.3 0.4 0.9 2.7 0.7 0.4 0.5 0.7 0.5 22.0 0.6 0.3 0.3 0.5 4.0 6.6 0.1 2.3 0.4 9.3 0.4 1.3 0.1 1.2 3.1 0.0 0.1 1.9 0.4 0.8 1.6 0.4 6.3 0.2 0.8 0.0 0.1 0.5 0.0 5.9 0.4 1.2 1.8 0.2 0.5 0.2 0.1 5.2 23.7 2.8 2.1 3.2 12.3 0.1 8.5 8.2 0.0 0.0 0.3 0.6 0.4 1.2 0.5 0.3 0.1 7.5 0.2 0.0 4.7 19.1 0.3 1.2 0.1 0.0 0.3 0.1 5.7 0.1 0.4 0.4 0.2 0.3 0.6 6.0 0.1 0.9 11.2 22.0 20.4 21.9 14.7 11.7 19.1 19.3 17.6 18.8 FAAH2 "AMDD, FAAH-2, FLJ31204, RP11-479E16.1" ENSG00000165591 "Fatty acid amide hydrolase 2" Q6GMR7 X 57286706-57489196 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 43.6;pituitary gland: 42.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 10.5;HDLM-2: 9.4;RPMI-8226: 19.0;U-266/70: 15.9;U-266/84: 8.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 8 "cerebellum: 18.0" "Cell type enhanced" "Detected in many" "T-reg: 13.6" "Lineage enriched" "Detected in many" 8 "T-cells: 13.6" "unprognostic (1.37e-1)" "unprognostic (1.78e-2)" "unprognostic (7.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.02e-1)" "unprognostic (4.51e-2)" "unprognostic (7.93e-3)" "unprognostic (4.47e-2)" "unprognostic (1.94e-1)" "prognostic favourable (5.99e-4)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" "prognostic favourable (2.47e-13)" "unprognostic (9.16e-3)" "unprognostic (2.27e-1)" "prognostic favourable (2.66e-4)" "prognostic favourable (6.83e-5)" 1.0 1.4 1.0 6.8 1.5 0.0 6.7 18.0 1.0 3.5 3.9 0.2 3.8 2.6 1.4 4.7 5.5 5.8 2.4 0.6 1.2 2.3 9.7 20.1 3.5 5.7 1.1 0.5 1.9 43.6 12.7 42.8 1.4 1.8 9.3 3.6 3.8 9.1 5.3 0.3 10.0 6.4 0.6 1.1 2.3 4.1 0.6 0.3 8.5 15.3 2.7 11.0 3.0 3.6 1.8 1.0 0.3 0.0 0.7 13.6 1.5 2.4 0.2 0.0 0.1 0.1 0.1 2.3 0.0 0.0 0.0 0.0 1.7 10.5 0.1 3.0 0.0 0.4 0.8 1.8 0.0 9.4 5.1 0.3 2.4 0.7 0.0 1.1 0.0 0.0 3.2 0.0 0.0 0.0 1.2 4.7 0.0 1.0 0.5 0.0 1.8 0.0 0.0 1.8 19.0 6.2 3.3 1.8 0.1 0.1 3.0 0.0 2.9 0.0 0.0 0.0 0.2 0.0 0.1 15.9 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 4.7 1.8 7.7 3.2 0.0 0.6 7.5 0.9 0.3 0.7 0.0 1.0 13.6 1.5 1.0 1.5 18.0 1.0 1.2 2.3 1.1 0.5 1.8 0.3 FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 109.4" "Cell line enhanced" "Detected in many" "HHSteC: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041370, HPA044093" Enhanced Approved Cytosol 230000000 Cytosol "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavourable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" 32.1 17.8 4.6 6.1 3.6 4.7 22.8 2.3 3.3 4.7 8.6 3.1 8.3 4.1 5.1 14.8 4.4 6.8 7.1 6.8 4.1 2.8 18.9 109.4 7.9 6.2 4.0 2.1 7.2 6.5 4.8 4.4 2.3 3.5 4.9 3.4 2.4 5.3 5.4 7.7 2.4 7.6 4.4 5.9 6.0 3.3 9.7 3.0 2.3 4.2 4.9 3.9 4.1 6.1 0.1 16.0 16.9 11.7 3.6 5.8 6.1 4.4 7.5 3.1 3.8 14.5 14.8 7.6 5.7 13.1 6.0 5.2 4.5 8.2 0.0 9.4 12.0 6.6 11.0 13.6 5.9 2.8 6.2 38.1 4.4 23.3 75.2 18.0 21.1 25.6 8.5 5.2 9.4 8.4 15.9 8.1 11.3 6.7 4.9 9.0 2.2 8.6 2.7 4.4 28.5 17.5 5.4 0.1 1.9 6.4 17.7 17.8 13.5 12.3 29.3 11.1 7.0 5.9 9.6 7.4 15.2 3.0 23.1 42.2 6.2 16.9 11.7 1.9 5.8 4.9 1.5 0.1 1.6 3.9 16.0 0.0 2.0 1.8 0.7 3.6 4.8 1.2 1.5 6.1 4.6 3.6 2.3 3.3 4.1 2.8 4.0 2.1 3.5 3.0 FAHD1 "C16orf36, DKFZP566J2046" ENSG00000180185 "Fumarylacetoacetate hydrolase domain containing 1" Q6P587 16 1826941-1840207 "Enzymes, Predicted intracellular proteins" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025530, HPA043226, HPA043534" Enhanced Enhanced Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "CAB025530: , HPA043226: AB_2678370, HPA043534: AB_2678535" "unprognostic (3.71e-1)" "unprognostic (1.25e-2)" "prognostic favourable (8.27e-4)" "unprognostic (1.99e-1)" "unprognostic (6.74e-2)" "unprognostic (1.01e-3)" "unprognostic (2.89e-2)" "unprognostic (4.32e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "prognostic favourable (2.80e-14)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (3.31e-2)" 10.4 17.0 10.4 6.7 9.9 6.5 9.2 8.6 12.7 6.8 21.7 9.3 8.2 26.7 9.8 10.9 14.8 5.8 10.2 15.8 10.9 11.4 46.8 43.6 5.6 5.2 10.1 9.4 7.9 17.4 9.0 11.1 10.4 9.9 8.1 11.1 8.5 9.1 9.8 20.2 12.4 24.8 6.9 8.8 6.3 14.9 6.9 9.5 4.7 12.5 19.0 5.7 9.9 7.9 18.5 23.1 8.6 27.5 19.6 16.0 13.7 8.3 18.8 9.0 15.8 12.0 8.7 5.6 13.7 6.8 9.2 10.1 12.0 8.7 5.3 11.6 8.5 17.2 7.0 11.0 8.3 8.0 16.6 4.8 16.2 27.6 11.7 8.2 9.2 11.4 14.5 8.4 5.6 11.9 4.9 5.6 11.5 38.2 4.4 12.5 5.3 14.1 10.2 12.2 15.0 32.9 10.5 17.6 14.6 17.9 14.4 21.5 21.2 5.6 17.4 15.1 10.8 8.8 7.4 8.1 17.0 6.3 9.6 6.0 6.4 6.5 23.5 8.6 14.4 27.5 13.0 18.5 14.5 15.7 23.1 16.9 16.0 14.9 2.0 19.6 19.1 17.9 14.7 13.7 10.4 9.9 8.6 12.7 10.9 11.4 10.1 9.4 9.9 9.5 FAN1 "KIAA1018, MTMR15" ENSG00000198690 "FANCD2 and FANCI associated nuclease 1" Q9Y2M0 15 30903852-30943108 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048198 Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA048198: " "unprognostic (7.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-1)" "unprognostic (3.30e-2)" "unprognostic (6.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.97e-1)" "unprognostic (1.19e-1)" "unprognostic (5.94e-2)" "unprognostic (3.53e-2)" "unprognostic (3.53e-2)" "unprognostic (9.67e-2)" "prognostic favourable (1.42e-6)" "unprognostic (3.73e-1)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" "unprognostic (1.29e-1)" 5.9 8.9 11.6 6.9 17.4 6.3 12.7 19.6 18.4 15.0 11.4 17.7 11.9 4.6 11.6 22.9 6.5 8.5 8.5 13.0 12.6 11.0 14.7 14.4 6.9 5.5 18.5 11.8 12.5 18.2 7.2 17.0 10.6 15.4 16.4 9.7 8.6 17.3 8.3 16.8 9.3 6.7 11.5 13.0 7.3 8.5 9.4 15.0 5.1 14.3 6.3 5.8 9.0 9.1 4.0 3.6 0.6 1.7 4.5 5.4 1.6 6.4 11.0 3.6 2.0 13.0 11.6 2.4 4.5 1.9 4.8 5.1 7.5 3.3 1.5 8.1 4.9 13.0 6.1 9.5 4.7 5.1 2.9 1.1 11.2 1.3 5.6 0.9 6.1 3.5 7.0 2.9 7.7 2.3 5.5 10.1 7.8 1.4 10.0 4.4 2.8 2.5 8.5 11.9 2.8 7.1 5.1 8.3 5.8 9.9 6.8 3.5 6.1 7.6 8.3 15.1 3.6 4.2 5.8 13.9 9.7 1.7 6.6 4.8 1.3 0.1 0.8 0.6 3.7 1.3 4.7 2.8 3.5 1.7 2.7 4.0 5.4 2.8 0.3 4.5 1.7 3.6 3.2 1.6 11.6 17.4 19.6 18.4 12.6 11.0 18.5 11.8 15.4 15.0 FANCM "FAAP250, KIAA1596" ENSG00000187790 "Fanconi anemia complementation group M" Q8IYD8 14 45135940-45200890 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Disease mutation, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055144 Supported Nucleoplasm Nucleoplasm "HPA055144: " "unprognostic (8.40e-2)" "unprognostic (6.70e-2)" "unprognostic (3.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.15e-1)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (1.18e-1)" "unprognostic (1.57e-2)" "unprognostic (8.52e-2)" "unprognostic (1.14e-1)" "unprognostic (1.23e-2)" "unprognostic (7.55e-2)" "unprognostic (2.90e-1)" "unprognostic (1.71e-1)" "unprognostic (8.94e-2)" "unprognostic (1.13e-2)" 4.7 3.9 3.9 4.4 8.4 9.8 5.7 8.2 7.9 5.7 3.5 4.9 4.9 2.6 6.7 4.8 4.5 4.2 3.7 3.8 3.4 3.3 4.1 3.1 3.3 6.6 3.2 3.6 6.2 3.3 4.5 4.5 4.4 9.3 3.5 3.8 4.8 4.1 4.8 4.2 5.2 3.5 3.8 3.4 8.9 3.2 15.4 4.2 15.2 3.3 2.9 6.4 3.8 4.3 6.7 3.2 7.6 3.6 2.0 4.1 1.1 7.7 6.7 8.0 7.5 6.4 4.0 6.5 10.2 3.9 8.0 10.4 10.9 6.0 10.3 5.8 2.4 10.5 9.4 4.3 11.0 7.5 5.2 4.7 7.6 6.0 1.1 12.2 6.0 2.2 1.6 8.1 5.1 6.8 8.5 9.0 6.7 7.7 9.0 8.8 3.2 11.5 8.4 12.5 4.7 3.3 5.5 7.3 1.9 9.0 7.4 3.8 8.0 5.7 5.4 11.7 11.0 10.7 7.7 4.6 8.2 10.2 2.3 7.6 7.0 7.6 1.3 4.6 4.0 3.6 2.2 6.7 2.5 1.5 1.0 4.2 4.1 3.5 2.1 2.0 1.7 3.2 1.7 1.1 3.9 8.4 8.2 7.9 3.4 3.3 3.2 3.6 9.3 4.2 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 30.0" "Cell line enhanced" "Detected in some" "ASC diff: 47.0;ASC TERT1: 49.9;BJ hTERT+: 39.4;TIME: 19.7;U-138 MG: 40.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059739 Uncertain "Secreted to blood" 34000000 "HPA059739: " "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavourable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 19.8 0.7 2.6 3.2 1.2 0.0 7.5 0.6 3.7 17.6 4.5 0.4 4.0 0.1 30.0 13.7 4.1 5.1 14.9 5.2 3.1 0.9 2.0 0.9 4.7 0.8 2.6 1.2 4.1 2.3 0.5 1.0 17.0 1.9 4.1 1.5 2.4 5.3 3.9 8.1 2.9 1.4 17.9 2.2 0.9 1.7 9.8 3.4 0.0 3.5 9.0 0.8 12.4 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.0 49.9 0.0 19.2 39.4 4.0 6.1 0.0 0.0 0.0 0.1 7.3 0.0 0.0 1.2 1.9 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.0 16.1 0.3 6.7 1.2 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 2.0 0.0 0.0 19.7 40.1 0.8 9.7 0.0 0.0 0.0 0.0 9.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.2 0.6 3.7 3.1 0.9 2.6 1.2 1.9 3.4 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078333-82098332 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 147.6" "Cell line enhanced" "Detected in many" "SK-BR-3: 152.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" 1600000 "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavourable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavourable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 147.6 7.8 8.2 14.2 11.5 11.1 57.5 19.1 23.0 6.6 27.7 17.0 14.1 8.2 4.7 14.2 17.1 4.3 19.4 6.3 7.9 6.7 3.7 30.8 26.8 9.8 7.3 11.5 6.4 10.4 6.7 15.3 8.4 21.7 28.8 3.4 7.6 16.9 10.8 7.5 17.2 6.5 4.6 8.4 5.1 11.9 6.6 8.8 1.9 5.1 10.7 5.4 8.0 6.6 0.5 1.4 0.0 0.8 0.2 1.9 0.8 23.1 24.3 11.3 7.8 18.3 12.4 24.2 4.6 6.0 4.9 9.0 25.4 15.8 7.7 3.8 3.5 19.4 10.9 21.3 0.9 3.6 47.4 16.0 18.2 33.9 5.2 8.6 2.4 11.9 5.6 12.5 2.9 5.5 24.1 6.9 1.7 40.1 9.4 13.7 21.9 14.2 8.3 6.4 15.3 5.5 29.7 28.1 15.6 6.8 152.8 12.4 27.2 16.5 9.6 7.2 14.8 5.9 11.0 9.3 2.0 8.0 4.3 9.4 10.6 0.0 0.8 0.0 1.2 0.5 0.7 0.5 1.9 1.4 1.4 0.2 0.7 0.6 0.0 0.2 0.4 1.1 0.6 0.8 8.2 11.5 19.1 23.0 7.9 6.7 7.3 11.5 21.7 8.8 FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 248.1;lung: 87.8" "Cell line enhanced" "Detected in some" "HaCaT: 20.1;MCF7: 62.8;RT4: 41.2;SK-BR-3: 12.0;U-698: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "eosinophil: 73.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA005857, HPA012513, CAB033869" Enhanced Uncertain Mitochondria 23000000 Mitochondria "CAB033869: AB_1121520, HPA005857: AB_1848445, HPA012513: AB_1848446" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.40e-1)" "prognostic favourable (5.16e-4)" "unprognostic (1.13e-2)" "unprognostic (1.37e-1)" "prognostic favourable (1.79e-4)" "unprognostic (6.94e-3)" "unprognostic (4.52e-2)" "unprognostic (7.79e-2)" "unprognostic (7.59e-2)" "unprognostic (1.12e-1)" "prognostic favourable (6.86e-7)" "unprognostic (6.91e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "prognostic favourable (1.64e-5)" 19.3 5.8 0.6 2.3 0.9 1.1 7.0 0.4 0.8 2.2 48.8 0.7 17.6 40.7 0.6 2.5 0.7 0.9 9.7 1.3 0.8 0.5 34.6 248.1 87.8 8.9 0.9 0.7 1.0 8.1 17.1 1.9 1.0 1.0 6.4 3.0 1.5 9.1 17.7 0.5 1.7 60.4 3.1 1.2 2.8 10.4 1.0 0.8 0.5 4.3 1.0 1.1 22.4 9.6 0.6 17.1 73.5 30.7 2.8 3.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.1 20.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.3 5.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 62.8 0.0 1.1 0.2 2.2 0.0 0.2 0.4 0.0 41.2 0.2 1.2 0.1 12.0 0.0 7.2 1.7 0.0 0.0 0.2 0.2 0.0 0.0 0.1 29.9 0.0 0.3 0.0 10.6 13.0 73.5 1.5 30.7 2.3 0.6 0.9 0.9 17.1 0.6 3.3 1.6 2.3 2.8 16.3 6.1 0.4 5.2 0.6 0.9 0.4 0.8 0.8 0.5 0.9 0.7 1.0 0.8 FBP2 ENSG00000130957 "Fructose-bisphosphatase 2" O00757 9 94558720-94593793 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 33.7;skeletal muscle: 134.7;tongue: 45.6" "Cell line enhanced" "Detected in some" "BEWO: 7.2;CACO-2: 3.7;HMC-1: 4.0;MCF7: 5.3;PC-3: 3.7;SiHa: 5.0" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 36 "pons and medulla: 33.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA012513, HPA055286, HPA077371" Enhanced Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA012513: AB_1848446, HPA055286: , HPA077371: " "unprognostic (3.88e-2)" "unprognostic (3.54e-4)" "unprognostic (2.38e-1)" "unprognostic (6.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-2)" "unprognostic (9.40e-4)" "unprognostic (3.95e-3)" "unprognostic (5.11e-2)" "unprognostic (2.39e-2)" "unprognostic (4.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.48e-4)" 2.0 0.4 0.1 0.0 0.1 0.0 0.2 0.1 0.9 0.1 0.1 3.8 4.4 1.0 0.1 1.0 1.6 0.1 0.0 0.1 0.7 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.1 1.2 4.1 0.1 0.0 33.7 0.2 0.0 5.0 1.4 1.8 134.7 0.1 0.1 0.1 0.2 0.1 9.0 0.4 0.0 0.0 0.2 45.6 2.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.3 0.0 2.5 0.0 0.0 7.2 0.0 0.0 0.1 0.0 3.7 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 1.9 2.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 2.4 0.6 0.1 5.0 1.2 0.0 0.4 0.1 0.0 0.0 2.3 2.2 0.0 0.0 0.1 1.0 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.7 0.1 0.1 0.0 33.7 0.0 FBXO18 "FBH1, Fbx18, FLJ14590" ENSG00000134452 "F-box protein, helicase, 18" Q8NFZ0 10 5890203-5937594 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002844 Supported "HPA002844: AB_1078829" "unprognostic (3.14e-2)" "unprognostic (1.55e-1)" "unprognostic (6.35e-3)" "unprognostic (4.42e-2)" "unprognostic (3.37e-2)" "unprognostic (8.98e-3)" "prognostic unfavourable (7.73e-7)" "unprognostic (1.89e-1)" "unprognostic (2.42e-1)" "unprognostic (3.37e-2)" "unprognostic (1.56e-2)" "unprognostic (2.23e-1)" "unprognostic (6.91e-3)" "unprognostic (3.69e-1)" "unprognostic (4.35e-2)" "unprognostic (1.24e-1)" "unprognostic (9.54e-2)" 21.3 30.6 21.0 22.4 28.2 18.8 32.7 23.0 21.8 23.5 21.9 18.1 26.3 21.7 30.6 21.2 23.8 28.7 22.8 35.1 21.0 13.4 20.4 23.2 22.5 24.2 19.4 18.0 27.5 26.2 23.3 24.5 23.6 22.5 23.9 22.1 23.1 21.0 24.8 23.6 26.2 23.4 27.5 13.5 29.7 22.4 27.1 20.1 36.8 22.8 14.9 23.3 23.8 33.8 6.1 6.1 4.8 3.2 7.2 9.2 2.5 14.4 15.8 14.9 16.3 34.4 22.8 13.4 16.8 11.6 16.7 18.8 18.7 13.3 13.6 11.1 24.4 21.7 20.1 17.9 15.2 14.7 14.8 13.0 12.5 15.9 23.7 6.4 12.7 28.5 17.4 21.1 9.4 28.2 22.9 14.4 17.6 22.0 15.5 9.5 6.8 9.0 17.2 7.1 22.6 16.3 11.8 8.5 12.8 17.2 15.7 23.3 16.0 13.1 17.6 10.7 12.0 28.2 12.9 14.8 11.6 7.6 14.4 9.5 7.4 0.0 3.2 4.8 3.2 2.5 2.1 4.9 3.3 4.1 3.0 6.1 4.0 2.9 2.1 7.2 1.9 6.1 9.2 2.5 21.0 28.2 23.0 21.8 21.0 13.4 19.4 18.0 22.5 20.1 FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad" P49789 3 59749310-61251459 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 11.9;U-266/70: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "naive CD4 T-cell: 38.3" "Lineage enriched" "Detected in all" 14 "T-cells: 38.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favourable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" 6.4 24.0 13.7 8.0 17.5 9.0 12.1 4.7 13.3 7.9 8.0 21.0 12.4 8.2 6.2 9.5 5.1 9.2 13.0 14.9 15.3 13.8 30.9 10.7 5.2 9.3 19.5 9.3 8.9 11.8 16.3 15.2 4.1 14.4 5.8 7.8 14.0 11.4 9.9 11.6 7.0 7.6 9.1 17.1 6.0 8.1 10.5 18.2 3.7 15.6 5.7 6.9 7.3 6.1 1.6 2.4 1.8 1.8 2.6 38.3 4.7 0.0 0.0 1.0 0.0 0.6 0.0 1.6 0.1 0.1 0.0 0.0 1.8 3.0 2.6 0.5 0.1 0.0 10.0 2.1 0.0 1.4 3.4 2.2 1.3 4.1 2.6 5.6 0.1 6.8 4.1 0.1 5.1 0.0 1.6 8.3 0.1 2.5 10.1 4.5 0.8 0.6 7.5 0.0 11.9 11.2 1.3 2.1 2.8 1.0 6.9 6.5 0.4 0.1 0.0 1.2 0.4 0.1 1.5 24.4 7.4 0.0 2.7 0.0 1.4 1.8 1.8 0.2 0.9 1.2 0.5 1.6 6.9 0.7 2.2 1.4 38.3 6.7 0.3 2.6 0.4 2.4 7.4 4.7 13.7 17.5 4.7 13.3 15.3 13.8 19.5 9.3 14.4 18.2 FOLH1 "FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA" ENSG00000086205 "Folate hydrolase 1" Q04609 11 49146635-49208670 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.7;intestine: 111.2;prostate: 33.8" "Cell line enhanced" "Detected in some" "HAP1: 5.3;RPMI-8226: 3.7;SK-BR-3: 4.4;TIME: 2.8;WM-115: 5.3" "Cancer enriched" "Detected in many" 27 "prostate cancer: 142.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001451, HPA010593" Enhanced "CAB001451: AB_563979, HPA010593: AB_1079685" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "prognostic favourable (5.24e-5)" "unprognostic (2.55e-1)" "unprognostic (8.31e-2)" "prognostic favourable (4.25e-4)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.67e-3)" "unprognostic (2.13e-2)" "unprognostic (2.72e-1)" "prognostic unfavourable (1.30e-6)" "unprognostic (4.81e-2)" "unprognostic (7.27e-2)" "unprognostic (4.74e-3)" "unprognostic (4.04e-1)" 1.2 1.0 10.4 0.9 16.4 0.8 2.5 1.4 12.7 1.4 67.6 37.7 0.0 111.2 1.3 0.8 1.2 2.1 5.0 0.7 16.9 8.7 6.1 15.7 1.1 0.9 19.0 9.1 1.0 0.7 0.7 0.4 0.7 17.7 33.8 0.8 0.6 20.7 0.8 0.6 1.2 61.1 1.0 33.0 1.5 1.0 0.9 16.2 0.0 1.0 0.0 0.8 1.2 0.5 0.9 0.1 0.3 0.8 1.4 1.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.6 0.0 0.2 5.3 0.5 0.0 1.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 1.0 0.0 0.3 0.3 3.7 0.0 0.0 0.4 1.6 0.0 4.4 1.0 1.0 0.0 2.8 0.2 2.7 0.4 0.3 0.1 0.5 0.1 0.0 0.9 5.3 0.1 0.8 0.3 0.9 0.6 0.2 0.6 1.2 0.5 0.0 0.9 0.7 0.3 0.2 1.4 0.5 0.1 0.4 0.0 10.4 16.4 1.4 12.7 16.9 8.7 19.0 9.1 17.7 16.2 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868294 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced "Intracellular and membrane" 65000000 "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favourable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favourable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 15.8 18.0 4.6 24.1 7.1 0.9 8.9 4.2 8.1 13.1 30.2 6.9 28.4 20.4 9.9 35.7 8.7 12.7 22.6 15.0 4.7 6.4 28.9 39.3 20.7 66.7 4.8 4.7 19.4 15.5 12.2 10.9 31.9 8.0 15.2 33.5 13.8 22.6 18.5 6.9 6.6 42.3 7.4 7.1 32.3 14.8 15.6 2.9 11.6 27.3 8.0 25.1 23.6 7.8 8.3 15.2 16.8 34.8 14.4 9.9 19.0 5.2 3.6 0.7 10.9 1.4 0.1 3.8 5.6 11.7 5.9 11.1 4.8 56.3 7.9 14.2 7.1 3.2 5.2 12.0 7.8 5.6 8.7 6.5 3.2 10.8 5.0 0.6 21.8 5.4 6.8 2.1 2.8 2.3 3.0 0.1 7.0 5.7 1.6 5.8 1.8 5.7 8.9 0.0 8.6 22.0 13.6 3.7 3.6 16.2 6.3 8.5 4.7 2.6 0.6 2.0 3.2 13.4 1.9 9.9 10.0 2.8 5.0 19.7 3.2 13.7 34.8 16.8 9.9 34.5 8.5 8.3 7.2 8.4 15.2 4.7 7.0 8.2 4.3 14.4 28.7 8.8 7.0 19.0 4.6 7.1 4.2 8.1 4.7 6.4 4.8 4.7 8.0 2.9 FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494811-143511690 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" 53000000 "HPA031659: AB_10600661, HPA031661: AB_10601681" "unprognostic (1.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "prognostic unfavourable (2.70e-9)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (7.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-3)" "unprognostic (9.18e-2)" "unprognostic (2.69e-1)" "unprognostic (7.25e-2)" "unprognostic (5.07e-2)" 22.6 32.6 10.3 14.2 16.2 11.6 24.1 6.2 11.4 18.5 21.2 17.6 23.1 22.0 17.9 24.8 11.9 17.2 25.0 25.6 11.6 11.8 34.1 45.7 21.7 30.0 20.4 8.7 21.9 32.6 52.3 14.4 40.7 16.9 12.0 28.4 21.4 18.9 24.5 6.7 9.3 29.5 14.6 18.5 20.3 20.4 11.0 16.1 3.6 17.9 8.7 10.3 16.7 15.0 4.1 22.9 9.3 29.3 9.7 6.7 14.9 23.1 13.6 11.9 21.5 17.6 34.7 22.5 21.9 23.6 27.1 46.1 25.9 23.3 0.0 16.4 29.4 0.1 5.9 2.9 37.7 20.8 22.8 7.8 25.4 39.1 25.5 0.0 4.0 18.5 17.4 24.2 10.5 27.5 27.6 12.2 30.5 27.4 0.0 18.1 15.4 18.8 0.0 24.9 17.1 32.2 14.5 9.0 5.9 24.1 16.2 19.7 7.9 19.1 16.1 16.2 13.7 40.3 42.1 4.5 4.9 0.1 18.7 14.3 5.5 9.3 29.3 8.7 4.9 28.8 5.6 4.1 3.6 4.1 22.9 2.5 1.6 3.0 2.0 9.7 20.0 3.5 6.7 14.9 10.3 16.2 6.2 11.4 11.6 11.8 20.4 8.7 16.9 16.1 FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868592-90883458 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "liver: 118.4;placenta: 158.9;salivary gland: 337.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009499 Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" 41000 "Golgi apparatus" Nucleoplasm "CAB009499: AB_2105095" "unprognostic (2.46e-1)" "unprognostic (2.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.30e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-2)" "unprognostic (8.11e-2)" "prognostic unfavourable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (9.92e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (4.52e-3)" "unprognostic (4.57e-2)" "unprognostic (4.46e-2)" "unprognostic (4.27e-3)" "unprognostic (8.20e-2)" 8.3 3.3 3.0 7.5 3.6 16.6 5.9 5.0 4.4 4.1 6.6 2.8 3.5 5.7 4.9 10.8 4.7 4.4 3.9 6.9 3.1 1.8 6.4 118.4 9.5 3.1 2.8 2.7 4.2 22.5 3.8 7.2 158.9 3.5 9.3 2.2 3.0 337.9 4.7 8.7 9.0 5.9 3.1 3.0 8.2 6.0 5.3 2.9 4.8 8.9 5.5 4.1 4.4 4.3 1.5 3.3 10.3 3.3 3.1 1.9 2.0 14.1 8.6 1.9 8.7 14.3 9.2 22.2 17.8 13.6 7.4 5.2 12.6 15.5 0.5 45.9 12.9 25.5 3.9 9.2 1.6 40.7 10.1 24.8 15.5 16.5 7.6 3.4 40.9 10.4 10.4 8.4 3.8 23.6 18.9 2.5 4.9 9.7 1.3 11.2 6.2 2.5 2.2 7.5 3.2 11.5 10.8 3.9 2.6 15.1 8.2 12.6 2.9 9.1 34.7 8.3 17.8 12.7 26.1 4.4 25.1 1.1 15.9 11.2 16.8 7.5 3.3 10.3 1.9 1.1 1.4 1.5 1.2 1.2 2.1 1.0 0.6 0.8 7.4 3.1 0.7 3.3 0.9 2.0 3.0 3.6 5.0 4.4 3.1 1.8 2.8 2.7 3.5 2.9 G3BP1 "G3BP, HDH-VIII" ENSG00000145907 "G3BP stress granule assembly factor 1" Q13283 5 151771045-151812785 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, Transport" "DNA-binding, Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004052, CAB037068" Supported Supported Cytosol 150000 Cytosol "CAB037068: AB_1840864, HPA004052: AB_1849348" "unprognostic (1.31e-1)" "unprognostic (3.94e-2)" "unprognostic (1.19e-3)" "unprognostic (1.28e-2)" "unprognostic (1.05e-1)" "unprognostic (3.09e-2)" "unprognostic (1.03e-3)" "unprognostic (1.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.36e-1)" "unprognostic (2.06e-3)" "unprognostic (1.23e-2)" "prognostic unfavourable (3.33e-4)" "unprognostic (1.97e-1)" "unprognostic (1.33e-1)" "unprognostic (2.11e-2)" "unprognostic (3.88e-2)" 36.7 27.5 21.1 29.1 23.7 12.2 29.7 24.3 21.4 28.5 23.4 27.7 19.6 18.1 29.9 19.3 40.7 26.5 20.7 24.8 21.7 21.2 30.7 44.1 25.9 36.8 31.8 16.7 38.2 30.6 29.9 29.9 27.9 24.9 24.5 27.2 22.6 24.1 19.7 66.4 25.3 22.8 27.0 27.4 28.9 20.6 27.4 25.8 57.1 28.9 37.0 42.3 27.7 34.8 25.6 19.9 19.5 19.1 29.4 40.0 32.1 37.4 29.3 36.1 15.8 46.0 24.9 41.7 37.2 33.8 48.0 57.0 53.8 48.6 69.9 54.7 34.5 35.6 54.5 72.2 63.0 19.3 26.2 43.2 27.1 36.0 26.2 54.1 28.6 24.9 39.4 41.7 41.4 39.5 33.8 34.5 47.0 20.1 45.6 24.0 40.3 30.0 41.8 45.6 33.3 31.5 37.2 34.1 24.7 35.2 51.3 53.8 41.0 30.1 43.1 34.7 40.4 32.8 67.5 21.5 29.6 55.0 26.1 41.6 62.6 19.5 13.9 13.0 25.7 19.1 40.0 25.6 34.4 28.7 18.0 21.9 33.0 32.9 6.1 29.4 16.8 19.9 34.0 32.1 21.1 23.7 24.3 21.4 21.7 21.2 31.8 16.7 24.9 25.8 G6PC "G6PT, GSD1a" ENSG00000131482 "Glucose-6-phosphatase catalytic subunit" P35575 17 42900797-42913369 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 305.4" "Cell line enhanced" "Detected in some" "RH-30: 2.2" "Cancer enriched" "Detected in some" 72 "liver cancer: 151.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052324 Enhanced "HPA052324: " "unprognostic (4.23e-2)" "unprognostic (1.49e-2)" "prognostic favourable (5.42e-5)" "unprognostic (8.37e-2)" "prognostic favourable (3.79e-5)" "unprognostic (4.79e-2)" "unprognostic (6.46e-2)" "unprognostic (2.56e-3)" 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 5.0 0.0 0.0 5.8 0.1 0.0 0.1 0.1 1.9 0.1 0.1 0.1 23.7 305.4 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 33.7 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 2.2 0.5 1.1 0.2 0.5 0.4 0.0 0.4 0.2 0.2 0.5 0.6 0.0 0.7 0.2 0.2 0.0 0.1 0.2 0.3 0.7 0.2 0.2 0.4 0.0 0.0 0.2 0.3 0.1 0.1 0.5 0.8 0.0 1.3 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.7 0.0 0.1 0.5 1.1 0.3 0.3 0.6 2.2 0.2 0.1 0.7 0.4 0.6 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.7 0.2 0.9 0.3 1.4 0.2 1.1 0.2 0.1 0.3 0.1 0.2 1.0 0.2 0.2 0.0 2.2 0.4 0.4 1.1 0.5 0.1 0.5 0.4 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 G6PC2 IGRP ENSG00000152254 "Glucose-6-phosphatase catalytic subunit 2" Q9NQR9 2 168901240-168910000 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "pancreas: 28.8;retina: 12.1" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.1" "Cancer enriched" "Detected in single" 92 "pancreatic cancer: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "unprognostic (6.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.04e-2)" "unprognostic (9.05e-2)" "unprognostic (2.97e-1)" "unprognostic (3.10e-2)" "unprognostic (1.54e-2)" "unprognostic (1.87e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 12.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 G6PC3 UGRP ENSG00000141349 "Glucose-6-phosphatase catalytic subunit 3" Q9BUM1 17 44070735-44076344 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067052 Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA067052: " "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" "unprognostic (3.61e-1)" "prognostic favourable (1.11e-4)" "unprognostic (1.88e-3)" "unprognostic (3.16e-1)" "prognostic unfavourable (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (2.43e-1)" "unprognostic (1.15e-2)" "unprognostic (2.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.87e-3)" "unprognostic (4.53e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.49e-2)" 25.4 38.1 25.8 15.6 25.4 11.1 23.4 12.9 35.3 25.3 17.8 37.8 28.3 21.1 22.0 50.9 14.4 27.7 20.5 22.2 25.4 37.8 42.8 15.3 18.7 29.8 32.9 21.3 28.1 29.1 38.4 37.7 22.2 34.0 26.1 15.2 37.4 27.7 33.8 22.9 9.9 17.7 17.8 33.1 19.7 18.2 20.7 16.0 18.5 35.1 11.4 14.8 21.4 14.0 5.9 33.4 3.1 19.0 7.2 6.1 6.5 10.0 60.3 21.1 34.0 22.5 16.7 14.8 11.6 23.8 27.1 18.2 24.9 16.4 23.2 16.7 25.8 17.4 16.1 24.7 13.0 11.9 24.7 12.7 40.8 45.4 23.4 11.4 16.2 22.0 11.9 25.7 18.1 22.5 13.1 29.7 20.2 28.1 5.6 17.7 26.4 39.3 11.8 13.2 53.8 36.8 23.8 25.4 22.5 12.8 15.3 14.8 42.3 11.7 22.4 26.9 14.3 7.2 16.1 19.7 14.1 6.6 29.9 10.0 34.1 1.2 15.2 3.1 4.6 19.0 5.6 5.5 3.6 4.4 24.6 5.9 4.6 6.1 0.5 7.2 11.1 33.4 3.5 6.5 25.8 25.4 12.9 35.3 25.4 37.8 32.9 21.3 34.0 16.0 GAA ENSG00000171298 "Glucosidase alpha, acid" P10253 17 80101556-80119879 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 23.8;eosinophil: 8.4;intermediate monocyte: 20.0;myeloid DC: 15.6;neutrophil: 10.8;non-classical monocyte: 24.7" "Group enriched" "Detected in all" 9 "dendritic cells: 15.6;granulocytes: 10.8;monocytes: 24.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026970, HPA029126" Enhanced 3000000 "HPA026970: AB_2672065, HPA029126: AB_2672918" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "prognostic unfavourable (7.66e-4)" "unprognostic (2.94e-2)" "unprognostic (1.14e-2)" "unprognostic (7.96e-2)" "unprognostic (2.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.29e-2)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (7.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.78e-2)" "unprognostic (1.18e-1)" 27.5 19.6 13.8 17.0 14.8 11.3 18.6 14.3 23.0 14.9 16.5 23.4 21.7 19.4 20.1 50.9 13.9 18.2 23.5 21.4 13.5 17.6 27.9 44.2 34.0 30.2 18.1 16.1 14.6 29.4 28.8 24.7 84.1 14.9 22.3 7.2 21.9 27.5 22.1 26.3 18.3 15.4 17.2 16.6 35.8 17.4 30.7 14.6 13.9 21.9 14.9 13.5 24.0 13.4 1.4 15.6 10.8 24.7 1.1 1.8 9.8 11.3 22.1 4.4 14.3 13.7 13.8 28.5 7.1 13.1 5.4 4.4 6.5 18.5 4.1 18.9 5.6 4.8 1.3 8.2 1.3 5.2 16.5 0.0 3.7 23.4 23.9 0.5 13.5 29.6 11.8 10.2 3.5 9.6 4.0 17.1 4.0 26.1 1.8 2.6 9.0 15.5 9.8 15.0 6.9 4.4 11.9 5.0 14.5 9.3 10.4 12.7 29.6 16.2 6.1 20.1 10.8 14.5 2.6 40.8 11.3 1.2 6.4 10.5 12.6 0.1 23.8 8.4 1.5 20.0 1.8 1.3 1.2 1.6 15.6 1.4 1.4 0.9 10.8 1.1 24.7 3.8 0.8 9.8 13.8 14.8 14.3 23.0 13.5 17.6 18.1 16.1 14.9 14.6 GALC ENSG00000054983 Galactosylceramidase P54803 14 87837820-87993665 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism, Sphingolipid metabolism" "Glycosidase, Hydrolase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 35.1;HMC-1: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022196 Approved "Intracellular and membrane" 16000 "CAB022196: " "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (9.39e-2)" "unprognostic (3.08e-1)" "unprognostic (9.70e-2)" "unprognostic (1.73e-1)" "unprognostic (6.56e-2)" "unprognostic (8.44e-3)" "unprognostic (8.08e-2)" "unprognostic (1.84e-2)" "unprognostic (6.00e-2)" "unprognostic (2.13e-1)" "unprognostic (6.80e-2)" "unprognostic (2.72e-2)" 13.8 17.7 21.2 13.2 32.2 18.9 15.4 16.3 25.5 12.3 15.8 28.8 9.6 30.3 10.7 12.1 6.5 20.1 17.4 19.6 22.0 19.5 20.5 11.1 23.0 18.0 30.7 20.1 17.3 13.6 14.4 12.6 15.6 24.9 14.1 16.9 13.3 8.9 10.1 9.3 9.4 30.2 9.3 33.8 14.3 14.9 21.6 26.1 8.6 23.5 5.8 7.3 12.6 11.4 1.7 5.7 20.8 10.5 9.4 16.3 6.4 0.0 8.2 3.0 0.0 10.2 9.2 0.0 3.7 7.6 3.6 4.3 4.5 35.1 2.1 11.4 3.6 0.5 0.0 0.4 4.4 1.1 0.2 12.1 0.3 0.0 8.4 0.0 33.2 9.0 2.8 2.4 0.0 9.6 4.0 1.6 6.0 0.8 0.0 1.8 2.7 0.9 0.0 0.2 0.1 5.7 3.3 2.8 6.7 10.3 1.7 0.0 8.5 8.3 8.1 0.0 5.6 2.3 0.0 1.7 3.2 0.0 1.0 2.8 8.0 12.8 9.5 20.8 7.5 10.5 16.3 1.7 5.7 7.2 5.7 0.8 4.2 4.9 7.8 9.4 8.0 1.0 3.2 6.4 21.2 32.2 16.3 25.5 22.0 19.5 30.7 20.1 24.9 26.1 GALNS "GALNAC6S, GAS" ENSG00000141012 "Galactosamine (N-acetyl)-6-sulfatase" P34059 16 88813734-88856970 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Dwarfism, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 7.1;granulocytes: 19.3;monocytes: 11.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026404, HPA042433" Supported Approved Cytosol "Intracellular and membrane" 2400000 Cytosol "CAB026404: , HPA042433: " "unprognostic (3.16e-1)" "unprognostic (9.98e-2)" "unprognostic (4.03e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (8.08e-3)" "prognostic unfavourable (3.66e-4)" "unprognostic (4.15e-3)" "unprognostic (1.32e-1)" "unprognostic (4.84e-3)" "unprognostic (2.00e-1)" "unprognostic (3.53e-2)" "unprognostic (4.12e-3)" "unprognostic (4.24e-2)" "unprognostic (5.54e-2)" "unprognostic (3.59e-2)" "unprognostic (6.84e-2)" 11.9 14.9 9.3 11.2 11.1 25.0 14.8 12.9 15.4 11.1 15.5 11.5 8.8 13.3 9.0 19.9 10.2 14.8 12.7 12.5 11.2 13.9 13.7 17.8 14.7 10.6 11.8 5.2 11.9 7.3 9.9 13.2 15.6 11.6 10.5 8.3 7.1 10.6 9.0 7.1 10.0 17.2 9.4 9.4 10.4 9.5 27.4 8.8 7.9 14.5 6.1 9.0 11.1 13.0 2.1 7.1 19.3 11.2 2.4 3.1 4.7 2.5 19.3 2.8 19.8 22.3 10.7 19.4 8.1 12.6 8.9 6.9 10.1 16.7 3.2 17.2 13.2 14.9 4.1 6.4 5.4 2.1 6.4 2.0 7.9 5.7 15.0 1.5 13.1 14.9 12.5 9.9 2.8 7.6 4.3 1.9 5.2 14.8 4.0 6.4 6.5 9.0 8.6 2.5 5.3 5.5 5.9 7.3 5.6 19.2 1.8 9.6 12.5 14.2 14.1 19.5 14.9 19.9 4.4 2.0 1.9 5.4 21.1 13.1 11.5 0.9 11.2 19.3 3.1 8.0 2.6 2.1 1.8 2.7 7.1 0.9 1.7 2.1 14.2 2.4 5.6 3.0 3.0 4.7 9.3 11.1 12.9 15.4 11.2 13.9 11.8 5.2 11.6 8.8 GANAB "G2AN, GIIA, GluII, KIAA0088" ENSG00000089597 "Glucosidase II alpha subunit" Q14697 11 62624826-62646726 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026874, HPA061426" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" 37000000 "Endoplasmic reticulum" "HPA026874: AB_1849745, HPA061426: AB_2684516" "unprognostic (2.12e-1)" "unprognostic (5.95e-3)" "unprognostic (4.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "prognostic unfavourable (1.27e-5)" "unprognostic (5.80e-3)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.01e-3)" "unprognostic (3.81e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "prognostic unfavourable (9.54e-4)" 33.6 34.6 16.2 23.3 20.7 17.9 30.1 19.9 31.0 38.9 31.5 29.8 43.4 26.0 44.0 38.6 29.2 34.2 33.8 32.6 17.2 16.5 35.9 91.5 31.4 30.2 21.7 19.5 49.0 51.4 56.6 27.3 61.1 20.0 29.4 32.6 33.7 43.5 40.7 28.2 24.5 39.8 37.4 19.5 37.4 31.2 27.7 20.2 41.8 45.6 25.2 34.0 36.0 29.4 14.6 17.5 16.5 18.8 22.5 20.0 17.6 42.3 37.2 46.5 84.3 71.9 62.8 50.4 47.8 71.8 66.2 57.2 31.0 78.9 29.0 96.8 84.4 58.0 56.1 53.7 68.7 23.4 24.2 28.7 51.0 12.9 53.0 44.5 36.1 60.9 34.8 65.8 69.2 61.3 40.6 52.5 59.5 37.2 23.1 14.5 39.4 30.2 30.8 55.7 73.0 32.5 34.7 24.6 33.4 68.3 44.4 50.8 58.1 37.9 46.1 66.3 42.4 52.0 44.4 52.7 60.9 22.2 72.8 23.9 64.5 16.5 15.0 14.4 20.0 18.8 20.0 14.6 13.8 15.9 17.5 13.1 17.9 16.3 7.0 22.5 16.4 11.6 13.0 17.6 16.2 20.7 19.9 31.0 17.2 16.5 21.7 19.5 20.0 20.2 GANC ENSG00000214013 "Glucosidase alpha, neutral C" Q8TET4 15 42273233-42356935 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016949 Approved Approved "Nucleoplasm,Actin filaments" "Nucleoplasm, Actin filaments" "HPA016949: AB_1849465" "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (2.24e-1)" "unprognostic (3.04e-3)" "unprognostic (2.51e-2)" "unprognostic (9.85e-2)" "unprognostic (2.49e-2)" "prognostic favourable (9.76e-4)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (1.46e-1)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "unprognostic (3.14e-1)" "unprognostic (1.55e-2)" "unprognostic (3.74e-2)" 13.3 14.0 12.5 17.3 20.7 17.6 14.4 16.6 14.2 15.8 14.3 25.6 15.4 11.7 17.9 26.0 20.7 12.9 13.0 12.4 13.4 10.4 13.5 18.0 30.5 13.8 25.0 13.7 18.8 13.1 17.4 20.5 10.8 19.8 13.1 17.8 18.3 20.4 13.7 23.9 13.9 15.4 15.9 25.1 15.5 13.1 24.5 22.6 17.4 16.8 12.3 18.3 16.2 16.3 17.6 12.2 9.3 10.1 4.0 7.4 4.7 6.1 3.2 7.9 8.5 9.6 13.5 5.0 13.6 14.7 15.0 12.6 4.7 4.4 3.4 7.4 13.7 12.9 9.4 14.5 10.4 8.4 4.3 8.4 8.5 9.1 8.1 8.1 7.3 9.1 8.7 6.1 10.4 10.1 8.7 9.5 11.8 1.3 5.4 9.0 4.8 4.1 10.5 9.2 11.7 11.3 5.8 5.9 8.4 7.6 6.7 4.8 2.5 19.3 9.2 15.8 4.2 13.0 8.1 10.3 13.6 6.9 7.4 15.0 8.7 9.3 9.3 7.4 3.7 10.1 5.0 16.2 5.7 6.9 12.2 17.6 7.4 4.4 5.0 4.0 8.1 9.6 5.5 4.7 12.5 20.7 16.6 14.2 13.4 10.4 25.0 13.7 19.8 22.6 GARS "CMT2D, DSMAV, GlyRS, SMAD1" ENSG00000106105 "Glycyl-tRNA synthetase" P41250 7 30594681-30634033 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Hydrolase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017896, HPA019097" Enhanced Supported Cytosol "Intracellular and membrane" 660000 Cytosol "HPA017896: AB_1849478, HPA019097: AB_1849480" "prognostic unfavourable (1.02e-4)" "unprognostic (2.46e-2)" "unprognostic (5.45e-2)" "prognostic unfavourable (8.48e-4)" "unprognostic (2.04e-1)" "unprognostic (1.57e-3)" "prognostic unfavourable (8.95e-5)" "unprognostic (7.31e-3)" "unprognostic (4.76e-1)" "unprognostic (4.00e-3)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "prognostic unfavourable (1.70e-5)" "unprognostic (3.92e-1)" "unprognostic (3.40e-2)" "unprognostic (6.32e-2)" "prognostic unfavourable (3.04e-5)" 25.8 27.3 24.5 26.2 28.5 24.6 32.4 31.1 44.7 21.5 23.7 17.0 11.5 17.2 24.1 23.3 43.7 18.6 18.4 25.7 21.1 26.8 27.6 57.2 27.9 28.0 22.9 28.4 35.4 49.4 44.4 33.3 24.3 37.6 17.2 30.2 14.1 28.7 21.6 35.6 33.2 18.1 30.1 17.6 23.5 30.5 29.7 14.9 28.6 31.4 33.9 38.4 22.8 25.7 22.5 26.4 21.2 27.2 15.3 27.6 21.2 33.0 16.4 14.5 51.5 27.2 40.9 27.6 49.5 44.8 25.5 51.7 21.8 16.5 55.7 14.9 60.2 26.2 36.2 31.4 44.9 13.3 16.9 25.7 13.4 18.3 86.4 37.8 22.8 38.9 55.2 36.6 43.5 32.7 50.9 64.9 40.4 20.3 32.9 26.2 39.2 31.4 16.7 12.8 43.2 29.2 14.9 17.6 29.4 13.2 37.0 70.3 33.0 58.0 30.0 12.1 40.7 24.3 31.2 64.2 53.8 65.5 42.3 57.3 56.9 21.2 19.0 17.7 23.2 25.8 23.7 22.5 23.7 25.1 26.4 19.3 25.5 27.6 5.6 15.3 27.2 18.0 25.9 21.2 24.5 28.5 31.1 44.7 21.1 26.8 22.9 28.4 37.6 14.9 GBA "GBA1, GLUC" ENSG00000177628 "Glucosylceramidase beta" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease mutation, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 101.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" 200000 "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" 19.2 29.7 14.8 13.9 24.5 21.9 15.3 8.7 33.4 16.5 20.1 25.2 18.1 13.8 16.9 30.4 18.9 12.7 16.5 13.6 15.8 18.9 31.8 24.6 17.9 15.4 18.5 16.5 13.1 19.2 101.2 32.1 46.2 28.1 14.4 23.5 25.3 22.3 24.3 6.0 21.6 16.6 17.7 19.3 24.5 14.6 9.7 13.1 13.7 22.2 8.7 17.5 16.3 15.2 7.3 13.9 17.9 22.3 6.6 14.0 12.4 8.5 16.5 5.9 8.0 61.7 13.6 6.8 15.1 53.7 22.5 28.5 9.6 31.3 5.9 16.8 35.3 17.3 8.3 10.7 12.0 12.4 5.8 4.9 10.9 5.2 17.7 5.8 20.6 17.8 9.0 47.3 7.2 20.0 5.1 10.0 26.4 18.5 7.1 2.6 3.7 11.7 6.0 9.6 24.2 15.1 6.6 5.6 7.7 13.2 31.7 33.4 23.8 14.1 15.1 17.0 7.6 21.3 12.0 20.0 16.9 4.6 29.7 5.3 13.0 12.2 21.6 9.1 13.4 22.3 8.7 7.3 10.3 9.0 13.9 5.5 7.4 7.8 17.9 6.6 21.2 7.8 14.0 12.4 14.8 24.5 8.7 33.4 15.8 18.9 18.5 16.5 28.1 13.1 GBA2 "AD035, DKFZp762K054, KIAA1605, SPG46" ENSG00000070610 "Glucosylceramidase beta 2" Q9HCG7 9 35736866-35749228 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024026 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Golgi apparatus" Cytosol "HPA024026: AB_1849530" "unprognostic (3.34e-2)" "unprognostic (2.90e-1)" "unprognostic (2.99e-1)" "unprognostic (1.06e-2)" "unprognostic (1.41e-1)" "unprognostic (5.83e-3)" "unprognostic (2.20e-2)" "unprognostic (2.09e-2)" "unprognostic (3.99e-2)" "unprognostic (8.69e-2)" "prognostic favourable (6.00e-4)" "unprognostic (9.01e-3)" "prognostic favourable (1.24e-11)" "unprognostic (7.62e-3)" "unprognostic (2.94e-1)" "unprognostic (7.69e-2)" "prognostic favourable (6.60e-4)" 15.6 19.3 28.9 17.0 23.3 11.0 24.3 42.3 41.6 14.8 35.1 17.0 28.4 41.5 19.0 22.3 16.6 16.8 21.4 34.6 22.4 21.0 34.8 25.0 20.9 17.3 23.7 19.5 16.4 20.9 27.9 27.1 19.3 36.6 23.9 32.8 28.4 27.7 25.5 46.1 23.5 51.1 23.3 21.0 23.4 26.9 11.6 19.5 10.9 25.4 15.5 16.4 18.2 16.9 5.6 6.8 12.2 6.1 3.1 7.3 3.1 8.1 13.5 18.7 18.1 9.1 5.6 19.0 11.1 8.8 11.4 12.0 15.0 6.5 8.8 8.1 6.7 8.6 17.9 7.5 5.7 12.4 12.2 9.4 35.4 16.1 10.1 14.0 23.5 9.6 14.1 9.6 10.1 29.7 9.2 16.9 10.5 8.1 3.8 14.5 19.4 21.5 7.0 7.5 7.4 15.8 19.3 15.3 20.5 6.2 15.7 11.0 10.7 12.7 20.6 12.3 14.9 10.5 13.5 11.5 7.3 7.3 15.5 5.1 9.5 12.2 4.4 2.9 6.0 6.1 4.1 5.0 5.8 7.3 4.2 5.6 3.7 3.2 4.9 3.1 3.7 6.8 4.0 3.1 28.9 23.3 42.3 41.6 22.4 21.0 23.7 19.5 36.6 19.5 GCH1 "DYT14, DYT5, DYT5a, GCH, GTPCH1" ENSG00000131979 "GTP cyclohydrolase 1" P30793 14 54842008-54902852 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" "Allosteric enzyme, Hydrolase" "Disease mutation, Dystonia, Parkinsonism, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.8;liver: 58.2" "Cell line enhanced" "Detected in many" "BEWO: 11.6;Daudi: 13.2;SH-SY5Y: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 11.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "midbrain: 15.7" HPA028612 Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" Nucleoplasm "Nuclear membrane, Cytosol" "HPA028612: AB_10602135" "unprognostic (3.77e-2)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (2.39e-1)" "unprognostic (9.26e-2)" "unprognostic (1.27e-1)" "unprognostic (7.26e-2)" "unprognostic (1.75e-1)" "unprognostic (3.97e-1)" "prognostic favourable (8.69e-4)" "prognostic favourable (1.41e-4)" "unprognostic (1.23e-1)" "unprognostic (1.96e-2)" "unprognostic (7.22e-3)" "unprognostic (1.76e-2)" "unprognostic (2.23e-1)" "prognostic favourable (6.67e-4)" 4.8 5.2 1.3 5.7 4.5 26.8 2.1 0.6 1.1 2.2 5.5 1.2 1.5 7.5 1.8 1.9 3.8 1.3 1.6 1.5 1.6 4.3 7.9 58.2 11.6 6.7 2.9 0.7 1.4 3.2 0.3 2.5 2.5 2.8 2.9 4.0 5.2 2.5 4.7 1.4 2.5 9.1 2.0 1.7 10.0 4.2 3.6 1.1 13.0 2.3 2.0 8.5 2.9 2.5 1.6 3.0 0.4 11.5 2.3 3.2 1.3 1.9 0.6 0.7 3.5 0.0 0.0 11.6 0.0 1.2 0.8 2.2 0.9 0.6 13.2 3.3 0.1 2.0 5.7 0.9 0.0 5.1 4.9 0.3 0.2 1.9 5.6 0.0 1.2 1.4 1.6 1.9 0.0 0.4 0.8 0.0 0.0 6.8 7.1 0.2 1.1 4.5 5.8 1.4 0.0 1.6 2.7 5.8 29.3 2.4 1.5 0.7 5.6 1.6 0.2 0.1 1.9 3.7 2.3 5.6 4.2 3.2 2.4 4.5 0.0 0.0 3.0 0.2 3.0 6.3 2.5 0.8 1.6 2.1 3.0 1.6 3.2 1.8 0.4 2.3 11.5 0.1 2.3 1.3 1.3 4.5 0.6 1.1 1.6 4.3 2.9 0.7 2.8 1.1 GDA ENSG00000119125 "Guanine deaminase" Q9Y2T3 9 72114595-72257193 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.8;intestine: 54.5;liver: 27.6" "Cell line enhanced" "Detected in some" "A-431: 12.7;BJ hTERT+: 9.2;EFO-21: 50.3;HeLa: 17.6;hTCEpi: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 11 "amygdala: 39.7;basal ganglia: 31.5;cerebral cortex: 63.2;hippocampal formation: 79.5;olfactory region: 28.4" "HPA019352, HPA024099, HPA030387" Enhanced Approved Nucleoplasm 1300000 Nucleoplasm "HPA019352: AB_1855593, HPA024099: AB_1855594, HPA030387: AB_10602351" "unprognostic (2.64e-2)" "unprognostic (7.10e-2)" "unprognostic (2.83e-2)" "unprognostic (2.92e-1)" "unprognostic (4.35e-2)" "unprognostic (8.45e-2)" "unprognostic (2.00e-1)" "unprognostic (5.60e-2)" "unprognostic (3.26e-1)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (5.56e-2)" "prognostic favourable (2.66e-5)" "unprognostic (2.23e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (8.30e-4)" 0.5 1.7 26.7 1.8 27.7 0.5 0.5 0.4 33.8 1.0 20.6 0.9 7.7 47.4 2.4 0.6 0.5 4.7 13.1 0.5 25.7 15.0 21.4 27.6 0.5 0.5 2.9 27.4 0.4 1.7 10.8 1.7 10.3 0.8 0.4 5.5 0.0 0.4 4.1 1.1 1.6 54.5 0.5 0.6 0.5 2.0 1.0 0.2 0.0 0.4 1.0 2.6 3.4 0.5 1.4 0.5 3.0 0.7 1.0 1.0 0.1 12.7 1.6 0.0 0.0 0.0 0.0 0.3 0.0 9.2 0.0 0.0 1.1 7.1 0.0 50.3 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.2 0.0 3.4 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 2.9 0.0 0.2 0.9 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 3.0 0.7 0.3 1.0 0.6 0.3 0.6 0.5 0.4 0.3 1.4 0.7 0.7 1.9 1.0 0.4 0.5 0.5 0.1 26.7 27.7 0.4 33.8 25.7 15.0 2.9 27.4 0.8 0.2 GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501689-19522145 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074747 Approved Nucleoplasm,Nucleoli,Vesicles Nucleoli "Nucleoplasm, Vesicles" "HPA074747: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favourable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavourable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favourable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" 20.3 18.5 30.6 11.7 34.3 17.5 23.9 13.5 32.2 18.1 31.0 24.5 23.0 22.7 15.0 22.6 19.0 13.4 17.5 40.7 31.1 17.5 21.1 21.3 22.1 13.1 29.2 20.6 9.9 28.3 35.3 13.9 15.5 20.8 21.4 32.5 12.5 20.4 24.9 42.4 18.5 20.8 27.2 25.3 10.1 22.8 14.8 23.8 9.6 17.9 21.7 12.7 22.8 12.4 4.6 7.4 23.9 12.4 3.7 7.4 4.6 14.6 17.6 9.7 11.5 46.8 17.4 13.9 15.1 26.0 11.8 14.7 10.0 26.2 11.0 19.5 22.0 12.7 13.5 17.8 14.4 11.9 20.8 9.2 17.3 21.6 28.4 12.1 8.6 18.3 28.9 12.6 14.8 15.8 5.1 11.4 12.8 26.4 10.5 11.2 11.3 13.7 15.2 17.8 15.9 29.2 22.5 11.3 10.3 14.7 17.6 13.9 18.0 14.5 16.6 10.0 9.0 13.2 9.2 10.7 10.1 7.6 15.4 18.0 8.9 23.9 11.8 6.4 5.7 10.5 7.3 4.6 6.8 6.6 7.4 3.7 3.6 5.7 19.8 3.7 12.4 4.6 7.4 4.6 30.6 34.3 13.5 32.2 31.1 17.5 29.2 20.6 20.8 23.8 GDPD1 "FLJ37451, GDE4" ENSG00000153982 "Glycerophosphodiester phosphodiesterase domain containing 1" Q8N9F7 17 59220467-59275967 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.3" "Cell line enhanced" "Detected in many" "HEL: 22.2;K-562: 12.6;SCLC-21H: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (8.33e-2)" "unprognostic (6.63e-3)" "unprognostic (2.68e-2)" "unprognostic (5.98e-3)" "unprognostic (7.12e-2)" "unprognostic (5.35e-2)" "unprognostic (4.85e-6)" "prognostic favourable (2.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.36e-2)" "unprognostic (1.24e-3)" "unprognostic (2.73e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-3)" "unprognostic (4.72e-2)" "unprognostic (1.32e-2)" "unprognostic (6.28e-3)" 1.5 3.6 9.4 1.8 13.1 2.3 3.5 16.6 22.3 2.5 3.9 9.2 0.9 10.7 2.8 1.9 1.7 3.2 3.8 2.2 10.6 13.2 4.2 2.0 4.3 1.7 9.3 10.3 2.2 2.3 14.8 3.1 9.2 15.1 4.4 3.1 2.0 4.1 3.0 2.6 2.8 7.8 2.9 7.1 2.8 10.4 13.0 8.9 3.2 5.5 0.3 2.0 3.6 1.7 1.5 2.9 4.5 3.0 3.0 3.5 1.0 0.8 1.3 4.7 3.5 0.6 0.5 3.6 0.5 1.9 0.7 3.5 0.0 1.7 2.1 5.1 0.1 0.7 8.0 0.9 2.0 4.0 8.3 22.2 0.5 3.1 1.8 1.3 4.3 0.7 4.8 2.0 0.5 2.5 12.6 1.3 0.8 0.8 3.8 0.3 1.0 1.2 2.7 0.4 2.0 2.4 1.4 14.1 4.2 1.4 0.4 5.3 3.9 1.3 2.9 0.2 1.6 0.1 0.5 4.3 3.1 0.8 1.2 1.5 2.0 4.5 1.9 0.8 2.2 3.0 1.7 0.7 2.2 3.2 0.9 1.5 3.0 3.5 2.0 3.0 2.3 2.9 1.2 1.0 9.4 13.1 16.6 17.7 10.6 13.2 9.3 10.3 15.1 8.9 GDPD2 "FLJ20207, GDE3, OBDPF" ENSG00000130055 "Glycerophosphodiester phosphodiesterase domain containing 2" Q9HCC8 X 70423031-70433390 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 22.5;intestine: 19.5;lymphoid tissue: 37.5;skin 1: 33.2" "Group enriched" "Detected in some" 7 "AF22: 9.2;NTERA-2: 19.7" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (1.53e-3)" "unprognostic (5.79e-2)" "unprognostic (5.37e-2)" "unprognostic (5.00e-7)" "unprognostic (3.15e-3)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" "unprognostic (8.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.41e-2)" "unprognostic (5.52e-2)" "unprognostic (2.22e-1)" "unprognostic (8.91e-2)" 0.4 0.4 6.8 0.6 5.7 0.4 1.0 1.1 4.0 0.3 13.0 8.2 8.3 8.0 0.4 22.5 0.4 0.5 0.5 0.8 7.6 4.0 0.6 0.3 0.4 0.4 4.3 5.6 0.4 0.4 0.3 2.6 0.4 8.4 0.3 3.0 0.2 1.1 0.6 0.6 33.2 19.5 0.4 1.5 37.5 1.6 0.3 4.9 0.0 0.4 0.6 0.3 1.0 0.3 0.4 0.1 1.4 0.2 0.1 0.2 0.0 0.0 0.0 9.2 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 19.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 0.4 0.1 0.1 1.4 0.1 0.1 0.1 0.0 0.0 6.8 5.7 1.1 4.0 7.6 4.0 4.3 5.6 8.4 4.9 GGH ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63015079-63039171 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 42.5;liver: 59.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 18.2" "Lineage enriched" "Detected in all" 4 "dendritic cells: 18.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved "Intracellular and membrane" 1400000000 "CAB019296: , HPA025226: AB_1849645" "unprognostic (9.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.48e-3)" "prognostic unfavourable (3.99e-7)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavourable (1.65e-4)" "unprognostic (1.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-2)" "unprognostic (9.62e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" 3.5 3.6 7.4 4.7 8.6 12.3 11.8 15.5 9.9 3.5 17.6 1.5 1.0 3.7 2.6 3.7 11.0 1.6 2.8 5.9 7.9 7.6 42.5 59.5 3.5 5.0 4.7 7.0 1.9 4.2 1.0 1.6 17.7 14.8 1.9 26.4 2.2 6.5 1.8 1.7 11.1 3.6 4.2 7.6 3.7 3.2 14.0 3.8 5.2 1.4 14.5 7.6 3.9 6.6 4.1 18.2 2.1 1.9 2.9 1.4 1.4 20.4 19.7 20.2 3.1 19.9 8.4 14.9 12.6 21.6 20.0 29.1 27.5 36.3 14.0 3.6 15.6 17.1 20.0 21.1 29.8 28.4 15.1 23.0 10.6 18.6 3.8 10.7 13.8 6.1 6.0 20.2 9.7 24.2 12.2 51.3 37.5 11.6 5.2 10.7 9.5 18.6 15.6 19.7 18.8 15.5 7.2 8.1 13.8 18.4 20.1 19.1 22.2 11.9 12.8 21.6 24.2 20.7 22.7 24.0 24.4 16.4 33.4 0.0 38.1 0.0 1.9 2.1 1.1 1.1 0.5 4.1 1.3 1.3 0.6 1.9 1.0 1.3 1.8 2.9 1.2 18.2 1.4 1.4 7.4 8.6 15.5 9.9 7.9 7.6 4.7 7.0 14.8 3.8 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24583750-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 54.1;seminal vesicle: 41.7" "Cell line enhanced" "Detected in many" "HDLM-2: 35.8;Karpas-707: 52.7;RPMI-8226: 51.8;RPTEC TERT1: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "HPA045635, HPA047534, HPA065444" Supported Approved Vesicles "Intracellular and membrane" 4600000 Vesicles "HPA045635: , HPA047534: , HPA065444: " "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favourable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favourable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 1.6 0.5 1.7 1.7 2.2 2.7 8.2 2.3 2.6 7.3 7.9 1.6 23.7 22.3 1.4 19.9 1.2 0.8 12.2 2.0 1.8 1.2 54.1 29.2 14.3 3.2 1.7 1.6 1.3 17.3 0.0 1.6 1.4 2.2 14.7 2.4 1.4 8.7 41.7 0.9 1.1 20.9 1.7 1.9 4.7 6.6 5.0 2.1 2.4 4.8 1.6 5.5 2.1 1.1 3.3 7.5 15.9 14.6 6.6 8.6 6.6 0.2 19.4 0.2 0.0 0.0 0.1 0.5 0.1 0.6 0.2 0.2 2.6 4.3 0.2 4.3 0.0 2.8 1.4 0.2 0.1 35.8 2.9 0.1 8.6 14.1 1.5 0.3 12.0 0.4 0.2 0.6 0.4 0.1 2.0 52.7 0.2 0.4 0.3 14.6 1.4 0.2 0.2 2.2 51.8 48.2 0.6 0.2 0.3 0.1 9.4 0.2 9.4 11.1 2.2 3.5 2.3 10.9 0.3 15.8 6.0 0.2 7.4 15.1 0.1 5.2 14.6 0.4 1.4 6.8 5.2 3.3 7.7 3.4 7.5 0.3 1.0 1.9 15.9 6.6 5.5 0.1 8.6 6.6 1.7 2.2 2.3 2.6 1.8 1.2 1.7 1.6 2.2 2.1 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245142 "Enzymes, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "ASC diff: 38.7;ASC TERT1: 29.4;HHSteC: 55.2;HSkMC: 63.6;TIME: 24.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 4.0;eosinophil: 7.5;neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" 18000000 "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavourable (6.36e-5)" "prognostic unfavourable (4.06e-4)" "prognostic unfavourable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 20.2 14.8 2.0 5.2 3.5 0.0 13.2 0.5 4.2 10.7 4.0 5.7 7.9 3.6 2.1 10.2 12.1 14.0 2.4 3.4 13.1 13.7 5.1 12.4 4.7 3.9 5.0 2.2 6.0 3.2 6.5 3.4 5.4 6.8 2.5 5.3 7.2 10.1 2.7 4.8 5.6 1.2 17.2 5.2 6.3 9.3 0.1 0.4 7.5 0.9 0.8 0.1 0.4 0.0 0.3 0.0 0.0 38.7 29.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.1 5.0 55.2 0.6 1.3 63.6 0.0 0.7 0.7 10.3 0.1 0.1 9.9 0.1 0.0 4.8 0.6 0.0 0.0 0.9 0.1 1.1 0.0 0.0 1.3 0.0 1.6 0.0 0.2 0.3 24.7 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.1 0.0 4.0 0.9 7.5 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.9 0.8 0.0 0.1 0.0 0.4 GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.4;salivary gland: 52.7" "Group enriched" "Detected in some" 8 "RT4: 29.8;SK-BR-3: 10.2;T-47d: 31.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved 33000 "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favourable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favourable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" 0.3 0.4 0.3 12.7 0.3 0.0 3.2 0.3 0.4 4.1 24.9 0.4 1.0 17.0 0.9 15.9 25.2 3.0 7.7 0.3 0.3 0.1 18.8 0.6 4.2 0.3 0.3 0.3 1.5 28.6 0.0 1.0 0.4 0.4 5.7 12.7 0.4 52.7 3.7 0.3 25.2 40.4 2.8 0.3 0.3 8.7 0.8 0.3 1.0 0.7 19.6 18.8 16.5 8.2 0.6 0.7 3.5 0.5 0.6 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 29.8 0.1 0.1 0.0 10.2 0.0 31.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.5 0.2 0.4 0.3 0.2 0.3 0.5 0.3 0.1 0.6 0.5 0.4 1.9 0.6 0.5 0.7 0.4 0.0 0.3 0.3 0.3 0.4 0.3 0.1 0.3 0.3 0.4 0.3 GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872860 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles 1500000 Vesicles Nucleoplasm "HPA013204: AB_1850347, HPA013339: " "unprognostic (1.32e-3)" "unprognostic (2.33e-1)" "unprognostic (9.31e-2)" "prognostic unfavourable (1.26e-5)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-3)" "unprognostic (2.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-2)" "unprognostic (3.34e-3)" "unprognostic (3.61e-2)" "unprognostic (5.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-1)" "unprognostic (5.50e-2)" "unprognostic (2.00e-1)" 6.8 6.7 21.6 6.7 23.7 2.9 8.5 42.6 29.1 9.5 11.5 9.7 14.3 9.8 12.3 19.5 6.4 10.5 11.4 13.8 19.7 17.0 9.9 7.2 9.0 10.3 11.2 32.1 13.4 19.5 20.8 18.3 8.5 19.2 11.4 9.6 6.9 18.8 15.3 31.6 11.1 9.0 9.6 11.0 8.3 12.9 5.0 15.6 4.9 16.3 4.3 8.2 9.3 8.5 6.1 2.6 1.5 3.0 3.2 12.8 1.8 2.2 3.3 17.0 17.4 13.4 12.0 15.1 9.4 9.6 7.8 11.6 17.4 11.1 0.0 11.2 7.3 1.5 7.3 4.1 5.1 0.7 13.1 6.7 5.9 9.1 12.0 0.3 11.1 17.4 4.7 8.7 4.0 0.6 5.0 1.2 5.3 3.8 1.7 3.4 3.9 1.7 0.0 11.6 10.7 11.3 3.3 9.9 11.6 4.8 7.7 12.1 5.9 6.1 0.2 26.8 10.7 2.5 5.3 13.1 1.7 0.8 31.5 0.6 9.8 1.5 3.0 1.4 7.4 2.0 2.1 5.6 6.3 2.8 2.6 6.1 12.8 8.9 0.3 3.2 0.7 1.4 4.8 1.8 21.6 23.7 42.6 29.1 19.7 17.0 11.2 32.1 19.2 15.6 GLA GALA ENSG00000102393 "Galactosidase alpha" P06280 X 101397803-101407925 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000237, HPA000966" Enhanced "Intracellular and membrane" 910000 "HPA000237: AB_1078968, HPA000966: AB_1078969" "unprognostic (7.27e-3)" "unprognostic (1.47e-2)" "unprognostic (1.57e-2)" "unprognostic (2.94e-1)" "unprognostic (1.60e-1)" "unprognostic (3.15e-2)" "prognostic unfavourable (5.62e-5)" "unprognostic (2.53e-1)" "unprognostic (3.42e-1)" "unprognostic (1.89e-1)" "unprognostic (2.97e-2)" "unprognostic (3.27e-2)" "unprognostic (2.73e-2)" "prognostic favourable (6.16e-4)" "unprognostic (1.13e-1)" "unprognostic (5.44e-2)" "unprognostic (2.21e-1)" 21.1 22.2 5.2 10.0 6.3 15.6 19.2 6.2 5.7 10.8 12.7 7.3 23.2 14.8 11.7 14.1 9.4 11.5 9.1 10.5 5.2 6.3 28.7 18.9 18.7 12.0 9.4 3.2 9.7 8.3 9.8 10.5 17.9 8.6 8.3 11.2 9.4 9.5 47.7 5.9 8.9 21.3 10.8 11.9 20.8 8.5 4.9 5.8 10.2 8.3 13.4 11.2 12.2 8.9 5.4 15.9 12.8 20.9 3.0 6.1 10.1 7.2 28.4 8.2 8.4 19.0 7.4 3.7 8.3 13.0 15.8 45.2 15.4 11.2 8.0 17.7 8.5 17.3 16.1 9.0 13.7 4.9 11.9 4.4 23.6 18.1 4.9 6.1 81.0 6.5 2.9 18.2 5.3 12.8 6.8 17.7 15.1 12.9 6.1 12.7 12.0 11.5 4.4 10.1 19.5 23.2 14.7 3.0 5.1 19.3 8.2 7.7 3.8 12.6 7.3 5.5 6.6 13.1 6.7 5.4 6.2 6.1 9.5 10.2 6.1 9.5 20.8 6.2 4.6 20.9 6.1 5.4 3.7 5.7 15.9 4.9 3.8 4.7 12.8 3.0 20.8 6.7 4.3 10.1 5.2 6.3 6.2 5.7 5.2 6.3 9.4 3.2 8.6 5.8 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996608-33097230 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" 1700000 Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: , HPA069503: " "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favourable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 17.3 33.1 9.6 14.9 14.7 9.5 18.4 8.9 19.8 18.3 21.9 12.1 19.8 21.2 18.3 55.0 12.7 15.2 25.8 13.7 9.7 10.0 35.0 33.2 24.3 25.0 9.2 9.7 18.3 25.3 28.4 16.4 26.5 14.0 13.6 23.7 23.5 21.1 17.7 6.1 12.9 28.3 15.6 9.8 21.4 22.7 10.0 8.0 8.3 26.9 7.7 19.5 18.4 13.6 11.1 45.2 22.7 39.2 6.8 20.9 20.9 5.6 9.8 6.3 7.6 39.1 20.3 136.7 9.1 24.7 11.7 15.1 13.9 13.6 2.8 8.1 18.6 5.5 6.0 11.6 8.7 16.0 5.0 10.9 5.9 7.1 20.1 7.6 11.2 23.4 11.2 10.6 6.3 18.0 9.8 10.6 12.8 6.6 4.5 5.0 4.3 4.3 3.9 4.2 13.0 12.6 8.4 1.9 6.6 11.7 19.0 11.4 12.6 19.9 10.5 7.5 5.2 10.3 7.7 8.4 13.4 0.9 15.9 11.0 5.7 10.5 39.2 22.7 8.3 34.6 11.8 11.1 10.2 9.1 45.2 10.0 5.4 6.5 15.5 6.8 23.7 9.5 20.9 20.9 9.6 14.7 8.9 19.8 9.7 10.0 9.2 9.7 14.0 8.0 GLS "GLS1, KIAA0838" ENSG00000115419 Glutaminase O94925 2 190880827-190965552 "Enzymes, Predicted intracellular proteins" Hydrolase "Cataract, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 127.9" "Cell line enhanced" "Detected in all" "EFO-21: 138.9;RPTEC TERT1: 63.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036223 Enhanced Supported Mitochondria "Intracellular and membrane" 25000 Mitochondria "HPA036223: AB_10669984" "unprognostic (7.45e-2)" "unprognostic (3.42e-2)" "unprognostic (3.21e-1)" "prognostic unfavourable (3.45e-4)" "unprognostic (1.17e-1)" "unprognostic (2.08e-3)" "unprognostic (2.51e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (8.01e-2)" "unprognostic (9.06e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (5.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.12e-1)" 16.5 37.3 37.8 20.4 24.7 10.7 34.3 43.8 47.3 11.9 13.1 5.8 8.9 36.9 14.6 11.9 7.6 11.0 17.7 15.7 23.3 22.8 127.9 5.3 22.6 25.4 20.6 36.8 14.1 17.0 26.4 10.1 14.8 35.1 9.4 13.1 10.8 9.0 13.9 7.4 13.0 40.9 15.5 11.7 19.3 8.7 6.9 12.1 15.0 17.7 8.0 22.9 14.1 16.1 5.2 5.0 6.0 2.1 3.9 9.4 1.5 6.2 7.0 4.9 6.4 15.4 10.7 12.7 18.8 14.3 13.7 15.8 8.5 6.2 12.9 138.9 39.7 8.2 8.6 7.4 20.1 31.8 5.6 21.4 10.3 10.5 14.1 12.5 10.1 9.7 7.7 10.8 7.4 17.8 9.9 26.4 30.5 3.3 8.4 12.1 13.1 11.5 10.7 12.7 11.2 63.8 11.6 6.8 7.1 25.7 5.7 23.9 2.2 7.7 12.6 19.9 14.6 9.9 22.8 8.5 19.4 17.8 7.1 10.3 15.7 6.0 1.5 2.5 5.5 2.1 9.4 4.8 6.5 7.0 2.2 5.2 6.8 8.1 3.0 3.9 1.4 5.0 5.6 1.5 37.8 24.7 43.8 47.3 23.3 22.8 20.6 36.8 35.1 12.1 GLS2 "GA, GLS, hLGA, LGA" ENSG00000135423 "Glutaminase 2" Q9UI32 12 56470944-56488414 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 92.2" "Cell line enhanced" "Detected in some" "Daudi: 25.1;SCLC-21H: 7.1" "Cancer enhanced" "Detected in single" "liver cancer: 1.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 29 "B-cells: 1.8;T-cells: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038608 Uncertain "HPA038608: AB_10673176" "unprognostic (5.59e-2)" "unprognostic (1.51e-2)" "unprognostic (8.73e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "unprognostic (3.27e-3)" "unprognostic (1.98e-6)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.29e-2)" "unprognostic (1.52e-1)" "unprognostic (5.65e-5)" "unprognostic (1.42e-2)" "unprognostic (2.59e-1)" "unprognostic (9.02e-2)" "unprognostic (4.44e-2)" 0.9 1.7 5.7 1.0 8.6 0.9 1.4 12.8 15.0 1.0 1.2 0.2 0.0 1.0 1.2 2.0 1.4 2.8 0.9 1.0 4.2 4.1 1.6 92.2 1.4 1.2 1.9 9.7 1.2 15.8 3.0 6.2 0.8 8.6 1.4 1.7 2.5 1.4 2.0 0.9 2.0 1.0 1.1 3.2 1.1 1.4 1.1 1.4 0.0 1.4 0.0 1.4 1.1 0.8 1.8 0.0 0.0 0.0 0.0 3.8 1.4 4.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 3.4 0.9 25.1 0.4 0.0 0.6 0.0 3.7 0.0 0.0 3.7 0.0 0.3 4.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.8 0.4 0.0 0.1 4.5 2.6 1.7 7.1 0.4 0.8 0.2 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.3 1.8 3.3 1.0 0.0 0.6 3.8 3.5 0.0 0.0 0.0 0.0 0.6 1.4 5.7 8.6 12.8 15.0 4.2 4.1 1.9 9.7 8.6 1.4 GNE "IBM2, Uae1" ENSG00000159921 "Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase" Q9Y223 9 36214441-36277056 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 55.0;salivary gland: 45.3" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007045, HPA027258" Approved Supported Cytosol Cytosol "HPA007045: AB_1079003, HPA027258: AB_1849873" "unprognostic (7.54e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-3)" "unprognostic (7.28e-2)" "unprognostic (7.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.78e-3)" "unprognostic (5.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.88e-3)" "unprognostic (4.20e-2)" "prognostic favourable (9.28e-11)" "unprognostic (2.90e-1)" "unprognostic (8.28e-2)" "unprognostic (2.95e-1)" "unprognostic (1.72e-2)" 7.7 6.7 6.0 6.5 8.3 8.3 16.6 11.1 12.1 7.9 20.7 7.0 4.6 2.9 8.0 3.9 7.6 6.7 5.2 7.6 7.8 6.8 6.8 55.0 5.5 6.0 6.0 7.8 9.8 8.4 4.1 7.0 20.2 10.2 10.1 30.1 4.8 45.3 5.0 10.5 3.7 7.2 11.7 10.9 4.5 4.9 3.4 5.3 3.2 4.6 4.2 7.9 8.6 7.9 3.9 2.2 1.2 2.7 2.4 4.2 1.8 4.4 19.9 8.9 7.6 10.1 10.1 12.9 6.2 7.9 8.6 11.1 4.8 14.2 5.8 6.6 10.3 1.7 6.7 2.0 9.6 10.9 0.6 5.0 11.7 6.6 6.9 0.1 14.3 6.6 2.0 14.3 13.5 3.6 6.3 12.1 8.3 0.7 8.1 2.6 5.1 11.2 6.7 7.5 1.6 47.6 8.2 7.6 6.9 6.6 2.3 5.7 2.1 5.1 5.2 5.7 5.9 6.8 5.4 5.3 11.3 3.2 7.8 4.3 8.1 0.7 1.7 0.9 2.7 2.2 1.8 2.4 3.4 2.9 1.4 3.9 4.0 4.2 1.2 2.4 2.7 2.2 1.5 1.8 6.0 8.3 11.1 12.1 7.8 6.8 6.0 7.8 10.2 5.3 GNPDA1 "GNPDA, GNPI, GPI, HLN, KIAA0060" ENSG00000113552 "Glucosamine-6-phosphate deaminase 1" P46926 5 141991749-142013041 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" 970000 Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: " "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (6.79e-2)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (8.89e-3)" "prognostic unfavourable (2.60e-6)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.09e-1)" "unprognostic (1.58e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (9.66e-2)" "unprognostic (2.05e-3)" 15.6 28.2 13.9 10.0 19.1 4.3 18.7 12.6 22.5 16.5 13.7 13.2 11.7 18.0 24.8 34.0 10.7 11.9 13.7 10.6 12.3 16.1 46.2 10.2 11.0 21.8 14.1 16.5 20.7 7.7 15.1 19.9 18.9 13.4 17.8 14.0 17.1 10.6 18.9 16.5 9.0 18.8 18.4 10.9 18.2 9.5 16.3 10.8 12.4 18.2 9.2 11.8 23.6 11.2 7.9 20.6 5.0 22.7 5.6 32.7 14.7 11.7 17.2 6.8 33.2 23.1 15.7 15.7 9.3 22.5 24.8 28.3 25.7 14.0 0.0 21.4 6.7 12.5 31.2 27.8 22.0 9.0 13.4 8.6 10.1 18.3 41.1 23.8 11.4 18.7 16.5 15.8 42.2 26.0 10.2 31.8 26.5 7.4 18.1 2.7 25.2 34.8 7.1 21.8 26.2 23.9 32.5 6.0 15.7 18.5 19.3 35.4 15.8 7.5 12.4 14.5 9.9 22.3 13.1 17.9 34.2 13.2 21.3 8.2 12.6 0.0 19.4 2.6 15.7 22.7 32.7 7.9 12.8 14.4 20.6 3.7 15.5 16.5 5.0 5.6 20.4 11.6 10.6 14.7 13.9 19.1 12.6 22.5 12.3 16.1 14.1 16.5 13.4 10.8 GNPDA2 SB52 ENSG00000163281 "Glucosamine-6-phosphate deaminase 2" Q8TDQ7 4 44682200-44726595 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" 710000 Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: " "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (1.90e-2)" "unprognostic (3.29e-1)" "unprognostic (1.55e-3)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "unprognostic (9.57e-2)" "unprognostic (9.75e-3)" "unprognostic (1.03e-1)" "unprognostic (1.28e-3)" "unprognostic (4.18e-2)" "unprognostic (6.86e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" 12.3 13.7 14.8 11.2 21.5 7.3 14.9 47.5 24.5 15.2 12.3 7.3 8.7 8.0 17.5 15.3 11.2 13.3 10.8 17.8 14.5 13.9 14.3 4.3 10.0 11.7 13.7 17.6 24.2 8.1 13.0 29.9 6.6 16.5 15.7 8.5 11.5 9.8 16.2 10.9 10.2 8.7 16.6 12.7 11.4 9.9 11.1 11.3 10.0 18.9 8.4 10.2 13.5 11.0 11.6 3.3 5.8 4.1 8.4 11.4 4.4 9.0 6.3 6.8 5.7 10.6 14.8 2.2 16.1 17.5 10.3 9.7 3.2 11.1 7.8 9.3 13.7 3.1 6.2 15.0 11.7 10.4 7.1 11.2 10.3 5.6 11.8 11.7 10.4 17.4 10.6 10.6 7.9 15.4 6.7 10.4 19.5 0.4 14.0 6.6 3.2 11.7 9.3 14.5 4.4 10.3 5.4 11.7 9.5 7.0 4.1 15.2 8.8 6.9 15.8 14.2 13.3 22.8 18.2 13.5 21.3 11.3 23.2 8.3 12.6 5.8 2.3 4.5 9.7 3.3 11.3 11.6 9.1 9.0 3.3 10.4 11.4 10.9 1.1 8.4 4.1 2.6 9.6 4.4 14.8 21.5 47.5 24.5 14.5 13.9 13.7 17.6 16.5 11.3 GNS ENSG00000135677 "Glucosamine (N-acetyl)-6-sulfatase" P15586 12 64713445-64759447 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 73.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "non-classical monocyte: 50.0" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013695, CAB026011, HPA048508" Enhanced "Intracellular and membrane" 940000 "CAB026011: , HPA013695: AB_1849741, HPA048508: " "unprognostic (8.07e-2)" "unprognostic (2.39e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-2)" "prognostic unfavourable (7.76e-4)" "unprognostic (9.33e-2)" "prognostic unfavourable (1.94e-5)" "unprognostic (1.26e-1)" "unprognostic (4.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.04e-2)" "unprognostic (3.30e-2)" "unprognostic (3.28e-3)" "unprognostic (1.42e-1)" "unprognostic (3.77e-2)" "unprognostic (1.09e-1)" "unprognostic (3.04e-1)" 57.0 96.7 9.0 18.2 10.1 7.4 47.5 7.7 11.6 22.6 19.1 15.4 17.7 11.5 27.1 27.4 14.3 18.7 21.9 33.0 9.0 10.7 48.9 36.7 26.6 48.8 9.6 8.7 32.7 16.0 32.2 16.6 43.5 15.5 18.6 12.8 38.2 17.9 17.1 18.2 13.5 21.6 23.6 10.8 33.6 16.5 19.3 8.4 9.1 31.4 10.4 11.7 23.9 18.2 3.0 18.2 12.9 50.0 3.9 7.0 19.0 8.1 12.6 10.4 17.1 52.4 31.6 22.2 19.0 44.3 22.6 24.9 11.6 11.1 3.5 24.8 24.1 6.7 10.3 10.9 25.6 10.3 7.5 8.3 10.3 7.4 23.8 6.1 73.8 30.2 13.4 23.0 10.5 41.7 5.7 24.8 33.0 6.5 1.5 3.6 4.1 10.7 4.8 16.3 10.8 19.7 24.1 7.1 7.6 24.6 12.0 17.2 21.5 8.2 38.4 22.3 11.8 21.5 11.1 23.5 28.0 3.1 32.1 11.9 15.1 8.8 30.3 5.9 7.0 37.0 5.2 3.0 3.8 5.3 18.2 2.4 4.0 4.0 12.9 3.9 50.0 4.3 2.8 19.0 9.0 10.1 7.7 11.6 9.0 10.7 9.6 8.7 15.5 8.4 GPCPD1 "GDE5, GDPD6, KIAA1434" ENSG00000125772 "Glycerophosphocholine phosphodiesterase 1" Q9NPB8 20 5544404-5611026 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042987 Approved Nucleoplasm Nucleoplasm "HPA042987: " "unprognostic (2.25e-2)" "unprognostic (2.45e-2)" "unprognostic (3.41e-1)" "prognostic favourable (1.30e-4)" "unprognostic (2.93e-2)" "unprognostic (8.10e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-2)" "unprognostic (3.76e-2)" "unprognostic (1.67e-1)" "unprognostic (1.46e-1)" "unprognostic (1.18e-1)" "prognostic unfavourable (3.73e-4)" "unprognostic (1.56e-1)" "unprognostic (1.22e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-2)" 12.9 12.9 10.6 21.8 17.6 56.7 12.7 29.6 28.2 12.2 8.8 9.1 36.7 7.4 12.5 10.5 10.6 12.6 13.2 12.6 12.2 10.1 8.1 8.1 43.6 30.6 13.1 8.9 18.1 8.9 4.5 10.3 13.4 19.4 9.6 10.6 11.0 34.2 31.2 31.8 9.1 15.1 21.5 14.6 24.9 8.8 8.1 4.0 12.1 13.4 17.0 17.5 13.7 9.8 4.2 4.5 16.2 7.1 3.6 4.6 3.4 3.7 7.2 4.9 3.9 3.2 3.8 5.5 5.9 4.8 3.5 2.3 3.7 2.9 8.4 1.1 3.3 1.3 6.1 11.8 3.4 1.8 1.9 11.5 0.8 4.3 15.7 7.1 5.3 8.1 15.4 2.1 25.5 3.6 6.6 4.4 3.1 2.0 6.4 3.8 2.6 4.1 4.6 5.8 3.0 4.7 3.2 1.8 2.4 2.6 11.7 5.6 2.8 19.9 4.1 2.9 2.2 8.0 3.8 4.2 7.2 9.0 0.9 8.7 3.2 2.6 7.1 9.0 4.0 5.5 3.1 4.2 3.0 3.3 4.5 3.8 4.6 3.1 16.2 3.6 5.5 2.0 2.4 3.4 10.6 17.6 29.6 28.2 12.2 10.1 13.1 8.9 19.4 4.0 GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 61.6" "Cell line enhanced" "Detected in many" "Daudi: 10.2;U-698: 10.4" "Cancer enriched" "Detected in some" 11 "liver cancer: 6.8" "Region enriched" "Detected in many" 4 "cerebellum: 8.5" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" 102626666667 3700000000 "CAB008625: AB_1621070, HPA012500: AB_1849931" "unprognostic (6.80e-3)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (4.81e-5)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "prognostic favourable (1.12e-4)" "unprognostic (6.37e-4)" "unprognostic (7.93e-2)" "unprognostic (2.86e-2)" "unprognostic (6.07e-4)" "unprognostic (2.68e-1)" "unprognostic (5.28e-4)" "unprognostic (2.20e-1)" "unprognostic (9.98e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" 2.2 0.4 0.8 0.6 1.2 0.3 0.6 8.5 1.8 0.6 0.6 0.6 0.6 0.1 0.8 0.6 0.6 0.4 0.6 0.6 0.6 1.9 0.6 61.6 0.6 0.6 0.7 0.6 0.7 0.6 1.5 1.3 0.6 0.6 1.0 0.1 0.6 0.6 3.3 0.7 4.8 0.6 0.8 0.6 0.6 0.3 0.8 0.6 6.6 1.6 0.6 0.7 1.0 1.0 1.1 1.6 0.4 0.2 0.1 1.8 0.0 0.7 1.3 1.2 1.8 0.0 0.1 3.0 0.1 0.3 0.4 0.3 5.2 0.1 10.2 1.2 0.2 0.0 1.7 0.3 0.2 1.3 3.4 1.4 1.3 4.3 0.0 1.8 0.2 0.1 0.2 0.1 0.0 0.0 0.6 0.5 0.3 0.7 1.0 0.6 3.9 0.5 2.0 0.3 0.1 0.4 5.1 3.3 3.4 1.1 0.1 0.5 0.5 0.5 0.1 1.2 1.3 0.1 1.4 3.0 4.7 10.4 0.1 0.5 0.5 0.4 0.2 0.1 0.4 0.1 1.4 0.6 0.3 0.2 0.0 1.1 0.3 1.8 0.4 0.1 0.1 1.6 0.2 0.0 0.8 1.2 8.5 1.8 0.6 1.9 0.7 0.6 0.6 0.6 GTF2F2 "BTF4, RAP30, TFIIF" ENSG00000188342 "General transcription factor IIF subunit 2" P13984 13 45120515-45284909 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006912 Supported Supported Nucleoplasm,Microtubules Nucleoplasm Microtubules "HPA006912: AB_1080256" "unprognostic (3.39e-1)" "unprognostic (2.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.29e-1)" "unprognostic (4.51e-2)" "prognostic unfavourable (1.65e-5)" "unprognostic (3.67e-2)" "unprognostic (3.17e-1)" "unprognostic (3.36e-2)" "unprognostic (2.53e-3)" "unprognostic (2.31e-2)" "unprognostic (4.76e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.53e-3)" "unprognostic (3.94e-2)" "unprognostic (6.44e-3)" 15.1 24.7 23.5 21.1 23.6 22.5 20.9 12.0 21.0 16.3 21.8 14.8 18.5 14.9 16.8 23.4 21.8 12.0 15.9 27.5 21.4 21.1 18.3 16.0 15.1 17.5 22.9 19.0 17.3 14.6 16.5 27.5 23.9 18.2 16.7 21.2 18.2 20.8 20.2 32.0 31.5 12.9 28.2 19.5 17.8 15.2 22.2 24.2 22.6 19.2 27.7 19.9 20.5 19.0 15.4 16.3 24.9 15.3 16.1 12.9 8.5 15.4 5.8 11.0 8.1 6.7 9.9 9.1 17.0 11.2 17.3 17.0 9.7 24.2 15.5 9.6 12.4 17.2 16.4 13.6 25.4 11.7 14.2 18.3 7.8 12.6 10.8 20.2 10.5 8.3 21.0 12.9 21.9 11.0 12.9 5.9 46.6 8.6 14.8 23.4 13.0 14.2 14.0 8.3 8.9 37.7 5.4 5.9 9.8 8.6 8.5 14.1 6.9 16.6 8.7 14.6 12.4 11.5 28.9 3.8 5.1 15.5 17.0 13.1 15.2 12.0 14.2 24.9 9.7 14.1 11.5 15.3 11.3 11.5 16.3 15.4 12.9 12.6 19.8 16.1 15.3 12.7 12.3 8.5 23.5 23.6 12.0 21.0 21.4 21.1 22.9 19.0 18.2 24.2 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982314 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" 48000 Vesicles "HPA036322: AB_10670796, HPA036323: " "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 23.5 12.0 3.7 7.9 5.5 20.7 25.4 5.7 4.4 10.4 14.6 7.7 22.0 10.0 10.4 12.2 9.3 7.6 11.1 8.0 3.7 2.9 11.8 50.4 15.3 12.3 6.3 3.1 8.6 17.1 9.0 7.3 30.0 4.5 12.1 11.4 9.9 17.2 11.8 5.9 10.0 16.1 8.3 3.9 17.5 11.0 7.9 5.8 14.7 17.7 5.9 13.0 9.2 7.4 9.7 27.7 22.1 36.0 15.2 11.5 15.8 16.8 6.5 6.4 14.3 21.9 13.1 9.3 5.3 14.9 11.8 10.9 9.3 17.4 7.7 8.4 6.8 6.9 4.1 6.4 7.0 7.2 8.4 10.5 9.8 6.4 10.7 22.4 17.5 9.0 6.9 6.8 8.9 10.2 15.9 55.9 7.6 12.2 8.2 24.1 4.3 5.5 8.5 14.8 43.7 7.4 10.2 9.4 8.3 14.3 33.6 18.7 18.7 22.4 7.2 14.4 13.1 5.4 13.3 31.8 38.1 13.0 10.8 29.9 17.5 7.4 28.1 22.1 11.5 36.0 10.3 9.7 9.0 10.2 27.7 7.8 6.2 7.3 4.5 15.2 30.0 11.3 11.3 15.8 3.7 5.5 5.7 4.4 3.7 2.9 6.3 3.1 4.5 5.8 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102648-55110252 "Enzymes, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 92.3;intestine: 31.0;lymphoid tissue: 40.9" "Cell line enriched" "Detected in some" 4 "HL-60: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 13 "gdT-cell: 92.3;MAIT T-cell: 90.8;memory CD4 T-cell: 25.4;memory CD8 T-cell: 89.3;naive CD8 T-cell: 50.5;NK-cell: 61.9" "Group enriched" "Detected in many" 38 "NK-cells: 61.9;T-cells: 92.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054134 Approved "Secreted to blood" "HPA054134: " "prognostic favourable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favourable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavourable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" 4.3 1.8 1.1 16.3 1.2 10.0 2.5 0.7 0.8 3.9 12.5 0.9 1.3 10.3 5.2 2.9 2.9 2.9 9.6 4.5 1.1 1.1 4.6 5.2 11.8 20.3 1.7 0.9 3.0 5.8 0.0 1.9 5.8 1.5 3.4 6.3 4.5 5.1 1.3 2.6 1.2 31.0 2.5 2.6 40.9 3.9 1.1 0.6 1.9 3.1 4.2 11.1 6.6 2.9 0.2 0.2 2.0 0.3 61.9 92.3 52.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 92.3 0.2 90.8 0.2 25.4 89.3 0.2 0.1 5.2 50.5 2.0 61.9 0.3 0.2 2.9 52.0 1.1 1.2 0.7 0.8 1.1 1.1 1.7 0.9 1.5 0.6 GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "blood: 298.5" "Cell line enriched" "Detected in some" 5 "HMC-1: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in many" 5 "plasmacytoid DC: 298.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 298.5" "CAB000376, HPA003418" Enhanced "Secreted to blood" "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favourable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favourable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavourable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" 6.4 0.7 0.8 8.0 1.1 26.4 3.2 0.7 0.7 1.6 3.0 0.5 1.3 0.8 3.9 1.5 4.0 1.0 3.1 4.8 0.7 2.4 2.1 5.7 21.7 16.7 1.1 0.0 1.4 0.7 0.0 1.0 7.5 0.8 2.6 0.9 4.0 2.7 2.3 3.5 0.6 2.9 1.8 1.5 33.0 3.5 0.9 0.4 6.1 4.4 5.3 16.8 6.0 1.5 0.2 298.5 2.0 0.2 19.9 60.5 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 3.8 0.0 0.0 0.0 0.7 2.9 0.3 0.1 0.2 60.5 0.1 0.7 0.2 4.6 28.4 0.2 0.1 1.4 28.7 2.0 19.9 0.2 298.5 0.1 53.6 0.8 1.1 0.7 0.7 0.7 2.4 1.1 0.0 0.8 0.4 H6PD GDH ENSG00000049239 "Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase" O95479 1 9234775-9271337 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 116.9" "Cell line enhanced" "Detected in many" "ASC diff: 28.6;ASC TERT1: 32.8;HSkMC: 32.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004824, HPA005440" Approved Uncertain Cytosol "Intracellular and membrane" 91000000 Cytosol "HPA004824: AB_1079037, HPA005440: AB_1079036" "unprognostic (4.83e-3)" "unprognostic (3.91e-2)" "unprognostic (1.18e-1)" "unprognostic (3.49e-1)" "unprognostic (5.53e-3)" "unprognostic (2.86e-2)" "unprognostic (8.35e-2)" "unprognostic (5.18e-2)" "unprognostic (9.73e-2)" "unprognostic (1.26e-3)" "unprognostic (2.16e-2)" "unprognostic (7.35e-3)" "unprognostic (8.20e-2)" "unprognostic (3.61e-1)" "unprognostic (1.30e-1)" "unprognostic (8.65e-2)" "unprognostic (1.95e-1)" 18.3 16.1 4.1 10.7 5.5 4.8 12.2 4.1 6.3 16.6 11.9 10.5 8.2 6.3 22.0 18.0 11.1 15.6 11.9 11.9 3.7 3.0 7.0 116.9 12.2 11.1 6.8 2.6 38.3 10.6 8.0 8.7 14.9 6.0 11.6 5.3 11.8 29.8 8.1 24.7 20.7 10.4 10.2 6.6 10.7 9.9 12.4 5.5 16.2 12.6 12.9 14.1 12.2 10.1 4.5 3.7 4.1 6.3 3.1 4.7 3.0 3.8 3.1 2.7 10.2 28.6 32.8 2.6 3.9 9.6 2.9 4.5 0.6 7.9 4.2 4.5 6.0 4.0 0.7 1.9 4.2 12.6 0.9 0.0 1.0 2.6 16.0 1.3 1.6 32.2 3.7 6.9 4.5 13.1 1.1 7.3 5.6 2.2 1.5 3.2 1.5 1.8 0.4 0.3 3.5 3.7 1.6 0.9 4.9 5.1 4.0 4.8 3.0 6.8 13.0 9.9 1.6 2.5 1.0 9.8 2.9 1.0 16.6 6.1 6.2 3.5 6.2 0.9 4.7 6.3 3.7 3.5 3.5 4.1 2.8 4.5 3.4 3.2 4.1 3.1 5.8 3.7 2.8 3.0 4.1 5.5 4.1 6.3 3.7 3.0 6.8 2.6 6.0 5.5 HAGH "GLO2, GLXII, HAGH1" ENSG00000063854 "Hydroxyacylglutathione hydrolase" Q16775 16 1795620-1827194 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 91.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043041, HPA061143" Approved 3000000 "HPA043041: , HPA061143: " "unprognostic (3.11e-1)" "prognostic favourable (5.82e-5)" "unprognostic (2.54e-1)" "unprognostic (1.93e-2)" "unprognostic (5.84e-2)" "unprognostic (1.54e-1)" "prognostic favourable (5.33e-6)" "unprognostic (5.78e-3)" "unprognostic (3.34e-2)" "unprognostic (7.69e-2)" "unprognostic (3.34e-3)" "unprognostic (1.60e-1)" "prognostic favourable (1.81e-6)" "unprognostic (1.20e-1)" "unprognostic (6.24e-2)" "unprognostic (7.18e-3)" "prognostic favourable (5.19e-4)" 14.8 36.9 24.9 7.8 26.7 26.2 16.4 26.8 35.3 9.7 12.9 13.6 19.6 17.6 6.8 13.0 11.7 11.8 9.9 50.9 28.0 24.5 38.8 91.4 14.5 8.5 23.2 24.5 6.3 24.6 17.1 19.7 9.2 18.5 12.4 9.5 11.9 12.5 16.2 67.1 11.0 17.1 11.7 20.7 10.1 13.1 33.8 13.7 7.4 14.1 18.3 7.2 9.7 18.2 13.7 28.9 27.7 36.5 10.9 18.3 12.5 11.4 17.4 15.8 17.8 13.8 5.5 14.2 14.4 13.4 22.3 18.0 8.9 10.0 2.4 29.7 12.3 12.6 14.9 14.4 6.7 23.8 24.0 4.4 17.8 25.5 19.9 5.8 24.2 6.7 31.1 11.1 7.6 19.1 5.8 21.6 7.0 18.9 14.9 12.5 6.0 16.1 12.6 9.9 27.0 28.6 5.2 21.2 18.3 15.8 20.3 31.0 14.9 19.4 14.5 6.8 8.4 14.2 16.5 24.5 23.1 7.1 11.6 5.4 10.8 14.4 15.3 27.7 12.6 25.8 9.2 13.7 16.2 12.9 13.7 12.4 15.8 13.2 13.5 10.9 36.5 28.9 18.3 12.5 24.9 26.7 26.8 35.3 28.0 24.5 23.2 24.5 18.5 13.7 HDAC1 "GON-10, HD1, RPD3L1" ENSG00000116478 "Histone deacetylase 1" Q13547 1 32292086-32333635 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005017, HPA029693, CAB068191" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB005017: AB_2248344, CAB068191: , HPA029693: AB_10601659" "unprognostic (2.51e-2)" "unprognostic (9.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.57e-3)" "prognostic unfavourable (5.76e-7)" "unprognostic (9.57e-2)" "unprognostic (5.02e-2)" "unprognostic (3.47e-2)" "unprognostic (7.06e-2)" "unprognostic (4.44e-2)" "prognostic unfavourable (1.04e-5)" "unprognostic (6.86e-2)" "unprognostic (3.78e-1)" "unprognostic (7.16e-2)" "unprognostic (1.72e-1)" 13.8 22.8 12.8 33.5 14.8 15.0 21.1 5.1 13.0 21.9 35.7 16.0 34.8 22.2 24.6 17.5 40.6 21.0 43.8 12.4 12.5 8.5 21.1 21.5 17.2 33.3 14.7 8.6 27.7 20.5 17.2 27.1 24.4 12.2 25.2 33.9 18.0 27.8 31.3 6.6 16.9 32.7 22.1 13.3 32.6 27.8 20.0 16.7 59.4 36.8 21.2 51.1 26.0 25.1 47.7 32.1 59.8 44.6 42.4 49.2 54.7 29.5 18.0 11.6 23.1 6.8 8.1 24.2 20.9 23.5 28.1 26.0 33.0 53.3 45.6 38.9 23.1 34.6 35.7 28.5 31.2 42.6 35.5 31.4 21.7 25.3 16.1 55.6 45.6 14.7 15.7 21.7 14.4 21.3 41.1 18.2 12.3 22.5 63.3 31.3 26.9 46.2 43.8 27.6 20.3 30.4 42.8 9.1 11.5 35.0 23.6 44.0 27.8 43.3 24.6 18.7 22.0 5.7 51.0 11.1 23.8 62.5 15.4 46.2 24.3 37.0 27.7 59.8 43.2 35.5 35.4 47.7 42.4 46.1 32.1 44.3 49.2 45.7 19.9 42.4 44.6 20.1 42.5 54.7 12.8 14.8 5.1 13.0 12.5 8.5 14.7 8.6 12.2 16.7 HDAC10 DKFZP761B039 ENSG00000100429 "Histone deacetylase 10" Q969S8 22 50245183-50251405 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, DNA damage, DNA recombination, DNA repair" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB045977 Supported "CAB045977: AB_11124034" "unprognostic (1.53e-1)" "prognostic favourable (4.46e-4)" "unprognostic (1.43e-2)" "prognostic favourable (2.45e-5)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (6.15e-3)" "unprognostic (5.48e-2)" "unprognostic (3.28e-1)" "unprognostic (2.56e-2)" "prognostic favourable (9.25e-4)" "unprognostic (4.93e-2)" "prognostic unfavourable (4.74e-11)" "unprognostic (2.21e-2)" "unprognostic (2.52e-2)" "unprognostic (1.43e-2)" "unprognostic (1.38e-3)" 8.9 9.3 10.1 14.7 10.3 16.9 6.8 10.9 8.8 8.6 13.9 4.7 14.6 12.9 7.7 13.5 10.2 7.9 13.1 4.0 8.4 6.1 11.4 15.1 8.2 12.5 4.9 8.8 7.8 15.0 6.4 13.2 7.0 6.1 10.2 3.7 8.8 18.6 12.9 9.2 12.1 14.2 7.1 4.4 17.1 14.2 2.4 4.7 16.1 9.3 7.6 19.2 8.2 7.7 1.1 3.1 5.4 4.2 1.1 1.9 2.5 4.1 2.3 0.6 3.4 3.0 2.3 7.6 2.7 2.4 1.6 0.9 4.3 4.5 2.7 3.9 2.1 6.9 1.4 4.1 0.3 3.4 3.9 5.8 6.1 7.2 5.2 6.8 18.9 4.9 3.0 1.5 0.9 2.9 4.0 4.1 1.4 12.8 3.8 17.0 1.4 5.1 9.1 2.2 16.7 2.5 7.0 1.8 4.5 2.8 1.0 4.8 7.8 11.0 4.7 2.7 3.9 4.6 1.6 5.1 1.7 2.3 4.4 4.3 2.1 0.8 4.0 5.4 1.9 4.2 1.6 1.0 0.9 1.2 3.1 1.1 0.8 1.0 2.0 1.1 2.3 2.7 1.6 2.5 10.1 10.3 10.9 8.8 8.4 6.1 4.9 8.8 6.1 4.7 HDAC11 ENSG00000163517 "Histone deacetylase 11" Q96DB2 3 13479724-13506424 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 27.3;T-47d: 24.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (5.22e-2)" "unprognostic (3.58e-2)" "unprognostic (1.83e-1)" "unprognostic (5.69e-3)" "unprognostic (1.76e-1)" "unprognostic (4.71e-2)" "prognostic unfavourable (1.20e-5)" "unprognostic (4.50e-2)" "unprognostic (5.67e-3)" "unprognostic (1.78e-2)" "unprognostic (9.87e-2)" "unprognostic (3.94e-1)" "prognostic favourable (7.88e-10)" "unprognostic (3.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.46e-1)" "unprognostic (1.39e-3)" 4.8 7.6 24.6 3.2 31.7 0.7 5.8 7.6 30.6 8.8 7.1 29.2 3.8 8.9 6.5 5.1 9.5 10.1 6.5 19.6 24.4 19.0 9.9 2.1 6.4 3.0 25.4 20.7 12.5 18.8 10.4 7.7 3.4 16.5 8.2 5.1 6.6 12.8 9.7 35.1 13.2 9.6 5.4 19.9 3.0 4.9 24.0 20.3 1.5 9.9 4.9 3.7 4.4 6.6 1.4 2.3 7.5 3.3 11.4 4.5 2.3 6.8 4.4 4.7 3.8 6.9 6.1 3.6 4.5 3.1 4.6 3.0 2.2 5.7 0.5 5.4 6.3 5.1 2.7 8.1 2.9 2.9 2.5 1.3 1.9 6.2 7.8 0.1 2.5 5.1 15.2 5.0 3.8 3.2 2.7 1.2 4.3 6.9 0.8 0.9 1.2 11.7 0.9 6.7 1.9 9.4 5.0 0.7 3.5 6.5 27.3 12.9 24.1 1.5 3.0 3.8 7.7 7.5 2.6 0.9 2.4 0.1 1.2 1.0 2.1 0.2 3.3 7.5 4.5 1.8 3.1 1.4 4.1 3.5 2.3 0.6 4.1 2.7 1.4 11.4 0.7 2.3 3.3 2.3 24.6 31.7 7.6 23.0 24.4 19.0 25.4 20.7 16.5 20.3 HDAC2 "RPD3, YAF1" ENSG00000196591 "Histone deacetylase 2" Q92769 6 113933028-114011308 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005054, HPA011727" Supported Enhanced Nucleoplasm Nucleoplasm "CAB005054: AB_562295, HPA011727: AB_1850540" "prognostic unfavourable (7.07e-4)" "unprognostic (1.44e-1)" "unprognostic (2.67e-1)" "unprognostic (2.56e-2)" "unprognostic (2.61e-2)" "unprognostic (1.89e-2)" "prognostic unfavourable (5.39e-10)" "unprognostic (2.03e-1)" "unprognostic (2.63e-2)" "unprognostic (9.00e-2)" "unprognostic (2.01e-1)" "unprognostic (3.92e-1)" "unprognostic (1.84e-2)" "unprognostic (1.96e-1)" "unprognostic (2.42e-1)" "unprognostic (9.80e-2)" "unprognostic (3.51e-1)" 25.8 33.8 25.8 30.1 31.3 34.9 58.7 32.8 36.5 32.1 30.7 25.6 32.2 22.0 38.7 36.7 36.3 32.7 23.3 27.6 26.5 26.9 31.6 22.2 29.9 41.5 29.6 26.5 39.2 31.5 31.7 45.1 38.1 27.9 32.1 36.1 17.5 29.3 39.0 33.9 30.8 26.1 36.1 31.1 30.7 29.9 47.4 27.4 64.0 35.1 31.3 32.5 33.1 47.3 27.0 35.7 28.2 32.6 26.3 32.6 24.3 24.2 16.7 78.2 44.9 20.2 23.0 32.8 28.9 23.7 34.2 41.0 44.3 17.9 20.0 24.2 26.0 19.1 53.0 29.3 57.6 28.5 36.6 48.2 21.7 25.6 26.9 48.9 21.8 18.6 19.7 36.4 34.2 39.8 62.0 20.4 56.5 20.3 43.8 44.3 44.2 23.1 29.8 39.0 18.4 35.3 29.3 52.3 44.4 22.9 21.6 24.1 15.7 57.1 32.1 21.8 25.1 22.8 47.9 16.2 21.3 47.9 18.5 47.2 36.9 23.1 27.6 28.2 21.1 26.6 28.1 27.0 25.9 22.7 35.7 22.3 32.6 29.7 16.3 26.3 32.6 30.9 24.5 24.3 25.8 31.3 32.8 36.5 26.5 26.9 29.6 26.5 27.9 27.4 HDAC3 "HD3, RPD3, RPD3-2" ENSG00000171720 "Histone deacetylase 3" O15379 5 141620876-141636870 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005583, HPA052052, CAB072336" Supported Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "CAB005583: AB_562296, CAB072336: , HPA052052: " "unprognostic (6.65e-2)" "unprognostic (1.96e-1)" "prognostic favourable (3.39e-4)" "unprognostic (1.17e-1)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-2)" "unprognostic (3.16e-1)" "unprognostic (5.56e-2)" "unprognostic (2.45e-2)" "prognostic favourable (3.95e-4)" "unprognostic (1.12e-1)" "prognostic unfavourable (2.65e-6)" "unprognostic (1.85e-1)" "unprognostic (1.63e-2)" "unprognostic (2.28e-3)" "unprognostic (2.17e-1)" 15.9 28.8 19.6 12.2 17.6 18.1 18.6 22.6 20.8 15.6 14.1 11.2 13.1 10.6 17.3 17.6 22.8 16.3 14.0 16.8 18.0 8.9 14.5 23.3 24.4 36.4 13.4 14.2 17.3 24.7 20.9 17.3 14.3 18.8 13.6 14.4 13.6 17.5 13.7 24.5 26.7 15.2 17.2 10.8 20.1 15.5 11.9 12.6 18.5 14.4 9.6 23.7 17.5 17.0 22.1 46.7 16.4 22.6 14.1 23.1 16.9 21.1 14.3 26.6 40.4 25.8 20.6 17.3 15.4 33.9 35.0 50.2 30.7 18.1 30.7 20.0 20.0 18.3 26.8 36.1 43.4 26.2 28.8 24.0 13.2 17.4 18.2 28.9 22.0 17.5 23.3 20.3 26.4 22.5 23.4 16.4 22.1 20.0 32.0 25.0 23.5 11.4 23.2 27.9 22.1 18.7 21.3 22.3 18.1 20.4 21.2 25.4 22.6 18.3 11.3 21.7 13.6 16.6 25.2 13.4 16.4 28.9 18.3 27.5 18.6 13.2 22.4 16.4 15.9 22.6 20.8 22.1 19.8 19.2 46.7 20.1 21.7 18.0 9.5 14.1 19.0 23.9 23.1 16.9 19.6 17.6 22.6 20.8 18.0 8.9 13.4 14.2 18.8 12.6 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 54.6" "Cell line enhanced" "Detected in many" "MOLT-4: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 10.5;classical monocyte: 7.4;neutrophil: 28.3" "Group enriched" "Detected in many" 8 "granulocytes: 28.3;monocytes: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004431, HPA048723" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" "Nuclear speckles" "Nucleoplasm, Cytosol" "CAB004431: AB_627706, HPA048723: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavourable (6.33e-4)" "prognostic favourable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 7.9 6.8 6.1 6.8 5.2 17.1 4.6 6.4 12.3 11.3 21.4 4.6 4.3 2.5 10.2 6.4 8.8 9.0 24.6 5.2 5.0 6.0 3.2 3.1 4.2 4.3 6.1 5.4 8.5 5.8 4.9 8.3 2.5 5.2 7.5 4.8 8.3 3.7 7.3 54.6 6.9 6.5 15.8 4.2 5.4 7.0 8.1 4.3 6.5 4.8 13.2 5.6 10.2 4.6 0.5 1.7 28.3 7.4 2.1 1.2 0.4 4.3 4.3 5.5 6.6 3.1 5.3 6.5 4.5 3.1 3.6 3.4 2.0 7.8 2.0 1.8 3.9 4.3 3.8 1.8 1.8 12.0 2.0 3.2 5.3 6.3 4.2 4.9 2.9 3.6 4.6 6.6 5.3 3.8 4.5 4.6 1.7 5.3 31.6 6.7 4.3 2.2 8.2 10.4 3.2 4.1 5.5 4.4 7.8 6.3 2.8 11.1 1.5 13.4 6.1 4.2 0.3 7.2 6.1 3.3 3.1 3.9 6.1 6.8 8.3 10.5 7.4 1.1 0.9 2.4 1.1 0.5 0.9 0.8 0.8 0.5 0.5 1.0 28.3 2.1 1.0 1.7 1.2 0.4 6.1 5.2 6.4 7.5 5.0 6.0 6.1 5.4 5.2 4.3 HDAC5 "FLJ90614, KIAA0600, NY-CO-9" ENSG00000108840 "Histone deacetylase 5" Q9UQL6 17 44076746-44123702 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019400, HPA030991" Approved Supported "Nuclear speckles,Golgi apparatus,Cytosol" "Nuclear speckles" "Golgi apparatus, Cytosol" "CAB019400: AB_2116626, HPA030991: AB_10795286" "unprognostic (1.30e-2)" "prognostic favourable (6.14e-4)" "unprognostic (6.65e-2)" "unprognostic (8.06e-2)" "unprognostic (3.49e-1)" "unprognostic (3.52e-2)" "prognostic unfavourable (3.12e-5)" "unprognostic (8.80e-3)" "unprognostic (3.80e-2)" "unprognostic (2.37e-2)" "unprognostic (4.91e-3)" "unprognostic (4.30e-1)" "prognostic favourable (3.30e-5)" "unprognostic (1.51e-2)" "unprognostic (3.11e-1)" "unprognostic (6.00e-2)" "unprognostic (1.76e-2)" 15.6 17.6 24.9 7.9 15.8 13.2 18.1 35.9 25.8 16.5 8.8 19.6 9.5 8.4 15.0 11.9 20.1 16.9 11.3 24.4 22.1 24.2 8.6 6.3 13.6 8.8 24.7 22.1 24.5 16.1 28.2 17.5 23.0 19.3 13.6 5.5 11.7 14.2 11.9 42.6 34.0 9.7 12.4 20.5 13.8 9.3 10.3 18.1 7.6 15.0 9.8 8.2 14.9 20.4 7.6 9.4 17.9 13.6 3.5 4.9 5.0 3.5 2.3 6.4 1.5 12.4 9.7 23.1 9.6 24.0 4.8 7.9 5.1 3.8 5.6 3.9 22.8 2.9 7.5 4.1 2.0 8.7 12.2 10.9 7.7 11.7 5.3 3.5 15.4 13.7 7.1 5.5 6.9 3.9 8.1 11.4 27.8 2.7 5.8 10.7 7.0 5.5 22.5 17.9 14.4 0.5 1.6 16.7 8.8 2.8 11.8 13.0 16.8 20.7 2.1 12.1 7.8 2.8 4.8 18.8 15.7 6.7 7.0 4.4 5.7 7.1 7.3 7.7 4.9 11.6 3.5 6.6 3.9 4.9 9.4 7.6 4.1 3.5 17.9 3.5 13.6 8.3 3.5 5.0 24.9 15.8 35.9 25.8 22.1 24.2 24.7 22.1 19.3 18.1 HDAC6 "FLJ16239, HD6, JM21, KIAA0901, PPP1R90" ENSG00000094631 "Histone deacetylase 6" Q9UBN7 X 48801377-48824982 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" "Actin-binding, Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003714, CAB004236, HPA026321" Supported Supported Nucleoplasm 39000 Nucleoplasm "CAB004236: AB_627708, HPA003714: AB_1850544, HPA026321: AB_1850546" "unprognostic (9.53e-2)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (2.42e-2)" "unprognostic (2.82e-2)" "unprognostic (4.11e-3)" "unprognostic (2.17e-2)" "unprognostic (1.16e-1)" "unprognostic (7.68e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-3)" "unprognostic (2.33e-2)" "unprognostic (6.10e-2)" "unprognostic (1.47e-1)" "unprognostic (6.60e-2)" "unprognostic (2.34e-1)" "prognostic favourable (3.34e-4)" 14.6 13.7 23.4 12.8 29.8 19.0 14.4 34.2 30.1 12.7 14.1 24.4 14.9 16.9 16.0 14.7 13.1 15.7 11.7 11.9 21.7 24.8 32.8 43.3 15.1 13.9 27.2 22.4 18.7 15.5 26.7 24.4 15.1 27.0 12.3 15.9 15.1 12.2 15.3 18.2 11.3 16.1 15.0 20.9 15.3 14.2 24.7 22.4 19.0 15.7 9.5 14.0 11.7 12.1 5.7 9.7 6.3 12.4 4.0 5.8 5.0 16.0 13.6 26.7 10.2 10.8 9.8 18.1 7.7 6.5 14.8 14.6 13.1 13.7 15.4 7.4 8.7 11.5 16.2 8.2 12.8 14.4 10.2 21.1 16.2 13.4 10.2 9.7 32.7 14.2 13.3 11.6 14.0 12.3 23.1 17.1 9.3 5.6 13.8 15.3 9.9 13.0 11.9 28.8 15.9 8.5 6.9 13.8 13.6 15.4 4.6 9.2 19.3 9.1 10.0 11.5 14.9 15.8 7.3 15.8 15.6 11.2 11.7 12.5 11.4 0.0 5.8 6.3 5.8 9.7 4.1 4.3 4.0 4.2 8.6 5.7 3.9 3.7 2.9 4.0 12.4 9.7 4.4 5.0 23.4 29.8 34.2 30.1 21.7 24.8 27.2 22.4 27.0 22.4 HDAC7 "DKFZP586J0917, HDAC7A" ENSG00000061273 "Histone deacetylase 7" Q8WUI4 12 47782722-47833132 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 85.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 10.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004775 Supported Cytosol Cytosol "HPA004775: AB_1850548" "unprognostic (3.83e-1)" "unprognostic (9.49e-3)" "unprognostic (1.37e-2)" "unprognostic (4.46e-2)" "unprognostic (6.56e-3)" "unprognostic (2.22e-2)" "unprognostic (2.50e-3)" "unprognostic (1.26e-1)" "prognostic unfavourable (5.16e-4)" "unprognostic (1.28e-1)" "unprognostic (2.07e-1)" "unprognostic (2.38e-2)" "prognostic unfavourable (8.25e-4)" "unprognostic (6.24e-2)" "unprognostic (4.38e-2)" "unprognostic (9.69e-2)" "prognostic favourable (4.65e-4)" 26.0 21.6 8.2 22.7 10.8 17.3 24.4 8.4 10.7 28.2 20.7 8.7 15.4 8.0 27.9 21.5 19.2 25.2 22.1 16.5 10.3 4.3 17.7 5.1 27.6 21.1 8.2 8.0 25.4 8.9 23.7 11.5 17.5 10.0 20.1 4.1 17.6 16.3 18.9 12.5 19.7 13.9 24.9 10.3 23.1 14.9 9.5 11.5 85.8 20.9 12.9 21.0 24.8 25.0 1.4 0.6 10.5 1.9 1.7 1.5 1.8 14.0 9.6 10.0 16.3 7.8 21.9 9.0 13.9 10.8 10.1 6.6 12.8 13.4 28.3 46.2 12.6 13.1 2.3 10.8 3.7 13.2 4.8 9.6 9.4 2.9 8.5 3.0 0.4 14.3 3.8 10.0 5.4 20.8 10.2 11.6 6.4 6.1 27.8 7.5 14.0 10.7 21.4 5.3 10.2 4.3 9.2 2.8 6.8 10.6 4.9 5.0 4.6 4.1 23.5 20.7 22.5 16.8 9.8 26.2 19.0 22.5 8.5 14.3 6.7 0.0 1.9 0.0 1.5 0.8 1.5 1.4 1.3 1.1 0.6 1.1 1.5 1.0 10.5 1.7 0.7 0.5 0.6 1.8 8.2 10.8 8.4 10.7 10.3 4.3 8.2 8.0 10.0 11.5 HDAC8 "HDACL1, MRXS6, RPD3, WTS" ENSG00000147099 "Histone deacetylase 8" Q9BY41 X 72329516-72573103 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Disease mutation, FDA approved drug targets, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048560 Supported Approved "Nucleoplasm,Plasma membrane" "Nucleoplasm, Plasma membrane" "HPA048560: " "unprognostic (1.42e-1)" "unprognostic (6.62e-3)" "unprognostic (3.20e-2)" "unprognostic (9.24e-3)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (4.64e-2)" "unprognostic (6.03e-2)" "unprognostic (1.58e-1)" "unprognostic (2.81e-2)" "unprognostic (3.17e-2)" "unprognostic (9.68e-2)" "unprognostic (8.42e-2)" "unprognostic (2.33e-3)" "unprognostic (9.10e-2)" "unprognostic (7.15e-3)" "unprognostic (2.12e-3)" 9.6 22.5 14.7 9.9 16.2 10.2 12.4 31.4 20.6 12.6 10.4 13.9 11.5 8.6 12.3 28.2 11.0 9.4 9.4 12.6 15.0 15.2 16.8 18.6 10.2 9.6 14.9 9.4 12.8 15.9 13.6 22.0 11.2 19.3 13.3 12.8 14.3 12.2 10.3 10.4 9.3 8.4 13.1 12.2 9.5 10.7 3.6 14.0 8.0 15.0 8.2 11.9 10.4 10.1 9.4 12.8 19.7 13.2 7.7 11.4 7.7 12.3 16.9 12.4 17.2 17.0 12.7 8.6 7.1 13.9 11.0 12.5 12.2 12.7 8.6 22.7 9.8 9.0 23.1 13.9 14.7 14.1 16.4 11.3 21.7 14.2 9.3 18.8 20.1 13.3 10.3 13.5 10.1 16.9 12.6 24.1 14.7 15.5 8.8 24.7 17.2 24.4 12.1 16.0 15.4 19.2 13.0 8.9 19.4 16.9 13.5 17.3 6.8 16.1 12.7 9.1 13.1 13.0 8.0 9.2 14.7 10.9 12.3 20.8 11.7 7.2 13.2 19.7 8.8 11.8 6.9 9.4 9.5 7.3 12.8 9.1 7.6 7.1 0.7 7.7 10.5 4.8 11.4 7.7 14.7 16.2 31.4 20.6 15.0 15.2 14.9 9.4 19.3 14.0 HDAC9 "HD7, HDAC, HDAC7B, KIAA0744, MITR" ENSG00000048052 "Histone deacetylase 9" Q9UKV0 7 18086949-19002416 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 54.3;hTERT-HME1: 26.0;SH-SY5Y: 21.7;U-698: 21.5;WM-115: 22.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 29.5" "Group enriched" "Detected in many" 9 "B-cells: 21.8;dendritic cells: 29.5;monocytes: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028926 Uncertain Approved Nucleoplasm Nucleoplasm "HPA028926: AB_10602327" "unprognostic (2.06e-2)" "unprognostic (2.67e-1)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.74e-1)" "unprognostic (5.54e-2)" "unprognostic (2.20e-2)" "unprognostic (2.32e-1)" "unprognostic (2.21e-1)" "unprognostic (2.45e-1)" "unprognostic (5.01e-1)" "unprognostic (7.58e-2)" "unprognostic (1.29e-1)" "unprognostic (3.94e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" 10.7 13.5 12.6 10.7 16.2 5.9 8.4 19.1 16.9 11.6 7.4 11.3 7.5 3.8 17.8 6.7 4.7 10.5 7.5 14.9 13.1 12.0 3.9 3.1 5.7 18.9 13.9 14.9 3.0 2.7 3.0 17.7 6.8 11.2 12.5 6.2 9.7 6.9 16.5 15.5 3.8 8.4 14.4 17.6 17.4 9.1 8.7 18.2 2.9 5.5 5.4 19.3 7.1 9.6 21.8 29.5 0.5 9.7 2.0 2.1 4.5 12.3 0.0 2.0 0.0 0.3 2.8 0.0 0.7 7.3 3.1 5.3 0.1 4.0 5.3 13.7 8.2 1.8 54.3 1.0 8.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 1.0 1.0 9.6 26.0 0.1 0.0 8.3 4.2 0.0 0.5 1.0 6.6 1.2 1.5 0.8 3.1 1.7 3.3 3.9 21.7 0.1 0.1 3.9 0.2 4.9 0.5 11.3 3.6 0.6 7.0 9.6 4.1 21.5 2.9 0.5 22.2 0.1 9.7 0.0 1.7 6.7 1.7 21.8 0.6 0.8 29.5 16.3 0.0 0.9 0.5 2.0 3.8 6.4 2.1 4.5 12.6 16.2 19.1 16.9 13.1 12.0 13.9 14.9 11.2 18.2 HDDC3 MGC45386 ENSG00000184508 "HD domain containing 3" Q8N4P3 15 90929964-90935196 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040895 Approved Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA040895: AB_10795494" "unprognostic (1.03e-1)" "unprognostic (3.78e-2)" "unprognostic (1.32e-1)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (3.75e-2)" "unprognostic (2.53e-1)" "unprognostic (3.57e-1)" "unprognostic (1.28e-1)" "unprognostic (5.93e-3)" "unprognostic (1.08e-1)" "unprognostic (1.91e-2)" "unprognostic (3.43e-2)" "unprognostic (2.26e-1)" "unprognostic (4.86e-2)" "unprognostic (3.15e-1)" "unprognostic (4.65e-1)" 14.3 18.8 16.3 8.9 17.1 10.7 11.3 10.3 17.6 8.2 13.1 9.3 12.6 12.4 5.4 12.8 7.7 12.7 7.1 15.2 12.9 12.3 14.7 18.3 7.8 9.0 14.6 12.5 10.3 30.3 15.1 10.4 10.4 11.0 8.7 11.1 9.7 24.8 14.0 14.2 9.3 17.1 6.1 11.4 13.1 11.2 4.5 8.2 11.8 12.0 10.1 10.7 7.5 7.5 19.9 25.3 5.6 15.6 16.4 21.5 14.3 6.9 8.5 3.0 3.6 6.9 7.0 5.0 4.6 6.4 4.4 6.5 4.3 14.4 13.0 4.9 3.9 10.8 6.3 10.9 3.7 16.5 13.2 16.5 3.3 9.6 14.1 6.2 8.1 6.1 17.2 8.0 14.4 9.6 13.1 11.8 3.9 10.1 8.5 5.4 2.4 8.8 7.2 1.1 20.8 9.0 7.3 7.6 4.9 3.9 11.0 11.7 16.6 17.0 5.5 2.7 6.1 4.6 6.0 19.4 21.7 9.0 10.1 12.3 8.1 5.6 11.8 4.7 14.0 15.6 18.4 19.9 18.4 16.2 15.9 17.5 21.5 15.7 2.8 16.4 14.2 25.3 17.4 14.3 16.3 17.1 10.3 17.6 12.9 12.3 14.6 12.5 11.0 8.2 HELB ENSG00000127311 "DNA helicase B" Q8NG08 12 66302545-66347645 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (1.33e-1)" "unprognostic (1.67e-1)" "unprognostic (1.97e-1)" "unprognostic (9.06e-3)" "unprognostic (8.65e-2)" "unprognostic (1.34e-2)" "unprognostic (2.00e-1)" "unprognostic (5.22e-2)" "unprognostic (1.20e-1)" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-6)" "unprognostic (3.97e-3)" "unprognostic (9.19e-4)" "unprognostic (1.93e-1)" "unprognostic (9.50e-3)" 3.4 2.1 1.6 12.2 3.9 6.8 2.9 1.3 3.1 2.6 2.7 2.1 1.4 2.3 2.9 2.1 2.7 1.6 2.0 1.8 1.9 1.8 2.7 3.7 4.6 9.9 2.9 0.5 3.0 1.6 2.1 11.9 1.8 4.5 3.1 2.8 0.6 2.9 1.2 1.8 2.8 4.5 1.6 4.7 6.8 3.5 1.8 3.1 11.0 2.8 0.8 8.2 2.6 3.7 1.1 0.9 4.7 0.8 1.6 3.0 0.6 1.3 2.9 1.7 2.0 0.6 1.6 2.3 0.9 0.4 0.9 1.0 2.1 2.1 2.0 2.3 0.7 1.8 1.4 1.2 1.1 4.1 2.2 5.2 2.5 2.1 1.2 3.8 2.6 1.6 0.5 1.4 1.7 1.1 2.0 6.3 1.1 2.1 1.4 6.5 3.2 0.9 1.6 2.4 4.0 1.4 1.1 1.5 1.8 2.3 2.5 1.4 0.9 5.6 1.2 1.2 2.3 1.8 1.7 5.9 2.3 1.1 1.6 3.4 2.2 4.7 0.8 2.2 1.6 0.5 2.2 0.5 2.2 2.0 0.3 1.1 3.0 2.2 2.1 1.6 0.4 0.9 1.9 0.6 1.6 3.9 1.3 3.1 1.9 1.8 2.9 0.5 4.5 3.1 HELQ Hel308 ENSG00000163312 "Helicase, POLQ like" Q8TDG4 4 83407343-83455856 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036852, HPA036853" Approved Approved "Nucleoplasm,Nuclear speckles" "Nuclear speckles" Nucleoplasm "HPA036852: , HPA036853: AB_10672102" "unprognostic (4.58e-2)" "unprognostic (3.25e-2)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" "unprognostic (4.80e-2)" "unprognostic (5.56e-2)" "unprognostic (1.14e-1)" "unprognostic (5.13e-3)" "unprognostic (7.14e-2)" "unprognostic (8.62e-2)" "prognostic favourable (9.07e-4)" "unprognostic (2.03e-1)" "prognostic favourable (2.76e-4)" "unprognostic (3.54e-2)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.37e-1)" 10.5 20.8 6.3 12.2 7.8 7.2 10.4 12.6 9.2 10.7 9.8 9.3 8.2 5.6 9.9 8.7 8.2 9.1 9.0 10.5 6.2 5.7 11.9 10.0 8.0 15.3 6.8 5.7 17.4 8.1 13.3 20.7 11.7 9.0 11.4 7.2 11.0 10.0 10.4 14.6 8.7 9.8 8.0 8.4 14.4 8.4 10.7 7.4 18.5 14.3 8.3 13.4 10.2 9.2 10.1 4.6 6.8 4.7 5.5 9.7 2.9 4.2 3.2 7.0 4.5 8.5 9.0 3.6 6.3 9.5 8.3 8.2 3.1 4.4 11.9 5.1 5.5 4.3 8.4 4.7 8.7 6.9 3.7 7.1 5.3 4.1 5.5 8.6 17.6 7.0 6.3 6.6 6.8 6.6 9.3 10.5 8.4 5.0 7.8 6.2 3.6 2.4 6.1 8.0 4.2 6.8 2.7 5.7 4.7 6.2 6.8 6.9 4.2 9.3 5.0 6.2 5.5 8.0 4.9 9.6 4.1 10.1 5.2 6.5 6.9 5.4 3.7 6.8 5.7 4.0 5.4 5.8 6.3 6.4 4.6 10.1 9.7 8.7 2.3 5.5 4.7 4.5 7.8 2.9 6.3 7.8 12.6 9.2 6.2 5.7 6.8 5.7 9.0 7.4 HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340919-72376476 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA054583 Supported "Intracellular and membrane" 20000000 "HPA054583: AB_2682531" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (3.41e-1)" "prognostic favourable (5.63e-8)" "unprognostic (6.58e-2)" "unprognostic (1.32e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (3.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (9.98e-2)" "unprognostic (3.98e-1)" "unprognostic (7.05e-3)" "unprognostic (3.02e-2)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" 30.1 37.4 23.1 18.0 22.9 35.5 37.8 23.3 28.1 30.6 20.5 19.4 30.1 18.5 25.9 65.7 11.7 21.8 29.2 33.8 23.4 12.8 34.6 29.5 43.9 31.4 24.9 21.1 20.9 22.2 18.1 22.9 37.9 18.8 18.1 26.0 26.9 24.8 22.0 17.7 17.9 24.6 23.4 21.4 31.5 22.6 18.0 22.9 12.1 31.2 11.1 16.4 26.7 17.1 16.1 37.9 22.4 32.7 17.8 18.1 21.3 7.4 12.7 5.5 10.5 45.0 51.4 7.8 10.5 53.3 22.8 36.5 6.7 54.8 6.2 10.1 21.0 15.0 14.4 6.7 14.5 5.0 5.8 7.8 12.6 11.5 34.9 18.7 22.4 43.7 20.0 9.9 17.8 20.8 12.1 38.8 30.3 6.4 4.0 9.4 3.1 0.1 4.2 11.9 14.0 25.5 11.8 4.7 5.2 26.3 24.8 59.3 4.6 23.6 10.4 34.2 14.3 31.4 11.1 20.7 27.9 6.5 12.4 25.0 16.5 8.9 32.7 22.4 18.1 13.7 15.8 16.1 12.0 15.8 37.9 15.6 9.5 14.0 3.1 17.8 4.8 14.4 10.7 21.3 23.1 22.9 23.3 28.1 23.4 12.8 24.9 21.1 18.8 22.9 HEXB ENSG00000049860 "Hexosaminidase subunit beta" P07686 5 74640023-74722647 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 174.3" "Cell line enhanced" "Detected in many" "ASC diff: 112.8;BJ hTERT+: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055409, HPA056010" Enhanced "Intracellular and membrane" 43000000 "HPA055409: AB_2682808, HPA056010: AB_2683008" "unprognostic (3.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.85e-2)" "unprognostic (8.72e-2)" "unprognostic (1.12e-2)" "unprognostic (6.44e-3)" "prognostic unfavourable (3.36e-8)" "unprognostic (2.21e-1)" "unprognostic (5.01e-2)" "unprognostic (1.58e-3)" "unprognostic (6.45e-2)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (1.31e-2)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" 48.0 21.9 7.7 13.6 11.6 11.1 26.1 7.4 11.2 25.8 34.2 9.5 18.0 21.6 22.1 77.3 20.6 17.3 28.1 46.3 7.1 9.1 30.4 44.5 40.9 19.3 8.5 6.7 22.7 30.4 21.8 14.3 174.3 9.3 22.6 26.3 21.0 34.6 13.3 21.0 15.3 33.6 21.0 8.7 20.5 20.7 16.2 6.1 10.8 33.7 15.2 15.4 24.0 19.7 8.9 59.8 23.8 65.9 7.6 16.4 42.9 21.1 16.7 5.8 19.2 112.8 34.8 19.0 26.0 84.4 25.4 55.2 19.5 27.7 0.0 20.7 21.3 17.0 6.2 26.5 33.6 11.8 11.2 2.8 16.2 14.7 33.1 2.3 22.9 30.7 15.6 26.7 17.9 29.1 7.8 34.7 27.8 21.5 2.7 5.3 5.4 7.5 6.4 8.5 27.6 17.5 19.4 3.8 4.7 20.2 13.7 25.1 14.5 15.7 17.2 16.8 4.2 30.8 24.0 16.1 27.6 0.1 38.2 20.8 30.4 14.5 65.9 18.6 14.2 24.5 16.4 8.9 11.7 13.1 59.8 5.5 11.2 10.9 23.8 7.6 14.6 18.0 13.7 42.9 7.7 11.6 7.4 11.2 7.1 9.1 8.5 6.7 9.3 6.1 HEXDC FLJ23825 ENSG00000169660 "Hexosaminidase D" Q8WVB3 17 82418318-82442645 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 72.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 30.3" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022834, HPA023379, HPA027844" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" "Nucleoli fibrillar center, Mitochondria" "HPA022834: AB_1850641, HPA023379: AB_1850643, HPA027844: AB_10600711" "unprognostic (8.69e-3)" "prognostic favourable (7.70e-4)" "unprognostic (7.92e-2)" "unprognostic (1.53e-1)" "unprognostic (3.51e-2)" "prognostic favourable (2.71e-4)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (2.71e-1)" "unprognostic (1.14e-2)" "prognostic favourable (5.57e-4)" "unprognostic (9.04e-3)" "unprognostic (1.83e-1)" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (1.24e-1)" "prognostic favourable (2.52e-5)" 12.7 8.5 7.1 16.6 9.3 14.3 8.7 13.2 7.3 10.1 7.6 8.8 12.8 8.0 10.0 11.1 7.9 10.3 9.4 5.7 7.2 4.6 9.9 11.6 12.4 11.6 12.8 5.5 13.6 72.9 10.2 14.6 5.7 7.4 14.1 4.2 7.0 13.3 9.2 20.4 11.3 12.3 6.0 6.1 15.6 8.8 4.7 11.4 8.6 11.7 8.6 10.7 8.3 8.8 5.9 30.3 3.3 11.5 11.9 9.8 4.4 3.0 7.6 3.4 5.2 10.2 8.9 10.4 3.8 4.7 4.1 4.6 2.6 10.3 7.9 4.2 1.6 4.2 2.0 2.3 1.9 5.5 12.9 3.6 6.7 4.5 9.2 2.4 9.2 6.3 2.3 1.1 4.1 5.2 4.5 2.7 1.1 6.9 8.3 8.9 3.1 4.6 9.8 2.8 15.5 3.1 4.5 4.7 10.1 8.0 5.2 7.2 8.4 9.1 5.2 2.6 5.0 2.0 2.6 12.5 2.3 5.9 2.1 6.8 2.7 3.3 1.7 2.7 9.8 11.5 6.5 4.6 2.2 3.4 2.0 5.9 3.5 5.1 3.0 11.9 4.9 30.3 1.4 4.4 7.1 9.3 13.2 7.3 7.2 4.6 12.8 5.5 7.4 11.4 HFM1 "FLJ36760, FLJ39011, MER3, SEC63D1" ENSG00000162669 "HFM1, ATP dependent DNA helicase homolog" A2PYH4 1 91260766-91404869 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Meiosis "Helicase, Hydrolase" "Disease mutation, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;testis: 19.9" "Cell line enhanced" "Detected in some" "AF22: 9.1;AN3-CA: 4.8;K-562: 4.9;SCLC-21H: 3.1;SH-SY5Y: 3.8;U-266/70: 4.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035036, HPA035557" Supported "Golgi apparatus,Vesicles" "Golgi apparatus, Vesicles" "HPA035036: , HPA035557: AB_10696507" "unprognostic (1.35e-2)" "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.83e-4)" "unprognostic (2.05e-2)" "unprognostic (1.52e-1)" "unprognostic (7.43e-3)" "unprognostic (1.79e-1)" "unprognostic (7.75e-2)" "unprognostic (7.97e-2)" "unprognostic (1.76e-4)" "unprognostic (2.81e-2)" "unprognostic (1.06e-2)" "unprognostic (2.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.77e-4)" "unprognostic (9.59e-2)" 0.8 0.7 2.6 0.3 4.1 0.4 0.8 11.3 4.4 1.7 0.9 1.5 2.7 0.6 3.7 2.5 0.4 1.2 0.6 1.0 2.3 0.9 1.3 0.4 0.5 1.6 0.7 1.4 6.4 1.2 0.1 7.8 0.9 3.9 1.1 0.7 2.7 1.0 2.0 2.3 0.4 0.5 1.7 4.7 0.7 0.6 19.9 1.5 0.0 2.7 0.5 0.4 0.7 2.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 9.1 4.8 0.0 0.2 0.1 0.5 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 1.0 0.0 0.1 0.2 1.1 0.0 0.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.6 0.2 2.4 0.0 0.3 1.4 0.1 0.0 0.0 3.1 3.8 0.0 0.0 1.2 0.0 0.8 0.1 0.0 1.0 0.9 0.1 4.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.6 4.1 11.3 4.4 2.3 0.9 0.7 1.4 3.9 1.5 HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541" Enhanced Approved Nucleoplasm,Mitochondria 90000 "Nucleoplasm, Mitochondria" "HPA036540: AB_10673355, HPA036541: AB_2675182" "unprognostic (3.60e-3)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.36e-3)" "unprognostic (3.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "prognostic favourable (1.22e-4)" "unprognostic (7.32e-2)" "unprognostic (1.37e-2)" "prognostic favourable (1.04e-10)" "unprognostic (1.34e-1)" "unprognostic (3.73e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-3)" 13.7 38.6 18.1 10.1 19.5 5.0 15.8 16.4 18.7 16.3 15.8 14.5 13.0 24.7 17.0 13.0 20.2 10.2 10.0 13.7 18.5 12.7 65.7 56.8 7.6 8.2 20.1 10.8 9.5 29.5 35.8 24.7 7.8 21.0 11.7 18.7 15.0 10.6 12.2 17.5 23.7 16.5 11.3 18.2 9.0 10.4 10.6 22.2 10.5 17.4 15.4 9.3 12.5 49.2 24.2 15.1 14.6 7.6 17.3 20.0 7.3 9.8 7.5 16.2 10.2 15.2 13.5 8.9 10.6 5.7 10.0 10.9 23.3 8.7 14.8 15.1 9.1 18.7 17.1 14.5 15.1 21.3 13.3 19.8 15.8 20.4 5.2 14.1 7.4 10.9 7.9 11.7 2.1 16.2 24.0 13.0 10.9 9.0 14.3 16.2 5.1 15.4 17.9 11.6 37.7 22.6 29.7 12.3 11.6 9.2 13.1 29.9 14.8 11.0 11.5 10.6 9.9 7.1 7.4 8.3 17.7 12.4 9.7 12.3 8.3 12.9 6.7 14.6 11.9 7.6 12.8 24.2 13.3 12.5 11.1 18.7 14.2 18.2 3.5 17.3 5.7 15.1 20.0 7.3 18.1 19.5 16.4 18.7 18.5 12.7 20.1 10.8 21.0 22.2 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066571 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "kidney: 55.4;liver: 146.5;pancreas: 80.1" "Group enriched" "Detected in some" 9 "EFO-21: 19.4;Hep G2: 27.5;T-47d: 13.4" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.2;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 5 "T-cells: 1.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved 1000000 "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favourable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 0.2 0.0 0.3 0.1 0.5 0.0 3.2 0.4 1.1 0.3 0.3 0.2 8.4 0.2 1.1 10.7 0.1 1.9 3.2 0.7 0.6 0.3 55.4 146.5 4.9 0.1 0.9 0.2 0.4 80.1 2.6 3.2 0.2 0.4 5.3 0.0 0.4 4.1 8.5 8.5 0.0 0.2 0.1 0.9 0.3 6.9 0.8 0.3 0.1 4.3 0.4 0.2 0.3 0.1 0.2 0.2 0.0 0.1 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.1 0.0 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.5 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 2.0 0.1 0.1 0.0 0.1 13.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.6 0.2 0.5 1.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.3 0.3 0.5 0.4 1.1 0.6 0.3 0.9 0.2 0.4 0.3 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 24.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 17.8;neutrophil: 12.8" "Group enriched" "Detected in many" 5 "granulocytes: 12.8;monocytes: 17.8" "Region enhanced" "Detected in some" "olfactory region: 4.5" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" 9700000 Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 4.9 5.1 3.0 6.8 3.5 2.2 1.2 0.8 2.4 3.6 6.2 7.1 0.0 2.3 2.9 2.8 14.5 5.7 3.0 5.8 3.2 1.5 3.0 5.6 8.2 16.1 7.1 1.4 7.5 1.1 15.5 2.3 11.3 3.4 1.1 7.0 0.7 12.5 2.1 0.7 6.9 3.6 2.1 7.0 19.0 2.4 6.0 2.8 1.6 1.4 16.9 9.7 2.4 4.9 0.3 1.9 12.8 17.8 1.4 3.4 4.8 8.1 0.4 0.0 1.1 1.9 0.6 0.0 1.0 4.5 2.0 8.7 0.2 6.1 0.2 1.4 2.2 7.9 10.3 1.4 3.6 0.8 0.9 2.2 5.8 0.1 1.1 1.4 4.9 0.8 3.1 1.4 9.8 10.8 0.0 24.7 0.9 1.7 0.1 0.1 0.4 1.5 0.0 0.3 0.3 5.7 0.2 5.8 0.0 11.3 6.2 0.9 0.8 1.9 12.6 0.9 2.8 0.8 1.0 0.3 3.8 0.1 6.5 6.6 1.5 0.2 17.8 0.0 1.0 6.7 0.7 0.2 1.9 0.7 1.9 0.3 1.4 1.2 12.8 1.4 0.9 0.1 3.4 4.8 3.0 3.5 0.8 2.4 3.2 1.5 7.1 1.4 3.4 2.8 HSPA5 "BiP, GRP78" ENSG00000044574 "Heat shock protein family A (Hsp70) member 5" P11021 9 125234853-125241330 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 200.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005221, HPA038845, HPA038846" Enhanced Approved Cytosol "Intracellular and membrane" 1000000000 Cytosol "CAB005221: AB_631616, HPA038845: AB_10673477, HPA038846: AB_10673478" "unprognostic (3.98e-2)" "unprognostic (2.50e-3)" "unprognostic (6.64e-2)" "unprognostic (9.60e-3)" "unprognostic (1.54e-3)" "unprognostic (6.02e-3)" "unprognostic (9.08e-3)" "unprognostic (9.11e-3)" "unprognostic (4.50e-2)" "unprognostic (7.45e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "prognostic unfavourable (3.05e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (7.28e-2)" "unprognostic (3.66e-2)" 44.2 40.3 26.3 40.8 38.4 125.0 58.8 19.5 26.9 37.7 29.3 19.8 47.0 25.5 31.6 75.3 34.1 31.1 25.5 72.7 23.3 28.6 60.4 147.6 43.6 32.7 34.3 14.3 36.2 110.3 41.1 47.6 62.6 43.5 34.3 33.0 16.5 84.9 40.7 23.9 32.3 38.3 33.8 28.2 33.8 35.1 33.0 41.5 23.2 219.3 21.7 29.8 50.4 75.1 33.3 53.8 57.4 55.3 51.9 63.0 90.0 35.5 24.1 31.7 41.9 38.0 43.9 74.7 64.1 50.9 47.7 56.0 37.2 71.2 41.1 40.1 46.8 45.5 28.3 57.3 51.3 23.8 14.3 24.6 30.1 67.2 200.7 33.5 46.6 27.0 112.5 38.3 167.9 74.1 18.2 57.5 34.7 26.3 14.8 23.7 35.8 24.2 14.0 32.3 66.7 46.2 23.6 16.4 29.2 40.8 43.7 65.4 45.0 24.5 49.7 29.1 28.4 29.7 29.8 60.2 57.5 34.8 70.7 28.3 43.8 57.4 55.3 44.3 61.9 54.8 63.0 33.3 45.7 57.7 48.6 24.9 37.6 46.6 44.3 51.9 35.5 53.8 31.2 90.0 26.3 38.4 19.5 26.9 23.3 28.6 34.3 14.3 43.5 41.5 HSPD1 "GroEL, HSP60, SPG13" ENSG00000144381 "Heat shock protein family D (Hsp60) member 1" P10809 2 197486581-197516737 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, Isomerase" "Cancer-related genes, Disease mutation, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 162.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA001523, CAB002775, HPA050025, CAB072816" Supported Enhanced Mitochondria 53000000 Mitochondria "CAB002775: , CAB072816: , HPA001523: AB_1079028, HPA050025: AB_2680995" "unprognostic (2.79e-2)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "prognostic unfavourable (1.61e-4)" "unprognostic (2.59e-1)" "unprognostic (3.57e-3)" "prognostic unfavourable (2.25e-4)" "unprognostic (3.51e-2)" "unprognostic (9.91e-2)" "unprognostic (8.63e-3)" "unprognostic (3.47e-2)" "unprognostic (7.83e-3)" "unprognostic (5.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (4.10e-2)" 28.5 125.2 28.7 23.4 31.8 21.0 55.9 18.2 24.3 17.4 30.3 17.8 23.3 28.9 17.5 18.5 27.2 25.3 16.3 24.0 24.2 27.8 67.1 147.5 22.4 25.3 35.5 16.1 30.2 50.6 32.5 25.9 27.1 33.6 25.9 37.2 11.9 17.6 21.0 36.4 13.7 32.0 23.6 32.4 22.7 25.2 10.9 35.8 22.7 38.7 29.4 30.3 33.3 162.6 25.6 30.3 6.2 29.3 23.1 33.5 22.2 40.4 49.8 41.8 37.5 28.7 30.0 60.8 42.2 22.3 50.8 37.3 167.0 24.4 123.1 55.1 22.0 41.4 163.6 46.5 72.1 30.2 65.6 87.4 80.6 193.3 27.0 96.8 27.5 33.9 54.0 45.0 79.4 39.8 107.6 48.3 37.3 51.8 60.1 98.0 82.6 104.2 72.3 51.6 88.9 53.4 42.3 54.8 31.0 42.3 45.8 54.1 31.7 57.5 17.7 31.6 43.8 40.6 66.6 27.1 59.6 102.2 37.1 58.5 33.9 4.5 19.7 5.3 15.5 29.3 28.8 25.6 25.0 21.8 30.3 21.0 33.5 29.0 6.2 23.1 25.8 20.2 19.7 22.2 28.7 31.8 18.2 24.3 24.2 27.8 35.5 16.1 33.6 35.8 HTRA2 "OMI, PARK13, PRSS25" ENSG00000115317 "HtrA serine peptidase 2" O43464 2 74529377-74533348 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Apoptosis "Hydrolase, Protease, Serine protease" "Disease mutation, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004004, HPA006602, HPA027366" Uncertain Supported Mitochondria Mitochondria "CAB004004: AB_326421, HPA006602: , HPA027366: AB_1851301" "unprognostic (3.09e-1)" "unprognostic (4.06e-2)" "unprognostic (2.82e-1)" "unprognostic (2.58e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavourable (7.77e-8)" "unprognostic (2.12e-3)" "unprognostic (4.18e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-2)" "unprognostic (8.15e-2)" "unprognostic (7.23e-3)" "unprognostic (4.03e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-2)" 16.4 12.7 10.6 14.9 11.3 18.9 12.9 10.7 17.7 12.3 12.8 12.6 9.7 12.6 12.9 6.9 10.7 10.6 9.0 12.9 11.6 8.7 13.1 11.4 11.3 13.2 10.8 11.9 18.7 12.9 10.5 9.0 10.4 13.5 11.6 5.5 10.2 13.1 9.2 17.6 9.0 12.6 11.8 9.1 17.3 11.8 13.9 12.6 12.2 16.8 12.6 9.3 10.4 15.2 12.9 9.4 5.9 8.1 5.5 7.8 7.0 7.9 4.9 5.7 4.9 7.9 3.2 15.2 6.9 3.6 4.2 2.4 9.1 3.5 7.2 5.4 3.9 9.0 6.7 7.9 1.1 16.2 13.4 14.4 4.7 8.0 7.4 6.7 10.6 3.8 5.3 7.9 6.7 5.2 18.9 10.7 3.1 5.2 12.4 14.2 4.7 14.2 8.5 16.1 7.9 3.4 3.2 6.6 7.9 3.7 8.5 13.2 3.9 6.6 3.7 7.3 9.0 14.7 15.4 13.1 4.3 4.7 6.3 10.7 5.8 5.9 8.1 4.8 7.3 6.2 7.8 12.9 7.3 6.2 9.4 11.6 6.3 6.4 3.2 5.5 4.7 6.6 7.4 7.0 10.6 11.3 10.7 17.7 11.6 8.7 10.8 11.9 13.5 12.6 HYAL1 "FUS2, HYAL-1, LUCA1, NAT6" ENSG00000114378 "Hyaluronoglucosaminidase 1" Q12794 3 50299889-50312381 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 105.8" "Group enriched" "Detected in some" 4 "Hep G2: 44.8;SK-BR-3: 13.0" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 7.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" 15000 "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favourable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favourable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" 4.9 6.3 1.0 0.9 1.3 0.0 8.4 0.9 1.4 2.9 1.8 1.7 1.3 1.2 3.5 3.5 5.8 1.9 19.3 18.2 1.1 0.5 25.0 105.8 11.3 2.5 1.2 0.9 1.9 3.1 8.0 0.8 1.3 2.9 1.4 1.0 3.1 3.6 1.2 5.2 5.8 1.4 2.7 1.2 28.0 7.2 1.7 0.8 0.2 3.1 4.2 1.0 1.3 4.3 1.2 1.1 7.3 0.9 0.7 1.5 0.2 1.3 0.8 0.1 0.4 0.2 0.3 0.2 0.0 0.1 0.0 0.2 5.1 1.3 0.0 0.3 0.2 3.1 0.1 0.2 0.0 0.0 0.0 0.1 3.8 44.8 2.1 0.3 0.3 1.8 6.5 0.0 0.2 1.3 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.1 0.1 2.7 0.1 0.0 1.0 0.0 13.0 0.1 0.9 0.1 0.8 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.1 2.2 0.9 2.9 0.7 0.3 1.5 0.9 0.7 1.0 0.4 1.2 1.5 0.8 7.3 0.7 0.7 1.1 0.9 0.2 1.0 1.3 0.9 1.4 1.1 0.5 1.2 0.9 2.9 0.8 HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronoglucosaminidase 2" Q12891 3 50317790-50322906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 107.0" "Group enriched" "Detected in all" 4 "HUVEC TERT2: 67.2;TIME: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain "HPA036436: AB_10670104" "unprognostic (9.97e-3)" "unprognostic (2.60e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-3)" "unprognostic (3.44e-1)" "unprognostic (7.41e-2)" "unprognostic (7.93e-2)" "unprognostic (4.70e-1)" "unprognostic (1.44e-1)" "unprognostic (6.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (7.02e-3)" "unprognostic (5.62e-2)" 46.5 16.4 5.4 11.0 13.9 1.2 52.1 3.5 7.6 16.0 9.5 6.6 9.0 7.3 18.8 11.3 16.0 16.5 19.9 33.6 11.1 6.0 35.7 20.2 61.1 25.6 7.5 4.0 13.6 11.2 7.9 11.9 34.4 16.3 10.3 4.8 20.4 10.9 9.7 11.6 9.7 9.9 15.1 8.0 107.0 10.2 8.6 5.5 1.1 23.2 16.0 8.3 14.8 20.2 0.9 4.4 8.6 11.3 2.0 3.4 2.6 4.8 7.1 11.7 12.0 7.3 6.3 7.7 5.8 7.6 7.9 6.1 8.2 14.3 1.2 19.7 7.8 5.1 4.4 10.7 2.1 2.6 3.9 1.7 6.6 12.4 6.3 1.4 4.7 9.9 9.0 7.9 2.5 67.2 3.2 1.5 6.4 6.6 3.1 2.9 13.7 11.0 2.8 2.3 4.7 9.7 4.3 3.2 10.2 5.7 5.8 5.8 6.5 3.7 91.9 9.5 9.7 6.4 8.6 2.7 4.3 3.9 5.6 4.6 13.7 0.0 8.0 8.6 1.3 11.3 2.8 0.9 1.1 3.4 4.4 0.9 0.4 0.6 7.6 2.0 10.4 3.3 1.4 2.6 5.4 13.9 3.5 7.6 11.1 6.0 7.5 4.0 16.3 5.5 HYAL3 "LUCA-3, LUCA14, Minna14" ENSG00000186792 "Hyaluronoglucosaminidase 3" O43820 3 50292831-50299468 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 26.9;bone marrow: 48.8;brain: 12.5;testis: 31.1" "Cell line enhanced" "Detected in many" "HEL: 21.9;HMC-1: 39.3;THP-1: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.1;eosinophil: 26.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 26.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049402 Uncertain "Secreted to blood" "HPA049402: " "unprognostic (1.21e-3)" "unprognostic (2.55e-2)" "unprognostic (5.45e-2)" "unprognostic (8.19e-2)" "unprognostic (3.07e-1)" "unprognostic (1.65e-2)" "unprognostic (7.98e-3)" "unprognostic (7.36e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" "unprognostic (5.40e-2)" "unprognostic (5.71e-2)" "unprognostic (2.61e-1)" "unprognostic (8.09e-2)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "prognostic unfavourable (2.12e-5)" 3.5 4.2 6.3 3.1 8.8 48.8 3.3 11.4 12.5 4.2 3.6 3.8 6.1 3.8 2.7 5.1 5.6 3.7 5.4 3.4 6.4 5.6 2.9 7.0 3.2 4.2 5.3 5.6 4.3 3.7 2.6 3.1 3.6 11.1 4.9 2.9 3.7 6.7 5.6 3.9 3.0 4.1 4.6 3.4 2.8 6.6 31.1 2.7 3.0 3.3 5.1 3.7 4.8 3.8 1.1 4.2 26.9 2.1 1.0 2.2 1.2 2.2 2.5 1.4 1.6 3.0 1.6 0.9 2.4 2.2 3.1 2.3 3.4 2.3 1.9 1.2 2.8 2.4 2.6 5.7 1.1 4.5 1.3 21.9 6.7 2.8 2.1 2.3 39.3 3.2 4.4 3.1 2.0 3.1 1.6 2.4 1.4 1.3 0.9 13.9 1.1 6.4 0.9 1.9 3.5 3.7 0.9 1.8 2.1 3.5 2.8 1.9 1.9 40.4 4.2 2.6 1.9 8.4 1.4 1.1 2.5 1.5 2.3 8.4 2.2 12.1 2.1 26.9 0.7 1.1 1.2 0.9 2.2 1.0 4.2 1.1 0.6 0.8 0.7 1.0 0.7 1.1 1.3 1.2 6.3 8.8 11.4 12.5 6.4 5.6 5.3 5.6 11.1 2.7 HYAL4 ENSG00000106302 "Hyaluronoglucosaminidase 4" Q2M3T9 7 123828983-123877478 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 7.1;skeletal muscle: 8.3" "Cell line enhanced" "Detected in some" "BEWO: 4.4;CAPAN-2: 7.1;RT4: 16.6" "Cancer enriched" "Detected in single" 48 "testis cancer: 8.4" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA029453 Uncertain "HPA029453: AB_10601432" "unprognostic (5.19e-5)" "unprognostic (4.18e-2)" "unprognostic (4.82e-2)" "unprognostic (2.20e-1)" "unprognostic (4.14e-2)" "unprognostic (2.60e-1)" "unprognostic (8.24e-2)" "unprognostic (5.26e-2)" "unprognostic (8.15e-3)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (5.55e-3)" 0.1 0.3 0.0 0.0 0.0 0.7 0.2 0.0 0.5 0.0 0.1 0.0 0.1 0.4 0.4 0.2 0.0 0.4 0.0 0.0 0.6 0.1 0.4 0.0 0.0 0.1 0.6 0.0 0.1 7.1 0.2 0.0 1.2 0.0 8.3 1.4 0.2 0.0 0.1 1.0 0.2 3.4 0.4 1.5 1.0 0.1 1.3 0.6 3.3 0.6 1.0 0.9 0.1 0.3 0.6 0.1 0.4 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 7.1 0.3 0.3 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 16.6 0.2 0.1 0.0 0.9 0.0 0.4 0.2 2.4 0.1 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.5 0.4 0.6 0.5 0.5 0.4 0.5 0.5 0.2 1.3 0.7 0.9 3.3 1.0 0.6 0.6 0.3 0.1 IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574076 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Intracellular and membrane" 140000 "HPA063478: " "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favourable (3.69e-4)" "prognostic favourable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" 9.8 13.1 6.9 11.7 8.8 6.0 19.8 8.6 9.4 10.5 9.9 6.5 17.5 7.4 10.2 15.9 13.0 8.4 9.6 13.6 5.8 5.3 13.3 21.3 7.9 9.2 8.9 5.1 7.7 15.7 19.4 11.1 9.4 7.6 11.6 10.0 10.5 11.0 17.2 31.1 45.2 10.7 14.3 8.8 9.9 10.3 18.1 7.5 13.5 12.0 13.9 10.7 11.5 9.8 7.4 11.3 3.8 13.7 7.7 10.6 5.5 12.2 18.1 14.1 29.0 13.8 11.6 7.8 10.8 25.7 11.4 9.7 18.4 14.5 17.3 16.0 15.8 15.8 18.6 11.9 7.5 20.7 11.4 8.6 15.1 16.1 12.1 26.2 13.6 8.2 11.6 13.4 19.4 19.2 16.0 12.3 12.9 8.2 8.7 10.3 11.2 7.2 12.1 13.2 11.0 16.8 22.9 6.6 9.2 14.6 10.5 9.5 15.0 7.4 17.8 7.4 8.4 7.7 13.9 11.3 14.1 18.5 10.8 21.0 5.1 2.3 8.2 3.8 6.7 11.4 5.9 7.4 7.9 6.5 11.3 5.3 6.0 6.4 0.5 7.7 13.7 4.4 10.6 5.5 6.9 8.8 8.6 9.4 5.8 5.3 8.9 5.1 7.6 7.5 IDS SIDS ENSG00000010404 "Iduronate 2-sulfatase" P22304 X 149476990-149521096 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 107.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA078003 Approved "Intracellular and membrane" 8900000 "HPA078003: " "unprognostic (9.88e-2)" "unprognostic (1.10e-2)" "unprognostic (6.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (4.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-1)" "unprognostic (9.76e-3)" "unprognostic (3.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" 11.6 20.4 92.9 12.1 81.5 16.0 12.0 30.4 107.9 13.1 9.3 15.0 8.1 9.1 17.8 29.5 11.3 14.8 12.3 16.2 83.6 42.7 10.5 7.0 17.9 12.5 36.7 51.8 22.6 10.6 19.5 17.8 7.4 33.0 14.0 10.7 7.7 9.1 19.5 8.9 12.9 11.6 14.1 21.0 14.1 10.6 3.8 14.7 1.9 13.2 4.9 14.7 11.4 8.6 8.7 11.7 63.4 16.6 8.5 18.2 13.3 14.3 16.3 7.2 4.2 7.9 14.1 3.0 8.3 21.8 7.7 14.8 3.3 10.8 34.5 22.2 12.3 8.4 6.9 13.0 10.0 12.4 5.9 3.7 5.3 1.9 6.1 5.9 33.3 7.7 7.0 16.7 11.0 12.2 1.7 25.2 11.4 18.3 5.9 3.1 5.6 11.2 3.9 6.5 6.6 9.9 3.6 9.6 22.2 3.2 7.4 10.2 2.3 2.6 14.3 10.2 10.4 16.5 22.4 17.7 13.9 25.2 45.9 14.2 7.2 23.9 13.8 39.6 18.2 14.9 13.5 8.7 11.2 13.6 11.7 6.6 7.5 11.3 63.4 8.5 16.6 8.8 16.9 13.3 92.9 81.5 30.4 90.7 83.6 42.7 36.7 51.8 33.0 14.7 IDUA MPS1 ENSG00000127415 "Iduronidase, alpha-L-" P35475 4 986997-1004506 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025901, HPA046979, HPA054254" Enhanced Supported Vesicles "Intracellular and membrane" 130000 Vesicles "CAB025901: , HPA046979: , HPA054254: " "unprognostic (3.62e-2)" "unprognostic (9.08e-2)" "prognostic unfavourable (3.13e-4)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-2)" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-2)" "unprognostic (1.89e-3)" "unprognostic (2.64e-2)" "unprognostic (4.61e-3)" "prognostic unfavourable (7.87e-5)" "unprognostic (2.24e-1)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "prognostic favourable (8.04e-5)" 11.0 15.0 14.7 12.0 15.3 10.8 12.9 36.5 15.7 12.4 9.2 10.9 16.9 17.1 13.0 13.4 7.7 12.1 15.9 8.9 13.4 6.5 13.4 10.7 12.8 11.2 11.6 10.0 14.6 22.6 13.0 15.2 4.0 12.8 14.5 6.0 14.1 20.2 15.8 6.2 16.8 11.8 7.3 9.0 15.3 21.3 4.7 12.6 7.6 14.0 3.4 10.0 10.4 11.2 0.8 4.1 0.0 3.8 3.1 4.5 1.1 3.0 5.7 0.0 2.4 13.2 4.7 8.7 8.3 7.3 2.8 1.7 2.0 9.8 1.3 9.3 5.6 1.9 0.3 1.1 0.6 8.3 0.4 4.9 5.9 0.7 5.5 4.0 13.2 9.0 4.1 2.3 0.0 2.0 2.4 0.1 2.7 3.3 2.7 4.2 1.9 5.4 7.5 0.0 1.4 4.6 6.1 0.1 3.8 0.9 0.0 4.7 6.7 3.4 8.6 15.4 1.7 8.6 2.2 32.0 3.6 1.6 7.5 5.4 3.7 0.0 3.5 0.0 3.3 2.7 4.5 0.6 2.7 2.6 4.1 0.8 3.4 2.0 0.0 3.1 3.8 2.5 1.3 1.1 14.7 15.3 36.5 15.7 13.4 6.5 11.6 10.0 12.8 12.6 IFIH1 "Hlcd, IDDM19, MDA-5, MDA5" ENSG00000115267 "Interferon induced with helicase C domain 1" Q9BYX4 2 162267079-162318703 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.5;BJ hTERT+ SV40 Large T+ RasG12V: 39.2;Karpas-707: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002656 Approved "HPA002656: AB_1079344" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (5.51e-2)" "unprognostic (3.85e-3)" "unprognostic (3.34e-1)" "unprognostic (1.39e-1)" "unprognostic (5.65e-2)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.62e-1)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.41e-2)" "unprognostic (7.29e-2)" 17.2 11.3 5.8 23.1 5.8 26.9 10.5 2.8 6.4 10.3 12.5 4.9 9.5 12.3 7.3 11.0 9.9 8.3 10.8 6.3 6.1 4.7 10.4 11.8 19.7 17.2 6.1 3.2 11.2 11.5 11.6 14.0 15.6 7.0 12.3 7.8 5.9 15.7 17.2 4.7 6.4 18.0 5.8 7.4 25.3 9.0 4.3 4.2 20.5 15.9 8.3 12.9 9.1 10.4 12.3 10.5 14.5 11.6 3.6 9.4 7.1 3.0 0.3 0.1 0.0 4.0 3.1 1.2 0.5 8.4 31.5 39.2 0.5 7.5 6.1 4.6 0.5 3.3 0.5 4.1 3.3 14.5 1.7 3.6 0.5 1.8 3.6 4.0 2.7 2.4 2.7 3.8 0.8 2.4 0.1 18.6 0.5 6.3 4.1 4.0 0.0 1.5 3.0 0.0 8.7 3.6 3.9 0.1 0.0 1.8 10.3 18.0 2.7 3.2 1.9 0.9 0.8 0.4 1.2 7.2 11.8 0.9 1.6 3.2 2.8 4.2 11.0 4.0 6.5 11.6 9.3 11.4 8.3 7.2 10.5 12.3 6.9 7.1 14.5 3.6 11.0 1.5 9.4 7.1 5.8 5.8 2.8 6.4 6.1 4.7 6.1 3.2 7.0 4.2 IGHMBP2 "CATF1, CMT2S, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7" ENSG00000132740 "Immunoglobulin mu binding protein 2" P38935 11 68903842-68940602 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Ribonucleoprotein, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004092, HPA060994" Enhanced Nucleoplasm Nucleoplasm "HPA004092: , HPA060994: " "unprognostic (1.17e-1)" "unprognostic (1.04e-1)" "unprognostic (7.17e-2)" "unprognostic (3.96e-1)" "unprognostic (1.54e-1)" "unprognostic (1.69e-1)" "unprognostic (3.59e-3)" "unprognostic (4.31e-2)" "unprognostic (3.81e-1)" "unprognostic (1.19e-1)" "prognostic favourable (5.89e-4)" "unprognostic (1.03e-1)" "prognostic unfavourable (1.29e-8)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" 7.2 6.0 6.9 8.1 11.0 13.8 9.4 17.7 14.9 8.1 14.6 8.3 14.3 9.7 12.0 5.4 8.8 8.5 7.8 7.7 6.6 5.3 6.7 8.7 7.3 7.9 4.6 7.0 9.4 9.6 7.7 6.0 6.5 6.6 9.0 6.1 7.9 12.7 10.0 12.2 11.7 9.4 8.1 4.1 8.9 9.1 36.9 5.7 10.0 7.3 5.9 8.8 8.8 8.3 5.0 3.3 4.7 12.1 2.7 5.1 2.7 8.0 9.2 5.5 8.8 4.5 3.5 8.4 8.0 5.0 10.0 6.6 18.7 8.0 7.0 11.4 4.1 12.8 9.2 5.0 4.2 8.2 7.8 10.0 10.9 6.0 5.2 7.5 9.5 2.6 6.0 10.6 5.4 5.1 11.7 9.0 3.4 6.3 11.9 13.5 4.8 9.8 9.9 8.4 8.5 4.7 7.3 8.8 6.4 9.5 8.2 19.0 12.6 5.7 6.9 8.6 7.5 11.5 8.3 10.1 7.7 8.1 6.0 7.3 7.8 0.0 3.9 2.2 5.1 3.3 4.7 5.0 3.4 4.0 3.3 3.3 2.4 3.3 4.7 2.7 12.1 2.5 4.0 2.7 6.9 11.0 17.7 14.9 6.6 5.3 4.6 7.0 6.6 5.7 ILKAP "DKFZP434J2031, FLJ10181, PPM1O" ENSG00000132323 "ILK associated serine/threonine phosphatase" Q9H0C8 2 238170401-238203729 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004752, HPA056099" Uncertain Supported Nucleoplasm Nucleoplasm "HPA004752: AB_1851753, HPA056099: " "unprognostic (1.50e-1)" "unprognostic (1.62e-1)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "unprognostic (9.75e-2)" "prognostic unfavourable (1.04e-4)" "unprognostic (1.60e-1)" "unprognostic (3.07e-2)" "unprognostic (3.88e-2)" "unprognostic (1.37e-3)" "unprognostic (7.03e-2)" "prognostic unfavourable (9.89e-6)" "unprognostic (6.24e-2)" "unprognostic (6.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-1)" 17.0 17.1 19.4 31.3 22.2 34.6 24.2 34.1 23.4 18.7 23.4 29.5 22.0 20.5 23.0 22.7 19.4 19.0 21.8 20.9 20.6 19.8 17.8 20.8 27.1 25.7 23.9 21.4 22.1 24.1 17.5 24.7 18.1 22.7 21.5 18.9 20.2 19.0 24.9 32.8 19.4 19.0 26.5 19.8 22.2 18.1 21.2 25.5 23.9 22.6 19.0 24.8 18.1 26.1 18.9 20.7 24.1 18.1 17.4 23.8 16.2 17.7 11.6 17.1 16.7 13.3 8.9 17.5 18.8 12.8 19.0 16.6 10.7 9.5 11.4 4.9 13.6 15.2 22.1 15.6 19.4 20.2 21.9 29.4 11.4 23.5 20.6 18.8 23.3 9.3 10.8 20.2 20.4 14.2 22.6 7.4 16.2 21.3 18.9 25.6 15.9 11.1 23.1 34.9 10.4 14.0 8.5 25.2 12.4 12.7 13.7 30.0 10.7 19.6 12.8 18.6 16.9 24.9 19.9 13.2 13.2 20.5 15.2 21.1 15.7 24.1 15.1 19.6 22.5 18.1 20.1 18.9 20.0 21.0 20.7 18.5 23.8 18.6 5.3 17.4 15.1 15.8 22.4 16.2 19.4 22.2 34.1 23.4 20.6 19.8 23.9 21.4 22.7 25.5 IMPA1 IMPA ENSG00000133731 "Inositol monophosphatase 1" P29218 8 81657961-81686693 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037489 Approved Approved Nucleoplasm,Mitochondria 390000 Mitochondria Nucleoplasm "HPA037489: AB_10671757" "unprognostic (1.78e-1)" "unprognostic (3.59e-2)" "unprognostic (6.95e-3)" "unprognostic (2.15e-3)" "unprognostic (1.31e-1)" "unprognostic (6.27e-2)" "unprognostic (3.80e-1)" "unprognostic (2.46e-2)" "unprognostic (1.06e-1)" "unprognostic (4.68e-2)" "unprognostic (7.78e-2)" "unprognostic (6.26e-2)" "unprognostic (2.52e-2)" "unprognostic (5.87e-2)" "unprognostic (1.84e-1)" "unprognostic (2.42e-1)" "unprognostic (5.41e-3)" 10.8 10.9 16.2 10.5 20.9 20.8 9.2 11.2 29.7 9.4 22.4 15.3 4.7 20.1 10.8 12.0 17.2 10.3 11.0 22.3 17.6 19.7 25.5 29.4 9.8 14.3 18.9 20.7 12.1 8.5 8.6 20.1 7.2 27.3 10.6 25.4 14.8 8.9 7.3 11.2 5.0 23.5 15.0 19.1 12.9 12.2 30.5 13.8 16.2 20.3 12.0 13.7 10.5 10.7 13.2 8.2 24.1 7.5 13.6 12.9 7.2 5.7 15.8 11.0 8.3 6.4 10.2 4.5 16.6 12.0 14.9 18.0 7.4 9.1 21.8 13.3 11.8 4.4 12.7 5.7 20.1 22.8 13.0 16.4 8.7 9.2 11.6 16.4 16.8 9.7 8.3 11.4 22.6 16.2 14.8 18.5 14.9 3.6 20.8 9.5 4.7 16.9 9.8 8.3 8.9 17.2 18.6 4.5 19.0 10.9 2.9 19.9 9.5 13.2 12.5 12.3 15.7 9.5 20.5 21.7 25.8 30.5 14.3 9.9 16.8 24.1 4.7 19.5 9.9 6.6 12.1 13.2 10.1 10.7 5.0 9.5 10.7 12.6 7.5 13.6 7.5 8.2 12.9 7.2 16.2 20.9 11.2 29.7 17.6 19.7 18.9 20.7 27.3 13.8 IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030883 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 90.1" "Cell line enhanced" "Detected in many" "BEWO: 67.4;RPTEC TERT1: 32.6;SiHa: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 14.4;neutrophil: 18.7" "Group enriched" "Detected in many" 14 "dendritic cells: 5.3;granulocytes: 18.7;monocytes: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029561 Approved Approved Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA029561: AB_10601932" "unprognostic (1.16e-1)" "unprognostic (1.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.50e-2)" "unprognostic (4.25e-2)" "unprognostic (3.25e-3)" "unprognostic (4.26e-3)" "unprognostic (4.08e-2)" "unprognostic (1.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.56e-2)" "unprognostic (4.24e-3)" "prognostic favourable (0.00e+0)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (3.35e-2)" 6.2 2.8 1.5 5.2 1.9 6.9 10.7 0.3 1.5 6.8 12.2 0.7 1.6 5.6 7.3 3.0 40.3 4.1 17.5 20.1 1.4 0.5 41.3 21.0 6.5 4.6 2.2 0.3 3.1 90.1 1.0 5.7 35.6 1.3 17.5 7.8 3.4 9.8 2.5 55.0 30.4 9.2 40.0 1.4 4.8 13.5 1.5 2.0 3.1 8.0 31.4 10.3 22.6 14.7 0.7 5.3 18.7 6.8 0.1 0.6 1.8 6.9 10.8 2.9 5.2 3.8 2.8 67.4 1.8 4.8 0.8 1.1 8.6 5.6 1.5 4.3 2.6 4.8 3.4 1.8 0.2 8.2 4.2 0.0 14.2 7.4 2.2 11.9 0.6 6.4 9.7 2.6 1.3 1.0 1.7 0.0 2.8 7.0 4.8 6.3 10.2 8.2 8.2 8.1 7.1 32.6 3.9 3.9 0.0 40.7 9.2 3.9 8.7 14.9 0.0 1.5 2.8 19.9 1.8 5.6 14.8 4.1 6.4 8.0 2.5 3.3 6.8 14.4 0.4 4.9 0.2 0.7 0.4 0.1 5.3 0.2 0.2 0.3 18.7 0.1 3.0 3.7 0.6 1.8 1.5 1.9 0.3 1.5 1.4 0.5 2.2 0.3 1.3 2.0 IMPAD1 "FLJ20421, gPAPP, IMPA3" ENSG00000104331 "Inositol monophosphatase domain containing 1" Q9NX62 8 56957933-56993844 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" 560000 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 30.6 33.9 17.8 13.9 23.7 9.6 17.6 23.6 33.1 24.7 17.7 30.9 17.8 11.7 23.2 15.2 17.7 15.6 18.0 25.2 19.9 21.6 21.3 32.6 16.5 10.3 23.6 21.1 16.0 25.2 30.4 20.4 23.3 27.2 28.8 16.2 25.2 28.7 22.5 41.4 13.4 12.3 23.0 21.7 13.0 14.7 19.0 19.5 12.0 24.4 18.1 13.0 17.2 14.9 1.9 2.0 6.1 4.6 6.8 2.4 0.6 17.1 14.3 11.0 11.3 33.9 23.3 15.2 26.1 25.4 18.7 16.4 7.1 12.2 10.7 20.0 27.7 14.1 13.3 17.6 27.9 14.7 9.5 20.9 10.1 12.7 21.1 13.2 14.9 18.7 17.7 16.8 27.4 24.8 9.0 19.5 20.5 9.1 16.1 8.0 8.2 5.3 11.3 9.9 12.1 19.5 10.2 4.3 12.0 14.6 18.1 14.8 16.1 9.7 20.7 25.4 14.7 25.0 18.7 20.2 16.8 11.5 34.8 11.1 15.6 2.9 1.9 1.1 2.0 1.2 1.6 1.3 1.3 1.2 1.4 1.9 1.5 2.4 6.1 6.8 4.6 2.0 0.9 0.6 17.8 23.7 23.6 33.1 19.9 21.6 23.6 21.1 27.2 19.5 INO80 "hINO80, Ino80, INO80A, INOC1, KIAA1259" ENSG00000128908 "INO80 complex subunit" Q9ULG1 15 40978880-41116354 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis" "Actin-binding, DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041417, HPA041484" Enhanced "Nucleoplasm,Nuclear bodies" "Nucleoplasm, Nuclear bodies" "HPA041417: , HPA041484: " "unprognostic (5.39e-3)" "unprognostic (2.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (3.92e-2)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (1.93e-1)" "unprognostic (6.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.69e-2)" "prognostic favourable (6.30e-4)" "unprognostic (1.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.72e-2)" "unprognostic (1.47e-2)" 14.0 10.6 11.8 13.9 13.4 20.7 13.9 29.5 13.0 12.3 13.2 17.4 11.5 11.3 14.9 13.4 15.1 12.6 12.4 10.6 12.8 7.8 12.1 12.9 14.8 13.4 10.2 10.3 15.4 17.8 18.8 13.3 16.4 12.1 12.5 13.9 13.8 11.9 15.7 23.0 16.4 13.2 13.3 9.5 14.5 12.3 13.9 11.6 18.1 13.3 12.6 15.8 13.9 13.3 5.2 2.3 0.9 2.7 5.7 3.4 1.5 9.1 9.1 7.9 7.7 12.5 10.5 9.2 8.5 14.0 13.0 11.3 11.1 7.7 9.8 6.9 13.0 18.0 14.5 14.9 13.8 11.3 7.5 12.2 12.7 8.4 12.0 12.0 12.0 10.4 13.8 10.4 27.7 12.4 13.6 8.5 8.7 7.6 8.7 8.0 8.3 10.0 13.5 8.4 7.9 9.8 19.3 10.6 7.2 6.2 13.8 5.8 7.8 14.6 14.2 10.3 9.4 13.1 13.7 9.4 6.4 16.0 12.2 17.8 8.5 0.9 2.7 0.6 2.7 1.7 3.3 3.2 3.4 3.0 2.3 5.2 3.4 3.2 0.9 5.7 1.2 1.8 2.6 1.5 11.8 13.4 29.5 13.0 12.8 7.8 10.2 10.3 12.1 11.6 INPP1 ENSG00000151689 "Inositol polyphosphate-1-phosphatase" P49441 2 190343470-190371665 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "eosinophil: 36.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036698, HPA036699" Supported Approved "Centriolar satellite,Cytosol" 15000 "Centriolar satellite" Cytosol "HPA036698: AB_10672226, HPA036699: " "unprognostic (1.08e-3)" "unprognostic (4.50e-3)" "unprognostic (3.87e-2)" "unprognostic (2.70e-1)" "unprognostic (7.85e-2)" "unprognostic (3.67e-3)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (2.96e-2)" "unprognostic (7.28e-2)" "unprognostic (2.41e-1)" "unprognostic (2.54e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "prognostic favourable (1.12e-5)" "prognostic favourable (5.70e-4)" 14.9 25.8 18.3 9.1 26.5 10.3 32.5 17.4 25.1 15.0 19.8 20.4 11.5 27.4 12.0 10.8 42.7 9.8 20.6 17.7 21.2 17.9 11.0 24.8 19.9 8.8 21.0 16.5 10.0 25.6 32.3 17.0 10.4 18.6 10.0 16.8 12.0 9.9 16.0 13.1 28.3 28.0 15.5 23.6 15.7 13.9 31.4 17.1 4.6 12.9 14.0 15.4 19.2 18.8 1.8 3.5 36.6 3.4 6.2 8.0 1.9 10.8 3.0 5.9 0.0 6.5 14.0 0.1 13.1 17.5 12.3 16.2 11.8 6.9 0.0 15.6 12.5 15.0 2.4 8.4 15.1 13.3 4.6 8.2 9.6 7.0 13.7 6.0 2.6 9.5 13.0 14.0 8.1 22.9 19.4 6.9 21.6 0.0 0.4 5.8 1.7 16.8 0.2 4.8 0.1 9.5 25.9 8.8 3.3 9.0 0.5 12.7 0.0 8.8 21.2 7.9 5.6 14.1 7.6 1.3 1.4 0.1 2.5 2.4 6.2 8.1 3.4 36.6 3.0 3.1 2.7 1.4 1.9 2.0 3.5 1.8 1.0 1.5 1.6 6.2 1.8 0.1 8.0 1.9 18.3 26.5 17.4 25.1 21.2 17.9 21.0 16.5 18.6 17.1 INPP4A INPP4 ENSG00000040933 "Inositol polyphosphate-4-phosphatase type I A" Q96PE3 2 98444854-98594390 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001628 Approved Approved "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA001628: AB_10961254" "unprognostic (3.45e-1)" "unprognostic (2.39e-2)" "unprognostic (1.74e-2)" "prognostic unfavourable (3.70e-6)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "unprognostic (1.15e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (9.65e-2)" "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (4.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" 9.0 15.0 11.4 13.5 23.1 12.3 7.0 24.0 28.4 7.5 8.5 8.3 3.8 7.7 8.2 5.7 8.4 6.7 11.0 10.8 12.9 7.8 8.1 7.2 13.5 17.0 6.1 19.8 8.3 8.2 12.7 7.0 8.6 17.9 6.8 8.6 16.1 9.3 7.2 13.6 7.3 12.1 10.5 10.4 24.0 8.4 6.4 6.8 17.6 8.4 2.7 13.4 16.8 6.9 0.8 5.9 3.8 5.1 5.8 6.4 1.8 6.4 5.4 10.0 8.1 5.8 6.6 10.1 5.7 5.0 6.1 6.2 7.0 5.7 4.2 6.4 8.2 6.0 7.2 5.6 4.9 13.8 6.1 4.8 4.9 3.2 5.2 9.1 17.9 5.9 5.2 5.8 5.1 8.5 4.4 34.5 4.5 7.8 13.9 8.2 9.5 5.4 6.0 7.1 26.9 2.9 20.0 6.6 8.7 6.4 5.3 5.1 2.4 7.3 8.0 7.0 9.0 5.5 3.9 24.5 14.2 2.9 5.8 8.8 6.0 2.0 1.8 3.8 5.5 3.9 6.4 0.8 3.1 3.7 1.9 0.2 4.3 4.9 2.0 5.8 5.1 5.9 1.6 1.8 11.4 23.1 24.0 28.4 12.9 7.8 6.1 19.8 17.9 6.8 INPP4B ENSG00000109452 "Inositol polyphosphate-4-phosphatase type II B" O15327 4 142023160-142847432 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 51.5;SK-MEL-30: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "memory CD4 T-cell: 19.2" "Group enriched" "Detected in many" 6 "NK-cells: 9.1;T-cells: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037681, HPA037682" Approved Approved Centrosome Centrosome "HPA037681: AB_10670389, HPA037682: AB_10671377" "unprognostic (9.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.25e-2)" "unprognostic (1.77e-1)" "unprognostic (8.24e-2)" "unprognostic (3.03e-3)" "unprognostic (5.76e-3)" "unprognostic (1.95e-2)" "unprognostic (3.16e-1)" "prognostic unfavourable (1.03e-4)" "unprognostic (8.58e-2)" "unprognostic (1.26e-2)" "unprognostic (2.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.58e-1)" "unprognostic (1.39e-2)" 15.4 4.7 8.4 8.5 12.5 2.2 21.2 5.1 10.3 28.1 7.1 1.8 5.6 5.0 19.7 18.4 9.1 9.2 8.7 18.4 5.9 6.1 6.1 2.0 9.9 10.8 5.5 8.9 15.4 4.0 2.3 3.8 6.2 4.6 8.3 5.8 1.7 4.9 6.8 10.8 4.7 7.3 10.2 3.1 7.0 7.0 19.6 2.4 8.2 6.5 4.9 7.4 15.8 14.6 0.0 0.0 2.2 0.1 9.1 19.2 3.7 9.1 3.8 2.5 1.2 1.9 1.2 0.5 11.1 13.0 2.8 5.4 1.0 51.5 0.2 3.1 9.9 14.0 0.0 12.9 6.7 0.0 0.3 2.2 1.4 0.0 0.6 0.4 1.7 2.1 1.8 2.0 6.8 1.6 0.0 0.5 6.1 16.3 0.3 0.0 0.1 2.8 0.1 8.6 0.4 3.9 17.0 0.2 0.2 1.2 3.9 22.9 11.8 1.6 1.0 6.6 8.1 9.7 0.1 0.1 0.0 0.0 1.5 10.0 17.0 2.2 0.1 0.0 3.3 0.0 6.5 0.0 19.2 8.5 0.0 0.0 13.2 5.7 0.2 9.1 0.0 0.0 9.8 3.7 8.4 12.5 5.1 10.3 5.9 6.1 5.5 8.9 4.6 2.4 INPP5A 5PTASE ENSG00000068383 "Inositol polyphosphate-5-phosphatase A" Q14642 10 132537820-132783480 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 8.4" "Lineage enriched" "Detected in single" 21 "granulocytes: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012285, HPA066549" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" "Endoplasmic reticulum" "HPA012285: AB_1851802, HPA066549: " "prognostic unfavourable (7.47e-4)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (1.68e-3)" "unprognostic (1.43e-1)" "unprognostic (3.25e-2)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (5.65e-2)" "unprognostic (4.35e-1)" "unprognostic (4.70e-2)" "unprognostic (1.70e-2)" "prognostic favourable (3.15e-4)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (8.91e-3)" "unprognostic (8.66e-2)" 13.6 11.8 10.3 11.3 49.8 5.8 10.3 40.7 20.8 17.4 24.0 10.1 11.5 12.9 25.8 13.9 20.3 15.2 13.6 48.8 9.5 8.5 9.4 7.2 13.8 6.0 9.2 10.4 13.1 11.6 8.9 9.4 19.0 9.1 17.1 11.7 17.1 8.5 16.9 43.7 11.5 14.8 27.9 10.6 8.9 14.8 14.9 16.6 4.2 9.5 12.1 7.8 19.4 22.4 0.3 0.1 8.4 0.2 0.0 0.3 0.6 18.4 7.4 12.4 11.9 18.9 13.4 10.1 19.6 15.1 12.8 8.6 17.4 7.6 1.6 7.6 20.7 10.5 13.4 8.2 15.4 5.6 7.8 2.7 9.2 23.6 13.8 6.7 6.5 9.0 8.2 8.2 15.7 8.8 3.9 9.9 6.8 15.0 1.9 21.6 5.6 13.2 3.9 8.2 2.9 10.7 10.6 2.9 10.1 9.8 14.5 11.8 9.3 16.2 7.4 8.3 9.6 11.0 11.4 2.0 9.2 5.7 8.0 4.6 3.5 8.4 0.2 1.1 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.0 1.5 0.0 0.2 0.0 0.3 0.6 10.3 49.8 40.7 20.8 9.5 8.5 9.2 10.4 9.1 16.6 INPP5B ENSG00000204084 "Inositol polyphosphate-5-phosphatase B" P32019 1 37860697-37947057 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028803 Approved Approved Cytosol Cytosol "HPA028803: AB_10612121" "unprognostic (2.28e-2)" "unprognostic (8.91e-3)" "unprognostic (7.67e-2)" "unprognostic (2.27e-1)" "unprognostic (4.30e-2)" "prognostic favourable (1.11e-4)" "unprognostic (1.67e-2)" "unprognostic (1.52e-2)" "unprognostic (4.75e-2)" "unprognostic (1.85e-1)" "prognostic favourable (5.33e-4)" "unprognostic (8.27e-2)" "prognostic unfavourable (6.11e-5)" "unprognostic (1.03e-1)" "unprognostic (2.00e-1)" "unprognostic (2.51e-1)" "unprognostic (1.28e-1)" 14.5 10.2 11.7 15.9 18.2 22.3 12.8 25.4 16.1 15.3 18.3 21.0 9.4 9.3 19.5 13.7 9.9 15.0 13.7 14.3 12.2 9.0 11.7 16.2 18.7 21.1 23.2 11.4 28.7 11.4 13.1 14.4 14.3 15.9 12.0 13.7 18.9 9.4 16.0 9.7 12.0 13.9 17.5 18.5 19.0 14.7 8.6 21.8 17.4 13.8 4.7 22.3 17.4 13.2 6.7 5.3 19.1 4.7 5.3 9.1 3.8 3.7 2.8 6.6 10.5 8.2 10.6 11.6 4.6 8.1 5.8 8.4 4.3 5.6 13.8 2.2 8.4 5.1 8.6 3.3 7.7 8.9 3.8 21.0 9.0 2.8 12.0 11.1 30.5 12.4 2.1 6.1 3.9 7.0 7.1 18.0 8.0 3.2 8.9 11.8 9.2 2.2 10.9 13.0 6.5 3.4 3.4 2.6 4.5 4.9 2.3 12.0 2.9 9.8 6.9 5.9 5.5 5.5 4.2 14.7 7.1 11.1 7.0 10.4 5.0 19.1 2.5 13.2 6.3 2.0 9.1 6.5 4.5 6.1 5.3 6.7 5.8 5.3 3.4 5.3 4.7 4.8 5.6 3.8 11.7 18.2 25.4 16.1 12.2 9.0 23.2 11.4 15.9 21.8 INPP5D "hp51CN, SHIP, SHIP1" ENSG00000168918 "Inositol polyphosphate-5-phosphatase D" Q92835 2 233059967-233207903 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.9" "Cell line enhanced" "Detected in many" "HEL: 31.2;HMC-1: 32.8;hTCEpi: 30.0;NB-4: 29.3;THP-1: 20.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016300, HPA070455" Enhanced Approved Cytosol Cytosol "CAB016300: AB_628250, HPA070455: " "unprognostic (5.29e-2)" "unprognostic (2.05e-3)" "unprognostic (1.99e-2)" "unprognostic (6.71e-3)" "unprognostic (1.10e-1)" "prognostic favourable (2.03e-5)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" "unprognostic (3.74e-1)" "unprognostic (2.56e-1)" "unprognostic (1.23e-1)" "unprognostic (1.14e-2)" "unprognostic (1.66e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (6.54e-2)" 7.1 3.1 7.2 33.0 10.7 24.6 4.7 1.7 6.9 3.6 3.7 12.5 0.7 3.5 4.1 2.9 3.3 3.3 6.7 3.2 6.6 9.1 5.1 3.3 8.0 26.1 8.8 2.6 1.9 2.1 1.6 3.4 7.4 7.6 4.5 4.5 3.3 18.8 3.0 1.9 3.4 15.8 3.4 17.6 40.9 4.1 2.4 9.5 16.7 3.1 3.4 32.3 6.2 3.5 14.5 12.0 10.5 18.2 11.9 16.7 14.0 0.0 0.0 0.2 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.4 5.9 0.0 0.0 0.0 0.0 15.1 0.0 5.0 0.0 31.2 0.0 2.9 0.2 9.4 32.8 0.6 30.0 0.1 3.3 4.3 0.1 2.7 0.1 0.0 4.3 29.3 1.0 0.0 9.1 0.0 2.1 0.0 1.8 0.0 0.0 0.0 0.5 0.0 0.0 20.9 3.6 0.0 0.5 0.0 0.0 0.0 1.6 9.0 0.0 12.1 0.0 9.8 9.8 10.5 16.7 15.8 11.4 14.5 7.5 12.3 12.0 13.9 6.3 8.8 9.9 11.9 18.2 6.0 10.2 14.0 7.2 10.7 1.7 6.9 6.6 9.1 8.8 2.6 7.6 9.5 INPP5E "CORS1, JBTS1, pharbin, PPI5PIV" ENSG00000148384 "Inositol polyphosphate-5-phosphatase E" Q9NRR6 9 136428619-136439823 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Ciliopathy, Disease mutation, Joubert syndrome, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065758 Approved "HPA065758: " "unprognostic (1.99e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-2)" "unprognostic (1.23e-2)" "unprognostic (4.00e-1)" "unprognostic (6.92e-2)" "unprognostic (9.60e-3)" "unprognostic (3.21e-1)" "unprognostic (5.81e-2)" "unprognostic (2.65e-2)" "prognostic favourable (1.82e-4)" "unprognostic (2.03e-1)" "unprognostic (3.04e-2)" "unprognostic (3.76e-1)" "unprognostic (5.48e-2)" "unprognostic (4.64e-1)" "unprognostic (2.66e-2)" 14.3 11.2 14.9 15.3 10.4 8.9 19.2 19.9 19.1 10.5 10.7 11.5 11.1 10.3 13.1 10.1 8.4 17.2 9.4 11.9 12.6 12.0 10.2 9.0 10.1 13.5 8.4 12.3 14.7 11.6 11.4 12.3 9.8 13.2 9.9 5.2 11.0 14.4 12.9 11.6 18.2 10.7 10.7 6.6 19.4 8.6 15.2 10.3 8.5 12.5 6.2 10.7 8.8 19.3 2.6 1.0 1.9 0.5 0.0 2.4 0.6 6.1 7.1 8.3 8.2 4.2 5.5 10.3 7.3 4.3 5.7 3.6 7.2 4.3 7.6 7.6 6.1 17.2 3.7 5.1 2.2 23.9 14.4 5.1 12.2 4.8 7.2 6.0 8.3 5.9 4.7 6.3 5.6 5.5 8.6 7.0 4.8 10.1 7.6 13.2 5.4 11.8 14.1 6.4 5.7 5.1 6.0 8.8 7.8 7.1 6.7 5.1 10.7 8.9 7.9 17.6 6.6 7.1 12.8 7.6 6.1 3.2 9.0 5.3 6.4 0.0 0.5 1.9 2.0 0.0 1.3 2.6 2.3 1.5 0.5 1.7 0.8 1.6 0.4 0.0 0.3 1.0 2.4 0.6 14.9 10.4 19.9 19.1 12.6 12.0 8.4 12.3 13.2 10.3 INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726097-119829278 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 69.7" "Cell line enhanced" "Detected in many" "AF22: 36.0;SH-SY5Y: 28.5;SK-MEL-30: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" 4.6 12.3 17.5 5.9 50.4 3.2 5.7 37.0 52.9 10.9 5.0 5.5 2.2 3.1 11.8 18.0 4.5 4.2 5.5 4.1 24.6 53.1 7.3 2.0 4.2 7.6 23.7 29.1 9.8 4.6 8.9 34.0 8.2 69.7 8.3 6.1 3.4 7.1 8.4 7.5 10.4 3.8 10.8 19.2 4.1 3.8 10.1 7.3 1.4 8.4 1.4 9.3 5.3 4.5 12.2 7.4 1.5 4.5 3.8 6.7 2.2 4.6 3.3 36.0 5.2 3.9 4.0 3.1 6.5 3.6 3.1 3.0 4.8 5.9 3.0 2.5 8.1 5.2 3.9 3.8 4.7 1.9 3.6 2.0 1.6 4.8 5.5 1.3 6.7 4.8 3.5 6.1 6.1 10.4 1.8 4.8 7.3 2.6 1.8 5.4 3.4 4.1 2.4 6.4 0.8 5.2 2.4 2.6 28.5 7.2 2.2 54.3 1.5 1.4 6.9 3.1 4.1 4.0 6.3 5.4 2.4 1.4 3.9 4.6 12.6 1.1 4.0 1.5 1.3 3.5 1.6 8.1 2.8 1.9 7.4 12.2 3.2 1.4 1.0 3.8 4.5 1.8 6.7 2.2 17.5 50.4 37.0 50.5 24.6 53.1 23.7 29.1 69.7 7.3 INPP5J "INPP5, PIB5PA, PIPP" ENSG00000185133 "Inositol polyphosphate-5-phosphatase J" Q15735 22 31122731-31134696 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 65.2;thyroid gland: 71.2" "Cell line enhanced" "Detected in many" "HL-60: 12.1;SK-BR-3: 26.2;T-47d: 16.5;U-698: 11.4" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 63.1" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 2.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034539 Approved Nucleoli,Cytosol Cytosol Nucleoli "HPA034539: AB_10670974" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-2)" "unprognostic (2.21e-3)" "prognostic favourable (1.47e-5)" "unprognostic (6.81e-2)" "unprognostic (1.86e-2)" "unprognostic (4.29e-4)" "unprognostic (1.47e-1)" "prognostic favourable (1.12e-7)" "unprognostic (2.79e-3)" "unprognostic (3.65e-2)" "unprognostic (2.14e-1)" "unprognostic (1.39e-2)" 0.8 0.9 4.6 0.8 6.3 0.5 3.7 27.4 13.4 1.5 6.4 0.8 16.7 7.9 1.3 0.8 1.0 1.0 1.0 9.5 7.4 2.0 9.5 0.5 1.5 0.7 2.3 4.6 0.8 5.3 65.2 3.7 0.5 5.5 3.5 2.2 5.6 15.5 19.2 1.6 1.7 21.7 1.2 0.9 0.6 3.8 1.6 1.1 0.0 71.2 0.0 0.7 1.1 0.9 0.3 2.4 0.0 0.4 0.0 0.0 0.2 1.3 1.3 0.8 1.4 0.2 0.1 0.7 0.5 0.5 2.6 2.6 0.7 0.8 0.0 0.6 0.2 1.5 1.6 0.7 1.1 0.0 4.2 0.0 5.5 0.2 0.5 12.1 0.1 0.1 0.8 2.2 0.2 0.1 1.1 1.8 0.0 4.0 0.1 0.0 1.4 0.2 0.0 0.3 2.8 1.1 1.6 6.4 4.8 1.0 26.2 0.3 16.5 1.0 0.0 0.1 4.8 0.5 0.3 0.0 2.0 11.4 0.4 0.0 2.0 0.0 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.2 4.6 6.3 27.4 13.4 7.4 2.0 2.3 4.6 5.5 1.1 INPP5K SKIP ENSG00000132376 "Inositol polyphosphate-5-phosphatase K" Q9BT40 17 1494571-1516888 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Congenital muscular dystrophy, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 114.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (7.47e-2)" "prognostic favourable (3.91e-4)" "unprognostic (8.91e-2)" "prognostic favourable (2.33e-5)" "unprognostic (3.25e-1)" "unprognostic (9.22e-2)" "unprognostic (1.50e-1)" "unprognostic (7.50e-2)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic favourable (1.47e-6)" "unprognostic (4.71e-2)" "unprognostic (9.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.20e-2)" "unprognostic (4.28e-3)" "unprognostic (1.04e-1)" 27.9 10.5 12.7 13.8 13.5 25.9 37.0 14.9 17.7 13.4 13.4 14.9 9.8 9.1 12.8 12.2 12.0 10.4 12.9 17.5 12.8 12.6 11.6 10.5 20.8 14.3 12.8 12.0 14.3 18.9 12.0 10.8 15.9 21.2 13.5 11.4 114.9 12.9 12.2 26.4 22.3 13.9 10.9 10.7 16.2 12.8 20.8 11.3 22.1 27.3 13.8 16.4 12.5 14.1 12.1 16.5 36.4 27.0 17.0 30.8 24.6 9.4 13.1 5.4 10.3 14.0 7.8 8.0 7.9 13.4 9.0 11.5 8.1 5.6 8.4 15.2 12.1 12.4 12.8 5.1 9.3 21.8 21.6 5.2 10.0 3.2 17.7 4.9 10.2 9.2 13.7 9.0 8.9 14.3 5.7 15.2 5.9 6.7 14.9 4.0 2.3 8.9 11.5 4.2 8.0 7.3 5.8 4.2 10.8 6.2 12.2 14.1 10.3 4.0 10.1 7.9 8.1 11.4 10.2 8.0 13.4 4.5 8.9 5.1 9.9 36.4 19.9 31.9 22.2 18.7 18.2 12.1 20.7 22.4 16.5 11.3 17.7 18.9 33.3 17.0 27.0 11.9 30.8 24.6 12.7 13.5 14.9 17.7 12.8 12.6 12.8 12.0 21.2 11.3 INPPL1 SHIP2 ENSG00000165458 "Inositol polyphosphate phosphatase like 1" O15357 11 72223701-72239105 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Immunity" "Actin-binding, Hydrolase" "Cancer-related genes, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037601 Approved Supported "Golgi apparatus,Cytosol" "Golgi apparatus, Cytosol" "HPA037601: AB_10672281" "unprognostic (2.68e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.68e-3)" "unprognostic (1.58e-1)" "prognostic unfavourable (7.37e-4)" "unprognostic (2.49e-2)" "unprognostic (3.54e-2)" "unprognostic (1.51e-2)" "unprognostic (1.64e-1)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (2.88e-1)" "unprognostic (1.99e-3)" "unprognostic (2.07e-1)" 20.9 23.7 22.2 20.4 19.5 25.1 18.6 11.1 18.9 25.2 32.0 22.7 28.8 19.8 24.7 18.4 17.4 24.3 29.6 29.5 24.1 10.3 23.9 17.1 24.9 19.0 27.6 10.4 30.1 22.7 21.6 26.9 31.9 20.4 28.7 13.5 30.7 27.5 24.2 60.0 17.7 23.0 34.7 27.5 28.3 24.5 11.8 24.3 16.0 29.1 19.3 18.3 25.0 18.1 2.6 5.2 7.0 7.6 4.2 4.5 3.3 6.4 13.8 16.6 11.3 8.2 9.8 29.6 29.8 13.9 18.7 11.9 18.9 16.3 18.4 30.5 22.8 24.6 13.6 8.4 6.4 23.8 14.2 19.1 70.0 6.9 16.1 12.6 42.8 13.9 8.9 18.1 7.2 10.0 13.4 7.9 10.2 17.4 9.3 51.0 16.9 21.6 43.9 37.7 4.1 21.7 10.8 8.1 11.8 32.0 19.3 41.6 20.4 23.9 16.9 20.1 23.5 30.7 9.7 22.9 3.8 17.9 5.7 12.0 10.8 5.2 7.6 7.0 4.5 4.4 3.7 2.2 3.7 3.0 5.2 2.6 2.7 3.7 5.2 4.2 7.0 3.9 3.3 3.3 22.2 19.5 11.1 18.9 24.1 10.3 27.6 10.4 20.4 24.3 ISG20 "CD25, HEM45" ENSG00000172183 "Interferon stimulated exonuclease gene 20" Q96AZ6 15 88636153-88656483 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 116.8;lymphoid tissue: 56.6" "Cell line enhanced" "Detected in many" "Daudi: 35.8;Karpas-707: 21.2;SK-MEL-30: 119.1;U-698: 21.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "unprognostic (2.55e-3)" "unprognostic (1.19e-3)" "unprognostic (2.00e-2)" "unprognostic (1.32e-1)" "prognostic unfavourable (6.51e-5)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (4.54e-2)" "unprognostic (1.35e-3)" "prognostic favourable (1.85e-5)" "unprognostic (5.60e-2)" "unprognostic (2.07e-1)" "prognostic unfavourable (4.86e-8)" "unprognostic (1.04e-1)" "unprognostic (4.69e-2)" "unprognostic (3.39e-1)" "unprognostic (1.58e-2)" 8.4 2.4 2.2 39.6 3.6 12.1 7.3 0.8 3.1 4.1 18.3 1.9 8.3 25.9 2.7 8.2 9.9 3.9 36.6 4.9 2.4 2.6 6.1 9.9 26.0 56.6 3.2 1.8 6.8 6.4 0.2 10.1 4.6 3.2 6.0 3.0 2.2 13.2 8.1 4.1 3.4 39.4 1.2 3.6 53.8 21.9 2.5 1.8 29.1 14.5 6.1 41.4 10.7 4.2 99.2 12.3 116.8 5.1 31.0 104.4 29.7 1.5 2.4 0.0 0.0 0.0 0.0 0.4 0.0 1.1 7.4 10.1 0.7 3.5 35.8 1.8 0.1 0.5 0.1 0.8 0.2 11.3 0.1 0.1 1.2 1.5 4.9 0.0 0.0 0.6 1.4 2.5 1.6 1.1 0.1 21.2 0.0 2.6 0.1 0.2 0.3 5.4 1.4 0.1 6.6 0.5 0.3 0.1 0.1 0.2 14.2 119.1 0.4 0.8 1.4 0.2 0.8 0.0 0.5 15.1 4.0 21.3 0.3 0.5 1.5 8.4 3.0 6.2 27.7 5.1 36.6 94.6 47.9 39.7 2.6 99.2 35.5 37.2 116.8 31.0 3.8 12.3 104.4 29.7 2.2 3.6 0.8 3.1 2.4 2.6 3.2 1.8 3.2 1.8 ITPA "C20orf37, dJ794I6.3, HLC14-06-P" ENSG00000125877 "Inosine triphosphatase" Q9BY32 20 3208868-3223870 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022824, HPA073963" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" 69000 Cytosol "Nucleoplasm, Nuclear bodies" "HPA022824: AB_1851960, HPA073963: " "unprognostic (1.58e-2)" "unprognostic (1.98e-1)" "unprognostic (1.73e-1)" "unprognostic (3.57e-1)" "unprognostic (4.63e-2)" "unprognostic (1.53e-2)" "prognostic unfavourable (2.54e-5)" "unprognostic (1.11e-2)" "unprognostic (1.68e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-1)" "unprognostic (1.94e-2)" "unprognostic (8.34e-2)" "unprognostic (3.63e-1)" "unprognostic (1.24e-1)" "unprognostic (1.84e-1)" 17.7 27.5 18.6 24.7 21.2 20.4 17.7 10.2 22.7 21.3 21.4 18.3 20.6 22.9 18.1 17.3 31.0 26.6 19.6 25.9 18.1 13.5 22.9 20.3 22.7 30.6 20.5 24.1 16.5 43.8 17.6 10.2 17.0 16.2 14.6 16.8 13.2 19.9 21.5 19.5 23.4 19.0 16.3 16.3 20.6 19.3 16.7 19.5 15.2 24.9 29.0 24.1 14.6 17.7 19.3 30.7 11.3 31.0 24.7 24.1 18.2 33.1 26.2 13.0 13.4 8.6 12.7 8.6 15.0 21.0 19.8 17.4 21.0 30.9 14.3 13.8 13.8 28.9 17.8 22.6 13.9 9.3 26.6 35.8 10.9 31.8 16.3 15.3 12.2 12.1 17.3 18.7 11.6 15.1 24.5 9.9 17.8 15.2 18.0 44.4 21.7 26.5 17.3 18.1 37.5 27.1 10.5 19.7 23.2 11.9 41.7 27.6 17.3 25.6 10.6 22.3 12.4 14.6 31.8 14.7 18.4 27.0 10.4 28.4 24.2 11.3 25.7 8.8 20.7 31.0 18.0 19.3 18.9 21.8 30.7 17.8 14.2 17.2 1.4 24.7 21.9 28.3 24.1 18.2 18.6 21.2 10.2 22.7 18.1 13.5 20.5 24.1 16.2 19.5 JOSD1 KIAA0063 ENSG00000100221 "Josephin domain containing 1" Q15040 22 38685543-38701556 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001168 Uncertain "HPA001168: AB_1079162" "unprognostic (6.50e-2)" "unprognostic (1.06e-2)" "unprognostic (3.42e-3)" "unprognostic (5.67e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (4.50e-4)" "unprognostic (1.65e-2)" "unprognostic (5.10e-2)" "unprognostic (1.39e-1)" "unprognostic (3.23e-3)" "unprognostic (2.46e-1)" "unprognostic (1.83e-3)" "unprognostic (1.06e-1)" "unprognostic (4.41e-1)" "unprognostic (2.88e-2)" "unprognostic (4.41e-1)" 20.4 16.8 17.5 19.9 18.3 55.8 26.0 23.2 30.5 19.0 34.6 11.0 16.2 19.9 19.1 20.1 20.8 18.6 29.9 20.8 16.9 14.2 13.1 16.0 22.6 18.8 14.2 20.7 35.5 18.8 14.7 19.5 16.5 13.9 16.2 28.8 12.5 15.0 27.7 16.5 17.2 45.2 20.8 15.0 16.5 16.8 13.7 8.1 16.4 16.1 20.9 17.2 23.6 18.6 3.3 2.5 7.2 5.6 4.1 7.6 2.5 25.9 9.3 13.7 17.7 17.6 21.6 10.4 20.0 23.9 26.1 27.4 15.4 13.2 24.9 10.4 20.0 16.8 18.9 17.7 21.1 26.6 12.6 13.2 22.4 13.1 30.0 23.6 13.0 18.7 26.5 24.6 42.3 30.8 11.8 26.5 19.1 11.0 10.2 9.7 5.2 10.6 18.5 20.1 10.4 14.1 13.4 12.7 6.8 23.0 11.4 20.5 11.4 6.9 26.7 15.6 19.1 20.1 12.1 29.4 25.4 20.3 20.7 12.7 14.4 1.8 3.5 3.7 5.3 5.6 3.8 3.3 4.5 6.9 2.5 3.2 4.9 7.6 7.2 4.1 3.0 2.1 5.8 2.5 17.5 18.3 23.2 30.5 16.9 14.2 14.2 20.7 13.9 8.1 JOSD2 SBBI54 ENSG00000161677 "Josephin domain containing 2" Q8TAC2 19 50505998-50511353 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (8.77e-2)" "unprognostic (3.09e-2)" "unprognostic (2.59e-1)" "unprognostic (1.57e-2)" "unprognostic (7.25e-2)" "unprognostic (2.38e-1)" "prognostic unfavourable (6.04e-5)" "unprognostic (3.63e-2)" "unprognostic (2.41e-1)" "unprognostic (5.68e-2)" "unprognostic (1.75e-2)" "unprognostic (6.49e-2)" "unprognostic (2.42e-3)" "unprognostic (8.05e-2)" "unprognostic (2.04e-1)" "unprognostic (6.05e-2)" "unprognostic (9.34e-2)" 20.7 14.1 18.0 14.6 19.6 16.8 21.7 7.5 18.6 11.2 16.0 18.9 11.5 24.0 13.0 12.3 15.4 11.0 15.5 19.1 19.3 14.4 12.4 25.4 13.1 21.6 22.6 11.6 11.0 13.6 8.8 9.8 12.5 19.5 10.4 5.1 7.5 21.6 15.0 28.3 21.0 20.8 8.9 30.4 14.7 24.8 8.8 16.7 9.8 23.7 15.5 6.7 11.6 16.4 8.7 26.2 33.6 36.9 10.5 18.7 16.5 15.4 27.7 0.1 8.2 9.3 11.0 5.0 18.9 7.3 5.5 5.8 4.6 12.1 4.6 11.5 7.3 10.6 0.8 8.9 1.5 20.9 11.1 4.6 5.2 2.3 11.8 1.2 16.6 11.9 7.9 3.6 2.7 5.1 5.7 12.1 5.7 11.8 5.3 6.0 1.9 26.8 1.5 12.6 8.8 5.3 14.9 4.7 12.0 5.5 14.4 15.6 11.3 8.2 10.8 9.4 11.2 11.9 10.8 12.7 10.1 1.5 26.6 5.9 18.0 16.5 36.9 33.6 17.5 33.8 14.7 8.7 16.8 17.8 26.2 8.6 12.3 13.5 6.2 10.5 23.7 18.9 18.7 16.5 18.0 19.6 7.5 18.6 19.3 14.4 22.6 11.6 19.5 16.7 KATNA1 ENSG00000186625 "Katanin catalytic subunit A1" O75449 6 149594873-149648972 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036207 Approved Supported "Nucleoplasm,Centriolar satellite" "Centriolar satellite" Nucleoplasm "HPA036207: AB_10672238" "unprognostic (1.57e-1)" "unprognostic (2.41e-2)" "unprognostic (2.95e-2)" "unprognostic (3.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "prognostic unfavourable (3.57e-7)" "unprognostic (9.78e-2)" "unprognostic (8.89e-2)" "unprognostic (7.40e-2)" "unprognostic (2.70e-2)" "unprognostic (4.50e-2)" "unprognostic (3.92e-2)" "unprognostic (2.10e-1)" "unprognostic (3.37e-1)" "unprognostic (1.74e-3)" "unprognostic (8.85e-2)" 12.5 7.8 9.3 11.9 9.8 14.2 11.7 13.0 9.5 13.8 12.1 15.0 6.0 7.6 15.3 10.3 12.5 10.9 10.1 11.3 9.1 6.7 13.7 8.4 10.8 11.8 10.4 7.9 18.7 9.6 5.7 12.1 11.0 15.0 12.7 9.5 17.5 10.1 10.5 21.2 12.0 10.8 12.4 8.9 12.2 10.4 36.7 12.0 22.5 13.9 10.3 14.0 15.1 12.7 19.6 19.4 23.5 20.8 12.7 24.2 14.9 11.3 4.1 9.3 20.4 11.3 18.1 14.5 14.2 12.1 15.1 20.0 9.8 6.0 15.8 8.3 14.2 9.0 18.3 9.4 19.7 14.5 15.5 21.0 8.7 13.5 15.6 29.4 7.9 11.4 11.2 17.3 13.7 13.8 21.8 11.6 13.3 15.7 20.1 19.2 9.2 6.9 13.9 17.1 7.7 10.7 6.4 7.6 10.7 26.0 7.5 10.0 7.6 28.7 11.8 7.9 12.0 20.7 16.4 10.8 9.9 21.8 10.4 21.0 12.8 23.5 15.2 21.0 19.9 20.8 17.5 19.6 20.2 20.0 19.4 14.2 17.2 17.3 7.0 12.7 18.0 16.7 24.2 14.9 9.3 9.8 13.0 9.5 9.1 6.7 10.4 7.9 15.0 12.0 KATNAL1 MGC2599 ENSG00000102781 "Katanin catalytic subunit A1 like 1" Q9BW62 13 30202630-30307484 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046205 Uncertain Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA046205: AB_10965325" "unprognostic (3.34e-1)" "unprognostic (6.44e-3)" "unprognostic (2.08e-2)" "unprognostic (6.91e-2)" "unprognostic (2.53e-1)" "unprognostic (1.52e-1)" "unprognostic (1.57e-2)" "unprognostic (2.84e-2)" "unprognostic (3.43e-1)" "unprognostic (4.68e-3)" "unprognostic (4.54e-2)" "unprognostic (2.17e-2)" "unprognostic (1.84e-3)" "unprognostic (7.41e-2)" "unprognostic (6.42e-2)" "unprognostic (5.12e-2)" "unprognostic (1.83e-3)" 11.0 5.7 12.2 6.4 12.5 7.6 12.0 11.0 14.4 14.1 11.4 10.4 4.6 2.2 12.7 4.2 8.1 6.6 5.4 22.6 8.5 9.8 5.9 5.4 6.7 8.2 10.3 14.9 6.3 2.9 3.2 11.9 4.2 11.9 6.7 5.9 4.1 3.5 8.5 7.1 3.8 4.2 19.7 10.8 4.5 4.7 25.1 7.8 12.0 4.4 3.3 9.1 7.7 7.9 5.2 6.9 3.4 1.0 9.5 7.1 1.4 5.4 4.6 8.1 4.3 6.1 13.1 0.2 22.8 7.3 12.2 9.6 0.9 5.6 8.9 2.7 30.4 1.5 5.7 5.9 18.6 7.6 2.1 6.3 5.7 2.0 3.2 3.1 4.3 5.0 2.9 13.7 3.4 12.8 3.3 3.9 14.9 1.1 7.0 2.9 3.5 2.9 7.9 9.5 0.9 4.4 0.4 3.3 7.0 6.0 1.2 4.3 2.0 1.9 11.6 10.8 16.4 5.9 9.1 2.1 3.7 12.2 4.3 3.1 15.5 1.9 0.9 3.4 5.8 0.5 2.9 2.6 4.6 5.8 2.3 5.2 1.1 2.6 0.3 9.5 1.0 6.9 7.1 1.4 12.2 12.5 11.0 14.4 8.5 9.8 10.3 14.9 11.9 7.8 KATNAL2 "DKFZP667C165, MGC33211" ENSG00000167216 "Katanin catalytic subunit A1 like 2" Q8IYT4 18 46917492-47102243 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 30.3;testis: 33.2" "Cell line enhanced" "Detected in many" "AN3-CA: 14.8;Daudi: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040712, HPA042029" Approved Approved "Nucleoplasm,Intermediate filaments" "Nucleoplasm, Intermediate filaments" "HPA040712: , HPA042029: " "unprognostic (3.40e-1)" "unprognostic (7.75e-2)" "unprognostic (9.00e-3)" "unprognostic (9.28e-2)" "unprognostic (1.74e-2)" "unprognostic (6.55e-3)" "unprognostic (6.97e-2)" "unprognostic (1.28e-2)" "unprognostic (3.90e-2)" "unprognostic (5.36e-2)" "unprognostic (9.52e-6)" "unprognostic (1.28e-1)" "prognostic favourable (1.24e-7)" "unprognostic (1.64e-1)" "unprognostic (7.14e-4)" "unprognostic (1.06e-3)" "unprognostic (1.61e-1)" 5.5 2.9 8.2 4.1 9.7 2.8 7.1 4.0 7.5 2.5 2.4 11.3 2.5 1.8 2.8 7.1 2.7 8.6 5.1 4.3 8.1 7.6 9.5 5.2 4.6 3.4 9.6 6.2 3.1 3.3 30.3 7.0 2.2 9.0 3.4 3.1 6.4 3.4 3.7 6.0 8.0 1.5 2.3 8.7 3.3 2.0 33.2 6.3 2.4 15.5 1.1 3.0 2.3 2.5 3.1 0.6 2.7 1.3 0.8 1.5 0.3 1.9 4.3 2.3 14.8 4.8 5.9 1.1 1.8 1.6 1.5 1.9 0.2 5.0 19.6 1.5 2.8 0.6 4.7 0.5 1.1 2.0 2.5 0.8 1.3 0.3 2.0 1.2 1.9 12.1 1.8 2.5 0.6 0.5 0.7 1.5 8.4 1.9 1.1 2.6 5.3 2.6 5.4 1.1 0.0 4.7 0.4 5.4 5.9 1.9 0.4 0.6 11.2 10.9 1.0 5.0 0.5 1.9 1.2 1.3 1.0 13.2 2.7 12.4 9.5 1.7 0.7 0.5 1.1 1.3 0.9 2.2 0.9 0.5 0.3 3.1 1.5 1.4 2.7 0.8 0.9 0.6 0.2 0.3 8.2 9.7 4.0 7.5 8.1 7.6 9.6 6.2 9.0 6.3 KIAA0391 "MRPP3, PRORP" ENSG00000100890 KIAA0391 O15091 14 35121846-35277614 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA020459 Approved Supported Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA020459: " "unprognostic (6.44e-3)" "unprognostic (8.10e-2)" "unprognostic (7.71e-3)" "unprognostic (4.90e-2)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" "unprognostic (8.67e-2)" "unprognostic (1.94e-2)" "unprognostic (3.25e-4)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (9.67e-5)" "unprognostic (2.56e-1)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (6.65e-2)" 13.9 26.1 18.8 17.6 20.1 12.5 17.5 23.1 21.9 17.4 22.4 20.6 15.6 16.6 13.0 19.4 26.1 14.7 13.2 16.7 17.6 16.3 31.1 29.5 20.9 29.5 20.2 17.7 10.8 16.5 29.8 27.4 13.4 19.2 14.1 24.9 15.8 18.0 21.8 22.2 23.0 16.5 15.0 23.0 18.7 15.8 17.1 20.9 31.2 18.9 21.3 24.8 18.2 16.0 10.0 9.7 10.9 5.4 12.1 25.5 12.4 22.7 18.1 12.6 16.7 13.9 16.4 11.1 15.3 13.8 19.6 17.0 17.2 14.1 25.0 19.9 14.5 17.6 23.2 26.5 22.1 19.6 7.2 11.2 14.0 36.7 14.3 13.8 12.3 17.5 20.4 18.5 17.1 28.4 18.1 7.3 23.9 25.7 20.9 15.2 13.5 18.0 20.0 21.0 14.5 27.5 23.3 11.8 13.3 19.8 22.0 12.7 32.0 11.4 21.5 15.1 13.6 11.7 13.1 7.9 18.5 26.2 7.7 15.0 15.8 10.9 5.4 3.4 15.4 5.2 22.4 10.0 23.8 16.6 7.2 7.0 21.2 15.6 6.3 12.1 4.3 9.7 25.5 12.4 18.8 20.1 23.1 21.9 17.6 16.3 20.2 17.7 19.2 20.9 KL ENSG00000133116 Klotho Q9UEF7 13 33016433-33066145 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 64.3;parathyroid gland: 76.9;placenta: 25.5" "Group enriched" "Detected in some" 5 "HMC-1: 5.0;SK-BR-3: 9.4" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Region enhanced" "Detected in some" "pons and medulla: 11.6" "Cell type enhanced" "Detected in single" "classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Secreted to blood" 510400 "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favourable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favourable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 4.8 0.6 0.8 0.9 4.3 0.1 7.4 0.0 0.8 0.7 2.1 3.3 0.2 1.0 1.0 3.2 0.8 0.7 0.9 0.9 2.4 0.8 64.3 0.2 10.4 0.9 0.5 0.3 0.4 1.6 76.9 0.3 25.5 11.6 3.3 0.4 0.3 0.7 1.0 0.9 0.4 3.2 0.7 0.4 3.1 1.9 0.6 0.3 0.0 1.4 1.3 0.3 1.5 1.1 0.0 0.0 0.0 1.0 0.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.8 4.3 0.0 0.8 2.4 0.8 0.5 0.3 11.6 0.3 KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819148-50823787 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "pancreas: 742.6;salivary gland: 473.0" "Cell line enriched" "Detected in some" 23 "RPMI-8226: 28.8" "Group enriched" "Detected in many" 6 "colorectal cancer: 20.0;pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 10.9;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 14 "B-cells: 10.9" "Secreted to digestive system" 4300000 "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.2 2.5 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 3.8 0.1 0.1 0.1 0.1 0.1 0.1 742.6 0.0 0.1 0.1 0.1 0.2 1.9 0.1 473.0 0.1 0.1 1.8 0.6 0.1 0.1 0.3 0.1 0.1 0.1 0.1 1.2 0.2 0.2 0.1 0.1 10.9 0.7 0.1 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.2 0.2 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 10.9 0.0 0.0 0.2 3.8 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "prostate: 163.5" "Cell line enhanced" "Detected in many" "NB-4: 9.9" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA000764 Supported "Secreted in male reproductive system" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.0 0.1 0.0 0.1 0.0 1.1 0.2 0.0 0.6 0.0 0.0 0.0 0.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.5 0.0 0.1 2.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.2 0.0 2.2 1.9 5.7 2.2 1.6 1.3 0.5 1.7 1.1 0.6 1.6 0.0 0.8 4.9 0.5 0.3 0.2 0.2 0.6 0.7 1.8 0.2 0.0 2.0 0.2 0.0 0.3 1.7 1.1 0.0 1.3 0.4 0.0 0.3 3.1 0.4 0.3 0.3 0.4 0.0 1.4 1.9 0.3 1.8 1.2 9.9 1.1 0.0 0.9 0.0 2.8 0.0 1.6 0.9 1.5 0.3 1.3 1.3 1.2 0.4 0.8 1.3 1.9 4.8 1.6 1.8 3.2 0.8 1.9 1.7 1.4 0.9 2.2 1.6 1.2 1.0 1.0 1.0 0.8 1.0 0.5 2.2 0.8 1.3 5.7 1.6 0.8 1.9 0.4 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 KLK3 "APS, PSA" ENSG00000142515 "Kallikrein related peptidase 3" P07288 19 50854915-50860764 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 115 "prostate: 447.4" "Group enriched" "Detected in some" 135 "BEWO: 21.9;NB-4: 18.5;RPMI-8226: 12.2;SH-SY5Y: 7.3;U-2197: 7.5" "Cancer enriched" "Detected in some" 3905 "prostate cancer: 4241.6" "Region enriched" "Detected in single" 8 "cerebral cortex: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000070, HPA000764" Enhanced "Secreted in male reproductive system" "CAB000070: , HPA000764: AB_1079700" "unprognostic (5.06e-3)" "unprognostic (5.60e-2)" "unprognostic (9.93e-2)" "unprognostic (3.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.13e-3)" "unprognostic (1.94e-1)" "unprognostic (4.64e-1)" "unprognostic (3.15e-1)" 0.1 0.3 0.0 0.1 0.0 0.0 0.7 0.0 1.0 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 447.4 0.0 0.1 3.8 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.5 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976482-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 29.1;skin 1: 77.5;tongue: 90.2" "Group enriched" "Detected in some" 6 "CAPAN-2: 6.6;HaCaT: 25.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" 960000 "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavourable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 2.1 0.3 5.4 0.3 4.3 0.4 5.6 0.5 11.3 5.4 0.3 0.0 0.0 0.5 0.7 0.3 29.1 7.8 3.3 0.2 4.8 0.5 2.6 0.2 1.6 0.3 0.3 3.5 1.0 0.2 0.2 0.1 0.5 4.2 0.3 0.2 0.0 7.4 0.3 0.6 77.5 0.3 0.4 0.3 0.5 0.4 0.3 0.0 0.0 0.4 90.2 15.3 0.2 9.0 1.1 0.4 1.3 0.8 2.1 1.0 0.6 2.6 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.5 6.6 0.0 1.0 0.0 25.9 0.0 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 1.3 0.8 0.4 0.4 0.4 0.7 0.6 0.6 0.4 0.4 1.1 1.0 0.9 0.9 2.1 0.4 0.4 0.7 0.6 5.4 4.3 0.5 11.3 4.8 0.5 0.3 3.5 4.2 0.0 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 43.6;skin 1: 40.4;tongue: 46.9" "Group enriched" "Detected in some" 7 "A-431: 31.5;CAPAN-2: 41.3;HaCaT: 30.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "hippocampal formation: 39.6" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" 950000 Vesicles "CAB019393: , HPA035761: " "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavourable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavourable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavourable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavourable (6.17e-4)" 1.6 0.0 0.1 0.4 0.1 0.0 4.5 1.0 0.3 8.1 0.7 0.1 0.1 0.0 1.1 0.7 43.6 6.7 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 1.1 0.1 0.0 0.1 0.4 0.6 0.3 0.0 0.3 6.0 0.1 0.3 40.4 0.1 0.1 0.6 0.3 0.0 0.7 0.1 0.5 0.3 46.9 11.1 0.3 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 0.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.6 41.3 0.0 0.8 0.0 30.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.3 0.1 0.0 0.1 0.1 0.6 0.1 KLKB1 KLK3 ENSG00000164344 "Kallikrein B1" P03952 4 186208979-186258471 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Inflammatory response" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "liver: 102.9" "Cell line enhanced" "Detected in some" "NTERA-2: 7.1;SCLC-21H: 4.9;SK-MEL-30: 2.1;U-937: 2.4" "Cancer enriched" "Detected in some" 17 "liver cancer: 27.6" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 7 "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 8 "T-cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" 28860000000 4900000000 "unprognostic (4.80e-2)" "unprognostic (4.53e-3)" "unprognostic (4.36e-2)" "unprognostic (4.17e-2)" "unprognostic (5.93e-2)" "unprognostic (1.90e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-1)" "unprognostic (8.14e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-2)" "unprognostic (6.01e-2)" "unprognostic (7.30e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" 0.3 0.3 0.8 0.3 1.2 0.0 0.3 0.7 0.5 0.3 0.4 0.3 0.3 0.7 0.4 0.4 0.3 0.2 0.7 0.5 0.6 0.5 1.3 102.9 0.3 0.3 0.5 0.5 0.3 1.3 0.5 1.0 0.4 0.4 0.3 0.3 0.5 0.3 0.3 0.5 0.1 0.6 0.3 0.3 0.5 0.0 0.3 0.3 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 7.1 0.0 0.1 0.0 0.2 1.3 0.0 4.9 0.4 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.2 0.7 0.5 0.6 0.5 0.5 0.5 0.4 0.3 KYNU ENSG00000115919 Kynureninase Q16719 2 142877498-143055832 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 35.9;liver: 41.1;placenta: 34.3" "Cell line enhanced" "Detected in some" "A549: 40.1;HeLa: 44.8;Hep G2: 27.2;hTEC/SVTERT24-B: 23.5;SiHa: 22.2;U-87 MG: 70.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 18 "classical monocyte: 28.7;intermediate monocyte: 35.9;memory B-cell: 19.7;myeloid DC: 28.4;naive B-cell: 12.7;non-classical monocyte: 29.2;plasmacytoid DC: 19.9" "Group enriched" "Detected in many" 21 "B-cells: 19.7;dendritic cells: 28.4;monocytes: 35.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA031686 Enhanced Supported Nucleoplasm,Cytosol 360000 Cytosol Nucleoplasm "HPA031686: " "unprognostic (2.58e-2)" "unprognostic (3.39e-3)" "unprognostic (1.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.36e-3)" "unprognostic (3.58e-3)" "unprognostic (4.88e-2)" "unprognostic (3.35e-2)" "unprognostic (2.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-3)" "unprognostic (3.65e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-1)" 9.0 3.7 2.2 11.0 3.7 3.9 15.4 0.6 1.7 3.0 1.2 1.3 0.8 0.2 1.1 2.6 5.6 1.5 4.4 3.8 1.4 1.1 8.4 41.1 12.7 13.7 2.9 0.4 1.7 1.0 0.2 1.6 34.3 2.7 1.9 1.2 1.5 3.0 0.8 0.7 1.5 2.7 2.0 6.3 16.0 2.4 7.0 2.6 2.7 2.2 1.7 13.0 12.4 2.6 19.7 28.4 1.3 35.9 0.4 0.1 11.1 0.0 40.1 0.1 0.1 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.7 0.5 2.4 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 44.8 27.2 0.5 0.1 0.2 3.9 3.2 23.5 0.1 0.0 0.1 0.2 0.3 20.5 0.0 2.4 0.1 0.1 0.0 0.2 0.1 0.6 20.7 0.1 0.0 22.2 3.3 0.2 11.1 5.7 0.3 1.3 0.1 19.6 0.0 0.1 0.0 0.0 70.2 4.6 0.1 0.1 28.7 0.5 0.1 35.9 0.1 19.7 0.1 0.1 28.4 12.7 0.1 0.0 1.3 0.4 29.2 19.9 0.1 11.1 2.2 3.7 0.6 1.7 1.4 1.1 2.9 0.4 2.7 2.6 LAP3 "LAP, LAPEP, PEPS" ENSG00000002549 "Leucine aminopeptidase 3" P28838 4 17577192-17607972 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029606, HPA029607" Enhanced Supported Nucleoplasm,Midbody,Cytosol 4100000 Cytosol "Nucleoplasm, Midbody" "HPA029606: AB_10599288, HPA029607: AB_10611381" "unprognostic (2.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (2.87e-1)" "unprognostic (2.16e-1)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.44e-3)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (4.29e-3)" "unprognostic (1.73e-1)" "unprognostic (3.28e-2)" "unprognostic (3.06e-1)" "unprognostic (8.79e-2)" 42.5 29.7 23.2 43.9 38.5 18.1 30.7 8.5 23.5 13.3 21.0 23.5 12.3 27.5 17.2 20.8 19.3 18.7 24.3 25.4 24.4 17.0 71.7 70.3 39.4 54.2 33.7 16.1 13.5 14.7 23.5 13.2 25.0 34.9 15.3 22.7 15.0 23.0 12.1 33.3 20.9 30.6 26.9 35.0 54.9 20.8 19.3 30.7 19.9 29.4 21.7 32.1 24.4 23.7 7.5 45.7 9.5 46.1 11.8 12.9 25.3 10.8 9.5 9.1 8.6 18.1 22.1 0.1 17.1 19.3 62.3 75.7 17.3 20.7 42.7 11.4 13.1 6.7 34.2 12.1 23.7 16.3 9.8 23.7 10.5 22.6 21.1 21.3 15.2 22.4 7.7 20.4 10.7 21.6 22.9 30.5 14.6 11.7 18.9 29.2 19.0 18.2 29.4 8.7 21.6 16.2 12.7 13.5 11.1 15.7 9.7 33.5 8.2 8.2 14.0 15.8 10.7 16.6 29.7 28.1 42.9 36.9 21.4 35.5 15.3 8.4 43.4 9.5 8.0 46.1 7.4 7.5 7.5 8.5 45.7 5.2 6.5 6.8 6.2 11.8 31.9 25.9 12.9 25.3 23.2 38.5 8.5 23.5 24.4 17.0 33.7 16.1 34.9 30.7 LCT ENSG00000115850 Lactase P09848 2 135787840-135837180 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 133 "intestine: 255.5" "Group enriched" "Detected in some" 5 "MOLT-4: 6.8;RPMI-8226: 13.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Region enriched" "Detected in single" 16 "hippocampal formation: 17.3" "unprognostic (2.21e-2)" "unprognostic (1.65e-4)" "unprognostic (2.54e-1)" "unprognostic (2.06e-1)" "unprognostic (3.39e-2)" "unprognostic (8.03e-4)" "unprognostic (3.55e-3)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (3.57e-1)" "unprognostic (1.69e-1)" "unprognostic (9.32e-2)" "unprognostic (1.64e-4)" "unprognostic (4.90e-2)" "unprognostic (8.92e-2)" "unprognostic (8.97e-2)" "unprognostic (1.02e-1)" 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 209.8 0.0 0.0 67.7 0.1 0.0 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 255.5 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 6.8 1.1 0.0 0.0 1.6 0.0 13.6 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.1 0.2 0.1 0.3 0.2 0.1 0.0 0.0 0.0 LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748702 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "RPMI-8226: 127.6;U-266/70: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 11 "plasmacytoid DC: 54.2" "Lineage enriched" "Detected in many" 11 "dendritic cells: 54.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" 1200000 Vesicles Nucleoplasm "HPA001426: AB_1079247" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.47e-1)" "prognostic favourable (4.70e-4)" "unprognostic (8.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.18e-3)" "unprognostic (7.24e-2)" 42.9 16.3 8.6 17.4 10.7 3.5 19.9 5.8 17.9 13.3 22.3 11.7 13.9 24.2 12.1 48.1 17.4 14.1 32.7 38.8 10.3 10.1 87.6 44.6 31.5 42.4 8.3 10.1 20.5 14.6 54.4 9.7 113.6 9.9 22.0 24.5 23.2 22.6 8.4 17.3 11.9 37.1 23.3 11.5 58.3 23.7 14.0 7.9 17.2 36.8 19.2 17.3 31.4 18.2 4.7 54.2 0.7 0.8 1.0 4.3 1.7 4.8 7.0 4.7 8.6 14.6 11.8 16.4 10.5 10.0 10.9 12.9 5.4 8.7 2.7 15.5 17.1 12.1 0.0 9.0 5.2 0.2 5.4 0.1 3.9 6.2 4.3 0.1 0.4 8.3 4.4 10.5 6.0 12.9 1.0 22.6 0.7 6.5 1.2 0.2 2.3 4.8 1.2 4.1 127.6 11.8 19.0 5.1 3.5 14.5 8.9 7.5 6.6 0.0 7.0 5.4 6.9 9.7 3.1 70.2 8.2 3.6 3.0 0.1 10.3 0.7 0.4 0.1 0.2 0.8 0.4 4.7 1.4 0.4 5.0 3.4 4.3 2.5 0.5 1.0 0.2 54.2 2.6 1.7 8.6 10.7 5.8 17.9 10.3 10.1 8.3 10.1 9.9 7.9 LHPP HDHD2B ENSG00000107902 "Phospholysine phosphohistidine inorganic pyrophosphate phosphatase" Q9H008 10 124461834-124617888 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 106.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009163, HPA009269" Enhanced Supported "Nuclear speckles,Cytosol" 880000 "Nuclear speckles, Cytosol" "HPA009163: AB_1079250, HPA009269: AB_1079249" "unprognostic (3.46e-2)" "unprognostic (1.23e-2)" "unprognostic (4.78e-2)" "unprognostic (3.89e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-1)" "unprognostic (5.77e-3)" "unprognostic (2.02e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (6.42e-2)" "unprognostic (5.55e-2)" "unprognostic (1.79e-3)" "unprognostic (2.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" 9.6 14.2 37.3 6.0 34.0 6.9 7.9 11.9 34.2 12.3 13.6 29.7 8.2 17.9 7.5 11.0 12.7 8.1 8.3 9.8 43.0 31.5 18.6 33.8 6.6 8.2 62.7 19.3 5.5 12.2 6.6 5.6 7.2 20.5 6.9 6.7 6.7 13.3 10.6 6.5 8.9 15.7 8.1 106.0 8.2 12.4 14.2 19.5 7.1 20.5 3.6 11.2 8.7 5.7 24.7 20.0 13.3 16.1 3.9 17.2 12.9 14.7 7.3 3.0 7.5 11.6 9.5 7.9 5.4 11.1 3.4 6.3 1.3 13.7 14.6 12.6 8.1 16.0 0.9 2.8 3.6 3.2 10.5 10.6 2.3 6.7 11.8 2.1 17.3 7.0 12.5 3.4 8.2 5.4 5.2 5.8 4.2 14.6 7.0 6.8 5.3 4.1 7.5 3.3 18.6 7.4 1.9 1.6 9.0 3.8 13.9 4.9 10.5 0.3 2.5 5.3 7.9 4.4 1.4 4.9 1.5 4.7 4.9 4.1 1.2 4.6 16.1 13.3 9.5 13.5 12.4 23.7 11.1 10.1 20.0 24.7 13.7 9.6 2.7 3.9 14.9 7.5 17.2 12.9 37.3 34.0 11.9 25.0 43.0 31.5 62.7 19.3 20.5 19.5 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 139.0" "Cell line enhanced" "Detected in many" "AN3-CA: 60.3;ASC TERT1: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 31.8;intermediate monocyte: 68.4;myeloid DC: 23.3;non-classical monocyte: 35.6" "Group enriched" "Detected in all" 5 "dendritic cells: 23.3;monocytes: 68.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported Vesicles "Intracellular and membrane" 150000 Vesicles "CAB034892: AB_784329, HPA057052: " "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 139.0 16.3 15.8 14.4 22.7 7.8 19.9 8.8 21.4 13.4 28.1 61.3 3.4 37.4 10.2 5.2 9.5 9.0 19.4 8.7 22.5 13.8 10.8 49.3 38.5 45.7 41.6 13.4 10.4 9.5 17.5 6.3 17.8 28.4 7.4 16.7 5.7 11.0 8.8 4.1 6.8 65.8 11.3 55.1 87.3 7.9 3.1 37.2 7.0 8.3 4.7 10.0 15.1 8.6 7.0 23.3 3.2 68.4 5.5 8.3 25.5 53.8 8.3 5.5 60.3 56.9 75.6 1.6 28.6 33.5 11.9 21.5 3.2 29.1 9.9 5.6 44.8 54.1 2.4 15.5 8.9 14.0 5.6 4.1 3.5 12.8 15.0 8.0 8.2 33.6 11.1 12.7 6.9 2.3 0.0 18.6 9.3 4.5 6.9 5.4 3.6 9.4 4.5 6.5 9.2 11.0 8.5 1.8 3.8 6.9 9.0 21.0 10.3 10.3 4.3 10.2 2.7 21.8 6.9 9.7 10.2 4.1 12.2 17.6 12.7 0.8 31.8 3.2 8.2 68.4 8.2 6.5 7.3 7.8 23.3 7.0 7.7 8.3 1.4 5.5 35.6 4.7 7.1 25.5 15.8 22.7 8.8 21.4 22.5 13.8 41.6 13.4 28.4 37.2 LIPC "HL, HTGL" ENSG00000166035 "Lipase C, hepatic type" P11150 15 58410569-58569843 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 91.7" "Cell line enhanced" "Detected in some" "CACO-2: 6.8;EFO-21: 5.2;Hep G2: 19.5;HMC-1: 5.7;MOLT-4: 4.4;U-2197: 15.4" "Group enriched" "Detected in some" 14 "liver cancer: 20.4;renal cancer: 10.4" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 8 "granulocytes: 3.7;NK-cells: 3.0;T-cells: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" 3200000 "unprognostic (1.76e-2)" "unprognostic (9.15e-3)" "unprognostic (7.89e-2)" "unprognostic (7.15e-4)" "unprognostic (1.40e-1)" "unprognostic (1.33e-2)" "unprognostic (9.93e-3)" "unprognostic (6.25e-2)" "unprognostic (3.79e-2)" "unprognostic (1.10e-2)" "unprognostic (3.06e-1)" "unprognostic (2.31e-1)" "unprognostic (2.82e-2)" "unprognostic (1.41e-1)" "unprognostic (2.87e-2)" "unprognostic (1.80e-2)" "unprognostic (2.27e-2)" 0.2 0.1 0.4 1.1 0.7 0.0 0.7 0.1 0.4 0.3 0.2 0.6 0.0 0.7 0.1 0.4 0.2 0.4 0.3 0.3 0.4 0.2 3.0 91.7 0.3 0.2 1.2 0.2 0.3 1.0 0.0 1.0 0.1 1.5 0.3 0.3 0.5 0.1 1.5 0.1 0.3 0.3 0.1 1.2 0.4 0.2 0.1 0.5 2.7 0.5 0.0 0.1 1.1 0.2 0.1 0.2 3.7 0.4 3.0 4.5 2.5 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.7 0.0 0.0 6.8 0.0 0.0 5.2 0.2 0.0 0.0 0.0 0.0 0.4 0.0 2.4 0.0 19.5 0.4 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 4.4 0.6 0.0 0.0 0.9 0.3 0.0 2.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 15.4 0.0 0.0 0.0 0.1 0.1 0.4 0.0 3.7 0.3 0.0 3.0 0.2 4.5 0.0 0.8 2.2 0.2 0.1 1.0 3.2 0.4 3.0 0.4 0.1 2.1 2.5 0.4 0.7 0.1 0.4 0.4 0.2 1.2 0.2 1.5 0.5 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401507-42427426 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 207.4;breast: 65.1" "Cell line enriched" "Detected in many" 7 "ASC diff: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol Cytosol "CAB017700: AB_2135504, HPA006567: " "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favourable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 207.4 6.0 3.2 2.9 9.4 2.1 65.1 2.0 6.8 1.2 6.7 19.6 0.8 2.4 1.7 1.3 2.2 1.6 3.6 4.8 6.2 4.2 1.5 1.1 1.4 2.7 18.0 2.3 1.5 2.2 2.2 0.8 1.7 9.9 1.7 1.3 3.7 5.4 1.7 3.7 2.9 3.4 1.7 19.2 3.1 1.6 9.0 10.8 1.7 1.5 1.8 1.9 2.0 3.7 6.1 4.8 10.8 12.1 4.1 5.2 4.0 4.8 3.7 2.4 0.9 56.0 0.5 0.0 2.3 1.2 3.7 3.4 0.9 1.8 8.0 2.5 0.7 2.1 1.4 4.5 0.4 1.5 2.4 2.2 1.8 0.1 1.1 0.0 5.5 0.4 4.3 0.6 0.8 1.0 1.0 5.1 0.4 0.0 5.6 0.2 0.3 1.1 4.6 0.4 2.6 1.0 5.1 3.4 3.5 2.0 2.3 2.1 0.6 2.9 1.8 1.0 3.2 0.4 2.0 3.8 3.1 5.9 2.5 0.2 3.4 10.8 12.1 4.7 3.6 6.0 3.3 4.8 4.6 5.2 4.8 6.1 4.1 3.7 2.0 4.1 3.3 3.9 3.9 4.0 3.2 9.4 2.0 6.8 6.2 4.2 18.0 2.3 9.9 10.8 LIPF "HGL, HLAL" ENSG00000182333 "Lipase F, gastric type" P07098 10 88664441-88678814 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "stomach 1: 762.9" "Cell line enhanced" "Detected in some" "HMC-1: 6.2;MOLT-4: 4.9;NTERA-2: 5.2;REH: 3.0;THP-1: 9.8;U-2 OS: 3.5;U-266/70: 4.8" "Cancer enriched" "Detected in some" 75 "stomach cancer: 278.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.9" "Cell type enriched" "Detected in single" 16 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.5" "Region enriched" "Detected in single" 51 "olfactory region: 9.9" HPA045930 Enhanced "Secreted to digestive system" "HPA045930: AB_10959518" "unprognostic (1.53e-1)" "unprognostic (1.83e-1)" 0.1 0.0 0.1 0.1 0.5 0.0 0.1 0.1 1.9 0.1 0.2 28.2 0.1 8.2 0.1 0.1 31.6 0.1 0.6 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.1 9.9 0.1 0.1 0.0 0.1 0.1 0.1 0.1 762.9 0.1 0.1 0.2 0.1 1.1 0.1 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.1 5.2 0.0 3.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 3.5 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 1.9 0.1 0.0 0.1 0.1 0.1 0.1 LIPG EDL ENSG00000101670 "Lipase G, endothelial type" Q9Y5X9 18 49560699-49599182 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 37.0;placenta: 44.7;thyroid gland: 84.3" "Cell line enhanced" "Detected in some" "AN3-CA: 30.7;HaCaT: 47.1;RPTEC TERT1: 31.3;TIME: 61.1" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 20.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 3.7;basal ganglia: 2.1;cerebral cortex: 2.9;hippocampal formation: 1.8;olfactory region: 1.9" "Low region specificity" "Detected in all" HPA016966 Uncertain "Secreted to blood" 656750000 170000 "HPA016966: AB_1852893" "unprognostic (2.20e-2)" "unprognostic (3.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.25e-3)" "unprognostic (6.38e-2)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" "unprognostic (4.55e-3)" "unprognostic (9.93e-2)" "unprognostic (1.44e-1)" "unprognostic (6.44e-2)" "unprognostic (8.74e-2)" "unprognostic (2.98e-1)" "unprognostic (8.68e-2)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (1.35e-1)" 1.5 0.4 0.8 4.7 0.7 0.1 0.8 2.0 0.7 0.4 5.6 3.9 15.0 1.9 0.4 3.1 1.0 0.5 4.3 1.2 1.1 0.9 5.2 37.0 4.4 0.7 1.1 0.1 0.5 1.0 0.0 0.6 44.7 1.4 1.0 2.2 8.3 0.6 24.6 2.6 1.1 7.6 2.2 1.4 0.4 1.4 5.8 0.4 0.3 84.3 2.1 0.5 2.0 0.6 1.2 0.6 2.1 0.6 1.7 0.8 0.1 0.5 0.0 13.5 30.7 0.1 0.0 0.2 0.1 1.4 0.0 0.0 13.3 4.8 0.0 7.5 0.0 47.1 2.0 9.6 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.2 1.4 10.8 4.8 9.4 7.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.7 31.3 3.6 0.2 0.0 0.2 0.3 0.0 0.0 0.0 61.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.6 0.4 0.7 0.4 0.4 0.8 0.5 0.5 0.2 1.2 0.8 0.7 2.1 1.7 0.4 0.6 0.4 0.1 0.8 0.7 2.0 0.5 1.1 0.9 1.1 0.1 1.4 0.4 LNPEP "CAP, IRAP, P-LAP, PLAP" ENSG00000113441 "Leucyl and cystinyl aminopeptidase" Q9UIQ6 5 96935394-97037515 "Enzymes, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "placenta: 104.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043642 Approved "Intracellular and membrane" 390000 "HPA043642: AB_10964137" "unprognostic (1.52e-1)" "unprognostic (5.39e-2)" "unprognostic (7.78e-2)" "unprognostic (1.53e-2)" "unprognostic (6.38e-2)" "unprognostic (6.59e-3)" "unprognostic (6.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.11e-1)" "unprognostic (3.54e-3)" "unprognostic (6.24e-2)" "unprognostic (2.08e-1)" "unprognostic (3.28e-1)" "unprognostic (4.13e-3)" "unprognostic (1.46e-1)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" 9.8 4.7 5.6 12.0 7.3 13.2 7.7 23.3 12.9 6.3 7.6 6.9 7.8 4.2 8.2 4.4 10.2 6.6 4.3 10.1 5.2 5.6 7.6 4.3 6.9 15.9 7.7 8.8 8.2 5.9 13.8 9.7 104.4 9.1 7.9 6.8 3.9 7.8 7.7 13.2 14.0 9.0 6.6 7.5 10.0 8.5 3.3 7.7 23.6 7.2 2.9 15.8 8.9 7.7 4.1 3.5 5.0 12.8 11.2 7.9 4.3 5.3 6.2 2.8 3.0 17.1 8.2 3.3 5.5 7.3 6.5 9.9 5.2 8.7 26.5 10.4 7.4 7.1 3.6 10.4 6.8 9.4 2.0 6.6 4.5 3.6 4.4 7.6 9.2 6.3 6.5 9.4 6.9 6.8 2.8 17.6 7.4 4.8 9.0 5.3 0.6 3.3 6.6 10.6 4.0 23.2 11.1 5.5 1.4 6.7 5.9 3.3 18.1 10.1 13.5 9.5 5.3 7.5 8.3 3.8 8.8 24.2 8.4 7.3 4.3 5.0 3.3 4.4 7.9 5.5 6.8 3.1 5.9 6.1 3.5 4.1 5.9 6.4 4.1 11.2 12.8 3.3 5.1 4.3 5.6 7.3 23.3 12.9 5.2 5.6 7.7 8.8 9.1 7.7 LONP1 "hLON, LonHS, PIM1, PRSS15" ENSG00000196365 "Lon peptidase 1, mitochondrial" P36776 19 5691834-5720572 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Hydrolase, Protease, Serine protease" "Cataract, Deafness, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 78.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002034, HPA002192" Supported Enhanced Nucleoplasm,Mitochondria Mitochondria Nucleoplasm "HPA002034: AB_2756304, HPA002192: AB_1079695" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (2.43e-1)" "unprognostic (2.43e-2)" "unprognostic (2.84e-1)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (5.56e-2)" "unprognostic (2.71e-1)" "unprognostic (7.57e-2)" "unprognostic (4.04e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" 15.8 78.3 16.4 12.8 19.8 12.5 13.9 16.1 22.8 11.3 13.6 15.8 13.3 13.7 10.5 13.8 12.7 12.7 15.7 27.3 15.4 15.3 19.9 49.6 10.3 14.5 17.7 14.9 15.5 17.7 17.6 16.8 16.6 16.2 11.7 8.5 12.7 18.5 14.7 38.0 14.7 13.9 11.5 12.7 15.5 13.5 9.8 13.3 13.8 21.2 15.3 11.8 14.7 12.5 6.7 6.5 6.0 6.2 4.0 7.2 3.0 23.0 23.9 7.9 25.3 9.4 6.7 24.7 14.7 11.7 15.9 19.5 20.4 8.3 29.0 20.6 15.4 9.8 20.4 17.8 7.7 17.1 16.8 16.0 20.9 26.7 43.7 36.4 16.8 12.6 25.6 15.1 29.9 12.7 42.3 57.8 7.3 15.3 18.0 21.7 28.3 31.6 19.0 11.4 31.2 8.8 13.7 21.1 21.1 12.9 18.9 51.6 11.1 45.7 9.0 8.1 8.9 22.5 21.4 60.9 37.5 25.7 36.5 39.9 14.6 6.0 4.1 0.8 6.4 6.2 4.1 6.0 5.6 6.1 4.3 6.7 7.2 4.8 0.5 4.0 2.4 6.5 4.0 3.0 16.4 19.8 16.1 22.8 15.4 15.3 17.7 14.9 16.2 13.3 LONP2 "LONP, LONPL, MGC4840" ENSG00000102910 "Lon peptidase 2, peroxisomal" Q86WA8 16 48244296-48363122 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008862 Uncertain "HPA008862: AB_2137156" "unprognostic (8.08e-3)" "prognostic unfavourable (4.55e-4)" "unprognostic (1.75e-2)" "unprognostic (2.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.60e-2)" "unprognostic (7.59e-3)" "unprognostic (2.13e-1)" "unprognostic (2.36e-1)" "unprognostic (3.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.40e-1)" "prognostic favourable (6.71e-7)" "unprognostic (6.53e-2)" "unprognostic (1.49e-1)" "unprognostic (5.60e-2)" "unprognostic (1.33e-1)" 15.8 17.0 16.0 13.9 22.2 9.4 36.1 18.9 20.7 16.1 17.4 16.3 15.3 15.2 15.8 20.6 14.5 17.6 19.0 16.7 15.0 15.0 15.9 69.2 11.3 12.8 15.2 15.8 22.1 20.7 40.0 23.3 11.1 17.2 23.1 14.8 30.9 15.0 18.1 18.0 13.5 14.8 16.3 14.1 12.5 14.9 7.0 13.7 14.9 24.9 11.6 13.2 16.7 13.7 13.3 13.1 8.7 13.7 9.0 15.9 11.0 13.7 19.3 9.7 14.9 25.7 21.2 18.4 17.8 13.6 16.7 7.7 10.0 7.1 6.3 17.6 17.8 17.3 19.7 19.6 23.4 10.2 12.4 9.2 12.3 21.8 15.8 15.4 12.4 19.7 21.9 15.6 14.7 12.4 15.5 6.8 17.2 12.4 14.9 7.7 8.1 19.2 19.4 19.8 19.9 18.9 9.3 17.0 10.1 20.1 22.6 17.9 9.5 11.8 16.5 17.3 10.3 15.0 13.6 13.8 12.5 10.4 20.2 10.4 12.5 6.8 13.7 8.7 13.3 13.6 14.0 12.8 15.9 13.5 13.1 13.3 15.0 13.8 5.3 9.0 13.6 9.6 11.8 11.0 16.0 22.2 18.9 20.7 15.0 15.0 15.2 15.8 17.2 13.7 LPIN1 KIAA0188 ENSG00000134324 "Lipin 1" Q14693 2 11677595-11827409 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024591, HPA038021" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA024591: , HPA038021: AB_10669514" "unprognostic (1.97e-1)" "unprognostic (2.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.87e-2)" "unprognostic (9.17e-2)" "unprognostic (2.69e-2)" "unprognostic (8.20e-2)" "unprognostic (5.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (2.45e-3)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.58e-3)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" "unprognostic (4.02e-1)" 18.1 10.1 13.0 10.7 18.3 6.0 22.1 20.0 16.4 10.5 8.6 10.9 7.3 8.9 11.0 15.0 20.0 7.0 10.4 12.8 11.6 11.9 7.6 13.2 8.0 15.4 13.2 11.2 19.3 7.5 17.2 32.0 9.0 17.9 9.6 7.1 9.0 14.4 11.6 88.4 6.5 9.2 11.0 10.3 8.4 7.6 39.0 13.2 8.3 8.1 14.0 19.2 10.4 21.7 6.5 9.6 11.6 2.8 8.0 11.1 3.2 5.4 6.5 5.4 12.1 25.1 27.9 2.8 7.6 13.2 5.0 8.6 2.3 5.4 2.7 1.0 6.5 5.9 6.1 16.8 4.6 11.2 3.4 6.7 3.6 3.5 8.8 4.6 31.6 25.1 7.5 20.5 7.8 9.5 9.2 24.3 3.6 2.1 4.3 4.0 5.6 6.6 6.0 10.0 17.0 12.5 3.5 15.1 11.9 2.7 6.6 17.3 1.6 2.6 6.7 7.9 7.1 5.0 6.6 38.2 29.5 5.1 11.1 8.3 5.8 9.5 2.8 11.6 10.3 2.1 11.1 6.5 9.6 9.7 2.5 5.0 8.4 7.1 1.1 8.0 2.1 9.6 10.5 3.2 13.0 18.3 20.0 14.4 11.6 11.9 13.2 11.2 17.9 13.2 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013315 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 83.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 6 "granulocytes: 20.8;NK-cells: 10.1;T-cells: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: " "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favourable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 6.8 5.6 13.0 10.5 18.4 9.2 7.7 11.9 16.5 6.6 25.2 10.4 2.4 31.6 6.7 3.9 5.9 6.3 14.3 5.1 11.0 14.5 20.7 83.9 11.8 11.8 11.2 9.8 8.8 9.0 9.7 8.2 16.3 15.3 5.8 7.4 6.8 4.4 5.3 2.2 2.7 43.3 6.1 9.6 10.7 15.6 13.5 9.6 6.3 7.5 1.5 10.0 6.8 6.7 1.2 1.1 20.8 2.0 10.1 9.5 2.1 4.9 6.7 10.6 3.7 18.4 17.1 6.3 11.9 14.6 11.9 11.6 8.7 4.2 3.6 7.3 18.3 0.2 8.7 3.7 9.4 7.0 1.8 9.2 5.2 9.9 17.2 7.3 10.1 17.2 2.5 11.8 10.3 14.8 8.3 1.9 16.6 3.7 9.1 6.3 3.4 9.6 16.0 9.2 13.4 9.5 11.1 8.9 6.2 11.2 5.3 3.8 0.0 10.0 20.8 15.4 18.7 19.7 8.8 3.5 5.3 7.8 13.6 7.5 5.4 6.5 2.0 6.1 9.3 1.3 9.5 0.9 7.1 5.3 0.8 1.2 7.3 4.7 20.8 10.1 0.6 1.1 6.3 2.1 13.0 18.4 11.9 16.5 11.0 14.5 11.2 9.8 15.3 9.6 LPIN3 "LIPN3L, SMP2" ENSG00000132793 "Lipin 3" Q9BQK8 20 41340920-41360582 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 49.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "NK-cell: 6.3" "Group enriched" "Detected in many" 4 "granulocytes: 1.8;NK-cells: 6.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA051466, HPA052667, HPA070640" Approved Supported Cytosol Cytosol "HPA051466: , HPA052667: , HPA070640: " "unprognostic (2.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.68e-1)" "prognostic unfavourable (9.74e-4)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (6.91e-3)" "unprognostic (4.26e-2)" "unprognostic (1.74e-1)" "prognostic unfavourable (1.74e-4)" "unprognostic (4.29e-2)" "unprognostic (7.79e-2)" "prognostic unfavourable (1.14e-5)" "unprognostic (5.60e-3)" "unprognostic (2.02e-1)" "unprognostic (1.35e-1)" "unprognostic (3.37e-3)" 11.6 3.7 3.0 8.1 5.2 0.1 23.4 1.5 3.0 10.9 29.2 2.8 13.5 26.8 12.8 21.6 16.3 7.5 11.2 8.8 3.6 0.7 28.2 14.4 4.5 1.6 2.8 3.7 7.9 7.4 8.1 6.7 4.4 4.2 10.1 8.8 8.7 11.0 15.1 1.8 26.1 49.1 5.5 2.4 2.7 7.4 2.5 1.5 1.2 14.2 10.6 9.0 8.0 12.5 0.9 0.7 1.8 0.9 6.3 0.8 0.2 6.8 6.7 0.4 4.0 11.0 17.1 5.2 4.2 5.9 5.1 7.0 12.5 6.1 0.3 5.3 9.3 17.4 2.0 11.0 3.2 0.1 3.9 0.3 9.4 6.3 1.8 0.0 4.7 12.3 14.0 8.7 3.4 1.3 1.7 0.2 6.4 14.6 0.0 0.1 0.6 6.9 0.0 0.1 0.4 18.1 8.6 0.5 0.1 5.6 7.2 3.6 8.5 3.4 0.4 0.3 1.7 5.8 0.0 3.4 1.8 0.0 0.1 0.1 0.3 1.8 0.5 0.7 0.5 0.5 0.8 0.6 0.7 0.4 0.3 0.9 0.7 0.6 1.8 6.3 0.9 0.7 0.5 0.2 3.0 5.2 1.5 3.0 3.6 0.7 2.8 3.7 4.2 1.5 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967258 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease mutation, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 178.6;breast: 146.2;heart muscle: 121.4" "Cell line enriched" "Detected in some" 5 "AF22: 89.3" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Region enhanced" "Detected in many" "basal ganglia: 16.3" "Cell type enhanced" "Detected in some" "non-classical monocyte: 7.1" "Lineage enriched" "Detected in many" 5 "monocytes: 7.1" "Region enhanced" "Detected in many" "basal ganglia: 40.6" "Region enriched" "Detected in all" 4 "basal ganglia: 64.0" HPA048749 Supported Vesicles "Secreted to blood" 880000 Vesicles "HPA048749: " "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavourable (6.07e-4)" 178.6 4.3 2.0 11.4 16.3 0.6 146.2 3.9 8.0 1.0 16.9 0.3 27.3 0.8 1.3 1.1 1.1 0.7 8.2 121.4 2.8 2.3 4.8 0.6 20.7 7.0 4.5 0.7 2.7 1.8 32.6 0.9 7.1 1.7 0.9 1.8 8.4 9.2 85.1 53.8 1.8 3.1 1.3 2.8 0.8 1.8 0.7 3.4 0.0 2.7 9.7 1.0 3.2 6.1 0.0 0.7 1.3 7.1 0.0 0.1 0.4 0.0 0.0 89.3 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 14.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 7.2 0.0 1.6 1.3 0.0 2.8 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.4 2.0 16.3 3.9 2.3 2.8 2.3 4.5 0.7 1.7 3.4 LTA4H ENSG00000111144 "Leukotriene A4 hydrolase" P09960 12 96000828-96043520 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008399, CAB015221, HPA017017" Supported Approved Nucleoplasm,Cytosol 85000000 "Nucleoplasm, Cytosol" "CAB015221: , HPA008399: AB_1852816, HPA017017: AB_1852818" "prognostic favourable (9.79e-4)" "unprognostic (6.62e-2)" "unprognostic (6.04e-2)" "unprognostic (1.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (4.25e-3)" "prognostic favourable (8.96e-4)" "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (3.38e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-1)" 27.9 33.2 11.2 21.5 16.7 55.7 19.0 24.1 15.6 27.2 29.1 13.1 16.7 27.6 27.6 14.1 53.4 22.7 14.5 19.2 10.6 12.2 27.2 19.4 68.0 33.4 12.3 11.3 49.9 28.2 21.2 31.8 11.3 13.3 29.6 17.8 20.7 21.1 16.1 20.6 23.6 41.2 21.5 13.3 44.3 22.1 13.7 11.5 29.2 38.8 22.3 43.1 30.1 25.2 20.6 35.3 6.1 84.2 14.2 9.0 54.6 23.5 25.4 35.7 21.3 31.0 34.7 15.6 9.9 29.3 19.6 22.8 18.6 20.5 52.9 12.4 14.7 31.1 29.2 40.3 26.8 18.1 28.3 19.4 16.3 22.5 18.3 10.2 11.8 33.0 34.0 27.0 33.1 38.7 11.8 9.3 28.2 16.2 26.8 31.5 41.6 34.5 25.2 26.6 30.5 35.9 30.1 18.5 21.9 20.0 23.4 21.4 29.0 12.5 13.8 8.3 14.0 11.8 10.7 12.6 21.8 24.5 5.9 18.6 6.5 0.4 76.0 2.2 4.5 84.2 8.4 15.1 6.3 5.8 35.3 20.6 9.0 6.7 6.1 14.2 73.2 8.7 6.3 54.6 11.2 16.7 24.1 15.6 10.6 12.2 12.3 11.3 13.3 11.5 LYZ ENSG00000090382 Lysozyme P61626 12 69348341-69354234 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 490.0;salivary gland: 1017.8" "Group enriched" "Detected in some" 6 "Hep G2: 126.5;THP-1: 65.3;U-937: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 490.0;myeloid DC: 308.1" "Group enriched" "Detected in all" 18 "dendritic cells: 308.1;monocytes: 490.0" "Not detected" "Not detected" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" 1500000000 2600000000 "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: , HPA066182: " "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favourable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 19.1 2.4 1.7 42.1 1.8 187.0 2.9 1.6 1.6 2.9 52.5 2.0 0.1 72.4 2.3 6.9 3.9 3.4 105.0 15.4 1.8 1.8 4.8 4.8 81.0 57.2 2.1 0.0 4.5 5.0 0.0 1.8 8.3 0.9 2.4 5.0 2.7 1017.8 2.8 1.8 2.1 95.0 1.8 2.5 34.2 212.1 1.6 0.5 24.5 2.4 207.7 75.7 6.6 2.4 1.6 308.1 21.9 490.0 2.3 1.1 407.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.2 0.8 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 0.1 126.5 0.0 14.8 7.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 14.4 0.3 0.0 0.2 0.2 2.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 65.3 0.0 0.0 0.3 0.3 0.1 0.3 0.1 0.1 0.0 70.7 0.0 7.5 490.0 5.9 0.7 102.3 1.1 1.6 0.4 0.5 308.1 0.4 0.4 0.4 21.9 2.3 17.6 6.5 0.6 407.9 1.7 1.8 1.6 1.6 1.8 1.8 2.1 0.0 0.9 0.5 LYZL1 "LYC2, MGC33408" ENSG00000120563 "Lysozyme like 1" Q6UWQ5 10 29289061-29318328 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 371 "testis: 39.5" "Group enriched" "Detected in some" 11 "A549: 1.5;HEK 293: 1.1;Hep G2: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "unprognostic (1.88e-1)" "unprognostic (8.40e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYZL2 ENSG00000151033 "Lysozyme like 2" Q7Z4W2 10 30611779-30629762 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "testis: 34.2" "Cell line enriched" "Detected in some" 6 "SK-BR-3: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "unprognostic (2.83e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYZL6 "LYC1, PRO1485, TKAL754" ENSG00000275722 "Lysozyme like 6" O75951 17 35934518-35943699 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 51 "testis: 33.2" "Cell line enriched" "Detected in single" 5 "NB-4: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025734, HPA053073" Enhanced "Secreted in male reproductive system" "HPA025734: AB_1853444, HPA053073: " 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 MAN1A1 ENSG00000111885 "Mannosidase alpha class 1A member 1" P33908 6 119177209-119349761 "Enzymes, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.2" "Cell line enhanced" "Detected in many" "ASC diff: 59.0;Hep G2: 41.4;Karpas-707: 46.2;U-266/70: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037058, HPA053198, HPA063561" Uncertain Supported "Golgi apparatus" 390000000 "Golgi apparatus" "CAB037058: AB_477183, HPA053198: , HPA063561: " "unprognostic (1.50e-1)" "unprognostic (7.36e-3)" "unprognostic (4.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.33e-3)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "unprognostic (1.68e-3)" "unprognostic (4.62e-1)" "unprognostic (2.37e-2)" "unprognostic (3.49e-2)" "unprognostic (2.25e-1)" "unprognostic (6.89e-2)" "unprognostic (3.40e-1)" 41.8 19.8 5.8 10.5 17.4 8.1 32.2 1.5 7.9 12.3 23.3 3.2 3.6 17.4 11.3 12.0 10.6 9.5 22.0 10.4 5.0 3.3 23.4 74.2 16.4 16.8 2.8 5.7 10.3 22.0 3.4 6.4 26.1 3.7 14.7 9.9 10.5 41.0 5.3 7.1 9.6 36.3 19.7 3.5 20.9 10.0 8.7 3.7 8.8 15.2 10.3 9.1 21.2 36.4 1.4 5.5 6.0 1.1 1.9 4.7 0.6 0.0 0.0 0.7 0.0 59.0 26.1 1.4 1.4 8.6 1.0 2.6 4.0 0.5 8.8 0.0 5.4 0.1 1.5 0.0 1.3 13.0 4.0 7.3 0.8 41.4 5.9 0.0 3.7 17.8 1.1 8.8 5.4 0.7 25.5 46.2 8.3 1.2 0.3 0.0 0.4 2.1 2.4 0.9 13.3 2.8 7.3 3.0 4.4 0.0 0.1 0.0 2.1 0.9 5.1 3.6 3.3 6.7 3.2 62.4 8.8 17.4 10.7 0.1 2.1 6.0 0.6 2.0 2.4 1.1 4.7 1.4 1.3 1.3 0.6 0.9 0.8 1.9 3.8 1.9 0.9 5.5 1.4 0.6 5.8 17.4 1.5 7.9 5.0 3.3 2.8 5.7 3.7 3.7 MAN1A2 MAN1B ENSG00000198162 "Mannosidase alpha class 1A member 2" O60476 1 117367449-117528872 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "placenta: 122.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034559, HPA057364" Enhanced Enhanced "Golgi apparatus" 1100000 "Golgi apparatus" "HPA034559: AB_10671229, HPA057364: " "unprognostic (2.24e-1)" "unprognostic (1.20e-1)" "unprognostic (2.92e-3)" "unprognostic (2.15e-1)" "unprognostic (3.11e-2)" "unprognostic (9.70e-2)" "unprognostic (1.95e-2)" "unprognostic (8.01e-2)" "unprognostic (8.19e-3)" "prognostic favourable (4.08e-4)" "unprognostic (1.41e-1)" "unprognostic (4.38e-2)" "unprognostic (6.84e-2)" "unprognostic (1.45e-1)" "unprognostic (7.39e-2)" "unprognostic (1.17e-1)" "unprognostic (5.08e-2)" 11.1 9.7 13.9 9.1 15.8 3.8 9.7 11.9 15.2 14.4 10.7 8.5 9.4 8.1 15.8 10.7 11.5 12.2 9.2 11.0 11.2 9.2 11.8 16.4 8.1 9.9 12.0 13.9 11.2 27.4 21.7 9.6 122.4 11.3 11.2 9.5 8.3 11.1 10.5 10.5 7.5 9.0 13.7 10.4 10.4 10.3 10.1 14.4 16.1 19.4 6.9 9.8 13.6 9.8 3.7 4.4 4.0 2.7 6.0 9.8 2.4 14.1 6.2 10.6 9.1 14.0 16.9 34.1 11.8 18.5 5.3 5.0 4.7 8.2 10.6 21.9 15.1 8.5 4.9 10.0 12.1 13.3 7.4 6.3 8.7 5.2 8.5 9.9 14.5 11.3 10.8 8.1 7.1 15.8 10.1 16.4 11.1 27.6 6.0 3.1 5.4 6.5 5.4 23.1 7.2 7.3 19.4 5.8 8.5 11.7 12.6 9.3 6.2 6.3 15.0 12.1 9.9 8.5 12.0 11.2 7.6 7.2 15.9 7.9 28.5 1.3 2.7 4.0 5.2 2.1 6.2 3.3 4.3 4.3 2.3 3.7 3.6 5.2 2.1 6.0 1.7 4.4 9.8 2.4 13.9 15.8 11.9 15.2 11.2 9.2 12.0 13.9 11.3 14.4 MAN1B1 "ERManI, MANA-ER, MRT15" ENSG00000177239 "Mannosidase alpha class 1B member 1" Q9UKM7 9 137086927-137109187 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051516 Approved Uncertain Vesicles 540000 Vesicles "HPA051516: " "unprognostic (1.21e-2)" "unprognostic (4.66e-1)" "unprognostic (1.25e-3)" "unprognostic (4.67e-3)" "unprognostic (2.27e-1)" "unprognostic (3.70e-3)" "prognostic unfavourable (1.45e-4)" "unprognostic (1.59e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-2)" "unprognostic (5.93e-3)" "unprognostic (1.75e-1)" "unprognostic (3.55e-2)" "unprognostic (2.28e-1)" "unprognostic (5.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.44e-3)" 20.4 25.4 19.7 13.5 23.7 9.8 18.6 21.6 36.1 24.3 21.6 24.5 20.6 19.8 22.7 28.1 23.1 28.9 25.9 19.5 20.5 21.5 24.3 32.7 20.4 19.9 18.6 25.2 24.2 32.6 23.6 25.1 30.8 18.0 21.2 12.0 22.0 32.7 23.1 12.2 25.4 17.8 18.5 16.4 22.2 21.8 30.3 18.2 19.9 25.1 12.7 19.3 21.0 16.0 13.0 23.0 16.3 24.4 18.0 21.9 18.5 7.2 17.1 5.9 16.9 22.5 19.4 19.8 12.3 26.1 16.5 14.6 8.3 22.9 6.6 41.4 20.6 25.0 3.5 11.9 3.0 9.1 6.0 2.9 15.4 9.6 21.2 5.1 11.4 22.9 22.6 9.6 8.1 10.9 8.0 10.9 11.6 14.7 5.4 12.1 7.9 17.2 3.1 10.0 20.9 13.2 3.6 6.9 6.2 18.2 19.4 12.6 21.5 10.9 15.3 24.4 9.1 18.0 14.4 4.4 3.6 4.3 29.4 6.5 21.0 7.9 20.1 16.3 21.9 21.8 20.5 13.0 17.3 20.6 23.0 11.0 17.0 17.0 5.9 18.0 24.4 16.1 21.5 18.5 19.7 23.7 21.6 36.1 20.5 21.5 18.6 25.2 18.0 18.2 MAN1C1 HMIC ENSG00000117643 "Mannosidase alpha class 1C member 1" Q9NR34 1 25617468-25786207 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 12.5;HSkMC: 46.0;U-266/70: 13.7" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 8.3" "Lineage enriched" "Detected in many" 5 "T-cells: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048352 Uncertain Uncertain Nucleoplasm,Vesicles 1200000 "Nucleoplasm, Vesicles" "HPA048352: " "unprognostic (2.75e-1)" "unprognostic (5.45e-3)" "unprognostic (5.71e-3)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (8.90e-3)" "unprognostic (4.78e-2)" "prognostic favourable (7.55e-4)" "unprognostic (1.80e-1)" "unprognostic (5.70e-2)" "prognostic favourable (4.79e-4)" "unprognostic (2.51e-1)" "unprognostic (9.09e-3)" "unprognostic (3.18e-2)" "unprognostic (7.23e-2)" "unprognostic (7.44e-2)" "unprognostic (5.18e-2)" 4.6 4.5 4.2 3.0 3.8 0.0 2.2 9.9 8.8 8.6 3.6 1.2 6.6 2.5 2.4 3.9 7.3 3.4 5.2 3.2 10.3 12.1 3.2 4.0 4.2 7.1 0.7 4.4 7.8 8.3 7.2 1.2 1.8 7.5 0.9 2.7 1.9 8.0 6.0 7.0 3.1 1.0 10.7 3.2 4.3 4.0 1.0 0.6 1.1 1.6 0.8 8.3 1.1 0.0 0.1 12.5 2.6 9.3 7.3 3.6 0.1 2.4 0.6 0.2 0.2 0.0 0.1 0.1 0.9 0.1 1.1 0.1 0.2 3.9 0.5 0.2 0.1 0.0 1.1 2.1 5.2 46.0 0.2 0.2 0.0 0.0 0.0 0.5 0.0 0.6 0.0 2.3 3.2 0.0 0.2 7.7 0.2 0.1 0.2 7.3 0.2 0.3 1.9 0.6 1.0 1.5 0.0 0.0 0.7 8.4 0.3 13.7 0.0 0.0 1.9 4.4 0.6 0.4 1.6 0.7 0.6 1.0 0.8 0.4 3.6 1.6 0.6 1.0 8.3 4.8 1.1 0.8 1.3 0.4 0.8 1.1 MAN2A1 "GOLIM7, MANA2" ENSG00000112893 "Mannosidase alpha class 2A member 1" Q16706 5 109689366-109869625 "Enzymes, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022377, HPA026896" Enhanced Supported "Golgi apparatus" 70000000 "Golgi apparatus" "CAB022377: , HPA026896: AB_1853512" "unprognostic (1.62e-2)" "unprognostic (4.06e-2)" "unprognostic (1.25e-2)" "unprognostic (6.96e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (4.20e-2)" "unprognostic (3.91e-1)" "unprognostic (2.90e-2)" "unprognostic (4.73e-2)" "unprognostic (1.23e-1)" "unprognostic (6.77e-3)" "unprognostic (2.03e-2)" "unprognostic (1.20e-2)" "unprognostic (1.11e-3)" "unprognostic (5.31e-3)" 7.6 17.5 10.9 7.7 21.8 5.7 7.4 1.9 13.2 8.4 11.2 46.8 2.4 17.2 9.2 1.8 7.7 6.2 10.6 4.2 11.7 4.8 9.5 20.7 8.5 7.8 29.9 10.4 7.5 16.7 20.1 3.4 8.7 19.8 4.7 11.9 5.6 9.0 6.0 8.7 7.0 14.4 11.2 23.1 6.9 8.9 7.5 30.6 15.0 9.0 1.8 7.8 10.9 6.2 3.3 2.7 5.8 6.7 0.9 5.5 1.6 7.2 6.7 8.4 3.6 16.1 14.2 31.4 16.1 26.6 9.2 16.6 7.9 11.7 5.2 10.4 20.9 8.6 4.5 16.7 20.1 5.6 3.4 10.6 5.0 7.2 9.1 4.8 5.8 12.1 6.9 14.7 19.5 18.1 2.8 30.5 21.6 3.6 9.0 1.3 6.0 2.4 3.5 13.1 23.0 7.3 11.5 1.2 1.1 7.6 6.8 4.6 6.7 4.2 19.3 18.2 8.0 9.8 10.4 16.3 21.1 4.4 14.0 6.2 10.1 5.8 2.9 0.9 3.0 3.8 1.9 3.3 4.5 4.9 2.7 2.9 5.5 4.8 2.1 0.9 6.7 2.5 4.1 1.6 10.9 21.8 1.9 13.2 11.7 4.8 29.9 10.4 19.8 30.6 MAN2A2 "HsT19662, MANA2X" ENSG00000196547 "Mannosidase alpha class 2A member 2" P49641 15 90902218-90922584 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.4;neutrophil: 10.0" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077930 Approved "Cytoplasmic bodies" 30000000 "Cytoplasmic bodies" "HPA077930: " "unprognostic (5.17e-2)" "unprognostic (9.80e-2)" "unprognostic (2.43e-2)" "unprognostic (2.41e-1)" "unprognostic (2.58e-1)" "unprognostic (1.86e-2)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "unprognostic (3.41e-1)" "unprognostic (2.27e-1)" "unprognostic (5.06e-3)" "unprognostic (1.09e-2)" "prognostic unfavourable (8.95e-4)" "unprognostic (7.55e-3)" "unprognostic (1.13e-1)" "unprognostic (8.36e-2)" "unprognostic (2.33e-2)" 17.8 12.1 15.9 11.5 24.3 58.1 17.3 33.7 31.2 7.2 9.9 52.4 6.3 12.0 8.9 9.8 7.6 8.0 9.4 22.7 17.8 14.0 8.1 16.7 13.3 12.4 31.6 19.7 9.7 24.0 13.0 15.2 12.4 31.0 9.2 9.0 17.2 20.6 12.6 41.8 14.8 13.0 7.6 33.1 19.1 12.4 12.7 28.3 3.8 13.8 2.7 9.1 7.5 10.7 1.5 2.1 10.0 3.2 0.1 1.4 1.5 5.7 5.9 4.2 10.0 12.7 3.4 8.2 4.2 3.9 4.4 3.4 4.8 4.3 0.8 10.4 4.9 6.5 4.4 2.4 2.7 14.2 10.4 39.2 9.0 3.2 4.2 5.7 21.3 2.5 4.6 5.3 4.3 5.7 14.7 5.1 2.0 7.8 3.7 11.3 1.4 1.8 5.1 4.0 6.0 5.5 13.8 10.2 5.9 5.8 10.9 8.2 5.1 18.7 4.9 3.6 3.9 4.4 5.5 8.0 24.4 2.1 4.2 8.3 6.1 8.4 1.6 0.6 1.4 1.1 0.9 1.0 0.6 0.8 0.3 1.5 0.4 0.4 10.0 0.1 3.2 2.1 1.3 1.5 15.9 24.3 33.7 31.2 17.8 14.0 31.6 19.7 31.0 28.3 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 42.1;intermediate monocyte: 39.4;myeloid DC: 35.2;non-classical monocyte: 28.4;plasmacytoid DC: 41.9" "Group enriched" "Detected in all" 5 "dendritic cells: 41.9;monocytes: 42.1" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" 3400000 "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavourable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 25.2 15.6 7.9 26.7 11.0 33.4 24.4 4.4 7.0 10.5 15.0 14.0 8.6 14.2 15.3 16.5 12.2 13.4 16.4 19.4 6.4 4.4 13.6 16.3 30.2 68.6 10.0 4.7 12.2 21.7 9.1 7.2 15.8 8.6 13.7 10.6 12.0 22.0 8.1 7.7 18.0 20.0 10.2 11.7 51.3 19.5 6.3 8.2 22.1 11.3 7.8 30.0 18.7 11.2 7.7 41.9 6.5 42.1 2.7 8.4 26.0 16.3 8.4 8.6 10.1 28.8 19.3 24.3 12.2 25.8 10.9 10.7 6.7 6.9 18.0 14.8 9.6 12.9 4.4 8.1 5.2 8.9 13.4 6.2 4.2 10.9 14.6 41.0 42.9 23.0 16.1 6.1 7.7 10.3 7.9 13.6 5.7 12.8 5.5 23.1 7.1 10.7 12.8 11.8 8.9 12.8 19.0 2.7 8.4 12.1 10.4 19.8 16.0 25.4 13.5 14.8 6.1 14.4 11.4 18.2 20.0 8.9 10.0 40.5 16.5 2.2 42.1 6.2 7.5 39.4 8.4 7.7 6.9 6.7 35.2 6.5 3.8 3.8 6.5 2.7 28.4 41.9 6.8 26.0 7.9 11.0 4.4 7.0 6.4 4.4 10.0 4.7 8.6 8.2 MAN2B2 KIAA0935 ENSG00000013288 "Mannosidase alpha class 2B member 2" Q9Y2E5 4 6575175-6623362 "Enzymes, Plasma proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" 11000000 "unprognostic (1.30e-1)" "unprognostic (3.32e-1)" "unprognostic (1.28e-1)" "prognostic favourable (7.59e-4)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.72e-1)" "unprognostic (6.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-3)" "unprognostic (2.18e-1)" 21.3 15.4 12.4 15.6 23.2 15.7 16.7 5.1 26.8 17.3 14.3 16.2 12.1 15.9 20.0 21.5 13.9 18.1 24.7 23.2 11.6 14.2 15.8 32.4 20.1 19.4 13.7 11.4 30.4 26.0 10.8 19.2 17.0 14.3 20.6 9.8 22.2 18.6 15.2 7.8 13.5 15.9 14.5 11.6 19.7 20.9 8.7 13.4 16.6 27.3 10.4 18.4 20.7 20.7 5.0 8.4 13.4 15.7 6.0 12.0 9.1 8.1 7.4 1.5 10.1 22.2 15.5 9.5 16.7 19.5 8.2 11.2 4.3 15.5 4.1 8.0 18.0 8.3 0.5 5.2 4.5 4.8 4.2 5.4 5.4 4.8 9.7 10.1 25.3 20.3 5.3 6.5 1.7 9.5 2.3 10.6 10.6 5.0 4.9 6.5 1.8 5.7 5.0 7.0 4.8 4.3 8.2 2.5 2.7 11.1 6.7 4.2 13.3 13.7 17.2 14.9 4.6 18.5 10.5 4.4 3.8 2.2 17.4 12.0 12.8 13.1 8.5 13.4 12.0 13.0 9.3 4.4 7.4 10.9 8.4 5.0 6.9 8.7 10.7 6.0 15.7 3.2 10.1 9.1 12.4 23.2 5.1 26.8 11.6 14.2 13.7 11.4 14.3 13.4 MAN2C1 "MANA, MANA1" ENSG00000140400 "Mannosidase alpha class 2C member 1" Q9NTJ4 15 75355207-75368630 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040627, HPA067407" Uncertain Enhanced Nucleoplasm 9000 Nucleoplasm "HPA040627: AB_10795490, HPA067407: " "unprognostic (4.68e-2)" "unprognostic (1.95e-1)" "unprognostic (3.84e-3)" "unprognostic (3.48e-2)" "unprognostic (3.85e-1)" "unprognostic (3.00e-2)" "unprognostic (1.26e-2)" "unprognostic (6.26e-2)" "unprognostic (2.47e-1)" "unprognostic (5.02e-2)" "unprognostic (1.06e-2)" "unprognostic (3.40e-2)" "unprognostic (4.87e-3)" "unprognostic (9.56e-2)" "unprognostic (1.33e-1)" "unprognostic (2.91e-1)" "unprognostic (1.39e-3)" 29.9 28.8 22.6 20.4 26.0 30.0 24.6 27.5 25.5 25.1 25.1 26.8 23.8 22.9 27.8 27.5 20.2 24.2 23.3 28.2 18.3 12.9 22.9 21.4 25.2 17.0 23.0 28.3 32.8 22.3 28.2 30.6 22.4 18.3 24.9 14.2 30.8 25.6 20.2 37.9 30.9 27.7 20.0 15.0 28.1 23.0 28.8 19.9 21.0 34.7 15.3 19.5 21.1 21.3 2.3 15.7 2.6 16.2 3.9 7.3 8.5 5.4 13.1 10.9 7.8 12.5 10.9 13.6 12.7 12.0 6.7 5.6 9.1 18.8 2.6 7.5 9.3 16.9 6.0 8.6 4.3 15.0 13.2 17.2 24.8 8.9 18.5 11.0 2.7 12.9 8.7 6.3 7.9 15.6 9.9 14.2 5.4 10.6 5.4 12.5 4.6 5.5 7.6 5.5 16.4 8.7 25.5 6.5 11.8 8.1 12.3 5.7 12.2 12.9 30.4 14.1 9.8 9.8 12.5 14.2 3.5 4.3 9.1 12.7 13.9 2.6 13.3 2.0 7.2 16.2 6.8 2.3 5.3 5.2 15.7 2.0 7.3 5.1 1.4 3.9 12.4 6.4 7.0 8.5 22.6 26.0 27.5 25.5 18.3 12.9 23.0 28.3 18.3 19.9 MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053478 Approved Supported Vesicles "Intracellular and membrane" 12000000 Vesicles "HPA053478: " "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.70e-1)" "prognostic unfavourable (7.56e-5)" "unprognostic (4.11e-2)" "prognostic unfavourable (3.74e-6)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (7.12e-2)" "unprognostic (4.81e-2)" "unprognostic (2.13e-1)" 12.7 23.5 8.5 12.2 11.9 8.6 17.1 13.4 8.4 12.1 9.9 12.9 11.7 8.1 11.6 13.6 9.3 11.0 15.5 12.1 8.7 8.6 11.8 10.3 17.7 20.2 15.1 6.2 16.7 18.1 25.1 18.4 25.0 10.8 12.0 10.8 12.4 27.4 11.4 5.4 7.8 14.0 14.2 15.3 21.3 14.4 4.6 13.5 9.4 19.2 3.6 12.8 17.9 12.6 3.9 9.5 25.2 11.6 3.6 3.1 3.9 7.3 4.1 2.0 1.9 39.0 18.1 5.1 5.1 10.1 2.2 4.4 5.3 8.5 7.9 6.9 7.1 3.5 5.2 11.3 1.8 5.5 2.1 4.5 4.6 8.1 11.9 8.3 20.5 15.4 19.3 9.5 7.9 4.1 7.5 8.2 8.0 3.3 2.0 8.0 2.8 3.4 4.1 4.7 2.2 6.4 8.7 1.3 1.0 6.1 10.5 7.9 15.0 5.7 3.1 6.1 3.0 13.6 2.7 4.3 9.0 0.8 11.0 3.7 4.4 6.2 11.5 25.2 1.8 10.6 1.4 3.8 3.1 2.0 9.5 3.9 3.0 2.0 10.1 3.6 11.6 2.3 1.6 3.9 8.5 11.9 13.4 8.4 8.7 8.6 15.1 6.2 10.8 13.5 MANEA "FLJ12838, mandaselin" ENSG00000172469 "Mannosidase endo-alpha" Q5SRI9 6 95577543-95609457 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011046, HPA011069" Enhanced Supported "Golgi apparatus" 87000 "Golgi apparatus" "HPA011046: AB_1079303, HPA011069: AB_1079304" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "prognostic favourable (3.04e-4)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (5.03e-2)" "unprognostic (2.98e-3)" "unprognostic (2.74e-1)" "unprognostic (5.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (9.07e-2)" "unprognostic (2.86e-3)" "unprognostic (5.18e-2)" "unprognostic (3.08e-1)" "unprognostic (9.68e-2)" "unprognostic (7.47e-2)" 18.0 8.1 6.0 6.7 6.9 2.4 14.4 8.3 6.0 9.6 9.5 5.0 5.8 7.7 7.5 8.2 11.5 7.2 7.1 9.3 6.5 6.2 14.6 44.9 9.8 12.3 8.9 6.7 10.4 8.0 10.9 13.5 7.4 7.8 9.2 8.0 4.5 8.1 7.6 3.8 5.9 9.5 6.0 11.6 13.2 10.7 7.1 6.9 17.9 11.7 5.9 9.7 11.2 7.5 6.6 3.4 8.5 5.7 3.8 10.4 3.3 3.7 3.2 12.2 9.9 20.3 23.9 4.7 10.6 9.7 6.2 9.3 3.6 9.5 7.2 13.2 6.8 6.2 8.4 7.0 14.2 12.4 7.6 9.8 3.0 5.9 7.1 12.7 8.7 23.6 8.2 7.3 5.1 14.4 15.0 16.8 13.1 2.6 7.4 5.4 1.8 3.2 8.9 12.2 10.7 9.4 6.6 9.8 5.3 5.9 4.3 3.7 6.8 12.0 13.0 6.2 4.4 11.1 10.3 12.6 7.4 8.9 11.0 11.2 14.0 8.5 3.3 1.9 4.8 5.7 6.8 6.6 5.9 5.5 3.4 3.3 6.9 4.6 0.7 3.8 4.9 1.3 10.4 3.3 6.0 6.9 8.3 6.0 6.5 6.2 8.9 6.7 7.8 6.9 MASP2 MASP1P1 ENSG00000009724 "Mannan binding lectin serine peptidase 2" O00187 1 11026523-11047233 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 98 "liver: 185.1" "Cell line enriched" "Detected in many" 7 "Hep G2: 20.1" "Cancer enriched" "Detected in some" 71 "liver cancer: 41.9" "Region enriched" "Detected in single" 4 "cerebellum: 1.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" 339700000 880000000 "Golgi apparatus" "HPA029313: AB_10669654, HPA029314: AB_10670029" "unprognostic (7.00e-2)" "unprognostic (8.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.89e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "prognostic favourable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (3.13e-2)" "unprognostic (4.04e-2)" "unprognostic (6.90e-3)" "unprognostic (8.30e-4)" "unprognostic (7.14e-2)" "unprognostic (3.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-4)" 0.3 0.2 0.3 0.4 0.3 1.8 0.3 1.7 0.5 0.3 0.3 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.1 0.3 185.1 0.3 0.6 0.3 0.3 0.5 0.4 0.0 0.3 0.3 0.3 0.3 0.0 0.3 0.7 0.3 1.4 1.4 0.5 0.3 0.3 0.6 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 1.4 1.2 1.2 0.2 0.8 1.3 0.0 0.5 0.3 2.9 1.6 0.0 0.1 0.4 0.8 0.0 0.0 0.0 1.3 1.1 2.3 0.6 0.0 0.7 0.0 0.0 0.0 0.6 2.3 1.4 2.5 20.1 0.0 2.1 1.6 0.0 0.0 0.1 0.0 0.0 0.8 0.5 0.0 0.6 0.6 1.1 0.4 0.6 1.8 1.0 0.5 0.0 1.4 1.8 0.7 0.9 0.5 0.5 0.6 1.3 1.1 0.9 0.6 1.0 0.6 0.7 1.1 1.7 0.6 1.9 0.4 1.2 0.2 1.1 0.7 0.1 1.0 0.7 0.9 0.8 0.5 1.4 1.3 1.3 0.2 0.8 0.2 1.2 0.1 0.0 0.3 0.3 1.7 0.3 0.3 0.1 0.3 0.3 0.3 0.3 MBTPS1 "KIAA0091, PCSK8, S1P, SKI-1" ENSG00000140943 "Membrane bound transcription factor peptidase, site 1" Q14703 16 84053761-84116906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056109 Supported "HPA056109: " "unprognostic (1.50e-1)" "unprognostic (9.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (2.50e-1)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "prognostic favourable (2.21e-5)" "unprognostic (2.62e-1)" "unprognostic (2.92e-1)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" 26.6 25.3 15.2 17.9 32.0 13.2 27.2 29.9 30.2 27.5 23.6 20.5 21.5 15.8 33.5 22.2 18.8 29.2 20.4 31.5 15.7 18.2 23.4 28.9 22.1 17.1 14.8 15.9 34.3 32.6 47.5 38.7 28.5 15.9 24.0 21.2 33.1 29.7 26.8 16.2 18.7 19.0 25.9 11.4 21.8 23.5 17.7 16.1 24.0 36.7 16.7 23.2 26.1 19.6 10.9 11.5 12.8 14.3 14.4 16.7 15.4 15.2 19.4 17.5 24.2 41.2 33.5 13.7 25.7 39.9 22.8 17.3 13.7 22.7 14.7 26.8 36.9 16.9 15.9 17.9 25.4 13.2 17.9 10.7 18.8 19.2 19.9 25.9 23.7 34.4 25.9 21.0 18.1 29.6 13.9 13.0 13.8 26.5 14.2 14.5 16.2 13.9 18.5 9.3 10.6 18.5 12.7 13.3 16.7 49.7 13.8 19.2 43.2 23.9 31.4 23.7 17.4 14.1 12.1 16.5 30.5 28.2 17.3 15.8 14.4 6.6 14.3 12.8 15.8 12.1 16.2 10.9 13.6 14.7 11.5 9.9 16.7 14.8 4.1 14.4 9.8 6.4 8.7 15.4 15.2 32.0 29.9 30.2 15.7 18.2 14.8 15.9 15.9 16.1 MBTPS2 "KFSD, S2P" ENSG00000012174 "Membrane bound transcription factor peptidase, site 2" O43462 X 21839636-21885424 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Ichthyosis, Osteogenesis imperfecta, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005494, CAB009486" Approved Approved Nucleoplasm,Mitochondria,Cytosol "Nucleoplasm, Mitochondria, Cytosol" "CAB009486: AB_2140370, HPA005494: AB_1079329" "unprognostic (7.97e-3)" "unprognostic (9.12e-2)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (7.22e-2)" "unprognostic (3.32e-1)" "unprognostic (9.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (8.38e-2)" "unprognostic (7.76e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (3.05e-2)" 12.0 17.4 9.3 7.2 13.9 2.5 12.7 20.8 18.5 11.8 9.3 13.4 6.9 7.6 14.7 9.1 9.3 10.9 10.1 11.6 9.9 10.7 13.9 26.0 8.6 6.6 10.6 13.0 18.7 12.2 17.9 15.6 22.3 17.4 15.7 9.1 12.4 14.1 13.1 14.5 8.2 8.1 14.6 14.6 7.5 9.1 6.9 7.0 7.1 13.1 7.4 6.7 11.4 9.1 3.9 6.9 1.5 4.8 4.6 5.9 3.3 9.1 19.0 9.1 9.2 11.5 14.3 4.4 13.5 13.8 12.9 11.3 7.5 12.6 7.9 7.1 14.4 8.6 12.5 7.8 16.0 5.9 10.0 3.9 12.1 6.2 15.8 8.4 3.9 13.5 8.4 19.5 14.4 9.9 10.9 8.9 14.7 5.7 3.4 4.4 8.5 14.1 4.3 16.9 8.8 9.0 4.6 2.2 18.7 19.1 12.1 16.7 16.3 7.2 11.7 16.3 3.8 23.7 10.1 10.9 13.8 3.8 18.1 3.5 15.6 0.1 4.3 1.5 4.5 4.8 4.2 3.9 3.5 4.1 6.9 3.8 4.7 5.6 0.5 4.6 4.8 4.8 5.9 3.3 9.3 13.9 20.8 18.5 9.9 10.7 10.6 13.0 17.4 7.0 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598223-127622436 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 69.9" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000303, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm 8600 Nucleoplasm "CAB000303: AB_322519, HPA031495: AB_2673904, HPA031496: " "unprognostic (2.43e-1)" "prognostic favourable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavourable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 2.9 3.7 2.1 24.3 4.0 32.5 3.5 6.7 3.2 4.7 7.1 3.3 2.2 4.7 4.7 5.9 11.2 4.8 5.4 3.6 2.0 2.3 3.9 3.4 3.4 14.6 2.2 3.5 5.1 3.0 2.4 2.4 26.4 3.0 3.2 6.0 2.5 4.7 1.9 7.0 6.0 7.1 2.9 2.9 13.3 3.8 20.3 3.9 69.9 4.1 16.6 20.7 3.4 5.1 10.4 3.6 0.9 1.4 5.8 10.6 3.4 24.8 21.2 23.2 20.3 1.4 3.0 22.7 13.1 8.4 26.3 28.7 35.1 16.5 26.8 12.8 6.4 20.0 41.5 15.0 16.4 22.1 25.9 44.3 28.4 25.5 0.9 41.4 19.4 1.6 1.7 17.8 2.7 8.2 22.1 24.6 9.6 33.0 38.3 30.4 34.0 18.7 43.1 33.3 38.4 5.4 19.3 28.9 21.9 33.5 10.0 3.4 21.4 32.5 4.2 20.5 17.5 25.2 17.6 25.5 28.9 66.6 14.2 31.4 7.8 0.0 0.6 0.2 4.7 1.4 5.9 10.4 4.1 5.5 2.8 9.2 3.9 5.0 0.9 5.8 0.3 3.6 10.6 3.4 2.1 4.0 6.7 3.2 2.0 2.3 2.2 3.5 3.0 3.9 MCM3 ENSG00000112118 "Minichromosome maintenance complex component 3" P25205 6 52264009-52284881 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 82.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002162, HPA004789, HPA004790" Supported Enhanced Nucleoplasm 29000 Nucleoplasm "CAB002162: AB_564115, HPA004789: AB_1079336, HPA004790: AB_1079335" "unprognostic (9.14e-2)" "prognostic favourable (1.89e-4)" "unprognostic (2.37e-1)" "unprognostic (1.53e-2)" "unprognostic (2.14e-1)" "unprognostic (5.48e-3)" "prognostic unfavourable (1.40e-4)" "unprognostic (1.36e-1)" "prognostic unfavourable (4.40e-5)" "unprognostic (1.01e-3)" "unprognostic (2.96e-2)" "unprognostic (1.15e-1)" "unprognostic (8.35e-2)" "unprognostic (1.16e-2)" "unprognostic (1.00e-1)" "prognostic favourable (3.13e-5)" "unprognostic (1.34e-2)" 17.3 10.9 8.5 29.7 10.5 22.3 15.3 10.7 9.7 15.9 17.2 9.5 20.2 9.0 21.2 13.0 21.7 15.5 15.8 15.4 7.4 6.6 16.1 12.6 13.7 30.1 8.9 5.8 20.0 13.8 16.0 7.4 24.7 10.0 15.9 19.2 12.7 12.6 23.4 12.1 15.0 17.8 17.7 9.5 23.2 15.3 16.1 10.5 82.5 12.9 20.1 35.7 19.1 15.3 21.1 12.9 11.4 13.3 22.2 29.4 18.6 30.2 20.1 35.1 33.1 7.6 6.9 23.1 22.5 17.3 38.4 39.5 41.2 16.5 33.1 22.6 13.1 24.1 46.3 27.5 38.9 37.2 43.8 62.5 40.5 58.0 2.0 61.3 25.6 4.1 6.4 28.2 7.9 19.6 50.8 76.3 19.8 20.0 61.7 47.4 29.1 14.2 54.8 53.8 44.2 17.0 32.2 35.7 27.3 23.6 13.6 20.4 26.8 43.5 10.0 26.3 28.3 27.1 33.6 22.6 25.8 58.9 22.6 53.2 30.7 11.1 8.0 11.4 22.9 13.3 19.7 21.1 23.3 23.0 12.9 19.2 22.6 24.0 1.1 22.2 7.4 8.3 29.4 18.6 8.5 10.5 10.7 9.7 7.4 6.6 8.9 5.8 10.0 10.5 MCM4 "CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21" ENSG00000104738 "Minichromosome maintenance complex component 4" P33991 8 47960185-47978160 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 56.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004497, HPA004873, HPA031052" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB004497: AB_627916, HPA004873: AB_1079337, HPA031052: " "unprognostic (4.55e-2)" "unprognostic (3.16e-3)" "prognostic favourable (2.19e-4)" "prognostic unfavourable (2.84e-5)" "unprognostic (7.71e-2)" "unprognostic (1.05e-1)" "prognostic unfavourable (1.23e-4)" "unprognostic (1.12e-3)" "prognostic unfavourable (1.15e-4)" "unprognostic (2.65e-2)" "prognostic unfavourable (2.38e-4)" "unprognostic (5.16e-2)" "prognostic unfavourable (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.70e-2)" "unprognostic (1.40e-1)" 4.9 8.7 6.7 18.4 12.6 33.1 9.3 13.9 14.8 6.7 11.9 6.9 3.6 8.3 4.7 7.8 21.6 5.9 6.8 8.3 6.6 7.1 8.0 6.6 4.4 20.3 5.9 7.7 5.3 5.5 4.3 4.1 29.2 7.7 4.2 13.2 5.3 9.0 3.1 8.7 16.2 10.3 5.9 6.4 10.1 6.3 39.0 4.1 56.6 4.0 21.8 23.7 8.0 9.5 5.1 4.9 3.4 4.3 4.9 12.9 4.5 34.1 21.2 39.4 14.4 3.9 6.8 17.4 26.0 17.1 32.8 37.2 22.5 31.0 37.0 14.6 12.9 25.2 49.6 21.1 37.1 11.6 32.8 63.4 25.5 24.9 1.0 33.8 13.9 4.1 4.2 26.1 9.3 11.5 34.9 30.8 22.6 21.1 74.8 24.7 42.7 9.2 47.6 30.9 24.1 11.9 30.6 37.8 18.2 52.7 22.0 7.8 26.3 17.8 7.7 25.1 24.4 28.1 23.8 10.1 24.2 75.5 20.1 31.4 22.4 3.4 2.1 1.5 5.5 3.7 2.7 5.1 5.0 6.8 4.9 2.1 4.6 3.4 0.1 4.9 4.3 1.7 12.9 4.5 6.7 12.6 13.9 14.8 6.6 7.1 5.9 7.7 7.7 4.1 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400063-35425430 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.0;lymphoid tissue: 60.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: " "unprognostic (6.71e-2)" "prognostic favourable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavourable (1.78e-4)" "prognostic unfavourable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavourable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 12.1 4.9 6.1 27.5 9.0 57.0 9.1 6.7 5.7 10.4 11.5 12.3 5.0 9.5 10.8 10.8 15.8 8.7 9.4 5.2 4.4 3.4 6.8 8.0 9.3 31.1 8.8 3.7 17.9 10.8 6.2 3.6 19.3 5.8 7.2 8.3 6.5 8.9 5.1 8.8 10.3 16.7 6.0 7.8 31.2 8.4 16.4 8.8 60.6 9.0 17.7 33.0 8.7 9.6 46.8 30.9 19.0 26.0 21.3 32.9 24.0 38.9 28.3 22.4 22.8 2.1 4.4 19.6 26.0 13.8 38.9 37.0 18.8 19.4 25.8 15.1 13.2 19.4 22.3 20.6 12.5 20.8 41.0 36.8 28.4 37.5 0.7 75.9 33.3 2.4 1.9 23.2 6.3 17.2 22.7 38.6 14.7 32.1 61.8 25.3 29.7 16.8 70.0 31.7 32.5 7.7 22.6 17.3 18.4 35.8 14.4 8.0 15.0 29.0 10.1 39.3 29.9 24.4 26.8 21.5 26.4 48.5 25.4 28.7 30.0 19.0 20.7 14.5 18.4 24.1 13.1 46.8 16.1 19.4 27.1 37.0 13.1 14.8 9.9 21.3 26.0 30.9 32.9 24.0 6.1 9.0 6.7 5.7 4.4 3.4 8.8 3.7 5.8 8.8 MCM6 Mis5 ENSG00000076003 "Minichromosome maintenance complex component 6" Q14566 2 135839626-135876426 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 66.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004818, CAB009577" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB009577: AB_2266309, HPA004818: AB_1079339" "unprognostic (6.73e-2)" "unprognostic (6.68e-3)" "unprognostic (1.22e-3)" "unprognostic (3.60e-3)" "unprognostic (8.98e-2)" "unprognostic (4.34e-2)" "prognostic unfavourable (5.70e-7)" "unprognostic (1.71e-2)" "prognostic unfavourable (1.09e-5)" "unprognostic (2.36e-2)" "unprognostic (1.36e-2)" "unprognostic (3.53e-2)" "prognostic unfavourable (8.29e-12)" "unprognostic (2.84e-1)" "unprognostic (9.02e-2)" "unprognostic (7.42e-2)" "unprognostic (1.68e-1)" 11.3 6.3 7.2 17.7 8.4 23.1 9.5 12.3 9.4 9.1 11.9 5.1 2.9 8.7 10.4 8.8 12.6 8.7 7.6 6.0 5.0 5.5 6.8 7.0 8.5 23.9 4.9 8.0 10.9 4.3 6.2 3.4 10.9 5.9 8.6 12.2 6.2 6.9 6.7 8.2 8.9 16.7 10.4 7.2 14.1 8.0 13.2 3.7 66.3 5.1 11.4 27.5 10.8 9.8 5.5 9.4 5.3 4.0 7.0 13.9 5.6 23.0 14.2 31.0 19.7 6.7 8.7 12.2 16.8 12.8 19.6 21.9 29.0 17.7 40.4 12.4 12.2 13.7 31.3 15.4 21.0 20.7 21.6 40.1 21.1 9.1 3.1 48.1 17.9 5.1 2.0 14.3 4.4 13.3 28.6 34.2 14.4 23.6 58.7 35.4 27.9 14.3 29.1 37.1 37.0 9.8 20.4 19.5 16.6 22.2 10.6 10.6 12.2 30.3 6.5 13.7 11.4 14.7 12.7 20.5 33.4 53.2 19.1 36.8 16.2 5.3 1.4 0.9 7.6 4.0 7.1 5.5 10.5 9.2 4.6 3.2 9.6 11.8 0.8 7.0 3.6 9.4 13.9 5.6 7.2 8.4 12.3 9.4 5.0 5.5 4.9 8.0 5.9 3.7 MCM7 "CDC47, MCM2, PPP1R104" ENSG00000166508 "Minichromosome maintenance complex component 7" P33993 7 100092728-100101940 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002163, HPA003898, CAB016312" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB002163: AB_564113, CAB016312: AB_627235, HPA003898: AB_1853632" "unprognostic (1.87e-1)" "prognostic favourable (1.28e-4)" "unprognostic (1.36e-1)" "unprognostic (5.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.03e-2)" "prognostic unfavourable (2.18e-4)" "unprognostic (2.08e-2)" "unprognostic (5.79e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (9.34e-3)" "unprognostic (3.83e-2)" "unprognostic (5.41e-2)" "unprognostic (1.76e-1)" "unprognostic (1.32e-2)" "unprognostic (2.38e-1)" 8.6 5.2 17.5 13.6 21.7 37.3 11.2 20.0 20.6 8.2 14.2 19.2 15.0 10.4 16.0 6.3 10.7 8.6 9.9 5.1 18.1 12.4 5.5 8.5 7.4 22.4 23.7 9.5 12.6 13.1 7.5 10.3 10.7 15.5 10.0 15.7 7.2 9.2 9.2 11.5 10.1 10.3 11.7 23.5 10.7 7.8 14.9 22.3 7.5 9.4 4.1 28.2 10.3 10.0 7.3 5.7 1.9 5.7 7.6 9.0 6.0 24.5 28.4 31.3 23.6 3.0 4.0 16.0 14.9 18.1 41.7 44.5 21.6 25.9 41.6 14.3 10.6 19.4 45.9 21.7 35.3 21.3 39.3 26.5 15.9 14.9 1.6 44.9 17.2 2.8 4.1 30.6 18.4 15.8 50.6 34.1 21.1 52.4 76.3 18.4 27.4 20.5 41.1 45.9 50.7 8.1 14.9 20.5 31.2 23.6 21.9 7.4 10.1 18.8 6.7 15.8 28.6 30.8 29.6 14.3 24.3 74.8 10.9 36.1 28.1 1.8 2.5 1.9 8.1 4.1 6.2 5.3 5.7 7.9 5.5 7.3 5.9 5.7 1.6 7.6 5.7 5.7 9.0 6.0 17.5 21.7 20.0 20.6 18.1 12.4 23.7 9.5 15.5 22.3 MCM8 "C20orf154, dJ967N21.5, MGC119522, MGC119523, MGC12866, MGC4816, REC" ENSG00000125885 "Minichromosome maintenance 8 homologous recombination repair factor" Q9UJA3 20 5950652-5998977 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Disease mutation, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045141, HPA066433" Supported Nucleoplasm Nucleoplasm "HPA045141: , HPA066433: " "unprognostic (6.55e-2)" "unprognostic (2.46e-2)" "unprognostic (4.43e-1)" "unprognostic (2.22e-3)" "unprognostic (1.90e-1)" "unprognostic (5.78e-2)" "prognostic unfavourable (9.30e-8)" "unprognostic (5.21e-2)" "unprognostic (5.14e-2)" "unprognostic (2.50e-1)" "prognostic unfavourable (7.50e-4)" "unprognostic (6.74e-2)" "unprognostic (1.11e-2)" "unprognostic (5.53e-2)" "unprognostic (2.76e-1)" "unprognostic (2.66e-2)" "unprognostic (3.47e-1)" 4.9 5.4 7.3 11.0 7.6 11.2 9.3 17.9 12.7 5.4 6.2 3.1 12.0 5.4 5.9 3.9 6.6 4.3 2.7 11.3 4.8 2.2 4.3 3.1 6.3 9.6 10.6 5.1 5.0 5.6 5.1 4.8 5.4 7.1 5.9 6.0 3.5 5.1 7.2 11.2 6.1 6.1 7.0 8.3 6.1 5.6 21.9 7.7 8.8 4.4 7.0 9.5 6.0 6.1 1.8 1.7 3.3 0.7 1.9 3.0 0.4 18.9 14.8 12.8 12.9 3.4 4.1 11.3 15.6 6.3 12.2 14.7 16.2 12.0 19.4 4.7 5.2 20.4 21.2 12.3 22.1 5.3 8.7 21.4 7.1 15.7 0.5 22.5 3.3 1.9 2.0 20.6 8.5 5.7 21.8 19.1 12.5 5.3 11.6 11.8 17.1 8.7 14.2 21.7 7.8 3.1 7.6 9.5 10.1 15.9 17.7 9.5 11.4 8.0 3.8 21.7 18.1 11.7 22.6 8.2 20.5 32.9 4.4 14.6 17.8 3.3 0.5 1.7 1.8 0.5 3.0 1.8 1.1 2.1 0.1 1.7 1.1 1.7 2.1 1.9 0.7 1.7 2.0 0.4 7.3 7.6 17.9 12.7 4.8 2.2 10.6 5.1 7.1 7.7 MCM9 "C6orf61, dJ329L24.3, FLJ20170, MCMDC1, MGC35304" ENSG00000111877 "Minichromosome maintenance 9 homologous recombination repair factor" Q9NXL9 6 118813442-118935162 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031137 Approved Approved Nucleoplasm Nucleoplasm "HPA031137: AB_10602027" "unprognostic (3.11e-2)" "unprognostic (1.99e-1)" "unprognostic (4.33e-3)" "unprognostic (2.90e-1)" "unprognostic (2.78e-2)" "unprognostic (2.82e-1)" "unprognostic (3.00e-2)" "unprognostic (2.29e-1)" "unprognostic (3.61e-2)" "unprognostic (7.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (8.30e-2)" "unprognostic (2.16e-1)" "unprognostic (3.95e-1)" "unprognostic (2.26e-1)" "unprognostic (8.79e-2)" 8.6 7.2 5.9 11.9 8.4 14.5 17.7 5.2 6.9 9.4 11.2 8.2 9.8 7.3 9.0 16.0 10.2 8.6 8.2 6.6 5.9 4.0 9.3 7.6 15.6 12.1 11.5 4.7 8.7 12.2 11.9 11.2 13.8 6.3 10.5 8.4 7.0 11.8 8.7 4.2 9.8 12.6 10.9 5.7 10.2 7.3 7.9 8.1 27.0 13.1 7.1 9.9 9.6 10.5 3.1 5.2 8.0 5.3 10.2 6.4 3.9 4.6 7.4 11.8 12.7 5.3 5.3 9.1 4.4 7.8 6.5 8.3 6.0 8.3 14.0 5.5 7.5 14.0 8.2 4.7 9.1 8.2 11.3 11.1 8.7 5.9 3.1 11.9 7.5 5.8 5.6 6.6 7.7 6.2 13.4 6.5 4.2 9.7 10.5 9.6 5.8 3.3 8.4 7.4 3.7 6.6 9.3 10.2 7.4 7.7 5.7 4.0 8.4 16.9 6.3 5.1 4.6 3.6 6.4 8.6 7.2 16.6 6.6 9.8 6.0 7.2 4.5 8.0 4.9 5.3 3.8 3.1 3.0 5.0 5.2 3.0 3.6 3.5 5.4 10.2 3.2 3.7 6.4 3.9 5.9 8.4 5.2 6.9 5.9 4.0 11.5 4.7 6.3 8.1 MDP1 "FN6Pase, MGC5987" ENSG00000213920 "Magnesium dependent phosphatase 1" Q86V88 14 24213937-24216070 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003064, HPA070338" Uncertain Approved Nucleoplasm 34000 Nucleoplasm "HPA003064: AB_10602350, HPA070338: " "unprognostic (2.70e-1)" "unprognostic (3.68e-1)" "unprognostic (2.51e-1)" "unprognostic (2.11e-1)" "unprognostic (3.09e-1)" "unprognostic (5.46e-2)" "unprognostic (5.48e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "unprognostic (8.02e-2)" "unprognostic (2.00e-3)" "unprognostic (1.02e-1)" "prognostic favourable (5.96e-4)" "unprognostic (6.39e-2)" "unprognostic (1.32e-1)" "unprognostic (3.82e-1)" "unprognostic (3.19e-2)" 12.2 17.6 18.5 8.3 15.0 8.1 18.7 18.6 18.3 13.3 10.2 13.1 21.0 6.7 10.6 19.0 8.9 14.3 12.0 17.8 13.8 13.9 16.6 14.7 8.7 13.5 15.1 14.5 12.9 20.2 14.8 18.3 9.4 16.6 13.3 8.6 13.5 14.3 16.3 11.4 10.6 9.8 10.9 13.9 10.4 10.0 6.6 17.0 14.3 14.6 10.6 10.8 10.0 9.6 10.1 23.0 12.2 11.1 9.0 11.9 7.9 3.1 7.8 5.9 3.8 5.9 5.5 0.2 3.4 7.4 6.9 7.1 4.1 9.0 12.6 8.7 3.5 3.0 2.9 6.8 4.3 4.2 3.2 4.8 2.9 9.5 5.7 6.2 3.5 3.9 6.2 4.1 7.9 4.8 1.5 9.5 6.1 17.0 8.7 10.1 1.6 14.1 6.3 4.2 10.0 6.6 4.6 7.3 7.1 5.4 11.5 7.2 6.9 3.2 2.9 7.5 7.2 3.1 3.4 15.4 6.1 9.2 7.0 3.1 5.7 3.1 10.9 12.2 6.3 11.1 5.9 10.1 8.1 7.3 12.4 9.5 9.9 8.2 3.8 9.0 9.4 23.0 11.9 7.9 18.5 15.0 18.6 18.3 13.8 13.9 15.1 14.5 16.6 17.0 MEP1A PPHA ENSG00000112818 "Meprin A subunit alpha" Q16819 6 46793390-46839782 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 52 "intestine: 243.0" "Cell line enhanced" "Detected in some" "BEWO: 3.0;CACO-2: 6.9;Hep G2: 1.8;NB-4: 3.0;RPMI-8226: 3.4;SH-SY5Y: 2.1;U-2197: 2.0" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 38.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "myeloid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025163, HPA029416" Enhanced 990000 "CAB025163: , HPA029416: AB_10600823" "unprognostic (1.83e-1)" "unprognostic (2.81e-4)" "unprognostic (2.03e-1)" "unprognostic (8.53e-2)" "unprognostic (8.73e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-2)" "unprognostic (5.27e-4)" "unprognostic (2.05e-1)" "unprognostic (2.35e-2)" "unprognostic (1.42e-1)" "unprognostic (2.11e-1)" "unprognostic (1.11e-3)" "unprognostic (1.45e-1)" "unprognostic (1.91e-2)" "unprognostic (4.70e-3)" "unprognostic (1.68e-1)" 0.1 0.1 0.1 4.7 0.1 0.0 0.1 0.1 0.1 0.1 100.5 0.1 0.1 51.7 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.0 0.1 0.1 0.1 0.1 19.8 0.1 0.2 0.1 0.1 0.1 243.0 0.2 0.2 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 MEP1B ENSG00000141434 "Meprin A subunit beta" Q16820 18 32185069-32220404 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "intestine: 241.5" "Cell line enhanced" "Detected in some" "SCLC-21H: 10.3" "Group enriched" "Detected in some" 5 "pancreatic cancer: 3.0;stomach cancer: 0.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029119 Enhanced "Secreted to digestive system" 120000 "HPA029119: " "unprognostic (1.33e-1)" "unprognostic (6.72e-2)" "unprognostic (2.79e-2)" "unprognostic (1.00e-1)" "unprognostic (3.50e-4)" "unprognostic (1.27e-1)" "unprognostic (1.74e-2)" "unprognostic (4.30e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (8.31e-4)" "unprognostic (4.74e-2)" "unprognostic (3.39e-1)" "unprognostic (2.71e-1)" "unprognostic (3.39e-2)" "unprognostic (3.75e-2)" 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 0.1 78.8 0.0 0.0 54.5 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 1.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.1 241.5 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.1 0.4 0.3 0.3 0.0 1.4 0.5 0.2 0.0 0.0 0.5 0.6 0.0 2.0 1.0 0.3 0.2 0.1 0.5 1.4 1.7 0.5 0.0 0.2 0.0 0.0 0.0 0.7 0.9 1.1 0.7 0.6 0.4 1.3 0.3 0.0 0.7 0.0 0.1 0.4 1.1 0.2 0.0 1.9 1.3 4.0 1.3 0.0 1.8 1.7 2.9 0.0 0.7 10.3 2.3 0.8 0.2 0.3 0.4 3.0 0.9 1.3 0.8 3.4 0.0 0.5 2.2 0.5 2.6 0.0 0.5 0.0 0.3 0.3 1.0 0.1 1.3 1.1 0.7 1.4 0.4 0.1 1.2 0.3 0.2 0.0 0.1 0.2 0.5 0.5 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.0 0.0 METAP1 "KIAA0094, MAP1A, MetAP1A" ENSG00000164024 "Methionyl aminopeptidase 1" P53582 4 98995620-99062813 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025485, HPA037997, HPA037998" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" 11000 Cytosol "Nucleoplasm, Plasma membrane" "CAB025485: , HPA037997: , HPA037998: " "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "prognostic favourable (7.22e-4)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (2.15e-1)" "prognostic unfavourable (3.08e-5)" "unprognostic (1.09e-1)" "unprognostic (1.51e-3)" "unprognostic (2.05e-1)" "prognostic unfavourable (2.28e-5)" "unprognostic (2.00e-1)" "prognostic favourable (1.72e-4)" "unprognostic (5.50e-2)" "unprognostic (8.51e-2)" "unprognostic (1.15e-3)" "prognostic favourable (9.31e-4)" 12.1 8.3 10.0 16.0 10.1 11.8 18.6 9.2 13.8 16.0 17.9 7.0 22.9 13.4 24.1 25.9 37.2 14.0 12.3 27.9 9.5 7.1 14.3 13.7 10.7 12.6 7.9 9.8 11.3 13.0 7.8 14.4 9.2 9.9 19.1 19.3 7.5 19.0 21.5 27.2 16.4 15.2 27.8 10.1 13.9 11.6 46.8 8.1 27.0 10.8 21.8 19.1 36.6 22.6 12.7 11.7 10.4 11.1 12.5 19.2 10.8 21.7 21.5 18.9 20.2 15.0 24.1 21.0 31.2 20.1 26.7 25.5 24.1 32.5 32.2 12.5 25.2 21.9 33.1 31.2 37.1 22.5 15.8 28.8 15.7 25.8 16.3 38.9 24.1 17.3 22.7 22.6 24.1 21.9 22.5 19.5 28.5 16.5 34.0 18.6 23.2 17.5 22.4 29.5 17.2 42.8 28.2 25.9 15.3 10.4 32.3 12.3 12.4 14.9 17.8 21.6 27.5 19.7 27.1 14.1 19.9 25.5 18.6 19.9 21.4 10.4 9.4 4.2 14.9 11.1 19.2 12.7 15.4 14.5 11.7 10.1 15.1 13.5 2.3 12.5 10.7 5.8 13.4 10.8 10.0 10.1 9.2 13.8 9.5 7.1 7.9 9.8 9.9 8.1 METAP1D "MAP1D, Metap1l" ENSG00000172878 "Methionyl aminopeptidase type 1D, mitochondrial" Q6UB28 2 171999583-172082430 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030298, HPA030299" Uncertain Uncertain Vesicles Vesicles "HPA030298: AB_2673419, HPA030299: AB_10602421" "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (1.88e-1)" "unprognostic (5.83e-2)" "unprognostic (2.54e-2)" "unprognostic (7.90e-3)" "unprognostic (1.92e-3)" "unprognostic (1.07e-2)" "unprognostic (4.55e-1)" "unprognostic (7.07e-2)" "unprognostic (2.64e-2)" "unprognostic (8.19e-2)" "unprognostic (2.53e-3)" "unprognostic (3.44e-3)" "unprognostic (3.06e-2)" "unprognostic (5.48e-3)" "unprognostic (2.92e-2)" 7.1 7.5 7.2 8.0 8.4 6.3 8.2 6.7 9.2 6.5 6.1 9.6 6.5 5.0 9.0 6.4 5.2 10.3 4.5 6.4 6.0 4.9 5.4 8.3 3.6 8.1 9.3 7.1 18.9 23.8 5.5 13.8 4.1 8.6 8.3 7.1 7.3 9.7 10.3 13.8 7.1 5.9 10.0 7.2 8.6 6.3 5.9 9.5 2.1 5.6 6.3 6.7 5.4 5.7 2.5 0.5 0.2 1.2 1.2 3.6 0.7 3.3 2.6 3.9 13.0 5.8 7.5 8.0 3.8 3.9 6.2 3.9 6.0 4.4 1.7 7.0 4.0 6.1 8.5 6.7 6.3 5.9 10.1 9.4 6.9 7.9 6.2 5.5 2.5 5.7 10.6 6.1 9.9 3.5 13.5 4.8 4.6 4.1 3.1 7.5 7.1 3.2 7.1 3.4 3.0 4.4 4.6 8.1 3.1 2.7 5.6 9.5 6.4 7.5 4.1 7.9 6.3 4.8 3.6 6.0 5.4 3.8 5.6 11.1 7.5 0.0 0.2 0.0 1.3 1.2 0.6 1.2 1.9 0.7 0.5 2.5 1.9 3.6 0.2 1.2 0.2 0.0 1.4 0.7 7.2 8.4 6.7 9.2 6.0 4.9 9.3 7.1 8.6 9.5 METAP2 "MAP2, MNPEP, p67" ENSG00000111142 "Methionyl aminopeptidase 2" P50579 12 95473520-95515839 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013025, HPA019095" Enhanced Supported "Plasma membrane,Cytosol" 22000 "Plasma membrane, Cytosol" "CAB013025: AB_2533993, HPA019095: AB_1853823" "unprognostic (1.91e-1)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.44e-1)" "unprognostic (3.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavourable (4.51e-6)" "unprognostic (1.25e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-2)" "unprognostic (8.53e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" 24.2 36.4 25.8 49.9 33.7 39.1 25.1 25.9 32.3 23.9 26.2 16.3 102.5 16.6 28.7 25.4 30.1 22.5 21.7 30.7 29.6 24.0 26.0 46.8 22.1 32.6 29.1 23.4 29.4 31.9 21.0 36.1 25.1 42.9 24.2 24.0 10.1 22.1 140.7 94.4 28.7 19.7 26.1 48.2 25.2 22.2 26.3 27.7 32.1 24.1 29.0 55.2 33.4 37.3 39.4 31.8 21.3 27.1 25.7 32.0 16.2 33.2 28.1 30.1 23.3 18.3 29.4 23.1 32.8 23.0 32.4 23.0 40.8 16.0 97.0 20.7 23.4 21.5 33.8 25.1 37.3 23.0 29.1 43.4 21.4 28.7 19.6 53.7 21.3 25.4 26.9 30.6 30.1 34.4 56.1 11.0 24.0 21.9 39.7 36.7 36.8 42.0 31.3 26.0 31.8 22.2 35.4 23.4 30.7 29.2 23.9 28.7 28.8 25.6 29.5 18.6 18.1 20.8 34.6 15.9 41.4 104.0 10.6 30.3 23.4 21.3 27.1 11.1 23.8 19.1 29.2 39.4 26.7 26.6 24.4 37.6 32.0 29.7 1.2 25.7 22.3 31.8 25.3 16.2 25.8 33.7 25.9 32.3 29.6 24.0 29.1 23.4 42.9 27.7 MGAM MGA ENSG00000257335 Maltase-glucoamylase O43451 7 141907813-142106747 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 155.5" "Cell line enhanced" "Detected in some" "A549: 3.6;BJ hTERT+: 3.2;HL-60: 5.3;U-937: 8.5;WM-115: 2.0" "Cancer enriched" "Detected in some" 7 "renal cancer: 4.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "neutrophil: 14.1" "Lineage enriched" "Detected in single" 104 "granulocytes: 14.1" "Region enriched" "Detected in single" 12 "olfactory region: 3.1" HPA002270 Enhanced 68000 "HPA002270: AB_1079366" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (6.95e-3)" "unprognostic (2.80e-1)" "unprognostic (7.81e-2)" "unprognostic (7.32e-3)" "unprognostic (3.83e-2)" "unprognostic (4.97e-1)" "unprognostic (2.17e-2)" "unprognostic (6.86e-2)" "unprognostic (1.99e-1)" "prognostic favourable (6.16e-5)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.34e-3)" "unprognostic (3.03e-1)" 0.9 0.2 0.3 0.8 0.2 6.9 0.3 0.2 0.2 0.2 59.4 0.1 7.6 25.2 0.2 36.0 0.2 1.0 0.1 0.3 0.2 0.2 8.7 0.4 2.1 0.1 0.3 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.6 0.0 0.1 0.2 3.2 0.2 0.1 155.5 0.1 0.3 8.3 0.7 4.3 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 14.1 0.1 0.0 0.0 0.0 0.0 3.6 0.2 0.1 0.0 0.0 0.4 0.1 3.2 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.3 1.0 0.4 0.1 0.3 0.0 0.1 0.0 8.5 2.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.1 0.1 MGAM2 ENSG00000257743 "Maltase-glucoamylase 2 (putative)" Q2M2H8 7 142111749-142222324 "Enzymes, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 61.2;pancreas: 15.6;salivary gland: 35.4" "Cell line enriched" "Detected in single" 7 "RH-30: 5.0" "Group enriched" "Detected in some" 11 "colorectal cancer: 3.5;pancreatic cancer: 2.5;stomach cancer: 9.8" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 12 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.1" "Low region specificity" "Detected in all" HPA055697 Enhanced Approved Vesicles,Cytosol Vesicles Cytosol "HPA055697: " "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-3)" "unprognostic (5.65e-2)" "unprognostic (2.19e-2)" "unprognostic (1.89e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-2)" "unprognostic (5.93e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-1)" "unprognostic (5.50e-4)" "unprognostic (7.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.71e-2)" "unprognostic (9.33e-2)" 0.2 0.1 0.1 2.5 0.1 0.2 1.3 0.1 0.1 0.1 28.8 0.0 0.0 15.0 0.1 0.4 0.1 0.3 7.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.4 0.0 0.1 15.6 0.0 0.1 0.0 0.1 0.1 1.4 0.7 35.4 0.0 0.1 0.2 61.2 0.0 0.5 1.5 0.7 1.0 0.0 0.0 0.1 1.7 0.8 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.1 0.0 MGEA5 "MEA5, NCOAT, OGA" ENSG00000198408 "Meningioma expressed antigen 5 (hyaluronidase)" O60502 10 101784443-101818465 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036141, HPA076501" Approved Supported Cytosol Cytosol "HPA036141: AB_10672079, HPA076501: " "unprognostic (4.34e-1)" "unprognostic (1.57e-1)" "prognostic unfavourable (8.69e-5)" "unprognostic (4.63e-1)" "unprognostic (2.06e-1)" "unprognostic (2.57e-2)" "unprognostic (2.65e-1)" "unprognostic (1.79e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-3)" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.01e-1)" "unprognostic (3.21e-2)" "unprognostic (1.90e-1)" "unprognostic (9.23e-3)" 29.5 17.5 51.9 27.4 54.4 49.3 35.5 58.9 51.4 24.5 27.0 29.0 20.9 17.6 29.9 36.8 26.0 23.3 19.1 27.4 46.0 29.8 27.7 28.6 24.0 40.1 30.7 43.6 33.8 20.9 53.3 22.1 25.5 42.6 31.6 26.5 30.7 24.4 26.3 25.4 36.6 28.5 37.4 29.5 35.2 23.9 21.9 35.4 32.9 25.9 11.8 39.5 34.3 26.7 8.1 3.3 14.7 5.6 6.8 7.1 1.4 30.6 15.6 22.9 44.3 14.7 35.7 15.9 21.6 21.9 10.1 17.4 11.5 19.7 20.5 15.8 25.7 22.1 21.3 27.2 21.5 30.0 14.6 20.5 21.8 8.9 15.9 15.1 11.6 34.5 30.6 17.3 41.3 18.7 14.4 38.1 17.1 15.6 15.9 15.8 12.6 15.8 22.2 25.2 15.0 16.9 27.8 9.9 17.6 19.3 10.5 27.0 27.6 16.5 28.3 15.6 15.1 22.5 24.7 19.1 30.3 16.4 19.6 26.0 8.5 10.5 2.1 6.8 7.1 2.0 5.6 6.4 4.9 6.1 1.3 8.1 6.8 5.7 14.7 6.8 5.6 3.3 4.5 1.4 51.9 54.4 58.9 51.4 46.0 29.8 30.7 43.6 42.6 35.4 MGLL "HU-K5, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-127823250 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 45.6;BJ hTERT+: 52.6;LHCN-M2: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 11.6;intermediate monocyte: 28.5;non-classical monocyte: 18.3;plasmacytoid DC: 30.4" "Group enriched" "Detected in many" 13 "dendritic cells: 30.4;granulocytes: 11.6;monocytes: 28.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm 4300000 Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavourable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" 72.2 6.7 29.4 22.6 29.7 7.5 39.0 32.8 36.9 13.3 36.3 8.3 8.4 16.5 8.7 10.8 63.8 16.3 24.1 35.5 23.6 10.2 22.6 32.1 32.4 6.0 15.4 17.8 3.9 3.6 1.7 5.0 18.9 10.2 10.6 27.6 10.0 31.4 13.6 40.9 11.9 22.3 13.6 12.2 19.2 17.5 3.2 15.5 2.4 6.4 33.4 19.7 14.4 14.5 1.8 30.4 11.6 28.5 0.6 0.9 6.0 11.0 9.9 0.0 0.0 17.4 20.6 1.3 45.6 52.6 10.1 16.3 0.3 4.5 2.8 12.7 15.4 0.4 0.0 6.0 5.6 4.9 0.1 0.3 7.1 0.0 6.3 0.0 0.3 7.7 3.5 18.9 20.7 21.4 0.0 0.5 42.0 1.1 0.0 0.1 0.0 15.8 0.0 5.4 23.4 37.9 1.2 5.8 0.4 7.8 15.5 2.7 0.7 0.4 27.4 11.1 3.3 26.7 6.2 0.0 0.0 9.3 23.0 0.6 34.3 4.2 2.8 11.6 0.2 28.5 0.9 1.8 0.2 0.3 3.1 0.2 0.0 0.0 0.5 0.6 18.3 30.4 0.0 6.0 29.4 29.7 32.8 36.9 23.6 10.2 15.4 17.8 10.2 15.5 MINDY1 "FAM63A, FLJ11280, MINDY-1" ENSG00000143409 "MINDY lysine 48 deubiquitinase 1" Q8N5J2 1 150996086-151008375 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 27.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 26.3;eosinophil: 19.1;neutrophil: 30.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028351, HPA028358, HPA061086" Approved Enhanced Nucleoplasm 240000 Nucleoplasm "HPA028351: AB_10611110, HPA028358: AB_10601102, HPA061086: " "unprognostic (5.73e-2)" "unprognostic (2.86e-1)" "unprognostic (5.47e-2)" "unprognostic (3.14e-1)" "unprognostic (3.39e-2)" "unprognostic (6.90e-2)" "unprognostic (1.47e-2)" "unprognostic (1.64e-1)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (9.22e-3)" "unprognostic (1.06e-1)" "prognostic favourable (3.43e-8)" "unprognostic (2.30e-1)" "unprognostic (7.95e-2)" "unprognostic (2.50e-2)" "unprognostic (6.06e-2)" 9.2 9.7 14.0 6.7 31.1 5.6 13.0 18.4 21.2 13.1 13.5 53.8 14.8 14.0 14.7 6.5 24.1 14.4 11.8 24.5 17.6 10.1 26.6 12.2 10.9 5.2 37.5 13.5 19.3 37.3 26.2 12.3 5.9 25.0 11.7 14.8 16.9 25.3 21.0 11.9 17.1 12.1 13.7 34.1 10.7 15.9 14.7 35.7 0.9 39.9 7.9 10.3 12.3 13.0 0.6 4.0 30.4 3.2 1.5 2.2 3.4 6.0 4.0 4.3 6.0 7.7 6.4 3.6 2.0 5.0 2.8 4.5 8.5 14.5 0.3 4.7 2.5 3.0 3.4 3.7 1.3 4.6 5.1 5.9 7.3 7.2 1.7 1.7 2.4 5.2 3.4 5.0 1.4 7.1 3.6 15.3 2.9 9.3 0.3 4.0 2.0 1.4 4.4 0.7 18.7 13.2 12.1 7.4 5.4 3.8 6.9 4.2 27.6 6.0 6.6 2.4 3.1 1.2 1.7 5.6 5.1 20.4 5.8 3.9 11.3 26.3 3.2 19.1 0.1 1.5 0.1 0.3 1.3 0.3 4.0 0.6 2.2 0.7 30.4 1.5 0.9 0.6 1.6 3.4 14.0 31.1 18.4 21.2 17.6 10.1 37.5 13.5 25.0 35.7 MINDY2 "FAM63B, KIAA1164" ENSG00000128923 "MINDY lysine 48 deubiquitinase 2" Q8NBR6 15 58771192-58861900 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051103, HPA063669" Approved Enhanced Nucleoplasm Nucleoplasm "HPA051103: , HPA063669: " "unprognostic (4.71e-2)" "unprognostic (8.92e-3)" "unprognostic (4.63e-2)" "unprognostic (4.13e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (8.60e-2)" "unprognostic (7.23e-2)" "unprognostic (7.09e-2)" "unprognostic (2.36e-3)" "unprognostic (4.74e-2)" "prognostic favourable (3.00e-8)" "unprognostic (2.53e-1)" "unprognostic (3.59e-1)" "unprognostic (6.76e-2)" "unprognostic (4.77e-2)" 14.0 9.2 15.5 8.8 14.7 5.6 11.1 41.0 15.4 12.4 8.8 12.4 11.8 5.8 13.0 8.0 11.8 11.7 10.4 16.7 14.6 12.6 16.9 5.8 12.5 6.1 16.2 15.5 11.7 6.4 15.5 12.5 21.9 14.9 15.0 6.6 11.7 7.7 11.8 6.1 11.4 6.5 13.6 16.9 9.4 7.8 6.2 15.8 8.6 15.8 5.4 6.0 13.1 9.1 4.6 2.9 5.5 3.1 1.9 5.5 1.4 5.7 2.8 4.0 2.4 6.1 11.2 6.4 5.3 11.3 1.6 2.4 4.5 2.9 2.9 5.8 6.3 5.6 7.3 4.3 2.6 3.0 2.6 4.1 3.1 4.0 3.7 3.1 3.8 4.9 7.2 1.9 4.5 4.0 7.1 3.3 3.9 0.7 3.8 2.3 8.6 1.5 1.7 11.6 3.1 4.9 6.5 3.7 2.7 3.8 5.4 9.6 1.6 6.6 4.7 2.3 2.1 39.9 2.3 3.0 4.2 2.9 5.2 5.1 5.6 5.5 1.8 3.3 3.2 1.6 5.5 2.7 2.8 3.5 0.6 4.6 2.4 3.3 3.9 1.9 3.1 2.9 2.2 1.4 15.5 14.7 41.0 15.4 14.6 12.6 16.2 15.5 14.9 15.8 MINDY3 "C10orf97, CARP, DERP5, FAM188A, FLJ13397, my042" ENSG00000148481 "MINDY lysine 48 deubiquitinase 3" Q9H8M7 10 15778170-15860520 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038400, HPA038406" Uncertain Supported "Nucleoplasm,Nuclear membrane" "Nucleoplasm, Nuclear membrane" "HPA038400: AB_10669724, HPA038406: " "unprognostic (9.20e-2)" "unprognostic (5.84e-2)" "unprognostic (3.09e-1)" "unprognostic (3.26e-1)" "unprognostic (1.99e-2)" "unprognostic (3.67e-1)" "unprognostic (8.29e-2)" "unprognostic (2.81e-2)" "unprognostic (3.85e-2)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (6.50e-2)" "unprognostic (1.32e-1)" "unprognostic (2.97e-1)" "unprognostic (1.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.19e-1)" 14.6 22.0 17.9 10.0 22.2 15.2 18.4 22.0 32.0 19.1 13.7 19.7 11.4 8.2 18.6 20.0 13.4 15.3 13.3 8.9 20.1 18.8 16.0 15.8 15.5 11.9 22.9 14.0 18.1 12.8 16.3 14.4 20.1 25.8 18.9 18.0 13.5 11.8 16.5 4.1 15.3 11.4 16.7 32.0 11.8 14.6 18.8 16.1 10.5 17.2 7.7 12.6 17.8 14.1 3.4 4.2 5.7 8.0 3.4 6.2 2.9 6.5 6.1 11.9 12.6 17.6 16.8 9.8 20.9 10.6 16.0 18.7 5.3 10.3 4.9 4.0 22.5 6.1 10.1 12.4 14.3 14.9 14.1 15.9 8.7 5.7 22.2 3.2 13.4 12.6 10.9 14.2 10.1 12.5 9.7 4.1 15.8 7.1 6.9 3.9 4.3 11.7 3.4 7.0 3.4 17.8 4.9 9.8 10.9 10.2 9.9 8.3 11.1 7.9 13.2 10.4 8.0 17.5 6.0 22.6 9.6 8.4 11.9 7.3 8.3 5.7 3.6 3.1 4.9 7.1 4.1 3.1 3.4 5.2 4.0 3.4 2.3 4.4 3.1 3.4 8.0 4.2 6.2 2.9 17.9 22.2 22.0 32.0 20.1 18.8 22.9 14.0 25.8 16.1 MINDY4 "C7orf67, FAM188B, FLJ22374" ENSG00000106125 "MINDY lysine 48 deubiquitinase 4" Q4G0A6 7 30771417-30892387 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 16.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "MAIT T-cell: 2.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.1;T-cells: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA019475, HPA030129, HPA030130" Approved Supported Vesicles,Cytosol "Vesicles, Cytosol" "HPA019475: AB_1848806, HPA030129: AB_10599621, HPA030130: AB_10601565" "unprognostic (2.96e-1)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.07e-1)" "unprognostic (6.01e-3)" "unprognostic (3.81e-2)" "unprognostic (5.25e-3)" "unprognostic (1.97e-1)" "unprognostic (5.59e-3)" "unprognostic (2.96e-2)" "unprognostic (1.92e-1)" "unprognostic (9.55e-2)" "unprognostic (1.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" 9.3 6.7 9.3 2.6 15.2 4.1 7.0 3.4 15.1 10.8 6.6 5.4 16.6 2.9 15.6 16.2 5.7 20.7 10.0 7.5 8.4 5.1 9.4 3.8 14.2 2.4 4.3 9.5 14.8 5.6 9.6 16.1 6.2 9.0 9.4 4.3 7.8 5.3 15.9 3.7 5.1 3.7 10.8 3.6 2.3 5.8 20.1 5.0 1.5 12.5 3.6 2.2 6.4 6.3 0.0 1.1 0.0 0.3 0.0 2.7 0.7 2.1 5.3 2.7 8.4 2.4 9.5 4.1 3.1 5.3 2.3 2.0 0.0 3.9 0.0 3.6 2.0 2.2 1.8 1.7 2.2 0.0 3.1 1.6 2.8 0.0 3.1 2.3 1.2 4.8 2.8 7.0 1.4 3.4 16.2 1.0 2.0 0.0 1.2 0.7 7.9 1.2 0.4 0.0 0.5 6.3 1.0 5.1 7.0 2.1 11.2 1.2 5.7 1.7 2.0 0.1 1.3 2.4 1.3 2.3 2.9 0.0 4.4 0.1 9.8 0.0 0.1 0.0 0.6 0.0 2.7 0.0 0.8 0.2 1.1 0.0 0.3 0.5 0.0 0.0 0.3 0.0 0.5 0.7 9.3 15.2 3.4 15.1 8.4 5.1 4.3 9.5 9.0 5.0 MINPP1 MIPP ENSG00000107789 "Multiple inositol-polyphosphate phosphatase 1" Q9UNW1 10 87504875-87553460 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026859 Approved "Intracellular and membrane" 320000000 "HPA026859: AB_1853961" "unprognostic (9.15e-2)" "unprognostic (8.76e-3)" "unprognostic (2.08e-2)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (5.20e-3)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (4.55e-1)" "unprognostic (2.07e-2)" "unprognostic (6.54e-2)" "unprognostic (6.50e-3)" "prognostic unfavourable (6.98e-5)" "unprognostic (2.43e-1)" "unprognostic (2.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.01e-2)" 9.9 27.6 8.5 8.0 8.9 24.6 14.2 12.0 9.2 9.1 13.3 8.0 12.8 16.7 12.1 10.0 5.4 8.4 9.5 7.2 8.5 10.0 19.4 28.9 9.5 10.1 8.2 6.3 11.1 18.2 10.2 18.5 31.4 7.6 11.6 12.4 9.3 8.9 12.2 5.9 9.5 19.4 7.4 8.2 8.2 8.9 8.8 8.5 13.5 13.1 5.3 6.5 8.7 13.9 8.9 13.5 8.5 12.9 10.4 16.4 9.3 8.3 12.9 12.9 18.9 22.0 18.2 10.9 13.6 23.3 13.5 18.1 6.8 16.4 7.2 12.7 16.0 13.0 13.6 12.4 15.4 16.5 16.2 18.5 5.2 25.2 16.5 7.9 16.9 15.9 16.0 15.0 9.1 16.9 10.8 35.3 15.6 6.2 5.2 11.2 9.3 9.3 0.0 7.4 4.9 17.7 4.7 4.7 14.8 12.9 2.7 22.6 7.8 6.6 14.8 8.7 10.5 10.3 13.0 11.5 11.8 1.9 13.9 12.2 6.3 8.5 10.3 4.6 11.6 12.9 10.3 8.9 11.0 13.2 13.5 7.3 10.6 11.9 0.7 10.4 10.8 7.8 16.4 9.3 8.5 8.9 12.0 9.2 8.5 10.0 8.2 6.3 7.6 8.5 MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889419 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favourable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" 7.3 14.9 6.2 7.1 12.2 4.4 11.0 4.7 10.3 8.1 12.2 12.9 12.1 8.4 9.6 20.4 14.4 17.1 11.7 16.9 8.8 5.3 24.7 12.0 8.2 8.4 5.1 8.0 8.5 14.7 8.1 15.4 5.3 9.1 10.9 13.1 9.1 12.9 10.1 16.2 22.0 8.9 11.5 4.4 6.5 9.8 13.9 4.9 8.9 10.9 15.7 11.1 11.2 8.6 9.2 6.5 1.2 10.6 9.7 10.0 3.9 8.9 10.1 5.0 11.7 11.5 15.5 10.7 6.5 10.1 9.8 8.2 13.4 17.8 10.5 6.6 5.2 22.6 11.5 13.6 12.2 6.1 7.3 4.6 4.8 11.5 9.4 10.7 2.5 7.6 17.1 10.1 9.0 12.2 8.8 1.7 15.2 6.6 7.6 6.0 6.9 10.2 8.5 13.5 9.1 21.8 6.0 11.8 3.9 6.9 11.4 13.6 11.7 6.0 6.7 6.0 5.0 9.8 6.9 1.7 2.4 5.6 10.3 5.5 7.4 0.0 3.0 1.2 7.9 3.7 10.0 9.2 7.7 7.1 6.5 7.7 7.4 7.3 0.0 9.7 10.6 5.6 5.1 3.9 6.2 12.2 4.7 10.3 8.8 5.3 5.1 8.0 9.1 4.9 MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183729 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 61.1;intestine: 136.0;kidney: 64.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 95.0;BJ hTERT+: 142.9;HSkMC: 92.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 129 "neutrophil: 61.1" "Lineage enriched" "Detected in single" 129 "granulocytes: 61.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 26.8" "CAB000013, HPA052583, HPA056072" Enhanced 99000 "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" 26.5 0.4 0.4 3.4 7.4 1.9 14.7 0.4 0.7 4.8 65.6 0.1 18.4 74.0 2.8 8.1 0.7 0.9 8.5 1.8 0.3 0.4 64.9 11.5 13.7 3.0 2.1 0.2 0.9 0.6 0.0 0.6 35.0 8.6 18.3 0.4 1.3 3.7 11.3 11.7 1.4 136.0 0.6 0.9 2.7 0.7 1.0 1.2 13.2 1.0 5.3 2.3 3.4 4.9 0.1 0.4 61.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 38.6 95.0 0.2 21.2 142.9 10.8 28.1 0.0 0.0 23.4 0.0 18.8 0.0 0.7 0.8 26.1 0.0 0.1 0.0 0.0 0.0 30.9 0.0 0.0 92.1 0.1 5.8 41.6 8.2 0.0 0.0 17.3 0.1 0.0 0.1 0.9 0.1 38.8 18.2 0.1 0.6 0.2 0.0 0.2 0.0 0.0 4.1 0.0 0.0 23.3 46.7 0.1 15.9 3.7 0.0 0.0 30.8 5.6 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 61.1 0.0 0.0 0.4 0.0 0.0 0.4 7.4 0.4 0.7 0.3 0.4 2.1 0.2 8.6 1.2 MMEL1 "MMEL2, NEPII, NL1, NL2, SEP" ENSG00000142606 "Membrane metalloendopeptidase like 1" Q495T6 1 2590639-2632990 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 30.2" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 17.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 8.5" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007876, HPA008205, CAB020786" Uncertain "Intracellular and membrane" "CAB020786: , HPA007876: AB_1854012, HPA008205: AB_1854011" "unprognostic (5.80e-2)" "unprognostic (4.61e-2)" "unprognostic (1.87e-1)" "unprognostic (4.27e-2)" "unprognostic (1.33e-1)" "unprognostic (2.71e-2)" "unprognostic (1.45e-1)" "unprognostic (7.96e-2)" "unprognostic (1.36e-2)" "unprognostic (2.37e-1)" "unprognostic (4.54e-3)" "unprognostic (2.44e-2)" "unprognostic (4.79e-2)" "unprognostic (3.18e-1)" "unprognostic (2.82e-1)" "unprognostic (2.18e-3)" "unprognostic (7.01e-4)" 1.5 0.5 0.8 1.8 8.5 0.6 1.8 0.4 0.6 4.3 4.2 0.4 1.9 3.2 0.8 10.3 3.0 3.0 9.6 1.3 1.0 2.6 1.4 0.4 1.4 1.4 1.7 0.4 1.1 7.3 0.3 0.4 0.7 0.5 4.2 1.4 0.4 2.0 2.0 0.4 0.3 2.6 0.9 0.7 1.4 7.9 30.2 0.9 0.8 1.1 0.8 0.8 3.7 1.6 0.6 1.1 6.6 5.1 2.3 6.1 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.9 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.5 0.0 17.4 0.0 1.6 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 1.5 6.6 0.5 3.9 0.3 0.6 1.7 0.7 1.1 0.0 4.5 2.2 1.0 2.3 5.1 0.2 6.1 2.2 0.8 8.5 0.4 0.6 1.0 2.6 1.7 0.4 0.5 0.9 MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789920-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 62.4;stomach 1: 27.2" "Cell line enhanced" "Detected in some" "BJ hTERT+: 88.1;HBF TERT88: 87.3;HUVEC TERT2: 229.4;WM-115: 113.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA004920 Approved Vesicles "Secreted to extracellular matrix" 430000 Vesicles "HPA004920: " "unprognostic (4.11e-3)" "prognostic unfavourable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavourable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavourable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" 0.2 0.1 0.3 12.3 0.3 0.0 0.9 0.3 0.3 0.3 2.7 0.3 0.2 3.2 4.8 0.2 3.3 0.1 62.4 0.4 0.2 0.1 0.7 1.3 4.7 0.2 0.2 0.2 0.2 1.6 0.0 0.2 8.6 0.5 0.7 3.0 0.3 2.0 0.2 0.2 0.3 8.8 0.2 0.4 1.8 27.2 2.2 0.2 0.4 0.3 1.3 0.9 11.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.9 88.1 36.0 9.4 0.7 0.0 0.0 0.4 21.1 0.3 0.0 12.3 87.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 37.0 3.1 229.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 11.9 29.9 0.0 1.3 0.1 0.0 0.0 0.0 0.7 0.0 113.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.3 0.3 0.3 0.3 0.2 0.1 0.2 0.2 0.5 0.2 MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770503-102780628 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "endometrium 1: 89.4" "Cell line enhanced" "Detected in some" "BJ: 12.3;HUVEC TERT2: 15.8;SCLC-21H: 5.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 102.2" "Region enriched" "Detected in single" 9 "pons and medulla: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (8.76e-2)" "unprognostic (3.38e-1)" "unprognostic (1.98e-3)" "unprognostic (2.72e-3)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (5.67e-8)" "unprognostic (2.08e-3)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (6.99e-5)" "unprognostic (2.66e-2)" "unprognostic (7.98e-2)" "unprognostic (5.46e-2)" "prognostic favourable (7.12e-4)" 0.1 0.1 0.0 2.6 0.2 0.1 0.1 0.0 0.3 1.7 0.5 0.0 0.0 0.4 89.4 0.1 0.2 0.1 0.5 0.1 0.0 0.1 0.1 3.6 11.0 0.1 0.0 0.0 0.5 0.3 0.1 0.9 19.8 2.8 3.2 0.2 0.0 2.9 0.1 0.1 0.1 0.7 0.1 0.0 0.2 3.3 0.5 0.0 1.2 0.1 0.0 1.9 0.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.2 12.3 0.7 0.1 0.1 0.3 0.0 0.0 3.6 1.9 2.8 0.0 1.4 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.6 15.8 0.7 0.0 0.0 0.0 0.0 0.3 2.9 1.7 0.0 0.0 0.0 0.0 0.7 5.0 0.0 2.5 0.0 0.0 0.0 0.0 2.0 3.8 1.2 0.4 0.5 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 2.8 0.0 MMP12 HME ENSG00000262406 "Matrix metallopeptidase 12" P39900 11 102862736-102875034 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 42.4;urinary bladder: 13.2" "Group enriched" "Detected in some" 12 "BJ: 4.1;fHDF/TERT166: 14.3;hTEC/SVTERT24-B: 8.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to extracellular matrix" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "prognostic unfavourable (1.42e-4)" "unprognostic (1.69e-2)" "unprognostic (7.31e-2)" "unprognostic (1.52e-2)" "unprognostic (1.52e-3)" "unprognostic (5.45e-2)" "unprognostic (3.05e-6)" "unprognostic (1.08e-2)" "unprognostic (4.66e-2)" "unprognostic (1.73e-1)" "unprognostic (6.92e-2)" 2.7 0.0 0.0 21.2 0.0 0.0 0.0 0.0 0.0 0.3 6.9 0.0 0.0 3.3 0.0 5.9 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.6 18.9 0.0 0.0 0.1 0.0 0.0 0.0 9.7 0.0 0.3 8.4 0.0 0.9 0.0 0.0 0.0 3.8 4.6 0.0 42.4 1.3 0.1 0.0 5.5 0.0 1.5 9.9 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 14.3 0.5 0.0 0.0 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.6 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836557-22849027 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 98.0;HHSteC: 92.7;HSkMC: 94.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" 570000 Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: " "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavourable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavourable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 60.9 10.5 2.4 16.6 4.7 0.2 64.2 2.2 3.2 56.3 35.0 8.2 12.7 12.0 53.1 24.1 47.0 21.9 39.6 17.5 3.4 1.8 16.8 9.0 29.8 16.9 5.8 2.9 39.3 11.2 34.4 4.7 73.5 16.4 39.1 11.3 27.1 24.4 16.7 20.4 37.0 22.9 28.5 20.7 22.5 18.2 26.3 4.6 5.4 22.3 14.6 16.7 52.5 53.9 0.1 0.7 0.0 0.7 0.0 0.0 0.1 7.9 0.1 2.4 0.1 98.0 62.3 45.0 25.1 50.6 7.6 13.6 2.3 29.9 0.1 14.0 26.4 20.3 0.0 26.1 9.8 0.1 0.1 3.7 0.1 0.5 92.7 0.0 0.1 94.2 15.8 31.7 27.2 46.0 0.1 0.2 17.9 0.1 0.0 9.0 1.5 4.3 0.3 8.6 0.0 6.9 13.7 0.0 0.0 16.4 0.0 54.4 0.1 8.1 40.7 61.9 5.3 18.0 28.6 0.1 0.1 0.1 37.7 0.0 35.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 4.7 2.2 3.2 3.4 1.8 5.8 2.9 16.4 4.6 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 335.4;ASC TERT1: 97.7;HSkMC: 83.3;U-138 MG: 91.2;U-87 MG: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" 160000000 Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 197.5 9.0 1.2 13.2 1.6 0.0 136.4 0.8 1.4 74.3 74.4 2.4 36.9 5.6 85.0 123.0 52.3 25.7 115.4 54.0 0.9 0.5 9.4 3.5 38.9 3.9 1.5 1.1 71.0 6.5 0.7 2.2 58.9 2.2 66.8 18.7 36.4 18.6 20.4 68.6 68.2 22.6 57.1 1.8 12.4 20.5 57.0 1.1 1.3 20.6 31.8 9.1 84.1 105.3 0.0 0.0 0.9 0.7 0.0 0.0 0.0 0.3 0.2 11.1 0.1 335.4 97.7 18.2 28.7 65.9 5.8 4.6 0.0 0.1 0.0 23.1 50.5 3.1 0.0 0.2 3.3 0.0 0.0 0.0 0.7 0.1 31.7 0.0 0.8 83.3 0.0 29.8 0.2 37.4 0.0 0.1 19.3 0.0 0.0 0.4 8.8 0.0 0.0 2.6 0.0 0.9 0.4 0.1 20.2 5.3 0.0 0.1 0.0 2.0 52.7 91.2 8.7 17.5 3.7 0.0 0.0 0.1 106.8 1.5 16.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 1.2 1.6 0.8 1.4 0.9 0.5 1.5 1.1 2.2 1.1 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843803 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 177.5;salivary gland: 73.4" "Group enriched" "Detected in some" 17 "BJ: 98.9;BJ hTERT+: 269.1;fHDF/TERT166: 116.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" 170000 Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavourable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavourable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 19.1 0.0 0.2 14.4 0.3 0.0 6.9 0.2 0.5 0.2 1.5 0.3 0.2 1.8 28.3 177.5 0.2 0.0 1.4 0.2 0.2 0.0 0.3 0.5 0.4 0.2 0.2 0.2 0.3 0.2 0.0 0.2 0.2 0.2 1.2 1.7 0.2 73.4 1.5 7.3 12.6 0.7 5.9 0.2 0.2 2.8 1.4 0.2 0.2 0.6 1.5 0.9 7.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.9 269.1 1.7 0.5 0.0 0.0 0.0 0.0 116.5 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 7.9 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.2 0.8 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.5 0.2 0.0 0.2 0.2 0.2 0.2 MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530753 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 93.0;kidney: 129.5;salivary gland: 79.3" "Cell line enhanced" "Detected in some" "A549: 22.6;CAPAN-2: 126.5;EFO-21: 30.0;RPTEC TERT1: 54.7" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Region enriched" "Detected in single" 5 "pons and medulla: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: " "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavourable (2.53e-4)" "prognostic unfavourable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" 6.8 0.2 0.2 1.2 0.2 0.0 28.8 0.2 0.2 5.2 0.2 0.2 2.1 0.0 17.2 12.3 3.3 16.4 93.0 0.2 0.2 0.2 129.5 1.4 5.0 0.9 0.2 0.2 3.9 23.5 0.0 0.7 2.7 1.3 42.0 0.0 0.2 79.3 6.7 0.2 7.8 0.3 0.5 0.2 0.2 0.9 9.4 0.2 1.2 0.3 1.4 4.5 19.9 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 126.5 0.0 30.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 1.3 0.2 MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711795-102727050 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "bone marrow: 119.3" "Cell line enriched" "Detected in some" 8 "WM-115: 39.2" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Region enhanced" "Detected in single" "cerebral cortex: 1.7" "Group enriched" "Detected in some" 32 "neutrophil: 1.4;non-classical monocyte: 4.9" "Group enriched" "Detected in many" 32 "granulocytes: 1.4;monocytes: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA022935" Enhanced "Secreted to extracellular matrix" 83000 "HPA021221: AB_1854043, HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" 1.9 0.1 0.2 0.2 0.4 119.3 0.3 0.1 1.7 0.1 0.2 0.0 0.0 0.1 0.6 0.1 0.1 0.1 0.1 9.0 0.2 0.3 0.4 0.8 12.6 2.6 0.3 0.0 0.9 0.9 0.1 0.6 1.4 0.2 0.1 0.1 0.1 0.3 0.1 0.6 0.3 0.1 0.2 0.3 18.7 0.2 0.1 0.1 5.2 1.9 0.0 0.1 0.2 7.6 0.0 0.0 1.4 4.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.9 0.0 0.0 1.7 0.2 0.4 0.1 1.7 0.2 0.3 0.3 0.0 0.2 0.1 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 64.0;blood: 63.2;bone marrow: 89.4;lymphoid tissue: 80.1" "Cell line enriched" "Detected in some" 12 "NB-4: 87.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 141 "neutrophil: 63.2" "Lineage enriched" "Detected in single" 339 "granulocytes: 63.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" 57000000 Cytosol "CAB000348: , CAB068199: , CAB068200: , CAB068201: , HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favourable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavourable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavourable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 64.0 0.5 0.6 38.6 0.7 89.4 4.3 0.4 0.6 0.8 1.2 0.1 0.0 2.8 0.6 0.2 0.9 1.5 0.6 4.0 0.5 0.6 1.4 2.0 13.3 80.1 0.6 0.0 2.7 1.4 0.0 0.8 2.6 0.5 0.6 0.8 0.5 12.5 0.0 1.3 1.3 4.2 0.3 0.5 53.7 2.5 2.7 0.0 23.6 1.3 2.3 44.5 4.5 2.9 0.0 0.0 63.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 7.3 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 87.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 2.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.4 0.6 0.5 0.6 0.6 0.0 0.5 0.0 MOGS "CWH41, DER7, GCS1" ENSG00000115275 "Mannosyl-oligosaccharide glucosidase" Q13724 2 74461057-74465410 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011322, HPA011969" Approved Supported "Endoplasmic reticulum" 88000000 "Endoplasmic reticulum" "HPA011322: , HPA011969: AB_1849579" "unprognostic (5.66e-2)" "unprognostic (1.98e-2)" "prognostic unfavourable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-1)" "prognostic unfavourable (2.34e-6)" "unprognostic (1.48e-2)" "unprognostic (2.66e-2)" "unprognostic (3.32e-2)" "unprognostic (6.21e-2)" "unprognostic (4.36e-1)" "prognostic unfavourable (2.79e-8)" "unprognostic (1.40e-2)" "unprognostic (3.06e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" 15.8 12.8 8.7 15.2 10.6 8.5 13.1 11.3 12.1 13.9 19.4 10.8 24.9 36.5 14.2 15.8 15.5 13.4 16.4 11.2 7.7 6.1 14.8 40.5 17.2 15.6 9.2 7.9 14.2 30.6 20.4 15.7 35.8 8.3 15.9 11.2 11.7 24.5 25.3 14.1 17.4 35.8 9.8 7.1 22.4 22.3 11.9 8.1 17.6 18.9 11.4 19.5 14.1 12.9 3.9 3.4 2.3 4.4 12.7 5.1 2.5 22.1 19.7 13.1 12.6 27.0 19.1 40.1 18.2 26.3 27.6 26.6 36.0 23.7 24.0 16.2 18.3 22.3 19.7 20.5 17.1 20.7 19.1 11.2 12.8 27.6 22.3 26.3 22.6 11.1 32.9 19.5 19.1 30.9 19.5 23.3 12.1 27.6 14.2 20.2 17.3 11.0 16.3 29.1 31.1 15.0 13.8 10.8 14.1 8.6 36.1 23.6 17.5 14.2 22.0 12.7 22.2 18.4 24.0 36.0 14.8 10.6 20.0 21.5 17.2 2.3 4.0 1.1 5.0 2.5 5.1 2.5 4.2 4.5 3.4 3.9 3.7 2.4 0.7 12.7 4.4 3.2 3.8 2.5 8.7 10.6 11.3 12.1 7.7 6.1 9.2 7.9 8.3 8.1 MOV10 "fSAP113, gb110, MGC2948" ENSG00000155363 "Mov10 RISC complex RNA helicase" Q9HCE1 1 112673141-112700746 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031627 Approved Cytosol Cytosol "HPA031627: " "unprognostic (1.44e-2)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" "unprognostic (6.82e-3)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "prognostic unfavourable (3.44e-4)" "unprognostic (9.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.58e-3)" "unprognostic (2.85e-1)" "unprognostic (1.54e-1)" "prognostic unfavourable (1.48e-11)" "unprognostic (4.01e-2)" "unprognostic (3.61e-1)" "unprognostic (1.46e-3)" "unprognostic (1.21e-3)" 12.5 17.0 6.2 12.6 6.9 3.5 15.0 1.9 6.3 11.4 23.1 9.3 12.3 18.8 16.4 12.6 15.8 12.2 15.3 5.8 8.6 5.1 13.3 19.4 9.7 7.7 5.9 5.1 14.5 12.9 13.1 14.1 20.2 8.2 14.0 9.3 13.8 13.5 16.5 3.1 23.2 33.8 9.4 6.3 12.9 10.4 17.7 6.0 14.5 12.1 6.9 10.9 11.0 12.5 1.9 5.6 0.9 9.5 9.9 10.8 5.9 11.8 7.3 4.4 16.8 3.5 10.2 16.5 8.1 19.4 24.1 34.5 13.5 13.1 0.0 5.6 11.2 12.6 16.5 19.6 8.4 13.0 10.0 8.2 10.6 15.2 15.3 3.4 8.1 17.2 6.0 14.6 4.6 20.4 10.8 4.1 7.4 22.0 12.9 2.6 9.8 7.5 23.3 11.0 0.5 11.1 13.0 1.8 6.3 16.9 11.4 13.2 8.9 7.8 12.2 7.5 13.5 5.2 7.2 4.7 1.3 0.0 14.8 7.1 21.4 0.7 2.8 0.5 10.7 8.4 10.8 1.9 9.7 9.7 5.6 1.4 9.4 7.1 0.9 9.9 9.5 0.9 8.2 5.9 6.2 6.9 1.9 6.3 8.6 5.1 5.9 5.1 8.2 6.0 MOV10L1 "CHAMP, DJ402G11.8, DKFZp434B0717" ENSG00000073146 "Mov10 RISC complex RNA helicase like 1" Q9BXT6 22 50089879-50161690 "Enzymes, Predicted intracellular proteins" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 27.7" "Cell line enhanced" "Detected in some" "HHSteC: 3.2;HUVEC TERT2: 15.7;TIME: 7.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019034 Approved "HPA019034: AB_1854070" "unprognostic (1.39e-1)" "unprognostic (2.30e-2)" "unprognostic (1.88e-2)" "unprognostic (7.91e-2)" "unprognostic (4.29e-2)" "unprognostic (4.05e-2)" "unprognostic (1.21e-1)" "unprognostic (2.69e-1)" "unprognostic (9.43e-2)" "unprognostic (7.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.03e-1)" "unprognostic (8.02e-3)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" 0.4 0.1 0.7 0.2 1.5 0.3 0.2 1.3 1.3 0.9 0.8 0.6 0.2 0.1 3.0 2.0 0.4 1.0 1.2 0.3 0.9 0.6 0.3 1.0 0.3 0.2 0.5 1.5 1.8 0.2 0.1 0.4 0.6 2.1 1.0 0.2 0.6 0.2 0.2 0.2 0.3 0.4 1.9 0.7 0.2 0.1 27.7 0.2 0.2 0.5 0.2 0.3 0.4 2.0 0.0 0.0 0.0 0.6 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.5 1.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 3.2 0.0 1.5 0.2 0.0 0.0 0.0 15.7 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 7.2 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 1.5 1.3 1.3 0.9 0.6 0.5 1.5 2.1 0.2 MPG MDG ENSG00000103152 "N-methylpurine DNA glycosylase" P29372 16 77007-85853 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006531 Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA006531: AB_1854075" "unprognostic (1.78e-2)" "unprognostic (8.48e-2)" "unprognostic (9.99e-2)" "prognostic favourable (2.82e-5)" "unprognostic (8.54e-2)" "unprognostic (3.27e-1)" "unprognostic (2.75e-2)" "unprognostic (1.63e-1)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (1.85e-2)" "unprognostic (1.83e-2)" "unprognostic (1.39e-2)" "unprognostic (1.86e-3)" "unprognostic (3.88e-2)" "unprognostic (1.86e-2)" "unprognostic (3.26e-1)" 20.8 32.1 18.4 21.1 18.4 25.3 33.2 18.3 32.1 19.5 20.4 12.6 24.6 21.0 22.6 30.5 21.5 18.5 28.5 37.4 16.7 15.1 16.1 32.0 20.1 39.7 15.8 18.2 23.8 36.5 8.0 21.7 19.0 16.5 23.2 7.2 15.2 47.1 24.2 33.6 19.0 19.4 19.2 13.6 25.6 27.3 10.9 11.2 18.3 29.2 22.4 22.8 27.2 25.2 33.5 38.8 27.2 27.4 41.2 31.1 22.4 13.8 20.3 5.5 17.0 10.2 23.3 13.9 20.0 27.6 13.0 14.3 12.8 18.8 9.9 17.5 11.3 17.9 3.8 8.7 2.0 17.0 14.7 6.4 10.4 19.0 29.5 6.7 39.8 22.4 12.2 14.6 6.0 22.6 14.1 17.9 16.9 48.0 11.6 30.9 10.0 22.2 22.2 6.7 37.7 10.8 5.0 4.5 11.6 10.5 11.4 25.1 16.3 34.7 19.8 10.6 13.5 14.4 9.8 17.4 5.9 12.6 19.6 19.4 37.8 14.2 27.4 27.2 22.7 19.2 20.6 33.5 21.8 22.6 28.5 30.6 16.8 17.2 14.0 41.2 15.7 38.8 31.1 22.4 18.4 18.4 18.3 32.1 16.7 15.1 15.8 18.2 16.5 11.2 MRPL58 "DS-1, ICT1" ENSG00000167862 "Mitochondrial ribosomal protein L58" Q14197 17 75012670-75021261 "Enzymes, Predicted intracellular proteins, Ribosomal proteins" "Protein biosynthesis" "Hydrolase, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003634 Approved Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA003634: AB_1851388" "unprognostic (2.04e-1)" "unprognostic (1.57e-2)" "unprognostic (1.94e-3)" "unprognostic (7.12e-2)" "unprognostic (3.16e-2)" "unprognostic (4.35e-2)" "unprognostic (1.38e-3)" "unprognostic (1.52e-1)" "unprognostic (2.57e-1)" "unprognostic (3.79e-3)" "unprognostic (4.98e-2)" "unprognostic (2.43e-2)" "prognostic unfavourable (2.09e-4)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.66e-2)" "unprognostic (1.71e-1)" 12.4 23.4 13.9 18.4 14.8 13.7 17.6 18.1 15.7 10.6 15.2 9.8 17.5 13.1 12.5 15.1 19.4 12.5 16.3 31.2 12.2 12.0 25.7 41.7 10.2 15.2 14.3 14.0 10.5 24.2 13.5 9.1 13.9 14.0 13.6 16.3 10.1 17.7 22.5 57.3 16.5 13.4 14.8 12.9 14.6 15.1 7.6 14.0 13.2 14.8 31.2 15.7 14.3 11.6 18.3 28.9 11.2 22.0 20.0 33.5 20.9 26.2 37.1 12.4 14.2 13.3 13.2 17.3 15.6 17.0 32.5 27.7 28.4 16.5 18.3 12.8 15.4 18.8 25.3 26.8 34.4 9.3 30.0 14.3 17.5 23.6 25.2 29.9 9.9 14.3 12.8 21.6 34.6 24.7 23.1 13.4 18.3 32.8 25.8 20.6 9.3 50.3 13.4 22.0 26.6 23.9 19.5 11.5 22.1 13.5 24.7 30.2 32.9 24.8 10.4 17.6 19.3 18.4 29.3 14.0 11.1 20.2 20.1 33.6 14.5 11.2 22.0 10.5 17.3 20.7 14.9 18.3 21.1 17.2 28.9 14.8 15.7 17.6 2.0 20.0 17.4 19.4 33.5 20.9 13.9 14.8 18.1 15.7 12.2 12.0 14.3 14.0 14.0 14.0 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" P11586 14 64388031-64463457 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis" "Hydrolase, Ligase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 121.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol 250000 Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: " "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavourable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favourable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 18.9 9.0 8.1 8.4 18.1 9.7 12.2 5.7 15.9 7.1 9.3 9.0 4.0 7.5 8.5 6.9 12.0 6.7 6.4 10.6 8.4 6.5 20.5 121.6 6.8 9.2 8.0 10.4 10.1 13.4 13.1 5.6 5.6 10.0 5.5 11.4 9.3 11.6 5.6 26.5 7.6 7.3 8.8 6.9 8.3 7.9 2.3 7.4 15.6 8.6 14.0 12.5 8.7 7.3 21.1 12.8 0.5 13.2 12.8 14.9 8.4 72.1 41.1 15.6 34.0 16.8 13.7 25.3 28.3 19.5 36.8 36.5 39.9 33.3 30.4 13.4 16.8 35.5 48.2 28.2 43.1 30.1 31.7 37.6 41.2 30.2 12.4 28.8 20.5 10.7 9.1 32.8 17.8 22.9 28.0 25.0 27.8 59.9 46.4 16.9 28.6 43.6 37.1 54.3 27.5 27.6 42.3 33.8 13.1 47.4 25.8 14.2 40.1 14.6 14.1 27.8 48.1 25.5 33.9 16.7 20.5 53.5 25.4 33.4 31.4 0.2 8.2 0.1 8.1 13.2 10.9 21.1 9.0 9.9 12.8 11.6 7.6 10.1 0.5 12.8 10.3 3.2 14.9 8.4 8.1 18.1 5.7 15.9 8.4 6.5 8.0 10.4 10.0 7.4 MTHFD2 ENSG00000065911 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" P13995 2 74198562-74217565 "Enzymes, Predicted intracellular proteins" "One-carbon metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003684, HPA049657" Approved "Intracellular and membrane" "CAB003684: AB_425867, HPA049657: " "unprognostic (1.82e-3)" "unprognostic (4.60e-2)" "unprognostic (8.12e-2)" "prognostic unfavourable (2.07e-5)" "prognostic favourable (1.01e-4)" "unprognostic (3.10e-3)" "unprognostic (2.24e-3)" "unprognostic (4.75e-3)" "unprognostic (2.64e-2)" "unprognostic (3.96e-2)" "unprognostic (3.76e-3)" "unprognostic (3.57e-3)" "prognostic unfavourable (1.11e-16)" "unprognostic (3.66e-2)" "unprognostic (6.52e-2)" "unprognostic (9.07e-2)" "unprognostic (2.34e-3)" 26.2 5.7 5.8 21.6 14.1 12.1 21.9 3.0 8.0 15.1 12.4 5.9 12.6 10.1 15.8 8.7 14.1 17.5 10.5 12.1 10.0 8.2 12.0 3.4 15.9 21.0 19.0 1.5 20.6 39.7 1.5 15.6 8.2 16.1 12.7 15.3 3.0 32.9 12.0 39.4 8.6 9.2 21.0 25.6 26.3 15.3 11.9 11.8 8.4 11.4 16.7 23.5 20.3 41.8 4.8 11.4 13.6 19.7 10.7 12.7 6.3 18.9 7.0 8.0 27.0 8.8 9.9 21.0 23.9 16.2 14.1 20.0 16.2 8.0 40.1 6.4 13.0 6.7 26.4 14.0 26.6 21.6 11.0 38.7 3.9 15.7 35.8 28.1 25.9 20.4 44.9 17.5 76.1 9.4 17.8 58.4 13.8 11.9 17.6 34.8 17.3 11.7 19.6 22.3 35.3 8.0 5.6 20.7 15.2 8.2 24.9 56.0 21.3 39.1 4.1 4.4 35.3 10.0 26.8 48.4 21.4 32.6 12.2 34.5 12.4 13.6 8.1 9.6 3.3 19.7 4.8 4.8 6.0 3.6 11.4 3.0 4.3 3.3 1.1 10.7 19.1 5.0 12.7 6.3 5.8 14.1 3.0 8.0 10.0 8.2 19.0 1.5 16.1 11.8 MTHFD2L MGC72244 ENSG00000163738 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like" Q9H903 4 74114174-74303099 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035434 Uncertain "HPA035434: AB_10601038" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "unprognostic (2.03e-1)" "unprognostic (2.32e-2)" "unprognostic (1.52e-2)" "unprognostic (4.09e-2)" "unprognostic (2.67e-2)" "unprognostic (7.73e-3)" "unprognostic (1.42e-4)" "unprognostic (3.45e-3)" "unprognostic (4.23e-2)" "unprognostic (5.07e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (1.19e-1)" "unprognostic (3.00e-1)" "unprognostic (1.81e-3)" 5.4 11.7 10.2 6.0 8.8 5.2 10.3 6.9 8.5 4.5 5.6 5.9 8.2 5.3 5.6 10.9 6.3 5.0 5.6 17.7 9.3 10.7 6.9 16.2 7.0 5.8 10.5 4.1 5.8 13.6 6.1 7.4 5.8 6.6 5.3 4.0 4.8 4.9 6.2 9.3 4.2 5.6 4.9 11.0 5.1 4.1 2.9 7.3 14.8 10.5 5.0 3.8 3.8 8.4 3.9 3.9 1.4 6.5 2.5 2.7 2.5 2.6 2.7 3.9 3.5 1.4 2.1 0.9 3.2 2.5 2.2 2.4 2.0 2.5 2.9 4.4 1.4 1.6 3.1 2.1 3.2 2.9 1.9 3.5 1.8 2.5 2.4 5.4 0.7 1.5 5.0 3.2 7.8 4.6 6.0 3.5 2.6 2.5 10.0 7.7 1.1 3.0 10.2 2.6 4.7 13.9 1.3 3.6 7.9 1.8 2.7 3.3 1.5 3.8 4.6 2.5 3.8 4.7 5.3 3.6 4.6 8.3 15.3 1.3 3.7 0.4 2.1 0.9 0.7 2.0 0.7 3.9 0.6 0.9 3.3 1.5 2.1 2.2 1.4 2.5 6.5 3.9 2.7 2.5 10.2 8.8 6.9 7.3 9.3 10.7 10.5 4.1 6.6 7.3 MTM1 ENSG00000171100 "Myotubularin 1" Q13496 X 150568619-150673322 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010008, HPA010665" Approved Supported "Plasma membrane" "Plasma membrane" "HPA010008: AB_1079426, HPA010665: AB_1079425" "unprognostic (3.66e-3)" "unprognostic (8.43e-3)" "unprognostic (3.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (6.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.74e-1)" "unprognostic (2.35e-2)" "unprognostic (1.08e-1)" "unprognostic (4.59e-2)" "prognostic favourable (7.40e-7)" "unprognostic (4.46e-2)" "unprognostic (1.25e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" 10.7 17.9 15.0 10.2 16.4 11.1 9.2 10.6 10.8 9.1 21.5 12.5 12.7 12.8 10.9 10.9 11.1 11.1 8.0 9.0 14.3 12.0 17.9 19.9 12.2 12.4 17.3 9.3 13.8 7.5 21.4 11.9 21.5 12.9 9.5 21.6 8.3 10.2 12.9 11.2 10.2 21.0 8.0 17.2 15.3 8.6 12.1 16.4 14.5 12.7 8.3 13.9 8.5 9.1 6.9 7.9 18.4 7.2 10.1 7.7 4.6 8.5 3.9 5.5 2.0 5.0 5.0 3.5 4.1 5.6 4.7 5.2 3.0 4.7 13.8 7.3 5.2 6.1 4.0 7.9 5.8 3.7 3.5 3.7 3.7 9.1 3.8 15.3 12.5 3.0 9.5 3.8 8.1 6.1 2.3 12.8 5.7 2.8 4.2 15.8 2.8 5.1 5.1 3.1 2.7 8.1 4.8 1.4 1.5 3.5 7.4 5.2 2.6 22.3 5.3 3.1 1.9 8.1 4.2 2.6 5.9 13.1 4.0 9.4 5.1 17.6 6.3 18.4 1.5 7.2 4.9 5.5 6.8 5.2 7.9 6.9 6.5 3.9 8.5 10.1 6.2 5.1 7.7 4.6 15.0 16.4 10.6 10.8 14.3 12.0 17.3 9.3 12.9 16.4 MTMR1 ENSG00000063601 "Myotubularin related protein 1" Q13613 X 150692971-150765103 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002977, HPA018502" Approved Approved Centrosome Centrosome "HPA002977: , HPA018502: AB_1854185" "unprognostic (2.37e-2)" "unprognostic (1.64e-3)" "unprognostic (2.07e-1)" "unprognostic (1.05e-2)" "unprognostic (4.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (4.35e-2)" "unprognostic (3.16e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-2)" "unprognostic (1.67e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.19e-1)" "unprognostic (8.40e-2)" 6.9 6.8 20.4 14.0 17.9 9.9 11.8 14.5 15.6 8.3 8.6 8.7 7.2 8.3 9.4 9.2 19.7 9.3 9.0 12.0 17.8 13.4 8.1 10.2 9.7 18.7 12.1 11.5 7.4 11.7 16.3 10.2 37.9 8.8 10.8 9.1 7.9 12.1 13.0 22.2 19.8 10.9 8.3 8.2 18.0 9.7 11.0 9.3 32.6 9.6 10.7 23.1 10.4 7.7 3.3 7.8 7.4 1.5 6.2 4.8 1.8 12.9 8.3 9.0 7.3 2.1 2.4 12.1 11.5 14.9 11.8 16.7 8.0 10.3 28.4 17.1 9.3 11.8 18.1 16.8 18.4 11.5 10.9 1.8 13.0 3.4 6.2 8.3 6.2 6.7 11.7 12.9 0.2 7.1 5.4 7.3 8.4 11.1 12.1 2.1 4.1 12.6 6.5 14.3 12.5 9.2 14.9 13.4 8.4 4.4 9.9 3.7 12.6 4.7 8.9 7.8 6.2 1.0 17.1 9.4 9.6 43.2 1.5 5.4 5.9 0.0 0.9 7.4 3.5 1.5 2.6 2.7 3.9 3.2 2.2 3.3 3.5 4.7 2.4 6.2 1.3 7.8 4.8 1.8 20.4 17.9 14.5 15.6 17.8 13.4 12.1 11.5 8.8 9.3 MTMR2 "CMT4B, KIAA1073" ENSG00000087053 "Myotubularin related protein 2" Q13614 11 95832882-95925315 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049831 Approved Supported Vesicles Vesicles "HPA049831: " "unprognostic (1.71e-2)" "unprognostic (2.55e-3)" "unprognostic (7.81e-3)" "unprognostic (4.16e-1)" "unprognostic (4.18e-3)" "unprognostic (5.36e-2)" "prognostic unfavourable (1.61e-8)" "unprognostic (3.23e-3)" "unprognostic (3.42e-2)" "unprognostic (1.77e-2)" "prognostic unfavourable (3.60e-4)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (8.03e-3)" 16.4 10.4 14.2 12.1 19.9 5.3 15.4 14.9 23.3 14.1 13.5 22.6 4.9 8.0 14.1 7.5 15.5 13.3 15.4 13.8 18.1 13.9 16.9 4.5 14.3 13.6 27.5 13.6 14.5 11.0 15.9 8.2 25.1 21.3 17.6 14.5 19.6 18.8 12.3 6.8 9.7 9.5 18.2 30.0 10.5 13.6 29.0 21.8 12.2 11.3 7.7 11.7 13.4 14.3 5.4 6.6 9.7 4.9 11.8 14.2 6.6 9.2 9.9 22.9 16.5 8.0 12.5 19.1 17.3 15.5 17.3 15.6 23.4 18.8 6.6 20.8 18.3 12.9 18.6 18.9 15.5 12.2 9.0 13.9 24.8 13.1 18.4 23.4 11.4 10.4 12.6 22.6 22.7 25.9 17.1 6.4 16.1 6.9 11.6 10.9 18.6 14.1 9.8 13.4 6.3 17.7 49.8 14.6 17.1 17.1 14.5 7.7 11.5 10.0 26.5 20.1 18.5 14.7 15.9 6.0 16.5 6.1 8.5 6.5 20.4 9.7 3.3 1.4 11.4 3.9 12.3 5.4 7.7 14.2 6.6 4.8 4.1 11.0 0.9 11.8 4.9 3.4 6.9 6.6 14.2 19.9 14.9 23.3 18.1 13.9 27.5 13.6 21.3 21.8 MTMR3 "FYVE-DSP1, KIAA0371, ZFYVE10" ENSG00000100330 "Myotubularin related protein 3" Q13615 22 29883155-30030866 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034515, HPA034516, HPA061399" Uncertain Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA034515: AB_10669726, HPA034516: AB_10669727, HPA061399: " "unprognostic (4.39e-3)" "unprognostic (7.84e-2)" "unprognostic (2.46e-2)" "unprognostic (1.76e-2)" "unprognostic (5.61e-2)" "unprognostic (4.51e-3)" "unprognostic (2.25e-2)" "unprognostic (3.20e-2)" "unprognostic (3.42e-1)" "unprognostic (4.39e-1)" "unprognostic (8.33e-4)" "unprognostic (1.28e-1)" "unprognostic (5.35e-4)" "unprognostic (7.96e-2)" "unprognostic (7.64e-2)" "unprognostic (2.49e-1)" "unprognostic (8.38e-2)" 15.8 17.2 15.7 12.6 20.6 66.7 16.0 24.2 18.0 13.7 12.6 18.9 14.8 10.6 18.8 13.5 20.1 16.7 13.0 14.4 13.0 11.7 12.4 9.9 18.3 12.6 14.7 11.4 20.3 15.8 22.1 20.6 20.6 15.8 15.1 12.9 18.1 15.9 14.7 30.7 22.5 13.1 16.0 17.0 20.7 14.1 23.7 14.6 14.0 16.6 11.9 14.9 14.0 19.3 2.6 3.9 16.5 6.6 3.9 4.1 3.5 8.4 6.6 11.4 12.1 11.5 8.4 8.4 7.5 11.4 10.3 11.9 6.1 5.1 6.4 5.0 14.4 10.4 12.0 9.5 10.4 12.7 10.0 11.6 6.6 6.6 10.6 9.8 29.5 8.9 15.8 10.0 18.2 10.2 7.1 11.5 6.3 10.5 6.6 7.2 4.2 4.9 7.8 15.5 6.5 9.7 15.7 12.7 8.7 14.3 13.0 7.7 7.3 9.9 10.9 16.9 11.4 3.4 5.3 10.0 6.7 6.0 7.3 4.9 7.7 6.4 6.6 10.0 3.1 4.6 4.1 2.2 2.5 3.4 3.9 2.6 3.1 2.7 16.5 3.9 4.7 1.5 2.7 3.5 15.7 20.6 24.2 18.0 13.0 11.7 14.7 11.4 15.8 14.6 MTMR4 "KIAA0647, ZFYVE11" ENSG00000108389 "Myotubularin related protein 4" Q9NYA4 17 58489529-58517905 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (3.07e-1)" "unprognostic (6.52e-2)" "unprognostic (4.87e-3)" "unprognostic (1.68e-2)" "unprognostic (1.54e-1)" "unprognostic (6.42e-2)" "unprognostic (4.97e-2)" "unprognostic (3.45e-3)" "unprognostic (6.82e-2)" "unprognostic (2.21e-1)" "prognostic favourable (5.09e-4)" "unprognostic (1.04e-1)" "prognostic unfavourable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (2.13e-1)" "unprognostic (1.59e-2)" "unprognostic (2.92e-2)" 8.7 9.9 16.6 10.3 18.7 14.4 11.6 32.7 22.7 8.3 11.4 18.3 6.7 17.7 10.3 16.2 9.5 10.1 6.7 8.3 15.8 14.4 14.6 32.0 8.0 13.4 16.5 15.4 13.3 10.4 16.2 11.2 29.8 36.9 10.9 14.8 11.1 8.7 9.1 6.1 11.8 17.3 9.4 10.9 13.3 9.4 15.2 17.3 15.5 13.9 3.4 18.2 9.7 8.2 8.4 6.3 9.9 7.9 3.3 5.8 3.8 9.4 10.3 15.7 15.2 9.7 9.9 12.2 5.7 9.8 15.1 14.0 10.0 6.2 19.7 8.1 5.9 5.6 16.9 9.8 16.3 20.3 11.7 13.4 8.2 13.2 10.9 14.0 12.3 10.2 8.0 10.3 16.6 10.9 11.5 14.3 7.5 14.2 27.5 9.3 3.8 10.5 17.7 11.7 9.7 7.1 20.0 25.1 24.2 5.6 6.7 7.8 13.0 9.7 5.8 23.7 15.2 6.7 6.9 11.9 13.1 14.8 38.0 10.6 7.1 4.7 5.4 9.9 4.3 6.8 3.9 8.3 5.2 4.7 6.3 8.4 5.6 5.8 6.6 3.3 7.9 3.7 4.9 3.8 16.6 18.7 32.7 22.7 15.8 14.4 16.5 15.4 36.9 17.3 MTREX "Dob1, fSAP118, KIAA0052, Mtr4, SKIV2L2" ENSG00000039123 "Mtr4 exosome RNA helicase" P42285 5 55307760-55425581 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, rRNA processing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037379 Supported Supported Nucleoplasm Nucleoplasm "HPA037379: AB_10601713" "unprognostic (7.71e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-3)" "unprognostic (1.32e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (1.79e-2)" "unprognostic (5.08e-1)" "unprognostic (4.17e-2)" "unprognostic (1.46e-2)" "unprognostic (5.05e-2)" "unprognostic (7.67e-2)" "unprognostic (1.11e-2)" "unprognostic (2.09e-1)" "unprognostic (3.98e-1)" "unprognostic (2.86e-1)" "unprognostic (2.11e-1)" 23.6 23.6 26.1 24.9 24.0 18.7 24.1 40.6 31.2 22.0 19.3 15.2 28.8 27.6 26.2 17.8 23.3 20.0 22.4 24.3 22.0 16.0 21.2 22.7 19.7 24.7 21.1 21.5 25.9 25.8 35.8 45.0 19.0 26.6 25.6 21.7 10.4 21.8 28.7 71.3 23.8 24.3 20.9 37.5 20.9 20.6 22.3 21.5 29.7 29.3 19.2 21.7 24.4 23.4 9.8 10.9 5.8 10.3 5.9 10.4 4.0 14.2 20.0 14.6 15.5 12.3 13.0 19.6 13.1 10.0 14.8 18.8 21.3 18.7 27.6 15.5 11.5 9.8 28.3 17.9 22.2 4.9 23.5 18.9 18.8 16.3 11.4 11.1 12.5 10.2 12.3 15.6 19.0 12.8 22.3 16.0 14.2 12.9 11.9 14.6 13.2 19.4 14.6 16.3 12.1 16.0 20.8 18.0 11.1 14.9 8.4 12.8 20.3 16.1 11.5 3.8 9.6 10.6 21.9 11.8 12.3 23.8 9.7 25.4 14.7 4.9 6.6 5.8 10.4 6.1 10.0 8.8 7.7 9.7 7.9 9.8 8.1 8.3 1.9 5.9 10.3 10.9 7.5 4.0 26.1 24.0 40.6 31.2 22.0 16.0 21.1 21.5 26.6 21.5 MUTYH MYH ENSG00000132781 "MutY DNA glycosylase" Q9UIF7 1 45329163-45340470 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA008732 Uncertain Supported Nucleoplasm Nucleoplasm "HPA008732: AB_1854219" "unprognostic (6.30e-3)" "unprognostic (7.12e-2)" "unprognostic (6.29e-2)" "unprognostic (8.80e-2)" "unprognostic (3.43e-1)" "unprognostic (5.16e-3)" "prognostic unfavourable (4.76e-8)" "unprognostic (2.80e-2)" "unprognostic (7.12e-3)" "unprognostic (3.05e-2)" "unprognostic (7.80e-2)" "unprognostic (1.14e-1)" "prognostic unfavourable (7.25e-5)" "unprognostic (3.50e-3)" "unprognostic (1.62e-1)" "unprognostic (5.57e-2)" "unprognostic (5.49e-3)" 7.7 8.4 10.3 12.7 14.8 11.1 8.3 31.6 12.4 10.5 10.1 15.1 11.0 11.1 11.5 9.8 8.3 11.0 10.0 6.1 10.9 7.3 9.7 9.0 7.2 14.0 13.6 10.1 12.9 8.4 7.5 12.5 12.5 11.6 9.1 11.0 12.6 9.5 11.7 8.5 11.1 9.8 7.5 12.6 12.8 11.8 4.9 16.6 14.1 11.9 7.4 12.0 9.3 9.2 7.2 6.5 1.9 8.9 6.6 15.4 6.3 4.9 4.4 10.3 7.0 7.4 5.5 17.9 3.5 4.8 7.5 6.2 9.3 7.1 14.1 6.2 2.4 7.8 5.4 6.4 3.5 11.6 4.1 6.9 7.0 6.6 6.8 5.9 5.0 3.6 6.6 10.1 16.9 5.4 10.7 5.5 3.2 8.1 16.2 5.6 25.9 5.4 22.0 7.9 7.6 3.9 9.5 9.3 7.4 7.6 5.9 11.7 4.7 6.8 3.4 6.6 4.1 5.0 5.5 8.4 9.6 8.6 5.7 9.0 5.0 1.5 5.6 1.9 9.8 8.9 15.4 7.2 10.2 9.9 6.5 7.2 11.3 11.0 0.9 6.6 6.8 5.5 10.3 6.3 10.3 14.8 31.6 12.4 10.9 7.3 13.6 10.1 11.6 16.6 NAALAD2 "GCPIII, NAALADASE2" ENSG00000077616 "N-acetylated alpha-linked acidic dipeptidase 2" Q9Y3Q0 11 90131515-90192894 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 44.1" "Group enriched" "Detected in some" 5 "CACO-2: 19.7;SH-SY5Y: 6.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 12 "monocytes: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060820, HPA065419" Approved Approved Nucleoplasm Nucleoplasm "HPA060820: , HPA065419: " "unprognostic (1.68e-1)" "unprognostic (2.66e-3)" "unprognostic (1.49e-1)" "unprognostic (4.52e-3)" "unprognostic (4.73e-3)" "unprognostic (2.97e-1)" "unprognostic (3.82e-3)" "unprognostic (1.77e-2)" "unprognostic (2.44e-1)" "unprognostic (2.30e-1)" "unprognostic (3.30e-2)" "unprognostic (8.00e-2)" "unprognostic (9.97e-4)" "unprognostic (1.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.63e-2)" "unprognostic (2.93e-1)" 7.7 13.0 5.3 1.8 9.9 1.1 3.1 2.1 9.8 7.8 2.1 3.7 2.8 1.3 10.3 5.4 1.8 4.7 3.7 2.5 5.5 7.4 2.7 1.7 2.8 1.6 6.5 5.0 12.9 2.5 0.9 44.1 8.8 11.9 5.2 2.2 5.8 1.9 3.7 2.1 1.5 2.1 3.5 6.2 4.4 1.8 16.6 7.4 0.0 1.7 1.7 1.2 1.8 3.8 0.0 0.1 0.0 2.4 0.0 0.1 0.1 0.1 0.2 1.9 0.1 0.6 0.1 2.4 0.1 0.1 0.1 0.0 19.7 0.7 0.3 0.2 0.0 0.3 1.4 0.0 0.0 0.0 0.4 1.8 0.4 1.7 0.2 0.1 0.1 2.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.3 0.3 1.9 0.2 0.3 0.0 0.2 0.0 0.0 0.2 6.6 0.0 0.2 0.0 0.2 0.4 2.5 0.1 1.6 0.4 0.3 1.1 0.3 0.3 0.7 0.3 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.1 0.1 5.3 9.9 2.1 9.8 5.5 7.4 6.5 5.0 11.9 7.4 NAALADL1 ENSG00000168060 "N-acetylated alpha-linked acidic dipeptidase like 1" Q9UQQ1 11 65044818-65058549 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "blood: 49.5;intestine: 123.4" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.3;fHDF/TERT166: 6.7;HHSteC: 18.6;HSkMC: 12.2;SCLC-21H: 9.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 49.5" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047123 Enhanced Uncertain Cytosol Cytosol "HPA047123: " "unprognostic (2.98e-2)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "unprognostic (8.76e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-3)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.75e-4)" "unprognostic (2.10e-3)" "unprognostic (3.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.80e-2)" 4.1 0.9 1.4 3.3 1.6 7.0 4.1 1.9 1.4 6.0 54.3 1.2 2.6 7.8 7.2 1.8 2.7 4.4 3.4 3.5 1.3 0.6 2.3 1.2 3.4 5.2 1.5 1.5 6.2 1.0 0.9 2.0 1.5 1.6 4.6 2.6 3.1 2.3 4.8 2.0 1.6 123.4 4.3 1.4 5.0 2.8 1.8 1.2 1.8 1.8 2.3 2.9 3.1 5.4 8.8 4.9 49.5 6.3 22.2 12.9 7.0 0.0 0.0 0.1 0.2 0.4 5.3 0.9 2.0 0.0 2.5 1.1 0.0 0.0 0.1 0.0 6.7 0.0 0.0 0.1 0.0 0.7 0.3 0.0 0.1 3.0 18.6 0.0 0.0 12.2 0.0 2.4 0.0 3.2 0.0 0.2 0.0 0.2 0.2 0.6 0.0 0.1 0.1 0.0 0.8 0.2 0.0 9.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.7 0.0 0.1 0.1 49.5 6.3 10.3 9.5 4.3 4.9 8.0 7.6 4.8 4.9 8.8 8.8 4.9 1.1 22.2 2.5 0.2 12.9 7.0 1.4 1.6 1.9 1.4 1.3 0.6 1.5 1.5 1.6 1.2 NAGA D22S674 ENSG00000198951 Alpha-N-acetylgalactosaminidase P17050 22 42058354-42070842 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "classical monocyte: 38.5;intermediate monocyte: 47.6;myeloid DC: 37.9;non-classical monocyte: 46.1;plasmacytoid DC: 23.2" "Group enriched" "Detected in all" 9 "dendritic cells: 37.9;monocytes: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000649 Enhanced "Intracellular and membrane" 2300000 "HPA000649: AB_1079448" "unprognostic (3.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.45e-3)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (4.27e-1)" "unprognostic (1.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.93e-1)" "unprognostic (3.64e-2)" "unprognostic (3.68e-2)" "unprognostic (1.92e-3)" "unprognostic (8.95e-2)" "unprognostic (2.53e-1)" 23.7 13.5 12.1 20.3 14.5 11.3 12.5 11.8 10.3 16.3 18.3 15.0 10.7 13.2 18.9 16.1 14.5 17.3 16.5 15.8 10.1 8.6 17.9 28.2 19.9 32.6 12.6 7.3 18.1 9.5 27.8 13.1 45.3 11.5 15.2 18.0 19.8 16.6 14.5 9.2 9.9 25.6 18.7 11.4 22.0 14.1 9.3 13.2 12.0 15.0 11.4 17.9 17.3 14.5 2.1 37.9 4.9 47.6 3.4 3.4 19.2 9.0 4.6 7.4 13.1 12.9 14.8 5.4 7.5 15.4 12.9 13.5 10.3 13.4 4.4 4.6 16.2 6.4 5.6 9.1 7.7 10.1 7.1 10.9 7.1 6.9 7.5 9.0 65.2 10.1 8.0 11.6 4.9 21.3 4.0 18.9 10.2 10.5 3.3 3.7 1.9 6.2 7.5 3.7 7.8 10.0 10.8 2.3 2.6 9.9 9.1 9.8 13.6 16.7 11.4 9.1 11.1 5.8 6.7 10.5 10.5 3.5 9.7 17.3 11.2 4.9 38.5 4.6 2.8 47.6 2.8 2.1 2.9 2.6 37.9 1.5 1.9 1.8 1.9 3.4 46.1 23.2 3.4 19.2 12.1 14.5 11.8 10.3 10.1 8.6 12.6 7.3 11.5 13.2 NAGLU NAG ENSG00000108784 N-acetyl-alpha-glucosaminidase P54802 17 42536172-42544449 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Charcot-Marie-Tooth disease, Disease mutation, Mucopolysaccharidosis, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038815 Supported "Intracellular and membrane" 300000000 "HPA038815: AB_10697398" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (6.48e-2)" "prognostic favourable (4.17e-4)" "prognostic unfavourable (6.59e-4)" "unprognostic (1.46e-1)" "unprognostic (1.75e-3)" "unprognostic (3.09e-2)" "unprognostic (2.20e-1)" "unprognostic (6.68e-2)" "prognostic favourable (6.90e-4)" "unprognostic (8.07e-2)" "prognostic favourable (2.58e-6)" "unprognostic (2.25e-1)" "unprognostic (8.74e-3)" "unprognostic (2.15e-2)" "unprognostic (1.62e-1)" 21.1 21.0 10.2 8.4 15.9 10.7 18.3 5.5 11.4 16.9 17.1 19.1 16.3 14.8 19.3 20.6 11.9 14.6 21.4 11.5 10.7 5.9 31.3 50.1 16.3 12.5 21.6 8.0 20.4 38.9 10.6 12.7 23.5 12.1 14.8 10.2 20.9 32.4 12.3 9.1 13.2 17.3 10.1 13.5 22.5 17.0 9.8 20.5 8.9 20.7 8.9 12.3 16.1 12.7 4.8 6.0 3.8 5.8 4.3 5.8 2.4 5.9 20.9 4.2 9.5 41.9 13.9 14.2 9.1 21.7 9.6 12.3 5.6 15.5 7.7 9.3 14.0 14.6 3.7 4.4 2.1 5.9 7.7 4.1 10.9 11.6 14.0 5.0 10.9 16.5 6.8 5.2 6.6 12.5 6.1 15.5 10.6 14.4 0.8 8.6 4.9 2.7 3.2 9.1 17.8 12.7 13.8 6.3 9.6 5.0 6.9 7.7 31.8 5.3 9.7 23.4 3.9 9.3 5.9 20.6 9.3 6.4 14.3 5.4 16.6 2.3 5.5 3.8 5.6 3.7 5.8 4.8 2.4 3.1 4.5 4.6 4.3 3.5 2.5 4.3 5.8 6.0 0.5 2.4 10.2 15.9 5.5 11.4 10.7 5.9 21.6 8.0 12.1 20.5 NAGPA "APAA, UCE" ENSG00000103174 "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase" Q9UK23 16 5024844-5034141 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064055 Approved 3600000 "HPA064055: " "unprognostic (9.93e-2)" "unprognostic (1.61e-2)" "unprognostic (2.08e-2)" "unprognostic (2.21e-2)" "unprognostic (7.12e-3)" "unprognostic (3.30e-3)" "prognostic unfavourable (4.67e-4)" "unprognostic (1.05e-2)" "unprognostic (2.98e-2)" "unprognostic (1.35e-1)" "unprognostic (9.51e-3)" "unprognostic (9.41e-2)" "prognostic unfavourable (2.67e-5)" "unprognostic (1.26e-1)" "unprognostic (6.09e-2)" "unprognostic (7.47e-2)" "unprognostic (1.02e-1)" 8.3 6.3 9.9 9.0 20.1 8.7 4.7 4.7 25.0 6.8 8.5 4.6 5.8 11.4 6.2 4.7 6.1 4.8 5.6 5.0 15.3 5.3 7.2 7.6 7.6 9.1 5.0 9.5 4.2 7.3 7.6 4.9 6.8 6.6 4.9 5.1 4.0 6.0 6.2 6.7 8.5 9.2 5.5 4.4 10.9 12.4 2.7 5.5 4.3 5.1 2.6 5.6 6.0 4.4 9.5 26.5 5.1 20.9 5.1 9.9 9.7 1.5 5.9 1.0 6.4 2.5 3.3 6.7 4.4 7.9 5.8 7.3 4.9 12.3 0.6 5.6 6.0 4.6 2.7 4.9 1.7 7.2 8.3 2.1 3.8 31.8 8.2 5.3 9.3 5.0 5.1 3.8 1.7 9.0 6.8 8.8 3.5 6.7 2.4 14.2 3.1 6.3 6.4 2.4 11.6 3.7 2.3 2.6 3.5 3.5 8.8 9.0 6.0 6.5 6.6 6.4 4.6 14.8 3.3 4.8 3.7 1.4 3.0 8.1 5.3 1.2 20.9 5.1 9.9 18.2 7.9 9.5 9.8 8.8 26.5 8.3 8.1 7.4 0.6 5.1 11.7 6.8 8.7 9.7 9.9 20.1 4.7 25.0 15.3 5.3 5.0 9.5 6.6 5.5 NANP "C20orf147, dJ694B14.3, HDHD4, MGC26833" ENSG00000170191 "N-acetylneuraminic acid phosphatase" Q8TBE9 20 25612935-25624175 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050342 Uncertain Approved "Nuclear membrane" "Nuclear membrane" "HPA050342: AB_2681098" "unprognostic (8.72e-2)" "unprognostic (1.88e-1)" "unprognostic (7.42e-3)" "unprognostic (6.01e-2)" "unprognostic (5.59e-2)" "unprognostic (2.12e-1)" "prognostic unfavourable (9.01e-6)" "unprognostic (3.20e-1)" "unprognostic (3.75e-2)" "unprognostic (7.70e-3)" "unprognostic (1.24e-1)" "unprognostic (3.46e-1)" "unprognostic (2.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.76e-1)" "unprognostic (1.71e-2)" "unprognostic (9.42e-2)" 10.0 14.0 6.3 6.0 7.4 6.9 7.2 13.3 8.2 6.3 6.4 4.1 4.3 7.1 6.9 5.7 9.5 6.2 6.2 6.8 4.3 4.8 11.6 12.5 6.7 4.4 4.2 3.3 12.0 7.4 8.0 8.6 6.0 6.5 5.6 6.2 7.1 7.8 6.1 9.2 4.9 7.6 6.9 5.6 7.1 6.2 6.6 3.7 18.2 9.0 6.0 6.8 7.4 6.8 1.7 6.4 1.7 4.5 4.9 4.2 2.3 11.1 6.5 5.3 7.7 8.6 9.2 7.8 5.7 11.2 7.6 9.7 5.8 7.6 4.0 6.5 10.8 7.1 8.1 8.2 14.8 1.4 4.8 10.0 3.1 15.6 7.2 7.6 3.0 8.0 4.1 8.5 10.9 6.3 8.4 7.2 9.2 6.1 15.0 3.7 3.9 10.2 7.5 11.1 4.9 4.4 6.0 10.2 4.2 6.3 10.2 6.7 4.4 6.5 5.3 12.1 9.0 11.1 8.0 3.8 3.5 10.0 3.4 17.7 7.2 0.4 4.5 1.7 2.8 4.5 4.2 1.4 2.0 2.1 6.4 1.7 1.8 3.1 0.3 4.9 2.4 1.4 1.7 2.3 6.3 7.4 13.3 8.2 4.3 4.8 4.2 3.3 6.5 3.7 NAPEPLD "C7orf18, FMP30, NAPE-PLD" ENSG00000161048 "N-acyl phosphatidylethanolamine phospholipase D" Q6IQ20 7 103099776-103149560 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019832, HPA024338" Approved Enhanced Cytosol Cytosol "HPA019832: AB_1844422, HPA024338: " "unprognostic (3.62e-1)" "unprognostic (1.86e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.58e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" "unprognostic (6.39e-3)" "unprognostic (2.70e-2)" "unprognostic (1.20e-1)" "unprognostic (2.81e-2)" "unprognostic (3.21e-1)" "prognostic favourable (7.32e-6)" "unprognostic (8.83e-2)" "unprognostic (1.19e-1)" "unprognostic (1.42e-1)" "unprognostic (2.41e-2)" 3.8 5.3 8.6 3.8 14.0 3.1 3.9 13.9 18.5 5.1 8.8 17.2 3.7 15.9 4.9 3.5 2.6 6.5 6.1 4.2 6.4 5.5 15.1 7.4 4.3 3.8 15.0 11.6 9.7 4.1 8.5 6.2 2.9 10.3 5.4 10.1 5.0 4.2 4.1 5.0 5.7 10.8 4.5 9.7 6.6 11.2 11.1 16.7 5.3 8.8 0.9 3.8 6.9 4.6 7.9 3.7 5.7 4.6 2.9 7.6 2.5 4.6 6.2 4.0 3.6 3.6 3.9 0.6 3.0 2.8 2.1 3.4 2.7 6.2 4.2 5.1 2.3 4.3 2.8 1.0 2.5 6.5 3.9 1.7 3.7 1.2 0.9 3.7 1.8 2.2 1.2 1.9 0.0 3.4 2.0 4.5 4.0 1.7 4.4 2.0 3.7 7.3 2.8 1.8 2.2 7.6 2.2 2.9 3.9 8.2 2.6 1.8 1.7 2.1 3.0 5.9 4.2 12.0 3.7 5.6 6.1 3.6 4.2 2.7 11.3 0.2 3.1 5.7 4.9 4.6 4.4 7.4 5.3 5.8 3.7 7.9 7.6 5.6 0.3 2.9 3.0 2.7 4.7 2.5 8.6 14.0 13.9 18.5 6.4 5.5 15.0 11.6 10.3 16.7 NAV2 "FLJ10633, FLJ11030, FLJ23707, HELAD1, KIAA1419, POMFIL2, RAINB1" ENSG00000166833 "Neuron navigator 2" Q8IVL1 11 19350724-20121598 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 64.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 34.8;SH-SY5Y: 31.7;TIME: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.9" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011755, HPA011891" Approved Supported Nucleoplasm Nucleoplasm "HPA011755: AB_1854319, HPA011891: AB_1854318" "unprognostic (7.71e-2)" "unprognostic (2.37e-1)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.76e-3)" "unprognostic (3.01e-2)" "unprognostic (3.86e-2)" "unprognostic (1.54e-1)" "unprognostic (1.00e-1)" "unprognostic (3.53e-3)" "unprognostic (1.84e-1)" "unprognostic (2.83e-2)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (6.43e-2)" "unprognostic (3.28e-2)" 14.8 3.1 7.9 4.7 12.5 3.1 13.8 13.8 16.1 10.2 17.6 16.1 8.6 5.1 9.3 13.4 7.8 5.7 3.2 64.6 9.9 7.0 12.3 18.7 11.2 3.0 16.5 11.5 4.7 10.8 10.1 6.6 16.2 23.5 7.9 6.3 8.6 16.5 11.8 3.4 7.9 4.7 13.0 32.2 2.5 9.9 2.1 12.6 0.0 20.1 1.8 5.3 6.0 8.6 0.3 1.9 0.0 0.5 0.0 0.3 0.0 5.9 1.7 3.9 0.4 13.2 8.5 4.2 5.0 8.6 6.6 5.0 6.7 0.8 0.0 0.2 7.5 0.7 0.2 3.9 7.8 1.0 0.4 0.1 8.8 7.6 2.4 0.0 0.2 5.5 10.2 3.1 34.8 8.8 0.7 3.0 19.0 6.3 0.0 0.0 9.2 5.0 0.0 18.0 0.9 5.6 1.7 6.8 31.7 3.8 3.0 5.7 0.1 0.0 24.5 15.5 2.3 18.3 4.7 1.0 0.5 0.0 5.3 0.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.5 1.9 0.0 0.0 7.9 12.5 13.8 16.1 9.9 7.0 16.5 11.5 23.5 12.6 NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862906 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" 86000 Vesicles "Cell Junctions" "HPA015634: AB_1854386, HPA021506: AB_1854385" "unprognostic (3.84e-2)" "unprognostic (7.47e-2)" "unprognostic (9.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-3)" "unprognostic (1.38e-3)" "unprognostic (8.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.21e-2)" "unprognostic (4.44e-3)" "unprognostic (1.27e-1)" "unprognostic (2.70e-2)" "unprognostic (6.22e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-3)" 10.5 30.2 8.6 9.4 11.1 5.2 10.5 15.5 14.6 13.4 14.1 7.4 16.1 14.1 9.8 13.9 9.0 8.3 16.1 9.8 8.0 9.5 29.7 24.2 16.1 7.2 9.4 6.6 12.7 20.6 13.6 16.5 19.8 10.3 15.1 9.1 14.7 18.1 13.8 10.0 9.1 23.5 9.8 4.7 13.4 12.7 6.5 10.0 5.8 22.7 7.0 9.6 13.6 9.5 4.2 7.7 15.2 13.4 3.0 5.1 7.4 2.9 3.0 3.0 6.9 10.1 3.8 5.9 2.7 9.3 8.1 11.8 17.4 3.3 1.0 7.0 3.6 1.7 6.3 2.5 3.1 2.5 4.2 1.5 1.8 20.3 18.1 1.9 8.5 6.3 4.7 9.7 5.0 7.2 3.2 7.2 4.1 5.3 1.6 2.9 2.3 2.4 2.1 1.6 10.4 13.3 6.5 2.3 1.3 3.0 4.0 7.1 7.7 8.7 3.0 5.3 3.1 7.4 4.8 8.9 14.2 2.1 3.9 4.8 3.7 6.4 13.4 8.7 5.1 10.3 4.2 3.9 3.9 4.1 7.7 4.2 4.0 3.9 15.2 3.0 9.2 4.3 4.8 7.4 8.6 11.1 15.5 14.6 8.0 9.5 9.4 6.6 10.3 10.0 NEU2 SIAL2 ENSG00000115488 "Neuraminidase 2" Q9Y3R4 2 233032672-233035057 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "skin 1: 6.1" "Group enriched" "Detected in some" 4 "A-431: 1.1;BEWO: 1.6;PC-3: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.2;hippocampal formation: 1.1" CAB022336 Uncertain 9000 "CAB022336: " "unprognostic (1.30e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NEU3 ENSG00000162139 "Neuraminidase 3" Q9UQ49 11 74988134-75018893 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 44.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038729, HPA070381" Approved Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA038729: , HPA070381: " "unprognostic (1.67e-1)" "unprognostic (2.10e-1)" "unprognostic (2.55e-2)" "unprognostic (1.13e-3)" "unprognostic (2.95e-2)" "unprognostic (5.42e-2)" "unprognostic (1.63e-1)" "unprognostic (5.11e-2)" "unprognostic (3.91e-3)" "unprognostic (8.50e-2)" "prognostic favourable (5.98e-4)" "unprognostic (3.57e-3)" "unprognostic (3.80e-2)" "unprognostic (3.79e-1)" "unprognostic (2.38e-1)" "unprognostic (3.73e-1)" "unprognostic (1.84e-1)" 5.4 13.4 3.7 10.5 6.9 17.0 5.4 7.9 9.1 4.0 3.9 3.0 4.1 3.6 5.4 4.8 3.9 4.4 3.6 5.9 4.0 4.5 4.3 6.7 8.7 9.0 3.8 6.6 7.2 7.3 15.1 11.2 3.1 4.2 9.7 5.4 5.6 4.8 4.6 19.1 6.7 4.7 4.0 3.5 5.5 5.1 44.6 3.0 19.0 6.8 3.5 7.5 4.5 3.1 3.2 3.8 5.8 6.4 1.2 4.2 2.2 4.6 4.0 3.4 6.6 2.6 2.5 3.8 4.5 2.9 5.2 4.0 13.7 3.9 13.3 4.6 3.6 4.3 8.3 5.8 7.9 7.0 4.4 11.0 7.5 5.6 2.9 17.2 10.6 3.0 4.9 5.2 8.1 3.7 17.7 10.0 5.9 5.0 16.9 8.9 4.2 5.4 14.9 9.0 11.7 6.4 4.9 6.3 4.0 6.9 4.6 20.3 9.9 4.5 5.6 6.5 6.5 4.3 4.5 8.3 8.0 26.7 1.9 8.9 5.5 2.1 6.4 5.8 4.1 3.7 3.0 2.8 3.2 3.9 3.8 3.2 3.5 4.2 3.3 1.2 4.6 2.7 2.3 2.2 3.7 6.9 7.9 9.1 4.0 4.5 3.8 6.6 4.2 3.0 NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241808825-241817413 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 27.1;liver: 42.9" "Group enriched" "Detected in some" 21 "Hep G2: 22.0;HMC-1: 30.7" "Group enriched" "Detected in some" 7 "colorectal cancer: 2.3;glioma: 6.0;liver cancer: 6.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037394 Enhanced "HPA037394: " "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.85e-1)" "unprognostic (3.68e-4)" "unprognostic (3.76e-2)" "unprognostic (1.57e-1)" "unprognostic (8.70e-2)" "unprognostic (8.62e-2)" "unprognostic (1.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.92e-1)" "unprognostic (8.11e-4)" "unprognostic (2.00e-2)" "unprognostic (3.82e-1)" "unprognostic (6.64e-3)" "unprognostic (1.55e-2)" 0.6 0.5 6.5 0.7 5.3 5.7 0.3 1.9 7.0 0.6 13.9 4.9 0.0 9.3 0.3 0.3 0.7 1.1 2.6 0.6 6.4 5.8 1.4 42.9 0.4 0.5 6.9 4.4 0.4 0.3 0.3 0.4 0.4 3.8 0.5 6.1 0.0 0.4 0.4 3.6 0.3 27.1 0.4 4.1 0.5 0.5 0.6 2.3 0.0 0.4 2.8 0.3 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.5 5.3 1.9 4.0 6.4 5.8 6.9 4.4 3.8 2.3 NGLY1 "FLJ11005, PNG1" ENSG00000151092 "N-glycanase 1" Q96IV0 3 25718944-25790039 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036825 Approved "Intracellular and membrane" "HPA036825: AB_10672231" "unprognostic (3.65e-2)" "unprognostic (8.65e-2)" "prognostic favourable (1.17e-5)" "unprognostic (2.96e-2)" "unprognostic (1.72e-2)" "unprognostic (1.59e-2)" "prognostic unfavourable (1.96e-6)" "unprognostic (2.20e-1)" "unprognostic (2.34e-1)" "unprognostic (3.73e-3)" "unprognostic (2.55e-1)" "unprognostic (4.23e-2)" "unprognostic (4.92e-3)" "unprognostic (1.07e-2)" "unprognostic (2.47e-1)" "unprognostic (9.08e-2)" "unprognostic (1.89e-2)" 10.7 14.4 11.4 19.6 11.4 12.9 15.0 17.1 15.0 9.5 12.4 6.9 11.7 10.5 10.2 13.8 13.2 8.4 10.5 14.3 12.0 9.0 12.8 18.1 13.9 17.4 9.5 12.5 10.6 20.7 9.0 11.3 8.7 11.0 10.9 15.2 7.8 12.4 18.0 46.6 9.0 11.2 8.7 10.1 14.6 11.9 42.0 9.0 18.0 10.3 10.9 18.1 11.5 10.6 26.1 39.7 19.9 10.8 22.6 14.7 10.3 12.2 10.5 5.9 12.4 11.4 10.4 8.4 10.5 8.9 13.3 12.0 6.5 9.3 31.2 12.0 8.9 5.5 19.8 5.5 18.1 14.7 8.4 23.2 8.0 10.5 12.6 21.3 12.7 9.3 7.5 14.6 13.6 14.2 21.9 22.4 13.5 5.3 25.3 12.6 7.9 19.0 25.9 7.7 22.2 12.2 15.1 3.6 4.4 15.3 14.7 9.7 13.9 17.8 9.6 10.5 10.8 12.6 13.5 27.7 23.8 21.7 12.6 23.1 8.2 19.9 10.8 18.9 13.7 10.1 14.7 26.1 13.8 12.6 16.3 21.7 14.0 13.6 12.8 22.6 8.4 39.7 10.4 10.3 11.4 11.4 17.1 15.0 12.0 9.0 9.5 12.5 11.0 9.0 NIT2 ENSG00000114021 "Nitrilase family member 2" Q9NQR4 3 100334701-100361635 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 41.1" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036999 Approved Supported Centrosome,Cytosol 960000 Cytosol Centrosome "HPA036999: AB_10672105" "unprognostic (3.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.06e-3)" "prognostic unfavourable (4.62e-4)" "unprognostic (6.28e-2)" "unprognostic (2.10e-1)" "unprognostic (4.56e-1)" "unprognostic (1.12e-1)" "unprognostic (6.60e-3)" "unprognostic (2.21e-1)" "unprognostic (6.68e-2)" "unprognostic (7.92e-2)" "unprognostic (1.37e-2)" "unprognostic (4.48e-2)" "unprognostic (1.29e-1)" "unprognostic (8.26e-2)" "unprognostic (1.47e-3)" 9.9 7.4 6.7 5.4 9.9 5.9 12.4 3.7 10.5 6.4 7.2 6.1 10.6 5.5 6.6 13.3 9.2 7.9 7.1 7.4 5.8 6.3 29.8 41.1 5.6 8.9 5.9 8.0 7.2 8.5 4.7 7.6 4.9 7.7 7.2 6.8 11.3 8.2 10.2 14.7 7.7 5.3 7.0 5.4 5.7 6.8 3.3 3.3 4.4 10.8 14.5 10.5 8.2 5.6 4.2 5.9 1.5 2.4 3.0 4.3 1.3 9.9 9.9 1.2 5.1 8.9 12.1 6.2 4.1 6.0 9.7 9.2 8.4 11.2 9.9 6.2 5.8 7.5 4.5 11.0 11.6 3.1 2.3 7.2 3.2 4.3 10.8 4.7 4.9 7.6 16.7 5.1 8.5 6.1 3.3 8.0 11.8 9.4 3.1 4.3 4.4 15.0 3.5 4.2 9.7 16.0 6.2 6.9 3.2 5.6 9.6 6.1 7.1 4.4 4.4 6.1 2.5 2.9 3.5 4.9 5.4 8.5 9.6 7.9 7.6 0.4 2.4 1.1 3.3 2.1 4.3 4.2 3.1 2.5 5.9 3.7 3.6 3.5 1.5 3.0 1.6 1.8 3.1 1.3 6.7 9.9 3.7 10.5 5.8 6.3 5.9 8.0 7.7 3.3 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722196-65871725 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.7;intermediate monocyte: 5.9;myeloid DC: 4.1;non-classical monocyte: 4.1" "Group enriched" "Detected in many" 5 "dendritic cells: 4.1;monocytes: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria 53000 Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavourable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favourable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 4.5 2.4 7.6 4.7 10.5 2.9 7.3 2.8 11.9 4.1 6.8 5.8 1.0 2.4 5.8 5.0 5.2 3.3 2.7 5.1 7.2 7.6 7.5 18.9 3.4 5.1 8.7 8.5 4.0 11.0 3.6 2.4 4.9 9.8 5.4 6.5 2.0 4.3 2.6 15.0 5.7 5.3 5.5 10.9 5.8 7.5 2.4 6.2 1.8 5.5 7.9 4.0 4.3 3.3 0.9 4.1 0.6 5.9 0.9 0.7 1.8 9.2 8.9 5.3 8.7 6.6 11.4 10.6 9.3 3.9 5.5 6.0 5.0 5.5 13.2 11.8 11.2 7.4 6.8 14.4 9.6 3.9 4.6 3.6 6.6 12.8 5.7 8.3 2.2 8.7 7.9 7.6 9.1 15.5 7.8 2.8 11.8 7.1 5.7 7.5 16.1 2.5 6.7 11.2 20.8 9.0 4.1 16.3 8.5 7.5 7.8 7.7 9.3 9.9 8.9 3.7 4.4 5.3 7.0 2.4 4.8 5.8 5.6 16.3 5.5 0.2 4.7 0.2 0.2 5.9 0.3 0.9 0.4 0.3 4.1 0.9 0.7 0.5 0.6 0.9 4.1 0.2 0.1 1.8 7.6 10.5 2.8 11.9 7.2 7.6 8.7 8.5 9.8 6.2 NOCT "Ccr4c, CCR4L, CCRN4L, NOC" ENSG00000151014 Nocturnin Q9UK39 4 139015789-139045939 "Enzymes, Predicted intracellular proteins" "Biological rhythms" "Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012287, HPA053714" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA012287: , HPA053714: " "unprognostic (2.16e-1)" "unprognostic (2.16e-3)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (3.36e-3)" "unprognostic (2.00e-3)" "unprognostic (3.24e-1)" "prognostic unfavourable (5.28e-5)" "unprognostic (1.86e-1)" "unprognostic (5.64e-3)" "unprognostic (4.63e-2)" "unprognostic (1.01e-3)" "prognostic unfavourable (1.05e-5)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (3.52e-4)" "prognostic unfavourable (6.23e-4)" 17.5 3.9 3.3 4.9 8.0 38.7 7.4 3.2 7.3 2.7 3.1 2.7 0.0 2.2 2.8 1.5 4.0 2.5 7.9 5.4 4.9 3.7 6.9 25.8 5.1 3.1 3.0 3.1 1.7 4.4 4.0 4.7 9.3 3.7 2.0 2.8 1.8 10.8 1.4 12.0 3.9 10.5 4.5 2.3 3.2 3.0 4.9 2.6 3.7 2.9 11.8 3.9 3.7 4.6 1.9 1.5 6.3 3.1 1.4 2.4 0.2 4.8 5.6 2.2 4.2 5.0 2.1 13.7 7.2 5.2 10.3 7.4 7.5 2.0 16.0 5.8 5.3 3.5 11.5 6.3 9.7 7.2 4.7 7.4 3.4 6.5 4.6 10.8 4.4 2.4 3.1 11.4 7.8 4.5 13.3 5.3 4.5 5.5 7.4 5.7 7.1 6.0 6.1 6.5 5.6 6.9 3.1 8.3 5.5 4.5 5.2 4.1 3.8 8.4 6.7 5.5 7.2 5.2 8.6 4.3 4.0 10.1 5.1 21.5 7.0 1.5 1.4 0.8 2.4 1.5 1.4 1.1 1.1 1.3 0.6 1.9 0.8 1.6 6.3 1.4 3.1 1.5 0.7 0.2 3.3 8.0 3.2 7.3 4.9 3.7 3.0 3.1 3.7 2.6 NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "placenta: 127.4" "Cell line enriched" "Detected in some" 26 "Hep G2: 94.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in female reproductive system" 59000 "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-2)" "unprognostic (4.80e-3)" "unprognostic (1.97e-1)" "unprognostic (9.02e-3)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (6.49e-2)" "unprognostic (8.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (4.48e-6)" "unprognostic (1.76e-1)" "unprognostic (9.88e-2)" "unprognostic (1.22e-3)" "unprognostic (1.00e-1)" 0.2 0.1 1.1 0.2 1.2 0.1 0.2 0.3 1.0 0.2 0.2 0.2 0.5 0.6 1.0 1.3 0.3 0.2 0.3 0.3 0.5 0.9 0.8 10.4 1.8 0.2 0.7 0.4 0.2 0.2 0.0 0.2 127.4 0.6 0.4 0.0 0.2 0.3 0.2 4.9 2.4 0.2 0.2 0.3 0.3 0.9 3.0 0.5 0.2 0.2 0.3 0.2 1.3 1.3 0.7 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.4 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.5 0.6 94.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.3 0.9 0.4 1.3 0.0 1.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 1.2 0.3 1.0 0.5 0.9 0.7 0.4 0.6 0.5 NPEPPS "MP100, PSA" ENSG00000141279 "Aminopeptidase puromycin sensitive" P55786 17 47522942-47623276 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021453, HPA045649" Uncertain Supported Cytosol 2100000 Cytosol "HPA021453: , HPA045649: " "unprognostic (1.63e-1)" "unprognostic (3.15e-2)" "prognostic favourable (3.39e-5)" "unprognostic (2.66e-2)" "unprognostic (1.53e-1)" "unprognostic (5.92e-2)" "prognostic unfavourable (3.67e-5)" "unprognostic (3.84e-2)" "unprognostic (1.22e-1)" "unprognostic (1.77e-1)" "unprognostic (3.85e-2)" "unprognostic (3.63e-2)" "unprognostic (1.93e-1)" "unprognostic (8.55e-2)" "unprognostic (1.52e-1)" "unprognostic (1.23e-2)" "unprognostic (1.07e-1)" 16.0 26.0 27.2 15.9 27.7 11.1 56.1 36.5 33.8 17.1 17.7 9.8 14.6 14.6 16.9 17.1 47.7 17.2 16.3 22.2 24.0 15.6 18.8 11.1 30.3 24.1 16.0 29.7 20.8 16.8 21.2 15.3 17.6 27.2 18.6 20.0 13.3 21.8 16.5 52.3 29.6 17.3 20.4 22.8 15.7 16.2 15.3 16.1 7.0 14.5 14.8 18.1 19.0 30.5 6.9 9.0 23.2 8.6 9.3 9.2 5.4 32.6 21.5 21.7 15.2 25.1 25.3 45.8 14.4 18.7 21.9 21.3 13.8 37.6 19.5 22.4 21.0 19.9 23.8 13.3 34.1 8.7 20.6 23.5 22.2 16.1 14.5 13.2 15.2 19.3 13.1 15.9 8.3 22.5 19.8 11.4 31.0 8.8 17.5 11.8 13.3 19.6 14.2 30.5 17.2 27.3 24.0 17.4 15.0 18.6 10.8 12.8 80.9 9.2 28.7 14.6 10.5 21.8 10.1 23.3 22.4 11.9 20.7 7.0 9.6 10.2 8.6 10.7 9.1 6.6 9.2 6.8 7.3 8.5 8.7 6.9 6.5 7.6 23.2 9.3 6.8 9.0 8.4 5.4 27.2 27.7 36.5 33.8 24.0 15.6 16.0 29.7 27.2 16.1 NRDC "hNRD1, hNRD2, NRD1" ENSG00000078618 "Nardilysin convertase" O43847 1 51789191-51878937 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 96.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053661 Approved Nucleoplasm Nucleoplasm "HPA053661: " "unprognostic (1.22e-1)" "unprognostic (6.52e-2)" "unprognostic (2.14e-2)" "unprognostic (5.62e-2)" "unprognostic (2.61e-1)" "unprognostic (3.25e-2)" "prognostic unfavourable (5.49e-6)" "unprognostic (1.42e-1)" "unprognostic (4.17e-2)" "unprognostic (1.67e-1)" "unprognostic (5.86e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (2.12e-9)" "unprognostic (2.75e-1)" "unprognostic (2.35e-2)" "unprognostic (9.54e-2)" "unprognostic (5.53e-3)" 16.4 15.9 13.4 15.8 17.5 14.5 11.7 14.7 16.9 12.2 13.7 11.0 9.9 11.2 11.8 12.1 14.4 10.9 10.9 25.7 13.1 13.3 12.4 28.5 12.0 13.6 16.2 10.6 11.7 15.9 19.3 21.4 14.2 15.7 13.8 12.1 9.8 11.9 11.3 96.4 19.1 10.3 13.3 14.0 13.6 11.9 32.3 14.5 19.4 11.7 21.5 15.1 13.0 16.0 13.8 18.5 36.3 19.1 15.8 15.1 16.2 47.6 26.8 26.9 38.7 28.3 43.9 31.4 48.1 41.6 35.0 37.2 18.8 18.8 31.4 25.8 36.2 27.8 39.6 37.3 44.4 37.2 19.5 37.5 36.5 16.3 29.1 32.7 28.6 34.9 28.6 51.1 47.5 36.4 49.4 21.1 43.8 17.4 29.6 11.3 47.8 28.9 29.0 32.2 34.6 25.9 27.7 25.9 19.5 43.9 35.3 26.0 23.6 39.9 30.2 30.8 28.6 33.5 40.9 31.5 47.6 29.4 36.4 41.3 35.3 19.3 18.1 26.0 13.7 19.1 13.7 13.8 12.7 15.1 18.5 9.3 12.5 13.4 36.3 15.8 14.5 15.0 14.4 16.2 13.4 17.5 14.7 16.9 13.1 13.3 16.2 10.6 15.7 14.5 NSF "SEC18, SKD2" ENSG00000073969 "N-ethylmaleimide sensitive factor, vesicle fusing ATPase" P46459 17 46590669-46757464 "Enzymes, Predicted intracellular proteins, Transporters" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 35.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003154, CAB009324, HPA071089" Enhanced Enhanced Cytosol 6900 Cytosol "CAB009324: AB_653479, HPA003154: AB_1079508, HPA071089: " "unprognostic (5.70e-2)" "unprognostic (1.50e-1)" "unprognostic (1.07e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.09e-1)" "unprognostic (3.95e-2)" "unprognostic (5.48e-2)" "unprognostic (2.37e-2)" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" "unprognostic (2.07e-2)" "unprognostic (3.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.74e-1)" 1.9 3.6 11.2 2.7 19.1 1.6 2.6 14.1 35.4 2.5 4.0 1.4 1.9 2.7 3.9 2.2 2.8 1.5 13.9 14.4 3.4 2.5 2.2 3.1 12.6 1.3 3.5 6.5 5.5 2.6 2.8 5.5 2.4 2.1 4.3 2.4 3.2 2.2 3.1 1.6 3.0 3.1 3.6 3.4 3.3 1.0 7.2 15.5 10.4 13.3 6.7 11.1 8.8 6.1 13.6 9.1 0.6 5.4 7.6 7.4 8.4 9.8 8.1 7.9 9.3 0.0 15.0 15.1 18.6 1.1 10.2 3.1 13.3 5.3 13.3 0.5 9.8 12.7 8.0 0.4 3.3 6.9 4.3 16.4 6.8 12.7 10.0 8.2 17.9 12.0 10.0 3.9 5.1 16.2 7.2 8.8 14.0 9.2 12.8 8.4 9.5 12.4 0.0 5.9 15.5 18.6 10.3 22.9 8.1 12.1 12.5 17.6 10.1 8.8 6.4 8.1 16.1 10.4 13.3 7.8 8.2 12.1 8.9 6.8 8.2 10.5 15.5 7.2 6.9 8.1 6.0 6.7 12.1 6.2 11.1 8.8 NT5C1A "CN-I, CN-IA, CN1, CN1A, MGC119199, MGC119201" ENSG00000116981 "5'-nucleotidase, cytosolic IA" Q9BXI3 1 39659121-39672038 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 51.9;tongue: 13.9" "Cell line enriched" "Detected in some" 13 "SH-SY5Y: 19.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050283, HPA054158" Supported "HPA050283: , HPA054158: " "unprognostic (7.85e-2)" "unprognostic (1.60e-1)" "unprognostic (6.19e-1)" "unprognostic (1.51e-3)" "unprognostic (7.19e-2)" "unprognostic (2.87e-1)" "unprognostic (3.34e-1)" "unprognostic (1.32e-1)" "unprognostic (3.29e-2)" "unprognostic (1.81e-2)" 0.7 2.8 1.2 0.8 3.0 0.5 0.5 5.6 7.6 0.7 0.5 1.0 0.0 0.5 0.6 2.9 3.0 0.7 0.5 9.8 1.7 1.7 0.9 0.5 0.5 0.5 1.8 4.9 0.7 6.0 0.5 0.5 0.5 6.9 0.9 0.5 0.0 0.7 0.7 51.9 0.5 0.6 0.6 5.2 0.5 0.6 0.7 1.0 0.0 0.5 13.9 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 19.9 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.0 5.6 7.6 1.7 1.7 1.8 4.9 6.9 1.0 NT5C1B "AIRP, CN-IB" ENSG00000185013 "5'-nucleotidase, cytosolic IB" Q96P26 2 18562872-18589572 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 52.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" HPA056683 Uncertain "HPA056683: " "unprognostic (4.18e-2)" "unprognostic (1.20e-2)" "unprognostic (7.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "unprognostic (4.97e-2)" "unprognostic (4.96e-2)" "unprognostic (4.84e-1)" "unprognostic (8.49e-2)" "unprognostic (4.42e-2)" "unprognostic (2.91e-2)" "unprognostic (2.35e-1)" "unprognostic (1.61e-1)" "unprognostic (6.96e-2)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (3.77e-1)" 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.3 0.7 0.0 0.4 0.3 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.8 0.1 0.1 0.1 0.1 0.5 52.6 0.1 0.1 0.5 0.1 0.1 0.5 0.1 1.2 3.7 0.0 0.1 0.7 2.6 0.4 3.2 0.7 0.3 0.0 0.0 0.0 0.5 2.5 0.0 0.0 0.0 0.0 3.5 1.6 0.5 0.0 1.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.9 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 1.1 0.2 0.0 2.9 0.1 0.2 0.7 1.7 0.3 0.7 0.8 0.1 3.0 2.5 1.2 2.6 0.4 1.5 0.8 0.7 1.7 1.5 1.0 2.9 0.5 1.0 0.7 2.0 2.5 0.0 1.2 0.0 0.1 0.0 1.3 0.0 2.3 0.1 1.3 1.3 0.3 1.2 2.6 2.2 0.0 0.7 0.1 3.7 0.5 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 NT5C2 "cN-II, GMP, NT5B, PNT5, SPG65" ENSG00000076685 "5'-nucleotidase, cytosolic II" P49902 10 103088017-103193306 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Allosteric enzyme, Hydrolase" "Cancer-related genes, Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003751 Approved "HPA003751: AB_1854664" "unprognostic (8.18e-2)" "unprognostic (1.98e-1)" "unprognostic (2.55e-2)" "unprognostic (2.46e-1)" "unprognostic (5.54e-2)" "unprognostic (4.87e-3)" "unprognostic (2.24e-2)" "unprognostic (1.72e-1)" "unprognostic (6.41e-2)" "unprognostic (9.59e-2)" "unprognostic (2.93e-3)" "unprognostic (6.20e-2)" "unprognostic (3.26e-2)" "unprognostic (3.70e-2)" "unprognostic (6.40e-2)" "unprognostic (3.43e-1)" "unprognostic (1.50e-1)" 15.0 17.0 17.6 18.2 21.2 31.6 19.7 22.5 19.6 17.5 20.7 25.4 24.5 10.9 24.6 19.6 38.6 14.8 17.0 16.5 16.7 20.7 19.6 15.5 18.8 16.8 21.8 17.3 24.8 19.4 18.7 29.5 16.9 29.1 22.9 17.0 26.2 67.2 21.6 41.6 11.7 13.9 20.4 19.1 20.5 15.9 21.7 14.5 29.7 39.2 16.3 31.5 21.1 31.1 6.7 9.7 23.8 14.5 10.5 8.7 7.1 50.1 20.4 14.2 31.9 12.5 14.0 8.1 25.2 24.5 12.3 12.7 14.8 40.2 24.0 19.6 17.4 25.7 9.4 12.9 14.4 14.5 8.8 17.3 8.7 14.4 22.4 25.0 8.6 21.4 14.4 10.7 17.3 11.2 11.2 16.8 21.2 29.6 22.3 32.4 13.5 25.3 36.5 12.3 6.9 17.6 28.7 4.3 10.7 13.2 10.4 19.7 15.9 19.4 11.4 9.8 9.8 14.0 18.3 14.7 24.4 32.2 9.9 28.9 2.8 19.8 11.7 23.8 8.1 11.9 8.7 6.7 7.0 6.5 9.7 4.2 6.0 6.2 21.4 10.5 14.5 7.3 6.5 7.1 17.6 21.2 22.5 18.0 16.7 20.7 21.8 17.3 29.1 14.5 NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014113-33062797 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010630, HPA029058" Uncertain "Intracellular and membrane" "HPA010630: AB_2668319, HPA029058: AB_10601380" "unprognostic (7.50e-2)" "unprognostic (3.10e-1)" "unprognostic (1.14e-1)" "unprognostic (2.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.56e-2)" "prognostic unfavourable (2.42e-4)" "unprognostic (3.25e-2)" "unprognostic (3.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "prognostic unfavourable (1.70e-4)" "unprognostic (9.37e-2)" "unprognostic (2.05e-1)" "unprognostic (2.12e-3)" "unprognostic (3.43e-3)" 12.3 12.1 9.9 17.0 9.9 15.4 11.4 16.2 12.2 12.0 27.5 7.4 8.1 20.9 14.7 11.6 12.0 9.0 12.9 11.6 9.8 10.3 11.7 10.5 11.6 15.0 10.3 9.8 10.3 19.1 5.5 10.9 10.6 8.4 9.6 27.2 8.5 9.0 8.9 53.3 15.0 19.7 7.5 9.9 18.4 14.5 6.3 8.9 15.4 9.8 28.8 22.8 12.0 11.6 21.4 6.8 36.6 11.4 8.6 18.9 13.3 14.1 10.3 9.6 8.5 7.3 6.4 7.8 15.5 10.1 10.5 14.4 6.4 40.0 35.5 9.0 9.0 21.5 10.4 10.2 15.7 5.5 13.3 16.1 12.2 9.3 7.7 19.2 13.4 7.1 9.1 11.5 23.1 6.9 13.9 9.5 12.9 9.6 7.1 30.1 9.9 9.1 9.5 8.8 21.0 33.6 14.9 10.4 12.9 10.1 19.1 24.2 12.7 10.7 6.0 9.0 8.1 15.3 20.2 19.0 21.6 17.4 7.4 11.9 14.0 26.9 8.0 29.8 9.0 10.2 10.2 21.4 12.1 11.0 6.8 20.5 12.4 10.6 36.6 8.6 11.4 6.4 18.9 13.3 9.9 9.9 16.2 12.2 9.8 10.3 10.3 9.8 8.4 8.9 NT5C3B "cN-IIIB, MGC20781, NT5C3L" ENSG00000141698 "5'-nucleotidase, cytosolic IIIB" Q969T7 17 41825181-41836263 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030786, HPA057095" Approved "HPA030786: AB_10602716, HPA057095: " "unprognostic (3.90e-2)" "unprognostic (5.75e-2)" "unprognostic (8.87e-2)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "prognostic unfavourable (8.11e-5)" "unprognostic (3.40e-2)" "unprognostic (6.05e-2)" "unprognostic (2.31e-1)" "prognostic favourable (2.67e-4)" "unprognostic (3.07e-1)" "unprognostic (7.17e-3)" "unprognostic (2.36e-2)" "unprognostic (4.80e-3)" "unprognostic (7.14e-3)" "unprognostic (1.42e-2)" 10.0 12.4 15.9 8.3 26.2 3.2 18.3 22.8 31.2 11.6 15.6 8.4 10.1 4.4 14.1 21.3 13.9 12.6 11.5 11.4 15.0 14.9 19.2 19.4 11.0 7.9 12.9 16.4 15.5 19.6 21.1 13.7 11.5 13.2 12.6 13.8 12.6 15.9 20.1 7.8 8.6 8.1 22.1 6.7 7.7 12.0 24.8 9.8 1.4 37.8 5.6 10.7 13.3 9.7 5.3 5.2 2.5 5.6 1.0 5.9 4.1 8.6 12.9 22.0 29.0 20.3 17.1 3.1 8.6 25.2 27.6 27.5 10.5 5.0 12.9 4.5 17.6 8.3 21.8 12.2 44.8 6.3 8.6 7.8 13.4 11.1 13.5 0.1 3.2 12.1 11.7 23.3 19.0 15.9 7.3 8.1 19.4 5.0 12.5 3.0 5.9 1.9 10.7 29.3 11.9 12.0 9.3 13.5 6.9 13.0 46.6 4.6 12.6 4.7 10.9 8.5 6.7 14.2 17.7 1.6 6.6 6.3 11.1 0.2 10.4 1.5 5.6 0.5 3.8 1.0 5.8 4.7 5.9 5.1 5.2 5.3 5.4 4.5 2.5 1.0 0.7 2.7 0.8 4.1 15.9 26.2 22.8 31.2 15.0 14.9 12.9 16.4 13.2 9.8 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 108.8;TIME: 63.0;U-87 MG: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 13.4;memory CD8 T-cell: 6.6;naive B-cell: 19.9;naive CD8 T-cell: 17.3" "Group enriched" "Detected in many" 47 "B-cells: 19.9;T-cells: 17.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" 1600000 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavourable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavourable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavourable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 12.2 3.2 9.3 7.7 11.6 0.5 16.6 1.1 6.9 58.8 13.9 3.6 8.1 18.6 33.3 14.8 7.6 12.2 15.4 6.1 5.7 5.5 8.8 26.0 3.4 6.8 6.3 6.6 25.4 1.4 1.6 9.3 42.2 5.3 16.4 15.6 15.3 4.6 17.8 5.7 4.5 14.9 35.3 6.3 7.0 6.0 12.4 4.2 1.6 26.5 7.3 7.1 16.6 20.2 19.9 0.0 0.2 0.0 0.4 17.3 3.9 5.4 2.9 5.0 0.1 11.5 36.7 0.0 35.5 38.9 17.5 32.9 0.0 54.5 0.0 12.8 31.0 2.8 0.0 35.7 41.7 0.0 0.0 0.0 0.8 0.6 5.7 0.0 0.0 9.4 0.4 35.7 22.8 14.5 0.0 0.1 108.8 0.9 0.0 0.0 0.1 3.9 0.1 1.1 0.1 37.9 2.4 0.0 0.6 0.4 2.2 12.0 0.0 0.9 63.0 14.3 0.1 18.0 57.7 2.7 1.7 0.0 98.1 0.0 44.8 0.0 0.0 0.2 2.0 0.0 3.5 13.4 2.3 6.6 0.0 19.9 2.4 17.3 0.2 0.4 0.0 0.0 0.8 3.9 9.3 11.6 1.1 6.9 5.7 5.5 6.3 6.6 5.3 4.2 NTPCR "C1orf57, HCR-NTPase, MGC13186" ENSG00000135778 "Nucleoside-triphosphatase, cancer-related" Q9BSD7 1 232950605-232983882 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028125, HPA054304" Uncertain Approved Cytosol Cytosol "HPA028125: AB_10601091, HPA054304: " "unprognostic (2.67e-1)" "unprognostic (2.28e-2)" "unprognostic (1.63e-2)" "unprognostic (7.59e-2)" "unprognostic (5.85e-3)" "unprognostic (1.04e-1)" "unprognostic (8.70e-3)" "unprognostic (2.12e-1)" "unprognostic (6.00e-2)" "unprognostic (5.03e-3)" "unprognostic (4.78e-2)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.74e-2)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "unprognostic (6.37e-3)" 5.4 9.8 13.2 5.8 14.9 2.5 8.7 14.5 15.9 9.9 8.0 11.1 4.1 5.1 9.6 9.5 8.0 11.3 9.6 10.3 13.3 13.1 8.4 6.1 7.4 6.5 13.7 10.8 12.9 13.4 16.9 8.0 6.3 18.5 8.8 10.3 10.8 10.1 10.0 26.8 9.9 6.8 9.9 12.6 6.3 5.8 11.2 11.0 5.7 13.6 11.1 6.5 7.1 7.4 2.4 1.5 3.3 1.8 1.6 4.3 1.3 2.5 6.1 7.0 3.5 5.2 6.9 0.1 1.7 5.4 5.2 7.1 4.3 2.9 3.9 3.8 3.4 3.3 4.7 6.2 5.7 2.8 8.8 1.1 3.8 5.5 5.4 2.1 2.4 9.1 12.2 5.1 5.1 4.2 3.4 6.0 6.1 1.8 5.4 5.5 6.9 7.3 3.5 4.6 5.6 7.7 3.0 6.1 10.2 2.4 2.0 2.4 5.1 4.8 3.2 4.3 3.6 4.7 4.7 6.8 5.5 4.4 5.1 5.1 6.2 1.1 1.6 0.8 2.1 1.8 2.5 1.6 3.0 1.3 1.5 2.4 4.3 3.5 3.3 1.6 1.6 0.6 3.5 1.3 13.2 14.9 14.5 15.9 13.3 13.1 13.7 10.8 18.5 11.0 NUDT1 MTH1 ENSG00000106268 "Nudix hydrolase 1" P36639 7 2242222-2251146 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 59.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012636 Approved Supported Cytosol Cytosol "HPA012636: AB_1854696" "unprognostic (1.31e-1)" "unprognostic (1.19e-2)" "unprognostic (2.13e-2)" "unprognostic (2.37e-1)" "unprognostic (3.01e-3)" "unprognostic (3.37e-1)" "prognostic unfavourable (4.44e-4)" "unprognostic (2.15e-2)" "unprognostic (4.77e-1)" "unprognostic (3.81e-2)" "unprognostic (3.81e-2)" "unprognostic (1.53e-1)" "prognostic unfavourable (1.30e-7)" "unprognostic (1.29e-1)" "unprognostic (6.71e-2)" "unprognostic (3.49e-2)" "unprognostic (1.70e-1)" 8.8 3.9 7.4 12.6 13.4 37.1 10.8 5.0 10.8 5.9 9.0 8.7 2.2 9.1 8.2 9.2 13.1 6.0 8.1 11.3 8.7 4.7 4.1 2.9 7.2 18.9 8.2 7.0 4.8 4.0 0.7 1.8 5.8 7.2 7.2 6.3 4.0 5.5 4.2 12.0 18.8 9.3 10.5 11.9 11.1 5.5 26.7 5.3 30.7 4.1 14.4 17.2 6.8 8.1 18.3 59.5 11.9 21.3 10.1 20.4 13.0 21.5 34.8 19.1 25.3 7.0 9.7 14.0 9.5 8.3 13.1 15.3 18.7 16.3 22.8 7.8 10.4 26.4 14.5 14.5 7.7 10.1 24.7 17.8 29.3 15.8 1.7 13.8 18.0 6.4 3.8 18.9 6.7 7.0 14.0 25.5 14.5 55.0 25.7 53.8 41.0 21.5 35.9 28.4 19.1 7.1 12.2 19.2 26.6 9.8 28.9 4.4 19.1 36.7 6.5 12.6 48.1 29.0 22.6 19.7 14.9 23.6 12.7 34.4 45.2 9.0 17.5 11.9 12.9 21.3 10.2 18.3 15.1 13.6 26.6 18.0 15.1 13.1 4.6 10.1 17.4 59.5 20.4 13.0 7.4 13.4 5.0 10.8 8.7 4.7 8.2 7.0 7.2 5.3 NUDT10 "DIPP3a, hDIPP3alpha" ENSG00000122824 "Nudix hydrolase 10" Q8NFP7 X 51332231-51337525 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 28.8;seminal vesicle: 36.3;testis: 27.2" "Cell line enhanced" "Detected in some" "AF22: 6.1;HAP1: 11.4;HEK 293: 8.4;NTERA-2: 20.9;SH-SY5Y: 4.6;U-2 OS: 10.5" "Group enriched" "Detected in many" 6 "glioma: 5.0;prostate cancer: 5.4;testis cancer: 7.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 2.1" "Low lineage specificity" "Detected in many" "HPA047027, HPA057684" Approved Approved Cytosol Cytosol "HPA047027: , HPA057684: " "unprognostic (2.61e-2)" "unprognostic (1.12e-2)" "unprognostic (7.40e-3)" "unprognostic (7.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.54e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.51e-3)" "unprognostic (1.80e-3)" "unprognostic (1.04e-2)" "unprognostic (1.12e-2)" "unprognostic (5.04e-5)" 1.0 2.3 9.3 1.4 10.7 1.8 1.4 6.0 13.1 4.4 2.0 0.9 28.8 1.1 5.5 18.3 1.7 3.4 2.0 0.9 4.9 13.6 3.1 1.9 0.7 0.9 5.3 8.0 19.2 0.6 0.5 4.5 0.5 6.2 17.9 1.3 0.8 1.0 36.3 0.5 1.0 1.2 4.9 1.9 3.1 1.1 27.2 1.2 0.0 0.8 0.0 0.9 2.8 2.9 0.8 0.1 0.0 0.7 2.1 1.0 0.3 0.0 0.0 6.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 11.4 0.5 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 20.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.1 0.0 0.8 1.0 0.0 0.1 0.3 0.0 0.6 0.0 2.1 0.5 0.0 0.0 0.3 9.3 10.7 6.0 11.7 4.9 13.6 5.3 8.0 6.2 1.2 NUDT11 "DIPP3b, FLJ10628, hDIPP3beta" ENSG00000196368 "Nudix hydrolase 11" Q96G61 X 51490011-51496596 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;testis: 35.5" "Cell line enhanced" "Detected in many" "HAP1: 33.1;NTERA-2: 20.6" "Cancer enhanced" "Detected in many" "testis cancer: 17.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 3.7;MAIT T-cell: 1.4;memory CD4 T-cell: 1.2;memory CD8 T-cell: 1.9;naive CD8 T-cell: 3.1;NK-cell: 1.9" "Group enriched" "Detected in many" 5 "NK-cells: 1.9;T-cells: 3.7" "HPA047027, HPA057684" Approved Approved Cytosol Cytosol "HPA047027: , HPA057684: " "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (8.21e-2)" "unprognostic (1.93e-3)" "unprognostic (6.61e-2)" "unprognostic (1.13e-3)" "unprognostic (5.52e-3)" "unprognostic (1.25e-1)" "unprognostic (2.25e-2)" "unprognostic (2.18e-1)" "unprognostic (8.41e-2)" "unprognostic (1.33e-1)" "unprognostic (7.80e-12)" "unprognostic (4.34e-4)" "unprognostic (1.17e-2)" "unprognostic (2.78e-1)" "unprognostic (3.94e-4)" 1.2 5.4 11.2 1.4 21.9 1.6 2.8 7.4 26.1 3.8 2.6 0.8 4.4 1.7 5.9 4.3 1.9 1.6 2.2 0.8 7.0 17.9 0.9 0.6 0.8 1.1 5.3 12.7 10.0 3.8 0.5 2.8 0.6 5.3 10.1 1.4 0.5 1.3 11.9 0.6 1.7 1.5 5.0 1.8 0.9 0.9 35.5 1.1 3.6 1.0 0.2 1.1 1.7 1.6 0.5 0.4 0.0 0.2 1.9 3.7 1.0 0.0 0.5 10.0 0.0 8.6 11.0 0.0 4.6 1.3 0.2 0.2 0.0 0.0 0.0 0.2 5.6 0.7 33.1 11.3 0.1 0.0 2.2 0.0 0.0 0.0 4.1 0.0 2.2 6.7 4.5 3.0 11.0 7.8 0.0 0.0 9.3 0.2 12.5 0.0 20.6 8.4 0.0 7.0 0.0 2.0 0.0 0.0 6.5 2.0 0.0 1.8 0.0 0.0 4.5 2.3 10.9 0.6 0.0 4.3 2.0 7.0 1.5 0.0 0.9 0.0 0.0 0.0 3.7 0.0 1.4 0.5 1.2 1.9 0.4 0.3 0.2 3.1 0.0 1.9 0.2 0.2 0.0 1.0 11.2 21.9 7.4 14.9 7.0 17.9 5.3 12.7 5.3 1.1 NUDT12 DKFZP761I172 ENSG00000112874 "Nudix hydrolase 12" Q9BQG2 5 103548855-103562793 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045449 Supported "HPA045449: " "unprognostic (1.94e-1)" "unprognostic (1.94e-2)" "unprognostic (3.27e-2)" "unprognostic (1.44e-1)" "unprognostic (7.53e-2)" "unprognostic (1.10e-1)" "unprognostic (2.61e-1)" "unprognostic (8.79e-2)" "unprognostic (9.16e-2)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (1.92e-1)" "prognostic favourable (2.86e-5)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (2.67e-1)" "unprognostic (5.92e-2)" 6.3 15.2 10.1 3.5 13.3 0.9 11.4 6.1 12.5 9.2 11.9 10.2 10.9 15.3 6.1 11.7 10.1 8.1 7.7 9.2 10.0 8.9 24.7 25.3 6.1 2.4 13.1 8.5 6.6 15.3 26.9 14.7 6.8 13.7 13.9 13.4 8.4 11.2 7.9 12.1 8.2 15.8 8.7 14.8 4.3 12.5 5.9 14.8 5.0 15.0 8.7 3.4 8.9 6.0 1.5 3.9 0.0 1.3 1.5 2.2 0.9 4.0 1.8 10.0 3.7 6.8 14.4 0.0 7.2 6.9 6.5 8.4 3.5 14.8 0.0 4.8 4.1 6.6 9.3 14.9 9.2 0.0 5.6 4.2 7.0 1.8 7.1 0.0 0.0 6.8 13.2 4.3 11.3 4.4 6.7 0.0 11.4 7.5 0.3 0.2 5.1 5.7 0.0 8.8 3.3 11.0 7.1 7.6 7.9 4.6 7.0 11.0 15.3 4.2 5.3 8.3 3.0 7.2 5.7 4.9 7.5 0.0 8.5 0.0 6.0 0.0 0.9 0.0 0.0 1.3 0.0 0.9 0.8 0.5 2.8 1.5 2.2 1.0 0.0 1.5 0.9 3.9 0.6 0.9 10.1 13.3 6.1 12.5 10.0 8.9 13.1 8.5 13.7 14.8 NUDT14 UGPP ENSG00000183828 "Nudix hydrolase 14" O95848 14 105172938-105181323 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046755, HPA058759" Approved Approved Nucleoli,Microtubules Microtubules Nucleoli "HPA046755: AB_10963433, HPA058759: " "unprognostic (1.05e-2)" "unprognostic (6.01e-2)" "unprognostic (1.89e-1)" "unprognostic (2.44e-1)" "unprognostic (1.91e-1)" "unprognostic (3.55e-1)" "unprognostic (1.05e-3)" "unprognostic (9.17e-3)" "unprognostic (2.02e-1)" "prognostic favourable (1.66e-4)" "unprognostic (3.16e-3)" "unprognostic (3.13e-1)" "prognostic favourable (1.18e-5)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (7.21e-3)" "unprognostic (2.38e-1)" 18.2 12.6 22.4 5.0 16.0 3.1 14.3 2.5 23.4 6.5 11.0 7.9 5.9 16.7 4.7 11.7 7.1 12.6 9.8 20.9 15.4 13.5 16.7 11.2 12.6 9.4 16.1 14.8 4.0 26.0 4.7 27.6 4.8 11.2 10.5 4.6 14.7 16.7 9.9 28.7 6.2 13.8 3.1 13.2 6.3 12.7 8.9 7.8 3.1 17.9 9.2 5.7 4.9 4.7 5.8 15.1 1.7 27.3 6.1 5.8 8.9 8.2 11.3 1.0 4.4 1.3 1.6 18.1 2.3 3.1 3.8 5.5 8.0 8.8 0.6 11.6 1.2 10.4 0.5 6.3 0.3 4.3 8.3 1.8 4.9 5.5 9.7 2.2 22.3 2.3 8.0 0.9 0.7 7.5 2.8 1.4 1.3 24.0 0.2 0.0 5.9 15.8 4.3 10.4 4.8 4.1 23.8 15.7 2.3 4.1 0.1 9.6 8.9 10.7 17.6 6.4 2.8 4.5 2.3 0.7 0.4 1.0 9.3 2.5 2.3 1.7 18.5 0.5 5.8 17.4 3.6 5.8 4.6 3.8 15.1 4.0 4.5 5.2 0.6 6.1 27.3 7.3 2.5 8.9 22.4 16.0 2.5 23.4 15.4 13.5 16.1 14.8 11.2 7.8 NUDT15 "FLJ10956, MTH2" ENSG00000136159 "Nudix hydrolase 15" Q9NV35 13 48037567-48047222 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA038968, HPA038969" Approved Supported Nucleoplasm Nucleoplasm "HPA038968: AB_10697402, HPA038969: " "unprognostic (9.48e-2)" "unprognostic (5.91e-3)" "unprognostic (2.64e-2)" "unprognostic (9.00e-3)" "unprognostic (4.99e-2)" "unprognostic (2.50e-3)" "unprognostic (2.29e-2)" "unprognostic (7.47e-3)" "prognostic unfavourable (1.25e-5)" "unprognostic (1.04e-1)" "unprognostic (8.50e-2)" "unprognostic (3.69e-1)" "unprognostic (4.63e-2)" "unprognostic (1.84e-3)" "unprognostic (3.35e-1)" "unprognostic (9.58e-2)" "unprognostic (8.93e-3)" 15.0 15.2 11.4 16.6 14.6 16.5 18.0 14.1 17.7 14.8 21.1 9.5 14.3 22.1 11.1 15.5 23.8 12.8 13.5 13.3 10.5 15.7 20.3 21.3 11.1 7.4 12.8 11.1 13.0 13.8 6.1 18.6 14.2 15.8 16.9 24.1 8.2 14.1 12.6 15.9 10.8 20.5 11.3 11.9 9.6 13.9 22.2 10.6 11.6 22.3 24.1 12.0 12.1 14.2 4.7 7.0 4.6 9.9 3.8 9.2 4.1 19.7 12.0 22.6 10.0 9.3 13.5 16.7 16.1 15.3 17.9 17.3 17.7 19.3 14.7 9.2 12.7 23.4 21.8 23.7 27.6 7.6 18.9 14.3 11.8 19.2 8.7 21.4 13.7 9.2 15.2 14.4 20.3 19.2 12.6 5.9 28.6 9.7 16.8 20.3 36.2 14.3 11.6 14.6 9.6 19.9 15.1 13.8 14.6 11.0 19.0 12.5 9.7 16.2 9.9 12.6 15.3 15.7 22.2 3.2 5.1 18.4 6.5 16.8 20.3 2.1 7.3 4.6 4.6 9.9 4.5 4.7 7.4 5.8 7.0 4.7 8.8 9.2 1.6 3.8 6.7 5.6 5.0 4.1 11.4 14.6 14.1 17.7 10.5 15.7 12.8 11.1 15.8 10.6 NUDT16 FLJ31265 ENSG00000198585 "Nudix hydrolase 16" Q96DE0 3 131381671-131388830 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 18.2;eosinophil: 18.8;intermediate monocyte: 21.9;myeloid DC: 13.6;neutrophil: 14.6;non-classical monocyte: 24.5" "Group enriched" "Detected in all" 4 "dendritic cells: 13.6;granulocytes: 18.8;monocytes: 24.5" "Low region specificity" "Detected in all" "HPA060452, HPA062492" Uncertain Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA060452: , HPA062492: " "unprognostic (4.85e-3)" "prognostic favourable (9.39e-5)" "unprognostic (3.19e-3)" "unprognostic (9.21e-2)" "unprognostic (2.49e-1)" "unprognostic (1.22e-2)" "unprognostic (9.96e-2)" "unprognostic (1.15e-1)" "unprognostic (5.16e-2)" "unprognostic (1.94e-1)" "unprognostic (1.77e-1)" "unprognostic (5.88e-2)" "prognostic favourable (1.05e-7)" "unprognostic (3.29e-1)" "unprognostic (1.62e-1)" "unprognostic (2.00e-2)" "unprognostic (9.44e-2)" 25.9 13.4 22.1 13.1 22.0 8.7 13.1 13.5 20.5 11.1 32.8 23.9 13.9 20.2 11.7 11.6 8.7 14.0 13.6 22.2 21.1 19.6 25.9 23.1 16.2 31.1 27.7 16.9 23.0 18.3 32.9 9.7 7.6 20.1 13.4 18.4 13.6 11.7 13.6 20.3 6.8 37.5 18.5 30.4 22.2 13.8 9.5 21.6 2.2 17.1 11.5 9.1 12.4 8.4 4.3 13.6 18.8 24.5 3.7 4.3 6.7 12.7 6.8 11.2 5.8 22.6 20.5 5.2 10.4 9.6 7.0 7.3 10.4 5.7 2.1 9.1 9.6 9.3 9.9 6.5 11.3 6.3 7.2 5.4 8.7 10.0 14.5 9.1 9.9 18.3 5.8 4.6 12.7 10.9 6.1 11.1 6.8 13.2 0.0 2.4 8.7 10.1 7.1 8.1 16.0 7.0 10.3 5.5 9.7 6.2 6.3 9.5 13.8 7.2 10.7 11.5 5.0 21.0 8.0 11.0 10.8 0.3 7.4 7.0 6.3 2.2 18.2 18.8 2.6 21.9 2.7 4.3 2.7 2.4 13.6 4.2 2.4 2.4 14.6 3.7 24.5 1.8 4.3 6.7 22.1 22.0 13.5 20.5 21.1 19.6 27.7 16.9 20.1 21.6 NUDT18 "FLJ22494, MTH3" ENSG00000275074 "Nudix hydrolase 18" Q6ZVK8 8 22106872-22109419 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028581, HPA030125" Approved Supported "Nucleoplasm,Golgi apparatus" Nucleoplasm "Golgi apparatus" "HPA028581: AB_10601381, HPA030125: " "unprognostic (9.90e-3)" "prognostic favourable (1.43e-4)" "unprognostic (4.88e-3)" "prognostic favourable (2.49e-6)" "unprognostic (1.29e-2)" "unprognostic (6.82e-3)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (5.30e-2)" "unprognostic (1.67e-1)" "prognostic favourable (2.47e-4)" "unprognostic (1.43e-1)" "prognostic favourable (8.30e-4)" "unprognostic (3.59e-3)" "unprognostic (1.05e-1)" "unprognostic (6.84e-2)" "unprognostic (2.32e-1)" 3.6 2.7 2.9 4.4 6.4 2.9 3.6 5.3 6.8 2.0 6.1 4.3 5.4 5.3 1.6 11.9 3.7 4.3 3.8 2.5 1.7 2.9 2.9 4.5 6.3 3.2 3.3 1.2 8.6 2.1 5.2 1.8 3.7 3.6 3.8 3.8 5.6 11.0 1.0 3.6 5.4 2.7 2.5 6.0 5.6 2.8 3.4 7.1 5.0 2.3 5.8 3.2 0.0 3.6 3.6 5.0 3.2 7.8 4.7 1.5 6.9 14.8 0.5 3.2 11.8 4.4 8.1 4.1 11.4 5.6 6.4 3.5 5.6 5.2 6.7 5.0 12.2 2.1 6.9 1.9 6.4 2.0 4.4 4.2 3.4 7.7 1.3 13.8 8.0 6.5 2.3 5.8 7.0 3.2 8.8 5.3 7.3 5.8 3.9 0.8 3.6 2.6 1.3 5.6 8.1 6.1 1.6 2.5 3.0 3.6 3.6 8.4 7.4 5.6 3.6 2.0 4.8 2.1 3.9 0.4 1.7 6.3 4.0 8.8 0.1 2.9 5.0 4.7 3.2 4.3 2.6 3.7 2.7 2.0 3.6 4.0 2.2 0.7 7.8 2.3 3.6 1.4 1.5 NUDT2 APAH1 ENSG00000164978 "Nudix hydrolase 2" P50583 9 34329506-34343713 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004684, HPA044903, HPA058623, HPA067639" Uncertain Enhanced Nucleoplasm Nucleoplasm "CAB004684: AB_425306, HPA044903: , HPA058623: , HPA067639: " "unprognostic (2.74e-3)" "unprognostic (2.58e-2)" "unprognostic (3.37e-1)" "unprognostic (2.05e-3)" "unprognostic (3.08e-1)" "unprognostic (2.39e-1)" "unprognostic (1.24e-1)" "unprognostic (6.55e-2)" "unprognostic (7.06e-2)" "unprognostic (3.05e-3)" "unprognostic (1.18e-2)" "unprognostic (2.80e-1)" "unprognostic (2.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.72e-1)" "unprognostic (1.23e-1)" "unprognostic (1.91e-1)" 12.0 18.0 21.6 9.6 21.9 10.2 20.6 14.0 25.5 14.9 14.9 26.0 15.4 12.8 15.7 30.2 14.5 20.5 12.3 16.0 17.3 18.6 10.7 17.5 11.2 12.2 19.5 19.0 28.3 20.9 12.0 19.0 14.1 20.5 16.5 15.3 15.7 16.1 13.0 30.8 13.9 10.1 14.7 20.7 11.3 13.0 8.6 19.1 18.6 3.8 13.2 13.8 14.4 12.1 16.6 15.8 14.3 12.2 14.3 22.2 11.2 23.6 9.8 12.7 4.5 8.8 16.2 9.2 11.4 25.9 13.3 13.9 6.7 11.2 6.6 9.5 14.2 10.4 11.5 28.2 13.5 24.6 10.3 14.2 18.4 12.5 25.4 10.9 5.8 16.3 18.2 17.1 32.2 27.3 4.0 26.9 19.3 14.7 11.3 10.3 7.8 28.1 14.7 7.9 16.6 13.0 7.7 2.6 10.4 18.5 7.0 10.7 5.7 11.8 17.6 11.5 10.3 7.5 11.9 6.1 9.8 11.6 14.3 10.5 14.2 14.3 12.2 9.7 11.7 10.3 16.7 16.6 19.2 15.2 15.8 15.0 22.2 19.6 4.5 14.3 10.7 14.7 19.7 11.2 21.6 21.9 14.0 25.5 17.3 18.6 19.5 19.0 20.5 19.1 NUDT22 MGC13045 ENSG00000149761 "Nudix hydrolase 22" Q9BRQ3 11 64225941-64230686 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039334, HPA053464" Approved Enhanced Nucleoplasm Nucleoplasm "HPA039334: AB_10795174, HPA053464: " "unprognostic (2.72e-1)" "unprognostic (3.77e-1)" "unprognostic (1.86e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-2)" "unprognostic (9.75e-2)" "unprognostic (1.73e-3)" "unprognostic (1.98e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-1)" "unprognostic (7.65e-2)" "unprognostic (6.61e-2)" "prognostic favourable (2.18e-6)" "unprognostic (1.76e-2)" "unprognostic (1.50e-1)" "unprognostic (1.71e-1)" "unprognostic (8.54e-2)" 9.2 16.8 8.1 16.0 9.2 14.3 9.8 7.3 12.8 9.2 24.2 9.1 30.9 29.6 9.1 16.9 17.8 9.0 16.7 23.4 8.3 7.0 21.1 30.1 10.2 15.9 10.5 8.4 7.9 26.4 13.8 12.2 14.7 8.6 12.3 8.5 9.0 28.6 35.2 24.9 12.9 23.7 11.4 7.8 20.5 18.5 7.8 7.7 19.5 15.4 15.7 19.6 13.5 9.4 30.0 49.1 20.0 33.9 19.2 25.0 20.1 14.5 9.3 2.3 9.7 3.6 4.4 8.9 6.1 6.4 4.4 4.1 6.0 12.4 6.9 16.3 6.1 15.2 1.4 9.7 0.6 8.8 3.9 9.3 6.8 6.3 10.7 6.0 15.4 6.7 7.3 4.7 5.0 7.2 4.5 7.6 5.2 21.8 8.3 11.1 3.7 19.7 10.2 3.9 25.6 7.7 8.1 5.4 8.6 5.4 20.6 24.5 21.0 6.8 6.7 7.5 7.1 23.5 5.2 28.5 11.3 4.3 25.7 7.0 8.7 13.8 28.7 20.0 23.0 33.9 20.5 25.3 20.3 22.4 29.1 30.0 18.0 19.6 17.3 19.2 31.8 49.1 25.0 20.1 8.1 9.2 7.3 12.8 8.3 7.0 10.5 8.4 8.6 7.7 NUDT3 DIPP ENSG00000272325 "Nudix hydrolase 3" O95989 6 34279679-34392674 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047027, HPA055953" Uncertain Approved Cytosol 110000 Cytosol "HPA047027: , HPA055953: " "unprognostic (2.42e-1)" "prognostic favourable (5.29e-4)" "unprognostic (9.63e-3)" "unprognostic (4.74e-3)" "unprognostic (3.60e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-3)" "unprognostic (4.21e-2)" "unprognostic (4.93e-3)" "unprognostic (1.08e-1)" "unprognostic (3.16e-1)" "unprognostic (4.63e-1)" "unprognostic (1.24e-2)" "unprognostic (3.28e-2)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (6.24e-2)" 10.5 11.4 38.8 9.3 28.6 8.8 12.6 33.4 40.0 15.4 11.4 16.8 10.3 7.7 11.4 25.9 10.8 15.2 8.5 16.9 33.8 30.0 15.3 10.1 11.2 10.5 29.4 25.6 17.4 9.1 27.9 9.3 8.9 26.1 11.4 9.7 11.2 9.4 15.6 50.7 11.2 8.0 11.2 20.3 13.0 8.4 7.3 21.3 5.4 21.3 8.7 12.1 8.6 9.9 4.5 6.4 12.4 5.9 2.1 3.9 2.6 5.4 4.0 10.7 21.0 7.2 12.2 4.7 3.9 6.7 4.1 3.0 4.8 3.8 19.5 5.4 7.1 4.6 6.1 10.7 7.7 7.2 7.7 21.5 5.6 10.3 7.1 20.2 11.2 10.9 10.0 5.0 9.4 11.8 21.3 7.1 6.6 5.7 14.0 23.7 6.9 4.0 12.2 8.9 20.3 9.4 11.4 15.2 16.9 8.8 12.5 15.9 12.5 14.5 12.9 8.3 3.0 7.2 8.6 6.1 14.0 14.3 5.0 20.7 12.9 1.9 5.8 12.4 3.4 5.9 3.9 3.4 3.4 3.2 6.4 4.5 3.2 3.7 4.1 2.1 5.8 3.2 2.4 2.6 38.8 28.6 33.4 40.0 33.8 30.0 29.4 25.6 26.1 21.3 NUDT4 "DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, KIAA0487" ENSG00000173598 "Nudix hydrolase 4" Q9NZJ9 12 93377883-93408146 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 140.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA017593, HPA047027, HPA057684" Approved Approved Cytosol Cytosol "HPA017593: AB_1854703, HPA047027: , HPA057684: " "unprognostic (1.44e-2)" "unprognostic (2.15e-1)" "unprognostic (4.40e-3)" "unprognostic (4.25e-1)" "unprognostic (3.08e-3)" "unprognostic (1.42e-1)" "unprognostic (8.12e-2)" "unprognostic (9.09e-3)" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (2.60e-2)" "unprognostic (1.96e-1)" "prognostic favourable (1.27e-4)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (5.01e-1)" "unprognostic (8.32e-3)" 17.2 29.7 14.1 14.7 9.5 37.4 20.4 7.0 29.0 15.2 14.7 6.7 17.5 6.5 13.6 24.8 13.7 12.8 40.0 140.7 12.4 12.4 47.9 11.2 11.3 10.9 9.4 13.7 41.9 21.1 16.1 11.9 19.2 13.9 27.1 16.9 25.1 65.2 14.8 40.3 8.1 12.7 13.8 12.6 9.2 13.1 10.6 6.3 14.6 25.5 22.4 8.9 19.6 32.9 6.0 4.1 13.6 3.6 7.6 6.6 2.5 5.8 5.1 9.2 10.3 34.3 14.2 11.6 16.4 13.1 9.4 7.0 47.4 14.7 8.2 3.6 13.1 7.4 25.8 8.3 14.5 12.6 5.4 30.9 4.4 24.1 33.1 16.1 7.5 30.8 27.8 9.7 21.8 53.6 31.4 11.6 10.8 6.0 14.9 15.4 14.5 12.1 12.6 8.2 8.9 11.4 42.7 7.4 9.6 13.3 26.2 36.9 19.0 21.0 20.3 8.1 4.7 12.1 10.4 6.5 8.1 12.2 4.2 12.7 24.7 8.2 2.8 13.6 3.9 3.6 6.6 6.0 5.8 3.9 2.6 4.7 6.2 5.8 2.4 7.6 2.9 4.1 5.2 2.5 14.1 9.5 7.0 29.0 12.4 12.4 9.4 13.7 13.9 6.3 NUDT5 "hYSAH1, YSA1H" ENSG00000165609 "Nudix hydrolase 5" Q9UKK9 10 12165325-12196144 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019827 Approved Approved Nucleoplasm,Vesicles,Centrosome 660000 Vesicles "Nucleoplasm, Centrosome" "HPA019827: AB_1854704" "unprognostic (2.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.77e-3)" "unprognostic (4.91e-2)" "unprognostic (2.54e-2)" "unprognostic (4.60e-2)" "unprognostic (1.32e-1)" "unprognostic (6.39e-3)" "unprognostic (2.06e-1)" "unprognostic (9.97e-2)" "prognostic unfavourable (7.14e-12)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (3.12e-2)" "unprognostic (3.68e-2)" 19.6 22.0 17.4 18.6 21.2 13.5 20.2 15.4 21.4 16.7 20.4 16.1 15.2 17.3 10.0 16.5 25.8 16.3 12.1 10.0 16.2 14.3 26.0 57.1 16.8 22.7 21.7 12.8 12.5 16.9 19.1 35.7 19.9 18.5 13.4 24.2 13.2 16.7 19.7 5.1 20.6 15.9 11.6 17.9 22.4 14.1 8.0 21.5 28.2 19.1 16.5 29.5 16.2 18.6 22.4 45.9 50.1 19.5 16.2 37.0 20.4 37.3 27.6 33.0 30.7 32.0 31.6 29.3 27.7 17.7 32.7 35.1 39.6 35.7 37.4 24.1 22.4 37.6 46.0 42.9 30.0 30.6 45.0 31.1 33.9 58.1 33.4 20.6 21.9 33.2 25.6 35.6 18.2 41.6 41.6 25.6 29.7 34.3 38.6 24.2 28.7 17.2 35.3 12.0 43.4 30.5 12.9 15.9 23.9 33.6 25.9 38.5 44.4 21.3 26.0 13.9 26.7 38.8 33.8 21.6 37.9 50.3 29.3 26.9 10.3 8.1 19.1 33.5 22.8 19.5 26.2 22.4 24.6 26.8 27.0 18.3 17.0 23.0 50.1 16.2 14.8 45.9 37.0 20.4 17.4 21.2 15.4 21.4 16.2 14.3 21.7 12.8 18.5 21.5 NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422582-87459454 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" 9000 "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: AB_10696790, HPA044866: , HPA078535: " "unprognostic (7.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.45e-2)" "prognostic favourable (7.43e-5)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-2)" "unprognostic (4.23e-1)" "prognostic favourable (8.00e-11)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-3)" 14.2 25.6 19.5 10.0 22.7 4.0 31.1 22.5 22.3 17.9 19.6 11.8 18.0 27.0 17.3 24.5 12.8 16.2 11.4 18.0 21.8 19.4 28.1 30.9 15.8 12.2 22.9 16.5 18.4 64.1 35.4 33.1 17.5 20.0 22.5 18.3 11.3 20.2 18.7 23.8 10.2 30.0 16.0 17.0 9.9 14.1 14.1 22.6 7.6 22.7 16.0 9.7 13.6 35.9 13.9 13.8 3.7 13.9 9.3 18.3 10.6 10.6 11.5 12.8 6.4 25.4 16.0 10.4 20.5 13.3 7.9 7.9 8.1 18.4 15.6 21.0 16.6 7.3 11.8 14.4 12.7 11.7 9.1 5.1 13.4 14.1 16.0 9.3 8.4 15.4 19.2 9.4 8.9 15.8 14.3 10.5 14.9 14.0 13.0 10.1 10.3 4.7 15.3 11.4 9.1 59.7 9.8 15.5 10.6 13.2 23.4 10.4 13.4 13.5 16.2 12.8 12.4 9.3 10.0 8.1 6.3 12.7 18.4 8.8 16.1 0.9 11.7 3.7 13.4 13.8 12.4 13.9 13.4 13.2 13.8 12.0 15.9 18.3 1.3 9.3 13.9 13.0 12.3 10.6 19.5 22.7 22.5 22.3 21.8 19.4 22.9 16.5 20.0 22.6 OCRL OCRL1 ENSG00000122126 "OCRL, inositol polyphosphate-5-phosphatase" Q01968 X 129539849-129592561 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" Hydrolase "Cataract, Ciliopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "non-classical monocyte: 6.6" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;monocytes: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012495 Approved Approved "Microtubules,Centriolar satellite,Cytosol" Cytosol "Microtubules, Centriolar satellite" "HPA012495: AB_1851804" "prognostic unfavourable (2.93e-5)" "unprognostic (3.17e-2)" "unprognostic (2.30e-1)" "unprognostic (6.34e-3)" "unprognostic (9.88e-2)" "unprognostic (1.35e-1)" "unprognostic (2.82e-2)" "unprognostic (2.68e-1)" "unprognostic (3.08e-3)" "unprognostic (2.56e-2)" "unprognostic (6.30e-3)" "unprognostic (1.74e-1)" "unprognostic (4.61e-3)" "unprognostic (4.10e-1)" "unprognostic (5.83e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" 12.1 20.5 10.7 6.0 18.2 5.3 10.8 13.4 23.1 12.7 13.4 10.1 28.8 9.1 15.8 19.7 13.3 12.8 13.8 8.6 13.0 20.5 10.9 11.3 8.6 6.0 12.9 15.1 33.0 12.4 37.3 20.3 13.2 17.8 21.7 14.1 15.3 8.5 27.7 11.4 9.6 9.8 21.5 8.0 6.3 11.4 23.2 6.4 4.3 19.0 5.6 4.1 18.0 9.2 0.4 2.4 0.3 6.6 0.0 0.7 0.7 9.6 11.2 9.2 10.4 16.4 13.6 9.0 14.9 11.9 15.4 14.3 7.5 7.1 0.8 25.7 12.6 6.1 17.0 11.3 16.1 0.0 11.5 3.0 10.1 7.5 12.2 3.0 0.3 11.4 15.0 15.1 15.1 11.4 4.0 7.4 16.0 12.7 2.2 4.2 3.3 16.7 2.2 9.6 5.8 8.8 10.1 11.3 14.3 7.0 10.0 7.8 7.2 5.3 9.6 12.6 5.8 13.1 14.8 2.1 1.6 2.0 8.8 11.1 9.9 0.0 2.1 0.0 0.2 2.4 0.7 0.3 0.1 0.1 2.4 0.4 0.6 0.2 0.3 0.0 6.6 0.9 0.1 0.7 10.7 18.2 13.4 23.1 13.0 20.5 12.9 15.1 17.8 6.4 OLAH "FLJ11106, SAST, THEDC1" ENSG00000152463 "Oleoyl-ACP hydrolase" Q9NV23 10 15032227-15073852 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "placenta: 61.3;testis: 24.0" "Cell line enhanced" "Detected in some" "HSkMC: 5.8;hTCEpi: 7.3;LHCN-M2: 5.6;SK-BR-3: 8.8;U-266/70: 4.9" "Group enriched" "Detected in some" 7 "testis cancer: 3.6;thyroid cancer: 0.8" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "neutrophil: 6.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.6" "HPA037947, HPA037948" Enhanced "HPA037947: AB_10795028, HPA037948: AB_10805352" "unprognostic (2.01e-1)" "unprognostic (6.12e-2)" "unprognostic (8.20e-3)" "unprognostic (4.04e-3)" "unprognostic (1.92e-1)" "unprognostic (8.09e-2)" "unprognostic (7.12e-2)" "unprognostic (5.12e-2)" "unprognostic (4.55e-1)" "unprognostic (3.74e-2)" "unprognostic (4.70e-1)" "unprognostic (1.69e-1)" "unprognostic (5.22e-10)" "unprognostic (4.55e-2)" "unprognostic (2.09e-1)" "unprognostic (5.11e-2)" "unprognostic (9.78e-2)" 1.0 1.1 0.2 0.2 0.7 1.2 5.2 0.3 0.7 0.8 0.5 0.3 0.1 0.0 0.2 0.4 2.7 1.4 1.1 0.8 0.2 0.2 0.8 0.4 1.9 4.3 0.9 0.1 0.2 0.1 0.1 1.5 61.3 0.4 0.1 0.0 0.3 3.0 0.1 0.5 0.4 0.3 0.1 0.5 8.0 0.2 24.0 0.3 0.2 1.2 0.1 0.3 0.3 1.1 0.5 1.1 6.6 0.4 1.0 0.6 0.1 0.2 0.6 0.6 0.5 0.3 1.1 2.2 0.4 0.4 0.2 0.1 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.7 0.4 0.2 0.3 0.4 0.0 0.9 0.0 0.6 5.8 7.3 0.9 0.1 0.7 0.5 0.3 5.6 0.0 0.5 0.7 0.7 0.4 0.7 1.3 1.7 0.0 0.0 0.0 0.4 0.3 8.8 0.1 0.2 0.5 1.0 0.1 2.9 1.3 0.1 4.9 1.6 0.4 2.7 0.5 0.0 1.4 0.4 0.4 0.4 0.2 0.3 0.2 0.6 0.2 0.2 0.5 0.3 0.3 6.6 1.0 0.2 1.1 0.4 0.1 0.2 0.7 0.3 0.3 0.2 0.2 0.9 0.1 0.4 0.3 OPA1 "FLJ12460, KIAA0567, MGM1, NPG, NTG" ENSG00000198836 "OPA1, mitochondrial dynamin like GTPase" O60313 3 193593144-193697823 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Sensory transduction, Vision" Hydrolase "Cardiomyopathy, Deafness, Disease mutation, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036926, HPA036927" Supported Supported Nucleoplasm,Mitochondria 13000 "Nucleoplasm, Mitochondria" "HPA036926: AB_10671247, HPA036927: " "unprognostic (2.10e-2)" "unprognostic (9.23e-3)" "unprognostic (7.98e-2)" "prognostic unfavourable (8.61e-4)" "unprognostic (1.62e-2)" "unprognostic (4.59e-2)" "unprognostic (2.24e-1)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (8.44e-5)" "unprognostic (3.48e-2)" "prognostic favourable (1.84e-4)" "unprognostic (2.92e-1)" "unprognostic (4.75e-1)" "unprognostic (4.50e-3)" "unprognostic (3.21e-1)" 17.0 19.7 18.2 13.5 31.7 25.9 15.9 20.2 30.9 13.9 21.8 11.1 12.6 20.0 15.2 11.8 18.8 11.8 12.8 43.9 23.0 19.4 21.8 24.1 10.7 15.3 19.0 22.4 13.2 13.4 20.9 15.6 13.8 28.0 15.5 20.5 9.1 15.7 20.8 38.4 14.6 17.3 16.5 17.0 13.1 16.7 7.6 10.8 18.0 16.8 18.4 14.2 16.5 13.6 8.3 8.8 8.2 17.6 5.0 7.5 5.9 25.9 8.3 8.5 9.3 7.5 11.9 9.0 12.6 11.6 13.9 13.6 20.3 8.8 17.3 27.3 11.8 16.9 14.8 14.3 24.6 20.8 12.0 29.9 7.4 10.1 11.7 24.5 13.8 13.2 12.8 13.4 19.0 11.7 12.6 17.0 13.8 20.5 9.5 13.6 11.9 27.9 12.5 18.6 18.5 10.4 16.2 18.5 11.2 18.9 21.1 13.4 27.7 19.4 11.7 12.9 9.8 13.8 26.5 15.3 17.8 33.8 14.2 19.7 12.9 8.2 8.1 7.7 7.2 9.3 6.6 8.3 6.8 6.8 8.8 6.3 6.9 7.3 3.2 5.0 17.6 4.6 7.5 5.9 18.2 31.7 20.2 30.9 23.0 19.4 19.0 22.4 28.0 10.8 OPLAH "5-Opase, OPLA" ENSG00000178814 "5-oxoprolinase, ATP-hydrolysing" O14841 8 144051266-144063965 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.3" "Cell line enhanced" "Detected in many" "AN3-CA: 22.2;BEWO: 13.9;Hep G2: 11.9;PC-3: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.0;intermediate monocyte: 1.0;neutrophil: 3.8" "Group enriched" "Detected in many" 9 "granulocytes: 3.8;monocytes: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026562, HPA028260, HPA052429" Uncertain Approved "Nucleoli fibrillar center" "Nucleoli fibrillar center" "HPA026562: AB_1854804, HPA028260: AB_10601383, HPA052429: " "unprognostic (7.89e-2)" "unprognostic (3.08e-2)" "unprognostic (1.69e-1)" "unprognostic (9.09e-2)" "unprognostic (2.21e-2)" "unprognostic (3.87e-3)" "unprognostic (2.04e-2)" "unprognostic (9.37e-2)" "unprognostic (2.90e-1)" "unprognostic (1.26e-1)" "unprognostic (6.82e-2)" "unprognostic (3.62e-1)" "prognostic favourable (1.53e-6)" "unprognostic (4.03e-3)" "unprognostic (4.33e-1)" "unprognostic (3.54e-2)" "unprognostic (8.24e-2)" 5.6 5.6 3.3 1.7 3.9 2.3 3.1 4.9 5.3 1.9 7.0 7.0 4.5 11.8 1.6 1.9 5.9 1.3 5.2 16.2 2.5 1.7 10.8 17.2 2.9 2.0 4.5 4.2 2.0 6.0 5.8 1.2 1.3 5.5 3.5 2.0 4.8 9.4 5.6 25.6 5.5 10.4 1.2 4.4 3.7 7.2 49.3 4.9 0.3 1.9 5.4 1.8 2.1 3.3 0.0 0.3 3.8 3.0 0.0 0.1 0.8 2.7 2.7 0.3 22.2 1.0 2.1 13.9 1.3 0.9 0.8 0.4 5.1 5.0 0.0 4.5 2.4 3.5 0.7 2.0 0.0 0.7 0.0 0.9 4.0 11.9 7.1 0.1 0.0 2.9 9.2 0.9 0.0 0.1 3.2 0.0 0.0 3.0 0.2 2.1 1.9 17.2 0.2 0.0 3.4 2.4 3.2 0.8 0.1 0.0 0.9 0.0 5.7 2.9 0.1 0.0 3.7 0.0 0.9 0.7 0.9 0.6 0.3 0.7 0.0 0.0 3.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 3.8 0.0 0.4 0.0 0.0 0.8 3.3 3.9 4.9 5.3 2.5 1.7 4.5 4.2 5.5 4.9 OTUB1 "FLJ20113, FLJ40710" ENSG00000167770 "OTU deubiquitinase, ubiquitin aldehyde binding 1" Q96FW1 11 63985853-64001811 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, DNA damage, DNA repair, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039176, CAB072836" Approved Supported Approved Nucleoplasm,Cytosol 630000 "Nucleoplasm, Cytosol" "CAB072836: , HPA039176: AB_10674980" "unprognostic (2.50e-1)" "unprognostic (5.70e-3)" "unprognostic (3.93e-2)" "unprognostic (1.63e-1)" "unprognostic (2.78e-1)" "prognostic unfavourable (3.05e-4)" "unprognostic (1.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.45e-1)" "unprognostic (1.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (6.76e-2)" "unprognostic (1.42e-1)" "unprognostic (4.84e-2)" "unprognostic (1.82e-1)" 19.8 24.7 41.9 24.1 61.6 32.6 20.8 41.8 101.9 24.3 25.0 31.9 22.3 24.7 21.9 23.6 37.8 34.5 21.6 31.6 46.9 37.8 27.2 27.6 23.0 31.9 33.1 45.4 23.4 23.0 26.0 21.6 30.7 60.4 23.8 24.1 24.2 30.4 27.7 26.7 36.9 26.0 23.1 26.7 25.7 23.9 22.1 21.2 27.8 29.9 24.5 32.8 27.1 22.9 46.0 60.8 56.1 71.3 44.8 64.5 78.2 30.5 55.2 30.5 26.9 20.6 22.8 23.4 18.4 27.4 41.0 30.3 37.0 29.3 16.3 35.0 29.5 38.2 39.3 45.8 25.5 18.8 30.5 27.1 33.1 46.8 28.9 26.9 29.8 24.2 29.8 31.3 20.0 38.6 18.9 18.5 27.5 62.8 29.3 35.6 35.7 26.3 24.1 11.9 27.8 42.6 44.7 23.1 33.3 20.8 32.0 33.6 49.6 23.8 27.9 21.9 21.3 29.3 24.1 21.8 13.7 23.3 28.3 17.5 20.9 55.1 56.3 54.3 53.1 71.3 41.4 46.0 49.1 48.6 60.8 41.9 38.4 42.6 56.1 44.8 60.9 42.1 64.5 78.2 41.9 61.6 41.8 101.9 46.9 37.8 33.1 45.4 60.4 21.2 OTUB2 "C14orf137, FLJ21916, MGC3102" ENSG00000089723 "OTU deubiquitinase, ubiquitin aldehyde binding 2" Q96DC9 14 94026329-94048930 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.5" "Cell line enhanced" "Detected in many" "Karpas-707: 18.2;RPTEC TERT1: 11.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 2.5;myeloid DC: 3.3;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 5 "dendritic cells: 3.3;monocytes: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002329 Enhanced "HPA002329: AB_1079537" "unprognostic (6.80e-3)" "unprognostic (1.39e-3)" "unprognostic (3.68e-3)" "unprognostic (4.82e-3)" "unprognostic (1.66e-1)" "unprognostic (2.20e-1)" "unprognostic (2.30e-3)" "unprognostic (1.18e-2)" "unprognostic (2.55e-1)" "unprognostic (3.09e-3)" "unprognostic (2.80e-2)" "unprognostic (1.16e-2)" "unprognostic (6.25e-3)" "unprognostic (1.15e-1)" "unprognostic (2.06e-2)" "unprognostic (1.02e-4)" "unprognostic (3.16e-1)" 2.3 1.3 2.6 0.5 3.3 0.4 1.7 1.0 5.3 2.9 1.0 0.8 1.9 0.7 1.7 1.4 5.2 1.2 0.8 0.4 3.3 1.1 1.7 1.5 0.7 0.6 0.8 1.3 1.6 1.7 4.6 1.0 6.2 1.4 1.2 1.6 0.8 1.9 0.5 0.3 9.5 0.7 0.6 1.0 0.6 1.0 34.5 0.5 0.0 0.6 1.0 2.6 1.7 2.0 0.2 3.3 0.2 2.5 0.0 0.5 0.9 1.3 3.6 2.4 2.3 1.0 0.8 2.8 0.5 0.3 1.5 2.1 0.8 5.9 0.3 2.3 0.6 0.3 3.2 1.7 1.2 0.8 1.4 0.1 0.4 3.7 1.3 0.0 0.6 0.6 2.2 0.5 0.9 1.6 0.1 18.2 0.7 1.2 0.1 0.4 0.7 3.1 0.1 0.2 1.0 11.4 1.7 1.8 1.3 0.7 0.8 1.9 6.4 0.8 1.6 1.0 2.9 0.7 1.0 3.0 2.1 0.0 1.8 0.9 1.4 0.0 2.1 0.0 0.3 2.5 0.0 0.2 0.4 0.5 3.3 0.0 0.2 0.0 0.2 0.0 1.9 0.1 0.2 0.9 2.6 3.3 1.0 5.3 3.3 1.1 0.8 1.3 1.4 0.5 OTUD1 "DUBA7, OTDC1" ENSG00000165312 "OTU deubiquitinase 1" Q5VV17 10 23439458-23442390 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.8;tongue: 61.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 24.7;HaCaT: 23.3;SiHa: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038503, HPA038504" Uncertain Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA038503: , HPA038504: AB_10672712" "unprognostic (1.84e-1)" "unprognostic (2.80e-2)" "unprognostic (1.96e-1)" "prognostic unfavourable (4.59e-4)" "unprognostic (1.56e-1)" "unprognostic (1.29e-2)" "unprognostic (3.18e-3)" "unprognostic (2.41e-1)" "unprognostic (7.77e-2)" "unprognostic (4.10e-2)" "unprognostic (1.80e-2)" "unprognostic (1.32e-1)" "prognostic favourable (6.61e-7)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-2)" 11.6 9.2 5.9 8.5 6.9 39.3 14.7 9.7 9.5 13.8 8.8 9.3 6.9 4.9 9.8 10.0 8.2 9.0 9.9 25.9 6.0 5.9 14.7 7.3 26.6 11.0 6.2 6.7 10.9 6.5 12.8 7.8 11.5 5.4 8.0 5.8 9.8 6.4 6.2 60.8 17.5 7.9 7.3 6.5 13.1 16.9 9.9 5.8 8.1 14.9 61.1 12.3 12.7 10.5 3.5 1.0 5.1 4.0 0.2 3.5 0.5 2.9 1.4 1.6 0.7 6.3 3.2 2.0 1.2 2.7 2.9 2.6 0.6 24.7 1.4 2.6 1.5 23.3 1.7 2.9 1.9 10.5 4.5 0.0 3.6 0.9 5.4 0.2 2.0 3.2 12.9 0.8 4.1 0.9 0.3 9.9 1.6 1.4 0.9 0.9 1.2 0.8 1.5 7.1 1.3 3.8 2.6 0.7 1.7 15.1 2.7 6.8 1.1 2.1 1.7 1.6 2.4 4.5 0.5 4.8 9.0 0.7 2.5 0.9 0.6 5.1 1.6 2.6 0.8 1.7 1.0 1.9 1.5 0.8 1.0 3.5 1.2 1.7 3.6 0.2 4.0 0.6 3.5 0.5 5.9 6.9 9.7 9.5 6.0 5.9 6.2 6.7 5.4 5.8 OTUD3 "DUBA4, KIAA0459" ENSG00000169914 "OTU deubiquitinase 3" Q5T2D3 1 19882513-19912945 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028543, HPA028544" Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" Cytosol "Nucleoplasm, Intermediate filaments" "HPA028543: AB_10599302, HPA028544: AB_10602277" "unprognostic (6.45e-3)" "unprognostic (9.26e-2)" "unprognostic (3.77e-1)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" "unprognostic (3.16e-3)" "unprognostic (1.70e-3)" "unprognostic (3.15e-3)" "unprognostic (4.99e-2)" "unprognostic (1.09e-1)" "unprognostic (8.81e-2)" "unprognostic (4.68e-2)" "unprognostic (1.08e-1)" "unprognostic (9.83e-2)" "unprognostic (1.94e-1)" "unprognostic (7.28e-2)" "unprognostic (2.21e-2)" 6.5 11.0 15.0 6.9 19.2 11.4 10.0 19.3 23.2 10.6 8.9 6.6 6.4 10.2 14.2 13.0 6.1 8.2 7.2 5.2 12.6 7.3 7.1 4.8 8.5 7.0 9.9 12.5 11.2 7.2 9.3 20.2 5.4 9.0 9.8 8.3 6.9 6.2 9.2 9.2 13.0 9.6 11.9 8.1 7.7 7.3 28.4 9.7 6.0 6.9 2.9 6.3 7.0 7.6 1.7 0.6 0.8 0.4 0.6 2.2 0.3 5.0 1.9 8.6 10.3 3.7 3.3 8.5 5.4 3.1 2.8 2.7 9.0 4.8 8.0 4.4 11.9 5.0 8.0 3.1 5.5 5.2 10.7 7.7 10.2 6.2 2.0 5.6 7.1 2.7 3.1 4.4 5.7 3.7 5.4 3.4 4.8 2.7 4.3 5.6 4.1 5.1 10.0 22.0 3.0 4.7 5.5 7.6 5.4 3.9 3.1 4.2 4.7 4.2 4.4 6.7 8.6 7.4 4.6 4.0 3.4 5.0 4.7 7.6 3.1 0.8 0.4 0.1 1.5 0.3 1.4 1.7 1.7 1.4 0.3 1.3 2.2 1.8 0.7 0.6 0.1 0.6 0.9 0.3 15.0 19.2 19.3 23.2 12.6 7.3 9.9 12.5 9.0 9.7 OTUD4 "DUBA6, HSHIN1, KIAA1046" ENSG00000164164 "OTU deubiquitinase 4" Q01804 4 145110838-145180161 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036623 Uncertain Supported Cytosol Cytosol "HPA036623: AB_10696780" "unprognostic (1.67e-1)" "unprognostic (4.18e-2)" "unprognostic (3.41e-2)" "unprognostic (1.95e-1)" "unprognostic (2.80e-1)" "unprognostic (4.06e-2)" "unprognostic (3.42e-2)" "unprognostic (2.66e-2)" "unprognostic (1.21e-1)" "unprognostic (1.74e-2)" "unprognostic (5.21e-3)" "unprognostic (2.03e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (2.62e-1)" 14.3 11.8 16.6 11.6 16.7 24.7 12.0 22.7 15.9 14.0 15.3 16.0 10.1 10.0 13.9 13.3 14.8 14.9 11.2 15.6 12.0 9.2 11.1 17.7 15.5 13.1 14.1 8.4 14.3 13.4 22.4 12.2 17.9 12.7 10.6 11.2 10.6 12.7 11.0 36.2 13.6 16.2 12.4 10.1 13.5 10.8 26.8 18.8 13.1 13.4 13.6 12.3 11.5 12.8 3.3 2.8 2.8 2.8 1.6 3.5 1.0 14.9 8.5 10.2 9.4 12.1 14.8 13.7 13.1 14.8 16.9 13.5 9.2 18.5 27.5 6.0 18.3 9.1 17.6 18.3 22.2 11.7 8.4 13.2 10.4 8.4 14.2 27.6 10.0 11.5 18.7 20.6 27.2 14.9 21.7 20.6 16.6 8.9 17.1 12.1 11.4 9.8 14.1 11.3 6.4 16.3 10.9 9.9 8.2 12.1 18.3 13.1 6.0 11.4 18.0 19.1 12.2 9.8 17.3 15.2 15.0 18.2 13.2 19.6 18.4 0.0 1.7 2.8 3.5 2.1 2.6 3.3 2.7 2.8 1.6 2.4 2.7 2.4 0.5 1.6 2.8 2.8 2.0 1.0 16.6 16.7 22.7 15.9 12.0 9.2 14.1 8.4 12.7 18.8 OTUD5 "DKFZp761A052, DUBA" ENSG00000068308 "OTU deubiquitinase 5" Q96G74 X 48922028-48958386 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "U-266/70: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017375 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoplasm, Nucleoli fibrillar center" "HPA017375: AB_1854844" "unprognostic (9.73e-2)" "prognostic favourable (9.57e-4)" "unprognostic (2.67e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (6.65e-2)" "unprognostic (2.33e-3)" "prognostic favourable (1.48e-4)" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "prognostic favourable (8.20e-4)" "unprognostic (1.32e-1)" "unprognostic (3.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (4.88e-2)" "unprognostic (5.05e-3)" 23.5 27.5 32.4 26.8 40.9 38.4 21.9 35.0 52.4 21.3 22.9 28.2 23.4 30.5 25.5 26.8 20.5 25.1 20.9 16.6 29.8 31.3 22.6 24.5 25.2 30.8 25.4 29.8 30.0 25.4 29.6 26.8 23.1 29.4 24.0 17.8 20.4 26.9 27.4 24.4 24.5 29.1 27.1 21.4 34.5 22.3 12.7 24.0 34.8 24.5 14.4 27.2 22.1 22.7 7.8 6.3 8.6 5.1 18.6 7.5 3.5 6.1 9.3 4.3 10.7 7.4 6.6 5.0 5.4 6.3 6.8 7.4 4.6 6.8 6.9 3.5 6.8 7.5 6.5 5.4 6.4 8.0 7.9 5.2 9.4 5.3 6.2 4.9 5.8 7.3 5.1 7.1 4.8 5.4 6.5 10.9 4.8 6.1 7.7 10.7 7.8 7.3 6.1 6.4 8.9 4.8 5.5 4.2 7.4 7.1 4.6 7.1 6.1 4.5 7.6 4.4 5.6 11.7 4.4 182.8 45.6 6.6 6.9 6.9 3.0 5.2 3.4 7.0 7.0 5.1 5.8 7.8 5.5 6.0 4.8 6.0 5.2 7.5 8.6 18.6 4.7 6.3 7.0 3.5 32.4 40.9 35.0 52.4 29.8 31.3 25.4 29.8 29.4 24.0 OTUD6A "DUBA2, FLJ25831, HSHIN6" ENSG00000189401 "OTU deubiquitinase 6A" Q7L8S5 X 70062491-70064179 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "blood: 3.8;testis: 13.6" "Cell line enhanced" "Detected in some" "MCF7: 2.0;U-2 OS: 1.9" "Cancer enriched" "Detected in single" 57 "testis cancer: 2.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA053304 Enhanced "HPA053304: AB_2682107" "unprognostic (1.58e-1)" 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 13.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.4 3.8 0.4 0.7 0.6 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.6 0.4 1.0 0.5 0.0 0.7 0.4 0.2 0.2 0.0 0.0 0.5 0.8 0.8 0.0 0.3 0.7 0.3 0.4 0.2 0.2 0.0 0.2 0.6 0.0 2.0 0.3 0.9 0.6 0.2 0.0 0.0 0.0 0.8 0.7 0.6 0.3 0.5 0.2 0.0 0.1 0.1 0.0 0.2 1.9 0.3 0.5 1.6 0.3 1.5 0.1 0.2 0.2 3.8 0.4 0.3 0.4 0.2 0.4 0.3 0.3 0.2 0.0 0.9 0.3 0.6 2.6 0.7 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OTUD6B "CGI-77, DUBA5" ENSG00000155100 "OTU domain containing 6B" Q8N6M0 8 91070196-91087095 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024046, HPA024503, HPA024772" Approved Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA024046: AB_10600925, HPA024503: AB_1854845, HPA024772: AB_1854846" "prognostic unfavourable (7.50e-4)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (4.78e-3)" "unprognostic (4.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.52e-2)" "unprognostic (1.16e-3)" "unprognostic (2.17e-1)" "unprognostic (5.51e-2)" "unprognostic (1.27e-2)" "unprognostic (8.61e-3)" "unprognostic (1.87e-2)" "unprognostic (1.96e-1)" "unprognostic (4.53e-1)" "unprognostic (8.78e-2)" "unprognostic (5.71e-2)" 11.4 11.3 14.6 14.1 18.2 8.9 13.2 13.8 19.6 12.3 11.3 9.9 10.3 9.2 12.1 9.0 13.2 9.1 8.6 14.0 14.9 13.7 11.0 10.5 10.0 13.8 18.5 15.5 12.5 9.9 11.2 14.4 14.9 16.2 11.6 11.3 6.0 9.5 14.8 35.3 11.2 9.1 12.4 19.9 11.3 8.8 11.9 17.4 13.9 11.8 11.0 11.9 11.9 14.0 7.2 12.9 8.8 7.8 7.8 6.8 2.9 16.0 9.3 8.3 6.2 3.7 2.8 8.7 12.7 4.8 11.9 7.7 7.9 10.1 17.1 6.2 6.7 5.5 17.2 10.4 18.5 13.7 10.5 23.2 9.6 6.0 8.0 11.8 12.3 4.7 5.0 9.6 22.7 9.6 23.2 10.7 10.1 8.7 19.8 7.7 4.5 18.4 8.9 8.0 15.2 9.3 11.6 2.0 7.5 1.2 28.3 12.3 14.5 5.7 9.8 7.1 10.7 10.8 12.1 10.7 20.4 25.0 10.4 14.8 13.6 8.8 6.5 4.3 5.9 7.8 6.8 7.2 4.8 5.7 8.1 6.8 6.7 5.9 0.9 7.8 5.8 12.9 3.6 2.9 14.6 18.2 13.8 19.6 14.9 13.7 18.5 15.5 16.2 17.4 OTUD7A "C15orf16, CEZANNE2, OTUD7" ENSG00000169918 "OTU deubiquitinase 7A" Q8TE49 15 31475398-31870789 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.4" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044554 Uncertain Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA044554: AB_10794895" "unprognostic (3.61e-2)" "unprognostic (1.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.25e-3)" "unprognostic (1.29e-1)" "unprognostic (1.03e-4)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (3.24e-3)" "unprognostic (1.34e-1)" "unprognostic (1.79e-11)" "unprognostic (6.78e-2)" "unprognostic (2.76e-1)" "unprognostic (8.27e-2)" "unprognostic (1.79e-1)" 2.6 2.0 12.4 1.7 13.9 5.9 1.5 13.2 17.0 1.8 3.4 16.0 0.0 1.5 1.9 1.9 1.9 2.0 2.3 2.1 10.0 4.6 2.3 1.0 1.5 3.5 20.4 7.1 2.0 2.5 4.6 1.7 0.9 10.5 1.2 3.1 0.7 1.6 2.0 1.8 3.2 2.1 2.9 9.1 2.2 2.3 8.2 17.4 0.0 2.3 0.0 2.4 1.9 1.3 0.1 3.2 0.3 1.4 0.1 0.7 0.4 3.6 4.1 4.5 6.0 0.4 1.3 3.2 2.5 1.3 3.9 1.9 2.5 3.2 2.9 2.2 0.9 4.6 4.8 2.0 3.2 5.9 6.6 3.7 8.3 2.0 0.3 4.0 5.7 0.0 0.2 3.8 4.3 3.5 6.0 5.4 1.8 2.9 3.1 3.9 2.0 2.0 5.6 3.0 1.4 1.6 3.9 10.9 6.0 3.4 3.0 1.0 2.5 4.3 2.3 5.3 5.2 3.0 6.2 3.3 2.4 3.0 2.9 5.8 4.5 0.0 0.4 0.3 0.6 0.5 0.3 0.0 0.3 0.7 0.2 0.1 0.2 0.2 0.0 0.1 1.4 3.2 0.0 0.4 12.4 13.9 13.2 13.8 10.0 4.6 20.4 7.1 10.5 17.4 OTUD7B "CEZANNE, ZA20D1" ENSG00000264522 "OTU deubiquitinase 7B" Q6GQQ9 1 149937812-150010676 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 4.7" "Group enriched" "Detected in many" 4 "granulocytes: 4.7;NK-cells: 1.4;T-cells: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027045 Supported Approved Nucleoplasm,Microtubules "Nucleoplasm, Microtubules" "HPA027045: AB_1854847" "unprognostic (2.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.90e-1)" "prognostic favourable (7.47e-4)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.23e-3)" "unprognostic (1.46e-2)" "prognostic favourable (5.09e-5)" "unprognostic (4.90e-2)" "unprognostic (7.72e-2)" "unprognostic (8.94e-2)" "unprognostic (3.37e-2)" "unprognostic (1.67e-2)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (1.58e-2)" 8.8 6.2 5.8 2.6 12.3 0.3 6.2 8.5 8.9 8.6 6.3 20.6 4.0 4.6 8.5 4.1 6.1 7.6 4.3 5.3 6.0 4.5 8.6 5.6 0.9 12.7 5.1 9.2 4.5 12.5 4.3 5.3 11.6 5.3 5.6 7.4 5.4 6.3 13.2 4.3 5.1 8.9 8.5 2.3 5.2 9.6 12.5 0.0 8.3 2.3 2.1 6.3 7.1 0.6 0.6 4.7 0.3 1.4 2.3 0.2 11.4 9.2 6.5 10.8 8.6 8.0 6.1 8.1 11.9 9.7 6.7 6.8 9.3 0.1 5.3 14.6 9.2 9.1 8.9 10.3 11.0 4.7 4.4 12.8 4.5 9.2 5.0 4.8 8.8 6.9 16.5 14.5 7.9 12.0 12.5 7.0 11.7 0.8 1.4 8.2 9.0 1.2 8.9 2.9 3.8 15.7 4.2 7.9 14.2 10.5 12.8 8.7 2.6 9.5 10.1 9.4 6.8 9.4 13.4 12.9 1.3 9.0 1.5 16.5 4.7 0.3 1.3 2.3 0.2 1.7 0.6 1.0 1.4 0.1 0.6 0.9 1.0 1.2 1.4 0.3 0.6 0.6 0.2 OTULIN "FAM105B, FLJ34884" ENSG00000154124 "OTU deubiquitinase with linear linkage specificity" Q96BN8 5 14664664-14699711 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051074 Uncertain Approved "Plasma membrane,Mitochondria" Mitochondria "Plasma membrane" "HPA051074: " "unprognostic (4.81e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (1.19e-2)" "unprognostic (7.48e-2)" "unprognostic (1.91e-2)" "unprognostic (7.94e-3)" "unprognostic (1.43e-1)" "unprognostic (2.48e-2)" "unprognostic (9.55e-2)" "unprognostic (1.02e-1)" "unprognostic (7.13e-2)" "prognostic unfavourable (2.59e-7)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (5.02e-2)" 10.0 7.4 5.9 22.6 7.8 32.3 8.4 7.2 6.6 8.2 9.3 8.3 8.9 10.7 9.5 7.7 13.8 6.1 10.8 15.5 6.7 4.9 8.5 19.5 11.1 16.0 9.6 2.8 9.1 12.2 7.5 9.8 11.8 7.0 11.1 7.0 7.7 10.6 10.8 16.5 18.1 11.7 8.1 10.5 12.5 7.1 11.5 7.4 15.0 7.8 9.7 19.3 8.5 15.8 3.4 2.9 3.1 3.0 1.0 4.6 0.9 6.3 7.4 7.4 8.4 6.9 7.2 8.2 6.4 4.5 9.1 6.9 9.9 4.7 11.4 12.6 4.1 7.2 9.2 8.4 6.3 19.7 7.6 8.2 23.5 5.3 5.9 7.8 14.1 4.1 10.3 7.5 6.4 7.7 8.1 18.3 6.5 3.9 7.7 6.8 4.5 7.8 11.9 6.7 4.6 6.0 6.6 3.4 5.5 22.8 5.1 4.9 5.6 9.0 7.1 11.9 13.4 8.9 8.4 8.3 12.5 13.0 6.8 14.9 6.1 0.4 2.0 3.1 1.0 2.2 3.0 0.9 2.5 3.4 2.9 3.4 1.8 3.9 2.2 1.0 3.0 2.5 4.6 0.9 5.9 7.8 7.2 6.6 6.7 4.9 9.6 2.8 7.0 7.4 PADI1 "HPAD10, PAD1, PDI, PDI1" ENSG00000142623 "Peptidyl arginine deiminase 1" Q9ULC6 1 17205126-17246005 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 48.7;lymphoid tissue: 60.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.3;EFO-21: 4.5;HaCaT: 2.8;LHCN-M2: 3.6;RPTEC TERT1: 4.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory region: 0.5" "Low region specificity" "Detected in some" HPA062294 Enhanced Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA062294: " "unprognostic (9.30e-2)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.40e-1)" "unprognostic (5.22e-2)" "unprognostic (7.27e-2)" "unprognostic (3.84e-1)" "unprognostic (3.37e-2)" "unprognostic (1.41e-1)" "unprognostic (7.75e-2)" "unprognostic (1.01e-3)" "unprognostic (3.64e-2)" "prognostic unfavourable (8.34e-11)" "unprognostic (2.00e-1)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.3 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.1 0.0 4.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.1 60.2 1.3 6.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.2 0.0 0.1 9.3 0.0 4.5 0.4 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119435 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 76.7;skeletal muscle: 126.4" "Cell line enhanced" "Detected in some" "A549: 6.8;RPTEC TERT1: 19.9;SK-BR-3: 30.4;T-47d: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 15.1;neutrophil: 37.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced "HPA047735: " "unprognostic (2.61e-2)" "unprognostic (3.60e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (3.74e-3)" "unprognostic (2.78e-3)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-3)" 2.1 1.4 16.2 5.0 25.1 10.9 19.2 3.3 25.6 2.7 41.4 76.7 1.3 1.6 1.4 1.3 3.8 2.3 1.8 1.1 21.9 15.6 5.5 1.3 2.2 1.4 36.8 13.6 1.1 1.7 1.3 1.5 1.6 45.6 2.3 43.4 4.6 21.1 1.8 126.4 2.8 3.6 3.9 69.6 4.2 2.1 1.3 26.0 0.0 1.2 14.8 1.6 2.1 0.7 0.0 4.2 37.2 5.1 0.0 0.0 1.7 0.0 6.8 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 2.9 0.1 0.9 0.3 0.9 0.2 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 2.2 0.3 0.8 0.9 0.0 0.0 0.0 0.2 19.9 0.0 1.2 0.1 0.0 30.4 0.0 8.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.4 5.1 15.1 0.0 0.3 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 37.2 0.0 0.1 0.1 0.0 1.7 16.2 25.1 3.3 22.0 21.9 15.6 36.8 13.6 45.6 26.0 PADI3 PDI3 ENSG00000142619 "Peptidyl arginine deiminase 3" Q9ULW8 1 17249098-17284233 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 10.5;smooth muscle: 9.4;urinary bladder: 28.0" "Cell line enhanced" "Detected in some" "EFO-21: 13.2;RT4: 15.8;T-47d: 11.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 48.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043739 Uncertain Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA043739: AB_10959466" "unprognostic (4.47e-2)" "unprognostic (9.32e-2)" "unprognostic (1.50e-1)" "prognostic unfavourable (3.22e-4)" "unprognostic (1.05e-3)" "unprognostic (6.66e-2)" "unprognostic (3.10e-3)" "unprognostic (5.88e-2)" "unprognostic (2.06e-4)" "unprognostic (1.03e-1)" "unprognostic (3.47e-4)" "unprognostic (1.76e-1)" "prognostic unfavourable (1.55e-11)" "unprognostic (2.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.64e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.1 0.0 0.0 3.2 10.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.6 6.4 0.0 2.3 0.0 9.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 28.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 13.2 0.0 0.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 15.8 0.0 0.0 0.0 2.3 0.1 11.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PADI4 "PAD, PADI5, PDI4, PDI5" ENSG00000159339 "Peptidyl arginine deiminase 4" Q9UM07 1 17308195-17364004 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood: 48.2;bone marrow: 54.8;lymphoid tissue: 24.2" "Cell line enhanced" "Detected in some" "BEWO: 1.7;HEL: 4.1;NB-4: 1.6;RPMI-8226: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "basophil: 17.0;classical monocyte: 18.6;eosinophil: 24.6;neutrophil: 48.2" "Group enriched" "Detected in many" 9 "granulocytes: 48.2;monocytes: 18.6" "Not detected" "Not detected" "HPA017007, HPA042825" Enhanced 12000 "HPA017007: AB_1854921, HPA042825: AB_2678189" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (1.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-2)" "unprognostic (8.49e-2)" "unprognostic (5.22e-2)" "unprognostic (8.55e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" 1.2 0.2 0.3 0.5 0.2 54.8 0.2 0.1 0.8 0.2 0.2 0.5 0.0 0.2 0.2 0.1 0.4 0.9 0.4 9.8 0.6 0.1 0.3 1.2 9.7 5.2 1.8 0.0 0.9 0.3 0.1 0.6 4.1 0.6 0.1 0.2 0.9 0.5 0.1 0.2 0.2 0.2 0.4 0.2 24.2 0.3 1.0 0.3 2.6 0.6 0.2 0.2 0.4 7.5 0.4 3.6 48.2 18.6 1.1 1.2 8.1 0.2 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 4.1 0.1 0.4 0.0 0.4 0.5 0.0 0.5 0.1 0.0 0.1 0.6 0.2 0.0 0.0 0.0 1.6 0.2 0.2 0.2 0.0 4.8 0.0 0.3 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.1 0.0 0.2 0.5 0.1 17.0 18.6 24.6 0.1 1.4 0.0 0.2 0.1 0.2 3.6 0.4 0.7 1.2 48.2 1.1 0.4 1.6 0.1 8.1 0.3 0.2 0.1 0.8 0.6 0.1 1.8 0.0 0.6 0.3 PADI6 ENSG00000276747 "Peptidyl arginine deiminase 6" Q6TGC4 1 17372196-17401699 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "blood: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in single" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (3.02e-2)" "unprognostic (6.56e-2)" "unprognostic (1.23e-1)" 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 3.5 0.0 0.8 0.0 1.9 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 1.9 0.1 0.0 0.0 0.2 1.1 3.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 PAFAH1B2 ENSG00000168092 "Platelet activating factor acetylhydrolase 1b catalytic subunit 2" P68402 11 117144267-117176894 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051836 Approved Supported "Nucleoli,Plasma membrane,Cytosol" 1600000 Cytosol "Nucleoli, Plasma membrane" "HPA051836: " "unprognostic (1.08e-2)" "unprognostic (3.14e-2)" "unprognostic (2.07e-2)" "unprognostic (3.88e-2)" "unprognostic (9.94e-2)" "unprognostic (1.21e-3)" "prognostic unfavourable (9.44e-4)" "prognostic unfavourable (3.07e-4)" "unprognostic (1.01e-1)" "prognostic favourable (4.25e-4)" "prognostic unfavourable (7.79e-5)" "unprognostic (8.18e-2)" "unprognostic (1.11e-2)" "unprognostic (9.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" 21.5 34.1 30.6 19.2 29.7 33.5 32.3 43.5 41.3 21.6 20.2 33.3 12.7 21.1 23.4 22.8 23.3 20.8 19.3 26.2 31.9 36.8 24.6 22.5 20.5 17.7 39.3 31.6 23.6 23.0 23.1 24.2 26.9 39.6 22.2 19.6 17.3 19.3 17.4 14.1 20.8 18.0 19.9 51.6 18.3 21.4 29.9 26.3 15.1 30.9 10.8 20.4 25.9 20.3 26.8 21.6 36.8 35.7 18.9 31.4 26.9 14.8 17.0 19.7 28.3 22.0 15.4 15.3 25.0 21.9 13.9 12.7 31.0 32.8 16.1 35.9 29.9 23.9 28.5 32.3 18.4 14.3 11.0 41.3 15.6 19.9 19.7 14.2 15.8 17.0 25.6 27.8 35.1 22.8 21.9 12.3 21.3 9.5 13.7 21.0 18.0 13.4 15.4 22.3 17.6 21.3 23.3 21.9 29.1 28.8 21.8 9.5 24.3 12.3 36.4 25.5 16.9 12.4 17.7 3.9 5.9 21.6 10.3 27.4 21.4 32.1 30.8 26.7 24.2 33.3 28.2 26.8 28.0 25.3 21.6 25.4 29.3 31.4 36.8 18.9 35.7 15.8 19.5 26.9 30.6 29.7 43.5 37.8 31.9 36.8 39.3 31.6 39.6 26.3 PAFAH1B3 ENSG00000079462 "Platelet activating factor acetylhydrolase 1b catalytic subunit 3" Q15102 19 42297033-42303546 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035639 Uncertain Approved "Intermediate filaments" 370000 "Intermediate filaments" "HPA035639: AB_10670163" "unprognostic (3.19e-1)" "unprognostic (5.38e-3)" "unprognostic (1.13e-1)" "unprognostic (5.99e-2)" "unprognostic (1.83e-1)" "unprognostic (2.09e-2)" "prognostic unfavourable (8.74e-4)" "unprognostic (1.73e-1)" "unprognostic (2.67e-1)" "unprognostic (6.36e-2)" "unprognostic (2.37e-1)" "unprognostic (7.67e-2)" "prognostic unfavourable (2.07e-4)" "unprognostic (2.68e-1)" "unprognostic (3.21e-2)" "unprognostic (4.56e-2)" "unprognostic (6.80e-3)" 4.5 12.8 23.8 10.4 23.2 20.7 12.2 36.4 24.9 17.2 14.6 7.8 8.0 10.9 10.1 11.9 15.5 13.5 9.6 4.6 15.4 25.7 11.7 5.6 5.8 13.6 13.9 13.1 15.4 11.9 8.3 11.8 5.8 12.4 10.3 10.7 11.2 9.8 6.1 10.8 10.6 11.2 6.6 11.7 9.5 11.3 16.3 11.3 37.4 7.8 13.8 15.4 14.6 10.9 19.6 24.6 8.7 13.6 7.8 27.4 10.5 29.4 54.0 33.7 36.0 0.7 1.8 10.4 7.4 10.3 24.4 25.3 17.9 24.8 18.2 9.7 9.0 10.0 15.3 19.5 10.2 27.5 20.9 22.0 14.5 24.0 5.2 13.9 24.5 5.3 9.0 14.9 7.0 10.8 15.5 21.7 17.7 43.0 31.1 10.9 18.7 0.0 23.1 12.9 16.2 19.8 31.1 38.8 30.4 11.8 23.5 12.4 29.3 16.0 5.8 20.3 27.4 1.8 20.0 10.4 21.4 15.5 11.3 22.6 17.8 8.7 13.6 7.2 12.1 10.7 16.1 19.6 17.3 13.9 24.6 18.4 23.0 16.0 1.8 7.8 5.4 13.6 27.4 10.5 23.8 23.2 36.4 24.9 15.4 25.7 13.9 13.1 12.4 11.3 PAFAH2 HSD-PLA2 ENSG00000158006 "Platelet activating factor acetylhydrolase 2" Q99487 1 25959767-25998157 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 33.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018157 Approved "HPA018157: AB_1854928" "unprognostic (9.89e-2)" "unprognostic (2.60e-1)" "unprognostic (3.63e-3)" "prognostic favourable (3.28e-6)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (4.46e-2)" "unprognostic (2.62e-1)" "prognostic favourable (0.00e+0)" "unprognostic (8.15e-2)" "unprognostic (8.17e-2)" "unprognostic (1.59e-2)" "unprognostic (7.27e-2)" 6.5 8.8 8.9 6.3 11.0 4.1 7.0 10.7 9.0 7.0 12.3 11.9 7.8 13.2 5.7 7.7 8.7 6.4 10.1 6.7 8.0 4.5 15.5 20.9 6.3 5.5 10.7 5.1 4.7 34.7 14.8 13.6 7.8 9.8 6.8 13.0 9.6 9.0 5.0 19.3 9.5 25.3 5.2 9.8 7.9 11.6 8.4 11.1 4.4 13.6 6.3 11.4 6.5 6.3 2.4 18.9 28.0 3.3 8.3 12.3 3.9 5.2 6.7 4.3 4.8 8.9 7.1 8.8 6.0 3.1 5.5 3.7 2.7 11.3 2.3 7.5 3.5 4.7 6.4 5.8 7.1 4.8 3.8 3.9 2.9 5.3 5.4 2.0 33.7 4.6 13.3 8.4 5.6 5.2 5.3 4.5 7.3 2.3 6.2 1.9 8.5 3.7 5.2 4.0 5.3 8.7 1.9 5.1 4.4 3.6 4.8 11.0 8.1 3.6 4.8 3.8 4.8 7.9 4.7 8.4 10.8 3.0 8.1 8.1 12.7 12.7 3.3 28.0 12.3 3.1 7.8 1.8 4.3 7.9 2.4 2.4 5.6 7.9 3.0 8.3 1.1 18.9 4.3 3.9 8.9 11.0 10.7 9.0 8.0 4.5 10.7 5.1 9.8 11.1 PAN2 "hPAN2, KIAA0710, USP52" ENSG00000135473 "PAN2 poly(A) specific ribonuclease subunit" Q504Q3 12 56316223-56334053 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.43e-1)" "unprognostic (3.78e-1)" "unprognostic (1.21e-2)" "unprognostic (2.55e-1)" "unprognostic (1.67e-1)" "unprognostic (9.10e-3)" "unprognostic (1.03e-1)" "unprognostic (7.28e-2)" "unprognostic (7.35e-3)" "unprognostic (3.80e-1)" "unprognostic (1.74e-3)" "unprognostic (4.23e-3)" "prognostic unfavourable (2.77e-4)" "unprognostic (4.19e-1)" "unprognostic (3.87e-1)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" 8.1 13.4 12.8 7.1 17.7 7.4 9.9 21.7 17.6 9.6 9.5 16.1 16.4 11.0 11.2 17.6 7.4 11.3 7.8 9.8 13.9 5.1 9.7 17.6 8.7 9.0 19.7 7.0 17.8 12.9 24.3 30.7 9.2 14.6 9.1 9.6 12.6 10.0 14.1 9.1 9.4 10.7 8.8 16.4 10.6 10.5 18.2 19.4 15.3 20.2 4.8 11.0 11.0 9.2 3.1 7.6 3.9 8.1 3.8 5.2 3.4 2.9 4.5 11.1 3.6 9.8 11.1 7.3 2.3 3.1 5.1 2.4 2.7 5.9 8.2 8.9 4.4 6.2 13.1 8.6 2.9 3.6 6.4 10.4 4.3 2.6 8.6 2.3 5.6 10.3 11.7 5.4 16.0 3.8 7.0 20.5 3.0 6.4 7.7 5.8 3.7 3.0 6.7 7.9 14.7 5.0 2.4 8.8 8.0 4.4 5.6 5.6 7.3 4.5 1.6 5.3 5.2 2.4 2.0 17.3 6.8 5.3 6.3 4.8 4.4 3.9 5.8 2.3 2.4 8.1 3.7 3.1 1.9 3.5 7.6 2.7 4.1 5.2 0.4 3.8 3.8 2.9 3.0 3.4 12.8 17.7 21.7 17.6 13.9 5.1 19.7 7.0 14.6 19.4 PAPPA "ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1" ENSG00000182752 "Pappalysin 1" Q13219 9 116153804-116402322 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 86 "placenta: 484.6" "Cell line enhanced" "Detected in some" "ASC diff: 19.0;ASC TERT1: 14.5;HSkMC: 52.2;U-138 MG: 13.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "midbrain: 10.4;olfactory region: 4.1;pons and medulla: 8.3;thalamus: 4.8" "HPA001667, CAB016724" Enhanced "Secreted in female reproductive system" 41000 "CAB016724: , HPA001667: AB_1854960" "unprognostic (3.25e-1)" "unprognostic (6.18e-6)" "unprognostic (2.47e-1)" "unprognostic (6.49e-2)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (5.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.87e-2)" "unprognostic (6.87e-3)" "unprognostic (8.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.37e-3)" "unprognostic (2.48e-1)" "unprognostic (4.01e-1)" "unprognostic (1.02e-3)" 4.8 2.3 0.5 1.0 0.5 0.0 0.8 0.4 0.6 3.6 2.4 0.6 1.0 0.1 3.5 1.0 3.6 2.0 1.1 3.7 0.4 0.0 4.3 0.5 2.4 0.7 0.4 0.4 1.4 0.7 5.6 0.7 484.6 0.7 1.4 0.9 0.9 0.5 1.2 0.5 1.1 0.9 2.4 0.6 0.6 1.0 0.8 0.5 0.4 1.3 1.0 1.0 2.3 3.4 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 5.4 8.3 0.0 19.0 14.5 0.0 4.4 7.8 1.2 2.1 0.0 0.0 0.0 0.0 3.1 0.6 0.0 0.0 5.9 0.0 0.0 0.9 4.5 0.0 9.2 0.0 0.0 52.2 0.0 6.1 0.7 0.0 0.2 0.0 1.4 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 10.5 13.6 0.7 0.3 0.5 0.0 0.0 0.0 9.7 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.4 0.6 0.4 0.0 0.4 0.4 0.7 0.5 PARG ENSG00000227345 "Poly(ADP-ribose) glycohydrolase" Q86W56 10 49818279-49970203 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021819, HPA053007" Enhanced Supported Nucleoplasm,Vesicles,Cytosol Nucleoplasm "Vesicles, Cytosol" "HPA021819: AB_1854974, HPA053007: " "unprognostic (5.77e-3)" "unprognostic (6.74e-2)" "unprognostic (3.06e-2)" "unprognostic (9.90e-2)" "unprognostic (1.22e-2)" "unprognostic (1.33e-1)" "prognostic unfavourable (5.57e-5)" "unprognostic (1.21e-1)" "unprognostic (3.97e-1)" "unprognostic (8.34e-2)" "unprognostic (1.47e-1)" "unprognostic (4.06e-2)" "unprognostic (5.20e-3)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (8.54e-2)" "unprognostic (1.13e-1)" 4.0 5.6 4.3 4.2 5.4 1.4 5.3 7.8 6.3 4.8 5.1 6.7 4.9 3.0 6.2 4.3 3.6 6.6 4.6 5.9 9.2 5.2 3.5 5.8 4.5 4.7 3.5 8.1 4.7 5.8 4.9 6.1 4.7 5.1 8.1 6.7 5.1 4.7 4.0 5.9 4.7 5.8 4.9 6.9 4.4 4.8 6.9 7.0 12.5 7.7 8.3 9.4 5.5 12.7 10.6 18.7 13.7 9.0 11.2 13.7 12.7 14.0 14.8 14.2 8.5 11.9 9.6 8.3 10.8 14.5 15.7 8.0 16.0 14.7 14.6 9.8 8.7 9.3 10.2 14.1 8.2 7.2 15.5 12.4 20.5 9.0 16.6 8.5 11.1 7.1 15.6 12.7 18.4 24.3 18.6 21.2 11.1 12.0 8.2 12.9 16.3 10.3 16.4 13.3 18.9 7.9 9.1 9.3 11.3 9.6 14.2 9.4 14.1 20.5 15.9 15.0 6.7 12.5 6.2 3.0 5.2 5.5 7.9 6.9 7.1 6.7 7.0 6.9 9.4 9.1 3.0 8.3 7.7 5.4 5.5 5.5 PARK7 "DJ-1, DJ1, GATD2" ENSG00000116288 "Parkinsonism associated deglycase" Q99497 1 7954291-7985505 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Fertilization, Inflammatory response, Stress response" "Chaperone, Hydrolase, Protease, RNA-binding" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004190, CAB005870" Supported Supported Nucleoplasm,Cytosol 69000000 "Nucleoplasm, Cytosol" "CAB005870: AB_444361, HPA004190: AB_1079566" "unprognostic (6.88e-3)" "unprognostic (7.50e-2)" "unprognostic (3.48e-2)" "unprognostic (1.16e-2)" "unprognostic (4.08e-2)" "unprognostic (5.68e-2)" "unprognostic (7.45e-2)" "unprognostic (9.63e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-3)" "unprognostic (8.17e-2)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (7.43e-2)" 44.6 67.9 69.3 38.1 64.9 33.7 45.4 57.2 62.7 34.0 36.4 33.4 43.2 27.3 35.8 56.6 40.9 39.0 41.6 71.7 56.9 57.2 60.5 77.1 28.6 46.1 61.6 57.2 45.9 60.4 66.6 48.4 44.6 41.2 44.7 39.5 38.6 46.5 39.4 128.7 19.8 27.5 48.1 52.5 37.5 37.2 38.2 32.2 38.8 71.6 43.3 46.5 41.3 43.4 49.5 141.8 38.8 61.0 52.8 87.2 90.6 68.2 61.5 61.3 70.4 66.0 63.5 30.1 63.6 59.6 62.6 50.6 56.0 74.8 84.7 71.9 68.2 49.0 66.1 85.0 81.4 75.3 71.4 91.0 91.9 83.1 57.0 86.8 56.1 59.8 36.3 63.8 76.7 65.6 88.3 63.1 86.8 63.9 60.4 110.3 50.0 63.5 46.5 82.3 116.1 98.2 35.1 71.7 60.2 63.6 98.3 99.2 54.8 64.7 62.1 57.8 46.1 53.3 69.7 61.3 98.3 120.5 76.2 132.9 81.8 22.7 61.0 38.8 52.6 55.4 49.7 49.5 52.7 62.2 73.9 38.6 45.6 52.4 21.0 52.8 44.1 141.8 87.2 90.6 69.3 64.9 57.2 62.7 56.9 57.2 61.6 57.2 41.2 32.2 PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA019545 Approved Approved Mitochondria Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favourable (9.11e-5)" 24.2 20.6 26.2 19.2 30.1 21.2 30.4 22.1 29.6 22.7 29.0 24.4 19.4 21.5 20.2 43.8 21.4 19.6 21.2 30.9 23.1 23.4 27.0 26.7 20.3 26.5 28.4 20.3 20.3 47.5 22.0 20.6 18.5 19.5 22.1 31.3 25.9 35.1 33.4 41.2 22.3 27.0 38.1 19.4 22.3 24.5 22.2 18.9 22.1 20.7 25.4 24.3 23.2 18.2 21.5 45.4 44.3 50.0 21.5 25.9 35.4 32.1 15.3 11.3 9.6 11.0 12.7 23.5 12.1 16.4 23.3 18.3 46.9 16.8 14.3 26.9 15.3 14.3 18.0 18.6 26.3 20.4 22.1 21.6 10.2 25.6 16.6 21.4 18.3 17.2 23.9 16.3 20.0 16.5 12.2 13.4 19.1 34.8 40.9 52.5 30.3 15.7 18.1 22.1 26.0 21.7 26.9 11.4 16.3 14.4 46.4 29.5 47.7 40.7 9.7 8.7 18.9 17.9 30.7 26.9 18.2 33.0 16.6 21.9 10.4 27.6 50.0 44.3 19.0 35.4 21.7 21.5 21.6 22.1 45.4 19.9 25.9 21.1 14.5 21.5 26.2 27.0 24.4 35.4 26.2 30.1 22.1 29.6 23.1 23.4 28.4 20.3 19.5 18.9 PARN DAN ENSG00000140694 "Poly(A)-specific ribonuclease" O95453 16 14435701-14632728 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease mutation, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006314, CAB011673, HPA012010" Supported Supported "Nuclear speckles" "Nuclear speckles" "CAB011673: AB_778216, HPA006314: AB_1079567, HPA012010: AB_1854976" "unprognostic (2.54e-1)" "unprognostic (3.43e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-1)" "unprognostic (2.28e-1)" "prognostic unfavourable (4.64e-4)" "unprognostic (2.99e-3)" "unprognostic (5.07e-2)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (2.16e-3)" "unprognostic (1.75e-1)" "unprognostic (1.52e-1)" "unprognostic (3.25e-2)" "unprognostic (2.46e-1)" "unprognostic (3.10e-3)" "unprognostic (1.09e-2)" 19.4 25.9 14.9 23.5 19.1 12.5 19.8 16.8 23.5 21.3 21.0 22.7 23.3 14.4 24.6 29.0 19.0 19.4 22.5 18.4 15.4 19.0 17.9 18.9 26.7 31.6 22.2 17.9 21.8 22.7 37.4 26.0 21.9 21.0 21.4 21.8 21.0 18.9 31.0 19.2 21.0 18.8 28.7 18.3 20.1 19.6 25.4 19.6 29.4 27.8 14.0 26.8 25.6 19.3 16.1 15.6 13.3 14.8 15.0 17.8 11.0 11.8 13.9 7.3 9.2 12.2 14.0 8.5 10.0 14.1 12.5 12.0 7.7 11.0 21.0 25.5 11.5 12.8 16.8 11.3 17.4 17.8 9.9 14.4 9.6 17.1 12.8 17.1 14.4 12.7 14.2 11.2 16.1 8.4 12.3 11.9 12.2 14.6 17.2 11.1 9.9 8.3 22.8 16.5 21.2 8.5 8.2 9.2 6.6 20.5 11.1 13.8 11.8 9.9 7.7 12.2 6.4 6.6 10.2 12.1 12.9 25.7 13.4 12.6 13.4 11.9 11.1 13.3 13.5 14.8 13.9 16.1 13.1 15.5 15.6 13.9 17.8 17.8 7.2 15.0 14.3 10.8 14.7 11.0 14.9 19.1 16.8 23.5 15.4 19.0 22.2 17.9 21.0 19.6 PCSK1 "NEC1, PC1, PC3, SPC3" ENSG00000175426 "Proprotein convertase subtilisin/kexin type 1" P29120 5 96390415-96434143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.6" "Group enriched" "Detected in some" 6 "SCLC-21H: 18.5;U-138 MG: 15.8;U-87 MG: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "basophil: 1.8" "Lineage enhanced" "Detected in single" "granulocytes: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048564 Approved "Secreted in other tissues" "HPA048564: " "unprognostic (1.86e-2)" "unprognostic (2.13e-2)" "unprognostic (4.66e-3)" "unprognostic (8.20e-5)" "prognostic unfavourable (9.13e-5)" "unprognostic (8.47e-4)" "unprognostic (1.46e-1)" "unprognostic (5.84e-3)" "unprognostic (4.71e-1)" "unprognostic (3.07e-3)" "unprognostic (1.89e-3)" "unprognostic (1.01e-1)" "unprognostic (7.90e-6)" "unprognostic (5.25e-2)" "unprognostic (9.96e-2)" "unprognostic (1.33e-3)" "unprognostic (9.37e-3)" 2.3 8.5 1.3 6.0 10.1 0.5 1.3 0.5 36.6 1.2 3.3 0.5 0.0 6.7 0.5 8.8 0.4 0.4 0.6 1.0 2.8 27.1 0.5 0.4 0.8 0.4 3.1 14.0 0.6 9.8 0.3 10.9 0.4 7.5 0.5 3.3 0.1 2.8 0.5 0.5 1.7 4.6 1.0 1.3 0.5 8.4 0.5 0.4 0.0 1.9 0.0 0.3 0.9 0.6 0.0 0.0 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.1 0.0 0.0 0.0 0.0 1.7 0.8 0.3 0.1 0.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 18.5 0.0 2.7 0.0 0.0 0.0 0.0 0.9 15.8 0.5 0.2 0.1 0.0 0.0 0.1 13.1 0.0 0.3 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 10.1 0.5 36.6 2.8 27.1 3.1 14.0 7.5 0.4 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 35.0;thyroid gland: 79.5" "Group enriched" "Detected in some" 5 "AF22: 35.8;SCLC-21H: 9.4" "Group enriched" "Detected in many" 6 "pancreatic cancer: 14.6;thyroid cancer: 65.1" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 22 "basophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" Vesicles "HPA049627: " "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 1.6 35.0 16.3 1.7 20.5 1.3 1.3 7.7 27.8 2.9 4.2 1.6 0.0 6.2 0.9 1.2 2.1 2.0 1.4 3.1 18.0 11.1 1.1 1.0 2.2 0.8 4.1 16.2 11.6 23.7 0.9 1.7 1.5 9.0 1.3 2.8 16.6 2.7 2.3 1.0 16.6 3.3 1.3 5.4 0.9 11.9 4.7 3.8 0.0 79.5 0.0 0.9 1.9 1.8 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 20.5 7.7 27.8 18.0 11.1 4.1 16.2 9.0 3.8 PDE10A ENSG00000112541 "Phosphodiesterase 10A" Q9Y233 6 165327287-165986603 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.8" "Cell line enhanced" "Detected in some" "LHCN-M2: 13.7;RH-30: 8.0;RT4: 8.4;SH-SY5Y: 8.4;TIME: 14.2;U-2 OS: 7.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 36.8" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 11 "basal ganglia: 307.0" "Group enriched" "Detected in all" 4 "basal ganglia: 155.2;cerebellum: 80.7" "CAB045998, HPA047200" Supported "CAB045998: AB_2162589, HPA047200: " "unprognostic (1.02e-1)" "unprognostic (3.63e-2)" "unprognostic (3.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (6.03e-2)" "unprognostic (3.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavourable (4.44e-7)" "unprognostic (3.59e-3)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (5.90e-3)" 3.1 1.9 1.7 1.0 36.8 0.0 3.4 4.5 6.9 2.2 1.0 1.1 4.3 0.8 2.9 7.5 0.7 3.1 3.2 3.6 2.6 2.1 8.8 0.9 4.3 1.4 2.7 1.1 3.4 0.8 1.2 2.5 5.3 1.7 2.6 0.5 0.6 0.7 4.9 0.9 0.6 0.8 4.3 1.1 2.5 1.2 8.7 16.0 0.0 12.2 1.0 0.8 7.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.7 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.3 0.0 7.6 0.0 0.5 0.0 0.0 0.1 0.0 0.6 0.0 7.4 0.0 0.0 13.7 0.1 1.1 0.0 1.5 5.5 1.7 8.0 0.0 7.2 8.4 2.2 8.4 0.0 0.0 0.4 0.0 0.0 14.2 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 36.8 4.5 6.9 2.6 2.1 2.7 1.1 1.7 16.0 PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623252-178072755 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 20.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.7;fHDF/TERT166: 5.5;HAP1: 3.1;Hep G2: 6.2" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA034560 Approved "Intracellular and membrane" "HPA034560: AB_10602140" "unprognostic (1.02e-1)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.61e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.91e-1)" "unprognostic (9.95e-2)" "unprognostic (2.80e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-4)" "unprognostic (1.64e-3)" 2.9 0.5 1.3 0.7 1.0 0.2 2.5 0.2 0.8 4.2 3.1 0.1 0.0 1.2 1.9 1.5 0.3 0.4 5.4 2.6 1.6 2.0 4.0 11.8 0.5 0.0 3.3 0.0 0.5 7.8 9.8 13.6 0.0 1.2 20.8 0.5 5.6 8.5 1.2 7.5 0.3 7.6 1.7 5.6 0.1 0.4 3.8 0.0 0.1 13.2 0.7 0.1 0.6 0.3 1.0 0.8 2.2 0.9 0.9 0.7 0.2 0.1 1.0 0.5 0.2 0.2 0.0 0.2 2.5 0.4 0.1 0.8 0.5 3.7 0.1 1.5 5.5 0.2 3.1 0.1 0.1 0.0 2.0 2.4 0.2 6.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.9 0.3 1.2 0.1 0.5 0.1 0.5 0.0 1.1 0.1 0.7 1.7 0.0 0.2 0.4 0.3 0.0 0.0 0.3 0.6 0.2 0.3 0.5 0.0 0.0 1.0 0.1 0.2 1.6 0.7 1.1 0.7 0.6 0.5 0.7 0.6 0.7 0.4 1.0 0.6 0.7 2.2 0.9 0.9 0.8 0.7 0.2 1.3 1.0 0.2 0.7 1.6 2.0 3.3 0.0 1.2 0.0 PDE12 "2'-PDE, 3635, DKFZp667B1218" ENSG00000174840 "Phosphodiesterase 12" Q6L8Q7 3 57556276-57566844 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043171 Approved "HPA043171: AB_10794654" "unprognostic (2.79e-1)" "unprognostic (3.18e-1)" "prognostic favourable (2.85e-5)" "unprognostic (2.39e-1)" "unprognostic (1.48e-1)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (8.43e-3)" "unprognostic (1.27e-1)" "unprognostic (6.45e-2)" "unprognostic (2.10e-1)" "unprognostic (9.88e-3)" "prognostic favourable (3.63e-8)" "unprognostic (6.97e-3)" "unprognostic (1.32e-1)" "unprognostic (7.85e-2)" "unprognostic (2.62e-1)" 14.2 22.1 10.0 13.7 15.7 21.1 11.2 18.0 18.4 10.7 12.4 16.9 10.6 15.7 14.9 8.5 19.8 10.9 12.7 11.2 11.0 10.8 16.8 22.1 11.4 14.3 15.5 10.6 15.7 17.0 18.2 15.5 12.7 13.6 11.8 12.2 13.2 14.6 12.4 19.1 11.4 13.8 12.2 12.4 12.6 13.8 9.9 14.2 21.7 13.0 11.7 16.4 14.1 11.6 10.4 10.1 16.6 12.6 14.5 13.4 9.5 12.9 12.8 8.0 14.9 10.4 7.4 14.6 11.0 10.6 12.4 11.1 16.9 8.8 21.3 4.4 9.9 8.6 17.0 11.5 10.3 9.7 8.9 16.0 11.2 12.8 11.8 20.7 16.6 10.1 7.9 15.0 13.3 10.7 13.2 15.7 11.2 10.0 18.4 6.8 12.4 22.1 7.0 6.5 15.7 10.0 15.1 7.1 11.5 11.9 14.0 11.8 10.6 12.0 13.1 10.4 9.9 19.7 17.7 15.4 22.3 18.7 12.2 16.3 15.3 16.6 9.1 8.2 11.6 12.6 12.9 7.2 10.9 11.9 10.1 10.4 13.4 13.4 2.6 14.5 12.5 5.4 12.9 9.5 10.0 15.7 18.0 18.4 11.0 10.8 15.5 10.6 13.6 14.2 PDE1A ENSG00000115252 "Phosphodiesterase 1A" P54750 2 182140036-182523192 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 66.0;kidney: 37.1" "Group enriched" "Detected in some" 5 "ASC diff: 22.3;HHSteC: 13.2;HSkMC: 28.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 1.4" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 6 "amygdala: 118.0;basal ganglia: 76.2;cerebral cortex: 161.5;hippocampal formation: 155.8;hypothalamus: 47.8" "Low region specificity" "Detected in many" HPA022151 Approved Approved Nucleoplasm Nucleoplasm "HPA022151: AB_1855118" "unprognostic (3.63e-1)" "unprognostic (7.21e-2)" "unprognostic (1.32e-1)" "unprognostic (8.61e-2)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (3.84e-1)" "unprognostic (3.82e-1)" "unprognostic (1.02e-1)" "unprognostic (5.38e-2)" "unprognostic (2.78e-1)" "unprognostic (2.86e-1)" "unprognostic (5.55e-3)" "unprognostic (2.50e-3)" "unprognostic (5.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.40e-3)" 7.6 3.9 13.8 3.6 11.5 0.5 4.1 66.0 25.3 11.5 8.8 6.2 1.7 2.6 7.3 6.7 4.7 7.4 18.2 11.8 12.6 4.1 37.1 3.2 3.1 1.8 7.1 15.7 9.2 2.0 1.3 2.3 1.3 6.9 3.8 5.6 3.0 1.8 4.8 2.4 2.1 4.6 11.8 10.1 2.6 4.6 24.6 9.0 0.0 35.1 2.6 1.1 8.3 9.0 0.0 1.4 0.8 0.2 0.0 0.0 0.0 0.0 0.1 2.2 0.0 22.3 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 0.0 3.1 0.0 13.2 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 4.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 3.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 13.8 11.5 66.0 25.3 12.6 4.1 7.1 15.7 6.9 9.0 PDE1B PDES1B ENSG00000123360 "Phosphodiesterase 1B" Q01064 12 54549350-54579239 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 52.6" "Cell line enhanced" "Detected in some" "HDLM-2: 11.3;HL-60: 6.3;HMC-1: 12.1;NB-4: 8.0;THP-1: 7.7;U-937: 6.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 52.6" "Cell type enriched" "Detected in single" 4 "naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 4 "T-cells: 1.6" "Region enriched" "Detected in all" 6 "basal ganglia: 895.2" "Region enriched" "Detected in all" 7 "basal ganglia: 253.8" HPA018492 Enhanced "HPA018492: AB_1855119" "unprognostic (2.90e-1)" "unprognostic (1.51e-1)" "unprognostic (7.67e-4)" "unprognostic (5.63e-3)" "unprognostic (7.02e-2)" "unprognostic (7.51e-2)" "unprognostic (1.97e-1)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "unprognostic (5.11e-2)" "unprognostic (3.84e-3)" "unprognostic (2.70e-2)" "prognostic unfavourable (4.77e-6)" "unprognostic (6.64e-4)" "unprognostic (2.14e-1)" "unprognostic (3.09e-1)" "unprognostic (2.83e-2)" 12.3 1.4 9.9 4.6 52.6 5.6 2.7 3.1 19.4 2.6 3.7 1.4 0.0 1.2 3.9 2.5 1.7 2.4 2.9 1.9 3.7 3.8 1.3 1.6 2.9 1.6 3.0 9.3 12.5 0.6 11.0 0.5 0.5 5.8 1.0 1.7 0.5 1.3 2.1 0.7 1.0 2.6 4.9 1.2 4.8 2.5 1.1 7.7 0.0 2.7 0.0 1.1 2.8 1.1 0.2 0.3 0.1 0.3 0.1 1.6 0.4 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.1 0.0 0.0 1.8 0.0 0.0 11.3 0.3 4.6 0.0 0.0 0.0 6.3 12.1 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.7 8.0 3.3 0.0 2.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.4 0.0 6.4 1.2 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.2 1.6 0.0 0.1 0.1 0.0 0.0 0.0 0.4 9.9 52.6 3.1 19.4 3.7 3.8 3.0 9.3 5.8 7.7 PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32299329 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease mutation, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.6;heart muscle: 56.2" "Cell line enhanced" "Detected in some" "BJ: 15.0;fHDF/TERT166: 48.3;U-251 MG: 26.1;WM-115: 34.5" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm Nucleoplasm "HPA052375: " "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" 2.9 2.7 10.6 3.2 27.7 0.9 5.1 2.4 17.1 1.2 2.7 30.1 0.0 2.3 3.1 6.8 7.4 8.4 2.4 56.2 14.8 7.5 4.0 1.0 5.0 1.4 31.1 12.0 4.9 2.7 1.3 1.3 4.0 16.3 2.9 2.7 7.9 2.6 4.2 1.4 0.9 2.8 10.4 17.1 1.4 3.8 4.2 33.6 0.0 3.9 0.2 1.0 7.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 5.2 0.0 0.2 0.1 0.0 15.0 6.1 7.1 5.8 0.0 0.0 0.0 0.0 48.3 0.4 0.0 0.0 9.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 10.8 0.6 0.0 1.4 0.0 2.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 7.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 2.9 0.1 26.1 0.0 0.0 0.0 0.7 0.1 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 27.7 2.4 17.1 14.8 7.5 31.1 12.0 16.3 33.6 PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.0;lymphoid tissue: 65.4" "Cell line enriched" "Detected in some" 8 "HeLa: 105.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 30.4;basal ganglia: 34.2;cerebral cortex: 48.0;hippocampal formation: 18.0;olfactory region: 27.0" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.7;T-cells: 9.6" "Group enriched" "Detected in many" 5 "amygdala: 111.5;basal ganglia: 166.3;cerebral cortex: 98.9;hippocampal formation: 120.9" "CAB009752, HPA031192" Enhanced Supported Cytosol Cytosol "CAB009752: AB_2268159, HPA031192: " "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favourable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" 27.8 18.4 30.4 3.0 34.2 2.5 25.4 1.0 48.0 8.9 7.7 3.8 1.9 3.5 9.4 4.9 10.2 11.6 12.0 11.3 18.0 6.1 7.0 10.4 5.1 3.8 3.8 27.0 3.4 2.4 4.4 3.4 6.6 6.7 4.8 5.2 3.0 2.3 6.3 6.6 4.8 4.2 10.3 2.1 65.4 4.2 2.9 7.4 0.1 7.0 3.9 2.2 8.3 11.2 3.7 1.2 0.2 1.0 0.1 9.6 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 2.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 105.0 0.1 0.2 0.0 1.6 0.0 0.2 0.5 4.3 2.3 0.1 0.1 0.0 0.0 0.0 0.0 1.5 2.9 0.0 0.0 0.2 0.0 0.0 9.4 0.5 0.0 0.0 0.4 0.0 0.0 13.4 0.0 2.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.8 0.0 9.6 1.0 5.6 3.7 5.7 5.6 1.2 2.5 3.7 3.0 0.2 0.1 0.5 0.0 2.3 1.9 30.4 34.2 1.0 48.0 18.0 6.1 3.8 27.0 6.7 7.4 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20369245-20684381 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.2" "Cell line enhanced" "Detected in some" "AF22: 7.7;HEL: 14.2;HeLa: 38.7;HUVEC TERT2: 6.9;SH-SY5Y: 14.5;U-138 MG: 11.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 35.4" "HPA014492, HPA074258" Uncertain Approved "Plasma membrane" 23000 "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavourable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 7.1 1.0 1.7 4.7 2.0 0.0 3.8 3.5 1.4 7.8 15.9 1.0 2.0 2.1 7.8 3.5 9.1 4.9 5.5 62.2 1.6 1.4 3.7 1.8 3.9 3.3 1.9 1.1 7.1 6.5 1.0 2.8 13.8 2.7 6.3 9.0 12.0 7.8 4.2 2.0 1.4 21.4 6.0 1.8 2.1 5.5 2.3 0.7 0.0 2.8 1.9 0.9 4.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 7.7 0.0 1.8 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.2 38.7 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.1 0.0 0.0 0.0 2.1 0.0 0.1 14.5 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.7 2.0 3.5 1.4 1.6 1.4 1.9 1.1 2.7 0.7 PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643723-14872044 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 42.6" "Cell line enhanced" "Detected in many" "HL-60: 13.3;Karpas-707: 15.4;THP-1: 16.3;U-266/70: 17.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 19.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 5.0;T-cells: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA056111: " "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.76e-3)" "unprognostic (4.25e-1)" "unprognostic (1.84e-3)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "prognostic favourable (7.91e-4)" "unprognostic (1.77e-1)" "unprognostic (2.33e-2)" "unprognostic (1.39e-2)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-3)" 42.6 1.0 2.3 12.6 2.2 6.7 17.0 19.2 3.0 2.9 21.8 0.9 0.8 2.2 0.9 1.4 2.6 1.0 6.9 4.7 2.2 2.1 2.4 18.2 10.2 14.1 1.6 1.6 0.9 7.3 0.3 5.1 5.5 1.5 10.7 8.1 1.9 16.5 1.3 0.8 0.9 6.3 9.7 2.1 8.7 3.0 12.5 0.8 7.8 1.2 2.3 7.1 10.5 4.5 0.3 0.4 5.0 1.2 0.1 8.7 1.8 0.0 1.5 3.3 5.4 6.6 0.0 1.3 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.1 11.1 0.1 8.1 10.0 2.3 13.3 0.0 0.5 0.0 0.0 0.3 0.0 11.7 15.4 0.0 0.1 2.6 6.5 4.5 2.4 6.4 1.5 10.0 0.0 1.1 5.1 9.5 1.3 8.6 2.9 0.0 16.3 0.0 0.0 0.8 0.0 0.0 17.4 5.3 0.4 0.1 2.3 1.0 0.0 0.7 2.9 1.4 0.7 2.9 0.3 4.2 3.2 0.4 0.2 8.7 7.5 5.0 0.1 1.2 0.1 4.2 1.8 2.3 2.2 19.2 3.0 2.2 2.1 1.6 1.6 1.5 0.8 PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469631 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5;testis: 31.8" "Cell line enhanced" "Detected in many" "HMC-1: 21.6;NB-4: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Plasma membrane" "Plasma membrane" "CAB017632: AB_1127109, HPA043310: , HPA076091: " "unprognostic (1.29e-2)" "unprognostic (3.98e-2)" "unprognostic (8.91e-2)" "unprognostic (1.82e-1)" "unprognostic (7.00e-2)" "unprognostic (6.84e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-2)" "unprognostic (6.90e-2)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (1.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.15e-1)" 6.4 2.5 9.0 4.2 13.9 3.4 6.3 15.0 38.5 8.4 4.3 3.2 0.4 2.0 4.4 1.1 3.1 4.8 5.0 4.1 12.4 6.9 2.8 1.9 7.7 2.0 5.3 19.4 1.7 9.8 17.3 2.3 4.9 34.7 3.7 3.0 3.1 7.1 4.0 26.1 2.2 2.7 4.7 3.6 4.1 6.1 31.8 4.5 0.0 5.4 1.0 1.9 4.6 3.5 0.2 3.3 5.9 4.4 5.3 2.0 1.3 0.0 1.4 0.3 3.9 11.4 6.8 2.2 3.2 6.5 0.4 1.1 3.4 3.1 1.4 9.6 8.4 0.3 2.2 0.4 0.2 3.7 3.2 13.4 4.7 3.7 7.4 2.2 21.6 5.0 0.4 3.6 0.0 3.1 10.5 3.2 2.3 0.9 1.3 24.9 1.7 2.8 8.8 2.2 11.5 0.5 0.8 2.5 0.9 0.2 0.1 3.5 0.5 4.4 6.5 4.9 6.3 3.3 2.0 6.4 0.5 7.1 2.1 0.1 3.9 5.9 2.6 5.1 1.5 4.4 0.8 0.2 0.5 2.0 3.3 0.1 0.1 0.7 0.2 5.3 4.4 0.2 1.2 1.3 9.0 13.9 15.0 38.5 12.4 6.9 5.3 19.4 34.7 4.5 PDE4B DPDE4 ENSG00000184588 "Phosphodiesterase 4B" Q07343 1 65792514-66374579 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.2" "Cell line enhanced" "Detected in many" "AN3-CA: 23.9;HUVEC TERT2: 35.9;NTERA-2: 21.8;SK-MEL-30: 21.6;TIME: 20.0;U-266/84: 18.8" "Cancer enhanced" "Detected in all" "glioma: 18.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 36.6" "Group enriched" "Detected in all" 5 "B-cells: 16.1;granulocytes: 36.6;T-cells: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003005 Uncertain Approved "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA003005: AB_1079587" "unprognostic (7.86e-2)" "unprognostic (3.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.90e-1)" "unprognostic (3.21e-1)" "unprognostic (3.33e-3)" "unprognostic (1.35e-1)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (6.10e-2)" "unprognostic (8.78e-2)" "unprognostic (4.24e-2)" "prognostic unfavourable (5.04e-4)" "unprognostic (2.89e-2)" "unprognostic (3.54e-1)" "unprognostic (9.04e-3)" "unprognostic (8.33e-3)" 14.9 2.9 21.5 28.4 29.0 48.2 15.0 12.7 31.9 6.4 6.6 39.2 0.7 3.9 6.7 2.1 3.9 3.5 8.1 16.1 20.7 18.8 3.7 8.7 10.0 15.9 36.3 14.2 2.0 1.7 1.7 3.4 13.1 32.2 18.3 8.6 6.6 15.9 10.3 28.2 6.2 8.5 9.5 37.4 18.5 4.2 3.2 36.9 2.3 5.5 5.5 14.7 16.1 3.9 16.1 2.6 36.6 2.8 4.4 13.3 3.7 0.0 6.8 13.5 23.9 0.7 0.7 0.0 4.4 5.2 4.2 5.5 0.0 0.0 2.0 0.1 8.2 0.0 0.1 0.0 4.1 5.8 0.0 0.1 1.9 0.0 0.5 4.8 0.0 1.4 0.2 2.1 0.1 35.9 0.0 1.3 1.8 0.1 0.0 2.8 21.8 0.3 0.9 2.4 1.3 3.3 0.0 0.1 10.4 0.0 1.1 21.6 0.1 1.7 20.0 3.3 0.8 1.8 0.7 0.6 18.8 7.3 3.4 5.0 1.4 2.7 2.8 8.4 4.4 2.4 8.4 15.4 8.3 6.2 2.4 16.1 9.4 6.5 36.6 4.4 2.1 2.6 13.3 3.7 21.5 29.0 12.7 24.6 20.7 18.8 36.3 14.2 32.2 36.9 PDE4C DPDE1 ENSG00000105650 "Phosphodiesterase 4C" Q08493 19 18208652-18248200 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 28.6" "Cell line enhanced" "Detected in some" "BEWO: 5.9;Hep G2: 3.9;U-87 MG: 8.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" HPA048975 Approved "HPA048975: " "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (5.22e-4)" "unprognostic (1.44e-2)" "unprognostic (7.70e-2)" "unprognostic (1.15e-1)" "unprognostic (4.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-3)" "unprognostic (2.21e-1)" "unprognostic (7.25e-10)" "unprognostic (2.73e-2)" "unprognostic (2.65e-1)" "unprognostic (9.21e-2)" "unprognostic (2.45e-2)" 2.0 1.3 1.8 1.5 2.8 1.0 2.0 0.8 6.1 4.1 4.4 1.5 3.1 1.5 6.4 6.8 1.3 4.2 5.6 4.2 1.6 1.9 4.1 2.0 4.1 0.5 1.7 5.1 2.0 0.8 0.3 3.5 7.0 2.8 5.8 1.3 2.5 1.3 5.4 13.4 0.6 4.1 3.4 0.7 2.3 5.2 2.6 1.1 0.4 1.2 28.6 0.7 1.8 3.3 1.3 0.6 3.5 0.7 1.0 0.7 0.2 0.1 0.3 0.2 0.3 0.1 0.3 5.9 0.1 0.0 0.2 0.3 1.2 0.2 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.4 3.9 0.2 0.2 0.5 0.7 0.1 2.5 0.0 0.0 0.9 2.0 0.1 0.4 0.2 0.3 0.1 0.2 0.2 0.3 0.4 0.1 0.2 0.2 0.8 0.3 0.5 0.0 0.5 0.3 0.0 0.4 0.2 0.7 0.1 1.3 0.6 0.2 8.8 0.2 0.3 3.4 0.7 1.0 0.6 0.4 0.5 0.5 0.5 0.4 0.2 1.3 0.5 0.7 3.5 1.0 0.4 0.6 0.3 0.2 1.8 2.8 0.8 6.1 1.6 1.9 1.7 5.1 2.8 1.1 PDE4D DPDE3 ENSG00000113448 "Phosphodiesterase 4D" Q08499 5 58969038-60522120 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.0" "Cell line enhanced" "Detected in many" "A549: 24.8;AN3-CA: 28.5;HeLa: 41.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "eosinophil: 28.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045895 Approved Supported "Plasma membrane,Cytosol" "Plasma membrane" Cytosol "HPA045895: AB_10960275" "unprognostic (1.14e-1)" "unprognostic (8.73e-3)" "unprognostic (4.35e-2)" "unprognostic (7.87e-2)" "unprognostic (5.97e-2)" "unprognostic (2.03e-1)" "unprognostic (8.10e-4)" "unprognostic (1.17e-1)" "unprognostic (6.59e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "prognostic favourable (4.00e-5)" "unprognostic (1.51e-1)" "unprognostic (8.20e-2)" "unprognostic (1.77e-2)" "unprognostic (2.56e-2)" 8.2 1.9 4.4 6.8 8.6 46.2 5.3 4.2 13.0 13.5 18.6 1.4 14.7 4.1 17.1 14.0 10.3 6.6 12.7 15.5 4.5 5.8 12.8 3.4 11.1 3.7 5.2 6.6 5.3 2.9 7.0 9.0 11.8 2.7 18.2 11.2 8.6 24.4 16.5 60.0 5.1 7.5 35.8 5.0 3.8 10.2 2.6 2.8 4.4 6.2 11.3 9.5 20.0 11.2 6.1 0.7 28.1 1.1 0.1 0.8 0.5 0.0 24.8 5.2 28.5 0.9 1.8 4.1 0.6 0.7 1.4 2.0 9.7 0.8 1.9 0.1 0.2 4.2 0.0 1.1 2.4 1.1 2.8 3.6 41.0 2.1 3.8 1.7 0.2 3.8 0.9 3.9 0.7 2.9 0.0 0.6 2.4 1.7 1.3 4.0 0.9 1.3 0.4 6.5 4.1 6.5 9.3 0.9 3.3 6.5 11.0 5.6 0.8 3.7 3.4 0.3 0.1 4.9 1.3 1.4 0.0 0.2 4.2 6.8 1.1 2.0 1.1 28.1 0.8 0.0 0.8 6.1 0.7 0.3 0.7 6.1 0.5 0.4 1.5 0.1 0.1 0.0 0.4 0.5 4.4 8.6 4.2 13.0 4.5 5.8 5.2 6.6 2.7 2.8 PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494395-119628991 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.3;HHSteC: 35.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved "Centriolar satellite,Cytosol" 3100000 Cytosol "Centriolar satellite" "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favourable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavourable (1.17e-4)" 12.3 4.9 2.0 28.2 2.3 0.4 8.1 3.0 2.3 21.3 28.0 1.7 20.1 6.5 17.3 21.4 30.7 10.7 13.3 5.3 2.0 2.8 3.8 1.2 11.4 4.1 2.4 3.4 10.0 7.8 5.1 3.4 8.9 4.4 31.8 11.7 20.2 8.5 23.7 6.8 4.2 15.6 45.6 2.0 2.1 9.1 7.6 1.2 0.9 9.1 8.1 2.2 25.9 15.9 1.5 0.5 1.4 0.4 0.6 2.1 4.2 8.0 0.4 5.7 0.6 1.9 2.9 1.0 5.4 24.3 0.2 0.5 0.5 0.7 0.8 0.2 6.7 2.9 1.8 0.8 0.7 0.2 3.7 9.0 1.4 0.4 35.0 1.9 0.9 3.2 1.7 0.6 0.0 0.7 1.0 1.5 0.8 0.4 2.4 0.3 1.2 1.4 0.3 2.9 2.1 2.1 2.4 2.2 4.5 6.3 7.9 0.6 1.4 1.0 1.2 3.2 2.8 1.7 0.7 2.1 1.0 0.7 3.1 0.5 0.4 0.0 0.3 0.0 0.6 0.1 2.1 1.5 1.3 0.4 0.2 1.0 0.6 0.9 1.4 0.6 0.4 0.5 0.4 4.2 2.0 2.3 3.0 2.3 2.0 2.8 2.4 3.4 4.4 1.2 PDE6A "PDEA, RP43" ENSG00000132915 "Phosphodiesterase 6A" P16499 5 149857955-149944793 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 153.4" "Cell line enriched" "Detected in some" 4 "CACO-2: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016970, HPA074677" Enhanced "HPA016970: AB_1855125, HPA074677: AB_2732264" "unprognostic (6.85e-2)" "unprognostic (8.84e-2)" "unprognostic (1.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (4.39e-3)" "unprognostic (8.83e-2)" "unprognostic (6.54e-2)" "unprognostic (5.91e-3)" "unprognostic (1.77e-2)" "unprognostic (9.21e-2)" "unprognostic (7.57e-5)" "unprognostic (9.93e-2)" "unprognostic (3.08e-1)" "unprognostic (1.31e-1)" "unprognostic (2.26e-2)" 0.2 2.3 0.2 0.2 0.2 0.9 0.2 0.3 0.2 0.2 1.8 0.2 0.3 0.2 0.2 20.1 2.4 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 4.6 0.2 0.2 0.2 1.0 153.4 1.4 0.2 0.2 1.6 0.2 0.2 0.2 0.2 0.1 3.1 0.2 0.2 0.4 0.3 0.5 0.2 0.2 1.5 0.8 3.3 0.8 1.2 0.8 0.1 0.4 0.7 0.6 0.5 0.3 0.3 0.6 0.3 0.1 0.4 0.1 7.4 0.8 0.9 1.3 0.2 0.7 0.2 0.4 0.5 0.6 0.3 1.0 1.1 0.6 0.2 0.7 0.6 0.3 1.1 0.9 0.6 0.2 0.3 1.4 1.4 0.3 0.4 0.9 0.5 0.5 0.3 0.8 0.7 0.5 0.9 0.8 1.1 0.0 0.7 0.2 1.0 0.5 1.4 0.8 1.6 0.8 0.5 0.6 0.3 0.5 0.8 0.8 0.6 3.3 0.8 0.5 0.6 0.4 0.5 0.7 0.6 0.5 0.2 1.5 0.7 0.8 2.8 1.2 0.5 0.8 0.4 0.1 0.2 0.2 0.3 0.2 0.2 0.0 0.2 0.2 0.2 0.2 PDE6B "CSNB3, CSNBAD2, PDEB, rd1, RP40" ENSG00000133256 "Phosphodiesterase 6B" P35913 4 625584-670782 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Congenital stationary night blindness, Disease mutation, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2;retina: 64.2" "Cell line enhanced" "Detected in some" "EFO-21: 8.0;MOLT-4: 20.5;REH: 11.1;SCLC-21H: 14.0;SH-SY5Y: 8.2;U-266/84: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054148, HPA059929" Enhanced Approved Cytosol Cytosol "HPA054148: , HPA059929: " "unprognostic (2.43e-2)" "unprognostic (1.33e-4)" "unprognostic (2.45e-4)" "unprognostic (7.18e-3)" "unprognostic (1.88e-2)" "unprognostic (5.04e-3)" "unprognostic (7.32e-3)" "prognostic favourable (5.34e-4)" "unprognostic (9.70e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.67e-2)" "unprognostic (2.26e-1)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" 1.6 1.9 12.1 4.6 19.1 6.7 3.8 2.3 13.2 2.3 1.3 30.2 1.5 0.8 2.5 3.9 1.4 9.6 3.2 5.2 18.1 10.2 4.6 0.7 4.2 12.0 29.6 9.8 2.6 1.4 9.1 3.2 2.6 14.5 2.5 1.0 64.2 3.5 2.9 0.7 1.8 2.2 2.1 20.2 8.7 2.5 3.6 22.4 4.3 11.4 0.2 8.3 4.1 1.1 16.5 14.1 11.2 5.8 10.2 13.1 7.1 0.0 0.2 0.8 0.4 0.2 0.3 0.2 0.0 0.0 0.5 1.4 0.0 0.1 0.2 8.0 0.2 0.1 1.7 0.4 0.0 0.1 0.0 0.6 0.2 0.0 4.1 0.1 0.3 0.5 0.1 2.4 0.0 0.7 0.1 0.6 0.0 0.2 20.5 0.2 6.5 0.2 11.1 0.2 0.4 1.4 0.9 14.0 8.2 0.0 0.3 0.1 0.4 0.0 0.2 0.1 0.8 0.1 0.3 5.4 15.2 0.2 0.2 0.2 0.1 11.2 4.2 0.6 11.5 5.8 10.5 10.0 7.7 7.9 6.6 16.5 12.2 13.1 1.1 10.2 5.6 14.1 11.4 7.1 12.1 19.1 2.3 10.0 18.1 10.2 29.6 9.8 14.5 22.4 PDE6C "ACHM5, COD4, PDEA2" ENSG00000095464 "Phosphodiesterase 6C" P51160 10 93612588-93666010 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 12.8" "Cell line enhanced" "Detected in some" "Hep G2: 2.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (1.39e-3)" "unprognostic (7.41e-3)" "unprognostic (2.61e-2)" "unprognostic (2.24e-1)" "unprognostic (3.17e-2)" "unprognostic (5.23e-3)" "unprognostic (2.46e-3)" "unprognostic (2.81e-3)" "unprognostic (9.68e-2)" "unprognostic (2.64e-1)" "unprognostic (1.51e-2)" "unprognostic (2.96e-3)" "unprognostic (2.19e-7)" "unprognostic (1.19e-1)" "unprognostic (6.61e-2)" "unprognostic (1.81e-1)" "unprognostic (1.80e-3)" 0.4 0.6 0.3 0.4 0.4 1.3 0.4 3.0 0.7 0.8 0.3 0.3 0.3 0.4 0.5 0.3 0.3 0.5 0.3 0.3 0.3 0.2 0.3 0.5 0.5 1.0 0.3 0.3 1.0 0.3 0.0 0.8 0.3 0.3 0.7 0.0 12.8 0.8 0.3 3.1 3.1 0.7 0.3 0.3 0.9 0.6 0.7 0.3 0.3 0.6 0.3 0.3 0.4 0.7 0.2 0.1 0.2 0.2 0.3 0.6 0.0 0.2 0.7 0.4 1.4 0.0 0.1 1.0 0.8 0.0 0.0 0.0 0.7 1.0 0.6 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.5 1.4 2.4 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 1.0 1.5 0.8 0.4 0.6 0.0 0.1 0.0 0.2 1.2 0.1 0.2 0.0 0.1 0.5 0.3 0.2 0.0 0.4 0.0 0.2 0.7 0.6 0.6 0.5 0.4 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.6 0.5 0.2 0.3 0.2 0.1 0.0 0.0 0.3 0.4 3.0 0.3 0.3 0.2 0.3 0.3 0.3 0.3 PDE6G "PDEG, RP57" ENSG00000185527 "Phosphodiesterase 6G" P18545 17 81650459-81663112 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 260.3" "Cell line enhanced" "Detected in some" "Hep G2: 6.4;NB-4: 6.8;NTERA-2: 11.8;REH: 13.7" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 29.7;NK-cell: 57.8" "Group enriched" "Detected in all" 5 "granulocytes: 29.7;NK-cells: 57.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles Vesicles "HPA045118: " "unprognostic (6.16e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.51e-3)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "unprognostic (6.33e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (4.85e-2)" "unprognostic (5.01e-2)" "unprognostic (1.94e-2)" "unprognostic (5.71e-2)" "unprognostic (5.44e-2)" "unprognostic (2.73e-1)" "unprognostic (1.14e-1)" 0.9 1.3 0.4 2.9 0.5 4.7 0.7 0.5 0.6 0.4 0.8 0.5 0.4 0.0 0.4 0.5 0.6 0.3 1.6 0.5 0.5 0.7 3.8 2.6 2.0 13.8 0.6 0.5 0.5 0.4 0.0 0.5 8.6 0.5 0.5 0.5 260.3 0.5 0.4 0.6 0.8 2.8 0.4 0.8 17.9 0.7 2.2 0.5 2.5 0.6 0.4 4.6 2.1 0.4 1.3 8.6 29.7 7.7 57.8 2.4 3.7 0.2 0.3 0.5 0.0 0.3 0.0 0.0 0.3 1.2 1.2 1.3 0.1 0.8 0.6 0.2 0.7 0.1 0.2 0.2 2.9 0.2 0.0 0.9 0.1 6.4 1.0 0.1 0.2 0.0 0.2 1.2 0.0 3.3 0.1 0.3 1.3 0.8 0.1 6.8 11.8 0.4 13.7 0.1 2.1 0.0 0.0 0.1 0.3 0.0 0.3 0.5 0.1 0.8 1.3 0.4 0.1 0.2 0.3 0.1 0.6 1.0 1.6 2.7 0.2 29.7 5.1 8.6 1.2 7.7 0.4 0.8 0.3 0.6 8.6 1.3 0.7 2.4 0.7 57.8 4.2 0.8 0.0 3.7 0.4 0.5 0.5 0.6 0.5 0.7 0.6 0.5 0.5 0.5 PDE6H ENSG00000139053 "Phosphodiesterase 6H" Q13956 12 14973022-14981865 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "retina: 67.4" "Group enriched" "Detected in some" 4 "AN3-CA: 4.2;MOLT-4: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles Vesicles "HPA045118: " "unprognostic (1.47e-3)" "unprognostic (1.07e-2)" 0.1 1.3 1.2 0.2 1.5 9.4 0.1 0.1 4.2 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 1.0 2.1 0.1 0.1 0.2 0.2 2.2 0.1 0.1 0.1 0.0 0.1 2.5 0.7 0.1 0.1 67.4 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.8 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.6 0.7 0.0 0.0 1.4 0.2 0.0 0.8 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 1.2 1.5 0.1 4.2 1.0 2.1 2.2 0.1 0.7 0.1 PDE7A HCP1 ENSG00000205268 "Phosphodiesterase 7A" Q13946 8 65717510-65842322 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 87.5;skeletal muscle: 48.3" "Cell line enhanced" "Detected in many" "Karpas-707: 32.1;MOLT-4: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018770, HPA027340" Approved "CAB018770: AB_677329, HPA027340: AB_1855127" "unprognostic (2.76e-1)" "unprognostic (2.94e-2)" "unprognostic (1.36e-1)" "unprognostic (1.17e-2)" "unprognostic (2.15e-1)" "unprognostic (7.11e-2)" "prognostic unfavourable (5.64e-4)" "unprognostic (1.44e-2)" "unprognostic (6.94e-2)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.56e-1)" "prognostic unfavourable (1.35e-4)" "unprognostic (3.08e-2)" "unprognostic (1.26e-1)" "unprognostic (5.06e-2)" "unprognostic (2.03e-2)" 6.9 1.4 4.4 22.7 4.6 12.3 10.0 7.3 4.3 7.1 4.1 5.8 5.9 5.6 3.6 8.2 3.6 3.8 6.1 21.0 4.3 3.6 13.4 2.7 10.1 27.7 4.3 2.7 3.4 9.2 1.4 7.5 4.0 4.6 7.3 5.0 3.3 11.7 12.6 48.3 4.3 13.6 4.0 3.4 16.3 6.2 4.8 5.5 87.5 13.0 25.4 22.4 5.4 4.7 7.7 2.2 5.3 0.7 2.1 12.6 1.8 4.0 3.6 15.9 7.4 2.3 2.0 6.7 3.0 2.6 3.9 3.7 4.4 2.7 11.4 0.7 1.9 4.5 5.8 6.4 4.1 13.4 3.0 8.3 5.7 3.1 1.1 6.6 3.3 2.9 10.8 2.5 7.6 3.8 6.1 32.1 2.6 2.3 53.5 8.2 16.9 1.6 20.0 2.4 2.9 2.6 8.1 7.9 9.0 3.2 1.6 1.6 8.7 17.1 2.4 5.4 6.7 3.8 2.4 15.7 6.7 19.8 5.5 13.9 2.9 0.2 0.7 5.3 3.7 0.6 6.0 6.7 5.7 3.7 1.5 7.7 12.6 9.6 2.6 2.1 0.1 2.2 4.5 1.8 4.4 4.6 7.3 4.3 4.3 3.6 4.3 2.7 4.6 5.5 PDE7B ENSG00000171408 "Phosphodiesterase 7B" Q9NP56 6 135851696-136195574 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 7.1;ASC TERT1: 8.5;EFO-21: 13.1;HeLa: 7.6;HSkMC: 18.3;HUVEC TERT2: 8.5;U-2197: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 4.3" "Low lineage specificity" "Detected in many" "Region enriched" "Detected in all" 5 "basal ganglia: 112.3" "Low region specificity" "Detected in all" HPA023967 Uncertain Approved Nucleoplasm Nucleoplasm "HPA023967: AB_1855128" "unprognostic (3.18e-1)" "unprognostic (3.47e-1)" "unprognostic (2.34e-1)" "unprognostic (1.79e-3)" "unprognostic (3.34e-1)" "unprognostic (3.22e-4)" "unprognostic (1.37e-2)" "unprognostic (3.00e-1)" "unprognostic (2.80e-1)" "unprognostic (6.73e-3)" "unprognostic (1.11e-2)" "unprognostic (7.85e-2)" "prognostic favourable (1.59e-4)" "unprognostic (3.14e-3)" "unprognostic (2.68e-2)" "unprognostic (1.43e-1)" "unprognostic (3.34e-2)" 5.8 4.3 7.3 4.0 21.9 0.8 3.6 1.6 12.8 6.2 4.0 2.3 25.2 3.6 14.2 4.9 2.8 4.2 6.1 7.9 5.1 7.4 9.6 6.4 3.3 2.8 6.4 4.2 22.7 1.6 3.7 8.7 2.2 5.9 6.8 5.0 5.4 5.0 28.5 7.2 1.5 3.7 13.5 5.3 2.3 5.2 2.9 7.1 7.7 8.3 6.1 1.9 10.6 5.1 4.3 2.6 0.6 0.9 0.7 1.8 0.3 0.0 4.4 0.1 0.0 7.1 8.5 0.0 0.4 2.3 1.7 0.9 0.0 0.0 0.0 13.1 2.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 7.6 0.0 3.1 0.1 0.0 18.3 0.0 3.4 0.0 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.0 0.5 3.1 2.9 0.1 0.1 0.0 1.5 0.0 1.8 0.0 9.1 0.0 0.1 0.0 0.0 0.5 0.0 0.7 0.2 0.9 0.6 0.2 0.2 0.1 1.5 0.4 0.2 2.6 4.3 1.8 1.0 0.3 0.7 0.1 0.2 0.2 0.3 7.3 21.9 1.6 12.8 5.1 7.4 6.4 4.2 5.9 7.1 PDE8A HsT19550 ENSG00000073417 "Phosphodiesterase 8A" O60658 15 84980440-85139145 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007722 Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA007722: AB_1855130" "unprognostic (1.68e-1)" "unprognostic (2.83e-2)" "unprognostic (4.81e-2)" "unprognostic (4.97e-2)" "unprognostic (6.25e-2)" "unprognostic (3.47e-2)" "unprognostic (2.97e-2)" "unprognostic (3.94e-2)" "unprognostic (1.03e-1)" "unprognostic (2.45e-1)" "unprognostic (8.99e-3)" "unprognostic (2.75e-2)" "unprognostic (3.42e-1)" "unprognostic (3.72e-1)" "unprognostic (4.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.94e-2)" 14.3 16.6 14.0 8.5 18.7 2.6 9.8 2.6 14.8 11.4 21.0 35.5 9.1 13.2 9.0 8.2 5.9 8.8 14.3 7.8 17.2 9.8 21.7 26.2 10.5 5.4 23.3 12.1 12.0 12.7 17.6 7.1 10.1 20.1 6.9 19.8 12.6 8.2 9.2 5.6 6.2 11.7 10.7 17.6 6.7 10.8 10.6 25.5 2.2 11.2 4.8 5.0 11.9 10.6 1.3 1.7 1.7 4.5 0.6 3.2 0.6 12.6 21.1 3.6 2.4 15.2 8.1 4.3 8.4 9.5 7.6 8.8 4.7 7.5 2.5 6.7 11.4 9.0 15.3 6.7 10.2 4.6 9.1 3.4 13.7 6.8 11.0 1.9 5.1 8.1 4.1 8.9 8.5 9.7 6.7 8.3 6.8 10.6 1.1 1.9 1.7 3.9 1.5 2.9 3.5 6.0 39.5 8.4 6.4 8.4 9.2 24.6 3.0 3.8 7.6 17.8 6.2 6.3 13.8 4.0 7.1 2.7 12.1 7.9 5.0 0.0 2.4 1.7 1.1 2.2 2.1 0.8 1.8 1.9 1.7 1.3 2.2 0.9 0.2 0.6 4.5 0.0 3.2 0.6 14.0 18.7 2.6 14.8 17.2 9.8 23.3 12.1 20.1 25.5 PDE8B ENSG00000113231 "Phosphodiesterase 8B" O95263 5 77210449-77429807 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "Cushing syndrome, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "thyroid gland: 67.7" "Group enriched" "Detected in some" 4 "BJ hTERT+: 12.1;HeLa: 27.8;SK-BR-3: 7.4" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 35.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "HPA036911, HPA036912" Supported Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA036911: , HPA036912: AB_10670377" "unprognostic (1.30e-1)" "unprognostic (7.95e-2)" "unprognostic (3.35e-2)" "unprognostic (7.61e-4)" "unprognostic (1.59e-2)" "unprognostic (1.41e-1)" "unprognostic (2.66e-2)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.26e-2)" "unprognostic (3.98e-2)" "unprognostic (2.44e-1)" "unprognostic (9.04e-3)" "unprognostic (3.40e-2)" "unprognostic (3.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.19e-2)" 6.8 2.5 9.9 0.7 14.2 0.4 3.8 1.1 16.3 6.3 1.2 2.3 0.3 1.2 11.3 3.2 1.1 10.1 2.1 7.9 8.2 9.2 3.1 1.2 2.2 0.7 5.4 8.3 1.9 4.2 0.3 3.8 13.1 8.6 10.5 0.8 2.0 5.3 7.1 0.4 0.7 1.3 10.3 2.3 0.4 1.5 1.5 5.7 0.3 67.7 0.3 0.7 0.8 1.4 0.2 0.8 1.4 2.3 0.4 0.4 0.1 0.3 3.3 1.3 0.3 1.2 0.0 0.5 1.1 12.1 0.2 0.1 1.3 0.2 0.5 0.2 0.1 0.9 0.1 0.0 0.2 0.2 1.0 0.7 27.8 0.3 0.0 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.6 0.7 0.8 0.1 0.8 1.4 0.7 0.0 0.3 3.7 1.0 1.6 7.4 0.8 1.6 1.1 0.6 0.4 0.2 0.2 0.6 0.9 0.5 0.6 1.6 0.7 0.4 0.0 0.3 1.4 0.3 2.2 0.1 0.2 0.2 0.3 0.8 0.2 0.4 0.0 0.3 0.4 2.3 0.5 0.1 0.1 9.9 14.2 1.1 16.3 8.2 9.2 5.4 8.3 8.6 5.7 PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653636-42775509 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 16.1;EFO-21: 16.2;MCF7: 12.0;NB-4: 17.9;NTERA-2: 22.1;SCLC-21H: 12.3" "Cancer enhanced" "Detected in all" "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 6.8" "Group enriched" "Detected in many" 4 "NK-cells: 1.7;T-cells: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011380 Enhanced Approved Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA011380: AB_1855132" "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" 6.1 6.6 9.9 6.8 15.2 0.8 9.4 13.7 9.0 3.7 37.1 11.9 14.0 3.0 5.7 18.8 6.1 10.3 7.7 3.5 6.2 7.7 13.2 2.5 4.7 4.6 10.0 4.9 4.1 4.0 4.7 6.0 9.6 6.9 33.2 15.8 9.7 8.8 15.9 2.3 3.8 26.1 22.3 8.0 15.9 8.4 1.5 8.9 4.9 5.2 2.1 4.1 12.6 4.0 0.5 0.9 1.0 0.1 1.7 6.8 0.5 0.0 1.5 16.1 1.9 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.7 9.7 0.0 16.2 0.0 0.0 1.4 5.2 0.0 0.0 5.5 0.0 0.0 3.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 12.0 0.8 17.9 22.1 0.0 0.0 0.0 0.6 11.0 4.4 12.3 7.3 2.7 0.0 0.2 0.1 9.9 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.1 0.6 0.2 0.5 6.8 1.7 1.0 1.7 0.1 0.9 2.2 0.5 9.9 15.2 13.7 6.7 6.2 7.7 10.0 4.9 6.9 8.9 PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69328621-69330595 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Mitochondria Nucleoplasm "HPA063409: " "unprognostic (4.28e-2)" "prognostic unfavourable (4.63e-4)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-1)" "prognostic unfavourable (2.73e-4)" "unprognostic (2.98e-3)" "prognostic unfavourable (7.35e-4)" "unprognostic (5.84e-2)" "unprognostic (4.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.00e-1)" "prognostic favourable (6.11e-4)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-2)" 6.6 7.9 4.8 7.8 4.5 5.3 4.8 3.1 6.9 3.6 7.6 3.8 3.3 7.1 5.3 5.6 8.4 4.4 6.5 3.8 4.6 3.3 14.9 30.2 3.7 7.0 3.0 5.2 5.0 14.2 8.2 3.9 4.9 4.4 5.3 4.1 4.3 12.8 4.6 10.4 6.0 5.2 3.4 2.3 5.0 8.3 3.7 2.0 10.2 7.3 9.2 6.2 3.7 4.0 10.3 3.2 2.5 2.8 1.7 6.9 1.5 8.9 6.0 1.2 2.9 1.8 1.3 10.6 7.5 2.0 5.4 4.7 14.9 6.4 16.6 10.0 2.6 12.9 3.7 4.0 2.2 4.0 30.8 8.4 5.7 21.3 3.7 11.7 6.7 2.8 7.1 4.8 2.3 3.1 20.2 1.9 2.9 11.5 9.1 12.3 7.7 11.1 21.6 1.9 15.4 4.3 5.6 10.3 8.2 13.0 2.2 6.3 12.8 3.8 4.6 4.6 8.8 5.4 8.7 15.7 10.4 19.6 3.1 8.7 6.0 0.0 2.8 2.5 1.2 1.6 3.1 4.3 3.9 3.9 3.0 10.3 6.9 2.5 0.0 1.7 1.5 3.2 3.0 1.5 4.8 4.5 3.1 6.9 4.6 3.3 3.0 5.2 4.4 2.0 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926066 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 33.2;TIME: 33.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 38.9;cerebral cortex: 62.2;olfactory region: 32.5" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol Nucleoplasm "Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavourable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavourable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favourable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 5.1 32.3 11.0 4.6 38.9 5.9 7.9 7.5 62.2 7.5 4.3 4.7 1.6 3.3 7.7 8.6 8.0 6.1 9.6 22.9 10.1 8.0 6.3 2.2 6.0 5.6 5.1 32.5 9.7 9.3 20.6 4.2 6.6 4.4 5.2 6.2 4.4 6.6 4.7 31.8 3.2 5.5 5.5 3.4 5.8 5.5 12.9 4.8 4.1 9.3 7.0 5.8 7.7 5.1 11.0 12.7 7.8 21.5 2.8 19.5 8.8 8.9 4.4 9.6 4.0 8.0 14.6 3.2 7.0 7.8 8.3 9.8 4.6 33.2 5.0 23.7 11.2 19.9 4.1 5.9 12.3 0.5 2.0 2.3 5.5 1.6 9.1 1.1 3.3 9.4 11.8 14.1 22.6 18.7 0.8 8.2 10.1 2.1 6.9 3.6 4.4 5.7 1.7 5.7 0.9 5.7 6.2 0.8 4.2 4.6 0.5 21.6 1.5 1.4 33.2 10.1 6.5 23.6 8.3 4.6 1.9 4.2 12.9 4.2 8.9 3.1 15.4 7.8 5.6 14.3 5.3 9.3 9.1 7.2 12.7 11.0 5.5 4.8 1.8 2.8 21.5 2.1 19.5 8.8 11.0 38.9 7.5 62.2 10.1 8.0 5.1 32.5 4.4 4.8 PDP2 "KIAA1348, PPM2B, PPM2C2" ENSG00000172840 "Pyruvate dehyrogenase phosphatase catalytic subunit 2" Q9P2J9 16 66878589-66895754 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019950, HPA062059" Approved Supported Mitochondria Mitochondria "HPA019950: AB_1855156, HPA062059: " "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (5.44e-2)" "unprognostic (1.17e-1)" "unprognostic (4.90e-3)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "prognostic favourable (9.75e-7)" "unprognostic (1.89e-1)" "unprognostic (5.10e-1)" "unprognostic (3.20e-1)" "unprognostic (6.15e-2)" 10.7 7.2 7.4 3.7 10.5 3.2 8.7 11.5 16.5 4.9 7.5 10.1 5.7 10.4 7.9 7.2 8.9 7.2 6.0 4.8 7.4 7.1 18.1 16.5 8.6 5.0 9.0 9.4 14.9 13.8 12.0 7.0 7.7 16.0 7.8 8.4 8.5 7.1 6.9 6.3 4.7 6.2 4.6 6.3 4.0 6.7 8.6 8.9 4.6 18.0 4.0 5.9 6.3 5.5 3.3 1.3 1.8 0.4 6.1 6.3 2.0 7.2 8.8 5.5 10.7 14.7 7.6 6.9 3.7 14.7 8.8 13.2 17.9 5.1 10.0 5.4 5.3 9.1 15.8 8.5 8.5 2.3 8.0 5.0 4.4 11.6 8.0 6.4 8.9 5.7 6.4 12.4 12.9 3.7 9.6 7.2 7.8 4.7 12.5 4.6 6.4 11.2 12.3 7.6 15.8 4.6 7.7 11.0 6.2 12.1 5.0 4.5 6.6 3.1 3.5 5.4 7.3 3.2 5.5 12.8 11.8 10.0 7.4 5.1 5.3 1.3 0.4 1.8 6.3 0.3 5.2 1.8 3.1 5.1 1.3 3.3 4.5 5.0 1.3 6.1 0.2 0.8 0.9 2.0 7.4 10.5 11.5 16.5 7.4 7.1 9.0 9.4 16.0 8.9 PDXP "CIN, dJ37E16.5, FLJ32703" ENSG00000241360 "Pyridoxal phosphatase" Q96GD0 22 37658727-37666934 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.4;liver: 34.7" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 8 "plasmacytoid DC: 12.9" "Lineage enriched" "Detected in many" 8 "dendritic cells: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000531 Approved 17000 "HPA000531: " "unprognostic (6.29e-2)" "unprognostic (7.89e-3)" "unprognostic (1.00e-1)" "unprognostic (2.89e-1)" "unprognostic (2.15e-2)" "unprognostic (3.25e-2)" "unprognostic (2.81e-1)" "unprognostic (4.44e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (1.57e-3)" "unprognostic (2.76e-2)" "unprognostic (1.77e-1)" "unprognostic (3.03e-3)" "unprognostic (2.04e-1)" "unprognostic (4.66e-2)" "unprognostic (2.38e-1)" 2.4 14.8 43.5 1.7 32.0 3.0 2.5 24.9 55.4 1.7 8.3 5.3 0.8 15.4 3.7 4.1 1.0 3.4 2.7 12.9 38.1 27.7 10.2 34.7 1.3 3.9 16.4 15.8 3.5 8.4 6.1 7.9 1.0 13.6 3.3 7.6 3.8 7.1 4.2 5.7 0.9 15.8 4.8 9.1 2.6 3.3 10.4 4.6 4.2 3.4 1.0 5.4 2.2 0.7 1.5 12.9 0.5 0.4 0.8 0.9 0.1 2.8 6.7 14.0 12.2 4.4 1.1 1.7 6.6 3.1 12.0 9.4 2.5 0.2 18.2 6.8 3.2 1.4 18.9 0.1 10.3 5.5 37.5 3.1 9.6 13.6 2.8 12.4 15.3 0.4 1.2 5.8 8.6 5.5 11.1 11.0 10.7 2.3 25.4 20.8 7.1 16.5 19.8 10.1 13.4 5.2 0.3 32.6 20.6 6.3 5.3 11.6 1.3 9.9 3.2 10.4 13.0 11.0 13.2 11.4 14.5 19.4 9.8 4.0 13.1 0.0 0.3 0.5 0.9 0.4 0.1 1.5 0.3 0.6 0.6 1.4 0.3 0.1 0.4 0.8 0.2 12.9 0.3 0.1 43.5 32.0 24.9 50.6 38.1 27.7 16.4 15.8 13.6 4.6 PEPD ENSG00000124299 "Peptidase D" P12955 19 33386950-33521794 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Collagen degradation" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 92.9;kidney: 106.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015599, HPA072045" Enhanced Approved Nucleoplasm 1000000000 Nucleoplasm "HPA015599: AB_1855192, HPA072045: " "unprognostic (1.39e-1)" "unprognostic (2.62e-2)" "unprognostic (2.27e-1)" "unprognostic (4.01e-2)" "unprognostic (2.98e-1)" "unprognostic (6.77e-2)" "unprognostic (2.82e-1)" "unprognostic (3.64e-2)" "unprognostic (3.96e-1)" "unprognostic (5.10e-2)" "unprognostic (1.11e-2)" "unprognostic (1.99e-1)" "prognostic favourable (6.50e-9)" "unprognostic (4.38e-2)" "unprognostic (1.99e-1)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" 23.5 17.2 9.8 8.9 10.4 4.1 21.8 7.6 14.9 9.8 60.1 18.7 6.9 58.1 14.3 11.5 14.9 9.6 13.6 8.0 10.8 9.1 106.0 48.6 11.1 10.6 16.0 7.7 12.6 9.0 9.6 12.5 10.4 13.0 9.2 6.6 13.3 9.6 9.0 9.7 11.4 92.9 10.4 17.4 13.4 9.3 8.4 11.5 8.4 15.0 9.7 10.6 11.9 11.9 17.1 32.3 27.5 39.1 16.8 25.8 32.6 13.2 35.9 10.6 17.0 45.2 17.4 24.5 11.7 24.1 15.0 17.1 31.2 11.6 5.4 17.6 29.5 3.4 15.2 9.6 12.4 15.2 15.0 34.3 7.3 31.7 30.9 9.9 41.6 21.4 9.1 13.7 8.5 20.0 6.5 15.6 16.3 16.1 7.6 3.3 14.6 14.6 15.0 14.4 14.9 13.0 34.9 13.0 33.4 21.9 10.8 17.7 7.5 10.8 16.7 14.5 15.7 18.8 13.6 14.3 21.2 4.7 15.5 14.4 20.6 27.5 36.1 2.5 25.8 39.1 22.6 17.1 25.7 23.8 32.3 16.3 16.9 19.6 1.9 16.8 27.2 9.9 23.6 32.6 9.8 10.4 7.6 14.9 10.8 9.1 16.0 7.7 13.0 11.5 PFKFB1 PFRX ENSG00000158571 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" P16118 X 54932961-54998534 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 24.2;liver: 24.4;skeletal muscle: 48.3" "Group enriched" "Detected in some" 4 "ASC diff: 13.6;Hep G2: 5.4" "Cancer enriched" "Detected in some" 11 "liver cancer: 7.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "MAIT T-cell: 2.1" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "unprognostic (2.51e-1)" "unprognostic (2.39e-2)" "unprognostic (1.17e-2)" "unprognostic (4.38e-3)" "unprognostic (1.64e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "unprognostic (3.33e-1)" "unprognostic (3.26e-3)" "unprognostic (2.88e-1)" "unprognostic (5.36e-3)" "unprognostic (5.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.16e-4)" "unprognostic (1.96e-3)" 24.2 0.2 0.1 1.6 0.1 0.1 13.1 0.1 0.2 0.1 1.7 0.1 0.1 0.0 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.4 24.4 0.1 1.6 0.1 0.1 0.1 0.6 0.2 0.2 0.1 0.1 0.3 0.2 0.1 1.3 0.1 48.3 0.3 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.5 8.3 0.6 0.2 2.0 1.5 0.1 0.0 0.7 1.3 2.1 0.3 0.3 0.2 0.4 0.6 13.6 0.3 1.0 0.0 0.1 0.2 0.0 0.8 0.2 0.6 0.2 0.1 0.5 0.1 0.3 0.4 0.4 1.1 0.4 0.1 5.4 0.0 0.1 0.5 0.2 0.6 0.1 0.4 0.0 0.1 2.1 0.2 0.7 0.6 0.3 0.3 0.3 0.5 0.2 0.1 0.0 0.4 0.4 0.2 0.5 1.5 0.2 0.4 0.0 0.1 0.1 0.5 0.4 0.2 1.1 1.7 0.4 0.2 0.4 0.1 0.0 0.0 0.0 0.2 0.7 2.1 1.5 0.2 0.0 0.0 0.8 0.0 0.8 0.0 1.3 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 PFKFB2 ENSG00000123836 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" O60825 1 207034366-207081024 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 13.9;plasmacytoid DC: 16.7" "Group enriched" "Detected in many" 8 "dendritic cells: 16.7;granulocytes: 13.9" "Low region specificity" "Detected in all" "HPA049975, HPA063575" Uncertain Enhanced Nucleoplasm Nucleoplasm "HPA049975: , HPA063575: " "unprognostic (1.30e-1)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.75e-2)" "unprognostic (2.27e-1)" "unprognostic (3.76e-2)" "unprognostic (9.96e-3)" "unprognostic (9.74e-2)" "unprognostic (7.27e-2)" "unprognostic (2.27e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" "prognostic favourable (3.23e-7)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" "prognostic unfavourable (8.63e-4)" "unprognostic (1.86e-2)" 3.3 6.1 9.8 5.8 16.6 15.7 5.1 2.1 14.6 7.3 16.0 19.5 5.3 23.2 4.0 9.1 7.7 4.5 9.1 22.8 14.1 7.7 22.0 3.6 10.9 5.3 13.4 15.1 4.3 11.9 6.2 27.5 3.0 25.3 3.9 18.1 22.4 6.3 3.5 34.9 6.4 18.7 4.0 17.4 12.5 10.7 6.1 15.1 6.5 38.4 8.8 5.0 3.4 3.6 1.6 16.7 13.9 1.9 1.1 0.4 0.4 9.5 4.2 2.8 4.8 5.7 2.8 4.6 1.3 1.7 2.4 1.3 10.2 13.8 1.7 2.2 2.1 13.6 2.0 5.1 1.4 0.3 2.1 13.5 10.6 3.8 4.8 0.0 9.5 4.1 7.8 2.3 12.9 0.5 9.2 0.1 1.3 2.9 2.3 0.4 3.8 6.4 0.0 0.0 0.2 3.3 9.9 4.4 2.7 8.9 15.1 11.2 10.3 1.1 0.2 0.0 5.2 7.3 1.2 4.4 4.4 0.9 5.9 0.0 2.6 1.0 0.9 13.9 0.2 1.9 0.3 1.3 0.1 0.3 0.8 1.6 0.3 0.4 2.6 1.1 1.3 16.7 0.0 0.4 9.8 16.6 2.1 14.6 14.1 7.7 13.4 15.1 25.3 15.1 PFKFB3 ENSG00000170525 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" Q16875 10 6144934-6254644 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 105.6;skeletal muscle: 135.7" "Cell line enhanced" "Detected in many" "A549: 71.1;RPTEC TERT1: 44.9;T-47d: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 20.5" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008266, CAB020795, HPA043889" Uncertain Enhanced Nucleoplasm Nucleoplasm "CAB020795: , HPA008266: AB_1855239, HPA043889: " "unprognostic (1.61e-1)" "unprognostic (5.08e-3)" "unprognostic (2.89e-2)" "unprognostic (6.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (1.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (3.30e-2)" "unprognostic (7.34e-2)" "prognostic unfavourable (1.87e-7)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" 105.6 9.0 16.4 25.7 17.9 77.0 43.4 8.5 29.4 6.6 8.8 29.1 10.6 7.4 9.4 6.3 13.0 14.4 22.4 5.7 16.6 13.2 22.1 11.2 15.1 12.1 19.2 12.9 8.0 8.1 4.0 10.2 7.5 20.7 5.4 3.8 19.3 9.1 20.0 135.7 11.8 6.9 6.5 36.0 12.4 6.7 4.6 16.8 3.3 2.9 4.7 10.3 10.3 10.1 1.5 3.6 20.5 7.1 0.8 4.7 2.9 5.1 71.1 5.6 4.5 21.4 2.7 3.0 7.6 5.4 5.6 8.8 3.3 18.8 8.8 5.0 3.3 16.6 6.0 12.0 6.5 10.4 4.2 5.2 3.6 1.2 1.8 5.0 7.9 1.9 4.0 9.7 2.3 10.9 3.8 3.3 4.5 8.4 3.5 4.7 5.5 5.0 8.0 2.7 3.4 44.9 2.6 5.4 2.2 5.5 6.0 10.8 46.8 6.0 13.7 5.9 5.4 0.7 9.1 6.8 2.3 8.0 16.3 5.9 9.0 2.2 5.6 5.5 1.8 7.1 4.7 1.5 3.4 2.3 3.6 1.4 2.5 2.4 20.5 0.8 4.1 2.2 3.2 2.9 16.4 17.9 8.5 16.9 16.6 13.2 19.2 12.9 20.7 16.8 PFKFB4 ENSG00000114268 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4" Q16877 3 48517684-48562015 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.0" "Cell line enhanced" "Detected in many" "U-87 MG: 37.1;WM-115: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.5;eosinophil: 11.4;intermediate monocyte: 7.3;neutrophil: 21.6;non-classical monocyte: 12.2" "Group enriched" "Detected in many" 6 "granulocytes: 21.6;monocytes: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047719, HPA066058" Uncertain Approved Nucleoli Nucleoli "HPA047719: , HPA066058: " "unprognostic (7.60e-2)" "prognostic unfavourable (3.04e-4)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (3.90e-3)" "unprognostic (7.96e-2)" "unprognostic (1.72e-6)" "unprognostic (1.65e-1)" "unprognostic (3.75e-2)" "unprognostic (6.78e-2)" "unprognostic (3.78e-2)" "unprognostic (7.13e-2)" "prognostic unfavourable (3.91e-8)" "unprognostic (2.04e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-3)" "unprognostic (3.35e-2)" 2.0 2.2 4.0 3.9 4.9 12.7 2.1 6.3 6.3 2.6 17.1 8.6 3.0 17.8 2.1 18.5 6.4 1.5 1.8 1.4 4.2 5.2 3.6 1.7 3.8 6.3 7.4 2.7 3.5 18.9 4.1 5.1 9.5 6.9 3.3 3.5 3.3 2.5 2.0 4.8 3.3 24.0 2.5 5.3 10.0 1.2 26.0 5.2 0.4 1.6 3.6 2.6 4.9 4.2 0.2 2.7 21.6 12.2 0.2 0.5 2.1 5.1 1.6 3.7 3.4 1.2 1.8 7.2 2.6 4.4 5.3 12.8 2.6 1.8 2.2 2.5 2.0 1.5 1.5 4.4 4.7 1.5 1.2 5.2 3.3 2.8 1.0 0.9 2.3 1.9 6.8 8.5 0.8 1.3 1.7 1.9 4.2 1.1 0.3 7.2 2.3 3.4 0.4 1.8 2.4 2.0 4.8 1.0 2.3 2.8 1.2 10.1 2.8 2.2 0.4 5.4 2.2 0.7 15.6 8.9 1.9 1.3 37.1 1.9 32.3 0.0 6.5 11.4 0.2 7.3 0.1 0.2 0.3 0.0 2.7 0.1 0.5 0.1 21.6 0.2 12.2 0.3 0.0 2.1 4.0 4.9 6.3 6.3 4.2 5.2 7.4 2.7 6.9 5.2 PGA3 ENSG00000229859 "Pepsinogen 3, group I (pepsinogen A)" P0DJD8 11 61203307-61213098 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "stomach 1: 1048.8" "Group enriched" "Detected in some" 5 "HMC-1: 13.4;THP-1: 4.4" "Cancer enriched" "Detected in single" 498 "stomach cancer: 24.8" "Region enriched" "Detected in single" 15 "cerebral cortex: 4.8" "Cell type enhanced" "Detected in many" "intermediate monocyte: 6.7" "Lineage enriched" "Detected in many" 4 "monocytes: 6.7" "CAB026358, HPA046875" Enhanced "Secreted to digestive system" "CAB026358: , HPA046875: " "unprognostic (6.39e-2)" "unprognostic (1.11e-1)" 0.3 0.1 0.0 0.2 0.3 0.0 0.3 0.0 4.8 0.2 0.4 19.9 0.0 0.1 0.1 0.5 36.8 0.2 0.0 0.4 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.4 17.7 0.0 0.0 0.2 0.0 0.2 0.0 0.1 2.0 0.1 0.1 0.0 0.0 0.7 0.0 1.4 1048.8 0.1 0.0 0.0 0.1 3.8 0.0 0.1 0.0 0.3 0.3 1.1 6.7 0.5 1.5 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 13.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.3 0.4 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.5 4.3 0.2 1.5 6.7 0.9 0.2 0.5 1.4 0.3 0.3 0.2 1.4 1.1 0.5 1.7 0.2 0.1 3.0 0.0 0.3 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 PGA4 ENSG00000229183 "Pepsinogen 4, group I (pepsinogen A)" P0DJD7 11 61222216-61231927 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 120 "stomach 1: 924.0" "Group enriched" "Detected in some" 8 "BJ hTERT+: 17.2;THP-1: 8.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "classical monocyte: 7.6;intermediate monocyte: 5.9;non-classical monocyte: 2.1" "Lineage enriched" "Detected in single" 23 "monocytes: 7.6" HPA046875 Supported "Secreted to digestive system" "HPA046875: " "unprognostic (2.22e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 924.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 7.6 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 1.4 PGA5 ENSG00000256713 "Pepsinogen 5, group I (pepsinogen A)" P0DJD9 11 61241042-61251448 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "stomach 1: 296.9" "Cell line enriched" "Detected in some" 14 "BJ hTERT+: 25.1" "Cancer enriched" "Detected in some" 12 "stomach cancer: 15.0" "Group enriched" "Detected in some" 50 "classical monocyte: 3.4;intermediate monocyte: 7.7;non-classical monocyte: 3.7" "Lineage enriched" "Detected in single" 77 "monocytes: 7.7" HPA046875 Supported "Secreted to digestive system" "HPA046875: " "unprognostic (1.36e-3)" "unprognostic (2.98e-2)" "unprognostic (5.83e-3)" "unprognostic (2.11e-1)" "unprognostic (4.22e-1)" "unprognostic (4.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (7.10e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 296.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.6 PGAM5 "BXLBv68, MGC5352" ENSG00000247077 "PGAM family member 5, mitochondrial serine/threonine protein phosphatase" Q96HS1 12 132710819-132722734 "Enzymes, Predicted intracellular proteins" Necrosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036978, HPA036979, CAB068215" Enhanced Supported Mitochondria "Intracellular and membrane" Mitochondria "CAB068215: , HPA036978: AB_10964347, HPA036979: AB_10960559" "unprognostic (9.57e-2)" "unprognostic (2.00e-2)" "unprognostic (3.83e-2)" "unprognostic (3.11e-2)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "prognostic unfavourable (1.13e-6)" "unprognostic (3.32e-2)" "unprognostic (1.47e-1)" "unprognostic (5.67e-2)" "unprognostic (1.23e-1)" "unprognostic (6.92e-2)" "unprognostic (6.42e-3)" "unprognostic (1.63e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (5.53e-2)" 12.2 16.5 11.7 14.3 14.0 12.5 18.6 14.6 22.1 8.4 13.9 8.3 9.9 13.6 10.4 9.9 22.0 11.5 13.4 22.6 14.2 12.1 13.9 26.3 8.5 17.6 9.9 11.8 11.9 30.2 8.1 9.6 10.3 10.4 10.1 10.4 8.5 16.0 11.4 27.4 15.2 12.0 10.2 7.5 13.0 11.7 13.6 5.1 17.6 16.3 17.4 14.5 11.6 12.9 4.0 6.7 7.7 3.1 3.3 3.7 1.4 19.1 36.9 7.9 22.2 5.6 4.5 18.5 9.9 6.1 16.7 9.4 46.0 11.1 24.8 18.3 8.5 16.8 37.0 18.6 6.8 12.2 29.1 29.7 17.3 23.9 12.7 28.1 17.4 5.5 13.7 19.4 20.9 12.1 37.2 10.3 6.5 34.7 38.1 28.1 29.9 26.2 29.2 8.8 19.8 10.8 26.6 29.0 16.3 17.1 24.1 10.6 30.4 15.6 10.4 8.5 18.5 17.0 24.0 21.5 31.5 35.6 11.0 23.1 14.2 7.7 2.4 0.7 2.5 2.5 3.7 3.6 2.9 2.8 2.0 4.0 2.9 3.6 2.0 3.3 3.1 6.7 2.0 1.4 11.7 14.0 14.6 22.1 14.2 12.1 9.9 11.8 10.4 5.1 PGC ENSG00000096088 Progastricsin P20142 6 41736711-41754109 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Digestion "Aspartyl protease, Hydrolase, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "ductus deferens: 249.6;pancreas: 798.6;stomach 1: 963.7" "Cell line enriched" "Detected in some" 13 "Hep G2: 73.2" "Cancer enhanced" "Detected in many" "stomach cancer: 1050.3" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "intermediate monocyte: 1.9" "Lineage enriched" "Detected in single" 7 "monocytes: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031717, HPA031718" Enhanced Approved Nucleoplasm "Secreted to digestive system" Nucleoplasm "HPA031717: AB_10670130, HPA031718: AB_10610148" "unprognostic (9.18e-2)" "unprognostic (1.87e-1)" "unprognostic (9.83e-2)" "unprognostic (2.27e-1)" "unprognostic (7.18e-2)" "unprognostic (2.74e-1)" "unprognostic (1.47e-1)" "unprognostic (8.50e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "unprognostic (8.74e-2)" 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.3 0.1 3.0 249.6 41.7 0.1 0.0 3.3 0.3 16.8 0.1 0.1 0.1 0.1 0.3 139.4 0.0 0.1 0.0 0.1 798.6 0.0 0.1 0.0 0.1 2.3 0.0 0.0 0.1 35.9 0.1 0.1 0.1 0.0 0.1 0.1 963.7 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.2 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 1.7 0.0 0.8 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 PGGHG "ATHL1, FLJ22635" ENSG00000142102 "Protein-glucosylgalactosylhydroxylysine glucosidase" Q32M88 11 289135-296107 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "pancreas: 148.7" "Cell line enhanced" "Detected in many" "U-266/70: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA039383, HPA058829" Uncertain Enhanced Cytosol Cytosol "HPA039383: AB_10796225, HPA058829: " "unprognostic (1.40e-3)" "unprognostic (2.18e-1)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (1.36e-2)" "unprognostic (5.83e-2)" "unprognostic (7.95e-3)" "unprognostic (2.77e-2)" "unprognostic (2.16e-2)" "unprognostic (2.14e-2)" "unprognostic (2.71e-2)" "unprognostic (3.45e-1)" "unprognostic (1.92e-3)" "unprognostic (2.85e-3)" "unprognostic (1.09e-2)" "unprognostic (1.22e-1)" "prognostic favourable (5.12e-4)" 5.6 1.8 6.0 16.7 9.3 6.3 10.5 2.9 7.7 12.7 5.6 3.3 10.4 21.1 6.9 14.9 5.6 8.4 8.3 4.4 6.3 1.7 14.8 17.0 15.7 24.6 7.6 2.5 3.5 148.7 2.6 3.6 3.4 8.0 8.5 3.0 7.1 8.9 21.8 5.6 2.4 23.2 5.2 10.1 24.2 4.7 2.3 7.5 6.3 18.0 6.4 15.4 7.3 8.7 2.3 2.5 4.9 4.2 6.9 8.5 2.7 3.4 3.7 7.0 7.7 2.8 2.5 5.3 2.7 2.2 1.6 1.4 3.2 9.8 0.0 3.5 3.3 2.1 0.6 1.2 0.2 8.3 2.6 1.6 2.4 4.2 3.6 0.2 15.1 9.4 1.0 0.6 0.4 5.3 6.5 10.5 0.8 4.9 14.3 7.6 5.4 0.6 13.5 1.4 4.8 3.7 1.2 0.0 1.6 1.0 5.1 4.7 3.7 1.9 4.9 3.3 4.7 1.0 0.3 22.8 0.6 3.6 0.5 2.7 3.8 1.5 0.9 1.2 8.5 4.2 7.2 2.1 1.3 4.7 0.6 2.3 3.1 6.1 4.9 6.9 3.2 2.5 0.2 2.7 6.0 9.3 2.9 7.7 6.3 1.7 7.6 2.5 8.0 7.5 PGLS 6PGL ENSG00000130313 6-phosphogluconolactonase O95336 19 17511629-17521288 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040744, HPA042032" Approved Supported Nucleoplasm,Cytosol 10000000 Nucleoplasm Cytosol "HPA040744: AB_2677111, HPA042032: AB_2677809" "unprognostic (3.68e-2)" "unprognostic (8.98e-3)" "unprognostic (1.25e-1)" "unprognostic (9.64e-3)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (3.55e-3)" "unprognostic (2.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (2.16e-1)" "unprognostic (1.30e-1)" "unprognostic (4.75e-3)" "unprognostic (2.39e-1)" "unprognostic (1.99e-1)" "unprognostic (5.05e-2)" "unprognostic (9.26e-3)" 27.3 31.5 15.6 23.6 13.9 29.3 33.7 9.0 20.1 23.8 29.5 16.0 17.9 21.9 16.6 18.7 38.0 25.9 27.8 18.5 13.9 11.6 25.9 42.7 27.5 60.0 14.3 11.8 32.0 42.1 19.1 16.4 26.5 10.9 23.5 13.5 16.8 31.5 20.7 10.9 27.2 30.8 13.3 16.8 31.4 20.8 15.8 12.2 46.6 26.7 19.2 27.6 18.5 21.6 17.6 46.4 45.8 44.5 17.4 14.9 22.4 18.6 16.8 10.6 7.2 16.2 27.0 20.3 12.8 20.9 12.9 16.6 8.0 28.3 20.7 14.4 20.0 12.9 5.9 20.0 3.9 10.3 23.2 9.7 7.8 14.3 27.9 10.3 10.8 31.7 27.7 7.7 23.2 17.3 11.0 5.1 15.8 20.5 22.6 29.0 14.1 70.6 15.3 6.8 13.1 17.4 15.1 13.5 16.2 8.2 9.1 18.0 13.2 18.7 16.2 13.4 3.7 26.7 7.2 9.0 6.3 8.8 19.1 26.5 13.1 15.2 40.8 45.8 14.9 44.5 12.1 16.4 13.2 13.2 46.4 17.6 12.5 12.6 39.6 17.4 41.5 34.4 14.0 22.4 15.6 13.9 9.0 20.1 13.9 11.6 14.3 11.8 10.9 12.2 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 95.8" "Group enriched" "Detected in some" 6 "MCF7: 10.6;T-47d: 10.7" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.6;monocytes: 7.1;T-cells: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" 160000000000 "Cell Junctions" "CAB033468: AB_1127187, HPA046311: , HPA075237: " "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 3.6 7.1 0.6 3.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.7 0.0 0.0 0.2 0.0 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 3.6 0.7 0.3 2.6 2.4 2.5 0.3 1.6 1.3 0.2 0.0 3.6 3.7 2.5 0.6 7.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGP ENSG00000184207 "Phosphoglycolate phosphatase" A6NDG6 16 2211997-2214807 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 40.7" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043096, HPA046739" Approved Approved "Nuclear bodies" 46000 "Nuclear bodies" "HPA043096: AB_2678311, HPA046739: AB_2679779" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (2.36e-2)" "unprognostic (7.23e-2)" "unprognostic (2.12e-3)" "unprognostic (1.76e-1)" "unprognostic (5.75e-3)" "unprognostic (5.87e-2)" "unprognostic (7.90e-2)" "unprognostic (4.43e-3)" "unprognostic (6.50e-2)" "unprognostic (9.04e-2)" "prognostic favourable (7.05e-4)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "prognostic favourable (6.42e-4)" 5.7 7.2 10.9 7.3 12.5 9.2 3.6 31.4 21.4 3.9 6.7 4.8 7.3 7.9 4.7 6.5 3.6 3.7 4.4 15.6 11.4 9.8 6.1 5.5 6.2 7.5 9.6 12.8 2.5 6.6 8.7 6.1 6.9 17.8 5.3 5.3 4.7 6.2 6.8 40.7 5.6 7.5 4.9 6.0 8.0 6.7 23.0 7.4 5.9 8.8 7.9 5.0 4.2 2.6 1.8 1.9 6.1 3.4 0.3 2.2 0.4 9.1 15.0 10.7 10.1 4.4 3.5 20.5 10.8 5.2 10.0 10.3 23.3 11.6 7.0 10.6 5.0 15.5 7.5 9.2 4.4 9.4 20.8 7.0 22.9 10.5 3.0 12.4 11.6 4.2 4.1 9.3 3.5 6.4 12.7 7.4 5.5 25.0 13.9 20.2 14.1 14.2 22.8 9.3 15.7 8.2 5.8 14.3 8.7 9.6 18.1 7.4 13.4 14.5 6.3 10.3 13.5 9.2 10.7 17.6 7.6 9.9 3.4 11.0 8.0 0.0 2.3 6.1 2.2 3.4 0.3 0.7 1.3 1.6 1.6 1.8 0.8 1.4 1.4 0.3 3.1 1.9 1.3 0.4 10.9 12.5 31.4 21.4 11.4 9.8 9.6 12.8 17.8 7.4 PGPEP1 "Pcp, PGP, PGP-I, PGPI" ENSG00000130517 "Pyroglutamyl-peptidase I" Q9NXJ5 19 18340587-18369950 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035368, HPA055277" Approved Approved "Golgi apparatus" "Golgi apparatus" "HPA035368: AB_10601388, HPA055277: " "unprognostic (9.52e-3)" "unprognostic (1.37e-2)" "unprognostic (6.95e-2)" "unprognostic (5.74e-3)" "unprognostic (5.29e-2)" "unprognostic (6.60e-2)" "unprognostic (1.96e-2)" "unprognostic (2.11e-3)" "prognostic favourable (6.80e-4)" "unprognostic (2.79e-2)" "prognostic favourable (1.71e-4)" "unprognostic (4.81e-3)" "prognostic favourable (3.71e-8)" "unprognostic (1.12e-2)" "unprognostic (1.66e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-3)" 11.0 18.6 14.8 10.1 14.9 12.4 10.7 8.1 12.5 13.9 23.3 14.8 25.3 23.6 8.2 16.0 6.3 10.0 16.7 20.6 18.2 15.4 29.9 29.7 9.4 11.4 17.8 7.3 13.2 26.6 15.1 17.1 7.5 12.5 13.4 17.2 13.7 22.8 23.6 25.2 3.6 33.6 12.1 25.5 16.2 15.4 4.2 15.6 8.6 11.5 7.4 7.0 12.8 10.0 3.9 3.3 17.6 6.1 4.3 4.9 3.6 4.7 7.5 6.2 6.3 7.9 6.2 7.6 5.6 8.8 3.9 5.8 5.3 10.1 7.2 9.5 9.2 1.2 2.4 1.3 2.2 8.5 2.7 7.9 7.5 14.8 11.2 4.6 33.2 6.3 2.8 3.0 0.5 5.8 14.5 11.0 3.2 7.6 4.7 3.7 6.3 2.3 0.0 2.3 6.4 4.2 7.4 2.2 3.5 1.1 0.6 10.0 2.8 9.5 8.9 4.5 3.0 5.8 2.4 13.7 6.5 4.3 12.0 13.2 4.1 17.6 5.4 7.1 4.9 5.4 2.8 2.0 3.4 4.4 3.3 3.9 4.3 4.0 3.1 4.3 6.1 2.2 3.8 3.6 14.8 14.9 8.1 12.5 18.2 15.4 17.8 7.3 12.5 15.6 PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715450-62980433 "Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 7.7;T-reg: 2.4" "Group enriched" "Detected in many" 7 "granulocytes: 7.7;T-cells: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Uncertain "Intracellular and membrane" "HPA020200: " "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.07e-2)" "unprognostic (5.57e-2)" "unprognostic (5.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.10e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "prognostic favourable (5.35e-8)" "unprognostic (1.52e-1)" "unprognostic (3.49e-2)" "unprognostic (8.13e-2)" "unprognostic (8.25e-2)" 5.8 10.6 22.1 2.3 34.1 7.4 7.4 8.3 29.6 4.3 6.0 48.0 0.9 6.2 4.4 2.5 6.1 4.0 4.9 3.0 22.4 12.3 4.0 18.5 3.4 3.0 44.4 13.8 5.5 8.0 9.6 5.6 6.3 20.6 5.0 6.7 4.4 11.2 4.5 3.9 9.1 5.5 4.0 18.6 2.0 5.6 11.5 44.8 2.3 5.6 1.6 4.1 5.6 3.2 0.6 0.7 7.7 0.2 0.6 2.4 0.1 8.9 3.4 13.8 4.6 2.3 2.0 10.8 2.7 2.4 5.4 5.5 7.3 5.4 6.0 1.6 4.0 11.0 7.1 4.2 6.9 18.6 5.9 2.0 3.7 13.4 3.3 3.0 1.0 2.1 2.8 5.7 5.3 3.8 5.1 12.2 5.1 2.0 2.2 2.6 5.6 3.3 21.4 7.8 7.2 3.0 11.6 6.4 2.6 2.9 6.7 5.5 2.9 8.8 4.8 4.4 2.1 2.6 6.2 1.4 0.7 7.1 2.6 3.5 3.3 0.0 0.2 0.1 0.7 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.4 0.1 7.7 0.6 0.2 0.3 2.4 0.1 22.1 34.1 8.3 21.1 22.4 12.3 44.4 13.8 20.6 44.8 PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 29.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048598 Approved Approved Vesicles Vesicles "HPA048598: " "unprognostic (5.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-1)" "unprognostic (1.97e-4)" "unprognostic (3.08e-2)" "unprognostic (8.85e-3)" "unprognostic (6.41e-2)" "unprognostic (4.92e-2)" "unprognostic (8.46e-3)" "unprognostic (8.27e-2)" 6.4 4.7 12.5 7.0 10.9 8.1 8.4 17.4 14.9 4.4 16.6 4.6 4.3 15.8 5.8 4.9 2.7 4.7 4.1 4.6 11.7 9.0 5.4 4.9 4.8 5.0 6.2 14.9 7.2 4.9 10.2 7.3 4.3 12.6 4.7 17.8 13.2 2.9 5.7 5.3 3.0 29.9 7.0 7.6 3.9 4.2 10.8 4.7 1.0 9.9 1.1 4.9 4.7 9.8 2.4 2.2 1.2 0.7 3.5 1.5 0.4 4.8 6.4 7.0 7.8 5.6 6.8 4.0 7.3 6.6 10.6 8.6 5.9 1.6 9.6 2.9 12.0 10.3 10.1 3.7 13.7 3.4 5.5 2.7 5.5 3.8 4.4 2.3 4.2 5.0 2.2 15.0 4.9 3.9 2.4 2.6 7.3 10.2 3.1 1.8 5.5 1.7 5.1 6.2 3.1 5.0 3.7 6.1 3.2 15.7 4.3 2.5 5.3 1.3 5.4 10.7 7.7 4.5 6.0 6.1 4.2 10.0 6.6 1.9 2.3 0.8 0.5 0.2 1.0 0.7 0.9 2.4 0.8 1.5 0.6 1.6 1.1 0.9 1.2 3.5 0.7 2.2 1.3 0.4 12.5 10.9 17.4 14.9 11.7 9.0 6.2 14.9 12.6 4.7 PHOSPHO1 ENSG00000173868 "Phosphoethanolamine/phosphocholine phosphatase" Q8TCT1 17 49223362-49230766 "Enzymes, Predicted intracellular proteins" "Mineral balance" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 80.0;testis: 52.3" "Cell line enhanced" "Detected in some" "Daudi: 9.2;EFO-21: 6.2;HDLM-2: 6.5" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 4 "cerebral cortex: 10.2;pons and medulla: 8.2" "Group enriched" "Detected in some" 171 "eosinophil: 30.6;neutrophil: 80.0" "Lineage enriched" "Detected in single" 248 "granulocytes: 80.0" "Low region specificity" "Detected in all" HPA065025 Approved "Plasma membrane,Actin filaments" "Actin filaments" "Plasma membrane" "HPA065025: " "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (7.53e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-1)" "unprognostic (4.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-2)" "unprognostic (2.04e-1)" "unprognostic (6.88e-2)" "unprognostic (1.02e-2)" "unprognostic (2.88e-1)" "unprognostic (2.03e-1)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (1.87e-1)" 2.5 1.3 1.1 2.9 1.9 15.3 0.7 1.0 10.2 0.6 0.6 0.2 0.2 2.5 0.9 2.7 0.9 1.3 2.1 1.0 1.7 1.3 1.0 0.9 2.5 2.0 2.1 1.5 1.1 1.0 0.1 0.8 7.6 8.2 0.9 0.0 1.6 0.9 0.5 2.2 1.1 2.6 0.3 1.5 12.6 0.7 52.3 0.1 0.0 0.8 0.1 0.1 1.4 1.3 0.0 0.0 80.0 0.3 0.0 0.0 0.1 0.0 1.2 0.0 2.1 0.1 0.2 0.0 0.3 0.4 0.0 0.2 2.9 0.0 9.2 6.2 0.0 0.0 1.7 0.5 0.1 6.5 0.2 1.2 1.2 0.4 0.0 0.0 1.1 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 1.7 1.8 3.5 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.2 3.7 0.5 3.0 2.0 0.0 0.3 0.3 0.6 2.7 3.5 0.3 0.0 0.1 30.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.0 0.0 0.3 0.0 0.0 0.1 1.1 1.9 1.0 10.2 1.7 1.3 2.1 1.5 8.2 0.1 PHOSPHO2 MGC22679 ENSG00000144362 "Phosphatase, orphan 2" Q8TCD6 2 169694454-169701708 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034726, HPA034727" Uncertain Approved Vesicles Vesicles "HPA034726: AB_10602191, HPA034727: " "unprognostic (1.98e-1)" "unprognostic (1.22e-1)" "unprognostic (7.56e-2)" "unprognostic (1.39e-3)" "unprognostic (1.30e-2)" "unprognostic (2.26e-1)" "prognostic unfavourable (3.82e-6)" "unprognostic (4.31e-2)" "unprognostic (2.11e-2)" "unprognostic (5.19e-2)" "unprognostic (1.40e-1)" "unprognostic (2.31e-1)" "prognostic favourable (9.53e-4)" "unprognostic (4.10e-1)" "unprognostic (2.60e-1)" "unprognostic (6.12e-2)" "unprognostic (7.53e-2)" 8.7 4.0 9.0 5.7 9.7 3.3 14.2 14.2 7.8 8.4 8.2 5.8 6.3 8.2 8.6 5.9 4.6 8.1 6.2 5.7 6.7 5.5 7.5 5.0 4.3 3.6 6.0 9.1 8.2 8.9 10.9 21.3 3.9 7.8 17.4 7.8 6.4 10.5 7.8 6.4 5.2 7.9 6.2 9.7 3.4 6.3 25.4 8.0 5.5 13.0 3.9 3.9 9.1 5.7 8.8 4.6 1.5 1.0 10.5 5.7 1.8 5.6 1.6 4.1 5.5 7.8 2.5 16.0 2.5 1.7 3.8 4.3 5.5 4.4 5.5 5.6 1.8 4.4 5.4 3.0 3.2 8.1 6.3 5.5 4.8 9.5 5.1 4.5 5.0 4.5 5.7 4.4 5.9 3.4 9.1 5.7 2.4 5.2 3.1 5.8 5.5 2.1 3.2 2.5 4.3 6.1 17.0 17.2 5.9 5.3 2.8 5.9 7.4 2.7 2.0 4.2 4.0 4.0 2.7 5.5 5.1 4.9 5.0 2.7 4.5 0.0 0.9 1.1 3.9 1.0 5.5 6.8 4.3 3.7 1.0 8.8 5.7 5.6 1.5 10.5 0.9 4.6 4.4 1.8 9.0 9.7 14.2 7.8 6.7 5.5 6.0 9.1 7.8 8.0 PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013584, HPA020952" Approved Approved "Nuclear bodies,Cytosol" 430000 Cytosol "Nuclear bodies" "CAB013584: , HPA020952: AB_1855331" "unprognostic (7.34e-2)" "unprognostic (9.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.30e-1)" "unprognostic (4.64e-2)" "unprognostic (1.69e-2)" "unprognostic (3.23e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-3)" "unprognostic (5.85e-2)" "unprognostic (9.66e-3)" "unprognostic (1.11e-2)" "unprognostic (2.01e-1)" "unprognostic (3.95e-2)" "unprognostic (8.49e-2)" 15.8 26.4 31.5 12.1 28.0 11.7 15.3 14.7 27.2 19.2 15.7 18.5 13.7 14.7 11.2 21.7 13.7 21.1 14.2 59.1 22.7 19.3 18.4 12.6 12.1 12.7 27.0 21.0 13.7 46.5 15.6 21.2 14.7 20.8 20.2 11.6 14.1 30.5 22.6 86.0 9.2 16.3 16.9 24.3 10.3 13.4 13.8 18.6 7.5 20.7 19.8 10.4 12.0 9.8 24.9 48.8 3.3 35.4 20.0 24.3 32.1 7.1 52.2 29.8 19.0 19.3 35.0 43.8 16.7 21.3 20.4 18.1 19.0 16.3 15.2 20.3 20.6 19.0 6.5 37.7 6.4 13.6 13.2 4.8 34.3 41.7 24.0 9.5 19.6 43.6 31.0 11.7 14.1 26.7 11.5 14.2 31.6 40.7 13.9 20.1 23.6 22.5 11.5 13.0 25.1 32.2 11.9 14.6 13.9 17.9 21.1 8.7 16.0 26.5 21.7 42.6 13.2 11.8 15.4 9.4 9.1 9.3 24.1 6.9 25.5 2.9 35.4 3.3 24.3 34.2 20.9 24.9 21.1 21.9 37.5 16.5 15.0 21.3 1.7 20.0 24.0 48.8 22.9 32.1 31.5 28.0 14.7 27.2 22.7 19.3 27.0 21.0 20.8 18.6 PIF1 "C15orf20, FLJ22692" ENSG00000140451 "PIF1 5'-to-3' DNA helicase" Q9H611 15 64815632-64825668 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.3" "Low cell line specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 10.2" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "T-reg: 3.2" "Lineage enriched" "Detected in single" 5 "T-cells: 3.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB018701 Supported Supported Nucleoplasm Nucleoplasm "CAB018701: AB_2164654" "unprognostic (1.99e-1)" "unprognostic (6.11e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.62e-1)" "unprognostic (8.33e-3)" "unprognostic (8.66e-4)" "unprognostic (1.47e-1)" "prognostic unfavourable (5.22e-4)" "unprognostic (6.68e-2)" "unprognostic (2.38e-2)" "unprognostic (3.27e-2)" "unprognostic (0.00e+0)" "unprognostic (2.96e-3)" "unprognostic (1.78e-1)" "unprognostic (9.61e-2)" "unprognostic (5.95e-2)" 1.8 1.1 0.6 12.9 0.6 6.0 0.6 0.6 1.2 1.2 5.2 0.6 0.6 3.3 2.0 1.3 4.6 0.8 1.4 0.9 0.6 1.8 0.7 0.6 1.9 7.5 0.9 0.6 0.6 0.6 0.0 0.6 1.4 1.0 2.5 1.8 0.9 0.8 1.2 0.6 1.6 3.7 2.1 0.6 7.0 2.7 3.3 0.6 14.3 0.6 5.1 6.0 1.8 1.9 0.7 0.3 0.0 0.0 0.0 3.2 0.4 5.1 6.0 14.7 5.9 2.6 3.1 5.4 5.1 2.7 5.1 4.0 9.5 8.6 6.2 2.1 2.5 14.3 15.1 4.3 1.9 9.9 5.5 7.2 16.9 6.8 1.3 2.9 5.9 1.7 0.0 2.2 1.8 5.2 4.7 12.5 4.8 4.5 3.0 12.0 12.0 4.2 6.4 4.9 8.7 2.8 2.9 6.1 3.9 3.9 4.3 2.3 4.8 3.1 3.5 3.1 16.1 4.9 9.3 10.1 9.3 5.9 2.9 12.7 4.4 0.0 0.0 0.0 1.5 0.0 0.5 0.7 0.1 1.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.3 3.2 0.4 0.6 0.6 0.6 1.2 0.6 1.8 0.9 0.6 1.0 0.6 PIGL ENSG00000108474 "Phosphatidylinositol glycan anchor biosynthesis class L" Q9Y2B2 17 16217191-16351797 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "GPI-anchor biosynthesis" Hydrolase "Deafness, Disease mutation, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012739 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" "Nucleoplasm, Cytosol" "HPA012739: AB_1855367" "unprognostic (3.07e-2)" "unprognostic (2.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" "unprognostic (7.70e-2)" "unprognostic (6.14e-2)" "unprognostic (9.39e-5)" "unprognostic (1.11e-2)" "unprognostic (1.15e-2)" "unprognostic (1.63e-2)" "unprognostic (6.37e-3)" "prognostic unfavourable (2.57e-4)" "prognostic unfavourable (1.47e-4)" "unprognostic (3.19e-2)" "unprognostic (2.13e-1)" "unprognostic (3.38e-1)" "unprognostic (2.75e-3)" 17.3 12.6 11.1 14.3 18.8 8.6 18.0 14.6 15.6 12.9 13.0 17.6 12.8 17.1 19.8 20.2 12.6 13.1 12.7 8.8 8.5 7.5 11.2 18.5 12.5 12.0 14.5 10.7 16.5 16.5 11.9 18.1 10.3 13.6 14.0 14.4 15.5 14.8 16.3 13.4 20.0 15.8 10.1 9.7 12.3 14.8 11.1 13.6 13.7 15.7 11.1 20.4 10.9 12.3 5.2 7.4 5.5 3.7 5.4 9.3 3.3 8.2 11.8 8.0 6.6 11.5 10.8 3.3 4.6 5.5 7.7 13.8 12.0 10.6 4.0 9.4 4.4 12.1 9.8 5.8 11.1 8.6 25.7 8.0 8.2 14.3 12.3 3.4 5.2 9.1 15.2 13.5 15.4 8.8 9.5 5.1 6.1 8.2 6.2 8.0 3.1 6.1 6.1 6.7 11.6 8.7 4.5 4.2 6.0 4.8 3.4 9.4 3.7 3.1 5.7 7.0 4.3 4.6 13.0 3.6 0.1 6.5 8.8 8.5 4.4 0.0 3.7 5.5 6.5 3.2 5.6 5.2 8.5 5.0 2.7 4.4 9.3 7.5 0.0 5.4 2.4 7.4 6.7 3.3 11.1 18.8 14.6 15.6 8.5 7.5 14.5 10.7 13.6 13.6 PIP4P1 "C14orf9, MGC26684, TMEM55B" ENSG00000165782 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1" Q86T03 14 20457719-20461612 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048528 Approved "HPA048528: " "unprognostic (1.84e-1)" "unprognostic (6.23e-2)" "unprognostic (1.81e-1)" "unprognostic (7.07e-2)" "unprognostic (2.04e-1)" "unprognostic (8.51e-2)" "unprognostic (1.71e-2)" "unprognostic (3.37e-3)" "unprognostic (4.94e-2)" "unprognostic (1.33e-1)" "unprognostic (7.78e-3)" "unprognostic (1.85e-1)" "prognostic favourable (1.01e-4)" "unprognostic (4.80e-2)" "unprognostic (1.47e-1)" "unprognostic (7.53e-2)" "unprognostic (1.96e-1)" 15.9 16.8 19.7 15.1 24.7 42.2 15.6 23.8 41.0 14.4 19.2 22.9 12.6 17.9 15.6 29.3 16.5 16.4 18.0 15.9 20.2 23.5 18.7 17.7 17.3 16.8 18.9 22.2 15.3 21.1 28.4 20.0 22.6 28.5 16.1 16.5 20.3 16.1 17.2 22.2 22.1 22.1 16.7 17.0 22.0 18.0 13.3 18.5 14.2 17.7 12.8 20.8 17.5 14.0 13.3 10.6 6.9 3.3 4.6 6.6 2.4 11.2 17.8 12.0 13.9 18.8 11.7 22.0 10.7 21.1 14.7 17.9 10.5 18.4 10.2 9.3 13.4 11.9 14.6 11.9 13.1 13.3 10.8 7.3 8.5 15.4 25.7 13.4 15.0 15.1 16.2 17.0 17.4 13.6 6.1 20.7 12.2 12.9 18.2 11.9 8.0 24.5 13.5 11.6 6.7 13.8 25.5 17.3 12.9 11.0 18.2 13.7 9.1 12.7 9.4 13.5 17.2 20.2 9.5 23.4 29.9 14.5 9.3 10.4 14.6 1.3 3.3 6.9 4.7 2.4 4.0 13.3 5.6 5.1 4.1 11.3 6.4 6.6 4.2 4.6 2.0 10.6 4.2 2.4 19.7 24.7 23.8 41.0 20.2 23.5 18.9 22.2 28.5 18.5 PIP4P2 "DKFZp762O076, TMEM55A" ENSG00000155099 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2" Q8N4L2 8 90993796-91041064 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "neutrophil: 36.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 36.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014591 Approved 57000 "HPA014591: AB_1858124" "unprognostic (6.09e-2)" "prognostic unfavourable (1.01e-4)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.54e-4)" "prognostic unfavourable (3.76e-5)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (7.58e-2)" "unprognostic (4.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.25e-2)" "prognostic unfavourable (8.01e-4)" "unprognostic (1.59e-1)" "unprognostic (9.05e-2)" "unprognostic (7.99e-2)" 15.8 18.6 18.7 9.1 19.5 35.2 11.7 21.4 31.7 14.2 16.5 11.1 7.3 4.4 15.0 7.1 8.5 8.6 15.5 26.0 18.2 23.5 13.7 5.7 8.1 11.8 22.8 20.0 16.1 4.8 14.6 13.4 12.2 25.5 12.3 7.2 17.4 10.1 18.6 16.7 8.0 6.6 18.6 25.4 11.2 9.6 9.7 21.1 7.1 9.4 6.9 7.7 13.3 10.5 1.5 5.3 36.2 5.6 1.2 2.4 2.9 2.6 1.6 9.4 5.9 15.3 18.1 1.9 11.4 13.5 5.8 8.6 1.0 4.4 5.1 1.5 10.9 0.6 2.2 3.7 7.6 4.7 4.6 8.1 1.7 0.8 13.8 1.9 7.3 10.0 2.4 7.3 5.4 5.5 4.0 17.0 20.1 1.8 5.4 4.8 4.9 5.9 2.2 3.8 6.1 8.1 1.6 1.0 5.3 0.7 3.6 13.9 0.1 3.3 8.3 10.4 4.3 6.0 4.8 6.8 4.1 3.1 18.0 3.4 13.9 0.3 5.6 5.3 0.8 2.6 1.3 1.5 1.8 0.9 5.3 1.1 2.4 1.0 36.2 1.2 1.0 3.1 1.5 2.9 18.7 19.5 21.4 31.7 18.2 23.5 22.8 20.0 25.5 21.1 PLA2G10 GXPLA2 ENSG00000069764 "Phospholipase A2 group X" O15496 16 14672545-14694669 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.4;stomach 1: 13.0" "Cell line enhanced" "Detected in some" "BEWO: 2.7;CAPAN-2: 4.5;SK-BR-3: 2.8;U-266/84: 2.3" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041893 Uncertain "Secreted in other tissues" "HPA041893: AB_10794495" "unprognostic (8.44e-3)" "unprognostic (2.37e-1)" "unprognostic (6.72e-2)" "prognostic favourable (5.74e-5)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (5.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.77e-2)" "unprognostic (2.72e-1)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.08e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-2)" "unprognostic (9.97e-3)" 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.3 9.4 2.4 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 13.0 2.1 0.0 0.0 2.8 0.0 0.9 0.5 2.0 0.5 0.1 0.4 0.1 0.1 1.0 0.1 0.2 0.0 0.1 2.7 0.2 0.0 0.0 0.0 0.7 4.5 0.4 0.5 0.0 2.2 0.0 0.0 0.0 0.2 0.1 0.4 0.4 0.0 0.1 0.8 0.9 0.0 0.1 0.0 0.1 0.0 0.2 0.7 0.0 2.1 0.4 0.3 0.4 0.1 0.8 0.3 0.2 0.0 0.3 0.6 0.5 1.1 2.8 0.4 0.5 0.4 0.9 0.0 0.3 0.1 0.0 0.8 2.3 0.7 0.7 0.1 0.1 0.1 0.5 0.5 0.3 0.4 0.3 0.1 0.2 0.4 0.5 0.9 0.3 0.3 2.0 0.1 0.3 0.3 0.1 0.1 PLA2G12A PLA2G12 ENSG00000123739 "Phospholipase A2 group XIIA" Q9BZM1 4 109709989-109730077 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035908, HPA035909" Approved "Secreted to blood" "HPA035908: , HPA035909: AB_10672074" "unprognostic (8.40e-2)" "unprognostic (3.87e-1)" "unprognostic (3.81e-3)" "unprognostic (3.09e-2)" "unprognostic (2.10e-1)" "unprognostic (1.35e-1)" "unprognostic (4.26e-2)" "unprognostic (1.77e-1)" "unprognostic (1.90e-1)" "unprognostic (2.71e-3)" "unprognostic (1.02e-1)" "unprognostic (8.42e-2)" "prognostic favourable (2.54e-9)" "unprognostic (3.10e-1)" "unprognostic (1.39e-1)" "unprognostic (9.16e-3)" "unprognostic (3.64e-2)" 9.8 9.9 13.1 4.4 16.2 5.6 12.9 14.5 14.3 9.6 12.2 13.4 7.3 11.9 8.9 8.2 12.6 9.2 9.2 21.0 13.0 11.4 15.3 20.6 7.8 4.9 16.8 11.7 11.9 38.8 22.8 19.0 10.4 12.7 16.4 12.0 10.7 12.1 8.3 21.1 9.8 16.3 8.1 20.3 5.5 10.0 5.7 12.4 4.9 19.0 9.2 6.2 7.5 7.7 4.9 8.7 3.6 4.6 4.9 10.2 13.8 9.6 3.6 2.8 4.2 9.0 9.1 5.6 9.0 7.1 5.0 5.3 8.9 17.1 14.0 6.8 6.5 5.4 8.7 11.6 7.8 5.2 13.5 4.9 10.5 5.4 9.0 10.7 3.5 9.2 13.5 5.1 12.7 5.1 27.2 6.5 8.6 17.1 8.7 4.8 5.0 14.1 5.3 8.5 11.0 9.4 14.4 18.3 6.0 7.9 20.8 6.7 12.5 2.3 6.0 7.4 6.1 7.6 6.1 11.0 19.8 10.3 8.3 6.3 9.1 3.6 4.6 2.7 7.2 2.9 6.6 4.2 9.0 6.9 8.7 4.9 10.2 9.2 2.2 4.9 4.4 7.6 8.7 13.8 13.1 16.2 14.5 14.3 13.0 11.4 16.8 11.7 12.7 12.4 PLA2G16 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754." ENSG00000176485 "Phospholipase A2 group XVI" P53816 11 63573195-63616883 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.6" "Cell line enhanced" "Detected in many" "A549: 32.3;ASC diff: 36.7;CAPAN-2: 59.1;HAP1: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 52.4" "Group enriched" "Detected in many" 5 "dendritic cells: 52.4;T-cells: 16.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058997 Uncertain Uncertain Mitochondria Mitochondria "HPA058997: " "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavourable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favourable (2.54e-5)" "unprognostic (2.35e-1)" 113.6 15.2 32.0 4.4 39.4 1.6 33.9 4.8 30.2 6.1 7.2 46.6 6.1 4.0 5.0 11.5 5.9 13.9 12.9 39.0 37.6 25.2 24.7 28.9 13.5 4.5 58.4 22.2 30.9 13.2 15.1 8.1 16.2 30.5 5.9 3.7 8.8 10.1 13.2 37.8 2.4 7.5 8.0 70.4 6.4 10.2 17.8 48.9 0.1 17.1 11.1 2.3 8.0 4.7 2.1 52.4 0.4 6.2 5.3 16.0 6.4 20.4 32.3 0.9 0.0 36.7 6.3 5.9 0.7 6.5 5.4 2.7 7.3 59.1 0.0 13.6 1.6 1.0 30.6 1.6 4.1 25.2 1.2 0.3 7.8 1.2 21.9 0.0 0.3 3.8 0.1 13.5 0.5 8.5 0.3 2.3 5.7 3.5 0.0 0.1 2.6 10.4 0.0 0.0 2.0 17.1 2.9 0.4 2.4 4.4 12.4 6.7 26.9 1.0 12.5 2.4 0.1 8.2 1.8 9.7 6.3 0.0 9.8 0.0 0.2 0.0 6.2 0.0 16.0 2.4 8.8 2.1 3.7 11.6 1.7 0.3 1.2 9.4 0.4 5.3 0.1 52.4 2.4 6.4 32.0 39.4 4.8 21.9 37.6 25.2 58.4 22.2 30.5 48.9 PLA2G1B "PLA2, PLA2A, PPLA2" ENSG00000170890 "Phospholipase A2 group IB" P04054 12 120322111-120327789 "Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 933 "pancreas: 2360.6" "Cell line enhanced" "Detected in some" "EFO-21: 2.2;Hep G2: 6.3;U-2 OS: 4.6" "Cancer enriched" "Detected in many" 185 "pancreatic cancer: 763.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.5" "Group enriched" "Detected in many" 19 "NK-cells: 1.3;T-cells: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047822, HPA060803" Enhanced "Secreted to digestive system" 3900000 "HPA047822: , HPA060803: " "unprognostic (1.28e-4)" "unprognostic (6.02e-2)" "unprognostic (1.84e-2)" "unprognostic (2.86e-2)" "unprognostic (2.74e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (3.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (2.80e-4)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (3.60e-1)" "unprognostic (8.61e-4)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 1.1 0.1 0.1 0.1 1.1 2360.6 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.3 2.5 0.9 0.2 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.5 0.0 0.3 1.3 0.3 1.6 0.0 0.0 0.2 0.0 0.6 0.0 1.0 0.2 4.6 0.6 0.6 0.0 1.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.3 0.0 0.0 2.5 0.9 0.0 1.3 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PLA2G2A "PLA2B, PLA2L" ENSG00000188257 "Phospholipase A2 group IIA" P14555 1 19975431-19980416 "Enzymes, FDA approved drug targets, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 377.9" "Group enriched" "Detected in some" 14 "Hep G2: 34.2;RT4: 31.4" "Cancer enhanced" "Detected in all" "prostate cancer: 875.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA015236 Enhanced "Secreted to blood" 1000000 290000 "HPA015236: AB_10601047" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (2.79e-2)" "unprognostic (7.85e-3)" "unprognostic (8.71e-2)" "unprognostic (9.27e-2)" "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "prognostic favourable (1.49e-4)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.77e-15)" "unprognostic (2.72e-2)" "unprognostic (9.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.51e-1)" 25.2 1.0 0.0 13.1 0.0 0.6 14.0 0.0 0.6 1.4 63.9 0.0 0.1 35.0 0.7 22.7 31.5 11.7 2.4 105.4 0.0 0.0 1.6 377.9 3.0 6.5 0.0 0.0 35.6 2.4 0.6 0.5 15.5 0.0 27.1 68.2 6.1 9.5 1.0 30.6 5.0 99.0 39.7 0.0 0.6 4.0 9.8 0.0 0.0 16.0 8.9 19.3 39.0 72.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 31.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G2D sPLA2S ENSG00000117215 "Phospholipase A2 group IID" Q9UNK4 1 20111939-20119566 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 39.9" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 13.4" "Cancer enriched" "Detected in many" 6 "testis cancer: 25.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.6;naive B-cell: 5.6;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 5 "B-cells: 6.6;dendritic cells: 3.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted - unknown location" "prognostic favourable (4.35e-4)" "prognostic favourable (8.15e-5)" "unprognostic (3.88e-3)" "prognostic favourable (9.74e-4)" "unprognostic (1.78e-1)" "unprognostic (2.56e-3)" "unprognostic (1.98e-1)" "unprognostic (1.60e-2)" "unprognostic (1.82e-5)" "unprognostic (7.51e-4)" "unprognostic (2.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.85e-1)" "unprognostic (8.08e-2)" "unprognostic (2.60e-1)" 0.4 0.3 0.3 38.8 0.3 0.0 0.4 0.3 0.3 0.3 0.9 0.0 0.0 0.3 0.3 0.2 0.4 0.5 0.4 0.3 0.3 0.3 0.4 0.4 1.0 39.9 0.3 0.0 0.3 0.3 0.0 0.3 0.2 0.0 0.4 1.2 0.1 5.0 0.3 0.3 0.3 7.7 0.0 0.3 18.1 0.6 0.3 0.0 6.6 0.7 0.5 33.0 2.5 0.3 6.6 3.4 1.0 0.2 0.3 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 13.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.0 0.3 0.1 2.1 0.1 0.2 0.1 0.1 0.0 1.0 0.2 0.2 0.1 0.1 0.1 6.6 0.1 0.1 0.1 5.6 0.1 0.1 0.4 0.3 0.1 3.4 0.0 0.2 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.0 0.0 0.0 PLA2G2E ENSG00000188784 "Phospholipase A2 group IIE" Q9NZK7 1 19920009-19923617 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "lymphoid tissue: 7.7;skin 1: 3.2" "Cell line enhanced" "Detected in some" "CACO-2: 2.2;CAPAN-2: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064085 Uncertain "Secreted - unknown location" "HPA064085: " "unprognostic (9.56e-2)" "unprognostic (3.71e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G2F ENSG00000158786 "Phospholipase A2 group IIF" Q9BZM2 1 20139326-20150386 "Enzymes, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Innate immunity, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 11.1;skin 1: 13.7;urinary bladder: 19.5" "Cell line enriched" "Detected in single" 67 "RT4: 54.8" "Cancer enriched" "Detected in some" 18 "urothelial cancer: 17.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "hippocampal formation: 3.3" "Not detected" "Not detected" "Intracellular and membrane" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-2)" "unprognostic (1.79e-2)" "unprognostic (5.11e-2)" "unprognostic (4.63e-2)" "unprognostic (4.83e-2)" "unprognostic (1.51e-1)" "unprognostic (1.61e-2)" "unprognostic (3.36e-5)" "unprognostic (7.06e-2)" "unprognostic (1.84e-1)" "unprognostic (4.69e-1)" "prognostic favourable (3.86e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.8 0.0 7.7 0.0 0.0 0.0 0.0 0.0 13.7 0.1 6.5 0.0 0.0 0.3 0.1 0.0 2.8 0.0 6.3 11.1 19.5 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134809-31140607 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 13.1;skin 1: 14.1;tongue: 17.4" "Group enriched" "Detected in some" 5 "AF22: 13.9;AN3-CA: 14.0;NTERA-2: 7.1;SCLC-21H: 10.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021016 Uncertain "Secreted to blood" "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favourable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" 0.1 0.0 0.1 0.1 0.2 0.0 2.0 0.4 0.9 5.3 0.1 0.1 1.9 0.5 0.3 0.1 13.1 0.0 0.1 0.1 0.6 0.0 0.3 0.1 4.2 0.1 0.1 0.4 0.1 0.1 1.7 0.1 0.1 3.1 0.4 0.0 0.8 1.8 0.5 0.3 14.1 0.1 0.1 0.1 0.1 0.9 0.3 0.1 0.4 0.8 17.4 3.5 0.1 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 14.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.9 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.9 0.6 0.0 0.1 0.4 3.1 0.1 PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828953-186988981 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 52.6;parathyroid gland: 63.5;seminal vesicle: 56.1" "Cell line enhanced" "Detected in many" "A549: 16.7;HeLa: 24.3;RPMI-8226: 30.2;U-2197: 28.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 7.1;eosinophil: 7.7;intermediate monocyte: 8.4;myeloid DC: 7.8;non-classical monocyte: 3.9;plasmacytoid DC: 3.2" "Group enriched" "Detected in many" 7 "dendritic cells: 7.8;granulocytes: 7.7;monocytes: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Cytosol 78000 Cytosol "CAB010050: AB_631312, HPA050062: , HPA054206: " "prognostic favourable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favourable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" 6.0 8.6 3.4 3.5 5.3 2.2 3.8 1.5 4.7 8.5 10.9 2.9 52.6 5.4 7.7 7.4 7.0 12.3 4.2 6.6 3.3 2.5 6.7 1.1 4.9 5.2 6.5 1.4 5.1 3.8 63.5 2.7 2.9 5.6 10.9 4.2 2.9 5.8 56.1 0.6 6.1 10.3 14.6 7.5 4.2 5.1 2.7 5.3 0.4 2.7 5.9 2.3 19.4 9.4 0.0 7.8 7.7 8.4 1.1 0.2 1.5 0.0 16.7 0.0 0.0 10.5 4.2 0.0 0.6 6.4 0.8 1.4 0.1 6.6 0.0 0.0 0.0 1.2 10.4 3.1 0.3 5.1 0.2 3.1 24.3 0.0 6.5 4.5 1.6 2.3 2.2 8.4 1.7 7.0 6.8 2.5 0.0 0.0 0.0 0.0 0.9 2.2 0.0 0.0 30.2 0.0 2.3 0.1 0.0 2.5 0.8 2.9 0.3 6.2 1.4 6.2 0.8 28.5 1.3 1.0 0.0 0.0 2.3 13.6 8.8 0.1 7.1 7.7 0.0 8.4 0.2 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.6 1.1 3.9 3.2 0.0 1.5 3.4 5.3 1.5 4.7 3.3 2.5 6.5 1.4 5.6 5.3 PLA2G4B "cPLA2-beta, HsT16992" ENSG00000243708 "Phospholipase A2 group IVB" P0C869 15 41837775-41848147 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 36.0;skin 1: 32.8;tongue: 56.0" "Cell line enhanced" "Detected in many" "RT4: 11.0;T-47d: 5.9" "Not detected" "Not detected" "Region enriched" "Detected in all" 4 "cerebellum: 10.8" "Cell type enhanced" "Detected in some" "NK-cell: 3.9" "Low lineage specificity" "Detected in many" "unprognostic (6.16e-2)" "unprognostic (6.48e-3)" "unprognostic (5.06e-3)" "unprognostic (1.27e-4)" "unprognostic (1.06e-1)" "unprognostic (2.56e-3)" "unprognostic (1.53e-1)" "unprognostic (2.27e-2)" "unprognostic (3.60e-2)" "unprognostic (1.90e-2)" "unprognostic (1.23e-2)" "unprognostic (5.14e-3)" "unprognostic (3.26e-5)" "unprognostic (4.36e-1)" "unprognostic (5.91e-2)" "unprognostic (1.22e-1)" "unprognostic (2.97e-2)" 1.8 1.2 1.8 1.8 2.2 3.4 3.6 10.8 2.1 6.1 1.8 1.8 1.8 1.9 2.7 2.3 19.3 2.0 1.9 1.8 1.8 2.5 2.5 2.6 2.2 3.3 1.8 1.8 4.2 3.5 1.4 3.2 1.8 1.8 4.8 1.1 1.8 7.0 2.7 1.8 32.8 2.4 1.8 1.8 3.0 1.8 1.8 1.8 2.2 4.8 56.0 36.0 2.0 5.9 3.0 0.5 0.2 0.8 3.9 1.5 0.1 1.3 0.7 0.0 0.0 0.1 0.0 3.7 0.4 1.2 1.3 0.1 0.3 0.7 0.3 0.1 0.7 4.4 1.5 0.5 0.3 0.0 2.5 1.1 1.4 3.4 1.7 0.2 1.4 0.9 4.9 0.2 1.3 0.6 1.7 0.2 0.4 2.1 1.0 4.1 1.0 1.2 0.0 1.2 0.9 1.0 11.0 0.2 1.1 0.0 2.0 1.0 5.9 1.8 0.0 0.0 1.0 1.0 0.1 3.4 0.0 0.9 0.3 5.0 0.0 0.0 0.8 0.0 1.5 0.5 0.9 0.1 0.4 0.8 0.5 3.0 0.9 0.8 0.2 3.9 0.2 0.5 1.2 0.1 1.8 2.2 10.8 2.1 1.8 2.5 1.8 1.8 1.8 1.8 PLA2G4C cPLA2-gamma ENSG00000105499 "Phospholipase A2 group IVC" Q9UP65 19 48047843-48110817 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.8;skeletal muscle: 45.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 8.0;HHSteC: 13.1;TIME: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 7.9" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA043083 Approved Approved Cytosol Cytosol "HPA043083: AB_10795714" "unprognostic (1.27e-1)" "unprognostic (3.88e-2)" "unprognostic (4.18e-2)" "unprognostic (2.82e-2)" "unprognostic (7.37e-2)" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (6.53e-2)" "unprognostic (8.30e-2)" "unprognostic (1.94e-1)" "unprognostic (5.11e-3)" "unprognostic (1.90e-1)" "unprognostic (4.66e-2)" "unprognostic (9.45e-2)" "unprognostic (2.28e-3)" "unprognostic (1.87e-1)" "unprognostic (9.01e-2)" 4.0 11.7 8.9 4.2 23.2 0.4 3.0 12.9 14.5 3.4 3.5 23.4 2.0 5.1 6.8 5.2 3.6 4.3 4.6 18.5 10.0 10.0 4.4 3.8 5.9 7.2 31.8 8.5 2.0 4.1 14.8 4.6 4.1 16.9 5.7 2.9 5.4 3.1 6.7 45.0 4.9 6.7 8.1 18.6 8.1 2.4 2.4 17.1 0.7 3.3 7.5 4.3 4.9 2.1 5.4 2.0 0.0 7.9 1.5 0.8 2.0 0.6 1.1 0.0 0.3 5.1 3.0 0.1 1.3 8.0 1.2 3.4 0.0 2.1 0.0 1.7 3.2 0.2 0.0 0.2 1.9 0.8 0.1 0.0 0.3 1.1 13.1 0.0 1.7 0.6 0.3 0.5 5.3 5.0 0.0 7.2 1.9 2.0 0.0 0.1 0.1 0.1 0.1 1.8 0.6 2.4 0.3 0.7 0.1 1.4 2.5 6.2 0.7 1.8 18.3 2.2 0.7 2.5 0.9 0.4 1.3 0.2 1.6 0.0 4.3 0.0 3.2 0.0 0.2 7.9 0.6 5.4 0.8 0.0 2.0 1.6 0.0 0.0 0.0 1.5 2.0 1.4 0.2 2.0 8.9 23.2 12.9 14.5 10.0 10.0 31.8 8.5 16.9 17.1 PLA2G4D cPLA2delta ENSG00000159337 "Phospholipase A2 group IVD" Q86XP0 15 42067009-42094554 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "cervix, uterine: 35.6;prostate: 22.4;skin 1: 13.9;tongue: 11.6;vagina: 17.1" "Cell line enriched" "Detected in single" 38 "RPMI-8226: 19.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (1.16e-1)" "unprognostic (1.10e-2)" "unprognostic (2.91e-2)" "unprognostic (9.16e-3)" "unprognostic (9.33e-3)" "unprognostic (4.35e-2)" "unprognostic (5.39e-2)" "unprognostic (2.37e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-2)" "unprognostic (2.75e-1)" "unprognostic (2.64e-7)" "unprognostic (2.54e-2)" "unprognostic (2.34e-1)" "unprognostic (3.47e-2)" "unprognostic (4.32e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 35.6 0.1 0.1 0.1 0.0 1.4 0.3 1.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 22.4 0.0 0.1 0.6 0.1 0.1 13.9 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.4 0.1 11.6 1.2 0.6 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981582-42051190 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 19.9" "Group enriched" "Detected in some" 7 "CACO-2: 3.4;HaCaT: 2.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041105 Enhanced "HPA041105: " "unprognostic (2.98e-1)" "unprognostic (5.52e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.22e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-7)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (4.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G4F PLA2G4F/Z ENSG00000168907 "Phospholipase A2 group IVF" Q68DD2 15 42139034-42156636 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 30.4;skin 1: 48.1" "Cell line enriched" "Detected in some" 4 "RT4: 13.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042713, HPA056752" Enhanced Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA042713: AB_10793982, HPA056752: " "unprognostic (1.99e-1)" "unprognostic (6.21e-3)" "unprognostic (1.59e-1)" "prognostic unfavourable (2.00e-4)" "unprognostic (1.06e-2)" "unprognostic (2.32e-3)" "unprognostic (1.48e-2)" "unprognostic (5.85e-2)" "unprognostic (2.25e-1)" "unprognostic (4.79e-2)" "unprognostic (6.65e-2)" "unprognostic (1.21e-2)" "unprognostic (9.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" "unprognostic (1.63e-1)" 0.1 0.1 0.0 2.5 0.3 0.3 1.8 0.0 0.1 4.5 11.0 0.0 4.7 4.2 0.4 9.7 10.4 0.2 3.1 1.0 0.0 0.0 10.8 0.2 30.4 0.1 0.0 0.0 0.1 0.1 0.7 4.1 0.3 0.0 3.3 2.5 0.0 5.3 2.8 8.6 48.1 12.3 1.1 0.1 0.2 1.6 0.1 0.0 6.2 1.6 14.9 3.4 2.2 6.3 0.6 0.3 0.2 0.1 0.0 0.3 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.7 0.5 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.0 3.2 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 13.2 0.7 0.1 0.0 1.4 0.0 1.4 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G5 ENSG00000127472 "Phospholipase A2 group V" P39877 1 20028179-20091190 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 48.3;retina: 58.3" "Cell line enhanced" "Detected in some" "EFO-21: 2.4;HaCaT: 1.0;hTEC/SVTERT24-B: 1.5;U-138 MG: 3.1;U-2197: 6.6" "Group enriched" "Detected in many" 5 "glioma: 13.0;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 23 "plasmacytoid DC: 2.3" "Lineage enriched" "Detected in single" 23 "dendritic cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053361 Approved "Secreted - unknown location" "HPA053361: " "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (5.68e-3)" "unprognostic (6.16e-2)" "unprognostic (2.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.70e-3)" "unprognostic (6.00e-5)" "unprognostic (2.87e-2)" "unprognostic (3.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.97e-3)" 2.6 0.5 2.8 2.0 6.7 0.2 1.9 1.9 5.2 0.3 10.5 2.1 2.5 1.2 0.5 2.1 5.7 1.9 3.0 48.3 2.6 2.4 0.2 1.8 3.2 1.0 6.1 2.0 17.3 1.2 0.2 0.1 8.3 6.8 6.9 3.2 58.3 1.0 10.3 0.4 0.4 1.0 19.3 1.0 0.8 2.3 3.3 1.3 0.0 0.7 0.0 1.7 7.3 2.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 3.1 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 2.8 6.7 1.9 5.2 2.6 2.4 6.1 2.0 6.8 1.3 PLA2G6 "iPLA2, iPLA2beta, NBIA2, PARK14, PNPLA9" ENSG00000184381 "Phospholipase A2 group VI" O60733 22 38111495-38205690 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" "Calmodulin-binding, Hydrolase" "Disease mutation, Dystonia, FDA approved drug targets, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 31.4;HMC-1: 20.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001171 Approved Approved "Centriolar satellite,Cytosol" "Centriolar satellite, Cytosol" "HPA001171: AB_1079145" "unprognostic (5.26e-2)" "prognostic favourable (7.29e-4)" "unprognostic (8.74e-2)" "unprognostic (6.27e-2)" "unprognostic (3.83e-1)" "unprognostic (3.70e-3)" "unprognostic (8.67e-3)" "unprognostic (9.55e-2)" "unprognostic (3.48e-1)" "unprognostic (1.91e-1)" "unprognostic (2.37e-3)" "unprognostic (4.95e-2)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (3.00e-1)" "unprognostic (1.48e-1)" "prognostic favourable (1.55e-4)" 16.2 17.7 15.6 8.5 20.5 13.1 15.6 15.9 26.3 14.8 7.9 36.9 18.5 9.8 16.3 20.5 8.7 21.6 25.3 6.3 19.7 7.2 18.1 8.6 9.0 12.4 19.3 16.7 21.3 12.8 24.2 12.7 6.8 19.5 17.6 6.3 12.9 20.2 17.4 7.4 18.1 8.7 7.8 14.9 12.1 9.5 30.0 23.2 16.3 45.7 4.1 11.3 12.1 11.2 1.8 5.4 4.1 0.9 8.8 5.7 1.9 0.7 2.8 3.0 7.7 10.0 4.9 8.1 0.9 0.9 0.8 1.1 3.1 1.8 5.8 6.6 2.3 3.6 3.4 1.9 1.0 8.9 13.1 31.4 3.8 3.5 2.8 3.5 20.1 16.1 4.3 2.8 4.4 1.0 5.1 10.6 1.5 4.6 6.5 2.1 2.5 1.8 4.8 1.1 4.5 2.9 6.9 5.7 2.4 1.3 3.1 7.1 3.2 2.5 1.2 2.6 4.4 1.1 0.5 17.4 3.1 3.1 3.7 4.0 1.5 4.1 0.9 0.4 3.8 0.3 1.9 1.8 3.1 5.7 1.5 1.5 1.4 3.9 3.3 8.8 0.6 5.4 3.7 1.9 15.6 20.5 15.9 26.3 19.7 7.2 19.3 16.7 19.5 23.2 PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Asthma, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 57.0;lymphoid tissue: 32.9" "Cell line enhanced" "Detected in some" "NTERA-2: 3.8;PC-3: 7.7;RT4: 3.5;U-2 OS: 3.7" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 24.2" "Group enriched" "Detected in many" 56 "dendritic cells: 7.9;monocytes: 24.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" 7380000 170000000 "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" 57.0 2.1 2.8 14.0 5.8 1.1 2.9 2.0 2.7 1.5 4.4 2.0 0.4 2.3 2.9 1.6 0.8 1.4 3.6 2.0 2.1 1.7 1.0 4.3 19.0 22.2 3.2 1.8 4.0 0.9 0.1 3.1 15.8 2.3 8.5 6.6 2.8 2.5 1.6 0.9 2.3 3.7 1.5 7.1 32.9 1.4 0.7 2.0 6.4 13.1 0.6 6.0 7.2 0.8 0.1 7.9 0.2 24.2 0.0 0.2 6.1 0.0 0.5 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 1.5 0.0 0.1 0.0 0.2 1.9 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.3 3.8 7.7 0.0 0.0 0.1 0.0 3.5 0.1 0.5 0.0 0.0 0.0 1.0 1.0 0.0 0.0 3.7 0.1 0.8 0.1 0.0 0.0 0.0 0.2 1.3 0.0 24.2 0.1 0.0 5.0 0.2 0.1 0.0 0.0 7.9 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 6.1 2.8 5.8 2.0 2.7 2.1 1.7 3.2 1.8 2.3 2.0 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42175233-42207724 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 132.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.8;HMC-1: 55.1;LHCN-M2: 55.6;U-2197: 58.0;WM-115: 115.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 2.1;T-reg: 2.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;T-cells: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" 9900000 12000 "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favourable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavourable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 19.3 14.9 5.2 12.9 6.8 0.4 13.3 2.2 6.2 24.5 17.1 9.1 19.0 11.2 35.5 28.1 18.1 19.1 18.5 7.3 6.0 5.9 67.6 2.8 15.9 1.9 8.2 3.6 18.4 5.8 132.2 5.1 15.5 9.4 27.4 12.2 39.4 6.1 12.7 5.8 2.0 31.7 23.0 7.0 1.0 14.6 12.2 3.8 0.6 11.2 14.7 7.4 47.9 13.7 0.3 0.1 1.6 0.0 0.0 2.3 0.3 0.5 0.2 4.2 1.0 7.7 10.5 0.1 18.0 32.0 7.7 6.6 0.2 85.8 0.0 0.6 2.3 1.4 0.0 4.0 15.9 7.8 1.4 0.1 0.1 0.1 37.9 0.0 55.1 10.5 0.0 18.8 0.7 14.4 0.5 0.1 55.6 0.0 0.0 0.0 5.6 7.6 0.0 15.6 0.0 2.5 0.0 0.0 0.9 0.0 0.1 24.5 0.1 0.0 27.5 1.5 5.7 58.0 1.8 0.0 0.1 0.0 1.2 0.0 115.3 1.6 0.0 0.0 0.3 0.0 1.0 0.3 2.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.3 0.3 5.2 6.8 2.2 6.2 6.0 5.9 8.2 3.6 9.4 3.8 PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917497 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 48.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 68.9;LHCN-M2: 66.5;RPTEC TERT1: 252.9;U-251 MG: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 2.4;neutrophil: 4.5;plasmacytoid DC: 4.5" "Group enriched" "Detected in many" 11 "dendritic cells: 4.5;granulocytes: 4.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008719 Approved "Secreted to blood" 647333 58000 "HPA008719: AB_1858635" "unprognostic (1.96e-2)" "unprognostic (2.99e-2)" "unprognostic (7.40e-2)" "prognostic favourable (3.38e-4)" "unprognostic (4.73e-2)" "prognostic unfavourable (2.70e-4)" "unprognostic (1.39e-2)" "prognostic unfavourable (4.04e-4)" "unprognostic (2.26e-1)" "unprognostic (6.58e-2)" "prognostic unfavourable (1.32e-4)" "unprognostic (1.61e-1)" "prognostic unfavourable (3.51e-4)" "unprognostic (2.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" 26.7 2.4 1.0 15.5 2.1 11.3 9.7 1.6 1.5 6.9 5.8 2.9 4.9 3.8 10.7 21.2 9.1 6.5 10.7 14.3 1.3 1.0 23.3 2.3 23.4 5.5 1.6 1.5 6.8 3.7 3.6 1.8 48.4 3.1 7.5 6.7 4.5 10.6 5.0 12.2 9.0 8.1 8.4 2.5 23.8 7.8 5.8 1.3 4.8 10.9 11.6 8.2 16.3 9.3 0.1 4.5 4.5 0.4 0.0 0.0 0.3 13.0 7.0 3.0 0.1 0.2 5.0 0.1 7.9 37.2 3.2 5.1 0.1 68.9 0.0 14.7 1.1 9.0 0.0 13.3 3.7 0.7 0.0 0.0 0.3 0.1 6.1 1.1 2.6 13.3 1.6 22.2 8.6 9.2 0.0 0.0 66.5 0.0 0.0 1.7 0.8 18.3 0.0 9.0 0.0 252.9 10.3 0.0 0.0 0.0 0.3 0.2 0.0 1.8 23.3 0.2 1.6 1.7 67.9 0.0 0.1 0.1 17.9 1.9 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 4.5 0.0 0.0 4.5 0.0 0.3 1.0 2.1 1.6 1.5 1.3 1.0 1.6 1.5 3.1 1.3 PLB1 "FLJ30866, PLB" ENSG00000163803 "Phospholipase B1" Q6P1J6 2 28457145-28643788 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 66.7" "Cell line enhanced" "Detected in some" "AF22: 4.7;BEWO: 7.2;CACO-2: 4.7;RT4: 5.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 14 "classical monocyte: 3.1;eosinophil: 3.3;intermediate monocyte: 4.9;myeloid DC: 6.4;neutrophil: 9.9;non-classical monocyte: 5.2" "Group enriched" "Detected in many" 40 "dendritic cells: 6.4;granulocytes: 9.9;monocytes: 5.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "unprognostic (2.18e-2)" "unprognostic (2.49e-1)" "unprognostic (6.58e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (4.91e-3)" "unprognostic (4.74e-2)" "unprognostic (4.48e-2)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" "unprognostic (2.17e-1)" "unprognostic (2.61e-9)" "unprognostic (2.48e-2)" "unprognostic (2.19e-2)" "unprognostic (4.99e-2)" "unprognostic (8.03e-2)" 0.9 3.3 0.7 1.0 2.1 2.9 1.0 0.6 0.7 0.9 0.8 0.6 0.6 0.2 0.8 1.7 1.3 0.7 0.9 1.4 0.6 0.9 0.8 0.6 0.7 0.6 0.8 0.6 0.6 0.6 0.0 0.7 1.3 0.7 1.0 1.1 0.7 0.6 0.9 0.9 5.2 66.7 1.7 0.8 2.8 0.5 1.2 0.6 0.6 1.2 0.9 0.6 0.9 0.6 0.0 6.4 9.9 5.2 0.0 0.1 1.1 0.8 0.1 4.7 0.1 1.0 0.7 7.2 0.2 1.9 0.5 0.4 4.7 0.5 0.5 0.5 0.7 1.0 0.0 3.8 0.4 0.3 0.1 0.4 0.7 0.8 1.6 0.8 0.3 0.8 2.2 0.7 1.2 1.2 0.0 0.1 1.3 0.0 0.0 0.6 0.2 1.0 0.0 0.8 0.0 2.1 5.3 2.1 0.4 0.2 0.3 0.4 0.0 2.5 0.5 0.5 1.4 0.2 0.2 1.0 0.2 0.0 1.7 3.6 0.1 0.0 3.1 3.3 0.0 4.9 0.0 0.0 0.1 0.0 6.4 0.0 0.0 0.0 9.9 0.0 5.2 0.3 0.1 1.1 0.7 2.1 0.6 0.7 0.6 0.9 0.8 0.6 0.7 0.6 PLCB1 "KIAA0581, PLC-I, PLC154" ENSG00000182621 "Phospholipase C beta 1" Q9NQ66 20 8077251-8968360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 56.7" "Cell line enhanced" "Detected in many" "CACO-2: 21.6;Hep G2: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004275, CAB005334, HPA034743, HPA057910" Enhanced Approved "Plasma membrane" 5400 "Plasma membrane" "CAB004275: AB_628118, CAB005334: AB_632196, HPA034743: , HPA057910: " "unprognostic (2.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.63e-2)" "unprognostic (9.77e-2)" "unprognostic (9.87e-2)" "unprognostic (2.37e-1)" "unprognostic (1.27e-4)" "unprognostic (1.13e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" "unprognostic (7.12e-3)" "unprognostic (6.57e-2)" "unprognostic (2.87e-3)" "unprognostic (3.20e-2)" "unprognostic (4.41e-2)" "unprognostic (1.71e-2)" "unprognostic (2.12e-1)" 5.6 7.0 13.8 4.4 27.7 3.4 5.9 7.5 31.1 6.5 9.9 2.1 20.6 5.5 8.0 10.3 4.5 7.4 6.6 8.6 15.7 9.1 10.0 3.1 4.0 1.6 9.3 14.5 3.2 10.8 56.7 4.6 14.2 5.5 10.4 3.6 1.3 19.7 22.2 9.8 2.3 4.5 12.3 4.0 2.9 5.5 2.6 8.0 4.1 3.1 1.9 1.1 8.6 6.3 0.5 0.8 2.8 3.3 2.4 5.2 0.4 0.0 0.6 2.3 0.1 4.3 8.1 3.1 9.7 6.4 2.5 1.5 21.6 2.4 1.0 4.1 1.8 0.0 1.7 0.0 1.9 0.0 2.1 0.4 1.6 32.5 1.1 0.5 0.3 0.5 0.4 3.4 0.0 5.1 3.3 12.6 0.0 2.9 0.4 1.5 7.3 3.5 6.9 0.0 5.7 1.9 8.0 8.3 3.6 0.0 2.0 0.4 9.6 3.1 0.9 8.3 3.7 0.6 6.0 9.5 11.0 16.3 4.2 5.9 14.3 0.8 3.3 2.8 3.6 0.7 5.2 0.2 1.0 1.3 0.4 0.5 0.5 1.1 2.1 2.4 0.4 0.8 0.2 0.4 13.8 27.7 7.5 30.8 15.7 9.1 9.3 14.5 5.5 8.0 PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 30.5;lymphoid tissue: 36.3" "Cell line enhanced" "Detected in some" "HEL: 30.8;HMC-1: 38.5;THP-1: 11.1;U-937: 21.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009443, HPA041298" Approved Approved Cytosol Cytosol "CAB009443: AB_632197, HPA041298: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favourable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavourable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" 6.3 3.6 8.1 17.6 11.6 30.5 2.9 1.1 7.5 2.9 3.3 16.2 1.7 4.0 2.8 3.2 2.4 4.6 6.5 3.3 6.9 5.1 3.3 4.2 12.5 17.2 12.7 2.4 1.6 2.0 1.3 2.9 4.6 9.3 3.2 5.5 4.1 5.2 2.9 1.3 1.5 10.2 4.8 17.9 36.3 3.6 1.4 10.9 12.2 2.8 1.8 17.6 6.9 2.5 1.0 4.5 8.5 4.3 1.8 3.1 2.0 0.1 0.0 0.2 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 7.7 0.6 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.8 0.0 0.0 0.0 6.5 38.5 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 1.8 3.5 0.4 0.1 5.4 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 11.1 4.0 0.0 3.7 0.0 0.0 0.0 0.0 1.4 0.0 21.1 0.0 2.7 4.2 8.5 3.1 4.3 2.0 0.7 1.6 1.6 4.5 1.0 1.6 1.8 6.9 1.8 4.2 1.6 2.9 2.0 8.1 11.6 1.1 7.5 6.9 5.1 12.7 2.4 9.3 10.9 PLCB3 ENSG00000149782 "Phospholipase C beta 3" Q01970 11 64251523-64269150 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "intestine: 77.5" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 4.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009257, HPA039279, HPA043907" Enhanced Enhanced Nucleoplasm 94000 Nucleoplasm "CAB009257: AB_654079, HPA039279: AB_2676425, HPA043907: AB_2678726" "unprognostic (1.30e-1)" "unprognostic (1.21e-2)" "unprognostic (2.86e-1)" "unprognostic (2.35e-1)" "unprognostic (9.35e-2)" "unprognostic (6.23e-3)" "prognostic unfavourable (1.39e-4)" "unprognostic (2.44e-2)" "unprognostic (6.61e-2)" "unprognostic (1.26e-1)" "unprognostic (8.07e-3)" "unprognostic (1.00e-2)" "prognostic unfavourable (4.31e-5)" "unprognostic (5.04e-3)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (3.88e-2)" 5.8 9.7 6.1 7.0 5.4 3.7 10.9 6.3 5.8 8.6 40.6 3.1 8.8 59.3 9.1 5.9 16.8 7.7 11.8 4.8 5.4 2.6 5.5 3.2 9.1 4.8 3.5 2.2 11.0 4.0 7.6 2.9 11.1 4.8 6.4 7.0 5.0 6.5 6.3 3.8 10.7 77.5 7.0 4.5 7.2 8.0 4.6 5.4 4.2 5.0 8.2 9.3 6.3 8.8 0.3 4.4 0.9 1.4 0.3 0.8 0.4 17.6 9.9 9.8 14.6 10.3 8.0 9.8 14.1 10.7 12.1 7.4 8.7 13.5 1.2 8.5 17.7 30.5 11.0 13.2 4.2 8.5 6.1 13.8 20.5 6.5 7.1 3.3 9.1 6.7 8.8 13.1 9.8 17.6 6.8 1.5 15.3 21.3 4.2 7.0 15.9 10.9 9.2 22.1 5.2 7.4 18.7 2.6 10.8 20.9 26.3 10.0 13.8 6.4 30.5 11.2 13.4 25.6 9.1 1.9 0.9 1.4 18.5 7.9 10.3 0.0 1.4 0.2 0.7 1.4 0.8 0.1 0.8 0.7 1.3 0.3 0.4 0.4 0.9 0.3 1.4 4.4 0.2 0.4 6.1 5.4 6.3 5.8 5.4 2.6 3.5 2.2 4.8 5.4 PLCB4 ENSG00000101333 "Phospholipase C beta 4" Q15147 20 9068763-9481242 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.9;retina: 40.2;salivary gland: 39.8" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 38.0;hTERT-HME1: 18.6;LHCN-M2: 30.6;RPTEC TERT1: 39.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.5" "Group enriched" "Detected in all" 4 "cerebellum: 44.9;pons and medulla: 11.9" "Cell type enriched" "Detected in single" 20 "plasmacytoid DC: 6.6" "Lineage enriched" "Detected in single" 20 "dendritic cells: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007951 Approved Approved Nucleoplasm,Microtubules Microtubules Nucleoplasm "HPA007951: " "unprognostic (3.88e-2)" "unprognostic (3.62e-1)" "unprognostic (1.19e-2)" "prognostic favourable (2.11e-4)" "unprognostic (1.44e-2)" "unprognostic (9.72e-3)" "unprognostic (3.32e-3)" "unprognostic (2.57e-2)" "unprognostic (7.75e-2)" "unprognostic (4.23e-2)" "unprognostic (5.21e-3)" "unprognostic (1.35e-1)" "unprognostic (4.64e-3)" "unprognostic (7.12e-2)" "unprognostic (1.37e-1)" "unprognostic (2.22e-1)" "unprognostic (4.45e-2)" 5.5 5.0 2.1 4.5 4.6 0.2 5.6 44.9 5.2 6.0 13.1 2.7 2.4 1.6 12.3 16.2 6.9 10.9 6.2 12.4 2.3 6.6 2.3 0.9 4.4 1.0 4.0 3.3 2.9 1.3 0.5 15.1 4.4 11.9 6.9 12.6 40.2 39.8 7.1 2.5 4.3 3.1 12.3 3.1 1.1 9.7 2.1 2.4 4.3 21.9 4.4 2.0 7.1 8.8 0.0 6.6 0.0 0.0 0.3 0.0 0.0 0.0 6.1 3.0 0.0 0.0 0.1 0.0 13.3 3.8 4.0 2.5 1.1 0.9 0.0 0.2 38.0 0.0 0.9 2.9 6.0 0.0 1.8 1.6 2.2 0.0 0.5 0.0 0.0 0.9 1.2 5.1 18.6 0.0 1.5 0.1 30.6 1.9 0.0 0.0 3.2 3.8 0.0 0.0 0.2 39.1 2.8 10.2 7.0 0.0 9.2 5.6 7.8 0.0 0.1 4.3 0.3 0.4 5.2 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.0 0.0 2.1 4.6 44.9 5.2 2.3 6.6 4.0 3.3 11.9 2.4 PLCD1 ENSG00000187091 "Phospholipase C delta 1" P51178 3 38007496-38029762 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 15.7;ASC TERT1: 14.0;fHDF/TERT166: 15.4;hTCEpi: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009913, HPA020107, HPA021677" Approved Approved Microtubules Microtubules "CAB009913: AB_2163388, HPA020107: AB_1855318, HPA021677: AB_1855319" "unprognostic (1.75e-3)" "unprognostic (1.01e-2)" "unprognostic (4.29e-2)" "unprognostic (1.45e-2)" "unprognostic (3.44e-1)" "unprognostic (9.67e-3)" "unprognostic (1.55e-1)" "unprognostic (7.25e-3)" "unprognostic (3.95e-1)" "unprognostic (1.45e-1)" "unprognostic (2.80e-1)" "unprognostic (2.24e-1)" "prognostic favourable (9.25e-11)" "unprognostic (1.50e-1)" "unprognostic (7.71e-2)" "unprognostic (2.93e-1)" "unprognostic (7.88e-2)" 10.9 11.3 11.2 5.6 12.1 5.1 8.0 6.0 11.2 11.6 19.3 15.2 7.3 6.6 9.1 7.6 21.9 8.6 8.5 8.0 13.0 6.9 7.8 5.8 9.4 9.3 10.5 11.4 12.8 6.2 4.7 7.3 6.9 15.9 10.6 12.7 8.3 10.9 12.6 4.5 17.0 6.5 12.3 15.5 6.3 6.5 37.3 8.7 7.7 6.6 21.2 12.2 14.6 23.1 1.0 2.6 8.6 2.4 3.7 13.2 5.4 0.6 1.7 5.6 1.5 15.7 14.0 1.7 1.7 6.7 2.6 4.0 0.6 1.3 0.4 0.9 15.4 9.0 2.9 1.7 0.8 2.5 0.7 0.2 0.9 2.8 9.2 0.0 1.0 11.3 19.2 7.8 1.0 4.9 9.4 0.8 5.7 0.7 1.3 0.6 1.5 1.7 0.5 0.8 2.1 3.1 3.0 0.0 1.6 0.5 7.5 1.8 1.6 0.7 2.8 1.6 4.0 4.1 0.0 3.4 1.3 0.3 4.0 0.0 0.8 8.6 1.9 0.1 10.2 2.4 11.6 1.0 13.2 9.8 2.6 0.5 7.8 6.1 6.9 3.7 1.4 1.5 11.8 5.4 11.2 12.1 6.0 10.7 13.0 6.9 10.5 11.4 15.9 8.7 PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108967-45133354 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 63.6" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Approved "Plasma membrane" "Plasma membrane" "HPA025711: AB_1855320, HPA053665: " "unprognostic (3.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" "unprognostic (4.14e-3)" "unprognostic (8.13e-3)" "prognostic unfavourable (2.89e-6)" "unprognostic (2.96e-1)" "unprognostic (9.53e-2)" "unprognostic (1.34e-3)" "unprognostic (6.21e-2)" "unprognostic (3.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "prognostic favourable (4.28e-4)" "unprognostic (3.34e-3)" 5.7 12.0 10.1 4.8 16.5 2.4 6.6 12.2 12.9 5.0 24.9 14.0 2.8 2.9 6.3 6.4 8.9 5.8 9.4 13.1 11.6 6.6 3.6 1.2 4.5 1.7 13.9 11.4 9.9 2.7 1.5 3.0 5.7 19.5 5.8 13.7 10.3 4.7 5.7 63.6 9.9 2.8 12.9 15.0 2.0 17.9 5.4 14.6 0.0 2.3 20.1 2.8 17.5 10.5 1.3 0.9 2.9 1.5 1.3 0.9 0.5 9.0 22.8 1.7 3.3 2.5 5.4 11.5 5.0 11.2 4.6 4.4 5.6 16.7 0.3 18.1 11.7 20.9 2.6 21.5 1.8 4.5 8.6 0.3 24.0 7.1 12.9 0.5 1.3 5.8 8.7 4.3 5.7 2.8 1.9 0.7 4.9 14.3 1.4 2.1 2.0 22.5 3.2 3.8 0.6 14.7 18.2 0.4 3.0 5.4 9.1 4.9 19.3 1.0 5.7 2.9 16.0 3.8 5.8 0.8 1.0 0.7 4.7 0.6 2.3 2.3 1.5 2.4 0.9 1.5 0.6 1.0 0.7 0.6 0.5 1.3 0.9 0.8 2.9 1.3 0.3 0.9 0.6 0.5 10.1 16.5 12.2 11.5 11.6 6.6 13.9 11.4 19.5 14.6 PLCD4 ENSG00000115556 "Phospholipase C delta 4" Q9BRC7 2 218607765-218637184 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "retina: 23.0;skeletal muscle: 62.5;smooth muscle: 33.1" "Cell line enhanced" "Detected in many" "SH-SY5Y: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009914, HPA038139, HPA038140" Enhanced Approved "Nuclear membrane,Plasma membrane,Cytosol" Cytosol "Nuclear membrane, Plasma membrane" "CAB009914: AB_2252306, HPA038139: AB_2675855, HPA038140: AB_2675856" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.76e-2)" "unprognostic (5.65e-5)" "unprognostic (7.77e-2)" "unprognostic (1.45e-2)" "unprognostic (7.06e-3)" "unprognostic (2.86e-2)" "unprognostic (3.15e-1)" "unprognostic (8.87e-3)" "unprognostic (7.54e-5)" "unprognostic (3.28e-2)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (6.32e-2)" "unprognostic (8.46e-3)" "unprognostic (3.09e-1)" 1.1 2.5 1.5 1.0 1.6 0.5 1.0 0.9 2.4 0.6 6.4 0.3 3.8 0.9 0.8 1.1 3.7 0.6 0.9 0.9 1.0 1.5 3.9 0.5 0.7 0.7 1.6 1.0 0.7 0.4 1.4 4.7 0.6 2.6 6.4 1.5 23.0 1.4 0.6 62.5 0.8 1.4 33.1 1.1 0.5 3.5 3.9 0.5 0.0 1.4 6.8 0.5 9.6 5.3 0.9 1.2 0.3 0.4 0.9 0.9 1.0 0.6 1.5 2.1 0.4 0.2 1.4 1.2 1.2 2.6 0.4 1.4 2.4 0.3 1.4 1.8 0.4 1.0 0.0 1.5 0.3 0.5 1.8 1.2 3.5 1.9 0.2 1.2 0.6 3.0 0.1 1.9 0.5 2.7 1.0 1.1 2.2 1.8 0.4 1.2 0.7 3.4 0.9 0.8 0.5 4.3 3.0 2.3 21.1 1.0 0.8 0.3 2.5 0.5 6.0 1.5 1.2 0.7 0.7 0.5 0.8 0.9 4.6 0.3 1.6 0.0 0.4 0.0 0.5 0.0 0.1 0.0 0.3 0.9 0.3 0.9 0.7 0.8 0.3 0.9 0.0 1.2 0.7 1.0 1.5 1.6 0.9 2.4 1.0 1.5 1.6 1.0 2.6 0.5 PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 94030812-94332823 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 44.6" "Cell line enhanced" "Detected in many" "RT4: 18.7;U-2 OS: 11.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol Cytosol "HPA015597: AB_1855321, HPA015598: AB_1855322" "unprognostic (4.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.59e-3)" "unprognostic (3.01e-1)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (4.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-3)" "unprognostic (3.56e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" "unprognostic (4.30e-2)" 3.2 2.4 4.1 9.1 5.5 0.0 2.2 1.8 7.9 9.2 13.8 3.1 1.6 5.0 11.4 4.6 4.5 4.2 3.8 12.8 4.1 2.6 6.3 0.7 7.2 0.4 2.4 6.8 3.2 12.8 0.1 5.2 3.1 6.4 3.3 12.6 44.6 2.1 7.7 4.3 0.7 4.6 5.8 2.4 5.8 8.7 1.7 2.3 0.0 15.1 7.3 1.1 7.9 5.4 3.2 1.2 0.8 0.9 1.1 2.3 0.5 6.0 8.3 1.8 1.0 1.0 5.9 2.3 3.7 1.0 0.8 1.2 5.4 1.5 0.7 1.9 3.0 2.6 4.2 1.0 1.3 0.4 2.1 0.4 4.6 0.5 0.1 0.8 0.3 2.4 0.0 2.2 0.0 0.0 0.4 0.3 7.2 0.2 0.7 0.8 0.6 8.7 0.1 5.7 0.2 0.2 18.7 0.8 1.5 4.4 6.0 0.5 5.1 0.5 0.6 3.9 11.2 2.3 4.9 0.5 0.2 0.3 3.1 1.0 3.5 0.4 0.5 0.1 1.5 0.9 1.3 2.6 1.6 1.1 0.6 3.2 2.3 1.8 0.8 1.1 0.8 1.2 0.6 0.5 4.1 5.5 1.8 7.9 4.1 2.6 2.4 6.8 6.4 2.3 PLCG1 "NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1" ENSG00000124181 "Phospholipase C gamma 1" P19174 20 41136960-41196801 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 5.9;MAIT T-cell: 8.0;memory CD4 T-cell: 5.2;memory CD8 T-cell: 4.9;naive CD4 T-cell: 5.7;naive CD8 T-cell: 5.4;NK-cell: 4.0;T-reg: 4.4" "Group enriched" "Detected in many" 8 "NK-cells: 4.0;T-cells: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004277, HPA036681, HPA036682" Approved Enhanced Cytosol Cytosol "CAB004277: AB_628119, HPA036681: , HPA036682: " "unprognostic (2.77e-1)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "unprognostic (4.31e-2)" "unprognostic (5.82e-2)" "unprognostic (2.09e-2)" "unprognostic (4.45e-3)" "unprognostic (1.25e-2)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "prognostic favourable (4.72e-4)" "unprognostic (3.32e-1)" "unprognostic (2.73e-3)" "unprognostic (1.82e-1)" "unprognostic (2.65e-1)" "unprognostic (9.27e-2)" "unprognostic (2.79e-2)" 20.2 15.1 25.1 20.9 22.1 8.3 34.9 52.6 26.8 19.9 13.9 23.4 12.5 16.5 27.6 13.9 13.5 17.0 18.7 20.9 25.4 13.6 15.3 6.8 19.3 30.7 18.5 20.5 28.7 9.1 16.9 14.2 22.2 18.7 18.4 13.2 20.0 13.2 20.6 13.4 22.3 17.1 22.2 15.4 20.1 12.4 19.9 23.9 48.1 28.5 11.9 21.9 17.1 21.1 0.7 0.0 0.0 0.0 4.0 8.0 3.3 5.3 6.8 32.9 24.1 13.2 9.3 10.5 8.8 11.4 17.8 15.2 16.4 1.8 12.0 10.9 9.6 10.0 14.3 15.8 10.4 3.4 7.6 0.8 11.4 19.3 10.0 4.7 3.3 11.8 8.9 13.1 10.3 19.9 8.9 7.9 16.1 40.1 28.9 3.7 12.2 12.6 23.1 24.0 5.9 9.8 9.9 11.7 22.4 15.8 7.4 15.9 8.6 5.5 21.4 42.7 13.9 13.6 10.7 8.9 3.9 10.0 10.2 5.1 17.7 0.0 0.0 0.0 5.9 0.0 8.0 0.3 5.2 4.9 0.0 0.7 5.7 5.4 0.0 4.0 0.0 0.0 4.4 3.3 25.1 22.1 52.6 26.8 25.4 13.6 18.5 20.5 18.7 23.9 PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81739097-81962693 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 55.8" "Cell line enhanced" "Detected in some" "Daudi: 39.6;HMC-1: 19.0;U-698: 87.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Vesicles 21000 Vesicles "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favourable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favourable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" 8.4 3.8 3.3 55.8 4.9 14.1 10.7 1.0 2.4 5.6 10.3 5.3 3.1 8.7 11.2 12.2 6.0 4.7 10.1 4.4 3.3 2.8 20.6 8.8 10.7 35.5 5.2 1.8 2.0 3.6 1.0 1.8 4.1 4.5 4.3 3.6 4.6 8.8 2.8 2.0 4.1 17.6 4.6 8.6 33.6 4.2 2.3 4.2 6.3 5.3 2.6 44.6 7.5 7.7 18.8 3.9 26.8 12.2 14.0 1.1 2.3 0.3 0.7 0.1 0.6 0.0 0.0 0.9 0.0 0.0 0.5 0.2 0.2 1.7 39.6 6.8 0.0 0.9 0.8 0.1 0.3 0.3 0.4 4.7 0.0 0.0 0.2 4.7 19.0 0.0 0.4 0.3 0.2 0.9 0.5 3.3 0.0 1.2 0.5 11.9 0.7 0.2 16.1 0.0 5.0 0.1 0.8 0.3 0.0 1.1 0.3 0.3 0.7 14.6 0.2 0.0 0.7 0.1 0.1 7.9 12.9 87.9 0.0 6.5 0.3 2.8 4.4 26.8 0.7 5.7 0.3 18.8 0.2 1.1 3.9 17.3 0.3 0.8 24.8 14.0 12.2 2.6 0.1 2.3 3.3 4.9 1.0 2.4 3.3 2.8 5.2 1.8 4.5 4.2 PLCH1 "DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3" ENSG00000114805 "Phospholipase C eta 1" Q4KWH8 3 155375580-155745067 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.7;testis: 15.8" "Cell line enhanced" "Detected in some" "A549: 8.2;AF22: 26.6;NTERA-2: 14.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.2" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036176, HPA057978" Uncertain Enhanced Vesicles Vesicles "HPA036176: AB_10671837, HPA057978: " "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (2.17e-2)" "unprognostic (1.55e-2)" "unprognostic (3.50e-4)" "unprognostic (6.41e-2)" "unprognostic (2.94e-5)" "unprognostic (5.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.24e-3)" "unprognostic (4.84e-2)" "unprognostic (1.76e-2)" "prognostic favourable (3.03e-5)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-2)" 0.3 0.3 3.9 0.7 14.1 0.5 3.9 7.4 14.7 2.1 3.9 5.7 4.1 3.9 1.4 12.9 0.5 12.4 2.4 2.5 4.5 3.6 2.1 0.4 6.1 0.3 3.4 7.3 0.5 2.5 0.8 3.2 0.8 6.5 0.8 3.9 5.6 2.3 3.4 0.6 0.5 3.9 0.5 1.9 0.3 5.8 15.8 2.9 0.0 8.9 0.0 0.4 1.3 0.4 0.1 0.3 0.7 0.0 0.0 1.2 0.9 0.0 8.2 26.6 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.5 6.6 0.0 0.5 0.0 0.0 4.7 0.0 0.0 0.0 2.4 6.6 0.0 0.9 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.8 1.5 6.1 14.1 1.1 0.6 0.0 0.0 1.6 0.1 2.5 0.6 0.0 6.4 0.0 2.8 0.0 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.9 3.9 14.1 7.4 14.7 4.5 3.6 3.4 7.3 6.5 2.9 PLCH2 "KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1" ENSG00000149527 "Phospholipase C eta 2" O75038 1 2425980-2505530 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0;retina: 28.6;skin 1: 36.6" "Group enriched" "Detected in some" 4 "HBEC3-KT: 49.5;hTCEpi: 23.3;hTERT-HME1: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 9 "NK-cells: 2.9;T-cells: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072705 Enhanced "HPA072705: " "unprognostic (2.06e-3)" "unprognostic (1.30e-2)" "unprognostic (1.09e-3)" "unprognostic (3.84e-3)" "unprognostic (1.99e-1)" "unprognostic (1.59e-2)" "unprognostic (7.39e-2)" "unprognostic (7.70e-2)" "unprognostic (7.58e-2)" "unprognostic (9.28e-2)" "unprognostic (2.26e-1)" "unprognostic (5.95e-2)" "unprognostic (6.61e-3)" "unprognostic (8.43e-2)" "unprognostic (1.07e-1)" "unprognostic (8.64e-2)" "unprognostic (5.80e-2)" 0.5 1.2 6.4 2.9 9.1 1.4 3.1 32.0 25.1 3.2 0.9 1.6 0.5 1.6 0.3 1.7 9.7 2.5 2.4 0.3 20.2 2.7 0.8 0.8 1.2 4.0 2.6 8.4 0.2 1.7 0.1 3.0 0.4 2.6 6.7 0.7 28.6 8.6 4.9 0.2 36.6 2.0 0.2 6.4 4.0 1.7 0.8 2.0 0.2 1.2 0.2 4.9 8.3 6.4 0.3 0.1 0.0 0.0 2.9 2.4 0.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 6.9 0.0 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 13.9 0.0 0.0 1.2 0.1 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 2.7 5.6 1.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.9 0.3 1.5 1.4 0.0 0.3 1.1 0.7 0.0 2.9 0.0 0.1 2.1 0.9 6.4 9.1 32.0 25.1 20.2 2.7 2.6 8.4 2.6 2.0 PLCZ1 "NYD-SP27, PLCzeta" ENSG00000139151 "Phospholipase C zeta 1" Q86YW0 12 18683169-18738057 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fertilization, Lipid degradation, Lipid metabolism" "Developmental protein, Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 29.5" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.7;hTERT-HME1: 1.4;NTERA-2: 2.1;U-2 OS: 1.2;U-251 MG: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" "unprognostic (1.87e-2)" "unprognostic (1.39e-2)" "unprognostic (1.25e-2)" "unprognostic (1.59e-1)" "unprognostic (1.40e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.3 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 1.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.1 0.7 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600405-171810950 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 52.1" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 29.9;SK-MEL-30: 16.7;TIME: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 10.2" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004527, HPA042396" Enhanced "CAB004527: AB_677324, HPA042396: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (4.76e-6)" 7.0 26.6 5.3 6.1 20.4 4.5 6.3 1.4 10.8 8.6 19.7 31.4 1.8 27.7 6.9 4.9 25.0 4.9 52.1 14.7 7.7 4.7 7.5 20.2 4.4 5.2 25.3 7.2 17.1 13.9 0.9 2.7 6.6 18.8 3.5 9.4 8.5 13.2 4.2 2.0 17.6 29.5 3.4 16.8 9.9 5.3 3.5 21.8 0.9 4.1 10.7 8.5 4.3 11.5 0.1 0.9 10.2 2.6 3.0 4.1 0.8 2.3 3.7 1.9 0.7 5.9 6.7 4.1 1.2 5.2 1.8 2.3 0.5 3.3 0.0 9.3 0.5 7.8 0.3 1.0 3.0 1.9 1.6 2.2 5.9 13.0 2.7 3.8 10.4 2.6 5.7 2.2 1.0 29.9 1.4 0.0 0.4 0.6 0.0 3.2 0.4 2.7 0.1 0.8 0.0 4.7 0.9 0.0 0.0 4.1 2.5 16.7 4.6 5.0 26.0 0.8 3.2 2.1 1.3 5.0 4.0 0.0 3.6 4.5 1.0 10.2 2.6 3.2 0.5 1.6 4.1 0.0 0.4 1.0 0.9 0.1 0.0 0.1 1.5 3.0 0.5 0.0 1.2 0.8 5.3 20.4 1.4 10.8 7.7 4.7 25.3 7.2 18.8 21.8 PLD2 ENSG00000129219 "Phospholipase D2" O14939 17 4807096-4823434 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013397 Approved "HPA013397: AB_1855328" "unprognostic (1.87e-1)" "unprognostic (3.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (2.90e-2)" "unprognostic (3.85e-3)" "unprognostic (3.64e-1)" "unprognostic (6.15e-3)" "unprognostic (2.58e-3)" "unprognostic (1.25e-1)" "unprognostic (8.10e-3)" "unprognostic (1.08e-1)" "unprognostic (2.95e-1)" "unprognostic (1.91e-1)" "unprognostic (1.85e-1)" "unprognostic (5.48e-2)" 9.9 6.4 9.0 8.2 10.4 2.0 11.0 14.6 10.8 14.9 7.6 18.1 13.4 6.1 11.2 11.7 36.2 13.0 12.3 7.2 10.5 7.8 7.2 6.9 11.7 7.5 10.0 7.0 14.9 12.6 11.4 6.5 14.6 12.2 11.0 8.1 9.8 13.7 26.7 4.3 27.8 6.1 11.8 8.9 7.8 7.0 3.5 13.2 7.3 7.3 20.0 16.8 10.6 20.6 2.6 5.3 4.1 7.4 1.1 3.1 2.9 7.4 11.9 10.7 11.2 9.2 12.3 12.0 4.9 10.3 8.6 6.9 12.5 8.9 3.3 5.7 12.5 17.3 8.2 10.8 8.0 4.1 4.1 1.1 8.8 7.7 6.7 0.0 8.2 18.1 16.4 7.7 7.0 19.8 1.2 3.1 6.6 5.7 0.4 1.4 5.6 5.2 3.6 6.8 0.8 7.8 12.8 3.5 6.3 9.1 10.8 6.7 7.7 1.8 15.4 5.7 5.8 12.7 7.5 2.8 1.3 0.7 8.7 1.5 3.3 4.1 6.9 1.6 2.0 7.4 1.5 2.6 2.0 1.5 5.3 1.5 0.6 0.7 0.5 1.1 7.2 2.3 3.1 2.9 9.0 10.4 14.6 10.8 10.5 7.8 10.0 7.0 12.2 13.2 PLD3 HU-K4 ENSG00000105223 "Phospholipase D family member 3" Q8IV08 19 40348456-40380439 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response" "Exonuclease, Hydrolase, Nuclease" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "basophil: 149.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 149.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012800, CAB020812" Approved Supported "Endoplasmic reticulum,Cytosol" 490000 "Endoplasmic reticulum, Cytosol" "CAB020812: , HPA012800: AB_1855330" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.64e-3)" "unprognostic (2.56e-3)" "unprognostic (2.06e-3)" "unprognostic (2.68e-1)" "unprognostic (4.52e-2)" "unprognostic (3.89e-2)" "unprognostic (1.09e-1)" "unprognostic (4.60e-2)" "prognostic favourable (6.44e-4)" "unprognostic (4.34e-2)" "prognostic favourable (2.21e-4)" "unprognostic (3.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (6.42e-2)" 45.7 57.5 44.6 23.1 79.0 12.8 21.9 35.5 126.1 31.2 23.5 25.4 17.1 22.6 26.3 35.0 18.3 30.0 30.8 33.0 46.4 73.4 22.1 25.6 49.7 25.2 44.7 53.9 44.8 42.5 32.9 122.1 38.9 62.2 29.6 16.1 31.6 35.3 37.2 27.4 24.2 23.5 25.6 28.6 48.9 23.0 17.0 19.3 11.9 20.6 11.2 12.9 27.3 20.7 3.6 23.0 149.2 24.6 9.7 7.8 16.8 13.9 43.2 28.0 44.0 77.9 37.1 21.3 34.7 35.4 25.2 28.9 8.2 15.8 6.1 36.4 30.1 6.5 6.7 13.6 11.0 22.6 24.6 6.5 14.8 10.3 53.2 2.7 75.0 70.6 28.5 19.2 13.2 21.1 23.0 24.6 18.1 18.3 4.7 13.0 18.2 8.9 6.0 21.3 24.9 12.9 10.5 20.1 33.4 16.6 10.3 18.5 14.2 47.0 37.2 21.3 10.2 18.0 7.7 25.6 27.3 6.3 34.2 10.9 13.1 149.2 24.6 35.3 7.8 12.8 6.4 3.6 6.2 6.9 23.0 3.1 6.5 6.5 2.5 9.7 5.7 3.3 6.1 16.8 44.6 79.0 35.5 126.1 46.4 73.4 44.7 53.9 62.2 19.3 PLD4 C14orf175 ENSG00000166428 "Phospholipase D family member 4" Q96BZ4 14 104924816-104937790 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "blood: 229.9" "Group enriched" "Detected in some" 5 "HMC-1: 34.0;RPMI-8226: 24.4;THP-1: 61.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "plasmacytoid DC: 229.9" "Lineage enriched" "Detected in many" 5 "dendritic cells: 229.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051512 Uncertain 2000000 "HPA051512: " "unprognostic (4.50e-3)" "unprognostic (1.78e-4)" "unprognostic (7.12e-2)" "unprognostic (5.30e-3)" "unprognostic (5.54e-2)" "unprognostic (2.91e-3)" "unprognostic (2.56e-1)" "unprognostic (4.76e-3)" "unprognostic (1.45e-3)" "unprognostic (1.19e-3)" "unprognostic (3.45e-3)" "unprognostic (3.89e-1)" "unprognostic (6.90e-3)" "unprognostic (8.94e-2)" "unprognostic (2.83e-1)" "unprognostic (1.28e-2)" "unprognostic (2.41e-1)" 0.7 1.6 8.9 6.7 8.8 15.0 1.9 5.7 10.0 1.5 1.3 23.1 0.1 5.6 1.5 0.5 1.1 2.8 3.5 0.8 8.7 8.4 1.2 0.9 2.6 14.4 14.5 3.4 0.9 1.6 1.0 2.8 1.2 9.0 2.1 0.8 1.5 4.6 2.3 0.5 0.9 5.5 0.9 19.0 11.6 3.5 0.8 9.2 2.7 1.0 0.0 11.2 3.9 0.9 14.7 229.9 43.4 17.7 1.7 0.1 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.0 8.6 0.0 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.9 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 2.8 43.4 0.0 11.9 0.1 14.7 0.0 0.0 35.1 12.3 0.1 0.0 0.6 1.7 17.7 229.9 0.0 4.4 8.9 8.8 5.7 9.6 8.7 8.4 14.5 3.4 9.0 9.2 PLG ENSG00000122194 Plasminogen P00747 6 160702238-160753315 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 269.9" "Cell line enhanced" "Detected in some" "HL-60: 3.5;RH-30: 3.9;U-698: 2.0;U-937: 1.6" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000668, CAB016678, HPA021602, HPA048823" Supported "Secreted to blood" 140000000000 41000000000 "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: " "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favourable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 269.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.3 0.2 0.8 0.0 0.4 3.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 1.0 0.0 2.0 0.0 1.6 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55535050 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 91.2;fHDF/TERT166: 27.7;HMC-1: 47.8;HSkMC: 35.0" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" "Plasma membrane" "CAB033331: AB_2168044, HPA047815: " "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favourable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavourable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" 56.3 26.7 12.5 14.8 14.6 0.6 57.9 10.6 18.5 34.5 30.9 26.1 18.0 17.3 36.8 26.0 18.4 20.4 61.0 33.7 13.4 10.8 34.5 42.0 15.9 17.3 20.8 10.1 16.5 17.6 16.9 10.1 22.4 21.4 82.0 24.7 29.8 9.8 24.0 18.4 16.6 25.4 39.6 28.2 10.2 21.7 18.1 14.5 4.4 32.7 9.6 10.0 43.1 18.1 5.4 13.6 3.3 0.7 2.7 9.5 1.6 1.9 4.8 1.4 2.8 91.2 10.6 2.0 4.3 12.1 2.4 5.6 3.3 3.6 2.0 4.1 27.7 1.2 4.9 2.4 2.7 1.3 3.9 0.2 2.1 4.1 14.4 0.5 47.8 35.0 5.1 3.5 2.2 3.9 0.0 5.5 4.7 1.2 1.3 1.0 3.2 3.9 0.4 2.4 0.1 9.1 15.5 1.7 1.2 4.3 0.8 2.6 3.1 0.3 4.8 0.8 1.4 3.6 3.1 3.4 1.4 2.3 3.2 0.2 3.9 0.0 0.4 3.3 1.5 0.4 1.6 5.4 5.2 3.2 1.9 3.4 9.5 7.5 0.3 2.7 0.7 13.6 2.2 1.6 12.5 14.6 10.6 18.5 13.4 10.8 20.8 10.1 21.4 14.5 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291504 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 38.3;CAPAN-2: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 4.4;MAIT T-cell: 9.4" "Lineage enriched" "Detected in single" 52 "T-cells: 9.4" "Low region specificity" "Detected in many" HPA055540 Uncertain Approved Mitochondria Mitochondria "HPA055540: " "prognostic unfavourable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favourable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 1.4 4.7 8.3 5.3 20.9 0.2 17.5 2.0 11.1 30.4 18.2 28.1 13.4 27.5 7.7 4.1 9.1 38.1 31.2 1.5 13.6 7.1 4.7 1.1 3.7 0.8 37.1 6.5 2.4 19.8 0.6 4.1 1.8 16.6 10.7 15.3 6.7 45.8 19.0 0.3 19.0 21.9 3.3 26.0 1.4 22.2 2.2 25.8 0.7 2.2 5.9 5.0 12.1 5.7 0.0 0.1 0.1 0.0 0.0 9.4 0.3 22.5 38.3 0.5 0.0 0.0 0.1 0.0 2.2 0.0 7.1 5.5 11.0 41.6 0.0 24.5 3.3 12.5 0.0 4.9 3.2 0.2 0.7 0.0 15.4 0.0 8.5 0.0 1.5 1.5 2.1 3.6 4.9 1.2 0.1 0.0 0.0 25.6 0.1 0.0 17.0 0.0 0.0 0.0 0.6 17.9 3.6 4.8 11.5 6.3 10.5 16.5 13.8 0.7 1.2 15.6 10.3 0.1 16.6 0.2 26.2 18.5 4.4 0.0 12.8 0.0 0.0 0.0 4.4 0.0 9.4 0.0 2.0 2.2 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 8.3 20.9 2.0 11.1 13.6 7.1 37.1 6.5 16.6 25.8 PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494747-56645301 "Enzymes, Plasma proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 102.8;ASC TERT1: 51.4;HSkMC: 63.5;U-2197: 93.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 5.4;naive B-cell: 4.5" "Lineage enriched" "Detected in single" 7 "B-cells: 5.4" "HPA028892, HPA072751" Uncertain Supported "Golgi apparatus" "Golgi apparatus" "HPA028892: AB_10602149, HPA072751: " "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favourable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" 46.4 17.2 29.0 10.8 30.7 4.2 39.1 13.5 27.5 102.7 15.5 33.8 22.1 8.1 32.7 36.9 20.8 36.7 24.0 23.3 39.9 13.5 30.2 57.7 24.3 6.7 19.2 30.1 27.9 12.2 30.7 7.2 70.9 20.0 37.7 14.4 34.7 22.4 58.7 16.6 24.4 12.5 32.9 16.5 7.9 18.7 23.4 29.7 5.2 107.1 19.4 6.7 35.8 44.0 5.4 0.0 0.8 0.3 0.0 0.0 0.2 0.4 1.5 2.0 0.2 102.8 51.4 4.9 5.4 5.5 5.0 2.5 4.3 0.8 0.7 0.6 8.1 0.8 0.2 0.1 1.0 0.0 1.3 0.1 0.6 6.0 2.5 0.0 0.0 63.5 0.4 4.8 4.0 4.7 0.3 0.0 5.4 0.4 0.0 0.0 6.1 5.9 0.0 0.0 0.2 0.8 4.5 0.0 4.0 1.7 2.2 0.5 0.7 0.0 2.9 25.2 2.1 93.3 0.2 0.0 0.0 0.0 4.4 0.2 1.7 0.0 0.3 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 4.5 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.2 29.0 30.7 13.5 27.5 39.9 13.5 19.2 30.1 20.0 29.7 PLPP4 "DPPL2, PPAPDC1, PPAPDC1A" ENSG00000203805 "Phospholipid phosphatase 4" Q5VZY2 10 120456954-120589855 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.5;kidney: 12.6" "Cell line enhanced" "Detected in some" "BJ: 15.1;fHDF/TERT166: 10.7;TIME: 12.0;U-138 MG: 9.6;U-251 MG: 46.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 22 "eosinophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045188 Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA045188: " "unprognostic (8.19e-2)" "unprognostic (2.94e-2)" "unprognostic (8.86e-2)" "unprognostic (1.90e-3)" "unprognostic (3.45e-1)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (2.26e-3)" "unprognostic (1.55e-1)" "unprognostic (8.62e-3)" "unprognostic (2.70e-3)" "unprognostic (1.89e-1)" "unprognostic (2.40e-3)" "unprognostic (3.49e-2)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-3)" 0.6 1.7 11.4 1.2 13.6 4.9 3.1 11.6 18.2 3.4 1.2 12.1 1.0 0.7 1.7 2.7 0.9 1.2 11.3 0.7 15.9 17.4 12.6 2.8 0.5 0.6 15.5 6.0 0.6 0.6 0.4 0.5 0.6 26.5 3.0 0.8 0.0 2.0 6.1 0.4 1.7 0.8 1.5 19.1 0.5 1.2 11.1 12.5 0.0 1.5 0.0 0.5 0.8 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 1.1 2.3 1.4 0.1 1.3 0.0 0.0 10.7 0.1 0.9 0.2 1.2 1.4 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 1.1 0.0 8.7 0.9 2.1 0.9 0.0 0.0 0.0 0.9 2.7 0.0 0.0 0.0 4.4 0.0 0.8 0.2 0.7 0.0 0.7 1.9 0.0 12.0 9.6 5.3 0.5 46.4 0.0 0.0 0.0 8.9 0.0 2.5 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 13.6 11.6 10.0 15.9 17.4 15.5 6.0 26.5 12.5 PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Predicted membrane proteins" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 77.8" "Cell line enhanced" "Detected in many" "RPMI-8226: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "memory B-cell: 37.2;naive B-cell: 65.4" "Lineage enriched" "Detected in all" 5 "B-cells: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055777 Approved Vesicles Vesicles "HPA055777: " "unprognostic (4.54e-2)" "unprognostic (2.51e-3)" "unprognostic (3.66e-2)" "prognostic favourable (1.48e-5)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (5.58e-2)" "prognostic favourable (8.72e-5)" "unprognostic (9.79e-2)" "prognostic favourable (2.42e-5)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "prognostic unfavourable (8.33e-10)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (1.57e-2)" 5.5 9.3 6.9 11.9 7.9 4.8 8.8 7.5 6.7 11.2 11.5 3.9 33.9 14.4 5.7 30.9 6.6 10.2 21.0 4.6 6.1 6.1 9.6 20.3 7.5 12.0 4.5 5.1 8.4 77.8 4.2 29.9 8.3 6.7 27.9 12.8 16.2 52.0 36.5 2.3 4.7 18.4 5.2 3.5 12.8 16.1 4.6 4.4 3.8 11.9 5.0 14.8 8.0 6.7 65.4 5.3 13.3 3.6 4.3 5.0 3.7 5.4 10.9 6.5 13.3 12.8 12.5 9.0 15.6 19.7 8.0 10.5 5.0 8.4 0.4 13.3 16.1 6.1 5.4 11.4 6.9 3.4 3.5 9.6 4.6 14.6 21.8 2.8 11.7 9.8 11.9 11.1 14.6 12.9 0.4 25.2 9.7 11.3 6.3 4.7 9.9 3.7 6.9 4.8 50.8 20.0 7.1 5.2 7.9 6.4 9.9 9.1 21.3 5.4 7.7 5.7 5.0 9.5 4.1 15.7 10.2 1.6 15.6 7.4 9.7 13.3 2.7 4.5 3.0 2.7 5.0 37.2 3.9 3.8 2.5 65.4 2.0 1.9 1.6 4.3 3.6 5.3 3.4 3.7 6.9 7.9 7.5 6.7 6.1 6.1 4.5 5.1 6.7 4.4 PLPPR2 "LPPR2, PRG-4" ENSG00000105520 "Phospholipid phosphatase related 2" Q96GM1 19 11355386-11365698 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "neutrophil: 32.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048973 Uncertain Approved Nucleoplasm Nucleoplasm "HPA048973: " "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "prognostic unfavourable (6.45e-4)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (7.10e-2)" "unprognostic (1.37e-1)" "unprognostic (9.60e-2)" "unprognostic (1.72e-1)" "prognostic favourable (6.82e-4)" "unprognostic (2.23e-1)" "prognostic unfavourable (7.46e-11)" "unprognostic (1.99e-2)" "unprognostic (1.46e-1)" "unprognostic (4.37e-2)" "unprognostic (1.17e-1)" 12.0 17.1 32.5 10.5 39.9 14.1 6.6 17.7 51.2 14.0 11.1 10.8 5.1 6.0 12.7 8.4 8.4 9.7 13.7 10.4 37.0 22.3 5.5 18.0 10.0 5.4 11.8 17.9 15.2 12.4 11.7 22.7 11.5 12.3 18.5 5.1 11.8 13.1 15.1 23.1 16.2 5.7 16.8 10.5 10.6 9.3 7.6 9.4 0.5 7.7 4.4 3.3 9.8 8.1 0.0 2.9 32.3 7.2 0.0 0.3 2.3 8.7 5.4 3.0 12.5 12.7 12.2 0.8 15.6 14.6 9.7 9.9 1.0 1.6 1.7 9.3 19.9 1.6 1.7 4.7 5.2 4.6 3.2 0.5 3.8 1.0 6.6 0.5 17.8 10.9 8.5 8.3 1.6 6.5 8.4 14.0 8.1 12.9 0.2 2.4 3.3 30.4 0.2 0.4 4.8 4.5 4.1 3.2 10.8 6.5 5.6 3.3 8.1 11.2 7.5 22.0 4.7 37.1 8.2 8.7 5.3 0.6 21.3 8.0 8.6 0.8 7.2 3.7 0.3 6.7 0.0 0.0 0.1 0.0 2.9 0.0 0.1 0.0 32.3 0.0 4.4 0.1 0.3 2.3 32.5 39.9 17.7 51.2 37.0 22.3 11.8 17.9 12.3 9.4 PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821977 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 18.2;brain: 30.0;fallopian tube: 12.6" "Group enriched" "Detected in some" 6 "NB-4: 23.5;THP-1: 49.8" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 8 "eosinophil: 1.6" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: , HPA057034: " "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.33e-2)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.32e-1)" "unprognostic (4.51e-4)" "unprognostic (8.06e-3)" "unprognostic (1.07e-1)" "unprognostic (1.72e-12)" "unprognostic (1.21e-2)" "unprognostic (6.82e-2)" "unprognostic (8.50e-2)" "unprognostic (2.91e-1)" 0.7 0.7 20.5 1.2 30.0 18.2 2.1 0.1 21.3 0.9 0.7 0.7 0.0 0.7 1.3 0.7 0.7 12.6 1.1 0.7 14.4 13.1 0.7 0.7 2.6 0.9 3.9 14.9 1.0 0.7 0.7 0.1 0.8 4.7 0.9 0.7 0.1 0.7 0.8 0.9 0.8 1.0 0.7 1.1 0.9 0.9 3.0 3.1 0.0 0.7 0.0 0.7 0.8 0.0 0.1 0.0 1.6 0.0 0.0 0.1 0.0 0.1 0.6 4.8 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.4 0.0 0.1 0.9 0.0 0.0 0.0 2.0 0.0 0.6 0.0 0.2 1.6 0.1 0.6 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.4 0.0 23.5 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 6.2 0.1 0.0 0.0 2.1 49.8 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 3.8 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 30.0 0.1 21.3 14.4 13.1 3.9 14.9 4.7 3.1 PLPPR4 "KIAA0455, LPPR4, PHP1, PRG-1" ENSG00000117600 "Phospholipid phosphatase related 4" Q7Z2D5 1 99263953-99309590 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 55.3" "Cell line enhanced" "Detected in some" "BJ hTERT+: 19.8;BJ hTERT+ SV40 Large T+ RasG12V: 7.7;fHDF/TERT166: 6.7;SH-SY5Y: 14.9;U-138 MG: 7.5;U-87 MG: 12.6" "Cancer enhanced" "Detected in many" "glioma: 7.2" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 22 "non-classical monocyte: 2.1" "Lineage enriched" "Detected in single" 22 "monocytes: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (4.32e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-2)" "unprognostic (1.67e-2)" "unprognostic (2.95e-2)" "unprognostic (1.00e-2)" "unprognostic (1.17e-2)" "unprognostic (9.09e-2)" "unprognostic (9.70e-3)" "unprognostic (3.36e-2)" "unprognostic (2.21e-1)" "unprognostic (7.25e-12)" "unprognostic (1.67e-5)" "unprognostic (3.47e-1)" "unprognostic (1.34e-2)" "unprognostic (1.16e-3)" 3.0 1.7 25.1 1.2 25.8 0.8 1.8 2.0 55.3 4.6 1.5 2.6 0.0 1.2 1.7 1.7 3.2 1.3 6.0 1.4 39.2 10.8 1.4 0.8 3.5 1.5 5.2 16.7 0.8 1.5 1.7 9.0 1.9 6.1 1.1 1.9 0.6 1.4 1.3 1.2 4.6 1.5 2.1 2.2 1.3 1.1 5.2 2.7 0.0 1.5 0.4 1.7 7.0 1.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 3.8 19.8 4.4 7.7 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.2 14.9 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.1 0.0 0.1 0.0 0.0 0.0 12.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 25.1 25.8 2.0 33.8 39.2 10.8 5.2 16.7 6.1 2.7 PMPCA "Alpha-MPP, INPP5E, KIAA0123" ENSG00000165688 "Peptidase, mitochondrial processing alpha subunit" Q10713 9 136410570-136423761 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Disease mutation, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021648, HPA063735" Supported Enhanced Mitochondria 6500 Mitochondria "HPA021648: AB_1855491, HPA063735: AB_2685108" "unprognostic (9.80e-2)" "unprognostic (1.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.69e-2)" "unprognostic (4.01e-2)" "unprognostic (8.19e-2)" "unprognostic (6.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.97e-1)" "unprognostic (3.32e-2)" "prognostic favourable (8.00e-5)" "unprognostic (9.47e-3)" "prognostic favourable (2.14e-6)" "unprognostic (4.27e-3)" "unprognostic (1.57e-2)" "unprognostic (2.40e-1)" "unprognostic (3.54e-2)" 15.2 27.3 19.8 14.6 23.8 20.1 13.2 20.3 24.3 12.3 15.1 13.0 10.4 18.6 14.2 14.1 16.5 13.6 14.9 37.0 15.6 14.8 17.0 48.3 12.3 18.4 15.2 21.9 15.5 18.2 14.7 19.5 15.6 16.8 15.2 11.9 12.8 20.3 17.1 56.7 17.5 17.0 13.8 14.1 18.9 16.3 23.2 12.5 14.0 15.0 19.8 15.3 13.1 13.4 25.5 30.1 17.0 25.1 32.1 30.8 28.2 14.3 26.9 12.9 26.0 9.8 14.3 19.8 15.0 12.1 21.0 15.3 30.7 17.2 20.1 15.8 15.2 33.6 23.8 22.0 9.3 28.9 28.8 16.2 34.7 37.1 17.3 21.0 14.1 21.0 15.2 16.3 8.4 17.7 41.0 13.3 13.0 39.8 19.8 27.1 26.3 25.5 24.7 18.3 44.5 14.4 10.3 26.5 17.4 20.2 28.8 17.5 39.2 28.7 14.6 15.0 16.1 12.3 19.0 8.2 10.9 21.7 19.7 18.4 13.4 15.4 25.1 17.0 27.2 24.4 26.4 25.5 25.7 29.3 30.1 23.7 30.8 26.9 5.9 32.1 23.2 15.3 24.3 28.2 19.8 23.8 20.3 24.3 15.6 14.8 15.2 21.9 16.8 12.5 PMPCB "MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing beta subunit" O75439 7 103297422-103329511 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria 57000 Mitochondria "HPA040674: AB_10961998, HPA074168: " "prognostic favourable (2.79e-4)" "unprognostic (3.11e-1)" "unprognostic (7.18e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-2)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "unprognostic (7.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.42e-3)" "prognostic favourable (2.95e-8)" "unprognostic (2.59e-2)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" 29.1 41.8 31.8 23.0 34.3 41.5 31.6 41.1 38.4 29.0 26.9 21.6 28.2 35.1 32.0 25.9 27.9 26.9 23.5 41.4 27.7 20.1 45.9 47.2 21.9 31.3 32.6 35.0 36.8 40.6 41.1 33.9 24.8 34.2 31.6 31.5 20.8 30.6 31.0 31.5 31.6 31.0 25.7 27.8 27.9 33.6 31.3 35.9 37.2 33.2 24.2 30.0 30.7 27.9 19.5 18.4 9.7 16.1 12.9 21.9 15.7 12.1 17.6 20.8 27.9 12.6 25.6 15.7 11.3 19.5 22.9 27.3 18.8 14.0 31.3 18.2 19.3 15.8 24.9 18.2 21.9 10.9 29.7 10.8 30.2 25.0 15.4 14.8 12.8 23.4 17.0 17.9 17.3 12.1 20.9 31.8 20.9 28.3 24.6 35.0 25.4 22.1 17.2 14.5 31.8 21.5 21.8 26.1 31.9 15.3 45.2 22.3 18.5 19.9 10.0 20.3 24.3 36.0 21.0 24.4 31.2 24.0 15.0 24.0 15.9 9.7 14.1 9.3 14.7 16.1 16.1 19.5 17.1 14.7 18.4 14.3 21.5 17.4 4.4 12.9 13.6 9.4 21.9 15.7 31.8 34.3 41.1 38.4 27.7 20.1 32.6 35.0 34.2 35.9 PNKP PNK ENSG00000039650 "Polynucleotide kinase 3'-phosphatase" Q96T60 19 49859882-49878351 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease mutation, Epilepsy, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006782 Supported Supported Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA006782: AB_1855496" "prognostic favourable (9.18e-4)" "unprognostic (1.87e-1)" "unprognostic (4.31e-2)" "unprognostic (4.23e-1)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.24e-1)" "unprognostic (3.36e-1)" "unprognostic (1.58e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "unprognostic (4.55e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.24e-2)" "unprognostic (3.68e-3)" 13.1 32.4 11.2 22.0 11.8 24.3 15.0 18.0 13.8 14.0 17.4 17.0 26.4 15.6 16.7 25.3 13.6 18.1 18.2 16.8 12.3 9.5 20.1 16.8 15.9 21.0 13.9 14.2 17.1 22.5 19.7 26.8 17.1 12.9 18.7 15.0 19.6 20.3 22.4 12.8 15.3 15.7 13.2 10.1 30.7 17.9 17.2 13.9 22.3 23.0 17.0 20.6 14.6 12.4 7.9 7.5 19.3 12.7 2.7 7.7 3.8 12.8 8.7 8.8 13.8 8.4 6.5 14.3 20.8 10.6 9.6 8.4 6.9 16.9 8.3 6.6 6.3 10.5 3.1 11.7 5.7 10.7 13.3 14.1 16.4 6.0 6.3 13.3 19.0 6.1 6.2 8.7 5.7 12.6 6.9 16.8 12.5 8.2 13.5 10.7 8.2 17.7 11.5 8.1 16.8 9.9 27.5 10.4 16.8 9.1 27.4 4.6 4.7 8.3 17.8 18.8 11.5 4.5 17.1 18.6 7.5 6.7 17.0 6.0 14.9 1.4 8.8 12.2 7.7 8.5 6.4 6.5 6.6 5.8 7.5 7.9 4.9 4.4 19.3 2.7 12.7 4.3 6.8 3.8 11.2 11.8 18.0 13.8 12.3 9.5 13.9 14.2 12.9 13.9 PNLDC1 "dJ195P10.2, FLJ40240" ENSG00000146453 "PARN like, ribonuclease domain containing 1" Q8NA58 6 159800249-159820704 "Enzymes, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 26.7" "Cell line enhanced" "Detected in some" "AN3-CA: 1.8;HAP1: 2.3;hTCEpi: 3.8;RPMI-8226: 2.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basal ganglia: 5.7;cerebral cortex: 3.9" "Cell type enhanced" "Detected in some" "intermediate monocyte: 1.8;plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA052026 Uncertain "HPA052026: " "unprognostic (1.58e-1)" "unprognostic (3.88e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-3)" "unprognostic (8.47e-3)" "unprognostic (3.55e-2)" "unprognostic (2.04e-1)" "unprognostic (4.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.37e-2)" "unprognostic (4.19e-1)" "unprognostic (9.98e-2)" "unprognostic (2.69e-9)" "unprognostic (1.14e-2)" "unprognostic (2.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-1)" 0.6 0.5 0.6 0.5 5.7 0.4 1.4 0.2 3.9 0.3 0.3 0.3 0.0 0.2 0.3 1.3 0.2 3.6 0.3 0.2 0.7 0.2 0.8 0.8 0.5 0.4 0.4 0.7 0.8 2.3 0.3 0.3 0.3 0.3 0.4 0.3 0.0 1.2 0.4 0.5 1.4 0.3 0.3 0.4 0.5 0.3 26.7 0.3 0.5 0.4 0.3 0.7 0.2 0.0 0.1 1.7 0.0 1.8 0.4 1.0 0.4 0.0 0.4 0.2 1.8 1.0 0.0 1.1 0.0 0.0 0.1 0.0 1.3 0.0 0.1 0.2 0.3 0.1 2.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.0 3.8 0.0 0.1 0.0 0.1 0.8 0.2 0.1 0.8 0.1 0.9 0.8 0.1 0.0 2.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.2 0.3 0.0 0.3 0.7 0.1 0.0 0.6 0.1 0.0 0.2 0.0 0.1 1.8 0.0 0.0 0.2 0.0 0.7 0.1 1.0 0.1 0.0 0.4 0.0 1.7 0.5 0.4 0.6 5.7 0.2 3.9 0.7 0.2 0.4 0.7 0.3 0.3 PNLIP PL ENSG00000175535 "Pancreatic lipase" P16233 10 116545931-116567855 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1895 "pancreas: 3207.8" "Cell line enhanced" "Detected in some" "EFO-21: 3.0;HDLM-2: 2.7;U-2 OS: 4.5;U-251 MG: 1.0;U-266/84: 1.5" "Cancer enriched" "Detected in some" 4854 "pancreatic cancer: 2731.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 0.4" "HPA062430, HPA062494" Enhanced "Secreted to digestive system" 13000000 "HPA062430: AB_2684761, HPA062494: AB_2684782" "unprognostic (2.05e-2)" "unprognostic (4.46e-2)" 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.6 3207.8 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 1.0 0.0 1.5 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 PNLIPRP3 ENSG00000203837 "Pancreatic lipase related protein 3" Q17RR3 10 116427867-116477957 "Enzymes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 8.5;breast: 15.9;esophagus: 12.0;skin 1: 15.5" "Cell line enriched" "Detected in some" 18 "hTCEpi: 84.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046202, HPA052009" Uncertain "Secreted - unknown location" "HPA046202: AB_10959739, HPA052009: " "unprognostic (2.62e-4)" "unprognostic (1.60e-1)" "unprognostic (6.97e-2)" 8.5 0.1 0.0 0.0 0.2 0.0 15.9 0.0 0.0 1.6 0.2 0.0 0.0 0.1 0.0 0.4 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 15.5 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.3 0.0 8.1 1.9 0.7 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 84.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818902-825573 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 158.1;breast: 155.2" "Cell line enhanced" "Detected in all" "ASC diff: 64.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" "Lipid droplets" Nucleoplasm "HPA055173: , HPA062602: , HPA075175: " "unprognostic (2.11e-2)" "unprognostic (3.37e-2)" "unprognostic (5.87e-3)" "unprognostic (2.51e-2)" "unprognostic (8.97e-3)" "unprognostic (1.68e-2)" "unprognostic (6.39e-2)" "unprognostic (3.28e-2)" "unprognostic (3.00e-1)" "unprognostic (5.61e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (5.46e-1)" "unprognostic (4.09e-1)" "unprognostic (2.07e-2)" 158.1 7.2 1.6 9.4 1.8 11.2 155.2 2.7 2.3 4.1 35.9 1.5 3.8 5.6 4.5 7.8 8.6 4.3 7.2 12.6 1.7 1.1 15.6 7.4 11.3 4.5 1.6 1.6 4.9 11.8 2.5 4.2 11.6 1.8 5.2 1.5 1.9 8.1 8.1 25.0 6.1 23.1 3.0 2.1 4.9 8.2 4.0 1.5 1.5 11.3 4.8 5.1 13.0 18.6 4.2 6.5 18.7 8.5 3.6 5.3 3.6 10.4 8.2 1.7 4.4 64.1 5.7 11.0 11.1 9.0 7.0 6.2 6.9 10.5 6.2 6.6 8.3 9.4 2.5 4.6 2.1 7.9 22.7 8.5 3.6 11.1 21.0 5.8 10.8 11.2 6.0 4.7 5.4 5.7 7.2 6.3 6.2 6.1 7.8 12.9 4.9 17.6 7.6 3.7 13.8 6.8 2.4 6.3 8.4 20.6 17.6 6.4 7.5 6.8 10.2 6.3 4.9 4.1 5.0 24.3 15.0 5.2 15.8 8.4 4.4 9.3 8.5 18.7 3.6 5.5 3.5 4.2 4.6 5.2 5.7 3.6 5.3 4.3 7.7 3.6 6.0 6.5 3.9 3.6 1.6 1.8 2.7 1.9 1.7 1.1 1.6 1.6 1.8 1.5 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923739-43964488 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "liver: 31.1;retina: 39.3" "Cell line enhanced" "Detected in many" "AF22: 13.3;LHCN-M2: 15.0" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol Nucleoli "Mitochondria, Cytosol" "HPA058058: " "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.8 0.4 0.5 0.7 1.0 0.3 4.0 0.3 2.4 0.8 1.3 0.4 0.0 1.0 0.5 1.9 0.4 1.1 0.5 0.9 0.8 0.6 4.6 31.1 1.4 0.4 0.3 1.8 0.5 0.2 0.6 0.2 0.4 2.2 0.2 0.2 39.3 0.9 0.2 2.2 5.3 0.6 0.2 0.5 0.6 0.3 0.5 0.3 0.0 0.2 0.0 0.3 0.2 0.4 1.2 0.7 1.8 0.6 0.9 0.8 0.0 3.9 1.2 13.3 5.4 3.8 4.2 0.4 2.4 1.4 3.3 7.1 3.8 7.0 0.0 2.0 4.0 3.3 8.3 3.9 2.7 0.0 0.7 0.2 3.1 7.1 6.1 0.0 0.2 4.8 3.0 10.4 0.5 0.4 0.0 0.0 15.0 0.6 0.2 0.0 9.1 0.0 0.0 7.2 0.1 1.4 0.2 1.2 0.1 2.7 1.0 3.7 4.2 4.5 0.4 1.3 4.0 0.1 0.1 0.0 0.0 0.0 11.4 0.0 4.7 1.5 0.6 0.4 0.5 0.4 0.3 0.7 0.4 0.3 0.2 1.2 0.6 0.8 1.8 0.9 0.3 0.7 0.2 0.0 0.5 1.0 0.3 2.4 0.8 0.6 0.3 1.8 2.2 0.3 PNPLA4 "DXS1283E, GS2, iPLA2eta" ENSG00000006757 "Patatin like phospholipase domain containing 4" P41247 X 7898247-7927739 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" HPA003656 Approved "Intracellular and membrane" "HPA003656: AB_1079033" "unprognostic (2.97e-1)" "unprognostic (2.45e-1)" "unprognostic (4.17e-3)" "unprognostic (3.08e-2)" "prognostic unfavourable (5.29e-4)" "prognostic unfavourable (5.37e-4)" "unprognostic (3.15e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (6.30e-2)" "unprognostic (7.83e-2)" "unprognostic (2.27e-1)" "prognostic favourable (2.23e-12)" "unprognostic (5.23e-2)" "unprognostic (6.71e-3)" "unprognostic (6.30e-2)" "unprognostic (2.12e-1)" 11.3 18.1 12.6 6.0 18.8 4.7 13.9 5.0 11.5 8.9 8.9 8.5 13.3 11.2 9.2 11.4 13.2 15.0 6.2 24.0 10.9 11.9 26.5 39.8 5.8 6.3 12.0 8.7 14.0 21.0 13.3 17.0 4.7 12.2 8.0 7.5 13.1 18.9 10.7 40.9 10.8 10.5 7.4 11.2 5.4 11.5 7.8 10.6 7.2 23.6 21.1 8.9 6.6 9.5 13.2 18.3 7.6 10.4 9.0 10.3 8.4 18.6 7.6 1.2 19.3 0.4 0.2 5.2 5.8 0.6 10.1 6.2 7.7 6.9 5.9 0.0 1.9 11.0 0.0 19.5 17.3 0.2 13.7 4.2 14.8 16.1 12.8 7.3 6.2 13.2 20.0 5.1 12.1 7.0 16.4 0.2 0.1 4.9 0.1 7.2 20.4 16.3 0.1 0.1 6.5 13.3 8.5 11.1 5.6 17.6 7.3 9.9 11.3 5.5 4.0 0.1 5.1 15.5 0.1 8.9 0.1 11.1 0.1 0.1 1.6 5.2 9.8 7.6 5.4 10.4 6.2 12.3 7.8 5.9 18.3 13.2 10.3 9.8 0.7 9.0 9.7 13.5 4.8 8.4 12.6 18.8 5.0 11.5 10.9 11.9 12.0 8.7 12.2 10.6 PNPLA6 "iPLA2delta, NTE, SPG39, sws" ENSG00000032444 "Patatin like phospholipase domain containing 6" Q8IY17 19 7534004-7561764 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation, Dwarfism, Hereditary spastic paraplegia, Hypogonadotropic hypogonadism, Mental retardation, Neurodegeneration, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007522 Uncertain "HPA007522: AB_1079649" "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" "unprognostic (3.23e-2)" "unprognostic (2.78e-1)" "prognostic favourable (5.25e-4)" "unprognostic (3.53e-3)" "unprognostic (1.50e-1)" "unprognostic (2.07e-2)" "unprognostic (1.62e-1)" "prognostic favourable (3.51e-5)" "unprognostic (3.36e-1)" "prognostic favourable (7.53e-4)" "unprognostic (3.10e-3)" "unprognostic (3.50e-1)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" 12.9 19.7 25.9 25.0 29.3 22.3 17.8 22.1 35.8 10.2 15.9 26.1 10.0 26.3 13.7 6.3 16.4 12.6 14.0 12.0 22.6 19.1 17.1 13.7 30.4 17.6 36.3 19.2 12.5 14.2 15.6 21.6 13.9 29.2 13.4 8.9 15.8 13.7 14.3 27.0 15.3 28.7 14.5 23.5 28.3 12.2 31.3 33.0 7.1 14.7 6.1 8.8 15.9 14.7 3.8 7.3 21.8 19.0 5.0 3.9 4.1 13.0 31.6 6.2 15.0 10.9 15.8 14.4 17.0 17.5 13.3 12.3 7.4 18.1 10.8 29.0 22.0 16.8 5.3 16.0 6.9 26.3 12.2 7.1 16.9 5.5 12.6 7.9 22.3 13.7 9.3 17.1 9.9 26.1 5.8 14.9 11.8 6.2 8.7 10.4 6.8 29.0 7.0 3.7 12.7 11.8 12.5 7.9 13.7 14.5 6.6 18.5 5.8 11.4 27.6 16.1 9.5 22.1 17.8 17.7 11.4 4.8 27.1 9.4 15.1 7.9 6.1 21.8 3.5 12.1 3.5 3.8 2.5 3.8 7.3 2.8 2.2 2.9 1.9 5.0 19.0 2.4 3.9 4.1 25.9 29.3 22.1 35.8 22.6 19.1 36.3 19.2 29.2 33.0 PNPLA8 "IPLA2-2, IPLA2G, iPLA2gamma" ENSG00000135241 "Patatin like phospholipase domain containing 8" Q9NP80 7 108470422-108569666 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020083 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA020083: AB_1851849" "unprognostic (4.48e-2)" "unprognostic (3.37e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (4.61e-1)" "unprognostic (2.73e-2)" "unprognostic (3.48e-2)" "unprognostic (3.32e-1)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (2.49e-1)" "prognostic favourable (1.86e-6)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (4.28e-3)" "unprognostic (1.24e-1)" 21.5 35.7 29.3 12.4 28.9 51.5 15.0 15.6 27.2 15.4 13.4 9.5 9.3 8.6 13.4 13.7 18.3 9.7 15.9 17.9 23.0 22.1 23.1 24.6 16.7 12.0 20.7 17.5 15.6 10.1 20.7 33.4 25.2 23.2 14.4 11.4 6.0 11.4 13.9 29.8 11.4 10.8 15.3 20.3 19.5 11.1 10.8 21.1 16.1 22.6 13.0 15.3 22.5 12.8 20.0 19.3 16.7 26.8 14.6 12.5 13.7 14.0 6.3 11.2 10.0 25.0 17.2 16.6 13.4 23.7 11.0 18.4 6.1 8.1 7.8 16.9 13.1 5.3 19.0 8.5 16.8 11.7 5.2 5.3 10.4 4.5 18.3 3.7 11.1 15.6 16.2 14.8 13.7 14.8 6.3 22.5 13.7 9.2 8.6 8.8 4.9 9.0 3.2 11.8 16.6 13.2 17.8 9.3 13.1 12.8 13.9 16.0 5.8 6.3 12.0 18.2 8.1 27.0 7.3 19.1 19.3 11.6 17.3 5.7 11.7 14.1 19.7 16.7 10.5 21.8 12.5 20.0 10.3 10.3 19.3 18.7 11.2 10.7 16.5 14.6 26.8 7.6 12.5 13.7 29.3 28.9 15.6 27.2 23.0 22.1 20.7 17.5 23.2 21.1 PON1 "ESA, PON" ENSG00000005421 "Paraoxonase 1" P27169 7 95297676-95324707 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "liver: 144.1" "Cell line enhanced" "Detected in some" "A549: 1.4;RH-30: 1.0" "Cancer enriched" "Detected in some" 78 "liver cancer: 97.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001610 Approved "Secreted to blood" 96000000000 24000000000 "HPA001610: AB_1079656" "unprognostic (2.02e-2)" "unprognostic (2.41e-2)" "unprognostic (3.04e-1)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "prognostic favourable (7.24e-7)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (9.02e-3)" "unprognostic (1.76e-3)" "unprognostic (3.97e-2)" "unprognostic (6.74e-9)" "unprognostic (1.09e-3)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (5.54e-3)" 0.0 1.7 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 144.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 0.0 1.0 0.1 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.4 0.2 0.0 1.0 0.0 0.0 0.3 0.6 0.1 0.0 0.3 0.0 0.4 0.0 0.5 0.0 0.1 0.0 0.2 0.9 0.3 0.0 0.0 0.2 0.2 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.0 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 PON2 ENSG00000105854 "Paraoxonase 2" Q15165 7 95404863-95435329 "Candidate cardiovascular disease genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 81.0" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "myeloid DC: 22.1" "Lineage enriched" "Detected in many" 4 "dendritic cells: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025430, HPA029193" Enhanced "Secreted to blood" 350000000 "CAB025430: , HPA029193: AB_10602148" "unprognostic (1.43e-1)" "prognostic unfavourable (1.43e-5)" "unprognostic (3.80e-1)" "unprognostic (4.14e-1)" "unprognostic (3.89e-2)" "unprognostic (3.77e-3)" "unprognostic (1.19e-3)" "unprognostic (9.87e-3)" "unprognostic (9.54e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.80e-1)" "prognostic unfavourable (4.30e-8)" "unprognostic (1.40e-1)" "unprognostic (6.43e-2)" "unprognostic (7.99e-3)" "unprognostic (2.56e-1)" 17.0 42.2 54.1 7.5 59.1 3.3 23.1 25.4 52.2 16.5 24.0 29.7 7.4 28.2 16.6 22.7 10.2 15.0 18.9 13.1 57.2 31.4 23.9 81.0 33.1 4.5 41.4 31.0 10.6 7.2 10.9 15.0 34.3 34.8 14.7 31.1 9.9 8.5 17.2 4.3 19.4 19.1 18.4 44.2 7.3 8.8 9.6 40.1 1.8 13.6 5.1 11.2 13.7 8.1 0.9 22.1 0.5 5.2 5.0 3.5 3.0 9.6 60.4 49.1 26.6 6.9 15.2 13.8 19.7 23.1 15.4 16.8 13.6 22.0 0.0 27.6 19.4 6.5 8.9 15.1 17.5 0.1 11.7 4.9 36.3 45.0 10.9 0.0 6.8 22.0 17.5 8.2 11.3 31.7 3.1 0.2 45.2 8.8 0.0 5.4 9.6 14.0 0.0 23.2 2.3 47.5 7.5 3.4 10.6 28.1 31.4 18.9 9.2 3.1 34.5 23.1 16.8 7.7 18.9 5.2 6.0 0.0 21.6 4.5 30.1 0.0 5.2 0.5 3.5 2.6 3.1 0.9 1.3 3.2 22.1 0.4 1.9 2.4 0.0 5.0 1.2 5.3 0.6 3.0 54.1 59.1 25.4 34.3 57.2 31.4 41.4 31.0 34.8 40.1 PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359944-95396368 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 148.0" "Cell line enhanced" "Detected in some" "A549: 19.8;CACO-2: 6.4;CAPAN-2: 4.8;Hep G2: 21.9;T-47d: 12.3" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 12 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 12 "NK-cells: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014848, CAB025250" Enhanced "Secreted to blood" 1756666667 350000000 "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" 0.4 0.7 0.3 0.1 0.6 0.0 6.9 0.2 0.5 0.9 1.0 0.3 2.3 1.5 0.2 1.2 0.2 0.4 0.7 0.4 0.7 0.3 0.7 148.0 4.0 0.0 0.4 0.2 2.4 7.1 0.0 15.5 0.2 0.5 0.2 0.4 0.8 21.4 5.5 0.1 1.8 1.7 0.1 0.3 0.2 0.5 3.6 0.4 0.4 1.5 0.0 1.1 0.5 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 2.1 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 4.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 12.3 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.6 0.2 0.5 0.7 0.3 0.4 0.2 0.5 0.4 POP1 ENSG00000104356 "POP1 homolog, ribonuclease P/MRP subunit" Q99575 8 98117297-98159834 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066194 Supported Nucleoli Nucleoli "HPA066194: " "prognostic unfavourable (2.54e-4)" "unprognostic (9.42e-2)" "unprognostic (5.96e-3)" "unprognostic (3.31e-2)" "unprognostic (1.46e-1)" "unprognostic (7.46e-2)" "prognostic unfavourable (1.26e-6)" "prognostic unfavourable (9.88e-4)" "unprognostic (4.85e-1)" "unprognostic (1.47e-1)" "unprognostic (3.79e-1)" "unprognostic (1.39e-2)" "prognostic unfavourable (5.97e-4)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (2.96e-1)" 6.1 5.5 7.8 9.0 9.7 3.7 5.8 14.3 10.2 4.3 5.4 5.2 2.7 4.3 6.0 4.2 9.1 6.6 3.9 5.0 5.7 4.7 10.5 6.4 5.2 9.1 4.1 7.6 8.4 5.8 7.6 11.1 3.5 7.4 5.0 13.8 6.2 5.1 4.2 5.7 8.2 5.1 5.2 4.0 8.8 5.7 11.8 6.2 8.8 5.0 5.6 11.3 4.3 5.0 10.5 7.7 10.9 7.4 4.1 9.8 2.5 12.6 7.6 8.3 7.7 2.9 2.1 5.5 10.9 9.2 11.4 8.5 7.8 8.2 8.9 15.7 7.9 8.5 24.2 10.8 12.3 6.4 10.2 17.8 6.1 5.3 1.3 9.4 11.2 1.7 2.0 12.6 5.0 8.8 9.7 8.1 10.6 10.1 13.6 4.8 6.3 10.6 11.3 4.9 6.4 8.3 6.8 20.0 4.7 5.0 8.5 3.8 11.6 3.5 12.0 10.0 7.2 12.6 21.5 8.1 7.6 19.2 7.8 10.2 8.7 10.9 6.7 4.6 9.8 7.4 7.8 6.2 7.1 6.5 6.2 10.5 9.3 8.6 0.9 4.1 3.4 7.7 5.9 2.5 7.8 9.7 14.3 10.2 5.7 4.7 4.1 7.6 7.4 6.2 POP4 RPP29 ENSG00000105171 "POP4 homolog, ribonuclease P/MRP subunit" O95707 19 29604017-29617237 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042748 Approved "HPA042748: AB_10964774" "unprognostic (5.88e-2)" "unprognostic (2.78e-2)" "unprognostic (7.21e-2)" "unprognostic (4.00e-3)" "unprognostic (4.50e-2)" "unprognostic (5.73e-2)" "prognostic unfavourable (3.31e-4)" "unprognostic (8.35e-2)" "unprognostic (2.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.20e-2)" "unprognostic (9.47e-2)" "unprognostic (5.84e-2)" "unprognostic (4.21e-1)" "unprognostic (1.77e-2)" "unprognostic (5.23e-3)" "unprognostic (8.08e-3)" 23.7 17.1 14.6 14.5 15.8 13.6 11.1 14.1 18.9 8.9 19.4 14.0 10.5 13.8 15.5 11.8 15.1 12.1 9.5 17.7 13.8 12.8 21.0 22.9 10.4 12.7 14.7 14.4 11.0 15.7 10.6 10.0 15.2 14.7 12.8 7.7 13.6 17.3 10.6 29.1 12.2 17.1 11.0 15.1 15.7 15.3 17.2 8.0 17.8 18.0 16.2 16.3 11.6 10.0 28.9 27.0 35.3 34.2 23.3 35.2 26.9 16.9 30.1 2.9 2.4 3.9 2.1 11.5 16.1 2.1 4.9 5.0 13.4 4.3 14.6 28.3 3.3 8.0 4.5 5.2 1.9 32.4 27.9 17.0 9.7 8.3 4.2 19.5 9.0 2.3 3.4 3.7 2.0 3.9 14.8 4.2 3.7 17.8 11.6 3.8 4.8 16.0 7.8 20.0 7.4 2.6 7.8 7.0 6.9 16.7 7.7 8.0 6.8 5.7 11.5 6.2 18.5 9.4 14.1 13.9 26.0 18.0 7.3 10.8 5.7 35.3 27.0 26.4 26.7 34.2 19.0 28.9 25.5 28.4 27.0 23.6 20.9 25.3 16.4 23.3 26.7 22.0 35.2 26.9 14.6 15.8 14.1 18.9 13.8 12.8 14.7 14.4 14.7 8.0 POP5 ENSG00000167272 "POP5 homolog, ribonuclease P/MRP subunit" Q969H6 12 120578764-120581398 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047598, HPA069204" Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA047598: , HPA069204: " "unprognostic (1.50e-2)" "prognostic favourable (2.68e-5)" "unprognostic (1.55e-1)" "unprognostic (3.61e-3)" "unprognostic (3.81e-1)" "unprognostic (1.50e-1)" "unprognostic (4.80e-3)" "unprognostic (1.28e-1)" "unprognostic (7.34e-2)" "unprognostic (5.75e-2)" "unprognostic (4.13e-2)" "unprognostic (1.33e-1)" "prognostic unfavourable (4.85e-4)" "unprognostic (3.07e-1)" "unprognostic (6.21e-2)" "unprognostic (2.68e-1)" "unprognostic (5.68e-2)" 16.3 33.8 16.2 25.6 14.4 14.1 23.9 8.7 16.7 18.6 17.5 13.6 24.2 11.8 14.5 27.1 15.9 14.6 19.5 25.8 18.1 13.9 24.1 24.1 18.3 19.7 16.9 15.9 11.7 18.9 25.0 17.5 8.2 14.2 15.6 18.0 15.1 20.9 22.6 13.3 12.7 15.1 19.5 14.4 20.3 15.2 9.0 12.1 24.2 19.8 18.9 19.6 13.7 19.2 32.0 33.5 3.6 19.7 18.2 28.2 22.8 20.1 34.5 12.3 15.0 23.3 12.6 19.5 17.0 11.0 20.7 15.9 29.7 9.3 11.8 25.8 13.6 21.4 20.5 32.3 18.6 28.0 31.1 14.4 22.5 33.6 16.4 20.4 15.2 15.8 18.6 23.9 11.0 17.3 17.6 7.6 20.6 44.3 16.5 18.4 14.6 29.8 19.5 15.0 32.4 29.0 20.7 9.6 10.5 28.7 8.4 21.8 39.3 19.6 12.4 10.8 16.3 17.3 18.5 19.9 33.4 20.9 21.1 24.9 17.3 3.6 16.2 3.5 24.7 19.7 22.6 32.0 22.6 23.0 19.0 22.4 28.2 26.8 1.1 18.2 16.7 33.5 21.4 22.8 16.2 14.4 8.7 16.7 18.1 13.9 16.9 15.9 14.2 12.1 POP7 "RPP2, RPP20" ENSG00000172336 "POP7 homolog, ribonuclease P/MRP subunit" O75817 7 100706053-100707495 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021007 Uncertain Supported Nucleoli,Vesicles "Nucleoli, Vesicles" "HPA021007: AB_10963575" "unprognostic (3.19e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-1)" "prognostic unfavourable (4.99e-5)" "unprognostic (2.98e-2)" "unprognostic (2.28e-1)" "unprognostic (3.12e-2)" "unprognostic (9.50e-2)" "unprognostic (3.88e-1)" "prognostic unfavourable (6.02e-4)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (6.21e-2)" "unprognostic (6.73e-2)" 12.3 16.6 20.5 15.1 21.0 25.3 16.1 25.1 33.2 11.3 14.7 8.7 14.0 17.5 13.9 12.5 20.4 13.4 13.9 19.6 18.3 18.1 13.1 31.4 11.7 18.2 16.8 22.0 13.2 21.2 6.6 11.5 18.1 13.3 16.0 8.1 10.0 24.2 15.8 46.4 22.6 17.6 12.3 12.9 12.3 15.5 7.0 9.4 11.0 11.6 20.5 11.8 11.5 12.5 32.1 30.4 46.4 35.6 42.1 37.0 32.0 24.3 24.2 9.8 17.3 5.2 5.0 19.2 13.8 6.5 15.3 15.2 35.4 15.8 19.8 23.3 6.0 15.5 14.3 16.2 7.6 17.9 43.2 8.9 15.8 34.0 8.8 13.6 10.9 5.8 6.1 15.7 15.5 8.5 31.5 17.7 8.0 69.0 34.1 46.7 30.1 33.5 25.8 10.4 33.5 9.1 13.4 19.7 20.0 11.1 34.4 16.3 11.3 13.8 8.3 21.3 25.6 41.8 27.1 7.5 20.4 35.4 13.4 23.5 23.1 46.4 35.6 38.2 32.4 34.1 29.4 32.1 32.5 31.6 30.4 26.4 29.9 31.1 21.9 42.1 35.3 27.9 37.0 32.0 20.5 21.0 25.1 33.2 18.3 18.1 16.8 22.0 13.3 9.4 PPA1 "IOPPP, PP, PP1, Ppase, SID6-8061" ENSG00000180817 "Pyrophosphatase (inorganic) 1" Q15181 10 70202830-70233911 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019878, HPA020096" Supported Supported Vesicles 110000 Vesicles "HPA019878: AB_1855601, HPA020096: AB_1855600" "unprognostic (1.50e-1)" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.42e-1)" "unprognostic (4.47e-2)" "unprognostic (2.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-1)" "unprognostic (2.13e-2)" "unprognostic (3.60e-2)" "unprognostic (1.82e-3)" "unprognostic (5.36e-2)" "unprognostic (2.37e-1)" "unprognostic (3.53e-2)" "unprognostic (2.74e-1)" 46.6 55.5 41.3 36.8 56.0 24.2 88.7 66.8 62.2 34.8 45.7 25.2 43.7 33.2 30.4 59.6 48.6 38.1 31.5 30.0 46.7 54.2 40.7 59.0 39.1 54.6 74.3 47.5 17.9 72.6 23.3 29.5 34.6 60.7 24.4 53.4 26.1 36.8 42.1 37.0 24.6 41.0 32.8 72.7 22.4 32.5 25.1 47.2 20.4 52.0 35.8 44.4 32.7 40.2 21.5 48.9 1.0 17.7 15.5 35.6 25.3 58.1 24.1 21.6 63.6 58.8 51.9 20.2 21.8 41.0 34.2 36.1 73.4 30.9 84.3 19.9 21.7 47.1 63.2 42.5 35.0 79.2 60.1 23.0 24.4 41.9 37.1 56.6 14.6 34.0 50.9 27.4 73.1 41.3 53.6 45.4 32.2 34.1 54.7 53.2 22.5 66.9 33.5 24.7 49.3 71.3 36.6 64.9 21.8 24.0 94.1 18.6 23.5 25.5 18.7 9.5 36.2 31.2 41.3 15.0 32.8 61.7 14.7 79.5 8.3 0.0 17.7 0.4 13.3 13.8 35.6 21.5 30.8 23.1 48.9 13.8 34.2 28.9 1.0 15.5 14.5 11.3 30.1 25.3 41.3 56.0 66.8 62.2 46.7 54.2 74.3 47.5 60.7 47.2 PPA2 FLJ20459 ENSG00000138777 "Pyrophosphatase (inorganic) 2" Q9H2U2 4 105369077-105474081 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Approved Nucleoplasm,Mitochondria 8300 Mitochondria Nucleoplasm "HPA030888: , HPA031671: AB_10603986, HPA031672: AB_2673988" "prognostic unfavourable (2.98e-4)" "unprognostic (5.64e-2)" "prognostic favourable (6.60e-4)" "unprognostic (9.26e-3)" "unprognostic (2.93e-2)" "unprognostic (5.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "unprognostic (9.54e-2)" "prognostic favourable (1.27e-11)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" 9.2 18.0 18.4 17.2 15.4 24.0 20.6 12.3 17.6 10.2 19.8 9.3 20.3 18.1 13.3 20.7 14.8 10.7 18.7 42.5 15.6 15.3 23.7 21.2 23.1 34.8 17.2 12.1 9.5 25.0 10.4 15.0 9.3 15.4 16.1 16.7 12.6 21.4 26.8 29.6 15.0 16.8 22.8 12.4 12.1 15.0 9.7 10.7 9.4 14.3 28.2 10.6 12.2 9.5 20.0 35.3 14.7 20.8 22.0 17.0 14.6 11.5 5.5 10.7 18.1 6.8 5.5 7.8 6.5 8.6 8.0 5.7 12.1 17.0 9.5 8.7 5.3 5.8 21.4 10.3 9.5 13.4 7.6 8.5 8.9 11.0 5.4 20.1 8.2 5.3 10.7 5.5 4.3 7.7 14.1 13.1 7.3 14.6 17.1 14.5 7.8 18.7 15.2 6.6 9.3 26.5 8.9 11.0 6.6 4.5 26.7 9.4 14.0 16.4 4.1 5.8 11.3 6.2 11.3 11.6 14.6 9.9 10.1 10.9 7.8 14.7 15.0 9.7 15.3 20.8 13.3 20.0 16.0 16.2 35.3 16.6 15.5 17.0 6.4 22.0 16.2 17.7 15.9 14.6 18.4 15.4 12.3 17.6 15.6 15.3 17.2 12.1 15.4 10.7 PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.6;testis: 20.2" "Cell line enhanced" "Detected in some" "A549: 3.5;HeLa: 5.1;SH-SY5Y: 2.9;SK-MEL-30: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "myeloid DC: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" "Plasma membrane" "Cytokinetic bridge" "HPA034577: AB_10602817" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (9.85e-2)" "unprognostic (3.84e-2)" "unprognostic (5.00e-2)" "unprognostic (2.38e-1)" "unprognostic (3.43e-2)" "unprognostic (4.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.89e-1)" "unprognostic (1.10e-11)" "unprognostic (5.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" 0.1 0.5 3.1 0.2 6.4 1.4 3.9 0.2 10.6 0.2 0.2 0.1 0.0 0.1 0.3 0.9 0.2 0.2 0.3 0.3 1.9 1.0 0.3 0.1 0.4 0.3 1.7 6.9 0.2 0.2 0.1 0.7 1.0 0.2 0.5 0.1 0.0 0.3 0.6 0.1 0.7 0.1 0.2 10.5 0.3 0.1 20.2 0.0 0.1 0.4 0.0 0.3 0.4 0.1 0.2 1.3 0.0 0.9 0.0 0.0 0.2 0.0 3.5 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 1.2 0.0 5.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.1 6.4 0.2 10.6 1.9 1.0 1.7 6.9 0.2 0.0 PPEF2 PPP7CB ENSG00000156194 "Protein phosphatase with EF-hand domain 2" O14830 4 75859864-75902571 "Enzymes, Predicted intracellular proteins" "Sensory transduction, Vision" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "retina: 75.7" "Cell line enhanced" "Detected in single" "hTCEpi: 1.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (3.19e-2)" "unprognostic (2.92e-1)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (1.53e-1)" "unprognostic (9.02e-2)" "unprognostic (3.32e-4)" "unprognostic (2.74e-2)" "unprognostic (4.54e-8)" "unprognostic (2.89e-1)" "unprognostic (5.98e-2)" "unprognostic (5.16e-1)" "unprognostic (3.66e-3)" 0.1 0.0 0.0 0.2 0.4 0.2 0.3 3.1 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.3 75.7 0.0 0.0 0.3 0.4 0.1 0.1 0.1 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 3.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 PPM1A "MGC9201, PP2CA, PP2Calpha" ENSG00000100614 "Protein phosphatase, Mg2+/Mn2+ dependent 1A" P35813 14 60245752-60299087 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029209 Approved Supported "Plasma membrane,Cytosol" 850000 Cytosol "Plasma membrane" "HPA029209: " "unprognostic (3.14e-1)" "unprognostic (2.14e-1)" "unprognostic (5.64e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-2)" "unprognostic (2.30e-2)" "unprognostic (4.50e-2)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.29e-1)" "prognostic favourable (1.57e-9)" "unprognostic (1.58e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" 16.2 11.7 13.8 15.0 18.3 64.0 15.1 20.5 28.6 15.5 32.4 13.3 9.4 19.1 17.4 12.7 15.2 10.7 10.8 37.1 13.5 16.1 22.8 26.7 14.6 11.8 15.6 19.1 12.1 13.3 18.2 12.2 15.8 24.3 16.5 19.4 12.3 18.7 13.5 56.1 16.7 25.2 15.0 13.8 11.6 14.9 29.7 12.7 23.4 13.3 11.6 13.4 15.2 16.5 4.0 2.7 8.0 2.1 4.7 4.5 1.9 47.8 10.8 9.4 8.0 14.4 13.4 12.0 13.2 15.5 9.8 9.3 6.1 14.1 28.8 12.6 14.9 10.7 9.7 13.6 17.2 25.9 5.5 17.7 7.7 9.5 12.1 20.0 12.7 11.3 16.3 11.5 15.8 9.6 9.8 23.0 11.9 21.0 26.0 4.7 8.8 9.1 9.4 21.8 9.3 11.8 23.0 16.0 12.0 13.7 16.0 11.1 16.1 8.8 13.2 20.5 20.5 8.9 9.3 17.9 10.1 33.7 9.4 7.9 10.3 6.7 1.8 5.1 3.5 1.8 3.8 1.7 2.8 3.1 2.7 4.0 2.2 2.1 8.0 4.7 2.1 1.6 4.5 1.9 13.8 18.3 20.5 28.6 13.5 16.1 15.6 19.1 24.3 12.7 PPM1B "PP2CB, PP2CBETA, PPC2BETAX" ENSG00000138032 "Protein phosphatase, Mg2+/Mn2+ dependent 1B" O75688 2 44167969-44244384 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016745 Approved Approved Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA016745: AB_1855622" "unprognostic (5.49e-2)" "unprognostic (2.67e-2)" "unprognostic (1.11e-2)" "unprognostic (2.96e-3)" "unprognostic (1.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-2)" "unprognostic (1.58e-1)" "unprognostic (1.94e-1)" "unprognostic (2.25e-1)" "unprognostic (6.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (1.75e-2)" 23.7 13.8 31.2 12.2 33.8 24.7 15.2 32.6 25.2 16.3 18.2 26.0 13.6 13.2 15.7 20.4 14.9 12.7 14.3 21.1 29.6 24.6 19.4 27.7 13.4 16.6 34.6 22.4 15.8 20.9 34.6 17.9 12.1 22.9 20.7 19.0 24.3 16.4 16.4 72.0 12.5 14.3 21.1 27.3 16.1 14.8 13.3 34.1 19.1 15.0 13.1 16.8 18.2 15.9 6.5 5.5 11.1 5.0 4.7 9.5 1.6 17.3 15.5 20.7 15.1 25.9 12.1 23.5 13.5 15.6 14.0 12.4 20.9 11.3 19.1 21.2 15.5 9.5 23.1 8.8 20.8 19.3 9.0 20.2 9.3 14.3 20.9 18.0 16.9 11.6 15.5 11.1 18.9 11.4 14.7 20.3 12.5 14.4 17.8 29.0 25.5 5.2 19.0 23.1 12.8 32.6 17.6 16.7 21.0 12.1 18.2 15.6 9.8 12.6 10.4 12.3 17.7 10.1 12.9 17.8 11.6 17.9 6.5 30.0 8.8 8.3 3.3 11.1 7.2 4.5 6.2 5.8 6.9 6.1 5.5 6.5 9.5 6.4 9.2 4.7 5.0 5.3 6.2 1.6 31.2 33.8 32.6 24.9 29.6 24.6 34.6 22.4 22.9 34.1 PPM1D "PP2C-DELTA, Wip1" ENSG00000170836 "Protein phosphatase, Mg2+/Mn2+ dependent 1D" O15297 17 60600183-60666280 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022277 Approved Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA022277: AB_1858839" "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "prognostic favourable (3.52e-4)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (5.12e-2)" "prognostic unfavourable (4.27e-4)" "unprognostic (5.50e-2)" "unprognostic (1.70e-2)" "unprognostic (6.07e-2)" "unprognostic (2.52e-3)" "unprognostic (3.46e-2)" "unprognostic (1.95e-3)" "unprognostic (7.33e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (1.98e-1)" 12.2 7.0 6.1 5.7 9.2 13.6 11.9 30.8 6.6 11.1 10.0 10.6 7.8 7.6 12.0 8.3 8.6 11.1 8.3 5.8 7.7 4.4 7.4 7.4 9.2 7.9 10.3 4.6 17.3 12.3 8.1 8.9 18.5 8.8 9.3 9.4 8.2 8.1 6.8 9.7 8.1 8.1 8.2 7.3 9.2 7.3 16.2 12.5 15.5 8.7 6.9 7.0 7.8 11.3 7.3 13.1 20.5 13.2 6.8 8.3 6.8 2.7 5.4 6.1 5.2 4.1 2.5 7.9 4.3 2.8 2.8 4.0 5.5 1.6 7.8 3.5 2.9 2.9 3.9 1.8 3.8 1.4 8.7 5.6 5.4 6.4 3.4 2.2 4.3 2.2 2.9 4.1 2.4 6.3 4.1 3.3 3.0 26.5 6.1 3.4 2.6 4.2 7.4 7.8 4.7 2.5 3.4 8.4 6.1 5.7 1.9 1.3 2.3 3.0 4.6 3.6 10.0 2.8 2.3 5.3 5.6 5.9 1.4 2.3 2.8 8.2 13.2 14.1 6.7 10.2 5.9 7.3 5.6 6.1 13.1 5.9 6.1 6.2 20.5 6.8 6.1 5.8 8.3 6.8 6.1 9.2 30.8 6.6 7.7 4.4 10.3 4.6 8.8 12.5 PPM1E "CaMKP-N, KIAA1072, POPX1, PP2CH" ENSG00000175175 "Protein phosphatase, Mg2+/Mn2+ dependent 1E" Q8WY54 17 58755869-58985176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 10.7;brain: 36.5;testis: 13.1" "Cell line enhanced" "Detected in some" "AF22: 10.0;HAP1: 16.2;MOLT-4: 7.6;SCLC-21H: 7.5;SH-SY5Y: 15.5;THP-1: 6.9" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 25 "basophil: 2.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018462, HPA019263" Approved Approved Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA018462: AB_1855623, HPA019263: AB_1855624" "unprognostic (2.50e-2)" "unprognostic (5.75e-2)" "unprognostic (8.12e-2)" "unprognostic (2.99e-2)" "unprognostic (5.30e-1)" "unprognostic (8.19e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (3.22e-2)" "unprognostic (5.24e-2)" "unprognostic (8.80e-5)" "unprognostic (4.97e-2)" "unprognostic (1.23e-7)" "unprognostic (1.05e-4)" "unprognostic (1.64e-2)" "unprognostic (1.27e-1)" "unprognostic (9.12e-2)" 0.7 10.7 15.0 0.8 7.5 0.7 0.7 11.9 23.3 1.0 0.7 3.6 0.0 0.8 1.1 2.2 0.7 3.3 0.8 2.3 36.5 5.4 1.9 2.4 1.0 0.9 3.2 9.2 1.0 1.7 0.8 3.4 0.6 10.5 3.2 0.7 3.5 0.8 0.7 0.6 0.7 1.0 1.3 2.7 0.8 1.4 13.1 2.0 0.0 0.8 0.0 1.0 0.6 0.6 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.5 0.0 0.0 0.7 0.0 0.0 0.8 1.1 0.0 0.0 6.3 0.1 0.1 0.0 16.2 0.0 0.4 0.1 4.8 0.0 0.1 0.0 1.1 0.5 2.1 0.3 1.3 0.0 0.0 0.0 1.6 0.0 0.0 2.8 7.6 0.0 2.8 0.8 0.0 1.3 0.0 0.0 0.0 7.5 15.5 0.2 0.0 1.0 0.0 6.9 0.0 0.0 1.9 0.0 2.3 0.0 0.1 4.3 0.2 0.0 2.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 7.5 11.9 14.0 36.5 5.4 3.2 9.2 10.5 2.0 PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919420-21952837 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 17.7" "Group enriched" "Detected in many" 7 "dendritic cells: 5.5;granulocytes: 17.7;monocytes: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" 780000 Nucleoplasm "Plasma membrane" "HPA030989: AB_10669549, HPA030990: AB_10601249" "unprognostic (6.26e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (2.51e-1)" "unprognostic (4.77e-3)" "unprognostic (4.88e-3)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-2)" "unprognostic (1.45e-2)" "unprognostic (4.81e-2)" "prognostic unfavourable (6.03e-5)" "unprognostic (6.44e-2)" "unprognostic (3.02e-2)" "unprognostic (3.30e-1)" "unprognostic (4.11e-2)" 25.0 15.6 14.0 21.8 14.3 24.3 18.4 16.9 16.3 18.1 13.2 7.6 12.5 9.6 17.6 9.7 23.6 12.3 13.1 17.0 13.9 14.9 13.2 8.5 21.6 15.1 11.6 10.1 14.4 10.7 8.3 7.7 28.1 14.5 15.6 4.9 11.2 11.2 16.5 15.8 15.5 11.1 15.4 15.5 31.4 10.5 6.7 10.9 6.2 10.9 15.1 10.2 15.8 37.6 0.7 5.5 17.7 13.9 1.7 1.4 2.8 9.1 9.8 6.3 6.1 3.5 6.2 7.9 10.4 6.2 9.2 6.3 4.4 3.7 5.5 13.0 7.3 11.0 2.7 6.4 3.3 7.8 8.8 21.3 4.5 4.2 5.8 7.8 5.8 5.8 1.9 9.0 4.2 35.8 54.2 2.3 11.8 8.4 4.6 6.1 2.6 10.7 7.0 16.2 1.6 3.1 3.9 2.5 9.8 9.9 3.3 8.5 4.1 5.5 30.1 11.1 11.3 10.1 9.9 4.6 3.7 6.1 11.2 15.0 21.2 0.0 7.7 3.3 1.0 12.9 0.7 0.7 0.7 0.6 5.5 0.6 0.7 0.8 17.7 1.7 13.9 1.4 1.4 2.8 14.0 14.3 16.9 16.3 13.9 14.9 11.6 10.1 14.5 10.9 PPM1G "PP2CG, PP2Cgamma" ENSG00000115241 "Protein phosphatase, Mg2+/Mn2+ dependent 1G" O15355 2 27381194-27409687 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.3" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035530, HPA035531" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA035530: AB_10670021, HPA035531: AB_10610283" "unprognostic (7.50e-2)" "unprognostic (8.89e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (2.27e-1)" "unprognostic (4.15e-2)" "prognostic unfavourable (3.14e-7)" "unprognostic (9.36e-3)" "unprognostic (7.73e-2)" "prognostic favourable (6.08e-5)" "unprognostic (3.74e-2)" "unprognostic (1.23e-1)" "unprognostic (7.46e-3)" "unprognostic (1.06e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (7.83e-2)" 12.7 17.0 9.9 19.9 9.2 19.4 30.2 10.9 19.3 17.9 14.6 9.1 16.9 12.1 26.8 12.5 19.4 19.2 17.7 13.6 8.8 7.6 12.6 18.6 14.7 20.2 9.4 8.0 13.4 18.6 13.8 13.2 11.4 8.7 10.2 16.4 9.1 16.4 18.7 24.1 10.9 12.2 14.9 6.7 14.7 14.1 93.3 8.4 25.8 14.1 19.1 22.5 25.2 17.3 20.2 40.3 24.5 29.1 22.7 38.3 19.0 50.1 41.4 30.4 23.4 19.4 15.8 28.1 31.3 20.6 37.6 30.2 63.7 26.6 59.2 23.0 22.2 27.5 51.1 35.2 33.8 24.7 41.5 57.6 30.2 67.3 17.5 56.9 24.4 17.1 20.4 38.3 30.9 35.9 48.2 18.4 28.5 44.9 42.2 61.7 44.2 29.9 43.7 63.7 31.1 25.3 35.0 40.9 46.3 28.1 31.1 22.4 17.2 18.7 28.8 28.2 34.1 24.6 47.4 40.2 45.0 93.6 22.0 46.6 21.1 22.1 17.8 24.5 26.9 22.3 26.5 20.2 28.7 27.9 28.5 18.0 21.7 22.4 9.1 22.7 29.1 40.3 38.3 19.0 9.9 9.2 10.9 19.3 8.8 7.6 9.4 8.0 8.7 8.4 PPM1H "ARHCL1, FLJ13253, KIAA1157, NERPP-2C" ENSG00000111110 "Protein phosphatase, Mg2+/Mn2+ dependent 1H" Q9ULR3 12 62643982-62935037 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;parathyroid gland: 36.6" "Cell line enhanced" "Detected in many" "CACO-2: 35.1;HMC-1: 28.3;SK-BR-3: 16.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 5.3" "Group enriched" "Detected in many" 11 "dendritic cells: 2.3;granulocytes: 5.3;monocytes: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020694, HPA044244, HPA058777" Approved Supported Nucleoplasm Nucleoplasm "CAB020694: , HPA044244: , HPA058777: " "unprognostic (3.41e-2)" "unprognostic (1.94e-1)" "unprognostic (9.51e-2)" "unprognostic (8.61e-3)" "unprognostic (1.44e-1)" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (5.85e-2)" "unprognostic (3.17e-1)" "unprognostic (1.78e-2)" "unprognostic (5.53e-3)" "unprognostic (2.19e-1)" "prognostic favourable (2.72e-5)" "unprognostic (3.90e-2)" "unprognostic (1.73e-1)" "unprognostic (8.04e-3)" "unprognostic (1.14e-1)" 2.6 2.1 10.6 1.6 12.4 3.1 5.7 37.1 16.3 8.5 2.8 14.0 12.4 3.6 6.9 7.7 1.1 7.5 9.1 2.2 13.0 12.2 11.7 3.9 3.2 1.5 14.3 9.0 9.4 4.9 36.6 13.3 7.1 8.5 15.0 3.6 7.7 10.2 11.6 1.5 1.2 2.1 2.2 8.9 1.3 6.2 1.4 15.0 0.5 3.8 0.1 2.1 3.4 1.2 0.0 2.3 5.3 1.7 0.2 0.0 0.3 0.5 5.4 1.0 0.0 0.2 0.0 11.9 1.3 1.3 0.8 0.2 35.1 2.5 0.0 1.2 0.6 0.7 3.8 0.1 0.5 0.1 1.9 6.6 1.0 7.9 0.0 2.0 28.3 0.0 0.1 0.0 0.3 0.1 1.7 0.0 0.6 4.0 0.6 0.9 7.1 2.6 0.9 2.5 9.8 8.1 12.4 3.1 0.0 2.2 16.0 5.2 8.7 1.1 0.1 0.2 0.7 0.1 0.4 1.4 9.0 1.8 0.1 0.0 0.5 5.3 1.7 3.0 0.0 1.4 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 1.2 0.2 1.4 0.0 0.0 0.3 10.6 12.4 37.1 16.3 13.0 12.2 14.3 9.0 8.5 15.0 PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715477 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 30.9;skeletal muscle: 45.1;testis: 31.9" "Cell line enhanced" "Detected in many" "T-47d: 20.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 9 "plasmacytoid DC: 30.9" "Lineage enriched" "Detected in many" 17 "dendritic cells: 30.9" "Region enriched" "Detected in some" 8 "olfactory region: 33.6" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles Vesicles "HPA046045: " "unprognostic (8.68e-2)" "unprognostic (5.65e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.93e-3)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-2)" "unprognostic (2.55e-1)" "unprognostic (9.30e-3)" "unprognostic (3.36e-2)" "unprognostic (7.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.28e-2)" "unprognostic (9.96e-4)" 0.8 2.3 6.4 0.9 4.8 0.8 1.9 7.8 6.8 0.9 0.7 2.1 1.6 0.7 1.4 14.8 3.0 2.4 1.3 5.4 4.3 4.8 1.2 0.7 0.7 2.4 3.7 4.4 1.3 3.8 2.4 1.1 0.8 3.9 1.4 0.7 1.5 2.3 2.3 45.1 13.3 0.6 1.3 1.6 1.3 0.7 31.9 0.7 1.4 1.6 5.3 1.9 1.6 1.5 0.4 30.9 0.0 1.7 0.0 0.0 0.3 2.7 0.1 1.5 1.7 0.8 1.6 1.2 0.3 0.7 0.3 1.0 1.2 0.8 0.4 0.5 0.8 5.0 1.1 4.6 0.4 0.0 2.7 0.8 0.2 0.1 1.0 0.0 0.2 1.8 3.1 0.9 4.8 2.1 1.0 0.0 1.2 2.8 0.0 0.0 1.7 2.3 0.1 0.2 0.0 2.8 0.1 0.8 0.2 0.6 4.5 1.3 20.0 0.0 1.2 0.3 2.9 0.0 0.2 0.1 0.0 0.0 2.4 0.6 2.7 0.0 0.1 0.0 0.0 0.6 0.0 0.3 0.0 0.0 3.2 0.4 0.0 0.0 0.0 0.0 1.7 30.9 0.0 0.3 6.4 4.8 7.8 6.8 4.3 4.8 3.7 4.4 3.9 0.7 PPM1K "BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm" ENSG00000163644 "Protein phosphatase, Mg2+/Mn2+ dependent 1K" Q8N3J5 4 88257620-88284769 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 59.1" "Cell line enhanced" "Detected in many" "Daudi: 27.1;Karpas-707: 23.6;U-698: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020066, HPA020862, HPA023891" Approved Supported Mitochondria Mitochondria "HPA020066: AB_1855628, HPA020862: AB_1855629, HPA023891: AB_1855630" "unprognostic (2.38e-2)" "unprognostic (5.86e-2)" "unprognostic (7.42e-3)" "unprognostic (6.70e-3)" "unprognostic (1.18e-1)" "unprognostic (1.17e-3)" "unprognostic (1.87e-1)" "unprognostic (5.88e-2)" "unprognostic (5.50e-2)" "unprognostic (1.41e-2)" "unprognostic (9.25e-3)" "unprognostic (6.56e-2)" "unprognostic (9.82e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" 3.6 6.1 19.2 8.8 17.2 5.9 9.3 21.1 26.8 12.9 3.8 12.5 2.5 3.0 21.8 5.5 7.6 14.1 6.0 59.1 23.1 14.6 11.8 5.1 6.5 14.5 21.6 15.9 22.0 7.3 10.4 8.4 6.4 17.0 11.1 4.3 4.7 7.1 5.3 8.3 1.9 6.7 18.2 15.0 10.9 5.4 12.3 19.4 7.3 5.4 1.9 15.8 6.5 8.1 31.8 38.8 5.5 3.4 7.9 16.1 7.1 2.1 0.7 2.8 4.9 4.2 5.5 1.1 3.4 6.3 11.6 13.7 5.6 0.5 27.1 3.8 2.2 0.2 8.2 2.6 4.6 20.9 3.4 4.8 2.1 5.0 3.3 6.6 2.6 3.6 1.3 7.1 6.2 1.9 7.2 23.6 3.3 3.1 8.7 3.6 1.7 1.1 5.0 4.6 10.3 4.0 0.9 2.2 1.9 2.1 0.2 2.5 11.2 1.8 0.3 4.0 2.1 1.3 2.0 7.4 6.8 22.7 4.4 5.4 6.7 5.5 2.9 2.3 12.4 3.4 16.1 30.4 11.8 12.4 5.5 31.8 11.7 14.1 0.9 7.9 0.9 38.8 13.3 7.1 19.2 17.2 21.1 26.8 23.1 14.6 21.6 15.9 17.0 19.4 PPM1L PP2CE ENSG00000163590 "Protein phosphatase, Mg2+/Mn2+ dependent 1L" Q5SGD2 3 160755602-161078907 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HDLM-2: 34.9;U-266/70: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 7.6" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019891, HPA019953" Approved Approved Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA019891: AB_1855631, HPA019953: AB_2170360" "prognostic unfavourable (4.90e-4)" "unprognostic (7.29e-3)" "unprognostic (2.01e-1)" "unprognostic (2.59e-2)" "unprognostic (8.03e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (1.63e-2)" "unprognostic (2.49e-2)" "unprognostic (1.92e-1)" "unprognostic (4.51e-2)" "unprognostic (7.51e-2)" "unprognostic (2.69e-3)" "unprognostic (1.81e-1)" "unprognostic (2.39e-1)" "unprognostic (9.13e-3)" "unprognostic (2.07e-1)" 7.7 8.5 7.4 3.5 11.5 3.3 6.3 15.8 23.2 11.3 7.0 5.5 1.1 3.0 6.2 3.7 8.7 6.1 12.6 9.9 6.3 7.8 8.4 6.0 4.6 1.9 8.0 10.1 3.7 5.4 33.6 26.3 11.5 13.8 9.6 5.9 5.6 18.9 3.7 25.7 7.6 3.6 16.4 4.6 3.4 8.4 2.8 3.7 5.6 14.4 9.6 3.5 16.6 10.8 0.7 1.3 4.9 7.6 1.1 2.6 2.0 1.1 0.7 4.0 2.1 2.3 0.0 2.5 0.2 0.1 0.4 0.1 0.2 0.2 0.2 0.4 0.1 3.6 3.3 0.2 0.1 34.9 3.5 3.4 3.3 0.4 0.1 2.1 4.0 0.4 1.6 0.1 0.2 0.2 0.1 5.5 0.0 1.8 0.8 0.2 2.3 0.8 4.1 0.7 0.8 0.1 3.7 4.8 4.1 2.0 2.3 0.1 2.7 2.1 0.2 0.4 0.4 0.3 1.3 34.9 0.1 1.9 0.6 1.7 0.8 0.7 2.3 4.9 2.6 5.5 0.2 0.2 0.6 1.7 1.3 0.7 1.0 1.8 0.2 1.1 7.6 0.8 0.0 2.0 7.4 11.5 15.8 17.9 6.3 7.8 8.0 10.1 13.8 3.7 PPM1M "FLJ32332, PP2Ceta" ENSG00000164088 "Protein phosphatase, Mg2+/Mn2+ dependent 1M" Q96MI6 3 52245793-52250597 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.0;U-266/70: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA036905, HPA062291" Uncertain Approved "Nuclear bodies" "Nuclear bodies" "HPA036905: AB_10602818, HPA062291: " "unprognostic (4.26e-3)" "prognostic favourable (7.73e-4)" "unprognostic (2.55e-2)" "unprognostic (4.85e-3)" "unprognostic (5.64e-2)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "prognostic favourable (6.69e-4)" "unprognostic (4.63e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "prognostic unfavourable (1.61e-5)" "unprognostic (1.49e-1)" "unprognostic (4.14e-2)" "unprognostic (9.27e-2)" "unprognostic (4.37e-2)" 14.3 7.2 13.9 22.7 14.8 16.5 26.3 3.6 9.2 16.9 12.5 4.6 7.8 4.4 13.6 12.0 10.8 11.7 19.4 14.5 8.7 8.5 8.7 4.9 30.1 38.0 5.4 12.3 14.9 5.9 6.9 7.5 8.6 4.9 15.1 6.7 11.0 10.8 12.4 3.1 7.5 8.8 18.1 6.8 22.5 8.3 6.2 5.9 20.5 11.3 9.9 20.5 11.3 13.5 5.0 9.6 19.6 18.6 7.4 15.0 10.1 0.4 2.5 1.6 3.7 22.9 23.0 2.5 5.8 12.6 8.3 6.4 1.5 2.0 4.2 1.7 15.2 0.7 5.2 1.1 3.4 5.1 1.2 9.6 6.7 1.5 16.8 1.4 9.2 18.9 2.5 9.2 5.8 10.6 1.6 7.0 9.6 1.0 6.3 0.4 2.0 7.1 1.4 0.7 9.3 3.6 1.1 1.1 4.6 4.2 1.1 5.2 3.6 3.7 7.4 3.1 5.3 1.8 0.7 26.3 4.9 4.5 6.3 2.5 3.8 1.2 15.7 8.5 15.0 12.4 11.7 5.0 11.8 13.8 9.6 3.8 11.1 13.8 19.6 7.4 18.6 5.8 13.2 10.1 13.9 14.8 3.6 9.2 8.7 8.5 5.4 12.3 4.9 5.9 PPM1N FLJ40125 ENSG00000213889 "Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)" Q8N819 19 45488777-45502510 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood: 43.7;skeletal muscle: 81.9" "Cell line enhanced" "Detected in many" "RT4: 21.8" "Cancer enhanced" "Detected in many" "testis cancer: 11.3" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "non-classical monocyte: 43.7" "Lineage enriched" "Detected in all" 10 "monocytes: 43.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA043577 Supported Vesicles Vesicles "HPA043577: " "unprognostic (2.38e-2)" "unprognostic (1.11e-2)" "unprognostic (8.53e-2)" "unprognostic (6.59e-2)" "unprognostic (4.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-3)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.45e-2)" "unprognostic (9.27e-2)" "unprognostic (2.48e-2)" "unprognostic (1.11e-16)" "unprognostic (3.42e-2)" "unprognostic (1.79e-1)" "unprognostic (3.92e-2)" "unprognostic (1.86e-3)" 1.7 0.9 5.4 1.2 4.5 1.3 1.9 0.7 4.1 1.3 1.7 0.1 0.7 0.6 1.5 1.0 2.2 0.8 1.0 0.9 3.3 2.3 1.2 1.5 1.5 1.6 2.6 2.2 0.8 0.5 1.3 1.4 2.4 2.7 2.3 1.0 10.6 1.5 1.4 81.9 2.4 1.4 2.6 3.4 15.7 1.7 2.9 3.5 2.5 0.9 0.0 2.4 4.0 1.9 1.9 4.3 2.3 43.7 1.1 2.9 1.9 1.9 5.1 0.9 3.9 4.5 6.1 11.2 1.4 2.3 0.4 1.7 1.3 12.0 8.1 2.4 1.3 5.7 2.3 1.7 0.7 7.9 3.3 6.4 2.0 1.5 1.1 0.5 13.7 2.5 2.6 2.3 1.3 0.7 7.3 7.3 0.8 1.4 2.2 3.5 3.1 1.1 1.4 1.1 2.3 2.5 21.8 4.4 5.2 0.7 8.4 6.3 2.8 1.9 1.1 6.4 3.9 3.1 1.0 1.2 3.2 1.6 4.7 1.7 5.5 1.7 1.6 1.0 2.2 7.2 2.0 1.9 1.4 2.2 4.3 1.3 1.6 2.9 2.3 1.1 43.7 0.8 1.5 1.9 5.4 4.5 0.7 4.1 3.3 2.3 2.6 2.2 2.7 3.5 PPME1 PME-1 ENSG00000214517 "Protein phosphatase methylesterase 1" Q9Y570 11 74171099-74254703 "Enzymes, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 69.0" "Cell line enhanced" "Detected in all" "RH-30: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004541, HPA043900, HPA064396" Enhanced Supported "Nucleoplasm,Nuclear bodies" 16000 Nucleoplasm "Nuclear bodies" "CAB004541: AB_628161, HPA043900: , HPA064396: " "unprognostic (2.99e-2)" "unprognostic (1.27e-2)" "unprognostic (2.28e-1)" "unprognostic (1.98e-1)" "unprognostic (9.26e-2)" "unprognostic (5.77e-3)" "prognostic unfavourable (4.45e-6)" "unprognostic (2.31e-2)" "unprognostic (7.92e-2)" "unprognostic (9.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.06e-1)" "prognostic unfavourable (2.76e-4)" "unprognostic (1.84e-1)" "unprognostic (1.54e-1)" "unprognostic (4.14e-3)" "unprognostic (1.33e-3)" 9.4 16.1 13.3 6.2 27.6 8.4 9.3 27.4 38.5 11.4 9.2 13.5 9.4 7.1 13.1 16.5 13.5 15.2 8.9 12.8 14.6 18.3 12.3 6.5 8.2 5.5 13.6 18.6 12.4 10.4 69.0 13.6 15.5 22.4 15.1 9.8 9.6 11.9 15.9 21.0 16.2 7.4 13.4 12.7 5.0 8.3 22.9 9.3 8.6 14.9 7.9 8.5 11.4 10.2 7.5 11.3 10.9 9.6 12.2 14.0 8.4 9.9 13.0 8.9 9.4 9.3 7.7 8.8 14.6 9.6 27.7 22.0 28.6 6.6 5.3 10.2 10.8 16.6 13.2 10.0 26.1 7.4 5.0 7.9 14.1 12.2 18.6 5.7 7.0 7.4 8.2 14.7 6.4 8.1 18.4 4.5 48.4 6.6 6.7 6.1 7.0 10.4 8.0 90.6 8.0 10.4 6.9 12.2 10.4 17.5 8.0 20.5 14.7 5.9 4.9 11.1 13.3 10.6 11.2 8.5 10.8 9.4 8.2 5.2 9.0 1.3 8.6 10.9 10.8 9.6 13.3 6.9 13.8 12.7 10.8 7.5 14.0 11.2 5.0 12.2 8.5 11.3 9.7 8.4 13.3 27.6 27.4 38.5 14.6 18.3 13.6 18.6 22.4 9.3 PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398183-67421183 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 177.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" 8100000 "Nucleoplasm, Plasma membrane, Cytosol" "CAB004545: AB_628177, HPA046833: " "unprognostic (1.03e-1)" "unprognostic (5.82e-3)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (3.15e-3)" "unprognostic (3.93e-2)" "unprognostic (2.07e-1)" "unprognostic (3.89e-2)" "unprognostic (5.05e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.96e-2)" "unprognostic (7.69e-2)" "prognostic favourable (1.17e-4)" "unprognostic (7.60e-2)" 28.4 35.4 24.2 42.0 32.3 42.1 25.1 19.6 33.4 23.9 39.6 22.1 29.9 33.9 19.6 25.8 59.7 22.8 28.6 33.0 21.8 17.1 43.7 55.0 27.6 49.3 19.9 19.9 20.1 53.3 23.1 21.6 44.0 19.3 27.2 33.2 23.2 49.7 31.1 39.0 34.4 47.3 20.5 21.3 53.7 35.1 15.7 19.4 77.7 38.5 40.5 63.9 25.5 25.7 78.8 76.6 126.2 118.0 68.2 113.9 177.2 46.2 53.4 31.7 46.6 15.8 19.4 32.3 22.9 26.9 46.3 35.2 76.3 55.9 39.8 39.1 34.8 40.5 36.6 47.7 28.5 41.8 24.8 38.2 25.2 40.0 34.5 48.5 49.4 21.8 31.6 39.4 23.2 46.4 35.5 33.0 37.4 105.5 61.5 95.4 52.5 42.3 43.7 43.9 34.5 45.4 38.3 24.8 41.2 26.6 47.8 70.7 57.2 33.6 33.0 35.7 36.6 42.1 29.6 33.1 30.6 45.2 42.8 33.4 37.6 81.4 80.1 126.2 88.6 100.5 69.3 78.8 79.8 90.5 76.6 77.0 49.1 69.2 93.3 68.2 118.0 54.4 113.9 177.2 24.2 32.3 19.6 33.4 21.8 17.1 19.9 19.9 19.3 19.4 PPP1CB "PP-1B, PP1B, PP1beta" ENSG00000213639 "Protein phosphatase 1 catalytic subunit beta" P62140 2 28751640-28802940 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022558, HPA065425, CAB069426" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" 7700000 "Nucleoplasm, Plasma membrane" Cytosol "CAB022558: , CAB069426: , HPA065425: " "unprognostic (2.90e-1)" "unprognostic (5.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-1)" "prognostic unfavourable (6.52e-6)" "unprognostic (3.47e-2)" "unprognostic (2.44e-1)" "unprognostic (3.15e-2)" "unprognostic (1.54e-3)" "unprognostic (3.95e-1)" "unprognostic (1.68e-1)" "unprognostic (3.66e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-1)" "unprognostic (2.26e-2)" 28.5 22.6 30.0 20.5 37.6 29.5 32.4 19.1 29.8 51.1 39.3 21.1 30.7 24.4 58.0 31.8 86.0 37.0 33.3 67.1 27.8 27.9 32.0 20.0 35.3 22.3 27.4 24.4 39.7 21.9 48.9 28.7 42.3 22.0 46.4 27.7 25.2 36.5 38.6 99.6 25.1 30.0 100.8 27.5 25.2 31.4 25.5 21.4 28.1 27.5 32.9 25.3 82.1 50.5 15.6 25.4 41.5 42.7 23.5 28.3 17.9 36.4 23.0 80.2 24.8 27.5 25.6 46.7 19.6 22.4 19.1 18.9 20.4 21.6 29.2 24.7 20.3 22.6 22.8 26.2 22.8 46.3 11.8 22.0 28.2 22.0 59.9 24.9 10.4 19.6 37.3 20.6 43.2 23.1 20.0 29.0 25.0 18.3 26.4 21.6 26.3 18.2 26.0 71.1 22.2 62.2 44.1 22.0 27.2 30.5 33.9 26.6 16.4 14.0 27.6 25.6 28.2 18.3 23.6 20.7 32.5 59.8 27.2 26.9 18.9 22.5 24.8 32.1 16.8 37.8 21.3 15.6 25.5 19.6 25.4 13.4 22.7 25.5 41.5 23.5 42.7 19.6 28.3 17.9 30.0 37.6 19.1 29.8 27.8 27.9 27.4 24.4 22.0 21.4 PPP1CC "PP1C, PP1gamma" ENSG00000186298 "Protein phosphatase 1 catalytic subunit gamma" P36873 12 110719680-110742939 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022645 Uncertain 7600000 "CAB022645: " "unprognostic (1.51e-1)" "prognostic favourable (7.44e-4)" "unprognostic (4.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.29e-2)" "unprognostic (7.26e-2)" "prognostic unfavourable (2.75e-6)" "unprognostic (6.55e-2)" "unprognostic (4.11e-2)" "unprognostic (6.91e-2)" "unprognostic (4.96e-3)" "unprognostic (5.72e-2)" "unprognostic (2.92e-3)" "unprognostic (1.66e-2)" "unprognostic (1.71e-1)" "unprognostic (8.96e-2)" "unprognostic (1.18e-1)" 23.3 29.4 27.4 23.4 29.8 28.8 24.1 31.9 32.3 25.2 63.3 22.2 15.4 63.0 25.9 19.8 31.3 22.9 21.5 66.5 29.4 21.0 19.8 20.6 19.6 41.4 32.0 21.9 31.7 38.8 19.6 25.8 17.0 25.9 26.1 36.4 28.7 26.9 19.4 63.4 24.0 73.3 46.3 25.9 27.1 25.2 43.7 28.3 42.3 25.9 18.3 41.3 37.9 23.2 17.8 19.1 30.8 19.1 8.5 14.9 12.5 45.0 27.2 46.6 34.0 28.3 39.1 35.6 26.0 38.8 43.3 34.7 46.4 23.0 70.5 19.7 27.9 25.8 62.4 34.2 60.6 40.9 42.0 45.6 20.4 47.3 23.1 58.0 39.7 24.6 28.0 32.7 29.3 50.0 45.4 19.1 39.6 18.7 46.9 65.1 73.3 40.2 46.2 32.2 44.6 27.7 34.3 37.6 30.2 28.7 34.6 50.1 54.1 45.4 22.2 22.2 36.6 29.8 32.6 30.2 31.3 60.4 20.8 42.2 33.6 18.7 19.1 30.8 8.2 14.9 8.0 17.8 14.9 11.7 19.1 15.4 12.4 10.2 16.3 8.5 18.8 7.4 13.7 12.5 27.4 29.8 31.9 32.3 29.4 21.0 32.0 21.9 25.9 28.3 PPP2CA "PP2AC, PP2Calpha" ENSG00000113575 "Protein phosphatase 2 catalytic subunit alpha" P67775 5 134194334-134226142 "Enzymes, Predicted intracellular proteins" Meiosis "Hydrolase, Protein phosphatase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003848, HPA043236" Approved "CAB003848: AB_562203, HPA043236: " "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.60e-2)" "unprognostic (3.35e-3)" "unprognostic (1.26e-1)" "unprognostic (3.21e-2)" "prognostic unfavourable (7.33e-5)" "unprognostic (1.59e-3)" "unprognostic (1.57e-1)" "unprognostic (2.02e-1)" "unprognostic (1.34e-2)" "unprognostic (1.31e-1)" "unprognostic (5.24e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" 26.0 30.5 37.6 22.0 41.0 57.9 26.0 54.2 56.6 23.0 27.3 29.6 15.6 24.8 29.8 20.4 39.6 21.9 24.7 47.9 39.8 38.1 31.7 33.2 22.7 29.1 35.0 35.8 23.4 23.9 44.5 20.6 44.0 47.5 22.3 26.4 18.4 23.6 23.7 43.1 32.6 26.5 31.6 32.8 30.4 21.8 18.8 24.1 45.6 33.2 30.5 39.9 26.9 24.5 29.2 41.1 39.0 33.4 38.9 37.5 43.8 38.3 32.2 46.1 24.8 24.1 25.9 32.4 36.2 31.1 55.2 55.8 61.9 30.1 33.6 34.1 33.4 20.0 44.3 52.3 64.7 30.4 25.3 23.8 37.8 38.4 35.7 23.5 21.6 24.0 36.3 43.2 43.1 38.7 23.4 25.2 41.8 27.5 37.2 23.0 25.2 19.5 33.4 45.9 32.6 33.2 43.2 36.8 25.7 37.3 14.0 40.5 28.5 27.8 27.2 31.9 18.0 25.5 51.0 22.7 40.6 53.1 21.5 31.2 32.9 20.3 33.4 39.0 26.7 33.0 34.1 29.2 30.7 35.6 41.1 28.6 35.7 32.7 38.7 38.9 33.3 22.0 37.5 43.8 37.6 41.0 54.2 56.6 39.8 38.1 35.0 35.8 47.5 24.1 PPP2CB PP2Abeta ENSG00000104695 "Protein phosphatase 2 catalytic subunit beta" P62714 8 30774457-30814314 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018600, HPA043236" Approved Supported Nucleoplasm Nucleoplasm "CAB018600: AB_675841, HPA043236: " "unprognostic (9.77e-2)" "unprognostic (1.30e-1)" "unprognostic (2.51e-2)" "unprognostic (3.82e-1)" "unprognostic (6.70e-2)" "unprognostic (7.79e-2)" "unprognostic (1.13e-2)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.89e-2)" "prognostic favourable (5.82e-7)" "unprognostic (9.24e-2)" "unprognostic (2.04e-1)" "unprognostic (1.39e-1)" "unprognostic (2.65e-3)" 26.7 21.0 61.3 11.9 54.9 2.6 28.7 32.0 46.2 28.8 24.1 30.7 19.4 21.7 34.5 37.5 29.7 28.2 23.1 27.2 57.3 43.7 41.0 35.7 27.7 8.4 52.6 39.8 48.0 22.9 33.7 14.8 27.4 47.7 23.7 24.5 12.5 19.5 29.1 27.4 18.0 31.2 39.0 49.7 15.0 18.9 18.8 48.2 6.3 44.5 14.0 14.0 17.7 34.3 5.8 7.9 5.1 6.5 7.3 4.8 1.7 22.0 19.2 33.7 12.9 33.7 30.7 18.8 29.5 27.6 30.7 32.1 20.2 16.2 10.7 29.0 39.3 13.3 20.0 33.9 41.3 6.7 10.6 14.4 13.1 20.3 38.7 6.4 8.2 27.1 38.8 25.9 29.0 36.6 22.1 11.4 51.6 10.8 17.4 8.2 24.6 11.1 12.2 13.6 8.0 41.0 17.8 32.4 13.4 13.6 14.5 28.4 7.9 11.0 38.5 26.5 19.9 8.7 24.3 5.9 7.6 12.7 22.6 5.9 33.8 4.8 5.0 3.3 4.2 6.5 4.8 5.8 3.8 4.2 3.5 2.7 3.8 4.6 5.1 7.3 3.0 7.9 2.8 1.7 61.3 54.9 32.0 46.2 57.3 43.7 52.6 39.8 47.7 48.2 PPP3CA "CALN, CALNA, CNA1, PPP2B" ENSG00000138814 "Protein phosphatase 3 catalytic subunit alpha" Q08209 4 101023409-101348278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Craniosynostosis, Disease mutation, Dwarfism, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.8" "Low cell line specificity" "Detected in all" "Cancer enriched" "Detected in all" 7 "prostate cancer: 98.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012778, CAB018581" Enhanced Enhanced Nucleoplasm,Cytosol 35000 Nucleoplasm Cytosol "CAB018581: AB_2168324, HPA012778: AB_1855660" "unprognostic (6.66e-2)" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.36e-1)" "unprognostic (1.56e-1)" "unprognostic (7.81e-2)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "unprognostic (7.87e-2)" "unprognostic (3.49e-3)" "prognostic unfavourable (3.82e-4)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (5.12e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-2)" "unprognostic (5.74e-2)" 12.2 9.2 22.7 7.4 71.8 7.7 10.6 42.1 52.4 9.4 9.5 4.8 9.8 5.8 6.2 6.9 7.4 7.2 6.8 4.3 36.0 13.5 5.8 8.4 10.0 6.7 10.1 22.1 9.6 4.7 7.0 4.2 6.6 11.9 34.6 8.4 2.6 10.4 21.1 23.7 11.4 6.4 7.9 7.5 6.9 11.0 5.3 13.0 3.8 6.8 6.8 8.9 8.4 6.8 27.7 18.3 44.3 14.9 22.3 15.5 6.6 19.4 13.8 3.8 7.4 21.6 16.4 7.4 21.4 19.7 8.7 9.2 7.9 24.3 9.2 9.0 19.3 9.7 13.9 28.5 14.8 22.6 6.4 14.7 19.7 10.2 15.8 23.5 7.5 16.9 15.0 18.9 21.7 16.3 5.7 25.5 13.9 23.3 4.9 17.7 6.4 8.9 9.0 34.9 10.7 8.4 15.4 30.3 11.5 17.7 15.2 10.2 13.6 13.4 18.9 20.6 23.4 18.8 14.1 11.9 12.2 16.4 11.4 13.3 5.5 24.6 11.8 24.8 13.6 11.4 15.5 27.7 12.9 13.1 9.9 23.4 6.2 12.3 44.3 22.3 14.9 18.3 8.6 6.6 22.7 71.8 42.1 51.5 36.0 13.5 10.1 22.1 11.9 13.0 PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436428-73496024 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 133.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA008823" Uncertain Approved Mitochondria Mitochondria "HPA008233: AB_1855661, HPA008823: " "unprognostic (3.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.28e-2)" "prognostic unfavourable (9.59e-4)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "prognostic favourable (6.96e-5)" "unprognostic (4.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" 17.3 16.1 40.0 11.7 36.3 7.6 22.5 44.5 42.7 13.4 16.1 7.9 9.5 10.1 17.0 15.0 14.0 12.3 12.0 16.7 39.7 20.5 11.9 9.1 9.8 13.1 18.2 40.7 17.2 10.5 19.3 16.8 10.6 21.1 16.8 12.8 9.5 10.4 17.6 133.0 10.9 9.4 23.0 18.1 10.0 10.7 11.6 11.9 8.4 10.1 10.0 14.3 14.1 14.4 4.2 5.7 4.8 3.8 4.5 10.6 2.7 19.1 10.6 19.0 19.6 27.3 37.9 9.1 17.6 24.2 17.3 17.2 6.7 9.9 17.0 5.7 25.4 10.3 15.3 13.5 24.4 23.8 12.6 7.3 9.6 12.7 16.4 16.0 15.1 26.8 16.3 16.3 22.0 11.9 9.0 20.1 34.8 6.0 14.3 14.9 7.7 31.0 9.6 10.3 8.0 16.8 9.3 10.2 11.8 10.3 25.9 12.9 19.4 15.5 13.0 13.8 12.7 11.0 23.8 13.4 36.6 11.9 17.1 23.1 7.8 3.2 2.9 4.8 6.2 3.8 7.3 4.2 6.7 6.6 3.0 3.0 5.3 7.9 1.7 4.5 2.3 5.7 10.6 2.7 40.0 36.3 44.5 42.7 39.7 20.5 18.2 40.7 21.1 11.9 PPP3CC "CALNA3, PP2Bgamma" ENSG00000120910 "Protein phosphatase 3 catalytic subunit gamma" P48454 8 22440819-22541142 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023396, CAB024950" Approved Approved Vesicles Vesicles "CAB024950: , HPA023396: AB_1855663" "unprognostic (7.66e-3)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "unprognostic (7.71e-2)" "prognostic favourable (6.80e-5)" "unprognostic (9.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.84e-2)" "unprognostic (4.05e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (4.00e-1)" "unprognostic (2.78e-2)" "unprognostic (1.64e-2)" 18.0 8.3 6.9 13.7 8.1 15.2 21.1 11.9 12.0 10.3 10.2 10.9 3.7 6.1 13.4 7.8 11.6 9.0 10.7 27.5 7.6 7.3 8.9 8.2 16.5 22.3 7.7 4.9 10.1 9.9 13.7 15.1 12.7 9.9 11.1 7.1 20.7 15.5 6.0 52.4 9.1 9.8 13.5 7.9 14.1 9.5 41.6 6.9 6.8 11.5 13.2 20.0 14.7 11.0 15.5 4.0 6.6 2.9 11.9 16.0 3.9 5.4 4.0 3.6 4.4 9.6 11.9 5.3 7.6 13.5 11.4 12.6 2.3 3.4 20.8 9.4 11.8 3.9 8.3 7.6 14.6 11.9 4.4 4.4 4.6 6.7 13.0 3.2 7.4 7.2 10.6 7.6 7.9 9.8 8.7 27.8 12.7 2.5 7.5 5.2 2.6 5.6 24.5 8.5 6.9 10.6 5.2 2.5 6.0 5.7 3.4 7.8 2.3 5.4 10.5 17.7 3.8 26.8 5.9 13.9 16.7 21.8 9.4 4.2 11.7 3.4 1.6 6.6 11.4 2.0 8.7 15.5 12.9 16.0 3.2 13.9 12.4 10.1 0.4 11.9 2.9 4.0 10.1 3.9 6.9 8.1 11.9 12.0 7.6 7.3 7.7 4.9 9.9 6.9 PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085377 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: " "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (5.79e-3)" "unprognostic (3.28e-3)" "unprognostic (2.60e-3)" "unprognostic (3.82e-1)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (9.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" 24.7 26.6 13.5 26.1 14.1 26.7 18.6 16.0 15.9 19.2 28.4 14.5 20.5 22.5 19.2 28.4 39.1 17.7 31.9 28.5 12.6 12.1 28.9 52.3 27.4 25.3 12.5 12.8 22.5 26.3 23.9 16.2 51.6 11.9 18.3 17.4 18.8 22.0 14.9 26.0 26.1 38.8 15.9 11.9 36.2 22.6 39.0 9.5 59.7 27.1 26.5 37.9 22.2 21.1 19.5 30.3 57.3 28.2 12.4 23.6 12.0 30.3 34.1 22.8 31.8 21.6 18.2 35.4 27.1 30.2 35.7 39.7 30.0 39.7 23.7 34.9 31.9 24.8 28.2 33.6 21.1 29.6 50.5 16.1 21.2 66.2 32.8 22.6 30.5 26.4 29.8 32.5 20.6 41.4 31.3 21.7 27.2 87.6 39.3 41.2 43.3 18.2 44.0 23.7 41.2 33.7 31.3 22.2 32.8 13.3 40.2 23.1 37.0 38.5 26.3 20.9 21.9 16.8 20.8 37.2 40.9 27.7 29.8 29.1 25.2 21.4 26.9 57.3 18.3 28.2 13.1 17.0 19.2 20.6 30.3 19.5 17.2 15.2 56.9 12.4 24.5 23.5 23.6 12.0 13.5 14.1 16.0 15.9 12.6 12.1 12.5 12.8 11.9 9.5 PPP5C "PP5, PPP5" ENSG00000011485 "Protein phosphatase 5 catalytic subunit" P53041 19 46346994-46392981 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022641, HPA029065, HPA056933" Approved Supported Vesicles,Cytosol 47000 "Vesicles, Cytosol" "CAB022641: , HPA029065: AB_10610284, HPA056933: " "unprognostic (8.25e-2)" "unprognostic (7.90e-2)" "unprognostic (1.44e-1)" "unprognostic (6.30e-2)" "unprognostic (5.92e-2)" "unprognostic (2.62e-2)" "prognostic unfavourable (3.45e-6)" "unprognostic (1.29e-1)" "unprognostic (1.04e-2)" "unprognostic (8.25e-2)" "unprognostic (5.56e-2)" "unprognostic (2.20e-2)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.37e-1)" 18.9 24.7 23.0 18.1 28.8 13.4 15.9 25.2 50.8 20.4 21.1 19.4 15.2 18.0 23.0 15.2 20.1 27.8 20.5 48.2 20.8 23.9 22.6 22.1 17.4 19.3 21.9 29.8 16.7 21.5 26.3 23.9 17.3 34.5 19.5 17.5 19.7 21.0 21.4 40.8 16.4 15.3 23.5 16.2 21.7 20.6 19.0 15.3 15.6 18.1 20.5 16.1 17.1 18.1 10.6 11.1 1.9 14.1 14.0 19.8 8.9 19.5 36.8 22.0 16.6 16.6 17.8 10.2 24.3 19.8 29.6 26.7 26.4 15.6 30.0 13.3 17.7 16.1 28.9 28.7 8.9 20.8 39.2 25.0 27.0 18.7 18.5 33.8 17.5 16.2 13.6 20.8 15.5 25.4 24.0 15.5 16.8 21.2 18.9 63.4 16.6 20.1 28.2 19.0 24.0 17.7 26.8 31.3 23.0 20.4 26.0 8.7 16.3 21.6 21.1 13.0 21.6 9.6 25.4 12.5 28.7 36.0 13.9 28.4 21.6 0.0 6.8 1.9 19.8 12.1 12.7 10.6 9.2 15.3 11.1 8.7 8.9 12.0 0.1 14.0 14.1 7.9 9.3 8.9 23.0 28.8 25.2 50.8 20.8 23.9 21.9 29.8 34.5 15.3 PPP6C PP6 ENSG00000119414 "Protein phosphatase 6 catalytic subunit" O00743 9 125146573-125189939 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050940 Uncertain "HPA050940: " "unprognostic (6.45e-2)" "unprognostic (4.01e-3)" "unprognostic (7.12e-2)" "unprognostic (5.36e-2)" "unprognostic (2.78e-2)" "unprognostic (2.92e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (2.44e-1)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "prognostic favourable (4.50e-6)" "unprognostic (1.54e-2)" "unprognostic (3.51e-1)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" 21.7 20.1 20.1 15.7 24.5 24.8 21.2 20.8 26.2 17.0 19.1 25.9 15.1 13.9 15.6 17.2 21.2 14.0 12.9 15.3 19.8 16.6 22.8 17.8 16.3 21.5 20.1 16.1 17.5 27.7 21.3 17.3 17.6 17.8 14.5 21.8 16.8 26.9 14.6 50.5 19.3 17.3 16.3 22.6 19.4 16.5 22.8 23.7 34.1 22.2 20.5 24.0 13.8 15.6 17.3 14.8 32.2 19.5 13.9 23.3 13.8 14.3 10.5 19.2 18.1 20.6 17.3 19.4 15.3 16.6 22.6 18.9 16.8 15.3 20.7 11.9 20.5 29.4 25.9 16.6 26.3 18.5 12.5 17.0 16.5 14.9 16.9 29.6 23.6 14.2 22.8 18.5 17.8 21.0 19.9 24.1 24.3 21.4 27.9 18.7 17.8 19.6 22.8 29.0 27.7 19.2 14.5 19.9 19.7 27.3 22.0 17.7 34.0 18.7 20.4 13.9 13.3 27.0 20.2 26.6 48.0 27.5 18.7 19.4 22.6 27.2 13.2 21.4 14.7 17.4 18.0 17.3 18.9 16.6 14.8 13.3 18.9 17.5 32.2 13.9 19.5 10.7 23.3 13.8 20.1 24.5 20.8 26.2 19.8 16.6 20.1 16.1 17.8 23.7 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40071461-40097727 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 86.0;THP-1: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" 130000 "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavourable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 33.3 27.1 37.6 31.0 41.5 33.3 39.7 35.2 41.0 30.3 21.0 31.5 17.2 12.9 31.3 19.4 18.5 20.7 23.2 18.1 32.7 35.8 29.4 18.4 47.3 48.5 35.3 29.1 24.7 17.4 30.4 21.2 25.9 34.6 28.0 26.0 26.3 22.1 23.6 8.3 13.8 16.6 36.5 33.6 61.3 17.9 13.8 29.1 19.8 18.7 14.4 30.0 23.0 19.8 9.3 77.4 59.9 90.0 7.2 19.1 91.6 10.0 6.8 11.0 6.2 13.3 11.4 21.6 5.6 10.2 13.6 16.8 39.2 16.9 11.5 11.0 5.9 17.7 17.1 10.1 18.7 14.5 17.6 6.0 16.8 19.3 15.1 13.5 14.5 10.7 11.1 10.8 10.1 18.3 13.9 16.8 7.6 20.1 7.7 10.1 20.8 10.6 8.7 14.8 20.0 9.5 18.0 8.8 9.3 11.0 86.0 34.2 12.5 159.9 6.4 6.6 14.2 6.2 16.7 15.1 31.6 11.1 8.5 33.0 12.0 6.2 90.0 48.2 9.9 77.6 11.8 9.3 14.7 11.5 77.4 9.2 19.1 14.7 59.9 7.2 58.3 7.6 16.8 91.6 37.6 41.5 35.2 41.0 32.7 35.8 35.3 29.1 34.6 29.1 PPTC7 TA-PP2C ENSG00000196850 "PTC7 protein phosphatase homolog" Q8NI37 12 110533245-110583320 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 53.8" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039335, HPA040614" Approved Approved "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA039335: AB_10805474, HPA040614: AB_10795526" "unprognostic (2.44e-1)" "unprognostic (2.38e-2)" "unprognostic (1.11e-1)" "unprognostic (9.44e-2)" "unprognostic (2.38e-1)" "unprognostic (3.46e-2)" "unprognostic (2.14e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-2)" "prognostic unfavourable (1.43e-5)" "prognostic unfavourable (6.76e-4)" "unprognostic (1.09e-1)" "prognostic favourable (4.48e-5)" "unprognostic (5.34e-2)" "unprognostic (2.83e-1)" "unprognostic (5.01e-3)" "unprognostic (1.83e-1)" 10.4 15.3 6.5 10.3 9.6 26.2 10.3 8.3 12.9 9.7 11.8 5.7 4.9 7.5 9.3 4.6 12.6 7.8 8.8 35.3 9.0 9.0 12.6 11.9 13.1 10.9 10.4 6.8 8.9 7.5 13.0 12.7 6.9 15.3 7.7 9.8 8.0 12.9 8.2 53.8 13.4 11.7 13.1 7.4 9.4 8.4 8.2 6.5 16.1 8.0 15.5 13.1 12.4 12.4 2.1 1.4 6.1 1.7 1.7 2.4 0.6 12.0 6.9 5.9 6.2 14.8 13.1 8.5 5.6 7.4 6.1 6.2 7.8 4.8 21.2 5.8 5.4 11.8 11.9 12.9 12.4 15.4 9.8 18.8 7.4 8.4 14.1 20.7 15.5 11.2 21.3 8.6 25.5 11.6 13.9 6.1 9.9 3.1 18.3 17.8 8.4 12.9 15.3 8.0 12.9 25.4 13.6 9.6 7.5 10.5 14.6 12.3 6.9 11.1 13.2 5.6 6.0 17.1 9.3 17.6 19.4 23.7 9.5 11.5 11.0 0.1 1.7 1.3 2.3 1.5 2.4 1.3 1.9 1.8 1.3 2.1 2.2 1.9 6.1 1.7 1.1 1.4 1.3 0.6 6.5 9.6 8.3 12.9 9.0 9.0 10.4 6.8 15.3 6.5 PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82823502-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" 34000000 Vesicles "HPA017065: AB_1855676, HPA071115: " "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.33e-2)" "unprognostic (9.22e-2)" "unprognostic (1.42e-1)" "unprognostic (7.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.88e-2)" "prognostic favourable (2.65e-6)" "unprognostic (7.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" 32.6 45.9 25.0 21.5 22.2 13.1 69.5 19.4 23.8 38.8 17.9 17.9 27.6 11.0 30.7 35.5 32.2 24.6 25.6 66.3 25.8 18.9 52.4 52.5 38.1 95.1 27.0 14.8 27.8 23.4 30.6 19.3 59.8 34.9 25.1 18.4 25.1 38.1 34.5 10.3 26.2 15.7 32.8 45.0 25.1 16.8 17.4 17.7 9.8 27.9 24.2 31.7 39.4 30.1 13.1 50.0 31.2 27.9 12.1 6.2 14.7 7.5 8.2 12.6 25.4 97.9 35.9 14.8 16.0 28.6 15.4 22.5 20.3 15.5 10.8 23.4 23.2 11.9 11.5 10.5 18.0 9.6 8.3 7.7 11.4 12.6 18.3 6.9 28.2 26.2 8.3 16.0 15.2 50.8 8.3 15.2 15.7 3.4 1.0 24.7 7.3 7.7 5.6 21.9 12.9 21.5 13.8 5.3 11.5 21.9 12.7 9.0 15.2 9.5 13.2 18.1 18.1 15.6 7.8 14.3 24.4 9.6 7.4 8.4 9.3 15.5 26.4 17.4 5.3 27.9 6.1 9.9 5.3 5.8 50.0 13.1 4.4 6.2 31.2 12.1 21.2 8.9 5.0 14.7 25.0 22.2 19.4 23.8 25.8 18.9 27.0 14.8 34.9 17.7 PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477266-173488807 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" 180000000 "Plasma membrane, Cytosol" "CAB008663: AB_1620994, HPA006983: AB_1079595" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.96e-1)" "prognostic unfavourable (1.23e-5)" "unprognostic (5.71e-3)" "unprognostic (2.80e-2)" "unprognostic (5.27e-3)" "unprognostic (3.96e-3)" "unprognostic (3.19e-3)" "unprognostic (1.59e-1)" "prognostic unfavourable (9.51e-4)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-3)" 80.0 42.1 32.8 30.8 38.9 21.8 106.3 19.8 32.8 27.2 46.7 37.4 35.8 12.1 30.8 54.1 39.9 40.2 22.3 70.5 29.0 23.9 45.9 116.1 29.2 37.5 34.0 28.2 31.5 39.3 63.9 19.1 36.9 30.3 40.0 56.0 21.3 22.6 35.4 128.0 25.7 20.2 40.5 19.7 23.1 33.2 44.9 24.1 17.4 46.9 68.6 25.7 36.5 46.2 17.2 37.9 14.3 23.9 12.0 25.0 30.6 51.2 15.8 26.2 29.0 101.5 49.6 22.1 104.7 35.7 43.7 31.1 29.7 34.5 33.4 33.5 85.8 29.9 34.2 33.7 35.6 29.3 31.6 22.1 27.0 33.5 57.3 23.1 7.3 41.1 34.2 24.0 33.7 42.8 49.2 6.9 49.6 10.5 15.7 30.5 57.5 97.9 18.8 30.3 34.0 65.5 11.7 12.2 22.6 36.1 42.5 24.0 35.9 32.7 28.8 17.1 19.5 25.8 28.4 10.5 15.4 27.4 20.4 20.1 15.5 13.9 23.9 12.9 17.0 20.6 18.9 17.2 17.6 21.1 29.3 13.6 23.2 25.0 14.3 12.0 17.5 37.9 20.4 30.6 32.8 38.9 19.8 32.8 29.0 23.9 34.0 28.2 30.3 24.1 PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105277565-105403084 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol 1400000 Cytosol "CAB025414: , HPA031388: , HPA031389: , HPA031390: " "unprognostic (3.05e-2)" "unprognostic (9.09e-3)" "unprognostic (2.85e-2)" "unprognostic (5.46e-2)" "unprognostic (3.36e-1)" "prognostic unfavourable (3.33e-4)" "unprognostic (2.63e-3)" "unprognostic (2.39e-1)" "unprognostic (6.78e-2)" "unprognostic (5.81e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-3)" "unprognostic (2.74e-2)" "unprognostic (8.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" 13.0 14.2 10.1 22.2 10.1 10.4 36.2 10.9 24.9 11.9 27.2 5.2 11.2 20.2 13.2 10.9 16.4 10.5 15.0 19.0 8.8 7.1 8.9 14.6 23.9 31.4 8.3 15.4 13.6 18.8 16.1 11.1 15.4 9.7 9.4 33.0 8.9 14.9 11.5 58.0 24.2 19.0 15.3 8.5 11.9 14.0 20.1 8.8 17.4 10.2 18.5 13.3 18.2 21.0 8.3 15.3 7.1 18.7 16.6 16.3 11.2 10.8 13.3 14.2 15.9 33.6 19.9 14.0 14.6 13.7 19.3 20.5 16.9 6.9 13.9 14.4 17.1 16.9 20.9 42.8 22.0 21.0 20.4 18.7 11.2 19.2 13.0 18.8 13.7 18.5 26.1 13.9 35.8 18.0 31.8 24.9 23.3 17.6 12.5 19.1 13.7 13.3 19.4 24.5 9.1 14.4 25.9 18.6 26.5 12.8 21.5 10.2 9.2 30.2 18.1 8.9 12.3 11.1 17.9 7.3 4.8 18.2 15.7 20.5 27.6 4.8 13.6 7.1 16.0 15.4 15.6 8.3 13.7 16.3 15.3 6.8 12.9 15.2 0.7 16.6 18.7 6.5 12.0 11.2 10.1 10.1 10.9 24.9 8.8 7.1 8.3 15.4 9.7 8.8 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429246 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 137.5" "Cell line enriched" "Detected in some" 16 "Hep G2: 57.5" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 9 "plasmacytoid DC: 29.2" "Lineage enriched" "Detected in many" 9 "dendritic cells: 29.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005550, CAB016721, CAB016792" Supported "Secreted to blood" 6400000000 "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.2 4.2 137.5 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.4 29.2 3.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.5 0.0 0.3 0.0 3.6 0.0 0.1 0.0 0.0 0.0 0.0 2.7 57.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 29.2 0.0 0.1 0.4 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.4 0.0 PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753076 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1708 "pancreas: 3057.4" "Cell line enhanced" "Detected in some" "EFO-21: 3.5;HDLM-2: 1.7;RPMI-8226: 6.9;U-2 OS: 4.1;U-251 MG: 1.5;U-266/84: 2.5" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 1.7" "Low lineage specificity" "Detected in many" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" 26000000000 Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: , HPA063471: " "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavourable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favourable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favourable (4.91e-4)" "unprognostic (3.12e-1)" 0.4 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.6 3057.4 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.4 0.2 0.1 0.0 0.4 0.1 0.1 0.1 0.5 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 0.0 1.7 0.0 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 1.5 0.0 2.5 0.6 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 708 "pancreas: 6267.9" "Cell line enriched" "Detected in some" 5 "RPMI-8226: 37.2" "Cancer enriched" "Detected in many" 72 "pancreatic cancer: 3463.4" "Group enriched" "Detected in some" 6 "basophil: 5.6;T-reg: 5.1" "Group enriched" "Detected in many" 6 "granulocytes: 5.6;T-cells: 5.1" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" 27000000000 Vesicles "Endoplasmic reticulum" "HPA062452: , HPA063471: " "prognostic favourable (2.32e-4)" "unprognostic (3.80e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-3)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (3.50e-1)" "unprognostic (5.36e-3)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 6267.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 5.6 0.0 0.7 5.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.4 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.5 2.1 0.0 1.6 0.2 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.1 0.3 PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750466-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "pancreas: 984.9" "Cell line enriched" "Detected in some" 8 "PC-3: 121.9" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 82 "basophil: 39.0" "Lineage enriched" "Detected in single" 82 "granulocytes: 39.0" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" 490000000 Vesicles "Endoplasmic reticulum" "HPA062452: , HPA063471: " "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavourable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" 0.3 0.3 1.6 1.7 1.5 0.2 0.2 2.8 4.2 0.9 8.2 0.0 0.0 2.8 0.2 0.2 2.9 0.2 4.8 0.4 1.2 0.7 0.3 0.4 0.2 0.2 0.3 1.6 0.7 984.9 0.2 0.1 0.2 2.3 0.2 2.3 0.0 0.6 0.2 0.2 2.0 23.9 0.3 0.2 0.2 0.8 0.3 0.0 0.0 0.2 6.6 3.5 0.2 1.3 0.0 0.1 39.0 0.4 0.1 0.3 0.1 1.7 2.0 0.1 0.0 0.0 0.9 0.0 4.8 1.1 0.5 0.2 4.7 0.4 0.0 0.0 2.1 2.1 0.0 4.4 1.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.5 15.9 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 121.9 0.0 0.0 0.0 0.0 0.2 0.0 12.3 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 39.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 1.6 1.5 2.8 4.2 1.2 0.7 0.3 1.6 2.3 0.0 PRSS58 TRYX3 ENSG00000258223 "Serine protease 58" Q8IYP2 7 142252143-142258058 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 27.2" "Cell line enriched" "Detected in single" 22 "RH-30: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in male reproductive system" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840960-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "bone marrow: 167.3" "Cell line enriched" "Detected in some" 5 "THP-1: 148.0" "Cancer enhanced" "Detected in single" "stomach cancer: 1.0" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced "Secreted to blood" 120000 "CAB017558: AB_2172317, HPA005938: AB_1855764" "unprognostic (2.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.83e-3)" "unprognostic (4.20e-1)" "unprognostic (3.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.98e-3)" "unprognostic (3.67e-2)" "unprognostic (8.62e-6)" "unprognostic (5.31e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" 0.3 0.2 0.9 0.2 1.0 167.3 0.2 0.0 2.3 0.2 0.2 0.7 0.0 0.2 0.2 0.2 0.2 0.2 0.2 31.0 0.3 0.6 0.2 1.7 8.1 3.5 0.1 0.1 0.4 0.2 0.2 0.8 4.2 0.8 0.2 0.2 0.3 0.3 0.2 0.5 0.3 0.2 0.2 0.0 25.5 0.2 0.2 0.1 35.0 0.9 0.0 0.2 0.2 0.0 0.0 0.0 1.9 0.1 0.0 0.2 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 6.8 0.9 1.0 0.0 2.3 0.3 0.6 0.1 0.1 0.8 0.1 PRUNE1 "DRES-17, H-PRUNE, HTCD37, PRUNE" ENSG00000143363 "Prune exopolyphosphatase 1" Q86TP1 1 151008420-151035713 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 61.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028411 Uncertain Supported Cytosol 210000 Cytosol "HPA028411: AB_10603229" "unprognostic (6.24e-2)" "unprognostic (2.24e-1)" "unprognostic (4.17e-2)" "prognostic unfavourable (3.86e-4)" "unprognostic (6.91e-2)" "unprognostic (2.02e-1)" "unprognostic (2.12e-3)" "unprognostic (7.05e-2)" "unprognostic (4.08e-2)" "unprognostic (5.92e-2)" "unprognostic (1.73e-1)" "unprognostic (2.65e-1)" "prognostic unfavourable (3.48e-4)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-1)" 9.3 9.7 9.3 8.8 11.6 3.7 16.0 15.7 16.4 15.0 12.5 10.9 16.2 11.7 17.9 15.7 11.5 15.6 12.8 31.3 10.5 10.3 18.0 12.8 10.1 11.8 11.9 9.2 17.1 16.2 16.5 16.2 7.2 8.8 12.2 14.0 12.7 13.3 18.2 24.4 10.5 11.8 14.7 7.9 11.0 10.5 16.3 8.6 15.0 41.6 8.5 12.9 13.8 13.6 12.1 9.5 14.7 8.9 14.3 19.0 18.3 3.8 4.1 7.4 7.1 9.2 2.5 4.1 1.8 4.0 6.9 6.0 5.1 4.6 7.9 8.0 2.4 5.6 7.2 4.8 5.5 8.6 8.2 9.3 4.3 7.2 5.1 6.1 4.7 3.1 9.2 3.6 3.6 3.2 7.3 6.7 3.2 9.3 9.3 5.0 6.9 5.4 8.5 4.7 7.6 4.9 5.3 10.7 8.7 6.2 8.6 5.7 11.9 9.3 2.2 2.4 2.9 2.7 2.9 16.4 13.8 61.0 2.4 4.7 6.1 12.5 6.4 13.4 14.0 6.0 16.9 12.1 15.5 15.7 9.5 11.6 19.0 15.0 14.7 14.3 8.9 5.1 14.5 18.3 9.3 11.6 15.7 16.4 10.5 10.3 11.9 9.2 8.8 8.6 PSMA1 "HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30" ENSG00000129084 "Proteasome subunit alpha 1" P25786 11 14504874-14643635 "Enzymes, Predicted intracellular proteins" Immunity "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB033765, HPA037646, HPA043891" Supported Enhanced Nucleoplasm 27000000 Nucleoplasm "CAB033765: AB_2253026, HPA037646: AB_10670386, HPA043891: AB_2678718" "unprognostic (1.72e-2)" "unprognostic (4.97e-2)" "unprognostic (7.33e-2)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (6.66e-3)" "prognostic unfavourable (3.79e-5)" "unprognostic (3.28e-3)" "unprognostic (7.44e-2)" "unprognostic (3.43e-3)" "unprognostic (8.27e-3)" "unprognostic (8.77e-2)" "prognostic unfavourable (4.03e-11)" "unprognostic (1.93e-1)" "unprognostic (1.69e-1)" "unprognostic (4.66e-2)" "unprognostic (1.23e-2)" 46.6 46.3 33.7 36.0 40.2 45.7 39.0 28.3 42.7 33.4 35.5 23.1 37.4 37.3 42.1 43.1 43.7 33.0 32.2 55.4 31.7 34.1 47.8 61.0 38.8 42.3 32.0 32.4 34.0 35.6 28.2 39.4 55.2 36.9 35.6 42.4 32.9 34.9 37.1 86.6 35.3 42.7 39.0 26.7 45.8 37.3 31.6 25.9 53.0 45.5 62.8 42.2 41.5 31.7 24.2 55.4 20.9 42.3 30.5 35.7 45.2 66.1 46.8 39.2 46.9 39.1 39.4 32.7 39.1 51.5 59.7 49.1 40.5 83.6 57.9 43.4 41.3 49.9 44.7 48.5 56.6 56.2 66.4 36.1 31.1 47.8 51.4 59.8 47.2 38.2 28.9 32.4 67.8 58.4 67.6 48.8 53.0 43.9 54.4 45.0 32.7 69.8 36.9 58.1 35.9 51.9 46.9 32.4 20.4 41.7 46.8 34.9 27.9 36.6 46.1 39.1 36.8 68.4 47.8 21.4 57.2 51.8 57.8 47.7 49.9 20.9 42.3 11.0 24.3 31.1 32.3 24.2 28.3 27.2 55.4 20.6 25.7 25.0 9.4 30.5 29.4 31.3 35.7 45.2 33.7 40.2 28.3 42.7 31.7 34.1 32.0 32.4 36.9 25.9 PSMA2 "HC3, MU, PMSA2" ENSG00000106588 "Proteasome subunit alpha 2" P25787 7 42916857-42932223 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA008188 Uncertain 80000000 "HPA008188: AB_1855819" "unprognostic (9.40e-3)" "unprognostic (2.08e-2)" "unprognostic (8.21e-2)" "unprognostic (2.23e-2)" "unprognostic (4.13e-2)" "unprognostic (1.90e-1)" "prognostic unfavourable (1.29e-4)" "unprognostic (2.01e-2)" "unprognostic (9.25e-2)" "prognostic favourable (6.73e-5)" "unprognostic (1.77e-1)" "unprognostic (3.42e-1)" "unprognostic (1.62e-3)" "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (6.38e-2)" "unprognostic (4.24e-2)" 24.7 32.2 25.3 24.6 29.5 29.7 29.4 19.6 22.0 19.2 25.6 13.4 26.0 29.8 22.6 26.2 31.1 19.4 20.5 35.8 22.3 16.6 33.3 90.9 23.2 27.4 27.2 17.6 20.8 28.8 12.0 18.8 33.7 29.2 24.5 26.0 10.1 21.7 19.6 57.2 22.4 33.1 22.0 21.4 26.6 27.8 18.6 23.5 42.2 29.9 44.6 29.9 22.8 20.2 46.2 54.1 81.7 47.4 36.7 56.7 75.0 31.9 34.3 40.3 48.6 21.5 24.2 30.1 28.2 33.1 45.7 49.0 51.0 52.6 59.4 50.5 25.0 44.7 41.5 39.2 52.7 42.9 33.0 30.2 46.5 53.8 23.0 51.3 32.8 22.2 28.6 35.2 21.0 42.9 60.9 36.5 36.5 37.4 45.7 100.9 79.7 42.6 44.7 39.2 58.3 43.9 44.1 32.8 33.3 30.7 70.6 30.9 51.4 60.1 30.6 27.1 49.4 29.0 55.6 47.6 72.1 97.2 46.1 65.2 76.5 59.0 45.7 81.7 35.2 45.2 40.4 46.2 43.4 40.5 48.5 40.7 39.0 41.3 23.3 36.7 47.4 54.1 56.7 75.0 25.3 29.5 19.6 22.0 22.3 16.6 27.2 17.6 29.2 23.5 PSMA3 HC8 ENSG00000100567 "Proteasome subunit alpha 3" P25788 14 58244831-58272012 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000905 Approved 13000000 "HPA000905: AB_1079702" "unprognostic (3.60e-1)" "unprognostic (4.81e-3)" "unprognostic (1.17e-1)" "unprognostic (2.19e-2)" "unprognostic (4.91e-1)" "unprognostic (5.79e-2)" "unprognostic (1.97e-3)" "unprognostic (1.27e-1)" "unprognostic (7.92e-2)" "unprognostic (7.36e-3)" "unprognostic (1.65e-2)" "unprognostic (7.57e-2)" "unprognostic (1.83e-3)" "unprognostic (2.33e-2)" "unprognostic (6.47e-2)" "prognostic favourable (2.91e-4)" "unprognostic (2.16e-1)" 26.6 41.5 21.3 27.7 25.0 24.3 28.7 16.2 25.1 23.3 26.5 17.5 34.3 27.7 25.4 46.3 33.5 23.4 21.1 55.8 24.2 22.6 51.2 59.6 28.0 31.9 23.2 20.3 23.5 25.1 20.0 30.8 50.6 28.3 24.7 28.9 17.5 25.0 27.7 68.6 18.1 34.4 27.0 22.4 33.9 26.9 15.9 15.8 32.5 37.6 50.6 31.2 32.0 20.5 36.1 50.7 31.2 40.3 38.0 45.9 36.1 66.5 41.5 41.3 33.9 32.5 30.5 53.2 35.2 39.5 49.4 49.7 61.3 55.4 56.1 65.5 31.8 45.9 47.0 37.6 58.1 49.2 28.8 38.4 31.4 69.1 61.7 61.8 33.0 26.0 27.2 34.3 32.7 58.0 36.3 33.2 39.6 75.8 53.9 59.8 28.0 63.0 45.8 53.6 41.5 71.2 65.9 39.0 19.5 31.3 49.8 34.3 51.9 46.4 37.1 28.9 56.4 32.5 47.0 13.4 25.0 57.9 41.6 48.6 34.8 31.2 34.3 20.6 32.4 40.3 40.6 36.1 39.7 38.1 37.9 25.6 32.4 37.2 20.1 38.0 33.7 50.7 45.9 36.1 21.3 25.0 16.2 25.1 24.2 22.6 23.2 20.3 28.3 15.8 PSMA4 "HC9, HsT17706" ENSG00000041357 "Proteasome subunit alpha 4" P25789 15 78540405-78552419 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004973, HPA055466, HPA060613" Supported Supported Nucleoplasm,Vesicles,Cytosol 12000000 "Nucleoplasm, Cytosol" Vesicles "CAB004973: AB_425627, HPA055466: , HPA060613: " "unprognostic (1.80e-1)" "unprognostic (7.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (4.71e-2)" "unprognostic (5.35e-2)" "unprognostic (6.26e-3)" "unprognostic (1.09e-1)" "unprognostic (3.28e-2)" "unprognostic (2.08e-3)" "unprognostic (2.75e-3)" "unprognostic (1.26e-1)" "prognostic unfavourable (6.74e-10)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (3.78e-3)" "unprognostic (6.32e-3)" 41.2 38.8 24.9 36.7 25.8 33.4 33.0 25.3 37.5 32.4 38.0 17.9 23.7 39.4 35.3 32.5 49.9 27.1 24.4 37.7 29.8 27.6 55.7 76.3 37.4 45.1 25.5 26.9 31.2 24.4 20.2 25.9 55.4 33.8 35.3 41.3 19.1 26.0 25.0 60.3 26.3 49.1 36.6 28.1 45.5 31.5 36.5 21.4 61.6 42.6 75.0 44.8 41.3 28.3 29.4 61.9 31.4 75.6 37.7 40.0 61.4 40.1 58.2 50.4 44.4 31.8 30.1 39.5 37.8 30.4 46.6 50.0 60.5 58.7 87.7 55.9 34.8 55.0 101.6 41.0 45.1 35.9 70.8 73.6 43.6 48.7 51.6 74.8 45.5 24.3 25.7 39.2 39.1 50.2 78.9 34.4 38.0 57.8 50.4 70.2 47.4 34.2 43.9 66.7 29.4 47.2 70.4 44.5 32.5 60.6 44.3 46.1 40.9 61.6 39.9 34.8 46.5 38.3 64.3 31.5 74.2 82.7 32.6 112.5 38.3 18.8 47.4 31.4 27.8 75.6 28.5 29.4 29.2 29.0 61.9 22.9 23.3 28.3 21.7 37.7 69.7 35.3 40.0 61.4 24.9 25.8 25.3 37.5 29.8 27.6 25.5 26.9 33.8 21.4 PSMA5 ZETA ENSG00000143106 "Proteasome subunit alpha 5" P28066 1 109399031-109426427 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028392, HPA028398, HPA028441" Approved Supported Cytosol 22000000 Cytosol "HPA028392: AB_10600115, HPA028398: AB_10602310, HPA028441: AB_10602003" "unprognostic (3.82e-2)" "unprognostic (3.09e-3)" "prognostic favourable (1.45e-5)" "unprognostic (1.57e-1)" "unprognostic (2.71e-1)" "unprognostic (1.52e-2)" "prognostic unfavourable (2.28e-4)" "unprognostic (5.95e-2)" "unprognostic (1.71e-2)" "unprognostic (1.13e-3)" "unprognostic (4.20e-3)" "unprognostic (3.05e-1)" "unprognostic (1.07e-3)" "unprognostic (3.99e-2)" "unprognostic (2.34e-1)" "unprognostic (8.81e-3)" "unprognostic (1.05e-1)" 12.1 23.7 13.2 17.3 15.0 7.7 16.2 8.2 40.5 13.3 16.1 9.8 16.7 15.1 15.8 23.0 21.5 17.6 16.7 20.8 13.8 13.5 27.5 41.9 17.1 24.2 13.4 14.9 13.6 21.4 12.6 11.5 20.9 12.8 12.3 14.9 10.2 16.8 14.2 31.6 15.8 21.8 14.4 12.9 18.5 15.2 16.3 10.3 31.5 27.9 23.4 19.8 14.0 11.7 2.1 1.2 7.3 2.2 2.8 7.1 1.6 1.2 1.0 1.6 1.2 3.8 4.1 1.4 0.9 9.1 6.0 3.5 1.2 1.1 5.2 1.2 4.0 1.6 2.3 3.1 3.7 1.1 1.5 2.2 0.9 1.5 2.9 2.9 1.2 1.9 3.0 1.8 3.0 2.2 1.8 1.4 2.5 1.5 30.5 1.2 1.4 1.5 0.8 3.1 0.8 4.8 1.6 1.4 1.1 1.6 5.4 1.9 1.2 2.6 1.4 1.0 0.7 2.1 1.2 0.8 1.8 6.6 6.6 6.6 1.0 7.3 1.0 0.7 4.0 2.2 4.8 1.8 5.8 4.9 1.2 2.1 7.1 6.5 0.3 2.8 2.0 0.8 5.3 1.6 13.2 15.0 8.2 17.5 13.8 13.5 13.4 14.9 12.8 10.3 PSMA6 "IOTA, MGC22756, MGC2333, MGC23846, p27K, PROS27" ENSG00000100902 "Proteasome subunit alpha 6" P60900 14 35278633-35317493 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003049 Approved Supported Nucleoplasm 19000000 Nucleoplasm "HPA003049: AB_1079703" "unprognostic (9.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.90e-2)" "unprognostic (8.07e-2)" "unprognostic (3.42e-2)" "unprognostic (4.11e-3)" "unprognostic (7.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "prognostic favourable (3.27e-4)" "unprognostic (1.29e-3)" "unprognostic (2.63e-1)" "unprognostic (1.52e-2)" "unprognostic (2.05e-1)" "unprognostic (5.45e-2)" "unprognostic (3.49e-1)" "unprognostic (5.08e-2)" 33.8 42.7 26.7 31.4 38.8 37.1 38.7 24.2 35.0 28.0 35.8 19.4 24.5 32.2 31.0 30.2 37.9 24.7 20.3 54.2 30.5 27.6 47.3 49.0 37.3 36.4 30.1 36.8 31.1 36.7 14.2 35.8 61.2 31.8 22.5 38.6 18.1 27.3 25.5 94.6 31.8 39.5 27.3 25.2 35.7 28.9 67.5 26.5 86.2 26.0 37.2 38.1 28.8 24.5 37.9 68.5 41.4 65.1 49.9 54.8 104.8 58.9 43.6 32.7 33.2 27.0 28.8 65.4 30.9 37.8 46.8 42.6 40.6 42.8 39.5 59.5 30.0 42.3 38.1 35.3 56.1 39.7 20.8 31.0 31.8 121.4 30.6 64.5 29.0 21.9 29.4 32.7 41.7 39.6 33.1 27.7 37.8 62.6 98.6 55.1 31.2 49.7 147.1 33.2 31.6 40.0 75.8 34.8 29.4 34.5 50.8 32.5 60.8 42.7 32.9 30.2 29.8 30.7 34.2 29.5 64.6 72.2 24.5 40.9 34.0 32.8 65.1 41.4 46.3 59.4 46.2 37.9 44.8 47.1 66.8 29.9 35.9 43.0 23.5 49.9 56.6 68.5 54.8 104.8 26.7 38.8 24.2 35.0 30.5 27.6 30.1 36.8 31.8 26.5 PSMA7 "C6, HSPC, RC6-1, XAPC7" ENSG00000101182 "Proteasome subunit alpha 7" O14818 20 62136735-62143440 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046007, CAB046008, HPA047266" Approved 26000000 "CAB046007: AB_11128404, CAB046008: AB_2171861, HPA047266: " "unprognostic (1.49e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-1)" "unprognostic (6.57e-3)" "prognostic unfavourable (2.54e-5)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (5.06e-3)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (7.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.21e-2)" "unprognostic (6.31e-2)" "unprognostic (1.98e-2)" 45.1 40.2 26.5 35.0 28.0 56.1 53.1 23.8 30.7 23.2 34.2 21.1 25.4 32.1 33.3 26.6 36.6 26.4 27.3 64.7 26.3 25.7 36.0 63.6 32.8 36.0 28.4 27.0 28.0 48.0 17.1 21.5 27.9 25.0 27.7 27.6 20.7 25.7 27.7 130.5 26.2 33.1 36.9 24.7 34.8 29.7 16.1 22.6 37.2 33.0 53.4 36.8 36.1 44.0 92.3 112.0 124.4 111.2 64.3 114.6 153.5 56.2 69.9 43.1 44.8 39.8 30.6 39.8 44.2 36.2 108.9 46.0 183.0 53.0 46.8 103.1 44.3 67.6 40.2 78.4 54.3 29.3 31.0 104.9 70.5 92.3 49.4 44.6 61.6 32.7 64.1 56.2 50.0 53.9 46.0 44.8 47.2 57.7 71.5 71.3 36.2 101.1 49.9 81.3 50.7 41.6 53.1 58.1 35.7 66.5 82.6 71.1 49.6 67.6 43.8 96.9 79.9 50.9 65.7 32.1 49.3 55.1 67.6 34.3 56.3 98.4 111.2 124.4 93.3 109.7 79.2 92.3 93.7 92.0 102.8 83.7 74.7 77.5 94.4 64.3 109.7 112.0 114.6 153.5 26.5 28.0 23.8 30.7 26.3 25.7 28.4 27.0 25.0 22.6 PSMA8 "MGC26605, PSMA7L" ENSG00000154611 "Proteasome subunit alpha 8" Q8TAA3 18 26133852-26193355 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 36.5" "Group enriched" "Detected in some" 95 "Daudi: 23.4;U-266/70: 14.5;U-266/84: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "unprognostic (5.39e-3)" "unprognostic (7.45e-5)" "unprognostic (2.94e-1)" "unprognostic (3.04e-2)" "unprognostic (1.59e-1)" "unprognostic (2.72e-1)" "unprognostic (1.99e-1)" "unprognostic (8.30e-2)" "unprognostic (7.54e-4)" "unprognostic (4.80e-2)" "unprognostic (1.15e-1)" "unprognostic (2.56e-1)" 0.1 0.1 0.1 1.2 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.6 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 1.1 0.0 36.5 0.2 0.7 0.1 0.0 2.2 0.1 0.0 4.0 1.9 0.2 0.1 1.2 5.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 15.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.1 2.2 4.0 2.1 3.9 0.3 3.1 2.4 5.8 0.2 1.2 0.1 1.9 4.3 1.4 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.7 0.2 PSMB1 "HC5, PMSB1" ENSG00000008018 "Proteasome subunit beta 1" P20618 6 170535117-170553341 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029635, HPA029637, CAB033911" Enhanced Supported Nucleoplasm 14000000 Nucleoplasm "CAB033911: AB_2268890, HPA029635: AB_10599738, HPA029637: AB_10601793" "unprognostic (2.78e-2)" "unprognostic (3.10e-2)" "unprognostic (6.73e-2)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (5.41e-3)" "unprognostic (2.36e-2)" "unprognostic (3.32e-2)" "unprognostic (8.39e-2)" "unprognostic (4.28e-2)" "unprognostic (3.07e-1)" "unprognostic (1.09e-1)" "prognostic unfavourable (3.76e-6)" "unprognostic (3.63e-1)" "unprognostic (7.50e-2)" "unprognostic (1.45e-3)" "unprognostic (9.62e-2)" 60.8 59.3 38.5 40.4 53.7 53.2 55.0 31.4 46.4 40.5 48.6 37.9 49.9 45.1 56.8 90.6 51.7 49.8 43.1 71.9 40.9 40.1 56.4 93.2 46.9 66.7 40.8 41.1 43.7 67.3 35.4 48.4 80.6 48.4 40.6 52.7 43.8 43.6 50.0 109.3 56.1 46.0 59.7 44.9 51.4 46.9 47.1 38.1 47.1 47.9 75.2 60.4 50.1 42.0 71.0 98.1 51.9 81.9 71.6 79.3 104.1 42.5 40.0 57.1 73.6 51.1 40.2 60.8 40.8 60.0 68.0 69.6 87.5 36.8 62.3 53.2 54.5 43.1 63.3 64.8 71.0 63.4 71.2 53.2 40.6 109.7 60.0 62.4 47.5 45.8 39.9 65.6 42.6 58.0 105.0 53.5 62.0 114.6 46.7 87.1 52.1 55.1 45.2 45.3 79.0 70.5 25.6 57.1 46.6 39.2 60.9 31.2 41.7 90.4 44.1 27.7 44.5 67.3 75.3 45.8 60.6 77.4 64.7 70.7 59.4 40.1 81.9 51.9 53.2 75.8 62.1 71.0 62.2 57.7 98.1 53.4 59.2 57.2 47.5 71.6 67.6 55.8 79.3 104.1 38.5 53.7 31.4 46.4 40.9 40.1 40.8 41.1 48.4 38.1 PSMB10 "beta2i, LMP10, MECL1, MGC1665" ENSG00000205220 "Proteasome subunit beta 10" P40306 16 67934502-67937087 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 117.3" "Cell line enhanced" "Detected in many" "REH: 36.0;U-266/70: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "HPA030224, HPA030225, CAB034384" Enhanced Supported Vesicles,Cytosol 1400000 Cytosol Vesicles "CAB034384: AB_2171876, HPA030224: , HPA030225: AB_10603231" "unprognostic (1.18e-2)" "unprognostic (1.90e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-3)" "unprognostic (2.00e-1)" "unprognostic (1.85e-2)" "unprognostic (7.22e-2)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-1)" "unprognostic (8.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.32e-2)" "unprognostic (2.97e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-2)" "prognostic favourable (5.44e-4)" 11.5 13.0 9.1 24.9 11.8 23.9 11.4 4.0 7.8 8.0 21.6 5.6 8.5 42.4 9.3 9.5 10.6 12.4 16.6 12.0 6.9 4.9 16.9 17.2 19.5 38.3 9.5 5.6 8.7 61.5 0.9 6.9 11.2 8.5 13.5 6.3 5.8 27.9 11.6 6.9 7.0 35.6 7.7 6.5 49.7 23.8 2.5 7.8 39.2 13.1 10.4 20.5 13.2 8.4 50.8 75.2 100.0 98.1 69.1 68.8 117.3 5.9 5.3 0.4 0.8 0.4 3.5 21.0 2.0 8.5 6.9 9.8 2.7 29.1 21.6 3.7 2.7 8.7 0.1 1.9 0.5 9.6 0.5 7.7 1.8 3.0 12.0 14.3 23.6 5.3 1.2 3.0 0.0 4.0 0.7 8.3 1.9 7.4 28.1 14.7 0.3 2.0 36.0 2.2 29.5 4.7 10.4 0.3 0.4 6.7 11.8 2.6 2.4 31.0 6.7 4.4 1.2 1.9 2.3 40.3 7.2 14.4 10.9 18.7 9.5 57.1 89.4 67.1 68.8 98.1 50.2 50.8 54.0 57.3 74.6 49.1 45.3 50.1 100.0 69.1 71.4 75.2 60.8 117.3 9.1 11.8 4.0 7.8 6.9 4.9 9.5 5.6 8.5 7.8 PSMB11 beta5t ENSG00000222028 "Proteasome subunit beta 11" A5LHX3 14 23042167-23044276 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 32.7" "Cell line enriched" "Detected in single" 4 "PC-3: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 21 "T-cells: 2.1" "Region enriched" "Detected in single" 7 "olfactory region: 2.3" "Not detected" "Not detected" "HPA028967, HPA056970" Enhanced "HPA028967: AB_2732444, HPA056970: AB_2683293" "unprognostic (7.96e-2)" "unprognostic (2.77e-1)" 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 32.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 PSMB2 HC7-I ENSG00000126067 "Proteasome subunit beta 2" P49721 1 35599544-35641844 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026322, HPA026324" Approved Enhanced Nucleoplasm 15000000 Nucleoplasm "HPA026322: AB_1855821, HPA026324: AB_1855822" "unprognostic (3.54e-2)" "unprognostic (8.53e-2)" "unprognostic (1.63e-3)" "unprognostic (6.93e-2)" "unprognostic (6.41e-2)" "unprognostic (1.37e-1)" "prognostic unfavourable (3.49e-7)" "unprognostic (2.81e-2)" "unprognostic (5.23e-2)" "unprognostic (3.34e-3)" "unprognostic (7.87e-2)" "unprognostic (4.45e-1)" "prognostic unfavourable (2.80e-6)" "unprognostic (1.65e-1)" "unprognostic (2.83e-1)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" 26.5 30.5 29.4 28.0 35.1 37.2 25.3 20.1 50.9 23.2 26.1 35.9 15.4 27.5 27.8 25.0 30.4 26.5 20.7 23.8 30.6 33.4 27.9 63.8 24.6 30.4 30.6 24.8 22.7 24.6 22.0 21.8 37.5 32.6 23.1 27.8 22.8 23.0 24.9 54.7 28.2 27.0 28.7 32.5 29.3 22.8 23.5 21.5 42.8 22.7 29.1 34.0 23.9 22.4 24.6 30.2 19.4 35.3 25.1 28.1 25.4 40.6 25.5 27.8 19.0 14.8 17.8 35.2 19.3 22.7 39.8 32.5 30.2 48.9 40.6 45.3 22.7 25.3 35.8 32.0 33.5 33.1 33.2 36.8 27.9 29.5 26.7 38.6 21.7 19.4 20.3 47.5 23.1 31.2 43.9 23.2 25.6 18.7 50.2 28.9 37.2 27.1 31.1 28.4 28.6 27.6 22.0 24.7 18.2 22.1 20.9 29.8 15.4 17.6 21.5 19.9 23.5 18.8 45.5 20.0 32.2 41.1 29.5 40.7 34.5 17.4 27.0 19.4 23.1 33.0 23.4 24.6 23.1 24.2 29.7 19.3 16.7 20.9 9.7 25.1 35.3 30.2 28.1 25.4 29.4 35.1 20.1 50.9 30.6 33.4 30.6 24.8 32.6 21.5 PSMB3 "HC10-II, MGC4147" ENSG00000277791 "Proteasome subunit beta 3" P49720 17 38752736-38764231 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 99.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042775, HPA048147" Approved 28000000 "HPA042775: , HPA048147: " "unprognostic (1.86e-1)" "unprognostic (4.84e-3)" "unprognostic (1.44e-1)" "unprognostic (4.80e-2)" "unprognostic (6.68e-2)" "unprognostic (1.14e-3)" "unprognostic (5.46e-2)" "unprognostic (2.46e-2)" "unprognostic (2.02e-1)" "unprognostic (1.75e-2)" "unprognostic (3.65e-1)" "unprognostic (1.13e-1)" "prognostic unfavourable (1.71e-6)" "unprognostic (4.44e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-3)" "unprognostic (6.03e-2)" 13.3 9.6 5.2 9.9 8.6 13.3 10.3 3.0 13.9 8.5 11.8 7.5 6.4 9.2 5.6 15.3 14.7 10.3 9.8 15.6 4.4 21.6 36.8 11.6 13.0 8.4 7.1 9.6 11.3 7.3 5.7 17.2 8.5 10.8 12.0 9.1 8.5 10.0 22.2 10.0 14.1 11.0 4.7 17.5 7.2 8.5 7.0 23.3 16.7 12.2 15.6 10.2 5.6 32.7 55.0 99.0 56.5 29.1 43.1 63.7 27.7 52.2 21.7 33.5 24.1 19.0 27.7 18.3 31.1 64.4 56.8 62.4 36.1 31.9 33.0 27.3 47.9 35.8 35.4 39.9 41.7 62.8 20.5 30.3 64.7 12.0 32.8 31.6 19.8 21.9 48.4 16.4 34.7 33.0 36.3 31.0 36.3 51.0 51.1 29.3 39.0 28.9 43.9 50.0 37.5 28.4 26.8 17.7 23.5 17.8 22.7 41.0 38.2 18.3 16.9 31.2 35.9 46.7 23.7 40.3 41.3 33.5 32.5 29.6 41.1 56.5 47.4 30.3 49.7 27.9 32.7 28.5 27.6 55.0 28.1 23.0 24.8 99.0 29.1 39.9 53.2 43.1 63.7 PSMB4 "HN3, PROS26" ENSG00000159377 "Proteasome subunit beta 4" P28070 1 151399534-151401944 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006700 Approved 15000000 "HPA006700: AB_1079704" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (2.69e-1)" "unprognostic (2.52e-1)" "unprognostic (1.63e-1)" "unprognostic (5.74e-2)" "prognostic unfavourable (7.45e-4)" "unprognostic (2.27e-1)" "unprognostic (1.69e-1)" "unprognostic (4.37e-3)" "unprognostic (3.73e-1)" "unprognostic (3.77e-1)" "prognostic unfavourable (2.90e-10)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (3.82e-2)" "unprognostic (5.85e-2)" 45.7 64.5 47.4 40.4 49.5 40.2 56.3 39.6 84.0 44.4 44.3 28.5 58.8 41.2 53.5 65.3 55.7 51.2 37.8 66.6 47.0 50.7 57.3 71.9 43.6 81.1 49.2 61.0 52.4 87.0 40.0 45.4 50.9 48.4 42.6 47.5 37.8 46.7 56.1 68.7 45.7 39.7 66.4 55.1 46.6 43.4 31.8 36.3 51.1 46.8 63.3 62.2 58.6 37.7 68.5 106.5 58.6 81.4 72.5 89.0 78.3 51.2 53.8 45.8 54.9 51.9 49.5 63.0 30.2 66.1 88.3 62.0 71.9 69.3 46.7 91.8 50.6 51.5 46.4 56.9 50.5 65.1 47.0 32.3 40.3 53.8 56.1 44.9 44.4 54.0 54.4 83.0 34.1 61.6 52.1 91.4 62.2 137.3 53.9 52.9 117.2 69.7 51.7 33.5 82.4 72.2 41.9 50.9 60.5 35.2 76.9 101.2 69.5 71.2 39.0 38.8 41.3 41.2 66.4 91.1 104.3 90.0 57.3 40.0 81.6 54.6 81.4 49.5 63.9 75.2 75.9 68.5 74.9 72.5 96.4 60.8 65.8 68.0 58.6 72.5 56.9 106.5 89.0 78.3 47.4 49.5 39.6 84.0 47.0 50.7 49.2 61.0 48.4 36.3 PSMB5 "MB1, X" ENSG00000100804 "Proteasome subunit beta 5" P28074 14 23016543-23035230 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049518, HPA061796" Approved Supported Nucleoplasm,Centrosome 8200000 "Nucleoplasm, Centrosome" "HPA049518: , HPA061796: " "unprognostic (3.03e-1)" "unprognostic (1.99e-2)" "unprognostic (8.35e-2)" "unprognostic (6.13e-2)" "unprognostic (1.24e-1)" "prognostic unfavourable (2.85e-4)" "prognostic unfavourable (2.90e-5)" "unprognostic (2.55e-2)" "unprognostic (9.95e-2)" "prognostic favourable (1.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.19e-1)" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (1.95e-1)" "unprognostic (4.95e-2)" "prognostic unfavourable (4.73e-4)" 28.1 38.8 33.6 19.3 35.5 9.6 29.0 19.4 42.9 24.7 28.3 26.8 25.4 21.0 24.2 49.2 31.6 31.6 22.0 37.7 32.9 33.3 35.3 45.4 20.6 18.3 37.5 35.4 22.2 36.6 35.4 26.6 32.5 33.9 27.2 32.2 21.1 28.4 28.7 101.2 22.3 17.2 34.9 32.5 16.7 25.1 27.6 27.3 15.7 29.0 47.3 22.7 20.6 25.2 32.3 53.4 24.6 39.9 19.4 46.8 39.5 22.1 47.1 33.7 31.9 45.4 39.2 33.3 31.6 37.6 55.8 47.4 39.6 35.2 27.5 29.5 42.9 30.2 53.8 39.4 53.9 16.8 37.2 17.4 34.4 139.6 35.9 21.1 21.0 43.7 37.0 41.3 34.5 57.6 26.2 15.6 45.6 65.1 12.0 29.0 37.4 76.4 16.2 25.4 18.3 43.3 32.1 43.0 33.5 22.2 45.2 30.3 21.8 27.5 30.9 27.3 27.8 25.2 31.0 13.5 26.8 20.6 21.3 17.1 33.8 24.6 39.9 17.3 29.3 39.0 34.2 32.3 35.1 28.1 42.6 30.1 46.8 35.6 15.5 19.4 27.9 53.4 28.7 39.5 33.6 35.5 19.4 42.9 32.9 33.3 37.5 35.4 33.9 27.3 PSMB6 "DELTA, Y" ENSG00000142507 "Proteasome subunit beta 6" P28072 17 4796144-4798503 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023312, HPA063656" Supported Supported Nucleoplasm,Cytosol 2800000 Nucleoplasm Cytosol "HPA023312: AB_1855828, HPA063656: " "unprognostic (2.71e-1)" "unprognostic (1.86e-2)" "unprognostic (2.75e-1)" "unprognostic (3.32e-3)" "unprognostic (8.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-2)" "unprognostic (7.47e-2)" "prognostic unfavourable (5.93e-4)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (5.27e-2)" "unprognostic (5.66e-2)" 28.6 35.0 33.7 23.2 36.4 31.7 34.0 24.2 41.5 29.6 31.7 26.7 26.8 22.6 33.4 47.1 41.9 30.3 24.2 72.0 30.4 30.5 41.4 67.1 25.7 35.3 33.4 34.0 25.3 41.8 40.8 26.6 49.6 35.9 26.4 36.1 23.5 30.6 36.6 97.4 33.6 23.2 40.5 29.7 29.0 31.2 27.0 28.0 35.8 34.6 53.8 39.6 27.9 26.0 93.9 96.3 51.1 95.3 60.4 81.2 107.9 46.0 80.6 43.5 37.1 37.1 33.4 50.2 24.4 51.1 74.7 58.6 59.9 37.6 35.8 48.5 58.4 46.7 66.1 68.4 72.9 46.6 69.7 21.2 53.0 69.6 42.8 21.9 33.9 31.5 52.5 65.2 62.1 72.5 32.4 54.5 57.2 54.8 38.7 36.6 36.9 56.0 43.4 30.9 47.4 56.0 31.1 25.5 31.3 35.0 27.4 25.1 33.4 24.6 34.5 36.9 27.9 49.5 59.0 22.8 30.3 21.8 52.8 40.1 44.3 51.1 95.3 50.5 57.1 87.5 57.8 93.9 62.3 62.6 96.3 79.8 53.7 56.1 32.9 60.4 78.0 89.7 81.2 107.9 33.7 36.4 24.2 41.5 30.4 30.5 33.4 34.0 35.9 28.0 PSMB7 ENSG00000136930 "Proteasome subunit beta 7" Q99436 9 124353466-124415444 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052408, HPA054902" Supported Supported Nucleoplasm,Cytosol 2700000 Nucleoplasm Cytosol "HPA052408: , HPA054902: " "unprognostic (7.75e-2)" "unprognostic (1.83e-2)" "unprognostic (1.27e-1)" "unprognostic (3.64e-3)" "unprognostic (2.83e-1)" "unprognostic (1.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.24e-3)" "unprognostic (9.03e-2)" "unprognostic (3.60e-1)" "unprognostic (2.99e-1)" "unprognostic (1.78e-1)" "unprognostic (1.26e-2)" "unprognostic (1.67e-1)" "unprognostic (3.45e-1)" "unprognostic (1.93e-3)" "unprognostic (3.98e-2)" 36.9 56.9 51.0 32.8 55.1 53.4 41.9 33.7 52.7 26.6 33.3 34.0 27.9 32.5 33.6 52.1 41.9 32.6 29.2 59.6 44.5 41.3 53.7 87.1 27.0 33.6 43.6 46.9 32.7 67.1 38.5 24.1 53.2 47.3 28.8 37.1 31.1 48.2 26.9 76.7 48.7 32.2 31.4 39.9 28.6 33.1 50.3 36.5 48.2 32.7 67.7 39.5 32.3 30.8 53.4 67.9 45.2 62.7 53.6 66.2 69.0 51.9 63.5 43.5 52.5 30.7 36.7 62.7 50.6 69.8 73.4 50.7 83.4 50.8 59.3 40.9 47.3 74.4 54.1 53.6 67.4 57.0 46.7 37.1 101.0 69.2 69.5 73.6 37.1 43.9 47.3 76.4 76.6 61.5 75.7 42.2 56.6 90.4 52.8 49.5 64.3 90.9 46.8 64.9 69.3 51.9 34.0 51.3 41.8 48.1 61.7 74.9 71.1 32.4 48.7 47.5 38.3 60.6 75.7 45.8 128.3 59.8 79.4 45.4 66.7 40.4 61.7 45.2 41.8 62.7 45.0 53.4 48.1 46.1 67.9 47.5 46.3 44.9 27.3 53.6 58.4 57.8 66.2 69.0 51.0 55.1 33.7 52.7 44.5 41.3 43.6 46.9 47.3 36.5 PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome subunit beta 8" P28062 6 32840717-32844703 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" 3300000 Vesicles "Cytokinetic bridge" "HPA046995: AB_2679896, HPA050327: AB_2681088" "prognostic favourable (5.08e-4)" "unprognostic (4.22e-2)" "unprognostic (2.39e-2)" "prognostic favourable (7.16e-4)" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (7.78e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-3)" "unprognostic (7.11e-3)" 17.0 21.9 7.9 34.8 11.7 14.0 14.9 3.6 7.5 10.0 20.8 5.1 8.8 20.1 12.5 15.3 16.6 13.2 23.8 10.6 6.6 5.7 20.9 30.0 29.0 46.3 9.9 5.1 11.3 12.7 3.6 8.2 9.7 8.8 13.5 24.4 9.2 14.6 11.2 5.1 14.7 37.3 11.5 9.0 42.8 19.4 3.9 9.0 32.2 18.7 18.7 29.0 13.9 12.5 28.9 27.4 37.6 33.2 23.3 29.9 52.2 6.3 2.0 0.1 0.0 2.7 7.0 4.4 1.5 10.1 12.4 17.9 0.0 11.2 24.8 4.8 4.1 4.5 1.4 6.0 3.4 10.2 0.0 10.9 1.3 0.4 14.8 0.2 4.1 7.9 2.8 6.9 2.3 8.4 0.3 5.2 3.1 0.0 5.7 6.0 0.0 1.6 15.5 0.8 12.2 10.1 1.8 0.1 0.1 2.2 5.3 3.3 2.4 20.3 2.5 3.7 1.9 3.5 0.2 8.8 8.3 5.5 1.3 14.3 4.6 19.4 29.0 37.4 25.5 33.2 22.1 28.9 21.7 26.4 27.4 26.3 15.1 21.6 37.6 23.3 28.6 23.3 29.9 52.2 7.9 11.7 3.6 7.5 6.6 5.7 9.9 5.1 8.8 9.0 PSMB9 "beta1i, LMP2, PSMB6i, RING12" ENSG00000240065 "Proteasome subunit beta 9" P28065 6 32844136-32859585 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 69.1;lymphoid tissue: 54.9" "Cell line enhanced" "Detected in many" "Daudi: 29.1;REH: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB015180, HPA042818, HPA053280" Enhanced Supported Cytosol 420000 Cytosol "CAB015180: AB_2172368, HPA042818: , HPA053280: " "unprognostic (1.09e-2)" "unprognostic (1.68e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-3)" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (5.68e-2)" "unprognostic (6.67e-2)" "unprognostic (1.56e-2)" "unprognostic (6.50e-3)" "unprognostic (1.87e-3)" "unprognostic (1.84e-1)" "prognostic unfavourable (1.33e-4)" "unprognostic (2.65e-1)" "unprognostic (1.09e-1)" "unprognostic (4.96e-3)" "unprognostic (5.99e-2)" 13.3 9.7 5.0 30.0 7.9 10.7 11.6 1.6 5.3 7.6 16.5 6.0 3.4 15.7 8.8 7.1 10.8 7.4 10.8 8.9 5.1 4.7 12.2 12.2 17.7 32.7 7.3 3.7 9.2 5.4 1.2 4.5 5.5 6.3 12.5 5.8 7.7 9.0 3.5 6.2 7.6 36.1 5.7 9.8 54.9 11.2 3.0 6.7 35.4 14.4 9.3 35.2 15.9 8.8 31.8 17.2 69.1 30.5 23.4 31.1 45.7 0.0 1.4 0.0 0.1 1.1 2.9 2.0 0.2 3.2 4.2 9.7 0.0 9.1 29.1 0.4 2.6 5.9 0.4 6.2 0.5 16.4 0.0 17.7 0.5 1.1 15.7 3.1 1.3 1.3 0.2 2.6 0.4 1.5 0.7 5.4 1.4 0.4 13.4 4.1 0.0 0.9 21.5 0.0 6.9 2.8 0.5 0.0 0.0 2.7 1.7 1.9 2.3 6.5 1.5 4.5 0.4 8.5 2.5 10.1 15.3 9.3 4.6 11.8 3.8 21.9 22.4 39.3 28.7 30.5 23.8 31.8 23.3 27.5 17.2 23.4 17.5 22.9 69.1 23.4 29.4 12.7 31.1 45.7 5.0 7.9 1.6 5.3 5.1 4.7 7.3 3.7 6.3 6.7 PSPH PSP ENSG00000146733 "Phosphoserine phosphatase" P78330 7 56011051-56051604 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020376, HPA029515" Approved Approved Cytosol Cytosol "HPA020376: AB_1855867, HPA029515: AB_10601492" "prognostic unfavourable (2.30e-4)" "unprognostic (7.80e-2)" "unprognostic (1.55e-1)" "unprognostic (2.03e-1)" "unprognostic (1.07e-1)" "unprognostic (7.66e-3)" "prognostic unfavourable (2.75e-5)" "unprognostic (1.74e-1)" "unprognostic (2.13e-1)" "unprognostic (4.45e-2)" "prognostic favourable (3.77e-4)" "unprognostic (3.78e-2)" "unprognostic (5.74e-2)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.90e-3)" "unprognostic (9.05e-3)" 7.5 13.4 14.1 5.9 16.6 5.1 11.0 10.1 14.6 5.4 8.0 13.2 11.4 6.9 7.0 9.0 11.0 26.3 10.6 12.8 13.2 12.5 14.7 9.8 5.4 7.4 14.8 10.0 13.9 15.9 7.8 17.1 6.4 11.1 10.6 6.9 6.9 6.8 11.5 6.8 6.4 6.2 8.5 15.2 5.7 8.5 9.1 13.3 10.2 12.2 6.9 8.5 7.1 16.0 7.8 11.9 6.8 8.5 5.3 6.2 5.8 46.3 14.2 8.7 32.5 7.3 9.8 6.0 11.7 6.9 6.6 11.7 12.7 8.1 22.9 7.9 10.8 9.7 19.2 9.9 6.8 17.4 10.8 6.4 3.8 21.4 15.7 6.4 9.8 12.3 18.8 10.4 12.0 6.4 15.3 14.8 9.8 6.2 9.8 15.3 13.9 19.9 12.8 5.2 13.1 6.2 2.4 15.9 18.4 8.5 5.2 23.4 15.7 13.5 5.4 5.7 9.0 17.6 10.7 10.2 17.8 26.0 8.2 14.1 17.9 2.2 7.7 6.8 4.2 5.3 3.0 7.2 4.0 5.1 11.9 7.8 6.2 5.5 3.6 5.3 8.5 11.3 5.1 5.8 14.1 16.6 10.1 14.6 13.2 12.5 14.8 10.0 11.1 13.3 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863113-87971930 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 29.6" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Secreted - unknown location" Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: " "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavourable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 42.4 24.1 17.7 20.9 17.7 13.5 32.8 39.9 19.7 43.1 26.7 9.9 19.0 15.1 29.8 22.8 26.8 30.3 21.0 19.1 16.0 17.4 19.6 32.4 27.2 30.4 15.7 19.5 29.1 21.3 16.4 23.6 36.4 14.2 35.3 17.7 21.6 16.8 20.8 16.8 20.4 25.4 26.0 11.7 40.9 17.8 18.7 12.5 49.7 25.2 13.3 18.6 29.6 30.9 4.3 5.1 29.6 11.0 4.3 4.7 2.0 10.4 4.9 5.7 5.1 13.1 9.0 5.1 5.6 12.5 6.6 9.3 5.0 12.9 12.3 3.8 9.2 6.3 7.5 6.4 10.5 6.2 2.1 4.1 12.8 6.1 14.0 13.8 7.1 6.1 17.9 8.3 10.8 9.3 3.1 33.6 6.0 8.0 7.7 25.1 2.1 0.0 12.0 3.0 9.1 10.3 6.0 2.0 9.2 7.5 3.5 9.4 9.9 20.0 8.1 21.9 5.1 8.5 4.5 11.1 14.3 14.1 6.8 13.1 1.3 8.3 7.9 12.2 3.6 11.0 3.9 4.3 4.0 3.5 5.1 3.7 4.7 4.5 29.6 4.3 7.2 4.2 3.5 2.0 17.7 17.7 39.9 19.7 16.0 17.4 15.7 19.5 14.2 12.5 PTP4A1 "PRL-1, PRL1, PTPCAAX1" ENSG00000112245 "Protein tyrosine phosphatase type IVA, member 1" Q93096 6 63521748-63583587 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 135.1;skeletal muscle: 111.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003281 Approved "HPA003281: AB_1855903" "unprognostic (8.63e-2)" "prognostic unfavourable (5.53e-4)" "unprognostic (9.05e-2)" "unprognostic (7.96e-2)" "unprognostic (2.79e-2)" "unprognostic (2.71e-2)" "unprognostic (6.12e-2)" "unprognostic (1.96e-1)" "unprognostic (5.28e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.23e-2)" "unprognostic (1.07e-2)" "unprognostic (6.64e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (1.11e-2)" 13.9 42.3 11.3 10.5 14.0 54.3 10.8 7.1 17.0 17.5 30.2 18.9 8.0 17.9 13.1 13.5 16.1 12.3 16.7 10.0 12.0 14.8 14.2 135.1 25.0 9.0 16.1 13.8 24.1 87.4 5.0 12.8 19.8 16.3 17.7 31.2 13.6 20.1 10.0 111.2 17.2 18.3 35.7 24.2 7.1 15.5 19.8 13.3 6.4 11.4 19.9 9.3 31.0 12.6 14.6 18.2 46.9 20.6 15.8 20.1 14.4 18.9 23.6 29.7 28.7 20.3 18.9 59.5 33.4 22.3 12.2 17.0 19.8 11.2 16.2 14.5 19.7 9.4 20.2 42.0 19.6 17.4 13.6 10.1 65.9 89.9 40.2 31.0 16.5 22.9 81.5 26.3 70.5 18.8 23.1 31.5 33.8 25.7 14.8 13.9 12.3 12.8 19.9 12.3 12.8 27.2 22.5 11.2 20.6 73.0 16.0 32.9 15.4 27.6 18.7 30.7 33.7 24.2 32.9 26.3 22.5 29.9 16.4 16.6 36.0 34.6 19.8 15.2 13.7 20.6 20.1 14.6 15.0 14.6 18.2 12.4 14.8 14.2 46.9 15.8 14.2 9.1 18.1 14.4 11.3 14.0 7.1 17.0 12.0 14.8 16.1 13.8 16.3 13.3 PTP4A2 "HU-PP-1, OV-1, PRL-2, PRL2, ptp-IV1a, PTP4A, PTPCAAX2" ENSG00000184007 "Protein tyrosine phosphatase type IVA, member 2" Q12974 1 31906421-31944856 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003281, CAB011204" Uncertain 440000 "CAB011204: AB_532271, HPA003281: AB_1855903" "unprognostic (2.67e-2)" "unprognostic (6.36e-2)" "unprognostic (3.15e-3)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (6.20e-2)" "prognostic unfavourable (2.62e-5)" "unprognostic (6.90e-2)" "unprognostic (4.63e-2)" "unprognostic (5.12e-2)" "unprognostic (1.99e-2)" "unprognostic (1.03e-1)" "prognostic unfavourable (5.10e-11)" "unprognostic (1.16e-2)" "unprognostic (3.81e-1)" "unprognostic (2.89e-1)" "prognostic favourable (2.72e-5)" 51.6 22.4 41.1 39.6 57.3 74.6 48.8 12.0 34.6 26.3 37.1 68.9 24.9 31.9 23.4 20.8 25.3 23.9 31.6 64.8 50.6 31.4 26.7 36.3 34.6 44.0 56.3 29.5 34.6 28.5 17.1 19.2 25.8 40.9 28.6 36.9 21.1 28.0 27.5 82.8 16.5 29.1 32.7 58.5 40.9 31.3 44.6 48.7 110.5 48.0 20.0 47.2 49.0 40.3 14.7 14.8 50.0 44.6 18.2 29.0 18.2 41.5 24.2 23.8 44.3 47.7 51.1 16.2 40.8 57.0 33.5 34.9 21.2 60.3 73.9 32.2 55.4 16.9 24.2 23.7 62.3 66.4 13.8 51.3 43.0 22.1 51.2 41.6 52.0 46.9 19.8 47.3 46.7 34.0 65.9 30.3 43.0 20.2 133.2 20.4 31.8 35.4 23.2 39.9 30.7 22.4 76.9 23.3 16.8 43.5 28.4 46.2 80.9 23.1 35.1 39.5 33.4 58.9 45.0 31.6 49.2 37.7 38.3 34.2 38.3 50.0 17.2 27.4 25.4 32.6 20.3 14.7 22.6 29.0 14.8 11.3 14.5 24.9 18.0 18.2 44.6 10.7 17.8 18.2 41.1 57.3 12.0 34.6 50.6 31.4 56.3 29.5 40.9 48.7 PTP4A3 "PRL-3, PRL-R, PRL3" ENSG00000184489 "Protein tyrosine phosphatase type IVA, member 3" O75365 8 141391993-141432454 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 166.4" "Cell line enhanced" "Detected in some" "HDLM-2: 68.7;Karpas-707: 20.9;RPMI-8226: 21.5;U-266/84: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 30.3;non-classical monocyte: 27.8" "Group enriched" "Detected in many" 7 "granulocytes: 30.3;monocytes: 27.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003281 Uncertain "HPA003281: AB_1855903" "unprognostic (1.09e-1)" "unprognostic (3.70e-1)" "unprognostic (2.55e-2)" "unprognostic (1.10e-3)" "unprognostic (2.08e-1)" "unprognostic (6.18e-2)" "unprognostic (3.61e-2)" "unprognostic (2.27e-2)" "unprognostic (1.08e-1)" "unprognostic (2.50e-1)" "unprognostic (5.73e-3)" "unprognostic (2.33e-2)" "prognostic unfavourable (1.81e-5)" "unprognostic (2.25e-1)" "unprognostic (1.12e-2)" "unprognostic (2.28e-2)" "unprognostic (1.77e-1)" 5.9 2.4 2.8 3.9 6.5 1.7 4.1 3.9 10.9 5.5 6.2 2.6 2.5 3.4 7.6 5.4 5.5 6.1 3.0 48.0 2.7 3.0 5.1 1.7 5.5 7.9 2.8 5.0 4.8 13.6 2.4 22.0 4.1 4.6 7.2 2.0 15.7 8.2 3.8 166.4 3.4 3.3 7.6 1.5 5.6 9.9 3.5 0.6 1.7 3.3 15.9 5.1 5.5 3.3 2.8 4.3 30.3 27.8 0.8 3.5 2.5 0.1 0.4 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 2.0 0.0 6.4 0.1 0.0 0.1 0.0 0.0 68.7 0.5 4.9 0.0 1.0 0.5 0.0 0.2 0.0 0.2 0.0 0.0 0.1 2.7 20.9 0.0 5.2 0.5 0.1 1.3 0.3 11.8 0.0 21.5 0.0 0.1 8.8 2.1 0.4 0.0 1.8 1.0 0.3 0.1 0.0 1.2 0.0 0.0 6.5 22.8 0.2 0.0 2.0 0.2 0.4 1.6 6.6 1.6 14.8 1.1 2.8 3.5 1.6 1.2 0.8 3.4 1.9 30.3 0.8 27.8 4.3 2.5 2.5 2.8 6.5 3.9 10.9 2.7 3.0 2.8 5.0 4.6 0.6 PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase, mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040348, HPA043932" Approved Supported Mitochondria Mitochondria "HPA040348: , HPA043932: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavourable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 24.0 24.5 22.3 13.1 23.2 19.8 23.3 16.5 25.2 15.7 14.8 18.5 17.5 14.6 14.7 21.4 14.3 16.9 17.9 17.1 18.5 21.9 20.1 21.8 25.1 16.7 23.1 16.2 15.7 39.3 18.3 18.7 21.8 14.4 15.8 11.5 20.1 26.4 19.5 23.4 11.2 13.1 12.7 17.6 14.7 16.9 44.6 10.3 10.8 19.9 15.7 15.0 11.0 11.5 20.4 40.8 22.1 24.4 15.4 17.5 16.8 22.0 12.5 1.5 10.0 11.6 8.9 4.3 13.0 12.3 13.0 12.4 20.7 11.8 15.9 14.4 9.7 18.9 10.3 13.5 13.9 19.4 31.0 7.3 25.6 26.0 17.0 14.2 9.7 8.8 15.3 6.1 18.7 9.2 18.6 12.2 9.5 41.6 12.1 18.3 9.3 23.2 22.2 8.4 13.5 15.6 14.1 9.3 11.4 19.7 7.2 11.7 33.5 15.3 9.9 9.7 14.8 15.6 19.5 18.6 12.4 10.8 7.6 12.3 5.8 6.0 24.4 22.1 16.0 20.9 15.4 20.4 15.2 17.3 27.7 18.0 15.2 14.4 1.9 15.4 19.4 40.8 17.5 16.8 22.3 23.2 16.5 25.2 18.5 21.9 23.1 16.2 14.4 10.3 PTPN1 PTP1B ENSG00000196396 "Protein tyrosine phosphatase, non-receptor type 1" P18031 20 50510321-50585241 "Enzymes, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009329, HPA012542, CAB015217" Approved Enhanced "Endoplasmic reticulum" 11000 "Endoplasmic reticulum" "CAB009329: AB_2174944, CAB015217: , HPA012542: AB_1855915" "unprognostic (1.67e-1)" "unprognostic (7.78e-2)" "unprognostic (1.48e-1)" "unprognostic (1.05e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (2.98e-3)" "unprognostic (3.95e-2)" "unprognostic (2.40e-2)" "unprognostic (6.47e-3)" "unprognostic (5.87e-2)" "unprognostic (1.67e-1)" "unprognostic (1.66e-2)" "unprognostic (6.70e-2)" "unprognostic (2.99e-2)" "unprognostic (1.49e-1)" "unprognostic (2.58e-2)" 22.1 22.2 12.1 31.9 16.0 35.3 17.9 12.9 16.6 18.2 17.8 18.8 14.2 10.5 20.0 16.6 23.2 17.1 18.0 20.5 15.8 9.0 43.8 16.7 42.7 36.1 14.1 14.1 21.8 12.2 31.2 18.8 28.3 18.7 20.0 14.8 21.0 16.3 15.0 41.0 18.6 21.9 16.9 15.8 45.3 17.5 23.5 13.3 26.9 15.7 13.9 42.8 20.0 18.4 15.9 9.4 18.8 16.4 3.9 10.7 6.4 20.7 10.5 12.7 8.7 8.3 11.5 18.0 14.0 13.3 41.1 15.0 30.8 43.8 10.3 24.9 12.9 18.5 10.1 40.1 26.2 15.3 9.0 14.6 10.2 16.2 16.6 15.1 20.0 13.4 28.2 18.5 22.8 23.6 25.3 9.5 22.3 11.5 16.2 12.0 6.7 14.4 14.4 14.8 9.8 23.7 15.6 10.2 11.7 20.1 25.5 22.6 16.5 16.2 35.0 35.9 14.4 16.1 17.3 10.4 8.4 12.6 22.5 10.3 13.2 12.0 5.6 18.8 10.7 9.5 7.9 15.9 9.0 8.2 5.5 13.7 7.7 8.3 12.2 3.9 16.4 9.4 7.1 6.4 12.1 16.0 12.9 16.6 15.8 9.0 14.1 14.1 18.7 13.3 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase, non-receptor type 11" Q06124 12 112418351-112509913 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" 160000 Nucleoli "Nucleoplasm, Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 25.4 16.8 38.6 14.4 39.0 17.7 30.8 17.5 39.5 18.3 14.7 26.9 9.9 11.9 19.1 13.3 17.6 11.1 13.1 30.1 38.0 32.2 18.0 23.1 15.1 14.5 45.3 22.5 13.1 14.0 29.3 12.9 16.6 26.2 16.2 13.9 9.4 12.0 20.0 34.0 14.1 11.1 28.0 45.7 10.9 12.8 7.6 32.1 10.9 21.2 8.2 13.7 17.4 15.4 17.3 17.1 22.0 11.8 11.3 15.4 6.3 34.8 33.3 24.3 23.0 35.4 34.6 28.8 42.4 46.3 33.4 25.2 33.1 13.5 36.9 22.1 39.2 20.9 31.2 37.6 55.7 28.0 25.7 53.7 31.0 18.1 35.4 43.0 34.3 28.0 37.9 35.9 51.1 27.6 40.7 13.0 32.2 25.2 30.2 20.9 29.4 21.8 31.1 35.9 21.2 30.8 39.2 16.9 20.8 40.8 31.3 26.0 36.0 29.9 33.6 39.4 35.3 23.4 37.1 25.2 41.5 36.9 32.7 30.2 36.8 22.0 11.0 15.0 14.8 9.5 14.1 15.5 13.4 12.1 12.6 17.3 15.4 11.8 10.3 11.3 11.8 17.1 9.8 6.3 38.6 39.0 17.5 39.5 38.0 32.2 45.3 22.5 26.2 32.1 PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase, non-receptor type 12" Q05209 7 77537275-77640071 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" 1100000 "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavourable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavourable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavourable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavourable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" 29.6 15.1 14.3 20.5 19.6 29.7 25.1 15.7 22.7 20.0 28.9 8.1 13.8 8.8 20.7 9.6 22.0 18.1 19.8 45.6 17.3 12.6 16.9 14.8 34.7 17.4 15.3 13.4 19.0 10.7 12.4 19.8 36.0 18.6 14.1 13.8 9.9 12.8 17.1 17.6 17.6 14.6 23.0 24.0 25.0 14.4 13.9 17.7 9.7 16.7 11.9 12.9 23.2 61.2 2.5 3.9 9.9 4.9 12.8 3.8 2.8 17.5 10.8 25.7 13.1 18.1 18.9 13.8 18.4 23.4 14.5 20.7 5.3 27.6 2.1 5.9 21.5 12.6 8.6 18.4 29.3 5.1 4.8 11.0 10.9 21.7 17.7 6.2 7.4 15.4 20.6 31.5 40.8 30.6 13.2 3.1 46.2 12.0 0.8 17.4 20.7 12.4 3.7 20.6 1.1 24.9 9.5 3.2 17.1 22.6 20.7 17.9 10.0 23.0 22.2 31.4 19.0 11.4 34.6 3.2 1.7 5.4 18.5 16.3 54.4 3.7 4.2 6.6 3.6 2.9 1.4 2.5 1.2 2.7 3.9 1.1 0.6 3.8 9.9 12.8 4.9 0.3 1.5 2.8 14.3 19.6 15.7 22.7 17.3 12.6 15.3 13.4 18.6 17.7 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase, non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 3.0;MAIT T-cell: 2.3;memory CD4 T-cell: 2.2;non-classical monocyte: 4.9" "Group enriched" "Detected in many" 7 "monocytes: 4.9;T-cells: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 10.3 5.9 10.8 2.7 16.9 0.7 9.9 5.7 11.6 15.9 4.1 13.0 7.6 1.2 10.8 21.2 18.7 11.4 6.5 5.3 10.4 5.7 22.1 1.6 18.0 4.3 16.9 7.9 24.1 4.3 26.6 38.3 3.0 14.2 12.0 2.4 39.0 5.9 9.4 1.0 43.0 2.3 8.7 10.3 3.5 3.6 12.2 17.6 1.9 16.9 12.4 11.8 15.7 17.6 0.0 0.5 0.1 4.9 0.1 2.3 0.1 5.0 2.5 44.4 4.3 18.8 16.4 0.0 9.3 19.1 3.5 4.5 0.0 2.5 0.0 2.0 10.3 16.7 7.7 14.1 6.9 0.1 5.7 4.2 5.5 0.0 2.3 7.4 0.0 10.5 4.5 2.6 8.6 0.0 0.0 7.2 0.0 2.2 0.6 2.7 10.1 1.9 1.5 0.0 0.0 13.5 21.2 2.6 3.7 2.8 6.2 5.1 3.6 0.2 0.0 3.4 2.7 0.0 1.2 7.6 0.0 0.0 3.6 0.0 1.5 0.0 0.2 0.0 0.2 3.0 2.3 0.0 2.2 0.3 0.5 0.0 0.0 0.0 0.1 0.1 4.9 0.0 0.1 0.1 10.8 16.9 5.7 11.6 10.4 5.7 16.9 7.9 14.2 17.6 PTPN14 PEZ ENSG00000152104 "Protein tyrosine phosphatase, non-receptor type 14" Q15678 1 214348696-214552449 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011469, HPA053864, CAB069441" Uncertain Supported Nucleoplasm Nucleoplasm "CAB011469: AB_299202, CAB069441: , HPA053864: " "unprognostic (1.54e-1)" "unprognostic (8.19e-2)" "unprognostic (5.42e-5)" "unprognostic (1.42e-1)" "unprognostic (2.91e-1)" "unprognostic (5.97e-2)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (2.84e-1)" "unprognostic (1.31e-1)" "prognostic unfavourable (2.29e-4)" "unprognostic (7.43e-2)" "unprognostic (8.34e-3)" "prognostic unfavourable (5.16e-4)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "unprognostic (4.81e-3)" 13.6 10.0 3.0 6.5 2.4 0.2 15.0 0.8 3.7 13.6 8.5 2.6 11.0 1.0 15.4 8.0 8.6 9.2 9.7 7.0 3.5 1.9 11.2 2.0 12.2 6.6 2.4 1.3 11.8 5.0 6.3 4.0 13.2 4.9 10.6 2.9 7.2 9.2 23.4 21.6 18.8 3.5 9.4 4.3 5.3 5.7 8.3 2.4 1.4 8.1 6.9 3.7 12.4 17.7 1.0 0.5 1.9 0.4 1.0 0.6 0.1 8.7 3.9 3.2 4.6 5.6 9.5 9.4 9.9 9.3 7.6 6.4 7.9 4.6 0.0 11.1 23.1 7.8 4.3 11.1 13.1 0.1 3.3 0.8 11.1 1.4 10.1 0.1 0.4 7.1 11.6 13.2 21.3 14.7 0.0 0.1 18.4 0.9 0.1 0.1 7.0 4.2 0.1 16.0 0.0 13.7 4.4 0.0 0.7 12.3 8.1 5.0 8.0 0.3 26.2 17.9 7.0 6.4 14.1 0.5 0.0 0.0 9.6 0.1 14.9 1.3 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.4 0.1 1.0 0.5 0.6 1.9 1.0 0.4 0.5 0.6 0.1 3.0 2.4 0.8 3.7 3.5 1.9 2.4 1.3 4.9 2.4 PTPN18 BDP1 ENSG00000072135 "Protein tyrosine phosphatase, non-receptor type 18" Q99952 2 130356007-130375409 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012174, HPA053367" Uncertain Approved "Intermediate filaments" 550000 "Intermediate filaments" "CAB012174: AB_2173224, HPA053367: " "unprognostic (3.11e-3)" "unprognostic (2.89e-3)" "unprognostic (1.67e-3)" "unprognostic (1.73e-3)" "unprognostic (5.81e-3)" "unprognostic (3.08e-3)" "unprognostic (2.49e-2)" "unprognostic (1.28e-2)" "unprognostic (4.65e-1)" "unprognostic (2.10e-2)" "unprognostic (7.33e-2)" "unprognostic (5.65e-2)" "unprognostic (4.52e-2)" "unprognostic (1.00e-2)" "unprognostic (3.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.85e-3)" 12.8 7.1 11.0 16.7 13.5 18.9 22.3 26.8 13.7 15.3 22.8 6.6 25.7 16.6 9.3 11.0 11.3 13.3 21.3 7.5 9.8 8.5 13.9 19.2 16.9 29.2 8.4 9.5 7.8 28.9 6.4 11.0 9.4 6.9 17.8 19.3 7.9 18.5 24.0 11.0 6.9 28.8 10.5 9.1 37.7 16.0 3.3 9.1 1.6 13.0 7.1 35.5 11.0 10.7 7.6 7.4 6.2 17.1 2.8 6.6 10.2 5.8 3.9 1.5 7.9 9.8 6.8 16.3 3.0 2.7 3.9 4.3 7.8 8.9 21.8 3.0 7.2 6.7 6.9 6.7 3.8 9.9 3.8 7.9 4.7 9.1 5.1 7.7 21.4 8.0 5.5 4.2 5.9 7.3 7.3 16.6 7.4 11.3 1.4 13.3 1.6 4.2 13.3 4.5 29.5 7.7 3.6 10.1 2.6 5.3 18.9 8.6 6.5 11.3 6.8 5.5 6.3 3.0 2.7 2.6 0.7 20.9 8.5 7.0 6.0 6.2 7.8 6.1 6.6 10.8 4.1 7.6 4.4 6.3 6.7 4.5 2.7 5.4 4.9 2.8 17.1 7.4 5.6 10.2 11.0 13.5 26.8 13.7 9.8 8.5 8.4 9.5 6.9 9.1 PTPN2 "PTPT, TC-PTP, TCELLPTP, TCPTP" ENSG00000175354 "Protein tyrosine phosphatase, non-receptor type 2" P17706 18 12785478-12929643 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015004, HPA046176" Enhanced Supported Nucleoplasm Nucleoplasm "HPA015004: AB_2669131, HPA046176: AB_2679569" "unprognostic (5.83e-3)" "unprognostic (8.50e-2)" "unprognostic (5.85e-2)" "unprognostic (7.21e-3)" "unprognostic (8.94e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-1)" "unprognostic (2.37e-3)" "prognostic favourable (1.37e-4)" "unprognostic (1.06e-2)" "unprognostic (1.75e-2)" "prognostic unfavourable (1.20e-8)" "unprognostic (3.19e-1)" "unprognostic (6.84e-3)" "unprognostic (2.17e-1)" "unprognostic (4.61e-3)" 16.7 12.5 12.6 27.0 14.3 33.7 19.9 32.6 19.2 14.7 15.0 7.8 17.8 12.9 12.2 14.9 17.0 13.7 15.7 12.8 13.1 6.8 13.6 20.5 21.6 30.3 15.3 10.3 22.1 28.2 10.4 27.2 13.3 13.8 14.4 17.1 7.9 26.3 16.0 13.1 16.0 15.3 11.8 24.7 24.2 13.1 9.4 15.9 61.3 14.7 11.7 28.9 16.5 15.8 29.1 32.8 19.9 28.0 31.7 29.2 19.6 13.0 7.9 9.3 3.1 10.6 19.2 9.0 8.7 19.4 18.7 16.8 17.2 18.9 20.5 14.7 9.0 7.8 15.1 23.9 24.7 7.9 9.1 14.5 6.9 17.9 14.7 33.9 13.8 16.1 22.7 17.0 33.8 9.5 14.0 27.9 15.0 14.9 33.8 28.0 11.1 9.3 11.4 14.6 23.2 15.7 20.9 16.7 8.7 17.7 10.4 15.1 8.7 19.5 7.2 23.8 23.0 17.7 18.8 8.9 8.9 29.6 11.2 18.7 9.9 11.5 28.0 19.9 21.0 24.6 28.2 29.1 24.8 23.1 32.8 20.3 18.3 20.0 10.2 31.7 22.8 28.0 29.2 19.6 12.6 14.3 32.6 19.2 13.1 6.8 15.3 10.3 13.8 15.9 PTPN20 "bA142I17.1, bA42B19.1, CT126, DKFZP566K0524, PTPN20A, PTPN20B" ENSG00000204179 "Protein tyrosine phosphatase, non-receptor type 20" Q4JDL3 10 46911396-47002488 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.2" "Cell line enriched" "Detected in some" 5 "HDLM-2: 32.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA043337, HPA046896, HPA048310, HPA069148" Enhanced Supported "Centriolar satellite" "Centriolar satellite" "HPA043337: , HPA046896: , HPA048310: , HPA069148: " "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.04e-2)" "unprognostic (2.82e-3)" "unprognostic (6.78e-2)" "unprognostic (1.85e-1)" "unprognostic (8.44e-2)" "unprognostic (1.92e-1)" "unprognostic (1.53e-1)" "unprognostic (2.22e-2)" "unprognostic (2.83e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-2)" "unprognostic (1.75e-1)" "unprognostic (8.34e-2)" 1.2 9.7 1.0 1.9 3.1 0.0 3.4 3.4 5.4 0.8 1.3 1.0 5.0 1.1 1.4 0.4 3.4 1.0 0.5 8.8 1.4 3.4 4.3 0.6 0.6 0.2 2.4 0.8 1.6 3.9 0.0 2.3 0.3 11.7 1.1 1.5 1.2 7.8 3.2 11.0 5.6 1.0 0.6 1.2 1.0 1.0 13.2 0.0 0.2 1.9 1.7 0.5 1.0 1.0 2.8 2.2 0.0 0.0 2.3 3.1 0.7 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 1.9 2.4 0.0 0.0 0.0 32.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.5 0.8 5.9 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 4.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 2.8 1.7 0.4 1.1 0.6 2.2 3.1 0.0 2.3 0.0 2.2 1.3 0.7 1.0 3.1 3.4 5.4 1.4 3.4 2.4 0.8 11.7 0.0 PTPN21 "PTPD1, PTPRL10" ENSG00000070778 "Protein tyrosine phosphatase, non-receptor type 21" Q16825 14 88465778-88554733 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB011468, HPA073999" Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" "Plasma membrane, Cytosol" "Nucleoplasm, Golgi apparatus, Centriolar satellite" "CAB011468: AB_442979, HPA073999: " "unprognostic (2.18e-1)" "unprognostic (4.21e-2)" "unprognostic (7.60e-2)" "unprognostic (3.09e-2)" "unprognostic (4.60e-2)" "unprognostic (5.71e-2)" "unprognostic (6.55e-2)" "unprognostic (5.19e-3)" "unprognostic (6.62e-2)" "unprognostic (1.02e-2)" "unprognostic (8.71e-3)" "unprognostic (3.04e-3)" "prognostic favourable (3.16e-9)" "unprognostic (6.52e-2)" "unprognostic (2.69e-1)" "unprognostic (2.56e-1)" "unprognostic (7.67e-2)" 10.5 4.7 5.3 8.6 7.3 0.0 13.2 4.4 5.8 10.7 8.7 10.7 7.4 4.9 10.6 10.7 8.9 8.3 12.7 17.4 7.4 4.2 8.1 6.0 15.3 1.6 6.6 4.2 15.8 7.8 10.6 3.9 15.6 6.4 11.9 6.5 12.6 6.5 10.5 8.8 24.2 10.5 15.7 7.3 3.7 7.4 15.2 6.5 0.8 16.0 8.4 3.1 12.0 26.1 0.8 0.0 0.0 0.1 0.0 0.1 0.0 3.5 2.9 7.6 2.9 8.1 7.0 7.8 9.6 7.4 5.7 7.9 5.1 6.5 0.0 2.3 12.2 3.4 1.1 3.4 8.4 0.2 1.7 0.0 3.1 2.1 9.0 0.0 0.1 4.7 6.7 4.8 5.7 4.6 1.1 0.1 14.6 2.9 0.0 0.1 2.2 5.6 0.0 22.7 0.0 4.9 2.6 0.5 8.8 5.5 13.8 3.2 6.8 1.4 9.0 10.6 8.4 4.3 6.5 0.3 1.1 0.0 3.9 0.1 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.3 4.4 5.8 7.4 4.2 6.6 4.2 6.4 6.5 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase, non-receptor type 22" Q9Y2R2 1 113813811-113871759 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease mutation, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.6;lymphoid tissue: 46.0" "Cell line enhanced" "Detected in some" "Daudi: 32.9;HL-60: 13.0;U-266/70: 14.2;U-698: 17.6;U-937: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Region enriched" "Detected in single" 10 "cerebellum: 5.9" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 4.2 1.4 0.5 17.1 0.8 23.6 1.9 1.0 0.5 2.4 3.3 0.3 1.0 4.1 2.0 2.2 2.0 1.7 3.2 2.5 0.6 0.7 3.4 1.8 9.0 14.9 0.7 0.4 1.5 2.4 0.0 0.9 0.9 1.0 1.7 2.8 1.3 2.7 3.0 0.6 1.0 9.9 0.9 2.1 19.0 3.1 1.1 0.4 46.0 1.5 2.4 12.8 4.8 1.7 7.2 6.2 17.2 3.5 7.5 14.9 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.0 0.3 0.0 0.2 32.9 0.0 0.1 0.0 0.0 0.0 0.2 3.1 0.0 4.6 0.0 0.0 0.1 13.0 10.3 2.9 0.0 1.4 0.1 5.1 0.0 7.5 5.0 0.1 9.2 7.4 0.0 0.0 0.5 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 2.3 7.8 0.1 0.1 0.2 14.2 3.0 17.6 5.4 13.4 0.0 10.2 3.5 17.2 12.8 0.9 14.9 7.2 6.5 10.1 6.2 4.7 3.9 9.4 1.7 7.5 0.4 3.7 10.0 4.6 0.5 0.8 1.0 0.5 0.6 0.7 0.7 0.4 1.0 0.4 PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase, non-receptor type 23" Q9H3S7 3 47381011-47413441 "Enzymes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies" "Nuclear bodies" Nucleoplasm "HPA016845: AB_1855926" "unprognostic (1.17e-3)" "unprognostic (8.68e-2)" "unprognostic (2.56e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (1.07e-3)" "unprognostic (2.07e-2)" "unprognostic (9.55e-2)" "unprognostic (7.12e-2)" "unprognostic (5.67e-2)" "unprognostic (4.34e-2)" "prognostic favourable (1.82e-4)" "unprognostic (3.05e-2)" "unprognostic (4.40e-1)" "unprognostic (9.53e-2)" "unprognostic (4.68e-2)" 15.9 18.5 23.1 17.4 22.3 19.2 21.6 22.8 25.0 18.1 12.5 21.4 14.6 20.7 20.0 15.1 17.2 17.2 12.8 13.2 17.9 11.7 16.4 13.0 16.8 17.8 24.6 23.7 23.4 19.4 53.4 29.9 17.1 20.5 16.9 10.4 15.2 20.8 19.0 25.7 25.9 16.0 16.0 20.3 19.2 17.9 17.8 22.7 9.7 24.8 9.7 11.1 17.7 18.1 1.4 1.1 3.7 1.2 0.9 1.5 0.8 13.1 18.7 10.4 13.5 13.6 10.5 10.0 11.9 11.9 11.2 9.5 15.8 13.0 9.4 11.0 13.5 11.8 9.0 13.0 5.4 8.6 9.6 12.8 13.7 14.6 15.0 7.5 17.5 14.0 13.3 14.5 14.9 13.7 9.6 12.9 11.9 18.3 7.1 6.3 11.1 13.1 4.4 5.1 11.2 8.4 25.3 5.6 13.1 10.5 22.5 8.7 12.8 7.3 13.8 17.2 14.5 23.8 16.9 18.4 12.1 5.4 18.6 7.1 12.1 3.7 1.2 0.0 0.8 0.5 0.6 1.4 0.6 1.3 0.4 0.7 0.6 0.8 1.4 0.9 0.5 1.1 1.5 0.8 23.1 22.3 22.8 25.0 17.9 11.7 24.6 23.7 20.5 22.7 PTPN3 PTPH1 ENSG00000070159 "Protein tyrosine phosphatase, non-receptor type 3" P26045 9 109375466-109498313 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 38.1" "Cell line enhanced" "Detected in many" "HaCaT: 15.4;RPTEC TERT1: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038343, HPA046728" Approved "HPA038343: AB_10671741, HPA046728: " "prognostic unfavourable (6.71e-4)" "unprognostic (3.48e-1)" "unprognostic (3.64e-2)" "prognostic favourable (1.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (3.71e-2)" "unprognostic (5.38e-2)" "unprognostic (6.37e-2)" "unprognostic (3.57e-2)" "prognostic favourable (1.22e-15)" "unprognostic (1.64e-2)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (8.21e-2)" 2.7 1.9 3.4 4.8 5.0 0.0 4.8 2.1 11.1 4.4 9.4 2.0 10.7 7.6 3.2 13.4 10.3 6.4 6.3 12.1 3.1 2.8 28.8 21.1 4.9 0.5 1.2 3.9 1.5 17.0 10.6 4.9 14.5 4.5 4.7 6.5 3.8 13.1 13.6 38.1 18.8 18.8 0.8 0.9 0.9 5.9 2.1 0.0 1.1 9.4 7.2 9.5 4.1 5.5 0.6 0.3 2.8 0.6 0.3 0.3 0.1 6.4 8.0 0.3 2.1 0.0 0.0 12.7 1.4 0.0 1.7 1.9 4.2 10.5 0.0 1.5 0.1 15.4 2.2 9.0 1.8 3.5 4.9 0.0 3.8 4.3 0.0 0.0 0.1 0.1 9.7 2.2 4.7 0.0 0.0 0.1 0.1 8.1 11.0 1.9 1.0 6.0 0.0 2.6 0.1 20.7 12.4 5.2 1.1 3.5 13.1 0.0 7.5 1.0 0.0 0.6 5.1 0.8 0.0 6.3 10.3 0.0 6.8 0.0 4.6 0.4 0.6 0.8 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.6 0.3 0.3 2.8 0.3 0.6 0.3 0.1 0.1 3.4 5.0 2.1 11.1 3.1 2.8 1.2 3.9 4.5 0.0 PTPN4 PTPMEG ENSG00000088179 "Protein tyrosine phosphatase, non-receptor type 4" P29074 2 119759631-119983818 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 16 "NK-cells: 12.2;T-cells: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019351 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" Nucleoplasm "Plasma membrane, Cytosol" "HPA019351: AB_1855928" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-2)" "unprognostic (9.00e-2)" "unprognostic (9.57e-2)" "unprognostic (2.34e-1)" "prognostic favourable (5.16e-4)" "unprognostic (3.31e-2)" "unprognostic (3.34e-3)" "unprognostic (3.13e-1)" "unprognostic (1.10e-1)" "unprognostic (3.34e-2)" "unprognostic (1.74e-1)" "unprognostic (1.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.81e-1)" 6.8 6.9 10.0 5.9 12.2 7.3 7.2 37.4 16.9 9.6 5.5 7.2 5.2 8.1 7.2 6.6 6.9 8.9 6.3 8.9 10.2 8.4 12.0 6.6 8.0 7.9 7.3 13.1 8.9 6.3 11.6 16.3 4.1 8.3 6.2 4.0 7.1 7.9 6.6 11.2 5.8 5.5 4.7 7.3 9.2 8.9 7.7 6.5 18.9 22.5 6.8 6.5 5.3 5.8 0.5 0.3 0.9 0.4 12.2 19.3 4.7 7.3 4.3 5.7 7.6 5.1 5.3 9.7 3.3 9.4 1.9 5.2 6.4 11.4 5.3 8.0 3.7 6.5 4.4 5.2 5.1 12.3 3.7 3.6 4.1 6.1 3.4 3.7 2.7 4.8 9.8 8.8 4.0 8.3 6.2 5.4 5.0 5.6 5.1 4.3 7.5 7.1 3.5 9.8 7.4 6.9 10.0 7.4 9.2 4.6 5.9 3.8 2.8 2.4 10.4 0.2 6.5 2.2 4.0 9.3 13.0 6.7 4.9 0.2 3.1 0.2 0.2 0.9 19.3 0.3 15.6 0.5 9.6 15.1 0.3 0.5 3.2 11.0 0.7 12.2 0.4 0.3 5.6 4.7 10.0 12.2 37.4 16.9 10.2 8.4 7.3 13.1 8.3 6.5 PTPN5 "PTPSTEP, STEP, STEP61" ENSG00000110786 "Protein tyrosine phosphatase, non-receptor type 5" P54829 11 18727928-18792721 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "brain: 70.0" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HMC-1: 3.6;NTERA-2: 5.7" "Group enriched" "Detected in some" 6 "glioma: 1.6;testis cancer: 2.0" "Region enhanced" "Detected in many" "basal ganglia: 70.0" "Cell type enriched" "Detected in single" 9 "basophil: 1.5" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031014, HPA072091" Supported Approved "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA031014: AB_10669550, HPA072091: " "unprognostic (1.23e-1)" "unprognostic (2.91e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-2)" "unprognostic (3.27e-2)" "unprognostic (2.13e-2)" "unprognostic (5.83e-3)" "unprognostic (3.59e-1)" "unprognostic (4.91e-2)" "unprognostic (2.59e-1)" "unprognostic (2.00e-1)" "unprognostic (3.58e-1)" "unprognostic (8.44e-4)" "unprognostic (4.21e-3)" "unprognostic (3.90e-2)" "unprognostic (9.39e-2)" "unprognostic (8.49e-2)" 2.5 1.6 16.3 1.1 70.0 1.1 1.2 0.9 47.5 1.5 1.1 0.4 0.0 1.1 1.2 1.0 1.3 1.7 1.4 4.3 9.1 8.6 1.1 0.9 2.7 1.1 3.5 16.0 2.5 1.2 1.5 0.5 0.9 6.1 1.6 1.4 0.0 1.3 1.7 1.8 1.0 1.4 1.4 2.1 1.3 1.3 3.4 9.3 0.0 1.2 0.0 1.0 1.5 0.3 0.1 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 5.7 0.3 0.0 0.1 0.1 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 70.0 0.9 25.1 9.1 8.6 3.5 16.0 6.1 9.3 PTPN6 "HCP, HCPH, PTP-1C, SHP-1, SHP1" ENSG00000111679 "Protein tyrosine phosphatase, non-receptor type 6" P29350 12 6946468-6961316 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 107.1;lymphoid tissue: 69.0" "Cell line enhanced" "Detected in many" "HEL: 28.1;HL-60: 24.9;HMC-1: 110.1;THP-1: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001466, CAB004572, CAB072845" Enhanced Supported Nucleoplasm,Nucleoli 7400000 Nucleoplasm Nucleoli "CAB004572: AB_628251, CAB072845: , HPA001466: AB_1855930" "unprognostic (4.28e-3)" "prognostic favourable (1.87e-4)" "prognostic unfavourable (5.42e-4)" "prognostic favourable (6.65e-4)" "unprognostic (6.54e-2)" "unprognostic (7.92e-2)" "unprognostic (2.36e-1)" "unprognostic (1.44e-2)" "unprognostic (6.93e-3)" "unprognostic (3.57e-1)" "unprognostic (1.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.60e-3)" "unprognostic (1.98e-3)" "unprognostic (2.60e-2)" "unprognostic (5.91e-2)" "prognostic favourable (2.64e-8)" 6.6 8.8 2.4 42.9 4.4 27.7 4.6 1.2 2.7 2.8 7.0 5.1 4.7 7.5 3.7 8.8 7.0 5.0 9.8 2.9 3.1 2.3 7.0 6.8 25.4 58.1 5.2 1.8 2.3 6.7 2.7 5.6 7.7 3.9 5.6 5.2 3.6 10.6 7.0 1.3 6.1 21.0 2.6 4.9 69.0 6.6 1.5 3.3 31.4 6.3 4.1 50.7 8.5 4.2 63.9 38.0 107.1 103.2 22.2 28.2 63.2 2.8 5.5 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 2.9 6.4 2.0 1.5 0.0 3.3 0.0 3.8 0.0 1.2 1.1 28.1 0.6 2.4 0.0 24.9 110.1 0.0 2.8 0.0 1.2 0.0 0.0 0.2 0.0 6.0 9.0 14.6 1.5 0.9 8.2 0.0 14.2 3.0 5.4 0.5 0.0 0.9 4.5 0.0 1.4 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 10.9 0.1 54.4 35.9 107.1 28.2 71.3 18.2 62.3 13.7 21.0 38.0 63.9 15.8 19.9 66.7 22.2 103.2 10.0 14.4 63.2 2.4 4.4 1.2 2.7 3.1 2.3 5.2 1.8 3.9 3.3 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase, non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.5;lymphoid tissue: 63.7" "Cell line enhanced" "Detected in some" "HEL: 16.4;HL-60: 35.6;HMC-1: 48.1;NB-4: 15.5;THP-1: 16.4;U-937: 25.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basal ganglia: 9.4;thalamus: 2.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 17.0;NK-cells: 9.9;T-cells: 10.6" "Region enriched" "Detected in single" 10 "basal ganglia: 5.5" "Region enriched" "Detected in all" 4 "basal ganglia: 10.9" "CAB009530, HPA019118" Approved "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favourable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favourable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavourable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 2.6 3.1 0.5 27.1 9.4 24.5 0.6 0.4 0.5 0.6 2.3 0.6 0.0 3.0 0.7 0.6 1.7 0.8 2.9 0.5 0.6 0.8 1.1 0.9 3.2 16.5 1.2 0.2 0.6 0.6 0.0 0.7 0.4 0.8 1.3 1.9 0.7 5.3 0.3 0.4 0.6 3.7 0.9 1.6 15.4 1.4 12.7 2.9 63.7 0.9 0.6 24.8 2.9 0.8 2.6 2.6 17.0 1.1 9.9 10.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 16.4 0.0 0.0 0.0 35.6 48.1 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.0 0.0 4.8 15.5 0.0 0.0 0.7 0.0 12.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16.4 0.0 0.0 0.1 0.0 0.0 7.2 1.8 10.3 0.0 25.7 0.0 11.5 1.1 17.0 10.6 1.1 9.5 1.9 7.1 10.5 2.0 2.6 5.3 6.4 7.1 9.9 0.4 2.6 9.0 2.8 0.5 9.4 0.4 0.5 0.6 0.8 1.2 0.2 0.8 2.9 PTPN9 MEG2 ENSG00000169410 "Protein tyrosine phosphatase, non-receptor type 9" P43378 15 75463251-75579289 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041922 Approved Approved Vesicles Vesicles "HPA041922: AB_10795269" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (7.38e-2)" "unprognostic (5.95e-2)" "unprognostic (3.93e-1)" "unprognostic (3.14e-1)" "unprognostic (9.25e-3)" "unprognostic (6.35e-2)" "prognostic favourable (2.49e-6)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.39e-1)" 16.8 12.8 15.0 11.8 17.7 9.2 15.7 11.1 20.0 17.4 22.4 10.5 12.0 17.0 18.9 16.4 10.9 16.4 13.5 12.2 13.1 14.6 17.9 14.0 16.0 12.6 11.6 12.4 16.0 12.3 16.6 12.5 18.9 13.2 16.9 19.5 18.4 14.6 21.9 6.8 11.8 30.6 17.6 15.6 15.6 13.4 8.7 7.5 16.3 34.4 8.0 13.9 14.7 15.3 3.3 5.9 4.6 5.7 6.7 7.2 2.9 9.1 11.0 17.2 11.5 12.9 14.2 5.7 13.7 21.4 17.4 15.9 6.6 13.9 14.8 11.1 23.4 13.8 37.0 15.8 17.6 18.3 9.4 8.3 7.9 7.0 19.4 12.5 12.8 18.4 16.6 13.9 21.8 14.5 5.5 5.4 19.6 6.0 8.9 11.8 15.8 5.6 17.5 8.5 4.1 21.9 14.8 6.8 14.1 19.5 10.9 21.0 5.6 21.7 16.7 16.7 5.4 10.9 14.6 8.0 8.3 13.8 9.7 19.1 16.4 4.6 4.3 4.2 7.2 5.7 5.7 3.3 5.0 6.1 5.9 2.3 2.1 3.9 0.7 6.7 5.4 3.9 3.1 2.9 15.0 17.7 11.1 20.0 13.1 14.6 11.6 12.4 13.2 7.5 PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase, receptor type A" P18433 20 2864184-3039076 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles 21000 Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: " "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.43e-3)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (3.24e-1)" "unprognostic (7.33e-2)" "unprognostic (1.16e-1)" "prognostic favourable (3.29e-6)" "unprognostic (1.25e-1)" "unprognostic (4.02e-1)" "unprognostic (1.60e-2)" "unprognostic (4.19e-1)" 21.9 18.5 55.6 14.3 48.6 16.4 23.3 44.5 56.0 29.7 19.7 37.5 9.4 14.7 26.3 18.7 22.7 26.5 21.3 14.0 45.9 41.1 22.1 13.5 21.6 16.9 38.0 46.7 28.6 14.9 41.5 23.4 29.0 52.5 23.5 20.0 18.5 16.7 21.8 8.2 21.0 15.3 25.7 52.6 17.9 16.3 27.4 30.4 20.6 32.4 8.5 20.4 22.9 19.2 7.7 5.7 7.9 6.7 6.2 11.0 3.7 20.5 12.6 36.3 11.1 40.2 73.4 7.7 15.5 30.3 19.2 23.5 15.0 28.6 13.5 12.2 20.7 22.1 14.6 22.1 21.7 20.8 9.4 19.2 5.3 19.0 14.4 19.2 9.1 32.8 22.9 15.8 16.7 26.5 19.2 17.3 19.0 8.4 22.2 21.8 14.0 10.1 17.0 17.6 16.8 16.4 16.0 20.1 19.3 15.0 25.5 23.0 15.9 16.5 18.9 17.1 8.5 19.1 13.6 12.7 17.6 17.8 7.9 18.2 16.0 7.9 4.8 7.5 11.0 4.8 9.0 7.7 7.4 7.9 3.7 5.1 7.4 9.0 6.0 6.2 6.7 5.7 8.1 3.7 55.6 48.6 44.5 56.0 45.9 41.1 38.0 46.7 52.5 30.4 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase, receptor type B" P23467 12 70515866-70637440 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in some" "EFO-21: 11.1;HUVEC TERT2: 27.5;TIME: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 7 "memory B-cell: 3.5" "Lineage enriched" "Detected in single" 7 "B-cells: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" 6700000 "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: " "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favourable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favourable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 23.5 7.0 4.5 5.5 7.0 0.1 22.9 3.6 6.1 11.3 8.0 4.3 7.1 5.3 17.1 8.5 5.8 8.2 11.4 17.6 6.2 5.1 18.7 12.0 39.9 3.3 6.9 4.6 5.5 4.4 4.9 5.7 23.3 7.8 6.1 8.2 16.0 3.6 7.1 11.8 4.7 7.4 13.3 7.3 22.9 5.2 3.7 4.3 0.7 14.0 12.2 2.6 6.5 14.7 3.5 0.1 0.2 0.0 0.4 0.3 0.2 1.9 0.1 0.8 0.1 0.0 0.0 0.4 0.4 1.9 1.0 2.4 0.0 1.5 0.7 11.1 0.3 6.8 0.1 0.3 3.5 0.5 0.3 0.1 0.7 0.4 0.1 0.3 0.0 0.0 0.3 2.7 0.0 27.5 1.5 0.4 0.6 0.0 0.0 0.0 1.0 0.4 0.0 0.7 0.3 5.1 0.7 0.0 0.4 0.7 0.0 1.6 0.0 0.6 40.2 0.4 0.4 0.1 2.3 0.5 0.3 0.3 0.2 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 3.5 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.2 4.5 7.0 3.6 6.1 6.2 5.1 6.9 4.6 7.8 4.3 PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase, receptor type D" P23468 9 8314246-10612723 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1;parathyroid gland: 37.5" "Cell line enhanced" "Detected in some" "AF22: 23.0;HAP1: 5.0;HSkMC: 7.8;NTERA-2: 5.6;RH-30: 8.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" 2500000 Vesicles Nucleoplasm "HPA054829: " "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favourable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" 2.6 1.7 19.7 1.5 19.2 1.1 1.1 27.9 32.1 5.6 5.4 21.7 0.2 4.0 3.6 1.8 1.5 3.6 2.6 3.0 18.0 13.5 11.4 4.2 3.4 0.9 17.9 22.3 12.7 1.7 37.5 4.4 9.4 15.1 3.3 5.3 1.9 1.1 2.0 1.0 1.2 4.6 2.8 29.7 1.4 1.7 2.5 18.5 0.0 3.2 0.0 1.0 2.7 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 23.0 0.0 0.3 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 2.6 4.7 0.6 0.0 0.0 0.0 0.2 7.8 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 2.7 0.0 5.6 1.4 2.8 8.5 0.0 2.1 0.0 3.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.7 19.2 27.9 32.1 18.0 13.5 17.9 22.3 15.1 18.5 PTPRE PTPE ENSG00000132334 "Protein tyrosine phosphatase, receptor type E" P23469 10 127907061-128085855 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 91.0" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 19.9;NB-4: 15.0;TIME: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 91.0;plasmacytoid DC: 65.7" "Group enriched" "Detected in all" 11 "dendritic cells: 65.7;granulocytes: 91.0;monocytes: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015870, HPA021872" Supported Approved "Intermediate filaments" "Intermediate filaments" "HPA015870: AB_1855759, HPA021872: AB_1855760" "unprognostic (5.23e-2)" "unprognostic (1.37e-1)" "unprognostic (1.99e-1)" "unprognostic (7.11e-2)" "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (6.50e-2)" "unprognostic (4.49e-2)" "unprognostic (2.11e-1)" "unprognostic (2.56e-2)" "unprognostic (8.71e-3)" "unprognostic (2.00e-1)" "prognostic unfavourable (4.08e-5)" "unprognostic (1.52e-1)" "unprognostic (6.71e-3)" "unprognostic (2.49e-2)" "unprognostic (5.59e-2)" 16.8 18.5 12.5 24.0 12.5 39.5 11.0 7.4 15.3 4.8 9.2 14.5 1.6 9.6 5.1 8.1 8.8 6.2 10.7 12.3 15.0 12.2 4.4 4.8 22.5 20.0 12.5 6.5 4.3 3.1 3.4 6.5 8.0 9.8 4.5 9.8 4.8 7.0 3.1 1.9 4.9 12.7 7.7 14.3 26.4 7.7 4.3 10.9 11.4 6.6 6.1 12.2 10.0 5.0 1.2 65.7 91.0 25.5 4.0 5.4 4.9 2.0 0.4 0.2 0.0 1.2 0.2 3.6 0.0 0.0 0.8 1.7 0.8 12.0 1.5 1.3 1.0 1.1 1.0 5.8 0.3 1.8 0.9 0.1 0.7 0.0 2.0 7.4 5.6 0.4 3.3 2.9 5.9 19.9 0.0 0.9 1.2 1.8 2.2 15.0 0.1 0.7 8.8 1.2 2.9 3.3 8.6 0.0 1.2 3.4 0.6 0.1 0.3 9.4 37.5 0.8 0.8 3.7 4.1 0.4 0.6 2.1 5.5 5.8 0.0 17.4 25.5 19.3 5.4 9.0 3.2 0.9 2.4 3.6 13.3 1.2 1.7 2.9 91.0 4.0 6.8 65.7 3.5 4.9 12.5 12.5 7.4 12.7 15.0 12.2 12.5 6.5 9.8 10.9 PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase, receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 53.7;SK-BR-3: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" 95000000 "Golgi apparatus" "HPA012710: AB_1855933" "unprognostic (8.20e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (9.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.11e-1)" "prognostic unfavourable (3.47e-4)" "unprognostic (4.59e-1)" "unprognostic (1.51e-1)" "unprognostic (4.97e-2)" "unprognostic (4.68e-2)" "unprognostic (7.07e-2)" "unprognostic (1.99e-2)" "prognostic favourable (7.03e-4)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.58e-1)" 37.1 5.5 22.4 10.4 18.1 0.9 30.7 6.8 19.5 14.2 34.3 16.8 34.4 30.7 12.3 33.4 41.4 32.2 20.0 6.3 17.2 15.0 12.0 45.6 15.7 5.8 17.2 18.5 10.4 25.3 17.5 10.3 38.1 16.1 30.9 23.1 5.9 41.9 23.6 2.9 46.8 35.5 16.8 11.2 2.0 21.8 4.3 15.8 4.6 12.5 11.7 14.9 21.4 21.3 0.9 0.0 0.2 0.0 0.0 0.0 0.7 30.4 14.6 9.6 11.3 2.2 0.1 53.7 17.5 7.0 14.5 12.4 15.5 41.5 0.0 4.9 7.6 23.9 11.1 38.5 17.6 0.3 13.9 0.1 10.0 14.1 6.8 0.2 0.2 2.2 22.2 20.8 34.6 21.5 4.7 1.4 5.3 17.6 0.2 0.2 14.5 4.0 10.6 17.0 0.7 5.6 46.1 14.3 5.3 17.4 61.4 2.3 17.7 3.2 16.9 0.3 23.2 1.4 23.3 0.6 0.5 0.0 1.4 0.7 45.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 22.4 18.1 6.8 19.5 17.2 15.0 17.2 18.5 16.1 15.8 PTPRG "PTPG, RPTPG" ENSG00000144724 "Protein tyrosine phosphatase, receptor type G" P23470 3 61561569-62297613 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 35.5;HSkMC: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.3" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000546, HPA064237" Uncertain Approved "Plasma membrane" 520000000 "Plasma membrane" "HPA000546: , HPA064237: " "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (3.26e-1)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-1)" "prognostic favourable (3.10e-6)" "unprognostic (9.91e-2)" "unprognostic (3.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" 22.2 18.0 12.9 10.1 10.7 1.2 26.1 8.1 16.4 17.2 13.9 5.2 12.0 5.6 15.8 19.0 6.4 13.1 15.7 12.4 24.5 9.9 20.2 8.2 38.9 10.2 8.3 10.5 16.6 6.0 58.6 11.9 13.1 15.1 11.3 8.9 23.3 7.9 17.2 19.2 6.6 8.4 17.4 12.7 9.2 8.7 11.4 5.0 0.1 21.7 7.0 3.2 10.0 14.6 1.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.1 11.4 0.0 35.5 18.1 5.5 7.0 11.6 7.5 10.2 5.3 0.2 0.2 4.1 8.3 0.1 5.5 5.5 12.0 0.6 3.1 0.5 0.0 6.1 11.9 2.9 0.0 26.3 2.2 10.7 13.0 8.1 0.0 7.0 6.8 3.0 0.0 0.0 7.0 0.0 4.6 3.5 0.2 7.8 3.3 0.8 1.8 1.7 0.0 2.7 0.0 0.1 18.5 10.6 10.1 16.9 5.9 2.2 2.6 0.0 8.1 1.3 12.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 12.9 10.7 8.1 16.4 24.5 9.9 8.3 10.5 15.1 5.0 PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase, receptor type H" Q9HD43 19 55181248-55209506 "Enzymes, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "gallbladder: 29.6;intestine: 84.3;lymphoid tissue: 21.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 8.0;HHSteC: 10.4;K-562: 12.1;PC-3: 8.2;SK-MEL-30: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in single" "non-classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042300 Approved Mitochondria Mitochondria "HPA042300: AB_10796900" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" 0.5 8.9 0.5 5.2 0.7 0.0 0.5 0.5 1.0 0.7 39.9 0.6 0.5 30.1 0.5 0.5 0.6 0.0 29.6 0.5 1.3 1.6 0.6 7.8 0.6 0.5 3.0 0.5 0.6 2.8 0.0 3.0 0.6 0.5 1.0 9.6 0.6 0.5 0.5 0.5 0.0 84.3 0.7 6.9 21.2 10.2 0.5 0.5 0.5 0.5 1.0 0.8 1.1 2.4 0.0 0.7 0.0 1.5 0.0 0.0 0.0 5.6 3.5 0.0 1.4 1.1 3.1 0.1 0.1 3.0 0.6 1.2 1.5 8.0 0.0 0.3 0.5 0.0 0.0 0.0 0.7 0.0 0.1 0.4 0.1 4.0 10.4 0.0 4.1 0.8 2.5 2.0 3.1 0.1 12.1 0.5 0.0 0.0 0.0 0.2 0.0 8.2 0.0 0.0 0.4 0.0 0.0 0.3 0.8 0.0 3.6 18.2 0.0 1.6 0.0 0.8 1.2 0.4 0.0 0.0 3.0 0.0 0.9 0.1 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.5 0.7 0.5 0.5 1.3 1.6 3.0 0.5 0.5 0.5 PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase, receptor type J" Q12913 11 47980558-48170841 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 25.3;RPTEC TERT1: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in all" 4 "granulocytes: 12.2;monocytes: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved "Intracellular and membrane" 840000000 "HPA006026: AB_1078446" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "unprognostic (9.64e-3)" "unprognostic (3.79e-3)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "prognostic favourable (1.13e-5)" "unprognostic (1.09e-2)" "unprognostic (7.98e-2)" "unprognostic (9.18e-2)" "unprognostic (2.00e-1)" 5.6 3.7 10.4 17.7 13.9 22.6 5.6 4.9 9.5 6.1 9.0 8.8 12.3 8.4 3.9 7.6 2.9 5.0 6.7 5.2 9.5 9.2 13.3 12.2 12.2 22.6 10.8 9.4 3.0 9.1 21.1 14.5 20.3 8.3 7.8 8.1 12.9 12.9 9.0 4.6 4.3 13.4 5.5 6.7 33.0 13.8 3.1 9.9 6.7 18.8 0.9 9.7 6.0 3.9 1.0 1.8 12.2 5.3 1.2 2.1 0.9 3.5 13.4 5.9 3.2 0.9 2.1 2.0 3.6 2.6 6.3 4.7 0.8 19.8 3.3 25.3 9.1 2.7 9.2 0.9 7.7 21.7 2.5 0.9 16.6 1.2 5.8 1.2 20.6 1.5 0.3 1.7 0.4 3.8 1.2 2.1 2.2 7.6 0.0 7.4 4.6 2.1 0.7 0.7 1.7 24.6 5.2 4.0 1.2 10.0 5.7 9.0 6.3 9.1 12.4 5.0 5.2 10.0 10.9 0.5 0.7 5.5 5.7 3.8 18.1 0.9 1.5 3.4 2.1 2.5 1.4 1.0 1.2 1.5 1.0 0.7 1.0 1.3 12.2 1.2 5.3 1.8 1.1 0.9 10.4 13.9 4.9 9.4 9.5 9.2 10.8 9.4 8.3 9.9 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase, receptor type K" Q15262 6 127968779-128520674 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.3;naive B-cell: 4.8;naive CD8 T-cell: 1.6" "Group enriched" "Detected in many" 7 "B-cells: 4.8;T-cells: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" 13000000 "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: , HPA054822: " "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavourable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favourable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 12.0 5.2 18.6 10.7 20.3 1.2 20.9 4.7 24.4 12.2 21.9 25.6 11.2 25.7 12.1 10.3 9.1 13.2 29.6 11.4 17.2 12.6 13.3 23.6 17.4 5.7 20.5 19.3 15.6 25.7 11.4 12.2 17.4 14.9 16.3 23.4 3.9 18.3 17.5 9.1 13.5 27.4 14.6 17.1 6.4 24.6 2.7 23.7 15.3 10.1 6.5 7.6 18.4 15.1 4.8 0.0 0.0 0.0 0.4 1.6 0.2 4.4 4.8 2.9 0.2 6.1 8.2 2.9 12.1 23.5 5.0 4.6 8.0 3.7 0.0 3.7 11.1 12.7 3.0 9.6 7.1 13.4 4.9 0.1 7.4 11.1 7.5 0.0 0.4 6.0 8.9 10.5 14.4 13.7 0.0 0.2 12.3 9.0 6.8 0.0 3.0 6.2 24.5 6.2 0.8 12.4 9.2 15.3 0.0 12.5 14.0 0.7 3.8 0.3 23.1 7.9 5.5 15.3 10.9 0.1 1.6 0.0 10.1 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 4.8 0.4 1.6 0.0 0.4 0.0 0.0 0.1 0.2 18.6 20.3 4.7 24.4 17.2 12.6 20.5 19.3 14.9 23.7 PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase, receptor type M" P28827 18 7566782-8406861 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 34.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "memory CD8 T-cell: 7.2" "Group enriched" "Detected in many" 50 "dendritic cells: 2.7;T-cells: 7.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" 76000000 "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: " "unprognostic (2.59e-1)" "prognostic unfavourable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favourable (1.07e-4)" 31.4 14.1 9.5 6.3 22.2 0.6 23.6 10.4 17.2 11.0 13.6 6.2 28.1 4.7 15.4 10.9 8.1 13.6 18.1 33.5 10.5 15.0 16.9 6.5 22.0 7.8 8.5 12.0 15.7 7.6 16.3 21.9 18.3 23.2 10.6 6.6 18.3 7.4 21.8 26.0 7.3 8.7 14.1 9.3 12.1 11.0 12.2 9.1 2.9 31.1 7.3 6.3 18.6 25.3 0.0 2.7 0.0 0.0 0.0 7.2 1.4 1.5 11.3 5.4 0.0 34.8 24.1 13.1 13.8 12.2 9.3 13.8 10.3 2.4 0.0 13.6 16.6 0.1 0.0 4.8 12.9 0.1 2.5 0.0 7.5 5.0 9.9 0.0 0.1 27.4 10.2 5.1 14.7 9.3 0.0 4.7 7.4 0.2 4.5 0.1 0.9 2.5 0.1 4.7 20.9 22.8 19.4 0.4 3.0 0.4 0.0 11.6 0.0 0.0 9.6 19.2 12.1 9.1 2.4 0.4 0.1 0.0 16.4 0.0 3.5 0.0 0.0 0.0 4.5 0.0 1.8 0.0 6.0 7.2 0.1 0.0 1.7 3.1 0.0 0.0 0.0 2.7 1.0 1.4 9.5 22.2 10.4 17.2 10.5 15.0 8.5 12.0 23.2 9.1 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase, receptor type N2" Q92932 7 157539056-158587788 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6;pancreas: 51.3" "Cell line enhanced" "Detected in some" "AF22: 15.3;HDLM-2: 21.5;NB-4: 22.1;SCLC-21H: 12.2;SH-SY5Y: 12.4;THP-1: 10.8;U-87 MG: 15.1" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 14.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavourable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favourable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 2.1 10.5 20.1 1.7 33.9 1.0 1.1 6.2 40.6 1.7 4.6 2.9 0.0 5.1 2.0 2.9 1.5 6.9 4.7 1.9 18.2 21.3 2.0 1.2 3.1 2.1 11.3 22.3 5.8 51.3 0.5 20.0 1.5 10.3 10.2 3.7 1.5 3.4 2.6 0.8 0.7 4.2 1.6 5.3 7.7 24.2 2.2 5.2 0.0 5.6 0.3 1.7 2.8 0.6 3.4 1.3 14.8 1.1 1.5 3.5 1.1 0.0 0.2 15.3 1.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.6 0.2 0.0 0.4 0.0 0.0 21.5 0.2 0.0 0.0 2.5 0.6 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 6.3 22.1 3.0 0.7 0.0 0.7 0.1 0.0 0.0 12.2 12.4 0.0 0.0 0.0 0.0 10.8 3.2 5.0 1.9 0.0 0.3 0.1 0.0 0.0 15.1 9.0 3.6 8.7 1.1 1.6 0.9 0.1 0.3 2.3 1.5 1.1 1.3 3.4 1.4 0.9 14.8 1.5 0.0 0.2 3.5 1.1 20.1 33.9 6.2 40.6 18.2 21.3 11.3 22.3 10.3 5.2 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase, receptor type O" Q16827 12 15322397-15597399 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;intestine: 28.5;kidney: 21.6" "Cell line enhanced" "Detected in some" "NTERA-2: 9.3;SCLC-21H: 5.7;SH-SY5Y: 11.2;THP-1: 4.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.2;intermediate monocyte: 10.5;memory B-cell: 8.3;myeloid DC: 7.4;naive B-cell: 7.0;naive CD4 T-cell: 2.9;non-classical monocyte: 10.5;plasmacytoid DC: 9.5" "Low lineage specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory region: 215.3" "Low region specificity" "Detected in many" HPA034525 Enhanced "Intracellular and membrane" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 3.3 1.2 16.2 3.1 26.1 0.6 1.1 1.0 15.3 1.7 10.4 1.5 0.0 2.0 4.5 2.1 0.8 1.2 1.6 0.7 11.3 10.6 21.6 1.6 6.7 3.2 4.8 8.8 0.7 0.6 0.6 3.8 4.4 4.0 0.7 28.5 1.1 0.8 1.1 0.5 0.7 1.9 7.1 2.6 3.6 1.0 0.9 3.5 0.0 0.5 0.0 3.5 1.7 0.5 8.3 9.5 0.0 10.5 0.1 2.9 2.7 0.0 0.1 0.5 0.4 0.6 0.1 0.2 0.0 0.0 0.9 2.2 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.3 0.1 0.2 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.7 9.3 0.1 0.0 0.0 0.1 0.2 0.3 5.7 11.2 1.3 0.0 0.1 0.1 4.6 0.0 0.1 0.4 0.0 0.4 1.4 0.1 0.4 0.1 0.3 1.7 0.0 5.2 0.0 0.0 10.5 0.0 8.3 1.7 0.4 7.4 7.0 2.9 1.3 0.0 0.1 10.5 9.5 1.3 2.7 16.2 26.1 1.0 15.3 11.3 10.6 4.8 8.8 4.0 3.5 PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase, receptor type R" Q15256 12 70638073-70920843 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 56.1" "Group enriched" "Detected in some" 5 "HDLM-2: 14.0;RT4: 26.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 56.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "cerebellum: 100.5" "Low region specificity" "Detected in all" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: AB_298890, HPA011851: AB_1855939, HPA071067: " "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.63e-3)" "unprognostic (3.48e-5)" "unprognostic (5.44e-3)" "unprognostic (1.77e-3)" "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (1.37e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (2.72e-1)" "prognostic favourable (1.40e-5)" 0.4 3.8 18.8 1.6 11.3 0.3 0.4 56.1 20.9 0.5 11.2 0.1 0.0 5.1 8.4 0.3 0.4 0.5 1.9 0.4 8.6 4.9 0.4 0.4 0.4 0.4 1.3 13.2 0.4 0.6 0.3 0.9 0.7 3.3 0.5 7.8 0.8 0.4 2.1 0.4 0.4 11.3 4.9 3.1 0.4 4.4 0.4 1.4 0.0 0.4 0.0 0.3 4.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.5 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 26.7 0.1 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 18.8 11.3 56.1 20.9 8.6 4.9 1.3 13.2 3.3 1.4 PTPRS ENSG00000105426 "Protein tyrosine phosphatase, receptor type S" Q13332 19 5158495-5340803 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 40.7;HaCaT: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 82 "plasmacytoid DC: 13.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" 92000000 "Plasma membrane, Cytosol" "HPA054747: " "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favourable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavourable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 59.1 17.3 14.4 9.4 14.8 3.1 32.0 27.6 53.3 28.7 11.4 29.6 14.4 4.6 21.4 15.4 13.3 24.0 22.2 18.6 15.9 15.1 10.7 6.9 13.9 8.6 20.5 12.1 29.2 38.4 10.5 16.6 4.3 12.0 23.1 3.6 28.9 21.5 20.1 11.9 23.8 6.5 17.5 13.8 8.3 12.7 10.8 18.7 4.4 21.1 7.2 7.5 19.1 22.7 0.0 13.4 0.0 0.0 0.0 0.1 0.0 3.6 20.9 18.9 40.7 8.7 7.1 2.5 6.3 7.5 7.7 6.3 0.2 2.0 0.0 15.0 10.6 41.3 5.0 0.0 3.4 0.4 8.0 0.0 8.6 13.0 4.0 0.0 4.7 7.5 1.8 1.6 0.3 0.2 5.8 0.0 3.1 15.4 1.6 3.9 10.6 8.9 0.0 4.2 0.0 1.5 7.3 14.5 19.9 6.0 1.1 11.5 7.3 1.5 0.8 6.9 11.9 15.7 7.6 2.1 0.0 12.0 3.5 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 14.4 14.8 27.6 17.6 15.9 15.1 20.5 12.1 12.0 18.7 PTPRT "KIAA0283, RPTPrho" ENSG00000196090 "Protein tyrosine phosphatase, receptor type T" O14522 20 42072752-43189970 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 23.5;fallopian tube: 17.0" "Cell line enhanced" "Detected in some" "BEWO: 4.5;RPMI-8226: 1.2;SCLC-21H: 2.9;U-266/70: 1.0" "Cancer enhanced" "Detected in many" "breast cancer: 5.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017336, CAB069423" Approved "CAB069423: AB_1622602, HPA017336: AB_1855943" "unprognostic (7.17e-3)" "unprognostic (1.02e-1)" "unprognostic (5.61e-3)" "unprognostic (1.08e-2)" "unprognostic (5.95e-2)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (1.31e-2)" "unprognostic (6.93e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-6)" "unprognostic (3.16e-1)" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.17e-1)" 0.6 0.8 5.0 0.6 11.1 0.5 4.6 1.6 23.5 1.6 0.7 0.9 0.0 1.2 0.5 1.8 0.5 17.0 0.7 0.8 4.7 6.5 0.6 0.9 2.1 1.0 2.2 12.6 0.5 0.9 0.5 4.1 4.6 5.1 0.8 0.6 0.5 2.0 4.6 0.5 0.8 1.0 0.5 1.4 0.7 1.8 2.8 0.9 4.9 0.5 0.0 1.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 11.1 1.6 22.6 4.7 6.5 2.2 12.6 5.1 0.9 PTPRU "FMI, hPTP-J, PCP-2, PTP, PTPRO" ENSG00000060656 "Protein tyrosine phosphatase, receptor type U" Q92729 1 29236516-29326813 "Enzymes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 39.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB011476, HPA039832" Approved "CAB011476: AB_442989, HPA039832: AB_10793923" "unprognostic (7.81e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-3)" "unprognostic (6.13e-2)" "prognostic unfavourable (7.92e-4)" "prognostic unfavourable (8.32e-4)" "unprognostic (3.17e-1)" "unprognostic (1.83e-2)" "unprognostic (1.13e-1)" "unprognostic (4.55e-3)" "unprognostic (3.39e-3)" "unprognostic (6.83e-2)" "unprognostic (1.19e-2)" "unprognostic (6.82e-2)" "unprognostic (4.92e-2)" "unprognostic (3.34e-1)" "unprognostic (2.05e-1)" 6.0 3.2 3.1 1.7 5.8 0.6 16.0 6.7 12.7 24.8 3.7 2.6 6.1 1.3 9.5 4.7 3.9 14.5 7.0 8.9 4.5 5.1 3.9 7.0 11.4 1.2 5.2 5.3 12.2 12.0 12.1 8.1 14.3 21.4 11.0 2.3 18.7 11.3 17.9 14.7 7.3 1.7 6.5 6.6 2.4 4.5 4.4 0.9 0.3 4.9 2.1 2.0 12.2 17.6 0.4 0.0 0.0 0.5 0.0 0.2 0.0 3.1 4.3 0.2 0.6 12.1 0.4 39.7 3.4 3.0 0.1 0.2 3.7 14.1 0.5 6.7 0.6 17.1 15.7 11.0 0.0 0.2 7.9 0.6 4.8 15.7 5.1 0.0 0.7 5.6 5.9 0.0 1.0 0.1 0.1 0.5 3.1 5.2 0.2 0.1 6.5 2.0 0.0 4.6 0.2 4.8 15.8 13.4 17.4 3.4 10.8 2.3 6.4 0.7 2.8 0.6 3.9 1.0 0.4 0.3 0.4 0.0 7.8 0.7 0.8 0.0 0.2 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 3.1 5.8 6.7 12.7 4.5 5.1 5.2 5.3 21.4 0.9 PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase, receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 118.1" "Group enriched" "Detected in some" 9 "AF22: 92.1;NTERA-2: 25.6;WM-115: 40.3" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" 950000 Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavourable (9.36e-4)" 2.0 2.5 33.1 2.3 44.1 1.5 4.0 15.4 118.1 2.4 2.2 19.3 0.0 1.9 1.6 2.0 7.0 1.7 1.9 2.0 39.6 15.9 1.6 1.6 2.1 1.5 18.6 17.8 2.0 3.3 1.5 1.6 1.6 67.6 2.1 2.3 0.8 2.4 2.0 1.5 19.3 1.9 2.4 76.6 2.1 9.8 1.7 23.6 0.0 1.5 1.8 3.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 1.1 0.0 0.1 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 44.1 15.4 39.6 39.6 15.9 18.6 17.8 67.6 23.6 PTRH1 "C9orf115, PTH1" ENSG00000187024 "Peptidyl-tRNA hydrolase 1 homolog" Q86Y79 9 127690348-127724873 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021223 Uncertain "HPA021223: AB_1845798" "unprognostic (6.58e-2)" "unprognostic (7.01e-3)" "unprognostic (3.46e-3)" "unprognostic (2.53e-2)" "unprognostic (7.05e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (3.90e-2)" "unprognostic (1.74e-1)" "unprognostic (6.58e-3)" "unprognostic (8.67e-2)" "unprognostic (4.08e-2)" "unprognostic (5.98e-3)" "unprognostic (5.74e-4)" "unprognostic (1.38e-2)" "unprognostic (1.91e-1)" "unprognostic (1.72e-2)" 14.9 15.0 12.5 8.3 11.9 7.1 9.1 3.9 13.7 9.4 7.8 10.7 12.9 7.7 7.8 16.1 7.8 9.9 12.6 13.1 10.7 9.4 14.5 19.3 7.5 14.7 11.6 8.5 6.2 24.7 8.8 11.0 7.2 8.9 9.9 4.0 8.3 9.3 9.9 13.0 15.1 5.8 6.4 6.2 9.4 12.4 16.1 6.2 7.1 18.8 9.1 5.7 9.4 5.6 8.7 11.4 5.6 14.4 10.5 29.4 12.8 15.7 7.1 1.6 4.3 2.3 3.0 12.4 10.5 2.9 4.0 2.2 3.6 6.0 6.0 14.2 4.3 17.5 1.3 7.6 1.2 8.6 2.4 2.6 8.8 7.1 6.8 3.9 7.1 2.5 8.0 4.9 5.1 8.0 6.7 4.8 4.6 14.5 7.0 5.8 2.2 32.0 6.0 3.5 13.5 7.3 3.5 7.0 6.5 11.3 13.6 7.9 12.2 2.5 9.5 5.9 8.1 20.8 6.5 14.3 7.6 3.9 7.9 3.0 7.0 2.5 13.2 5.6 29.3 14.4 29.3 8.7 15.1 29.4 11.4 7.2 11.1 25.5 1.7 10.5 7.5 10.4 14.2 12.8 12.5 11.9 3.9 13.7 10.7 9.4 11.6 8.5 8.9 6.2 PTRH2 "BIT1, CFAP37, CGI-147, PTH2" ENSG00000141378 "Peptidyl-tRNA hydrolase 2" Q9Y3E5 17 59674636-59707626 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Apoptosis Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012897 Supported Supported Mitochondria Mitochondria "HPA012897: AB_1855949" "unprognostic (2.26e-1)" "unprognostic (2.80e-2)" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.38e-2)" "prognostic unfavourable (1.50e-4)" "unprognostic (6.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.59e-3)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "prognostic unfavourable (1.01e-8)" "unprognostic (5.43e-3)" "unprognostic (6.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.49e-2)" 15.9 22.9 17.1 12.4 17.1 9.9 20.7 12.5 22.1 15.6 17.2 11.8 16.3 11.6 14.3 36.7 16.4 13.8 13.1 12.6 19.3 17.8 14.8 34.7 12.1 12.5 16.7 15.2 14.2 19.9 10.3 18.3 13.6 21.0 15.9 20.7 8.1 13.7 18.7 23.3 11.4 11.0 16.8 17.1 15.5 14.3 15.7 18.1 9.0 11.8 13.5 16.9 13.0 10.5 15.6 21.6 12.6 29.3 13.1 15.5 13.0 19.8 37.9 12.2 11.1 23.2 20.0 13.1 19.1 16.9 16.4 24.0 24.4 15.6 14.4 29.0 16.0 19.8 26.2 24.6 23.9 27.7 35.7 25.7 19.7 44.8 35.8 22.7 14.6 22.5 32.1 25.4 29.6 27.2 28.6 16.1 24.3 47.9 19.4 18.5 10.5 30.0 10.6 20.5 21.0 27.3 28.6 15.8 20.5 9.9 10.8 23.4 25.2 16.2 17.9 21.4 21.7 12.8 20.7 20.9 23.2 21.4 14.1 14.2 16.3 1.9 25.8 1.1 9.2 24.4 12.4 15.6 10.8 10.4 18.5 13.1 15.5 11.1 12.6 13.1 29.3 21.6 12.3 13.0 17.1 17.1 12.5 22.1 19.3 17.8 16.7 15.2 21.0 18.1 PTRHD1 "C2orf79, LOC391356" ENSG00000184924 "Peptidyl-tRNA hydrolase domain containing 1" Q6GMV3 2 24789734-24793382 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019951 Approved Approved Nucleoplasm 55000 Nucleoplasm "HPA019951: AB_1853109" "unprognostic (1.28e-2)" "unprognostic (5.79e-2)" "unprognostic (6.34e-2)" "unprognostic (1.34e-2)" "unprognostic (2.61e-2)" "unprognostic (3.99e-1)" "unprognostic (8.84e-3)" "unprognostic (1.26e-1)" "unprognostic (3.69e-1)" "unprognostic (8.31e-3)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "prognostic unfavourable (2.31e-4)" "unprognostic (2.93e-1)" "unprognostic (1.55e-1)" "unprognostic (1.51e-1)" "unprognostic (5.76e-2)" 8.2 20.0 19.4 10.8 16.2 20.4 13.3 4.6 13.0 6.7 13.6 8.5 7.8 16.1 5.6 11.9 12.7 8.2 10.2 15.8 15.6 14.4 11.3 16.0 9.2 17.6 16.9 8.8 8.5 28.1 2.7 8.4 12.2 10.4 11.0 9.4 7.6 25.9 7.5 30.1 10.3 15.0 5.6 15.5 10.4 11.7 25.2 6.9 17.5 15.6 19.9 12.9 8.3 8.4 29.1 44.1 8.2 27.9 14.5 23.7 26.1 8.0 19.4 6.3 2.7 3.6 8.0 10.9 5.9 5.7 7.8 5.0 19.1 7.7 6.8 2.5 6.3 5.4 5.2 5.5 2.6 9.2 35.0 12.3 9.4 20.8 7.4 10.0 11.5 7.6 4.5 3.6 4.0 7.2 12.2 5.4 5.7 17.7 8.2 18.7 13.2 11.7 6.7 19.2 11.2 9.0 15.2 9.8 15.2 6.5 8.8 7.6 8.5 7.6 11.8 6.6 10.3 3.1 5.0 4.3 13.1 7.3 6.2 6.3 4.5 8.2 27.9 5.9 16.6 19.0 8.5 29.1 16.4 14.5 42.9 22.1 15.3 17.8 3.2 14.5 13.7 44.1 23.7 26.1 19.4 16.2 4.6 13.0 15.6 14.4 16.9 8.8 10.4 6.9 PUDP "DXF68S1E, FAM16AX, GS1, HDHD1, HDHD1A" ENSG00000130021 "Pseudouridine 5'-phosphatase" Q08623 X 7048920-7148190 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" HPA072672 Approved 14000 "HPA072672: " "unprognostic (1.84e-1)" "unprognostic (4.93e-2)" "unprognostic (5.15e-3)" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (5.63e-3)" "unprognostic (1.00e-3)" "unprognostic (3.22e-2)" "unprognostic (4.86e-2)" "unprognostic (4.85e-2)" "prognostic unfavourable (7.27e-4)" "unprognostic (2.24e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-1)" "unprognostic (2.92e-2)" "prognostic favourable (4.80e-4)" "unprognostic (3.42e-2)" 10.8 9.3 10.2 10.3 12.5 2.6 7.5 7.8 10.5 9.1 15.0 9.7 9.1 15.2 8.6 6.3 9.9 17.0 7.1 17.1 8.1 10.6 19.8 10.1 10.3 13.1 12.5 7.1 9.6 8.9 7.3 11.2 42.4 10.0 7.4 10.5 8.3 9.8 6.9 31.8 5.0 15.1 9.8 10.6 11.2 15.8 7.7 11.4 13.3 10.4 8.9 13.1 10.2 8.9 7.0 11.1 2.1 14.9 5.1 9.6 7.5 19.9 18.8 29.8 12.4 15.2 15.0 5.1 7.1 6.9 7.9 8.1 26.7 12.3 9.2 14.8 7.1 6.1 13.5 16.0 12.3 8.2 26.0 9.7 7.1 14.6 7.2 8.5 11.0 7.8 6.2 21.5 10.0 23.6 18.6 8.4 12.5 9.3 9.5 12.6 15.7 9.3 7.1 11.5 24.9 11.4 7.5 7.1 7.5 5.7 10.6 10.6 11.8 8.0 9.1 4.9 3.0 20.4 6.0 26.8 0.1 15.0 7.0 4.9 9.5 2.1 14.4 1.6 6.4 14.9 6.4 7.0 6.8 6.0 11.1 5.2 5.2 5.8 1.5 5.1 14.0 3.6 9.6 7.5 10.2 12.5 7.8 10.5 8.1 10.6 12.5 7.1 10.0 11.4 RAD1 "HRAD1, REC1" ENSG00000113456 "RAD1 checkpoint DNA exonuclease" O60671 5 34905264-34918989 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006692 Approved Supported Nucleoplasm,Vesicles "Nucleoplasm, Vesicles" "HPA006692: " "prognostic unfavourable (6.30e-4)" "unprognostic (1.85e-2)" "unprognostic (9.40e-2)" "unprognostic (1.98e-3)" "unprognostic (2.00e-1)" "unprognostic (2.38e-2)" "prognostic unfavourable (1.06e-5)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.61e-3)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.11e-1)" "unprognostic (3.12e-3)" 3.1 6.5 3.4 3.2 4.9 4.8 4.4 5.2 4.7 5.4 3.2 2.9 4.6 3.8 3.7 3.5 3.3 6.6 3.5 4.4 3.7 3.5 5.6 6.1 2.9 4.0 3.3 3.0 3.4 6.0 5.3 3.1 4.3 3.7 7.4 4.5 3.6 3.3 2.6 3.1 3.7 5.8 5.2 4.7 3.8 4.7 9.4 7.6 7.2 3.1 4.8 9.3 2.6 5.8 6.8 7.2 14.0 5.1 5.9 10.4 9.2 9.0 9.7 8.0 6.4 8.0 15.2 3.3 8.2 5.4 7.9 5.6 10.9 6.8 6.8 8.1 20.7 4.3 8.7 11.1 7.5 5.3 4.8 10.5 7.0 4.6 14.4 9.0 8.2 7.2 11.3 7.9 9.4 10.3 10.4 15.2 5.3 4.7 6.2 7.5 7.9 19.0 13.0 8.5 8.0 9.3 4.2 12.7 9.6 6.5 9.6 5.0 9.1 13.4 6.6 16.8 8.8 7.2 3.0 6.8 5.9 3.1 7.7 8.7 6.5 8.0 2.9 9.4 9.3 8.0 2.3 4.8 2.9 7.6 5.3 2.6 RAD54L2 "ARIP4, KIAA0809, SRISNF2L" ENSG00000164080 "RAD54 like 2" Q9Y4B4 3 51541144-51668667 "Enzymes, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035004, HPA039992, HPA077351" Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA035004: AB_10671930, HPA039992: , HPA077351: " "unprognostic (1.46e-2)" "unprognostic (3.67e-2)" "unprognostic (2.61e-1)" "unprognostic (5.01e-2)" "unprognostic (1.15e-1)" "unprognostic (4.38e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-2)" "unprognostic (9.24e-2)" "unprognostic (2.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.51e-1)" "prognostic favourable (1.71e-5)" "unprognostic (3.72e-2)" "unprognostic (3.19e-1)" "unprognostic (3.30e-2)" "unprognostic (6.63e-2)" 4.4 4.1 3.3 3.5 4.3 5.2 4.1 7.8 4.3 3.6 4.4 2.2 5.3 4.6 3.6 3.9 2.5 3.1 3.4 3.5 3.4 8.8 4.2 3.8 3.4 5.6 5.0 5.3 3.9 4.9 3.8 3.5 3.7 4.2 7.3 4.6 4.1 4.3 4.1 4.7 4.4 4.7 4.2 5.2 3.8 3.5 6.9 5.2 6.5 7.1 6.3 8.3 4.0 5.6 4.4 11.4 11.2 6.4 4.6 6.0 4.8 6.8 6.6 6.3 7.8 3.3 14.8 1.4 8.4 4.4 17.9 6.0 8.2 7.8 4.0 12.7 9.5 5.1 5.8 14.1 7.6 5.2 4.8 10.1 9.8 7.3 8.3 8.1 5.2 4.3 12.6 6.4 9.0 4.8 5.8 8.8 2.0 3.3 7.3 4.7 8.9 7.6 7.3 4.9 4.8 8.5 9.5 7.0 8.0 7.1 9.3 8.7 8.8 15.0 7.5 8.0 8.8 6.5 4.8 4.7 8.1 6.0 8.3 4.3 7.1 6.6 5.2 6.9 4.7 5.4 2.2 6.3 7.1 5.2 6.3 4.0 RAD9A RAD9 ENSG00000172613 "RAD9 checkpoint clamp component A" Q99638 11 67317871-67398410 "Enzymes, Predicted intracellular proteins" "DNA damage" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006725, HPA048155" Enhanced Enhanced Nucleoplasm Nucleoplasm "HPA006725: AB_1856041, HPA048155: " "unprognostic (7.64e-2)" "prognostic favourable (6.95e-4)" "unprognostic (8.83e-3)" "unprognostic (1.13e-1)" "unprognostic (2.68e-1)" "unprognostic (2.12e-3)" "unprognostic (9.64e-3)" "unprognostic (1.05e-2)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (9.19e-2)" "unprognostic (2.50e-2)" "prognostic unfavourable (2.82e-5)" "unprognostic (6.16e-2)" "unprognostic (3.72e-3)" "unprognostic (2.19e-1)" "prognostic favourable (7.52e-6)" 5.4 5.2 7.0 10.6 8.4 10.8 6.1 7.7 6.3 6.7 11.8 8.5 5.1 14.2 7.1 4.1 8.2 12.1 6.3 6.1 3.8 3.5 6.9 9.4 9.5 9.0 7.8 2.5 6.8 20.1 3.7 7.2 10.2 5.5 8.6 3.3 4.9 12.8 8.1 7.8 12.8 17.5 5.5 4.1 10.7 11.3 7.2 6.0 18.2 11.7 7.2 16.8 6.2 7.1 6.7 5.1 8.9 3.9 4.7 9.0 3.2 6.7 11.0 5.8 8.3 1.7 0.8 7.8 4.3 2.9 5.0 4.3 13.1 12.9 8.1 8.1 0.9 11.4 3.4 3.3 0.7 7.7 9.5 10.9 5.9 6.5 2.4 7.1 14.4 2.1 3.4 4.3 1.8 3.3 8.8 9.0 1.0 20.9 13.8 13.8 8.8 8.3 11.5 7.9 9.2 1.3 5.4 6.7 7.2 6.0 16.5 13.6 11.6 6.8 2.5 7.2 9.4 14.6 5.1 9.6 8.9 7.1 4.8 7.0 5.9 8.0 3.2 8.9 9.0 3.6 6.4 6.7 7.2 7.3 2.1 5.3 4.9 5.7 4.7 4.7 3.9 5.1 3.9 3.2 7.0 8.4 7.7 6.3 3.8 3.5 7.8 2.5 5.5 6.0 RECQL "RecQ1, RecQL1" ENSG00000004700 "RecQ like helicase" P46063 12 21468911-21501669 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009743, HPA030960, HPA064259" Enhanced Enhanced Nucleoplasm Nucleoplasm "CAB009743: AB_655306, HPA030960: AB_10794912, HPA064259: " "unprognostic (9.70e-3)" "unprognostic (2.55e-2)" "unprognostic (1.86e-2)" "unprognostic (6.25e-3)" "unprognostic (2.47e-1)" "unprognostic (1.39e-1)" "unprognostic (8.97e-3)" "unprognostic (1.89e-3)" "unprognostic (8.74e-2)" "prognostic unfavourable (3.15e-4)" "unprognostic (3.77e-3)" "unprognostic (3.78e-2)" "unprognostic (2.85e-1)" "unprognostic (1.27e-1)" "unprognostic (1.09e-1)" "unprognostic (2.99e-1)" "unprognostic (3.69e-2)" 32.7 15.8 10.0 22.0 12.7 10.8 18.2 10.9 11.2 18.0 16.3 9.4 11.0 7.5 19.8 14.4 18.7 14.6 14.1 17.9 11.2 7.2 19.6 18.0 19.5 25.7 15.3 7.6 16.0 11.9 8.0 14.8 17.1 12.0 14.0 12.7 6.7 13.1 12.4 15.0 12.4 15.5 20.5 19.5 34.0 12.9 10.8 13.0 27.4 17.4 14.3 25.0 22.6 13.0 19.3 15.2 11.3 20.7 23.1 28.0 13.8 17.5 17.8 13.5 10.0 27.4 34.5 15.7 34.0 28.7 21.9 25.6 19.5 14.7 21.1 13.1 23.1 12.9 14.4 16.9 31.3 35.3 9.6 25.7 19.8 8.2 10.6 17.8 19.5 19.2 8.7 31.1 22.9 24.6 9.0 10.3 28.8 8.5 19.5 20.8 22.5 12.1 16.1 54.9 16.3 8.4 12.1 3.6 10.8 25.3 6.8 17.8 17.3 11.4 33.1 30.9 20.1 27.0 31.5 4.2 12.4 46.3 26.1 10.5 22.7 9.3 11.8 11.3 21.9 20.7 21.3 19.3 20.5 21.0 15.2 16.0 13.6 18.8 5.5 23.1 18.8 11.6 28.0 13.8 10.0 12.7 10.9 11.2 11.2 7.2 15.3 7.6 12.0 13.0 RECQL5 "FLJ90603, RecQ5" ENSG00000108469 "RecQ like helicase 5" O94762 17 75626845-75667189 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, DNA replication" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029971 Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA029971: AB_10611389" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "prognostic unfavourable (1.73e-6)" "unprognostic (8.39e-2)" "unprognostic (2.34e-2)" "unprognostic (3.57e-3)" "unprognostic (5.83e-2)" "unprognostic (3.15e-1)" "unprognostic (5.84e-2)" "prognostic favourable (4.34e-4)" "unprognostic (4.07e-2)" "unprognostic (7.01e-2)" "unprognostic (6.37e-2)" "unprognostic (1.42e-1)" "unprognostic (4.78e-1)" "unprognostic (1.81e-2)" 7.4 12.9 12.6 11.7 16.0 10.0 9.8 11.4 17.7 9.4 10.6 24.4 17.4 22.9 10.5 13.2 20.4 11.8 12.4 6.7 12.9 8.6 14.9 15.8 8.4 16.8 14.5 11.0 14.3 10.8 17.6 21.9 32.3 14.3 12.2 9.8 13.2 15.6 14.0 6.8 21.1 23.2 9.6 13.2 16.6 23.8 21.0 17.0 12.1 21.4 6.2 16.0 12.1 12.8 5.2 16.4 6.0 3.9 3.8 4.2 3.2 11.0 20.5 8.3 11.7 11.6 7.8 19.1 8.2 6.9 10.7 9.5 9.0 11.8 13.1 8.9 7.2 10.5 8.6 9.8 10.2 7.0 16.1 23.9 24.8 13.0 11.6 7.7 11.9 11.0 12.1 10.6 12.8 13.9 12.0 11.7 7.9 9.8 15.8 10.5 5.4 15.9 12.8 19.4 13.2 9.0 13.2 10.0 9.7 8.9 16.1 11.0 28.9 6.2 7.0 13.8 15.9 7.5 8.4 16.7 9.5 12.6 11.3 7.7 9.9 6.0 3.1 4.4 4.2 3.9 2.7 3.6 2.7 3.1 3.8 5.2 4.1 2.9 2.1 3.8 1.9 16.4 2.2 3.2 12.6 16.0 11.4 17.7 12.9 8.6 14.5 11.0 14.3 17.0 REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 63.6" "Cell line enhanced" "Detected in some" "A-431: 2.3;BJ: 4.8;HMC-1: 6.3;RT4: 1.8;SK-BR-3: 4.5" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Region enriched" "Detected in single" 12 "basal ganglia: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005131, CAB025903" Approved "Secreted to blood" 692000 "CAB025903: , HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavourable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" 0.4 0.3 0.0 0.0 1.2 0.0 0.5 0.0 0.0 3.1 0.2 0.0 0.8 0.1 4.4 13.5 0.1 0.3 0.0 0.6 0.0 0.0 63.6 0.4 0.3 0.0 0.0 0.0 11.6 0.0 0.0 0.4 14.4 0.0 0.3 0.1 0.4 0.3 0.5 0.0 0.0 0.1 1.0 0.0 0.0 0.0 2.0 0.0 0.0 1.1 0.0 0.2 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 4.8 0.9 0.0 0.0 0.1 0.6 0.0 0.3 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 6.3 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.8 0.2 0.1 0.0 4.5 0.2 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RGN "RC, SMP30" ENSG00000130988 Regucalcin Q15493 X 47078355-47093314 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 51.0;liver: 118.8" "Cell line enhanced" "Detected in some" "CACO-2: 16.1;fHDF/TERT166: 5.1;Hep G2: 24.1" "Cancer enriched" "Detected in many" 6 "liver cancer: 47.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029102, HPA029103" Enhanced Approved Nucleoplasm 47000 Nucleoplasm "HPA029102: AB_10599846, HPA029103: AB_10602097" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (5.56e-3)" "unprognostic (8.22e-3)" "unprognostic (1.32e-2)" "prognostic favourable (7.55e-4)" "unprognostic (2.60e-3)" "unprognostic (2.23e-2)" "unprognostic (8.38e-2)" "unprognostic (3.37e-2)" "unprognostic (1.14e-2)" "prognostic favourable (5.10e-10)" "unprognostic (1.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.82e-2)" "unprognostic (5.22e-2)" 2.6 51.0 6.7 0.6 6.5 0.4 1.5 8.4 6.2 2.8 1.9 6.2 2.5 4.5 2.3 6.1 1.5 1.7 2.0 4.5 6.1 4.2 17.6 118.8 4.9 0.7 5.9 4.5 7.5 12.7 6.2 2.5 4.2 5.0 4.8 1.1 8.4 7.5 6.3 3.8 0.6 4.6 4.9 4.4 1.1 2.9 1.5 5.2 0.0 6.5 1.6 0.6 2.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.3 0.6 0.0 0.0 16.1 0.0 0.0 0.8 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.1 0.8 0.1 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.7 6.5 8.4 6.2 6.1 4.2 5.9 4.5 5.0 5.2 RHBDD1 DKFZp547E052 ENSG00000144468 "Rhomboid domain containing 1" Q8TEB9 2 226835581-226999215 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013972, HPA057125" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "HPA013972: AB_2178629, HPA057125: " "unprognostic (1.42e-1)" "unprognostic (5.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.23e-2)" "unprognostic (2.57e-1)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-1)" "unprognostic (9.40e-2)" "unprognostic (4.74e-3)" "unprognostic (4.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (9.77e-2)" "unprognostic (3.04e-2)" 12.7 14.8 10.8 16.7 16.0 11.0 13.6 8.3 13.0 13.8 14.3 21.2 9.4 11.0 20.6 16.3 13.6 15.4 12.4 14.5 11.4 9.0 13.6 16.9 12.6 17.7 17.6 11.0 18.8 20.4 18.6 17.1 10.5 13.0 15.7 12.4 13.1 14.3 15.5 13.9 13.0 17.5 15.6 16.5 17.3 13.2 25.6 14.7 56.6 17.3 8.8 18.9 18.7 15.4 19.9 16.6 9.8 15.5 8.8 12.5 8.5 5.1 4.4 4.7 7.2 14.3 14.2 0.0 12.2 9.8 6.0 6.9 3.8 8.9 4.8 10.2 12.3 6.0 0.0 12.7 11.6 12.3 4.9 7.0 2.9 3.4 15.4 7.5 4.1 13.3 18.6 11.5 25.1 4.6 18.9 12.6 6.3 9.8 12.7 3.8 0.0 4.7 5.5 0.0 7.0 4.9 6.2 4.6 3.5 6.7 2.4 9.0 6.8 8.6 6.1 2.8 6.2 10.5 3.5 14.1 6.6 34.7 8.9 9.1 8.0 8.1 11.1 9.8 6.1 15.5 9.7 17.3 9.6 7.5 13.7 19.9 10.8 8.9 2.5 8.8 10.3 16.6 12.5 8.5 10.8 16.0 8.3 13.0 11.4 9.0 17.6 11.0 13.0 14.7 RHBDL1 "RHBDL, RRP" ENSG00000103269 "Rhomboid like 1" O75783 16 675666-678268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.3" "Cell line enhanced" "Detected in many" "HeLa: 9.1;MCF7: 9.6;U-266/70: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 3.4" "Group enriched" "Detected in many" 20 "B-cells: 2.2;NK-cells: 1.3;T-cells: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030359, HPA030360, HPA046593" Uncertain Approved Nucleoplasm Nucleoplasm "HPA030359: , HPA030360: , HPA046593: " "prognostic favourable (8.12e-4)" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.45e-1)" "unprognostic (2.07e-1)" "unprognostic (1.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.78e-1)" "unprognostic (6.60e-3)" "unprognostic (2.74e-2)" "unprognostic (3.97e-2)" "unprognostic (5.63e-3)" "unprognostic (5.89e-2)" "unprognostic (1.27e-1)" "unprognostic (8.30e-3)" "unprognostic (1.49e-2)" 1.7 6.3 10.0 1.1 8.3 2.3 0.7 21.3 14.5 1.3 2.2 1.3 2.2 5.8 1.3 1.7 1.1 1.0 1.2 2.4 8.4 9.9 3.9 1.2 0.8 1.1 5.5 7.2 0.9 6.2 2.2 4.4 1.1 4.6 1.5 1.1 1.5 6.1 2.6 0.8 3.1 5.9 0.7 2.2 0.6 4.5 2.2 1.9 0.7 0.6 0.6 0.5 0.8 0.5 2.2 0.1 0.0 0.0 1.3 3.4 0.7 1.7 2.3 1.3 2.0 1.0 2.6 6.7 0.8 1.2 0.4 0.1 4.7 1.3 0.7 1.6 0.5 1.2 0.1 0.4 0.0 1.7 8.5 1.0 9.1 1.9 0.9 1.7 1.3 1.8 3.2 0.3 0.0 0.1 1.3 1.3 0.1 9.6 0.4 4.6 1.2 0.7 8.1 1.2 1.7 0.1 1.6 1.6 2.2 1.0 0.5 2.2 3.5 4.8 0.5 2.8 2.6 0.9 0.6 11.7 1.6 2.3 1.0 3.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 0.3 0.0 0.5 0.5 0.2 0.0 1.3 0.0 0.1 1.2 0.7 10.0 8.3 21.3 14.5 8.4 9.9 5.5 7.2 4.6 1.9 RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941799 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 26.0;HaCaT: 13.5;RT4: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA043807 Approved "HPA043807: AB_10961118" "unprognostic (3.34e-2)" "unprognostic (2.96e-1)" "unprognostic (4.57e-2)" "unprognostic (2.56e-1)" "unprognostic (7.26e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (5.81e-2)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" "unprognostic (4.07e-3)" "unprognostic (1.23e-1)" "unprognostic (7.47e-9)" "unprognostic (1.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.12e-2)" "unprognostic (4.20e-2)" 1.4 0.0 2.9 6.7 2.7 0.0 1.5 0.4 4.0 5.5 14.9 1.7 0.4 0.7 1.9 0.7 18.9 0.7 6.9 4.9 4.2 2.1 0.5 0.4 2.1 1.5 4.9 0.7 1.2 2.4 0.0 0.4 1.0 1.6 3.1 14.7 0.8 8.2 0.4 0.4 13.4 0.9 0.9 7.9 0.6 12.3 8.4 0.4 1.3 0.4 12.2 16.4 6.9 8.2 1.7 2.1 5.3 1.7 0.9 0.9 0.7 8.0 3.2 0.2 0.1 0.1 1.0 0.9 0.4 0.1 0.6 0.0 0.5 26.0 0.2 1.9 3.7 13.5 0.0 4.8 0.3 0.1 0.1 0.1 2.0 1.7 0.5 0.0 0.3 0.6 0.6 3.9 0.0 0.8 0.0 0.2 0.5 0.0 0.0 0.1 0.2 0.7 0.1 0.1 0.0 0.0 26.1 0.2 0.1 2.8 6.6 0.2 3.4 0.2 0.5 2.9 0.3 0.2 0.2 0.2 0.3 0.3 2.5 0.4 0.1 3.6 1.7 1.1 0.8 1.1 0.4 1.7 0.6 0.5 1.9 1.1 0.7 0.7 5.3 0.9 0.7 2.1 0.9 0.7 2.9 2.7 0.4 1.5 4.2 2.1 4.9 0.7 1.6 0.4 RHBDL3 "RHBDL4, VRHO" ENSG00000141314 "Rhomboid like 3" P58872 17 32266176-32324661 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7" "Cell line enhanced" "Detected in some" "A549: 5.9;AF22: 5.9;AN3-CA: 4.7;HDLM-2: 8.1;NTERA-2: 8.8;U-2 OS: 6.2" "Cancer enhanced" "Detected in some" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059607 Uncertain "HPA059607: " "unprognostic (7.70e-2)" "unprognostic (3.71e-2)" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.91e-1)" "unprognostic (2.83e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "unprognostic (2.18e-3)" "unprognostic (2.11e-1)" "unprognostic (1.23e-1)" "unprognostic (8.87e-2)" 1.0 8.2 6.8 1.2 7.4 0.7 1.1 11.3 23.7 1.4 1.2 2.9 3.3 0.9 2.0 1.9 1.3 4.4 0.9 9.7 10.1 6.6 0.8 0.6 0.7 0.7 9.1 4.6 3.4 1.1 0.6 1.9 1.0 6.7 2.1 1.4 3.9 1.0 5.6 0.6 0.9 0.9 1.8 3.6 0.6 0.9 2.5 4.0 0.0 0.6 0.0 0.8 1.9 1.1 0.8 0.0 0.0 0.0 0.0 0.3 0.3 0.0 5.9 5.9 4.7 0.9 0.0 0.1 0.3 0.6 1.9 2.0 0.1 0.0 0.0 0.4 0.7 0.1 1.6 0.0 0.5 8.1 2.3 1.0 4.0 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.5 0.1 0.2 0.0 8.8 0.0 1.0 0.0 0.0 0.0 3.2 0.1 1.6 0.8 0.1 0.1 0.4 0.1 0.0 0.0 6.2 0.3 3.0 0.0 0.0 0.0 0.3 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 6.8 7.4 11.3 15.6 10.1 6.6 9.1 4.6 6.7 4.0 RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117241 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "kidney: 81.4;liver: 248.6" "Low cell line specificity" "Detected in all" "Cancer enhanced" "Detected in all" "liver cancer: 162.2" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced 5700000 "HPA022856: AB_1858253, HPA023489: AB_1858252" "unprognostic (1.67e-2)" "unprognostic (3.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "prognostic favourable (9.61e-6)" "unprognostic (6.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-2)" "unprognostic (1.51e-2)" 8.3 9.4 16.8 2.5 18.8 1.6 4.2 5.6 11.6 2.6 4.7 4.5 2.7 5.8 2.1 4.8 2.8 2.2 4.3 5.2 11.7 12.5 81.4 248.6 2.2 2.1 19.1 9.5 4.6 5.2 3.5 1.8 2.4 11.8 4.0 4.8 2.3 3.2 2.7 6.8 2.3 4.2 2.5 7.9 1.8 4.6 3.3 9.5 0.6 3.2 3.5 2.6 3.2 1.8 12.1 10.0 5.0 8.3 8.4 12.8 7.1 17.1 14.9 12.1 14.7 27.3 21.3 13.2 15.9 11.2 10.6 12.8 20.2 11.5 24.4 20.4 11.6 12.2 26.4 22.5 21.5 8.5 11.4 17.7 10.1 21.6 12.5 6.5 2.8 18.4 7.8 14.9 16.4 13.7 31.5 5.3 14.2 22.3 13.8 17.8 19.0 27.3 16.0 8.8 7.0 25.6 12.4 13.1 6.5 10.1 7.0 11.0 17.9 8.6 8.3 8.3 5.2 13.9 6.3 12.7 17.4 12.0 14.4 13.8 5.3 0.1 8.3 5.0 6.5 7.0 8.3 12.1 9.4 9.5 10.0 9.5 12.2 12.8 1.5 8.4 7.0 7.6 12.3 7.1 16.8 18.8 5.6 11.6 11.7 12.5 19.1 9.5 11.8 9.5 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20803278 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "pancreas: 809.6" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 73.2;RT4: 28.7;TIME: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 8.0;myeloid DC: 16.1" "Group enriched" "Detected in many" 9 "dendritic cells: 16.1;monocytes: 8.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" 1500000000 Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 79.2 48.4 28.7 12.0 38.5 1.6 59.7 4.0 32.2 21.3 33.7 57.8 63.6 16.8 13.6 49.1 19.3 24.3 37.5 70.3 41.2 21.6 33.8 8.6 94.3 23.5 39.0 16.0 19.2 809.6 6.7 4.1 79.0 25.1 23.0 39.8 106.4 15.9 35.6 31.7 10.8 20.6 26.6 52.3 34.5 87.9 86.5 27.1 7.8 11.2 14.3 7.2 29.0 10.9 0.0 16.1 1.3 8.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 73.2 7.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.3 0.0 28.7 0.3 0.3 0.0 0.2 0.0 0.0 0.0 38.0 0.0 0.6 0.4 0.0 0.1 0.0 0.0 1.0 0.0 1.0 1.3 8.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.1 0.0 0.0 3.7 0.0 2.0 28.7 38.5 4.0 32.2 41.2 21.6 39.0 16.0 25.1 27.1 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955452-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "blood: 137.2;bone marrow: 236.7" "Group enriched" "Detected in some" 318 "HL-60: 53.6;NB-4: 53.6;THP-1: 143.6;U-937: 130.2" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 37.8;eosinophil: 137.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 137.2" HPA044983 Enhanced "Secreted to blood" 300000000 "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavourable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 2.7 3.2 4.8 2.0 9.3 236.7 0.5 0.9 3.7 0.9 0.6 1.4 0.1 0.5 0.7 0.5 0.5 3.2 0.9 3.7 3.9 1.8 1.2 1.3 6.6 7.2 4.7 0.1 0.5 2.5 0.5 0.6 0.8 4.9 0.5 0.6 0.1 0.7 0.5 0.9 0.9 0.6 2.1 10.5 19.4 0.9 0.6 3.7 0.1 0.5 0.1 0.6 1.4 0.3 0.0 20.0 137.2 11.5 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 53.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 143.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 130.2 0.0 37.8 11.5 137.2 0.0 2.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 1.0 0.0 0.2 0.2 0.0 3.3 4.8 9.3 0.9 3.7 3.9 1.8 4.7 0.1 4.9 3.7 RNASEH1 ENSG00000171865 "Ribonuclease H1" O60930 2 3544793-3558616 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease mutation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" HPA043037 Uncertain "Intracellular and membrane" "HPA043037: " "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "unprognostic (8.81e-3)" "unprognostic (4.32e-3)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "prognostic unfavourable (7.83e-6)" "unprognostic (9.43e-2)" "unprognostic (8.46e-3)" "unprognostic (6.38e-2)" "unprognostic (2.29e-3)" "unprognostic (2.67e-1)" "unprognostic (4.06e-2)" "unprognostic (2.34e-2)" "unprognostic (2.11e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-3)" 16.6 12.8 10.1 14.5 15.4 14.7 16.1 11.0 13.1 9.7 12.1 11.4 10.8 11.8 13.3 14.0 14.1 10.0 11.0 18.5 13.1 10.3 10.9 17.0 11.2 18.3 12.9 11.4 10.1 15.1 10.5 10.8 11.5 12.3 11.2 12.6 9.5 11.2 16.0 35.3 11.3 11.3 17.7 11.9 12.4 11.8 13.8 12.5 10.9 10.1 10.3 14.5 12.8 11.8 16.6 15.9 7.4 12.8 17.2 14.6 10.8 8.9 21.0 7.3 12.3 7.6 7.9 16.2 14.8 12.8 12.6 10.2 16.0 10.9 17.3 16.0 13.2 9.9 12.1 12.0 10.1 12.9 7.9 14.9 12.5 26.8 14.5 19.5 14.1 7.0 10.1 13.6 16.1 11.1 20.4 17.4 12.9 17.8 11.5 10.9 14.1 15.7 14.1 11.9 18.1 7.6 15.9 12.2 16.0 12.5 8.8 12.4 7.4 7.5 11.4 16.7 11.5 13.3 20.5 25.7 34.7 28.9 15.6 14.7 21.8 2.8 11.5 7.4 14.5 12.8 14.6 16.6 12.7 13.6 14.2 13.8 12.9 12.5 3.2 17.2 11.1 15.9 11.2 10.8 10.1 15.4 11.0 13.1 13.1 10.3 12.9 11.4 12.3 12.5 RNASEH2A "AGS4, RNASEHI, RNHIA, RNHL" ENSG00000104889 "Ribonuclease H2 subunit A" O75792 19 12806556-12815201 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 44.8" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042692 Enhanced Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA042692: AB_10793981" "unprognostic (6.74e-2)" "prognostic favourable (1.18e-4)" "prognostic favourable (6.18e-4)" "unprognostic (2.24e-1)" "unprognostic (2.62e-1)" "unprognostic (5.13e-2)" "prognostic unfavourable (8.72e-5)" "unprognostic (8.48e-2)" "unprognostic (9.33e-2)" "prognostic favourable (1.22e-4)" "unprognostic (3.80e-3)" "unprognostic (8.71e-2)" "prognostic unfavourable (6.29e-6)" "unprognostic (3.40e-3)" "unprognostic (4.35e-2)" "unprognostic (5.35e-2)" "unprognostic (8.60e-2)" 6.5 5.5 6.4 11.4 10.6 21.9 6.6 11.0 7.5 6.8 6.6 9.2 1.6 8.6 6.8 4.4 14.1 6.0 5.7 5.1 6.7 4.8 8.7 5.9 5.5 9.2 10.6 5.8 7.3 7.0 6.2 4.1 11.8 6.1 5.3 5.7 5.5 8.8 4.3 7.1 13.4 7.1 4.4 7.8 12.0 7.4 14.1 8.4 44.8 8.6 13.4 17.4 6.0 8.0 11.3 7.8 7.1 6.8 12.9 8.6 5.0 14.8 11.2 6.8 6.8 1.0 1.9 8.4 6.9 2.9 10.4 12.1 8.8 5.7 15.9 10.5 1.6 8.9 5.5 6.8 5.7 8.6 15.0 7.6 11.9 6.8 0.7 7.0 7.1 1.0 1.7 8.8 3.2 4.0 10.5 4.7 4.9 25.5 12.8 6.9 6.7 19.6 13.8 9.8 11.4 2.6 5.9 14.1 8.2 7.5 2.7 3.1 7.4 4.3 3.8 12.4 6.2 17.6 11.4 11.5 12.7 12.6 7.3 11.2 10.0 7.1 6.8 6.4 8.6 6.6 7.0 9.8 7.0 6.1 4.2 11.3 6.6 6.5 6.8 12.9 5.9 7.8 5.5 5.0 6.4 10.6 11.0 7.5 6.7 4.8 10.6 5.8 6.1 8.4 RNGTT "hCAP, HCE, HCE1" ENSG00000111880 "RNA guanylyltransferase and 5'-phosphatase" O60942 6 88610272-88963721 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA capping, mRNA processing" "Hydrolase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003750 Approved Approved Nucleoplasm Nucleoplasm "HPA003750: AB_1856383" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (2.82e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-2)" "unprognostic (1.10e-1)" "prognostic unfavourable (1.37e-4)" "unprognostic (4.48e-3)" "unprognostic (1.28e-1)" "unprognostic (4.05e-3)" "unprognostic (3.76e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-3)" "unprognostic (9.83e-2)" "unprognostic (6.55e-2)" "unprognostic (1.67e-1)" "unprognostic (8.08e-3)" 9.1 12.1 10.2 19.6 12.2 14.2 9.9 18.5 13.1 10.0 8.1 8.7 7.0 7.4 11.1 7.2 12.5 8.7 7.2 9.6 10.5 16.0 9.4 11.8 9.4 26.3 9.8 6.4 10.4 6.6 12.1 23.1 11.6 11.1 9.8 9.8 9.4 8.4 11.6 10.5 9.0 10.7 10.7 10.7 14.3 7.5 15.0 10.4 28.0 10.0 7.8 28.2 10.9 13.8 18.6 4.4 5.7 4.6 8.0 8.4 4.3 5.6 8.6 13.5 17.1 7.9 8.4 8.1 12.9 8.5 10.5 13.3 9.8 4.3 14.6 10.6 9.2 7.1 15.7 10.4 19.4 19.8 12.3 19.0 7.8 7.8 6.5 20.3 10.8 5.3 9.2 10.9 10.6 9.3 18.7 11.8 15.6 7.5 8.9 14.5 8.1 7.6 17.7 20.9 8.3 9.4 8.8 7.9 11.4 10.7 6.5 7.0 7.0 20.4 7.3 8.5 7.9 9.6 17.4 10.7 18.7 8.2 12.5 15.2 15.5 3.5 3.0 5.7 6.4 4.6 6.4 18.6 7.2 7.9 4.4 16.8 8.2 8.4 2.5 8.0 3.9 3.1 6.7 4.3 10.2 12.2 18.5 13.1 10.5 16.0 9.8 6.4 11.1 10.4 RNPEP APB ENSG00000176393 "Arginyl aminopeptidase" Q9H4A4 1 201982372-202006147 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 12.1;granulocytes: 12.3;monocytes: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036074, HPA036075, HPA061487" Approved Supported "Nucleoplasm,Golgi apparatus" "Secreted - unknown location" 6600000 "Golgi apparatus" Nucleoplasm "HPA036074: AB_2674926, HPA036075: AB_10672999, HPA061487: " "unprognostic (8.57e-2)" "unprognostic (3.43e-2)" "unprognostic (2.81e-1)" "unprognostic (5.45e-2)" "unprognostic (2.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.95e-2)" "unprognostic (2.87e-2)" "unprognostic (1.93e-3)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (3.50e-3)" "unprognostic (1.91e-1)" "unprognostic (6.00e-2)" "unprognostic (1.97e-2)" "unprognostic (1.68e-1)" 18.5 22.0 6.4 14.9 8.2 9.5 16.7 9.2 11.0 17.8 34.2 13.5 21.2 31.1 17.4 18.7 33.2 19.2 21.8 11.5 6.1 4.6 22.5 18.3 21.5 14.1 7.0 5.4 18.0 19.5 11.6 10.4 26.3 9.0 18.4 26.8 16.4 25.1 13.6 10.0 18.3 66.6 12.8 8.1 22.7 15.7 21.2 6.0 13.9 28.4 19.1 24.7 17.6 17.5 2.3 12.1 12.3 17.0 1.6 3.1 2.2 19.0 20.7 12.3 18.5 20.2 19.0 31.1 14.7 28.5 18.4 20.8 14.8 24.4 4.1 18.9 25.8 34.6 15.7 28.7 12.9 11.3 20.3 10.4 9.9 13.9 17.2 26.4 36.8 17.3 29.7 16.4 18.9 33.1 23.6 6.2 18.6 17.4 3.6 11.2 17.4 10.3 13.9 17.4 29.4 38.3 17.3 14.3 12.1 36.3 45.4 14.6 34.5 15.1 23.6 8.7 11.7 8.4 17.8 13.8 11.1 3.7 8.6 22.5 17.3 10.8 9.2 12.3 1.9 15.7 2.6 1.6 2.0 2.2 12.1 2.3 1.8 2.1 6.7 1.6 17.0 4.5 3.1 2.2 6.4 8.2 9.2 11.0 6.1 4.6 7.0 5.4 9.0 6.0 RNPEPL1 ENSG00000142327 "Arginyl aminopeptidase like 1" Q9HAU8 2 240565804-240581372 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036772 Uncertain Approved Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA036772: AB_10670848" "unprognostic (3.92e-2)" "unprognostic (7.28e-2)" "unprognostic (1.20e-2)" "unprognostic (2.39e-1)" "unprognostic (5.24e-3)" "prognostic favourable (7.43e-4)" "prognostic unfavourable (5.06e-4)" "unprognostic (3.72e-3)" "unprognostic (9.10e-2)" "unprognostic (1.66e-3)" "unprognostic (3.10e-1)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (5.31e-2)" "unprognostic (9.86e-2)" 17.2 13.7 10.1 13.7 8.8 17.2 48.4 7.2 10.5 11.0 21.0 9.5 11.8 18.6 8.0 8.9 22.1 8.0 22.3 28.3 9.2 6.0 18.2 26.7 32.2 54.1 12.9 8.2 7.1 40.0 7.7 4.3 10.1 8.1 14.9 9.1 7.0 21.5 13.5 26.5 22.5 31.0 11.4 9.7 25.7 20.0 5.9 7.6 23.1 8.8 16.7 12.1 14.4 18.8 7.0 7.6 22.4 9.1 7.6 12.4 5.4 6.8 11.5 2.5 6.8 9.4 9.8 8.7 4.4 11.0 5.0 6.2 3.1 20.2 2.0 2.3 11.1 7.5 2.9 8.2 0.5 12.0 4.0 4.5 3.7 18.6 23.7 2.9 8.2 11.6 13.4 2.6 5.1 17.0 3.3 13.4 3.3 9.7 3.7 11.1 3.4 4.6 7.8 3.8 16.6 20.2 9.5 2.4 5.1 3.0 10.3 20.0 7.2 13.6 11.6 5.4 5.6 7.5 5.0 12.7 1.9 2.3 11.1 8.3 8.1 5.8 9.1 22.4 12.4 7.8 10.6 7.0 9.6 11.1 6.4 6.8 5.4 8.1 16.0 7.6 7.6 7.6 11.1 5.4 10.1 8.8 7.2 10.5 9.2 6.0 12.9 8.2 8.1 7.6 RPAP2 "C1orf82, FLJ13150, Rtr1" ENSG00000122484 "RNA polymerase II associated protein 2" Q8IXW5 1 92298965-92402056 "Enzymes, Predicted membrane proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046443 Approved Supported Nucleoli,Cytosol "Nucleoli, Cytosol" "HPA046443: " "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.71e-2)" "unprognostic (4.12e-2)" "unprognostic (4.96e-3)" "unprognostic (5.73e-2)" "unprognostic (1.23e-3)" "unprognostic (3.29e-2)" "unprognostic (8.01e-3)" "unprognostic (4.09e-2)" "unprognostic (2.59e-1)" "unprognostic (6.09e-2)" "unprognostic (7.02e-4)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.62e-3)" "unprognostic (4.10e-2)" 6.8 7.0 7.8 7.3 10.5 12.0 7.6 27.2 11.6 8.4 6.3 7.1 7.2 6.6 11.1 11.5 5.6 6.3 5.5 5.9 8.1 8.6 8.1 10.6 5.2 8.2 7.7 6.7 8.2 8.6 9.4 16.1 6.7 11.7 7.6 5.8 6.4 7.2 7.1 10.5 10.7 6.3 7.4 9.9 7.6 6.4 6.7 8.7 12.8 9.4 6.5 6.3 6.6 7.6 4.4 3.5 4.9 2.4 4.0 4.8 1.2 6.2 3.8 6.7 6.1 5.5 7.1 5.7 4.9 3.4 3.2 2.7 2.7 2.8 9.3 8.5 3.6 4.3 5.5 3.2 5.0 6.3 4.0 5.7 6.9 3.6 3.3 9.8 5.7 3.6 3.9 4.2 4.1 3.4 5.8 6.2 4.9 3.2 8.3 6.2 5.2 4.3 6.2 8.9 4.0 4.2 5.6 6.2 4.6 8.0 7.3 4.0 3.9 7.5 6.0 4.9 6.2 5.6 6.9 6.0 7.0 4.9 3.4 6.2 3.3 4.8 2.4 1.9 4.1 1.7 4.8 3.4 3.2 3.5 1.8 4.4 3.5 3.8 4.9 4.0 1.9 3.5 2.8 1.2 7.8 10.5 27.2 11.6 8.1 8.6 7.7 6.7 11.7 8.7 RPE65 "BCO3, LCA2, rd12, RP20" ENSG00000116745 "RPE65, retinoid isomerohydrolase" Q16518 1 68428822-68449959 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Hydrolase, Isomerase" "Disease mutation, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "retina: 268.3" "Cell line enhanced" "Detected in some" "A-431: 6.0;PC-3: 10.4;U-2 OS: 2.5" "Group enriched" "Detected in some" 10 "glioma: 5.8;head and neck cancer: 1.5" "Group enriched" "Detected in many" 5 "hypothalamus: 6.0;midbrain: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "unprognostic (1.59e-1)" "unprognostic (1.88e-1)" "unprognostic (3.15e-1)" "prognostic favourable (9.75e-4)" "unprognostic (4.55e-2)" "unprognostic (5.91e-2)" "unprognostic (6.59e-4)" "unprognostic (2.98e-2)" "unprognostic (1.57e-1)" "unprognostic (8.24e-2)" "unprognostic (3.21e-4)" "unprognostic (2.11e-1)" "unprognostic (2.05e-1)" "unprognostic (3.48e-2)" "unprognostic (8.40e-3)" 0.0 0.0 0.9 0.1 0.7 0.0 1.0 0.1 3.8 0.2 0.1 1.3 1.4 0.4 1.4 0.7 0.8 0.6 0.2 0.0 1.5 6.0 0.0 0.0 0.0 0.1 8.8 0.1 0.1 0.0 0.0 0.0 0.0 1.2 4.2 0.2 268.3 0.2 10.5 0.0 0.0 0.1 0.5 1.4 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.6 1.5 6.0 8.8 0.1 1.2 0.6 RPP14 P14 ENSG00000163684 "Ribonuclease P/MRP subunit p14" O95059 3 58306247-58324695 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 53.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036194 Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA036194: AB_10672082" "unprognostic (6.05e-2)" "unprognostic (2.02e-2)" "unprognostic (1.50e-3)" "unprognostic (1.36e-1)" "unprognostic (4.08e-3)" "unprognostic (2.51e-1)" "unprognostic (1.30e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (2.95e-3)" "unprognostic (3.76e-2)" "prognostic favourable (3.07e-10)" "unprognostic (5.19e-3)" "unprognostic (2.36e-1)" "prognostic unfavourable (2.96e-4)" "unprognostic (5.78e-2)" 7.1 8.5 8.3 5.7 12.9 5.3 7.1 15.8 10.7 6.6 8.6 5.9 6.6 10.2 8.2 7.8 8.5 7.4 6.2 11.8 7.2 6.8 11.2 15.0 5.6 7.6 6.5 9.9 8.4 11.9 10.8 9.4 6.0 7.2 7.4 8.2 9.0 8.5 7.0 53.5 7.4 9.1 11.7 5.5 7.7 7.7 9.1 5.9 6.3 8.1 18.5 8.5 7.2 7.0 4.6 6.6 4.7 9.8 9.8 6.4 3.5 10.1 8.0 9.4 7.4 7.8 8.4 10.3 8.6 9.2 12.3 13.9 12.2 6.7 12.1 2.0 11.5 6.2 14.0 12.7 12.0 8.4 7.4 11.5 9.6 6.6 7.7 19.8 9.6 9.2 12.3 14.6 14.0 9.7 9.9 8.7 11.9 5.5 13.4 7.0 12.3 15.3 5.5 7.4 11.7 9.0 14.5 5.9 10.4 8.0 9.6 11.5 9.2 9.6 8.8 9.3 10.4 9.8 16.2 13.0 22.2 17.5 10.7 13.9 6.6 3.0 5.7 4.7 4.2 4.9 5.6 4.1 5.5 5.8 6.6 4.6 6.4 6.2 2.6 9.8 9.8 6.2 3.0 3.5 8.3 12.9 15.8 10.7 7.2 6.8 6.5 9.9 7.2 5.9 RPP21 "C6orf135, Em:AB014085.3, FLJ22638" ENSG00000241370 "Ribonuclease P/MRP subunit p21" Q9H633 6 30345131-30346884 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 20.5;EFO-21: 22.0;HEK 293: 24.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (2.73e-1)" "unprognostic (1.09e-3)" "unprognostic (2.83e-1)" "unprognostic (4.65e-2)" "unprognostic (1.78e-1)" "unprognostic (6.46e-2)" "unprognostic (2.18e-2)" "unprognostic (8.37e-2)" "unprognostic (2.86e-1)" "unprognostic (1.65e-2)" "unprognostic (2.65e-2)" "unprognostic (2.76e-2)" "prognostic unfavourable (1.04e-5)" "unprognostic (9.54e-2)" "unprognostic (1.01e-2)" "unprognostic (4.13e-2)" "prognostic favourable (6.78e-5)" 21.9 30.8 16.5 12.4 20.3 10.0 16.7 14.6 21.4 19.4 20.5 10.7 11.0 13.5 20.1 11.4 38.6 26.2 12.6 16.2 13.1 14.6 15.9 16.7 8.3 13.2 13.6 11.7 22.1 27.7 4.1 11.2 10.7 12.5 19.1 3.3 10.2 11.3 16.1 32.5 45.9 15.4 27.4 12.3 11.8 22.8 9.8 10.9 12.3 19.1 8.9 15.6 19.2 16.6 20.1 11.5 11.1 13.1 6.7 17.7 9.6 17.4 0.0 0.0 20.5 8.0 5.7 9.7 4.5 4.0 6.1 6.4 0.3 0.0 13.0 22.0 2.2 0.1 0.0 9.4 1.5 6.1 24.1 9.6 0.0 2.3 15.2 0.0 0.0 1.6 1.3 0.2 1.1 0.0 3.0 5.5 2.4 0.9 0.0 0.7 15.2 0.0 5.4 0.0 0.6 8.5 8.5 19.9 2.3 0.0 4.4 11.2 0.0 0.6 0.3 0.0 0.0 14.6 0.1 4.9 12.4 5.7 0.0 1.2 0.0 11.1 13.1 8.4 6.6 11.5 9.1 20.1 11.7 6.9 11.5 16.8 14.1 8.0 4.0 6.7 12.5 4.6 17.7 9.6 16.5 20.3 14.6 21.4 13.1 14.6 13.6 11.7 12.5 10.9 RPP25 FLJ20374 ENSG00000178718 "Ribonuclease P and MRP subunit p25" Q9BUL9 15 74954416-74957464 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 18.6;SCLC-21H: 17.1;SK-MEL-30: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 16.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.7;monocytes: 6.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046900 Approved Supported "Nucleoplasm,Centriolar satellite" Nucleoplasm "Centriolar satellite" "HPA046900: AB_10962049" "unprognostic (9.36e-2)" "unprognostic (7.17e-3)" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "prognostic unfavourable (2.24e-5)" "unprognostic (7.18e-2)" "unprognostic (5.73e-3)" "unprognostic (5.50e-3)" "unprognostic (7.78e-2)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (4.71e-3)" "unprognostic (5.50e-3)" "unprognostic (5.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-1)" 3.9 7.3 3.0 1.9 4.6 0.0 2.2 3.2 14.0 3.4 6.7 3.7 1.2 6.0 1.7 1.3 3.3 1.8 3.7 2.5 2.5 6.8 2.6 1.9 5.1 2.7 8.0 5.1 12.0 4.9 9.0 2.8 6.1 10.6 2.1 4.1 3.2 2.4 1.3 1.9 2.1 4.6 2.0 7.9 6.2 5.6 1.9 1.8 3.1 4.9 2.6 2.5 4.1 2.4 2.3 16.7 0.3 6.4 0.3 2.7 1.4 8.9 6.8 1.7 0.0 0.6 0.4 2.9 1.7 2.0 0.5 0.4 9.2 8.2 0.0 7.8 1.7 2.7 5.3 0.3 0.1 3.3 0.2 0.0 7.9 0.2 18.6 0.0 5.3 2.4 0.2 3.4 0.0 7.9 6.0 0.0 1.7 3.4 1.4 2.3 8.2 2.7 0.0 0.0 6.0 1.6 0.1 17.1 12.8 12.8 11.3 25.5 2.2 7.1 1.8 0.0 0.7 1.6 0.0 0.1 0.0 0.0 0.9 13.9 10.0 0.0 3.3 0.0 1.5 6.4 0.9 2.3 1.1 1.3 3.3 1.9 2.7 2.1 0.3 0.3 4.8 16.7 0.4 1.4 3.0 4.6 3.2 14.0 2.5 6.8 8.0 5.1 10.6 1.8 RPP30 TSG15 ENSG00000148688 "Ribonuclease P/MRP subunit p30" P78346 10 90871716-90908553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037578 Approved Approved "Nucleoplasm,Nucleoli,Microtubule ends,Cytosol" "Nucleoplasm, Nucleoli" "Microtubule ends, Cytosol" "HPA037578: AB_10696939" "unprognostic (1.55e-1)" "unprognostic (1.77e-3)" "unprognostic (2.35e-1)" "unprognostic (4.08e-1)" "unprognostic (5.64e-2)" "unprognostic (3.05e-2)" "unprognostic (3.80e-3)" "unprognostic (1.27e-1)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (2.27e-2)" "unprognostic (2.65e-1)" "prognostic unfavourable (1.01e-6)" "unprognostic (1.98e-1)" "unprognostic (9.84e-3)" "unprognostic (3.43e-2)" "unprognostic (2.10e-2)" 24.2 19.0 20.9 16.8 20.3 27.2 22.3 26.0 24.0 18.9 19.0 16.2 16.3 11.5 25.2 18.6 23.8 19.2 16.0 26.6 19.8 16.8 20.6 18.4 17.1 23.2 18.5 20.4 23.9 17.7 37.7 23.6 23.6 19.3 18.8 19.3 18.7 19.2 16.5 35.9 23.5 16.4 20.6 19.2 21.3 19.2 32.0 21.6 31.2 18.1 24.0 26.3 21.7 18.9 19.4 22.2 16.2 19.5 14.2 20.3 16.2 28.0 18.7 19.6 23.6 12.8 13.8 6.9 20.1 18.1 33.7 35.4 31.6 22.6 16.6 15.4 12.8 19.7 26.1 17.8 34.7 26.6 18.0 11.1 12.0 24.9 12.1 22.5 14.1 11.3 11.6 25.3 28.8 19.1 22.1 15.2 22.2 17.3 26.1 30.7 12.1 21.3 14.6 16.7 17.4 12.7 13.3 10.6 10.7 11.7 8.5 23.6 23.0 14.3 10.8 16.8 16.8 9.5 41.4 10.3 26.3 35.6 21.1 12.2 12.9 4.3 19.5 16.2 17.1 18.7 18.6 19.4 19.6 18.7 22.2 16.7 17.0 18.5 2.2 14.2 15.3 20.7 20.3 16.2 20.9 20.3 26.0 24.0 19.8 16.8 18.5 20.4 19.3 21.6 RPP38 ENSG00000152464 "Ribonuclease P/MRP subunit p38" P78345 10 15097180-15139818 "Enzymes, Predicted intracellular proteins, Ribosomal proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045128, HPA050398" Approved Supported Nucleoli Nucleoli "HPA045128: , HPA050398: " "unprognostic (1.75e-1)" "unprognostic (3.91e-2)" "unprognostic (3.76e-2)" "unprognostic (1.51e-1)" "unprognostic (9.93e-2)" "unprognostic (1.17e-1)" "prognostic unfavourable (1.46e-4)" "unprognostic (1.41e-2)" "unprognostic (4.86e-1)" "unprognostic (1.57e-3)" "unprognostic (3.42e-1)" "unprognostic (7.21e-2)" "prognostic unfavourable (6.25e-4)" "unprognostic (6.13e-2)" "unprognostic (1.95e-1)" "unprognostic (5.11e-2)" "prognostic favourable (2.89e-6)" 13.1 12.2 12.4 10.7 13.6 9.7 18.3 22.4 12.4 13.6 16.7 12.0 15.8 14.4 15.7 16.1 15.2 18.2 10.3 10.0 11.6 10.2 17.4 21.6 12.5 16.3 15.0 10.0 14.4 16.8 11.3 16.0 17.4 12.7 18.4 15.7 11.7 17.1 14.9 20.9 14.8 17.9 14.3 11.5 16.7 13.5 38.6 12.7 18.8 19.8 13.9 18.5 13.4 13.6 31.0 25.7 23.4 24.5 18.6 31.4 20.2 20.9 15.9 8.7 11.2 11.8 12.2 15.4 10.2 7.7 16.0 16.5 16.0 22.1 17.6 11.0 9.5 19.7 17.5 17.7 14.8 13.4 15.9 18.1 9.7 14.0 25.4 10.2 15.3 14.5 24.5 13.1 11.6 12.8 20.9 12.6 12.2 17.3 18.2 11.2 10.1 7.8 15.0 8.8 21.9 20.5 8.3 8.3 10.5 14.1 24.5 28.2 21.9 16.5 11.0 7.4 12.9 15.6 13.4 17.5 18.7 24.0 14.5 12.5 7.0 8.5 24.5 23.4 25.6 23.7 25.1 28.8 26.2 31.4 25.3 31.0 30.6 27.8 8.3 18.6 18.6 25.7 22.0 20.2 12.4 13.6 22.4 12.4 11.6 10.2 15.0 10.0 12.7 12.7 RPP40 "bA428J1.3, RNASEP1" ENSG00000124787 "Ribonuclease P/MRP subunit p40" O75818 6 4994732-5004063 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035685, HPA035686" Uncertain Approved Nucleoplasm Nucleoplasm "HPA035685: , HPA035686: AB_10670153" "unprognostic (2.93e-2)" "unprognostic (3.22e-2)" "unprognostic (1.94e-1)" "prognostic unfavourable (6.10e-6)" "unprognostic (8.00e-2)" "unprognostic (4.78e-2)" "prognostic unfavourable (5.41e-4)" "unprognostic (1.20e-1)" "unprognostic (1.72e-2)" "unprognostic (6.44e-2)" "unprognostic (8.17e-2)" "unprognostic (9.57e-2)" "prognostic unfavourable (7.54e-8)" "unprognostic (1.54e-1)" "unprognostic (5.10e-1)" "unprognostic (4.08e-2)" "unprognostic (2.19e-1)" 6.9 16.8 10.8 7.2 10.7 6.7 11.1 3.5 11.9 6.0 5.5 4.2 6.3 4.6 6.1 6.6 11.9 5.5 4.7 5.5 10.0 8.8 5.6 10.8 3.9 10.1 9.9 5.8 6.2 7.8 5.2 8.6 5.6 9.1 5.3 5.3 1.5 4.0 6.7 7.7 9.8 3.6 7.5 5.3 6.8 4.3 10.5 8.0 6.1 5.6 13.0 8.3 9.1 6.9 7.8 12.3 0.0 11.1 7.9 8.4 5.0 6.4 10.7 3.4 9.6 6.3 8.1 10.8 6.3 3.2 12.1 9.7 14.5 4.9 13.9 28.1 6.6 6.8 7.0 9.8 11.1 5.2 14.0 8.7 7.0 19.7 7.4 11.2 5.0 6.3 8.4 12.1 12.1 11.9 13.7 2.8 8.8 18.2 5.6 19.3 5.6 17.5 12.1 6.4 25.4 6.2 7.0 12.2 3.5 5.9 5.7 6.3 10.4 9.3 5.6 16.1 10.8 10.8 14.4 5.0 20.9 10.9 3.0 18.8 8.2 0.0 6.9 0.0 3.4 11.1 5.0 7.8 5.9 4.1 12.3 6.5 8.1 7.2 0.0 7.9 3.5 5.9 8.4 5.0 10.8 10.7 3.5 11.9 10.0 8.8 9.9 5.8 9.1 8.0 RTEL1 "bK3184A7.3, C20orf41, DKFZP434C013, KIAA1088, NHL, RTEL" ENSG00000258366 "Regulator of telomere elongation helicase 1" Q9NZ71 20 63657810-63696253 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Disease mutation, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "HPA020622, HPA067329, HPA078328" Approved "Nuclear speckles,Nuclear bodies" "Nuclear speckles, Nuclear bodies" "HPA020622: , HPA067329: , HPA078328: " "unprognostic (3.63e-2)" "unprognostic (8.08e-3)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.27e-1)" "unprognostic (9.30e-3)" "unprognostic (2.59e-1)" "unprognostic (3.64e-2)" "unprognostic (3.30e-2)" "unprognostic (9.05e-2)" "unprognostic (4.09e-2)" "unprognostic (9.50e-2)" "unprognostic (8.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" "unprognostic (8.84e-2)" 8.4 14.3 9.4 11.5 12.4 14.2 7.9 25.6 11.8 9.1 11.1 11.2 10.9 9.8 15.4 7.4 7.0 9.5 9.3 6.2 8.0 6.9 7.1 7.2 8.9 7.8 7.5 12.1 10.6 17.8 7.2 18.2 9.8 8.2 10.2 4.8 10.2 12.9 10.2 10.2 8.2 10.1 8.8 4.4 11.6 10.4 17.6 8.9 9.1 11.9 4.9 9.5 9.3 9.0 1.7 3.6 0.0 3.3 0.4 3.0 2.4 5.2 7.2 5.2 10.0 1.1 1.2 9.6 10.9 2.9 17.0 4.5 14.4 4.5 7.1 5.7 3.3 9.9 3.5 7.1 4.1 3.5 7.3 8.7 12.5 13.7 3.8 8.5 16.0 1.5 4.0 4.2 5.2 5.8 10.8 6.7 3.8 5.6 13.2 11.0 5.1 15.2 10.6 4.9 7.3 2.7 6.5 10.3 6.2 6.1 17.8 1.3 4.7 9.6 7.7 19.3 6.3 6.6 8.3 6.2 2.6 4.4 4.7 6.0 6.7 0.0 2.7 0.0 3.0 3.3 1.6 0.9 1.7 2.0 3.6 1.7 2.9 1.1 0.0 0.4 2.6 3.2 1.4 2.4 9.4 12.4 25.6 11.8 8.0 6.9 7.5 12.1 8.2 8.9 RUVBL1 "ECP54, INO80H, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49a" ENSG00000175792 "RuvB like AAA ATPase 1" Q9Y265 3 128064778-128153914 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Growth regulation, Mitosis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019947, HPA019948" Enhanced Supported Nucleoplasm,Cytosol 47000 "Nucleoplasm, Cytosol" "HPA019947: AB_1856516, HPA019948: AB_1856514" "unprognostic (7.40e-2)" "unprognostic (2.17e-1)" "unprognostic (1.28e-1)" "unprognostic (4.73e-2)" "unprognostic (3.55e-1)" "unprognostic (2.66e-2)" "prognostic unfavourable (1.21e-8)" "unprognostic (2.43e-2)" "unprognostic (3.31e-2)" "unprognostic (1.39e-1)" "unprognostic (2.25e-2)" "unprognostic (7.39e-2)" "unprognostic (2.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (1.61e-1)" "unprognostic (9.27e-2)" 17.6 15.1 10.7 15.8 14.2 11.9 13.9 7.9 14.0 12.5 11.6 12.9 14.3 8.4 19.2 11.4 19.2 37.3 11.3 18.6 11.4 13.6 20.9 13.7 12.9 18.7 10.0 9.8 15.4 13.6 26.5 14.2 19.9 13.0 12.0 14.1 11.5 10.2 12.0 12.9 11.8 10.2 16.1 8.8 21.9 10.9 44.7 10.3 33.4 15.2 18.1 23.9 12.6 15.0 10.6 8.7 1.5 7.9 10.9 20.2 7.2 26.7 24.3 14.9 24.3 11.7 11.4 19.6 13.1 11.3 25.3 17.5 25.4 15.9 38.0 13.1 12.5 21.3 39.8 27.8 29.5 15.5 19.5 31.5 14.1 17.0 12.1 29.4 10.1 11.6 14.7 21.3 27.4 16.9 25.8 8.9 14.4 38.1 31.5 22.3 37.6 20.8 25.9 18.1 26.4 15.1 10.1 25.1 22.5 14.5 12.0 20.1 21.8 21.8 10.9 11.5 14.1 17.3 19.8 9.1 14.5 37.3 14.2 18.1 14.4 0.8 4.8 1.5 11.3 7.9 14.6 10.6 13.6 14.0 7.7 10.2 11.5 12.8 0.2 10.9 7.4 8.7 20.2 7.2 10.7 14.2 7.9 14.0 11.4 13.6 10.0 9.8 13.0 10.3 RUVBL2 "ECP51, INO80J, Reptin52, RVB2, TIH2, TIP48, TIP49b" ENSG00000183207 "RuvB like AAA ATPase 2" Q9Y230 19 48993448-49015995 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 59.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012432, HPA042880, HPA067966" Enhanced Supported Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Cytosol" Centrosome "CAB012432: , HPA042880: AB_2678210, HPA067966: AB_2685933" "unprognostic (1.71e-1)" "unprognostic (9.06e-3)" "unprognostic (3.51e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (2.47e-2)" "prognostic unfavourable (9.28e-4)" "unprognostic (7.06e-3)" "unprognostic (6.25e-2)" "unprognostic (3.28e-1)" "unprognostic (8.13e-2)" "unprognostic (7.58e-2)" "unprognostic (2.81e-2)" "unprognostic (2.21e-2)" "unprognostic (7.61e-3)" "unprognostic (1.61e-1)" "unprognostic (2.58e-1)" 6.9 5.3 6.7 7.5 7.1 13.4 4.8 8.2 10.4 4.8 9.9 7.6 6.3 11.2 8.3 5.5 16.1 5.5 7.2 9.1 6.9 6.0 7.6 10.3 5.5 8.2 7.7 8.1 6.5 8.7 1.6 6.4 5.5 6.7 6.0 3.2 6.5 10.0 6.6 27.8 7.7 10.0 3.7 7.1 6.9 10.7 59.0 5.8 14.6 8.8 9.4 8.1 6.4 12.9 12.6 16.4 5.6 14.3 11.0 12.5 15.2 28.8 29.7 3.5 20.0 1.5 2.7 9.4 15.6 6.8 17.9 11.8 15.4 12.5 27.1 12.1 3.1 15.3 2.1 10.2 2.1 16.4 12.2 17.7 8.9 7.8 5.0 34.7 12.4 3.1 2.0 4.0 2.1 6.6 30.6 11.5 1.6 5.9 30.6 4.1 10.7 4.4 25.4 16.0 17.4 3.2 11.1 14.2 20.5 15.7 13.1 5.6 11.6 13.3 9.7 11.4 16.7 7.5 38.6 23.4 26.7 28.0 8.4 17.0 16.3 5.6 14.3 4.2 11.1 11.1 11.2 10.9 11.1 9.1 16.4 12.6 12.2 8.0 1.0 11.0 10.8 12.5 12.5 15.2 6.7 7.1 8.2 10.4 6.9 6.0 7.7 8.1 6.7 5.8 SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716716 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" 7400000 "Nuclear membrane" "Golgi apparatus" "HPA047533: " "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favourable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavourable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favourable (2.95e-4)" "unprognostic (7.89e-2)" 65.5 43.6 18.7 23.3 17.3 36.4 42.6 11.2 15.5 44.4 38.5 23.0 38.8 20.7 41.8 57.9 40.3 27.3 33.2 30.8 18.7 18.4 56.5 68.2 44.7 41.1 24.7 12.6 55.7 70.9 21.2 41.7 46.0 18.4 44.4 28.0 28.5 43.5 36.2 51.9 23.3 33.3 39.7 31.5 38.4 29.5 28.2 19.7 33.2 74.6 39.3 32.1 49.8 37.8 29.1 44.3 32.6 48.4 34.3 45.9 46.3 23.6 51.1 37.7 58.3 47.8 59.7 29.0 37.8 44.1 31.1 37.2 54.7 58.7 11.8 24.9 46.5 51.6 52.3 31.7 33.8 28.9 38.6 34.3 58.2 51.3 41.5 25.8 38.9 41.1 39.9 21.4 34.8 43.9 34.1 31.6 41.9 55.5 10.5 56.1 40.1 22.0 13.2 48.8 38.3 69.8 66.3 18.5 41.6 31.4 35.2 85.1 34.4 60.0 29.9 31.5 23.7 26.9 46.0 31.1 58.9 16.6 34.2 45.5 24.6 20.7 43.8 24.1 28.4 47.3 28.5 29.1 35.4 30.4 43.8 26.6 30.2 30.9 32.6 34.3 48.4 44.3 45.9 46.3 18.7 17.3 11.2 15.5 18.7 18.4 24.7 12.6 18.4 19.7 SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139477-59158836 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 132.6" "Cell line enhanced" "Detected in many" "HDLM-2: 58.2;Karpas-707: 62.8;RPMI-8226: 127.1;U-266/70: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" "Nuclear membrane" "Golgi apparatus" "HPA026816: AB_10602089, HPA047533: " "unprognostic (1.47e-2)" "unprognostic (2.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.44e-2)" "unprognostic (3.13e-3)" "unprognostic (4.48e-3)" "unprognostic (2.95e-1)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.80e-2)" "unprognostic (1.72e-1)" "unprognostic (6.25e-2)" "unprognostic (3.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" 5.9 18.4 30.1 18.6 29.7 11.3 16.0 14.9 25.2 12.2 18.7 24.4 27.8 27.5 9.1 58.0 10.7 9.2 11.1 7.2 27.7 33.9 19.0 66.8 13.0 22.0 41.8 21.3 7.0 96.8 14.6 46.6 8.1 27.1 48.8 16.4 10.0 132.6 34.1 4.3 7.9 21.1 6.6 51.3 23.6 28.4 6.4 25.3 7.3 35.9 8.6 23.4 18.9 5.9 33.6 50.0 10.6 17.6 17.3 34.4 32.6 8.6 10.4 5.7 8.8 3.5 0.6 7.3 7.9 6.7 9.7 5.9 7.3 4.7 19.9 12.4 4.7 9.3 8.9 5.9 5.6 58.2 12.2 6.4 7.3 22.4 10.6 21.0 9.7 2.0 14.1 6.0 16.2 3.2 7.3 62.8 3.4 10.2 8.6 8.4 5.7 6.4 7.9 5.6 127.1 6.3 7.3 26.6 10.5 4.7 19.1 26.6 8.6 15.5 2.5 11.8 4.9 4.1 9.4 64.0 47.1 19.5 11.7 14.3 14.4 10.6 13.1 9.4 25.9 15.5 33.1 33.6 27.3 25.2 13.5 17.4 14.3 19.5 2.0 17.3 17.6 50.0 34.4 32.6 30.1 29.7 14.9 25.2 27.7 33.9 41.8 21.3 27.1 25.3 SGSH "HSS, MPS3A, SFMD" ENSG00000181523 "N-sulfoglucosamine sulfohydrolase" P51688 17 80206716-80220923 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 27.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023436, HPA023451" Enhanced "Intracellular and membrane" "HPA023436: AB_1856806, HPA023451: AB_1856807" "unprognostic (4.33e-2)" "unprognostic (4.03e-2)" "unprognostic (1.06e-2)" "unprognostic (4.01e-2)" "unprognostic (4.26e-3)" "unprognostic (1.39e-3)" "prognostic unfavourable (7.71e-4)" "prognostic favourable (2.72e-4)" "unprognostic (6.08e-2)" "unprognostic (3.65e-1)" "prognostic favourable (3.10e-4)" "unprognostic (2.05e-1)" "prognostic unfavourable (2.66e-4)" "unprognostic (1.42e-2)" "prognostic unfavourable (5.37e-4)" "unprognostic (7.50e-2)" "unprognostic (3.68e-2)" 14.4 37.1 7.8 11.6 7.5 2.3 13.5 5.5 7.3 12.0 11.2 9.3 16.5 8.5 13.8 14.8 11.2 13.2 14.2 8.5 7.9 9.3 16.3 9.9 15.1 19.9 5.5 6.7 11.3 19.5 16.5 13.8 19.2 7.7 17.2 5.8 18.1 18.8 19.5 6.1 14.9 12.3 11.2 6.8 23.3 13.2 8.1 6.7 3.6 16.6 11.4 16.1 14.5 8.9 3.9 16.0 1.8 16.1 6.4 14.4 9.5 1.2 3.7 3.2 6.6 9.2 8.3 4.7 8.2 16.2 11.4 10.4 3.2 4.2 0.0 13.4 7.0 4.0 2.0 3.4 2.1 3.9 5.1 0.0 9.2 9.2 27.9 0.0 2.9 15.8 4.2 3.3 4.4 22.4 3.5 9.3 6.1 6.4 0.1 0.1 2.0 6.5 0.5 1.7 9.6 7.1 6.4 0.9 6.6 9.2 17.2 4.4 15.4 0.2 15.4 13.3 3.8 5.0 2.9 15.4 1.8 1.6 6.1 0.0 6.5 0.0 16.1 0.0 10.9 6.8 14.4 3.1 9.2 10.8 16.0 3.9 7.5 6.3 1.8 6.4 6.0 1.1 10.9 9.5 7.8 7.5 5.5 7.3 7.9 9.3 5.5 6.7 7.7 6.7 SI ENSG00000090402 Sucrase-isomaltase P14410 3 164978898-165078495 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 123 "intestine: 181.4" "Cell line enhanced" "Detected in some" "BEWO: 2.8;CACO-2: 4.0;HeLa: 3.1;NB-4: 3.3;RPMI-8226: 4.8;SH-SY5Y: 2.9" "Cancer enhanced" "Detected in some" "stomach cancer: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011897 Enhanced "HPA011897: AB_1856840" "unprognostic (2.71e-2)" "unprognostic (1.62e-2)" "unprognostic (2.68e-1)" "unprognostic (2.05e-1)" "unprognostic (4.41e-2)" 0.1 0.1 0.1 1.4 0.1 0.0 0.1 0.1 0.1 0.1 93.3 0.0 0.0 94.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 5.4 0.0 0.1 0.0 0.1 0.1 181.4 0.0 0.1 0.1 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 32.6;ASC TERT1: 33.9;HSkMC: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" 1800000 "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favourable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favourable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 9.0 12.3 9.0 6.7 13.4 1.9 8.2 8.2 16.8 7.0 46.7 15.7 7.3 16.8 5.9 17.8 10.2 9.9 8.4 23.0 10.3 17.6 42.5 28.3 10.7 2.8 18.2 8.1 5.1 11.2 32.4 13.1 7.8 31.4 10.7 51.7 9.9 15.9 8.3 17.3 6.7 25.5 5.4 19.9 7.9 9.3 5.6 8.1 1.9 46.1 11.1 7.0 9.8 4.7 2.7 4.1 8.6 5.8 1.2 4.3 3.2 3.1 4.9 2.9 12.5 32.6 33.9 7.6 6.0 8.5 1.5 0.9 3.7 21.7 1.9 8.8 7.5 6.1 4.5 6.6 1.5 9.0 1.4 3.0 1.5 3.9 15.4 0.5 2.7 36.3 9.0 4.1 6.2 10.8 2.4 13.5 5.2 5.7 0.2 1.4 1.8 10.2 1.1 0.1 3.3 18.6 4.4 1.0 1.9 16.3 6.7 2.8 13.1 2.9 12.0 8.7 1.6 9.6 1.4 3.6 2.6 0.4 3.1 1.6 3.5 8.6 5.6 0.3 1.9 4.2 2.2 2.4 3.1 2.0 4.1 2.7 4.3 3.4 1.2 1.2 5.8 2.5 2.2 3.2 9.0 13.4 8.2 16.8 10.3 17.6 18.2 8.1 31.4 8.1 SMARCAD1 "DKFZP762K2015, ETL1, KIAA1122" ENSG00000163104 "SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1" Q9H4L7 4 94207611-94291292 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016737 Approved Enhanced Nucleoplasm Nucleoplasm "HPA016737: AB_1857271" "unprognostic (5.01e-2)" "unprognostic (5.83e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (8.41e-3)" "unprognostic (9.08e-3)" "prognostic unfavourable (3.22e-5)" "unprognostic (2.45e-1)" "unprognostic (3.49e-3)" "unprognostic (3.55e-1)" "unprognostic (2.57e-2)" "unprognostic (7.72e-2)" "unprognostic (2.99e-2)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (3.20e-3)" 12.8 15.4 15.4 22.2 14.6 8.6 20.1 26.7 25.1 15.4 13.6 9.4 14.4 12.6 19.6 17.5 17.2 16.5 13.9 12.9 13.6 14.7 16.6 14.9 21.6 22.8 17.6 11.1 20.8 15.0 17.2 33.0 18.3 14.9 15.4 16.5 10.2 14.9 20.9 11.8 26.5 13.9 15.6 17.9 17.6 13.9 15.3 16.2 42.0 20.2 11.4 17.8 16.0 15.9 5.5 4.3 3.5 3.0 7.5 6.2 2.7 7.3 9.6 29.7 19.4 8.6 14.1 15.4 13.1 12.3 11.0 10.5 8.5 12.0 18.9 9.1 11.2 6.4 20.9 11.1 15.9 14.4 9.5 13.6 10.3 13.1 12.4 19.8 14.6 14.4 9.1 13.6 17.6 17.0 22.4 7.9 16.6 5.8 33.6 10.5 20.6 4.7 19.6 17.0 9.6 12.8 9.0 17.5 25.8 10.1 17.0 14.4 8.7 13.4 16.1 14.3 15.3 8.7 10.0 11.1 16.7 22.7 13.4 10.6 17.6 3.5 2.5 0.3 4.6 3.0 4.8 5.5 5.1 4.9 4.3 4.2 5.5 6.2 0.0 7.5 2.9 3.7 4.1 2.7 15.4 14.6 26.7 25.1 13.6 14.7 17.6 11.1 14.9 16.2 SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390431-6394998 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease mutation, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 41.6;fHDF/TERT166: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" 2000000 "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (6.99e-2)" "unprognostic (2.28e-3)" "prognostic unfavourable (7.72e-5)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (4.90e-2)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "prognostic favourable (7.47e-4)" "unprognostic (4.35e-2)" "prognostic favourable (4.57e-6)" "unprognostic (4.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" 14.7 21.4 12.4 10.9 18.7 5.4 10.7 17.2 32.4 14.5 17.4 30.6 15.7 14.3 12.2 15.0 11.6 7.9 18.5 26.8 14.5 13.2 47.1 77.5 17.1 10.7 17.4 15.9 12.9 19.9 35.4 23.8 23.1 21.6 17.6 12.9 23.3 21.5 18.5 20.9 19.7 15.8 14.9 17.8 11.7 13.3 7.4 14.1 18.8 20.2 10.3 11.8 12.5 11.4 3.2 1.8 3.4 2.7 6.8 11.4 3.1 4.6 3.7 2.8 7.6 41.6 21.7 5.1 17.6 27.3 8.0 9.7 6.4 3.3 1.2 8.2 41.0 1.9 2.4 3.6 3.8 5.9 2.8 1.4 6.0 1.7 18.6 1.0 11.0 28.6 6.9 7.4 5.0 17.6 2.5 8.8 17.1 4.8 0.0 1.8 1.1 6.6 0.3 1.6 1.9 6.9 1.7 4.9 2.8 7.9 5.5 10.8 2.1 1.9 15.3 29.9 3.2 17.3 4.2 11.3 12.1 1.0 27.7 3.0 13.4 1.8 2.7 3.4 6.9 2.1 5.6 1.6 5.9 5.5 1.4 3.2 11.3 11.4 2.7 6.8 0.6 1.8 4.8 3.1 12.4 18.7 17.2 32.4 14.5 13.2 17.4 15.9 21.6 14.1 SMPD2 "ISC1, nSMase" ENSG00000135587 "Sphingomyelin phosphodiesterase 2" O60906 6 109440763-109443919 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA018110, HPA018125" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" "Vesicles, Plasma membrane" "Cell Junctions" "HPA018110: AB_1857292, HPA018125: AB_1857293" "unprognostic (1.61e-1)" "unprognostic (8.01e-2)" "unprognostic (1.97e-1)" "unprognostic (8.79e-3)" "unprognostic (3.88e-2)" "unprognostic (2.38e-1)" "prognostic unfavourable (1.17e-4)" "unprognostic (7.08e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" "prognostic favourable (1.00e-3)" "unprognostic (3.60e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" "unprognostic (1.45e-2)" "prognostic favourable (1.70e-4)" 6.0 6.8 4.2 20.2 4.9 8.5 8.5 5.4 6.4 9.0 12.6 9.8 16.4 10.5 6.1 16.0 17.2 17.4 12.6 5.1 4.9 3.7 10.2 7.8 8.4 9.4 4.7 4.2 6.7 15.5 17.9 8.8 19.5 4.8 10.1 10.2 8.4 16.6 11.9 3.3 16.9 15.4 7.8 4.3 10.1 11.1 35.1 4.7 18.3 10.5 13.5 23.0 6.3 10.1 18.3 13.4 9.3 7.8 6.2 8.0 5.3 8.9 10.4 5.5 8.6 9.6 5.3 18.3 3.0 11.1 7.5 7.2 9.7 7.3 4.9 6.4 6.4 11.5 5.5 13.2 4.5 6.2 14.2 5.7 10.7 6.0 8.1 6.2 6.7 5.6 15.3 6.7 13.3 6.9 10.9 8.7 3.7 12.9 10.0 13.5 1.5 5.0 7.0 2.6 5.3 13.7 15.3 7.2 6.0 5.7 17.8 13.4 5.7 11.9 4.4 3.4 4.9 2.7 11.2 5.9 1.5 3.1 6.6 5.9 6.0 5.7 7.8 9.3 6.6 7.5 7.3 12.8 7.4 8.0 10.2 18.3 5.6 5.7 2.3 6.2 6.6 13.4 7.2 5.3 4.2 4.9 5.4 6.4 4.9 3.7 4.7 4.2 4.8 4.7 SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358325-68448688 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 44.5;intestine: 46.4;lymphoid tissue: 73.0" "Cell line enhanced" "Detected in some" "HMC-1: 9.4;MOLT-4: 13.4;RPMI-8226: 11.1;SCLC-21H: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 7 "plasmacytoid DC: 44.5" "Lineage enriched" "Detected in many" 7 "dendritic cells: 44.5" "Region enhanced" "Detected in many" "basal ganglia: 103.1" "Low region specificity" "Detected in all" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favourable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favourable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" 3.5 2.3 6.0 3.1 18.3 1.8 1.6 9.4 15.4 1.0 9.6 2.5 0.0 46.4 1.7 0.7 1.8 2.7 17.2 1.2 8.7 3.6 0.9 3.8 2.1 3.5 2.5 5.0 2.7 1.9 0.7 10.7 0.8 3.9 2.2 5.8 4.3 2.2 0.9 1.8 8.1 42.7 1.2 1.4 3.0 18.6 4.2 4.4 73.0 1.3 1.3 4.3 1.6 1.2 0.6 44.5 6.1 0.0 0.0 0.7 0.3 0.3 0.7 0.3 0.1 0.0 0.0 5.2 0.4 0.0 0.4 0.1 2.9 0.9 0.4 0.5 0.2 1.1 0.0 0.0 0.1 0.3 0.7 0.1 2.1 0.3 0.0 0.0 9.4 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.3 0.2 13.4 2.5 0.6 0.1 0.6 0.2 11.1 0.0 0.1 12.9 2.5 0.4 1.5 0.6 1.0 0.8 0.0 0.4 0.8 1.4 0.1 2.1 1.1 0.2 0.2 0.8 0.2 1.0 0.0 6.1 0.7 0.0 0.1 0.6 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 44.5 0.5 0.3 6.0 18.3 9.4 15.4 8.7 3.6 2.5 5.0 3.9 4.4 SMPD4 "FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3" ENSG00000136699 "Sphingomyelin phosphodiesterase 4" Q9NXE4 2 130151392-130182750 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046279, HPA049426" Approved Approved "Nuclear membrane,Cytosol" "Nuclear membrane" Cytosol "HPA046279: , HPA049426: " "unprognostic (5.02e-2)" "unprognostic (9.61e-3)" "unprognostic (6.31e-2)" "prognostic unfavourable (7.47e-5)" "unprognostic (1.69e-1)" "unprognostic (8.80e-2)" "prognostic unfavourable (8.37e-6)" "unprognostic (3.27e-2)" "unprognostic (1.72e-1)" "unprognostic (7.47e-2)" "unprognostic (1.49e-2)" "prognostic unfavourable (1.73e-4)" "prognostic unfavourable (8.16e-8)" "unprognostic (1.74e-1)" "unprognostic (2.28e-1)" "unprognostic (1.47e-3)" "unprognostic (2.09e-1)" 13.2 16.1 12.4 17.1 20.7 39.1 14.8 22.1 25.1 19.9 15.8 31.4 15.3 15.5 22.5 14.1 19.3 19.5 12.7 13.4 13.2 16.0 14.3 18.5 14.7 20.5 21.3 12.2 22.2 22.2 24.1 31.2 24.3 19.5 16.3 16.7 17.7 17.1 15.2 17.0 17.5 15.2 18.3 16.0 16.4 14.5 23.6 21.6 27.9 22.8 19.6 27.1 16.9 16.6 10.5 9.8 14.5 11.4 11.7 15.2 9.7 31.7 15.7 19.8 14.6 10.2 7.5 25.8 16.9 12.6 25.0 20.9 45.4 16.3 20.7 15.0 17.0 18.1 25.3 22.4 17.4 27.4 24.4 23.3 16.9 36.0 8.7 26.0 14.9 8.8 15.0 28.0 11.2 14.4 28.9 16.8 13.9 17.2 27.1 13.1 30.4 20.9 28.8 15.1 22.5 10.6 15.1 27.6 15.4 16.7 20.4 7.4 13.9 11.4 11.1 21.4 20.8 14.0 19.8 14.7 16.4 27.8 19.3 14.9 15.2 1.8 9.3 14.5 13.9 11.4 15.2 9.5 10.4 12.4 9.8 10.5 10.2 11.4 4.5 11.7 8.0 6.4 9.4 9.7 12.4 20.7 22.1 25.1 13.2 16.0 21.3 12.2 19.5 21.6 SNRNP200 "ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD" ENSG00000144028 "Small nuclear ribonucleoprotein U5 subunit 200" O75643 2 96274336-96305515 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029321 Approved Supported Nucleoplasm 6600 Nucleoplasm "HPA029321: AB_10604096" "unprognostic (2.63e-2)" "unprognostic (1.45e-1)" "unprognostic (1.44e-1)" "prognostic unfavourable (3.89e-4)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (2.48e-3)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "unprognostic (6.46e-2)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (2.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" 26.6 25.2 18.4 28.4 21.9 32.0 26.1 37.2 25.8 24.4 23.6 23.7 20.6 18.4 34.7 22.6 23.4 26.5 22.0 22.0 19.7 12.3 19.0 25.8 22.7 25.1 16.6 18.9 39.3 22.7 49.4 25.2 33.7 18.9 21.3 22.0 25.5 28.3 23.0 39.7 25.3 27.6 28.3 15.8 25.2 23.4 34.3 19.5 57.3 25.3 21.3 31.2 33.7 24.0 8.5 7.7 15.3 7.5 9.1 12.6 6.0 23.1 26.3 35.3 26.5 16.5 14.6 33.2 16.0 19.6 29.3 28.1 47.8 17.0 40.3 25.4 20.4 18.4 64.8 21.8 30.4 21.8 34.2 51.6 41.9 25.9 10.7 39.5 22.7 15.1 13.6 33.3 28.4 23.8 45.1 27.2 16.9 20.2 37.0 11.8 46.0 25.5 43.7 34.3 25.3 11.4 34.2 39.2 37.4 26.0 22.3 16.6 21.2 24.7 20.6 24.5 29.7 24.8 23.0 25.3 29.8 50.3 16.5 26.4 26.1 15.3 5.6 7.5 10.1 7.0 12.2 7.8 7.8 12.6 7.3 8.5 7.6 9.3 6.2 9.1 7.5 7.7 8.5 6.0 18.4 21.9 37.2 25.8 19.7 12.3 16.6 18.9 18.9 19.5 SPACA5 "dJ54B20.3, LYC5, LYZL5, PNPK6288, SLLP2, UNQ6288" ENSG00000171489 "Sperm acrosome associated 5" Q96QH8 X 48004336-48009729 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 15.1" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;NB-4: 3.9;RPMI-8226: 1.1;T-47d: 1.1;U-266/70: 1.2;U-266/84: 2.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 1.9" "Low lineage specificity" "Detected in single" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" "HPA044747: , HPA047149: " 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.8 0.0 0.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.5 0.4 0.3 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.2 0.0 0.0 15.1 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.9 0.9 0.0 0.4 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.4 0.0 0.7 0.0 1.2 2.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 1.9 0.3 SPACA5B LYZL5B ENSG00000171478 "Sperm acrosome associated 5B" Q96QH8 X 48130657-48132613 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 18.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 19 "T-reg: 1.9" "Lineage enriched" "Detected in single" 19 "T-cells: 1.9" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" "HPA044747: , HPA047149: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 SPAM1 "HYAL5, PH-20, SPAG15" ENSG00000106304 "Sperm adhesion molecule 1" P38567 7 123925237-123971414 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 19.6" "Cell line enhanced" "Detected in some" "BEWO: 1.2;NTERA-2: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA017984 Enhanced "HPA017984: AB_1857413" "unprognostic (2.44e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPAST "ADPSP, FSP2, KIAA1083, SPG4" ENSG00000021574 Spastin Q9UBP0 2 32063547-32157637 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis" "Allosteric enzyme, Developmental protein, Isomerase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017311 Approved Approved Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA017311: AB_1857415" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (5.33e-2)" "unprognostic (3.90e-2)" "unprognostic (3.75e-2)" "unprognostic (4.00e-2)" "prognostic unfavourable (1.62e-4)" "unprognostic (3.26e-2)" "unprognostic (2.35e-2)" "unprognostic (7.39e-2)" "unprognostic (5.98e-2)" "unprognostic (3.52e-1)" "prognostic unfavourable (4.15e-4)" "unprognostic (5.71e-2)" "unprognostic (3.04e-1)" "unprognostic (1.53e-2)" "unprognostic (1.13e-1)" 12.7 9.6 18.4 14.8 16.4 13.4 9.8 21.1 21.9 14.7 12.7 15.1 12.5 11.5 12.3 8.7 11.1 10.4 10.2 6.2 20.2 18.5 9.4 14.6 9.7 18.9 20.6 10.0 15.1 10.9 11.8 12.3 11.5 17.5 10.3 12.0 6.8 9.3 13.7 15.4 11.5 17.6 11.6 27.0 15.5 9.7 14.4 14.6 21.5 13.4 6.2 13.8 11.3 10.1 5.0 7.1 9.5 9.0 6.6 7.6 4.3 10.6 7.7 12.6 12.4 8.0 9.4 11.4 5.9 8.7 6.2 5.6 10.4 9.3 18.6 5.5 8.2 7.6 12.4 6.0 7.7 12.5 7.5 20.5 4.2 12.7 7.3 14.2 14.4 5.2 7.9 7.9 7.6 13.7 16.6 6.3 6.8 4.5 22.8 12.0 13.1 4.5 12.1 17.8 12.1 8.4 6.6 18.0 19.3 10.0 8.5 9.8 5.5 9.8 11.8 6.9 10.6 6.1 6.9 9.5 17.7 15.1 7.5 12.3 8.2 3.4 6.3 6.7 3.6 9.0 5.2 5.0 5.8 5.6 7.1 3.9 5.9 6.0 9.5 6.6 6.3 3.2 7.6 4.3 18.4 16.4 21.1 15.8 20.2 18.5 20.6 10.0 17.5 14.6 SSH1 KIAA1298 ENSG00000084112 "Slingshot protein phosphatase 1" Q8WYL5 12 108778192-108857590 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019845 Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA019845: AB_1857497" "unprognostic (1.18e-3)" "unprognostic (3.00e-1)" "unprognostic (2.49e-1)" "unprognostic (2.70e-2)" "unprognostic (9.40e-2)" "unprognostic (7.45e-2)" "prognostic unfavourable (5.80e-5)" "unprognostic (3.28e-2)" "unprognostic (3.69e-2)" "unprognostic (1.72e-3)" "unprognostic (7.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.71e-2)" "unprognostic (1.41e-1)" "unprognostic (8.66e-2)" "unprognostic (9.55e-2)" "unprognostic (6.22e-2)" 7.3 7.8 8.5 7.4 8.1 10.6 9.3 20.3 8.8 7.4 8.5 6.8 13.1 4.4 9.8 7.9 7.6 8.2 8.3 10.1 8.0 6.9 5.8 7.4 10.1 8.7 7.7 5.2 7.9 8.0 9.7 6.8 7.8 8.4 6.5 6.5 15.0 5.9 8.0 21.4 7.1 6.5 10.4 8.1 8.6 7.1 5.2 6.6 2.0 7.0 7.9 6.6 10.0 13.3 1.8 2.0 5.7 4.0 2.1 2.9 1.2 5.1 6.8 4.5 3.5 8.5 7.2 4.0 6.6 14.1 6.0 5.4 3.4 2.5 2.4 4.7 15.5 5.1 2.7 11.1 4.9 4.9 2.6 5.7 3.1 2.1 4.5 2.9 15.1 9.9 3.8 5.5 12.2 5.5 1.3 2.0 15.8 2.9 3.3 4.2 3.1 5.4 2.4 5.3 3.2 2.4 9.2 3.3 4.5 5.8 1.5 12.7 2.1 2.6 4.3 10.9 4.6 6.5 3.7 3.9 3.5 3.0 5.7 2.4 34.2 4.2 2.4 4.8 2.9 4.0 2.7 1.6 1.5 2.5 1.6 1.8 1.4 1.6 5.7 2.1 3.2 2.0 1.7 1.2 8.5 8.1 20.3 8.8 8.0 6.9 7.7 5.2 8.4 6.6 SSH2 KIAA1725 ENSG00000141298 "Slingshot protein phosphatase 2" Q76I76 17 29625938-29930276 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 37.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017189, HPA057099" Uncertain "CAB017189: , HPA057099: " "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (3.00e-3)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-3)" "unprognostic (7.52e-2)" "unprognostic (1.48e-2)" "unprognostic (8.28e-2)" "unprognostic (7.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" 12.3 7.7 15.8 19.0 16.0 43.1 7.9 23.9 18.0 6.8 10.6 17.5 8.8 7.4 6.1 8.5 9.4 6.5 7.9 12.0 12.9 8.4 10.8 9.8 15.1 20.9 13.6 12.4 3.7 11.8 6.4 6.5 8.8 10.6 5.1 10.0 7.9 8.6 11.6 59.6 10.5 14.5 6.9 12.6 21.3 10.3 26.1 15.2 22.7 10.7 9.5 19.9 7.8 6.5 7.9 4.0 37.8 4.5 1.4 5.9 1.8 11.9 9.7 6.2 5.3 17.3 11.9 3.6 5.9 6.8 9.8 10.4 5.2 4.5 9.9 9.5 7.0 13.9 7.6 8.6 11.4 3.5 13.6 6.9 9.9 7.7 8.2 7.3 14.9 13.9 5.8 10.4 6.9 22.4 4.9 7.8 6.9 3.3 34.5 7.5 4.6 5.0 16.6 15.8 17.4 17.0 9.4 10.5 11.7 8.6 9.6 17.2 6.4 7.7 12.3 6.7 13.7 11.7 7.1 11.8 7.8 24.8 7.9 5.8 6.1 11.0 3.8 37.8 3.5 4.5 2.9 7.5 4.4 3.5 4.0 7.9 4.1 3.0 9.6 1.4 3.8 2.6 5.9 1.8 15.8 16.0 23.9 18.0 12.9 8.4 13.6 12.4 10.6 15.2 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303448-67312607 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 23.6;RT4: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 10.8;eosinophil: 10.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavourable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 8.6 5.5 5.6 6.8 9.7 8.1 13.5 17.8 9.4 14.6 15.9 15.4 19.5 12.4 10.1 10.6 27.0 15.2 20.5 7.7 6.0 6.1 10.3 7.5 9.0 3.5 13.6 5.4 17.1 12.0 11.3 7.4 20.0 8.5 19.8 9.2 11.9 19.1 30.5 5.2 18.2 13.6 13.1 9.3 6.9 13.9 4.2 9.7 0.8 12.8 14.0 13.2 33.3 18.6 0.3 1.6 10.8 2.3 1.5 2.2 1.0 6.1 6.7 0.1 0.2 4.7 4.9 7.3 4.0 5.4 2.1 2.0 7.2 16.3 0.3 12.5 3.7 23.6 2.2 17.0 1.1 1.3 2.5 1.5 10.8 2.9 3.3 0.3 6.0 4.3 15.8 3.1 3.2 2.4 0.0 0.6 2.5 20.8 0.2 3.0 1.5 5.4 7.6 0.2 1.1 6.9 35.7 1.4 2.2 9.4 14.0 4.4 19.6 5.2 3.8 1.7 3.7 4.7 1.1 0.6 0.3 0.2 4.8 2.7 1.6 10.8 1.4 10.5 2.2 2.3 1.7 0.3 2.1 1.8 1.6 0.2 0.8 0.9 4.5 1.5 1.1 1.1 1.8 1.0 5.6 9.7 17.8 9.4 6.0 6.1 13.6 5.4 8.5 9.7 SSU72 HSPC182 ENSG00000160075 "SSU72 homolog, RNA polymerase II CTD phosphatase" Q9NP77 1 1541673-1574869 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069290, HPA070604" Supported Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA069290: , HPA070604: " "unprognostic (3.33e-2)" "unprognostic (2.79e-2)" "unprognostic (6.37e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "unprognostic (9.84e-2)" "unprognostic (2.40e-3)" "unprognostic (2.43e-2)" "unprognostic (3.23e-1)" "unprognostic (3.23e-1)" "unprognostic (6.75e-2)" "unprognostic (1.36e-1)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "unprognostic (8.51e-2)" "unprognostic (3.77e-1)" "unprognostic (1.06e-1)" 44.1 32.5 48.0 33.6 51.5 29.3 73.9 42.3 51.5 37.2 40.1 25.4 39.3 41.3 32.6 51.8 45.7 46.2 35.3 44.4 40.7 42.5 38.0 50.9 37.5 49.0 39.4 39.0 38.0 61.8 33.9 39.9 35.8 36.9 33.9 35.9 34.1 54.2 35.8 107.1 36.9 40.8 35.4 35.0 41.7 38.5 28.0 28.4 37.0 50.9 45.3 36.3 30.8 42.2 35.5 30.1 62.0 28.8 20.7 46.5 28.1 40.6 26.0 18.8 29.0 32.5 31.3 19.3 35.3 27.6 30.9 32.2 24.4 47.2 41.4 19.4 27.8 31.8 30.3 29.1 30.2 34.4 35.9 25.9 22.9 38.6 36.7 32.8 22.7 27.9 24.6 33.1 31.6 28.9 44.8 32.0 24.4 36.2 37.5 52.7 32.9 39.6 29.9 30.4 57.8 33.8 12.5 34.8 23.9 23.9 61.5 104.3 32.0 28.6 21.9 29.8 18.9 33.5 30.3 39.1 46.9 51.6 31.2 52.3 14.4 37.1 28.3 53.6 25.9 28.8 31.9 35.5 34.4 30.7 30.1 33.1 42.2 34.1 62.0 20.7 25.4 19.0 46.5 28.1 48.0 51.5 42.3 51.5 40.7 42.5 39.4 39.0 36.9 28.4 ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "Suppression of tumorigenicity 14" Q9Y5Y6 11 130159562-130210376 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 94.1" "Cell line enhanced" "Detected in some" "CACO-2: 35.7;CAPAN-2: 72.1;HaCaT: 50.5;RPMI-8226: 47.3;SK-BR-3: 33.4;T-47d: 50.5;U-698: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 18.2" "Lineage enriched" "Detected in many" 5 "dendritic cells: 18.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047014 Approved Nucleoplasm,Vesicles 220000 "Nucleoplasm, Vesicles" "HPA047014: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favourable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" 10.1 1.8 0.7 21.9 1.8 0.5 5.5 0.8 1.4 8.9 48.6 0.5 23.8 33.8 2.8 16.9 38.9 9.7 32.4 1.1 0.5 0.5 30.5 3.2 9.5 7.5 1.8 0.6 3.6 34.3 8.4 9.5 12.7 1.5 12.1 15.4 0.7 25.1 15.8 0.7 17.8 94.1 1.2 1.8 4.0 16.7 2.1 1.5 5.2 24.0 20.1 28.4 8.3 14.9 3.8 18.2 2.3 2.7 0.0 0.1 0.8 26.2 0.0 0.0 0.1 0.0 0.0 14.3 0.0 0.0 0.0 0.0 35.7 72.1 26.0 2.7 0.0 50.5 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 20.3 0.0 0.1 0.2 0.1 0.0 0.0 47.3 4.7 21.5 2.9 0.0 0.2 33.4 0.0 50.5 5.1 0.0 0.0 0.4 0.1 0.1 0.0 0.0 34.4 0.0 8.0 0.0 0.0 2.7 2.3 0.0 1.5 0.1 3.8 0.0 0.0 4.5 2.3 0.0 0.0 0.3 0.0 0.2 18.2 0.0 0.8 0.7 1.8 0.8 1.4 0.5 0.5 1.8 0.6 1.5 1.5 STS "ARSC, ARSC1" ENSG00000101846 "Steroid sulfatase" P08842 X 7219456-7354810 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Pregnancy, Steroid metabolism" Hydrolase "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "placenta: 258.8" "Cell line enhanced" "Detected in many" "ASC diff: 19.9;RPMI-8226: 25.4;U-266/70: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 4.7" "Low lineage specificity" "Detected in many" HPA002904 Enhanced "HPA002904: AB_1080116" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (2.75e-1)" "unprognostic (6.72e-2)" "unprognostic (1.94e-2)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (8.23e-2)" "unprognostic (4.67e-2)" "prognostic unfavourable (3.47e-4)" "unprognostic (4.05e-2)" "unprognostic (2.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" 10.3 2.2 3.0 2.2 3.9 0.0 4.1 2.3 9.0 3.4 3.5 2.3 2.2 0.8 2.4 2.2 2.2 2.6 4.1 3.6 3.9 4.0 2.5 4.7 5.0 2.2 3.8 2.4 2.4 2.2 1.6 2.2 258.8 2.4 2.9 3.0 2.3 2.2 3.3 4.0 2.3 2.4 3.8 2.4 2.2 6.7 2.2 2.3 2.2 2.4 2.2 2.2 4.9 2.7 0.9 1.9 1.9 4.7 1.0 0.7 1.0 4.0 1.2 2.7 0.9 19.9 10.3 14.7 8.3 3.0 2.2 2.1 7.2 3.8 7.6 1.6 6.0 1.0 1.6 1.3 2.2 0.6 3.2 0.4 4.6 2.0 1.1 1.1 4.3 3.4 0.2 1.4 0.8 3.4 0.4 7.9 5.9 0.9 0.6 1.0 1.0 1.8 1.0 1.6 25.4 5.6 5.9 2.0 1.7 1.6 3.0 0.9 1.2 0.4 5.9 8.9 0.5 11.4 1.3 42.2 0.0 17.7 2.1 0.9 2.3 0.0 3.2 0.6 0.5 4.7 0.2 0.6 0.2 0.3 1.9 0.9 0.1 0.5 1.9 1.0 2.5 0.3 0.7 1.0 3.0 3.9 2.3 9.0 3.9 4.0 3.8 2.4 2.4 2.3 SUPV3L1 SUV3 ENSG00000156502 "Suv3 like RNA helicase" Q8IYB8 10 69180232-69209099 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038380, HPA038405" Supported Supported Mitochondria Mitochondria "HPA038380: AB_2675983, HPA038405: AB_10675797" "unprognostic (4.70e-2)" "unprognostic (1.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-2)" "unprognostic (3.74e-2)" "unprognostic (3.32e-2)" "unprognostic (1.44e-2)" "unprognostic (1.78e-1)" "unprognostic (1.57e-1)" "unprognostic (9.47e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (5.48e-3)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (5.27e-2)" "unprognostic (1.33e-1)" 12.8 17.0 11.1 12.6 17.3 26.1 17.7 21.9 19.9 10.8 14.4 12.6 7.8 11.2 13.5 12.4 13.2 11.9 12.6 19.2 12.0 11.3 16.4 22.2 9.6 15.2 9.9 13.1 15.8 18.2 15.4 14.7 10.9 16.1 11.4 16.7 12.4 11.8 13.9 31.1 15.6 12.5 13.9 9.9 15.5 13.0 26.6 9.9 12.7 14.1 13.4 14.8 12.4 11.6 10.1 7.3 5.6 7.7 7.4 13.7 6.2 11.3 7.9 7.1 21.8 8.0 6.8 9.4 7.0 10.9 14.3 13.5 20.3 9.6 20.4 5.8 7.1 13.0 17.1 11.0 13.8 8.5 13.4 8.9 6.2 10.7 20.3 21.1 6.8 8.6 13.9 13.1 30.2 8.2 23.2 10.6 7.8 7.3 12.8 13.1 8.5 43.4 11.8 10.1 8.9 6.5 5.5 10.2 7.7 9.7 20.4 18.5 6.3 9.3 5.1 5.7 10.3 8.6 13.6 8.4 9.8 19.0 9.4 22.4 3.6 5.6 5.2 4.3 12.3 7.7 13.7 10.1 8.9 10.5 7.3 8.3 9.9 10.6 0.9 7.4 5.2 4.0 8.7 6.2 11.1 17.3 21.9 19.9 12.0 11.3 9.9 13.1 16.1 9.9 SYNJ1 "INPP5G, PARK20" ENSG00000159082 "Synaptojanin 1" O43426 21 32628759-32728048 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, RNA-binding" "Disease mutation, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011916 Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Nucleoplasm, Cytosol" Centrosome "HPA011916: AB_1857692" "unprognostic (6.84e-2)" "unprognostic (8.64e-2)" "unprognostic (5.76e-2)" "unprognostic (6.44e-2)" "unprognostic (1.27e-1)" "prognostic favourable (4.43e-4)" "unprognostic (1.45e-1)" "unprognostic (3.73e-3)" "unprognostic (1.63e-1)" "unprognostic (6.22e-3)" "unprognostic (1.84e-2)" "prognostic unfavourable (2.58e-4)" "unprognostic (1.28e-1)" "unprognostic (6.36e-2)" "unprognostic (5.97e-2)" "unprognostic (1.79e-1)" "unprognostic (2.92e-1)" 5.5 6.8 13.6 5.0 25.9 20.6 4.2 19.5 39.0 4.8 4.8 6.5 0.8 3.9 4.6 5.3 3.9 4.0 5.2 5.2 18.3 18.2 7.4 5.5 6.5 5.7 16.6 18.4 4.6 4.5 10.6 10.9 9.3 33.5 3.6 5.5 7.0 3.8 4.0 4.4 5.0 4.6 5.0 7.3 6.0 4.2 9.0 5.7 3.2 6.8 1.5 4.8 4.7 3.3 0.4 3.1 11.5 6.0 0.5 3.0 1.1 5.5 2.8 5.1 5.6 8.9 7.2 10.3 11.5 6.6 7.0 5.9 6.3 2.6 2.0 3.9 6.9 5.2 9.1 6.7 8.4 6.5 8.7 13.8 9.0 3.5 4.8 5.7 12.3 4.0 5.0 12.2 6.2 10.9 10.3 11.9 9.0 5.6 5.3 4.7 3.6 6.3 5.8 11.1 7.2 7.4 4.0 5.8 4.5 14.1 9.0 5.5 7.8 7.4 12.1 10.9 5.4 8.7 6.3 6.2 7.2 4.3 8.2 10.8 8.6 3.7 3.4 7.9 1.6 6.0 2.7 0.2 2.4 2.6 3.1 0.4 2.9 2.8 11.5 0.5 5.3 1.6 3.0 1.1 13.6 25.9 19.5 28.7 18.3 18.2 16.6 18.4 33.5 5.7 SYNJ2 INPP5H ENSG00000078269 "Synaptojanin 2" O15056 6 157981887-158099176 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 62.0" "Cell line enhanced" "Detected in many" "TIME: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031575 Approved Approved Microtubules,Cytosol Microtubules Cytosol "HPA031575: AB_10604101" "prognostic unfavourable (2.63e-4)" "unprognostic (1.94e-2)" "unprognostic (7.61e-2)" "unprognostic (1.25e-2)" "unprognostic (1.48e-2)" "unprognostic (7.68e-2)" "unprognostic (1.24e-1)" "unprognostic (7.06e-2)" "unprognostic (2.91e-1)" "unprognostic (7.29e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "prognostic unfavourable (4.02e-6)" "unprognostic (1.66e-2)" "unprognostic (3.75e-2)" "unprognostic (1.75e-1)" "unprognostic (9.45e-2)" 2.8 3.9 12.2 4.9 25.1 15.3 6.7 3.0 18.7 3.9 8.7 50.5 3.7 5.8 5.2 9.4 6.0 4.6 8.0 8.5 17.8 10.9 3.2 4.0 2.8 4.4 46.8 8.8 2.9 6.6 1.1 2.9 2.6 33.0 5.3 8.9 1.4 13.5 5.1 4.3 3.1 5.6 6.6 62.0 3.3 7.0 6.5 24.4 3.0 4.4 1.4 5.3 5.9 3.0 3.2 1.1 9.3 1.3 2.4 3.8 0.8 5.9 20.9 1.7 2.7 1.3 4.3 9.3 11.0 22.4 13.2 15.6 10.7 5.1 0.2 7.5 21.2 5.7 3.7 6.9 15.4 8.3 3.4 11.6 10.9 11.3 2.5 4.0 12.6 2.2 3.7 20.1 4.7 22.9 8.8 2.6 6.0 2.8 5.0 4.5 2.0 11.7 2.2 7.2 5.3 4.4 6.9 13.3 0.7 8.5 5.4 2.1 4.2 2.5 40.5 10.0 10.3 23.1 13.3 1.1 2.8 0.3 18.8 6.4 6.9 4.5 1.3 1.1 1.9 0.6 3.8 1.9 2.6 1.7 1.1 3.2 2.2 1.7 9.3 2.4 0.8 1.1 2.1 0.8 12.2 25.1 3.0 18.7 17.8 10.9 46.8 8.8 33.0 24.4 TDG ENSG00000139372 "Thymine DNA glycosylase" Q13569 12 103965804-103988874 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052263 Supported Supported Nucleoplasm Nucleoplasm "HPA052263: " "unprognostic (3.15e-1)" "unprognostic (1.36e-1)" "unprognostic (9.89e-3)" "unprognostic (6.93e-2)" "unprognostic (3.66e-2)" "unprognostic (1.13e-1)" "prognostic unfavourable (6.27e-5)" "unprognostic (1.56e-2)" "prognostic unfavourable (6.90e-5)" "unprognostic (5.37e-2)" "unprognostic (1.82e-1)" "unprognostic (8.48e-2)" "prognostic unfavourable (1.90e-10)" "unprognostic (3.68e-1)" "unprognostic (2.90e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" 12.3 16.6 7.0 17.9 11.1 15.9 12.8 10.7 13.4 17.7 14.7 10.0 11.3 11.0 15.8 17.8 23.8 12.4 12.8 12.0 7.7 6.9 13.4 17.4 13.7 19.7 8.7 7.9 14.4 13.2 11.0 21.0 27.9 10.8 13.0 16.8 10.9 13.2 11.3 11.1 16.3 18.7 17.8 8.8 19.8 13.1 5.8 8.1 33.4 12.4 15.3 19.6 13.3 14.7 18.9 41.4 18.8 24.3 14.2 13.6 7.2 13.2 6.7 21.2 12.3 5.3 4.7 21.4 10.0 4.1 14.0 7.9 11.4 6.0 31.2 6.1 8.3 8.8 25.3 11.8 11.1 12.7 20.5 24.5 10.1 5.1 4.9 30.4 18.6 5.5 15.7 10.4 8.4 13.7 27.3 5.2 6.8 13.8 33.9 17.1 25.7 10.8 35.0 10.9 11.1 15.4 19.6 28.0 19.4 12.2 14.3 8.9 22.9 16.4 8.3 4.4 7.2 4.6 11.8 11.4 15.1 26.8 4.8 16.4 8.4 18.5 24.3 18.8 13.6 16.3 10.3 17.7 13.0 11.2 14.9 18.9 13.5 12.1 16.0 14.2 15.9 41.4 12.6 7.2 7.0 11.1 10.7 13.4 7.7 6.9 8.7 7.9 10.8 8.1 TDRD12 "ECAT8, FLJ13072" ENSG00000173809 "Tudor domain containing 12" Q587J7 19 32719753-32829580 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 36.1" "Group enriched" "Detected in some" 30 "HDLM-2: 12.5;NTERA-2: 41.6" "Cancer enriched" "Detected in many" 9 "testis cancer: 10.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive CD8 T-cell: 1.8" "Lineage enriched" "Detected in single" 4 "T-cells: 1.8" "Low region specificity" "Detected in many" "unprognostic (5.43e-2)" "unprognostic (3.97e-1)" "unprognostic (1.14e-1)" "unprognostic (1.87e-7)" "unprognostic (5.44e-2)" "unprognostic (1.78e-1)" "unprognostic (6.79e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.40e-1)" "unprognostic (9.69e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-4)" "unprognostic (2.09e-1)" "unprognostic (4.75e-2)" "unprognostic (3.08e-2)" "unprognostic (2.69e-2)" 0.2 0.7 0.2 0.1 0.4 0.0 0.4 0.2 0.5 0.9 0.3 0.2 0.6 0.0 1.1 8.5 0.2 1.1 0.3 0.3 0.1 0.2 0.9 0.1 0.2 0.8 0.3 0.1 1.8 0.1 0.0 0.2 0.2 0.6 0.2 0.0 0.3 0.2 0.6 0.1 1.7 1.2 0.1 0.1 0.9 0.2 36.1 0.1 0.6 0.9 0.1 0.6 0.5 0.3 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.1 0.6 0.0 0.0 0.9 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 12.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 41.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.4 0.2 0.5 0.1 0.2 0.3 0.1 0.6 0.1 TDRD9 "C14orf75, DKFZp434N0820, FLJ36164, NET54" ENSG00000156414 "Tudor domain containing 9" Q8NDG6 14 103928462-104052667 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "parathyroid gland: 19.9;testis: 48.0" "Cell line enhanced" "Detected in some" "HDLM-2: 10.8;HeLa: 9.5;HMC-1: 44.1;RPTEC TERT1: 12.0;SK-MEL-30: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 5 "classical monocyte: 4.6" "Lineage enriched" "Detected in single" 5 "monocytes: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (3.71e-1)" "unprognostic (3.02e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (1.91e-1)" "unprognostic (1.55e-1)" "unprognostic (2.74e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "unprognostic (1.61e-1)" "unprognostic (2.13e-4)" "unprognostic (1.60e-2)" "unprognostic (4.57e-3)" "unprognostic (8.97e-2)" "unprognostic (3.34e-1)" "prognostic unfavourable (5.52e-4)" "unprognostic (2.41e-2)" 0.4 0.4 0.7 0.4 1.5 1.2 0.5 1.5 1.5 0.3 0.3 0.8 0.6 0.1 0.3 0.3 0.2 0.7 2.1 0.6 0.8 0.7 1.8 0.5 1.0 0.3 0.8 1.3 0.3 0.7 19.9 0.9 0.4 3.4 0.3 0.1 1.8 0.9 1.0 0.1 0.1 0.3 0.4 1.6 2.8 0.6 48.0 0.5 0.2 4.2 0.0 0.8 0.4 0.2 0.0 0.8 0.0 4.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 9.5 0.0 0.0 0.0 44.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 4.0 0.0 0.0 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 1.5 1.5 1.5 0.8 0.7 0.8 1.3 3.4 0.5 THEM4 CTMP ENSG00000159445 "Thioesterase superfamily member 4" Q5T1C6 1 151873584-151909808 "Enzymes, Predicted intracellular proteins" "Apoptosis, Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028161 Approved "HPA028161: AB_10603454" "unprognostic (2.88e-2)" "unprognostic (1.93e-1)" "unprognostic (1.50e-1)" "unprognostic (1.04e-2)" "unprognostic (1.29e-1)" "unprognostic (7.89e-2)" "prognostic unfavourable (1.38e-4)" "unprognostic (3.15e-3)" "unprognostic (2.23e-2)" "unprognostic (1.07e-1)" "prognostic favourable (2.51e-4)" "unprognostic (1.17e-1)" "unprognostic (4.19e-2)" "unprognostic (3.02e-2)" "unprognostic (9.25e-2)" "unprognostic (1.91e-1)" "unprognostic (5.93e-3)" 8.3 15.3 8.4 9.8 11.7 4.9 12.2 19.8 13.2 6.6 8.0 11.3 22.4 8.5 10.3 18.0 6.1 8.5 7.2 9.8 8.7 11.9 19.9 13.4 8.9 15.7 10.8 6.4 9.2 15.9 10.9 21.0 6.3 11.1 8.0 11.6 14.9 9.2 23.1 18.3 6.7 8.1 7.9 10.0 9.2 9.6 10.2 11.8 3.1 11.3 6.4 13.6 11.3 8.3 3.0 5.0 1.8 1.6 6.2 18.6 2.8 3.7 4.3 1.0 3.4 3.7 2.9 3.3 3.1 3.7 4.2 3.5 4.7 3.2 10.0 4.9 4.5 3.9 2.9 9.8 4.2 10.4 2.0 13.6 5.9 5.4 3.5 15.6 4.4 5.8 4.4 4.5 4.5 7.1 17.0 7.7 6.1 6.3 0.0 4.2 17.8 7.5 0.0 0.7 2.6 5.0 3.7 4.6 8.2 2.1 4.0 30.0 10.2 6.5 6.2 0.4 3.7 2.8 1.3 12.5 16.1 6.4 6.4 8.6 20.0 1.5 0.6 1.8 6.1 1.6 9.1 3.0 12.7 6.0 2.0 1.5 12.3 8.7 0.4 6.2 0.5 5.0 18.6 2.8 8.4 11.7 19.8 13.2 8.7 11.9 10.8 6.4 11.1 11.8 THEM5 FLJ37964 ENSG00000196407 "Thioesterase superfamily member 5" Q8N1Q8 1 151847263-151853697 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skin 1: 59.8;tongue: 24.7" "Cell line enriched" "Detected in some" 6 "HDLM-2: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "MAIT T-cell: 4.2" "Lineage enriched" "Detected in single" 7 "T-cells: 4.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "basal ganglia: 20.0" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (3.41e-2)" "unprognostic (2.58e-3)" "unprognostic (9.55e-3)" "unprognostic (1.27e-1)" "unprognostic (1.93e-1)" "unprognostic (1.83e-1)" "unprognostic (7.86e-3)" "unprognostic (3.07e-3)" "unprognostic (9.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.34e-2)" "unprognostic (1.62e-2)" 0.1 0.6 0.3 0.5 0.2 0.0 1.8 0.2 1.6 3.6 0.1 0.2 0.1 0.3 0.8 0.1 4.4 0.1 1.0 1.1 0.3 0.2 0.3 0.2 0.3 1.9 0.2 0.8 0.1 0.3 0.0 0.2 5.8 0.1 0.1 0.0 0.1 1.5 0.1 0.2 59.8 0.1 0.1 0.3 0.1 0.5 0.3 0.1 0.4 0.1 24.7 1.7 0.6 1.1 0.0 0.5 0.5 0.2 0.0 4.2 5.6 4.3 0.0 0.0 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 1.6 0.0 0.0 0.0 38.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.2 0.1 0.0 4.6 0.3 0.0 0.2 0.5 0.0 0.0 0.3 0.1 5.9 1.4 0.8 1.0 1.4 0.0 0.0 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 1.8 0.2 4.2 0.0 1.6 1.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.5 1.9 5.6 0.3 0.2 0.2 1.3 0.3 0.2 0.2 0.8 0.1 0.1 THOP1 ENSG00000172009 "Thimet oligopeptidase 1" P52888 19 2785460-2815807 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025497, HPA035262" Uncertain Supported Cytosol 1400000 Cytosol "CAB025497: , HPA035262: " "unprognostic (1.52e-2)" "unprognostic (1.73e-3)" "unprognostic (7.94e-2)" "prognostic favourable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" "unprognostic (1.19e-1)" "unprognostic (4.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-3)" "unprognostic (3.00e-2)" "unprognostic (1.39e-1)" "prognostic favourable (5.90e-4)" "unprognostic (1.27e-1)" "unprognostic (2.64e-1)" "unprognostic (5.37e-2)" 8.2 9.4 19.1 12.3 19.8 18.4 6.2 21.7 26.1 5.2 11.8 14.1 5.8 24.6 7.5 8.4 11.0 8.4 6.7 11.6 18.5 15.4 7.1 30.4 6.2 11.9 14.1 15.2 11.1 7.8 7.0 12.7 22.3 13.1 18.1 8.2 11.9 13.7 6.8 29.1 11.9 20.0 7.1 10.7 9.8 7.8 27.3 10.9 17.0 7.5 11.5 11.3 5.8 6.8 7.5 9.8 8.0 7.5 3.9 9.5 3.2 29.2 21.8 8.5 18.2 4.4 4.3 30.4 18.3 6.8 18.2 14.8 25.6 9.4 26.4 9.0 7.1 23.8 12.6 15.0 7.7 0.1 26.5 9.3 24.0 30.2 4.7 18.0 14.6 4.8 5.4 15.1 6.8 10.3 21.7 12.9 7.7 22.7 20.0 33.8 25.1 30.1 16.7 11.3 25.0 7.6 17.0 23.1 18.5 16.0 14.4 8.9 14.0 17.5 11.7 14.0 12.1 29.8 30.9 22.7 19.0 17.8 15.6 30.3 16.6 8.0 3.5 1.6 5.5 3.9 4.5 5.6 4.0 7.4 4.9 7.5 5.1 4.3 1.7 3.9 7.5 9.8 9.5 3.2 19.1 19.8 21.7 26.1 18.5 15.4 14.1 15.2 13.1 10.9 THTPA THTPASE ENSG00000259431 "Thiamine triphosphatase" Q9BU02 14 23555988-23560271 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028876 Approved Uncertain Nucleoplasm,Nucleoli Nucleoplasm Nucleoli "HPA028876: AB_10600731" "unprognostic (3.50e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (7.11e-2)" "unprognostic (2.25e-1)" "unprognostic (2.12e-1)" "unprognostic (4.13e-1)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.50e-1)" "prognostic favourable (1.70e-9)" "unprognostic (3.47e-2)" "unprognostic (2.32e-1)" "unprognostic (3.62e-2)" "unprognostic (5.40e-2)" 14.9 19.5 27.7 12.2 23.3 7.6 12.9 16.4 24.3 12.3 14.0 20.7 15.9 15.7 13.3 18.4 10.1 17.7 16.8 16.3 23.3 17.4 16.3 12.1 10.7 10.7 21.9 13.3 15.4 12.7 25.0 12.4 7.6 16.1 18.8 12.3 17.1 18.0 23.5 21.9 7.4 11.7 13.7 19.5 11.3 11.6 18.8 14.3 14.1 15.9 12.3 11.2 9.9 7.9 14.3 17.0 11.1 14.4 6.9 11.6 8.7 2.7 17.2 8.5 9.1 19.4 11.0 4.7 8.0 7.1 8.0 7.9 3.5 11.4 5.2 7.1 9.6 8.5 8.9 10.0 5.9 11.0 9.6 7.1 12.1 9.4 9.8 6.5 6.4 14.8 7.4 12.1 9.0 9.5 5.3 11.5 11.5 8.2 10.2 2.7 3.0 14.6 7.0 5.7 9.5 14.0 5.5 16.3 7.8 7.9 16.3 4.7 10.9 3.2 7.5 5.2 5.6 10.8 4.7 13.6 8.2 2.9 5.5 2.9 8.0 11.1 14.4 7.3 9.6 10.6 9.5 9.6 6.9 7.5 13.2 14.3 11.6 9.9 1.5 6.9 13.4 17.0 5.4 8.7 27.7 23.3 16.4 24.3 23.3 17.4 21.9 13.3 16.1 14.3 TIGAR C12orf5 ENSG00000078237 "TP53 induced glycolysis regulatory phosphatase" Q9NQ88 12 4307763-4354593 "Enzymes, Predicted intracellular proteins" "Apoptosis, Autophagy" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034010, HPA040354, HPA044111" Approved Supported Cytosol Cytosol "CAB034010: AB_1128227, HPA040354: , HPA044111: " "unprognostic (1.76e-1)" "unprognostic (6.33e-2)" "unprognostic (4.08e-1)" "unprognostic (2.60e-1)" "unprognostic (1.32e-1)" "unprognostic (2.35e-1)" "prognostic unfavourable (3.18e-4)" "unprognostic (5.41e-2)" "unprognostic (2.11e-1)" "unprognostic (9.37e-2)" "unprognostic (1.85e-1)" "unprognostic (5.21e-2)" "unprognostic (2.03e-2)" "unprognostic (2.02e-3)" "unprognostic (2.44e-1)" "unprognostic (3.31e-1)" "unprognostic (1.05e-1)" 14.3 14.3 8.3 12.3 10.8 10.5 7.1 3.7 17.8 6.3 10.4 10.1 6.4 6.7 7.5 7.3 10.3 5.7 8.5 9.8 9.5 7.9 7.7 11.0 10.4 12.3 13.5 7.9 6.0 5.2 9.0 14.4 14.6 12.2 7.5 13.5 8.4 8.2 9.5 13.6 6.2 8.7 12.5 12.3 14.9 8.5 8.4 8.3 8.9 6.0 6.6 12.6 13.9 8.9 3.7 14.0 4.7 15.5 3.2 5.7 3.6 5.7 9.2 7.5 8.6 7.0 6.9 39.3 9.9 8.4 7.6 10.3 11.1 5.9 6.3 1.4 6.8 7.2 7.9 16.9 9.5 8.3 5.8 0.2 6.1 9.1 15.0 3.5 1.3 12.3 20.4 8.8 16.0 15.3 0.7 4.8 15.2 8.4 3.1 1.8 16.0 2.8 4.5 12.1 2.3 7.4 11.6 0.3 4.5 9.3 4.7 12.2 1.5 3.1 13.2 10.2 13.2 8.0 5.5 4.1 4.0 10.9 7.2 2.4 8.1 0.5 8.2 0.7 3.6 14.4 3.4 3.7 2.8 3.9 14.0 2.9 1.9 3.2 4.7 3.2 15.5 5.5 5.7 3.6 8.3 10.8 3.7 17.8 9.5 7.9 13.5 7.9 12.2 8.3 TMEM2 ENSG00000135048 "Transmembrane protein 2" Q9UHN6 9 71683366-71816690 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 67.6" "Cell line enhanced" "Detected in many" "AF22: 37.7;BEWO: 35.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044889 Approved Supported "Vesicles,Plasma membrane" 130000 "Plasma membrane" Vesicles "HPA044889: AB_10962641" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (6.15e-3)" "unprognostic (1.21e-2)" "unprognostic (2.93e-2)" "unprognostic (3.53e-1)" "unprognostic (3.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" "prognostic unfavourable (1.31e-4)" "unprognostic (1.13e-2)" "unprognostic (2.33e-1)" "unprognostic (7.59e-2)" "unprognostic (1.16e-1)" 23.3 3.9 6.0 10.5 4.4 12.4 13.6 8.9 6.0 3.0 18.6 1.9 10.1 12.2 4.5 5.2 4.4 4.9 19.2 9.5 8.6 3.6 9.3 24.9 35.7 14.0 4.0 4.1 3.1 9.2 24.0 9.5 67.6 4.3 5.5 13.1 7.9 9.5 10.2 5.5 6.4 20.0 5.5 5.1 15.6 14.5 3.7 2.4 6.4 8.0 4.6 8.8 11.4 6.8 6.3 0.9 5.5 2.1 0.5 4.1 1.4 5.9 28.8 37.7 1.7 3.9 7.1 35.0 20.3 13.0 14.1 10.4 8.1 8.2 0.1 6.1 5.2 9.0 12.2 2.8 19.2 0.7 3.7 10.3 6.1 21.4 6.1 0.0 2.8 7.3 3.1 10.9 2.4 18.5 1.4 3.0 7.6 5.0 1.2 0.1 7.8 2.8 0.9 11.2 0.8 8.9 19.4 1.9 0.2 5.3 3.7 5.4 2.6 0.4 8.1 9.6 10.8 5.3 10.1 0.6 8.7 0.3 1.8 0.9 12.1 0.2 2.1 5.5 2.7 1.9 0.8 0.7 2.9 2.6 0.9 6.3 4.1 2.0 4.5 0.5 1.8 0.2 3.9 1.4 6.0 4.4 8.9 6.0 8.6 3.6 4.0 4.1 4.3 2.4 TMEM86B MGC30208 ENSG00000180089 "Transmembrane protein 86B" Q8N661 19 55226639-55229264 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 15.1" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "liver cancer: 10.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057689 Uncertain Uncertain Midbody,Centrosome Centrosome Midbody "HPA057689: " "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.76e-5)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (6.55e-2)" "prognostic favourable (3.13e-4)" "unprognostic (1.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.10e-1)" "prognostic favourable (9.97e-6)" "unprognostic (1.96e-2)" "unprognostic (6.63e-8)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (3.70e-1)" "unprognostic (3.19e-3)" 2.5 2.4 2.8 3.1 4.0 7.8 1.4 4.7 4.2 1.4 7.5 1.4 1.4 5.6 1.5 1.4 1.4 1.8 7.7 2.9 2.2 1.6 2.0 15.1 2.7 5.2 1.4 1.4 1.4 1.4 1.7 2.8 5.2 1.7 1.5 0.4 1.4 1.4 1.4 2.2 3.0 7.7 1.4 1.4 4.3 3.6 2.8 1.4 1.4 2.3 1.4 3.0 1.4 1.4 0.7 1.0 0.6 0.7 0.0 1.6 0.4 4.1 3.9 2.4 3.9 0.4 0.6 3.6 1.4 0.7 1.3 1.8 6.3 2.2 4.7 1.2 1.1 1.7 0.9 1.0 0.6 0.9 11.1 8.8 2.5 5.9 1.2 3.9 3.7 0.8 1.7 2.1 1.3 0.5 6.0 3.5 0.8 2.4 6.4 10.0 0.9 2.4 5.9 2.8 12.5 1.1 5.1 2.1 3.9 1.8 0.8 4.9 2.2 8.3 2.8 5.7 3.2 2.5 3.8 2.9 3.4 10.2 4.7 11.1 2.1 0.0 0.7 0.6 1.6 0.1 0.6 0.0 0.5 0.1 0.1 0.7 0.6 1.4 0.1 0.0 0.1 1.0 0.0 0.4 2.8 4.0 4.7 4.2 2.2 1.6 1.4 1.4 1.7 1.4 TMEM8A "M83, PGAP6, TMEM6, TMEM8" ENSG00000129925 "Transmembrane protein 8A" Q9HCN3 16 370773-387113 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 24.3" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051281, HPA064673" Approved Supported "Nucleoplasm,Cytokinetic bridge" Nucleoplasm "Cytokinetic bridge" "HPA051281: , HPA064673: " "unprognostic (5.84e-2)" "unprognostic (6.13e-2)" "unprognostic (3.85e-2)" "unprognostic (3.21e-2)" "unprognostic (5.77e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-3)" "unprognostic (1.56e-2)" "unprognostic (8.89e-2)" "unprognostic (7.73e-2)" "unprognostic (3.43e-1)" "unprognostic (1.38e-2)" "prognostic favourable (1.29e-5)" "unprognostic (4.20e-3)" "unprognostic (3.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.48e-1)" 8.4 9.3 6.9 9.5 7.8 15.2 13.5 7.7 7.9 6.8 16.6 7.3 24.1 17.7 7.3 29.6 11.8 6.5 15.2 10.0 5.6 4.3 28.7 33.5 13.0 10.7 7.1 3.2 8.3 44.2 11.5 10.7 45.5 6.7 11.4 6.0 8.8 22.5 8.8 12.8 3.7 25.0 5.0 4.7 13.2 17.5 26.3 6.0 12.6 12.3 5.2 14.6 9.3 8.8 2.0 2.9 24.3 5.5 0.9 7.6 3.3 4.4 11.7 6.7 12.3 9.2 8.3 13.4 12.7 13.3 6.5 9.3 45.8 20.8 4.7 17.3 12.2 6.3 3.0 14.0 1.8 13.4 11.2 7.8 7.9 26.1 21.3 5.9 14.8 9.6 4.2 10.0 2.9 15.0 12.5 7.3 8.1 27.4 8.2 11.5 10.6 4.6 17.9 7.7 10.8 10.5 11.4 8.0 9.2 7.1 7.2 37.4 12.9 11.8 21.8 18.5 20.0 12.8 6.7 14.7 7.3 9.3 9.4 6.3 11.7 4.6 5.0 6.3 7.4 5.5 5.9 1.8 5.8 5.8 2.5 2.0 7.6 5.5 24.3 0.9 3.8 2.9 4.3 3.3 6.9 7.8 7.7 7.9 5.6 4.3 7.1 3.2 6.7 6.0 TMPRSS15 "ENTK, MGC133046, PRSS7" ENSG00000154646 "Transmembrane serine protease 15" P98073 21 18269116-18485879 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 67 "intestine: 154.6" "Group enriched" "Detected in some" 20 "U-138 MG: 19.8;U-87 MG: 55.3" "Group enriched" "Detected in some" 12 "liver cancer: 0.7;pancreatic cancer: 1.5;stomach cancer: 1.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 2.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "olfactory region: 9.3" "HPA015611, HPA034857, HPA072934" Enhanced Approved "Nucleoli,Plasma membrane" "Plasma membrane" Nucleoli "HPA015611: AB_1855791, HPA034857: , HPA072934: " "unprognostic (9.26e-2)" "unprognostic (4.14e-1)" "unprognostic (3.52e-1)" "unprognostic (8.33e-2)" "unprognostic (1.19e-1)" "unprognostic (7.20e-2)" "unprognostic (4.70e-2)" "unprognostic (6.35e-2)" "unprognostic (5.92e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 80.5 0.0 0.0 154.6 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 42.4 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.5 0.1 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.1 0.0 0.3 0.0 0.0 55.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 TNFAIP3 "A20, OTUD7C" ENSG00000118503 "TNF alpha induced protein 3" P21580 6 137867188-137883312 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Inflammatory response, Ubl conjugation pathway" "DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 112.4" "Cell line enhanced" "Detected in many" "Karpas-707: 48.4;REH: 42.0;U-266/84: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002116, HPA067479" Approved Supported Vesicles Vesicles "HPA002116: AB_1858162, HPA067479: " "unprognostic (5.50e-3)" "unprognostic (9.98e-3)" "unprognostic (3.06e-2)" "unprognostic (1.01e-2)" "unprognostic (4.01e-2)" "unprognostic (9.47e-2)" "unprognostic (5.01e-3)" "unprognostic (4.40e-2)" "unprognostic (2.92e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "prognostic unfavourable (6.05e-4)" "unprognostic (6.06e-2)" "unprognostic (3.55e-3)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" 27.4 6.0 1.5 58.6 1.8 112.4 17.2 0.4 1.5 7.7 15.7 3.2 2.6 5.1 9.7 7.3 12.7 12.1 17.0 11.7 2.1 1.3 6.8 8.1 45.1 38.8 2.1 2.6 37.5 7.2 2.1 3.7 14.5 4.6 13.8 6.3 7.2 8.2 3.5 10.7 20.5 17.2 8.2 3.8 25.9 8.0 9.3 2.1 38.6 5.7 9.2 31.4 23.3 9.5 7.1 18.6 10.0 9.7 7.5 20.5 9.0 8.9 1.5 0.5 0.8 3.0 5.1 2.1 5.1 20.0 1.4 1.8 9.9 3.0 2.0 13.2 5.9 6.8 0.3 14.8 2.6 14.6 0.5 2.0 5.2 5.8 3.3 2.7 3.7 4.7 2.1 16.9 16.1 0.8 4.1 48.4 2.4 0.5 14.7 11.5 0.3 0.4 42.0 10.4 1.4 4.4 4.3 0.2 0.0 1.0 1.5 4.4 1.0 3.4 4.0 14.5 1.7 12.9 2.9 15.6 36.1 4.1 5.3 3.5 1.8 5.6 9.7 5.5 14.8 7.1 20.5 6.2 15.1 13.3 10.3 7.1 10.0 7.4 10.0 7.5 3.7 18.6 14.7 9.0 1.5 1.8 0.4 1.5 2.1 1.3 2.1 2.6 4.6 2.1 TPP1 "CLN2, SCAR7" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612763-6619485 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease mutation, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" 13000000 "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavourable (4.31e-4)" "prognostic unfavourable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavourable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" 37.4 64.6 32.2 28.8 36.2 43.0 23.1 15.1 33.3 24.0 26.8 41.7 13.2 28.0 32.0 22.3 20.3 18.0 26.9 25.6 24.5 25.1 36.0 45.1 35.9 42.3 31.0 29.3 22.0 14.8 35.1 30.0 56.4 25.4 19.4 28.2 43.4 18.4 29.1 15.4 15.5 31.4 42.4 32.8 69.0 19.8 17.9 24.7 21.7 24.0 9.1 26.9 25.6 29.4 9.4 43.5 12.8 38.9 7.0 15.3 26.2 4.9 10.1 5.1 9.6 59.4 32.9 3.9 9.8 46.5 7.6 13.3 4.2 21.3 7.2 6.5 24.7 14.9 10.0 13.7 11.6 7.1 5.7 5.8 5.2 11.2 44.9 8.3 35.3 49.3 22.4 8.9 19.8 32.5 11.0 21.6 22.2 6.1 2.6 10.3 3.6 12.2 6.5 4.3 14.0 13.5 7.8 0.6 3.9 10.5 7.8 18.3 5.2 15.9 37.1 22.0 6.3 19.8 3.5 18.3 17.9 2.5 28.0 19.6 11.5 12.8 37.7 8.9 10.7 38.9 8.7 9.4 8.5 11.0 43.5 8.5 5.8 7.6 6.9 7.0 26.4 24.2 15.3 26.2 32.2 36.2 15.1 33.3 24.5 25.1 31.0 29.3 25.4 24.7 TPP2 TPPII ENSG00000134900 "Tripeptidyl peptidase 2" P29144 13 102597003-102679958 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021069, HPA049630" Approved Supported "Nuclear bodies,Cytosol" 410000 "Nuclear bodies, Cytosol" "HPA021069: AB_1858344, HPA049630: " "unprognostic (4.75e-2)" "unprognostic (4.78e-2)" "unprognostic (9.97e-2)" "unprognostic (1.08e-1)" "unprognostic (2.01e-2)" "unprognostic (4.43e-2)" "unprognostic (2.45e-2)" "unprognostic (8.33e-3)" "unprognostic (5.02e-2)" "unprognostic (1.51e-1)" "unprognostic (3.12e-1)" "unprognostic (2.75e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.95e-2)" "unprognostic (3.43e-3)" 19.9 12.4 10.8 21.4 14.5 24.7 18.1 23.1 18.4 16.8 14.7 12.2 50.3 13.1 20.0 21.8 14.4 16.7 13.5 17.0 11.7 9.7 12.9 22.8 18.4 32.8 11.7 13.8 21.6 16.3 15.7 15.7 19.2 15.3 13.9 21.0 12.9 15.6 34.5 35.7 14.1 17.4 19.2 13.4 20.7 15.4 34.5 14.0 23.8 21.9 16.0 19.7 17.0 16.0 6.0 5.8 9.2 6.9 10.9 12.1 4.7 15.9 6.4 18.5 15.7 12.5 17.3 13.2 16.3 11.9 10.5 13.2 13.5 21.5 17.5 5.6 13.1 15.7 14.3 11.5 19.0 12.2 12.7 33.3 16.8 10.8 10.6 37.6 20.3 13.4 5.2 11.8 15.8 15.0 19.8 19.6 14.8 5.0 17.3 28.2 15.0 8.9 19.2 14.0 15.8 13.6 13.2 17.2 14.1 10.2 17.1 7.3 9.8 42.2 12.0 10.0 7.3 6.4 13.5 19.3 23.3 15.3 16.7 27.2 12.9 9.2 6.0 4.0 9.1 6.9 10.7 6.0 10.3 10.1 5.8 5.5 12.1 11.5 1.3 10.9 5.7 4.6 10.9 4.7 10.8 14.5 23.1 18.4 11.7 9.7 11.7 13.8 15.3 14.0 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240696-1242554 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enriched" "Detected in some" 173 "HMC-1: 294.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 308 "basophil: 30.8" "Lineage enriched" "Detected in single" 308 "granulocytes: 30.8" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" "CAB016369: AB_628406, CAB022175: , HPA049153: , HPA049554: " "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favourable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 22.4 0.2 1.6 5.8 1.6 0.0 10.6 1.6 1.6 13.9 17.1 1.6 1.6 17.7 18.7 10.4 15.2 6.1 33.1 4.7 1.6 0.0 4.4 2.8 29.2 16.8 1.6 1.6 2.9 4.5 0.0 1.6 1.9 1.6 24.1 10.0 5.1 14.6 6.3 3.6 29.9 31.0 15.0 1.6 1.6 24.5 5.1 1.6 3.1 3.7 3.8 6.9 21.6 16.0 0.0 0.0 30.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 294.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.6 1.6 1.6 1.6 1.6 0.0 1.6 1.6 1.6 1.6 TPSB2 ENSG00000197253 "Tryptase beta 2 (gene/pseudogene)" P20231 16 1227272-1230184 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.2" "Cell line enriched" "Detected in some" 8 "HMC-1: 81.3" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 84 "basophil: 8.4" "Lineage enriched" "Detected in single" 84 "granulocytes: 8.4" "HPA049153, HPA049554" Supported "Secreted to blood" 7500000 "HPA049153: , HPA049554: " "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 1.8 0.0 0.9 1.9 0.9 0.0 4.1 0.9 0.9 8.8 5.3 0.9 0.9 4.9 2.9 0.9 7.7 0.1 16.2 0.9 0.9 0.9 0.9 12.3 2.4 0.9 0.9 0.9 1.3 0.0 0.9 0.9 0.9 2.7 2.3 0.9 6.2 1.2 0.9 3.4 9.7 4.4 0.9 0.9 13.6 0.9 0.9 0.9 0.9 0.9 0.9 4.2 0.9 0.0 0.0 8.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.1 81.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TPSD1 ENSG00000095917 "Tryptase delta 1" Q9BZJ3 16 1256059-1258998 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 48 "HEL: 18.3;HMC-1: 27.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 65 "basophil: 6.4" "Lineage enriched" "Detected in single" 65 "granulocytes: 6.4" "CAB002215, CAB032871, HPA040182, HPA049554" Supported Uncertain "Nuclear speckles" "Intracellular and membrane" "Nuclear speckles" "CAB002215: AB_563870, CAB032871: AB_2206475, HPA040182: , HPA049554: " "unprognostic (5.99e-2)" "unprognostic (3.00e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (8.97e-3)" "unprognostic (1.15e-4)" "unprognostic (1.70e-1)" "unprognostic (5.45e-2)" "unprognostic (9.00e-2)" "unprognostic (2.88e-1)" "unprognostic (4.30e-1)" "unprognostic (2.94e-2)" "unprognostic (2.50e-3)" "unprognostic (3.74e-2)" "unprognostic (4.14e-1)" "unprognostic (3.89e-1)" "unprognostic (7.46e-3)" 6.6 0.1 0.6 3.8 0.6 0.8 3.7 0.6 0.8 3.2 5.6 0.6 0.6 2.7 7.5 3.3 7.6 2.3 13.0 2.0 0.6 0.0 1.3 2.3 17.0 13.7 0.6 0.6 0.6 0.9 0.1 0.6 0.9 0.6 4.3 0.4 3.1 3.6 0.7 1.6 7.8 9.3 4.7 0.6 0.6 15.7 3.5 0.6 1.6 1.1 2.8 2.6 8.9 6.6 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.1 27.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.8 0.6 0.0 0.6 0.6 0.6 0.6 TPTE "CT44, PTEN2" ENSG00000274391 "Transmembrane phosphatase with tensin homology" P56180 21 10521553-10606140 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 69 "testis: 78.6" "Cell line enhanced" "Detected in some" "BEWO: 7.5;K-562: 8.7;Karpas-707: 7.1;MCF7: 5.2;PC-3: 5.3;RPMI-8226: 9.6;U-2 OS: 4.7;U-266/70: 8.6" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049690, HPA068342" Enhanced Approved "Endoplasmic reticulum,Cytosol" Cytosol "Endoplasmic reticulum" "HPA049690: , HPA068342: " "unprognostic (3.63e-2)" 0.1 0.0 0.0 0.7 0.2 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.8 0.4 0.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.4 0.0 0.9 0.0 78.6 0.0 0.4 0.1 0.4 0.8 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 7.1 0.0 5.2 0.0 0.0 1.2 5.3 0.0 0.0 9.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 4.7 2.4 0.0 8.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 TPTE2 TPIP ENSG00000132958 "Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2" Q6XPS3 13 19422877-19536762 "Enzymes, Plasma proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 12.3" "Group enriched" "Detected in some" 4 "HDLM-2: 9.9;Karpas-707: 2.9" "Cancer enriched" "Detected in single" 6 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA068342 Approved "Endoplasmic reticulum,Cytosol" Cytosol "Endoplasmic reticulum" "HPA068342: " "unprognostic (2.50e-1)" "unprognostic (2.10e-1)" "unprognostic (1.76e-1)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (5.33e-3)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (5.40e-2)" "unprognostic (3.67e-2)" "unprognostic (2.81e-1)" "unprognostic (1.05e-12)" "unprognostic (1.04e-1)" "unprognostic (1.47e-1)" "unprognostic (2.44e-1)" "unprognostic (5.00e-3)" 0.0 0.1 0.4 0.2 1.0 0.0 0.1 0.7 0.8 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.2 12.3 0.0 0.6 0.0 0.0 0.5 0.4 0.0 0.1 0.5 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 9.9 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 2.9 0.0 0.3 0.3 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.1 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 TREH "MGC129621, TRE, TREA" ENSG00000118094 Trehalase O43280 11 118657316-118679690 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 51.8" "Cell line enhanced" "Detected in some" "BEWO: 5.3;Hep G2: 2.1;RPMI-8226: 1.9;SiHa: 1.8;U-2 OS: 2.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039913, HPA042045" Enhanced "Intracellular and membrane" 12000000 "HPA039913: AB_10674988, HPA042045: AB_2677817" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (1.01e-2)" "unprognostic (5.22e-4)" "unprognostic (2.52e-1)" "unprognostic (9.83e-2)" "prognostic favourable (3.76e-4)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (1.63e-2)" "prognostic favourable (2.33e-6)" "unprognostic (2.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.1 24.1 0.0 0.0 28.9 0.1 3.3 0.6 0.1 3.7 0.1 0.1 0.1 6.1 2.6 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.2 0.4 0.0 0.2 0.0 0.1 0.1 51.8 0.0 0.1 0.1 0.6 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.3 5.3 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 1.9 0.0 0.0 0.2 0.9 1.8 0.2 1.4 0.7 0.0 0.8 0.1 2.5 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.0 TREX1 "AGS1, DRN3" ENSG00000213689 "Three prime repair exonuclease 1" Q9NSU2 3 48465811-48467645 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Exonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease mutation, Neurodegeneration, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 31.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035437, HPA046721" Supported Supported Cytosol Cytosol "HPA035437: AB_10672092, HPA046721: " 14.2 14.3 16.7 14.6 10.6 20.7 17.2 13.0 16.9 13.4 11.0 12.8 17.5 10.3 8.1 14.9 16.6 14.5 12.3 9.8 14.4 14.2 11.6 12.7 12.5 26.2 14.6 17.4 7.3 13.0 6.8 31.2 11.6 11.2 15.4 9.3 10.8 32.2 19.3 10.8 22.9 10.9 8.2 12.6 25.5 12.4 4.6 10.1 18.5 7.4 18.3 21.7 13.3 10.6 24.9 35.5 23.3 41.8 8.6 13.1 20.1 8.0 7.4 6.2 4.4 7.7 7.9 0.0 2.6 13.1 22.0 31.0 0.1 9.6 9.5 5.4 11.1 9.4 0.4 11.8 3.1 8.0 0.7 5.5 26.6 0.4 9.7 5.0 3.9 6.9 1.1 11.1 4.4 9.3 0.0 14.6 9.3 0.1 7.0 3.6 0.0 4.6 5.8 1.6 18.6 5.8 1.6 0.0 3.7 9.6 13.0 6.3 0.4 8.4 9.8 4.1 3.9 8.7 6.1 11.8 6.8 4.0 9.1 10.7 3.3 2.1 41.8 3.0 9.8 32.5 5.6 24.6 13.1 9.4 35.5 24.9 12.4 10.3 23.3 8.6 24.3 28.0 11.6 20.1 16.7 10.6 13.0 16.9 14.4 14.2 14.6 17.4 11.2 10.1 TREX2 ENSG00000183479 "Three prime repair exonuclease 2" Q9BQ50 X 153444720-153470587 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 39.6" "Cell line enhanced" "Detected in many" "HEK 293: 7.4;U-698: 10.1;U-937: 9.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.9;eosinophil: 5.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 5.7" "Not detected" "Not detected" HPA054060 Uncertain "HPA054060: " "unprognostic (2.32e-2)" "unprognostic (2.05e-3)" "unprognostic (1.13e-3)" "unprognostic (7.18e-4)" "unprognostic (6.05e-2)" "unprognostic (1.81e-2)" "unprognostic (8.40e-2)" "unprognostic (2.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (1.52e-1)" "unprognostic (9.34e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-2)" 3.2 1.5 2.1 3.4 3.0 1.9 2.1 1.1 3.6 4.3 2.6 1.9 15.5 1.4 2.5 2.2 4.5 2.6 2.2 3.5 1.6 1.2 2.8 4.6 2.4 3.1 2.4 2.4 2.1 2.2 1.5 1.7 2.6 2.7 2.5 1.4 1.4 4.5 7.4 2.0 39.6 2.3 1.9 1.2 4.3 1.7 2.1 1.9 5.8 3.3 6.2 4.7 2.2 5.2 0.4 0.3 5.7 0.1 0.2 0.4 0.2 2.8 3.5 0.3 1.3 0.5 0.7 0.3 0.9 0.8 0.7 2.0 1.0 0.7 0.3 1.8 0.8 3.1 1.2 2.0 0.0 3.1 7.4 0.3 0.7 0.4 0.3 0.8 1.9 0.8 1.8 0.8 0.7 0.3 0.4 3.5 0.2 3.3 2.0 2.2 1.1 2.4 4.8 1.0 2.2 0.3 1.0 0.8 0.4 0.3 0.3 1.0 0.5 0.9 0.0 1.3 2.3 2.8 1.0 3.9 2.7 10.1 0.3 9.4 1.5 3.9 0.0 5.7 0.3 0.0 0.2 0.4 0.1 0.3 0.3 0.3 0.4 0.1 0.0 0.2 0.1 0.0 0.1 0.2 2.1 3.0 1.1 3.6 1.6 1.2 2.4 2.4 2.7 1.9 TRHDE "PAP-II, PGPEP2, TRH-DE" ENSG00000072657 "Thyrotropin releasing hormone degrading enzyme" Q9UKU6 12 72087266-72670757 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.3;pancreas: 19.4" "Cell line enhanced" "Detected in some" "BJ: 20.5;BJ hTERT+: 19.9;EFO-21: 10.7;HBF TERT88: 7.3" "Cancer enhanced" "Detected in some" "renal cancer: 1.9" "Region enhanced" "Detected in many" "cerebellum: 30.3" "Cell type enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" 6200000 "unprognostic (3.56e-2)" "unprognostic (4.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.44e-6)" "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (7.79e-2)" "unprognostic (6.96e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (5.14e-4)" "unprognostic (2.40e-1)" "prognostic favourable (1.53e-7)" "unprognostic (2.55e-2)" "unprognostic (2.48e-1)" "unprognostic (8.91e-3)" "unprognostic (2.94e-2)" 6.2 2.2 2.9 1.0 4.7 1.0 7.6 30.3 12.3 10.2 2.4 0.1 2.5 4.8 2.7 1.7 0.9 2.5 2.5 2.2 7.3 2.8 9.9 1.5 3.0 0.6 1.2 5.5 6.5 19.4 0.4 1.6 0.7 1.5 5.5 1.5 1.0 2.4 5.8 0.7 0.8 4.2 1.2 0.9 4.8 1.1 1.7 0.5 0.0 0.5 0.4 1.0 2.8 7.6 0.2 0.0 1.0 0.3 0.3 0.0 0.0 2.4 0.0 0.4 0.0 1.1 0.0 6.6 20.5 19.9 2.0 1.3 0.0 0.0 0.0 10.7 2.9 0.2 3.7 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.9 0.0 0.0 0.0 6.8 4.5 2.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.1 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 2.9 4.7 30.3 12.3 7.3 2.8 1.2 5.5 1.5 0.5 TWNK "C10orf2, FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL" ENSG00000107815 "Twinkle mtDNA helicase" Q96RR1 10 100987367-100994401 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "Helicase, Hydrolase" "Deafness, Disease mutation, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002532 Uncertain "HPA002532: AB_1078311" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "unprognostic (1.16e-1)" "unprognostic (2.19e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (7.82e-3)" "unprognostic (7.99e-2)" "unprognostic (1.22e-1)" "unprognostic (7.95e-2)" "unprognostic (7.52e-2)" "unprognostic (1.96e-2)" "unprognostic (9.46e-2)" "unprognostic (9.82e-3)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" 8.5 12.1 8.4 11.1 9.9 4.2 12.6 8.7 10.4 6.1 7.3 6.0 2.6 5.4 9.1 9.0 10.1 11.4 6.6 8.4 8.7 5.1 8.4 10.8 4.4 9.6 10.6 7.4 9.8 14.7 9.5 11.1 6.4 9.4 7.7 8.3 3.9 6.8 5.9 32.5 9.6 6.8 7.4 12.2 10.4 7.0 15.0 10.9 12.6 8.9 9.8 13.1 6.6 14.1 5.4 2.4 1.1 1.5 4.7 7.8 2.5 6.4 13.6 5.4 17.2 5.0 3.4 6.5 4.7 6.4 7.7 7.6 22.4 5.7 23.3 9.3 2.9 10.8 22.7 11.8 9.7 10.8 13.4 17.6 8.0 17.2 8.4 22.5 7.3 6.7 13.6 11.2 35.2 4.7 18.9 6.5 5.3 8.8 15.3 8.2 15.6 11.4 14.9 12.0 14.2 5.0 6.6 8.8 17.0 5.1 7.0 17.0 9.1 7.7 5.3 3.8 7.8 4.7 13.9 12.2 12.6 19.9 4.6 20.7 4.2 1.1 1.1 0.1 2.6 0.9 7.8 5.4 3.8 5.0 2.1 4.0 4.1 4.5 0.0 4.7 1.5 2.4 1.0 2.5 8.4 9.9 8.7 10.4 8.7 5.1 10.6 7.4 9.4 10.9 UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655675-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.5;lymphoid tissue: 27.7" "Cell line enhanced" "Detected in many" "HEL: 41.7;HMC-1: 31.7;hTEC/SVTERT24-B: 25.9;REH: 24.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebellum: 32.5;pons and medulla: 21.2" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038605, HPA038607" Approved Approved "Plasma membrane" 2200000 "Plasma membrane" "HPA038605: AB_10669648, HPA038607: " "unprognostic (4.94e-2)" "unprognostic (6.03e-3)" "unprognostic (1.34e-1)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.09e-2)" "unprognostic (4.67e-3)" "unprognostic (1.21e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (6.20e-2)" "unprognostic (9.02e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (2.72e-3)" "unprognostic (1.53e-1)" 4.3 1.3 2.8 5.5 4.0 7.2 1.5 32.5 4.9 4.0 1.5 0.7 0.0 1.7 1.3 0.3 1.8 1.1 2.4 1.3 3.4 3.5 1.5 1.7 5.5 10.9 5.1 1.9 0.8 1.2 0.6 0.9 16.8 21.2 1.3 1.8 0.9 1.3 0.9 1.8 4.1 2.4 2.3 2.1 27.7 1.7 2.1 0.2 23.9 2.9 1.7 3.8 3.4 1.3 1.0 1.7 9.8 11.0 6.5 4.9 1.8 4.4 10.9 2.0 2.6 0.8 1.6 10.3 15.8 8.8 6.4 5.0 4.3 2.4 1.8 1.2 8.4 2.2 0.0 5.6 10.3 0.0 0.3 41.7 0.3 3.6 2.4 5.0 31.7 1.4 0.3 25.9 9.6 4.3 0.0 0.0 6.2 0.1 6.1 3.2 0.8 2.6 24.9 1.2 0.2 10.2 3.8 4.5 0.1 4.2 0.3 3.5 0.0 1.3 11.2 8.4 4.5 4.9 6.5 0.3 0.0 5.3 4.4 7.1 15.2 0.0 1.3 9.8 2.0 6.5 2.2 0.3 2.6 1.8 1.7 1.0 3.0 1.6 2.8 6.5 11.0 0.2 4.9 1.8 2.8 4.0 32.5 4.9 3.4 3.5 5.1 1.9 21.2 0.2 UBLCP1 "CPUB1, MGC10067" ENSG00000164332 "Ubiquitin like domain containing CTD phosphatase 1" Q8WVY7 5 159263081-159286040 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039615 Approved Supported Nucleoplasm,Nucleoli Nucleoli Nucleoplasm "HPA039615: AB_10674425" "unprognostic (1.25e-1)" "unprognostic (3.10e-1)" "unprognostic (6.04e-3)" "unprognostic (3.45e-2)" "unprognostic (7.08e-2)" "unprognostic (6.82e-2)" "prognostic unfavourable (4.46e-5)" "unprognostic (4.01e-1)" "unprognostic (2.14e-2)" "unprognostic (1.98e-1)" "unprognostic (1.91e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (2.51e-2)" 17.1 16.0 16.7 18.4 19.7 16.7 16.3 20.2 33.0 18.5 12.5 12.2 11.4 9.8 22.5 13.1 22.2 14.7 14.5 13.1 20.9 19.1 17.5 14.4 17.8 24.1 19.7 22.7 16.8 12.6 18.0 23.9 19.6 36.7 14.7 14.7 10.9 15.4 17.6 15.3 14.2 13.8 19.5 20.4 22.2 13.3 24.2 15.4 26.8 14.4 16.1 30.1 18.8 16.8 11.9 10.8 21.9 13.9 25.5 19.2 8.2 14.5 10.6 22.0 23.8 22.9 21.2 13.0 15.9 24.2 16.3 21.8 8.6 10.1 13.0 17.6 19.8 11.1 13.6 30.5 28.5 25.9 13.3 10.0 9.3 7.8 28.9 22.6 15.8 18.7 28.7 14.8 29.6 15.5 13.7 17.6 22.7 4.7 12.2 6.9 15.2 6.4 15.5 21.5 15.2 16.1 11.2 11.7 15.5 16.0 10.7 37.4 11.3 15.1 16.5 16.8 14.1 8.7 20.0 14.1 14.2 19.8 17.8 15.6 24.9 21.9 6.5 16.1 16.6 13.5 18.6 11.9 15.8 17.3 8.5 10.9 18.5 19.2 19.4 25.5 13.9 10.8 16.9 8.2 16.7 19.7 20.2 33.0 20.9 19.1 19.7 22.7 36.7 15.4 UCHL1 "PARK5, PGP9.5, Uch-L1" ENSG00000154277 "Ubiquitin C-terminal hydrolase L1" P09936 4 41256413-41268455 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 225.8" "Cell line enhanced" "Detected in many" "EFO-21: 97.1;SCLC-21H: 96.9;U-251 MG: 88.7;U-266/84: 85.5;U-87 MG: 94.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 3.6" "Lineage enriched" "Detected in single" 37 "B-cells: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002580, HPA005993, CAB079024" Enhanced Supported Supported Nucleoplasm,Cytosol 440000 Cytosol Nucleoplasm "CAB002580: AB_563981, CAB079024: , HPA005993: AB_1858560" "unprognostic (1.54e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-1)" "prognostic unfavourable (4.08e-5)" "unprognostic (2.34e-1)" "unprognostic (1.98e-1)" "unprognostic (6.28e-3)" "unprognostic (1.09e-2)" "unprognostic (4.31e-2)" "unprognostic (8.77e-3)" "unprognostic (3.56e-3)" "unprognostic (3.70e-2)" "unprognostic (1.82e-3)" "unprognostic (1.24e-2)" "unprognostic (7.12e-3)" "unprognostic (2.10e-2)" "prognostic unfavourable (1.93e-4)" 8.2 40.2 52.4 8.9 65.1 2.0 3.1 17.5 225.8 4.5 6.3 11.5 0.0 5.5 6.0 1.8 2.7 5.7 6.5 5.4 53.4 97.4 14.0 2.0 2.7 6.5 62.0 57.1 15.4 6.3 1.8 30.5 2.7 100.6 5.3 4.7 6.0 3.0 4.4 7.5 2.7 8.6 5.2 38.6 2.3 2.8 8.0 8.3 0.0 3.9 0.0 4.5 5.6 2.8 3.6 0.0 0.0 0.0 0.0 0.0 0.6 0.2 55.0 11.4 0.0 1.5 1.9 0.0 57.6 29.7 20.4 20.6 11.1 0.0 0.0 97.1 29.3 0.1 21.0 0.0 8.3 0.1 8.6 0.0 0.3 0.0 44.0 0.0 0.0 10.6 0.2 16.3 0.0 0.1 0.0 0.2 10.8 0.0 0.0 0.9 32.9 62.2 0.0 24.4 0.0 30.8 0.0 96.9 60.9 0.3 0.2 0.1 0.0 0.4 0.3 1.3 0.4 0.0 88.7 45.5 85.5 0.2 94.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 52.4 65.1 17.5 92.6 53.4 97.4 62.0 57.1 100.6 8.3 UCHL3 ENSG00000118939 "Ubiquitin C-terminal hydrolase L3" P15374 13 75549480-75606020 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019678, CAB037139, CAB037208" Approved Supported Nucleoplasm,Cytosol 490000 "Nucleoplasm, Cytosol" "CAB037139: AB_1841234, CAB037208: AB_1841235, HPA019678: AB_1858583" "unprognostic (4.16e-1)" "unprognostic (3.84e-2)" "unprognostic (8.83e-3)" "unprognostic (1.14e-1)" "unprognostic (5.15e-2)" "unprognostic (6.46e-3)" "prognostic unfavourable (6.41e-4)" "unprognostic (1.19e-1)" "unprognostic (5.59e-2)" "unprognostic (9.71e-2)" "unprognostic (1.24e-1)" "unprognostic (7.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.97e-1)" "unprognostic (2.76e-2)" "unprognostic (8.84e-2)" "unprognostic (3.26e-2)" 13.7 39.1 23.6 11.9 37.6 17.4 21.4 17.5 18.7 10.6 21.2 11.4 12.8 12.8 9.0 40.5 37.7 8.1 12.4 15.5 20.6 12.6 20.7 36.8 10.3 12.2 18.2 13.5 7.7 20.8 9.5 28.9 26.3 14.7 12.4 25.0 6.1 24.0 14.9 31.7 28.8 15.0 16.9 13.3 15.3 14.5 24.6 18.6 18.9 28.1 29.8 20.2 16.0 16.2 17.4 46.0 15.8 43.5 20.5 23.4 17.3 53.2 8.9 7.8 5.4 14.6 17.4 22.5 20.2 20.0 26.3 29.5 49.3 25.9 27.6 14.6 21.2 29.4 18.2 49.0 40.0 14.7 15.9 17.4 14.8 31.5 21.1 41.5 13.1 15.5 34.1 20.5 33.1 25.6 19.0 7.9 39.5 19.2 16.8 27.2 11.6 26.9 13.5 12.6 18.1 30.9 21.7 23.5 6.9 11.5 22.4 9.3 12.9 11.8 19.8 11.5 13.7 12.2 26.9 11.1 12.3 32.1 23.2 45.0 8.2 15.6 24.1 15.8 10.9 43.5 14.2 17.4 19.9 15.5 33.6 16.0 19.8 18.3 5.4 20.5 36.2 46.0 23.4 17.3 23.6 37.6 17.5 18.7 20.6 12.6 18.2 13.5 14.7 18.6 UCHL5 "CGI-70, INO80R, UCH37" ENSG00000116750 "Ubiquitin C-terminal hydrolase L5" Q9Y5K5 1 193012250-193060080 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005908, HPA075383" Approved Supported Nucleoplasm,Mitochondria "Nucleoplasm, Mitochondria" "HPA005908: AB_1858585, HPA075383: " "unprognostic (3.66e-2)" "unprognostic (3.84e-3)" "unprognostic (5.17e-2)" "unprognostic (5.98e-2)" "unprognostic (1.20e-2)" "unprognostic (1.20e-1)" "unprognostic (3.50e-2)" "unprognostic (7.41e-2)" "unprognostic (1.96e-2)" "unprognostic (1.04e-3)" "unprognostic (3.44e-3)" "unprognostic (6.92e-2)" "unprognostic (6.41e-3)" "unprognostic (1.51e-1)" "unprognostic (7.15e-2)" "prognostic unfavourable (7.10e-5)" "unprognostic (4.33e-2)" 15.7 18.3 20.1 16.1 26.2 16.0 18.2 30.1 34.8 10.9 17.7 11.5 12.6 19.0 12.5 14.7 26.1 10.7 11.9 22.0 21.6 20.6 21.6 28.3 12.4 19.9 21.3 29.4 13.4 24.8 15.6 16.2 17.8 33.3 17.8 18.8 10.3 19.3 12.9 29.1 16.7 18.0 13.9 20.1 17.3 14.0 9.9 17.5 20.0 15.1 19.1 23.0 14.8 14.8 22.5 20.8 23.8 21.1 35.6 30.9 20.9 33.2 18.5 16.0 16.4 9.3 9.5 19.1 19.6 10.0 18.8 16.3 17.4 22.6 26.1 18.9 10.8 20.7 21.3 25.3 24.9 26.9 15.3 30.9 23.9 23.1 15.0 48.5 17.4 8.7 11.3 26.9 23.9 18.5 67.7 21.3 15.9 26.8 35.7 18.0 14.8 11.7 20.7 18.0 50.7 17.5 19.5 16.3 20.1 17.6 25.5 27.2 20.7 24.5 12.0 17.6 5.4 17.8 31.1 16.6 25.6 29.4 10.5 30.3 29.9 23.8 16.5 19.0 28.3 19.5 30.9 22.5 25.9 26.9 19.4 18.0 28.2 30.5 10.0 35.6 21.1 20.8 24.8 20.9 20.1 26.2 30.1 34.8 21.6 20.6 21.3 29.4 33.3 17.5 UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097574-109110992 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB011605 Uncertain Approved Cytosol Cytosol "CAB011605: AB_778737" "unprognostic (4.38e-2)" "unprognostic (3.82e-3)" "unprognostic (1.03e-2)" "unprognostic (1.33e-2)" "unprognostic (4.64e-1)" "unprognostic (4.10e-2)" "prognostic unfavourable (6.40e-4)" "unprognostic (5.68e-3)" "prognostic unfavourable (3.06e-4)" "unprognostic (4.66e-2)" "unprognostic (8.78e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.57e-2)" "unprognostic (4.50e-1)" "unprognostic (1.40e-2)" "unprognostic (6.89e-2)" 16.3 44.1 17.0 19.4 17.0 10.0 22.8 10.5 14.4 13.5 20.3 10.2 21.4 12.6 11.8 10.8 22.5 11.8 11.0 15.4 13.5 13.1 20.4 23.3 7.1 12.1 19.6 12.2 12.3 12.7 17.3 8.9 18.6 12.0 12.9 22.1 10.7 16.6 19.7 29.1 22.5 13.5 11.0 19.7 13.2 12.3 35.6 9.8 35.1 25.1 19.8 19.0 11.5 14.4 9.8 3.9 5.8 3.0 8.7 19.5 7.9 20.0 20.6 19.8 18.0 33.1 9.5 19.0 11.9 8.1 18.8 14.4 16.3 13.8 26.3 17.9 10.6 12.7 21.9 12.3 18.3 22.3 40.7 25.7 11.9 27.6 4.9 38.2 15.9 8.5 11.3 9.0 5.0 13.5 20.8 8.8 12.6 25.0 35.1 45.1 35.3 31.8 32.3 29.9 22.4 11.7 25.3 28.3 15.7 21.3 18.4 10.3 34.2 17.9 6.9 16.3 14.6 10.7 16.4 17.2 37.0 50.0 12.4 25.7 19.8 5.8 1.5 2.7 13.4 3.0 19.5 9.8 15.9 15.5 3.9 9.2 10.3 11.5 0.0 8.7 3.0 2.8 14.0 7.9 17.0 17.0 10.5 14.4 13.5 13.1 19.6 12.2 12.0 9.8 UPB1 BUP1 ENSG00000100024 "Beta-ureidopropionase 1" Q9UBR1 22 24494107-24528390 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 85.7" "Group enriched" "Detected in some" 5 "CACO-2: 10.9;NB-4: 4.5;THP-1: 6.0;U-937: 6.8" "Cancer enriched" "Detected in some" 8 "liver cancer: 25.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "basophil: 11.4;neutrophil: 3.0" "Lineage enriched" "Detected in single" 43 "granulocytes: 11.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA000728 Enhanced 790000 "HPA000728: AB_1080471" "unprognostic (7.27e-2)" "unprognostic (4.57e-3)" "unprognostic (2.27e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (1.09e-4)" "prognostic favourable (2.30e-7)" "unprognostic (8.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.93e-1)" "unprognostic (4.89e-6)" "unprognostic (3.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (1.99e-1)" "unprognostic (4.63e-3)" 0.1 0.0 0.1 0.1 0.2 1.0 0.1 0.1 0.1 0.1 1.1 0.1 0.1 0.6 0.1 0.5 0.1 0.0 0.1 0.5 0.1 0.0 13.5 85.7 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.2 0.2 1.5 0.1 0.1 0.2 0.0 0.8 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 11.4 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 10.9 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 1.2 0.0 0.3 1.1 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.4 0.3 0.1 0.0 0.2 1.1 1.3 0.3 0.0 0.0 6.0 0.5 0.1 0.1 0.0 0.0 1.1 0.0 1.3 1.3 6.8 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 3.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 USP1 ENSG00000162607 "Ubiquitin specific peptidase 1" O94782 1 62436297-62451804 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.6" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028387, HPA028440" Approved Supported Nucleoplasm Nucleoplasm "HPA028387: , HPA028440: AB_10603000" "unprognostic (1.22e-1)" "unprognostic (5.36e-2)" "unprognostic (1.78e-3)" "unprognostic (4.05e-3)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "prognostic unfavourable (5.81e-5)" "unprognostic (6.72e-2)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.33e-3)" "unprognostic (3.99e-2)" "unprognostic (2.76e-2)" "unprognostic (9.61e-3)" "unprognostic (5.70e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" 11.6 9.0 11.3 17.2 10.7 29.3 15.9 20.6 14.2 19.2 13.3 7.8 8.0 10.8 15.1 12.0 15.6 13.8 8.9 9.0 11.5 9.6 11.8 9.3 11.7 19.2 14.2 9.6 26.7 12.7 14.8 18.4 13.6 10.9 14.8 13.9 7.6 12.7 13.5 11.7 12.3 13.3 15.8 15.5 18.1 11.6 31.6 11.8 70.6 15.0 13.3 20.1 16.5 16.5 14.7 11.8 23.4 12.4 15.5 16.3 9.2 22.0 6.5 27.4 14.8 6.2 7.4 15.2 21.2 14.5 26.4 29.0 11.0 10.8 39.9 15.4 11.9 12.8 22.5 14.6 37.0 19.9 16.2 32.7 22.6 11.5 6.7 35.0 16.5 3.9 9.6 23.9 18.0 12.4 23.7 34.9 18.6 9.8 35.9 13.5 24.1 13.5 34.1 46.5 24.7 9.9 16.5 28.4 15.9 24.0 19.6 23.2 11.2 21.4 8.6 20.4 22.2 29.8 29.7 13.9 19.3 45.8 13.8 28.0 18.2 17.4 9.5 23.4 12.6 9.6 16.3 14.7 15.0 12.7 11.4 10.7 14.3 11.9 16.9 15.5 12.4 11.8 13.6 9.2 11.3 10.7 20.6 14.2 11.5 9.6 14.2 9.6 10.9 11.8 USP10 "KIAA0190, UBPO" ENSG00000103194 "Ubiquitin specific peptidase 10" Q14694 16 84699978-84779922 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 105.5" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "neutrophil: 105.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 105.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006731, HPA006749" Enhanced Enhanced Nucleoplasm,Cytosol Cytosol Nucleoplasm "HPA006731: AB_1080495, HPA006749: AB_1080492" "unprognostic (4.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.36e-2)" "unprognostic (4.85e-2)" "unprognostic (6.93e-2)" "unprognostic (1.77e-3)" "unprognostic (1.03e-3)" "unprognostic (2.91e-3)" "unprognostic (1.75e-1)" "unprognostic (3.84e-2)" "unprognostic (2.56e-2)" "unprognostic (1.82e-3)" "prognostic favourable (1.00e-4)" "unprognostic (5.91e-2)" "unprognostic (4.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.38e-1)" 13.9 18.8 16.0 24.2 19.0 13.4 14.4 24.4 20.4 15.9 18.1 15.6 8.4 16.1 20.2 10.4 19.7 18.2 12.0 16.4 19.3 15.1 16.4 20.7 13.7 18.8 19.7 17.4 18.5 17.1 35.8 15.0 23.5 16.2 15.0 15.6 17.9 15.3 17.8 47.0 17.0 17.5 20.2 16.3 16.0 15.0 15.5 16.2 20.4 17.6 15.7 20.9 19.7 15.8 7.2 10.4 105.5 8.6 7.7 17.3 10.0 13.6 18.9 18.4 22.8 6.8 11.6 24.9 13.5 14.3 22.9 12.6 26.6 11.9 23.7 15.7 14.1 15.7 25.5 21.5 30.5 9.6 13.4 13.6 8.9 17.6 9.0 20.2 8.3 7.3 16.6 23.9 27.7 17.5 37.1 5.2 15.8 28.6 20.9 9.8 22.1 12.8 27.2 10.1 11.2 14.4 11.1 17.2 10.1 32.3 10.5 9.1 24.1 12.9 12.8 15.9 12.7 8.0 12.8 8.7 12.1 60.1 10.3 13.0 16.3 2.5 8.6 1.6 5.7 7.0 6.8 7.2 17.3 6.3 10.4 6.7 9.9 6.0 105.5 7.7 6.3 3.5 6.1 10.0 16.0 19.0 24.4 20.4 19.3 15.1 19.7 17.4 16.2 16.2 USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232690-47248328 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 74.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA003103: AB_10671088, HPA037536: AB_10672904" "unprognostic (1.60e-1)" "unprognostic (2.77e-3)" "unprognostic (5.84e-2)" "prognostic unfavourable (2.95e-4)" "unprognostic (3.08e-2)" "unprognostic (2.02e-1)" "unprognostic (6.11e-3)" "unprognostic (9.21e-2)" "unprognostic (3.18e-2)" "unprognostic (3.52e-1)" "unprognostic (3.29e-3)" "unprognostic (3.74e-2)" "prognostic favourable (4.13e-5)" "unprognostic (3.14e-2)" "unprognostic (9.23e-2)" "unprognostic (9.51e-2)" "unprognostic (7.11e-2)" 11.5 17.3 32.9 11.5 55.0 4.9 9.4 35.7 74.0 17.5 9.1 19.9 5.8 6.0 22.6 12.7 9.7 26.6 12.8 20.6 27.0 44.0 13.6 6.7 12.5 13.8 23.1 47.4 38.2 13.8 28.4 32.3 12.6 27.8 15.7 7.6 17.9 9.3 21.3 13.7 7.8 7.3 19.1 17.0 13.5 9.1 19.2 14.6 19.0 27.2 4.3 14.3 11.0 9.8 21.0 20.6 22.8 8.7 19.8 31.7 16.4 14.3 22.6 38.9 26.5 14.7 9.9 10.8 11.0 17.3 21.9 24.5 21.5 11.8 9.5 8.7 19.8 17.1 31.5 7.7 19.5 14.7 23.9 11.1 17.9 19.1 17.1 12.4 23.2 14.2 3.2 23.1 9.9 8.7 8.3 1.3 17.0 21.8 24.1 13.3 28.9 20.2 27.2 38.1 7.9 10.7 19.8 22.0 37.8 20.1 4.1 11.9 8.5 7.2 9.1 18.5 19.5 26.0 12.5 17.7 11.1 16.6 11.4 15.5 16.4 22.8 3.5 7.4 22.6 7.4 19.9 20.1 10.2 22.1 4.6 21.0 15.4 31.7 2.2 19.8 8.7 20.6 12.7 16.4 32.9 55.0 35.7 74.0 27.0 44.0 23.1 47.4 27.8 14.6 USP12 USP12L1 ENSG00000152484 "Ubiquitin specific peptidase 12" O75317 13 27066142-27171896 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, HPA059492" Uncertain Approved Nucleoplasm Nucleoplasm "HPA007288: AB_1080531, HPA059492: " "unprognostic (6.72e-3)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (5.85e-2)" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "unprognostic (8.38e-2)" "unprognostic (8.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.91e-1)" "unprognostic (6.77e-2)" "unprognostic (1.73e-1)" 15.7 10.4 18.3 23.3 17.8 46.0 15.6 16.6 18.3 12.1 30.6 16.1 8.8 13.0 15.3 11.6 23.5 9.5 14.5 11.3 19.3 15.9 18.3 27.9 19.9 19.6 20.5 7.5 12.0 13.4 10.7 16.2 14.8 12.4 17.5 19.1 10.1 8.9 9.5 9.8 17.3 33.0 43.8 18.5 16.5 14.7 11.0 13.1 8.4 12.0 6.6 18.5 42.8 24.2 4.6 3.0 5.3 2.1 2.3 3.6 1.2 12.0 7.6 14.6 7.5 9.8 12.5 5.2 17.0 12.0 9.5 7.1 13.7 19.0 17.2 8.6 13.4 7.5 9.5 9.9 20.3 27.7 8.2 26.6 9.9 9.6 12.3 15.3 18.7 7.8 14.5 10.7 12.3 21.8 8.8 8.4 19.6 7.0 9.4 20.5 10.4 13.5 10.8 18.6 4.0 18.7 8.6 16.1 9.7 14.6 12.3 13.8 5.8 15.0 25.7 9.9 9.6 21.2 15.4 6.4 7.1 12.3 16.7 9.2 11.0 0.0 1.2 5.3 1.5 1.3 2.5 3.2 2.4 2.0 1.6 4.6 1.6 1.7 1.2 2.3 2.1 3.0 3.6 1.2 18.3 17.8 16.6 15.5 19.3 15.9 20.5 7.5 12.4 13.1 USP13 IsoT-3 ENSG00000058056 "Ubiquitin specific peptidase 13" Q92995 3 179652755-179789401 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 34.8;skeletal muscle: 90.3" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "MAIT T-cell: 15.4" "Lineage enriched" "Detected in many" 8 "T-cells: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004827 Enhanced Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA004827: AB_1080497" "unprognostic (1.00e-2)" "unprognostic (2.09e-1)" "unprognostic (5.82e-2)" "unprognostic (7.14e-2)" "unprognostic (9.94e-2)" "unprognostic (3.96e-2)" "prognostic unfavourable (2.40e-5)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (7.79e-2)" "unprognostic (1.69e-3)" "unprognostic (2.22e-2)" "prognostic unfavourable (3.46e-6)" "unprognostic (4.93e-2)" "unprognostic (9.79e-2)" "unprognostic (3.38e-2)" "prognostic unfavourable (3.06e-4)" 6.4 7.5 2.0 2.3 2.8 0.8 3.5 2.9 4.1 2.7 2.1 4.6 1.5 0.7 3.2 3.8 2.6 2.5 2.5 34.8 2.0 2.3 2.3 3.4 6.0 2.5 2.1 2.1 7.2 3.0 3.3 9.8 1.9 3.0 3.0 1.8 3.1 3.3 2.1 90.3 1.8 1.7 3.7 2.5 1.6 1.6 5.6 1.3 1.7 5.5 17.1 3.2 2.6 1.9 2.0 1.9 0.0 0.4 0.0 15.4 0.7 12.3 5.3 10.1 7.7 4.6 6.4 4.9 7.3 8.4 10.8 9.1 7.8 4.4 15.3 8.2 8.8 0.9 11.3 4.4 12.9 36.2 4.8 4.0 8.0 7.3 3.3 11.2 0.0 6.8 1.6 8.4 10.7 8.6 1.9 19.8 8.9 8.1 6.8 2.0 7.8 4.8 11.7 10.0 12.5 7.3 3.5 5.7 7.4 7.0 9.4 4.2 16.2 8.1 9.3 13.0 10.4 11.1 28.1 9.6 8.0 31.4 6.0 7.6 12.1 0.0 0.2 0.0 1.3 0.4 15.4 2.0 1.3 2.9 1.5 0.6 1.0 1.0 0.0 0.0 0.4 1.9 0.6 0.7 2.0 2.8 2.9 4.1 2.0 2.3 2.1 2.1 3.0 1.3 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported Cytosol 1400000 Cytosol "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavourable (7.81e-5)" "prognostic unfavourable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favourable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 24.8 24.2 25.9 20.7 32.1 19.4 21.7 21.7 28.4 16.5 17.1 17.9 19.1 13.4 19.4 24.3 25.3 14.7 14.4 23.3 22.1 27.6 23.2 24.4 15.8 21.9 22.6 28.8 16.2 16.2 22.3 18.0 25.1 29.2 29.9 19.4 14.5 16.7 20.5 53.3 15.7 12.9 23.9 22.1 15.4 15.6 17.2 16.5 19.5 20.1 25.4 28.6 17.8 17.8 13.1 15.2 7.7 15.2 23.0 21.2 11.0 26.8 22.1 18.8 19.1 18.7 18.7 33.7 35.3 19.4 36.0 33.6 28.7 14.4 39.9 27.0 28.9 15.1 37.1 27.0 41.1 11.3 18.3 22.5 14.8 22.5 18.7 55.2 21.6 14.9 20.9 36.7 21.1 27.6 31.0 29.7 35.4 21.8 30.8 15.1 18.4 26.0 25.7 24.7 29.1 26.6 23.3 22.0 18.5 36.6 17.7 15.0 17.3 14.9 31.2 42.3 32.0 38.8 50.0 19.6 35.6 39.7 24.4 23.0 26.3 5.0 10.7 7.7 17.8 15.2 21.2 13.1 17.7 18.4 15.2 10.1 17.5 16.9 0.8 23.0 11.4 11.1 16.7 11.0 25.9 32.1 21.7 27.1 22.1 27.6 22.6 28.8 29.2 16.5 USP15 "KIAA0529, UNPH4" ENSG00000135655 "Ubiquitin specific peptidase 15" Q9Y4E8 12 62260338-62417431 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.9" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 68.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006237, HPA006428, HPA071014" Approved Enhanced Cytosol 280000 Cytosol "HPA006237: AB_1080502, HPA006428: , HPA071014: " "unprognostic (8.18e-2)" "unprognostic (3.22e-1)" "unprognostic (9.63e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.75e-1)" "prognostic unfavourable (8.04e-4)" "unprognostic (6.59e-2)" "unprognostic (7.70e-3)" "unprognostic (2.19e-1)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "prognostic unfavourable (1.58e-5)" "unprognostic (9.28e-2)" "unprognostic (5.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" 23.1 16.8 11.5 22.5 11.9 88.9 17.8 21.1 15.7 14.5 14.5 5.2 11.9 11.4 12.7 12.4 16.1 14.1 11.2 15.2 9.6 6.2 13.8 20.4 23.8 26.2 11.6 9.4 22.5 15.8 18.9 22.5 31.0 14.9 12.4 13.8 7.6 16.2 10.7 28.5 23.0 19.7 16.3 16.2 35.6 14.3 20.0 11.0 33.1 14.1 15.4 18.9 18.4 17.9 5.7 6.0 68.5 14.2 3.3 12.1 4.8 9.3 8.8 8.8 7.6 13.9 16.3 15.7 15.2 13.5 13.5 12.1 8.8 9.4 10.0 8.7 13.0 10.2 11.7 13.2 15.8 11.0 7.2 13.7 7.5 6.7 13.5 21.7 33.4 11.8 13.8 15.9 14.2 15.9 44.4 19.4 12.4 10.4 12.9 11.0 12.9 13.0 8.3 9.3 16.1 12.5 10.8 11.1 5.3 17.6 11.2 8.6 14.7 13.0 19.0 10.5 10.5 16.3 9.4 9.2 10.2 11.4 12.0 17.7 11.8 27.2 14.2 13.8 3.4 7.3 3.5 5.7 4.6 3.2 4.9 4.7 5.9 3.5 68.5 3.3 5.8 6.0 12.1 4.8 11.5 11.9 21.1 15.7 9.6 6.2 11.6 9.4 14.9 11.0 USP16 Ubp-M ENSG00000156256 "Ubiquitin specific peptidase 16" Q9Y5T5 21 29024629-29054488 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021140 Supported Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA021140: AB_1858668" "unprognostic (6.06e-2)" "unprognostic (3.14e-1)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (5.92e-2)" "unprognostic (5.79e-3)" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (5.78e-2)" "unprognostic (7.40e-2)" "unprognostic (8.73e-2)" "unprognostic (8.65e-2)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (1.55e-1)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" 25.4 21.7 24.4 27.4 24.2 20.4 22.8 32.4 23.1 24.2 24.3 13.5 23.6 20.4 22.6 28.2 27.1 19.4 17.0 23.8 23.8 22.6 28.4 34.0 16.8 20.7 25.8 19.5 27.3 23.6 31.6 41.6 45.9 25.3 26.0 22.3 13.3 20.6 28.8 35.8 16.1 33.2 26.2 28.6 29.1 20.8 20.1 25.3 37.6 28.4 25.6 25.5 30.8 17.1 30.9 23.5 21.2 20.5 19.9 26.2 10.1 21.8 8.7 13.9 12.5 9.9 16.3 13.1 21.3 14.2 14.8 14.1 10.9 14.2 22.3 6.5 20.4 10.0 17.2 15.5 19.4 21.3 18.3 29.7 10.6 12.1 14.7 29.1 16.5 13.9 16.4 19.3 17.8 14.2 24.4 39.4 17.1 10.0 17.9 10.6 14.8 11.3 12.0 34.3 25.5 12.2 15.8 15.1 16.1 13.8 22.1 18.7 15.2 20.0 14.2 17.3 21.6 15.9 21.9 33.7 46.2 23.4 18.1 21.2 17.2 21.2 16.2 20.9 25.4 16.1 19.8 26.4 23.9 22.8 14.9 30.9 26.2 24.8 15.5 19.9 20.5 23.5 24.5 10.1 24.4 24.2 32.4 23.1 23.8 22.6 25.8 19.5 25.3 25.3 USP17L1 USP17L1P ENSG00000230549 "Ubiquitin specific peptidase 17-like family member 1" Q7RTZ2 8 7332387-7333979 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in single" "brain: 2.1" "Cell line enhanced" "Detected in single" "AN3-CA: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L10 ENSG00000231396 "Ubiquitin specific peptidase 17-like family member 10" C9JJH3 4 9210657-9212608 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L11 ENSG00000233136 "Ubiquitin specific peptidase 17-like family member 11" C9JVI0 4 9215405-9217356 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "blood: 1.0;fallopian tube: 1.2;thyroid gland: 1.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.5;NTERA-2: 1.6" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 11 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 11 "dendritic cells: 1.0" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 USP17L12 ENSG00000227551 "Ubiquitin specific peptidase 17-like family member 12" C9JPN9 4 9220152-9221744 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L13 ENSG00000232399 "Ubiquitin specific peptidase 17-like family member 13" C9JLJ4 4 9224896-9226847 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L15 ENSG00000223569 "Ubiquitin specific peptidase 17-like family member 15" C9J2P7 4 9234385-9236334 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "brain: 1.0;epididymis: 1.0" "Cell line enhanced" "Detected in single" "U-87 MG: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.2 1.0 0.0 0.3 0.0 0.1 0.3 0.4 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L17 ENSG00000249104 "Ubiquitin specific peptidase 17-like family member 17" D6RBQ6 4 9243879-9245830 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in single" "thyroid gland: 1.0" "Cell line enhanced" "Detected in some" "HDLM-2: 1.2;NTERA-2: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L18 ENSG00000250844 "Ubiquitin specific peptidase 17-like family member 18" D6R9N7 4 9248630-9250581 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L19 ENSG00000248920 "Ubiquitin specific peptidase 17-like family member 19" D6RCP7 4 9253378-9255329 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L2 DUB3 ENSG00000223443 "Ubiquitin specific peptidase 17-like family member 2" Q6R6M4 8 12137168-12139077 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell line enhanced" "Detected in single" "HEK 293: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " "unprognostic (2.01e-1)" 0.1 0.4 0.1 0.1 0.5 0.0 0.2 0.8 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 1.0 1.1 0.0 0.3 0.1 0.1 0.4 0.0 0.1 0.1 0.1 0.1 0.6 0.1 0.1 0.1 0.2 0.0 0.5 0.1 0.1 0.2 0.1 0.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.1 0.1 0.0 0.1 0.1 0.1 0.1 USP17L20 ENSG00000250745 "Ubiquitin specific peptidase 17-like family member 20" D6RJB6 4 9258124-9260075 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTERT-HME1: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L21 ENSG00000249811 "Ubiquitin specific peptidase 17-like family member 21" D6R901 4 9262872-9264823 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L22 ENSG00000248933 "Ubiquitin specific peptidase 17-like family member 22" D6RA61 4 9267619-9269570 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 USP17L24 ENSG00000232264 "Ubiquitin specific peptidase 17-like family member 24" Q0WX57 4 9325165-9327116 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L25 ENSG00000230430 "Ubiquitin specific peptidase 17-like family member 25" Q0WX57 4 9329911-9331862 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L26 ENSG00000229579 "Ubiquitin specific peptidase 17-like family member 26" Q0WX57 4 9334658-9336609 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L27 ENSG00000235780 "Ubiquitin specific peptidase 17-like family member 27" Q0WX57 4 9344148-9345740 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L28 ENSG00000231051 "Ubiquitin specific peptidase 17-like family member 28" Q0WX57 4 9348893-9350485 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L29 ENSG00000231637 "Ubiquitin specific peptidase 17-like family member 29" Q0WX57 4 9353638-9355230 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L3 "USP17B, USP17F" ENSG00000225327 "Ubiquitin specific peptidase 17-like family member 3" A6NCW0 8 7976393-7977985 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L30 ENSG00000228856 "Ubiquitin specific peptidase 17-like family member 30" Q0WX57 4 9363129-9364721 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L5 ENSG00000227140 "Ubiquitin specific peptidase 17-like family member 5" A8MUK1 4 9339403-9340995 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain "HPA045642: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP19 "KIAA0891, ZMYND9" ENSG00000172046 "Ubiquitin specific peptidase 19" O94966 3 49108046-49120938 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "unprognostic (3.23e-2)" "unprognostic (2.12e-1)" "unprognostic (5.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-2)" "unprognostic (3.90e-3)" "unprognostic (2.99e-2)" "unprognostic (3.00e-3)" "unprognostic (2.69e-1)" "unprognostic (3.65e-2)" "unprognostic (2.31e-2)" "unprognostic (1.26e-1)" "prognostic favourable (7.05e-9)" "unprognostic (2.99e-1)" "unprognostic (2.11e-1)" "unprognostic (1.72e-3)" "unprognostic (7.54e-2)" 13.9 19.5 10.3 14.6 12.2 16.2 14.9 19.4 37.1 17.0 16.3 12.5 19.6 14.6 18.7 17.9 14.3 17.2 19.9 17.9 10.3 9.4 14.8 16.5 14.7 13.8 11.9 9.5 17.2 15.2 22.4 13.2 17.6 11.4 14.2 10.9 14.9 24.7 26.0 57.3 18.4 16.1 13.9 8.5 17.5 15.1 14.9 11.7 23.0 17.7 15.2 12.6 17.4 14.1 5.1 6.7 12.3 5.7 4.3 8.4 5.3 8.1 11.8 14.1 19.9 17.4 11.9 18.0 9.2 12.3 17.2 13.1 11.8 12.5 17.6 9.4 11.5 10.9 17.8 13.4 7.2 13.8 13.8 17.1 23.6 10.8 18.0 19.4 18.1 16.9 10.4 16.2 11.8 11.3 13.4 13.3 8.6 10.6 18.4 20.1 26.7 17.3 8.9 10.4 20.4 10.6 15.6 7.8 22.2 13.6 17.9 16.0 12.1 25.8 8.9 11.5 14.0 17.0 13.9 33.7 32.6 15.6 14.8 15.4 14.3 12.3 4.9 7.5 7.2 5.3 6.8 4.6 5.8 8.4 6.7 5.1 5.7 6.2 8.8 4.3 5.7 3.0 4.1 5.3 10.3 12.2 19.4 37.1 10.3 9.4 11.9 9.5 11.4 11.7 USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381726 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 79.9" "Cell line enriched" "Detected in many" 4 "U-266/70: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "naive CD4 T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" Cytosol "Plasma membrane" "HPA006777: AB_1080507, HPA007222: AB_1080505" "unprognostic (6.83e-2)" "unprognostic (2.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-3)" "unprognostic (8.02e-3)" "unprognostic (7.33e-2)" "prognostic favourable (3.09e-11)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (2.66e-2)" 3.1 4.8 6.9 1.4 12.2 1.5 1.6 12.6 16.1 2.5 5.9 10.0 0.0 7.9 2.6 6.4 5.9 7.0 2.2 26.8 5.7 3.1 29.7 10.6 2.2 0.7 5.7 6.2 2.9 10.1 18.4 7.6 1.3 6.7 2.3 3.9 19.1 3.2 2.4 79.9 4.6 11.7 4.2 3.8 0.8 2.7 36.1 8.8 0.0 2.2 25.2 1.0 1.9 2.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 3.4 0.3 0.5 1.9 0.1 0.1 0.7 0.4 0.2 0.0 0.3 3.6 0.5 5.9 1.1 0.6 0.6 4.7 1.7 0.1 4.2 0.6 1.7 2.5 7.3 1.6 0.0 1.6 0.6 0.3 0.4 1.2 0.3 8.2 0.5 1.0 2.4 0.0 0.4 0.9 0.7 0.0 1.3 0.8 2.7 0.2 7.2 2.2 2.0 1.6 0.4 5.3 3.6 0.0 0.0 0.9 0.5 0.5 34.4 7.6 0.1 0.0 1.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.0 1.3 0.7 0.0 0.0 0.0 0.0 0.3 0.3 6.9 12.2 12.6 16.1 5.7 3.1 5.7 6.2 6.7 8.8 USP20 KIAA1003 ENSG00000136878 "Ubiquitin specific peptidase 20" Q9Y2K6 9 129834698-129881838 "Enzymes, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 30.4;MOLT-4: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006287, HPA007008" Uncertain Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Nucleoplasm, Plasma membrane, Cytosol" "HPA006287: AB_1080510, HPA007008: " "unprognostic (2.64e-2)" "prognostic favourable (8.01e-4)" "prognostic unfavourable (2.48e-4)" "prognostic favourable (4.01e-4)" "unprognostic (4.69e-1)" "unprognostic (1.89e-2)" "unprognostic (2.25e-1)" "unprognostic (2.55e-3)" "unprognostic (1.24e-1)" "unprognostic (7.89e-2)" "prognostic favourable (1.54e-7)" "unprognostic (2.09e-1)" "prognostic favourable (5.65e-5)" "unprognostic (1.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-2)" "unprognostic (1.24e-2)" 7.8 13.2 10.5 15.2 14.6 24.4 8.5 23.0 19.6 13.2 12.1 12.7 10.2 9.7 13.3 6.2 9.3 11.6 12.5 8.8 10.5 13.7 8.0 7.3 9.1 19.6 9.6 16.1 16.8 12.9 11.5 19.0 8.0 11.9 14.9 6.1 10.8 13.7 17.2 10.2 14.0 11.8 20.0 8.8 14.6 10.2 14.0 8.8 51.5 19.3 4.2 15.3 15.6 10.0 3.8 2.4 4.8 1.7 9.0 10.7 5.4 3.0 2.9 5.2 7.0 6.8 5.8 7.4 4.9 4.1 3.7 2.6 2.4 3.3 4.1 4.2 4.7 7.6 3.1 3.5 1.5 22.2 4.1 7.6 8.0 1.6 4.8 7.1 5.7 5.1 5.1 4.9 3.7 4.0 30.4 5.1 2.2 8.0 27.8 16.9 4.1 7.0 4.7 5.8 7.0 2.9 3.3 1.1 5.8 5.7 7.2 4.6 7.5 10.0 5.9 4.1 1.9 5.5 3.2 5.1 7.4 2.9 8.2 9.4 3.8 1.0 1.7 4.8 8.6 1.4 9.3 3.7 8.8 8.3 2.4 3.8 10.4 8.9 2.8 9.0 1.3 2.1 10.7 5.4 10.5 14.6 23.0 19.6 10.5 13.7 9.6 16.1 11.9 8.8 USP21 "USP16, USP23" ENSG00000143258 "Ubiquitin specific peptidase 21" Q9UK80 1 161159450-161165723 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028397 Uncertain Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" Cytosol "Nucleoplasm, Plasma membrane" "HPA028397: AB_10603227" "unprognostic (9.17e-2)" "unprognostic (1.44e-1)" "unprognostic (3.95e-2)" "prognostic unfavourable (7.05e-4)" "unprognostic (1.22e-2)" "unprognostic (1.26e-2)" "prognostic unfavourable (1.68e-4)" "unprognostic (5.35e-2)" "unprognostic (6.73e-2)" "unprognostic (2.76e-2)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "prognostic unfavourable (9.50e-6)" "unprognostic (2.45e-1)" "unprognostic (3.28e-1)" "unprognostic (2.13e-2)" "prognostic favourable (3.35e-5)" 11.8 16.4 22.1 12.8 21.2 15.3 19.1 23.6 24.8 18.1 16.1 25.5 14.0 15.5 19.7 14.6 18.3 33.3 14.1 13.7 20.9 12.1 15.4 10.6 14.0 16.7 26.4 14.1 28.3 19.0 24.4 17.2 15.2 20.5 18.1 13.1 17.1 19.0 25.3 19.4 23.5 15.4 15.1 17.0 18.7 16.0 17.0 22.9 16.0 24.5 9.6 15.6 17.9 19.2 14.1 12.0 18.3 11.1 13.4 17.2 10.7 7.4 12.8 16.9 16.3 13.5 11.3 10.4 5.5 9.0 15.2 11.9 11.8 14.7 9.7 9.5 6.8 12.9 10.9 10.7 8.4 18.5 18.3 11.6 18.5 9.2 9.7 10.3 8.7 9.5 14.4 10.4 15.0 10.7 17.1 13.6 9.6 13.7 18.2 16.2 15.8 16.3 17.3 5.6 16.3 8.9 8.9 15.4 19.8 10.3 10.8 8.3 23.8 16.6 6.2 10.9 9.7 7.6 9.4 27.5 21.3 14.4 10.0 8.9 9.8 13.0 11.1 18.3 14.9 7.1 17.2 12.8 13.8 15.4 12.0 14.1 16.0 14.6 9.6 13.4 7.7 12.0 13.3 10.7 22.1 21.2 23.6 24.8 20.9 12.1 26.4 14.1 20.5 22.9 USP22 "KIAA1063, USP3L" ENSG00000124422 "Ubiquitin specific peptidase 22" Q9UPT9 17 20999593-21043760 "Enzymes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044980 Supported Approved "Nuclear speckles" "Nuclear speckles" "HPA044980: AB_10794503" "unprognostic (7.24e-2)" "unprognostic (5.38e-2)" "unprognostic (7.67e-2)" "unprognostic (6.19e-2)" "unprognostic (4.72e-1)" "unprognostic (1.11e-2)" "prognostic unfavourable (9.66e-4)" "unprognostic (2.17e-2)" "unprognostic (7.81e-2)" "unprognostic (6.37e-2)" "unprognostic (1.07e-3)" "unprognostic (5.68e-2)" "prognostic favourable (1.53e-7)" "unprognostic (8.95e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (1.79e-2)" 22.5 33.0 40.7 21.5 49.5 25.9 24.6 66.1 66.4 26.8 23.6 31.9 25.1 18.9 36.7 29.3 21.9 33.9 23.0 44.1 38.7 47.6 27.7 22.9 26.1 25.1 31.0 40.7 45.6 24.5 47.4 32.2 22.4 35.1 27.5 20.5 28.7 20.0 29.5 47.6 22.1 21.1 31.2 24.8 23.7 22.7 20.2 23.7 41.2 32.8 24.8 27.3 25.1 23.2 13.7 12.1 13.4 13.3 8.9 15.5 6.9 21.6 39.4 38.3 32.9 22.4 23.3 18.3 25.0 19.3 22.6 19.2 45.4 9.8 29.8 24.1 38.4 23.4 37.1 29.8 33.8 14.2 25.7 24.7 26.2 22.0 26.5 27.1 21.6 25.6 17.9 25.5 26.9 28.1 28.0 10.8 31.9 22.3 37.9 12.9 19.7 13.0 42.0 60.6 20.3 20.8 31.9 18.5 38.1 32.3 13.4 26.3 22.5 16.1 35.6 23.1 30.7 23.6 33.8 11.7 15.6 99.0 23.5 14.5 35.6 6.8 13.3 12.6 11.0 9.8 11.1 10.9 11.7 10.9 12.1 13.7 15.5 14.6 13.4 8.9 12.2 10.2 7.8 6.9 40.7 49.5 66.1 66.4 38.7 47.6 31.0 40.7 35.1 23.7 USP24 KIAA1057 ENSG00000162402 "Ubiquitin specific peptidase 24" Q9UPU5 1 55066359-55215113 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 46.0" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026723, HPA028428, HPA067124" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA026723: AB_10599851, HPA028428: AB_10600991, HPA067124: " "unprognostic (2.28e-1)" "unprognostic (9.81e-3)" "unprognostic (4.70e-3)" "unprognostic (4.86e-3)" "unprognostic (9.31e-3)" "unprognostic (4.84e-3)" "prognostic unfavourable (1.34e-7)" "unprognostic (2.04e-1)" "unprognostic (6.93e-2)" "unprognostic (2.98e-1)" "unprognostic (5.08e-2)" "unprognostic (1.86e-1)" "unprognostic (8.12e-2)" "unprognostic (1.79e-1)" "unprognostic (6.42e-2)" "unprognostic (4.12e-2)" "unprognostic (1.64e-1)" 12.3 7.6 7.5 12.1 8.8 30.1 10.6 20.1 8.5 7.8 10.2 6.8 10.6 5.0 10.1 7.0 7.7 6.9 7.0 14.7 7.9 6.4 10.4 9.3 7.6 12.7 8.0 5.6 10.9 7.3 15.5 16.9 5.8 6.9 7.6 8.5 5.1 9.7 10.7 46.0 8.9 8.7 7.3 6.2 10.9 7.8 4.9 8.7 16.4 7.4 11.5 12.7 9.7 13.7 6.0 10.5 5.9 2.2 3.8 4.5 1.1 17.8 9.8 12.3 6.7 16.1 14.1 14.2 7.9 10.0 11.4 11.9 14.0 6.3 14.3 8.8 14.6 14.5 16.3 13.3 17.9 15.0 9.9 28.7 21.5 16.3 9.6 19.7 22.3 12.3 11.9 17.3 19.7 10.3 26.4 6.0 15.2 4.2 11.9 10.5 18.1 11.9 12.3 15.7 6.2 19.8 12.1 10.9 7.6 13.5 9.7 11.8 6.7 9.8 13.9 10.4 10.1 12.5 12.6 7.6 5.7 18.8 9.9 16.5 9.3 5.9 2.0 2.5 4.5 1.8 2.8 4.8 3.5 3.5 1.8 6.0 3.2 4.2 2.3 3.8 2.2 10.5 1.9 1.1 7.5 8.8 20.1 8.5 7.9 6.4 8.0 5.6 6.9 8.7 USP25 USP21 ENSG00000155313 "Ubiquitin specific peptidase 25" Q9UHP3 21 15730025-15880069 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018297, HPA024142" Approved Supported Cytosol Cytosol "HPA018297: AB_1858672, HPA024142: AB_1858673" "unprognostic (6.35e-2)" "unprognostic (1.50e-1)" "unprognostic (6.90e-2)" "unprognostic (6.29e-2)" "unprognostic (1.39e-1)" "unprognostic (2.88e-2)" "unprognostic (3.91e-2)" "unprognostic (1.65e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (2.33e-2)" "unprognostic (1.40e-1)" "unprognostic (8.24e-3)" "unprognostic (2.34e-3)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.32e-2)" 14.9 8.5 11.0 14.2 15.5 12.4 28.7 11.3 11.1 17.5 11.8 6.6 17.8 6.5 20.7 14.5 12.6 10.6 10.1 17.8 9.9 5.8 12.9 10.4 22.1 14.8 7.6 7.1 14.5 8.2 8.1 8.4 17.7 7.7 12.9 8.6 7.8 11.4 13.6 56.3 8.3 12.3 19.2 7.3 11.6 9.0 26.1 7.5 16.5 10.5 14.6 9.6 13.8 18.1 3.1 2.8 5.8 2.9 2.3 7.2 1.6 13.0 9.9 9.4 1.4 17.3 25.9 11.0 9.4 9.4 7.0 8.9 8.6 7.5 14.1 13.9 14.8 7.0 7.2 12.4 9.7 14.0 8.2 11.5 10.5 6.6 28.8 15.2 5.3 16.8 15.2 11.3 32.7 24.5 14.8 26.6 12.6 5.4 17.3 2.9 11.5 8.8 13.2 8.7 10.7 19.0 3.5 2.0 5.6 13.4 11.4 8.7 6.1 8.9 23.3 10.9 7.1 11.4 5.2 7.8 4.7 11.2 7.1 6.8 8.0 0.0 2.9 3.6 4.0 2.8 4.4 3.1 3.4 7.2 2.5 2.2 3.2 4.8 5.8 2.3 2.5 2.8 4.4 1.6 11.0 15.5 11.3 11.1 9.9 5.8 7.6 7.1 7.7 7.5 USP26 ENSG00000134588 "Ubiquitin specific peptidase 26" Q9BXU7 X 133024631-133097109 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 3.8" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "unprognostic (7.92e-4)" "unprognostic (3.59e-2)" "unprognostic (1.99e-2)" "unprognostic (2.08e-1)" 0.1 0.1 0.1 0.1 0.1 0.3 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 0.1 0.1 0.1 0.1 0.1 3.8 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.5 0.1 0.2 0.3 0.0 0.0 0.5 0.4 0.5 0.4 0.1 0.1 0.2 0.2 0.7 0.1 0.2 0.1 0.7 0.1 0.1 0.1 0.7 0.1 0.2 0.3 1.0 0.3 1.0 0.3 0.1 0.1 0.0 1.5 0.6 0.4 0.1 0.1 0.4 0.4 0.2 0.2 0.1 0.7 0.4 0.3 0.4 0.1 0.0 0.9 0.5 0.5 0.2 0.1 0.1 0.2 0.1 0.7 0.3 0.9 0.1 0.3 0.4 0.9 0.3 0.1 0.2 0.4 0.3 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 USP27X USP27 ENSG00000273820 "Ubiquitin specific peptidase 27, X-linked" A6NNY8 X 49879948-49882565 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077264 Approved Nucleoplasm,Vesicles Vesicles Nucleoplasm "HPA077264: " "unprognostic (4.12e-2)" "unprognostic (9.58e-3)" "unprognostic (2.29e-1)" "unprognostic (4.66e-2)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "prognostic unfavourable (6.14e-4)" "unprognostic (3.10e-3)" "unprognostic (3.91e-2)" "unprognostic (1.31e-2)" "prognostic favourable (9.31e-4)" "unprognostic (5.37e-2)" "unprognostic (7.45e-3)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.58e-1)" 1.8 3.3 1.8 5.9 2.9 0.3 7.7 1.7 7.4 3.9 5.9 4.8 2.2 1.1 12.7 4.1 3.1 4.7 3.8 3.9 2.2 3.5 3.5 6.1 1.9 1.3 3.2 8.8 3.2 4.1 0.8 15.5 2.8 4.1 1.7 4.1 5.2 3.9 7.5 2.6 4.7 3.9 1.3 2.0 1.9 3.8 1.9 2.8 3.2 3.6 2.2 3.7 3.1 1.7 1.0 0.7 0.7 0.3 1.3 0.4 2.1 5.6 6.5 7.5 6.2 5.0 5.4 2.4 4.1 2.8 2.3 10.0 2.5 1.4 2.3 6.4 3.6 9.3 6.2 4.1 2.9 4.3 2.3 1.6 9.2 4.2 0.7 5.1 7.0 4.2 4.0 4.0 3.9 4.6 2.4 4.5 5.3 3.5 2.0 7.0 3.9 3.7 5.6 0.5 4.6 2.1 1.7 4.9 4.8 4.5 5.8 5.2 1.7 2.9 3.3 6.4 5.7 0.9 2.2 0.5 1.0 3.8 2.0 3.6 0.7 0.4 0.1 0.6 0.4 0.8 0.6 0.5 0.3 1.0 1.7 0.8 0.6 0.7 0.3 0.7 0.4 1.3 0.4 USP28 KIAA1515 ENSG00000048028 "Ubiquitin specific peptidase 28" Q96RU2 11 113797874-113875570 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 40.1;skeletal muscle: 50.2" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006778, HPA006779" Enhanced Supported "Nucleoplasm,Nuclear bodies" Nucleoplasm "Nuclear bodies" "HPA006778: AB_1080520, HPA006779: AB_1080517" "unprognostic (2.54e-1)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" "unprognostic (3.72e-2)" "unprognostic (5.51e-2)" "unprognostic (2.30e-1)" "unprognostic (9.73e-3)" "unprognostic (3.00e-1)" "unprognostic (2.04e-3)" "unprognostic (1.82e-3)" "unprognostic (3.17e-2)" "unprognostic (1.19e-1)" "unprognostic (5.11e-2)" "unprognostic (2.06e-2)" "unprognostic (9.03e-2)" "unprognostic (1.35e-3)" "unprognostic (5.03e-2)" 3.9 3.4 4.8 8.6 5.7 2.4 5.7 26.4 8.6 11.6 5.1 4.9 14.0 4.7 6.0 6.0 5.7 5.0 4.0 40.1 5.0 4.8 5.1 5.6 5.1 7.2 6.8 4.5 7.5 4.1 10.6 9.7 3.9 4.8 8.9 6.0 5.7 5.7 12.2 50.2 3.5 5.1 11.6 6.4 6.9 4.4 5.5 3.8 3.6 5.1 10.1 7.7 7.1 4.6 10.3 4.1 2.1 3.7 17.9 16.2 6.0 10.3 11.6 15.7 20.7 12.8 12.7 11.1 7.6 10.5 10.3 17.7 17.1 14.9 13.7 17.4 10.3 20.3 22.1 14.3 14.4 15.3 10.0 7.3 8.1 9.2 7.9 9.4 7.3 7.6 10.9 11.9 14.2 18.6 12.6 8.9 10.8 5.2 7.1 15.3 18.8 8.4 17.6 21.8 16.6 11.4 10.2 6.9 7.4 18.1 6.2 5.9 15.1 3.3 9.8 11.5 17.2 10.4 7.8 6.1 8.7 11.6 1.1 18.3 7.4 0.1 3.2 2.1 16.2 2.4 8.4 10.3 4.1 11.4 4.1 8.4 2.7 9.4 0.9 17.9 3.7 1.2 5.6 6.0 4.8 5.7 26.4 8.6 5.0 4.8 6.8 4.5 4.8 3.8 USP29 ENSG00000131864 "Ubiquitin specific peptidase 29" Q9HBJ7 19 57119138-57131926 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "blood: 4.1;bone marrow: 2.7;pancreas: 2.1;skin 1: 2.3;testis: 8.4" "Cell line enhanced" "Detected in some" "BEWO: 3.3;HEK 293: 3.2" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" HPA076515 Enhanced "HPA076515: " "unprognostic (1.32e-1)" 0.1 0.1 0.2 0.0 0.2 2.7 0.1 0.1 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.3 0.2 0.1 0.1 0.1 0.3 0.1 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.7 0.0 0.2 2.3 0.1 0.0 0.1 0.1 0.4 8.4 0.4 0.0 0.7 0.1 1.1 1.9 4.1 1.1 1.2 0.8 0.6 0.1 0.7 0.8 0.3 0.0 0.0 3.3 0.0 0.0 0.1 0.1 1.7 0.0 0.9 0.0 0.0 2.0 0.0 0.0 0.0 1.0 3.2 0.8 0.0 0.0 1.1 0.0 1.9 0.9 1.0 1.4 0.0 0.0 0.3 0.9 0.0 0.7 0.0 1.2 0.0 1.0 0.9 0.0 1.0 0.0 2.1 2.0 0.7 0.6 0.4 0.2 0.8 1.3 1.5 1.2 0.5 0.0 0.0 1.6 0.5 1.5 0.5 0.8 0.0 3.1 1.1 1.1 0.8 0.7 0.6 0.5 0.7 0.3 0.3 1.1 0.7 0.7 4.1 1.2 0.4 1.9 0.5 0.6 USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 33.4" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053275, HPA060513, HPA077975" Supported Nucleoplasm "Intracellular and membrane" Nucleoplasm "HPA053275: , HPA060513: , HPA077975: " "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (7.88e-2)" "unprognostic (3.33e-2)" "unprognostic (2.16e-2)" "unprognostic (6.03e-2)" "unprognostic (6.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.62e-2)" "unprognostic (2.36e-1)" "unprognostic (3.54e-2)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.61e-2)" "unprognostic (2.78e-1)" "unprognostic (6.21e-2)" "prognostic favourable (1.38e-4)" 16.0 9.0 5.9 20.4 6.5 38.6 21.3 33.4 6.6 12.7 19.1 6.0 16.8 16.2 18.1 13.3 13.6 10.4 14.2 7.6 6.6 4.4 12.9 10.8 17.5 28.2 8.1 3.9 19.5 27.1 7.1 8.2 10.2 7.9 12.4 11.5 8.2 18.5 14.8 12.4 15.9 19.0 16.1 8.0 23.6 14.7 10.3 7.8 22.7 12.5 11.4 22.5 21.3 17.9 11.4 20.6 52.6 28.1 7.2 12.9 13.4 9.2 30.1 15.6 9.7 7.7 12.6 13.7 7.9 9.9 7.7 9.4 11.8 17.3 9.3 12.6 7.8 11.7 14.5 12.3 7.5 15.3 7.8 10.6 10.7 12.7 6.5 6.2 12.8 9.0 16.2 9.3 16.2 16.6 14.0 11.9 4.9 14.3 13.0 10.2 19.7 13.0 19.1 9.4 16.5 9.2 31.6 13.7 10.6 4.9 16.1 9.7 9.7 12.2 15.8 8.9 18.5 5.2 10.5 10.8 19.9 20.8 8.5 17.4 7.3 28.8 28.1 3.5 8.4 22.6 9.3 10.3 11.9 8.6 20.6 11.4 12.9 9.3 52.6 7.2 18.7 4.1 9.1 13.4 5.9 6.5 33.4 6.6 6.6 4.4 8.1 3.9 7.9 7.8 USP30 "FLJ40511, MGC10702" ENSG00000135093 "Ubiquitin specific peptidase 30" Q70CQ3 12 109023089-109088026 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016952 Approved "HPA016952: AB_1858680" "unprognostic (2.34e-1)" "unprognostic (1.57e-2)" "unprognostic (7.04e-2)" "unprognostic (9.91e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (1.91e-1)" "unprognostic (3.60e-3)" "unprognostic (1.98e-1)" "unprognostic (4.96e-2)" "unprognostic (5.07e-2)" "unprognostic (1.07e-1)" "prognostic favourable (5.23e-6)" "unprognostic (2.49e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-3)" 11.7 18.9 12.7 9.0 17.6 12.2 10.4 11.9 21.0 10.3 13.2 29.2 13.6 14.9 12.4 8.5 9.2 11.1 8.4 9.0 10.3 10.6 12.4 21.7 8.9 10.4 16.6 7.8 17.5 12.4 14.7 13.0 6.7 16.0 9.4 11.3 16.4 10.1 12.4 16.4 13.6 14.1 8.6 14.3 9.8 8.5 21.3 16.3 8.7 11.1 5.3 7.1 10.8 8.1 14.2 12.2 12.7 11.0 18.3 17.4 6.0 4.7 3.6 9.7 8.3 6.8 7.8 5.4 5.3 6.9 6.2 5.5 4.3 3.6 11.9 4.5 5.2 5.3 8.4 5.5 7.1 13.8 10.6 3.8 3.3 6.1 7.3 7.6 4.3 9.4 6.7 5.5 5.4 7.1 5.7 5.8 5.2 5.5 11.9 4.3 3.0 10.2 12.9 6.9 7.2 5.0 5.7 8.8 7.9 7.2 5.4 5.6 13.4 5.9 5.1 5.7 3.1 5.5 3.5 14.6 12.1 17.9 6.1 4.6 6.3 9.5 7.1 12.7 15.4 11.0 17.4 14.2 12.9 14.3 4.6 14.2 13.7 12.6 4.2 18.3 8.8 12.2 11.2 6.0 12.7 17.6 11.9 21.0 10.3 10.6 16.6 7.8 16.0 16.3 USP31 KIAA1203 ENSG00000103404 "Ubiquitin specific peptidase 31" Q70CQ4 16 23061406-23149270 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006937 Uncertain Approved Cytosol Cytosol "HPA006937: AB_1080523" "unprognostic (6.45e-2)" "unprognostic (2.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.52e-1)" "unprognostic (6.15e-2)" "unprognostic (2.01e-1)" "prognostic unfavourable (4.41e-5)" "unprognostic (5.59e-2)" "unprognostic (3.75e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-3)" 6.3 5.3 11.2 4.0 16.6 7.1 8.7 12.7 16.5 10.9 4.9 19.7 2.6 3.7 15.3 7.7 9.3 6.5 4.1 11.0 9.0 6.3 6.2 7.7 7.3 3.6 24.6 8.1 3.7 6.3 20.6 10.4 7.4 17.4 9.6 4.9 2.8 6.0 8.5 10.9 15.9 3.4 14.2 14.8 2.8 3.5 20.7 19.3 1.7 4.2 2.4 4.9 13.4 9.5 0.5 0.8 0.6 1.3 0.1 2.1 0.2 9.4 10.0 2.9 4.0 5.3 4.1 2.7 3.3 3.0 4.3 5.1 6.3 5.8 3.2 3.5 4.1 12.5 7.1 12.9 7.1 2.3 2.9 1.3 5.8 13.2 6.6 3.3 3.6 3.5 11.2 7.9 18.3 7.6 3.8 9.9 5.8 6.5 1.6 2.7 5.7 3.1 7.9 8.1 6.3 6.4 14.2 7.7 5.0 5.1 10.2 2.9 4.1 7.3 4.4 8.7 6.4 4.4 8.9 3.3 5.4 3.4 6.2 4.4 3.4 0.1 0.7 0.6 0.8 0.3 2.1 0.1 0.7 1.5 0.8 0.5 0.8 0.8 0.1 0.1 1.3 0.2 1.3 0.2 11.2 16.6 12.7 16.5 9.0 6.3 24.6 8.1 17.4 19.3 USP32 "NY-REN-60, USP10" ENSG00000170832 "Ubiquitin specific peptidase 32" Q8NFA0 17 60179094-60422470 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 58.4" "Cell line enhanced" "Detected in all" "MCF7: 60.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 28.4" "Group enriched" "Detected in many" 10 "dendritic cells: 28.4;granulocytes: 13.5" HPA044365 Approved Approved "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA044365: " "unprognostic (4.10e-2)" "unprognostic (3.38e-2)" "unprognostic (3.57e-2)" "prognostic unfavourable (1.50e-4)" "unprognostic (2.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.90e-3)" "unprognostic (2.33e-2)" "unprognostic (2.24e-1)" "unprognostic (3.93e-1)" "unprognostic (6.49e-2)" "unprognostic (2.78e-1)" "unprognostic (2.82e-1)" "unprognostic (1.97e-1)" "unprognostic (7.23e-2)" "unprognostic (8.35e-2)" "unprognostic (4.16e-2)" 9.5 13.9 17.3 10.8 19.5 20.6 10.9 14.6 20.3 8.0 8.5 18.9 7.9 7.2 8.2 5.4 13.1 7.4 9.1 11.1 14.7 12.2 15.5 19.7 12.5 8.6 18.8 14.3 7.4 8.5 17.3 11.4 9.8 19.2 8.7 8.9 11.6 8.2 9.0 23.0 12.2 7.2 9.8 16.5 12.1 8.1 58.4 18.1 7.3 15.6 7.9 8.5 8.8 8.5 1.4 28.4 13.5 2.1 0.6 1.1 0.9 10.9 12.5 6.6 10.6 16.8 15.8 6.3 9.0 13.5 11.7 15.1 6.5 7.1 6.8 7.5 16.5 5.8 11.3 12.4 20.7 5.1 5.0 13.5 9.9 7.1 16.8 10.7 12.4 14.8 9.1 15.8 14.6 12.8 13.7 5.6 14.5 60.4 10.8 7.6 7.8 6.0 5.2 17.6 4.1 12.3 8.0 4.7 7.0 7.4 2.2 11.5 9.2 14.9 10.8 17.9 18.7 11.2 8.3 5.8 11.0 6.3 8.9 8.4 11.6 4.3 2.1 7.2 1.0 1.8 0.7 1.4 0.7 0.8 4.1 1.1 0.5 1.0 13.5 0.6 2.0 28.4 1.1 0.9 17.3 19.5 14.6 20.3 14.7 12.2 18.8 14.3 19.2 18.1 USP33 "KIAA1097, VDU1" ENSG00000077254 "Ubiquitin specific peptidase 33" Q8TEY7 1 77695987-77759852 "Enzymes, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005719 Uncertain Supported "Nucleoplasm,Golgi apparatus" "Nucleoplasm, Golgi apparatus" "HPA005719: AB_10601708" "unprognostic (2.31e-3)" "unprognostic (2.73e-2)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (9.19e-3)" "unprognostic (1.88e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-1)" "unprognostic (2.67e-1)" "unprognostic (3.59e-1)" "unprognostic (5.36e-3)" "unprognostic (4.89e-2)" "unprognostic (5.76e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-2)" 30.8 27.1 28.1 18.8 32.1 24.6 28.6 55.3 37.5 21.6 20.4 20.6 18.5 20.2 23.3 23.0 17.8 19.2 21.7 17.0 30.7 30.6 26.0 20.3 21.0 20.7 26.0 25.4 25.3 17.0 28.8 23.4 34.6 38.7 24.6 21.0 21.4 19.5 19.8 16.3 19.4 23.8 19.8 21.4 22.3 19.5 19.9 21.6 27.8 25.1 12.9 20.3 21.0 20.0 15.7 12.2 33.2 18.4 12.3 17.8 10.6 16.3 7.5 25.9 17.9 37.3 32.6 22.3 17.9 17.1 21.9 24.6 9.9 14.1 12.2 17.0 17.4 12.9 18.8 12.3 26.8 11.2 14.7 43.1 18.3 8.6 23.2 14.7 10.9 24.0 9.7 21.1 15.5 19.4 16.8 10.7 16.4 6.3 13.2 14.7 25.0 14.8 12.8 27.3 8.6 20.6 16.8 21.8 16.8 12.5 16.7 25.0 9.3 16.0 16.2 20.2 14.4 20.3 16.9 8.7 11.1 11.9 15.3 17.4 10.2 33.2 15.4 20.0 15.1 15.0 15.3 13.4 14.7 15.2 11.5 15.7 17.8 15.6 20.9 12.3 18.4 12.2 13.2 10.6 28.1 32.1 55.3 37.5 30.7 30.6 26.0 25.4 38.7 21.6 USP34 "KIAA0570, KIAA0729" ENSG00000115464 "Ubiquitin specific peptidase 34" Q70CQ2 2 61187463-61470769 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025815, HPA070764" Uncertain Approved Nucleoplasm Nucleoplasm "HPA025815: AB_1858681, HPA070764: " "unprognostic (4.04e-2)" "unprognostic (8.21e-3)" "unprognostic (5.08e-2)" "unprognostic (3.14e-2)" "unprognostic (4.13e-2)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (8.91e-2)" "unprognostic (4.62e-2)" "unprognostic (9.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (6.34e-2)" "unprognostic (7.01e-2)" 17.2 19.6 31.8 37.2 25.6 24.8 28.3 77.1 35.5 22.5 22.7 14.4 31.1 11.4 22.2 44.5 18.6 17.5 20.0 16.9 30.5 24.0 20.5 21.5 29.7 34.2 22.0 21.2 24.7 17.2 33.5 40.3 13.4 22.0 22.7 21.5 21.2 16.9 45.2 27.0 31.6 21.0 22.7 20.8 24.8 19.3 26.4 25.3 21.7 23.2 13.9 33.5 19.1 16.7 6.0 5.8 3.4 4.6 5.2 7.5 2.3 16.6 11.9 15.5 16.0 29.5 19.8 13.0 10.3 14.5 9.2 8.8 16.7 6.4 39.5 10.9 22.1 9.1 12.2 13.5 17.2 14.1 9.6 23.9 11.6 26.8 24.8 17.7 15.2 21.6 17.5 16.7 25.1 19.3 16.3 12.8 20.4 15.6 11.6 25.8 10.5 9.4 12.5 18.9 10.5 27.1 20.4 12.8 13.7 16.2 12.0 17.7 6.3 12.9 17.2 14.6 19.4 8.6 13.4 14.9 7.3 41.5 13.7 16.5 12.5 3.4 2.0 2.8 7.5 2.2 6.7 5.1 5.1 5.5 1.8 6.0 5.8 7.5 3.4 5.2 4.6 5.8 4.5 2.3 31.8 25.6 77.1 35.5 30.5 24.0 22.0 21.2 22.0 25.3 USP35 KIAA1372 ENSG00000118369 "Ubiquitin specific peptidase 35" Q9P2H5 11 78188812-78214711 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 32.4" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "eosinophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055213, HPA058592" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" "Nucleoli fibrillar center" Nucleoplasm "HPA055213: , HPA058592: " "unprognostic (6.69e-2)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (6.87e-3)" "unprognostic (3.38e-2)" "unprognostic (1.08e-2)" "unprognostic (2.00e-1)" "unprognostic (1.46e-1)" "unprognostic (3.57e-2)" "unprognostic (3.84e-3)" "unprognostic (1.03e-2)" "unprognostic (3.11e-2)" "unprognostic (1.29e-3)" "unprognostic (2.93e-1)" "unprognostic (1.31e-1)" "unprognostic (4.38e-2)" "unprognostic (1.49e-2)" 4.9 17.1 5.1 5.4 9.3 3.8 5.2 10.4 15.0 6.4 5.8 8.0 6.3 5.5 6.8 5.4 5.6 5.4 5.6 8.7 6.1 6.7 5.0 13.8 5.6 4.8 6.7 8.8 6.6 6.4 32.4 12.0 7.1 15.0 5.0 3.4 7.7 4.0 5.6 5.6 3.2 5.3 7.8 4.5 4.6 3.9 5.3 4.0 1.9 7.7 2.9 4.1 5.2 6.6 0.0 0.1 3.4 0.6 0.1 0.3 0.2 2.1 3.3 5.7 6.0 9.8 9.0 3.9 4.9 5.8 5.8 4.1 8.3 4.6 1.7 5.1 9.2 5.7 3.8 7.6 3.4 12.2 2.0 2.8 8.6 4.8 7.6 1.8 8.3 7.6 5.1 12.1 3.5 7.1 3.9 4.2 4.5 1.9 4.6 7.2 1.7 5.3 2.8 5.3 2.1 4.6 3.9 2.8 5.4 3.8 5.0 1.8 4.2 1.5 8.6 10.7 6.1 12.6 2.6 5.7 1.9 2.6 3.2 1.9 6.2 0.0 0.2 3.4 0.1 0.6 0.0 0.0 0.2 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.1 0.1 0.1 0.2 5.1 9.3 10.4 15.0 6.1 6.7 6.7 8.8 15.0 4.0 USP36 "FLJ12851, KIAA1453" ENSG00000055483 "Ubiquitin specific peptidase 36" Q9P275 17 78787381-78841441 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012082, HPA012395, HPA052860" Uncertain Supported Enhanced "Nucleoli,Nuclear speckles" Nucleoli "Nuclear speckles" "HPA012082: AB_1858682, HPA012395: , HPA052860: " "unprognostic (1.94e-2)" "unprognostic (2.80e-2)" "unprognostic (1.07e-1)" "prognostic unfavourable (5.18e-5)" "unprognostic (9.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.50e-3)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" 26.3 23.4 12.9 21.3 16.0 36.5 28.1 28.3 17.4 17.2 16.4 25.4 19.2 12.3 25.1 22.2 14.6 18.0 21.9 17.4 10.4 11.2 15.9 16.4 20.0 17.2 17.5 16.0 41.3 33.6 19.6 30.0 23.4 14.6 21.0 15.1 20.4 21.8 45.5 19.5 29.3 15.1 25.2 14.5 18.2 17.3 20.8 13.7 12.8 19.3 11.2 22.2 24.6 18.1 6.7 12.4 8.9 5.3 5.6 8.8 2.5 15.7 19.1 5.6 10.4 12.1 13.5 10.8 13.0 13.2 12.5 8.4 18.5 8.0 20.2 6.6 11.5 11.6 13.2 9.6 22.4 4.8 20.0 18.4 27.8 19.2 12.4 20.1 10.1 11.7 16.0 17.8 39.9 10.8 14.6 21.3 10.3 12.1 18.3 20.4 8.7 15.3 14.1 12.3 13.5 7.9 16.6 16.6 10.1 9.3 43.5 23.6 11.2 12.8 9.2 29.5 13.7 17.1 22.9 15.8 6.2 24.8 11.6 15.8 9.2 8.9 3.9 3.1 7.6 5.3 8.8 6.4 7.2 6.4 2.3 6.7 8.0 7.7 5.7 5.6 3.3 12.4 4.8 2.5 12.9 16.0 28.3 17.4 10.4 11.2 17.5 16.0 14.6 13.7 USP37 KIAA1594 ENSG00000135913 "Ubiquitin specific peptidase 37" Q86T82 2 218450251-218568361 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045160 Approved Approved Nucleoplasm,Nucleoli "Nucleoplasm, Nucleoli" "HPA045160: AB_10795620" "unprognostic (7.00e-2)" "unprognostic (2.29e-1)" "unprognostic (8.83e-2)" "unprognostic (9.19e-4)" "unprognostic (1.83e-1)" "prognostic favourable (2.85e-4)" "unprognostic (2.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.66e-3)" "unprognostic (1.17e-1)" "unprognostic (3.78e-3)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.87e-1)" "unprognostic (6.69e-2)" "unprognostic (6.41e-3)" 10.4 8.4 9.2 9.7 10.5 19.2 9.0 16.2 10.0 8.3 6.6 10.4 8.0 5.8 9.6 15.8 8.2 7.8 7.0 6.9 7.4 5.5 6.1 7.4 8.1 10.5 8.7 7.8 15.3 6.9 10.7 17.1 8.5 8.7 7.3 7.0 7.4 9.7 9.6 11.1 9.9 7.2 8.1 10.2 7.0 6.6 22.2 10.5 13.4 9.8 5.4 9.4 10.5 9.1 7.4 6.1 7.4 4.8 5.9 9.0 2.5 7.3 5.4 11.4 8.8 3.0 3.7 9.7 5.6 4.1 9.9 11.1 10.2 5.9 6.7 6.2 4.4 7.1 12.5 6.3 10.9 9.2 6.6 18.2 10.9 6.7 3.4 11.8 9.1 2.0 3.8 10.3 7.5 4.2 13.1 13.0 6.2 5.5 15.2 8.1 9.8 4.7 12.3 17.1 6.2 3.4 8.8 12.5 6.8 9.0 4.5 5.7 5.2 8.4 5.3 11.1 9.8 6.2 7.4 8.9 7.8 13.8 6.0 8.8 7.5 6.5 4.2 7.4 7.0 4.8 7.3 5.4 5.8 5.9 4.4 7.4 9.0 5.7 3.5 5.9 4.4 6.1 7.3 2.5 9.2 10.5 16.2 10.0 7.4 5.5 8.7 7.8 8.7 10.5 USP38 "HP43.8KD, KIAA1891" ENSG00000170185 "Ubiquitin specific peptidase 38" Q8NB14 4 143184917-143223830 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 45.3" "Cell line enhanced" "Detected in all" "U-266/84: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036990, HPA047948" Uncertain Approved Nucleoplasm,Centrosome,Cytosol Nucleoplasm "Centrosome, Cytosol" "HPA036990: , HPA047948: AB_2680220" "unprognostic (5.01e-2)" "unprognostic (2.45e-1)" "unprognostic (2.04e-3)" "unprognostic (2.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.61e-2)" "unprognostic (1.67e-1)" "unprognostic (7.49e-2)" "unprognostic (3.66e-2)" "unprognostic (3.97e-2)" "unprognostic (8.03e-2)" "unprognostic (7.72e-3)" "prognostic favourable (1.20e-4)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" 7.7 7.8 6.6 6.6 6.5 19.1 8.3 7.4 7.8 7.9 12.1 8.6 8.8 8.8 8.3 7.1 8.6 7.1 7.6 12.5 6.6 5.3 9.3 15.2 12.7 11.1 10.3 5.1 6.3 8.8 10.0 6.2 11.4 5.9 6.6 6.6 7.1 7.2 7.0 45.3 8.9 13.2 6.5 10.8 10.6 7.4 7.5 8.2 22.6 8.6 10.2 8.4 7.8 8.8 6.3 8.1 12.5 5.7 12.3 9.9 5.0 4.7 4.5 4.0 6.8 5.2 5.2 2.9 7.6 7.4 7.0 6.0 12.9 7.0 5.9 5.4 6.4 3.8 9.3 7.5 5.8 14.4 6.0 5.4 5.3 2.7 7.2 10.9 5.4 6.3 6.9 7.2 5.8 7.0 11.7 18.5 4.7 7.5 14.2 2.0 3.6 8.7 9.4 5.9 5.6 4.5 5.5 8.1 7.3 5.9 10.3 6.6 6.3 4.1 8.3 6.5 5.3 5.6 7.9 20.7 35.1 10.7 6.6 8.4 5.4 12.5 5.4 11.7 7.5 5.7 9.6 6.3 6.6 6.5 8.1 5.7 6.7 5.7 5.4 12.3 5.7 3.5 9.9 5.0 6.6 6.5 7.4 7.7 6.6 5.3 10.3 5.1 5.9 8.2 USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277831-49340712 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018499 Approved Supported "Plasma membrane,Cytosol" "Plasma membrane, Cytosol" "HPA018499: AB_1858689" "unprognostic (2.34e-3)" "unprognostic (1.52e-1)" "unprognostic (2.22e-3)" "unprognostic (6.12e-2)" "unprognostic (3.51e-1)" "unprognostic (4.33e-2)" "unprognostic (9.42e-2)" "prognostic favourable (4.46e-5)" "unprognostic (3.54e-1)" "unprognostic (9.07e-3)" "unprognostic (2.78e-2)" "unprognostic (1.70e-3)" "prognostic favourable (4.29e-5)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 22.1 18.4 21.4 22.4 29.3 41.4 23.1 30.3 32.5 20.7 20.1 26.8 16.9 16.1 23.6 20.9 23.5 19.3 17.5 22.8 22.2 18.0 20.2 18.5 25.7 25.5 20.2 17.5 23.6 17.1 23.6 19.7 22.1 24.3 20.9 21.9 23.6 19.1 21.3 25.7 27.6 19.4 25.9 20.4 30.6 17.7 25.0 19.7 36.8 21.2 14.1 42.4 22.1 22.0 17.0 24.1 59.4 27.3 21.5 18.6 22.2 6.2 7.2 10.1 13.4 18.7 20.1 6.8 17.2 15.3 22.3 20.1 7.7 15.9 12.2 6.8 25.0 8.5 13.4 24.4 20.8 18.8 4.0 27.0 14.4 8.5 27.4 14.2 15.6 20.6 10.7 24.4 20.1 25.7 9.4 19.4 20.6 10.7 16.8 24.2 8.5 12.7 6.9 6.3 10.6 17.5 13.1 8.4 11.2 12.5 8.8 6.3 6.1 22.9 22.8 15.0 8.2 18.7 10.0 15.5 7.5 17.8 13.5 22.6 17.2 18.0 27.3 30.0 16.9 22.1 18.6 17.0 17.6 16.9 24.1 14.1 17.1 15.0 59.4 21.5 24.4 9.6 18.6 22.2 21.4 29.3 30.3 32.5 22.2 18.0 20.2 17.5 24.3 19.7 USP40 FLJ10785 ENSG00000085982 "Ubiquitin specific peptidase 40" Q9NVE5 2 233475520-233566782 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005821 Uncertain Approved Vesicles Vesicles "HPA005821: AB_1080526" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" "unprognostic (3.70e-1)" "unprognostic (2.15e-1)" "unprognostic (5.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (4.09e-2)" "unprognostic (1.90e-2)" "unprognostic (2.53e-2)" 12.5 20.5 11.0 8.2 17.7 3.5 16.1 8.2 13.5 12.4 12.1 26.1 22.5 11.6 16.2 28.1 13.9 13.4 13.2 10.8 11.3 8.5 16.9 15.7 13.9 7.6 22.1 10.1 19.6 17.2 22.8 24.3 16.3 16.5 16.1 11.2 16.4 13.9 19.7 13.6 21.7 15.2 17.1 20.1 11.4 16.3 23.3 18.9 9.8 21.2 9.4 12.0 18.0 11.8 1.9 5.0 0.4 2.8 1.4 2.2 1.4 9.6 11.3 10.4 7.0 15.3 14.3 9.1 9.6 7.4 8.9 9.7 8.0 11.6 0.2 2.8 15.4 17.3 7.9 17.0 12.8 0.0 5.1 7.7 9.3 13.6 13.3 3.2 5.2 13.6 12.3 13.1 18.5 10.2 12.3 1.9 12.5 7.8 3.4 4.7 4.6 9.2 0.0 21.5 4.5 10.6 15.7 5.7 6.2 7.6 7.9 9.8 9.0 7.2 10.1 12.5 7.8 5.2 11.5 3.5 2.6 0.4 16.1 5.8 10.7 0.0 2.7 0.0 1.3 2.8 0.6 1.3 1.5 1.3 4.0 1.9 1.9 2.2 0.4 1.4 2.3 5.0 2.0 1.4 11.0 17.7 8.2 13.5 11.3 8.5 22.1 10.1 16.5 18.9 USP41 ENSG00000161133 "Ubiquitin specific peptidase 41" Q3LFD5 22 20350578-20390758 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell line enhanced" "Detected in some" "NTERA-2: 1.6;RH-30: 4.1;RT4: 1.7;SCLC-21H: 4.9;SK-BR-3: 1.7;U-937: 1.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "unprognostic (4.01e-6)" "unprognostic (1.26e-1)" "unprognostic (1.44e-1)" "unprognostic (4.63e-3)" "unprognostic (7.44e-2)" "unprognostic (1.75e-1)" "unprognostic (5.28e-2)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (9.91e-5)" "unprognostic (3.43e-2)" "unprognostic (3.51e-2)" "unprognostic (2.54e-2)" "unprognostic (4.98e-2)" "unprognostic (1.40e-1)" "unprognostic (4.63e-1)" 0.7 0.3 0.4 0.0 0.6 1.0 0.6 0.0 1.8 0.3 0.3 1.6 0.2 0.0 0.2 0.2 0.0 0.1 0.4 0.4 0.1 0.9 1.3 0.1 0.2 0.1 0.2 0.0 0.4 0.1 0.4 0.2 0.5 0.0 0.7 0.1 0.3 0.0 0.3 0.3 2.0 0.3 0.4 0.3 0.3 0.1 0.4 1.2 0.3 0.4 0.4 0.5 0.1 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.0 1.6 0.4 0.0 4.1 0.0 0.0 1.7 4.9 0.2 0.0 1.7 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.8 1.2 1.5 0.3 0.0 0.0 0.3 0.2 0.2 0.4 0.4 0.1 0.5 0.1 0.2 0.0 0.2 0.0 0.4 0.4 1.2 0.4 0.1 USP42 FLJ12697 ENSG00000106346 "Ubiquitin specific peptidase 42" Q9H9J4 7 6104884-6161564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064800 Approved Nucleoplasm Nucleoplasm "HPA064800: " "unprognostic (1.48e-2)" "unprognostic (1.47e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-1)" "unprognostic (1.19e-2)" "unprognostic (3.32e-1)" "unprognostic (1.05e-1)" "unprognostic (2.82e-1)" "unprognostic (6.21e-3)" "unprognostic (2.47e-2)" "unprognostic (3.17e-3)" "unprognostic (3.14e-2)" "unprognostic (3.06e-2)" "unprognostic (2.19e-2)" "unprognostic (2.66e-1)" 6.7 5.6 5.7 5.7 9.5 19.8 7.2 14.1 10.6 8.5 7.4 10.4 5.5 8.1 14.1 7.0 6.9 8.1 6.5 5.4 5.8 6.0 7.4 7.1 7.3 6.5 6.7 4.9 10.6 11.7 10.5 10.9 8.2 6.2 7.4 6.5 8.9 6.6 6.3 7.4 9.2 9.2 8.7 9.9 7.8 6.7 25.2 8.1 14.3 7.7 6.2 8.3 7.6 6.9 1.9 2.2 3.3 2.4 1.9 4.3 0.8 8.3 6.2 11.3 11.0 6.5 5.0 7.7 4.5 5.8 5.4 5.3 4.4 4.4 9.9 3.0 5.6 7.8 9.4 5.0 5.8 2.4 7.3 4.6 5.3 4.5 5.5 10.6 5.3 5.8 5.9 5.7 7.4 6.5 17.6 6.7 3.5 7.4 6.4 12.0 12.7 4.8 12.2 8.8 6.8 5.0 4.4 8.6 15.3 5.8 12.0 3.6 5.5 5.5 5.5 4.8 17.8 6.0 5.4 6.0 5.0 8.6 4.0 6.5 9.4 2.3 1.1 3.3 2.1 2.4 3.0 1.9 2.6 1.3 1.1 1.1 1.7 4.3 1.4 1.9 1.2 2.2 1.8 0.8 5.7 9.5 14.1 10.6 5.8 6.0 6.7 4.9 6.2 8.1 USP43 FLJ30626 ENSG00000154914 "Ubiquitin specific peptidase 43" Q70EL4 17 9644698-9729691 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.6" "Cell line enhanced" "Detected in many" "BEWO: 12.3;SK-BR-3: 8.5;T-47d: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA023389, HPA027762" Uncertain "HPA023389: AB_1858691, HPA027762: AB_10603001" "unprognostic (1.39e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-3)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (2.04e-1)" "unprognostic (6.40e-3)" "unprognostic (2.26e-1)" "unprognostic (3.05e-3)" "unprognostic (2.41e-2)" "unprognostic (7.49e-2)" "unprognostic (5.95e-2)" "prognostic favourable (5.39e-4)" "unprognostic (3.24e-1)" "unprognostic (2.06e-1)" "unprognostic (3.28e-1)" 0.2 0.2 4.2 1.2 3.4 0.9 3.0 0.7 6.0 4.9 10.0 0.6 15.7 6.2 2.9 1.7 6.7 6.3 5.1 0.2 4.1 3.8 3.7 8.7 3.4 0.2 1.7 3.1 1.0 7.7 1.7 3.7 61.6 0.7 10.8 5.0 0.3 11.3 12.4 0.2 2.4 12.5 0.3 1.0 0.2 2.6 2.9 0.2 0.4 1.7 4.2 2.7 1.3 2.1 0.0 0.5 0.0 0.0 1.1 0.1 0.1 5.6 1.4 0.0 0.6 0.0 0.0 12.3 0.1 0.2 0.6 1.7 2.8 4.6 0.0 1.9 0.2 6.9 0.6 5.4 0.6 3.6 1.9 0.3 2.9 1.0 0.1 0.5 0.0 0.0 7.1 0.3 3.0 0.0 0.0 0.0 0.0 2.6 0.9 4.6 0.7 0.3 3.7 0.0 0.8 4.3 3.1 0.7 0.0 2.4 8.5 1.0 10.2 1.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 4.2 3.4 0.7 6.0 4.1 3.8 1.7 3.1 0.7 0.2 USP44 FLJ14528 ENSG00000136014 "Ubiquitin specific peptidase 44" Q9H0E7 12 95516560-95551490 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 26.8" "Cell line enriched" "Detected in some" 5 "NTERA-2: 54.8" "Cancer enhanced" "Detected in some" "testis cancer: 3.0" "Region enriched" "Detected in many" 5 "cerebellum: 10.9" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 8.6" "Group enriched" "Detected in many" 39 "B-cells: 5.6;T-cells: 8.6" "Low region specificity" "Detected in all" HPA026543 Approved "Nucleoli fibrillar center,Microtubules" "Nucleoli fibrillar center, Microtubules" "HPA026543: AB_1858692" "unprognostic (2.12e-2)" "unprognostic (1.14e-1)" "unprognostic (4.68e-2)" "unprognostic (1.01e-3)" "unprognostic (1.83e-4)" "unprognostic (7.18e-4)" "unprognostic (5.55e-2)" "unprognostic (1.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.73e-2)" "unprognostic (6.88e-2)" "unprognostic (2.97e-2)" "unprognostic (8.12e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-1)" "unprognostic (7.41e-2)" "unprognostic (7.07e-2)" 1.3 1.0 0.7 1.2 1.3 0.5 1.4 10.9 2.1 1.7 1.7 1.7 1.4 0.5 3.0 1.0 0.9 1.6 1.1 1.0 0.7 0.6 1.9 0.2 4.7 1.9 1.3 1.2 1.6 3.6 4.8 4.0 0.3 1.8 1.7 0.6 2.3 1.8 2.6 0.4 0.6 1.3 1.2 0.6 1.9 1.0 26.8 1.2 0.8 1.7 0.0 1.6 1.1 2.3 5.6 0.1 0.1 0.0 0.1 8.6 1.3 0.0 0.1 4.5 0.0 0.0 0.0 0.1 0.4 1.3 0.5 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.7 0.0 2.2 10.1 0.0 0.0 2.4 4.1 0.2 0.0 0.0 0.3 0.0 0.2 1.6 0.0 0.0 0.0 5.2 0.0 54.8 0.0 0.0 0.0 0.0 0.9 0.3 3.5 2.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.3 0.1 0.0 0.0 0.0 1.5 0.0 3.4 5.6 2.3 2.0 0.0 4.4 8.6 5.5 0.1 0.1 0.0 0.1 0.3 1.3 0.7 1.3 10.9 2.1 0.7 0.6 1.3 1.2 1.8 1.2 USP45 MGC14793 ENSG00000123552 "Ubiquitin specific peptidase 45" Q70EL2 6 99432379-99521728 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029602, HPA029604" Uncertain Approved Nucleoplasm,Cytosol "Nucleoplasm, Cytosol" "HPA029602: AB_10600418, HPA029604: AB_10602283" "unprognostic (7.81e-3)" "unprognostic (3.10e-3)" "unprognostic (1.63e-2)" "unprognostic (6.62e-2)" "unprognostic (1.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.15e-2)" "unprognostic (1.01e-1)" "unprognostic (2.77e-2)" "unprognostic (8.65e-2)" "unprognostic (2.95e-3)" "unprognostic (1.10e-1)" "unprognostic (3.43e-3)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" "unprognostic (1.43e-1)" "unprognostic (6.91e-2)" 9.8 9.1 8.5 10.2 12.2 7.2 9.0 28.4 11.6 9.0 9.7 8.6 8.9 13.7 15.7 9.6 10.0 8.1 11.9 11.5 7.7 8.5 12.2 9.0 7.1 12.7 9.8 8.0 10.7 9.6 10.2 21.7 9.6 15.0 9.9 13.1 7.9 9.8 8.4 14.6 11.8 12.4 10.8 10.6 9.9 8.9 5.7 9.4 7.1 10.7 10.4 9.5 8.8 15.0 8.6 5.1 3.7 2.5 2.6 6.2 1.4 4.1 3.0 5.9 8.3 10.9 10.4 6.2 7.2 8.1 7.6 10.8 6.1 4.6 11.1 5.4 7.3 5.6 9.0 7.2 10.5 8.7 8.6 10.8 5.9 4.8 8.4 10.0 6.2 11.1 5.7 6.8 11.6 11.2 26.0 11.0 7.1 3.9 3.2 9.5 9.5 6.4 4.7 4.4 6.2 10.5 4.9 8.3 6.8 5.1 6.8 5.3 3.6 4.9 11.2 4.2 5.3 6.1 11.0 4.7 4.3 20.3 7.2 9.5 7.4 3.7 2.0 0.6 4.9 1.3 6.2 7.4 4.2 5.6 3.5 8.6 3.0 2.9 0.5 2.6 2.5 5.1 3.5 1.4 8.5 12.2 28.4 11.6 7.7 8.5 9.8 8.0 15.0 9.4 USP46 FLJ12552 ENSG00000109189 "Ubiquitin specific peptidase 46" P62068 4 52590972-52659335 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Behavior, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, CAB076369, CAB076370" Uncertain Approved Nucleoli Nucleoli "CAB076369: , CAB076370: , HPA007288: AB_1080531" "unprognostic (1.15e-2)" "unprognostic (1.64e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (1.31e-1)" "unprognostic (1.41e-1)" "unprognostic (1.53e-3)" "unprognostic (1.59e-1)" "unprognostic (2.45e-2)" "unprognostic (1.80e-2)" "unprognostic (2.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (3.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.28e-1)" 4.7 9.5 26.0 3.5 20.9 2.8 7.0 23.7 29.4 8.9 4.2 12.8 5.2 4.8 7.2 6.2 12.4 7.8 5.8 28.9 21.9 19.0 10.8 3.1 4.4 3.7 19.1 13.9 12.3 5.6 12.2 5.3 10.6 12.7 7.7 4.6 5.3 8.0 7.8 13.7 8.0 4.5 5.5 18.9 3.5 6.3 12.2 15.0 1.0 10.0 4.3 5.8 7.3 5.7 1.4 4.4 2.0 1.4 1.2 3.9 1.0 5.3 3.8 12.3 9.1 13.5 16.9 13.6 8.8 7.1 6.5 5.5 7.6 4.2 3.5 10.4 8.7 3.1 21.4 10.2 12.0 3.1 7.5 5.5 3.6 8.5 13.5 7.3 6.5 14.4 9.6 6.7 6.3 9.6 5.4 5.0 13.8 4.9 3.1 3.8 9.1 4.6 7.9 9.0 0.7 14.0 9.9 7.4 8.9 4.3 14.7 8.5 5.4 5.5 8.9 6.4 14.0 7.5 13.2 5.2 2.4 2.8 9.9 4.4 7.9 2.0 1.4 0.3 2.3 1.2 1.7 1.4 3.9 2.0 2.8 1.2 0.9 0.8 0.3 1.2 0.9 4.4 1.2 1.0 26.0 20.9 23.7 24.3 21.9 19.0 19.1 13.9 12.7 15.0 USP47 ENSG00000170242 "Ubiquitin specific peptidase 47" Q96K76 11 11841423-11959323 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029286, HPA029289" Supported "HPA029286: AB_10599852, HPA029289: AB_10601675" "unprognostic (2.02e-1)" "unprognostic (2.72e-1)" "unprognostic (3.05e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (2.65e-2)" "unprognostic (2.27e-2)" "unprognostic (7.39e-2)" "unprognostic (1.54e-2)" "unprognostic (7.05e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-1)" "unprognostic (1.51e-1)" "unprognostic (9.96e-3)" "unprognostic (1.90e-1)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" 16.6 17.0 17.9 18.5 20.9 20.3 16.9 25.7 19.0 16.4 18.1 16.2 21.3 11.6 18.0 15.0 18.7 13.7 13.5 25.5 18.1 13.4 14.6 25.1 16.6 13.4 21.9 12.9 16.9 19.6 38.8 31.8 23.7 19.3 18.0 14.2 10.2 15.1 19.2 58.1 18.4 15.1 21.3 19.5 13.3 18.1 16.8 23.9 27.9 16.8 12.4 15.2 21.3 19.4 9.7 10.1 14.0 13.2 22.8 19.3 9.7 21.0 12.8 23.1 10.9 16.7 18.4 10.6 24.2 18.3 16.0 18.1 12.6 18.8 23.8 11.5 22.5 14.4 17.8 12.1 24.7 23.2 15.0 14.3 23.8 8.9 14.8 18.5 20.1 17.1 16.7 10.5 23.3 17.8 28.5 20.6 19.5 8.3 16.7 8.2 6.2 10.4 17.2 24.3 7.4 17.2 24.4 8.0 16.4 21.6 15.1 13.4 12.1 13.6 19.6 22.7 13.8 19.3 14.7 6.5 14.9 22.6 15.6 11.4 16.2 13.3 7.7 14.0 15.2 9.5 19.3 9.7 13.8 14.7 10.1 8.6 17.9 15.3 3.6 22.8 13.2 6.1 9.9 9.7 17.9 20.9 25.7 19.0 18.1 13.4 21.9 12.9 19.3 23.9 USP48 "FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31" ENSG00000090686 "Ubiquitin specific peptidase 48" Q86UV5 1 21678298-21783606 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030045, HPA030046" Approved Supported Nucleoplasm,Mitochondria,Cytosol Nucleoplasm "Mitochondria, Cytosol" "HPA030045: AB_10670833, HPA030046: AB_10603325" "unprognostic (1.35e-1)" "unprognostic (3.72e-1)" "unprognostic (5.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.23e-1)" "unprognostic (7.00e-3)" "prognostic unfavourable (6.09e-8)" "unprognostic (1.04e-2)" "unprognostic (3.01e-3)" "unprognostic (9.30e-2)" "unprognostic (7.54e-2)" "unprognostic (4.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-1)" "unprognostic (5.70e-2)" "unprognostic (2.80e-2)" 20.1 38.8 18.6 28.9 30.9 30.9 22.1 48.2 27.5 19.9 18.4 25.6 15.4 17.6 21.3 17.6 19.0 17.4 20.5 17.8 16.9 15.8 15.5 18.3 18.3 26.2 26.6 22.5 27.0 19.8 24.6 35.4 23.1 26.8 21.6 22.0 22.1 24.5 16.3 17.0 23.9 22.2 22.2 19.7 29.1 26.2 15.8 23.6 25.8 23.9 14.0 29.0 19.8 21.0 13.7 10.5 33.7 9.6 5.6 11.2 5.6 14.6 7.0 16.5 11.9 14.3 17.7 16.3 18.5 12.6 12.4 16.5 6.4 15.0 16.5 12.5 16.7 13.6 20.3 14.9 18.9 16.0 13.9 35.3 26.1 11.6 12.8 17.7 18.9 14.3 12.9 12.6 14.1 36.6 27.7 46.8 15.2 7.3 14.6 23.0 10.4 12.6 20.6 16.6 19.3 14.3 12.4 20.1 12.5 17.4 16.0 41.8 8.2 21.4 25.9 13.4 11.1 16.4 10.7 37.5 26.6 16.4 12.9 22.0 19.7 33.7 9.6 16.7 6.4 4.6 7.6 13.7 9.5 9.5 10.5 12.8 11.2 7.0 8.9 5.6 5.0 7.7 10.1 5.6 18.6 30.9 48.2 27.5 16.9 15.8 26.6 22.5 26.8 23.6 USP49 MGC20741 ENSG00000164663 "Ubiquitin specific peptidase 49" Q70CQ1 6 41789896-41895361 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 23.4;U-698: 33.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030254, HPA030255" Uncertain "HPA030254: AB_10600198, HPA030255: AB_10601218" "unprognostic (1.71e-1)" "unprognostic (4.86e-3)" "unprognostic (1.93e-1)" "unprognostic (2.57e-4)" "unprognostic (4.46e-2)" "unprognostic (2.84e-4)" "unprognostic (7.17e-3)" "unprognostic (5.06e-2)" "unprognostic (1.19e-2)" "unprognostic (3.22e-1)" "unprognostic (5.59e-3)" "unprognostic (8.28e-2)" "unprognostic (1.26e-5)" "unprognostic (5.39e-2)" "unprognostic (4.58e-2)" "unprognostic (4.37e-3)" "unprognostic (3.24e-3)" 2.4 2.4 7.6 3.5 6.0 7.3 2.7 12.7 9.3 2.3 1.9 2.0 4.3 2.2 4.0 2.3 1.8 2.2 2.1 3.5 7.6 4.2 1.6 1.7 2.4 3.7 3.0 5.8 4.0 3.2 2.6 4.8 1.8 4.2 2.4 2.1 3.7 2.7 2.4 3.8 4.1 2.2 3.2 3.2 3.5 2.2 7.4 3.2 7.3 7.7 0.6 3.4 2.8 2.0 1.2 0.7 8.5 1.8 0.8 0.9 0.4 3.0 0.9 12.3 6.0 1.5 1.6 5.1 1.1 1.1 1.8 2.2 3.9 0.7 12.4 1.3 1.5 1.3 7.6 1.1 2.7 3.0 5.6 4.4 4.6 1.3 1.0 3.4 2.7 1.6 0.9 2.6 1.7 1.1 9.2 3.4 1.4 1.7 13.1 5.2 3.4 1.1 23.4 6.0 2.7 0.7 2.1 8.3 3.4 1.6 0.6 0.6 1.8 3.1 3.1 4.3 4.2 1.4 1.5 6.4 5.6 33.3 0.5 3.5 0.8 8.5 1.3 1.4 0.8 1.5 0.4 1.2 0.4 0.8 0.5 0.9 0.9 0.7 2.4 0.8 1.8 0.7 0.4 0.4 7.6 6.0 12.7 9.3 7.6 4.2 3.0 5.8 4.2 3.2 USP5 IsoT ENSG00000111667 "Ubiquitin specific peptidase 5" P45974 12 6852128-6866632 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006756 Uncertain Approved Nucleoplasm,Cytosol 820000 "Nucleoplasm, Cytosol" "HPA006756: AB_1080534" "unprognostic (2.19e-1)" "unprognostic (5.83e-2)" "unprognostic (2.48e-1)" "unprognostic (2.57e-1)" "unprognostic (7.60e-2)" "unprognostic (2.21e-2)" "unprognostic (4.02e-2)" "unprognostic (3.93e-2)" "unprognostic (2.57e-1)" "unprognostic (4.71e-2)" "unprognostic (8.90e-3)" "unprognostic (4.69e-2)" "unprognostic (1.17e-2)" "unprognostic (2.65e-2)" "unprognostic (3.56e-1)" "unprognostic (3.23e-1)" "unprognostic (2.02e-3)" 18.6 28.7 23.1 17.8 32.6 13.6 12.9 24.6 50.9 15.9 21.5 26.8 13.8 17.6 22.3 12.8 27.7 19.1 14.7 22.4 23.9 28.6 14.9 24.8 14.4 18.6 23.6 33.2 14.4 13.2 29.7 19.6 21.7 36.8 19.5 16.1 11.6 14.1 22.7 41.2 33.5 18.1 25.3 23.6 14.1 15.9 30.9 18.7 22.8 19.2 20.4 19.9 21.3 16.0 10.8 18.6 5.3 16.6 10.8 17.1 16.6 25.3 39.7 26.7 30.2 18.2 16.8 34.1 27.6 21.2 33.0 24.1 37.5 25.2 30.7 14.5 28.6 22.4 29.3 27.4 21.2 57.5 24.8 28.1 31.9 20.3 14.2 25.4 29.6 16.9 15.9 28.5 19.8 28.2 24.1 12.3 27.2 27.8 38.1 12.6 52.0 16.8 30.0 34.8 21.2 18.8 24.7 14.7 29.7 18.8 28.7 12.0 11.5 20.8 27.3 28.0 33.9 21.3 34.3 14.9 34.2 46.7 31.2 16.2 27.2 2.3 12.3 5.3 17.1 16.6 16.1 10.8 15.2 14.4 18.6 10.0 14.6 14.8 0.9 10.8 14.7 13.6 12.9 16.6 23.1 32.6 24.6 50.9 23.9 28.6 23.6 33.2 36.8 18.7 USP51 ENSG00000247746 "Ubiquitin specific peptidase 51" Q70EK9 X 55484616-55489202 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 34.1" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in some" "eosinophil: 2.4;naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA001942 Uncertain Approved "Nucleoli fibrillar center,Cytosol" Cytosol "Nucleoli fibrillar center" "HPA001942: AB_1080536" "unprognostic (1.19e-2)" "unprognostic (4.65e-2)" "unprognostic (3.67e-2)" "unprognostic (1.02e-3)" "unprognostic (8.08e-2)" "unprognostic (3.26e-1)" "unprognostic (3.17e-3)" "unprognostic (2.07e-3)" "unprognostic (5.69e-2)" "prognostic favourable (5.70e-4)" "unprognostic (1.01e-3)" "unprognostic (1.27e-1)" "prognostic favourable (2.63e-5)" "unprognostic (2.81e-3)" "unprognostic (5.92e-2)" "unprognostic (5.85e-2)" "unprognostic (1.63e-1)" 0.6 2.7 2.0 0.3 2.9 0.1 0.9 2.3 1.8 1.4 0.6 0.0 1.8 34.1 0.2 3.4 0.3 1.0 1.8 3.7 2.2 0.5 0.7 0.4 1.6 4.1 0.8 3.6 1.8 1.3 1.3 0.3 0.3 1.5 0.0 0.5 0.5 1.1 1.4 0.9 0.3 1.3 3.2 0.5 0.7 0.5 0.9 0.0 2.4 0.0 0.6 2.4 0.1 0.0 0.9 5.7 1.7 2.9 1.5 0.0 0.9 0.5 1.1 1.3 1.8 0.8 0.0 6.9 1.2 0.3 1.5 0.6 1.8 1.8 0.1 1.5 0.3 0.0 1.2 3.5 0.3 5.9 0.1 0.6 0.0 0.4 4.4 4.4 0.9 3.8 3.4 1.8 7.2 0.3 4.9 1.1 2.2 1.4 0.2 0.0 1.1 1.6 0.2 5.4 1.4 1.8 0.3 2.3 3.1 0.6 0.2 7.0 2.7 1.4 1.5 2.0 1.5 0.0 0.0 2.4 0.3 0.0 0.0 0.6 0.6 0.0 0.0 0.9 2.4 0.2 0.0 0.6 0.0 0.0 0.0 0.1 USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116438-5175034 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "skeletal muscle: 18.2;testis: 29.0" "Low cell line specificity" "Detected in many" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046969 Uncertain Vesicles Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" 0.3 0.3 0.3 0.3 0.6 0.2 0.4 0.5 0.5 0.3 0.5 0.3 1.2 0.0 0.6 0.6 0.3 0.5 0.4 0.3 0.3 0.1 0.3 0.3 0.3 0.3 0.3 0.3 2.6 0.3 0.0 0.4 0.4 0.3 0.4 0.1 0.3 0.3 0.3 18.2 0.6 0.7 0.9 0.3 0.3 0.0 29.0 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.9 1.2 1.9 1.0 0.2 0.4 0.1 2.2 1.0 2.2 1.7 0.4 0.2 2.3 1.9 0.1 0.6 0.4 0.8 1.1 2.2 1.7 1.3 1.0 0.7 0.8 0.5 1.6 1.3 1.7 1.3 0.9 1.2 0.5 2.9 1.1 0.5 0.1 0.2 0.3 0.5 0.3 0.5 2.5 1.9 0.7 1.6 0.1 1.4 2.0 0.2 0.5 0.7 0.9 2.2 1.0 0.1 3.3 2.2 2.2 1.2 1.0 3.3 2.1 1.4 2.0 1.7 1.5 0.0 0.1 2.7 0.1 0.4 0.9 0.4 0.3 0.2 0.6 0.3 0.3 0.3 0.9 0.3 0.4 1.9 0.2 1.0 1.2 0.1 0.1 0.3 0.6 0.5 0.3 0.3 0.1 0.3 0.3 0.3 0.3 USP7 HAUSP ENSG00000187555 "Ubiquitin specific peptidase 7" Q93009 16 8892094-8964514 "Enzymes, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" "Developmental protein, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008108, HPA015641" Approved "CAB008108: AB_2233500, HPA015641: AB_1858700" "unprognostic (6.73e-2)" "unprognostic (1.59e-1)" "unprognostic (3.36e-3)" "unprognostic (1.94e-2)" "unprognostic (9.64e-2)" "unprognostic (8.09e-2)" "unprognostic (4.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.81e-1)" "unprognostic (2.49e-1)" "unprognostic (2.35e-1)" "unprognostic (9.93e-2)" "prognostic favourable (8.56e-5)" "unprognostic (1.35e-1)" "unprognostic (1.07e-1)" "unprognostic (7.31e-2)" "unprognostic (2.69e-1)" 17.8 16.8 23.9 25.8 22.9 37.6 21.3 28.7 24.5 21.2 26.3 16.2 18.4 17.7 23.5 16.4 24.4 20.3 18.7 23.7 22.8 20.8 16.5 21.3 21.0 30.5 19.6 22.6 22.5 24.0 44.4 19.7 19.3 16.2 18.5 27.4 16.0 18.4 20.3 42.2 25.2 21.5 22.7 15.3 22.9 22.6 43.3 16.5 68.8 19.5 22.3 35.1 23.9 31.7 7.5 9.8 5.5 7.8 3.9 8.7 1.8 12.7 23.7 21.0 15.7 11.9 15.3 14.5 17.6 15.1 16.5 14.0 21.2 15.6 30.7 11.2 20.3 15.9 32.1 21.0 27.6 20.1 12.8 25.5 16.0 43.8 17.3 28.0 16.5 13.2 13.3 17.9 21.2 23.3 24.6 34.1 16.7 24.3 41.1 5.4 14.7 13.8 36.6 23.6 28.0 11.5 25.0 19.8 12.2 19.7 18.5 9.7 18.5 12.6 19.9 17.8 18.2 27.3 13.1 16.5 40.4 47.0 16.6 16.4 14.3 5.5 3.3 3.8 7.1 3.2 8.7 5.9 6.6 8.2 3.3 7.5 8.0 6.8 5.2 3.9 7.8 9.8 7.0 1.8 23.9 22.9 28.7 24.5 22.8 20.8 19.6 22.6 16.2 16.5 USP8 "HumORF8, KIAA0055, SPG59, UBPY" ENSG00000138592 "Ubiquitin specific peptidase 8" P40818 15 50424380-50514419 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050215 Approved Supported "Golgi apparatus,Cytosol" "Golgi apparatus" Cytosol "HPA050215: " "unprognostic (5.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "unprognostic (9.58e-2)" "unprognostic (2.35e-2)" "unprognostic (2.91e-1)" "unprognostic (1.42e-1)" "unprognostic (3.96e-1)" "unprognostic (1.68e-2)" "unprognostic (5.08e-2)" "unprognostic (2.94e-1)" "unprognostic (3.99e-2)" "prognostic favourable (1.29e-5)" "unprognostic (4.89e-2)" "unprognostic (1.13e-1)" "unprognostic (3.79e-1)" "unprognostic (1.58e-1)" 19.4 21.9 21.0 20.6 20.6 21.6 18.1 27.3 21.6 21.4 23.9 13.8 19.5 20.2 22.1 17.4 22.3 17.4 15.5 17.4 19.7 18.2 28.2 26.4 17.0 25.4 21.8 15.2 21.9 16.7 42.6 43.2 29.1 29.7 16.7 18.9 10.7 19.9 17.9 24.3 17.8 32.1 19.2 29.3 30.3 17.7 27.5 26.1 28.9 24.1 12.7 20.9 22.3 18.4 16.7 10.6 38.1 15.1 9.5 11.9 6.9 11.0 15.9 8.9 15.7 16.3 18.3 12.4 15.9 18.9 15.5 18.4 10.6 7.3 11.7 12.3 18.2 21.5 12.2 11.9 18.4 10.2 8.1 21.6 14.8 10.9 16.8 14.4 14.6 14.2 14.3 13.7 23.3 15.0 12.3 14.2 14.5 22.7 9.2 5.7 10.2 7.3 8.4 16.6 17.5 14.7 26.1 11.4 10.4 16.8 25.1 20.8 13.7 17.7 17.0 16.1 9.1 49.6 21.0 11.1 23.1 12.9 12.9 29.2 15.5 38.1 13.3 22.4 11.1 12.4 10.7 16.5 11.4 11.1 10.6 16.7 11.9 10.7 22.7 9.5 15.1 9.9 8.5 6.9 21.0 20.6 27.3 21.6 19.7 18.2 21.8 15.2 29.7 26.1 USP9X "DFFRX, FAF, MRX99" ENSG00000124486 "Ubiquitin specific peptidase 9, X-linked" Q93008 X 41085635-41236579 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Chromosome partition, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011618, HPA047417, CAB070164" Approved Uncertain Vesicles Vesicles "CAB011618: AB_470860, CAB070164: AB_10011071, HPA047417: " "unprognostic (5.42e-3)" "unprognostic (6.42e-2)" "unprognostic (3.19e-3)" "unprognostic (2.94e-2)" "unprognostic (5.99e-2)" "unprognostic (4.76e-1)" "unprognostic (1.82e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.07e-2)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" 18.0 21.8 17.7 14.0 15.9 15.5 16.8 16.6 16.7 18.4 20.6 11.4 25.4 13.2 19.6 19.0 17.3 17.0 17.1 20.9 14.2 14.2 18.5 34.2 16.7 23.1 15.2 15.4 15.7 16.5 45.8 17.0 41.1 12.9 13.4 14.4 13.9 14.2 25.2 42.8 14.8 22.0 17.3 14.0 16.7 16.9 16.9 14.0 21.1 20.3 17.6 16.5 20.3 19.9 6.4 5.5 13.0 5.0 4.9 7.8 3.1 19.0 22.6 20.1 20.5 16.9 17.7 4.6 11.0 14.8 12.5 14.6 10.4 8.9 12.8 6.2 25.0 12.9 34.5 20.0 21.1 16.1 24.8 14.9 21.9 9.3 14.3 12.9 10.9 15.3 9.0 30.0 28.5 19.3 18.0 10.5 19.3 14.0 9.2 5.1 21.2 12.5 10.1 27.5 8.3 11.9 15.8 11.4 10.7 46.2 12.8 12.6 12.4 7.2 20.6 19.2 14.8 18.1 11.8 9.6 11.2 16.4 13.7 5.8 9.5 3.3 4.7 6.0 5.6 4.2 7.8 6.4 6.6 6.2 5.5 4.7 6.7 6.0 13.0 4.9 5.0 4.2 5.6 3.1 17.7 15.9 16.6 16.7 14.2 14.2 15.2 15.4 12.9 14.0 USP9Y DFFRY ENSG00000114374 "Ubiquitin specific peptidase 9, Y-linked" O00507 Y 12701231-12860839 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 16.0;RT4: 8.6" "Cancer enhanced" "Detected in many" "prostate cancer: 5.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.4;dendritic cells: 2.0;T-cells: 2.7" "Not detected" "Not detected" HPA057687 Uncertain Vesicles Vesicles "HPA057687: " "unprognostic (2.63e-1)" "unprognostic (8.97e-2)" "unprognostic (1.10e-5)" "unprognostic (8.46e-3)" "unprognostic (4.93e-2)" "unprognostic (2.53e-2)" "unprognostic (2.77e-1)" "unprognostic (3.17e-2)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-4)" "unprognostic (2.28e-1)" "unprognostic (1.19e-2)" "unprognostic (1.42e-1)" 1.2 2.2 1.4 0.9 3.1 1.7 1.1 9.6 4.0 0.0 1.6 1.4 0.0 8.6 4.4 0.0 3.8 2.4 1.8 3.4 2.9 2.2 2.2 1.4 2.1 0.0 2.7 0.0 4.8 1.7 9.3 4.8 2.3 7.6 2.8 2.0 1.8 0.0 1.5 2.2 1.5 2.9 2.8 4.5 3.2 0.0 2.4 2.0 0.1 0.2 0.5 2.7 0.2 0.0 2.2 0.0 0.0 0.0 0.0 2.4 7.1 7.1 3.6 3.9 0.0 0.0 4.0 0.0 5.9 0.0 0.0 0.0 3.2 2.2 0.0 2.5 0.0 7.0 4.0 0.0 0.0 5.9 5.2 0.0 0.0 0.0 0.0 0.0 6.4 0.0 4.0 0.0 1.5 0.0 0.0 2.0 0.8 16.0 8.6 2.8 0.0 0.0 0.0 2.1 0.0 0.0 5.5 4.4 0.0 0.0 3.2 0.0 3.7 7.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.2 2.7 1.2 2.2 1.5 0.3 2.4 2.2 1.3 0.1 0.5 0.0 2.0 1.6 0.2 VCP "CDC48, IBMPFD, p97, TERA" ENSG00000165280 "Valosin containing protein" P55072 9 35056064-35073249 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, DNA damage, DNA repair, Transport, Ubl conjugation pathway" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005593, HPA012728, HPA012814" Supported Enhanced Nucleoplasm,Cytosol 110000000 "Nucleoplasm, Cytosol" "CAB005593: AB_2214638, HPA012728: AB_1858730, HPA012814: AB_1858729" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.15e-2)" "prognostic favourable (7.30e-4)" "unprognostic (5.78e-2)" "unprognostic (1.87e-1)" "unprognostic (2.52e-3)" "unprognostic (1.13e-2)" "unprognostic (3.82e-2)" "unprognostic (1.81e-2)" "unprognostic (2.19e-2)" "unprognostic (3.24e-1)" "prognostic favourable (9.63e-7)" "unprognostic (1.83e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-1)" "unprognostic (9.11e-2)" 33.7 43.6 19.6 30.3 21.8 30.8 31.4 19.4 31.0 32.2 25.7 22.7 32.9 22.2 30.5 34.0 40.0 24.7 33.8 69.6 20.0 23.4 30.1 63.4 27.6 42.7 23.1 21.1 25.0 34.9 44.5 29.0 46.3 26.3 33.4 26.5 21.2 30.7 34.1 80.4 29.2 26.3 29.2 23.0 37.8 28.9 25.6 18.2 43.3 32.1 42.2 35.7 31.5 26.5 25.9 29.4 43.4 30.6 23.0 32.1 34.4 36.0 41.2 28.4 15.3 34.3 24.2 21.7 33.6 38.1 50.3 37.2 27.5 14.9 28.6 29.5 41.7 17.4 42.3 40.1 43.6 30.7 24.5 19.9 38.9 37.6 26.6 22.3 26.6 27.6 27.0 43.5 19.5 54.3 20.6 20.8 40.1 25.4 21.8 53.7 37.0 39.4 19.4 22.1 17.7 39.3 25.8 15.5 19.5 20.3 23.0 10.2 18.5 15.9 44.4 20.2 26.1 17.9 29.4 10.6 22.4 24.5 33.1 16.1 25.8 43.4 24.5 31.9 24.7 27.2 23.8 25.9 23.6 24.8 29.4 21.1 17.7 18.5 28.4 23.0 30.6 18.9 32.1 34.4 19.6 21.8 19.4 31.0 20.0 23.4 23.1 21.1 26.3 18.2 VCPIP1 "DUBA3, FLJ23132, KIAA1850, VCIP135" ENSG00000175073 "Valosin containing protein interacting protein 1" Q96JH7 8 66628487-66667217 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023932 Uncertain Approved "Plasma membrane,Centrosome" "Plasma membrane" Centrosome "HPA023932: " "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (4.01e-2)" "unprognostic (5.56e-2)" "unprognostic (5.23e-2)" "unprognostic (7.21e-2)" "unprognostic (2.80e-1)" "unprognostic (3.96e-1)" "unprognostic (5.23e-3)" "unprognostic (7.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-2)" "unprognostic (8.58e-3)" 9.5 8.7 15.7 12.6 14.5 30.9 8.9 14.4 15.1 7.5 8.4 7.0 3.8 7.0 7.8 8.7 8.1 6.9 7.0 6.7 10.2 9.2 8.3 12.3 10.5 13.6 10.3 13.7 7.8 9.0 14.0 5.9 8.0 12.3 7.0 7.8 6.0 9.0 7.1 14.8 7.3 10.0 6.3 9.6 14.7 8.0 10.8 11.7 11.6 8.0 2.8 13.3 7.9 7.0 2.6 3.4 11.3 8.8 2.8 4.3 1.7 8.8 8.0 4.2 5.5 12.7 9.0 4.0 7.1 7.2 5.5 6.3 4.7 8.4 11.9 2.1 9.5 7.9 6.7 5.9 7.9 8.9 4.8 13.3 7.9 5.9 7.7 4.4 14.3 9.7 8.8 5.9 10.8 5.9 8.9 11.6 8.0 4.3 9.5 7.6 7.9 5.6 6.1 6.5 6.0 7.9 7.0 2.4 4.7 5.5 8.4 6.1 8.6 7.3 11.8 7.2 5.4 6.3 4.7 10.3 5.0 12.8 7.2 6.4 5.4 9.2 3.2 6.7 4.3 5.2 3.6 2.0 2.7 3.1 3.4 2.6 2.2 2.9 11.3 2.8 8.8 1.3 3.3 1.7 15.7 14.5 14.4 15.1 10.2 9.2 10.3 13.7 12.3 11.7 VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132681590-132714049 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 131.9;liver: 112.2" "Cell line enhanced" "Detected in some" "A-431: 4.0;CAPAN-2: 4.2;EFO-21: 14.8;HBEC3-KT: 3.9;LHCN-M2: 4.2" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "classical monocyte: 13.4" "Group enriched" "Detected in many" 71 "dendritic cells: 4.9;granulocytes: 8.0;monocytes: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA064145 Uncertain "Intracellular and membrane" 1100000000 "HPA064145: " "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavourable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" 1.8 0.4 0.3 0.6 0.3 2.4 0.7 0.2 0.3 0.4 128.6 0.1 0.0 40.6 2.5 0.2 0.6 1.7 27.0 1.1 0.3 0.3 6.5 112.2 7.9 2.4 0.4 0.1 0.4 0.9 0.0 0.3 1.0 0.5 0.4 0.3 0.2 1.5 0.1 0.4 0.5 131.9 0.0 0.5 5.6 0.8 0.5 0.1 0.2 0.4 0.0 0.4 0.4 0.9 0.1 4.9 8.0 13.4 0.0 0.0 3.6 4.0 0.0 0.5 0.1 0.1 1.3 0.9 0.3 0.3 0.0 0.0 0.1 4.2 0.2 14.8 0.0 0.1 0.0 3.9 1.0 0.1 0.0 0.2 0.2 2.3 2.3 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 4.2 0.2 0.0 0.6 0.1 0.2 0.1 0.2 1.7 0.9 0.3 0.2 0.6 0.1 0.0 0.0 0.0 0.0 2.6 1.0 0.1 0.4 0.2 0.4 0.0 0.1 0.4 0.1 0.6 2.3 13.4 0.0 0.0 7.4 0.0 0.0 0.0 0.0 4.9 0.1 0.0 0.0 8.0 0.0 10.2 0.2 0.0 3.6 0.3 0.3 0.2 0.3 0.3 0.3 0.4 0.1 0.5 0.1 VNN2 "FOAP-4, GPI-80" ENSG00000112303 "Vanin 2" O95498 6 132743870-132763459 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 85.2;lung: 36.4;lymphoid tissue: 43.6" "Cell line enriched" "Detected in some" 8 "Daudi: 34.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 8 "neutrophil: 85.2" "Lineage enriched" "Detected in all" 8 "granulocytes: 85.2" "Low region specificity" "Detected in single" 270000 "unprognostic (2.13e-1)" "unprognostic (1.15e-1)" "unprognostic (9.60e-3)" "unprognostic (5.71e-2)" "unprognostic (2.14e-1)" "unprognostic (5.61e-3)" "unprognostic (1.98e-3)" "unprognostic (4.38e-1)" "unprognostic (3.07e-1)" "unprognostic (3.46e-1)" "unprognostic (2.84e-1)" "unprognostic (8.30e-2)" "prognostic unfavourable (2.72e-7)" "unprognostic (1.62e-1)" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (5.45e-2)" 10.1 1.4 1.1 9.5 1.1 10.8 1.4 1.4 1.4 1.8 1.9 0.8 0.0 0.7 0.9 3.1 2.1 4.3 10.2 10.5 1.1 1.1 2.8 5.6 36.4 39.8 3.8 0.3 2.1 2.4 0.0 1.2 8.6 1.5 2.4 0.9 1.8 1.3 0.2 1.0 0.7 3.6 2.4 2.2 43.6 2.8 3.6 0.6 3.4 1.4 0.7 17.7 7.3 10.9 6.4 2.2 85.2 10.9 5.8 6.7 5.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 0.6 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.9 0.0 0.0 1.5 10.9 0.0 4.2 2.4 1.7 6.4 1.4 4.9 2.2 5.5 4.5 6.7 85.2 5.8 1.5 0.4 0.9 5.7 1.1 1.1 1.4 1.4 1.1 1.1 3.8 0.3 1.5 0.6 VNN3 HSA238982 ENSG00000093134 "Vanin 3" Q9NY84 6 132722787-132734765 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "blood: 39.5;bone marrow: 29.8;liver: 29.4" "Cell line enhanced" "Detected in some" "Daudi: 2.5;EFO-21: 3.7;hTCEpi: 2.3" "Cancer enhanced" "Detected in some" "liver cancer: 3.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "neutrophil: 39.5" "Lineage enriched" "Detected in single" 40 "granulocytes: 39.5" "Secreted to blood" 150000000 "unprognostic (3.20e-2)" "unprognostic (2.70e-1)" "unprognostic (7.92e-3)" "unprognostic (1.71e-2)" "unprognostic (3.05e-3)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.01e-1)" "unprognostic (2.42e-2)" "unprognostic (7.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (5.84e-8)" "unprognostic (1.25e-2)" "unprognostic (1.52e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" 1.1 0.1 0.4 3.3 0.4 29.8 0.2 0.2 0.6 2.4 1.2 0.2 0.2 0.0 0.2 0.8 0.9 2.4 1.3 1.0 0.4 0.0 0.3 29.4 6.1 1.2 0.4 0.2 1.2 0.2 0.0 0.2 5.8 0.3 0.5 0.0 0.4 1.1 0.2 0.2 0.1 0.2 0.2 0.2 7.6 0.4 0.3 0.2 0.2 0.3 2.4 0.7 0.6 0.3 0.0 0.0 39.5 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 2.5 3.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 6.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.5 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.2 0.6 0.4 0.0 0.4 0.2 0.3 0.2 VPS4A "FLJ22197, SKD1, SKD1A, SKD2, VPS4, VPS4-1" ENSG00000132612 "Vacuolar protein sorting 4 homolog A" Q9UN37 16 69311356-69326939 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "CAB018751, CAB034411, HPA060092" Approved Supported Midbody Midbody "CAB018751: AB_2215497, CAB034411: AB_2304400, HPA060092: " "unprognostic (2.60e-2)" "unprognostic (2.32e-2)" "unprognostic (1.26e-1)" "unprognostic (9.26e-2)" "unprognostic (4.03e-1)" "unprognostic (1.20e-1)" "unprognostic (2.55e-2)" "unprognostic (2.70e-2)" "unprognostic (4.63e-2)" "unprognostic (8.61e-2)" "unprognostic (3.91e-3)" "unprognostic (2.19e-1)" "prognostic favourable (1.76e-4)" "unprognostic (5.44e-2)" "unprognostic (1.46e-1)" "unprognostic (2.61e-1)" "unprognostic (6.79e-2)" 20.2 19.6 24.8 14.4 26.5 13.0 24.2 28.7 35.6 12.9 17.8 19.3 14.5 22.0 16.6 14.5 26.3 16.0 16.1 34.3 24.4 22.8 23.2 13.7 15.8 17.5 25.4 29.3 21.0 31.4 29.7 9.6 16.6 33.6 17.5 13.2 15.6 30.4 15.5 81.6 24.3 20.5 18.4 34.3 15.0 18.9 15.5 17.4 8.9 27.5 21.1 13.0 15.6 21.2 11.1 11.6 15.7 13.1 9.3 18.1 14.4 10.9 18.8 13.1 17.1 11.8 10.5 11.4 15.0 13.6 19.9 13.4 17.7 10.3 18.6 14.9 14.8 16.5 12.9 15.1 12.0 7.8 16.7 11.7 11.3 14.3 18.3 14.5 10.9 12.1 19.8 17.2 15.8 14.7 19.3 5.6 14.6 24.5 18.8 11.0 14.7 13.3 25.5 10.5 21.8 10.0 9.0 21.7 13.9 31.9 10.0 11.4 17.4 11.0 17.5 18.4 11.6 16.7 11.6 20.3 16.0 33.8 16.9 9.9 20.2 10.0 11.6 15.7 14.6 10.2 13.3 11.1 12.3 18.1 11.6 10.1 14.3 13.0 9.5 9.3 13.1 6.8 13.8 14.4 24.8 26.5 28.7 35.6 24.4 22.8 25.4 29.3 33.6 17.4 VPS4B "SKD1, SKD1B, VPS4-2" ENSG00000119541 "Vacuolar protein sorting 4 homolog B" O75351 18 63389190-63422483 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040393, CAB046445, HPA057649" Approved Approved "Vesicles,Intermediate filaments" 34000 Vesicles "Intermediate filaments" "CAB046445: AB_10603252, HPA040393: , HPA057649: " "unprognostic (8.54e-2)" "unprognostic (1.06e-1)" "unprognostic (1.85e-3)" "unprognostic (5.59e-2)" "unprognostic (1.71e-1)" "unprognostic (9.47e-2)" "unprognostic (1.75e-1)" "unprognostic (1.79e-1)" "unprognostic (4.54e-2)" "unprognostic (9.10e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "prognostic favourable (1.23e-4)" "unprognostic (4.59e-1)" "unprognostic (1.40e-1)" "unprognostic (4.08e-1)" "unprognostic (1.21e-1)" 16.8 13.0 14.3 14.3 17.2 28.0 17.2 15.4 19.1 19.8 24.0 21.8 15.5 20.0 16.7 12.1 55.0 13.1 15.1 9.9 13.7 16.0 15.6 20.5 14.3 21.6 17.0 14.7 11.9 14.0 17.5 17.4 27.4 23.4 14.3 22.2 9.3 21.8 15.0 9.9 22.1 28.7 15.2 20.2 17.3 18.7 9.0 14.6 27.8 17.0 17.6 31.8 18.6 24.7 20.7 13.6 56.4 20.6 19.1 18.9 15.4 18.4 6.8 7.6 8.3 11.8 16.7 13.2 16.2 15.3 12.4 13.6 5.0 13.2 17.8 10.6 11.8 40.1 9.1 17.7 16.5 12.9 7.3 8.9 9.6 7.7 16.9 30.6 19.5 15.1 27.6 10.9 19.5 11.5 4.4 16.7 17.6 6.4 19.1 9.6 7.9 10.7 16.0 16.2 17.1 15.6 21.7 13.0 11.5 12.2 12.0 18.1 11.5 16.7 17.6 19.2 9.4 7.2 10.6 56.1 26.9 22.9 11.0 14.5 14.2 39.4 16.8 36.0 16.5 16.6 15.4 18.9 17.4 17.0 13.6 20.7 15.8 16.6 56.4 19.1 20.6 13.6 18.9 15.4 14.3 17.2 15.4 19.1 13.7 16.0 17.0 14.7 23.4 14.6 WDYHV1 "C8orf32, FLJ10204" ENSG00000156795 "WDYHV motif containing 1" Q96HA8 8 123416725-123467230 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024823, HPA053680" Approved Supported Nucleoplasm,Vesicles Nucleoplasm Vesicles "HPA024823: AB_1845773, HPA053680: " "unprognostic (9.97e-2)" "unprognostic (4.82e-2)" "unprognostic (3.48e-1)" "prognostic unfavourable (4.93e-5)" "unprognostic (1.69e-1)" "unprognostic (5.00e-2)" "prognostic unfavourable (3.47e-4)" "unprognostic (1.93e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.81e-2)" "unprognostic (1.26e-1)" "unprognostic (5.39e-2)" "unprognostic (7.46e-2)" "unprognostic (2.37e-1)" 10.5 15.5 13.2 7.9 13.6 6.3 17.2 14.3 16.8 14.5 9.9 13.9 10.7 5.8 11.2 12.0 10.2 9.8 8.8 24.8 12.8 19.8 13.6 9.1 8.6 11.4 17.0 10.8 20.4 21.3 9.0 12.8 8.2 16.2 13.5 9.5 9.7 8.3 12.5 19.2 9.8 5.4 13.0 17.0 7.9 10.0 17.5 15.6 5.3 14.4 9.1 11.3 10.1 9.1 5.9 7.2 8.7 7.5 13.1 9.2 5.5 9.1 10.8 12.7 6.7 5.5 12.6 5.7 7.6 6.7 7.2 9.2 6.4 6.1 7.3 6.9 5.3 5.3 8.1 8.8 9.7 17.2 7.1 7.9 5.2 8.7 7.8 3.0 3.4 8.5 5.4 9.6 11.8 7.2 5.9 10.1 10.6 28.6 8.8 6.2 5.1 7.4 5.1 8.0 5.8 9.7 8.1 6.5 14.1 7.8 39.8 12.1 6.6 3.3 3.9 9.6 15.1 7.1 9.2 7.6 15.4 9.0 7.8 4.6 6.0 8.7 6.3 2.5 7.8 7.5 8.4 5.2 8.4 7.3 7.2 5.9 6.5 7.4 1.8 13.1 4.0 4.6 9.2 5.5 13.2 13.6 14.3 16.8 12.8 19.8 17.0 10.8 16.2 15.6 WRN "RECQ3, RECQL2" ENSG00000165392 "Werner syndrome RecQ like helicase" Q14191 8 31033801-31173769 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028661 Approved Supported "Nuclear speckles" "Nuclear speckles" "HPA028661: AB_10602255" "unprognostic (8.73e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-3)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-2)" "unprognostic (6.63e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-2)" "unprognostic (2.66e-1)" 10.1 9.2 5.6 8.5 6.6 15.6 11.1 10.7 7.3 14.2 8.0 7.7 7.7 5.5 24.4 8.8 7.6 9.7 6.9 7.0 5.9 4.0 5.1 7.7 7.2 6.7 8.2 5.3 12.0 9.9 7.8 28.1 8.5 7.0 8.6 7.8 8.3 10.8 7.8 7.7 10.2 7.0 12.1 14.9 8.9 8.3 10.4 7.3 11.8 7.9 6.3 9.3 10.8 8.7 3.9 2.7 1.3 1.9 2.9 6.2 1.6 6.4 6.3 13.1 8.3 7.8 12.5 8.3 7.3 7.1 8.9 9.3 4.0 3.9 15.1 6.7 7.3 3.3 8.1 5.2 13.4 4.2 6.9 15.4 6.0 3.3 9.8 9.1 5.7 9.1 5.8 8.5 10.2 8.6 24.3 9.6 8.2 4.1 18.9 4.4 11.2 4.6 10.9 9.9 6.0 3.7 7.0 2.8 7.5 8.8 5.0 6.9 3.5 4.5 13.7 9.7 6.0 5.0 6.1 2.5 2.7 19.0 7.2 7.2 6.6 1.2 1.9 1.3 3.3 1.9 6.2 3.9 3.8 3.3 2.7 3.5 2.5 3.2 0.5 2.9 0.8 2.0 2.8 1.6 5.6 6.6 10.7 7.3 5.9 4.0 8.2 5.3 7.0 7.3 WRNIP1 "bA420G6.2, FLJ22526, WHIP" ENSG00000124535 "Werner helicase interacting protein 1" Q96S55 6 2765414-2786952 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031752, HPA031753" Enhanced Approved Nucleoplasm Nucleoplasm "HPA031752: AB_10603004, HPA031753: AB_2674028" "unprognostic (5.52e-2)" "unprognostic (5.95e-2)" "unprognostic (6.83e-3)" "unprognostic (8.35e-3)" "unprognostic (7.66e-2)" "unprognostic (7.10e-2)" "unprognostic (5.63e-3)" "unprognostic (3.40e-2)" "unprognostic (1.39e-2)" "unprognostic (1.73e-2)" "unprognostic (1.81e-1)" "unprognostic (6.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.37e-1)" "unprognostic (2.61e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" 15.4 23.1 29.9 19.8 32.1 31.2 22.4 42.5 33.5 22.2 21.9 23.3 25.7 17.7 19.8 29.7 32.8 28.0 24.7 28.8 30.9 30.1 23.3 25.8 21.2 23.4 27.4 26.2 23.2 37.4 39.2 31.2 32.3 21.3 22.5 22.6 23.9 34.6 22.0 29.0 27.8 19.6 18.5 20.2 20.7 19.3 24.6 24.2 34.1 31.6 36.0 25.3 18.8 29.2 3.4 4.2 9.1 2.8 3.7 6.5 2.3 31.0 15.6 15.9 26.1 16.9 14.6 21.2 14.3 20.1 26.3 26.3 24.6 14.5 27.9 38.9 18.4 24.2 26.0 28.7 25.8 27.8 28.6 29.1 17.7 38.4 19.3 18.3 20.2 14.8 23.5 24.1 26.3 33.2 22.2 10.1 19.1 30.3 27.0 33.2 13.6 19.4 21.6 23.3 28.2 27.9 19.2 48.1 13.7 16.8 17.2 33.2 22.1 20.6 18.0 19.8 14.9 17.1 34.4 13.0 22.7 21.6 7.7 19.9 26.7 9.1 2.6 3.4 6.5 2.8 2.1 3.4 4.7 4.8 2.1 2.4 5.5 5.2 1.1 3.7 1.4 4.2 6.5 2.3 29.9 32.1 42.5 33.5 30.9 30.1 27.4 26.2 21.3 24.2 XPNPEP1 "XPNPEP, XPNPEPL, XPNPEPL1" ENSG00000108039 "X-prolyl aminopeptidase 1" Q9NQW7 10 109864766-109923553 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025196, HPA030419, HPA030420, HPA030422" Supported Enhanced Cytosol 760000 Cytosol "CAB025196: , HPA030419: AB_10598917, HPA030420: AB_10611523, HPA030422: AB_10601783" "unprognostic (3.17e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (2.46e-1)" "unprognostic (2.01e-3)" "prognostic unfavourable (2.12e-5)" "unprognostic (8.03e-2)" "unprognostic (2.10e-2)" "unprognostic (1.88e-1)" "unprognostic (4.89e-2)" "unprognostic (7.61e-2)" "unprognostic (2.43e-2)" "unprognostic (1.34e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (5.18e-2)" 16.6 14.7 13.4 16.1 18.9 12.8 13.6 14.8 22.2 15.7 20.6 19.5 14.1 33.2 17.5 16.1 17.8 15.8 20.3 17.8 13.7 11.4 18.3 21.0 14.8 14.9 13.8 14.0 17.8 46.0 14.9 15.9 19.0 17.2 16.0 26.9 15.6 19.6 11.3 18.5 20.4 38.6 18.6 11.9 18.0 16.8 15.1 12.0 9.9 15.7 15.2 24.2 14.1 13.8 5.5 24.0 10.0 21.0 14.7 10.6 13.4 25.3 11.2 17.9 24.4 29.2 27.5 13.7 14.2 28.9 21.3 23.1 21.7 21.9 36.3 12.3 21.8 13.5 14.2 17.5 20.9 10.7 13.6 24.2 7.3 9.0 20.4 18.8 20.2 27.0 10.9 23.4 20.8 34.9 7.8 11.6 27.0 8.6 13.4 11.7 7.0 12.1 15.1 36.1 6.5 27.0 8.0 5.4 20.8 12.3 7.8 23.6 9.5 17.6 17.9 8.7 11.4 13.7 12.4 19.8 9.6 31.0 20.5 26.4 6.8 10.0 13.7 5.6 10.6 21.0 7.3 5.5 7.0 9.5 24.0 4.8 5.0 6.6 1.1 14.7 17.5 18.8 7.5 13.4 13.4 18.9 14.8 22.2 13.7 11.4 13.8 14.0 17.2 12.0 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738974-129769538 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "intestine: 145.6;kidney: 49.7" "Cell line enhanced" "Detected in some" "ASC diff: 6.2;ASC TERT1: 32.6;HSkMC: 16.5" "Group enriched" "Detected in many" 6 "colorectal cancer: 5.3;liver cancer: 18.3;stomach cancer: 3.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 7.3;intermediate monocyte: 2.1;MAIT T-cell: 2.2;memory CD4 T-cell: 2.4;memory CD8 T-cell: 4.8;naive CD8 T-cell: 3.6;non-classical monocyte: 4.4;T-reg: 2.2" "Group enriched" "Detected in many" 7 "monocytes: 4.4;T-cells: 7.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" 8900000 "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 4.7 0.5 0.0 1.1 0.1 0.0 3.2 0.0 0.1 1.7 57.4 0.1 0.8 37.0 1.2 1.7 4.2 3.4 1.3 2.6 0.0 0.0 49.7 8.0 1.0 1.2 0.0 0.0 3.5 0.9 0.0 0.0 0.6 0.1 3.6 2.0 0.7 0.7 0.3 1.6 2.1 145.6 2.5 0.1 0.2 1.7 1.2 0.0 0.1 0.9 1.4 0.3 4.0 10.7 0.4 0.8 0.2 4.4 0.0 7.3 1.3 0.0 0.0 0.4 0.0 6.2 32.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.8 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 7.3 2.1 2.2 0.0 2.4 4.8 0.3 0.4 0.7 3.6 0.2 0.0 4.4 0.8 2.2 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 XPNPEP3 "APP3, ICP55, NPHPL1" ENSG00000196236 "X-prolyl aminopeptidase 3" Q9NQH7 22 40857077-40932815 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000527 Approved "HPA000527: AB_1079266" "prognostic unfavourable (8.19e-4)" "unprognostic (6.77e-2)" "unprognostic (3.22e-3)" "unprognostic (5.03e-3)" "unprognostic (6.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (2.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (6.69e-2)" "unprognostic (8.00e-3)" "unprognostic (2.49e-1)" "prognostic unfavourable (6.10e-4)" "unprognostic (1.24e-1)" 8.2 13.6 7.5 5.8 9.2 4.7 9.7 5.2 7.8 7.3 6.1 10.8 11.6 32.3 10.7 12.3 7.2 9.4 10.5 11.2 7.6 7.1 9.8 19.0 6.6 10.6 7.9 6.1 10.7 10.5 8.0 15.0 6.1 10.7 7.3 6.2 9.3 8.5 13.6 12.0 11.5 20.9 7.1 9.3 7.7 6.8 18.9 8.2 11.5 9.1 7.3 8.8 12.6 8.2 5.9 6.0 6.4 10.0 1.2 4.4 4.0 3.2 4.7 3.2 7.0 9.0 6.0 2.2 4.1 3.1 2.3 2.3 3.9 2.1 6.5 2.3 7.9 7.6 6.0 3.2 3.4 3.9 12.4 4.2 9.3 7.3 4.1 7.3 0.7 5.2 5.0 7.2 4.3 4.0 3.5 5.9 4.8 5.0 3.5 3.9 1.9 9.6 4.9 4.3 3.7 6.4 4.4 2.8 2.5 4.0 6.1 3.8 7.1 3.3 4.0 4.7 4.1 4.3 2.4 5.5 4.2 7.9 7.2 9.6 3.2 4.0 4.4 4.4 3.4 3.9 1.8 5.9 2.1 2.2 3.1 3.7 4.4 3.3 6.4 1.2 10.0 6.0 3.0 4.0 7.5 9.2 5.2 7.8 7.6 7.1 7.9 6.1 10.7 8.2 YOD1 "DKFZp451J1719, DUBA8, OTUD2" ENSG00000180667 "YOD1 deubiquitinase" Q5VVQ6 1 207043849-207052980 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Unfolded protein response" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.7" "Cell line enhanced" "Detected in many" "HEL: 39.4;K-562: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028400, HPA028439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" 40000 "Nucleoplasm, Plasma membrane, Cytosol" "HPA028400: AB_10599854, HPA028439: AB_10600994" "unprognostic (3.69e-2)" "unprognostic (8.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (2.03e-2)" "unprognostic (3.28e-2)" "unprognostic (9.87e-3)" "unprognostic (9.38e-2)" "unprognostic (2.31e-3)" "unprognostic (8.96e-2)" "unprognostic (1.47e-3)" "unprognostic (1.03e-2)" "unprognostic (6.07e-2)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (1.79e-2)" "unprognostic (3.62e-1)" 4.5 4.6 4.0 4.0 5.3 44.7 6.6 4.8 7.5 6.1 3.9 7.6 2.6 4.1 4.0 3.1 24.5 3.7 3.5 5.0 4.0 2.2 4.5 5.2 9.4 4.2 7.1 4.4 3.5 3.6 2.5 5.1 6.3 5.1 3.4 4.0 3.4 9.7 3.0 6.5 14.9 4.8 2.7 8.5 5.2 8.4 5.6 6.9 14.3 5.8 10.0 8.2 5.8 12.3 0.5 1.3 3.9 1.5 1.2 1.8 0.9 5.3 2.8 4.5 2.7 1.6 2.1 8.8 3.5 2.7 2.7 2.7 5.4 5.5 2.8 1.4 2.1 5.9 0.0 4.3 3.0 2.2 4.8 39.4 11.6 2.5 1.5 5.1 13.9 1.5 3.4 2.2 8.4 2.3 27.4 0.0 2.3 0.0 4.5 2.8 4.3 6.4 2.3 0.2 2.0 2.7 6.0 2.3 5.2 5.8 6.7 7.6 2.4 3.6 1.1 2.3 6.1 1.9 4.6 4.5 0.2 4.2 2.7 0.0 1.5 3.9 1.2 2.0 1.1 1.5 1.5 0.4 1.7 0.9 1.3 0.5 1.4 1.8 2.9 1.2 1.0 0.7 0.8 0.9 4.0 5.3 4.8 7.5 4.0 2.2 7.1 4.4 5.1 6.9 YTHDC2 "DKFZp564A186, FLJ10053, FLJ2194" ENSG00000047188 "YTH domain containing 2" Q9H6S0 5 113513683-113595285 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037364, HPA072678" Approved Approved "Nucleoplasm,Nuclear bodies,Cytoplasmic bodies" Nucleoplasm "Nuclear bodies, Cytoplasmic bodies" "HPA037364: AB_10672788, HPA072678: " "unprognostic (2.09e-1)" "unprognostic (2.10e-1)" "prognostic favourable (1.82e-5)" "unprognostic (4.33e-3)" "unprognostic (1.45e-1)" "unprognostic (6.48e-3)" "unprognostic (1.96e-1)" "unprognostic (7.82e-3)" "unprognostic (3.55e-2)" "unprognostic (8.56e-3)" "unprognostic (4.61e-2)" "unprognostic (2.03e-1)" "unprognostic (4.15e-2)" "unprognostic (3.05e-1)" "unprognostic (9.96e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" 15.2 16.3 12.4 18.5 16.8 12.8 15.3 25.2 26.1 16.5 12.7 11.7 9.0 13.6 17.7 14.6 16.1 14.2 12.2 13.0 10.4 10.5 14.3 18.3 12.4 18.7 12.8 10.2 19.9 14.7 35.5 26.2 10.3 18.6 12.8 15.3 14.9 15.5 13.3 18.5 16.5 16.5 13.2 13.7 19.3 13.4 20.5 13.3 19.7 16.2 15.4 18.4 14.7 14.8 9.5 5.5 4.2 4.9 5.7 5.7 1.7 11.1 10.0 13.1 22.0 7.3 9.7 14.3 8.6 9.6 11.1 17.3 7.0 6.3 20.3 6.2 7.2 10.9 15.7 19.3 14.5 8.7 14.2 11.0 18.0 9.4 10.8 8.8 9.8 7.9 7.5 6.9 12.8 15.3 10.8 9.4 9.7 3.7 12.1 6.3 6.0 6.6 5.1 11.3 15.7 9.2 14.8 10.5 8.8 11.6 8.5 8.8 11.9 7.9 13.3 17.0 5.9 8.7 11.7 9.6 12.0 12.7 9.8 10.1 7.2 0.0 4.3 4.2 4.5 2.8 5.3 9.5 5.3 4.8 3.6 8.1 5.7 4.7 1.8 5.7 4.9 5.5 3.7 1.7 12.4 16.8 25.2 26.1 10.4 10.5 12.8 10.2 18.6 13.3 ZMPSTE24 "FACE-1, HGPS, PRO1, STE24, Ste24p" ENSG00000084073 "Zinc metallopeptidase STE24" O75844 1 40258107-40294184 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006988 Approved Approved "Golgi apparatus,Cytosol" 13000 Cytosol "Golgi apparatus" "HPA006988: AB_1080659" "unprognostic (6.32e-2)" "unprognostic (1.63e-2)" "unprognostic (3.75e-3)" "unprognostic (4.63e-2)" "unprognostic (4.16e-3)" "unprognostic (1.37e-1)" "prognostic unfavourable (5.73e-6)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.84e-3)" "unprognostic (4.78e-2)" "unprognostic (7.96e-2)" "unprognostic (5.06e-2)" "unprognostic (3.65e-2)" "unprognostic (2.65e-1)" "prognostic unfavourable (6.34e-4)" "unprognostic (2.71e-2)" 21.6 24.2 17.6 15.4 19.6 6.5 18.6 10.7 21.3 20.9 20.6 14.9 27.0 17.9 29.7 19.7 21.4 19.9 20.7 20.8 17.1 16.9 34.2 48.7 16.2 23.1 21.9 17.0 16.0 20.4 39.8 17.0 23.0 23.5 21.7 23.3 15.6 18.9 19.0 19.1 14.7 20.9 25.2 19.2 17.7 19.0 10.7 17.9 20.9 20.6 14.7 18.4 19.1 16.7 15.1 25.8 15.1 23.9 24.2 22.5 20.3 20.7 13.9 10.8 8.1 28.7 23.0 21.0 21.8 18.2 24.6 22.5 15.1 36.0 17.9 15.1 26.6 21.6 22.0 20.0 28.4 16.8 14.1 17.3 14.8 13.8 16.4 27.8 21.7 16.6 20.6 21.0 9.1 17.3 18.3 18.0 23.3 9.7 16.8 8.3 20.7 14.5 14.6 19.2 22.2 21.8 20.1 11.3 13.3 20.1 44.9 27.0 16.5 76.8 17.1 22.3 16.3 20.7 26.4 11.1 29.6 15.6 24.4 19.5 23.6 15.1 20.0 13.6 17.9 23.9 21.5 15.1 19.1 18.9 25.8 11.6 17.0 22.5 11.8 24.2 22.7 16.9 22.3 20.3 17.6 19.6 10.7 21.3 17.1 16.9 21.9 17.0 23.5 17.9 ZRANB1 TRABID ENSG00000019995 "Zinc finger RANBP2-type containing 1" Q9UGI0 10 124942123-124988189 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029239, HPA029240, HPA029241" Approved Supported Nucleoplasm,Cytosol Nucleoplasm Cytosol "HPA029239: AB_10599419, HPA029240: AB_10601450, HPA029241: AB_10602205" "unprognostic (2.06e-1)" "unprognostic (5.16e-2)" "unprognostic (6.96e-2)" "unprognostic (1.67e-1)" "unprognostic (1.40e-1)" "unprognostic (9.53e-3)" "unprognostic (4.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (4.20e-1)" "unprognostic (1.46e-1)" "unprognostic (1.22e-2)" "unprognostic (1.60e-1)" "unprognostic (2.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.47e-2)" 5.1 9.3 4.9 1.9 4.7 7.9 5.3 11.9 6.0 6.3 5.2 1.4 5.9 5.2 4.1 4.4 3.6 7.3 4.6 4.0 4.2 10.4 4.2 2.5 4.4 8.6 3.1 7.1 3.9 3.9 4.6 3.3 3.4 5.8 18.0 5.2 3.0 6.3 3.8 2.8 3.6 7.7 3.8 3.9 4.2 4.8 3.4 1.4 4.6 1.1 3.8 4.4 0.8 7.7 4.4 9.5 6.9 14.8 12.5 4.0 7.6 20.8 14.5 16.9 6.6 6.1 8.1 5.7 9.6 5.6 12.0 5.6 19.6 8.6 5.9 4.6 5.1 7.1 31.6 6.9 3.5 13.8 16.5 10.6 22.8 9.1 0.6 6.7 7.8 6.1 8.1 6.0 3.4 4.8 7.0 6.7 3.6 6.4 5.6 4.8 8.1 6.4 5.0 8.4 5.5 5.9 6.7 6.2 6.4 5.1 9.4 7.2 6.2 9.4 7.0 4.9 3.0 2.1 1.1 3.0 2.2 0.4 1.9 2.4 2.6 2.2 0.9 3.4 4.4 3.3 4.6 3.8 0.5 1.4 2.2 0.8